# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- E1-E2_ATPase PF00122.20 KFM56500.1 - 2.7e-29 102.0 0.0 7.3e-29 100.6 0.0 1.6 1 1 1 2 2 2 1 E1-E2 ATPase Phage_Gp23 PF10669.9 KFM56500.1 - 4.4 7.7 5.0 0.39 11.0 0.4 1.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) HTH_Tnp_4 PF13613.6 KFM56501.1 - 4.6e-12 45.5 0.1 6.5e-12 45.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 KFM56501.1 - 8.8e-06 25.5 0.1 1.3e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease LRR_8 PF13855.6 KFM56502.1 - 4.6e-18 64.7 6.4 2.3e-08 33.7 0.5 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_5 PF13306.6 KFM56502.1 - 2.1e-09 37.4 0.2 5.2e-09 36.2 0.2 1.7 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM56502.1 - 2.1e-07 31.2 8.6 0.023 15.1 0.2 4.4 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM56502.1 - 3.1e-06 27.0 2.7 6.2 7.8 0.3 6.2 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 KFM56502.1 - 0.0073 16.3 6.1 17 5.8 0.5 5.4 6 0 0 6 6 6 1 Leucine Rich repeat LRR_12 PF18837.1 KFM56502.1 - 0.11 12.2 0.0 4.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeat PDGF PF00341.17 KFM56503.1 - 7.4e-09 35.8 9.6 8.5e-09 35.6 8.9 1.4 1 1 0 1 1 1 1 PDGF/VEGF domain Herpes_U44 PF04533.13 KFM56503.1 - 0.1 12.2 0.1 0.19 11.3 0.1 1.4 1 1 0 1 1 1 0 Herpes virus U44 protein RTBV_P12 PF06361.11 KFM56504.1 - 6.3 7.3 8.2 8.4 6.8 0.4 2.3 1 1 1 2 2 2 0 Rice tungro bacilliform virus P12 protein BTB PF00651.31 KFM56505.1 - 7.7e-10 39.0 0.1 1.7e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM56505.1 - 0.002 18.2 3.4 0.33 11.1 0.2 3.6 3 1 1 4 4 4 2 BTB And C-terminal Kelch DUF1473 PF07341.11 KFM56505.1 - 0.59 9.9 8.3 0.14 12.0 2.1 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1473) Exo_endo_phos_2 PF14529.6 KFM56507.1 - 8.6e-15 54.6 1.9 1.5e-14 53.8 1.9 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM56507.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_2 PF07727.14 KFM56508.1 - 4.6e-63 213.1 0.0 6.1e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 KFM56510.1 - 1.5e-13 50.9 0.3 2.1e-13 50.3 0.3 1.2 1 0 0 1 1 1 1 Putative peptidase (DUF1758) ABC_tran PF00005.27 KFM56511.1 - 4.5e-29 101.7 0.0 6.5e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM56511.1 - 7e-12 45.8 0.8 1.4e-07 31.6 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFM56511.1 - 0.0019 18.6 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KFM56511.1 - 0.0071 15.8 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 KFM56511.1 - 0.014 15.4 0.2 0.028 14.3 0.2 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KFM56511.1 - 0.016 15.7 1.5 0.025 15.1 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KFM56511.1 - 0.034 14.6 0.2 0.061 13.7 0.2 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM56511.1 - 0.046 14.0 0.2 0.098 12.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFM56511.1 - 0.075 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 KFM56511.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KFM56511.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KFM56511.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KFM56511.1 - 0.23 11.4 0.5 0.42 10.5 0.1 1.5 2 0 0 2 2 2 0 Rad17 P-loop domain FAM92 PF06730.11 KFM56512.1 - 7e-30 104.1 2.0 8.5e-30 103.8 2.0 1.0 1 0 0 1 1 1 1 FAM92 protein AalphaY_MDB PF04611.12 KFM56512.1 - 0.0001 22.3 0.1 0.00079 19.5 0.0 2.1 1 1 1 2 2 2 1 Mating type protein A alpha Y mating type dependent binding region BAR_3 PF16746.5 KFM56512.1 - 0.00013 21.8 3.7 0.00019 21.2 3.7 1.2 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 KFM56512.1 - 0.0013 18.5 1.4 0.0023 17.6 1.3 1.4 1 1 0 1 1 1 1 BAR domain Vps5 PF09325.10 KFM56512.1 - 0.0034 17.0 5.1 0.0063 16.1 5.1 1.4 1 1 0 1 1 1 1 Vps5 C terminal like Syntaxin_2 PF14523.6 KFM56512.1 - 0.0045 17.3 2.7 0.0064 16.8 0.2 2.0 1 1 1 2 2 2 1 Syntaxin-like protein DUF1041 PF06292.17 KFM56512.1 - 0.01 16.2 0.2 0.024 15.0 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) MAGE PF01454.19 KFM56512.1 - 0.017 14.8 0.6 0.028 14.1 0.6 1.3 1 0 0 1 1 1 0 MAGE family Muted PF14942.6 KFM56512.1 - 0.083 13.2 5.1 1.3 9.3 2.0 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Peptidase_C1 PF00112.23 KFM56515.1 - 1.8e-68 230.9 7.2 2.1e-68 230.7 7.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 KFM56515.1 - 1.4e-20 72.9 0.1 2.9e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 KFM56515.1 - 0.00037 19.4 0.5 0.062 12.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family 5_nucleotid_C PF02872.18 KFM56516.1 - 8.3e-21 74.8 0.0 1.2e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KFM56516.1 - 3.2e-16 60.5 0.2 4.8e-16 59.9 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HTH_Tnp_ISL3 PF13542.6 KFM56517.1 - 0.0076 15.6 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 SpoIIID PF12116.8 KFM56517.1 - 0.024 14.7 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein D GerE PF00196.19 KFM56517.1 - 0.064 12.8 0.2 0.087 12.4 0.2 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 KFM56517.1 - 0.096 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.6 KFM56517.1 - 0.099 12.4 0.7 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 KFM56517.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain LacI PF00356.21 KFM56517.1 - 0.11 12.3 0.5 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_23 PF13384.6 KFM56517.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 KFM56517.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 KFM56517.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 HTH DNA binding domain Amidase PF01425.21 KFM56518.1 - 1.3e-117 393.5 0.0 1.3e-80 271.6 0.0 2.0 2 0 0 2 2 2 2 Amidase DUF5605 PF18310.1 KFM56518.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) GRP PF07172.11 KFM56519.1 - 0.00049 20.7 3.4 0.00074 20.2 3.4 1.4 1 1 0 1 1 1 1 Glycine rich protein family FAM176 PF14851.6 KFM56519.1 - 0.00066 19.4 3.4 0.00075 19.2 3.4 1.1 1 0 0 1 1 1 1 FAM176 family Pro-rich PF15240.6 KFM56519.1 - 0.011 16.0 0.1 0.012 15.9 0.1 1.1 1 0 0 1 1 1 0 Proline-rich Connexin PF00029.19 KFM56519.1 - 0.011 15.5 2.2 0.013 15.2 2.2 1.1 1 0 0 1 1 1 0 Connexin Conotoxin PF02950.17 KFM56519.1 - 0.024 15.6 0.7 0.045 14.8 0.7 1.5 1 1 0 1 1 1 0 Conotoxin 6PF2K PF01591.18 KFM56519.1 - 0.028 13.7 0.3 0.031 13.6 0.3 1.0 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Tmemb_9 PF05434.11 KFM56519.1 - 0.032 14.1 0.1 0.04 13.8 0.1 1.2 1 0 0 1 1 1 0 TMEM9 Ureide_permease PF07168.11 KFM56519.1 - 0.035 12.8 0.9 0.036 12.8 0.9 1.0 1 0 0 1 1 1 0 Ureide permease TRAP_alpha PF03896.16 KFM56519.1 - 0.041 13.1 1.1 0.046 12.9 1.1 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ETRAMP PF09716.10 KFM56519.1 - 0.073 13.1 5.3 0.18 11.9 5.3 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF5531 PF17671.1 KFM56519.1 - 0.074 12.9 2.5 0.1 12.4 2.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5531) O-antigen_lig PF13425.6 KFM56519.1 - 0.083 11.7 1.5 0.087 11.6 1.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Phage_Gp23 PF10669.9 KFM56519.1 - 0.1 13.0 10.7 0.17 12.2 10.7 1.3 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) OAD_gamma PF04277.13 KFM56519.1 - 0.15 12.7 6.8 0.43 11.2 6.8 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CLN3 PF02487.17 KFM56519.1 - 0.22 10.5 0.4 0.23 10.5 0.4 1.0 1 0 0 1 1 1 0 CLN3 protein Folate_carrier PF01770.18 KFM56519.1 - 0.3 9.8 1.0 0.31 9.7 1.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier SID-1_RNA_chan PF13965.6 KFM56519.1 - 0.3 9.4 0.3 0.31 9.4 0.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GOLD_2 PF13897.6 KFM56519.1 - 0.32 11.5 4.1 0.39 11.2 4.1 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Serinc PF03348.15 KFM56519.1 - 0.35 9.7 1.4 0.4 9.6 1.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4637 PF15470.6 KFM56519.1 - 0.36 10.5 8.3 0.44 10.3 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Eapp_C PF10238.9 KFM56519.1 - 0.44 10.6 4.7 0.51 10.4 4.7 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF809 PF05663.11 KFM56519.1 - 0.6 10.2 11.3 0.77 9.9 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) TMEM214 PF10151.9 KFM56519.1 - 1.2 7.5 5.8 1.3 7.4 5.8 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator RNA_pol_Rpc4 PF05132.14 KFM56519.1 - 1.3 9.5 7.8 1.5 9.2 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 YqfQ PF14181.6 KFM56519.1 - 1.9 8.7 8.2 2.2 8.5 8.2 1.0 1 0 0 1 1 1 0 YqfQ-like protein RAP1 PF07218.11 KFM56519.1 - 4.5 5.4 8.9 5.1 5.3 8.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RR_TM4-6 PF06459.12 KFM56519.1 - 5.3 6.8 12.2 6.1 6.6 12.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KFM56519.1 - 6.5 4.9 9.7 7.7 4.7 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein SHR3_chaperone PF08229.11 KFM56519.1 - 9.2 5.2 6.2 7.5 5.5 5.4 1.3 1 1 0 1 1 1 0 ER membrane protein SH3 PRE_C2HC PF07530.11 KFM56520.1 - 3.4e-08 33.5 0.4 7.9e-08 32.3 0.2 1.7 2 0 0 2 2 2 1 Associated with zinc fingers zf-RanBP PF00641.18 KFM56520.1 - 0.32 10.3 4.7 4.8 6.6 0.1 3.2 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-H2C2_2 PF13465.6 KFM56521.1 - 1.7e-47 157.8 57.2 3.8e-07 30.2 2.5 8.1 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM56521.1 - 3.9e-29 99.4 72.8 2.7e-05 24.4 2.4 7.6 8 0 0 8 8 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM56521.1 - 4.7e-19 67.4 65.4 0.0013 19.4 0.9 7.6 8 0 0 8 8 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM56521.1 - 1.4e-13 50.5 57.0 0.023 14.7 0.9 8.6 8 1 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.7 KFM56521.1 - 1.1e-10 41.5 48.5 0.0065 16.8 0.7 7.9 7 1 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM56521.1 - 6.2e-07 29.5 43.9 0.0091 16.3 3.2 7.9 8 1 0 8 8 7 3 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 KFM56521.1 - 1.7e-06 28.0 21.1 0.56 10.4 0.3 7.2 7 0 0 7 7 7 1 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM56521.1 - 1.9e-06 27.7 26.7 0.092 12.7 0.2 6.1 4 2 2 6 6 6 3 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 KFM56521.1 - 7.5e-06 26.0 26.0 0.31 11.2 0.2 6.1 3 3 4 7 7 7 3 Zinc ribbon domain Endonuclease_7 PF02945.15 KFM56521.1 - 0.0007 19.5 30.1 0.056 13.4 1.4 4.1 1 1 3 4 4 4 3 Recombination endonuclease VII zf-C2H2_3rep PF18868.1 KFM56521.1 - 0.0042 17.8 22.0 2.4 8.9 0.4 5.6 3 2 1 4 4 4 1 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 KFM56521.1 - 0.012 16.3 22.3 0.77 10.5 4.0 4.1 1 1 2 3 3 3 0 zinc-ribbon family zf_UBZ PF18439.1 KFM56521.1 - 0.02 14.5 23.6 4.1 7.1 0.1 7.2 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 KFM56521.1 - 0.031 14.3 20.3 13 6.0 0.0 6.9 7 0 0 7 7 7 0 XPA protein N-terminal zf-C2HE PF16278.5 KFM56521.1 - 0.031 14.7 3.1 0.031 14.7 3.1 5.8 3 3 3 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFM56521.1 - 0.12 12.7 41.8 2.9 8.3 0.8 6.3 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM56521.1 - 0.32 11.0 28.7 0.42 10.6 0.3 6.8 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-FCS PF06467.14 KFM56521.1 - 0.42 10.6 0.1 0.42 10.6 0.1 6.2 5 1 2 7 7 6 0 MYM-type Zinc finger with FCS sequence motif zf-trcl PF13451.6 KFM56521.1 - 0.52 10.3 26.0 28 4.7 0.6 6.9 6 1 0 6 6 6 0 Probable zinc-ribbon domain zf_C2H2_13 PF18508.1 KFM56521.1 - 0.89 9.2 21.2 4.3 7.0 1.2 5.4 6 0 0 6 6 6 0 Zinc finger domain zf-FPG_IleRS PF06827.14 KFM56521.1 - 1.2 9.1 18.2 12 5.8 0.1 6.0 6 0 0 6 6 6 0 Zinc finger found in FPG and IleRS zf-CCHC_2 PF13696.6 KFM56521.1 - 2.2 8.2 33.9 0.17 11.7 1.3 7.0 7 0 0 7 7 7 0 Zinc knuckle zf-Sec23_Sec24 PF04810.15 KFM56521.1 - 3.2 7.9 23.1 0.12 12.5 0.9 6.1 6 1 1 7 7 7 0 Sec23/Sec24 zinc finger DUF3268 PF11672.8 KFM56521.1 - 7.3 6.9 22.3 2.3 8.6 0.7 4.6 1 1 2 5 5 5 0 zinc-finger-containing domain zf_ZIC PF18366.1 KFM56521.1 - 8.2 6.6 35.4 0.088 12.9 2.1 6.8 2 2 5 7 7 7 0 Zic proteins zinc finger domain FYDLN_acid PF09538.10 KFM56521.1 - 9.4 7.0 14.5 19 6.0 0.1 5.1 1 1 5 7 7 7 0 Protein of unknown function (FYDLN_acid) DDE_Tnp_IS1595 PF12762.7 KFM56523.1 - 0.027 14.5 0.1 0.028 14.4 0.1 1.0 1 0 0 1 1 1 0 ISXO2-like transposase domain Ion_trans PF00520.31 KFM56525.1 - 3.2e-49 167.4 6.2 4.3e-49 166.9 6.2 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFM56525.1 - 1.3e-29 102.3 0.0 3.2e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFM56525.1 - 1.6e-12 47.2 2.6 1.6e-12 47.2 2.6 2.3 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFM56525.1 - 0.02 13.6 0.7 0.035 12.8 0.5 1.4 1 1 0 1 1 1 0 Polycystin cation channel Lipase PF00151.19 KFM56526.1 - 5.4e-09 35.8 2.2 6e-09 35.6 2.2 1.0 1 0 0 1 1 1 1 Lipase ZIP4_domain PF18292.1 KFM56526.1 - 0.067 13.1 0.0 0.081 12.9 0.0 1.1 1 0 0 1 1 1 0 Zinc transporter ZIP4 domain DUF4986 PF16375.5 KFM56527.1 - 0.074 13.7 0.1 0.19 12.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function Astacin PF01400.24 KFM56528.1 - 9.2e-47 159.1 0.0 1.1e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM56528.1 - 0.0044 16.9 0.3 0.16 11.8 0.2 2.2 1 1 1 2 2 2 1 Matrixin Reprolysin_3 PF13582.6 KFM56528.1 - 0.038 14.5 0.2 0.055 14.0 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFM56529.1 - 1.1e-48 165.4 0.0 1.4e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM56529.1 - 0.0025 17.7 0.7 0.14 12.0 0.2 2.2 1 1 1 2 2 2 2 Matrixin Reprolysin_3 PF13582.6 KFM56529.1 - 0.012 16.1 0.1 0.017 15.7 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM56529.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.24 KFM56530.1 - 2.4e-47 161.0 0.0 2.7e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM56530.1 - 0.0041 17.0 0.4 0.051 13.4 0.2 2.0 1 1 0 2 2 2 1 Matrixin Reprolysin_3 PF13582.6 KFM56530.1 - 0.023 15.2 0.2 0.033 14.7 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM56530.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.24 KFM56531.1 - 6.3e-55 185.8 0.0 7.3e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM56531.1 - 0.0099 15.7 0.4 0.22 11.3 0.2 2.4 1 1 1 2 2 2 1 Matrixin Reprolysin_3 PF13582.6 KFM56531.1 - 0.046 14.2 0.2 0.069 13.7 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM56531.1 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.24 KFM56532.1 - 1.3e-50 171.7 0.0 1.5e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM56532.1 - 0.016 15.1 0.3 0.13 12.0 0.2 2.0 1 1 0 2 2 2 0 Matrixin Peptidase_M66 PF10462.9 KFM56532.1 - 0.056 12.4 0.2 0.077 11.9 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 KFM56532.1 - 0.17 12.4 0.2 0.26 11.8 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFM56533.1 - 7.3e-58 195.3 0.2 8.6e-58 195.1 0.2 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM56533.1 - 0.06 13.2 0.2 0.12 12.2 0.1 1.6 1 1 0 1 1 1 0 Matrixin ARL2_Bind_BART PF11527.8 KFM56533.1 - 0.086 12.9 0.1 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART DUF956 PF06115.11 KFM56533.1 - 0.095 12.4 0.2 0.22 11.2 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF956) Peptidase_M8 PF01457.16 KFM56533.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Leishmanolysin Astacin PF01400.24 KFM56534.1 - 3.4e-12 46.4 0.2 3.5e-12 46.3 0.2 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 KFM56535.1 - 7.5e-36 123.5 0.0 9.2e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M8 PF01457.16 KFM56535.1 - 0.026 13.2 0.0 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin Peptidase_M10 PF00413.24 KFM56535.1 - 0.053 13.4 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Matrixin DUF3810 PF12725.7 KFM56535.1 - 0.073 12.4 0.6 0.11 11.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_M66 PF10462.9 KFM56535.1 - 0.074 12.0 0.6 0.098 11.6 0.6 1.1 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 KFM56535.1 - 0.17 12.4 0.2 0.23 12.0 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFM56536.1 - 2.1e-48 164.5 0.0 2.4e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M8 PF01457.16 KFM56536.1 - 0.042 12.5 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin Peptidase_M10 PF00413.24 KFM56536.1 - 0.079 12.8 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Matrixin DUF3810 PF12725.7 KFM56536.1 - 0.1 11.9 0.6 0.16 11.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Shisa PF13908.6 KFM56537.1 - 1.2e-08 35.4 24.4 5e-05 23.6 7.4 2.3 1 1 1 2 2 2 2 Wnt and FGF inhibitory regulator RCR PF12273.8 KFM56537.1 - 0.0056 17.3 0.5 0.0056 17.3 0.5 1.7 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF2207 PF09972.9 KFM56537.1 - 0.071 11.9 0.2 0.083 11.6 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 KFM56537.1 - 0.12 13.3 3.5 0.29 12.1 2.5 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM132D_C PF15706.5 KFM56537.1 - 0.19 11.5 4.6 0.26 11.1 2.2 1.9 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ODV-E18 PF10717.9 KFM56537.1 - 0.35 10.8 0.1 0.35 10.8 0.1 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 CYYR1 PF10873.8 KFM56537.1 - 0.51 10.8 19.3 0.11 12.9 15.2 1.7 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF5326 PF17260.2 KFM56537.1 - 0.69 10.1 7.9 2.2 8.5 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5326) DUF3827 PF12877.7 KFM56537.1 - 0.96 7.7 6.5 1.6 7.0 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Podoplanin PF05808.11 KFM56537.1 - 1.9 8.5 7.9 2.9 8.0 7.9 1.2 1 0 0 1 1 1 0 Podoplanin Comm PF15957.5 KFM56537.1 - 3.3 8.1 8.9 7.5 6.9 8.9 1.6 1 1 0 1 1 1 0 Commissureless Xpo1 PF08389.12 KFM56538.1 - 5.2e-34 117.5 0.8 5.2e-34 117.5 0.8 4.4 5 1 0 5 5 5 1 Exportin 1-like protein HEAT_EZ PF13513.6 KFM56538.1 - 0.0085 16.6 0.0 0.67 10.5 0.0 3.3 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KFM56538.1 - 0.039 14.2 0.0 8.1 7.0 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Het-C PF07217.11 KFM56538.1 - 0.043 12.3 1.5 0.16 10.5 0.2 2.4 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C DUF3385 PF11865.8 KFM56538.1 - 0.052 13.5 0.3 0.22 11.4 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) MIT PF04212.18 KFM56538.1 - 0.082 13.0 0.3 0.62 10.2 0.0 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SSF PF00474.17 KFM56539.1 - 9.3e-93 311.3 17.0 1.4e-92 310.7 17.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family 7TM_GPCR_Sri PF10327.9 KFM56539.1 - 6.5e-05 22.3 3.3 6.5e-05 22.3 3.3 2.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Sri BIR PF00653.21 KFM56542.1 - 2e-23 82.8 2.5 2.6e-23 82.4 2.5 1.1 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 KFM56542.1 - 0.00057 19.9 0.4 0.0017 18.4 0.3 1.7 1 1 1 2 2 2 1 C3HC zinc finger-like Exo_endo_phos_2 PF14529.6 KFM56543.1 - 0.0012 18.6 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF5462 PF17547.2 KFM56544.1 - 0.024 14.0 1.2 6.6 6.1 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5462) F5_F8_type_C PF00754.25 KFM56545.1 - 6.1e-13 49.0 0.0 7.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Syntaxin_2 PF14523.6 KFM56547.1 - 0.0098 16.3 1.1 2.1 8.8 0.3 2.0 1 1 1 2 2 2 2 Syntaxin-like protein TcpS PF17456.2 KFM56547.1 - 0.02 14.9 0.3 0.023 14.7 0.3 1.1 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S PspA_IM30 PF04012.12 KFM56547.1 - 0.035 13.7 1.9 0.44 10.1 0.4 2.0 1 1 1 2 2 2 0 PspA/IM30 family PRKG1_interact PF15898.5 KFM56547.1 - 0.06 14.3 1.7 0.07 14.0 1.7 1.1 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain GTP-bdg_M PF16360.5 KFM56547.1 - 0.57 10.8 4.0 0.93 10.1 0.4 2.0 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region Phosphodiest PF01663.22 KFM56549.1 - 2e-73 248.0 0.0 3.9e-73 247.1 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Endonuclease_NS PF01223.23 KFM56549.1 - 2.3e-09 37.4 0.0 4.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.23 KFM56549.1 - 0.0027 17.1 0.0 0.0099 15.3 0.0 2.0 1 1 0 1 1 1 1 Sulfatase Acyl-CoA_dh_1 PF00441.24 KFM56550.1 - 1.6e-39 135.5 0.3 2.3e-39 135.0 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM56550.1 - 3.2e-28 98.6 0.0 5.7e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM56550.1 - 2e-19 69.6 0.0 3.5e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM56550.1 - 9.7e-16 58.3 0.1 1.5e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFM56550.1 - 0.051 13.2 0.0 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PdaC PF13739.6 KFM56550.1 - 0.11 13.4 0.1 0.24 12.4 0.1 1.5 1 0 0 1 1 1 0 Deacetylase PdaC HLH PF00010.26 KFM56552.1 - 2.6e-07 30.5 0.8 2.6e-07 30.5 0.8 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PCI PF01399.27 KFM56553.1 - 8.4e-27 93.7 2.2 8.4e-27 93.7 2.2 2.5 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 KFM56553.1 - 1.5e-06 27.8 2.7 1.4 9.1 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM56553.1 - 0.0036 17.3 0.9 21 5.6 0.1 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM56553.1 - 0.017 14.9 6.4 23 5.0 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM56553.1 - 0.56 9.9 2.5 60 3.4 0.4 4.1 4 0 0 4 4 4 0 TPR repeat LSM PF01423.22 KFM56554.1 - 8.7e-18 63.8 0.3 1.4e-17 63.1 0.3 1.3 1 0 0 1 1 1 1 LSM domain HTH_Tnp_Tc3_2 PF01498.18 KFM56555.1 - 5e-16 58.7 2.2 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM56555.1 - 1.1e-13 51.1 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ras PF00071.22 KFM56557.1 - 2.5e-13 50.0 0.2 2.7e-13 49.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM56557.1 - 0.00065 19.9 0.9 0.0045 17.2 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM56558.1 - 2.1e-20 73.0 0.0 3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM56558.1 - 0.023 14.9 0.1 0.049 13.8 0.1 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Av_adeno_fibre PF06536.11 KFM56558.1 - 0.17 11.8 0.7 14 5.6 0.1 2.3 2 0 0 2 2 2 0 Avian adenovirus fibre, N-terminal PDZ PF00595.24 KFM56561.1 - 1.7e-34 118.0 5.4 1.8e-16 60.3 0.4 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM56561.1 - 1.6e-21 75.9 0.7 2.1e-10 40.3 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFM56561.1 - 3e-12 46.7 0.7 1.1e-05 25.7 0.1 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 KFM56561.1 - 0.013 15.5 0.3 7.2 6.6 0.1 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain PDZ PF00595.24 KFM56562.1 - 2e-06 28.1 0.0 3.9e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM56562.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain FYRC PF05965.14 KFM56562.1 - 0.065 13.4 0.0 0.67 10.1 0.0 2.3 1 1 1 2 2 2 0 F/Y rich C-terminus WW PF00397.26 KFM56563.1 - 1.3e-17 63.6 6.2 2.3e-10 40.4 0.4 2.6 2 0 0 2 2 2 2 WW domain Guanylate_kin PF00625.21 KFM56563.1 - 1.6e-09 37.7 0.0 3.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ_2 PF13180.6 KFM56563.1 - 0.0048 17.2 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM56563.1 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM56563.1 - 0.016 15.5 0.1 0.049 14.0 0.1 1.8 1 0 0 1 1 1 0 PDZ domain Ring_hydroxyl_A PF00848.19 KFM56564.1 - 0.16 11.9 0.0 0.16 11.9 0.0 1.0 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Fringe PF02434.16 KFM56565.1 - 1.2e-48 165.7 0.0 1.4e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KFM56565.1 - 0.00029 20.7 0.0 0.00053 19.9 0.0 1.4 1 1 0 1 1 1 1 Galactosyltransferase HAP1_N PF04849.13 KFM56567.1 - 7.6e-09 35.2 0.5 7.6e-09 35.2 0.5 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region KIX PF02172.16 KFM56567.1 - 0.048 13.9 0.1 0.062 13.6 0.1 1.3 1 1 0 1 1 1 0 KIX domain NFRKB_winged PF14465.6 KFM56568.1 - 0.056 13.6 0.0 0.082 13.1 0.0 1.4 1 1 0 1 1 1 0 NFRKB Winged Helix-like RCC1 PF00415.18 KFM56569.1 - 9.2e-24 83.8 12.2 2.4e-07 31.3 0.0 4.5 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM56569.1 - 1.1e-16 60.2 7.3 2.9e-06 26.9 0.4 3.4 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KFM56569.1 - 0.038 14.5 0.3 11 6.5 0.0 3.0 1 1 1 3 3 3 0 SUKH-3 immunity protein MIB_HERC2 PF06701.13 KFM56574.1 - 5e-23 81.1 4.7 7.4e-23 80.6 4.7 1.3 1 0 0 1 1 1 1 Mib_herc2 Cul7 PF11515.8 KFM56577.1 - 3.3e-14 52.9 0.7 4.6e-14 52.5 0.7 1.2 1 0 0 1 1 1 1 Mouse development and cellular proliferation protein Cullin-7 RCC1 PF00415.18 KFM56578.1 - 3.1e-90 296.6 15.5 4.9e-14 52.7 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM56578.1 - 2.5e-41 138.7 32.6 1.5e-08 34.2 2.3 8.5 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat ANAPC10 PF03256.16 KFM56578.1 - 1.1e-08 34.9 0.0 2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) ZZ PF00569.17 KFM56578.1 - 1.1e-06 28.3 6.1 3.5e-06 26.7 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, ZZ type Prok-RING_2 PF14445.6 KFM56578.1 - 0.084 13.1 0.8 0.29 11.3 0.8 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 PapC_C PF13953.6 KFM56578.1 - 0.1 12.4 0.2 5.5 6.9 0.0 3.0 3 0 0 3 3 3 0 PapC C-terminal domain RCC1 PF00415.18 KFM56579.1 - 0.00049 20.7 0.3 0.00049 20.7 0.3 2.1 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Phe_tRNA-synt_N PF02912.18 KFM56579.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain I-set PF07679.16 KFM56580.1 - 1.2e-18 66.9 0.1 1.6e-11 44.1 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM56580.1 - 4.8e-15 55.9 0.1 1.4e-08 35.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM56580.1 - 3.4e-11 43.2 0.0 1.4e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM56580.1 - 2.4e-08 34.2 0.1 8.8e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM56580.1 - 0.00045 20.2 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM56580.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM56580.1 - 0.0028 17.8 0.0 0.2 11.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM56580.1 - 0.025 14.9 0.3 0.16 12.4 0.3 2.2 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set_CD47 PF08204.11 KFM56580.1 - 0.026 14.5 0.1 0.058 13.4 0.0 1.6 1 1 1 2 2 2 0 CD47 immunoglobulin-like domain C2-set PF05790.15 KFM56580.1 - 0.055 13.7 0.0 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Prok-E2_C PF14459.6 KFM56580.1 - 0.075 13.2 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family C Izumo-Ig PF16706.5 KFM56580.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 KFM56581.1 - 3.1e-19 69.3 0.3 7.2e-11 42.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM56581.1 - 5e-19 68.2 0.1 1.1e-11 44.6 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM56581.1 - 3.2e-14 52.9 0.0 9.8e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM56581.1 - 1.4e-12 47.8 0.0 4.2e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM56581.1 - 2.6e-06 27.4 0.2 0.0038 17.3 0.0 2.7 2 1 1 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM56581.1 - 3.6e-06 27.3 0.0 0.00071 19.9 0.0 2.4 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFM56581.1 - 0.00016 21.7 0.1 0.0011 19.0 0.1 2.0 2 0 0 2 2 2 1 C17orf99 Ig domain V-set PF07686.17 KFM56581.1 - 0.001 19.2 0.1 1.9 8.7 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain V-set_CD47 PF08204.11 KFM56581.1 - 0.0083 16.1 0.2 0.024 14.6 0.2 1.8 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Ig_6 PF18452.1 KFM56581.1 - 0.0092 15.5 0.0 0.02 14.5 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 KFM56581.1 - 0.016 15.4 0.0 0.42 10.9 0.0 2.6 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain fn3 PF00041.21 KFM56583.1 - 2.6e-50 168.7 10.1 1.9e-17 63.3 0.1 3.8 4 0 0 4 4 4 3 Fibronectin type III domain I-set PF07679.16 KFM56583.1 - 1.5e-15 57.0 2.5 2.1e-14 53.3 0.0 3.4 4 0 0 4 4 4 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM56583.1 - 2.1e-09 37.9 4.4 8.3e-09 35.9 0.0 3.8 4 1 1 5 5 5 1 Immunoglobulin domain Ig_2 PF13895.6 KFM56583.1 - 3e-07 30.7 0.0 7.2e-06 26.3 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 KFM56583.1 - 1.2e-06 28.6 0.0 3.8e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Interfer-bind PF09294.10 KFM56583.1 - 7.1e-06 26.3 0.0 0.044 14.1 0.0 3.3 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KFM56583.1 - 5.5e-05 23.7 8.6 0.42 11.2 0.0 4.4 4 2 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KFM56583.1 - 0.016 15.1 0.1 0.79 9.6 0.1 2.5 2 0 0 2 2 2 0 Tissue factor DUF2369 PF10179.9 KFM56583.1 - 0.099 13.0 0.0 19 5.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 KFM56583.1 - 0.11 12.5 0.0 1.1 9.2 0.0 2.8 3 1 0 3 3 3 0 Fibronectin-III type domain CREPT PF16566.5 KFM56584.1 - 0.018 15.2 0.2 0.018 15.2 0.2 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4939 PF16297.5 KFM56584.1 - 0.079 12.8 0.2 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) DUF4371 PF14291.6 KFM56585.1 - 0.0012 18.6 0.4 0.0012 18.6 0.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Poty_PP PF08440.10 KFM56585.1 - 0.076 12.1 0.9 0.1 11.7 0.2 1.6 2 0 0 2 2 2 0 Potyviridae polyprotein CRAL_TRIO_N PF03765.15 KFM56586.1 - 2e-06 27.9 0.4 2.9e-06 27.4 0.4 1.5 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CUE PF02845.16 KFM56586.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 CUE domain ADK PF00406.22 KFM56587.1 - 1.3e-61 207.1 0.0 1.6e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFM56587.1 - 1e-22 81.0 0.1 1.9e-22 80.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KFM56587.1 - 1.8e-15 56.6 0.0 4.3e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 KFM56587.1 - 0.01 16.0 0.0 0.057 13.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFM56587.1 - 0.011 16.3 0.1 0.059 13.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain CPL PF08144.11 KFM56588.1 - 2.6e-12 47.3 0.0 2.7e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 CPL (NUC119) domain DUF1344 PF07076.11 KFM56589.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) APC_basic PF05956.11 KFM56589.1 - 0.17 11.3 9.5 0.22 11.0 9.5 1.1 1 0 0 1 1 1 0 APC basic domain IBR PF01485.21 KFM56590.1 - 8.7e-21 73.9 50.5 3.1e-14 52.9 8.9 5.1 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KFM56590.1 - 2.5e-06 27.2 3.1 2.5e-06 27.2 3.1 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM56590.1 - 0.00025 21.3 7.3 0.00025 21.3 7.3 4.8 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KFM56590.1 - 0.0021 17.9 7.5 0.0021 17.9 7.5 5.0 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM56590.1 - 0.0024 17.9 3.5 0.0024 17.9 3.5 4.4 4 0 0 4 4 4 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM56590.1 - 3.1 8.0 32.6 0.061 13.5 2.1 4.8 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFM56590.1 - 5.7 6.8 16.2 0.73 9.6 4.6 3.7 3 0 0 3 3 3 0 RING-like zinc finger Ribosomal_L24e PF01246.20 KFM56591.1 - 1.4e-32 111.7 2.2 1.4e-32 111.7 2.2 2.0 2 1 1 3 3 3 1 Ribosomal protein L24e LRR_4 PF12799.7 KFM56592.1 - 1.4e-12 47.6 19.6 1.6e-06 28.3 4.4 3.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM56592.1 - 3.2e-12 46.3 0.8 4e-12 46.0 0.8 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KFM56592.1 - 3e-11 42.9 18.0 1.7e-07 30.8 8.4 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KFM56592.1 - 7.1e-05 22.5 15.1 0.99 9.6 0.3 5.3 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 KFM56592.1 - 0.017 15.6 18.9 1 10.2 0.2 5.1 4 2 0 4 4 4 0 Leucine Rich Repeat F5_F8_type_C PF00754.25 KFM56595.1 - 1.1e-05 25.6 0.0 1.3e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 KFM56595.1 - 0.00027 20.7 0.1 0.00029 20.5 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) RA PF00788.23 KFM56597.1 - 5.6e-13 49.3 0.2 1.6e-12 47.8 0.2 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 KFM56597.1 - 4.4e-12 45.7 6.9 4.4e-12 45.7 6.9 2.5 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain C1_1 PF00130.22 KFM56597.1 - 1.9e-11 43.7 15.1 3.1e-11 43.0 15.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ras_bdg_2 PF14847.6 KFM56597.1 - 0.00027 21.2 0.0 0.00054 20.3 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Plexin_cytopl PF08337.12 KFM56598.1 - 3.2e-256 851.3 2.1 4.1e-256 851.0 2.1 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFM56598.1 - 2.6e-31 107.5 2.9 2.9e-08 33.7 0.1 4.7 4 0 0 4 4 4 4 IPT/TIG domain TIG_2 PF18020.1 KFM56598.1 - 6.9e-23 81.1 0.1 2.2e-19 69.9 0.1 3.8 4 0 0 4 4 4 1 TIG domain found in plexin TIG_plexin PF17960.1 KFM56598.1 - 1.1e-21 76.6 4.2 1.1e-20 73.4 0.1 3.8 4 0 0 4 4 4 1 TIG domain PSI PF01437.25 KFM56598.1 - 1.2e-20 73.8 47.7 7.8e-10 39.1 9.6 3.7 3 0 0 3 3 3 3 Plexin repeat EphA2_TM PF14575.6 KFM56598.1 - 0.039 14.8 0.1 0.091 13.7 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KFM56598.1 - 0.1 12.5 0.3 0.3 11.0 0.3 1.7 1 0 0 1 1 1 0 Syndecan domain PSI_integrin PF17205.3 KFM56598.1 - 6.5 6.6 47.4 1.7 8.5 9.0 3.8 3 0 0 3 3 3 0 Integrin plexin domain Peptidase_M1 PF01433.20 KFM56599.1 - 5.4e-83 277.9 0.1 7.9e-83 277.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFM56599.1 - 3.8e-54 183.7 0.0 5.4e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KFM56599.1 - 0.081 13.3 1.4 1.9 8.9 1.5 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Aminopep PF10023.9 KFM56599.1 - 0.088 12.2 0.2 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Putative aminopeptidase ALS2CR8 PF15299.6 KFM56602.1 - 2e-05 24.6 0.2 2.4e-05 24.3 0.2 1.0 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Myb_DNA-bind_4 PF13837.6 KFM56603.1 - 5e-10 39.6 1.2 5e-10 39.6 1.2 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM56603.1 - 3.5e-06 27.2 0.5 1.1e-05 25.7 0.3 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like SLT_L PF14718.6 KFM56603.1 - 0.016 15.3 0.3 0.42 10.8 0.2 2.4 1 1 1 2 2 2 0 Soluble lytic murein transglycosylase L domain SlyX PF04102.12 KFM56603.1 - 0.032 14.9 3.3 6.2 7.5 0.0 2.5 2 0 0 2 2 2 0 SlyX DUF573 PF04504.14 KFM56603.1 - 0.05 14.3 0.6 0.15 12.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF573 Dynactin_p22 PF07426.11 KFM56603.1 - 0.092 12.6 2.6 0.37 10.6 2.5 1.9 1 1 1 2 2 2 0 Dynactin subunit p22 RRM_1 PF00076.22 KFM56604.1 - 2.6e-49 164.9 0.2 7.4e-16 57.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM56604.1 - 1.6e-10 40.7 0.0 0.00033 20.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM56604.1 - 5.7e-07 29.3 0.0 0.28 11.1 0.0 3.3 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_3 PF08777.11 KFM56604.1 - 0.00012 22.1 2.3 0.16 12.0 0.0 3.6 4 0 0 4 4 4 2 RNA binding motif Limkain-b1 PF11608.8 KFM56604.1 - 0.026 14.6 0.4 0.13 12.3 0.0 2.4 3 1 0 3 3 3 0 Limkain b1 TED_complement PF07678.14 KFM56606.1 - 3.8e-89 298.8 0.0 5.9e-89 298.2 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 KFM56606.1 - 1.9e-24 85.3 0.1 6e-24 83.7 0.1 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFM56606.1 - 1.6e-23 83.2 0.4 4.9e-23 81.6 0.4 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain A2M_BRD PF07703.14 KFM56606.1 - 3.3e-14 53.4 0.0 1.2e-13 51.6 0.0 2.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain SVA PF05326.11 KFM56606.1 - 2.8e-05 24.1 0.2 0.00014 21.9 0.0 2.3 2 0 0 2 2 2 1 Seminal vesicle autoantigen (SVA) Pkinase PF00069.25 KFM56607.1 - 3.2e-48 164.4 0.0 3.5e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM56607.1 - 6.6e-25 87.9 0.0 7.3e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM56607.1 - 9.4e-05 21.4 0.1 0.00015 20.7 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFM56607.1 - 0.00032 20.1 0.1 0.00038 19.9 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM56607.1 - 0.00054 19.4 0.0 0.00056 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFM56607.1 - 0.028 14.0 0.1 0.033 13.8 0.1 1.1 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KFM56607.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KFM56607.1 - 0.19 11.6 0.1 3.2 7.6 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Retrotran_gag_2 PF14223.6 KFM56610.1 - 3.3e-19 68.9 1.0 3.7e-19 68.8 1.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MOLO1 PF17175.4 KFM56610.1 - 0.026 14.6 0.2 0.064 13.4 0.1 1.7 1 1 0 1 1 1 0 Modulator of levamisole receptor-1 Imm44 PF15571.6 KFM56610.1 - 0.05 13.9 0.1 0.062 13.6 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 44 Dynamin_M PF01031.20 KFM56611.1 - 8.3e-102 340.2 0.4 2e-101 339.0 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KFM56611.1 - 8.4e-54 182.1 0.1 2.7e-53 180.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KFM56611.1 - 5e-32 109.9 3.7 1.4e-31 108.5 3.7 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFM56611.1 - 2.5e-05 24.3 0.0 9.3e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFM56611.1 - 0.011 16.1 0.0 0.071 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 KFM56611.1 - 0.019 14.7 0.3 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DDE_3 PF13358.6 KFM56612.1 - 0.022 14.5 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease RB_A PF01858.17 KFM56613.1 - 1.6e-24 86.9 0.1 1.8e-24 86.7 0.1 1.0 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain Myco_arth_vir_N PF09610.10 KFM56613.1 - 0.51 10.5 1.1 1.1 9.4 1.1 1.6 1 1 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF3452 PF11934.8 KFM56614.1 - 4.1e-15 55.5 1.2 5.9e-15 55.0 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) CPSase_L_D2 PF02786.17 KFM56616.1 - 2.1e-77 259.4 0.0 7.7e-77 257.5 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFM56616.1 - 1.3e-46 157.7 0.6 7e-44 148.9 0.1 2.4 2 0 0 2 2 2 2 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFM56616.1 - 9e-39 131.9 0.0 2.7e-37 127.1 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFM56616.1 - 6.7e-14 51.5 6.7 1.1e-12 47.6 5.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFM56616.1 - 9.6e-13 48.1 0.0 2.5e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFM56616.1 - 6e-11 42.2 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFM56616.1 - 3.5e-06 27.2 0.2 8.9e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KFM56616.1 - 5.4e-06 26.1 0.0 6.6e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 KFM56616.1 - 0.00016 21.1 0.0 0.062 12.5 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 KFM56616.1 - 0.00018 22.2 0.5 0.41 11.4 0.2 3.1 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 KFM56616.1 - 0.0016 17.7 0.3 1.5 8.0 0.1 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 KFM56616.1 - 0.005 16.6 5.6 0.0063 16.3 0.2 2.9 3 0 0 3 3 3 1 Biotin-lipoyl like ATP-grasp_4 PF13535.6 KFM56616.1 - 0.0098 15.5 0.1 0.15 11.7 0.0 2.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KFM56616.1 - 0.011 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ntox43 PF15537.6 KFM56616.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 43 DUF3182 PF11379.8 KFM56616.1 - 0.036 13.0 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Peptidase_C54 PF03416.19 KFM56617.1 - 6e-94 314.5 0.4 7.2e-94 314.3 0.4 1.0 1 0 0 1 1 1 1 Peptidase family C54 Sec34 PF04136.15 KFM56619.1 - 2.4e-46 157.3 6.2 3.9e-46 156.6 3.1 2.6 2 0 0 2 2 2 1 Sec34-like family YycI PF09648.10 KFM56619.1 - 0.015 14.9 2.2 0.16 11.5 0.0 2.9 3 0 0 3 3 3 0 YycH protein SKA2 PF16740.5 KFM56619.1 - 0.068 13.0 0.8 0.58 9.9 0.1 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 CPG4 PF15481.6 KFM56619.1 - 9.7 6.9 7.0 3.3 8.4 0.1 3.5 3 1 1 4 4 4 0 Chondroitin proteoglycan 4 Ax_dynein_light PF10211.9 KFM56620.1 - 0.11 12.4 12.8 0.12 12.3 12.8 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain LapA_dom PF06305.11 KFM56621.1 - 0.0024 17.6 0.3 0.0029 17.4 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 KFM56621.1 - 0.012 16.5 0.0 0.013 16.4 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 KFM56621.1 - 0.02 14.7 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 TMIE protein Mid2 PF04478.12 KFM56621.1 - 0.023 14.5 0.1 0.025 14.4 0.1 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TraL PF07178.11 KFM56621.1 - 0.035 14.6 0.1 0.038 14.5 0.1 1.0 1 0 0 1 1 1 0 TraL protein HisKA_4TM PF16926.5 KFM56621.1 - 0.074 12.6 0.2 0.087 12.4 0.2 1.1 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase DUF3948 PF13134.6 KFM56621.1 - 0.13 12.0 1.5 0.21 11.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) stn_TNFRSF12A PF12191.8 KFM56621.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF1286 PF06939.11 KFM56622.1 - 0.015 15.6 0.9 0.017 15.4 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1286) DEAD PF00270.29 KFM56623.1 - 7.4e-51 172.4 0.0 2e-50 171.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM56623.1 - 8.2e-26 90.5 0.0 1.5e-24 86.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CdAMP_rec PF06153.11 KFM56623.1 - 0.062 13.5 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Cyclic-di-AMP receptor HTH_Tnp_Tc3_2 PF01498.18 KFM56624.1 - 2.7e-16 59.5 2.2 6.8e-16 58.3 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM56624.1 - 1.1e-13 51.2 0.0 2.8e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Glyco_hydro_47 PF01532.20 KFM56624.1 - 0.11 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 HTH_Tnp_Tc5 PF03221.16 KFM56625.1 - 5.8e-11 42.3 0.5 9.3e-11 41.6 0.5 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3372 PF11852.8 KFM56625.1 - 0.068 12.6 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) cNMP_binding PF00027.29 KFM56626.1 - 2.7e-09 37.0 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RasGEF PF00617.19 KFM56627.1 - 6e-49 166.6 0.9 1e-48 165.9 0.9 1.4 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.29 KFM56627.1 - 2.1e-16 59.8 0.0 6e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RasGEF_N PF00618.20 KFM56627.1 - 1.4e-15 57.4 0.2 3.4e-15 56.2 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DEP PF00610.21 KFM56627.1 - 8.8e-15 54.5 1.8 1.1e-13 51.0 0.4 2.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Tubulin PF00091.25 KFM56629.1 - 3.4e-69 233.0 0.0 5.3e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM56629.1 - 1.5e-43 148.0 0.1 2.4e-43 147.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFM56629.1 - 7.5e-05 23.0 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KFM56629.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFM56629.1 - 0.0096 15.1 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Glyco_hydro_85 PF03644.13 KFM56630.1 - 1.4e-92 310.3 0.5 1.9e-92 309.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 MCD PF05292.11 KFM56631.1 - 5.3e-30 104.9 0.1 6.6e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain SIX1_SD PF16878.5 KFM56631.1 - 0.057 13.9 0.4 0.1 13.1 0.1 1.6 2 0 0 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain GIDA_assoc PF13932.6 KFM56631.1 - 0.064 13.4 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 GidA associated domain MCD PF05292.11 KFM56632.1 - 1.1e-55 188.9 0.1 1.5e-55 188.6 0.1 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain TIP49 PF06068.13 KFM56632.1 - 0.03 13.5 0.2 0.039 13.2 0.2 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain ATE_C PF04377.15 KFM56633.1 - 1.1e-50 171.7 7.1 2.6e-50 170.5 7.1 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KFM56633.1 - 3.2e-27 94.7 10.1 3.2e-27 94.7 10.1 2.4 3 0 0 3 3 3 1 Arginine-tRNA-protein transferase, N terminus Nre_N PF04894.12 KFM56634.1 - 0.21 11.4 1.9 1.7 8.4 0.7 2.0 1 1 1 2 2 2 0 Archaeal Nre, N-terminal PET117 PF15786.5 KFM56634.1 - 2.4 8.5 15.8 0.13 12.5 4.4 2.9 2 1 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Tropomyosin PF00261.20 KFM56635.1 - 2e-101 338.3 79.6 2.4e-92 308.6 56.9 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFM56635.1 - 1.2e-37 129.2 68.6 5.7e-34 117.3 35.3 3.0 1 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 KFM56635.1 - 5.5e-10 39.4 35.8 3.4e-05 23.9 13.1 3.4 1 1 1 3 3 3 3 Laminin Domain II DUF745 PF05335.13 KFM56635.1 - 9.9e-05 22.1 49.6 0.00071 19.4 20.5 3.2 1 1 1 3 3 3 2 Protein of unknown function (DUF745) CLZ PF16526.5 KFM56635.1 - 0.00057 20.2 9.7 0.00057 20.2 9.7 5.4 1 1 4 5 5 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KFM56635.1 - 0.00057 19.9 31.3 0.018 15.0 5.5 3.8 1 1 3 5 5 5 3 Protein of unknown function (DUF1664) MscS_porin PF12795.7 KFM56635.1 - 0.00062 19.4 23.6 0.00062 19.4 23.6 3.0 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain Uds1 PF15456.6 KFM56635.1 - 0.00076 19.6 45.6 0.19 11.9 7.3 3.3 1 1 2 3 3 3 3 Up-regulated During Septation FPP PF05911.11 KFM56635.1 - 0.001 17.4 51.7 0.024 12.8 27.4 2.2 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 KFM56635.1 - 0.0021 18.3 61.4 0.098 12.9 21.7 3.1 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KFM56635.1 - 0.0064 16.6 64.4 0.043 13.9 21.2 3.8 1 1 3 4 4 4 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KFM56635.1 - 0.0066 16.9 50.9 0.16 12.4 23.5 2.4 1 1 1 2 2 2 2 Fez1 Fib_alpha PF08702.10 KFM56635.1 - 0.011 15.9 29.2 0.63 10.2 6.1 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 KFM56635.1 - 0.013 15.5 64.0 0.095 12.7 31.0 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_I PF06008.14 KFM56635.1 - 0.013 15.2 14.3 0.013 15.2 14.3 4.1 1 1 3 4 4 4 0 Laminin Domain I HrpB7 PF09486.10 KFM56635.1 - 0.029 14.8 57.5 0.1 13.0 15.8 4.1 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) EzrA PF06160.12 KFM56635.1 - 0.03 12.5 46.6 0.24 9.5 5.9 3.2 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA AAA_13 PF13166.6 KFM56635.1 - 0.031 12.9 47.5 0.23 10.1 27.9 2.5 1 1 0 2 2 2 0 AAA domain HemX PF04375.14 KFM56635.1 - 0.12 11.6 44.4 0.54 9.5 20.3 3.0 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spc7 PF08317.11 KFM56635.1 - 0.15 10.9 60.6 0.49 9.2 26.9 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein Fusion_gly PF00523.18 KFM56635.1 - 0.17 10.1 3.7 0.15 10.3 1.2 2.1 1 1 0 2 2 2 0 Fusion glycoprotein F0 DUF1794 PF08768.11 KFM56635.1 - 0.33 10.9 8.0 21 5.0 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1794) DHR10 PF18595.1 KFM56635.1 - 0.4 10.7 69.1 0.25 11.4 15.6 4.5 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 KFM56635.1 - 0.44 11.0 21.6 2 9.0 7.5 4.7 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 KFM56635.1 - 0.54 9.5 51.9 0.13 11.6 16.2 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) PhaC_N PF07167.13 KFM56635.1 - 0.63 9.7 5.4 0.34 10.5 0.5 2.6 1 1 1 3 3 3 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Exonuc_VII_L PF02601.15 KFM56635.1 - 0.66 9.5 40.4 1.7 8.2 17.7 2.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit Lebercilin PF15619.6 KFM56635.1 - 0.99 9.0 62.2 0.48 10.1 17.6 3.5 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 KFM56635.1 - 1 8.8 57.8 0.92 8.9 19.5 2.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF16 PF01519.16 KFM56635.1 - 1.1 9.7 40.2 0.59 10.7 3.5 4.1 1 1 3 4 4 4 0 Protein of unknown function DUF16 DUF4200 PF13863.6 KFM56635.1 - 1.4 9.3 69.4 0.16 12.3 14.3 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) Sec34 PF04136.15 KFM56635.1 - 1.7 8.5 25.0 0.92 9.4 6.8 3.2 1 1 1 3 3 3 0 Sec34-like family Vps5 PF09325.10 KFM56635.1 - 1.8 8.0 43.6 0.45 10.0 8.0 4.5 1 1 2 4 4 4 0 Vps5 C terminal like ERM PF00769.19 KFM56635.1 - 1.8 8.3 75.9 0.17 11.7 28.2 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family DUF724 PF05266.14 KFM56635.1 - 2.1 8.1 51.6 0.41 10.5 14.8 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF724) DUF3037 PF11236.8 KFM56635.1 - 2.5 8.5 22.9 9 6.8 3.2 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) DUF948 PF06103.11 KFM56635.1 - 2.9 8.2 17.2 15 5.9 0.2 4.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 KFM56635.1 - 3.7 7.8 47.6 0.67 10.2 1.7 6.3 1 1 6 8 8 8 0 Haemolysin XhlA Allexi_40kDa PF05549.11 KFM56635.1 - 4 6.9 20.2 3.3 7.1 6.8 2.8 1 1 2 3 3 3 0 Allexivirus 40kDa protein FH2 PF02181.23 KFM56635.1 - 4.2 6.4 32.2 0.78 8.8 6.2 3.1 1 1 2 3 3 3 0 Formin Homology 2 Domain Atg14 PF10186.9 KFM56635.1 - 4.6 6.2 48.2 0.46 9.5 11.9 3.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spectrin PF00435.21 KFM56635.1 - 4.6 7.8 43.8 1 9.9 5.2 4.7 1 1 3 4 4 4 0 Spectrin repeat FOXP-CC PF16159.5 KFM56635.1 - 5.2 7.8 21.3 2.3 8.9 0.9 4.3 2 2 3 5 5 4 0 FOXP coiled-coil domain IFT57 PF10498.9 KFM56635.1 - 6.3 5.7 41.9 0.9 8.4 10.6 3.2 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 WXG100 PF06013.12 KFM56635.1 - 6.6 7.0 23.3 0.17 12.1 3.3 4.6 2 2 1 4 4 4 0 Proteins of 100 residues with WXG SOGA PF11365.8 KFM56635.1 - 7.7 7.7 45.2 0.62 11.2 10.2 4.4 1 1 4 5 5 5 0 Protein SOGA HMMR_N PF15905.5 KFM56635.1 - 8.6 5.7 55.2 4.5 6.6 22.2 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 KFM56635.1 - 9.3 4.5 58.8 9.4 4.5 25.8 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein SNARE PF05739.19 KFM56635.1 - 10 6.2 20.0 3.8 7.6 1.1 5.0 4 1 0 5 5 5 0 SNARE domain IRS PF02174.17 KFM56637.1 - 6.6e-21 74.1 0.0 1.4e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) HLH PF00010.26 KFM56638.1 - 1.5e-16 60.0 3.9 2.1e-16 59.6 3.9 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Alk_phosphatase PF00245.20 KFM56639.1 - 2.1e-134 448.6 0.3 2.4e-134 448.4 0.3 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KFM56639.1 - 0.00033 20.1 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KFM56639.1 - 0.0014 18.3 0.1 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Phostensin PF13914.6 KFM56640.1 - 0.00033 21.3 0.0 0.00033 21.3 0.0 2.6 3 0 0 3 3 3 1 Phostensin PP1-binding and SH3-binding region ACT_6 PF13740.6 KFM56641.1 - 0.016 15.2 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 ACT domain Ig_2 PF13895.6 KFM56642.1 - 3.2e-13 49.8 1.5 4.3e-05 23.8 0.2 3.5 2 2 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.6 KFM56642.1 - 4.2e-13 49.7 0.5 1.4e-06 28.8 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFM56642.1 - 7.2e-09 35.7 0.3 0.00056 20.0 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM56642.1 - 1.4e-07 31.6 0.0 2.5e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM56642.1 - 3.7e-06 26.9 0.1 3.1e-05 24.0 0.1 2.6 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM56642.1 - 0.005 17.2 0.0 1.8 9.1 0.0 3.0 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF2244 PF10003.9 KFM56642.1 - 0.12 12.0 0.9 0.71 9.5 0.6 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF3681 PF12442.8 KFM56643.1 - 0.1 13.1 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) zf-C3HC4_2 PF13923.6 KFM56645.1 - 4.9e-10 39.1 9.4 4.9e-10 39.1 9.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM56645.1 - 1.9e-09 37.2 10.5 1.9e-09 37.2 10.5 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM56645.1 - 1.6e-06 27.9 8.0 3.7e-06 26.7 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM56645.1 - 4.2e-06 26.6 10.9 4.6e-06 26.5 4.7 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFM56645.1 - 1.3e-05 25.4 15.8 1.4e-05 25.3 9.9 3.0 2 1 1 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 KFM56645.1 - 0.00012 22.2 8.1 0.00012 22.2 8.1 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM56645.1 - 0.00017 21.5 6.1 0.00017 21.5 6.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM56645.1 - 0.00062 19.6 6.3 0.0009 19.1 5.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 RAWUL PF16207.5 KFM56645.1 - 0.012 16.2 1.5 0.035 14.8 0.2 2.1 2 0 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_10 PF16685.5 KFM56645.1 - 0.013 15.6 5.1 0.034 14.3 5.1 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KFM56645.1 - 0.016 15.4 11.6 0.026 14.7 10.4 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFM56645.1 - 0.02 14.7 7.4 0.04 13.8 7.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KFM56645.1 - 0.023 14.6 3.2 0.066 13.1 2.3 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KFM56645.1 - 0.023 14.7 2.4 0.023 14.7 2.4 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pkinase PF00069.25 KFM56647.1 - 1.1e-17 64.3 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM56647.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Varsurf_PPLC PF03490.13 KFM56648.1 - 0.092 12.7 0.8 0.092 12.7 0.8 2.6 1 1 2 3 3 3 0 Variant-surface-glycoprotein phospholipase C Cyclin_N PF00134.23 KFM56649.1 - 3.9e-50 168.9 0.2 6.9e-50 168.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFM56649.1 - 2.3e-24 85.8 0.4 4.8e-24 84.7 0.4 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cytochrom_B561 PF03188.16 KFM56650.1 - 1.3e-42 145.1 7.2 1.3e-42 145.1 7.2 2.3 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Ferric_reduct PF01794.19 KFM56650.1 - 0.00015 21.9 3.6 0.00015 21.9 3.6 3.1 2 1 1 3 3 3 2 Ferric reductase like transmembrane component DUF2976 PF11190.8 KFM56650.1 - 4.3 7.2 6.1 21 5.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DivIC PF04977.15 KFM56651.1 - 4.9 7.0 7.9 0.77 9.6 2.7 2.3 1 1 1 2 2 2 0 Septum formation initiator FAD_binding_1 PF00667.20 KFM56652.1 - 1.2e-41 142.8 0.0 1.8e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFM56652.1 - 4e-33 114.6 0.0 7.5e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFM56652.1 - 6.7e-14 52.4 0.0 1.7e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 KFM56652.1 - 0.0057 16.4 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_5 PF12724.7 KFM56652.1 - 0.11 12.8 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain zf-H2C2_2 PF13465.6 KFM56653.1 - 1.1e-86 281.7 123.4 1.1e-07 31.9 0.1 16.1 16 0 0 16 16 16 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM56653.1 - 2e-64 210.6 144.7 1.3e-06 28.5 2.0 15.4 15 1 0 15 15 15 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM56653.1 - 6.1e-53 172.9 132.8 0.00013 22.5 1.2 15.2 15 0 0 15 15 15 15 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM56653.1 - 2.6e-15 56.0 112.0 0.029 14.4 0.6 15.7 15 0 0 15 15 15 9 C2H2-type zinc finger zf-met PF12874.7 KFM56653.1 - 2.7e-14 53.0 115.1 0.0011 19.3 1.9 15.2 15 0 0 15 15 15 8 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM56653.1 - 2e-11 43.4 107.8 0.43 10.4 0.6 16.2 16 1 0 16 16 16 10 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM56653.1 - 1.5e-10 41.1 95.2 0.0043 17.3 0.3 15.6 12 1 2 15 15 15 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM56653.1 - 5.3e-06 26.6 22.3 1.9 8.8 0.3 9.3 2 2 4 6 6 6 1 BolA-like protein GAGA PF09237.11 KFM56653.1 - 0.00052 19.8 25.6 0.39 10.6 0.4 8.1 2 2 7 9 9 9 2 GAGA factor zf-C2H2_11 PF16622.5 KFM56653.1 - 0.0016 18.2 0.1 0.0016 18.2 0.1 13.5 15 0 0 15 15 14 6 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM56653.1 - 0.067 13.1 64.8 3.5 7.6 0.4 13.0 14 0 0 14 14 13 0 zinc-finger of a C2HC-type GATase_2 PF00310.21 KFM56653.1 - 0.095 11.4 0.1 0.23 10.1 0.1 1.6 1 1 0 1 1 1 0 Glutamine amidotransferases class-II CTV_P23 PF04808.12 KFM56653.1 - 0.18 11.3 6.5 1.2 8.7 0.1 3.9 2 2 3 5 5 5 0 Citrus tristeza virus (CTV) P23 protein DrsE PF02635.15 KFM56653.1 - 0.18 12.2 2.2 6.6 7.1 0.2 3.8 3 1 1 4 4 4 0 DsrE/DsrF-like family zf-C2H2_2 PF12756.7 KFM56653.1 - 0.32 11.3 101.7 2.4 8.5 0.5 13.4 1 1 11 13 13 13 0 C2H2 type zinc-finger (2 copies) Baculo_IE-1 PF05290.11 KFM56653.1 - 1.4 8.9 47.3 0.25 11.3 0.9 8.6 1 1 3 6 6 6 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 KFM56653.1 - 2.3 8.4 89.9 6.2 7.0 3.7 9.0 1 1 2 4 4 3 0 FYVE zinc finger BHD_1 PF10403.9 KFM56653.1 - 2.7 7.9 5.9 5.3 7.0 0.0 4.5 5 3 0 5 5 5 0 Rad4 beta-hairpin domain 1 zf-C2H2_3rep PF18868.1 KFM56653.1 - 7 7.3 55.7 7.5 7.2 4.4 10.1 3 3 6 9 9 9 0 Zinc finger C2H2-type, 3 repeats zf-MYST PF17772.1 KFM56653.1 - 8.7 6.0 60.2 2.8 7.6 0.4 12.4 7 5 7 14 14 14 0 MYST family zinc finger domain Hormone_recep PF00104.30 KFM56655.1 - 7.4e-17 61.6 0.0 8.2e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TRAP_beta PF05753.14 KFM56656.1 - 1.8e-36 125.2 0.0 2.1e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) BatD PF13584.6 KFM56656.1 - 0.042 12.6 0.6 0.24 10.1 0.1 1.8 1 1 1 2 2 2 0 Oxygen tolerance WD40 PF00400.32 KFM56657.1 - 3.1e-34 116.4 30.5 2.2e-06 28.3 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.12 KFM56657.1 - 2.1e-16 60.2 0.4 3.7e-16 59.4 0.4 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 KFM56657.1 - 0.00017 21.9 2.9 0.21 11.9 0.1 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM56657.1 - 0.16 11.3 0.3 7.9 5.7 0.1 2.7 3 0 0 3 3 3 0 WD40-like domain DUF3523 PF12037.8 KFM56658.1 - 9.9e-102 339.8 26.9 1.3e-101 339.5 26.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 KFM56658.1 - 1.4e-14 54.6 0.0 3.9e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM56658.1 - 2.1e-06 28.2 4.3 0.0002 21.8 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KFM56658.1 - 5.4e-05 23.0 0.0 0.0008 19.2 0.0 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFM56658.1 - 0.00029 20.8 1.8 0.0017 18.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFM56658.1 - 0.0022 18.2 0.0 0.0022 18.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 KFM56658.1 - 0.0024 17.9 0.5 0.0063 16.5 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KFM56658.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 3.3 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KFM56658.1 - 0.0033 17.2 0.9 0.005 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFM56658.1 - 0.0066 15.8 1.8 0.0086 15.5 0.1 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFM56658.1 - 0.013 15.8 0.0 0.041 14.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KFM56658.1 - 0.023 14.2 0.5 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFM56658.1 - 0.035 14.7 0.0 0.035 14.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFM56658.1 - 0.037 14.3 0.0 0.037 14.3 0.0 3.0 3 1 0 3 3 2 0 AAA domain NACHT PF05729.12 KFM56658.1 - 0.04 13.8 0.2 0.13 12.2 0.0 2.0 2 1 1 3 3 3 0 NACHT domain AAA_28 PF13521.6 KFM56658.1 - 0.046 14.0 0.0 0.046 14.0 0.0 3.0 2 1 1 3 3 2 0 AAA domain AAA_3 PF07726.11 KFM56658.1 - 0.069 13.0 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFM56658.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 KFM56658.1 - 0.23 11.2 0.0 0.23 11.2 0.0 2.8 2 1 0 2 2 1 0 AAA domain SRPRB PF09439.10 KFM56658.1 - 0.95 8.9 8.9 9.7 5.6 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit PrkA PF06798.12 KFM56659.1 - 0.028 14.0 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain AAA_lid_3 PF17862.1 KFM56659.1 - 0.03 14.1 0.0 0.06 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA+ lid domain Beach PF02138.18 KFM56661.1 - 6.8e-126 419.3 1.0 1.8e-125 417.9 0.2 2.1 2 0 0 2 2 2 1 Beige/BEACH domain FYVE PF01363.21 KFM56661.1 - 2.2e-17 62.9 10.5 5.7e-17 61.6 10.5 1.8 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.6 KFM56661.1 - 6e-13 48.8 0.0 2.4e-12 46.8 0.0 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFM56661.1 - 4e-11 43.3 7.5 1.7e-05 25.4 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF4800 PF16057.5 KFM56661.1 - 0.0059 15.9 0.2 0.013 14.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) zf_C2HC_14 PF18574.1 KFM56661.1 - 0.45 10.4 3.3 1.3 8.9 3.3 1.7 1 0 0 1 1 1 0 C2HC Zing finger domain IBR PF01485.21 KFM56661.1 - 0.54 10.5 5.1 1.8 8.8 5.1 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF4704 PF15787.5 KFM56662.1 - 5.8e-07 29.0 1.7 1.7e-06 27.5 1.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 KFM56662.1 - 0.00029 21.0 0.1 0.00069 19.8 0.1 1.6 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily HGWP PF03578.15 KFM56662.1 - 0.098 12.2 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 HGWP repeat YqaJ PF09588.10 KFM56667.1 - 0.00019 21.6 0.0 0.00071 19.8 0.0 2.0 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain NDUFB10 PF10249.9 KFM56669.1 - 4e-51 172.8 3.8 4.6e-51 172.6 3.8 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Ig_2 PF13895.6 KFM56670.1 - 1.7e-13 50.7 1.7 4.7e-06 26.9 0.1 3.4 2 2 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFM56670.1 - 2.5e-13 50.4 5.2 1e-06 29.2 0.0 3.8 3 1 1 4 4 4 2 Immunoglobulin domain V-set PF07686.17 KFM56670.1 - 5e-08 33.1 0.5 4.9e-07 29.9 0.0 2.5 2 1 1 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM56670.1 - 1.6e-07 31.2 0.1 1.6e-07 31.2 0.1 2.7 2 1 1 3 3 3 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFM56670.1 - 2e-07 31.1 3.8 7.8e-05 22.8 0.0 4.4 4 1 0 4 4 4 1 Immunoglobulin domain I-set PF07679.16 KFM56670.1 - 1.3e-06 28.3 0.1 0.0037 17.3 0.0 2.9 2 2 0 2 2 2 2 Immunoglobulin I-set domain PDCD9 PF07147.12 KFM56672.1 - 1.2e-09 37.9 0.5 9.7e-09 34.9 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) OsmC PF02566.19 KFM56672.1 - 0.02 15.4 0.0 0.093 13.2 0.0 1.9 2 0 0 2 2 2 0 OsmC-like protein Nop10p PF04135.12 KFM56673.1 - 1.6e-23 82.4 0.2 1.9e-23 82.3 0.2 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Mss4 PF04421.13 KFM56674.1 - 1.7e-27 95.4 0.0 2.6e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Mss4 protein DUF769 PF05590.11 KFM56674.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 1 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) Sedlin_N PF04628.13 KFM56675.1 - 2.1e-30 105.5 0.5 2.6e-30 105.2 0.5 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFM56675.1 - 2.9e-10 40.2 0.4 3.4e-10 40.0 0.4 1.1 1 0 0 1 1 1 1 Sybindin-like family Ank_4 PF13637.6 KFM56676.1 - 5.7e-17 61.8 0.4 6.3e-09 36.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM56676.1 - 2.3e-16 60.1 0.1 2.8e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM56676.1 - 3.5e-14 52.7 0.4 4.6e-05 23.6 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM56676.1 - 1.2e-13 49.9 0.4 0.00011 22.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFM56676.1 - 3.1e-09 36.9 2.1 0.0018 18.6 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KFM56677.1 - 6.9e-32 109.9 3.2 7.3e-17 61.7 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM56677.1 - 5.9e-26 90.5 0.2 1.3e-13 51.1 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM56677.1 - 4.3e-21 74.3 1.9 3e-08 33.7 0.1 5.4 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KFM56677.1 - 1.2e-19 68.3 4.3 1.3e-05 25.1 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KFM56677.1 - 1.2e-18 66.9 0.4 4.8e-07 29.9 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 KFM56678.1 - 4.9e-11 42.9 0.2 1.2e-10 41.7 0.2 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM56678.1 - 2.7e-08 33.8 0.2 4.5e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) BAR_3 PF16746.5 KFM56679.1 - 4.6e-20 72.3 3.5 7.1e-20 71.7 3.5 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PID PF00640.23 KFM56679.1 - 1.2e-13 51.3 0.1 3.4e-13 49.8 0.1 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PH PF00169.29 KFM56679.1 - 6.8e-06 26.5 0.2 3.6e-05 24.2 0.2 2.3 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 KFM56679.1 - 0.0099 15.7 0.2 0.022 14.6 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KFM56679.1 - 0.012 15.9 0.2 0.039 14.3 0.2 1.9 1 0 0 1 1 1 0 Plant pleckstrin homology-like region CxC2 PF18803.1 KFM56679.1 - 0.052 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases PH_6 PF15406.6 KFM56679.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.6 KFM56679.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.3 2 1 1 3 3 3 0 Pleckstrin homology domain BAR_3 PF16746.5 KFM56680.1 - 0.00038 20.2 0.1 0.00039 20.2 0.1 1.0 1 0 0 1 1 1 1 BAR domain of APPL family Peptidase_S46 PF10459.9 KFM56681.1 - 0.11 11.1 0.0 0.28 9.8 0.0 1.5 2 0 0 2 2 2 0 Peptidase S46 AAA_lid_3 PF17862.1 KFM56682.1 - 3.1e-14 52.5 0.0 5.5e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KFM56682.1 - 3.5e-08 34.0 0.0 1.2e-07 32.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFM56682.1 - 0.038 14.0 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA PF00004.29 KFM56683.1 - 4.9e-13 49.7 0.0 8.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KFM56683.1 - 1.6e-06 27.5 0.1 2.8e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_lid_3 PF17862.1 KFM56683.1 - 2.7e-06 27.1 0.1 5.3e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Rad17 PF03215.15 KFM56683.1 - 0.00014 21.9 0.7 0.0004 20.4 0.3 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 KFM56683.1 - 0.00026 21.0 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KFM56683.1 - 0.00027 20.4 0.0 0.0012 18.3 0.0 1.9 1 1 1 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 KFM56683.1 - 0.00076 19.9 0.0 0.023 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KFM56683.1 - 0.00081 19.2 0.1 0.002 17.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFM56683.1 - 0.0053 16.7 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 NTPase Viral_helicase1 PF01443.18 KFM56683.1 - 0.0054 16.5 0.0 0.009 15.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KFM56683.1 - 0.0055 16.4 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.20 KFM56683.1 - 0.0063 15.7 1.2 0.021 14.0 1.1 1.8 1 1 0 1 1 1 1 G-protein alpha subunit AAA_7 PF12775.7 KFM56683.1 - 0.0068 15.9 0.1 0.017 14.7 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 KFM56683.1 - 0.0075 16.8 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 KFM56683.1 - 0.018 14.9 0.2 0.24 11.3 0.1 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KFM56683.1 - 0.023 15.1 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KFM56683.1 - 0.036 14.2 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM56683.1 - 0.041 13.8 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 KFM56683.1 - 0.041 13.2 0.1 0.2 11.0 0.1 1.9 1 1 1 2 2 2 0 KaiC Arf PF00025.21 KFM56683.1 - 0.045 13.2 0.0 0.62 9.5 0.0 2.6 2 1 1 3 3 3 0 ADP-ribosylation factor family AAA_5 PF07728.14 KFM56683.1 - 0.049 13.6 0.0 0.26 11.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM56683.1 - 0.062 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM56683.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 KFM56683.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Myotub-related PF06602.14 KFM56684.1 - 4.9e-31 108.0 0.4 1.1e-29 103.4 0.3 2.0 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain UCH PF00443.29 KFM56685.1 - 3.4e-36 125.1 0.9 4.4e-36 124.7 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM56685.1 - 1.5e-15 57.6 0.5 2.4e-14 53.7 0.5 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BES1_N PF05687.13 KFM56685.1 - 0.012 16.1 0.1 0.024 15.0 0.1 1.4 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal zf-UBP PF02148.19 KFM56685.1 - 0.056 13.8 2.3 0.056 13.8 2.3 3.7 4 1 1 5 5 5 0 Zn-finger in ubiquitin-hydrolases and other protein RRM_1 PF00076.22 KFM56687.1 - 9.2e-63 208.0 0.0 2.9e-22 78.3 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM56687.1 - 4.5e-12 45.7 0.0 0.0002 21.0 0.0 3.7 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM56687.1 - 0.00043 20.1 0.0 0.014 15.2 0.0 2.6 2 1 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFM56687.1 - 0.0086 16.1 0.0 0.82 9.7 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif RNA_bind PF08675.11 KFM56687.1 - 0.013 15.5 0.0 7.8 6.6 0.0 3.7 3 3 0 3 3 3 0 RNA binding domain RRM_7 PF16367.5 KFM56687.1 - 0.033 14.3 0.0 13 6.0 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif RRM_2 PF04059.12 KFM56687.1 - 0.11 12.8 0.1 0.96 9.7 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif 2 RT_RNaseH_2 PF17919.1 KFM56688.1 - 2.4e-40 136.6 0.0 7.2e-40 135.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM56688.1 - 1.4e-36 124.9 0.1 7.5e-36 122.6 0.1 2.3 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM56688.1 - 1.2e-31 110.0 0.0 2.6e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM56688.1 - 1.6e-21 76.7 0.0 2.2e-20 73.0 0.0 2.9 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM56688.1 - 1.3e-19 70.1 0.1 3.5e-19 68.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 KFM56688.1 - 2e-12 47.5 0.0 5.9e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM56688.1 - 2.1e-10 41.1 0.0 7.6e-10 39.3 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease Apolipoprotein PF01442.18 KFM56688.1 - 3.1e-05 23.9 19.9 3.1e-05 23.9 19.9 3.7 5 0 0 5 5 4 1 Apolipoprotein A1/A4/E domain zf-H2C2 PF09337.10 KFM56688.1 - 6.7e-05 23.0 0.0 0.00025 21.2 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 KFM56688.1 - 0.00053 19.8 0.1 0.003 17.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Baculo_PEP_C PF04513.12 KFM56688.1 - 0.0032 17.5 4.1 1.2 9.2 0.5 3.4 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 KFM56688.1 - 0.014 14.7 28.8 0.011 15.0 9.4 3.1 2 1 1 3 3 3 0 SF-assemblin/beta giardin ABC_tran_CTD PF16326.5 KFM56688.1 - 0.019 15.2 0.2 0.019 15.2 0.2 4.2 2 1 1 3 3 1 0 ABC transporter C-terminal domain rve_3 PF13683.6 KFM56688.1 - 0.051 13.4 0.2 0.25 11.1 0.0 2.4 2 0 0 2 2 1 0 Integrase core domain MLVIN_C PF18697.1 KFM56688.1 - 0.072 13.2 0.1 0.21 11.7 0.1 1.8 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain AAA_13 PF13166.6 KFM56688.1 - 0.075 11.7 20.1 0.17 10.5 20.1 1.6 1 0 0 1 1 1 0 AAA domain Prominin PF05478.11 KFM56688.1 - 0.26 9.2 16.3 0.13 10.2 13.7 1.8 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.12 KFM56688.1 - 0.29 11.2 26.1 0.32 11.0 11.6 3.5 2 1 2 4 4 3 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 KFM56688.1 - 0.51 10.4 34.2 0.068 13.3 17.8 3.4 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) ApoO PF09769.9 KFM56688.1 - 0.52 10.3 7.7 12 5.8 2.9 3.1 1 1 1 2 2 2 0 Apolipoprotein O FAM25 PF15825.5 KFM56688.1 - 0.55 10.6 20.6 2.7 8.4 6.5 3.0 1 1 1 2 2 2 0 FAM25 family Mitofilin PF09731.9 KFM56688.1 - 0.59 8.9 27.6 1.3 7.7 27.6 1.5 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF842 PF05811.13 KFM56688.1 - 0.71 9.6 19.1 11 5.7 16.1 3.2 2 1 1 3 3 2 0 Eukaryotic protein of unknown function (DUF842) DDHD PF02862.17 KFM56688.1 - 1.2 9.2 8.5 0.78 9.9 5.7 2.1 2 0 0 2 2 2 0 DDHD domain AIP3 PF03915.13 KFM56688.1 - 1.6 7.8 24.4 4 6.4 22.1 2.5 2 0 0 2 2 2 0 Actin interacting protein 3 Exonuc_VII_L PF02601.15 KFM56688.1 - 2.7 7.5 17.3 0.34 10.4 11.1 2.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Carbpep_Y_N PF05388.11 KFM56688.1 - 3.3 8.3 11.2 25 5.4 10.7 2.9 1 1 0 1 1 1 0 Carboxypeptidase Y pro-peptide DUF4407 PF14362.6 KFM56688.1 - 6.5 6.0 17.8 1.1e+02 2.0 17.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) AAA_32 PF13654.6 KFM56688.1 - 9.3 4.9 21.3 20 3.8 21.3 1.5 1 0 0 1 1 1 0 AAA domain zf-RING_14 PF17978.1 KFM56690.1 - 3.1e-44 149.3 3.3 3.1e-44 149.3 3.3 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_12 PF17976.1 KFM56690.1 - 1.1e-35 121.7 6.1 1.1e-35 121.7 6.1 2.8 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain ubiquitin PF00240.23 KFM56690.1 - 5.8e-14 51.6 0.1 9.4e-14 50.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family IBR PF01485.21 KFM56690.1 - 1.2e-09 38.2 17.1 4.4e-06 26.8 0.6 5.2 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain Rad60-SLD PF11976.8 KFM56690.1 - 4.2e-05 23.3 0.0 8.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KFM56690.1 - 0.002 18.2 0.1 0.0046 17.0 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFM56690.1 - 0.002 18.6 0.0 0.0046 17.5 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain COesterase PF00135.28 KFM56691.1 - 2.2e-28 99.4 0.0 2.5e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Amelogenin PF02948.15 KFM56692.1 - 1.9 9.1 6.6 2.2 8.9 0.7 2.2 2 0 0 2 2 2 0 Amelogenin Ank_2 PF12796.7 KFM56693.1 - 6.5e-78 257.4 11.9 1.3e-18 67.3 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM56693.1 - 2.9e-45 152.1 5.5 4e-10 40.0 0.0 5.8 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFM56693.1 - 6e-42 140.3 9.8 2.2e-05 24.7 0.0 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFM56693.1 - 8.7e-42 140.7 2.5 1.4e-07 31.7 0.0 7.7 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM56693.1 - 9.4e-41 133.1 5.9 0.00014 22.0 0.1 8.4 8 0 0 8 8 8 8 Ankyrin repeat zf-RING_13 PF17977.1 KFM56693.1 - 0.022 14.9 0.5 11 6.3 0.0 3.1 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain ZZ PF00569.17 KFM56694.1 - 0.096 12.5 0.4 0.17 11.7 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, ZZ type FERM_M PF00373.18 KFM56695.1 - 1.6e-16 60.8 0.1 4.7e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 FERM central domain RA PF00788.23 KFM56695.1 - 2.3e-05 25.0 0.0 5.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.10 KFM56695.1 - 8.6e-05 22.4 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_f0 PF16511.5 KFM56695.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM p31comet PF06581.12 KFM56695.1 - 0.13 11.4 0.0 0.43 9.7 0.0 1.7 1 1 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding PDZ PF00595.24 KFM56696.1 - 1.6e-10 41.2 0.0 1.9e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM56696.1 - 2.4e-06 27.8 0.0 3.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM56696.1 - 5.6e-06 26.1 0.0 8.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 PDZ domain MFS_1 PF07690.16 KFM56697.1 - 3.7e-20 72.2 9.3 5.3e-20 71.7 2.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFM56698.1 - 0.015 14.2 17.6 0.028 13.3 17.3 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily Endomucin PF07010.12 KFM56698.1 - 0.15 12.0 0.2 0.23 11.4 0.2 1.2 1 0 0 1 1 1 0 Endomucin MFS_1 PF07690.16 KFM56699.1 - 1.5e-30 106.3 9.2 7.3e-21 74.5 4.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Neur_chan_memb PF02932.16 KFM56700.1 - 3.5e-11 43.6 0.0 3.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 KFM56701.1 - 2.4e-46 158.7 0.0 2.7e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM56701.1 - 8.3e-13 48.3 0.0 1.1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain PMP22_Claudin PF00822.20 KFM56701.1 - 0.014 15.3 0.4 0.021 14.7 0.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF2417 PF10329.9 KFM56701.1 - 0.015 14.7 1.8 0.022 14.2 1.8 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) TMEM138 PF14935.6 KFM56701.1 - 0.017 15.7 2.0 0.029 15.0 2.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 138 NrsF PF06532.11 KFM56701.1 - 0.021 14.5 0.3 0.089 12.5 0.2 1.8 2 0 0 2 2 2 0 Negative regulator of sigma F Tetraspanin PF00335.20 KFM56701.1 - 5 6.8 5.4 11 5.7 4.0 1.8 1 1 1 2 2 2 0 Tetraspanin family Exonuc_VIII PF06630.11 KFM56702.1 - 0.07 13.0 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII ASH PF15780.5 KFM56707.1 - 0.0027 17.9 0.1 0.027 14.7 0.0 2.1 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Ig_mannosidase PF17753.1 KFM56707.1 - 0.025 14.3 0.1 0.57 10.0 0.1 2.2 2 0 0 2 2 2 0 Ig-fold domain DUF4451 PF14616.6 KFM56709.1 - 0.05 13.8 0.2 0.07 13.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) LptF_LptG PF03739.14 KFM56709.1 - 0.2 10.5 0.0 0.23 10.3 0.0 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF1148 PF06618.11 KFM56710.1 - 0.085 13.0 0.0 0.085 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) Choline_transpo PF04515.12 KFM56711.1 - 5.5e-102 341.3 30.9 5.5e-102 341.3 30.9 2.9 3 0 0 3 3 3 1 Plasma-membrane choline transporter DUF3023 PF11224.8 KFM56711.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) Sulfotransfer_1 PF00685.27 KFM56712.1 - 2.8e-76 256.5 1.1 3.4e-76 256.2 1.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM56712.1 - 8.3e-10 39.4 0.0 4.4e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 Sulfotransferase family Biopterin_H PF00351.21 KFM56713.1 - 3.6e-12 46.0 0.0 3.7e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase HTH_32 PF13565.6 KFM56714.1 - 0.0024 18.4 1.8 0.02 15.5 1.8 2.3 1 1 0 1 1 1 1 Homeodomain-like domain E3_UFM1_ligase PF09743.9 KFM56714.1 - 0.0096 15.6 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 TGFb_propeptide PF00688.18 KFM56715.1 - 4e-33 115.2 2.6 4.8e-33 114.9 2.6 1.1 1 0 0 1 1 1 1 TGF-beta propeptide Proteasome PF00227.26 KFM56716.1 - 1e-51 175.2 0.3 1.3e-51 174.8 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM56716.1 - 4.7e-13 48.5 0.3 9.5e-13 47.6 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PIN_2 PF10130.9 KFM56716.1 - 0.028 14.6 0.9 0.054 13.7 0.3 1.7 2 0 0 2 2 2 0 PIN domain ASF1_hist_chap PF04729.13 KFM56716.1 - 0.037 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 ASF1 like histone chaperone RRM_1 PF00076.22 KFM56717.1 - 2.3e-13 49.7 0.4 1.1e-12 47.6 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KFM56717.1 - 0.037 13.8 0.0 0.037 13.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) DUF4434 PF14488.6 KFM56717.1 - 0.068 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Insulin_TMD PF17870.1 KFM56718.1 - 0.0034 17.4 1.7 0.0034 17.4 1.7 2.2 3 0 0 3 3 3 1 Insulin receptor trans-membrane segment eRF1_1 PF03463.15 KFM56718.1 - 0.037 14.0 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 eRF1 domain 1 VHS PF00790.19 KFM56719.1 - 3.9e-46 156.4 0.1 3.9e-46 156.4 0.1 2.7 3 0 0 3 3 3 1 VHS domain Hrs_helical PF12210.8 KFM56719.1 - 1.5e-40 137.7 5.1 1.5e-40 137.7 5.1 2.9 3 1 0 3 3 3 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE PF01363.21 KFM56719.1 - 8e-17 61.2 15.7 8e-17 61.2 15.7 1.9 2 0 0 2 2 2 1 FYVE zinc finger UIM PF02809.20 KFM56719.1 - 0.0028 17.5 4.9 0.0095 15.8 4.9 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif 2OG-FeII_Oxy_3 PF13640.6 KFM56720.1 - 4.2e-09 37.2 0.2 9.7e-09 36.0 0.1 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 KFM56720.1 - 0.00031 20.3 0.0 0.0044 16.6 0.0 2.2 1 1 1 2 2 2 1 Oxygenase, catalysing oxidative methylation of damaged DNA HLH PF00010.26 KFM56721.1 - 2.6e-15 56.1 0.2 5.2e-15 55.1 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TPR_12 PF13424.6 KFM56724.1 - 4e-70 232.1 28.3 9.4e-21 73.9 2.9 5.1 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFM56724.1 - 4.6e-65 213.9 19.6 9.7e-16 57.1 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KFM56724.1 - 1.2e-32 109.5 18.4 4.1e-06 26.4 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFM56724.1 - 1.3e-28 97.6 33.0 3.7e-07 29.7 0.3 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFM56724.1 - 7.9e-22 75.6 28.8 6.4e-05 22.8 1.9 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFM56724.1 - 1.1e-17 62.7 23.1 0.0015 18.6 1.2 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM56724.1 - 8.4e-13 48.4 3.0 8.4e-13 48.4 3.0 3.0 3 1 0 3 3 3 1 MalT-like TPR region TPR_16 PF13432.6 KFM56724.1 - 1.1e-11 45.1 11.2 0.0032 18.1 0.1 5.4 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFM56724.1 - 3e-11 42.9 10.9 0.016 15.5 0.3 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM56724.1 - 4.1e-10 39.6 13.6 0.7 10.9 0.0 6.7 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM56724.1 - 4.3e-09 36.7 17.1 0.00017 22.0 0.4 4.7 4 1 3 7 7 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM56724.1 - 4.8e-07 29.9 9.9 0.0086 16.3 0.4 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KFM56724.1 - 1.5e-06 28.3 0.0 19 6.2 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 KFM56724.1 - 0.00013 22.0 1.2 0.25 11.7 0.0 4.6 6 0 0 6 6 3 1 PPR repeat DUF2225 PF09986.9 KFM56724.1 - 0.0074 16.0 9.5 0.17 11.6 0.4 4.0 3 1 1 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) TMF_TATA_bd PF12325.8 KFM56724.1 - 0.02 15.1 6.8 0.02 15.1 6.8 3.7 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding MIT PF04212.18 KFM56724.1 - 0.03 14.4 13.1 3.7 7.7 1.7 5.9 3 1 2 5 5 5 0 MIT (microtubule interacting and transport) domain NUDE_C PF04880.13 KFM56724.1 - 0.033 14.7 0.6 0.033 14.7 0.6 2.5 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Wzy_C_2 PF11846.8 KFM56724.1 - 0.039 13.9 1.9 7 6.5 0.0 4.0 3 2 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal PPR_2 PF13041.6 KFM56724.1 - 0.11 12.7 2.3 8.8 6.6 0.0 3.6 4 0 0 4 4 2 0 PPR repeat family TPR_11 PF13414.6 KFM56724.1 - 0.15 11.7 25.0 0.084 12.6 0.8 6.6 7 0 0 7 7 7 0 TPR repeat DUF4919 PF16266.5 KFM56724.1 - 0.33 10.9 3.5 0.98 9.3 0.0 3.3 2 1 2 4 4 3 0 Domain of unknown function (DUF4919) TPR_3 PF07720.12 KFM56724.1 - 0.34 10.9 14.7 1.2 9.3 0.4 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.12 KFM56724.1 - 0.38 10.8 7.0 9.7 6.3 0.0 4.6 3 2 2 5 5 5 0 Protein of unknown function (DUF627) SHNi-TPR PF10516.9 KFM56724.1 - 0.52 9.8 6.6 15 5.2 0.1 4.0 4 0 0 4 4 4 0 SHNi-TPR TPR_6 PF13174.6 KFM56724.1 - 0.52 11.1 19.3 3.2 8.6 0.5 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat WbqC PF08889.11 KFM56724.1 - 0.56 10.1 3.3 4.5 7.1 0.0 3.4 2 1 2 4 4 4 0 WbqC-like protein family JIP_LZII PF16471.5 KFM56724.1 - 1.5 9.1 11.2 0.11 12.7 3.1 2.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II GAS PF13851.6 KFM56724.1 - 1.9 7.8 25.4 0.076 12.4 0.7 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 KFM56724.1 - 2.5 8.5 10.8 0.25 11.7 4.0 3.0 2 1 0 2 2 2 0 Csm1 N-terminal domain Jnk-SapK_ap_N PF09744.9 KFM56725.1 - 0.0042 17.3 21.1 0.0042 17.3 21.1 9.6 2 1 8 10 10 10 1 JNK_SAPK-associated protein-1 Mid2 PF04478.12 KFM56725.1 - 0.017 14.9 0.0 0.074 12.9 0.0 2.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 KFM56725.1 - 0.043 13.2 4.0 0.084 12.3 4.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SNAP-25 PF00835.19 KFM56725.1 - 0.6 10.4 3.1 2.9 8.3 3.1 2.2 1 0 0 1 1 1 0 SNAP-25 family RNA_POL_M_15KD PF02150.16 KFM56726.1 - 5.5e-14 51.7 7.8 5.5e-14 51.7 7.8 2.4 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KFM56726.1 - 1e-10 41.3 12.8 1.6e-10 40.6 2.4 3.3 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.6 KFM56726.1 - 0.00051 20.5 6.1 0.033 14.7 0.3 2.2 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain DZR PF12773.7 KFM56726.1 - 0.0071 16.4 2.0 0.0071 16.4 2.0 2.3 2 1 1 3 3 3 1 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KFM56726.1 - 0.0089 15.5 0.2 0.0089 15.5 0.2 3.0 3 1 0 3 3 3 1 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 KFM56726.1 - 0.034 14.4 6.5 1.6 9.1 0.8 2.6 2 0 0 2 2 2 0 zinc-ribbon CpXC PF14353.6 KFM56726.1 - 0.094 12.8 7.9 1.1 9.3 0.4 2.4 1 1 1 2 2 2 0 CpXC protein DUF3716 PF12511.8 KFM56726.1 - 0.11 12.6 9.1 0.34 11.0 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Zn_Tnp_IS1595 PF12760.7 KFM56726.1 - 0.98 9.4 10.1 0.26 11.3 1.2 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.13 KFM56726.1 - 1.1 9.4 9.1 1.4 9.0 0.3 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf_UBZ PF18439.1 KFM56726.1 - 1.4 8.6 8.1 2.3 7.9 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Ogr_Delta PF04606.12 KFM56726.1 - 2.1 8.4 13.4 0.83 9.7 6.2 3.0 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger SR1P PF13790.6 KFM56726.1 - 7.2 6.8 12.7 2.5 8.3 2.2 3.4 3 1 0 3 3 3 0 SR1 protein zinc_ribbon_13 PF09855.9 KFM56726.1 - 8 6.7 9.5 3.4 7.9 1.9 3.0 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Tnp_P_element PF12017.8 KFM56727.1 - 2.2e-18 66.5 0.6 4e-18 65.7 0.6 1.4 1 0 0 1 1 1 1 Transposase protein Ig_3 PF13927.6 KFM56728.1 - 9.3e-13 48.6 0.0 1.5e-06 28.7 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM56728.1 - 7.6e-11 42.2 0.0 8.8e-06 26.0 0.0 3.5 2 2 1 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFM56728.1 - 7e-09 35.8 0.0 9.3e-05 22.5 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM56728.1 - 3.3e-08 33.7 0.1 1.2e-06 28.6 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 KFM56728.1 - 1.5e-06 28.1 0.0 0.01 15.9 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFM56728.1 - 0.00019 21.4 0.0 0.00046 20.2 0.0 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM56728.1 - 0.0028 17.9 0.1 1.1 9.5 0.0 3.3 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain CENP-S PF15630.6 KFM56729.1 - 1.9e-26 92.2 1.3 2.1e-26 92.1 0.3 1.5 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 KFM56729.1 - 9e-08 32.2 1.1 2.3e-07 30.9 1.1 1.7 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 KFM56729.1 - 0.0023 18.0 0.5 0.0036 17.4 0.5 1.3 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit HAUS2 PF15003.6 KFM56729.1 - 0.0047 16.7 0.7 0.0055 16.5 0.7 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Viral_DNA_Zn_bi PF03728.13 KFM56729.1 - 0.018 15.6 1.4 0.037 14.6 0.1 1.9 2 0 0 2 2 2 0 Viral DNA-binding protein, zinc binding domain Selenoprotein_S PF06936.11 KFM56729.1 - 0.038 13.8 0.6 0.049 13.4 0.6 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Histone PF00125.24 KFM56729.1 - 0.042 14.2 2.0 0.056 13.8 0.2 2.1 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Glyco_hydro_18 PF00704.28 KFM56730.1 - 3.2e-90 303.0 0.0 4.5e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 KFM56730.1 - 2.2e-18 66.2 12.8 1.4e-12 47.6 4.6 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain DUF5401 PF17380.2 KFM56730.1 - 0.004 15.3 0.1 0.004 15.3 0.1 3.1 3 0 0 3 3 3 1 Family of unknown function (DUF5401) Dicty_REP PF05086.12 KFM56730.1 - 4.5 5.1 19.8 0.75 7.7 2.3 2.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Ribosomal_S3Ae PF01015.18 KFM56731.1 - 5.8e-79 264.4 6.4 6.7e-79 264.2 6.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KFM56731.1 - 0.034 13.7 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region VESA1_N PF12785.7 KFM56732.1 - 0.21 10.5 0.0 0.25 10.3 0.0 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 NHL PF01436.21 KFM56733.1 - 3.4e-46 153.0 17.1 4.3e-08 32.8 0.2 6.6 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 KFM56733.1 - 3.1e-18 66.0 3.7 3.5e-06 26.4 0.2 4.1 2 2 1 3 3 3 3 6-bladed beta-propeller Filamin PF00630.19 KFM56733.1 - 4.4e-14 53.1 0.0 1.3e-13 51.7 0.0 1.8 1 0 0 1 1 1 1 Filamin/ABP280 repeat SGL PF08450.12 KFM56733.1 - 9.5e-14 51.6 0.8 0.00078 19.1 0.1 5.0 1 1 5 6 6 6 4 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 KFM56733.1 - 1.2e-09 38.1 3.5 1.2e-09 38.1 3.5 3.6 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4_2 PF13923.6 KFM56733.1 - 6.8e-09 35.4 8.5 6.8e-09 35.4 8.5 3.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM56733.1 - 7.8e-08 32.2 8.5 7.8e-08 32.2 8.5 3.1 3 0 0 3 3 1 1 RING-type zinc-finger DUF4934 PF16288.5 KFM56733.1 - 1e-07 31.8 1.7 0.084 12.8 0.1 3.7 1 1 3 4 4 4 2 Domain of unknown function (DUF4934) zf-C3HC4 PF00097.25 KFM56733.1 - 3e-07 30.2 7.1 3e-07 30.2 7.1 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM56733.1 - 3.8e-07 30.0 6.2 3.8e-07 30.0 6.2 4.4 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM56733.1 - 2.7e-06 27.1 6.3 2.7e-06 27.1 6.3 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM56733.1 - 7.1e-06 26.3 7.5 7.1e-06 26.3 7.5 4.0 4 0 0 4 4 3 1 Ring finger domain Prok-RING_4 PF14447.6 KFM56733.1 - 3.5e-05 23.6 7.2 3.5e-05 23.6 7.2 3.3 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFM56733.1 - 7.6e-05 22.8 9.5 7.6e-05 22.8 9.5 4.1 4 1 0 4 4 2 1 zinc finger of C3HC4-type, RING Invasin_D3 PF09134.10 KFM56733.1 - 0.0056 17.0 0.1 0.015 15.6 0.1 1.8 1 0 0 1 1 1 1 Invasin, domain 3 YtkA PF13115.6 KFM56733.1 - 0.0083 16.7 0.1 0.019 15.6 0.1 1.6 1 0 0 1 1 1 1 YtkA-like PQQ_2 PF13360.6 KFM56733.1 - 0.18 11.3 0.0 0.5 9.9 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain zf-ANAPC11 PF12861.7 KFM56733.1 - 1.4 9.1 9.8 0.092 12.8 1.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger VCBS PF13517.6 KFM56733.1 - 2 9.1 3.8 38 5.0 0.5 3.2 2 2 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HSP70 PF00012.20 KFM56735.1 - 6.6e-178 592.6 15.0 2.2e-175 584.3 15.0 2.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM56735.1 - 5.6e-11 41.8 0.0 1.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Raco_middle PF17651.1 KFM56735.1 - 0.12 12.0 0.1 5.7 6.6 0.0 2.8 2 0 0 2 2 2 0 RACo middle region Zip PF02535.22 KFM56735.1 - 2.2 7.4 4.4 3.3 6.8 4.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM165 PF14981.6 KFM56736.1 - 0.13 12.1 0.3 0.25 11.2 0.3 1.6 1 1 0 1 1 1 0 FAM165 family MFS_1 PF07690.16 KFM56737.1 - 4.2e-09 35.8 0.0 7.7e-09 34.9 0.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sin3a_C PF16879.5 KFM56739.1 - 9.9e-71 238.8 4.9 9.9e-71 238.8 4.9 2.5 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein RNase_J_C PF17770.1 KFM56739.1 - 0.32 12.1 8.0 2.4 9.3 0.1 4.2 4 0 0 4 4 4 0 Ribonuclease J C-terminal domain PAH PF02671.21 KFM56740.1 - 1.5e-25 89.0 10.9 3.2e-17 62.4 3.7 2.6 2 1 0 2 2 2 2 Paired amphipathic helix repeat SF3A3 PF16837.5 KFM56740.1 - 0.59 10.7 4.5 2.8 8.5 0.1 2.8 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Globin PF00042.22 KFM56743.1 - 1.7e-10 41.5 0.3 2.3e-10 41.0 0.3 1.2 1 0 0 1 1 1 1 Globin PRCC PF10253.9 KFM56744.1 - 4.5e-09 37.4 0.2 1.4e-08 35.8 0.2 1.9 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Ribosomal_S11 PF00411.19 KFM56745.1 - 1.8e-19 70.2 0.6 2.3e-19 69.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 SNF2_N PF00176.23 KFM56746.1 - 1.3e-65 221.4 0.3 2.4e-64 217.2 0.5 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.24 KFM56746.1 - 3.4e-31 106.9 9.8 2.3e-17 62.6 0.1 4.1 3 1 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KFM56746.1 - 1.1e-20 74.0 0.0 3.2e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM56746.1 - 1.1e-09 38.5 0.0 3.7e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFM56746.1 - 1.8e-08 33.9 0.8 5.8e-08 32.2 0.8 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PIG-F PF06699.11 KFM56747.1 - 5.1e-39 134.3 6.0 6.8e-39 133.9 6.0 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F WTF PF03303.13 KFM56747.1 - 0.16 11.7 6.8 0.1 12.3 5.6 1.3 1 1 0 1 1 1 0 WTF protein SfLAP PF11139.8 KFM56747.1 - 0.89 8.9 6.4 0.2 11.1 3.1 1.6 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein SEA PF01390.20 KFM56749.1 - 5.7e-06 26.4 1.0 5.7e-06 26.4 1.0 3.6 4 0 0 4 4 4 1 SEA domain TIL PF01826.17 KFM56749.1 - 0.029 14.6 3.3 0.047 13.9 3.3 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain EGF_CA PF07645.15 KFM56749.1 - 2.6 8.3 5.6 4.7 7.5 5.6 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain PRP38 PF03371.15 KFM56750.1 - 1.9e-58 197.2 0.0 2.8e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 PRP38 family DUF4407 PF14362.6 KFM56750.1 - 1.2 8.4 7.2 1.7 7.9 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Homeodomain PF00046.29 KFM56751.1 - 1.4e-19 69.6 1.4 2.4e-19 68.9 1.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM56751.1 - 0.00082 19.2 1.2 0.0011 18.8 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain zf-C2H2_3 PF13878.6 KFM56751.1 - 0.095 12.5 2.1 0.2 11.5 2.1 1.6 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO LIM PF00412.22 KFM56752.1 - 6.4e-16 58.3 6.4 7.9e-16 58.0 6.4 1.1 1 0 0 1 1 1 1 LIM domain NinD PF17466.2 KFM56752.1 - 0.0053 16.8 2.2 0.0071 16.4 2.2 1.3 1 1 0 1 1 1 1 Family of unknown function Fer4_2 PF12797.7 KFM56752.1 - 0.1 12.7 3.0 1.6 9.0 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain DZR PF12773.7 KFM56752.1 - 0.23 11.5 5.7 1.1 9.4 5.9 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KFM56752.1 - 1.3 8.6 0.0 1.3 8.6 0.0 2.9 3 1 0 3 3 3 0 zinc-ribbon domain HTH_Tnp_Tc3_2 PF01498.18 KFM56753.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM56753.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM56753.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM56753.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM56753.1 - 2.1 9.1 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Ndr PF03096.14 KFM56754.1 - 2.5e-104 347.9 0.0 3.1e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 KFM56754.1 - 0.044 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM56754.1 - 0.078 12.2 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GATase_2 PF00310.21 KFM56758.1 - 2.3e-176 586.7 0.0 3.1e-176 586.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KFM56758.1 - 1.3e-152 508.2 1.2 2.7e-152 507.2 0.2 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KFM56758.1 - 1.2e-112 375.9 0.1 2e-111 372.0 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KFM56758.1 - 5.3e-81 270.8 0.1 9.2e-81 270.0 0.1 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KFM56758.1 - 1.2e-25 90.4 0.0 1.4e-24 86.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KFM56758.1 - 1.5e-21 76.2 0.2 4.4e-21 74.8 0.2 1.9 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KFM56758.1 - 7.8e-10 38.8 0.0 1.2e-08 35.1 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFM56758.1 - 5.1e-09 36.6 0.2 1.2e-05 25.8 0.1 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM56758.1 - 4.9e-07 29.3 0.1 0.0022 17.3 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFM56758.1 - 5.9e-07 29.1 0.2 2.7e-06 27.0 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KFM56758.1 - 4.5e-06 26.3 0.8 9.1e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFM56758.1 - 6.3e-06 25.1 0.7 7.8e-05 21.6 0.1 2.5 2 0 0 2 2 2 1 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 KFM56758.1 - 2.6e-05 24.2 0.0 8.7e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 KFM56758.1 - 8.4e-05 22.0 0.0 0.25 10.6 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFM56758.1 - 9.6e-05 21.6 1.2 0.00093 18.4 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KFM56758.1 - 0.00026 20.7 2.2 0.0027 17.3 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KFM56758.1 - 0.0003 20.0 0.1 0.12 11.4 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KFM56758.1 - 0.0009 18.5 1.4 0.0077 15.5 0.1 2.7 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 KFM56758.1 - 0.0039 17.6 0.1 3.8 8.0 0.0 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KFM56758.1 - 0.0047 16.2 0.2 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DJ-1_PfpI PF01965.24 KFM56758.1 - 0.0054 16.5 0.1 2.1 8.2 0.0 3.3 3 0 0 3 3 3 1 DJ-1/PfpI family FMO-like PF00743.19 KFM56758.1 - 0.0091 14.5 0.1 0.39 9.1 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like ApbA PF02558.16 KFM56758.1 - 0.011 15.3 0.1 0.025 14.2 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA YGGT PF02325.17 KFM56758.1 - 0.021 15.3 0.1 7.5 7.1 0.0 2.6 2 0 0 2 2 2 0 YGGT family NAD_binding_2 PF03446.15 KFM56758.1 - 0.022 14.9 0.0 0.081 13.1 0.0 2.0 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_9 PF13454.6 KFM56758.1 - 0.028 14.4 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FMN_dh PF01070.18 KFM56758.1 - 0.049 12.6 0.8 0.16 10.9 0.3 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase GATase_6 PF13522.6 KFM56758.1 - 0.064 13.4 0.1 0.28 11.4 0.1 2.1 3 0 0 3 3 1 0 Glutamine amidotransferase domain YjeF_N PF03853.15 KFM56758.1 - 0.078 12.9 0.0 4.7 7.1 0.0 2.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus IlvN PF07991.12 KFM56758.1 - 0.1 12.2 0.1 0.28 10.7 0.1 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 KFM56758.1 - 0.12 11.3 0.1 5.2 6.0 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KFM56758.1 - 0.17 11.2 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ANTH PF07651.16 KFM56759.1 - 5.6e-69 232.2 0.5 7.8e-69 231.7 0.5 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFM56759.1 - 5.3e-14 52.3 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 ENTH domain S8_pro-domain PF16470.5 KFM56760.1 - 0.0013 19.5 0.0 0.0028 18.4 0.0 1.5 2 0 0 2 2 2 1 Peptidase S8 pro-domain Pkinase PF00069.25 KFM56761.1 - 3.8e-68 229.7 0.0 4.7e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM56761.1 - 8.2e-33 113.8 0.0 5.9e-32 111.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM56761.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM56761.1 - 0.0098 14.9 0.0 0.079 11.9 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM56761.1 - 0.036 14.0 0.2 0.07 13.0 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM56761.1 - 0.19 11.1 0.0 0.59 9.4 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UCH PF00443.29 KFM56762.1 - 6.2e-50 170.1 2.5 6.2e-50 170.1 2.5 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM56762.1 - 2e-16 60.5 2.4 2e-16 60.5 2.4 3.6 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase AAA_5 PF07728.14 KFM56763.1 - 0.037 14.0 0.0 0.069 13.1 0.0 1.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KFM56764.1 - 7.7e-71 237.3 0.0 1e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_1 PF17857.1 KFM56764.1 - 3.1e-08 33.8 0.5 6.6e-08 32.7 0.1 1.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KFM56764.1 - 0.0012 18.8 0.0 0.0025 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KFM56764.1 - 0.023 14.4 0.1 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KFM56764.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KFM56764.1 - 0.061 13.7 0.2 0.099 13.1 0.0 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_8 PF12780.7 KFM56765.1 - 9.9e-33 113.6 0.0 1.1e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 KFM56766.1 - 4.9e-24 85.0 0.6 5.5e-24 84.8 0.6 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor OAF PF14941.6 KFM56766.1 - 0.1 12.0 0.6 0.12 11.8 0.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Spc7 PF08317.11 KFM56766.1 - 0.12 11.2 7.6 0.15 10.9 7.2 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein PCRF PF03462.18 KFM56766.1 - 0.29 11.0 5.3 0.36 10.7 5.3 1.1 1 0 0 1 1 1 0 PCRF domain AAA_9 PF12781.7 KFM56767.1 - 2.1e-05 23.7 0.0 5.5e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_9 PF12781.7 KFM56768.1 - 1.4e-31 109.3 0.0 1.5e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 KFM56769.1 - 1.5e-09 37.9 0.0 1.8e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KFM56770.1 - 2.6e-12 46.8 0.1 2.9e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 KFM56772.1 - 3e-105 351.8 0.0 3.4e-105 351.7 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Pur_DNA_glyco PF02245.16 KFM56773.1 - 9.2e-60 201.1 0.0 1.2e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) LRR_9 PF14580.6 KFM56774.1 - 6e-87 289.6 2.5 7.9e-87 289.2 2.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFM56774.1 - 4.6e-09 36.4 14.3 6.4e-05 23.2 3.0 3.6 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM56774.1 - 4e-05 23.3 13.0 0.00053 19.7 9.4 3.0 1 1 2 3 3 3 3 Leucine rich repeat DM4_12 PF07841.13 KFM56775.1 - 0.16 12.7 0.1 0.16 12.7 0.1 1.9 2 0 0 2 2 2 0 DM4/DM12 family DUF908 PF06012.12 KFM56775.1 - 4.8 6.5 10.4 7.8 5.8 10.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MIF4G PF02854.19 KFM56777.1 - 1.4e-12 47.7 0.1 5.3e-06 26.2 0.1 2.1 2 0 0 2 2 2 2 MIF4G domain MTCP1 PF08991.10 KFM56777.1 - 0.06 13.6 0.4 0.06 13.6 0.4 2.3 1 1 1 2 2 2 0 Mature-T-Cell Proliferation I type eIF-3_zeta PF05091.12 KFM56779.1 - 1.9e-222 739.9 7.6 2.2e-222 739.7 7.6 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 KFM56779.1 - 3.1e-06 26.8 0.0 5.2e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Forkhead PF00250.18 KFM56780.1 - 3.7e-40 136.1 0.2 6.7e-40 135.2 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KFM56780.1 - 2.1e-09 37.6 0.0 3.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 KFM56780.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 linker histone H1 and H5 family Septin PF00735.18 KFM56781.1 - 1.1e-27 97.0 0.1 1.3e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 Septin Septin PF00735.18 KFM56782.1 - 2e-74 250.4 0.1 2.3e-74 250.2 0.1 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFM56782.1 - 2.1e-08 34.2 0.0 3.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM56782.1 - 1.5e-07 31.4 1.8 6.2e-06 26.2 0.4 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KFM56782.1 - 4.8e-06 27.1 0.1 7.2e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KFM56782.1 - 0.00019 21.9 0.1 0.00034 21.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 KFM56782.1 - 0.0015 18.6 1.1 0.18 11.8 0.3 2.4 1 1 1 2 2 2 1 Dynamin family NB-ARC PF00931.22 KFM56782.1 - 0.0018 17.5 0.1 0.0033 16.7 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 KFM56782.1 - 0.0033 16.8 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family GTP_EFTU PF00009.27 KFM56782.1 - 0.0036 16.9 0.5 0.099 12.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain T2SSE PF00437.20 KFM56782.1 - 0.0046 16.1 0.4 0.0086 15.2 0.1 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AIG1 PF04548.16 KFM56782.1 - 0.0049 16.2 0.5 0.0093 15.3 0.4 1.5 1 1 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 KFM56782.1 - 0.0069 16.7 0.2 0.012 15.8 0.3 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFM56782.1 - 0.022 14.7 1.2 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 KFM56782.1 - 0.026 14.8 0.4 0.82 9.9 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFM56782.1 - 0.028 14.2 0.2 0.51 10.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KFM56782.1 - 0.028 13.9 0.1 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.6 KFM56782.1 - 0.029 14.1 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KFM56782.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFM56782.1 - 0.037 13.8 0.0 4.2 7.1 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation 2-oxogl_dehyd_N PF16078.5 KFM56782.1 - 0.038 13.6 0.2 0.061 12.9 0.2 1.3 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Roc PF08477.13 KFM56782.1 - 0.043 14.0 0.1 0.086 13.1 0.1 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KFM56782.1 - 0.068 13.3 0.5 0.26 11.4 0.5 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM56782.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Ras PF00071.22 KFM56782.1 - 0.11 12.0 0.3 0.48 10.0 0.2 2.1 2 1 0 2 2 2 0 Ras family Sigma54_activat PF00158.26 KFM56782.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain G-alpha PF00503.20 KFM56782.1 - 0.17 11.0 1.8 1.3 8.1 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit DDE_3 PF13358.6 KFM56783.1 - 1.2e-11 44.6 0.0 2.5e-11 43.6 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease PhetRS_B1 PF18262.1 KFM56783.1 - 0.15 12.3 0.0 6 7.2 0.0 2.2 1 1 1 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain 7tm_2 PF00002.24 KFM56785.1 - 3.3e-13 49.5 30.7 5.5e-13 48.8 30.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFM56785.1 - 5.4e-10 39.6 0.3 1.3e-09 38.4 0.3 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif YdjM PF04307.14 KFM56785.1 - 7.4 5.8 11.6 0.1 11.9 2.2 2.4 2 1 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase Kazal_2 PF07648.15 KFM56786.1 - 3.5e-08 33.4 4.9 3.5e-08 33.4 4.9 2.2 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM56786.1 - 2.5e-05 24.2 5.2 3.4e-05 23.8 3.0 2.3 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Integrase_H2C2 PF17921.1 KFM56787.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Integrase zinc binding domain Hce2 PF14856.6 KFM56787.1 - 0.033 14.5 0.0 0.079 13.3 0.0 1.7 1 1 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor Glu_synthase PF01645.17 KFM56787.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase HTH_Tnp_Tc3_2 PF01498.18 KFM56789.1 - 1.8e-15 56.9 2.7 1.9e-15 56.9 1.1 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM56789.1 - 7.4e-12 45.3 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM56789.1 - 0.0021 18.7 5.1 0.0031 18.1 1.2 2.7 3 0 0 3 3 3 1 Homeodomain-like domain LRR_6 PF13516.6 KFM56790.1 - 5.7e-30 100.8 6.2 0.0012 18.7 0.0 11.4 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 KFM56790.1 - 3.2e-12 46.4 0.2 0.067 13.6 0.0 7.0 3 3 4 8 8 8 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KFM56790.1 - 1.5e-10 40.8 5.9 4.4e-10 39.3 5.9 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KFM56790.1 - 2.8e-08 33.2 9.9 1.1e+02 4.0 0.1 10.5 9 2 0 9 9 9 0 Leucine Rich Repeat F-box PF00646.33 KFM56790.1 - 6.5e-08 32.3 5.2 6.5e-08 32.3 5.2 2.8 3 0 0 3 3 3 1 F-box domain Mito_carr PF00153.27 KFM56791.1 - 2.3e-36 123.6 0.5 1.6e-16 60.0 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein Mito_carr PF00153.27 KFM56792.1 - 2.9e-09 36.7 0.2 3.3e-09 36.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Phospholip_A2_1 PF00068.19 KFM56793.1 - 4.9e-31 107.5 10.6 5.8e-31 107.3 10.6 1.1 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFM56793.1 - 0.0046 17.1 0.0 0.0081 16.3 0.0 1.4 1 0 0 1 1 1 1 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.12 KFM56793.1 - 0.019 15.2 17.3 0.35 11.1 17.3 2.3 1 1 0 1 1 1 0 Phospholipase A2 EB PF01683.18 KFM56793.1 - 0.24 11.7 14.4 1 9.7 4.7 2.3 2 0 0 2 2 2 0 EB module 7tm_3 PF00003.22 KFM56794.1 - 7.8e-21 74.9 5.8 8.5e-21 74.8 5.8 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR 7tm_3 PF00003.22 KFM56795.1 - 1.2e-25 90.7 10.3 1.3e-25 90.5 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF3789 PF12664.7 KFM56795.1 - 0.23 11.2 2.4 0.29 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) 7tm_1 PF00001.21 KFM56798.1 - 4e-10 39.4 0.7 4e-10 39.4 0.7 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM56798.1 - 3.5e-05 23.3 0.3 5.9e-05 22.6 0.1 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx CD24 PF14984.6 KFM56798.1 - 0.018 15.2 1.2 0.28 11.4 0.4 2.2 2 0 0 2 2 2 0 CD24 protein Cid2 PF09774.9 KFM56799.1 - 1.3e-19 71.1 4.9 5.2e-18 66.0 4.9 2.0 1 1 0 1 1 1 1 Caffeine-induced death protein 2 OSTMP1 PF09777.9 KFM56799.1 - 0.00018 21.0 0.7 0.00022 20.7 0.6 1.3 1 1 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor MAP65_ASE1 PF03999.12 KFM56799.1 - 0.0024 16.6 2.6 0.0032 16.2 2.6 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF505 PF04458.12 KFM56799.1 - 0.012 14.1 0.5 0.012 14.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Arm PF00514.23 KFM56800.1 - 1.3e-91 298.2 15.7 1.3e-12 47.3 0.7 8.5 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFM56800.1 - 4.7e-29 100.4 2.1 1.1e-06 29.0 0.1 6.8 6 1 1 7 7 6 6 HEAT-like repeat IBB PF01749.20 KFM56800.1 - 3.3e-23 81.9 1.9 7e-23 80.9 1.9 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 KFM56800.1 - 1.3e-20 73.5 0.1 1.2e-05 25.6 0.0 5.2 1 1 3 5 5 5 5 HEAT repeats HEAT PF02985.22 KFM56800.1 - 1.5e-19 68.4 9.2 0.015 15.5 0.0 8.3 8 0 0 8 8 8 4 HEAT repeat HEAT_PBS PF03130.16 KFM56800.1 - 1.4e-06 28.4 0.1 28 5.8 0.0 6.1 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 KFM56800.1 - 1.2e-05 25.4 1.4 4.6 7.5 0.0 5.6 4 1 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 KFM56800.1 - 0.00014 22.0 0.1 0.011 15.8 0.0 3.1 3 0 0 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.13 KFM56800.1 - 0.00072 19.1 0.1 0.055 12.9 0.1 2.6 2 1 0 2 2 2 1 Armadillo-like Adaptin_N PF01602.20 KFM56800.1 - 0.00075 18.2 1.4 0.19 10.2 0.3 2.8 1 1 3 4 4 4 3 Adaptin N terminal region Atx10homo_assoc PF09759.9 KFM56800.1 - 0.00082 19.4 0.5 0.8 9.8 0.0 3.0 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 KFM56800.1 - 0.0046 17.0 0.1 1.7 8.7 0.1 2.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 NopRA1 PF16201.5 KFM56800.1 - 0.0079 15.8 0.1 3.2 7.3 0.0 3.7 2 2 1 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 NUSAP PF16006.5 KFM56800.1 - 2.2 8.0 5.8 2.9 7.6 5.8 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein HTH_48 PF17906.1 KFM56801.1 - 1.2e-07 31.7 0.3 2.4e-07 30.7 0.3 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM56801.1 - 4.3e-06 27.3 0.5 3.4e-05 24.3 0.1 2.3 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM56801.1 - 8.4e-05 22.6 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM56801.1 - 0.00016 21.6 0.2 0.0023 17.9 0.0 2.2 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KFM56801.1 - 0.00067 19.4 0.3 0.01 15.6 0.0 2.6 2 1 1 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 KFM56801.1 - 0.11 12.0 0.0 0.34 10.5 0.0 1.7 1 1 1 2 2 2 0 Winged helix-turn-helix DNA-binding DUF937 PF06078.11 KFM56801.1 - 0.13 12.9 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) ACTH_domain PF00976.18 KFM56802.1 - 0.15 12.0 0.6 0.24 11.4 0.6 1.3 1 0 0 1 1 1 0 Corticotropin ACTH domain E3_UbLigase_R4 PF13764.6 KFM56803.1 - 0 1129.8 1.6 0 1129.8 1.6 3.1 4 0 0 4 4 4 1 E3 ubiquitin-protein ligase UBR4 zf-UBR PF02207.20 KFM56803.1 - 1.1e-06 28.7 15.3 1.1e-06 28.7 15.3 3.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) UPF0547 PF10571.9 KFM56803.1 - 4.6 7.4 14.3 0.14 12.3 6.6 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 CTU2 PF10288.9 KFM56803.1 - 5.4 7.3 13.9 2.9 8.1 0.5 4.2 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 Trypan_PARP PF05887.11 KFM56805.1 - 1.9 8.5 15.6 0.032 14.2 6.2 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PHD_2 PF13831.6 KFM56806.1 - 2.4e-15 55.8 3.4 2.4e-15 55.8 3.4 2.5 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 KFM56806.1 - 9e-11 41.5 8.5 9e-11 41.5 8.5 1.9 1 1 1 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KFM56806.1 - 0.059 13.5 10.6 0.51 10.5 4.0 2.2 2 1 0 2 2 2 0 PHD-zinc-finger like domain zf-PHD-like PF15446.6 KFM56806.1 - 0.066 12.8 9.6 0.24 11.0 9.6 1.8 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KFM56806.1 - 0.42 10.5 14.4 0.16 11.9 3.6 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 KFM56806.1 - 0.74 10.1 11.7 4.1 7.7 7.4 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-UDP PF14569.6 KFM56806.1 - 1.6 8.9 9.8 2.6 8.2 9.8 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger ARGLU PF15346.6 KFM56807.1 - 3.6e-52 176.3 60.8 3.6e-52 176.3 60.8 1.6 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 Lys-AminoMut_A PF09043.11 KFM56807.1 - 6.8 5.0 9.3 9.4 4.6 9.3 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Exonuc_VII_L PF02601.15 KFM56807.1 - 9.7 5.7 21.2 15 5.1 21.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ion_trans PF00520.31 KFM56808.1 - 0.016 14.5 4.5 0.017 14.3 4.5 1.1 1 0 0 1 1 1 0 Ion transport protein Ion_trans PF00520.31 KFM56809.1 - 1.3e-16 60.6 3.1 1.5e-16 60.3 3.1 1.1 1 0 0 1 1 1 1 Ion transport protein DUF5445 PF17520.2 KFM56809.1 - 3.5 7.6 5.8 1.4 8.8 0.7 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5445) Ion_trans PF00520.31 KFM56810.1 - 0.00087 18.6 0.1 0.00087 18.6 0.1 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KFM56811.1 - 5.8e-17 61.7 5.2 5.8e-17 61.7 5.2 2.2 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KFM56811.1 - 0.042 12.5 4.9 0.073 11.7 4.9 1.4 1 0 0 1 1 1 0 Polycystin cation channel Ion_trans PF00520.31 KFM56812.1 - 2.2e-38 131.9 10.4 3.1e-33 115.0 5.9 2.0 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KFM56812.1 - 3.6e-05 22.6 5.1 0.00012 20.9 0.4 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 KFM56813.1 - 7.6e-16 58.1 11.0 7.6e-16 58.1 11.0 1.6 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KFM56813.1 - 0.0007 18.4 5.0 0.0012 17.6 4.2 1.8 1 1 0 1 1 1 1 Polycystin cation channel ARID PF01388.21 KFM56815.1 - 0.04 14.6 0.0 0.041 14.6 0.0 1.1 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain Cadherin-like PF12733.7 KFM56817.1 - 1.5e-05 25.4 0.5 1.8e-05 25.2 0.5 1.1 1 0 0 1 1 1 1 Cadherin-like beta sandwich domain PC-Esterase PF13839.6 KFM56818.1 - 0.091 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p HobA PF12163.8 KFM56818.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA replication regulator DUF5605 PF18310.1 KFM56819.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) Babuvirus_MP PF07234.11 KFM56820.1 - 0.87 9.8 3.8 0.87 9.8 3.8 1.1 1 0 0 1 1 1 0 Movement and RNA silencing protein Sushi PF00084.20 KFM56822.1 - 7.1e-10 39.3 0.3 7.1e-10 39.3 0.3 3.5 4 0 0 4 4 4 2 Sushi repeat (SCR repeat) RRM_1 PF00076.22 KFM56824.1 - 3.9e-06 26.6 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM56824.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RR_TM4-6 PF06459.12 KFM56824.1 - 0.79 9.5 19.6 1.9 8.2 19.6 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF676 PF05057.14 KFM56827.1 - 7.5e-45 153.1 0.0 9.3e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KFM56827.1 - 2.4e-06 27.6 0.0 4.3e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFM56827.1 - 9.3e-06 25.5 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KFM56827.1 - 0.0017 17.6 0.1 0.0025 17.1 0.1 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase 4HBT_2 PF13279.6 KFM56829.1 - 0.026 15.0 0.6 0.027 15.0 0.6 1.0 1 0 0 1 1 1 0 Thioesterase-like superfamily RTT107_BRCT_5 PF16770.5 KFM56831.1 - 0.11 12.4 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain RVT_2 PF07727.14 KFM56833.1 - 1.6e-68 230.9 4.6 1.6e-68 230.9 4.6 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KFM56833.1 - 1.5e-26 92.7 0.9 5.5e-26 90.9 0.9 2.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 KFM56833.1 - 2.7e-19 69.5 0.0 1.3e-17 64.1 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain DDE_3 PF13358.6 KFM56833.1 - 9.2e-11 41.7 0.0 2.3e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 DDE superfamily endonuclease gag_pre-integrs PF13976.6 KFM56833.1 - 1.8e-06 27.7 0.2 5.6e-06 26.1 0.2 2.0 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 KFM56833.1 - 3e-05 23.9 8.9 5.6e-05 23.0 5.0 2.6 2 0 0 2 2 2 1 Zinc knuckle PAP_central PF04928.17 KFM56834.1 - 1.5e-110 368.0 0.0 2.1e-110 367.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFM56834.1 - 7e-27 94.1 1.5 2.5e-18 66.3 0.0 2.5 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KFM56834.1 - 1.3e-10 41.4 0.1 3.5e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain 2-oxoacid_dh PF00198.23 KFM56835.1 - 4.2e-80 268.5 0.6 5.4e-80 268.2 0.6 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFM56835.1 - 4.5e-21 74.5 0.9 8.1e-21 73.6 0.9 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFM56835.1 - 0.0001 22.1 0.3 0.00041 20.1 0.2 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 KFM56835.1 - 0.00064 19.6 0.2 0.0019 18.1 0.2 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 KFM56835.1 - 0.0024 17.1 0.0 0.0051 16.1 0.0 1.5 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KFM56835.1 - 0.042 13.8 0.2 0.083 12.8 0.2 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein CHZ PF09649.10 KFM56835.1 - 4.4 6.8 5.9 0.38 10.2 0.9 1.8 2 0 0 2 2 2 0 Histone chaperone domain CHZ ABC1 PF03109.16 KFM56836.1 - 9.7e-34 116.1 0.0 2.8e-33 114.6 0.0 1.9 1 0 0 1 1 1 1 ABC1 family SoxE PF06525.11 KFM56836.1 - 0.076 12.5 1.1 0.14 11.6 1.1 1.4 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain zf-RING_2 PF13639.6 KFM56837.1 - 2e-11 44.1 7.0 3.3e-11 43.3 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFM56837.1 - 4e-08 33.4 9.3 1.8e-07 31.3 9.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM56837.1 - 1.2e-06 28.3 6.1 2.3e-06 27.4 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM56837.1 - 1.7e-06 27.8 5.9 2.9e-06 27.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM56837.1 - 1.2e-05 25.2 3.6 2.8e-05 24.1 3.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KFM56837.1 - 1.6e-05 24.6 3.2 1.6e-05 24.6 3.2 2.2 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KFM56837.1 - 2.2e-05 24.0 4.0 4e-05 23.2 4.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KFM56837.1 - 4e-05 23.5 5.8 7.2e-05 22.7 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM56837.1 - 4.2e-05 23.3 5.5 8.8e-05 22.3 5.6 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFM56837.1 - 0.0014 18.7 5.6 0.0079 16.2 5.6 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFM56837.1 - 0.002 17.9 4.9 0.0038 17.1 4.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KFM56837.1 - 0.0049 17.0 2.1 0.011 15.9 2.1 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 KFM56837.1 - 0.062 13.5 0.9 0.14 12.3 0.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family zf-RING-like PF08746.11 KFM56837.1 - 0.083 13.2 6.2 0.14 12.5 6.2 1.4 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.6 KFM56837.1 - 0.085 13.1 1.1 0.19 12.0 1.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain RINGv PF12906.7 KFM56837.1 - 0.16 12.1 6.4 0.37 11.0 6.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 KFM56837.1 - 0.34 10.8 1.7 0.97 9.3 1.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KFM56837.1 - 0.36 11.0 2.2 1.1 9.5 2.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KFM56837.1 - 0.58 10.2 6.8 0.099 12.7 1.8 2.2 2 0 0 2 2 2 0 Zinc-finger zf-RING_4 PF14570.6 KFM56837.1 - 1.4 8.8 3.4 2.8 7.8 3.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zf_RING PF16744.5 KFM56837.1 - 2.3 8.4 5.0 1.9 8.7 2.6 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger MRP-S22 PF10245.9 KFM56838.1 - 0.024 14.4 0.1 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 CLASP_N PF12348.8 KFM56839.1 - 7.3e-06 25.7 0.2 1.2e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 CLASP N terminal Response_reg PF00072.24 KFM56839.1 - 0.0095 16.1 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain GAGA_bind PF06217.12 KFM56839.1 - 1.7 8.9 5.7 2 8.7 5.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Profilin PF00235.19 KFM56841.1 - 2.4e-37 128.0 0.0 2.7e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Profilin Pex2_Pex12 PF04757.14 KFM56842.1 - 3.7e-24 85.6 4.6 4.6e-24 85.2 4.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KFM56842.1 - 5.4e-11 42.2 7.1 9.1e-11 41.4 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM56842.1 - 7.7e-10 38.9 11.5 1.8e-09 37.8 11.5 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFM56842.1 - 2.4e-09 36.9 7.8 3.7e-09 36.3 7.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFM56842.1 - 6.3e-09 35.6 11.1 1.3e-08 34.5 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM56842.1 - 1e-08 34.8 10.8 2.2e-08 33.8 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM56842.1 - 1.3e-06 28.2 8.4 2.3e-06 27.5 8.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFM56842.1 - 3.1e-06 27.4 8.8 9.3e-06 25.8 8.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM56842.1 - 8.6e-06 25.7 13.5 9e-06 25.6 4.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM56842.1 - 0.00054 20.1 9.3 0.0016 18.5 9.3 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFM56842.1 - 0.003 17.3 6.2 0.006 16.4 6.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KFM56842.1 - 0.081 13.0 7.0 0.045 13.8 4.2 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFM56842.1 - 0.18 11.4 6.6 0.35 10.5 6.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 KFM56842.1 - 0.55 10.4 8.3 1.2 9.3 8.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KFM56842.1 - 5.7 6.8 11.1 4.8 7.0 5.6 2.6 2 0 0 2 2 2 0 RING-like zinc finger R3H PF01424.22 KFM56843.1 - 7.7e-20 70.6 0.1 1.5e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KFM56843.1 - 1.5e-10 40.9 97.9 1.1e-05 25.3 14.2 13.7 13 2 0 13 13 13 7 NF-X1 type zinc finger Guanylate_cyc PF00211.20 KFM56845.1 - 7.7e-70 234.2 0.1 1.2e-69 233.6 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFM56845.1 - 7.8e-37 126.8 3.8 1.2e-36 126.3 3.8 1.3 1 0 0 1 1 1 1 Heme NO binding associated Peptidase_M16 PF00675.20 KFM56847.1 - 0.0013 18.8 0.0 0.0013 18.7 0.0 1.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFM56848.1 - 7.1e-11 42.5 0.0 8e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 KFM56849.1 - 4.2e-76 255.4 0.8 5.9e-76 254.9 0.8 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M1 PF01433.20 KFM56850.1 - 3.2e-23 82.4 1.3 3.2e-23 82.4 1.3 2.0 2 1 0 2 2 2 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFM56850.1 - 7.3e-14 51.8 0.7 7.3e-14 51.8 0.7 2.2 3 1 0 3 3 3 1 Leukotriene A4 hydrolase, C-terminal Amino_oxidase PF01593.24 KFM56850.1 - 0.03 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Rab5ip PF07019.12 KFM56851.1 - 1.5e-20 73.5 11.7 1.9e-20 73.2 11.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vpu PF00558.19 KFM56851.1 - 7.6 6.4 7.1 1.2 8.9 0.5 2.3 2 1 1 3 3 3 0 Vpu protein ERAP1_C PF11838.8 KFM56852.1 - 2.3e-88 296.8 2.1 3.4e-88 296.2 2.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF1952 PF09189.10 KFM56852.1 - 0.029 14.2 0.4 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1952) Pkinase PF00069.25 KFM56853.1 - 1.8e-69 234.0 0.0 2.2e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM56853.1 - 7.2e-34 117.2 0.0 9.9e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM56853.1 - 1.2e-05 24.8 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM56853.1 - 7.3e-05 21.9 0.0 0.00022 20.3 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM56853.1 - 0.00038 19.9 0.1 0.00065 19.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM56853.1 - 0.0096 15.9 0.0 0.025 14.5 0.0 1.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFM56853.1 - 0.048 12.7 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Chitin_synth_2 PF03142.15 KFM56856.1 - 1.1e-30 106.8 2.2 3.3e-25 88.7 1.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFM56856.1 - 7.6e-14 52.1 3.4 1.4e-12 48.0 2.8 3.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFM56856.1 - 1.3e-06 28.4 0.1 3.2e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFM56856.1 - 0.035 13.6 0.1 0.36 10.3 0.1 2.4 1 1 0 1 1 1 0 Glycosyl transferase family 21 HR1 PF02185.16 KFM56856.1 - 0.85 9.8 5.5 35 4.6 0.1 3.7 3 0 0 3 3 3 0 Hr1 repeat SLX9 PF15341.6 KFM56857.1 - 2.2e-05 24.9 2.9 2.2e-05 24.9 2.9 2.3 1 1 2 3 3 3 1 Ribosome biogenesis protein SLX9 Retrotrans_gag PF03732.17 KFM56857.1 - 0.00013 22.2 0.7 0.00023 21.4 0.2 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein GED PF02212.18 KFM56857.1 - 0.056 13.6 1.4 0.14 12.3 1.4 1.7 1 0 0 1 1 1 0 Dynamin GTPase effector domain EGF PF00008.27 KFM56858.1 - 3.6e-55 183.8 103.1 2.5e-08 34.0 4.2 8.7 9 0 0 9 9 9 8 EGF-like domain EGF_2 PF07974.13 KFM56858.1 - 0.0011 19.2 125.9 0.0044 17.4 5.5 9.4 10 0 0 10 10 10 7 EGF-like domain FOLN PF09289.10 KFM56858.1 - 0.0041 17.3 26.5 11 6.3 2.0 9.3 9 0 0 9 9 9 1 Follistatin/Osteonectin-like EGF domain DUF2080 PF09853.9 KFM56858.1 - 0.0079 15.9 9.5 45 3.9 0.0 6.4 7 0 0 7 7 7 0 Putative transposon-encoded protein (DUF2080) EGF_3 PF12947.7 KFM56858.1 - 0.32 11.2 102.4 0.14 12.4 4.5 9.3 9 0 0 9 9 9 0 EGF domain DUF4371 PF14291.6 KFM56859.1 - 0.035 13.7 0.0 0.092 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4371) Creatinase_N_2 PF16189.5 KFM56861.1 - 4.6e-44 150.4 0.1 4.4e-43 147.2 0.1 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KFM56861.1 - 1e-39 136.4 0.0 1.8e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KFM56861.1 - 5.8e-20 72.3 0.0 2.2e-17 63.9 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KFM56861.1 - 5.4e-15 55.2 0.4 1.5e-14 53.8 0.4 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 FAM110_C PF14160.6 KFM56862.1 - 0.054 14.6 1.6 0.064 14.3 1.6 1.2 1 0 0 1 1 1 0 Centrosome-associated C terminus DDE_3 PF13358.6 KFM56863.1 - 1.5e-11 44.3 0.0 1.8e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Fib_alpha PF08702.10 KFM56864.1 - 0.032 14.4 6.6 0.021 15.0 4.9 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spore_III_AB PF09548.10 KFM56864.1 - 0.038 14.1 4.3 0.059 13.5 4.3 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) sCache_like PF16736.5 KFM56864.1 - 0.059 13.5 2.5 0.095 12.8 2.5 1.4 1 0 0 1 1 1 0 Single Cache-like HIP1_clath_bdg PF16515.5 KFM56864.1 - 0.063 13.9 10.3 0.11 13.1 10.3 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-RING_9 PF13901.6 KFM56864.1 - 0.15 12.0 8.5 0.21 11.6 3.9 2.0 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon Phage_GPO PF05929.11 KFM56864.1 - 0.23 11.0 5.1 0.16 11.6 3.3 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4239 PF14023.6 KFM56864.1 - 0.25 11.0 3.3 0.33 10.6 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Exonuc_VII_L PF02601.15 KFM56864.1 - 0.78 9.3 6.5 0.88 9.1 6.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5070 PF16802.5 KFM56865.1 - 0.0069 16.4 1.1 0.037 14.0 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5070) Tweety PF04906.13 KFM56865.1 - 0.18 10.4 2.6 2.8 6.5 0.1 2.0 1 1 1 2 2 2 0 Tweety WD40 PF00400.32 KFM56868.1 - 4.8e-24 84.2 14.8 3.1e-05 24.6 0.3 7.2 6 1 1 7 7 7 5 WD domain, G-beta repeat PD40 PF07676.12 KFM56868.1 - 0.00014 21.7 8.2 0.68 10.0 0.1 5.4 5 1 0 5 5 5 2 WD40-like Beta Propeller Repeat SGL PF08450.12 KFM56868.1 - 0.0013 18.4 0.0 0.0042 16.7 0.0 1.8 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 KFM56868.1 - 0.017 14.4 0.0 4.6 6.4 0.0 2.5 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller CRT10 PF08728.10 KFM56868.1 - 0.035 12.3 0.1 0.81 7.8 0.0 2.6 3 0 0 3 3 3 0 CRT10 HTH_Tnp_Tc3_2 PF01498.18 KFM56869.1 - 1.8e-16 60.2 2.2 4e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM56869.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 KFM56870.1 - 2.9e-17 62.9 0.4 3.8e-17 62.6 0.4 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GRDA PF04723.14 KFM56870.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A NCBP3 PF10309.9 KFM56871.1 - 0.00013 21.7 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KFM56871.1 - 0.0067 16.4 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 RNA binding domain zf-H2C2_2 PF13465.6 KFM56873.1 - 8.2e-17 60.8 26.5 5.9e-08 32.8 0.5 4.7 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM56873.1 - 1.7e-14 53.3 23.5 1.9e-05 24.8 0.5 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM56873.1 - 5.2e-06 26.9 20.7 0.0019 18.8 0.4 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFM56873.1 - 0.00041 20.9 3.3 2.2 9.0 0.1 3.2 1 1 2 3 3 3 2 FOXP coiled-coil domain PcF PF09461.10 KFM56873.1 - 0.001 19.4 6.5 1.7 9.1 0.2 3.3 2 1 1 3 3 3 2 Phytotoxin PcF protein zf-C2H2_8 PF15909.5 KFM56873.1 - 0.0028 17.9 4.6 0.021 15.1 0.9 2.2 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 KFM56873.1 - 0.011 16.4 2.0 0.054 14.2 0.5 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats CHORD PF04968.12 KFM56873.1 - 0.07 13.9 12.0 6.5 7.5 0.5 3.2 1 1 2 3 3 3 0 CHORD zf-C2H2_aberr PF17017.5 KFM56873.1 - 0.17 12.0 8.7 33 4.6 8.7 2.9 1 1 0 1 1 1 0 Aberrant zinc-finger zf-met PF12874.7 KFM56873.1 - 0.23 11.9 3.9 25 5.4 0.0 4.1 3 2 0 3 3 3 0 Zinc-finger of C2H2 type DUF629 PF04780.12 KFM56873.1 - 0.24 9.9 4.3 0.65 8.5 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF629) zf-H2C2_5 PF13909.6 KFM56873.1 - 0.26 11.1 0.1 0.26 11.1 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain CxC6 PF18721.1 KFM56873.1 - 1 9.6 9.4 0.82 10.0 3.8 2.5 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases zf-C2H2_6 PF13912.6 KFM56873.1 - 2.3 8.3 10.0 0.39 10.8 2.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Homeodomain PF00046.29 KFM56874.1 - 1.1e-20 73.3 7.0 2.3e-20 72.2 7.0 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFM56874.1 - 0.007 15.8 0.2 0.016 14.7 0.2 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFM56874.1 - 0.017 15.0 0.4 0.042 13.8 0.4 1.6 1 0 0 1 1 1 0 Homeobox KN domain Flu_NS2 PF00601.19 KFM56874.1 - 0.079 13.3 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) DUF515 PF04415.12 KFM56874.1 - 5.2 5.4 9.8 8.4 4.7 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Homeodomain PF00046.29 KFM56875.1 - 2.9e-21 75.1 3.8 4.5e-21 74.5 3.8 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFM56875.1 - 0.013 15.0 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFM56875.1 - 0.015 15.2 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain DNA_photolyase PF00875.18 KFM56875.1 - 0.015 15.3 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 DNA photolyase DUF1525 PF07511.11 KFM56875.1 - 0.14 12.3 0.6 0.19 11.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) FliG_C PF01706.16 KFM56875.1 - 0.15 12.3 0.1 0.19 11.9 0.1 1.1 1 0 0 1 1 1 0 FliG C-terminal domain Homeodomain PF00046.29 KFM56877.1 - 1.3e-20 73.0 6.7 3.9e-20 71.5 6.7 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM56877.1 - 0.047 13.6 2.6 0.17 11.8 0.1 3.0 3 0 0 3 3 3 0 Homeobox KN domain Homez PF11569.8 KFM56877.1 - 0.13 11.7 0.4 0.85 9.1 0.2 2.2 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez DUF1627 PF07789.12 KFM56877.1 - 0.32 10.6 3.9 0.27 10.9 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1627) Homeodomain PF00046.29 KFM56879.1 - 8.7e-22 76.7 5.9 8.7e-22 76.7 5.9 1.5 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFM56879.1 - 0.081 12.8 1.0 0.27 11.2 0.4 2.0 2 0 0 2 2 2 0 Homeobox KN domain Homez PF11569.8 KFM56879.1 - 0.24 10.9 2.4 0.28 10.7 0.2 2.3 2 1 1 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Glyco_hydro_63 PF03200.16 KFM56880.1 - 1.8e-207 690.0 3.0 2.3e-207 689.6 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KFM56880.1 - 1.9e-41 142.6 0.5 1.9e-41 142.6 0.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 KFM56880.1 - 0.0015 17.5 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Mfa_like_2 PF15415.6 KFM56880.1 - 0.078 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Fimbrillin-like DDRGK PF09756.9 KFM56881.1 - 7.9e-62 208.2 37.2 1.1e-61 207.7 37.2 1.2 1 0 0 1 1 1 1 DDRGK domain FeoC PF09012.10 KFM56881.1 - 0.0082 16.2 0.8 5.3 7.2 0.1 2.8 3 0 0 3 3 3 2 FeoC like transcriptional regulator Rrn6 PF10214.9 KFM56881.1 - 0.023 13.2 8.5 0.029 12.9 8.5 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3347 PF11827.8 KFM56881.1 - 0.13 12.5 10.4 0.18 12.0 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) FAM76 PF16046.5 KFM56881.1 - 0.24 10.7 14.4 0.33 10.3 14.4 1.2 1 0 0 1 1 1 0 FAM76 protein Asp-B-Hydro_N PF05279.11 KFM56881.1 - 0.34 10.9 23.0 0.42 10.6 23.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pox_Ag35 PF03286.14 KFM56881.1 - 1 9.1 31.0 3.3 7.5 31.0 1.8 1 1 0 1 1 1 0 Pox virus Ag35 surface protein CRT10 PF08728.10 KFM56881.1 - 1.9 6.5 6.7 2.4 6.2 6.7 1.1 1 0 0 1 1 1 0 CRT10 AAA_11 PF13086.6 KFM56881.1 - 2.8 7.6 10.9 4 7.2 10.9 1.4 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 KFM56881.1 - 4 7.2 20.6 6 6.6 20.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 XRN_M PF17846.1 KFM56881.1 - 9.3 5.1 17.4 13 4.6 17.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Colicin_M PF14859.6 KFM56882.1 - 0.039 13.1 0.1 0.051 12.7 0.1 1.1 1 0 0 1 1 1 0 Colicin M PAN_1 PF00024.26 KFM56883.1 - 0.00068 19.5 0.4 0.0016 18.4 0.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KFM56883.1 - 0.017 15.0 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 PAN domain Colicin_M PF14859.6 KFM56883.1 - 0.14 11.2 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Colicin M HTH_Tnp_Tc3_2 PF01498.18 KFM56884.1 - 3.7e-16 59.1 6.8 6.2e-16 58.4 6.8 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM56884.1 - 1.8e-14 53.8 0.1 1.9e-13 50.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM56884.1 - 0.0025 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KFM56884.1 - 0.0082 16.7 0.7 0.0082 16.7 0.7 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM56884.1 - 0.016 15.3 0.1 0.063 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM56884.1 - 0.024 14.7 1.7 0.036 14.1 0.2 2.0 2 0 0 2 2 2 0 Winged helix-turn helix Aldedh PF00171.22 KFM56888.1 - 1.6e-129 432.5 0.0 1.7e-129 432.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DDE_3 PF13358.6 KFM56889.1 - 1.5e-07 31.3 0.0 1.6e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM56890.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM56890.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease TetR_C_7 PF14246.6 KFM56891.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain Y_phosphatase PF00102.27 KFM56892.1 - 1.9e-58 197.8 0.3 3.6e-58 196.9 0.3 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.10 KFM56892.1 - 7.9e-10 39.0 0.5 1.7e-09 37.9 0.5 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DSPc PF00782.20 KFM56892.1 - 0.00011 22.0 0.1 0.00034 20.4 0.1 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Carb_bind PF10645.9 KFM56892.1 - 0.091 13.0 0.8 0.25 11.6 0.8 1.7 1 0 0 1 1 1 0 Carbohydrate binding FERM_M PF00373.18 KFM56893.1 - 8.9e-22 77.7 0.6 1.4e-21 77.1 0.6 1.3 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFM56893.1 - 1.1e-18 66.9 0.1 2.1e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain Cation_efflux PF01545.21 KFM56894.1 - 4.9e-54 183.1 9.1 6e-54 182.8 9.1 1.1 1 0 0 1 1 1 1 Cation efflux family T4SS_CagC PF16943.5 KFM56894.1 - 0.072 13.3 2.1 2.4 8.4 0.1 2.6 2 1 0 2 2 2 0 Cag pathogenicity island, type IV secretory system ArAE_1 PF06081.11 KFM56894.1 - 1.1 9.4 9.4 0.087 13.0 2.1 2.3 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 Chromate_transp PF02417.15 KFM56894.1 - 8 6.6 12.1 11 6.2 5.5 2.3 2 0 0 2 2 2 0 Chromate transporter Metal_hydrol PF10118.9 KFM56894.1 - 8.1 6.1 7.7 0.38 10.4 0.1 2.4 3 0 0 3 3 3 0 Predicted metal-dependent hydrolase NPCC PF08058.11 KFM56894.1 - 8.2 6.5 6.2 2.9 8.0 1.1 2.3 2 1 0 2 2 2 0 Nuclear pore complex component HTH_Tnp_Tc3_2 PF01498.18 KFM56895.1 - 2.4e-13 50.1 0.1 3.6e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM56895.1 - 0.00029 21.4 0.7 0.00029 21.4 0.7 2.0 2 0 0 2 2 2 1 Homeodomain-like domain Choline_kinase PF01633.20 KFM56897.1 - 5e-72 241.9 0.0 6.1e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFM56897.1 - 9.6e-11 42.1 0.0 1.7e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFM56897.1 - 0.0015 17.9 0.1 0.0038 16.6 0.1 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Rsbr_N PF08678.10 KFM56898.1 - 0.0054 16.8 0.1 0.0094 16.0 0.1 1.4 1 1 0 1 1 1 1 Rsbr N terminal SUV3_C PF12513.8 KFM56898.1 - 0.21 11.5 1.1 14 5.7 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal DDE_Tnp_1_7 PF13843.6 KFM56900.1 - 0.00075 18.9 0.0 0.00089 18.7 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_7 PF13843.6 KFM56901.1 - 2.2e-15 56.8 0.2 2.5e-15 56.7 0.2 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_1 PF03184.19 KFM56902.1 - 0.037 13.7 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Piwi PF02171.17 KFM56903.1 - 1.2e-16 60.8 0.0 1.4e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Piwi domain Piwi PF02171.17 KFM56904.1 - 4.6e-15 55.6 0.6 6.7e-15 55.1 0.6 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KFM56904.1 - 1.7e-05 25.0 0.1 6.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL1 PF08699.10 KFM56905.1 - 1.2e-23 82.5 0.1 2.1e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KFM56905.1 - 1.1e-15 57.6 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KFM56905.1 - 2.2e-11 44.5 0.0 4.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ABC_membrane PF00664.23 KFM56907.1 - 1.7e-59 201.8 8.9 2.4e-59 201.3 8.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFM56907.1 - 2.4e-35 122.0 0.3 5.4e-35 120.9 0.0 1.8 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 KFM56907.1 - 1.3e-08 34.6 0.3 2.7e-07 30.2 0.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KFM56907.1 - 5.9e-05 22.1 0.0 0.00018 20.5 0.0 1.7 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 KFM56907.1 - 0.00036 20.8 0.0 0.002 18.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM56907.1 - 0.00041 20.8 0.1 0.0012 19.3 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFM56907.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KFM56907.1 - 0.0097 15.8 0.1 0.065 13.2 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 KFM56907.1 - 0.011 15.5 0.5 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 KFM56907.1 - 0.027 14.7 0.5 0.36 11.1 0.5 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KFM56907.1 - 0.029 14.8 0.1 0.42 11.0 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFM56907.1 - 0.032 14.0 0.5 0.17 11.6 0.0 2.4 2 1 0 2 2 1 0 AAA domain AAA_15 PF13175.6 KFM56907.1 - 0.059 13.1 0.3 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 KFM56907.1 - 0.082 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_21 PF13304.6 KFM56907.1 - 0.1 12.4 0.0 15 5.3 0.0 2.4 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KFM56907.1 - 0.11 12.4 0.0 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KFM56907.1 - 0.12 11.7 0.1 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin ECF_trnsprt PF12822.7 KFM56907.1 - 3 7.9 9.9 3.2 7.8 8.4 1.6 1 1 0 1 1 1 0 ECF transporter, substrate-specific component ABC_membrane PF00664.23 KFM56908.1 - 1.6e-67 228.1 4.1 1.8e-67 227.9 4.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region TMEM189_B_dmain PF10520.9 KFM56908.1 - 0.0088 16.2 0.5 0.0088 16.2 0.5 1.7 2 0 0 2 2 2 1 B domain of TMEM189, localisation domain AWPM-19 PF05512.11 KFM56908.1 - 0.084 13.1 0.5 0.084 13.1 0.5 2.8 3 0 0 3 3 3 0 AWPM-19-like family PMT_4TMC PF16192.5 KFM56908.1 - 0.37 10.3 7.4 0.38 10.3 0.4 2.5 2 1 0 3 3 3 0 C-terminal four TMM region of protein-O-mannosyltransferase 14-3-3 PF00244.20 KFM56910.1 - 2e-107 357.8 5.4 2.3e-107 357.6 5.4 1.0 1 0 0 1 1 1 1 14-3-3 protein PhoU_div PF01865.16 KFM56910.1 - 0.031 13.6 0.3 0.17 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF47 FliM PF02154.15 KFM56910.1 - 0.07 13.0 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Kringle PF00051.18 KFM56912.1 - 1.1e-10 41.6 2.7 2.2e-10 40.7 2.7 1.4 1 0 0 1 1 1 1 Kringle domain MLANA PF14991.6 KFM56912.1 - 0.03 14.6 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A LRR19-TM PF15176.6 KFM56912.1 - 0.034 14.1 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4381 PF14316.6 KFM56912.1 - 0.093 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Rax2 PF12768.7 KFM56912.1 - 0.18 11.2 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Pkinase_Tyr PF07714.17 KFM56913.1 - 5.4e-63 212.7 0.0 6.1e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM56913.1 - 4.2e-24 85.3 0.0 5.3e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFM56913.1 - 0.012 14.9 0.2 0.052 12.9 0.2 1.8 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KFM56913.1 - 0.058 12.3 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain EB PF01683.18 KFM56914.1 - 0.00012 22.3 4.7 0.00022 21.4 4.7 1.5 1 0 0 1 1 1 1 EB module DUF4366 PF14283.6 KFM56914.1 - 0.1 12.7 0.1 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) TOM6p PF15184.6 KFM56915.1 - 0.038 13.8 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog HPTransfase PF10090.9 KFM56919.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain zf-C2H2 PF00096.26 KFM56920.1 - 4.1e-32 108.8 86.9 2.1e-05 24.7 0.1 9.6 10 0 0 10 10 9 9 Zinc finger, C2H2 type zf-met PF12874.7 KFM56920.1 - 2.1e-28 97.8 62.7 5.8e-05 23.3 0.2 9.8 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM56920.1 - 1.5e-27 93.9 76.1 0.00081 20.0 0.3 9.5 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM56920.1 - 1.1e-26 91.9 86.0 2.6e-06 27.6 0.1 11.1 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM56920.1 - 1.9e-18 66.2 53.4 0.00032 20.9 0.3 9.6 9 0 0 9 9 9 8 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM56920.1 - 0.00021 21.5 23.3 0.45 10.8 3.3 6.8 1 1 4 5 5 5 1 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM56920.1 - 0.0027 17.7 38.5 0.7 10.0 1.4 8.8 8 1 1 9 9 9 1 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 KFM56920.1 - 0.007 16.3 0.7 0.1 12.6 0.1 9.3 9 1 0 9 9 9 2 C2H2-type zinc finger UPF0728 PF15092.6 KFM56920.1 - 0.26 11.2 7.9 0.63 9.9 0.2 4.4 3 2 0 4 4 4 0 Uncharacterised protein family UPF0728 Zn_ribbon_SprT PF17283.2 KFM56920.1 - 1.2 9.2 42.3 2.4 8.1 0.0 6.6 5 1 0 6 6 6 0 SprT-like zinc ribbon domain zf-C2H2_9 PF16293.5 KFM56920.1 - 2.2 8.2 42.1 1.4 8.8 0.5 8.4 6 2 3 9 9 9 0 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 KFM56920.1 - 3.7 7.9 46.2 0.79 10.1 1.7 4.9 2 2 3 5 5 5 0 C2H2-type zinc ribbon zinc-ribbons_6 PF07191.12 KFM56920.1 - 6.7 6.8 48.3 9.2 6.3 1.8 7.9 2 2 4 6 6 5 0 zinc-ribbons SHMT PF00464.19 KFM56921.1 - 1.5e-199 662.6 0.0 1.8e-199 662.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KFM56921.1 - 0.00016 21.0 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Nif11 PF07862.11 KFM56921.1 - 0.002 18.4 1.0 0.0046 17.2 0.1 2.1 3 0 0 3 3 3 1 Nif11 domain MRP-S31 PF15433.6 KFM56923.1 - 1.2e-74 251.9 0.8 1.3e-74 251.7 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 IMS PF00817.20 KFM56925.1 - 2e-14 53.8 0.0 2.3e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 impB/mucB/samB family CxxCxxCC PF03692.15 KFM56925.1 - 0.0061 17.2 0.0 0.0061 17.2 0.0 1.1 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain TfoX_N PF04993.13 KFM56925.1 - 0.0068 16.6 0.0 0.0075 16.5 0.0 1.0 1 0 0 1 1 1 1 TfoX N-terminal domain zf_UBZ PF18439.1 KFM56926.1 - 3e-13 49.1 0.7 6.8e-13 48.0 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger CooC_C PF15976.5 KFM56926.1 - 0.046 13.8 0.1 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 CS1-pili formation C-terminal RhoGAP PF00620.27 KFM56928.1 - 2.3e-29 102.2 0.0 2.6e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain DUF3220 PF11516.8 KFM56928.1 - 0.077 13.2 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) HTH_Tnp_Tc3_2 PF01498.18 KFM56929.1 - 4.4e-16 58.9 2.2 4.4e-16 58.9 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM56929.1 - 9.6e-14 51.4 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM56930.1 - 3.9e-16 59.0 3.5 5.8e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM56930.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM56930.1 - 2e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM56930.1 - 0.0025 17.5 0.6 0.0077 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM56930.1 - 2 9.1 15.6 0.12 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM56931.1 - 1.2e-11 44.6 4.1 2.7e-11 43.6 4.1 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM56931.1 - 4.1e-07 29.9 0.1 2.3e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM56931.1 - 2.1 9.0 11.0 0.082 13.5 1.8 2.8 1 1 1 2 2 2 0 Homeodomain-like domain Ras PF00071.22 KFM56932.1 - 5.6e-50 169.1 0.0 6.3e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM56932.1 - 4.2e-27 94.7 0.0 5.4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM56932.1 - 4.4e-10 39.3 0.0 5.1e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM56932.1 - 7.5e-05 22.8 0.0 9.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM56932.1 - 0.029 13.7 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 KFM56932.1 - 0.038 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 KFM56932.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFM56932.1 - 0.11 12.4 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase WAP PF00095.21 KFM56933.1 - 7.9e-11 42.2 13.3 1.1e-10 41.8 13.3 1.2 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Oxidored-like PF09791.9 KFM56933.1 - 9.9 5.9 11.1 7.9 6.2 6.4 2.3 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal YL1 PF05764.13 KFM56934.1 - 0.28 11.3 3.7 0.31 11.1 3.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Pkinase PF00069.25 KFM56935.1 - 3.6e-56 190.5 0.0 4.8e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM56935.1 - 5e-22 78.4 0.0 7.9e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM56935.1 - 2.6e-06 27.5 0.0 0.0013 18.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KFM56935.1 - 0.0036 16.9 3.1 0.0036 16.9 3.1 2.0 2 1 0 2 2 2 1 RIO1 family Kelch_2 PF07646.15 KFM56935.1 - 0.0043 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Kelch motif Choline_kinase PF01633.20 KFM56935.1 - 0.02 14.5 0.1 0.045 13.3 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KFM56935.1 - 0.078 12.3 0.5 0.12 11.7 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MRG PF05712.13 KFM56935.1 - 0.081 12.2 0.7 0.34 10.2 0.0 2.1 2 1 0 3 3 3 0 MRG YrbL-PhoP_reg PF10707.9 KFM56935.1 - 0.09 12.3 5.7 0.095 12.2 0.1 2.3 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL ABC1 PF03109.16 KFM56935.1 - 0.16 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 ABC1 family DDE_3 PF13358.6 KFM56936.1 - 8.7e-15 54.8 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM56936.1 - 1.3e-10 41.3 1.0 2.1e-10 40.7 1.0 1.4 1 0 0 1 1 1 1 Transposase MFS_1 PF07690.16 KFM56937.1 - 0.002 17.1 28.2 0.0024 16.9 14.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2244 PF10003.9 KFM56937.1 - 0.57 9.9 0.0 0.57 9.9 0.0 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4345 PF14248.6 KFM56937.1 - 2.6 8.0 14.5 0.027 14.4 5.0 2.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4345) DUF2070 PF09843.9 KFM56937.1 - 4.5 5.4 12.1 6.4 4.9 12.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DDE_3 PF13358.6 KFM56938.1 - 9e-12 45.0 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Dus PF01207.17 KFM56940.1 - 5.7e-32 111.0 0.0 6.7e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Arm PF00514.23 KFM56942.1 - 3.8e-87 284.0 17.1 3.9e-12 45.8 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFM56942.1 - 2.1e-22 79.3 4.0 1e-21 77.2 4.1 2.1 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 KFM56942.1 - 1e-21 76.2 1.6 2.8e-21 74.8 1.4 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFM56942.1 - 1.4e-18 66.9 4.4 1.5e-06 28.6 0.0 6.1 4 3 3 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 KFM56942.1 - 1.5e-15 57.4 0.0 0.00026 21.3 0.0 6.2 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.22 KFM56942.1 - 3.7e-10 39.2 8.4 0.022 15.0 0.0 7.4 9 0 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.20 KFM56942.1 - 7.7e-05 21.4 0.3 0.21 10.1 0.3 3.3 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 KFM56942.1 - 0.0001 22.4 0.0 3.4 7.8 0.0 4.1 5 0 0 5 5 5 1 V-ATPase subunit H DUF3384 PF11864.8 KFM56942.1 - 0.022 13.7 0.1 0.38 9.6 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3384) Arm_2 PF04826.13 KFM56942.1 - 0.029 13.9 1.0 15 5.0 0.1 3.7 2 2 1 3 3 3 0 Armadillo-like UQ_con PF00179.26 KFM56943.1 - 3.4e-46 156.4 0.2 3.9e-46 156.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFM56943.1 - 4.7e-05 23.2 0.1 8.6e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 UEV domain RWD PF05773.22 KFM56943.1 - 6.7e-05 23.1 0.0 9.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFM56943.1 - 0.00033 20.4 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF1154 PF06631.11 KFM56943.1 - 0.043 13.8 5.1 3 7.9 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) HTH_Tnp_Tc3_2 PF01498.18 KFM56944.1 - 2e-16 60.0 2.2 7e-16 58.2 2.2 2.0 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM56944.1 - 2.7e-16 59.6 0.1 2.9e-13 49.8 0.0 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_38 PF13936.6 KFM56944.1 - 3.5e-07 29.9 1.6 8.3e-07 28.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM56944.1 - 0.003 17.3 0.5 0.009 15.8 0.5 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM56944.1 - 3.1 8.5 15.6 0.15 12.7 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain VWC PF00093.18 KFM56945.1 - 0.0063 16.8 14.7 0.0063 16.8 14.7 3.5 3 1 1 4 4 4 2 von Willebrand factor type C domain VWC PF00093.18 KFM56946.1 - 0.81 10.1 16.0 1.4 9.3 16.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain VWC PF00093.18 KFM56947.1 - 1.3e-07 31.8 18.8 0.00029 21.1 1.6 2.3 2 0 0 2 2 2 2 von Willebrand factor type C domain Pacifastin_I PF05375.13 KFM56947.1 - 0.016 15.0 7.3 0.64 9.8 0.2 2.5 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) TILa PF12714.7 KFM56947.1 - 0.14 12.1 20.4 0.24 11.4 2.9 2.9 2 1 1 3 3 3 0 TILa domain VGCC_beta4Aa_N PF12052.8 KFM56947.1 - 0.18 11.9 0.8 0.41 10.8 0.8 1.6 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal CFC PF09443.10 KFM56947.1 - 1.5 8.7 15.1 2.2 8.2 3.6 2.5 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) VWC PF00093.18 KFM56948.1 - 2.2e-15 56.7 79.0 3.2e-05 24.2 13.4 5.3 5 0 0 5 5 5 5 von Willebrand factor type C domain ERp29_N PF07912.13 KFM56949.1 - 2.5e-36 124.6 0.5 4.3e-36 123.8 0.5 1.4 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.12 KFM56949.1 - 2e-15 57.4 0.3 4.4e-15 56.4 0.3 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin PF00085.20 KFM56949.1 - 0.018 15.1 0.2 0.061 13.3 0.2 2.0 1 1 0 1 1 1 0 Thioredoxin FmdE PF02663.14 KFM56949.1 - 0.3 11.1 1.4 1 9.4 1.0 2.1 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon QIL1 PF15884.5 KFM56950.1 - 0.12 13.0 0.0 7 7.3 0.0 2.1 1 1 1 2 2 2 0 MICOS complex subunit MIC13, QIL1 DOT1 PF08123.13 KFM56951.1 - 3.2e-13 49.7 0.0 3.4e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Histone methylation protein DOT1 H-kinase_dim PF02895.14 KFM56952.1 - 0.021 15.2 0.6 0.025 15.0 0.6 1.1 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DivIC PF04977.15 KFM56952.1 - 0.039 13.7 0.7 0.045 13.5 0.7 1.1 1 0 0 1 1 1 0 Septum formation initiator DUF2371 PF10177.9 KFM56957.1 - 0.00072 19.7 0.0 0.00072 19.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) LMBR1 PF04791.16 KFM56959.1 - 5e-37 128.0 4.5 5.9e-37 127.7 4.5 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein RNase_H PF00075.24 KFM56960.1 - 9.7e-05 22.6 0.0 0.00021 21.5 0.0 1.6 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM56960.1 - 0.00026 20.8 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Transposase_1 PF01359.18 KFM56961.1 - 0.086 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Transposase (partial DDE domain) LMBR1 PF04791.16 KFM56962.1 - 5.2e-09 35.6 0.3 5.2e-09 35.6 0.3 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein LRR_8 PF13855.6 KFM56965.1 - 5.3e-62 205.5 60.1 6.1e-12 45.1 4.3 8.5 3 3 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFM56965.1 - 1.1e-35 121.0 52.3 1.4e-06 28.6 2.7 9.6 5 3 3 10 10 10 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM56965.1 - 2.4e-23 82.5 14.5 1.1e-08 35.1 0.9 3.8 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM56965.1 - 9.7e-15 54.5 23.2 2.6e-05 23.8 1.9 4.4 2 1 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFM56965.1 - 7.9e-09 34.9 46.1 0.34 11.6 0.1 12.7 13 2 0 13 13 13 4 Leucine Rich Repeat LRR_6 PF13516.6 KFM56965.1 - 0.00044 20.1 48.4 3.3 8.0 1.0 13.2 14 0 0 14 14 14 4 Leucine Rich repeat LRR_2 PF07723.13 KFM56965.1 - 0.89 10.3 10.6 96 3.9 0.2 5.8 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 KFM56966.1 - 5.4e-05 22.9 2.2 6.1e-05 22.7 0.1 2.3 2 1 1 3 3 3 1 Leucine rich repeat LRRCT PF01463.24 KFM56966.1 - 0.0017 18.7 0.0 0.0075 16.7 0.0 2.2 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Protocadherin PF08374.11 KFM56966.1 - 0.022 14.7 0.2 0.039 13.9 0.2 1.3 1 0 0 1 1 1 0 Protocadherin Adeno_E3_CR2 PF02439.15 KFM56966.1 - 2 8.3 14.1 3.7 7.4 14.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kazal_2 PF07648.15 KFM56969.1 - 1.9e-10 40.7 39.5 1e-06 28.7 4.8 5.1 4 1 1 5 5 5 3 Kazal-type serine protease inhibitor domain VWC PF00093.18 KFM56969.1 - 0.0007 19.9 11.4 0.0007 19.9 11.4 6.9 5 1 1 6 6 6 2 von Willebrand factor type C domain Kazal_1 PF00050.21 KFM56969.1 - 0.0012 18.8 12.9 0.0022 18.0 5.9 5.7 5 1 0 6 6 6 3 Kazal-type serine protease inhibitor domain TILa PF12714.7 KFM56969.1 - 0.017 15.1 10.4 0.017 15.1 10.4 5.8 4 3 2 6 6 6 0 TILa domain DDE_Tnp_1_7 PF13843.6 KFM56971.1 - 8.8e-12 45.0 0.0 9.6e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 zf-H2C2_2 PF13465.6 KFM56972.1 - 9.7e-79 256.6 96.5 5.7e-10 39.2 1.2 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM56972.1 - 1.1e-56 186.3 108.9 1.9e-05 24.8 1.9 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM56972.1 - 8.7e-48 156.8 102.5 0.00048 20.7 2.0 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM56972.1 - 1e-23 83.0 90.1 0.028 14.8 0.3 12.4 11 1 1 12 12 12 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM56972.1 - 3.7e-21 74.9 71.5 0.0061 16.8 0.2 12.3 12 0 0 12 12 12 11 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM56972.1 - 2.6e-19 69.3 11.8 0.004 17.4 0.4 8.4 1 1 5 6 6 6 5 BolA-like protein zf-C2H2_6 PF13912.6 KFM56972.1 - 8.9e-19 67.0 82.5 0.072 13.1 0.1 13.1 12 1 0 12 12 12 11 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM56972.1 - 2.2e-07 30.6 50.3 3.2 7.7 0.0 11.9 12 0 0 12 12 12 3 zinc-finger of a C2HC-type Baculo_IE-1 PF05290.11 KFM56972.1 - 0.00018 21.5 38.1 2.1 8.3 0.7 9.6 1 1 6 8 8 8 3 Baculovirus immediate-early protein (IE-0) BHD_1 PF10403.9 KFM56972.1 - 0.00027 20.7 4.1 0.65 9.9 0.0 5.9 7 1 0 7 7 7 1 Rad4 beta-hairpin domain 1 Zf_RING PF16744.5 KFM56972.1 - 0.00033 20.7 47.3 4.6 7.4 0.2 10.7 1 1 9 11 11 11 1 KIAA1045 RING finger Ta0938 PF11494.8 KFM56972.1 - 0.00057 20.1 27.7 0.74 10.1 0.3 7.7 1 1 7 8 8 8 2 Ta0938 zf-C2H2_11 PF16622.5 KFM56972.1 - 0.0042 16.8 62.9 0.47 10.3 0.0 11.1 12 0 0 12 12 12 5 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM56972.1 - 0.0085 15.8 97.4 0.016 15.0 2.3 12.4 12 1 0 12 12 12 7 C2H2-type zinc-finger domain TRAF6_Z2 PF18048.1 KFM56972.1 - 0.081 13.0 0.4 0.081 13.0 0.4 8.7 10 0 0 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 XPA_N PF01286.18 KFM56972.1 - 0.26 11.4 50.0 3.4 7.8 0.1 11.5 12 0 0 12 12 12 0 XPA protein N-terminal zf-C2H2_2 PF12756.7 KFM56972.1 - 0.59 10.5 72.1 3.3 8.1 6.0 9.5 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM56972.1 - 1.2 9.4 44.1 3.6 7.8 0.1 10.7 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) Scramblase PF03803.15 KFM56972.1 - 1.7 7.9 9.0 0.43 9.9 0.2 3.0 1 1 1 3 3 3 0 Scramblase zinc_ribbon_15 PF17032.5 KFM56972.1 - 4.7 8.0 46.7 14 6.6 0.3 6.7 3 2 4 8 8 8 0 zinc-ribbon family GAGA PF09237.11 KFM56972.1 - 5.5 6.9 21.5 14 5.6 0.1 7.3 4 3 5 9 9 8 0 GAGA factor HTH_Tnp_Tc3_2 PF01498.18 KFM56973.1 - 3.1e-14 52.9 1.0 5.8e-14 52.1 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM56973.1 - 7.8e-14 51.7 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM56974.1 - 4.6e-16 58.8 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM56974.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM56974.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM56974.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM56974.1 - 6.6 7.4 17.6 0.12 13.0 1.9 3.4 3 1 1 4 4 4 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM56975.1 - 2.5e-16 59.7 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM56975.1 - 9.7e-14 51.3 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Caskin1-CID PF16600.5 KFM56976.1 - 3.5 8.3 17.3 15 6.3 0.6 2.6 2 1 0 2 2 2 0 Caskin1 CASK-interaction domain HTH_Tnp_Tc3_2 PF01498.18 KFM56978.1 - 6.8e-16 58.3 2.2 6.8e-16 58.3 2.2 2.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM56978.1 - 1.3e-13 51.0 0.0 2.8e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM56978.1 - 3.5e-07 29.9 0.2 2.3e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM56978.1 - 0.0038 17.0 0.2 0.01 15.6 0.2 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Bac_DnaA_C PF08299.11 KFM56978.1 - 0.013 15.5 0.2 0.044 13.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix Sigma70_r4 PF04545.16 KFM56978.1 - 0.084 12.4 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 fn3 PF00041.21 KFM56979.1 - 1.4e-07 31.8 0.0 3.9e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain RA PF00788.23 KFM56979.1 - 0.00096 19.7 0.0 0.0056 17.3 0.0 2.3 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ank_4 PF13637.6 KFM56979.1 - 0.0059 17.2 0.0 0.033 14.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Frtz PF11768.8 KFM56979.1 - 0.038 12.3 0.0 0.066 11.5 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Thioredoxin_6 PF13848.6 KFM56981.1 - 3.7e-46 157.4 6.3 1.5e-39 135.8 5.7 2.4 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFM56981.1 - 6.6e-36 122.4 0.5 2.1e-32 111.2 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Calsequestrin PF01216.17 KFM56981.1 - 8.6e-11 41.5 7.9 1.2e-10 41.0 7.9 1.2 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 KFM56981.1 - 1.5e-08 35.0 0.3 2.9e-06 27.7 0.0 3.0 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFM56981.1 - 8.4e-07 29.1 0.0 3.3e-05 24.0 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like OST3_OST6 PF04756.13 KFM56981.1 - 9.2e-06 25.2 0.0 0.00019 20.9 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFM56981.1 - 0.00028 20.8 0.5 0.027 14.4 0.0 3.1 3 1 0 4 4 4 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFM56981.1 - 0.0021 18.4 0.7 1.1 9.7 0.0 3.6 2 1 0 3 3 3 1 Thioredoxin-like HyaE PF07449.11 KFM56981.1 - 0.009 16.0 0.0 1 9.3 0.0 3.3 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE NIBRIN_BRCT_II PF16508.5 KFM56981.1 - 0.015 15.6 0.0 0.1 12.9 0.0 2.1 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein Redoxin PF08534.10 KFM56981.1 - 0.044 13.5 0.6 0.76 9.5 0.0 2.8 3 1 0 3 3 3 0 Redoxin Thioredoxin_4 PF13462.6 KFM56981.1 - 0.051 13.7 0.6 0.77 9.9 0.1 2.7 2 1 1 3 3 3 0 Thioredoxin HTH_Tnp_Tc3_2 PF01498.18 KFM56983.1 - 1.7e-13 50.6 3.1 2e-13 50.3 3.1 1.1 1 0 0 1 1 1 1 Transposase NHL PF01436.21 KFM56989.1 - 9.4e-25 85.4 11.3 6.3e-07 29.1 0.0 6.2 6 0 0 6 6 6 4 NHL repeat zf-B_box PF00643.24 KFM56989.1 - 4.3e-09 36.4 30.9 9.4e-07 28.9 14.6 4.2 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 KFM56989.1 - 5.3e-06 26.2 10.9 5.3e-06 26.2 10.9 3.6 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM56989.1 - 9.3e-06 25.6 6.5 9.3e-06 25.6 6.5 2.8 2 1 0 2 2 2 1 RING-type zinc-finger DUF5128 PF17170.4 KFM56989.1 - 5.8e-05 22.4 1.5 0.15 11.2 0.3 3.2 2 1 1 3 3 3 2 6-bladed beta-propeller zf-RING_5 PF14634.6 KFM56989.1 - 0.00019 21.3 9.0 0.00019 21.3 9.0 4.0 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM56989.1 - 0.00058 19.7 10.1 0.00058 19.7 10.1 3.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM56989.1 - 0.0015 18.4 7.3 0.0015 18.4 7.3 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM56989.1 - 0.0019 18.0 8.1 0.0019 18.0 8.1 3.7 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 SGL PF08450.12 KFM56989.1 - 0.0022 17.6 0.1 21 4.6 0.0 3.9 3 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region zf-RING_2 PF13639.6 KFM56989.1 - 0.0025 18.1 8.8 0.0025 18.1 8.8 3.8 3 0 0 3 3 2 1 Ring finger domain P4Ha_N PF08336.11 KFM56989.1 - 0.54 10.3 4.2 1 9.4 4.2 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CdvA PF18822.1 KFM56989.1 - 1 9.2 7.8 1.9 8.3 7.8 1.4 1 0 0 1 1 1 0 CdvA-like coiled-coil domain GCFC PF07842.12 KFM56990.1 - 3e-89 299.3 22.7 2.1e-88 296.5 21.4 2.2 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KFM56990.1 - 6.7e-10 38.7 1.5 1.2e-09 37.9 1.5 1.4 1 0 0 1 1 1 1 G-patch domain DUF2433 PF10360.9 KFM56990.1 - 0.091 12.9 1.5 0.48 10.5 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) DUF1415 PF07209.12 KFM56990.1 - 0.093 12.5 1.0 0.24 11.2 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) Pro_isomerase PF00160.21 KFM56991.1 - 4.4e-53 179.8 0.2 5.5e-53 179.5 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DDE_Tnp_1_7 PF13843.6 KFM56992.1 - 3.8e-17 62.6 0.7 4.2e-17 62.5 0.7 1.0 1 0 0 1 1 1 1 Transposase IS4 Mito_carr PF00153.27 KFM56993.1 - 1.2e-49 166.1 5.8 8.8e-16 57.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3147 PF11345.8 KFM56993.1 - 0.29 11.5 3.8 5.4 7.4 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3147) DEAD PF00270.29 KFM56994.1 - 1.9e-31 109.2 0.0 3.4e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM56994.1 - 5.9e-24 84.6 0.0 2.5e-23 82.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM56994.1 - 0.0008 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KFM56994.1 - 0.057 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Tetraspanin PF00335.20 KFM56996.1 - 3.7e-12 46.5 0.1 4e-12 46.4 0.1 1.0 1 0 0 1 1 1 1 Tetraspanin family Aa_trans PF01490.18 KFM56998.1 - 5.5e-51 173.6 5.3 6e-51 173.4 5.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KFM57000.1 - 9.8e-11 41.0 0.2 1.2e-10 40.8 0.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-H2C2_2 PF13465.6 KFM57001.1 - 1e-93 303.9 86.5 5.1e-09 36.2 0.2 15.5 16 0 0 16 16 16 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57001.1 - 9.8e-58 189.5 119.6 8.9e-06 25.9 2.1 14.7 15 0 0 15 15 15 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57001.1 - 1.7e-39 131.1 114.2 0.0018 19.0 1.7 14.3 15 0 0 15 15 14 13 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM57001.1 - 6.3e-19 67.5 80.5 2e-05 24.5 0.8 13.9 13 0 0 13 13 13 9 C2H2-type zinc finger zf-met PF12874.7 KFM57001.1 - 6.2e-15 55.0 94.0 0.0068 16.8 0.2 13.4 13 0 0 13 13 13 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM57001.1 - 2.9e-11 43.4 71.0 0.035 14.4 0.1 13.3 13 0 0 13 13 13 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM57001.1 - 8.6e-11 41.4 75.9 0.015 15.1 0.3 13.6 13 0 0 13 13 13 8 C2H2-type zinc-finger domain GAGA PF09237.11 KFM57001.1 - 3.4e-10 39.6 43.7 0.25 11.2 0.1 11.3 3 2 10 13 13 13 6 GAGA factor BolA PF01722.18 KFM57001.1 - 1.2e-05 25.5 21.3 1.1 9.6 0.3 8.9 2 2 7 10 10 10 2 BolA-like protein ADK_lid PF05191.14 KFM57001.1 - 0.00015 21.6 38.3 0.65 10.0 0.8 8.2 6 3 0 6 6 6 3 Adenylate kinase, active site lid DUF4825 PF16107.5 KFM57001.1 - 0.0012 19.0 0.1 63 3.8 0.0 5.8 3 1 4 7 7 7 0 Domain of unknown function (DUF4825) zf-Sec23_Sec24 PF04810.15 KFM57001.1 - 0.031 14.3 47.4 0.47 10.6 0.4 12.0 8 4 5 13 13 13 0 Sec23/Sec24 zinc finger K_oxygenase PF13434.6 KFM57001.1 - 0.038 13.1 0.6 14 4.7 0.0 4.0 3 2 1 5 5 5 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-FPG_IleRS PF06827.14 KFM57001.1 - 0.062 13.2 42.6 2.5 8.0 0.1 11.7 13 0 0 13 13 13 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 KFM57001.1 - 0.13 12.4 48.8 0.42 10.8 0.7 8.5 5 3 4 9 9 9 0 Zinc ribbon domain Zf_RING PF16744.5 KFM57001.1 - 0.42 10.7 67.5 0.57 10.3 0.7 12.4 2 2 8 11 11 11 0 KIAA1045 RING finger zf-MYST PF17772.1 KFM57001.1 - 5 6.8 67.5 0.85 9.3 0.3 12.2 5 3 8 13 13 13 0 MYST family zinc finger domain WD40 PF00400.32 KFM57002.1 - 1.2e-19 70.2 14.2 6.4e-07 30.0 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM57002.1 - 1.1e-13 51.2 0.0 0.084 13.2 0.0 5.8 2 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM57002.1 - 3.1e-05 24.0 0.4 0.19 11.6 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.15 KFM57002.1 - 0.0047 16.3 0.1 0.29 10.4 0.0 2.4 2 1 0 3 3 3 1 CPSF A subunit region PD40 PF07676.12 KFM57002.1 - 0.01 15.8 1.4 2.5 8.1 0.8 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFM57002.1 - 0.028 13.4 1.0 3.6 6.5 0.0 3.3 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KFM57002.1 - 0.15 11.7 0.0 24 4.7 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature HTH_Tnp_Tc3_2 PF01498.18 KFM57004.1 - 4e-19 68.6 5.4 9.7e-18 64.2 2.4 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57004.1 - 1.2e-16 60.8 0.0 7.3e-16 58.2 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM57004.1 - 3.1e-06 27.7 0.5 3.1e-06 27.7 0.5 1.9 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM57004.1 - 2.9e-05 23.9 0.7 0.00017 21.4 0.1 2.3 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM57004.1 - 8.5e-05 22.5 0.2 0.00099 19.0 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_29 PF13551.6 KFM57004.1 - 0.00013 21.9 0.1 0.00085 19.3 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KFM57004.1 - 0.00082 19.1 0.1 0.013 15.3 0.0 2.6 2 1 0 2 2 2 1 Homeodomain-like domain TrmB PF01978.19 KFM57004.1 - 0.00096 19.0 0.3 0.38 10.7 0.0 3.3 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 KFM57004.1 - 0.0024 18.0 0.6 0.091 12.9 0.0 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM57004.1 - 0.0036 17.3 0.7 0.9 9.7 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 KFM57004.1 - 0.0072 16.5 0.1 2.5 8.3 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 KFM57004.1 - 0.069 13.1 0.2 5.5 7.0 0.0 2.6 2 0 0 2 2 2 0 HTH domain GntR PF00392.21 KFM57004.1 - 0.095 12.4 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 KFM57004.1 - 0.18 12.0 0.0 3 8.1 0.0 2.2 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain SelP_N PF04592.14 KFM57005.1 - 1.5 8.2 6.1 3.6 6.9 6.1 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Lectin_C PF00059.21 KFM57008.1 - 0.0016 19.1 0.0 0.0068 17.1 0.0 1.9 2 0 0 2 2 2 1 Lectin C-type domain F5_F8_type_C PF00754.25 KFM57009.1 - 7e-10 39.1 0.0 1.7e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain fn3 PF00041.21 KFM57009.1 - 0.11 12.9 5.2 6.3 7.2 0.6 3.8 3 2 0 3 3 3 0 Fibronectin type III domain UL45 PF05473.12 KFM57009.1 - 0.17 11.5 0.2 0.35 10.5 0.2 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like TAF6_C PF07571.13 KFM57010.1 - 8.6e-08 32.4 0.0 2.9e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KFM57010.1 - 3e-07 30.5 0.0 3e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) NPC1_N PF16414.5 KFM57011.1 - 4.6e-54 183.6 7.2 5.3e-54 183.4 7.2 1.0 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Folate_rec PF03024.14 KFM57011.1 - 0.0025 17.7 7.2 0.0045 16.9 7.2 1.4 1 1 0 1 1 1 1 Folate receptor family TPT PF03151.16 KFM57012.1 - 0.014 14.8 0.8 0.016 14.5 0.8 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family TPT PF03151.16 KFM57013.1 - 0.0053 16.1 0.6 0.0056 16.1 0.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF751 PF05421.11 KFM57013.1 - 1.1 10.0 7.6 2.9 8.7 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF751) TPT PF03151.16 KFM57014.1 - 0.0016 17.9 0.9 0.0019 17.6 0.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family MtN3_slv PF03083.16 KFM57014.1 - 0.018 15.0 1.3 0.025 14.6 1.3 1.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange EamA PF00892.20 KFM57014.1 - 0.026 14.7 1.5 0.032 14.4 1.5 1.1 1 0 0 1 1 1 0 EamA-like transporter family p25-alpha PF05517.12 KFM57015.1 - 1.8e-44 151.6 8.7 2.2e-44 151.3 8.7 1.1 1 0 0 1 1 1 1 p25-alpha tRNA-synt_1b PF00579.25 KFM57015.1 - 0.025 13.9 1.5 0.033 13.5 1.5 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) RPN2_C PF18004.1 KFM57016.1 - 9.9e-50 168.6 33.5 4.8e-49 166.4 28.4 3.1 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KFM57016.1 - 3.8e-44 147.0 18.6 2.4e-09 37.2 0.1 8.0 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFM57016.1 - 3e-19 69.2 0.3 1.5e-14 54.1 0.0 4.1 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.22 KFM57016.1 - 1.4e-06 28.0 0.8 0.54 10.7 0.0 6.4 7 0 0 7 7 6 1 HEAT repeat HEAT_EZ PF13513.6 KFM57016.1 - 0.00068 20.1 0.7 0.2 12.2 0.1 4.1 3 1 2 5 5 5 2 HEAT-like repeat HEAT_PBS PF03130.16 KFM57016.1 - 0.0093 16.5 5.2 12 6.9 0.0 4.9 5 0 0 5 5 4 2 PBS lyase HEAT-like repeat Clathrin_H_link PF13838.6 KFM57016.1 - 0.011 15.6 0.1 0.032 14.1 0.1 1.8 1 0 0 1 1 1 0 Clathrin-H-link Zip PF02535.22 KFM57016.1 - 0.13 11.4 2.1 0.27 10.4 2.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 KFM57016.1 - 2.1 8.3 11.9 4.7 7.1 11.9 1.5 1 0 0 1 1 1 0 Protein Family FAM60A DUF262 PF03235.14 KFM57016.1 - 2.9 8.0 7.4 3.6 7.7 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF262 FAM76 PF16046.5 KFM57016.1 - 6.3 6.1 17.3 12 5.1 17.3 1.4 1 0 0 1 1 1 0 FAM76 protein DDHD PF02862.17 KFM57016.1 - 7.6 6.6 7.3 20 5.2 7.3 1.7 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.7 KFM57016.1 - 7.7 4.5 13.8 13 3.8 13.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CBM_14 PF01607.24 KFM57017.1 - 7e-10 38.9 6.4 1.4e-09 38.0 6.4 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Pkinase PF00069.25 KFM57018.1 - 2.3e-17 63.3 0.0 4.6e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57018.1 - 1.4e-08 34.3 0.0 4.2e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KFM57018.1 - 0.022 15.0 1.0 0.19 12.0 0.2 2.6 2 0 0 2 2 2 0 HEAT repeat DEAD PF00270.29 KFM57019.1 - 3e-40 137.8 0.1 5e-40 137.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM57019.1 - 2.5e-30 105.1 0.0 5.2e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM57019.1 - 1.1e-05 25.4 0.0 5.1e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit I-set PF07679.16 KFM57020.1 - 2.5e-35 120.4 0.0 1.9e-17 63.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain RhoGEF PF00621.20 KFM57020.1 - 2.4e-26 93.1 4.6 2.4e-26 93.1 4.6 1.5 2 0 0 2 2 2 1 RhoGEF domain Ig_3 PF13927.6 KFM57020.1 - 2.2e-21 76.2 0.0 2e-10 41.1 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM57020.1 - 5.5e-14 52.3 0.6 3.4e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM57020.1 - 1.7e-09 37.7 0.1 0.00015 21.9 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM57020.1 - 5.5e-06 26.5 1.1 0.037 14.2 0.1 3.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain PH PF00169.29 KFM57020.1 - 1.9e-05 25.1 0.1 6.7e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 PH domain C2-set_2 PF08205.12 KFM57020.1 - 0.00029 20.8 0.0 0.76 9.9 0.0 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain SH3_10 PF17902.1 KFM57020.1 - 0.00038 20.5 0.0 0.00096 19.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_1 PF00018.28 KFM57020.1 - 0.017 14.7 0.0 0.052 13.2 0.0 1.9 1 0 0 1 1 1 0 SH3 domain PH_10 PF15411.6 KFM57020.1 - 0.034 14.4 0.2 0.32 11.3 0.2 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain SH3_9 PF14604.6 KFM57020.1 - 0.095 12.6 0.8 0.21 11.4 0.1 2.1 2 0 0 2 2 1 0 Variant SH3 domain Receptor_2B4 PF11465.8 KFM57020.1 - 0.099 12.9 0.0 3.2 8.0 0.0 2.8 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 Phage_F PF02305.17 KFM57020.1 - 0.12 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Capsid protein (F protein) DUF4795 PF16043.5 KFM57020.1 - 2 8.0 9.8 4.4 6.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) PWWP PF00855.17 KFM57022.1 - 6.6e-15 55.3 0.4 6.6e-15 55.3 0.4 3.4 2 1 0 2 2 2 1 PWWP domain EF-hand_7 PF13499.6 KFM57023.1 - 2.9e-06 27.6 4.2 9.3e-06 26.0 4.2 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM57023.1 - 7.7e-05 22.0 2.6 0.0096 15.4 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM57023.1 - 0.0012 18.6 2.9 0.035 14.0 0.3 2.8 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KFM57023.1 - 0.0028 17.5 1.1 0.0074 16.1 0.0 2.2 3 0 0 3 3 3 1 EF-hand domain pair Myb_DNA-bind_5 PF13873.6 KFM57025.1 - 4e-16 58.9 1.5 5.4e-16 58.4 1.5 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFM57025.1 - 2e-08 34.5 0.9 2.8e-08 34.0 0.9 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM57025.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 KFM57025.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1664 PF07889.12 KFM57025.1 - 0.039 14.0 0.3 0.06 13.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CNP1 PF08750.11 KFM57025.1 - 0.054 13.4 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 CNP1-like family Hormone_1 PF00103.20 KFM57025.1 - 0.13 12.0 0.2 0.18 11.5 0.2 1.1 1 0 0 1 1 1 0 Somatotropin hormone family DUF3020 PF11223.8 KFM57025.1 - 7.8 7.1 8.8 0.92 10.1 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) zf-H2C2_2 PF13465.6 KFM57026.1 - 6.6e-84 272.9 106.1 6.4e-09 35.8 3.4 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57026.1 - 1.8e-58 191.8 121.3 1.1e-06 28.7 0.9 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57026.1 - 1.4e-37 125.1 113.6 0.00054 20.6 1.5 12.2 12 0 0 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM57026.1 - 9.7e-29 98.9 114.8 0.0013 19.1 2.6 12.2 12 0 0 12 12 12 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM57026.1 - 2.2e-20 72.4 96.6 0.0058 16.9 0.7 12.2 12 0 0 12 12 12 11 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM57026.1 - 2.4e-20 72.1 110.4 0.02 14.9 2.6 12.7 12 1 0 12 12 12 11 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM57026.1 - 9.9e-18 63.6 60.0 0.0043 16.8 1.6 12.2 12 0 0 12 12 12 7 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 KFM57026.1 - 2.5e-09 36.9 62.0 0.15 11.9 0.2 11.9 2 1 10 12 12 12 6 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFM57026.1 - 3.3e-08 33.1 81.5 0.007 16.1 1.2 11.8 12 1 0 12 12 11 8 zinc-finger C2H2-type GAGA PF09237.11 KFM57026.1 - 8.8e-08 31.8 27.1 0.42 10.5 0.1 9.4 1 1 11 12 12 12 4 GAGA factor BolA PF01722.18 KFM57026.1 - 4.6e-06 26.8 27.6 0.016 15.5 0.1 7.5 2 2 7 10 10 10 2 BolA-like protein Tox-HNH-HHH PF15637.6 KFM57026.1 - 1.7e-05 24.9 14.4 0.57 10.4 0.4 5.2 1 1 7 8 8 8 3 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF3396 PF11876.8 KFM57026.1 - 8.4e-05 22.1 0.0 5.4 6.4 0.0 5.0 1 1 4 6 6 6 1 Protein of unknown function (DUF3396) zf-C2HC_2 PF13913.6 KFM57026.1 - 0.00063 19.6 62.8 1.1 9.3 0.3 12.3 12 0 0 12 12 12 4 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM57026.1 - 0.00088 19.3 62.6 1.9 8.6 1.9 5.7 1 1 4 5 5 5 3 Putative ribonucleoprotein zinc-finger pf C4 type Complex1_49kDa PF00346.19 KFM57026.1 - 0.064 12.3 5.1 2.6 7.1 0.2 2.7 1 1 2 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF2256 PF10013.9 KFM57026.1 - 0.076 13.1 55.9 2.4 8.4 0.2 11.8 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4825 PF16107.5 KFM57026.1 - 0.17 12.0 0.5 14 5.9 0.0 3.7 3 2 2 5 5 5 0 Domain of unknown function (DUF4825) RcsD_ABL PF16359.5 KFM57026.1 - 0.39 10.9 1.1 35 4.6 0.0 3.2 3 0 0 3 3 3 0 RcsD-ABL domain zf-C2H2_2 PF12756.7 KFM57026.1 - 1.8 9.0 102.6 3.1 8.2 2.5 11.9 1 1 11 12 12 12 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFM57026.1 - 3.6 7.5 80.5 4.5 7.3 2.6 10.4 4 4 4 8 8 8 0 Phorbol esters/diacylglycerol binding domain (C1 domain) VirE1 PF12189.8 KFM57026.1 - 9.6 6.4 7.6 31 4.8 0.1 4.5 4 1 2 6 6 6 0 Single-strand DNA-binding protein DDE_3 PF13358.6 KFM57028.1 - 5e-16 58.8 0.1 5.9e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57028.1 - 7.6e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57028.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57028.1 - 0.024 14.4 0.1 1.1 9.1 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_29 PF13551.6 KFM57028.1 - 0.082 12.9 2.6 0.088 12.8 0.3 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Pkinase_Tyr PF07714.17 KFM57032.1 - 8.5e-41 139.9 0.0 2.1e-35 122.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM57032.1 - 5.3e-40 137.4 0.0 1e-38 133.3 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 KFM57032.1 - 9.6e-24 82.9 25.1 3e-10 39.7 1.7 5.4 5 0 0 5 5 5 4 Leucine rich repeat COR PF16095.5 KFM57032.1 - 1.1e-22 80.9 0.0 7.4e-22 78.1 0.0 2.3 2 1 0 2 2 2 1 C-terminal of Roc, COR, domain LRR_4 PF12799.7 KFM57032.1 - 1.1e-22 79.7 22.1 4.3e-06 27.0 0.4 7.1 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) Roc PF08477.13 KFM57032.1 - 2e-18 66.8 0.2 5.6e-15 55.6 0.0 2.6 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 KFM57032.1 - 1.7e-14 54.2 3.0 0.0003 21.3 0.2 5.0 4 1 1 5 5 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM57032.1 - 3.6e-10 39.9 0.0 0.0017 18.6 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ras PF00071.22 KFM57032.1 - 5.8e-09 35.7 0.0 4.1e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 Ras family Ank_3 PF13606.6 KFM57032.1 - 7.4e-09 35.2 0.1 0.0024 18.2 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFM57032.1 - 8.8e-08 32.3 0.1 8e-05 22.9 0.1 3.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KFM57032.1 - 2.2e-05 24.9 0.1 0.00051 20.6 0.0 3.2 3 1 0 3 3 2 1 Ankyrin repeats (many copies) Arf PF00025.21 KFM57032.1 - 0.0095 15.4 0.2 2.1 7.8 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family LRR_1 PF00560.33 KFM57032.1 - 0.088 13.4 24.0 38 5.4 0.0 9.5 9 1 0 9 9 9 0 Leucine Rich Repeat Kdo PF06293.14 KFM57032.1 - 0.14 11.5 0.1 0.45 9.8 0.1 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Macoilin PF09726.9 KFM57033.1 - 3e-253 842.4 12.7 3.3e-253 842.2 12.7 1.0 1 0 0 1 1 1 1 Macoilin family PKcGMP_CC PF16808.5 KFM57033.1 - 0.022 14.6 8.0 0.089 12.7 0.8 3.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GAS PF13851.6 KFM57033.1 - 0.18 11.1 43.5 0.011 15.1 28.1 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KFM57033.1 - 0.42 10.7 21.8 0.4 10.7 2.9 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF4763 PF15960.5 KFM57033.1 - 0.58 9.4 29.4 0.047 13.0 12.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) Lzipper-MIP1 PF14389.6 KFM57033.1 - 1.4 9.3 31.4 6.3 7.2 8.9 5.0 1 1 3 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 KASH_CCD PF14662.6 KFM57033.1 - 1.9 8.3 38.7 0.85 9.4 17.6 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4806 PF16064.5 KFM57033.1 - 6.2 7.2 9.1 1.2 9.5 1.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4806) adh_short PF00106.25 KFM57034.1 - 1.7e-07 30.9 0.4 1.8e-07 30.8 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM57034.1 - 0.0012 18.5 0.2 0.0013 18.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HTH_39 PF14090.6 KFM57035.1 - 0.072 12.9 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain LINES_N PF14694.6 KFM57036.1 - 9.9e-07 28.5 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Lines N-terminus DUF4777 PF16007.5 KFM57036.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) JSRP PF15312.6 KFM57038.1 - 0.083 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein BESS PF02944.20 KFM57039.1 - 2.8e-08 33.4 1.5 5.6e-08 32.5 1.5 1.6 1 0 0 1 1 1 1 BESS motif Spt20 PF12090.8 KFM57041.1 - 2.9e-17 63.1 3.0 3.6e-08 33.3 1.0 2.5 1 1 1 2 2 2 2 Spt20 family Tnp_zf-ribbon_2 PF13842.6 KFM57043.1 - 0.00053 20.7 2.5 0.0014 19.4 2.5 1.7 1 1 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon Ribosomal_L44 PF00935.19 KFM57043.1 - 0.58 10.7 6.1 0.12 12.8 3.1 1.4 1 1 1 2 2 2 0 Ribosomal protein L44 LRR_8 PF13855.6 KFM57044.1 - 1e-05 25.2 0.0 3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat TMEM192 PF14802.6 KFM57044.1 - 0.017 14.2 1.4 0.024 13.7 0.3 1.8 2 0 0 2 2 2 0 TMEM192 family DUF4492 PF14899.6 KFM57044.1 - 0.021 14.7 0.2 0.048 13.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Claudin_2 PF13903.6 KFM57044.1 - 0.036 13.8 1.2 0.059 13.1 0.1 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF167 PF02594.16 KFM57045.1 - 1.4e-24 86.0 0.5 1.4e-24 86.0 0.5 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YggU family COG1872 DDE_3 PF13358.6 KFM57046.1 - 5.6e-16 58.6 0.1 6.4e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57046.1 - 7.1e-16 58.2 6.5 1.5e-15 57.1 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57046.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM57046.1 - 0.056 13.5 0.4 0.056 13.5 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix zf-H2C2_2 PF13465.6 KFM57048.1 - 7.8e-42 139.9 58.6 7.9e-08 32.4 3.7 8.0 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57048.1 - 2.3e-29 100.2 61.3 0.0001 22.6 1.5 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57048.1 - 1e-22 78.8 56.5 0.00094 19.8 1.4 7.2 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM57048.1 - 1.3e-10 41.0 45.6 0.00014 21.7 2.6 7.4 7 2 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM57048.1 - 2.9e-10 40.2 51.6 0.0079 16.6 1.2 7.5 7 1 0 7 7 7 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM57048.1 - 1.9e-05 24.3 38.9 0.17 11.6 0.4 7.5 7 0 0 7 7 7 4 C2H2-type zinc-finger domain BolA PF01722.18 KFM57048.1 - 0.00045 20.4 6.9 0.21 11.9 0.5 3.9 2 1 1 3 3 3 1 BolA-like protein GAGA PF09237.11 KFM57048.1 - 0.0023 17.7 11.5 0.78 9.6 0.2 5.0 2 1 4 6 6 6 2 GAGA factor zf-C2H2_8 PF15909.5 KFM57048.1 - 0.087 13.1 29.6 1.4 9.3 9.3 3.8 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFM57048.1 - 0.14 12.5 0.4 0.14 12.5 0.4 7.0 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KFM57048.1 - 0.52 11.0 25.5 7.6 7.2 1.7 5.5 2 2 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-MYST PF17772.1 KFM57048.1 - 1.1 8.9 39.1 1.5 8.4 0.2 6.8 1 1 6 7 7 7 0 MYST family zinc finger domain LEDGF PF11467.8 KFM57050.1 - 1.3e-09 37.7 0.4 1.3e-09 37.7 0.4 4.2 3 1 1 4 4 4 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.17 KFM57050.1 - 4.4e-09 36.6 0.2 4.4e-09 36.6 0.2 4.5 3 1 0 4 4 4 1 PWWP domain RVT_1 PF00078.27 KFM57051.1 - 0.011 15.2 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_2 PF13639.6 KFM57053.1 - 1.1e-09 38.5 8.1 1.1e-09 38.5 8.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KFM57053.1 - 1.8e-06 28.1 8.7 1.8e-06 28.1 8.7 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFM57053.1 - 7.9e-06 25.6 8.6 7.9e-06 25.6 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM57053.1 - 8.4e-05 22.4 10.7 0.00011 22.0 8.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM57053.1 - 0.00011 21.9 3.3 0.00025 20.7 3.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KFM57053.1 - 0.00011 22.1 5.2 0.00011 22.1 5.2 1.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM57053.1 - 0.00044 20.1 6.4 0.00044 20.1 6.4 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFM57053.1 - 0.0008 19.4 2.9 0.0013 18.8 2.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KFM57053.1 - 0.0012 18.8 3.7 0.0012 18.8 3.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KFM57053.1 - 0.002 17.7 4.9 0.0035 16.9 4.9 1.5 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KFM57053.1 - 0.01 15.7 5.4 0.01 15.7 5.4 1.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zinc_ribbon_16 PF17034.5 KFM57053.1 - 0.01 16.0 3.3 0.01 16.0 3.3 1.4 1 1 0 1 1 1 0 Zinc-ribbon like family zf-RING_9 PF13901.6 KFM57053.1 - 0.038 14.0 7.0 0.038 14.0 7.0 1.8 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon FANCL_C PF11793.8 KFM57053.1 - 0.16 12.2 5.8 3.6 7.8 5.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KFM57053.1 - 0.21 11.7 7.1 0.65 10.1 7.1 1.9 1 1 0 1 1 1 0 Zinc-finger zf-Nse PF11789.8 KFM57053.1 - 0.27 11.1 5.6 1.3 8.9 5.6 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 KFM57053.1 - 2.4 8.5 12.2 0.96 9.8 7.1 2.1 2 0 0 2 2 2 0 RING-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57054.1 - 2.7e-19 69.2 3.6 6.4e-19 68.0 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57054.1 - 5.4e-16 58.7 0.0 2.7e-15 56.4 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM57054.1 - 2.7e-07 30.6 0.4 0.00016 21.7 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM57054.1 - 3.3e-07 30.3 2.6 8.4e-05 22.6 0.2 3.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM57054.1 - 4e-07 30.5 2.0 4e-07 30.5 2.0 2.3 3 0 0 3 3 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM57054.1 - 3.2e-06 27.0 0.7 4.4e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KFM57054.1 - 7.1e-06 25.7 5.5 2.8e-05 23.8 0.0 3.2 3 1 0 3 3 3 1 Homeodomain-like domain MarR_2 PF12802.7 KFM57054.1 - 0.00015 21.6 0.7 0.0019 18.0 0.0 2.5 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM57054.1 - 0.0014 18.6 0.3 0.018 15.0 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM57054.1 - 0.025 14.2 0.1 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM57054.1 - 0.051 13.6 0.1 2.2 8.4 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM57054.1 - 0.098 12.9 0.1 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 KFM57054.1 - 0.33 10.8 3.8 1.6 8.6 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM57054.1 - 1.3 8.5 3.6 7.8 6.0 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 PBP PF01161.20 KFM57055.1 - 1.1e-09 38.7 0.0 5.5e-09 36.4 0.0 1.9 1 1 0 2 2 2 1 Phosphatidylethanolamine-binding protein APCDDC PF14921.6 KFM57056.1 - 5e-35 121.1 0.2 2.6e-20 72.9 0.0 2.5 2 1 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 APCDDC PF14921.6 KFM57057.1 - 3e-32 111.9 0.1 3.7e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 Adenomatosis polyposis coli down-regulated 1 Transposase_1 PF01359.18 KFM57058.1 - 1.5e-12 47.2 0.3 4.2e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM57058.1 - 1.6e-08 34.5 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_50 PF18024.1 KFM57058.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain WH2 PF02205.20 KFM57059.1 - 0.0023 17.7 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 WH2 motif Na_K-ATPase PF00287.18 KFM57059.1 - 0.22 10.6 2.8 0.33 10.1 2.8 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Tyosinase_C PF18132.1 KFM57060.1 - 0.035 14.8 0.3 0.21 12.3 0.0 2.2 2 0 0 2 2 2 0 Tyosinase C-terminal domain Caskin1-CID PF16600.5 KFM57060.1 - 0.75 10.4 12.5 2.3 8.8 12.5 1.9 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain HTH_Tnp_Tc3_2 PF01498.18 KFM57061.1 - 2.3e-17 63.0 0.5 5.3e-17 61.8 0.5 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57061.1 - 1.9e-08 34.2 0.0 3.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57062.1 - 2.2e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57062.1 - 9.7e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57063.1 - 6.6e-05 22.7 0.0 8.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DRIM PF07539.12 KFM57063.1 - 0.13 10.6 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis TraE PF05309.11 KFM57065.1 - 0.45 9.9 4.7 2.5 7.4 1.0 2.1 2 0 0 2 2 2 0 TraE protein Peptidase_M1 PF01433.20 KFM57066.1 - 2.5e-81 272.4 1.7 5e-81 271.4 1.7 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFM57066.1 - 2.9e-48 164.5 1.1 5.9e-48 163.5 1.1 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 KFM57066.1 - 4.7e-28 98.7 0.5 7.9e-28 97.9 0.5 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Neural_ProG_Cyt PF06567.11 KFM57066.1 - 0.085 13.1 0.0 19 5.5 0.0 2.4 2 0 0 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain DUF1570 PF07607.11 KFM57066.1 - 0.13 12.6 0.4 0.5 10.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) ERAP1_C PF11838.8 KFM57067.1 - 0.0054 16.3 0.0 0.0061 16.1 0.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain MG1 PF17790.1 KFM57068.1 - 0.00034 21.0 0.0 0.00044 20.6 0.0 1.1 1 0 0 1 1 1 1 Macroglobulin domain MG1 A2M_BRD PF07703.14 KFM57069.1 - 3.5e-18 66.3 0.0 3.7e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFM57070.1 - 2.5e-26 91.3 0.0 5.4e-26 90.3 0.0 1.5 2 0 0 2 2 2 1 Alpha-2-macroglobulin family SVA PF05326.11 KFM57070.1 - 3.1e-05 24.0 0.0 9.2e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Seminal vesicle autoantigen (SVA) TED_complement PF07678.14 KFM57071.1 - 1.6e-86 290.2 0.1 2.2e-86 289.8 0.1 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 KFM57071.1 - 1.2e-24 86.8 1.5 2.6e-24 85.7 1.5 1.6 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain EAP30 PF04157.16 KFM57071.1 - 0.14 11.5 0.0 0.51 9.6 0.0 2.0 1 1 0 1 1 1 0 EAP30/Vps36 family THAP PF05485.12 KFM57074.1 - 3.4e-09 37.5 8.7 6e-09 36.7 8.7 1.4 1 0 0 1 1 1 1 THAP domain Pkinase PF00069.25 KFM57076.1 - 3.7e-31 108.4 0.0 4.9e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57076.1 - 3.7e-17 62.5 0.0 5.4e-17 61.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM57076.1 - 0.00035 20.0 0.0 0.00051 19.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM57076.1 - 0.047 13.0 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFM57077.1 - 6.9e-11 42.0 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57077.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_19 PF18015.1 KFM57077.1 - 0.024 14.9 0.1 0.062 13.5 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gag_p12 PF01141.18 KFM57078.1 - 0.04 14.2 0.1 0.053 13.9 0.1 1.1 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 HTH_Tnp_Tc3_2 PF01498.18 KFM57079.1 - 2.7e-16 59.6 2.2 5e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57079.1 - 4.5e-14 52.4 0.0 7.3e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.18 KFM57080.1 - 2.1e-22 78.7 0.2 2.1e-22 78.7 0.2 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_50 PF18024.1 KFM57080.1 - 1.3e-05 24.7 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM57080.1 - 0.00026 21.2 0.0 0.00049 20.3 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_11 PF08279.12 KFM57080.1 - 0.001 18.9 0.1 0.0023 17.8 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_32 PF13565.6 KFM57080.1 - 0.0047 17.5 0.5 0.014 16.0 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_10 PF04967.12 KFM57080.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain M60-like_N PF17291.2 KFM57080.1 - 0.025 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases GerE PF00196.19 KFM57080.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 KFM57080.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 KFM57080.1 - 0.099 12.5 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 KFM57080.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM57080.1 - 0.17 11.8 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 Tc3 transposase UCMA PF17085.5 KFM57082.1 - 0.00099 19.1 6.5 0.026 14.5 0.0 2.2 2 0 0 2 2 2 2 Unique cartilage matrix associated protein TERB2 PF15101.6 KFM57082.1 - 0.015 15.3 1.5 0.024 14.7 1.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Fe-S_biosyn PF01521.20 KFM57083.1 - 2.7e-19 69.4 0.0 3.1e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.7 KFM57083.1 - 0.00069 19.7 0.0 0.00095 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3853) A_deaminase PF00962.22 KFM57086.1 - 2.2e-11 43.6 0.1 2.2e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Toprim PF01751.22 KFM57086.1 - 0.017 15.3 0.1 0.022 15.0 0.1 1.2 1 0 0 1 1 1 0 Toprim domain A_deaminase PF00962.22 KFM57087.1 - 8.9e-63 212.6 0.0 1e-62 212.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KFM57087.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family Mga PF05043.13 KFM57088.1 - 0.027 15.1 0.4 0.032 14.8 0.4 1.1 1 0 0 1 1 1 0 Mga helix-turn-helix domain zf-H2C2_2 PF13465.6 KFM57089.1 - 6.1e-67 219.3 72.7 3.7e-11 42.9 0.4 10.0 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57089.1 - 2.3e-47 156.9 81.6 1.2e-06 28.7 2.3 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57089.1 - 6.6e-33 110.5 73.9 4.9e-05 23.8 0.5 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM57089.1 - 4.8e-14 51.8 69.3 6.3e-05 22.6 5.9 10.5 10 1 0 10 10 10 5 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM57089.1 - 1.3e-12 47.4 66.9 0.011 15.7 0.8 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM57089.1 - 4.6e-08 33.1 48.4 0.15 12.3 0.1 9.2 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM57089.1 - 1.6e-07 31.5 68.5 0.023 15.1 0.5 9.4 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFM57089.1 - 4.9e-05 23.6 42.6 0.15 12.4 3.8 5.1 1 1 4 5 5 5 4 C2H2-type zinc ribbon GAGA PF09237.11 KFM57089.1 - 0.0025 17.6 18.0 5.3 6.9 3.5 6.0 2 2 3 6 6 6 2 GAGA factor zf-C2H2_2 PF12756.7 KFM57089.1 - 0.0026 18.1 54.9 3.7 7.9 0.3 7.9 1 1 7 8 8 8 3 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFM57089.1 - 0.013 15.2 0.4 0.013 15.2 0.4 8.4 9 0 0 9 9 9 0 zinc-finger C2H2-type BolA PF01722.18 KFM57089.1 - 0.016 15.5 10.4 20 5.6 0.1 5.8 2 2 4 6 6 6 0 BolA-like protein TRAF6_Z2 PF18048.1 KFM57089.1 - 0.03 14.4 3.4 0.03 14.4 3.4 6.7 9 0 0 9 9 9 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_15 PF17032.5 KFM57089.1 - 0.14 12.9 40.6 2.1 9.2 5.1 4.7 1 1 5 6 6 6 0 zinc-ribbon family zf-C2HE PF16278.5 KFM57089.1 - 0.16 12.4 55.7 0.27 11.7 0.4 7.6 2 2 6 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KFM57089.1 - 0.45 10.7 40.6 1.7 8.8 1.4 6.8 4 2 3 7 7 7 0 Zinc ribbon domain Protamine_3 PF08188.11 KFM57089.1 - 0.52 10.6 4.7 1.1 9.6 0.0 3.1 3 1 0 3 3 3 0 Spermatozal protamine family zf-RING_11 PF17123.5 KFM57089.1 - 0.68 9.7 18.3 1.7 8.5 0.3 5.2 5 0 0 5 5 5 0 RING-like zinc finger zf-C2H2_9 PF16293.5 KFM57089.1 - 3.3 7.6 34.0 1.9 8.4 0.1 7.8 4 3 5 9 9 9 0 C2H2 type zinc-finger (1 copy) C1_4 PF07975.12 KFM57089.1 - 3.6 7.9 50.9 1.5 9.1 4.1 6.8 1 1 5 7 7 7 0 TFIIH C1-like domain Scramblase PF03803.15 KFM57089.1 - 5.4 6.2 9.2 12 5.1 0.9 3.1 1 1 4 5 5 5 0 Scramblase PRP21_like_P PF12230.8 KFM57089.1 - 8 6.3 8.1 2.3 8.1 0.1 3.1 2 1 2 4 4 4 0 Pre-mRNA splicing factor PRP21 like protein zf-H2C2_2 PF13465.6 KFM57090.1 - 8.4e-99 320.0 112.9 2.5e-08 34.0 0.3 16.0 16 0 0 16 16 16 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57090.1 - 1e-65 214.7 135.4 1.7e-06 28.1 0.7 15.1 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57090.1 - 1.1e-49 162.7 124.8 0.00032 21.3 0.6 15.1 15 0 0 15 15 15 15 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM57090.1 - 8.1e-26 89.5 112.8 0.00046 20.1 0.4 15.3 15 0 0 15 15 15 13 C2H2-type zinc finger zf-met PF12874.7 KFM57090.1 - 3e-19 68.7 116.4 0.0013 19.1 1.0 15.3 15 1 0 15 15 15 12 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM57090.1 - 2.3e-14 52.8 107.3 0.0041 16.8 5.4 16.1 16 0 0 16 16 16 9 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM57090.1 - 5.1e-12 45.7 86.9 0.00098 19.3 0.2 14.5 14 2 1 15 15 14 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM57090.1 - 0.00027 21.1 17.0 6.8 7.0 0.6 8.5 3 2 6 10 10 10 1 BolA-like protein Baculo_IE-1 PF05290.11 KFM57090.1 - 0.032 14.2 48.8 9.8 6.1 2.3 9.9 1 1 8 9 9 9 0 Baculovirus immediate-early protein (IE-0) zf-LYAR PF08790.11 KFM57090.1 - 0.09 12.7 0.6 0.09 12.7 0.6 10.5 12 0 0 12 12 11 0 LYAR-type C2HC zinc finger GAGA PF09237.11 KFM57090.1 - 0.31 10.9 20.0 2.7 7.8 0.0 6.9 5 3 2 8 8 8 0 GAGA factor Elongin_A PF06881.11 KFM57091.1 - 2.3e-18 66.6 1.9 2.3e-18 66.6 1.9 2.7 3 0 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 KFM57091.1 - 0.001 19.1 0.0 0.0034 17.4 0.0 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DnaB_2 PF07261.11 KFM57091.1 - 0.11 12.2 0.8 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Replication initiation and membrane attachment Proteasome PF00227.26 KFM57092.1 - 4.8e-42 143.6 0.0 5.4e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit KA1 PF02149.19 KFM57093.1 - 1.9e-07 30.7 0.0 4.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Pkinase PF00069.25 KFM57096.1 - 1.2e-21 77.3 0.0 1.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57096.1 - 2.4e-07 30.3 0.0 3.4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM57096.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KFM57097.1 - 2.1e-24 86.3 1.9 2.3e-24 86.2 1.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57097.1 - 3e-17 62.8 1.4 3.2e-17 62.7 1.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M13 PF01431.21 KFM57098.1 - 1.9e-15 57.1 0.1 5.8e-12 45.7 0.0 2.0 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.21 KFM57099.1 - 1.7e-29 102.9 0.0 1.8e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM57100.1 - 3.1e-21 76.5 1.6 3.9e-21 76.2 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M13 NAP PF00956.18 KFM57101.1 - 4.5e-99 331.0 7.4 4.5e-99 331.0 7.4 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Drc1-Sld2 PF11719.8 KFM57101.1 - 1.3 8.5 12.2 0.13 11.8 7.0 1.8 2 0 0 2 2 2 0 DNA replication and checkpoint protein RNA_pol_3_Rpc31 PF11705.8 KFM57101.1 - 2.8 8.1 23.6 0.055 13.7 14.3 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Sporozoite_P67 PF05642.11 KFM57101.1 - 2.9 5.9 7.2 5.1 5.0 7.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FRQ PF09421.10 KFM57101.1 - 4.5 5.2 10.9 7.8 4.4 10.9 1.3 1 0 0 1 1 1 0 Frequency clock protein KH_1 PF00013.29 KFM57102.1 - 1.9e-07 30.8 0.0 4.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 KH domain COesterase PF00135.28 KFM57104.1 - 5e-142 474.4 0.0 5.7e-142 474.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM57104.1 - 5.3e-08 33.0 0.1 3e-07 30.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2 PF00096.26 KFM57105.1 - 2.1e-33 112.9 50.8 3.8e-05 23.9 1.1 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM57105.1 - 1.2e-32 110.9 33.1 3.3e-09 36.7 0.6 7.9 7 2 0 7 7 7 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM57105.1 - 3.9e-24 83.2 50.0 0.00024 21.7 0.4 7.8 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM57105.1 - 2.8e-14 52.7 40.2 0.00016 21.6 1.0 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM57105.1 - 7.9e-10 38.8 35.9 0.0024 18.1 0.2 7.6 8 0 0 8 8 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM57105.1 - 1.2e-09 38.2 39.9 0.019 15.3 0.4 7.8 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM57105.1 - 8.9e-09 35.0 33.8 0.0011 18.6 0.1 6.1 6 0 0 6 6 6 4 zinc-finger C2H2-type zf-Di19 PF05605.12 KFM57105.1 - 7.7e-05 22.9 37.7 0.013 15.8 1.2 6.4 4 1 3 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFM57105.1 - 0.0013 18.6 21.6 0.0051 16.7 0.1 5.9 6 0 0 6 6 6 2 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM57105.1 - 0.03 14.2 0.9 0.03 14.2 0.9 6.2 5 1 2 7 7 7 0 C2H2 type zinc-finger (1 copy) zf-CHCC PF10276.9 KFM57105.1 - 0.085 12.9 0.3 0.085 12.9 0.3 3.9 4 0 0 4 4 4 0 Zinc-finger domain zf-MYST PF17772.1 KFM57105.1 - 0.14 11.8 12.9 4.3 7.0 0.0 4.6 5 0 0 5 5 5 0 MYST family zinc finger domain Rad50_zn_hook PF04423.14 KFM57105.1 - 0.27 11.1 3.1 26 4.7 0.2 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf_UBZ PF18439.1 KFM57105.1 - 0.71 9.5 29.4 1.7 8.3 0.9 6.7 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 KFM57105.1 - 5.3 7.4 19.0 5.8 7.3 0.6 5.8 6 0 0 6 6 6 0 zinc-ribbon zf-C2H2_2 PF12756.7 KFM57105.1 - 8 6.9 53.6 0.56 10.6 5.7 7.6 3 1 4 7 7 6 0 C2H2 type zinc-finger (2 copies) Synaptobrevin PF00957.21 KFM57106.1 - 2.3e-15 56.1 1.1 6.3e-15 54.7 0.4 1.8 1 1 1 2 2 2 2 Synaptobrevin R3H PF01424.22 KFM57107.1 - 1e-14 54.3 0.6 3.5e-14 52.5 0.1 2.2 2 0 0 2 2 2 1 R3H domain DUF2258 PF10015.9 KFM57108.1 - 0.033 14.3 0.1 0.067 13.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) HisKA PF00512.25 KFM57108.1 - 0.15 12.1 0.2 0.38 10.8 0.2 1.6 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain RFX_DNA_binding PF02257.15 KFM57109.1 - 4.2e-34 117.0 0.2 1.6e-33 115.2 0.1 2.0 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFM57109.1 - 0.067 13.7 0.2 0.28 11.7 0.0 2.0 3 0 0 3 3 3 0 Poxvirus D5 protein-like NTP_transf_3 PF12804.7 KFM57109.1 - 0.13 12.6 0.2 0.24 11.8 0.2 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain Homeodomain PF00046.29 KFM57110.1 - 1e-07 31.7 0.5 2.8e-07 30.3 0.5 1.8 1 0 0 1 1 1 1 Homeodomain DUF4290 PF14123.6 KFM57110.1 - 0.039 13.5 0.2 0.063 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) FTZ PF03867.14 KFM57110.1 - 0.091 12.3 0.2 0.091 12.3 0.2 1.6 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region NAD_binding_2 PF03446.15 KFM57112.1 - 9.8e-50 168.8 0.2 2.4e-49 167.6 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFM57112.1 - 8.3e-32 110.0 0.1 2.6e-31 108.4 0.0 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFM57112.1 - 2.4e-08 34.4 0.0 7e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KFM57112.1 - 1.8e-07 30.7 0.0 3.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KFM57112.1 - 0.0015 18.4 0.1 0.0031 17.4 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KFM57112.1 - 0.0095 15.6 0.0 1.6 8.2 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase ApbA PF02558.16 KFM57112.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 KFM57112.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KFM57112.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KFM57112.1 - 0.1 12.2 0.1 0.65 9.5 0.0 2.0 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 KFM57112.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4149 PF13664.6 KFM57113.1 - 0.018 15.3 1.5 0.037 14.3 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) HTH_Tnp_Tc3_2 PF01498.18 KFM57114.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57114.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57114.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57114.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57114.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57115.1 - 2.4e-16 59.7 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57115.1 - 2.5e-14 53.3 0.0 1.7e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57116.1 - 8.4e-16 58.0 6.5 1.5e-15 57.2 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57116.1 - 1.7e-15 57.0 0.1 2.1e-14 53.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM57116.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57116.1 - 0.029 14.2 0.1 1.2 9.0 0.1 3.1 3 0 0 3 3 3 0 Homeodomain-like domain Imm64 PF15600.6 KFM57117.1 - 0.0074 16.0 0.2 0.0086 15.8 0.2 1.1 1 0 0 1 1 1 1 Immunity protein 64 DUF2482 PF10655.9 KFM57117.1 - 0.034 14.6 0.1 0.077 13.5 0.1 1.5 1 1 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) zf-H2C2_2 PF13465.6 KFM57118.1 - 9.7e-07 28.9 17.7 1.6e-06 28.3 5.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57118.1 - 1.7e-06 28.2 18.0 0.00096 19.5 5.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57118.1 - 2.7e-06 27.8 16.9 0.006 17.3 5.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM57118.1 - 0.0068 16.7 10.6 0.012 15.9 1.7 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFM57118.1 - 0.026 14.8 4.2 0.031 14.6 4.2 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-MYST PF17772.1 KFM57118.1 - 0.033 13.8 3.6 0.67 9.6 0.9 2.2 2 0 0 2 2 2 0 MYST family zinc finger domain DUF2180 PF09947.9 KFM57118.1 - 0.13 12.3 1.1 0.23 11.5 1.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) zf-Di19 PF05605.12 KFM57118.1 - 0.33 11.3 5.5 0.51 10.7 5.5 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KFM57118.1 - 3.5 7.4 7.7 2.1 8.1 1.5 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 KFM57119.1 - 3e-11 43.1 18.0 7.2e-06 26.2 5.3 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM57119.1 - 3e-09 36.9 18.1 6.3e-09 35.9 4.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM57119.1 - 4.5e-08 33.3 16.4 0.00034 21.2 4.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM57119.1 - 5.1e-06 26.6 13.8 0.0078 16.5 3.3 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM57119.1 - 4.9e-05 23.6 12.0 0.01 16.2 1.7 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM57119.1 - 0.0015 18.8 5.8 0.0021 18.3 5.8 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFM57119.1 - 0.08 13.2 0.9 0.18 12.1 0.3 1.8 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_2 PF12756.7 KFM57119.1 - 0.11 12.9 7.2 0.68 10.3 0.7 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 KFM57119.1 - 0.12 12.7 6.1 0.13 12.6 6.1 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon FYVE PF01363.21 KFM57119.1 - 0.12 12.5 7.2 0.16 12.2 7.2 1.1 1 0 0 1 1 1 0 FYVE zinc finger zf-MYST PF17772.1 KFM57119.1 - 0.14 11.8 4.4 1.3 8.7 0.2 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain Actin_micro PF17003.5 KFM57119.1 - 0.85 8.7 8.8 0.34 10.1 1.3 2.0 1 1 1 2 2 2 0 Putative actin-like family DUF629 PF04780.12 KFM57119.1 - 8.4 4.8 10.7 1.5e+02 0.6 10.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.6 KFM57120.1 - 1.2e-11 44.5 18.4 1.2e-10 41.3 3.9 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM57120.1 - 1.7e-07 31.5 15.5 0.0016 19.1 1.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM57120.1 - 1.8e-06 28.0 17.4 0.00019 21.7 2.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM57120.1 - 0.00043 20.0 4.1 0.00043 20.0 4.1 3.0 2 2 0 2 2 2 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM57120.1 - 0.00055 20.2 7.5 0.0013 19.0 7.5 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFM57120.1 - 0.0039 17.5 6.6 0.45 10.9 0.2 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFM57120.1 - 0.0091 16.4 10.5 0.23 11.9 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM57120.1 - 0.01 16.1 8.4 0.025 14.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 KFM57120.1 - 0.011 15.3 5.8 0.59 9.8 0.1 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain zf-BED PF02892.15 KFM57120.1 - 0.011 15.7 8.3 0.18 11.9 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger zf-Sec23_Sec24 PF04810.15 KFM57120.1 - 0.21 11.6 9.2 0.56 10.3 0.9 2.5 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf_C2H2_ZHX PF18387.1 KFM57120.1 - 0.3 10.7 4.7 0.45 10.2 3.7 1.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn_Tnp_IS1595 PF12760.7 KFM57120.1 - 0.9 9.6 8.0 1.6 8.8 8.0 1.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.13 KFM57120.1 - 9.9 6.3 11.3 5.1 7.2 3.1 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DSPc PF00782.20 KFM57122.1 - 2.9e-36 124.2 0.1 4.6e-36 123.6 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM57122.1 - 0.02 14.5 0.3 0.041 13.4 0.2 1.6 1 1 0 1 1 1 0 Protein-tyrosine phosphatase PBP-Tp47_a PF14889.6 KFM57122.1 - 0.048 13.3 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Amidase PF01425.21 KFM57123.1 - 1e-77 262.0 0.0 1.3e-77 261.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Thioredoxin_8 PF13905.6 KFM57124.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like WD40 PF00400.32 KFM57129.1 - 3.8e-20 71.8 8.6 2.2e-06 28.3 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM57129.1 - 0.00011 22.4 0.3 0.43 10.9 0.2 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM57129.1 - 0.044 12.4 0.5 18 3.8 0.0 3.5 2 1 2 4 4 4 0 Nucleoporin Nup120/160 SUKH_6 PF14568.6 KFM57129.1 - 0.14 12.6 0.1 0.46 10.9 0.0 1.9 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall WD40_like PF17005.5 KFM57129.1 - 0.25 10.6 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain DDE_3 PF13358.6 KFM57130.1 - 6.3e-16 58.4 0.1 6.5e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57130.1 - 8.2e-16 58.0 6.5 1.5e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57130.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57130.1 - 0.0026 17.5 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57130.1 - 0.016 15.3 0.1 0.068 13.3 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57130.1 - 0.037 14.0 0.4 0.037 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM57132.1 - 5.9e-14 52.1 1.6 9.8e-14 51.4 1.6 1.4 1 0 0 1 1 1 1 Transposase MarR_2 PF12802.7 KFM57132.1 - 0.00018 21.3 0.6 0.01 15.7 0.0 2.4 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM57132.1 - 0.0014 18.5 1.1 0.0046 16.9 0.1 2.1 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM57132.1 - 0.0037 16.8 1.6 0.095 12.3 0.0 2.5 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 KFM57132.1 - 0.012 15.7 0.9 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix DUF1684 PF07920.11 KFM57132.1 - 0.038 14.3 0.1 0.078 13.3 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1684) HTH_26 PF13443.6 KFM57132.1 - 0.13 12.7 0.5 21 5.7 0.2 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain TrmB PF01978.19 KFM57132.1 - 0.15 12.0 0.1 2.3 8.1 0.0 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 KFM57132.1 - 6.1 6.8 6.9 16 5.4 0.0 3.3 3 1 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM57133.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57133.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 KFM57134.1 - 1.6e-65 221.1 0.1 1.6e-65 221.1 0.1 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57134.1 - 3.6e-47 160.8 0.0 7.8e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM57134.1 - 0.00052 19.4 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM57134.1 - 0.0019 17.0 1.2 0.0026 16.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFM57134.1 - 0.093 12.6 0.0 1.5 8.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Bromodomain PF00439.25 KFM57134.1 - 0.48 10.5 3.9 0.28 11.3 0.5 2.3 2 0 0 2 2 2 0 Bromodomain SOSSC PF15925.5 KFM57135.1 - 9.3e-21 75.0 0.9 1.2e-20 74.6 0.9 1.2 1 0 0 1 1 1 1 SOSS complex subunit C dCache_2 PF08269.11 KFM57135.1 - 0.13 11.4 1.4 0.14 11.3 1.4 1.0 1 0 0 1 1 1 0 Cache domain SUIM_assoc PF16619.5 KFM57135.1 - 0.19 11.8 4.4 0.32 11.1 3.4 2.0 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Septin PF00735.18 KFM57137.1 - 9.5e-11 41.5 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KFM57137.1 - 0.011 15.7 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 KFM57137.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 KFM57137.1 - 0.023 14.8 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KFM57137.1 - 0.092 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFM57137.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KFM57137.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFM57137.1 - 0.17 12.4 0.1 0.26 11.8 0.1 1.3 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KFM57137.1 - 0.22 10.5 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.18 KFM57139.1 - 7.9e-08 31.9 0.1 7.9e-08 31.9 0.1 2.3 2 1 0 2 2 2 1 Septin DUF3450 PF11932.8 KFM57139.1 - 0.35 10.1 15.2 0.66 9.2 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3332 PF11810.8 KFM57139.1 - 1.3 8.6 6.0 1.6 8.3 5.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) Exonuc_VII_L PF02601.15 KFM57139.1 - 2.8 7.4 13.3 3.2 7.2 13.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DASH_Dam1 PF08653.10 KFM57139.1 - 5.3 6.9 7.8 1.7 8.5 0.3 3.1 3 1 0 3 3 3 0 DASH complex subunit Dam1 OmpH PF03938.14 KFM57139.1 - 5.6 7.3 28.1 0.61 10.4 16.0 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) MADF_DNA_bdg PF10545.9 KFM57140.1 - 8.5e-17 61.3 0.4 1.3e-16 60.7 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3246 PF11596.8 KFM57140.1 - 0.06 12.8 0.6 0.073 12.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) LRAT PF04970.13 KFM57141.1 - 2.6e-18 66.5 0.2 1.1e-17 64.5 0.1 2.1 2 1 0 2 2 2 1 Lecithin retinol acyltransferase RNase_H PF00075.24 KFM57142.1 - 7.1e-16 58.7 0.3 2.4e-15 57.0 0.3 1.7 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM57142.1 - 6.9e-09 35.6 0.0 9.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like RT_RNaseH PF17917.1 KFM57142.1 - 0.043 14.1 0.1 0.12 12.6 0.1 1.8 1 1 1 2 2 2 0 RNase H-like domain found in reverse transcriptase BTB PF00651.31 KFM57143.1 - 1.5e-27 96.0 0.6 3e-27 95.0 0.6 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM57143.1 - 5.1e-06 26.5 0.1 0.009 16.1 0.0 2.9 2 0 0 2 2 2 2 BTB And C-terminal Kelch DnaJ_C PF01556.18 KFM57144.1 - 1.3e-07 31.8 0.0 1.3e-07 31.8 0.0 1.0 1 0 0 1 1 1 1 DnaJ C terminal domain CRAL_TRIO PF00650.20 KFM57145.1 - 3e-29 101.8 0.1 4.7e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM57145.1 - 8.9e-08 32.4 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM57145.1 - 0.0041 17.3 1.4 0.0069 16.5 0.2 2.1 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain TMEM189_B_dmain PF10520.9 KFM57145.1 - 0.012 15.8 0.3 0.018 15.2 0.3 1.2 1 0 0 1 1 1 0 B domain of TMEM189, localisation domain CRAL_TRIO PF00650.20 KFM57146.1 - 6.2e-29 100.8 0.1 1.2e-28 99.8 0.0 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM57146.1 - 2.3e-06 27.8 0.0 5.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM57146.1 - 0.0006 20.0 2.6 0.0018 18.4 2.6 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RyR PF02026.16 KFM57146.1 - 0.017 15.3 0.4 0.034 14.3 0.4 1.5 1 0 0 1 1 1 0 RyR domain DDE_3 PF13358.6 KFM57147.1 - 1.7e-27 95.9 0.0 5.3e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57147.1 - 1.3e-22 79.9 13.7 2.5e-15 56.4 6.5 3.2 3 0 0 3 3 3 2 Transposase HTH_32 PF13565.6 KFM57147.1 - 0.0012 19.4 1.5 0.0012 19.4 1.5 3.1 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57147.1 - 0.0098 15.7 0.3 0.19 11.6 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM57147.1 - 0.025 14.6 1.4 0.057 13.4 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix CRAL_TRIO PF00650.20 KFM57148.1 - 7.4e-33 113.5 0.0 1.3e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM57148.1 - 2.2e-08 34.4 0.0 5.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM57148.1 - 0.009 16.2 4.1 0.026 14.7 4.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RNase_T PF00929.24 KFM57148.1 - 0.14 12.7 0.6 0.24 11.9 0.6 1.3 1 0 0 1 1 1 0 Exonuclease CRAL_TRIO PF00650.20 KFM57149.1 - 5e-29 101.1 0.0 8.2e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM57149.1 - 5.5e-05 23.3 0.0 9.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM57149.1 - 0.021 15.0 1.1 0.046 13.9 1.1 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain RabGAP-TBC PF00566.18 KFM57151.1 - 3.4e-54 183.7 2.6 3.4e-54 183.7 2.6 2.4 3 1 0 3 3 3 1 Rab-GTPase-TBC domain DUF4988 PF16378.5 KFM57151.1 - 0.17 11.6 4.6 3 7.5 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function Borrelia_REV PF03978.13 KFM57151.1 - 0.41 10.6 12.6 0.56 10.1 5.4 2.6 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein FAM76 PF16046.5 KFM57151.1 - 2.2 7.6 12.0 9.4 5.5 12.0 2.0 1 1 0 1 1 1 0 FAM76 protein Csm1_N PF18504.1 KFM57151.1 - 3 8.2 13.4 5.1 7.5 6.8 2.9 1 1 1 2 2 2 0 Csm1 N-terminal domain Vfa1 PF08432.10 KFM57151.1 - 4 7.7 9.3 8.5 6.7 9.3 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF948 PF06103.11 KFM57151.1 - 4.1 7.7 4.8 14 6.1 4.8 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PH PF00169.29 KFM57152.1 - 5e-10 39.8 0.8 2.2e-09 37.8 0.1 2.2 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 KFM57152.1 - 1.3e-07 31.7 0.0 2.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFM57152.1 - 9.7e-05 22.6 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFM57152.1 - 0.0021 18.4 0.1 0.014 15.8 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain SNURF PF07192.11 KFM57152.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 SNURF/RPN4 protein PAN_1 PF00024.26 KFM57153.1 - 7e-10 38.7 8.4 5.1e-06 26.4 2.1 2.6 2 0 0 2 2 2 2 PAN domain BBP2 PF07642.11 KFM57153.1 - 0.0029 16.8 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative beta-barrel porin-2, OmpL-like. bbp2 Zona_pellucida PF00100.23 KFM57155.1 - 9.9e-05 22.3 0.0 0.0001 22.2 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain UPF0728 PF15092.6 KFM57157.1 - 0.011 15.6 0.3 2.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 Epimerase PF01370.21 KFM57157.1 - 0.018 14.5 1.1 0.036 13.5 1.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_S46 PF10459.9 KFM57157.1 - 0.44 9.1 14.0 0.5 8.9 14.0 1.1 1 0 0 1 1 1 0 Peptidase S46 FliT PF05400.13 KFM57157.1 - 0.75 10.6 7.8 1 10.2 0.4 3.0 2 2 0 2 2 2 0 Flagellar protein FliT DUF2529 PF10740.9 KFM57157.1 - 2.2 7.9 6.0 0.6 9.7 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2529) HTH_Tnp_Tc3_2 PF01498.18 KFM57158.1 - 2e-16 60.0 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57158.1 - 4.4e-12 46.0 0.0 7.2e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57159.1 - 2.4e-16 59.8 2.2 4.3e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57159.1 - 9.1e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM57160.1 - 3.3e-06 26.9 1.2 5e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) DDE_3 PF13358.6 KFM57161.1 - 6.7e-16 58.4 0.1 6.7e-15 55.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57161.1 - 8.7e-16 57.9 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57161.1 - 0.0008 20.0 1.5 0.0008 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57161.1 - 0.0033 17.2 0.1 0.13 12.1 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57161.1 - 0.018 15.1 0.1 0.071 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57161.1 - 0.039 14.0 0.4 0.039 14.0 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix 2_5_RNA_ligase2 PF13563.6 KFM57161.1 - 0.07 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily PIF1 PF05970.14 KFM57162.1 - 7e-43 147.2 0.6 8e-43 147.0 0.6 1.0 1 0 0 1 1 1 1 PIF1-like helicase CBM_14 PF01607.24 KFM57163.1 - 2.1e-09 37.4 5.8 3e-09 36.9 5.8 1.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Claudin_2 PF13903.6 KFM57163.1 - 0.065 13.0 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction CBM_14 PF01607.24 KFM57164.1 - 3e-10 40.1 5.8 6.2e-10 39.1 5.8 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Ank_2 PF12796.7 KFM57165.1 - 1.1e-41 141.3 9.9 5.7e-15 55.7 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFM57165.1 - 2.1e-40 135.5 9.9 3e-06 27.4 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KFM57165.1 - 1.2e-39 134.2 3.6 4.1e-09 36.8 0.0 5.2 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM57165.1 - 9.3e-37 120.9 8.2 9.2e-06 25.6 0.0 8.2 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFM57165.1 - 1.5e-36 124.0 10.7 4.7e-09 36.3 0.1 6.2 4 2 3 7 7 7 6 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KFM57165.1 - 0.27 11.1 3.2 9.6 6.2 0.2 2.6 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain Ank_2 PF12796.7 KFM57166.1 - 1.6e-33 115.1 8.6 1.9e-11 44.4 1.4 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM57166.1 - 5.5e-27 93.8 10.0 6.4e-07 29.8 0.1 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFM57166.1 - 1.2e-26 91.9 17.2 2.9e-07 30.6 0.1 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KFM57166.1 - 5.7e-24 83.9 15.7 8.9e-09 35.4 0.1 5.5 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM57166.1 - 3.1e-21 73.2 11.7 0.00029 21.0 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeat NTP_transf_5 PF14907.6 KFM57166.1 - 0.031 13.9 0.4 2.6 7.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase Ion_trans PF00520.31 KFM57167.1 - 4.4e-05 22.8 6.1 5e-05 22.7 6.1 1.0 1 0 0 1 1 1 1 Ion transport protein TMEM208_SND2 PF05620.11 KFM57167.1 - 0.032 14.0 0.5 0.039 13.7 0.5 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Ank_2 PF12796.7 KFM57169.1 - 1.6e-33 115.1 0.5 2.9e-16 59.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM57169.1 - 3.5e-32 110.3 2.8 5.5e-16 58.7 0.1 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM57169.1 - 6e-31 106.1 3.0 5.1e-08 33.0 0.2 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFM57169.1 - 5e-27 93.1 5.5 7.8e-07 29.3 0.2 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KFM57169.1 - 1.5e-25 86.5 3.1 4.3e-05 23.6 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Linker_histone PF00538.19 KFM57170.1 - 3.7e-13 49.6 0.1 3.9e-13 49.6 0.1 1.0 1 0 0 1 1 1 1 linker histone H1 and H5 family HTH_Tnp_Tc3_2 PF01498.18 KFM57171.1 - 2e-16 60.0 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57171.1 - 7.8e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57172.1 - 1.9e-06 27.7 0.0 2.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DRIM PF07539.12 KFM57172.1 - 0.17 10.2 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis HTH_Tnp_Tc3_2 PF01498.18 KFM57173.1 - 2.1e-23 82.3 6.6 1.8e-14 53.7 0.5 3.3 3 0 0 3 3 3 2 Transposase DDE_3 PF13358.6 KFM57173.1 - 7e-13 48.6 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_3 PF01381.22 KFM57173.1 - 0.0015 18.6 0.3 0.035 14.1 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_32 PF13565.6 KFM57173.1 - 0.0024 18.4 1.0 0.0024 18.4 1.0 3.3 2 1 1 3 3 3 1 Homeodomain-like domain PAX PF00292.18 KFM57173.1 - 0.0034 17.3 0.0 0.0084 16.0 0.0 1.6 1 1 0 1 1 1 1 'Paired box' domain MarR_2 PF12802.7 KFM57173.1 - 0.0077 16.1 0.4 0.096 12.6 0.0 2.9 2 1 1 3 3 3 1 MarR family HTH_23 PF13384.6 KFM57173.1 - 0.027 14.3 0.3 0.28 11.0 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 KFM57173.1 - 0.032 14.4 0.7 0.24 11.6 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM57173.1 - 0.067 13.2 1.4 0.13 12.3 0.0 2.2 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM57173.1 - 0.12 12.0 0.4 0.96 9.1 0.0 2.5 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding NACHT PF05729.12 KFM57174.1 - 1.3e-11 44.6 0.0 3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFM57174.1 - 8.5e-07 29.5 0.0 3.2e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM57174.1 - 3.7e-06 27.3 0.0 1.3e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFM57174.1 - 2.7e-05 24.2 0.0 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 KFM57174.1 - 0.0012 19.3 0.0 0.0055 17.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFM57174.1 - 0.0015 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KFM57174.1 - 0.0078 16.0 0.0 0.031 14.1 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase III, delta subunit 4HB PF17947.1 KFM57174.1 - 0.076 13.1 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 Four helical bundle domain ResIII PF04851.15 KFM57174.1 - 0.12 12.4 0.0 0.83 9.6 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Y_phosphatase PF00102.27 KFM57174.1 - 0.12 11.9 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase RNA_helicase PF00910.22 KFM57174.1 - 0.16 12.4 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase WD40 PF00400.32 KFM57175.1 - 0.0025 18.6 4.0 1.1 10.2 0.0 4.8 5 1 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 KFM57175.1 - 0.0059 15.3 0.1 1.6 7.2 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PMP22_Claudin PF00822.20 KFM57176.1 - 3.5e-12 46.5 3.8 5.4e-12 45.9 3.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFM57176.1 - 1.2e-11 44.8 4.2 1.2e-11 44.8 4.2 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.15 KFM57176.1 - 0.00022 21.3 7.6 0.00069 19.7 7.6 1.7 1 1 0 1 1 1 1 CD20-like family LtrA PF06772.11 KFM57176.1 - 0.0049 16.2 0.2 0.0064 15.8 0.2 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) PepSY_TM PF03929.16 KFM57176.1 - 0.012 15.3 0.4 0.016 14.9 0.2 1.3 1 1 0 1 1 1 0 PepSY-associated TM region DuoxA PF10204.9 KFM57176.1 - 0.016 14.3 4.8 0.021 13.9 4.8 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor DsbD_2 PF13386.6 KFM57176.1 - 0.031 14.2 7.5 0.042 13.8 7.5 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Claudin_3 PF06653.11 KFM57176.1 - 0.041 13.8 2.1 0.066 13.2 2.1 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF3671 PF12420.8 KFM57176.1 - 0.42 10.7 5.4 7.5 6.7 4.8 2.3 1 1 0 1 1 1 0 Protein of unknown function L_HMGIC_fpl PF10242.9 KFM57176.1 - 0.8 9.9 5.9 1.1 9.4 5.9 1.3 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein TssN PF17555.2 KFM57176.1 - 4.3 6.6 5.9 1.5 8.2 2.8 1.5 1 1 0 2 2 2 0 Type VI secretion system, TssN Claudin_2 PF13903.6 KFM57177.1 - 1.9e-19 70.2 2.5 2.4e-19 69.8 2.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFM57177.1 - 1.1e-11 44.9 4.8 2.5e-10 40.5 4.8 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 KFM57177.1 - 0.0014 18.5 2.5 0.0015 18.4 0.6 1.8 2 0 0 2 2 2 1 Amastin surface glycoprotein Claudin_3 PF06653.11 KFM57177.1 - 0.045 13.7 9.6 1.8 8.5 0.3 2.4 2 1 0 2 2 2 0 Tight junction protein, Claudin-like Wzy_C PF04932.15 KFM57177.1 - 0.84 9.3 9.1 1 9.0 1.2 3.0 2 1 1 3 3 3 0 O-Antigen ligase DUF3169 PF11368.8 KFM57177.1 - 1.6 8.2 5.7 1.3 8.5 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) ABC2_membrane_3 PF12698.7 KFM57177.1 - 1.8 7.6 6.6 0.32 10.0 2.4 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF202 PF02656.15 KFM57177.1 - 6.8 7.2 11.8 23 5.5 6.6 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DDE_3 PF13358.6 KFM57178.1 - 0.00046 20.0 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease VKOR PF07884.14 KFM57179.1 - 2.5e-22 79.4 6.2 2.8e-22 79.2 6.2 1.0 1 0 0 1 1 1 1 Vitamin K epoxide reductase family UQ_con PF00179.26 KFM57180.1 - 1.3e-27 96.2 0.0 3.9e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MIB_HERC2 PF06701.13 KFM57180.1 - 0.17 12.2 4.0 0.84 9.9 0.2 3.1 3 0 0 3 3 3 0 Mib_herc2 CENP-B_N PF04218.13 KFM57181.1 - 4.4e-16 58.2 0.6 6.3e-16 57.8 0.6 1.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFM57181.1 - 2.6e-05 23.9 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 KFM57181.1 - 0.0006 19.8 0.1 0.00096 19.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_psq PF05225.16 KFM57181.1 - 0.0028 17.3 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 KFM57181.1 - 0.0044 17.1 0.0 0.0075 16.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain IlvN PF07991.12 KFM57181.1 - 0.011 15.3 0.0 0.013 15.1 0.0 1.0 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HTH_38 PF13936.6 KFM57181.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57181.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_3 PF01381.22 KFM57181.1 - 0.014 15.5 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix Trp_repressor PF01371.19 KFM57181.1 - 0.043 14.0 0.1 0.054 13.6 0.1 1.2 1 0 0 1 1 1 0 Trp repressor protein HTH_Tnp_4 PF13613.6 KFM57181.1 - 0.078 12.7 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease zf-H2C2_5 PF13909.6 KFM57182.1 - 4.7e-08 32.6 1.3 4.7e-08 32.6 1.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM57182.1 - 4.6e-07 29.9 16.6 0.00049 20.4 5.6 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM57182.1 - 6.9e-07 29.4 0.3 6.9e-07 29.4 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM57182.1 - 6.5e-05 23.4 13.3 0.021 15.6 3.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFM57182.1 - 0.0056 17.3 6.6 0.0078 16.9 1.8 2.1 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats Elf1 PF05129.13 KFM57182.1 - 0.016 15.3 2.5 0.03 14.4 2.5 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like RNA_POL_M_15KD PF02150.16 KFM57182.1 - 0.067 13.1 2.7 8.3 6.4 0.7 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Scramblase PF03803.15 KFM57182.1 - 0.15 11.3 0.5 0.18 11.1 0.5 1.1 1 0 0 1 1 1 0 Scramblase zf-Sec23_Sec24 PF04810.15 KFM57182.1 - 0.64 10.1 7.8 3.5 7.7 0.1 2.6 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Desulfoferrod_N PF06397.12 KFM57182.1 - 0.71 9.5 0.1 0.71 9.5 0.1 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-C2H2_7 PF15269.6 KFM57182.1 - 1.2 9.3 9.6 2.3 8.3 2.2 2.2 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_11 PF16622.5 KFM57182.1 - 9.4 6.1 11.6 0.23 11.3 2.7 2.5 3 0 0 3 3 3 0 zinc-finger C2H2-type MIF4G PF02854.19 KFM57183.1 - 5.9e-30 104.5 10.0 1.5e-29 103.2 2.0 3.0 3 0 0 3 3 3 2 MIF4G domain MA3 PF02847.17 KFM57183.1 - 2.2e-22 79.1 0.2 9.2e-22 77.2 0.1 2.2 2 0 0 2 2 2 1 MA3 domain W2 PF02020.18 KFM57183.1 - 4.1e-15 55.7 0.2 4.1e-15 55.7 0.2 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Xpo1 PF08389.12 KFM57183.1 - 0.15 12.1 0.8 1.5 8.9 0.1 2.9 3 0 0 3 3 3 0 Exportin 1-like protein TGF_beta PF00019.20 KFM57185.1 - 1.3e-27 96.8 1.7 1.7e-27 96.4 0.4 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFM57185.1 - 9.9e-25 87.7 0.2 1.4e-24 87.2 0.2 1.2 1 0 0 1 1 1 1 TGF-beta propeptide NOT2_3_5 PF04153.18 KFM57185.1 - 0.045 13.8 0.1 0.086 12.9 0.1 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family Peptidase_S32 PF05579.13 KFM57187.1 - 0.1 11.8 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Radial_spoke PF04712.12 KFM57188.1 - 3.4e-22 79.1 0.4 3.4e-22 79.1 0.4 2.1 1 1 1 2 2 2 1 Radial spokehead-like protein DUF913 PF06025.12 KFM57188.1 - 0.19 10.7 0.7 0.16 10.9 0.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 KFM57188.1 - 0.35 10.0 1.8 0.33 10.1 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 KFM57188.1 - 0.37 8.7 0.8 0.32 8.9 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 KFM57188.1 - 1.9 8.2 13.1 2.2 8.0 13.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 KFM57188.1 - 3 8.0 8.1 4 7.6 8.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4746 PF15928.5 KFM57188.1 - 3.9 6.8 16.8 4.6 6.6 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 KFM57188.1 - 6.4 5.4 6.2 7.3 5.2 6.2 1.1 1 0 0 1 1 1 0 Presenilin Sulfotransfer_1 PF00685.27 KFM57189.1 - 2.8e-43 148.3 0.5 3.8e-43 147.9 0.5 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM57189.1 - 1.9e-10 41.5 0.1 1.3e-07 32.2 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family HTH_48 PF17906.1 KFM57191.1 - 1.1e-06 28.6 0.0 1.4e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Asparaginase_2 PF01112.18 KFM57192.1 - 1.2e-56 192.0 0.0 1.8e-56 191.4 0.0 1.3 1 1 0 1 1 1 1 Asparaginase Auts2 PF15336.6 KFM57192.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein MULE PF10551.9 KFM57193.1 - 0.018 15.5 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 MULE transposase domain DUF5539 PF17693.1 KFM57194.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5539) JLPA PF16668.5 KFM57195.1 - 0.048 12.7 0.2 0.048 12.7 0.2 1.0 1 0 0 1 1 1 0 Adhesin from Campylobacter Ig_2 PF13895.6 KFM57196.1 - 3.1e-10 40.3 0.9 0.00059 20.1 0.1 3.2 3 1 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM57196.1 - 3.1e-09 36.8 0.0 0.00085 19.3 0.0 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM57196.1 - 1.1e-07 32.3 1.7 0.023 15.3 0.1 3.3 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFM57196.1 - 0.0036 17.5 1.2 3.5 7.9 0.0 3.9 4 1 1 5 5 5 2 Immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM57197.1 - 4.8e-16 58.8 3.5 6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57197.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57197.1 - 2.2e-07 30.5 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57197.1 - 0.0027 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57197.1 - 0.059 13.5 2.8 0.094 12.9 0.4 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM57197.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain UPF0061 PF02696.14 KFM57199.1 - 1.1e-127 426.6 0.0 2.1e-127 425.8 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family BTB_3 PF16017.5 KFM57200.1 - 4.9e-50 168.0 0.0 7.8e-50 167.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KFM57200.1 - 0.0038 17.5 0.0 0.0085 16.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DX PF01666.17 KFM57201.1 - 0.021 15.3 1.7 0.021 15.3 1.7 2.0 2 0 0 2 2 2 0 DX module Nodulin_late PF07127.11 KFM57201.1 - 0.031 14.6 0.9 0.031 14.6 0.9 2.1 2 0 0 2 2 2 0 Late nodulin protein Colipase_C PF02740.14 KFM57201.1 - 0.091 13.0 2.3 0.091 13.0 2.3 1.8 2 0 0 2 2 2 0 Colipase, C-terminal domain Crust_neurohorm PF01147.17 KFM57203.1 - 9e-29 99.1 4.0 1.2e-28 98.6 4.0 1.2 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family RGM_C PF06534.13 KFM57203.1 - 0.05 13.1 0.9 0.073 12.6 0.9 1.4 1 1 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus Crust_neurohorm PF01147.17 KFM57205.1 - 2.3e-23 81.8 3.0 2.6e-23 81.6 3.0 1.0 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family Fibrillarin PF01269.17 KFM57206.1 - 3.8e-103 343.5 0.0 4.7e-103 343.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KFM57206.1 - 2.3e-05 24.2 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KFM57206.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HAUS-augmin3 PF14932.6 KFM57208.1 - 0.00025 20.7 9.2 0.00055 19.6 9.2 1.5 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 NDUFB11 PF17250.2 KFM57208.1 - 0.023 15.3 0.1 0.036 14.7 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit TssC PF17541.2 KFM57208.1 - 0.039 12.8 0.3 0.049 12.5 0.3 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB ABC_tran PF00005.27 KFM57209.1 - 3e-21 76.4 3.7 3.7e-21 76.1 0.1 2.7 3 0 0 3 3 3 1 ABC transporter ABC_tran_Xtn PF12848.7 KFM57209.1 - 8.4e-19 67.4 8.4 8.4e-19 67.4 8.4 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFM57209.1 - 4.3e-06 26.8 0.0 0.049 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM57209.1 - 0.021 14.3 1.3 0.12 11.8 1.3 2.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFM57209.1 - 0.034 14.0 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KFM57209.1 - 0.13 12.3 0.3 0.49 10.5 0.3 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KFM57209.1 - 0.17 12.2 0.5 10 6.4 0.0 3.3 4 1 0 4 4 4 0 AAA domain AAA_15 PF13175.6 KFM57209.1 - 9.6 5.8 15.2 1.9 8.1 2.8 3.1 2 1 0 2 2 2 0 AAA ATPase domain eIF2A PF08662.11 KFM57210.1 - 3.4e-27 95.6 0.0 5.4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Paramyxo_ncap PF00973.19 KFM57210.1 - 0.57 9.0 5.8 0.77 8.6 5.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Mito_fiss_reg PF05308.11 KFM57210.1 - 5.2 7.1 14.5 1.4 8.9 4.1 2.1 1 1 1 2 2 2 0 Mitochondrial fission regulator Imm41 PF15592.6 KFM57211.1 - 0.019 15.3 0.5 0.022 15.1 0.5 1.0 1 0 0 1 1 1 0 Immunity protein 41 Fer4_14 PF13394.6 KFM57212.1 - 0.036 14.2 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain eIF2A PF08662.11 KFM57213.1 - 0.054 13.4 1.0 0.3 10.9 0.2 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KFM57214.1 - 6.8e-34 115.4 0.8 1.6e-05 25.5 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat CSTF1_dimer PF16699.5 KFM57214.1 - 7.9e-28 96.0 0.1 1.5e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.7 KFM57214.1 - 8.5e-14 51.6 0.0 0.024 14.9 0.0 5.0 2 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM57214.1 - 2.4e-06 26.8 1.4 0.071 12.1 0.1 3.6 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFM57214.1 - 0.0027 16.3 0.0 0.05 12.1 0.0 2.3 2 1 0 2 2 2 1 Cytochrome D1 heme domain Frtz PF11768.8 KFM57214.1 - 0.0029 16.0 0.1 0.0091 14.4 0.1 1.8 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 KFM57214.1 - 0.12 11.5 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Trypsin PF00089.26 KFM57215.1 - 2.1e-64 217.3 0.1 2.5e-64 217.1 0.1 1.1 1 0 0 1 1 1 1 Trypsin Sushi PF00084.20 KFM57215.1 - 1.1e-07 32.3 0.2 1.2e-06 29.0 0.2 2.5 3 0 0 3 3 3 1 Sushi repeat (SCR repeat) DUF1986 PF09342.11 KFM57215.1 - 0.0016 18.8 0.0 0.0028 18.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PDZ PF00595.24 KFM57216.1 - 4.8e-06 26.8 0.0 5.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM57216.1 - 0.0077 16.1 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM57217.1 - 7.4e-12 45.5 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 KFM57217.1 - 2e-07 32.0 0.8 5.1e-07 30.7 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ_2 PF13180.6 KFM57217.1 - 3.3e-06 27.3 0.0 8.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM57217.1 - 0.00046 20.0 0.1 0.00084 19.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Acyl-CoA_dh_1 PF00441.24 KFM57218.1 - 5.2e-43 146.8 0.4 1e-42 145.9 0.0 1.7 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM57218.1 - 2.5e-37 128.0 0.2 1.2e-36 125.8 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM57218.1 - 1.3e-25 89.4 0.0 2.9e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM57218.1 - 3.3e-13 50.1 0.0 6.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Trimer_CC PF08954.11 KFM57218.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Trimerisation motif HpaB_N PF11794.8 KFM57218.1 - 0.1 12.2 0.1 0.36 10.4 0.1 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Proteasome PF00227.26 KFM57219.1 - 1.1e-56 191.4 0.0 1.4e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM57219.1 - 7.8e-14 51.0 0.1 1.3e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SoPB_HTH PF18090.1 KFM57219.1 - 0.056 13.6 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Centromere-binding protein HTH domain LSM PF01423.22 KFM57220.1 - 1.5e-19 69.4 0.0 1.9e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain WW PF00397.26 KFM57224.1 - 2e-19 69.4 6.1 1.3e-09 38.0 1.7 2.5 2 0 0 2 2 2 2 WW domain MBD PF01429.19 KFM57224.1 - 0.025 14.3 0.0 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Methyl-CpG binding domain TINF2_N PF14973.6 KFM57225.1 - 0.0086 16.4 0.6 0.018 15.4 0.6 1.6 1 0 0 1 1 1 1 TERF1-interacting nuclear factor 2 N-terminus Sigma_1s PF02454.16 KFM57225.1 - 0.047 13.7 1.0 5.6 7.0 0.0 2.9 1 1 2 3 3 3 0 Sigma 1s protein DUF244 PF03112.14 KFM57226.1 - 0.11 12.3 0.1 0.13 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Trypsin PF00089.26 KFM57227.1 - 2.6e-114 380.6 0.0 6.6e-65 219.0 0.1 2.4 2 0 0 2 2 2 2 Trypsin CUB PF00431.20 KFM57227.1 - 6.1e-34 116.7 0.2 5e-18 65.4 0.1 2.5 2 0 0 2 2 2 2 CUB domain Trypsin_2 PF13365.6 KFM57227.1 - 1.7e-09 38.7 0.0 0.00037 21.4 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM57227.1 - 5.1e-09 36.5 0.0 3.3e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) DUF316 PF03761.15 KFM57227.1 - 0.0065 16.1 0.0 4.7 6.7 0.0 3.2 3 0 0 3 3 3 2 Chymotrypsin family Peptidase-S1 CUB_2 PF02408.20 KFM57227.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 CUB-like domain La PF05383.17 KFM57228.1 - 2e-12 47.0 1.2 3.1e-12 46.4 1.2 1.3 1 0 0 1 1 1 1 La domain RNase_HII PF01351.18 KFM57228.1 - 0.12 12.2 0.4 0.11 12.3 0.4 1.1 1 0 0 1 1 1 0 Ribonuclease HII RRM_3 PF08777.11 KFM57229.1 - 8.8e-12 45.0 0.1 1.5e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif Gar1 PF04410.14 KFM57230.1 - 4.3e-35 120.7 0.0 5.5e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Kelch_5 PF13854.6 KFM57231.1 - 1.3e-45 152.7 27.0 2.1e-05 24.4 0.0 12.9 12 0 0 12 12 12 10 Kelch motif Kelch_4 PF13418.6 KFM57231.1 - 1e-43 147.1 19.9 1.2e-09 38.0 0.2 12.4 12 0 0 12 12 12 9 Galactose oxidase, central domain Kelch_1 PF01344.25 KFM57231.1 - 6.4e-38 128.1 11.8 4.8e-07 29.3 0.0 12.3 12 0 0 12 12 12 7 Kelch motif Kelch_6 PF13964.6 KFM57231.1 - 4.5e-35 118.8 26.6 1.7e-06 28.1 0.0 13.0 10 2 2 12 12 12 8 Kelch motif Kelch_3 PF13415.6 KFM57231.1 - 5.5e-29 99.9 19.7 2.8e-06 27.5 0.2 12.7 14 0 0 14 14 13 6 Galactose oxidase, central domain CUB PF00431.20 KFM57231.1 - 2.8e-23 82.4 0.1 2.8e-18 66.3 0.1 3.4 2 1 0 2 2 2 2 CUB domain Kelch_2 PF07646.15 KFM57231.1 - 1.3e-22 78.8 24.3 0.00053 19.9 0.0 12.9 13 0 0 13 13 13 6 Kelch motif Laminin_EGF PF00053.24 KFM57231.1 - 5.3e-11 42.5 78.5 2.7e-09 37.0 17.2 18.8 16 6 5 21 21 12 4 Laminin EGF domain EGF_3 PF12947.7 KFM57231.1 - 1.1e-09 38.3 13.3 1.1e-09 38.3 13.3 13.7 14 2 1 15 15 6 2 EGF domain PSI PF01437.25 KFM57231.1 - 8.5e-08 32.6 43.6 9.4e-07 29.3 10.4 17.7 17 2 0 17 17 11 7 Plexin repeat EGF_Tenascin PF18720.1 KFM57231.1 - 1.5e-06 28.1 5.7 1.5e-06 28.1 5.7 9.0 9 0 0 9 9 4 1 Tenascin EGF domain cEGF PF12662.7 KFM57231.1 - 0.0008 19.3 3.0 0.0008 19.3 3.0 8.7 9 0 0 9 9 7 1 Complement Clr-like EGF-like EGF PF00008.27 KFM57231.1 - 0.0028 17.9 8.7 0.0028 17.9 8.7 13.7 14 1 0 14 14 6 4 EGF-like domain DUF5074 PF16819.5 KFM57231.1 - 0.027 14.5 0.1 9 6.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) RPE65 PF03055.15 KFM57231.1 - 0.042 13.0 2.9 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 Retinal pigment epithelial membrane protein MFS_1 PF07690.16 KFM57233.1 - 1.3e-20 73.6 14.6 5.9e-17 61.6 0.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFM57233.1 - 0.00033 19.3 28.9 0.00055 18.6 10.3 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.8 KFM57233.1 - 0.053 12.2 22.4 0.011 14.4 5.8 2.7 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like RVT_1 PF00078.27 KFM57234.1 - 5.4e-44 150.3 0.0 1.2e-43 149.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MCM PF00493.23 KFM57235.1 - 1.6e-100 334.8 0.0 2.5e-100 334.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFM57235.1 - 3.1e-39 133.7 0.0 6.6e-39 132.6 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFM57235.1 - 1.1e-26 93.1 0.4 3.1e-26 91.6 0.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFM57235.1 - 1e-18 67.9 3.6 1e-18 67.9 3.6 2.3 3 0 0 3 3 2 1 MCM N-terminal domain AAA_5 PF07728.14 KFM57235.1 - 2.2e-08 34.2 0.0 7.1e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFM57235.1 - 5.1e-08 32.6 0.0 2.2e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFM57235.1 - 5.2e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM57235.1 - 0.0012 18.6 0.2 1.3 8.7 0.0 3.4 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA PF00004.29 KFM57235.1 - 0.06 13.8 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-CHY PF05495.12 KFM57235.1 - 0.1 13.1 0.2 0.26 11.8 0.2 1.6 1 0 0 1 1 1 0 CHY zinc finger ATP-sulfurylase PF01747.17 KFM57235.1 - 0.11 12.0 0.1 18 4.7 0.0 2.4 2 0 0 2 2 2 0 ATP-sulfurylase Elf1 PF05129.13 KFM57235.1 - 0.15 12.2 0.7 0.47 10.5 0.3 2.1 2 0 0 2 2 1 0 Transcription elongation factor Elf1 like AAA_22 PF13401.6 KFM57235.1 - 0.15 12.4 0.5 9.1 6.6 0.0 3.4 3 1 1 4 4 4 0 AAA domain TB PF00683.17 KFM57236.1 - 2.3e-12 46.5 9.4 5.1e-12 45.3 9.4 1.6 1 0 0 1 1 1 1 TB domain EGF_CA PF07645.15 KFM57236.1 - 1.7e-09 37.7 9.5 1.7e-09 37.7 9.5 3.2 2 1 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 KFM57236.1 - 1.1e-05 25.6 4.1 1.1e-05 25.6 4.1 3.0 2 1 1 3 3 3 1 EGF-like domain cEGF PF12662.7 KFM57236.1 - 1.3e-05 25.0 0.8 1.3e-05 25.0 0.8 3.6 4 0 0 4 4 4 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFM57236.1 - 0.00014 22.1 8.6 0.00014 22.1 8.6 2.5 3 1 0 3 3 3 1 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFM57236.1 - 0.0024 18.4 7.0 0.0024 18.4 7.0 3.4 3 0 0 3 3 3 1 Human growth factor-like EGF EGF_CA PF07645.15 KFM57237.1 - 2.9e-51 171.4 92.0 3.4e-12 46.4 8.3 6.5 6 0 0 6 6 6 6 Calcium-binding EGF domain cEGF PF12662.7 KFM57237.1 - 7.7e-41 137.6 49.5 1.3e-08 34.6 1.3 7.3 6 0 0 6 6 6 6 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFM57237.1 - 2.7e-23 82.0 89.3 1.4e-05 25.2 6.8 7.0 6 1 1 7 7 7 6 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFM57237.1 - 2.8e-19 69.1 88.2 0.00044 20.5 6.8 7.2 7 0 0 7 7 7 6 EGF-like domain EGF_3 PF12947.7 KFM57237.1 - 1.2e-18 66.9 76.4 0.00024 21.2 4.8 7.4 7 0 0 7 7 7 6 EGF domain TB PF00683.17 KFM57237.1 - 5e-17 61.4 10.9 3e-16 58.9 10.9 2.4 1 0 0 1 1 1 1 TB domain hEGF PF12661.7 KFM57237.1 - 4.4e-16 58.9 89.1 0.0006 20.3 7.2 8.5 8 0 0 8 8 8 6 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 KFM57237.1 - 7.3e-11 42.2 81.4 0.0054 17.0 9.7 7.4 5 1 1 6 6 6 4 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 KFM57237.1 - 0.037 14.1 2.9 0.037 14.1 2.9 7.4 6 1 1 7 7 7 0 MSP1 EGF domain 1 EGF_2 PF07974.13 KFM57237.1 - 1.7 9.1 98.4 0.5 10.8 4.1 8.2 6 2 1 7 7 7 0 EGF-like domain EGF_CA PF07645.15 KFM57238.1 - 6.4e-47 157.5 105.7 1.9e-09 37.6 9.1 6.7 7 0 0 7 7 7 6 Calcium-binding EGF domain cEGF PF12662.7 KFM57238.1 - 3.2e-37 126.1 58.0 3.9e-07 29.9 3.5 8.1 7 0 0 7 7 7 7 Complement Clr-like EGF-like EGF_3 PF12947.7 KFM57238.1 - 5.4e-25 87.3 83.6 1.2e-12 47.8 8.6 8.1 5 2 1 7 7 7 6 EGF domain EGF PF00008.27 KFM57238.1 - 1.1e-22 79.9 93.2 1.7e-06 28.2 7.1 8.2 7 1 0 7 7 7 6 EGF-like domain TB PF00683.17 KFM57238.1 - 5e-16 58.2 8.1 5e-16 58.2 8.1 2.7 2 0 0 2 2 2 1 TB domain FXa_inhibition PF14670.6 KFM57238.1 - 6.6e-12 45.5 99.8 8.8e-05 22.7 8.7 7.6 7 1 1 8 8 8 6 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFM57238.1 - 4.8e-08 33.3 57.4 0.00016 22.2 2.4 10.4 13 0 0 13 13 13 5 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 KFM57238.1 - 2.4e-06 27.5 5.7 2.4e-06 27.5 5.7 6.6 6 0 0 6 6 6 4 MSP1 EGF domain 1 EGF_2 PF07974.13 KFM57238.1 - 0.38 11.2 93.2 0.16 12.4 4.5 8.4 7 2 1 8 8 8 0 EGF-like domain EGF_CA PF07645.15 KFM57239.1 - 3e-30 104.1 33.9 3.3e-10 40.0 2.5 3.1 3 0 0 3 3 3 3 Calcium-binding EGF domain cEGF PF12662.7 KFM57239.1 - 2.2e-25 88.2 27.2 4.3e-10 39.3 1.3 4.6 4 0 0 4 4 4 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFM57239.1 - 7.9e-18 64.4 40.9 5.4e-09 36.2 5.2 3.3 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFM57239.1 - 5.2e-10 39.3 28.1 0.0014 18.8 3.5 3.9 3 1 0 3 3 3 3 EGF domain hEGF PF12661.7 KFM57239.1 - 1.1e-09 38.5 38.3 0.0012 19.3 8.0 4.3 4 0 0 4 4 4 3 Human growth factor-like EGF EGF PF00008.27 KFM57239.1 - 1.9e-09 37.6 32.4 0.0016 18.7 6.4 3.8 3 1 0 3 3 3 3 EGF-like domain Plasmod_Pvs28 PF06247.11 KFM57239.1 - 4.7e-05 23.6 26.0 0.0071 16.6 3.5 3.7 2 1 1 3 3 3 3 Pvs28 EGF domain EGF_2 PF07974.13 KFM57239.1 - 0.00061 20.1 35.9 0.29 11.5 10.3 3.9 2 2 1 3 3 3 3 EGF-like domain EGF_MSP1_1 PF12946.7 KFM57239.1 - 0.013 15.5 20.0 0.13 12.3 5.1 3.5 3 0 0 3 3 3 0 MSP1 EGF domain 1 EGF_CA PF07645.15 KFM57240.1 - 1.8e-109 357.7 213.8 5e-12 45.8 4.6 15.5 15 2 1 16 16 16 13 Calcium-binding EGF domain cEGF PF12662.7 KFM57240.1 - 1.3e-67 223.3 134.2 8.3e-10 38.4 1.2 17.2 16 1 0 16 16 16 14 Complement Clr-like EGF-like TB PF00683.17 KFM57240.1 - 5.5e-53 176.5 58.2 3.7e-16 58.6 8.5 6.1 4 0 0 4 4 4 4 TB domain EGF PF00008.27 KFM57240.1 - 2.7e-39 133.1 199.0 1.6e-06 28.3 4.3 16.9 18 1 0 18 18 18 13 EGF-like domain hEGF PF12661.7 KFM57240.1 - 5.2e-34 115.7 212.5 0.00017 22.1 6.8 17.7 19 1 0 19 19 19 13 Human growth factor-like EGF FXa_inhibition PF14670.6 KFM57240.1 - 8e-29 99.6 206.8 0.0001 22.5 6.7 15.8 15 1 1 16 16 16 13 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KFM57240.1 - 2.5e-23 82.1 143.6 0.0071 16.6 1.4 15.1 12 2 2 14 14 14 13 Pvs28 EGF domain EGF_3 PF12947.7 KFM57240.1 - 3.7e-21 75.0 179.4 0.0026 17.9 2.3 17.1 14 3 1 17 17 17 13 EGF domain MAAL_C PF07476.11 KFM57240.1 - 0.1 11.7 0.4 0.22 10.6 0.4 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Bcl-2 PF00452.19 KFM57241.1 - 9e-27 93.7 0.2 4.3e-26 91.5 0.1 1.9 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family DBI_PRT PF02277.17 KFM57241.1 - 0.021 14.0 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyltransferase FliD_C PF07195.12 KFM57241.1 - 0.13 11.6 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Sel1 PF08238.12 KFM57242.1 - 1.1e-12 48.1 1.2 4e-08 33.7 0.2 2.4 2 0 0 2 2 2 2 Sel1 repeat Spore_permease PF03845.13 KFM57242.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Spore germination protein EF-hand_1 PF00036.32 KFM57243.1 - 1.1e-28 96.6 12.6 1.4e-08 33.7 0.1 5.8 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 KFM57243.1 - 2.9e-26 89.1 7.6 6e-06 25.8 0.1 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 KFM57243.1 - 1.6e-25 89.3 7.4 4.7e-11 43.0 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KFM57243.1 - 1.7e-24 85.4 6.7 2.4e-11 43.3 0.0 4.6 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KFM57243.1 - 7.7e-19 66.3 10.4 5.8e-05 22.4 0.0 5.3 5 1 0 5 5 5 3 EF hand EF-hand_9 PF14658.6 KFM57243.1 - 2.3e-07 31.0 0.1 0.0061 16.9 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_2 PF09068.11 KFM57243.1 - 0.0047 17.1 0.0 2.1 8.5 0.0 3.2 3 1 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 KFM57243.1 - 0.012 15.5 3.1 0.016 15.1 0.3 2.3 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KFM57243.1 - 0.033 15.0 0.7 0.22 12.4 0.2 2.2 1 1 1 2 2 2 0 EF-hand domain GUN4 PF05419.12 KFM57243.1 - 0.043 13.9 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 GUN4-like EF-hand_10 PF14788.6 KFM57243.1 - 0.1 12.5 0.3 7.6 6.5 0.0 3.1 3 0 0 3 3 3 0 EF hand PGI PF00342.19 KFM57245.1 - 1.1e-124 416.7 0.3 1.3e-124 416.5 0.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Hydrolase_6 PF13344.6 KFM57245.1 - 0.14 12.3 0.1 1.3 9.2 0.1 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HTH_Tnp_Tc3_2 PF01498.18 KFM57246.1 - 4.6e-16 58.8 5.9 1.5e-15 57.2 6.5 1.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57246.1 - 1.3e-15 57.4 0.1 7e-15 55.0 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM57246.1 - 0.00017 21.2 0.8 0.12 12.2 0.0 4.3 4 0 0 4 4 4 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57246.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 3.6 3 1 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 KFM57246.1 - 0.0061 16.3 1.9 0.17 11.6 0.1 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_28 PF13518.6 KFM57246.1 - 0.0073 16.4 0.6 0.067 13.3 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM57246.1 - 0.026 14.5 2.6 0.036 14.1 0.4 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM57246.1 - 0.043 13.9 0.1 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase E1_dh PF00676.20 KFM57247.1 - 3.9e-119 397.1 0.1 4.6e-119 396.8 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFM57247.1 - 0.0011 18.3 0.2 0.0026 17.0 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KFM57247.1 - 0.0061 16.4 0.5 0.013 15.3 0.5 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1451 PF07295.11 KFM57247.1 - 0.16 12.0 0.4 0.27 11.3 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain F-box-like PF12937.7 KFM57248.1 - 5.7e-17 61.3 0.7 9.7e-17 60.6 0.7 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM57248.1 - 4.5e-09 36.0 0.2 7.5e-09 35.3 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFM57248.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 F-box REJ PF02010.15 KFM57250.1 - 2.1e-16 59.8 0.5 9e-16 57.7 0.5 1.8 1 1 0 1 1 1 1 REJ domain GPS PF01825.21 KFM57250.1 - 3.7e-07 30.6 0.1 7.2e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Podoplanin PF05808.11 KFM57250.1 - 0.0055 16.8 0.8 0.011 15.9 0.8 1.4 1 0 0 1 1 1 1 Podoplanin Adeno_E3_CR2 PF02439.15 KFM57250.1 - 0.007 16.1 1.6 0.016 14.9 1.6 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KFM57250.1 - 0.018 14.9 1.0 0.044 13.7 1.0 1.5 1 0 0 1 1 1 0 Syndecan domain Amnionless PF14828.6 KFM57250.1 - 0.13 11.1 0.1 0.25 10.1 0.1 1.4 1 0 0 1 1 1 0 Amnionless DUF3149 PF11346.8 KFM57250.1 - 3.3 7.4 7.0 7.3 6.3 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) HTH_Tnp_Tc3_2 PF01498.18 KFM57251.1 - 5.1e-16 58.7 3.5 6.1e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57251.1 - 4.6e-14 52.4 0.0 8.6e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57251.1 - 5.1e-07 29.4 1.6 7.5e-07 28.8 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57251.1 - 0.0025 17.6 0.6 0.008 15.9 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain Methyltrans_Mon PF14314.6 KFM57251.1 - 0.1 10.6 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase HTH_32 PF13565.6 KFM57251.1 - 2.1 9.0 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain GPCR_chapero_1 PF11904.8 KFM57252.1 - 6.5e-12 45.5 6.1 4.9e-11 42.6 1.8 2.0 1 1 1 2 2 2 2 GPCR-chaperone GPCR_chapero_1 PF11904.8 KFM57253.1 - 1.2e-35 123.4 0.1 1.6e-35 123.0 0.1 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 KFM57253.1 - 8.5e-11 42.3 0.0 1.5e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM57253.1 - 2.8e-08 33.8 0.0 1.2e-07 31.9 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KFM57253.1 - 5.5e-08 32.5 0.0 2.8e-05 24.2 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KFM57253.1 - 8.8e-08 32.3 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM57253.1 - 6.4e-07 29.8 0.0 1.4e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Leucyl-specific PF14795.6 KFM57253.1 - 0.0092 16.0 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 Leucine-tRNA synthetase-specific domain ABC_tran PF00005.27 KFM57254.1 - 1.8e-16 60.9 0.0 3.6e-16 59.9 0.0 1.5 2 0 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 KFM57254.1 - 1e-05 25.5 0.1 1.8e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KFM57254.1 - 2.9e-05 24.5 0.0 3.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KFM57254.1 - 5.6e-05 22.3 0.0 6.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KFM57254.1 - 0.00029 20.5 0.2 0.00048 19.8 0.2 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KFM57254.1 - 0.00051 20.3 0.1 0.00089 19.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM57254.1 - 0.00062 20.3 0.0 0.00084 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KFM57254.1 - 0.0011 18.6 0.1 0.0015 18.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 KFM57254.1 - 0.0029 17.2 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain PIF1 PF05970.14 KFM57254.1 - 0.0039 16.4 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_28 PF13521.6 KFM57254.1 - 0.0043 17.3 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFM57254.1 - 0.0062 16.6 0.2 0.013 15.6 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KFM57254.1 - 0.0084 16.3 0.0 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM57254.1 - 0.0087 15.4 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 KFM57254.1 - 0.0094 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFM57254.1 - 0.011 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 KFM57254.1 - 0.012 16.1 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KFM57254.1 - 0.017 14.9 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 KFM57254.1 - 0.021 14.6 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 KFM57254.1 - 0.023 15.2 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KFM57254.1 - 0.024 14.7 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA PF00004.29 KFM57254.1 - 0.024 15.1 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFM57254.1 - 0.024 14.5 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 KFM57254.1 - 0.037 13.9 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KFM57254.1 - 0.048 13.7 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFM57254.1 - 0.048 13.4 0.1 0.068 12.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFM57254.1 - 0.053 13.6 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFM57254.1 - 0.058 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 KFM57254.1 - 0.085 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain APS_kinase PF01583.20 KFM57254.1 - 0.086 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Septin PF00735.18 KFM57254.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Septin SMC_N PF02463.19 KFM57254.1 - 0.13 11.6 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 KFM57254.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KFM57254.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 KFM57254.1 - 0.15 10.9 0.1 0.25 10.1 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Adaptin_N PF01602.20 KFM57256.1 - 1.9e-169 564.6 15.8 2.5e-169 564.2 15.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP3B1_C PF14796.6 KFM57256.1 - 2.2e-42 144.8 0.3 2.2e-42 144.8 0.3 2.2 2 0 0 2 2 2 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Cnd1 PF12717.7 KFM57256.1 - 2.4e-25 89.4 11.7 8.6e-22 77.9 0.6 3.6 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM57256.1 - 1.5e-10 41.3 0.9 3.1e-06 27.5 0.2 4.4 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.22 KFM57256.1 - 3.6e-08 33.0 0.7 1.1 9.7 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KFM57256.1 - 6.9e-05 23.2 2.6 3 8.4 0.0 5.0 4 1 1 5 5 5 2 HEAT-like repeat Ribosomal_L18 PF17135.4 KFM57256.1 - 0.072 12.5 0.1 0.24 10.8 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Dsh_C PF12316.8 KFM57256.1 - 3.4 8.0 19.9 1.8 8.9 11.5 2.3 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal SCAMP PF04144.13 KFM57257.1 - 1.4e-64 217.6 16.2 1.7e-64 217.3 16.2 1.1 1 0 0 1 1 1 1 SCAMP family Wtap PF17098.5 KFM57257.1 - 0.064 13.2 0.8 0.11 12.4 0.8 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family dUTPase PF00692.19 KFM57258.1 - 1.6e-47 160.4 0.0 1.8e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 dUTPase Sulfotransfer_1 PF00685.27 KFM57259.1 - 6.1e-37 127.5 0.1 6.9e-37 127.4 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM57259.1 - 1.9e-09 38.2 0.0 2.6e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family AAA_22 PF13401.6 KFM57259.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain IF2_N PF04760.15 KFM57259.1 - 0.13 12.1 0.3 0.24 11.2 0.3 1.5 1 1 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region CSTF_C PF14304.6 KFM57260.1 - 1.2e-20 72.8 10.3 2.1e-20 72.0 10.3 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 KFM57261.1 - 3.7e-28 97.8 1.3 6.6e-28 97.0 1.3 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KFM57261.1 - 7.3e-27 93.0 0.0 1.5e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM57261.1 - 0.0079 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 KFM57261.1 - 0.021 15.1 0.0 0.9 9.8 0.0 2.3 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KFM57261.1 - 0.021 14.6 0.0 0.054 13.3 0.0 1.7 1 1 0 1 1 1 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 KFM57261.1 - 0.044 13.6 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif HTH_Tnp_Tc3_2 PF01498.18 KFM57262.1 - 1.6e-09 37.8 1.1 2.2e-09 37.4 1.1 1.2 1 0 0 1 1 1 1 Transposase WD40 PF00400.32 KFM57263.1 - 1.7e-20 72.9 19.8 0.0065 17.3 1.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM57263.1 - 8.5e-09 35.6 0.0 0.19 12.0 0.0 4.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM57263.1 - 0.0029 17.0 0.0 3.6 6.8 0.1 2.7 2 1 0 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 KFM57263.1 - 0.014 14.0 0.0 3.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KFM57263.1 - 0.042 12.6 0.0 0.2 10.4 0.0 2.1 1 1 0 1 1 1 0 Nup133 N terminal like Nup160 PF11715.8 KFM57263.1 - 0.059 12.0 0.4 1.9 7.0 0.0 2.1 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Glyoxal_oxid_N PF07250.11 KFM57263.1 - 0.15 11.2 0.4 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus CRAL_TRIO PF00650.20 KFM57264.1 - 1.5e-27 96.3 0.1 2.7e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM57264.1 - 2.3e-07 30.9 0.3 6.1e-07 29.5 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM57264.1 - 0.0045 17.1 0.3 0.0069 16.5 0.3 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM57265.1 - 6e-28 97.6 0.1 1.3e-27 96.5 0.1 1.5 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM57265.1 - 2.3e-07 30.9 1.0 2.3e-07 30.9 1.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM57265.1 - 0.0027 17.8 0.3 0.0043 17.2 0.3 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain KH_10 PF17905.1 KFM57265.1 - 0.02 15.3 1.4 2.6 8.5 0.1 3.4 3 1 0 3 3 3 0 GLD-3 KH domain 5 Tub PF01167.18 KFM57265.1 - 0.027 14.2 0.1 0.039 13.7 0.1 1.1 1 0 0 1 1 1 0 Tub family HTH_Tnp_Tc3_2 PF01498.18 KFM57267.1 - 5e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57267.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57267.1 - 1.6e-07 31.0 1.2 7.2e-07 28.9 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57267.1 - 0.0026 17.5 0.6 0.0077 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57267.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57268.1 - 2.4e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57268.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57269.1 - 1.9e-16 60.1 2.2 5.2e-16 58.6 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57269.1 - 1.1e-13 51.2 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57269.1 - 3.1e-07 30.0 0.8 1.4e-06 27.9 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57269.1 - 0.0022 17.7 0.3 0.0063 16.3 0.3 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57269.1 - 0.01 15.9 0.3 0.032 14.4 0.3 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM57269.1 - 1.1 10.0 14.7 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain B56 PF01603.20 KFM57270.1 - 2.5e-87 293.5 7.5 2.8e-87 293.4 7.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) NAD1 PF18778.1 KFM57270.1 - 0.0021 18.1 1.8 0.19 11.8 0.6 2.1 2 0 0 2 2 2 2 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KFM57270.1 - 0.0084 16.2 0.7 1.1 9.3 0.3 2.1 2 0 0 2 2 2 2 APOBEC2 DUF4372 PF14294.6 KFM57270.1 - 0.1 12.8 0.4 1.6 8.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) DUF2258 PF10015.9 KFM57270.1 - 0.15 12.2 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Gelsolin PF00626.22 KFM57274.1 - 4.4e-66 218.8 6.7 9.1e-16 57.5 0.1 6.4 6 0 0 6 6 6 6 Gelsolin repeat LRR_8 PF13855.6 KFM57274.1 - 2.3e-20 72.1 28.2 2.4e-09 36.8 4.3 4.7 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFM57274.1 - 1.6e-18 66.5 36.3 6.3e-06 26.4 1.5 6.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM57274.1 - 9.5e-06 25.5 24.5 3.9 8.4 0.2 8.4 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 KFM57274.1 - 6.8e-05 22.4 2.6 6.8e-05 22.4 2.6 3.5 2 1 1 3 3 3 2 Leucine-rich repeat CutA1 PF03091.15 KFM57274.1 - 0.056 13.3 1.1 40 4.1 0.0 3.9 4 0 0 4 4 4 0 CutA1 divalent ion tolerance protein WD40 PF00400.32 KFM57277.1 - 2.8e-06 27.9 0.4 9e-06 26.3 0.1 1.9 2 1 0 2 2 2 1 WD domain, G-beta repeat WD40 PF00400.32 KFM57278.1 - 0.00057 20.6 0.7 0.18 12.7 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Kelch_6 PF13964.6 KFM57278.1 - 0.031 14.6 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 Kelch motif HPS3_N PF14761.6 KFM57278.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 HTH_Tnp_Tc3_2 PF01498.18 KFM57279.1 - 2.5e-16 59.7 2.2 5.1e-16 58.7 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57279.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_H PF00075.24 KFM57279.1 - 0.0058 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 RNase H HTH_Tnp_Tc3_2 PF01498.18 KFM57280.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57280.1 - 8.6e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57281.1 - 8e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57281.1 - 2e-15 56.8 0.0 5.9e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM57281.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57281.1 - 0.0041 16.9 0.3 0.12 12.2 0.0 2.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57281.1 - 0.017 15.2 0.1 0.066 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57281.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix GAS2 PF02187.17 KFM57283.1 - 3.1e-25 88.0 0.5 5.4e-25 87.3 0.5 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain COX6A PF02046.15 KFM57284.1 - 7.4e-16 58.6 0.1 8.6e-16 58.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa HTH_Tnp_Tc3_2 PF01498.18 KFM57285.1 - 7.1e-10 39.0 0.2 1.7e-09 37.8 0.2 1.7 1 0 0 1 1 1 1 Transposase Suv3_N PF18114.1 KFM57285.1 - 0.0041 17.2 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 Suv3 helical N-terminal domain HTH_Tnp_ISL3 PF13542.6 KFM57285.1 - 0.0041 16.5 0.1 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 KFM57285.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 KFM57285.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain CENP-B_N PF04218.13 KFM57285.1 - 0.013 15.2 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 KFM57285.1 - 0.036 14.2 0.0 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM57285.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 KFM57285.1 - 0.077 13.0 0.1 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix Kelch_1 PF01344.25 KFM57287.1 - 1.7e-31 107.5 1.1 9.4e-18 63.5 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 KFM57287.1 - 9e-24 82.9 0.1 3.2e-14 52.6 0.0 2.2 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.15 KFM57287.1 - 2.8e-14 52.4 0.3 3.5e-07 29.9 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 KFM57287.1 - 4.5e-14 52.2 0.3 1.2e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KFM57287.1 - 5.6e-09 36.1 0.9 1.9e-05 24.8 0.1 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM57287.1 - 2.7e-08 33.6 1.2 2.1e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Kelch motif DDE_3 PF13358.6 KFM57288.1 - 0.0017 18.1 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase_Tyr PF07714.17 KFM57289.1 - 1.4e-14 54.0 0.1 2e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM57289.1 - 2.5e-10 40.2 0.0 4.4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57290.1 - 6.5e-40 137.0 0.0 7.3e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM57290.1 - 2.2e-14 53.5 0.0 2.7e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DSPc PF00782.20 KFM57291.1 - 5.5e-26 91.0 0.0 7.3e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KFM57291.1 - 0.00064 20.0 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KFM57291.1 - 0.0018 17.9 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MEDS PF14417.6 KFM57291.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain HTH_23 PF13384.6 KFM57292.1 - 2.8e-08 33.3 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KFM57292.1 - 8.3e-07 28.6 0.1 9.2e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 KFM57292.1 - 3.2e-06 27.0 0.1 4.2e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_50 PF18024.1 KFM57292.1 - 2.1e-05 24.1 0.2 2.8e-05 23.6 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KFM57292.1 - 2.5e-05 24.0 0.2 3.4e-05 23.5 0.2 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM57292.1 - 2.8e-05 23.4 0.0 3.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KFM57292.1 - 3.8e-05 23.7 0.0 5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM57292.1 - 0.00035 20.0 0.1 0.00044 19.7 0.1 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 UPF0122 PF04297.14 KFM57292.1 - 0.00061 20.0 0.0 0.00069 19.8 0.0 1.1 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_24 PF13412.6 KFM57292.1 - 0.0016 18.0 0.1 0.0018 17.8 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_IS630 PF01710.16 KFM57292.1 - 0.0022 18.0 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Transposase Mor PF08765.11 KFM57292.1 - 0.0087 16.0 0.4 0.01 15.8 0.4 1.2 1 0 0 1 1 1 1 Mor transcription activator family HTH_7 PF02796.15 KFM57292.1 - 0.0098 16.0 0.2 0.016 15.3 0.2 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain of resolvase TnsD PF15978.5 KFM57292.1 - 0.0098 14.9 0.1 0.0098 14.9 0.1 1.0 1 0 0 1 1 1 1 Tn7-like transposition protein D HTH_1 PF00126.27 KFM57292.1 - 0.011 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_1 PF01527.20 KFM57292.1 - 0.011 16.0 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 0 Transposase DUF3791 PF12668.7 KFM57292.1 - 0.034 14.2 0.1 0.05 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) HTH_40 PF14493.6 KFM57292.1 - 0.04 14.4 0.1 0.045 14.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 KFM57292.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix HTH_Tnp_Tc3_2 PF01498.18 KFM57293.1 - 1.9e-16 60.1 2.2 4.7e-16 58.8 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57293.1 - 8.1e-13 48.4 0.0 1.6e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r4_2 PF08281.12 KFM57293.1 - 0.022 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_Tc3_2 PF01498.18 KFM57294.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57294.1 - 2.5e-13 50.0 0.0 4.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57294.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57294.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57294.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57295.1 - 2.4e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57295.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57296.1 - 5.5e-16 58.6 0.1 6.1e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57296.1 - 8.1e-16 58.0 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57296.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57296.1 - 0.0026 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57296.1 - 0.015 15.4 0.1 0.066 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57296.1 - 0.035 14.1 2.6 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM57297.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57297.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease NPV_P10 PF05531.12 KFM57299.1 - 0.05 14.1 0.2 0.064 13.7 0.1 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Vinculin PF01044.19 KFM57300.1 - 5e-09 35.0 8.8 5.8e-09 34.8 1.4 2.0 1 1 0 2 2 2 2 Vinculin family HTH_Tnp_Tc3_2 PF01498.18 KFM57301.1 - 3.8e-16 59.1 3.0 6.4e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57301.1 - 1.5e-13 50.7 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57301.1 - 3.2e-07 30.0 1.6 7.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57301.1 - 0.0029 17.3 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57301.1 - 2.8 8.6 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57302.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57302.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57304.1 - 1.4e-13 50.8 0.0 5.7e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57304.1 - 1.9e-12 47.3 1.2 3.9e-12 46.2 1.2 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57304.1 - 0.00031 21.3 0.4 0.00031 21.3 0.4 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57305.1 - 6e-16 58.4 2.2 6e-16 58.4 2.2 2.5 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM57305.1 - 1.2e-13 51.0 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57305.1 - 2.2e-07 30.5 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57305.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57305.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57306.1 - 1.7e-19 69.9 3.8 4.6e-19 68.4 2.1 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57306.1 - 1.3e-15 57.4 0.0 7.1e-15 55.0 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM57306.1 - 2.7e-07 31.1 4.3 2.9e-07 31.0 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM57306.1 - 0.0003 20.6 0.9 0.0047 16.8 0.0 2.7 2 1 1 3 3 3 1 MarR family HTH_29 PF13551.6 KFM57306.1 - 0.00094 19.2 0.3 0.019 15.0 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 KFM57306.1 - 0.0011 18.9 0.3 0.017 15.1 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM57306.1 - 0.0013 18.8 1.2 0.26 11.4 0.0 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57306.1 - 0.02 14.7 1.8 1.1 9.2 0.0 3.0 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 KFM57306.1 - 0.026 14.6 0.6 7.9 6.6 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase TrmB PF01978.19 KFM57306.1 - 0.092 12.6 0.1 12 5.9 0.0 3.0 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_17 PF12728.7 KFM57306.1 - 0.1 12.8 0.1 18 5.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain I-set PF07679.16 KFM57307.1 - 2.8e-07 30.5 0.0 4.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM57307.1 - 1.5e-06 28.3 0.1 1.6e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM57307.1 - 3.7e-06 27.1 0.1 5.2e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM57307.1 - 5.8e-06 26.8 0.0 7.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain DDE_3 PF13358.6 KFM57308.1 - 1.8e-07 31.0 0.0 2.3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57309.1 - 1.7e-16 60.2 1.0 1.7e-16 60.2 1.0 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57309.1 - 3.5e-16 59.3 0.0 1.4e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM57309.1 - 0.00012 22.6 2.8 0.00012 22.6 1.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57309.1 - 0.0033 17.5 0.3 2 8.6 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 KFM57309.1 - 0.014 15.2 2.9 2 8.3 0.0 3.1 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 KFM57309.1 - 0.024 14.7 1.1 7.2 6.8 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_Crp_2 PF13545.6 KFM57309.1 - 0.025 14.5 0.5 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_26 PF13443.6 KFM57309.1 - 0.11 12.9 0.3 3.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain PKK PF12474.8 KFM57310.1 - 9.3e-38 129.5 51.0 5.1e-37 127.1 45.7 4.0 3 1 1 4 4 4 2 Polo kinase kinase PDU_like PF15953.5 KFM57310.1 - 0.0075 16.4 1.0 0.0075 16.4 1.0 1.9 2 0 0 2 2 2 1 Putative propanediol utilisation FAM184 PF15665.5 KFM57310.1 - 0.44 10.3 60.7 1.4 8.6 44.0 4.0 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B DDE_3 PF13358.6 KFM57311.1 - 5.6e-16 58.6 0.1 6.2e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57311.1 - 8e-16 58.0 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57311.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57311.1 - 0.0022 17.7 0.1 0.12 12.2 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57311.1 - 0.016 15.3 0.1 0.067 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57311.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM57312.1 - 5.3e-16 58.6 3.5 6.1e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57312.1 - 1.4e-13 50.8 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57312.1 - 2.7e-07 30.2 1.6 7.4e-07 28.8 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57312.1 - 0.0027 17.5 0.6 0.008 15.9 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57312.1 - 0.021 15.0 1.2 0.095 12.8 0.4 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM57312.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Dynein_C PF18199.1 KFM57315.1 - 2.5e-97 325.8 0.0 3e-97 325.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KFM57315.1 - 9.4e-23 80.8 0.0 1.8e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Corona_S2 PF01601.16 KFM57315.1 - 0.14 10.6 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein HTH_Tnp_Tc3_2 PF01498.18 KFM57316.1 - 2.6e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57316.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57316.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57316.1 - 0.0023 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57316.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57317.1 - 2e-16 60.0 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57317.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease BTB_2 PF02214.22 KFM57318.1 - 1.8e-19 69.9 0.0 3.2e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFM57318.1 - 0.0012 19.1 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain MTCP1 PF08991.10 KFM57318.1 - 0.22 11.8 7.1 5.1 7.4 0.4 2.3 2 0 0 2 2 2 0 Mature-T-Cell Proliferation I type zf-H2C2_2 PF13465.6 KFM57322.1 - 6.9e-33 111.6 32.2 3.3e-09 36.8 0.2 6.1 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57322.1 - 2e-20 72.0 35.3 0.00011 22.5 0.8 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57322.1 - 2.2e-18 65.4 32.2 0.00082 20.0 0.2 6.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM57322.1 - 2.2e-10 40.6 13.9 0.0051 17.1 0.4 5.7 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM57322.1 - 2e-07 31.2 32.0 0.017 15.5 1.8 6.5 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM57322.1 - 0.0042 16.8 19.2 0.13 12.0 2.7 5.1 5 0 0 5 5 5 1 zinc-finger C2H2-type BolA PF01722.18 KFM57322.1 - 0.019 15.2 8.7 1.3 9.3 3.6 3.9 2 1 0 2 2 2 0 BolA-like protein CNRIP1 PF15043.6 KFM57322.1 - 0.083 12.4 0.1 0.37 10.3 0.1 2.1 1 1 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 DUF3268 PF11672.8 KFM57322.1 - 0.097 13.0 3.7 6.9 7.0 0.2 2.9 2 0 0 2 2 2 0 zinc-finger-containing domain GAGA PF09237.11 KFM57322.1 - 0.099 12.5 1.1 6.6 6.6 0.1 2.7 2 0 0 2 2 2 0 GAGA factor Zn-ribbon_8 PF09723.10 KFM57322.1 - 0.13 12.4 13.2 2.4 8.3 0.8 3.9 2 1 0 3 3 3 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFM57322.1 - 0.17 11.9 32.6 1.1 9.3 0.9 5.8 5 0 0 5 5 5 0 C2H2-type zinc finger DUF2180 PF09947.9 KFM57322.1 - 0.28 11.2 6.6 5.8 7.0 0.5 3.7 1 1 3 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2180) LIM PF00412.22 KFM57322.1 - 0.28 11.4 16.1 6.9 7.0 1.6 4.5 1 1 3 4 4 4 0 LIM domain zf-H2C2_5 PF13909.6 KFM57322.1 - 0.7 9.7 23.9 0.23 11.3 0.7 5.4 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 KFM57322.1 - 0.84 10.4 10.6 3.3 8.5 1.4 3.2 1 1 2 3 3 3 0 zinc-ribbon family zf-Di19 PF05605.12 KFM57322.1 - 1.7 9.0 17.2 0.67 10.3 1.7 3.6 1 1 3 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 KFM57322.1 - 6.9 6.7 12.4 2.6 8.1 1.0 3.2 2 1 1 3 3 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HTH_Tnp_Tc3_2 PF01498.18 KFM57323.1 - 5e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57323.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57323.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57323.1 - 0.0027 17.5 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57323.1 - 2.3 8.9 15.6 0.12 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Cullin_binding PF03556.15 KFM57324.1 - 3.5e-31 108.1 1.1 5.5e-31 107.5 1.1 1.3 1 0 0 1 1 1 1 Cullin binding DUF4441 PF14536.6 KFM57324.1 - 0.024 14.8 2.5 1.4 9.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) UPF0016 PF01169.19 KFM57325.1 - 1.8e-43 146.7 22.5 5.4e-22 77.9 5.8 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 KFM57325.1 - 5.3e-05 23.0 6.6 0.00066 19.5 0.0 2.7 2 0 0 2 2 2 1 Putative manganese efflux pump GDA1_CD39 PF01150.17 KFM57325.1 - 0.048 12.3 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family DUF1699 PF08004.11 KFM57325.1 - 0.08 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Pkinase_Tyr PF07714.17 KFM57327.1 - 1.5e-21 76.8 0.0 1.8e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM57327.1 - 6.7e-14 51.9 0.0 7.7e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57328.1 - 1.7e-06 27.6 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM57328.1 - 4.8e-05 22.9 0.0 5.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ELYS PF13934.6 KFM57329.1 - 1.1e-38 133.5 0.0 2.9e-38 132.0 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore complex assembly ELYS-bb PF16687.5 KFM57330.1 - 7e-64 216.2 0.8 2.4e-63 214.5 0.8 1.7 1 1 0 1 1 1 1 beta-propeller of ELYS nucleoporin DHR-2 PF06920.13 KFM57331.1 - 1.9e-205 683.5 1.5 1.9e-205 683.5 1.5 1.5 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFM57331.1 - 2e-49 168.1 0.2 3.7e-49 167.2 0.2 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFM57332.1 - 3e-37 127.5 2.4 3e-37 127.5 2.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) DHO_dh PF01180.21 KFM57333.1 - 1.2e-35 123.2 0.0 1.9e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 KFM57333.1 - 1.6e-32 111.6 0.8 1.6e-32 111.6 0.8 2.5 3 0 0 3 3 3 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 KFM57333.1 - 4e-23 81.3 12.8 4e-23 81.3 12.8 3.2 3 1 0 3 3 1 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 KFM57333.1 - 1.7e-09 37.4 0.0 4.3e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Dus PF01207.17 KFM57333.1 - 1.6e-06 27.5 0.0 9.1e-06 25.0 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Fer4_7 PF12838.7 KFM57333.1 - 1.4e-05 25.6 8.3 1.4e-05 25.6 8.3 4.3 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFM57333.1 - 3.8e-05 23.6 2.9 3.8e-05 23.6 2.9 4.5 4 1 1 5 5 5 3 4Fe-4S binding domain Fer4 PF00037.27 KFM57333.1 - 0.00011 21.9 26.3 0.00088 19.0 6.3 4.6 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_10 PF13237.6 KFM57333.1 - 0.00016 21.7 11.1 0.00016 21.7 11.1 3.5 3 1 1 4 4 4 3 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 KFM57333.1 - 0.00027 20.3 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.7 KFM57333.1 - 0.00032 20.6 2.4 0.00032 20.6 2.4 4.7 5 0 0 5 5 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 KFM57333.1 - 0.00091 19.3 11.4 0.00091 19.3 11.4 3.9 3 1 0 3 3 3 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 KFM57333.1 - 0.02 15.4 0.0 0.049 14.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_17 PF13534.6 KFM57333.1 - 0.34 11.5 24.3 0.32 11.6 1.0 4.1 4 0 0 4 4 3 0 4Fe-4S dicluster domain MutL_C PF08676.11 KFM57334.1 - 0.033 13.9 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 MutL C terminal dimerisation domain FpoO PF10621.9 KFM57335.1 - 0.094 13.0 0.1 0.67 10.3 0.0 2.3 3 0 0 3 3 3 0 F420H2 dehydrogenase subunit FpoO HATPase_c_3 PF13589.6 KFM57337.1 - 8.2e-14 51.6 0.1 9.7e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFM57337.1 - 1.2e-09 38.7 0.1 1.5e-09 38.4 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WH1 PF00568.23 KFM57338.1 - 5.9e-05 23.0 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 WH1 domain PH PF00169.29 KFM57339.1 - 3.2e-06 27.6 0.0 4.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFM57339.1 - 0.017 15.5 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain RhoGEF PF00621.20 KFM57340.1 - 2.9e-45 154.7 3.0 6.1e-45 153.7 3.0 1.6 1 0 0 1 1 1 1 RhoGEF domain Tiam_CC_Ex PF18385.1 KFM57340.1 - 4.6e-31 107.1 0.0 1.1e-30 105.9 0.0 1.7 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain RBD PF02196.15 KFM57340.1 - 2.9e-09 36.9 0.8 2.6e-08 33.8 0.0 2.9 3 0 0 3 3 3 1 Raf-like Ras-binding domain PDZ PF00595.24 KFM57340.1 - 4e-06 27.1 0.0 1.2e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFM57340.1 - 0.00019 21.2 0.0 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain TUG-UBL1 PF11470.8 KFM57340.1 - 0.00024 21.3 0.3 0.0091 16.2 0.1 3.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain PDZ_2 PF13180.6 KFM57340.1 - 0.005 17.1 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 PDZ domain FCH PF00611.23 KFM57340.1 - 0.093 13.0 2.2 7.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain SprT-like PF10263.9 KFM57343.1 - 5.7e-07 29.4 0.4 8.4e-07 28.9 0.4 1.2 1 0 0 1 1 1 1 SprT-like family SprT-like PF10263.9 KFM57344.1 - 9.8e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 SprT-like family BST2 PF16716.5 KFM57345.1 - 2.8 8.6 8.8 0.45 11.1 4.9 1.7 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 LMBR1 PF04791.16 KFM57345.1 - 4.8 6.0 6.0 4.7 6.0 6.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 KFM57345.1 - 5.4 7.1 9.9 5.7 7.0 7.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KFM57345.1 - 5.6 7.3 11.5 0.67 10.3 3.9 2.9 2 1 2 4 4 4 0 Uncharacterized conserved protein TPR_1 PF00515.28 KFM57347.1 - 1.7e-25 87.7 6.8 2.7e-06 27.0 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFM57347.1 - 8.4e-21 72.4 9.6 0.001 19.0 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFM57347.1 - 2e-18 65.5 6.9 0.00019 22.0 0.4 5.6 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFM57347.1 - 2.7e-18 66.3 3.3 0.0001 22.9 0.0 4.0 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM57347.1 - 3.3e-17 61.9 4.8 0.0011 18.6 0.0 5.6 2 2 4 6 6 6 4 TPR repeat TPR_17 PF13431.6 KFM57347.1 - 6.3e-17 60.7 3.6 0.0044 17.3 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFM57347.1 - 2.6e-16 58.4 4.6 0.0036 17.4 0.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM57347.1 - 6.2e-15 55.5 4.6 7.9e-05 23.1 0.8 3.9 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFM57347.1 - 5e-10 39.5 2.7 4.5e-05 23.7 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFM57347.1 - 1.1e-08 35.1 3.6 0.00084 19.4 0.3 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM57347.1 - 9.6e-08 31.5 0.7 0.035 14.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM57347.1 - 1.3e-06 28.7 1.9 2.5 8.9 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM57347.1 - 2.5e-05 24.4 1.0 0.046 13.9 0.1 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KFM57347.1 - 2.6e-05 24.5 1.5 0.01 16.2 0.2 4.0 1 1 2 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM57347.1 - 0.0093 15.2 0.3 2.8 7.1 0.1 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF1641 PF07849.11 KFM57347.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) MafB PF06255.13 KFM57347.1 - 0.17 11.3 0.5 0.94 8.9 0.1 2.1 2 0 0 2 2 2 0 Neisseria toxin MafB WHAMM-JMY_N PF15920.5 KFM57348.1 - 0.037 13.9 1.6 0.17 11.8 0.2 2.6 2 1 1 3 3 3 0 N-terminal of Junction-mediating and WASP homolog-associated Laminin_N PF00055.17 KFM57351.1 - 3.8e-80 268.8 0.0 3.8e-80 268.8 0.0 2.4 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFM57351.1 - 8.7e-42 141.1 96.1 6.4e-12 45.4 12.1 6.3 6 0 0 6 6 6 5 Laminin EGF domain F5_F8_type_C PF00754.25 KFM57351.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain HTH_Tnp_Tc3_2 PF01498.18 KFM57352.1 - 4.4e-16 58.9 3.5 6e-16 58.4 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57352.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57352.1 - 2.1e-07 30.6 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57352.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57352.1 - 0.03 14.5 0.4 0.095 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM57352.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Orai-1 PF07856.12 KFM57354.1 - 2.3e-07 30.7 1.2 3.4e-07 30.1 1.2 1.3 1 0 0 1 1 1 1 Mediator of CRAC channel activity ERCC3_RAD25_C PF16203.5 KFM57356.1 - 7.8e-124 411.8 3.2 1.3e-123 411.0 3.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KFM57356.1 - 1.2e-39 135.3 0.0 3.7e-39 133.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM57356.1 - 1.8e-17 63.8 0.0 5.2e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFM57356.1 - 1.4e-10 41.5 1.7 4.8e-10 39.8 0.2 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFM57356.1 - 3.8e-07 29.2 0.4 5.4e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_34 PF13872.6 KFM57356.1 - 0.0013 17.7 0.1 0.0025 16.8 0.1 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Terminase_5 PF06056.12 KFM57356.1 - 0.081 12.8 0.1 0.33 10.9 0.1 2.1 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) LCM PF04072.14 KFM57357.1 - 1.6e-20 73.8 0.0 2.1e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase MIT_C PF16565.5 KFM57357.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 1 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT Kelch_4 PF13418.6 KFM57358.1 - 6.6e-25 86.9 6.7 1.7e-07 31.2 0.0 6.3 5 1 2 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM57358.1 - 1e-22 79.6 9.1 6.1e-05 22.9 0.0 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFM57358.1 - 2.2e-21 75.3 10.4 8.4e-05 22.7 0.0 6.7 6 1 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFM57358.1 - 1e-20 73.5 1.8 4e-08 33.3 0.2 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KFM57358.1 - 2.8e-16 58.8 11.9 0.002 17.7 0.3 6.9 7 0 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 KFM57358.1 - 9.8e-08 31.7 13.3 0.65 10.1 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Glyoxal_oxid_N PF07250.11 KFM57358.1 - 2e-06 27.2 0.1 0.0042 16.3 0.0 2.4 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus RWD PF05773.22 KFM57360.1 - 1.8e-22 79.8 0.3 4e-22 78.7 0.3 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KFM57360.1 - 9.7e-14 51.3 42.1 1.4e-08 34.9 6.2 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KFM57360.1 - 2.9e-05 23.9 7.7 2.9e-05 23.9 7.7 4.3 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM57360.1 - 0.00013 21.9 4.0 0.00013 21.9 4.0 4.2 3 2 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFM57360.1 - 0.00051 20.3 4.4 0.00051 20.3 4.4 4.6 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM57360.1 - 0.0023 17.7 3.4 0.0023 17.7 3.4 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Perm-CXXC PF15629.6 KFM57360.1 - 1.3 9.3 11.1 8.5 6.7 0.1 3.7 3 0 0 3 3 3 0 Permuted single zf-CXXC unit DDE_Tnp_1_7 PF13843.6 KFM57361.1 - 0.0056 16.0 0.3 0.0074 15.6 0.3 1.2 1 0 0 1 1 1 1 Transposase IS4 Pro_isomerase PF00160.21 KFM57362.1 - 5.1e-46 156.8 0.0 6.6e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 KFM57362.1 - 2e-15 55.8 7.6 5.5e-06 26.0 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM57362.1 - 1.7e-11 43.3 6.4 2.6e-05 24.0 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM57362.1 - 5.1e-10 38.9 0.6 0.0006 19.4 0.0 3.3 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 KFM57362.1 - 3.7e-07 29.8 2.6 0.0052 16.9 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM57362.1 - 5.8e-07 29.7 0.1 4.7e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM57362.1 - 3.4e-06 27.6 0.2 6.5e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM57362.1 - 9e-06 25.8 0.9 2.3e-05 24.5 0.3 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM57362.1 - 3e-05 24.0 3.4 0.0028 17.7 0.0 3.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KFM57362.1 - 0.00046 20.8 2.3 0.41 11.6 0.6 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM57362.1 - 0.0011 19.5 0.6 1.5 9.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM57362.1 - 0.007 16.8 3.0 0.017 15.6 0.7 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM57362.1 - 0.0081 15.4 0.3 0.032 13.4 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM57362.1 - 0.011 16.1 0.0 0.066 13.6 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat MMR_HSR1_Xtn PF16897.5 KFM57362.1 - 0.018 15.1 0.3 0.032 14.3 0.3 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TPR_7 PF13176.6 KFM57362.1 - 0.095 12.8 0.5 5 7.4 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Gene66 PF02053.15 KFM57362.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Gene 66 (IR5) protein MIT PF04212.18 KFM57362.1 - 0.13 12.3 1.2 3.9 7.6 0.3 2.6 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Cadherin PF00028.17 KFM57363.1 - 2.1e-08 34.5 0.3 2.8e-08 34.1 0.3 1.2 1 0 0 1 1 1 1 Cadherin domain Pho88 PF10032.9 KFM57363.1 - 0.17 11.1 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Phosphate transport (Pho88) Cadherin PF00028.17 KFM57364.1 - 7.3e-59 196.2 10.4 1.1e-17 64.3 0.1 5.4 5 0 0 5 5 5 5 Cadherin domain Laminin_G_2 PF02210.24 KFM57364.1 - 1.6e-17 64.2 0.0 5.7e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.23 KFM57364.1 - 1.7e-13 50.9 0.0 5.3e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Laminin G domain EGF PF00008.27 KFM57364.1 - 0.0042 17.3 8.0 0.0089 16.3 8.0 1.6 1 0 0 1 1 1 1 EGF-like domain Cadherin_3 PF16184.5 KFM57364.1 - 0.0049 16.9 7.1 6.4 6.8 0.1 4.7 5 1 0 5 5 5 2 Cadherin-like DUF1080 PF06439.11 KFM57364.1 - 0.005 17.0 0.2 0.032 14.4 0.0 2.3 2 1 0 2 2 2 1 Domain of Unknown Function (DUF1080) EGF_2 PF07974.13 KFM57364.1 - 0.013 15.8 9.8 0.032 14.6 9.8 1.7 1 0 0 1 1 1 0 EGF-like domain Laminin_G_3 PF13385.6 KFM57364.1 - 0.08 13.1 0.0 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily EGF_3 PF12947.7 KFM57364.1 - 0.16 12.2 7.4 0.097 12.9 4.4 2.2 2 0 0 2 2 2 0 EGF domain EGF_CA PF07645.15 KFM57364.1 - 2.6 8.3 15.9 0.23 11.7 7.9 2.4 2 0 0 2 2 2 0 Calcium-binding EGF domain Invasin_D3 PF09134.10 KFM57364.1 - 4.2 7.7 0.0 4.2 7.7 0.0 3.7 5 1 1 6 6 5 0 Invasin, domain 3 Cadherin_C PF01049.17 KFM57365.1 - 6.9e-50 169.1 0.2 1.4e-49 168.2 0.2 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_2 PF02210.24 KFM57365.1 - 2.2e-22 79.9 0.3 3.1e-22 79.5 0.3 1.2 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 KFM57365.1 - 1.9e-11 44.0 35.0 1.6e-07 31.5 9.1 3.8 3 1 0 3 3 3 3 EGF-like domain Laminin_G_1 PF00054.23 KFM57365.1 - 5.6e-11 42.8 0.0 8.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFM57365.1 - 2.5e-05 24.7 30.9 8.6e-05 23.0 7.7 4.4 4 0 0 4 4 3 2 Human growth factor-like EGF cEGF PF12662.7 KFM57365.1 - 5.4e-05 23.0 3.7 5.4e-05 23.0 3.7 4.1 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_2 PF07974.13 KFM57365.1 - 9e-05 22.8 32.8 0.0062 16.9 9.2 3.6 2 1 1 3 3 3 2 EGF-like domain EGF_CA PF07645.15 KFM57365.1 - 0.00084 19.5 5.9 0.00084 19.5 5.9 3.6 3 0 0 3 3 3 2 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFM57365.1 - 0.023 15.0 28.7 0.24 11.7 5.1 3.6 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site Phage_holin_3_6 PF07332.11 KFM57365.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Tme5_EGF_like PF09064.10 KFM57365.1 - 1.5 8.8 13.4 0.55 10.2 1.2 3.7 4 0 0 4 4 4 0 Thrombomodulin like fifth domain, EGF-like PLAC PF08686.11 KFM57367.1 - 1.8 9.4 7.1 18 6.2 0.2 3.2 3 0 0 3 3 3 0 PLAC (protease and lacunin) domain SBP_bac_3 PF00497.20 KFM57368.1 - 0.00019 20.9 0.0 0.00023 20.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 KFM57368.1 - 0.0012 18.7 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan PF00060.26 KFM57369.1 - 4.8e-12 45.9 0.0 4.8e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan PF00060.26 KFM57370.1 - 1.9e-19 70.0 0.2 2.4e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 KFM57371.1 - 2e-24 86.4 0.0 2.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFM57371.1 - 1.5e-23 83.2 0.2 2.4e-23 82.5 0.2 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM57371.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.4 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFM57371.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein ANF_receptor PF01094.28 KFM57372.1 - 1.2e-27 97.0 0.0 1.3e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KFM57372.1 - 0.0015 18.3 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein G-patch PF01585.23 KFM57373.1 - 1.1e-14 54.1 2.4 2.3e-14 53.0 2.4 1.6 1 0 0 1 1 1 1 G-patch domain DND1_DSRM PF14709.7 KFM57373.1 - 6.5e-13 48.7 0.4 1.6e-12 47.5 0.4 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KFM57373.1 - 2.1e-11 44.4 4.4 3.4e-11 43.7 0.1 3.3 2 0 0 2 2 2 1 Double-stranded RNA binding motif G-patch_2 PF12656.7 KFM57373.1 - 7.7e-06 25.9 0.3 7.7e-06 25.9 0.3 2.9 2 0 0 2 2 2 1 G-patch domain Pkinase PF00069.25 KFM57375.1 - 3.6e-59 200.3 0.0 4.2e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57375.1 - 3.5e-34 118.3 0.0 4.2e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM57375.1 - 0.00031 19.8 0.1 0.0082 15.1 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM57375.1 - 0.003 16.9 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFM57375.1 - 0.011 15.1 0.1 0.03 13.7 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RestrictionSfiI PF11487.8 KFM57375.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI APH PF01636.23 KFM57375.1 - 0.096 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM57375.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Helicase_C PF00271.31 KFM57376.1 - 7.5e-19 68.1 0.2 5.2e-18 65.4 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM57376.1 - 3.6e-15 56.2 0.0 6.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KFM57376.1 - 7.3e-13 49.0 2.6 3.3e-12 47.0 2.6 2.2 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KFM57376.1 - 1.7e-06 28.1 0.2 2.3e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KFM57376.1 - 0.00022 20.6 0.1 0.00041 19.7 0.1 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain SmaI PF17411.2 KFM57376.1 - 0.019 14.1 0.0 0.046 12.9 0.0 1.6 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease Osmo_CC PF08946.10 KFM57376.1 - 0.084 13.1 2.4 0.25 11.6 2.4 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil OmpH PF03938.14 KFM57376.1 - 0.45 10.8 5.8 1.4 9.3 5.8 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-HIT PF04438.16 KFM57378.1 - 6.8e-08 32.2 11.7 6.8e-08 32.2 11.7 1.7 2 0 0 2 2 2 1 HIT zinc finger ELO PF01151.18 KFM57379.1 - 1.2e-53 182.2 22.1 1.5e-53 181.9 22.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family HTH_Tnp_Tc3_2 PF01498.18 KFM57382.1 - 4.2e-16 58.9 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57382.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57382.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57382.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57382.1 - 2.1 9.0 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Prp18 PF02840.15 KFM57383.1 - 6.3e-62 207.9 0.1 6.3e-62 207.9 0.1 2.1 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KFM57383.1 - 4.3e-09 35.7 7.8 4.3e-09 35.7 7.8 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Alk_phosphatase PF00245.20 KFM57384.1 - 4.4e-136 454.1 0.0 4.9e-136 454.0 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 KFM57384.1 - 0.018 14.4 0.1 0.065 12.6 0.1 2.0 1 1 0 1 1 1 0 Sulfatase BOP1NT PF08145.12 KFM57385.1 - 2.8e-109 365.0 13.6 5.2e-109 364.2 13.6 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KFM57385.1 - 6.4e-25 86.9 3.5 4.3e-08 33.7 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM57385.1 - 1.1e-07 32.0 0.2 0.0022 18.2 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM57385.1 - 0.00047 18.9 0.0 0.00077 18.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF3727 PF12527.8 KFM57385.1 - 0.48 10.7 2.5 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3727) Clathrin_bdg PF15045.6 KFM57387.1 - 1.7e-08 34.3 0.1 4.8e-08 32.9 0.1 1.9 1 1 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking DDE_3 PF13358.6 KFM57388.1 - 3.4e-13 49.6 0.0 4.5e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CUB PF00431.20 KFM57389.1 - 2.1e-23 82.8 0.1 3.6e-10 40.2 0.0 5.4 5 1 0 5 5 5 3 CUB domain stn_TNFRSF12A PF12191.8 KFM57389.1 - 0.014 15.7 0.3 0.025 14.8 0.3 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DIX PF00778.17 KFM57390.1 - 7.1e-29 99.5 0.2 1.2e-28 98.7 0.2 1.4 1 0 0 1 1 1 1 DIX domain Sec10 PF07393.11 KFM57390.1 - 0.016 13.6 0.7 0.019 13.4 0.7 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 GD_AH_C PF04295.13 KFM57390.1 - 0.033 13.0 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus DLH PF01738.18 KFM57390.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DnaJ PF00226.31 KFM57391.1 - 1.7e-21 76.1 0.9 1.7e-21 76.1 0.9 2.1 2 0 0 2 2 2 1 DnaJ domain TRAP-gamma PF07074.12 KFM57391.1 - 0.0076 15.8 0.1 0.022 14.3 0.1 1.8 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Ctr PF04145.15 KFM57391.1 - 0.011 16.3 0.4 0.047 14.3 0.3 2.1 2 1 0 2 2 2 0 Ctr copper transporter family DinB_2 PF12867.7 KFM57391.1 - 0.068 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 DinB superfamily SRP_SPB PF02978.19 KFM57391.1 - 0.085 13.5 0.0 19 5.9 0.0 2.4 2 0 0 2 2 2 0 Signal peptide binding domain LMBR1 PF04791.16 KFM57391.1 - 0.1 11.5 0.3 0.18 10.7 0.2 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein AATF-Che1 PF13339.6 KFM57391.1 - 0.96 10.1 6.5 0.29 11.8 1.2 2.5 2 2 0 2 2 2 0 Apoptosis antagonizing transcription factor PRA1 PF03208.19 KFM57392.1 - 3e-30 104.7 2.2 3.2e-30 104.6 2.2 1.0 1 0 0 1 1 1 1 PRA1 family protein ABC2_membrane_5 PF13346.6 KFM57392.1 - 0.063 12.8 12.2 0.11 12.1 12.2 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4133 PF13571.6 KFM57392.1 - 4.1 7.8 9.0 3.8 7.9 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Renin_r PF07850.14 KFM57393.1 - 5.6e-25 87.8 0.0 9e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Renin receptor-like protein TGT_C2 PF14810.6 KFM57393.1 - 0.028 14.5 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase Homeodomain PF00046.29 KFM57394.1 - 2.9e-20 71.9 2.0 5e-20 71.1 2.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM57394.1 - 1e-05 25.3 0.1 2.3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain RRM_1 PF00076.22 KFM57395.1 - 1.9e-83 274.3 11.5 5.5e-17 61.4 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM57395.1 - 1.1e-13 50.8 0.0 0.14 12.0 0.0 5.8 6 0 0 6 6 6 4 Occluded RNA-recognition motif RRM_7 PF16367.5 KFM57395.1 - 4.9e-07 29.8 1.5 1.4 9.1 0.0 5.9 6 1 0 7 7 7 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM57395.1 - 9e-05 22.4 0.8 24 5.0 0.0 5.1 6 0 0 6 6 6 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFM57395.1 - 0.038 14.0 20.3 0.14 12.2 0.0 6.5 7 2 0 7 7 7 0 RNA binding motif DUF4824 PF16106.5 KFM57395.1 - 0.14 11.4 0.0 0.14 11.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4824) Fib_alpha PF08702.10 KFM57397.1 - 0.0065 16.7 0.4 0.0076 16.4 0.4 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF5440 PF17509.2 KFM57397.1 - 0.06 13.0 0.1 5.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5440) Packaging_FI PF14000.6 KFM57397.1 - 0.07 13.6 0.4 0.07 13.6 0.4 1.9 1 1 1 2 2 2 0 DNA packaging protein FI CybS PF05328.12 KFM57399.1 - 5e-30 103.9 0.4 6e-30 103.7 0.4 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DSPc PF00782.20 KFM57401.1 - 4.5e-20 71.8 0.0 6.6e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 KFM57401.1 - 7.9e-05 23.1 0.0 0.00077 19.9 0.0 2.0 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.27 KFM57401.1 - 0.00022 20.9 0.2 0.00038 20.1 0.2 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFM57401.1 - 0.0065 16.1 0.1 0.01 15.4 0.1 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM57401.1 - 0.018 15.1 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Glycos_transf_4 PF00953.21 KFM57402.1 - 2.9e-36 124.9 18.2 2.9e-36 124.9 18.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 Pou PF00157.17 KFM57403.1 - 2.7e-21 75.3 0.1 8.3e-21 73.7 0.0 1.9 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFM57403.1 - 1.1e-18 66.8 2.6 2.1e-18 65.9 2.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM57403.1 - 0.0061 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain PRIMA1 PF16101.5 KFM57404.1 - 4.4 7.4 12.3 11 6.1 12.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-C2H2_4 PF13894.6 KFM57406.1 - 5.5e-09 36.1 5.3 1.1e-05 25.9 0.6 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM57406.1 - 4.7e-08 33.1 8.9 8.2e-05 22.8 1.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM57406.1 - 4.7e-08 33.1 2.8 8.1e-06 26.0 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFM57406.1 - 8.3e-08 32.3 0.7 8.3e-08 32.3 0.7 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KFM57406.1 - 1.3e-07 31.7 2.4 6.3e-05 23.2 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM57406.1 - 2.5e-05 24.1 2.7 5.2e-05 23.1 1.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 KFM57406.1 - 0.011 16.0 1.6 0.013 15.8 1.6 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KFM57406.1 - 0.055 13.1 0.6 0.15 11.7 0.2 1.8 1 1 1 2 2 2 0 MYST family zinc finger domain zf-C2H2_8 PF15909.5 KFM57406.1 - 0.078 13.3 0.8 0.079 13.3 0.8 1.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon cEGF PF12662.7 KFM57406.1 - 0.087 12.8 0.2 2 8.4 0.1 2.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like Arc PF03869.14 KFM57407.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Arc-like DNA binding domain DUF1325 PF07039.11 KFM57408.1 - 5.4e-06 26.5 1.3 1e-05 25.6 0.4 1.9 2 0 0 2 2 2 1 SGF29 tudor-like domain Com_YlbF PF06133.11 KFM57408.1 - 2 9.0 12.1 1.5 9.4 6.1 2.5 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Ribosomal_L36e PF01158.18 KFM57408.1 - 2.6 8.4 8.0 0.21 11.9 2.4 2.0 2 0 0 2 2 2 0 Ribosomal protein L36e RPW8 PF05659.11 KFM57409.1 - 0.0031 17.2 2.8 0.0041 16.8 2.4 1.5 1 1 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 BLOC1_2 PF10046.9 KFM57409.1 - 0.0066 16.7 5.8 0.021 15.1 4.0 2.5 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF148 PF02520.17 KFM57409.1 - 0.0079 16.3 2.7 0.014 15.5 0.3 2.2 1 1 1 2 2 2 1 Domain of unknown function DUF148 DUF1664 PF07889.12 KFM57409.1 - 0.011 15.7 5.1 0.54 10.3 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1359 PF07097.11 KFM57409.1 - 0.022 15.0 3.4 0.3 11.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) DUF3486 PF11985.8 KFM57409.1 - 0.024 15.1 0.2 0.046 14.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) ANAPC4 PF12896.7 KFM57409.1 - 0.028 13.9 0.4 0.051 13.1 0.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 XhlA PF10779.9 KFM57409.1 - 0.062 13.5 2.2 0.062 13.5 2.2 2.4 3 0 0 3 3 3 0 Haemolysin XhlA DUF1722 PF08349.11 KFM57409.1 - 0.076 13.3 1.6 0.57 10.5 0.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1722) Lge1 PF11488.8 KFM57409.1 - 0.097 12.9 0.4 0.097 12.9 0.4 2.1 2 1 0 2 2 1 0 Transcriptional regulatory protein LGE1 DUF2203 PF09969.9 KFM57409.1 - 0.1 13.3 4.2 0.22 12.3 1.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Prominin PF05478.11 KFM57409.1 - 0.1 10.6 4.5 0.11 10.4 4.5 1.0 1 0 0 1 1 1 0 Prominin PEP-utilisers_N PF05524.13 KFM57409.1 - 0.11 12.7 3.3 6 7.1 0.1 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal CCDC-167 PF15188.6 KFM57409.1 - 0.12 12.7 0.5 0.12 12.7 0.5 2.2 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 NPV_P10 PF05531.12 KFM57409.1 - 0.13 12.7 6.1 24 5.5 6.0 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Pik1 PF11522.8 KFM57409.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Baculo_PEP_C PF04513.12 KFM57409.1 - 0.16 12.0 2.9 2.8 8.0 2.9 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 KFM57409.1 - 0.17 10.5 3.9 0.19 10.3 3.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Allexi_40kDa PF05549.11 KFM57409.1 - 0.18 11.3 3.3 0.36 10.3 2.3 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein JIP_LZII PF16471.5 KFM57409.1 - 0.21 11.8 7.5 2.3 8.4 0.4 2.6 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II PLAC9 PF15205.6 KFM57409.1 - 0.23 11.9 4.3 0.34 11.3 1.2 2.6 2 1 1 3 3 3 0 Placenta-specific protein 9 PNPase PF03726.14 KFM57409.1 - 0.23 12.0 4.7 0.14 12.7 0.7 2.2 2 1 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain ISG65-75 PF11727.8 KFM57409.1 - 0.37 10.0 5.7 1.6 7.9 0.2 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein ATG16 PF08614.11 KFM57409.1 - 0.53 10.5 6.9 1.8 8.7 0.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF16 PF01519.16 KFM57409.1 - 0.8 10.2 8.0 0.24 11.9 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 MtrG PF04210.13 KFM57409.1 - 0.91 9.4 5.0 6.2 6.7 0.2 3.1 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G PCRF PF03462.18 KFM57409.1 - 0.96 9.3 6.7 0.28 11.0 2.5 1.9 1 1 1 2 2 2 0 PCRF domain HalX PF08663.10 KFM57409.1 - 1.4 9.3 6.6 2.9 8.3 0.2 3.0 3 1 0 3 3 3 0 HalX domain Ead_Ea22 PF13935.6 KFM57409.1 - 1.7 9.3 7.3 4.2 8.0 1.7 2.1 1 1 0 2 2 2 0 Ead/Ea22-like protein CLZ PF16526.5 KFM57409.1 - 2.5 8.5 6.7 1.5 9.2 1.8 2.9 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 KFM57409.1 - 5.4 7.3 10.1 35 4.7 4.1 3.2 2 2 0 2 2 2 0 ABC transporter C-terminal domain zf-C2H2 PF00096.26 KFM57410.1 - 4.1e-19 67.9 34.4 2.9e-06 27.4 1.5 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM57410.1 - 1.8e-15 56.5 32.0 5.5e-08 32.9 2.3 6.2 7 0 0 7 7 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM57410.1 - 6.7e-14 51.4 31.3 0.00088 19.9 2.0 5.3 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM57410.1 - 1.7e-05 24.5 13.5 1.9e-05 24.3 1.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM57410.1 - 3.4e-05 23.6 2.5 0.04 13.8 0.0 3.1 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KFM57410.1 - 0.0001 22.5 14.4 0.0036 17.6 2.2 3.3 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KFM57410.1 - 0.00033 20.2 7.9 0.086 12.5 0.0 3.8 2 1 1 3 3 3 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 KFM57410.1 - 0.0025 18.5 1.9 0.0058 17.3 1.9 1.6 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KFM57410.1 - 0.0033 17.8 7.0 0.6 10.6 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM57410.1 - 0.027 14.5 27.1 0.082 12.9 0.2 4.5 5 0 0 5 5 4 0 C2H2-type zinc finger zf_UBZ PF18439.1 KFM57410.1 - 0.039 13.6 9.4 0.42 10.2 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_7 PF15269.6 KFM57410.1 - 0.069 13.2 1.6 0.16 12.1 0.8 2.1 1 1 0 1 1 1 0 Zinc-finger DUF2225 PF09986.9 KFM57410.1 - 0.074 12.8 6.3 0.26 11.0 4.6 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.8 KFM57410.1 - 0.094 13.0 2.5 0.81 10.0 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 KFM57410.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.6 5 0 0 5 5 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 KFM57410.1 - 0.19 11.6 9.7 0.23 11.3 0.1 4.6 6 0 0 6 6 5 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 KFM57410.1 - 0.22 11.6 8.6 2.1 8.5 0.5 3.7 3 0 0 3 3 3 0 BED zinc finger Zn_ribbon_SprT PF17283.2 KFM57410.1 - 0.35 10.8 12.0 21 5.1 3.0 4.6 3 1 2 5 5 5 0 SprT-like zinc ribbon domain Zf_RING PF16744.5 KFM57410.1 - 0.66 10.1 7.9 6 7.1 0.5 3.0 1 1 2 3 3 3 0 KIAA1045 RING finger zinc_ribbon_15 PF17032.5 KFM57410.1 - 0.91 10.3 10.1 5.1 7.9 1.1 2.9 2 1 0 3 3 3 0 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM57410.1 - 1.9 8.9 15.0 1.8 8.9 0.2 3.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFM57410.1 - 3.9 7.7 15.9 0.45 10.7 4.2 3.6 4 0 0 4 4 3 0 Zinc ribbon domain Rpr2 PF04032.16 KFM57410.1 - 8.2 6.8 10.4 7.1e+02 0.6 10.7 2.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TauD PF02668.16 KFM57411.1 - 5.2e-33 115.0 0.0 7.7e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFM57411.1 - 3.4e-14 53.2 0.1 8.7e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KFM57411.1 - 0.00075 18.7 0.0 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 CsiD Acyl_transf_1 PF00698.21 KFM57412.1 - 2.9e-21 76.3 0.1 5e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain LpqV PF17301.2 KFM57412.1 - 0.088 13.1 0.7 0.81 10.0 0.1 2.3 2 0 0 2 2 2 0 Putative lipoprotein LpqV CP12 PF02672.15 KFM57412.1 - 0.23 12.2 0.4 0.23 12.2 0.4 2.0 2 0 0 2 2 2 0 CP12 domain HTH_Tnp_Tc3_2 PF01498.18 KFM57413.1 - 6.4e-10 39.2 1.5 1.3e-09 38.2 1.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57413.1 - 3.7e-06 26.8 0.1 0.00076 19.3 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_32 PF13565.6 KFM57413.1 - 0.019 15.5 2.6 0.096 13.3 0.3 2.5 2 0 0 2 2 2 0 Homeodomain-like domain CUB PF00431.20 KFM57414.1 - 4.8e-43 146.0 13.5 9e-16 58.2 0.0 4.0 4 0 0 4 4 4 3 CUB domain IN_DBD_C PF00552.21 KFM57415.1 - 0.12 11.6 3.0 3.6 7.0 0.9 2.9 2 1 1 3 3 3 0 Integrase DNA binding domain CUE PF02845.16 KFM57416.1 - 2.4e-08 33.5 0.3 0.42 10.4 0.0 4.0 4 0 0 4 4 4 3 CUE domain Dscam_C PF12355.8 KFM57416.1 - 0.055 14.4 11.2 0.17 12.9 3.4 2.5 3 0 0 3 3 3 0 Down syndrome cell adhesion molecule C terminal Thioredoxin_13 PF18401.1 KFM57416.1 - 0.084 12.8 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain DUF1296 PF06972.11 KFM57416.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) UBA PF00627.31 KFM57416.1 - 0.36 10.8 5.8 4.4 7.3 0.0 3.5 3 1 1 4 4 4 0 UBA/TS-N domain NPR3 PF03666.13 KFM57417.1 - 0.047 12.5 9.2 0.057 12.2 9.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.10 KFM57417.1 - 0.17 12.2 18.6 0.22 11.8 18.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 KFM57417.1 - 0.18 11.0 3.9 0.2 10.9 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KFM57417.1 - 1.6 7.4 13.5 1.7 7.3 13.5 1.1 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 KFM57417.1 - 3.1 6.6 9.9 3.9 6.3 9.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Neur_chan_memb PF02932.16 KFM57417.1 - 4.9 7.1 6.6 6.1 6.8 6.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop53 PF07767.11 KFM57417.1 - 7.4 5.8 34.8 9 5.6 34.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Hid1 PF12722.7 KFM57417.1 - 8.4 4.4 12.7 9.8 4.2 12.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sushi PF00084.20 KFM57418.1 - 5.5e-28 97.3 19.2 1.8e-11 44.5 0.5 4.0 4 0 0 4 4 4 3 Sushi repeat (SCR repeat) HRM PF02793.22 KFM57418.1 - 1.6e-06 28.3 9.8 0.0032 17.7 0.7 3.3 2 1 1 3 3 3 3 Hormone receptor domain cEGF PF12662.7 KFM57418.1 - 0.023 14.6 13.2 0.26 11.3 0.5 4.3 4 0 0 4 4 4 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFM57418.1 - 0.57 10.5 5.2 14 6.1 0.2 3.3 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site Sushi PF00084.20 KFM57419.1 - 2e-120 393.4 109.3 2.7e-13 50.3 0.5 15.8 16 0 0 16 16 15 13 Sushi repeat (SCR repeat) EGF PF00008.27 KFM57419.1 - 1.3e-39 134.0 74.1 1.2e-09 38.3 9.4 9.8 7 0 0 7 7 7 6 EGF-like domain Pentaxin PF00354.17 KFM57419.1 - 1.2e-31 109.9 0.0 2.4e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Pentaxin family Ephrin_rec_like PF07699.13 KFM57419.1 - 2.8e-27 94.2 34.2 1.6e-12 47.0 6.1 6.0 5 1 1 6 6 5 3 Putative ephrin-receptor like HYR PF02494.16 KFM57419.1 - 2e-26 92.1 3.5 1e-12 48.2 0.3 3.6 3 0 0 3 3 3 2 HYR domain hEGF PF12661.7 KFM57419.1 - 6.8e-22 77.3 88.7 2.4e-06 28.0 3.9 12.5 13 0 0 13 13 12 6 Human growth factor-like EGF Laminin_G_3 PF13385.6 KFM57419.1 - 5.7e-10 39.5 0.2 9.7e-10 38.8 0.2 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.15 KFM57419.1 - 0.00015 21.9 15.7 0.00039 20.6 3.5 14.1 17 1 1 18 18 18 6 Calcium-binding EGF domain Laminin_G_2 PF02210.24 KFM57419.1 - 0.053 14.1 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain EGF_3 PF12947.7 KFM57419.1 - 0.27 11.5 97.7 0.034 14.3 2.0 11.8 12 0 0 12 12 12 0 EGF domain EGF_2 PF07974.13 KFM57419.1 - 2 8.8 89.3 0.52 10.7 10.7 9.3 9 0 0 9 9 8 0 EGF-like domain TNFR_c6 PF00020.18 KFM57419.1 - 7.2 7.1 31.8 1.6 9.2 1.3 8.1 4 2 1 5 5 5 0 TNFR/NGFR cysteine-rich region E2F_TDP PF02319.20 KFM57420.1 - 1.9e-17 63.1 0.0 5e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain ThiF PF00899.21 KFM57421.1 - 7.9e-17 61.4 0.0 1.1e-13 51.2 0.0 2.2 2 0 0 2 2 2 2 ThiF family DUF3328 PF11807.8 KFM57421.1 - 0.024 14.4 0.2 0.16 11.7 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) Frag1 PF10277.9 KFM57422.1 - 2.6e-14 53.3 10.4 2.9e-14 53.1 10.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Histone PF00125.24 KFM57423.1 - 3.3e-24 85.7 1.0 3.9e-24 85.5 1.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM57423.1 - 5.6e-06 26.5 0.1 5.6e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFM57423.1 - 0.001 19.5 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFM57423.1 - 0.0053 16.8 0.8 0.0068 16.5 0.8 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 KFM57423.1 - 0.084 12.5 0.9 6.6 6.4 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Ribosomal_L23eN PF03939.13 KFM57423.1 - 0.8 10.0 12.1 0.16 12.2 5.9 2.4 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain Linker_histone PF00538.19 KFM57424.1 - 3.1e-28 97.9 0.9 7.5e-28 96.7 0.9 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family UBA PF00627.31 KFM57425.1 - 0.087 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 UBA/TS-N domain DUF5641 PF18701.1 KFM57426.1 - 1.2e-15 57.4 0.2 4e-15 55.7 0.1 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5641) Peptidase_A17 PF05380.13 KFM57426.1 - 1.2e-11 44.9 0.1 2.2e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 KFM57426.1 - 0.0018 17.9 0.0 0.0041 16.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM57426.1 - 0.051 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain rve_3 PF13683.6 KFM57426.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain S8_pro-domain PF16470.5 KFM57430.1 - 0.018 15.8 0.0 0.024 15.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase S8 pro-domain UL42 PF17638.2 KFM57430.1 - 0.13 12.2 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 HCMV UL42 Laminin_EGF PF00053.24 KFM57431.1 - 4.9e-158 513.2 427.2 4.5e-10 39.5 15.4 23.2 22 1 1 23 23 23 22 Laminin EGF domain Laminin_G_2 PF02210.24 KFM57431.1 - 1.8e-118 390.5 2.6 5.1e-27 95.0 0.0 5.6 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 KFM57431.1 - 1.2e-115 381.4 0.8 7e-26 91.0 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_N PF00055.17 KFM57431.1 - 8.5e-76 254.6 0.0 8.5e-76 254.6 0.0 3.1 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 KFM57431.1 - 5.4e-31 107.3 0.0 1.4e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_G_3 PF13385.6 KFM57431.1 - 2.6e-12 47.1 0.6 0.0051 17.0 0.1 5.3 5 0 0 5 5 5 3 Concanavalin A-like lectin/glucanases superfamily Laminin_II PF06009.12 KFM57431.1 - 2.8e-10 40.4 6.7 2.8e-10 40.4 6.7 4.2 3 1 1 5 5 5 1 Laminin Domain II Laminin_I PF06008.14 KFM57431.1 - 3.5e-09 36.8 5.8 3.5e-09 36.8 5.8 3.1 1 1 2 3 3 3 1 Laminin Domain I DUF1664 PF07889.12 KFM57431.1 - 5.9 6.9 7.2 20 5.3 0.4 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) HTH_Tnp_Tc3_2 PF01498.18 KFM57432.1 - 8.6e-15 54.7 0.5 1.7e-14 53.8 0.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57432.1 - 3.8e-10 39.7 0.0 6.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57432.1 - 0.00014 21.5 0.3 0.00031 20.4 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_50 PF18024.1 KFM57432.1 - 0.076 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM57432.1 - 0.083 12.7 0.7 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM57432.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase HTH_32 PF13565.6 KFM57432.1 - 0.24 12.0 11.7 0.67 10.6 2.4 3.2 2 1 1 3 3 3 0 Homeodomain-like domain V-set PF07686.17 KFM57433.1 - 0.0027 17.8 0.0 0.0031 17.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM57433.1 - 0.05 14.2 0.0 0.062 13.9 0.0 1.3 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFM57433.1 - 0.095 12.8 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 Immunoglobulin I-set domain TRSP PF12500.8 KFM57433.1 - 0.13 12.1 0.0 0.62 10.0 0.0 1.8 1 1 1 2 2 2 0 TRSP domain C terminus to PRTase_2 Ig_4 PF16680.5 KFM57433.1 - 0.16 12.3 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFM57434.1 - 3.3e-11 43.1 0.4 1.3e-10 41.2 0.1 2.1 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM57434.1 - 2.6e-09 37.6 0.2 1.6e-05 25.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM57434.1 - 2.7e-09 37.2 0.1 5.1e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM57434.1 - 9.3e-09 35.3 0.3 5.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM57434.1 - 4.3e-06 26.7 0.0 0.0044 17.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Lep_receptor_Ig PF06328.11 KFM57434.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Ig-like C2-type domain Ig_C17orf99 PF17736.1 KFM57434.1 - 0.066 13.3 0.2 5.1 7.2 0.0 2.4 2 1 0 2 2 2 0 C17orf99 Ig domain BiPBP_C PF06832.12 KFM57434.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Otopetrin PF03189.13 KFM57438.1 - 6.9e-75 252.5 11.8 7.9e-75 252.4 11.8 1.0 1 0 0 1 1 1 1 Otopetrin L6_membrane PF05805.12 KFM57438.1 - 3.4 7.2 9.1 1.2 8.7 5.8 1.9 2 0 0 2 2 2 0 L6 membrane protein HLH PF00010.26 KFM57440.1 - 1.4e-17 63.4 0.3 2.1e-17 62.8 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFM57440.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sushi PF00084.20 KFM57441.1 - 1.3e-42 144.2 14.1 1.5e-09 38.3 0.3 5.2 5 0 0 5 5 5 5 Sushi repeat (SCR repeat) HRM PF02793.22 KFM57441.1 - 8.5e-05 22.8 10.8 0.49 10.7 0.2 4.8 3 1 1 4 4 4 2 Hormone receptor domain DNA_pol_E_B PF04042.16 KFM57441.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B DDE_3 PF13358.6 KFM57442.1 - 1.6e-14 53.9 0.0 2.2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pep_M12B_propep PF01562.19 KFM57443.1 - 0.00029 21.1 0.0 0.00029 21.1 0.0 1.0 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 KFM57444.1 - 6.8e-21 74.6 6.9 6.8e-21 74.6 6.9 1.8 2 0 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin PF01421.19 KFM57444.1 - 1.7e-11 44.4 0.1 2.6e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 KFM57444.1 - 0.00028 20.6 0.2 0.00038 20.1 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM57444.1 - 0.00048 20.3 0.7 0.00061 20.0 0.7 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KFM57444.1 - 0.002 18.0 0.4 0.0029 17.4 0.4 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 KFM57444.1 - 0.0037 17.8 0.1 0.0053 17.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFM57444.1 - 0.0069 16.3 0.3 0.0097 15.8 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KFM57444.1 - 0.0097 14.9 0.1 0.012 14.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase M66 DUF4953 PF16313.5 KFM57444.1 - 0.046 12.9 0.1 0.069 12.3 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Astacin PF01400.24 KFM57444.1 - 0.074 12.7 0.3 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M78 PF06114.13 KFM57444.1 - 0.075 13.0 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 IrrE N-terminal-like domain Peptidase_M7 PF02031.16 KFM57444.1 - 0.098 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Metallopep PF12044.8 KFM57444.1 - 0.19 10.3 1.0 0.25 9.9 1.0 1.1 1 0 0 1 1 1 0 Putative peptidase family UPF0506 PF11703.8 KFM57444.1 - 2.8 8.4 8.4 2 8.9 5.9 2.1 2 0 0 2 2 2 0 UPF0506 TSP_1 PF00090.19 KFM57446.1 - 2.6e-50 168.4 148.2 5e-07 29.8 5.9 12.7 12 0 0 12 12 12 12 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFM57446.1 - 7.5e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Copper-fist PF00649.18 KFM57447.1 - 0.062 12.8 4.4 2.1 7.9 0.6 2.5 2 0 0 2 2 2 0 Copper fist DNA binding domain WW PF00397.26 KFM57448.1 - 2.4e-09 37.1 0.1 4.8e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 WW domain DDE_1 PF03184.19 KFM57450.1 - 2.6e-32 111.9 0.1 5.1e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Pyridoxal_deC PF00282.19 KFM57450.1 - 0.0094 14.7 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain cwf18 PF08315.12 KFM57452.1 - 0.0078 16.9 1.1 0.0085 16.8 1.1 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DnaJ PF00226.31 KFM57454.1 - 9.7e-27 92.9 5.7 1.4e-26 92.4 5.7 1.2 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 KFM57455.1 - 2.6e-78 258.6 0.2 2.6e-23 81.9 0.2 6.0 6 0 0 6 6 6 5 Thioredoxin OST3_OST6 PF04756.13 KFM57455.1 - 1.7e-15 57.2 1.3 2.1e-05 24.1 0.0 4.6 3 1 2 5 5 5 4 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFM57455.1 - 6.7e-15 55.5 1.7 0.0011 19.3 0.2 6.4 6 2 0 6 6 6 3 Thioredoxin-like domain Thioredoxin_6 PF13848.6 KFM57455.1 - 9.7e-13 48.4 0.2 0.0017 18.3 0.0 3.8 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM57455.1 - 2.4e-12 47.0 2.5 0.1 12.9 0.0 5.9 4 2 1 5 5 5 4 Thioredoxin-like Thioredoxin_7 PF13899.6 KFM57455.1 - 1.5e-07 31.5 1.7 0.0062 16.7 0.1 3.7 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KFM57455.1 - 4.9e-06 26.3 1.7 0.4 10.5 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin AhpC-TSA PF00578.21 KFM57455.1 - 5.6e-06 26.3 3.0 0.055 13.4 0.1 3.5 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_3 PF13192.6 KFM57455.1 - 6.5e-05 22.9 0.2 0.048 13.7 0.1 3.6 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_5 PF13743.6 KFM57455.1 - 7.6e-05 22.5 2.7 2.3 7.8 0.0 5.9 5 2 2 7 7 7 1 Thioredoxin Redoxin PF08534.10 KFM57455.1 - 0.00051 19.8 1.8 2.7 7.7 0.0 3.4 3 0 0 3 3 3 1 Redoxin Thioredoxin_4 PF13462.6 KFM57455.1 - 0.079 13.1 2.7 3.4 7.8 0.2 4.0 5 0 0 5 5 5 0 Thioredoxin TIMELESS PF04821.14 KFM57456.1 - 1.8e-07 30.7 0.2 2.1e-07 30.5 0.2 1.1 1 0 0 1 1 1 1 Timeless protein Methyltransf_32 PF13679.6 KFM57456.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3515 PF12028.8 KFM57457.1 - 0.24 11.1 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) CAAP1 PF15335.6 KFM57459.1 - 0.012 16.2 1.0 1.1 9.9 0.0 3.3 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Peptidase_M8 PF01457.16 KFM57462.1 - 1.6e-40 139.3 0.3 2e-40 139.0 0.3 1.0 1 0 0 1 1 1 1 Leishmanolysin cNMP_binding PF00027.29 KFM57464.1 - 2.8e-06 27.3 0.0 5.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Mycobact_memb PF05423.13 KFM57464.1 - 0.043 13.7 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Mycobacterium membrane protein Prefoldin PF02996.17 KFM57464.1 - 0.1 12.5 0.5 0.19 11.6 0.5 1.4 1 0 0 1 1 1 0 Prefoldin subunit MbeD_MobD PF04899.12 KFM57464.1 - 4.1 7.6 5.3 3 8.0 0.1 2.8 3 0 0 3 3 3 0 MbeD/MobD like Microtub_bd PF16796.5 KFM57465.1 - 0.0074 16.2 0.1 0.008 16.1 0.1 1.0 1 0 0 1 1 1 1 Microtubule binding Keratin PF02422.16 KFM57465.1 - 0.051 13.3 0.1 0.066 12.9 0.1 1.2 1 0 0 1 1 1 0 Keratin Kinesin PF00225.23 KFM57466.1 - 0.056 12.4 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain Kinesin PF00225.23 KFM57467.1 - 1.2e-58 198.6 0.1 1.2e-58 198.6 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 KFM57467.1 - 5.5e-25 87.5 0.5 5.5e-25 87.5 0.5 2.6 2 1 0 2 2 2 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Cnn_1N PF07989.11 KFM57467.1 - 0.16 12.1 14.3 0.24 11.6 3.7 3.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DNA_gyraseB PF00204.25 KFM57467.1 - 0.17 11.3 4.6 0.48 9.9 4.6 1.8 1 0 0 1 1 1 0 DNA gyrase B Exonuc_VII_L PF02601.15 KFM57467.1 - 4.8 6.7 12.8 10 5.6 12.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KFM57467.1 - 7.7 5.3 6.8 10 4.9 6.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PIF1 PF05970.14 KFM57469.1 - 1.5e-36 126.4 0.2 1.9e-36 126.0 0.2 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFM57469.1 - 2.8e-05 23.9 0.0 3.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain Acyl-CoA_dh_N PF02771.16 KFM57470.1 - 1.6e-26 93.2 0.0 2.5e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM57470.1 - 5.6e-13 48.9 0.0 3e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Imm6 PF14434.6 KFM57470.1 - 0.014 15.4 0.1 0.028 14.3 0.0 1.5 2 0 0 2 2 2 0 Immunity protein Imm6 Amidohydro_2 PF04909.14 KFM57470.1 - 0.096 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase PCI PF01399.27 KFM57471.1 - 8.7e-11 42.3 0.1 8.7e-11 42.3 0.1 3.8 4 0 0 4 4 4 1 PCI domain HTH_28 PF13518.6 KFM57472.1 - 1.3e-06 28.5 0.1 2e-06 27.8 0.1 1.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57472.1 - 0.00092 18.9 0.1 0.001 18.8 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KFM57472.1 - 0.0016 17.8 0.1 0.0026 17.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 KFM57472.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KFM57472.1 - 0.089 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KFM57472.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM57473.1 - 7.7e-12 45.3 4.0 2.6e-11 43.6 4.0 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57473.1 - 4.8e-10 39.4 0.0 1.5e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_IclR PF09339.10 KFM57473.1 - 0.00063 19.5 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KFM57473.1 - 0.11 12.4 3.9 0.17 11.8 0.5 2.9 3 0 0 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM57474.1 - 1.5e-14 53.9 0.0 2.8e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57474.1 - 1.1e-13 51.2 0.2 2.3e-13 50.2 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57474.1 - 0.00012 22.6 8.7 0.00018 22.1 1.5 2.9 3 0 0 3 3 3 1 Homeodomain-like domain PAX PF00292.18 KFM57474.1 - 0.047 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 'Paired box' domain DDE_3 PF13358.6 KFM57475.1 - 4.9e-16 58.8 0.1 5.7e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57475.1 - 7.4e-16 58.2 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57475.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57475.1 - 0.002 17.9 0.4 0.12 12.2 0.0 3.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57475.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57475.1 - 0.031 14.3 2.6 0.035 14.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM57476.1 - 1.8e-16 60.2 2.2 3.7e-16 59.1 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57476.1 - 7.3e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57477.1 - 2.1e-16 59.9 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57477.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57478.1 - 1.9e-16 60.0 2.2 4.2e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57478.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57479.1 - 2.1e-10 40.7 1.3 4.1e-10 39.8 1.3 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57479.1 - 5.7e-10 39.1 0.0 1.1e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57479.1 - 0.014 15.1 0.5 0.034 13.9 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain EF-hand_13 PF17958.1 KFM57479.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain HTH_Tnp_Tc3_2 PF01498.18 KFM57480.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57480.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57480.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57480.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57480.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Topoisom_I_N PF02919.15 KFM57481.1 - 4.4e-100 333.6 5.0 4.4e-100 333.6 5.0 3.9 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KFM57481.1 - 6.5e-100 333.2 6.9 2.1e-99 331.5 6.9 1.9 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core PPR_3 PF13812.6 KFM57484.1 - 5.7e-18 64.8 0.0 3.6e-09 36.5 0.0 3.0 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 KFM57484.1 - 9.9e-13 48.1 2.0 0.0091 16.2 0.0 4.0 2 2 2 4 4 4 3 PPR repeat family PPR_long PF17177.4 KFM57484.1 - 2.4e-10 40.2 0.0 3.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFM57484.1 - 1.7e-06 27.9 4.9 0.0061 16.7 0.1 4.3 4 0 0 4 4 4 2 PPR repeat ECSIT PF06239.11 KFM57484.1 - 0.058 12.5 0.1 2.8 7.0 0.0 2.8 1 1 1 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF4031 PF13223.6 KFM57484.1 - 0.07 13.3 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) Homeodomain PF00046.29 KFM57486.1 - 2e-07 30.8 4.4 4.5e-07 29.6 4.4 1.6 1 0 0 1 1 1 1 Homeodomain PCO_ADO PF07847.12 KFM57487.1 - 2e-48 164.5 0.0 2.5e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 KFM57487.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I RecG_N PF17190.4 KFM57487.1 - 0.16 12.7 0.1 0.25 12.1 0.1 1.3 1 0 0 1 1 1 0 RecG N-terminal helical domain Ras PF00071.22 KFM57488.1 - 6.8e-05 22.5 0.0 9.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Ras PF00071.22 KFM57489.1 - 1.6e-17 63.6 0.0 1.7e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM57489.1 - 2.9e-17 63.0 0.0 3.3e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM57489.1 - 3.6e-07 29.8 0.1 4e-07 29.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM57489.1 - 0.0046 16.3 0.1 0.0072 15.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KFM57489.1 - 0.066 13.0 0.0 0.082 12.7 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFM57489.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KFM57489.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RRM_1 PF00076.22 KFM57490.1 - 4e-09 36.2 0.0 9.3e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1338 PF07063.13 KFM57490.1 - 0.0083 15.3 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) DUF4651 PF15513.6 KFM57490.1 - 0.049 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) Nup35_RRM_2 PF14605.6 KFM57490.1 - 0.059 13.4 0.1 0.19 11.8 0.1 1.8 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TbpB_B_D PF01298.18 KFM57490.1 - 0.67 10.3 6.5 0.53 10.7 4.0 1.8 1 1 1 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Y_phosphatase PF00102.27 KFM57491.1 - 2e-23 83.2 0.0 2.1e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM57491.1 - 0.00099 18.9 0.4 0.0016 18.2 0.4 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM57491.1 - 0.0035 17.4 0.3 0.02 14.9 0.1 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM57491.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFM57492.1 - 3.8e-34 118.3 0.7 5.8e-34 117.7 0.1 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 KFM57492.1 - 1.9e-27 95.9 0.0 3.3e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM57492.1 - 6.4e-08 32.8 0.1 2.2e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Dabb PF07876.12 KFM57492.1 - 0.13 12.9 0.2 0.4 11.3 0.0 1.8 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain DDE_3 PF13358.6 KFM57493.1 - 4.9e-16 58.8 0.1 5.7e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57493.1 - 7.8e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57493.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57493.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57493.1 - 0.016 15.4 0.1 0.064 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57493.1 - 0.035 14.1 0.4 0.035 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix ThiF PF00899.21 KFM57494.1 - 4.3e-57 193.3 0.1 5.7e-57 192.9 0.1 1.1 1 0 0 1 1 1 1 ThiF family AlaDh_PNT_C PF01262.21 KFM57494.1 - 0.0038 16.6 0.1 0.0061 15.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFM57494.1 - 0.0049 16.9 0.6 0.031 14.3 0.1 2.2 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KFM57494.1 - 0.022 14.0 0.6 0.031 13.5 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KFM57494.1 - 0.039 13.5 1.8 0.073 12.6 0.6 1.9 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KFM57494.1 - 0.07 12.8 1.2 0.15 11.7 0.7 1.8 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KFM57494.1 - 0.12 13.0 0.2 0.3 11.7 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM57494.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFM57494.1 - 0.14 11.8 2.2 0.2 11.2 2.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase PKcGMP_CC PF16808.5 KFM57494.1 - 1.5 8.7 9.7 0.32 10.9 5.8 1.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PAP_assoc PF03828.19 KFM57495.1 - 7.5e-18 64.5 0.1 1.7e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFM57495.1 - 3.7e-05 23.9 0.0 8.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP1 PF08601.10 KFM57495.1 - 0.05 13.3 2.1 0.074 12.8 2.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF3570 PF12094.8 KFM57495.1 - 0.079 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) ARF7EP_C PF14949.6 KFM57496.1 - 2.1e-21 76.5 20.0 4.8e-21 75.3 20.0 1.6 1 1 0 1 1 1 1 ARF7 effector protein C-terminus RasGEF PF00617.19 KFM57498.1 - 4.4e-43 147.5 0.0 8.6e-43 146.6 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain C1_1 PF00130.22 KFM57498.1 - 6.5e-14 51.6 7.2 1.2e-13 50.7 7.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 KFM57498.1 - 7.2e-06 25.2 9.4 0.035 13.7 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFM57498.1 - 7.6e-06 25.4 5.1 0.015 15.2 0.2 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFM57498.1 - 9.4e-05 22.8 2.7 0.59 10.6 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM57498.1 - 0.0021 17.5 0.2 0.0021 17.5 0.2 3.1 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFM57498.1 - 0.42 10.5 6.7 0.3 10.9 0.2 2.9 3 0 0 3 3 3 0 EF-hand domain pair DUF2236 PF09995.9 KFM57499.1 - 3e-22 79.9 0.0 4.9e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF4706 PF15797.5 KFM57500.1 - 8.8e-30 103.4 0.2 8.8e-30 103.4 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4706) Cas6_N PF17952.1 KFM57500.1 - 0.0062 16.8 0.5 21 5.5 0.2 3.2 3 0 0 3 3 3 2 Cas6 N-terminal domain Dsh_C PF12316.8 KFM57500.1 - 0.35 11.2 4.6 0.69 10.3 4.6 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TnpV PF14198.6 KFM57500.1 - 1.3 9.0 6.5 1.5 8.8 0.1 2.8 3 0 0 3 3 3 0 Transposon-encoded protein TnpV Treslin_N PF15292.6 KFM57501.1 - 1.4e-14 53.5 36.0 2.6e-09 36.0 29.7 3.5 3 2 0 3 3 3 2 Treslin N-terminus MAM PF00629.23 KFM57502.1 - 3.9e-05 23.6 0.0 4.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KFM57503.1 - 1.1e-28 100.2 0.0 6.2e-26 91.2 0.0 2.1 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu Sema PF01403.19 KFM57505.1 - 1.5e-12 47.1 0.0 1.8e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Sema domain IFRD PF05004.13 KFM57506.1 - 5.6e-90 301.6 2.6 7.6e-90 301.1 2.6 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 KFM57506.1 - 2.3e-16 60.1 7.1 2.3e-16 60.1 0.2 2.6 2 0 0 2 2 2 1 Interferon-related protein conserved region Tn7_Tnp_TnsA_C PF08721.11 KFM57506.1 - 0.019 15.6 0.2 0.14 12.8 0.0 2.5 2 0 0 2 2 2 0 TnsA endonuclease C terminal HEAT PF02985.22 KFM57506.1 - 0.23 11.8 1.1 6.3 7.3 0.7 3.1 2 1 0 2 2 2 0 HEAT repeat HEXIM PF15313.6 KFM57507.1 - 7.1e-10 39.2 0.1 7.1e-10 39.2 0.1 3.8 3 1 0 3 3 3 1 Hexamethylene bis-acetamide-inducible protein THAP PF05485.12 KFM57510.1 - 3.1e-15 56.9 1.1 9.1e-15 55.4 1.1 1.9 1 0 0 1 1 1 1 THAP domain PHD PF00628.29 KFM57510.1 - 0.00041 20.2 17.4 0.0011 18.8 17.4 1.8 1 0 0 1 1 1 1 PHD-finger PWWP PF00855.17 KFM57511.1 - 3.7e-08 33.7 1.3 2.3e-07 31.1 1.3 2.4 1 1 0 1 1 1 1 PWWP domain ISK_Channel PF02060.15 KFM57512.1 - 0.032 13.9 0.5 0.035 13.8 0.4 1.2 1 1 0 1 1 1 0 Slow voltage-gated potassium channel DUF4244 PF14029.6 KFM57512.1 - 0.059 12.8 0.1 0.086 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) CcmD PF04995.14 KFM57512.1 - 0.063 13.4 0.4 0.063 13.4 0.4 2.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Gram_pos_anchor PF00746.21 KFM57512.1 - 0.092 12.7 1.6 0.15 12.0 1.6 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Phage_tail_APC PF16778.5 KFM57513.1 - 8 6.4 8.1 5.7 6.9 0.5 2.2 1 1 1 2 2 2 0 Phage tail assembly chaperone protein TPR_1 PF00515.28 KFM57514.1 - 6.3e-08 32.1 8.8 0.00063 19.4 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM57514.1 - 1.6e-06 27.7 4.0 0.00071 19.5 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM57514.1 - 0.00018 21.7 3.5 0.0004 20.6 3.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 LRRFIP PF09738.9 KFM57514.1 - 0.00081 19.0 4.2 0.082 12.4 0.6 2.3 2 0 0 2 2 2 2 LRRFIP family TPR_17 PF13431.6 KFM57514.1 - 0.047 14.1 0.5 0.18 12.2 0.5 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 KFM57515.1 - 2.5e-05 24.1 3.4 2.5e-05 24.1 3.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM57515.1 - 0.00028 20.7 1.5 0.00028 20.7 1.5 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM57515.1 - 0.00029 20.7 6.2 0.00067 19.6 6.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM57515.1 - 0.0011 18.7 2.7 0.0011 18.7 2.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM57515.1 - 0.013 15.3 3.0 0.013 15.3 3.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFM57515.1 - 0.017 15.4 2.7 0.026 14.8 2.7 1.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFM57515.1 - 0.02 15.2 5.7 0.05 13.9 5.7 1.8 1 1 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KFM57515.1 - 0.048 13.7 6.5 0.16 12.0 6.5 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM57515.1 - 0.14 12.4 6.9 0.25 11.5 5.5 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Sina PF03145.16 KFM57516.1 - 1.4e-07 31.7 5.7 6.6e-07 29.5 1.7 2.2 1 1 1 2 2 2 1 Seven in absentia protein family zf-TRAF PF02176.18 KFM57516.1 - 3.8e-07 30.7 9.2 7.5e-07 29.7 9.2 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger NPV_P10 PF05531.12 KFM57516.1 - 0.00018 21.9 1.7 0.00018 21.9 1.7 2.3 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein HMMR_N PF15905.5 KFM57516.1 - 0.00055 19.5 4.8 0.00075 19.1 4.8 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF1644 PF07800.12 KFM57516.1 - 0.0013 18.8 1.1 0.0013 18.8 1.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1644) HAP1_N PF04849.13 KFM57516.1 - 0.0015 17.8 4.9 0.002 17.4 4.9 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Snapin_Pallidin PF14712.6 KFM57516.1 - 0.0032 17.9 6.2 0.0045 17.4 6.1 1.3 1 1 0 1 1 1 1 Snapin/Pallidin Lebercilin PF15619.6 KFM57516.1 - 0.0041 16.8 3.9 0.0055 16.4 3.9 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 KFM57516.1 - 0.0072 15.7 6.3 0.01 15.2 6.3 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4515 PF14988.6 KFM57516.1 - 0.0076 16.1 5.7 0.01 15.7 5.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) BLOC1_2 PF10046.9 KFM57516.1 - 0.0082 16.4 8.3 0.073 13.4 3.6 2.9 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC144C PF14915.6 KFM57516.1 - 0.013 14.6 7.2 0.018 14.2 7.2 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region RPW8 PF05659.11 KFM57516.1 - 0.013 15.2 1.3 0.28 10.9 0.6 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF745 PF05335.13 KFM57516.1 - 0.021 14.6 4.5 0.028 14.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF5082 PF16888.5 KFM57516.1 - 0.029 14.6 6.4 0.51 10.6 0.8 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) DASH_Duo1 PF08651.10 KFM57516.1 - 0.038 13.8 1.8 0.14 12.0 0.4 2.3 1 1 2 3 3 3 0 DASH complex subunit Duo1 Prominin PF05478.11 KFM57516.1 - 0.047 11.7 2.0 0.064 11.2 2.0 1.1 1 0 0 1 1 1 0 Prominin DASH_Dam1 PF08653.10 KFM57516.1 - 0.059 13.2 0.2 0.4 10.5 0.0 2.4 2 1 0 2 2 2 0 DASH complex subunit Dam1 V_ATPase_I PF01496.19 KFM57516.1 - 0.071 11.0 2.3 0.085 10.8 2.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.7 KFM57516.1 - 0.086 13.0 6.5 0.12 12.5 6.5 1.2 1 0 0 1 1 1 0 Tropomyosin like Apo-CIII PF05778.12 KFM57516.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) ApoLp-III PF07464.11 KFM57516.1 - 0.12 12.4 9.8 0.14 12.3 2.1 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) GARP PF16731.5 KFM57516.1 - 0.13 12.0 4.6 0.51 10.0 4.6 1.8 1 1 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF948 PF06103.11 KFM57516.1 - 0.16 12.3 5.1 1.7 9.0 0.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 KFM57516.1 - 0.18 12.4 5.1 5.1 7.7 5.0 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Phage_GP20 PF06810.11 KFM57516.1 - 0.25 11.1 5.7 0.25 11.1 4.4 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 YabA PF06156.13 KFM57516.1 - 0.26 12.0 8.0 4 8.1 1.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA CCDC85 PF10226.9 KFM57516.1 - 0.28 10.8 5.9 0.45 10.2 0.3 2.1 1 1 0 2 2 2 0 CCDC85 family EzrA PF06160.12 KFM57516.1 - 0.34 9.1 9.5 0.1 10.7 2.0 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA SlyX PF04102.12 KFM57516.1 - 0.35 11.5 8.9 1.4 9.6 3.2 3.2 1 1 2 3 3 3 0 SlyX Laminin_II PF06009.12 KFM57516.1 - 0.43 10.6 7.3 0.76 9.8 7.0 1.4 1 1 0 1 1 1 0 Laminin Domain II COG5 PF10392.9 KFM57516.1 - 0.48 10.6 5.7 5.2 7.3 0.3 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF812 PF05667.11 KFM57516.1 - 0.56 9.0 9.4 1 8.2 9.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) SKA1 PF07160.12 KFM57516.1 - 0.65 9.8 8.4 0.38 10.6 1.9 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Med9 PF07544.13 KFM57516.1 - 0.66 10.1 6.7 5.3 7.2 1.8 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 KASH_CCD PF14662.6 KFM57516.1 - 0.68 9.7 11.4 0.4 10.5 1.7 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH BORCS8 PF10167.9 KFM57516.1 - 0.73 9.8 6.5 16 5.5 0.7 2.1 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 8 DUF1216 PF06746.11 KFM57516.1 - 0.78 9.7 6.1 0.32 11.0 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) LAGLIDADG_WhiA PF14527.6 KFM57516.1 - 0.8 9.8 3.5 2.7 8.1 0.3 2.1 1 1 1 2 2 2 0 WhiA LAGLIDADG-like domain FYDLN_acid PF09538.10 KFM57516.1 - 0.97 10.1 6.1 2.9 8.6 6.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Cauli_AT PF03233.13 KFM57516.1 - 1 9.3 5.3 2.9 7.8 3.7 1.9 1 1 1 2 2 2 0 Aphid transmission protein zf_UBZ PF18439.1 KFM57516.1 - 1.4 8.6 5.9 0.17 11.5 0.8 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF1664 PF07889.12 KFM57516.1 - 1.5 8.9 7.3 7.7 6.6 5.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 KFM57516.1 - 2.1 8.5 7.9 15 5.7 0.5 2.9 2 1 1 3 3 3 0 bZIP transcription factor TMPIT PF07851.13 KFM57516.1 - 2.9 7.0 5.1 4.9 6.3 5.1 1.4 1 1 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.16 KFM57516.1 - 3.8 8.0 9.0 77 3.8 9.0 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 KFM57516.1 - 3.8 7.7 9.1 14 5.9 1.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RVT_1 PF00078.27 KFM57517.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tetraspanin PF00335.20 KFM57519.1 - 6.5e-49 166.7 4.2 7.9e-49 166.4 4.2 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF1206 PF06724.11 KFM57519.1 - 6.7 6.9 8.4 7.9 6.6 3.5 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) HTH_Tnp_Tc3_2 PF01498.18 KFM57520.1 - 4.5e-16 58.8 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57520.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57520.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57520.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57520.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DB PF01682.19 KFM57521.1 - 2.7e-40 136.7 49.4 4.1e-14 52.7 8.9 4.0 3 1 1 4 4 4 4 DB module fn3 PF00041.21 KFM57521.1 - 2.8e-23 82.1 6.4 1.3e-09 38.3 0.1 4.4 3 1 0 3 3 3 3 Fibronectin type III domain V-set PF07686.17 KFM57521.1 - 8.6e-09 35.5 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFM57521.1 - 1.1e-05 25.3 0.0 7.2e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM57521.1 - 2.6e-05 24.7 0.0 0.00014 22.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM57521.1 - 0.00014 22.3 0.2 0.22 12.1 0.0 2.5 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain ig PF00047.25 KFM57521.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Receptor_2B4 PF11465.8 KFM57521.1 - 0.013 15.7 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Ig_6 PF18452.1 KFM57521.1 - 0.18 11.4 3.6 0.11 12.1 0.4 2.4 2 1 0 2 2 2 0 Immunoglobulin domain Peptidase_C48 PF02902.19 KFM57522.1 - 4.4e-12 46.3 0.2 2.1e-11 44.1 0.2 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_transf_90 PF05686.12 KFM57525.1 - 3.5e-103 345.6 1.5 4.1e-103 345.3 1.5 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KFM57525.1 - 0.095 13.1 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 MFS_1 PF07690.16 KFM57527.1 - 8.9e-13 47.9 11.8 1.4e-12 47.3 11.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3671 PF12420.8 KFM57527.1 - 0.65 10.1 4.1 0.35 11.0 1.8 1.7 2 1 0 2 2 2 0 Protein of unknown function DUF3413 PF11893.8 KFM57527.1 - 0.94 8.6 8.2 0.24 10.6 5.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) DUF3433 PF11915.8 KFM57529.1 - 0.069 13.6 0.1 0.082 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) DUF5557 PF17712.1 KFM57529.1 - 0.078 12.9 0.0 0.092 12.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5557) CN_hydrolase PF00795.22 KFM57533.1 - 2.5e-13 50.0 0.0 4.9e-13 49.0 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Adap_comp_sub PF00928.21 KFM57535.1 - 1.2e-21 77.3 0.1 1.4e-21 77.1 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family TPR_17 PF13431.6 KFM57536.1 - 2.5e-09 36.8 2.6 0.00035 20.8 0.1 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM57536.1 - 1.1e-08 35.4 0.3 0.21 12.1 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM57536.1 - 2.7e-08 33.3 10.3 0.059 13.5 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM57536.1 - 3e-08 33.8 0.1 1.3 10.0 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM57536.1 - 9.2e-06 25.9 2.2 1.2 9.5 0.2 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM57536.1 - 1.5e-05 24.6 3.5 0.17 11.6 0.1 5.0 4 1 1 5 5 5 2 TPR repeat TPR_16 PF13432.6 KFM57536.1 - 4.1e-05 24.2 0.0 3.7 8.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM57536.1 - 9.4e-05 22.6 2.3 0.92 9.8 0.5 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KFM57536.1 - 0.0012 19.1 2.1 0.67 10.3 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM57536.1 - 0.0016 18.3 1.7 0.031 14.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM57536.1 - 0.0042 16.9 15.9 0.35 10.8 0.0 7.0 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM57536.1 - 0.06 13.4 0.4 7.6 6.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2508 PF10704.9 KFM57536.1 - 0.062 13.5 5.0 3.8 7.7 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) TPR_8 PF13181.6 KFM57536.1 - 0.084 13.1 20.9 1.4 9.3 0.0 7.9 9 1 0 9 9 8 0 Tetratricopeptide repeat DUF3750 PF12570.8 KFM57536.1 - 0.18 12.5 0.2 0.58 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3750) TipAS PF07739.13 KFM57536.1 - 0.19 12.3 3.8 11 6.6 0.0 3.5 3 1 1 4 4 4 0 TipAS antibiotic-recognition domain TPR_6 PF13174.6 KFM57536.1 - 0.21 12.3 1.7 23 5.9 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat V-SNARE PF05008.15 KFM57536.1 - 4.6 7.7 12.0 19 5.7 1.4 4.3 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DUF261 PF03196.13 KFM57537.1 - 1.1 9.3 10.5 0.75 9.9 8.8 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF261 RCC1 PF00415.18 KFM57538.1 - 5.5e-21 74.9 0.3 1.4e-10 41.6 0.0 2.1 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM57538.1 - 4.8e-11 42.2 8.6 1.8e-05 24.4 0.4 3.2 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat HTH_Tnp_Tc3_2 PF01498.18 KFM57539.1 - 2.5e-16 59.7 2.2 4.5e-16 58.8 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57539.1 - 9.8e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM57540.1 - 1e-38 130.1 47.7 4.7e-08 33.1 2.9 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57540.1 - 1e-25 88.7 56.1 1.4e-05 25.3 0.4 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57540.1 - 1.2e-20 72.3 50.1 0.00038 21.0 0.4 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFM57540.1 - 1.5e-15 56.9 42.3 0.00018 21.8 0.7 6.5 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM57540.1 - 4.3e-07 30.1 37.5 0.0089 16.3 1.7 7.1 6 1 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM57540.1 - 5.2e-07 29.5 43.0 0.089 12.8 1.6 7.2 6 1 0 6 6 6 5 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM57540.1 - 0.00013 22.0 19.3 2.7 8.1 0.3 6.0 4 1 2 6 6 6 2 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM57540.1 - 0.00013 21.7 13.3 1.5 8.6 1.8 5.6 1 1 5 6 6 6 2 GAGA factor BolA PF01722.18 KFM57540.1 - 0.00021 21.5 9.0 2.8 8.3 3.4 4.2 1 1 3 4 4 4 2 BolA-like protein Baculo_IE-1 PF05290.11 KFM57540.1 - 0.0056 16.6 19.1 1 9.3 9.6 4.8 1 1 1 3 3 3 1 Baculovirus immediate-early protein (IE-0) zf_UBZ PF18439.1 KFM57540.1 - 0.0072 15.9 19.8 4.4 7.0 0.2 6.1 6 0 0 6 6 6 1 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM57540.1 - 0.014 15.3 0.6 0.16 11.9 0.1 5.8 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM57540.1 - 0.11 12.4 20.2 8.4 6.3 0.1 5.6 2 1 4 6 6 6 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 KFM57540.1 - 0.17 12.0 27.4 1.9 8.7 3.2 5.4 1 1 3 5 5 5 0 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KFM57540.1 - 0.19 12.1 39.1 3 8.2 3.5 5.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zinc-ribbons_6 PF07191.12 KFM57540.1 - 0.46 10.5 23.8 1.5 8.9 1.7 4.8 1 1 3 4 4 4 0 zinc-ribbons Prok-RING_2 PF14445.6 KFM57540.1 - 0.61 10.3 15.2 16 5.7 0.0 5.6 5 1 1 6 6 6 0 Prokaryotic RING finger family 2 TRAF6_Z2 PF18048.1 KFM57540.1 - 0.66 10.1 0.1 0.66 10.1 0.1 6.0 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 TerY_C PF15616.6 KFM57540.1 - 3.2 7.9 9.9 2.3 8.3 0.1 3.4 2 2 1 3 3 3 0 TerY-C metal binding domain DUF2256 PF10013.9 KFM57540.1 - 3.5 7.8 20.8 13 6.0 0.1 5.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFM57540.1 - 8.7 6.0 31.9 3 7.5 0.0 5.9 1 1 5 6 6 6 0 MYST family zinc finger domain DUF4779 PF16009.5 KFM57541.1 - 1.7e-07 31.4 84.2 1.7e-07 31.4 84.2 5.0 1 1 3 4 4 4 1 Domain of unknown function (DUF4779) COesterase PF00135.28 KFM57542.1 - 5.8e-27 94.7 0.0 6.5e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family HTH_Tnp_Tc3_2 PF01498.18 KFM57543.1 - 4.3e-16 58.9 3.5 5.8e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57543.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57543.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57543.1 - 0.0027 17.5 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57543.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57544.1 - 1.2e-16 60.7 4.5 4.6e-16 58.8 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57544.1 - 9.6e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57545.1 - 6.5e-12 45.4 0.0 7.1e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease OAR PF03826.17 KFM57546.1 - 0.0047 16.7 3.0 0.017 15.0 3.0 2.1 1 0 0 1 1 1 1 OAR domain Macoilin PF09726.9 KFM57546.1 - 0.09 11.3 9.3 0.096 11.2 9.3 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 KFM57546.1 - 0.18 11.4 20.2 0.26 10.9 20.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 KFM57546.1 - 0.68 9.9 6.6 0.87 9.6 6.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 KFM57546.1 - 2.4 6.2 10.6 2.8 6.0 10.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1387 PF07139.11 KFM57546.1 - 3.8 7.2 12.4 4.6 6.9 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Lin-8 PF03353.15 KFM57546.1 - 8 5.9 9.3 10 5.6 9.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDP_N PF12278.8 KFM57546.1 - 8.3 6.5 12.6 8.2 6.6 11.7 1.4 1 1 0 1 1 1 0 Sex determination protein N terminal HTH_Tnp_Tc3_2 PF01498.18 KFM57547.1 - 3.5e-12 46.4 3.7 3.8e-12 46.3 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57547.1 - 5.7e-10 39.1 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_IclR PF09339.10 KFM57547.1 - 5.7e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_32 PF13565.6 KFM57547.1 - 0.00068 20.2 17.1 0.02 15.5 3.3 3.5 1 1 2 3 3 3 2 Homeodomain-like domain MarR_2 PF12802.7 KFM57547.1 - 0.0012 18.7 0.1 0.0034 17.2 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 KFM57547.1 - 0.034 13.9 1.8 0.062 13.1 0.4 2.2 2 0 0 2 2 2 0 Homeodomain-like domain WH1 PF00568.23 KFM57548.1 - 0.0001 22.2 0.1 0.00021 21.2 0.0 1.5 1 1 1 2 2 2 1 WH1 domain LEF-9 PF05094.12 KFM57549.1 - 0.032 12.8 0.5 0.03 12.9 0.5 1.0 1 0 0 1 1 1 0 Late expression factor 9 (LEF-9) DUF2052 PF09747.9 KFM57550.1 - 2.7e-43 148.4 25.8 3.4e-41 141.6 25.8 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) NHS PF15273.6 KFM57550.1 - 2.6 7.0 4.6 3.5 6.6 4.6 1.1 1 0 0 1 1 1 0 NHS-like Sacchrp_dh_NADP PF03435.18 KFM57551.1 - 6e-19 68.6 0.0 8.5e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KFM57551.1 - 0.03 14.2 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3Beta_HSD PF01073.19 KFM57551.1 - 0.036 13.1 0.1 0.057 12.4 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Exo_endo_phos_2 PF14529.6 KFM57552.1 - 2.7e-16 59.5 0.1 8.4e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RT_RNaseH_2 PF17919.1 KFM57554.1 - 1.5e-33 114.8 0.2 1.4e-32 111.7 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM57554.1 - 2.2e-26 92.2 0.0 5.7e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM57554.1 - 1.3e-19 70.6 0.1 1.3e-19 70.6 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM57554.1 - 1.8e-19 70.1 0.0 4.5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM57554.1 - 7.3e-17 61.2 0.3 2.8e-16 59.4 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM57554.1 - 0.0032 17.7 0.1 0.028 14.7 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger zf-CCHC PF00098.23 KFM57554.1 - 0.019 15.0 2.0 0.019 15.0 2.0 2.9 2 0 0 2 2 2 0 Zinc knuckle DUF4817 PF16087.5 KFM57555.1 - 2.9e-08 33.4 0.1 8.9e-08 31.8 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 KFM57555.1 - 6.2e-06 26.7 0.6 4.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57555.1 - 0.0059 16.4 0.3 1.7 8.6 0.1 2.7 2 0 0 2 2 2 2 Homeodomain-like domain CENP-B_N PF04218.13 KFM57555.1 - 0.015 14.9 0.2 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 KFM57555.1 - 0.029 14.5 0.3 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Mga PF05043.13 KFM57555.1 - 0.064 13.8 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_29 PF13551.6 KFM57555.1 - 0.091 12.8 0.3 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix Atg8 PF02991.16 KFM57557.1 - 2.1e-32 111.4 0.0 2.9e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFM57557.1 - 0.026 14.9 0.0 0.038 14.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 PC4 PF02229.16 KFM57558.1 - 5.7e-07 29.1 0.6 5.3e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) Acyltransferase PF01553.21 KFM57560.1 - 2.4e-16 59.6 0.0 4.4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF507 PF04368.13 KFM57560.1 - 0.032 14.2 0.3 0.062 13.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF507) DUF389 PF04087.14 KFM57561.1 - 1.5e-46 157.9 7.9 2.5e-46 157.3 7.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF389) PHO4 PF01384.20 KFM57561.1 - 0.24 10.4 4.7 0.58 9.1 4.6 1.5 1 1 0 1 1 1 0 Phosphate transporter family Transposase_1 PF01359.18 KFM57566.1 - 1.5e-21 76.0 0.2 4.5e-21 74.5 0.2 1.9 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM57566.1 - 2.6e-08 33.9 0.0 6.8e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM57566.1 - 7.7e-07 29.6 0.0 4.2e-06 27.3 0.0 2.4 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 KFM57566.1 - 0.00023 21.0 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57566.1 - 0.027 14.7 0.2 0.53 10.6 0.3 2.6 2 0 0 2 2 2 0 Transposase HTH_29 PF13551.6 KFM57566.1 - 0.061 13.3 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 KFM57566.1 - 0.15 12.2 0.0 0.48 10.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Acyl_transf_3 PF01757.22 KFM57567.1 - 1.3e-23 83.7 37.5 1.3e-23 83.7 37.5 1.7 2 0 0 2 2 2 1 Acyltransferase family DUF308 PF03729.13 KFM57567.1 - 0.058 13.7 0.4 0.058 13.7 0.4 3.5 5 0 0 5 5 5 0 Short repeat of unknown function (DUF308) Kinesin PF00225.23 KFM57569.1 - 3.3e-33 115.0 0.1 3.8e-33 114.8 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM57569.1 - 3.5e-05 23.8 0.0 7.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 KFM57570.1 - 2.7e-45 154.8 0.0 2.7e-45 154.8 0.0 2.1 3 0 0 3 3 3 1 Kinesin motor domain Cnn_1N PF07989.11 KFM57570.1 - 0.0011 19.1 5.8 0.0011 19.1 5.8 3.3 3 0 0 3 3 3 1 Centrosomin N-terminal motif 1 ZYG-11_interact PF05884.12 KFM57570.1 - 0.14 11.5 1.2 0.24 10.8 1.2 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 AAA_13 PF13166.6 KFM57571.1 - 0.0027 16.4 4.6 0.0027 16.4 4.6 2.0 2 0 0 2 2 2 1 AAA domain DUF4411 PF14367.6 KFM57571.1 - 0.0027 17.6 1.2 0.0027 17.6 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4411) Xrn1_D3 PF18194.1 KFM57571.1 - 0.014 15.5 0.1 0.046 13.8 0.1 2.0 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 APG6_N PF17675.1 KFM57571.1 - 0.026 15.1 30.4 0.066 13.7 15.9 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Tho2 PF11262.8 KFM57571.1 - 0.028 13.6 22.8 0.25 10.5 9.2 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 GAS PF13851.6 KFM57571.1 - 1.7 8.0 37.5 3.9 6.8 7.0 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Adhesin_P1_N PF18652.1 KFM57571.1 - 2.6 8.1 6.7 3.7 7.6 0.7 2.8 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain DUF948 PF06103.11 KFM57571.1 - 3.6 7.9 8.5 1.7 9.0 0.4 3.3 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.11 KFM57571.1 - 3.7 7.7 34.7 0.76 10.0 20.8 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 KFM57571.1 - 6.6 7.0 34.2 1.6 9.0 9.3 4.0 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) ERM PF00769.19 KFM57571.1 - 7.6 6.3 34.8 9 6.0 32.8 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Prefoldin_2 PF01920.20 KFM57571.1 - 8.2 6.4 36.9 0.18 11.8 8.6 3.3 2 1 0 2 2 2 0 Prefoldin subunit WD40 PF00400.32 KFM57573.1 - 6.3e-22 77.5 7.8 0.00013 22.7 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KFM57573.1 - 8.1e-07 28.1 0.2 0.32 9.6 0.0 4.5 1 1 4 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFM57573.1 - 7e-06 26.3 0.2 2.4 8.5 0.0 4.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4164 PF13747.6 KFM57574.1 - 0.038 14.3 1.2 0.038 14.3 1.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Laminin_II PF06009.12 KFM57574.1 - 0.51 10.3 15.8 0.85 9.6 5.9 2.8 2 1 0 2 2 2 0 Laminin Domain II Rtt102p PF09510.10 KFM57574.1 - 3.2 8.0 10.7 0.55 10.4 2.2 2.5 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein DUF1664 PF07889.12 KFM57574.1 - 4.3 7.4 10.5 9.6 6.3 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Med4 PF10018.9 KFM57574.1 - 5.3 6.7 17.1 1.6 8.4 5.4 2.4 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Phage_GPO PF05929.11 KFM57574.1 - 5.9 6.4 10.6 9.7 5.7 1.0 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Guanylate_cyc PF00211.20 KFM57577.1 - 9.2e-60 201.4 0.0 1.2e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFM57577.1 - 0.00031 20.3 1.8 0.00042 19.8 1.8 1.2 1 0 0 1 1 1 1 Heme NO binding associated DUF4761 PF15958.5 KFM57577.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) Alk_phosphatase PF00245.20 KFM57578.1 - 2.9e-18 66.0 0.0 3.4e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Rho_Binding PF08912.11 KFM57579.1 - 1.4e-17 64.3 11.4 1.4e-17 64.3 11.4 4.3 3 1 1 4 4 4 1 Rho Binding PH PF00169.29 KFM57579.1 - 8.7e-09 35.8 0.5 0.0022 18.5 0.0 3.2 3 0 0 3 3 3 2 PH domain C1_1 PF00130.22 KFM57579.1 - 6.1e-06 26.0 2.2 1.3e-05 25.0 2.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH_9 PF15410.6 KFM57579.1 - 0.043 14.2 1.2 5.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain C1_2 PF03107.16 KFM57579.1 - 0.096 13.0 0.5 0.2 12.0 0.5 1.5 1 0 0 1 1 1 0 C1 domain Fez1 PF06818.15 KFM57579.1 - 0.21 12.0 35.6 0.061 13.8 23.0 3.0 2 1 1 3 3 3 0 Fez1 L31 PF09784.9 KFM57579.1 - 0.86 10.1 11.2 0.71 10.3 3.6 3.4 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 Golgin_A5 PF09787.9 KFM57579.1 - 2.3 7.6 31.9 6.1 6.2 14.0 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 KFM57579.1 - 2.3 7.0 36.2 5 5.9 15.1 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KFM57579.1 - 3.8 7.0 18.1 6.9 6.1 18.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Streptin-Immun PF11083.8 KFM57579.1 - 5.2 7.5 22.5 0.19 12.1 8.1 3.3 1 1 2 3 3 3 0 Lantibiotic streptin immunity protein Collagen PF01391.18 KFM57580.1 - 1.1e-68 226.8 237.2 3e-10 39.7 23.8 8.2 3 2 4 7 7 7 7 Collagen triple helix repeat (20 copies) Laminin_G_2 PF02210.24 KFM57580.1 - 0.0016 19.0 0.0 0.0025 18.4 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM57580.1 - 0.015 15.5 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Laminin G domain Collagen PF01391.18 KFM57581.1 - 3.1e-12 46.1 55.5 5e-07 29.4 25.2 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Homeodomain PF00046.29 KFM57583.1 - 7.3e-24 83.4 6.3 1.6e-23 82.3 6.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM57583.1 - 0.00029 20.7 0.9 0.00055 19.8 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain SatD PF16264.5 KFM57583.1 - 0.23 11.0 0.1 0.31 10.6 0.1 1.1 1 0 0 1 1 1 0 SatD family (SatD) Annexin PF00191.20 KFM57586.1 - 1.7e-14 53.6 0.2 1.9e-14 53.5 0.2 1.0 1 0 0 1 1 1 1 Annexin Cnd3 PF12719.7 KFM57586.1 - 0.12 11.6 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain RRM_1 PF00076.22 KFM57587.1 - 1.8e-17 62.9 0.2 2.8e-07 30.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TipAS PF07739.13 KFM57587.1 - 0.00089 19.8 1.5 3.3 8.3 0.1 3.4 2 1 0 3 3 3 1 TipAS antibiotic-recognition domain Nucleolin_bd PF16725.5 KFM57587.1 - 0.01 15.5 5.6 5.2 6.8 0.1 3.8 3 0 0 3 3 3 0 Nucleolin binding domain UPF0223 PF05256.12 KFM57587.1 - 0.096 13.0 2.8 0.82 10.1 0.1 3.3 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0223) DUF3835 PF12927.7 KFM57587.1 - 0.26 12.1 4.5 34 5.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3835) DUF2383 PF09537.10 KFM57587.1 - 0.3 11.4 3.5 4.7 7.6 0.5 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) Fzo_mitofusin PF04799.13 KFM57587.1 - 1.2 8.6 10.2 0.088 12.3 1.4 2.4 2 0 0 2 2 2 0 fzo-like conserved region RecG_N PF17190.4 KFM57587.1 - 1.7 9.4 4.8 11 6.8 0.0 3.6 4 1 1 5 5 4 0 RecG N-terminal helical domain LPD30 PF18850.1 KFM57587.1 - 1.8 8.4 6.5 10 5.9 0.1 2.9 3 0 0 3 3 3 0 Large polyvalent protein associated domain 30 MutS_II PF05188.17 KFM57587.1 - 2.5 8.4 8.4 1.4 9.2 0.6 2.9 1 1 2 3 3 3 0 MutS domain II DUF445 PF04286.12 KFM57587.1 - 2.9 7.6 9.2 5.4 6.7 6.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DDE_Tnp_1_7 PF13843.6 KFM57588.1 - 6.7e-70 236.1 0.1 7.8e-70 235.9 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM57588.1 - 6.5e-05 22.7 0.0 8.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_3 PF13358.6 KFM57590.1 - 2e-09 37.4 0.0 2.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57591.1 - 0.0018 18.1 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57593.1 - 7.6e-13 48.4 0.0 1.4e-10 41.1 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57594.1 - 2.1e-16 59.9 2.2 4.4e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57594.1 - 9.5e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-TRAF PF02176.18 KFM57595.1 - 4.2e-36 123.4 34.8 5.7e-15 55.7 3.5 4.2 1 1 3 4 4 4 4 TRAF-type zinc finger zf-C2HC_2 PF13913.6 KFM57595.1 - 0.00012 21.9 12.6 0.00048 19.9 0.6 3.9 3 0 0 3 3 3 2 zinc-finger of a C2HC-type DUF2318 PF10080.9 KFM57595.1 - 0.0031 17.6 7.3 0.16 12.1 0.5 2.4 1 1 1 2 2 2 2 Predicted membrane protein (DUF2318) zf-LYAR PF08790.11 KFM57595.1 - 0.66 9.9 6.8 5.8 6.9 0.9 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf_C2H2_10 PF18414.1 KFM57595.1 - 1.2 8.7 8.6 2 8.1 0.1 4.0 4 0 0 4 4 4 0 C2H2 type zinc-finger Evr1_Alr PF04777.13 KFM57595.1 - 1.5 9.3 6.6 2.1 8.8 1.6 2.4 1 1 0 2 2 2 0 Erv1 / Alr family Sld5 PF05916.11 KFM57597.1 - 5e-23 81.7 0.3 6.7e-23 81.2 0.3 1.2 1 0 0 1 1 1 1 GINS complex protein ACOX PF01756.19 KFM57598.1 - 1.9e-24 86.2 0.0 2e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA oxidase DDE_3 PF13358.6 KFM57599.1 - 8.2e-14 51.6 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57599.1 - 2.4e-08 34.1 1.4 1.3e-06 28.6 2.1 2.4 2 0 0 2 2 2 1 Transposase GATA PF00320.27 KFM57600.1 - 6.7e-29 99.2 17.5 6e-15 54.6 6.8 2.8 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFM57600.1 - 3e-05 23.4 10.9 0.0035 16.8 1.6 3.0 3 0 0 3 3 3 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KFM57600.1 - 0.037 14.1 3.2 1.2 9.4 0.3 2.9 2 1 1 3 3 3 0 Zinc ribbon domain Prim_Zn_Ribbon PF08273.12 KFM57600.1 - 0.34 11.2 8.7 0.69 10.2 0.7 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.7 KFM57600.1 - 0.57 10.2 6.6 12 6.0 0.5 2.7 1 1 0 2 2 2 0 Double zinc ribbon Auto_anti-p27 PF06677.12 KFM57600.1 - 1.2 9.4 5.6 4.3 7.6 0.4 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KFM57600.1 - 6.7 6.6 8.2 11 6.0 1.2 3.1 3 0 0 3 3 3 0 Domain found in IF2B/IF5 DUF2475 PF10629.9 KFM57603.1 - 0.024 14.9 0.2 0.047 13.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) Myotub-related PF06602.14 KFM57604.1 - 3.4e-134 447.2 0.1 5.2e-134 446.6 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFM57604.1 - 0.0028 17.2 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM57604.1 - 0.011 15.6 0.0 0.036 13.9 0.0 1.9 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM57604.1 - 0.028 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4283 PF14111.6 KFM57606.1 - 3e-05 23.6 0.1 4.9 6.7 0.0 4.9 1 1 5 6 6 6 2 Domain of unknown function (DUF4283) Clathrin PF00637.20 KFM57606.1 - 0.00035 20.4 5.6 12 5.7 0.0 5.7 3 2 3 6 6 6 3 Region in Clathrin and VPS BA14K PF07886.11 KFM57606.1 - 0.058 13.3 17.7 1.2e+02 2.7 0.1 7.5 7 0 0 7 7 7 0 BA14K-like protein CFEM PF05730.11 KFM57606.1 - 8.3 6.6 26.0 0.15 12.2 0.6 5.3 1 1 5 6 6 6 0 CFEM domain HTH_Tnp_Tc3_2 PF01498.18 KFM57608.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57608.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 KFM57609.1 - 2.5e-76 257.3 0.0 2.9e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Ldl_recept_b PF00058.17 KFM57610.1 - 1.1e-16 61.0 1.3 9.8e-10 38.8 0.0 2.6 3 0 0 3 3 3 2 Low-density lipoprotein receptor repeat class B Ldl_recept_b PF00058.17 KFM57611.1 - 3.6e-26 91.4 1.3 2.8e-11 43.7 0.0 3.1 3 0 0 3 3 3 3 Low-density lipoprotein receptor repeat class B SGL PF08450.12 KFM57611.1 - 9.8e-07 28.6 0.9 5.7e-05 22.8 0.1 1.9 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region FXa_inhibition PF14670.6 KFM57612.1 - 2.2e-08 34.3 7.3 3.6e-08 33.5 7.3 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.17 KFM57612.1 - 0.0016 18.8 0.5 0.003 18.0 0.5 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor repeat class B zf-SNAP50_C PF12251.8 KFM57613.1 - 5.1e-66 222.2 6.7 6.7e-66 221.8 6.7 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-Dof PF02701.15 KFM57613.1 - 0.49 10.6 3.6 1.2 9.4 3.6 1.6 1 0 0 1 1 1 0 Dof domain, zinc finger DUF4603 PF15376.6 KFM57615.1 - 0.0076 13.7 0.5 0.0076 13.7 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) DUF1235 PF06822.12 KFM57615.1 - 0.074 12.3 0.1 0.074 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) HSP70 PF00012.20 KFM57617.1 - 5.2e-99 332.1 3.1 6.1e-99 331.8 3.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM57617.1 - 5.6e-18 64.8 1.2 3e-17 62.4 0.3 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KFM57617.1 - 0.042 13.1 0.1 0.096 11.9 0.0 1.5 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase Pkinase_Tyr PF07714.17 KFM57618.1 - 1.3e-42 145.9 0.0 2.6e-42 144.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM57618.1 - 1.1e-21 77.4 0.0 2.7e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain DDE_3 PF13358.6 KFM57620.1 - 4.8e-16 58.8 0.1 5.9e-15 55.3 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57620.1 - 8e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57620.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57620.1 - 0.0018 18.0 0.0 0.082 12.7 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57620.1 - 0.014 15.5 0.1 0.061 13.5 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57620.1 - 0.023 14.7 2.1 0.032 14.3 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM57620.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase LCCL PF03815.19 KFM57621.1 - 1.5e-21 76.3 0.7 4e-21 74.9 0.7 1.7 1 0 0 1 1 1 1 LCCL domain Sushi PF00084.20 KFM57621.1 - 6.8e-15 55.4 8.0 2.4e-11 44.1 0.6 2.9 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) HRM PF02793.22 KFM57621.1 - 0.042 14.2 2.7 6.1 7.2 0.1 3.2 3 0 0 3 3 3 0 Hormone receptor domain Rxt3 PF08642.10 KFM57621.1 - 0.08 13.7 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Sushi PF00084.20 KFM57622.1 - 3.6e-11 43.5 6.9 2.3e-05 24.9 0.0 3.3 2 1 0 2 2 2 2 Sushi repeat (SCR repeat) Peptidase_M24 PF00557.24 KFM57623.1 - 1.1e-06 28.5 0.0 1.2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ank_3 PF13606.6 KFM57624.1 - 8.1e-12 44.2 0.2 0.052 14.1 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KFM57624.1 - 1.1e-11 45.1 0.0 3.2e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM57624.1 - 1.5e-11 44.5 0.2 0.0002 21.9 0.1 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM57624.1 - 1.7e-10 41.0 0.1 8.2e-06 26.0 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM57624.1 - 5.7e-08 32.9 0.3 0.003 17.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Thymosin PF01290.20 KFM57624.1 - 1.6 8.6 7.5 0.055 13.2 0.9 2.1 2 0 0 2 2 2 0 Thymosin beta-4 family HTH_Tnp_Tc3_2 PF01498.18 KFM57625.1 - 9.8e-11 41.7 1.0 1.6e-10 41.1 1.0 1.4 1 0 0 1 1 1 1 Transposase 2OG-FeII_Oxy_2 PF13532.6 KFM57626.1 - 4e-22 79.4 0.1 1.1e-21 77.9 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily HTH_Tnp_Tc3_2 PF01498.18 KFM57626.1 - 4.2e-17 62.2 1.3 9.6e-17 61.0 1.3 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57626.1 - 2.8e-06 27.8 7.2 9.1e-06 26.2 2.8 2.9 3 0 0 3 3 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM57626.1 - 0.0033 17.4 2.0 0.0057 16.6 0.1 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_3 PF01381.22 KFM57626.1 - 0.0042 17.1 0.6 0.074 13.1 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix MarR_2 PF12802.7 KFM57626.1 - 0.005 16.7 0.3 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_28 PF13518.6 KFM57626.1 - 0.01 15.9 1.7 0.082 13.0 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PAX PF00292.18 KFM57626.1 - 0.016 15.1 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 'Paired box' domain RE_NgoBV PF09564.10 KFM57626.1 - 0.032 13.7 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 NgoBV restriction endonuclease HTH_23 PF13384.6 KFM57626.1 - 0.071 12.9 1.4 0.6 10.0 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 KFM57626.1 - 0.23 11.0 1.3 1.6 8.3 0.0 2.6 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 KFM57627.1 - 2.5e-19 69.3 0.6 2.5e-19 69.3 0.6 2.3 2 1 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM57627.1 - 6.5e-10 39.5 0.5 5.7e-09 36.5 0.0 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57627.1 - 1.6e-07 31.0 0.3 9.3e-07 28.5 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM57627.1 - 2.7e-07 30.5 0.6 5.4e-07 29.5 0.1 1.9 2 0 0 2 2 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 KFM57627.1 - 1.2e-05 24.9 0.1 2.6e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 KFM57627.1 - 1.2e-05 25.3 0.6 0.0013 18.8 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_21 PF13276.6 KFM57627.1 - 5e-05 23.3 1.2 0.0001 22.3 0.5 1.8 2 0 0 2 2 2 1 HTH-like domain HTH_Tnp_ISL3 PF13542.6 KFM57627.1 - 0.00021 20.6 0.2 0.00069 19.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 KFM57627.1 - 0.00036 20.0 0.1 0.037 13.6 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 KFM57627.1 - 0.00038 20.0 0.2 0.00072 19.1 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KFM57627.1 - 0.00047 19.9 3.7 0.0007 19.3 0.3 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM57627.1 - 0.0042 16.6 0.1 0.01 15.3 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_IS630 PF01710.16 KFM57627.1 - 0.0082 16.2 0.8 0.019 15.0 0.1 1.8 2 0 0 2 2 2 1 Transposase UPF0122 PF04297.14 KFM57627.1 - 0.0086 16.3 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_7 PF02796.15 KFM57627.1 - 0.026 14.6 2.3 0.28 11.3 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase TnsD PF15978.5 KFM57627.1 - 0.03 13.3 0.5 0.06 12.3 0.2 1.7 2 0 0 2 2 2 0 Tn7-like transposition protein D Mor PF08765.11 KFM57627.1 - 0.082 12.9 0.3 0.25 11.3 0.3 1.8 1 0 0 1 1 1 0 Mor transcription activator family HTH_Tnp_1 PF01527.20 KFM57627.1 - 0.089 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE_Tnp_ISAZ013 PF07592.11 KFM57627.1 - 0.1 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain HTH_1 PF00126.27 KFM57627.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_40 PF14493.6 KFM57627.1 - 0.14 12.6 0.2 0.34 11.4 0.2 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.6 KFM57628.1 - 3.5e-12 46.3 0.0 6.2e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_3 PF01381.22 KFM57629.1 - 0.021 14.9 0.2 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_31 PF13560.6 KFM57629.1 - 0.031 14.6 2.3 0.12 12.7 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_28 PF13518.6 KFM57629.1 - 0.052 13.7 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM57629.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DDE_1 PF03184.19 KFM57630.1 - 4.1e-50 169.8 0.1 7.5e-50 169.0 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM57630.1 - 1.9e-12 47.0 0.0 1.6e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM57630.1 - 0.00092 18.8 0.0 0.0031 17.1 0.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM57631.1 - 4.1e-16 59.0 3.0 6e-16 58.5 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57631.1 - 1.1e-13 51.2 0.0 2.4e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease SNF PF00209.18 KFM57632.1 - 1.4e-201 670.8 46.4 1.6e-201 670.6 46.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family ubiquitin PF00240.23 KFM57633.1 - 7.9e-18 64.0 0.2 1.3e-17 63.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Tugs PF17840.1 KFM57633.1 - 4.6e-14 52.3 1.5 1.1e-13 51.1 1.5 1.6 1 0 0 1 1 1 1 Tethering Ubl4a to BAGS domain Rad60-SLD PF11976.8 KFM57633.1 - 4.9e-08 32.7 0.2 1.3e-07 31.3 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFM57633.1 - 0.033 14.7 0.1 0.062 13.9 0.0 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 KFM57633.1 - 0.05 13.5 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain MIF4G PF02854.19 KFM57634.1 - 5.8e-38 130.6 2.9 5.8e-38 130.6 2.9 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KFM57634.1 - 1.3e-09 38.0 2.6 1.3e-09 38.0 2.6 2.2 2 0 0 2 2 2 1 MA3 domain DUF3677 PF12432.8 KFM57634.1 - 0.32 11.3 4.2 0.27 11.6 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) Snf7 PF03357.21 KFM57634.1 - 3.1 7.4 14.1 1.7 8.2 6.0 2.9 2 1 1 3 3 3 0 Snf7 tRNA_bind_2 PF13725.6 KFM57636.1 - 3e-49 167.8 2.4 3e-49 167.8 2.4 2.3 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KFM57636.1 - 1.5e-40 138.9 0.0 2.9e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 Helicase GNAT_acetyltr_2 PF13718.6 KFM57636.1 - 1.3e-36 126.1 0.0 7.7e-35 120.3 0.0 2.6 2 0 0 2 2 2 1 GNAT acetyltransferase 2 DUF1726 PF08351.11 KFM57636.1 - 3.3e-18 65.4 0.1 1.3e-16 60.3 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) Helicase_C_2 PF13307.6 KFM57636.1 - 0.057 13.6 0.2 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 Helicase C-terminal domain Sigma70_r4 PF04545.16 KFM57636.1 - 0.068 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 PHD PF00628.29 KFM57637.1 - 1e-09 38.1 10.7 1e-09 38.1 10.7 2.4 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KFM57637.1 - 8.5e-09 35.6 5.1 8.5e-09 35.6 5.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KFM57637.1 - 1.9e-07 30.8 5.6 1.9e-07 30.8 5.6 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM57637.1 - 1.9e-06 27.8 6.7 1.9e-06 27.8 6.7 2.5 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFM57637.1 - 6.4e-06 25.9 2.6 6.4e-06 25.9 2.6 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM57637.1 - 7.4e-06 25.7 4.3 7.4e-06 25.7 4.3 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM57637.1 - 1.9e-05 24.9 2.6 1.9e-05 24.9 2.6 3.2 2 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM57637.1 - 0.00014 21.7 3.3 0.00014 21.7 3.3 2.7 2 1 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM57637.1 - 0.0002 21.2 1.7 0.0002 21.2 1.7 3.8 3 1 0 3 3 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFM57637.1 - 0.004 17.3 6.0 0.004 17.3 6.0 3.4 3 2 0 3 3 2 1 zinc finger of C3HC4-type, RING C4 PF01413.19 KFM57637.1 - 0.0081 16.5 0.6 0.02 15.3 0.6 1.7 1 0 0 1 1 1 1 C-terminal tandem repeated domain in type 4 procollagen zf-RING_11 PF17123.5 KFM57637.1 - 0.017 14.9 3.6 0.017 14.9 3.6 2.8 2 1 0 2 2 1 0 RING-like zinc finger EFTUD2 PF16004.5 KFM57637.1 - 0.27 11.8 7.4 0.5 10.9 7.4 1.4 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus NAM-associated PF14303.6 KFM57637.1 - 1.1 10.0 13.1 1 10.1 1.8 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DZR PF12773.7 KFM57637.1 - 3.7 7.7 14.5 3.2 7.9 1.8 2.9 2 1 0 2 2 2 0 Double zinc ribbon Nop14 PF04147.12 KFM57637.1 - 4.2 5.5 10.6 5.7 5.0 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KFM57637.1 - 4.3 5.3 14.4 5.8 4.9 14.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 KFM57637.1 - 9.9 5.1 10.0 15 4.5 10.0 1.1 1 0 0 1 1 1 0 Pes-10 PX PF00787.24 KFM57640.1 - 2e-19 69.6 2.2 2.6e-19 69.3 0.9 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KFM57640.1 - 3.1e-18 66.2 14.4 1.3e-12 47.7 6.4 2.4 1 1 1 2 2 2 2 Vps5 C terminal like DUF1048 PF06304.11 KFM57640.1 - 0.012 16.0 1.2 0.21 12.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) KdpC PF02669.15 KFM57641.1 - 0.056 13.3 0.0 0.056 13.3 0.0 1.1 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DUF3772 PF12607.8 KFM57641.1 - 0.39 10.5 2.5 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) MIF4G PF02854.19 KFM57642.1 - 4.6e-40 137.5 14.2 8.1e-27 94.2 2.1 3.5 3 0 0 3 3 3 3 MIF4G domain MRP-S23 PF10484.9 KFM57642.1 - 0.43 10.8 3.2 6.4 7.1 0.4 3.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 DUF2218 PF09981.9 KFM57642.1 - 0.44 11.0 2.0 32 5.0 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) Upf2 PF04050.14 KFM57643.1 - 1.5e-30 106.7 6.0 1.5e-30 106.7 6.0 1.9 2 0 0 2 2 2 1 Up-frameshift suppressor 2 MIF4G PF02854.19 KFM57643.1 - 7e-23 81.4 0.0 1.6e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 MIF4G domain TSP_1 PF00090.19 KFM57644.1 - 3.1e-55 184.2 80.4 1.1e-14 54.4 6.0 6.6 6 1 0 6 6 6 6 Thrombospondin type 1 domain Transposase_1 PF01359.18 KFM57645.1 - 7.7e-14 51.3 0.1 4.5e-13 48.8 0.0 2.3 3 0 0 3 3 3 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM57645.1 - 3.9e-05 23.4 0.1 0.00018 21.3 0.1 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF4211 PF13926.6 KFM57646.1 - 5.1e-17 62.3 0.0 1.1e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) RVT_1 PF00078.27 KFM57647.1 - 1.5e-23 83.5 0.0 2.3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WSD PF15613.6 KFM57648.1 - 0.0021 18.5 0.5 0.0021 18.5 0.5 2.9 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KFM57648.1 - 0.037 14.3 0.1 0.067 13.5 0.1 1.4 1 0 0 1 1 1 0 DDT domain KA1 PF02149.19 KFM57649.1 - 0.12 12.2 0.0 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 Kinase associated domain 1 Pkinase PF00069.25 KFM57650.1 - 5.1e-27 94.9 0.0 5.3e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57650.1 - 7.8e-16 58.1 0.0 8.2e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM57650.1 - 8.2e-06 25.9 0.0 9.8e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFM57650.1 - 0.00043 19.9 0.2 0.00088 18.9 0.2 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KFM57650.1 - 0.00054 19.4 0.0 0.00054 19.4 0.0 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFM57650.1 - 0.0017 17.4 0.0 0.0017 17.4 0.0 1.0 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFM57650.1 - 0.036 13.7 0.0 0.037 13.6 0.0 1.0 1 0 0 1 1 1 0 RIO1 family Glycos_trans_3N PF02885.17 KFM57650.1 - 0.085 12.7 0.0 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 Glycosyl transferase family, helical bundle domain YukC PF10140.9 KFM57650.1 - 0.22 10.3 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC HTH_Tnp_Tc3_2 PF01498.18 KFM57651.1 - 4.8e-16 58.8 3.5 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57651.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57651.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57651.1 - 0.0025 17.6 0.6 0.0074 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57651.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57652.1 - 2.4e-16 59.7 2.7 4.4e-16 58.9 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57652.1 - 9.4e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57653.1 - 9.6e-13 48.1 0.1 1.2e-11 44.5 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57653.1 - 1.2e-10 41.4 1.0 2.8e-10 40.3 1.0 1.6 1 0 0 1 1 1 1 Transposase 7tm_1 PF00001.21 KFM57654.1 - 1.1e-15 57.7 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 KFM57655.1 - 7.6e-69 227.4 82.4 6.5e-14 51.4 9.4 11.1 5 3 7 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 KFM57655.1 - 8.5e-30 102.3 85.4 6.7e-06 26.4 0.3 13.2 6 3 10 16 16 16 15 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM57655.1 - 9.3e-23 80.6 20.1 3.2e-06 27.1 8.4 5.2 3 1 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM57655.1 - 3.9e-16 57.1 66.2 0.073 13.7 0.1 16.6 16 2 0 16 16 16 7 Leucine Rich Repeat LRR_6 PF13516.6 KFM57655.1 - 1.1e-06 28.2 79.7 0.17 12.0 0.0 16.4 19 0 0 19 19 19 8 Leucine Rich repeat LRR_9 PF14580.6 KFM57655.1 - 6.3e-06 25.8 29.8 0.0099 15.4 0.9 5.7 2 2 3 6 6 6 5 Leucine-rich repeat DUF2857 PF11198.8 KFM57655.1 - 5.4 6.7 7.1 7.9 6.2 0.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2857) TPKR_C2 PF16920.5 KFM57655.1 - 6.6 6.9 13.8 0.15 12.2 5.1 2.9 3 0 0 3 3 3 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_8 PF13855.6 KFM57656.1 - 1.7e-28 98.1 34.9 5.1e-10 39.0 8.3 4.3 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFM57656.1 - 6.3e-16 58.2 31.8 7.6e-06 26.2 1.3 5.3 4 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM57656.1 - 5.5e-07 29.3 30.8 0.48 11.2 0.5 8.6 7 2 2 9 9 9 4 Leucine Rich Repeat LRR_5 PF13306.6 KFM57656.1 - 7.9e-07 29.1 2.6 0.0013 18.7 0.3 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) DUF3557 PF12078.8 KFM57656.1 - 0.0012 18.8 5.5 0.018 15.0 0.2 2.9 1 1 2 3 3 3 2 Domain of unknown function (DUF3557) LRR_9 PF14580.6 KFM57656.1 - 0.0043 16.6 5.9 0.25 10.8 0.9 2.7 1 1 2 3 3 3 3 Leucine-rich repeat HTH_Tnp_Tc3_2 PF01498.18 KFM57657.1 - 2.7e-16 59.6 2.2 6.4e-16 58.4 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57657.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57657.1 - 2.3e-07 30.5 1.6 5.3e-07 29.3 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57657.1 - 0.0031 17.3 0.5 0.0085 15.9 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain DUF2285 PF10074.9 KFM57657.1 - 1.2 9.8 8.5 0.091 13.4 1.6 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2285) HTH_32 PF13565.6 KFM57657.1 - 3.3 8.4 15.9 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF4371 PF14291.6 KFM57658.1 - 2.5e-07 30.6 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KFM57658.1 - 0.0038 17.1 0.1 0.0078 16.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KFM57658.1 - 0.023 14.5 0.0 0.066 13.0 0.0 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region HTH_Tnp_Tc3_2 PF01498.18 KFM57659.1 - 1.8e-16 60.1 2.4 4.5e-16 58.9 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57659.1 - 9.7e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57661.1 - 1.5e-15 57.2 6.5 1.5e-15 57.2 6.5 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57661.1 - 5.1e-05 23.1 0.1 0.008 15.9 0.0 2.6 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_32 PF13565.6 KFM57661.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 3.4 4 1 0 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57661.1 - 0.0046 16.7 0.3 0.12 12.2 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57661.1 - 0.018 15.1 0.1 0.066 13.3 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57661.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM57662.1 - 2.6e-14 53.2 1.0 4.8e-14 52.4 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57662.1 - 8.4e-14 51.5 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Sulfotransfer_1 PF00685.27 KFM57663.1 - 6.2e-44 150.5 0.0 8.4e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM57663.1 - 8.1e-08 32.9 0.0 0.00098 19.6 0.0 2.2 1 1 0 2 2 2 2 Sulfotransferase family DDE_3 PF13358.6 KFM57664.1 - 6.6e-16 58.4 0.1 7.2e-15 55.0 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57664.1 - 1.7e-15 57.0 7.8 1.7e-15 57.0 6.5 1.8 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM57664.1 - 0.00082 19.9 1.5 0.00082 19.9 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57664.1 - 0.0031 17.2 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57664.1 - 0.015 15.5 0.1 0.073 13.2 0.1 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57664.1 - 0.034 14.2 2.6 0.04 14.0 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix POT1PC PF16686.5 KFM57665.1 - 2e-22 79.8 0.3 2.5e-20 72.9 0.0 3.2 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KFM57665.1 - 1e-12 48.1 0.3 1e-12 48.1 0.3 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 KFM57665.1 - 2.6e-09 36.9 0.1 0.039 13.9 0.0 4.8 5 0 0 5 5 5 3 OB-fold nucleic acid binding domain C2 PF00168.30 KFM57666.1 - 0.0098 16.2 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 1 C2 domain hSH3 PF14603.6 KFM57668.1 - 0.00024 21.5 0.0 0.00075 19.9 0.0 1.9 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.17 KFM57668.1 - 0.0012 18.4 0.1 0.0031 17.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Histone_HNS PF00816.21 KFM57668.1 - 0.1 13.4 2.9 0.35 11.7 2.9 1.8 1 0 0 1 1 1 0 H-NS histone family TUSC2 PF15000.6 KFM57668.1 - 0.18 12.1 2.5 0.27 11.5 0.2 2.5 1 1 1 2 2 2 0 Tumour suppressor candidate 2 NINJA_B PF16136.5 KFM57668.1 - 0.65 10.4 6.5 0.19 12.1 2.4 2.3 2 0 0 2 2 2 0 Putative nuclear localisation signal zf-met PF12874.7 KFM57669.1 - 2.3e-22 78.6 14.4 4.9e-08 33.1 0.9 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM57669.1 - 4.1e-18 65.2 8.4 9.1e-07 29.0 1.5 3.7 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM57669.1 - 5.7e-07 29.8 10.5 0.097 13.0 1.2 3.4 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KFM57669.1 - 2.6e-06 27.1 1.2 0.56 10.0 0.0 3.4 3 0 0 3 3 3 2 U1 zinc finger Actin_micro PF17003.5 KFM57669.1 - 0.0001 21.6 3.6 0.39 9.8 0.2 3.0 2 1 1 3 3 3 3 Putative actin-like family zf-C2H2_4 PF13894.6 KFM57669.1 - 0.0001 22.8 7.5 0.94 10.5 0.1 3.9 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM57669.1 - 0.00018 21.2 3.8 0.0037 17.0 0.0 3.1 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-DBF PF07535.12 KFM57669.1 - 0.00032 20.7 3.4 6.2 7.0 0.1 3.7 3 0 0 3 3 3 2 DBF zinc finger AKAP95 PF04988.12 KFM57669.1 - 0.0012 19.1 6.0 0.2 11.9 0.2 3.2 3 0 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-Sec23_Sec24 PF04810.15 KFM57669.1 - 0.014 15.4 3.6 4.2 7.5 0.1 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-C2H2 PF00096.26 KFM57669.1 - 0.1 13.1 11.9 7.6 7.2 0.3 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-PHD-like PF15446.6 KFM57669.1 - 0.89 9.2 7.7 0.11 12.1 2.8 1.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain CAMSAP_CKK PF08683.11 KFM57670.1 - 1.2e-51 173.8 0.0 2.3e-51 173.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 KFM57670.1 - 7.8e-25 86.5 2.4 1.1e-24 86.1 0.5 2.1 2 0 0 2 2 2 1 CAMSAP CH domain CAMSAP_CC1 PF17095.5 KFM57670.1 - 1.8e-18 66.1 5.1 1.8e-18 66.1 5.1 3.8 2 1 1 3 3 3 1 Spectrin-binding region of Ca2+-Calmodulin CH PF00307.31 KFM57670.1 - 0.00031 20.9 0.3 0.0086 16.2 0.0 2.8 2 0 0 2 2 2 1 Calponin homology (CH) domain Ion_trans PF00520.31 KFM57672.1 - 2.6e-05 23.6 0.1 2.7e-05 23.5 0.1 1.0 1 0 0 1 1 1 1 Ion transport protein Lustrin_cystein PF14625.6 KFM57672.1 - 0.022 15.2 1.1 0.035 14.5 1.1 1.4 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Amido_AtzD_TrzD PF09663.10 KFM57673.1 - 0.045 12.8 0.4 0.05 12.6 0.4 1.1 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) DUF2618 PF10940.8 KFM57673.1 - 0.072 12.9 0.2 0.2 11.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) Tetraspanin PF00335.20 KFM57674.1 - 0.0095 15.7 5.8 0.016 15.0 5.8 1.5 1 1 0 1 1 1 1 Tetraspanin family Ion_trans PF00520.31 KFM57674.1 - 0.0098 15.1 2.8 0.019 14.2 2.8 1.5 1 0 0 1 1 1 1 Ion transport protein Na_trans_assoc PF06512.13 KFM57674.1 - 0.027 14.7 17.5 0.093 13.0 17.5 1.7 1 1 0 1 1 1 0 Sodium ion transport-associated FAD_binding_8 PF08022.12 KFM57674.1 - 0.064 13.4 1.0 0.11 12.6 1.0 1.4 1 1 0 1 1 1 0 FAD-binding domain RP-C_C PF11800.8 KFM57674.1 - 0.08 13.0 0.6 0.11 12.6 0.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region YMF19 PF02326.15 KFM57674.1 - 0.19 12.5 2.2 0.3 11.9 1.5 1.8 1 1 1 2 2 2 0 Plant ATP synthase F0 Ion_trans PF00520.31 KFM57676.1 - 6.4e-61 205.7 62.0 1.5e-37 129.1 27.0 2.1 2 0 0 2 2 2 2 Ion transport protein GPHH PF16905.5 KFM57676.1 - 5.2e-06 26.1 0.0 1.6e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KFM57676.1 - 3.9 6.1 52.8 0.54 8.9 1.8 5.2 3 1 1 4 4 4 0 Polycystin cation channel CHZ PF09649.10 KFM57677.1 - 0.0094 15.4 0.0 0.028 13.9 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone domain CHZ ATP-synt_G PF04718.15 KFM57677.1 - 6.3 7.7 6.7 66 4.4 2.8 3.2 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit HTH_28 PF13518.6 KFM57678.1 - 2.4e-07 30.8 0.2 5.9e-07 29.5 0.0 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM57678.1 - 6.3e-07 29.4 0.5 0.00015 21.8 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM57678.1 - 2.8e-06 26.9 0.4 5e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM57678.1 - 0.00032 20.3 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 KFM57678.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KFM57678.1 - 0.0012 18.7 0.1 0.0019 18.1 0.1 1.6 1 1 1 2 2 2 1 MarR family HTH_38 PF13936.6 KFM57678.1 - 0.0016 18.2 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM57678.1 - 0.0027 17.7 0.5 0.0037 17.3 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM57678.1 - 0.0055 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Tc3 transposase HTH_32 PF13565.6 KFM57678.1 - 0.013 16.1 0.5 0.024 15.3 0.5 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_5 PF01022.20 KFM57678.1 - 0.073 12.9 0.4 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.16 KFM57678.1 - 0.078 12.5 0.1 0.078 12.5 0.1 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_Tc3_2 PF01498.18 KFM57679.1 - 4.6e-16 58.8 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57679.1 - 1.3e-13 50.9 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57679.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57679.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57679.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57680.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57680.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57681.1 - 2.2e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57681.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Elicitin PF00964.17 KFM57682.1 - 0.031 14.4 2.1 0.33 11.1 0.2 2.6 1 1 2 3 3 3 0 Elicitin TPR_2 PF07719.17 KFM57683.1 - 5.1e-22 76.2 20.9 0.02 15.0 0.0 11.0 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFM57683.1 - 3.8e-21 73.9 13.0 0.18 12.7 0.2 11.0 7 2 6 13 13 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 KFM57683.1 - 4.7e-21 75.1 21.6 9.7e-06 26.0 0.2 7.1 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFM57683.1 - 3.7e-16 58.2 20.2 0.019 14.8 0.4 10.8 12 0 0 12 12 12 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM57683.1 - 3e-15 56.2 31.7 1.2e-05 25.4 0.1 7.4 4 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFM57683.1 - 1.1e-14 54.8 8.8 0.005 17.4 0.0 8.1 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM57683.1 - 3.1e-14 51.9 19.5 0.16 12.2 1.4 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM57683.1 - 3e-11 42.5 11.9 0.41 10.8 0.0 8.8 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM57683.1 - 9.4e-10 38.7 24.9 0.3 11.4 0.2 7.6 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 KFM57683.1 - 1.2e-09 38.2 18.9 0.89 10.3 0.1 10.1 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM57683.1 - 2.3e-09 36.8 11.5 0.36 10.5 1.0 9.0 8 2 2 10 10 10 2 TPR repeat TPR_17 PF13431.6 KFM57683.1 - 6.8e-07 29.2 19.5 0.082 13.3 0.6 7.8 9 1 1 10 10 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFM57683.1 - 1.1e-05 24.7 16.6 0.28 10.4 3.1 4.9 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFM57683.1 - 1.6e-05 24.6 3.2 0.58 10.1 0.1 5.2 7 0 0 7 7 4 2 Tetratricopeptide repeat ChAPs PF09295.10 KFM57683.1 - 3.7e-05 22.9 4.3 0.088 11.8 0.1 2.8 2 1 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) YfiO PF13525.6 KFM57683.1 - 0.00016 21.4 6.4 0.68 9.6 0.0 5.1 5 1 0 6 6 6 1 Outer membrane lipoprotein TPR_21 PF09976.9 KFM57683.1 - 0.00089 19.0 8.1 0.002 17.9 2.5 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 KFM57683.1 - 0.00095 19.5 4.1 0.42 11.0 0.3 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF410 PF04190.13 KFM57683.1 - 0.0062 16.4 1.7 0.014 15.2 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF410) Prefoldin PF02996.17 KFM57683.1 - 0.0084 16.0 0.2 0.11 12.4 0.0 2.9 2 0 0 2 2 2 1 Prefoldin subunit ATP13 PF12921.7 KFM57683.1 - 0.0088 15.9 0.1 0.12 12.2 0.0 2.7 3 0 0 3 3 3 1 Mitochondrial ATPase expression Ferritin PF00210.24 KFM57683.1 - 0.015 15.2 1.1 0.38 10.7 0.2 2.8 3 0 0 3 3 2 0 Ferritin-like domain HrpB1_HrpK PF09613.10 KFM57683.1 - 0.025 14.2 1.4 1.2 8.8 0.1 3.4 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Ub-Mut7C PF14451.6 KFM57683.1 - 0.15 11.9 0.5 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Mut7-C ubiquitin Fis1_TPR_C PF14853.6 KFM57683.1 - 1.5 9.0 0.0 1.5 9.0 0.0 5.0 7 0 0 7 7 4 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 KFM57683.1 - 4.9 6.8 8.9 12 5.6 0.1 4.1 2 2 1 3 3 3 0 26S proteasome subunit RPN7 Allatostatin PF05953.12 KFM57685.1 - 2.6e-19 66.8 89.9 1.7 9.5 0.1 17.8 18 0 0 18 18 18 16 Allatostatin PagP PF07017.11 KFM57685.1 - 0.16 11.4 5.2 14 5.1 0.0 5.5 3 2 5 8 8 8 0 Antimicrobial peptide resistance and lipid A acylation protein PagP zf-RanBP PF00641.18 KFM57686.1 - 3.5e-06 26.2 14.8 0.001 18.3 4.8 2.8 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KFM57686.1 - 0.0021 18.0 20.3 0.0046 17.0 10.7 2.8 2 1 1 3 3 3 2 Double zinc ribbon DUF1192 PF06698.11 KFM57688.1 - 0.0024 17.9 0.3 2.6 8.2 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1192) BCAS2 PF05700.11 KFM57688.1 - 0.32 10.7 25.1 0.12 12.0 9.0 2.2 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) FRQ PF09421.10 KFM57688.1 - 1.7 6.5 4.8 1.2 7.0 2.9 1.7 1 1 1 2 2 2 0 Frequency clock protein GAS PF13851.6 KFM57689.1 - 0.00015 21.1 20.0 0.0003 20.2 19.9 1.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 KFM57689.1 - 0.0032 17.3 8.8 0.28 11.1 0.5 2.8 1 1 1 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor ADIP PF11559.8 KFM57689.1 - 0.0036 17.4 14.6 0.28 11.3 4.6 2.4 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding DMPK_coil PF08826.10 KFM57689.1 - 0.0038 17.3 0.9 0.0038 17.3 0.9 3.1 2 2 0 3 3 3 1 DMPK coiled coil domain like Dynamitin PF04912.14 KFM57689.1 - 0.042 13.2 11.0 0.056 12.8 11.0 1.2 1 0 0 1 1 1 0 Dynamitin Prefoldin_2 PF01920.20 KFM57689.1 - 0.057 13.4 16.0 0.047 13.7 5.9 2.6 2 1 0 2 2 2 0 Prefoldin subunit SlyX PF04102.12 KFM57689.1 - 0.058 14.0 4.1 2.7 8.7 0.0 3.1 2 1 1 3 3 3 0 SlyX APG6_N PF17675.1 KFM57689.1 - 0.073 13.6 14.7 0.27 11.8 1.3 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1843 PF08898.10 KFM57689.1 - 0.14 12.7 2.3 0.54 10.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) TPR_MLP1_2 PF07926.12 KFM57689.1 - 0.15 12.2 14.9 0.12 12.4 8.6 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 KFM57689.1 - 0.17 12.3 23.9 0.27 11.7 7.9 3.1 2 1 0 2 2 2 0 Cell division protein ZapB ASL_C PF08328.11 KFM57689.1 - 0.23 11.6 5.3 2 8.5 0.5 2.8 2 2 0 2 2 2 0 Adenylosuccinate lyase C-terminal Cep57_MT_bd PF06657.13 KFM57689.1 - 0.45 11.0 8.0 5.5 7.5 0.5 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Leu_zip PF15294.6 KFM57689.1 - 0.47 9.9 20.3 0.18 11.3 7.3 2.0 1 1 1 2 2 2 0 Leucine zipper TMF_TATA_bd PF12325.8 KFM57689.1 - 0.5 10.6 19.5 0.21 11.8 7.2 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding JIP_LZII PF16471.5 KFM57689.1 - 0.58 10.4 13.6 0.5 10.6 2.6 2.8 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II OmpH PF03938.14 KFM57689.1 - 0.68 10.3 10.0 1.8 8.9 10.0 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PP2C_C PF07830.13 KFM57689.1 - 0.9 10.0 6.2 0.66 10.5 2.6 2.4 2 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Fungal_TACC PF12709.7 KFM57689.1 - 1.1 9.8 16.3 1.2 9.6 3.7 2.6 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins JHD PF17811.1 KFM57689.1 - 1.1 9.8 9.9 0.12 12.9 3.4 2.2 2 1 0 2 2 2 0 Jumonji helical domain Uso1_p115_C PF04871.13 KFM57689.1 - 2.4 8.5 17.2 1.2 9.5 5.7 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Rho_Binding PF08912.11 KFM57689.1 - 3.4 8.5 18.4 0.19 12.6 6.4 3.0 1 1 2 3 3 3 0 Rho Binding bZIP_1 PF00170.21 KFM57689.1 - 3.8 7.7 20.8 2 8.5 1.1 3.3 2 1 2 4 4 4 0 bZIP transcription factor YabA PF06156.13 KFM57689.1 - 4.4 8.0 19.2 0.44 11.2 6.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 KFM57689.1 - 5 7.3 12.1 4.8 7.3 2.8 3.2 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 betaPIX_CC PF16523.5 KFM57689.1 - 7.4 6.5 13.0 6.5 6.7 2.6 2.6 1 1 1 2 2 2 0 betaPIX coiled coil Cnn_1N PF07989.11 KFM57689.1 - 8 6.7 17.8 7 6.9 5.5 2.9 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 HTH_Tnp_Tc3_2 PF01498.18 KFM57691.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57691.1 - 9.4e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CLASP_N PF12348.8 KFM57692.1 - 1e-20 74.3 0.0 1.3e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal HEAT_EZ PF13513.6 KFM57692.1 - 1e-07 32.3 0.1 0.00055 20.4 0.1 3.1 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KFM57692.1 - 1.7e-07 30.9 0.0 1.4e-05 24.9 0.0 3.5 4 0 0 4 4 3 1 HEAT repeat Cnd1 PF12717.7 KFM57692.1 - 1.5e-06 28.4 1.2 0.0075 16.3 0.1 2.5 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFM57692.1 - 0.00019 20.1 0.1 0.00065 18.4 0.0 1.7 1 1 1 2 2 2 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KFM57692.1 - 0.00023 21.7 0.0 0.98 10.1 0.0 2.6 1 1 2 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KFM57692.1 - 0.00029 21.2 0.0 0.0036 17.6 0.0 2.4 1 1 0 2 2 2 1 HEAT repeats Sec7_N PF12783.7 KFM57692.1 - 0.0017 18.2 0.0 0.61 10.0 0.0 2.4 1 1 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Tti2 PF10521.9 KFM57692.1 - 0.0028 17.3 0.1 0.0088 15.6 0.1 1.7 1 1 0 1 1 1 1 Tti2 family HMW1C_N PF18071.1 KFM57692.1 - 0.003 17.3 0.1 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 HMW1C N-terminal DRIM PF07539.12 KFM57692.1 - 0.042 12.2 0.2 0.48 8.7 0.1 1.9 1 1 0 1 1 1 0 Down-regulated in metastasis Arm PF00514.23 KFM57692.1 - 0.12 12.5 0.3 0.54 10.4 0.1 2.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KFM57693.1 - 1.2e-40 139.4 2.3 8e-38 130.3 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KFM57693.1 - 0.00064 19.8 0.0 1.3 9.5 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat TIP120 PF08623.10 KFM57693.1 - 0.013 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) TAN PF11640.8 KFM57693.1 - 0.079 13.1 1.1 0.48 10.5 0.1 2.9 3 1 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Ipi1_N PF12333.8 KFM57693.1 - 0.57 10.8 4.1 1.4 9.5 0.2 3.1 2 2 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 KFM57694.1 - 3.3e-05 23.8 0.1 0.16 12.3 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat Adaptin_N PF01602.20 KFM57694.1 - 5e-05 22.1 5.4 0.041 12.5 0.0 2.3 1 1 1 2 2 2 2 Adaptin N terminal region ParcG PF10274.9 KFM57694.1 - 8.8e-05 22.7 4.2 0.00018 21.7 0.7 2.4 1 1 0 2 2 2 1 Parkin co-regulated protein RTP1_C1 PF10363.9 KFM57694.1 - 0.00011 22.4 3.5 0.11 12.6 0.2 2.8 2 1 1 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 TPR_20 PF14561.6 KFM57694.1 - 0.0005 20.3 1.0 0.71 10.2 0.2 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat HEAT_2 PF13646.6 KFM57694.1 - 0.0014 19.0 0.3 0.084 13.3 0.0 2.6 1 1 3 4 4 4 2 HEAT repeats Telomere_reg-2 PF10193.9 KFM57694.1 - 0.0052 17.2 5.6 0.019 15.4 2.0 2.7 1 1 2 3 3 3 1 Telomere length regulation protein Vac14_Fab1_bd PF12755.7 KFM57694.1 - 0.0057 17.2 1.1 0.32 11.6 0.5 2.3 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region DUF4042 PF13251.6 KFM57694.1 - 0.006 16.3 2.4 0.11 12.2 0.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4042) UME PF08064.13 KFM57694.1 - 0.0099 15.8 2.3 2.1 8.3 0.4 3.3 2 1 1 3 3 3 1 UME (NUC010) domain MMS19_C PF12460.8 KFM57694.1 - 0.02 14.0 3.5 0.027 13.6 0.3 2.2 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 KFM57694.1 - 0.025 15.1 0.1 1.6 9.4 0.0 2.6 2 0 0 2 2 2 0 HEAT-like repeat Lsm_interact PF05391.11 KFM57694.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Lsm interaction motif FANCI_S2 PF14676.6 KFM57694.1 - 0.066 13.5 3.3 0.24 11.7 1.4 2.6 1 1 1 2 2 2 0 FANCI solenoid 2 V-ATPase_H_C PF11698.8 KFM57694.1 - 0.091 12.9 3.6 0.18 11.9 0.9 2.4 2 0 0 2 2 2 0 V-ATPase subunit H Cohesin_HEAT PF12765.7 KFM57694.1 - 0.21 11.9 1.1 0.76 10.1 0.6 2.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion IFRD PF05004.13 KFM57694.1 - 4.2 6.4 11.3 0.46 9.5 3.5 2.8 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HTH_Tnp_Tc3_2 PF01498.18 KFM57695.1 - 4.1e-16 59.0 3.4 5.2e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57695.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57695.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57695.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain SSDP PF04503.13 KFM57697.1 - 4.4e-84 283.2 84.1 5.8e-84 282.8 84.1 1.1 1 0 0 1 1 1 1 Single-stranded DNA binding protein, SSDP 7tm_1 PF00001.21 KFM57699.1 - 7.3e-10 38.6 2.1 8.2e-10 38.4 2.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM57699.1 - 0.0015 18.2 2.4 0.0015 18.2 2.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFM57699.1 - 0.0015 17.9 1.6 0.0016 17.9 1.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFM57699.1 - 0.034 13.9 0.7 0.035 13.8 0.7 1.0 1 0 0 1 1 1 0 Olfactory receptor FtsL PF04999.13 KFM57699.1 - 0.1 12.6 0.2 0.11 12.5 0.2 1.1 1 0 0 1 1 1 0 Cell division protein FtsL DDE_3 PF13358.6 KFM57700.1 - 1.5e-16 60.5 0.1 1.3e-15 57.4 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57700.1 - 1.3e-10 41.4 1.0 2.5e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM57701.1 - 2.7e-16 59.6 2.2 4.9e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57701.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.22 KFM57702.1 - 7.3e-15 54.5 0.2 1.1e-14 53.9 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM57702.1 - 0.00052 20.1 0.1 0.0015 18.6 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_Rrp7 PF17799.1 KFM57702.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain F-box-like PF12937.7 KFM57703.1 - 1.3e-09 37.8 0.7 1.4e-09 37.6 0.7 1.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM57703.1 - 3e-08 33.3 0.5 3.3e-08 33.2 0.5 1.1 1 0 0 1 1 1 1 F-box domain YjhX_toxin PF09857.9 KFM57704.1 - 0.043 13.8 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative toxin of bacterial toxin-antitoxin pair zf-CCHC_2 PF13696.6 KFM57704.1 - 2.4 8.1 6.8 0.34 10.8 1.6 2.3 2 1 0 2 2 2 0 Zinc knuckle TK PF00265.18 KFM57705.1 - 2e-66 223.2 0.3 2.3e-66 223.0 0.3 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 KFM57705.1 - 0.00034 20.6 0.0 0.00049 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFM57705.1 - 0.05 13.5 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Glyco_hydro_47 PF01532.20 KFM57706.1 - 1.8e-152 508.4 0.1 2.2e-152 508.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 KFM57706.1 - 0.0062 15.6 0.0 0.25 10.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 HEXIM PF15313.6 KFM57707.1 - 4.5e-21 75.5 0.7 4.5e-21 75.5 0.7 4.0 2 2 2 4 4 4 2 Hexamethylene bis-acetamide-inducible protein CCER1 PF15482.6 KFM57707.1 - 0.015 15.2 1.5 0.031 14.2 1.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 PhoU PF01895.19 KFM57707.1 - 0.45 11.0 5.5 3.2 8.3 4.8 2.4 1 1 0 1 1 1 0 PhoU domain GvpL_GvpF PF06386.11 KFM57707.1 - 5.5 6.8 8.1 0.44 10.4 2.5 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Cnn_1N PF07989.11 KFM57707.1 - 7.6 6.8 14.0 3.8 7.7 3.1 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 HTH_32 PF13565.6 KFM57710.1 - 9.9e-08 32.5 0.7 2.2e-07 31.4 0.2 1.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57710.1 - 0.015 15.5 0.3 0.031 14.5 0.3 1.5 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.6 KFM57710.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 KFM57710.1 - 0.034 14.3 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain SpoIIID PF12116.8 KFM57710.1 - 0.093 12.8 0.1 0.19 11.9 0.1 1.6 2 0 0 2 2 2 0 Stage III sporulation protein D FKBP_C PF00254.28 KFM57712.1 - 5.3e-23 81.1 0.0 1.1e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KFM57712.1 - 6.4e-17 62.0 0.0 6.4e-17 62.0 0.0 3.1 2 1 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 KFM57712.1 - 0.0012 19.4 0.0 0.004 17.6 0.0 2.0 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain CENP-F_N PF10481.9 KFM57714.1 - 0.13 11.9 0.3 0.17 11.5 0.3 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain BPL_LplA_LipB PF03099.19 KFM57715.1 - 4.8e-22 78.3 0.0 8.4e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.9 KFM57715.1 - 6.1e-09 35.4 0.8 9.7e-05 21.6 0.2 2.2 1 1 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_C PF02237.17 KFM57715.1 - 7.5e-05 22.5 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DUF4314 PF14192.6 KFM57715.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) Glyco_hydro_42M PF08532.10 KFM57715.1 - 0.068 12.7 0.0 0.34 10.4 0.0 2.0 1 1 0 1 1 1 0 Beta-galactosidase trimerisation domain MADF_DNA_bdg PF10545.9 KFM57716.1 - 8.9e-08 32.4 0.1 9.8e-08 32.2 0.1 1.0 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 KFM57716.1 - 0.078 13.1 0.1 0.09 12.9 0.1 1.0 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Spidroin_N PF16763.5 KFM57717.1 - 8.7e-45 151.8 4.1 1.6e-44 150.9 4.1 1.4 1 0 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term Na_H_Exchanger PF00999.21 KFM57719.1 - 1.1e-12 47.5 9.1 1.2e-12 47.4 9.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RseC_MucC PF04246.12 KFM57719.1 - 1.5 8.7 3.6 0.57 10.1 0.9 1.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Abhydrolase_1 PF00561.20 KFM57720.1 - 4e-23 82.4 0.1 1.8e-21 77.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM57720.1 - 9e-17 62.4 0.0 1.2e-16 62.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM57720.1 - 3.5e-14 52.6 0.0 5.2e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFM57720.1 - 0.0025 16.6 0.0 0.0057 15.4 0.0 1.5 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 KFM57720.1 - 0.0037 17.0 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 KFM57720.1 - 0.0037 15.8 0.0 0.053 12.0 0.0 2.0 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Thioesterase PF00975.20 KFM57720.1 - 0.022 14.9 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain DUF915 PF06028.11 KFM57720.1 - 0.026 13.9 0.0 0.24 10.7 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KFM57720.1 - 0.029 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KFM57720.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KFM57720.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) HTH_Tnp_Tc3_2 PF01498.18 KFM57721.1 - 2.2e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57721.1 - 9.5e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57722.1 - 4.9e-16 58.7 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57722.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57722.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57722.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57722.1 - 3.2 8.4 16.9 0.12 13.0 1.9 3.5 3 1 1 4 4 4 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM57723.1 - 3.1e-16 59.4 3.2 4e-16 59.0 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57723.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57725.1 - 7.3e-16 58.2 0.0 1.7e-15 57.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM57726.1 - 5.3e-10 39.2 0.0 8.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KFM57726.1 - 0.00026 20.7 0.0 0.00087 19.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease COQ7 PF03232.13 KFM57727.1 - 1.4e-24 86.8 0.0 1.6e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 THP2 PF09432.10 KFM57727.1 - 0.0097 16.0 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Tho complex subunit THP2 RNase_E_G PF10150.9 KFM57727.1 - 0.024 14.1 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family Ribonuc_2-5A PF06479.12 KFM57727.1 - 0.041 14.1 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease 2-5A Helicase_C PF00271.31 KFM57728.1 - 8.4e-24 84.1 0.2 1.6e-23 83.1 0.2 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain VWA PF00092.28 KFM57728.1 - 0.0057 16.9 0.2 0.0085 16.4 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain NB-ARC PF00931.22 KFM57728.1 - 0.02 14.1 0.1 3.3 6.8 0.2 2.1 2 0 0 2 2 2 0 NB-ARC domain ERCC3_RAD25_C PF16203.5 KFM57728.1 - 0.048 12.9 0.1 0.078 12.2 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KFM57729.1 - 4.8e-17 62.3 0.0 7.1e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM57729.1 - 0.073 13.1 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CAP PF00188.26 KFM57730.1 - 1e-16 61.9 0.0 1.7e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Nbas_N PF15492.6 KFM57730.1 - 0.078 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Glyco_hydro_18 PF00704.28 KFM57731.1 - 8e-96 321.4 0.2 9.5e-96 321.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 KFM57731.1 - 0.0076 16.4 1.7 0.014 15.5 1.7 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Glyco_hydro_114 PF03537.13 KFM57731.1 - 0.18 11.1 0.3 1.1 8.5 0.3 2.1 1 1 0 1 1 1 0 Glycoside-hydrolase family GH114 CRAL_TRIO_N PF03765.15 KFM57732.1 - 0.0042 17.2 0.2 0.0068 16.6 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 KFM57733.1 - 1.1e-23 83.8 0.2 1.4e-23 83.4 0.2 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM57733.1 - 2.8e-06 27.6 0.0 3.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Peptidase_M1 PF01433.20 KFM57734.1 - 2.7e-46 157.9 0.1 4.2e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFM57734.1 - 4e-35 120.3 0.1 7.4e-35 119.5 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFM57734.1 - 2.9e-25 89.5 0.1 4.1e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KFM57734.1 - 0.19 12.1 2.4 2.8 8.4 0.4 3.3 3 1 0 3 3 3 0 M61 glycyl aminopeptidase TryThrA_C PF12319.8 KFM57734.1 - 0.22 11.0 1.9 0.72 9.3 1.6 1.9 1 1 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal HSP90 PF00183.18 KFM57735.1 - 1.2e-224 747.0 20.7 1.9e-224 746.4 20.7 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFM57735.1 - 1.1e-13 51.7 0.1 2e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFM57735.1 - 4.7e-11 42.7 0.2 1.3e-10 41.2 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4023 PF13215.6 KFM57735.1 - 0.24 11.5 3.4 3.8 7.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4023) YqfQ PF14181.6 KFM57735.1 - 3.1 8.0 4.4 3.2 7.9 2.5 2.0 2 0 0 2 2 2 0 YqfQ-like protein DUF4413 PF14372.6 KFM57735.1 - 7.1 7.1 6.3 1.8 8.9 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) Ribosomal_S19e PF01090.19 KFM57736.1 - 4.1e-42 143.1 0.2 4.5e-42 143.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Dynein_attach_N PF15867.5 KFM57737.1 - 1.7e-20 72.8 0.0 2.5e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Dynein attachment factor N-terminus DUF4745 PF15923.5 KFM57738.1 - 0.046 13.7 0.2 0.072 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) Peptidase_M76 PF09768.9 KFM57740.1 - 8.8e-46 155.8 6.0 1.1e-45 155.5 6.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family BSP PF04450.12 KFM57740.1 - 0.026 14.3 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase of plants and bacteria SprT-like PF10263.9 KFM57740.1 - 0.067 13.1 0.3 0.14 12.0 0.3 1.6 1 1 0 1 1 1 0 SprT-like family Thioredoxin PF00085.20 KFM57741.1 - 1.8e-20 72.8 0.1 2.3e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFM57741.1 - 0.00025 21.3 0.1 0.0024 18.2 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like ERp29_N PF07912.13 KFM57741.1 - 0.0057 16.8 0.0 0.0082 16.3 0.0 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_2 PF13098.6 KFM57741.1 - 0.012 16.1 0.2 0.024 15.1 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFM57741.1 - 0.11 12.7 0.6 0.22 11.7 0.6 1.5 1 1 0 1 1 1 0 Thioredoxin-like Evr1_Alr PF04777.13 KFM57742.1 - 7.6e-26 90.5 0.7 2e-25 89.2 0.5 1.8 2 0 0 2 2 2 1 Erv1 / Alr family FAD_SOX PF18371.1 KFM57742.1 - 7.7e-22 77.6 0.0 2.2e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase eIF-5_eIF-2B PF01873.17 KFM57742.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain found in IF2B/IF5 SH3_2 PF07653.17 KFM57745.1 - 2.8e-22 78.2 0.0 2.3e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KFM57745.1 - 9.5e-19 67.0 4.0 6.9e-10 38.6 0.2 3.6 3 2 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KFM57745.1 - 4.6e-12 45.3 1.3 6.5e-06 25.7 0.1 3.2 2 2 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 KFM57746.1 - 0.03 14.1 0.2 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein fn3 PF00041.21 KFM57746.1 - 0.061 13.7 0.0 0.089 13.2 0.0 1.3 1 0 0 1 1 1 0 Fibronectin type III domain Filament PF00038.21 KFM57748.1 - 0.0042 16.7 8.9 0.0048 16.5 8.9 1.1 1 0 0 1 1 1 1 Intermediate filament protein Vps5 PF09325.10 KFM57748.1 - 0.011 15.2 8.6 0.014 15.0 8.6 1.3 1 0 0 1 1 1 0 Vps5 C terminal like OmpH PF03938.14 KFM57748.1 - 0.014 15.8 10.8 0.016 15.5 10.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ACCA PF03255.14 KFM57748.1 - 0.021 14.7 3.3 0.025 14.5 3.3 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GAS PF13851.6 KFM57748.1 - 0.025 13.9 12.5 0.035 13.4 12.5 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 KFM57748.1 - 0.028 14.7 14.1 0.033 14.4 14.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 KFM57748.1 - 0.042 13.9 8.6 0.056 13.6 8.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UvrD_C PF13361.6 KFM57748.1 - 0.061 12.7 6.3 0.067 12.6 6.3 1.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain BRI3BP PF14965.6 KFM57748.1 - 0.063 12.8 0.5 0.077 12.5 0.5 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 PHM7_cyt PF14703.6 KFM57748.1 - 0.074 13.3 5.7 0.082 13.1 5.7 1.1 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter BCAS2 PF05700.11 KFM57748.1 - 0.078 12.7 9.9 0.067 12.9 8.9 1.3 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) HAP1_N PF04849.13 KFM57748.1 - 0.16 11.1 13.1 1.2 8.3 13.1 1.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Mei5 PF10376.9 KFM57748.1 - 0.19 11.6 8.9 0.24 11.2 8.9 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein DASH_Dam1 PF08653.10 KFM57748.1 - 0.19 11.5 1.1 17 5.3 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF1664 PF07889.12 KFM57748.1 - 0.25 11.4 4.1 0.28 11.2 3.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RRP36 PF06102.12 KFM57748.1 - 0.36 10.8 10.6 0.5 10.3 10.6 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 H-kinase_dim PF02895.14 KFM57748.1 - 0.4 11.1 3.2 0.41 11.1 1.9 1.8 2 1 0 2 2 1 0 Signal transducing histidine kinase, homodimeric domain Com_YlbF PF06133.11 KFM57748.1 - 0.6 10.7 9.9 0.78 10.4 9.9 1.3 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA FlxA PF14282.6 KFM57748.1 - 0.62 10.1 8.6 1.4 9.0 8.7 1.6 1 1 0 1 1 1 0 FlxA-like protein FCH PF00611.23 KFM57748.1 - 1.2 9.5 10.9 2.9 8.2 10.8 1.6 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain TRAF_BIRC3_bd PF16673.5 KFM57748.1 - 1.3 8.8 8.4 1.4 8.7 5.8 2.4 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain LRS4 PF10422.9 KFM57748.1 - 1.4 8.5 9.1 1.5 8.4 9.1 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 FemAB PF02388.16 KFM57748.1 - 2.6 6.8 7.7 3 6.6 7.7 1.1 1 0 0 1 1 1 0 FemAB family TMPIT PF07851.13 KFM57748.1 - 3.3 6.9 9.0 3.6 6.7 9.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein ZapB PF06005.12 KFM57748.1 - 6.3 7.3 14.0 13 6.4 6.0 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Med9 PF07544.13 KFM57749.1 - 0.0039 17.3 5.4 0.0046 17.0 5.4 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF406 PF04175.12 KFM57749.1 - 0.059 13.9 0.5 0.069 13.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF406) Iron_permease PF04120.12 KFM57749.1 - 0.062 13.1 2.2 0.067 13.0 2.2 1.1 1 0 0 1 1 1 0 Low affinity iron permease BppU_N PF10651.9 KFM57749.1 - 0.13 12.0 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 BppU N-terminal domain DUF4349 PF14257.6 KFM57749.1 - 0.89 9.0 6.6 1 8.8 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DivIC PF04977.15 KFM57749.1 - 3 7.7 10.9 1.4 8.8 6.0 2.0 1 1 1 2 2 2 0 Septum formation initiator TP6A_N PF04406.14 KFM57750.1 - 1.3 9.1 5.7 0.2 11.7 1.6 1.8 2 1 1 3 3 3 0 Type IIB DNA topoisomerase HTH_Tnp_Tc3_2 PF01498.18 KFM57751.1 - 1.1e-17 64.1 1.4 2.1e-17 63.1 1.4 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57751.1 - 1.1e-06 29.2 9.3 2.8e-06 27.8 2.3 2.7 3 0 0 3 3 3 1 Homeodomain-like domain DDE_3 PF13358.6 KFM57751.1 - 1.9e-05 24.5 0.8 0.017 14.9 0.2 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease MarR_2 PF12802.7 KFM57751.1 - 0.00033 20.5 0.5 0.039 13.8 0.0 2.7 2 0 0 2 2 2 1 MarR family HTH_3 PF01381.22 KFM57751.1 - 0.00045 20.2 1.9 0.02 14.9 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix PAX PF00292.18 KFM57751.1 - 0.00099 19.0 0.0 0.0016 18.3 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_Crp_2 PF13545.6 KFM57751.1 - 0.0034 17.3 1.9 0.014 15.3 0.1 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM57751.1 - 0.0054 16.8 2.2 0.1 12.8 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 KFM57751.1 - 0.023 14.3 1.6 0.48 10.0 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM57751.1 - 0.043 13.6 4.5 0.14 12.0 0.1 2.8 3 0 0 3 3 3 0 Homeodomain-like domain HTH_26 PF13443.6 KFM57751.1 - 0.15 12.6 0.4 10 6.6 0.2 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain DDE_3 PF13358.6 KFM57752.1 - 4.8e-16 58.8 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57752.1 - 7.7e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57752.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57752.1 - 0.0024 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57752.1 - 0.015 15.4 0.1 0.063 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57752.1 - 0.034 14.2 0.4 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix UDG PF03167.19 KFM57753.1 - 3.1e-23 82.5 0.0 6.2e-23 81.5 0.0 1.5 1 1 1 2 2 2 1 Uracil DNA glycosylase superfamily Cupin_8 PF13621.6 KFM57754.1 - 1.9e-37 129.4 4.4 2.3e-37 129.1 4.4 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFM57754.1 - 0.00068 19.2 0.0 0.00095 18.7 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFM57754.1 - 0.00093 19.6 0.2 0.0017 18.8 0.1 1.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase ABC_membrane PF00664.23 KFM57755.1 - 1.6e-66 224.7 5.3 2e-66 224.4 5.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFM57755.1 - 3.1e-10 40.7 0.1 8.1e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KFM57755.1 - 0.0013 19.2 0.2 0.0042 17.5 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFM57755.1 - 0.0027 17.6 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KFM57755.1 - 0.0077 16.2 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 KFM57755.1 - 0.0082 15.9 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KFM57755.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 KFM57755.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFM57755.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KFM57755.1 - 0.049 13.6 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KFM57755.1 - 0.055 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFM57755.1 - 0.098 13.2 0.1 0.26 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 KFM57755.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_15 PF13175.6 KFM57755.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.23 KFM57756.1 - 3.1e-58 197.2 1.0 6e-58 196.2 1.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM57756.1 - 1.4e-14 54.3 0.1 8.4e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM57756.1 - 2.5e-07 30.9 1.0 6.2e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFM57756.1 - 0.021 14.5 0.1 0.17 11.5 0.1 2.3 1 1 0 1 1 1 0 SWI2/SNF2 ATPase DUF3452 PF11934.8 KFM57756.1 - 0.096 12.2 0.5 0.27 10.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) ADD_ATRX PF17981.1 KFM57757.1 - 2.1e-14 53.1 2.8 7e-14 51.4 2.8 1.9 1 0 0 1 1 1 1 Cysteine Rich ADD domain FCH PF00611.23 KFM57757.1 - 0.053 13.8 0.4 0.053 13.8 0.4 2.5 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain SR1P PF13790.6 KFM57757.1 - 0.18 11.9 4.8 1.1 9.4 0.4 2.9 2 0 0 2 2 2 0 SR1 protein PHD PF00628.29 KFM57757.1 - 3.7 7.5 19.5 0.04 13.8 7.9 3.0 2 1 1 3 3 3 0 PHD-finger zf-H2C2_2 PF13465.6 KFM57759.1 - 5.1e-61 200.5 70.3 7.4e-10 38.8 0.4 10.2 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57759.1 - 1.8e-46 154.0 81.1 2.3e-06 27.7 0.9 9.2 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57759.1 - 1.1e-38 128.5 72.3 0.00021 21.9 0.8 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM57759.1 - 3e-19 68.7 63.6 0.012 16.0 0.9 9.5 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM57759.1 - 2e-18 65.9 66.7 0.018 15.0 0.2 10.0 9 3 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM57759.1 - 5.2e-17 61.7 54.5 0.0024 18.1 0.2 9.5 8 1 1 9 9 9 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM57759.1 - 1.1e-13 51.2 15.6 0.0026 18.0 0.7 6.6 1 1 6 7 7 7 3 BolA-like protein zf-H2C2_5 PF13909.6 KFM57759.1 - 1.7e-11 43.6 49.7 0.11 12.2 0.0 9.9 9 1 1 10 10 10 6 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM57759.1 - 3.1e-08 33.2 49.1 0.21 11.4 0.3 8.9 9 0 0 9 9 9 7 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFM57759.1 - 8.8e-06 26.0 58.1 0.84 10.0 15.1 8.2 1 1 6 7 7 7 3 C2H2 type zinc-finger (2 copies) TRAF6_Z2 PF18048.1 KFM57759.1 - 6.4e-05 23.0 41.7 0.052 13.6 1.1 8.5 9 0 0 9 9 9 3 TNF receptor-associated factor 6 zinc finger 2 zf-C2HC_2 PF13913.6 KFM57759.1 - 0.00013 21.7 37.4 1.4 8.9 0.2 8.8 9 0 0 9 9 8 3 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM57759.1 - 0.00039 20.5 25.7 0.77 9.9 0.5 8.5 9 0 0 9 9 9 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_11 PF17123.5 KFM57759.1 - 0.0014 18.4 15.2 12 5.8 0.1 7.6 8 0 0 8 8 8 0 RING-like zinc finger Rad50_zn_hook PF04423.14 KFM57759.1 - 0.0025 17.6 12.6 0.24 11.3 0.4 4.2 3 2 2 5 5 4 2 Rad50 zinc hook motif BHD_1 PF10403.9 KFM57759.1 - 0.0042 16.9 1.1 15 5.5 0.1 4.3 3 1 0 3 3 3 0 Rad4 beta-hairpin domain 1 zf-C2H2_9 PF16293.5 KFM57759.1 - 0.0095 15.8 32.3 2.3 8.1 0.2 8.5 1 1 8 9 9 9 1 C2H2 type zinc-finger (1 copy) Baculo_IE-1 PF05290.11 KFM57759.1 - 0.012 15.5 24.4 4.9 7.1 0.6 6.7 1 1 5 6 6 6 0 Baculovirus immediate-early protein (IE-0) zf-FPG_IleRS PF06827.14 KFM57759.1 - 0.027 14.3 11.8 1.8 8.5 0.1 4.8 5 0 0 5 5 4 0 Zinc finger found in FPG and IleRS FYVE PF01363.21 KFM57759.1 - 0.078 13.1 47.2 1.6 8.9 7.7 6.1 1 1 4 5 5 5 0 FYVE zinc finger Complex1_49kDa PF00346.19 KFM57759.1 - 0.14 11.2 0.3 13 4.8 0.0 2.4 1 1 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-Paramyx-P PF13008.7 KFM57759.1 - 0.24 10.9 0.1 0.24 10.9 0.1 4.3 5 1 0 5 5 5 0 Zinc-binding domain of Paramyxoviridae V protein GAGA PF09237.11 KFM57759.1 - 0.72 9.7 18.6 29 4.6 0.4 7.0 2 2 6 8 8 8 0 GAGA factor Zn-C2H2_12 PF18112.1 KFM57759.1 - 1.3 9.6 39.4 0.26 11.8 0.7 8.9 9 0 0 9 9 9 0 Autophagy receptor zinc finger-C2H2 domain PHF5 PF03660.14 KFM57759.1 - 1.9 8.7 27.9 11 6.3 0.8 5.3 1 1 5 6 6 6 0 PHF5-like protein zf-Dof PF02701.15 KFM57759.1 - 7.7 6.8 18.8 3 8.1 0.3 5.0 2 1 2 5 5 5 0 Dof domain, zinc finger LIM PF00412.22 KFM57763.1 - 8.8e-09 35.5 2.4 1.1e-08 35.1 2.4 1.1 1 0 0 1 1 1 1 LIM domain Ribosomal_L37e PF01907.19 KFM57763.1 - 0.016 15.4 6.2 0.3 11.3 0.5 2.2 1 1 1 2 2 2 0 Ribosomal protein L37e zf-trcl PF13451.6 KFM57763.1 - 0.052 13.5 2.1 5.6 6.9 0.1 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain LIM PF00412.22 KFM57764.1 - 3.2e-13 49.7 7.7 4.8e-13 49.1 7.7 1.3 1 0 0 1 1 1 1 LIM domain HTH_Tnp_Tc3_2 PF01498.18 KFM57765.1 - 3.1e-19 69.0 3.8 5.8e-19 68.1 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57765.1 - 5.3e-16 58.7 0.0 2.3e-15 56.6 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM57765.1 - 3.7e-07 30.7 2.0 3.7e-07 30.7 2.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM57765.1 - 0.00038 20.3 0.5 0.0057 16.5 0.0 2.5 2 1 1 3 3 3 1 MarR family HTH_29 PF13551.6 KFM57765.1 - 0.0013 18.7 0.3 0.023 14.7 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM57765.1 - 0.0015 18.6 0.8 0.32 11.2 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM57765.1 - 0.0017 18.3 0.3 0.021 14.8 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_7 PF02796.15 KFM57765.1 - 0.029 14.4 0.2 9.4 6.4 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM57765.1 - 0.03 14.1 1.6 1.3 8.9 0.0 2.9 2 1 0 2 2 2 0 Homeodomain-like domain Pkinase PF00069.25 KFM57768.1 - 0.0051 16.2 0.0 0.0054 16.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain HTH_Tnp_Tc3_2 PF01498.18 KFM57771.1 - 2.4e-15 56.5 0.9 4.9e-15 55.5 0.9 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57771.1 - 2.5e-11 43.5 0.0 4.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MarR_2 PF12802.7 KFM57771.1 - 0.0037 17.1 0.4 0.16 11.9 0.0 2.4 1 1 1 2 2 2 1 MarR family HTH_32 PF13565.6 KFM57771.1 - 0.0052 17.4 4.0 0.039 14.6 0.8 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM57771.1 - 0.026 14.5 0.1 0.084 12.9 0.1 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM57771.1 - 0.085 12.4 0.1 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Homeodomain PF00046.29 KFM57773.1 - 2.4e-23 81.7 4.9 3.1e-23 81.4 4.9 1.2 1 0 0 1 1 1 1 Homeodomain LTXXQ PF07813.12 KFM57773.1 - 0.026 15.2 0.1 0.032 15.0 0.1 1.3 1 0 0 1 1 1 0 LTXXQ motif family protein Homeobox_KN PF05920.11 KFM57773.1 - 0.043 13.7 0.2 0.075 12.9 0.2 1.4 1 0 0 1 1 1 0 Homeobox KN domain Sigma70_r3 PF04539.16 KFM57773.1 - 0.074 13.1 0.6 0.33 11.1 0.1 2.1 1 1 1 2 2 2 0 Sigma-70 region 3 DDE_3 PF13358.6 KFM57774.1 - 6.5e-13 48.7 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Homeodomain PF00046.29 KFM57775.1 - 2.1e-21 75.5 4.6 4.4e-21 74.5 4.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM57775.1 - 0.036 14.0 2.2 0.85 9.6 0.5 2.9 2 0 0 2 2 2 0 Homeobox KN domain HTH_Tnp_Tc3_2 PF01498.18 KFM57776.1 - 3.4e-16 59.2 3.7 4.5e-16 58.9 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57776.1 - 9.7e-14 51.3 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HSP70 PF00012.20 KFM57777.1 - 6.4e-257 853.6 1.1 7.2e-257 853.4 1.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM57777.1 - 2.8e-16 59.3 0.0 7.3e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFM57777.1 - 0.0056 17.1 0.5 12 6.4 0.0 3.4 3 1 0 3 3 3 2 Cell division protein FtsA Radial_spoke_3 PF06098.11 KFM57777.1 - 0.023 14.0 5.2 0.038 13.3 5.2 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 Hydantoinase_A PF01968.18 KFM57777.1 - 0.028 13.7 0.4 0.1 11.9 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 KFM57777.1 - 0.043 13.0 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 StbA protein FGGY_C PF02782.16 KFM57777.1 - 0.063 13.0 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain WGG PF10273.9 KFM57778.1 - 2e-18 66.8 0.8 6.5e-18 65.2 0.0 2.0 2 1 0 2 2 2 1 Pre-rRNA-processing protein TSR2 Phage_tube PF04985.14 KFM57778.1 - 0.027 14.2 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Phage tail tube protein FII tRNA_U5-meth_tr PF05958.11 KFM57780.1 - 8e-22 77.7 0.5 3.4e-20 72.4 0.2 2.8 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 KFM57780.1 - 3.9e-13 49.5 0.1 8.4e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM57780.1 - 2e-11 44.4 0.4 6.3e-11 42.8 0.2 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM57780.1 - 4.5e-08 33.6 0.1 1.3e-07 32.2 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFM57780.1 - 1.2e-07 31.4 0.2 4.9e-07 29.4 0.2 2.0 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 KFM57780.1 - 7.1e-07 29.2 0.0 1.8e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KFM57780.1 - 8.6e-07 28.7 0.1 1.8e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 KFM57780.1 - 1.1e-06 28.2 0.1 2.1e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFM57780.1 - 1.8e-06 27.6 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KFM57780.1 - 2.8e-06 27.3 0.0 5.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFM57780.1 - 7.1e-06 26.1 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFM57780.1 - 1.1e-05 25.0 0.8 2.1e-05 24.1 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KFM57780.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KFM57780.1 - 0.00035 20.4 0.1 0.00064 19.5 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein TPMT PF05724.11 KFM57780.1 - 0.00052 19.7 0.3 0.032 13.9 0.2 2.5 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 KFM57780.1 - 0.00093 19.1 0.1 0.0025 17.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFM57780.1 - 0.0018 17.7 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 KFM57780.1 - 0.0027 18.4 0.0 0.007 17.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 KFM57780.1 - 0.041 13.6 3.2 0.075 12.7 0.0 2.6 3 1 0 3 3 3 0 DNA methylase UPF0020 PF01170.18 KFM57780.1 - 2 8.1 3.7 16 5.1 2.8 2.5 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 DUF2678 PF10856.8 KFM57781.1 - 0.17 11.9 2.7 0.27 11.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) HTH_Tnp_Tc3_2 PF01498.18 KFM57782.1 - 2.5e-19 69.3 2.1 4e-19 68.6 2.1 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57782.1 - 3.1e-16 59.4 0.0 1.4e-15 57.3 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM57782.1 - 0.024 15.3 1.4 0.046 14.3 0.4 2.1 2 0 0 2 2 2 0 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.11 KFM57782.1 - 0.11 11.4 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain p53-inducible11 PF14936.6 KFM57783.1 - 8.3e-41 140.0 0.0 1.1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF4345 PF14248.6 KFM57783.1 - 0.0036 17.2 3.1 0.0052 16.7 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) DUF4267 PF14087.6 KFM57783.1 - 0.0062 16.6 0.3 0.0094 16.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Steroid_dh PF02544.16 KFM57785.1 - 9.8e-26 90.5 1.3 1.6e-25 89.9 1.3 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 KFM57785.1 - 0.00012 21.7 0.1 0.0002 21.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Transposase_1 PF01359.18 KFM57786.1 - 2.6e-14 52.8 0.0 4.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM57786.1 - 8.9e-09 35.3 0.1 1.7e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase GRAB PF10375.9 KFM57786.1 - 0.22 11.5 0.5 27 4.8 0.0 2.6 2 0 0 2 2 2 0 GRIP-related Arf-binding domain Cullin PF00888.22 KFM57787.1 - 6e-180 599.9 8.3 1e-179 599.2 8.3 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFM57787.1 - 4.5e-29 100.3 3.9 5.5e-28 96.8 2.9 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain Phage_TAC_12 PF12363.8 KFM57787.1 - 0.017 15.5 0.1 0.14 12.6 0.0 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC KH_1 PF00013.29 KFM57788.1 - 0.001 18.8 0.1 0.0048 16.7 0.0 2.1 2 1 0 2 2 2 1 KH domain DHH PF01368.20 KFM57788.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 DHH family DDE_3 PF13358.6 KFM57790.1 - 4e-05 23.4 0.1 0.00013 21.7 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease Ish1 PF10281.9 KFM57790.1 - 0.076 13.3 0.1 0.83 10.0 0.0 2.6 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KFM57790.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 HeH/LEM domain gag-asp_proteas PF13975.6 KFM57791.1 - 5.9e-09 36.4 0.0 1.4e-08 35.2 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM57791.1 - 4e-08 33.8 0.0 7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KFM57791.1 - 0.011 15.5 0.1 0.026 14.3 0.0 1.6 1 1 1 2 2 2 0 Aspartyl protease RVP PF00077.20 KFM57791.1 - 0.027 14.8 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RasGEF PF00617.19 KFM57794.1 - 1.1e-39 136.4 1.8 1.6e-39 135.9 0.6 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFM57794.1 - 1.2e-30 105.8 0.0 3.5e-30 104.3 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGEF PF00621.20 KFM57794.1 - 4.5e-20 72.6 0.6 4.5e-20 72.6 0.6 2.4 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFM57794.1 - 4.3e-08 33.6 0.1 5.3e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 KFM57794.1 - 0.0012 18.9 0.0 0.0042 17.1 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF2719 PF10891.8 KFM57795.1 - 0.072 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) aGPT-Pplase3 PF18746.1 KFM57795.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 EphA2_TM PF14575.6 KFM57796.1 - 0.0038 18.1 0.0 0.0063 17.4 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KFM57796.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DAG1 PF05454.11 KFM57796.1 - 0.044 13.2 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Ly49 PF08391.10 KFM57796.1 - 0.079 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Protocadherin PF08374.11 KFM57796.1 - 0.081 12.9 0.3 0.2 11.6 0.3 1.5 1 1 0 1 1 1 0 Protocadherin PRIMA1 PF16101.5 KFM57796.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.4 2 1 1 3 3 3 0 Proline-rich membrane anchor 1 LST1 PF05083.13 KFM57796.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 LST-1 protein Myc_target_1 PF15179.6 KFM57796.1 - 0.28 11.0 1.2 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Myc target protein 1 Ig_3 PF13927.6 KFM57797.1 - 4.7e-74 245.0 18.2 4.6e-12 46.4 0.0 7.2 7 0 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 KFM57797.1 - 9e-63 208.4 9.4 1.1e-11 44.6 0.0 7.1 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM57797.1 - 4e-54 180.9 9.0 3.8e-09 36.8 0.1 7.2 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 KFM57797.1 - 2.8e-49 165.2 13.9 2.1e-07 31.0 0.0 7.3 7 0 0 7 7 7 7 Immunoglobulin domain C2-set_2 PF08205.12 KFM57797.1 - 3.2e-35 120.0 5.6 2.3e-07 30.8 0.0 5.6 5 0 0 5 5 5 4 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM57797.1 - 2e-14 53.7 20.1 0.0073 16.5 0.0 10.4 7 5 3 10 10 10 4 Immunoglobulin V-set domain C1-set PF07654.15 KFM57797.1 - 8e-12 45.4 3.2 0.056 13.8 0.0 6.1 6 0 0 6 6 6 3 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM57797.1 - 5e-11 42.7 2.4 0.29 11.4 0.5 7.0 7 1 0 7 7 7 3 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM57797.1 - 8.1e-06 25.8 1.1 37 4.5 0.0 6.0 6 0 0 6 6 6 0 Izumo-like Immunoglobulin domain fn3 PF00041.21 KFM57797.1 - 0.0027 18.0 2.6 0.0055 17.0 0.0 3.0 3 0 0 3 3 3 1 Fibronectin type III domain Putative_PNPOx PF01243.20 KFM57797.1 - 0.022 15.0 0.0 0.24 11.6 0.0 2.6 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DUF5548 PF17702.1 KFM57798.1 - 0.082 12.6 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5548) DDE_3 PF13358.6 KFM57799.1 - 3.6e-11 43.0 0.0 7.9e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease Ig_3 PF13927.6 KFM57800.1 - 1.3e-34 118.7 1.7 1.1e-10 41.9 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM57800.1 - 9.5e-31 105.7 0.0 2.1e-10 40.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFM57800.1 - 2.6e-25 88.4 0.3 1.4e-08 34.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM57800.1 - 5.9e-25 87.4 0.2 1.4e-06 28.6 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain fn3 PF00041.21 KFM57800.1 - 8.7e-13 48.4 0.5 8.3e-08 32.5 0.0 3.4 3 0 0 3 3 3 2 Fibronectin type III domain V-set PF07686.17 KFM57800.1 - 9.9e-11 41.8 1.2 0.013 15.7 0.0 4.7 3 2 1 4 4 4 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM57800.1 - 7.1e-05 22.3 0.0 0.0044 16.5 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM57800.1 - 0.013 15.6 0.0 12 6.0 0.0 3.2 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFM57800.1 - 0.034 14.5 0.0 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFM57800.1 - 0.18 12.3 0.2 30 5.1 0.0 3.3 3 2 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM57801.1 - 5.5e-15 55.2 0.4 8.4e-12 45.0 0.1 2.3 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM57801.1 - 1.5e-12 47.9 1.1 1.4e-10 41.6 0.3 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM57801.1 - 1.3e-09 38.3 0.2 9.9e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM57801.1 - 4e-08 33.3 0.3 2.8e-07 30.6 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM57801.1 - 4.2e-06 26.8 0.1 0.0007 19.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain C1-set PF07654.15 KFM57801.1 - 0.0067 16.8 0.0 0.044 14.2 0.0 2.1 2 1 0 2 2 2 1 Immunoglobulin C1-set domain BiPBP_C PF06832.12 KFM57801.1 - 0.018 15.1 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Ig_4 PF16680.5 KFM57801.1 - 0.065 13.5 0.1 3.7 7.9 0.1 2.9 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM57801.1 - 0.066 13.6 1.0 1.1 9.7 0.3 2.6 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_3 PF13927.6 KFM57802.1 - 1.1e-19 70.7 0.9 8.2e-11 42.4 0.0 2.6 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM57802.1 - 1e-15 57.6 0.0 6.9e-07 29.3 0.0 2.7 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFM57802.1 - 1e-15 57.7 0.0 2.8e-06 27.4 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFM57802.1 - 4.3e-15 55.8 0.1 9.3e-09 35.5 0.0 2.9 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM57802.1 - 1.5e-11 44.2 0.0 1.5e-06 28.1 0.0 2.5 3 0 0 3 3 3 2 Immunoglobulin I-set domain C1-set PF07654.15 KFM57802.1 - 1e-05 25.8 0.0 0.064 13.6 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin C1-set domain BiPBP_C PF06832.12 KFM57802.1 - 2.8e-05 24.1 0.0 0.26 11.3 0.0 2.3 1 1 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family V-set PF07686.17 KFM57802.1 - 0.0029 17.8 0.1 6.4 7.0 0.0 3.4 2 2 1 3 3 3 1 Immunoglobulin V-set domain SH3_2 PF07653.17 KFM57802.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain I-set PF07679.16 KFM57803.1 - 0.0081 16.2 0.0 0.0082 16.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFM57803.1 - 0.022 14.9 0.0 0.022 14.9 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin V-set domain NUFIP1 PF10453.9 KFM57804.1 - 2.4e-14 52.9 8.0 2.4e-14 52.9 8.0 2.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Clathrin_lg_ch PF01086.17 KFM57804.1 - 0.0024 17.9 6.9 0.005 16.9 6.9 1.5 1 0 0 1 1 1 1 Clathrin light chain zf-C2H2_jaz PF12171.8 KFM57804.1 - 0.01 16.1 0.1 0.032 14.5 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFM57804.1 - 0.082 13.4 1.5 0.23 12.0 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM57804.1 - 5.3 7.7 6.4 2.2 8.9 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Pkinase PF00069.25 KFM57805.1 - 1.7e-68 230.8 0.0 2.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57805.1 - 5e-51 173.5 0.0 6.1e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM57805.1 - 5.8e-06 25.3 0.0 9.3e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM57805.1 - 0.0043 16.0 0.2 0.026 13.5 0.2 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM57805.1 - 0.0045 16.3 0.0 0.048 13.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like HTH_27 PF13463.6 KFM57805.1 - 0.43 11.1 1.2 2.1 8.9 0.1 2.4 3 0 0 3 3 3 0 Winged helix DNA-binding domain TMEM171 PF15471.6 KFM57806.1 - 1.2 8.1 4.9 1.7 7.6 4.9 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 HTH_Tnp_Tc3_2 PF01498.18 KFM57807.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57807.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57807.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57807.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57807.1 - 2.1 9.0 15.6 0.12 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF2678 PF10856.8 KFM57808.1 - 2.7e-38 130.5 3.0 3.1e-38 130.3 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) BAR_3_WASP_bdg PF10456.9 KFM57811.1 - 1.9e-63 214.1 2.6 2.1e-63 213.9 2.6 1.0 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Vps5 PF09325.10 KFM57811.1 - 2.9e-08 33.5 0.1 0.00028 20.5 0.8 2.3 1 1 1 2 2 2 2 Vps5 C terminal like SF3b10 PF07189.11 KFM57811.1 - 0.051 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Splicing factor 3B subunit 10 (SF3b10) EST1 PF10374.9 KFM57811.1 - 0.12 13.0 2.1 5.6 7.6 3.0 2.1 1 1 1 2 2 2 0 Telomerase activating protein Est1 PX PF00787.24 KFM57812.1 - 9.8e-23 80.3 1.1 1.3e-22 79.9 0.2 1.6 2 0 0 2 2 2 1 PX domain SH3_1 PF00018.28 KFM57812.1 - 8.7e-14 50.9 0.3 2.9e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFM57812.1 - 1.5e-13 50.4 0.1 3.6e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain BAR_3_WASP_bdg PF10456.9 KFM57812.1 - 1.3e-09 37.9 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein SH3_2 PF07653.17 KFM57812.1 - 3.6e-09 36.2 0.0 5.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ASF1_hist_chap PF04729.13 KFM57813.1 - 2e-73 245.5 0.2 2.4e-73 245.2 0.2 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RTC PF01137.21 KFM57814.1 - 3.1e-55 186.8 0.0 3.5e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KFM57814.1 - 1.7e-37 128.0 0.0 2.5e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DDE_3 PF13358.6 KFM57815.1 - 3.3e-16 59.4 0.1 3.4e-15 56.1 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57815.1 - 1.5e-10 41.2 1.0 2.9e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM57816.1 - 2.3e-16 59.8 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57816.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MLVIN_C PF18697.1 KFM57817.1 - 0.00046 20.2 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_3 PF13358.6 KFM57818.1 - 3.6e-10 39.8 0.0 4.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease GCD14_N PF14801.6 KFM57820.1 - 0.17 11.7 0.1 0.45 10.4 0.1 1.7 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term HTH_Tnp_Tc3_2 PF01498.18 KFM57821.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57821.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5641 PF18701.1 KFM57822.1 - 4.7e-16 58.7 0.0 9.2e-16 57.8 0.0 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5641) Nrap PF03813.14 KFM57822.1 - 0.019 15.0 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Nrap protein domain 1 HTH_Tnp_Tc3_2 PF01498.18 KFM57823.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57823.1 - 9.5e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57824.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57824.1 - 3.7e-14 52.7 0.0 6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57825.1 - 2.5e-16 59.7 2.2 4.5e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57825.1 - 9.5e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MMS1_N PF10433.9 KFM57826.1 - 8e-84 282.0 0.1 6e-83 279.1 0.1 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFM57826.1 - 1.8e-83 280.6 0.2 1.5e-81 274.2 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region Lgl_C PF08596.10 KFM57826.1 - 0.0018 17.1 0.0 0.0039 16.0 0.0 1.5 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal MOZ_SAS PF01853.18 KFM57827.1 - 6.9e-87 289.7 1.0 8.3e-87 289.5 1.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.7 KFM57827.1 - 0.00014 22.2 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM57827.1 - 0.0039 17.4 0.0 0.0067 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-MYST PF17772.1 KFM57828.1 - 2.4e-08 33.5 0.3 3.1e-08 33.1 0.3 1.2 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KFM57829.1 - 3.8e-10 39.5 0.0 7.6e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain MFS_1 PF07690.16 KFM57830.1 - 2.5e-05 23.4 17.8 0.00028 19.9 15.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3311 PF11755.8 KFM57830.1 - 0.098 12.6 0.6 0.098 12.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) TSP_1 PF00090.19 KFM57831.1 - 0.0012 19.0 2.2 0.0012 19.0 2.2 3.5 3 2 0 3 3 3 1 Thrombospondin type 1 domain TRM PF02005.16 KFM57832.1 - 1.8e-134 448.7 0.6 2.3e-134 448.3 0.6 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KFM57832.1 - 2.7e-08 33.8 0.1 4.7e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KFM57832.1 - 0.00012 21.7 0.0 0.00034 20.3 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 KFM57832.1 - 0.032 13.6 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 KFM57832.1 - 0.091 11.9 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.14 KFM57832.1 - 0.11 12.0 0.1 0.27 10.8 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase small domain DUF787 PF05619.11 KFM57834.1 - 0.086 12.0 0.3 0.084 12.0 0.3 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) DDE_3 PF13358.6 KFM57836.1 - 3.7e-16 59.2 0.1 3.7e-15 56.0 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57836.1 - 1.5e-10 41.1 1.0 3e-10 40.2 1.0 1.5 1 0 0 1 1 1 1 Transposase Neur_chan_memb PF02932.16 KFM57837.1 - 1.5e-26 93.9 1.7 2e-26 93.5 1.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region COX1 PF00115.20 KFM57837.1 - 0.0071 15.3 0.6 0.0087 15.0 0.6 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF2678 PF10856.8 KFM57837.1 - 0.073 13.0 0.6 0.12 12.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) EOS1 PF12326.8 KFM57837.1 - 0.17 11.8 3.3 0.21 11.5 3.3 1.1 1 0 0 1 1 1 0 N-glycosylation protein Med27 PF11571.8 KFM57837.1 - 0.55 10.6 9.0 2.6 8.5 0.7 3.2 1 1 0 3 3 3 0 Mediator complex subunit 27 HTH_Tnp_Tc3_2 PF01498.18 KFM57839.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57839.1 - 9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57840.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57840.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PNP_UDP_1 PF01048.20 KFM57843.1 - 7.8e-30 103.9 0.0 8.8e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Dynein_light PF01221.18 KFM57843.1 - 0.097 13.0 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Dynein light chain type 1 REPA_OB_2 PF16900.5 KFM57844.1 - 1.5e-25 88.9 0.3 3.5e-25 87.8 0.3 1.7 1 0 0 1 1 1 1 Replication protein A OB domain Rep_fac-A_C PF08646.10 KFM57844.1 - 1.1e-17 64.1 2.3 2.2e-16 59.9 1.4 2.5 2 0 0 2 2 2 1 Replication factor-A C terminal domain Rep-A_N PF04057.12 KFM57844.1 - 1.4e-11 44.3 0.0 3.6e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KFM57844.1 - 1.4e-11 44.2 0.5 3.9e-09 36.4 0.1 2.7 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain zf-AN1 PF01428.16 KFM57844.1 - 0.15 12.2 2.7 0.4 10.9 2.7 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger Radical_SAM PF04055.21 KFM57845.1 - 1.8e-33 116.2 0.1 3.6e-33 115.3 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 KFM57845.1 - 6e-30 103.2 0.5 1.1e-29 102.3 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Dynamin_M PF01031.20 KFM57845.1 - 0.045 13.0 0.5 1.1 8.4 0.0 2.5 2 1 1 3 3 3 0 Dynamin central region SOBP PF15279.6 KFM57846.1 - 1.1e-58 200.4 80.3 4.7e-49 168.7 42.4 4.1 3 1 1 4 4 4 3 Sine oculis-binding protein Sua5_yciO_yrdC PF01300.18 KFM57847.1 - 2.9e-42 144.2 0.0 3.5e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination Chloroplast_duf PF14476.6 KFM57847.1 - 0.22 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Petal formation-expressed DCB PF16213.5 KFM57848.1 - 3.2e-14 53.0 3.6 4.3e-14 52.6 3.6 1.0 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KFM57848.1 - 0.0083 16.0 1.7 0.088 12.7 0.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1981) Sec7 PF01369.20 KFM57850.1 - 2.7e-06 27.2 0.6 6.9e-06 25.9 0.2 1.9 2 0 0 2 2 2 1 Sec7 domain DUF445 PF04286.12 KFM57850.1 - 0.45 10.3 3.3 0.67 9.7 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF4924 PF16271.5 KFM57851.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) PRESAN PF09687.10 KFM57851.1 - 0.12 12.9 2.6 0.14 12.7 1.0 2.1 2 0 0 2 2 2 0 Plasmodium RESA N-terminal SH3BGR PF04908.15 KFM57851.1 - 0.51 10.5 2.1 20 5.4 0.1 2.6 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Cupin_2 PF07883.11 KFM57853.1 - 0.047 13.4 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Cupin domain cNMP_binding PF00027.29 KFM57853.1 - 0.093 12.8 0.0 0.099 12.7 0.0 1.1 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Runt PF00853.19 KFM57854.1 - 2.4e-43 146.8 0.0 2.7e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Runt domain HTH_Tnp_Tc3_2 PF01498.18 KFM57856.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57856.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57857.1 - 2.6e-16 59.7 0.1 2.9e-15 56.3 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57857.1 - 1.4e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM57858.1 - 7e-15 55.0 0.8 1.3e-14 54.1 0.8 1.5 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM57858.1 - 9.8e-06 25.6 2.1 0.0011 19.0 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.18 KFM57858.1 - 0.00048 20.1 0.2 0.001 19.0 0.2 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFM57858.1 - 0.0006 19.5 4.4 0.015 15.1 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57858.1 - 0.001 19.6 5.2 0.001 19.6 5.2 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_37 PF13744.6 KFM57858.1 - 0.0013 18.6 0.0 0.7 9.9 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 KFM57858.1 - 0.014 15.5 0.7 0.47 10.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.6 KFM57858.1 - 0.023 14.5 7.0 0.025 14.3 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 KFM57858.1 - 0.04 14.0 3.4 1.1 9.4 1.5 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_IS630 PF01710.16 KFM57858.1 - 0.046 13.8 0.1 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Transposase MarR_2 PF12802.7 KFM57858.1 - 0.076 12.9 1.8 0.42 10.5 0.1 2.3 2 0 0 2 2 2 0 MarR family HTH_26 PF13443.6 KFM57858.1 - 0.1 13.1 0.3 3.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 KFM57858.1 - 0.16 11.5 0.6 19 4.9 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Ank_4 PF13637.6 KFM57859.1 - 1.3e-19 70.2 4.3 5.8e-08 33.1 0.4 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM57859.1 - 1.6e-17 63.9 4.4 1.9e-14 54.0 1.5 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFM57859.1 - 1.1e-16 60.4 6.3 0.00019 21.7 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFM57859.1 - 3.1e-12 46.5 2.4 5.1e-07 29.9 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM57859.1 - 6e-12 44.6 3.1 0.002 18.4 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat SOCS_box PF07525.16 KFM57859.1 - 0.00012 22.3 2.6 0.00023 21.4 2.6 1.4 1 0 0 1 1 1 1 SOCS box Peptidase_C8 PF03569.13 KFM57859.1 - 0.036 13.6 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C8 HTH_Tnp_Tc3_2 PF01498.18 KFM57860.1 - 2.3e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57860.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MMS1_N PF10433.9 KFM57861.1 - 1.3e-25 90.0 0.0 2.8e-24 85.6 0.0 2.3 1 1 1 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF2897 PF11446.8 KFM57861.1 - 0.76 9.7 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) MMS1_N PF10433.9 KFM57863.1 - 8.6e-05 21.4 0.0 0.00011 21.0 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Peptidase_S55 PF05580.12 KFM57863.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 SpoIVB peptidase S55 Acetyltransf_1 PF00583.25 KFM57864.1 - 4.7e-16 59.1 0.1 6.5e-16 58.6 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM57864.1 - 1.2e-10 41.6 0.1 1.7e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM57864.1 - 2.8e-09 37.0 0.0 3.7e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFM57864.1 - 1.2e-06 28.8 0.3 1.9e-06 28.1 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM57864.1 - 1.6e-06 28.0 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFM57864.1 - 1.2e-05 25.4 0.0 3.8e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFM57864.1 - 0.00095 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFM57864.1 - 0.0038 17.9 0.0 0.0047 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 KFM57864.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Nudix hydrolase domain 7tm_1 PF00001.21 KFM57865.1 - 1.4e-09 37.7 2.6 1.6e-09 37.5 2.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM57865.1 - 0.032 13.6 9.4 0.045 13.1 6.1 1.8 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx BPD_transp_2 PF02653.16 KFM57865.1 - 0.069 12.3 1.9 0.058 12.6 0.9 1.5 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component Abhydrolase_9_N PF15420.6 KFM57865.1 - 0.38 10.7 8.3 0.023 14.7 2.5 1.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus SAM_1 PF00536.30 KFM57866.1 - 1.2e-06 28.8 0.1 1.6e-06 28.5 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM57866.1 - 3.4e-06 27.1 0.1 4.3e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFM57866.1 - 0.0037 17.2 0.3 0.0054 16.7 0.3 1.3 1 1 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 KFM57866.1 - 0.053 13.3 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF747 PF05346.11 KFM57867.1 - 1.4e-104 350.0 17.3 1.9e-104 349.6 17.3 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family FA_desaturase PF00487.24 KFM57867.1 - 2.9 7.7 0.0 2.9 7.7 0.0 2.9 2 1 1 3 3 3 0 Fatty acid desaturase CPSase_L_D2 PF02786.17 KFM57868.1 - 1.6e-80 269.6 0.1 2.7e-80 268.8 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KFM57868.1 - 2.4e-50 169.6 0.0 4.9e-50 168.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KFM57868.1 - 2.2e-42 145.0 0.0 3.8e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KFM57868.1 - 2.1e-14 53.9 0.1 6e-14 52.4 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 KFM57868.1 - 3.5e-08 33.2 0.1 9.1e-08 31.9 0.1 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.13 KFM57868.1 - 9.6e-06 25.5 0.1 0.0024 17.7 0.0 2.4 1 1 1 2 2 2 2 Peptidase C26 ATPgrasp_Ter PF15632.6 KFM57868.1 - 9e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KFM57868.1 - 0.0081 16.2 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain DJ-1_PfpI PF01965.24 KFM57868.1 - 0.012 15.4 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 DJ-1/PfpI family ATP-grasp_5 PF13549.6 KFM57868.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain Ish1 PF10281.9 KFM57868.1 - 0.31 11.4 1.1 2.1 8.7 0.1 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein OTCace_N PF02729.21 KFM57869.1 - 6.5e-47 159.3 0.0 1.2e-46 158.4 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KFM57869.1 - 3e-31 108.6 0.1 5.7e-31 107.7 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CPSase_L_D2 PF02786.17 KFM57869.1 - 3e-24 85.7 0.0 5.5e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KFM57869.1 - 2.5e-16 60.1 0.0 2.8e-15 56.7 0.0 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 KFM57869.1 - 3e-14 53.0 0.0 9e-14 51.4 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain Amidohydro_1 PF01979.20 KFM57869.1 - 2.5e-10 40.2 0.0 5.9e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Dala_Dala_lig_C PF07478.13 KFM57869.1 - 3.3e-10 39.8 0.0 6.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFM57869.1 - 3.2e-08 33.3 0.0 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFM57869.1 - 0.00051 20.1 0.0 0.0009 19.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KFM57869.1 - 0.00061 19.5 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 KFM57869.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PHR PF08005.12 KFM57871.1 - 1.4e-36 126.4 1.6 2.3e-36 125.7 1.6 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 KFM57871.1 - 2e-25 89.1 0.1 3.5e-24 85.2 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM57871.1 - 1.9e-07 31.1 1.3 4.1e-07 30.0 0.4 2.1 2 1 0 2 2 2 1 BTB And C-terminal Kelch DUF4082 PF13313.6 KFM57871.1 - 0.0033 17.5 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4082) Transposase_1 PF01359.18 KFM57872.1 - 2.2e-23 81.8 0.0 3.5e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM57872.1 - 0.0024 17.6 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57872.1 - 0.0052 17.0 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_11 PF08279.12 KFM57872.1 - 0.007 16.3 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 HTH domain FbpA PF05833.11 KFM57872.1 - 0.02 13.7 0.1 0.035 12.9 0.1 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HTH_24 PF13412.6 KFM57872.1 - 0.1 12.2 0.0 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Enolase_C PF00113.22 KFM57873.1 - 9.5e-153 507.6 0.1 1.3e-152 507.2 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFM57873.1 - 2.9e-59 199.0 0.1 6.4e-59 197.8 0.1 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KFM57873.1 - 2.6e-07 30.4 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFM57873.1 - 0.0093 15.1 1.1 0.016 14.4 0.2 1.8 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus LRR_4 PF12799.7 KFM57874.1 - 3.9e-40 135.2 42.5 1.2e-09 38.2 0.9 6.4 3 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM57874.1 - 1e-25 90.2 26.4 5.9e-10 38.9 0.5 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 KFM57874.1 - 1.6e-21 75.9 43.3 6.4e-07 29.0 5.2 6.5 1 1 5 7 7 7 6 Leucine rich repeat LRR_6 PF13516.6 KFM57874.1 - 3.6e-07 29.7 22.4 0.26 11.4 0.1 8.7 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 KFM57874.1 - 0.0002 21.4 30.3 0.61 10.8 0.2 10.1 8 4 0 8 8 8 1 Leucine Rich Repeat Phage_rep_org_N PF09681.10 KFM57874.1 - 0.084 12.8 12.5 4.7 7.2 0.9 4.3 1 1 2 4 4 4 0 N-terminal phage replisome organiser (Phage_rep_org_N) DUF2322 PF10084.9 KFM57874.1 - 0.22 11.6 8.8 3.5 7.7 0.1 4.3 3 2 3 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2322) DDE_3 PF13358.6 KFM57875.1 - 3.3e-05 23.7 0.1 4.3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57876.1 - 2.5e-08 33.8 0.0 4.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57876.1 - 3.6e-07 30.3 0.1 8.4e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Transposase ACP_PD PF04336.12 KFM57876.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase HTH_32 PF13565.6 KFM57876.1 - 0.15 12.7 6.3 0.099 13.3 3.7 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Peptidase_M13 PF01431.21 KFM57878.1 - 3.2e-08 33.4 0.2 3.3e-08 33.4 0.2 1.0 1 0 0 1 1 1 1 Peptidase family M13 Sulfatase_C PF14707.6 KFM57879.1 - 0.00026 21.7 0.1 0.00046 20.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KFM57879.1 - 0.00067 19.5 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function ANF_receptor PF01094.28 KFM57880.1 - 1.8e-07 30.6 0.0 1.8e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Trypsin_2 PF13365.6 KFM57881.1 - 3.5e-30 105.9 0.4 5.5e-30 105.3 0.4 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFM57881.1 - 8.8e-15 55.1 0.0 1.4e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KFM57881.1 - 1.4e-09 37.7 0.0 3.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM57881.1 - 1.1e-08 35.3 0.0 2.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM57881.1 - 8e-06 26.1 0.0 2.4e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 KFM57881.1 - 2.8e-05 23.0 1.0 0.032 12.9 0.2 2.2 2 0 0 2 2 2 2 Peptidase S46 Tricorn_PDZ PF14685.6 KFM57881.1 - 0.00069 19.5 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain Paf67 PF10255.9 KFM57882.1 - 0.062 12.3 0.4 0.083 11.9 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 DUF4145 PF13643.6 KFM57882.1 - 0.12 12.6 1.5 1.1 9.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) JmjC PF02373.22 KFM57883.1 - 1.2e-28 99.8 0.9 1.2e-28 99.8 0.9 2.3 2 0 0 2 2 1 1 JmjC domain, hydroxylase TPR_1 PF00515.28 KFM57883.1 - 5.4e-19 67.1 6.4 1e-05 25.1 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFM57883.1 - 6.1e-14 51.3 0.5 0.018 15.4 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM57883.1 - 3.5e-10 39.3 1.3 0.027 14.7 0.3 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM57883.1 - 4.6e-10 38.8 4.3 0.063 13.4 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM57883.1 - 1.6e-06 27.7 0.6 0.32 11.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM57883.1 - 3.3e-06 27.3 0.0 0.96 9.8 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM57883.1 - 1.4e-05 25.6 0.0 1.5 9.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM57883.1 - 0.0002 21.0 3.2 0.57 9.9 0.0 4.4 3 2 2 5 5 5 2 TPR repeat TPR_19 PF14559.6 KFM57883.1 - 0.00052 20.5 0.7 6.2 7.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM57883.1 - 0.0053 17.5 0.0 21 6.3 0.1 4.2 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM57883.1 - 0.014 16.0 4.7 0.6 10.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Phage_hub_GP28 PF11110.8 KFM57883.1 - 0.031 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Baseplate hub distal subunit ANAPC3 PF12895.7 KFM57883.1 - 6.1 7.2 9.7 2.1 8.6 0.1 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-H2C2_2 PF13465.6 KFM57884.1 - 2.2e-25 87.9 24.8 7.7e-10 38.7 0.3 4.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57884.1 - 1e-19 69.8 33.0 2e-06 27.9 1.9 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57884.1 - 2.9e-13 49.4 30.4 0.00046 20.8 1.2 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KFM57884.1 - 6.9e-11 42.2 31.0 6.8e-05 23.1 1.8 5.2 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM57884.1 - 3.9e-09 36.3 26.3 0.00026 20.9 0.5 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM57884.1 - 1.2e-08 35.0 19.1 0.0027 18.0 0.6 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM57884.1 - 1.3e-06 28.1 14.9 0.19 11.5 0.1 4.3 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM57884.1 - 3.4e-06 27.0 10.8 0.44 10.6 0.4 4.1 3 1 1 4 4 4 3 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.6 KFM57884.1 - 0.00029 20.5 21.7 0.018 14.8 0.4 4.8 5 0 0 5 5 5 3 C2H2-type zinc-finger domain BolA PF01722.18 KFM57884.1 - 0.0021 18.3 3.4 1.8 8.9 0.4 3.1 1 1 2 3 3 3 1 BolA-like protein zf-C2H2_8 PF15909.5 KFM57884.1 - 0.033 14.5 16.4 0.034 14.4 2.5 2.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon Asp2 PF16929.5 KFM57884.1 - 0.068 12.1 0.2 0.073 12.0 0.2 1.0 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter zf-C2H2_9 PF16293.5 KFM57884.1 - 0.14 12.0 15.9 0.74 9.7 0.4 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (1 copy) SPARC_Ca_bdg PF10591.9 KFM57884.1 - 0.2 12.0 8.4 3.8 7.9 0.4 3.3 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region zinc_ribbon_15 PF17032.5 KFM57884.1 - 0.28 12.0 17.6 2.4 8.9 2.8 2.5 1 1 1 2 2 2 0 zinc-ribbon family ADK_lid PF05191.14 KFM57884.1 - 0.52 10.3 10.6 0.16 12.0 1.3 3.0 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-RRPl_C4 PF17026.5 KFM57884.1 - 0.82 9.8 19.9 6.6 6.9 8.7 2.4 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM57884.1 - 0.94 9.6 24.0 2.9 8.1 0.1 5.2 4 1 1 5 5 5 0 DBF zinc finger GAGA PF09237.11 KFM57884.1 - 1 9.2 0.1 1 9.2 0.1 3.7 1 1 3 4 4 4 0 GAGA factor IGPD PF00475.18 KFM57884.1 - 2 8.7 6.1 3.3 8.0 0.1 2.8 1 1 1 3 3 3 0 Imidazoleglycerol-phosphate dehydratase Zf_RING PF16744.5 KFM57884.1 - 2.7 8.2 18.6 2.3 8.4 0.2 4.3 1 1 4 5 5 5 0 KIAA1045 RING finger FYVE PF01363.21 KFM57884.1 - 6.8 6.9 23.0 45 4.3 17.1 3.2 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFM57884.1 - 8.1 6.8 32.2 4.5 7.7 1.1 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM57885.1 - 5.8e-10 39.1 2.7 2.2e-06 27.8 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57885.1 - 6.1e-08 32.7 2.5 1e-07 32.0 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57885.1 - 0.00013 22.5 1.8 0.00021 21.8 1.8 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 KFM57885.1 - 0.0013 19.0 1.5 0.002 18.5 1.5 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM57885.1 - 0.0041 17.4 0.3 0.0061 16.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM57885.1 - 0.0061 16.4 1.2 0.0086 16.0 1.0 1.4 1 1 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFM57885.1 - 0.023 14.7 0.5 0.041 13.9 0.5 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-UBP PF02148.19 KFM57885.1 - 0.033 14.5 0.4 0.038 14.3 0.4 1.1 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_A17 PF05380.13 KFM57886.1 - 1.5e-08 34.8 0.0 2.2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Pao retrotransposon peptidase zf-CCHC_5 PF14787.6 KFM57887.1 - 0.042 13.6 3.6 0.45 10.3 3.0 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-H2C2_2 PF13465.6 KFM57888.1 - 1.1e-83 272.2 76.2 4.4e-08 33.2 1.5 13.2 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57888.1 - 2.2e-46 153.8 101.8 4.1e-06 27.0 1.7 13.1 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57888.1 - 5.3e-40 132.6 92.1 0.00026 21.6 0.9 13.2 13 1 0 13 13 13 11 C2H2-type zinc finger zf-met PF12874.7 KFM57888.1 - 2.2e-29 100.9 93.4 0.00024 21.4 1.0 12.3 13 0 0 13 13 12 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM57888.1 - 4.7e-25 87.3 63.6 0.018 15.3 0.5 12.2 11 1 1 12 12 12 11 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM57888.1 - 1.9e-22 78.7 64.3 0.0028 17.6 0.8 12.4 12 0 0 12 12 12 9 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM57888.1 - 4.6e-16 58.2 66.0 0.029 14.1 0.9 12.7 13 1 0 13 13 13 9 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM57888.1 - 1.3e-11 44.0 63.9 0.051 13.3 0.4 11.4 11 0 0 11 11 11 7 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM57888.1 - 9.8e-10 38.3 34.0 0.24 11.5 0.0 11.0 9 2 2 11 11 11 2 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM57888.1 - 2.4e-07 30.8 51.3 0.0014 18.7 6.1 5.5 1 1 4 5 5 5 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2HC_2 PF13913.6 KFM57888.1 - 1.4e-06 28.0 51.6 0.082 12.8 0.6 11.4 13 0 0 13 13 13 4 zinc-finger of a C2HC-type BolA PF01722.18 KFM57888.1 - 0.00013 22.2 16.8 7.1 7.0 0.2 7.7 2 2 4 6 6 6 1 BolA-like protein zf-DBF PF07535.12 KFM57888.1 - 0.00016 21.7 42.4 7.1 6.8 0.2 11.1 11 0 0 11 11 11 1 DBF zinc finger ADK_lid PF05191.14 KFM57888.1 - 0.0002 21.3 40.2 0.3 11.1 1.3 7.7 7 1 2 9 9 9 3 Adenylate kinase, active site lid C1_1 PF00130.22 KFM57888.1 - 0.0004 20.2 64.6 0.038 13.9 5.5 9.8 3 3 5 9 9 9 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_9 PF16293.5 KFM57888.1 - 0.0081 16.0 53.5 0.69 9.8 0.2 10.7 3 2 9 12 12 12 3 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFM57888.1 - 0.0088 16.1 44.2 22 5.2 0.1 11.2 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) Tox-HNH-HHH PF15637.6 KFM57888.1 - 0.013 15.7 6.5 56 4.0 0.0 5.4 1 1 6 7 7 7 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zinc_ribbon_15 PF17032.5 KFM57888.1 - 0.015 16.0 52.2 0.72 10.6 3.4 6.7 1 1 4 7 7 7 0 zinc-ribbon family Mga PF05043.13 KFM57888.1 - 0.085 13.5 5.7 22 5.7 0.0 4.8 5 0 0 5 5 5 0 Mga helix-turn-helix domain zf-FPG_IleRS PF06827.14 KFM57888.1 - 0.36 10.7 31.9 15 5.6 0.1 10.1 10 1 0 10 10 10 0 Zinc finger found in FPG and IleRS FYVE PF01363.21 KFM57888.1 - 1.8 8.7 59.3 3.7 7.8 8.2 6.4 2 1 5 7 7 6 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 KFM57888.1 - 7.8 6.7 42.4 3.6 7.8 2.2 7.0 3 2 5 8 8 8 0 Zinc ribbon domain V-ATPase_C PF03223.15 KFM57889.1 - 9.3e-109 364.2 5.0 1e-108 364.0 5.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C SH3_9 PF14604.6 KFM57890.1 - 2.7e-07 30.3 0.0 6.8e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain O-FucT PF10250.9 KFM57890.1 - 2.9e-05 23.9 0.0 4.9e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NodZ PF05830.11 KFM57890.1 - 0.00051 18.9 0.2 0.0011 17.9 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein Z (NodZ) SH3_1 PF00018.28 KFM57890.1 - 0.00056 19.5 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain IL3 PF02059.15 KFM57890.1 - 0.019 15.0 1.7 0.067 13.2 1.7 2.1 1 1 0 1 1 1 0 Interleukin-3 PRNT PF15174.6 KFM57890.1 - 0.076 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Prion-related protein testis-specific DUF4532 PF15046.6 KFM57890.1 - 0.15 11.3 0.2 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4532) HalX PF08663.10 KFM57890.1 - 0.17 12.2 0.2 0.17 12.2 0.2 2.1 2 0 0 2 2 2 0 HalX domain NYD-SP28_assoc PF14775.6 KFM57890.1 - 6.9 6.9 9.2 1.6 8.9 2.5 2.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF3923 PF13061.6 KFM57892.1 - 0.014 15.4 0.1 0.02 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3923) DDE_3 PF13358.6 KFM57893.1 - 6.9e-16 58.3 0.1 8e-15 54.9 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57893.1 - 9.5e-16 57.8 6.5 1.7e-15 57.0 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57893.1 - 0.00083 19.9 1.5 0.00083 19.9 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57893.1 - 0.0035 17.1 0.1 0.13 12.1 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57893.1 - 0.019 15.1 0.1 0.074 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57893.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix RPAP2_Rtr1 PF04181.13 KFM57894.1 - 7.8e-23 80.6 4.7 2.8e-22 78.8 4.7 2.0 1 0 0 1 1 1 1 Rtr1/RPAP2 family Virul_Fac PF10139.9 KFM57894.1 - 0.53 8.4 5.8 0.074 11.3 1.2 1.6 1 1 1 2 2 2 0 Putative bacterial virulence factor DUF4598 PF15370.6 KFM57894.1 - 9.3 6.8 11.9 19 5.8 4.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) C2 PF00168.30 KFM57898.1 - 4.2e-10 39.8 0.1 4.7e-10 39.7 0.1 1.0 1 0 0 1 1 1 1 C2 domain Thioredoxin PF00085.20 KFM57899.1 - 0.00014 21.8 0.0 0.00018 21.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KFM57899.1 - 0.16 10.9 0.0 0.19 10.7 0.0 1.0 1 0 0 1 1 1 0 Phosducin PBP PF01161.20 KFM57900.1 - 2.9e-21 76.2 0.1 4.6e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ion_trans_2 PF07885.16 KFM57903.1 - 0.00047 20.1 0.7 0.0085 16.0 0.0 2.2 2 0 0 2 2 2 2 Ion channel HTH_Tnp_Tc3_2 PF01498.18 KFM57904.1 - 2.2e-16 59.8 2.7 4.2e-16 58.9 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57904.1 - 8.8e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease AT_hook PF02178.19 KFM57905.1 - 0.016 15.0 5.9 0.041 13.8 5.9 1.7 1 0 0 1 1 1 0 AT hook motif DUF4835 PF16119.5 KFM57907.1 - 0.05 12.7 0.0 0.05 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) HTH_Tnp_Tc3_2 PF01498.18 KFM57909.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57909.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM57910.1 - 5.3e-16 58.7 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57910.1 - 9.3e-16 57.8 6.5 1.6e-15 57.1 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57910.1 - 0.0008 20.0 1.5 0.0008 20.0 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM57910.1 - 0.0017 18.1 0.0 0.065 13.1 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM57910.1 - 0.014 15.5 0.1 0.051 13.7 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM57910.1 - 0.027 14.5 2.1 0.034 14.1 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM57910.1 - 0.028 14.2 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase Peptidase_M24 PF00557.24 KFM57911.1 - 1.6e-49 168.4 0.0 2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 ChaC PF04752.12 KFM57912.1 - 5.8e-55 186.1 0.0 7.1e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein PhnH PF05845.12 KFM57912.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) DDE_3 PF13358.6 KFM57913.1 - 2.9e-12 46.5 0.0 4.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2315 PF10231.9 KFM57914.1 - 3e-38 130.7 8.1 3e-38 130.7 8.1 1.6 2 0 0 2 2 2 1 Apoptogenic protein 1 Fam20C PF06702.12 KFM57914.1 - 0.67 9.7 4.6 1 9.1 4.6 1.3 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 DUF812 PF05667.11 KFM57915.1 - 0.057 12.3 3.9 0.054 12.4 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_2 PF07716.15 KFM57916.1 - 5e-08 32.9 9.5 9.4e-08 32.0 9.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM57916.1 - 6.9e-06 26.1 8.3 1.3e-05 25.2 8.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFM57916.1 - 0.012 16.1 2.5 0.027 15.0 2.5 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Fis1_TPR_C PF14853.6 KFM57917.1 - 5.8e-05 23.1 0.1 7.4e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat EF-hand_1 PF00036.32 KFM57918.1 - 3.6e-17 60.6 1.5 1.5e-06 27.3 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFM57918.1 - 9.8e-16 58.0 0.6 1.7e-07 31.6 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM57918.1 - 2.3e-15 55.2 2.7 6.1e-07 28.9 0.2 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 KFM57918.1 - 4.6e-09 36.5 0.0 5.7e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KFM57918.1 - 3.7e-08 33.1 3.3 0.0013 18.5 0.2 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFM57918.1 - 7e-08 31.6 2.2 0.001 18.5 0.0 2.6 2 0 0 2 2 2 2 EF hand UPF0154 PF03672.13 KFM57918.1 - 0.0054 16.7 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 KFM57918.1 - 0.054 13.8 0.1 0.51 10.7 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain DUF3349 PF11829.8 KFM57918.1 - 0.082 13.7 0.0 7.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) GPHH PF16905.5 KFM57918.1 - 0.15 11.8 0.0 3.1 7.6 0.0 2.4 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated Integrase_H2C2 PF17921.1 KFM57919.1 - 6.9e-17 61.3 0.2 1.4e-16 60.4 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 KFM57919.1 - 1.5e-08 34.8 0.0 5.4e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KFM57919.1 - 3.5e-06 27.2 0.0 8.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KFM57919.1 - 0.00036 20.7 1.7 0.00067 19.8 1.7 1.5 1 0 0 1 1 1 1 H2C2 zinc finger HLH PF00010.26 KFM57920.1 - 1.8e-17 63.0 1.9 5.6e-17 61.4 1.9 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MRP-S31 PF15433.6 KFM57920.1 - 4.5 6.9 9.4 1.6 8.3 4.3 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 TUDOR PF00567.24 KFM57921.1 - 1.5e-29 102.5 0.1 3.9e-29 101.1 0.0 1.7 2 0 0 2 2 2 1 Tudor domain KH_1 PF00013.29 KFM57921.1 - 4e-20 71.4 2.3 1.4e-14 53.7 0.1 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KFM57921.1 - 0.0018 18.0 0.2 0.0063 16.3 0.2 1.9 1 0 0 1 1 1 1 KH domain DUF2067 PF09840.9 KFM57921.1 - 0.051 13.1 2.6 1 8.9 0.7 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2067) Agenet PF05641.12 KFM57921.1 - 0.091 13.2 0.1 0.71 10.4 0.0 2.5 2 0 0 2 2 2 0 Agenet domain DUF3188 PF11384.8 KFM57921.1 - 1 9.1 3.6 4.1 7.2 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Integrase_H2C2 PF17921.1 KFM57922.1 - 4.5e-08 33.1 0.2 6.8e-08 32.5 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM57922.1 - 1.8e-06 28.1 1.5 4.4e-06 26.8 0.2 2.2 2 0 0 2 2 2 1 H2C2 zinc finger Ran-binding PF05508.11 KFM57922.1 - 0.11 11.4 0.0 6.2 5.7 0.0 2.1 2 0 0 2 2 2 0 RanGTP-binding protein Apt1 PF10351.9 KFM57924.1 - 0.0017 17.3 16.4 0.0019 17.2 16.4 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Dsh_C PF12316.8 KFM57924.1 - 0.021 15.2 32.1 0.031 14.7 32.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Nop14 PF04147.12 KFM57924.1 - 0.055 11.7 21.5 0.071 11.3 21.5 1.0 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 KFM57924.1 - 0.18 10.3 18.6 0.24 9.9 18.6 1.2 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 KFM57924.1 - 0.53 10.2 20.1 0.72 9.7 20.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 KFM57924.1 - 1 8.1 16.7 1.4 7.6 16.7 1.2 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 KFM57924.1 - 1.5 8.1 7.3 2.3 7.5 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SOBP PF15279.6 KFM57924.1 - 1.7 9.2 19.6 2.2 8.8 19.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Ctr PF04145.15 KFM57924.1 - 2 9.0 6.1 1.1e+02 3.4 6.0 2.2 1 1 0 1 1 1 0 Ctr copper transporter family CDC45 PF02724.14 KFM57924.1 - 2.2 6.5 18.5 3.1 6.0 18.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KFM57924.1 - 5.5 6.3 29.5 7.1 5.9 29.5 1.0 1 0 0 1 1 1 0 SDA1 GREB1 PF15782.5 KFM57924.1 - 6.3 3.8 15.7 6.7 3.7 15.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 KFM57924.1 - 8.5 6.1 18.3 12 5.6 18.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 KFM57924.1 - 9.2 4.9 15.8 12 4.5 15.8 1.1 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 KFM57924.1 - 9.4 5.1 12.0 12 4.8 12.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DDE_3 PF13358.6 KFM57925.1 - 1.8e-14 53.7 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM57925.1 - 3.5e-14 52.8 1.1 6.8e-14 51.9 1.1 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM57925.1 - 0.00033 21.2 3.3 0.0051 17.4 0.1 2.9 3 0 0 3 3 3 1 Homeodomain-like domain FUR PF01475.19 KFM57925.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family Reprolysin PF01421.19 KFM57926.1 - 1.7e-15 57.5 0.0 4.4e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFM57926.1 - 6.2e-13 49.1 1.3 6.2e-13 49.1 1.3 3.3 3 0 0 3 3 3 1 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 KFM57926.1 - 4.6e-10 40.1 0.2 1.9e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFM57926.1 - 6e-10 39.3 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM57926.1 - 6.8e-09 36.1 0.0 1.5e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Pep_M12B_propep PF01562.19 KFM57926.1 - 8.5e-08 32.5 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 KFM57926.1 - 0.00076 19.2 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFM57926.1 - 0.007 16.2 0.1 0.018 14.9 0.1 1.7 2 1 0 2 2 2 1 Matrixin zf-H2C2_2 PF13465.6 KFM57927.1 - 1.1e-05 25.7 7.1 0.0021 18.4 0.8 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57927.1 - 5.6e-05 23.4 3.3 7.8e-05 22.9 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57927.1 - 6.3e-05 23.5 1.7 9.5e-05 22.9 1.7 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger HNH_5 PF14279.6 KFM57927.1 - 0.00018 21.3 0.2 0.00019 21.2 0.2 1.1 1 0 0 1 1 1 1 HNH endonuclease zf-C2H2_6 PF13912.6 KFM57927.1 - 0.0049 16.8 3.7 0.0049 16.8 3.7 2.2 1 1 1 2 2 2 1 C2H2-type zinc finger CpXC PF14353.6 KFM57927.1 - 0.012 15.7 0.1 0.012 15.7 0.1 1.0 1 0 0 1 1 1 0 CpXC protein zf-met PF12874.7 KFM57927.1 - 0.023 15.1 2.4 0.044 14.2 2.4 1.7 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFM57927.1 - 0.059 13.0 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFM57927.1 - 0.072 13.4 1.9 0.072 13.4 1.9 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Cas_TM1802 PF09484.10 KFM57927.1 - 0.17 10.6 1.6 0.18 10.5 1.6 1.0 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) zf-H2C2_2 PF13465.6 KFM57928.1 - 1.8e-09 37.6 10.5 6.5e-06 26.3 1.6 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57928.1 - 8.7e-06 25.9 7.1 9.4e-06 25.8 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.7 KFM57928.1 - 3.4e-05 24.1 1.7 3.4e-05 24.1 1.7 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM57928.1 - 0.001 19.7 1.4 0.001 19.7 1.4 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM57928.1 - 0.002 18.4 0.6 0.002 18.4 0.6 2.6 1 1 2 3 3 3 1 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM57928.1 - 0.0061 16.4 0.2 0.058 13.2 0.0 1.9 1 1 1 2 2 2 1 GAGA factor C1_1 PF00130.22 KFM57928.1 - 0.015 15.2 4.6 0.39 10.7 0.3 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_6 PF13912.6 KFM57928.1 - 0.055 13.5 6.8 0.11 12.6 0.8 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger DUF2256 PF10013.9 KFM57928.1 - 0.079 13.1 2.4 1.8 8.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.16 KFM57928.1 - 0.39 10.6 4.7 2.6 8.0 0.4 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-H2C2_2 PF13465.6 KFM57929.1 - 2.9e-68 223.5 77.1 5e-08 33.0 1.1 11.6 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57929.1 - 1.9e-53 176.0 84.0 1.1e-05 25.6 0.6 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57929.1 - 7.5e-39 129.0 77.7 0.0011 19.7 2.0 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM57929.1 - 2.1e-35 120.0 64.7 1.3e-05 25.4 0.3 11.2 11 0 0 11 11 11 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM57929.1 - 1.5e-23 82.5 58.2 0.0027 17.9 0.3 11.3 11 0 0 11 11 11 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM57929.1 - 1.9e-17 62.8 78.2 0.0058 16.6 0.9 12.0 12 1 0 12 12 11 10 C2H2-type zinc finger BolA PF01722.18 KFM57929.1 - 9.6e-07 29.0 9.8 0.56 10.5 0.6 6.0 1 1 4 5 5 5 2 BolA-like protein GAGA PF09237.11 KFM57929.1 - 8e-06 25.6 16.4 0.42 10.5 0.0 6.6 2 2 6 8 8 8 2 GAGA factor ADK_lid PF05191.14 KFM57929.1 - 2.7e-05 24.1 37.8 0.11 12.5 2.7 6.9 3 1 4 7 7 7 4 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KFM57929.1 - 0.00018 21.2 54.4 0.47 10.2 1.4 10.2 10 0 0 10 10 10 3 C2H2-type zinc-finger domain zf_UBZ PF18439.1 KFM57929.1 - 0.0071 15.9 46.9 2 8.1 0.1 10.6 11 0 0 11 11 11 3 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM57929.1 - 0.021 14.7 43.0 2.6 8.0 0.8 10.0 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-AN1 PF01428.16 KFM57929.1 - 0.021 15.0 0.9 0.021 15.0 0.9 10.2 10 1 1 11 11 11 0 AN1-like Zinc finger zf-C2H2_9 PF16293.5 KFM57929.1 - 0.033 14.0 39.2 6.3 6.7 0.1 9.8 4 2 7 11 11 11 0 C2H2 type zinc-finger (1 copy) zf-CHCC PF10276.9 KFM57929.1 - 0.041 13.9 23.9 11 6.1 0.0 9.1 10 0 0 10 10 10 0 Zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM57929.1 - 0.049 13.7 33.1 21 5.2 0.3 9.6 9 1 1 10 10 10 0 Sec23/Sec24 zinc finger Prok-RING_1 PF14446.6 KFM57929.1 - 0.052 13.5 48.3 4.1 7.4 0.2 10.4 11 0 0 11 11 11 0 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.7 KFM57929.1 - 0.064 13.6 64.8 2.2 8.7 0.7 9.2 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KFM57929.1 - 0.1 12.7 52.7 0.11 12.7 4.2 6.5 2 1 1 5 5 5 0 FYVE zinc finger YyzF PF14116.6 KFM57929.1 - 0.47 10.5 44.4 5.3 7.2 0.4 10.4 11 0 0 11 11 11 0 YyzF-like protein zf-RRPl_C4 PF17026.5 KFM57929.1 - 0.51 10.5 46.4 0.082 13.0 3.7 5.2 1 1 4 5 5 4 0 Putative ribonucleoprotein zinc-finger pf C4 type C5HCH PF17982.1 KFM57929.1 - 1.1 9.4 49.2 19 5.5 0.3 10.5 7 3 3 11 11 11 0 NSD Cys-His rich domain zinc-ribbons_6 PF07191.12 KFM57929.1 - 1.6 8.8 46.1 1.3 9.0 1.4 8.1 1 1 4 5 5 4 0 zinc-ribbons zinc_ribbon_15 PF17032.5 KFM57929.1 - 4.6 8.1 46.4 2 9.2 1.7 6.0 1 1 5 7 7 7 0 zinc-ribbon family DUF4990 PF16380.5 KFM57929.1 - 7.4 6.7 8.4 40 4.3 0.0 5.6 7 2 2 9 9 9 0 Domain of unknown function Dynein_light PF01221.18 KFM57931.1 - 6.2e-39 132.2 2.7 1.3e-38 131.2 2.7 1.6 1 0 0 1 1 1 1 Dynein light chain type 1 Orbi_VP1 PF05788.12 KFM57931.1 - 0.03 11.9 0.0 0.037 11.6 0.0 1.0 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) WD40 PF00400.32 KFM57932.1 - 7.6e-11 42.4 1.3 0.011 16.6 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM57932.1 - 0.00013 22.1 0.0 2 8.8 0.0 4.2 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UBA2_C PF16195.5 KFM57932.1 - 0.031 15.0 1.0 0.061 14.0 1.0 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Sld3_N PF18523.1 KFM57932.1 - 0.078 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Sld3 N-terminal domain YL1 PF05764.13 KFM57933.1 - 0.24 11.5 6.8 0.32 11.1 6.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PHD PF00628.29 KFM57933.1 - 0.39 10.6 6.7 0.5 10.3 4.9 2.0 1 1 1 2 2 2 0 PHD-finger MOLO1 PF17175.4 KFM57934.1 - 1.6e-24 86.3 0.2 3.4e-24 85.2 0.2 1.6 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 KFM57934.1 - 1.7e-09 37.9 0.1 1.4e-08 35.0 0.1 2.1 1 1 0 1 1 1 1 TPM domain Glyco_hydro_98C PF08307.11 KFM57934.1 - 0.017 14.6 0.3 0.035 13.6 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 98 C-terminal domain EphA2_TM PF14575.6 KFM57934.1 - 0.05 14.5 0.0 0.25 12.2 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain OppC_N PF12911.7 KFM57934.1 - 0.2 11.6 0.9 2.9 7.9 0.4 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF4806 PF16064.5 KFM57935.1 - 4.1e-08 33.4 0.0 8.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4806) Pox_A11 PF05061.13 KFM57937.1 - 0.019 14.2 1.4 0.035 13.4 0.3 1.9 1 1 1 2 2 2 0 Poxvirus A11 Protein DUF1512 PF07431.12 KFM57937.1 - 0.049 12.6 0.1 0.069 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DUF2280 PF10045.9 KFM57937.1 - 0.07 13.4 0.3 0.19 12.0 0.3 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2280) DUF4317 PF14199.6 KFM57938.1 - 0.012 14.8 0.0 0.79 8.8 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4317) GIY-YIG PF01541.24 KFM57938.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain BRD4_CDT PF17105.5 KFM57938.1 - 2.3 7.9 8.9 56 3.4 0.0 5.0 5 0 0 5 5 5 0 C-terminal domain of bromodomain protein 4 DDE_3 PF13358.6 KFM57939.1 - 5.1e-11 42.5 0.0 6.5e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease CNH PF00780.22 KFM57940.1 - 3.2e-35 122.1 0.0 4.8e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain PBD PF00786.28 KFM57940.1 - 0.0085 16.4 0.1 0.02 15.2 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase PF00069.25 KFM57941.1 - 7.4e-54 182.9 0.0 7.4e-54 182.9 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain KELK PF15796.5 KFM57941.1 - 2.4e-28 98.4 18.6 2.4e-28 98.4 18.6 6.8 4 2 2 6 6 6 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase_Tyr PF07714.17 KFM57941.1 - 1.4e-25 90.1 0.0 3.6e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFM57941.1 - 3e-09 36.6 7.9 3e-09 36.6 7.9 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFM57941.1 - 4.1e-07 29.6 0.0 4.1e-07 29.6 0.0 3.1 3 1 1 4 4 4 1 Kinase-like Myosin_tail_1 PF01576.19 KFM57941.1 - 5.4e-06 24.5 102.0 2.7e-05 22.2 67.1 2.8 1 1 1 2 2 2 2 Myosin tail DMPK_coil PF08826.10 KFM57941.1 - 0.00047 20.2 8.3 0.00047 20.2 8.3 8.1 7 2 2 9 9 9 3 DMPK coiled coil domain like Pkinase_C PF00433.24 KFM57941.1 - 0.00064 20.4 2.5 0.00064 20.4 2.5 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain PI_PP_I PF18363.1 KFM57941.1 - 1.2 9.4 13.3 0.029 14.5 1.1 4.2 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain APH PF01636.23 KFM57941.1 - 9.4 6.1 6.3 0.82 9.5 0.1 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family THAP PF05485.12 KFM57942.1 - 2.6e-11 44.3 3.9 2.6e-11 44.3 3.9 3.6 4 0 0 4 4 4 1 THAP domain CENP-F_leu_zip PF10473.9 KFM57942.1 - 0.027 14.5 0.5 0.027 14.5 0.5 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KFM57942.1 - 0.18 11.6 0.7 0.51 10.2 0.7 1.7 1 0 0 1 1 1 0 Septum formation initiator Dimer_Tnp_hAT PF05699.14 KFM57943.1 - 1.7e-06 27.7 0.0 1.8e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region B-block_TFIIIC PF04182.12 KFM57945.1 - 1.1e-10 41.5 1.0 7e-10 38.9 0.2 2.8 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_Tnp_Tc3_2 PF01498.18 KFM57946.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM57946.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM57946.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM57946.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM57946.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain FAM176 PF14851.6 KFM57947.1 - 6.2e-05 22.7 2.6 7.7e-05 22.4 0.0 2.1 1 1 1 2 2 2 1 FAM176 family HTH_Tnp_Tc3_2 PF01498.18 KFM57949.1 - 2.7e-13 50.0 4.0 5.4e-13 49.0 4.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57949.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_12 PF08461.10 KFM57949.1 - 0.012 15.6 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Sec1 PF00995.23 KFM57951.1 - 4.2e-83 280.5 2.1 5e-83 280.3 2.1 1.0 1 0 0 1 1 1 1 Sec1 family Not1 PF04054.15 KFM57953.1 - 4e-152 506.4 4.2 1e-151 505.1 4.2 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KFM57953.1 - 6.8e-95 316.7 4.0 1.4e-94 315.7 4.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 KFM57953.1 - 2.2e-69 232.4 0.0 2.7e-39 134.3 0.0 2.5 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 KFM57953.1 - 8.4e-52 175.0 3.9 2.7e-51 173.4 3.9 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 KFM57953.1 - 7.6e-51 172.1 0.1 2.1e-50 170.7 0.1 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat zf-H2C2_2 PF13465.6 KFM57955.1 - 1.1e-40 136.2 100.6 9.4e-08 32.2 0.7 11.9 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM57955.1 - 4.9e-30 102.3 107.0 0.00097 19.5 2.1 11.4 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM57955.1 - 6.5e-23 79.4 98.0 0.0038 18.0 0.7 11.5 11 0 0 11 11 11 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM57955.1 - 2.1e-16 59.4 76.6 1.4e-06 27.9 4.6 10.2 10 1 0 10 10 10 6 C2H2-type zinc-finger domain zf-met PF12874.7 KFM57955.1 - 2.7e-05 24.4 42.6 0.023 15.1 0.4 8.1 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM57955.1 - 0.0051 17.1 0.1 0.0051 17.1 0.1 9.5 9 1 1 10 10 10 4 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM57955.1 - 0.007 16.6 1.1 2.2 8.6 0.0 3.4 2 1 0 2 2 2 1 BolA-like protein zf-C2H2_11 PF16622.5 KFM57955.1 - 0.21 11.4 51.9 0.06 13.1 0.8 9.9 10 0 0 10 10 10 0 zinc-finger C2H2-type DUF1917 PF08939.10 KFM57956.1 - 0.00011 22.2 0.2 0.00016 21.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Imm51 PF15595.6 KFM57956.1 - 0.053 13.5 0.1 0.14 12.1 0.1 2.0 1 1 0 1 1 1 0 Immunity protein 51 DUF1917 PF08939.10 KFM57957.1 - 0.00018 21.5 0.2 0.00033 20.6 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) GGGtGRT PF14057.6 KFM57957.1 - 0.13 11.2 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 GGGtGRT protein Pkinase PF00069.25 KFM57958.1 - 3.2e-22 79.1 0.0 3.9e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM57958.1 - 4.8e-12 45.7 0.0 5.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM57958.1 - 0.025 13.5 4.5 0.68 8.8 4.5 2.0 1 1 0 1 1 1 0 Haspin like kinase domain HTH_Tnp_Tc3_2 PF01498.18 KFM57960.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM57960.1 - 9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Brix PF04427.18 KFM57961.1 - 7.6e-19 68.6 0.5 7.6e-19 68.6 0.5 1.7 2 0 0 2 2 2 1 Brix domain Sde2_N_Ubi PF13019.6 KFM57961.1 - 0.19 11.5 5.2 0.4 10.5 5.2 1.5 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain DUF4381 PF14316.6 KFM57962.1 - 0.0019 18.5 0.5 0.004 17.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) DcuC PF03606.15 KFM57962.1 - 0.044 12.2 0.1 0.069 11.6 0.1 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier ASFV_J13L PF05568.11 KFM57962.1 - 0.059 13.1 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein EphA2_TM PF14575.6 KFM57962.1 - 0.094 13.6 0.6 0.56 11.1 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NOP5NT PF08156.13 KFM57962.1 - 0.16 12.4 0.1 0.5 10.8 0.0 1.9 2 0 0 2 2 2 0 NOP5NT (NUC127) domain Neur_chan_memb PF02932.16 KFM57962.1 - 3.2 7.7 5.7 6.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf_Hakai PF18408.1 KFM57963.1 - 3.7e-19 68.1 1.2 7.8e-19 67.1 1.2 1.6 1 0 0 1 1 1 1 C2H2 Hakai zinc finger domain zf-C3HC4_2 PF13923.6 KFM57963.1 - 0.00013 21.7 10.6 0.00042 20.1 10.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM57963.1 - 0.00014 21.6 12.9 0.00025 20.8 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM57963.1 - 0.003 17.5 12.3 0.0057 16.6 12.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM57963.1 - 0.021 14.7 10.9 0.05 13.5 10.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFM57963.1 - 0.033 14.2 4.3 0.11 12.6 4.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM57963.1 - 0.064 13.1 13.8 0.3 11.0 13.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-LITAF-like PF10601.9 KFM57963.1 - 0.17 12.2 6.2 0.36 11.1 6.2 1.5 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain zf-RING_2 PF13639.6 KFM57963.1 - 0.2 12.0 13.5 0.38 11.1 13.5 1.5 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 KFM57963.1 - 0.68 10.0 8.0 1.6 8.8 8.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KFM57963.1 - 0.94 9.5 9.7 1.6 8.8 9.7 1.3 1 0 0 1 1 1 0 zinc-ribbons DUF1272 PF06906.11 KFM57963.1 - 6.5 6.9 10.4 4.7 7.4 8.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) HHH_5 PF14520.6 KFM57964.1 - 0.00019 22.0 0.0 0.00074 20.1 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 KFM57964.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus EF-hand_3 PF09069.11 KFM57965.1 - 1.6e-39 134.2 0.0 1.1e-38 131.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand EF-hand_2 PF09068.11 KFM57965.1 - 2e-39 134.5 1.7 2.8e-39 134.0 0.6 1.9 2 0 0 2 2 1 1 EF hand Spectrin PF00435.21 KFM57965.1 - 7.4e-28 97.1 39.6 5.9e-09 36.4 0.4 5.9 5 1 0 5 5 5 4 Spectrin repeat ZZ PF00569.17 KFM57965.1 - 5.4e-17 61.3 7.8 1.3e-16 60.1 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type WW PF00397.26 KFM57965.1 - 4.3e-07 29.9 2.5 8.6e-07 28.9 2.5 1.5 1 0 0 1 1 1 1 WW domain C1_2 PF03107.16 KFM57965.1 - 1.3e-05 25.4 1.4 2.7e-05 24.4 1.4 1.5 1 0 0 1 1 1 1 C1 domain DUF3450 PF11932.8 KFM57965.1 - 0.0073 15.6 3.8 0.0073 15.6 3.8 3.6 3 2 1 4 4 4 1 Protein of unknown function (DUF3450) WXG100 PF06013.12 KFM57965.1 - 0.096 12.9 10.9 0.48 10.7 1.0 4.9 4 1 0 4 4 4 0 Proteins of 100 residues with WXG Acetyltransf_14 PF03421.16 KFM57965.1 - 0.1 12.6 0.5 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 YopJ Serine/Threonine acetyltransferase DUF948 PF06103.11 KFM57965.1 - 0.12 12.7 6.6 0.14 12.4 0.1 3.7 4 2 1 5 5 4 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 KFM57965.1 - 0.96 9.5 18.4 1.5 8.8 1.2 4.6 3 2 1 4 4 4 0 Laminin Domain II CdvA PF18822.1 KFM57965.1 - 1.8 8.4 8.9 1.3 8.9 0.4 4.5 4 1 0 4 4 4 0 CdvA-like coiled-coil domain SesA PF17107.5 KFM57965.1 - 3.2 8.0 7.0 29 4.9 0.1 4.5 3 1 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF16 PF01519.16 KFM57965.1 - 7.7 7.1 16.4 10 6.7 0.3 5.0 2 1 1 3 3 3 0 Protein of unknown function DUF16 DivIVA PF05103.13 KFM57965.1 - 8.2 6.5 9.2 2.4 8.2 0.8 3.6 3 0 0 3 3 3 0 DivIVA protein TRPM_tetra PF16519.5 KFM57965.1 - 8.4 6.6 11.8 12 6.1 1.0 4.3 5 1 0 5 5 4 0 Tetramerisation domain of TRPM ABC_tran PF00005.27 KFM57967.1 - 1.2e-51 174.8 0.0 4.9e-28 98.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFM57967.1 - 1.6e-43 149.4 13.2 1.7e-41 142.7 6.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KFM57967.1 - 9.6e-12 44.8 0.9 0.00016 21.2 0.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFM57967.1 - 2e-06 27.9 0.8 0.055 13.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFM57967.1 - 5.1e-06 27.0 1.3 0.034 14.5 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFM57967.1 - 2.8e-05 23.7 0.3 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM57967.1 - 3.9e-05 23.6 0.5 0.022 14.6 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase DUF87 PF01935.17 KFM57967.1 - 0.00024 21.3 1.6 0.31 11.1 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_25 PF13481.6 KFM57967.1 - 0.00039 20.0 0.4 0.048 13.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KFM57967.1 - 0.00055 20.0 2.5 0.0033 17.5 0.6 2.3 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 KFM57967.1 - 0.0026 18.0 1.9 1.5 9.1 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFM57967.1 - 0.0031 17.4 4.9 0.91 9.3 0.2 3.6 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFM57967.1 - 0.0037 17.8 0.1 2.1 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFM57967.1 - 0.0093 15.3 0.1 0.36 10.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 KFM57967.1 - 0.01 15.5 1.8 5.3 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 KFM57967.1 - 0.02 13.9 0.1 3.4 6.6 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 KFM57967.1 - 0.024 14.4 0.4 3.6 7.3 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 KFM57967.1 - 0.042 12.9 0.0 1.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF815 PF05673.13 KFM57967.1 - 0.07 12.3 0.3 6.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 KFM57967.1 - 0.086 11.7 0.2 8 5.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Lsm_C PF14894.6 KFM57967.1 - 0.13 12.0 0.4 0.42 10.4 0.4 1.8 1 0 0 1 1 1 0 Lsm C-terminal AAA_10 PF12846.7 KFM57967.1 - 0.15 10.9 0.8 0.77 8.6 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.12 KFM57967.1 - 1.2 9.1 4.5 0.93 9.4 0.1 2.7 3 0 0 3 3 3 0 NACHT domain ATP_bind_1 PF03029.17 KFM57967.1 - 2.7 7.7 4.8 45 3.7 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AMP-binding PF00501.28 KFM57968.1 - 7.4e-46 156.6 0.0 9.2e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM57968.1 - 5.8e-09 35.7 3.7 1.2e-08 34.7 3.7 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus ABC_membrane PF00664.23 KFM57969.1 - 1.5e-121 405.3 34.5 4.3e-67 226.6 13.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFM57969.1 - 2.4e-34 118.8 0.0 5.6e-34 117.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM57969.1 - 3e-06 26.8 0.8 0.00018 21.1 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFM57969.1 - 6.5e-06 26.1 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 KFM57969.1 - 0.00035 19.9 0.0 0.015 14.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KFM57969.1 - 0.00062 20.2 0.2 0.0027 18.1 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM57969.1 - 0.0013 19.0 0.0 0.0056 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KFM57969.1 - 0.0076 16.0 0.0 0.65 9.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 KFM57969.1 - 0.0081 15.0 0.1 0.025 13.4 0.0 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 KFM57969.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFM57969.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KFM57969.1 - 0.04 14.2 0.4 0.48 10.7 0.4 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KFM57969.1 - 0.049 14.2 0.8 2.4 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3094 PF11293.8 KFM57969.1 - 0.059 13.1 0.1 0.059 13.1 0.1 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF3094) UPF0542 PF15086.6 KFM57969.1 - 0.07 13.1 0.6 5.3 7.0 0.0 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 IstB_IS21 PF01695.17 KFM57969.1 - 0.079 12.7 0.2 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 KFM57969.1 - 0.12 12.4 0.2 0.69 10.0 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 KFM57969.1 - 0.13 12.3 0.1 4 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFM57969.1 - 0.15 12.2 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 KFM57973.1 - 1.9e-25 89.4 0.0 2.2e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM57973.1 - 4.3e-21 75.5 0.0 5.3e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM57973.1 - 3.2e-08 33.7 0.0 3.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM57973.1 - 0.00021 20.8 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFM57973.1 - 0.0043 16.2 0.1 0.0047 16.1 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFM57973.1 - 0.0045 16.4 0.1 0.0051 16.3 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase HI0933_like PF03486.14 KFM57973.1 - 0.005 15.6 1.0 0.0068 15.2 1.0 1.1 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.18 KFM57973.1 - 0.0062 16.4 0.1 0.0067 16.3 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFM57973.1 - 0.0094 15.0 0.1 0.0096 15.0 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KFM57973.1 - 0.014 16.0 0.1 0.021 15.4 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFM57973.1 - 0.017 15.3 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFM57973.1 - 0.017 14.5 0.1 0.019 14.3 0.1 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain B12-binding PF02310.19 KFM57973.1 - 0.034 14.2 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain HHH_5 PF14520.6 KFM57973.1 - 0.09 13.4 0.2 0.26 11.9 0.2 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix domain TIR PF01582.20 KFM57973.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 TIR domain TIR_2 PF13676.6 KFM57973.1 - 0.1 13.2 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 TIR domain zf-CCHC PF00098.23 KFM57974.1 - 0.13 12.4 2.1 0.13 12.4 2.1 3.1 5 0 0 5 5 5 0 Zinc knuckle zf-dskA_traR PF01258.17 KFM57974.1 - 0.74 9.8 5.2 5.7 7.0 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Zn_clus PF00172.18 KFM57974.1 - 1.8 8.7 11.5 2.1 8.5 4.5 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_H_Exchanger PF00999.21 KFM57977.1 - 1.4e-14 53.7 9.3 1.5e-14 53.6 9.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CitMHS PF03600.16 KFM57977.1 - 0.13 11.5 5.7 0.15 11.3 5.7 1.1 1 0 0 1 1 1 0 Citrate transporter DUF1129 PF06570.11 KFM57977.1 - 1.9 7.9 5.4 0.65 9.4 0.3 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1129) Topoisom_bac PF01131.20 KFM57979.1 - 7.7e-69 232.7 0.0 1e-68 232.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-C4_Topoisom PF01396.19 KFM57979.1 - 8.8e-11 41.4 0.2 8.8e-11 41.4 0.2 2.3 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Topoisom_bac PF01131.20 KFM57980.1 - 9.4e-24 84.2 0.0 9.9e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KFM57981.1 - 0.00039 20.6 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 Toprim domain DprA_WH PF17782.1 KFM57981.1 - 0.27 11.4 0.0 0.43 10.7 0.0 1.2 1 0 0 1 1 1 0 DprA winged helix domain DUF2040 PF09745.9 KFM57982.1 - 1.6e-32 112.1 21.6 2.4e-32 111.5 21.6 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) Stathmin PF00836.19 KFM57982.1 - 0.0032 17.4 14.6 0.0068 16.4 14.6 1.5 1 0 0 1 1 1 1 Stathmin family BRD4_CDT PF17105.5 KFM57982.1 - 0.0092 15.6 1.5 0.0092 15.6 1.5 2.4 2 0 0 2 2 2 1 C-terminal domain of bromodomain protein 4 DUF2315 PF10231.9 KFM57982.1 - 0.37 10.9 8.2 0.72 10.0 8.2 1.5 1 1 0 1 1 1 0 Apoptogenic protein 1 DUF3306 PF11748.8 KFM57982.1 - 0.81 10.6 10.3 0.18 12.7 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) HisK_N PF09385.10 KFM57984.1 - 0.0022 18.0 0.0 0.0025 17.8 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase N terminal DUF573 PF04504.14 KFM57984.1 - 0.026 15.2 0.4 0.047 14.4 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF573 60KD_IMP PF02096.20 KFM57984.1 - 0.09 12.7 0.3 0.12 12.3 0.2 1.3 1 1 0 1 1 1 0 60Kd inner membrane protein DUF5613 PF18467.1 KFM57984.1 - 0.11 12.9 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) Zip PF02535.22 KFM57985.1 - 1.4e-45 156.0 9.2 1.7e-45 155.7 9.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter BRCT_2 PF16589.5 KFM57986.1 - 6.3e-10 39.3 0.6 7.3e-09 35.9 0.0 2.8 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFM57986.1 - 0.0013 19.0 0.0 0.0058 17.0 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFM57986.1 - 0.079 13.3 0.1 0.31 11.4 0.1 2.0 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DNA_pol_B_thumb PF14791.6 KFM57987.1 - 6.2e-13 48.7 0.0 9.1e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KFM57987.1 - 8.4e-13 48.5 0.0 1.4e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase beta palm DDE_3 PF13358.6 KFM57988.1 - 8e-08 32.2 0.0 1.6e-07 31.2 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Cornichon PF03311.14 KFM57989.1 - 1e-48 164.7 6.9 1.2e-48 164.4 6.9 1.0 1 0 0 1 1 1 1 Cornichon protein KASH PF10541.9 KFM57989.1 - 0.41 10.9 3.5 4.9 7.5 0.4 2.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain FGGY_N PF00370.21 KFM57990.1 - 5.5e-75 252.1 0.9 1.6e-74 250.5 0.4 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFM57990.1 - 2.1e-66 223.5 0.4 3.6e-66 222.7 0.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain His_Phos_1 PF00300.22 KFM57992.1 - 2.3e-11 43.7 0.0 4.8e-07 29.7 0.0 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF1917 PF08939.10 KFM57993.1 - 0.0046 16.9 0.6 0.021 14.8 0.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) DUF228 PF02989.14 KFM57995.1 - 0.14 12.0 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Lyme disease proteins of unknown function Oxysterol_BP PF01237.18 KFM57997.1 - 1.2e-92 310.7 0.1 2.2e-90 303.2 0.1 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Tetraspanin PF00335.20 KFM57999.1 - 1.7e-45 155.6 12.5 2e-45 155.3 12.5 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 KFM57999.1 - 0.0013 18.8 4.2 0.0013 18.8 4.2 2.1 2 1 0 2 2 2 1 CD20-like family CCG PF02754.16 KFM57999.1 - 3.2 8.0 6.7 1.9 8.7 0.3 3.2 2 1 2 4 4 4 0 Cysteine-rich domain Tetraspanin PF00335.20 KFM58000.1 - 9.3e-22 77.9 1.0 1e-21 77.7 1.0 1.0 1 0 0 1 1 1 1 Tetraspanin family S4 PF01479.25 KFM58001.1 - 3.9e-09 36.1 2.0 3.9e-09 36.1 2.0 2.0 2 0 0 2 2 2 1 S4 domain DUF4381 PF14316.6 KFM58001.1 - 0.18 12.0 1.2 0.28 11.4 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) 3Beta_HSD PF01073.19 KFM58002.1 - 2.5e-08 33.3 0.0 4.6e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KFM58002.1 - 3.4e-08 33.3 0.0 6.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KFM58002.1 - 7e-08 31.9 0.1 9.4e-07 28.2 0.1 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFM58002.1 - 2.2e-07 31.0 0.0 3.6e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFM58002.1 - 3.6e-07 29.9 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFM58002.1 - 0.0013 18.0 1.0 0.96 8.6 0.1 3.1 2 1 0 2 2 2 1 Male sterility protein Phage_P2_GpE PF06528.12 KFM58002.1 - 0.12 12.0 1.9 0.15 11.7 0.2 2.0 2 0 0 2 2 2 0 Phage P2 GpE NHR2 PF08788.11 KFM58002.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 NHR2 domain like TatD_DNase PF01026.21 KFM58002.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 TatD related DNase adh_short PF00106.25 KFM58002.1 - 0.21 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Ras PF00071.22 KFM58003.1 - 6.1e-15 55.2 0.0 6.7e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM58003.1 - 3.6e-12 46.6 0.0 4e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFM58003.1 - 0.003 17.6 0.0 0.0032 17.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KFM58003.1 - 0.006 16.3 0.0 0.006 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFM58003.1 - 0.032 14.0 0.1 0.049 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 KFM58003.1 - 0.034 13.6 0.1 0.038 13.4 0.1 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFM58003.1 - 0.048 13.1 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein Arf PF00025.21 KFM58003.1 - 0.05 13.0 0.1 0.054 12.9 0.1 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFM58003.1 - 0.065 13.1 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KFM58003.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain DDE_Tnp_IS1595 PF12762.7 KFM58004.1 - 1.5e-07 31.6 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF1533 PF07550.11 KFM58004.1 - 0.085 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Retrotran_gag_2 PF14223.6 KFM58006.1 - 0.00064 19.4 0.0 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Cadherin PF00028.17 KFM58007.1 - 1.4e-249 807.6 38.7 4.2e-21 75.2 0.0 19.3 19 0 0 19 19 19 19 Cadherin domain Cadherin_2 PF08266.12 KFM58007.1 - 7e-15 54.6 2.3 0.86 9.5 0.0 9.9 11 0 0 11 11 11 5 Cadherin-like Cadherin_3 PF16184.5 KFM58007.1 - 1.6e-12 47.4 23.5 0.065 13.2 0.0 13.0 14 1 0 14 14 14 5 Cadherin-like Cadherin_pro PF08758.11 KFM58007.1 - 3.4e-11 43.1 2.5 0.1 12.8 0.6 7.1 7 0 0 7 7 7 3 Cadherin prodomain like fn3 PF00041.21 KFM58007.1 - 0.00031 21.0 0.4 1.8 9.0 0.0 5.4 5 0 0 5 5 5 1 Fibronectin type III domain SUKH-4 PF14435.6 KFM58007.1 - 0.0035 17.4 0.3 3.4 7.7 0.0 4.2 5 0 0 5 5 5 1 SUKH-4 immunity protein DUF3481 PF11980.8 KFM58007.1 - 0.019 14.7 0.4 0.059 13.1 0.2 1.9 1 1 1 2 2 2 0 C-terminal domain of neuropilin glycoprotein Cadherin PF00028.17 KFM58008.1 - 8.3e-101 330.7 6.4 5.5e-17 62.0 0.0 8.1 8 0 0 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 KFM58008.1 - 1.6e-12 47.0 0.0 0.1 12.4 0.1 6.7 7 0 0 7 7 7 3 Cadherin-like Cadherin_3 PF16184.5 KFM58008.1 - 2.3e-08 34.0 18.1 0.073 13.1 0.1 7.4 9 1 0 9 9 9 3 Cadherin-like Big_9 PF17963.1 KFM58008.1 - 0.012 16.3 18.3 0.76 10.6 0.2 5.4 5 0 0 5 5 5 0 Bacterial Ig domain CK2S PF15011.6 KFM58010.1 - 1.7e-07 31.3 2.5 2.2e-07 30.9 1.3 1.7 1 1 1 2 2 2 1 Casein Kinase 2 substrate SWIRM PF04433.17 KFM58010.1 - 0.056 13.8 1.6 0.084 13.2 0.2 2.0 2 0 0 2 2 2 0 SWIRM domain Cas_DxTHG PF09455.10 KFM58010.1 - 0.13 11.8 5.6 0.15 11.6 5.6 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family I-set PF07679.16 KFM58011.1 - 0.0001 22.3 0.1 0.00015 21.7 0.1 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM58011.1 - 0.078 13.6 0.0 0.097 13.3 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain PRIMA1 PF16101.5 KFM58012.1 - 0.15 12.1 4.7 0.18 11.9 4.7 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Calcipressin PF04847.12 KFM58012.1 - 2.9 7.6 7.9 2.5 7.8 6.7 1.5 2 0 0 2 2 2 0 Calcipressin TAT_signal PF10518.9 KFM58013.1 - 0.12 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence I-set PF07679.16 KFM58014.1 - 1.4e-29 102.0 0.0 2.8e-14 53.0 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM58014.1 - 8.7e-28 96.7 0.1 1.4e-11 44.8 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFM58014.1 - 1.6e-18 66.6 0.0 8.9e-08 32.2 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM58014.1 - 8.6e-18 64.5 0.0 2.5e-08 34.1 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain EF-hand_6 PF13405.6 KFM58014.1 - 2e-07 30.4 0.2 0.031 14.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFM58014.1 - 2.7e-07 29.7 0.1 0.0094 15.4 0.0 2.8 2 0 0 2 2 2 2 EF hand V-set PF07686.17 KFM58014.1 - 6.7e-07 29.5 1.5 0.17 12.1 0.1 4.8 3 2 0 3 3 3 2 Immunoglobulin V-set domain EF-hand_7 PF13499.6 KFM58014.1 - 6.2e-05 23.4 0.3 0.00014 22.2 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM58014.1 - 0.0026 17.2 0.0 0.94 9.1 0.0 2.6 2 0 0 2 2 2 1 EF hand C2-set_2 PF08205.12 KFM58014.1 - 0.0036 17.4 0.0 2.1 8.5 0.0 2.9 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain EF-hand_8 PF13833.6 KFM58014.1 - 0.0063 16.3 0.4 0.32 10.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair Ig_5 PF16681.5 KFM58014.1 - 0.029 14.8 0.0 0.96 9.9 0.0 2.9 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Caleosin PF05042.13 KFM58014.1 - 0.032 14.2 0.4 3.3 7.6 0.1 2.7 3 0 0 3 3 3 0 Caleosin related protein Ig_4 PF16680.5 KFM58014.1 - 0.033 14.4 0.0 12 6.3 0.0 3.0 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFM58014.1 - 0.048 13.7 0.1 2.3 8.3 0.0 3.0 3 1 0 3 3 3 0 C17orf99 Ig domain SPARC_Ca_bdg PF10591.9 KFM58014.1 - 0.091 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region RasGEF PF00617.19 KFM58016.1 - 9.2e-51 172.5 0.5 1.7e-50 171.7 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain PDZ PF00595.24 KFM58016.1 - 4.5e-11 43.0 0.0 1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM58016.1 - 5.4e-11 42.2 0.0 1.5e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain RasGEF_N PF00618.20 KFM58016.1 - 1.2e-10 41.5 1.3 1.1e-08 35.2 1.3 2.5 1 1 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFM58016.1 - 1.6e-10 41.5 0.1 4e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain cNMP_binding PF00027.29 KFM58016.1 - 0.0004 20.4 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PDZ_2 PF13180.6 KFM58016.1 - 0.0028 18.0 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain DUF5314 PF17241.2 KFM58016.1 - 0.22 11.2 0.7 5.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5314) CcdA PF07362.12 KFM58017.1 - 0.015 15.7 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA Lyx_isomer PF07385.12 KFM58017.1 - 0.024 13.9 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 D-lyxose isomerase DUF1759 PF03564.15 KFM58018.1 - 2.5e-26 92.4 0.3 6.1e-26 91.1 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM58018.1 - 8.4e-14 51.7 0.3 1.8e-13 50.6 0.3 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF3696 PF12476.8 KFM58018.1 - 0.016 15.6 0.1 0.056 13.9 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3696) RIG-I_C-RD PF11648.8 KFM58018.1 - 0.1 12.8 0.1 0.56 10.5 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I Retrotran_gag_2 PF14223.6 KFM58020.1 - 8.9e-21 74.0 5.0 1.7e-20 73.1 5.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KFM58020.1 - 5.1e-08 32.7 1.3 1.8e-07 30.9 0.2 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain I_LWEQ PF01608.17 KFM58022.1 - 0.07 13.4 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 I/LWEQ domain Snf7 PF03357.21 KFM58023.1 - 2.4e-16 59.8 12.0 3.6e-16 59.2 12.0 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KFM58023.1 - 5.4e-05 23.2 6.2 7.7e-05 22.7 6.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 KFM58023.1 - 0.015 14.9 0.2 0.05 13.2 0.1 1.9 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase DUF4363 PF14276.6 KFM58023.1 - 0.049 13.8 4.5 2.4 8.3 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) DUF1843 PF08898.10 KFM58023.1 - 0.19 12.2 0.1 0.19 12.2 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) DUF1993 PF09351.10 KFM58023.1 - 0.21 11.7 2.2 1 9.5 1.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) TMEM215 PF15746.5 KFM58023.1 - 1.5 8.3 4.8 1.5 8.2 0.4 2.0 1 1 1 2 2 2 0 TMEM215 family Cytochrom_B562 PF07361.11 KFM58023.1 - 1.5 9.5 10.2 3.2 8.5 3.3 2.8 2 2 0 2 2 2 0 Cytochrome b562 DDE_3 PF13358.6 KFM58024.1 - 8.7e-23 80.7 0.0 1.9e-13 50.4 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58024.1 - 2.5e-16 59.7 2.2 5.1e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase PhetRS_B1 PF18262.1 KFM58024.1 - 0.18 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain HTH_Tnp_Tc3_2 PF01498.18 KFM58025.1 - 5.5e-16 58.6 3.5 6.1e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58025.1 - 1.4e-13 50.9 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58025.1 - 3.1e-07 30.0 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58025.1 - 0.0029 17.4 0.6 0.008 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58025.1 - 2.3 8.9 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain COesterase PF00135.28 KFM58027.1 - 2.4e-61 208.2 0.1 2.9e-61 207.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM58027.1 - 0.0094 15.8 0.1 0.53 10.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold HTH_Tnp_Tc3_2 PF01498.18 KFM58029.1 - 4.5e-16 58.8 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58029.1 - 7.4e-14 51.7 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58029.1 - 2.1e-07 30.6 1.4 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58029.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58029.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM58030.1 - 2.3e-08 33.7 0.6 2.3e-08 33.7 0.6 1.0 1 0 0 1 1 1 1 Transposase IS4 WD40 PF00400.32 KFM58031.1 - 0.00017 22.3 0.5 0.00017 22.3 0.5 3.5 3 1 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM58032.1 - 0.053 13.8 0.0 0.25 11.7 0.0 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 KFM58033.1 - 5.6e-06 26.7 6.5 0.00025 21.4 0.3 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM58033.1 - 2.2e-05 23.6 3.8 0.022 14.3 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFM58033.1 - 0.00012 21.7 5.3 0.39 10.8 0.1 4.5 4 1 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 KFM58033.1 - 0.00077 19.3 1.1 0.13 12.1 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM58033.1 - 0.096 12.2 1.1 0.56 9.8 0.0 2.9 4 0 0 4 4 4 0 EF hand Sigma70_r1_1 PF03979.14 KFM58033.1 - 0.14 12.3 0.0 0.42 10.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 HlyIII PF03006.20 KFM58034.1 - 1.1e-05 25.3 0.6 1.4e-05 24.9 0.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.20 KFM58035.1 - 1.5e-25 90.2 7.2 1.7e-25 90.0 7.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related TauD PF02668.16 KFM58036.1 - 2.1e-33 116.3 0.0 1e-32 114.0 0.0 1.8 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFM58036.1 - 2.2e-13 50.7 0.1 4.2e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KFM58036.1 - 0.0012 18.0 0.1 0.0058 15.8 0.0 1.9 2 0 0 2 2 2 1 CsiD DLIC PF05783.11 KFM58040.1 - 6.6e-111 371.4 0.6 2.6e-110 369.5 0.6 1.8 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) HTH_38 PF13936.6 KFM58041.1 - 4.2e-08 32.8 5.9 4.3e-08 32.8 0.1 3.1 3 1 0 3 3 3 1 Helix-turn-helix domain DDE_3 PF13358.6 KFM58041.1 - 1.5e-05 24.8 0.0 4.1e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_1 PF11427.8 KFM58041.1 - 6.2e-05 22.8 0.1 0.00012 21.9 0.1 1.5 1 0 0 1 1 1 1 Tc3 transposase HTH_Tnp_Tc3_2 PF01498.18 KFM58041.1 - 0.0036 17.5 0.7 0.0036 17.5 0.7 2.1 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM58041.1 - 0.071 13.7 1.4 1.4 9.6 0.0 3.2 2 2 0 3 3 3 0 Homeodomain-like domain Destabilase PF05497.12 KFM58042.1 - 2e-38 131.4 8.4 2.3e-38 131.1 8.4 1.1 1 0 0 1 1 1 1 Destabilase Varsurf_PPLC PF03490.13 KFM58043.1 - 0.00014 21.8 0.0 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C zf-DNA_Pol PF08996.10 KFM58043.1 - 0.059 13.1 0.1 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Peptidase_S49 PF01343.18 KFM58044.1 - 0.12 12.3 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 ATP-synt_ab PF00006.25 KFM58045.1 - 9.2e-63 211.7 0.0 1.4e-62 211.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFM58045.1 - 3.6e-22 78.7 0.7 8.3e-22 77.5 0.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KFM58045.1 - 0.0038 16.5 0.1 0.006 15.8 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 KFM58045.1 - 0.0039 17.1 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KFM58045.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KFM58045.1 - 0.045 14.1 0.1 0.15 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KFM58045.1 - 0.094 13.0 0.2 0.25 11.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFM58045.1 - 0.12 11.6 0.1 0.27 10.4 0.1 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KFM58045.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KFM58045.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PDEase_I PF00233.19 KFM58046.1 - 8.6e-76 254.8 5.0 1.6e-75 253.9 5.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF1948 PF09185.10 KFM58046.1 - 0.096 12.6 0.2 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Ornatin PF02088.15 KFM58047.1 - 0.00017 21.3 0.2 0.00024 20.8 0.2 1.2 1 0 0 1 1 1 1 Ornatin VPS9 PF02204.18 KFM58047.1 - 0.061 13.5 1.2 0.082 13.1 0.3 1.7 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain RVT_1 PF00078.27 KFM58048.1 - 1.5e-05 24.6 0.0 1.6e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SGL PF08450.12 KFM58049.1 - 2.2e-67 227.2 0.0 2.6e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Ntox37 PF15535.6 KFM58049.1 - 0.04 14.3 0.0 0.67 10.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial toxin 37 Reg_prop PF07494.11 KFM58049.1 - 0.052 13.8 0.3 12 6.5 0.0 3.4 3 0 0 3 3 3 0 Two component regulator propeller SL4P PF17618.2 KFM58049.1 - 0.14 12.2 0.0 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein EF-hand_7 PF13499.6 KFM58050.1 - 7.4e-17 61.6 19.8 1.4e-06 28.6 1.4 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 KFM58050.1 - 1.2e-16 58.9 21.1 0.0017 17.8 0.0 7.2 6 1 1 7 7 7 6 EF hand EF-hand_6 PF13405.6 KFM58050.1 - 7.5e-13 47.3 19.1 0.031 14.2 0.1 7.5 7 0 0 7 7 7 5 EF-hand domain EF-hand_5 PF13202.6 KFM58050.1 - 1.2e-12 46.7 30.4 9.2e-05 21.8 0.2 7.2 8 0 0 8 8 8 5 EF hand EF-hand_8 PF13833.6 KFM58050.1 - 4.1e-08 32.9 12.3 0.52 10.2 0.0 5.8 4 2 1 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM58050.1 - 1.4e-07 31.8 12.2 0.041 14.2 1.6 3.2 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFM58050.1 - 0.0019 18.0 1.5 2.4 8.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 KFM58050.1 - 3.1 7.8 11.0 33 4.5 0.4 4.2 3 2 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand CUB PF00431.20 KFM58051.1 - 4.9e-21 75.1 0.0 6e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 CUB domain BCD PF15461.6 KFM58053.1 - 0.041 13.4 10.5 0.4 10.1 0.3 2.1 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase DUF5418 PF17439.2 KFM58053.1 - 6.8 6.8 13.0 0.081 13.0 2.9 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5418) HTH_Tnp_Tc3_2 PF01498.18 KFM58054.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58054.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58054.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58054.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58054.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain PIRT PF15099.6 KFM58055.1 - 0.056 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family NeuB PF03102.14 KFM58056.1 - 2.6e-74 249.7 0.0 3.1e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 KFM58056.1 - 0.02 15.5 0.0 0.048 14.3 0.0 1.7 1 0 0 1 1 1 0 SAF domain AAA PF00004.29 KFM58058.1 - 1.8e-35 122.3 0.0 2.8e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM58058.1 - 7.2e-11 41.7 0.3 1.5e-10 40.7 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KFM58058.1 - 1.6e-05 24.9 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM58058.1 - 1.9e-05 25.1 0.3 0.00058 20.3 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFM58058.1 - 2.7e-05 23.9 0.0 0.0001 22.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFM58058.1 - 3.7e-05 24.0 0.1 0.0034 17.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFM58058.1 - 5.6e-05 23.1 0.1 0.00046 20.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 KFM58058.1 - 0.00076 18.9 0.0 1 8.7 0.0 2.5 1 1 1 2 2 2 2 Bacterial TniB protein AAA_33 PF13671.6 KFM58058.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFM58058.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 KFM58058.1 - 0.0014 18.6 0.1 0.0074 16.2 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain DUF815 PF05673.13 KFM58058.1 - 0.0028 16.8 0.0 0.0061 15.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KFM58058.1 - 0.0031 17.1 0.2 0.019 14.5 0.2 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFM58058.1 - 0.0036 17.1 0.0 0.012 15.3 0.0 1.9 1 1 1 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFM58058.1 - 0.0047 16.3 0.1 0.011 15.1 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KFM58058.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 KFM58058.1 - 0.019 14.2 0.1 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KFM58058.1 - 0.032 13.9 0.0 0.058 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM58058.1 - 0.036 14.0 0.1 0.17 11.8 0.1 2.0 1 1 1 2 2 2 0 NACHT domain TsaE PF02367.17 KFM58058.1 - 0.037 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFM58058.1 - 0.04 14.3 0.0 0.079 13.4 0.0 1.6 1 1 0 1 1 1 0 RNA helicase Hydin_ADK PF17213.3 KFM58058.1 - 0.046 14.0 0.6 1.7 8.9 0.0 2.5 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 KFM58058.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFM58058.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KFM58058.1 - 0.08 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KFM58058.1 - 0.083 12.5 0.0 0.87 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KFM58058.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 KFM58058.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase ABC_tran PF00005.27 KFM58058.1 - 0.13 12.8 0.0 0.59 10.6 0.0 2.1 2 1 0 2 2 2 0 ABC transporter EGF PF00008.27 KFM58059.1 - 1e-05 25.7 14.5 0.0088 16.3 8.2 2.6 2 1 0 2 2 2 2 EGF-like domain EGF_3 PF12947.7 KFM58059.1 - 0.045 14.0 0.6 0.045 14.0 0.6 2.5 2 0 0 2 2 2 0 EGF domain Defensin_like PF10868.8 KFM58059.1 - 0.051 14.3 11.0 0.14 12.9 11.1 1.8 1 1 0 1 1 1 0 Cysteine-rich antifungal protein 2, defensin-like DUF2970 PF11174.8 KFM58059.1 - 0.21 11.5 4.1 0.31 10.9 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) EGF_2 PF07974.13 KFM58059.1 - 1 9.8 16.8 0.082 13.3 8.4 2.9 2 1 0 2 2 2 0 EGF-like domain hEGF PF12661.7 KFM58059.1 - 5.2 7.8 20.9 0.3 11.8 5.4 3.8 4 1 0 4 4 4 0 Human growth factor-like EGF EGF PF00008.27 KFM58060.1 - 4.3e-29 100.4 75.9 1.4e-09 38.1 7.0 8.4 7 0 0 7 7 7 5 EGF-like domain Ephrin_rec_like PF07699.13 KFM58060.1 - 2.8e-20 71.8 14.8 9.1e-12 44.6 6.0 4.4 3 0 0 3 3 2 2 Putative ephrin-receptor like hEGF PF12661.7 KFM58060.1 - 9.8e-14 51.4 27.7 2.7e-07 30.9 7.2 8.9 10 0 0 10 10 9 5 Human growth factor-like EGF HYR PF02494.16 KFM58060.1 - 6.6e-13 48.8 0.0 1.7e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 HYR domain Laminin_G_3 PF13385.6 KFM58060.1 - 9.8e-13 48.5 0.3 1.7e-12 47.8 0.3 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 KFM58060.1 - 6.7e-07 29.6 82.2 0.0032 17.8 11.1 8.2 7 0 0 7 7 7 4 EGF-like domain EGF_3 PF12947.7 KFM58060.1 - 4.3e-06 26.8 57.6 0.025 14.8 4.0 7.4 6 1 0 6 6 6 4 EGF domain Laminin_G_2 PF02210.24 KFM58060.1 - 2.8e-05 24.7 0.0 5.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM58060.1 - 0.0006 20.0 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain EGF_CA PF07645.15 KFM58060.1 - 0.0012 18.9 8.7 0.0012 18.9 8.7 7.5 4 1 3 7 7 5 3 Calcium-binding EGF domain TNFR_c6 PF00020.18 KFM58060.1 - 0.03 14.7 20.1 0.83 10.1 0.2 7.0 4 2 2 6 6 6 0 TNFR/NGFR cysteine-rich region Pentaxin PF00354.17 KFM58060.1 - 0.036 13.7 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Pentaxin family EGF PF00008.27 KFM58061.1 - 7.7e-10 38.9 21.9 1.7e-07 31.4 9.7 3.4 3 1 0 3 3 3 2 EGF-like domain EGF_3 PF12947.7 KFM58061.1 - 7.2e-05 22.9 12.5 0.0046 17.1 2.4 3.0 3 0 0 3 3 3 2 EGF domain hEGF PF12661.7 KFM58061.1 - 0.00022 21.8 4.9 0.00022 21.8 4.9 3.7 4 1 0 4 4 4 1 Human growth factor-like EGF EGF_2 PF07974.13 KFM58061.1 - 0.00044 20.6 17.9 0.046 14.1 1.7 2.5 2 0 0 2 2 2 2 EGF-like domain EGF_CA PF07645.15 KFM58061.1 - 0.0018 18.4 16.3 0.21 11.8 9.4 2.8 1 1 1 2 2 2 2 Calcium-binding EGF domain Laminin_EGF PF00053.24 KFM58061.1 - 0.0022 18.1 14.5 0.06 13.5 1.9 2.4 1 1 1 2 2 2 2 Laminin EGF domain FXa_inhibition PF14670.6 KFM58061.1 - 0.0099 16.1 3.4 0.0099 16.1 3.4 2.8 2 1 1 3 3 3 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFM58061.1 - 0.25 11.3 0.4 0.25 11.3 0.4 3.2 4 1 0 4 4 4 0 Complement Clr-like EGF-like DSL PF01414.19 KFM58061.1 - 0.51 10.6 9.5 1.1 9.5 9.5 1.6 1 1 0 1 1 1 0 Delta serrate ligand EGF_alliinase PF04863.13 KFM58061.1 - 0.6 10.6 14.3 0.76 10.2 0.8 3.0 2 1 1 3 3 3 0 Alliinase EGF-like domain Ephrin_rec_like PF07699.13 KFM58062.1 - 2.7e-37 126.3 36.3 4.4e-14 52.0 4.3 4.8 4 1 1 5 5 5 4 Putative ephrin-receptor like HYR PF02494.16 KFM58062.1 - 4.5e-07 30.1 8.7 3.2e-06 27.4 0.4 3.2 3 0 0 3 3 3 2 HYR domain NCD3G PF07562.14 KFM58062.1 - 8e-05 22.5 36.6 0.093 12.7 0.8 5.9 3 1 4 7 7 7 5 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 KFM58062.1 - 0.026 14.9 32.3 0.48 10.9 2.6 6.9 5 2 0 5 5 5 0 TNFR/NGFR cysteine-rich region Sushi PF00084.20 KFM58063.1 - 2.3e-22 79.4 10.5 9.6e-12 45.3 0.1 3.8 4 0 0 4 4 4 3 Sushi repeat (SCR repeat) F5_F8_type_C PF00754.25 KFM58063.1 - 0.0011 19.1 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain HRM PF02793.22 KFM58063.1 - 0.051 13.9 1.0 8.8 6.7 0.1 3.2 3 0 0 3 3 3 0 Hormone receptor domain Sushi PF00084.20 KFM58064.1 - 4.9e-32 110.3 18.8 1.5e-11 44.7 0.2 4.9 5 0 0 5 5 5 3 Sushi repeat (SCR repeat) EGF_CA PF07645.15 KFM58064.1 - 7.9e-08 32.4 9.7 7.9e-08 32.4 9.7 2.8 3 0 0 3 3 3 1 Calcium-binding EGF domain F5_F8_type_C PF00754.25 KFM58064.1 - 1.7e-05 24.9 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain hEGF PF12661.7 KFM58064.1 - 0.0035 17.9 5.6 0.0097 16.5 1.2 3.8 2 0 0 2 2 2 1 Human growth factor-like EGF cEGF PF12662.7 KFM58064.1 - 0.0057 16.6 17.3 0.06 13.3 0.4 4.6 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFM58064.1 - 0.079 13.2 8.4 0.09 13.0 5.5 2.6 2 0 0 2 2 2 0 EGF domain FXa_inhibition PF14670.6 KFM58064.1 - 2.1 8.7 14.3 0.072 13.4 5.7 2.8 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site CUB PF00431.20 KFM58065.1 - 5.3e-41 139.4 0.0 9.2e-19 67.8 0.1 3.0 3 0 0 3 3 3 3 CUB domain CUB_2 PF02408.20 KFM58065.1 - 0.00085 19.1 0.0 3 7.6 0.0 3.3 3 0 0 3 3 3 2 CUB-like domain zf-RING_2 PF13639.6 KFM58066.1 - 4.7e-14 52.4 4.2 9.3e-14 51.5 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFM58066.1 - 2.1e-12 46.5 0.9 5.9e-12 45.1 0.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFM58066.1 - 6.5e-09 35.5 4.1 1.2e-08 34.6 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM58066.1 - 7.6e-09 35.3 4.1 7.6e-09 35.3 4.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM58066.1 - 3.8e-08 33.2 2.5 7.8e-08 32.2 2.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFM58066.1 - 1.2e-07 31.9 6.6 5.3e-07 29.8 6.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM58066.1 - 2.9e-06 27.2 0.9 2.9e-06 27.2 0.9 2.3 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM58066.1 - 1.4e-05 24.8 2.6 3e-05 23.8 2.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFM58066.1 - 2e-05 24.4 3.7 4e-05 23.4 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KFM58066.1 - 9.4e-05 22.4 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-ANAPC11 PF12861.7 KFM58066.1 - 0.0013 18.7 4.0 0.0024 17.9 3.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KFM58066.1 - 0.02 14.8 3.3 0.041 13.8 3.3 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 KFM58066.1 - 0.037 14.1 2.2 0.13 12.4 2.2 2.0 1 1 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 KFM58066.1 - 0.093 12.4 2.9 0.2 11.3 2.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Cadherin_C_2 PF16492.5 KFM58066.1 - 0.095 13.5 0.1 0.35 11.7 0.1 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RINGv PF12906.7 KFM58066.1 - 0.12 12.6 4.0 0.25 11.5 4.0 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KFM58066.1 - 0.14 12.4 4.9 1.9 8.7 4.9 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFM58066.1 - 0.23 11.3 5.0 0.55 10.1 5.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Profilin PF00235.19 KFM58067.1 - 1.8e-37 128.4 0.1 2e-37 128.3 0.1 1.0 1 0 0 1 1 1 1 Profilin DUF1053 PF06327.14 KFM58068.1 - 0.0066 17.0 0.3 0.0087 16.6 0.3 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) Pkinase PF00069.25 KFM58069.1 - 3.7e-24 85.5 0.0 4.8e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM58069.1 - 3.7e-11 42.8 0.0 5.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFM58069.1 - 1.2e-08 35.5 0.2 4e-08 33.8 0.0 2.0 2 1 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KFM58070.1 - 2.5e-21 75.9 0.1 3.7e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 C2 domain DnaJ_C PF01556.18 KFM58071.1 - 2.6e-33 115.2 0.3 3.5e-33 114.8 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFM58071.1 - 1.1e-28 99.1 7.5 1.9e-28 98.3 7.5 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KFM58071.1 - 0.035 14.0 0.2 0.072 13.0 0.2 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein HTH_10 PF04967.12 KFM58071.1 - 0.12 12.2 0.0 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain NfI_DNAbd_pre-N PF10524.9 KFM58072.1 - 1.5e-24 85.5 2.6 2.9e-24 84.6 2.6 1.5 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.16 KFM58072.1 - 2.3e-13 50.2 0.3 6.6e-13 48.8 0.3 1.8 1 0 0 1 1 1 1 MH1 domain Jun PF03957.13 KFM58074.1 - 4.9e-21 75.7 1.6 1.1e-20 74.5 1.6 1.6 1 1 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.21 KFM58074.1 - 1.1e-16 60.7 15.7 1.8e-16 59.9 15.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFM58074.1 - 1.4e-07 31.9 9.3 3.1e-07 30.8 9.3 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KFM58074.1 - 1.8e-06 27.9 15.6 5.7e-06 26.3 15.6 1.8 1 1 0 1 1 1 1 Basic region leucine zipper Jnk-SapK_ap_N PF09744.9 KFM58074.1 - 0.0081 16.4 4.2 0.015 15.5 4.2 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 PspA_IM30 PF04012.12 KFM58074.1 - 0.011 15.4 0.6 0.016 14.8 0.6 1.2 1 0 0 1 1 1 0 PspA/IM30 family ZapB PF06005.12 KFM58074.1 - 0.034 14.6 3.0 0.034 14.6 3.0 2.1 1 1 1 2 2 2 0 Cell division protein ZapB HMMR_C PF15908.5 KFM58074.1 - 0.053 13.8 1.0 0.053 13.8 1.0 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Phlebovirus_NSM PF07246.11 KFM58074.1 - 0.079 12.3 1.7 1.1 8.5 2.7 2.1 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M ADIP PF11559.8 KFM58074.1 - 0.13 12.3 6.9 0.27 11.3 6.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 KFM58074.1 - 0.16 12.4 0.6 0.37 11.2 0.6 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 KFM58074.1 - 0.9 9.3 3.5 1.9 8.3 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 KFM58074.1 - 1.1 9.9 6.3 0.13 12.9 1.2 2.1 2 0 0 2 2 2 0 SlyX DUF1664 PF07889.12 KFM58074.1 - 1.4 9.0 4.6 0.71 9.9 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KFM58074.1 - 7.1 7.3 9.1 5.3 7.7 2.0 2.7 2 1 1 3 3 3 0 Initiation control protein YabA DivIC PF04977.15 KFM58074.1 - 8.4 6.2 8.9 1.3 8.8 2.7 2.3 1 1 1 2 2 2 0 Septum formation initiator RGS PF00615.19 KFM58075.1 - 2.9e-24 85.6 0.3 3.3e-24 85.4 0.3 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain HTH_Tnp_Tc3_2 PF01498.18 KFM58076.1 - 1.7e-14 53.8 1.7 3.7e-14 52.7 1.7 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58076.1 - 1.3e-10 41.2 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM58076.1 - 0.001 19.6 7.3 0.003 18.2 1.1 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_20 PF12840.7 KFM58076.1 - 0.013 15.5 0.0 0.24 11.5 0.0 2.7 3 1 0 3 3 3 0 Helix-turn-helix domain FUR PF01475.19 KFM58076.1 - 0.043 14.0 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family DUF4524 PF15025.6 KFM58076.1 - 0.27 11.0 2.2 1.7 8.4 1.8 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4524) Peroxin-13_N PF04088.13 KFM58077.1 - 9.5e-41 139.5 0.1 1.3e-40 139.0 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 KFM58077.1 - 0.00048 19.7 0.0 0.00089 18.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM58077.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Sun2_CC2 PF18580.1 KFM58078.1 - 0.11 12.7 0.1 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Peptidase_M13_N PF05649.13 KFM58079.1 - 9.7e-41 140.7 0.2 1.3e-40 140.3 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM58079.1 - 1.1e-24 87.2 0.0 1.6e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 LRR_8 PF13855.6 KFM58080.1 - 0.011 15.5 0.3 0.018 14.8 0.3 1.5 1 1 0 1 1 1 0 Leucine rich repeat HEAT_2 PF13646.6 KFM58081.1 - 6.2e-05 23.3 0.0 0.0001 22.6 0.0 1.3 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 KFM58081.1 - 0.0021 18.2 0.0 0.69 10.3 0.0 2.5 2 0 0 2 2 2 2 HEAT repeat HEAT PF02985.22 KFM58083.1 - 0.013 15.7 0.8 1.2 9.6 0.0 2.9 2 1 1 3 3 3 0 HEAT repeat BLM10_mid PF16507.5 KFM58083.1 - 0.022 13.4 0.0 0.025 13.3 0.0 1.0 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region CDT1_C PF16679.5 KFM58083.1 - 0.09 13.2 0.0 0.093 13.2 0.0 1.1 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain YvbH_ext PF11724.8 KFM58085.1 - 0.088 13.1 0.1 0.098 13.0 0.1 1.1 1 0 0 1 1 1 0 YvbH-like oligomerisation region DUF3535 PF12054.8 KFM58086.1 - 2e-19 70.2 0.4 2e-19 70.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) DUF4817 PF16087.5 KFM58086.1 - 0.039 13.8 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) SNF2_N PF00176.23 KFM58087.1 - 2e-64 217.5 0.0 5.4e-64 216.1 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM58087.1 - 4.7e-15 55.9 0.0 2e-14 53.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KFM58087.1 - 7.3e-07 28.9 0.6 0.095 13.0 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat DUF3535 PF12054.8 KFM58087.1 - 2.2e-06 27.2 0.0 8.3e-05 22.0 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) ResIII PF04851.15 KFM58087.1 - 5.9e-05 23.1 0.0 0.00022 21.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HEAT_EZ PF13513.6 KFM58087.1 - 0.0021 18.5 0.5 0.25 11.9 0.0 3.3 3 0 0 3 3 3 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFM58087.1 - 0.0022 18.5 0.3 0.06 13.9 0.0 2.6 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFM58087.1 - 0.0025 17.9 0.6 3.9 7.5 0.1 2.9 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFM58087.1 - 0.026 13.1 0.2 0.055 12.0 0.2 1.5 1 0 0 1 1 1 0 Adaptin N terminal region DUF3385 PF11865.8 KFM58087.1 - 0.074 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Claudin_2 PF13903.6 KFM58089.1 - 0.0076 16.0 7.8 0.1 12.3 6.2 2.4 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF3487 PF11990.8 KFM58089.1 - 0.027 14.3 0.4 0.027 14.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Tetraspanin PF00335.20 KFM58089.1 - 0.19 11.4 3.1 0.3 10.8 0.9 2.0 2 0 0 2 2 2 0 Tetraspanin family DUF2207 PF09972.9 KFM58089.1 - 0.49 9.1 1.2 0.75 8.5 0.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MerC PF03203.14 KFM58089.1 - 6.2 7.3 10.1 0.26 11.8 2.2 2.3 3 0 0 3 3 3 0 MerC mercury resistance protein Mito_carr PF00153.27 KFM58090.1 - 1.5e-65 217.2 0.3 5e-22 77.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM58090.1 - 0.11 11.6 0.1 0.34 10.0 0.0 1.9 2 1 0 2 2 2 0 Gammaproteobacterial serine protease WD40 PF00400.32 KFM58091.1 - 3.9e-42 141.4 26.2 4.9e-06 27.2 0.2 9.3 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM58091.1 - 7.8e-12 45.3 5.3 0.023 15.0 0.1 7.2 3 3 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFM58091.1 - 0.00024 20.0 2.7 0.32 9.7 0.1 4.1 2 2 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KFM58091.1 - 0.00043 19.1 4.8 3 6.4 0.0 5.5 5 1 2 7 7 7 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KFM58091.1 - 0.00076 18.9 2.8 0.066 12.5 0.0 4.1 4 1 1 5 5 5 1 WD40-like domain Mcl1_mid PF12341.8 KFM58091.1 - 0.013 14.8 0.4 0.94 8.8 0.0 3.1 3 1 0 3 3 3 0 Minichromosome loss protein, Mcl1, middle region DUF659 PF04937.15 KFM58092.1 - 0.00021 21.2 0.2 0.00068 19.5 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM58092.1 - 0.00033 20.4 0.3 0.0013 18.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Endostatin PF06482.11 KFM58092.1 - 0.55 9.6 4.0 0.52 9.7 2.4 1.7 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin PID PF00640.23 KFM58093.1 - 7.2e-07 29.3 0.0 7.2e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFM58093.1 - 0.02 15.1 0.0 0.022 14.9 0.0 1.0 1 0 0 1 1 1 0 Phosphotyrosine-binding domain ICAP-1_inte_bdg PF10480.9 KFM58093.1 - 0.042 13.8 0.0 0.046 13.7 0.0 1.0 1 0 0 1 1 1 0 Beta-1 integrin binding protein NtA PF03146.15 KFM58095.1 - 2e-27 95.2 0.4 2.5e-27 94.9 0.4 1.1 1 0 0 1 1 1 1 Agrin NtA domain DUF4959 PF16323.5 KFM58095.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4959) Laminin_G_2 PF02210.24 KFM58096.1 - 5.8e-51 172.3 0.1 8.8e-29 100.6 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 KFM58096.1 - 1.9e-44 151.1 0.0 1.5e-25 89.9 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain EGF PF00008.27 KFM58096.1 - 1.6e-06 28.3 5.9 3.5e-06 27.2 5.9 1.6 1 0 0 1 1 1 1 EGF-like domain Laminin_G_3 PF13385.6 KFM58096.1 - 0.00049 20.3 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 KFM58096.1 - 0.0066 17.0 3.2 0.025 15.2 3.2 2.1 1 0 0 1 1 1 1 Human growth factor-like EGF HGTP_anticodon PF03129.20 KFM58099.1 - 2.5e-22 78.8 0.0 3e-21 75.4 0.0 2.4 2 1 0 2 2 2 1 Anticodon binding domain Tom37 PF10568.9 KFM58101.1 - 1.4e-34 119.1 1.9 1.7e-34 118.8 0.7 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KFM58101.1 - 4.7e-26 90.4 0.6 4e-25 87.4 0.2 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFM58101.1 - 2.7e-18 66.6 0.2 7.2e-18 65.2 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KFM58101.1 - 0.00011 22.2 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF687 PF05095.12 KFM58101.1 - 0.13 10.8 0.0 0.78 8.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF687) Glyco_hydro_18 PF00704.28 KFM58102.1 - 7.1e-25 88.4 0.1 1.1e-24 87.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 KFM58102.1 - 1.2e-20 73.3 18.5 4.4e-13 49.2 6.2 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Alpha-mann_mid PF09261.11 KFM58102.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Alpha mannosidase middle domain FlgI PF02119.16 KFM58102.1 - 0.1 11.5 0.2 0.18 10.7 0.2 1.2 1 0 0 1 1 1 0 Flagellar P-ring protein Sec7_N PF12783.7 KFM58103.1 - 0.0028 17.6 0.8 0.0067 16.3 0.0 1.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.20 KFM58104.1 - 3.4e-56 189.8 0.5 5e-56 189.3 0.5 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFM58104.1 - 1.2e-07 31.8 3.0 4.8e-07 29.8 0.1 2.6 2 1 1 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KFM58105.1 - 0.0036 15.5 0.5 0.0057 14.9 0.1 1.5 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 KFM58105.1 - 0.017 14.9 0.6 5.2 7.0 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) CBM_48 PF02922.18 KFM58106.1 - 9.4e-15 54.7 0.0 2.2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KFM58106.1 - 3.3e-10 40.1 0.2 6.4e-10 39.1 0.1 1.5 1 1 1 2 2 2 1 Alpha amylase, catalytic domain Cellulase PF00150.18 KFM58106.1 - 0.02 14.3 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Tnp_P_element PF12017.8 KFM58107.1 - 1.1e-06 28.3 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Transposase protein THAP PF05485.12 KFM58108.1 - 5e-17 62.6 0.6 9.7e-17 61.7 0.1 1.7 2 0 0 2 2 2 1 THAP domain Myb_DNA-bind_4 PF13837.6 KFM58110.1 - 9.8e-14 51.5 3.2 9.8e-14 51.5 3.2 1.8 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM58110.1 - 0.00022 21.5 2.2 0.00022 21.5 2.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 KFM58110.1 - 0.0018 18.3 0.3 0.0047 17.0 0.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFM58111.1 - 1.4e-17 63.9 2.0 2e-17 63.4 2.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM58111.1 - 7.3e-06 26.2 0.8 1.3e-05 25.4 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like HEAT_EZ PF13513.6 KFM58112.1 - 6.3e-27 93.6 4.4 5.7e-14 52.3 0.0 9.0 8 2 2 10 10 10 4 HEAT-like repeat HEAT PF02985.22 KFM58112.1 - 4.3e-24 82.5 4.7 0.0035 17.5 0.0 8.8 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 KFM58112.1 - 1.1e-19 70.6 0.2 0.00031 21.0 0.0 6.0 4 1 2 6 6 6 4 HEAT repeats IBN_N PF03810.19 KFM58112.1 - 2.9e-18 65.6 0.0 7.5e-18 64.2 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cnd1 PF12717.7 KFM58112.1 - 2.6e-12 47.1 0.2 0.0041 17.2 0.2 3.7 3 1 1 4 4 3 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KFM58112.1 - 9.9e-12 44.5 0.4 0.0033 17.4 0.0 6.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 KFM58112.1 - 4.1e-11 43.3 0.0 0.0069 17.0 0.0 4.7 2 2 2 4 4 4 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFM58112.1 - 2.9e-08 32.7 2.1 0.012 14.3 0.3 4.0 2 2 1 3 3 3 3 Adaptin N terminal region MMS19_C PF12460.8 KFM58112.1 - 7e-05 22.1 6.0 0.65 9.1 0.0 4.9 3 2 2 5 5 5 2 RNAPII transcription regulator C-terminal TAFH PF07531.14 KFM58112.1 - 0.00067 19.7 0.5 0.28 11.3 0.0 3.7 4 0 0 4 4 4 1 NHR1 homology to TAF UNC45-central PF11701.8 KFM58112.1 - 0.00071 19.6 0.2 0.11 12.4 0.0 3.1 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KFM58112.1 - 0.00086 18.9 0.0 0.048 13.2 0.0 3.2 4 0 0 4 4 4 1 CLASP N terminal Dopey_N PF04118.14 KFM58112.1 - 0.0046 16.1 0.1 0.015 14.4 0.0 1.9 2 1 0 2 2 2 1 Dopey, N-terminal RTP1_C1 PF10363.9 KFM58112.1 - 0.016 15.4 0.2 0.6 10.3 0.0 3.4 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DEK_C PF08766.11 KFM58112.1 - 0.2 11.6 0.7 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 DEK C terminal domain HEAT PF02985.22 KFM58113.1 - 7.8e-07 28.8 0.7 0.00029 20.8 0.0 3.4 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.23 KFM58113.1 - 2.6e-05 24.1 0.1 0.02 14.9 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFM58113.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFM58113.1 - 0.0014 19.1 0.0 0.23 12.0 0.0 3.1 1 1 3 4 4 4 2 HEAT-like repeat DUF3689 PF12463.8 KFM58113.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) CLASP_N PF12348.8 KFM58113.1 - 0.067 12.7 0.0 0.85 9.1 0.0 2.2 1 1 1 2 2 2 0 CLASP N terminal Adaptin_N PF01602.20 KFM58113.1 - 0.18 10.3 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region DDE_3 PF13358.6 KFM58114.1 - 3.9e-16 59.1 0.1 6.5e-15 55.2 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58114.1 - 7.5e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM58114.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM58114.1 - 0.0025 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM58114.1 - 0.016 15.3 0.1 0.065 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM58114.1 - 0.035 14.1 0.4 0.035 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix tRNA-synt_2 PF00152.20 KFM58116.1 - 1.1e-97 327.0 0.0 1.3e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Maff2 PF12750.7 KFM58116.1 - 0.024 14.5 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Maff2 family Mito_fiss_reg PF05308.11 KFM58116.1 - 0.28 11.3 0.0 0.42 10.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator HTH_Tnp_Tc3_2 PF01498.18 KFM58118.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58118.1 - 7.6e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM58119.1 - 3.2e-62 204.3 56.4 1.2e-08 35.0 0.1 9.4 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58119.1 - 9.7e-43 142.3 83.7 7.5e-06 26.1 2.8 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58119.1 - 1.9e-24 84.2 72.9 0.00035 21.2 2.3 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM58119.1 - 4.7e-17 61.8 47.1 0.029 14.7 2.4 9.8 8 1 2 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM58119.1 - 3.7e-15 55.7 67.6 0.015 15.7 2.0 9.5 10 0 0 10 10 9 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM58119.1 - 4.2e-15 55.3 54.4 0.0033 17.4 1.7 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf_ZIC PF18366.1 KFM58119.1 - 3.6e-05 23.8 47.8 0.57 10.3 0.6 8.2 1 1 7 8 8 8 4 Zic proteins zinc finger domain DUF2256 PF10013.9 KFM58119.1 - 0.0018 18.3 28.6 2 8.6 0.0 8.4 9 0 0 9 9 9 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-CHCC PF10276.9 KFM58119.1 - 0.004 17.2 16.8 17 5.5 0.1 8.0 9 0 0 9 9 9 0 Zinc-finger domain zf-RRPl_C4 PF17026.5 KFM58119.1 - 0.012 15.7 29.3 0.032 14.3 4.7 4.2 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_9 PF14369.6 KFM58119.1 - 0.013 15.8 17.4 6.9 7.0 0.1 6.8 7 0 0 7 7 7 0 zinc-ribbon C1_1 PF00130.22 KFM58119.1 - 0.046 13.6 46.5 2.6 8.0 0.3 8.3 3 2 5 8 8 8 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KFM58119.1 - 0.087 12.8 32.4 2.7 8.0 3.7 5.9 2 1 3 5 5 5 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM58119.1 - 0.15 12.8 31.2 2 9.2 1.0 4.7 1 1 3 4 4 4 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM58119.1 - 0.65 10.2 24.4 0.67 10.1 1.0 5.4 5 1 0 5 5 5 0 Zinc ribbon domain FYVE PF01363.21 KFM58119.1 - 1.5 9.0 48.1 18 5.6 8.8 5.3 1 1 3 4 4 3 0 FYVE zinc finger DZR PF12773.7 KFM58119.1 - 2.5 8.2 31.8 86 3.3 4.5 5.4 1 1 1 2 2 1 0 Double zinc ribbon zf-C2HC_2 PF13913.6 KFM58119.1 - 2.6 8.1 25.3 21 5.1 0.4 7.1 8 0 0 8 8 7 0 zinc-finger of a C2HC-type C5HCH PF17982.1 KFM58119.1 - 6.6 7.0 39.7 11 6.3 0.3 8.6 8 1 2 10 10 9 0 NSD Cys-His rich domain zf-H2C2_2 PF13465.6 KFM58120.1 - 1.5e-24 85.3 13.0 1.3e-07 31.7 0.4 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58120.1 - 1.6e-16 59.8 16.1 3.2e-06 27.3 1.7 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58120.1 - 1e-11 44.6 16.8 0.00021 21.9 0.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM58120.1 - 7.1e-10 38.9 13.8 0.00099 19.3 1.7 3.3 2 1 1 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM58120.1 - 7.4e-07 29.0 12.4 0.029 14.4 1.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM58120.1 - 2.6e-06 27.7 12.0 0.043 14.2 1.2 3.0 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.6 KFM58120.1 - 7.2e-06 25.8 5.3 0.0011 18.8 1.7 2.9 2 1 0 2 2 2 1 HNH endonuclease zf-H2C2_5 PF13909.6 KFM58120.1 - 2.5e-05 23.9 8.9 0.089 12.6 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-LYAR PF08790.11 KFM58120.1 - 3.2e-05 23.7 8.6 0.12 12.2 0.1 3.4 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf-met PF12874.7 KFM58120.1 - 3.8e-05 23.9 14.1 0.054 13.9 0.7 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type Prok-RING_1 PF14446.6 KFM58120.1 - 0.00044 20.1 3.6 4.4 7.3 0.1 3.1 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 zf-C2H2_11 PF16622.5 KFM58120.1 - 0.0021 17.8 0.5 0.0021 17.8 0.5 2.9 3 0 0 3 3 3 1 zinc-finger C2H2-type DUF2256 PF10013.9 KFM58120.1 - 0.0032 17.5 4.4 5.2 7.3 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.18 KFM58120.1 - 0.0033 17.7 0.6 2.5 8.4 0.2 2.8 1 1 2 3 3 3 1 BolA-like protein zf_C2H2_ZHX PF18387.1 KFM58120.1 - 0.0043 16.7 10.9 0.079 12.6 0.7 3.1 1 1 2 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-FCS PF06467.14 KFM58120.1 - 0.0066 16.4 6.3 3 7.9 0.5 3.1 2 1 1 3 3 3 2 MYM-type Zinc finger with FCS sequence motif zf-C2HC_2 PF13913.6 KFM58120.1 - 0.0093 15.9 4.8 0.9 9.5 0.2 3.4 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-FLZ PF04570.14 KFM58120.1 - 0.0096 15.4 4.8 5.7 6.5 0.4 3.2 2 1 1 3 3 3 0 zinc-finger of the FCS-type, C2-C2 DUF2180 PF09947.9 KFM58120.1 - 0.019 14.9 1.4 1.5 8.8 1.2 2.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_3rep PF18868.1 KFM58120.1 - 0.019 15.6 7.3 0.9 10.2 2.7 2.6 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats GAGA PF09237.11 KFM58120.1 - 0.031 14.1 0.5 5.3 6.9 0.1 2.7 1 1 2 3 3 3 0 GAGA factor DUF1744 PF08490.12 KFM58120.1 - 0.034 12.7 0.1 0.038 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Zn-C2H2_12 PF18112.1 KFM58120.1 - 0.073 13.5 10.1 0.46 11.0 1.0 3.4 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain PHF5 PF03660.14 KFM58120.1 - 0.082 13.1 3.0 0.22 11.7 3.0 1.7 1 1 0 1 1 1 0 PHF5-like protein FYDLN_acid PF09538.10 KFM58120.1 - 0.095 13.4 3.3 34 5.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-MYST PF17772.1 KFM58120.1 - 0.11 12.1 6.6 2.6 7.7 0.1 2.8 2 1 1 3 3 3 0 MYST family zinc finger domain zf_UBZ PF18439.1 KFM58120.1 - 0.14 11.8 5.6 5.9 6.6 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 KFM58120.1 - 0.16 12.2 8.5 0.83 9.9 3.2 2.2 1 1 0 2 2 2 0 TFIIH C1-like domain zf-BED PF02892.15 KFM58120.1 - 0.19 11.8 12.7 1.7 8.7 0.4 3.1 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_9 PF16293.5 KFM58120.1 - 0.2 11.5 7.6 8.1 6.4 0.3 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) NADH-G_4Fe-4S_3 PF10588.9 KFM58120.1 - 0.29 10.7 4.6 9 5.9 0.1 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C2HE PF16278.5 KFM58120.1 - 0.41 11.1 11.3 3.1 8.3 0.2 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 KFM58120.1 - 0.43 10.7 5.6 38 4.4 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal zf_ZIC PF18366.1 KFM58120.1 - 0.56 10.4 8.4 0.56 10.4 0.4 3.0 1 1 2 3 3 3 0 Zic proteins zinc finger domain LIM PF00412.22 KFM58120.1 - 0.85 9.9 9.9 14 6.0 4.5 3.0 1 1 0 2 2 2 0 LIM domain zinc_ribbon_10 PF10058.9 KFM58120.1 - 1.7 8.5 6.4 0.78 9.5 2.0 2.2 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HNH PF01844.23 KFM58120.1 - 1.9 8.8 7.6 32 4.8 0.1 3.1 3 0 0 3 3 3 0 HNH endonuclease FYVE PF01363.21 KFM58120.1 - 2 8.6 8.4 5.8 7.1 8.1 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-AN1 PF01428.16 KFM58120.1 - 2.9 8.1 11.2 7.6 6.8 3.7 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger TPR_1 PF00515.28 KFM58121.1 - 1.4e-38 129.2 9.3 8.2e-09 34.9 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFM58121.1 - 3.4e-35 117.3 3.6 1.6e-05 24.7 0.0 9.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KFM58121.1 - 2.8e-31 106.9 0.2 4.5e-08 32.6 0.0 7.9 8 1 0 8 8 8 4 TPR repeat TPR_8 PF13181.6 KFM58121.1 - 3.2e-27 92.4 6.4 0.00012 22.0 0.0 9.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFM58121.1 - 2.6e-20 72.5 3.8 4.7e-05 23.6 0.0 6.5 3 3 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFM58121.1 - 7.2e-19 66.8 9.5 0.0025 18.1 0.1 9.1 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFM58121.1 - 9.7e-19 66.5 0.0 0.024 15.4 0.0 8.4 6 3 2 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM58121.1 - 6.4e-16 58.3 0.0 0.018 15.2 0.0 6.8 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KFM58121.1 - 1.5e-14 54.3 0.1 0.18 12.5 0.0 6.9 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM58121.1 - 1.1e-11 45.0 12.3 0.00013 22.4 0.0 6.5 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM58121.1 - 9.9e-11 40.9 0.1 0.019 15.0 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat NARP1 PF12569.8 KFM58121.1 - 4.1e-08 32.6 0.9 0.019 13.9 0.0 4.9 3 2 2 5 5 5 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KFM58121.1 - 1e-06 29.0 10.3 4.5 8.1 0.2 8.2 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM58121.1 - 9.4e-06 25.3 0.5 9.7 6.2 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM58121.1 - 2.5e-05 24.4 7.2 0.0087 16.3 0.0 4.9 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KFM58121.1 - 5.8e-05 22.9 0.1 0.22 11.2 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 KFM58121.1 - 0.00036 19.8 0.4 3.5 6.8 0.0 4.6 2 2 1 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 KFM58121.1 - 0.0014 18.7 0.5 0.64 10.1 0.3 3.9 3 1 0 3 3 3 1 Domain of Unknown Function (DUF3856) MAS20 PF02064.15 KFM58121.1 - 0.01 15.9 1.5 0.19 11.8 0.1 3.3 4 0 0 4 4 3 0 MAS20 protein import receptor MIT PF04212.18 KFM58121.1 - 0.011 15.8 11.2 1.7 8.8 0.1 5.4 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 KFM58121.1 - 0.044 14.5 0.0 75 4.2 0.0 4.6 4 0 0 4 4 3 0 Sel1 repeat SHNi-TPR PF10516.9 KFM58121.1 - 0.049 13.1 1.2 9.7 5.8 0.0 3.9 4 0 0 4 4 4 0 SHNi-TPR NRBF2_MIT PF17169.4 KFM58121.1 - 0.052 13.8 0.4 6 7.2 0.0 3.1 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 RPN7 PF10602.9 KFM58121.1 - 0.2 11.3 10.3 0.55 9.9 0.0 4.0 3 2 1 4 4 4 0 26S proteasome subunit RPN7 PPR PF01535.20 KFM58121.1 - 0.41 11.0 6.3 36 4.9 0.3 4.6 5 0 0 5 5 4 0 PPR repeat 7TM_GPCR_Srw PF10324.9 KFM58123.1 - 1.3e-25 90.4 17.8 1.6e-25 90.0 17.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KFM58123.1 - 5.2e-22 78.4 20.8 6.6e-22 78.1 20.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM58123.1 - 0.00054 19.4 18.7 0.001 18.5 5.8 3.0 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Ribosomal_S19 PF00203.21 KFM58124.1 - 7.3e-37 125.1 0.6 1.1e-36 124.6 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 C2 PF00168.30 KFM58125.1 - 2.5e-25 88.7 0.1 5.2e-18 65.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KFM58125.1 - 0.00033 20.6 0.1 0.0053 16.7 0.1 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 KFM58125.1 - 0.00045 19.8 0.0 0.85 9.2 0.0 2.4 2 0 0 2 2 2 2 CEP76 C2 domain DUF5527 PF17665.1 KFM58125.1 - 0.071 12.6 0.8 0.13 11.8 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5527) He_PIG_assoc PF10632.9 KFM58125.1 - 0.12 12.1 0.2 0.64 9.7 0.1 2.2 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Prot_ATP_OB_N PF17758.1 KFM58125.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain GSH-S_N PF02951.14 KFM58126.1 - 0.034 14.3 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain F5_F8_type_C PF00754.25 KFM58127.1 - 2e-07 31.2 0.0 2.6e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain Muskelin_N PF06588.11 KFM58127.1 - 0.0059 16.5 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus XRCC1_N PF01834.16 KFM58127.1 - 0.035 14.1 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 XRCC1 N terminal domain Chitin_bind_4 PF00379.23 KFM58130.1 - 2.2e-08 34.5 3.0 2.2e-08 34.5 3.0 2.6 3 0 0 3 3 3 1 Insect cuticle protein PAP1 PF08601.10 KFM58130.1 - 4.6 6.9 15.4 5.7 6.6 15.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 TFIIA PF03153.13 KFM58130.1 - 9.5 6.1 13.9 11 5.8 13.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PDZ PF00595.24 KFM58131.1 - 3.6e-07 30.4 0.2 1.3e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFM58131.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain TMEM52 PF14979.6 KFM58131.1 - 3 7.7 6.9 0.8 9.6 2.7 2.3 2 0 0 2 2 2 0 Transmembrane 52 EF-hand_1 PF00036.32 KFM58132.1 - 8.4e-23 78.2 10.3 1.9e-07 30.1 0.3 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFM58132.1 - 7.6e-21 74.4 1.8 4.2e-14 52.8 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM58132.1 - 2.2e-17 61.4 5.8 2.6e-06 26.9 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFM58132.1 - 1.5e-15 55.8 6.4 0.0002 20.7 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFM58132.1 - 2.1e-14 53.1 6.6 0.00079 19.2 0.2 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KFM58132.1 - 2e-07 30.9 4.3 0.0004 20.3 1.0 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFM58132.1 - 2.3e-05 24.7 0.2 0.00021 21.6 0.3 2.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFM58132.1 - 0.0007 19.9 0.2 0.094 13.1 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain Caleosin PF05042.13 KFM58132.1 - 0.00073 19.5 2.6 4 7.3 0.0 3.0 2 1 0 3 3 3 2 Caleosin related protein DUF1398 PF07166.11 KFM58132.1 - 0.0064 16.5 0.3 0.022 14.8 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1398) Dockerin_1 PF00404.18 KFM58132.1 - 0.026 14.7 0.4 7.1 6.9 0.0 3.0 3 0 0 3 3 3 0 Dockerin type I domain Cpn60_TCP1 PF00118.24 KFM58133.1 - 5.9e-160 533.1 1.4 7e-160 532.9 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family STAT_bind PF02864.15 KFM58134.1 - 2.1e-48 164.2 0.2 2.1e-48 164.2 0.2 2.1 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.20 KFM58134.1 - 5.4e-47 159.9 21.0 5.4e-47 159.9 21.0 1.6 2 0 0 2 2 2 1 STAT protein, all-alpha domain STAT_int PF02865.17 KFM58134.1 - 1e-37 129.3 0.9 1e-37 129.3 0.9 3.0 2 1 1 3 3 3 1 STAT protein, protein interaction domain SH2 PF00017.24 KFM58134.1 - 4.2e-10 39.6 0.0 1.4e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 SH2 domain VWA_2 PF13519.6 KFM58134.1 - 0.48 11.1 1.9 0.85 10.3 0.7 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain SBF PF01758.16 KFM58135.1 - 2e-14 53.7 6.6 2e-14 53.7 6.6 2.0 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 KFM58135.1 - 4.2e-06 26.3 8.1 5.1e-06 26.0 8.1 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) AMMECR1 PF01871.17 KFM58136.1 - 3e-50 170.1 0.0 3.6e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 HTH_Tnp_Tc3_2 PF01498.18 KFM58138.1 - 6.3e-16 58.4 2.2 6.3e-16 58.4 2.2 2.0 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM58138.1 - 1.4e-13 50.8 0.0 2.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58138.1 - 2.9e-07 30.1 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58138.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58138.1 - 2.6 8.7 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain TPR_2 PF07719.17 KFM58139.1 - 7.7e-33 109.9 2.2 1.4e-07 31.1 0.0 7.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFM58139.1 - 4.5e-30 102.2 4.3 1.6e-08 34.0 0.1 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFM58139.1 - 1.2e-25 87.5 6.8 1.2e-05 25.1 0.0 7.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFM58139.1 - 1.5e-18 66.1 0.2 3.4e-06 26.6 0.0 6.0 3 2 3 6 6 6 4 TPR repeat TPR_12 PF13424.6 KFM58139.1 - 1.9e-18 66.5 8.8 4.2e-06 27.0 0.1 5.9 3 3 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM58139.1 - 5.5e-17 62.0 1.1 1.7e-06 28.4 0.1 5.2 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM58139.1 - 1.1e-16 59.5 3.4 3.8e-05 23.4 0.1 7.4 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM58139.1 - 2.4e-15 56.9 0.0 0.0056 17.3 0.0 5.3 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFM58139.1 - 3.9e-13 49.4 0.0 0.00086 19.4 0.1 4.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM58139.1 - 8.3e-12 44.9 2.0 0.3 12.0 0.0 6.4 4 1 3 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM58139.1 - 1.2e-11 44.7 12.2 0.00028 21.1 1.4 4.9 2 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFM58139.1 - 1.4e-10 41.1 5.4 0.18 12.5 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM58139.1 - 2e-08 34.0 2.3 0.0026 18.0 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFM58139.1 - 1.8e-06 28.2 0.0 0.00057 20.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM58139.1 - 2.5e-06 27.1 7.5 0.0055 16.5 0.1 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM58139.1 - 6.2e-06 25.6 0.0 0.097 11.9 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KFM58139.1 - 0.00088 18.1 0.1 0.011 14.6 0.0 2.4 2 1 1 3 3 3 1 Protein kinase G tetratricopeptide repeat MIT PF04212.18 KFM58139.1 - 0.0024 17.9 2.2 0.55 10.4 0.0 5.1 7 0 0 7 7 6 1 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 KFM58139.1 - 0.0035 17.4 0.5 0.04 14.0 0.0 2.9 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.6 KFM58139.1 - 0.006 16.0 0.2 0.05 13.0 0.2 2.2 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP Coatomer_E PF04733.14 KFM58139.1 - 0.0079 15.6 1.8 1.8 7.9 0.1 3.6 2 1 2 4 4 4 1 Coatomer epsilon subunit DUF4810 PF16068.5 KFM58139.1 - 0.018 15.5 0.3 1.4 9.5 0.1 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4810) ChAPs PF09295.10 KFM58139.1 - 0.02 13.9 0.6 0.067 12.2 0.1 2.0 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) NSF PF02071.20 KFM58139.1 - 0.047 14.4 1.8 69 4.9 0.1 4.8 5 0 0 5 5 2 0 Aromatic-di-Alanine (AdAR) repeat Wzy_C_2 PF11846.8 KFM58139.1 - 0.058 13.3 0.1 2 8.3 0.0 2.4 1 1 2 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal BTAD PF03704.17 KFM58139.1 - 0.065 13.7 0.6 14 6.1 0.1 2.7 1 1 2 3 3 3 0 Bacterial transcriptional activator domain DUF627 PF04781.12 KFM58139.1 - 0.18 11.8 4.5 1.1 9.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF627) DUF3808 PF10300.9 KFM58139.1 - 0.34 9.6 5.5 0.22 10.2 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3808) PDZ_5 PF17817.1 KFM58141.1 - 4.3e-05 23.7 0.0 9.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 KFM58142.1 - 1.1e-10 41.5 5.2 1.1e-10 41.4 0.1 2.8 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM58142.1 - 2.5e-10 40.6 0.2 2.5e-10 40.6 0.2 1.8 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) Cast PF10174.9 KFM58142.1 - 0.0087 14.4 16.1 0.013 13.8 16.1 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone YscO PF07321.12 KFM58142.1 - 0.029 14.3 16.5 0.027 14.4 15.1 1.7 1 1 1 2 2 2 0 Type III secretion protein YscO MCPsignal PF00015.21 KFM58142.1 - 0.14 11.9 1.8 0.31 10.8 1.8 1.6 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ADIP PF11559.8 KFM58142.1 - 0.37 10.9 20.0 1 9.5 20.0 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF745 PF05335.13 KFM58142.1 - 0.58 9.9 16.1 0.49 10.1 14.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) HAUS-augmin3 PF14932.6 KFM58142.1 - 0.58 9.7 14.1 1.1 8.8 14.1 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Sec8_exocyst PF04048.14 KFM58142.1 - 0.59 10.0 11.0 2.2 8.2 4.8 2.6 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Spc7 PF08317.11 KFM58142.1 - 0.79 8.5 16.4 1.3 7.9 16.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KFM58142.1 - 0.86 10.1 3.9 1.1 9.8 2.0 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 KFM58142.1 - 0.93 9.3 15.4 2 8.2 15.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MPS2 PF17060.5 KFM58142.1 - 2.4 7.4 12.8 3.5 6.8 12.8 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 TMF_TATA_bd PF12325.8 KFM58142.1 - 5.4 7.3 17.9 0.55 10.5 12.7 2.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KFM58142.1 - 6 7.4 19.1 12 6.4 19.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region PH PF00169.29 KFM58144.1 - 2.3e-12 47.3 0.0 1.4e-11 44.8 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KFM58144.1 - 0.00056 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain ATG16 PF08614.11 KFM58144.1 - 0.041 14.1 1.7 0.041 14.1 1.7 3.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) PH_6 PF15406.6 KFM58144.1 - 0.059 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain BLOC1_2 PF10046.9 KFM58144.1 - 0.14 12.5 6.3 0.49 10.7 3.5 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 KFM58144.1 - 0.87 9.8 9.4 0.42 10.9 4.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 KFM58144.1 - 5.4 7.3 9.9 2.1 8.6 0.5 3.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper Mod_r PF07200.13 KFM58144.1 - 7.1 6.7 15.9 3.2 7.8 11.8 2.3 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Sugarporin_N PF11471.8 KFM58144.1 - 7.3 6.6 6.3 14 5.8 0.5 2.6 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension bZIP_1 PF00170.21 KFM58144.1 - 9 6.5 13.1 3.3 7.9 3.8 3.2 2 1 1 3 3 3 0 bZIP transcription factor DnaJ PF00226.31 KFM58147.1 - 1e-26 92.8 1.7 1.8e-26 92.0 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KFM58147.1 - 7.6e-26 91.0 0.0 1.1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFM58147.1 - 5.9e-09 36.2 14.5 5.9e-09 36.2 14.5 1.9 2 0 0 2 2 2 1 DnaJ central domain RRM_3 PF08777.11 KFM58147.1 - 0.0094 16.0 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif Anti-TRAP PF15777.5 KFM58147.1 - 5.5 7.0 13.6 8.1 6.5 5.5 3.3 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DDE_Tnp_4 PF13359.6 KFM58148.1 - 4e-32 111.1 0.0 4.8e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 KFM58148.1 - 0.0028 18.0 0.1 0.0052 17.1 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KFM58148.1 - 0.017 14.7 0.2 0.034 13.8 0.2 1.5 1 1 0 1 1 1 0 Transposase DDE domain DUF4592 PF15262.6 KFM58149.1 - 0.00025 21.7 3.1 0.00025 21.7 3.1 7.5 4 3 6 10 10 10 1 Domain of unknown function (DUF4592) PAX PF00292.18 KFM58151.1 - 0.0027 17.6 0.0 0.0034 17.3 0.0 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 KFM58151.1 - 0.009 16.6 0.1 0.016 15.8 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_3 PF01381.22 KFM58151.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix MarR_2 PF12802.7 KFM58151.1 - 0.011 15.6 0.3 0.17 11.8 0.1 2.2 1 1 1 2 2 2 0 MarR family HTH_23 PF13384.6 KFM58151.1 - 0.014 15.2 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KFM58151.1 - 0.017 15.3 0.4 0.017 15.3 0.4 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM58151.1 - 0.019 14.9 0.1 0.019 14.9 0.1 1.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM58151.1 - 0.075 12.6 0.4 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding LMF1 PF06762.14 KFM58152.1 - 2.4e-52 178.5 0.9 2.7e-52 178.4 0.9 1.0 1 0 0 1 1 1 1 Lipase maturation factor LMF1 PF06762.14 KFM58153.1 - 2.3e-23 83.1 3.0 2.3e-23 83.1 3.0 1.0 1 0 0 1 1 1 1 Lipase maturation factor LMF1 PF06762.14 KFM58154.1 - 1.1e-11 44.6 0.3 1.1e-11 44.6 0.3 1.0 1 0 0 1 1 1 1 Lipase maturation factor Per1 PF04080.13 KFM58156.1 - 1.3e-39 136.6 9.9 1.5e-39 136.3 9.9 1.1 1 0 0 1 1 1 1 Per1-like family Per1 PF04080.13 KFM58157.1 - 4.7e-26 92.1 4.9 5.2e-26 91.9 4.9 1.0 1 0 0 1 1 1 1 Per1-like family Avl9 PF09794.9 KFM58158.1 - 1.2e-46 159.1 0.0 2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KFM58158.1 - 1.7e-06 27.9 0.0 3.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis P53 PF00870.18 KFM58159.1 - 1e-55 188.5 0.1 1.3e-55 188.2 0.1 1.1 1 0 0 1 1 1 1 P53 DNA-binding domain THAP PF05485.12 KFM58160.1 - 2.4e-16 60.4 2.9 3.2e-16 60.0 2.9 1.2 1 0 0 1 1 1 1 THAP domain Elf1 PF05129.13 KFM58160.1 - 0.022 14.8 0.3 0.051 13.6 0.3 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like P53 PF00870.18 KFM58161.1 - 1.5e-28 99.9 0.1 2.4e-28 99.2 0.1 1.3 1 0 0 1 1 1 1 P53 DNA-binding domain P53 PF00870.18 KFM58162.1 - 6e-23 81.6 0.1 9.2e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 P53 DNA-binding domain TRIC PF05197.13 KFM58164.1 - 2.1e-79 265.6 5.6 2.6e-79 265.3 5.6 1.1 1 0 0 1 1 1 1 TRIC channel Eno-Rase_FAD_bd PF07055.12 KFM58165.1 - 0.11 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain RhoGAP PF00620.27 KFM58166.1 - 1.7e-44 151.4 0.0 2.7e-43 147.4 0.0 2.8 2 0 0 2 2 2 1 RhoGAP domain RhoGAP-FF1 PF16512.5 KFM58166.1 - 1.2e-31 109.2 15.2 3.2e-31 107.8 2.6 4.2 4 0 0 4 4 4 2 p190-A and -B Rho GAPs FF domain Ras PF00071.22 KFM58166.1 - 1.2e-09 38.0 2.1 0.00026 20.6 0.4 4.4 4 0 0 4 4 4 3 Ras family FF PF01846.19 KFM58166.1 - 1e-08 35.2 2.3 0.034 14.3 0.2 5.4 5 0 0 5 5 5 2 FF domain NOG1 PF06858.14 KFM58166.1 - 0.11 12.3 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) DUF913 PF06025.12 KFM58166.1 - 0.98 8.3 4.5 2 7.3 4.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CUB PF00431.20 KFM58167.1 - 1.5e-11 44.6 0.0 5.4e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 CUB domain BAALC_N PF06989.12 KFM58167.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 BAALC N-terminus RT_RNaseH_2 PF17919.1 KFM58169.1 - 7.1e-14 51.7 0.0 1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM58169.1 - 0.0062 16.8 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM58169.1 - 0.044 13.3 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PRANC PF09372.10 KFM58171.1 - 0.068 13.5 0.5 0.11 12.9 0.1 1.6 2 0 0 2 2 2 0 PRANC domain WD40 PF00400.32 KFM58172.1 - 3.8e-13 49.7 7.9 7.9e-05 23.4 0.2 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 KFM58172.1 - 0.066 11.8 0.0 6.6 5.2 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 zf-H2C2_2 PF13465.6 KFM58173.1 - 3.1e-40 134.8 65.7 1.4e-06 28.4 0.9 11.4 11 1 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58173.1 - 1.4e-31 107.2 87.6 2e-05 24.8 3.2 11.3 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58173.1 - 9.1e-31 103.9 77.2 0.00033 21.3 1.9 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM58173.1 - 2.4e-14 53.1 40.9 0.023 15.0 0.3 10.6 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM58173.1 - 5.2e-11 42.6 63.4 0.17 12.3 1.0 11.2 12 0 0 12 12 11 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM58173.1 - 1.1e-09 38.0 60.8 0.0019 18.2 0.6 11.1 11 0 0 11 11 11 4 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KFM58173.1 - 2.5e-05 24.6 27.0 0.3 11.6 0.4 8.4 8 0 0 8 8 8 3 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 KFM58173.1 - 6.3e-05 23.2 52.5 0.0022 18.3 7.5 7.1 3 3 4 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFM58173.1 - 0.0012 19.0 10.3 0.87 9.9 1.1 5.0 2 1 4 6 6 6 2 BolA-like protein Elf1 PF05129.13 KFM58173.1 - 0.0014 18.6 45.4 0.0018 18.3 1.8 6.6 1 1 5 6 6 6 4 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 KFM58173.1 - 0.0014 18.3 1.9 0.0014 18.3 1.9 9.0 10 1 1 11 11 10 2 zinc-finger C2H2-type zf-HYPF PF07503.12 KFM58173.1 - 0.075 12.8 0.3 0.075 12.8 0.3 5.3 7 1 0 7 7 4 0 HypF finger C1_1 PF00130.22 KFM58173.1 - 0.15 12.0 44.7 0.36 10.7 0.4 7.9 3 2 5 8 8 8 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KFM58173.1 - 0.5 10.4 34.5 1.9 8.6 0.5 7.7 6 4 1 7 7 7 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM58173.1 - 1.4 9.7 39.3 0.49 11.2 0.9 6.0 1 1 4 5 5 4 0 zinc-ribbon family zinc_ribbon_4 PF13717.6 KFM58173.1 - 2.9 7.9 0.0 2.9 7.9 0.0 7.8 7 3 2 9 9 8 0 zinc-ribbon domain FYVE PF01363.21 KFM58173.1 - 3.8 7.7 60.9 0.21 11.8 6.2 7.4 1 1 5 6 6 5 0 FYVE zinc finger zf_Hakai PF18408.1 KFM58173.1 - 5.1 6.9 26.9 0.26 11.0 3.9 4.8 5 0 0 5 5 5 0 C2H2 Hakai zinc finger domain Zn-ribbon_8 PF09723.10 KFM58173.1 - 6.5 7.0 39.8 2.5 8.3 1.1 7.9 3 3 7 10 10 10 0 Zinc ribbon domain Cript PF10235.9 KFM58173.1 - 9 6.9 38.5 0.093 13.3 3.8 6.7 4 3 2 6 6 6 0 Microtubule-associated protein CRIPT DZR PF12773.7 KFM58173.1 - 9.7 6.3 37.2 1.8e+04 -19.4 37.2 6.1 1 1 0 1 1 0 0 Double zinc ribbon Ribosomal_L31 PF01197.18 KFM58173.1 - 9.7 6.5 10.1 2.5 8.4 2.2 3.8 3 1 1 4 4 4 0 Ribosomal protein L31 ANAPC4_WD40 PF12894.7 KFM58175.1 - 7.8e-06 26.1 0.1 0.0038 17.5 0.2 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM58175.1 - 0.00084 20.1 2.0 0.22 12.5 0.6 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Integrase_H2C2 PF17921.1 KFM58176.1 - 2.5e-19 69.1 0.1 3.7e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM58176.1 - 2e-05 24.7 0.0 4.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 KFM58176.1 - 0.001 19.2 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HHH_7 PF14635.6 KFM58177.1 - 7e-39 132.4 0.1 1.2e-38 131.6 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KFM58177.1 - 2.1e-18 66.6 0.0 4.1e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 S1 PF00575.23 KFM58177.1 - 1.2e-13 51.1 0.1 5.2e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain HHH_9 PF17674.1 KFM58177.1 - 7.6e-07 30.0 0.3 3e-06 28.0 0.3 2.1 1 1 0 1 1 1 1 HHH domain HHH_3 PF12836.7 KFM58177.1 - 0.001 19.3 0.0 0.003 17.8 0.0 1.8 1 1 0 1 1 1 1 Helix-hairpin-helix motif DDE_3 PF13358.6 KFM58179.1 - 1.2e-10 41.4 0.0 1.4e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FIBP PF05427.11 KFM58180.1 - 5.2e-36 124.7 1.6 8.8e-19 68.0 0.1 2.0 1 1 1 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) Mad3_BUB1_I PF08311.12 KFM58180.1 - 0.0044 17.0 0.4 0.0078 16.2 0.2 1.6 1 1 0 1 1 1 1 Mad3/BUB1 homology region 1 She9_MDM33 PF05546.11 KFM58180.1 - 0.03 14.1 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family Arc_C PF18162.1 KFM58180.1 - 0.049 13.5 0.7 7.2 6.5 0.1 2.1 1 1 1 2 2 2 0 Arc C-lobe STAG PF08514.11 KFM58180.1 - 0.18 11.8 2.7 0.1 12.5 0.9 1.5 2 0 0 2 2 2 0 STAG domain Anoctamin PF04547.12 KFM58182.1 - 1.2e-29 103.5 2.6 1.3e-29 103.4 2.6 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel ABC_tran_Xtn PF12848.7 KFM58182.1 - 0.078 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 ABC transporter LRR_8 PF13855.6 KFM58186.1 - 1.3e-59 197.8 31.7 3.9e-14 52.2 2.0 7.1 5 2 2 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 KFM58186.1 - 6.6e-37 124.9 38.8 3.5e-07 30.4 0.4 8.1 6 1 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM58186.1 - 8.4e-19 67.8 3.5 2.7e-05 24.1 0.0 3.4 2 1 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM58186.1 - 1.1e-17 61.9 43.8 0.25 12.0 0.1 13.8 14 1 0 14 14 14 7 Leucine Rich Repeat LRR_6 PF13516.6 KFM58186.1 - 2.3e-14 52.1 44.6 0.38 10.9 0.4 12.9 14 0 0 14 14 14 7 Leucine Rich repeat LRR_9 PF14580.6 KFM58186.1 - 1.6e-05 24.5 12.5 0.034 13.7 0.2 4.3 1 1 4 5 5 5 4 Leucine-rich repeat LRRNT PF01462.18 KFM58186.1 - 0.00088 18.9 1.3 0.0026 17.4 1.3 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Homeobox_KN PF05920.11 KFM58187.1 - 7.6e-16 57.7 0.4 1.8e-15 56.6 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFM58187.1 - 2e-07 30.7 1.1 3.7e-07 29.9 1.1 1.4 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 KFM58187.1 - 0.17 12.5 1.2 0.82 10.3 0.8 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 RPN2_C PF18004.1 KFM58187.1 - 0.31 10.9 2.1 0.67 9.9 2.1 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 KFM58187.1 - 1.1 7.3 3.3 1.4 6.9 3.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TPD PF14811.6 KFM58189.1 - 9.8e-53 177.7 0.0 1.3e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif p450 PF00067.22 KFM58190.1 - 4.3e-108 362.0 0.1 5.3e-108 361.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0542 PF15086.6 KFM58190.1 - 0.11 12.4 1.3 0.38 10.7 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Leu_zip PF15294.6 KFM58191.1 - 3.2e-89 299.1 35.0 3.6e-89 299.0 35.0 1.0 1 0 0 1 1 1 1 Leucine zipper ZapB PF06005.12 KFM58191.1 - 0.028 14.8 10.3 0.028 14.8 10.3 4.3 2 2 2 4 4 4 0 Cell division protein ZapB DUF4715 PF15835.5 KFM58191.1 - 0.039 14.0 11.4 0.059 13.4 2.6 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4715) SapB_1 PF05184.15 KFM58191.1 - 0.068 13.2 0.3 0.068 13.2 0.3 3.3 4 0 0 4 4 4 0 Saposin-like type B, region 1 SesA PF17107.5 KFM58191.1 - 0.77 10.0 9.7 0.73 10.0 2.6 3.1 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4407 PF14362.6 KFM58191.1 - 3.2 7.0 13.1 1.2 8.4 10.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GHMP_kinases_C PF08544.13 KFM58191.1 - 4.6 7.7 5.3 5.7 7.4 0.6 3.2 3 1 1 4 4 4 0 GHMP kinases C terminal Lactamase_B_6 PF16661.5 KFM58192.1 - 6.9e-63 211.6 0.3 1.9e-62 210.2 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KFM58192.1 - 4.5e-35 121.3 0.2 4.5e-35 121.3 0.2 3.1 2 2 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KFM58192.1 - 5e-20 71.9 0.0 1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KFM58192.1 - 6.9e-13 48.3 0.0 1.6e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KFM58192.1 - 1.9e-05 24.2 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFM58192.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily START PF01852.19 KFM58194.1 - 8.5e-10 38.4 0.2 1.7e-09 37.4 0.2 1.4 1 0 0 1 1 1 1 START domain Neugrin PF06413.11 KFM58194.1 - 0.022 14.8 0.8 0.041 13.9 0.8 1.4 1 0 0 1 1 1 0 Neugrin RET_CLD1 PF17756.1 KFM58194.1 - 0.035 14.4 1.5 5.7 7.2 0.0 3.3 3 0 0 3 3 3 0 RET Cadherin like domain 1 BTB PF00651.31 KFM58196.1 - 1.8e-24 86.1 0.6 1.2e-22 80.2 0.0 2.6 1 1 2 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFM58196.1 - 1.1e-21 76.9 0.9 5.3e-21 74.6 0.5 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 KFM58196.1 - 2.7e-19 69.6 0.1 3.1e-09 37.0 0.1 2.2 2 0 0 2 2 2 2 F5/8 type C domain PKK PF12474.8 KFM58199.1 - 1.1e-37 129.2 39.5 1.1e-37 129.2 39.5 3.0 2 1 0 3 3 3 1 Polo kinase kinase GIDA_assoc PF13932.6 KFM58199.1 - 7.3 6.7 22.3 27 4.9 22.3 1.9 1 1 0 1 1 1 0 GidA associated domain PKK PF12474.8 KFM58200.1 - 3.3e-15 56.4 10.6 5e-15 55.9 10.6 1.3 1 0 0 1 1 1 1 Polo kinase kinase Pkinase PF00069.25 KFM58201.1 - 7.4e-12 45.2 0.0 2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM58201.1 - 2.1e-09 37.1 0.0 4.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_Tnp_Tc3_2 PF01498.18 KFM58204.1 - 1.9e-16 60.1 2.2 4.1e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58204.1 - 2.6e-11 43.4 0.0 4.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58205.1 - 2.7e-16 59.5 2.2 4.9e-16 58.7 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58205.1 - 1.1e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58206.1 - 3.9e-16 59.0 4.5 5e-16 58.7 2.2 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58206.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease IU_nuc_hydro PF01156.19 KFM58207.1 - 5.2e-77 259.4 0.3 6.3e-77 259.1 0.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Tfb2 PF03849.14 KFM58207.1 - 0.095 11.7 0.0 10 5.0 0.0 2.2 2 0 0 2 2 2 0 Transcription factor Tfb2 HTH_Tnp_Tc3_2 PF01498.18 KFM58208.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58208.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58208.1 - 1.7e-07 30.9 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58208.1 - 0.0023 17.7 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58208.1 - 1.8 9.2 15.7 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain wnt PF00110.19 KFM58209.1 - 1.9e-14 54.0 0.6 2e-14 53.9 0.6 1.0 1 0 0 1 1 1 1 wnt family Clr5 PF14420.6 KFM58209.1 - 0.12 12.6 0.9 0.21 11.8 0.4 1.7 1 1 1 2 2 2 0 Clr5 domain wnt PF00110.19 KFM58210.1 - 5.7e-63 213.3 20.0 6.3e-63 213.2 20.0 1.0 1 0 0 1 1 1 1 wnt family wnt PF00110.19 KFM58211.1 - 7.6e-55 186.7 0.1 9.7e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 wnt family zf-RING_11 PF17123.5 KFM58211.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger DUF5437 PF17505.2 KFM58212.1 - 0.1 12.6 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5437) YccV-like PF08755.11 KFM58213.1 - 2.3e-21 76.1 2.2 3.1e-21 75.7 0.2 2.3 3 0 0 3 3 3 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KFM58213.1 - 7e-18 64.7 0.0 1.5e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KFM58213.1 - 1.3e-05 25.0 0.1 3.6e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM58213.1 - 2.4e-05 24.1 1.9 0.00012 21.8 1.9 2.4 1 1 0 1 1 1 1 F-box domain Copine PF07002.16 KFM58214.1 - 2e-44 151.6 0.0 2.5e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 KFM58214.1 - 5.6e-06 26.6 0.0 6.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 KFM58214.1 - 0.077 12.9 0.0 0.48 10.3 0.0 2.1 2 1 1 3 3 3 0 von Willebrand factor type A domain VWA PF00092.28 KFM58214.1 - 0.21 11.8 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Chordopox_A13L PF05961.11 KFM58215.1 - 0.036 14.3 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein ORC5_C PF14630.6 KFM58219.1 - 1.8e-56 191.8 0.0 2.2e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.6 KFM58219.1 - 1.8e-05 25.0 0.0 6.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFM58219.1 - 0.0041 17.5 0.0 0.02 15.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain HOOK PF05622.12 KFM58220.1 - 5.2e-258 857.9 77.5 6e-258 857.7 77.5 1.0 1 0 0 1 1 1 1 HOOK protein XhlA PF10779.9 KFM58220.1 - 0.0055 16.9 3.1 0.0055 16.9 3.1 8.1 7 3 1 8 8 8 4 Haemolysin XhlA CALCOCO1 PF07888.11 KFM58220.1 - 2.6 6.8 83.1 1.2 7.9 49.8 2.5 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 KFM58220.1 - 3.9 6.3 84.9 0.3 9.9 22.1 4.5 1 1 3 4 4 4 0 Spc7 kinetochore protein DDE_Tnp_1_7 PF13843.6 KFM58221.1 - 8.9e-09 35.1 0.0 9.5e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 HTH_psq PF05225.16 KFM58222.1 - 0.00013 21.7 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Tnp_zf-ribbon_2 PF13842.6 KFM58223.1 - 0.0029 18.4 12.4 0.0052 17.6 12.4 1.5 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon IBR PF01485.21 KFM58223.1 - 0.0038 17.4 3.5 0.0047 17.1 3.5 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain Eapp_C PF10238.9 KFM58223.1 - 0.0095 16.0 1.2 0.0095 16.0 1.2 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein Gal11_ABD1 PF18535.1 KFM58223.1 - 0.092 12.8 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) zf-B_box PF00643.24 KFM58223.1 - 0.42 10.8 7.5 0.63 10.2 7.5 1.3 1 1 0 1 1 1 0 B-box zinc finger DDE_Tnp_4 PF13359.6 KFM58225.1 - 2.2e-22 79.4 0.0 3.1e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM58225.1 - 0.00036 20.2 0.0 0.00053 19.6 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein Ig_3 PF13927.6 KFM58226.1 - 3.3e-08 34.0 0.8 0.0059 17.2 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Laminin_EGF PF00053.24 KFM58226.1 - 1e-07 31.9 125.3 0.01 16.0 12.6 9.0 2 2 7 9 9 9 5 Laminin EGF domain I-set PF07679.16 KFM58226.1 - 0.00024 21.1 0.1 0.11 12.6 0.0 3.3 2 1 0 2 2 2 1 Immunoglobulin I-set domain EGF_2 PF07974.13 KFM58226.1 - 0.0085 16.4 14.1 0.0085 16.4 14.1 12.8 10 4 4 14 14 14 4 EGF-like domain hEGF PF12661.7 KFM58226.1 - 0.012 16.2 8.2 0.012 16.2 8.2 10.3 10 2 1 11 11 11 0 Human growth factor-like EGF fn3 PF00041.21 KFM58226.1 - 0.1 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type III domain HTH_Tnp_Tc3_2 PF01498.18 KFM58227.1 - 6e-15 55.2 2.7 9.8e-15 54.6 2.0 1.7 2 0 0 2 2 1 1 Transposase MarR_2 PF12802.7 KFM58227.1 - 5.6e-05 22.9 0.4 0.013 15.4 0.1 2.5 1 1 1 2 2 2 1 MarR family HTH_32 PF13565.6 KFM58227.1 - 0.00078 20.0 10.3 0.0055 17.3 3.1 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_3 PF01381.22 KFM58227.1 - 0.00091 19.2 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_24 PF13412.6 KFM58227.1 - 0.0027 17.2 0.3 0.076 12.6 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KFM58227.1 - 0.0066 16.4 0.8 0.017 15.1 0.1 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain DDE_3 PF13358.6 KFM58227.1 - 0.0094 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r4 PF04545.16 KFM58227.1 - 0.014 14.9 0.1 0.041 13.4 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_31 PF13560.6 KFM58227.1 - 0.04 14.3 3.0 0.39 11.1 0.3 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 KFM58227.1 - 0.064 13.4 1.6 0.096 12.8 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain PAX PF00292.18 KFM58227.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain HTH_23 PF13384.6 KFM58227.1 - 0.1 12.5 0.1 0.1 12.5 0.1 3.0 4 0 0 4 4 4 0 Homeodomain-like domain DUF4749 PF15936.5 KFM58228.1 - 2e-09 38.4 0.3 2e-09 38.4 0.3 3.4 2 1 2 4 4 4 1 Domain of unknown function (DUF4749) DUF463 PF04317.12 KFM58228.1 - 0.14 11.0 2.2 0.27 10.1 2.2 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 Peptidase_A17 PF05380.13 KFM58229.1 - 1.6e-12 47.7 0.1 1.9e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 Pao retrotransposon peptidase LIM PF00412.22 KFM58230.1 - 2e-15 56.8 4.6 2.2e-15 56.6 4.6 1.1 1 0 0 1 1 1 1 LIM domain YacG PF03884.14 KFM58230.1 - 0.039 13.7 4.6 0.99 9.2 0.3 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Pea-VEAacid PF08111.11 KFM58230.1 - 0.08 13.3 0.2 0.17 12.3 0.2 1.4 1 0 0 1 1 1 0 Pea-VEAacid family zf_UBZ PF18439.1 KFM58230.1 - 0.12 12.0 1.5 0.12 12.0 1.5 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 KFM58230.1 - 6.2 6.9 11.0 0.089 12.8 4.0 1.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain QVR PF17064.5 KFM58231.1 - 7.2e-06 26.2 10.6 3.8e-05 23.8 10.6 2.0 1 1 0 1 1 1 1 Sleepless protein DDE_3 PF13358.6 KFM58233.1 - 4e-08 33.1 0.0 5.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.18 KFM58233.1 - 1.4e-06 28.0 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) rve PF00665.26 KFM58233.1 - 0.031 14.4 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain ParB PF08775.10 KFM58233.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 ParB family Nuc_sug_transp PF04142.15 KFM58234.1 - 9e-11 41.5 11.3 1e-10 41.3 11.3 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFM58234.1 - 0.025 14.7 10.4 0.031 14.4 10.4 1.1 1 0 0 1 1 1 0 EamA-like transporter family DUF1979 PF09322.10 KFM58234.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) Ribosomal_S8e PF01201.22 KFM58236.1 - 7.3e-28 97.5 2.0 7.3e-28 97.5 2.0 2.2 1 1 1 2 2 2 1 Ribosomal protein S8e TPR_8 PF13181.6 KFM58237.1 - 5.9e-25 85.4 8.1 0.034 14.4 0.0 10.7 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFM58237.1 - 2.5e-24 83.4 19.3 0.044 13.9 0.0 11.3 12 0 0 12 12 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFM58237.1 - 2e-20 71.7 16.2 0.022 14.6 0.0 10.9 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFM58237.1 - 2.2e-17 62.3 19.8 0.012 16.4 0.0 10.5 7 3 4 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFM58237.1 - 9e-16 58.2 16.4 0.00097 19.6 0.0 7.6 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFM58237.1 - 4.3e-11 42.9 18.5 0.034 14.4 0.0 8.2 8 1 0 8 8 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM58237.1 - 8e-11 42.0 20.2 0.00034 20.8 0.2 6.7 7 1 1 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFM58237.1 - 1.1e-10 42.0 18.4 0.13 13.0 0.0 7.6 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM58237.1 - 1e-09 37.9 5.9 1.8 8.3 0.0 8.1 8 0 0 8 8 8 2 TPR repeat TPR_6 PF13174.6 KFM58237.1 - 3.8e-08 33.4 6.0 0.29 11.8 0.1 8.4 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM58237.1 - 7.1e-08 32.3 8.9 4.3 7.9 0.0 8.2 10 0 0 10 10 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM58237.1 - 2.4e-06 27.2 9.3 19 5.6 0.3 8.8 10 0 0 10 10 8 0 Tetratricopeptide repeat DUF3808 PF10300.9 KFM58237.1 - 0.00089 18.1 1.6 0.0015 17.3 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_21 PF09976.9 KFM58237.1 - 0.0038 17.0 9.6 1.2 8.8 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KFM58237.1 - 0.0053 16.9 8.0 30 4.9 0.0 5.3 3 2 1 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 KFM58237.1 - 0.0078 15.2 4.9 0.7 8.7 0.5 4.1 3 2 1 4 4 4 1 NMDA receptor-regulated protein 1 Tcf25 PF04910.14 KFM58237.1 - 0.014 14.5 1.8 0.66 9.0 0.1 2.4 2 0 0 2 2 2 0 Transcriptional repressor TCF25 TPR_MalT PF17874.1 KFM58237.1 - 0.049 13.0 23.6 1.4 8.3 0.1 5.2 4 2 2 6 6 6 0 MalT-like TPR region DUF4919 PF16266.5 KFM58237.1 - 0.057 13.4 0.5 1.2 9.0 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4919) Herpes_BBRF1 PF04793.12 KFM58237.1 - 0.057 12.4 0.7 2.9 6.9 0.0 2.9 3 1 1 4 4 4 0 BRRF1-like protein FAT PF02259.23 KFM58237.1 - 0.069 12.4 4.7 4.2 6.5 0.1 4.2 3 2 0 3 3 3 0 FAT domain HrpB1_HrpK PF09613.10 KFM58237.1 - 0.077 12.6 6.5 2.7 7.6 0.0 4.2 4 0 0 4 4 3 0 Bacterial type III secretion protein (HrpB1_HrpK) ImpA_N PF06812.12 KFM58237.1 - 0.08 13.1 0.3 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system TPR_4 PF07721.14 KFM58237.1 - 0.15 12.8 10.9 0.36 11.6 0.2 5.3 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFM58237.1 - 0.17 12.2 12.2 2.8 8.3 0.2 5.1 6 1 2 8 8 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM58237.1 - 0.75 9.9 10.4 1.6 8.8 0.2 6.0 8 0 0 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFM58237.1 - 2.2 8.3 26.5 0.17 11.8 0.6 7.5 10 1 1 11 11 9 0 Tetratricopeptide repeat HTH_32 PF13565.6 KFM58238.1 - 8.9e-05 23.0 0.1 0.0008 20.0 0.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_48 PF17906.1 KFM58238.1 - 0.0095 16.0 0.1 0.023 14.8 0.1 1.7 1 0 0 1 1 1 1 HTH domain in Mos1 transposase SWIRM-assoc_2 PF16496.5 KFM58241.1 - 6.3e-181 601.8 9.3 6.3e-181 601.8 9.3 2.4 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 KFM58241.1 - 2.3e-31 107.9 0.6 6.2e-31 106.6 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KFM58241.1 - 6.4e-30 102.9 15.0 1.5e-29 101.7 15.0 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM-assoc_3 PF16498.5 KFM58241.1 - 1e-28 99.4 2.2 4.4e-28 97.3 2.2 2.1 1 0 0 1 1 1 1 SWIRM-associated domain at the C-terminal Myb_DNA-binding PF00249.31 KFM58241.1 - 5.1e-12 45.8 1.3 9e-12 45.0 0.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM58241.1 - 7.7e-06 26.1 0.0 1.8e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF919 PF06034.11 KFM58241.1 - 0.88 9.5 5.7 2.2 8.2 5.7 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Clat_adaptor_s PF01217.20 KFM58242.1 - 5.4e-31 107.4 1.8 6.7e-31 107.1 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Bravo_FIGEY PF13882.6 KFM58243.1 - 2.6e-27 96.0 3.6 4.8e-27 95.2 3.6 1.4 1 0 0 1 1 1 1 Bravo-like intracellular region DUF4064 PF13273.6 KFM58243.1 - 0.034 14.4 0.1 0.077 13.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Herpes_gE PF02480.16 KFM58243.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CrgA PF06781.12 KFM58243.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Cell division protein CrgA TMEM154 PF15102.6 KFM58243.1 - 0.19 11.7 0.0 0.44 10.5 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family DUF19 PF01579.18 KFM58244.1 - 0.25 11.1 8.8 0.02 14.7 3.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF19) NAD_binding_2 PF03446.15 KFM58247.1 - 6.4e-34 117.4 0.0 1.3e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFM58247.1 - 2.1e-18 66.7 0.2 3.9e-18 65.9 0.2 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFM58247.1 - 3.9e-09 37.0 0.0 1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KFM58247.1 - 5.5e-05 23.2 0.0 8.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KFM58247.1 - 0.00022 21.2 0.3 0.00045 20.1 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM58247.1 - 0.00026 20.4 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFM58247.1 - 0.00029 20.5 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 KFM58247.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 KFM58247.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Guanylate_cyc PF00211.20 KFM58250.1 - 2.6e-27 95.6 0.0 2.8e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PG_binding_2 PF08823.11 KFM58250.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Sulfotransfer_2 PF03567.14 KFM58252.1 - 6.3e-36 124.6 1.5 1.4e-35 123.4 1.5 1.6 1 1 0 1 1 1 1 Sulfotransferase family EXOSC1 PF10447.9 KFM58253.1 - 9.3e-15 55.2 0.5 5e-11 43.2 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KFM58253.1 - 1.4e-07 31.2 0.4 3.5e-07 29.9 0.2 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region Patched PF02460.18 KFM58254.1 - 7e-84 282.4 29.7 5.7e-56 190.1 4.6 2.0 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KFM58254.1 - 9.1e-56 187.9 9.1 9.1e-56 187.9 9.1 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KFM58254.1 - 0.00011 21.2 5.2 0.00011 21.2 5.2 2.4 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.19 KFM58254.1 - 0.68 7.5 12.9 0.018 12.7 6.0 1.7 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Sid-5 PF17204.3 KFM58254.1 - 5.4 7.3 6.0 22 5.3 0.0 3.9 3 0 0 3 3 3 0 Sid-5 family PNP_phzG_C PF10590.9 KFM58255.1 - 0.04 14.0 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Di19_C PF14571.6 KFM58255.1 - 0.39 11.3 3.9 0.41 11.2 0.9 2.1 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal Herpes_UL52 PF03121.15 KFM58256.1 - 0.018 15.0 1.2 0.02 14.8 0.2 1.7 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase WIF PF02019.18 KFM58257.1 - 1e-29 102.9 0.0 1.3e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 WIF domain EGF_2 PF07974.13 KFM58257.1 - 2.2e-16 59.9 88.8 0.00051 20.3 11.5 5.6 5 0 0 5 5 5 5 EGF-like domain EGF PF00008.27 KFM58257.1 - 1.6e-13 50.7 71.0 0.0015 18.8 10.6 6.0 5 2 0 5 5 5 5 EGF-like domain hEGF PF12661.7 KFM58257.1 - 1.1e-06 29.1 73.6 0.018 15.7 4.4 7.6 8 0 0 8 8 8 5 Human growth factor-like EGF Laminin_EGF PF00053.24 KFM58257.1 - 0.35 11.0 73.2 5.1 7.3 7.8 5.5 2 1 3 5 5 5 0 Laminin EGF domain DUF4371 PF14291.6 KFM58258.1 - 8.2e-10 38.7 0.0 2.5e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) SK_channel PF03530.14 KFM58260.1 - 6e-12 45.6 0.3 9e-12 45.0 0.3 1.3 1 0 0 1 1 1 1 Calcium-activated SK potassium channel DUF1858 PF08984.11 KFM58260.1 - 0.02 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) COesterase PF00135.28 KFM58261.1 - 8e-121 404.4 0.2 9.9e-121 404.1 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM58261.1 - 0.0024 17.8 0.8 0.011 15.6 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DNA_methylase PF00145.17 KFM58262.1 - 3.2e-49 168.1 0.0 3.8e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF4476 PF14771.6 KFM58262.1 - 0.0096 16.2 0.1 0.029 14.7 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) Lipase PF00151.19 KFM58263.1 - 1.8e-94 316.8 0.0 2.1e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFM58263.1 - 0.0001 22.9 0.3 0.0029 18.2 0.1 2.4 2 0 0 2 2 2 1 PLAT/LH2 domain Abhydrolase_6 PF12697.7 KFM58263.1 - 0.0018 19.0 0.1 0.0024 18.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM58263.1 - 0.055 13.1 0.1 0.23 11.1 0.1 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Fibrinogen_C PF00147.18 KFM58264.1 - 8.3e-71 238.3 3.5 1.5e-70 237.4 3.5 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF16 PF01519.16 KFM58264.1 - 0.00023 21.6 6.8 1.1 9.7 0.0 4.0 2 1 0 2 2 2 2 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 KFM58264.1 - 0.00075 19.9 7.4 0.18 12.2 0.1 3.8 3 1 1 4 4 4 2 Snapin/Pallidin DUF2730 PF10805.8 KFM58264.1 - 0.0031 17.6 5.0 0.77 9.9 0.0 3.9 4 1 1 5 5 5 1 Protein of unknown function (DUF2730) Serine_rich PF08824.10 KFM58264.1 - 0.13 12.2 1.0 0.39 10.7 0.9 1.9 1 1 0 1 1 1 0 Serine rich protein interaction domain BLOC1_2 PF10046.9 KFM58264.1 - 0.19 12.1 7.8 0.68 10.3 0.1 4.3 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 KFM58264.1 - 0.26 11.3 4.9 5.1 7.1 0.2 3.7 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KFM58264.1 - 0.27 11.7 8.6 39 4.8 4.4 4.4 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CorA PF01544.18 KFM58264.1 - 0.28 10.4 1.9 8 5.7 0.0 2.9 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein APG17 PF04108.12 KFM58264.1 - 0.95 8.5 4.9 0.5 9.4 1.0 2.4 2 1 0 2 2 2 0 Autophagy protein Apg17 DUF2408 PF10303.9 KFM58264.1 - 0.95 10.0 7.6 2.6 8.6 1.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Rx_N PF18052.1 KFM58264.1 - 1.1 9.5 5.5 17 5.8 1.2 4.3 5 1 0 5 5 5 0 Rx N-terminal domain DUF1664 PF07889.12 KFM58264.1 - 1.3 9.1 11.4 6.1 6.9 2.2 4.0 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KFM58264.1 - 1.5 9.0 9.0 0.14 12.4 1.2 2.8 3 1 0 3 3 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 KFM58264.1 - 2.2 7.8 5.0 7.1 6.1 1.0 2.3 1 1 0 2 2 2 0 Exonuclease VII, large subunit CLZ PF16526.5 KFM58264.1 - 2.5 8.5 10.5 15 6.1 0.1 4.5 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Allexi_40kDa PF05549.11 KFM58264.1 - 6.9 6.1 7.7 4.9 6.6 2.5 2.8 2 1 1 3 3 3 0 Allexivirus 40kDa protein Reeler PF02014.16 KFM58265.1 - 5.9e-27 95.0 0.0 6.8e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Reeler domain Acetyltransf_18 PF18014.1 KFM58265.1 - 0.087 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain KRE1 PF17056.5 KFM58265.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 Pkinase PF00069.25 KFM58266.1 - 1.8e-64 217.7 0.0 1.8e-64 217.7 0.0 2.9 3 2 1 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM58266.1 - 1.2e-45 155.8 5.7 3.2e-45 154.4 0.0 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 KFM58266.1 - 0.013 15.4 0.0 0.013 15.4 0.0 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family ORMDL PF04061.14 KFM58267.1 - 8.8e-54 181.0 10.1 9.8e-54 180.8 10.1 1.0 1 0 0 1 1 1 1 ORMDL family Pkinase PF00069.25 KFM58268.1 - 1.2e-13 51.0 0.0 1.6e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Strabismus PF06638.11 KFM58269.1 - 4.2e-227 754.8 0.0 5.1e-227 754.5 0.0 1.0 1 0 0 1 1 1 1 Strabismus protein Pre-PUA PF17832.1 KFM58270.1 - 2.5e-24 85.8 0.1 1e-23 83.8 0.1 2.2 1 0 0 1 1 1 1 Pre-PUA-like domain SUI1 PF01253.22 KFM58270.1 - 9.7e-19 67.7 0.6 9.7e-19 67.7 0.6 2.2 2 0 0 2 2 2 1 Translation initiation factor SUI1 PUA PF01472.20 KFM58270.1 - 3.6e-06 26.9 0.1 1e-05 25.4 0.1 1.8 1 0 0 1 1 1 1 PUA domain SWIB PF02201.18 KFM58270.1 - 0.0029 17.4 0.0 0.0086 15.9 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF1947 PF09183.10 KFM58270.1 - 0.015 15.6 1.5 0.11 12.8 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Kin17_mid PF10357.9 KFM58270.1 - 0.017 15.0 0.3 0.035 14.0 0.3 1.5 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein RepB-RCR_reg PF10723.9 KFM58270.1 - 0.024 14.6 0.3 0.12 12.3 0.1 2.2 2 0 0 2 2 2 0 Replication regulatory protein RepB DUF4833 PF16117.5 KFM58270.1 - 0.084 12.9 0.9 0.51 10.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4833) CUB PF00431.20 KFM58271.1 - 9.8e-09 35.5 0.1 1.5e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 CUB domain SOCS_box PF07525.16 KFM58272.1 - 6e-12 45.7 2.1 1.6e-11 44.3 2.1 1.8 1 0 0 1 1 1 1 SOCS box p450 PF00067.22 KFM58273.1 - 2e-108 363.2 0.0 2.3e-108 362.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.10 KFM58273.1 - 0.12 11.8 1.2 0.23 10.9 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kazal_2 PF07648.15 KFM58274.1 - 1.3e-29 102.0 29.9 6.2e-11 42.3 4.0 3.6 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM58274.1 - 8.6e-18 64.1 33.4 2.2e-06 27.5 5.9 3.5 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain DDE_3 PF13358.6 KFM58275.1 - 2.6e-13 50.0 0.0 4.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58275.1 - 1.4e-08 34.8 5.8 3e-08 33.8 5.8 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM58275.1 - 4.4e-05 24.0 3.7 0.00039 21.0 0.8 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM58275.1 - 0.0043 16.9 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 Tc3 transposase SpoIIID PF12116.8 KFM58275.1 - 0.02 15.0 0.9 0.039 14.1 0.9 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_38 PF13936.6 KFM58275.1 - 0.055 13.2 1.4 1.4 8.8 0.0 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain DED PF01335.21 KFM58276.1 - 0.035 14.4 0.4 0.073 13.4 0.4 1.5 1 0 0 1 1 1 0 Death effector domain BAR_3_WASP_bdg PF10456.9 KFM58276.1 - 0.052 13.0 0.1 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein PRE_C2HC PF07530.11 KFM58276.1 - 0.18 11.9 4.1 0.11 12.6 1.7 1.9 2 0 0 2 2 2 0 Associated with zinc fingers Jiv90 PF14901.6 KFM58276.1 - 0.97 9.6 6.3 1.9 8.7 6.3 1.5 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone 2OG-FeII_Oxy_2 PF13532.6 KFM58277.1 - 5.6e-15 56.0 0.0 6.6e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily fn3 PF00041.21 KFM58279.1 - 9.6e-13 48.3 0.0 6.5e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain ig PF00047.25 KFM58279.1 - 0.0025 17.9 0.3 0.0099 16.0 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM58279.1 - 0.009 16.6 0.0 0.044 14.4 0.0 2.1 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 KFM58279.1 - 0.092 13.1 2.5 0.2 12.0 0.1 2.7 2 1 0 2 2 2 0 Immunoglobulin domain V-set PF07686.17 KFM58279.1 - 0.12 12.6 1.4 0.52 10.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin V-set domain fn3 PF00041.21 KFM58280.1 - 2e-05 24.8 1.3 0.00019 21.7 0.7 2.0 2 0 0 2 2 2 1 Fibronectin type III domain DUF756 PF05506.12 KFM58280.1 - 0.072 14.0 0.3 0.9 10.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF756) fn3 PF00041.21 KFM58281.1 - 1.5e-12 47.7 0.2 1e-05 25.7 0.0 3.4 2 1 0 2 2 2 2 Fibronectin type III domain DUF2650 PF10853.8 KFM58282.1 - 0.00054 19.6 0.9 0.001 18.7 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) Holin_SPP1 PF04688.13 KFM58282.1 - 0.094 12.9 0.2 0.27 11.4 0.2 1.7 1 1 0 1 1 1 0 SPP1 phage holin P-mevalo_kinase PF04275.14 KFM58283.1 - 1.3e-46 157.2 0.1 1.7e-46 156.9 0.1 1.1 1 0 0 1 1 1 1 Phosphomevalonate kinase AAA_18 PF13238.6 KFM58283.1 - 0.054 14.0 0.0 0.08 13.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain SRTM1 PF15872.5 KFM58284.1 - 0.36 11.0 4.1 0.72 10.0 4.1 1.4 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Oxysterol_BP PF01237.18 KFM58286.1 - 2.3e-139 464.4 1.1 2.9e-139 464.1 1.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.7 KFM58288.1 - 5.7e-24 84.5 1.3 1.5e-14 54.3 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM58288.1 - 4.3e-23 81.4 5.6 1e-12 48.3 0.0 4.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM58288.1 - 3.9e-21 74.8 3.5 6.8e-09 35.8 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM58288.1 - 3.3e-19 68.4 8.8 2.1e-08 34.2 0.1 5.0 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFM58288.1 - 3.4e-19 66.9 3.4 1.6e-06 28.0 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat DUF3881 PF12997.7 KFM58288.1 - 0.11 11.7 0.1 0.63 9.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) Peptidase_C54 PF03416.19 KFM58292.1 - 2.5e-76 256.7 0.0 2.9e-76 256.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Alk_phosphatase PF00245.20 KFM58294.1 - 3e-129 431.6 0.0 3.5e-129 431.4 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KFM58294.1 - 0.0065 15.9 0.0 0.0082 15.5 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KFM58294.1 - 0.072 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 KFM58295.1 - 2e-131 438.8 0.0 2.3e-131 438.6 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KFM58295.1 - 0.0085 15.5 0.0 0.011 15.1 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KFM58295.1 - 0.024 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFM58295.1 - 0.13 11.7 0.2 1 8.7 0.2 2.4 1 1 0 1 1 1 0 Sulfatase Serpin PF00079.20 KFM58296.1 - 2.9e-114 382.2 0.4 3.3e-114 382.0 0.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Nexin_C PF08628.12 KFM58297.1 - 0.025 15.1 0.4 0.082 13.5 0.4 1.8 1 0 0 1 1 1 0 Sorting nexin C terminal DUF4652 PF15525.6 KFM58297.1 - 0.06 13.1 0.6 0.14 11.9 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) MAP17 PF15807.5 KFM58297.1 - 4.7 7.5 6.9 25 5.1 2.7 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 zf-UBR PF02207.20 KFM58298.1 - 4.9e-19 68.3 10.8 4.9e-19 68.3 10.8 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Ras PF00071.22 KFM58299.1 - 1.9e-40 138.1 0.0 2.3e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM58299.1 - 3.4e-19 69.2 0.0 4.8e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFM58299.1 - 4.2e-05 23.6 0.0 6.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFM58299.1 - 8.7e-05 22.0 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 KFM58299.1 - 0.0044 16.4 0.0 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein SRPRB PF09439.10 KFM58299.1 - 0.0089 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ProQ PF04352.13 KFM58299.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 ProQ/FINO family MtN3_slv PF03083.16 KFM58300.1 - 1.4e-48 162.8 14.9 5.2e-27 93.7 2.2 2.3 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 KFM58300.1 - 0.051 13.3 0.2 0.051 13.3 0.2 4.5 5 1 1 6 6 6 0 PQ loop repeat CRCB PF02537.15 KFM58300.1 - 0.69 10.3 10.9 1.5 9.2 9.5 2.2 1 1 1 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) BAMBI PF06211.12 KFM58303.1 - 5.9e-10 39.4 12.1 3e-08 33.9 3.2 2.4 1 1 1 2 2 2 2 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Ferric_reduct PF01794.19 KFM58303.1 - 0.076 13.1 0.8 0.43 10.7 0.1 2.0 2 0 0 2 2 2 0 Ferric reductase like transmembrane component MUG113 PF13455.6 KFM58303.1 - 0.27 11.9 1.8 0.31 11.8 0.5 1.7 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 DDE_3 PF13358.6 KFM58304.1 - 7.3e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease BAMBI PF06211.12 KFM58305.1 - 5.9e-09 36.1 4.3 1.1e-08 35.3 4.3 1.3 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Activin_recp PF01064.23 KFM58305.1 - 5.1e-05 24.3 6.6 7.5e-05 23.7 6.6 1.2 1 0 0 1 1 1 1 Activin types I and II receptor domain MFS_1 PF07690.16 KFM58306.1 - 1.8e-07 30.4 6.8 1.8e-07 30.4 6.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFM58307.1 - 1.1e-17 63.7 4.7 1.2e-17 63.6 4.7 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein ABC2_membrane_3 PF12698.7 KFM58308.1 - 8.8e-43 146.7 8.7 1.2e-42 146.3 8.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KFM58308.1 - 1.6e-38 132.3 0.0 3.3e-24 86.0 0.0 2.7 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KFM58308.1 - 3.8e-16 59.8 0.1 1.1e-05 25.4 0.0 3.7 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 KFM58308.1 - 0.00022 20.7 10.8 0.011 15.1 8.3 2.5 2 0 0 2 2 2 2 ABC-2 type transporter SbcCD_C PF13558.6 KFM58308.1 - 0.004 17.3 0.0 3.7 7.9 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF4162 PF13732.6 KFM58308.1 - 0.066 13.9 0.6 27 5.6 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4162) ABC2_membrane_3 PF12698.7 KFM58309.1 - 7.9e-25 87.7 19.6 1.2e-24 87.1 19.6 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein BPD_transp_1 PF00528.22 KFM58309.1 - 0.072 12.8 0.1 0.072 12.8 0.1 3.2 2 2 1 3 3 3 0 Binding-protein-dependent transport system inner membrane component ABC2_membrane_2 PF12679.7 KFM58309.1 - 2 7.7 11.5 5.7 6.1 11.4 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein S-methyl_trans PF02574.16 KFM58310.1 - 9.4e-23 81.4 0.0 1e-22 81.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase NCD3G PF07562.14 KFM58311.1 - 0.019 14.9 4.1 0.021 14.8 4.1 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR DUF2986 PF11661.8 KFM58312.1 - 0.034 14.7 5.6 0.095 13.2 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) IglC PF11550.8 KFM58312.1 - 0.24 10.8 0.8 0.3 10.5 0.8 1.1 1 0 0 1 1 1 0 Intracellular growth locus C protein tRNA_int_endo PF01974.17 KFM58313.1 - 8.6e-22 77.0 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PRTase_1 PF11202.8 KFM58313.1 - 0.022 14.0 0.0 0.026 13.8 0.0 1.0 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) IBR PF01485.21 KFM58316.1 - 0.0072 16.5 15.9 0.01 16.1 15.9 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DUF4637 PF15470.6 KFM58316.1 - 0.084 12.6 6.9 0.097 12.4 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) zf-RING_2 PF13639.6 KFM58316.1 - 0.2 12.0 11.0 0.31 11.4 11.0 1.3 1 0 0 1 1 1 0 Ring finger domain zf-AN1 PF01428.16 KFM58316.1 - 1.3 9.2 15.6 6.5 7.0 15.6 1.9 1 1 0 1 1 1 0 AN1-like Zinc finger zf-RING_5 PF14634.6 KFM58316.1 - 3.4 7.7 15.6 7.4 6.6 15.6 1.6 1 1 0 1 1 1 0 zinc-RING finger domain NUC173 PF08161.12 KFM58318.1 - 7.9e-69 231.4 1.5 5e-66 222.3 0.2 3.0 2 0 0 2 2 2 2 NUC173 domain MMS19_C PF12460.8 KFM58318.1 - 0.00057 19.1 4.6 0.0008 18.6 3.2 1.9 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal RPN7 PF10602.9 KFM58318.1 - 0.016 14.9 4.4 0.019 14.7 0.5 2.8 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Telomere_reg-2 PF10193.9 KFM58318.1 - 0.2 12.1 8.4 38 4.8 0.1 4.7 4 1 0 4 4 4 0 Telomere length regulation protein Vac14_Fab1_bd PF12755.7 KFM58318.1 - 1.8 9.2 5.9 8.6 7.0 0.2 4.4 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region RICTOR_M PF14666.6 KFM58318.1 - 1.9 8.3 8.1 2.5 7.9 0.1 4.2 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain HTH_29 PF13551.6 KFM58319.1 - 0.051 13.6 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Muted PF14942.6 KFM58321.1 - 1e-40 139.4 14.0 1.3e-40 139.1 14.0 1.1 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein SLATT_fungal PF18142.1 KFM58321.1 - 2.5 8.1 5.9 1.9 8.5 1.1 2.3 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Muted PF14942.6 KFM58322.1 - 1.2e-38 132.8 11.7 1.3e-38 132.6 11.7 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein DUF305 PF03713.13 KFM58322.1 - 0.0018 18.4 0.5 0.0025 18.0 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF305) Glucan_synthase PF02364.15 KFM58322.1 - 0.041 12.0 1.1 0.058 11.6 1.0 1.2 1 1 0 1 1 1 0 1,3-beta-glucan synthase component PI3K_C2 PF00792.24 KFM58322.1 - 0.081 12.8 0.1 0.14 12.1 0.1 1.6 1 1 0 1 1 1 0 Phosphoinositide 3-kinase C2 V-ATPase_G_2 PF16999.5 KFM58322.1 - 1.1 9.7 10.7 0.74 10.3 0.7 2.4 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Amidase PF01425.21 KFM58323.1 - 1.7e-53 182.2 0.2 2.1e-53 181.9 0.2 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KFM58324.1 - 1.8e-31 109.6 0.0 2.3e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KFM58326.1 - 9.6e-74 248.9 0.0 1.2e-73 248.7 0.0 1.1 1 0 0 1 1 1 1 Amidase FAD_binding_1 PF00667.20 KFM58328.1 - 1.2e-64 217.9 0.1 1.6e-64 217.5 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFM58328.1 - 1.8e-39 135.2 0.6 3.6e-39 134.2 0.6 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KFM58328.1 - 0.17 12.1 0.0 0.77 10.0 0.0 2.1 2 1 0 2 2 2 0 Flavodoxin domain 7tm_1 PF00001.21 KFM58329.1 - 2.8e-28 99.0 16.7 3.6e-28 98.6 16.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM58329.1 - 6e-06 25.8 13.9 8.3e-06 25.4 13.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM58329.1 - 0.00011 21.9 17.1 0.00016 21.4 17.1 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Ceramidase PF05875.12 KFM58330.1 - 4e-54 183.8 10.3 4.6e-54 183.6 10.3 1.0 1 0 0 1 1 1 1 Ceramidase ASFV_L11L PF05293.11 KFM58330.1 - 6.6 7.1 8.5 4.4 7.7 0.1 3.3 3 0 0 3 3 3 0 African swine fever virus (ASFV) L11L protein EF-hand_1 PF00036.32 KFM58331.1 - 4.3e-28 94.7 14.9 9.6e-07 27.9 0.3 4.6 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KFM58331.1 - 7.9e-26 90.3 4.6 4.3e-14 52.7 0.5 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM58331.1 - 8.8e-22 75.6 8.7 1.8e-05 24.0 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFM58331.1 - 2.3e-21 73.8 6.4 3.5e-05 23.4 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFM58331.1 - 6.3e-17 61.2 8.7 0.0028 17.4 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM58331.1 - 1e-08 35.4 0.4 0.0016 18.7 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFM58331.1 - 4e-08 33.1 5.6 0.003 17.5 0.2 3.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFM58331.1 - 0.0012 19.2 0.2 0.23 11.8 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 KFM58331.1 - 0.0057 16.6 3.9 16 5.3 0.1 3.8 2 2 2 4 4 4 1 Caleosin related protein DUF1398 PF07166.11 KFM58331.1 - 0.036 14.1 0.1 0.33 11.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1398) Synaphin PF05835.12 KFM58333.1 - 2.6e-06 27.7 1.0 2.8e-06 27.7 1.0 1.0 1 0 0 1 1 1 1 Synaphin protein PDEase_I PF00233.19 KFM58334.1 - 0.00013 21.8 0.5 0.00018 21.3 0.5 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 KFM58335.1 - 2.8e-57 194.2 0.0 3.8e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase pPIWI_RE_Y PF18156.1 KFM58335.1 - 0.11 12.9 0.2 4.2 7.8 0.0 2.7 3 0 0 3 3 3 0 pPIWI_RE three-gene island domain Y Ank_2 PF12796.7 KFM58336.1 - 1.5e-12 47.9 1.3 1.2e-07 32.2 0.0 3.0 3 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM58336.1 - 4.3e-11 43.1 0.0 9.3e-06 26.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 KFM58336.1 - 8.6e-11 41.7 12.8 1.7e-10 40.8 12.8 1.5 1 0 0 1 1 1 1 MYND finger Ank PF00023.30 KFM58336.1 - 9.2e-10 38.5 0.2 4.6e-05 23.7 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFM58336.1 - 9.2e-09 34.9 0.7 2.5e-05 24.3 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KFM58336.1 - 9e-06 25.9 0.2 0.025 14.9 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PolC_DP2 PF03833.13 KFM58336.1 - 0.044 11.6 3.6 0.062 11.2 3.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 KFM58336.1 - 1 9.7 11.5 2.3 8.6 11.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-ribbon_3 PF13248.6 KFM58336.1 - 1.5 8.3 8.1 30 4.2 8.1 3.2 1 1 0 1 1 1 0 zinc-ribbon domain EAP30 PF04157.16 KFM58339.1 - 4.3e-70 235.7 0.1 4.9e-70 235.5 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family ANAPC4 PF12896.7 KFM58339.1 - 0.0038 16.7 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 tRNA-synt_1 PF00133.22 KFM58340.1 - 1.1e-174 582.1 3.0 2e-173 577.9 3.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFM58340.1 - 1.3e-14 53.8 15.4 5.2e-09 35.3 0.9 4.0 4 1 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KFM58340.1 - 2.9e-09 36.7 0.0 1.2e-06 28.2 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KFM58340.1 - 0.00037 20.0 0.0 0.066 12.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 KFM58340.1 - 0.019 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) Anticodon_1 PF08264.13 KFM58341.1 - 2.3e-32 112.1 0.0 4.5e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 KFM58341.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm DUF4686 PF15742.5 KFM58342.1 - 0.059 12.5 78.1 0.024 13.8 48.2 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) AAA_25 PF13481.6 KFM58342.1 - 0.063 12.8 1.3 5.1 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF3367 PF11847.8 KFM58342.1 - 0.087 10.7 0.3 0.13 10.1 0.3 1.2 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase ER PF01133.17 KFM58342.1 - 0.1 12.6 0.2 0.1 12.6 0.2 2.9 3 0 0 3 3 3 0 Enhancer of rudimentary YqgF PF14639.6 KFM58342.1 - 1.6 8.5 5.3 1.2 8.9 0.5 2.6 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 DUF730 PF05325.11 KFM58342.1 - 2.2 8.3 10.4 2.7 8.0 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF730) FliD_C PF07195.12 KFM58342.1 - 2.3 7.6 27.4 0.16 11.4 13.1 3.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus APOBEC_C PF05240.14 KFM58342.1 - 5 7.2 7.8 2 8.4 0.1 3.7 3 1 1 4 4 4 0 APOBEC-like C-terminal domain 7tm_3 PF00003.22 KFM58343.1 - 4.2e-58 196.9 17.5 6.1e-58 196.4 17.5 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFM58343.1 - 7e-12 45.1 10.0 7e-12 45.1 10.0 2.4 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR DUF1418 PF07214.12 KFM58343.1 - 0.17 11.8 0.6 2.8 7.9 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) FixQ PF05545.11 KFM58343.1 - 0.85 9.6 4.2 29 4.7 0.1 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ ANF_receptor PF01094.28 KFM58344.1 - 2e-16 60.1 0.0 2.3e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region GLTP PF08718.11 KFM58348.1 - 0.013 15.8 0.6 0.015 15.6 0.6 1.1 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) PAP2 PF01569.21 KFM58348.1 - 0.027 14.2 0.1 0.034 13.9 0.1 1.1 1 0 0 1 1 1 0 PAP2 superfamily Mito_carr PF00153.27 KFM58349.1 - 3.9e-68 225.4 0.4 5.1e-24 84.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1179 PF06678.11 KFM58350.1 - 0.19 11.8 2.8 0.43 10.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Atrophin-1 PF03154.15 KFM58351.1 - 0.12 10.6 8.4 0.14 10.4 8.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family TPR_1 PF00515.28 KFM58352.1 - 3.8e-42 140.4 42.2 3.8e-05 23.3 0.0 14.6 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 KFM58352.1 - 6.7e-41 138.7 10.1 9.6e-07 29.2 0.0 9.9 8 2 3 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 KFM58352.1 - 2e-40 133.7 42.9 0.00037 20.4 0.1 15.5 16 0 0 16 16 14 9 Tetratricopeptide repeat TPR_14 PF13428.6 KFM58352.1 - 6.1e-33 110.7 14.3 0.057 14.3 0.0 14.5 9 4 6 15 15 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 KFM58352.1 - 2.6e-32 108.3 25.6 0.00044 20.2 0.0 13.5 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFM58352.1 - 3.7e-28 97.9 15.8 4.8e-05 23.9 0.1 11.0 9 2 2 11 11 11 8 Tetratricopeptide repeat TPR_12 PF13424.6 KFM58352.1 - 3.2e-26 91.4 36.1 6.1e-06 26.4 2.1 11.2 6 3 2 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFM58352.1 - 5e-22 76.7 21.9 1.3 9.6 0.1 16.0 18 1 1 19 19 16 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM58352.1 - 1.1e-20 73.0 24.2 7.8e-05 22.3 0.0 11.8 10 3 3 13 13 12 6 TPR repeat TPR_7 PF13176.6 KFM58352.1 - 5.1e-20 70.0 29.0 0.032 14.3 0.3 12.4 14 0 0 14 14 12 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFM58352.1 - 4.1e-15 55.1 26.2 0.0075 16.1 0.4 12.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_6 PF13174.6 KFM58352.1 - 4.6e-13 48.9 36.4 0.09 13.4 0.0 13.1 15 0 0 15 15 13 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM58352.1 - 3.6e-05 23.9 35.0 0.059 13.6 0.1 7.5 7 1 1 9 9 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFM58352.1 - 0.00044 20.3 23.6 0.9 9.7 0.1 8.4 7 2 1 9 9 8 3 Tetratricopeptide repeat NARP1 PF12569.8 KFM58352.1 - 0.00081 18.4 2.8 0.00081 18.4 2.8 8.5 4 2 4 8 8 3 1 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KFM58352.1 - 0.0012 19.3 1.7 44 5.1 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFM58352.1 - 0.027 14.4 18.3 11 6.2 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM58352.1 - 0.21 11.7 17.6 4.5 7.4 0.1 7.6 7 1 1 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat MMS1_N PF10433.9 KFM58353.1 - 1e-07 31.0 0.0 1.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term MULE PF10551.9 KFM58354.1 - 0.025 15.0 0.5 0.18 12.3 0.1 2.0 1 1 0 2 2 2 0 MULE transposase domain PvlArgDC PF01862.16 KFM58355.1 - 0.08 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Pkinase PF00069.25 KFM58356.1 - 1.9e-17 63.5 0.0 3.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM58356.1 - 1.8e-09 37.3 0.0 3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KFM58356.1 - 0.069 13.4 0.1 0.82 10.1 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat DUF1981 PF09324.10 KFM58356.1 - 2.3 8.1 4.6 18 5.3 0.2 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF1981) SNF PF00209.18 KFM58358.1 - 7.1e-211 701.4 36.1 9e-211 701.1 36.1 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family TIL PF01826.17 KFM58358.1 - 0.014 15.7 0.6 0.027 14.7 0.6 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DUF885 PF05960.11 KFM58359.1 - 2.6e-118 397.0 0.0 2.9e-118 396.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF885 PF05960.11 KFM58360.1 - 1.3e-13 51.5 0.0 1.5e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF885 PF05960.11 KFM58361.1 - 1.5e-143 480.2 0.9 1.8e-143 480.0 0.9 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF2802 PF10975.8 KFM58363.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Glyco_hydro_47 PF01532.20 KFM58364.1 - 8e-67 226.1 0.0 9.1e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2929 PF11151.8 KFM58364.1 - 0.16 12.3 1.0 0.29 11.4 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2929) Glyco_hydro_47 PF01532.20 KFM58365.1 - 4.2e-43 147.9 0.2 1.1e-42 146.5 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KFM58365.1 - 4.9e-05 23.3 0.2 9e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 PA domain Fib_alpha PF08702.10 KFM58366.1 - 0.043 14.0 3.7 0.079 13.1 3.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Serpin PF00079.20 KFM58368.1 - 1.6e-109 366.7 4.6 1.8e-109 366.5 4.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFM58369.1 - 5.3e-91 305.7 6.6 5.9e-91 305.5 6.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) ArsR PF09824.9 KFM58369.1 - 0.28 10.8 3.9 0.16 11.6 0.8 2.1 2 2 1 3 3 3 0 ArsR transcriptional regulator Serpin PF00079.20 KFM58370.1 - 1.8e-119 399.4 16.7 1.4e-93 314.1 10.9 2.0 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) DUF5388 PF17363.2 KFM58370.1 - 0.00014 22.0 0.0 0.31 11.3 0.0 3.0 2 0 0 2 2 2 2 Family of unknown function (DUF5388) ABC1 PF03109.16 KFM58370.1 - 0.00052 20.2 3.1 0.091 12.9 0.2 3.0 3 0 0 3 3 3 2 ABC1 family Ubiq_cyt_C_chap PF03981.12 KFM58370.1 - 0.02 15.0 0.1 0.066 13.3 0.1 1.9 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Serpin PF00079.20 KFM58371.1 - 3e-102 342.7 5.0 3.3e-102 342.6 5.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1981 PF09324.10 KFM58371.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) ABC1 PF03109.16 KFM58371.1 - 0.18 12.0 0.5 0.84 9.8 0.1 2.1 2 0 0 2 2 2 0 ABC1 family SAC3_GANP PF03399.16 KFM58372.1 - 6.6e-32 111.1 0.3 1.2e-31 110.2 0.3 1.4 1 0 0 1 1 1 1 SAC3/GANP family ALMT PF11744.8 KFM58372.1 - 0.28 10.0 6.0 0.3 9.8 6.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SAC3_GANP PF03399.16 KFM58373.1 - 1.3e-41 142.9 2.4 1.4e-41 142.8 2.4 1.0 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KFM58373.1 - 2.8e-05 24.1 0.9 4.2e-05 23.5 0.9 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TF_AP-2 PF03299.14 KFM58373.1 - 0.031 14.2 0.1 0.045 13.7 0.0 1.4 1 1 0 1 1 1 0 Transcription factor AP-2 DNA_primase_lrg PF04104.14 KFM58376.1 - 1.2e-93 313.4 0.2 1.9e-93 312.7 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit SusD_RagB PF07980.11 KFM58376.1 - 0.14 11.8 1.9 0.14 11.7 0.4 1.7 2 0 0 2 2 2 0 SusD family LMBR1 PF04791.16 KFM58377.1 - 6.1e-18 65.0 7.3 6.1e-18 65.0 7.3 2.5 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF3149 PF11346.8 KFM58377.1 - 0.14 11.8 0.1 0.14 11.8 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) GAF PF01590.26 KFM58379.1 - 0.00029 21.5 0.0 0.00031 21.4 0.0 1.0 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KFM58379.1 - 0.065 13.5 0.0 0.071 13.4 0.0 1.1 1 0 0 1 1 1 0 GAF domain GAF PF01590.26 KFM58380.1 - 5.6e-05 23.8 0.0 7.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KFM58380.1 - 0.0064 16.8 0.0 0.0083 16.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 KFM58380.1 - 0.044 13.8 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor GAF_3 PF13492.6 KFM58380.1 - 0.095 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 GAF domain PDEase_I PF00233.19 KFM58381.1 - 7.7e-23 81.4 0.0 1e-22 81.0 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FKBP_C PF00254.28 KFM58382.1 - 7.7e-35 119.1 0.0 9e-35 118.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cnn_1N PF07989.11 KFM58384.1 - 9e-17 61.0 6.2 9e-17 61.0 6.2 4.5 2 2 3 5 5 5 1 Centrosomin N-terminal motif 1 MPS2 PF17060.5 KFM58384.1 - 0.011 15.1 4.9 0.011 15.1 4.9 3.0 2 1 1 3 3 3 0 Monopolar spindle protein 2 ATG16 PF08614.11 KFM58384.1 - 0.17 12.1 38.8 1.8 8.7 9.9 3.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Sec34 PF04136.15 KFM58384.1 - 0.19 11.6 22.5 0.74 9.7 0.4 4.0 3 1 1 4 4 4 0 Sec34-like family MIT PF04212.18 KFM58384.1 - 0.27 11.3 0.0 0.27 11.3 0.0 4.1 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain UPF0184 PF03670.13 KFM58384.1 - 0.97 9.9 9.7 0.18 12.2 2.6 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) PilJ PF13675.6 KFM58384.1 - 2.2 8.4 12.7 5.5 7.0 0.2 4.4 3 2 0 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4446 PF14584.6 KFM58384.1 - 2.3 8.2 21.9 1.8 8.5 2.2 4.6 3 2 1 4 4 4 0 Protein of unknown function (DUF4446) DUF948 PF06103.11 KFM58384.1 - 3.3 8.0 16.2 2.2 8.6 0.6 4.8 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 KFM58384.1 - 4.3 7.4 38.1 8.1 6.5 6.7 4.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein KELK PF15796.5 KFM58384.1 - 9.9 6.7 31.4 0.67 10.4 2.7 4.8 4 1 0 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NDUFA12 PF05071.16 KFM58385.1 - 1.1e-10 42.3 1.2 1.5e-10 41.8 1.2 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4880 PF16220.5 KFM58385.1 - 0.0081 16.0 1.6 0.013 15.4 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) DUF1451 PF07295.11 KFM58387.1 - 0.042 13.9 0.1 0.042 13.9 0.1 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF4752 PF15944.5 KFM58387.1 - 0.091 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) CHIP_TPR_N PF18391.1 KFM58387.1 - 3.2 8.6 11.6 1.3 9.8 2.4 2.3 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain DUF3381 PF11861.8 KFM58387.1 - 3.8 7.3 14.7 1 9.1 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF5523 PF17661.1 KFM58388.1 - 1e-19 71.2 0.7 1.6e-19 70.6 0.0 1.7 2 1 0 2 2 2 1 Family of unknown function (DUF5523) DUF4201 PF13870.6 KFM58388.1 - 0.026 14.2 4.8 0.048 13.4 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF3232 PF11554.8 KFM58388.1 - 0.03 14.7 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) CC2D2AN-C2 PF15625.6 KFM58389.1 - 4.1e-38 130.8 0.0 6.1e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain JHD PF17811.1 KFM58389.1 - 0.019 15.5 1.6 0.019 15.5 1.6 1.9 2 0 0 2 2 2 0 Jumonji helical domain Glycohydro_20b2 PF14845.6 KFM58389.1 - 0.024 15.3 0.5 0.071 13.8 0.0 1.9 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like C2 PF00168.30 KFM58390.1 - 6e-05 23.3 0.0 0.00024 21.4 0.0 2.1 1 1 0 1 1 1 1 C2 domain IPK PF03770.16 KFM58391.1 - 2.1e-07 31.0 0.0 2.2e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase IPK PF03770.16 KFM58392.1 - 8.7e-32 110.6 0.0 1e-31 110.4 0.0 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase NUDIX PF00293.28 KFM58394.1 - 1.2e-19 70.7 0.5 1.6e-19 70.3 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain Arf PF00025.21 KFM58396.1 - 4.3e-46 156.5 0.1 5.3e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFM58396.1 - 4.5e-14 52.4 0.0 5.4e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM58396.1 - 3.6e-13 49.8 0.1 5.3e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFM58396.1 - 5.1e-13 48.9 0.3 2.3e-09 36.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFM58396.1 - 6.3e-08 32.3 0.0 7.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFM58396.1 - 1e-07 32.0 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM58396.1 - 2e-07 30.6 0.0 2.4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM58396.1 - 0.00032 20.3 0.1 0.002 17.7 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF389 PF04087.14 KFM58397.1 - 3.8e-41 140.5 4.5 3.8e-41 140.5 4.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF389) Pex24p PF06398.11 KFM58397.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MFS_1 PF07690.16 KFM58399.1 - 0.00025 20.1 9.7 0.00031 19.8 9.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFM58399.1 - 0.0059 15.2 5.2 0.0072 14.9 5.2 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein DUF4538 PF15061.6 KFM58399.1 - 8.3 6.2 10.8 0.24 11.2 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) MFS_1 PF07690.16 KFM58400.1 - 1e-13 51.0 8.2 1.1e-11 44.3 7.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFM58400.1 - 3e-07 29.1 2.8 3.9e-05 22.2 0.2 2.2 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_A8 PF01252.18 KFM58400.1 - 0.18 12.1 1.9 0.28 11.4 0.6 1.9 1 1 0 1 1 1 0 Signal peptidase (SPase) II MFS_1 PF07690.16 KFM58401.1 - 1.6e-09 37.2 14.4 2e-09 36.9 14.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFM58402.1 - 0.0056 15.7 2.0 0.0064 15.5 2.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFM58404.1 - 1.2e-09 37.6 10.0 1.3e-09 37.4 10.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4203 PF13886.6 KFM58404.1 - 0.42 10.2 13.0 0.55 9.9 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) MFS_1 PF07690.16 KFM58405.1 - 9.3e-10 37.9 5.1 1.1e-09 37.7 5.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KFM58405.1 - 0.0049 15.2 0.5 0.0049 15.2 0.5 1.8 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Peptidase_A24 PF01478.18 KFM58405.1 - 0.0074 16.7 6.4 0.0074 16.7 6.4 1.8 1 1 1 2 2 2 1 Type IV leader peptidase family Peptidase_A8 PF01252.18 KFM58405.1 - 1.5 9.1 6.0 0.58 10.4 1.7 2.0 1 1 1 2 2 2 0 Signal peptidase (SPase) II DUF2070 PF09843.9 KFM58405.1 - 2.1 6.5 11.4 2.8 6.1 11.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 KFM58406.1 - 3.1e-26 92.2 20.5 1.1e-25 90.3 20.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily RabGAP-TBC PF00566.18 KFM58408.1 - 8.7e-55 185.7 2.7 1.6e-54 184.8 2.7 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FTA2 PF13095.6 KFM58408.1 - 0.075 12.6 0.3 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF2434 PF10361.9 KFM58409.1 - 0.024 13.6 0.1 0.024 13.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) RRM_1 PF00076.22 KFM58410.1 - 8.1e-46 153.7 0.6 6.4e-17 61.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 KFM58410.1 - 4.6e-30 103.4 0.0 2.1e-29 101.3 0.0 2.1 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 KFM58410.1 - 2.7e-08 33.8 0.1 0.0045 17.1 0.0 4.1 3 1 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 KFM58410.1 - 2.1e-07 30.6 0.0 8.3e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFM58410.1 - 8e-05 22.6 0.3 0.19 11.8 0.0 3.3 2 2 1 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 KFM58410.1 - 0.00026 20.8 0.0 0.027 14.3 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KFM58410.1 - 0.002 18.4 0.7 3.6 7.8 0.0 3.5 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KFM58410.1 - 0.0079 16.2 0.6 0.061 13.4 0.3 2.2 2 0 0 2 2 2 1 RNA binding motif SET_assoc PF11767.8 KFM58410.1 - 0.013 15.1 0.2 0.25 11.0 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated DUF5115 PF17142.4 KFM58410.1 - 0.078 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5115) MFS_1 PF07690.16 KFM58411.1 - 4.7e-16 58.7 8.2 5.8e-16 58.4 8.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFM58411.1 - 8e-05 22.1 0.8 0.00011 21.6 0.8 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KFM58411.1 - 0.00061 18.5 7.3 0.00061 18.5 7.3 1.6 1 1 1 2 2 2 1 MFS/sugar transport protein HupE_UreJ_2 PF13795.6 KFM58411.1 - 0.091 12.4 0.2 0.091 12.4 0.2 1.6 2 0 0 2 2 2 0 HupE / UreJ protein DUF3953 PF13129.6 KFM58411.1 - 0.66 9.8 6.5 16 5.4 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3953) DUF2244 PF10003.9 KFM58411.1 - 4 7.1 5.6 7.5 6.2 1.9 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) SAM_1 PF00536.30 KFM58412.1 - 4.7e-14 52.6 0.1 5.9e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM58412.1 - 2.6e-10 40.3 0.0 2.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 KFM58412.1 - 0.0063 16.5 0.6 0.011 15.7 0.4 1.6 1 1 1 2 2 2 1 NAB conserved region 1 (NCD1) BTB PF00651.31 KFM58413.1 - 4.5e-34 117.0 2.2 5.9e-34 116.6 0.5 2.0 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 KFM58413.1 - 9.3e-07 29.0 0.1 2.5e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 MATH domain BACK PF07707.15 KFM58413.1 - 0.00059 19.9 0.7 0.24 11.5 0.0 3.6 2 1 1 3 3 3 1 BTB And C-terminal Kelch Skp1_POZ PF03931.15 KFM58413.1 - 0.0011 19.1 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DDE_Tnp_IS1595 PF12762.7 KFM58414.1 - 0.0011 19.0 0.1 0.0014 18.6 0.1 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain Asp_protease_2 PF13650.6 KFM58415.1 - 0.0016 19.0 0.0 0.0024 18.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM58415.1 - 0.0057 17.2 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Phage_glycop_gL PF11108.8 KFM58415.1 - 0.0091 16.0 0.2 0.012 15.6 0.2 1.2 1 0 0 1 1 1 1 Viral glycoprotein L DUF1758 PF05585.12 KFM58415.1 - 0.025 14.3 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DEAD PF00270.29 KFM58417.1 - 4.5e-46 156.8 0.1 8.3e-46 155.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM58417.1 - 1.3e-26 93.1 0.6 5.1e-26 91.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM58417.1 - 1.9e-09 37.7 0.0 7.2e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFM58417.1 - 0.0025 17.5 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KFM58417.1 - 0.032 14.5 0.5 0.15 12.3 0.5 2.2 1 1 0 1 1 1 0 AAA domain TPR_2 PF07719.17 KFM58418.1 - 6e-16 57.2 10.7 0.17 12.1 0.0 8.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFM58418.1 - 1.5e-12 46.8 11.0 0.042 13.7 0.1 8.2 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM58418.1 - 3.4e-10 40.1 7.7 0.16 12.3 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM58418.1 - 2e-08 34.6 0.8 0.15 12.6 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM58418.1 - 4.9e-08 33.1 10.7 0.11 12.8 0.1 6.2 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFM58418.1 - 8.9e-07 28.6 0.8 0.12 12.3 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM58418.1 - 4e-06 26.6 10.2 0.33 11.3 0.2 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KFM58418.1 - 1.2e-05 24.9 0.5 0.6 9.5 0.0 3.5 2 1 1 3 3 3 2 Coatomer epsilon subunit TPR_14 PF13428.6 KFM58418.1 - 9.7e-05 22.9 0.7 1 10.4 0.0 5.4 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM58418.1 - 0.00026 20.8 0.0 0.72 10.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFM58418.1 - 0.00068 19.6 5.0 0.56 10.2 0.2 3.7 3 1 0 3 3 3 2 Putative TPR-like repeat TPR_6 PF13174.6 KFM58418.1 - 0.0016 18.9 16.0 25 5.8 0.3 7.2 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM58418.1 - 0.0032 18.1 0.1 16 6.2 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFM58418.1 - 0.0086 16.4 1.3 30 5.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 KFM58418.1 - 0.031 14.0 0.5 1.1 9.0 0.3 3.3 2 1 2 4 4 4 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 KFM58418.1 - 0.12 12.5 3.8 57 3.9 0.0 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Fumble PF03630.14 KFM58418.1 - 0.53 9.4 2.7 0.48 9.6 0.3 1.9 2 0 0 2 2 2 0 Fumble TPR_17 PF13431.6 KFM58418.1 - 1.5 9.4 9.0 66 4.2 0.1 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat DDE_Tnp_1_7 PF13843.6 KFM58420.1 - 1.5e-56 192.2 0.1 1.9e-56 191.9 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM58420.1 - 2.7 8.9 8.8 4.4 8.2 5.9 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon PAP2 PF01569.21 KFM58421.1 - 3.6e-24 85.1 1.7 5.7e-24 84.4 1.7 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFM58421.1 - 0.00069 19.4 1.0 0.0054 16.4 1.0 2.1 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFM58421.1 - 0.021 15.3 4.0 0.079 13.5 4.0 2.0 1 1 0 1 1 1 0 PAP2 superfamily C-terminal YoqO PF14037.6 KFM58421.1 - 0.022 15.3 0.8 0.022 15.3 0.8 1.8 2 0 0 2 2 2 0 YoqO-like protein An_peroxidase PF03098.15 KFM58424.1 - 1.3e-118 396.9 0.1 1.7e-118 396.6 0.1 1.0 1 0 0 1 1 1 1 Animal haem peroxidase SSXT PF05030.12 KFM58425.1 - 1.4e-23 82.3 0.0 2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Abdominal-A PF12407.8 KFM58426.1 - 1e-07 31.4 5.3 1e-07 31.4 5.3 1.8 2 1 0 2 2 2 1 Homeobox protein Bac_export_2 PF01312.19 KFM58426.1 - 0.71 9.0 2.5 0.82 8.8 2.5 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Gly_rich PF12810.7 KFM58428.1 - 3.3e-05 23.9 0.2 4e-05 23.7 0.2 1.0 1 0 0 1 1 1 1 Glycine rich protein Pkinase_Tyr PF07714.17 KFM58430.1 - 1.2e-24 87.0 0.0 1.5e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM58430.1 - 6.1e-13 48.7 0.0 8.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ycf66_N PF07444.11 KFM58430.1 - 0.066 13.3 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Ycf66 protein N-terminus Pkinase_Tyr PF07714.17 KFM58431.1 - 6.5e-39 133.8 0.0 8.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM58431.1 - 1.6e-07 30.9 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain NusG_II PF07009.11 KFM58432.1 - 0.057 13.6 0.1 0.063 13.5 0.1 1.1 1 0 0 1 1 1 0 NusG domain II zf-H2C2_2 PF13465.6 KFM58433.1 - 2.4e-95 309.1 103.8 7.2e-09 35.7 1.8 16.1 16 0 0 16 16 16 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58433.1 - 1.1e-59 195.6 116.9 4.4e-05 23.7 0.6 15.1 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58433.1 - 7.8e-53 172.5 113.1 0.00056 20.5 0.6 15.1 15 0 0 15 15 15 15 C2H2-type zinc finger zf-met PF12874.7 KFM58433.1 - 3.6e-30 103.4 96.3 0.003 17.9 0.1 15.2 15 0 0 15 15 15 13 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM58433.1 - 3.1e-23 81.3 98.2 0.06 13.4 0.5 16.3 15 2 0 15 15 15 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM58433.1 - 9.9e-23 79.9 73.5 0.04 14.2 0.2 15.6 13 3 2 15 15 15 10 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM58433.1 - 9e-12 45.1 15.6 0.078 13.3 0.0 9.1 2 1 7 9 9 9 4 BolA-like protein zf-H2C2_5 PF13909.6 KFM58433.1 - 5.7e-05 22.8 68.1 0.0029 17.3 0.5 13.3 15 0 0 15 15 15 5 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM58433.1 - 0.00012 22.1 54.6 1.6 8.8 1.0 12.8 10 3 4 14 14 14 3 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM58433.1 - 0.00014 21.7 57.3 0.48 10.4 0.3 12.3 13 0 0 13 13 13 4 zinc-finger of a C2HC-type Baculo_IE-1 PF05290.11 KFM58433.1 - 0.00026 21.0 46.1 0.12 12.3 0.3 10.9 1 1 8 10 10 10 1 Baculovirus immediate-early protein (IE-0) zf-C2H2_2 PF12756.7 KFM58433.1 - 0.0018 18.6 86.4 0.16 12.3 4.9 13.0 1 1 11 12 12 12 2 C2H2 type zinc-finger (2 copies) Ta0938 PF11494.8 KFM58433.1 - 0.003 17.8 27.9 3.5 7.9 0.0 8.7 3 3 6 9 9 9 2 Ta0938 zinc_ribbon_15 PF17032.5 KFM58433.1 - 0.014 16.1 54.0 2.3 9.0 1.7 7.7 2 2 6 8 8 8 0 zinc-ribbon family FYVE PF01363.21 KFM58433.1 - 0.023 14.8 76.3 0.34 11.1 5.3 8.9 2 2 7 9 9 9 0 FYVE zinc finger zf-MYST PF17772.1 KFM58433.1 - 0.03 13.9 53.9 0.91 9.2 0.1 12.2 8 4 5 13 13 13 0 MYST family zinc finger domain zf_UBZ PF18439.1 KFM58433.1 - 0.042 13.4 56.5 2.5 7.8 0.4 13.3 14 0 0 14 14 14 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFM58433.1 - 0.12 12.2 0.1 0.12 12.2 0.1 12.6 15 0 0 15 15 13 0 zinc-finger C2H2-type DNA_pol_B_2 PF03175.13 KFM58434.1 - 4.1e-06 25.9 1.6 6.5e-06 25.3 1.6 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Suv3_N PF18114.1 KFM58434.1 - 0.0032 17.6 0.4 4.5 7.4 0.2 2.9 2 1 1 3 3 3 2 Suv3 helical N-terminal domain DUF2854 PF11016.8 KFM58434.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) EGF PF00008.27 KFM58435.1 - 1.2e-23 83.1 223.8 4.1e-08 33.4 5.9 19.2 18 2 0 18 18 18 12 EGF-like domain EGF_CA PF07645.15 KFM58435.1 - 9.9e-11 41.7 5.9 9.9e-11 41.7 5.9 18.3 11 5 6 17 17 17 5 Calcium-binding EGF domain cEGF PF12662.7 KFM58435.1 - 4.4e-07 29.7 16.0 0.00054 19.8 1.0 15.2 14 0 0 14 14 14 7 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 KFM58435.1 - 2.4e-06 27.5 5.6 2.4e-06 27.5 5.6 15.4 16 0 0 16 16 16 1 MSP1 EGF domain 1 EGF_3 PF12947.7 KFM58435.1 - 7.2e-05 22.9 4.3 7.2e-05 22.9 4.3 19.1 17 2 1 18 18 18 8 EGF domain FXa_inhibition PF14670.6 KFM58435.1 - 7.9e-05 22.9 234.3 0.0041 17.4 5.3 20.0 14 4 4 18 18 18 11 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFM58435.1 - 0.00092 19.8 14.7 0.0027 18.3 3.8 20.2 19 3 0 19 19 19 8 Human growth factor-like EGF EGF_2 PF07974.13 KFM58435.1 - 0.004 17.5 9.6 0.004 17.5 9.6 18.4 18 2 1 19 19 19 6 EGF-like domain Glycophorin_A PF01102.18 KFM58435.1 - 0.38 11.0 2.1 0.57 10.4 0.0 2.3 2 0 0 2 2 2 0 Glycophorin A EGF_2 PF07974.13 KFM58436.1 - 0.041 14.3 11.8 0.041 14.3 11.8 3.0 3 0 0 3 3 3 0 EGF-like domain CS PF04969.16 KFM58441.1 - 7.8e-06 26.8 0.1 1.6e-05 25.8 0.0 1.6 2 0 0 2 2 2 1 CS domain 2TM PF13239.6 KFM58443.1 - 0.18 12.2 0.2 4.5 7.7 0.0 2.2 2 0 0 2 2 2 0 2TM domain Importin_rep_2 PF18786.1 KFM58443.1 - 0.89 9.4 3.4 4.2 7.3 0.2 2.8 2 0 0 2 2 2 0 Importin 13 repeat UQ_con PF00179.26 KFM58444.1 - 6.6e-41 139.2 0.5 8.5e-41 138.9 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFM58444.1 - 0.083 12.7 2.2 0.078 12.8 0.6 1.8 2 1 0 2 2 2 0 UEV domain RWD PF05773.22 KFM58444.1 - 0.15 12.3 1.3 0.25 11.6 1.3 1.7 1 1 0 1 1 1 0 RWD domain UPF0139 PF03669.13 KFM58445.1 - 7.2e-46 154.0 0.2 8.2e-46 153.8 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) protein_MS5 PF04776.12 KFM58445.1 - 0.14 12.2 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein MS5 CREPT PF16566.5 KFM58446.1 - 0.0059 16.8 5.1 0.0072 16.5 5.1 1.2 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour YabA PF06156.13 KFM58446.1 - 0.062 13.9 4.1 0.086 13.5 4.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Peptidase_S49_N PF08496.10 KFM58446.1 - 0.69 10.0 9.4 0.85 9.7 9.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LMBR1 PF04791.16 KFM58446.1 - 1.1 8.1 2.4 1.2 8.0 2.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein MULE PF10551.9 KFM58447.1 - 2.5e-16 59.8 0.8 2.1e-15 56.9 0.1 2.8 2 0 0 2 2 2 1 MULE transposase domain zf-C2H2 PF00096.26 KFM58447.1 - 0.0054 17.1 4.5 0.0054 17.1 4.5 4.7 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58447.1 - 0.01 16.6 3.6 0.01 16.6 3.6 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger Condensin2nSMC PF12422.8 KFM58447.1 - 0.063 13.5 1.1 0.79 9.9 0.2 2.7 1 1 1 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Ribosomal_S5_C PF03719.15 KFM58449.1 - 1.5e-08 34.0 0.0 2.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain LEDGF PF11467.8 KFM58452.1 - 7.5e-20 70.7 5.0 7.5e-20 70.7 5.0 3.9 4 2 0 4 4 4 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.17 KFM58452.1 - 9.3e-14 51.6 0.1 9.3e-14 51.6 0.1 7.3 4 1 1 5 5 5 1 PWWP domain Foie-gras_1 PF11817.8 KFM58453.1 - 2.8e-61 207.4 0.1 4.3e-61 206.8 0.1 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.12 KFM58453.1 - 1.5e-10 40.5 0.2 2e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 KFM58453.1 - 9.5e-10 38.3 0.0 2.3e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking RIBIOP_C PF04950.12 KFM58453.1 - 0.021 14.2 0.1 0.046 13.1 0.1 1.5 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Ribosomal_L20 PF00453.18 KFM58453.1 - 0.056 13.5 1.3 0.15 12.2 1.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 MIT PF04212.18 KFM58453.1 - 0.23 11.5 2.5 2.2 8.4 0.2 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Neur_chan_LBD PF02931.23 KFM58454.1 - 2.7e-45 154.5 0.8 4e-45 153.9 0.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM58454.1 - 0.00065 19.8 13.4 0.043 13.9 6.4 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Pre-PUA PF17832.1 KFM58454.1 - 0.1 13.3 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Pre-PUA-like domain Asn_synthase PF00733.21 KFM58455.1 - 2.3e-16 60.4 0.0 6.2e-06 26.1 0.0 3.3 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KFM58455.1 - 2.9e-06 27.2 0.0 0.0001 22.2 0.0 2.9 2 1 0 2 2 2 1 Glutamine amidotransferase domain zf-H2C2_2 PF13465.6 KFM58456.1 - 2.4e-39 132.0 58.6 4.3e-08 33.2 0.8 9.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58456.1 - 2.1e-27 94.0 72.2 0.0001 22.5 3.4 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58456.1 - 2.9e-25 86.8 68.1 0.0012 19.5 2.2 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM58456.1 - 2.2e-12 46.9 56.9 0.0015 18.9 0.6 8.2 9 0 0 9 9 7 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM58456.1 - 4.8e-08 32.6 47.6 0.017 14.8 1.4 8.2 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM58456.1 - 1.3e-05 25.3 40.2 0.019 15.2 0.5 8.0 8 1 0 8 8 7 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM58456.1 - 4.9e-05 23.5 48.0 0.0014 18.9 2.8 5.8 2 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFM58456.1 - 0.00019 21.6 8.4 0.21 11.9 0.4 4.8 2 1 1 4 4 4 1 BolA-like protein GAGA PF09237.11 KFM58456.1 - 0.00035 20.3 23.0 0.39 10.5 0.2 6.2 2 1 4 6 6 6 3 GAGA factor zf-C2H2_11 PF16622.5 KFM58456.1 - 0.00045 19.9 8.1 0.0091 15.7 0.6 6.9 7 2 0 7 7 5 3 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM58456.1 - 0.016 15.1 25.7 0.55 10.2 0.0 7.0 7 0 0 7 7 6 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 KFM58456.1 - 0.04 14.6 1.9 0.04 14.6 1.9 5.6 3 2 0 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_3 PF13878.6 KFM58456.1 - 0.061 13.2 0.3 0.061 13.2 0.3 5.7 4 2 2 6 6 6 0 zinc-finger of acetyl-transferase ESCO zf-Sec23_Sec24 PF04810.15 KFM58456.1 - 0.13 12.4 28.5 7.9 6.6 0.7 7.7 8 0 0 8 8 8 0 Sec23/Sec24 zinc finger TRAF6_Z2 PF18048.1 KFM58456.1 - 0.21 11.7 7.8 8.4 6.6 0.0 4.1 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-CHCC PF10276.9 KFM58456.1 - 0.23 11.6 10.5 2 8.5 0.0 4.8 6 0 0 6 6 5 0 Zinc-finger domain zf-C2H2_6 PF13912.6 KFM58456.1 - 0.38 10.8 0.2 0.38 10.8 0.2 9.9 9 3 0 9 9 8 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFM58456.1 - 0.52 10.5 26.1 1.7 8.8 0.8 5.1 3 2 2 5 5 5 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM58456.1 - 1.7 9.4 30.7 1.6 9.5 2.9 4.3 2 1 3 5 5 5 0 zinc-ribbon family Zf_RING PF16744.5 KFM58456.1 - 2.1 8.5 34.4 8.3 6.6 1.7 6.5 2 2 2 4 4 3 0 KIAA1045 RING finger Baculo_IE-1 PF05290.11 KFM58456.1 - 2.3 8.2 23.3 1.7 8.6 3.7 4.7 1 1 2 4 4 4 0 Baculovirus immediate-early protein (IE-0) HTH_5 PF01022.20 KFM58456.1 - 3.1 7.7 6.8 4.1 7.3 0.3 3.9 3 1 1 4 4 4 0 Bacterial regulatory protein, arsR family zf-H2C2_2 PF13465.6 KFM58457.1 - 4.8e-36 121.6 55.1 4.3e-08 33.2 0.4 8.3 9 0 0 9 9 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58457.1 - 2.1e-28 97.1 53.9 4e-05 23.8 0.7 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58457.1 - 3e-24 83.6 56.2 0.0013 19.4 0.6 8.0 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM58457.1 - 1.6e-11 44.2 49.5 0.013 15.8 0.2 8.0 8 1 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM58457.1 - 7.3e-08 32.6 36.0 8.9e-05 22.7 3.9 5.0 1 1 5 6 6 6 5 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFM58457.1 - 8.2e-08 32.4 51.9 0.0011 19.3 2.6 8.0 8 0 0 8 8 7 4 Zinc-finger of C2H2 type zinc_ribbon_9 PF14369.6 KFM58457.1 - 1.9e-05 24.8 7.9 9.7 6.5 0.1 6.1 6 0 0 6 6 6 0 zinc-ribbon zf_UBZ PF18439.1 KFM58457.1 - 0.00033 20.2 39.3 0.34 10.5 0.1 7.7 8 0 0 8 8 7 3 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM58457.1 - 0.00068 19.5 30.5 0.081 12.8 0.2 7.5 7 0 0 7 7 7 2 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM58457.1 - 0.00083 18.9 34.9 0.063 12.9 0.6 6.6 5 1 2 7 7 7 3 MYST family zinc finger domain zf-C2H2_6 PF13912.6 KFM58457.1 - 0.001 19.0 45.3 0.089 12.8 0.3 7.9 7 1 0 7 7 7 4 C2H2-type zinc finger BolA PF01722.18 KFM58457.1 - 0.0013 19.0 2.6 4 7.8 0.1 3.6 2 2 1 3 3 3 1 BolA-like protein Zn-ribbon_8 PF09723.10 KFM58457.1 - 0.003 17.6 30.3 0.11 12.6 0.8 6.4 4 2 2 6 6 6 2 Zinc ribbon domain zf-CCHC_2 PF13696.6 KFM58457.1 - 0.024 14.5 29.3 3.7 7.5 0.2 6.6 6 0 0 6 6 6 0 Zinc knuckle GAGA PF09237.11 KFM58457.1 - 0.06 13.2 14.4 0.41 10.5 1.6 4.8 2 2 2 4 4 4 0 GAGA factor zf-C2H2_2 PF12756.7 KFM58457.1 - 0.068 13.5 46.1 1 9.7 0.5 7.2 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 KFM58457.1 - 0.069 13.2 26.3 1.8e+04 -9.6 26.3 4.9 1 1 0 1 1 0 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFM58457.1 - 0.096 13.5 33.0 2.5 8.9 1.1 4.6 1 1 3 4 4 4 0 zinc-ribbon family Zn_ribbon_SprT PF17283.2 KFM58457.1 - 0.33 10.9 0.1 0.33 10.9 0.1 4.8 4 2 1 5 5 5 0 SprT-like zinc ribbon domain PRP21_like_P PF12230.8 KFM58457.1 - 0.42 10.4 13.8 2.8 7.8 2.3 3.6 1 1 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Prok-RING_2 PF14445.6 KFM58457.1 - 1.9 8.8 19.6 4.8 7.4 0.0 5.9 7 1 0 7 7 7 0 Prokaryotic RING finger family 2 ADK_lid PF05191.14 KFM58457.1 - 2.1 8.4 28.6 0.15 12.1 0.6 5.6 4 2 2 6 6 6 0 Adenylate kinase, active site lid TRAF6_Z2 PF18048.1 KFM58457.1 - 3.4 7.9 23.1 0.75 9.9 0.6 5.7 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_9 PF16293.5 KFM58457.1 - 5.9 6.8 24.7 1.3 8.9 0.3 6.3 4 2 3 7 7 7 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 KFM58457.1 - 7.5 6.7 43.3 1.1 9.3 1.1 6.8 1 1 4 5 5 5 0 BED zinc finger zf-H2C2_5 PF13909.6 KFM58457.1 - 8.9 6.2 42.3 1.4 8.7 3.3 7.2 7 0 0 7 7 7 0 C2H2-type zinc-finger domain CEBP1_N PF16368.5 KFM58458.1 - 0.013 15.0 2.7 0.064 12.8 2.7 2.0 1 1 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus PDZ PF00595.24 KFM58460.1 - 9.4e-15 54.7 0.1 2.5e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM58460.1 - 2.1e-13 49.9 0.3 3.6e-13 49.1 0.3 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM58460.1 - 2.5e-07 30.9 0.4 5.6e-07 29.8 0.1 1.7 2 0 0 2 2 2 1 PDZ domain EBP50_C PF09007.11 KFM58460.1 - 0.0031 18.5 10.8 0.004 18.1 4.0 2.2 1 1 1 2 2 2 1 EBP50, C-terminal GRASP55_65 PF04495.14 KFM58460.1 - 0.06 13.7 0.0 0.092 13.1 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain ABC_tran PF00005.27 KFM58461.1 - 5.3e-24 85.3 0.0 1.3e-23 84.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFM58461.1 - 1.7e-10 41.2 0.0 6.6e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KFM58461.1 - 0.00021 21.9 0.0 0.00035 21.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 KFM58461.1 - 0.026 14.3 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KFM58461.1 - 0.98 9.9 3.6 0.76 10.2 0.9 1.9 2 0 0 2 2 2 0 AAA domain LRR_8 PF13855.6 KFM58462.1 - 3.4e-22 78.0 12.8 3.6e-11 42.7 0.8 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFM58462.1 - 1.6e-15 57.0 7.5 7.3e-07 29.4 1.1 3.2 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM58462.1 - 8.9e-06 25.6 10.4 0.82 10.5 0.0 6.1 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 KFM58462.1 - 0.0088 15.6 1.0 0.25 10.8 0.4 2.2 1 1 1 2 2 2 1 Leucine-rich repeat LRR_5 PF13306.6 KFM58462.1 - 0.016 15.2 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFM58462.1 - 0.055 13.5 9.9 0.11 12.6 0.4 4.0 5 0 0 5 5 5 0 Leucine Rich repeat PDZ PF00595.24 KFM58466.1 - 5.2e-14 52.4 0.1 1.8e-13 50.6 0.1 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM58466.1 - 2.6e-09 37.3 0.1 4.8e-08 33.2 0.0 2.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFM58466.1 - 3.4e-07 30.0 0.2 3.1e-06 26.9 0.0 2.6 3 0 0 3 3 3 1 PDZ domain Pkinase PF00069.25 KFM58467.1 - 6.3e-11 42.1 0.0 7.9e-10 38.5 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Cnd1 PF12717.7 KFM58467.1 - 6.2e-10 39.4 0.0 4.2e-08 33.4 0.0 3.1 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 KFM58467.1 - 1.2e-08 34.6 0.0 6.2e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 KFM58467.1 - 1.8e-08 34.0 0.3 1.1 9.7 0.2 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KFM58467.1 - 9.5e-07 29.1 0.0 0.0018 18.6 0.0 3.1 2 1 3 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KFM58467.1 - 0.0066 16.9 0.5 2.7 8.6 0.1 3.5 3 1 0 3 3 3 1 HEAT-like repeat DUF832 PF05734.11 KFM58467.1 - 0.021 14.3 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) NDUF_B4 PF07225.12 KFM58468.1 - 5.3e-20 71.6 0.3 5.9e-20 71.4 0.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) PH PF00169.29 KFM58469.1 - 4.1e-13 49.7 0.0 1.7e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KFM58469.1 - 2.2e-07 31.0 0.1 4.3e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFM58469.1 - 2.1e-05 24.8 0.0 5.8e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KFM58469.1 - 0.0026 18.2 0.3 0.0098 16.3 0.3 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFM58469.1 - 0.0036 17.1 0.0 0.0095 15.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain MRP-S32 PF10210.9 KFM58469.1 - 0.046 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 stn_TNFRSF12A PF12191.8 KFM58469.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain betaPIX_CC PF16523.5 KFM58469.1 - 0.23 11.3 3.8 0.47 10.3 0.4 2.4 2 0 0 2 2 2 0 betaPIX coiled coil RNA_pol_Rpb5_N PF03871.14 KFM58470.1 - 2.6e-35 120.8 0.0 3.9e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 KFM58470.1 - 4.3e-07 29.7 1.5 1.5e-06 28.0 0.8 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain FumaraseC_C PF10415.9 KFM58470.1 - 0.054 13.9 0.3 0.47 10.9 0.0 2.4 3 0 0 3 3 3 0 Fumarase C C-terminus RNase_H PF00075.24 KFM58471.1 - 4.8e-08 33.3 0.1 1.1e-07 32.1 0.1 1.6 1 1 0 1 1 1 1 RNase H TBPIP PF07106.13 KFM58471.1 - 0.031 14.2 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain Toxin-deaminase PF14424.6 KFM58471.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases DnaJ PF00226.31 KFM58472.1 - 6.3e-27 93.5 3.4 1.4e-26 92.4 3.4 1.6 1 0 0 1 1 1 1 DnaJ domain zf_CCCH_4 PF18345.1 KFM58474.1 - 1.6e-06 27.9 3.6 2.6e-06 27.3 3.6 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFM58474.1 - 0.0012 18.7 3.5 0.0018 18.1 3.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFM58474.1 - 0.0023 18.6 7.6 0.0023 18.6 7.6 2.0 2 1 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 KFM58474.1 - 0.004 17.6 2.2 0.0066 16.9 2.2 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KFM58474.1 - 0.011 15.6 1.7 0.016 15.0 1.7 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger Spt5-NGN PF03439.13 KFM58475.1 - 1.1e-28 99.0 0.4 2.3e-28 97.9 0.4 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KFM58475.1 - 2.1e-14 54.3 10.1 2.1e-14 54.3 10.1 3.8 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KFM58475.1 - 6.3e-10 38.7 11.4 2.3e-07 30.5 0.1 5.0 5 1 0 5 5 5 3 KOW motif Med26_M PF15694.5 KFM58475.1 - 5.8 6.9 7.0 11 6.0 7.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain Ank PF00023.30 KFM58476.1 - 2.2e-07 31.0 0.0 2.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KFM58476.1 - 3.2e-05 24.0 0.1 0.00021 21.5 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KFM58476.1 - 0.00033 21.2 0.0 0.0004 20.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM58476.1 - 0.00058 20.4 0.1 0.057 14.0 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM58476.1 - 0.11 12.8 0.1 4.5 7.7 0.0 2.1 1 1 0 2 2 2 0 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 KFM58477.1 - 2.7e-29 98.5 12.9 2.5e-09 36.0 1.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFM58477.1 - 7.6e-28 96.8 9.7 8.8e-18 64.5 4.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM58477.1 - 7.8e-24 81.5 9.7 5.1e-08 32.2 0.0 4.6 3 1 2 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 KFM58477.1 - 1.8e-19 69.3 14.4 2.2e-12 46.6 3.3 4.0 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 KFM58477.1 - 2.3e-17 63.1 0.6 1.5e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFM58477.1 - 1.3e-11 43.4 12.0 9e-05 21.8 1.1 4.8 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 KFM58477.1 - 2.1e-07 30.9 3.0 0.0046 16.9 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KFM58477.1 - 0.00052 20.0 0.3 3.7 7.4 0.0 3.1 1 1 2 3 3 3 2 Caleosin related protein EF-hand_11 PF08976.11 KFM58477.1 - 0.0088 16.9 0.2 1.2 10.0 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain GPHH PF16905.5 KFM58477.1 - 0.024 14.4 0.0 0.9 9.4 0.0 2.8 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated DUF2059 PF09832.9 KFM58477.1 - 0.046 13.8 2.3 1 9.4 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) DUF2666 PF10869.8 KFM58477.1 - 0.051 13.8 1.0 1.6 8.9 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2666) SPARC_Ca_bdg PF10591.9 KFM58477.1 - 0.064 13.6 1.1 1.1 9.6 0.1 2.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ERAP1_C PF11838.8 KFM58477.1 - 0.066 12.7 0.0 6.7 6.2 0.0 2.1 1 1 0 2 2 2 0 ERAP1-like C-terminal domain DUF853 PF05872.12 KFM58477.1 - 0.1 11.2 0.1 0.21 10.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3349 PF11829.8 KFM58477.1 - 0.59 10.9 2.7 3.5 8.4 0.1 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) MgtE_N PF03448.17 KFM58477.1 - 2.7 8.6 8.2 3.1 8.5 1.3 2.5 1 1 1 2 2 2 0 MgtE intracellular N domain EF-hand_1 PF00036.32 KFM58478.1 - 1.4e-29 99.3 6.5 5.3e-10 38.1 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFM58478.1 - 6e-26 90.1 5.7 1.9e-13 50.0 1.0 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 KFM58478.1 - 6.7e-25 87.3 1.5 9e-18 64.5 0.6 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM58478.1 - 2.7e-19 67.4 3.7 1.1e-08 34.4 0.0 3.6 3 2 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFM58478.1 - 2.7e-18 64.6 2.3 1.7e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 KFM58478.1 - 3.3e-08 33.7 0.1 0.0063 16.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFM58478.1 - 7.6e-08 32.2 0.8 0.0025 17.8 0.1 2.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFM58478.1 - 0.00023 21.5 0.2 0.0029 17.9 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFM58478.1 - 0.0039 17.4 1.3 0.058 13.6 0.3 2.6 1 1 1 2 2 2 2 Dockerin type I domain DUF5580 PF17743.1 KFM58478.1 - 0.01 14.4 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF3911 PF13050.6 KFM58478.1 - 0.024 14.8 2.0 0.9 9.7 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3911) EF-hand_11 PF08976.11 KFM58478.1 - 0.039 14.8 0.0 0.095 13.6 0.0 1.6 1 1 1 2 2 2 0 EF-hand domain MotA_activ PF09114.10 KFM58478.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.7 1 1 1 2 2 2 0 Transcription factor MotA, activation domain DUF3427 PF11907.8 KFM58478.1 - 0.047 13.0 0.0 0.35 10.1 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3427) UPF0154 PF03672.13 KFM58478.1 - 0.051 13.6 0.2 18 5.5 0.0 2.7 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0154) IF3_N PF05198.16 KFM58478.1 - 0.088 13.1 0.1 3.1 8.1 0.1 2.3 1 1 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain DED PF01335.21 KFM58478.1 - 0.13 12.6 0.7 1.5 9.1 0.1 2.1 2 0 0 2 2 2 0 Death effector domain SUZ PF12752.7 KFM58480.1 - 4.1e-14 53.1 0.3 1.1e-13 51.8 0.1 1.9 1 1 0 1 1 1 1 SUZ domain SUZ-C PF12901.7 KFM58480.1 - 0.0017 18.3 0.4 0.004 17.1 0.4 1.7 1 0 0 1 1 1 1 SUZ-C motif GreA_GreB PF01272.19 KFM58480.1 - 0.12 12.2 0.1 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term Asp PF00026.23 KFM58481.1 - 1.6e-38 132.9 2.7 1.9e-38 132.6 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KFM58481.1 - 3.4e-09 36.7 0.0 5.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 KFM58481.1 - 1.6e-07 31.7 0.1 0.00038 20.7 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal zf-C4 PF00105.18 KFM58483.1 - 1.2e-29 102.6 16.1 2.6e-29 101.5 15.0 2.1 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFM58483.1 - 7e-16 58.4 0.4 2.3e-15 56.8 0.4 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor FAM176 PF14851.6 KFM58484.1 - 0.0054 16.4 0.1 0.0054 16.4 0.1 2.9 4 0 0 4 4 4 2 FAM176 family IBN_N PF03810.19 KFM58485.1 - 2.9e-11 43.1 0.0 1.5e-10 40.8 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFM58485.1 - 0.00034 20.7 3.2 0.00093 19.3 0.0 3.4 3 0 0 3 3 3 1 Exportin 1-like protein RTP1_C1 PF10363.9 KFM58485.1 - 0.0039 17.4 0.4 11 6.2 0.0 4.4 4 1 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 ACDC PF14733.6 KFM58485.1 - 0.26 11.6 1.9 0.63 10.4 0.4 2.5 2 0 0 2 2 2 0 AP2-coincident C-terminal POPLD PF08170.12 KFM58486.1 - 1.2e-24 86.5 0.2 5.2e-24 84.4 0.0 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain POP1 PF06978.11 KFM58487.1 - 3.7e-38 131.6 13.5 3.7e-24 85.9 4.6 2.0 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 GCV_T PF01571.21 KFM58487.1 - 0.014 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DEK_C PF08766.11 KFM58488.1 - 0.0036 17.2 0.5 0.0063 16.4 0.5 1.4 1 0 0 1 1 1 1 DEK C terminal domain DSPc PF00782.20 KFM58489.1 - 1.2e-34 119.0 0.0 2.2e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM58489.1 - 0.0088 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LptF_LptG PF03739.14 KFM58489.1 - 0.15 10.9 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG CAP_N PF01213.19 KFM58490.1 - 0.041 13.4 3.6 0.076 12.5 3.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KFM58490.1 - 5.5 7.0 11.3 1.3 9.1 6.4 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SUI1 PF01253.22 KFM58493.1 - 9.8e-20 70.9 0.0 1.7e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Metallophos PF00149.28 KFM58494.1 - 5.1e-15 56.5 0.3 6.8e-15 56.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM58494.1 - 3.9e-06 27.2 0.0 6e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CHCH PF06747.13 KFM58495.1 - 2.2e-08 34.0 8.9 2.8e-08 33.7 8.9 1.1 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 KFM58495.1 - 0.0023 18.0 10.0 0.0029 17.7 10.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) P_C PF06640.11 KFM58495.1 - 0.23 11.6 3.8 0.31 11.2 3.8 1.1 1 0 0 1 1 1 0 P protein C-terminus Cyclin_C_2 PF16899.5 KFM58496.1 - 1.5e-18 67.1 0.0 1e-17 64.4 0.0 2.4 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KFM58496.1 - 1.2e-12 47.7 0.6 9e-12 44.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KFM58496.1 - 0.028 14.5 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat MAM PF00629.23 KFM58497.1 - 5.1e-69 231.3 0.6 2.3e-28 99.1 0.1 3.2 3 0 0 3 3 3 3 MAM domain, meprin/A5/mu NUSAP PF16006.5 KFM58498.1 - 4.6e-17 62.7 36.1 7.5e-10 39.0 6.5 4.1 1 1 2 3 3 3 2 Nucleolar and spindle-associated protein Rho_N PF07498.12 KFM58498.1 - 0.00044 20.1 0.2 0.00096 19.0 0.2 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain GAS2 PF02187.17 KFM58499.1 - 1.4e-15 57.1 0.1 3.2e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFM58499.1 - 2.9e-12 46.7 0.2 5.4e-12 45.9 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Pkinase PF00069.25 KFM58500.1 - 9e-21 74.4 0.0 3.1e-13 49.7 0.0 2.5 1 1 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 KFM58500.1 - 1.3e-09 38.5 8.6 0.00025 21.8 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 KFM58500.1 - 9.9e-09 34.8 0.0 2.8e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 KFM58500.1 - 4.6e-06 26.8 0.1 1.7 9.0 0.0 5.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT PF02985.22 KFM58500.1 - 4.2e-05 23.5 4.6 0.083 13.2 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KFM58500.1 - 0.00043 20.6 0.2 0.0073 16.7 0.0 2.9 2 1 1 3 3 3 1 HEAT repeats IFRD PF05004.13 KFM58500.1 - 0.035 13.2 1.3 0.11 11.6 0.2 2.2 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) DUF2813 PF11398.8 KFM58500.1 - 0.21 10.8 2.6 0.2 10.9 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) HEAT_EZ PF13513.6 KFM58500.1 - 6.5 7.4 5.3 3.8 8.1 0.1 3.5 4 0 0 4 4 4 0 HEAT-like repeat DUF1308 PF07000.11 KFM58501.1 - 1.4e-64 217.0 0.3 2.8e-64 216.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KFM58501.1 - 2.5e-39 134.9 1.0 4.1e-39 134.2 1.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5614) SdpA PF17418.2 KFM58501.1 - 0.083 12.7 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Sporulation delaying protein SdpA Pro_isomerase PF00160.21 KFM58502.1 - 3.6e-45 154.1 0.3 4.1e-45 153.9 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BNR PF02012.20 KFM58503.1 - 1.9e-05 24.0 2.0 1.6 9.0 0.1 4.1 3 0 0 3 3 3 3 BNR/Asp-box repeat EGF_2 PF07974.13 KFM58503.1 - 0.0011 19.2 15.2 0.0011 19.2 15.2 2.4 3 0 0 3 3 3 1 EGF-like domain EGF PF00008.27 KFM58503.1 - 0.035 14.4 9.1 0.13 12.6 9.1 2.0 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 KFM58503.1 - 0.21 12.3 11.6 0.046 14.4 7.2 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 KFM58503.1 - 2 8.5 16.4 0.33 11.1 12.3 1.9 2 0 0 2 2 2 0 Tenascin EGF domain Reeler PF02014.16 KFM58506.1 - 8.3e-10 39.5 0.1 1.3e-09 38.9 0.1 1.3 1 0 0 1 1 1 1 Reeler domain TPR_MLP1_2 PF07926.12 KFM58507.1 - 1.5e-05 25.1 94.3 0.12 12.4 27.6 6.2 1 1 5 6 6 6 5 TPR/MLP1/MLP2-like protein GAS PF13851.6 KFM58507.1 - 3.8e-05 23.1 94.6 0.019 14.3 33.3 4.1 1 1 3 4 4 4 4 Growth-arrest specific micro-tubule binding JAKMIP_CC3 PF16034.5 KFM58507.1 - 0.0051 16.8 19.2 0.0051 16.8 19.2 4.5 1 1 4 5 5 4 2 JAKMIP CC3 domain HMMR_N PF15905.5 KFM58507.1 - 0.0069 15.9 28.7 0.0069 15.9 28.7 3.3 1 1 2 3 3 3 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KFM58507.1 - 0.0069 15.3 85.9 0.036 13.0 19.6 4.0 1 1 2 3 3 3 2 Spc7 kinetochore protein DUF4407 PF14362.6 KFM58507.1 - 0.068 12.5 59.8 0.77 9.1 11.5 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KFM58507.1 - 0.86 7.0 77.9 0.7 7.3 23.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Filament PF00038.21 KFM58507.1 - 1.9 8.0 84.5 5 6.6 17.5 5.1 1 1 4 5 5 5 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 KFM58507.1 - 5.5 7.0 88.8 0.44 10.6 18.3 4.9 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KFM58507.1 - 5.6 7.4 80.2 2.3 8.6 25.0 3.5 1 1 2 3 3 3 0 Fez1 DUF2353 PF09789.9 KFM58507.1 - 7.8 5.7 79.8 3.9 6.7 16.7 4.2 1 1 3 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) Leu_zip PF15294.6 KFM58507.1 - 9.9 5.6 77.2 0.082 12.4 27.7 3.6 1 1 3 4 4 4 0 Leucine zipper Sod_Cu PF00080.20 KFM58511.1 - 3.6e-37 127.7 4.6 3.6e-37 127.7 4.6 5.1 2 2 2 4 4 4 2 Copper/zinc superoxide dismutase (SODC) Prominin PF05478.11 KFM58511.1 - 0.076 11.0 1.8 0.11 10.5 1.8 1.1 1 0 0 1 1 1 0 Prominin Pkinase PF00069.25 KFM58512.1 - 8.3e-36 123.7 0.0 2.4e-35 122.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM58512.1 - 8.2e-34 117.0 0.0 4.6e-33 114.6 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM58512.1 - 6.3e-05 21.9 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM58512.1 - 0.00079 18.5 0.2 0.0018 17.3 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KFM58512.1 - 0.034 13.5 0.0 0.1 11.9 0.0 1.8 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFM58512.1 - 0.098 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF465 PF04325.13 KFM58512.1 - 0.2 11.7 3.5 0.96 9.5 3.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Casc1_N PF15927.5 KFM58512.1 - 1.2 8.8 4.1 0.65 9.7 0.2 2.4 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus NDUFA12 PF05071.16 KFM58513.1 - 2.6e-29 101.9 2.1 3.2e-29 101.6 2.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 IGFBP PF00219.18 KFM58514.1 - 0.0043 17.7 30.1 0.0077 16.9 30.1 1.4 1 0 0 1 1 1 1 Insulin-like growth factor binding protein DUF3144 PF11342.8 KFM58515.1 - 0.13 12.5 0.7 0.29 11.5 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) EIIBC-GUT_N PF03612.14 KFM58515.1 - 0.31 10.8 4.2 0.75 9.5 0.7 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Pannexin_like PF12534.8 KFM58515.1 - 1 8.4 9.9 0.1 11.7 4.7 1.8 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 CLN3 PF02487.17 KFM58515.1 - 5.8 5.8 4.9 1.4 7.9 1.7 1.5 2 0 0 2 2 2 0 CLN3 protein C2 PF00168.30 KFM58517.1 - 4.7e-26 91.1 0.0 7.7e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain Nodulin_late PF07127.11 KFM58518.1 - 0.0011 19.2 0.8 0.0015 18.9 0.8 1.2 1 0 0 1 1 1 1 Late nodulin protein DX PF01666.17 KFM58518.1 - 0.0044 17.4 2.4 0.0044 17.4 2.4 1.4 1 1 0 1 1 1 1 DX module Nodulin_late PF07127.11 KFM58519.1 - 0.012 15.9 1.5 0.012 15.9 1.5 2.0 2 0 0 2 2 2 0 Late nodulin protein AAA PF00004.29 KFM58520.1 - 9.9e-38 129.6 0.0 2.6e-37 128.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM58520.1 - 1.3e-23 82.5 0.0 2.7e-15 55.9 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 KFM58520.1 - 0.00017 21.6 0.0 0.0052 16.8 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFM58520.1 - 0.00053 19.3 0.0 0.0009 18.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KFM58520.1 - 0.00077 19.6 0.0 0.0079 16.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFM58520.1 - 0.0016 18.2 0.0 0.0052 16.5 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KFM58520.1 - 0.0062 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KFM58520.1 - 0.027 14.4 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KFM58520.1 - 0.033 14.6 0.0 7 7.0 0.0 3.0 2 1 0 3 3 3 0 AAA ATPase domain Vps4_C PF09336.10 KFM58520.1 - 0.054 13.5 0.1 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KFM58520.1 - 0.091 13.0 0.0 13 6.0 0.0 3.1 1 1 2 3 3 3 0 AAA domain AAA_14 PF13173.6 KFM58520.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM58521.1 - 4e-06 27.3 0.0 1.5e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 KFM58521.1 - 1.2e-05 24.5 0.0 2.5e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 PrkA AAA domain DUF815 PF05673.13 KFM58521.1 - 0.00021 20.5 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KFM58521.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFM58521.1 - 0.0061 17.1 1.9 0.25 11.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFM58521.1 - 0.015 15.2 0.1 0.043 13.7 0.1 1.7 1 1 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KFM58521.1 - 0.031 14.3 0.1 0.068 13.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KFM58521.1 - 0.033 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 KFM58521.1 - 0.038 14.4 0.1 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Molydop_binding PF01568.21 KFM58521.1 - 0.042 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain TniB PF05621.11 KFM58521.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 KFM58521.1 - 0.068 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain UTP25 PF06862.12 KFM58522.1 - 1e-157 525.7 4.3 1.5e-157 525.2 4.3 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 7tm_3 PF00003.22 KFM58524.1 - 1.3e-31 110.2 26.2 1.9e-31 109.6 26.1 1.3 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2407_C PF13373.6 KFM58524.1 - 0.24 11.6 0.1 0.47 10.6 0.1 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain WW_1 PF18507.1 KFM58526.1 - 3.8e-05 23.3 0.0 5 6.9 0.0 3.7 3 0 0 3 3 3 3 WW domain DUF3086 PF11285.8 KFM58527.1 - 0.027 13.6 1.0 0.11 11.5 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) BPTA PF17044.5 KFM58527.1 - 0.038 13.9 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 Borrelial persistence in ticks protein A C2 PF00168.30 KFM58530.1 - 3.2e-27 94.8 0.0 9.6e-16 57.9 0.0 2.7 2 1 0 2 2 2 2 C2 domain DUF4692 PF15763.5 KFM58530.1 - 0.017 15.6 0.4 0.67 10.4 0.1 2.3 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DOCK-C2 PF14429.6 KFM58530.1 - 0.041 13.7 0.7 8 6.2 0.1 2.4 1 1 1 2 2 2 0 C2 domain in Dock180 and Zizimin proteins PI3K_C2 PF00792.24 KFM58530.1 - 0.048 13.6 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 Shisa PF13908.6 KFM58530.1 - 2.4 8.3 4.3 1.1 9.5 1.4 1.9 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator CUB PF00431.20 KFM58531.1 - 3e-05 24.3 0.0 0.00024 21.4 0.0 2.2 2 0 0 2 2 2 1 CUB domain Ras PF00071.22 KFM58533.1 - 2.4e-34 118.3 0.0 2.8e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM58533.1 - 4.4e-30 104.3 0.0 6.2e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM58533.1 - 3.5e-09 36.4 0.0 4.5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM58533.1 - 4.7e-06 26.1 0.0 5.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM58533.1 - 9.1e-05 22.1 0.0 0.0026 17.3 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM58533.1 - 0.00051 20.1 0.0 0.0009 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFM58533.1 - 0.0043 16.5 0.0 0.0068 15.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KFM58533.1 - 0.096 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FMN_dh PF01070.18 KFM58534.1 - 5.4e-103 344.7 0.4 3.1e-102 342.2 0.4 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFM58534.1 - 1.6e-06 27.4 1.5 0.00015 20.9 0.6 2.7 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KFM58534.1 - 0.007 15.6 1.0 0.65 9.1 0.1 2.2 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 KFM58534.1 - 0.011 14.9 0.1 0.023 13.8 0.1 1.5 1 1 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.21 KFM58534.1 - 0.13 11.7 0.3 0.54 9.7 0.0 2.1 2 1 1 3 3 3 0 Histidine biosynthesis protein Med16 PF11635.8 KFM58538.1 - 3.6e-40 137.6 0.1 4.8e-40 137.2 0.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 16 SUFU_C PF12470.8 KFM58539.1 - 7.7e-70 235.1 0.0 9.9e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.13 KFM58539.1 - 3.8e-49 167.0 0.0 5.7e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) Peptidase_S8 PF00082.22 KFM58540.1 - 9.6e-05 21.8 0.0 0.00013 21.3 0.0 1.1 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 KFM58541.1 - 5.2e-28 98.2 1.8 7.5e-28 97.6 1.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFM58541.1 - 3.1e-27 94.4 0.0 6.5e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF3185 PF11381.8 KFM58542.1 - 0.076 13.0 0.0 0.089 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) 14-3-3 PF00244.20 KFM58543.1 - 1.1e-53 182.0 0.1 1.3e-53 181.8 0.1 1.1 1 0 0 1 1 1 1 14-3-3 protein FmiP_Thoc5 PF09766.9 KFM58544.1 - 4.3e-108 361.9 10.2 5.7e-108 361.5 10.2 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 RWD PF05773.22 KFM58544.1 - 0.042 14.1 0.1 0.042 14.1 0.1 2.3 2 1 0 2 2 2 0 RWD domain DUF1664 PF07889.12 KFM58544.1 - 0.45 10.6 2.7 4.2 7.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 KFM58544.1 - 0.97 9.3 7.6 2.5 8.0 0.4 2.9 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor BLOC1_2 PF10046.9 KFM58544.1 - 7.3 7.0 11.9 1.8 8.9 1.1 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BBS2_Mid PF14783.6 KFM58546.1 - 7.1e-07 29.2 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region Carn_acyltransf PF00755.20 KFM58547.1 - 3.4e-99 333.1 0.0 3.9e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.20 KFM58548.1 - 5.2e-54 183.9 2.0 6.1e-54 183.6 2.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 KFM58548.1 - 1.3e-23 82.7 0.5 2.6e-23 81.7 0.5 1.5 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus Ras PF00071.22 KFM58549.1 - 3.5e-26 91.7 0.0 4.2e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM58549.1 - 0.00014 22.0 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM58549.1 - 0.041 13.3 0.1 0.25 10.8 0.1 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family SRPRB PF09439.10 KFM58549.1 - 0.057 12.9 0.3 0.36 10.2 0.3 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit CAP PF00188.26 KFM58550.1 - 1.3e-20 74.5 0.4 1.3e-20 74.5 0.4 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family 7tm_1 PF00001.21 KFM58551.1 - 4.1e-24 85.3 16.4 5e-24 85.0 16.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gaa1 PF04114.14 KFM58551.1 - 0.07 12.1 7.1 0.0097 15.0 2.6 1.6 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component Col_cuticle_N PF01484.17 KFM58551.1 - 0.13 12.3 0.3 0.13 12.3 0.3 2.2 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF4711 PF15829.5 KFM58551.1 - 0.6 10.0 3.1 1.2 9.1 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) G-patch PF01585.23 KFM58554.1 - 3e-11 43.0 0.8 6.3e-11 42.0 0.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFM58554.1 - 5.5 7.2 6.4 0.84 9.8 0.2 3.1 2 0 0 2 2 2 0 G-patch domain Ets PF00178.22 KFM58557.1 - 2.9e-12 46.9 0.8 3.1e-12 46.8 0.8 1.0 1 0 0 1 1 1 1 Ets-domain KN17_SH3 PF18131.1 KFM58557.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 KN17 SH3-like C-terminal domain BTB PF00651.31 KFM58558.1 - 2.5e-25 88.9 2.2 4.2e-25 88.1 2.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM58558.1 - 9.2e-06 25.7 2.3 6.4e-05 23.0 0.2 3.0 4 0 0 4 4 4 1 BTB And C-terminal Kelch BTB PF00651.31 KFM58559.1 - 9.6e-24 83.8 2.2 1.6e-23 83.1 2.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM58559.1 - 0.018 15.1 0.3 0.86 9.7 0.0 2.4 2 0 0 2 2 2 0 BTB And C-terminal Kelch Ldl_recept_a PF00057.18 KFM58562.1 - 0.0013 18.9 1.1 0.0034 17.6 1.1 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFM58563.1 - 6.9e-28 97.2 0.0 5e-10 39.7 0.0 4.2 3 1 0 3 3 3 3 CUB domain 7tm_1 PF00001.21 KFM58564.1 - 3.1e-05 23.4 3.2 3.6e-05 23.2 1.4 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Sulfotransfer_1 PF00685.27 KFM58565.1 - 1.8e-52 178.5 0.2 2.2e-52 178.2 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM58565.1 - 1.8e-09 38.3 0.0 3.2e-06 27.7 0.1 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM58566.1 - 1.3e-53 182.2 0.2 1.7e-53 181.9 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM58566.1 - 4e-10 40.4 0.0 6.1e-07 30.1 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Borrelia_lipo_1 PF05714.11 KFM58566.1 - 0.039 13.7 0.9 0.058 13.2 0.9 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein MAM PF00629.23 KFM58567.1 - 1.6e-06 28.1 1.4 6e-06 26.3 1.4 1.8 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu DUF4969 PF16339.5 KFM58567.1 - 0.021 15.2 0.3 0.085 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) Form_Nir_trans PF01226.17 KFM58567.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Formate/nitrite transporter MAM PF00629.23 KFM58568.1 - 7.9e-13 48.6 0.5 2.1e-12 47.2 0.5 1.6 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KFM58569.1 - 8e-12 45.4 0.9 2.4e-11 43.8 0.9 1.7 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu Sif PF06767.11 KFM58569.1 - 0.15 11.1 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Sif protein MAM PF00629.23 KFM58570.1 - 5.7e-16 58.8 0.3 1.4e-15 57.6 0.3 1.6 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KFM58571.1 - 2e-10 40.8 0.0 4.4e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu LPD18 PF18832.1 KFM58571.1 - 0.063 13.3 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 Astacin PF01400.24 KFM58572.1 - 5.6e-60 202.2 0.0 8.5e-60 201.7 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 KFM58572.1 - 1e-16 61.3 0.0 1.9e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Peptidase_M10 PF00413.24 KFM58572.1 - 0.082 12.7 6.9 0.22 11.4 2.2 3.0 3 1 0 4 4 4 0 Matrixin Peptidase_A22B PF04258.13 KFM58573.1 - 1.9e-88 296.7 10.5 2.3e-88 296.4 10.5 1.0 1 0 0 1 1 1 1 Signal peptide peptidase Presenilin PF01080.17 KFM58573.1 - 0.0024 16.7 1.8 0.0024 16.7 1.8 1.9 2 0 0 2 2 2 1 Presenilin DUF1700 PF08006.11 KFM58573.1 - 9.1 5.8 18.6 0.055 13.0 1.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) Ion_trans PF00520.31 KFM58574.1 - 6.2e-21 74.7 9.8 2.3e-12 46.7 2.0 2.0 2 0 0 2 2 2 2 Ion transport protein Lactate_perm PF02652.14 KFM58574.1 - 0.051 12.3 1.8 0.067 11.9 1.8 1.1 1 0 0 1 1 1 0 L-lactate permease DUF2417 PF10329.9 KFM58574.1 - 0.06 12.8 2.8 2.6 7.4 0.2 2.1 2 0 0 2 2 2 0 Region of unknown function (DUF2417) UPF0542 PF15086.6 KFM58574.1 - 0.33 10.9 5.4 2.1 8.3 0.1 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0542 Ion_trans PF00520.31 KFM58575.1 - 1.8e-44 151.8 10.8 2e-44 151.6 10.8 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM58575.1 - 0.0013 17.5 5.7 0.0015 17.3 4.2 1.8 1 1 0 2 2 2 1 Polycystin cation channel Ca_chan_IQ PF08763.11 KFM58576.1 - 1.8e-31 108.1 0.1 3.2e-31 107.4 0.1 1.4 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KFM58576.1 - 1.5e-14 53.5 1.2 2.9e-14 52.6 1.2 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF3894 PF13033.6 KFM58577.1 - 0.0072 16.4 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3894) ANAPC2 PF08672.11 KFM58577.1 - 0.028 14.9 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 IFT46_B_C PF12317.8 KFM58578.1 - 3.5e-102 340.6 0.4 4.7e-102 340.2 0.4 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal AFP_2 PF18815.1 KFM58578.1 - 0.099 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial antifreeze protein repeat Protamine_P2 PF00841.19 KFM58578.1 - 0.14 12.6 2.6 0.29 11.6 2.6 1.4 1 0 0 1 1 1 0 Sperm histone P2 DNA_pol_phi PF04931.13 KFM58578.1 - 0.83 7.7 5.5 1.2 7.2 5.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KFM58578.1 - 1.6 8.0 8.1 2.1 7.6 8.1 1.2 1 0 0 1 1 1 0 BUD22 TFIIE-A_C PF11521.8 KFM58578.1 - 6 7.3 13.3 0.11 12.8 2.9 2.8 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha 2-oxoacid_dh PF00198.23 KFM58579.1 - 2.8e-80 269.1 0.0 4.2e-80 268.5 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFM58579.1 - 1e-18 66.9 0.1 2.2e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFM58579.1 - 8.8e-15 54.8 0.5 2.2e-14 53.5 0.1 1.9 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFM58579.1 - 0.021 14.6 0.7 10 6.1 0.0 3.0 1 1 1 2 2 2 0 Biotin-lipoyl like GATA PF00320.27 KFM58581.1 - 2.5e-12 46.2 17.4 3.4e-09 36.1 6.8 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFM58581.1 - 0.013 15.0 10.7 0.029 13.9 3.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.6 KFM58581.1 - 3.4 7.7 12.6 4.7 7.2 3.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-CHY PF05495.12 KFM58581.1 - 7 7.2 13.5 2.2 8.8 8.2 2.2 1 1 1 2 2 2 0 CHY zinc finger Prok-RING_2 PF14445.6 KFM58581.1 - 9.2 6.5 11.4 6.7 7.0 2.4 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 LRR_6 PF13516.6 KFM58582.1 - 8.7e-05 22.3 5.1 0.34 11.1 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 KFM58582.1 - 0.92 10.0 27.5 2.6 8.6 0.0 7.3 5 4 1 6 6 6 0 Leucine Rich repeats (2 copies) Sec2p PF06428.11 KFM58584.1 - 1.5e-09 37.7 6.9 1.5e-09 37.7 6.9 3.4 2 2 1 3 3 3 1 GDP/GTP exchange factor Sec2p TMF_TATA_bd PF12325.8 KFM58584.1 - 0.0013 18.9 12.0 0.0013 18.9 12.0 2.5 2 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding CEP63 PF17045.5 KFM58584.1 - 0.014 15.3 17.4 0.037 13.9 17.3 1.9 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa Arc_PepC PF06819.11 KFM58584.1 - 0.042 14.0 2.2 0.14 12.2 2.2 1.9 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Lebercilin PF15619.6 KFM58584.1 - 1.3 8.6 18.2 0.34 10.6 2.2 3.5 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Cep57_CLD_2 PF14197.6 KFM58584.1 - 1.6 8.8 12.4 1.9 8.7 2.3 3.1 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 HR1 PF02185.16 KFM58584.1 - 1.8 8.7 18.3 0.17 12.1 3.6 3.6 3 0 0 3 3 3 0 Hr1 repeat CENP-C_C PF11699.8 KFM58586.1 - 1.1e-14 54.4 0.1 3.1e-14 52.9 0.1 1.9 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KFM58586.1 - 3.4e-05 23.5 0.0 7.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Cupin domain LHH PF14411.6 KFM58586.1 - 9.7 6.4 8.7 4.7 7.5 1.2 3.3 2 1 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Dynamin_N PF00350.23 KFM58587.1 - 2.6e-40 138.2 3.1 2.3e-39 135.1 0.1 2.2 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 KFM58587.1 - 2.2e-05 24.0 0.1 0.0031 17.1 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KFM58587.1 - 0.00023 21.2 0.4 0.00091 19.3 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF1593 PF07632.11 KFM58587.1 - 0.00025 20.6 0.8 0.0019 17.7 0.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1593) Roc PF08477.13 KFM58587.1 - 0.00089 19.5 0.0 0.38 11.0 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM58587.1 - 0.026 14.1 0.0 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Ras family SlyX PF04102.12 KFM58587.1 - 0.035 14.7 1.0 0.48 11.1 1.7 2.5 2 0 0 2 2 2 0 SlyX Med21 PF11221.8 KFM58587.1 - 0.041 14.1 4.3 0.12 12.6 4.3 1.7 1 0 0 1 1 1 0 Subunit 21 of Mediator complex AAA_16 PF13191.6 KFM58587.1 - 0.044 14.2 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 KFM58587.1 - 0.067 12.9 7.0 0.36 10.5 0.0 2.5 1 1 0 2 2 2 0 AAA ATPase domain Stevor PF17410.2 KFM58587.1 - 0.068 12.7 4.6 0.13 11.8 4.6 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame AAA_23 PF13476.6 KFM58587.1 - 5.5 7.4 0.0 5.5 7.4 0.0 2.7 2 1 0 2 2 1 0 AAA domain AA_permease PF00324.21 KFM58589.1 - 4.1e-52 177.3 23.1 5.4e-52 177.0 23.1 1.2 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFM58589.1 - 1.4e-21 77.1 0.1 2.4e-10 40.0 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 CoA_binding_3 PF13727.6 KFM58589.1 - 0.11 12.5 1.9 0.33 10.9 1.9 1.8 1 0 0 1 1 1 0 CoA-binding domain YbhQ PF11076.8 KFM58589.1 - 5.3 7.1 8.7 0.29 11.2 0.5 2.6 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ AA_permease PF00324.21 KFM58590.1 - 5e-17 61.7 15.2 6.3e-17 61.3 15.2 1.1 1 0 0 1 1 1 1 Amino acid permease Ig_3 PF13927.6 KFM58592.1 - 2.1e-13 50.6 0.0 2.4e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM58592.1 - 9e-12 44.9 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM58592.1 - 2.2e-11 43.8 0.0 2.3e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM58592.1 - 1.6e-09 37.9 0.0 1.9e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM58592.1 - 0.00013 22.1 0.0 0.067 13.4 0.0 2.0 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM58592.1 - 0.0039 17.5 0.0 0.0065 16.8 0.0 1.3 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM58592.1 - 0.044 14.1 0.0 0.18 12.1 0.0 1.8 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFM58592.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 1 0 1 1 1 0 C17orf99 Ig domain C2-set_2 PF08205.12 KFM58592.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Sugar_tr PF00083.24 KFM58595.1 - 1.2e-89 301.3 7.2 1.3e-89 301.1 7.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM58595.1 - 1.9e-16 60.0 10.7 2.5e-16 59.6 10.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM58596.1 - 1.2e-06 27.7 0.9 1.5e-06 27.4 0.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1465 PF07323.12 KFM58597.1 - 0.0024 17.7 7.7 0.0024 17.7 7.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1465) Wzy_C PF04932.15 KFM58597.1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 O-Antigen ligase PI_PP_I PF18363.1 KFM58597.1 - 0.25 11.5 5.4 0.99 9.6 5.0 2.3 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain DUF4164 PF13747.6 KFM58597.1 - 0.54 10.6 15.5 0.64 10.3 1.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DivIC PF04977.15 KFM58597.1 - 9.5 6.1 29.1 0.14 11.9 4.6 4.3 3 1 0 4 4 4 0 Septum formation initiator SLED PF12140.8 KFM58598.1 - 2.1e-19 70.0 0.3 4.8e-19 68.9 0.3 1.6 1 0 0 1 1 1 1 SLED domain LacI PF00356.21 KFM58598.1 - 0.15 11.8 0.3 0.58 10.0 0.2 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Mannosyl_trans2 PF04188.13 KFM58599.1 - 1.6e-13 50.8 6.1 1.7e-13 50.7 6.1 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) PAN_1 PF00024.26 KFM58602.1 - 5.1e-13 48.8 2.1 8e-13 48.2 2.1 1.3 1 0 0 1 1 1 1 PAN domain DDE_3 PF13358.6 KFM58603.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 DDE superfamily endonuclease DUF2439 PF10382.9 KFM58604.1 - 0.0024 18.2 0.5 0.0024 18.2 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) KapB PF08810.10 KFM58604.1 - 0.0076 16.4 0.8 0.046 13.9 0.2 2.1 2 0 0 2 2 2 1 Kinase associated protein B SNF2_N PF00176.23 KFM58605.1 - 5.6e-37 127.3 1.0 8.8e-37 126.6 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM58605.1 - 8e-16 58.4 0.2 3.7e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFM58605.1 - 0.00017 20.9 0.2 0.00075 18.8 0.2 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KFM58605.1 - 0.00041 20.4 0.0 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFM58605.1 - 0.02 14.6 0.1 0.073 12.7 0.0 1.9 3 0 0 3 3 3 0 SWI2/SNF2 ATPase Asp_Glu_race PF01177.22 KFM58605.1 - 0.03 14.2 0.0 24 4.7 0.0 3.1 3 0 0 3 3 3 0 Asp/Glu/Hydantoin racemase E1-E2_ATPase PF00122.20 KFM58607.1 - 1.2e-54 184.6 5.6 1.8e-52 177.5 0.8 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFM58607.1 - 1.6e-42 145.3 3.3 1.6e-42 145.3 3.3 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFM58607.1 - 2.9e-22 80.0 0.0 1.7e-21 77.5 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFM58607.1 - 3.6e-19 68.2 1.8 8e-19 67.1 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFM58607.1 - 1.6e-18 66.5 0.1 3.4e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFM58607.1 - 7.5e-07 29.1 1.6 1.2e-05 25.2 0.8 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM58607.1 - 1.3e-05 25.7 0.0 5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PIF1 PF05970.14 KFM58608.1 - 1.1e-11 44.6 0.0 1.2e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase CAF1 PF04857.20 KFM58611.1 - 4.1e-41 141.2 3.0 5.1e-41 140.9 3.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease TIMP PF00965.17 KFM58611.1 - 0.0088 15.9 1.1 0.057 13.2 0.2 2.1 1 1 1 2 2 2 1 Tissue inhibitor of metalloproteinase CAF1 PF04857.20 KFM58612.1 - 6.4e-11 42.0 0.0 6.8e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease COesterase PF00135.28 KFM58613.1 - 6e-26 91.4 0.0 6.8e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family TcpS PF17456.2 KFM58616.1 - 0.094 12.8 2.0 0.16 12.0 2.0 1.5 1 1 0 1 1 1 0 Toxin-coregulated pilus protein S Rtf2 PF04641.12 KFM58618.1 - 0.013 14.9 0.3 0.013 14.9 0.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF5301 PF17225.3 KFM58618.1 - 0.21 12.0 2.8 0.25 11.8 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) Pkinase PF00069.25 KFM58619.1 - 8e-41 140.1 0.0 1.1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM58619.1 - 1.3e-29 103.3 0.0 1.6e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM58619.1 - 2.7e-06 26.9 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM58619.1 - 0.00027 20.4 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM58619.1 - 0.072 13.0 0.0 1 9.2 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DDE_3 PF13358.6 KFM58622.1 - 1.6e-06 28.0 0.0 2.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease MRP-S27 PF10037.9 KFM58623.1 - 0.00032 19.7 6.1 0.00032 19.7 6.1 1.6 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S27 DUF1947 PF09183.10 KFM58623.1 - 0.011 16.1 3.0 0.017 15.4 2.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1947) Tox-REase-7 PF15649.6 KFM58623.1 - 8.5 6.8 8.0 19 5.6 0.7 2.6 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 7 3Beta_HSD PF01073.19 KFM58624.1 - 8.8e-19 67.6 0.0 1.1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFM58624.1 - 1.4e-17 64.0 0.0 2.9e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFM58624.1 - 6e-12 45.8 0.0 8.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFM58624.1 - 6.5e-12 45.2 0.1 4e-11 42.6 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KFM58624.1 - 6.8e-08 32.3 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFM58624.1 - 2.2e-06 27.4 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KFM58624.1 - 0.0021 18.0 0.0 0.029 14.3 0.0 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KFM58624.1 - 0.029 13.8 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KFM58624.1 - 0.034 13.2 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain G-gamma PF00631.22 KFM58625.1 - 1.5e-14 53.7 0.1 1.6e-14 53.6 0.1 1.0 1 0 0 1 1 1 1 GGL domain Ank PF00023.30 KFM58627.1 - 1.7e-16 59.9 3.3 1.7e-05 25.1 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KFM58627.1 - 1.9e-16 60.4 0.2 3.5e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM58627.1 - 8.3e-15 55.0 0.9 0.00015 22.3 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM58627.1 - 1.8e-11 44.0 0.6 0.00019 21.7 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM58627.1 - 1.1e-10 40.8 0.6 0.0014 19.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat UPF0183 PF03676.14 KFM58628.1 - 9.9e-156 518.9 1.9 1.1e-155 518.8 1.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) SmpA_OmlA PF04355.13 KFM58628.1 - 0.017 14.9 0.0 0.095 12.5 0.0 2.2 2 0 0 2 2 2 0 SmpA / OmlA family CAP_assoc_N PF14504.6 KFM58628.1 - 0.076 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 CAP-associated N-terminal DUF3455 PF11937.8 KFM58629.1 - 0.054 13.9 0.0 0.062 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Sec23_helical PF04815.15 KFM58631.1 - 3.3e-27 94.3 0.2 7.7e-27 93.1 0.1 1.7 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFM58631.1 - 1.6e-19 70.4 0.0 3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KFM58631.1 - 5.9e-07 29.3 0.0 3.7e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KFM58632.1 - 3e-12 46.4 7.9 6.8e-12 45.2 7.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DDE_3 PF13358.6 KFM58633.1 - 0.0001 22.1 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1804 PF08822.11 KFM58635.1 - 0.0045 17.0 0.3 0.0073 16.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) Clusterin PF01093.17 KFM58636.1 - 0.011 14.8 0.3 0.013 14.6 0.3 1.0 1 0 0 1 1 1 0 Clusterin TPR_MLP1_2 PF07926.12 KFM58636.1 - 0.036 14.1 0.9 0.043 13.9 0.9 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Myosin_head PF00063.21 KFM58637.1 - 2.3e-44 151.7 0.0 2.8e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 KFM58637.1 - 0.00028 21.3 0.0 0.00037 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KFM58637.1 - 0.0057 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KFM58637.1 - 0.014 15.7 0.1 0.039 14.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain CNTF PF01110.17 KFM58637.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Ciliary neurotrophic factor Myosin_head PF00063.21 KFM58638.1 - 6.2e-06 24.7 0.0 7.5e-06 24.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Chlorosome_CsmC PF11098.8 KFM58638.1 - 0.0014 18.7 1.8 0.0017 18.3 1.8 1.3 1 1 0 1 1 1 1 Chlorosome envelope protein C HEPN_Toprim_N PF18871.1 KFM58638.1 - 0.18 11.7 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Myosin_head PF00063.21 KFM58639.1 - 7.3e-06 24.5 0.0 7.7e-06 24.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_head PF00063.21 KFM58640.1 - 1.5e-14 53.2 0.0 1.6e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFM58641.1 - 1.6e-05 24.3 0.7 1.6e-05 24.3 0.7 2.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif NUFIP1 PF10453.9 KFM58641.1 - 0.29 11.0 1.9 0.75 9.7 1.9 1.7 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) PIF1 PF05970.14 KFM58643.1 - 7.8e-06 25.3 0.6 1e-05 24.9 0.6 1.2 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 KFM58643.1 - 0.00012 20.2 0.0 0.00015 19.8 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KFM58643.1 - 0.0026 17.6 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain CTU2 PF10288.9 KFM58644.1 - 3e-15 56.4 1.1 3e-15 56.4 1.1 1.9 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 KFM58644.1 - 0.00021 21.1 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 PP-loop family DUF1284 PF06935.11 KFM58644.1 - 0.026 14.9 3.5 1.4 9.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) DAN PF03045.15 KFM58645.1 - 3.2e-33 114.1 3.4 5.6e-33 113.3 3.4 1.4 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFM58645.1 - 0.00013 22.2 3.9 0.00022 21.5 3.9 1.3 1 0 0 1 1 1 1 Cystine-knot domain Drf_FH1 PF06346.12 KFM58647.1 - 0.00024 20.9 91.0 0.00024 20.9 91.0 2.2 1 1 1 2 2 2 1 Formin Homology Region 1 TRAF_BIRC3_bd PF16673.5 KFM58648.1 - 0.053 13.3 0.3 0.068 13.0 0.3 1.2 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain DEP PF00610.21 KFM58649.1 - 0.05 13.7 0.0 0.08 13.0 0.0 1.5 1 1 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CRAL_TRIO PF00650.20 KFM58652.1 - 1e-12 48.1 0.1 2.5e-11 43.5 0.0 2.6 2 1 0 2 2 2 1 CRAL/TRIO domain W2 PF02020.18 KFM58652.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon CRAL_TRIO_N PF03765.15 KFM58652.1 - 0.087 13.0 0.2 0.2 11.9 0.2 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain DDE_3 PF13358.6 KFM58653.1 - 4.9e-15 55.5 0.0 1.7e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58653.1 - 1.4e-07 31.7 6.2 1.4e-07 31.7 6.2 1.8 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM58653.1 - 2.6e-05 24.8 5.3 0.0001 22.8 2.2 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM58653.1 - 0.00012 21.9 0.1 0.00035 20.4 0.1 1.8 1 0 0 1 1 1 1 Tc3 transposase HTH_38 PF13936.6 KFM58653.1 - 0.013 15.2 4.9 0.32 10.8 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain SpoIIID PF12116.8 KFM58653.1 - 0.017 15.2 0.6 0.035 14.2 0.6 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D DUF2774 PF11242.8 KFM58653.1 - 0.085 13.1 0.3 7.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.12 KFM58653.1 - 0.26 11.0 1.9 1.4 8.6 0.3 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 Tetraspanin PF00335.20 KFM58654.1 - 7e-51 173.1 12.7 7.8e-51 173.0 12.7 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KFM58654.1 - 0.51 10.0 2.8 0.68 9.6 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) QVR PF17064.5 KFM58655.1 - 3.8e-17 62.3 3.7 4.7e-17 62.0 3.7 1.1 1 0 0 1 1 1 1 Sleepless protein Activin_recp PF01064.23 KFM58655.1 - 0.077 14.1 4.2 0.12 13.5 4.3 1.3 1 1 0 1 1 1 0 Activin types I and II receptor domain CDT1 PF08839.11 KFM58657.1 - 2.3e-52 177.8 1.1 2.3e-52 177.8 1.1 2.9 3 1 0 3 3 3 1 DNA replication factor CDT1 like CDT1_C PF16679.5 KFM58657.1 - 1.4e-24 86.3 0.4 1.5e-22 79.8 0.1 3.2 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain SRA PF18491.1 KFM58657.1 - 1 9.5 5.6 1.6 8.8 0.0 3.1 3 0 0 3 3 3 0 SET and RING associated domain HNF_C PF09354.10 KFM58658.1 - 4.9e-08 33.9 6.1 2.5e-07 31.6 5.3 2.0 2 0 0 2 2 2 1 HNF3 C-terminal domain Scs3p PF10261.9 KFM58659.1 - 2.2e-24 86.3 21.4 2.7e-17 63.1 0.3 2.6 2 1 1 3 3 3 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 KFM58659.1 - 0.00043 20.1 0.4 0.00043 20.1 0.4 2.4 2 1 0 3 3 3 1 PAP2 superfamily Voltage_CLC PF00654.20 KFM58659.1 - 0.0045 16.3 2.5 0.006 15.9 2.5 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel BtpA PF03437.15 KFM58660.1 - 3.3e-54 184.0 1.5 3.8e-54 183.8 1.5 1.0 1 0 0 1 1 1 1 BtpA family DOR PF14839.6 KFM58661.1 - 4.2e-28 99.0 6.5 5.6e-28 98.6 6.5 1.2 1 0 0 1 1 1 1 DOR family Bacteriocin_IIc PF10439.9 KFM58662.1 - 4 7.6 12.6 7.9 6.7 12.6 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DAO PF01266.24 KFM58663.1 - 1.8e-36 126.5 0.0 2.1e-36 126.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM58663.1 - 0.12 11.6 0.0 0.41 9.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KFM58663.1 - 0.16 11.6 0.0 0.66 9.5 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Darcynin PF17074.5 KFM58663.1 - 0.18 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Darcynin, domain of unknown function MDM1 PF15501.6 KFM58663.1 - 0.29 10.3 0.0 0.38 9.8 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 HTH_9 PF08221.11 KFM58664.1 - 3.8e-21 74.9 1.8 6.1e-16 58.3 0.4 4.4 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 KFM58664.1 - 2.2e-19 70.2 1.7 5.1e-18 65.8 0.1 3.3 3 1 0 3 3 3 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 KFM58664.1 - 0.062 13.2 2.0 0.49 10.3 0.1 3.4 2 1 1 3 3 3 0 TFIIE alpha subunit PID PF00640.23 KFM58666.1 - 0.00011 22.3 0.2 0.00011 22.3 0.2 1.9 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFM58666.1 - 0.0025 17.9 0.6 0.006 16.7 0.1 1.9 2 0 0 2 2 2 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFM58666.1 - 0.057 13.3 0.1 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) efb-c PF12199.8 KFM58666.1 - 0.07 13.2 0.4 0.3 11.2 0.1 2.1 3 0 0 3 3 3 0 Extracellular fibrinogen binding protein C terminal PID PF00640.23 KFM58667.1 - 0.016 15.3 0.2 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) AhpC-TSA PF00578.21 KFM58668.1 - 4.9e-39 133.1 0.0 6.4e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM58668.1 - 4.3e-17 62.2 0.0 5.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFM58668.1 - 8e-17 60.8 0.1 1.4e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MACPF PF01823.19 KFM58670.1 - 0.006 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 MAC/Perforin domain TCTP PF00838.17 KFM58670.1 - 0.008 16.5 1.3 0.6 10.4 0.2 2.4 2 0 0 2 2 2 2 Translationally controlled tumour protein AMP-binding_C_2 PF14535.6 KFM58670.1 - 0.082 13.2 0.0 0.55 10.6 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF659 PF04937.15 KFM58672.1 - 5.3e-06 26.4 0.3 8.6e-06 25.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM58672.1 - 0.00023 20.9 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) FA_desaturase PF00487.24 KFM58673.1 - 3.3e-11 43.5 18.3 3.3e-11 43.5 18.3 1.8 1 1 1 2 2 2 2 Fatty acid desaturase FA_desaturase PF00487.24 KFM58674.1 - 1.7e-14 54.3 18.9 1.7e-14 54.3 18.9 2.0 1 1 1 2 2 2 1 Fatty acid desaturase MFS_1 PF07690.16 KFM58674.1 - 0.0016 17.5 0.3 0.082 11.8 0.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Tombus_P33 PF08500.10 KFM58674.1 - 0.081 12.9 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Tombusvirus p33 Glyco_hydro_38N PF01074.22 KFM58675.1 - 1.4e-93 313.4 4.4 2.3e-93 312.7 4.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 KFM58675.1 - 1.6e-24 85.9 0.2 4e-24 84.6 0.2 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Polyketide_cyc2 PF10604.9 KFM58677.1 - 0.0001 22.6 0.0 0.00013 22.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KFM58677.1 - 0.074 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein FGFR3_TM PF18123.1 KFM58677.1 - 0.085 12.4 2.8 0.14 11.7 2.8 1.4 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain GST_N_4 PF17172.4 KFM58678.1 - 2.5e-25 89.1 0.2 9.7e-25 87.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFM58678.1 - 1.2e-20 73.0 0.1 2.4e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFM58678.1 - 1.3e-09 38.4 0.0 3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KFM58678.1 - 4.5e-08 33.0 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM58678.1 - 0.00026 21.3 0.0 0.0011 19.3 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFM58678.1 - 0.11 12.8 0.1 0.81 10.1 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFM58678.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tnp_22_trimer PF17489.2 KFM58680.1 - 0.025 14.6 0.2 1.3 9.1 0.0 2.8 2 0 0 2 2 2 0 L1 transposable element trimerization domain DUF1667 PF07892.11 KFM58680.1 - 0.031 14.3 0.4 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1667) Rad51 PF08423.11 KFM58681.1 - 9.3e-10 38.2 0.0 9.7e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KFM58681.1 - 8.5e-05 22.0 0.3 0.00012 21.5 0.3 1.2 1 0 0 1 1 1 1 KaiC DNA_pol_lambd_f PF10391.9 KFM58681.1 - 0.037 13.9 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda RecA PF00154.21 KFM58681.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Rad51 PF08423.11 KFM58682.1 - 1e-12 47.9 0.0 1.1e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Rad51 DHC_N1 PF08385.12 KFM58683.1 - 3e-08 32.8 0.4 5.5e-08 31.9 0.4 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 TPR_1 PF00515.28 KFM58684.1 - 6.5e-22 76.4 7.3 1.6e-07 30.8 0.2 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM58684.1 - 1.8e-14 52.6 9.3 0.00011 22.0 0.3 4.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM58684.1 - 2.1e-14 52.9 2.2 7.7e-05 22.3 0.2 3.6 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 KFM58684.1 - 5e-12 45.0 10.1 2.5e-05 24.1 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM58684.1 - 1.3e-07 31.8 6.8 0.0034 17.7 3.1 3.6 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM58684.1 - 1.8e-05 25.2 1.4 0.13 13.1 1.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM58684.1 - 0.00014 22.3 1.3 0.05 14.3 0.2 3.3 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM58684.1 - 0.00024 20.9 8.6 0.19 11.8 0.9 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM58684.1 - 0.00033 20.7 3.2 0.00045 20.3 2.1 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM58684.1 - 0.00034 20.8 7.8 0.057 13.8 0.3 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFM58684.1 - 0.0014 17.9 3.8 0.01 15.0 0.5 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM58684.1 - 0.02 15.5 0.2 10 6.9 0.6 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM58684.1 - 0.23 12.0 9.5 0.34 11.4 3.5 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM58684.1 - 1.2 9.1 9.1 1.9 8.5 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANF_receptor PF01094.28 KFM58685.1 - 8.7e-44 150.1 0.0 3.9e-39 134.8 0.0 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region 7tm_3 PF00003.22 KFM58685.1 - 3.5e-35 121.8 22.5 5.8e-35 121.1 22.4 1.4 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR FDC-SP PF15215.6 KFM58685.1 - 0.037 14.6 1.1 0.1 13.2 1.1 1.7 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide DUF1345 PF07077.11 KFM58685.1 - 0.84 9.3 6.5 2.3 7.9 6.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1345) ANF_receptor PF01094.28 KFM58686.1 - 2.7e-73 247.1 0.2 5.9e-30 104.6 0.0 3.2 3 0 0 3 3 3 3 Receptor family ligand binding region Ion_trans PF00520.31 KFM58687.1 - 4.4e-22 78.5 11.6 6.6e-22 77.9 11.6 1.2 1 0 0 1 1 1 1 Ion transport protein KCNQ_channel PF03520.14 KFM58687.1 - 1.6e-21 77.0 0.3 1.6e-21 77.0 0.3 1.8 3 0 0 3 3 3 1 KCNQ voltage-gated potassium channel Ion_trans_2 PF07885.16 KFM58687.1 - 1.8e-09 37.4 7.8 1.8e-09 37.4 7.8 2.9 3 1 1 4 4 4 1 Ion channel Lig_chan PF00060.26 KFM58687.1 - 1.7 8.5 7.7 0.43 10.4 1.9 2.5 2 1 0 2 2 2 0 Ligand-gated ion channel DUF420 PF04238.12 KFM58687.1 - 8.4 6.7 9.3 2.4 8.5 1.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF420) Cullin PF00888.22 KFM58690.1 - 4.8e-09 35.4 0.8 6.7e-09 34.9 0.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin PF00888.22 KFM58691.1 - 8.1e-190 632.5 11.5 1.1e-189 632.1 11.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFM58691.1 - 1.6e-24 85.7 0.5 5.9e-24 83.9 0.5 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3179 PF11376.8 KFM58694.1 - 0.18 11.2 1.6 9 5.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3179) PWI PF01480.17 KFM58695.1 - 0.013 15.8 0.4 0.015 15.6 0.4 1.2 1 0 0 1 1 1 0 PWI domain DUF1326 PF07040.11 KFM58697.1 - 0.11 12.6 2.5 0.12 12.4 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) ArfGap PF01412.18 KFM58698.1 - 1e-38 132.0 0.0 4.2e-38 130.0 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ras PF00071.22 KFM58698.1 - 3.2e-17 62.6 0.0 5.9e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Ras family PH PF00169.29 KFM58698.1 - 1.8e-08 34.8 4.8 0.00044 20.7 0.1 3.3 3 0 0 3 3 3 2 PH domain Ank_4 PF13637.6 KFM58698.1 - 7.8e-07 29.5 0.5 0.001 19.6 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM58698.1 - 1.3e-06 28.5 0.2 3.3e-06 27.3 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM58698.1 - 4.3e-06 27.2 0.0 9.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM58698.1 - 4.3e-06 26.9 1.1 0.00069 20.0 0.4 2.8 2 0 0 2 2 2 1 Ankyrin repeat PH_11 PF15413.6 KFM58698.1 - 0.0003 21.2 0.2 0.93 9.9 0.1 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 KFM58698.1 - 0.0034 17.6 0.1 0.0086 16.4 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFM58698.1 - 0.049 13.9 0.7 2.9 8.2 0.2 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain Roc PF08477.13 KFM58698.1 - 0.077 13.2 0.1 0.39 11.0 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ank_3 PF13606.6 KFM58698.1 - 0.11 13.1 0.1 0.35 11.6 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat NB-ARC PF00931.22 KFM58699.1 - 1.7e-25 89.7 0.7 6.7e-25 87.7 0.7 1.8 1 1 0 1 1 1 1 NB-ARC domain CARD PF00619.21 KFM58699.1 - 9.6e-08 32.0 0.0 6.4e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Caspase recruitment domain ATPase_2 PF01637.18 KFM58699.1 - 0.061 13.2 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea APAF1_C PF17908.1 KFM58700.1 - 0.0016 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 APAF-1 helical domain DUF4215 PF13948.6 KFM58700.1 - 0.013 15.9 0.5 0.024 15.1 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4215) WD40 PF00400.32 KFM58701.1 - 1e-17 64.1 13.5 7.4e-05 23.5 0.1 7.1 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM58701.1 - 1.5e-05 25.2 0.6 0.84 10.0 0.0 4.2 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM58701.1 - 1.6e-05 24.4 6.6 0.00042 19.7 0.1 3.3 1 1 3 4 4 4 2 WD40-like domain BBS2_Mid PF14783.6 KFM58701.1 - 0.0011 19.0 0.1 0.093 12.8 0.0 3.1 1 1 2 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KFM58701.1 - 0.0048 15.6 0.9 0.018 13.7 0.9 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Hira PF07569.11 KFM58701.1 - 0.02 14.7 1.6 1.6 8.4 0.1 3.0 3 1 0 3 3 3 0 TUP1-like enhancer of split Cluap1 PF10234.9 KFM58702.1 - 4.5e-92 308.2 8.9 5e-92 308.1 8.9 1.0 1 0 0 1 1 1 1 Clusterin-associated protein-1 Ndc80_HEC PF03801.13 KFM58702.1 - 0.0088 15.7 0.2 0.6 9.7 0.0 2.4 1 1 1 2 2 2 1 HEC/Ndc80p family DNA_primase_lrg PF04104.14 KFM58702.1 - 0.046 13.1 0.1 0.046 13.1 0.1 1.9 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Lectin_N PF03954.14 KFM58702.1 - 0.11 12.2 5.2 0.15 11.8 2.0 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 KFM58702.1 - 0.13 12.3 6.0 0.046 13.8 2.8 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KFM58702.1 - 1.6 8.5 7.1 13 5.6 4.1 2.7 2 1 0 2 2 2 0 Septum formation initiator Atg14 PF10186.9 KFM58702.1 - 7.8 5.5 10.1 8.5 5.4 8.7 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-H2C2_2 PF13465.6 KFM58703.1 - 1.4e-70 230.8 76.0 1e-08 35.2 0.9 11.1 11 0 0 11 11 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58703.1 - 3.4e-52 172.1 81.9 1.1e-05 25.7 2.0 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58703.1 - 1.9e-38 127.8 76.2 0.00015 22.3 0.9 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM58703.1 - 1.8e-21 75.6 61.8 0.0017 18.3 0.8 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFM58703.1 - 9.5e-21 73.5 65.0 0.00012 22.3 1.1 10.2 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM58703.1 - 3.7e-16 58.5 54.2 0.022 14.5 0.1 10.4 10 0 0 10 10 10 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM58703.1 - 2.9e-14 52.9 47.5 0.001 19.3 0.2 10.3 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM58703.1 - 2.2e-12 46.6 36.7 0.7 9.8 0.1 9.9 2 2 8 10 10 10 6 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM58703.1 - 1.9e-11 43.6 22.5 0.02 14.7 0.1 8.4 1 1 9 10 10 10 3 GAGA factor zf-C2H2_2 PF12756.7 KFM58703.1 - 4.2e-09 36.7 63.8 0.37 11.1 1.9 9.9 1 1 9 10 10 10 7 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM58703.1 - 1.4e-07 31.6 35.3 0.034 14.3 6.9 4.5 1 1 2 3 3 3 3 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 KFM58703.1 - 1.7e-06 27.8 52.1 1.1 9.2 1.5 9.8 6 2 4 10 10 10 4 Phorbol esters/diacylglycerol binding domain (C1 domain) BolA PF01722.18 KFM58703.1 - 1.1e-05 25.6 18.0 8 6.8 2.5 6.9 1 1 5 6 6 6 0 BolA-like protein zf-DBF PF07535.12 KFM58703.1 - 2.1e-05 24.5 34.8 2.8 8.1 0.2 9.1 9 0 0 9 9 9 2 DBF zinc finger DUF2256 PF10013.9 KFM58703.1 - 4.6e-05 23.4 35.0 14 5.9 0.0 9.9 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFM58703.1 - 0.00014 21.4 38.3 0.89 9.2 0.3 9.5 6 3 4 10 10 10 2 MYST family zinc finger domain zf-C2HC_2 PF13913.6 KFM58703.1 - 0.0021 17.9 36.4 0.39 10.7 0.4 9.1 9 0 0 9 9 9 1 zinc-finger of a C2HC-type DUF952 PF06108.12 KFM58703.1 - 0.023 14.7 0.9 24 5.0 0.0 4.6 1 1 6 7 7 7 0 Protein of unknown function (DUF952) zf-HIT PF04438.16 KFM58703.1 - 0.024 14.5 50.0 0.92 9.4 0.4 10.0 10 0 0 10 10 10 0 HIT zinc finger Tox-HNH-HHH PF15637.6 KFM58703.1 - 0.029 14.5 6.0 31 4.8 0.0 4.5 1 1 1 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Sec23_Sec24 PF04810.15 KFM58703.1 - 0.069 13.2 35.3 12 6.0 0.2 9.5 6 4 4 10 10 10 0 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM58703.1 - 0.095 12.7 38.0 1.2 9.2 2.1 5.5 5 0 0 5 5 5 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 KFM58703.1 - 0.12 12.3 37.5 19 5.3 0.2 9.6 10 0 0 10 10 10 0 Prokaryotic RING finger family 1 TRAF6_Z2 PF18048.1 KFM58703.1 - 0.2 11.7 47.7 4 7.6 0.4 10.1 10 0 0 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_15 PF17032.5 KFM58703.1 - 0.96 10.2 38.0 7.7 7.4 3.1 5.4 1 1 4 6 6 6 0 zinc-ribbon family MULE PF10551.9 KFM58704.1 - 2.2e-18 66.4 0.0 9.5e-11 42.0 0.0 2.6 2 0 0 2 2 2 2 MULE transposase domain FLYWCH PF04500.16 KFM58704.1 - 1e-11 44.8 2.3 1.8e-11 44.0 2.3 1.4 1 0 0 1 1 1 1 FLYWCH zinc finger domain DDE_Tnp_ISL3 PF01610.17 KFM58704.1 - 0.058 13.1 0.0 10 5.7 0.0 2.7 3 0 0 3 3 3 0 Transposase YozE_SAM_like PF06855.12 KFM58704.1 - 0.059 13.6 1.5 43 4.4 0.1 3.5 3 0 0 3 3 3 0 YozE SAM-like fold Chromo_shadow PF01393.19 KFM58704.1 - 0.065 13.3 0.4 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Chromo shadow domain RNaseH_like PF04308.12 KFM58704.1 - 0.083 12.8 0.0 15 5.4 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease H-like DDE_Tnp_1_7 PF13843.6 KFM58705.1 - 4.8e-72 243.2 0.0 5.9e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 RAC_head PF16717.5 KFM58706.1 - 7.9e-18 65.2 16.6 7.9e-18 65.2 16.6 4.6 4 2 0 5 5 5 1 Ribosome-associated complex head domain DnaJ PF00226.31 KFM58706.1 - 1.4e-16 60.3 3.1 1.4e-16 60.3 3.1 3.1 3 0 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.31 KFM58706.1 - 8.3e-15 54.7 3.7 1.8e-09 37.7 0.0 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM58706.1 - 1.5e-08 34.8 6.6 8e-06 26.0 0.3 4.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Nuc_sug_transp PF04142.15 KFM58707.1 - 6.2e-42 143.9 11.5 6.9e-42 143.7 11.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF4029 PF13221.6 KFM58707.1 - 0.079 13.6 0.7 0.079 13.6 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4029) Peptidase_U4 PF03419.13 KFM58707.1 - 0.2 10.9 6.0 0.24 10.6 6.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA UAA PF08449.11 KFM58707.1 - 0.3 10.2 9.1 0.47 9.6 9.1 1.5 1 1 0 1 1 1 0 UAA transporter family Nuc_sug_transp PF04142.15 KFM58708.1 - 4.3e-54 183.8 15.4 4.8e-54 183.6 15.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.6 KFM58708.1 - 2.4e-05 24.1 4.6 2.4e-05 24.1 4.6 1.6 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter EamA PF00892.20 KFM58708.1 - 6.2e-05 23.2 10.9 0.00025 21.2 10.9 1.9 1 1 0 1 1 1 1 EamA-like transporter family CRT-like PF08627.10 KFM58708.1 - 0.0002 20.5 2.7 0.0002 20.5 2.7 1.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 KFM58708.1 - 0.0019 17.5 11.1 0.0023 17.2 11.1 1.2 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KFM58708.1 - 0.0065 15.7 10.3 0.0078 15.5 9.7 1.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport COX4_pro_2 PF07835.12 KFM58708.1 - 0.023 14.8 0.1 0.089 12.9 0.1 2.0 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Strumpellin PF10266.9 KFM58709.1 - 0 1663.3 18.5 0 1663.1 18.5 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin FAD_SOX PF18371.1 KFM58709.1 - 0.017 15.5 0.1 0.5 10.8 0.0 3.3 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase YlbD_coat PF14071.6 KFM58709.1 - 0.05 13.8 3.6 0.34 11.2 3.6 2.5 1 0 0 1 1 1 0 Putative coat protein Gelsolin PF00626.22 KFM58710.1 - 6.3e-85 279.1 0.2 1.2e-16 60.3 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat PHZA_PHZB PF03284.13 KFM58710.1 - 0.035 13.7 0.3 0.22 11.1 0.0 2.5 3 0 0 3 3 3 0 Phenazine biosynthesis protein A/B DM13 PF10517.9 KFM58710.1 - 0.036 14.6 0.1 11 6.7 0.0 4.2 5 0 0 5 5 5 0 Electron transfer DM13 DEAD PF00270.29 KFM58711.1 - 1.2e-41 142.4 0.2 1.7e-41 141.9 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM58711.1 - 8.3e-28 97.0 1.9 1.9e-27 95.8 0.4 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KFM58711.1 - 0.081 12.2 0.1 0.21 10.9 0.1 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KFM58711.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain CSD PF00313.22 KFM58713.1 - 9.5e-05 22.2 0.5 0.024 14.5 0.0 3.6 3 0 0 3 3 3 2 'Cold-shock' DNA-binding domain p450 PF00067.22 KFM58714.1 - 6.8e-17 61.3 0.0 7e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSCB_C PF07743.13 KFM58714.1 - 0.15 12.6 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain RVT_1 PF00078.27 KFM58716.1 - 7e-16 58.4 0.1 8e-16 58.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_1 PF01344.25 KFM58717.1 - 6.9e-39 131.2 4.1 3.4e-11 42.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFM58717.1 - 1.6e-34 117.5 5.2 5.2e-07 29.8 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM58717.1 - 1.3e-31 107.8 9.4 2.7e-06 27.4 0.1 6.5 4 3 2 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KFM58717.1 - 1.8e-29 101.2 1.3 0.00039 20.3 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFM58717.1 - 1.9e-29 100.5 11.6 1.1e-06 28.4 0.0 7.1 6 2 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFM58717.1 - 1.6e-27 95.2 10.8 1.5e-09 37.7 0.0 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain tRNA_Me_trans PF03054.16 KFM58718.1 - 1e-86 291.0 0.0 1.2e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase HhH-GPD PF00730.25 KFM58719.1 - 2.6e-23 82.5 0.0 4.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFM58719.1 - 1.1e-09 37.6 0.0 2.5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif MMTV_SAg PF01054.17 KFM58719.1 - 0.0022 17.6 1.6 0.0051 16.4 1.6 1.5 1 1 0 1 1 1 1 Mouse mammary tumour virus superantigen Imm70 PF15601.6 KFM58719.1 - 0.1 12.1 0.7 0.21 11.2 0.7 1.4 1 0 0 1 1 1 0 Immunity protein 70 HHH_5 PF14520.6 KFM58719.1 - 0.14 12.7 0.1 2.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain TMEM18 PF14770.6 KFM58721.1 - 1e-47 161.0 4.5 1.2e-47 160.7 4.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 Nrap_D5 PF17406.2 KFM58721.1 - 0.0063 16.3 1.2 0.087 12.6 0.2 2.2 2 1 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 PLD_C PF12357.8 KFM58721.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Phospholipase D C terminal WH2 PF02205.20 KFM58723.1 - 3.2e-12 45.9 0.2 9.9e-12 44.3 0.1 1.9 2 0 0 2 2 2 1 WH2 motif MFS_1 PF07690.16 KFM58724.1 - 8.5e-06 24.9 0.9 8.9e-06 24.9 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFM58725.1 - 0.00019 20.5 0.6 0.00021 20.3 0.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CRAL_TRIO PF00650.20 KFM58726.1 - 6.6e-22 77.9 0.0 1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM58726.1 - 0.0023 18.1 0.4 0.003 17.7 0.2 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM58726.1 - 0.032 14.4 0.1 0.099 12.8 0.0 1.9 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain CH PF00307.31 KFM58727.1 - 2.1e-16 60.1 0.0 2.8e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM58727.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain HAP1_N PF04849.13 KFM58728.1 - 0.0055 15.9 0.9 0.0055 15.9 0.9 2.0 1 1 0 2 2 2 1 HAP1 N-terminal conserved region SPATA24 PF15175.6 KFM58728.1 - 0.043 13.7 8.5 0.23 11.3 0.7 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 AvrB_AvrC PF05394.11 KFM58728.1 - 0.11 11.7 0.9 0.11 11.6 0.9 1.1 1 0 0 1 1 1 0 Avirulence protein TFIIF_beta PF02270.15 KFM58728.1 - 0.11 12.6 0.2 0.43 10.8 0.1 1.9 2 1 0 2 2 2 0 TFIIF, beta subunit HTH domain HD_5 PF13487.6 KFM58728.1 - 0.13 12.5 0.4 0.31 11.3 0.1 1.7 2 0 0 2 2 2 0 HD domain DUF1319 PF07028.11 KFM58728.1 - 0.36 11.1 8.0 0.058 13.6 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Spectrin PF00435.21 KFM58728.1 - 0.38 11.2 5.7 0.17 12.4 2.7 1.7 1 1 1 2 2 2 0 Spectrin repeat Phage_lysis PF03245.13 KFM58728.1 - 0.44 10.7 3.2 2.1 8.5 0.4 2.1 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein zf-RING_5 PF14634.6 KFM58729.1 - 5.5e-06 26.3 11.4 1.7e-05 24.7 11.5 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM58729.1 - 6.9e-06 25.8 8.9 6.4e-05 22.7 5.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM58729.1 - 1.2e-05 25.1 10.0 1.8e-05 24.5 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM58729.1 - 1.4e-05 25.0 7.4 2.2e-05 24.4 7.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM58729.1 - 9.6e-05 22.2 5.5 9.6e-05 22.2 5.5 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFM58729.1 - 0.002 17.9 6.3 0.18 11.6 2.2 2.3 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KFM58729.1 - 0.0062 16.9 11.9 0.015 15.6 11.8 1.7 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFM58729.1 - 0.022 14.9 10.1 0.26 11.5 10.3 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 KFM58729.1 - 0.04 13.9 8.2 0.96 9.5 0.5 2.1 1 1 1 2 2 2 0 zinc-ribbons DUF832 PF05734.11 KFM58729.1 - 0.068 12.6 0.7 0.078 12.5 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) FAM76 PF16046.5 KFM58729.1 - 0.18 11.1 6.6 0.22 10.9 6.6 1.1 1 0 0 1 1 1 0 FAM76 protein zf-H2C2_2 PF13465.6 KFM58729.1 - 0.2 12.2 0.4 0.2 12.2 0.4 2.6 3 0 0 3 3 3 0 Zinc-finger double domain DZR PF12773.7 KFM58729.1 - 0.37 10.8 9.3 6.3 6.9 9.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 KFM58729.1 - 1 9.6 9.3 0.23 11.6 5.8 1.8 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 KFM58729.1 - 1 9.2 12.8 17 5.4 12.9 2.5 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) YdjO PF14169.6 KFM58729.1 - 2.1 8.1 7.5 0.79 9.5 2.0 2.1 1 1 1 2 2 2 0 Cold-inducible protein YdjO Elf1 PF05129.13 KFM58729.1 - 2.3 8.3 11.1 1.2e+02 2.9 11.1 2.1 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like UNC-50 PF05216.13 KFM58730.1 - 9.3e-87 290.2 23.6 1e-86 290.0 23.6 1.0 1 0 0 1 1 1 1 UNC-50 family Orai-1 PF07856.12 KFM58730.1 - 3 7.5 13.0 0.3 10.8 7.1 2.1 1 1 1 2 2 2 0 Mediator of CRAC channel activity zf-H2C2_2 PF13465.6 KFM58731.1 - 2e-15 56.4 9.3 2.4e-06 27.7 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58731.1 - 4e-10 39.6 19.3 0.00038 20.7 0.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM58731.1 - 2.9e-09 36.5 1.6 2.9e-09 36.5 1.6 3.7 3 2 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM58731.1 - 4.1e-09 36.5 18.0 0.0014 19.3 0.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM58731.1 - 3e-05 24.2 8.3 0.023 15.1 0.6 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Baculo_IE-1 PF05290.11 KFM58731.1 - 0.0052 16.7 2.4 0.89 9.5 0.1 2.8 1 1 2 3 3 3 1 Baculovirus immediate-early protein (IE-0) UBZ_FAAP20 PF15750.5 KFM58731.1 - 0.017 15.0 1.9 3.3 7.7 0.5 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger BolA PF01722.18 KFM58731.1 - 0.017 15.4 0.5 0.91 9.9 0.1 2.6 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_2 PF12756.7 KFM58731.1 - 0.044 14.1 8.9 4.7 7.6 0.2 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 KFM58731.1 - 0.066 13.4 6.6 4.8 7.4 0.2 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger zf-Di19 PF05605.12 KFM58731.1 - 0.088 13.1 8.4 7.5 6.9 0.4 2.9 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding YyzF PF14116.6 KFM58731.1 - 0.095 12.7 1.4 15 5.8 0.0 3.0 3 0 0 3 3 3 0 YyzF-like protein TRAF6_Z2 PF18048.1 KFM58731.1 - 0.12 12.5 1.3 0.12 12.5 1.3 2.9 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 LIM PF00412.22 KFM58731.1 - 0.13 12.5 4.9 6.7 7.0 0.1 2.7 3 0 0 3 3 3 0 LIM domain Prok-RING_4 PF14447.6 KFM58731.1 - 0.16 11.9 4.2 4.9 7.1 0.1 2.6 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 PyrI_C PF02748.15 KFM58731.1 - 0.18 11.7 7.2 4.1 7.4 0.1 3.1 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.9 KFM58731.1 - 0.27 11.3 5.6 19 5.4 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger domain C1_1 PF00130.22 KFM58731.1 - 0.38 10.7 9.0 8.4 6.4 0.4 2.9 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 KFM58731.1 - 0.45 10.5 6.3 0.63 10.1 2.8 2.5 1 1 1 2 2 2 0 zinc-ribbons Zf_RING PF16744.5 KFM58731.1 - 0.48 10.6 4.3 2 8.6 0.1 2.5 2 1 1 3 3 3 0 KIAA1045 RING finger zf-C2HC5 PF06221.13 KFM58731.1 - 0.57 10.2 7.6 4.2 7.4 0.3 3.1 1 1 2 3 3 3 0 Putative zinc finger motif, C2HC5-type GAGA PF09237.11 KFM58731.1 - 0.63 9.9 7.4 4 7.3 0.3 2.8 1 1 2 3 3 3 0 GAGA factor zinc_ribbon_15 PF17032.5 KFM58731.1 - 0.63 10.8 6.9 0.91 10.3 1.1 2.4 1 1 1 2 2 2 0 zinc-ribbon family C1_2 PF03107.16 KFM58731.1 - 0.65 10.4 9.7 6.6 7.1 4.8 3.1 2 1 0 2 2 2 0 C1 domain zf-C4_ClpX PF06689.13 KFM58731.1 - 3.7 7.5 7.8 1.8 8.5 0.8 2.9 3 0 0 3 3 3 0 ClpX C4-type zinc finger zf-C2H2 PF00096.26 KFM58732.1 - 7.4e-16 57.6 19.9 1.3e-06 28.5 0.3 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM58732.1 - 2.2e-15 56.3 18.6 5e-07 29.9 1.8 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM58732.1 - 3.1e-12 46.2 18.6 3.9e-05 24.1 4.2 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM58732.1 - 3.6e-10 39.4 13.5 8.8e-05 22.2 1.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM58732.1 - 0.00012 22.3 14.1 0.38 11.1 1.4 3.0 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFM58732.1 - 0.00017 21.8 1.4 0.00042 20.5 0.4 1.9 1 1 1 2 2 2 1 BolA-like protein zf-Di19 PF05605.12 KFM58732.1 - 0.001 19.3 10.8 0.19 12.1 0.9 2.5 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KFM58732.1 - 0.0013 18.5 5.4 0.0067 16.2 0.3 2.9 1 1 2 3 3 3 1 GAGA factor zf-met PF12874.7 KFM58732.1 - 0.0016 18.8 20.4 0.0051 17.2 1.2 3.9 3 1 0 3 3 3 2 Zinc-finger of C2H2 type Cript PF10235.9 KFM58732.1 - 0.0031 18.0 3.7 0.024 15.2 0.2 2.2 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zf-C2H2_jaz PF12171.8 KFM58732.1 - 0.0044 17.3 15.3 0.14 12.4 0.0 3.7 4 1 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM58732.1 - 0.0078 16.0 7.8 0.82 9.6 0.2 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KFM58732.1 - 0.0088 15.6 5.9 0.54 9.9 0.7 3.0 2 1 1 3 3 3 2 MYST family zinc finger domain zf-C2HE PF16278.5 KFM58732.1 - 0.011 16.2 11.7 0.32 11.5 0.2 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-RING_2 PF13639.6 KFM58732.1 - 0.016 15.5 4.9 2.4 8.6 0.1 3.1 3 0 0 3 3 3 0 Ring finger domain ADK_lid PF05191.14 KFM58732.1 - 0.028 14.4 0.5 0.028 14.4 0.5 1.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM58732.1 - 0.058 13.5 5.1 1.6 8.9 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) OrsD PF12013.8 KFM58732.1 - 0.094 13.2 11.8 0.34 11.3 0.8 3.0 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_6 PF13912.6 KFM58732.1 - 0.16 12.0 0.3 0.16 12.0 0.3 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFM58732.1 - 0.2 12.4 6.4 1.7 9.3 1.4 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats FdhE PF04216.12 KFM58732.1 - 0.2 11.5 2.0 0.29 11.0 2.0 1.4 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation NADH-G_4Fe-4S_3 PF10588.9 KFM58732.1 - 0.65 9.6 0.2 0.65 9.6 0.2 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Zn-C2H2_12 PF18112.1 KFM58732.1 - 3.2 8.3 13.9 1.7 9.2 1.0 3.5 4 1 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain UBZ_FAAP20 PF15750.5 KFM58732.1 - 7.5 6.6 7.4 39 4.3 0.2 3.1 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-H2C2_2 PF13465.6 KFM58733.1 - 1.9e-14 53.3 7.9 2.3e-08 34.1 1.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58733.1 - 4.9e-12 45.6 20.5 1.6e-06 28.3 2.8 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58733.1 - 3.6e-09 36.7 17.6 0.00018 22.0 2.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFM58733.1 - 4.1e-08 33.3 13.2 0.00075 19.8 0.6 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM58733.1 - 4.2e-05 23.4 14.3 0.00014 21.8 0.8 3.3 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM58733.1 - 0.0057 17.0 6.3 0.35 11.2 1.7 2.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-RING_2 PF13639.6 KFM58733.1 - 0.0072 16.6 4.4 0.47 10.8 0.1 2.2 2 0 0 2 2 2 2 Ring finger domain BolA PF01722.18 KFM58733.1 - 0.008 16.4 0.4 0.015 15.6 0.2 1.6 1 1 1 2 2 2 1 BolA-like protein Cript PF10235.9 KFM58733.1 - 0.009 16.6 0.5 0.013 16.0 0.3 1.4 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT zf-BED PF02892.15 KFM58733.1 - 0.015 15.3 17.3 0.43 10.7 1.1 3.2 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_9 PF16293.5 KFM58733.1 - 0.033 14.0 3.0 1 9.3 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 KFM58733.1 - 0.037 14.3 10.3 0.17 12.2 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-UBR PF02207.20 KFM58733.1 - 0.064 13.4 2.8 0.081 13.1 2.8 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_3rep PF18868.1 KFM58733.1 - 0.077 13.7 3.2 1.9 9.2 2.6 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zf_RING PF16744.5 KFM58733.1 - 0.16 12.1 2.0 2.7 8.2 0.1 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger GAGA PF09237.11 KFM58733.1 - 0.25 11.2 4.5 0.41 10.5 0.8 2.2 1 1 1 2 2 2 0 GAGA factor UBZ_FAAP20 PF15750.5 KFM58733.1 - 0.26 11.2 2.2 10 6.2 0.7 2.3 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-MYST PF17772.1 KFM58733.1 - 0.32 10.6 3.7 1.5 8.5 0.7 2.3 2 1 0 2 2 2 0 MYST family zinc finger domain DUF2256 PF10013.9 KFM58733.1 - 0.5 10.5 2.8 4.2 7.6 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 KFM58733.1 - 1.4 8.6 4.0 11 5.7 0.5 2.4 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 KFM58733.1 - 3.3 8.2 13.1 1.3 9.5 1.3 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger TGFb_propeptide PF00688.18 KFM58734.1 - 2.3e-14 53.8 0.0 3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFM58734.1 - 1.4e-12 48.5 0.0 2.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain HMG_box PF00505.19 KFM58735.1 - 6.8e-14 52.0 0.1 1.5e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.8 KFM58735.1 - 8.1e-07 30.1 0.4 1.7e-06 29.1 0.4 1.6 1 1 0 1 1 1 1 Sox developmental protein N terminal HMG_box_2 PF09011.10 KFM58735.1 - 0.0098 16.5 0.1 0.019 15.6 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain cobW PF02492.19 KFM58736.1 - 2.1e-29 102.4 0.0 2.6e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KFM58736.1 - 3.6e-06 26.2 0.4 0.0021 17.1 0.1 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KFM58736.1 - 0.0045 17.5 0.0 0.0067 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFM58736.1 - 0.012 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain KAP_NTPase PF07693.14 KFM58736.1 - 0.016 14.5 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.23 KFM58736.1 - 0.02 14.9 0.0 0.042 13.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KFM58736.1 - 0.084 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 KFM58736.1 - 0.12 12.8 0.0 1.8 9.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KFM58736.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 KFM58736.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 KFM58736.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DDE_3 PF13358.6 KFM58739.1 - 5.1e-05 23.1 0.0 6.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SWIM PF04434.17 KFM58740.1 - 0.00026 20.6 7.5 0.003 17.2 0.2 2.6 2 0 0 2 2 2 2 SWIM zinc finger PDEase_I PF00233.19 KFM58741.1 - 4.8e-23 82.1 0.6 8.6e-23 81.3 0.0 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DUF4538 PF15061.6 KFM58742.1 - 0.13 12.1 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF682 PF05081.12 KFM58742.1 - 0.18 11.5 1.2 0.48 10.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF682) HLH PF00010.26 KFM58743.1 - 2e-17 62.9 2.1 3.9e-17 61.9 2.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAM76 PF16046.5 KFM58743.1 - 0.0023 17.4 1.2 0.0029 17.0 1.2 1.0 1 0 0 1 1 1 1 FAM76 protein AROS PF15684.5 KFM58743.1 - 0.0042 17.6 1.9 0.0056 17.2 1.9 1.1 1 0 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 CCDC106 PF15794.5 KFM58743.1 - 0.027 14.2 1.6 0.04 13.6 1.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 L31 PF09784.9 KFM58743.1 - 0.051 14.0 0.6 0.086 13.3 0.6 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 PMP22_Claudin PF00822.20 KFM58744.1 - 0.0005 20.0 3.7 0.0054 16.6 0.0 2.3 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFM58744.1 - 0.22 11.3 9.3 0.17 11.6 6.4 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 KFM58744.1 - 0.31 10.6 13.7 0.013 15.1 5.3 2.3 1 1 0 2 2 2 0 SUR7/PalI family YoqO PF14037.6 KFM58744.1 - 9.1 6.9 14.4 0.99 10.0 6.0 2.6 2 1 1 3 3 3 0 YoqO-like protein Neuralized PF07177.12 KFM58747.1 - 7.7e-21 74.7 0.0 1.1e-20 74.1 0.0 1.5 1 1 0 1 1 1 1 Neuralized bZIP_2 PF07716.15 KFM58748.1 - 8.2e-16 57.8 11.0 1.2e-15 57.3 11.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM58748.1 - 2.8e-07 30.5 12.3 4.9e-07 29.7 12.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.11 KFM58748.1 - 0.008 16.0 2.6 0.02 14.8 2.6 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DMPK_coil PF08826.10 KFM58748.1 - 0.05 13.7 2.9 0.097 12.8 2.9 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF1465 PF07323.12 KFM58748.1 - 0.056 13.3 0.8 0.088 12.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) bZIP_Maf PF03131.17 KFM58748.1 - 0.071 13.6 8.2 0.11 13.0 8.2 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2514 PF10721.9 KFM58748.1 - 0.083 12.9 1.1 0.16 12.0 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Csm1_N PF18504.1 KFM58748.1 - 0.19 12.1 3.4 0.36 11.2 3.2 1.6 1 1 0 1 1 1 0 Csm1 N-terminal domain LIM PF00412.22 KFM58749.1 - 5.5e-33 113.0 33.3 1.2e-11 44.7 8.2 3.1 3 0 0 3 3 3 3 LIM domain Na_H_Exchanger PF00999.21 KFM58751.1 - 2.7e-41 141.7 23.0 3.5e-41 141.3 23.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_S17 PF00366.20 KFM58751.1 - 0.11 12.6 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein S17 Acetyltransf_18 PF18014.1 KFM58754.1 - 1.6e-17 63.5 0.0 2.7e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM58754.1 - 1.4e-07 31.7 0.4 0.0017 18.6 0.1 3.1 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM58754.1 - 0.00094 19.1 0.0 0.73 9.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM58754.1 - 0.025 15.0 0.2 0.33 11.4 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM58754.1 - 0.026 14.5 0.0 0.61 10.1 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein GNAT_acetyltran PF12746.7 KFM58754.1 - 0.083 12.4 0.2 0.56 9.7 0.2 2.1 1 1 0 1 1 1 0 GNAT acetyltransferase Apt1 PF10351.9 KFM58756.1 - 1.3e-107 360.6 12.2 3e-75 253.9 0.4 2.6 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 KFM58756.1 - 5.7e-29 101.2 0.0 1.2e-28 100.2 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KFM58756.1 - 7.1e-07 29.3 1.8 2.5e-06 27.5 1.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_WPPW PF10359.9 KFM58756.1 - 0.0017 17.3 0.6 0.0017 17.3 0.6 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF1398 PF07166.11 KFM58756.1 - 0.042 13.9 0.9 0.13 12.3 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) CCDC-167 PF15188.6 KFM58756.1 - 0.53 10.7 3.9 1.7 9.0 3.9 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Med13_N PF11597.8 KFM58759.1 - 1.3e-07 31.3 0.1 1.6e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal EDR1 PF14381.6 KFM58759.1 - 0.078 12.7 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 CRAL_TRIO PF00650.20 KFM58761.1 - 2.7e-32 111.7 0.0 5.3e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM58761.1 - 1.9e-06 28.1 0.0 4e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM58761.1 - 0.057 13.6 0.6 0.3 11.3 0.3 2.2 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 KFM58762.1 - 1.6e-22 79.9 0.4 2.7e-22 79.2 0.3 1.4 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM58762.1 - 8.5e-06 26.0 0.3 1.6e-05 25.1 0.3 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM58762.1 - 0.00036 20.6 0.1 0.00093 19.3 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SIX1_SD PF16878.5 KFM58762.1 - 0.0026 18.3 0.2 0.011 16.2 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain CRAL_TRIO PF00650.20 KFM58763.1 - 6.9e-05 22.6 0.2 0.00014 21.6 0.1 1.6 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM58763.1 - 0.00014 21.9 0.2 0.00024 21.2 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF2897 PF11446.8 KFM58763.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Meis_PKNOX_N PF16493.5 KFM58765.1 - 4.7e-38 129.4 1.5 1.1e-37 128.3 1.5 1.6 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFM58765.1 - 1e-18 66.9 2.1 2.1e-18 65.9 2.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFM58765.1 - 4.8e-08 32.7 0.3 1.4e-07 31.3 0.3 1.8 1 0 0 1 1 1 1 Homeodomain CFAP91 PF14738.6 KFM58767.1 - 0.015 15.3 8.4 0.015 15.3 8.4 1.0 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 CFAP91 PF14738.6 KFM58768.1 - 0.037 14.1 2.4 0.058 13.4 2.4 1.3 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 Biotin_lipoyl_2 PF13533.6 KFM58768.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Biotin-lipoyl like CN_hydrolase PF00795.22 KFM58769.1 - 5.9e-61 206.1 0.0 6.6e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-C2H2 PF00096.26 KFM58770.1 - 9.8e-41 136.0 125.4 1.4e-05 25.3 2.9 15.3 15 0 0 15 15 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58770.1 - 2.8e-33 111.7 119.3 0.00051 20.7 1.8 15.6 15 0 0 15 15 15 14 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM58770.1 - 1.5e-13 50.5 106.2 2.7e-07 30.7 0.9 15.8 16 1 0 16 16 14 8 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFM58770.1 - 7.3e-11 41.8 86.1 0.00064 19.7 0.5 13.8 14 0 0 14 14 14 8 C2H2-type zinc finger DUF2225 PF09986.9 KFM58770.1 - 3.4e-05 23.7 0.3 3.4e-05 23.7 0.3 5.9 6 1 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2225) SET PF00856.28 KFM58770.1 - 0.0039 17.6 0.0 0.065 13.6 0.0 2.8 1 1 0 1 1 1 1 SET domain zf-C2H2_jaz PF12171.8 KFM58770.1 - 0.0061 16.8 88.4 0.016 15.5 2.1 13.5 14 0 0 14 14 14 6 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KFM58770.1 - 0.019 14.6 0.1 0.019 14.6 0.1 8.5 8 2 2 10 10 10 0 Zinc-fingers and homeoboxes C2H2 finger domain TF_Zn_Ribbon PF08271.12 KFM58770.1 - 0.14 11.7 21.2 17 5.0 0.4 7.9 8 0 0 8 8 8 0 TFIIB zinc-binding Arena_nucleocap PF00843.17 KFM58770.1 - 0.21 10.5 0.1 0.35 9.7 0.1 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain NinF PF05810.12 KFM58770.1 - 0.26 11.2 3.2 10 6.1 0.1 3.7 3 0 0 3 3 3 0 NinF protein FYVE PF01363.21 KFM58770.1 - 0.28 11.3 0.0 0.28 11.3 0.0 10.6 7 3 2 9 9 8 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFM58770.1 - 0.61 10.5 73.4 0.32 11.4 3.8 11.8 3 1 7 11 11 11 0 C2H2 type zinc-finger (2 copies) AT_hook PF02178.19 KFM58770.1 - 1.4 9.0 19.0 0.81 9.8 6.2 3.0 2 0 0 2 2 2 0 AT hook motif zf_UBZ PF18439.1 KFM58770.1 - 1.9 8.2 67.5 1.2 8.8 0.4 12.7 14 0 0 14 14 14 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KFM58770.1 - 2.3 8.1 36.4 2.5 8.0 0.5 9.0 9 1 1 10 10 10 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 KFM58772.1 - 8.9e-11 41.6 90.7 0.0021 18.4 1.2 9.8 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58772.1 - 9.9e-10 38.4 82.1 0.016 16.0 1.5 10.4 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM58772.1 - 1.4e-08 34.8 34.9 0.0033 17.7 3.2 6.4 6 0 0 6 6 5 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFM58772.1 - 0.00013 22.2 0.1 0.00013 22.2 0.1 8.9 9 0 0 9 9 9 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM58772.1 - 0.00041 20.0 7.6 0.00041 20.0 7.6 7.4 7 1 0 7 7 6 2 C2H2-type zinc-finger domain Zap1_zf2 PF18217.1 KFM58772.1 - 0.0047 16.9 1.4 0.0047 16.9 1.4 5.2 4 0 0 4 4 3 1 Zap1 zinc finger 2 zf-met PF12874.7 KFM58772.1 - 0.013 15.9 39.2 0.28 11.6 3.3 6.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Pox_I1 PF03289.13 KFM58772.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus protein I1 zf-RING_7 PF02591.15 KFM58772.1 - 0.19 11.9 2.9 48 4.3 0.0 4.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain FOXP-CC PF16159.5 KFM58772.1 - 0.19 12.4 0.2 0.19 12.4 0.2 8.4 3 1 6 9 9 9 0 FOXP coiled-coil domain PyrI_C PF02748.15 KFM58772.1 - 0.2 11.6 0.1 0.2 11.6 0.1 5.0 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.9 KFM58772.1 - 5.4 7.2 13.5 26 5.0 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger domain LRR_8 PF13855.6 KFM58774.1 - 8.7e-26 89.5 7.9 1.2e-09 37.8 0.3 4.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFM58774.1 - 5.3e-19 68.0 4.7 2.2e-05 24.7 0.0 5.1 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM58774.1 - 1.9e-08 33.7 5.9 1.9 8.7 0.1 7.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 KFM58774.1 - 1.2e-06 28.2 7.9 30 5.7 0.0 8.2 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.6 KFM58774.1 - 7.7e-06 25.5 0.5 0.0058 16.2 0.1 2.7 3 0 0 3 3 3 2 Leucine-rich repeat fn3 PF00041.21 KFM58774.1 - 0.00035 20.9 0.4 0.00035 20.9 0.4 2.7 2 1 0 2 2 2 1 Fibronectin type III domain Chitin_bind_4 PF00379.23 KFM58775.1 - 4e-07 30.5 10.1 9.1e-07 29.3 10.1 1.7 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM58776.1 - 2.1e-10 40.9 11.2 5.7e-10 39.6 11.2 1.8 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM58779.1 - 1.4e-12 48.0 8.4 3.9e-12 46.5 8.4 1.8 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM58784.1 - 5.5e-10 39.6 1.6 8.7e-10 39.0 1.6 1.3 1 0 0 1 1 1 1 Insect cuticle protein RAMA PF18755.1 KFM58785.1 - 8.9e-28 96.9 0.1 1.3e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated BSP_II PF05432.11 KFM58785.1 - 2 8.0 8.3 9.1 5.9 2.5 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) MADF_DNA_bdg PF10545.9 KFM58786.1 - 2.3e-18 66.3 1.5 2.8e-18 66.0 1.5 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 KFM58786.1 - 0.00011 22.5 1.5 0.00019 21.7 1.5 1.4 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 KFM58789.1 - 2.9e-16 59.7 1.3 2.9e-16 59.7 1.3 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM58790.1 - 8.7e-07 28.8 0.0 1.7e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KFM58792.1 - 2.5e-13 50.1 1.4 2.5e-13 50.1 1.4 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM58793.1 - 1.2e-07 31.6 0.2 2.7e-07 30.5 0.2 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Mucin_bdg PF03272.13 KFM58793.1 - 0.087 12.9 0.6 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module COesterase PF00135.28 KFM58795.1 - 4.9e-159 530.5 0.0 5.8e-159 530.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM58795.1 - 1.5e-07 31.5 0.0 3.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4019 PF13211.6 KFM58795.1 - 0.13 12.6 0.5 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) zf-RING_9 PF13901.6 KFM58796.1 - 9.3e-43 146.6 16.8 1.1e-42 146.4 16.8 1.0 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 KFM58796.1 - 0.00087 19.2 10.4 0.00087 19.2 10.4 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.29 KFM58796.1 - 0.01 15.7 9.8 0.01 15.7 9.8 2.4 2 1 0 2 2 2 0 PHD-finger RVT_3 PF13456.6 KFM58796.1 - 0.03 14.1 0.2 0.053 13.3 0.2 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Zn-ribbon_8 PF09723.10 KFM58796.1 - 0.49 10.5 9.9 0.32 11.1 3.3 2.6 1 1 1 2 2 2 0 Zinc ribbon domain Med10 PF09748.9 KFM58799.1 - 0.11 12.4 1.1 0.51 10.3 0.1 2.4 2 2 1 3 3 3 0 Transcription factor subunit Med10 of Mediator complex COG5 PF10392.9 KFM58799.1 - 0.7 10.1 9.2 1.3 9.2 0.5 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Fmp27_WPPW PF10359.9 KFM58799.1 - 2.4 6.9 7.6 11 4.7 7.6 1.9 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain COesterase PF00135.28 KFM58800.1 - 1.6e-83 281.3 0.0 1.9e-83 281.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM58800.1 - 0.0007 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM58800.1 - 0.015 15.9 0.9 0.05 14.2 0.5 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family TAFII28 PF04719.14 KFM58804.1 - 2e-38 130.3 0.1 3.3e-38 129.7 0.1 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KFM58804.1 - 3.9e-06 27.1 0.0 6.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LIN37 PF15306.6 KFM58804.1 - 0.13 12.5 3.4 0.19 12.0 3.4 1.2 1 0 0 1 1 1 0 LIN37 TFIIE-A_C PF11521.8 KFM58804.1 - 9.1 6.7 13.9 7.9 6.9 5.7 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha TMEM61 PF15105.6 KFM58806.1 - 0.085 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 TMEM61 protein family Homeodomain PF00046.29 KFM58807.1 - 2.6e-18 65.6 0.8 3.9e-18 65.0 0.8 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM58807.1 - 0.071 13.0 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain RRM_1 PF00076.22 KFM58808.1 - 1.2e-32 111.5 0.0 9e-11 41.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFM58808.1 - 0.012 15.9 0.0 0.15 12.3 0.0 2.6 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF3195 PF11424.8 KFM58808.1 - 0.17 12.0 0.0 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3195) SinI PF08671.10 KFM58808.1 - 0.27 11.1 0.6 11 5.9 0.1 2.6 2 0 0 2 2 2 0 Anti-repressor SinI Methyltransf_11 PF08241.12 KFM58809.1 - 2.9e-15 56.7 0.0 4.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM58809.1 - 2.1e-11 44.0 0.0 2.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM58809.1 - 1.3e-10 41.8 0.0 2.2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM58809.1 - 2.9e-10 40.8 0.0 5.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM58809.1 - 6.7e-06 26.0 0.0 9.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM58809.1 - 8.1e-06 25.3 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KFM58809.1 - 3.3e-05 23.6 0.0 4.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 KFM58809.1 - 0.0028 17.5 0.1 0.0047 16.8 0.1 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase ubiquitin PF00240.23 KFM58811.1 - 1.9e-05 24.3 0.4 4.6e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KFM58811.1 - 0.0045 16.8 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3573 PF12097.8 KFM58811.1 - 0.52 9.1 3.9 0.8 8.5 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) BTB PF00651.31 KFM58812.1 - 6.5e-26 90.7 0.0 1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Neur_chan_LBD PF02931.23 KFM58814.1 - 4.8e-43 147.1 0.3 5.9e-43 146.8 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM58814.1 - 2.9e-10 40.6 2.8 4.1e-10 40.1 2.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region HSDR_N PF04313.14 KFM58815.1 - 0.063 13.2 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Receptor_IA-2 PF11548.8 KFM58819.1 - 1.3e-10 41.1 0.0 1.3e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase receptor IA-2 DUF2163 PF09931.9 KFM58819.1 - 0.15 12.2 0.0 0.15 12.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) DDE_1 PF03184.19 KFM58820.1 - 5.5e-50 169.4 0.1 9.7e-50 168.6 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM58820.1 - 2.5e-12 46.6 0.0 1.9e-11 43.8 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM58820.1 - 0.0011 18.5 0.0 0.0036 16.9 0.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain TERT_thumb PF17984.1 KFM58821.1 - 0.084 12.8 0.0 0.084 12.8 0.0 1.0 1 0 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain Y_phosphatase PF00102.27 KFM58822.1 - 7.2e-49 166.5 0.3 1e-48 166.0 0.3 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HTH_Tnp_Tc3_2 PF01498.18 KFM58824.1 - 7.2e-16 58.2 6.5 1.5e-15 57.2 6.5 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58824.1 - 1.2e-15 57.5 0.8 9.9e-15 54.6 0.0 2.5 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM58824.1 - 0.0013 19.3 1.1 0.0013 19.3 1.1 2.8 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM58824.1 - 0.002 17.8 0.1 0.12 12.2 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM58824.1 - 0.042 13.9 2.0 0.065 13.3 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 KFM58824.1 - 0.048 13.8 0.9 0.17 12.0 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM58825.1 - 2.2e-16 59.8 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58825.1 - 1.2e-11 44.5 0.0 2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 KFM58826.1 - 4.1e-80 269.7 0.2 5.9e-80 269.2 0.2 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM58826.1 - 0.0003 21.5 9.2 0.00072 20.3 9.2 1.7 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon YL1 PF05764.13 KFM58826.1 - 0.0063 16.7 3.3 0.0063 16.7 3.3 1.5 2 0 0 2 2 2 1 YL1 nuclear protein DDE_Tnp_1 PF01609.21 KFM58826.1 - 0.035 13.7 0.0 0.11 12.1 0.0 1.9 1 1 0 1 1 1 0 Transposase DDE domain DUF4371 PF14291.6 KFM58827.1 - 0.0032 17.1 0.4 0.0063 16.2 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) 7tm_1 PF00001.21 KFM58829.1 - 1.3e-38 132.9 2.9 1.6e-38 132.6 2.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFM58829.1 - 0.00039 19.9 12.2 0.052 12.9 2.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv Yip1 PF04893.17 KFM58829.1 - 0.1 12.3 7.3 0.073 12.8 0.5 2.1 2 0 0 2 2 2 0 Yip1 domain DUF3671 PF12420.8 KFM58829.1 - 2 8.5 12.1 4.2 7.5 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function zf-C2H2_11 PF16622.5 KFM58829.1 - 3.8 7.4 11.5 3.1 7.6 6.8 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type HTH_Tnp_Tc3_2 PF01498.18 KFM58830.1 - 1.9e-16 60.1 2.2 3.9e-16 59.1 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58830.1 - 7.8e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Chitin_bind_4 PF00379.23 KFM58831.1 - 8e-10 39.1 1.9 1.2e-09 38.6 1.9 1.3 1 0 0 1 1 1 1 Insect cuticle protein DUF229 PF02995.17 KFM58832.1 - 9.2e-127 423.7 0.1 1.8e-126 422.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 KFM58832.1 - 5.5e-08 32.6 0.0 7.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFM58832.1 - 2.9e-05 23.8 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KFM58832.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DnaJ PF00226.31 KFM58833.1 - 3.3e-06 27.1 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KFM58833.1 - 0.036 14.1 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Pam16 Ribosomal_S10 PF00338.22 KFM58834.1 - 5.7e-13 48.9 0.0 8.8e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e WHEP-TRS PF00458.20 KFM58834.1 - 0.17 12.0 1.0 0.33 11.1 1.0 1.5 1 0 0 1 1 1 0 WHEP-TRS domain FAD_binding_7 PF03441.14 KFM58835.1 - 1.6e-77 259.6 1.5 2.2e-77 259.1 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFM58835.1 - 7.2e-28 97.6 0.0 7.3e-27 94.4 0.0 2.2 2 0 0 2 2 2 1 DNA photolyase DNA_photolyase PF00875.18 KFM58836.1 - 2.4e-10 40.7 0.0 2.5e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 DNA photolyase HMG_box PF00505.19 KFM58837.1 - 2.8e-24 85.3 3.3 2.8e-24 85.3 3.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM58837.1 - 5.3e-09 36.5 2.1 1.3e-08 35.3 2.1 1.7 1 0 0 1 1 1 1 HMG-box domain HTH_Tnp_Tc3_2 PF01498.18 KFM58838.1 - 2.8e-10 40.3 0.3 7.4e-10 38.9 0.3 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58838.1 - 2.4e-09 37.1 0.0 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.32 KFM58840.1 - 2e-09 37.9 0.9 0.0031 18.3 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM58840.1 - 0.0037 17.5 0.0 0.97 9.8 0.0 2.1 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM58842.1 - 2.7e-10 40.7 1.4 0.00052 20.8 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat TPR_8 PF13181.6 KFM58843.1 - 2e-09 36.9 6.0 0.00019 21.3 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM58843.1 - 1.1e-08 35.5 2.5 0.044 14.3 0.0 4.7 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM58843.1 - 1.6e-08 35.0 0.2 2.7e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM58843.1 - 1e-06 28.3 6.4 3.7e-06 26.5 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM58843.1 - 1.1e-05 25.1 0.3 0.0011 18.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM58843.1 - 1.1e-05 25.6 2.4 2e-05 24.8 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM58843.1 - 2.2e-05 24.9 2.0 0.024 15.4 0.0 5.0 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM58843.1 - 0.00014 21.7 0.1 0.00014 21.7 0.1 5.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFM58843.1 - 0.00039 20.7 1.2 0.39 11.1 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM58843.1 - 0.012 15.2 0.4 0.12 12.1 0.1 2.6 2 0 0 2 2 2 0 TPR repeat TPR_9 PF13371.6 KFM58843.1 - 0.026 14.7 0.1 0.2 11.8 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFM58843.1 - 0.038 13.2 0.2 0.41 9.8 0.0 2.2 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM58843.1 - 0.73 10.6 3.6 12 6.7 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Ran_BP1 PF00638.18 KFM58844.1 - 2.1e-184 602.8 24.0 5.8e-47 159.0 0.9 5.5 5 0 0 5 5 5 5 RanBP1 domain zf-RanBP PF00641.18 KFM58844.1 - 1.2e-21 75.7 44.9 4.9e-08 32.1 2.7 4.7 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others WH1 PF00568.23 KFM58844.1 - 2.9e-14 52.9 6.7 0.0012 18.8 0.1 5.7 5 0 0 5 5 5 4 WH1 domain VID27_PH PF17747.1 KFM58844.1 - 3.6e-06 27.2 6.8 0.0021 18.3 0.1 4.9 5 0 0 5 5 5 1 VID27 PH-like domain IR1-M PF12185.8 KFM58844.1 - 0.011 15.6 0.1 0.046 13.7 0.1 2.1 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain NEMO PF11577.8 KFM58844.1 - 0.014 15.4 3.1 0.045 13.8 3.1 1.8 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO zf-Sec23_Sec24 PF04810.15 KFM58844.1 - 0.028 14.5 8.1 7.7 6.7 0.0 4.8 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger Transposase_24 PF03004.14 KFM58844.1 - 8.3 6.5 9.8 2 8.5 5.4 2.3 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) PAH PF02671.21 KFM58845.1 - 7.4e-06 26.0 3.1 0.0025 17.9 0.1 3.0 2 0 0 2 2 2 2 Paired amphipathic helix repeat Glyoxalase_2 PF12681.7 KFM58845.1 - 0.034 14.1 0.1 0.27 11.2 0.1 2.5 2 0 0 2 2 2 0 Glyoxalase-like domain zf-H2C2_2 PF13465.6 KFM58846.1 - 6.3e-133 427.9 138.5 3.6e-10 39.8 0.7 20.1 20 0 0 20 20 20 19 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58846.1 - 1e-84 274.5 172.0 6e-06 26.4 2.3 19.1 19 0 0 19 19 19 19 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58846.1 - 3.4e-62 201.7 162.2 0.00037 21.1 1.0 19.2 19 0 0 19 19 19 19 C2H2-type zinc finger zf-met PF12874.7 KFM58846.1 - 2.1e-34 116.9 151.1 0.0041 17.5 0.9 19.3 19 0 0 19 19 19 16 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM58846.1 - 2e-20 72.3 153.9 0.0075 16.3 2.1 20.6 20 0 0 20 20 20 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM58846.1 - 4.5e-19 68.2 129.8 0.058 13.7 0.5 19.3 19 0 0 19 19 19 12 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM58846.1 - 1.1e-18 66.7 107.2 0.014 15.2 0.4 18.4 19 0 0 19 19 19 12 C2H2-type zinc-finger domain BolA PF01722.18 KFM58846.1 - 1.2e-05 25.5 39.1 2.3 8.6 3.4 10.1 2 2 5 7 7 7 2 BolA-like protein ADK_lid PF05191.14 KFM58846.1 - 0.00016 21.6 75.7 0.057 13.4 1.1 11.4 7 3 6 13 13 13 6 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM58846.1 - 0.00023 21.0 81.4 7.7 6.5 0.1 18.1 19 0 0 19 19 19 1 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM58846.1 - 0.00039 20.4 73.0 1.1 9.4 0.6 17.5 19 0 0 19 19 19 2 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 KFM58846.1 - 0.014 15.2 2.1 0.014 15.2 2.1 14.4 16 0 0 16 16 14 0 zinc-finger C2H2-type GAGA PF09237.11 KFM58846.1 - 0.033 14.0 33.7 5.3 6.9 0.1 9.8 6 4 6 12 12 12 0 GAGA factor DUF4825 PF16107.5 KFM58846.1 - 0.085 13.0 0.0 35 4.6 0.0 4.4 6 0 0 6 6 5 0 Domain of unknown function (DUF4825) zf-RRPl_C4 PF17026.5 KFM58846.1 - 0.25 11.5 84.9 0.13 12.3 1.8 8.6 1 1 9 10 10 10 0 Putative ribonucleoprotein zinc-finger pf C4 type FYVE PF01363.21 KFM58846.1 - 0.65 10.2 111.0 0.17 12.0 5.8 10.8 2 2 12 14 14 13 0 FYVE zinc finger DUF2256 PF10013.9 KFM58846.1 - 3.7 7.8 76.3 16 5.7 0.2 17.2 19 0 0 19 19 19 0 Uncharacterized protein conserved in bacteria (DUF2256) Tox-HNH-HHH PF15637.6 KFM58846.1 - 4.1 7.6 16.5 18 5.5 0.1 6.7 3 2 5 9 9 9 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf_UBZ PF18439.1 KFM58846.1 - 4.9 6.8 87.2 3.1 7.5 0.1 17.4 19 0 0 19 19 19 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM58846.1 - 7.4 7.0 129.4 0.58 10.5 1.3 16.2 1 1 13 15 15 14 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM58848.1 - 2.8e-85 277.2 71.5 2.3e-09 37.2 0.6 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58848.1 - 4.1e-59 193.9 92.7 7.4e-07 29.3 0.7 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58848.1 - 1.2e-41 137.7 85.5 0.00042 20.9 0.5 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM58848.1 - 2.5e-29 100.8 90.7 0.00094 19.5 0.4 11.6 12 0 0 12 12 11 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM58848.1 - 1.3e-21 76.0 70.2 0.004 17.1 1.1 11.7 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM58848.1 - 6.6e-17 61.3 70.4 0.012 15.8 1.0 11.5 11 0 0 11 11 11 9 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM58848.1 - 3.8e-11 42.5 55.8 0.033 13.9 0.1 11.3 11 0 0 11 11 11 7 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM58848.1 - 1.6e-08 34.2 52.6 0.13 12.2 0.1 11.5 11 1 0 11 11 11 3 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM58848.1 - 5.7e-08 32.6 32.6 0.1 12.6 0.4 6.9 3 1 3 6 6 6 5 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KFM58848.1 - 5e-07 29.7 51.0 0.84 9.7 0.1 11.8 7 2 5 12 12 12 3 Sec23/Sec24 zinc finger DUF2256 PF10013.9 KFM58848.1 - 7.4e-07 29.2 37.2 2.8 8.1 0.1 11.0 11 0 0 11 11 11 1 Uncharacterized protein conserved in bacteria (DUF2256) Tox-HNH-HHH PF15637.6 KFM58848.1 - 1.5e-06 28.3 4.9 0.92 9.7 0.1 4.0 1 1 1 3 3 3 3 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf_UBZ PF18439.1 KFM58848.1 - 0.00015 21.3 47.2 4.6 6.9 0.1 11.1 11 0 0 11 11 11 2 Ubiquitin-Binding Zinc Finger DUF4825 PF16107.5 KFM58848.1 - 0.0012 18.9 0.0 1.4 9.1 0.0 3.5 2 1 3 5 5 5 1 Domain of unknown function (DUF4825) BolA PF01722.18 KFM58848.1 - 0.0025 18.1 17.8 0.54 10.6 1.6 5.9 1 1 4 6 6 6 1 BolA-like protein FYVE PF01363.21 KFM58848.1 - 0.0026 17.9 62.6 0.021 15.0 12.1 6.5 2 2 2 5 5 4 1 FYVE zinc finger HNH_5 PF14279.6 KFM58848.1 - 0.0086 15.9 52.2 0.2 11.5 1.4 9.8 7 4 2 9 9 9 3 HNH endonuclease zf-DBF PF07535.12 KFM58848.1 - 0.015 15.4 52.5 9.2 6.5 0.1 10.4 11 0 0 11 11 10 0 DBF zinc finger zf-C2H2_3rep PF18868.1 KFM58848.1 - 0.045 14.4 43.9 4.3 8.0 1.1 9.2 5 3 3 8 8 8 0 Zinc finger C2H2-type, 3 repeats zf-RRPl_C4 PF17026.5 KFM58848.1 - 0.22 11.6 49.9 0.69 10.0 3.2 5.3 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFM58848.1 - 0.32 11.8 47.1 2.3 9.0 2.8 6.1 1 1 7 8 8 8 0 zinc-ribbon family GAGA PF09237.11 KFM58848.1 - 0.6 10.0 26.0 1.2 9.0 0.3 6.5 2 2 5 7 7 7 0 GAGA factor YyzF PF14116.6 KFM58848.1 - 0.86 9.7 33.2 45 4.2 0.1 10.2 11 0 0 11 11 11 0 YyzF-like protein C5HCH PF17982.1 KFM58848.1 - 0.95 9.7 60.0 3.3 7.9 1.2 10.6 6 5 5 11 11 11 0 NSD Cys-His rich domain zf-MYST PF17772.1 KFM58848.1 - 3.3 7.4 56.1 0.38 10.4 0.4 11.0 6 5 6 12 12 12 0 MYST family zinc finger domain zf-C2H2_11 PF16622.5 KFM58848.1 - 5.3 6.9 53.8 0.44 10.3 0.2 9.7 11 0 0 11 11 11 0 zinc-finger C2H2-type DOT1 PF08123.13 KFM58849.1 - 0.09 12.3 0.1 0.099 12.2 0.1 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 zf-H2C2_2 PF13465.6 KFM58850.1 - 2e-110 356.8 101.2 1e-07 32.0 0.8 17.1 17 0 0 17 17 17 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM58850.1 - 6.8e-70 227.8 132.1 8.3e-06 26.0 1.4 16.1 16 0 0 16 16 16 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM58850.1 - 5e-50 163.8 125.1 0.00064 20.3 0.9 16.0 16 0 0 16 16 16 15 C2H2-type zinc finger zf-met PF12874.7 KFM58850.1 - 2.6e-28 97.6 117.8 0.0054 17.1 0.9 16.6 15 1 1 16 16 16 14 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM58850.1 - 8.6e-23 79.8 81.5 0.031 14.0 0.9 15.4 15 0 0 15 15 15 12 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM58850.1 - 1.6e-21 75.8 105.5 0.0024 17.8 0.6 16.1 16 0 0 16 16 16 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM58850.1 - 1.3e-18 66.7 87.2 0.007 16.6 0.8 16.1 16 0 0 16 16 16 9 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM58850.1 - 3.9e-13 49.1 39.9 0.088 12.8 0.7 9.4 7 3 0 8 8 8 7 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM58850.1 - 9.7e-09 34.9 62.1 0.53 10.2 0.9 15.2 16 0 0 16 16 16 5 zinc-finger of a C2HC-type FYVE PF01363.21 KFM58850.1 - 1.6e-07 31.3 76.1 0.42 10.8 12.4 8.8 1 1 8 9 9 9 6 FYVE zinc finger Tox-HNH-HHH PF15637.6 KFM58850.1 - 8e-06 26.0 9.8 2.3 8.4 0.1 5.9 1 1 7 9 9 9 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF3396 PF11876.8 KFM58850.1 - 2.6e-05 23.8 0.0 20 4.6 0.0 6.1 2 2 6 8 8 8 0 Protein of unknown function (DUF3396) DUF2039 PF10217.9 KFM58850.1 - 7.1e-05 23.1 49.7 0.014 15.7 5.3 6.9 1 1 7 8 8 8 3 Uncharacterized conserved protein (DUF2039) DUF2256 PF10013.9 KFM58850.1 - 0.0004 20.5 53.9 6.7 6.9 0.3 14.5 16 0 0 16 16 15 1 Uncharacterized protein conserved in bacteria (DUF2256) Flag1_repress PF03614.13 KFM58850.1 - 0.00074 19.4 7.6 0.54 10.0 0.0 4.9 1 1 3 5 5 5 1 Repressor of phase-1 flagellin YyzF PF14116.6 KFM58850.1 - 0.0022 18.0 42.0 25 5.0 0.6 13.8 15 0 0 15 15 15 0 YyzF-like protein zf-Sec23_Sec24 PF04810.15 KFM58850.1 - 0.011 15.7 55.4 5.3 7.2 0.1 13.5 10 3 4 14 14 14 0 Sec23/Sec24 zinc finger zf-CHCC PF10276.9 KFM58850.1 - 0.013 15.6 18.8 79 3.4 0.0 11.2 14 0 0 14 14 14 0 Zinc-finger domain HNH_5 PF14279.6 KFM58850.1 - 0.022 14.6 70.8 2.2 8.2 0.7 12.8 6 5 5 11 11 11 0 HNH endonuclease BolA PF01722.18 KFM58850.1 - 0.026 14.8 22.5 0.14 12.5 0.6 7.5 2 2 6 8 8 8 0 BolA-like protein zf-RRPl_C4 PF17026.5 KFM58850.1 - 0.038 14.1 56.7 0.57 10.3 3.0 7.0 1 1 6 7 7 7 0 Putative ribonucleoprotein zinc-finger pf C4 type NAD_kinase PF01513.21 KFM58850.1 - 0.047 12.9 0.2 22 4.1 0.0 3.4 2 2 0 3 3 3 0 ATP-NAD kinase Mga PF05043.13 KFM58850.1 - 0.24 12.0 4.6 25 5.5 0.1 4.1 4 1 0 5 5 4 0 Mga helix-turn-helix domain zinc_ribbon_15 PF17032.5 KFM58850.1 - 6.3 7.6 56.6 7 7.5 1.1 8.2 1 1 10 11 11 11 0 zinc-ribbon family Y_phosphatase PF00102.27 KFM58851.1 - 1e-12 48.1 0.0 1e-12 48.1 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 KFM58852.1 - 7.1e-51 173.0 0.7 3.2e-50 170.9 0.1 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DDE_Tnp_1_7 PF13843.6 KFM58854.1 - 0.082 12.2 0.0 0.082 12.2 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 rve PF00665.26 KFM58855.1 - 6.9e-09 35.9 0.0 9.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KFM58855.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain EIIA-man PF03610.16 KFM58855.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 1 1 2 2 2 0 PTS system fructose IIA component CM1 PF03026.15 KFM58858.1 - 0.044 13.1 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Influenza C virus M1 protein HTH_Tnp_Tc3_2 PF01498.18 KFM58859.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58859.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58859.1 - 1.9e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58859.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58859.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF659 PF04937.15 KFM58860.1 - 0.00018 21.4 0.2 0.00061 19.7 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM58860.1 - 0.00028 20.6 0.3 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-BED PF02892.15 KFM58860.1 - 0.0053 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 BED zinc finger DDE_3 PF13358.6 KFM58861.1 - 9.1e-11 41.7 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.18 KFM58862.1 - 2.1e-17 62.7 0.1 5.1e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM58862.1 - 4.1e-06 26.6 0.0 8.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM58862.1 - 2e-05 25.1 2.5 0.00015 22.3 2.3 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 KFM58862.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding BTG PF07742.12 KFM58863.1 - 1.9e-37 127.7 0.0 3.3e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 BTG family DUF2574 PF10836.8 KFM58863.1 - 0.19 11.6 0.8 0.44 10.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) Herpes_DNAp_acc PF04929.12 KFM58863.1 - 0.33 9.9 5.3 0.56 9.1 5.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Thioredoxin PF00085.20 KFM58864.1 - 1.4e-08 34.6 0.0 4.2e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFM58864.1 - 0.012 15.0 1.1 0.033 13.5 1.0 1.9 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family TraF PF13728.6 KFM58864.1 - 0.18 11.6 0.2 0.49 10.2 0.2 1.7 1 1 1 2 2 2 0 F plasmid transfer operon protein PRELI PF04707.14 KFM58865.1 - 4.5e-30 104.5 0.2 5.7e-30 104.2 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family T-box PF00907.22 KFM58866.1 - 3.4e-52 177.4 0.0 5.1e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 T-box HlyU PF10115.9 KFM58867.1 - 0.1 12.6 0.1 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 Transcriptional activator HlyU Patched PF02460.18 KFM58868.1 - 3.7e-112 376.0 9.0 4.6e-112 375.6 9.0 1.0 1 0 0 1 1 1 1 Patched family ATG27 PF09451.10 KFM58868.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 ACR_tran PF00873.19 KFM58868.1 - 0.78 7.3 8.2 1 6.9 8.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 KFM58868.1 - 9.9 5.5 16.5 32 3.8 16.5 1.8 1 1 0 1 1 1 0 Protein export membrane protein Patched PF02460.18 KFM58869.1 - 3.9e-31 108.0 1.0 4.2e-31 107.9 1.0 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFM58869.1 - 0.0025 17.7 0.3 0.0025 17.7 0.3 2.1 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation DUF3040 PF11239.8 KFM58869.1 - 0.12 12.6 1.2 0.21 11.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Glug PF07581.12 KFM58869.1 - 4 8.1 7.1 0.3 11.6 1.6 2.0 2 0 0 2 2 2 0 The GLUG motif FIST_C PF10442.9 KFM58871.1 - 1.2e-10 41.5 0.4 3.7e-10 39.9 0.0 2.0 2 1 0 2 2 2 1 FIST C domain F-box PF00646.33 KFM58871.1 - 5.9e-07 29.2 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFM58871.1 - 9.5e-06 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like FIST PF08495.10 KFM58871.1 - 3.8e-05 23.8 0.0 0.1 12.6 0.0 2.7 3 0 0 3 3 3 2 FIST N domain HTH_Tnp_Tc3_2 PF01498.18 KFM58872.1 - 6.3e-18 64.8 1.9 9.9e-18 64.2 1.9 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58872.1 - 1.5e-16 60.4 0.0 1.1e-15 57.7 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM58872.1 - 0.23 12.1 2.0 1.2 9.8 0.2 2.4 1 1 1 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.6 KFM58874.1 - 2e-05 24.4 0.1 2.9e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58875.1 - 5.6e-16 58.6 3.5 6.2e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58875.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58875.1 - 3.1e-07 30.0 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58875.1 - 0.0029 17.3 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM58876.1 - 8.5e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58876.1 - 2.2e-15 56.7 0.1 6.4e-15 55.2 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM58876.1 - 0.00042 20.9 1.6 0.00042 20.9 1.6 3.1 3 1 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM58876.1 - 0.034 14.2 0.3 0.034 14.2 0.3 2.7 3 0 0 3 3 3 0 Winged helix-turn helix HTH_23 PF13384.6 KFM58876.1 - 0.042 13.6 4.3 0.13 12.1 0.0 3.3 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM58877.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58877.1 - 2.4e-12 46.9 0.0 3.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58878.1 - 4.6e-16 58.8 1.5 3.5e-15 56.0 0.7 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58878.1 - 1.5e-07 31.2 0.0 3.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM58878.1 - 0.21 12.2 2.3 0.26 11.9 0.8 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Homeodomain PF00046.29 KFM58880.1 - 5.8e-22 77.3 4.0 1.2e-21 76.3 4.0 1.5 1 0 0 1 1 1 1 Homeodomain DUF447 PF04289.12 KFM58880.1 - 0.069 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) SatD PF16264.5 KFM58880.1 - 0.14 11.7 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 SatD family (SatD) QWRF PF04484.12 KFM58880.1 - 2.3 7.9 8.4 3.7 7.2 8.4 1.3 1 0 0 1 1 1 0 QWRF family HTH_Tnp_Tc3_2 PF01498.18 KFM58881.1 - 1.8e-19 69.8 3.6 5.7e-19 68.1 2.1 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58881.1 - 3.8e-16 59.1 0.0 2.3e-15 56.6 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM58881.1 - 2.1e-07 30.9 0.4 0.00014 21.9 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM58881.1 - 3.6e-07 30.7 2.0 3.6e-07 30.7 2.0 2.7 3 0 0 3 3 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM58881.1 - 8.1e-07 29.1 2.3 7.6e-05 22.8 0.2 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58881.1 - 1.7e-06 27.6 3.4 2.5e-05 23.9 0.0 3.0 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM58881.1 - 3.7e-05 23.7 5.0 4e-05 23.6 0.1 2.8 3 0 0 3 3 3 1 Winged helix-turn helix MarR_2 PF12802.7 KFM58881.1 - 0.00011 22.0 0.6 0.0017 18.2 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM58881.1 - 0.0011 18.9 0.3 0.016 15.1 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM58881.1 - 0.02 14.5 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM58881.1 - 0.054 13.6 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1204 PF06721.11 KFM58881.1 - 0.12 11.8 4.9 0.2 11.1 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) HTH_30 PF13556.6 KFM58881.1 - 0.29 11.0 3.9 1.4 8.7 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM58881.1 - 1.1 8.7 3.6 7.1 6.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 L_HMGIC_fpl PF10242.9 KFM58882.1 - 1.9e-23 83.6 1.6 2.3e-23 83.3 1.6 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein CRPA PF05745.11 KFM58882.1 - 0.15 12.1 1.9 0.25 11.3 1.9 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) OTU PF02338.19 KFM58883.1 - 9.7e-32 110.1 0.0 1.9e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease AnkUBD PF18418.1 KFM58883.1 - 1.2e-23 83.0 0.0 2.5e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin ubiquitin-binding domain zf-RanBP PF00641.18 KFM58883.1 - 8.7e-13 47.3 41.5 9.7e-05 21.6 7.5 3.8 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 KFM58883.1 - 6 7.0 17.3 0.46 10.5 7.7 2.8 1 1 2 3 3 3 0 Double zinc ribbon DUF4187 PF13821.6 KFM58885.1 - 7.4 6.4 10.9 0.28 11.0 4.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4187) Ras PF00071.22 KFM58887.1 - 3.5e-35 121.0 0.1 4.2e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM58887.1 - 4.2e-24 85.1 0.0 6.9e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM58887.1 - 9.5e-12 44.7 0.0 1.2e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM58887.1 - 2.3e-10 40.2 0.1 2.8e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFM58887.1 - 1.6e-08 34.6 0.0 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFM58887.1 - 5.9e-07 29.6 0.0 9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFM58887.1 - 0.0032 16.9 0.0 0.0068 15.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KFM58887.1 - 0.019 14.7 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM58887.1 - 0.026 14.8 0.0 0.065 13.5 0.0 1.7 2 1 0 2 2 2 0 AAA domain ABC_membrane_2 PF06472.15 KFM58887.1 - 0.084 12.3 0.2 0.11 11.8 0.2 1.4 1 1 0 1 1 1 0 ABC transporter transmembrane region 2 Epimerase PF01370.21 KFM58888.1 - 3.3e-35 121.7 0.0 4e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM58888.1 - 4.4e-28 98.6 0.0 6.3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFM58888.1 - 3.5e-19 68.9 0.0 4.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFM58888.1 - 7.5e-19 67.9 0.0 8.9e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFM58888.1 - 1.2e-10 41.1 0.0 3.7e-10 39.4 0.0 1.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFM58888.1 - 4.3e-09 35.9 1.5 1.3e-05 24.5 0.1 2.6 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KFM58888.1 - 5.1e-07 29.8 0.0 8.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFM58888.1 - 5.4e-05 23.5 0.0 0.00018 21.7 0.0 1.9 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KFM58888.1 - 7.5e-05 22.4 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KFM58888.1 - 0.00012 21.6 0.0 0.00039 19.9 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFM58888.1 - 0.027 14.0 0.0 0.083 12.5 0.0 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.10 KFM58888.1 - 0.14 12.1 0.1 3.4 7.6 0.1 2.3 2 0 0 2 2 2 0 KR domain PH PF00169.29 KFM58889.1 - 5.3e-06 26.9 0.0 1.6e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 PH domain IRS PF02174.17 KFM58889.1 - 0.0091 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) zf-C2H2_4 PF13894.6 KFM58891.1 - 4.2e-05 24.0 42.9 0.011 16.5 2.3 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM58891.1 - 0.00025 21.3 40.2 0.0077 16.6 2.4 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM58891.1 - 0.0032 17.7 2.2 0.0032 17.7 2.2 5.0 5 1 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM58891.1 - 0.016 15.6 0.8 0.016 15.6 0.8 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type DUF4860 PF16152.5 KFM58891.1 - 4 7.4 5.7 9 6.2 0.4 2.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4860) Hva1_TUDOR PF11160.8 KFM58891.1 - 6.8 6.9 9.6 3.1 8.0 1.3 3.1 1 1 2 3 3 3 0 Hypervirulence associated proteins TUDOR domain Complex1_51K PF01512.17 KFM58892.1 - 6.9e-46 155.9 0.0 9e-46 155.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit DUF3568 PF12092.8 KFM58892.1 - 0.054 13.6 0.5 0.088 12.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) GCS PF03074.16 KFM58893.1 - 1.5e-36 126.6 0.1 1.8e-36 126.3 0.1 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Mrpl_C PF18502.1 KFM58893.1 - 0.09 13.1 0.1 0.23 11.8 0.0 1.7 1 1 1 2 2 2 0 54S ribosomal protein L8 C-terminal domain GCS PF03074.16 KFM58894.1 - 3.8e-32 112.1 0.3 4.1e-32 112.0 0.3 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS PF03074.16 KFM58895.1 - 4.6e-18 65.7 0.9 6e-18 65.4 0.9 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase MttA_Hcf106 PF02416.16 KFM58896.1 - 0.17 11.3 0.3 0.31 10.4 0.1 1.6 2 0 0 2 2 2 0 mttA/Hcf106 family Metallophos PF00149.28 KFM58898.1 - 3.6e-09 37.4 0.0 4.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFM58898.1 - 0.00033 21.0 0.3 0.001 19.5 0.3 1.8 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF5378 PF17349.2 KFM58898.1 - 0.016 14.5 0.0 0.034 13.5 0.0 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5378) 23S_rRNA_IVP PF05635.11 KFM58898.1 - 0.02 15.2 1.1 0.03 14.6 1.1 1.2 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein DDE_Tnp_4 PF13359.6 KFM58899.1 - 0.00061 19.5 0.0 0.00061 19.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Ubiquitin_3 PF14836.6 KFM58899.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin-like domain Zona_pellucida PF00100.23 KFM58900.1 - 5e-13 49.4 1.2 5.8e-13 49.2 0.1 1.6 2 0 0 2 2 2 1 Zona pellucida-like domain TIG_plexin PF17960.1 KFM58901.1 - 8.8e-21 73.7 0.1 2.4e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 TIG domain TIG_2 PF18020.1 KFM58901.1 - 2.7e-10 40.7 0.3 5.5e-10 39.7 0.3 1.5 1 0 0 1 1 1 1 TIG domain found in plexin PSI PF01437.25 KFM58901.1 - 6.1e-06 26.7 15.0 1e-05 25.9 15.0 1.4 1 0 0 1 1 1 1 Plexin repeat TIG PF01833.24 KFM58902.1 - 2e-09 37.4 0.0 2.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 IPT/TIG domain Plexin_cytopl PF08337.12 KFM58903.1 - 1.7e-86 291.1 2.8 2.2e-86 290.7 2.8 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFM58903.1 - 4.1e-11 42.8 0.2 5.8e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 IPT/TIG domain Plexin_cytopl PF08337.12 KFM58904.1 - 6.2e-107 358.6 0.1 7.3e-107 358.3 0.1 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Syntaxin PF00804.25 KFM58905.1 - 4.7e-31 108.0 13.6 6.4e-31 107.6 13.6 1.2 1 0 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 KFM58905.1 - 6.1e-06 26.5 3.1 6.1e-06 26.5 3.1 2.6 1 1 1 2 2 2 1 Syntaxin-like protein ETC_C1_NDUFA5 PF04716.14 KFM58905.1 - 0.025 14.4 2.1 0.043 13.6 1.0 2.1 2 0 0 2 2 2 0 ETC complex I subunit conserved region V-SNARE PF05008.15 KFM58905.1 - 0.051 14.0 0.2 0.051 14.0 0.2 3.9 2 2 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus SNARE PF05739.19 KFM58905.1 - 0.12 12.4 0.3 0.12 12.4 0.3 2.7 3 0 0 3 3 3 0 SNARE domain NOC3p PF07540.11 KFM58905.1 - 0.28 11.7 3.4 0.24 11.9 1.2 2.1 2 1 0 2 2 2 0 Nucleolar complex-associated protein PAH PF02671.21 KFM58905.1 - 0.33 11.1 4.6 2.7 8.2 4.6 2.4 1 1 0 1 1 1 0 Paired amphipathic helix repeat CLZ PF16526.5 KFM58905.1 - 0.37 11.2 13.2 0.35 11.3 2.3 3.8 3 1 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAUS6_N PF14661.6 KFM58905.1 - 0.91 9.1 9.2 1.6 8.3 8.8 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SlyX PF04102.12 KFM58905.1 - 9.7 6.9 9.6 3.1 8.5 0.1 3.9 2 2 2 4 4 4 0 SlyX Homeobox_KN PF05920.11 KFM58906.1 - 3.8e-18 65.1 0.7 7.4e-18 64.2 0.7 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFM58906.1 - 2.4e-08 33.7 1.7 5.3e-08 32.6 1.7 1.5 1 0 0 1 1 1 1 Homeodomain CBM_14 PF01607.24 KFM58909.1 - 9.4e-14 51.3 1.2 9.8e-14 51.3 1.2 1.0 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain THAP PF05485.12 KFM58910.1 - 4e-14 53.3 0.6 4e-14 53.3 0.6 2.5 2 1 0 2 2 1 1 THAP domain Shugoshin_N PF07558.11 KFM58910.1 - 0.0044 16.9 6.6 2.2 8.2 0.5 3.4 1 1 2 3 3 3 2 Shugoshin N-terminal coiled-coil region DUF812 PF05667.11 KFM58910.1 - 0.023 13.6 23.1 0.03 13.2 23.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Mto2_bdg PF12808.7 KFM58910.1 - 0.029 14.7 6.8 0.64 10.3 1.2 3.3 1 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Macoilin PF09726.9 KFM58910.1 - 0.13 10.8 25.1 0.16 10.5 25.1 1.1 1 0 0 1 1 1 0 Macoilin family Cep57_CLD_2 PF14197.6 KFM58910.1 - 0.51 10.5 13.0 2.1e+02 2.1 12.8 2.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Viral_P18 PF04521.13 KFM58910.1 - 3.8 7.3 7.1 0.92 9.3 2.1 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 KFM58910.1 - 4.4 7.8 26.4 14 6.2 3.3 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KFM58910.1 - 5.4 7.5 8.2 26 5.3 0.7 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KFM58910.1 - 6.7 6.6 12.0 3.3 7.5 3.4 2.6 1 1 1 2 2 2 0 Septum formation initiator CytochromB561_N PF09786.9 KFM58910.1 - 8 5.3 18.2 9.6 5.1 18.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SlyX PF04102.12 KFM58910.1 - 8.3 7.1 8.7 88 3.8 1.0 3.1 1 1 1 2 2 2 0 SlyX Trypsin PF00089.26 KFM58911.1 - 4e-53 180.5 0.0 4.7e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM58911.1 - 3.8e-06 27.9 0.1 6.2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM58911.1 - 0.036 14.4 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) HTH_Tnp_Tc3_2 PF01498.18 KFM58912.1 - 1.3e-16 60.6 0.9 2.5e-16 59.7 0.9 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM58912.1 - 8e-06 26.4 1.6 8e-06 26.4 1.6 2.3 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM58912.1 - 0.0047 16.8 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 MarR family HTH_3 PF01381.22 KFM58912.1 - 0.038 14.1 0.7 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix PAX PF00292.18 KFM58912.1 - 0.044 13.7 0.0 0.08 12.9 0.0 1.4 1 1 0 1 1 1 0 'Paired box' domain HTH_Crp_2 PF13545.6 KFM58912.1 - 0.078 13.0 0.9 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KFM58912.1 - 0.21 11.4 1.2 4.7 7.1 0.1 2.6 2 0 0 2 2 2 0 Homeodomain-like domain Nepo_coat_C PF03688.14 KFM58913.1 - 0.072 12.9 0.0 0.088 12.7 0.0 1.1 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM58914.1 - 7.8e-13 48.5 0.8 1.8e-12 47.3 0.7 1.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58914.1 - 0.00047 19.9 0.0 0.0052 16.6 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58914.1 - 0.00058 19.6 0.1 0.0082 15.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM58914.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Tc3 transposase HTH_23 PF13384.6 KFM58914.1 - 0.0043 16.8 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM58914.1 - 0.006 16.7 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_48 PF17906.1 KFM58915.1 - 4.2e-16 58.8 0.4 8.9e-16 57.8 0.4 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Transposase_1 PF01359.18 KFM58915.1 - 1.5e-15 56.8 0.1 3.8e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_32 PF13565.6 KFM58915.1 - 2.8e-05 24.7 0.0 9.9e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 KFM58915.1 - 7.1e-05 22.6 0.0 0.00016 21.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_50 PF18024.1 KFM58915.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KFM58915.1 - 0.0015 18.6 0.1 0.76 10.0 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM58915.1 - 0.0032 17.7 0.1 0.0066 16.7 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_24 PF13412.6 KFM58915.1 - 0.022 14.3 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 KFM58915.1 - 0.028 14.3 0.2 0.065 13.1 0.1 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 KFM58915.1 - 0.034 14.1 0.2 0.085 12.8 0.2 1.6 1 0 0 1 1 1 0 HTH domain HTH_10 PF04967.12 KFM58915.1 - 0.042 13.6 0.1 0.096 12.5 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain TrmB PF01978.19 KFM58915.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB BTB_2 PF02214.22 KFM58916.1 - 7.1e-21 74.4 0.0 9.7e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 KFM58917.1 - 6.1e-48 163.2 15.3 7.4e-48 162.9 15.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFM58917.1 - 7.3e-14 51.5 5.4 7.3e-14 51.5 5.4 3.1 3 1 0 3 3 3 1 Ion channel Sigma_reg_N PF13800.6 KFM58917.1 - 0.0058 16.9 4.3 3.1 8.2 0.1 3.6 3 0 0 3 3 3 2 Sigma factor regulator N-terminal DUF423 PF04241.15 KFM58917.1 - 0.11 12.7 0.5 0.59 10.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF423) PKD_channel PF08016.12 KFM58917.1 - 0.15 10.7 10.4 0.041 12.6 5.1 2.1 1 1 1 2 2 2 0 Polycystin cation channel Transposase_1 PF01359.18 KFM58918.1 - 4.2e-24 84.2 0.7 7.5e-24 83.4 0.7 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM58918.1 - 6.4e-07 29.2 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Argos PF11581.8 KFM58920.1 - 0.027 14.5 4.2 0.025 14.6 2.5 1.7 1 1 1 2 2 2 0 Antagonist of EGFR signalling, Argos UCH PF00443.29 KFM58922.1 - 3.4e-43 148.0 0.0 4.3e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KFM58922.1 - 7e-22 77.0 0.1 3.4e-12 46.0 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 KFM58922.1 - 1.7e-17 63.5 0.2 4.7e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFM58922.1 - 9e-14 51.8 0.2 1.4e-10 41.2 0.2 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KFM58922.1 - 0.00083 19.1 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain Phage_30_8 PF06019.11 KFM58923.1 - 0.15 12.0 0.0 0.15 12.0 0.0 1.0 1 0 0 1 1 1 0 Phage GP30.8 protein VWA_2 PF13519.6 KFM58924.1 - 2.9e-12 47.2 0.0 3.5e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KFM58924.1 - 0.0028 17.9 0.0 0.0051 17.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Exostosin PF03016.15 KFM58926.1 - 2.4e-32 112.3 0.0 5.7e-32 111.1 0.0 1.5 1 1 0 1 1 1 1 Exostosin family DMPK_coil PF08826.10 KFM58926.1 - 0.013 15.5 0.9 0.033 14.3 0.9 1.7 1 0 0 1 1 1 0 DMPK coiled coil domain like CLZ PF16526.5 KFM58926.1 - 0.045 14.1 1.4 0.1 13.0 1.4 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PI-PLC-C1 PF16670.5 KFM58926.1 - 0.048 12.7 0.0 4.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent HAUS-augmin3 PF14932.6 KFM58926.1 - 0.095 12.3 0.8 0.16 11.5 0.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 KFM58926.1 - 0.097 13.3 0.6 0.2 12.3 0.6 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF641 PF04859.12 KFM58926.1 - 0.13 12.6 3.9 0.22 11.9 3.9 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1640 PF07798.11 KFM58926.1 - 0.36 10.9 2.7 0.7 9.9 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) GAS PF13851.6 KFM58926.1 - 0.38 10.1 5.2 0.67 9.3 5.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HIP1_clath_bdg PF16515.5 KFM58926.1 - 0.38 11.4 6.0 0.77 10.4 6.0 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 KFM58926.1 - 0.66 10.6 3.8 1.4 9.6 3.8 1.5 1 0 0 1 1 1 0 SlyX ZapB PF06005.12 KFM58926.1 - 1 9.9 8.1 4.2 7.9 7.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Ribosomal_L38e PF01781.18 KFM58927.1 - 0.045 13.9 1.0 0.052 13.7 1.0 1.2 1 0 0 1 1 1 0 Ribosomal L38e protein family Transposase_1 PF01359.18 KFM58930.1 - 6.3e-23 80.4 0.6 1.4e-22 79.3 0.6 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM58930.1 - 8.3e-14 51.4 0.3 1.7e-13 50.4 0.3 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_50 PF18024.1 KFM58930.1 - 8.8e-06 25.2 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM58930.1 - 1.6e-05 25.4 0.0 4.8e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM58930.1 - 0.0012 18.9 0.1 1.6 8.9 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM58930.1 - 0.0026 18.0 0.5 0.016 15.5 0.1 2.1 2 0 0 2 2 2 1 Transposase HTH_11 PF08279.12 KFM58930.1 - 0.0029 17.5 0.1 0.014 15.4 0.1 2.0 2 0 0 2 2 2 1 HTH domain GerE PF00196.19 KFM58930.1 - 0.014 14.9 1.0 0.092 12.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_10 PF04967.12 KFM58930.1 - 0.033 14.0 0.4 0.077 12.8 0.0 1.7 2 0 0 2 2 2 0 HTH DNA binding domain M60-like_N PF17291.2 KFM58930.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases HTH_38 PF13936.6 KFM58930.1 - 0.058 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 KFM58930.1 - 0.06 12.9 0.2 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM58930.1 - 0.06 13.2 0.1 0.54 10.1 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Peptidase_C2 PF00648.21 KFM58931.1 - 1.5e-42 145.7 0.2 2.3e-42 145.1 0.2 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MTCP1 PF08991.10 KFM58932.1 - 3.2e-10 40.1 6.9 4.6e-10 39.6 6.9 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KFM58932.1 - 0.035 14.2 4.5 0.066 13.4 4.5 1.5 1 0 0 1 1 1 0 CHCH domain DDE_3 PF13358.6 KFM58933.1 - 1.1e-16 60.9 0.1 1.2e-15 57.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58933.1 - 8e-16 58.1 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM58933.1 - 0.00079 20.0 1.5 0.00079 20.0 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM58933.1 - 0.0025 17.6 0.1 0.13 12.1 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM58933.1 - 0.017 15.2 0.1 0.071 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM58933.1 - 0.038 14.0 2.6 0.038 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix GILT PF03227.16 KFM58934.1 - 1.1e-32 112.4 0.3 2.5e-32 111.3 0.3 1.6 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF4807 PF16065.5 KFM58935.1 - 2.4e-36 124.2 1.2 3.5e-36 123.7 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4807) DDE_3 PF13358.6 KFM58936.1 - 1.5e-06 28.0 0.2 1.1e-05 25.2 0.1 2.4 2 1 0 2 2 2 1 DDE superfamily endonuclease Peptidase_C1_2 PF03051.15 KFM58937.1 - 1e-176 588.1 0.0 1.1e-176 587.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KFM58937.1 - 1e-07 32.3 0.5 0.0028 17.8 0.1 2.7 3 0 0 3 3 3 2 Papain family cysteine protease HTH_Tnp_Tc3_2 PF01498.18 KFM58939.1 - 3.9e-16 59.0 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58939.1 - 1.5e-13 50.7 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58939.1 - 7e-06 25.7 1.1 2.3e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Tetraspanin PF00335.20 KFM58941.1 - 4.8e-46 157.3 7.6 5.5e-46 157.1 7.6 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 KFM58941.1 - 0.00093 19.3 6.6 0.0036 17.4 5.5 2.0 2 0 0 2 2 2 1 CD20-like family Ac76 PF05814.11 KFM58941.1 - 0.09 12.8 2.8 0.18 11.8 2.8 1.5 1 0 0 1 1 1 0 Orf76 (Ac76) Phage_holin_3_6 PF07332.11 KFM58941.1 - 0.14 12.2 15.9 3.1 7.9 0.4 3.1 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2981 PF11200.8 KFM58941.1 - 0.53 10.0 2.8 0.69 9.6 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) HTH_Tnp_Tc3_2 PF01498.18 KFM58942.1 - 0.00096 19.4 1.1 0.0077 16.5 1.1 2.0 2 0 0 2 2 2 1 Transposase BrkDBD PF09607.10 KFM58943.1 - 1.9e-08 34.0 0.2 4.9e-08 32.6 0.2 1.7 1 1 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_Tc5 PF03221.16 KFM58943.1 - 2e-08 34.1 0.3 3.6e-08 33.3 0.3 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 KFM58943.1 - 0.00071 19.8 1.8 0.016 15.5 0.9 2.2 2 0 0 2 2 2 1 Transposase Endotoxin_N PF03945.14 KFM58943.1 - 0.087 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Phage_tail_APC PF16778.5 KFM58943.1 - 0.095 12.6 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone protein DDE_1 PF03184.19 KFM58944.1 - 1.7e-15 57.1 0.1 1.9e-15 57.0 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Stimulus_sens_1 PF13756.6 KFM58944.1 - 0.093 13.3 0.0 0.16 12.6 0.0 1.4 1 1 0 1 1 1 0 Stimulus-sensing domain HSCB_C PF07743.13 KFM58945.1 - 3.8e-16 59.3 0.3 4.6e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain Helicase_C PF00271.31 KFM58946.1 - 6e-23 81.3 0.0 1.7e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KFM58946.1 - 1.2e-18 67.1 9.7 3.3e-18 65.7 9.7 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain TcdB_N PF12918.7 KFM58946.1 - 0.018 15.3 0.7 0.062 13.6 0.7 1.9 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain DEAD PF00270.29 KFM58946.1 - 0.13 12.0 0.0 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase DEAD PF00270.29 KFM58947.1 - 1.6e-28 99.7 0.1 1.9e-28 99.4 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM58947.1 - 0.0016 18.5 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4371 PF14291.6 KFM58949.1 - 5.6e-10 39.3 0.1 2.2e-09 37.3 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM58949.1 - 0.0031 17.1 0.4 0.0031 17.1 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger C2H2-type HAUS4 PF14735.6 KFM58950.1 - 7.5e-26 91.3 7.8 1.3e-25 90.5 7.8 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 HTH_Tnp_Tc3_2 PF01498.18 KFM58952.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58952.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease BAF250_C PF12031.8 KFM58954.1 - 3.5e-111 370.6 1.0 3.5e-111 370.6 1.0 1.5 2 0 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 KFM58954.1 - 2.7e-16 60.0 0.0 6.3e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Retrotran_gag_2 PF14223.6 KFM58955.1 - 6.6e-40 136.0 2.6 1.2e-39 135.1 2.6 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 KFM58955.1 - 2.2e-22 79.4 0.0 9.7e-22 77.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 KFM58955.1 - 4.8e-11 42.4 1.5 4.8e-11 42.4 1.5 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain NDK PF00334.19 KFM58955.1 - 0.0043 17.1 0.0 0.61 10.1 0.0 2.6 2 0 0 2 2 2 1 Nucleoside diphosphate kinase zf-C2H2_10 PF16588.5 KFM58955.1 - 0.0049 16.6 5.7 0.016 15.0 5.7 1.9 1 0 0 1 1 1 1 C2H2 zinc-finger DUF4219 PF13961.6 KFM58955.1 - 0.017 14.8 0.1 0.044 13.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) TraY PF05509.11 KFM58955.1 - 0.042 13.9 0.3 0.11 12.5 0.3 1.8 1 0 0 1 1 1 0 TraY domain zf-CCHC_4 PF14392.6 KFM58955.1 - 0.14 11.9 1.7 0.36 10.6 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_3 PF14244.6 KFM58955.1 - 0.22 11.4 1.7 0.31 10.9 0.2 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Integrase_H2C2 PF17921.1 KFM58955.1 - 0.56 10.3 3.4 1.6 8.9 3.4 1.8 1 0 0 1 1 1 0 Integrase zinc binding domain PSI_integrin PF17205.3 KFM58955.1 - 1.4 8.7 15.0 5.4 6.9 4.6 3.1 2 0 0 2 2 2 0 Integrin plexin domain RVT_2 PF07727.14 KFM58956.1 - 3.1e-08 33.6 0.4 4.7e-08 33.0 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFM58956.1 - 0.00013 21.5 0.2 0.00026 20.6 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mga PF05043.13 KFM58956.1 - 0.012 16.1 1.3 2.4 8.8 0.3 2.5 2 0 0 2 2 2 0 Mga helix-turn-helix domain LAGLIDADG_WhiA PF14527.6 KFM58956.1 - 0.13 12.3 0.6 0.99 9.5 0.3 2.2 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain EMP24_GP25L PF01105.24 KFM58957.1 - 2.7e-42 144.8 0.1 3.1e-42 144.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GYD PF08734.11 KFM58957.1 - 0.067 13.2 0.1 0.92 9.5 0.1 2.3 2 1 0 2 2 2 0 GYD domain CABS1 PF15367.6 KFM58958.1 - 0.012 14.8 0.7 0.017 14.2 0.0 1.5 2 0 0 2 2 2 0 Calcium-binding and spermatid-specific protein 1 GCP5-Mod21 PF14609.6 KFM58958.1 - 0.34 9.2 1.2 0.46 8.8 1.2 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 HTH_Tnp_Tc3_2 PF01498.18 KFM58959.1 - 3.6e-16 59.2 3.4 5.4e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58959.1 - 2.7e-14 53.2 0.0 4.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58959.1 - 2.6e-07 30.3 0.2 6.8e-07 29.0 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58959.1 - 0.0023 17.7 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58959.1 - 1.9 9.2 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM58960.1 - 5.7e-16 58.5 2.2 5.7e-16 58.5 2.2 2.3 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM58960.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58960.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58960.1 - 0.0026 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58960.1 - 2.2 8.9 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DUF659 PF04937.15 KFM58961.1 - 0.00017 21.5 0.2 0.00059 19.7 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM58961.1 - 0.00027 20.7 0.3 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KFM58962.1 - 0.00019 21.4 0.2 0.00063 19.6 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM58962.1 - 0.00029 20.6 0.3 0.0012 18.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-BED PF02892.15 KFM58962.1 - 0.0054 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 BED zinc finger Transposase_1 PF01359.18 KFM58963.1 - 0.0003 20.5 0.0 0.00074 19.3 0.0 1.7 1 1 1 2 2 2 1 Transposase (partial DDE domain) BST2 PF16716.5 KFM58964.1 - 0.038 14.6 0.7 0.11 13.1 0.7 1.7 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 UPF0242 PF06785.11 KFM58964.1 - 0.042 14.0 1.6 0.071 13.2 1.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sina PF03145.16 KFM58964.1 - 0.77 9.7 12.3 1.2 9.0 12.3 1.4 1 0 0 1 1 1 0 Seven in absentia protein family Arf PF00025.21 KFM58966.1 - 6.5e-56 188.5 0.0 8e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFM58966.1 - 1.1e-12 48.2 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM58966.1 - 3.4e-12 46.3 0.0 4.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFM58966.1 - 7.4e-12 45.1 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFM58966.1 - 0.00011 21.5 0.1 0.0018 17.5 0.1 2.1 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFM58966.1 - 0.00032 20.8 0.0 0.00049 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM58966.1 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM58966.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Microvir_J PF04726.13 KFM58966.1 - 0.066 13.2 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Microvirus J protein 6PF2K PF01591.18 KFM58966.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DDE_3 PF13358.6 KFM58967.1 - 3e-14 53.0 0.1 2.5e-13 50.0 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58967.1 - 1.5e-10 41.2 1.0 2.8e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM58968.1 - 7.7e-16 58.1 6.5 1.2e-15 57.4 6.5 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM58968.1 - 0.00062 20.3 1.5 0.00062 20.3 1.5 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM58968.1 - 0.0018 18.0 0.2 0.049 13.4 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM58968.1 - 0.0068 16.5 0.2 0.022 14.9 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM58968.1 - 0.017 15.1 2.0 0.025 14.6 0.3 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM58968.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase LRR_8 PF13855.6 KFM58969.1 - 2e-12 46.7 9.7 2.1e-07 30.6 3.5 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM58969.1 - 3.7e-08 33.5 7.8 1.2e-06 28.8 4.4 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM58969.1 - 4.2e-05 23.5 3.5 1.5 9.6 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 KFM58969.1 - 0.0021 18.0 0.6 0.52 10.5 0.1 3.3 3 0 0 3 3 3 1 Leucine Rich repeat SPW PF03779.14 KFM58969.1 - 0.24 11.0 0.0 0.41 10.3 0.0 1.3 1 0 0 1 1 1 0 SPW repeat PP2C PF00481.21 KFM58970.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C CTP_synth_N PF06418.14 KFM58971.1 - 1.1e-128 428.1 0.1 2.2e-128 427.1 0.2 1.5 2 0 0 2 2 2 1 CTP synthase N-terminus GATase PF00117.28 KFM58971.1 - 3.4e-54 183.5 0.0 6.7e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFM58971.1 - 8.7e-07 28.9 0.1 3.2e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 KFM58971.1 - 0.015 15.3 0.1 0.028 14.5 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Arrestin_N PF00339.29 KFM58972.1 - 4.5e-29 101.4 0.3 2.7e-27 95.6 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFM58972.1 - 7.8e-22 78.2 0.0 1.7e-21 77.0 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Top6b_C PF18000.1 KFM58972.1 - 0.16 12.2 0.1 0.45 10.7 0.1 1.7 1 0 0 1 1 1 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain Peptidase_C65 PF10275.9 KFM58973.1 - 3.9e-22 78.9 0.1 5e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain HTH_Tnp_Tc3_2 PF01498.18 KFM58975.1 - 2.2e-16 59.9 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58975.1 - 3e-14 53.0 0.0 4.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PDZ PF00595.24 KFM58977.1 - 8.4e-38 128.6 5.0 1.9e-13 50.6 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFM58977.1 - 8.7e-15 54.3 1.0 0.0001 22.1 0.1 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFM58977.1 - 8.4e-12 45.2 1.1 0.00063 20.0 0.0 3.9 4 0 0 4 4 4 3 PDZ domain FGAR-AT_N PF18076.1 KFM58977.1 - 0.09 12.8 1.7 0.44 10.5 0.6 2.5 1 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase N-terminal adh_short PF00106.25 KFM58978.1 - 1.2e-07 31.4 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM58978.1 - 3.1e-07 30.2 0.0 3.1e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM58979.1 - 0.0011 18.5 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM58979.1 - 0.039 13.9 0.0 0.04 13.8 0.0 1.0 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KFM58979.1 - 0.14 11.2 0.0 0.15 11.2 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HTH_Tnp_Tc3_2 PF01498.18 KFM58980.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58980.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58980.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58980.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58980.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM58981.1 - 4.6e-17 62.0 1.4 6.5e-16 58.4 2.2 2.4 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58981.1 - 1.4e-13 50.9 0.0 2.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58981.1 - 3e-07 30.1 1.6 7.8e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58981.1 - 0.0031 17.3 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58981.1 - 3.1 8.5 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM58982.1 - 2.1e-16 59.9 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58982.1 - 7.7e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58983.1 - 2.4e-16 59.7 2.2 6.4e-16 58.4 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58983.1 - 1.1e-12 48.0 0.0 1.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58983.1 - 3.2e-07 30.0 1.6 7.8e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58983.1 - 0.003 17.3 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58983.1 - 2.7 8.7 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM58984.1 - 5.9e-16 58.5 0.1 5.3e-15 55.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM58984.1 - 6.8e-16 58.3 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM58984.1 - 0.00068 20.2 1.5 0.00068 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM58984.1 - 0.0022 17.7 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM58984.1 - 0.015 15.5 0.1 0.062 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM58984.1 - 0.032 14.2 2.6 0.033 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM58985.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM58985.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM58985.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM58985.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM58985.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM58987.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease MCM_bind PF09739.9 KFM58988.1 - 0.27 9.6 19.6 0.35 9.3 19.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor HTH_Tnp_Tc3_2 PF01498.18 KFM58992.1 - 2.7e-16 59.6 2.2 5.1e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM58992.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4757 PF15949.5 KFM58993.1 - 6.6e-17 62.5 9.0 6.6e-17 62.5 9.0 6.8 6 2 0 6 6 6 1 Domain of unknown function (DUF4757) LIM PF00412.22 KFM58993.1 - 1.5e-07 31.5 13.0 5e-07 29.8 13.0 2.0 1 0 0 1 1 1 1 LIM domain PDZ PF00595.24 KFM58993.1 - 3.7e-06 27.2 0.0 1.2e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM58993.1 - 1.4e-05 24.8 0.0 2.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM58993.1 - 0.0019 18.5 0.1 0.023 15.0 0.0 2.9 1 1 1 2 2 2 1 PDZ domain Noggin PF05806.12 KFM58994.1 - 0.59 10.0 5.0 0.74 9.7 5.0 1.0 1 0 0 1 1 1 0 Noggin CDC45 PF02724.14 KFM58994.1 - 3.9 5.7 13.7 4.1 5.6 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Med10 PF09748.9 KFM58995.1 - 3.2e-36 123.9 1.4 3.7e-36 123.7 1.4 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3793 PF12672.7 KFM58995.1 - 0.0034 17.5 0.1 0.0043 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3793) DUF316 PF03761.15 KFM58995.1 - 0.065 12.8 0.1 0.08 12.5 0.1 1.1 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Tmemb_18A PF09771.9 KFM58996.1 - 2.8e-57 192.2 0.6 3.2e-57 192.0 0.6 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 Intg_mem_TP0381 PF09529.10 KFM58996.1 - 0.021 14.4 1.4 0.024 14.2 1.4 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) Imm17 PF15562.6 KFM58996.1 - 0.13 12.1 3.3 0.46 10.4 3.3 1.9 1 1 0 1 1 1 0 Immunity protein 17 TPR_1 PF00515.28 KFM58997.1 - 2.5e-15 55.5 2.8 4.4e-06 26.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM58997.1 - 1.7e-14 52.6 1.4 3.5e-06 26.7 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM58997.1 - 3.5e-12 46.8 0.5 0.00018 22.1 0.7 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM58997.1 - 1.8e-11 43.3 1.9 6.8e-05 22.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM58997.1 - 3e-09 36.4 2.5 1.1e-05 25.0 0.7 3.1 1 1 2 3 3 3 2 TPR repeat TPR_10 PF13374.6 KFM58997.1 - 3.9e-09 36.1 0.4 0.043 13.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM58997.1 - 6.6e-09 35.9 0.6 0.0014 18.8 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM58997.1 - 2.1e-06 27.8 0.0 3.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM58997.1 - 5.3e-06 26.1 0.6 0.2 11.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM58997.1 - 3.9e-05 24.0 0.3 0.015 15.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM58997.1 - 6.8e-05 23.4 0.1 3.8 8.6 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM58997.1 - 0.00024 21.3 3.9 0.0069 16.7 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 KFM58997.1 - 0.00065 18.7 0.2 0.00077 18.5 0.2 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 KFM58997.1 - 0.00075 19.7 1.3 0.0034 17.6 1.2 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 SusD-like_3 PF14322.6 KFM58997.1 - 0.004 17.5 0.3 0.0089 16.4 0.2 1.5 1 1 1 2 2 2 1 Starch-binding associating with outer membrane TPR_19 PF14559.6 KFM58997.1 - 0.0045 17.5 0.4 2.9 8.5 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat MutH PF02976.15 KFM58997.1 - 0.026 14.5 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 DNA mismatch repair enzyme MutH Fis1_TPR_C PF14853.6 KFM58997.1 - 0.028 14.5 1.4 0.6 10.2 0.0 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 KFM58997.1 - 0.057 13.5 0.1 0.086 12.9 0.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 ThiF PF00899.21 KFM58998.1 - 8.3e-42 143.2 0.0 8.7e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFM58999.1 - 9.4e-24 83.4 0.2 1.1e-23 83.1 0.2 1.1 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 KFM58999.1 - 0.00014 22.4 0.0 0.00023 21.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain FeoA PF04023.14 KFM58999.1 - 0.0096 16.2 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 FeoA domain UBX PF00789.20 KFM58999.1 - 0.14 12.4 0.1 0.34 11.1 0.1 1.6 1 1 0 1 1 1 0 UBX domain RNase_H PF00075.24 KFM59000.1 - 3e-08 33.9 0.0 3.5e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM59000.1 - 0.00013 21.7 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like zf-HIT PF04438.16 KFM59001.1 - 1.9e-06 27.6 3.1 2.6e-06 27.2 3.1 1.2 1 0 0 1 1 1 1 HIT zinc finger PAPA-1 PF04795.12 KFM59001.1 - 0.00048 20.9 15.2 0.00048 20.9 15.2 2.2 2 1 0 2 2 2 1 PAPA-1-like conserved region Stathmin PF00836.19 KFM59001.1 - 0.2 11.6 15.3 0.91 9.5 15.3 1.9 1 1 0 1 1 1 0 Stathmin family ParB PF08775.10 KFM59001.1 - 0.67 10.5 9.4 0.96 9.9 9.4 1.3 1 0 0 1 1 1 0 ParB family FKBP_N PF01346.18 KFM59001.1 - 3.1 8.8 9.3 1.4 9.9 6.7 1.6 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase HTH_28 PF13518.6 KFM59003.1 - 1.5e-06 28.2 0.2 2.5e-06 27.5 0.1 1.5 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59003.1 - 0.0028 17.4 0.3 0.0035 17.1 0.3 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KFM59003.1 - 0.015 14.7 0.2 0.027 13.9 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 KFM59003.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 KFM59003.1 - 0.082 12.9 0.2 0.75 9.9 0.1 1.9 1 1 1 2 2 2 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 KFM59003.1 - 0.17 12.2 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 Transposase tRNA_anti-codon PF01336.25 KFM59005.1 - 2.2e-05 24.3 0.0 0.00074 19.5 0.0 2.1 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 KFM59005.1 - 0.19 10.7 0.0 0.42 9.5 0.0 1.5 2 0 0 2 2 2 0 Telomere regulation protein Stn1 YL1 PF05764.13 KFM59006.1 - 0.16 12.1 16.3 0.25 11.4 16.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein LYRIC PF15686.5 KFM59006.1 - 1.2 8.6 20.3 1.5 8.3 20.3 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF1387 PF07139.11 KFM59006.1 - 3.2 7.4 16.3 6.1 6.5 16.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1387) SPT6_acidic PF14632.6 KFM59006.1 - 4 8.1 27.6 3.4 8.3 6.7 2.1 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Peptidase_M24 PF00557.24 KFM59007.1 - 2.2e-21 76.5 0.0 2.6e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Na_K-ATPase PF00287.18 KFM59008.1 - 2.5e-24 85.9 0.0 3.3e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Tubulin_2 PF13809.6 KFM59008.1 - 0.21 10.7 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Tubulin like Ank_2 PF12796.7 KFM59010.1 - 5.7e-40 135.8 0.4 3.3e-14 53.2 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFM59010.1 - 2e-35 119.7 6.0 8.2e-06 26.0 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFM59010.1 - 1.3e-34 117.8 10.3 7e-09 35.8 0.1 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM59010.1 - 5.4e-34 112.4 3.5 0.00025 21.3 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KFM59010.1 - 2.4e-33 114.1 3.2 4.7e-10 39.8 0.0 5.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) SET PF00856.28 KFM59010.1 - 3.5e-22 79.6 0.1 9.1e-22 78.2 0.1 1.8 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 KFM59010.1 - 1e-17 64.8 12.6 2.2e-17 63.7 8.6 2.4 2 0 0 2 2 2 1 Pre-SET motif BTB_2 PF02214.22 KFM59011.1 - 5e-28 97.3 0.1 9.3e-28 96.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Shal-type PF11601.8 KFM59011.1 - 8.3e-15 54.0 13.4 1.3e-14 53.4 13.4 1.3 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal Ion_trans PF00520.31 KFM59011.1 - 4.3e-13 49.0 1.8 5.9e-13 48.6 1.8 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_3 PF16017.5 KFM59011.1 - 0.0011 19.0 0.0 0.0034 17.5 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Frizzled PF01534.17 KFM59012.1 - 5.7e-86 288.5 18.9 9.7e-86 287.7 18.9 1.3 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFM59012.1 - 4e-11 43.5 1.6 1.3e-10 41.9 1.6 1.9 1 0 0 1 1 1 1 Fz domain Dicty_CAR PF05462.11 KFM59012.1 - 0.00071 18.8 11.0 0.00071 18.8 11.0 1.8 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor PRRSV_2b PF07069.11 KFM59012.1 - 0.057 13.9 1.2 0.057 13.9 1.2 2.9 3 0 0 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b Lig_chan-Glu_bd PF10613.9 KFM59013.1 - 0.0082 16.3 0.0 0.01 16.0 0.0 1.1 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site 7tm_1 PF00001.21 KFM59015.1 - 2.8e-10 40.0 6.9 4.2e-10 39.4 6.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) rve PF00665.26 KFM59016.1 - 4e-07 30.3 0.0 4.1e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain SWIB PF02201.18 KFM59018.1 - 0.029 14.2 0.2 0.16 11.9 0.2 2.4 1 0 0 1 1 1 0 SWIB/MDM2 domain zf-RING_2 PF13639.6 KFM59019.1 - 2.6e-10 40.4 5.8 8e-10 38.9 5.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFM59019.1 - 3.6e-08 33.2 3.2 1e-07 31.7 3.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM59019.1 - 1.6e-07 31.1 3.6 4.9e-07 29.5 3.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM59019.1 - 3.4e-07 30.2 4.7 1.1e-06 28.6 4.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFM59019.1 - 1.3e-06 28.1 2.3 3.2e-06 26.9 2.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM59019.1 - 3.3e-06 27.3 4.7 1.3e-05 25.3 4.7 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM59019.1 - 4.5e-06 26.5 3.8 4.5e-06 26.5 3.8 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM59019.1 - 6.5e-05 23.0 1.9 0.00023 21.3 1.9 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFM59019.1 - 0.00038 20.3 2.0 0.0017 18.2 2.0 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFM59019.1 - 0.00091 18.9 1.3 0.0027 17.4 1.3 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 KFM59019.1 - 0.001 18.8 0.7 0.0024 17.7 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 KFM59019.1 - 0.0027 17.8 0.5 0.0066 16.5 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 KFM59019.1 - 0.0038 17.3 1.0 0.009 16.1 1.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_MLP1_2 PF07926.12 KFM59019.1 - 0.0038 17.3 10.8 0.0097 16.0 10.8 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein zf-RING_4 PF14570.6 KFM59019.1 - 0.0046 16.7 2.3 0.012 15.4 2.3 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Choline_kinase PF01633.20 KFM59019.1 - 0.0052 16.4 1.8 0.0092 15.6 1.8 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase WD40 PF00400.32 KFM59019.1 - 0.046 14.6 5.3 0.21 12.5 0.1 3.8 4 0 0 4 4 3 0 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KFM59019.1 - 0.051 13.2 2.8 0.13 11.9 2.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Phosducin PF02114.16 KFM59019.1 - 0.15 11.0 3.8 0.27 10.1 3.8 1.4 1 0 0 1 1 1 0 Phosducin FANCL_C PF11793.8 KFM59019.1 - 0.57 10.4 3.7 2.1 8.6 3.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KFM59019.1 - 0.65 10.2 6.5 3.3 7.9 6.5 2.4 1 0 0 1 1 1 0 RING-variant domain DUF3523 PF12037.8 KFM59019.1 - 1.8 7.9 18.2 0.034 13.5 10.4 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3523) Glucan_synthase PF02364.15 KFM59019.1 - 5.3 5.1 5.9 7.6 4.6 5.9 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component HTH_Tnp_Tc3_2 PF01498.18 KFM59020.1 - 2.7e-14 53.2 1.0 5e-14 52.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59020.1 - 6.2e-14 52.0 0.0 8e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM59021.1 - 2.2e-16 59.9 0.1 2.6e-15 56.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59021.1 - 1.3e-10 41.4 1.0 2.4e-10 40.5 1.0 1.5 1 0 0 1 1 1 1 Transposase 7tm_2 PF00002.24 KFM59022.1 - 7.3e-44 149.9 11.8 1.2e-43 149.1 11.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFM59022.1 - 2e-26 92.7 0.5 3.7e-26 91.9 0.5 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.18 KFM59022.1 - 7.3e-17 61.6 0.3 2.1e-16 60.1 0.1 2.0 2 0 0 2 2 2 1 Galactose binding lectin domain GPS PF01825.21 KFM59022.1 - 6.3e-14 52.2 4.8 2.1e-13 50.5 4.8 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Dicty_CAR PF05462.11 KFM59022.1 - 4.6e-08 32.5 5.1 7.3e-08 31.9 5.1 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor HRM PF02793.22 KFM59022.1 - 0.0027 18.0 4.8 0.0054 17.0 3.2 2.4 2 0 0 2 2 2 1 Hormone receptor domain Ni_hydr_CYTB PF01292.20 KFM59022.1 - 0.1 12.2 0.8 0.24 11.0 0.8 1.6 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Cytochrom_B561 PF03188.16 KFM59022.1 - 1.3 9.1 7.4 0.7 10.0 1.4 2.4 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DDE_3 PF13358.6 KFM59023.1 - 2.6e-16 59.7 0.1 2.7e-15 56.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59023.1 - 1.3e-10 41.3 1.0 2.3e-10 40.5 1.0 1.4 1 0 0 1 1 1 1 Transposase Homeobox_KN PF05920.11 KFM59026.1 - 7.4e-16 57.8 1.3 2.4e-15 56.1 0.4 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KFM59026.1 - 4.8e-07 29.5 0.8 1.1e-06 28.3 0.8 1.6 1 0 0 1 1 1 1 Homeodomain R-HINP1I PF11463.8 KFM59026.1 - 0.051 13.0 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease PH_16 PF17838.1 KFM59028.1 - 9.9e-35 119.1 0.2 4.4e-34 117.0 0.0 2.2 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.20 KFM59028.1 - 2e-30 106.4 8.9 3.8e-30 105.5 8.9 1.5 1 0 0 1 1 1 1 RhoGEF domain C1_1 PF00130.22 KFM59028.1 - 0.00013 21.8 9.3 0.00033 20.5 9.3 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFM59028.1 - 0.031 14.8 0.0 0.031 14.8 0.0 3.1 4 0 0 4 4 4 0 PH domain Bacillus_HBL PF05791.11 KFM59030.1 - 0.0011 18.9 0.9 0.0026 17.6 0.9 1.6 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.12 KFM59030.1 - 0.047 13.8 14.1 0.11 12.5 14.1 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 KFM59030.1 - 0.49 9.6 3.6 0.89 8.7 3.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 KFM59030.1 - 0.56 8.0 3.8 0.77 7.6 3.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ion_trans PF00520.31 KFM59031.1 - 1.2e-47 162.3 36.2 2e-27 96.0 17.7 2.1 2 0 0 2 2 2 2 Ion transport protein EF-hand_1 PF00036.32 KFM59031.1 - 0.0065 15.9 0.1 0.019 14.5 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFM59031.1 - 0.016 15.1 0.1 0.065 13.2 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 KFM59031.1 - 0.061 13.2 0.2 0.18 11.6 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 KFM59031.1 - 0.08 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair PKD_channel PF08016.12 KFM59031.1 - 0.4 9.3 29.5 0.32 9.6 11.2 3.5 3 1 1 4 4 4 0 Polycystin cation channel DUF4229 PF14012.6 KFM59032.1 - 0.014 15.5 0.9 0.03 14.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Halogen_Hydrol PF10112.9 KFM59032.1 - 0.019 15.0 0.6 0.037 14.1 0.6 1.4 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein YMF19 PF02326.15 KFM59032.1 - 3 8.7 6.0 1.8 9.4 3.3 2.0 1 1 0 2 2 2 0 Plant ATP synthase F0 DDE_3 PF13358.6 KFM59034.1 - 8.6e-16 58.0 0.1 9.8e-15 54.6 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59034.1 - 1.4e-10 41.3 1.0 2.6e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59035.1 - 2.1e-16 60.0 0.1 2.4e-15 56.6 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59035.1 - 1.2e-10 41.5 1.0 2.3e-10 40.5 1.0 1.5 1 0 0 1 1 1 1 Transposase Peptidase_M13 PF01431.21 KFM59037.1 - 2.2e-20 73.1 0.0 2.4e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 SDF PF00375.18 KFM59038.1 - 2.7e-53 181.4 10.4 3.3e-53 181.1 10.4 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF446 PF04287.12 KFM59038.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase C TPR_1 PF00515.28 KFM59041.1 - 8.4e-30 101.4 10.5 4.2e-10 39.0 2.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM59041.1 - 7.5e-23 78.8 8.0 1.8e-06 27.6 1.3 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM59041.1 - 2.4e-19 68.7 12.3 2.8e-06 26.9 2.0 4.1 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 KFM59041.1 - 4.4e-19 67.0 10.5 1.3e-06 28.1 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM59041.1 - 2.6e-14 52.1 1.1 0.0046 16.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM59041.1 - 8.7e-13 48.4 5.1 1.3e-07 31.7 0.6 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM59041.1 - 1.9e-12 46.6 9.9 6.5e-05 23.0 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM59041.1 - 3.9e-12 46.6 0.3 2.1e-08 34.7 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat SGTA_dimer PF16546.5 KFM59041.1 - 2.7e-11 43.1 1.9 6.2e-11 41.9 0.4 2.2 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_14 PF13428.6 KFM59041.1 - 9e-11 41.7 2.2 0.0052 17.5 0.0 4.4 3 1 2 5 5 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFM59041.1 - 5.5e-10 38.8 6.4 0.0053 16.6 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFM59041.1 - 1.6e-07 31.4 0.1 0.0016 18.5 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM59041.1 - 2.6e-07 31.0 3.6 1.2e-05 25.7 0.2 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFM59041.1 - 4.6e-05 22.8 2.4 0.0018 17.5 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TOM20_plant PF06552.12 KFM59041.1 - 0.00021 21.1 3.5 0.0039 17.0 0.4 3.5 1 1 2 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.6 KFM59041.1 - 0.00027 21.4 1.6 0.18 12.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFM59041.1 - 0.0013 18.2 0.7 0.95 9.0 0.0 3.6 3 0 0 3 3 3 1 SHNi-TPR BTAD PF03704.17 KFM59041.1 - 0.0031 17.9 1.5 0.26 11.7 0.1 2.9 1 1 2 3 3 3 2 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 KFM59041.1 - 0.011 15.8 4.8 0.93 9.6 0.4 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat XPC-binding PF09280.11 KFM59041.1 - 0.012 15.3 0.2 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 XPC-binding domain Gag_p24 PF00607.20 KFM59041.1 - 0.22 11.3 2.0 1.5 8.7 0.0 2.9 2 1 1 3 3 3 0 gag gene protein p24 (core nucleocapsid protein) ANAPC3 PF12895.7 KFM59041.1 - 0.27 11.5 6.3 0.63 10.3 4.4 2.6 2 1 2 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KFM59041.1 - 3.1 7.5 7.8 1.2 8.8 0.5 2.5 2 1 1 3 3 3 0 26S proteasome subunit RPN7 S1 PF00575.23 KFM59043.1 - 7.3e-13 48.7 8.0 0.0012 19.2 0.0 5.1 4 1 1 5 5 5 3 S1 RNA binding domain Tudor_FRX1 PF18336.1 KFM59043.1 - 0.28 11.1 1.3 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Fragile X mental retardation Tudor domain Orn_Arg_deC_N PF02784.16 KFM59044.1 - 1e-62 211.7 0.0 1.3e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain SPOB_ab PF14682.6 KFM59044.1 - 0.049 13.7 0.1 7 6.8 0.0 2.9 2 1 1 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal AP_endonuc_2 PF01261.24 KFM59044.1 - 0.05 13.0 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Orn_DAP_Arg_deC PF00278.22 KFM59044.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.4 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain HTH_Tnp_Tc3_2 PF01498.18 KFM59045.1 - 2.1e-16 59.9 3.0 5.5e-16 58.6 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM59045.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59045.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59045.1 - 0.0027 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59045.1 - 0.031 14.4 0.4 0.088 13.0 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM59045.1 - 2.1 9.0 14.8 0.11 13.1 1.8 3.1 2 1 1 3 3 3 0 Homeodomain-like domain 7tm_1 PF00001.21 KFM59046.1 - 3.8e-45 154.3 1.6 4.2e-45 154.1 1.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM59046.1 - 0.00014 21.6 3.4 0.00021 21.0 3.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFM59046.1 - 0.0088 15.5 1.4 0.013 14.9 1.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFM59046.1 - 0.04 13.6 0.2 0.09 12.5 0.0 1.6 2 0 0 2 2 2 0 Olfactory receptor PEN-2 PF10251.9 KFM59046.1 - 0.34 11.4 0.1 0.34 11.4 0.1 1.9 2 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase HTH_Tnp_Tc3_2 PF01498.18 KFM59048.1 - 5.2e-16 58.7 3.5 6e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59048.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59048.1 - 3e-07 30.1 1.6 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59048.1 - 0.0029 17.3 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59048.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain SAP18 PF06487.12 KFM59050.1 - 1.7e-14 54.1 0.0 2.1e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) zf-C2H2 PF00096.26 KFM59052.1 - 2.4e-19 68.6 33.6 2.6e-05 24.4 0.6 6.7 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM59052.1 - 9e-12 44.9 40.0 1.2e-07 31.8 0.1 7.2 8 0 0 8 8 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM59052.1 - 1.9e-11 43.7 31.3 0.0069 17.1 0.7 6.6 6 1 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 KFM59052.1 - 2.2e-07 31.0 22.4 0.076 13.4 0.1 5.8 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KFM59052.1 - 1.9e-05 24.9 17.1 0.98 9.5 0.1 4.6 1 1 2 4 4 4 3 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFM59052.1 - 0.001 19.0 0.4 0.001 19.0 0.4 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM59052.1 - 0.0014 18.9 22.6 0.031 14.6 0.1 5.4 5 1 0 5 5 5 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KFM59052.1 - 0.0091 16.6 15.9 0.44 11.2 0.5 4.9 3 2 2 5 5 5 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFM59052.1 - 0.012 15.8 13.4 0.046 14.0 2.6 3.4 1 1 2 3 3 3 0 C2H2-type zinc ribbon Allantoicase PF03561.15 KFM59052.1 - 0.13 12.3 0.2 21 5.1 0.0 2.8 2 1 0 2 2 2 0 Allantoicase repeat zf-C2H2_11 PF16622.5 KFM59052.1 - 0.18 11.6 3.9 15 5.4 0.1 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFM59052.1 - 0.19 12.1 15.9 4.2 7.8 0.7 4.0 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) HTH_Tnp_Tc3_2 PF01498.18 KFM59053.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59053.1 - 7.4e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease THAP PF05485.12 KFM59055.1 - 2.8e-07 31.4 0.1 2.8e-07 31.4 0.1 1.0 1 0 0 1 1 1 1 THAP domain Ion_trans_2 PF07885.16 KFM59056.1 - 1.4e-22 79.4 9.6 1.4e-22 79.4 9.6 1.6 2 0 0 2 2 2 1 Ion channel AP3D1 PF06375.11 KFM59056.1 - 0.0019 18.5 13.8 0.11 12.7 11.2 2.4 2 0 0 2 2 2 2 AP-3 complex subunit delta-1 Connexin PF00029.19 KFM59056.1 - 0.0035 17.1 0.3 0.0071 16.1 0.3 1.6 1 0 0 1 1 1 1 Connexin Ion_trans PF00520.31 KFM59056.1 - 0.011 15.0 11.8 0.017 14.4 11.8 1.4 1 1 0 1 1 1 0 Ion transport protein CSG2 PF16965.5 KFM59056.1 - 0.042 12.8 0.1 0.055 12.4 0.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4337 PF14235.6 KFM59056.1 - 0.11 12.6 0.3 0.2 11.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4603 PF15376.6 KFM59056.1 - 0.12 9.7 7.7 0.16 9.3 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) NARP1 PF12569.8 KFM59056.1 - 0.34 9.8 7.5 0.44 9.4 7.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF809 PF05663.11 KFM59056.1 - 1.1 9.4 9.1 17 5.5 10.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF809) NPR3 PF03666.13 KFM59056.1 - 1.6 7.5 8.4 2.7 6.7 8.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PPL5 PF18168.1 KFM59056.1 - 2.7 7.2 7.8 3.7 6.8 7.0 1.6 2 0 0 2 2 2 0 Prim-pol family 5 Zip PF02535.22 KFM59056.1 - 5.6 6.1 9.0 8 5.6 8.4 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter YqfQ PF14181.6 KFM59056.1 - 7.6 6.7 16.3 1 9.5 10.8 1.9 2 0 0 2 2 2 0 YqfQ-like protein RNA_polI_A34 PF08208.11 KFM59056.1 - 8 6.5 22.7 16 5.5 22.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 EB PF01683.18 KFM59057.1 - 6.6e-06 26.3 0.9 7.7e-06 26.1 0.9 1.2 1 0 0 1 1 1 1 EB module RdgC PF04381.12 KFM59058.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Putative exonuclease, RdgC SCA7 PF08313.12 KFM59060.1 - 6.7e-19 67.5 1.8 1.7e-18 66.2 1.8 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain Mucin-like PF16058.5 KFM59060.1 - 4.2e-07 30.0 22.1 4.2e-07 30.0 22.1 3.9 3 1 1 4 4 4 2 Mucin-like OrsD PF12013.8 KFM59060.1 - 0.069 13.6 0.1 0.069 13.6 0.1 2.3 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D HTH_Tnp_Tc3_2 PF01498.18 KFM59061.1 - 0.015 15.6 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Transposase Laps PF10169.9 KFM59062.1 - 2.1e-10 41.3 0.8 2.1e-10 41.2 0.8 1.0 1 0 0 1 1 1 1 Learning-associated protein Laps PF10169.9 KFM59063.1 - 4.3e-16 59.6 5.9 4.4e-16 59.6 5.9 1.0 1 0 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 KFM59063.1 - 3.3e-05 24.0 6.6 5.5e-05 23.3 6.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2423) AHD PF17793.1 KFM59063.1 - 0.017 14.9 0.1 0.022 14.5 0.1 1.2 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Nnf1 PF03980.14 KFM59063.1 - 0.032 14.6 1.3 0.035 14.5 0.9 1.3 1 1 0 1 1 1 0 Nnf1 Nup96 PF12110.8 KFM59064.1 - 4e-87 292.0 3.9 5.7e-87 291.5 3.9 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KFM59065.1 - 3.8e-28 98.5 0.0 9.8e-28 97.1 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KFM59065.1 - 2.4e-06 28.3 235.4 0.022 15.6 36.1 8.1 3 2 5 8 8 8 5 Nucleoporin FG repeat region Peptidase_C98 PF15499.6 KFM59068.1 - 5.5e-49 167.1 2.5 5.5e-49 167.1 2.5 1.9 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase UCH PF00443.29 KFM59068.1 - 0.75 9.2 14.3 0.11 11.9 0.9 3.6 3 2 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Nuc_deoxyri_tr2 PF15891.5 KFM59070.1 - 1.2e-18 67.3 0.0 5.2e-14 52.5 0.0 2.4 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like EF-hand_6 PF13405.6 KFM59070.1 - 0.015 15.1 0.8 0.17 11.9 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 KFM59070.1 - 0.039 14.4 0.2 0.13 12.8 0.2 1.9 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KFM59070.1 - 0.065 12.8 3.6 1.1 9.0 0.4 3.0 3 0 0 3 3 3 0 EF hand SH3_19 PF18597.1 KFM59073.1 - 0.015 15.1 7.2 41 4.1 0.0 5.9 1 1 5 6 6 6 0 Myosin X N-terminal SH3 domain Rhamno_transf PF11316.8 KFM59073.1 - 1.1 8.6 3.4 2.6 7.3 1.1 2.0 1 1 1 2 2 2 0 Putative rhamnosyl transferase RVT_1 PF00078.27 KFM59076.1 - 4.3e-18 65.7 0.0 6.3e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4208 PF13907.6 KFM59076.1 - 0.06 13.8 1.7 0.17 12.3 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) F_actin_bind PF08919.10 KFM59076.1 - 0.09 12.9 0.2 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 F-actin binding DUF1664 PF07889.12 KFM59076.1 - 0.15 12.1 2.4 0.55 10.3 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KFM59076.1 - 0.54 10.3 4.1 0.56 10.3 2.1 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KFM59076.1 - 0.93 9.9 7.1 3.4 8.1 5.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Phasin PF05597.11 KFM59076.1 - 1.2 9.1 5.6 0.26 11.3 2.2 1.5 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RbcS PF12338.8 KFM59077.1 - 0.18 12.0 3.4 0.9 9.8 0.1 3.6 3 0 0 3 3 3 0 Ribulose-1,5-bisphosphate carboxylase small subunit MNE1 PF13762.6 KFM59079.1 - 0.017 15.1 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component DUF3300 PF11737.8 KFM59080.1 - 0.35 10.4 1.6 0.35 10.4 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) DUF5529 PF17669.1 KFM59081.1 - 0.0047 17.0 1.4 0.006 16.6 1.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5529) HTH_48 PF17906.1 KFM59082.1 - 6.6e-13 48.6 0.3 1.3e-12 47.7 0.3 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_3 PF01381.22 KFM59082.1 - 0.0037 17.3 0.0 0.0097 15.9 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 KFM59082.1 - 0.0088 16.2 0.2 0.063 13.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59082.1 - 0.018 14.8 1.1 0.28 11.0 0.1 2.5 1 1 1 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 KFM59082.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MARVEL PF01284.23 KFM59083.1 - 0.00012 22.2 5.4 0.00023 21.2 5.4 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 KFM59083.1 - 0.3 10.8 4.4 0.34 10.7 3.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF588) MARVEL PF01284.23 KFM59084.1 - 0.0058 16.7 8.5 0.0081 16.2 8.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2663 PF10864.8 KFM59084.1 - 0.096 13.1 0.3 0.18 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) LAGLIDADG_2 PF03161.13 KFM59085.1 - 0.15 12.1 0.1 0.36 10.8 0.0 1.6 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family DSPc PF00782.20 KFM59086.1 - 3e-34 117.7 0.0 4.2e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM59086.1 - 0.00017 21.2 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 7tm_2 PF00002.24 KFM59088.1 - 2.3e-15 56.6 15.4 3.6e-15 55.9 15.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFM59088.1 - 1.9e-09 37.9 2.9 2.1e-09 37.8 0.4 2.5 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif NOA36 PF06524.12 KFM59088.1 - 6.1 6.1 11.4 15 4.8 11.4 1.6 1 0 0 1 1 1 0 NOA36 protein Transglut_C PF00927.22 KFM59089.1 - 1.3e-28 99.2 0.0 1.7e-13 50.6 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 KFM59089.1 - 7.7e-27 94.0 0.0 2.5e-26 92.4 0.0 1.9 2 0 0 2 2 2 1 Transglutaminase family Transglut_core PF01841.19 KFM59089.1 - 8.3e-17 61.7 0.1 1.7e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF4116 PF13475.6 KFM59089.1 - 0.075 12.8 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1616 PF07760.11 KFM59089.1 - 0.083 12.3 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Transglut_N PF00868.20 KFM59090.1 - 1.6e-28 99.4 0.0 8.5e-27 93.9 0.0 3.0 3 0 0 3 3 3 1 Transglutaminase family Transglut_C PF00927.22 KFM59090.1 - 5.4e-28 97.2 0.0 1.4e-13 50.9 0.1 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFM59090.1 - 4.7e-15 56.0 0.4 1.7e-14 54.2 0.2 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily HCBP_related PF06594.11 KFM59090.1 - 0.0081 16.1 1.1 0.021 14.8 1.1 1.7 1 0 0 1 1 1 1 Haemolysin-type calcium binding protein related domain SecA_DEAD PF07517.14 KFM59090.1 - 0.05 12.9 0.2 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain MARVEL PF01284.23 KFM59091.1 - 1.2e-17 64.3 20.0 1.5e-17 63.9 20.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3687 PF12459.8 KFM59091.1 - 0.024 14.1 2.0 0.059 12.9 2.0 1.6 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein TMEM192 PF14802.6 KFM59091.1 - 1.4 8.0 3.8 1.8 7.6 3.8 1.1 1 0 0 1 1 1 0 TMEM192 family Pkinase PF00069.25 KFM59094.1 - 4.2e-59 200.0 0.0 7.7e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM59094.1 - 4.2e-32 111.4 0.0 1e-31 110.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.22 KFM59094.1 - 4e-25 87.4 21.7 8.9e-13 47.9 4.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFM59094.1 - 2.3e-05 24.9 1.8 3.2e-05 24.4 0.4 2.1 2 0 0 2 2 1 1 PH domain C1_2 PF03107.16 KFM59094.1 - 0.00016 22.0 1.7 0.00016 22.0 1.7 2.7 2 0 0 2 2 2 1 C1 domain Kdo PF06293.14 KFM59094.1 - 0.00023 20.6 0.1 0.00046 19.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM59094.1 - 0.0064 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFM59094.1 - 0.01 15.4 0.4 0.019 14.6 0.4 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KFM59094.1 - 0.025 14.5 0.1 0.083 12.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family PHD_2 PF13831.6 KFM59094.1 - 0.29 10.7 10.6 0.89 9.2 2.1 2.8 2 0 0 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 KFM59094.1 - 3.2 7.7 17.0 0.043 13.8 3.1 2.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 KFM59094.1 - 4.3 7.3 19.0 0.24 11.3 3.5 2.7 2 0 0 2 2 2 0 PHD-finger Cadherin PF00028.17 KFM59095.1 - 1.3e-51 173.0 5.1 1e-16 61.1 0.1 4.6 4 1 0 4 4 4 4 Cadherin domain Comm PF15957.5 KFM59095.1 - 0.0044 17.4 0.1 0.0081 16.5 0.1 1.4 1 0 0 1 1 1 1 Commissureless Cadherin_3 PF16184.5 KFM59095.1 - 0.0093 16.0 5.4 1.6 8.8 0.0 4.2 4 1 0 4 4 4 2 Cadherin-like Cadherin_2 PF08266.12 KFM59095.1 - 0.11 12.3 0.1 24 4.8 0.0 3.4 3 0 0 3 3 3 0 Cadherin-like RET_CLD1 PF17756.1 KFM59095.1 - 0.13 12.6 0.0 15 5.9 0.0 3.4 4 0 0 4 4 4 0 RET Cadherin like domain 1 SAA PF00277.18 KFM59096.1 - 8.9e-47 157.8 6.0 1e-46 157.6 6.0 1.0 1 0 0 1 1 1 1 Serum amyloid A protein SAA PF00277.18 KFM59097.1 - 3.4e-38 130.2 4.3 4.2e-38 129.9 4.3 1.1 1 0 0 1 1 1 1 Serum amyloid A protein HTH_Tnp_Tc3_2 PF01498.18 KFM59098.1 - 4e-16 59.0 4.1 5.6e-16 58.5 2.2 2.2 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM59098.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59098.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59098.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59098.1 - 0.025 14.7 0.4 0.089 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM59098.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain RVT_1 PF00078.27 KFM59099.1 - 1.4e-54 185.0 0.6 2.1e-54 184.4 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.18 KFM59100.1 - 2.6e-16 59.6 2.8 4.8e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59100.1 - 6.5e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59100.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59100.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59100.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain tRNA-synt_1g PF09334.11 KFM59101.1 - 5.5e-150 499.5 0.2 7.3e-150 499.1 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 KFM59101.1 - 5.7e-15 55.2 3.8 1.5e-14 53.8 3.8 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 KFM59101.1 - 2.7e-10 39.1 0.3 8.2e-07 27.7 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) GST_N_5 PF18485.1 KFM59101.1 - 0.003 17.9 0.0 0.01 16.2 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KFM59101.1 - 0.0081 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KFM59101.1 - 0.079 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain zinc-ribbons_6 PF07191.12 KFM59101.1 - 5.6 7.0 8.8 16 5.5 8.8 1.8 1 0 0 1 1 1 0 zinc-ribbons Pkinase PF00069.25 KFM59102.1 - 1.1e-07 31.5 0.0 1.4e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DDE_1 PF03184.19 KFM59103.1 - 2.8e-08 33.6 0.0 4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3578 PF12102.8 KFM59103.1 - 0.0096 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3578) HTH_Tnp_Tc3_2 PF01498.18 KFM59104.1 - 2.3e-16 59.8 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59104.1 - 9.8e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM59105.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4371) CSTF2_hinge PF14327.6 KFM59105.1 - 0.11 13.0 0.1 0.26 11.8 0.1 1.7 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Pribosyltran PF00156.27 KFM59107.1 - 0.0041 16.7 0.0 0.0046 16.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CDK5_activator PF03261.15 KFM59109.1 - 2e-82 277.6 0.2 2.4e-82 277.4 0.2 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein HSP20 PF00011.21 KFM59110.1 - 2.3e-28 98.3 1.0 3e-28 98.0 1.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFM59110.1 - 0.003 17.7 0.1 0.0046 17.1 0.1 1.3 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal ArsA_HSP20 PF17886.1 KFM59110.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Cupredoxin_1 PF13473.6 KFM59110.1 - 0.023 14.8 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain 7tm_1 PF00001.21 KFM59111.1 - 9e-38 130.1 7.7 1.1e-37 129.8 7.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFM59111.1 - 1.1e-07 31.9 3.8 1.1e-07 31.9 3.8 1.6 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 KFM59111.1 - 0.00017 21.0 3.8 0.00017 21.0 3.8 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFM59111.1 - 0.00048 19.9 11.9 0.00071 19.3 11.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFM59111.1 - 0.0022 17.4 10.8 0.0042 16.5 10.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PDEase_I PF00233.19 KFM59113.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Kelch_1 PF01344.25 KFM59114.1 - 5.1e-42 141.2 13.1 3.5e-10 39.3 0.0 6.4 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFM59114.1 - 7e-42 140.4 5.8 1.1e-07 31.9 0.0 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFM59114.1 - 6.6e-40 133.6 11.2 4.3e-07 29.6 0.1 6.5 6 1 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KFM59114.1 - 1.5e-39 133.3 7.7 7.8e-07 29.0 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFM59114.1 - 9.6e-39 131.2 1.6 7.5e-06 25.9 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFM59114.1 - 2.9e-33 113.5 3.8 1.4e-09 38.0 0.0 7.4 7 1 0 7 7 7 5 Galactose oxidase, central domain RAG2 PF03089.14 KFM59114.1 - 0.0089 15.0 0.5 1.6 7.7 0.1 3.2 1 1 1 2 2 2 1 Recombination activating protein 2 Toxin_9 PF02819.15 KFM59114.1 - 0.11 12.8 0.7 0.22 11.8 0.7 1.4 1 0 0 1 1 1 0 Spider toxin HTH_Tnp_Tc3_2 PF01498.18 KFM59115.1 - 1.9e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59115.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Pribosyl_synth PF14572.6 KFM59116.1 - 0.0097 16.0 0.2 0.012 15.7 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Na_Ca_ex PF01699.24 KFM59118.1 - 1.1e-52 178.0 45.8 1.6e-29 102.8 23.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein zf-NF-X1 PF01422.17 KFM59119.1 - 6.1e-09 35.8 55.6 1.7e-06 27.9 14.6 10.6 11 0 0 11 11 11 6 NF-X1 type zinc finger ATG13 PF10033.9 KFM59120.1 - 5.2e-14 52.5 1.8 8e-09 35.5 0.1 3.1 1 1 1 2 2 2 2 Autophagy-related protein 13 zf-CCHC PF00098.23 KFM59121.1 - 1.2e-51 170.6 63.7 1.9e-08 34.0 2.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KFM59121.1 - 4.5e-12 45.5 46.9 0.015 15.0 0.8 7.1 6 1 1 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM59121.1 - 4.3e-11 42.4 43.4 0.028 14.1 0.8 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 KFM59121.1 - 4.9e-11 42.4 40.6 0.034 14.1 0.9 7.1 2 1 5 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.6 KFM59121.1 - 4.7 7.1 57.6 0.6 10.0 1.1 7.1 7 0 0 7 7 7 0 Zinc knuckle DUF4728 PF15860.5 KFM59122.1 - 3.9e-08 33.9 11.2 3.9e-08 33.9 11.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4728) Tetraspanin PF00335.20 KFM59122.1 - 0.046 13.4 12.9 0.036 13.8 11.8 1.4 1 1 0 1 1 1 0 Tetraspanin family YibE_F PF07907.11 KFM59122.1 - 0.13 11.7 7.2 0.033 13.7 3.7 1.7 2 0 0 2 2 2 0 YibE/F-like protein Cys_rich_FGFR PF00839.17 KFM59123.1 - 0.015 15.4 0.6 0.063 13.5 0.1 1.9 2 0 0 2 2 2 0 Cysteine rich repeat ACP_syn_III_C PF08541.10 KFM59123.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ASD2 PF08687.11 KFM59125.1 - 2.4e-39 135.7 9.7 2.4e-39 135.7 9.7 2.0 2 0 0 2 2 2 1 Apx/Shroom domain ASD2 PDZ PF00595.24 KFM59125.1 - 2.6e-09 37.3 0.0 5.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM59125.1 - 1.1e-08 34.7 0.1 2e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM59125.1 - 6.7e-06 26.3 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF16 PF01519.16 KFM59125.1 - 0.51 10.9 4.0 4.1 7.9 4.0 2.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 M PF02370.16 KFM59125.1 - 0.82 10.4 5.5 25 5.9 2.4 3.2 2 0 0 2 2 2 0 M protein repeat Matrilin_ccoil PF10393.9 KFM59125.1 - 3 7.8 6.3 3.7 7.5 0.2 3.2 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin MIP PF00230.20 KFM59126.1 - 0.074 12.8 8.7 0.021 14.5 4.3 2.0 2 1 0 2 2 2 0 Major intrinsic protein wnt PF00110.19 KFM59127.1 - 8.1e-116 386.9 26.5 9e-116 386.8 26.5 1.0 1 0 0 1 1 1 1 wnt family HEAT PF02985.22 KFM59129.1 - 0.0032 17.6 0.0 0.072 13.4 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.6 KFM59129.1 - 0.051 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 HEAT repeats Putative_PNPOx PF01243.20 KFM59131.1 - 5.3e-24 84.2 0.0 8.5e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KFM59131.1 - 5e-17 61.7 1.0 8.6e-17 61.0 1.0 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KFM59131.1 - 8.2e-07 29.6 0.0 1.6e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KFM59131.1 - 0.039 13.5 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like EF-hand_7 PF13499.6 KFM59133.1 - 3.5e-10 40.2 10.4 4e-10 40.0 5.3 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM59133.1 - 8.3e-08 31.3 11.7 0.00016 21.0 0.5 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFM59133.1 - 2.6e-06 26.9 7.2 0.00024 20.8 0.4 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFM59133.1 - 2.3e-05 24.1 8.0 0.019 14.8 2.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM59133.1 - 0.41 10.2 4.7 0.25 10.9 0.4 2.5 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 KFM59133.1 - 0.42 11.0 3.5 0.29 11.5 0.2 2.0 2 0 0 2 2 2 0 EF-hand domain Zn_ribbon_17 PF17120.5 KFM59135.1 - 0.97 9.1 4.7 1.1 8.9 2.2 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type HTH_Tnp_Tc3_2 PF01498.18 KFM59137.1 - 8.2e-28 96.5 20.3 3.9e-15 55.8 6.5 3.1 3 0 0 3 3 3 2 Transposase DDE_3 PF13358.6 KFM59137.1 - 1.8e-13 50.5 0.0 1.7e-11 44.1 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59137.1 - 2.9e-07 31.0 21.1 8.4e-05 23.1 2.4 4.1 4 0 0 4 4 4 2 Homeodomain-like domain HTH_28 PF13518.6 KFM59137.1 - 0.00011 22.3 5.4 0.34 11.1 0.1 3.6 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.6 KFM59137.1 - 0.00018 21.2 6.5 0.27 11.1 0.0 4.2 4 0 0 4 4 4 2 Homeodomain-like domain HTH_7 PF02796.15 KFM59137.1 - 0.00095 19.2 0.8 0.79 9.9 0.0 2.9 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_3 PF01381.22 KFM59137.1 - 0.0071 16.4 3.7 0.07 13.2 0.0 3.5 4 0 0 4 4 4 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM59137.1 - 0.017 15.1 1.6 0.12 12.4 0.1 2.9 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KFM59137.1 - 0.023 14.6 3.0 0.16 11.9 0.0 2.9 3 0 0 3 3 2 0 MarR family PAX PF00292.18 KFM59137.1 - 0.024 14.6 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 'Paired box' domain Sds3 PF08598.11 KFM59137.1 - 0.026 14.5 2.4 0.051 13.6 2.4 1.4 1 0 0 1 1 1 0 Sds3-like HTH_29 PF13551.6 KFM59137.1 - 0.042 13.9 7.4 0.22 11.6 0.2 3.3 4 0 0 4 4 4 0 Winged helix-turn helix Thioesterase PF00975.20 KFM59137.1 - 0.087 12.9 0.2 0.32 11.1 0.1 1.9 2 0 0 2 2 2 0 Thioesterase domain HTH_24 PF13412.6 KFM59137.1 - 0.2 11.3 0.7 1.9 8.1 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding ThylakoidFormat PF11264.8 KFM59137.1 - 0.21 11.3 2.5 4.8 6.8 1.3 2.2 2 0 0 2 2 2 0 Thylakoid formation protein RVT_2 PF07727.14 KFM59138.1 - 3e-72 243.2 0.2 7.1e-72 242.0 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KFM59138.1 - 1.2e-23 83.3 0.1 3e-23 82.0 0.1 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 KFM59138.1 - 9.7e-14 51.6 0.0 4.9e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain DUF4219 PF13961.6 KFM59138.1 - 3e-06 26.8 0.3 7.5e-06 25.5 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.6 KFM59138.1 - 0.00015 21.6 0.6 0.00038 20.3 0.1 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 KFM59138.1 - 0.00088 19.0 0.0 0.0034 17.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 KFM59138.1 - 0.032 14.5 0.0 0.59 10.4 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein HTH_48 PF17906.1 KFM59139.1 - 3.5e-09 36.6 0.0 6.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM59139.1 - 9e-06 26.2 1.4 5e-05 23.8 0.3 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59139.1 - 0.017 14.9 1.2 1 9.2 0.1 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_17 PF12728.7 KFM59139.1 - 0.044 14.0 0.0 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 KFM59139.1 - 0.049 13.4 0.0 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 HTH DNA binding domain Sigma70_r4 PF04545.16 KFM59139.1 - 0.073 12.6 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 KFM59139.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding RNase_H PF00075.24 KFM59141.1 - 1.2e-06 28.8 0.2 3.2e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.6 KFM59141.1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like DDE_3 PF13358.6 KFM59142.1 - 5.2e-10 39.3 0.0 9.1e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-RING_2 PF13639.6 KFM59144.1 - 0.00013 22.2 0.8 0.00021 21.5 0.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFM59144.1 - 0.00035 20.8 0.8 0.00035 20.8 0.8 1.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFM59144.1 - 0.0088 15.9 0.4 0.015 15.2 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KFM59144.1 - 0.023 14.8 0.1 0.039 14.1 0.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 KFM59144.1 - 0.032 14.1 0.4 0.057 13.3 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM59144.1 - 0.037 13.9 0.3 0.064 13.1 0.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KFM59144.1 - 0.25 11.5 1.8 6.7 7.0 1.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-H2C2_2 PF13465.6 KFM59145.1 - 2.1e-44 148.0 95.4 1.7e-06 28.2 0.6 14.4 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM59145.1 - 5.6e-40 132.5 114.1 0.0014 19.3 0.5 14.1 14 0 0 14 14 14 12 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM59145.1 - 3.3e-38 128.0 123.6 0.00011 22.4 0.9 14.1 14 0 0 14 14 14 12 Zinc finger, C2H2 type zf-met PF12874.7 KFM59145.1 - 3.8e-18 65.2 99.1 0.0025 18.1 0.3 14.0 14 0 0 14 14 14 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM59145.1 - 6.3e-15 55.0 104.9 0.0011 19.2 1.0 14.4 12 2 2 14 14 13 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM59145.1 - 3.3e-09 36.9 13.4 2.3 8.6 0.0 8.1 5 3 2 7 7 7 4 BolA-like protein DUF2256 PF10013.9 KFM59145.1 - 0.018 15.2 42.4 2.3 8.4 0.1 12.2 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) AARP2CN PF08142.12 KFM59145.1 - 0.091 12.9 2.1 3 8.0 0.1 3.3 3 0 0 3 3 3 0 AARP2CN (NUC121) domain zf-RRPl_C4 PF17026.5 KFM59145.1 - 0.14 12.2 62.7 0.15 12.2 7.9 6.4 1 1 5 6 6 5 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_6 PF13912.6 KFM59145.1 - 0.4 10.7 87.5 0.27 11.3 0.6 13.7 14 0 0 14 14 14 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFM59145.1 - 1 10.1 63.6 0.65 10.8 4.4 7.2 2 2 4 7 7 7 0 zinc-ribbon family zf-MYST PF17772.1 KFM59145.1 - 1.3 8.7 61.1 0.93 9.2 0.1 12.5 6 3 8 14 14 14 0 MYST family zinc finger domain FYVE PF01363.21 KFM59145.1 - 4.2 7.6 75.5 3.9 7.7 17.0 7.8 2 2 6 8 8 8 0 FYVE zinc finger Septin PF00735.18 KFM59146.1 - 1.5e-86 290.2 1.8 1.5e-86 290.2 1.8 1.8 2 0 0 2 2 2 1 Septin Elongin_A PF06881.11 KFM59146.1 - 7.2 7.2 15.6 1.8e+02 2.7 15.6 2.4 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A HTH_Tnp_Tc3_2 PF01498.18 KFM59147.1 - 2.6e-06 27.6 1.4 4e-06 27.0 1.4 1.2 1 0 0 1 1 1 1 Transposase CUTL PF16557.5 KFM59148.1 - 1.9e-16 60.0 0.1 2.9e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 CUT1-like DNA-binding domain of SATB HTH_3 PF01381.22 KFM59148.1 - 0.14 12.2 0.0 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix AMP-binding PF00501.28 KFM59150.1 - 1.1e-17 63.8 0.0 1.1e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KFM59151.1 - 0.026 13.1 0.0 0.032 12.8 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme PQQ_3 PF13570.6 KFM59152.1 - 3.7e-05 24.1 0.0 0.048 14.2 0.0 2.2 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KFM59152.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 PQQ enzyme repeat PQQ_2 PF13360.6 KFM59152.1 - 0.0046 16.6 0.0 0.0046 16.6 0.0 1.0 1 0 0 1 1 1 1 PQQ-like domain V_cholerae_RfbT PF05575.11 KFM59152.1 - 0.029 13.7 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein PQQ_2 PF13360.6 KFM59153.1 - 7.7e-07 28.9 0.0 8.1e-06 25.6 0.1 2.4 3 0 0 3 3 3 1 PQQ-like domain NAC PF01849.18 KFM59154.1 - 4.9e-24 84.1 0.5 2.7e-23 81.7 0.2 2.1 2 0 0 2 2 2 1 NAC domain Gti1_Pac2 PF09729.9 KFM59154.1 - 1.3 9.1 4.3 0.47 10.5 0.9 1.8 2 0 0 2 2 2 0 Gti1/Pac2 family Ribosomal_L23eN PF03939.13 KFM59155.1 - 7.9e-22 77.2 10.0 7.9e-22 77.2 10.0 3.0 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KFM59155.1 - 1.9e-17 63.4 2.4 1.9e-17 63.4 2.4 2.8 2 1 0 2 2 2 1 Ribosomal protein L23 Acyl_transf_1 PF00698.21 KFM59156.1 - 1.9e-62 211.6 0.0 4.1e-62 210.5 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain ketoacyl-synt PF00109.26 KFM59156.1 - 1.5e-47 162.3 0.1 3.1e-47 161.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFM59156.1 - 1.1e-45 155.8 0.0 2.1e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KFM59156.1 - 1.1e-30 106.1 0.0 2.2e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFM59156.1 - 1.2e-21 77.3 0.0 3.5e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 KFM59156.1 - 1.1e-13 51.2 0.0 2.7e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 KFM59156.1 - 8.8e-13 49.5 0.0 3.2e-12 47.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thioesterase PF00975.20 KFM59156.1 - 3e-11 43.9 0.0 7.2e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain ADH_zinc_N PF00107.26 KFM59156.1 - 1.9e-10 40.8 0.0 5.1e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFM59156.1 - 8.7e-06 25.3 0.0 8.4e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 KFM59156.1 - 0.0041 17.4 0.4 0.01 16.2 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site TetR_C_9 PF14514.6 KFM59156.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Tsc35 PF15079.6 KFM59156.1 - 0.096 12.2 0.4 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 Testis-specific protein 35 DUF1604 PF07713.13 KFM59157.1 - 1.4e-34 117.7 3.8 1.4e-34 117.7 3.8 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KFM59157.1 - 6.7e-05 22.7 0.1 0.00017 21.4 0.1 1.7 1 0 0 1 1 1 1 G-patch domain AP3D1 PF06375.11 KFM59157.1 - 0.00029 21.1 10.7 0.00029 21.1 10.7 3.0 3 0 0 3 3 3 1 AP-3 complex subunit delta-1 G-patch_2 PF12656.7 KFM59157.1 - 0.14 12.2 0.3 1.2 9.2 0.0 2.9 2 1 0 2 2 2 0 G-patch domain DDE_1 PF03184.19 KFM59158.1 - 4.4e-11 42.8 0.1 4.8e-11 42.6 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59159.1 - 2.2e-05 25.0 6.9 0.0011 19.5 3.4 2.2 1 1 1 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 KFM59159.1 - 5.1e-05 22.9 1.4 6.3e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59159.1 - 6.3e-05 22.6 0.9 0.00026 20.7 0.2 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM59159.1 - 8.3e-05 22.5 1.4 9.4e-05 22.4 0.5 1.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM59159.1 - 0.0016 18.6 1.5 0.02 15.1 0.3 2.2 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_1 PF11427.8 KFM59159.1 - 0.003 17.4 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Tc3 transposase Sigma70_r4_2 PF08281.12 KFM59159.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Death PF00531.22 KFM59159.1 - 0.0099 16.0 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 1 Death domain Trp_repressor PF01371.19 KFM59159.1 - 0.038 14.1 0.1 0.089 12.9 0.0 1.6 2 0 0 2 2 2 0 Trp repressor protein HTH_11 PF08279.12 KFM59159.1 - 0.11 12.5 0.9 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 HTH domain HTH_31 PF13560.6 KFM59159.1 - 0.48 10.8 4.3 0.38 11.1 1.3 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain FEZ PF07763.13 KFM59160.1 - 2.3e-47 161.8 1.9 3.3e-47 161.3 1.9 1.2 1 0 0 1 1 1 1 FEZ-like protein DUF5102 PF17104.5 KFM59160.1 - 0.015 15.4 1.2 0.015 15.4 1.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) UQ_con PF00179.26 KFM59161.1 - 4.7e-35 120.3 0.1 5.5e-35 120.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFM59161.1 - 0.0038 17.1 0.1 0.008 16.0 0.0 1.5 1 1 1 2 2 2 1 UEV domain Ion_trans PF00520.31 KFM59164.1 - 1.6e-09 37.3 0.0 2.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFM59164.1 - 6.5e-07 29.2 1.5 1e-06 28.6 1.5 1.3 1 0 0 1 1 1 1 Ion channel PGPGW PF09656.10 KFM59164.1 - 0.69 9.5 4.0 1.2 8.7 4.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) DDE_3 PF13358.6 KFM59165.1 - 5e-16 58.8 0.1 5.8e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59165.1 - 7.3e-16 58.2 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM59165.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59165.1 - 0.0022 17.7 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59165.1 - 0.015 15.4 0.1 0.065 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM59165.1 - 0.035 14.1 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix BTB_2 PF02214.22 KFM59166.1 - 0.013 15.8 1.1 0.032 14.6 0.1 1.9 2 0 0 2 2 2 0 BTB/POZ domain Rep_fac_C PF08542.11 KFM59168.1 - 5.2e-17 62.0 0.1 1.4e-16 60.7 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFM59168.1 - 8.8e-17 61.8 0.0 1.5e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFM59168.1 - 4.2e-14 52.6 0.0 3.4e-11 43.2 0.1 2.5 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_24 PF13479.6 KFM59168.1 - 2e-06 27.6 0.0 4.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM59168.1 - 3.7e-06 27.4 0.0 0.0004 20.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KFM59168.1 - 3.2e-05 23.7 0.0 6.7e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KFM59168.1 - 0.0001 22.5 0.1 0.00046 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA C-terminal domain AAA_11 PF13086.6 KFM59168.1 - 0.00039 20.3 0.1 0.0023 17.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KFM59168.1 - 0.0004 20.7 0.0 0.015 15.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM59168.1 - 0.0035 17.3 0.0 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFM59168.1 - 0.0041 16.5 0.0 0.061 12.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KFM59168.1 - 0.007 15.7 0.1 0.094 11.9 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFM59168.1 - 0.0083 16.1 0.0 0.024 14.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KFM59168.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KFM59168.1 - 0.018 15.3 0.0 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFM59168.1 - 0.019 15.4 0.0 0.21 12.0 0.0 2.5 2 1 1 3 3 3 0 RNA helicase AAA_18 PF13238.6 KFM59168.1 - 0.019 15.5 0.0 0.053 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFM59168.1 - 0.025 14.9 0.1 0.28 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFM59168.1 - 0.031 13.4 0.0 0.082 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 KFM59168.1 - 0.032 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_3 PF07726.11 KFM59168.1 - 0.069 13.0 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFM59168.1 - 0.1 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 KFM59168.1 - 0.14 11.5 0.0 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 KFM59168.1 - 0.14 11.6 0.0 9.4 5.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM59169.1 - 7.7e-15 54.9 0.4 1.4e-14 54.0 0.4 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59169.1 - 4.3e-08 33.0 0.0 9.3e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM59169.1 - 0.0011 19.0 0.5 1.1 9.4 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM59169.1 - 0.0043 17.2 1.2 2.7 8.2 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 KFM59169.1 - 0.011 15.5 2.6 4.2 7.3 0.0 3.2 2 1 0 2 2 2 0 Homeodomain-like domain HTH_22 PF13309.6 KFM59169.1 - 0.095 12.8 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_32 PF13565.6 KFM59169.1 - 0.18 12.5 2.6 1.5 9.5 0.7 2.7 2 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59170.1 - 1.8e-16 60.1 2.2 4.1e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59170.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM59171.1 - 4.7e-16 58.9 0.1 7.1e-15 55.0 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59171.1 - 6.8e-16 58.3 6.5 1.6e-15 57.1 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM59171.1 - 8.9e-05 22.2 0.0 0.004 16.9 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59171.1 - 0.0005 20.6 2.1 0.0005 20.6 2.1 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59171.1 - 0.0017 18.4 0.1 0.0075 16.4 0.1 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM59171.1 - 0.0027 17.7 2.0 0.004 17.1 0.2 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 KFM59171.1 - 0.0031 17.6 0.0 0.0069 16.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 KFM59171.1 - 0.036 13.8 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM59171.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Tc3 transposase PH PF00169.29 KFM59172.1 - 4.8e-12 46.3 0.0 1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF3694 PF12473.8 KFM59172.1 - 1.3e-08 35.6 0.0 2.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein PH_11 PF15413.6 KFM59172.1 - 0.0041 17.5 0.6 0.021 15.2 0.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KFM59172.1 - 0.034 14.5 0.1 0.19 12.1 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Transcrip_reg PF01709.20 KFM59174.1 - 8.9e-56 189.0 1.7 1e-55 188.8 1.7 1.0 1 0 0 1 1 1 1 Transcriptional regulator MA3 PF02847.17 KFM59175.1 - 2.8e-25 88.5 2.2 2.8e-25 88.5 2.2 3.2 5 0 0 5 5 5 1 MA3 domain MIF4G PF02854.19 KFM59175.1 - 4.1e-19 69.1 10.4 4.1e-19 69.1 10.4 3.4 4 0 0 4 4 4 2 MIF4G domain DUF3819 PF12842.7 KFM59175.1 - 0.064 13.2 1.5 0.11 12.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3819) LAP1C PF05609.12 KFM59175.1 - 1.8 7.6 18.3 0.018 14.2 7.8 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) RNR_N PF08343.10 KFM59177.1 - 0.0096 15.9 0.3 0.024 14.7 0.1 1.7 1 1 0 2 2 2 1 Ribonucleotide reductase N-terminal Phytochelatin_C PF09328.10 KFM59177.1 - 0.94 8.8 4.2 4 6.7 4.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1984) Tim29 PF10171.9 KFM59179.1 - 0.042 13.3 0.5 0.044 13.3 0.5 1.0 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Cohesin_load PF10345.9 KFM59181.1 - 3e-94 316.6 10.6 3.3e-94 316.5 10.6 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 KFM59181.1 - 9.1e-05 22.7 10.4 2.9 8.2 0.2 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM59181.1 - 0.0005 19.5 0.1 0.0005 19.5 0.1 3.8 2 2 3 5 5 5 1 MalT-like TPR region TPR_8 PF13181.6 KFM59181.1 - 0.0013 18.8 6.0 18 5.9 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 KFM59181.1 - 0.014 15.1 0.1 0.04 13.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 KFM59181.1 - 0.17 12.5 1.0 2.4 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RNase_H PF00075.24 KFM59182.1 - 0.0079 16.4 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 RNase H DUF2719 PF10891.8 KFM59182.1 - 0.02 14.8 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) Cohesin_load PF10345.9 KFM59183.1 - 3e-17 62.3 0.6 3.6e-17 62.1 0.6 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 KFM59183.1 - 0.032 14.5 0.3 0.091 13.1 0.1 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM59183.1 - 0.14 12.5 0.1 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat EI24 PF07264.11 KFM59184.1 - 2.9e-13 50.4 15.7 2.9e-13 50.4 15.7 1.5 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) YEATS PF03366.16 KFM59185.1 - 1.4e-32 111.5 1.1 2.3e-32 110.8 1.1 1.3 1 0 0 1 1 1 1 YEATS family FapA PF03961.13 KFM59185.1 - 0.014 14.0 2.2 0.018 13.7 2.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PKcGMP_CC PF16808.5 KFM59185.1 - 0.048 13.5 4.5 0.29 11.0 2.2 2.2 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DivIC PF04977.15 KFM59185.1 - 0.082 12.7 5.0 0.14 12.0 5.0 1.4 1 0 0 1 1 1 0 Septum formation initiator Atg14 PF10186.9 KFM59185.1 - 0.18 10.9 4.2 0.23 10.5 4.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Hormone_recep PF00104.30 KFM59186.1 - 1.6e-05 24.6 0.0 2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFM59187.1 - 1.6e-16 60.5 5.8 1.6e-16 60.5 5.8 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) HTH_Tnp_Tc3_2 PF01498.18 KFM59189.1 - 2.1e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59189.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SNF2_N PF00176.23 KFM59190.1 - 9.7e-62 208.7 0.7 2e-61 207.7 0.7 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM59190.1 - 7e-16 58.5 0.0 2.7e-15 56.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM59190.1 - 7.6e-11 42.3 0.0 1.8e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rad54_N PF08658.10 KFM59190.1 - 1.8e-07 31.5 0.2 8.3e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Rad54 N terminal HDA2-3 PF11496.8 KFM59190.1 - 2.4e-07 30.2 0.2 1.1e-06 28.1 0.2 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KFM59190.1 - 0.091 12.4 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 SWI2/SNF2 ATPase HTH_Tnp_Tc3_2 PF01498.18 KFM59191.1 - 2.7e-16 59.5 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59191.1 - 1e-13 51.2 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59191.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59191.1 - 0.0023 17.7 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59191.1 - 1.8 9.2 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain AA_permease PF00324.21 KFM59192.1 - 1.1e-36 126.5 19.7 1.2e-36 126.4 19.7 1.0 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFM59193.1 - 2.3e-135 452.0 0.3 2.6e-135 451.8 0.3 1.0 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 KFM59193.1 - 3.9e-43 147.8 10.0 4.7e-43 147.5 10.0 1.1 1 0 0 1 1 1 1 Amino acid permease NDK PF00334.19 KFM59194.1 - 1.8e-26 92.8 0.1 1.4e-17 64.0 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Dpy-30 PF05186.13 KFM59194.1 - 1.8e-16 59.6 0.2 3.4e-16 58.7 0.2 1.5 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 KFM59194.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF3263 PF11662.8 KFM59194.1 - 0.093 12.6 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) DUF758 PF05527.11 KFM59195.1 - 3.2e-34 118.5 0.2 3.5e-34 118.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) DUF758 PF05527.11 KFM59196.1 - 2.5e-09 37.4 0.0 2.6e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Pro_isomerase PF00160.21 KFM59197.1 - 2.7e-50 170.7 0.3 3e-50 170.6 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD OAR PF03826.17 KFM59199.1 - 1.8e-08 33.9 0.4 1.8e-08 33.9 0.4 1.7 2 0 0 2 2 2 1 OAR domain HTH_Tnp_Tc3_2 PF01498.18 KFM59200.1 - 2e-16 60.0 2.2 4.4e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59200.1 - 9.4e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_12 PF13424.6 KFM59201.1 - 5.7e-52 173.9 41.5 2.1e-12 47.2 0.7 5.3 3 1 4 7 7 7 7 Tetratricopeptide repeat GoLoco PF02188.17 KFM59201.1 - 1.4e-38 129.9 38.9 9.9e-11 40.9 5.7 4.4 4 0 0 4 4 4 4 GoLoco motif TPR_1 PF00515.28 KFM59201.1 - 1.6e-34 116.3 30.0 0.0002 21.0 0.2 9.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFM59201.1 - 1.2e-32 109.5 18.4 7.4e-05 22.5 0.1 8.7 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFM59201.1 - 3.6e-25 86.0 23.9 0.00035 20.5 0.1 9.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFM59201.1 - 1.1e-20 72.8 18.3 0.0089 15.9 0.1 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFM59201.1 - 7.1e-20 69.5 20.5 0.076 13.3 0.8 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM59201.1 - 2.6e-10 40.2 4.3 3.8e-05 23.2 6.5 2.3 2 0 0 2 2 2 2 MalT-like TPR region Rapsyn_N PF10579.9 KFM59201.1 - 5.7e-09 36.0 1.4 0.55 10.4 0.0 5.6 4 2 1 6 6 6 3 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.6 KFM59201.1 - 2.2e-08 34.2 0.7 28 5.9 0.0 7.5 5 2 3 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM59201.1 - 5.3e-07 30.2 11.0 0.012 16.2 0.2 6.6 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFM59201.1 - 6.7e-07 29.3 0.0 1.2 10.0 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM59201.1 - 4.2e-05 23.6 9.2 7.8 7.1 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM59201.1 - 0.0001 22.7 2.5 4 8.0 0.1 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM59201.1 - 0.00091 18.9 25.3 2.2 8.1 0.8 8.0 7 1 1 8 8 8 2 TPR repeat ANAPC5 PF12862.7 KFM59201.1 - 0.0036 17.3 1.1 1.4 9.0 0.0 3.7 3 1 2 5 5 4 1 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 KFM59201.1 - 0.0039 17.7 2.8 39 5.2 0.1 6.5 7 1 0 7 7 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 KFM59201.1 - 0.1 12.7 5.4 2 8.5 0.1 4.3 2 2 3 5 5 5 0 Domain of Unknown Function (DUF3856) Mt_ATP-synt_B PF05405.14 KFM59203.1 - 4.8e-43 146.6 7.3 7.5e-43 146.0 7.3 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) JSRP PF15312.6 KFM59203.1 - 0.062 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Flot PF15975.5 KFM59203.1 - 0.24 11.6 3.2 0.38 10.9 1.1 2.1 2 0 0 2 2 2 0 Flotillin GerPC PF10737.9 KFM59203.1 - 0.4 10.7 6.5 0.36 10.9 5.3 1.6 2 0 0 2 2 2 0 Spore germination protein GerPC UFC1 PF08694.11 KFM59205.1 - 1.1e-85 284.9 0.3 1.3e-85 284.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 SLATT_5 PF18160.1 KFM59205.1 - 0.0079 15.5 0.1 0.01 15.2 0.1 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 RWD PF05773.22 KFM59205.1 - 0.0087 16.3 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.26 KFM59205.1 - 0.015 14.9 0.2 0.038 13.6 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Forkhead PF00250.18 KFM59206.1 - 4.4e-27 94.2 0.3 1e-26 93.0 0.0 1.8 2 0 0 2 2 2 1 Forkhead domain DUF5056 PF16479.5 KFM59207.1 - 0.029 14.6 0.1 0.049 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) DUF5336 PF17270.2 KFM59207.1 - 0.1 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) HTH_Tnp_Tc3_2 PF01498.18 KFM59209.1 - 2.5e-16 59.7 2.6 4.9e-16 58.7 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59209.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2 PF00096.26 KFM59210.1 - 2.4e-22 78.1 91.4 0.00063 20.1 5.3 10.6 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59210.1 - 1.5e-20 72.1 83.6 0.0039 17.9 1.7 10.6 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM59210.1 - 5.6e-14 51.8 79.5 1.2e-08 35.0 1.2 12.0 13 0 0 13 13 12 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM59210.1 - 1.3e-08 34.9 50.1 0.019 15.2 2.2 10.2 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM59210.1 - 5.4e-06 26.3 62.4 0.00031 20.7 0.2 9.9 10 0 0 10 10 10 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM59210.1 - 0.00021 21.0 9.1 0.00068 19.3 3.5 8.2 8 1 0 8 8 7 3 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM59210.1 - 0.0028 17.9 3.6 0.0028 17.9 3.6 6.7 6 0 0 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFM59210.1 - 0.017 15.5 42.8 2.3 8.7 1.3 9.3 9 0 0 9 9 9 0 Zinc-finger of C2H2 type HTH_5 PF01022.20 KFM59210.1 - 0.16 11.9 0.4 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family zf-C2H2_8 PF15909.5 KFM59210.1 - 0.19 12.0 35.9 0.17 12.2 0.6 6.6 6 1 1 7 7 7 0 C2H2-type zinc ribbon CpXC PF14353.6 KFM59210.1 - 0.96 9.5 19.1 1.3 9.1 0.2 5.3 4 1 1 5 5 5 0 CpXC protein Acetyltransf_CG PF14542.6 KFM59211.1 - 1.6e-21 76.2 0.0 2e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 KFM59211.1 - 6.1e-05 23.0 0.0 0.00012 22.0 0.0 1.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM59211.1 - 0.00063 20.0 0.0 0.00072 19.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM59211.1 - 0.051 14.0 0.0 0.054 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_Tnp_Tc3_2 PF01498.18 KFM59212.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59212.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59212.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59212.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59212.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain FA_hydroxylase PF04116.13 KFM59213.1 - 5e-28 98.1 11.4 5e-28 98.1 11.4 2.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily PHD PF00628.29 KFM59214.1 - 4e-07 29.8 8.6 6.8e-07 29.1 7.2 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFM59214.1 - 8.2e-07 28.5 1.2 1.9e-06 27.3 1.2 1.6 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.16 KFM59214.1 - 0.015 15.5 2.9 0.024 14.8 2.9 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 KFM59214.1 - 0.016 15.1 2.1 0.016 15.1 2.1 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KFM59214.1 - 1.7 8.8 10.2 3.2 7.9 4.2 3.3 2 1 2 4 4 4 0 PHD-finger Ets PF00178.22 KFM59216.1 - 1.3e-28 99.2 0.0 2.9e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFM59216.1 - 4.5e-15 55.4 0.8 8.4e-15 54.5 0.8 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Arb2 PF09757.9 KFM59216.1 - 0.16 11.1 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 Arb2 domain Syntaxin_2 PF14523.6 KFM59217.1 - 1.4e-05 25.4 0.0 1.7e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Syntaxin-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM59218.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59218.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59218.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59218.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59218.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain MADF_DNA_bdg PF10545.9 KFM59219.1 - 0.00016 21.9 0.4 0.00023 21.4 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3979 PF13141.6 KFM59221.1 - 0.034 14.4 0.6 0.05 13.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) HTH_Tnp_Tc3_2 PF01498.18 KFM59222.1 - 2.6e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59222.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59223.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59223.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59223.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59223.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59223.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM59224.1 - 4.9e-16 58.8 0.1 5.7e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59224.1 - 7.7e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM59224.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59224.1 - 0.0024 17.6 0.1 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59224.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM59224.1 - 0.034 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix zf-C2H2_4 PF13894.6 KFM59225.1 - 0.0012 19.5 2.5 0.0032 18.2 0.2 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM59225.1 - 0.0016 18.8 0.1 0.0016 18.8 0.1 2.7 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM59225.1 - 0.18 11.8 0.5 0.46 10.5 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM59225.1 - 0.53 10.6 0.0 0.53 10.6 0.0 2.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HTH_Tnp_Tc3_2 PF01498.18 KFM59226.1 - 1.8e-16 60.1 2.2 4.1e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59226.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KFM59227.1 - 1.9e-17 63.4 0.1 3.2e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM59227.1 - 7.2e-12 45.2 0.3 1.6e-11 44.1 0.3 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM59227.1 - 0.0042 16.8 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM59228.1 - 7.5e-06 25.8 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease C1_2 PF03107.16 KFM59229.1 - 0.03 14.6 2.3 0.11 12.8 2.3 2.0 1 0 0 1 1 1 0 C1 domain Rubredoxin PF00301.20 KFM59229.1 - 2.5 8.2 4.5 72 3.5 0.0 2.8 2 0 0 2 2 2 0 Rubredoxin EF-hand_11 PF08976.11 KFM59230.1 - 3.4e-06 27.9 0.1 4.7e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain SirA PF10747.9 KFM59230.1 - 0.022 15.1 0.7 0.027 14.8 0.7 1.3 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA Biopterin_H PF00351.21 KFM59231.1 - 1.1e-176 586.7 0.0 1.4e-176 586.4 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KFM59231.1 - 4.5e-06 26.3 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 ACT domain RT_RNaseH_2 PF17919.1 KFM59232.1 - 2.6e-39 133.3 1.6 3.8e-39 132.8 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM59232.1 - 4.8e-37 126.4 0.1 2.5e-36 124.2 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM59232.1 - 5.1e-31 107.9 0.1 1.2e-30 106.7 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM59232.1 - 1.7e-20 73.4 0.0 6.7e-20 71.5 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM59232.1 - 1.1e-18 67.0 0.0 2.9e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 KFM59232.1 - 2.8e-12 47.0 0.0 7.7e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM59232.1 - 5.1e-09 36.7 0.0 1.5e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KFM59232.1 - 2.9e-05 23.9 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 KFM59232.1 - 0.0017 18.6 0.0 0.0017 18.6 0.0 4.2 4 1 1 5 5 4 1 Retrotransposon gag protein Spuma_A9PTase PF03539.14 KFM59232.1 - 0.0019 18.3 0.0 0.0054 16.9 0.0 1.8 1 0 0 1 1 1 1 Spumavirus aspartic protease (A9) Apolipoprotein PF01442.18 KFM59232.1 - 0.003 17.5 29.9 0.014 15.2 24.1 2.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain zf-H2C2 PF09337.10 KFM59232.1 - 0.0056 16.9 0.0 0.024 14.9 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger zf-CCHC PF00098.23 KFM59232.1 - 0.018 15.1 2.9 0.056 13.5 2.9 1.9 1 0 0 1 1 1 0 Zinc knuckle rve_3 PF13683.6 KFM59232.1 - 0.018 14.8 0.0 0.14 11.9 0.0 2.7 1 0 0 1 1 1 0 Integrase core domain Eno-Rase_FAD_bd PF07055.12 KFM59232.1 - 0.22 12.0 2.6 1.1 9.7 2.6 2.3 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain V_ATPase_I PF01496.19 KFM59232.1 - 1.2 7.0 11.3 2.1 6.2 11.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.11 KFM59232.1 - 2.8 5.8 10.1 6.5 4.6 10.1 1.6 1 0 0 1 1 1 0 Prominin Nup88 PF10168.9 KFM59232.1 - 6.3 4.5 18.3 13 3.4 18.3 1.5 1 0 0 1 1 1 0 Nuclear pore component zf-C2H2_12 PF18658.1 KFM59233.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger C2H2-type OrsD PF12013.8 KFM59233.1 - 0.022 15.2 0.2 0.032 14.7 0.2 1.2 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D BRCA-2_OB3 PF09104.10 KFM59233.1 - 0.075 12.7 0.5 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DNA_pol_D_N PF18018.1 KFM59233.1 - 0.085 13.0 0.1 0.098 12.8 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Telomere_reg-2 PF10193.9 KFM59235.1 - 2.8e-31 108.2 1.1 1.1e-30 106.3 0.5 2.4 2 0 0 2 2 2 1 Telomere length regulation protein Bac_rhodopsin PF01036.18 KFM59235.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein adh_short PF00106.25 KFM59238.1 - 5.1e-50 169.6 0.1 6.9e-50 169.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM59238.1 - 2.5e-36 125.4 0.3 3.1e-36 125.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM59238.1 - 2.9e-09 37.1 0.0 4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM59238.1 - 0.0021 17.6 0.1 0.009 15.5 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KFM59238.1 - 0.005 16.5 0.0 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DUF1776 PF08643.10 KFM59238.1 - 0.0063 15.9 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 KFM59238.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 KFM59238.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KFM59238.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFM59238.1 - 0.12 11.5 0.0 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein HPIH PF13323.6 KFM59239.1 - 0.22 11.4 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain with HPIH motif DDE_3 PF13358.6 KFM59240.1 - 9.6e-16 57.8 0.1 1.1e-14 54.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59240.1 - 1.4e-10 41.2 1.0 2.8e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM59241.1 - 4.8e-16 58.8 3.5 6.1e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59241.1 - 1.3e-13 50.9 0.0 2.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59241.1 - 2.9e-07 30.1 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59241.1 - 0.0029 17.4 0.6 0.008 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59241.1 - 2.2 8.9 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain Big_2 PF02368.18 KFM59242.1 - 0.0092 15.9 6.7 0.18 11.7 0.9 4.4 5 0 0 5 5 5 2 Bacterial Ig-like domain (group 2) CortBP2 PF09727.9 KFM59243.1 - 1.3e-65 220.9 42.1 2.3e-63 213.6 22.7 2.1 2 0 0 2 2 2 2 Cortactin-binding protein-2 CCDC144C PF14915.6 KFM59243.1 - 0.00087 18.5 25.2 0.00087 18.5 25.2 2.1 1 1 1 2 2 2 1 CCDC144C protein coiled-coil region Spc29 PF17082.5 KFM59243.1 - 0.0046 16.8 0.6 0.0046 16.8 0.6 2.6 2 1 1 3 3 3 1 Spindle Pole Component 29 OmpH PF03938.14 KFM59243.1 - 1.9 8.8 32.9 0.19 12.1 5.0 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Lipoprotein_6 PF01441.19 KFM59243.1 - 3.3 7.7 8.4 0.24 11.4 1.8 2.1 2 0 0 2 2 2 0 Lipoprotein APG6_N PF17675.1 KFM59243.1 - 3.8 8.1 50.4 22 5.6 23.9 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 KFM59243.1 - 6.4 6.1 44.4 0.035 13.5 9.9 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding SIP1 PF04938.12 KFM59244.1 - 8.4e-52 176.0 0.0 1e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) HTH_Tnp_Tc3_2 PF01498.18 KFM59245.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59245.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM59246.1 - 1.5e-06 28.0 0.1 3.8e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM59246.1 - 2.2e-06 27.4 0.0 7.4e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MFS_1 PF07690.16 KFM59247.1 - 1.6e-20 73.3 36.2 1.4e-14 53.8 14.4 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFM59248.1 - 2.4e-19 69.5 20.6 4.5e-19 68.6 20.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM59248.1 - 1.2e-06 27.6 7.7 1.2e-06 27.6 7.7 2.6 2 2 1 3 3 3 1 Sugar (and other) transporter Noggin PF05806.12 KFM59249.1 - 2.6e-37 128.9 13.0 3e-37 128.6 13.0 1.0 1 0 0 1 1 1 1 Noggin MCM PF00493.23 KFM59250.1 - 2.1e-101 337.7 0.0 2.9e-101 337.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFM59250.1 - 3.8e-36 123.7 0.2 6.8e-36 122.9 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KFM59250.1 - 4.2e-18 65.8 1.1 1.1e-17 64.5 1.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 KFM59250.1 - 6e-17 62.4 14.8 6e-17 62.4 14.8 1.9 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 KFM59250.1 - 3e-09 36.5 0.0 5e-07 29.3 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFM59250.1 - 1.1e-05 25.4 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFM59250.1 - 0.0001 22.2 0.0 0.00057 19.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MCM_lid PF17855.1 KFM59250.1 - 0.0049 17.3 0.1 0.014 15.8 0.1 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain Sigma54_activat PF00158.26 KFM59250.1 - 0.016 14.9 0.0 0.77 9.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KFM59250.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2795 PF11387.8 KFM59250.1 - 0.16 12.2 0.6 0.53 10.5 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) MCM_lid PF17855.1 KFM59251.1 - 4e-08 33.6 2.7 8.8e-08 32.5 0.2 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain AAA_lid_2 PF17863.1 KFM59251.1 - 0.0037 17.1 0.1 0.0078 16.0 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain DUF1548 PF07579.11 KFM59251.1 - 0.036 14.4 0.5 0.05 13.9 0.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) RasGAP PF00616.19 KFM59252.1 - 1.3e-31 110.0 1.3 4.3e-22 78.8 0.1 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 KFM59253.1 - 7e-17 61.9 0.2 1.3e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 PH domain DUF5098 PF17023.5 KFM59253.1 - 0.0077 15.2 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5098) PH_9 PF15410.6 KFM59253.1 - 0.0097 16.3 0.0 0.23 11.8 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain C2 PF00168.30 KFM59253.1 - 0.03 14.6 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 C2 domain SH2 PF00017.24 KFM59254.1 - 3.9e-18 65.3 0.0 9e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFM59254.1 - 2e-09 36.9 0.0 8.2e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFM59254.1 - 2.4e-05 24.1 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM59254.1 - 4e-05 23.2 0.0 7.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH2_2 PF14633.6 KFM59254.1 - 0.013 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 SH2 domain Lon_C PF05362.13 KFM59256.1 - 2.4e-70 236.2 0.2 6.4e-70 234.9 0.0 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KFM59256.1 - 9.5e-25 87.5 0.0 2e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KFM59256.1 - 4.5e-09 36.7 0.0 1.6e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFM59256.1 - 4e-08 33.3 0.0 7.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFM59256.1 - 2.4e-07 30.7 0.0 4.4e-06 26.5 0.0 2.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 KFM59256.1 - 1.7e-06 27.2 0.0 3.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain ChlI PF13541.6 KFM59256.1 - 5.1e-06 26.3 1.6 1.3e-05 25.0 0.1 2.4 2 1 1 3 3 3 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KFM59256.1 - 7.8e-06 26.4 0.1 5.5e-05 23.6 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFM59256.1 - 5.9e-05 23.4 0.2 0.0021 18.4 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.6 KFM59256.1 - 0.00033 20.7 0.1 0.0012 18.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KFM59256.1 - 0.0017 18.7 0.0 0.0054 17.1 0.0 1.9 2 0 0 2 2 1 1 RNA helicase RsgA_GTPase PF03193.16 KFM59256.1 - 0.0021 18.0 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KFM59256.1 - 0.0024 18.4 0.0 0.014 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KFM59256.1 - 0.0026 17.0 0.7 0.0057 15.9 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 KFM59256.1 - 0.0045 16.9 0.0 0.029 14.3 0.0 2.3 1 1 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.17 KFM59256.1 - 0.0049 16.6 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_23 PF13476.6 KFM59256.1 - 0.005 17.4 2.3 0.27 11.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KFM59256.1 - 0.0089 15.9 0.1 0.13 12.2 0.0 2.5 1 1 1 2 2 2 1 NTPase AAA_33 PF13671.6 KFM59256.1 - 0.012 15.7 0.3 0.034 14.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KFM59256.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KFM59256.1 - 0.016 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain MCM PF00493.23 KFM59256.1 - 0.028 13.5 0.0 0.067 12.3 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain TsaE PF02367.17 KFM59256.1 - 0.028 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KFM59256.1 - 0.038 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.9 KFM59256.1 - 0.039 14.0 0.2 0.48 10.5 0.3 2.5 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Torsin PF06309.11 KFM59256.1 - 0.041 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_7 PF12775.7 KFM59256.1 - 0.041 13.4 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KFM59256.1 - 0.048 13.6 0.1 0.25 11.2 0.0 2.2 3 0 0 3 3 2 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 KFM59256.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.25 KFM59256.1 - 0.074 12.7 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.17 KFM59256.1 - 0.08 12.0 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KFM59256.1 - 0.083 12.6 0.2 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM59256.1 - 0.084 13.4 0.0 0.32 11.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 KFM59256.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Phage_XkdX PF09693.10 KFM59256.1 - 0.12 12.5 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) AAA_17 PF13207.6 KFM59256.1 - 0.13 12.7 0.7 0.64 10.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 KFM59256.1 - 0.16 11.9 6.5 4.4 7.2 0.0 3.5 2 1 1 4 4 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFM59256.1 - 0.16 12.3 0.1 1.1 9.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain C2 PF00168.30 KFM59257.1 - 4.4e-51 171.5 0.1 2.1e-24 85.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 KFM59257.1 - 0.00094 18.8 0.0 0.0092 15.6 0.0 2.2 2 0 0 2 2 2 1 CEP76 C2 domain Cadherin_C_2 PF16492.5 KFM59257.1 - 0.065 14.0 0.0 0.23 12.2 0.0 2.1 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal PTEN_C2 PF10409.9 KFM59257.1 - 0.073 12.8 0.1 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein Coatomer_E PF04733.14 KFM59258.1 - 2.2e-110 368.7 3.9 2.5e-110 368.5 3.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KFM59258.1 - 1.7e-06 28.4 3.9 0.00034 21.1 0.8 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM59258.1 - 1.3e-05 24.8 1.7 0.00043 20.0 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM59258.1 - 0.00017 22.2 0.4 0.0012 19.5 0.1 2.6 2 1 1 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM59258.1 - 0.00019 21.6 5.1 0.064 13.5 0.2 2.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFM59258.1 - 0.00021 21.2 0.2 0.00021 21.2 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM59258.1 - 0.0013 19.0 0.3 0.0061 16.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM59258.1 - 0.002 18.7 0.1 0.0053 17.4 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM59258.1 - 0.0069 16.3 0.4 0.042 13.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4919 PF16266.5 KFM59258.1 - 0.018 15.0 0.4 0.041 13.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) Glyco_transf_64 PF09258.10 KFM59258.1 - 0.032 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain Com_YlbF PF06133.11 KFM59258.1 - 0.092 13.4 0.2 0.092 13.4 0.2 3.3 3 1 1 4 4 4 0 Control of competence regulator ComK, YlbF/YmcA TPR_10 PF13374.6 KFM59258.1 - 0.22 11.5 1.6 0.31 11.0 0.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4528 PF15031.6 KFM59259.1 - 1.6e-56 189.8 0.8 1.8e-56 189.6 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4528) KH_1 PF00013.29 KFM59260.1 - 2.1e-44 149.2 9.4 2.7e-16 59.1 2.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFM59260.1 - 1.2e-18 66.7 2.7 1e-05 25.2 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFM59260.1 - 7.3e-10 38.8 2.5 0.055 13.6 0.0 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.6 KFM59260.1 - 2.9e-07 30.2 1.4 0.06 13.2 0.0 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KFM59260.1 - 0.027 14.4 0.0 0.16 12.0 0.0 2.1 3 0 0 3 3 3 0 KH-like RNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM59261.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59261.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59262.1 - 1.1e-10 41.7 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Transposase Bmt2 PF11968.8 KFM59263.1 - 1.9e-12 47.5 0.1 1.1e-11 45.0 0.1 1.9 1 1 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_11 PF08241.12 KFM59263.1 - 0.00017 22.2 0.0 0.00035 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM59263.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM59263.1 - 0.0016 18.3 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM59263.1 - 0.0036 18.0 0.0 0.0082 16.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM59263.1 - 0.029 15.1 0.0 0.081 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Sec63 PF02889.16 KFM59263.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Sec63 Brl domain FMO-like PF00743.19 KFM59264.1 - 2e-73 247.6 0.3 2.3e-73 247.5 0.3 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM59264.1 - 1.4e-15 57.3 0.0 1.9e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM59264.1 - 7.7e-11 41.8 0.0 9.8e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM59264.1 - 1.2e-09 37.8 0.1 4.5e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFM59264.1 - 6.4e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFM59264.1 - 0.0004 19.7 0.1 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KFM59264.1 - 0.0012 18.9 0.1 0.03 14.3 0.1 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KFM59264.1 - 0.0036 16.1 0.1 0.0072 15.1 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KFM59264.1 - 0.033 13.8 0.0 2.9 7.4 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFM59264.1 - 0.097 12.0 0.1 0.36 10.1 0.0 1.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M17_N PF02789.17 KFM59264.1 - 0.099 12.5 0.3 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Pyr_redox PF00070.27 KFM59264.1 - 0.16 12.6 1.6 1.9 9.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DSPn PF14671.6 KFM59265.1 - 3.7e-60 202.4 3.3 5.9e-59 198.5 2.2 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFM59265.1 - 1.1e-14 54.3 0.0 2.8e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFM59265.1 - 6.8e-07 29.5 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFM59265.1 - 2e-05 24.3 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM59265.1 - 0.019 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family HTH_Tnp_Tc5 PF03221.16 KFM59266.1 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CBM49 PF09478.10 KFM59266.1 - 0.083 13.2 0.5 0.17 12.2 0.5 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 Phospho_p8 PF10195.9 KFM59267.1 - 2.7e-27 95.0 7.9 3.3e-27 94.8 7.9 1.1 1 0 0 1 1 1 1 DNA-binding nuclear phosphoprotein p8 PAN_1 PF00024.26 KFM59268.1 - 1.4e-18 66.6 18.5 1.2e-09 37.9 6.1 3.5 3 0 0 3 3 3 3 PAN domain PAN_3 PF08277.12 KFM59268.1 - 1.5 8.7 10.8 4.5 7.2 1.8 3.3 3 0 0 3 3 3 0 PAN-like domain PAN_4 PF14295.6 KFM59268.1 - 4 7.4 10.8 5.7 6.9 0.1 3.1 3 0 0 3 3 3 0 PAN domain DDE_1 PF03184.19 KFM59269.1 - 1.3e-15 57.5 0.2 2.2e-15 56.8 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM59269.1 - 4.1e-12 45.9 0.4 9.3e-12 44.8 0.4 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM59269.1 - 0.042 13.6 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 KFM59269.1 - 0.14 12.5 0.1 0.34 11.2 0.1 1.7 1 0 0 1 1 1 0 Transposase DUF3372 PF11852.8 KFM59269.1 - 0.14 11.6 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) C2 PF00168.30 KFM59270.1 - 4.2e-12 46.3 0.0 5.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain EI24 PF07264.11 KFM59272.1 - 0.0094 16.2 6.9 0.014 15.6 6.9 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) MARVEL PF01284.23 KFM59272.1 - 0.015 15.3 9.1 0.019 15.0 9.1 1.1 1 0 0 1 1 1 0 Membrane-associating domain Phage_holin_3_6 PF07332.11 KFM59272.1 - 0.07 13.2 0.6 0.097 12.7 0.6 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HTH_32 PF13565.6 KFM59274.1 - 0.056 14.1 0.3 0.061 14.0 0.3 1.0 1 0 0 1 1 1 0 Homeodomain-like domain DUF2890 PF11081.8 KFM59275.1 - 0.062 13.4 0.0 0.099 12.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) DNA_methylase PF00145.17 KFM59276.1 - 3e-12 46.5 0.1 3.4e-12 46.4 0.1 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase PrmA PF06325.13 KFM59276.1 - 0.0014 18.0 0.0 0.0015 18.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) SOAR PF16533.5 KFM59277.1 - 7.5e-43 144.6 0.5 7.5e-43 144.6 0.5 2.5 2 0 0 2 2 2 1 STIM1 Orai1-activating region SAM_2 PF07647.17 KFM59277.1 - 2.7e-13 49.8 0.2 2e-12 47.1 0.0 2.5 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM59277.1 - 2.2e-09 37.6 0.0 6.3e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KFM59277.1 - 0.007 16.6 0.1 0.038 14.2 0.0 2.3 2 0 0 2 2 2 1 Ste50p, sterile alpha motif DUF4446 PF14584.6 KFM59277.1 - 0.76 9.8 6.6 0.47 10.4 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Sulfatase PF00884.23 KFM59278.1 - 2e-66 224.5 0.0 2.5e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFM59278.1 - 1.2e-05 25.1 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KFM59278.1 - 0.018 15.8 0.0 0.068 13.9 0.0 1.9 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KFM59278.1 - 0.051 13.5 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF229 PF02995.17 KFM59278.1 - 0.14 10.7 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) MAD PF05557.13 KFM59279.1 - 0.002 16.6 9.3 0.002 16.6 9.3 2.0 1 1 1 2 2 2 1 Mitotic checkpoint protein Tup_N PF08581.10 KFM59279.1 - 0.0078 16.5 10.2 0.0078 16.5 10.2 2.2 1 1 1 2 2 2 1 Tup N-terminal TPR_MLP1_2 PF07926.12 KFM59279.1 - 0.068 13.2 23.5 0.058 13.5 8.6 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 KFM59279.1 - 0.086 12.9 20.7 0.033 14.3 5.9 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Tropomyosin_1 PF12718.7 KFM59279.1 - 0.097 12.8 26.8 0.12 12.5 26.8 1.1 1 0 0 1 1 1 0 Tropomyosin like PEP-utilisers_N PF05524.13 KFM59279.1 - 0.099 12.8 7.7 1.1 9.4 7.7 2.0 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Csm1_N PF18504.1 KFM59279.1 - 0.15 12.4 22.0 0.36 11.2 6.2 2.5 1 1 0 2 2 2 0 Csm1 N-terminal domain AKNA PF12443.8 KFM59279.1 - 0.17 12.6 15.5 0.72 10.5 3.7 2.3 1 1 1 2 2 2 0 AT-hook-containing transcription factor TLE_N PF03920.15 KFM59279.1 - 0.17 12.0 10.7 0.05 13.7 2.0 2.3 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain ERM PF00769.19 KFM59279.1 - 0.2 11.4 27.2 0.33 10.7 27.2 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Fez1 PF06818.15 KFM59279.1 - 0.21 12.0 22.9 0.23 11.9 22.9 1.1 1 0 0 1 1 1 0 Fez1 LRRFIP PF09738.9 KFM59279.1 - 0.3 10.5 25.0 0.76 9.2 8.3 2.0 1 1 1 2 2 2 0 LRRFIP family DivIVA PF05103.13 KFM59279.1 - 0.32 11.1 18.0 0.7 10.0 18.0 1.7 1 1 0 1 1 1 0 DivIVA protein YabA PF06156.13 KFM59279.1 - 0.33 11.6 19.1 1 10.1 9.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA IFT20 PF14931.6 KFM59279.1 - 0.38 10.9 21.5 0.2 11.8 6.1 2.3 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF1664 PF07889.12 KFM59279.1 - 0.39 10.8 11.2 0.075 13.1 5.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 KFM59279.1 - 0.58 9.5 26.3 2 7.7 26.1 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2730 PF10805.8 KFM59279.1 - 0.58 10.3 9.0 0.24 11.5 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Mod_r PF07200.13 KFM59279.1 - 0.6 10.2 22.2 0.052 13.7 14.4 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.11 KFM59279.1 - 0.71 10.3 19.2 2 8.9 3.7 3.8 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Fmp27_WPPW PF10359.9 KFM59279.1 - 0.73 8.6 16.5 1.1 8.0 16.5 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ZapB PF06005.12 KFM59279.1 - 0.9 10.0 27.2 0.37 11.3 11.5 2.7 1 1 1 2 2 2 0 Cell division protein ZapB FapA PF03961.13 KFM59279.1 - 0.94 8.0 16.9 1.1 7.8 16.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 KFM59279.1 - 0.99 10.1 23.8 0.31 11.7 5.6 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF745 PF05335.13 KFM59279.1 - 1.1 9.0 14.1 2.1 8.0 13.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) GrpE PF01025.19 KFM59279.1 - 1.2 8.7 22.3 0.56 9.9 7.3 2.1 1 1 1 2 2 2 0 GrpE DUF4047 PF13256.6 KFM59279.1 - 1.3 9.3 13.1 0.34 11.1 6.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) OmpH PF03938.14 KFM59279.1 - 1.4 9.3 25.0 7e+02 0.5 24.9 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 KFM59279.1 - 1.6 9.2 27.3 0.43 11.1 17.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2009 PF09418.10 KFM59279.1 - 1.7 7.7 9.3 2.3 7.2 9.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2009) DUF4446 PF14584.6 KFM59279.1 - 2.3 8.2 16.2 5 7.1 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.19 KFM59279.1 - 2.8 5.8 14.7 3.1 5.6 14.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KFM59279.1 - 2.9 6.7 24.0 5.7 5.7 8.8 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DLP_helical PF18709.1 KFM59279.1 - 3.3 6.8 18.3 1.8 7.7 6.5 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain Borrelia_P83 PF05262.11 KFM59279.1 - 3.7 5.9 20.6 4 5.8 20.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 KFM59279.1 - 3.9 6.7 19.5 6.1 6.1 19.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2205 PF10224.9 KFM59279.1 - 4 7.5 17.6 0.11 12.5 6.1 2.6 1 1 0 2 2 2 0 Short coiled-coil protein HAUS6_N PF14661.6 KFM59279.1 - 4.4 6.8 19.4 1.9 8.0 9.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Dzip-like_N PF13815.6 KFM59279.1 - 4.9 7.2 17.9 5 7.1 5.3 2.3 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Exonuc_VII_L PF02601.15 KFM59279.1 - 5.7 6.4 16.7 6.8 6.2 16.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.13 KFM59279.1 - 8.7 7.0 10.0 8.2 7.1 3.9 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HTH_Tnp_Tc3_2 PF01498.18 KFM59281.1 - 2.6e-16 59.6 2.8 4.9e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59281.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59281.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59281.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59281.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Troponin PF00992.20 KFM59282.1 - 2.7e-44 150.7 17.3 3.4e-44 150.4 17.3 1.1 1 0 0 1 1 1 1 Troponin DUF2845 PF11006.8 KFM59282.1 - 0.04 14.0 0.6 0.077 13.1 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2845) p450 PF00067.22 KFM59284.1 - 2.6e-67 227.6 0.3 3e-67 227.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sushi PF00084.20 KFM59286.1 - 9.4e-14 51.8 19.4 6.9e-06 26.6 1.7 4.2 4 0 0 4 4 4 3 Sushi repeat (SCR repeat) Ephrin_rec_like PF07699.13 KFM59287.1 - 1.8e-07 30.8 11.0 1.8e-06 27.6 5.7 3.2 1 1 1 2 2 2 2 Putative ephrin-receptor like NCD3G PF07562.14 KFM59287.1 - 0.0018 18.2 12.0 0.0039 17.1 2.8 3.1 2 1 1 3 3 3 2 Nine Cysteines Domain of family 3 GPCR RTT107_BRCT_5 PF16770.5 KFM59287.1 - 0.012 15.5 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Complex1_49kDa PF00346.19 KFM59287.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit HypA PF01155.19 KFM59287.1 - 1.6 8.7 5.5 26 4.9 5.5 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RVT_1 PF00078.27 KFM59288.1 - 0.00016 21.2 0.2 0.00062 19.3 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5492 PF17596.2 KFM59288.1 - 2.1 8.7 12.5 0.096 13.0 4.2 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5492) HTH_Tnp_Tc3_2 PF01498.18 KFM59289.1 - 2.7e-16 59.5 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59289.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59289.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59289.1 - 0.0023 17.6 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59289.1 - 1.8 9.2 15.7 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59291.1 - 4.7e-16 58.8 3.5 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59291.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59291.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59291.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59291.1 - 0.029 14.5 0.4 0.089 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM59291.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain MSV199 PF10553.9 KFM59292.1 - 0.019 15.2 3.7 0.028 14.7 3.7 1.2 1 0 0 1 1 1 0 MSV199 domain zf-RING_13 PF17977.1 KFM59294.1 - 0.023 14.8 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain cEGF PF12662.7 KFM59295.1 - 2e-08 34.0 37.1 0.002 18.0 0.3 6.5 5 1 1 6 6 6 4 Complement Clr-like EGF-like EGF_CA PF07645.15 KFM59295.1 - 2.5e-07 30.8 4.0 2.5e-07 30.8 4.0 5.6 3 3 2 5 5 5 1 Calcium-binding EGF domain EGF PF00008.27 KFM59295.1 - 1.4e-06 28.5 59.7 0.00019 21.6 4.3 6.3 5 3 1 6 6 6 4 EGF-like domain hEGF PF12661.7 KFM59295.1 - 3.5e-05 24.2 10.2 0.00013 22.5 3.6 7.4 6 2 1 7 7 7 2 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 KFM59295.1 - 0.0025 18.1 53.8 0.0034 17.7 4.8 5.4 3 1 2 5 5 5 3 Pvs28 EGF domain FXa_inhibition PF14670.6 KFM59295.1 - 0.0055 17.0 1.6 0.0055 17.0 1.6 5.9 2 2 1 4 4 4 2 Coagulation Factor Xa inhibitory site EB PF01683.18 KFM59295.1 - 0.033 14.5 2.8 0.033 14.5 2.8 5.6 5 1 0 5 5 5 0 EB module EGF_3 PF12947.7 KFM59295.1 - 0.4 10.9 60.5 0.32 11.2 8.0 7.1 4 3 2 6 6 6 0 EGF domain Peptidase_M13_N PF05649.13 KFM59296.1 - 3.3e-22 79.7 0.0 3.7e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 SNAP-25 PF00835.19 KFM59297.1 - 1.3e-16 60.6 0.6 2.8e-16 59.5 0.6 1.6 1 0 0 1 1 1 1 SNAP-25 family DUF5089 PF17002.5 KFM59297.1 - 7.7e-06 25.9 5.4 1.9e-05 24.7 5.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) SNARE PF05739.19 KFM59297.1 - 0.0064 16.5 0.7 0.0064 16.5 0.7 3.2 3 1 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.8 KFM59297.1 - 0.034 14.4 6.7 0.039 14.2 0.7 2.5 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Rx_N PF18052.1 KFM59297.1 - 0.15 12.3 4.3 0.8 10.0 0.1 2.5 2 1 0 2 2 2 0 Rx N-terminal domain MCPsignal PF00015.21 KFM59297.1 - 0.35 10.7 8.1 1.3 8.8 1.0 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain XhlA PF10779.9 KFM59297.1 - 0.49 10.6 12.6 0.62 10.3 1.6 3.3 3 0 0 3 3 3 0 Haemolysin XhlA Snapin_Pallidin PF14712.6 KFM59297.1 - 0.54 10.7 10.4 1.2 9.6 1.9 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Sec20 PF03908.13 KFM59297.1 - 0.83 9.6 7.7 0.064 13.2 1.3 2.0 2 0 0 2 2 2 0 Sec20 HIP1_clath_bdg PF16515.5 KFM59297.1 - 1 10.0 10.5 0.24 12.0 2.6 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 KFM59297.1 - 1.1 9.9 8.1 3.8 8.2 0.2 2.7 2 1 1 3 3 3 0 SlyX DUF948 PF06103.11 KFM59297.1 - 1.2 9.5 4.8 2.8 8.3 0.4 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SOAR PF16533.5 KFM59297.1 - 1.2 9.2 7.3 2.8 8.0 0.5 2.9 2 2 0 2 2 2 0 STIM1 Orai1-activating region DUF16 PF01519.16 KFM59297.1 - 1.9 9.0 6.5 17 5.9 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 Acetyltransf_1 PF00583.25 KFM59298.1 - 9.9e-14 51.6 0.1 1.3e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM59298.1 - 4.8e-10 39.5 0.1 6.5e-10 39.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM59298.1 - 9.9e-08 32.3 0.1 1.3e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM59298.1 - 1.5e-07 31.2 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFM59298.1 - 0.00019 21.5 0.0 0.0004 20.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFM59298.1 - 0.014 15.5 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HAT PF02184.16 KFM59299.1 - 9.4e-46 153.4 74.1 2.7e-17 62.4 3.2 13.9 14 0 0 14 14 14 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KFM59299.1 - 1.3e-25 87.9 12.5 0.012 16.3 0.1 10.5 5 2 6 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFM59299.1 - 3.5e-16 59.5 0.0 0.0039 17.7 0.0 6.4 5 1 3 8 8 7 5 Tetratricopeptide repeat Suf PF05843.14 KFM59299.1 - 1e-13 52.0 38.2 1.1e-06 28.8 5.8 6.7 1 1 4 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KFM59299.1 - 2.6e-10 39.9 2.0 0.0016 18.7 0.0 5.4 6 0 0 6 6 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM59299.1 - 5.8e-10 39.6 1.4 0.92 10.2 0.0 7.5 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM59299.1 - 2.2e-07 30.4 18.0 3.7 7.9 0.1 9.6 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM59299.1 - 1.2e-06 28.3 11.9 20 5.7 0.0 9.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFM59299.1 - 2.7e-05 23.6 12.3 1.1 8.3 0.2 6.3 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM59299.1 - 3.1e-05 24.2 6.8 3.5 8.0 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM59299.1 - 0.0001 22.3 4.8 0.53 10.5 0.1 6.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM59299.1 - 0.0001 22.7 15.8 5.9 7.8 0.0 8.6 10 0 0 10 10 10 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFM59299.1 - 0.0014 18.6 29.8 0.12 12.4 3.8 6.7 5 2 1 6 6 6 2 Mad3/BUB1 homology region 1 TPR_7 PF13176.6 KFM59299.1 - 0.0053 16.7 5.8 14 6.0 0.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KFM59299.1 - 0.027 14.5 24.1 0.11 12.6 0.8 6.7 5 1 1 6 6 6 0 U3 small nucleolar RNA-associated protein 6 TPR_11 PF13414.6 KFM59299.1 - 0.61 9.8 7.1 1.4 8.7 0.0 4.6 5 0 0 5 5 5 0 TPR repeat DRY_EERY PF09750.9 KFM59300.1 - 3.2e-29 101.9 0.7 3.2e-29 101.9 0.7 4.6 3 1 0 3 3 3 1 Alternative splicing regulator Surp PF01805.20 KFM59300.1 - 2.8e-27 94.5 1.5 3.5e-13 49.3 0.0 2.6 2 0 0 2 2 2 2 Surp module DDE_3 PF13358.6 KFM59301.1 - 6.7e-16 58.4 0.1 8.2e-15 54.8 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59301.1 - 1.8e-15 56.9 6.5 1.8e-15 56.9 6.5 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 KFM59301.1 - 8.5e-10 38.1 0.6 0.0004 20.1 0.0 4.0 4 0 0 4 4 4 2 Homeodomain-like domain HTH_29 PF13551.6 KFM59301.1 - 3.5e-09 36.5 6.6 1.2e-05 25.2 0.1 3.1 3 0 0 3 3 3 2 Winged helix-turn helix HTH_28 PF13518.6 KFM59301.1 - 8.3e-07 29.0 0.9 0.075 13.2 0.1 3.0 2 0 0 2 2 2 2 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KFM59301.1 - 3.1e-05 23.6 0.1 0.0017 18.0 0.0 2.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_32 PF13565.6 KFM59301.1 - 0.00012 22.6 4.9 0.0009 19.8 1.5 3.9 4 1 0 4 4 4 2 Homeodomain-like domain HTH_7 PF02796.15 KFM59301.1 - 0.00013 21.9 1.4 0.42 10.7 0.0 3.5 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 KFM59301.1 - 0.00025 20.4 0.1 0.025 14.0 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 KFM59301.1 - 0.003 17.3 1.9 0.077 12.8 0.1 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain UPF0122 PF04297.14 KFM59301.1 - 0.0051 17.0 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_Tnp_IS630 PF01710.16 KFM59301.1 - 0.0057 16.7 0.7 0.05 13.7 0.1 2.2 2 0 0 2 2 2 1 Transposase HTH_50 PF18024.1 KFM59301.1 - 0.0058 16.2 0.8 0.027 14.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM59301.1 - 0.02 14.4 0.1 0.24 10.9 0.1 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 MIOX PF05153.15 KFM59302.1 - 6.2e-125 415.8 2.6 8.7e-125 415.3 2.6 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase Swi3 PF07962.12 KFM59302.1 - 0.034 14.1 0.2 0.6 10.1 0.0 2.7 3 0 0 3 3 3 0 Replication Fork Protection Component Swi3 HDOD PF08668.12 KFM59302.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 HDOD domain Dickkopf_N PF04706.12 KFM59303.1 - 0.0041 17.6 2.7 0.0064 17.0 2.7 1.3 1 0 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region Toxin_9 PF02819.15 KFM59303.1 - 0.0065 16.7 6.8 0.0087 16.3 6.8 1.3 1 0 0 1 1 1 1 Spider toxin Toxin_12 PF07740.12 KFM59303.1 - 0.14 12.9 4.2 0.21 12.3 4.2 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin LIM PF00412.22 KFM59305.1 - 8.5e-27 93.2 26.4 2.2e-14 53.4 11.4 2.4 2 0 0 2 2 2 2 LIM domain PDZ_6 PF17820.1 KFM59305.1 - 7e-09 35.4 0.1 1.1e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM59305.1 - 1.1e-08 35.3 0.2 1.7e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFM59305.1 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ_2 PF13180.6 KFM59305.1 - 0.008 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_4 PF17816.1 KFM59305.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Pkinase_Tyr PF07714.17 KFM59306.1 - 2.3e-47 161.5 0.1 5e-47 160.4 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM59306.1 - 7e-40 137.1 0.0 8.5e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFM59306.1 - 7.2e-05 22.2 1.2 0.00012 21.5 1.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM59306.1 - 0.00033 20.6 0.1 0.00092 19.2 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM59306.1 - 0.00087 18.2 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KFM59306.1 - 0.013 15.1 0.1 1.8 8.1 0.1 2.5 2 1 1 3 3 3 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KFM59306.1 - 0.025 13.5 0.9 0.045 12.7 0.1 1.6 1 1 1 2 2 2 0 Haspin like kinase domain B2 PF11473.8 KFM59306.1 - 0.027 14.3 0.1 0.056 13.3 0.1 1.5 1 0 0 1 1 1 0 RNA binding protein B2 RIO1 PF01163.22 KFM59306.1 - 0.038 13.6 0.3 0.056 13.0 0.3 1.2 1 0 0 1 1 1 0 RIO1 family ABC_membrane PF00664.23 KFM59307.1 - 4.3e-108 361.1 15.2 1.6e-56 192.0 0.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFM59307.1 - 1.5e-76 255.5 0.2 3.4e-37 128.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFM59307.1 - 2.3e-12 46.8 1.1 8.9e-06 25.3 0.5 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KFM59307.1 - 2e-08 33.5 0.1 0.00099 18.0 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KFM59307.1 - 2.3e-08 34.6 1.3 0.0016 18.8 1.2 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KFM59307.1 - 1.1e-07 32.2 0.6 0.017 15.4 0.1 3.5 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFM59307.1 - 1.3e-07 31.7 0.0 0.011 15.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KFM59307.1 - 4.3e-07 30.0 0.5 0.0086 15.8 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain Zeta_toxin PF06414.12 KFM59307.1 - 5.2e-07 29.2 0.0 0.031 13.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.14 KFM59307.1 - 6.6e-07 29.4 0.0 0.25 11.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KFM59307.1 - 6.2e-06 25.9 0.2 0.092 12.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF815 PF05673.13 KFM59307.1 - 8e-06 25.2 0.1 0.068 12.3 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_21 PF13304.6 KFM59307.1 - 8.6e-06 25.8 0.1 0.13 12.0 0.0 3.9 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KFM59307.1 - 9.3e-06 26.1 0.0 0.19 12.1 0.0 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFM59307.1 - 2.2e-05 24.2 0.8 0.063 13.0 0.6 2.9 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KFM59307.1 - 2.9e-05 23.9 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KFM59307.1 - 5.9e-05 22.7 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 KFM59307.1 - 0.00013 21.9 0.1 0.6 10.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain PRK PF00485.18 KFM59307.1 - 0.00038 20.2 0.1 0.59 9.8 0.0 2.5 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 KFM59307.1 - 0.0006 19.5 0.4 0.49 10.0 0.0 2.5 3 0 0 3 3 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 KFM59307.1 - 0.00072 19.8 0.1 2.1 8.5 0.0 3.0 2 1 1 3 3 3 2 AAA domain G-alpha PF00503.20 KFM59307.1 - 0.00094 18.4 0.0 0.4 9.8 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit NB-ARC PF00931.22 KFM59307.1 - 0.0011 18.2 0.1 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.6 KFM59307.1 - 0.0016 18.1 0.1 0.9 9.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 KFM59307.1 - 0.0018 18.5 4.8 1.3 9.3 0.6 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KFM59307.1 - 0.0027 17.9 0.0 4.6 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFM59307.1 - 0.0028 18.0 0.0 4.1 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 KFM59307.1 - 0.0028 17.7 0.0 3.5 7.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KFM59307.1 - 0.0054 16.5 0.7 0.64 9.7 0.0 3.0 2 1 1 3 3 2 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KFM59307.1 - 0.0055 16.8 0.2 1.5 9.0 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.12 KFM59307.1 - 0.0056 16.6 0.1 3.8 7.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KFM59307.1 - 0.0067 17.0 0.0 4.1 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFM59307.1 - 0.011 16.3 0.0 9.2 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KFM59307.1 - 0.012 15.5 0.1 7.1 6.5 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase DUF87 PF01935.17 KFM59307.1 - 0.016 15.3 0.1 4.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Septin PF00735.18 KFM59307.1 - 0.057 12.7 0.3 12 5.0 0.0 2.9 3 0 0 3 3 3 0 Septin AAA_19 PF13245.6 KFM59307.1 - 0.059 13.7 0.2 6.5 7.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KFM59307.1 - 0.079 13.0 0.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE tRNA_lig_kinase PF08303.11 KFM59307.1 - 0.092 12.8 0.1 16 5.6 0.0 2.5 2 0 0 2 2 2 0 tRNA ligase kinase domain FtsK_SpoIIIE PF01580.18 KFM59307.1 - 0.098 12.0 0.0 16 4.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 KFM59307.1 - 0.11 12.2 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.7 KFM59307.1 - 0.52 9.2 2.1 2.2 7.1 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain MIB_HERC2 PF06701.13 KFM59313.1 - 2.7e-47 158.8 18.4 1.8e-28 98.6 5.9 3.8 3 0 0 3 3 3 2 Mib_herc2 SH3_15 PF18346.1 KFM59313.1 - 5e-43 145.3 8.5 2.8e-22 78.8 0.0 3.5 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank_2 PF12796.7 KFM59313.1 - 3.8e-33 113.9 1.6 1.9e-14 54.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM59313.1 - 3.8e-27 94.3 5.8 2.6e-12 47.0 0.4 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM59313.1 - 3.7e-26 90.9 6.4 2.8e-11 43.4 0.0 4.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFM59313.1 - 2e-20 72.3 15.1 0.00032 21.0 0.2 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KFM59313.1 - 1.9e-17 61.6 7.8 0.079 13.5 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat ZZ PF00569.17 KFM59313.1 - 6.5e-11 41.9 8.1 1.2e-10 41.0 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF4314 PF14192.6 KFM59313.1 - 0.019 14.8 4.0 2.2 8.2 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4314) zf-C3HC4_3 PF13920.6 KFM59314.1 - 8.2e-32 108.8 43.5 3.1e-11 42.9 11.8 3.6 3 0 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 KFM59314.1 - 8e-16 57.9 0.0 7.4e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM59314.1 - 9.8e-13 47.9 0.0 2.2e-05 24.7 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KFM59314.1 - 2.5e-11 44.0 0.3 2e-08 34.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM59314.1 - 4e-11 43.2 0.3 6.2e-07 29.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-C3HC4_2 PF13923.6 KFM59314.1 - 1.6e-09 37.4 10.5 1.6e-09 37.4 10.5 4.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM59314.1 - 1.8e-09 37.3 42.4 0.0052 16.6 7.9 4.7 3 1 1 4 4 4 3 Prokaryotic RING finger family 4 Ank_3 PF13606.6 KFM59314.1 - 3.8e-08 33.0 3.2 0.00081 19.7 0.0 4.6 5 0 0 5 5 4 1 Ankyrin repeat zf-C3HC4 PF00097.25 KFM59314.1 - 0.01 15.7 9.0 0.01 15.7 9.0 4.4 2 1 1 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM59314.1 - 0.02 14.8 9.6 0.02 14.8 9.6 4.9 4 2 1 5 5 5 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM59314.1 - 0.027 14.5 3.4 0.027 14.5 3.4 4.9 3 1 1 4 4 4 0 RING-type zinc-finger DUF1394 PF07159.12 KFM59316.1 - 2.9e-44 151.5 0.0 3.2e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Focal_AT PF03623.13 KFM59316.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Focal adhesion targeting region TBK1_ULD PF18396.1 KFM59317.1 - 0.00016 21.5 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2309 PF10070.9 KFM59317.1 - 0.029 12.7 0.1 0.034 12.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Cytochrom_C_2 PF01322.20 KFM59319.1 - 0.048 14.5 2.8 0.059 14.3 0.6 2.4 2 1 0 2 2 2 0 Cytochrome C' Vps23_core PF09454.10 KFM59319.1 - 0.068 13.1 0.3 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Vps23 core domain Golgin_A5 PF09787.9 KFM59319.1 - 0.76 9.2 36.0 0.28 10.6 17.5 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KFM59319.1 - 1.2 8.5 17.2 0.1 11.9 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KFM59319.1 - 1.5 7.6 41.1 0.24 10.3 0.4 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KFM59319.1 - 5.4 7.0 18.1 0.43 10.6 4.0 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KFM59319.1 - 6.1 5.2 8.2 47 2.3 0.1 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 KFM59319.1 - 8.4 6.9 9.9 2.6 8.6 0.1 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein ATG11 PF10377.9 KFM59320.1 - 1e-16 61.2 0.7 1e-16 61.2 0.7 2.9 2 2 1 3 3 3 1 Autophagy-related protein 11 OmpH PF03938.14 KFM59320.1 - 0.057 13.8 23.7 0.084 13.2 0.5 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GIDA PF01134.22 KFM59320.1 - 0.35 9.9 9.2 0.23 10.5 5.3 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A TipAS PF07739.13 KFM59320.1 - 0.63 10.6 9.7 8.8 6.9 5.4 2.6 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain PIN_8 PF18476.1 KFM59320.1 - 1.8 8.4 12.7 4.3 7.1 9.6 2.2 2 0 0 2 2 2 0 PIN like domain Lectin_N PF03954.14 KFM59320.1 - 4.1 7.2 13.3 0.29 10.9 1.8 3.0 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DNA_primase_lrg PF04104.14 KFM59320.1 - 8 5.8 16.3 2.7 7.3 9.4 2.2 1 1 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit DUF4744 PF15918.5 KFM59321.1 - 0.067 14.0 2.9 0.17 12.7 0.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4744) GCM PF03615.15 KFM59322.1 - 1.8e-42 144.5 1.5 2.3e-42 144.2 1.5 1.1 1 0 0 1 1 1 1 GCM motif protein HTH_Tnp_Tc3_2 PF01498.18 KFM59323.1 - 4e-16 59.0 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59323.1 - 1.5e-13 50.7 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59323.1 - 3.1e-07 30.0 1.6 7.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59323.1 - 0.003 17.3 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59323.1 - 2.8 8.6 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain PQ-loop PF04193.14 KFM59325.1 - 2e-39 133.2 13.4 4.6e-21 74.3 3.9 2.8 2 0 0 2 2 2 2 PQ loop repeat BSMAP PF12280.8 KFM59327.1 - 3.5e-35 121.9 6.0 3.5e-35 121.9 6.0 2.4 1 1 1 2 2 2 2 Brain specific membrane anchored protein Sde2_N_Ubi PF13019.6 KFM59329.1 - 2.4e-22 79.5 3.3 7.5e-22 77.9 3.3 1.8 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Telomere_Sde2_2 PF13297.6 KFM59329.1 - 9.7e-21 73.2 0.1 9.7e-21 73.2 0.1 2.1 2 0 0 2 2 2 1 Telomere stability C-terminal RA PF00788.23 KFM59330.1 - 1.6e-11 44.6 0.0 2.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain VPS9 PF02204.18 KFM59330.1 - 0.00034 20.8 0.0 0.00067 19.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain FERM_f0 PF16511.5 KFM59330.1 - 0.0062 16.8 0.0 0.0091 16.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM SH2 PF00017.24 KFM59331.1 - 3.5e-10 39.8 0.0 8.9e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain LIN52 PF10044.9 KFM59332.1 - 5.1e-36 123.3 0.0 6.8e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 Retinal tissue protein 5_3_exonuc PF01367.20 KFM59332.1 - 0.11 13.1 0.0 0.3 11.7 0.0 1.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DDE_3 PF13358.6 KFM59333.1 - 2.5e-11 43.6 0.0 3.2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase_Tyr PF07714.17 KFM59334.1 - 1.3e-96 322.8 0.0 1.9e-96 322.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM59334.1 - 8.3e-46 156.5 0.0 1.2e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFM59334.1 - 9e-22 77.0 0.3 1.9e-21 76.0 0.3 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFM59334.1 - 2.6e-15 55.8 0.3 7.1e-15 54.4 0.3 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM59334.1 - 1.9e-10 40.4 0.5 4.6e-10 39.2 0.5 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM59334.1 - 2.6e-06 27.0 0.1 5.7e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 KFM59334.1 - 9.7e-05 22.4 0.0 0.00032 20.7 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 KFM59334.1 - 0.0003 21.0 3.5 0.0019 18.4 1.7 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Kinase-like PF14531.6 KFM59334.1 - 0.0012 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like hSH3 PF14603.6 KFM59334.1 - 0.12 12.9 0.1 0.52 10.8 0.0 2.1 2 0 0 2 2 2 0 Helically-extended SH3 domain FERM_M PF00373.18 KFM59335.1 - 4.5e-41 140.0 0.0 1.1e-40 138.7 0.0 1.7 1 1 0 1 1 1 1 FERM central domain PH PF00169.29 KFM59335.1 - 3e-08 34.1 0.0 4.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 PH domain Cytidylate_kin PF02224.18 KFM59335.1 - 0.2 11.4 0.1 0.32 10.7 0.1 1.2 1 0 0 1 1 1 0 Cytidylate kinase Proteasome PF00227.26 KFM59336.1 - 1.9e-46 158.0 0.4 2.3e-46 157.7 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit SapB_1 PF05184.15 KFM59336.1 - 0.19 11.8 0.1 0.76 9.9 0.0 2.0 2 0 0 2 2 2 0 Saposin-like type B, region 1 FliT PF05400.13 KFM59337.1 - 5.6e-05 23.9 0.1 0.00059 20.6 0.1 2.2 2 0 0 2 2 2 1 Flagellar protein FliT Par3_HAL_N_term PF12053.8 KFM59337.1 - 0.00015 21.9 0.0 0.00051 20.2 0.0 1.8 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Pox_A28 PF04584.14 KFM59337.1 - 0.00068 19.9 1.2 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A28 family LRR_4 PF12799.7 KFM59337.1 - 0.058 13.8 2.9 0.22 12.0 2.9 2.1 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 KFM59338.1 - 2.5e-18 66.4 0.0 8.2e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_12 PF13424.6 KFM59338.1 - 6.1e-18 64.9 6.4 1.7e-07 31.4 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat Ank_5 PF13857.6 KFM59338.1 - 1.5e-17 63.5 0.1 8.7e-10 38.7 0.0 2.9 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM59338.1 - 3.6e-17 60.7 0.1 7.9e-08 32.0 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFM59338.1 - 1.9e-13 50.6 0.0 9.8e-13 48.4 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM59338.1 - 2.2e-12 46.8 0.0 1.1e-05 25.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat TPR_2 PF07719.17 KFM59338.1 - 5.6e-12 44.8 14.5 0.18 12.0 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFM59338.1 - 3.7e-07 29.7 18.8 0.16 11.8 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM59338.1 - 3.9e-07 29.8 20.5 0.92 9.9 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM59338.1 - 3.5e-05 24.0 10.8 0.033 14.4 0.2 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFM59338.1 - 0.00016 22.2 0.4 12 6.6 0.4 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM59338.1 - 0.0019 18.9 0.1 85 4.4 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM59338.1 - 0.002 18.4 0.4 0.051 14.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM59338.1 - 0.0023 17.8 7.8 0.32 11.1 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM59338.1 - 0.04 13.1 1.3 0.3 10.3 0.0 2.7 2 2 1 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 KFM59338.1 - 0.11 12.2 9.0 13 5.4 6.0 3.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) LppC PF04348.13 KFM59338.1 - 0.14 10.9 0.6 0.23 10.2 0.6 1.2 1 0 0 1 1 1 0 LppC putative lipoprotein TPR_10 PF13374.6 KFM59338.1 - 0.26 11.2 5.7 49 4.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM59338.1 - 1.6 9.5 7.6 18 6.2 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat tRNA-synt_1b PF00579.25 KFM59339.1 - 1.3e-65 221.6 0.0 1.7e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.13 KFM59339.1 - 0.075 13.0 0.0 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) HTH_Tnp_Tc3_2 PF01498.18 KFM59341.1 - 2e-16 60.0 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59341.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotran_gag_2 PF14223.6 KFM59342.1 - 1.4e-21 76.6 4.5 2.8e-21 75.7 4.5 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 KFM59342.1 - 2.6e-13 50.2 0.0 6.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KFM59342.1 - 9.7e-07 28.6 2.3 1.1e-06 28.3 0.2 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 KFM59342.1 - 0.0079 15.9 0.0 0.044 13.6 0.0 2.3 1 0 0 1 1 1 1 Integrase core domain LPD11 PF18824.1 KFM59342.1 - 0.029 14.4 0.5 13 5.9 0.0 3.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 DUF507 PF04368.13 KFM59342.1 - 0.12 12.2 0.1 0.12 12.2 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF507) zf-CCHC PF00098.23 KFM59342.1 - 0.8 9.9 5.3 2 8.6 5.3 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KFM59342.1 - 0.85 9.4 5.4 1.7 8.4 5.4 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 KFM59342.1 - 5.2 7.0 14.8 0.064 13.1 7.1 1.9 2 0 0 2 2 2 0 Zinc knuckle EMP24_GP25L PF01105.24 KFM59343.1 - 3.8e-17 62.8 0.0 4.2e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sld5 PF05916.11 KFM59344.1 - 0.0018 18.7 0.0 0.0029 18.1 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Peptidase_M24_C PF16188.5 KFM59344.1 - 0.09 12.8 0.0 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 Kelch_1 PF01344.25 KFM59345.1 - 1.6e-90 296.5 12.0 1.1e-16 60.1 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFM59345.1 - 2.2e-51 170.5 5.0 4e-10 39.6 0.0 6.4 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFM59345.1 - 1.2e-43 145.5 1.5 1.3e-07 31.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 KFM59345.1 - 3.5e-33 113.8 0.7 3.5e-33 113.8 0.7 2.0 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFM59345.1 - 9.3e-30 102.4 0.2 9.2e-05 22.4 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KFM59345.1 - 7.4e-29 100.2 1.1 2.5e-28 98.5 0.2 2.1 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 KFM59345.1 - 1.1e-23 83.0 2.4 0.00046 20.4 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM59345.1 - 3.3e-10 39.7 12.2 0.16 12.0 0.0 6.5 7 1 1 8 8 8 4 Kelch motif DUF3342 PF11822.8 KFM59345.1 - 9.5e-07 28.9 1.1 2.5e-05 24.4 0.1 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3342) PAN_1 PF00024.26 KFM59346.1 - 1.2e-06 28.4 0.2 1.2e-06 28.3 0.2 1.1 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KFM59346.1 - 0.0001 22.1 0.5 0.00015 21.6 0.5 1.3 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KFM59347.1 - 1.5e-10 40.9 0.1 5.6e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 PAN domain p450 PF00067.22 KFM59349.1 - 4.3e-61 207.1 0.0 4.8e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bac_rhamnosid6H PF17389.2 KFM59349.1 - 0.0076 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4082 PF13313.6 KFM59349.1 - 0.19 11.8 0.0 0.41 10.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) p450 PF00067.22 KFM59350.1 - 1.2e-59 202.4 0.0 1.3e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM59351.1 - 1.2e-58 199.0 0.0 1.4e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_Tnp_Tc3_2 PF01498.18 KFM59352.1 - 5e-16 58.7 3.5 6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59352.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59352.1 - 2.1e-07 30.6 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59352.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59352.1 - 0.03 14.4 0.4 0.094 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM59352.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59353.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59353.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59353.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59353.1 - 0.0023 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59353.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_AraC PF00165.23 KFM59354.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF4974 PF16344.5 KFM59355.1 - 0.12 12.4 0.0 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) Hemocyanin_M PF00372.19 KFM59357.1 - 6.8e-73 245.2 0.0 1e-72 244.6 0.0 1.3 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Hemocyanin_C PF03723.14 KFM59357.1 - 1.1e-62 211.6 0.0 1.5e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_N PF03722.14 KFM59357.1 - 2e-19 70.3 0.1 7.3e-18 65.3 0.0 2.6 2 1 1 3 3 3 1 Hemocyanin, all-alpha domain Tyrosinase PF00264.20 KFM59357.1 - 2.2e-07 31.4 0.1 3.3e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase HTH_Tnp_Tc3_2 PF01498.18 KFM59359.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59359.1 - 9e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-MYND PF01753.18 KFM59363.1 - 3.6e-05 23.8 7.6 4.8e-05 23.4 7.6 1.2 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KFM59363.1 - 0.035 14.0 6.3 0.047 13.6 6.3 1.3 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 KFM59363.1 - 0.05 13.9 4.7 0.076 13.3 4.7 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding p450 PF00067.22 KFM59364.1 - 1.2e-14 54.0 0.0 1.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAM178 PF14816.6 KFM59364.1 - 0.047 12.7 0.0 0.54 9.2 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function, FAM178 SchA_CurD PF04486.12 KFM59364.1 - 0.094 12.8 0.1 0.2 11.8 0.0 1.5 2 0 0 2 2 2 0 SchA/CurD like domain RVT_1 PF00078.27 KFM59365.1 - 6.9e-31 107.5 0.0 7.5e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PfkB PF00294.24 KFM59366.1 - 2.1e-07 30.6 0.0 2.1e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Aldo_ket_red PF00248.21 KFM59367.1 - 2.6e-13 49.9 0.0 2.7e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CoA_trans PF01144.23 KFM59368.1 - 3e-49 167.3 4.2 1.2e-40 139.3 0.7 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KFM59368.1 - 4.8e-08 33.1 0.2 7.4e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Nop52 PF05997.12 KFM59369.1 - 1.3e-05 25.1 0.0 1.4e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF3884 PF13024.6 KFM59369.1 - 0.0045 16.5 0.0 0.0049 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3884) Leuk-A4-hydro_C PF09127.11 KFM59369.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal HEAT PF02985.22 KFM59369.1 - 0.16 12.3 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 HEAT repeat NKAP PF15692.5 KFM59370.1 - 3.1e-09 37.4 35.7 1.8e-06 28.5 0.8 3.5 1 1 2 3 3 3 2 NF-kappa-B-activating protein DUF4280 PF14107.6 KFM59370.1 - 0.84 10.5 4.5 1.3 9.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4280) PTS_EIIB PF00367.20 KFM59371.1 - 0.093 12.2 0.4 0.16 11.5 0.4 1.3 1 0 0 1 1 1 0 phosphotransferase system, EIIB ABC_tran PF00005.27 KFM59372.1 - 0.019 15.5 3.0 0.18 12.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 KFM59372.1 - 0.033 14.1 0.1 0.081 12.8 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase bPH_1 PF08000.11 KFM59372.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain MMR_HSR1 PF01926.23 KFM59372.1 - 0.095 12.8 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 KFM59373.1 - 2.6e-121 405.1 2.3 3e-121 404.9 2.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFM59373.1 - 2.9e-16 59.4 0.8 3.4e-12 46.2 0.0 2.8 2 1 1 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM59373.1 - 6.3e-05 22.4 0.5 0.044 13.1 0.2 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFM59373.1 - 0.0021 18.3 0.1 1.9 8.7 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFM59373.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KFM59373.1 - 0.022 15.1 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain HTH_Tnp_Tc3_2 PF01498.18 KFM59374.1 - 2.5e-12 46.9 1.6 4.7e-12 46.0 1.6 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59374.1 - 1e-10 41.5 0.0 2.1e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.6 KFM59374.1 - 0.018 15.1 0.8 0.071 13.2 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain MTS PF05175.14 KFM59376.1 - 0.0029 17.2 0.0 0.0042 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFM59376.1 - 0.0086 15.5 0.0 1.5 8.2 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) AMP-binding PF00501.28 KFM59377.1 - 3.5e-75 253.2 0.0 4.2e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM59377.1 - 1.1e-05 26.3 0.0 2.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UQ_con PF00179.26 KFM59378.1 - 2.9e-53 179.3 0.0 3.3e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM59378.1 - 0.002 17.8 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFM59378.1 - 0.0027 18.0 0.0 0.0047 17.2 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KFM59378.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain HARE-HTH PF05066.13 KFM59378.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Peptidase_C78 PF07910.13 KFM59379.1 - 3.6e-52 176.9 0.1 5.7e-52 176.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 KFM59379.1 - 0.023 14.1 1.5 0.29 10.5 0.2 2.9 1 1 1 3 3 3 0 Peptidase family C54 LRR_8 PF13855.6 KFM59381.1 - 4.5e-99 324.2 96.4 2.6e-13 49.5 4.1 12.8 5 2 9 15 15 15 14 Leucine rich repeat LRR_4 PF12799.7 KFM59381.1 - 1.6e-47 158.6 90.0 8.1e-06 26.1 1.5 15.9 13 3 3 16 16 16 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM59381.1 - 1.6e-32 112.2 1.5 1.9e-08 34.3 0.1 6.7 3 1 2 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM59381.1 - 2.7e-20 72.6 39.6 4.6e-07 29.5 0.4 8.0 3 2 5 8 8 8 8 Leucine-rich repeat TIR PF01582.20 KFM59381.1 - 1.7e-16 60.5 0.0 3.1e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFM59381.1 - 1.3e-14 54.8 0.0 5.3e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 TIR domain LRR_1 PF00560.33 KFM59381.1 - 1.3e-10 40.3 70.7 5.5 7.9 0.9 21.7 21 3 0 21 21 21 4 Leucine Rich Repeat DUF1863 PF08937.11 KFM59381.1 - 2.7e-05 24.5 0.2 7.4e-05 23.1 0.2 1.7 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_6 PF13516.6 KFM59381.1 - 0.00066 19.5 73.4 0.14 12.3 0.5 18.6 21 0 0 21 21 21 3 Leucine Rich repeat Homeodomain PF00046.29 KFM59381.1 - 1.8 8.5 5.1 20 5.1 0.0 4.9 6 0 0 6 6 6 0 Homeodomain HTH_Tnp_Tc3_2 PF01498.18 KFM59382.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59382.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59384.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59384.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59384.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59384.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59384.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59385.1 - 5.1e-16 58.7 3.5 6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59385.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59385.1 - 2.2e-07 30.5 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59385.1 - 0.0026 17.5 0.6 0.0079 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59386.1 - 2.2e-16 59.9 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59386.1 - 1.9e-13 50.4 0.0 3.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease AP_endonuc_2 PF01261.24 KFM59387.1 - 3.1e-12 46.4 0.0 3.7e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PDE8 PF08629.10 KFM59390.1 - 1.3e-08 34.7 0.1 2.6e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 PDE8 phosphodiesterase DUF1759 PF03564.15 KFM59393.1 - 6.3e-17 61.9 0.1 6.9e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) PqqD PF05402.12 KFM59393.1 - 0.035 14.4 0.0 4.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) HTH_Tnp_Tc3_2 PF01498.18 KFM59396.1 - 4.8e-16 58.8 3.5 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59396.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59396.1 - 1.8e-07 30.8 1.2 6.9e-07 28.9 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59396.1 - 0.0026 17.5 0.6 0.0074 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59396.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59397.1 - 8.6e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59397.1 - 2e-15 56.9 0.1 2.1e-14 53.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59397.1 - 0.00078 20.0 1.5 0.00078 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59397.1 - 0.0031 17.2 0.1 0.12 12.2 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59397.1 - 0.018 15.2 0.1 0.069 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM59397.1 - 0.038 14.0 0.4 0.038 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Mo25 PF08569.11 KFM59398.1 - 1.3e-107 359.9 6.5 1.5e-107 359.8 6.5 1.0 1 0 0 1 1 1 1 Mo25-like DDE_3 PF13358.6 KFM59399.1 - 3.5e-12 46.3 0.0 6.3e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59399.1 - 1.2e-08 35.0 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM59399.1 - 0.0004 20.9 1.1 0.0004 20.9 1.1 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_3 PF01381.22 KFM59399.1 - 0.0079 16.2 0.3 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM59399.1 - 0.0093 15.9 0.5 0.033 14.2 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KFM59399.1 - 0.025 14.4 0.1 0.12 12.3 0.0 2.1 1 1 1 2 2 2 0 MarR family PAX PF00292.18 KFM59399.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain HTH_23 PF13384.6 KFM59399.1 - 0.13 12.1 0.5 0.89 9.4 0.1 2.7 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.6 KFM59399.1 - 0.14 12.3 1.4 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Retrotrans_gag PF03732.17 KFM59401.1 - 0.12 12.7 0.3 0.25 11.6 0.3 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein THAP PF05485.12 KFM59403.1 - 3.4e-06 27.9 0.2 3.8e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 THAP domain DNA_pol_B_exo1 PF03104.19 KFM59403.1 - 0.056 12.6 0.0 0.056 12.6 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Aa_trans PF01490.18 KFM59406.1 - 2.1e-71 240.8 21.4 2.4e-71 240.6 21.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM59406.1 - 1e-11 44.5 11.8 1e-11 44.5 11.8 1.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 KFM59406.1 - 0.0011 17.9 0.3 0.0011 17.9 0.3 3.2 2 1 0 3 3 3 2 Spore germination protein OppC_N PF12911.7 KFM59406.1 - 9.1 6.3 17.7 1.4 9.0 0.3 5.4 6 0 0 6 6 6 0 N-terminal TM domain of oligopeptide transport permease C RRN3 PF05327.11 KFM59407.1 - 1.2e-113 380.6 16.1 2.3e-113 379.7 16.1 1.4 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol3_a_NII PF11490.8 KFM59407.1 - 0.24 11.3 6.3 0.47 10.3 0.8 2.5 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Spot_14 PF07084.12 KFM59408.1 - 5.5e-21 75.3 0.0 7e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 PTPLA PF04387.14 KFM59410.1 - 8.6e-49 165.4 11.3 1e-48 165.2 11.3 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Mntp PF02659.15 KFM59410.1 - 0.35 10.6 1.5 0.35 10.6 0.1 1.7 2 0 0 2 2 2 0 Putative manganese efflux pump Med17 PF10156.9 KFM59411.1 - 3.8e-06 25.9 0.0 6.7e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 Subunit 17 of Mediator complex TFIIE_alpha PF02002.17 KFM59413.1 - 1.3e-26 92.5 3.4 2.7e-26 91.4 3.4 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KFM59413.1 - 1.4e-15 57.4 5.8 1.4e-15 57.4 5.8 2.1 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KFM59413.1 - 7.1e-07 28.6 1.4 1.9e-06 27.3 1.4 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding zf-H2C2_2 PF13465.6 KFM59413.1 - 0.054 14.0 1.1 1.7 9.2 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Macoilin PF09726.9 KFM59413.1 - 0.062 11.9 5.6 0.1 11.1 5.6 1.3 1 0 0 1 1 1 0 Macoilin family Acyltransferase PF01553.21 KFM59414.1 - 0.038 13.6 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase Asp_protease PF09668.10 KFM59415.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM59415.1 - 0.039 14.5 0.0 0.07 13.7 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KFM59415.1 - 0.045 13.5 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2833 PF11090.8 KFM59415.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) Retrotran_gag_2 PF14223.6 KFM59416.1 - 1.2e-19 70.3 0.5 1.5e-19 70.1 0.5 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TraY PF05509.11 KFM59416.1 - 0.003 17.6 0.4 0.0049 16.9 0.4 1.3 1 0 0 1 1 1 1 TraY domain SLATT_4 PF18186.1 KFM59416.1 - 0.0064 16.1 0.3 0.0079 15.9 0.3 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 4 DnaJ_C PF01556.18 KFM59418.1 - 1.3e-37 129.1 0.1 1.7e-37 128.8 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFM59418.1 - 8.9e-28 96.2 0.8 8.9e-28 96.2 0.8 1.7 2 0 0 2 2 2 1 DnaJ domain HEPN_LA2681 PF18733.1 KFM59418.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 LA2681-like HEPN AAA_11 PF13086.6 KFM59424.1 - 0.00091 19.1 6.2 0.22 11.3 4.7 2.2 1 1 1 2 2 2 2 AAA domain Phage_HK97_TLTM PF06120.11 KFM59424.1 - 0.011 14.9 0.3 0.018 14.2 0.3 1.2 1 0 0 1 1 1 0 Tail length tape measure protein RVT_1 PF00078.27 KFM59425.1 - 2.7e-45 154.6 0.2 3.7e-45 154.2 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NUC153 PF08159.12 KFM59426.1 - 1.7e-07 30.9 2.0 5.2e-07 29.4 2.0 1.9 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KFM59426.1 - 0.0013 19.5 0.0 4.1 8.5 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3295 PF11702.8 KFM59426.1 - 0.033 13.6 15.8 0.051 12.9 15.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) BUD22 PF09073.10 KFM59426.1 - 0.083 12.2 24.5 0.14 11.5 24.5 1.2 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 KFM59426.1 - 0.097 12.4 9.0 0.18 11.5 9.0 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Peptidase_M16 PF00675.20 KFM59426.1 - 0.53 10.3 5.1 0.51 10.3 0.6 2.5 1 1 0 2 2 2 0 Insulinase (Peptidase family M16) CENP-B_dimeris PF09026.10 KFM59426.1 - 2.7 8.4 13.5 7.9 6.9 13.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KFM59426.1 - 8.3 5.6 13.9 15 4.8 13.9 1.3 1 0 0 1 1 1 0 NOA36 protein ORC2 PF04084.14 KFM59427.1 - 1.4e-90 303.6 5.1 1.7e-90 303.3 5.1 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 UNC-93 PF05978.16 KFM59428.1 - 2e-06 27.6 11.9 3.9e-06 26.7 11.9 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFM59428.1 - 0.00061 18.8 6.4 0.00078 18.5 6.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Virul_fac_BrkB PF03631.15 KFM59428.1 - 0.45 10.1 10.4 1.7 8.2 4.2 2.1 1 1 0 2 2 2 0 Virulence factor BrkB BTB PF00651.31 KFM59429.1 - 3.6e-38 130.2 0.0 1.1e-24 86.8 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM59429.1 - 0.0033 17.5 0.0 0.77 9.9 0.0 2.6 2 0 0 2 2 2 2 BTB And C-terminal Kelch MFS_1 PF07690.16 KFM59430.1 - 1.6e-09 37.2 29.0 1e-05 24.6 11.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.16 KFM59430.1 - 1.7e-08 34.3 8.9 6.6e-08 32.4 8.9 2.1 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 UNC-93 PF05978.16 KFM59431.1 - 1.2e-09 38.1 3.6 2.1e-09 37.3 3.6 1.4 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KFM59431.1 - 0.0018 17.2 0.7 0.0037 16.2 0.7 1.5 1 0 0 1 1 1 1 MFS_1 like family UNC-93 PF05978.16 KFM59432.1 - 5e-12 45.8 5.6 1.4e-11 44.4 5.6 1.8 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFM59432.1 - 4e-05 22.7 2.7 5.5e-05 22.2 2.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFM59432.1 - 0.0033 16.4 1.2 0.0046 15.9 1.2 1.2 1 0 0 1 1 1 1 MFS_1 like family RE_R_Pab1 PF09522.10 KFM59432.1 - 0.049 13.7 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59433.1 - 8.2e-16 58.0 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59433.1 - 7.8e-14 51.7 0.1 9.1e-13 48.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59433.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59433.1 - 0.0022 17.7 0.0 0.1 12.5 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59433.1 - 0.016 15.3 0.1 0.067 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM59433.1 - 0.024 14.7 2.1 0.032 14.2 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM59433.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc5 PF03221.16 KFM59434.1 - 4.4e-12 45.8 0.4 8.3e-12 45.0 0.4 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KFM59434.1 - 2.9e-07 30.3 0.0 5.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM59434.1 - 0.0057 16.4 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 KFM59434.1 - 0.074 13.4 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 Transposase DUF3372 PF11852.8 KFM59434.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Peptidase_S66 PF02016.15 KFM59434.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain HRM PF02793.22 KFM59435.1 - 0.0053 17.0 0.1 0.0094 16.2 0.1 1.4 1 0 0 1 1 1 1 Hormone receptor domain Ig_2 PF13895.6 KFM59435.1 - 0.0086 16.4 0.2 0.061 13.7 0.0 2.1 1 1 1 2 2 2 1 Immunoglobulin domain LisH_2 PF16045.5 KFM59436.1 - 0.0098 14.9 0.2 0.019 14.0 0.2 1.5 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 KFM59436.1 - 0.05 13.9 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 FOP N terminal dimerisation domain HTH_Tnp_Tc3_2 PF01498.18 KFM59437.1 - 3.2e-35 120.2 10.5 1.9e-18 66.4 1.4 2.7 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM59437.1 - 1.5e-13 50.7 0.0 3.8e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59437.1 - 3.7e-07 29.8 1.6 9.7e-07 28.5 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59437.1 - 0.011 15.6 0.5 0.011 15.6 0.5 2.7 3 0 0 3 3 3 0 Homeodomain-like domain HTH_32 PF13565.6 KFM59437.1 - 5.1 7.8 26.6 0.18 12.4 2.0 4.0 3 1 1 4 4 4 0 Homeodomain-like domain EGF_2 PF07974.13 KFM59438.1 - 0.051 13.9 9.7 0.12 12.8 9.7 1.6 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 KFM59438.1 - 1.2 9.5 12.9 0.081 13.2 7.5 1.9 2 1 0 2 2 2 0 EGF-like domain Tma16 PF11176.8 KFM59441.1 - 7.1e-31 107.0 7.1 8.2e-31 106.8 7.1 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF3480 PF11979.8 KFM59441.1 - 0.091 11.7 0.5 0.11 11.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) AD PF09793.9 KFM59441.1 - 1.5 9.0 8.4 0.44 10.7 1.5 2.8 1 1 1 2 2 2 0 Anticodon-binding domain Ceramidase_alk PF04734.13 KFM59442.1 - 1.8e-71 241.3 0.2 2.2e-71 241.0 0.2 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KFM59442.1 - 1e-56 191.4 0.0 1.6e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Peptidase_C21 PF05381.12 KFM59442.1 - 0.034 14.5 0.1 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 Tymovirus endopeptidase BORA_N PF15280.6 KFM59444.1 - 5.1e-16 59.0 5.1 3.4e-14 53.1 5.1 2.0 1 1 0 1 1 1 1 Protein aurora borealis N-terminus E1_4HB PF16191.5 KFM59444.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Spc24 PF08286.11 KFM59446.1 - 0.002 18.3 0.6 0.0024 18.1 0.6 1.3 1 1 0 1 1 1 1 Spc24 subunit of Ndc80 HTH_Tnp_Tc3_2 PF01498.18 KFM59447.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59447.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59448.1 - 2.4e-16 59.7 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59448.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM59449.1 - 1.9e-16 60.2 0.1 5.5e-15 55.4 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59449.1 - 7.7e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM59449.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59449.1 - 0.0023 17.7 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59449.1 - 0.014 15.5 0.1 0.063 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM59449.1 - 0.034 14.2 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Neur_chan_memb PF02932.16 KFM59450.1 - 2.6e-08 34.2 0.0 2.8e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DDE_3 PF13358.6 KFM59451.1 - 2.2e-16 59.9 0.1 8.7e-15 54.8 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59451.1 - 1.1e-15 57.6 6.5 1.8e-15 56.9 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM59451.1 - 0.00089 19.8 1.5 0.00089 19.8 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59451.1 - 0.0059 16.4 0.4 0.14 12.0 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59451.1 - 0.023 14.8 0.1 0.078 13.1 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM59451.1 - 0.043 13.9 0.4 0.043 13.9 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix DUF4371 PF14291.6 KFM59452.1 - 3.8e-26 92.2 0.0 6.7e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DDE_3 PF13358.6 KFM59452.1 - 1.3e-15 57.4 0.1 5e-14 52.3 0.0 2.9 2 1 1 3 3 3 1 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.14 KFM59452.1 - 1.4e-10 40.8 0.1 4.3e-10 39.2 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HTH_Tnp_Tc3_2 PF01498.18 KFM59452.1 - 8.6e-10 38.7 1.0 1.9e-09 37.6 1.0 1.7 1 0 0 1 1 1 1 Transposase DUF659 PF04937.15 KFM59452.1 - 0.0073 16.2 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RSS_P20 PF11757.8 KFM59452.1 - 0.24 11.9 0.1 0.24 11.9 0.1 2.9 3 0 0 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain Neur_chan_LBD PF02931.23 KFM59453.1 - 8.2e-13 48.3 1.1 1.3e-12 47.7 1.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM59454.1 - 4e-35 119.9 10.8 6e-18 64.9 1.5 2.5 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM59454.1 - 4.5e-12 45.9 0.0 1.9e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59454.1 - 4.7e-07 30.3 19.1 0.0009 19.8 1.9 3.5 3 0 0 3 3 3 3 Homeodomain-like domain HTH_12 PF08461.10 KFM59454.1 - 0.029 14.3 2.2 4.9 7.2 0.3 3.0 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain HTH_21 PF13276.6 KFM59454.1 - 0.038 14.1 3.2 4.8 7.4 0.0 3.0 2 0 0 2 2 2 0 HTH-like domain HTH_23 PF13384.6 KFM59454.1 - 0.37 10.6 5.6 7.5 6.5 0.2 3.9 4 0 0 4 4 4 0 Homeodomain-like domain DDE_3 PF13358.6 KFM59455.1 - 5.3e-09 36.0 0.0 8.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59456.1 - 1.7e-13 50.6 3.3 1.7e-13 50.6 1.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59456.1 - 8.1e-13 48.4 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 KFM59456.1 - 1.9e-06 27.9 3.1 0.00068 19.7 0.1 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.6 KFM59456.1 - 0.0009 19.8 7.2 0.0009 19.8 7.2 3.0 3 1 0 3 3 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59456.1 - 0.0012 18.5 7.8 0.14 12.0 0.1 3.1 3 1 0 3 3 3 2 Homeodomain-like domain PAX PF00292.18 KFM59456.1 - 0.0017 18.3 0.1 0.0032 17.4 0.1 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_38 PF13936.6 KFM59456.1 - 0.0024 17.6 3.7 0.071 12.9 0.1 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM59456.1 - 0.0072 15.7 0.8 2.3 7.7 0.1 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 TrmB PF01978.19 KFM59456.1 - 0.0072 16.2 0.2 1.6 8.6 0.1 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 KFM59456.1 - 0.014 15.3 4.2 0.059 13.3 0.1 2.9 3 0 0 3 3 3 0 MarR family HTH_3 PF01381.22 KFM59456.1 - 0.014 15.4 0.7 0.55 10.3 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix HTH_7 PF02796.15 KFM59456.1 - 0.016 15.3 1.3 0.063 13.4 0.5 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM59456.1 - 0.018 15.1 1.7 0.44 10.6 0.3 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_22 PF13309.6 KFM59456.1 - 0.021 14.9 0.1 0.048 13.7 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_37 PF13744.6 KFM59456.1 - 0.045 13.7 0.1 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain DUF5447 PF17525.2 KFM59456.1 - 0.079 13.4 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5447) HTH_24 PF13412.6 KFM59456.1 - 0.26 10.9 0.9 22 4.7 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KFM59456.1 - 0.32 11.0 1.8 2.2 8.3 0.2 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain An_peroxidase PF03098.15 KFM59457.1 - 6.4e-154 513.4 0.0 7.2e-154 513.3 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase TruB_N PF01509.18 KFM59458.1 - 5.1e-19 69.1 0.0 8.7e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFM59458.1 - 0.0029 17.7 0.1 0.0075 16.4 0.1 1.8 1 1 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Cas_Cas4 PF01930.17 KFM59459.1 - 1.1 9.3 6.8 0.93 9.6 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function DUF83 Ima1_N PF09779.9 KFM59459.1 - 3.9 8.3 16.0 3.5 8.5 11.3 3.0 1 1 1 2 2 2 0 Ima1 N-terminal domain Galactosyl_T PF01762.21 KFM59461.1 - 1.4e-50 171.8 0.0 2.1e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFM59461.1 - 0.071 12.5 1.0 0.13 11.7 1.0 1.5 1 1 0 1 1 1 0 Fringe-like MIP-T3 PF10243.9 KFM59462.1 - 2.4e-43 146.7 1.3 2.4e-43 146.7 1.3 2.5 2 1 0 3 3 3 1 Microtubule-binding protein MIP-T3 CH-like domain DDHD PF02862.17 KFM59462.1 - 0.66 10.1 8.4 1.2 9.3 8.4 1.4 1 0 0 1 1 1 0 DDHD domain ALMT PF11744.8 KFM59462.1 - 1.3 7.8 11.9 1.5 7.5 11.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 KFM59462.1 - 1.4 7.0 8.9 1.5 6.9 8.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CTNNB1_binding PF08347.11 KFM59462.1 - 1.7 8.8 9.8 2.7 8.1 9.8 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding SLC12 PF03522.15 KFM59462.1 - 1.8 7.5 14.5 2.5 7.0 14.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 KFM59462.1 - 5.3 6.8 19.0 8 6.2 19.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVT_1 PF00078.27 KFM59463.1 - 2.7e-48 164.4 0.1 3.5e-48 164.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_LYR PF05347.15 KFM59464.1 - 4.3e-11 42.7 0.1 7.7e-11 41.9 0.1 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFM59464.1 - 0.0028 18.4 0.1 0.004 17.9 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF5314 PF17241.2 KFM59465.1 - 0.11 12.2 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5314) SGT1 PF07093.11 KFM59466.1 - 1.6e-95 320.8 8.8 1.8e-95 320.6 8.8 1.0 1 0 0 1 1 1 1 SGT1 protein DUF2740 PF10872.8 KFM59466.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) SGT1 PF07093.11 KFM59467.1 - 8.5e-38 130.2 0.5 9.4e-38 130.0 0.5 1.0 1 0 0 1 1 1 1 SGT1 protein Retrotran_gag_2 PF14223.6 KFM59467.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NPR3 PF03666.13 KFM59468.1 - 3.7e-46 157.9 10.4 1.4e-38 132.9 7.9 2.3 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KFM59468.1 - 8.1e-06 24.8 0.3 0.00095 18.0 0.0 2.1 2 0 0 2 2 2 2 Nitrogen permease regulator 2 PRE_C2HC PF07530.11 KFM59469.1 - 3.3e-06 27.1 0.1 4.7e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Associated with zinc fingers NCD3G PF07562.14 KFM59469.1 - 0.018 15.0 0.7 0.031 14.3 0.7 1.3 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR zf-H2C2_2 PF13465.6 KFM59470.1 - 1e-10 41.5 26.9 1.3e-06 28.6 4.8 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM59470.1 - 5e-09 35.7 18.0 0.0002 21.1 3.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM59470.1 - 0.001 19.4 28.0 0.0026 18.1 2.8 3.8 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-Sec23_Sec24 PF04810.15 KFM59470.1 - 0.0035 17.4 5.9 0.88 9.7 0.3 4.3 4 0 0 4 4 4 1 Sec23/Sec24 zinc finger A2L_zn_ribbon PF08792.10 KFM59470.1 - 0.05 13.3 5.1 0.8 9.5 0.1 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-MYST PF17772.1 KFM59470.1 - 0.15 11.7 9.1 1.1 8.9 0.6 2.5 2 0 0 2 2 2 0 MYST family zinc finger domain C1_1 PF00130.22 KFM59470.1 - 0.19 11.7 6.4 0.45 10.5 0.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFM59470.1 - 0.19 12.5 6.9 3 8.7 5.0 2.2 1 1 1 2 2 2 0 zinc-ribbon family Rubredoxin_2 PF18073.1 KFM59470.1 - 0.23 11.2 9.7 1.2 9.0 0.6 3.2 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-C2H2_4 PF13894.6 KFM59470.1 - 0.33 11.9 25.2 0.38 11.7 1.2 4.0 4 1 0 4 4 4 0 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.11 KFM59470.1 - 0.59 10.1 9.2 9.6 6.2 1.1 3.2 1 1 2 3 3 3 0 Putative transposase DNA-binding domain zf-C2H2_jaz PF12171.8 KFM59470.1 - 0.75 10.1 15.2 0.49 10.8 0.9 3.6 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-FPG_IleRS PF06827.14 KFM59470.1 - 1.7 8.6 9.7 4.3 7.3 0.4 3.6 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS FYVE_2 PF02318.16 KFM59470.1 - 1.9 8.7 9.7 1.9 8.8 3.5 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger DUF1390 PF07150.11 KFM59470.1 - 4.3 7.0 11.7 1.6 8.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) zf-H2C2_2 PF13465.6 KFM59471.1 - 7.6e-16 57.7 16.6 2.1e-08 34.2 2.7 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59471.1 - 2e-11 43.6 19.1 1e-06 28.8 0.9 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59471.1 - 8.3e-11 41.8 16.4 3.2e-05 24.4 0.7 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM59471.1 - 5.3e-07 29.3 5.1 5.3e-07 29.3 5.1 3.4 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM59471.1 - 1.1e-06 28.8 3.3 1.1e-06 28.8 3.3 2.1 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFM59471.1 - 1.4e-06 28.1 13.2 0.00022 21.1 0.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFM59471.1 - 0.00015 22.1 0.6 0.00015 22.1 0.6 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM59471.1 - 0.00034 20.8 10.9 0.0012 19.1 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM59471.1 - 0.00071 19.3 2.3 0.066 13.0 0.4 2.2 1 1 1 2 2 2 1 GAGA factor zf-C2H2_2 PF12756.7 KFM59471.1 - 0.0026 18.1 9.5 0.36 11.2 0.6 3.1 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFM59471.1 - 0.0064 16.6 2.0 0.22 11.6 0.7 2.5 2 1 0 2 2 2 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KFM59471.1 - 0.011 15.7 6.1 0.095 12.7 3.5 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_9 PF16293.5 KFM59471.1 - 0.034 14.0 3.0 1.6 8.6 0.1 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-TFIIIC PF12660.7 KFM59471.1 - 0.06 13.3 3.8 0.33 10.9 1.8 2.3 2 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex C1_1 PF00130.22 KFM59471.1 - 0.06 13.2 8.1 2 8.4 0.2 2.9 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_10 PF10058.9 KFM59471.1 - 0.15 11.8 3.9 7.8 6.3 0.1 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 KFM59471.1 - 0.16 12.0 7.5 4.3 7.4 7.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 KFM59471.1 - 0.18 11.4 9.0 2 8.0 0.3 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger A2L_zn_ribbon PF08792.10 KFM59471.1 - 0.3 10.8 4.5 20 5.1 0.2 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-AN1 PF01428.16 KFM59471.1 - 0.38 11.0 7.1 9.3 6.5 0.2 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger HypA PF01155.19 KFM59471.1 - 0.4 10.7 3.6 0.71 9.9 0.9 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 KFM59471.1 - 0.48 10.7 6.2 1.2 9.4 2.4 2.3 2 1 0 2 2 2 0 TFIIH C1-like domain zf-C2HE PF16278.5 KFM59471.1 - 0.72 10.4 12.7 7.8 7.0 5.1 3.1 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3 PF13878.6 KFM59471.1 - 0.72 9.7 0.0 0.72 9.7 0.0 3.0 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO OrfB_Zn_ribbon PF07282.11 KFM59471.1 - 0.79 9.7 6.5 9.6 6.2 3.1 2.8 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn_ribbon_SprT PF17283.2 KFM59471.1 - 1.2 9.1 15.2 0.21 11.5 3.7 3.0 1 1 2 3 3 3 0 SprT-like zinc ribbon domain zf_C2H2_ZHX PF18387.1 KFM59471.1 - 1.7 8.3 13.2 0.63 9.7 0.3 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_4 PF13717.6 KFM59471.1 - 6.8 6.7 8.8 8.8 6.3 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain TFIIS_C PF01096.18 KFM59471.1 - 7.6 6.5 9.6 12 5.8 0.4 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-H2C2_2 PF13465.6 KFM59472.1 - 2.5e-09 37.1 20.2 4.2e-08 33.2 2.8 4.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59472.1 - 1.5e-05 25.2 29.4 0.008 16.6 1.0 3.9 4 1 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM59472.1 - 1.6e-05 25.1 4.0 0.0015 18.7 0.3 4.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFM59472.1 - 1.6e-05 25.4 19.5 0.079 13.8 2.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM59472.1 - 0.0022 18.3 19.2 0.028 14.8 1.1 3.9 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFM59472.1 - 0.0035 17.6 11.1 1.1 9.6 0.5 3.1 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM59472.1 - 0.0082 15.9 2.6 0.0082 15.9 2.6 3.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KFM59472.1 - 0.027 14.9 9.8 3 8.4 1.4 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 KFM59472.1 - 0.22 11.2 0.2 0.22 11.2 0.2 2.6 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain BolA PF01722.18 KFM59472.1 - 0.23 11.8 1.7 1.3 9.3 0.2 2.2 1 1 1 2 2 2 0 BolA-like protein GAGA PF09237.11 KFM59472.1 - 0.77 9.6 4.9 3.6 7.5 0.4 2.8 1 1 2 3 3 3 0 GAGA factor Spidroin_N PF16763.5 KFM59473.1 - 1.6e-33 115.4 6.5 3e-33 114.5 6.5 1.4 1 0 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term Coiled PF05710.12 KFM59473.1 - 0.0069 17.2 0.7 0.0069 17.2 0.7 2.8 1 1 1 2 2 2 1 Coiled coil B56 PF01603.20 KFM59475.1 - 2.4e-182 606.6 5.0 2.9e-182 606.3 5.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFM59475.1 - 0.05 13.5 4.1 1.1 9.1 0.2 3.0 2 2 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UAE_UbL PF14732.6 KFM59475.1 - 0.1 13.2 1.8 2.8 8.6 1.0 2.9 3 0 0 3 3 3 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DDE_3 PF13358.6 KFM59479.1 - 3.3e-05 23.7 0.1 4.2e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank_2 PF12796.7 KFM59482.1 - 5.2e-105 344.2 17.5 6.9e-15 55.4 0.0 10.7 2 1 9 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM59482.1 - 9.8e-94 306.6 16.2 8.8e-11 42.1 0.0 14.4 4 3 10 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 KFM59482.1 - 3.6e-80 261.2 34.0 3.5e-08 33.5 0.1 18.6 19 0 0 19 19 19 14 Ankyrin repeat Ank_5 PF13857.6 KFM59482.1 - 2.2e-68 225.4 34.2 1.3e-13 50.8 0.7 13.7 3 3 9 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM59482.1 - 6.4e-61 195.1 10.3 0.00068 19.9 0.0 17.2 18 0 0 18 18 18 12 Ankyrin repeat AAA_16 PF13191.6 KFM59482.1 - 2e-06 28.3 0.0 8.2e-06 26.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFM59482.1 - 0.00041 20.3 0.0 0.0013 18.6 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KFM59482.1 - 0.057 13.7 0.1 0.73 10.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF674 PF05056.12 KFM59482.1 - 0.071 12.0 0.5 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF674) Retrotran_gag_2 PF14223.6 KFM59483.1 - 4.2e-26 91.3 0.1 7e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KFM59483.1 - 1.9e-07 30.6 0.5 4.2e-07 29.5 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.23 KFM59483.1 - 0.0023 17.9 2.4 0.0023 17.9 2.4 1.8 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 KFM59483.1 - 0.016 15.4 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 KFM59483.1 - 0.18 11.6 0.6 0.34 10.7 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Prenyltrans PF00432.21 KFM59484.1 - 4.4e-38 128.7 3.0 7.9e-14 51.1 0.2 3.1 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat Prenyltrans PF00432.21 KFM59485.1 - 8.2e-19 67.0 2.7 1.3e-10 40.9 0.0 3.3 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFM59485.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.5 1 1 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Sugar_tr PF00083.24 KFM59486.1 - 2.5e-05 23.4 1.1 2.9e-05 23.1 1.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM59486.1 - 0.00065 18.7 0.0 0.00065 18.7 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Wzy_C PF04932.15 KFM59486.1 - 0.071 12.7 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase MFS_1 PF07690.16 KFM59487.1 - 6.7e-08 31.8 2.0 6.7e-08 31.8 2.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM59487.1 - 2.2e-07 30.1 0.1 3e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KFM59487.1 - 0.00011 20.8 2.2 0.00011 20.8 2.2 1.4 2 0 0 2 2 2 1 MFS/sugar transport protein BT1 PF03092.16 KFM59487.1 - 0.0022 16.3 0.9 0.003 15.9 0.9 1.1 1 0 0 1 1 1 1 BT1 family Sulfotransfer_1 PF00685.27 KFM59489.1 - 2.3e-37 128.9 0.3 8e-37 127.2 0.3 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM59489.1 - 7.1e-06 26.6 0.2 2.5e-05 24.8 0.1 1.8 1 1 1 2 2 2 1 Sulfotransferase family DUF4479 PF14794.6 KFM59489.1 - 0.024 14.5 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) Insulin PF00049.18 KFM59491.1 - 1.9e-13 51.2 4.3 4.6e-13 50.0 4.3 1.6 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFM59491.1 - 0.00016 21.6 0.8 0.24 11.5 0.7 2.1 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type LRR_8 PF13855.6 KFM59492.1 - 2.5e-19 68.8 18.8 4.2e-11 42.4 1.9 4.6 3 2 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KFM59492.1 - 2.2e-09 37.4 21.6 5.9e-05 23.4 0.6 5.8 4 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM59492.1 - 3.9e-07 30.1 2.6 0.023 14.7 0.5 3.2 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM59492.1 - 5.5e-06 26.0 1.1 0.00022 20.8 0.2 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFM59492.1 - 0.00016 21.8 15.4 31 5.6 0.0 8.4 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 KFM59492.1 - 0.33 11.1 12.2 51 4.3 0.0 6.8 8 0 0 8 8 8 0 Leucine Rich repeat DDE_Tnp_1_7 PF13843.6 KFM59493.1 - 1.3e-76 258.2 0.0 1.3e-76 258.2 0.0 1.4 2 0 0 2 2 2 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM59493.1 - 0.015 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 KFM59493.1 - 0.029 14.4 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Zot PF05707.12 KFM59493.1 - 0.057 13.1 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Kinetochor_Ybp2 PF08568.10 KFM59494.1 - 1.7e-25 89.6 19.5 2e-23 82.8 19.5 2.3 1 1 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin CDK2AP PF09806.9 KFM59496.1 - 1.3e-24 87.5 0.4 2.1e-24 86.9 0.4 1.3 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein ANAPC4_WD40 PF12894.7 KFM59497.1 - 0.082 13.2 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Orthopox_F6 PF06601.12 KFM59498.1 - 0.13 12.4 0.7 0.21 11.8 0.4 1.5 1 1 1 2 2 2 0 Orthopoxvirus F6 protein zf-H2C2_2 PF13465.6 KFM59499.1 - 1.5e-34 116.9 38.9 1.6e-08 34.6 2.3 7.1 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59499.1 - 4e-29 99.4 37.7 1.6e-05 25.1 1.5 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59499.1 - 4.7e-23 79.9 35.6 4.6e-05 23.9 1.0 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFM59499.1 - 3.5e-16 59.0 37.3 0.00098 19.4 0.3 6.3 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM59499.1 - 8e-10 38.8 34.2 0.0043 17.3 0.8 7.0 4 2 2 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM59499.1 - 1.4e-08 34.5 50.4 0.00015 21.7 0.8 7.9 6 4 0 6 6 6 3 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM59499.1 - 2.1e-06 27.6 16.7 0.0025 17.8 0.1 5.4 2 2 2 5 5 5 1 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM59499.1 - 3.1e-05 23.8 14.1 0.097 12.6 0.2 5.2 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFM59499.1 - 5.1e-05 22.9 29.9 0.12 12.2 0.3 6.1 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM59499.1 - 0.00058 20.1 30.5 0.023 15.0 7.2 4.2 1 1 3 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 KFM59499.1 - 0.0015 18.4 11.3 0.035 14.1 0.4 4.0 3 1 1 4 4 4 1 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM59499.1 - 0.0024 18.2 32.9 0.21 12.0 1.6 5.7 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM59499.1 - 0.0035 16.9 19.6 1.3 8.6 0.2 6.0 6 0 0 6 6 6 1 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 KFM59499.1 - 0.0091 16.1 11.9 4 7.6 0.1 5.4 6 0 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-FCS PF06467.14 KFM59499.1 - 0.015 15.2 9.5 3.1 7.8 0.0 4.7 3 2 2 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_15 PF17032.5 KFM59499.1 - 0.016 15.9 13.8 0.13 13.1 1.9 3.1 2 1 1 3 3 3 0 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM59499.1 - 0.12 12.3 19.5 14 5.6 0.1 5.6 2 2 4 6 6 6 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM59499.1 - 0.15 12.2 23.7 24 5.2 9.1 4.3 1 1 1 2 2 2 0 FYVE zinc finger DZR PF12773.7 KFM59499.1 - 0.17 11.9 12.0 1.2 9.2 2.5 3.1 1 1 1 2 2 2 0 Double zinc ribbon IGPD PF00475.18 KFM59499.1 - 0.21 11.9 3.9 1.3 9.4 0.6 2.6 2 1 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase DUF5330 PF17264.2 KFM59499.1 - 0.21 11.6 1.3 32 4.6 0.0 3.6 4 0 0 4 4 3 0 Family of unknown function (DUF5330) DUF3268 PF11672.8 KFM59499.1 - 0.23 11.8 5.5 1.2 9.4 0.5 2.6 1 1 0 2 2 2 0 zinc-finger-containing domain zinc_ribbon_4 PF13717.6 KFM59499.1 - 0.42 10.6 11.5 14 5.7 0.1 5.0 5 0 0 5 5 5 0 zinc-ribbon domain zf-HIT PF04438.16 KFM59499.1 - 0.74 9.7 18.2 7.4 6.5 0.2 5.1 5 0 0 5 5 5 0 HIT zinc finger zf-UBP PF02148.19 KFM59499.1 - 0.97 9.8 30.4 4 7.8 4.5 4.2 1 1 2 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein zf-CHCC PF10276.9 KFM59499.1 - 1.4 9.0 10.2 4.2 7.5 1.5 4.3 4 1 0 4 4 4 0 Zinc-finger domain zf-C2H2_8 PF15909.5 KFM59499.1 - 2.8 8.3 18.6 1.1 9.7 1.8 3.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KFM59499.1 - 3.3 7.9 15.0 11 6.2 2.2 4.0 1 1 3 4 4 4 0 Zinc ribbon domain TRAF6_Z2 PF18048.1 KFM59499.1 - 4.1 7.6 23.1 4.6 7.4 0.1 5.9 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 GATA PF00320.27 KFM59499.1 - 4.7 6.9 10.8 10 5.8 0.2 4.4 5 0 0 5 5 5 0 GATA zinc finger zf-H2C2_2 PF13465.6 KFM59500.1 - 2.4e-15 56.1 12.1 2.1e-10 40.5 0.8 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59500.1 - 1.3e-10 41.1 19.4 5.7e-07 29.6 1.3 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59500.1 - 9.6e-08 32.2 17.3 2.9e-05 24.5 1.0 2.7 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM59500.1 - 1.1e-07 31.6 7.6 0.00011 22.1 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM59500.1 - 1.7e-07 31.4 14.4 0.00012 22.4 1.8 2.5 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFM59500.1 - 0.00027 21.3 11.7 0.0065 16.9 1.0 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KFM59500.1 - 0.00027 21.1 9.8 0.0035 17.6 0.6 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Baculo_IE-1 PF05290.11 KFM59500.1 - 0.00074 19.5 1.1 0.12 12.4 0.1 2.0 1 1 1 2 2 2 1 Baculovirus immediate-early protein (IE-0) GAGA PF09237.11 KFM59500.1 - 0.0022 17.7 5.4 0.033 14.0 0.3 2.1 1 1 1 2 2 2 1 GAGA factor zf-C2H2_2 PF12756.7 KFM59500.1 - 0.0043 17.4 6.8 0.097 13.0 0.8 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFM59500.1 - 0.0043 17.1 1.3 1 9.5 0.2 2.1 2 0 0 2 2 2 1 Zinc ribbon domain zf_UBZ PF18439.1 KFM59500.1 - 0.0054 16.3 1.9 0.64 9.7 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 KFM59500.1 - 0.0054 16.4 0.3 0.0054 16.4 0.3 3.6 3 1 0 3 3 3 1 C2H2-type zinc-finger domain C1_1 PF00130.22 KFM59500.1 - 0.006 16.5 3.6 0.021 14.7 3.5 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2197 PF09963.9 KFM59500.1 - 0.0067 16.7 4.0 0.79 10.0 0.4 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) HypA PF01155.19 KFM59500.1 - 0.0087 16.1 1.1 0.023 14.7 1.1 1.6 1 1 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KFM59500.1 - 0.0094 16.2 4.0 0.064 13.6 0.3 2.1 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 KFM59500.1 - 0.0094 16.7 1.3 0.012 16.4 1.3 1.1 1 0 0 1 1 1 1 zinc-ribbon family zf-BED PF02892.15 KFM59500.1 - 0.012 15.7 1.6 0.012 15.7 1.6 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_8 PF15909.5 KFM59500.1 - 0.012 15.8 3.3 0.015 15.6 3.3 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon Zf_RING PF16744.5 KFM59500.1 - 0.013 15.6 3.1 0.73 10.0 0.3 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger C1_4 PF07975.12 KFM59500.1 - 0.013 15.7 2.0 0.018 15.2 2.0 1.3 1 0 0 1 1 1 0 TFIIH C1-like domain zinc-ribbons_6 PF07191.12 KFM59500.1 - 0.014 15.4 4.5 0.065 13.2 4.7 1.8 1 1 1 2 2 2 0 zinc-ribbons DUF2256 PF10013.9 KFM59500.1 - 0.014 15.5 1.7 0.84 9.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C4_ClpX PF06689.13 KFM59500.1 - 0.021 14.7 0.7 0.91 9.5 0.0 2.1 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-MYST PF17772.1 KFM59500.1 - 0.029 14.0 3.5 0.053 13.1 0.2 2.0 1 1 1 2 2 2 0 MYST family zinc finger domain HNH_5 PF14279.6 KFM59500.1 - 0.035 14.0 3.8 0.91 9.4 3.8 2.1 1 1 0 1 1 1 0 HNH endonuclease Prok-RING_1 PF14446.6 KFM59500.1 - 0.035 14.0 1.5 4 7.4 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2_9 PF16293.5 KFM59500.1 - 0.036 13.9 1.1 2.4 8.1 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-FPG_IleRS PF06827.14 KFM59500.1 - 0.037 13.9 0.2 0.037 13.9 0.2 1.9 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-LYAR PF08790.11 KFM59500.1 - 0.039 13.9 2.7 1.9 8.4 0.3 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger LIM PF00412.22 KFM59500.1 - 0.099 12.9 5.3 4.6 7.6 0.4 2.1 1 1 0 1 1 1 0 LIM domain DNA_RNApol_7kD PF03604.13 KFM59500.1 - 0.11 12.2 1.8 7.5 6.3 0.2 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-CCHC_2 PF13696.6 KFM59500.1 - 0.11 12.3 6.6 0.8 9.6 0.7 2.3 2 0 0 2 2 2 0 Zinc knuckle Vps39_2 PF10367.9 KFM59500.1 - 0.14 12.6 4.4 2.6 8.6 0.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-HIT PF04438.16 KFM59500.1 - 0.16 11.9 4.3 1.4 8.9 0.5 2.2 2 0 0 2 2 2 0 HIT zinc finger TRAF6_Z2 PF18048.1 KFM59500.1 - 0.16 12.1 1.2 0.16 12.1 1.2 2.6 3 0 0 3 3 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-AN1 PF01428.16 KFM59500.1 - 0.23 11.6 6.8 1.6 9.0 0.9 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HC_2 PF13913.6 KFM59500.1 - 0.32 10.9 0.7 0.32 10.9 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF629 PF04780.12 KFM59500.1 - 1.4 7.3 6.6 2 6.8 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.6 KFM59501.1 - 2.8e-12 46.4 7.8 1.4e-09 37.9 1.3 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-met PF12874.7 KFM59501.1 - 1.4e-08 34.8 5.9 3.2e-05 24.2 0.6 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFM59501.1 - 2.7e-08 33.8 8.7 3.6e-07 30.3 1.6 2.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59501.1 - 9e-07 29.2 13.1 1.8e-05 25.2 1.2 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM59501.1 - 3e-05 24.2 4.1 0.032 14.5 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFM59501.1 - 0.0054 16.3 2.5 0.91 9.2 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 KFM59501.1 - 0.0055 16.6 1.8 1.4 8.9 0.1 2.1 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 C1_1 PF00130.22 KFM59501.1 - 0.0072 16.2 4.1 0.043 13.7 4.1 1.9 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2197 PF09963.9 KFM59501.1 - 0.0076 16.5 2.9 0.03 14.6 0.2 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2H2_6 PF13912.6 KFM59501.1 - 0.0094 15.9 0.4 0.0094 15.9 0.4 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFM59501.1 - 0.01 15.7 5.6 0.11 12.4 0.5 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DZR PF12773.7 KFM59501.1 - 0.016 15.2 0.6 0.018 15.1 0.6 1.1 1 0 0 1 1 1 0 Double zinc ribbon Baculo_IE-1 PF05290.11 KFM59501.1 - 0.021 14.8 1.0 2.7 7.9 0.1 2.0 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF2256 PF10013.9 KFM59501.1 - 0.023 14.8 2.2 3.8 7.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 KFM59501.1 - 0.024 15.1 4.5 0.11 12.9 0.6 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KFM59501.1 - 0.034 14.3 2.6 0.15 12.2 2.6 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 KFM59501.1 - 0.043 13.8 3.0 0.18 11.8 2.8 1.8 1 1 1 2 2 2 0 zinc-ribbons Vps39_2 PF10367.9 KFM59501.1 - 0.068 13.6 4.4 3.4 8.2 0.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Zf_RING PF16744.5 KFM59501.1 - 0.12 12.5 4.0 4.9 7.4 3.1 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger HypA PF01155.19 KFM59501.1 - 0.13 12.3 1.6 1.7 8.7 0.1 1.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 KFM59501.1 - 0.4 10.9 7.0 3.3 7.9 0.9 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger DDE_3 PF13358.6 KFM59502.1 - 0.054 13.3 0.4 0.069 12.9 0.4 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_29 PF13551.6 KFM59504.1 - 1.6e-05 24.9 0.4 2.6e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM59504.1 - 0.00012 22.2 0.2 0.00019 21.6 0.2 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM59504.1 - 0.00012 21.7 0.0 0.0003 20.5 0.0 1.7 1 1 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 KFM59504.1 - 0.00055 19.8 0.1 0.0028 17.5 0.0 2.1 2 1 0 2 2 2 1 MarR family PAX PF00292.18 KFM59504.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.5 1 1 0 1 1 1 1 'Paired box' domain HTH_7 PF02796.15 KFM59504.1 - 0.0014 18.6 0.2 0.021 14.9 0.0 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM59504.1 - 0.019 15.1 0.3 0.038 14.1 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KFM59504.1 - 0.043 14.1 0.1 0.054 13.8 0.1 1.3 1 1 0 1 1 1 0 Transposase DUF2774 PF11242.8 KFM59504.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) HTH_Tnp_Tc3_2 PF01498.18 KFM59505.1 - 5e-16 58.7 3.5 6.2e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59505.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59505.1 - 3.1e-07 30.0 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59505.1 - 0.0029 17.3 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59505.1 - 2.8 8.6 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59506.1 - 3.8e-16 59.1 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59506.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59506.1 - 3.1e-07 30.0 1.6 7.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59506.1 - 0.0014 18.3 0.7 0.0083 15.9 0.6 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59506.1 - 0.03 14.4 0.4 0.099 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM59506.1 - 2.7 8.7 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain MULE PF10551.9 KFM59508.1 - 0.015 15.7 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 MULE transposase domain SRP54 PF00448.22 KFM59508.1 - 0.098 12.3 0.0 0.1 12.2 0.0 1.0 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SR-25 PF10500.9 KFM59509.1 - 1.8 8.1 4.0 2.4 7.7 4.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 KFM59509.1 - 2.2 6.6 4.0 3 6.2 4.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF5641 PF18701.1 KFM59510.1 - 5.2e-13 49.0 0.0 8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) HTH_Tnp_Tc3_2 PF01498.18 KFM59511.1 - 2.9e-05 24.2 0.0 8.3e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM59511.1 - 0.00024 20.8 0.2 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM59511.1 - 0.0049 16.7 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 Tc3 transposase HTH_23 PF13384.6 KFM59511.1 - 0.018 14.8 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KFM59511.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF411 PF04214.13 KFM59512.1 - 0.042 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF DUF2369 PF10179.9 KFM59513.1 - 4.3e-17 62.3 0.1 6.6e-15 55.3 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 KFM59513.1 - 1.4e-07 31.8 0.8 0.14 12.5 0.2 4.1 3 1 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM59513.1 - 0.0041 17.7 0.1 0.8 10.3 0.0 2.7 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM59513.1 - 0.075 13.4 3.4 3.5 8.0 0.0 3.5 4 0 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III DCX PF03607.17 KFM59515.1 - 7.8e-31 106.0 0.3 1.1e-17 63.9 0.1 2.7 3 0 0 3 3 3 2 Doublecortin HAD_SAK_1 PF10307.9 KFM59515.1 - 0.052 13.3 0.1 0.088 12.6 0.1 1.3 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins Gal_Lectin PF02140.18 KFM59516.1 - 0.00036 20.9 0.4 0.00056 20.3 0.4 1.3 1 0 0 1 1 1 1 Galactose binding lectin domain FAM176 PF14851.6 KFM59516.1 - 0.033 13.8 0.6 0.13 11.9 0.0 1.9 1 1 1 2 2 2 0 FAM176 family DUF2207 PF09972.9 KFM59516.1 - 0.048 12.4 0.0 0.063 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Gal_Lectin PF02140.18 KFM59517.1 - 0.0065 16.9 0.5 0.0088 16.5 0.5 1.2 1 0 0 1 1 1 1 Galactose binding lectin domain RVT_1 PF00078.27 KFM59518.1 - 7.4e-09 35.5 0.0 9.3e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HHH_8 PF14716.6 KFM59520.1 - 0.021 15.2 0.4 0.06 13.7 0.1 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF5327 PF17261.2 KFM59520.1 - 7.1 7.4 8.3 6.7 7.5 0.3 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5327) HTH_Tnp_Tc3_2 PF01498.18 KFM59521.1 - 2.2e-16 59.8 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59521.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59522.1 - 8.9e-16 57.9 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59522.1 - 5.3e-15 55.4 0.1 5.5e-14 52.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59522.1 - 0.00081 20.0 1.5 0.00081 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59522.1 - 0.003 17.3 0.0 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM59522.1 - 0.026 14.5 2.1 0.045 13.8 0.2 2.4 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM59524.1 - 4.3e-16 58.9 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59524.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59524.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59524.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59524.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain 7tm_1 PF00001.21 KFM59525.1 - 2.5e-56 190.9 19.5 3.8e-56 190.3 19.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM59525.1 - 6.6e-15 55.2 18.1 8.2e-15 54.9 18.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM59525.1 - 1.5e-07 31.3 21.8 1.5e-07 31.3 21.8 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KFM59525.1 - 8.9e-06 25.2 13.8 1.6e-05 24.4 13.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFM59525.1 - 0.004 16.9 14.8 0.011 15.5 14.8 1.6 1 1 0 1 1 1 1 Olfactory receptor Pentapeptide_4 PF13599.6 KFM59525.1 - 0.042 14.0 4.5 0.13 12.5 4.4 1.8 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KFM59525.1 - 0.086 12.5 3.0 1.6 8.4 0.2 2.4 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) DDE_3 PF13358.6 KFM59526.1 - 4.5e-16 58.9 0.1 5.6e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59526.1 - 5.7e-16 58.5 6.5 1.4e-15 57.2 6.5 1.7 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM59526.1 - 0.0001 22.0 0.1 0.0053 16.5 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59526.1 - 0.00046 20.7 2.1 0.00046 20.7 2.1 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59526.1 - 0.0018 18.4 0.1 0.0075 16.4 0.1 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM59526.1 - 0.0033 17.5 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM59526.1 - 0.0038 17.2 2.5 0.0042 17.1 0.3 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM59527.1 - 2.5e-17 62.9 1.5 9.5e-16 57.8 2.2 2.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59527.1 - 2.5e-13 50.0 0.0 4.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59527.1 - 5.2e-07 29.3 1.6 1.1e-06 28.3 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59527.1 - 0.0044 16.8 0.5 0.012 15.4 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59527.1 - 0.046 13.9 0.5 0.15 12.2 0.5 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Secretin_N_2 PF07655.13 KFM59527.1 - 0.12 13.0 0.8 0.25 11.9 0.8 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain HTH_32 PF13565.6 KFM59527.1 - 7 7.4 15.8 0.2 12.3 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Glyco_hydro_18 PF00704.28 KFM59528.1 - 1.7e-07 31.3 0.0 1.9e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HTH_Tnp_Tc3_2 PF01498.18 KFM59529.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59529.1 - 1.2e-13 51.1 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59529.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59529.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59529.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF4371 PF14291.6 KFM59530.1 - 7.7e-10 38.8 0.0 2.1e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM59530.1 - 0.0085 15.9 0.2 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DDE_3 PF13358.6 KFM59531.1 - 6.4e-16 58.4 0.1 7.4e-15 55.0 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59531.1 - 8.1e-16 58.0 6.5 1.7e-15 57.0 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM59531.1 - 0.00084 19.9 1.5 0.00084 19.9 1.5 3.0 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59531.1 - 0.0033 17.2 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59531.1 - 0.017 15.3 0.1 0.074 13.2 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM59531.1 - 0.035 14.1 2.6 0.04 13.9 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix Metallophos PF00149.28 KFM59532.1 - 0.029 14.9 0.0 0.033 14.7 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos PF00149.28 KFM59533.1 - 0.087 13.3 0.0 0.098 13.1 0.0 1.0 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DUF2870 PF11069.8 KFM59534.1 - 9.9e-37 125.2 3.2 1.9e-36 124.3 3.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 KFM59534.1 - 0.008 15.9 0.1 0.023 14.5 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin family DUF5415 PF17436.2 KFM59534.1 - 4.5 7.4 8.4 0.13 12.4 1.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5415) zf-C2H2_2 PF12756.7 KFM59535.1 - 0.026 14.9 3.5 0.065 13.6 3.5 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF1699 PF08004.11 KFM59535.1 - 0.052 13.2 1.4 0.1 12.3 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) PBP1_TM PF14812.6 KFM59535.1 - 0.075 13.4 2.9 0.23 11.8 2.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HTH_Tnp_Tc3_2 PF01498.18 KFM59536.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59536.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59536.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59536.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59536.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF4817 PF16087.5 KFM59537.1 - 6.2e-10 38.7 0.0 1.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) DUF1054 PF06335.12 KFM59537.1 - 0.034 14.1 0.2 0.044 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) CENP-B_N PF04218.13 KFM59537.1 - 0.15 11.7 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM59538.1 - 5.4e-15 55.4 5.5 1.4e-14 54.1 4.1 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59538.1 - 4.4e-11 42.7 0.2 1.7e-10 40.8 0.2 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59538.1 - 7.9e-05 23.2 3.4 7.9e-05 23.2 3.4 2.4 2 0 0 2 2 2 1 Homeodomain-like domain DUF1664 PF07889.12 KFM59538.1 - 0.0015 18.6 3.5 0.0033 17.5 3.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 KFM59538.1 - 0.0056 16.6 0.6 0.011 15.7 0.6 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CENP-B_N PF04218.13 KFM59538.1 - 0.0082 15.7 0.0 0.032 13.9 0.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 KFM59538.1 - 0.011 15.9 0.6 0.085 13.0 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM59538.1 - 0.016 15.0 0.0 0.016 15.0 0.0 3.4 4 0 0 4 4 4 0 Homeodomain-like domain ABC_tran_CTD PF16326.5 KFM59538.1 - 0.026 14.8 3.1 0.16 12.2 0.1 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 KFM59538.1 - 0.038 14.2 1.8 0.061 13.5 1.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 KFM59538.1 - 0.039 14.2 0.5 0.074 13.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 KFM59538.1 - 0.079 13.4 0.1 0.18 12.3 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HTH_7 PF02796.15 KFM59538.1 - 0.11 12.6 0.1 2.6 8.2 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase Prominin PF05478.11 KFM59538.1 - 0.14 10.1 0.1 0.18 9.7 0.1 1.1 1 0 0 1 1 1 0 Prominin Prefoldin_2 PF01920.20 KFM59538.1 - 0.27 11.2 6.7 1.5 8.8 0.7 2.3 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 KFM59538.1 - 0.68 10.4 8.2 0.2 12.1 1.0 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Cation_ATPase_C PF00689.21 KFM59539.1 - 2.6e-45 154.4 0.1 3.3e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFM59539.1 - 1.2e-09 38.8 0.3 5.4e-07 30.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM59539.1 - 0.00011 22.0 0.4 0.0002 21.2 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sigma70_r4 PF04545.16 KFM59539.1 - 0.0032 17.0 0.0 0.014 14.9 0.0 2.2 1 1 0 1 1 1 1 Sigma-70, region 4 Transposase_1 PF01359.18 KFM59540.1 - 6.2e-15 54.8 0.0 1.2e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM59540.1 - 2.4e-07 30.6 0.1 3.3e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59540.1 - 0.0092 16.2 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 Transposase HTH_10 PF04967.12 KFM59540.1 - 0.034 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_24 PF13412.6 KFM59540.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DDE_1 PF03184.19 KFM59541.1 - 0.00034 20.3 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Lipase PF00151.19 KFM59543.1 - 3.8e-96 322.3 0.0 4.4e-96 322.1 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFM59543.1 - 0.00097 19.8 0.0 0.0013 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KFM59543.1 - 0.009 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 KFM59543.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM59543.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DDE_3 PF13358.6 KFM59544.1 - 1.7e-16 60.3 0.1 1.8e-15 56.9 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59544.1 - 1.4e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase Lipase PF00151.19 KFM59545.1 - 1e-97 327.5 0.0 1.2e-97 327.2 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFM59545.1 - 1.2e-06 29.1 0.1 2.2e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.7 KFM59545.1 - 0.035 14.7 0.1 0.055 14.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4795 PF16043.5 KFM59546.1 - 0.0012 18.5 6.9 0.0012 18.5 6.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) Apolipoprotein PF01442.18 KFM59546.1 - 0.003 17.5 3.7 0.0045 16.9 3.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM59546.1 - 0.0068 16.5 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 KFM59546.1 - 0.0096 16.0 6.3 0.021 14.9 6.3 1.5 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF1640 PF07798.11 KFM59546.1 - 0.021 14.9 5.9 0.029 14.4 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1451 PF07295.11 KFM59546.1 - 0.042 13.9 2.5 0.071 13.1 2.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Serine_rich PF08824.10 KFM59546.1 - 0.063 13.3 1.0 0.092 12.7 1.0 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF4510 PF14971.6 KFM59546.1 - 0.1 12.9 0.3 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DUF883 PF05957.13 KFM59546.1 - 0.23 12.1 3.8 0.75 10.4 3.8 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) tRNA_bind_2 PF13725.6 KFM59546.1 - 0.45 10.2 7.5 0.73 9.5 7.5 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain CdvA PF18822.1 KFM59546.1 - 0.73 9.7 9.1 3.2 7.6 7.6 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Seryl_tRNA_N PF02403.22 KFM59546.1 - 1.3 9.3 8.7 6.5 7.0 8.7 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 KFM59546.1 - 3.3 7.8 10.5 3.8 7.6 0.7 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YtxH PF12732.7 KFM59546.1 - 3.3 8.3 12.5 29 5.3 12.5 2.2 1 1 0 1 1 1 0 YtxH-like protein Dynamitin PF04912.14 KFM59546.1 - 3.7 6.8 11.0 1.5 8.0 4.6 2.1 1 1 1 2 2 2 0 Dynamitin PKK PF12474.8 KFM59546.1 - 7.8 6.6 12.5 0.43 10.7 7.3 1.5 2 0 0 2 2 2 0 Polo kinase kinase Lipase PF00151.19 KFM59547.1 - 5.4e-99 331.7 0.0 6.7e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFM59547.1 - 1.1e-09 38.9 0.1 1.9e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.7 KFM59547.1 - 0.0081 16.8 0.0 0.013 16.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KFM59547.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase HTH_Tnp_Tc3_2 PF01498.18 KFM59548.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59548.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM59549.1 - 4.9e-10 39.3 0.0 6.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 KFM59549.1 - 0.00085 19.4 0.2 0.0018 18.3 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM59549.1 - 0.0019 18.4 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_3 PF01381.22 KFM59549.1 - 0.0027 17.7 0.0 0.0065 16.5 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix Sigma70_r4 PF04545.16 KFM59549.1 - 0.021 14.3 0.1 0.053 13.1 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 KFM59549.1 - 0.033 14.0 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59550.1 - 3.4e-16 59.2 3.4 5.2e-16 58.7 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59550.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59550.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59550.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59550.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Aldo_ket_red PF00248.21 KFM59551.1 - 6.4e-17 61.7 0.0 7.4e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_Tc3_2 PF01498.18 KFM59553.1 - 1.6e-16 60.3 1.4 3.4e-16 59.2 1.4 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM59553.1 - 2.1e-05 25.1 10.4 3.1e-05 24.5 5.9 2.2 2 0 0 2 2 2 1 Homeodomain-like domain PAX PF00292.18 KFM59553.1 - 0.00012 22.0 0.1 0.00018 21.4 0.1 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.6 KFM59553.1 - 0.00013 22.0 3.4 0.018 15.2 0.1 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_29 PF13551.6 KFM59553.1 - 0.00059 19.8 0.9 0.029 14.4 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 KFM59553.1 - 0.0052 16.4 0.1 0.013 15.1 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KFM59553.1 - 0.01 15.6 7.5 1.3 9.0 0.1 3.4 2 1 0 2 2 2 0 Homeodomain-like domain MarR_2 PF12802.7 KFM59553.1 - 0.021 14.7 1.4 0.14 12.0 0.1 2.3 2 0 0 2 2 2 0 MarR family HTH_3 PF01381.22 KFM59553.1 - 0.023 14.7 1.7 0.33 11.1 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix HTH_22 PF13309.6 KFM59553.1 - 0.034 14.2 0.1 0.087 12.9 0.1 1.7 1 0 0 1 1 1 0 HTH domain HTH_37 PF13744.6 KFM59553.1 - 0.038 14.0 0.0 9.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 KFM59553.1 - 0.063 13.2 0.1 7.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_21 PF13276.6 KFM59553.1 - 0.17 12.0 1.7 0.56 10.4 1.7 2.1 1 1 0 1 1 1 0 HTH-like domain HTH_38 PF13936.6 KFM59553.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.9 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_7 PF02796.15 KFM59553.1 - 0.67 10.1 4.0 1.3 9.1 2.4 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase FANCI_S2 PF14676.6 KFM59554.1 - 0.053 13.8 1.6 0.17 12.2 1.6 1.9 1 0 0 1 1 1 0 FANCI solenoid 2 RNA_pol_Rpb2_1 PF04563.15 KFM59555.1 - 3.3e-48 163.9 0.1 4.2e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_6 PF00562.28 KFM59556.1 - 1.1e-122 409.9 0.0 1.4e-122 409.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_4 PF04566.13 KFM59556.1 - 5.2e-26 90.7 0.5 1.1e-25 89.7 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_7 PF04560.20 KFM59556.1 - 5e-22 78.1 0.1 9.9e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KFM59556.1 - 1.5e-20 73.1 0.0 3.9e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFM59556.1 - 1.7e-11 44.5 0.3 4.5e-11 43.2 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_2 PF04561.14 KFM59556.1 - 1.4e-07 31.3 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 HTH_Tnp_Tc3_2 PF01498.18 KFM59557.1 - 2.2e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59557.1 - 8.6e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease JHBP PF06585.11 KFM59558.1 - 2.8e-30 105.3 5.6 2.5e-26 92.4 1.5 2.1 2 0 0 2 2 2 2 Haemolymph juvenile hormone binding protein (JHBP) Grp7_allergen PF16984.5 KFM59558.1 - 6.1e-23 81.8 0.7 1.9e-22 80.2 0.1 2.0 2 0 0 2 2 2 1 Group 7 allergen zinc_ribbon_9 PF14369.6 KFM59559.1 - 1.7e-13 50.6 2.4 2.5e-13 50.1 2.4 1.3 1 0 0 1 1 1 1 zinc-ribbon TF_Zn_Ribbon PF08271.12 KFM59559.1 - 0.0024 17.3 1.9 0.0024 17.3 1.9 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Anti-TRAP PF15777.5 KFM59559.1 - 0.014 15.4 0.3 0.024 14.6 0.3 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFM59559.1 - 0.015 15.3 0.2 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KFM59559.1 - 0.058 13.5 1.9 0.098 12.8 1.9 1.4 1 0 0 1 1 1 0 Zinc ribbon domain HTH_Tnp_Tc3_2 PF01498.18 KFM59560.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59560.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59560.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59560.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59560.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59561.1 - 2.4e-16 59.7 2.2 4.4e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59561.1 - 9.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59562.1 - 2.4e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59562.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59563.1 - 4.8e-16 58.8 3.5 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59563.1 - 3.8e-11 42.9 0.0 6.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59563.1 - 2.8e-07 30.2 1.6 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59563.1 - 0.0027 17.5 0.6 0.0074 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59563.1 - 0.029 14.5 0.4 0.089 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM59563.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59564.1 - 2.6e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59564.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59564.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59564.1 - 0.0023 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59564.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59565.1 - 2.3e-16 59.8 2.2 6.4e-16 58.4 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59565.1 - 3.2e-14 52.9 0.0 5.5e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59565.1 - 2.5e-07 30.4 1.2 7.8e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59565.1 - 0.0031 17.3 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59565.1 - 3.2 8.4 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Trypsin PF00089.26 KFM59566.1 - 3.9e-47 160.9 1.5 4.8e-47 160.6 1.5 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM59566.1 - 2.8e-08 34.8 0.1 4.1e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ldl_recept_a PF00057.18 KFM59566.1 - 1.3e-05 25.3 14.3 1.3e-05 25.3 14.3 2.0 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 KFM59566.1 - 0.0095 16.3 0.1 0.046 14.1 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFM59567.1 - 6.4e-45 153.7 1.9 8.5e-45 153.3 1.9 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM59567.1 - 2.1e-06 28.7 0.0 3.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM59567.1 - 4.5e-06 27.0 0.0 1.3e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.18 KFM59567.1 - 8.9e-06 25.8 14.8 8.9e-06 25.8 14.8 1.9 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFM59567.1 - 0.061 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 CUB domain Ig_3 PF13927.6 KFM59568.1 - 2.2e-09 37.8 0.0 2.5e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM59568.1 - 8.9e-07 28.9 0.0 1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM59568.1 - 4.3e-05 23.6 0.0 5.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM59568.1 - 0.0012 19.2 0.0 0.0013 19.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM59568.1 - 0.094 12.8 0.1 0.095 12.8 0.1 1.3 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM59568.1 - 0.19 11.9 0.4 0.65 10.2 0.1 1.8 1 1 1 2 2 2 0 Immunoglobulin V-set domain I-set PF07679.16 KFM59569.1 - 1e-18 67.1 0.0 3e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM59569.1 - 1.3e-15 57.8 0.0 2e-07 31.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM59569.1 - 2.9e-11 43.5 0.2 0.0012 19.0 0.0 3.7 2 2 2 4 4 4 3 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM59569.1 - 8e-09 35.7 0.0 0.00021 21.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM59569.1 - 1.7e-08 34.5 0.0 6.1e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 KFM59569.1 - 0.002 18.3 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFM59569.1 - 0.017 14.6 0.0 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFM59569.1 - 0.13 12.4 0.0 3.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 KFM59570.1 - 0.00029 21.4 0.0 0.00036 21.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM59570.1 - 0.00031 20.8 0.0 0.0004 20.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM59570.1 - 0.0031 17.8 0.0 0.004 17.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM59570.1 - 0.012 15.7 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFM59570.1 - 0.013 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain BiPBP_C PF06832.12 KFM59570.1 - 0.063 13.3 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family DUF2465 PF10239.9 KFM59571.1 - 5.5e-26 91.6 0.6 6.1e-26 91.4 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) DUF2465 PF10239.9 KFM59572.1 - 2.5e-70 237.3 0.1 2.8e-70 237.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Ndc80_HEC PF03801.13 KFM59572.1 - 0.11 12.1 0.0 0.42 10.2 0.0 1.9 1 1 0 1 1 1 0 HEC/Ndc80p family HTH_Tnp_Tc3_2 PF01498.18 KFM59573.1 - 2e-19 69.6 3.6 6e-19 68.1 2.1 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59573.1 - 5.1e-16 58.7 0.0 2.4e-15 56.6 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM59573.1 - 2.4e-07 30.7 0.4 0.00015 21.8 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM59573.1 - 3.7e-07 30.6 2.0 3.7e-07 30.6 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59573.1 - 1e-06 28.7 2.3 7.9e-05 22.7 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59573.1 - 2e-06 27.4 3.3 2.6e-05 23.9 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM59573.1 - 3.1e-06 27.1 0.7 4.2e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM59573.1 - 0.00013 21.8 0.7 0.0018 18.1 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM59573.1 - 0.0012 18.8 0.3 0.017 15.1 0.0 2.4 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM59573.1 - 0.021 14.5 0.1 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM59573.1 - 0.04 14.0 0.1 2.1 8.5 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM59573.1 - 0.096 12.9 0.1 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 KFM59573.1 - 0.15 12.1 0.0 31 4.8 0.0 2.6 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM59573.1 - 0.31 10.9 3.8 1.5 8.7 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM59573.1 - 1.2 8.6 3.6 7.4 6.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc3_2 PF01498.18 KFM59574.1 - 2.5e-16 59.6 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59574.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59574.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59574.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59574.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Exo_endo_phos_2 PF14529.6 KFM59575.1 - 3.5e-13 49.5 1.0 3.5e-13 49.5 1.0 2.7 2 1 1 3 3 3 1 Endonuclease-reverse transcriptase zf-CCHC_6 PF15288.6 KFM59575.1 - 1.5e-08 34.3 4.2 0.00061 19.6 0.2 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 KFM59575.1 - 1.2e-06 28.3 5.7 0.00038 20.4 1.8 2.5 2 0 0 2 2 2 2 Zinc knuckle gag-asp_proteas PF13975.6 KFM59575.1 - 0.00017 22.1 0.0 0.00044 20.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM59575.1 - 0.0004 21.0 0.0 0.0008 20.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_4 PF14392.6 KFM59575.1 - 0.012 15.3 1.9 0.41 10.4 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle HscB_4_cys PF18256.1 KFM59575.1 - 0.027 14.3 1.2 0.027 14.3 1.2 3.3 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif Exo_endo_phos PF03372.23 KFM59575.1 - 0.035 13.6 0.0 0.063 12.8 0.0 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family HTH_46 PF15977.5 KFM59575.1 - 0.12 12.4 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding HTH_Tnp_Tc3_2 PF01498.18 KFM59576.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59576.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Cadherin_C_2 PF16492.5 KFM59577.1 - 0.05 14.4 0.1 0.33 11.7 0.1 2.0 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Adaptin_binding PF10199.9 KFM59578.1 - 6.6e-17 62.2 2.4 8.6e-17 61.9 2.4 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 HTH_Tnp_Tc3_2 PF01498.18 KFM59579.1 - 2.5e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59579.1 - 9.6e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59580.1 - 4.5e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59580.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59580.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59580.1 - 0.0025 17.6 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59580.1 - 2.1 9.0 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain KdpC PF02669.15 KFM59581.1 - 0.059 13.2 0.3 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 K+-transporting ATPase, c chain Drf_GBD PF06371.13 KFM59582.1 - 3.2e-16 59.5 0.3 5.2e-16 58.8 0.3 1.4 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KFM59583.1 - 6.9e-52 175.9 1.9 9.9e-52 175.4 1.9 1.2 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFM59583.1 - 3.4e-07 30.0 0.9 1.8e-06 27.6 0.1 2.4 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain MscS_porin PF12795.7 KFM59583.1 - 0.014 15.0 0.5 0.014 15.0 0.5 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Stathmin PF00836.19 KFM59583.1 - 0.021 14.8 1.0 0.039 13.9 1.0 1.4 1 0 0 1 1 1 0 Stathmin family Drf_FH1 PF06346.12 KFM59583.1 - 0.03 14.0 102.6 0.052 13.3 102.6 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 UPF0242 PF06785.11 KFM59583.1 - 0.046 13.8 8.3 0.092 12.8 2.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF29 PF01724.16 KFM59583.1 - 0.059 13.6 1.2 0.12 12.6 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF29 PilJ PF13675.6 KFM59583.1 - 0.11 12.6 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3361 PF11841.8 KFM59583.1 - 0.14 12.1 0.2 0.93 9.4 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) KxDL PF10241.9 KFM59583.1 - 0.18 12.1 2.2 0.37 11.1 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein FH2 PF02181.23 KFM59584.1 - 5.7e-82 275.8 17.5 5.7e-82 275.8 17.5 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_DAD PF06345.11 KFM59584.1 - 3.7e-07 29.7 0.8 9.9e-07 28.4 0.8 1.8 1 0 0 1 1 1 1 DRF Autoregulatory Domain PMEI PF04043.15 KFM59584.1 - 0.0061 16.9 1.3 0.011 16.1 0.5 1.8 1 1 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor SpoIIAA-like PF11964.8 KFM59584.1 - 1.7 9.7 5.9 4.3 8.4 0.4 3.1 2 1 1 3 3 3 0 SpoIIAA-like DUF445 PF04286.12 KFM59584.1 - 4.7 6.9 13.6 3 7.6 11.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF445) START PF01852.19 KFM59586.1 - 5.6e-06 25.9 0.0 6.6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 START domain DDE_1 PF03184.19 KFM59587.1 - 2.9e-05 23.8 1.2 3.1e-05 23.7 1.2 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease SecM PF06558.12 KFM59587.1 - 0.12 12.5 1.0 0.13 12.4 1.0 1.1 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) CPG4 PF15481.6 KFM59589.1 - 0.094 13.4 8.3 0.13 12.9 6.0 2.1 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 CPG4 PF15481.6 KFM59592.1 - 0.74 10.5 4.0 0.4 11.3 1.1 1.9 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 RVT_1 PF00078.27 KFM59595.1 - 9.1e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFCD_C PF12612.8 KFM59595.1 - 0.062 13.1 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal HTH_Tnp_Tc3_2 PF01498.18 KFM59596.1 - 2.5e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59596.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59597.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59597.1 - 1.4e-12 47.6 0.0 2.5e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59597.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59597.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59597.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF1759 PF03564.15 KFM59598.1 - 5.9e-07 29.5 0.7 7.6e-07 29.2 0.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Sterile PF03015.19 KFM59598.1 - 0.055 13.7 0.1 0.09 13.0 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein HTH_Tnp_Tc3_2 PF01498.18 KFM59600.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59600.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease C2-set_2 PF08205.12 KFM59601.1 - 1.4e-11 44.3 0.1 1.8e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFM59601.1 - 5.1e-07 29.8 0.1 6.3e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM59601.1 - 3.5e-06 27.5 0.1 4.3e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM59601.1 - 2.7e-05 24.4 0.0 3.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM59601.1 - 0.0075 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain C1-set PF07654.15 KFM59601.1 - 0.017 15.5 0.0 0.018 15.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin C1-set domain DUF775 PF05603.12 KFM59603.1 - 5.6e-45 153.3 1.8 1e-44 152.5 1.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Fibrinogen_C PF00147.18 KFM59604.1 - 1e-67 228.2 10.5 1.3e-67 227.9 10.5 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PHD PF00628.29 KFM59605.1 - 1.4e-14 53.7 22.7 5.2e-08 32.7 8.2 2.4 1 1 1 2 2 2 2 PHD-finger SAM_1 PF00536.30 KFM59605.1 - 2e-07 31.3 0.0 4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM59605.1 - 2.5e-07 30.7 0.0 6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) C1_1 PF00130.22 KFM59605.1 - 0.0007 19.4 1.7 0.0007 19.4 1.7 3.1 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KFM59605.1 - 0.0012 18.9 6.6 0.0012 18.9 6.6 2.9 1 1 1 2 2 2 1 PHD-finger SAM_PNT PF02198.16 KFM59605.1 - 0.0056 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Prok-RING_1 PF14446.6 KFM59605.1 - 0.098 12.6 21.4 0.4 10.6 0.8 3.8 1 1 2 3 3 3 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KFM59605.1 - 0.77 9.4 18.3 1 9.0 3.1 3.0 2 1 0 2 2 2 0 PHD-finger A2L_zn_ribbon PF08792.10 KFM59605.1 - 0.78 9.5 8.2 4.7 7.0 0.2 3.6 3 0 0 3 3 3 0 A2L zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 KFM59605.1 - 1.2 9.1 8.2 15 5.7 0.1 3.6 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Zf_RING PF16744.5 KFM59605.1 - 1.9 8.6 22.1 2.5 8.3 13.8 3.3 1 1 1 2 2 2 0 KIAA1045 RING finger C1_2 PF03107.16 KFM59605.1 - 2.8 8.3 19.2 1.7 9.1 0.7 3.4 3 0 0 3 3 3 0 C1 domain ADK PF00406.22 KFM59606.1 - 1.5e-44 151.7 0.0 1.8e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFM59606.1 - 2.3e-21 76.6 0.0 1.1e-20 74.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 KFM59606.1 - 2.5e-14 52.9 0.0 3.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KFM59606.1 - 5.3e-08 33.5 0.0 1.1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM59606.1 - 0.00077 19.6 0.0 0.0071 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFM59606.1 - 0.0067 16.2 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Peptidase_C54 PF03416.19 KFM59607.1 - 2.3e-97 325.7 0.0 3.4e-97 325.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 DUF974 PF06159.13 KFM59608.1 - 7.3e-83 278.1 0.1 9.4e-83 277.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Transglut_C PF00927.22 KFM59608.1 - 0.039 14.1 0.8 21 5.3 0.0 3.2 3 1 1 4 4 4 0 Transglutaminase family, C-terminal ig like domain COesterase PF00135.28 KFM59610.1 - 6.8e-51 173.7 0.0 7.7e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM59610.1 - 0.014 15.3 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 KFM59611.1 - 1e-27 97.2 0.0 1.1e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family F-box PF00646.33 KFM59612.1 - 8.1e-10 38.3 1.4 3.1e-09 36.5 1.4 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFM59612.1 - 1.1e-08 34.9 1.3 2.5e-08 33.7 1.3 1.7 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KFM59612.1 - 0.073 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 F-box LRR_4 PF12799.7 KFM59612.1 - 0.74 10.3 10.3 0.34 11.4 1.8 3.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) MRVI1 PF05781.12 KFM59614.1 - 0.047 12.4 1.3 0.055 12.1 1.3 1.2 1 0 0 1 1 1 0 MRVI1 protein COesterase PF00135.28 KFM59615.1 - 4.5e-42 144.6 0.0 5.5e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family HTH_Tnp_Tc3_2 PF01498.18 KFM59616.1 - 2.6e-14 53.2 1.0 4.8e-14 52.4 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59616.1 - 8.4e-14 51.5 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Tudor_4 PF18358.1 KFM59618.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain KA1 PF02149.19 KFM59619.1 - 0.0081 15.9 0.0 0.033 14.0 0.0 2.0 2 0 0 2 2 2 1 Kinase associated domain 1 Pkinase PF00069.25 KFM59621.1 - 7.4e-28 97.6 0.3 7.9e-28 97.5 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM59621.1 - 8.1e-15 54.8 0.1 8.7e-15 54.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM59621.1 - 8.8e-05 22.5 0.1 0.0058 16.6 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family YcxB PF14317.6 KFM59621.1 - 0.0043 16.7 0.2 0.0056 16.4 0.2 1.2 1 0 0 1 1 1 1 YcxB-like protein Kdo PF06293.14 KFM59621.1 - 0.016 14.6 0.0 0.016 14.6 0.0 1.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_Tnp_IS240 PF13610.6 KFM59621.1 - 0.066 13.4 0.0 0.079 13.2 0.0 1.2 1 0 0 1 1 1 0 DDE domain Choline_kinase PF01633.20 KFM59621.1 - 0.14 11.8 0.4 0.33 10.5 0.4 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase STT3 PF02516.14 KFM59622.1 - 4.7e-115 385.3 35.6 2.1e-111 373.3 31.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Cortexin PF11057.8 KFM59622.1 - 0.13 12.1 0.5 4.4 7.2 0.1 2.8 2 0 0 2 2 2 0 Cortexin of kidney Asparaginase PF00710.20 KFM59623.1 - 0.00025 20.6 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase PF00710.20 KFM59624.1 - 1.3e-51 174.8 0.0 2.2e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Ank_4 PF13637.6 KFM59624.1 - 2.4e-20 72.6 3.1 1.3e-10 41.6 0.2 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM59624.1 - 5.5e-16 58.9 0.7 5.2e-14 52.6 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Asparaginase_C PF17763.1 KFM59624.1 - 1.3e-15 57.6 0.0 3.6e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank PF00023.30 KFM59624.1 - 1.8e-13 50.3 2.8 6.3e-08 32.7 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KFM59624.1 - 1.1e-12 47.0 2.5 2.5e-07 30.5 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFM59624.1 - 1e-11 44.8 2.1 1.6e-08 34.6 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) HTH_Tnp_Tc3_2 PF01498.18 KFM59625.1 - 2e-16 60.0 2.2 4.5e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59625.1 - 9.7e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59626.1 - 3.2e-16 59.3 3.1 4e-16 59.0 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59626.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM59627.1 - 4e-10 39.6 0.0 4.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease LIDHydrolase PF10230.9 KFM59628.1 - 1.4e-70 237.9 0.0 1.7e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 KFM59628.1 - 7e-05 22.6 0.0 0.018 14.7 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM59628.1 - 0.00088 19.9 0.0 0.001 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Far-17a_AIG1 PF04750.14 KFM59628.1 - 0.017 14.4 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein Ser_hydrolase PF06821.13 KFM59628.1 - 0.038 13.9 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.8 KFM59628.1 - 0.078 12.2 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LCAT PF02450.15 KFM59628.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Jagunal PF07086.12 KFM59629.1 - 9.6e-57 192.1 4.0 1.1e-56 191.9 4.0 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis DUF3377 PF11857.8 KFM59629.1 - 0.0034 17.3 0.6 1.8 8.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3377) SpoV PF08183.11 KFM59629.1 - 0.07 13.1 2.2 0.18 11.8 2.2 1.8 1 0 0 1 1 1 0 Stage V sporulation protein family DUF4112 PF13430.6 KFM59629.1 - 0.078 13.3 2.9 0.41 10.9 0.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4112) HTH_Tnp_Tc3_2 PF01498.18 KFM59630.1 - 4.1e-16 59.0 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59630.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59630.1 - 1.9e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59630.1 - 0.0025 17.6 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59630.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain rve PF00665.26 KFM59631.1 - 4.2e-09 36.6 0.0 1.1e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 KFM59631.1 - 1.8e-08 34.1 0.3 4.7e-08 32.8 0.3 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-C2H2 PF00096.26 KFM59632.1 - 5.6e-16 58.0 23.6 3e-06 27.4 2.7 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM59632.1 - 4.2e-13 49.1 8.7 2e-08 34.3 2.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM59632.1 - 2.4e-06 27.9 24.8 0.00078 20.1 2.0 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM59632.1 - 0.0027 17.7 0.9 0.0027 17.7 0.9 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM59632.1 - 0.013 15.2 1.7 0.013 15.2 1.7 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-met PF12874.7 KFM59632.1 - 0.064 13.7 0.3 0.064 13.7 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM59632.1 - 0.086 13.2 0.2 0.086 13.2 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KFM59632.1 - 0.088 13.4 5.6 2.5 8.8 0.1 2.9 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF3850 PF12961.7 KFM59632.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3850) zf-TAZ PF02135.16 KFM59632.1 - 1.6 9.3 6.6 7.9 7.0 6.4 2.2 1 1 1 2 2 2 0 TAZ zinc finger zf-BED PF02892.15 KFM59632.1 - 2.6 8.1 10.7 0.2 11.7 0.8 3.2 3 0 0 3 3 3 0 BED zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM59633.1 - 8.4e-13 48.4 0.2 1.8e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59633.1 - 1.4e-09 37.9 0.0 3e-09 36.8 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59633.1 - 0.00016 22.2 2.5 0.28 11.8 0.1 3.5 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 KFM59633.1 - 0.00042 20.4 0.2 0.02 15.0 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KFM59633.1 - 0.00069 19.6 0.4 0.022 14.8 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_20 PF12840.7 KFM59633.1 - 0.0089 16.1 0.2 1.3 9.1 0.1 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59633.1 - 0.01 15.6 0.1 0.52 10.2 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM59633.1 - 0.013 15.5 0.4 0.21 11.6 0.0 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM59633.1 - 0.038 13.6 0.3 0.54 9.9 0.0 2.7 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 KFM59633.1 - 0.064 13.7 0.3 17 6.0 0.2 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain MarR_2 PF12802.7 KFM59633.1 - 0.068 13.1 0.4 2.7 8.0 0.0 2.8 3 0 0 3 3 3 0 MarR family BNR_2 PF13088.6 KFM59633.1 - 0.078 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain Methyltransf_11 PF08241.12 KFM59634.1 - 4.3e-10 40.1 0.0 1.3e-09 38.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM59634.1 - 2.3e-07 31.4 0.0 7.1e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFM59634.1 - 0.0014 18.6 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.12 KFM59634.1 - 0.0016 19.2 0.0 0.006 17.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM59634.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KFM59634.1 - 0.052 12.9 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TF_Zn_Ribbon PF08271.12 KFM59634.1 - 0.19 11.3 4.6 0.73 9.4 4.6 2.0 1 0 0 1 1 1 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 KFM59634.1 - 0.23 11.4 4.7 0.65 10.0 4.7 1.8 1 0 0 1 1 1 0 Nudix N-terminal LIAS_N PF16881.5 KFM59635.1 - 5.3e-32 110.5 0.4 1.6e-31 108.9 0.2 1.8 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KFM59635.1 - 7.6e-14 52.4 0.1 1.1e-13 51.9 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF2785 PF10978.8 KFM59635.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) Ribosomal_L32e PF01655.18 KFM59636.1 - 2.2e-44 150.3 2.2 2.6e-44 150.0 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 ATP_bind_1 PF03029.17 KFM59637.1 - 5.8e-84 281.6 0.2 6.9e-84 281.4 0.2 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KFM59637.1 - 0.00069 18.7 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 KFM59637.1 - 0.0061 16.5 0.1 0.15 11.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KFM59637.1 - 0.019 15.4 0.0 0.095 13.1 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFM59637.1 - 0.041 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFM59637.1 - 0.042 13.8 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFM59637.1 - 0.046 14.3 0.1 0.12 12.9 0.0 1.9 2 2 0 2 2 2 0 AAA domain CbiA PF01656.23 KFM59637.1 - 0.071 13.2 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AdoHcyase_NAD PF00670.21 KFM59637.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AAA_22 PF13401.6 KFM59637.1 - 0.086 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFM59637.1 - 0.092 12.5 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFM59637.1 - 0.092 12.7 0.1 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 NTPase Ribosomal_L7Ae PF01248.26 KFM59637.1 - 0.11 12.3 0.0 5.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AAA_16 PF13191.6 KFM59637.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Melibiase_2 PF16499.5 KFM59638.1 - 2.4e-48 164.7 1.1 3.1e-48 164.4 1.1 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 KFM59638.1 - 8.2e-15 54.8 0.0 1.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 KFM59638.1 - 5.3e-08 32.8 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Frataxin_Cyay PF01491.16 KFM59638.1 - 0.09 12.9 0.1 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Frataxin-like domain DUF5641 PF18701.1 KFM59639.1 - 5.7e-22 77.7 0.0 7.7e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) MreC PF04085.14 KFM59639.1 - 0.051 13.5 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 rod shape-determining protein MreC HTH_Tnp_Tc3_2 PF01498.18 KFM59640.1 - 2.2e-16 59.9 2.2 4.7e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59640.1 - 3.1e-13 49.7 0.0 5.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59641.1 - 2.2e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59641.1 - 9.8e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Cation_ATPase PF13246.6 KFM59643.1 - 3.4e-08 33.5 0.0 4.1e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Cation transport ATPase (P-type) PDZ PF00595.24 KFM59646.1 - 3.2e-11 43.4 0.3 9e-11 42.0 0.1 1.8 1 1 1 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFM59646.1 - 2.4e-08 33.7 0.1 3.5e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM59646.1 - 0.0013 19.0 0.1 0.0022 18.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFM59646.1 - 0.022 14.7 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain fn3 PF00041.21 KFM59647.1 - 1.1e-34 118.6 1.3 2.3e-12 47.1 0.4 5.6 4 1 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM59647.1 - 1.1e-15 58.0 2.0 0.0046 17.5 0.0 4.8 4 2 0 4 4 4 4 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM59647.1 - 8.5e-05 22.8 3.2 0.36 11.2 0.1 4.1 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFM59647.1 - 0.00068 20.0 0.0 11 6.5 0.0 4.1 3 1 1 4 4 4 2 Uncharacterised conserved protein (DUF2369) Big_5 PF13205.6 KFM59647.1 - 0.12 13.1 0.0 6.4 7.5 0.0 3.3 3 1 0 3 3 3 0 Bacterial Ig-like domain fn3 PF00041.21 KFM59648.1 - 1.4e-38 131.1 1.6 1e-08 35.4 0.1 5.0 4 1 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM59648.1 - 5.3e-14 52.6 2.6 0.012 16.2 0.1 4.9 4 1 0 4 4 4 4 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFM59648.1 - 4.4e-07 30.2 0.0 2.8 8.4 0.0 4.3 3 1 1 4 4 4 3 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFM59648.1 - 4.8e-06 26.8 1.9 1.3 9.3 0.0 4.3 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.6 KFM59648.1 - 5.7e-05 23.3 0.3 0.53 10.5 0.1 3.5 4 0 0 4 4 4 2 SusE outer membrane protein PhoD_N PF16655.5 KFM59648.1 - 0.00025 21.5 0.0 0.089 13.3 0.0 3.7 3 1 0 3 3 3 1 PhoD-like phosphatase, N-terminal domain Kelch_1 PF01344.25 KFM59649.1 - 2e-26 91.3 2.8 2.9e-11 42.8 0.0 4.9 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KFM59649.1 - 1.4e-23 82.3 0.3 1.1e-06 28.7 0.0 5.3 1 1 3 4 4 4 4 Kelch motif Kelch_2 PF07646.15 KFM59649.1 - 8.4e-15 54.1 0.9 1.6e-05 24.7 0.0 5.0 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KFM59649.1 - 2.6e-12 46.7 0.6 0.041 14.2 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain BACK PF07707.15 KFM59649.1 - 3.8e-08 33.4 0.3 6.8e-08 32.5 0.3 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFM59649.1 - 2.3e-07 30.7 0.0 0.0071 16.3 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM59649.1 - 0.081 12.9 0.1 0.79 9.8 0.0 2.6 3 0 0 3 3 3 0 Kelch motif FANCI_S1-cap PF14674.6 KFM59651.1 - 0.041 14.0 0.2 0.078 13.1 0.2 1.4 1 0 0 1 1 1 0 FANCI solenoid 1 cap Calpain_III PF01067.22 KFM59653.1 - 4.9e-38 130.6 0.0 7.2e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 KFM59653.1 - 3.5e-06 26.3 0.4 4.9e-06 25.8 0.4 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease WASH-7_N PF14745.6 KFM59655.1 - 6e-222 738.2 5.8 6.9e-222 738.0 5.8 1.0 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 KFM59655.1 - 5.6e-29 101.3 0.3 5.6e-29 101.3 0.3 1.9 2 0 0 2 2 2 1 WASH complex subunit 7 Hemagglutinin PF00509.18 KFM59655.1 - 0.0048 15.4 0.9 0.12 10.8 0.1 2.4 3 0 0 3 3 3 2 Haemagglutinin DUF2018 PF09442.10 KFM59655.1 - 0.051 14.5 0.1 0.29 12.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) DDE_3 PF13358.6 KFM59656.1 - 1.6e-16 60.4 0.1 1.7e-15 57.1 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59656.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase IRS PF02174.17 KFM59658.1 - 3.6e-23 81.3 0.0 7e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFM59658.1 - 1.1e-13 51.6 0.1 3.5e-13 50.0 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFM59658.1 - 0.014 15.8 0.6 0.032 14.6 0.6 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.6 KFM59658.1 - 0.016 15.5 0.1 0.069 13.4 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 KFM59658.1 - 0.77 10.2 3.2 1.3 9.5 0.7 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain DDE_3 PF13358.6 KFM59659.1 - 2.7e-16 59.6 0.1 2.9e-15 56.3 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59659.1 - 1.3e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase Pkinase PF00069.25 KFM59660.1 - 1.4e-41 142.6 0.1 1.8e-41 142.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM59660.1 - 3.2e-25 88.9 0.0 4e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM59660.1 - 0.00082 18.8 0.1 0.0048 16.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFM59660.1 - 0.00096 19.1 0.2 0.0012 18.8 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM59660.1 - 0.0038 16.1 0.0 0.0067 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM59660.1 - 0.02 13.8 0.3 0.024 13.6 0.3 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFM59660.1 - 0.072 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFM59661.1 - 0.0017 17.8 0.2 0.0017 17.8 0.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Mitofilin PF09731.9 KFM59663.1 - 0.047 12.5 0.3 0.044 12.6 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4107 PF13389.6 KFM59663.1 - 0.13 12.4 0.7 0.16 12.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) TPR_MLP1_2 PF07926.12 KFM59664.1 - 0.0012 18.9 9.7 0.0012 18.9 9.7 4.6 3 2 1 4 4 4 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFM59664.1 - 0.0018 17.2 2.1 0.0018 17.2 2.1 3.4 2 1 1 3 3 3 1 Spc7 kinetochore protein Surfac_D-trimer PF09006.11 KFM59664.1 - 0.024 14.5 0.3 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation MbeD_MobD PF04899.12 KFM59664.1 - 0.048 13.8 0.8 0.048 13.8 0.8 4.2 4 0 0 4 4 4 0 MbeD/MobD like PRIMA1 PF16101.5 KFM59664.1 - 0.077 13.0 3.5 0.16 12.0 3.5 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FlaC_arch PF05377.11 KFM59664.1 - 0.28 11.6 0.1 0.28 11.6 0.1 4.7 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) IL11 PF07400.11 KFM59664.1 - 1.7 8.2 7.6 0.35 10.5 0.2 3.0 3 0 0 3 3 3 0 Interleukin 11 Myb_DNA-bind_3 PF12776.7 KFM59664.1 - 7.4 7.6 9.5 8.4 7.5 0.2 4.0 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain NPV_P10 PF05531.12 KFM59664.1 - 7.8 7.0 12.7 4.9 7.7 1.1 4.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Lipase PF00151.19 KFM59665.1 - 2.2e-84 283.6 0.0 2.5e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 Lipase DUF900 PF05990.12 KFM59665.1 - 0.006 16.1 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 KFM59665.1 - 0.013 16.1 0.1 0.02 15.5 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sigma70_r4_2 PF08281.12 KFM59665.1 - 0.098 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 LIDHydrolase PF10230.9 KFM59665.1 - 0.11 12.0 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 KFM59665.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UPF0227 PF05728.12 KFM59665.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Adaptin_binding PF10199.9 KFM59666.1 - 0.043 14.4 8.7 4.3 8.0 4.7 2.4 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 TetR_C_13 PF16925.5 KFM59666.1 - 0.062 13.2 4.4 0.12 12.3 0.5 2.9 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Baculo_PEP_N PF04512.12 KFM59666.1 - 0.37 11.1 1.8 14 6.0 0.3 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus TetR_C_24 PF17932.1 KFM59666.1 - 0.44 10.8 1.8 28 5.0 0.2 3.1 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain FAM184 PF15665.5 KFM59666.1 - 0.73 9.6 28.1 0.94 9.2 12.0 3.1 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B FadA PF09403.10 KFM59666.1 - 1.9 9.0 25.5 0.24 11.9 3.2 3.7 3 1 0 3 3 3 0 Adhesion protein FadA DUF948 PF06103.11 KFM59666.1 - 10 6.5 7.3 21 5.5 0.5 3.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Lipase PF00151.19 KFM59667.1 - 2.4e-86 290.1 0.0 2.7e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFM59667.1 - 2.5e-06 28.3 0.1 4.6e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KFM59667.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.20 KFM59667.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Lipase PF00151.19 KFM59669.1 - 9.8e-80 268.4 0.0 1.1e-79 268.2 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFM59669.1 - 6.3e-06 26.9 0.2 9e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM59669.1 - 9e-05 22.2 0.1 0.00052 19.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 KFM59669.1 - 0.0093 15.5 0.0 0.024 14.1 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 KFM59669.1 - 0.029 13.9 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 KFM59669.1 - 0.053 13.4 0.0 0.14 12.0 0.0 1.7 1 1 1 2 2 2 0 Serine hydrolase Hydrolase_4 PF12146.8 KFM59669.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KFM59669.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Lipase PF00151.19 KFM59671.1 - 1.1e-77 261.6 0.0 1.3e-77 261.3 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFM59671.1 - 2.3e-05 25.1 0.1 3.4e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM59671.1 - 0.0043 16.7 0.0 0.0071 16.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DDE_3 PF13358.6 KFM59672.1 - 0.0023 17.7 0.0 0.0024 17.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PPO1_DWL PF12142.8 KFM59672.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.4 1 1 0 1 1 1 0 Polyphenol oxidase middle domain RT_RNaseH_2 PF17919.1 KFM59673.1 - 2.4e-40 136.6 0.0 8.1e-40 134.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM59673.1 - 1.3e-36 125.0 0.1 8.4e-36 122.4 0.0 2.5 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM59673.1 - 4.7e-31 108.0 0.0 1e-30 106.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM59673.1 - 7.2e-22 77.8 0.0 2.6e-20 72.8 0.0 3.0 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM59673.1 - 2.4e-20 72.4 0.0 1.1e-19 70.3 0.1 2.2 2 0 0 2 2 1 1 Integrase zinc binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM59673.1 - 9.9e-14 51.4 4.9 9.9e-14 51.4 4.9 2.9 3 0 0 3 3 1 1 Transposase gag-asp_proteas PF13975.6 KFM59673.1 - 2.4e-12 47.2 0.0 6.9e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DDE_3 PF13358.6 KFM59673.1 - 1.9e-11 43.9 0.0 4.7e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Asp_protease_2 PF13650.6 KFM59673.1 - 2.9e-10 40.7 0.0 8.8e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Apolipoprotein PF01442.18 KFM59673.1 - 1.1e-08 35.2 18.6 1.1e-08 35.2 18.6 3.6 4 0 0 4 4 3 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM59673.1 - 3.5e-07 30.3 4.4 0.00025 21.1 0.1 3.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus HTH_32 PF13565.6 KFM59673.1 - 6.1e-06 26.8 3.0 6.1e-06 26.8 3.0 4.5 4 0 0 4 4 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59673.1 - 1.4e-05 25.2 0.4 0.0015 18.6 0.0 3.1 2 0 0 2 2 2 1 Helix-turn-helix domain zf-H2C2 PF09337.10 KFM59673.1 - 2.8e-05 24.2 0.0 0.00012 22.3 0.0 2.2 1 0 0 1 1 1 1 H2C2 zinc finger HTH_7 PF02796.15 KFM59673.1 - 0.00029 20.9 0.1 0.011 15.7 0.0 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Asp_protease PF09668.10 KFM59673.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease HTH_23 PF13384.6 KFM59673.1 - 0.0019 18.0 0.0 0.0019 18.0 0.0 3.8 5 0 0 5 5 3 1 Homeodomain-like domain HSBP1 PF06825.12 KFM59673.1 - 0.0037 17.1 17.2 5.6 6.9 0.0 6.0 5 0 0 5 5 5 0 Heat shock factor binding protein 1 MarR_2 PF12802.7 KFM59673.1 - 0.01 15.7 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 0 MarR family CENP-B_N PF04218.13 KFM59673.1 - 0.015 15.0 0.0 0.045 13.4 0.0 1.9 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 KFM59673.1 - 0.021 14.6 0.0 0.071 12.9 0.0 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF1640 PF07798.11 KFM59673.1 - 0.037 14.1 31.6 0.61 10.1 13.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) Peptidase_M75 PF09375.10 KFM59673.1 - 0.037 13.5 7.3 0.089 12.3 7.3 1.6 1 0 0 1 1 1 0 Imelysin DUF2884 PF11101.8 KFM59673.1 - 0.05 13.1 25.0 0.56 9.7 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) rve_3 PF13683.6 KFM59673.1 - 0.057 13.2 0.0 0.29 10.9 0.0 2.3 1 0 0 1 1 1 0 Integrase core domain HTH_38 PF13936.6 KFM59673.1 - 0.087 12.6 0.1 0.33 10.8 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain ApoO PF09769.9 KFM59673.1 - 0.18 11.8 11.1 1.3 9.0 2.6 3.6 1 1 1 2 2 2 0 Apolipoprotein O Phasin PF05597.11 KFM59673.1 - 0.37 10.8 38.0 0.27 11.2 7.4 4.8 4 1 1 5 5 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF842 PF05811.13 KFM59673.1 - 0.82 9.4 22.7 0.088 12.5 15.0 2.7 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF4407 PF14362.6 KFM59673.1 - 0.87 8.9 14.7 2.3 7.5 14.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gp58 PF07902.11 KFM59673.1 - 1.3 7.2 14.1 3 6.0 14.1 1.5 1 0 0 1 1 1 0 gp58-like protein SF-assemblin PF06705.11 KFM59673.1 - 4.4 6.6 33.6 15 4.8 31.8 2.6 2 1 0 2 2 2 0 SF-assemblin/beta giardin Peptidase_S64 PF08192.11 KFM59673.1 - 4.7 5.6 20.7 8.9 4.7 20.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 FliG_M PF14841.6 KFM59673.1 - 7 7.0 8.1 12 6.2 0.1 3.7 3 1 1 4 4 2 0 FliG middle domain DUF883 PF05957.13 KFM59673.1 - 9.1 7.0 27.6 2.4 8.8 3.5 5.4 4 1 2 6 6 5 0 Bacterial protein of unknown function (DUF883) DDE_3 PF13358.6 KFM59674.1 - 2e-16 60.1 0.0 3e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59674.1 - 1.3e-10 41.4 1.0 2.7e-10 40.3 1.0 1.6 1 0 0 1 1 1 1 Transposase Lipase PF00151.19 KFM59675.1 - 4.9e-21 75.4 2.4 3.5e-10 39.7 0.5 2.1 2 0 0 2 2 2 2 Lipase Lipase PF00151.19 KFM59677.1 - 3.8e-67 227.0 0.0 4.6e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFM59677.1 - 1.8e-07 32.0 0.0 2.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KFM59677.1 - 0.017 14.7 0.0 0.062 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF900 PF05990.12 KFM59677.1 - 0.02 14.4 0.0 0.027 14.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 KFM59677.1 - 0.021 14.7 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KFM59677.1 - 0.085 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 KFM59677.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 KFM59677.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_8 PF06259.12 KFM59677.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 KFM59677.1 - 0.15 11.6 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Jagunal PF07086.12 KFM59678.1 - 3.3e-55 187.0 4.4 4.2e-55 186.7 4.4 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis DUF3961 PF13106.6 KFM59678.1 - 1.1 8.9 5.0 3.5 7.4 5.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Arf PF00025.21 KFM59679.1 - 2.7e-46 157.2 0.1 3.2e-46 157.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFM59679.1 - 1.4e-17 63.8 0.0 1.6e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM59679.1 - 1.2e-15 57.7 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFM59679.1 - 4.3e-10 39.3 0.0 5.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFM59679.1 - 3.4e-08 33.1 0.2 2.6e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFM59679.1 - 4.4e-07 29.5 0.0 5.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFM59679.1 - 0.0001 22.3 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFM59679.1 - 0.012 15.4 0.0 0.66 9.7 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein VirE PF05272.11 KFM59679.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E GTP_EFTU PF00009.27 KFM59679.1 - 0.028 14.0 0.0 0.049 13.2 0.0 1.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFM59679.1 - 0.13 12.3 0.1 4.4 7.3 0.1 2.1 1 1 1 2 2 2 0 Dynamin family AIRS_C PF02769.22 KFM59680.1 - 9.4e-30 103.8 0.1 1.3e-29 103.3 0.1 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KFM59680.1 - 3.1e-09 37.4 0.5 9.3e-09 35.8 0.1 1.9 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain LamB_YcsF PF03746.16 KFM59680.1 - 0.084 12.5 0.1 11 5.6 0.1 2.3 2 0 0 2 2 2 0 LamB/YcsF family CBM_14 PF01607.24 KFM59681.1 - 6.3e-11 42.3 6.6 1.1e-10 41.5 6.6 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Ribosomal_L6e PF01159.19 KFM59683.1 - 7 7.2 11.0 40 4.8 9.1 3.0 2 0 0 2 2 2 0 Ribosomal protein L6e DDE_1 PF03184.19 KFM59684.1 - 1.1e-10 41.5 0.0 1.2e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 KFM59685.1 - 1.8e-54 184.9 0.0 5e-54 183.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM59685.1 - 3.1e-43 147.9 0.0 8.5e-43 146.5 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFM59685.1 - 9.5e-27 93.0 4.8 4.5e-24 84.5 2.0 2.8 2 0 0 2 2 2 2 Oxidative-stress-responsive kinase 1 C-terminal domain 7tm_1 PF00001.21 KFM59686.1 - 2.1e-16 60.1 9.8 2.7e-16 59.7 9.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM59686.1 - 0.00027 20.4 5.0 0.00041 19.8 5.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Spo7 PF03907.13 KFM59686.1 - 0.19 11.2 2.3 0.26 10.7 2.3 1.2 1 0 0 1 1 1 0 Spo7-like protein DUF5641 PF18701.1 KFM59687.1 - 2.5e-21 75.6 0.6 4.3e-21 74.9 0.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Syntaxin PF00804.25 KFM59687.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Syntaxin Myb_DNA-bind_2 PF08914.11 KFM59687.1 - 1.3 9.2 5.0 0.67 10.2 1.6 2.1 2 0 0 2 2 2 0 Rap1 Myb domain HTH_Tnp_Tc3_2 PF01498.18 KFM59688.1 - 3.4e-16 59.2 3.2 5e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59688.1 - 9.8e-14 51.3 0.0 1.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59688.1 - 5.8e-06 26.0 0.8 2.7e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM59688.1 - 1.4 9.6 14.8 0.11 13.1 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59689.1 - 2.5e-16 59.7 2.2 4.6e-16 58.8 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59689.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CH PF00307.31 KFM59690.1 - 2.7e-14 53.2 0.0 4.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain GAS2 PF02187.17 KFM59690.1 - 4.8e-07 29.8 0.0 3.5e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain DEAD PF00270.29 KFM59691.1 - 1.8e-48 164.6 0.6 5.1e-48 163.1 0.3 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM59691.1 - 2.4e-25 89.0 0.0 4.3e-24 85.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFM59691.1 - 1e-19 70.5 0.2 1.9e-19 69.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFM59691.1 - 2.3e-10 40.7 0.7 3.8e-10 40.0 0.1 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFM59691.1 - 0.0004 20.2 0.0 0.0099 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain SecA_DEAD PF07517.14 KFM59691.1 - 0.00073 18.9 1.0 0.0017 17.7 0.1 2.1 3 0 0 3 3 3 1 SecA DEAD-like domain DUF2075 PF09848.9 KFM59691.1 - 0.0062 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KFM59691.1 - 0.013 15.8 2.7 0.13 12.6 2.7 2.3 1 1 0 1 1 1 0 AAA domain zf-CHCC PF10276.9 KFM59692.1 - 1.3e-17 63.5 2.0 2.4e-17 62.7 2.0 1.4 1 0 0 1 1 1 1 Zinc-finger domain Ribosomal_L36 PF00444.18 KFM59693.1 - 2.2e-13 50.2 2.5 2.2e-13 50.2 2.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L36 Flavokinase PF01687.17 KFM59694.1 - 1.5e-31 109.0 0.0 1.8e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Lipase PF00151.19 KFM59695.1 - 1.4e-84 284.3 0.0 1.6e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFM59695.1 - 0.0077 16.9 1.3 0.019 15.6 0.8 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM59695.1 - 0.042 13.5 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KFM59695.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain HTH_Tnp_Tc3_2 PF01498.18 KFM59696.1 - 7.7e-17 61.3 2.3 4.2e-16 58.9 2.2 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59696.1 - 9e-14 51.4 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease muHD PF10291.9 KFM59697.1 - 2.5e-58 197.6 0.0 3.7e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FAST_1 PF06743.15 KFM59698.1 - 2.5e-07 30.5 2.9 7.3e-07 29.1 0.1 3.1 3 1 1 4 4 4 1 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFM59698.1 - 0.0016 18.5 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 RAP domain DDE_Tnp_1_7 PF13843.6 KFM59699.1 - 5.4e-55 187.1 1.8 6.8e-55 186.8 1.8 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM59699.1 - 0.00011 23.0 12.0 0.00025 21.8 12.0 1.7 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon DUF5383 PF17355.2 KFM59699.1 - 0.038 14.4 2.5 0.55 10.6 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Alk_phosphatase PF00245.20 KFM59700.1 - 1.4e-141 472.2 0.7 1.7e-141 472.0 0.7 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 KFM59700.1 - 0.002 17.6 0.8 0.013 14.9 0.8 2.2 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KFM59700.1 - 0.03 13.7 1.5 0.049 13.0 0.7 1.6 2 1 0 2 2 2 0 Metalloenzyme superfamily Band_7 PF01145.25 KFM59701.1 - 2.5e-11 43.9 0.0 2.8e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family Kelch_1 PF01344.25 KFM59703.1 - 7.3e-81 265.6 22.7 1.1e-17 63.3 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFM59703.1 - 4.3e-36 122.0 14.6 1.8e-08 34.3 0.1 6.6 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFM59703.1 - 1e-32 112.3 0.9 2.1e-32 111.3 0.3 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFM59703.1 - 9.4e-30 103.1 0.5 1.6e-29 102.3 0.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 KFM59703.1 - 4.6e-28 96.1 10.6 6.5e-06 25.9 0.1 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFM59703.1 - 4.6e-21 74.6 12.1 0.0024 18.1 0.1 5.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFM59703.1 - 1.6e-20 72.9 0.2 0.00063 19.7 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM59703.1 - 1.4e-10 40.9 8.6 0.13 12.2 0.0 5.6 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.6 KFM59703.1 - 0.011 16.2 6.7 2.9 8.5 0.0 4.8 5 0 0 5 5 5 0 PQQ-like domain DUF5582 PF17819.1 KFM59704.1 - 0.052 14.0 2.9 0.06 13.8 2.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5582) DDE_3 PF13358.6 KFM59705.1 - 1.3e-10 41.2 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease ArsC PF03960.15 KFM59706.1 - 0.25 11.4 0.2 0.25 11.4 0.2 1.8 2 0 0 2 2 2 0 ArsC family DUF1682 PF07946.14 KFM59706.1 - 0.66 9.1 11.5 0.76 8.9 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Lge1 PF11488.8 KFM59706.1 - 0.7 10.1 10.9 2.2 8.5 5.8 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 UPF0160 PF03690.13 KFM59707.1 - 1.4e-132 442.2 0.0 1.6e-132 442.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Mitoc_L55 PF09776.9 KFM59708.1 - 3.5e-29 100.9 0.4 4.1e-29 100.7 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 HTH_Tnp_Tc3_2 PF01498.18 KFM59709.1 - 9.7e-15 54.6 0.6 2.1e-14 53.5 0.6 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59709.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59709.1 - 5.8e-07 30.0 3.3 5.8e-07 30.0 3.3 2.8 3 0 0 3 3 3 1 Homeodomain-like domain MarR_2 PF12802.7 KFM59709.1 - 0.0016 18.3 0.2 0.089 12.7 0.0 2.6 2 0 0 2 2 2 1 MarR family HTH_3 PF01381.22 KFM59709.1 - 0.016 15.2 0.3 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM59709.1 - 0.033 14.1 0.8 0.28 11.2 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM59709.1 - 0.082 13.0 1.0 4 7.7 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain FUR PF01475.19 KFM59709.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family GATA PF00320.27 KFM59710.1 - 0.17 11.5 2.6 4.1 7.1 0.2 2.4 1 1 1 2 2 2 0 GATA zinc finger ZZ PF00569.17 KFM59711.1 - 0.15 11.9 4.1 7 6.6 2.6 2.5 2 0 0 2 2 2 0 Zinc finger, ZZ type NHL PF01436.21 KFM59712.1 - 1e-34 116.8 9.3 1.3e-10 40.8 0.1 6.2 6 0 0 6 6 6 5 NHL repeat DUF5128 PF17170.4 KFM59712.1 - 2.4e-10 40.1 9.2 5.6e-08 32.3 0.3 3.6 3 1 1 4 4 4 2 6-bladed beta-propeller SGL PF08450.12 KFM59712.1 - 6.4e-08 32.5 0.2 0.031 13.8 0.0 3.3 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region zf-RING_UBOX PF13445.6 KFM59712.1 - 0.00023 21.1 12.7 0.00023 21.1 12.7 3.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM59712.1 - 0.00066 19.5 13.9 0.00066 19.5 13.9 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF3583 PF12126.8 KFM59712.1 - 0.002 17.6 0.5 0.0032 17.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-B_box PF00643.24 KFM59712.1 - 0.0082 16.3 8.1 0.0082 16.3 8.1 4.2 3 1 0 3 3 3 2 B-box zinc finger CHU_C PF13585.6 KFM59712.1 - 0.0082 16.2 1.4 5.8 7.0 0.0 3.8 4 0 0 4 4 4 1 C-terminal domain of CHU protein family zf-C3HC4_4 PF15227.6 KFM59712.1 - 0.011 15.9 11.1 0.011 15.9 11.1 3.5 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING STAT_alpha PF01017.20 KFM59712.1 - 1.3 8.8 6.0 1.6 8.6 4.3 1.8 2 0 0 2 2 2 0 STAT protein, all-alpha domain zf-H2C2_2 PF13465.6 KFM59713.1 - 1.5e-65 214.9 70.9 4.9e-10 39.4 1.1 11.1 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59713.1 - 1e-46 154.8 81.4 2.3e-05 24.6 1.9 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59713.1 - 4.7e-36 120.3 77.9 0.00082 20.0 0.5 10.2 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM59713.1 - 6.7e-29 99.4 79.1 0.00091 19.5 1.3 10.2 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM59713.1 - 5.9e-15 55.1 53.1 0.018 15.3 0.8 10.3 10 0 0 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM59713.1 - 6.8e-15 54.5 71.8 0.00024 20.8 1.7 9.6 10 0 0 10 10 10 7 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM59713.1 - 1.8e-13 50.0 48.9 0.07 12.9 0.3 10.5 11 0 0 11 11 11 6 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM59713.1 - 2.1e-13 49.9 68.7 0.0098 15.9 1.4 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM59713.1 - 7e-11 42.0 29.3 0.33 11.1 0.2 9.3 7 3 2 9 9 9 3 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM59713.1 - 2e-07 30.7 47.1 0.48 10.3 0.2 9.9 2 2 8 10 10 10 3 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM59713.1 - 2.7e-06 27.5 15.1 0.79 10.0 0.1 6.9 1 1 6 7 7 7 2 BolA-like protein zf-DBF PF07535.12 KFM59713.1 - 3.2e-05 24.0 35.6 8.7 6.5 0.2 9.9 10 0 0 10 10 10 0 DBF zinc finger FYVE PF01363.21 KFM59713.1 - 0.0001 22.4 49.2 0.015 15.4 5.7 5.1 3 2 0 3 3 3 2 FYVE zinc finger DUF2256 PF10013.9 KFM59713.1 - 0.00015 21.8 34.5 2.7 8.2 0.1 9.6 10 0 0 10 10 10 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFM59713.1 - 0.00022 21.1 38.6 2.2 8.3 0.1 9.8 10 0 0 10 10 10 1 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM59713.1 - 0.00041 20.4 43.7 0.44 10.7 6.0 4.8 1 1 3 4 4 4 2 Putative ribonucleoprotein zinc-finger pf C4 type GAGA PF09237.11 KFM59713.1 - 0.00097 18.9 15.9 6 6.7 0.0 7.1 2 2 6 8 8 8 2 GAGA factor Complex1_49kDa PF00346.19 KFM59713.1 - 0.0077 15.4 3.5 0.048 12.7 0.4 2.4 1 1 2 3 3 3 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-C2H2_2 PF12756.7 KFM59713.1 - 0.0091 16.3 74.5 1 9.8 2.2 9.8 1 1 8 9 9 9 2 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM59713.1 - 0.014 15.4 28.6 0.21 11.6 1.0 6.4 3 3 4 7 7 7 0 Adenylate kinase, active site lid PH_3 PF14593.6 KFM59713.1 - 0.015 15.4 2.7 4.7 7.4 0.0 3.9 1 1 1 3 3 3 0 PH domain Tox-HNH-HHH PF15637.6 KFM59713.1 - 0.017 15.2 5.7 14 5.9 0.1 4.1 1 1 2 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Dof PF02701.15 KFM59713.1 - 0.027 14.6 28.0 15 5.8 0.3 8.3 2 2 3 7 7 7 0 Dof domain, zinc finger Peptidase_M15_2 PF05951.13 KFM59713.1 - 0.041 13.6 0.5 5.5 6.6 0.0 3.7 1 1 3 5 5 5 0 Bacterial protein of unknown function (DUF882) zinc_ribbon_15 PF17032.5 KFM59713.1 - 0.061 14.1 43.0 7.1 7.5 2.3 5.5 1 1 6 7 7 7 0 zinc-ribbon family YyzF PF14116.6 KFM59713.1 - 0.95 9.5 36.6 18 5.4 0.2 9.4 10 0 0 10 10 10 0 YyzF-like protein Cas_CXXC_CXXC PF09706.10 KFM59713.1 - 1.8 8.9 36.4 2.4 8.5 0.1 9.0 1 1 8 9 9 8 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-MYST PF17772.1 KFM59713.1 - 5 6.8 46.7 4 7.1 0.3 9.6 3 3 7 10 10 10 0 MYST family zinc finger domain F-box-like_2 PF13013.6 KFM59713.1 - 6.8 6.7 7.6 62 3.6 0.7 3.5 1 1 2 3 3 3 0 F-box-like domain DUF1636 PF07845.11 KFM59714.1 - 0.00046 20.6 0.4 0.13 12.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1636) zf-H2C2_2 PF13465.6 KFM59715.1 - 8.8e-75 244.1 78.6 4.6e-09 36.3 0.9 11.6 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59715.1 - 2.7e-53 175.5 89.4 2.8e-06 27.5 3.0 11.1 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59715.1 - 5.1e-37 123.3 81.9 0.00036 21.1 1.9 11.0 11 0 0 11 11 11 10 C2H2-type zinc finger zf-met PF12874.7 KFM59715.1 - 3.9e-26 90.6 76.8 0.0021 18.4 1.1 11.3 11 0 0 11 11 11 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM59715.1 - 1.4e-15 56.8 75.4 0.047 13.7 0.6 11.3 11 0 0 11 11 11 8 C2H2-type zinc finger GAGA PF09237.11 KFM59715.1 - 2.2e-15 56.2 23.3 0.0043 16.8 0.2 8.1 3 3 6 9 9 9 6 GAGA factor zf-C2H2_jaz PF12171.8 KFM59715.1 - 1.4e-14 53.9 63.8 0.18 12.2 0.7 11.4 11 0 0 11 11 11 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM59715.1 - 1.9e-12 46.7 60.0 0.0011 18.6 0.9 10.6 10 0 0 10 10 10 5 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 KFM59715.1 - 1.4e-10 40.9 42.2 0.41 10.5 0.1 10.0 3 3 7 10 10 10 5 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM59715.1 - 2.4e-08 34.2 21.2 0.44 10.9 0.1 6.4 2 2 4 6 6 6 3 BolA-like protein zf-RRPl_C4 PF17026.5 KFM59715.1 - 4e-05 23.7 40.1 0.016 15.3 5.6 5.0 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-MYST PF17772.1 KFM59715.1 - 0.00029 20.4 44.9 0.5 10.0 0.2 9.6 5 2 5 10 10 10 3 MYST family zinc finger domain DUF2256 PF10013.9 KFM59715.1 - 0.00071 19.6 32.9 5.5 7.2 0.2 9.8 10 0 0 10 10 10 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KFM59715.1 - 0.0028 17.9 70.5 2.3 8.6 1.6 9.9 1 1 8 9 9 9 2 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.15 KFM59715.1 - 0.003 17.6 37.1 0.2 11.7 0.2 9.4 8 2 2 10 10 10 2 Sec23/Sec24 zinc finger Tox-HNH-HHH PF15637.6 KFM59715.1 - 0.0033 17.6 7.0 0.53 10.5 0.1 3.9 3 1 1 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf_UBZ PF18439.1 KFM59715.1 - 0.0075 15.8 42.2 3.6 7.3 0.2 10.0 10 0 0 10 10 10 2 Ubiquitin-Binding Zinc Finger RsfS PF02410.15 KFM59715.1 - 0.0089 16.4 2.2 6.8 7.2 2.1 3.5 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation zf-DBF PF07535.12 KFM59715.1 - 0.012 15.7 41.6 9.9 6.4 0.1 10.1 10 0 0 10 10 10 0 DBF zinc finger ADK_lid PF05191.14 KFM59715.1 - 0.023 14.7 40.0 2.8 8.0 0.2 7.0 2 2 5 7 7 7 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM59715.1 - 0.052 14.3 42.0 1.6 9.5 1.5 5.5 1 1 4 7 7 7 0 zinc-ribbon family AMP_N PF05195.16 KFM59715.1 - 0.064 13.0 0.0 85 2.9 0.0 4.1 4 1 0 4 4 4 0 Aminopeptidase P, N-terminal domain zf-C2HC_2 PF13913.6 KFM59715.1 - 0.13 12.2 50.1 1.3 9.0 0.1 10.0 11 0 0 11 11 10 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFM59715.1 - 0.23 11.6 44.2 8.7 6.5 2.0 9.3 2 2 5 7 7 7 0 KIAA1045 RING finger YyzF PF14116.6 KFM59715.1 - 3.8 7.6 30.7 33 4.6 0.1 9.1 10 0 0 10 10 10 0 YyzF-like protein zf-C2H2_4 PF13894.6 KFM59716.1 - 7.4 7.7 7.3 41 5.4 0.1 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM59717.1 - 7.1e-92 298.1 94.2 1e-08 35.2 0.2 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59717.1 - 3.7e-54 178.3 111.0 2.2e-05 24.6 0.3 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-met PF12874.7 KFM59717.1 - 3.4e-43 144.8 99.7 3e-05 24.2 2.2 11.2 11 0 0 11 11 11 11 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM59717.1 - 4.7e-35 117.2 100.7 0.00034 21.2 0.3 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM59717.1 - 7.1e-18 64.4 41.1 0.067 13.2 0.1 11.8 3 3 9 12 12 12 8 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 KFM59717.1 - 1.2e-17 63.4 79.5 0.013 15.5 3.3 11.5 11 0 0 11 11 11 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM59717.1 - 2e-17 63.0 72.5 0.087 13.1 0.7 11.4 11 0 0 11 11 11 11 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM59717.1 - 4.9e-08 32.7 52.1 1.8 8.5 0.2 11.4 11 0 0 11 11 11 3 zinc-finger of a C2HC-type BolA PF01722.18 KFM59717.1 - 4.6e-07 30.0 23.7 0.24 11.7 0.1 7.3 1 1 6 7 7 7 2 BolA-like protein zf-RRPl_C4 PF17026.5 KFM59717.1 - 1e-06 28.8 48.6 0.047 13.8 7.5 4.8 1 1 4 5 5 5 5 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM59717.1 - 1.5e-06 28.2 66.0 3 8.0 0.9 11.2 11 0 0 11 11 11 2 DBF zinc finger FAM83 PF07894.12 KFM59717.1 - 7.4e-05 22.4 9.0 0.0024 17.5 0.6 3.3 1 1 3 4 4 4 2 FAM83 A-H Zf_RING PF16744.5 KFM59717.1 - 0.00027 21.0 55.1 7.6 6.7 0.3 10.8 1 1 8 10 10 10 0 KIAA1045 RING finger DUF2256 PF10013.9 KFM59717.1 - 0.0049 17.0 47.0 21 5.3 0.1 11.0 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 KFM59717.1 - 0.014 15.2 61.2 6.3 6.7 0.3 10.9 1 1 10 11 11 11 0 C2H2 type zinc-finger (1 copy) IGPD PF00475.18 KFM59717.1 - 0.018 15.3 20.4 4.5 7.6 0.2 6.3 1 1 4 7 7 7 0 Imidazoleglycerol-phosphate dehydratase Zn-ribbon_8 PF09723.10 KFM59717.1 - 0.029 14.5 43.1 1.9 8.7 1.5 7.0 3 2 4 7 7 7 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM59717.1 - 0.041 14.6 50.3 2.7 8.8 2.1 6.0 1 1 5 7 7 7 0 zinc-ribbon family A_deaminase PF00962.22 KFM59717.1 - 0.041 13.2 25.8 1.9 7.7 0.7 6.2 1 1 4 6 6 6 0 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KFM59717.1 - 0.065 12.5 26.3 7.4 5.8 0.2 6.3 1 1 4 6 6 6 0 Amidohydrolase family C1_1 PF00130.22 KFM59717.1 - 0.13 12.2 68.5 6.2 6.8 1.0 9.5 1 1 8 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM59717.1 - 0.41 10.5 29.3 3.6 7.5 0.0 8.4 1 1 10 11 11 11 0 GAGA factor zinc-ribbons_6 PF07191.12 KFM59717.1 - 0.47 10.5 54.2 12 6.0 3.2 9.1 1 1 7 8 8 8 0 zinc-ribbons zf-C2H2_11 PF16622.5 KFM59717.1 - 1 9.2 0.0 1 9.2 0.0 10.6 11 0 0 11 11 11 0 zinc-finger C2H2-type zf-RING_UBOX PF13445.6 KFM59717.1 - 1.4 9.0 24.1 2.1e+02 2.0 0.1 9.5 11 0 0 11 11 11 0 RING-type zinc-finger zf-CCHC_6 PF15288.6 KFM59718.1 - 0.00011 22.0 0.3 0.00024 20.8 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle DnaJ PF00226.31 KFM59719.1 - 4.7e-29 100.3 4.4 6.5e-29 99.9 4.4 1.2 1 0 0 1 1 1 1 DnaJ domain SET PF00856.28 KFM59720.1 - 1.4e-17 64.6 0.7 1.2e-16 61.6 0.7 2.1 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KFM59720.1 - 5.2e-13 49.6 12.2 5.2e-13 49.6 12.2 1.9 2 0 0 2 2 2 1 Pre-SET motif HTH_Tnp_Tc3_2 PF01498.18 KFM59722.1 - 1.5e-15 57.2 6.5 2.7e-15 56.4 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59722.1 - 1.6e-15 57.2 0.1 1.3e-14 54.2 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59722.1 - 0.0013 19.3 1.5 0.0013 19.3 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59724.1 - 1.2e-06 28.7 1.1 1.6e-06 28.3 1.1 1.1 1 0 0 1 1 1 1 Transposase Suf PF05843.14 KFM59725.1 - 3.6e-08 33.8 2.8 3.6e-08 33.8 2.8 1.6 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Globin PF00042.22 KFM59725.1 - 0.00081 19.9 2.4 0.44 11.1 0.2 2.7 3 0 0 3 3 3 2 Globin NRDE-2 PF08424.10 KFM59725.1 - 0.0018 17.4 0.1 0.0018 17.4 0.1 3.3 2 1 2 4 4 4 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KFM59725.1 - 0.0032 18.2 0.1 0.71 10.8 0.0 3.7 2 2 2 4 4 4 1 Tetratricopeptide repeat Rep_Org_C PF06926.11 KFM59725.1 - 0.014 15.7 1.1 0.062 13.6 0.1 2.5 3 0 0 3 3 3 0 Putative replisome organiser protein C-terminus Pkinase_Tyr PF07714.17 KFM59726.1 - 9.7e-60 202.0 0.0 1.4e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM59726.1 - 3.6e-54 183.9 0.0 6.2e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFM59726.1 - 0.0078 16.2 0.0 0.025 14.5 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Gal_Lectin PF02140.18 KFM59728.1 - 9.3e-21 74.1 1.3 1.4e-20 73.5 1.3 1.3 1 0 0 1 1 1 1 Galactose binding lectin domain Atrophin-1 PF03154.15 KFM59729.1 - 1.4e-31 109.7 68.4 2.6e-19 69.1 21.2 4.4 3 2 2 5 5 5 2 Atrophin-1 family GATA PF00320.27 KFM59729.1 - 1.6e-05 24.4 4.3 3.5e-05 23.3 4.3 1.6 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.31 KFM59729.1 - 0.00023 21.3 0.8 0.00061 19.9 0.8 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFM59729.1 - 0.0022 17.8 0.2 0.011 15.6 0.2 2.2 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KFM59729.1 - 0.09 13.0 0.2 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFM59730.1 - 1.7e-07 31.5 0.0 2.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-CCCH PF00642.24 KFM59731.1 - 1.3e-09 37.8 3.2 2.5e-09 36.8 3.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 KFM59731.1 - 1.8e-07 30.9 9.3 3.6e-07 29.9 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM59731.1 - 5.7e-07 29.3 7.1 1e-06 28.5 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM59731.1 - 4.9e-06 26.4 11.3 8.7e-06 25.6 11.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFM59731.1 - 1.8e-05 24.5 11.5 3.9e-05 23.4 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM59731.1 - 3e-05 24.2 8.9 6.5e-05 23.2 8.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 KFM59731.1 - 3.7e-05 23.6 5.0 9e-05 22.4 5.0 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-RING_UBOX PF13445.6 KFM59731.1 - 5.5e-05 23.1 9.7 0.00012 22.1 9.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM59731.1 - 0.00051 20.1 9.5 0.00051 20.1 9.5 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFM59731.1 - 0.0012 18.6 3.2 0.0025 17.6 3.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFM59731.1 - 0.0018 18.4 5.0 0.0018 18.4 5.0 2.2 2 1 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KFM59731.1 - 0.0038 17.1 6.8 0.0071 16.2 6.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 KFM59731.1 - 0.005 16.6 3.2 0.005 16.6 3.2 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFM59731.1 - 0.033 14.7 3.1 0.082 13.4 3.1 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-RING_6 PF14835.6 KFM59731.1 - 0.13 12.1 4.1 0.28 11.1 4.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 KFM59731.1 - 0.27 10.9 5.5 0.58 9.9 5.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_11 PF17123.5 KFM59731.1 - 2 8.2 6.2 5 7.0 6.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KFM59731.1 - 2.1 8.7 8.2 39 4.6 8.2 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RanBP PF00641.18 KFM59731.1 - 4.2 6.8 13.0 0.053 12.8 3.3 2.4 3 0 0 3 3 2 0 Zn-finger in Ran binding protein and others C1_2 PF03107.16 KFM59731.1 - 8.9 6.7 10.7 91 3.5 0.1 2.7 1 1 1 2 2 2 0 C1 domain Npa1 PF11707.8 KFM59732.1 - 2.2e-12 47.0 0.4 2.4e-12 46.9 0.4 1.0 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Npa1 PF11707.8 KFM59733.1 - 7.8e-09 35.3 0.0 9.1e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Haspin_kinase PF12330.8 KFM59735.1 - 2.7e-25 89.1 0.9 3.2e-25 88.9 0.9 1.1 1 0 0 1 1 1 1 Haspin like kinase domain HTH_Tnp_Tc3_2 PF01498.18 KFM59736.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59736.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SSF PF00474.17 KFM59739.1 - 5.7e-08 32.0 1.3 6.7e-08 31.8 1.3 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2070 PF09843.9 KFM59739.1 - 0.15 10.4 0.9 0.18 10.1 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-CCCH_6 PF18585.1 KFM59739.1 - 0.42 10.5 3.0 0.28 11.1 0.9 1.8 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 SSF PF00474.17 KFM59741.1 - 0.052 12.4 0.1 0.088 11.7 0.1 1.4 1 0 0 1 1 1 0 Sodium:solute symporter family SSF PF00474.17 KFM59742.1 - 1.1e-33 116.7 21.3 1.4e-33 116.4 21.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Pox_A14 PF05767.12 KFM59742.1 - 0.39 10.9 10.1 4.2 7.6 1.1 3.7 3 1 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF4149 PF13664.6 KFM59742.1 - 9.4 6.6 14.4 1.4 9.3 6.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) IP_trans PF02121.18 KFM59743.1 - 5.8e-16 58.8 0.4 5.9e-16 58.8 0.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein FOXO-TAD PF16676.5 KFM59744.1 - 2.6e-16 59.7 0.9 4.9e-16 58.8 0.9 1.5 1 0 0 1 1 1 1 Transactivation domain of FOXO protein family TFIIA PF03153.13 KFM59744.1 - 3.9 7.4 18.7 0.87 9.5 15.6 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HTH_Tnp_Tc3_2 PF01498.18 KFM59745.1 - 4.6e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59745.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59745.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59745.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59745.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM59746.1 - 3.8e-16 59.2 0.1 4.2e-15 55.8 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59746.1 - 7.5e-16 58.2 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM59746.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59746.1 - 0.0026 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59746.1 - 0.015 15.4 0.1 0.065 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM59746.1 - 0.035 14.1 0.4 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Pex14_N PF04695.13 KFM59747.1 - 3.8e-14 53.6 1.1 3.8e-14 53.6 1.1 2.9 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF16 PF01519.16 KFM59747.1 - 0.003 18.0 0.3 0.0063 17.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF16 XhlA PF10779.9 KFM59747.1 - 0.027 14.7 1.5 0.083 13.1 1.5 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Prominin PF05478.11 KFM59747.1 - 0.031 12.2 0.1 0.039 11.9 0.1 1.1 1 0 0 1 1 1 0 Prominin PspA_IM30 PF04012.12 KFM59747.1 - 0.04 13.5 0.5 0.089 12.4 0.5 1.5 1 0 0 1 1 1 0 PspA/IM30 family SlyX PF04102.12 KFM59747.1 - 0.044 14.4 0.4 0.13 12.9 0.4 1.8 1 0 0 1 1 1 0 SlyX COG2 PF06148.11 KFM59747.1 - 0.059 13.5 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AATF-Che1 PF13339.6 KFM59747.1 - 0.068 13.9 0.4 0.14 12.9 0.4 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor YvrJ PF12841.7 KFM59747.1 - 0.077 12.5 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 YvrJ protein family AA_permease_2 PF13520.6 KFM59748.1 - 2.2e-52 178.3 30.0 2.2e-52 178.3 30.0 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFM59748.1 - 4.1e-34 118.0 28.6 4.1e-34 118.0 28.6 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFM59748.1 - 1.7e-19 69.6 8.6 1.7e-19 69.6 8.6 4.6 5 0 0 5 5 5 1 C-terminus of AA_permease DDE_3 PF13358.6 KFM59750.1 - 0.00045 20.0 0.2 0.00049 19.9 0.2 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Frag1 PF10277.9 KFM59751.1 - 1.5e-27 96.5 21.6 1.8e-27 96.3 21.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family RT_RNaseH_2 PF17919.1 KFM59752.1 - 1e-30 105.7 0.0 4.9e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM59752.1 - 2.6e-29 101.6 0.0 1.4e-28 99.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM59752.1 - 2.1e-28 99.4 0.1 5.7e-28 98.0 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM59752.1 - 2e-18 66.7 0.0 3.6e-17 62.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM59752.1 - 2.2e-16 59.7 0.0 7.8e-16 57.9 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Arc_C PF18162.1 KFM59752.1 - 3.8e-05 23.5 1.7 0.00013 21.7 0.4 2.7 3 0 0 3 3 3 1 Arc C-lobe zf-H2C2 PF09337.10 KFM59752.1 - 0.0016 18.6 0.0 0.004 17.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM59752.1 - 0.021 15.1 2.8 0.23 11.7 0.0 3.8 3 0 0 3 3 3 0 Retrotransposon gag protein Frag1 PF10277.9 KFM59753.1 - 2.6e-35 121.9 11.5 3.1e-35 121.7 11.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1079 PF06435.11 KFM59753.1 - 0.19 11.9 0.1 0.4 10.9 0.1 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) Amastin PF07344.11 KFM59753.1 - 0.21 11.4 6.5 0.042 13.7 1.9 2.1 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF3493 PF11998.8 KFM59753.1 - 0.37 11.0 2.5 0.36 11.0 0.9 1.8 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Frag1 PF10277.9 KFM59754.1 - 1.6e-30 106.3 14.3 2e-30 106.0 14.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family PhoLip_ATPase_C PF16212.5 KFM59754.1 - 8.2 6.1 18.8 9.7 5.9 16.9 2.0 1 1 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal Frag1 PF10277.9 KFM59755.1 - 3.2e-11 43.2 16.0 5.4e-11 42.4 16.0 1.3 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family CBS PF00571.28 KFM59756.1 - 0.0011 19.4 0.1 1.7 9.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain Herpes_BTRF1 PF04682.12 KFM59756.1 - 0.15 11.4 0.2 0.29 10.4 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region DUF4726 PF15855.5 KFM59756.1 - 0.15 12.3 0.6 2.6 8.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) Voltage_CLC PF00654.20 KFM59757.1 - 7.3e-24 84.7 6.0 7.8e-24 84.6 6.0 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel FAM199X PF15814.5 KFM59758.1 - 0.034 13.2 1.2 0.038 13.1 1.2 1.0 1 0 0 1 1 1 0 Protein family FAM199X PrmC_N PF17827.1 KFM59758.1 - 0.099 13.2 1.6 0.21 12.2 1.6 1.6 1 1 0 1 1 1 0 PrmC N-terminal domain TRAP-gamma PF07074.12 KFM59760.1 - 0.039 13.5 0.7 0.042 13.4 0.7 1.0 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) PIF3 PF05006.12 KFM59761.1 - 0.013 15.6 0.2 0.013 15.6 0.2 1.1 1 0 0 1 1 1 0 Per os infectivity factor 3 SpmSyn_N PF17950.1 KFM59763.1 - 0.082 13.1 0.3 0.21 11.8 0.1 1.8 1 1 1 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal DUF2757 PF10955.8 KFM59763.1 - 0.12 12.7 1.8 0.21 11.9 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) HTH_Tnp_Tc3_2 PF01498.18 KFM59765.1 - 6.4e-16 58.4 6.5 1.5e-15 57.2 6.5 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59765.1 - 6.7e-14 51.9 0.0 7.8e-13 48.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM59765.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59765.1 - 0.0023 17.7 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59765.1 - 0.016 15.3 0.1 0.065 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM59765.1 - 0.035 14.1 0.4 0.035 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix tRNA-synt_1b PF00579.25 KFM59766.1 - 0.00035 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1b PF00579.25 KFM59767.1 - 6.2e-13 48.7 0.0 6.6e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1b PF00579.25 KFM59768.1 - 0.029 13.7 0.0 0.029 13.7 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) CENP-B_N PF04218.13 KFM59770.1 - 0.00041 19.9 0.1 0.00056 19.5 0.1 1.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFM59770.1 - 0.018 14.8 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Pur_DNA_glyco PF02245.16 KFM59771.1 - 0.015 14.8 0.0 0.018 14.5 0.0 1.0 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) Radical_SAM_C PF16199.5 KFM59772.1 - 1e-32 112.0 0.0 2.4e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KFM59772.1 - 3e-23 83.0 2.1 2.7e-22 79.9 0.4 3.0 3 1 1 4 4 4 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KFM59772.1 - 5e-13 49.3 0.1 9.5e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM59772.1 - 1.7e-05 24.8 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM59772.1 - 0.0025 18.2 0.0 0.0055 17.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BC10 PF06726.12 KFM59773.1 - 5.6e-26 90.5 8.2 7.4e-26 90.2 8.2 1.1 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 7tm_3 PF00003.22 KFM59774.1 - 3.1e-12 46.7 8.1 3.7e-12 46.5 8.1 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2070 PF09843.9 KFM59774.1 - 2 6.6 4.5 2.2 6.5 4.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pkinase_Tyr PF07714.17 KFM59775.1 - 7.1e-88 294.2 0.0 8e-88 294.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM59775.1 - 2.4e-43 148.4 0.0 2.9e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KFM59775.1 - 1.7e-05 24.0 0.0 2.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM59775.1 - 0.002 18.1 0.1 0.057 13.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family B2 PF11473.8 KFM59775.1 - 0.0041 16.9 0.1 0.17 11.7 0.1 2.2 2 0 0 2 2 2 1 RNA binding protein B2 Kdo PF06293.14 KFM59775.1 - 0.0083 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NTF2 PF02136.20 KFM59776.1 - 5.4e-24 85.1 0.0 6e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KFM59776.1 - 0.00066 19.7 0.1 0.00075 19.5 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF4518 PF15008.6 KFM59776.1 - 0.04 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Nucleoside_tran PF01733.18 KFM59777.1 - 3.2e-12 46.4 1.8 3.7e-12 46.2 1.8 1.1 1 0 0 1 1 1 1 Nucleoside transporter Histone PF00125.24 KFM59779.1 - 1.6e-18 67.3 0.0 4.9e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFM59779.1 - 9.5e-13 47.6 0.6 2.1e-12 46.6 0.6 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A DDE_Tnp_1_7 PF13843.6 KFM59779.1 - 0.004 16.5 0.1 0.0054 16.1 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 CBFD_NFYB_HMF PF00808.23 KFM59779.1 - 0.05 13.9 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Tim17 PF02466.19 KFM59780.1 - 2e-08 34.6 1.4 2.6e-08 34.2 1.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HTH_IclR PF09339.10 KFM59781.1 - 0.00027 20.7 0.0 0.0005 19.8 0.0 1.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KFM59781.1 - 0.0028 17.4 1.0 0.003 17.3 0.1 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_35 PF13693.6 KFM59781.1 - 0.0078 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 KFM59781.1 - 0.13 12.6 3.3 0.29 11.5 1.3 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain DUF2046 PF09755.9 KFM59782.1 - 3.6e-146 486.2 52.1 5.2e-146 485.6 52.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF3828 PF12883.7 KFM59782.1 - 0.34 11.3 6.5 0.2 12.0 2.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3828) WD40 PF00400.32 KFM59783.1 - 1.2e-15 57.6 12.6 3.3e-05 24.5 0.1 7.0 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM59783.1 - 1.8e-11 44.2 0.0 0.0021 18.3 0.0 5.7 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFM59783.1 - 4.7e-08 33.3 3.5 0.32 11.6 0.1 5.1 5 0 0 5 5 5 2 PQQ-like domain WD40_like PF17005.5 KFM59783.1 - 3.3e-07 30.0 0.3 0.0045 16.4 0.1 2.4 1 1 1 2 2 2 2 WD40-like domain PQQ PF01011.21 KFM59783.1 - 0.00011 21.9 0.0 3 7.9 0.0 4.4 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.6 KFM59783.1 - 0.00089 18.9 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain Itfg2 PF15907.5 KFM59783.1 - 0.0016 17.6 0.3 0.33 10.0 0.1 2.4 2 0 0 2 2 2 2 Integrin-alpha FG-GAP repeat-containing protein 2 Ge1_WD40 PF16529.5 KFM59783.1 - 0.0033 16.4 0.6 2.8 6.8 0.0 3.7 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 KFM59783.1 - 0.0045 16.6 0.2 0.023 14.3 0.1 1.9 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 Peptidase_S9_N PF02897.15 KFM59783.1 - 0.01 14.7 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF1513 PF07433.11 KFM59783.1 - 0.021 13.9 0.0 0.8 8.7 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) eIF2A PF08662.11 KFM59783.1 - 0.13 12.1 0.2 0.87 9.4 0.0 2.1 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Utp8 PF10395.9 KFM59783.1 - 0.15 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Utp8 family Peptidase_A17 PF05380.13 KFM59784.1 - 3.7e-51 173.3 0.1 8.2e-51 172.2 0.1 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF5641 PF18701.1 KFM59784.1 - 1.1e-22 80.0 0.3 2.7e-22 78.7 0.3 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1758 PF05585.12 KFM59784.1 - 4.4e-13 49.3 0.2 1e-12 48.1 0.2 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 KFM59784.1 - 2.8e-10 40.2 2.7 2.8e-10 40.2 2.7 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KFM59784.1 - 4.3e-09 36.6 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KFM59784.1 - 0.00098 19.3 0.9 0.0029 17.8 0.9 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 KFM59784.1 - 0.0089 16.7 0.0 0.038 14.6 0.0 2.1 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM59784.1 - 0.01 16.4 0.0 0.064 13.8 0.0 2.2 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease GF_recep_IV PF14843.6 KFM59784.1 - 0.26 11.1 13.0 0.094 12.5 8.8 2.2 2 0 0 2 2 2 0 Growth factor receptor domain IV KIAA1430 PF13879.6 KFM59785.1 - 6.8e-10 39.6 12.2 6.8e-10 39.6 12.2 2.2 2 0 0 2 2 2 1 KIAA1430 homologue NDUF_B7 PF05676.13 KFM59786.1 - 0.025 14.3 0.2 0.033 13.9 0.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) zf-CCHC PF00098.23 KFM59786.1 - 0.037 14.1 0.5 0.037 14.1 0.5 1.6 2 0 0 2 2 2 0 Zinc knuckle DDE_3 PF13358.6 KFM59787.1 - 2.1e-05 24.3 0.0 2.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease tRNA-synt_1e PF01406.19 KFM59789.1 - 7.4e-107 357.2 0.0 9.9e-107 356.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFM59789.1 - 5.6e-07 28.7 0.1 0.0013 17.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFM59789.1 - 0.00033 19.1 0.0 0.0017 16.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 KFM59789.1 - 0.0038 16.2 0.1 0.019 13.9 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain HTH_Tnp_Tc3_2 PF01498.18 KFM59790.1 - 5.1e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59790.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59790.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59790.1 - 0.0027 17.4 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59790.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ig_3 PF13927.6 KFM59791.1 - 5e-05 23.8 0.0 7.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM59791.1 - 0.0014 18.6 0.0 0.0057 16.7 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM59791.1 - 0.0031 17.8 0.0 0.0055 17.0 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM59791.1 - 0.018 15.2 0.0 0.047 13.9 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 KFM59791.1 - 0.044 13.9 0.0 0.092 12.8 0.0 1.5 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain G_glu_transpept PF01019.21 KFM59792.1 - 7.2e-163 543.0 0.0 8.1e-163 542.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF2990 PF11693.8 KFM59792.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) UL45 PF05473.12 KFM59795.1 - 2.8e-09 36.9 0.0 3.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 KFM59795.1 - 2.3e-05 25.1 0.0 4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain zf-H2C2_2 PF13465.6 KFM59796.1 - 2e-105 340.9 96.2 2.8e-10 40.2 1.4 15.2 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59796.1 - 7.6e-72 234.0 133.8 8.4e-07 29.1 0.5 15.1 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59796.1 - 2.6e-50 164.7 121.4 0.00013 22.5 0.4 15.1 15 0 0 15 15 15 15 C2H2-type zinc finger zf-met PF12874.7 KFM59796.1 - 4.3e-26 90.5 131.6 0.0018 18.6 1.1 15.7 16 0 0 16 16 15 13 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM59796.1 - 2.5e-17 62.4 104.7 0.0026 17.7 0.3 16.9 17 0 0 17 17 17 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM59796.1 - 1.2e-13 51.0 109.0 0.0065 16.7 1.2 16.1 14 2 2 16 16 16 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM59796.1 - 1.3e-12 47.2 77.3 0.013 15.2 0.2 14.7 15 0 0 15 15 15 8 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM59796.1 - 2.3e-07 30.7 45.4 0.01 15.8 0.4 10.0 4 4 4 8 8 8 4 Adenylate kinase, active site lid GAGA PF09237.11 KFM59796.1 - 0.0002 21.1 36.9 0.69 9.8 0.0 10.6 3 2 7 12 12 12 4 GAGA factor BolA PF01722.18 KFM59796.1 - 0.00023 21.4 29.7 2.9 8.2 0.1 8.7 3 2 4 7 7 7 2 BolA-like protein DUF4825 PF16107.5 KFM59796.1 - 0.00059 19.9 0.0 14 5.9 0.0 5.1 2 2 4 6 6 6 0 Domain of unknown function (DUF4825) C1_1 PF00130.22 KFM59796.1 - 0.0015 18.3 75.3 0.58 10.1 2.7 11.3 4 4 7 11 11 11 5 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KFM59796.1 - 0.0049 17.0 72.6 1.1 9.4 1.0 13.3 1 1 13 14 14 14 4 KIAA1045 RING finger C1_4 PF07975.12 KFM59796.1 - 0.0078 16.4 76.3 1.7 8.9 3.0 9.4 4 1 4 10 10 10 4 TFIIH C1-like domain Mga PF05043.13 KFM59796.1 - 0.054 14.1 8.3 20 5.9 0.1 5.3 6 1 0 6 6 5 0 Mga helix-turn-helix domain zf-C2HC_2 PF13913.6 KFM59796.1 - 0.058 13.3 63.5 1.3 9.0 1.5 14.3 15 0 0 15 15 15 0 zinc-finger of a C2HC-type Baculo_IE-1 PF05290.11 KFM59796.1 - 0.1 12.6 56.1 1.2 9.1 0.1 9.2 1 1 6 7 7 7 0 Baculovirus immediate-early protein (IE-0) Rpr2 PF04032.16 KFM59796.1 - 0.12 12.7 71.8 1.5 9.1 1.9 9.2 1 1 5 7 7 7 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain FYVE PF01363.21 KFM59796.1 - 0.15 12.2 84.9 1.3 9.2 8.1 8.9 2 1 5 7 7 7 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM59796.1 - 1 10.1 66.7 0.22 12.3 1.6 7.9 1 1 5 8 8 8 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 KFM59796.1 - 1.6 8.8 57.3 2.5 8.2 0.2 13.7 13 2 1 14 14 14 0 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM59796.1 - 1.8 8.7 68.6 0.43 10.7 6.0 6.1 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-H2C2_2 PF13465.6 KFM59797.1 - 2.4e-53 176.3 66.4 4.2e-09 36.4 0.2 10.2 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59797.1 - 8.7e-35 117.2 77.9 0.0001 22.5 2.2 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59797.1 - 7.7e-34 113.4 68.1 6.5e-05 23.4 2.3 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM59797.1 - 3e-15 55.8 60.8 0.0028 17.6 1.0 9.7 9 1 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM59797.1 - 2.2e-14 53.3 67.9 0.006 16.9 1.4 9.3 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM59797.1 - 1.2e-13 50.9 52.1 0.034 14.5 0.6 9.3 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM59797.1 - 0.0015 18.7 10.0 2.4 8.5 0.6 5.4 2 2 3 5 5 5 2 BolA-like protein ADK_lid PF05191.14 KFM59797.1 - 0.06 13.3 19.9 1.3 9.1 0.2 6.1 3 2 1 4 4 4 0 Adenylate kinase, active site lid DUF3268 PF11672.8 KFM59797.1 - 0.069 13.5 0.6 0.069 13.5 0.6 4.2 3 1 1 4 4 4 0 zinc-finger-containing domain zinc_ribbon_15 PF17032.5 KFM59797.1 - 0.098 13.4 34.4 2.2 9.1 2.8 4.8 2 1 0 4 4 4 0 zinc-ribbon family zf-LYAR PF08790.11 KFM59797.1 - 0.19 11.7 0.1 0.19 11.7 0.1 6.0 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 KFM59797.1 - 0.27 11.6 52.7 1.3 9.4 11.6 7.3 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) Scramblase PF03803.15 KFM59797.1 - 1.5 8.0 12.8 5.2 6.3 0.9 3.2 1 1 1 3 3 3 0 Scramblase zf-C2HC_2 PF13913.6 KFM59797.1 - 1.7 8.7 52.8 0.15 12.0 1.0 8.7 9 0 0 9 9 9 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFM59797.1 - 2.2 8.4 42.3 8.4 6.6 0.2 8.4 2 2 6 8 8 8 0 KIAA1045 RING finger zf_UBZ PF18439.1 KFM59797.1 - 2.6 7.7 38.5 2 8.0 0.1 8.9 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 KFM59797.1 - 3.1 7.6 55.9 1.3 8.8 0.9 9.9 9 1 0 9 9 9 0 C2H2-type zinc-finger domain zf-AN1 PF01428.16 KFM59797.1 - 5 7.4 49.9 0.57 10.4 0.6 9.2 7 2 2 9 9 9 0 AN1-like Zinc finger C1_2 PF03107.16 KFM59797.1 - 6.6 7.1 56.0 25 5.3 7.9 8.3 3 3 2 5 5 5 0 C1 domain DUF2256 PF10013.9 KFM59797.1 - 9.3 6.5 37.0 16 5.7 0.1 8.8 8 1 1 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) RVT_1 PF00078.27 KFM59799.1 - 8.2e-46 156.3 0.0 1.8e-45 155.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM59799.1 - 4.2e-14 52.4 0.0 4.2e-14 52.4 0.0 2.8 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM59799.1 - 2.2e-08 33.9 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PRE_C2HC PF07530.11 KFM59799.1 - 0.00013 22.0 0.1 0.00035 20.6 0.1 1.7 1 0 0 1 1 1 1 Associated with zinc fingers Imm44 PF15571.6 KFM59799.1 - 4.5 7.5 7.8 0.81 9.9 1.8 2.4 2 0 0 2 2 2 0 Immunity protein 44 HTH_Tnp_Tc3_2 PF01498.18 KFM59800.1 - 3.4e-21 75.3 4.9 4.9e-10 39.5 1.0 2.3 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM59800.1 - 5.4e-15 55.4 0.0 3.8e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease AntA PF08346.12 KFM59800.1 - 0.091 13.3 0.4 1.4 9.6 0.2 2.2 2 0 0 2 2 2 0 AntA/AntB antirepressor SNF2_N PF00176.23 KFM59802.1 - 5.9e-56 189.7 0.3 1.2e-55 188.7 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM59802.1 - 1.2e-16 61.1 0.0 4.6e-16 59.1 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM59802.1 - 9.4e-05 22.5 0.2 0.00053 20.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Tox-HDC PF15656.6 KFM59802.1 - 0.049 13.8 2.4 1.7 8.9 0.1 3.7 4 0 0 4 4 4 0 Toxin with a H, D/N and C signature BRK PF07533.16 KFM59803.1 - 0.092 12.4 2.1 0.75 9.5 0.4 2.3 2 0 0 2 2 2 0 BRK domain IGFBP PF00219.18 KFM59804.1 - 2e-06 28.4 18.0 2.6e-06 28.0 18.0 1.2 1 0 0 1 1 1 1 Insulin-like growth factor binding protein Neuroparsin PF07327.11 KFM59804.1 - 0.22 12.0 8.3 0.29 11.6 8.3 1.2 1 0 0 1 1 1 0 Neuroparsin Hormone_recep PF00104.30 KFM59806.1 - 2.7e-42 144.7 0.3 4.9e-42 143.8 0.3 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFM59806.1 - 3.9e-29 100.9 18.3 6.7e-29 100.2 18.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PHD_like PF12910.7 KFM59806.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system WD40 PF00400.32 KFM59807.1 - 3.4e-16 59.3 1.9 6.7e-05 23.6 0.1 4.7 4 1 0 4 4 4 3 WD domain, G-beta repeat PCIF1_WW PF12237.8 KFM59810.1 - 7.4e-61 204.7 1.4 9.3e-61 204.4 1.4 1.1 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain SBF PF01758.16 KFM59811.1 - 3e-32 111.9 10.0 3e-32 111.9 10.0 2.1 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF4371 PF14291.6 KFM59813.1 - 7.3e-13 48.7 0.0 9.3e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF2649 PF10854.8 KFM59813.1 - 0.16 12.3 1.0 2.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) SBF PF01758.16 KFM59814.1 - 3.9e-16 59.3 10.6 3.9e-16 59.3 10.6 1.9 1 1 1 2 2 2 1 Sodium Bile acid symporter family Iron_permease PF04120.12 KFM59814.1 - 0.073 12.8 3.2 0.099 12.4 2.1 1.8 2 0 0 2 2 2 0 Low affinity iron permease DUF3938 PF13074.6 KFM59814.1 - 0.16 12.3 2.5 0.38 11.0 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Pox_A14 PF05767.12 KFM59815.1 - 0.002 18.2 0.2 0.025 14.7 0.1 2.2 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 DUF2417 PF10329.9 KFM59815.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) PAS_3 PF08447.12 KFM59818.1 - 6.8e-25 87.2 0.0 4.9e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFM59818.1 - 1.1e-18 67.3 0.0 8.8e-15 54.8 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KFM59818.1 - 8.6e-11 41.8 0.0 1.1e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFM59818.1 - 4.9e-07 29.9 0.1 0.00041 20.6 0.0 2.4 2 0 0 2 2 2 2 PAS domain HLH PF00010.26 KFM59818.1 - 0.0047 16.9 0.3 0.0095 15.9 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 KFM59818.1 - 0.013 15.7 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 PAS fold C8 PF08742.11 KFM59818.1 - 0.58 10.6 4.6 1.6 9.2 0.0 3.1 2 1 1 3 3 3 0 C8 domain Macoilin PF09726.9 KFM59818.1 - 4.4 5.7 7.8 6.8 5.1 7.8 1.2 1 0 0 1 1 1 0 Macoilin family zf-C2H2 PF00096.26 KFM59819.1 - 1.6e-05 25.1 122.1 0.018 15.5 1.5 14.2 14 0 0 14 14 14 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM59819.1 - 0.0047 17.3 1.9 0.0047 17.3 1.9 14.0 16 0 0 16 16 16 7 Zinc-finger double domain Peptidase_M14 PF00246.24 KFM59821.1 - 3.6e-36 125.5 0.0 3.8e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase TMEM154 PF15102.6 KFM59822.1 - 0.00011 22.2 2.9 0.00021 21.2 2.9 1.6 1 1 0 1 1 1 1 TMEM154 protein family ECSCR PF15820.5 KFM59822.1 - 0.005 16.6 0.1 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator DUF4366 PF14283.6 KFM59822.1 - 0.0099 15.9 0.3 0.016 15.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) EVI2A PF05399.11 KFM59822.1 - 0.011 15.4 0.9 0.016 14.8 0.9 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Insulin_TMD PF17870.1 KFM59822.1 - 0.022 14.8 1.2 0.087 12.9 0.2 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 KFM59822.1 - 0.035 14.4 0.1 0.08 13.2 0.1 1.8 1 1 0 1 1 1 0 Orf78 (ac78) DUF1556 PF07590.11 KFM59822.1 - 0.073 13.4 0.2 0.26 11.6 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1556) HTH_Tnp_Tc3_2 PF01498.18 KFM59823.1 - 3.3e-16 59.3 3.6 5.2e-16 58.6 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM59823.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59823.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59823.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59823.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Y_phosphatase PF00102.27 KFM59824.1 - 1.3e-06 28.2 0.1 1.4e-06 28.1 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zf-H2C2_2 PF13465.6 KFM59825.1 - 4e-89 289.4 76.5 1.7e-08 34.5 0.2 12.4 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59825.1 - 2.1e-58 191.6 97.6 3.2e-06 27.3 2.3 11.4 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59825.1 - 1.3e-40 134.6 93.0 0.0012 19.5 1.9 11.4 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM59825.1 - 8.4e-36 121.3 93.3 0.00015 22.0 1.8 11.4 11 0 0 11 11 11 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM59825.1 - 1.9e-17 62.8 92.6 0.00052 19.9 1.0 12.2 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM59825.1 - 1.9e-17 63.0 65.9 0.0096 16.2 0.2 11.6 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM59825.1 - 1.8e-14 53.2 53.5 0.042 13.6 0.2 11.3 11 0 0 11 11 11 5 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM59825.1 - 5.8e-08 32.4 47.2 4.7 7.2 0.1 12.4 12 0 0 12 12 12 2 zinc-finger of a C2HC-type Tox-HNH-HHH PF15637.6 KFM59825.1 - 6.3e-07 29.5 5.0 0.8 9.9 0.1 5.3 1 1 5 6 6 6 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif ADK_lid PF05191.14 KFM59825.1 - 1.6e-05 24.7 41.4 0.06 13.3 1.9 6.7 3 1 4 7 7 7 4 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM59825.1 - 0.00014 21.9 41.7 0.4 10.8 0.2 10.9 11 0 0 11 11 11 1 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 KFM59825.1 - 0.00014 21.9 59.3 0.58 10.3 8.9 6.1 1 1 3 5 5 5 3 FYVE zinc finger zf-HIT PF04438.16 KFM59825.1 - 0.00031 20.5 68.9 0.12 12.2 1.1 11.0 11 0 0 11 11 11 3 HIT zinc finger zf-CHCC PF10276.9 KFM59825.1 - 0.00032 20.7 13.3 22 5.2 0.0 9.2 11 0 0 11 11 11 0 Zinc-finger domain DUF3396 PF11876.8 KFM59825.1 - 0.0026 17.3 0.0 44 3.5 0.0 4.7 2 1 4 6 6 6 0 Protein of unknown function (DUF3396) BolA PF01722.18 KFM59825.1 - 0.041 14.2 12.4 3.2 8.1 0.2 5.9 1 1 4 6 6 6 0 BolA-like protein C1_1 PF00130.22 KFM59825.1 - 0.043 13.7 62.4 5.7 6.9 0.4 10.6 2 1 7 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TarS_C1 PF18674.1 KFM59825.1 - 0.062 13.2 0.0 57 3.6 0.0 3.5 3 0 0 3 3 3 0 TarS beta-glycosyltransferase C-terminal domain 1 GATase_2 PF00310.21 KFM59825.1 - 0.071 11.8 0.5 0.47 9.1 0.1 2.3 1 1 0 2 2 2 0 Glutamine amidotransferases class-II zf-DBF PF07535.12 KFM59825.1 - 0.22 11.6 57.7 14 5.9 0.1 11.1 10 1 1 11 11 11 0 DBF zinc finger YyzF PF14116.6 KFM59825.1 - 0.24 11.4 40.6 8.7 6.5 0.8 10.5 11 0 0 11 11 11 0 YyzF-like protein zf-Sec23_Sec24 PF04810.15 KFM59825.1 - 0.45 10.6 52.3 0.89 9.7 0.2 11.4 7 3 5 12 12 12 0 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM59825.1 - 2.2 8.2 48.0 3 7.7 0.1 10.4 2 2 9 11 11 11 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM59825.1 - 2.4 9.0 48.2 5 7.9 1.7 6.2 1 1 6 8 8 8 0 zinc-ribbon family GAGA PF09237.11 KFM59825.1 - 3.1 7.7 29.6 2.3 8.1 0.5 8.1 2 1 8 10 10 10 0 GAGA factor Zn-ribbon_8 PF09723.10 KFM59825.1 - 4 7.6 41.9 13 6.0 1.1 7.8 2 2 4 6 6 5 0 Zinc ribbon domain PqqA PF08042.11 KFM59825.1 - 4.7 7.4 7.5 4.8e+02 1.0 0.0 6.0 9 0 0 9 9 7 0 PqqA family GST_N PF02798.20 KFM59826.1 - 2.9e-17 62.8 0.1 5.8e-16 58.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFM59826.1 - 6.7e-15 55.1 2.0 1.2e-14 54.3 2.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM59826.1 - 9.9e-09 35.3 0.4 9.9e-09 35.3 0.4 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFM59826.1 - 0.0051 16.6 0.7 0.014 15.2 0.7 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM59826.1 - 0.023 15.1 0.1 0.082 13.3 0.1 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF2852 PF11014.8 KFM59826.1 - 0.073 13.2 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) MYEOV2 PF15004.6 KFM59826.1 - 0.31 11.5 1.3 0.8 10.2 1.0 2.0 1 1 0 1 1 1 0 Myeloma-overexpressed-like SEA PF01390.20 KFM59827.1 - 0.022 14.8 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 SEA domain Ldl_recept_a PF00057.18 KFM59828.1 - 6.8e-19 67.8 45.4 5.8e-08 32.8 16.8 3.3 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A CHD5 PF04420.14 KFM59828.1 - 0.041 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 CHD5-like protein Trypsin PF00089.26 KFM59829.1 - 7.6e-67 225.4 0.0 8.9e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM59829.1 - 2.6e-10 40.7 0.0 4.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.18 KFM59829.1 - 4.6e-08 33.1 11.9 4.6e-08 33.1 11.9 2.4 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A LIM PF00412.22 KFM59833.1 - 5.1e-32 109.9 22.7 5.7e-16 58.5 5.4 2.5 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFM59833.1 - 2.4e-19 68.9 3.6 4.5e-19 68.0 3.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM59833.1 - 4.5e-05 23.3 0.1 0.0001 22.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFM59833.1 - 0.00099 18.5 0.1 0.0027 17.1 0.1 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Glyco_hydro_18 PF00704.28 KFM59834.1 - 2.8e-12 47.0 0.0 3.2e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KFM59835.1 - 4.9e-16 59.3 0.0 5.9e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HTH_Tnp_Tc5 PF03221.16 KFM59836.1 - 1.8e-15 56.7 0.0 2.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain KH_1 PF00013.29 KFM59838.1 - 1.4e-67 223.4 11.9 3.2e-17 62.1 0.2 4.4 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFM59838.1 - 1.3e-18 66.6 7.9 3.5e-05 23.5 0.2 4.5 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFM59838.1 - 2.3e-12 46.6 7.2 0.0056 16.5 0.0 4.6 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 KFM59838.1 - 0.011 15.8 6.2 1.8 8.7 0.1 4.5 4 0 0 4 4 4 0 NusA-like KH domain GST_C_4 PF14834.6 KFM59838.1 - 0.08 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2464 PF10240.9 KFM59839.1 - 0.0014 18.3 0.1 0.0016 18.0 0.1 1.1 1 0 0 1 1 1 1 Multivesicular body subunit 12 Bromodomain PF00439.25 KFM59840.1 - 2.2e-39 133.4 2.6 1.7e-19 69.6 0.0 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFM59840.1 - 4.8e-27 93.9 0.1 4.8e-27 93.9 0.1 3.1 4 0 0 4 4 4 1 Bromodomain extra-terminal - transcription regulation BRD4_CDT PF17105.5 KFM59840.1 - 2.5e-15 55.8 6.3 2.5e-15 55.8 6.3 3.7 2 1 2 4 4 4 1 C-terminal domain of bromodomain protein 4 CCDC66 PF15236.6 KFM59840.1 - 0.0058 16.5 21.5 0.0058 16.5 21.5 5.1 5 0 0 5 5 5 1 Coiled-coil domain-containing protein 66 DUF1501 PF07394.12 KFM59840.1 - 0.82 8.7 8.7 1.8 7.5 8.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) HTH_Tnp_Tc3_2 PF01498.18 KFM59843.1 - 5.3e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59843.1 - 1.4e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59843.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59843.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59843.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM59844.1 - 3.2e-16 59.3 6.5 6.6e-16 58.3 3.9 2.1 2 0 0 2 2 2 1 Transposase HTH_7 PF02796.15 KFM59844.1 - 1e-05 25.5 0.8 0.0025 17.8 0.0 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM59844.1 - 2.9e-05 24.6 2.5 2.9e-05 24.6 2.5 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM59844.1 - 0.00013 21.6 9.1 0.00036 20.2 0.0 3.6 3 1 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM59844.1 - 0.00034 20.7 2.1 0.00039 20.5 0.0 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain CENP-B_N PF04218.13 KFM59844.1 - 0.0018 17.8 0.0 0.005 16.4 0.0 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 KFM59844.1 - 0.0036 17.1 0.0 0.015 15.0 0.0 2.1 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KFM59844.1 - 0.0065 16.3 0.4 0.037 13.9 0.0 2.4 2 1 0 2 2 2 1 MarR family HTH_38 PF13936.6 KFM59844.1 - 0.017 14.8 0.1 0.065 13.0 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM59844.1 - 0.053 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Tc3 transposase Sigma70_r4 PF04545.16 KFM59844.1 - 0.058 12.9 1.2 1.5 8.4 0.1 2.6 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_21 PF13276.6 KFM59844.1 - 0.39 10.9 3.8 4.6 7.4 1.1 2.5 2 0 0 2 2 2 0 HTH-like domain Acetyltransf_18 PF18014.1 KFM59845.1 - 1.4e-11 44.3 0.0 2.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM59845.1 - 1.1e-09 38.5 0.0 1.1e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM59845.1 - 7e-09 35.7 0.0 7.4e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM59845.1 - 1.5e-06 28.5 0.1 1.2e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KFM59845.1 - 0.0058 16.2 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 KFM59845.1 - 0.039 14.1 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF1759 PF03564.15 KFM59846.1 - 2.5e-29 102.1 1.8 2.5e-29 102.1 1.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1759) DUF3169 PF11368.8 KFM59846.1 - 0.072 12.6 0.5 0.13 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) PriX PF18689.1 KFM59846.1 - 8.1 6.9 8.8 3.8 7.9 3.3 3.0 2 2 3 5 5 5 0 Primase X Acetyltransf_18 PF18014.1 KFM59847.1 - 3.3e-12 46.3 0.0 8.1e-12 45.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM59847.1 - 1.1e-11 45.0 0.0 2.5e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM59847.1 - 1.3e-07 31.6 0.0 5.6e-07 29.6 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM59847.1 - 7.1e-06 26.4 0.0 2.7e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM59847.1 - 0.01 15.8 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.7 KFM59847.1 - 0.025 14.7 0.0 0.25 11.4 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ig_3 PF13927.6 KFM59848.1 - 6.3e-26 90.8 1.7 4.2e-08 33.7 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM59848.1 - 6.1e-18 64.8 0.9 1.1e-07 31.9 0.5 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM59848.1 - 2.3e-17 63.1 1.0 0.00022 21.5 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM59848.1 - 2.5e-16 59.5 0.1 8.9e-06 25.7 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFM59848.1 - 5.8e-10 39.1 0.3 1.9e-08 34.2 0.1 2.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM59848.1 - 0.1 12.9 0.2 6.9 7.0 0.0 3.2 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain HTH_Tnp_Tc3_2 PF01498.18 KFM59849.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59849.1 - 1.1e-12 48.0 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59849.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59849.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59849.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Carn_acyltransf PF00755.20 KFM59850.1 - 1.4e-30 106.5 0.1 1.7e-30 106.3 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sprouty PF05210.13 KFM59851.1 - 7.8e-32 109.7 17.8 1.3e-31 109.0 17.8 1.4 1 0 0 1 1 1 1 Sprouty protein (Spry) WH1 PF00568.23 KFM59851.1 - 2.8e-12 46.6 0.0 4.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 WH1 domain HTH_Tnp_Tc3_2 PF01498.18 KFM59852.1 - 3.5e-16 59.2 3.3 4.3e-16 58.9 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59852.1 - 9e-14 51.4 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease AMP-binding PF00501.28 KFM59853.1 - 1.1e-19 70.4 0.0 1.1e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KFM59854.1 - 5.4e-26 91.1 0.0 6.2e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme NAD_kinase PF01513.21 KFM59855.1 - 7.8e-13 48.3 0.0 1.6e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFM59855.1 - 0.032 13.8 0.0 0.087 12.4 0.0 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Peptidase_S51 PF03575.17 KFM59855.1 - 0.047 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 TPALS PF18178.1 KFM59855.1 - 0.076 12.4 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 TIR- and PNP-associating SLOG family Cation_efflux PF01545.21 KFM59856.1 - 2.2e-51 174.5 4.2 2.6e-51 174.2 4.2 1.1 1 0 0 1 1 1 1 Cation efflux family GRP PF07172.11 KFM59856.1 - 0.00055 20.6 2.1 0.0013 19.3 2.1 1.6 1 0 0 1 1 1 1 Glycine rich protein family Dak2 PF02734.17 KFM59856.1 - 0.48 10.3 1.7 1.1 9.1 0.1 1.9 1 1 1 2 2 2 0 DAK2 domain MSA_2 PF00985.17 KFM59856.1 - 2.8 8.3 7.5 4 7.8 7.5 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family HTH_Tnp_Tc3_2 PF01498.18 KFM59858.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59858.1 - 7.5e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59858.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59858.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59858.1 - 1.8 9.2 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain CAP PF00188.26 KFM59859.1 - 2.2e-22 80.2 0.2 3.2e-22 79.7 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rap_GAP PF02145.15 KFM59861.1 - 1.8e-67 226.5 0.0 2.6e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP CBM_14 PF01607.24 KFM59864.1 - 9.8e-160 518.8 325.1 6.3e-11 42.3 9.3 22.5 22 0 0 22 22 22 22 Chitin binding Peritrophin-A domain Acyl_transf_3 PF01757.22 KFM59865.1 - 1.2e-06 27.9 8.0 1.2e-06 27.9 8.0 2.1 3 0 0 3 3 3 1 Acyltransferase family DUF4710 PF15828.5 KFM59865.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DUF4576 PF15144.6 KFM59865.1 - 0.19 11.6 0.4 1 9.2 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4576) zf-H2C2_2 PF13465.6 KFM59868.1 - 1.3e-45 151.8 53.4 2.2e-07 31.0 2.8 7.2 7 0 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59868.1 - 4.7e-29 99.2 66.1 3.7e-06 27.1 1.7 7.2 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59868.1 - 5.8e-21 73.4 60.1 0.00053 20.6 3.8 7.2 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM59868.1 - 4.2e-14 52.4 47.9 0.0021 18.4 1.8 7.4 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM59868.1 - 1.6e-08 34.2 44.6 0.019 14.7 0.4 7.4 7 0 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM59868.1 - 7.8e-07 29.0 48.2 0.00067 19.6 0.4 7.3 6 1 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM59868.1 - 2.4e-05 24.5 42.4 0.033 14.5 1.0 7.3 6 1 1 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM59868.1 - 0.0016 18.2 26.6 0.46 10.4 0.3 6.1 2 1 4 6 6 6 1 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM59868.1 - 0.0036 17.5 7.5 1.9 8.8 1.4 3.4 2 1 0 2 2 2 2 BolA-like protein GAGA PF09237.11 KFM59868.1 - 0.0059 16.4 19.3 1 9.2 0.2 5.8 1 1 6 7 7 7 1 GAGA factor DUF2256 PF10013.9 KFM59868.1 - 0.054 13.6 22.2 7.6 6.7 0.0 6.2 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM59868.1 - 0.056 13.4 22.5 0.064 13.3 1.0 4.8 2 1 3 5 5 5 0 Adenylate kinase, active site lid FYVE PF01363.21 KFM59868.1 - 0.065 13.4 32.5 0.092 12.9 9.7 4.2 3 1 0 3 3 3 0 FYVE zinc finger BHD_1 PF10403.9 KFM59868.1 - 0.15 11.9 0.4 47 3.9 0.0 3.4 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 1 DZR PF12773.7 KFM59868.1 - 0.18 11.9 23.0 3.1 7.9 4.4 4.1 2 2 2 4 4 4 0 Double zinc ribbon PqqA PF08042.11 KFM59868.1 - 0.35 11.0 0.7 2.5e+02 1.9 0.0 4.0 5 0 0 5 5 5 0 PqqA family zf-RRPl_C4 PF17026.5 KFM59868.1 - 0.37 10.9 21.5 2.5 8.3 3.6 3.3 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 KFM59868.1 - 0.37 10.7 37.7 5.5 7.0 0.7 5.7 2 2 4 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YyzF PF14116.6 KFM59868.1 - 0.43 10.6 19.4 14 5.8 0.2 5.8 6 0 0 6 6 6 0 YyzF-like protein zf-DBF PF07535.12 KFM59868.1 - 0.88 9.7 23.8 5.4 7.2 0.1 6.1 6 0 0 6 6 6 0 DBF zinc finger zinc_ribbon_15 PF17032.5 KFM59868.1 - 1.1 10.0 23.4 18 6.1 3.6 3.9 1 1 2 3 3 3 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 KFM59868.1 - 3.9 7.6 25.3 4.3 7.5 2.0 6.0 3 2 3 6 6 6 0 Sec23/Sec24 zinc finger Rpr2 PF04032.16 KFM59869.1 - 1.3e-13 51.1 2.8 1.6e-13 50.7 2.8 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_7 PF02591.15 KFM59869.1 - 0.011 15.8 0.4 0.021 15.0 0.4 1.5 1 0 0 1 1 1 0 C4-type zinc ribbon domain zf-Sec23_Sec24 PF04810.15 KFM59869.1 - 0.035 14.1 0.7 0.086 12.9 0.7 1.7 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger BCL9 PF11502.8 KFM59870.1 - 3.2e-14 52.4 13.3 1.2e-13 50.6 13.3 2.1 1 0 0 1 1 1 1 B-cell lymphoma 9 protein PIF1 PF05970.14 KFM59871.1 - 1.7e-47 162.3 0.0 2.3e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFM59871.1 - 3.6e-07 30.1 0.0 6.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF4559 PF15112.6 KFM59871.1 - 0.054 13.2 0.2 0.095 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Atg8 PF02991.16 KFM59872.1 - 6.2e-42 142.0 0.0 7.1e-42 141.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFM59872.1 - 1.5e-05 25.3 0.0 1.9e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Laminin_G_2 PF02210.24 KFM59873.1 - 7.5e-27 94.4 0.2 8.3e-27 94.3 0.2 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM59873.1 - 1.2e-26 93.4 0.1 1.5e-26 93.2 0.1 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFM59873.1 - 0.0089 16.2 0.1 0.011 15.9 0.1 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 KFM59874.1 - 1.2e-49 167.8 0.0 1.6e-28 99.5 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 KFM59874.1 - 5e-47 159.6 0.0 3.9e-27 95.3 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFM59874.1 - 1.1e-11 44.8 31.7 0.00072 19.8 2.7 3.7 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 KFM59874.1 - 0.00011 22.7 28.4 0.041 14.5 4.3 3.8 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_2 PF07974.13 KFM59874.1 - 0.009 16.4 39.1 0.14 12.5 9.1 3.5 3 0 0 3 3 3 2 EGF-like domain Pneumo_att_G PF05539.11 KFM59874.1 - 0.03 13.9 4.0 0.055 13.1 4.0 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G EamA PF00892.20 KFM59875.1 - 2e-17 63.6 24.4 4.8e-10 39.7 13.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KFM59875.1 - 0.003 16.8 0.8 0.003 16.8 0.8 1.5 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport RhoGEF PF00621.20 KFM59876.1 - 6e-34 117.9 4.0 6e-34 117.9 4.0 2.4 2 0 0 2 2 2 1 RhoGEF domain DUF4485 PF14846.6 KFM59876.1 - 0.12 12.4 2.1 1.8 8.7 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) PH_13 PF16652.5 KFM59876.1 - 0.15 11.8 0.0 0.15 11.8 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain DUF2796 PF10986.8 KFM59876.1 - 2.6 8.0 8.5 8.4 6.3 8.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) HflK_N PF12221.8 KFM59877.1 - 0.074 13.1 1.7 0.17 11.9 1.7 1.7 1 1 0 1 1 1 0 Bacterial membrane protein N terminal ANF_receptor PF01094.28 KFM59878.1 - 1.4e-13 50.7 0.0 1.5e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 KFM59880.1 - 7.4e-07 28.6 0.1 9.7e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFM59881.1 - 1.1e-45 155.2 0.6 1.2e-45 155.0 0.6 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFM59881.1 - 1.3e-15 57.6 0.1 2.9e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM59881.1 - 1.4e-15 57.4 0.0 2.3e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF3443 PF11925.8 KFM59881.1 - 0.054 12.3 0.0 0.19 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3443) HTH_Tnp_Tc3_2 PF01498.18 KFM59882.1 - 2.5e-16 59.7 2.2 5.1e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59882.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease TFIIA_gamma_N PF02268.16 KFM59883.1 - 1.4e-24 85.9 0.2 1.9e-24 85.4 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain CarS-like PF01864.17 KFM59883.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 CDP-archaeol synthase Thioredoxin PF00085.20 KFM59884.1 - 2e-19 69.5 0.0 3.2e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KFM59884.1 - 0.0026 17.6 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 KFM59884.1 - 0.0082 15.5 0.1 0.016 14.6 0.1 1.5 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFM59884.1 - 0.02 15.3 0.1 0.071 13.6 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain FAM176 PF14851.6 KFM59884.1 - 0.062 13.0 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 FAM176 family GP41 PF00517.17 KFM59884.1 - 0.2 11.6 0.4 0.56 10.1 0.1 1.8 2 0 0 2 2 2 0 Retroviral envelope protein DDE_3 PF13358.6 KFM59886.1 - 3.9e-07 29.9 0.0 4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM59887.1 - 3.2e-12 46.4 0.0 5.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59887.1 - 1.4e-10 41.3 1.0 2.1e-10 40.7 1.0 1.3 1 0 0 1 1 1 1 Transposase DPPIV_N PF00930.21 KFM59889.1 - 5.1e-33 114.3 2.4 5.6e-33 114.2 2.4 1.0 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1968 PF09291.10 KFM59889.1 - 0.028 14.5 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1968) DUF3751 PF12571.8 KFM59889.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage tail-collar fibre protein DUF5641 PF18701.1 KFM59890.1 - 1.2e-17 63.8 0.0 1.7e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) P66_CC PF16563.5 KFM59890.1 - 1.2 8.9 4.9 4.1 7.1 0.1 3.0 3 0 0 3 3 3 0 Coiled-coil and interaction region of P66A and P66B with MBD2 DUF1640 PF07798.11 KFM59891.1 - 0.0018 18.4 13.1 0.0033 17.5 13.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1664 PF07889.12 KFM59891.1 - 0.0046 17.0 12.2 0.055 13.5 12.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) RAP-1 PF03085.15 KFM59891.1 - 0.014 15.1 2.0 0.017 14.8 2.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IMD PF08397.11 KFM59891.1 - 0.015 14.7 7.5 0.02 14.3 7.5 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain WXG100 PF06013.12 KFM59891.1 - 0.015 15.5 8.0 0.28 11.5 3.3 3.1 1 1 2 3 3 3 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 KFM59891.1 - 0.016 15.6 1.6 1 9.8 1.6 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.18 KFM59891.1 - 0.022 14.7 8.1 0.077 12.9 8.1 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM59891.1 - 0.025 14.6 0.1 0.52 10.4 0.1 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KFM59891.1 - 0.037 12.9 13.7 0.043 12.7 13.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KFM59891.1 - 0.05 13.8 9.0 0.1 12.8 9.0 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 KFM59891.1 - 0.051 11.5 3.5 0.056 11.4 3.5 1.1 1 0 0 1 1 1 0 Prominin ABC_tran_CTD PF16326.5 KFM59891.1 - 0.059 13.6 0.0 0.059 13.6 0.0 3.1 1 1 1 2 2 1 0 ABC transporter C-terminal domain HSBP1 PF06825.12 KFM59891.1 - 0.06 13.2 4.2 0.27 11.1 0.2 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 ApoO PF09769.9 KFM59891.1 - 0.061 13.3 0.8 2.2 8.3 0.1 2.2 1 1 1 2 2 2 0 Apolipoprotein O FH2 PF02181.23 KFM59891.1 - 0.066 12.3 8.9 0.078 12.1 8.9 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain PheRS_DBD2 PF18554.1 KFM59891.1 - 0.11 12.5 1.9 27 4.9 0.3 3.6 3 0 0 3 3 3 0 PheRS DNA binding domain 2 Mis12 PF05859.12 KFM59891.1 - 0.11 12.5 4.9 0.15 12.2 4.9 1.3 1 0 0 1 1 1 0 Mis12 protein FIN1 PF17300.2 KFM59891.1 - 0.13 11.8 9.5 0.15 11.5 9.5 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Spore_III_AB PF09548.10 KFM59891.1 - 0.14 12.3 7.0 0.21 11.7 7.0 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) FlaC_arch PF05377.11 KFM59891.1 - 0.15 12.5 0.4 0.15 12.5 0.4 3.6 1 1 1 2 2 1 0 Flagella accessory protein C (FlaC) DUF3560 PF12083.8 KFM59891.1 - 0.15 12.2 7.0 0.19 11.9 5.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3560) Prefoldin_3 PF13758.6 KFM59891.1 - 0.2 11.8 10.6 0.3 11.2 10.6 1.4 1 1 0 1 1 1 0 Prefoldin subunit BCAS2 PF05700.11 KFM59891.1 - 0.22 11.2 8.1 0.16 11.6 6.4 1.6 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Z1 PF10593.9 KFM59891.1 - 0.24 10.8 5.1 0.29 10.6 5.1 1.2 1 0 0 1 1 1 0 Z1 domain PIN_8 PF18476.1 KFM59891.1 - 0.28 11.0 7.9 0.34 10.8 7.9 1.2 1 0 0 1 1 1 0 PIN like domain Phasin PF05597.11 KFM59891.1 - 0.29 11.1 11.6 1.6 8.8 10.9 2.0 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.13 KFM59891.1 - 0.33 11.6 5.2 0.48 11.1 1.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) BLOC1_2 PF10046.9 KFM59891.1 - 0.33 11.3 9.7 3.7 7.9 9.9 2.3 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PP_kinase_N PF13089.6 KFM59891.1 - 0.35 11.2 5.3 0.26 11.7 3.5 1.6 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain DUF737 PF05300.11 KFM59891.1 - 0.88 9.9 14.4 1.1 9.6 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) TMPIT PF07851.13 KFM59891.1 - 1.4 8.1 8.8 1.8 7.7 8.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein MtrG PF04210.13 KFM59891.1 - 1.4 8.9 5.4 1 9.3 0.2 2.5 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2884 PF11101.8 KFM59891.1 - 1.7 8.1 15.0 1.8 8.0 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF1451 PF07295.11 KFM59891.1 - 1.7 8.6 8.8 3.6 7.6 8.8 1.6 1 1 0 1 1 1 0 Zinc-ribbon containing domain COG2 PF06148.11 KFM59891.1 - 1.8 8.7 13.5 0.99 9.5 0.3 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF16 PF01519.16 KFM59891.1 - 1.9 9.0 11.9 1.6 9.2 10.6 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 XhlA PF10779.9 KFM59891.1 - 5.9 7.2 13.8 3.4 7.9 0.1 3.2 1 1 1 2 2 2 0 Haemolysin XhlA zf-RING_2 PF13639.6 KFM59892.1 - 1.7e-09 37.8 4.7 2.4e-09 37.3 4.7 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFM59892.1 - 2.2e-07 30.5 4.4 3.4e-07 29.9 4.4 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFM59892.1 - 0.00023 21.1 4.5 0.00033 20.6 4.5 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFM59892.1 - 0.00026 20.7 4.4 0.00037 20.3 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFM59892.1 - 0.00081 19.0 3.2 0.001 18.7 3.2 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KFM59892.1 - 0.00091 19.3 2.5 0.0019 18.3 2.5 1.6 1 1 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.7 KFM59892.1 - 0.0036 17.5 5.0 0.0081 16.4 5.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain Vps39_2 PF10367.9 KFM59892.1 - 0.0038 17.7 0.3 0.0043 17.5 0.3 1.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING-like PF08746.11 KFM59892.1 - 0.009 16.3 3.9 0.012 15.9 3.9 1.2 1 0 0 1 1 1 1 RING-like domain FANCL_C PF11793.8 KFM59892.1 - 0.015 15.4 3.4 0.032 14.4 3.4 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.25 KFM59892.1 - 0.025 14.4 5.0 0.025 14.4 5.0 1.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KFM59892.1 - 0.041 13.8 3.5 0.055 13.4 3.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 KFM59892.1 - 0.1 12.6 3.9 0.13 12.2 3.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain FGE-sulfatase PF03781.16 KFM59894.1 - 9e-84 281.1 3.7 1.1e-83 280.8 3.7 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Peptidase_U49 PF10463.9 KFM59894.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase U49 KCNQ2_u3 PF16642.5 KFM59894.1 - 0.12 13.3 0.2 0.45 11.5 0.2 1.9 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 RVT_N PF13655.6 KFM59895.1 - 0.47 10.7 5.2 1.5 9.1 0.0 3.4 3 0 0 3 3 3 0 N-terminal domain of reverse transcriptase DUF4407 PF14362.6 KFM59895.1 - 2.3 7.5 12.6 0.61 9.4 7.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Prismane PF03063.20 KFM59897.1 - 0.0089 14.8 4.9 0.013 14.3 4.9 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family zf-BED PF02892.15 KFM59897.1 - 0.015 15.3 0.3 0.033 14.2 0.3 1.5 1 0 0 1 1 1 0 BED zinc finger CPSF73-100_C PF11718.8 KFM59898.1 - 2e-47 161.6 1.1 3.6e-47 160.7 1.1 1.5 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KFM59898.1 - 1.2e-34 118.8 0.0 2.6e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KFM59898.1 - 3.3e-21 75.0 0.1 7.1e-21 73.9 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 KFM59898.1 - 9.7e-19 67.6 0.0 6.1e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KFM59898.1 - 2.2e-16 60.4 0.1 3.7e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFM59898.1 - 1.5e-05 24.6 0.1 4.2e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFM59898.1 - 6.3e-05 22.9 0.1 0.00033 20.6 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFM59898.1 - 0.015 14.6 0.0 0.034 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative beta-lactamase-like family Gp58 PF07902.11 KFM59898.1 - 0.082 11.2 0.0 0.15 10.4 0.0 1.3 1 0 0 1 1 1 0 gp58-like protein PRE_C2HC PF07530.11 KFM59899.1 - 1.9e-06 27.9 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Associated with zinc fingers zf-CCHC_4 PF14392.6 KFM59899.1 - 0.011 15.4 1.5 0.011 15.4 1.5 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 KFM59899.1 - 0.21 11.7 2.8 0.38 10.9 2.8 1.5 1 0 0 1 1 1 0 Zinc knuckle HTH_Tnp_Tc3_2 PF01498.18 KFM59900.1 - 1.4e-07 31.6 1.3 1.4e-07 31.6 1.3 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59900.1 - 3.3e-06 26.9 0.0 6.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KFM59900.1 - 0.0011 18.6 1.5 0.0028 17.3 1.2 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_12 PF08461.10 KFM59900.1 - 0.0045 16.9 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain CxC6 PF18721.1 KFM59900.1 - 1.7 8.9 4.3 13 6.2 4.3 2.2 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases HTH_Tnp_Tc3_2 PF01498.18 KFM59901.1 - 1.6e-17 63.5 1.5 6.8e-16 58.3 2.2 2.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59901.1 - 1.7e-13 50.6 0.0 2.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM59901.1 - 3.2e-07 30.0 1.6 8.2e-07 28.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM59901.1 - 0.0031 17.2 0.5 0.0088 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM59901.1 - 2.9 8.6 15.6 0.15 12.7 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Vitellogenin_N PF01347.22 KFM59902.1 - 4.8e-83 279.6 0.0 6e-83 279.3 0.0 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 KFM59902.1 - 9.1e-39 133.5 0.4 1.6e-38 132.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) VWD PF00094.25 KFM59902.1 - 5e-19 69.1 0.1 5e-19 69.1 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type D domain HEAT_2 PF13646.6 KFM59902.1 - 1.4e-06 28.6 0.0 0.0031 17.8 0.0 2.4 1 1 2 3 3 3 3 HEAT repeats MAM PF00629.23 KFM59903.1 - 0.053 13.5 0.0 0.053 13.5 0.0 1.0 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu MAM PF00629.23 KFM59905.1 - 3.1e-18 66.2 0.0 3.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Ras PF00071.22 KFM59906.1 - 1.1e-45 155.1 0.0 2.2e-45 154.1 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM59906.1 - 2.1e-25 89.2 0.0 4.4e-24 85.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM59906.1 - 2e-12 46.9 0.1 1.7e-11 43.9 0.1 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family EF-hand_7 PF13499.6 KFM59906.1 - 2.5e-07 31.0 6.0 3e-07 30.8 2.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair MMR_HSR1 PF01926.23 KFM59906.1 - 4.7e-06 26.7 0.0 1.3e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_8 PF13833.6 KFM59906.1 - 9.7e-06 25.3 1.1 2.8e-05 23.8 1.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM59906.1 - 1e-05 24.7 3.1 0.0031 17.0 2.5 2.9 2 0 0 2 2 2 1 EF hand GTP_EFTU PF00009.27 KFM59906.1 - 1.1e-05 25.0 0.0 3.9e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.6 KFM59906.1 - 0.00082 19.1 3.2 0.44 10.6 2.2 2.9 2 0 0 2 2 2 1 EF-hand domain Gtr1_RagA PF04670.12 KFM59906.1 - 0.0021 17.4 0.1 0.005 16.2 0.1 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_5 PF13202.6 KFM59906.1 - 0.003 17.0 2.2 0.01 15.3 2.2 2.0 1 0 0 1 1 1 1 EF hand RsgA_GTPase PF03193.16 KFM59906.1 - 0.0035 17.3 0.1 1.6 8.6 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase EF-hand_11 PF08976.11 KFM59906.1 - 0.0081 17.0 0.1 0.025 15.4 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain Requiem_N PF14051.6 KFM59906.1 - 0.082 13.1 0.1 0.35 11.1 0.1 2.1 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. Pox_A_type_inc PF04508.12 KFM59906.1 - 0.22 11.4 5.2 2.1 8.4 0.1 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ER-remodelling PF14755.6 KFM59906.1 - 1.1 9.6 3.6 0.52 10.6 0.4 2.1 2 0 0 2 2 2 0 Intracellular membrane remodeller HSP70 PF00012.20 KFM59906.1 - 6.1 4.9 7.9 12 3.9 7.9 1.5 1 0 0 1 1 1 0 Hsp70 protein SH3_2 PF07653.17 KFM59907.1 - 3.7e-12 45.7 0.0 4.4e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFM59907.1 - 2.4e-06 27.3 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM59907.1 - 0.0024 17.5 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH2 PF00017.24 KFM59908.1 - 4.2e-19 68.4 0.0 5.3e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 KFM59908.1 - 0.032 13.6 0.0 3.6 6.9 0.0 1.9 1 1 1 2 2 2 0 SH2 domain GTP-bdg_M PF16360.5 KFM59909.1 - 4.7e-19 68.8 1.1 7.9e-19 68.0 1.1 1.4 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 KFM59909.1 - 2.2e-15 56.7 0.1 4.8e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.6 KFM59909.1 - 0.00029 21.5 0.3 0.00077 20.1 0.1 1.9 2 0 0 2 2 1 1 GTP-binding GTPase N-terminal TniB PF05621.11 KFM59909.1 - 0.0029 17.1 0.1 0.0064 15.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein FeoB_N PF02421.18 KFM59909.1 - 0.0065 16.0 0.3 0.015 14.9 0.3 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 KFM59909.1 - 0.0089 15.6 3.0 1.9 8.0 0.1 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KFM59909.1 - 0.012 15.2 1.7 4 6.9 0.1 2.9 1 1 2 3 3 3 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KFM59909.1 - 0.018 15.0 0.0 0.064 13.2 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 KFM59909.1 - 0.02 15.0 0.1 0.57 10.2 0.0 2.3 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.6 KFM59909.1 - 0.028 14.8 0.0 0.059 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KFM59909.1 - 0.029 14.4 0.0 0.088 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 KFM59909.1 - 0.032 14.1 0.4 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 KFM59909.1 - 0.04 14.4 0.0 0.11 13.1 0.0 1.9 1 1 0 1 1 1 0 ABC transporter CCDC-167 PF15188.6 KFM59909.1 - 0.048 14.0 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PduV-EutP PF10662.9 KFM59909.1 - 0.058 13.1 0.0 0.24 11.1 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 KFM59909.1 - 0.071 12.9 0.9 6.7 6.5 0.1 3.0 2 1 1 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 KFM59909.1 - 0.075 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SRPRB PF09439.10 KFM59909.1 - 0.083 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFM59909.1 - 0.088 12.7 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase JmjC PF02373.22 KFM59910.1 - 2.3e-25 89.2 0.1 6.1e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KFM59910.1 - 2.7e-19 69.9 0.1 1e-18 68.0 0.1 1.9 1 1 0 1 1 1 1 Cupin-like domain SR-25 PF10500.9 KFM59910.1 - 0.0071 16.0 15.0 0.01 15.5 15.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Ribosomal_S18 PF01084.20 KFM59911.1 - 3.4e-11 43.2 0.8 9.3e-11 41.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S18 RecR PF02132.15 KFM59911.1 - 0.012 15.1 0.3 0.012 15.1 0.3 1.7 2 0 0 2 2 2 0 RecR protein Laps PF10169.9 KFM59911.1 - 0.024 15.2 0.6 0.04 14.5 0.6 1.3 1 0 0 1 1 1 0 Learning-associated protein Nuc_sug_transp PF04142.15 KFM59913.1 - 2.1e-114 381.9 18.4 2.4e-114 381.7 18.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFM59913.1 - 1.9e-08 34.6 29.6 6.7e-06 26.3 5.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFM59913.1 - 0.00012 21.4 17.6 0.00018 20.8 16.9 1.4 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 KFM59913.1 - 0.00049 19.2 8.8 0.00049 19.2 8.8 1.8 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 KFM59913.1 - 0.0022 17.7 14.7 0.03 13.9 15.2 2.2 1 1 1 2 2 2 1 Putative multidrug resistance efflux transporter GDA1_CD39 PF01150.17 KFM59916.1 - 6.5e-59 199.7 0.0 7.6e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KFM59916.1 - 0.046 13.2 0.0 0.79 9.1 0.0 2.1 1 1 1 2 2 2 0 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 KFM59917.1 - 8e-09 34.7 0.1 9.3e-09 34.4 0.1 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family rve PF00665.26 KFM59918.1 - 2.8e-21 75.9 0.1 4.1e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM59918.1 - 2.8e-11 43.3 0.6 5.4e-11 42.4 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KFM59918.1 - 4.5e-05 23.1 0.5 0.003 17.3 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KFM59918.1 - 0.00025 21.3 0.4 0.00045 20.5 0.4 1.4 1 0 0 1 1 1 1 DDE domain zf-H2C2 PF09337.10 KFM59918.1 - 0.0017 18.5 0.1 0.0044 17.2 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DDE_3 PF13358.6 KFM59918.1 - 0.044 13.5 0.6 0.073 12.8 0.6 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease PHD PF00628.29 KFM59920.1 - 6.6e-05 22.7 1.4 0.00016 21.5 1.4 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 KFM59920.1 - 0.00055 20.2 1.9 0.0015 18.8 1.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFM59920.1 - 0.002 17.8 1.6 0.0053 16.5 1.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger CP2 PF04516.15 KFM59920.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 CP2 transcription factor zf-RING_5 PF14634.6 KFM59920.1 - 0.025 14.6 4.0 0.095 12.7 4.0 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 KFM59920.1 - 0.059 13.7 4.1 0.06 13.7 2.3 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM59920.1 - 0.061 13.4 4.0 0.48 10.5 4.0 2.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFM59920.1 - 0.31 10.9 3.7 0.47 10.4 2.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFM59920.1 - 4.8 6.9 7.8 0.49 10.1 3.0 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFM59920.1 - 10 6.4 7.6 22 5.3 5.1 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING HTH_Tnp_Tc3_2 PF01498.18 KFM59921.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59921.1 - 7.4e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Trypsin PF00089.26 KFM59922.1 - 1.6e-50 172.0 0.0 2.4e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFM59922.1 - 8.2e-15 55.1 0.0 2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 KFM59922.1 - 8.4e-09 35.5 9.4 2.8e-08 33.8 9.4 2.0 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 KFM59922.1 - 0.0011 19.4 0.0 0.0052 17.1 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFM59922.1 - 0.0011 19.9 0.0 0.0024 18.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KFM59922.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Chymotrypsin family Peptidase-S1 DDE_3 PF13358.6 KFM59923.1 - 2.7e-16 59.6 0.1 3.1e-15 56.2 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59923.1 - 1.5e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Peptidase_M24 PF00557.24 KFM59924.1 - 5.6e-49 166.7 0.1 6.8e-49 166.4 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KFM59924.1 - 6.8e-22 77.5 7.8 1.6e-21 76.3 7.8 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KFM59924.1 - 9.2e-05 22.4 3.6 0.00027 20.9 3.6 1.9 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KFM59924.1 - 0.015 15.1 4.8 0.034 14.0 4.8 1.7 1 0 0 1 1 1 0 HIT zinc finger Sun2_CC2 PF18580.1 KFM59924.1 - 0.12 12.7 0.6 0.26 11.5 0.6 1.5 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 CUB PF00431.20 KFM59925.1 - 1.3e-87 289.4 0.2 2.4e-36 124.4 0.0 3.3 3 0 0 3 3 3 3 CUB domain Astacin PF01400.24 KFM59925.1 - 8.6e-73 244.0 0.0 1.3e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 KFM59925.1 - 1.3e-09 38.1 8.5 4.6e-09 36.3 8.5 2.0 1 0 0 1 1 1 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFM59925.1 - 7.8e-08 32.5 9.1 7.8e-08 32.5 9.1 2.5 3 0 0 3 3 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFM59925.1 - 6.1e-06 26.1 4.0 2.7e-05 24.0 1.5 3.1 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.27 KFM59925.1 - 0.0048 17.2 5.3 0.02 15.2 5.3 2.2 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFM59925.1 - 0.0049 17.5 3.6 0.0055 17.3 1.3 2.5 2 0 0 2 2 2 1 Human growth factor-like EGF CUB_2 PF02408.20 KFM59925.1 - 0.009 15.8 1.0 2.4 7.9 0.0 2.9 3 0 0 3 3 3 2 CUB-like domain Peptidase_M10 PF00413.24 KFM59925.1 - 0.016 15.1 1.3 1.2 9.0 0.7 2.4 1 1 1 2 2 2 0 Matrixin Reprolysin_4 PF13583.6 KFM59925.1 - 0.044 13.4 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Plasmod_Pvs28 PF06247.11 KFM59925.1 - 0.27 11.5 9.7 0.12 12.7 6.6 2.1 2 0 0 2 2 2 0 Pvs28 EGF domain CUB PF00431.20 KFM59926.1 - 2.6e-30 105.0 0.0 8.2e-28 96.9 0.0 2.0 2 0 0 2 2 2 2 CUB domain RNase_H2_suC PF08615.11 KFM59927.1 - 8.5e-17 61.6 0.4 3.8e-10 40.1 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Acylphosphatase PF00708.18 KFM59928.1 - 0.065 13.6 1.0 0.065 13.6 1.0 3.0 1 1 2 3 3 3 0 Acylphosphatase UDPG_MGDP_dh_C PF03720.15 KFM59928.1 - 0.77 10.2 7.6 0.15 12.5 2.4 2.5 1 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UPF0176_N PF17773.1 KFM59928.1 - 1.6 9.1 5.9 9.9 6.6 0.7 3.1 2 2 0 2 2 2 0 UPF0176 acylphosphatase like domain Golgin_A5 PF09787.9 KFM59928.1 - 3.4 7.0 45.3 0.71 9.3 17.0 2.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 CN_hydrolase PF00795.22 KFM59930.1 - 1.5e-12 47.5 0.0 3.4e-12 46.3 0.0 1.6 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase AAA_14 PF13173.6 KFM59932.1 - 0.006 16.6 0.1 0.018 15.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFM59932.1 - 0.0094 15.0 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.6 KFM59932.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFM59932.1 - 0.039 14.5 0.0 0.15 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFM59932.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 KFM59932.1 - 0.071 13.4 0.1 0.28 11.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 KFM59932.1 - 0.075 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 KFM59932.1 - 0.11 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFM59932.1 - 0.11 12.4 0.2 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KFM59932.1 - 0.18 12.1 0.0 0.42 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain MFS_1 PF07690.16 KFM59933.1 - 3.1e-41 141.5 30.0 7.9e-26 90.8 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFM59933.1 - 0.0006 18.8 18.0 0.056 12.3 0.3 4.0 1 1 2 3 3 3 2 MFS_1 like family ArAE_2_N PF10337.9 KFM59933.1 - 0.14 11.2 0.1 0.14 11.2 0.1 2.1 3 0 0 3 3 3 0 Putative ER transporter, 6TM, N-terminal RseC_MucC PF04246.12 KFM59933.1 - 0.19 11.6 2.7 0.28 11.1 0.0 2.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC EF-hand_6 PF13405.6 KFM59934.1 - 0.0028 17.5 0.5 0.0058 16.5 0.4 1.6 1 1 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFM59934.1 - 0.0038 17.7 0.0 0.0061 17.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair Sas10_Utp3 PF04000.15 KFM59935.1 - 1.1e-13 51.6 0.1 1.7e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family NdhS PF11623.8 KFM59935.1 - 0.099 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S SRP9-21 PF05486.12 KFM59936.1 - 2.8e-12 46.8 1.8 1.5e-10 41.3 1.8 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF4371 PF14291.6 KFM59937.1 - 7.3e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) CUE PF02845.16 KFM59938.1 - 8.4e-14 50.9 0.1 1.5e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 KFM59938.1 - 0.034 13.8 0.1 0.099 12.3 0.0 1.8 2 0 0 2 2 2 0 DMRTA motif TIP39 PF14980.6 KFM59938.1 - 0.044 13.7 0.4 0.11 12.4 0.2 1.8 2 0 0 2 2 2 0 TIP39 peptide FANCI_S1-cap PF14674.6 KFM59938.1 - 0.19 11.8 0.4 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 FANCI solenoid 1 cap ACOX PF01756.19 KFM59939.1 - 6e-48 162.8 0.0 9.6e-48 162.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KFM59939.1 - 1.4e-15 57.2 0.0 2.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFM59939.1 - 6.6e-06 26.4 0.0 0.027 14.7 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain MPP6 PF10175.9 KFM59940.1 - 6.5e-22 78.4 12.0 8.9e-22 78.0 12.0 1.2 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Sigma70_ECF PF07638.11 KFM59940.1 - 0.015 15.2 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 ECF sigma factor Chordopox_A20R PF05941.13 KFM59940.1 - 0.071 12.1 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A20R protein Utp14 PF04615.13 KFM59940.1 - 0.31 9.6 10.3 0.76 8.3 10.3 1.5 1 1 0 1 1 1 0 Utp14 protein ANAPC10 PF03256.16 KFM59942.1 - 7.4e-22 77.9 0.0 7.6e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Acyltransferase PF01553.21 KFM59943.1 - 1.8e-20 73.0 0.0 3.3e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase AGTRAP PF06396.11 KFM59943.1 - 1.5 8.6 3.5 0.73 9.6 0.3 1.9 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) HTH_Tnp_Tc3_2 PF01498.18 KFM59944.1 - 2.8e-09 37.1 2.3 5.2e-09 36.2 2.3 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM59944.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.7 1 1 0 1 1 1 0 DDE superfamily endonuclease Lig_chan PF00060.26 KFM59945.1 - 1.6e-53 180.5 0.2 2.5e-53 179.9 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 KFM59945.1 - 7.6e-51 173.3 0.0 1.5e-50 172.3 0.0 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFM59945.1 - 1.9e-41 140.8 0.0 4e-41 139.8 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM59945.1 - 9.6e-25 87.3 0.0 2.6e-24 85.9 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 AA_permease_2 PF13520.6 KFM59945.1 - 0.062 12.1 3.3 0.13 11.1 3.3 1.5 1 0 0 1 1 1 0 Amino acid permease TraI_2B PF18340.1 KFM59945.1 - 0.097 12.8 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain PHO4 PF01384.20 KFM59946.1 - 2.7e-33 115.4 0.4 3.9e-33 114.9 0.4 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF2062 PF09835.9 KFM59946.1 - 0.041 13.7 2.1 0.052 13.4 2.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) PHO4 PF01384.20 KFM59947.1 - 1.6e-31 109.6 3.4 1.7e-31 109.5 3.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family Guanylate_cyc PF00211.20 KFM59948.1 - 1.2e-11 44.6 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF997 PF06196.12 KFM59949.1 - 0.11 12.5 3.2 0.36 10.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Guanylate_cyc PF00211.20 KFM59950.1 - 1.1e-25 90.3 0.1 1.2e-25 90.2 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2185 PF09951.9 KFM59951.1 - 0.039 13.8 0.5 0.045 13.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) DUF2973 PF11189.8 KFM59951.1 - 0.1 12.7 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) 7TM_GPCR_Srx PF10328.9 KFM59951.1 - 0.11 12.1 0.8 0.11 12.1 0.8 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx TMEMspv1-c74-12 PF11044.8 KFM59951.1 - 0.85 9.6 4.5 0.92 9.5 4.5 1.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4519 PF15012.6 KFM59951.1 - 1.2 9.4 7.3 1.7 8.9 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) AC_N PF16214.5 KFM59952.1 - 1.2e-08 34.5 0.1 1.2e-08 34.5 0.1 1.0 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region Chordopox_A13L PF05961.11 KFM59952.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus A13L protein THAP PF05485.12 KFM59953.1 - 3.7e-16 59.8 5.5 4.2e-16 59.7 5.5 1.2 1 0 0 1 1 1 1 THAP domain I-set PF07679.16 KFM59954.1 - 2.3e-41 139.7 0.0 1.7e-17 63.2 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM59954.1 - 4e-41 139.5 0.5 5.4e-16 59.0 0.2 3.6 4 0 0 4 4 3 3 Immunoglobulin domain ig PF00047.25 KFM59954.1 - 6.7e-29 99.9 0.0 2.9e-11 43.4 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM59954.1 - 8.3e-26 90.1 0.0 1.5e-10 41.3 0.1 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM59954.1 - 2.5e-20 72.7 0.1 0.00014 22.0 0.0 5.4 3 2 1 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM59954.1 - 2.4e-09 36.6 0.0 0.096 12.3 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_5 PF16681.5 KFM59954.1 - 1.1e-06 29.0 0.0 0.13 12.6 0.0 4.0 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM59954.1 - 1.6e-05 24.9 2.7 0.00049 20.1 0.0 3.2 4 1 0 4 4 3 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM59954.1 - 0.00016 21.8 0.0 1.2 9.5 0.0 4.0 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFM59954.1 - 0.009 16.0 0.0 1 9.4 0.0 3.6 4 1 0 4 4 3 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFM59954.1 - 0.028 14.5 0.0 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF4834 PF16118.5 KFM59954.1 - 0.049 14.6 0.0 0.095 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-RRN7 PF11781.8 KFM59954.1 - 0.099 12.3 0.1 13 5.5 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 EphA2_TM PF14575.6 KFM59954.1 - 0.15 13.0 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KFM59954.1 - 0.21 11.2 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family PhoLip_ATPase_C PF16212.5 KFM59955.1 - 2.4e-09 37.3 15.0 2.8e-09 37.1 15.0 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal SLATT_4 PF18186.1 KFM59955.1 - 0.083 12.5 1.5 0.13 11.9 1.5 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 RHD_dimer PF16179.5 KFM59956.1 - 3.1e-11 43.2 0.0 5.6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain RAI1 PF08652.11 KFM59958.1 - 7.8e-18 64.4 0.0 1.2e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF4909 PF16253.5 KFM59958.1 - 0.01 15.7 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4909) Transposase_1 PF01359.18 KFM59959.1 - 4.8e-06 26.3 0.0 7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Transposase (partial DDE domain) Prefoldin_2 PF01920.20 KFM59962.1 - 7.4e-07 29.1 0.2 1.2e-06 28.4 0.2 1.4 1 1 0 1 1 1 1 Prefoldin subunit PIN_8 PF18476.1 KFM59962.1 - 0.02 14.8 0.2 0.022 14.6 0.2 1.0 1 0 0 1 1 1 0 PIN like domain Prefoldin PF02996.17 KFM59962.1 - 0.073 13.0 0.7 0.25 11.2 0.7 2.0 1 1 0 1 1 1 0 Prefoldin subunit Myb_DNA-binding PF00249.31 KFM59963.1 - 9.1e-14 51.4 3.9 4.2e-09 36.4 0.3 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM59963.1 - 1.9e-08 34.4 12.6 9.7e-07 28.9 0.4 5.1 2 1 2 4 4 4 2 Myb-like DNA-binding domain FYRC PF05965.14 KFM59963.1 - 0.076 13.2 0.3 1.3 9.2 0.0 3.4 3 0 0 3 3 3 0 F/Y rich C-terminus Pkinase PF00069.25 KFM59964.1 - 6.5e-47 160.1 0.1 5e-26 91.6 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM59964.1 - 1.7e-18 66.9 0.0 4.1e-16 59.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 KFM59964.1 - 0.0055 16.3 0.1 0.76 9.4 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KFM59964.1 - 0.0083 14.9 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM59964.1 - 0.024 14.6 0.0 0.08 12.9 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM59964.1 - 0.06 12.7 0.0 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ApoLp-III PF07464.11 KFM59964.1 - 0.092 12.8 0.1 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Thiolase_N PF00108.23 KFM59965.1 - 2.4e-22 79.5 0.0 1.9e-21 76.6 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFM59965.1 - 1.8e-12 47.0 0.1 6.3e-12 45.2 0.1 1.9 1 1 0 1 1 1 1 Thiolase, C-terminal domain SCP2 PF02036.17 KFM59965.1 - 1.9e-11 44.3 0.0 3.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Ketoacyl-synt_C PF02801.22 KFM59965.1 - 0.00059 19.8 0.1 0.16 12.0 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 KFM59965.1 - 0.00084 19.1 2.0 0.055 13.3 0.1 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KFM59965.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Alkyl_sulf_C PF14864.6 KFM59965.1 - 0.0022 18.3 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SpoVAD PF07451.11 KFM59965.1 - 0.004 15.9 0.1 0.013 14.2 0.1 1.7 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) RANK_CRD_2 PF18278.1 KFM59965.1 - 0.069 13.3 0.3 0.25 11.5 0.3 2.0 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 RhoGAP PF00620.27 KFM59966.1 - 1.2e-38 132.4 0.0 3.3e-38 130.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain TSC22 PF01166.18 KFM59966.1 - 0.00072 19.8 1.6 0.0021 18.3 1.6 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family C1_1 PF00130.22 KFM59966.1 - 0.0008 19.2 16.0 0.0018 18.2 16.0 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DS PF01916.17 KFM59968.1 - 7e-76 255.2 0.0 7.8e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DS PF01916.17 KFM59969.1 - 3.5e-16 59.3 0.0 4.1e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase SCAI PF12070.8 KFM59970.1 - 8.3e-63 213.1 12.7 1.1e-62 212.7 12.7 1.2 1 0 0 1 1 1 1 Protein SCAI SCAI PF12070.8 KFM59971.1 - 3.7e-106 356.1 0.0 4.6e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Protein SCAI Acyl_transf_3 PF01757.22 KFM59972.1 - 5.6e-25 88.1 44.0 5.6e-25 88.1 44.0 1.6 2 0 0 2 2 2 1 Acyltransferase family Apolipoprotein PF01442.18 KFM59974.1 - 1.9e-09 37.7 15.2 1.9e-09 37.7 15.2 2.4 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM59974.1 - 7.2e-07 29.3 4.2 0.0031 17.5 0.4 3.9 3 1 1 4 4 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 KFM59974.1 - 2.8e-05 23.9 16.8 0.064 13.1 0.8 4.0 2 1 2 4 4 3 3 CdvA-like coiled-coil domain DUF1664 PF07889.12 KFM59974.1 - 0.0004 20.4 19.7 0.023 14.8 9.5 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) ApoO PF09769.9 KFM59974.1 - 0.0006 19.8 7.5 0.21 11.5 3.2 3.5 2 1 1 3 3 3 1 Apolipoprotein O Phasin PF05597.11 KFM59974.1 - 0.0023 17.9 20.3 0.003 17.6 8.1 3.1 1 1 2 3 3 3 2 Poly(hydroxyalcanoate) granule associated protein (phasin) Phage_Mu_Gam PF07352.12 KFM59974.1 - 0.0056 16.6 9.8 1 9.2 0.6 3.4 3 1 1 4 4 4 2 Bacteriophage Mu Gam like protein DUF5082 PF16888.5 KFM59974.1 - 0.0086 16.3 14.8 0.42 10.9 10.4 2.9 2 1 1 3 3 2 1 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 KFM59974.1 - 0.011 15.9 16.7 0.023 14.9 6.0 3.2 3 1 1 4 4 3 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 KFM59974.1 - 0.014 15.5 24.2 0.3 11.2 4.4 4.1 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 KFM59974.1 - 0.02 12.9 11.4 0.0052 14.8 8.4 1.4 2 0 0 2 2 2 0 Prominin DUF1640 PF07798.11 KFM59974.1 - 0.032 14.3 19.0 0.035 14.2 14.7 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1640) CLZ PF16526.5 KFM59974.1 - 0.041 14.2 12.7 0.054 13.9 0.4 5.0 3 2 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Peptidase_S64 PF08192.11 KFM59974.1 - 0.052 12.0 9.9 0.14 10.7 9.9 1.6 1 1 0 1 1 1 0 Peptidase family S64 HSBP1 PF06825.12 KFM59974.1 - 0.054 13.4 8.0 29 4.6 0.0 5.0 3 2 3 6 6 6 0 Heat shock factor binding protein 1 CENP-K PF11802.8 KFM59974.1 - 0.071 12.7 10.2 0.12 11.9 10.2 1.3 1 0 0 1 1 1 0 Centromere-associated protein K ApoLp-III PF07464.11 KFM59974.1 - 0.12 12.5 22.4 0.67 10.0 12.5 3.0 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF4795 PF16043.5 KFM59974.1 - 0.17 11.5 20.5 0.43 10.1 16.7 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) Cache_3-Cache_2 PF17201.4 KFM59974.1 - 0.25 10.6 7.5 0.34 10.2 1.6 2.3 2 0 0 2 2 2 0 Cache 3/Cache 2 fusion domain Gp58 PF07902.11 KFM59974.1 - 0.31 9.3 8.7 0.55 8.5 8.7 1.4 1 0 0 1 1 1 0 gp58-like protein DUF4085 PF13315.6 KFM59974.1 - 0.35 10.5 4.5 0.55 9.8 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Fzo_mitofusin PF04799.13 KFM59974.1 - 0.48 10.0 19.2 0.38 10.3 2.8 3.1 3 1 1 4 4 3 0 fzo-like conserved region SF-assemblin PF06705.11 KFM59974.1 - 0.57 9.5 19.8 0.82 9.0 18.1 2.1 2 1 0 2 2 2 0 SF-assemblin/beta giardin Spectrin PF00435.21 KFM59974.1 - 0.58 10.7 9.2 8 7.0 1.2 3.3 2 1 1 3 3 3 0 Spectrin repeat DUF3584 PF12128.8 KFM59974.1 - 0.73 7.3 20.3 0.47 7.9 17.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) DNA_photolyase PF00875.18 KFM59974.1 - 0.85 9.6 7.0 1.4 8.9 0.7 3.3 3 1 0 3 3 3 0 DNA photolyase KxDL PF10241.9 KFM59974.1 - 1 9.7 9.9 31 4.9 2.8 4.1 2 1 2 4 4 4 0 Uncharacterized conserved protein WXG100 PF06013.12 KFM59974.1 - 1 9.6 14.0 24 5.3 0.1 4.8 2 1 2 5 5 5 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 KFM59974.1 - 1.1 9.8 18.3 15 6.1 3.3 5.1 3 1 2 5 5 4 0 Nucleopolyhedrovirus P10 protein LPD37 PF18853.1 KFM59974.1 - 1.2 8.6 6.2 1.3 8.5 4.6 1.8 1 1 0 1 1 1 0 Large polyvalent protein associated domain 37 T3SS_needle_F PF09392.10 KFM59974.1 - 1.3 9.3 9.1 13 6.1 0.2 4.4 4 0 0 4 4 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Baculo_p24 PF05073.12 KFM59974.1 - 1.3 8.7 8.4 9.5 6.0 6.5 2.7 2 1 0 2 2 2 0 Baculovirus P24 capsid protein HalX PF08663.10 KFM59974.1 - 1.4 9.3 6.0 22 5.5 0.1 3.5 4 0 0 4 4 2 0 HalX domain Tweety PF04906.13 KFM59974.1 - 1.8 7.1 10.0 0.46 9.1 2.0 2.7 2 1 1 3 3 3 0 Tweety DUF148 PF02520.17 KFM59974.1 - 2 8.6 16.3 21 5.3 5.4 3.8 2 1 1 3 3 3 0 Domain of unknown function DUF148 DUF2443 PF10398.9 KFM59974.1 - 2 8.5 9.7 22 5.2 0.0 4.6 4 2 1 5 5 4 0 Protein of unknown function (DUF2443) Syntaxin PF00804.25 KFM59974.1 - 2.2 7.9 21.3 12 5.5 0.1 3.7 2 2 1 3 3 3 0 Syntaxin XhlA PF10779.9 KFM59974.1 - 3 8.1 10.6 4.2 7.7 1.5 4.2 2 1 2 4 4 4 0 Haemolysin XhlA BLOC1_2 PF10046.9 KFM59974.1 - 4.6 7.6 13.7 4.9 7.5 1.9 4.0 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1451 PF07295.11 KFM59974.1 - 4.9 7.2 11.0 23 5.0 5.8 2.7 1 1 2 3 3 3 0 Zinc-ribbon containing domain PIN_8 PF18476.1 KFM59974.1 - 5.5 6.8 13.7 2 8.2 3.9 2.6 2 1 1 3 3 3 0 PIN like domain Atg14 PF10186.9 KFM59974.1 - 5.6 5.9 12.1 2.2 7.3 8.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BshC PF10079.9 KFM59974.1 - 5.6 5.6 11.9 10 4.7 10.8 1.9 1 1 0 1 1 1 0 Bacillithiol biosynthesis BshC Exonuc_VII_L PF02601.15 KFM59974.1 - 6.2 6.3 13.5 40 3.6 13.5 2.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Occludin_ELL PF07303.13 KFM59974.1 - 6.3 7.6 10.4 11 6.8 1.2 3.6 2 1 1 3 3 3 0 Occludin homology domain YtxH PF12732.7 KFM59974.1 - 7.4 7.2 19.4 9.7 6.8 3.9 3.9 3 1 0 3 3 2 0 YtxH-like protein DUF4238 PF14022.6 KFM59974.1 - 7.9 5.9 7.3 16 4.9 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4238) RT_RNaseH_2 PF17919.1 KFM59975.1 - 1.3e-30 105.4 0.0 3.2e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM59975.1 - 3.4e-29 101.9 1.3 4.5e-29 101.5 0.3 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM59975.1 - 2.9e-27 95.0 0.0 1.3e-26 92.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM59975.1 - 3.8e-18 65.3 0.0 9.7e-18 64.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM59975.1 - 8e-17 61.5 0.0 2.4e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFM59975.1 - 3e-06 27.3 0.4 6.8e-06 26.2 0.4 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DDE_Tnp_IS240 PF13610.6 KFM59975.1 - 0.032 14.5 0.2 0.15 12.3 0.2 2.2 1 0 0 1 1 1 0 DDE domain BH4 PF02180.17 KFM59975.1 - 0.042 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Bcl-2 homology region 4 Acyl_transf_3 PF01757.22 KFM59976.1 - 9e-28 97.3 45.6 1.7e-27 96.4 45.6 1.4 1 0 0 1 1 1 1 Acyltransferase family DUF4371 PF14291.6 KFM59979.1 - 7.5e-05 22.5 0.0 7.7e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) zf-H2C2_2 PF13465.6 KFM59981.1 - 3.3e-30 103.1 22.4 2.2e-08 34.1 0.5 5.9 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM59981.1 - 4.4e-24 83.5 33.3 7.7e-07 29.2 1.6 5.4 6 0 0 6 6 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM59981.1 - 1.3e-22 78.5 21.0 3.2e-05 24.4 0.6 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KFM59981.1 - 7.3e-14 51.6 16.1 0.021 15.2 0.8 5.9 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM59981.1 - 6.3e-09 35.9 11.0 0.1 12.9 0.2 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM59981.1 - 1.3e-08 34.6 21.4 0.0038 17.2 1.7 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM59981.1 - 1.1e-05 25.7 16.3 0.51 10.7 1.1 4.6 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM59981.1 - 1.7e-05 24.4 26.1 0.18 11.6 0.4 4.9 5 0 0 5 5 4 4 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 KFM59981.1 - 2.8e-05 24.1 7.9 0.01 15.9 1.2 3.6 3 0 0 3 3 3 1 Zinc ribbon domain zf_UBZ PF18439.1 KFM59981.1 - 3.9e-05 23.1 6.1 2.7 7.7 0.0 4.7 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFM59981.1 - 4.1e-05 23.2 13.8 0.18 11.6 0.4 4.6 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-BED PF02892.15 KFM59981.1 - 8.1e-05 22.6 19.6 0.31 11.1 1.0 4.6 1 1 3 4 4 4 3 BED zinc finger zf-Di19 PF05605.12 KFM59981.1 - 0.00021 21.5 15.2 0.00039 20.6 1.6 3.9 4 0 0 4 4 3 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 KFM59981.1 - 0.001 19.8 8.0 0.13 13.1 1.3 2.3 2 0 0 2 2 2 2 zinc-ribbon family zf-C2H2_3rep PF18868.1 KFM59981.1 - 0.0018 18.9 8.7 0.0053 17.4 4.5 3.1 2 1 1 3 3 2 1 Zinc finger C2H2-type, 3 repeats Zf_RING PF16744.5 KFM59981.1 - 0.0033 17.5 6.8 6 7.1 0.1 4.1 1 1 3 4 4 4 0 KIAA1045 RING finger zf-C2HE PF16278.5 KFM59981.1 - 0.005 17.3 18.2 0.94 10.0 2.0 4.5 1 1 3 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger QueF PF14489.6 KFM59981.1 - 0.021 15.0 0.1 17 5.6 0.0 4.0 4 1 1 5 5 4 0 QueF-like protein zf-LYAR PF08790.11 KFM59981.1 - 0.026 14.4 15.2 4.1 7.4 0.2 4.8 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 KFM59981.1 - 0.078 13.1 7.2 34 4.7 0.1 4.2 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.19 KFM59981.1 - 0.095 12.7 7.9 2.1 8.4 1.0 2.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-UBP PF02148.19 KFM59981.1 - 0.096 13.0 12.1 0.48 10.8 5.0 3.4 1 1 2 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein LIM PF00412.22 KFM59981.1 - 0.1 12.9 13.2 3.6 7.9 3.2 4.1 1 1 1 3 3 3 0 LIM domain Prok-RING_1 PF14446.6 KFM59981.1 - 0.11 12.4 10.9 20 5.2 0.1 4.4 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 HNH_5 PF14279.6 KFM59981.1 - 0.35 10.8 7.4 14 5.7 0.7 4.3 3 1 0 3 3 3 0 HNH endonuclease zf-AN1 PF01428.16 KFM59981.1 - 0.42 10.8 12.2 25 5.1 0.1 4.5 4 0 0 4 4 4 0 AN1-like Zinc finger C1_1 PF00130.22 KFM59981.1 - 0.59 10.1 10.7 4.6 7.2 1.2 3.4 1 1 3 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Vps36-NZF-N PF16988.5 KFM59981.1 - 0.59 9.6 5.0 2.4 7.6 0.5 2.7 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PyrI_C PF02748.15 KFM59981.1 - 0.62 10.0 11.0 6.3 6.8 0.1 4.0 1 1 3 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Dof PF02701.15 KFM59981.1 - 2.6 8.3 11.3 12 6.2 0.3 4.0 1 1 2 3 3 3 0 Dof domain, zinc finger DZR PF12773.7 KFM59981.1 - 2.7 8.1 12.2 3.3e+02 1.4 12.0 3.1 1 1 0 1 1 1 0 Double zinc ribbon Elf1 PF05129.13 KFM59981.1 - 2.7 8.1 14.0 2.3 8.3 3.9 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HalOD2 PF18547.1 KFM59981.1 - 3.6 7.6 5.8 7.9 6.5 0.4 2.6 2 1 0 2 2 2 0 Halobacterial output domain 2 zf-trcl PF13451.6 KFM59981.1 - 3.8 7.5 13.4 40 4.2 0.6 4.1 4 0 0 4 4 4 0 Probable zinc-ribbon domain Rpr2 PF04032.16 KFM59981.1 - 4.4 7.6 11.2 66 3.9 0.4 3.2 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF629 PF04780.12 KFM59981.1 - 5.2 5.5 8.7 6.5 5.2 1.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF629) Actin_micro PF17003.5 KFM59981.1 - 5.4 6.1 11.3 59 2.7 8.7 3.0 1 1 1 2 2 2 0 Putative actin-like family zf-CHCC PF10276.9 KFM59981.1 - 5.5 7.1 6.5 93 3.2 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger domain Zn-C2H2_12 PF18112.1 KFM59981.1 - 5.5 7.6 8.2 32 5.1 0.2 3.8 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain FYVE PF01363.21 KFM59981.1 - 5.8 7.1 14.4 2.2e+03 -1.1 14.4 2.8 1 1 0 1 1 1 0 FYVE zinc finger Cript PF10235.9 KFM59981.1 - 7.5 7.2 15.2 8.1 7.1 3.7 3.4 1 1 2 3 3 3 0 Microtubule-associated protein CRIPT MIT_C PF16565.5 KFM59983.1 - 7.4e-56 188.1 3.3 1.4e-55 187.2 3.3 1.4 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT MIT PF04212.18 KFM59983.1 - 6.3e-15 55.0 0.1 2.3e-14 53.2 0.1 2.0 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF4456 PF14644.6 KFM59983.1 - 0.63 9.7 4.1 0.55 9.9 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) DDE_3 PF13358.6 KFM59984.1 - 1.7e-14 53.8 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease 53-BP1_Tudor PF09038.10 KFM59986.1 - 2e-16 60.0 0.0 4.1e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor DUF4537 PF15057.6 KFM59986.1 - 9.9e-10 38.5 0.0 4e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 KFM59986.1 - 1.9e-08 34.0 0.1 3e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Tudor_2 PF18104.1 KFM59986.1 - 3e-07 30.0 0.1 7e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 KFM59986.1 - 3.4e-05 23.5 0.1 0.011 15.4 0.0 2.7 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 DUF4772 PF15997.5 KFM59986.1 - 0.00091 19.8 0.2 0.037 14.6 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4772) YlaC PF10777.9 KFM59989.1 - 0.017 15.0 0.4 0.02 14.8 0.4 1.1 1 0 0 1 1 1 0 Inner membrane protein YlaC Hum_adeno_E3A PF05393.11 KFM59989.1 - 0.14 12.1 2.6 0.17 11.9 2.6 1.3 1 1 0 1 1 1 0 Human adenovirus early E3A glycoprotein His_Phos_2 PF00328.22 KFM59990.1 - 2.4e-06 27.2 0.1 3.8e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_M13 PF01431.21 KFM59993.1 - 3.6e-15 56.1 0.0 3.8e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM59994.1 - 3e-25 89.7 0.5 3.4e-25 89.6 0.5 1.0 1 0 0 1 1 1 1 Peptidase family M13 Tfb5 PF06331.12 KFM59995.1 - 0.062 13.3 0.0 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 HTH_Tnp_Tc3_2 PF01498.18 KFM59997.1 - 0.095 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM59998.1 - 3e-16 59.4 3.1 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM59998.1 - 1.1e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM59999.1 - 9.4e-14 51.4 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM59999.1 - 3.2e-11 43.3 0.5 7.7e-11 42.1 0.5 1.6 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM60000.1 - 3e-12 46.6 1.0 7.8e-12 45.3 1.0 1.7 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM60001.1 - 9.1e-16 57.9 2.2 9.1e-16 57.9 2.2 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60001.1 - 1.5e-13 50.7 0.0 4.3e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60002.1 - 3e-15 56.2 1.5 3e-15 56.2 1.5 1.7 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM60002.1 - 0.00017 22.1 9.4 0.00022 21.8 2.3 2.5 2 1 0 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM60003.1 - 1.9e-08 34.4 0.0 2e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM60004.1 - 2.5e-16 59.7 2.8 5e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60004.1 - 1e-13 51.2 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60004.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60004.1 - 0.0023 17.7 0.6 0.0068 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60004.1 - 0.025 14.7 0.4 0.081 13.1 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM60004.1 - 1.8 9.2 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM60005.1 - 4.1e-16 59.1 0.1 6.6e-15 55.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60005.1 - 7.9e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM60005.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM60005.1 - 0.002 17.9 0.1 0.12 12.2 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60005.1 - 0.014 15.5 0.1 0.065 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM60005.1 - 0.033 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM60006.1 - 6.9e-18 64.7 1.2 1.3e-17 63.8 1.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60006.1 - 6.4e-11 42.2 0.0 9.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM60006.1 - 0.00013 22.5 4.2 0.0025 18.4 0.2 2.9 3 0 0 3 3 3 1 Homeodomain-like domain Gly_rich PF12810.7 KFM60006.1 - 0.091 12.7 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycine rich protein HTH_Tnp_Tc3_2 PF01498.18 KFM60007.1 - 1.7e-13 50.6 0.4 3.4e-13 49.6 0.4 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60007.1 - 9.2e-10 38.4 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM60007.1 - 3.5e-05 24.3 1.5 3.5e-05 24.3 1.5 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60007.1 - 0.0018 18.4 0.6 0.053 13.7 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 KFM60007.1 - 0.024 14.3 0.2 0.072 12.7 0.2 1.8 1 0 0 1 1 1 0 Winged helix-turn helix MarR_2 PF12802.7 KFM60007.1 - 0.027 14.3 0.1 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_3 PF01381.22 KFM60007.1 - 0.039 14.0 0.5 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix DDE_3 PF13358.6 KFM60008.1 - 5.2e-12 45.8 0.0 7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60009.1 - 1.2e-16 60.7 1.9 4.4e-16 58.9 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60009.1 - 9.4e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60010.1 - 4.5e-16 58.9 3.5 5.6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60010.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60010.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60010.1 - 0.0027 17.4 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60010.1 - 0.029 14.5 0.4 0.09 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM60010.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM60011.1 - 1.5e-09 37.8 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60012.1 - 1.9e-19 69.6 3.6 5.2e-19 68.3 2.1 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60012.1 - 3.9e-16 59.1 0.0 2e-15 56.8 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM60012.1 - 2.4e-07 30.7 0.9 0.00011 22.2 0.0 2.7 3 0 0 3 3 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM60012.1 - 3.3e-07 30.8 2.0 3.3e-07 30.8 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60012.1 - 7.7e-07 29.1 1.7 0.0001 22.3 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM60012.1 - 2.3e-06 27.5 0.6 3.6e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KFM60012.1 - 5.6e-06 26.0 3.0 0.0001 22.0 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM60012.1 - 0.00011 22.0 0.6 0.0018 18.1 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM60012.1 - 0.001 19.0 0.4 0.015 15.2 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM60012.1 - 0.031 13.9 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM60012.1 - 0.05 13.7 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM60012.1 - 0.083 13.1 0.1 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 KFM60012.1 - 0.14 12.3 0.0 28 4.9 0.0 2.6 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM60012.1 - 0.25 11.2 3.9 1.4 8.8 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM60012.1 - 0.88 9.0 3.3 7.4 6.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc3_2 PF01498.18 KFM60013.1 - 2.2e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60013.1 - 8.5e-14 51.5 0.0 1.4e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60014.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60014.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60015.1 - 2.7e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60015.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60015.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60015.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60015.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain LRR_8 PF13855.6 KFM60016.1 - 1.1e-32 111.5 14.3 6.6e-14 51.4 0.3 4.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_5 PF13306.6 KFM60016.1 - 7.5e-16 58.2 8.7 7.8e-10 38.8 0.1 2.8 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) I-set PF07679.16 KFM60016.1 - 2.3e-14 53.2 0.0 5e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.7 KFM60016.1 - 1.2e-11 44.6 8.4 6.2e-06 26.5 0.7 4.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 KFM60016.1 - 1.9e-10 41.2 0.2 5.1e-10 39.8 0.2 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM60016.1 - 7.7e-08 32.4 0.1 1.7e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 KFM60016.1 - 5.6e-05 22.7 0.4 0.039 13.4 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KFM60016.1 - 0.00051 19.9 5.2 7.9 6.8 0.6 4.5 3 0 0 3 3 3 2 Leucine Rich repeat Ig_2 PF13895.6 KFM60016.1 - 0.00059 20.1 3.7 0.0013 19.0 0.9 2.6 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM60016.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin V-set domain LRR_1 PF00560.33 KFM60016.1 - 0.03 14.8 15.6 3.9 8.4 0.1 6.3 7 0 0 7 7 5 0 Leucine Rich Repeat HTH_Tnp_Tc3_2 PF01498.18 KFM60017.1 - 4.9e-16 58.7 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60017.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60017.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60017.1 - 0.0066 16.2 2.8 0.0075 16.0 0.6 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM60018.1 - 2.1e-17 63.1 1.4 4.3e-17 62.1 1.4 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60018.1 - 3.4e-15 56.1 0.0 5.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM60018.1 - 3.1e-05 24.5 7.6 7.6e-05 23.3 0.7 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_3 PF01381.22 KFM60018.1 - 0.016 15.2 0.3 0.66 10.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_23 PF13384.6 KFM60018.1 - 0.097 12.5 1.1 3 7.7 0.0 3.0 2 0 0 2 2 2 0 Homeodomain-like domain PPO1_DWL PF12142.8 KFM60018.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Apolipoprotein PF01442.18 KFM60019.1 - 0.0076 16.2 5.8 0.02 14.8 6.1 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Tnp_22_trimer PF17489.2 KFM60019.1 - 0.008 16.1 6.8 2.1 8.4 0.1 3.9 3 2 1 4 4 4 2 L1 transposable element trimerization domain FlaC_arch PF05377.11 KFM60019.1 - 0.013 15.9 1.4 0.013 15.9 1.4 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 KFM60019.1 - 0.02 15.1 3.4 0.093 13.0 3.3 2.2 1 1 0 1 1 1 0 ABC transporter C-terminal domain Zw10 PF06248.13 KFM60019.1 - 0.037 12.6 1.5 0.047 12.3 1.5 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF489 PF04356.12 KFM60019.1 - 0.038 14.0 0.5 0.049 13.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Fib_alpha PF08702.10 KFM60019.1 - 0.048 13.8 3.3 0.087 13.0 2.9 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 KFM60019.1 - 0.052 13.6 7.4 0.83 9.7 6.1 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 KFM60019.1 - 0.061 13.4 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 KFM60019.1 - 0.094 12.3 5.2 0.3 10.6 5.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF5446 PF17522.2 KFM60019.1 - 0.1 12.8 0.3 0.1 12.8 0.3 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5446) XhlA PF10779.9 KFM60019.1 - 0.1 12.8 0.4 0.26 11.5 0.3 1.8 1 1 0 1 1 1 0 Haemolysin XhlA Prominin PF05478.11 KFM60019.1 - 0.15 10.0 2.3 0.17 9.8 2.3 1.0 1 0 0 1 1 1 0 Prominin DUF842 PF05811.13 KFM60019.1 - 0.15 11.8 4.7 0.49 10.1 4.7 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Mis12 PF05859.12 KFM60019.1 - 0.16 12.1 1.9 0.24 11.5 0.4 1.8 1 1 1 2 2 2 0 Mis12 protein DUF1664 PF07889.12 KFM60019.1 - 0.47 10.5 5.3 1.2 9.2 4.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phasin PF05597.11 KFM60019.1 - 0.48 10.4 8.1 0.27 11.2 2.8 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TMF_TATA_bd PF12325.8 KFM60019.1 - 1.2 9.4 8.5 1.6 9.0 8.5 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF5082 PF16888.5 KFM60019.1 - 1.7 8.9 6.2 10 6.4 6.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 KFM60019.1 - 1.8 7.9 5.1 2.8 7.2 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KFM60019.1 - 1.8 7.3 7.7 2.1 7.1 7.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C2H2_jaz PF12171.8 KFM60020.1 - 2.4e-18 65.9 25.7 0.00011 22.3 6.3 4.6 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM60020.1 - 1.7e-17 63.1 24.0 3.4e-05 24.1 2.9 4.6 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFM60020.1 - 4.1e-12 46.3 19.6 0.0032 17.8 1.4 4.5 2 2 2 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM60020.1 - 1.2e-09 38.2 16.8 0.088 13.7 0.9 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM60020.1 - 9.9e-08 32.0 22.3 0.0086 16.5 2.3 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type PyocinActivator PF11112.8 KFM60020.1 - 0.098 12.8 0.5 0.39 10.9 0.1 2.2 2 0 0 2 2 2 0 Pyocin activator protein PrtN Zn-ribbon_8 PF09723.10 KFM60020.1 - 0.18 11.9 6.3 9 6.5 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain zf-LYAR PF08790.11 KFM60020.1 - 0.24 11.4 18.8 0.56 10.2 2.5 4.7 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFM60020.1 - 0.7 9.5 5.3 24 4.6 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger CbiG_C PF01890.16 KFM60023.1 - 0.096 13.3 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus PTS_2-RNA PF01885.16 KFM60024.1 - 8.1e-60 202.0 0.0 9.2e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Tektin PF03148.14 KFM60025.1 - 8.7e-45 153.1 17.7 1.1e-44 152.8 17.7 1.1 1 0 0 1 1 1 1 Tektin family SesA PF17107.5 KFM60025.1 - 0.00022 21.4 5.4 1.5 9.0 0.1 3.3 2 1 1 3 3 3 3 N-terminal domain on NACHT_NTPase and P-loop NTPases Fib_alpha PF08702.10 KFM60025.1 - 0.043 14.0 12.0 0.031 14.5 6.6 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 KFM60025.1 - 0.053 13.8 14.4 0.36 11.0 0.9 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Cob_adeno_trans PF01923.18 KFM60025.1 - 0.22 11.6 4.0 0.74 9.9 0.3 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Baculo_p24 PF05073.12 KFM60025.1 - 0.27 11.0 5.4 6.6 6.5 0.2 2.5 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Rx_N PF18052.1 KFM60025.1 - 0.36 11.1 13.2 9.6 6.6 0.6 3.3 2 1 1 3 3 3 0 Rx N-terminal domain Atg14 PF10186.9 KFM60025.1 - 0.59 9.2 14.2 0.54 9.3 5.2 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4164 PF13747.6 KFM60025.1 - 0.75 10.1 15.3 0.21 11.9 5.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Golgin_A5 PF09787.9 KFM60025.1 - 1 8.8 18.1 0.91 8.9 8.4 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 KFM60025.1 - 1.5 8.9 13.9 8 6.5 6.6 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein YojJ PF10372.9 KFM60025.1 - 1.7 8.8 4.2 8.9 6.5 0.2 2.7 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF1664 PF07889.12 KFM60025.1 - 1.7 8.7 8.7 3.9 7.5 1.5 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Prefoldin PF02996.17 KFM60025.1 - 2 8.3 8.8 7 6.6 1.0 3.0 2 1 1 3 3 3 0 Prefoldin subunit DUF883 PF05957.13 KFM60025.1 - 5.1 7.8 10.6 1 10.0 0.2 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) JIP_LZII PF16471.5 KFM60025.1 - 5.6 7.2 12.6 2 8.7 1.4 2.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 KFM60025.1 - 6 7.6 9.2 4.4 8.0 0.8 2.7 2 1 0 2 2 2 0 SlyX RasGAP_C PF03836.15 KFM60025.1 - 7.8 6.6 11.3 13 5.9 0.6 2.4 1 1 1 2 2 2 0 RasGAP C-terminus Tektin PF03148.14 KFM60026.1 - 4.5e-13 48.7 6.9 5.2e-13 48.5 6.9 1.0 1 0 0 1 1 1 1 Tektin family Apolipoprotein PF01442.18 KFM60026.1 - 0.00011 22.1 0.3 0.00016 21.6 0.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain APG17 PF04108.12 KFM60026.1 - 0.014 14.5 1.5 0.016 14.3 1.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 RRF PF01765.19 KFM60026.1 - 0.028 14.4 0.3 0.041 13.8 0.3 1.3 1 1 0 1 1 1 0 Ribosome recycling factor Prominin PF05478.11 KFM60026.1 - 0.034 12.1 0.6 0.037 12.0 0.6 1.0 1 0 0 1 1 1 0 Prominin DUF4665 PF15679.5 KFM60026.1 - 0.038 14.6 1.3 0.12 13.0 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) ApoLp-III PF07464.11 KFM60026.1 - 0.074 13.1 3.5 0.28 11.3 3.3 1.8 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 KFM60026.1 - 0.09 12.8 1.4 0.17 11.9 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GP41 PF00517.17 KFM60026.1 - 0.11 12.5 2.7 0.12 12.2 2.7 1.2 1 0 0 1 1 1 0 Retroviral envelope protein DUF948 PF06103.11 KFM60026.1 - 0.21 11.8 4.2 8.1 6.8 4.1 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HTH_Tnp_Tc3_2 PF01498.18 KFM60027.1 - 5e-14 52.3 1.5 9.7e-14 51.4 1.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60027.1 - 6.4e-14 51.9 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease RNA_pol_I_A49 PF06870.12 KFM60028.1 - 0.19 10.5 0.0 0.19 10.5 0.0 1.0 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor HTH_Tnp_Tc3_2 PF01498.18 KFM60029.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60029.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Homeodomain PF00046.29 KFM60030.1 - 1.6e-24 85.5 4.5 3.9e-24 84.3 4.5 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM60030.1 - 0.0015 18.3 0.1 0.004 17.0 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain HBM PF16591.5 KFM60030.1 - 0.004 16.6 0.4 0.0067 15.9 0.4 1.2 1 0 0 1 1 1 1 Helical bimodular sensor domain HTH_Tnp_Tc3_2 PF01498.18 KFM60031.1 - 2.2e-16 59.8 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60031.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Astacin PF01400.24 KFM60032.1 - 1.3e-56 191.2 2.3 1.8e-56 190.8 2.3 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 KFM60032.1 - 3.4e-07 30.6 0.0 7.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 CUB domain Peptidase_M10 PF00413.24 KFM60032.1 - 0.00015 21.6 0.6 0.032 14.1 0.1 2.3 1 1 1 2 2 2 2 Matrixin Reprolysin_4 PF13583.6 KFM60032.1 - 0.017 14.8 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KFM60032.1 - 0.036 13.0 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.8 KFM60032.1 - 0.14 11.8 0.3 0.41 10.2 0.1 1.8 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase TM2 PF05154.16 KFM60033.1 - 8.2e-15 54.9 9.2 8.2e-15 54.9 9.2 1.9 2 0 0 2 2 2 1 TM2 domain Claudin_2 PF13903.6 KFM60034.1 - 3.8e-22 79.0 14.2 5.4e-22 78.5 14.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFM60034.1 - 3.1e-05 23.9 12.5 0.0011 18.8 12.5 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 KFM60034.1 - 0.00041 19.9 17.7 0.061 12.8 17.7 2.2 1 1 0 1 1 1 1 Clc-like TAF1_subA PF14929.6 KFM60035.1 - 9.9e-32 110.8 5.8 2e-31 109.8 5.8 1.4 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A Ribosomal_L28e PF01778.17 KFM60036.1 - 4.5e-30 104.7 2.0 5.1e-30 104.6 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family I-set PF07679.16 KFM60038.1 - 1.4e-38 130.8 0.0 5e-17 61.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM60038.1 - 4.8e-35 120.0 0.1 2e-16 60.3 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM60038.1 - 1.8e-19 69.7 0.4 3.7e-07 30.2 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM60038.1 - 1.6e-16 60.4 1.0 7.6e-07 29.3 0.0 4.5 3 2 0 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM60038.1 - 1.7e-16 60.3 0.1 3.2e-06 27.4 0.0 4.2 4 1 0 4 4 4 3 Immunoglobulin domain C1-set PF07654.15 KFM60038.1 - 1.6e-06 28.4 0.4 0.0036 17.6 0.0 4.3 5 0 0 5 5 5 1 Immunoglobulin C1-set domain C2-set_2 PF08205.12 KFM60038.1 - 3.9e-06 26.8 0.0 0.00014 21.8 0.0 2.9 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM60038.1 - 4.4e-06 26.2 0.0 0.011 15.3 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain C2-set PF05790.15 KFM60038.1 - 0.00017 21.7 0.1 0.92 9.7 0.0 3.8 3 1 1 4 4 4 2 Immunoglobulin C2-set domain Ig_4 PF16680.5 KFM60038.1 - 0.0012 19.0 0.2 2.5 8.4 0.1 3.6 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Chordopox_A13L PF05961.11 KFM60038.1 - 0.19 12.0 0.5 0.39 11.0 0.5 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DDE_3 PF13358.6 KFM60040.1 - 1.5e-10 41.0 0.0 2.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_1 PF00001.21 KFM60041.1 - 7.5e-72 241.8 12.6 7.5e-72 241.8 12.6 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM60041.1 - 3.2e-15 56.2 10.9 6e-15 55.3 10.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM60041.1 - 7.1e-05 22.6 20.5 7.1e-05 22.6 20.5 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx RVT_1 PF00078.27 KFM60042.1 - 3.2e-16 59.5 0.0 3.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A21 PF03566.13 KFM60043.1 - 2.2 6.4 6.6 2.6 6.2 6.6 1.0 1 0 0 1 1 1 0 Peptidase family A21 Big_10 PF17964.1 KFM60044.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig domain TIM PF00121.18 KFM60045.1 - 4.9e-33 114.5 0.0 5.5e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MFS_1 PF07690.16 KFM60046.1 - 1.7e-07 30.5 0.3 1.7e-07 30.5 0.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFM60047.1 - 5.5e-14 51.9 10.5 6.6e-14 51.6 10.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM60047.1 - 0.0013 17.6 5.1 0.25 10.1 1.3 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter VIT1 PF01988.19 KFM60047.1 - 0.074 12.9 2.5 0.11 12.4 2.5 1.4 1 0 0 1 1 1 0 VIT family MFS_1 PF07690.16 KFM60048.1 - 0.0035 16.3 0.0 0.0035 16.3 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HTH_Tnp_Tc3_2 PF01498.18 KFM60049.1 - 1.3e-15 57.4 2.1 1.9e-15 56.8 1.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60049.1 - 1.1e-13 51.2 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60049.1 - 2.1e-07 30.6 1.2 6.6e-07 29.0 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60049.1 - 0.0026 17.5 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60049.1 - 0.027 14.6 0.4 0.085 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM60049.1 - 0.05 14.2 1.0 0.05 14.2 1.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM60050.1 - 1.1e-18 67.3 2.4 2.6e-18 66.0 1.0 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60050.1 - 1.6e-14 53.9 0.0 1.5e-13 50.7 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM60050.1 - 3e-05 24.5 2.6 6.3e-05 23.5 1.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM60050.1 - 0.0012 18.7 0.1 0.0083 16.1 0.1 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM60050.1 - 0.0047 17.0 1.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 KFM60050.1 - 0.033 14.1 0.3 0.93 9.4 0.0 2.9 3 1 1 4 4 4 0 MarR family HTH_23 PF13384.6 KFM60050.1 - 0.05 13.4 1.6 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain CrgA PF06781.12 KFM60051.1 - 0.002 18.2 0.7 0.0031 17.6 0.5 1.4 1 1 0 1 1 1 1 Cell division protein CrgA TMEM154 PF15102.6 KFM60051.1 - 0.0059 16.5 0.3 0.0072 16.2 0.3 1.1 1 0 0 1 1 1 1 TMEM154 protein family ISK_Channel PF02060.15 KFM60051.1 - 0.032 13.9 0.1 0.068 12.9 0.0 1.5 2 0 0 2 2 2 0 Slow voltage-gated potassium channel DUF5305 PF17231.2 KFM60051.1 - 0.05 13.0 0.1 0.055 12.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) HhH-GPD PF00730.25 KFM60054.1 - 4.5e-12 46.4 0.2 1.3e-11 44.9 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein C2 PF00168.30 KFM60055.1 - 7.5e-21 74.4 0.0 9.3e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 C2 domain DUF4371 PF14291.6 KFM60056.1 - 8e-10 38.8 0.0 2.6e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM60056.1 - 0.0078 15.8 0.4 0.0078 15.8 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger C2H2-type Dimer_Tnp_hAT PF05699.14 KFM60056.1 - 0.099 12.4 0.4 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region HTH_Tnp_Tc3_2 PF01498.18 KFM60057.1 - 5.2e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60057.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60057.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60057.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60057.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM60058.1 - 9.6e-15 54.6 0.1 1.5e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60058.1 - 2.4e-05 24.1 0.0 0.0054 16.5 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60059.1 - 2e-10 40.8 0.6 4.5e-10 39.6 0.3 1.6 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 KFM60059.1 - 0.022 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Ribosomal_L21e PF01157.18 KFM60059.1 - 0.061 13.2 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L21e HTH_28 PF13518.6 KFM60059.1 - 0.11 12.6 0.0 2.6 8.2 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain Ig_3 PF13927.6 KFM60060.1 - 9.3e-16 58.2 0.0 2.6e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM60060.1 - 1.6e-15 56.9 0.0 4.3e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM60060.1 - 3.3e-13 49.6 0.0 7.3e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM60060.1 - 1.3e-12 47.8 0.0 6.8e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM60060.1 - 3.2e-12 46.6 0.1 2.3e-06 27.7 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM60060.1 - 2.7e-05 24.5 0.0 0.67 10.4 0.0 2.9 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM60060.1 - 3e-05 23.5 0.0 0.036 13.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 KFM60060.1 - 0.0021 18.3 0.1 4.4 7.6 0.0 2.9 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFM60060.1 - 0.0031 17.5 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 1 CD47 immunoglobulin-like domain Receptor_2B4 PF11465.8 KFM60060.1 - 0.0089 16.2 0.0 0.99 9.6 0.0 2.2 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 C1-set PF07654.15 KFM60060.1 - 0.045 14.1 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFM60060.1 - 0.047 13.7 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM60061.1 - 2.6e-14 53.2 1.0 4.9e-14 52.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60061.1 - 6.1e-14 52.0 0.0 7.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60062.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60062.1 - 8.6e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM60063.1 - 1.2e-10 41.3 0.0 1.3e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM60064.1 - 6e-16 58.5 0.1 6.5e-15 55.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60064.1 - 7.8e-16 58.1 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM60064.1 - 0.00077 20.0 1.5 0.00077 20.0 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM60064.1 - 0.0027 17.5 0.4 0.12 12.2 0.0 3.3 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60064.1 - 0.014 15.5 0.1 0.069 13.3 0.1 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM60064.1 - 0.037 14.0 2.6 0.037 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM60066.1 - 1.8e-15 56.9 0.8 3.4e-15 56.0 0.8 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM60066.1 - 1.7e-06 28.5 6.8 2.2e-06 28.2 2.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM60066.1 - 0.0082 16.0 0.1 0.88 9.5 0.0 2.4 2 0 0 2 2 2 1 MarR family PAX PF00292.18 KFM60066.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain HTH_23 PF13384.6 KFM60066.1 - 0.42 10.5 4.0 2.8 7.9 0.1 3.0 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.6 KFM60066.1 - 8.2 6.6 6.6 3.5 7.8 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Avl9 PF09794.9 KFM60067.1 - 1.6e-61 208.1 0.0 1.7e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KFM60067.1 - 8.4e-09 35.4 0.0 2.4e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 KFM60067.1 - 4.5e-08 33.7 0.0 5.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking zf-CCHH PF10283.9 KFM60067.1 - 0.032 14.2 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 PBZ domain DENN PF02141.21 KFM60067.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 DENN (AEX-3) domain Pkinase PF00069.25 KFM60069.1 - 1.7e-61 207.9 0.2 1.4e-60 204.9 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM60069.1 - 3.2e-34 118.4 0.0 3.7e-33 114.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM60069.1 - 0.001 18.4 0.1 0.0045 16.3 0.0 2.2 2 1 0 2 2 2 1 Kinase-like RRM_1 PF00076.22 KFM60070.1 - 8.9e-25 86.3 0.0 6.6e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM60070.1 - 0.00022 20.8 0.0 0.34 10.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM60070.1 - 0.00035 20.6 0.1 0.00035 20.6 0.1 2.2 3 0 0 3 3 3 1 RNA binding motif OB_RNB PF08206.11 KFM60070.1 - 0.058 13.1 0.4 0.39 10.4 0.2 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF936 PF06075.12 KFM60070.1 - 7.5 5.3 37.7 8.7 5.1 37.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FEZ PF07763.13 KFM60072.1 - 3e-94 315.3 16.3 4.8e-94 314.6 16.3 1.3 1 0 0 1 1 1 1 FEZ-like protein DUF5102 PF17104.5 KFM60072.1 - 1.3e-06 28.7 9.1 0.0052 16.9 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5102) PH_8 PF15409.6 KFM60073.1 - 1.2e-12 48.0 0.4 1.2e-12 48.0 0.4 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFM60073.1 - 2.3e-08 34.5 1.4 3.5e-08 33.9 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFM60073.1 - 0.018 15.4 7.3 0.19 12.1 3.7 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain Exonuc_VII_S PF02609.16 KFM60073.1 - 0.037 14.1 0.5 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 Exonuclease VII small subunit CENP-K PF11802.8 KFM60073.1 - 0.073 12.6 7.9 1.4 8.4 0.6 2.4 2 0 0 2 2 2 0 Centromere-associated protein K DUF4407 PF14362.6 KFM60073.1 - 0.12 11.7 2.7 1.8 7.8 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Helo_like_N PF17111.5 KFM60073.1 - 0.14 11.5 4.1 2 7.8 0.3 2.3 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins V_ATPase_I PF01496.19 KFM60073.1 - 2.6 5.8 6.1 1.2 7.0 2.7 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family V-SNARE PF05008.15 KFM60073.1 - 4 7.9 7.8 1.3 9.5 0.4 3.2 2 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus BLOC1_2 PF10046.9 KFM60073.1 - 4.9 7.5 6.8 26 5.2 1.0 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YlqD PF11068.8 KFM60073.1 - 9.4 6.6 11.0 23 5.4 3.1 2.7 2 0 0 2 2 2 0 YlqD protein ABC2_membrane_3 PF12698.7 KFM60075.1 - 1.7e-19 70.2 9.1 1.7e-19 70.1 9.1 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KFM60076.1 - 1.7e-23 83.6 0.0 3.7e-23 82.6 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFM60076.1 - 9.5e-12 45.3 0.3 9.3e-09 35.5 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM60076.1 - 0.076 12.4 0.0 4.1 6.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM60077.1 - 2.1e-16 59.9 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60077.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60078.1 - 7.2e-18 64.6 0.6 1.3e-17 63.8 0.6 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM60078.1 - 0.00036 21.1 3.7 0.0022 18.6 0.9 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM60078.1 - 0.00037 20.5 0.7 0.022 14.8 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_23 PF13384.6 KFM60078.1 - 0.0082 15.9 0.8 0.33 10.8 0.1 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60078.1 - 0.0088 16.1 0.9 0.34 11.1 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.18 KFM60078.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain MarR_2 PF12802.7 KFM60078.1 - 0.091 12.7 0.3 0.98 9.4 0.0 2.3 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.6 KFM60078.1 - 0.1 12.6 0.8 0.75 9.8 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM60078.1 - 0.11 12.0 1.2 2.7 7.6 0.0 2.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 KFM60078.1 - 0.15 12.5 0.3 10 6.6 0.2 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain TAFH PF07531.14 KFM60079.1 - 3.4e-28 97.6 0.3 9.8e-28 96.1 0.3 1.8 2 0 0 2 2 2 1 NHR1 homology to TAF NHR2 PF08788.11 KFM60079.1 - 6.4e-16 57.9 1.2 1.4e-15 56.8 1.2 1.6 1 0 0 1 1 1 1 NHR2 domain like zf-MYND PF01753.18 KFM60079.1 - 1.9e-07 31.1 16.0 3.1e-07 30.4 16.0 1.4 1 0 0 1 1 1 1 MYND finger TBX PF12598.8 KFM60079.1 - 0.027 15.2 0.8 0.027 15.2 0.8 2.9 3 0 0 3 3 3 0 T-box transcription factor DUF3731 PF12531.8 KFM60079.1 - 0.032 14.1 1.3 0.058 13.2 1.3 1.3 1 0 0 1 1 1 0 DNA-K related protein zf-C2H2 PF00096.26 KFM60082.1 - 1.1e-12 47.6 43.2 0.38 11.3 0.1 8.7 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60082.1 - 1.1e-06 29.0 44.4 0.91 10.5 0.8 8.6 8 0 0 8 8 8 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM60082.1 - 0.00025 20.7 0.2 0.00025 20.7 0.2 5.5 5 1 0 5 5 5 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFM60082.1 - 0.0013 19.1 1.1 0.0013 19.1 1.1 7.9 9 0 0 9 9 9 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM60082.1 - 0.0017 18.6 40.6 0.15 12.4 0.1 7.1 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM60082.1 - 0.14 12.6 0.1 0.14 12.6 0.1 7.0 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM60082.1 - 0.26 11.1 0.1 0.26 11.1 0.1 5.9 6 0 0 6 6 6 0 zinc-finger C2H2-type DUF4187 PF13821.6 KFM60082.1 - 0.29 10.9 12.3 3.9 7.3 0.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) AKAP95 PF04988.12 KFM60082.1 - 4.5 7.5 7.7 40 4.4 0.8 3.5 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFM60082.1 - 5.1 7.5 19.4 3 8.2 4.3 5.0 3 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) eIF2A PF08662.11 KFM60083.1 - 0.0027 17.6 0.1 0.44 10.4 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KFM60083.1 - 0.004 18.0 3.9 37 5.4 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KFM60083.1 - 0.011 15.8 0.0 0.05 13.7 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF276 PF03434.13 KFM60083.1 - 0.026 13.7 0.6 0.068 12.3 0.0 1.8 2 0 0 2 2 2 0 DUF276 GH-E PF14410.6 KFM60085.1 - 0.032 14.6 0.0 0.032 14.6 0.0 1.1 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues RP854 PF17460.2 KFM60085.1 - 0.16 11.7 2.8 0.15 11.8 2.8 1.0 1 0 0 1 1 1 0 Uncharacterized protein RP854 MG2 PF01835.19 KFM60087.1 - 0.00055 20.3 0.0 0.00096 19.6 0.0 1.4 1 0 0 1 1 1 1 MG2 domain A2M_BRD PF07703.14 KFM60087.1 - 0.12 12.7 0.0 0.75 10.1 0.0 2.2 2 1 0 2 2 2 0 Alpha-2-macroglobulin bait region domain MG4 PF17789.1 KFM60088.1 - 1.1e-10 41.5 0.0 2.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Macroglobulin domain MG4 SRA PF18491.1 KFM60088.1 - 0.089 12.9 0.0 0.089 12.9 0.0 1.3 1 1 0 1 1 1 0 SET and RING associated domain A2M_BRD PF07703.14 KFM60089.1 - 4e-21 75.8 0.1 5e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain TED_complement PF07678.14 KFM60091.1 - 1.4e-39 136.0 0.0 1.5e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 A-macroglobulin TED domain Pox_F15 PF04596.12 KFM60091.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus protein F15 TED_complement PF07678.14 KFM60092.1 - 5.3e-10 38.8 0.7 8.3e-10 38.2 0.7 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain DHHA2 PF02833.14 KFM60092.1 - 0.074 13.2 0.1 0.085 13.0 0.1 1.1 1 0 0 1 1 1 0 DHHA2 domain A2M_recep PF07677.14 KFM60093.1 - 0.013 16.2 0.0 0.014 16.1 0.0 1.0 1 0 0 1 1 1 0 A-macroglobulin receptor binding domain NTR PF01759.21 KFM60094.1 - 0.02 14.7 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 UNC-6/NTR/C345C module AMP-binding PF00501.28 KFM60095.1 - 5.3e-50 170.2 0.0 7e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM60095.1 - 8.7e-13 48.0 2.5 1.6e-12 47.1 2.5 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KFM60097.1 - 0.011 16.6 0.0 0.02 15.9 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Ion_trans PF00520.31 KFM60099.1 - 7e-65 218.7 12.1 4.6e-45 153.7 1.9 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KFM60099.1 - 0.0025 16.6 0.3 0.0025 16.6 0.3 2.7 2 1 1 3 3 3 2 Polycystin cation channel Lustrin_cystein PF14625.6 KFM60099.1 - 0.0029 18.0 0.3 0.0063 16.9 0.3 1.5 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain Ion_trans PF00520.31 KFM60100.1 - 1e-120 401.5 70.0 3.4e-53 180.4 18.5 4.1 3 1 1 4 4 4 4 Ion transport protein GPHH PF16905.5 KFM60100.1 - 1e-09 38.0 0.0 2.3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KFM60100.1 - 3.6e-06 25.9 62.6 0.00079 18.2 8.0 6.2 4 2 2 6 6 6 4 Polycystin cation channel Glyco_hydro_18 PF00704.28 KFM60101.1 - 3.1e-98 329.4 0.5 3.7e-98 329.1 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 KFM60101.1 - 6.3e-10 39.1 3.8 1.1e-09 38.3 3.8 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain RRM_1 PF00076.22 KFM60102.1 - 5e-41 138.4 1.6 2e-15 56.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM60102.1 - 2.9e-05 24.1 0.1 0.66 10.1 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM60102.1 - 0.00036 20.5 0.3 5.5 7.1 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFM60102.1 - 0.00048 19.7 0.0 0.0047 16.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFM60102.1 - 0.0023 18.0 0.0 0.37 10.9 0.0 3.0 2 1 1 3 3 3 1 Limkain b1 RRM_3 PF08777.11 KFM60102.1 - 0.0092 16.0 1.6 0.13 12.3 0.3 2.8 2 1 1 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 KFM60102.1 - 0.028 14.3 0.0 9.8 6.1 0.0 3.3 3 1 0 3 3 3 0 Occluded RNA-recognition motif Pdase_M17_N2 PF18295.1 KFM60102.1 - 0.15 12.3 0.2 0.38 11.0 0.0 1.7 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 BTG PF07742.12 KFM60104.1 - 4.1e-42 142.7 0.0 6.3e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 BTG family SCHIP-1 PF10148.9 KFM60105.1 - 1.5e-08 34.6 1.4 2.2e-08 34.0 1.4 1.3 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 EURL PF06937.11 KFM60105.1 - 0.00014 21.4 8.6 0.00019 20.9 8.4 1.4 1 1 0 1 1 1 1 EURL protein DUF5102 PF17104.5 KFM60105.1 - 0.00091 19.3 1.3 0.0011 19.1 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) FEZ PF07763.13 KFM60105.1 - 0.018 14.8 6.9 0.023 14.4 6.5 1.3 1 1 0 1 1 1 0 FEZ-like protein TBCC_N PF16752.5 KFM60105.1 - 0.068 13.6 10.4 0.03 14.8 7.1 2.1 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF226 PF02890.14 KFM60105.1 - 0.099 12.7 2.7 0.14 12.2 2.7 1.2 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 DUF4757 PF15949.5 KFM60105.1 - 0.43 11.0 3.1 0.61 10.5 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) FOXP-CC PF16159.5 KFM60105.1 - 8.8 7.0 8.7 6.6 7.4 2.6 2.8 1 1 2 3 3 3 0 FOXP coiled-coil domain HTH_Tnp_Tc3_2 PF01498.18 KFM60106.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60106.1 - 5.3e-14 52.2 0.0 9.2e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60106.1 - 1.7e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60106.1 - 0.0024 17.6 0.6 0.0069 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60106.1 - 1.7 9.3 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain THAP PF05485.12 KFM60107.1 - 5e-16 59.4 2.2 5e-16 59.4 2.2 3.0 2 0 0 2 2 2 1 THAP domain Tnp_P_element PF12017.8 KFM60107.1 - 2.4e-09 37.0 5.1 5.8e-09 35.7 5.1 1.7 1 0 0 1 1 1 1 Transposase protein HTH_Tnp_Tc3_2 PF01498.18 KFM60108.1 - 3.4e-28 97.7 18.7 8.2e-15 54.8 6.5 2.7 2 0 0 2 2 2 2 Transposase DUF4371 PF14291.6 KFM60108.1 - 5.2e-20 72.1 0.0 1.2e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DDE_3 PF13358.6 KFM60108.1 - 2.6e-15 56.4 1.0 5.8e-14 52.1 0.0 3.4 3 1 1 4 4 4 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM60108.1 - 5.2e-05 23.8 9.7 0.00072 20.1 1.5 4.2 4 0 0 4 4 4 2 Homeodomain-like domain HTH_23 PF13384.6 KFM60108.1 - 0.0013 18.4 2.2 0.53 10.2 0.0 3.9 4 0 0 4 4 4 1 Homeodomain-like domain HTH_29 PF13551.6 KFM60108.1 - 0.0097 15.9 5.5 0.16 12.0 0.2 3.4 3 0 0 3 3 3 1 Winged helix-turn helix HTH_33 PF13592.6 KFM60108.1 - 0.03 14.0 1.3 0.85 9.3 0.1 2.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 KFM60108.1 - 0.17 12.1 9.9 0.3 11.2 0.1 3.8 5 0 0 5 5 5 0 Helix-turn-helix domain RSS_P20 PF11757.8 KFM60108.1 - 0.24 11.9 0.1 0.24 11.9 0.1 2.3 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM60109.1 - 8.3e-35 118.9 13.7 1.2e-18 67.1 2.1 3.2 3 0 0 3 3 3 2 Transposase DDE_3 PF13358.6 KFM60109.1 - 9.6e-31 106.5 0.0 2.9e-15 56.3 0.0 2.9 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_23 PF13384.6 KFM60109.1 - 1.7e-10 40.4 9.1 4.1e-06 26.4 0.0 3.9 3 1 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 KFM60109.1 - 6e-09 35.9 7.9 0.0001 22.4 0.1 3.8 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_7 PF02796.15 KFM60109.1 - 2.1e-08 34.1 1.1 0.00025 21.0 0.0 3.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM60109.1 - 2e-07 30.9 5.5 6.8e-06 26.0 0.1 3.6 3 0 0 3 3 3 1 Winged helix-turn helix HTH_38 PF13936.6 KFM60109.1 - 2.6e-07 30.3 9.6 1.6e-06 27.7 0.2 4.1 4 1 0 4 4 4 2 Helix-turn-helix domain HTH_32 PF13565.6 KFM60109.1 - 7.7e-07 29.6 2.0 7.7e-07 29.6 2.0 4.4 4 1 1 5 5 4 2 Homeodomain-like domain MarR_2 PF12802.7 KFM60109.1 - 0.0025 17.7 4.0 0.0042 16.9 0.0 3.1 3 1 1 4 4 4 1 MarR family HTH_Crp_2 PF13545.6 KFM60109.1 - 0.0033 17.4 2.4 0.034 14.1 0.0 3.3 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 KFM60109.1 - 0.032 14.3 2.1 1.4 9.0 0.0 3.7 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_33 PF13592.6 KFM60109.1 - 0.093 12.4 1.4 9.6 5.9 0.1 3.0 3 0 0 3 3 3 0 Winged helix-turn helix CENP-B_N PF04218.13 KFM60109.1 - 0.1 12.2 0.5 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain GntR PF00392.21 KFM60109.1 - 0.11 12.1 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_Tnp_Tc3_1 PF11427.8 KFM60109.1 - 0.12 12.3 0.0 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Tc3 transposase PAX PF00292.18 KFM60109.1 - 0.2 11.6 0.8 0.75 9.7 0.0 2.3 3 0 0 3 3 3 0 'Paired box' domain HTH_30 PF13556.6 KFM60109.1 - 0.48 10.3 3.0 2.5 8.0 0.0 3.2 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DDE_Tnp_1_7 PF13843.6 KFM60110.1 - 2.1e-46 158.8 0.0 2.7e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 2OG-FeII_Oxy_2 PF13532.6 KFM60111.1 - 1.5e-22 80.8 0.0 2.5e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RE_NgoBV PF09564.10 KFM60111.1 - 0.063 12.7 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 NgoBV restriction endonuclease Ribosomal_L7Ae PF01248.26 KFM60112.1 - 1.3e-22 79.4 0.1 1.7e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFM60112.1 - 0.021 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 COG6 PF06419.11 KFM60113.1 - 2.2e-65 221.1 11.3 2.6e-65 220.8 11.3 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Sec34 PF04136.15 KFM60113.1 - 5.8e-05 23.0 2.3 5.8e-05 23.0 2.3 1.9 2 0 0 2 2 2 1 Sec34-like family PhaP_Bmeg PF09602.10 KFM60113.1 - 0.0096 15.9 4.6 0.016 15.2 3.2 2.0 1 1 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) COG2 PF06148.11 KFM60113.1 - 0.035 14.2 3.8 0.056 13.5 2.8 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 KFM60113.1 - 0.036 14.7 1.8 0.036 14.7 1.8 2.5 1 1 2 3 3 3 0 Initiation control protein YabA HMMR_N PF15905.5 KFM60113.1 - 0.054 13.0 9.7 0.11 11.9 9.7 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal COG6 PF06419.11 KFM60114.1 - 1.4e-129 433.2 0.8 1.6e-129 433.0 0.8 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RB_A PF01858.17 KFM60114.1 - 8.9e-05 22.4 0.5 8.9e-05 22.4 0.5 1.8 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain Fungal_trans_2 PF11951.8 KFM60114.1 - 0.064 12.1 1.7 0.062 12.1 0.4 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain Bacteriocin_II PF01721.18 KFM60118.1 - 0.39 10.9 1.9 0.66 10.1 0.8 1.9 2 0 0 2 2 2 0 Class II bacteriocin Methyltransf_34 PF11312.8 KFM60119.1 - 6.9e-08 32.1 0.0 9.9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase RICTOR_V PF14668.6 KFM60120.1 - 6.3e-27 93.6 0.4 1.6e-25 89.1 0.3 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 KFM60120.1 - 2.9e-10 40.5 0.2 1.1e-09 38.6 0.3 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KFM60121.1 - 7.9e-11 41.7 0.3 2.9e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain IMP2_N PF18590.1 KFM60121.1 - 0.025 15.1 0.1 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) N-terminal domain Phi-29_GP16_7 PF06720.11 KFM60121.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 MCM_N PF14551.6 KFM60121.1 - 0.092 13.3 0.1 0.98 10.0 0.0 2.5 3 0 0 3 3 3 0 MCM N-terminal domain RICTOR_N PF14664.6 KFM60122.1 - 2.7e-62 210.9 2.1 3.2e-62 210.7 2.1 1.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term O-FucT PF10250.9 KFM60123.1 - 4.1e-73 247.0 0.2 4.8e-73 246.8 0.2 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase UCH PF00443.29 KFM60124.1 - 1.6e-30 106.5 5.0 2.2e-30 106.0 5.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM60124.1 - 5.2e-16 59.1 15.4 3.4e-15 56.5 15.4 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PHF5 PF03660.14 KFM60124.1 - 0.56 10.4 4.8 0.11 12.7 0.8 1.8 2 0 0 2 2 2 0 PHF5-like protein CP2 PF04516.15 KFM60125.1 - 5.3e-68 228.8 0.1 8.3e-68 228.1 0.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFM60125.1 - 2.9e-13 49.4 0.0 7.1e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Catalase PF00199.19 KFM60125.1 - 0.006 15.7 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 1 Catalase Allantoicase PF03561.15 KFM60125.1 - 0.14 12.1 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Allantoicase repeat SAM_2 PF07647.17 KFM60125.1 - 0.17 12.0 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Prok-RING_4 PF14447.6 KFM60126.1 - 6.4e-06 25.9 3.2 6.4e-06 25.9 3.2 2.7 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFM60126.1 - 4.1e-05 23.4 5.9 4.1e-05 23.4 5.9 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFM60126.1 - 0.043 13.7 5.8 0.18 11.7 5.8 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein GAGA PF09237.11 KFM60126.1 - 0.049 13.4 0.7 0.13 12.1 0.7 1.7 1 0 0 1 1 1 0 GAGA factor PTH2 PF01981.16 KFM60128.1 - 1.5e-17 63.9 0.0 1.7e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Fz PF01392.22 KFM60129.1 - 4.1e-18 66.0 0.8 4.1e-18 66.0 0.8 2.3 2 0 0 2 2 2 1 Fz domain Ldl_recept_a PF00057.18 KFM60129.1 - 1.3e-17 63.6 36.5 3.5e-10 39.9 9.3 4.0 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A Trypsin PF00089.26 KFM60129.1 - 1.8e-13 50.9 0.0 4.3e-13 49.6 0.0 1.6 2 0 0 2 2 2 1 Trypsin SRCR_2 PF15494.6 KFM60129.1 - 6.4e-08 33.0 0.1 2.2e-07 31.3 0.1 1.9 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 KFM60129.1 - 2.3e-07 31.2 0.3 2.3e-07 31.2 0.3 2.2 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain PRKCSH-like PF12999.7 KFM60129.1 - 0.02 14.7 14.5 0.037 13.8 14.5 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Hepsin-SRCR PF09272.10 KFM60129.1 - 0.061 13.8 0.1 0.061 13.8 0.1 2.1 2 0 0 2 2 2 0 Hepsin, SRCR domain Sec16_C PF12931.7 KFM60130.1 - 9.4e-47 160.1 1.7 1.1e-46 159.9 0.1 1.8 1 1 1 2 2 2 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KFM60130.1 - 1.3e-09 38.6 0.0 6.1e-09 36.5 0.0 2.3 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region CCDC85 PF10226.9 KFM60130.1 - 0.064 12.9 0.0 0.064 12.9 0.0 2.0 2 0 0 2 2 2 0 CCDC85 family zf-LYAR PF08790.11 KFM60131.1 - 0.04 13.8 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C3HC4_3 PF13920.6 KFM60132.1 - 9.1e-07 28.7 13.3 1.1e-06 28.4 13.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM60132.1 - 0.0012 18.7 12.9 0.0018 18.1 12.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFM60132.1 - 0.0085 16.4 14.9 0.012 15.9 14.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM60132.1 - 0.02 14.7 14.5 0.033 14.0 14.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM60132.1 - 0.072 13.0 15.5 0.11 12.4 15.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM60132.1 - 0.24 11.4 13.9 0.39 10.7 13.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-piccolo PF05715.13 KFM60132.1 - 0.85 9.8 11.3 7 6.9 7.0 2.1 1 1 1 2 2 2 0 Piccolo Zn-finger Toxin_31 PF08119.11 KFM60132.1 - 2.2 8.1 10.7 0.41 10.4 7.3 1.6 1 1 0 1 1 1 0 Scorpion acidic alpha-KTx toxin family M_domain PF12938.7 KFM60133.1 - 4.4e-31 108.6 33.5 4.4e-31 108.6 33.5 4.1 4 0 0 4 4 4 1 M domain of GW182 RRM_1 PF00076.22 KFM60133.1 - 9.5e-06 25.4 0.0 2.8e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA PF00627.31 KFM60133.1 - 0.00013 21.8 0.2 0.00028 20.7 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RRM_occluded PF16842.5 KFM60133.1 - 0.029 14.2 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif UBA_2 PF08587.11 KFM60133.1 - 0.043 13.9 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) BAG PF02179.16 KFM60134.1 - 1.5e-10 41.3 0.6 3e-10 40.4 0.1 1.7 2 0 0 2 2 2 1 BAG domain Lung_7-TM_R PF06814.13 KFM60136.1 - 1e-86 290.9 9.0 1.2e-86 290.6 9.0 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 KFM60136.1 - 3.8e-07 29.8 16.6 5.7e-07 29.2 16.6 1.3 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain TatC PF00902.18 KFM60136.1 - 9 6.1 12.9 18 5.1 12.9 1.5 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) XK-related PF09815.9 KFM60138.1 - 1.6e-35 122.8 15.4 2e-35 122.5 15.4 1.1 1 0 0 1 1 1 1 XK-related protein DUF5316 PF17247.2 KFM60138.1 - 0.47 10.5 4.6 5.2 7.2 0.3 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5316) zf-H2C2_2 PF13465.6 KFM60140.1 - 5.9e-120 386.9 149.9 6.4e-08 32.7 0.5 20.2 20 0 0 20 20 20 19 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60140.1 - 1.2e-85 277.5 169.7 1.7e-05 25.0 1.1 19.2 19 0 0 19 19 19 19 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60140.1 - 2.4e-62 202.2 160.0 0.0017 19.0 1.1 19.2 19 0 0 19 19 19 19 C2H2-type zinc finger zf-met PF12874.7 KFM60140.1 - 1.7e-44 148.9 162.5 0.00049 20.4 1.3 19.7 20 0 0 20 20 20 19 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM60140.1 - 2.5e-17 62.4 148.1 0.015 15.3 2.4 20.1 19 2 0 19 19 19 12 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM60140.1 - 2.7e-17 62.5 75.3 0.044 13.8 0.2 18.4 11 4 8 19 19 19 8 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KFM60140.1 - 2.5e-11 43.5 126.3 0.76 10.1 1.5 19.4 19 0 0 19 19 19 11 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM60140.1 - 3.2e-06 26.9 83.0 2.8 7.9 0.3 17.3 19 0 0 19 19 19 5 zinc-finger of a C2HC-type BolA PF01722.18 KFM60140.1 - 3.1e-05 24.2 36.6 14 6.0 0.1 11.7 2 1 7 10 10 10 0 BolA-like protein zf-C2H2_11 PF16622.5 KFM60140.1 - 0.0063 16.2 0.2 0.0063 16.2 0.2 17.4 19 0 0 19 19 18 8 zinc-finger C2H2-type zf-MYST PF17772.1 KFM60140.1 - 0.0086 15.7 117.0 0.62 9.7 0.2 18.6 2 2 17 19 19 19 7 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFM60140.1 - 0.01 16.6 86.2 0.7 10.7 1.6 10.4 1 1 8 11 11 11 0 zinc-ribbon family Scramblase PF03803.15 KFM60140.1 - 0.013 14.8 23.3 0.052 12.8 4.2 4.0 1 1 1 3 3 3 0 Scramblase zf-C2H2_8 PF15909.5 KFM60140.1 - 0.036 14.4 93.8 0.07 13.4 1.9 9.3 1 1 7 9 9 8 0 C2H2-type zinc ribbon DZR PF12773.7 KFM60140.1 - 0.064 13.3 70.4 1.1e+03 -0.3 11.3 11.0 1 1 2 3 3 1 0 Double zinc ribbon zf_UBZ PF18439.1 KFM60140.1 - 0.092 12.4 82.1 4.1 7.1 0.1 18.3 19 0 0 19 19 19 0 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM60140.1 - 0.18 11.9 95.7 0.45 10.6 11.1 8.8 1 1 4 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM60140.1 - 0.19 11.9 81.4 13 6.0 0.3 18.3 19 0 0 19 19 19 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM60140.1 - 0.4 10.8 104.4 18 5.5 0.3 18.9 19 0 0 19 19 19 0 DBF zinc finger Amidohydro_1 PF01979.20 KFM60140.1 - 0.62 9.3 21.7 7.4 5.8 0.2 6.7 1 1 3 7 7 7 0 Amidohydrolase family Integrase_H2C2 PF17921.1 KFM60141.1 - 7.5e-11 42.0 0.4 9.3e-11 41.7 0.4 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM60141.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 H2C2 zinc finger Adeno_IVa2 PF02456.15 KFM60143.1 - 9.6e-07 27.9 0.1 1e-06 27.8 0.1 1.0 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_11 PF13086.6 KFM60143.1 - 0.00035 20.4 0.0 0.00037 20.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFM60143.1 - 0.0063 15.6 0.0 0.0068 15.5 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KFM60143.1 - 0.014 15.8 0.0 0.016 15.6 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 KFM60143.1 - 0.021 14.8 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ResIII PF04851.15 KFM60143.1 - 0.025 14.6 0.0 0.027 14.5 0.0 1.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KFM60143.1 - 0.027 14.4 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KFM60143.1 - 0.048 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 KFM60143.1 - 0.056 12.9 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 KFM60143.1 - 0.061 13.6 0.0 0.071 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KFM60143.1 - 0.073 12.8 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_7 PF12775.7 KFM60143.1 - 0.076 12.5 0.1 0.11 12.0 0.0 1.3 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KFM60143.1 - 0.1 13.0 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.18 KFM60143.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.19 KFM60143.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KFM60143.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KFM60143.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KFM60143.1 - 0.14 12.3 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFM60143.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KFM60143.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KFM60143.1 - 0.14 12.2 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain Endonuc-EcoRV PF09233.11 KFM60143.1 - 0.16 11.3 0.0 0.18 11.1 0.0 1.0 1 0 0 1 1 1 0 Restriction endonuclease EcoRV RNA12 PF10443.9 KFM60143.1 - 0.16 10.7 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein AAA_23 PF13476.6 KFM60143.1 - 0.17 12.3 0.1 0.24 11.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFM60143.1 - 0.17 12.2 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4817 PF16087.5 KFM60144.1 - 4e-13 48.9 0.1 6.6e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 KFM60144.1 - 0.024 15.2 0.1 0.048 14.3 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_48 PF17906.1 KFM60144.1 - 0.055 13.6 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 HTH domain in Mos1 transposase DAGK_acc PF00609.19 KFM60145.1 - 2.7e-56 190.3 0.0 3.8e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFM60145.1 - 2.5e-24 85.3 0.0 4.3e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CSD PF00313.22 KFM60146.1 - 1.1e-25 89.3 1.7 1.7e-25 88.6 1.7 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KFM60146.1 - 0.014 15.0 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain eIF-5a PF01287.20 KFM60147.1 - 1e-28 99.2 0.7 1.5e-28 98.7 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KFM60147.1 - 0.034 14.2 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Acyl_transf_3 PF01757.22 KFM60148.1 - 1.6e-05 24.1 6.5 1.6e-05 24.1 6.5 1.7 2 0 0 2 2 2 1 Acyltransferase family LRRC37AB_C PF14914.6 KFM60148.1 - 0.05 13.5 1.3 0.062 13.2 0.4 1.5 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain p450 PF00067.22 KFM60149.1 - 1.3e-72 245.1 2.2 3.5e-72 243.6 2.2 1.7 1 1 0 1 1 1 1 Cytochrome P450 Tox-URI2 PF15653.6 KFM60149.1 - 0.032 14.5 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 URI fold toxin 2 SKG6 PF08693.10 KFM60150.1 - 0.022 14.2 1.4 0.027 13.9 1.4 1.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SCIMP PF15050.6 KFM60150.1 - 0.13 12.7 0.5 0.14 12.6 0.5 1.0 1 0 0 1 1 1 0 SCIMP protein FixQ PF05545.11 KFM60150.1 - 0.15 12.0 0.2 0.16 12.0 0.2 1.1 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ p450 PF00067.22 KFM60151.1 - 2.5e-56 191.3 1.8 1.2e-54 185.8 1.8 2.0 1 1 0 1 1 1 1 Cytochrome P450 ParB_C PF18064.1 KFM60151.1 - 0.013 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal PAS_3 PF08447.12 KFM60151.1 - 0.087 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold p450 PF00067.22 KFM60152.1 - 2.7e-71 240.7 0.0 3.2e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DENN PF02141.21 KFM60153.1 - 2.1e-32 112.6 2.7 6.9e-32 110.9 2.7 1.9 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFM60153.1 - 5.7e-20 71.8 0.4 1.8e-19 70.2 0.4 2.0 1 0 0 1 1 1 1 uDENN domain Alanine_zipper PF11839.8 KFM60153.1 - 0.077 13.4 6.3 0.21 12.0 6.3 1.6 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein RRP36 PF06102.12 KFM60153.1 - 0.73 9.8 7.9 0.3 11.0 4.5 2.1 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 DUF4371 PF14291.6 KFM60154.1 - 7.4e-10 38.9 0.0 2.1e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Wx5_PLAF3D7 PF09688.10 KFM60154.1 - 1.7 8.7 5.5 3.4 7.7 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (Wx5_PLAF3D7) COMM_domain PF07258.14 KFM60155.1 - 4.3e-22 78.0 0.0 7.8e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 COMM domain Ntox14 PF15522.6 KFM60155.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Novel toxin 14 Aldolase_II PF00596.21 KFM60156.1 - 3.6e-44 150.9 0.0 4.2e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CYTH PF01928.21 KFM60157.1 - 2.7e-15 56.7 0.0 3.3e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 CYTH domain B9-C2 PF07162.11 KFM60158.1 - 8.8e-54 182.2 1.5 9.7e-54 182.1 1.5 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF968 PF06147.11 KFM60159.1 - 0.084 13.1 0.8 0.15 12.3 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF968) zf-HIT PF04438.16 KFM60159.1 - 0.55 10.1 4.2 1.2 9.1 4.2 1.5 1 0 0 1 1 1 0 HIT zinc finger BBS1 PF14779.6 KFM60160.1 - 2.6e-60 204.0 0.0 2.9e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 KFM60160.1 - 0.0036 17.3 0.0 0.0048 16.9 0.0 1.4 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region YIF1 PF03878.15 KFM60161.1 - 1.1e-83 280.4 5.4 1.3e-83 280.2 5.4 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KFM60161.1 - 0.00042 20.1 11.7 0.00042 20.1 11.7 1.5 1 1 0 1 1 1 1 Yip1 domain Stevor PF17410.2 KFM60162.1 - 0.0034 17.0 0.5 0.0045 16.6 0.5 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Mid2 PF04478.12 KFM60162.1 - 0.023 14.6 0.4 0.032 14.1 0.4 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KFM60162.1 - 0.03 14.2 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 KFM60162.1 - 0.035 12.9 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Shisa PF13908.6 KFM60162.1 - 0.073 13.3 0.1 0.073 13.3 0.1 2.4 1 1 2 3 3 3 0 Wnt and FGF inhibitory regulator FtsH_ext PF06480.15 KFM60162.1 - 0.095 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsH Extracellular SIT PF15330.6 KFM60162.1 - 0.1 13.0 0.3 9.9 6.6 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Herpes_gE PF02480.16 KFM60162.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FAM176 PF14851.6 KFM60162.1 - 0.79 9.4 2.2 6.1 6.5 1.7 2.1 1 1 1 2 2 2 0 FAM176 family Baculo_11_kDa PF06143.11 KFM60162.1 - 2.8 7.6 4.8 1.5 8.5 2.1 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Ldl_recept_a PF00057.18 KFM60163.1 - 3.4e-09 36.8 11.6 6.4e-09 35.9 11.6 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Cadherin_C_2 PF16492.5 KFM60163.1 - 0.0029 18.3 1.9 0.009 16.7 1.9 1.8 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Orf78 PF06024.12 KFM60163.1 - 0.0037 17.5 0.0 0.007 16.7 0.0 1.5 1 0 0 1 1 1 1 Orf78 (ac78) Collectrin PF16959.5 KFM60163.1 - 0.021 14.6 2.6 0.045 13.5 2.6 1.6 1 0 0 1 1 1 0 Renal amino acid transporter TMEM154 PF15102.6 KFM60163.1 - 0.028 14.3 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF5385 PF17359.2 KFM60163.1 - 0.042 13.4 0.1 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5385) EphA2_TM PF14575.6 KFM60163.1 - 0.044 14.7 0.1 0.12 13.3 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BatD PF13584.6 KFM60163.1 - 0.056 12.2 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Oxygen tolerance ASFV_J13L PF05568.11 KFM60163.1 - 0.073 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4386 PF14329.6 KFM60163.1 - 0.084 12.7 3.0 2.8 7.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) DUF4381 PF14316.6 KFM60163.1 - 0.098 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Neurensin PF14927.6 KFM60163.1 - 0.12 12.1 1.0 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 Neurensin NusG_II PF07009.11 KFM60163.1 - 0.28 11.4 2.1 4.1 7.7 0.1 2.4 2 0 0 2 2 2 0 NusG domain II Ly49 PF08391.10 KFM60163.1 - 0.44 10.9 0.1 0.44 10.9 0.1 2.1 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Syndecan PF01034.20 KFM60163.1 - 0.8 9.7 3.0 1.7 8.6 3.0 1.5 1 0 0 1 1 1 0 Syndecan domain tRNA_anti-like PF12869.7 KFM60163.1 - 1.7 8.2 4.7 0.41 10.3 0.7 2.0 3 0 0 3 3 3 0 tRNA_anti-like DUF2057 PF09829.9 KFM60163.1 - 2.4 8.3 5.3 1.7 8.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Insulin_TMD PF17870.1 KFM60163.1 - 2.9 8.1 6.0 13 6.0 3.3 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment CEP1-DNA_bind PF09287.10 KFM60164.1 - 0.012 15.3 3.6 1.4 8.6 0.3 2.1 1 1 1 2 2 2 0 CEP-1, DNA binding 7tm_1 PF00001.21 KFM60165.1 - 1.2e-70 237.8 16.3 2e-70 237.1 16.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM60165.1 - 5.7e-17 62.0 14.3 1.2e-16 60.9 14.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM60165.1 - 0.0012 18.5 20.5 0.0012 18.5 20.5 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx HTH_Tnp_Tc3_2 PF01498.18 KFM60166.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60166.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60166.1 - 1.7e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60166.1 - 0.0023 17.7 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60166.1 - 1.8 9.3 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM60167.1 - 5.8e-16 58.5 2.2 5.8e-16 58.5 2.2 2.2 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM60167.1 - 1.1e-13 51.2 0.0 2.3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60167.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60167.1 - 0.0027 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60167.1 - 2 9.1 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain F-box-like PF12937.7 KFM60168.1 - 2.5e-05 24.1 2.1 5.1e-05 23.1 2.1 1.6 1 0 0 1 1 1 1 F-box-like Acyltransferase PF01553.21 KFM60168.1 - 0.05 13.2 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Acyltransferase F-box-like PF12937.7 KFM60169.1 - 0.00033 20.5 1.5 0.0007 19.4 1.5 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KFM60170.1 - 0.0032 17.3 2.2 0.0061 16.4 1.0 2.2 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.7 KFM60172.1 - 0.059 13.3 2.5 0.13 12.2 2.5 1.6 1 0 0 1 1 1 0 F-box-like DDE_3 PF13358.6 KFM60174.1 - 0.0034 17.1 0.0 0.0036 17.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCCH_6 PF18585.1 KFM60176.1 - 0.0084 16.0 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Epimerase PF01370.21 KFM60178.1 - 7.3e-23 81.3 0.0 1.1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM60178.1 - 4.4e-22 78.4 0.0 6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFM60178.1 - 2.4e-14 53.6 0.0 3.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFM60178.1 - 1.2e-11 44.3 0.1 1.5e-10 40.6 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KFM60178.1 - 3.3e-11 43.2 0.0 6.8e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFM60178.1 - 1.4e-10 41.1 0.1 5.3e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 KFM60178.1 - 3.5e-06 27.0 0.0 7.6e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFM60178.1 - 4.4e-05 22.8 0.0 6.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFM60178.1 - 5.1e-05 22.5 0.1 8.2e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KFM60178.1 - 0.0018 17.8 0.0 0.016 14.7 0.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM60178.1 - 0.12 12.0 0.0 0.4 10.2 0.0 1.9 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase EBV-NA3 PF05009.12 KFM60178.1 - 0.34 10.4 2.7 0.59 9.6 2.7 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) AMP-binding PF00501.28 KFM60179.1 - 3.4e-97 325.7 0.0 5.7e-59 199.8 0.0 2.6 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KFM60179.1 - 4e-15 56.6 0.9 4e-15 56.6 0.9 1.8 2 0 0 2 2 2 1 DMAP1-binding Domain Spore_YhcN_YlaJ PF09580.10 KFM60179.1 - 5.9 7.0 7.0 0.9 9.6 1.3 2.2 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Med20 PF08612.11 KFM60180.1 - 8.1e-22 77.7 0.0 8.9e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex RIBIOP_C PF04950.12 KFM60181.1 - 1.6e-114 382.2 0.8 3.2e-114 381.3 0.8 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFM60181.1 - 1.1e-21 76.7 0.0 4.5e-21 74.7 0.0 2.1 2 0 0 2 2 2 1 AARP2CN (NUC121) domain IBB PF01749.20 KFM60181.1 - 0.038 14.4 0.2 0.038 14.4 0.2 2.4 2 0 0 2 2 2 0 Importin beta binding domain BESS PF02944.20 KFM60181.1 - 0.24 11.3 1.8 0.87 9.5 0.2 2.8 2 0 0 2 2 2 0 BESS motif Gar1 PF04410.14 KFM60182.1 - 3.1e-44 150.5 0.7 6e-44 149.5 0.7 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF4023 PF13215.6 KFM60182.1 - 2.6 8.1 0.0 2.6 8.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4023) BK_channel_a PF03493.18 KFM60184.1 - 4.5e-38 129.4 0.0 8.6e-38 128.5 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KFM60184.1 - 3e-16 59.2 4.8 3e-16 59.2 4.8 3.2 4 0 0 4 4 4 1 Ion channel Ion_trans PF00520.31 KFM60184.1 - 4.5e-16 58.8 21.3 2.3e-15 56.5 19.2 2.3 2 0 0 2 2 2 1 Ion transport protein TrkA_N PF02254.18 KFM60184.1 - 0.036 14.3 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DDE_3 PF13358.6 KFM60185.1 - 5.6e-16 58.6 0.1 5.9e-15 55.3 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60185.1 - 3e-15 56.2 7.0 5.6e-15 55.4 7.0 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM60185.1 - 0.00066 20.2 1.9 0.00066 20.2 1.9 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM60185.1 - 0.0027 17.4 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60185.1 - 0.015 15.4 0.1 0.065 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM60185.1 - 0.032 14.3 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Dimer_Tnp_hAT PF05699.14 KFM60186.1 - 2.4e-06 27.2 0.0 8.2e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4371 PF14291.6 KFM60186.1 - 4.2e-06 26.6 0.0 4.2e-06 26.6 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM60186.1 - 0.015 14.8 0.1 0.036 13.7 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type TPR_11 PF13414.6 KFM60187.1 - 0.052 13.3 0.1 0.53 10.0 0.1 2.1 1 1 1 2 2 2 0 TPR repeat Myb_DNA-bind_5 PF13873.6 KFM60188.1 - 0.0058 16.7 0.1 0.0097 16.0 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 KFM60189.1 - 5.9e-15 55.3 0.0 7.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM60189.1 - 7.4e-07 29.0 0.0 9.2e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein amfpi-1 PF12190.8 KFM60189.1 - 0.0042 17.7 0.8 0.0087 16.7 0.9 1.5 1 1 1 2 2 2 1 Fungal protease inhibitor DDE_Tnp_1_2 PF13586.6 KFM60189.1 - 0.096 13.1 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain Adap_comp_sub PF00928.21 KFM60190.1 - 3.5e-47 161.0 0.2 3.5e-47 161.0 0.2 2.1 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Plug_translocon PF10559.9 KFM60192.1 - 0.076 12.9 0.0 0.095 12.6 0.0 1.1 1 0 0 1 1 1 0 Plug domain of Sec61p adh_short_C2 PF13561.6 KFM60194.1 - 9.1e-10 38.5 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM60194.1 - 1.2e-09 37.9 0.1 2.2e-09 37.1 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KFM60194.1 - 1.6e-05 24.5 0.0 8.3e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family UCR_TM PF02921.14 KFM60194.1 - 0.14 12.6 0.3 3.1 8.3 0.3 2.6 2 1 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region Methyltr_RsmB-F PF01189.17 KFM60195.1 - 3.2e-25 88.9 0.0 3.2e-25 88.9 0.0 3.2 4 0 0 4 4 4 1 16S rRNA methyltransferase RsmB/F HTH_Tnp_Tc3_2 PF01498.18 KFM60197.1 - 6.8e-08 32.6 0.0 8.1e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Transposase DUF2151 PF10221.9 KFM60198.1 - 2.8e-276 918.6 1.6 3.2e-276 918.4 1.6 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator DUF1542 PF07564.11 KFM60199.1 - 0.011 15.8 2.2 5.1 7.3 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Mcm10 PF09332.11 KFM60200.1 - 1.7e-73 248.1 30.1 1.8e-73 248.0 18.5 2.6 2 1 1 3 3 3 2 Mcm10 replication factor BLACT_WH PF17778.1 KFM60200.1 - 0.11 12.5 0.3 0.9 9.6 0.0 2.6 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain TMEM131_like PF12371.8 KFM60201.1 - 6.3e-19 68.0 0.5 1.3e-18 67.0 0.1 1.7 2 0 0 2 2 2 1 Transmembrane protein 131-like ASH PF15780.5 KFM60201.1 - 0.0026 17.9 0.0 0.0068 16.6 0.0 1.7 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin HTH_Tnp_Tc3_2 PF01498.18 KFM60204.1 - 3.8e-16 59.1 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60204.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60204.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60204.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60204.1 - 1.8 9.3 15.6 0.11 13.1 1.9 3.3 2 1 1 3 3 3 0 Homeodomain-like domain Snf7 PF03357.21 KFM60205.1 - 8.1e-39 133.0 10.3 1.2e-38 132.5 10.3 1.2 1 0 0 1 1 1 1 Snf7 HHH_3 PF12836.7 KFM60205.1 - 0.035 14.4 0.4 6.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Gal_mutarotas_3 PF18080.1 KFM60205.1 - 0.055 13.4 1.7 0.062 13.2 1.7 1.1 1 0 0 1 1 1 0 Galactose mutarotase-like fold domain Adenine_glyco PF03352.13 KFM60205.1 - 0.056 13.2 2.6 0.12 12.2 2.6 1.5 1 0 0 1 1 1 0 Methyladenine glycosylase YqaH PF17448.2 KFM60205.1 - 0.067 13.5 2.5 2.2 8.7 0.2 2.7 2 1 1 3 3 3 0 Uncharacterized YqaH-like zf-ZPR1 PF03367.13 KFM60205.1 - 0.074 12.9 2.8 0.081 12.8 1.6 1.6 1 1 0 1 1 1 0 ZPR1 zinc-finger domain DHC PF09626.10 KFM60205.1 - 0.17 12.8 0.8 11 6.9 0.2 2.3 1 1 0 2 2 2 0 Dihaem cytochrome c PSD4 PF07631.11 KFM60205.1 - 0.94 10.0 7.8 0.088 13.4 1.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1592) Seryl_tRNA_N PF02403.22 KFM60205.1 - 9.7 6.5 16.7 1.8 8.8 3.2 3.0 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Tombus_P19 PF03220.13 KFM60206.1 - 0.064 13.0 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Tombusvirus P19 core protein Peptidase_S9 PF00326.21 KFM60207.1 - 0.014 14.9 0.0 0.014 14.9 0.0 1.0 1 0 0 1 1 1 0 Prolyl oligopeptidase family Synaptobrevin PF00957.21 KFM60208.1 - 0.0029 17.4 0.1 0.0029 17.4 0.1 1.6 2 0 0 2 2 2 1 Synaptobrevin SH PF01445.17 KFM60209.1 - 0.086 12.8 1.7 0.1 12.6 1.7 1.1 1 0 0 1 1 1 0 Viral small hydrophobic protein zf-H2C2_5 PF13909.6 KFM60210.1 - 6.5e-08 32.2 3.6 6.5e-08 32.2 3.6 3.2 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM60210.1 - 2.3e-07 31.1 14.0 0.00014 22.4 1.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM60210.1 - 2.7e-07 30.7 11.2 3.4e-05 24.1 0.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60210.1 - 3.2e-06 27.3 16.6 0.0015 18.9 2.9 2.7 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KFM60210.1 - 1.9e-05 24.3 3.0 1.9e-05 24.3 3.0 2.3 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFM60210.1 - 0.0036 18.0 1.8 0.0082 16.8 1.5 1.6 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KFM60210.1 - 0.0058 16.9 3.9 0.01 16.1 3.9 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KFM60210.1 - 0.023 15.2 1.1 2.6 8.6 0.1 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 KFM60210.1 - 0.024 14.8 1.4 0.9 9.7 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 KFM60210.1 - 0.067 13.5 5.0 0.063 13.6 4.4 1.3 1 1 0 1 1 1 0 C2H2-type zinc ribbon Zn_ribbon_SprT PF17283.2 KFM60210.1 - 0.072 13.0 4.6 0.099 12.6 3.7 1.7 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Fer4_9 PF13187.6 KFM60210.1 - 0.35 11.1 4.9 1.8 8.8 2.5 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Actin_micro PF17003.5 KFM60210.1 - 0.38 9.9 6.6 0.59 9.3 1.1 2.0 1 1 1 2 2 2 0 Putative actin-like family zf-met PF12874.7 KFM60210.1 - 0.59 10.6 11.2 0.93 10.0 0.2 2.7 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-Mss51 PF13824.6 KFM60210.1 - 6.8 6.9 7.0 29 4.9 0.9 2.7 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-H2C2_2 PF13465.6 KFM60211.1 - 5.9e-11 42.3 12.2 3.9e-05 23.9 0.8 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM60211.1 - 2.2e-07 31.1 16.0 0.021 15.6 1.8 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM60211.1 - 2.2e-06 27.3 2.8 3.4e-05 23.5 0.5 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM60211.1 - 2.6e-06 27.5 22.5 0.00098 19.5 2.7 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.7 KFM60211.1 - 0.0027 18.0 13.7 0.046 14.1 0.9 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type YyzF PF14116.6 KFM60211.1 - 0.019 15.0 0.6 0.95 9.5 0.0 2.8 3 0 0 3 3 3 0 YyzF-like protein zf-H2C2_2 PF13465.6 KFM60213.1 - 2.4e-16 59.3 21.7 1.5e-08 34.7 1.6 3.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60213.1 - 9.9e-14 50.9 22.3 0.0003 21.1 3.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60213.1 - 1.1e-10 41.4 17.9 0.0046 17.7 2.2 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM60213.1 - 5.7e-08 32.4 0.4 5.7e-08 32.4 0.4 3.6 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFM60213.1 - 0.0006 20.1 6.7 0.036 14.5 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60213.1 - 0.00073 19.8 3.3 0.44 10.9 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 KFM60213.1 - 0.0079 16.6 2.3 2.9 8.4 0.1 3.5 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_7 PF15269.6 KFM60213.1 - 0.011 15.8 0.2 0.011 15.8 0.2 2.5 1 1 2 3 3 3 0 Zinc-finger zf-Di19 PF05605.12 KFM60213.1 - 0.098 13.0 7.3 0.085 13.2 2.2 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFM60213.1 - 0.17 12.3 4.5 7.5 7.0 0.1 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM60213.1 - 0.36 10.5 6.3 1.2 8.8 0.2 2.9 3 0 0 3 3 3 0 MYST family zinc finger domain FYVE PF01363.21 KFM60213.1 - 3.3 7.9 9.9 9.5 6.4 8.0 2.3 1 1 1 2 2 2 0 FYVE zinc finger zf-met PF12874.7 KFM60216.1 - 0.00042 20.6 0.9 0.00042 20.6 0.9 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60216.1 - 0.00069 19.8 0.6 0.00069 19.8 0.6 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFM60216.1 - 0.00081 20.0 0.6 0.00081 20.0 0.6 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM60216.1 - 0.0033 17.8 0.9 0.0033 17.8 0.9 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM60216.1 - 0.028 14.4 4.6 0.066 13.2 4.6 1.7 1 1 0 1 1 1 0 C2H2-type zinc finger LIM PF00412.22 KFM60216.1 - 0.053 13.7 0.3 0.079 13.2 0.3 1.4 1 1 0 1 1 1 0 LIM domain zf-DNA_Pol PF08996.10 KFM60216.1 - 0.057 13.2 0.1 0.057 13.2 0.1 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF629 PF04780.12 KFM60216.1 - 0.095 11.2 1.2 0.11 11.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.6 KFM60216.1 - 0.12 12.9 0.4 0.12 12.9 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Oxidored_FMN PF00724.20 KFM60216.1 - 0.12 11.6 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family PfkB PF00294.24 KFM60217.1 - 5.4e-35 121.2 0.0 6.4e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HTH_28 PF13518.6 KFM60218.1 - 0.00051 20.1 0.0 0.00081 19.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM60218.1 - 0.00071 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KFM60218.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain MSG PF02349.15 KFM60219.1 - 0.015 15.5 11.3 0.015 15.5 11.3 4.2 4 2 1 5 5 5 0 Major surface glycoprotein 7tm_1 PF00001.21 KFM60220.1 - 1.6e-11 44.1 7.4 2.4e-11 43.5 7.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM60220.1 - 0.003 17.0 5.2 0.0035 16.8 5.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CRAL_TRIO_2 PF13716.6 KFM60222.1 - 1.3e-26 93.4 0.1 3.5e-26 92.0 0.1 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_mid PF14228.6 KFM60222.1 - 8.6e-07 27.0 4.0 2.3e-05 22.3 0.1 2.2 1 1 1 2 2 2 2 Cell morphogenesis central region CRAL_TRIO PF00650.20 KFM60222.1 - 0.00086 19.1 0.2 0.0021 17.8 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain Ribosomal_L18A PF01775.17 KFM60222.1 - 0.03 14.4 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CBM_14 PF01607.24 KFM60223.1 - 2e-11 43.9 3.4 3e-11 43.3 3.4 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain SSP160 PF06933.11 KFM60223.1 - 0.91 7.6 10.6 1.4 7.0 10.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 KFM60223.1 - 7.1 7.1 9.5 19 5.7 9.5 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDE_3 PF13358.6 KFM60224.1 - 3e-08 33.5 0.0 3.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC_4 PF14392.6 KFM60227.1 - 0.99 9.2 15.0 0.3 10.9 0.9 2.8 3 0 0 3 3 3 0 Zinc knuckle SWIM PF04434.17 KFM60228.1 - 0.00044 19.8 2.5 0.0008 19.0 2.5 1.4 1 0 0 1 1 1 1 SWIM zinc finger Cnd1 PF12717.7 KFM60228.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 RPOL_N PF14700.6 KFM60229.1 - 5.6e-25 88.5 0.0 8.2e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 KFM60230.1 - 4.1e-08 33.3 1.7 2.8e-05 24.2 0.0 4.0 4 0 0 4 4 4 1 PPR repeat family PPR_3 PF13812.6 KFM60230.1 - 7.3e-07 29.2 1.2 3.1e-05 24.0 0.0 3.5 4 1 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.20 KFM60230.1 - 2e-06 27.7 0.0 0.00029 20.9 0.0 3.6 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 KFM60230.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KFM60230.1 - 0.0049 17.3 0.4 0.011 16.1 0.4 1.6 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_1 PF12854.7 KFM60230.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 PPR repeat Fungal_KA1 PF16797.5 KFM60233.1 - 0.033 13.9 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 Fungal kinase associated-1 domain DDE_3 PF13358.6 KFM60234.1 - 1.1e-06 28.5 0.0 1.8e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM60234.1 - 1.1e-05 26.0 5.3 0.00012 22.6 1.6 2.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM60234.1 - 0.0014 18.4 0.8 0.093 12.6 0.2 2.8 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KFM60234.1 - 0.0016 17.9 0.2 0.0039 16.7 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 KFM60234.1 - 0.0021 17.4 0.1 0.055 12.9 0.1 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.7 KFM60234.1 - 0.0029 17.7 0.1 0.15 12.3 0.0 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_10 PF04967.12 KFM60234.1 - 0.0045 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 HTH DNA binding domain HTH_19 PF12844.7 KFM60234.1 - 0.008 16.2 0.3 0.02 14.9 0.1 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 KFM60234.1 - 0.013 15.0 0.1 0.037 13.6 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Mga PF08280.11 KFM60234.1 - 0.037 14.1 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_Tc3_2 PF01498.18 KFM60234.1 - 0.039 14.2 1.1 0.039 14.2 1.1 2.4 3 0 0 3 3 2 0 Transposase PCI PF01399.27 KFM60234.1 - 0.042 14.4 0.0 0.073 13.6 0.0 1.4 1 0 0 1 1 1 0 PCI domain DUF3071 PF11268.8 KFM60234.1 - 0.044 13.8 0.4 0.079 13.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) ANT PF03374.14 KFM60234.1 - 0.053 13.8 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain Sigma70_r3 PF04539.16 KFM60234.1 - 0.077 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 HTH_28 PF13518.6 KFM60234.1 - 0.12 12.6 1.2 2.1 8.6 0.2 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Acetyltransf_1 PF00583.25 KFM60235.1 - 2.7e-09 37.3 0.1 3.8e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM60235.1 - 7.7e-08 32.3 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM60235.1 - 3.9e-06 27.2 0.0 6.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFM60235.1 - 4.3e-06 27.0 0.0 8.1e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFM60235.1 - 2.5e-05 24.9 0.0 3.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM60235.1 - 0.015 15.2 0.0 0.05 13.6 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein MKT1_N PF12247.8 KFM60236.1 - 0.11 12.9 0.6 1.7 9.1 0.0 2.1 1 1 1 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication DUF5641 PF18701.1 KFM60236.1 - 0.67 10.2 4.7 1.1 9.5 4.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5641) CUB PF00431.20 KFM60237.1 - 3.5e-15 56.3 0.0 1e-07 32.3 0.0 4.6 5 0 0 5 5 5 3 CUB domain CUB_2 PF02408.20 KFM60237.1 - 0.041 13.6 0.2 2 8.2 0.1 2.7 2 0 0 2 2 2 0 CUB-like domain GATA PF00320.27 KFM60239.1 - 2.3e-28 97.5 24.7 1.2e-14 53.6 7.4 2.7 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFM60239.1 - 2.3e-05 23.8 8.6 0.029 13.9 0.7 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.10 KFM60239.1 - 0.013 15.6 4.0 2.8 8.2 0.3 3.2 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.10 KFM60239.1 - 0.019 15.1 2.5 2.3 8.4 0.1 2.9 2 1 0 2 2 2 0 Zinc ribbon domain ArfGap PF01412.18 KFM60239.1 - 0.023 14.8 6.4 0.19 11.8 0.4 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Elf1 PF05129.13 KFM60239.1 - 0.039 14.0 2.6 3.2 7.9 0.5 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Auto_anti-p27 PF06677.12 KFM60239.1 - 0.061 13.5 5.9 1.7 8.9 0.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SelP_N PF04592.14 KFM60239.1 - 0.12 11.7 9.6 0.24 10.8 9.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Prim_Zn_Ribbon PF08273.12 KFM60239.1 - 0.34 11.2 9.0 0.47 10.8 2.1 2.8 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase OrfB_Zn_ribbon PF07282.11 KFM60239.1 - 0.34 10.9 8.4 3.1 7.8 1.1 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RRPl_C4 PF17026.5 KFM60239.1 - 0.68 10.1 3.4 24 5.1 2.4 2.2 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type eIF-5_eIF-2B PF01873.17 KFM60239.1 - 1 9.3 6.6 5.8 6.8 1.7 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.7 KFM60239.1 - 1 9.5 8.8 12 6.0 0.7 2.9 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFM60239.1 - 5.3 7.9 6.5 11 6.8 1.4 3.2 2 1 2 4 4 3 0 zinc-ribbon family NicO PF03824.16 KFM60239.1 - 5.9 6.1 6.2 9.2 5.5 6.2 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein HEAT_EZ PF13513.6 KFM60240.1 - 6e-20 71.3 7.8 2.4e-10 40.7 0.0 8.8 10 0 0 10 10 9 2 HEAT-like repeat HEAT PF02985.22 KFM60240.1 - 1.3e-19 68.6 10.0 6.1e-05 22.9 0.0 8.8 9 1 0 9 9 9 3 HEAT repeat IBN_N PF03810.19 KFM60240.1 - 4.7e-14 52.1 1.5 3.1e-12 46.2 0.2 3.5 2 1 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KFM60240.1 - 5.2e-09 36.4 3.3 0.00086 19.7 0.0 6.6 4 2 3 7 7 7 1 HEAT repeats MMS19_C PF12460.8 KFM60240.1 - 2.7e-06 26.8 1.3 0.098 11.8 0.9 3.7 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 KFM60240.1 - 4.4e-05 23.6 3.2 0.01 15.9 0.0 4.2 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFM60240.1 - 9e-05 21.2 5.4 0.0018 16.9 0.2 2.8 2 1 1 3 3 3 3 Adaptin N terminal region Arm PF00514.23 KFM60240.1 - 0.0002 21.2 7.5 0.042 13.9 0.0 5.5 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat TIMELESS PF04821.14 KFM60240.1 - 0.0042 16.4 0.1 0.022 14.0 0.0 2.2 3 0 0 3 3 3 1 Timeless protein IFRD PF05004.13 KFM60240.1 - 0.0059 15.7 7.0 0.91 8.6 0.3 4.7 3 1 1 5 5 5 2 Interferon-related developmental regulator (IFRD) DUF4042 PF13251.6 KFM60240.1 - 0.013 15.2 0.0 13 5.4 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) V-ATPase_H_C PF11698.8 KFM60240.1 - 0.019 15.1 1.8 0.13 12.4 0.1 2.9 2 0 0 2 2 2 0 V-ATPase subunit H Cnd3 PF12719.7 KFM60240.1 - 0.04 13.1 3.8 0.048 12.9 0.1 2.8 3 2 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain UME PF08064.13 KFM60240.1 - 0.12 12.3 4.9 21 5.1 0.2 4.9 4 1 0 4 4 4 0 UME (NUC010) domain DDE_1 PF03184.19 KFM60241.1 - 4.9e-50 169.6 0.1 8.6e-50 168.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM60241.1 - 2.4e-12 46.7 0.0 1.8e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain RICH PF05062.12 KFM60242.1 - 0.019 15.3 1.4 0.039 14.3 1.4 1.4 1 0 0 1 1 1 0 RICH domain zf-C2H2 PF00096.26 KFM60242.1 - 0.12 12.9 1.6 15 6.3 0.2 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 KFM60242.1 - 5.2 7.6 8.7 5.3 7.6 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PriX PF18689.1 KFM60243.1 - 0.082 13.3 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Primase X RVT_1 PF00078.27 KFM60245.1 - 0.00067 19.2 0.1 0.00088 18.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM60246.1 - 1.4e-19 70.4 0.0 2.8e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 KFM60246.1 - 1e-15 57.6 0.8 1e-15 57.6 0.8 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KFM60246.1 - 2.1e-08 33.9 2.7 2.8e-08 33.5 0.4 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.23 KFM60246.1 - 1.5e-05 24.8 7.3 0.00011 22.1 1.3 3.4 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.6 KFM60246.1 - 0.031 14.0 1.5 0.059 13.1 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle WD40 PF00400.32 KFM60247.1 - 0.0066 17.3 0.0 31 5.7 0.0 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat TPR_19 PF14559.6 KFM60248.1 - 5.1e-06 26.9 0.3 1.1e-05 25.8 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM60248.1 - 5.7e-06 25.9 5.6 0.0051 16.6 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM60248.1 - 3.8e-05 23.5 4.4 0.22 11.8 0.1 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM60248.1 - 0.00036 20.7 1.1 0.00036 20.7 1.1 1.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KFM60248.1 - 0.00046 20.8 1.1 0.0029 18.3 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM60248.1 - 0.001 19.1 1.1 0.36 11.2 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM60248.1 - 0.0036 17.9 0.1 0.01 16.5 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM60248.1 - 0.0049 16.5 1.1 0.0068 16.1 0.3 1.6 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 KFM60248.1 - 0.01 16.2 0.3 0.087 13.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM60248.1 - 0.065 13.9 0.5 0.5 11.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_Tnp_Tc3_2 PF01498.18 KFM60251.1 - 1.5e-07 31.5 0.7 1.5e-07 31.5 0.7 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60251.1 - 1.7e-07 31.1 0.2 1.1e-06 28.4 0.1 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease Sarcoglycan_1 PF04790.13 KFM60252.1 - 9.1e-80 267.7 0.0 1e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFM60252.1 - 0.0063 16.4 0.9 0.66 9.8 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) Coat_X PF07552.11 KFM60252.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Spore Coat Protein X and V domain DDE_3 PF13358.6 KFM60253.1 - 7.1e-16 58.3 0.8 5.7e-15 55.4 0.0 2.5 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60253.1 - 7.5e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM60253.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60253.1 - 0.0066 17.0 1.4 0.0066 17.0 1.4 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM60253.1 - 0.014 15.4 0.5 0.014 15.4 0.5 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 KFM60253.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.6 KFM60254.1 - 3.7e-16 59.2 0.1 5.5e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60254.1 - 8.1e-16 58.0 6.5 1.4e-15 57.3 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM60254.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM60254.1 - 0.0028 17.4 0.1 0.12 12.2 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM60254.1 - 0.016 15.2 0.4 0.016 15.2 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM60254.1 - 0.061 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KFM60256.1 - 4.9e-16 58.7 3.5 6.1e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60256.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60256.1 - 3e-07 30.1 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60256.1 - 0.0029 17.4 0.6 0.008 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60256.1 - 2.8 8.6 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ATP-synt_C PF00137.21 KFM60257.1 - 5.3e-37 126.0 38.4 1.7e-22 79.5 13.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C NHL PF01436.21 KFM60258.1 - 1.8e-45 150.7 25.5 6.1e-08 32.3 0.2 6.8 6 0 0 6 6 6 6 NHL repeat Filamin PF00630.19 KFM60258.1 - 1.3e-16 61.3 0.1 5.6e-16 59.2 0.0 2.2 2 0 0 2 2 1 1 Filamin/ABP280 repeat DUF5128 PF17170.4 KFM60258.1 - 1.6e-16 60.4 1.0 7.5e-06 25.3 0.1 3.9 2 2 2 4 4 4 3 6-bladed beta-propeller SGL PF08450.12 KFM60258.1 - 3.9e-12 46.3 2.8 0.0021 17.7 0.0 4.9 1 1 4 5 5 5 3 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 KFM60258.1 - 1.5e-08 34.6 4.5 1.5e-08 34.6 4.5 3.7 3 2 0 3 3 2 2 B-box zinc finger zf-RING_UBOX PF13445.6 KFM60258.1 - 1.3e-07 31.5 5.4 1.3e-07 31.5 5.4 3.0 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM60258.1 - 3.8e-07 29.9 7.5 3.8e-07 29.9 7.5 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM60258.1 - 7e-07 29.0 9.1 7e-07 29.0 9.1 3.7 4 1 1 5 5 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM60258.1 - 6.2e-06 26.4 7.7 6.2e-06 26.4 7.7 4.0 4 0 0 4 4 3 1 Ring finger domain zf-RING_5 PF14634.6 KFM60258.1 - 7.4e-06 25.8 6.4 7.4e-06 25.8 6.4 3.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM60258.1 - 1.2e-05 25.1 6.2 1.2e-05 25.1 6.2 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Neurexophilin PF06312.12 KFM60258.1 - 0.00082 18.9 0.0 0.0024 17.4 0.0 1.8 1 0 0 1 1 1 1 Neurexophilin zf-C3HC4_4 PF15227.6 KFM60258.1 - 0.0016 18.6 10.5 0.0016 18.6 10.5 3.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFM60258.1 - 0.0042 16.9 7.2 0.0042 16.9 7.2 3.4 3 0 0 3 3 1 1 Prokaryotic RING finger family 4 Invasin_D3 PF09134.10 KFM60258.1 - 0.0042 17.3 0.0 0.078 13.3 0.0 2.4 2 0 0 2 2 2 1 Invasin, domain 3 DUF4455 PF14643.6 KFM60258.1 - 0.0068 15.1 5.0 0.0099 14.6 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) zf-ANAPC11 PF12861.7 KFM60258.1 - 0.027 14.5 1.1 0.027 14.5 1.1 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger YtkA PF13115.6 KFM60258.1 - 0.036 14.7 0.0 0.088 13.4 0.0 1.7 1 0 0 1 1 1 0 YtkA-like KCNQ_channel PF03520.14 KFM60258.1 - 0.14 12.0 3.3 0.27 11.1 3.3 1.5 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel NACHT PF05729.12 KFM60258.1 - 0.16 11.9 0.2 0.43 10.5 0.2 1.7 2 0 0 2 2 1 0 NACHT domain FlgN PF05130.12 KFM60258.1 - 0.24 11.9 5.3 3.9 8.0 4.2 2.3 1 1 1 2 2 2 0 FlgN protein Tmemb_185A PF10269.9 KFM60260.1 - 1.6e-22 80.4 25.2 1.7e-22 80.3 25.2 1.0 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein EF-hand_1 PF00036.32 KFM60262.1 - 0.006 16.0 0.1 0.006 16.0 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFM60262.1 - 0.017 15.0 2.2 0.018 14.9 0.1 2.1 2 1 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 KFM60262.1 - 0.052 13.4 0.0 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KFM60263.1 - 1.7e-09 36.6 0.2 3.5e-08 32.4 0.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFM60263.1 - 5.6e-09 35.7 0.0 9.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KFM60263.1 - 1.2e-08 35.3 0.0 1.9e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFM60263.1 - 2.1e-08 33.5 0.1 1.1e-07 31.2 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KFM60263.1 - 4.6e-07 29.0 0.4 4.7e-06 25.9 0.2 2.1 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 KFM60263.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Asparaginase PF00710.20 KFM60263.1 - 0.02 14.5 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Asparaginase, N-terminal TerB PF05099.13 KFM60263.1 - 0.064 13.2 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB Ribosomal_S14 PF00253.21 KFM60264.1 - 1.4e-16 60.0 0.2 2.6e-16 59.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3585 PF12130.8 KFM60267.1 - 3.1e-37 127.7 29.9 3.1e-37 127.7 29.9 2.1 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain LIM PF00412.22 KFM60267.1 - 6e-08 32.8 3.5 1.2e-07 31.8 3.5 1.5 1 0 0 1 1 1 1 LIM domain zf-Sec23_Sec24 PF04810.15 KFM60267.1 - 0.069 13.2 1.1 0.31 11.1 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF2868 PF11067.8 KFM60267.1 - 1.1 8.7 2.9 2.8 7.4 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) GAS2 PF02187.17 KFM60268.1 - 2.8e-12 46.5 0.4 5.8e-12 45.5 0.4 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Gp5_C PF06715.12 KFM60269.1 - 0.072 13.3 3.6 0.12 12.6 3.6 1.4 1 0 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) FANCI_S4 PF14678.6 KFM60270.1 - 3.3e-70 236.1 4.8 3.3e-70 236.1 4.8 1.6 2 0 0 2 2 2 1 FANCI solenoid 4 FANCI_S3 PF14677.6 KFM60270.1 - 9.5e-12 45.1 4.0 9.5e-12 45.1 4.0 3.3 2 1 1 3 3 3 1 FANCI solenoid 3 UPF0147 PF03685.13 KFM60270.1 - 0.015 15.3 0.3 12 6.0 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) FANCI_HD2 PF14680.6 KFM60271.1 - 1.4e-38 132.6 4.0 1.7e-38 132.2 4.0 1.1 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_S2 PF14676.6 KFM60271.1 - 0.00019 21.8 1.3 0.00033 21.0 0.1 2.0 2 0 0 2 2 2 1 FANCI solenoid 2 Chorein_N PF12624.7 KFM60271.1 - 0.13 12.4 1.3 3.4 7.8 0.2 2.6 1 1 1 2 2 2 0 N-terminal region of Chorein or VPS13 FANCI_S1 PF14675.6 KFM60272.1 - 1.2e-48 165.6 5.4 1.9e-48 165.0 5.4 1.3 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_HD1 PF14679.6 KFM60272.1 - 7.6e-17 61.1 1.0 7.6e-17 61.1 1.0 2.3 3 0 0 3 3 3 1 FANCI helical domain 1 FANCI_S2 PF14676.6 KFM60272.1 - 1.7e-16 61.0 0.0 7.4e-16 58.9 0.0 2.2 1 0 0 1 1 1 1 FANCI solenoid 2 ETF_QO PF05187.13 KFM60273.1 - 1.3e-45 153.7 0.0 2.4e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 KFM60273.1 - 2e-09 37.0 0.6 5.4e-06 25.8 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFM60273.1 - 3e-09 36.9 0.4 0.00015 21.5 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM60273.1 - 3.4e-08 33.6 0.2 1.8e-07 31.3 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFM60273.1 - 6.5e-08 32.2 0.0 9.2e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM60273.1 - 2e-07 30.5 0.1 9e-06 25.1 0.3 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KFM60273.1 - 3.9e-06 26.5 0.1 6.2e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFM60273.1 - 1.1e-05 24.5 0.6 0.00055 18.9 0.3 2.6 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 KFM60273.1 - 2.4e-05 23.2 0.4 3.8e-05 22.6 0.4 1.3 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 KFM60273.1 - 0.00011 22.2 0.1 0.00023 21.2 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFM60273.1 - 0.00019 21.9 0.5 0.16 12.6 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM60273.1 - 0.00039 19.8 0.6 0.00096 18.5 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KFM60273.1 - 0.0013 17.8 0.3 0.0018 17.4 0.3 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.7 KFM60273.1 - 0.0028 18.2 1.4 0.01 16.4 1.1 2.1 2 0 0 2 2 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 KFM60273.1 - 0.012 14.8 0.5 0.021 14.1 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFM60273.1 - 0.017 14.4 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFM60273.1 - 0.051 12.7 0.5 0.074 12.1 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 KFM60273.1 - 0.14 12.3 0.7 0.56 10.4 0.7 2.0 1 0 0 1 1 1 0 4Fe-4S binding domain Ricin_B_lectin PF00652.22 KFM60274.1 - 2.7e-26 92.3 1.6 3.8e-26 91.8 1.6 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFM60274.1 - 1.4e-06 27.8 0.9 2.7e-06 26.9 0.9 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 KFM60274.1 - 0.0028 18.3 0.0 0.067 13.9 0.0 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KFM60274.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Glyco_tranf_2_2 PF10111.9 KFM60274.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFM60276.1 - 1.4e-07 31.5 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Zw10 PF06248.13 KFM60277.1 - 3.5e-87 293.2 24.9 6.1e-87 292.4 24.9 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 PUF PF00806.19 KFM60277.1 - 0.0095 15.6 0.0 0.038 13.7 0.0 2.1 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat Baculo_PEP_C PF04513.12 KFM60277.1 - 0.16 12.0 4.7 0.42 10.6 1.3 3.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3496 PF12001.8 KFM60277.1 - 0.68 10.3 4.3 0.45 10.9 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) ABC_tran_CTD PF16326.5 KFM60277.1 - 7.3 6.9 7.7 0.68 10.2 0.8 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain tRNA-synt_1b PF00579.25 KFM60278.1 - 2.6e-22 79.5 0.0 4.3e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DDE_3 PF13358.6 KFM60279.1 - 0.0001 22.0 0.1 0.00016 21.4 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM60281.1 - 3.8e-16 59.2 0.2 3.3e-15 56.1 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60281.1 - 1.6e-10 41.1 1.0 2.9e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Spectrin PF00435.21 KFM60284.1 - 2e-211 687.1 290.6 1.2e-18 67.5 5.1 35.0 32 4 2 34 34 34 30 Spectrin repeat SH3_10 PF17902.1 KFM60284.1 - 4.3e-24 84.4 0.3 1.2e-23 82.9 0.3 1.9 1 0 0 1 1 1 1 SH3 domain Med9 PF07544.13 KFM60284.1 - 0.00049 20.1 0.8 0.00049 20.1 0.8 19.4 23 3 2 25 25 25 1 RNA polymerase II transcription mediator complex subunit 9 EzrA PF06160.12 KFM60284.1 - 0.00078 17.7 4.6 0.00078 17.7 4.6 17.9 6 3 6 16 16 16 3 Septation ring formation regulator, EzrA RPW8 PF05659.11 KFM60284.1 - 0.049 13.3 0.1 0.049 13.3 0.1 13.6 16 1 0 16 16 16 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF630 PF04783.12 KFM60284.1 - 0.064 13.4 1.4 10 6.4 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF630) Fe-S_assembly PF04384.13 KFM60284.1 - 0.21 12.2 0.0 0.21 12.2 0.0 6.3 5 0 0 5 5 5 0 Iron-sulphur cluster assembly DASH_Dad1 PF08649.10 KFM60284.1 - 0.68 10.2 13.8 22 5.3 0.7 9.0 8 0 0 8 8 8 0 DASH complex subunit Dad1 DUF4248 PF14053.6 KFM60284.1 - 1.1 9.3 3.2 17 5.5 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4248) DUF3138 PF11336.8 KFM60284.1 - 1.2 7.6 4.2 0.33 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) CH PF00307.31 KFM60285.1 - 3.6e-11 43.2 0.1 4e-11 43.1 0.1 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain LysM PF01476.20 KFM60286.1 - 4.2e-07 29.9 0.2 2.3e-06 27.6 0.1 2.2 2 0 0 2 2 2 1 LysM domain DUF2771 PF10969.8 KFM60286.1 - 0.014 15.4 0.1 5 7.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) Poty_coat PF00767.18 KFM60286.1 - 0.026 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Potyvirus coat protein 7tm_1 PF00001.21 KFM60286.1 - 0.062 12.6 0.1 0.096 12.0 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Neur_chan_memb PF02932.16 KFM60286.1 - 1.4 8.9 3.7 2.3 8.2 0.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AMP-binding PF00501.28 KFM60287.1 - 1.3e-88 297.5 0.0 1.6e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM60287.1 - 1.2e-20 74.3 0.1 2.3e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFM60287.1 - 5.3e-16 58.3 1.5 1.9e-15 56.5 1.5 2.1 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus fn3 PF00041.21 KFM60290.1 - 8.9e-07 29.2 0.5 1.8e-05 25.0 0.5 2.1 1 1 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM60290.1 - 0.038 14.5 0.0 0.075 13.6 0.0 1.5 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain SH3_2 PF07653.17 KFM60291.1 - 1.5e-29 101.4 0.0 7.4e-15 54.4 0.0 2.5 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.6 KFM60291.1 - 1.2e-22 79.5 0.9 1.7e-12 47.0 0.1 3.0 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFM60291.1 - 1.3e-15 56.7 1.9 1.8e-07 30.6 0.1 3.3 2 2 0 2 2 2 2 SH3 domain Complex1_LYR PF05347.15 KFM60292.1 - 7e-14 51.6 0.1 8.2e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFM60292.1 - 1.6e-05 25.5 0.5 1.8e-05 25.4 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like ALS2CR8 PF15299.6 KFM60292.1 - 0.013 15.4 0.2 0.014 15.3 0.2 1.0 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 TCTP PF00838.17 KFM60292.1 - 0.056 13.8 0.1 0.058 13.7 0.1 1.1 1 0 0 1 1 1 0 Translationally controlled tumour protein DUF3177 PF11375.8 KFM60295.1 - 0.025 14.4 0.4 0.025 14.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) ABC_tran PF00005.27 KFM60296.1 - 3.6e-43 147.3 0.2 1.2e-29 103.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFM60296.1 - 2.4e-36 125.8 17.5 3.9e-36 125.1 17.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KFM60296.1 - 1.4e-06 27.9 2.0 0.012 15.1 1.2 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFM60296.1 - 0.015 15.4 0.2 0.086 12.9 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 KFM60296.1 - 0.048 13.5 0.0 12 5.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KFM60296.1 - 0.057 13.5 1.9 0.061 13.4 0.3 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain DEAD PF00270.29 KFM60296.1 - 0.082 12.7 1.5 1.3 8.8 1.5 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KFM60296.1 - 0.17 11.5 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF3493 PF11998.8 KFM60296.1 - 0.28 11.4 1.4 0.48 10.6 0.3 1.9 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Glyco_transf_92 PF01697.27 KFM60299.1 - 8.9e-22 78.0 0.2 1.2e-21 77.6 0.2 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFM60299.1 - 0.0032 18.0 0.1 0.0078 16.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 HTH_Tnp_Tc3_2 PF01498.18 KFM60300.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60300.1 - 1.7e-11 44.1 0.0 2.9e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60300.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60300.1 - 0.0025 17.5 0.6 0.0076 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60300.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RVT_1 PF00078.27 KFM60301.1 - 3.4e-27 95.4 0.0 1.2e-26 93.6 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fer4_23 PF18009.1 KFM60301.1 - 0.09 13.2 1.5 4.9 7.7 0.1 2.8 2 1 1 3 3 3 0 4Fe-4S iron-sulfur cluster binding domain MFS_1 PF07690.16 KFM60302.1 - 4.8e-44 150.7 29.2 1.1e-36 126.5 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFM60302.1 - 1.9e-05 23.4 32.1 0.026 13.1 2.2 3.4 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 KFM60302.1 - 0.00012 21.1 31.0 0.0044 15.9 4.2 3.4 2 2 1 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KFM60302.1 - 0.018 13.4 12.8 0.14 10.4 0.1 3.6 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Vps16_C PF04840.12 KFM60303.1 - 3.9e-09 36.0 6.2 1.1e-05 24.6 0.7 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region NAT PF04768.13 KFM60303.1 - 0.03 14.0 0.1 0.069 12.8 0.1 1.6 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase HTH_Tnp_Tc3_2 PF01498.18 KFM60304.1 - 4.6e-16 58.8 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60304.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60304.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60304.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60304.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM60305.1 - 2.2e-16 59.8 2.2 7e-16 58.2 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60305.1 - 1.7e-13 50.5 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60305.1 - 3.8e-07 29.8 1.6 8.4e-07 28.7 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60305.1 - 0.0033 17.2 0.5 0.0091 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60305.1 - 0.038 14.1 0.4 0.11 12.7 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.6 KFM60306.1 - 1.1e-10 41.4 0.0 1.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_1 PF00001.21 KFM60307.1 - 1.5e-58 198.3 0.8 1.5e-58 198.2 0.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM60307.1 - 2.7e-06 27.2 6.5 3.3e-06 26.9 6.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFM60307.1 - 1.1e-05 25.0 2.5 1.5e-05 24.5 2.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFM60307.1 - 0.0012 18.6 1.4 0.0024 17.7 0.5 1.8 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFM60307.1 - 0.014 14.8 0.8 0.024 14.0 0.8 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv GPDPase_memb PF10110.9 KFM60307.1 - 0.026 13.3 0.1 0.038 12.8 0.1 1.2 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase 7tm_1 PF00001.21 KFM60308.1 - 0.049 13.0 0.1 0.069 12.5 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DDE_3 PF13358.6 KFM60309.1 - 2.4e-06 27.4 0.0 5.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 KFM60311.1 - 1.2e-10 41.3 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM60311.1 - 0.0052 17.6 12.3 0.0052 17.6 12.3 2.3 2 0 0 2 2 2 1 DDE_Tnp_1-like zinc-ribbon zf-C5HC2 PF02928.16 KFM60311.1 - 0.034 14.5 8.9 0.046 14.1 7.5 2.1 1 1 0 1 1 1 0 C5HC2 zinc finger DDE_3 PF13358.6 KFM60312.1 - 0.0021 17.8 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60313.1 - 5.2e-16 58.6 1.8 9.5e-16 57.8 1.8 1.4 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM60313.1 - 0.00015 21.9 0.1 0.00015 21.9 0.1 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain PAX PF00292.18 KFM60313.1 - 0.0073 16.2 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 'Paired box' domain MarR_2 PF12802.7 KFM60313.1 - 0.0089 15.9 0.3 1.3 9.0 0.0 2.7 1 1 0 2 2 2 1 MarR family HTH_23 PF13384.6 KFM60313.1 - 0.02 14.7 0.8 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.6 KFM60313.1 - 0.026 14.3 1.3 0.21 11.4 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM60313.1 - 0.033 13.6 2.3 0.16 11.4 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 KFM60313.1 - 1.7 9.3 9.5 0.067 13.8 1.6 2.3 1 1 1 2 2 2 0 Homeodomain-like domain ANAPC4_WD40 PF12894.7 KFM60314.1 - 0.00018 21.7 0.7 0.3 11.4 0.0 3.6 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM60314.1 - 0.0016 19.3 13.4 0.24 12.3 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat RabGAP-TBC PF00566.18 KFM60315.1 - 1.2e-10 41.4 7.8 1.2e-10 41.4 7.8 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF5641 PF18701.1 KFM60317.1 - 9.4e-19 67.4 0.2 9.4e-19 67.4 0.2 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 KFM60317.1 - 8.6e-07 29.0 3.5 8.6e-07 29.0 3.5 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Mago_nashi PF02792.14 KFM60317.1 - 0.16 12.1 0.0 2.7 8.1 0.1 2.2 2 0 0 2 2 2 0 Mago nashi protein DDE_3 PF13358.6 KFM60318.1 - 4.8e-16 58.8 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60318.1 - 7.1e-16 58.2 6.5 1.4e-15 57.2 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM60318.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM60318.1 - 0.0025 17.6 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60318.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM60318.1 - 0.03 14.3 2.6 0.035 14.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HNOB PF07700.15 KFM60319.1 - 2.2e-25 89.5 0.0 3.5e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 KFM60319.1 - 5.3e-21 75.1 0.0 7.6e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Heme NO binding associated KTI12 PF08433.10 KFM60321.1 - 1.7e-05 24.4 0.0 1.7e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF3683 PF12447.8 KFM60325.1 - 0.054 13.6 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) zf-4CXXC_R1 PF10497.9 KFM60326.1 - 0.003 17.8 0.0 0.0037 17.5 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 ABC2_membrane_3 PF12698.7 KFM60326.1 - 0.015 14.5 5.2 0.016 14.3 5.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 KFM60327.1 - 1.3e-07 32.2 0.2 2.1e-07 31.5 0.1 1.4 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KFM60327.1 - 0.00027 21.5 1.4 0.00028 21.5 0.2 1.6 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 KFM60327.1 - 0.0065 16.2 0.1 0.0096 15.6 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM60327.1 - 0.0085 16.0 0.1 0.011 15.6 0.1 1.3 1 1 0 1 1 1 1 RsgA GTPase MukB PF04310.12 KFM60327.1 - 0.013 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 MukB N-terminal AAA_21 PF13304.6 KFM60327.1 - 0.024 14.5 0.5 0.041 13.7 0.5 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFM60327.1 - 0.024 14.3 0.7 0.035 13.8 0.1 1.5 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 KFM60327.1 - 0.058 13.0 0.3 0.081 12.5 0.3 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KFM60327.1 - 0.078 12.7 0.5 0.26 11.0 0.3 1.7 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 KFM60327.1 - 0.12 12.3 0.1 0.89 9.6 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 KFM60327.1 - 0.12 12.4 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 KFM60328.1 - 1e-07 32.6 0.0 1.5e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM60328.1 - 4.4e-07 30.0 0.0 6.2e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KFM60329.1 - 7.4e-20 71.9 0.0 8.9e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM60329.1 - 0.00029 20.8 0.4 0.0011 18.9 0.3 1.8 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFM60329.1 - 0.0084 16.6 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM60329.1 - 0.028 13.7 0.0 0.11 11.8 0.0 1.8 1 1 1 2 2 2 0 Zeta toxin DUF3584 PF12128.8 KFM60329.1 - 0.028 12.0 0.1 0.036 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MMR_HSR1 PF01926.23 KFM60329.1 - 0.031 14.4 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.14 KFM60329.1 - 0.031 14.2 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 KFM60329.1 - 0.033 13.9 0.1 0.073 12.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM60329.1 - 0.044 13.7 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KFM60329.1 - 0.097 13.0 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KFM60329.1 - 0.11 11.4 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.14 KFM60329.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase TsaE PF02367.17 KFM60329.1 - 0.19 11.7 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sad1_UNC PF07738.13 KFM60333.1 - 1.6e-30 105.8 0.0 4.3e-30 104.4 0.0 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal YlqD PF11068.8 KFM60333.1 - 0.16 12.3 2.5 0.48 10.8 2.5 1.8 1 0 0 1 1 1 0 YlqD protein EF-hand_1 PF00036.32 KFM60333.1 - 0.17 11.5 0.1 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 EF hand Myosin_head PF00063.21 KFM60334.1 - 2.2e-107 360.0 5.1 2.2e-107 360.0 5.1 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) MyTH4 PF00784.17 KFM60334.1 - 1.7e-63 211.8 0.0 1.9e-32 112.0 0.0 3.2 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 KFM60334.1 - 3.5e-26 91.9 0.3 7.4e-18 65.1 0.0 4.0 4 0 0 4 4 4 2 FERM central domain FERM_N PF09379.10 KFM60334.1 - 9.3e-11 41.5 0.0 0.00035 20.5 0.0 2.7 2 0 0 2 2 2 2 FERM N-terminal domain IQ PF00612.27 KFM60334.1 - 3e-09 35.9 38.1 0.0015 18.1 2.3 5.4 5 0 0 5 5 5 4 IQ calmodulin-binding motif SH3_2 PF07653.17 KFM60334.1 - 3.9e-06 26.4 0.0 9.6e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFM60334.1 - 4.3e-05 23.3 0.1 0.00022 21.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain RA PF00788.23 KFM60334.1 - 0.00011 22.8 0.0 0.028 15.0 0.0 2.7 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 KFM60334.1 - 0.00013 21.5 0.0 0.0005 19.6 0.0 2.1 2 0 0 2 2 2 1 SH3 domain PID PF00640.23 KFM60334.1 - 0.019 15.0 0.7 0.068 13.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) ASCH PF04266.14 KFM60334.1 - 0.06 13.9 0.0 4.4 7.9 0.0 3.0 2 0 0 2 2 2 0 ASCH domain Myosin_head PF00063.21 KFM60335.1 - 7.7e-87 292.1 0.9 8.4e-87 292.0 0.9 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) ABC_tran PF00005.27 KFM60335.1 - 0.0015 19.1 0.4 0.0031 18.0 0.3 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KFM60335.1 - 0.0024 18.2 0.0 0.005 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM60335.1 - 0.023 15.1 0.0 0.031 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KFM60335.1 - 0.085 11.9 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KFM60335.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Ion_trans_2 PF07885.16 KFM60338.1 - 1.2e-34 118.2 12.9 1.2e-18 66.9 0.7 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFM60338.1 - 2.4e-05 23.7 10.8 0.00089 18.6 0.1 2.5 2 1 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 KFM60338.1 - 0.14 12.0 0.4 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Ligand-gated ion channel XAP5 PF04921.14 KFM60340.1 - 0.14 12.0 1.0 0.16 11.7 1.0 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Spt5_N PF11942.8 KFM60340.1 - 0.46 11.5 9.1 0.71 10.9 9.1 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Bromodomain PF00439.25 KFM60341.1 - 6.2e-64 212.1 17.1 6.8e-22 77.4 1.1 5.3 6 0 0 6 6 6 4 Bromodomain BAH PF01426.18 KFM60341.1 - 2.1e-44 150.3 4.7 7.6e-27 93.6 2.1 2.8 2 0 0 2 2 2 2 BAH domain HMG_box PF00505.19 KFM60341.1 - 1.9e-12 47.4 0.0 4.6e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM60341.1 - 1.6e-07 31.8 0.0 4.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain FOXP-CC PF16159.5 KFM60341.1 - 0.00068 20.2 0.6 0.05 14.2 0.1 2.8 2 0 0 2 2 2 1 FOXP coiled-coil domain RecG_N PF17190.4 KFM60341.1 - 0.046 14.5 0.4 7.2 7.4 0.1 3.3 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF285 PF03382.14 KFM60341.1 - 0.8 9.5 4.6 1.7 8.4 0.2 3.1 3 0 0 3 3 3 0 Mycoplasma protein of unknown function, DUF285 Bromodomain PF00439.25 KFM60342.1 - 4.8e-43 145.1 4.9 1.3e-21 76.4 0.3 2.3 2 0 0 2 2 2 2 Bromodomain DUF2461 PF09365.10 KFM60342.1 - 0.029 14.3 0.2 0.042 13.8 0.2 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) PCI PF01399.27 KFM60342.1 - 0.067 13.7 0.6 0.57 10.7 0.1 2.2 2 1 0 2 2 2 0 PCI domain RRM_1 PF00076.22 KFM60343.1 - 6.2e-87 285.4 5.4 2.4e-23 81.8 0.4 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KFM60343.1 - 9.5e-30 102.6 0.7 9.9e-29 99.3 0.5 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 KFM60343.1 - 1.7e-09 37.4 0.0 0.0012 18.6 0.0 3.7 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFM60343.1 - 3.9e-09 36.4 0.2 0.13 12.3 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFM60343.1 - 1.2e-08 34.6 0.0 0.016 14.8 0.0 4.3 1 1 2 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM60343.1 - 1.9e-05 24.7 1.4 1.4 9.1 0.0 5.2 4 4 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 KFM60343.1 - 0.00027 21.0 0.9 14 5.9 0.0 4.4 4 0 0 4 4 4 1 Limkain b1 SET_assoc PF11767.8 KFM60343.1 - 0.00083 18.9 0.0 17 5.1 0.0 4.3 4 0 0 4 4 4 1 Histone lysine methyltransferase SET associated OB_RNB PF08206.11 KFM60343.1 - 0.0034 17.0 1.9 6.1 6.6 0.1 3.8 4 0 0 4 4 4 2 Ribonuclease B OB domain RRM_3 PF08777.11 KFM60343.1 - 0.0092 16.0 4.8 1.2 9.2 0.2 3.6 3 1 1 4 4 4 2 RNA binding motif HTH_Tnp_Tc3_2 PF01498.18 KFM60344.1 - 2.6e-16 59.6 2.2 5e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60344.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 KFM60345.1 - 3.4e-79 266.7 3.4 4.1e-79 266.4 3.4 1.1 1 0 0 1 1 1 1 Transposase IS4 Homeodomain PF00046.29 KFM60346.1 - 1.6e-20 72.7 0.5 2.2e-20 72.2 0.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM60346.1 - 9.2e-08 31.9 0.5 1.8e-07 30.9 0.1 1.6 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 KFM60346.1 - 0.00014 21.2 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez MerR_1 PF13411.6 KFM60346.1 - 0.078 13.1 0.2 0.24 11.5 0.2 1.8 2 1 0 2 2 2 0 MerR HTH family regulatory protein PAS PF00989.25 KFM60347.1 - 3.1e-10 40.1 0.0 3.5e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFM60347.1 - 6.9e-10 39.0 0.2 2.6e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 KFM60347.1 - 8.5e-10 38.8 0.0 0.00089 19.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFM60347.1 - 3.2e-06 27.3 0.0 0.00025 21.3 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_2 PF08446.11 KFM60347.1 - 0.00012 22.7 0.0 0.006 17.2 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 KFM60347.1 - 0.00012 22.3 0.0 0.0089 16.3 0.0 2.2 2 0 0 2 2 2 1 PAS fold HIF-1a_CTAD PF08778.10 KFM60348.1 - 2.6e-09 36.5 0.0 5.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.8 KFM60348.1 - 0.0026 17.1 1.6 0.0026 17.1 1.6 2.5 2 0 0 2 2 2 1 Hypoxia-inducible factor-1 Menin PF05053.13 KFM60348.1 - 0.11 10.9 1.1 0.15 10.4 1.1 1.2 1 0 0 1 1 1 0 Menin DUF3522 PF12036.8 KFM60349.1 - 2.6e-62 210.5 13.2 5e-62 209.6 13.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) LYRIC PF15686.5 KFM60349.1 - 0.005 16.5 0.1 0.0088 15.6 0.1 1.3 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family FF PF01846.19 KFM60350.1 - 1.2e-44 150.2 26.0 7.2e-12 45.3 1.1 5.2 5 0 0 5 5 5 4 FF domain WW PF00397.26 KFM60350.1 - 2.3e-23 81.9 23.4 3.1e-09 36.8 2.4 3.8 4 0 0 4 4 4 3 WW domain Glyco_hyd_101C PF17451.2 KFM60350.1 - 0.00011 22.5 10.0 0.87 9.9 0.3 4.3 3 2 0 3 3 3 3 Glycosyl hydrolase 101 beta sandwich domain DDE_3 PF13358.6 KFM60351.1 - 0.0031 17.3 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_8 PF01501.20 KFM60352.1 - 7e-14 52.0 0.3 1.1e-13 51.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Borrelia_rep PF03183.13 KFM60353.1 - 0.26 11.3 1.2 0.46 10.6 1.2 1.4 1 0 0 1 1 1 0 Borrelia repeat protein Glyco_hydro_88 PF07470.13 KFM60354.1 - 0.02 14.0 0.1 0.02 14.0 0.1 1.0 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KFM60355.1 - 0.037 13.5 0.7 0.052 13.0 0.6 1.4 1 1 1 2 2 2 0 D-glucuronyl C5-epimerase C-terminus ECH_1 PF00378.20 KFM60356.1 - 8.8e-48 162.8 0.0 1.1e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM60356.1 - 8e-14 51.9 0.0 1.1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SYCP2_SLD PF18584.1 KFM60356.1 - 0.013 15.7 2.4 0.037 14.2 0.0 2.6 3 0 0 3 3 3 0 Synaptonemal complex 2 Spt16M-like domain DcrB PF08786.11 KFM60356.1 - 0.08 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 DcrB DUF5470 PF17564.2 KFM60356.1 - 0.084 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5470) FPL PF09758.9 KFM60356.1 - 0.11 12.5 1.5 0.15 12.1 0.6 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein RVT_1 PF00078.27 KFM60357.1 - 0.0023 17.5 0.2 0.0023 17.5 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IRK_C PF17655.1 KFM60358.1 - 3.2e-72 241.8 0.0 4.6e-72 241.3 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFM60358.1 - 4.5e-61 204.8 2.6 6.4e-61 204.3 2.6 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFM60358.1 - 0.0016 18.3 1.8 0.0036 17.2 1.8 1.6 1 1 0 1 1 1 1 Ion channel Ribosomal_L33 PF00471.20 KFM60359.1 - 5.8e-07 29.8 0.1 7e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 HTH_Tnp_Tc3_2 PF01498.18 KFM60360.1 - 4.3e-16 58.9 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60360.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60360.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60360.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60360.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Sacchrp_dh_NADP PF03435.18 KFM60362.1 - 9.7e-15 55.0 0.1 1.5e-14 54.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFM60362.1 - 0.012 15.1 0.1 0.023 14.1 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Mannosyl_trans3 PF11051.8 KFM60362.1 - 0.13 11.6 0.2 0.2 11.0 0.2 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative NUDIX PF00293.28 KFM60363.1 - 3.7e-17 62.6 0.0 6.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 KFM60363.1 - 2.3e-09 37.5 0.0 5.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Dcp2, box A domain ASC PF00858.24 KFM60364.1 - 9e-11 41.4 0.4 9.5e-11 41.3 0.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel OATP PF03137.20 KFM60366.1 - 0.28 9.4 4.4 0.32 9.2 4.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Myelin_PLP PF01275.19 KFM60366.1 - 2.3 8.0 7.3 13 5.5 7.3 1.9 1 1 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) DUF4371 PF14291.6 KFM60367.1 - 4.2e-10 39.7 0.1 1.3e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM60367.1 - 0.0028 17.2 0.8 0.0028 17.2 0.8 2.3 2 1 0 2 2 2 1 Zinc-finger C2H2-type DDE_3 PF13358.6 KFM60368.1 - 5e-16 58.8 0.0 9.1e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60368.1 - 6e-14 52.1 3.7 1.8e-13 50.5 1.4 2.3 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 KFM60368.1 - 4.8e-05 23.4 2.8 0.0021 18.2 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.18 KFM60368.1 - 0.00015 21.6 0.1 0.00029 20.7 0.1 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 KFM60368.1 - 0.00081 20.0 5.5 0.00081 20.0 5.5 3.2 3 1 0 3 3 3 1 Homeodomain-like domain HTH_37 PF13744.6 KFM60368.1 - 0.029 14.3 0.3 3.8 7.5 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM60368.1 - 0.055 13.3 6.2 0.57 10.0 0.1 3.2 2 1 0 2 2 2 0 Homeodomain-like domain HTH_22 PF13309.6 KFM60368.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_7 PF02796.15 KFM60368.1 - 0.17 12.0 3.3 0.99 9.5 1.8 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM60368.1 - 0.26 11.3 1.8 3 7.9 0.2 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_38 PF13936.6 KFM60368.1 - 0.28 11.0 0.1 0.28 11.0 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 KFM60368.1 - 0.54 10.2 4.0 0.87 9.5 0.1 2.8 3 0 0 3 3 3 0 MarR family HTH_Tnp_Tc3_2 PF01498.18 KFM60369.1 - 2.1e-16 59.9 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60369.1 - 9e-14 51.4 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60370.1 - 2e-16 60.0 2.2 4.3e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60370.1 - 9.1e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4922 PF16269.5 KFM60372.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) HTH_Tnp_Tc3_2 PF01498.18 KFM60374.1 - 2.1e-16 59.9 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60374.1 - 7.8e-14 51.6 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60375.1 - 2.3e-16 59.8 2.2 4.9e-16 58.7 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60375.1 - 9.9e-13 48.1 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease AT_hook PF02178.19 KFM60376.1 - 0.0023 17.6 0.6 0.0023 17.6 0.6 2.4 3 0 0 3 3 3 1 AT hook motif RNase_PH PF01138.21 KFM60377.1 - 4.6e-22 78.9 0.0 5.3e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 AAA_11 PF13086.6 KFM60378.1 - 4.9e-25 88.8 0.3 2.1e-24 86.7 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KFM60378.1 - 9e-18 64.6 0.5 2.2e-17 63.3 0.5 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM60378.1 - 1e-09 38.9 0.0 5.9e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM60378.1 - 9.1e-08 32.0 0.0 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KFM60378.1 - 0.016 15.3 0.1 0.042 13.8 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFM60378.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KFM60378.1 - 0.097 12.2 0.1 0.3 10.5 0.1 2.0 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain 60KD_IMP PF02096.20 KFM60380.1 - 4.7e-18 65.6 1.5 6e-18 65.3 1.5 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein CPSF_A PF03178.15 KFM60381.1 - 1.6e-94 316.8 0.0 3.1e-94 315.9 0.0 1.5 2 0 0 2 2 2 1 CPSF A subunit region DDE_3 PF13358.6 KFM60382.1 - 1.6e-12 47.4 0.0 4.4e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60382.1 - 2.1e-09 37.5 0.0 3.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Transposase Pyr_redox_2 PF07992.14 KFM60384.1 - 7.2e-22 78.0 0.1 8.2e-22 77.8 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM60384.1 - 7.6e-06 25.2 3.6 6e-05 22.3 3.1 2.2 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KFM60384.1 - 0.00011 21.0 0.2 0.00091 18.0 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KFM60384.1 - 0.0002 20.7 2.4 0.098 11.9 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM60384.1 - 0.0016 17.7 0.0 0.0067 15.6 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KFM60384.1 - 0.0025 17.1 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KFM60384.1 - 0.0056 16.0 0.3 0.0086 15.3 0.3 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KFM60384.1 - 0.0099 15.3 3.7 0.01 15.2 3.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KFM60384.1 - 0.015 14.9 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM60384.1 - 0.042 14.1 1.6 0.1 12.9 1.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFM60384.1 - 0.075 12.1 2.3 0.11 11.6 2.3 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_dim PF02852.22 KFM60385.1 - 1.1e-29 102.9 0.0 1.9e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.14 KFM60385.1 - 4.7e-19 68.7 0.0 6e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM60385.1 - 0.0004 20.9 0.0 0.00088 19.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyoxalase PF00903.25 KFM60386.1 - 2.5e-27 95.6 0.6 2.2e-16 60.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFM60386.1 - 1.5e-15 57.4 0.0 1.7e-08 34.7 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFM60386.1 - 7.7e-11 42.4 0.0 1.1e-05 25.6 0.0 3.1 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KFM60386.1 - 0.00041 20.6 0.0 0.0038 17.4 0.1 2.1 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF1907 PF08925.11 KFM60388.1 - 1.6e-119 398.5 0.0 1.8e-119 398.4 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) GPCR_chapero_1 PF11904.8 KFM60389.1 - 3.7e-83 279.5 0.0 4.2e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 GPCR-chaperone MH2 PF03166.14 KFM60390.1 - 1.4e-76 256.9 0.0 2e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFM60390.1 - 1.3e-39 134.6 0.4 2.5e-39 133.6 0.4 1.5 1 0 0 1 1 1 1 MH1 domain DUF4667 PF15700.5 KFM60390.1 - 2.8 8.0 7.1 6.6 6.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4667) Leo1 PF04004.13 KFM60391.1 - 1.9e-50 170.9 0.0 1.9e-50 170.9 0.0 4.6 3 2 0 3 3 3 1 Leo1-like protein CARD PF00619.21 KFM60392.1 - 0.00033 20.6 0.3 0.00054 19.9 0.3 1.4 1 0 0 1 1 1 1 Caspase recruitment domain Red1 PF07964.11 KFM60392.1 - 0.015 13.5 0.2 0.016 13.5 0.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 PhosphMutase PF10143.9 KFM60392.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase HTH_Tnp_Tc3_2 PF01498.18 KFM60394.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60394.1 - 7.4e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GRP PF07172.11 KFM60397.1 - 0.00082 20.0 2.3 0.00082 20.0 2.3 3.3 1 1 2 3 3 3 1 Glycine rich protein family MIR PF02815.19 KFM60398.1 - 7.2e-13 48.8 0.2 7.3e-12 45.5 0.2 2.0 1 1 0 1 1 1 1 MIR domain OrsD PF12013.8 KFM60402.1 - 0.00015 22.2 1.5 0.001 19.5 0.3 2.7 2 1 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4718 PF15842.5 KFM60402.1 - 0.0082 16.0 4.6 0.0082 16.0 1.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4718) C6_DPF PF10170.9 KFM60402.1 - 0.067 13.6 0.5 0.2 12.0 0.5 1.8 1 0 0 1 1 1 0 Cysteine-rich domain Glyco_hydro_39 PF01229.17 KFM60404.1 - 5.2e-61 206.7 0.9 5.8e-61 206.6 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_39 PF01229.17 KFM60405.1 - 2e-07 30.0 0.0 2.3e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_39 PF01229.17 KFM60406.1 - 9.6e-05 21.2 0.0 0.00012 20.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 fn3 PF00041.21 KFM60406.1 - 0.0026 18.0 0.1 0.0053 17.1 0.0 1.5 2 0 0 2 2 2 1 Fibronectin type III domain Homeodomain PF00046.29 KFM60407.1 - 5.9e-22 77.3 4.5 5.4e-21 74.2 5.7 1.8 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 KFM60407.1 - 0.05 13.1 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Forkhead PF00250.18 KFM60408.1 - 5.1e-29 100.4 0.0 8.4e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain HTH_Tnp_Tc3_2 PF01498.18 KFM60410.1 - 4.2e-16 58.9 3.5 5.7e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60410.1 - 9.3e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60410.1 - 6.9e-08 32.1 0.6 7.1e-07 28.9 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60410.1 - 0.0027 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60410.1 - 2.4 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 KFM60411.1 - 1.4e-80 262.4 57.7 5.7e-10 39.2 0.3 10.1 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60411.1 - 5.8e-51 168.2 75.3 8.5e-07 29.1 0.7 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60411.1 - 2.6e-39 130.5 71.5 0.0001 22.8 0.7 10.1 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFM60411.1 - 6e-27 93.2 70.1 0.00013 22.3 0.7 9.8 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60411.1 - 4.6e-20 71.4 43.4 0.016 15.5 0.5 9.3 9 0 0 9 9 9 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM60411.1 - 2.9e-19 68.6 65.0 0.00051 20.0 0.4 10.2 10 1 0 10 10 10 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM60411.1 - 5e-15 54.9 47.2 0.00095 18.9 0.5 9.4 10 0 0 10 10 9 7 C2H2-type zinc-finger domain BolA PF01722.18 KFM60411.1 - 3.4e-09 36.9 5.4 0.98 9.7 0.0 7.4 1 1 3 6 6 6 2 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM60411.1 - 2.6e-08 33.8 29.5 0.71 10.0 1.0 9.6 2 1 8 10 10 10 1 Sec23/Sec24 zinc finger Tox-HNH-HHH PF15637.6 KFM60411.1 - 1e-07 32.0 0.5 0.024 14.8 0.0 4.3 1 1 3 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_11 PF16622.5 KFM60411.1 - 1.8e-07 30.8 51.8 0.052 13.3 0.5 9.4 10 0 0 10 10 9 5 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFM60411.1 - 1e-06 28.5 35.1 1.4 8.9 0.2 8.9 3 3 6 9 9 9 3 C2H2 type zinc-finger (1 copy) TRAF6_Z2 PF18048.1 KFM60411.1 - 1.3e-06 28.4 32.5 0.91 9.7 1.5 8.9 9 0 0 9 9 9 3 TNF receptor-associated factor 6 zinc finger 2 GAGA PF09237.11 KFM60411.1 - 5.9e-06 26.0 16.5 0.43 10.4 0.0 6.6 2 2 6 8 8 8 3 GAGA factor DUF3396 PF11876.8 KFM60411.1 - 3.4e-05 23.4 0.0 0.0018 17.8 0.0 2.8 2 1 0 3 3 3 1 Protein of unknown function (DUF3396) zf-MYST PF17772.1 KFM60411.1 - 0.00019 21.0 54.5 0.27 10.9 0.2 9.7 3 3 7 10 10 10 4 MYST family zinc finger domain zf_UBZ PF18439.1 KFM60411.1 - 0.0062 16.1 40.1 0.33 10.6 0.2 8.8 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM60411.1 - 0.035 14.4 57.9 1.4 9.3 0.5 9.0 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 KFM60411.1 - 0.068 13.3 47.5 1.6 8.9 1.9 9.1 1 1 7 9 9 9 0 KIAA1045 RING finger zf-FPG_IleRS PF06827.14 KFM60411.1 - 0.081 12.8 23.6 46 4.0 0.0 8.4 9 0 0 9 9 9 0 Zinc finger found in FPG and IleRS Nore1-SARAH PF16517.5 KFM60411.1 - 0.1 12.5 0.3 6.2 6.8 0.1 3.3 3 0 0 3 3 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain C1_1 PF00130.22 KFM60411.1 - 0.17 11.8 45.3 2.6 8.0 1.9 8.3 1 1 5 7 7 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFM60411.1 - 0.32 11.8 41.0 0.64 10.8 1.3 5.1 1 1 3 5 5 4 0 zinc-ribbon family DUF2256 PF10013.9 KFM60411.1 - 0.33 11.1 41.8 4.1 7.6 0.4 9.3 10 0 0 10 10 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-trcl PF13451.6 KFM60411.1 - 0.8 9.6 39.8 2.9 7.9 0.2 8.9 8 1 0 8 8 8 0 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFM60411.1 - 1.3 9.3 42.5 1.3 9.2 1.5 7.0 3 2 5 8 8 8 0 Zinc ribbon domain zf-DBF PF07535.12 KFM60411.1 - 1.8 8.7 41.6 12 6.1 0.1 8.6 9 0 0 9 9 8 0 DBF zinc finger Zn_ribbon_SprT PF17283.2 KFM60411.1 - 8.3 6.4 36.9 1.4 8.9 1.1 6.9 7 1 1 8 8 8 0 SprT-like zinc ribbon domain zf-H2C2_2 PF13465.6 KFM60412.1 - 2.3e-13 49.9 5.6 7e-08 32.6 0.5 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60412.1 - 4.8e-10 39.3 8.6 2.1e-06 27.9 2.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60412.1 - 2.3e-08 34.2 6.8 5e-05 23.8 1.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM60412.1 - 1e-05 25.4 3.6 0.014 15.4 0.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM60412.1 - 2.8e-05 24.3 5.2 0.0062 16.9 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60412.1 - 6.5e-05 23.1 4.4 0.074 13.4 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF2757 PF10955.8 KFM60412.1 - 0.0011 19.1 1.5 0.76 10.1 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2757) zf-H2C2_5 PF13909.6 KFM60412.1 - 0.02 14.7 0.8 0.02 14.7 0.8 3.1 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KFM60412.1 - 0.02 15.2 1.0 0.021 15.1 1.0 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-MYST PF17772.1 KFM60412.1 - 0.023 14.3 3.0 0.69 9.6 0.3 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain zf-Di19 PF05605.12 KFM60412.1 - 0.032 14.5 1.0 0.032 14.5 1.0 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KFM60412.1 - 0.089 12.6 1.4 0.15 11.9 0.2 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFM60412.1 - 0.095 13.1 0.8 0.095 13.1 0.8 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C4_ClpX PF06689.13 KFM60412.1 - 0.37 10.7 5.8 0.34 10.8 0.4 2.1 1 1 1 2 2 2 0 ClpX C4-type zinc finger zf_UBZ PF18439.1 KFM60412.1 - 0.67 9.6 5.3 0.38 10.4 0.5 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KFM60413.1 - 1.6e-19 69.4 13.1 1.6e-07 31.4 0.2 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60413.1 - 4.6e-18 64.6 21.7 2e-06 27.9 1.1 3.5 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60413.1 - 7.9e-15 54.3 19.9 8.5e-05 23.1 0.7 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KFM60413.1 - 4.1e-12 46.1 19.2 0.00014 22.1 1.1 3.3 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60413.1 - 4.9e-09 36.2 13.7 0.0021 18.3 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM60413.1 - 1.7e-06 27.7 13.5 0.027 14.2 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM60413.1 - 2.2e-05 24.3 16.2 0.12 12.4 0.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM60413.1 - 0.00026 21.0 8.6 0.32 11.1 0.0 3.2 2 1 1 3 3 3 1 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM60413.1 - 0.0013 18.2 13.0 0.79 9.4 0.2 3.1 1 1 2 3 3 3 2 MYST family zinc finger domain zf-C2H2_2 PF12756.7 KFM60413.1 - 0.0016 18.8 18.6 0.45 10.9 0.6 3.1 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFM60413.1 - 0.0018 18.5 0.1 0.96 9.8 0.0 2.8 1 1 1 2 2 2 1 BolA-like protein TRAF6_Z2 PF18048.1 KFM60413.1 - 0.0019 18.2 13.5 0.056 13.5 0.9 3.6 4 0 0 4 4 3 2 TNF receptor-associated factor 6 zinc finger 2 Zn-C2H2_12 PF18112.1 KFM60413.1 - 0.0033 17.8 11.7 0.42 11.1 0.6 3.7 3 0 0 3 3 3 2 Autophagy receptor zinc finger-C2H2 domain Tox-HNH-HHH PF15637.6 KFM60413.1 - 0.0067 16.6 0.0 0.034 14.3 0.0 1.9 1 1 0 1 1 1 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif Metallothio_Pro PF02069.16 KFM60413.1 - 0.015 15.5 9.6 6.8 7.0 0.1 3.1 1 1 2 3 3 3 0 Prokaryotic metallothionein C1_1 PF00130.22 KFM60413.1 - 0.031 14.2 14.9 4.6 7.2 4.8 3.1 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM60413.1 - 0.033 14.0 2.4 0.94 9.3 0.0 2.8 1 1 2 3 3 3 0 GAGA factor zf-C2H2_9 PF16293.5 KFM60413.1 - 0.038 13.8 10.8 2.6 7.9 0.2 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 KFM60413.1 - 0.058 13.5 12.8 1.4 9.1 0.1 3.1 1 1 2 3 3 3 0 KIAA1045 RING finger PyrI_C PF02748.15 KFM60413.1 - 0.23 11.4 12.2 2.3 8.2 0.2 3.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_UBZ PF18439.1 KFM60413.1 - 0.3 10.7 10.5 2.3 7.9 1.5 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PHD PF00628.29 KFM60413.1 - 0.31 11.0 12.4 7.4 6.6 10.3 2.4 2 1 0 2 2 2 0 PHD-finger zf-C2H2_8 PF15909.5 KFM60413.1 - 0.36 11.1 10.9 0.16 12.2 2.7 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KFM60413.1 - 0.49 10.6 9.5 12 6.1 4.0 3.1 1 1 2 3 3 3 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 KFM60413.1 - 0.51 10.1 14.9 6.1 6.7 0.2 3.6 3 0 0 3 3 3 0 A2L zinc ribbon domain DUF2256 PF10013.9 KFM60413.1 - 0.73 10.0 11.7 8.9 6.5 0.1 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) SVS_QK PF10578.9 KFM60413.1 - 0.74 10.5 4.2 8.2 7.3 0.6 2.4 2 0 0 2 2 2 0 Seminal vesicle protein repeat FYVE_2 PF02318.16 KFM60413.1 - 1 9.6 13.7 1.1 9.5 2.8 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger zf-C2H2_11 PF16622.5 KFM60413.1 - 1.5 8.6 24.1 0.2 11.4 2.9 3.7 4 0 0 4 4 3 0 zinc-finger C2H2-type zf-CCHC_2 PF13696.6 KFM60413.1 - 1.5 8.7 12.0 16 5.5 2.6 3.4 3 0 0 3 3 3 0 Zinc knuckle DUF629 PF04780.12 KFM60413.1 - 4 5.9 15.0 6.3 5.2 3.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF629) FYVE PF01363.21 KFM60413.1 - 5.2 7.3 15.0 4.8 7.4 11.8 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-BED PF02892.15 KFM60413.1 - 6.1 7.0 15.9 1.8 8.6 1.1 3.0 1 1 2 3 3 3 0 BED zinc finger zf-H2C2_2 PF13465.6 KFM60414.1 - 1.6e-91 297.0 73.6 9.8e-10 38.4 0.4 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60414.1 - 1.7e-61 201.4 83.4 4e-06 27.0 1.5 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60414.1 - 4.5e-45 148.4 80.6 0.00019 22.0 1.2 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM60414.1 - 1.8e-28 98.0 81.2 0.00093 19.5 0.7 11.3 11 0 0 11 11 11 11 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM60414.1 - 6.2e-20 70.6 62.6 0.036 13.8 0.2 12.3 12 0 0 12 12 12 10 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM60414.1 - 8.7e-17 60.9 60.9 0.019 15.2 0.2 11.2 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM60414.1 - 6.5e-15 54.7 70.1 0.011 15.8 1.0 11.7 11 0 0 11 11 11 7 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM60414.1 - 2.5e-11 43.1 66.8 0.08 12.7 0.7 10.8 11 0 0 11 11 11 8 zinc-finger C2H2-type BolA PF01722.18 KFM60414.1 - 2.4e-10 40.5 13.8 0.41 11.0 0.4 7.0 3 2 4 7 7 7 3 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM60414.1 - 1.5e-08 34.5 29.3 1.4 9.0 0.0 10.5 8 3 3 11 11 11 2 Sec23/Sec24 zinc finger Tox-HNH-HHH PF15637.6 KFM60414.1 - 1.6e-05 25.0 0.3 5.9 7.1 0.0 4.0 2 2 1 4 4 4 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif GAGA PF09237.11 KFM60414.1 - 7.8e-05 22.4 15.6 6 6.8 0.0 7.9 3 2 6 9 9 9 1 GAGA factor zinc_ribbon_15 PF17032.5 KFM60414.1 - 0.0017 19.0 40.2 1 10.2 2.1 5.9 1 1 5 7 7 7 4 zinc-ribbon family Zf_RING PF16744.5 KFM60414.1 - 0.0029 17.7 50.1 4.6 7.4 0.1 10.5 1 1 9 10 10 10 1 KIAA1045 RING finger zf-MYST PF17772.1 KFM60414.1 - 0.0039 16.7 59.1 0.8 9.4 0.3 10.6 1 1 10 11 11 11 4 MYST family zinc finger domain zf-C2H2_9 PF16293.5 KFM60414.1 - 0.02 14.7 48.2 3.3 7.6 0.2 10.4 5 5 6 11 11 11 0 C2H2 type zinc-finger (1 copy) DUF3048 PF11258.8 KFM60414.1 - 0.02 15.0 0.0 55 3.8 0.0 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF3048) N-terminal domain DUF4499 PF14934.6 KFM60414.1 - 0.051 13.9 15.6 5.3 7.4 0.2 6.8 2 2 8 10 10 9 0 Domain of unknown function (DUF4499) zf-RRPl_C4 PF17026.5 KFM60414.1 - 0.053 13.6 47.7 0.19 11.8 6.1 5.3 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn_ribbon_SprT PF17283.2 KFM60414.1 - 0.064 13.2 0.3 0.064 13.2 0.3 7.1 5 2 3 8 8 6 0 SprT-like zinc ribbon domain C1_4 PF07975.12 KFM60414.1 - 0.12 12.6 53.0 4.2 7.7 3.6 8.2 2 2 8 10 10 10 0 TFIIH C1-like domain zf-C2H2_2 PF12756.7 KFM60414.1 - 0.14 12.5 66.9 2.2 8.7 0.7 10.2 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 KFM60414.1 - 0.36 11.0 49.0 10 6.3 0.1 10.7 10 1 1 11 11 11 0 DBF zinc finger zf-C2HC_2 PF13913.6 KFM60414.1 - 0.65 10.0 0.1 0.65 10.0 0.1 10.8 11 0 0 11 11 10 0 zinc-finger of a C2HC-type Mga PF05043.13 KFM60414.1 - 0.76 10.4 4.6 5.4 7.7 0.1 3.4 3 2 0 3 3 2 0 Mga helix-turn-helix domain zf_UBZ PF18439.1 KFM60414.1 - 2 8.1 45.2 6.6 6.4 0.1 10.6 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 KFM60414.1 - 6.1 7.1 43.7 6.8 6.9 0.0 10.4 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) Scramblase PF03803.15 KFM60414.1 - 8.1 5.7 10.6 1.3 8.2 1.9 2.9 1 1 3 4 4 4 0 Scramblase zf-H2C2_2 PF13465.6 KFM60415.1 - 4.2e-62 204.0 48.4 4.6e-09 36.3 0.7 9.1 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60415.1 - 4.1e-44 146.6 70.8 2e-06 27.9 1.6 9.2 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60415.1 - 1.4e-35 118.9 67.7 0.00022 21.8 0.9 9.2 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM60415.1 - 2.8e-19 68.8 67.5 0.0075 16.6 1.8 9.3 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM60415.1 - 6.8e-11 41.9 59.6 0.084 12.9 0.9 9.3 9 0 0 9 9 9 6 C2H2-type zinc finger BolA PF01722.18 KFM60415.1 - 2.6e-08 34.0 1.8 2 8.8 0.1 6.2 1 1 5 6 6 6 1 BolA-like protein GAGA PF09237.11 KFM60415.1 - 3.4e-08 33.2 11.4 0.43 10.4 0.2 6.2 3 3 3 6 6 6 3 GAGA factor zf-C2HC_2 PF13913.6 KFM60415.1 - 9e-07 28.7 41.3 1.7 8.6 0.1 9.6 9 0 0 9 9 9 4 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM60415.1 - 1.4e-05 25.1 31.6 3.8 7.6 0.2 8.7 5 2 4 9 9 9 1 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KFM60415.1 - 2.3e-05 24.5 58.8 0.15 12.4 0.1 9.2 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding Tox-HNH-HHH PF15637.6 KFM60415.1 - 2.3e-05 24.5 0.2 0.18 12.0 0.0 3.2 2 1 2 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif TRAF6_Z2 PF18048.1 KFM60415.1 - 2.8e-05 24.1 35.6 0.057 13.5 1.0 7.5 8 0 0 8 8 8 2 TNF receptor-associated factor 6 zinc finger 2 C1_4 PF07975.12 KFM60415.1 - 0.0003 20.9 53.8 0.11 12.7 5.5 7.3 1 1 6 8 8 8 4 TFIIH C1-like domain Zf_RING PF16744.5 KFM60415.1 - 0.0025 17.9 48.6 2.1 8.5 1.0 8.8 2 2 7 9 9 9 2 KIAA1045 RING finger Baculo_IE-1 PF05290.11 KFM60415.1 - 0.0026 17.7 35.6 3.8 7.4 0.1 8.4 1 1 4 6 6 6 1 Baculovirus immediate-early protein (IE-0) UPF0728 PF15092.6 KFM60415.1 - 0.0088 15.9 17.2 2.4 8.0 0.2 6.2 2 1 4 7 7 7 1 Uncharacterised protein family UPF0728 DUF4499 PF14934.6 KFM60415.1 - 0.024 14.9 11.9 3.1 8.2 0.2 6.0 2 2 3 7 7 7 0 Domain of unknown function (DUF4499) zf-MYST PF17772.1 KFM60415.1 - 0.041 13.5 51.9 0.79 9.4 0.4 8.8 2 1 7 9 9 9 0 MYST family zinc finger domain PHD PF00628.29 KFM60415.1 - 0.14 12.0 41.8 0.9 9.5 1.3 5.8 3 1 3 6 6 6 0 PHD-finger C1_1 PF00130.22 KFM60415.1 - 0.16 11.9 47.0 0.85 9.5 4.7 6.7 1 1 6 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3837 PF12939.7 KFM60415.1 - 0.21 12.0 4.2 5.2 7.5 0.1 3.7 3 2 1 4 4 4 0 Domain of unknown function (DUF3837) zinc_ribbon_15 PF17032.5 KFM60415.1 - 0.67 10.7 40.0 1.9 9.3 3.9 4.9 1 1 6 7 7 7 0 zinc-ribbon family Thioredoxin_16 PF18569.1 KFM60415.1 - 0.81 9.9 6.4 14 5.9 0.1 3.8 2 2 0 3 3 3 0 Thioredoxin-like domain zf-C2H2_9 PF16293.5 KFM60415.1 - 1.7 8.5 32.3 16 5.4 0.5 8.0 3 3 6 9 9 9 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 KFM60415.1 - 5.7 7.1 32.8 3.8e+03 -2.0 11.6 5.4 1 1 1 2 2 1 0 Double zinc ribbon DrsE PF02635.15 KFM60415.1 - 7.5 7.0 6.3 47 4.4 0.2 4.0 4 1 1 5 5 5 0 DsrE/DsrF-like family zf-C2H2_2 PF12756.7 KFM60415.1 - 8 6.9 51.9 1.6 9.2 0.5 7.7 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) DDE_Tnp_4 PF13359.6 KFM60416.1 - 1.8e-14 53.7 0.0 2.2e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM60416.1 - 0.00035 20.2 0.0 0.00041 20.0 0.0 1.2 1 1 0 1 1 1 1 Plant transposon protein DUF478 PF04334.12 KFM60416.1 - 0.099 12.7 0.0 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF478) zf-H2C2_2 PF13465.6 KFM60417.1 - 2.3e-53 176.3 44.5 1.3e-09 38.0 0.4 7.7 8 1 0 8 8 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60417.1 - 5.5e-37 124.2 59.6 2.2e-05 24.6 2.5 8.0 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60417.1 - 7.8e-28 94.8 58.8 0.00022 21.8 2.5 8.0 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.7 KFM60417.1 - 3.1e-20 71.8 63.5 0.00058 20.2 1.5 7.9 8 0 0 8 8 8 7 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM60417.1 - 3.1e-12 46.0 29.5 0.02 14.7 0.1 8.3 8 0 0 8 8 8 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM60417.1 - 1.6e-10 40.7 56.7 0.081 13.0 3.0 7.7 7 0 0 7 7 7 7 C2H2-type zinc finger BolA PF01722.18 KFM60417.1 - 5e-10 39.5 2.6 0.37 11.1 0.0 5.2 1 1 3 5 5 5 2 BolA-like protein Zf_RING PF16744.5 KFM60417.1 - 2.4e-09 37.1 38.8 0.13 12.4 0.9 7.0 1 1 5 6 6 6 4 KIAA1045 RING finger zf-C2H2_11 PF16622.5 KFM60417.1 - 6.1e-07 29.1 46.7 0.012 15.3 1.0 8.0 8 0 0 8 8 8 5 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM60417.1 - 7.2e-06 26.2 50.9 0.052 13.8 0.1 7.9 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM60417.1 - 1.1e-05 25.4 21.2 0.32 11.1 0.1 7.0 2 1 5 7 7 7 2 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM60417.1 - 3.4e-05 23.6 28.6 0.84 9.6 0.4 7.7 7 0 0 7 7 7 2 zinc-finger of a C2HC-type C1_4 PF07975.12 KFM60417.1 - 0.00052 20.2 42.6 2.1 8.7 1.2 6.4 1 1 6 7 7 7 2 TFIIH C1-like domain GAGA PF09237.11 KFM60417.1 - 0.0008 19.2 17.7 0.31 10.9 0.1 5.9 1 1 6 7 7 7 2 GAGA factor DUF4825 PF16107.5 KFM60417.1 - 0.00088 19.4 0.2 3.5 7.8 0.0 4.1 2 2 3 5 5 5 1 Domain of unknown function (DUF4825) TRAF6_Z2 PF18048.1 KFM60417.1 - 0.0011 19.0 43.1 0.044 13.9 0.7 7.0 8 0 0 8 8 7 3 TNF receptor-associated factor 6 zinc finger 2 C1_1 PF00130.22 KFM60417.1 - 0.03 14.2 43.5 0.37 10.7 4.7 6.0 1 1 5 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Complex1_49kDa PF00346.19 KFM60417.1 - 0.036 13.2 0.3 1.1 8.2 0.0 2.6 2 1 1 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf_UBZ PF18439.1 KFM60417.1 - 0.041 13.5 37.7 1.7 8.3 0.2 7.3 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger GATase_2 PF00310.21 KFM60417.1 - 0.063 12.0 1.0 0.19 10.4 0.1 1.8 1 1 1 2 2 2 0 Glutamine amidotransferases class-II DUF4499 PF14934.6 KFM60417.1 - 0.082 13.3 8.7 2.3 8.6 0.2 4.7 1 1 5 6 6 6 0 Domain of unknown function (DUF4499) TAFII28 PF04719.14 KFM60417.1 - 0.14 12.3 0.0 22 5.2 0.0 2.7 2 1 0 2 2 2 0 hTAFII28-like protein conserved region PHD PF00628.29 KFM60417.1 - 0.19 11.6 39.0 8.8 6.3 6.7 5.3 3 2 2 5 5 5 0 PHD-finger zf-trcl PF13451.6 KFM60417.1 - 0.2 11.6 26.7 1.7 8.6 0.2 6.9 7 0 0 7 7 7 0 Probable zinc-ribbon domain FYVE PF01363.21 KFM60417.1 - 0.22 11.7 40.1 1.4 9.1 8.1 4.8 1 1 3 4 4 4 0 FYVE zinc finger DUF3837 PF12939.7 KFM60417.1 - 0.35 11.3 5.2 2.8 8.4 0.3 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF3837) zf-MYST PF17772.1 KFM60417.1 - 1.8 8.3 43.2 0.52 9.9 0.4 6.9 2 2 5 7 7 7 0 MYST family zinc finger domain Viral_cys_rich PF08008.12 KFM60417.1 - 3.2 7.9 12.5 3.6 7.7 0.5 3.8 1 1 4 5 5 5 0 Viral cysteine rich zf-DBF PF07535.12 KFM60417.1 - 3.2 7.9 42.4 8 6.7 0.6 7.1 7 0 0 7 7 7 0 DBF zinc finger C1_2 PF03107.16 KFM60417.1 - 4.3 7.7 46.0 27 5.2 4.2 6.9 1 1 5 6 6 6 0 C1 domain zinc_ribbon_15 PF17032.5 KFM60417.1 - 5.2 7.9 35.0 3.7 8.4 3.0 4.1 1 1 3 4 4 4 0 zinc-ribbon family Scramblase PF03803.15 KFM60417.1 - 7.8 5.7 8.0 3.1 7.0 0.8 2.1 1 1 1 2 2 2 0 Scramblase Zn-C2H2_12 PF18112.1 KFM60417.1 - 7.9 7.1 42.0 2.3 8.8 0.4 7.5 7 0 0 7 7 7 0 Autophagy receptor zinc finger-C2H2 domain AD PF09793.9 KFM60417.1 - 9.3 6.5 6.9 1.3e+02 2.8 0.0 4.3 4 1 1 5 5 5 0 Anticodon-binding domain DDE_Tnp_1_7 PF13843.6 KFM60418.1 - 7.3e-67 226.1 1.0 8.4e-56 189.8 0.3 2.1 1 1 1 2 2 2 2 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM60418.1 - 0.0011 18.7 0.2 0.003 17.2 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain zf-CCHC PF00098.23 KFM60419.1 - 4.5e-05 23.3 3.5 4.5e-05 23.3 3.5 3.5 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.6 KFM60419.1 - 0.024 14.3 7.4 0.13 12.0 0.6 2.7 2 0 0 2 2 2 0 Zinc knuckle CPSF100_C PF13299.6 KFM60419.1 - 0.025 14.8 0.6 0.025 14.8 0.6 1.9 2 1 1 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DUF1509 PF07420.11 KFM60419.1 - 0.11 11.4 0.2 0.18 10.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) zf-CCHC_3 PF13917.6 KFM60419.1 - 3.7 7.6 24.6 1.2 9.2 3.1 2.9 1 1 1 2 2 2 0 Zinc knuckle HTH_Tnp_Tc3_2 PF01498.18 KFM60420.1 - 1.9e-16 60.1 2.2 4.4e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60420.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM60421.1 - 2.7e-10 40.3 0.1 1e-09 38.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM60421.1 - 0.00095 18.7 1.4 0.0024 17.4 1.1 1.8 1 1 0 1 1 1 1 Zinc-finger C2H2-type PepX_C PF08530.10 KFM60421.1 - 0.21 11.5 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain CRAL_TRIO PF00650.20 KFM60422.1 - 4.6e-31 107.7 0.0 7.1e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM60422.1 - 4.4e-09 37.0 0.3 0.00013 22.5 0.1 2.4 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 KFM60422.1 - 2.2e-06 27.7 0.2 6.4e-06 26.3 0.2 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM60422.1 - 0.0055 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain ESR1_C PF12743.7 KFM60423.1 - 0.047 13.5 1.0 0.063 13.1 1.0 1.2 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal DDE_3 PF13358.6 KFM60425.1 - 4.7e-16 58.9 0.1 6.6e-15 55.1 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60425.1 - 8.2e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM60425.1 - 0.00078 20.0 1.5 0.00078 20.0 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM60425.1 - 0.0018 18.0 1.0 0.12 12.2 0.0 3.8 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60425.1 - 0.012 15.7 0.1 0.069 13.3 0.1 2.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM60425.1 - 0.038 14.0 0.4 0.038 14.0 0.4 2.7 3 0 0 3 3 3 0 Winged helix-turn helix HTH_7 PF02796.15 KFM60425.1 - 0.13 12.4 0.1 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Anoct_dimer PF16178.5 KFM60426.1 - 8.9e-16 58.3 0.0 9.1e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin HTH_Tnp_Tc3_2 PF01498.18 KFM60428.1 - 4.3e-16 58.9 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60428.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60428.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60428.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60428.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Homeodomain PF00046.29 KFM60429.1 - 4.4e-09 36.0 0.9 7.1e-09 35.4 0.9 1.3 1 0 0 1 1 1 1 Homeodomain zf-C4 PF00105.18 KFM60432.1 - 2.7e-31 107.9 15.1 5.5e-31 106.8 15.1 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFM60432.1 - 2.6e-23 82.7 0.0 5.5e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF1736 PF08409.11 KFM60434.1 - 6.5e-31 106.1 0.9 6.5e-31 106.1 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) MgtE PF01769.16 KFM60434.1 - 0.38 11.1 10.7 1.2 9.6 10.7 1.8 1 1 0 1 1 1 0 Divalent cation transporter Lig_chan PF00060.26 KFM60434.1 - 8.6 6.2 8.5 0.32 10.8 1.3 2.1 2 1 0 2 2 2 0 Ligand-gated ion channel TPR_17 PF13431.6 KFM60435.1 - 1.1e-31 106.9 9.6 6.9e-09 35.5 0.1 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFM60435.1 - 8.8e-27 91.8 9.1 1.5e-05 24.6 0.0 6.3 6 1 0 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFM60435.1 - 2.3e-26 91.2 8.2 9.3e-06 25.2 0.0 6.0 2 2 4 6 6 6 5 TPR repeat TPR_8 PF13181.6 KFM60435.1 - 9.9e-26 87.8 3.6 1.7e-05 24.6 0.0 6.2 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFM60435.1 - 6.1e-25 85.3 10.3 3.4e-05 23.6 0.1 6.2 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFM60435.1 - 7.4e-22 77.4 14.4 5.6e-09 36.2 1.7 4.1 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM60435.1 - 2e-20 73.0 20.3 1.1e-08 35.4 0.3 4.8 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KFM60435.1 - 6.4e-20 69.7 7.5 0.00026 20.8 0.1 6.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFM60435.1 - 7.9e-20 71.2 10.3 1.1e-07 32.4 0.6 4.3 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFM60435.1 - 1.9e-17 62.5 5.2 0.0016 19.1 0.0 5.4 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFM60435.1 - 9.5e-17 60.3 22.2 0.00029 20.6 0.2 6.5 6 1 0 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM60435.1 - 8.4e-11 41.9 1.9 2e-05 24.7 0.2 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFM60435.1 - 3.5e-10 39.9 1.3 0.00054 20.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFM60435.1 - 2.8e-09 36.7 0.0 0.091 13.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM60435.1 - 1.2e-08 35.0 3.3 0.065 13.9 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFM60435.1 - 1.6e-07 30.9 4.9 8.1e-05 22.0 1.3 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 KFM60435.1 - 4e-07 30.6 3.7 2.7e-05 24.6 3.6 2.2 1 1 0 1 1 1 1 Bacterial transcriptional activator domain TPR_MalT PF17874.1 KFM60435.1 - 2.5e-05 23.8 9.2 0.00027 20.4 3.6 3.2 1 1 1 2 2 2 1 MalT-like TPR region Coatomer_E PF04733.14 KFM60435.1 - 0.00018 21.0 2.3 0.037 13.4 0.1 2.7 1 1 2 3 3 3 2 Coatomer epsilon subunit NARP1 PF12569.8 KFM60435.1 - 0.00038 19.5 1.1 0.0017 17.4 0.5 2.0 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 EST1_DNA_bind PF10373.9 KFM60435.1 - 0.00096 18.7 2.1 0.0011 18.5 0.3 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain PPR PF01535.20 KFM60435.1 - 0.0013 18.8 0.0 3.3 8.2 0.0 3.7 3 0 0 3 3 3 1 PPR repeat FAT PF02259.23 KFM60435.1 - 0.0023 17.2 2.3 0.5 9.5 0.1 2.6 1 1 2 3 3 3 2 FAT domain TPR_20 PF14561.6 KFM60435.1 - 0.0034 17.7 3.3 1.4 9.3 0.2 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KFM60435.1 - 0.0075 16.2 4.3 0.075 12.9 0.3 3.0 1 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal TPR_21 PF09976.9 KFM60435.1 - 0.013 15.3 4.2 0.031 14.0 3.4 1.9 1 1 0 2 2 2 0 Tetratricopeptide repeat-like domain MIT PF04212.18 KFM60435.1 - 0.02 14.9 1.1 32 4.7 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_5 PF12688.7 KFM60435.1 - 0.04 14.2 6.4 1.6 9.0 0.4 3.2 1 1 2 3 3 3 0 Tetratrico peptide repeat Mad3_BUB1_I PF08311.12 KFM60435.1 - 0.26 11.3 1.6 28 4.7 0.1 3.7 3 1 1 4 4 4 0 Mad3/BUB1 homology region 1 FUSC PF04632.12 KFM60435.1 - 0.32 9.5 2.4 0.45 9.0 2.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LIM PF00412.22 KFM60437.1 - 1.6e-57 191.6 66.4 8.9e-15 54.7 4.2 5.1 5 0 0 5 5 5 5 LIM domain zf-RRN7 PF11781.8 KFM60437.1 - 0.016 14.9 0.6 0.016 14.9 0.6 7.7 10 0 0 10 10 10 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TAF6_C PF07571.13 KFM60438.1 - 1.9e-30 105.0 0.0 4.7e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Spo0A_C PF08769.11 KFM60438.1 - 0.014 15.5 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal TAF PF02969.17 KFM60439.1 - 1.7e-25 89.0 0.4 2.8e-25 88.3 0.4 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 KFM60439.1 - 0.011 15.8 0.1 0.018 15.1 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KFM60439.1 - 0.032 14.5 0.3 0.067 13.5 0.2 1.6 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KFM60439.1 - 0.036 14.1 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Methyltr_RsmB-F PF01189.17 KFM60440.1 - 1.2e-07 31.5 0.0 1.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF3023 PF11224.8 KFM60440.1 - 0.036 13.9 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) WD40 PF00400.32 KFM60442.1 - 1.3e-19 70.1 0.8 0.0015 19.3 0.0 7.2 6 1 0 6 6 6 5 WD domain, G-beta repeat Lactonase PF10282.9 KFM60442.1 - 0.21 10.8 0.1 0.87 8.8 0.0 1.9 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF3493 PF11998.8 KFM60443.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 SID-1_RNA_chan PF13965.6 KFM60445.1 - 1.1e-66 225.5 1.3 1.5e-66 225.2 1.3 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 WBP-1 PF11669.8 KFM60445.1 - 0.054 14.1 0.2 0.26 11.9 0.1 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 SID-1_RNA_chan PF13965.6 KFM60446.1 - 1.3e-113 380.5 25.8 1.5e-113 380.4 25.8 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 EIID-AGA PF03613.14 KFM60446.1 - 0.66 9.1 12.3 0.23 10.6 1.7 2.4 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component DUF1616 PF07760.11 KFM60446.1 - 3.6 6.9 7.0 11 5.3 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1616) zf-H2C2_2 PF13465.6 KFM60447.1 - 6.4e-100 323.5 77.0 2e-09 37.4 0.3 14.2 14 0 0 14 14 14 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60447.1 - 2.1e-67 220.0 122.1 2.2e-06 27.8 1.0 14.1 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60447.1 - 4.5e-51 167.1 109.8 4.6e-05 23.9 1.0 14.1 14 0 0 14 14 14 14 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM60447.1 - 5e-30 102.9 92.8 0.00025 20.9 0.6 14.4 14 0 0 14 14 14 12 C2H2-type zinc finger zf-met PF12874.7 KFM60447.1 - 6.8e-29 99.4 102.6 0.00012 22.3 0.9 14.5 14 0 0 14 14 14 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60447.1 - 4e-21 74.8 88.5 8.5e-05 22.7 1.0 14.2 11 3 3 14 14 14 9 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM60447.1 - 4.6e-11 42.3 76.1 0.078 12.7 0.2 13.3 13 0 0 13 13 13 8 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM60447.1 - 9.1e-09 35.2 43.2 0.0034 17.3 1.0 9.6 6 3 3 9 9 9 4 Adenylate kinase, active site lid BolA PF01722.18 KFM60447.1 - 7.6e-07 29.3 20.2 1.5 9.1 0.1 9.0 1 1 6 7 7 7 1 BolA-like protein zf-C2HC_2 PF13913.6 KFM60447.1 - 2.7e-06 27.1 45.2 0.28 11.1 0.1 12.5 13 0 0 13 13 13 2 zinc-finger of a C2HC-type GAGA PF09237.11 KFM60447.1 - 1.1e-05 25.1 48.5 0.0036 17.1 1.3 10.2 1 1 12 13 13 13 4 GAGA factor C1_1 PF00130.22 KFM60447.1 - 0.00023 21.0 74.8 2.6 8.0 0.2 12.6 3 2 11 14 14 14 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFM60447.1 - 0.0017 19.0 54.7 1.2 9.9 0.9 7.4 3 1 3 7 7 7 5 zinc-ribbon family zf-MYST PF17772.1 KFM60447.1 - 0.0038 16.8 68.8 1.1 8.9 0.3 13.4 7 3 7 14 14 14 5 MYST family zinc finger domain zf_C2H2_ZHX PF18387.1 KFM60447.1 - 0.019 14.6 1.5 0.019 14.6 1.5 9.5 3 3 6 10 10 10 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-RRPl_C4 PF17026.5 KFM60447.1 - 0.02 15.0 53.1 0.086 12.9 3.9 6.0 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type T4_deiodinase PF00837.17 KFM60447.1 - 0.024 14.0 4.4 1.3 8.2 0.5 3.4 2 2 1 3 3 3 0 Iodothyronine deiodinase Mga PF05043.13 KFM60447.1 - 0.048 14.3 6.1 92 3.7 0.0 5.6 4 1 2 6 6 6 0 Mga helix-turn-helix domain zf_UBZ PF18439.1 KFM60447.1 - 0.076 12.6 59.0 2.5 7.8 0.0 13.0 14 0 0 14 14 14 0 Ubiquitin-Binding Zinc Finger ATP-grasp_4 PF13535.6 KFM60447.1 - 0.11 12.0 0.1 3 7.4 0.0 3.2 2 2 0 3 3 3 0 ATP-grasp domain Zn-ribbon_8 PF09723.10 KFM60447.1 - 1.4 9.1 45.7 2.8 8.1 1.2 8.7 4 3 5 9 9 9 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KFM60447.1 - 1.5 9.2 97.6 1.9 8.8 1.3 13.1 1 1 11 12 12 12 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFM60447.1 - 5.7 7.6 52.8 3.9 8.2 1.6 9.7 5 3 3 9 9 9 0 Zinc finger C2H2-type, 3 repeats M-factor PF03855.13 KFM60447.1 - 8 6.7 5.9 36 4.6 0.1 4.0 4 0 0 4 4 4 0 M-factor WH1 PF00568.23 KFM60448.1 - 6.5e-31 106.6 0.0 7.5e-31 106.4 0.0 1.0 1 0 0 1 1 1 1 WH1 domain DDE_3 PF13358.6 KFM60449.1 - 1e-07 31.8 0.2 1.9e-05 24.5 0.1 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60449.1 - 6.8e-06 26.2 0.6 2.2e-05 24.6 0.6 1.9 1 1 0 1 1 1 1 Transposase Ca_chan_IQ PF08763.11 KFM60449.1 - 0.0045 17.2 0.1 0.0097 16.1 0.1 1.6 1 1 0 1 1 1 1 Voltage gated calcium channel IQ domain Helicase_RecD PF05127.14 KFM60449.1 - 0.066 13.1 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Helicase HTH_32 PF13565.6 KFM60449.1 - 0.097 13.3 0.9 0.097 13.3 0.9 2.4 2 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM60451.1 - 4.2e-16 58.9 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60451.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60451.1 - 1.9e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60451.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60451.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain PALP PF00291.25 KFM60452.1 - 5.6e-53 180.3 0.0 6.8e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KFM60452.1 - 1.6e-18 66.9 0.7 1.5e-10 41.4 0.0 2.8 2 0 0 2 2 2 2 CBS domain BTB PF00651.31 KFM60453.1 - 6.2e-13 48.9 0.0 4.3e-12 46.3 0.0 2.3 1 1 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM60453.1 - 3.4e-11 43.1 1.1 2.1e-10 40.6 0.9 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch RWD PF05773.22 KFM60454.1 - 6.4e-13 49.0 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.12 KFM60454.1 - 1.1e-10 41.8 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) ATP_bind_3 PF01171.20 KFM60455.1 - 3.8e-17 62.6 0.0 5.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KFM60455.1 - 4.2e-13 48.5 2.6 4.2e-13 48.5 2.6 3.4 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 KFM60455.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase zf-RING_UBOX PF13445.6 KFM60455.1 - 0.023 14.7 7.0 0.024 14.7 1.3 3.3 4 0 0 4 4 4 0 RING-type zinc-finger TF_Zn_Ribbon PF08271.12 KFM60455.1 - 0.024 14.1 1.5 0.024 14.1 1.5 3.5 3 0 0 3 3 3 0 TFIIB zinc-binding ThiI PF02568.14 KFM60455.1 - 0.029 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) zf-C3HC4_3 PF13920.6 KFM60455.1 - 0.058 13.3 1.0 0.058 13.3 1.0 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Asp-B-Hydro_N PF05279.11 KFM60456.1 - 2.4 8.2 19.4 3.2 7.8 19.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Trypsin PF00089.26 KFM60457.1 - 1.5e-35 123.0 0.0 1.7e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM60457.1 - 7.7e-07 30.1 0.0 9.4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM60457.1 - 0.00016 22.0 0.0 0.00053 20.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) DUF4951 PF16309.5 KFM60457.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) Mucin PF01456.17 KFM60458.1 - 0.017 15.1 2.4 0.023 14.7 2.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Trypsin PF00089.26 KFM60458.1 - 0.039 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Trypsin Mucin15 PF15672.5 KFM60458.1 - 0.2 11.1 2.5 0.24 10.8 2.5 1.1 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Trypsin PF00089.26 KFM60459.1 - 5.6e-33 114.6 0.1 6.1e-33 114.5 0.1 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_C3 PF00548.20 KFM60459.1 - 0.039 13.9 1.1 0.052 13.5 1.1 1.2 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) HTH_Tnp_Tc3_2 PF01498.18 KFM60461.1 - 3.7e-16 59.1 3.3 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60461.1 - 1.1e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60464.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60464.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60464.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60464.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60464.1 - 1.7 9.3 15.6 0.11 13.1 1.9 3.3 2 1 1 3 3 3 0 Homeodomain-like domain Pkinase PF00069.25 KFM60465.1 - 3.4e-71 239.7 0.0 1.3e-70 237.8 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain cNMP_binding PF00027.29 KFM60465.1 - 1.2e-38 131.0 0.2 2.3e-18 66.0 0.0 3.1 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KFM60465.1 - 4.1e-37 127.9 0.0 1.4e-36 126.1 0.0 1.8 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM60465.1 - 0.0033 16.8 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFM60465.1 - 0.027 14.4 0.0 0.083 12.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFM60465.1 - 0.044 12.8 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4427 PF14468.6 KFM60465.1 - 0.081 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) DUF2228 PF10228.9 KFM60466.1 - 2e-89 299.7 0.1 2e-89 299.7 0.1 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2228) zf-CCHH PF10283.9 KFM60466.1 - 1.5e-08 34.4 5.5 1.5e-08 34.4 5.5 1.8 2 0 0 2 2 2 1 PBZ domain HTH_Tnp_Tc3_2 PF01498.18 KFM60467.1 - 4.6e-16 58.8 3.5 6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60467.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60467.1 - 2.1e-07 30.6 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60467.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60467.1 - 1.8 9.3 19.1 0.13 12.9 2.0 3.9 3 1 1 4 4 4 0 Homeodomain-like domain Homeodomain PF00046.29 KFM60468.1 - 3.4e-14 52.4 1.0 5.1e-14 51.9 1.0 1.2 1 0 0 1 1 1 1 Homeodomain Ribosomal_L1 PF00687.21 KFM60471.1 - 1.2e-14 54.5 0.0 2.7e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family DDE_3 PF13358.6 KFM60472.1 - 3.4e-14 52.8 0.0 4.2e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M13 PF01431.21 KFM60473.1 - 2.2e-44 151.5 0.7 2.4e-44 151.4 0.7 1.0 1 0 0 1 1 1 1 Peptidase family M13 Amidohydro_1 PF01979.20 KFM60474.1 - 2.7e-71 240.7 1.6 1.3e-70 238.4 1.3 1.9 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 KFM60474.1 - 7.6e-52 174.7 3.9 7.6e-52 174.7 3.9 2.0 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KFM60474.1 - 2.8e-36 123.4 0.0 5.1e-36 122.6 0.0 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KFM60474.1 - 4.1e-19 68.7 0.0 9.7e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KFM60474.1 - 1.9e-11 44.1 0.1 5.4e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family HTH_Tnp_Tc3_2 PF01498.18 KFM60475.1 - 3.9e-16 59.1 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60475.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60475.1 - 1.9e-07 30.8 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60475.1 - 0.0023 17.7 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60475.1 - 1.9 9.2 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain zf-CCHC PF00098.23 KFM60476.1 - 0.011 15.8 5.9 0.011 15.8 5.9 2.9 3 0 0 3 3 3 0 Zinc knuckle FlaG PF03646.15 KFM60476.1 - 0.067 13.4 0.2 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 FlaG protein TRM PF02005.16 KFM60476.1 - 0.59 9.2 7.9 0.077 12.1 3.8 1.5 1 1 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase zf-CCHC_5 PF14787.6 KFM60476.1 - 0.93 9.3 14.7 0.071 12.8 5.9 2.5 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KFM60476.1 - 8.9 6.4 19.7 3.3 7.7 11.4 2.7 1 1 1 2 2 2 0 Zinc knuckle Exo_endo_phos_2 PF14529.6 KFM60477.1 - 5.5e-23 81.1 0.7 6.1e-23 80.9 0.7 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM60477.1 - 0.0027 17.3 0.1 0.0038 16.8 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AA_permease PF00324.21 KFM60478.1 - 2.1e-92 310.2 18.0 2.7e-92 309.9 18.0 1.0 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFM60478.1 - 3.6e-38 131.7 0.1 4.4e-38 131.4 0.1 1.1 1 0 0 1 1 1 1 Solute carrier family 12 Peptidase_U57 PF05582.12 KFM60478.1 - 0.097 11.9 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 YabG peptidase U57 AA_permease PF00324.21 KFM60479.1 - 3.4e-22 78.7 12.2 3.6e-22 78.6 12.2 1.0 1 0 0 1 1 1 1 Amino acid permease Caps_synth PF05704.12 KFM60480.1 - 0.021 14.2 1.5 0.03 13.7 1.5 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF5095 PF17016.5 KFM60480.1 - 0.1 12.3 3.8 3.8 7.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5095) adh_short PF00106.25 KFM60481.1 - 1.6e-47 161.5 0.0 2.1e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM60481.1 - 5.4e-31 108.0 0.0 6.7e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM60481.1 - 7.6e-09 35.7 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFM60481.1 - 0.019 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Tmemb_40 PF10160.9 KFM60481.1 - 0.065 12.7 0.0 0.065 12.7 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein DUF2670 PF10875.8 KFM60481.1 - 0.12 12.5 0.9 0.26 11.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) AAA PF00004.29 KFM60482.1 - 2.3e-43 147.8 0.0 6.5e-43 146.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM60482.1 - 1.8e-12 46.8 0.0 4.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFM60482.1 - 5.1e-08 32.7 0.5 1.4e-07 31.4 0.5 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KFM60482.1 - 4.3e-07 30.2 0.7 1.2e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFM60482.1 - 1.2e-06 28.6 0.0 5.1e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM60482.1 - 3.7e-06 27.4 0.3 8.5e-05 23.0 0.0 2.7 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.6 KFM60482.1 - 7.3e-05 23.1 2.2 0.0057 16.9 0.4 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KFM60482.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFM60482.1 - 0.0014 17.9 0.0 0.0037 16.5 0.0 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KFM60482.1 - 0.0018 18.4 0.0 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFM60482.1 - 0.0024 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFM60482.1 - 0.0029 18.2 0.3 0.019 15.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KFM60482.1 - 0.0064 15.9 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFM60482.1 - 0.0064 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KFM60482.1 - 0.0094 15.3 1.5 0.04 13.2 0.0 2.4 2 0 0 2 2 2 1 KaiC PhoH PF02562.16 KFM60482.1 - 0.012 15.1 0.1 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KFM60482.1 - 0.017 14.9 0.1 0.1 12.3 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFM60482.1 - 0.018 15.3 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFM60482.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KFM60482.1 - 0.025 14.3 0.0 0.12 12.1 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain TsaE PF02367.17 KFM60482.1 - 0.038 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KFM60482.1 - 0.047 12.8 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KFM60482.1 - 0.048 13.2 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 KFM60482.1 - 0.056 13.9 0.9 0.36 11.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.6 KFM60482.1 - 0.057 13.2 1.0 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFM60482.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.7 KFM60482.1 - 0.061 12.9 6.8 0.1 12.1 6.8 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF815 PF05673.13 KFM60482.1 - 0.062 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KFM60482.1 - 0.084 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SlyX PF04102.12 KFM60482.1 - 0.084 13.5 2.4 0.33 11.6 2.4 2.0 1 0 0 1 1 1 0 SlyX AAA_19 PF13245.6 KFM60482.1 - 0.12 12.7 0.1 0.48 10.8 0.1 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM60482.1 - 0.14 12.7 0.5 1.2 9.7 0.0 2.5 3 0 0 3 3 2 0 ABC transporter RILP PF11461.8 KFM60482.1 - 0.14 12.4 6.4 0.26 11.6 5.8 1.7 1 1 0 1 1 1 0 Rab interacting lysosomal protein APG6_N PF17675.1 KFM60482.1 - 0.45 11.0 5.6 1.1 9.8 5.6 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region EAF PF09816.9 KFM60483.1 - 5.2e-21 74.9 0.0 1.3e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor FtsK_SpoIIIE_N PF12538.8 KFM60483.1 - 0.12 12.6 0.2 2.4 8.4 0.0 2.3 1 1 0 2 2 2 0 DNA transporter PA28_beta PF02252.18 KFM60484.1 - 5.7e-64 214.2 0.2 1e-63 213.4 0.2 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KFM60484.1 - 6e-25 87.1 0.6 1.4e-24 85.9 0.6 1.7 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit DUF1577 PF07614.11 KFM60484.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) C2 PF00168.30 KFM60485.1 - 6.6e-19 68.1 0.1 1.7e-10 41.1 0.0 2.6 2 1 0 2 2 2 2 C2 domain DOCK-C2 PF14429.6 KFM60485.1 - 0.082 12.7 0.2 0.33 10.7 0.1 2.0 1 1 1 2 2 2 0 C2 domain in Dock180 and Zizimin proteins zf-Tim10_DDP PF02953.15 KFM60486.1 - 2e-12 46.6 4.3 2.2e-12 46.4 4.3 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cofilin_ADF PF00241.20 KFM60488.1 - 2.9e-28 98.1 0.4 3.7e-24 84.8 0.2 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein CAP PF00188.26 KFM60491.1 - 3.4e-09 37.6 1.2 4.5e-09 37.2 1.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KFM60493.1 - 3.9e-22 79.4 0.6 6.8e-22 78.6 0.6 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KFM60495.1 - 2.8e-20 73.4 1.2 4.1e-20 72.9 1.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family LSR PF05624.14 KFM60495.1 - 2 8.5 10.1 0.97 9.5 0.1 2.5 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) WD40 PF00400.32 KFM60497.1 - 2.1e-24 85.3 23.0 0.0004 21.1 0.1 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM60497.1 - 4.2e-10 39.8 9.4 0.00055 20.2 0.1 4.4 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 KFM60498.1 - 9e-61 205.5 0.0 1e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM60498.1 - 1.4e-28 99.9 0.0 1.8e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM60498.1 - 1e-07 31.6 0.0 1.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFM60498.1 - 0.04 13.9 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM60498.1 - 0.043 12.6 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase START PF01852.19 KFM60499.1 - 9e-32 110.2 0.1 1e-31 110.0 0.1 1.0 1 0 0 1 1 1 1 START domain SAD_SRA PF02182.17 KFM60499.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 1 0 1 1 1 0 SAD/SRA domain WD40 PF00400.32 KFM60500.1 - 4.6e-47 157.0 15.6 1.7e-06 28.6 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat SAM_2 PF07647.17 KFM60500.1 - 2.1e-14 53.3 0.9 2.1e-14 53.3 0.9 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM60500.1 - 3.2e-14 53.1 1.4 5.2e-14 52.4 0.5 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) ANAPC4_WD40 PF12894.7 KFM60500.1 - 5.2e-13 49.1 0.0 0.011 16.0 0.0 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 KFM60500.1 - 2.4e-11 43.6 0.0 4.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 U-box domain Ge1_WD40 PF16529.5 KFM60500.1 - 8.2e-06 25.0 4.7 1.6 7.6 0.0 5.1 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein SAM_PNT PF02198.16 KFM60500.1 - 0.00069 19.5 0.2 0.0031 17.5 0.1 2.1 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Frtz PF11768.8 KFM60500.1 - 0.0047 15.3 0.0 0.0098 14.3 0.0 1.4 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz zf-NOSIP PF15906.5 KFM60500.1 - 0.008 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KFM60500.1 - 0.008 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Homeodomain PF00046.29 KFM60502.1 - 1.2e-21 76.3 7.6 2e-21 75.5 7.6 1.4 1 0 0 1 1 1 1 Homeodomain Engrail_1_C_sig PF10525.9 KFM60502.1 - 1.7e-15 55.9 0.0 3.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain Homeobox_KN PF05920.11 KFM60502.1 - 0.082 12.8 0.8 0.21 11.5 0.9 1.7 2 0 0 2 2 2 0 Homeobox KN domain DUF2316 PF10078.9 KFM60502.1 - 0.098 12.9 0.3 0.15 12.3 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Myosin_tail_1 PF01576.19 KFM60503.1 - 5.1e-20 71.0 137.9 5e-15 54.5 76.4 3.2 1 1 2 3 3 3 2 Myosin tail Cortex-I_coil PF09304.10 KFM60503.1 - 0.0044 17.2 5.4 0.0044 17.2 5.4 7.8 1 1 7 9 9 9 2 Cortexillin I, coiled coil VP4_helical PF17478.2 KFM60503.1 - 0.31 10.5 5.8 13 5.1 0.1 3.3 3 0 0 3 3 3 0 Rotavirus VP4 helical domain p450 PF00067.22 KFM60504.1 - 9.9e-12 44.3 0.0 1.1e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM60505.1 - 4e-29 101.7 0.1 4.3e-29 101.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nipped-B_C PF12830.7 KFM60505.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus p450 PF00067.22 KFM60506.1 - 2.3e-28 99.2 1.0 2.5e-28 99.1 1.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 S4 PF01479.25 KFM60506.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 S4 domain Lipocalin PF00061.23 KFM60507.1 - 1.2e-19 71.0 2.0 1.3e-19 70.8 2.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFM60507.1 - 3.7e-10 39.8 3.1 4.2e-10 39.6 3.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Myosin_N PF02736.19 KFM60507.1 - 4.7 7.1 8.1 8.4 6.3 1.3 3.2 2 1 2 4 4 4 0 Myosin N-terminal SH3-like domain zf-H2C2_2 PF13465.6 KFM60508.1 - 3.2e-56 185.4 53.1 7.3e-08 32.5 0.3 9.6 10 0 0 10 10 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60508.1 - 2.8e-42 140.9 72.4 6.9e-06 26.2 0.2 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60508.1 - 4e-29 98.8 67.2 0.00041 21.0 0.3 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM60508.1 - 6e-24 83.5 63.7 4.9e-05 23.2 0.3 9.7 10 0 0 10 10 9 7 C2H2-type zinc finger zf-met PF12874.7 KFM60508.1 - 8.3e-23 80.0 64.6 0.00018 21.8 0.9 9.2 9 0 0 9 9 9 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60508.1 - 1e-17 63.9 49.6 0.0095 16.2 0.1 9.3 9 0 0 9 9 9 7 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM60508.1 - 3.2e-06 26.9 37.2 0.61 10.1 0.3 9.1 9 0 0 9 9 9 3 zinc-finger of a C2HC-type DZR PF12773.7 KFM60508.1 - 0.0002 21.3 23.3 3 8.0 6.7 5.1 1 1 1 2 2 1 1 Double zinc ribbon DUF2256 PF10013.9 KFM60508.1 - 0.00047 20.2 27.2 12 6.1 0.1 9.0 8 1 2 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_ZIC PF18366.1 KFM60508.1 - 0.00056 20.0 45.4 2.1 8.5 0.2 9.1 3 3 6 9 9 9 1 Zic proteins zinc finger domain BolA PF01722.18 KFM60508.1 - 0.00092 19.4 14.4 6.7 7.1 0.2 6.2 2 2 3 5 5 5 0 BolA-like protein Prok-RING_1 PF14446.6 KFM60508.1 - 0.0017 18.2 27.6 16 5.5 0.1 8.7 8 1 1 9 9 9 0 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 KFM60508.1 - 0.0017 17.9 32.9 5.1 6.8 0.9 8.3 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM60508.1 - 0.0061 16.1 42.4 0.04 13.5 0.2 8.4 2 2 7 9 9 9 1 MYST family zinc finger domain GAGA PF09237.11 KFM60508.1 - 0.0084 15.9 0.2 0.0084 15.9 0.2 4.6 3 3 4 7 7 6 1 GAGA factor LIM PF00412.22 KFM60508.1 - 0.01 16.0 40.7 1.5 9.1 2.4 6.8 2 2 2 6 6 6 0 LIM domain CTV_P23 PF04808.12 KFM60508.1 - 0.018 14.6 2.8 0.88 9.1 0.2 2.3 2 1 1 3 3 3 0 Citrus tristeza virus (CTV) P23 protein ADK_lid PF05191.14 KFM60508.1 - 0.023 14.6 36.5 0.12 12.4 1.0 6.2 4 2 1 5 5 5 0 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 KFM60508.1 - 0.074 12.8 0.3 0.074 12.8 0.3 6.8 8 0 0 8 8 6 0 zinc-finger C2H2-type HNH_5 PF14279.6 KFM60508.1 - 0.082 12.8 32.0 1.8 8.5 1.8 7.8 6 2 1 7 7 7 0 HNH endonuclease zf-C2H2_2 PF12756.7 KFM60508.1 - 0.088 13.1 49.9 1.9 8.8 11.5 7.0 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) OSTMP1 PF09777.9 KFM60508.1 - 0.27 10.6 22.9 2.2 7.6 4.7 2.7 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor zinc_ribbon_15 PF17032.5 KFM60508.1 - 0.77 10.6 33.8 0.76 10.6 6.1 5.1 1 1 3 4 4 4 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM60508.1 - 1 9.5 32.3 1.2 9.3 0.5 6.1 5 1 2 7 7 7 0 Zinc ribbon domain Evr1_Alr PF04777.13 KFM60508.1 - 1.1 9.8 27.3 0.27 11.7 3.4 5.3 1 1 5 6 6 6 0 Erv1 / Alr family DUF899 PF05988.12 KFM60508.1 - 1.4 8.4 9.3 2.8 7.4 1.6 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF899) DNA_RNApol_7kD PF03604.13 KFM60508.1 - 1.5 8.6 0.0 1.5 8.6 0.0 4.2 5 0 0 5 5 4 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_3rep PF18868.1 KFM60508.1 - 1.7 9.4 35.6 20 5.9 0.2 7.5 3 2 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats Zf_RING PF16744.5 KFM60508.1 - 4.4 7.5 39.7 4.4 7.5 0.5 8.1 2 1 7 9 9 9 0 KIAA1045 RING finger zf-Sec23_Sec24 PF04810.15 KFM60508.1 - 6.4 6.9 27.9 0.62 10.2 0.8 7.2 8 1 1 9 9 8 0 Sec23/Sec24 zinc finger zf-FPG_IleRS PF06827.14 KFM60508.1 - 6.6 6.7 22.4 13 5.7 0.0 6.7 7 0 0 7 7 7 0 Zinc finger found in FPG and IleRS zf-RRPl_C4 PF17026.5 KFM60508.1 - 9.4 6.4 35.0 20 5.4 6.1 4.7 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type CH PF00307.31 KFM60511.1 - 2.7e-12 46.8 1.2 2e-11 44.0 0.0 2.8 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM60511.1 - 0.00042 20.1 0.5 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 1 CAMSAP CH domain TPR_MLP1_2 PF07926.12 KFM60511.1 - 0.001 19.1 17.8 0.001 19.1 17.8 6.6 3 2 3 6 6 6 2 TPR/MLP1/MLP2-like protein Filament PF00038.21 KFM60511.1 - 0.0047 16.6 17.0 0.0047 16.6 17.0 5.9 3 1 3 6 6 6 2 Intermediate filament protein ADIP PF11559.8 KFM60511.1 - 0.074 13.1 98.8 0.049 13.7 14.3 6.7 4 1 2 6 6 6 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KFM60511.1 - 0.18 10.6 100.5 0.06 12.2 23.9 4.8 2 1 1 4 4 4 0 Spc7 kinetochore protein YabA PF06156.13 KFM60511.1 - 0.51 11.0 82.6 1.2 9.8 2.0 7.9 4 3 3 7 7 7 0 Initiation control protein YabA GAS PF13851.6 KFM60511.1 - 2.6 7.3 102.5 0.043 13.2 32.9 5.8 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding PP2C PF00481.21 KFM60512.1 - 1.7e-06 27.9 0.1 1.8e-06 27.8 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C HLH PF00010.26 KFM60513.1 - 1.7e-18 66.3 4.4 2.5e-18 65.8 4.4 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mucin-like PF16058.5 KFM60514.1 - 0.047 13.8 5.6 0.11 12.5 5.6 1.6 1 0 0 1 1 1 0 Mucin-like HTH_Tnp_Tc3_2 PF01498.18 KFM60516.1 - 1.4e-15 57.2 2.9 1.9e-15 56.8 1.6 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60516.1 - 1.3e-05 25.0 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_IclR PF09339.10 KFM60516.1 - 0.00034 20.3 0.0 0.001 18.8 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KFM60516.1 - 0.012 15.4 1.1 0.012 15.4 1.1 2.5 2 1 1 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 KFM60516.1 - 0.038 13.7 1.1 0.084 12.7 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 KFM60516.1 - 0.04 13.8 0.5 0.24 11.3 0.2 2.2 2 0 0 2 2 2 0 MarR family HTH_32 PF13565.6 KFM60516.1 - 0.25 12.0 16.8 0.11 13.2 3.5 3.4 2 1 2 4 4 4 0 Homeodomain-like domain HTH_31 PF13560.6 KFM60516.1 - 1.3 9.4 11.5 7.3 7.0 7.0 3.4 2 1 0 2 2 2 0 Helix-turn-helix domain zf-met PF12874.7 KFM60518.1 - 0.016 15.6 1.2 0.016 15.6 1.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM60518.1 - 0.018 15.8 2.9 0.018 15.8 2.9 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger TetR_C_30 PF17939.1 KFM60518.1 - 0.058 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GPR15L PF15854.5 KFM60518.1 - 0.088 13.1 0.6 0.088 13.1 0.6 2.5 3 0 0 3 3 3 0 G-protein coupled receptor ligand 15 zf-Di19 PF05605.12 KFM60518.1 - 1.1 9.6 7.8 0.19 12.1 3.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Syntaxin-6_N PF09177.11 KFM60519.1 - 1.4e-35 121.8 7.4 1.3e-34 118.7 2.5 2.1 2 0 0 2 2 2 2 Syntaxin 6, N-terminal DUF3450 PF11932.8 KFM60519.1 - 0.36 10.1 5.5 0.75 9.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Sec34 PF04136.15 KFM60519.1 - 0.9 9.4 5.9 0.24 11.3 1.1 2.1 2 0 0 2 2 2 0 Sec34-like family FlaC_arch PF05377.11 KFM60519.1 - 1.7 9.1 7.5 17 5.9 0.2 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DHHC PF01529.20 KFM60521.1 - 2e-31 108.9 16.4 2.8e-31 108.4 16.4 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Suppressor_APC PF11414.8 KFM60522.1 - 9.9e-28 96.0 7.5 1.4e-27 95.6 3.0 2.8 2 1 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein POX PF07526.11 KFM60522.1 - 0.015 15.8 0.2 0.044 14.4 0.0 1.8 2 0 0 2 2 2 0 Associated with HOX APG6_N PF17675.1 KFM60522.1 - 0.028 15.0 11.4 0.37 11.3 5.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KFM60522.1 - 0.044 14.0 7.6 0.12 12.6 2.6 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KFM60522.1 - 0.093 12.1 0.8 0.14 11.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMCO5 PF14992.6 KFM60522.1 - 0.18 11.4 9.6 0.45 10.0 9.6 1.6 1 1 0 1 1 1 0 TMCO5 family DivIC PF04977.15 KFM60522.1 - 0.24 11.2 5.2 0.56 10.0 3.6 2.2 2 0 0 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.8 KFM60522.1 - 0.38 11.0 7.2 0.2 11.9 1.5 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KFM60522.1 - 0.49 10.4 5.4 0.37 10.8 2.7 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BRE1 PF08647.11 KFM60522.1 - 1.1 9.4 8.2 0.27 11.3 2.9 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 KFM60522.1 - 1.1 9.3 9.1 0.34 11.0 5.0 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fungal_TACC PF12709.7 KFM60522.1 - 2.7 8.5 7.4 0.56 10.7 1.0 2.8 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins ZapB PF06005.12 KFM60522.1 - 3.5 8.1 8.8 0.38 11.2 3.0 2.4 3 0 0 3 3 3 0 Cell division protein ZapB Prefoldin PF02996.17 KFM60522.1 - 6.2 6.8 8.2 3.5 7.6 3.3 2.7 3 0 0 3 3 3 0 Prefoldin subunit DDE_3 PF13358.6 KFM60524.1 - 4.7e-16 58.9 0.1 5.8e-15 55.3 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60524.1 - 7.7e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM60524.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM60524.1 - 0.00087 19.0 0.1 0.037 13.8 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60524.1 - 0.01 16.0 0.1 0.046 13.9 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM60524.1 - 0.02 14.9 2.5 0.024 14.7 0.3 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM60524.1 - 0.029 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Ribosomal_L17 PF01196.19 KFM60525.1 - 3.2e-11 44.0 0.0 5.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 GFA PF04828.14 KFM60526.1 - 0.023 15.0 0.4 0.29 11.5 0.1 2.3 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Rhodanese PF00581.20 KFM60527.1 - 0.00028 21.4 0.1 0.001 19.6 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain ZapB PF06005.12 KFM60527.1 - 0.03 14.8 1.5 0.091 13.2 1.5 1.8 1 1 0 1 1 1 0 Cell division protein ZapB DDE_Tnp_1_7 PF13843.6 KFM60528.1 - 8.5e-26 91.1 0.1 1.1e-25 90.8 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_3 PF13358.6 KFM60529.1 - 1.5e-10 41.0 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease SANT_DAMP1_like PF16282.5 KFM60531.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DDE_3 PF13358.6 KFM60535.1 - 3.5e-09 36.6 0.1 4.7e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PNP_UDP_1 PF01048.20 KFM60537.1 - 8.7e-46 156.1 0.0 1e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily SIS PF01380.22 KFM60539.1 - 7.3e-65 216.7 0.0 4.8e-35 120.3 0.0 2.2 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KFM60539.1 - 6.3e-16 58.8 0.0 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFM60539.1 - 1.5e-12 47.5 0.0 3.2e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KFM60539.1 - 1.3e-05 24.3 0.1 2.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KFM60539.1 - 0.00055 20.0 0.0 0.0037 17.3 0.0 2.3 2 0 0 2 2 2 1 SIS domain Snapin_Pallidin PF14712.6 KFM60540.1 - 8.3e-17 61.4 8.4 8.3e-17 61.4 8.4 2.0 3 0 0 3 3 3 1 Snapin/Pallidin AAA_13 PF13166.6 KFM60540.1 - 0.0047 15.6 7.5 0.0055 15.4 7.5 1.1 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KFM60540.1 - 3.1 8.2 12.1 4.2 7.8 12.1 1.3 1 0 0 1 1 1 0 AAA domain XK-related PF09815.9 KFM60541.1 - 7.1e-09 35.2 5.3 9e-09 34.8 5.3 1.1 1 0 0 1 1 1 1 XK-related protein DDE_Tnp_1_7 PF13843.6 KFM60542.1 - 2e-11 43.8 0.0 2e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 CS PF04969.16 KFM60543.1 - 1.9e-18 67.2 1.1 1.9e-18 67.2 1.1 1.8 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.6 KFM60543.1 - 1.6e-11 44.0 0.0 4.1e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. NuDC PF16273.5 KFM60543.1 - 3.3e-06 27.5 23.9 3.3e-06 27.5 23.9 3.0 2 2 1 3 3 3 1 Nuclear distribution C domain MetOD1 PF18546.1 KFM60543.1 - 0.13 12.2 5.3 9.2 6.2 0.1 3.4 3 1 0 3 3 3 0 Metanogen output domain 1 FHIPEP PF00771.20 KFM60543.1 - 0.2 10.1 1.2 0.32 9.4 1.2 1.3 1 0 0 1 1 1 0 FHIPEP family Presenilin PF01080.17 KFM60543.1 - 1.1 8.0 9.5 1.7 7.4 9.5 1.2 1 0 0 1 1 1 0 Presenilin Membralin PF09746.9 KFM60543.1 - 2.2 7.2 5.9 3.8 6.4 5.9 1.4 1 0 0 1 1 1 0 Tumour-associated protein DUF4769 PF15992.5 KFM60544.1 - 0.068 13.0 4.4 5.1 6.8 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4769) DcpS_C PF11969.8 KFM60545.1 - 4 7.9 7.3 6.1 7.4 2.8 2.0 1 1 1 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding Phosducin PF02114.16 KFM60546.1 - 6.2e-64 215.5 5.8 5.7e-63 212.3 5.8 2.0 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KFM60546.1 - 0.00015 21.7 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin PIN_8 PF18476.1 KFM60546.1 - 0.0036 17.2 3.0 0.0057 16.5 3.0 1.3 1 0 0 1 1 1 1 PIN like domain Complex1_LYR_2 PF13233.6 KFM60546.1 - 4.1 8.2 6.9 29 5.5 6.4 2.1 1 1 1 2 2 2 0 Complex1_LYR-like Pkinase PF00069.25 KFM60547.1 - 4.7e-07 29.4 0.2 4.9e-07 29.4 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM60547.1 - 0.012 14.9 0.1 0.013 14.8 0.1 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KFM60548.1 - 2.1e-14 53.5 0.1 2.1e-14 53.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM60548.1 - 5.4e-06 25.9 0.0 5.4e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KFM60548.1 - 0.0051 15.9 0.1 0.0053 15.9 0.1 1.0 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KFM60548.1 - 0.027 14.4 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM60548.1 - 0.049 12.4 0.1 0.053 12.3 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 KFM60549.1 - 1.7e-46 156.7 6.9 3.8e-17 62.6 0.0 5.6 1 1 6 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM60549.1 - 1.4e-36 124.1 10.8 1.9e-09 37.6 0.0 10.1 2 1 9 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM60549.1 - 3.9e-32 106.7 10.2 0.0004 20.6 0.1 11.2 11 0 0 11 11 11 7 Ankyrin repeat Ank_4 PF13637.6 KFM60549.1 - 1e-30 105.7 9.6 1.8e-13 50.7 0.1 7.8 2 1 8 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 KFM60549.1 - 7.3e-29 98.9 14.8 0.00078 19.8 0.0 10.5 10 0 0 10 10 10 7 Ankyrin repeat TPR_2 PF07719.17 KFM60549.1 - 4.6e-06 26.3 4.9 0.0031 17.5 0.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM60549.1 - 3.8e-05 23.3 4.4 0.016 15.0 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM60549.1 - 4.6e-05 23.5 0.6 9.7e-05 22.4 0.6 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM60549.1 - 9.6e-05 22.3 0.3 0.63 10.4 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM60549.1 - 0.00014 22.4 3.6 0.0043 17.7 0.6 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM60549.1 - 0.032 13.9 0.8 0.12 12.1 0.1 2.2 1 1 1 2 2 2 0 TPR repeat TPR_15 PF13429.6 KFM60549.1 - 0.04 13.1 0.3 0.071 12.3 0.3 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM60549.1 - 0.065 14.1 4.2 0.093 13.6 0.6 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM60549.1 - 2 9.0 5.0 42 4.7 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 KFM60550.1 - 0.00049 20.5 0.1 0.0041 17.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KFM60550.1 - 0.0019 18.5 0.0 0.0038 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM60550.1 - 0.0036 16.6 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.6 KFM60550.1 - 0.0099 15.9 0.0 0.099 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KFM60550.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.9 KFM60550.1 - 0.023 13.9 0.0 0.099 11.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.6 KFM60550.1 - 0.035 14.4 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KFM60550.1 - 0.041 13.4 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ATPase_2 PF01637.18 KFM60550.1 - 0.045 13.7 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KFM60550.1 - 0.046 13.6 0.3 8 6.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.9 KFM60550.1 - 0.063 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KFM60550.1 - 0.072 13.4 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFM60550.1 - 0.12 12.0 0.0 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KFM60550.1 - 0.14 11.2 0.0 0.43 9.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 KFM60550.1 - 0.21 11.3 0.0 0.54 10.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-C3HC4 PF00097.25 KFM60550.1 - 0.23 11.4 15.6 0.071 13.0 11.4 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-primase PF09329.11 KFM60550.1 - 0.55 10.1 4.6 1.4 8.8 4.6 1.6 1 0 0 1 1 1 0 Primase zinc finger zf-RING_2 PF13639.6 KFM60550.1 - 1.2 9.5 15.1 5 7.5 15.1 2.2 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KFM60550.1 - 1.3 9.0 14.2 4.9 7.2 14.2 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM60550.1 - 1.7 8.5 18.9 16 5.4 14.3 3.4 3 1 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM60550.1 - 3.7 7.5 11.9 12 5.9 11.9 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Bunya_G2 PF03563.13 KFM60551.1 - 1.8 7.8 6.2 1.8 7.8 6.2 1.0 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 HTH_Tnp_Tc3_2 PF01498.18 KFM60552.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60552.1 - 1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60553.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60553.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60553.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60553.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60553.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM60554.1 - 2.3e-16 59.8 4.1 6.1e-16 58.4 2.2 2.5 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60554.1 - 1.2e-13 51.1 0.0 2.5e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60554.1 - 9e-07 28.6 0.8 3.7e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60554.1 - 0.012 15.4 0.3 0.035 13.9 0.3 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM60554.1 - 9.9 6.9 14.5 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain PC-Esterase PF13839.6 KFM60556.1 - 0.00064 19.6 0.8 0.0012 18.7 0.9 1.6 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Lipase_GDSL PF00657.22 KFM60556.1 - 0.02 14.9 0.0 0.049 13.6 0.0 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase HTH_Tnp_Tc3_2 PF01498.18 KFM60558.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60558.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2 PF00096.26 KFM60559.1 - 2.8e-18 65.3 34.8 0.00049 20.4 0.4 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM60559.1 - 2.8e-12 46.5 25.6 9.1e-07 29.0 1.2 5.5 5 0 0 5 5 5 3 Zinc-finger double domain FOXP-CC PF16159.5 KFM60559.1 - 0.00028 21.4 33.9 0.017 15.7 2.7 6.9 3 1 2 6 6 6 3 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KFM60559.1 - 0.027 15.3 41.1 0.027 15.3 0.3 6.9 7 0 0 7 7 7 0 C2H2-type zinc finger zf_ZIC PF18366.1 KFM60559.1 - 0.19 11.9 6.6 0.55 10.4 0.3 3.6 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 KFM60559.1 - 1 9.4 8.0 2.7 8.1 2.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFM60559.1 - 1.8 8.6 14.6 2.5 8.2 2.3 3.8 2 1 1 3 3 3 0 Aberrant zinc-finger Ig_3 PF13927.6 KFM60560.1 - 5e-24 84.7 1.6 1.5e-09 38.3 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM60560.1 - 2e-17 63.3 1.2 2.8e-08 34.0 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM60560.1 - 3.5e-14 52.6 0.2 3.1e-10 40.0 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 KFM60560.1 - 9.7e-13 48.1 0.1 0.0018 18.4 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFM60560.1 - 1e-10 41.5 0.3 2.8e-08 33.7 0.1 3.5 3 1 1 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM60560.1 - 0.00016 21.2 0.1 0.77 9.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.11 KFM60560.1 - 0.0023 17.9 0.5 0.026 14.5 0.1 2.6 1 1 1 2 2 2 1 CD47 immunoglobulin-like domain V-set PF07686.17 KFM60560.1 - 0.047 13.9 0.1 0.29 11.3 0.1 2.3 2 1 0 2 2 2 0 Immunoglobulin V-set domain zf-H2C2_2 PF13465.6 KFM60561.1 - 8.1e-104 335.8 135.1 1.1e-08 35.1 2.5 17.4 17 1 0 17 17 17 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60561.1 - 2.5e-78 254.4 150.5 1.8e-06 28.1 2.3 16.1 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60561.1 - 4.8e-58 188.8 142.9 0.00044 20.9 0.8 16.1 16 0 0 16 16 16 16 C2H2-type zinc finger zf-met PF12874.7 KFM60561.1 - 1.4e-44 149.2 134.4 0.00044 20.5 0.7 16.3 16 0 0 16 16 16 15 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60561.1 - 4.3e-17 61.9 119.8 0.017 15.4 2.0 16.6 14 2 2 16 16 16 12 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM60561.1 - 1.5e-12 47.0 91.4 0.017 14.8 0.3 16.2 16 0 0 16 16 16 6 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM60561.1 - 2.6e-12 46.4 125.2 0.002 18.1 1.4 17.6 16 2 0 16 16 16 9 C2H2-type zinc finger ADK_lid PF05191.14 KFM60561.1 - 5.3e-07 29.5 55.2 0.041 13.9 0.3 10.1 3 2 8 11 11 11 6 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KFM60561.1 - 1.3e-06 28.3 64.9 1.7 8.7 0.1 14.5 12 3 3 15 15 15 5 Sec23/Sec24 zinc finger BolA PF01722.18 KFM60561.1 - 4.8e-06 26.8 34.4 0.041 14.2 0.6 9.1 1 1 6 8 8 8 1 BolA-like protein zf-C2HC_2 PF13913.6 KFM60561.1 - 0.00027 20.8 73.9 1.9 8.4 0.1 15.3 16 0 0 16 16 16 3 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM60561.1 - 0.0011 19.0 90.0 4.1 7.6 0.3 15.5 15 1 1 16 16 15 3 DBF zinc finger Tox-HNH-HHH PF15637.6 KFM60561.1 - 0.0051 17.0 14.7 3 8.0 0.3 5.7 3 1 3 7 7 6 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF2256 PF10013.9 KFM60561.1 - 0.073 13.2 61.3 29 4.9 0.1 14.8 15 0 0 15 15 15 0 Uncharacterized protein conserved in bacteria (DUF2256) NAD_kinase PF01513.21 KFM60561.1 - 0.1 11.8 0.9 31 3.6 0.0 3.8 2 1 1 4 4 4 0 ATP-NAD kinase zf-RRPl_C4 PF17026.5 KFM60561.1 - 0.18 11.9 76.6 0.9 9.7 1.7 7.6 1 1 7 8 8 8 0 Putative ribonucleoprotein zinc-finger pf C4 type PqqA PF08042.11 KFM60561.1 - 0.18 11.9 9.4 6.1e+02 0.7 0.0 8.5 11 0 0 11 11 11 0 PqqA family GAGA PF09237.11 KFM60561.1 - 0.28 11.0 41.2 0.52 10.2 0.1 9.5 4 2 9 13 13 13 0 GAGA factor zinc_ribbon_15 PF17032.5 KFM60561.1 - 0.6 10.9 65.7 5.6 7.8 0.7 7.7 5 1 2 7 7 6 0 zinc-ribbon family zf-CHCC PF10276.9 KFM60561.1 - 3.6 7.7 30.5 26 5.0 0.0 11.0 15 0 0 15 15 15 0 Zinc-finger domain zf-MYST PF17772.1 KFM60561.1 - 4.5 7.0 83.7 0.25 11.0 0.3 14.3 8 3 7 15 15 15 0 MYST family zinc finger domain FYVE PF01363.21 KFM60561.1 - 9.2 6.5 92.7 8.9 6.5 8.6 8.9 1 1 6 7 7 6 0 FYVE zinc finger Mtf2_C PF14061.6 KFM60562.1 - 0.0093 16.1 0.1 0.026 14.7 0.1 1.7 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 FOXP-CC PF16159.5 KFM60563.1 - 0.0045 17.6 0.8 0.0045 17.6 0.8 2.5 1 1 1 2 2 2 1 FOXP coiled-coil domain DDE_Tnp_1_7 PF13843.6 KFM60564.1 - 1.2e-58 199.1 0.1 1.6e-58 198.7 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM60564.1 - 0.12 13.3 9.1 0.16 12.8 6.2 2.6 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon SCAN PF02023.17 KFM60565.1 - 2.2e-07 30.6 0.1 3.2e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 SCAN domain Pannexin_like PF12534.8 KFM60566.1 - 1.6 7.8 4.1 2 7.4 4.1 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 adh_short_C2 PF13561.6 KFM60567.1 - 6.9e-27 94.5 0.0 7.8e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM60567.1 - 3.1e-07 30.1 0.1 3.8e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase POB3_N PF17292.2 KFM60569.1 - 6.6e-29 100.2 0.5 4.4e-25 87.9 0.2 2.8 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 KFM60569.1 - 2e-26 91.7 0.1 5.8e-26 90.2 0.0 1.9 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KFM60569.1 - 2e-25 89.0 0.0 2.2e-24 85.7 0.0 2.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like HMG_box PF00505.19 KFM60569.1 - 1.3e-20 73.6 3.8 1.3e-20 73.6 3.8 2.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM60569.1 - 1.5e-12 47.9 4.2 1.5e-12 47.9 4.2 2.2 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.13 KFM60569.1 - 0.0054 17.3 5.1 0.0054 17.3 5.1 2.5 1 1 1 2 2 2 1 YABBY protein Transposase_1 PF01359.18 KFM60570.1 - 2.1e-11 43.5 0.0 2.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Transposase (partial DDE domain) Glycolytic PF00274.19 KFM60571.1 - 1.9e-186 618.9 0.0 2.1e-186 618.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I 5-FTHF_cyc-lig PF01812.20 KFM60572.1 - 1.9e-26 93.1 0.0 8.7e-26 90.9 0.0 1.8 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Acyltransferase PF01553.21 KFM60573.1 - 8.4e-16 57.8 0.0 3.4e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase DAO PF01266.24 KFM60574.1 - 7.6e-43 147.4 0.0 9.3e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Arrestin_N PF00339.29 KFM60575.1 - 1.6e-34 119.1 0.0 2.3e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFM60575.1 - 5.5e-09 36.6 0.0 3.5e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 KFM60575.1 - 0.026 13.7 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Rgp1 FA_hydroxylase PF04116.13 KFM60576.1 - 0.00031 21.1 11.7 0.022 15.1 6.8 3.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Carboxyl_trans PF01039.22 KFM60577.1 - 1.2e-41 143.0 0.0 1.5e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain E1_DerP2_DerF2 PF02221.15 KFM60578.1 - 0.0036 17.7 0.0 0.0041 17.5 0.0 1.1 1 0 0 1 1 1 1 ML domain HTH_Tnp_Tc3_2 PF01498.18 KFM60579.1 - 3.7e-16 59.1 3.5 5.6e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60579.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60579.1 - 1.9e-07 30.8 1.2 7e-07 28.9 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60579.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60579.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Ras PF00071.22 KFM60580.1 - 5.1e-11 42.4 0.0 5.7e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Ras family HTH_Tnp_Tc3_2 PF01498.18 KFM60581.1 - 2.2e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60581.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DED PF01335.21 KFM60583.1 - 0.047 14.0 0.2 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 Death effector domain LRR_12 PF18837.1 KFM60583.1 - 0.17 11.5 0.5 0.45 10.2 0.2 1.9 2 0 0 2 2 2 0 Leucine-rich repeat EF-hand_7 PF13499.6 KFM60584.1 - 9.4e-27 93.3 1.9 3.5e-16 59.4 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFM60584.1 - 2e-26 89.5 7.2 1.1e-07 30.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 KFM60584.1 - 1.4e-22 78.1 7.4 2.1e-06 26.9 0.5 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFM60584.1 - 2.6e-22 76.8 2.9 2.9e-06 26.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFM60584.1 - 2.3e-14 53.0 7.9 2.1e-06 27.5 0.3 3.8 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM60584.1 - 1.7e-06 28.3 0.6 0.016 15.5 0.1 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFM60584.1 - 0.0014 18.5 1.0 2.4 8.2 0.0 3.4 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFM60584.1 - 0.039 14.1 0.2 7.3 6.9 0.0 2.8 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_10 PF14788.6 KFM60584.1 - 0.19 11.6 3.0 18 5.3 0.0 3.3 4 0 0 4 4 4 0 EF hand SecD-TM1 PF13721.6 KFM60585.1 - 1.4 9.4 4.1 2.2 8.8 3.4 1.6 1 1 0 1 1 1 0 SecD export protein N-terminal TM region ATP_Ca_trans_C PF12424.8 KFM60585.1 - 8.2 7.0 6.9 58 4.3 0.1 3.5 3 0 0 3 3 3 0 Plasma membrane calcium transporter ATPase C terminal Thyroglobulin_1 PF00086.18 KFM60586.1 - 1.5e-20 72.6 7.7 2.4e-11 43.1 1.3 2.2 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat NDUF_B7 PF05676.13 KFM60586.1 - 0.47 10.2 6.4 0.58 9.9 0.4 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Thyroglobulin_1 PF00086.18 KFM60587.1 - 1.3e-09 37.6 22.4 1.2e-06 28.1 8.5 2.2 1 1 1 2 2 2 2 Thyroglobulin type-1 repeat Thyroglobulin_1 PF00086.18 KFM60588.1 - 2.8e-20 71.7 13.2 1.6e-10 40.5 6.5 2.2 1 1 1 2 2 2 2 Thyroglobulin type-1 repeat PepSY_2 PF13670.6 KFM60588.1 - 0.25 11.3 0.9 4.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain TED_complement PF07678.14 KFM60589.1 - 4.2e-88 295.4 0.1 1.1e-87 294.0 0.1 1.7 1 1 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 KFM60589.1 - 6.2e-27 93.3 0.1 1.5e-26 92.1 0.1 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFM60589.1 - 2.5e-26 92.2 0.1 7.6e-26 90.6 0.1 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain NTR PF01759.21 KFM60589.1 - 6.4e-16 58.1 0.1 1.7e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 UNC-6/NTR/C345C module ANATO PF01821.18 KFM60589.1 - 0.00011 23.0 0.5 0.00026 21.8 0.5 1.7 1 0 0 1 1 1 1 Anaphylotoxin-like domain SQHop_cyclase_C PF13243.6 KFM60589.1 - 0.00062 18.9 0.0 0.0027 16.9 0.0 2.0 2 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain DUF3416 PF11896.8 KFM60589.1 - 0.026 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Prenyltrans PF00432.21 KFM60589.1 - 0.16 11.7 0.1 29 4.5 0.0 2.8 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Med26 PF08711.11 KFM60590.1 - 1.7e-16 60.0 2.5 1.7e-16 60.0 2.5 1.7 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TFIIS_M PF07500.14 KFM60591.1 - 2e-33 115.2 0.7 2.6e-33 114.9 0.7 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFM60591.1 - 7.7e-19 67.3 6.3 1.3e-18 66.6 6.3 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Ribonuc_P_40 PF08584.11 KFM60592.1 - 6.4e-33 114.3 0.1 8.2e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit DnaJ PF00226.31 KFM60593.1 - 5e-27 93.8 0.1 5.7e-27 93.6 0.1 1.0 1 0 0 1 1 1 1 DnaJ domain zf-H2C2_2 PF13465.6 KFM60594.1 - 9.4e-108 348.3 103.5 4.7e-09 36.3 0.9 14.1 14 0 0 14 14 14 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60594.1 - 6.1e-59 193.3 129.4 9.9e-06 25.7 3.2 15.1 15 0 0 15 15 15 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60594.1 - 5.1e-43 142.0 113.0 0.0017 19.0 0.8 14.9 15 0 0 15 15 15 13 C2H2-type zinc finger zf-met PF12874.7 KFM60594.1 - 2.3e-33 113.6 87.8 0.0014 19.0 2.5 13.7 13 0 0 13 13 13 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60594.1 - 6.2e-30 102.8 60.7 0.017 15.4 0.1 13.5 13 0 0 13 13 13 12 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM60594.1 - 4.7e-20 71.0 77.7 0.0097 15.6 0.8 14.3 14 0 0 14 14 14 11 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM60594.1 - 1.9e-11 43.5 64.8 0.06 13.1 0.1 12.4 12 0 0 12 12 12 6 zinc-finger C2H2-type zf-Dof PF02701.15 KFM60594.1 - 1.8e-08 34.4 41.9 0.2 11.8 0.1 10.9 3 3 5 9 9 9 4 Dof domain, zinc finger zf-C2H2_6 PF13912.6 KFM60594.1 - 2e-08 34.0 80.8 0.0018 18.2 0.9 13.9 13 1 0 13 13 13 5 C2H2-type zinc finger zf-RRPl_C4 PF17026.5 KFM60594.1 - 2.1e-08 34.2 51.6 0.032 14.3 5.4 6.0 1 1 3 5 5 5 5 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM60594.1 - 7.4e-08 32.4 51.1 4.4 7.5 0.1 13.2 13 0 0 13 13 13 2 DBF zinc finger Tox-HNH-HHH PF15637.6 KFM60594.1 - 1.7e-07 31.3 6.4 3.9 7.7 0.1 6.8 1 1 8 9 9 9 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zinc_ribbon_15 PF17032.5 KFM60594.1 - 7.5e-06 26.6 54.2 0.71 10.7 1.2 6.9 1 1 8 10 10 10 8 zinc-ribbon family GAGA PF09237.11 KFM60594.1 - 1.2e-05 25.0 32.6 0.57 10.0 0.1 9.7 1 1 11 13 13 13 4 GAGA factor DUF2256 PF10013.9 KFM60594.1 - 1.3e-05 25.2 52.7 11 6.3 0.2 13.1 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4806 PF16064.5 KFM60594.1 - 3.2e-05 24.1 12.9 2.3 8.6 0.1 6.7 1 1 5 7 7 7 2 Domain of unknown function (DUF4806) Prok-RING_1 PF14446.6 KFM60594.1 - 5.3e-05 23.1 50.6 5.6 7.0 0.1 12.9 13 0 0 13 13 13 1 Prokaryotic RING finger family 1 A_deaminase PF00962.22 KFM60594.1 - 0.0054 16.1 26.4 0.27 10.5 0.6 6.0 1 1 4 6 6 6 2 Adenosine/AMP deaminase zf-C2H2_9 PF16293.5 KFM60594.1 - 0.0057 16.5 53.3 12 5.8 0.0 12.2 2 2 11 13 13 13 0 C2H2 type zinc-finger (1 copy) DUF2992 PF11208.8 KFM60594.1 - 0.035 14.3 6.7 20 5.4 0.3 5.3 1 1 2 5 5 5 0 Protein of unknown function (DUF2992) Ring_hydroxyl_B PF00866.18 KFM60594.1 - 0.041 14.0 0.2 13 5.8 0.0 4.0 2 2 1 4 4 4 0 Ring hydroxylating beta subunit NAD_kinase PF01513.21 KFM60594.1 - 0.067 12.4 9.0 9.5 5.3 0.3 5.1 1 1 2 3 3 3 0 ATP-NAD kinase SKA2 PF16740.5 KFM60594.1 - 0.068 13.0 13.7 31 4.4 0.1 7.0 1 1 6 8 8 8 0 Spindle and kinetochore-associated protein 2 DUF4712 PF15830.5 KFM60594.1 - 0.07 12.8 1.1 0.49 10.0 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4712) zf-C2H2_2 PF12756.7 KFM60594.1 - 0.086 13.2 97.8 2 8.8 2.8 11.4 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) PEMT PF04191.13 KFM60594.1 - 6 7.3 5.4 37 4.8 0.0 4.9 8 0 0 8 8 5 0 Phospholipid methyltransferase zf-H2C2_2 PF13465.6 KFM60595.1 - 6.3e-72 235.0 56.0 2.7e-08 33.9 2.0 10.1 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60595.1 - 1.8e-38 128.9 81.4 7.2e-06 26.2 1.9 9.8 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60595.1 - 1.4e-31 106.5 75.8 0.00089 19.9 1.7 9.8 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFM60595.1 - 4e-17 62.0 71.4 0.0082 16.5 1.3 10.0 10 1 1 11 11 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60595.1 - 9e-12 45.0 45.4 0.17 12.2 0.8 9.5 9 0 0 9 9 9 7 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM60595.1 - 5.8e-09 35.6 16.0 0.038 13.8 0.2 6.4 3 2 4 7 7 7 4 GAGA factor zf-C2H2_6 PF13912.6 KFM60595.1 - 2.6e-08 33.7 69.8 0.0084 16.1 0.6 10.2 10 1 0 10 10 9 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM60595.1 - 4e-07 29.7 51.4 0.13 12.1 0.5 10.2 10 0 0 10 10 10 5 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM60595.1 - 1.4e-06 28.2 30.7 2.8 8.0 0.3 9.0 7 2 2 9 9 9 2 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM60595.1 - 2.4e-06 27.4 23.6 0.57 10.2 1.6 6.4 1 1 5 6 6 6 4 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM60595.1 - 5.4e-06 26.2 34.9 0.93 9.5 0.3 9.3 9 0 0 9 9 9 2 zinc-finger of a C2HC-type Tox-HNH-HHH PF15637.6 KFM60595.1 - 0.00058 20.0 1.0 1 9.5 0.1 3.7 2 1 1 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif BolA PF01722.18 KFM60595.1 - 0.0015 18.7 9.7 5.4 7.4 1.3 5.0 1 1 3 5 5 5 2 BolA-like protein zf_UBZ PF18439.1 KFM60595.1 - 0.013 15.1 39.1 1.9 8.1 0.2 9.1 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 KFM60595.1 - 0.025 14.8 7.1 0.025 14.8 7.1 6.3 1 1 7 8 8 5 0 TFIIH C1-like domain zinc_ribbon_15 PF17032.5 KFM60595.1 - 0.054 14.2 29.1 0.5 11.1 0.6 5.0 3 1 1 5 5 5 0 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM60595.1 - 0.07 13.2 34.8 0.028 14.5 6.9 4.2 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM60595.1 - 0.09 12.9 39.4 6.3 7.0 0.4 8.8 9 0 0 9 9 9 0 DBF zinc finger TMEM70 PF06979.12 KFM60595.1 - 0.13 12.7 2.0 15 6.0 0.2 3.4 2 1 1 3 3 3 0 Assembly, mitochondrial proton-transport ATP synth complex Zn-ribbon_8 PF09723.10 KFM60595.1 - 0.15 12.2 29.2 0.46 10.6 1.0 5.7 3 1 3 6 6 6 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 KFM60595.1 - 0.2 11.5 37.7 4.1 7.3 0.7 8.8 2 2 7 9 9 9 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM60595.1 - 0.2 11.8 48.0 1.2 9.3 7.6 5.4 1 1 3 4 4 3 0 FYVE zinc finger C1_1 PF00130.22 KFM60595.1 - 0.56 10.1 51.8 8.9 6.3 1.0 7.9 2 2 5 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MYST PF17772.1 KFM60595.1 - 0.74 9.5 46.3 2.1 8.0 0.4 8.5 3 2 6 9 9 9 0 MYST family zinc finger domain PqqA PF08042.11 KFM60595.1 - 2.6 8.2 4.8 4.5e+02 1.1 0.0 5.2 7 0 0 7 7 7 0 PqqA family SPARC_Ca_bdg PF10591.9 KFM60595.1 - 4.7 7.6 14.2 2.1 8.7 0.7 4.4 3 2 2 5 5 5 0 Secreted protein acidic and rich in cysteine Ca binding region zf-C2H2 PF00096.26 KFM60596.1 - 7.7e-18 63.9 23.5 6.6e-07 29.4 0.8 3.7 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM60596.1 - 8.6e-14 51.2 23.5 2.7e-07 30.7 0.3 3.8 4 1 0 4 4 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM60596.1 - 3.4e-13 49.2 20.8 8.1e-05 23.1 0.5 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM60596.1 - 6.7e-07 29.2 22.3 0.0038 17.2 3.7 4.1 3 1 0 3 3 3 3 C2H2-type zinc finger XPA_N PF01286.18 KFM60596.1 - 2.4e-06 27.5 8.0 0.11 12.5 2.9 3.2 3 0 0 3 3 3 3 XPA protein N-terminal zf-met PF12874.7 KFM60596.1 - 7.9e-06 26.1 15.4 0.019 15.3 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60596.1 - 1.1e-05 25.5 12.2 0.011 16.0 0.1 3.5 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM60596.1 - 0.00028 21.2 12.0 0.1 13.0 0.5 3.0 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFM60596.1 - 0.00052 19.7 13.6 0.5 10.2 0.3 3.4 3 0 0 3 3 3 2 zinc-finger C2H2-type zf_UBZ PF18439.1 KFM60596.1 - 0.00072 19.1 2.6 1.1 9.0 0.1 3.3 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM60596.1 - 0.0014 18.7 6.8 0.14 12.3 0.4 2.6 2 1 1 3 3 3 2 Zinc ribbon domain zf-BED PF02892.15 KFM60596.1 - 0.0017 18.3 16.1 0.0093 16.0 0.8 3.3 1 1 2 3 3 3 2 BED zinc finger DUF2256 PF10013.9 KFM60596.1 - 0.0039 17.3 4.4 2.6 8.2 0.0 3.1 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFM60596.1 - 0.0047 16.8 14.8 0.15 12.0 2.7 3.2 3 0 0 3 3 3 2 zinc-finger of a C2HC-type HypA PF01155.19 KFM60596.1 - 0.01 15.9 4.0 0.71 9.9 0.4 2.2 1 1 2 3 3 3 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 KFM60596.1 - 0.012 16.3 1.6 0.012 16.3 1.6 2.0 1 1 1 2 2 2 0 zinc-ribbon family HNH_5 PF14279.6 KFM60596.1 - 0.026 14.4 2.9 0.92 9.4 1.3 3.0 2 1 0 2 2 2 0 HNH endonuclease zf-HIT PF04438.16 KFM60596.1 - 0.057 13.3 9.7 0.71 9.8 0.6 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-LYAR PF08790.11 KFM60596.1 - 0.14 12.1 7.0 4.9 7.1 0.1 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 KFM60596.1 - 0.14 12.4 9.6 0.093 13.0 4.3 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 KFM60596.1 - 0.14 12.1 7.3 2 8.4 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFM60596.1 - 0.15 12.1 6.0 0.58 10.2 2.3 2.6 1 1 2 3 3 3 0 zinc-ribbons TFIIS_C PF01096.18 KFM60596.1 - 0.16 11.8 6.2 6.5 6.7 0.4 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) CpXC PF14353.6 KFM60596.1 - 0.17 11.9 5.8 5.7 7.0 0.3 3.0 1 1 2 3 3 3 0 CpXC protein LIM PF00412.22 KFM60596.1 - 0.18 12.0 11.2 0.55 10.5 7.4 2.5 2 1 0 2 2 2 0 LIM domain zf-C2HE PF16278.5 KFM60596.1 - 0.19 12.2 16.8 0.28 11.6 0.6 3.4 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DZR PF12773.7 KFM60596.1 - 0.19 11.7 7.9 5.6 7.1 7.9 2.3 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 KFM60596.1 - 0.21 11.9 7.4 9.2 6.6 1.3 3.2 3 0 0 3 3 3 0 zinc-ribbon Elf1 PF05129.13 KFM60596.1 - 0.37 10.9 6.9 0.26 11.4 2.4 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like SIR2 PF02146.17 KFM60596.1 - 0.39 10.6 3.6 0.9 9.4 0.7 2.0 1 1 1 2 2 2 0 Sir2 family zf_C2H2_13 PF18508.1 KFM60596.1 - 0.48 10.1 7.2 20 4.9 1.3 3.2 2 1 1 3 3 3 0 Zinc finger domain Zn_ribbon_recom PF13408.6 KFM60596.1 - 1.7 9.2 9.8 5.1 7.7 4.8 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-trcl PF13451.6 KFM60596.1 - 1.8 8.5 8.6 23 5.0 0.1 3.2 3 1 0 3 3 3 0 Probable zinc-ribbon domain Desulfoferrod_N PF06397.12 KFM60596.1 - 2 8.1 8.5 3.2 7.5 0.1 3.1 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain Zn_Tnp_IS1595 PF12760.7 KFM60596.1 - 2.4 8.2 13.1 1.6 8.8 2.8 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 KFM60596.1 - 2.9 7.4 8.2 18 4.9 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KFM60596.1 - 4 7.2 9.4 16 5.3 0.4 3.2 3 0 0 3 3 3 0 Rubredoxin metal binding domain NUDIX_2 PF13869.6 KFM60597.1 - 9e-79 263.4 0.0 1e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 KFM60597.1 - 0.066 13.3 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain DUF4758 PF15950.5 KFM60598.1 - 2.2e-15 57.2 0.2 2.2e-15 57.2 0.2 4.6 4 1 1 5 5 5 1 Putative sperm flagellar membrane protein HTH_Tnp_Tc3_2 PF01498.18 KFM60599.1 - 1.9e-16 60.0 2.2 3.9e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60599.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ig_3 PF13927.6 KFM60601.1 - 2.5e-14 53.6 0.1 2.8e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM60601.1 - 1.7e-13 50.4 0.0 1.9e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM60601.1 - 4.6e-11 42.8 0.0 5.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM60601.1 - 8.8e-09 35.6 0.1 1e-08 35.4 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM60601.1 - 6.8e-08 32.7 0.1 0.0043 17.2 0.0 2.1 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM60601.1 - 4e-05 23.9 0.0 5.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM60601.1 - 0.019 15.0 0.1 0.029 14.4 0.1 1.4 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM60601.1 - 0.023 15.0 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Peptidase_S26 PF10502.9 KFM60601.1 - 0.082 12.7 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 Transposase_1 PF01359.18 KFM60602.1 - 9.2e-27 92.7 1.2 1.1e-26 92.5 0.2 1.6 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM60602.1 - 3.1e-13 49.6 0.2 6.3e-13 48.6 0.2 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DDE_3 PF13358.6 KFM60602.1 - 2.4e-07 30.6 0.1 3.9e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_50 PF18024.1 KFM60602.1 - 2.3e-05 23.9 0.0 4.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM60602.1 - 0.00065 19.9 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_11 PF08279.12 KFM60602.1 - 0.0033 17.3 0.1 0.0086 16.0 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_10 PF04967.12 KFM60602.1 - 0.044 13.6 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain GerE PF00196.19 KFM60602.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 KFM60602.1 - 0.056 13.6 0.1 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 KFM60602.1 - 0.062 13.2 0.1 0.29 11.1 0.2 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 KFM60602.1 - 0.15 11.9 0.1 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain Ribosomal_L7Ae PF01248.26 KFM60603.1 - 6e-23 80.4 0.3 1.2e-22 79.4 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Metal_resist PF13801.6 KFM60603.1 - 0.16 12.1 4.0 0.3 11.3 2.1 2.0 2 0 0 2 2 2 0 Heavy-metal resistance RNA_pol_I_A49 PF06870.12 KFM60605.1 - 4.5e-58 196.9 2.3 5.6e-58 196.6 2.3 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor PulA_N1 PF17999.1 KFM60605.1 - 0.039 14.7 0.6 1.2 9.9 0.0 3.1 2 1 1 3 3 3 0 Pullulanase N1-terminal domain MRNIP PF15749.5 KFM60606.1 - 1.1e-25 90.4 19.9 5.5e-25 88.2 20.0 2.0 1 1 0 1 1 1 1 MRN-interacting protein IL28A PF15177.6 KFM60606.1 - 0.0076 16.1 1.1 0.019 14.8 0.2 2.0 1 1 0 2 2 2 1 Interleukin-28A zf-MIZ PF02891.20 KFM60606.1 - 0.054 13.2 4.0 0.12 12.2 4.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.15 KFM60606.1 - 0.062 13.4 5.2 1.1 9.3 3.3 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger VWD PF00094.25 KFM60607.1 - 7.8e-38 130.2 0.2 5.4e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 KFM60607.1 - 7.2e-19 68.0 17.6 1.3e-11 44.7 1.5 4.2 4 0 0 4 4 4 2 C8 domain TIL PF01826.17 KFM60607.1 - 5.3e-17 61.8 37.9 3.7e-13 49.5 17.0 4.5 4 1 0 4 4 4 2 Trypsin Inhibitor like cysteine rich domain Cwf_Cwc_15 PF04889.12 KFM60608.1 - 1e-39 136.8 8.8 1.1e-39 136.7 8.8 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Atrophin-1 PF03154.15 KFM60608.1 - 5.9 5.1 7.8 7.6 4.7 7.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family DND1_DSRM PF14709.7 KFM60609.1 - 8.1e-12 45.2 0.0 1.6e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_1 PF00076.22 KFM60609.1 - 1.1e-09 37.9 0.0 1.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPV_P10 PF05531.12 KFM60610.1 - 9e-05 22.9 19.4 0.17 12.4 0.6 4.7 1 1 3 4 4 4 3 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KFM60610.1 - 0.00016 21.7 11.1 0.0027 17.8 0.2 3.7 1 1 3 4 4 4 1 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KFM60610.1 - 0.00072 19.6 17.3 0.028 14.4 10.3 3.3 1 1 3 4 4 4 1 Laminin Domain II ADIP PF11559.8 KFM60610.1 - 0.00077 19.6 1.5 0.00077 19.6 1.5 3.1 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding DUF2730 PF10805.8 KFM60610.1 - 0.0027 17.8 0.5 0.0027 17.8 0.5 4.0 3 2 1 4 4 3 1 Protein of unknown function (DUF2730) DUF948 PF06103.11 KFM60610.1 - 0.0036 17.5 11.0 4.5 7.6 0.5 3.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) HOOK PF05622.12 KFM60610.1 - 0.0044 15.3 10.7 0.0054 14.9 10.7 1.3 1 0 0 1 1 1 1 HOOK protein Spc7 PF08317.11 KFM60610.1 - 0.0066 15.4 14.4 0.064 12.1 5.1 2.5 2 1 1 3 3 3 2 Spc7 kinetochore protein DUF4763 PF15960.5 KFM60610.1 - 0.0068 15.7 2.8 0.0068 15.7 2.8 3.0 2 1 2 4 4 3 1 Domain of unknown function (DUF4763) Seryl_tRNA_N PF02403.22 KFM60610.1 - 0.013 15.7 9.1 0.039 14.2 4.7 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.9 KFM60610.1 - 0.019 15.7 5.0 1.4 9.7 0.4 3.6 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) MCPsignal PF00015.21 KFM60610.1 - 0.034 14.0 9.6 1.6 8.5 4.3 2.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DHR10 PF18595.1 KFM60610.1 - 0.061 13.4 3.7 0.2 11.7 2.7 2.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 KFM60610.1 - 0.062 13.5 20.4 0.055 13.7 1.0 3.8 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 KFM60610.1 - 0.089 13.5 4.1 14 6.5 1.1 4.0 1 1 3 4 4 4 0 Occludin homology domain CREPT PF16566.5 KFM60610.1 - 0.095 12.9 7.6 0.66 10.1 6.9 2.4 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CdvA PF18822.1 KFM60610.1 - 0.13 12.1 8.3 0.59 10.0 2.6 3.7 3 1 0 3 3 3 0 CdvA-like coiled-coil domain Snapin_Pallidin PF14712.6 KFM60610.1 - 0.13 12.6 15.4 0.12 12.8 5.0 4.2 1 1 3 4 4 4 0 Snapin/Pallidin HAUS-augmin3 PF14932.6 KFM60610.1 - 0.17 11.4 8.5 0.29 10.7 7.4 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FliD_N PF02465.18 KFM60610.1 - 0.26 12.0 12.5 5 7.9 6.2 3.2 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Fez1 PF06818.15 KFM60610.1 - 0.34 11.4 10.9 0.17 12.3 6.9 2.5 2 1 0 2 2 1 0 Fez1 Spectrin PF00435.21 KFM60610.1 - 0.37 11.3 7.8 1.4 9.4 1.3 3.4 2 1 1 3 3 2 0 Spectrin repeat KASH_CCD PF14662.6 KFM60610.1 - 0.56 10.0 17.9 0.67 9.8 6.2 2.8 2 1 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH GCN5L1 PF06320.13 KFM60610.1 - 0.58 10.3 8.6 5.6 7.1 1.7 3.4 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF4140 PF13600.6 KFM60610.1 - 0.63 10.5 3.2 2 8.9 2.1 2.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KFM60610.1 - 0.64 10.6 8.0 5.7 7.5 6.0 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Sec34 PF04136.15 KFM60610.1 - 0.65 9.9 14.3 0.41 10.5 3.7 3.6 2 1 2 4 4 4 0 Sec34-like family DASH_Dam1 PF08653.10 KFM60610.1 - 0.83 9.5 8.6 10 6.0 0.3 4.6 2 1 2 4 4 4 0 DASH complex subunit Dam1 FlaC_arch PF05377.11 KFM60610.1 - 1.1 9.7 15.8 8.1 6.9 3.0 5.9 2 1 3 5 5 5 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 KFM60610.1 - 1.2 9.6 9.0 0.47 10.9 1.5 3.8 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LPP PF04728.13 KFM60610.1 - 1.9 9.0 12.8 1.4 9.4 0.7 4.5 1 1 3 4 4 4 0 Lipoprotein leucine-zipper TMPIT PF07851.13 KFM60610.1 - 2.1 7.5 13.1 0.11 11.7 4.1 2.6 2 1 0 3 3 3 0 TMPIT-like protein ZapB PF06005.12 KFM60610.1 - 2.1 8.9 12.6 0.63 10.5 1.0 3.7 2 1 2 4 4 3 0 Cell division protein ZapB FapA PF03961.13 KFM60610.1 - 2.2 6.8 15.3 0.052 12.1 6.3 2.4 2 1 1 3 3 3 0 Flagellar Assembly Protein A DivIC PF04977.15 KFM60610.1 - 2.3 8.0 7.7 1.5 8.6 0.4 3.6 4 0 0 4 4 3 0 Septum formation initiator DivIVA PF05103.13 KFM60610.1 - 2.4 8.3 9.4 11 6.1 2.1 2.9 1 1 1 2 2 2 0 DivIVA protein Jnk-SapK_ap_N PF09744.9 KFM60610.1 - 3.2 8.0 11.5 5.7 7.1 0.4 3.1 2 1 1 3 3 2 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 KFM60610.1 - 3.5 7.6 13.6 0.57 10.2 3.6 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 KFM60610.1 - 3.7 7.7 9.0 1.5 9.0 0.2 4.2 4 1 1 5 5 3 0 bZIP transcription factor Syntaxin-6_N PF09177.11 KFM60610.1 - 4.2 8.0 8.6 24 5.5 5.5 3.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal zf-C4H2 PF10146.9 KFM60610.1 - 4.2 7.6 16.3 1.3 9.2 1.5 3.1 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4472 PF14739.6 KFM60610.1 - 5.3 7.8 9.0 2.3 9.0 2.5 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4472) DUF724 PF05266.14 KFM60610.1 - 5.7 6.7 8.9 1.2 8.9 1.9 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF724) K-box PF01486.17 KFM60610.1 - 5.7 7.2 10.4 6.2 7.1 1.4 3.7 3 2 0 3 3 3 0 K-box region DUF4795 PF16043.5 KFM60610.1 - 6.5 6.3 17.4 0.15 11.7 6.2 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4795) DUF16 PF01519.16 KFM60610.1 - 9.3 6.8 17.7 2.9 8.4 6.5 3.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 HTH_Tnp_Tc3_2 PF01498.18 KFM60611.1 - 4.8e-16 58.8 3.5 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60611.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60611.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60611.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60611.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DnaJ_C PF01556.18 KFM60612.1 - 1.2e-41 142.3 0.1 1.5e-41 141.9 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFM60612.1 - 2.9e-26 91.4 1.8 6.5e-26 90.3 1.8 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFM60612.1 - 4.9e-15 55.6 15.1 8.3e-15 54.9 15.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFM60612.1 - 0.025 14.5 9.3 1.1 9.2 1.4 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFM60612.1 - 0.034 14.1 6.2 0.36 10.9 1.4 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KFM60612.1 - 0.43 10.2 4.1 5.3 6.7 0.4 2.3 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 DUF2614 PF11023.8 KFM60612.1 - 1.5 8.9 5.0 0.57 10.3 0.3 2.1 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc-ribbons_6 PF07191.12 KFM60612.1 - 1.7 8.7 6.2 4.4 7.3 3.8 2.3 1 1 1 2 2 2 0 zinc-ribbons DUF2039 PF10217.9 KFM60612.1 - 3.2 8.2 7.0 2.3 8.6 0.1 3.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2039) Trypsin PF00089.26 KFM60613.1 - 4.6e-26 92.0 0.0 6.2e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM60613.1 - 2.6e-05 24.6 0.0 4.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFM60613.1 - 0.00011 23.1 0.0 0.00016 22.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF3927 PF13064.6 KFM60616.1 - 0.47 10.5 3.5 1.5 8.8 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3927) zf-H2C2_2 PF13465.6 KFM60618.1 - 1.4e-48 161.3 60.9 9.7e-08 32.1 2.4 9.2 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60618.1 - 1.7e-37 125.8 74.8 1.8e-05 24.9 1.2 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60618.1 - 1.2e-25 87.9 69.7 0.00037 21.1 0.9 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM60618.1 - 6.8e-22 77.0 58.4 7.3e-06 25.8 0.2 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM60618.1 - 2.2e-19 69.1 61.9 0.0003 21.1 1.0 8.3 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60618.1 - 1.5e-13 50.6 47.6 0.12 12.7 0.2 8.4 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM60618.1 - 1.3e-08 34.6 20.9 0.007 16.3 2.0 4.7 4 1 0 4 4 4 3 Adenylate kinase, active site lid GAGA PF09237.11 KFM60618.1 - 1.7e-05 24.5 20.5 0.03 14.1 0.2 5.6 4 3 1 5 5 5 2 GAGA factor BHD_1 PF10403.9 KFM60618.1 - 0.00025 20.8 1.7 1.2 9.0 0.0 3.7 3 1 1 4 4 4 2 Rad4 beta-hairpin domain 1 zf-C2H2_8 PF15909.5 KFM60618.1 - 0.012 15.9 37.8 0.25 11.7 4.9 5.4 1 1 4 5 5 5 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KFM60618.1 - 0.021 14.9 26.1 2.6 8.2 2.5 5.1 4 2 0 4 4 4 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFM60618.1 - 0.027 14.4 33.4 0.95 9.4 0.0 8.2 8 0 0 8 8 8 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM60618.1 - 0.027 14.6 28.9 16 5.7 0.1 8.2 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_ZIC PF18366.1 KFM60618.1 - 0.035 14.2 5.0 0.035 14.2 5.0 7.0 5 3 3 8 8 8 0 Zic proteins zinc finger domain zf-H2C2_5 PF13909.6 KFM60618.1 - 0.038 13.8 55.7 0.058 13.2 0.7 8.4 9 0 0 9 9 8 0 C2H2-type zinc-finger domain BolA PF01722.18 KFM60618.1 - 0.054 13.8 15.9 1.1 9.6 0.2 5.2 2 2 2 5 5 5 0 BolA-like protein HEPPP_synt_1 PF07307.11 KFM60618.1 - 0.054 13.1 0.2 0.26 10.8 0.1 1.8 1 1 1 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 zf_UBZ PF18439.1 KFM60618.1 - 0.12 12.0 30.8 14 5.4 0.1 8.0 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger CTV_P23 PF04808.12 KFM60618.1 - 0.22 11.1 4.1 1.7 8.1 0.2 2.4 1 1 0 2 2 2 0 Citrus tristeza virus (CTV) P23 protein zf-C2H2_2 PF12756.7 KFM60618.1 - 0.49 10.8 54.2 1.2 9.5 5.1 6.7 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM60619.1 - 1.4e-81 265.6 90.9 1.2e-09 38.1 0.8 13.9 14 1 0 14 14 13 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60619.1 - 1.6e-60 198.3 114.0 1.3e-05 25.4 1.8 13.1 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60619.1 - 2.3e-45 149.3 105.3 0.00016 22.2 1.0 13.2 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM60619.1 - 4.4e-38 128.6 74.5 4e-05 23.5 0.5 13.3 13 0 0 13 13 13 11 C2H2-type zinc finger zf-met PF12874.7 KFM60619.1 - 1.2e-33 114.5 92.4 0.002 18.4 1.3 13.3 13 0 0 13 13 13 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM60619.1 - 2.2e-20 72.4 75.8 0.083 13.2 0.2 13.3 13 0 0 13 13 13 12 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM60619.1 - 1.1e-13 50.7 70.2 0.0043 16.8 0.5 12.0 12 0 0 12 12 12 8 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM60619.1 - 1.1e-07 31.7 52.4 0.064 13.2 1.0 8.4 7 1 1 8 8 7 5 Adenylate kinase, active site lid GAGA PF09237.11 KFM60619.1 - 1.9e-06 27.6 28.8 0.016 15.0 0.2 8.5 4 3 3 9 9 9 2 GAGA factor zf-C2HC_2 PF13913.6 KFM60619.1 - 6.8e-06 25.9 48.4 1.1 9.3 0.0 12.6 13 0 0 13 13 13 2 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM60619.1 - 0.00028 20.4 50.8 5.2 6.8 0.3 12.7 13 0 0 13 13 13 1 Ubiquitin-Binding Zinc Finger BolA PF01722.18 KFM60619.1 - 0.00048 20.3 23.2 14 6.1 0.0 8.2 1 1 5 6 6 6 0 BolA-like protein zf-RRPl_C4 PF17026.5 KFM60619.1 - 0.00052 20.1 49.3 0.13 12.3 5.5 6.1 1 1 5 6 6 6 3 Putative ribonucleoprotein zinc-finger pf C4 type DUF952 PF06108.12 KFM60619.1 - 0.0013 18.7 2.5 0.51 10.4 0.0 3.3 4 0 0 4 4 3 1 Protein of unknown function (DUF952) BHD_1 PF10403.9 KFM60619.1 - 0.0025 17.6 0.9 23 4.9 0.0 4.4 4 1 0 4 4 4 0 Rad4 beta-hairpin domain 1 zf-C2H2_11 PF16622.5 KFM60619.1 - 0.0039 16.9 2.0 0.0039 16.9 2.0 7.0 7 0 0 7 7 6 3 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFM60619.1 - 0.0065 16.8 80.3 0.64 10.4 9.4 9.7 1 1 7 8 8 8 4 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM60619.1 - 0.012 15.2 60.2 0.84 9.3 0.2 11.6 6 5 7 13 13 13 0 MYST family zinc finger domain TFA2_Winged_2 PF18121.1 KFM60619.1 - 0.16 11.7 0.9 8.2 6.2 0.0 3.1 4 0 0 4 4 4 0 TFA2 Winged helix domain 2 Zn-ribbon_8 PF09723.10 KFM60619.1 - 0.54 10.4 41.5 2.1 8.6 0.8 7.8 5 2 3 8 8 8 0 Zinc ribbon domain RYDR_ITPR PF01365.21 KFM60619.1 - 0.62 9.5 9.4 2.1 7.7 0.3 3.6 1 1 3 4 4 4 0 RIH domain Prok-RING_2 PF14445.6 KFM60619.1 - 0.71 10.1 41.5 8.9 6.6 0.1 11.3 10 3 2 12 12 12 0 Prokaryotic RING finger family 2 C5HCH PF17982.1 KFM60619.1 - 0.88 9.8 59.8 4.6 7.5 0.1 12.4 9 2 3 13 13 13 0 NSD Cys-His rich domain GNAT_C PF18164.1 KFM60619.1 - 3.5 7.3 15.8 0.76 9.5 0.6 4.3 2 1 1 4 4 4 0 GNAT-like C-terminal domain zinc_ribbon_15 PF17032.5 KFM60619.1 - 3.8 8.3 49.2 0.61 10.9 0.7 7.2 1 1 7 8 8 8 0 zinc-ribbon family CTV_P23 PF04808.12 KFM60619.1 - 4.1 6.9 10.6 5.3 6.5 0.0 3.6 1 1 1 3 3 3 0 Citrus tristeza virus (CTV) P23 protein Prok-RING_1 PF14446.6 KFM60619.1 - 5.4 7.0 53.0 7.8 6.5 0.2 12.2 12 1 0 12 12 12 0 Prokaryotic RING finger family 1 RNA_pol_Rpb1_1 PF04997.12 KFM60620.1 - 3.6e-84 282.7 6.5 5.8e-84 282.1 6.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KFM60620.1 - 1.4e-73 246.6 0.1 4.1e-73 245.1 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFM60620.1 - 6.2e-39 133.4 0.1 4.1e-38 130.8 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFM60620.1 - 0.0017 18.3 0.0 0.0044 16.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF4363 PF14276.6 KFM60620.1 - 0.13 12.4 1.3 0.56 10.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) RNA_pol_Rpb1_5 PF04998.17 KFM60621.1 - 5.4e-63 212.9 0.0 6.5e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 KFM60621.1 - 3.2e-12 46.3 0.0 9.4e-12 44.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RVT_1 PF00078.27 KFM60622.1 - 3.3e-31 108.5 0.0 4.3e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.18 KFM60623.1 - 4.7e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60623.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60623.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60623.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60623.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Transposase_1 PF01359.18 KFM60624.1 - 5.4e-14 51.8 0.4 1.2e-13 50.7 0.1 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM60624.1 - 1e-08 35.0 0.1 1.6e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 KFM60625.1 - 4.5e-72 242.6 0.0 7.4e-72 241.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM60625.1 - 1.3e-28 100.0 0.0 2.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFM60625.1 - 1.1e-20 74.0 6.3 2.3e-20 73.0 6.3 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.29 KFM60625.1 - 3e-07 30.9 0.0 7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KFM60625.1 - 0.00033 20.1 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM60625.1 - 0.0041 15.9 0.0 0.0097 14.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase PTE PF02126.18 KFM60626.1 - 0.014 14.9 0.0 0.015 14.8 0.0 1.0 1 0 0 1 1 1 0 Phosphotriesterase family MFS_1 PF07690.16 KFM60628.1 - 4.2e-11 42.4 48.9 1.1e-08 34.4 10.1 2.9 1 1 0 3 3 3 2 Major Facilitator Superfamily 2TM PF13239.6 KFM60628.1 - 0.25 11.7 10.3 0.64 10.4 0.5 3.1 2 0 0 2 2 2 0 2TM domain MFS_1 PF07690.16 KFM60629.1 - 6.5e-16 58.2 38.2 2.1e-15 56.5 38.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM60629.1 - 0.0014 17.6 4.1 0.0014 17.6 4.1 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter HTH_Tnp_Tc3_2 PF01498.18 KFM60630.1 - 2.5e-12 46.9 0.8 4.1e-12 46.2 0.8 1.4 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM60630.1 - 0.00022 20.9 0.9 0.001 18.8 0.3 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 KFM60630.1 - 0.0059 16.3 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KFM60630.1 - 0.0088 16.1 0.5 0.0088 16.1 0.5 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM60630.1 - 0.022 14.1 2.4 0.04 13.3 0.3 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 KFM60630.1 - 0.049 13.7 1.4 0.15 12.1 0.1 2.2 2 1 0 2 2 2 0 Winged helix-turn helix HTH_Crp_2 PF13545.6 KFM60630.1 - 0.049 13.6 0.5 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_Tnp_1 PF01527.20 KFM60630.1 - 0.056 13.8 0.4 0.088 13.1 0.4 1.4 1 0 0 1 1 1 0 Transposase DUF4064 PF13273.6 KFM60631.1 - 0.013 15.8 2.0 0.019 15.3 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Spidroin_MaSp PF11260.8 KFM60634.1 - 8.8e-14 51.6 0.4 8.8e-14 51.6 0.4 3.6 3 1 1 4 4 4 1 Major ampullate spidroin 1 and 2 RP1-2 PF12042.8 KFM60634.1 - 4.8e-05 23.3 34.3 0.0023 17.8 7.6 2.8 2 1 0 2 2 2 2 Tubuliform egg casing silk strands structural domain Bunya_RdRp PF04196.12 KFM60634.1 - 0.019 13.4 0.5 0.028 12.8 0.5 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Ig_3 PF13927.6 KFM60636.1 - 4.5e-28 97.7 0.6 1.2e-12 48.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM60636.1 - 1.7e-23 82.8 0.1 1.3e-07 31.8 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM60636.1 - 3.8e-21 75.1 1.3 4.4e-06 26.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM60636.1 - 9e-21 73.8 0.1 3.5e-10 39.8 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFM60636.1 - 3.5e-18 65.4 2.1 1.3e-12 47.6 0.1 3.5 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM60636.1 - 2.3e-06 27.9 0.0 0.00076 19.8 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM60636.1 - 5.9e-06 26.4 0.4 0.0021 18.3 0.0 3.7 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 KFM60636.1 - 0.0003 20.9 1.6 1.2 9.3 0.0 4.4 3 3 1 4 4 4 1 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM60636.1 - 0.026 14.9 1.6 1.2 9.6 0.0 3.3 4 0 0 4 4 4 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 KFM60636.1 - 0.078 12.8 0.2 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Kazal_2 PF07648.15 KFM60637.1 - 1.7e-15 56.8 12.6 2.2e-10 40.5 6.0 2.3 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM60637.1 - 3.1e-10 39.9 12.3 2.8e-06 27.2 3.5 2.3 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain DUF267 PF03268.14 KFM60638.1 - 0.011 14.6 0.2 0.012 14.5 0.2 1.0 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 TRIQK PF15168.6 KFM60638.1 - 0.074 13.0 2.7 0.11 12.4 2.7 1.3 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family YWFCY PF14293.6 KFM60638.1 - 0.21 11.9 2.6 0.36 11.2 2.6 1.4 1 1 0 1 1 1 0 YWFCY protein DNA_topoisoIV PF00521.20 KFM60640.1 - 4.5e-136 454.1 0.3 7.8e-136 453.3 0.3 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KFM60640.1 - 7e-50 168.6 4.1 2.6e-49 166.8 4.1 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KFM60640.1 - 2.3e-28 98.8 1.5 6.2e-28 97.4 1.5 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KFM60640.1 - 6e-15 55.7 0.0 1.5e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KFM60640.1 - 4.5e-08 33.3 0.0 1.6e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DTHCT PF08070.11 KFM60640.1 - 0.0012 19.6 6.2 0.0012 19.6 6.2 7.2 3 2 5 8 8 8 2 DTHCT (NUC029) region RRM_1 PF00076.22 KFM60641.1 - 1.2e-36 124.4 0.3 1.5e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM60641.1 - 5e-16 58.6 0.4 1.8e-07 31.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KFM60641.1 - 0.0086 16.1 0.1 4 7.5 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif PHM7_cyt PF14703.6 KFM60641.1 - 0.024 14.9 0.1 9.9 6.4 0.1 3.3 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RL PF17797.1 KFM60641.1 - 0.071 13.1 0.1 7.2 6.6 0.0 2.2 2 0 0 2 2 2 0 RL domain HTH_Tnp_Tc3_2 PF01498.18 KFM60642.1 - 2.3e-16 59.8 2.8 5.1e-16 58.7 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60642.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60642.1 - 4.2e-07 29.6 1.3 6.4e-07 29.0 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60642.1 - 0.0026 17.5 0.6 0.0069 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60642.1 - 0.029 14.5 0.4 0.082 13.0 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM60642.1 - 2.1 9.0 13.8 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM60643.1 - 3.8e-05 23.2 0.1 4e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 CagS PF16707.5 KFM60643.1 - 0.014 15.5 0.0 0.014 15.4 0.0 1.0 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori zf-H2C2_2 PF13465.6 KFM60645.1 - 1.8e-11 43.9 9.5 3.8e-05 23.9 0.4 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60645.1 - 4e-07 30.1 6.6 0.0002 21.7 0.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60645.1 - 8.7e-07 29.3 5.0 0.00011 22.8 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM60645.1 - 0.00058 20.2 1.4 0.7 10.3 0.2 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM60645.1 - 0.0022 17.7 0.6 0.0022 17.7 0.6 2.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM60645.1 - 0.0056 16.6 0.2 0.0056 16.6 0.2 2.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-BED PF02892.15 KFM60645.1 - 0.013 15.5 9.2 0.064 13.3 1.3 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 KFM60645.1 - 0.026 14.3 1.8 0.026 14.3 1.8 1.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFM60645.1 - 0.035 14.0 0.9 0.053 13.4 0.1 1.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 KFM60645.1 - 0.077 13.5 0.8 1.1 9.7 0.1 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger C1_2 PF03107.16 KFM60645.1 - 0.22 11.9 4.1 5.1 7.5 0.2 2.5 3 0 0 3 3 3 0 C1 domain zf_C2H2_ZHX PF18387.1 KFM60645.1 - 0.39 10.4 2.7 6.9 6.4 0.5 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_7 PF15269.6 KFM60645.1 - 2.1 8.5 7.3 0.34 11.0 2.3 1.9 1 1 1 2 2 2 0 Zinc-finger zf-H2C2_2 PF13465.6 KFM60646.1 - 1.4e-09 37.9 12.9 6.1e-05 23.3 1.4 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM60646.1 - 4.3e-08 33.2 7.3 0.002 18.5 0.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60646.1 - 2.7e-07 30.9 6.4 0.0003 21.4 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM60646.1 - 3.3e-07 29.9 3.9 1.4e-06 27.9 2.0 2.3 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KFM60646.1 - 0.00025 21.4 2.1 0.024 15.1 0.1 2.1 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFM60646.1 - 0.00077 19.4 0.6 0.00077 19.4 0.6 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFM60646.1 - 0.00084 19.2 3.0 0.0013 18.5 3.0 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain C1_2 PF03107.16 KFM60646.1 - 0.0037 17.5 1.1 2 8.8 0.1 2.3 2 0 0 2 2 2 2 C1 domain ZZ PF00569.17 KFM60646.1 - 0.0038 17.0 0.7 1.1 9.1 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type zf-C2H2_7 PF15269.6 KFM60646.1 - 0.0052 16.8 2.5 0.0052 16.8 2.5 1.8 1 1 0 2 2 2 1 Zinc-finger Zn-ribbon_8 PF09723.10 KFM60646.1 - 0.013 15.6 1.0 0.48 10.6 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 KFM60646.1 - 0.03 14.2 0.8 0.093 12.6 0.1 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-HIT PF04438.16 KFM60646.1 - 0.25 11.3 5.3 2.2 8.2 1.0 2.2 2 0 0 2 2 2 0 HIT zinc finger Desulfoferrod_N PF06397.12 KFM60646.1 - 0.25 11.0 0.1 0.25 11.0 0.1 2.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf_C2H2_ZHX PF18387.1 KFM60646.1 - 0.54 9.9 6.7 3.4 7.4 0.7 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Mss51 PF13824.6 KFM60646.1 - 0.96 9.6 5.7 9.7 6.4 0.4 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_12 PF18658.1 KFM60647.1 - 0.019 14.5 1.7 0.022 14.3 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-C2H2 PF00096.26 KFM60648.1 - 1.3e-09 37.9 5.3 0.00012 22.3 0.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM60648.1 - 1.6e-09 37.8 8.1 0.0013 19.1 0.2 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM60648.1 - 4.6e-06 27.0 5.4 0.0014 19.3 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFM60648.1 - 0.00016 21.9 1.2 0.0002 21.6 1.2 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KFM60648.1 - 0.0017 18.4 0.5 0.29 11.3 0.0 2.2 2 0 0 2 2 2 1 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFM60648.1 - 0.0046 16.9 0.1 0.0046 16.9 0.1 2.5 3 0 0 3 3 3 1 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 KFM60648.1 - 0.0084 16.1 1.2 1.2 9.2 0.0 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zf-P11 PF03854.14 KFM60648.1 - 0.012 15.2 1.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-H2C2_5 PF13909.6 KFM60648.1 - 0.026 14.3 5.7 0.17 11.7 0.6 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain ZZ PF00569.17 KFM60648.1 - 0.032 14.0 1.4 5.7 6.8 0.2 2.4 2 1 0 2 2 2 0 Zinc finger, ZZ type zf-C2H2_7 PF15269.6 KFM60648.1 - 0.05 13.7 2.3 0.05 13.7 2.3 2.0 1 1 1 2 2 2 0 Zinc-finger C1_2 PF03107.16 KFM60648.1 - 0.06 13.7 5.3 1.6 9.1 0.6 2.5 1 1 1 2 2 2 0 C1 domain Actin_micro PF17003.5 KFM60648.1 - 0.063 12.4 1.1 1.4 8.0 0.1 1.9 1 1 1 2 2 2 0 Putative actin-like family Desulfoferrod_N PF06397.12 KFM60648.1 - 0.39 10.4 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-HIT PF04438.16 KFM60648.1 - 0.46 10.4 5.8 4 7.4 1.4 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2_11 PF16622.5 KFM60648.1 - 0.62 9.9 3.9 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type DDE_1 PF03184.19 KFM60649.1 - 1.3e-05 25.0 0.2 1.4e-05 24.8 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CX9C PF16860.5 KFM60650.1 - 1.7e-05 24.7 9.9 0.0095 15.9 0.6 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, PTH2 PF01981.16 KFM60652.1 - 1.4e-40 138.2 0.1 1.9e-40 137.8 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 zf-CSL PF05207.13 KFM60654.1 - 5.5e-25 86.9 1.7 5.5e-25 86.9 1.7 1.4 2 0 0 2 2 2 1 CSL zinc finger zf-RING_7 PF02591.15 KFM60654.1 - 0.062 13.5 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain Rad60-SLD_2 PF13881.6 KFM60655.1 - 2.5e-31 108.0 0.0 2.9e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFM60655.1 - 0.00052 19.7 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFM60655.1 - 0.067 13.8 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SAC3_GANP PF03399.16 KFM60656.1 - 1.1e-59 202.2 0.8 1.3e-59 202.0 0.8 1.0 1 0 0 1 1 1 1 SAC3/GANP family SAC3_GANP PF03399.16 KFM60657.1 - 6.4e-13 48.7 0.1 7e-13 48.6 0.1 1.0 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KFM60657.1 - 0.0065 16.5 0.0 0.0065 16.5 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Peptidase_S49_N PF08496.10 KFM60658.1 - 0.07 13.2 0.9 0.14 12.3 0.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ion_trans PF00520.31 KFM60659.1 - 1.1e-07 31.3 0.9 1.2e-07 31.2 0.9 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM60659.1 - 0.004 15.9 0.3 0.004 15.9 0.3 1.0 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFM60660.1 - 1.2e-13 50.9 2.3 1.3e-13 50.7 0.6 1.7 2 0 0 2 2 2 1 Ion transport protein SARAF PF06682.12 KFM60660.1 - 0.0071 16.0 0.0 0.0076 15.9 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis PKD_channel PF08016.12 KFM60660.1 - 0.041 12.6 0.8 0.048 12.3 0.8 1.1 1 0 0 1 1 1 0 Polycystin cation channel DUF4834 PF16118.5 KFM60660.1 - 0.044 14.8 0.0 0.061 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ctr PF04145.15 KFM60660.1 - 0.048 14.3 0.1 0.06 14.0 0.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF2973 PF11189.8 KFM60660.1 - 0.051 13.7 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) NicO PF03824.16 KFM60660.1 - 0.059 12.7 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein TMEM208_SND2 PF05620.11 KFM60660.1 - 0.064 13.0 0.2 0.095 12.5 0.2 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 TMEM52 PF14979.6 KFM60660.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 TMEM154 PF15102.6 KFM60660.1 - 0.16 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Ion_trans PF00520.31 KFM60665.1 - 3e-27 95.4 5.3 3.6e-27 95.2 5.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KFM60666.1 - 2.5e-10 40.0 1.4 3.1e-10 39.7 1.4 1.1 1 0 0 1 1 1 1 Ion transport protein Shisa PF13908.6 KFM60666.1 - 0.089 13.0 0.6 0.26 11.5 0.1 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator LRR_4 PF12799.7 KFM60668.1 - 3.5e-18 65.4 26.3 2.9e-08 33.9 5.7 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM60668.1 - 1.1e-15 57.2 15.2 1.1e-11 44.3 5.5 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 KFM60668.1 - 3e-06 26.8 5.6 1.3e-05 24.7 4.8 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFM60668.1 - 4.7e-05 23.4 10.2 1.9 9.4 1.2 4.7 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 KFM60668.1 - 9.5e-05 22.2 13.0 1.2 9.4 1.0 4.4 4 0 0 4 4 4 4 Leucine Rich repeat LRR_4 PF12799.7 KFM60669.1 - 0.027 14.9 0.2 0.048 14.1 0.2 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM60669.1 - 0.052 13.3 0.9 0.076 12.8 0.9 1.4 1 0 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.33 KFM60669.1 - 0.81 10.5 3.0 0.81 10.5 0.5 2.4 2 0 0 2 2 2 0 Leucine Rich Repeat DUF5641 PF18701.1 KFM60670.1 - 5.4e-22 77.8 0.2 1.2e-21 76.7 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 KFM60670.1 - 9.4e-10 38.5 1.0 2.7e-09 37.0 1.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM60670.1 - 3.3e-06 27.3 0.0 6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KFM60670.1 - 0.00021 21.5 0.9 0.00048 20.3 0.9 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 KFM60670.1 - 0.032 14.0 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain HTH_Tnp_Tc3_2 PF01498.18 KFM60673.1 - 4.5e-16 58.8 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60673.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60673.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60673.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60673.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Autophagy_N PF03986.13 KFM60675.1 - 0.025 14.5 0.2 0.032 14.2 0.2 1.1 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Med6 PF04934.14 KFM60675.1 - 0.044 13.6 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 MED6 mediator sub complex component protein_MS5 PF04776.12 KFM60675.1 - 0.062 13.4 1.4 1.4 9.0 0.6 2.2 1 1 1 2 2 2 0 Protein MS5 LST1 PF05083.13 KFM60676.1 - 0.014 15.7 0.2 0.018 15.3 0.2 1.2 1 0 0 1 1 1 0 LST-1 protein Herpes_gE PF02480.16 KFM60676.1 - 0.066 12.0 0.0 0.066 12.0 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Peptidase_M13_N PF05649.13 KFM60677.1 - 3.1e-93 313.5 0.1 3.9e-93 313.2 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 DUF2909 PF11137.8 KFM60677.1 - 0.0062 16.4 3.4 2 8.4 1.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2909) zf-CDGSH PF09360.10 KFM60678.1 - 3.8e-10 39.8 0.9 5.3e-10 39.4 0.3 1.7 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type HTH_Tnp_Tc3_2 PF01498.18 KFM60680.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60680.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60680.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60680.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60680.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain wnt PF00110.19 KFM60681.1 - 7.7e-46 157.1 1.9 8.5e-46 157.0 1.9 1.0 1 0 0 1 1 1 1 wnt family IL17 PF06083.11 KFM60682.1 - 1.2e-12 48.1 1.1 3.2e-12 46.7 1.1 1.7 1 0 0 1 1 1 1 Interleukin-17 His_kinase PF06580.13 KFM60682.1 - 0.02 15.2 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase MgtE_N PF03448.17 KFM60683.1 - 0.068 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain HTH_Tnp_Tc3_2 PF01498.18 KFM60684.1 - 2.5e-16 59.7 2.2 4.5e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60684.1 - 4.1e-14 52.6 0.0 6.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Septin PF00735.18 KFM60685.1 - 1.1e-127 425.1 0.1 1.3e-127 424.9 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFM60685.1 - 4.3e-08 33.2 0.0 1.1e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM60685.1 - 1.9e-07 31.2 0.2 1.3e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFM60685.1 - 9.8e-06 25.2 0.0 0.19 11.3 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFM60685.1 - 2.2e-05 23.9 0.2 7.7e-05 22.1 0.0 2.0 3 0 0 3 3 3 1 AIG1 family Dynamin_N PF00350.23 KFM60685.1 - 8.6e-05 22.6 0.4 0.13 12.3 0.0 2.8 2 1 1 3 3 3 2 Dynamin family Ras PF00071.22 KFM60685.1 - 0.00037 20.1 0.4 0.0027 17.3 0.0 2.6 3 1 0 4 4 4 1 Ras family Gtr1_RagA PF04670.12 KFM60685.1 - 0.0027 17.1 0.3 0.082 12.2 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KFM60685.1 - 0.0046 17.2 0.0 0.012 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 KFM60685.1 - 0.0048 17.1 0.0 0.0097 16.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KFM60685.1 - 0.0077 16.8 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KFM60685.1 - 0.0086 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM60685.1 - 0.0094 16.3 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 KFM60685.1 - 0.011 14.9 1.3 3.6 6.7 0.2 2.7 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 KFM60685.1 - 0.023 14.2 0.1 0.056 12.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KFM60685.1 - 0.09 13.3 0.2 0.39 11.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFM60685.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain IIGP PF05049.13 KFM60685.1 - 0.16 11.0 0.6 0.46 9.5 0.0 1.9 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) Phe_ZIP PF08916.11 KFM60686.1 - 7.8e-19 68.1 0.1 1.8e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 Phenylalanine zipper VEFS-Box PF09733.9 KFM60686.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein SH2 PF00017.24 KFM60687.1 - 1.6e-09 37.7 0.0 1.6e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 SH2 domain PseudoU_synth_2 PF00849.22 KFM60688.1 - 3.3e-08 33.8 0.0 4.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase PseudoU_synth_2 PF00849.22 KFM60689.1 - 5.7e-20 72.0 2.2 6.3e-20 71.9 0.1 2.2 2 0 0 2 2 2 1 RNA pseudouridylate synthase Alpha-amylase PF00128.24 KFM60690.1 - 8.6e-86 288.5 0.6 1.2e-85 288.1 0.6 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SNF PF00209.18 KFM60691.1 - 2.9e-14 52.7 0.0 3.1e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DDE_3 PF13358.6 KFM60692.1 - 2.4e-10 40.4 0.0 3.2e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FAM101 PF15068.6 KFM60693.1 - 0.00011 22.3 1.1 0.022 14.7 0.1 2.2 2 0 0 2 2 2 2 FAM101 family Vps53_N PF04100.12 KFM60694.1 - 5.7e-152 506.1 10.1 6.5e-152 505.9 7.9 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 KFM60694.1 - 1e-10 41.4 4.1 3.3e-10 39.7 4.1 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Tropomyosin PF00261.20 KFM60694.1 - 9.9e-05 21.8 1.1 0.00023 20.6 1.1 1.5 1 0 0 1 1 1 1 Tropomyosin VPS53_C PF16854.5 KFM60694.1 - 0.00016 21.6 0.0 0.00016 21.6 0.0 3.4 4 0 0 4 4 4 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps51 PF08700.11 KFM60694.1 - 0.00091 19.3 1.6 0.013 15.5 0.0 3.2 3 0 0 3 3 3 1 Vps51/Vps67 Spc7 PF08317.11 KFM60694.1 - 0.0018 17.2 5.4 0.0034 16.3 5.4 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2451 PF10474.9 KFM60694.1 - 0.0022 17.8 1.2 0.0064 16.3 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) NBD94 PF16830.5 KFM60694.1 - 0.0028 18.0 2.1 0.013 15.9 2.1 2.3 1 0 0 1 1 1 1 Nucleotide-Binding Domain 94 of RH Laminin_II PF06009.12 KFM60694.1 - 0.0046 17.0 4.2 0.017 15.2 4.2 2.0 1 0 0 1 1 1 1 Laminin Domain II PrpF PF04303.13 KFM60694.1 - 0.017 14.1 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 PrpF protein Sec8_exocyst PF04048.14 KFM60694.1 - 0.019 14.8 1.9 0.075 12.9 1.9 2.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain GrpE PF01025.19 KFM60694.1 - 0.023 14.4 5.6 0.061 13.0 3.5 2.5 2 0 0 2 2 2 0 GrpE DUF4446 PF14584.6 KFM60694.1 - 0.027 14.5 2.5 9.3 6.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DUF4441 PF14536.6 KFM60694.1 - 0.11 12.7 2.7 15 5.8 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4441) XhlA PF10779.9 KFM60694.1 - 0.14 12.4 7.1 0.048 13.9 3.2 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Dor1 PF04124.12 KFM60694.1 - 0.21 10.2 4.9 0.33 9.6 3.9 1.7 2 0 0 2 2 2 0 Dor1-like family CREPT PF16566.5 KFM60694.1 - 0.26 11.4 3.3 1.1 9.4 1.6 3.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4337 PF14235.6 KFM60694.1 - 0.46 10.6 3.0 1 9.5 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ING PF12998.7 KFM60694.1 - 1.1 9.9 6.1 1.7 9.3 3.8 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ATG16 PF08614.11 KFM60694.1 - 1.8 8.7 6.5 1.1 9.4 3.0 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KFM60694.1 - 2.2 8.3 10.7 0.62 10.1 3.9 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 KFM60694.1 - 3.6 8.3 6.7 2.2 9.0 2.8 2.6 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2203) Acyl-CoA_dh_1 PF00441.24 KFM60695.1 - 2.7e-36 125.0 6.1 4.7e-36 124.3 6.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM60695.1 - 1.1e-35 122.7 0.0 3.3e-35 121.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM60695.1 - 9.7e-27 93.0 0.0 1.8e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM60695.1 - 1.7e-17 63.9 5.9 2.5e-17 63.4 5.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LSM PF01423.22 KFM60696.1 - 1.8e-11 43.5 0.1 2.3e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF3025 PF11227.8 KFM60697.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) SOCS_box PF07525.16 KFM60698.1 - 1.1e-11 44.9 3.0 1.8e-11 44.2 3.0 1.3 1 0 0 1 1 1 1 SOCS box Transglut_N PF00868.20 KFM60699.1 - 0.00049 20.4 0.1 0.00049 20.4 0.1 1.0 1 0 0 1 1 1 1 Transglutaminase family Anoctamin PF04547.12 KFM60702.1 - 5.8e-13 48.5 0.0 5.8e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Rer1 PF03248.13 KFM60702.1 - 0.024 14.3 0.3 0.049 13.4 0.3 1.4 1 0 0 1 1 1 0 Rer1 family Anoctamin PF04547.12 KFM60703.1 - 2.4e-40 138.8 2.6 2.6e-40 138.6 2.6 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoctamin PF04547.12 KFM60704.1 - 2.7e-26 92.4 0.8 2.9e-26 92.3 0.8 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel HTH_Tnp_Tc3_2 PF01498.18 KFM60705.1 - 5.2e-16 58.7 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60705.1 - 4.7e-14 52.4 0.0 8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60705.1 - 2.3e-07 30.5 0.2 7e-07 28.9 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60705.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60705.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain THAP PF05485.12 KFM60707.1 - 0.00011 23.1 0.3 0.00011 23.0 0.3 1.0 1 0 0 1 1 1 1 THAP domain AP_endonuc_2 PF01261.24 KFM60708.1 - 2.9e-16 59.5 0.0 3.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HTH_Tnp_Tc3_2 PF01498.18 KFM60711.1 - 1.9e-16 60.1 2.2 5e-16 58.7 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60711.1 - 1.1e-13 51.2 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60711.1 - 5.8e-07 29.2 0.5 3.1e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60711.1 - 0.011 15.5 0.3 0.029 14.1 0.3 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM60711.1 - 4.2 8.0 13.0 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM60712.1 - 6e-16 58.5 0.1 6.1e-15 55.3 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60712.1 - 7.9e-15 54.9 5.4 1.4e-14 54.0 5.4 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM60712.1 - 0.0025 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60712.1 - 0.011 16.3 1.4 0.011 16.3 1.4 2.6 2 1 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 KFM60712.1 - 0.018 15.2 0.1 0.067 13.3 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM60712.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix Penicillinase_R PF03965.16 KFM60712.1 - 0.079 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Penicillinase repressor HTH_Tnp_Tc3_2 PF01498.18 KFM60713.1 - 5.1e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60713.1 - 2.2e-13 50.2 0.0 3.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60713.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60713.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60713.1 - 0.03 14.4 0.4 0.091 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM60713.1 - 2.5 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain TLE_N PF03920.15 KFM60714.1 - 1.5e-18 67.1 1.9 1.6e-18 67.1 1.9 1.0 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain Ribosomal_S18 PF01084.20 KFM60714.1 - 0.0047 17.1 0.6 0.0051 17.0 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Phage_Arf PF17585.2 KFM60714.1 - 0.13 12.2 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 Accessory recombination function protein GAGA PF09237.11 KFM60715.1 - 0.001 18.8 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 GAGA factor ING PF12998.7 KFM60716.1 - 2e-18 66.8 4.6 3.3e-18 66.1 4.6 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFM60716.1 - 4.9e-06 26.3 8.1 8e-06 25.7 8.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFM60716.1 - 0.014 15.0 2.3 0.022 14.3 2.3 1.4 1 0 0 1 1 1 0 PHD-finger Myosin_tail_1 PF01576.19 KFM60716.1 - 0.053 11.3 7.9 0.062 11.1 7.9 1.0 1 0 0 1 1 1 0 Myosin tail zf-HC5HC2H PF13771.6 KFM60716.1 - 0.15 12.3 3.6 0.13 12.6 1.7 1.9 2 1 0 2 2 2 0 PHD-like zinc-binding domain TIR_2 PF13676.6 KFM60718.1 - 0.012 16.2 0.1 0.026 15.1 0.1 1.6 1 0 0 1 1 1 0 TIR domain SNAPc19 PF15497.6 KFM60719.1 - 0.0048 17.3 1.9 0.024 15.1 0.7 2.1 2 0 0 2 2 2 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Fez1 PF06818.15 KFM60719.1 - 0.0082 16.6 0.1 0.0097 16.4 0.1 1.1 1 0 0 1 1 1 1 Fez1 RVT_1 PF00078.27 KFM60720.1 - 2.3e-28 99.2 0.7 8.4e-28 97.4 0.2 2.0 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) P22_AR_C PF10548.9 KFM60720.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 P22AR C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM60721.1 - 2.4e-16 59.7 2.2 5.4e-16 58.6 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60721.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60721.1 - 2.7e-06 27.0 0.8 1.2e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60721.1 - 0.0073 16.1 0.3 0.021 14.6 0.3 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM60721.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase HTH_32 PF13565.6 KFM60721.1 - 4.1 8.1 14.7 0.12 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain SpoVIF PF14069.6 KFM60723.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Stage VI sporulation protein F NAD_binding_6 PF08030.12 KFM60724.1 - 5.1e-22 78.7 0.0 5e-21 75.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFM60724.1 - 2.5e-19 69.3 0.0 6.1e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KFM60724.1 - 0.011 16.4 0.0 0.04 14.5 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM60725.1 - 0.006 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Transposase Sirohm_synth_C PF14823.6 KFM60728.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal DcpS_C PF11969.8 KFM60730.1 - 0.03 14.8 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding FlxA PF14282.6 KFM60730.1 - 0.034 14.1 1.3 0.073 13.1 1.0 1.7 1 1 0 1 1 1 0 FlxA-like protein TraI_2 PF07514.11 KFM60730.1 - 0.062 12.2 0.1 0.079 11.9 0.1 1.1 1 0 0 1 1 1 0 Putative helicase DUF3573 PF12097.8 KFM60730.1 - 0.12 11.2 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Ig_3 PF13927.6 KFM60731.1 - 1.2e-34 118.8 4.0 8.4e-14 51.9 0.3 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM60731.1 - 9.5e-32 108.9 0.2 3e-12 46.5 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFM60731.1 - 5.8e-22 77.7 2.1 8.4e-08 32.3 0.3 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM60731.1 - 7.8e-19 67.9 4.2 5.3e-06 26.6 0.1 4.2 3 1 1 4 4 4 3 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM60731.1 - 1.4e-18 66.9 2.4 5.1e-06 26.7 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_5 PF16681.5 KFM60731.1 - 1.9e-07 31.4 0.3 1.8 9.0 0.0 3.6 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM60731.1 - 8.4e-05 22.8 0.8 0.37 11.1 0.0 3.9 3 2 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFM60731.1 - 9.2e-05 21.9 0.0 0.59 9.7 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFM60731.1 - 0.00022 21.2 0.4 0.32 11.1 0.0 3.2 3 1 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM60731.1 - 0.001 19.1 0.1 5.7 7.1 0.0 3.4 3 1 0 3 3 3 2 C17orf99 Ig domain C2-set_2 PF08205.12 KFM60731.1 - 0.0031 17.6 0.3 0.27 11.3 0.0 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C2-set PF05790.15 KFM60731.1 - 0.0036 17.5 0.1 1.8 8.8 0.0 2.9 3 0 0 3 3 2 1 Immunoglobulin C2-set domain C1-set PF07654.15 KFM60731.1 - 0.86 10.0 5.3 3.1 8.2 0.2 3.2 3 1 0 3 3 3 0 Immunoglobulin C1-set domain HTH_Tnp_Tc3_2 PF01498.18 KFM60732.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60732.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM60733.1 - 4.8e-12 45.9 0.0 7.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60733.1 - 4.2e-10 39.7 0.4 8.8e-10 38.7 0.4 1.4 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM60734.1 - 3.5e-16 59.2 3.4 5.4e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60734.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60734.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60734.1 - 0.0024 17.6 0.6 0.0072 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60734.1 - 0.026 14.7 0.4 0.086 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM60734.1 - 2 9.1 15.6 0.12 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM60735.1 - 1.3e-07 31.3 0.1 1.5e-07 31.1 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 CWC25 PF12542.8 KFM60737.1 - 8.5e-08 33.0 0.1 8.5e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing factor I-set PF07679.16 KFM60738.1 - 7.4e-165 535.6 0.0 1.5e-18 66.7 0.0 10.1 10 0 0 10 10 10 9 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM60738.1 - 5.4e-107 350.5 0.0 7.5e-14 52.1 0.0 9.8 9 0 0 9 9 9 9 Immunoglobulin domain Pkinase PF00069.25 KFM60738.1 - 1.8e-96 322.6 0.0 1.1e-48 165.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_2 PF13895.6 KFM60738.1 - 2.5e-60 200.8 0.3 2.6e-07 30.9 0.1 9.8 10 0 0 10 10 9 9 Immunoglobulin domain ig PF00047.25 KFM60738.1 - 1.8e-58 194.7 0.0 3.6e-07 30.3 0.0 9.5 9 0 0 9 9 9 9 Immunoglobulin domain Pkinase_Tyr PF07714.17 KFM60738.1 - 5.8e-49 166.7 0.0 3e-24 85.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase V-set PF07686.17 KFM60738.1 - 8.8e-29 99.9 1.6 0.095 12.9 0.2 12.7 9 5 0 9 9 9 7 Immunoglobulin V-set domain fn3 PF00041.21 KFM60738.1 - 4.2e-26 91.1 0.4 4.6e-14 52.5 0.4 2.8 2 0 0 2 2 2 2 Fibronectin type III domain C2-set_2 PF08205.12 KFM60738.1 - 4.4e-13 49.1 0.2 0.59 10.2 0.0 8.5 9 0 0 9 9 9 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM60738.1 - 6.3e-07 28.9 0.6 0.15 11.7 0.2 5.1 6 0 0 6 6 5 2 Immunoglobulin domain Receptor_2B4 PF11465.8 KFM60738.1 - 1.3e-05 25.4 0.1 1.6 9.0 0.0 5.0 6 0 0 6 6 5 2 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 KFM60738.1 - 6.5e-05 22.9 0.6 4.6 7.3 0.0 5.3 6 0 0 6 6 5 1 C17orf99 Ig domain Tissue_fac PF01108.17 KFM60738.1 - 0.00019 21.2 0.0 0.83 9.5 0.0 2.6 2 0 0 2 2 2 2 Tissue factor Pur_ac_phosph_N PF16656.5 KFM60738.1 - 0.0047 17.5 0.9 0.35 11.5 0.4 3.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Kdo PF06293.14 KFM60738.1 - 0.031 13.6 0.1 0.095 12.0 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family V-set_CD47 PF08204.11 KFM60738.1 - 0.035 14.1 1.0 19 5.2 0.0 4.9 6 0 0 6 6 6 0 CD47 immunoglobulin-like domain TAP35_44 PF07265.11 KFM60738.1 - 0.18 11.8 0.1 0.68 10.0 0.1 1.9 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 I-set PF07679.16 KFM60739.1 - 1.9e-159 518.2 0.4 2e-23 82.2 0.0 8.0 8 0 0 8 8 8 8 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM60739.1 - 7.9e-111 362.9 0.0 6.3e-14 52.3 0.0 8.2 8 0 0 8 8 8 8 Immunoglobulin domain ig PF00047.25 KFM60739.1 - 3.1e-69 229.2 1.1 1.7e-08 34.5 0.1 8.3 8 0 0 8 8 8 8 Immunoglobulin domain Ig_2 PF13895.6 KFM60739.1 - 3.5e-68 225.9 0.6 6.7e-08 32.8 0.1 8.2 8 0 0 8 8 8 8 Immunoglobulin domain V-set PF07686.17 KFM60739.1 - 1.3e-43 147.6 6.9 0.00016 21.8 0.1 10.1 8 3 0 8 8 8 8 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM60739.1 - 2.3e-24 85.3 0.4 0.0089 16.1 0.0 7.9 8 0 0 8 8 8 6 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM60739.1 - 2.6e-15 56.2 1.6 3 8.0 0.0 8.4 8 0 0 8 8 8 3 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFM60739.1 - 7.9e-15 55.0 4.7 0.0098 16.1 0.1 7.6 7 1 1 8 8 8 3 Natural killer cell receptor 2B4 Ig_6 PF18452.1 KFM60739.1 - 1.3e-14 53.4 0.0 0.049 13.2 0.0 6.8 8 0 0 8 8 8 4 Immunoglobulin domain Ig_5 PF16681.5 KFM60739.1 - 4.9e-10 39.7 4.3 8.3 6.9 0.0 8.5 8 1 0 8 8 8 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM60739.1 - 1.6e-09 37.8 6.8 2.2 8.6 0.1 8.5 8 1 0 8 8 8 2 T-cell surface glycoprotein CD3 delta chain BiPBP_C PF06832.12 KFM60739.1 - 2.2e-09 37.2 0.0 0.14 12.2 0.0 6.6 7 0 0 7 7 7 2 Penicillin-Binding Protein C-terminus Family Ig_C17orf99 PF17736.1 KFM60739.1 - 4.3e-08 33.1 0.3 11 6.2 0.0 7.0 7 0 0 7 7 7 1 C17orf99 Ig domain Herpes_gE PF02480.16 KFM60739.1 - 4.4e-07 29.0 1.3 2.8 6.6 0.0 6.5 6 2 0 8 8 8 1 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.11 KFM60739.1 - 1.5e-05 25.0 5.0 1.4 8.9 0.0 6.4 7 0 0 7 7 7 1 CD47 immunoglobulin-like domain ACAS_N PF16177.5 KFM60739.1 - 0.00022 21.1 3.3 12 5.9 0.1 5.1 5 0 0 5 5 5 0 Acetyl-coenzyme A synthetase N-terminus 7tm_2 PF00002.24 KFM60741.1 - 0.00032 20.1 1.0 0.00038 19.8 1.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ig_3 PF13927.6 KFM60742.1 - 7e-13 49.0 0.1 4.7e-06 27.1 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM60742.1 - 1.1e-09 38.2 0.0 1.5e-05 24.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM60742.1 - 2.7e-09 37.2 0.2 0.00047 20.4 0.1 2.9 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFM60742.1 - 2.7e-08 33.9 0.2 0.0019 18.3 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain C1-set PF07654.15 KFM60742.1 - 7.3e-05 23.1 0.1 0.051 13.9 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin C1-set domain C2-set_2 PF08205.12 KFM60742.1 - 0.0033 17.5 0.8 0.53 10.4 0.0 3.0 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain GAIN PF16489.5 KFM60742.1 - 0.03 13.8 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain FGGY_N PF00370.21 KFM60744.1 - 1.4e-42 146.0 0.0 3.1e-41 141.6 0.0 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFM60744.1 - 0.006 16.3 0.2 0.011 15.5 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RVT_1 PF00078.27 KFM60746.1 - 0.004 16.7 0.1 0.011 15.3 0.0 1.6 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1053 PF06327.14 KFM60747.1 - 0.037 14.6 0.2 0.095 13.3 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) DMAP1_like PF17024.5 KFM60747.1 - 0.086 13.0 0.9 0.32 11.1 0.2 2.3 2 1 0 2 2 2 0 Putative DMAP1-like Sec16_C PF12931.7 KFM60747.1 - 0.25 11.0 1.3 0.55 9.8 1.0 1.6 2 1 0 2 2 2 0 Sec23-binding domain of Sec16 Arc_C PF18162.1 KFM60749.1 - 0.00016 21.5 0.4 0.00034 20.4 0.4 1.5 1 0 0 1 1 1 1 Arc C-lobe Retrotrans_gag PF03732.17 KFM60749.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein FAM110_C PF14160.6 KFM60752.1 - 9.4e-20 71.8 1.7 9.4e-20 71.8 1.7 3.1 1 1 1 2 2 2 1 Centrosome-associated C terminus FERM_M PF00373.18 KFM60753.1 - 8.7e-13 48.7 0.1 1.5e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFM60753.1 - 0.00072 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 FERM N-terminal domain PH PF00169.29 KFM60754.1 - 2.3e-33 114.8 0.1 1.1e-18 67.7 0.0 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFM60754.1 - 1.1e-10 41.9 5.8 6.5e-09 36.2 2.2 3.8 3 1 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 KFM60754.1 - 2e-08 34.3 0.3 5.1e-07 29.7 0.1 2.6 2 1 0 2 2 2 1 PH domain PH_8 PF15409.6 KFM60754.1 - 1.6e-07 31.5 0.1 1.1e-06 28.8 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KFM60754.1 - 0.11 12.9 0.1 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Plant pleckstrin homology-like region GFD1 PF17331.2 KFM60755.1 - 0.029 14.5 2.3 0.053 13.7 2.3 1.5 1 0 0 1 1 1 0 GFD1 mRNA transport factor Pellino PF04710.14 KFM60757.1 - 9.6e-175 581.2 0.0 1.1e-174 581.0 0.0 1.0 1 0 0 1 1 1 1 Pellino Prok-RING_4 PF14447.6 KFM60757.1 - 0.057 13.3 5.6 4.6 7.2 2.3 3.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 KFM60757.1 - 0.099 13.0 1.9 4.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 KFM60757.1 - 1 9.3 2.4 21 5.1 0.0 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_5 PF14634.6 KFM60757.1 - 2 8.4 5.6 3.6 7.6 0.1 3.0 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM60757.1 - 2.3 8.2 7.1 16 5.4 1.1 3.5 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DDE_3 PF13358.6 KFM60759.1 - 5.3e-16 58.7 0.1 6e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60759.1 - 7.9e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM60759.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM60759.1 - 0.0026 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM60759.1 - 0.015 15.4 0.1 0.065 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM60759.1 - 0.035 14.1 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Patched PF02460.18 KFM60760.1 - 3.6e-79 266.8 31.2 1.8e-78 264.6 31.3 1.9 1 1 0 1 1 1 1 Patched family NPC1_N PF16414.5 KFM60760.1 - 1.2e-65 221.5 5.6 1.2e-65 221.5 5.6 1.9 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 KFM60760.1 - 3e-56 189.5 25.5 1.9e-53 180.4 9.3 2.8 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KFM60760.1 - 6.1e-05 20.9 9.7 6.1e-05 20.9 9.7 2.1 2 1 0 2 2 2 1 AcrB/AcrD/AcrF family GalKase_gal_bdg PF10509.9 KFM60761.1 - 2.4e-23 81.4 0.0 5.1e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KFM60761.1 - 4.2e-13 49.3 0.9 7.5e-13 48.5 0.9 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFM60762.1 - 5e-15 55.6 0.1 1.1e-14 54.5 0.0 1.6 2 0 0 2 2 2 1 GHMP kinases C terminal Pkinase_Tyr PF07714.17 KFM60763.1 - 1.6e-32 112.8 0.0 2.6e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 KFM60763.1 - 3e-26 91.1 11.8 1.5e-10 41.1 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM60763.1 - 4.1e-21 74.4 3.2 1.5e-05 25.2 0.8 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KFM60763.1 - 1.4e-20 73.7 0.6 3.6e-11 43.5 0.9 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Pkinase PF00069.25 KFM60763.1 - 8.6e-20 71.2 0.0 2e-19 70.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 KFM60763.1 - 8.5e-18 64.5 3.0 1.2e-08 35.3 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM60763.1 - 6e-16 56.9 2.7 6.7e-05 23.0 0.2 4.1 4 0 0 4 4 4 3 Ankyrin repeat Homeodomain PF00046.29 KFM60764.1 - 1.2e-19 69.9 10.0 1.8e-19 69.3 10.0 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM60764.1 - 0.0052 16.6 0.6 0.0052 16.6 0.6 1.7 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_Tc3_2 PF01498.18 KFM60765.1 - 4.1e-16 59.0 3.4 5.2e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60765.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60765.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60765.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60765.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM60768.1 - 3.1e-10 40.2 2.3 4.3e-10 39.7 2.3 1.2 1 0 0 1 1 1 1 Transposase Rav1p_C PF12234.8 KFM60769.1 - 2.3e-05 23.1 0.3 2.3e-05 23.0 0.3 1.0 1 0 0 1 1 1 1 RAVE protein 1 C terminal ANAPC4_WD40 PF12894.7 KFM60770.1 - 2.6e-16 59.7 4.4 0.0001 22.5 0.0 6.2 5 2 0 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM60770.1 - 1.7e-13 50.8 24.4 0.00024 21.8 0.3 7.7 8 1 0 8 8 8 3 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 KFM60770.1 - 0.039 13.2 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1794 PF08768.11 KFM60771.1 - 4.8e-32 111.0 0.1 5.4e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Laminin_B PF00052.18 KFM60772.1 - 2.3e-109 361.0 0.0 1.7e-37 128.4 0.0 3.3 3 0 0 3 3 3 3 Laminin B (Domain IV) Laminin_EGF PF00053.24 KFM60772.1 - 7.3e-55 182.9 205.9 4e-09 36.5 17.2 12.6 12 1 0 12 12 10 10 Laminin EGF domain Ig_3 PF13927.6 KFM60772.1 - 6.2e-27 94.0 5.8 7.4e-14 52.1 1.4 4.3 4 0 0 4 4 4 3 Immunoglobulin domain Ldl_recept_a PF00057.18 KFM60772.1 - 1.8e-26 92.0 52.8 3.9e-12 46.2 14.1 7.0 7 0 0 7 7 5 3 Low-density lipoprotein receptor domain class A I-set PF07679.16 KFM60772.1 - 9.8e-23 80.0 0.0 1.6e-13 50.5 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFM60772.1 - 8.4e-21 73.9 0.1 2e-07 31.1 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM60772.1 - 5e-18 65.2 1.6 6.1e-06 26.5 0.1 4.5 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFM60772.1 - 9.2e-15 54.8 0.1 0.0028 17.8 0.0 5.5 4 2 1 5 5 5 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM60772.1 - 0.00014 21.3 0.0 0.11 12.1 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFM60772.1 - 0.0023 18.0 0.0 2.1 8.5 0.0 3.7 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFM60772.1 - 0.0078 16.3 2.2 0.012 15.7 0.8 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ldl_recept_a PF00057.18 KFM60773.1 - 5.9e-174 564.0 336.9 6.2e-13 48.7 7.4 18.1 18 0 0 18 18 18 18 Low-density lipoprotein receptor domain class A SEA PF01390.20 KFM60773.1 - 3.5e-07 30.3 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 SEA domain Carboxyl_trans PF01039.22 KFM60774.1 - 4.5e-91 305.9 0.0 5.2e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KFM60774.1 - 0.055 13.0 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) PseudoU_synth_1 PF01416.20 KFM60775.1 - 5.2e-23 81.6 0.0 8.3e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase EF-hand_1 PF00036.32 KFM60776.1 - 1.3e-08 33.8 0.5 1.5e-08 33.6 0.5 1.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFM60776.1 - 6.3e-08 31.9 0.2 7.2e-08 31.8 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFM60776.1 - 8.5e-06 26.1 0.2 9e-06 26.1 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM60776.1 - 1.7e-05 24.1 0.2 2.8e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KFM60776.1 - 0.00054 19.7 0.1 0.00058 19.6 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.6 KFM60776.1 - 0.069 13.0 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 EF hand EF-hand_13 PF17958.1 KFM60776.1 - 0.12 12.2 0.0 0.13 12.0 0.0 1.0 1 0 0 1 1 1 0 EF-hand domain Ank_2 PF12796.7 KFM60778.1 - 3.2e-63 210.3 1.3 9.2e-15 55.0 0.0 6.5 6 1 1 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM60778.1 - 1.8e-62 206.9 13.8 1e-07 32.4 0.0 11.9 8 4 4 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 KFM60778.1 - 1.7e-53 176.8 13.2 2.4e-07 30.9 0.0 14.4 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 KFM60778.1 - 1.1e-42 143.5 1.7 1.1e-07 31.9 0.0 9.0 7 2 3 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM60778.1 - 3.1e-41 134.6 15.2 0.00058 20.1 0.0 14.5 15 0 0 15 15 15 8 Ankyrin repeat DUF3885 PF13021.6 KFM60778.1 - 0.05 13.7 0.4 5.3 7.2 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) DUF249 PF03158.13 KFM60778.1 - 0.094 12.4 0.1 0.98 9.1 0.0 2.6 3 0 0 3 3 3 0 Multigene family 530 protein PhoU PF01895.19 KFM60778.1 - 0.37 11.3 4.3 0.99 9.9 0.1 3.5 4 0 0 4 4 4 0 PhoU domain Trypsin PF00089.26 KFM60779.1 - 1.7e-59 201.3 0.0 2.3e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM60779.1 - 0.0038 18.1 0.2 0.0087 17.0 0.2 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFM60780.1 - 4.3e-54 183.6 0.0 7e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM60780.1 - 0.0009 20.2 0.0 0.0018 19.2 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KFM60780.1 - 0.0041 16.7 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 DDE_3 PF13358.6 KFM60781.1 - 3.1e-12 46.5 0.0 6.4e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60781.1 - 2.1e-11 43.9 0.1 3.3e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Transposase RNase_H PF00075.24 KFM60782.1 - 5.9e-08 33.0 0.1 9.3e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 RNase H DDE_3 PF13358.6 KFM60783.1 - 0.00049 19.9 0.0 0.0009 19.0 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DRIM PF07539.12 KFM60783.1 - 0.059 11.7 0.0 0.076 11.3 0.0 1.2 1 0 0 1 1 1 0 Down-regulated in metastasis Pkinase PF00069.25 KFM60785.1 - 4e-62 210.0 0.0 1.2e-61 208.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain HR1 PF02185.16 KFM60785.1 - 1.3e-44 150.1 40.5 5.2e-17 61.7 7.5 3.8 3 1 1 4 4 4 3 Hr1 repeat Pkinase_Tyr PF07714.17 KFM60785.1 - 8.3e-40 136.7 0.0 1.6e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Uds1 PF15456.6 KFM60785.1 - 1.3e-07 31.8 18.3 0.0038 17.4 2.0 3.5 3 0 0 3 3 3 3 Up-regulated During Septation Kinase-like PF14531.6 KFM60785.1 - 4.1e-07 29.6 0.0 2.2e-06 27.2 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KFM60785.1 - 0.018 14.0 0.0 0.018 14.0 0.0 3.1 3 1 0 3 3 3 0 Haspin like kinase domain C2 PF00168.30 KFM60785.1 - 0.098 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 C2 domain PTPlike_phytase PF14566.6 KFM60785.1 - 2 8.5 10.4 0.084 13.0 0.5 3.1 4 0 0 4 4 4 0 Inositol hexakisphosphate HTH_Tnp_Tc3_2 PF01498.18 KFM60786.1 - 5.1e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60786.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60786.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60786.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60786.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain OTU PF02338.19 KFM60787.1 - 0.0024 18.3 0.0 0.0096 16.4 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Bromo_TP PF07524.13 KFM60789.1 - 4.6e-16 58.6 0.0 7.5e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 KFM60789.1 - 3.8e-11 42.7 6.2 8.6e-11 41.6 6.2 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFM60789.1 - 0.0067 16.0 4.9 0.0067 16.0 4.9 2.2 2 0 0 2 2 2 1 PHD-finger Bromo_TP_like PF17027.5 KFM60789.1 - 0.0073 16.5 0.3 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 Histone-fold protein NTP_transferase PF00483.23 KFM60790.1 - 4.9e-16 59.1 0.1 1.1e-15 58.0 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KFM60790.1 - 2.4e-10 41.0 0.0 3.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KFM60790.1 - 4.7e-08 32.4 5.5 0.0012 18.5 0.2 3.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KFM60790.1 - 1.2e-06 27.0 4.4 2e-06 26.3 4.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 KFM60790.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.12 KFM60790.1 - 0.00016 20.7 5.7 0.00043 19.3 5.7 1.8 1 1 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 KFM60790.1 - 1.5 8.6 11.7 17 5.2 0.0 3.6 2 2 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 KFM60791.1 - 0.00014 21.3 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM60791.1 - 0.039 13.2 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Homeodomain PF00046.29 KFM60794.1 - 1.3e-05 25.0 4.5 2.3e-05 24.2 4.5 1.4 1 0 0 1 1 1 1 Homeodomain TFIIF_beta PF02270.15 KFM60794.1 - 0.002 18.2 0.1 0.003 17.6 0.1 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain PIF1 PF05970.14 KFM60795.1 - 9.7e-40 136.8 0.1 1.1e-38 133.4 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase EF-G-binding_N PF07299.11 KFM60795.1 - 0.021 15.3 0.8 11 6.6 0.2 2.8 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal AAA_30 PF13604.6 KFM60795.1 - 0.083 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain GspL_C PF12693.7 KFM60795.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 GspL periplasmic domain Bunya_NS-S PF01104.17 KFM60795.1 - 0.15 11.9 0.1 26 4.7 0.0 2.4 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s DUF3913 PF13052.6 KFM60796.1 - 0.0025 18.1 0.0 0.0045 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3913) RT_RNaseH_2 PF17919.1 KFM60797.1 - 9.4e-31 105.8 0.0 4.8e-30 103.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM60797.1 - 2.8e-29 101.5 0.0 1.4e-28 99.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM60797.1 - 1.9e-28 99.5 0.1 5.6e-28 98.0 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM60797.1 - 2.1e-18 66.6 0.0 3.6e-17 62.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM60797.1 - 2.2e-16 59.7 0.6 7.7e-16 57.9 0.0 2.3 2 1 0 2 2 2 1 Integrase zinc binding domain Arc_C PF18162.1 KFM60797.1 - 3.8e-05 23.5 1.7 0.00013 21.7 0.4 2.6 3 0 0 3 3 3 1 Arc C-lobe zf-H2C2 PF09337.10 KFM60797.1 - 0.0017 18.5 0.0 0.004 17.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM60797.1 - 0.022 15.0 0.1 0.23 11.8 0.0 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein 7tm_2 PF00002.24 KFM60798.1 - 0.0017 17.7 1.5 0.0023 17.2 1.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.24 KFM60799.1 - 5.5e-13 48.8 2.6 5.9e-13 48.7 2.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFM60800.1 - 0.00062 20.0 2.8 0.0012 19.1 2.8 1.5 1 0 0 1 1 1 1 Hormone receptor domain Z1 PF10593.9 KFM60801.1 - 0.057 12.9 0.0 0.058 12.9 0.0 1.0 1 0 0 1 1 1 0 Z1 domain DDE_1 PF03184.19 KFM60802.1 - 7.4e-37 126.7 0.1 1.2e-36 126.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ErmC PF06308.11 KFM60802.1 - 0.024 15.0 0.2 0.047 14.0 0.2 1.4 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) AcetylCoA_hydro PF02550.15 KFM60802.1 - 0.089 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain Ada3 PF10198.9 KFM60802.1 - 0.11 12.6 3.4 0.12 12.6 0.3 2.4 2 1 1 3 3 3 0 Histone acetyltransferases subunit 3 HTH_Tnp_Tc3_2 PF01498.18 KFM60804.1 - 3.9e-16 59.0 3.0 6.4e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM60804.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60804.1 - 3.1e-07 30.0 1.6 7.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60804.1 - 0.003 17.3 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60804.1 - 2.9 8.6 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM60805.1 - 2.6e-16 59.6 2.2 4.7e-16 58.8 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60805.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Sugar_tr PF00083.24 KFM60807.1 - 8.9e-11 41.3 5.7 9.5e-11 41.2 5.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM60807.1 - 4.4e-09 35.7 8.7 4.4e-09 35.7 8.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM60808.1 - 6.5e-12 45.0 13.7 1.7e-10 40.4 13.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM60808.1 - 1.1e-07 31.2 15.0 6.3e-05 22.1 8.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Rhomboid PF01694.22 KFM60808.1 - 0.0084 16.1 5.5 0.0096 15.9 3.6 2.1 1 1 0 1 1 1 1 Rhomboid family SKICH PF17751.1 KFM60809.1 - 2.3e-16 60.2 3.1 3.8e-15 56.3 0.7 2.9 2 1 0 2 2 2 1 SKICH domain Exo_endo_phos PF03372.23 KFM60809.1 - 1e-06 28.4 0.0 1.6e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_Tnp_Tc3_2 PF01498.18 KFM60810.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60810.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease TUDOR PF00567.24 KFM60811.1 - 0.0079 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Tudor domain HTH_Tnp_Tc3_2 PF01498.18 KFM60812.1 - 2.3e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60812.1 - 9.8e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60813.1 - 2.1e-06 27.9 0.3 4.1e-06 27.0 0.3 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60814.1 - 3.3e-16 59.4 0.1 3.4e-15 56.1 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60814.1 - 1.4e-10 41.3 1.0 2.9e-10 40.2 1.0 1.6 1 0 0 1 1 1 1 Transposase LSM PF01423.22 KFM60815.1 - 1.6e-16 59.8 0.2 1.9e-16 59.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain MRP-S34 PF16053.5 KFM60816.1 - 3.5e-29 101.0 0.0 4.6e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 MOLO1 PF17175.4 KFM60817.1 - 1.9e-17 63.5 0.0 7e-17 61.7 0.0 1.9 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 KFM60817.1 - 1.8e-05 24.9 0.0 5.7e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 TPM domain SID-1_RNA_chan PF13965.6 KFM60817.1 - 0.072 11.5 0.1 0.098 11.1 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2700 PF10912.8 KFM60817.1 - 0.083 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) Rax2 PF12768.7 KFM60817.1 - 0.088 12.2 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Neurensin PF14927.6 KFM60817.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Neurensin DUF4114 PF13448.6 KFM60817.1 - 0.37 11.6 2.9 1.5e+02 3.3 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4114) Nop PF01798.18 KFM60818.1 - 4.1e-82 275.1 0.0 6.5e-82 274.4 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KFM60818.1 - 2e-48 164.3 1.1 4.2e-48 163.2 1.1 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain RPT PF13446.6 KFM60818.1 - 0.034 14.1 2.8 3.2 7.8 0.3 3.2 2 1 1 3 3 3 0 A repeated domain in UCH-protein DDE_3 PF13358.6 KFM60819.1 - 2.5e-13 50.0 0.0 3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM60820.1 - 2.6e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60820.1 - 3.5e-13 49.6 0.0 6.1e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5641 PF18701.1 KFM60821.1 - 1.5e-18 66.8 0.0 2.2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Exo_endo_phos_2 PF14529.6 KFM60822.1 - 4.7e-18 65.2 0.6 1.3e-17 63.7 0.6 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM60822.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Calpain_III PF01067.22 KFM60824.1 - 1.1e-26 93.8 0.2 1.2e-26 93.6 0.2 1.0 1 0 0 1 1 1 1 Calpain large subunit, domain III AAA_2 PF07724.14 KFM60826.1 - 1.3e-45 155.6 0.1 3.1e-45 154.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_4 PF13637.6 KFM60826.1 - 1.3e-16 60.8 0.0 1.1e-08 35.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM60826.1 - 6.6e-16 58.7 0.8 6.3e-08 33.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM60826.1 - 2.7e-13 48.8 0.0 6.2e-05 23.1 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFM60826.1 - 4.4e-12 45.9 0.2 0.00037 20.8 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFM60826.1 - 5.4e-11 42.5 0.1 0.00035 20.8 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) ClpB_D2-small PF10431.9 KFM60826.1 - 9.4e-11 41.6 2.0 1.7e-10 40.8 0.1 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KFM60826.1 - 3.1e-10 40.2 0.0 2.4e-09 37.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KFM60826.1 - 1.7e-09 38.2 0.1 2.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM60826.1 - 8.6e-07 28.8 0.1 4e-06 26.7 0.0 2.1 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 KFM60826.1 - 2.2e-05 24.9 0.5 0.0022 18.4 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain Zeta_toxin PF06414.12 KFM60826.1 - 6.4e-05 22.3 0.0 0.00023 20.5 0.0 2.0 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KFM60826.1 - 0.00059 20.1 0.3 0.006 16.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KFM60826.1 - 0.0047 16.8 0.0 0.046 13.6 0.0 2.4 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 KFM60826.1 - 0.0056 16.8 0.0 0.021 14.9 0.0 2.0 1 0 0 1 1 1 1 Torsin AAA_14 PF13173.6 KFM60826.1 - 0.0081 16.2 0.0 0.04 13.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFM60826.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFM60826.1 - 0.029 14.3 2.6 0.21 11.5 0.0 3.0 1 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KFM60826.1 - 0.052 13.7 0.5 0.13 12.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KFM60826.1 - 0.095 12.2 0.0 0.43 10.1 0.0 2.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KFM60826.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 KFM60826.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 KFM60826.1 - 0.11 11.8 0.1 3 7.2 0.1 2.3 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KFM60826.1 - 0.15 12.6 0.2 0.56 10.7 0.1 2.2 2 1 0 2 2 1 0 ABC transporter RNA_helicase PF00910.22 KFM60826.1 - 0.23 11.9 0.8 0.81 10.1 0.0 2.4 3 0 0 3 3 1 0 RNA helicase IP_trans PF02121.18 KFM60827.1 - 1.4e-46 159.1 0.1 1.5e-46 159.0 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein IP_trans PF02121.18 KFM60828.1 - 1.2e-67 228.1 0.7 1.3e-67 227.9 0.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein IRK_C PF17655.1 KFM60829.1 - 4.7e-69 231.5 0.0 6.5e-69 231.0 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFM60829.1 - 8.4e-60 200.7 1.8 1.2e-59 200.2 1.8 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFM60829.1 - 0.019 14.9 2.4 0.039 13.9 2.4 1.6 1 1 0 1 1 1 0 Ion channel FAD_binding_7 PF03441.14 KFM60830.1 - 1.4e-72 243.4 0.1 1.6e-72 243.2 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFM60831.1 - 2.6e-31 108.8 0.0 4.5e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase zf-C2H2_4 PF13894.6 KFM60832.1 - 0.00012 22.7 15.9 0.048 14.5 1.2 4.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM60832.1 - 0.00012 22.3 15.2 0.018 15.5 1.0 4.4 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM60832.1 - 0.076 13.0 15.0 0.74 9.9 1.2 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KFM60832.1 - 0.28 11.6 6.9 1.9 9.0 0.3 3.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type A2L_zn_ribbon PF08792.10 KFM60833.1 - 0.061 13.1 1.5 2.4 8.0 1.6 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain fn3 PF00041.21 KFM60834.1 - 8.7e-100 327.2 44.3 1.3e-17 63.9 2.4 8.2 8 0 0 8 8 8 7 Fibronectin type III domain Y_phosphatase PF00102.27 KFM60834.1 - 5.2e-75 252.0 0.7 1e-74 251.1 0.1 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Pur_ac_phosph_N PF16656.5 KFM60834.1 - 1.5e-24 86.4 40.1 6e-05 23.5 0.2 8.8 7 1 0 8 8 8 6 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFM60834.1 - 7e-18 64.6 11.6 0.0054 16.9 0.0 8.0 7 1 0 7 7 7 4 Fibronectin type III domain Interfer-bind PF09294.10 KFM60834.1 - 7e-14 52.0 0.4 0.51 10.7 0.3 7.0 7 0 0 7 7 7 4 Interferon-alpha/beta receptor, fibronectin type III Reeler PF02014.16 KFM60834.1 - 0.00069 20.4 4.6 0.015 16.0 0.1 3.7 3 0 0 3 3 3 1 Reeler domain DSPc PF00782.20 KFM60834.1 - 0.0029 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM60834.1 - 0.003 17.6 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM60834.1 - 0.031 14.4 0.0 0.099 12.8 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF5001 PF16392.5 KFM60834.1 - 0.081 12.8 0.3 0.37 10.7 0.3 2.2 1 0 0 1 1 1 0 Ig-like domain fn3 PF00041.21 KFM60835.1 - 1.6e-25 89.2 1.9 7.6e-14 51.8 0.5 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM60835.1 - 1.5e-09 38.3 3.9 0.00031 21.2 0.9 3.2 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain DUF5001 PF16392.5 KFM60835.1 - 6.9e-05 22.7 0.1 0.0011 18.8 0.3 2.7 2 1 1 3 3 3 1 Ig-like domain fn3_2 PF16893.5 KFM60835.1 - 0.0003 20.9 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.17 KFM60835.1 - 0.0012 18.7 0.3 0.0012 18.7 0.3 1.9 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.10 KFM60835.1 - 0.013 15.8 0.1 0.45 10.8 0.1 2.4 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III CutC PF03932.14 KFM60836.1 - 3e-44 150.9 0.0 3.3e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 CutC family PIF1 PF05970.14 KFM60838.1 - 0.046 12.9 0.7 0.053 12.7 0.7 1.1 1 0 0 1 1 1 0 PIF1-like helicase Rad21_Rec8 PF04824.16 KFM60840.1 - 0.0037 16.5 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF1456 PF07308.13 KFM60840.1 - 0.032 14.6 0.2 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Ank_2 PF12796.7 KFM60842.1 - 4.6e-40 136.1 1.1 3.9e-16 59.4 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM60842.1 - 2.2e-30 104.6 3.3 6.7e-14 52.1 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFM60842.1 - 5e-22 77.3 0.4 5e-07 29.9 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFM60842.1 - 1.6e-21 76.0 0.6 1.1e-09 38.4 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM60842.1 - 2.2e-20 70.5 0.1 1.4e-05 25.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat HTH_Tnp_Tc3_2 PF01498.18 KFM60843.1 - 2.3e-16 59.8 2.2 6.5e-16 58.3 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM60843.1 - 1.5e-13 50.7 0.0 2.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM60843.1 - 3.3e-07 29.9 1.6 7.9e-07 28.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM60843.1 - 0.0031 17.3 0.6 0.0085 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM60843.1 - 2.9 8.6 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain VMA21 PF09446.10 KFM60844.1 - 1e-16 60.8 11.3 1.2e-16 60.5 11.3 1.0 1 0 0 1 1 1 1 VMA21-like domain AA_permease_C PF13906.6 KFM60844.1 - 0.73 9.9 7.2 3 8.0 0.5 2.2 2 0 0 2 2 2 0 C-terminus of AA_permease S1FA PF04689.13 KFM60844.1 - 9.6 6.4 6.8 12 6.1 1.8 2.3 1 1 1 2 2 2 0 DNA binding protein S1FA SH2 PF00017.24 KFM60846.1 - 3.9e-15 55.7 0.0 1.5e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 SH2 domain RNase_T PF00929.24 KFM60848.1 - 7e-10 39.7 0.0 5.6e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 Exonuclease RNase_H_2 PF13482.6 KFM60848.1 - 5.1e-05 23.3 0.3 0.013 15.5 0.0 3.2 3 0 0 3 3 3 1 RNase_H superfamily Spo12 PF05032.12 KFM60848.1 - 0.097 12.6 2.1 0.29 11.1 2.1 1.7 1 0 0 1 1 1 0 Spo12 family SF-assemblin PF06705.11 KFM60848.1 - 0.099 12.0 4.5 0.44 9.8 3.3 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF4371 PF14291.6 KFM60849.1 - 0.01 15.5 0.0 0.01 15.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) DUF4250 PF14056.6 KFM60850.1 - 0.1 12.5 0.6 2.7 8.0 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) HTH_DeoR PF08220.12 KFM60850.1 - 0.13 12.0 0.1 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain CBFD_NFYB_HMF PF00808.23 KFM60851.1 - 6e-21 74.5 0.5 1e-20 73.8 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KFM60851.1 - 5.6e-06 26.5 0.2 1.1e-05 25.5 0.2 1.4 1 0 0 1 1 1 1 CENP-W protein Histone PF00125.24 KFM60851.1 - 3.1e-05 24.3 0.7 5.9e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 AAA_32 PF13654.6 KFM60851.1 - 0.003 16.4 0.2 0.0047 15.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain Frigida PF07899.11 KFM60851.1 - 0.0098 15.2 0.1 0.012 14.9 0.1 1.1 1 0 0 1 1 1 1 Frigida-like protein MSP1_C PF07462.11 KFM60851.1 - 0.086 11.5 0.1 0.096 11.4 0.1 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Matrix PF00661.21 KFM60851.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Viral matrix protein TFIID_20kDa PF03847.13 KFM60851.1 - 0.16 12.5 0.4 0.36 11.3 0.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Plexin_cytopl PF08337.12 KFM60857.1 - 4e-238 791.6 5.2 4.7e-238 791.4 5.2 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFM60858.1 - 4.1e-35 119.7 8.1 3.6e-09 36.6 0.0 5.7 5 0 0 5 5 5 4 IPT/TIG domain TIG_2 PF18020.1 KFM60858.1 - 2.6e-25 88.8 0.0 2.5e-22 79.3 0.0 3.3 3 0 0 3 3 3 1 TIG domain found in plexin TIG_plexin PF17960.1 KFM60858.1 - 8.4e-24 83.4 3.8 6.5e-21 74.1 0.1 4.0 4 0 0 4 4 4 2 TIG domain PSI PF01437.25 KFM60858.1 - 1.4e-21 76.7 50.5 4.5e-10 39.9 11.0 3.6 3 0 0 3 3 3 3 Plexin repeat Sema PF01403.19 KFM60858.1 - 2.1e-09 36.7 0.0 3.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Sema domain Plexin_cytopl PF08337.12 KFM60858.1 - 2.5e-05 23.2 0.0 3.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain CBM60 PF16841.5 KFM60858.1 - 0.0026 18.1 0.0 1.3 9.5 0.0 3.5 3 0 0 3 3 3 1 Ca-dependent carbohydrate-binding module xylan-binding EphA2_TM PF14575.6 KFM60858.1 - 0.044 14.7 0.1 0.1 13.5 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain 60KD_IMP PF02096.20 KFM60858.1 - 0.056 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Syndecan PF01034.20 KFM60858.1 - 0.057 13.4 0.4 0.11 12.4 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain PSI_integrin PF17205.3 KFM60858.1 - 0.91 9.3 48.6 0.22 11.3 10.1 3.7 3 0 0 3 3 3 0 Integrin plexin domain PXA PF02194.15 KFM60860.1 - 2e-44 151.8 2.1 2e-44 151.8 2.1 3.0 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 KFM60860.1 - 2e-26 92.8 0.2 1.3e-24 86.9 0.0 3.3 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 KFM60860.1 - 1.6e-15 57.0 1.2 6.4e-15 55.1 0.1 2.5 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KFM60860.1 - 8.7e-14 51.8 0.5 8.7e-14 51.8 0.5 2.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain FixH PF05751.11 KFM60860.1 - 0.022 14.8 0.9 0.039 14.0 0.1 1.8 2 0 0 2 2 2 0 FixH NtA PF03146.15 KFM60861.1 - 1.4e-14 53.9 0.0 1.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Agrin NtA domain Inj_translocase PF16928.5 KFM60861.1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Cpn60_TCP1 PF00118.24 KFM60867.1 - 7.4e-154 513.0 12.6 8.4e-154 512.8 12.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.21 KFM60867.1 - 0.24 11.5 0.9 0.88 9.7 0.3 2.2 2 0 0 2 2 2 0 Resolvase, N terminal domain PEP-utilizers PF00391.23 KFM60870.1 - 9.6e-21 73.3 0.0 1.5e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Lys PF00062.20 KFM60871.1 - 1.1e-23 83.8 4.0 1.3e-23 83.6 4.0 1.1 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.20 KFM60871.1 - 0.092 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain PEP-utilizers PF00391.23 KFM60872.1 - 8.1e-21 73.5 0.0 1.5e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain ABC_membrane_2 PF06472.15 KFM60872.1 - 0.012 15.0 0.2 0.025 14.0 0.0 1.5 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 PPDK_N PF01326.19 KFM60873.1 - 1.2e-53 182.5 0.0 1.4e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Ribonuclease_P PF00825.18 KFM60875.1 - 0.06 13.4 0.0 4.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease P PEP-utilizers PF00391.23 KFM60876.1 - 2.3e-12 46.5 0.0 4.3e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PPDK_N PF01326.19 KFM60877.1 - 3.1e-45 154.9 0.0 8.3e-45 153.5 0.0 1.6 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PgdA_N PF18627.1 KFM60878.1 - 0.01 15.5 0.1 0.011 15.4 0.1 1.0 1 0 0 1 1 1 0 Peptidoglycan GlcNAc deacetylase N-terminal domain P16-Arc PF04699.14 KFM60878.1 - 0.062 13.8 0.5 0.091 13.2 0.5 1.3 1 1 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Pkinase PF00069.25 KFM60879.1 - 7.3e-46 156.7 0.0 1.4e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM60879.1 - 9.4e-41 139.8 0.0 1.3e-39 136.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Death PF00531.22 KFM60879.1 - 2.4e-08 34.0 0.1 4.9e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Death domain Kinase-like PF14531.6 KFM60879.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-RING_2 PF13639.6 KFM60881.1 - 0.0025 18.1 7.3 0.0095 16.3 7.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFM60881.1 - 0.023 14.6 6.5 0.071 13.0 6.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM60881.1 - 0.029 14.2 8.7 0.037 13.9 6.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM60881.1 - 1 9.4 7.6 2.5 8.1 7.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM60881.1 - 3 7.9 7.4 1.4 9.0 4.0 2.3 2 1 0 2 2 2 0 RING-type zinc-finger IBR PF01485.21 KFM60882.1 - 1.4e-21 76.5 18.0 4.7e-14 52.3 5.1 2.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KFM60882.1 - 0.0092 15.9 8.7 0.0092 15.9 8.7 3.3 3 0 0 3 3 3 1 zinc-RING finger domain Ribonuc_red_sm PF00268.21 KFM60883.1 - 1.3e-122 408.6 3.3 2e-122 408.0 3.3 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 KFM60883.1 - 0.021 14.6 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain TatD_DNase PF01026.21 KFM60884.1 - 2.4e-46 158.2 0.0 2.8e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Beta_elim_lyase PF01212.21 KFM60885.1 - 4.8e-91 305.1 0.1 6e-91 304.7 0.1 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFM60885.1 - 8.2e-12 45.0 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFM60885.1 - 6.2e-05 22.1 0.0 8.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFM60885.1 - 0.00016 21.1 0.1 0.009 15.4 0.1 2.3 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFM60885.1 - 0.0075 14.8 0.0 0.024 13.2 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF22 PF01629.16 KFM60885.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF22 Beta_elim_lyase PF01212.21 KFM60886.1 - 1.1e-11 44.6 0.1 1.1e-11 44.6 0.1 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase DUF22 PF01629.16 KFM60886.1 - 0.074 12.8 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF22 Beta_elim_lyase PF01212.21 KFM60887.1 - 4.2e-66 223.2 0.1 5.3e-66 222.9 0.1 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFM60887.1 - 1.6e-05 24.0 0.0 2.8e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V PPDK_N PF01326.19 KFM60889.1 - 1.8e-64 218.1 0.0 3.1e-64 217.3 0.0 1.4 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Lipoprotein_X PF03305.13 KFM60889.1 - 0.027 14.2 0.3 19 5.0 0.0 3.3 3 0 0 3 3 3 0 Mycoplasma MG185/MG260 protein GalKase_gal_bdg PF10509.9 KFM60890.1 - 0.064 12.8 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KFM60891.1 - 3.7e-15 55.9 0.0 1.6e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFM60891.1 - 6.6e-07 29.6 0.1 1.8e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal Pkinase PF00069.25 KFM60892.1 - 0.00016 21.1 0.0 0.0059 16.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain CD36 PF01130.21 KFM60893.1 - 5.7e-140 466.9 1.1 7.1e-140 466.6 1.1 1.0 1 0 0 1 1 1 1 CD36 family DUF1356 PF07092.12 KFM60893.1 - 0.16 11.2 0.8 15 4.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) RPA43_OB PF17875.1 KFM60895.1 - 0.0061 17.2 0.0 0.0061 17.2 0.0 5.0 4 1 0 4 4 4 1 RPA43 OB domain in RNA Pol I Sushi PF00084.20 KFM60896.1 - 1.3e-25 89.7 16.4 2.3e-10 40.9 2.0 4.4 4 0 0 4 4 4 3 Sushi repeat (SCR repeat) CBM_14 PF01607.24 KFM60896.1 - 0.081 13.1 2.8 5.7 7.2 0.1 2.9 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Insulin_TMD PF17870.1 KFM60896.1 - 0.11 12.5 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DDE_3 PF13358.6 KFM60898.1 - 6.1e-06 26.1 0.0 9.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease tRNA-synt_2b PF00587.25 KFM60899.1 - 1e-25 90.8 0.0 1.5e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pox_VLTF3 PF04947.14 KFM60899.1 - 0.028 14.2 0.1 0.067 12.9 0.1 1.6 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like tRNA-synt_2d PF01409.20 KFM60899.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Exo_endo_phos PF03372.23 KFM60900.1 - 2.1e-05 24.1 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DNA_pol_B_2 PF03175.13 KFM60901.1 - 8.5e-17 61.2 2.5 1.2e-16 60.7 2.5 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Endonuclease_7 PF02945.15 KFM60901.1 - 0.0022 17.9 0.7 0.0044 16.9 0.7 1.4 1 0 0 1 1 1 1 Recombination endonuclease VII CTU2 PF10288.9 KFM60901.1 - 0.033 14.4 0.2 0.057 13.7 0.2 1.3 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Lipase PF00151.19 KFM60902.1 - 5.1e-31 108.2 0.3 3.7e-24 85.6 0.0 2.2 2 0 0 2 2 2 2 Lipase RVT_1 PF00078.27 KFM60902.1 - 7.8e-06 25.6 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF992 PF06186.11 KFM60902.1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF992) Lipase PF00151.19 KFM60904.1 - 2.9e-84 283.3 0.0 1.6e-82 277.5 0.0 2.0 1 1 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFM60904.1 - 3.3e-07 31.1 0.0 4.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KFM60904.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.12 KFM60904.1 - 0.029 13.9 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.8 KFM60904.1 - 0.058 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KFM60904.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KFM60904.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 KFM60904.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.12 KFM60904.1 - 0.23 11.1 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase rRNA_processing PF08524.11 KFM60906.1 - 0.0015 18.6 29.3 0.0024 17.9 29.3 1.3 1 1 0 1 1 1 1 rRNA processing DUF641 PF04859.12 KFM60906.1 - 0.014 15.7 10.4 0.018 15.4 10.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) MCD_N PF17408.2 KFM60906.1 - 1.4 9.1 6.0 0.78 9.9 3.0 2.0 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain CBM_14 PF01607.24 KFM60908.1 - 0.27 11.4 4.7 0.5 10.6 4.7 1.5 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain MFS_1 PF07690.16 KFM60909.1 - 1.6e-46 158.9 42.1 4.3e-45 154.2 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM60909.1 - 0.0056 15.6 34.9 0.034 13.0 12.0 3.9 2 2 1 3 3 3 2 Sugar (and other) transporter UCR_6-4kD PF08997.10 KFM60909.1 - 0.055 13.4 0.0 0.21 11.6 0.0 2.0 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Neur_chan_LBD PF02931.23 KFM60910.1 - 2.7e-43 147.9 2.6 4.3e-43 147.3 2.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM60910.1 - 2.6e-06 27.7 15.6 6.8e-05 23.0 9.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region PH PF00169.29 KFM60912.1 - 2.7e-17 63.2 0.0 6.1e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM60912.1 - 0.00063 20.1 1.3 0.0052 17.2 0.3 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 KFM60912.1 - 0.002 18.5 0.0 0.043 14.2 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain T7SS_ESX_EspC PF10824.8 KFM60912.1 - 0.033 14.6 2.1 3.9 8.0 0.2 2.5 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm HeLo PF14479.6 KFM60912.1 - 0.034 14.0 5.9 0.11 12.4 1.5 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation DUF948 PF06103.11 KFM60912.1 - 0.51 10.6 3.5 1.8 8.9 2.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 KFM60912.1 - 0.59 10.2 8.0 0.59 10.2 5.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1840 PF08895.11 KFM60912.1 - 8.8 6.7 7.9 0.78 10.1 1.0 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF1840) Dynein_C PF18199.1 KFM60913.1 - 7.4e-10 38.5 0.5 7.6e-10 38.5 0.5 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KFM60914.1 - 5.4e-17 62.1 0.1 5.6e-17 62.0 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Fam20C PF06702.12 KFM60915.1 - 2.9e-97 324.7 0.8 4.3e-97 324.2 0.1 1.7 2 0 0 2 2 2 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 KFM60915.1 - 1.5e-05 24.1 0.0 2.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 FAM198 protein MapZ_EC1 PF18041.1 KFM60915.1 - 1.1 9.4 5.4 0.57 10.4 2.4 2.0 2 0 0 2 2 2 0 MapZ extracellular domain 1 Ammonium_transp PF00909.21 KFM60916.1 - 9.4e-13 47.6 0.1 1.1e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family zf-CCHC_4 PF14392.6 KFM60917.1 - 0.021 14.6 8.9 0.36 10.6 1.5 2.7 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 KFM60917.1 - 7.4 6.8 16.0 0.63 10.2 0.5 3.1 4 0 0 4 4 4 0 Zinc knuckle Zip PF02535.22 KFM60919.1 - 1.1e-77 261.5 7.6 1.1e-77 261.5 7.6 3.3 2 1 0 2 2 2 1 ZIP Zinc transporter EF-hand_7 PF13499.6 KFM60920.1 - 3.7e-14 52.9 0.0 4.8e-09 36.5 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM60920.1 - 2.4e-11 42.4 0.2 0.049 13.2 0.0 5.0 5 1 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFM60920.1 - 2.4e-11 42.6 0.1 0.0053 16.6 0.0 4.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KFM60920.1 - 2e-08 33.9 0.3 6e-05 22.8 0.0 3.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_10 PF14788.6 KFM60920.1 - 0.032 14.1 0.0 3.3 7.7 0.0 2.8 3 0 0 3 3 3 0 EF hand DUF5580 PF17743.1 KFM60920.1 - 0.037 12.6 0.0 0.043 12.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_11 PF08976.11 KFM60920.1 - 0.06 14.2 0.0 0.085 13.7 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain DUF1456 PF07308.13 KFM60920.1 - 0.062 13.6 0.1 7.1 7.1 0.1 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1456) EF-hand_9 PF14658.6 KFM60920.1 - 0.068 13.5 0.0 0.45 10.9 0.0 2.1 2 1 0 2 2 2 0 EF-hand domain Thioredoxin_16 PF18569.1 KFM60920.1 - 0.091 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain G-patch PF01585.23 KFM60921.1 - 8e-12 44.9 0.6 1.3e-11 44.2 0.6 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFM60921.1 - 2.3e-05 24.4 0.7 3.6e-05 23.8 0.7 1.3 1 0 0 1 1 1 1 G-patch domain HEAT PF02985.22 KFM60922.1 - 5.1e-12 45.0 1.9 0.016 15.4 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KFM60922.1 - 1.8e-09 37.9 0.2 0.046 14.2 0.0 6.5 5 2 3 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFM60922.1 - 4.4e-08 33.6 3.0 0.019 15.6 0.0 4.2 5 0 0 5 5 4 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 KFM60922.1 - 3e-07 30.3 0.4 2.8e-06 27.2 0.1 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KFM60922.1 - 3e-07 30.7 0.1 0.098 13.1 0.0 4.9 4 2 1 5 5 5 2 HEAT repeats UME PF08064.13 KFM60922.1 - 9e-07 28.8 1.4 3.1 7.7 0.0 4.6 2 2 2 4 4 4 3 UME (NUC010) domain IFRD PF05004.13 KFM60922.1 - 1.2e-05 24.6 2.2 0.00081 18.6 0.4 3.6 1 1 2 3 3 3 1 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 KFM60922.1 - 1.9e-05 24.9 3.5 1.8 8.6 0.1 3.9 2 2 2 4 4 4 2 Parkin co-regulated protein CLASP_N PF12348.8 KFM60922.1 - 0.001 18.6 0.6 0.99 8.9 0.0 4.1 3 2 1 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 KFM60922.1 - 0.0017 18.4 2.2 0.38 10.8 0.0 4.0 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KFM60922.1 - 0.0054 16.5 1.0 1.2 8.9 0.5 4.2 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 KFM60922.1 - 0.0056 15.9 7.9 0.52 9.4 0.4 3.9 3 1 2 5 5 5 2 RNAPII transcription regulator C-terminal Rhabdo_matrix PF03397.14 KFM60922.1 - 0.022 14.5 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Rhabdovirus matrix protein RTP1_C1 PF10363.9 KFM60922.1 - 0.023 14.9 1.2 55 4.0 0.0 4.6 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Importin_rep_4 PF18808.1 KFM60922.1 - 0.11 12.7 0.1 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Importin repeat Ubiq_cyt_C_chap PF03981.12 KFM60922.1 - 0.12 12.5 0.2 6.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone NDT80_PhoG PF05224.12 KFM60923.1 - 3.9e-25 89.2 0.5 1.2e-23 84.3 0.5 2.8 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.6 KFM60923.1 - 5.8e-22 76.5 1.7 1.1e-21 75.6 1.7 1.5 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Peptidase_S74 PF13884.6 KFM60923.1 - 9.1e-13 48.3 0.0 1.6e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase DUF4349 PF14257.6 KFM60923.1 - 0.0089 15.5 0.0 0.066 12.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4349) UBX PF00789.20 KFM60926.1 - 9.6e-13 48.1 0.5 1.8e-12 47.2 0.1 1.7 2 0 0 2 2 2 1 UBX domain Endonuc_Holl PF10107.9 KFM60926.1 - 7.7 6.3 10.9 11 5.8 10.9 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Presenilin PF01080.17 KFM60926.1 - 10 4.8 5.1 12 4.5 5.1 1.0 1 0 0 1 1 1 0 Presenilin DUF3421 PF11901.8 KFM60927.1 - 3.9e-37 126.8 7.1 7.2e-27 93.7 1.1 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) PSI_PsaF PF02507.15 KFM60927.1 - 0.043 13.7 0.5 0.072 12.9 0.5 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III DUF727 PF05303.12 KFM60928.1 - 1.2e-28 99.3 0.0 1.3e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF727) zf-C3HC4_3 PF13920.6 KFM60929.1 - 1.2e-07 31.5 8.1 2.5e-07 30.5 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM60929.1 - 2.9e-06 27.0 10.5 7.4e-06 25.7 10.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM60929.1 - 2.2e-05 24.2 10.8 4.8e-05 23.1 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM60929.1 - 3.3e-05 23.8 11.0 0.00012 21.9 11.1 2.0 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM60929.1 - 0.00025 20.8 6.6 0.00056 19.7 6.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFM60929.1 - 0.0003 21.0 6.1 0.00096 19.4 6.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFM60929.1 - 0.00038 20.7 9.1 0.00098 19.4 9.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFM60929.1 - 0.00048 20.1 7.6 0.0014 18.6 7.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFM60929.1 - 0.0031 17.5 1.8 0.0064 16.5 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger BRE1 PF08647.11 KFM60929.1 - 0.011 15.8 15.7 0.011 15.8 15.7 10.3 4 1 4 10 10 9 0 BRE1 E3 ubiquitin ligase SOGA PF11365.8 KFM60929.1 - 0.033 15.3 1.1 0.033 15.3 1.1 9.8 4 2 4 10 10 8 0 Protein SOGA Zn_ribbon_17 PF17120.5 KFM60929.1 - 0.15 11.7 4.3 0.28 10.8 4.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFM60929.1 - 0.28 11.4 7.2 1 9.6 7.2 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFM60929.1 - 2.6 7.9 12.6 42 4.0 12.4 2.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Peptidase_M10 PF00413.24 KFM60930.1 - 2.2e-51 173.8 0.0 4.3e-51 172.9 0.0 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFM60930.1 - 5.3e-46 154.3 13.1 3.8e-12 45.9 0.1 4.3 4 0 0 4 4 4 4 Hemopexin Reprolysin_3 PF13582.6 KFM60930.1 - 0.005 17.4 0.2 0.011 16.2 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFM60930.1 - 0.0051 16.5 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFM60930.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Astacin PF01400.24 KFM60930.1 - 0.028 14.0 0.4 0.21 11.2 0.1 2.4 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) Zn_peptidase_2 PF04298.12 KFM60930.1 - 0.066 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Reprolysin_5 PF13688.6 KFM60930.1 - 0.076 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 KFM60930.1 - 0.24 9.9 0.0 0.33 9.5 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family zf-met PF12874.7 KFM60932.1 - 0.0088 16.4 5.4 1.5 9.3 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFM60932.1 - 0.025 15.0 2.2 0.089 13.3 2.2 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type LRR_8 PF13855.6 KFM60934.1 - 2.6e-27 94.4 6.0 1e-14 54.0 0.4 2.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFM60934.1 - 2.5e-12 46.8 0.9 1.4e-08 34.9 0.3 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM60934.1 - 9.9e-07 28.8 0.0 1.3e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM60934.1 - 6.2e-06 26.0 0.8 0.4 11.4 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.6 KFM60934.1 - 2.8e-05 23.7 0.1 3.6e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KFM60934.1 - 0.00018 21.3 0.8 3.3 8.0 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeat SAM_2 PF07647.17 KFM60937.1 - 1e-32 112.0 0.8 1.2e-10 41.3 0.0 3.3 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM60937.1 - 1.3e-31 108.8 1.7 5.9e-15 55.4 0.2 3.5 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFM60937.1 - 0.0011 18.9 0.2 1.7 8.6 0.0 3.2 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain Bro-N PF02498.17 KFM60937.1 - 0.075 13.7 0.0 0.23 12.2 0.0 1.8 1 0 0 1 1 1 0 BRO family, N-terminal domain TMEM135_C_rich PF15982.5 KFM60938.1 - 2.5e-48 164.0 4.8 6e-48 162.8 4.8 1.6 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 KFM60938.1 - 0.00042 20.7 1.6 0.0034 17.7 0.2 2.3 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Crust_neurohorm PF01147.17 KFM60939.1 - 8.1e-22 76.8 7.2 9.7e-22 76.6 7.2 1.1 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family BAF PF02961.14 KFM60941.1 - 1.8e-44 150.1 0.2 2e-44 149.9 0.2 1.0 1 0 0 1 1 1 1 Barrier to autointegration factor M20_dimer PF07687.14 KFM60942.1 - 8.7e-12 44.9 0.0 2.2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KFM60942.1 - 2.4e-06 27.4 0.2 4.1e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFM60943.1 - 1.2e-09 38.0 0.2 4e-09 36.4 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KFM60943.1 - 1e-08 35.1 0.1 1.7e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.28 KFM60944.1 - 0.00015 21.6 0.2 0.00022 21.0 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Col_cuticle_N PF01484.17 KFM60944.1 - 0.23 11.5 0.9 0.4 10.8 0.9 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain IFP_35_N PF07334.13 KFM60945.1 - 3.5 7.8 6.2 6.2 7.0 0.4 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TIP49 PF06068.13 KFM60946.1 - 1e-168 561.1 1.7 1.3e-168 560.7 1.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFM60946.1 - 2.1e-21 75.8 0.1 6.9e-21 74.2 0.1 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KFM60946.1 - 7.1e-12 45.9 2.4 5.6e-08 33.3 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFM60946.1 - 7.8e-10 38.7 0.4 5.9e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFM60946.1 - 5.1e-08 33.3 0.1 0.0049 17.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFM60946.1 - 7.8e-05 23.1 0.0 0.0027 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFM60946.1 - 0.0002 21.4 0.1 0.048 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFM60946.1 - 0.00051 19.8 0.1 0.94 9.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 KFM60946.1 - 0.00079 19.1 0.1 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFM60946.1 - 0.0012 19.1 3.6 0.024 15.0 3.6 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFM60946.1 - 0.0016 17.9 0.3 0.097 12.0 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFM60946.1 - 0.0018 18.8 0.0 0.028 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KFM60946.1 - 0.006 16.6 0.0 2.6 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFM60946.1 - 0.0099 15.7 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KFM60946.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Rad17 PF03215.15 KFM60946.1 - 0.014 15.3 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 KFM60946.1 - 0.015 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFM60946.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KFM60946.1 - 0.022 14.5 0.6 0.83 9.3 0.1 2.8 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 KFM60946.1 - 0.027 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 KFM60946.1 - 0.032 14.0 0.1 0.032 14.0 0.1 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFM60946.1 - 0.037 14.2 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFM60946.1 - 0.048 13.2 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KFM60946.1 - 0.056 13.3 0.2 0.22 11.4 0.0 2.2 2 0 0 2 2 1 0 NTPase GvpD PF07088.11 KFM60946.1 - 0.061 11.9 0.0 0.45 9.1 0.0 2.0 2 0 0 2 2 2 0 GvpD gas vesicle protein PhoH PF02562.16 KFM60946.1 - 0.069 12.6 0.1 0.069 12.6 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 KFM60946.1 - 0.14 11.4 1.9 0.15 11.3 0.1 1.9 3 0 0 3 3 3 0 Zeta toxin ResIII PF04851.15 KFM60946.1 - 0.22 11.5 5.0 0.31 11.0 0.0 2.5 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit CbiA PF01656.23 KFM60946.1 - 0.3 11.2 1.9 5.4 7.1 0.2 2.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain COX17 PF05051.13 KFM60947.1 - 6.2e-09 36.1 6.1 6.2e-09 36.1 6.1 1.5 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) YccV-like PF08755.11 KFM60948.1 - 7.2e-14 52.1 0.3 1.2e-13 51.3 0.3 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Y_Y_Y PF07495.13 KFM60952.1 - 0.0055 16.6 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 Y_Y_Y domain FUN14 PF04930.15 KFM60953.1 - 3.2e-25 88.4 2.8 3.2e-25 88.4 2.8 1.4 2 0 0 2 2 2 1 FUN14 family UvrA_inter PF17760.1 KFM60953.1 - 0.024 14.7 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 UvrA interaction domain SLATT_1 PF18181.1 KFM60953.1 - 0.19 11.7 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Memo PF01875.17 KFM60956.1 - 6.4e-15 55.0 0.2 6.8e-15 54.9 0.2 1.0 1 0 0 1 1 1 1 Memo-like protein SERTA PF06031.13 KFM60958.1 - 1.2e-07 31.3 0.0 1.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 SERTA motif DDE_Tnp_IS1595 PF12762.7 KFM60959.1 - 3.1e-19 69.5 0.1 4.3e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.6 KFM60959.1 - 0.0092 15.7 0.1 0.48 10.2 0.0 2.5 2 1 0 2 2 2 1 DDE superfamily endonuclease CRAL_TRIO PF00650.20 KFM60960.1 - 5.7e-14 52.1 0.2 5.7e-14 52.1 0.2 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain Toxin_9 PF02819.15 KFM60961.1 - 0.0058 16.9 19.3 0.012 15.8 19.3 1.6 1 1 1 2 2 2 1 Spider toxin Ribosomal_L35Ae PF01247.18 KFM60965.1 - 1.2e-28 99.1 1.3 1.9e-28 98.4 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae CENP-M PF11111.8 KFM60965.1 - 0.05 12.8 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) OAD_gamma PF04277.13 KFM60965.1 - 1.5 9.4 4.2 0.35 11.5 1.3 1.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_S7e PF01251.18 KFM60966.1 - 2.4e-73 245.8 7.3 2.6e-73 245.7 7.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e THF_DHG_CYH_C PF02882.19 KFM60966.1 - 0.055 12.8 0.3 0.41 10.0 0.0 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Nup35_RRM_2 PF14605.6 KFM60967.1 - 2.2e-07 30.7 0.1 0.001 19.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KFM60967.1 - 2.1e-06 27.5 1.4 0.0044 16.8 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KFM60967.1 - 2e-05 24.8 0.1 4.4e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KFM60967.1 - 0.00095 19.0 1.3 0.0019 18.1 1.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM60967.1 - 0.31 11.1 2.8 0.28 11.3 1.0 1.9 2 0 0 2 2 2 0 Zinc finger domain Vir_act_alpha_C PF10400.9 KFM60969.1 - 1.2 9.9 9.4 4 8.2 0.0 3.5 4 0 0 4 4 4 0 Virulence activator alpha C-term ALMS_motif PF15309.6 KFM60970.1 - 2.8e-09 37.6 3.3 2.8e-09 37.6 3.3 3.2 4 0 0 4 4 4 1 ALMS motif PIP5K PF01504.18 KFM60971.1 - 4.9e-72 242.4 0.0 6.2e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Inositol_P PF00459.25 KFM60972.1 - 2e-31 109.5 1.9 2e-31 109.5 1.9 1.8 1 1 1 2 2 2 2 Inositol monophosphatase family DUF5398 PF17376.2 KFM60972.1 - 0.056 14.1 1.9 0.13 12.9 1.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5398) UDPG_MGDP_dh PF00984.19 KFM60973.1 - 4.4e-30 103.7 0.0 6.9e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KFM60973.1 - 4.5e-28 97.7 0.0 1e-27 96.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.14 KFM60973.1 - 6.5e-11 42.1 0.0 1.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFM60974.1 - 6.5e-15 55.2 0.0 7.1e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFM60974.1 - 0.004 17.4 0.0 0.0042 17.4 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KFM60974.1 - 0.059 13.2 0.0 0.064 13.1 0.0 1.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PACT_coil_coil PF10495.9 KFM60976.1 - 1.7e-10 41.3 0.3 1.7e-10 41.3 0.3 5.7 6 0 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CARD PF00619.21 KFM60977.1 - 0.021 14.8 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Caspase recruitment domain NB-ARC PF00931.22 KFM60978.1 - 1.6e-25 89.8 0.0 1.8e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KFM60978.1 - 0.00087 19.6 0.0 0.0037 17.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFM60978.1 - 0.0011 19.4 0.0 0.0034 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFM60978.1 - 0.0041 17.5 0.0 0.033 14.6 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFM60978.1 - 0.026 15.1 0.1 0.063 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM60978.1 - 0.041 13.8 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 KFM60978.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KFM60978.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KFM60978.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM60978.1 - 0.18 11.9 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain APAF1_C PF17908.1 KFM60979.1 - 3.8e-16 59.3 0.5 5.3e-16 58.9 0.5 1.2 1 0 0 1 1 1 1 APAF-1 helical domain WD40 PF00400.32 KFM60979.1 - 2.6e-11 43.9 0.6 1.3e-08 35.4 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40_like PF17005.5 KFM60979.1 - 0.00051 19.5 0.2 0.00051 19.5 0.2 1.5 2 0 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 KFM60979.1 - 0.0022 18.2 0.1 0.027 14.8 0.1 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM60979.1 - 0.0038 16.2 0.3 0.022 13.7 0.3 1.8 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KFM60980.1 - 2.1e-27 94.8 37.4 2.1e-06 28.3 0.3 10.8 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM60980.1 - 3.5e-13 49.7 2.1 0.0022 18.2 0.0 6.2 3 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM60980.1 - 4.4e-09 36.1 7.9 0.00026 20.4 4.0 3.4 1 1 2 3 3 3 3 WD40-like domain Nup160 PF11715.8 KFM60980.1 - 7.4e-06 24.9 2.7 0.0023 16.6 0.0 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Hira PF07569.11 KFM60980.1 - 0.15 11.7 2.0 4.6 6.9 0.3 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split zf-C2H2 PF00096.26 KFM60982.1 - 8.8e-25 85.7 128.8 0.00013 22.2 1.9 15.1 15 0 0 15 15 15 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM60982.1 - 5.7e-24 82.7 127.5 0.00063 20.4 1.2 16.0 15 1 1 16 16 16 13 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM60982.1 - 5.7e-18 64.4 20.1 1.4e-07 31.6 0.6 16.7 19 1 0 19 19 19 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM60982.1 - 1.4e-10 40.8 20.6 1.8e-08 34.0 3.2 12.8 13 1 0 13 13 13 6 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM60982.1 - 0.00025 21.3 1.3 0.00025 21.3 1.3 12.7 7 5 5 12 12 12 4 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFM60982.1 - 0.00067 19.9 0.5 0.011 16.0 0.2 13.3 13 1 1 14 14 14 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM60982.1 - 0.039 14.4 0.0 0.039 14.4 0.0 12.5 14 0 0 14 14 14 0 Zinc-finger of C2H2 type PulA_N1 PF17999.1 KFM60982.1 - 0.53 11.1 2.3 3.2 8.5 0.7 3.0 2 0 0 2 2 2 0 Pullulanase N1-terminal domain UQ_con PF00179.26 KFM60983.1 - 1.4e-46 157.6 0.0 1.6e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM60983.1 - 0.00029 20.6 0.0 0.00038 20.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFM60983.1 - 0.0095 15.8 0.2 0.019 14.8 0.2 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KFM60983.1 - 0.098 13.0 0.4 0.16 12.2 0.4 1.5 1 1 0 1 1 1 0 RWD domain NADH_oxidored PF08040.11 KFM60985.1 - 2.7e-11 43.0 0.1 3e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 MNLL subunit Glyco_transf_43 PF03360.16 KFM60986.1 - 6.4e-78 261.3 0.0 8.4e-78 260.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 UQ_con PF00179.26 KFM60987.1 - 3.4e-44 149.9 0.1 3.7e-44 149.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM60987.1 - 0.0098 16.2 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFM60987.1 - 0.02 14.6 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KFM60987.1 - 0.046 13.6 0.1 0.069 13.0 0.1 1.3 1 1 0 1 1 1 0 UEV domain Peptidase_M24 PF00557.24 KFM60988.1 - 3.8e-44 150.9 0.3 5.8e-44 150.3 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFM60988.1 - 2.3e-25 88.7 0.0 4.2e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 KFM60988.1 - 0.12 12.4 0.1 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) Q_salvage PF10343.9 KFM60990.1 - 4.6e-117 390.6 0.2 5.5e-117 390.4 0.2 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 KFM60990.1 - 6.4e-05 21.8 0.0 0.0039 16.0 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1688) Lectin_leg-like PF03388.13 KFM60991.1 - 2.7e-87 291.9 0.5 3.9e-87 291.4 0.5 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFM60991.1 - 1.8e-10 41.1 2.0 3.2e-10 40.4 2.0 1.3 1 0 0 1 1 1 1 Bacterial lectin ATP-synt_E PF05680.12 KFM60991.1 - 0.98 9.8 5.5 2.5 8.5 5.5 1.7 1 0 0 1 1 1 0 ATP synthase E chain tify PF06200.14 KFM60992.1 - 0.023 14.0 0.2 0.033 13.5 0.2 1.4 1 1 0 1 1 1 0 tify domain DUF445 PF04286.12 KFM60995.1 - 0.0035 17.2 4.4 0.036 13.9 4.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF445) CCDC117 PF15810.5 KFM60995.1 - 0.078 13.3 7.3 7.7 6.8 0.4 4.8 1 1 3 4 4 4 0 Coiled-coil domain-containing protein 117 CEL_III_C PF18054.1 KFM60995.1 - 3.5 7.7 74.7 0.48 10.5 10.2 6.5 1 1 6 7 7 7 0 CEL-III C-terminal YueH PF14166.6 KFM60995.1 - 4.2 7.3 38.1 13 5.8 0.3 9.1 2 2 5 8 8 8 0 YueH-like protein Headcase PF16002.5 KFM60996.1 - 1.1e-87 292.7 7.9 1.1e-87 292.7 7.9 1.7 2 0 0 2 2 2 1 Headcase protein HECA PF15353.6 KFM60996.1 - 1.5e-47 160.0 5.8 3.9e-47 158.7 5.8 1.7 1 0 0 1 1 1 1 Headcase protein family homologue Zn-ribbon_8 PF09723.10 KFM60996.1 - 0.0061 16.6 0.3 0.0061 16.6 0.3 2.6 3 0 0 3 3 3 1 Zinc ribbon domain HypA PF01155.19 KFM60996.1 - 1.3 9.1 5.6 18 5.4 5.6 2.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sugar_tr PF00083.24 KFM60998.1 - 3.4e-129 431.6 19.1 4e-129 431.4 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM60998.1 - 6.3e-21 74.7 24.6 6.3e-21 74.7 24.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KFM60998.1 - 4.5 5.4 9.0 8.3 4.6 9.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ubiquitin PF00240.23 KFM60999.1 - 0.037 13.8 0.1 0.13 12.0 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin family MOZ_SAS PF01853.18 KFM61001.1 - 6.5e-86 286.6 0.3 8.8e-86 286.1 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFM61001.1 - 3.4e-24 84.2 4.5 3.4e-24 84.2 4.5 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KFM61001.1 - 0.0016 18.8 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_11 PF08279.12 KFM61001.1 - 0.043 13.8 0.3 0.081 12.9 0.3 1.4 1 0 0 1 1 1 0 HTH domain Acetyltransf_1 PF00583.25 KFM61001.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TFIIE_beta PF02186.15 KFM61001.1 - 0.084 13.2 0.1 0.43 10.9 0.0 2.1 2 0 0 2 2 2 0 TFIIE beta subunit core domain Utp12 PF04003.12 KFM61002.1 - 1.4e-19 70.3 1.3 3.3e-19 69.2 1.3 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KFM61002.1 - 1.4e-08 35.2 8.4 0.0061 17.4 3.2 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM61002.1 - 8.5e-07 29.2 0.2 0.00057 20.1 0.1 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM61002.1 - 0.0001 21.8 0.6 0.00039 19.9 0.1 2.0 2 0 0 2 2 2 1 WD40-like domain DUF829 PF05705.14 KFM61003.1 - 0.065 13.1 0.6 0.13 12.2 0.6 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) DUF641 PF04859.12 KFM61003.1 - 0.11 12.8 30.9 0.52 10.6 2.5 3.5 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) Bcr-Abl_Oligo PF09036.10 KFM61003.1 - 0.4 10.7 0.1 0.4 10.7 0.1 2.9 3 1 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DUF1843 PF08898.10 KFM61003.1 - 1.2 9.6 4.6 5.5 7.6 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) DUF1664 PF07889.12 KFM61004.1 - 0.093 12.8 7.6 0.26 11.3 2.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tho2 PF11262.8 KFM61004.1 - 0.13 11.4 8.0 0.17 11.1 8.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ACCA PF03255.14 KFM61004.1 - 0.59 10.0 11.6 4.7 7.1 2.3 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1640 PF07798.11 KFM61004.1 - 1.2 9.2 15.8 2 8.4 14.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) YabA PF06156.13 KFM61004.1 - 1.9 9.2 15.6 1.3 9.7 6.8 2.2 1 1 1 2 2 2 0 Initiation control protein YabA GLTSCR1 PF15249.6 KFM61004.1 - 7.5 7.1 10.9 2.3e+02 2.3 10.9 2.2 1 1 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein SlyX PF04102.12 KFM61004.1 - 7.6 7.2 10.4 8.5 7.1 4.0 2.3 2 0 0 2 2 2 0 SlyX bZIP_2 PF07716.15 KFM61004.1 - 8.4 6.6 19.3 10 6.3 1.2 3.4 2 1 1 3 3 3 0 Basic region leucine zipper zf-C2H2 PF00096.26 KFM61005.1 - 8.9e-09 35.3 6.8 0.00013 22.2 0.9 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61005.1 - 2.8e-07 30.8 4.3 0.00022 21.8 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM61005.1 - 1.6e-06 27.8 2.5 3.1e-05 23.6 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM61005.1 - 5.6e-05 23.4 2.3 0.043 14.2 0.2 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM61005.1 - 0.0013 19.1 13.6 0.0022 18.3 1.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM61005.1 - 0.0015 18.8 0.3 0.0015 18.8 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM61005.1 - 0.0018 18.6 0.1 0.0042 17.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KFM61005.1 - 0.013 16.2 0.3 5 7.8 0.0 2.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KFM61005.1 - 0.024 14.9 3.6 0.041 14.2 3.6 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFM61005.1 - 0.058 13.4 1.9 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFM61005.1 - 0.47 10.1 3.7 2.8 7.7 0.7 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 KFM61006.1 - 5.3e-08 32.9 14.3 1.5e-07 31.5 1.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM61006.1 - 0.00025 20.7 16.3 0.0004 20.1 0.9 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM61006.1 - 0.0036 17.7 15.3 0.031 14.7 6.0 2.5 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61006.1 - 0.011 16.6 13.2 0.13 13.2 4.6 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KFM61006.1 - 0.052 13.6 1.5 0.052 13.6 1.5 2.2 1 1 1 2 2 2 0 BED zinc finger Cytochrom_CIII PF02085.16 KFM61006.1 - 0.34 11.3 8.4 0.39 11.1 8.4 1.1 1 0 0 1 1 1 0 Class III cytochrome C family Elf1 PF05129.13 KFM61006.1 - 0.43 10.7 5.7 0.88 9.7 0.7 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 KFM61006.1 - 2.7 8.1 7.8 1 9.4 5.0 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain GAGA PF09237.11 KFM61006.1 - 3.9 7.4 9.4 6.7 6.6 1.8 2.1 1 1 1 2 2 2 0 GAGA factor zf-H2C2_2 PF13465.6 KFM61007.1 - 6.1e-11 42.2 13.0 9.6e-09 35.3 0.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM61007.1 - 9.7e-11 41.5 11.9 2.3e-06 27.8 0.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61007.1 - 1.5e-07 31.7 11.0 0.00028 21.5 0.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM61007.1 - 1.1e-05 25.6 6.1 0.02 15.3 1.2 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM61007.1 - 4.2e-05 23.4 9.3 0.0067 16.4 5.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM61007.1 - 0.00081 19.6 3.2 0.6 10.5 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 KFM61007.1 - 0.0012 18.4 3.8 0.017 14.7 0.4 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain zf-C2H2_11 PF16622.5 KFM61007.1 - 0.0057 16.4 10.7 0.08 12.7 0.9 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KFM61007.1 - 0.011 16.0 2.9 0.012 15.9 2.9 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon DUF2256 PF10013.9 KFM61007.1 - 0.014 15.5 0.5 2.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-UBP PF02148.19 KFM61007.1 - 0.026 14.9 3.5 0.27 11.6 3.5 2.0 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Zf_RING PF16744.5 KFM61007.1 - 0.04 14.0 3.6 1.4 9.1 0.1 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger FYVE PF01363.21 KFM61007.1 - 0.057 13.6 4.8 0.09 12.9 4.8 1.4 1 1 0 1 1 1 0 FYVE zinc finger Cas_CXXC_CXXC PF09706.10 KFM61007.1 - 0.12 12.6 0.3 0.12 12.6 0.3 1.7 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-H2C2_5 PF13909.6 KFM61007.1 - 0.23 11.3 0.2 0.23 11.3 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM61007.1 - 0.26 11.7 7.9 0.32 11.3 0.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM61010.1 - 7.7e-61 200.0 64.5 5.6e-08 32.9 0.9 10.9 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM61010.1 - 6.5e-45 149.2 78.1 1.4e-06 28.4 1.4 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61010.1 - 3.6e-36 120.7 73.5 0.0002 21.9 0.6 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM61010.1 - 1e-23 82.9 64.4 0.0013 19.1 1.0 10.3 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM61010.1 - 2.9e-15 56.1 46.2 0.39 11.1 0.6 10.3 10 0 0 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM61010.1 - 1.9e-12 46.9 62.2 0.042 13.8 0.5 10.1 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM61010.1 - 8.5e-12 44.7 34.3 0.63 9.9 0.2 9.9 2 2 8 10 10 10 4 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM61010.1 - 7.7e-09 35.5 33.1 5.4 7.2 0.1 10.0 10 0 0 10 10 10 1 DBF zinc finger zf-H2C2_5 PF13909.6 KFM61010.1 - 5.8e-08 32.4 43.1 0.054 13.3 0.4 9.6 9 0 0 9 9 9 3 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM61010.1 - 5.1e-07 29.6 30.3 2.1 8.5 0.1 9.8 8 2 2 10 10 10 2 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM61010.1 - 5.5e-07 29.3 29.7 1.7 8.5 0.1 9.0 1 1 8 9 9 9 4 GAGA factor ADK_lid PF05191.14 KFM61010.1 - 3e-06 27.1 29.2 0.69 9.9 0.2 6.3 3 1 5 8 8 8 4 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM61010.1 - 9.5e-05 22.7 61.6 1.6 9.1 0.4 9.5 1 1 6 8 8 8 2 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFM61010.1 - 0.00013 22.2 14.4 2.9 8.2 0.5 6.0 1 1 5 6 6 6 1 BolA-like protein zf-RRPl_C4 PF17026.5 KFM61010.1 - 0.00015 21.9 37.6 0.082 13.0 10.7 4.5 1 1 1 3 3 3 2 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2HC_2 PF13913.6 KFM61010.1 - 0.00093 19.0 35.1 0.083 12.8 0.4 9.0 9 0 0 9 9 9 1 zinc-finger of a C2HC-type PPL4 PF18188.1 KFM61010.1 - 0.0018 18.2 2.9 1 9.3 0.0 4.3 3 1 2 5 5 4 1 Prim-pol 4 zf_UBZ PF18439.1 KFM61010.1 - 0.0025 17.4 42.2 1.1 8.9 0.2 9.2 10 0 0 10 10 10 3 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 KFM61010.1 - 0.0062 16.4 33.6 8.3 6.4 2.1 9.4 9 1 0 9 9 9 0 Prokaryotic RING finger family 1 zf-MYST PF17772.1 KFM61010.1 - 0.0067 16.0 48.0 0.76 9.4 0.3 9.7 4 3 6 10 10 10 3 MYST family zinc finger domain Zn-ribbon_8 PF09723.10 KFM61010.1 - 0.0093 16.1 34.2 1.1 9.4 0.4 6.3 5 2 0 6 6 6 3 Zinc ribbon domain DUF2256 PF10013.9 KFM61010.1 - 0.011 15.8 35.8 11 6.2 0.1 9.7 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFM61010.1 - 0.032 15.0 37.7 0.83 10.5 2.6 5.5 1 1 6 7 7 7 0 zinc-ribbon family DUF4825 PF16107.5 KFM61010.1 - 0.074 13.2 0.0 5.8 7.1 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4825) Baculo_IE-1 PF05290.11 KFM61010.1 - 0.21 11.6 35.9 1.8 8.5 0.6 7.1 1 1 2 4 4 4 0 Baculovirus immediate-early protein (IE-0) zf-CHCC PF10276.9 KFM61010.1 - 0.24 11.5 20.2 49 4.1 0.1 8.0 10 0 0 10 10 9 0 Zinc-finger domain NAD_kinase PF01513.21 KFM61010.1 - 0.27 10.4 0.6 22 4.1 0.1 2.8 1 1 2 3 3 3 0 ATP-NAD kinase TRAF6_Z2 PF18048.1 KFM61010.1 - 2.9 8.1 31.0 0.19 11.8 0.8 6.8 8 0 0 8 8 7 0 TNF receptor-associated factor 6 zinc finger 2 PqqA PF08042.11 KFM61010.1 - 4 7.6 7.9 2.2e+02 2.1 0.0 5.6 7 0 0 7 7 7 0 PqqA family Scramblase PF03803.15 KFM61010.1 - 4.9 6.4 10.0 12 5.1 0.4 3.1 1 1 3 4 4 4 0 Scramblase FYVE PF01363.21 KFM61010.1 - 6.3 7.0 48.1 1.2e+02 2.9 7.4 6.0 2 2 2 4 4 4 0 FYVE zinc finger Pox_VLTF3 PF04947.14 KFM61012.1 - 0.0049 16.6 0.2 0.005 16.6 0.2 1.0 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like SNF PF00209.18 KFM61014.1 - 2.1e-231 769.2 28.9 2.4e-231 769.0 28.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family MWFE PF15879.5 KFM61014.1 - 0.67 10.2 5.1 6.3 7.0 1.1 3.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit F-box-like PF12937.7 KFM61015.1 - 0.00062 19.6 0.7 0.0013 18.6 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM61015.1 - 0.023 14.6 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 F-box domain TMEM237 PF15383.6 KFM61015.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 ORC6 PF05460.13 KFM61015.1 - 2.3 7.4 5.8 2.8 7.1 5.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) G_glu_transpept PF01019.21 KFM61016.1 - 7.9e-113 377.9 0.0 9.7e-113 377.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cyc-maltodext_C PF10438.9 KFM61016.1 - 0.039 14.0 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain zf-CCCH PF00642.24 KFM61017.1 - 5.8e-09 35.6 5.1 1.6e-06 27.9 0.7 6.5 7 0 0 7 7 7 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM61017.1 - 6.7e-06 26.0 32.5 0.01 15.9 0.3 6.4 6 1 0 6 6 6 4 Zinc finger domain Torus PF16131.5 KFM61017.1 - 0.035 14.8 0.2 0.035 14.8 0.2 4.9 3 2 2 5 5 5 0 Torus domain Peptidase_S28 PF05577.12 KFM61020.1 - 1.8e-93 313.7 0.0 2.1e-93 313.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KFM61020.1 - 3.4e-05 22.7 0.0 5.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 KFM61020.1 - 0.00015 21.1 0.0 0.00021 20.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFM61020.1 - 0.0007 19.1 0.2 0.0024 17.4 0.1 1.9 1 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFM61020.1 - 0.0025 17.5 0.1 0.064 12.9 0.0 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM61020.1 - 0.01 16.5 0.0 0.05 14.2 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.8 KFM61020.1 - 0.024 13.8 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) cNMP_binding PF00027.29 KFM61021.1 - 4.2e-42 142.1 0.2 9.6e-15 54.4 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KFM61021.1 - 1.6e-22 80.7 0.0 3e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Homeodomain PF00046.29 KFM61022.1 - 8.3e-22 76.8 2.1 1.1e-21 76.4 2.1 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM61022.1 - 7.7e-05 22.5 0.1 0.00018 21.3 0.1 1.7 1 1 1 2 2 2 1 Homeobox KN domain ADH_zinc_N PF00107.26 KFM61023.1 - 7e-25 87.5 0.0 1.2e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM61023.1 - 9.4e-13 48.0 0.8 1.4e-11 44.2 0.4 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFM61023.1 - 6.4e-07 30.5 0.0 1.3e-06 29.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FimA PF16970.5 KFM61023.1 - 0.00033 20.9 0.0 0.00071 19.8 0.0 1.5 1 0 0 1 1 1 1 Type-1 fimbrial protein, A TrkA_N PF02254.18 KFM61023.1 - 0.0014 18.9 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain YAcAr PF10686.9 KFM61023.1 - 0.0067 16.4 0.8 0.017 15.1 0.8 1.6 1 0 0 1 1 1 1 YspA, cpYpsA-related SLOG family ADH_N_2 PF16884.5 KFM61023.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFM61024.1 - 5.2e-25 87.9 0.2 1.2e-24 86.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM61024.1 - 2.1e-10 40.4 0.2 2.1e-10 40.4 0.2 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFM61024.1 - 7.9e-09 36.7 0.0 2e-08 35.3 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KFM61024.1 - 0.043 14.1 0.1 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain E1-N PF14463.6 KFM61024.1 - 0.069 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 E1 N-terminal domain TYW3 PF02676.14 KFM61025.1 - 8.3e-18 64.5 0.3 8.6e-18 64.5 0.3 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 IL8 PF00048.20 KFM61025.1 - 0.016 15.4 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like TYW3 PF02676.14 KFM61026.1 - 1.6e-25 89.7 0.0 1.8e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 DDE_3 PF13358.6 KFM61029.1 - 1.7e-05 24.6 0.0 6.2e-05 22.8 0.0 1.8 1 1 1 2 2 2 2 DDE superfamily endonuclease LRR_8 PF13855.6 KFM61030.1 - 3.4e-133 433.5 144.5 2.1e-14 53.0 3.0 19.9 8 4 16 24 24 24 23 Leucine rich repeat LRR_4 PF12799.7 KFM61030.1 - 6.3e-57 188.6 154.4 4.6e-06 26.9 0.7 22.6 13 4 13 28 28 28 22 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM61030.1 - 1e-48 164.5 13.6 1.1e-10 41.6 2.1 9.6 3 3 7 11 11 11 10 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM61030.1 - 1e-21 74.1 131.7 0.15 12.7 0.1 31.6 34 3 1 35 35 35 11 Leucine Rich Repeat LRR_9 PF14580.6 KFM61030.1 - 2.2e-19 69.6 53.6 0.00054 19.5 0.9 10.4 2 2 7 11 11 11 10 Leucine-rich repeat FNIP PF05725.12 KFM61030.1 - 0.003 17.7 0.8 0.24 11.6 0.3 4.4 3 1 0 3 3 3 1 FNIP Repeat DUF5357 PF17310.2 KFM61030.1 - 0.07 11.7 0.0 0.25 9.8 0.0 1.8 3 0 0 3 3 3 0 Family of unknown function (DUF5357) LRR_6 PF13516.6 KFM61030.1 - 2.3 8.5 131.8 0.82 9.9 0.7 25.1 28 0 0 28 28 28 0 Leucine Rich repeat RPE65 PF03055.15 KFM61033.1 - 1.1e-64 219.3 0.0 1.2e-64 219.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein UPF0242 PF06785.11 KFM61034.1 - 0.11 12.5 1.2 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus OAD_gamma PF04277.13 KFM61034.1 - 0.65 10.6 3.7 5 7.8 0.0 2.7 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain BTB PF00651.31 KFM61035.1 - 5.3e-12 45.9 0.1 9.6e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM61035.1 - 6.5e-07 29.4 0.3 5.1e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 BTB And C-terminal Kelch tRNA-synt_1 PF00133.22 KFM61036.1 - 2.7e-18 65.6 0.0 2.7e-08 32.5 0.0 3.2 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KFM61036.1 - 2.4e-09 37.0 0.0 9e-09 35.1 0.0 1.8 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Anticodon_1 PF08264.13 KFM61036.1 - 1.1e-07 31.9 0.0 2.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFM61036.1 - 2.5e-05 23.2 0.1 0.017 13.9 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) zf-ribbon_3 PF13248.6 KFM61036.1 - 0.015 14.7 1.9 0.12 11.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 KFM61036.1 - 0.17 11.9 2.8 0.96 9.5 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 KFM61036.1 - 1.2 9.3 3.5 1.9 8.7 0.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF5633 PF18656.1 KFM61037.1 - 0.15 11.9 0.4 0.22 11.4 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5633) Ribosomal_L13e PF01294.18 KFM61038.1 - 5e-79 264.3 9.4 5.7e-79 264.1 9.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e tRNA-synt_2d PF01409.20 KFM61039.1 - 6.6e-48 163.3 0.0 4.8e-29 101.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KFM61039.1 - 1.2e-20 73.8 0.1 3.3e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 KFM61039.1 - 0.0038 16.4 0.5 0.086 11.9 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Complex1_LYR PF05347.15 KFM61040.1 - 1.4e-18 66.7 3.7 1.9e-18 66.2 3.7 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFM61040.1 - 1.2e-06 29.2 2.0 1.3e-06 29.0 2.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KFM61040.1 - 0.00018 22.0 0.1 0.00022 21.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RNase_H_2 PF13482.6 KFM61040.1 - 0.026 14.5 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 RNase_H superfamily Defensin_2 PF01097.18 KFM61041.1 - 8.7e-12 44.8 11.0 1.1e-11 44.5 11.0 1.1 1 0 0 1 1 1 1 Arthropod defensin Gamma-thionin PF00304.20 KFM61041.1 - 2.8e-05 24.3 9.2 3.3e-05 24.1 9.2 1.1 1 0 0 1 1 1 1 Gamma-thionin family Toxin_38 PF14866.6 KFM61041.1 - 0.0011 19.2 5.1 0.0013 18.9 5.1 1.2 1 0 0 1 1 1 1 Potassium channel toxin Toxin_3 PF00537.18 KFM61041.1 - 0.0036 17.5 8.5 0.0041 17.3 8.5 1.1 1 0 0 1 1 1 1 Scorpion toxin-like domain IGFBP PF00219.18 KFM61043.1 - 0.00061 20.4 13.5 0.0011 19.5 13.5 1.4 1 0 0 1 1 1 1 Insulin-like growth factor binding protein fn3 PF00041.21 KFM61044.1 - 1.3e-10 41.5 1.6 0.043 14.2 0.0 3.9 3 1 0 3 3 3 3 Fibronectin type III domain DUF2369 PF10179.9 KFM61044.1 - 0.00019 21.8 2.2 0.072 13.5 0.2 3.1 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFM61044.1 - 0.0005 20.3 1.3 5.8 7.3 0.0 3.5 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KFM61044.1 - 0.0012 19.4 7.7 8.4 7.0 0.0 4.4 2 1 1 3 3 3 1 Purple acid Phosphatase, N-terminal domain DUF4912 PF16258.5 KFM61044.1 - 0.011 15.9 0.1 3.9 7.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4912) VWC PF00093.18 KFM61044.1 - 1 9.7 4.1 1.9 8.9 4.1 1.5 1 0 0 1 1 1 0 von Willebrand factor type C domain TPR_8 PF13181.6 KFM61046.1 - 2.5e-06 27.2 2.3 0.042 14.1 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM61046.1 - 0.00018 21.4 2.5 0.084 13.0 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM61046.1 - 0.00051 20.5 0.1 0.0016 18.9 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM61046.1 - 0.0006 19.6 1.3 0.0013 18.6 0.0 2.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM61046.1 - 0.00084 20.0 0.2 0.58 11.1 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM61046.1 - 0.0014 18.2 0.2 0.76 9.5 0.0 3.1 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 KFM61046.1 - 0.0024 18.1 0.0 0.0049 17.1 0.0 1.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFM61046.1 - 0.055 14.1 0.1 1.1 10.0 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM61046.1 - 0.092 13.2 0.1 2.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM61046.1 - 0.12 12.3 3.2 0.72 9.8 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat FlaC_arch PF05377.11 KFM61048.1 - 0.11 12.9 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Med18 PF09637.10 KFM61049.1 - 7.7e-30 104.5 0.0 3.2e-22 79.6 0.0 2.0 1 1 1 2 2 2 2 Med18 protein GST_C PF00043.25 KFM61050.1 - 9.4e-08 32.2 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFM61050.1 - 2.3e-05 24.5 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM61050.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BTB_2 PF02214.22 KFM61051.1 - 1.8e-23 82.7 0.0 3.1e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFM61051.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFM61051.1 - 0.094 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Sulfotransfer_1 PF00685.27 KFM61052.1 - 5.8e-40 137.4 0.0 7.5e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM61052.1 - 8.1e-20 72.1 0.1 1.8e-12 48.1 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFM61052.1 - 0.033 14.1 0.0 0.071 13.0 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase family WD40 PF00400.32 KFM61053.1 - 1.1e-05 26.0 2.7 0.011 16.6 0.3 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat Utp14 PF04615.13 KFM61056.1 - 0.43 9.1 11.8 0.51 8.8 11.8 1.1 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 KFM61056.1 - 2 5.4 18.0 2.3 5.2 18.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 KFM61056.1 - 10 4.6 9.4 12 4.2 9.4 1.2 1 0 0 1 1 1 0 Macoilin family FYVE PF01363.21 KFM61057.1 - 1.3e-19 70.0 11.7 2.2e-19 69.3 11.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KFM61057.1 - 0.023 14.9 6.3 0.041 14.1 6.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 KFM61057.1 - 0.064 13.6 6.1 0.064 13.6 6.1 1.8 2 0 0 2 2 2 0 C1 domain zf-B_box PF00643.24 KFM61057.1 - 3.5 7.9 13.6 8 6.7 10.0 2.6 2 1 0 2 2 2 0 B-box zinc finger DUF2318 PF10080.9 KFM61057.1 - 7.1 6.8 9.5 2.5 8.3 5.1 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Alpha_L_fucos PF01120.17 KFM61058.1 - 0.044 13.2 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase TPR_2 PF07719.17 KFM61058.1 - 0.058 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4371 PF14291.6 KFM61060.1 - 0.024 14.3 0.1 0.027 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) Myb_DNA-binding PF00249.31 KFM61062.1 - 8.4e-15 54.7 14.2 5e-13 49.0 1.8 4.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM61062.1 - 2.1e-11 43.9 23.4 1.2e-07 31.8 3.5 4.5 2 1 2 4 4 4 2 Myb-like DNA-binding domain Tricorn_C1 PF14684.6 KFM61062.1 - 0.041 14.0 3.0 0.051 13.6 0.3 2.6 2 1 0 2 2 2 0 Tricorn protease C1 domain SLIDE PF09111.10 KFM61062.1 - 0.26 11.3 6.8 0.24 11.4 0.8 2.9 2 1 1 3 3 3 0 SLIDE Atg29_N PF18388.1 KFM61062.1 - 0.82 9.5 6.7 9.6 6.1 0.1 2.9 3 0 0 3 3 3 0 Atg29 N-terminal domain Ada3 PF10198.9 KFM61062.1 - 0.84 9.8 6.5 0.28 11.3 3.3 1.8 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 SANT_DAMP1_like PF16282.5 KFM61062.1 - 0.92 9.8 8.7 1 9.6 0.0 3.4 3 2 0 3 3 3 0 SANT/Myb-like domain of DAMP1 HTH_32 PF13565.6 KFM61062.1 - 2.2 9.0 4.5 1.8 9.2 0.5 2.7 2 1 1 3 3 3 0 Homeodomain-like domain Na_H_Exchanger PF00999.21 KFM61063.1 - 4.6e-73 246.2 30.7 3.8e-72 243.2 30.7 1.9 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family TMEM190 PF15431.6 KFM61063.1 - 0.0054 16.9 0.1 0.017 15.3 0.1 1.8 1 0 0 1 1 1 1 Transmembrane protein 190 DUF2427 PF10348.9 KFM61063.1 - 0.67 9.8 5.1 2.6 7.9 3.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF2537 PF10801.8 KFM61063.1 - 0.72 10.1 4.2 30 4.9 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2537) DUF2157 PF09925.9 KFM61063.1 - 1 9.1 8.5 0.1 12.4 0.3 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) LRR_8 PF13855.6 KFM61065.1 - 2.9e-18 65.4 3.0 1.3e-06 28.0 0.0 3.9 3 2 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFM61065.1 - 6.3e-10 39.2 7.2 0.0092 16.4 0.0 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM61065.1 - 6.3e-09 35.6 2.3 0.00044 19.8 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFM61065.1 - 3.4e-08 33.5 0.6 1.5e-05 24.9 0.2 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM61065.1 - 0.013 15.9 0.1 27 5.8 0.0 4.5 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KFM61065.1 - 0.015 15.3 3.5 7.7 6.9 0.3 4.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 KFM61066.1 - 5.5e-18 64.5 5.5 9.7e-11 41.3 1.6 2.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFM61066.1 - 1.2e-06 28.7 1.7 4e-05 23.9 0.1 2.7 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM61066.1 - 5.3e-06 26.4 8.1 4.2e-05 23.5 1.7 2.6 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM61066.1 - 3.2e-05 23.5 0.2 5.1e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat Phage_gp53 PF11246.8 KFM61068.1 - 0.025 14.2 0.0 0.077 12.7 0.0 1.7 2 0 0 2 2 2 0 Base plate wedge protein 53 CytochromB561_N PF09786.9 KFM61069.1 - 0.19 10.7 4.3 0.21 10.6 3.6 1.3 1 1 0 1 1 1 0 Cytochrome B561, N terminal Syja_N PF02383.18 KFM61070.1 - 2.1e-08 33.9 0.3 3.1e-08 33.3 0.1 1.4 2 0 0 2 2 2 1 SacI homology domain WYL PF13280.6 KFM61070.1 - 0.00036 20.6 0.0 0.00047 20.3 0.0 1.1 1 0 0 1 1 1 1 WYL domain PDZ_4 PF17816.1 KFM61070.1 - 0.062 13.7 0.3 0.13 12.7 0.2 1.7 1 1 0 1 1 1 0 PDZ domain Arc_trans_TRASH PF08394.10 KFM61070.1 - 0.094 13.1 0.2 0.27 11.6 0.2 1.8 1 0 0 1 1 1 0 Archaeal TRASH domain Ank_2 PF12796.7 KFM61071.1 - 2.6e-28 98.4 3.3 2.4e-08 34.4 0.0 6.4 4 3 2 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 KFM61071.1 - 3.7e-26 90.4 2.8 0.0042 17.5 0.0 11.2 10 1 1 11 11 11 7 Ankyrin repeat Ank_4 PF13637.6 KFM61071.1 - 3.1e-23 81.8 12.1 3.3e-07 30.7 0.1 9.0 6 2 5 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM61071.1 - 1.1e-22 77.6 12.5 0.0066 16.9 0.0 11.9 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 KFM61071.1 - 5.9e-15 55.1 15.0 0.091 13.1 0.0 10.6 9 2 3 12 12 12 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFM61071.1 - 4.4e-08 33.3 2.0 6.1e-08 32.9 0.2 2.3 2 0 0 2 2 2 1 SOCS box S1 PF00575.23 KFM61072.1 - 3.6e-34 116.9 17.4 2.3e-11 43.9 1.3 4.3 4 0 0 4 4 4 4 S1 RNA binding domain S1_2 PF13509.6 KFM61072.1 - 1.3e-12 47.6 1.4 1.1e-05 25.4 0.0 4.3 4 1 0 4 4 4 3 S1 domain RNase_II_C_S1 PF18614.1 KFM61072.1 - 6.7e-08 32.4 0.0 0.57 10.2 0.0 3.9 4 0 0 4 4 4 3 RNase II-type exonuclease C-terminal S1 domain AdoMet_MTase PF07757.13 KFM61072.1 - 4.2e-05 23.8 0.1 3.5 8.0 0.0 3.4 3 0 0 3 3 3 2 Predicted AdoMet-dependent methyltransferase TOBE_2 PF08402.10 KFM61072.1 - 0.00039 20.5 0.3 0.68 10.1 0.1 3.5 3 0 0 3 3 3 1 TOBE domain CsrA PF02599.16 KFM61072.1 - 0.00047 20.0 6.7 1.7 8.7 0.0 4.1 4 0 0 4 4 4 2 Global regulator protein family KH_6 PF15985.5 KFM61072.1 - 0.004 17.5 0.3 4.5 7.7 0.0 2.6 2 0 0 2 2 2 2 KH domain Ribosomal_L19 PF01245.20 KFM61072.1 - 0.011 15.6 3.1 14 5.7 0.1 4.1 4 0 0 4 4 4 0 Ribosomal protein L19 FN3_7 PF18447.1 KFM61072.1 - 0.038 14.3 2.1 4.4 7.7 0.2 3.2 3 0 0 3 3 3 0 Fibronectin type III domain Porphyrn_cat_1 PF18206.1 KFM61072.1 - 0.42 11.2 5.0 11 6.7 0.2 3.0 3 0 0 3 3 3 0 Porphyranase catalytic subdomain 1 Tex_N PF09371.10 KFM61073.1 - 5.5e-45 153.3 4.0 1e-44 152.4 4.0 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 KFM61073.1 - 1.5e-44 151.4 0.0 3.9e-44 150.1 0.0 1.8 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 KFM61073.1 - 6.1e-21 74.4 0.0 1.8e-20 72.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KFM61073.1 - 3.6e-09 36.6 0.0 1.4e-08 34.6 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_9 PF17674.1 KFM61073.1 - 3.1e-07 31.2 1.0 1.5e-06 29.0 0.0 2.8 3 0 0 3 3 3 1 HHH domain HHH_7 PF14635.6 KFM61073.1 - 3.5e-07 30.5 0.0 1e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_6 PF14579.6 KFM61073.1 - 0.072 13.4 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif Potassium_chann PF11404.8 KFM61073.1 - 0.68 9.8 3.0 3.3 7.6 3.0 2.2 1 0 0 1 1 1 0 Potassium voltage-gated channel PAP2_C PF14360.6 KFM61074.1 - 1.7e-27 95.7 12.7 1.7e-27 95.7 12.7 2.8 2 1 1 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 KFM61074.1 - 6.1e-06 26.0 8.9 6.1e-06 26.0 8.9 2.2 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFM61074.1 - 0.00017 21.4 16.2 0.00032 20.4 13.4 2.2 2 0 0 2 2 2 1 PAP2 superfamily RasGEF PF00617.19 KFM61075.1 - 4.1e-49 167.2 0.1 4.1e-49 167.2 0.1 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFM61075.1 - 8.2e-14 51.7 2.5 2.2e-12 47.1 0.9 3.2 2 1 0 2 2 2 1 RasGEF N-terminal motif PDZ PF00595.24 KFM61075.1 - 1.5e-12 47.7 0.0 2.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM61075.1 - 3.2e-11 42.9 0.0 7.4e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain RA PF00788.23 KFM61075.1 - 1.3e-07 32.1 0.0 4.2e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain cNMP_binding PF00027.29 KFM61075.1 - 0.00029 20.8 0.0 0.0008 19.4 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PDZ_2 PF13180.6 KFM61075.1 - 0.00058 20.1 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain LCE6A PF15858.5 KFM61075.1 - 0.72 10.6 5.8 0.44 11.3 0.6 3.3 3 0 0 3 3 3 0 Late cornified envelope protein 6A family DDE_3 PF13358.6 KFM61077.1 - 0.0059 16.4 0.1 1.3 8.8 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease HSR PF03172.13 KFM61078.1 - 0.086 13.0 0.1 0.097 12.8 0.1 1.0 1 0 0 1 1 1 0 HSR domain DUF4749 PF15936.5 KFM61079.1 - 3.8e-11 44.0 0.0 1.1e-10 42.5 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFM61079.1 - 9.8e-11 41.9 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM61079.1 - 1.7e-05 24.5 0.1 3.3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM61079.1 - 0.00024 21.4 0.0 0.00051 20.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain ORC6 PF05460.13 KFM61079.1 - 0.0046 16.3 1.6 0.0086 15.4 1.6 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Helicase_C_2 PF13307.6 KFM61082.1 - 1.8e-12 47.8 0.3 6e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain MFS_1 PF07690.16 KFM61083.1 - 1.6e-18 66.8 14.8 3.6e-18 65.6 14.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_L44 PF00935.19 KFM61085.1 - 1.1e-25 89.8 9.3 1.3e-25 89.7 9.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L44 Hyd_WA PF06462.12 KFM61087.1 - 1.8e-07 31.0 8.0 0.00028 20.8 0.7 3.9 4 0 0 4 4 4 2 Propeller CRIM PF16978.5 KFM61088.1 - 9.1e-30 103.7 0.0 1.9e-29 102.6 0.0 1.6 1 1 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1 PF05422.12 KFM61088.1 - 1.5e-20 74.2 3.4 1.1e-15 58.4 0.8 2.3 1 1 1 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) Ubiq_cyt_C_chap PF03981.12 KFM61088.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone SIN1_PH PF16979.5 KFM61089.1 - 1.2e-30 106.0 0.0 1.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology LIM PF00412.22 KFM61090.1 - 1.1e-12 48.0 0.2 1.6e-12 47.5 0.2 1.3 1 0 0 1 1 1 1 LIM domain Homeodomain PF00046.29 KFM61090.1 - 4e-05 23.4 0.9 5.6e-05 22.9 0.9 1.2 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc3_2 PF01498.18 KFM61092.1 - 5.1e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM61092.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM61092.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM61092.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM61092.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Fcf2 PF08698.11 KFM61093.1 - 3.9e-32 110.5 3.2 3.9e-32 110.5 3.2 2.7 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing LRR_8 PF13855.6 KFM61094.1 - 1.2e-54 181.9 80.6 1.7e-12 46.9 8.2 7.4 2 2 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFM61094.1 - 1.6e-27 95.1 58.6 3.6e-07 30.4 3.5 8.1 3 1 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM61094.1 - 4.9e-18 65.3 2.3 1.3e-06 28.4 0.0 3.3 2 1 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM61094.1 - 1.1e-14 54.3 21.5 0.00031 20.3 0.6 4.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFM61094.1 - 6e-06 26.1 52.5 0.8 10.5 0.3 12.6 11 2 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.6 KFM61094.1 - 0.0036 17.2 47.4 0.14 12.3 0.3 11.4 12 1 0 12 12 12 3 Leucine Rich repeat PI-TkoII_IV PF18714.1 KFM61094.1 - 0.57 9.6 3.5 7.4 6.0 0.0 2.7 2 1 0 2 2 2 0 DNA polymerase II intein Domain IV S4 PF01479.25 KFM61095.1 - 8.2e-11 41.5 0.0 1.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 S4 domain Stealth_CR1 PF17101.5 KFM61095.1 - 0.14 11.9 0.3 0.76 9.6 0.8 2.0 2 1 0 2 2 2 0 Stealth protein CR1, conserved region 1 Oxidored_molyb PF00174.19 KFM61096.1 - 7.2e-62 208.0 0.0 1.3e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KFM61096.1 - 1.4e-41 141.8 1.3 1.7e-41 141.4 0.3 1.7 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KFM61096.1 - 4.5e-14 52.4 0.0 8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 KFM61096.1 - 0.083 12.9 0.8 0.32 11.2 0.8 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat Abhydrolase_6 PF12697.7 KFM61097.1 - 3.2e-06 27.9 0.6 0.0047 17.6 0.1 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM61097.1 - 0.016 14.9 0.0 5.3 6.6 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold NPR2 PF06218.11 KFM61099.1 - 2.6e-79 267.1 12.0 3.8e-65 220.4 11.4 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 ShK PF01549.24 KFM61099.1 - 0.12 12.9 0.9 0.33 11.5 0.9 1.8 1 0 0 1 1 1 0 ShK domain-like CaM-KIIN PF15170.6 KFM61099.1 - 0.16 12.1 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor Macro PF01661.21 KFM61100.1 - 3.4e-40 136.7 0.1 5.9e-40 136.0 0.1 1.4 1 0 0 1 1 1 1 Macro domain Na_H_Exchanger PF00999.21 KFM61101.1 - 2.7e-32 112.0 28.5 2.7e-32 112.0 28.5 1.8 1 1 1 2 2 2 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 KFM61102.1 - 1.1e-32 113.2 30.1 1.8e-32 112.6 30.1 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_transf_21 PF13506.6 KFM61103.1 - 1.7e-51 174.2 0.0 2.4e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KFM61103.1 - 5.4e-18 65.7 0.0 8.2e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KFM61103.1 - 1.5e-09 38.0 4.9 2.8e-09 37.2 4.9 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KFM61103.1 - 0.00018 21.4 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Spaetzle PF16077.5 KFM61104.1 - 5.2e-10 39.7 0.7 5.9e-10 39.6 0.7 1.0 1 0 0 1 1 1 1 Spaetzle Jun PF03957.13 KFM61105.1 - 2.3e-28 99.7 4.8 4.8e-28 98.6 4.8 1.5 1 1 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.21 KFM61105.1 - 5.3e-17 61.7 15.3 5.3e-17 61.7 15.3 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFM61105.1 - 7.1e-09 35.6 12.3 3.1e-08 33.6 12.3 2.0 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFM61105.1 - 1.2e-06 28.9 9.0 1.2e-06 28.9 9.0 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor YabA PF06156.13 KFM61105.1 - 0.037 14.7 5.0 0.46 11.1 2.8 2.4 2 0 0 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 KFM61105.1 - 0.17 12.3 3.0 0.36 11.2 3.0 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 KFM61105.1 - 0.4 10.0 5.9 0.035 13.4 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TSC22 PF01166.18 KFM61105.1 - 1.3 9.4 6.7 0.74 10.2 1.0 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family DivIC PF04977.15 KFM61105.1 - 1.6 8.5 9.3 0.099 12.4 3.3 2.0 2 1 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 KFM61105.1 - 1.9 9.0 11.7 0.13 12.8 5.3 2.2 2 0 0 2 2 2 0 Cell division protein ZapB XhlA PF10779.9 KFM61105.1 - 3.6 7.9 6.3 1.6 9.0 2.3 2.3 2 0 0 2 2 2 0 Haemolysin XhlA zf-H2C2_2 PF13465.6 KFM61106.1 - 3.2e-85 277.1 92.1 1.1e-09 38.2 0.3 13.8 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM61106.1 - 1.9e-61 201.3 116.8 3e-07 30.5 1.1 13.2 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61106.1 - 6.5e-46 151.0 104.9 0.00016 22.2 0.7 13.2 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM61106.1 - 6.2e-27 93.2 97.0 0.0043 17.4 0.8 13.3 13 0 0 13 13 13 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM61106.1 - 9.9e-23 79.9 71.6 0.02 15.2 2.7 13.4 11 2 2 13 13 13 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM61106.1 - 2.1e-22 78.6 90.7 0.0058 16.6 0.6 13.7 13 1 0 13 13 13 9 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM61106.1 - 2.6e-08 33.6 30.3 2.3 8.2 0.0 11.3 11 0 0 11 11 11 1 zinc-finger of a C2HC-type BolA PF01722.18 KFM61106.1 - 0.00013 22.1 14.6 1 9.7 0.0 6.9 3 2 3 6 6 6 1 BolA-like protein zf-H2C2_5 PF13909.6 KFM61106.1 - 0.00014 21.5 94.4 0.0002 21.0 0.9 13.2 13 0 0 13 13 13 5 C2H2-type zinc-finger domain GAGA PF09237.11 KFM61106.1 - 0.00016 21.4 22.2 1.2 9.0 0.2 7.8 2 2 6 9 9 9 2 GAGA factor zinc_ribbon_15 PF17032.5 KFM61106.1 - 0.0003 21.5 48.0 5.4 7.8 0.7 7.1 2 1 5 7 7 7 2 zinc-ribbon family ADK_lid PF05191.14 KFM61106.1 - 0.0015 18.5 40.9 0.29 11.1 1.5 8.8 6 2 2 8 8 8 3 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM61106.1 - 0.0016 18.7 86.3 0.83 10.0 2.1 11.6 1 1 8 10 10 10 3 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM61106.1 - 0.0023 17.5 45.7 1.1 8.9 0.2 11.5 12 1 0 12 12 12 2 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFM61106.1 - 0.013 15.3 0.1 0.013 15.3 0.1 9.6 12 0 0 12 12 10 0 zinc-finger C2H2-type DUF4825 PF16107.5 KFM61106.1 - 0.014 15.5 0.0 2.4 8.4 0.0 3.8 3 1 3 6 6 6 0 Domain of unknown function (DUF4825) zf-RRPl_C4 PF17026.5 KFM61106.1 - 0.015 15.4 5.0 0.015 15.4 5.0 6.1 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM61106.1 - 0.49 10.6 46.6 18 5.5 0.1 11.6 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.10 KFM61106.1 - 0.63 10.2 40.7 1.1 9.5 1.1 8.0 6 3 3 9 9 9 0 Zinc ribbon domain Flag1_repress PF03614.13 KFM61106.1 - 1.5 8.6 5.9 25 4.6 0.1 3.5 2 2 1 3 3 3 0 Repressor of phase-1 flagellin AMPKBI PF04739.15 KFM61106.1 - 3.3 8.1 6.6 1.5 9.1 2.0 2.8 2 1 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain Phosducin PF02114.16 KFM61107.1 - 3.2e-18 65.6 0.4 4.1e-18 65.3 0.4 1.1 1 0 0 1 1 1 1 Phosducin Tugs PF17840.1 KFM61107.1 - 0.11 12.7 0.3 0.23 11.7 0.3 1.5 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain V-set PF07686.17 KFM61108.1 - 6.8e-07 29.4 0.0 7.9e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM61108.1 - 0.00018 21.8 0.0 0.00043 20.6 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM61108.1 - 0.0017 18.9 0.0 0.0026 18.3 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM61108.1 - 0.0064 16.5 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM61108.1 - 0.012 15.8 0.0 0.014 15.6 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFM61108.1 - 0.057 13.5 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFM61108.1 - 0.075 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain PDEase_I PF00233.19 KFM61112.1 - 3.7e-21 75.9 0.1 4e-21 75.8 0.1 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Yop-YscD_ppl PF16693.5 KFM61114.1 - 0.028 13.9 0.1 0.041 13.3 0.1 1.4 1 1 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain p450 PF00067.22 KFM61115.1 - 1.6e-35 122.8 0.1 1.7e-35 122.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM61116.1 - 3.4e-63 214.0 0.1 4.1e-63 213.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CRM1_repeat_2 PF18784.1 KFM61116.1 - 0.11 12.2 0.3 3.5 7.3 0.3 2.4 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 Uteroglobin PF01099.17 KFM61116.1 - 0.36 11.2 1.8 14 6.1 0.1 3.0 3 0 0 3 3 3 0 Uteroglobin family p450 PF00067.22 KFM61117.1 - 1.2e-30 106.7 0.1 1.3e-30 106.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aconitase PF00330.20 KFM61117.1 - 0.048 12.6 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Exo84_C PF16528.5 KFM61118.1 - 1.6e-46 158.8 0.2 1.6e-46 158.8 0.2 2.4 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KFM61118.1 - 3.6e-16 59.0 1.4 1e-15 57.6 1.4 1.8 1 0 0 1 1 1 1 Vps51/Vps67 PH PF00169.29 KFM61118.1 - 2.2e-05 24.9 0.0 6.7e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 PH domain COG2 PF06148.11 KFM61118.1 - 0.029 14.5 3.5 0.13 12.4 3.5 2.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 NPF PF16601.5 KFM61118.1 - 0.08 13.4 0.9 0.17 12.4 0.9 1.5 1 0 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif DUF4371 PF14291.6 KFM61119.1 - 2.7e-30 105.7 0.5 5.3e-30 104.8 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM61119.1 - 9.7e-10 38.1 0.2 3.4e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM61119.1 - 0.037 13.0 7.6 0.05 12.6 0.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MAT1 PF06391.13 KFM61119.1 - 2.3 8.0 7.7 2.4 8.0 2.0 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4355 PF14265.6 KFM61119.1 - 3.3 8.0 5.7 3.7 7.8 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Exonuc_VII_L PF02601.15 KFM61119.1 - 4 6.9 7.1 6.3 6.3 1.2 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA PF00004.29 KFM61120.1 - 1.6e-96 319.8 0.0 6.6e-47 159.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM61120.1 - 3.2e-26 90.9 4.5 1.1e-13 50.7 0.8 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KFM61120.1 - 6.8e-21 74.2 0.3 2e-20 72.7 0.3 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KFM61120.1 - 1.1e-13 51.2 0.0 2.1e-05 24.3 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM61120.1 - 1.9e-13 51.1 0.7 7.7e-05 23.1 0.1 4.3 3 2 1 4 4 3 2 AAA ATPase domain CDC48_2 PF02933.17 KFM61120.1 - 6.1e-12 45.1 0.0 1.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 KFM61120.1 - 6.5e-11 42.6 0.0 4e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KFM61120.1 - 2.5e-10 40.8 0.0 4.1e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFM61120.1 - 3.3e-10 40.1 0.1 8.9e-05 22.5 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM61120.1 - 1.2e-09 38.6 0.2 0.015 15.6 0.2 4.1 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 KFM61120.1 - 8.8e-09 35.0 0.0 0.0012 18.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 KFM61120.1 - 4.9e-08 33.6 0.0 0.012 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFM61120.1 - 2.3e-07 31.1 0.0 0.0059 17.0 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KFM61120.1 - 4.7e-07 29.4 0.1 0.025 14.0 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 KFM61120.1 - 8.3e-07 28.9 0.4 4.9e-05 23.3 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KFM61120.1 - 9.3e-07 28.7 0.0 0.058 13.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KFM61120.1 - 1.1e-06 28.7 0.0 0.062 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KFM61120.1 - 1.4e-06 28.6 0.4 0.15 12.3 0.0 3.5 3 1 0 3 3 3 2 AAA domain ATPase PF06745.13 KFM61120.1 - 2.7e-06 26.9 0.1 0.18 11.1 0.0 3.4 3 0 0 3 3 3 2 KaiC Parvo_NS1 PF01057.17 KFM61120.1 - 3.1e-06 26.5 0.1 0.034 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 KFM61120.1 - 4e-06 26.8 0.0 0.057 13.3 0.0 3.2 3 0 0 3 3 3 2 Bacterial dnaA protein ATPase_2 PF01637.18 KFM61120.1 - 1e-05 25.6 0.4 0.27 11.1 0.0 3.8 4 1 0 4 4 3 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KFM61120.1 - 1.3e-05 24.8 0.0 0.12 11.9 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 KFM61120.1 - 1.6e-05 25.4 0.0 0.02 15.4 0.0 3.3 2 1 0 2 2 2 1 ABC transporter DUF815 PF05673.13 KFM61120.1 - 1.7e-05 24.1 0.0 0.017 14.3 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFM61120.1 - 2.9e-05 23.9 0.0 0.061 13.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.6 KFM61120.1 - 3e-05 24.5 0.1 0.98 9.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.6 KFM61120.1 - 6.2e-05 22.7 2.2 2.9 7.4 0.0 3.7 2 2 1 4 4 4 2 AAA domain TsaE PF02367.17 KFM61120.1 - 8.7e-05 22.5 0.0 0.37 10.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KFM61120.1 - 0.00012 21.8 0.0 0.46 10.2 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.12 KFM61120.1 - 0.00017 21.6 0.2 0.2 11.6 0.0 3.2 3 1 0 3 3 3 1 NACHT domain Viral_helicase1 PF01443.18 KFM61120.1 - 0.00036 20.4 0.0 0.0049 16.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KFM61120.1 - 0.00037 19.8 0.0 0.25 10.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 KFM61120.1 - 0.00053 19.3 0.0 0.67 9.2 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.11 KFM61120.1 - 0.00074 19.4 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KFM61120.1 - 0.00091 18.6 0.0 0.33 10.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFM61120.1 - 0.0012 18.9 0.0 0.092 12.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFM61120.1 - 0.0014 18.2 0.2 1.7 8.0 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.6 KFM61120.1 - 0.0018 18.4 0.0 3.1 7.9 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 KFM61120.1 - 0.0019 18.0 0.3 2.3 7.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KFM61120.1 - 0.0041 17.1 0.0 0.99 9.3 0.0 2.8 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_19 PF13245.6 KFM61120.1 - 0.005 17.2 0.6 2.8 8.3 0.2 3.0 2 1 1 3 3 2 1 AAA domain AAA_30 PF13604.6 KFM61120.1 - 0.018 14.8 0.2 2.8 7.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFM61120.1 - 0.034 14.1 0.4 5.2 6.9 0.0 3.1 3 0 0 3 3 3 0 NTPase Cytidylate_kin PF02224.18 KFM61120.1 - 0.039 13.7 0.0 9.5 5.9 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 KFM61120.1 - 0.046 13.8 0.2 8.1 6.5 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase UFD1 PF03152.14 KFM61120.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Zot PF05707.12 KFM61120.1 - 0.11 12.1 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DNA_ligase_A_C PF04679.15 KFM61120.1 - 0.15 12.7 0.1 0.88 10.2 0.0 2.4 2 1 0 2 2 1 0 ATP dependent DNA ligase C terminal region AAA_23 PF13476.6 KFM61120.1 - 2 8.9 4.6 21 5.5 0.0 3.3 3 1 0 3 3 2 0 AAA domain HTH_48 PF17906.1 KFM61121.1 - 0.034 14.3 0.1 0.068 13.3 0.1 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase FA_desaturase PF00487.24 KFM61122.1 - 2.9e-06 27.3 6.2 2.9e-06 27.3 6.2 2.0 1 1 1 2 2 2 2 Fatty acid desaturase CPBP PF02517.16 KFM61122.1 - 0.026 14.9 0.3 0.049 14.0 0.3 1.4 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease DAO PF01266.24 KFM61123.1 - 1.1e-26 94.3 0.0 1.2e-26 94.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM61123.1 - 1.9e-05 23.9 0.1 9.6e-05 21.6 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFM61123.1 - 0.00015 21.1 0.2 0.045 13.0 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM61123.1 - 0.0034 17.6 0.0 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFM61123.1 - 0.0057 17.2 0.0 0.76 10.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFM61123.1 - 0.0065 15.8 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KFM61123.1 - 0.018 13.8 0.0 0.23 10.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KFM61123.1 - 0.029 13.4 0.1 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFM61123.1 - 0.039 13.2 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KFM61123.1 - 0.064 12.5 0.3 0.14 11.4 0.3 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KFM61123.1 - 0.15 12.0 1.6 0.33 10.8 0.0 2.1 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMN_dh PF01070.18 KFM61124.1 - 4.1e-125 417.4 0.0 4.6e-125 417.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFM61124.1 - 1.2e-06 27.8 0.2 4.2e-06 26.0 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFM61124.1 - 0.0017 17.6 0.2 0.0027 16.9 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glycos_transf_1 PF00534.20 KFM61124.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 DHO_dh PF01180.21 KFM61124.1 - 0.26 10.5 0.4 13 4.9 0.0 2.3 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase Aldedh PF00171.22 KFM61125.1 - 3.3e-130 434.7 0.0 3.7e-130 434.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Metallophos PF00149.28 KFM61128.1 - 1.2e-39 136.9 0.1 1.7e-39 136.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFM61128.1 - 0.00047 20.6 1.6 0.0011 19.4 0.7 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KFM61128.1 - 0.17 12.0 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PPP1R35_C PF15503.6 KFM61132.1 - 0.41 10.4 2.4 1.1 9.1 0.2 2.3 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus WD40 PF00400.32 KFM61134.1 - 2.2e-20 72.6 11.1 1.5e-05 25.6 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM61134.1 - 1.2e-09 38.3 0.3 0.013 15.8 0.0 5.4 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 KFM61134.1 - 0.022 14.3 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region XTBD PF11952.8 KFM61135.1 - 0.00075 19.2 0.1 0.37 10.6 0.0 3.6 3 1 0 3 3 3 1 XRN-Two Binding Domain, XTBD RINT1_TIP1 PF04437.13 KFM61135.1 - 0.049 12.5 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 RINT-1 / TIP-1 family LRR_9 PF14580.6 KFM61135.1 - 0.055 13.0 0.4 0.69 9.4 0.2 2.6 2 0 0 2 2 2 0 Leucine-rich repeat LRR_4 PF12799.7 KFM61135.1 - 1.8 9.1 18.8 14 6.3 0.9 6.9 5 2 4 9 9 9 0 Leucine Rich repeats (2 copies) zf-U1 PF06220.12 KFM61136.1 - 1.2e-21 76.2 9.8 1.6e-21 75.8 9.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 KFM61136.1 - 0.44 11.0 4.8 4.8 7.7 4.8 2.2 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM61136.1 - 2 8.8 10.7 23 5.4 10.7 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding BRE PF06113.12 KFM61137.1 - 1.2e-95 320.0 0.1 1.5e-95 319.7 0.1 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Dus PF01207.17 KFM61138.1 - 3.8e-19 68.9 0.0 4.1e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Dus PF01207.17 KFM61139.1 - 3.7e-31 108.4 0.2 2.2e-30 105.8 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) tRNA_m1G_MT PF01746.21 KFM61139.1 - 2e-20 73.3 0.0 4e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase His_biosynth PF00977.21 KFM61139.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 KFM61139.1 - 0.0071 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 KFM61139.1 - 0.031 13.7 0.1 0.084 12.3 0.0 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase ThiG PF05690.14 KFM61139.1 - 0.082 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG AP-5_subunit_s1 PF15001.6 KFM61139.1 - 0.13 12.3 1.7 0.26 11.3 1.4 1.7 1 1 0 1 1 1 0 AP-5 complex subunit sigma-1 SOR_SNZ PF01680.17 KFM61139.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 SOR/SNZ family FMN_dh PF01070.18 KFM61139.1 - 0.19 10.7 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Sushi PF00084.20 KFM61140.1 - 2.1e-49 166.0 14.7 5.8e-10 39.6 0.1 5.6 5 0 0 5 5 5 5 Sushi repeat (SCR repeat) HRM PF02793.22 KFM61140.1 - 2.8e-06 27.5 18.3 0.035 14.4 0.1 5.6 5 1 0 5 5 5 3 Hormone receptor domain Ig_3 PF13927.6 KFM61140.1 - 0.0025 18.3 1.0 0.079 13.6 0.1 3.6 3 1 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 KFM61140.1 - 0.0032 17.5 0.1 0.012 15.7 0.1 2.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain VERL PF11386.8 KFM61140.1 - 0.3 11.3 1.6 5.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Vitelline envelope receptor for lysin Pelovaterin PF17859.1 KFM61140.1 - 0.4 11.0 3.7 0.57 10.5 0.1 2.9 3 0 0 3 3 3 0 Pelovaterin cEGF PF12662.7 KFM61140.1 - 1.5 8.8 4.2 25 4.9 0.0 4.3 5 0 0 5 5 5 0 Complement Clr-like EGF-like EF1_GNE PF00736.19 KFM61141.1 - 4.1e-34 116.6 2.5 4.1e-34 116.6 2.5 2.0 2 0 0 2 2 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFM61141.1 - 3.3e-07 30.6 3.7 3.3e-07 30.6 3.7 3.2 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region DUF4446 PF14584.6 KFM61141.1 - 0.00021 21.3 0.7 0.00021 21.3 0.7 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF4446) Tropomyosin PF00261.20 KFM61141.1 - 0.0073 15.7 2.7 0.0073 15.7 2.7 2.9 2 2 0 3 3 3 1 Tropomyosin DUF2859 PF11072.8 KFM61141.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) Fzo_mitofusin PF04799.13 KFM61141.1 - 0.016 14.8 2.9 0.067 12.7 2.1 2.2 2 0 0 2 2 2 0 fzo-like conserved region Sec34 PF04136.15 KFM61141.1 - 0.018 14.9 2.3 0.046 13.6 2.3 1.7 1 0 0 1 1 1 0 Sec34-like family MinC_N PF05209.13 KFM61141.1 - 0.021 14.8 0.0 0.083 12.8 0.0 2.0 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Taxilin PF09728.9 KFM61141.1 - 0.028 13.6 15.8 0.12 11.6 8.4 2.8 2 1 0 2 2 2 0 Myosin-like coiled-coil protein GvpK PF05121.12 KFM61141.1 - 0.15 12.1 1.4 1.6 8.8 0.3 2.7 3 0 0 3 3 3 0 Gas vesicle protein K FUSC PF04632.12 KFM61141.1 - 0.25 9.9 0.1 0.34 9.4 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cor1 PF04803.12 KFM61141.1 - 0.48 10.6 7.8 0.059 13.6 2.7 2.0 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Cluap1 PF10234.9 KFM61141.1 - 0.51 9.7 11.9 0.029 13.8 6.2 1.6 2 0 0 2 2 2 0 Clusterin-associated protein-1 Baculo_PEP_C PF04513.12 KFM61141.1 - 0.52 10.3 5.9 0.27 11.3 1.8 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 KFM61141.1 - 0.67 9.2 7.4 0.076 12.3 3.2 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Herpes_BLRF2 PF05812.12 KFM61141.1 - 0.8 9.9 7.0 0.093 12.9 0.7 2.4 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein JIP_LZII PF16471.5 KFM61141.1 - 3.7 7.8 9.0 0.23 11.6 2.7 2.4 2 0 0 2 2 1 0 JNK-interacting protein leucine zipper II TMPIT PF07851.13 KFM61141.1 - 10 5.3 6.9 2.5 7.3 1.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein RFX_DNA_binding PF02257.15 KFM61142.1 - 2e-35 121.2 0.1 4e-35 120.3 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFM61142.1 - 0.087 13.3 0.4 0.19 12.3 0.0 1.8 2 0 0 2 2 2 0 Poxvirus D5 protein-like Laminin_EGF PF00053.24 KFM61145.1 - 1.4e-23 82.7 130.6 0.0044 17.1 15.5 8.0 2 2 6 8 8 8 6 Laminin EGF domain EGF_2 PF07974.13 KFM61145.1 - 4.6e-09 36.5 180.3 0.001 19.4 13.3 12.7 11 3 1 12 12 10 7 EGF-like domain hEGF PF12661.7 KFM61145.1 - 1.9e-05 25.1 36.6 0.00012 22.5 6.7 12.5 11 4 4 15 15 13 5 Human growth factor-like EGF Syndecan PF01034.20 KFM61145.1 - 0.00021 21.1 0.1 0.00037 20.3 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain DSL PF01414.19 KFM61145.1 - 0.0058 16.9 153.9 0.033 14.4 16.0 7.7 8 0 0 8 8 8 5 Delta serrate ligand RIFIN PF02009.16 KFM61145.1 - 0.0084 16.0 0.6 0.017 15.1 0.6 1.4 1 0 0 1 1 1 1 Rifin SKG6 PF08693.10 KFM61145.1 - 0.011 15.2 2.7 0.018 14.4 2.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF PF00008.27 KFM61145.1 - 0.025 14.9 28.3 0.031 14.6 8.8 11.7 12 1 1 13 13 12 0 EGF-like domain TMEM154 PF15102.6 KFM61145.1 - 0.047 13.6 0.1 0.091 12.7 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 KFM61145.1 - 0.096 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4804 PF16062.5 KFM61145.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) EphA2_TM PF14575.6 KFM61145.1 - 0.13 13.1 0.0 0.35 11.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain KH_1 PF00013.29 KFM61148.1 - 0.015 15.1 0.3 0.022 14.6 0.3 1.3 1 0 0 1 1 1 0 KH domain Ras PF00071.22 KFM61149.1 - 1.8e-67 226.0 0.8 2.2e-67 225.7 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM61149.1 - 2.8e-36 124.4 0.3 5.6e-36 123.4 0.3 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM61149.1 - 1.7e-17 63.4 0.5 2.2e-17 63.0 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM61149.1 - 1.2e-06 28.1 0.6 1.5e-06 27.8 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM61149.1 - 1.8e-05 24.3 0.2 2.8e-05 23.6 0.2 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFM61149.1 - 0.00066 19.3 0.5 0.0012 18.4 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM61149.1 - 0.00093 19.3 0.1 0.0019 18.2 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM61149.1 - 0.0011 18.9 0.5 0.96 9.3 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase Septin PF00735.18 KFM61149.1 - 0.018 14.4 1.1 0.083 12.2 0.1 2.1 2 0 0 2 2 2 0 Septin DUF3963 PF13124.6 KFM61149.1 - 0.027 14.4 0.4 0.058 13.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AFT PF08731.11 KFM61149.1 - 0.036 14.5 2.1 0.086 13.2 2.1 1.7 1 1 0 1 1 1 0 Transcription factor AFT AAA_7 PF12775.7 KFM61149.1 - 0.057 12.9 0.5 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KFM61149.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_S21 PF01165.20 KFM61150.1 - 8.5e-16 57.4 0.3 1.7e-15 56.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S21 Glyco_tranf_2_4 PF13704.6 KFM61150.1 - 0.12 12.9 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 Sushi PF00084.20 KFM61151.1 - 2.9e-06 27.8 0.1 3.5e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) VWA PF00092.28 KFM61152.1 - 3.1e-13 50.3 0.0 4.2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Sushi PF00084.20 KFM61152.1 - 2.2e-11 44.2 0.5 2.2e-11 44.2 0.5 2.2 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) VWA_2 PF13519.6 KFM61152.1 - 2.2e-05 25.1 0.0 3.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain ABC_transp_aux PF09822.9 KFM61153.1 - 0.001 18.6 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 KFM61153.1 - 0.012 14.5 0.0 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta Pkinase PF00069.25 KFM61154.1 - 7.1e-42 143.6 0.0 8.3e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM61154.1 - 3.4e-29 101.9 0.0 4.1e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM61154.1 - 8e-05 22.1 0.0 8.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM61154.1 - 0.00015 20.8 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFM61154.1 - 0.0042 16.2 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KFM61154.1 - 0.0047 15.8 0.0 0.006 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KFM61154.1 - 0.052 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KFM61155.1 - 1.4e-06 27.8 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM61155.1 - 0.00026 20.3 0.0 0.00031 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.22 KFM61156.1 - 6e-35 118.9 0.8 2e-16 59.6 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM61156.1 - 0.00019 21.5 0.1 0.018 15.1 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif RRM_9 PF18444.1 KFM61156.1 - 0.0049 16.7 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif Transformer PF06495.11 KFM61156.1 - 0.061 13.4 24.2 0.13 12.4 24.2 1.5 1 0 0 1 1 1 0 Fruit fly transformer protein DUF3925 PF13063.6 KFM61158.1 - 0.049 13.8 0.8 0.078 13.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Snf7 PF03357.21 KFM61159.1 - 2.9e-17 62.8 20.8 2.9e-17 62.8 20.8 1.3 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.14 KFM61159.1 - 8.9e-05 22.5 8.9 0.00012 22.0 8.9 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 KFM61159.1 - 0.0028 17.3 0.2 0.006 16.2 0.2 1.5 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase DUF3447 PF11929.8 KFM61159.1 - 0.075 13.0 0.9 0.84 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) UCH PF00443.29 KFM61159.1 - 0.44 10.0 4.9 0.56 9.6 4.9 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF4363 PF14276.6 KFM61159.1 - 0.61 10.2 7.3 0.54 10.4 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) YusW PF14039.6 KFM61159.1 - 8.6 6.9 9.6 3 8.4 2.5 2.6 1 1 1 2 2 2 0 YusW-like protein Dfp1_Him1_M PF08630.10 KFM61159.1 - 8.9 6.5 8.7 5.6 7.2 2.0 2.3 2 1 0 2 2 2 0 Dfp1/Him1, central region FlaG PF03646.15 KFM61159.1 - 8.9 6.5 13.2 1.7 8.8 2.4 2.4 2 0 0 2 2 2 0 FlaG protein Pkinase_Tyr PF07714.17 KFM61163.1 - 3.8e-99 331.2 0.0 4.6e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM61163.1 - 8.9e-49 166.2 0.0 1.2e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KFM61163.1 - 0.00025 20.1 0.1 0.00065 18.7 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM61163.1 - 0.0026 17.7 0.1 0.024 14.6 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM61163.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-RING_2 PF13639.6 KFM61165.1 - 3.3e-10 40.1 5.9 9.3e-10 38.7 5.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM61165.1 - 8.1e-08 32.0 6.4 8.1e-08 32.0 6.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM61165.1 - 2.2e-07 30.6 6.8 8.8e-07 28.7 6.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM61165.1 - 2.6e-07 30.5 6.7 5.4e-07 29.5 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM61165.1 - 5e-07 29.6 3.2 1.3e-06 28.3 3.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM61165.1 - 8.6e-07 28.7 5.5 2.3e-06 27.4 5.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM61165.1 - 4.1e-06 26.6 7.2 4.2e-05 23.3 7.2 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFM61165.1 - 0.00011 21.9 4.8 0.00011 21.9 4.8 2.1 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFM61165.1 - 0.00048 20.3 4.4 0.00048 20.3 4.4 2.0 2 2 0 2 2 2 1 RING-H2 zinc finger domain zf-UDP PF14569.6 KFM61165.1 - 0.0018 18.3 6.2 0.002 18.2 4.4 1.9 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 KFM61165.1 - 0.012 15.7 4.1 0.012 15.7 4.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFM61165.1 - 0.024 14.7 1.4 0.058 13.4 1.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KFM61165.1 - 0.029 14.4 4.9 0.075 13.1 4.9 1.7 1 0 0 1 1 1 0 Double zinc ribbon DUF1272 PF06906.11 KFM61165.1 - 0.77 9.9 10.1 0.17 12.0 5.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.12 KFM61165.1 - 0.77 9.8 7.4 2.5 8.2 7.4 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-RING_10 PF16685.5 KFM61165.1 - 1.3 9.2 8.1 3.4 7.9 8.1 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 FANCL_C PF11793.8 KFM61165.1 - 3.7 7.8 9.9 25 5.1 7.0 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain DUF89 PF01937.19 KFM61167.1 - 2.3e-30 105.8 0.1 2.8e-30 105.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Fumble PF03630.14 KFM61168.1 - 1.1e-133 445.5 0.1 1.3e-133 445.3 0.1 1.0 1 0 0 1 1 1 1 Fumble CBM_14 PF01607.24 KFM61170.1 - 1.3e-12 47.7 6.2 2.4e-12 46.8 6.2 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Baculo_VP91_N PF08475.10 KFM61170.1 - 0.047 13.4 0.4 0.077 12.7 0.4 1.3 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Pkinase PF00069.25 KFM61171.1 - 5.4e-29 101.4 0.0 6.1e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM61171.1 - 8.5e-13 48.2 0.0 9.1e-13 48.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM61171.1 - 0.00011 21.7 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM61171.1 - 0.00011 22.2 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFM61171.1 - 0.0096 14.9 0.1 0.011 14.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 KFM61171.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KFM61171.1 - 0.029 13.1 0.0 0.037 12.8 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KFM61171.1 - 0.095 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KFM61171.1 - 0.23 11.0 0.0 0.29 10.6 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 KFM61172.1 - 0.03 13.7 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain SSrecog PF03531.14 KFM61172.1 - 0.046 13.6 0.2 0.11 12.4 0.2 1.7 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) Methyltransf_34 PF11312.8 KFM61173.1 - 2.6e-05 23.6 0.0 5.4e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Putative SAM-dependent methyltransferase DDE_Tnp_1_7 PF13843.6 KFM61174.1 - 1.3e-20 74.1 0.0 1.4e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 zf-GRF PF06839.12 KFM61177.1 - 2.1e-08 34.1 1.5 4.3e-08 33.1 1.5 1.5 1 0 0 1 1 1 1 GRF zinc finger EMC3_TMCO1 PF01956.16 KFM61180.1 - 3.8e-33 114.6 1.8 3.8e-33 114.6 1.8 1.6 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like Y_phosphatase PF00102.27 KFM61181.1 - 3.5e-23 82.4 0.0 3.8e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM61181.1 - 0.00042 20.3 0.1 0.0043 17.1 0.0 1.8 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFM61182.1 - 2.4e-62 210.6 0.3 1.1e-34 120.0 1.0 2.0 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM61182.1 - 0.002 18.2 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM61182.1 - 0.0059 16.7 0.0 0.034 14.3 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate APAF1_C PF17908.1 KFM61182.1 - 0.013 15.5 1.4 0.02 14.9 0.3 1.8 2 0 0 2 2 2 0 APAF-1 helical domain DSPc PF00782.20 KFM61182.1 - 0.018 14.9 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain fn3 PF00041.21 KFM61185.1 - 2.4e-08 34.2 0.4 4.2e-08 33.4 0.4 1.4 1 1 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM61185.1 - 0.083 13.5 0.9 0.11 13.0 0.9 1.2 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KFM61186.1 - 7.2e-06 26.3 0.0 9.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Fibronectin type III domain p450 PF00067.22 KFM61187.1 - 4.3e-74 249.9 3.4 4.8e-74 249.8 3.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM61188.1 - 9.4e-95 318.0 1.0 1.2e-94 317.6 1.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IGF2_C PF08365.11 KFM61190.1 - 0.068 13.2 0.1 0.068 13.2 0.1 1.2 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide TPR_2 PF07719.17 KFM61191.1 - 1.2e-14 53.1 2.7 0.0012 18.8 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM61191.1 - 2.3e-10 39.8 1.9 0.018 14.8 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM61191.1 - 4.9e-10 39.4 3.7 0.17 12.7 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM61191.1 - 7.7e-07 28.8 0.6 1.3 9.4 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM61191.1 - 8.9e-07 28.5 3.1 0.00019 21.1 0.0 4.1 3 1 1 4 4 4 1 TPR repeat TPR_12 PF13424.6 KFM61191.1 - 1e-06 28.9 5.3 0.24 11.7 0.8 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM61191.1 - 3.3e-06 26.8 2.2 1.6 8.7 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM61191.1 - 5e-06 26.2 6.0 0.017 15.1 0.0 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM61191.1 - 8.9e-06 26.1 7.0 0.27 11.8 0.0 3.7 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM61191.1 - 1.3e-05 25.7 7.8 0.034 14.8 1.3 4.0 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM61191.1 - 2e-05 24.6 0.0 0.0029 17.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 KFM61191.1 - 0.0063 16.6 0.5 0.24 11.5 0.1 2.9 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_9 PF13371.6 KFM61191.1 - 0.0096 16.1 3.1 0.067 13.3 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat IlvB_leader PF08049.11 KFM61191.1 - 0.065 13.2 1.3 0.16 11.9 1.3 1.7 1 0 0 1 1 1 0 IlvB leader peptide BTAD PF03704.17 KFM61191.1 - 0.075 13.5 2.7 10 6.6 0.9 3.3 1 1 2 3 3 3 0 Bacterial transcriptional activator domain DUF4027 PF13219.6 KFM61191.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) TPR_4 PF07721.14 KFM61191.1 - 0.66 10.8 7.7 17 6.4 0.2 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM61192.1 - 2.2e-113 370.7 90.6 5.3e-14 52.3 0.8 12.3 11 1 1 12 12 12 11 Tetratricopeptide repeat TPR_7 PF13176.6 KFM61192.1 - 5.6e-101 323.4 63.7 1.6e-06 27.8 0.0 21.6 21 0 0 21 21 21 19 Tetratricopeptide repeat TPR_1 PF00515.28 KFM61192.1 - 1.2e-81 265.5 72.9 5.6e-05 22.8 0.4 21.6 22 0 0 22 22 22 20 Tetratricopeptide repeat CHAT PF12770.7 KFM61192.1 - 5.2e-76 255.8 1.0 1e-75 254.8 1.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_8 PF13181.6 KFM61192.1 - 5.2e-56 182.2 47.9 0.00093 19.2 0.1 20.9 22 0 0 22 22 21 12 Tetratricopeptide repeat TPR_2 PF07719.17 KFM61192.1 - 1.8e-50 165.0 80.1 8.3e-06 25.5 3.6 22.2 22 0 0 22 22 22 15 Tetratricopeptide repeat TPR_10 PF13374.6 KFM61192.1 - 7.8e-45 149.6 62.5 0.0032 17.3 0.0 21.0 20 1 1 21 21 21 12 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM61192.1 - 8.2e-28 97.7 65.9 2.5e-08 33.7 4.5 7.8 3 2 4 7 7 7 6 MalT-like TPR region Rapsyn_N PF10579.9 KFM61192.1 - 7.2e-18 64.5 20.9 0.0016 18.5 0.0 10.9 7 3 3 10 10 10 5 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.14 KFM61192.1 - 1e-12 47.4 49.0 0.43 11.4 0.0 16.4 16 0 0 16 16 15 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM61192.1 - 9e-10 38.5 40.9 6.9 7.8 0.0 17.5 16 4 3 19 19 19 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM61192.1 - 9.5e-09 35.3 13.2 73 4.3 0.0 14.1 16 0 0 16 16 13 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM61192.1 - 2.5e-07 31.2 43.2 0.18 12.5 0.5 13.3 10 3 3 13 13 13 3 Tetratricopeptide repeat RPN7 PF10602.9 KFM61192.1 - 2.1e-05 24.3 16.6 1.5 8.5 0.1 8.2 3 3 2 6 6 6 2 26S proteasome subunit RPN7 TPR_9 PF13371.6 KFM61192.1 - 2.2e-05 24.5 34.4 0.13 12.4 0.1 11.5 9 4 3 12 12 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM61192.1 - 2.3e-05 24.8 46.7 0.14 12.7 0.6 11.5 8 3 4 13 13 13 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM61192.1 - 0.00013 21.6 31.8 6.2 6.6 0.1 13.8 14 4 1 15 15 14 1 TPR repeat PUB PF09409.10 KFM61192.1 - 0.0039 17.1 0.0 1.7 8.6 0.0 2.6 2 0 0 2 2 2 1 PUB domain TPR_17 PF13431.6 KFM61192.1 - 0.022 15.1 30.2 46 4.7 0.1 13.0 16 0 0 16 16 14 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KFM61192.1 - 0.04 13.8 5.3 0.06 13.3 0.1 3.2 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF1689 PF07954.11 KFM61192.1 - 0.092 13.2 0.1 0.41 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Fis1_TPR_C PF14853.6 KFM61192.1 - 1.3 9.2 14.0 1.2 9.3 1.2 6.4 8 0 0 8 8 6 0 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 KFM61192.1 - 3 8.0 31.2 6.3 6.9 0.2 10.7 7 2 2 10 10 10 0 Anaphase-promoting complex subunit 5 UCH PF00443.29 KFM61193.1 - 2.4e-24 86.2 0.2 2.9e-24 86.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM61193.1 - 1.2e-09 38.3 2.8 1.8e-09 37.7 2.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2894 PF11445.8 KFM61194.1 - 0.011 16.3 0.5 0.023 15.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Mlf1IP PF10248.9 KFM61194.1 - 6.5 6.7 7.3 0.71 9.8 0.5 2.3 1 1 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Glycos_transf_2 PF00535.26 KFM61195.1 - 3.1e-27 95.4 0.0 4.6e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFM61195.1 - 4.1e-10 39.9 0.0 5.9e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFM61195.1 - 1.5e-09 37.8 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KFM61195.1 - 0.0025 18.3 0.0 0.0058 17.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 PPDK_N PF01326.19 KFM61196.1 - 5.6e-71 239.5 0.1 1.1e-70 238.5 0.1 1.4 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 KFM61196.1 - 3e-18 65.3 0.0 8.2e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HTH_Tnp_Tc5 PF03221.16 KFM61198.1 - 8.7e-12 44.9 3.5 2e-11 43.7 0.5 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM61198.1 - 0.00016 21.2 2.7 0.00034 20.2 2.7 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFM61198.1 - 0.002 17.9 0.1 0.0048 16.6 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Phage_antitermQ PF06530.12 KFM61198.1 - 0.0046 16.9 2.4 0.03 14.2 0.6 2.2 2 0 0 2 2 2 1 Phage antitermination protein Q HTH_31 PF13560.6 KFM61198.1 - 0.011 16.0 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 KFM61198.1 - 0.012 15.7 0.3 0.047 13.8 0.1 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 KFM61198.1 - 0.036 14.1 0.1 0.086 12.9 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix GAPES4 PF17157.4 KFM61198.1 - 0.068 13.6 0.0 0.19 12.2 0.0 1.7 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain Mor PF08765.11 KFM61198.1 - 0.069 13.1 0.7 0.39 10.7 0.2 2.1 2 0 0 2 2 2 0 Mor transcription activator family HTH_psq PF05225.16 KFM61198.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain YdaS_antitoxin PF15943.5 KFM61198.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MRP-L20 PF12824.7 KFM61198.1 - 5 7.3 11.5 0.071 13.3 2.5 2.1 2 1 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 DDE_1 PF03184.19 KFM61199.1 - 3.9e-37 127.6 3.0 4.8e-37 127.3 3.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM61199.1 - 0.00025 20.8 0.3 0.00073 19.3 0.1 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM61200.1 - 1e-12 47.9 3.8 5e-09 36.2 0.8 2.7 3 0 0 3 3 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM61200.1 - 2.3e-11 43.5 15.5 1.6e-06 28.2 3.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61200.1 - 6.8e-09 35.8 12.4 4.2e-05 24.0 2.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KFM61200.1 - 4.1e-05 23.8 2.6 5.9e-05 23.3 2.6 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 KFM61200.1 - 0.0003 20.8 0.3 0.00046 20.2 0.3 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHCC PF10276.9 KFM61200.1 - 0.00039 20.4 3.0 0.058 13.4 0.9 2.2 2 0 0 2 2 2 1 Zinc-finger domain zf-C2H2_6 PF13912.6 KFM61200.1 - 0.00058 19.8 10.3 0.093 12.8 0.4 3.0 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM61200.1 - 0.0013 19.1 6.4 0.32 11.5 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM61200.1 - 0.0017 18.6 6.3 0.014 15.7 0.1 2.3 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KFM61200.1 - 0.0019 18.4 1.3 1.9 8.8 0.0 2.2 2 0 0 2 2 2 2 zinc-ribbon CpXC PF14353.6 KFM61200.1 - 0.0034 17.4 1.2 1.3 9.0 0.1 2.0 1 1 1 2 2 2 2 CpXC protein PyrI_C PF02748.15 KFM61200.1 - 0.0078 16.1 2.1 1.1 9.2 0.2 2.1 1 1 1 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.16 KFM61200.1 - 0.0093 16.1 7.1 0.79 9.9 2.2 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger zf-ribbon_3 PF13248.6 KFM61200.1 - 0.012 15.0 4.0 0.29 10.6 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 KFM61200.1 - 0.014 15.3 7.0 0.11 12.4 1.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Prok-RING_1 PF14446.6 KFM61200.1 - 0.016 15.1 0.5 4.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2HE PF16278.5 KFM61200.1 - 0.016 15.6 5.1 0.3 11.5 1.0 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger UBZ_FAAP20 PF15750.5 KFM61200.1 - 0.031 14.2 0.3 2.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Cys_rich_CPXG PF14255.6 KFM61200.1 - 0.033 14.1 2.4 0.39 10.7 2.4 2.2 1 1 0 1 1 1 0 Cysteine-rich CPXCG DUF3268 PF11672.8 KFM61200.1 - 0.033 14.5 0.7 0.033 14.5 0.7 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KFM61200.1 - 0.04 14.0 3.3 0.63 10.2 3.4 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 KFM61200.1 - 0.05 13.2 1.4 4.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM61200.1 - 0.056 13.8 3.4 1.1 9.6 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM61200.1 - 0.064 13.4 0.9 10 6.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_SprT PF17283.2 KFM61200.1 - 0.07 13.1 5.1 0.22 11.4 5.1 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Vps39_2 PF10367.9 KFM61200.1 - 0.1 13.0 1.4 12 6.4 0.1 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 BolA PF01722.18 KFM61200.1 - 0.11 12.8 1.8 0.13 12.5 1.8 1.1 1 0 0 1 1 1 0 BolA-like protein TFIIS_C PF01096.18 KFM61200.1 - 0.16 11.9 2.2 7.9 6.4 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 KFM61200.1 - 0.21 11.6 3.9 0.53 10.3 3.7 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Desulfoferrod_N PF06397.12 KFM61200.1 - 0.21 11.2 3.1 4.6 7.0 0.1 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain C1_2 PF03107.16 KFM61200.1 - 0.22 11.8 0.4 0.22 11.8 0.4 2.4 1 1 1 2 2 2 0 C1 domain Zn-C2H2_12 PF18112.1 KFM61200.1 - 0.23 11.9 5.5 3 8.4 0.8 2.9 2 2 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-HYPF PF07503.12 KFM61200.1 - 0.25 11.2 3.7 7.1 6.5 0.3 2.3 2 0 0 2 2 2 0 HypF finger Zf_RING PF16744.5 KFM61200.1 - 0.41 10.8 2.7 1.6 8.9 0.3 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger zf-C2H2_11 PF16622.5 KFM61200.1 - 0.76 9.6 6.2 5.5 6.8 0.3 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type FYVE PF01363.21 KFM61200.1 - 0.95 9.6 6.0 4.8 7.4 6.0 1.8 1 1 0 1 1 1 0 FYVE zinc finger Zn_ribbon_recom PF13408.6 KFM61200.1 - 1.1 9.8 7.7 5.4 7.6 0.7 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain RFX_DNA_binding PF02257.15 KFM61201.1 - 0.1 13.3 1.2 0.26 11.9 0.3 2.1 2 0 0 2 2 2 0 RFX DNA-binding domain DUF4817 PF16087.5 KFM61202.1 - 2.4e-15 56.1 0.4 4.3e-15 55.2 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 KFM61202.1 - 0.007 17.0 0.1 0.014 16.0 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain zf-C2H2 PF00096.26 KFM61203.1 - 7.2e-17 60.8 20.4 2.9e-06 27.4 1.5 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM61203.1 - 4.8e-14 52.0 16.2 4.6e-08 33.1 0.4 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM61203.1 - 5.7e-12 45.4 17.9 0.00081 20.0 1.2 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM61203.1 - 2.2e-10 40.6 16.3 0.0019 18.6 1.4 3.8 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM61203.1 - 2.8e-09 37.0 8.7 0.00097 19.4 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM61203.1 - 0.00014 22.0 7.2 0.0029 17.9 4.1 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KFM61203.1 - 0.00036 20.3 4.3 0.14 12.0 0.1 2.7 2 1 1 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 KFM61203.1 - 0.00036 20.9 10.4 0.004 17.6 0.5 3.1 1 1 2 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFM61203.1 - 0.00083 19.6 8.8 0.83 10.0 0.5 3.1 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFM61203.1 - 0.0034 17.6 0.4 1.8 8.9 0.0 2.6 1 1 0 2 2 2 1 BolA-like protein Zn-C2H2_12 PF18112.1 KFM61203.1 - 0.0051 17.3 13.0 0.35 11.4 3.3 3.9 3 1 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain zf-RING_5 PF14634.6 KFM61203.1 - 0.011 15.6 5.0 6.3 6.8 0.1 3.2 2 1 1 4 4 4 0 zinc-RING finger domain zf-C2H2_6 PF13912.6 KFM61203.1 - 0.012 15.6 16.6 0.3 11.1 0.9 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger Zf_RING PF16744.5 KFM61203.1 - 0.014 15.5 5.9 3.6 7.8 0.5 3.1 1 1 2 3 3 3 0 KIAA1045 RING finger Zn_Tnp_IS1595 PF12760.7 KFM61203.1 - 0.014 15.3 4.9 0.074 13.0 1.7 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-WRNIP1_ubi PF18279.1 KFM61203.1 - 0.017 15.7 4.8 1.8 9.4 0.0 3.8 4 1 0 4 4 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Prok-RING_1 PF14446.6 KFM61203.1 - 0.025 14.5 3.7 4.8 7.2 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KFM61203.1 - 0.027 14.8 4.4 5.2 7.5 0.1 3.2 3 0 0 3 3 3 0 Ring finger domain zf-Sec23_Sec24 PF04810.15 KFM61203.1 - 0.032 14.3 5.8 5.3 7.2 0.4 3.2 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM61203.1 - 0.048 13.6 0.5 0.048 13.6 0.5 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PHD_4 PF16866.5 KFM61203.1 - 0.051 13.7 0.9 0.55 10.4 0.3 2.1 2 0 0 2 2 2 0 PHD-finger LIM PF00412.22 KFM61203.1 - 0.066 13.4 2.1 0.066 13.4 2.1 2.6 2 1 0 2 2 2 0 LIM domain C1_4 PF07975.12 KFM61203.1 - 0.067 13.4 2.9 0.73 10.1 1.4 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain Elf1 PF05129.13 KFM61203.1 - 0.075 13.1 6.7 0.2 11.7 2.3 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 KFM61203.1 - 0.08 13.1 5.4 5.7 7.2 1.5 2.9 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 KFM61203.1 - 0.081 13.2 7.1 0.65 10.3 1.8 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zinc-ribbons_6 PF07191.12 KFM61203.1 - 0.1 12.6 5.9 0.4 10.7 1.6 2.4 1 1 0 2 2 2 0 zinc-ribbons Baculo_IE-1 PF05290.11 KFM61203.1 - 0.12 12.4 2.9 12 5.8 0.1 2.8 1 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-CHCC PF10276.9 KFM61203.1 - 0.25 11.4 5.5 2 8.5 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger domain DUF2225 PF09986.9 KFM61203.1 - 0.31 10.7 6.5 4.3 7.0 0.2 3.0 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-BED PF02892.15 KFM61203.1 - 0.34 11.0 14.7 6.4 6.9 0.7 3.3 1 1 2 3 3 3 0 BED zinc finger zf_ZIC PF18366.1 KFM61203.1 - 0.46 10.6 9.7 4.4 7.5 0.3 3.2 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-AN1 PF01428.16 KFM61203.1 - 0.51 10.5 10.1 3.9 7.7 0.4 3.0 2 1 1 3 3 3 0 AN1-like Zinc finger zf_UBZ PF18439.1 KFM61203.1 - 0.53 9.9 6.5 2.4 7.8 0.2 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger MRNIP PF15749.5 KFM61203.1 - 0.57 10.9 4.8 0.49 11.1 0.5 2.5 2 1 1 3 3 3 0 MRN-interacting protein GAGA PF09237.11 KFM61203.1 - 0.62 9.9 4.5 6.7 6.6 0.3 2.9 1 1 2 3 3 3 0 GAGA factor FYVE PF01363.21 KFM61203.1 - 0.74 10.0 9.0 17 5.7 9.0 2.4 1 1 1 2 2 2 0 FYVE zinc finger Rubredoxin PF00301.20 KFM61203.1 - 1.3 9.1 6.5 9.7 6.3 0.4 3.1 3 0 0 3 3 3 0 Rubredoxin DUF2256 PF10013.9 KFM61203.1 - 1.6 9.0 8.3 4.6 7.4 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) HNH_5 PF14279.6 KFM61203.1 - 1.7 8.6 8.3 3.1 7.7 0.4 2.6 3 0 0 3 3 2 0 HNH endonuclease Actin_micro PF17003.5 KFM61203.1 - 2 7.5 8.5 15 4.7 3.4 2.8 1 1 1 2 2 2 0 Putative actin-like family NADH-G_4Fe-4S_3 PF10588.9 KFM61203.1 - 2.4 7.8 5.7 1.5 8.4 0.1 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Sgf11 PF08209.11 KFM61203.1 - 2.8 7.6 7.0 7.5 6.2 0.1 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) TPR_8 PF13181.6 KFM61204.1 - 2e-11 43.2 17.0 2.2e-06 27.4 1.5 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM61204.1 - 5.5e-10 38.6 9.4 9.4e-07 28.4 2.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM61204.1 - 5.1e-08 32.4 16.6 0.00012 21.9 1.3 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM61204.1 - 2.6e-07 30.2 0.1 0.00057 19.7 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM61204.1 - 1.1e-06 29.2 0.8 0.018 15.7 0.0 3.1 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM61204.1 - 1e-05 26.0 2.1 0.096 13.6 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM61204.1 - 5.6e-05 23.6 0.7 5.6e-05 23.6 0.7 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM61204.1 - 0.00026 21.1 9.1 0.023 15.1 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM61204.1 - 0.00041 20.6 10.6 0.011 16.0 0.3 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM61204.1 - 0.00056 19.5 7.1 0.054 13.2 0.0 3.7 4 0 0 4 4 4 2 TPR repeat TPR_6 PF13174.6 KFM61204.1 - 0.028 15.0 2.1 0.1 13.3 0.8 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KFM61204.1 - 0.073 12.7 0.3 0.16 11.6 0.3 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Cas_DxTHG PF09455.10 KFM61204.1 - 0.1 12.2 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family TPR_10 PF13374.6 KFM61204.1 - 0.63 10.0 11.2 0.83 9.6 0.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM61204.1 - 3.2 8.0 18.6 1.2 9.5 0.5 4.7 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFM61205.1 - 0.0042 17.6 0.2 0.0064 17.0 0.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFM61205.1 - 0.059 13.7 0.1 0.084 13.2 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM61206.1 - 4.6e-14 51.3 0.1 0.0059 16.6 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM61206.1 - 9.8e-11 41.0 2.5 0.0094 15.7 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM61206.1 - 8.8e-10 37.9 0.0 2.3 8.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM61206.1 - 3.7e-07 30.5 0.1 0.055 14.0 0.0 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFM61206.1 - 7.6e-07 29.4 0.1 9.7 7.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM61206.1 - 9e-07 28.6 2.1 1.7 9.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM61206.1 - 1.2e-06 28.9 0.1 0.15 12.9 0.0 4.7 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM61206.1 - 7e-06 25.6 0.1 0.0056 16.3 0.0 3.5 2 1 2 4 4 4 1 TPR repeat TPR_16 PF13432.6 KFM61206.1 - 2.9e-05 24.6 0.0 0.0012 19.4 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM61206.1 - 3.2e-05 24.0 0.2 0.011 15.8 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM61206.1 - 0.00032 20.9 0.9 0.86 9.9 0.0 3.7 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM61206.1 - 0.00035 20.7 0.1 19 5.9 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KFM61206.1 - 0.0013 18.5 0.1 0.014 15.1 0.0 2.6 3 0 0 3 3 3 1 26S proteasome subunit RPN7 SNAP PF14938.6 KFM61206.1 - 0.0017 17.8 0.6 0.086 12.3 0.1 2.2 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KFM61206.1 - 0.0034 16.8 0.1 1.1 8.6 0.0 2.7 2 1 1 3 3 3 1 MalT-like TPR region HrpB1_HrpK PF09613.10 KFM61206.1 - 0.023 14.3 0.2 7.3 6.2 0.1 3.0 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 KFM61206.1 - 0.025 14.9 0.0 14 6.1 0.0 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KFM61206.1 - 0.074 13.5 0.1 0.47 10.9 0.0 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain NARP1 PF12569.8 KFM61206.1 - 0.27 10.1 9.1 0.43 9.4 0.0 3.1 1 1 1 2 2 1 0 NMDA receptor-regulated protein 1 PDDEXK_1 PF12705.7 KFM61207.1 - 0.00015 21.8 0.0 0.00029 20.8 0.0 1.4 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily PRP3 PF08572.10 KFM61208.1 - 1.3e-80 270.4 12.3 1.3e-80 270.4 12.3 2.4 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KFM61208.1 - 3.6e-13 49.8 0.1 3.6e-13 49.8 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) PWI PF01480.17 KFM61208.1 - 9.9e-07 29.0 0.4 1.5e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 PWI domain DUF1993 PF09351.10 KFM61208.1 - 0.34 11.0 0.0 0.34 11.0 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1993) Spore_III_AB PF09548.10 KFM61208.1 - 0.7 10.0 6.9 3 7.9 0.2 3.4 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) GNAT_acetyltran PF12746.7 KFM61208.1 - 6 6.4 6.4 0.55 9.8 0.6 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase KTI12 PF08433.10 KFM61209.1 - 3e-92 308.9 0.2 3.3e-92 308.8 0.2 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KFM61209.1 - 1.4e-07 31.8 0.0 2.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM61209.1 - 2.1e-05 25.1 0.0 6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KFM61209.1 - 0.00015 21.7 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 KFM61209.1 - 0.0026 17.1 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 KFM61209.1 - 0.042 14.1 0.6 0.65 10.2 0.6 2.6 1 1 0 1 1 1 0 AAA domain Sipho_Gp37 PF14594.6 KFM61209.1 - 0.051 12.6 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein 6PF2K PF01591.18 KFM61209.1 - 0.066 12.5 0.1 0.15 11.3 0.1 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase RNase_PH PF01138.21 KFM61210.1 - 8.6e-25 87.8 0.3 1.1e-24 87.5 0.3 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DHquinase_II PF01220.19 KFM61210.1 - 0.053 13.2 0.5 0.37 10.4 0.5 2.0 1 1 0 1 1 1 0 Dehydroquinase class II Hat1_N PF10394.9 KFM61211.1 - 0.023 15.0 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus Exo_endo_phos PF03372.23 KFM61212.1 - 1.2e-05 25.0 0.1 2e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PIRT PF15099.6 KFM61213.1 - 0.002 17.7 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family MFS_4 PF06779.14 KFM61213.1 - 0.043 13.1 0.1 0.05 12.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB DUF3784 PF12650.7 KFM61213.1 - 0.076 13.2 0.9 0.57 10.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Neurensin PF14927.6 KFM61213.1 - 0.42 10.3 3.3 2.6 7.7 3.3 1.9 1 1 0 1 1 1 0 Neurensin YrzO PF14142.6 KFM61214.1 - 0.042 13.7 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 YrzO-like protein Fer2_BFD PF04324.15 KFM61214.1 - 0.1 13.0 0.2 2.7 8.4 0.0 2.3 1 1 1 2 2 2 0 BFD-like [2Fe-2S] binding domain zf-C2H2 PF00096.26 KFM61216.1 - 3.1e-05 24.2 2.1 3.1e-05 24.2 2.1 1.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61216.1 - 9.2e-05 23.0 1.1 9.2e-05 23.0 1.1 2.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM61216.1 - 0.0008 19.1 1.4 0.0012 18.5 1.4 1.3 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-Di19 PF05605.12 KFM61216.1 - 0.028 14.7 0.6 0.034 14.4 0.5 1.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KFM61216.1 - 0.031 13.9 0.2 0.046 13.3 0.2 1.3 1 0 0 1 1 1 0 MYST family zinc finger domain zf-met PF12874.7 KFM61216.1 - 0.032 14.6 0.2 0.032 14.6 0.2 2.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 KFM61216.1 - 0.041 13.8 2.0 0.057 13.3 2.0 1.2 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-H2C2_2 PF13465.6 KFM61216.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.4 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KFM61217.1 - 6.1e-11 42.2 9.6 2.3e-06 27.7 1.8 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61217.1 - 5.1e-10 39.3 8.0 5.3e-05 23.7 0.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM61217.1 - 1.8e-05 24.4 5.6 6.1e-05 22.7 2.0 2.2 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM61217.1 - 2.6e-05 24.1 7.7 0.0055 16.7 0.2 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM61217.1 - 3.1e-05 24.2 2.5 0.006 16.9 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFM61217.1 - 8.9e-05 22.8 9.6 0.16 12.4 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KFM61217.1 - 0.00022 21.5 2.6 0.00024 21.3 2.6 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KFM61217.1 - 0.0005 20.1 4.1 0.064 13.4 0.2 2.3 1 1 1 2 2 2 2 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFM61217.1 - 0.00095 19.0 1.9 0.12 12.4 0.2 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM61217.1 - 0.0011 18.5 4.4 0.11 12.1 1.0 2.5 2 1 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFM61217.1 - 0.0034 18.0 1.3 0.0049 17.6 1.3 1.3 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-AN1 PF01428.16 KFM61217.1 - 0.0043 17.2 5.4 0.16 12.2 1.8 2.1 1 1 1 2 2 2 1 AN1-like Zinc finger zf-LYAR PF08790.11 KFM61217.1 - 0.0061 16.4 5.0 0.38 10.7 0.1 2.2 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 KFM61217.1 - 0.0073 16.6 1.6 1.6 9.1 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.14 KFM61217.1 - 0.0097 15.8 3.1 0.44 10.5 0.9 2.2 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif DUF2256 PF10013.9 KFM61217.1 - 0.011 15.8 3.7 0.84 9.8 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc-ribbons_6 PF07191.12 KFM61217.1 - 0.02 14.8 2.3 0.029 14.4 2.3 1.3 1 0 0 1 1 1 0 zinc-ribbons Zn_ribbon_SprT PF17283.2 KFM61217.1 - 0.033 14.1 3.5 0.042 13.8 0.5 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-CSL PF05207.13 KFM61217.1 - 0.038 13.7 2.8 0.052 13.3 2.8 1.2 1 0 0 1 1 1 0 CSL zinc finger zf_ZIC PF18366.1 KFM61217.1 - 0.05 13.7 2.5 1.9 8.7 0.0 2.1 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-HIT PF04438.16 KFM61217.1 - 0.061 13.2 3.0 2.3 8.1 0.4 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-MYST PF17772.1 KFM61217.1 - 0.084 12.5 3.0 0.72 9.5 0.4 2.0 1 1 1 2 2 2 0 MYST family zinc finger domain Desulfoferrod_N PF06397.12 KFM61217.1 - 0.12 12.1 1.9 0.6 9.8 0.3 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-BED PF02892.15 KFM61217.1 - 0.12 12.4 9.6 1.4 9.0 3.9 2.1 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 KFM61217.1 - 0.2 11.5 11.2 0.081 12.7 6.3 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Zf_RING PF16744.5 KFM61217.1 - 0.22 11.7 4.4 4.1 7.6 0.3 2.2 1 1 1 2 2 2 0 KIAA1045 RING finger FYVE PF01363.21 KFM61217.1 - 0.37 11.0 7.6 4.6 7.5 0.6 2.1 1 1 1 2 2 2 0 FYVE zinc finger zf-CW PF07496.15 KFM61217.1 - 0.39 10.8 4.8 0.96 9.5 4.8 1.7 1 1 0 1 1 1 0 CW-type Zinc Finger DUF629 PF04780.12 KFM61217.1 - 0.45 9.0 5.5 0.26 9.8 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Ribosomal_L37ae PF01780.19 KFM61217.1 - 1.8 8.7 6.0 5.3 7.2 1.8 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-C2H2_6 PF13912.6 KFM61218.1 - 0.0081 16.1 3.6 0.013 15.4 3.6 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger FLYWCH PF04500.16 KFM61221.1 - 7e-14 51.7 3.4 9.7e-14 51.2 3.4 1.2 1 0 0 1 1 1 1 FLYWCH zinc finger domain Sulfate_transp PF00916.20 KFM61223.1 - 2.5e-105 352.4 22.7 4.2e-105 351.6 22.7 1.4 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFM61223.1 - 3.6e-26 91.1 0.2 6.6e-26 90.2 0.2 1.5 1 0 0 1 1 1 1 STAS domain Phage_holin_2_3 PF16080.5 KFM61223.1 - 0.031 14.0 0.1 19 5.1 0.0 3.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 MFS_MOT1 PF16983.5 KFM61223.1 - 2.5 8.6 8.9 0.45 10.9 3.3 2.7 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily PrmA PF06325.13 KFM61224.1 - 8.4e-10 38.5 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFM61224.1 - 1.4e-09 38.5 0.1 7.7e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM61224.1 - 6.1e-08 33.2 0.1 3.6e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM61224.1 - 1.2e-07 31.7 0.0 2.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM61224.1 - 1e-06 28.4 0.1 2.4e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PRMT5 PF05185.16 KFM61224.1 - 1.9e-06 27.8 0.1 4.7e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 KFM61224.1 - 1.4e-05 24.9 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFM61224.1 - 0.00054 19.4 0.0 0.0011 18.4 0.0 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 KFM61224.1 - 0.00098 19.8 0.0 0.0054 17.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFM61224.1 - 0.0014 18.6 0.1 0.0027 17.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM61224.1 - 0.0017 18.0 0.0 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KFM61224.1 - 0.0022 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5_C PF17286.2 KFM61224.1 - 0.0025 17.7 0.4 0.0048 16.8 0.4 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_2 PF00891.18 KFM61224.1 - 0.0033 16.8 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 KFM61224.1 - 0.0039 16.3 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KFM61224.1 - 0.0093 16.0 0.8 0.02 14.9 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFM61224.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KFM61224.1 - 0.015 15.0 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KFM61224.1 - 0.018 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 KFM61224.1 - 0.05 14.6 0.0 0.14 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KFM61224.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Histone_H2A_C PF16211.5 KFM61225.1 - 6.7e-21 73.7 0.6 1.3e-20 72.8 0.6 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM61225.1 - 2.6e-11 44.0 0.0 3.2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM61225.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L7Ae PF01248.26 KFM61226.1 - 1.6e-05 24.5 2.0 2.3e-05 24.0 0.3 2.2 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MFS_1_like PF12832.7 KFM61228.1 - 6e-76 255.8 19.6 7.4e-76 255.5 19.6 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM61228.1 - 1.6e-12 47.0 44.9 2.7e-07 29.8 23.2 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFM61228.1 - 1.5e-06 27.5 12.5 1.5e-06 27.5 12.5 2.0 2 0 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 KFM61228.1 - 0.0053 15.6 23.7 0.12 11.1 11.5 2.5 2 1 0 2 2 2 2 LacY proton/sugar symporter Carn_acyltransf PF00755.20 KFM61229.1 - 7e-197 655.7 0.0 7.9e-197 655.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ion_trans PF00520.31 KFM61230.1 - 6.6e-08 32.1 25.5 1.4e-07 31.0 25.5 1.5 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM61230.1 - 9.5e-07 27.8 12.7 9.5e-07 27.8 12.7 2.7 3 0 0 3 3 3 1 Polycystin cation channel LRR19-TM PF15176.6 KFM61230.1 - 0.071 13.1 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4371 PF14291.6 KFM61231.1 - 1.3e-10 41.3 0.0 2.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) BTB_2 PF02214.22 KFM61232.1 - 1.6e-28 98.9 0.1 2.1e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain Shal-type PF11601.8 KFM61232.1 - 3.6e-15 55.2 13.8 4.7e-15 54.8 13.8 1.2 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal BTB_3 PF16017.5 KFM61232.1 - 7.6e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro38C2 PF17677.1 KFM61233.1 - 4.1e-11 42.8 0.0 6.7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain TSP_1 PF00090.19 KFM61234.1 - 4.4e-15 55.6 26.3 1e-08 35.2 8.7 3.6 2 1 2 4 4 4 2 Thrombospondin type 1 domain 7tm_2 PF00002.24 KFM61234.1 - 1.8e-07 30.7 10.3 2.6e-07 30.2 10.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Bunya_G2 PF03563.13 KFM61234.1 - 0.015 14.5 1.9 0.029 13.6 1.9 1.4 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 EGF_MSP1_1 PF12946.7 KFM61234.1 - 0.019 15.0 1.5 0.019 15.0 1.5 2.5 2 0 0 2 2 2 0 MSP1 EGF domain 1 7tm_3 PF00003.22 KFM61234.1 - 0.057 13.1 9.6 0.1 12.3 9.6 1.4 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Insulin_TMD PF17870.1 KFM61235.1 - 3.8 7.6 7.3 1.7 8.8 0.2 2.8 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment DUF1681 PF07933.14 KFM61236.1 - 2.1e-25 89.1 0.3 3.3e-25 88.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Bin3 PF06859.12 KFM61237.1 - 9.4e-30 103.4 0.1 3.8e-29 101.5 0.0 2.1 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 KFM61237.1 - 5.2e-11 42.6 0.0 7.8e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM61237.1 - 6.5e-11 42.3 0.0 1.8e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM61237.1 - 2.2e-10 41.1 0.0 1.1e-07 32.4 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM61237.1 - 8.1e-08 32.9 0.2 3.2e-07 31.0 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM61237.1 - 1.2e-07 32.3 0.0 2.1e-05 25.1 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFM61237.1 - 1.3e-06 28.4 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFM61237.1 - 4.5e-05 23.0 1.5 9e-05 22.0 0.0 2.3 3 0 0 3 3 3 1 Putative methyltransferase PCMT PF01135.19 KFM61237.1 - 6.6e-05 22.7 0.0 0.00018 21.4 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KFM61237.1 - 0.00021 20.9 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KFM61237.1 - 0.00031 20.2 0.0 0.0012 18.2 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KFM61237.1 - 0.0016 18.6 0.0 0.0045 17.1 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase PrmA PF06325.13 KFM61237.1 - 0.0021 17.5 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KFM61237.1 - 0.0058 16.0 0.0 0.032 13.5 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.17 KFM61237.1 - 0.03 13.5 0.0 0.43 9.7 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_32 PF13679.6 KFM61237.1 - 0.043 13.8 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.16 KFM61237.1 - 0.097 11.9 0.1 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain MCM2_N PF12619.8 KFM61237.1 - 0.45 10.8 8.0 0.14 12.5 0.5 3.0 3 0 0 3 3 3 0 Mini-chromosome maintenance protein 2 HELP PF03451.14 KFM61238.1 - 5.3e-14 51.8 0.0 9.7e-14 51.0 0.0 1.5 1 1 0 1 1 1 1 HELP motif WD40 PF00400.32 KFM61238.1 - 0.068 14.1 0.2 0.16 12.9 0.2 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat WD40 PF00400.32 KFM61239.1 - 8.1e-13 48.6 7.9 0.0093 16.8 0.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM61239.1 - 4.7e-09 36.4 0.0 0.002 18.4 0.0 3.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM61239.1 - 4.1e-05 22.7 0.0 9.2e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KFM61239.1 - 0.0056 15.1 0.0 0.15 10.3 0.0 2.1 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KFM61239.1 - 0.016 15.7 2.2 1.8 9.1 0.3 4.3 5 2 1 6 6 6 0 PQQ-like domain CPSF_A PF03178.15 KFM61239.1 - 0.029 13.7 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 CPSF A subunit region VCBS PF13517.6 KFM61239.1 - 0.33 11.6 2.4 4.9 7.8 0.0 3.7 4 1 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella WD40 PF00400.32 KFM61240.1 - 0.00017 22.3 0.4 0.63 11.0 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Fanconi_A_N PF15865.5 KFM61243.1 - 1.4e-11 44.4 0.1 1.6e-11 44.2 0.1 1.0 1 0 0 1 1 1 1 Fanconi anaemia group A protein N terminus Spindle_Spc25 PF08234.12 KFM61244.1 - 0.064 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 I-set PF07679.16 KFM61246.1 - 2.3e-29 101.3 0.1 1.5e-14 53.8 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM61246.1 - 3.5e-27 94.8 0.1 7.6e-12 45.7 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFM61246.1 - 6.4e-17 61.7 0.1 2.7e-09 37.2 0.0 3.1 3 0 0 3 3 2 2 Immunoglobulin domain ig PF00047.25 KFM61246.1 - 4.5e-16 58.8 0.0 5.6e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM61246.1 - 5.7e-08 32.9 1.5 0.061 13.5 0.1 5.0 2 2 1 3 3 3 2 Immunoglobulin V-set domain EF-hand_1 PF00036.32 KFM61246.1 - 1.7e-07 30.3 0.4 0.015 14.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM61246.1 - 6e-07 28.9 0.1 0.042 13.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFM61246.1 - 0.0001 21.6 0.0 0.33 10.5 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFM61246.1 - 0.00036 20.9 0.4 0.00083 19.8 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair Ig_C17orf99 PF17736.1 KFM61246.1 - 0.00069 19.6 0.0 0.038 14.0 0.0 2.8 2 0 0 2 2 2 1 C17orf99 Ig domain C2-set_2 PF08205.12 KFM61246.1 - 0.001 19.1 0.0 0.83 9.8 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM61246.1 - 0.0042 16.6 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM61246.1 - 0.0073 16.4 0.2 1.4 9.0 0.1 2.8 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFM61246.1 - 0.01 16.2 0.0 0.75 10.2 0.0 3.1 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set_CD47 PF08204.11 KFM61246.1 - 0.13 12.2 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain V-ATPase_H_C PF11698.8 KFM61247.1 - 0.013 15.6 0.2 0.014 15.5 0.2 1.0 1 0 0 1 1 1 0 V-ATPase subunit H TraI_2_C PF07515.11 KFM61247.1 - 0.04 13.9 0.2 0.044 13.7 0.2 1.1 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term MBF2 PF15868.5 KFM61247.1 - 0.042 14.4 0.0 0.049 14.2 0.0 1.1 1 0 0 1 1 1 0 Transcription activator MBF2 C2 PF00168.30 KFM61248.1 - 5.2e-24 84.5 0.2 4e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain gag_pre-integrs PF13976.6 KFM61249.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain EF-hand_7 PF13499.6 KFM61250.1 - 6.7e-11 42.5 0.1 1.7e-10 41.2 0.1 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM61250.1 - 4.6e-10 38.3 0.0 3.4e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM61250.1 - 8.9e-08 31.5 0.0 9.5e-06 25.2 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KFM61250.1 - 9.2e-06 24.9 0.1 0.0071 15.8 0.0 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 KFM61250.1 - 3.3e-05 24.2 0.0 7.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KFM61250.1 - 0.00079 19.2 0.1 1 9.2 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 KFM61250.1 - 0.0011 19.1 0.9 0.0045 17.2 0.2 2.4 2 1 0 2 2 2 1 Dockerin type I domain SMC_N PF02463.19 KFM61251.1 - 1e-30 106.8 49.5 3.1e-30 105.2 49.5 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFM61251.1 - 1.9e-22 79.7 0.2 1.1e-21 77.4 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFM61251.1 - 7.1e-06 26.0 0.8 7.1e-06 26.0 0.8 3.8 4 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF812 PF05667.11 KFM61251.1 - 0.005 15.8 1.9 0.005 15.8 1.9 5.2 3 2 2 5 5 5 2 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 KFM61251.1 - 0.011 15.8 20.4 0.31 11.1 0.1 6.0 4 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus SbcCD_C PF13558.6 KFM61251.1 - 0.034 14.4 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CSN7a_helixI PF18392.1 KFM61251.1 - 6.9 6.7 8.0 42 4.1 2.4 4.3 3 0 0 3 3 3 0 COP9 signalosome complex subunit 7a helix I domain Bac_surface_Ag PF01103.23 KFM61252.1 - 6.2e-51 173.8 0.0 7.3e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 KFM61252.1 - 0.018 15.6 0.2 0.031 14.9 0.2 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat UDG PF03167.19 KFM61253.1 - 0.065 13.2 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily TPR_12 PF13424.6 KFM61261.1 - 0.038 14.3 0.1 0.07 13.4 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat VPS13_mid_rpt PF16910.5 KFM61261.1 - 0.047 13.1 0.1 0.074 12.5 0.1 1.5 1 1 0 1 1 1 0 Repeating coiled region of VPS13 TPR_2 PF07719.17 KFM61261.1 - 0.17 12.1 0.2 0.32 11.2 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.9 KFM61262.1 - 0.044 13.5 0.1 0.047 13.4 0.1 1.0 1 0 0 1 1 1 0 26S proteasome subunit RPN7 PPS_PS PF02006.16 KFM61265.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase Methyltransf_34 PF11312.8 KFM61266.1 - 0.00054 19.3 0.0 0.005 16.1 0.0 2.0 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase Methyltransf_23 PF13489.6 KFM61266.1 - 0.0096 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CN_hydrolase PF00795.22 KFM61267.1 - 2.5e-65 220.4 0.0 3.1e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HIT PF01230.23 KFM61267.1 - 1.2e-23 83.7 0.0 3.2e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFM61267.1 - 4.2e-06 27.2 0.0 1.9e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding SnoaL PF07366.12 KFM61267.1 - 0.19 11.5 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SHQ1 PF04925.15 KFM61268.1 - 5.4e-67 224.7 1.6 7.9e-67 224.2 1.6 1.2 1 0 0 1 1 1 1 SHQ1 protein RPE65 PF03055.15 KFM61269.1 - 1e-58 199.7 0.1 1.2e-58 199.5 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 KFM61270.1 - 1e-13 51.3 0.0 1.1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 KFM61271.1 - 4.4e-79 266.8 0.0 5.3e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF5074 PF16819.5 KFM61271.1 - 0.028 14.5 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) EF-hand_1 PF00036.32 KFM61272.1 - 1.6e-20 71.0 10.4 0.00015 21.1 0.0 6.1 6 1 0 6 6 6 4 EF hand EF-hand_7 PF13499.6 KFM61272.1 - 5.7e-17 61.9 6.3 1.5e-07 31.7 0.2 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFM61272.1 - 1.1e-15 56.2 8.3 0.00035 20.3 0.0 5.9 6 1 1 7 7 6 4 EF-hand domain EF-hand_5 PF13202.6 KFM61272.1 - 4.6e-13 48.0 11.7 0.00055 19.3 0.4 4.9 5 0 0 5 5 5 4 EF hand SPARC_Ca_bdg PF10591.9 KFM61272.1 - 6.8e-05 23.2 10.9 0.0047 17.2 2.0 3.4 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KFM61272.1 - 0.0002 21.1 10.6 6.7 6.6 0.2 5.6 5 1 1 6 6 6 1 EF-hand domain pair ArsD PF06953.11 KFM61272.1 - 0.015 15.7 0.4 0.061 13.7 0.2 2.0 1 1 1 2 2 2 0 Arsenical resistance operon trans-acting repressor ArsD OAD_gamma PF04277.13 KFM61272.1 - 0.047 14.3 0.1 0.1 13.2 0.1 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4004 PF13171.6 KFM61272.1 - 0.052 13.8 0.9 13 5.9 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4004) RhoGAP PF00620.27 KFM61272.1 - 0.085 12.7 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 RhoGAP domain DUF1180 PF06679.12 KFM61272.1 - 0.12 12.8 0.2 0.18 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) S_100 PF01023.19 KFM61272.1 - 0.29 10.9 3.0 16 5.3 0.0 3.7 4 0 0 4 4 4 0 S-100/ICaBP type calcium binding domain DUF1840 PF08895.11 KFM61272.1 - 0.31 11.4 0.0 0.31 11.4 0.0 2.3 2 2 1 3 3 3 0 Domain of unknown function (DUF1840) FumaraseC_C PF10415.9 KFM61272.1 - 0.42 11.1 1.5 4.3 7.8 0.1 3.1 3 1 0 3 3 3 0 Fumarase C C-terminus Dockerin_1 PF00404.18 KFM61272.1 - 0.43 10.8 3.3 1.8 8.8 0.0 3.3 4 1 0 4 4 3 0 Dockerin type I domain Excalibur PF05901.11 KFM61272.1 - 0.51 11.0 2.5 14 6.4 0.0 3.4 3 0 0 3 3 3 0 Excalibur calcium-binding domain EF-hand_4 PF12763.7 KFM61272.1 - 5.7 7.0 7.5 3.5 7.6 0.0 3.5 4 1 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand Innexin PF00876.18 KFM61273.1 - 1.3e-82 278.0 5.8 1.5e-82 277.8 5.8 1.0 1 0 0 1 1 1 1 Innexin DHODB_Fe-S_bind PF10418.9 KFM61273.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Apolipoprotein PF01442.18 KFM61278.1 - 0.0027 17.6 17.1 0.016 15.1 2.1 3.7 2 2 1 3 3 3 2 Apolipoprotein A1/A4/E domain DUF4279 PF14106.6 KFM61278.1 - 1.3 9.2 8.9 1.6 9.0 0.3 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4279) ABC_tran_CTD PF16326.5 KFM61278.1 - 2.3 8.5 20.7 0.53 10.6 0.9 5.5 4 2 0 4 4 4 0 ABC transporter C-terminal domain WXG100 PF06013.12 KFM61278.1 - 3.3 8.0 7.2 22 5.4 0.1 5.1 4 2 2 6 6 6 0 Proteins of 100 residues with WXG LSM PF01423.22 KFM61279.1 - 4e-21 74.5 0.2 4.6e-21 74.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFM61279.1 - 0.00059 19.9 0.0 0.00068 19.7 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain STT3_PglB_C PF18527.1 KFM61279.1 - 0.13 12.3 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 STT3/PglB C-terminal beta-barrel domain MFS_1 PF07690.16 KFM61280.1 - 3.7e-08 32.7 4.4 4.1e-08 32.6 4.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM61280.1 - 0.0034 16.3 2.3 0.0034 16.3 2.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TMEM52 PF14979.6 KFM61281.1 - 0.0041 17.0 0.5 0.089 12.7 0.1 2.5 2 1 1 3 3 3 1 Transmembrane 52 PIRT PF15099.6 KFM61281.1 - 0.0043 16.6 0.4 0.0059 16.2 0.4 1.2 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Claudin_2 PF13903.6 KFM61281.1 - 0.0091 15.8 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2721 PF11026.8 KFM61281.1 - 0.037 13.9 0.2 0.056 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) TMEM174 PF15029.6 KFM61281.1 - 5.6 6.6 5.6 3.2 7.4 1.1 2.2 2 1 1 3 3 3 0 Transmembrane protein 174 BK_channel_a PF03493.18 KFM61282.1 - 0.015 15.4 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit PI-PLC-X PF00388.19 KFM61283.1 - 1.4e-64 216.0 0.1 3e-64 215.0 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.11 KFM61283.1 - 0.00029 21.3 2.4 0.0012 19.3 1.9 2.2 1 1 1 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.17 KFM61283.1 - 0.00036 20.3 0.0 0.0037 17.0 0.0 2.0 1 1 1 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Phage_int_SAM_1 PF02899.17 KFM61283.1 - 0.012 15.9 0.3 0.55 10.6 0.1 2.7 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain PH PF00169.29 KFM61283.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 PH domain SH2 PF00017.24 KFM61284.1 - 9.6e-22 76.9 0.1 1.5e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFM61284.1 - 7.9e-13 47.8 0.3 7.9e-13 47.8 0.3 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFM61284.1 - 1.2e-11 44.3 0.1 1.9e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM61284.1 - 3.8e-07 29.7 0.2 6.5e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH2_2 PF14633.6 KFM61284.1 - 1.4e-05 24.6 0.0 3.5e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 SH2 domain RBFA PF02033.18 KFM61287.1 - 2e-10 41.1 0.0 3.6e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Ribosome-binding factor A EnY2 PF10163.9 KFM61288.1 - 6.5e-27 93.7 2.1 3.6e-12 46.5 0.2 3.0 1 1 2 3 3 3 3 Transcription factor e(y)2 TetR_N PF00440.23 KFM61288.1 - 0.0044 16.8 0.1 0.66 9.8 0.0 2.7 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family Band_7 PF01145.25 KFM61288.1 - 0.02 14.9 0.1 0.042 13.8 0.1 1.6 1 1 0 1 1 1 0 SPFH domain / Band 7 family SRP19 PF01922.17 KFM61288.1 - 0.095 13.7 0.1 24 6.0 0.0 2.5 1 1 1 2 2 2 0 SRP19 protein zf-C2H2_4 PF13894.6 KFM61289.1 - 1.9e-34 115.4 164.7 0.0013 19.4 1.7 18.9 18 0 0 18 18 18 16 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM61289.1 - 3.1e-23 80.9 174.8 9.8e-05 22.6 4.6 18.9 18 1 0 18 18 18 15 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM61289.1 - 8.4e-21 73.4 149.0 4.4e-08 33.2 0.8 20.9 21 1 0 21 21 21 9 Zinc-finger double domain zf-C2H2_2 PF12756.7 KFM61289.1 - 1.1e-05 25.7 105.4 0.008 16.5 4.4 14.0 7 4 6 14 14 14 7 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM61289.1 - 5.3e-05 22.9 10.3 0.00013 21.7 1.9 15.9 18 0 0 18 18 18 9 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM61289.1 - 0.0017 18.6 0.8 0.026 14.8 0.1 16.3 17 0 0 17 17 17 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM61289.1 - 0.0023 18.2 1.6 0.0023 18.2 1.6 12.7 10 2 3 13 13 13 5 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFM61289.1 - 0.013 15.9 1.1 0.013 15.9 1.1 14.2 16 0 0 16 16 16 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFM61289.1 - 0.044 14.2 0.2 0.044 14.2 0.2 12.3 12 4 2 14 14 13 0 C2HE / C2H2 / C2HC zinc-binding finger BolA PF01722.18 KFM61289.1 - 0.17 12.2 18.0 1.3 9.3 0.0 6.0 7 1 0 7 7 6 0 BolA-like protein UPF0728 PF15092.6 KFM61289.1 - 2.8 7.8 5.1 11 6.0 0.0 4.0 3 1 1 4 4 4 0 Uncharacterised protein family UPF0728 RRM_1 PF00076.22 KFM61290.1 - 5.9e-31 106.1 2.5 4.2e-08 32.9 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KIND PF16474.5 KFM61291.1 - 3.9e-15 56.3 0.1 4.2e-15 56.2 0.1 1.0 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain Microtub_bind PF13931.6 KFM61292.1 - 0.067 13.6 2.6 0.098 13.0 0.4 1.9 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding zf-B_box PF00643.24 KFM61292.1 - 0.25 11.5 6.8 0.87 9.8 0.9 2.3 2 0 0 2 2 2 0 B-box zinc finger zf-piccolo PF05715.13 KFM61292.1 - 0.82 9.9 5.3 2.4 8.4 0.6 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger WD40 PF00400.32 KFM61293.1 - 3.9e-18 65.5 15.8 7.3e-07 29.8 1.4 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM61293.1 - 3.3e-07 30.5 0.2 0.0002 21.6 0.1 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM61293.1 - 1.5e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFM61293.1 - 0.044 12.4 0.6 0.74 8.4 0.3 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CAF1C_H4-bd PF12265.8 KFM61294.1 - 0.0021 18.3 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex SRP54_N PF02881.19 KFM61294.1 - 0.11 12.7 0.3 0.17 12.1 0.3 1.3 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain UPF0203 PF05254.12 KFM61295.1 - 0.027 14.7 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) CutA1 PF03091.15 KFM61296.1 - 8.4e-39 131.4 0.0 1.4e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DUF4560 PF15118.6 KFM61296.1 - 0.014 15.3 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4560) DGOK PF05035.12 KFM61296.1 - 0.074 11.9 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase Myb_DNA-bind_5 PF13873.6 KFM61297.1 - 1e-06 28.7 0.1 1.1e-06 28.6 0.1 1.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain LIM PF00412.22 KFM61298.1 - 4e-40 135.8 53.4 4.7e-14 52.4 6.4 4.2 4 0 0 4 4 4 4 LIM domain DUF4749 PF15936.5 KFM61298.1 - 0.00027 22.0 0.0 0.00027 22.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFM61299.1 - 1.6e-13 50.8 0.0 2.8e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM61299.1 - 1e-08 34.9 0.1 1.8e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM61299.1 - 0.0024 18.1 0.0 0.0053 17.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 KFM61299.1 - 0.069 14.3 57.9 26 6.0 48.8 4.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4749) Sec20 PF03908.13 KFM61300.1 - 0.021 14.7 1.3 0.056 13.4 1.3 1.8 1 0 0 1 1 1 0 Sec20 RRM_1 PF00076.22 KFM61302.1 - 1e-09 38.1 0.0 2.4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM61302.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF2624 PF11116.8 KFM61302.1 - 0.043 14.7 1.4 0.37 11.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) MerR-DNA-bind PF09278.11 KFM61302.1 - 0.083 13.4 0.0 0.33 11.5 0.0 2.1 1 0 0 1 1 1 0 MerR, DNA binding Argos PF11581.8 KFM61302.1 - 0.091 12.8 1.5 0.21 11.6 1.5 1.6 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos HTH_40 PF14493.6 KFM61302.1 - 3.5 8.1 7.3 2.2 8.8 1.2 3.2 3 1 2 5 5 5 0 Helix-turn-helix domain FOP_dimer PF09398.10 KFM61303.1 - 1.2e-10 41.4 0.1 1.5e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KFM61303.1 - 1.2e-05 24.3 0.1 1.6e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 LisH Fn_bind PF02986.14 KFM61305.1 - 0.033 13.9 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin binding repeat ATG16 PF08614.11 KFM61306.1 - 0.001 19.4 25.8 0.001 19.4 25.8 5.3 1 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KFM61306.1 - 0.0087 15.7 12.8 0.0087 15.7 12.8 5.7 2 2 2 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 KFM61306.1 - 0.023 15.1 2.5 0.023 15.1 2.5 9.9 3 3 4 7 7 7 0 Cell division protein ZapB TBCA PF02970.16 KFM61307.1 - 0.031 14.6 0.4 0.031 14.6 0.4 3.1 2 1 1 3 3 3 0 Tubulin binding cofactor A Rb_C PF08934.10 KFM61307.1 - 0.075 12.8 0.6 0.14 12.0 0.6 1.4 1 0 0 1 1 1 0 Rb C-terminal domain TPR_MLP1_2 PF07926.12 KFM61307.1 - 0.46 10.6 23.8 9.3 6.3 0.3 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4047 PF13256.6 KFM61307.1 - 1.9 8.7 16.9 0.077 13.2 6.2 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4047) THOC7 PF05615.13 KFM61307.1 - 2.3 8.5 18.3 0.46 10.8 12.3 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 DUF1410 PF07198.11 KFM61307.1 - 2.6 8.6 10.7 0.65 10.5 2.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1410) NPV_P10 PF05531.12 KFM61307.1 - 3.1 8.3 7.6 5.6 7.5 0.1 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RNA_pol_Rpb1_5 PF04998.17 KFM61307.1 - 3.1 7.1 6.4 3.7 6.9 6.4 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF3450 PF11932.8 KFM61307.1 - 5.3 6.3 14.0 0.78 9.0 8.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Cep57_CLD_2 PF14197.6 KFM61307.1 - 6.1 7.0 18.6 6.3 7.0 0.4 3.8 2 1 0 3 3 3 0 Centrosome localisation domain of PPC89 SHE3 PF17078.5 KFM61308.1 - 0.0012 18.7 10.1 0.0012 18.7 10.1 8.1 1 1 5 7 7 7 3 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 KFM61308.1 - 0.0074 16.3 15.6 0.0074 16.3 15.6 11.0 2 2 6 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Orbi_VP6 PF01516.16 KFM61308.1 - 0.052 13.1 3.1 0.069 12.7 0.3 2.2 2 0 0 2 2 2 0 Orbivirus helicase VP6 DUF150 PF02576.17 KFM61308.1 - 0.84 10.1 3.3 9.7 6.7 0.0 3.7 3 0 0 3 3 3 0 RimP N-terminal domain Fez1 PF06818.15 KFM61308.1 - 0.93 9.9 137.1 0.67 10.4 18.9 7.8 1 1 6 8 8 8 0 Fez1 SVIP PF15811.5 KFM61309.1 - 5.3e-18 65.3 6.6 5.8e-18 65.1 6.6 1.0 1 0 0 1 1 1 1 Small VCP/p97-interacting protein TMA7 PF09072.10 KFM61309.1 - 0.065 14.1 1.7 0.065 14.1 1.7 1.5 1 1 1 2 2 2 0 Translation machinery associated TMA7 RhoGAP PF00620.27 KFM61309.1 - 0.11 12.4 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 RhoGAP domain Radial_spoke_3 PF06098.11 KFM61309.1 - 0.25 10.6 6.9 0.28 10.4 6.9 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 Ank_5 PF13857.6 KFM61311.1 - 0.14 12.5 0.0 0.41 11.0 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KFM61312.1 - 5.1e-10 39.3 0.2 0.00063 20.1 0.1 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFM61312.1 - 3.5e-08 33.1 0.5 0.004 17.5 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFM61312.1 - 7.1e-08 32.9 0.1 0.00011 22.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM61312.1 - 8.4e-07 29.5 0.0 1.3e-06 28.9 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM61312.1 - 0.0056 17.0 0.5 0.036 14.4 0.2 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) DUF2996 PF11210.8 KFM61313.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) PRD PF00874.20 KFM61314.1 - 0.022 15.0 0.1 0.025 14.9 0.1 1.1 1 0 0 1 1 1 0 PRD domain FAD_binding_3 PF01494.19 KFM61317.1 - 7.6e-17 61.6 0.0 3.4e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 KFM61317.1 - 0.00056 19.1 0.0 0.0071 15.4 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.14 KFM61317.1 - 0.05 12.5 0.0 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase UPF0564 PF10595.9 KFM61318.1 - 0.00019 20.7 6.8 0.00019 20.7 6.8 1.6 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 DUF3747 PF12565.8 KFM61318.1 - 0.013 14.9 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) ETC_C1_NDUFA5 PF04716.14 KFM61318.1 - 0.016 15.0 0.9 0.031 14.1 0.9 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region OmpH PF03938.14 KFM61318.1 - 0.36 11.1 12.4 0.55 10.6 12.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BAG PF02179.16 KFM61318.1 - 0.82 10.2 8.6 3.5 8.1 2.2 2.9 2 1 1 3 3 3 0 BAG domain LMBR1 PF04791.16 KFM61318.1 - 1.7 7.5 8.1 2 7.2 8.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein O-antigen_lig PF13425.6 KFM61318.1 - 1.9 7.2 6.0 2.1 7.1 6.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein E2F_CC-MB PF16421.5 KFM61318.1 - 3.1 8.2 9.1 6.7 7.2 1.4 2.3 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF733 PF05306.11 KFM61318.1 - 8.1 6.8 16.2 1.6e+03 -0.5 16.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF733) Spore_II_R PF09551.10 KFM61318.1 - 8.5 6.8 8.2 2.7 8.5 4.5 1.9 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) TMPIT PF07851.13 KFM61318.1 - 9.9 5.3 10.1 13 4.9 10.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein HECT PF00632.25 KFM61319.1 - 3.6e-96 322.3 0.0 9.2e-96 320.9 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KFM61319.1 - 0.0012 18.4 0.2 0.0032 17.1 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif HSP20 PF00011.21 KFM61320.1 - 1.4e-27 95.8 0.2 2e-27 95.3 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFM61320.1 - 0.00072 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 KFM61321.1 - 1.4e-26 92.6 0.8 1.7e-26 92.3 0.8 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFM61321.1 - 2.6e-06 27.5 0.1 4.3e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal ArsA_HSP20 PF17886.1 KFM61321.1 - 1.2e-05 24.7 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 KFM61322.1 - 6.3e-28 96.9 0.4 7.7e-28 96.6 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFM61322.1 - 2.8e-08 33.8 0.7 5.7e-08 32.8 0.7 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal ArsA_HSP20 PF17886.1 KFM61322.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 HSP20-like domain found in ArsA CABIT PF12736.7 KFM61323.1 - 9.9e-08 31.6 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, EMP70 PF02990.16 KFM61324.1 - 8.8e-40 136.8 0.2 1.1e-39 136.5 0.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 EMP70 PF02990.16 KFM61325.1 - 1.3e-67 228.7 22.7 1.3e-67 228.7 22.7 1.5 2 0 0 2 2 2 1 Endomembrane protein 70 EF-hand_7 PF13499.6 KFM61326.1 - 1.9e-10 41.1 5.5 9.4e-10 38.8 2.8 2.1 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM61326.1 - 8.5e-09 34.4 5.8 0.00095 18.6 0.8 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFM61326.1 - 1.1e-07 31.6 5.5 2.6e-05 24.0 1.2 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM61326.1 - 1.3e-07 30.9 5.4 0.00011 21.9 2.1 3.6 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 KFM61326.1 - 0.018 15.0 1.4 0.024 14.6 0.2 1.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFM61326.1 - 0.069 13.5 0.1 0.28 11.5 0.1 1.8 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 KFM61326.1 - 0.35 10.4 4.0 8.9 6.0 0.7 2.6 2 0 0 2 2 2 0 EF hand Dimer_Tnp_hAT PF05699.14 KFM61327.1 - 6.1e-11 42.0 0.2 1.4e-10 40.8 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KFM61327.1 - 0.00082 19.7 0.2 0.0036 17.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) zf-BED PF02892.15 KFM61327.1 - 0.0017 18.4 0.6 0.0017 18.4 0.6 2.1 2 0 0 2 2 2 1 BED zinc finger DBD_Tnp_Hermes PF10683.9 KFM61327.1 - 0.011 15.5 0.0 0.05 13.3 0.0 2.2 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain SNF PF00209.18 KFM61330.1 - 5.8e-212 705.0 30.8 6.8e-212 704.8 30.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family GST_N_3 PF13417.6 KFM61331.1 - 1.2e-17 64.1 0.0 2.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFM61331.1 - 1.2e-12 48.0 0.0 2.9e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFM61331.1 - 9.8e-09 35.4 0.1 1.8e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFM61331.1 - 8.7e-06 25.9 0.1 1.7e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM61331.1 - 1.4e-05 25.2 0.2 3.1e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM61331.1 - 0.00078 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cytochrom_B558a PF05038.13 KFM61332.1 - 1.1e-39 136.0 0.1 1.2e-39 135.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit Cg6151-P PF10233.9 KFM61332.1 - 0.008 16.5 6.5 0.15 12.3 6.5 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 KFM61332.1 - 0.014 15.2 4.9 0.033 13.9 4.9 1.6 1 1 0 1 1 1 0 Transmembrane protein family 72 DUF4668 PF15701.5 KFM61332.1 - 0.08 12.8 0.1 0.094 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) COPI_assoc PF08507.10 KFM61332.1 - 0.45 10.6 7.2 1.1 9.4 7.2 1.6 1 1 0 1 1 1 0 COPI associated protein Cyclin_C PF02984.19 KFM61333.1 - 8.6e-15 54.9 0.0 9.3e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KFM61334.1 - 1.6e-32 111.9 0.1 2.2e-32 111.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Lipase PF00151.19 KFM61335.1 - 2.5e-79 267.0 0.0 3.3e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFM61335.1 - 6.9e-07 30.1 0.2 1.2e-06 29.3 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 KFM61335.1 - 0.00019 21.0 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 KFM61335.1 - 0.0022 17.7 0.3 0.0074 16.0 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KFM61335.1 - 0.022 14.6 0.0 0.087 12.7 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 3) PLAT PF01477.23 KFM61335.1 - 0.041 14.5 0.0 0.076 13.6 0.0 1.4 1 0 0 1 1 1 0 PLAT/LH2 domain Lipase PF00151.19 KFM61336.1 - 3.1e-44 151.7 0.0 3.6e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_1 PF00561.20 KFM61336.1 - 0.003 17.3 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM61336.1 - 0.0044 17.7 0.0 0.005 17.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM61336.1 - 0.0088 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2235 PF09994.9 KFM61336.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) LIDHydrolase PF10230.9 KFM61336.1 - 0.072 12.6 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase PF00151.19 KFM61337.1 - 0.001 18.5 0.5 0.0011 18.4 0.5 1.0 1 0 0 1 1 1 1 Lipase tRNA-synt_1e PF01406.19 KFM61338.1 - 1.3e-125 418.7 0.6 2e-125 418.2 0.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFM61338.1 - 4.5e-06 25.7 1.4 0.0045 15.8 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 KFM61338.1 - 0.001 18.1 0.0 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF445 PF04286.12 KFM61338.1 - 0.0034 17.2 8.7 0.0073 16.2 2.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF445) Ins_P5_2-kin PF06090.12 KFM61338.1 - 0.061 12.8 0.1 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Inositol-pentakisphosphate 2-kinase WD40 PF00400.32 KFM61339.1 - 2.8e-05 24.8 1.6 0.18 12.7 0.1 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM61339.1 - 0.033 14.5 0.0 19 5.6 0.0 3.3 1 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM61339.1 - 0.092 12.1 0.0 0.23 10.8 0.0 1.5 1 1 0 1 1 1 0 WD40-like domain LSM PF01423.22 KFM61340.1 - 9.3e-15 54.1 0.5 1.2e-14 53.7 0.5 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFM61340.1 - 0.0068 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Hfq protein NgoMIV_restric PF09015.10 KFM61340.1 - 0.079 12.1 0.0 0.079 12.1 0.0 1.0 1 0 0 1 1 1 0 NgoMIV restriction enzyme RNA_pol_3_Rpc31 PF11705.8 KFM61341.1 - 9.1e-19 68.6 9.0 1.4e-18 68.0 9.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PBP_sp32 PF07222.12 KFM61341.1 - 0.056 12.9 7.8 0.058 12.8 7.8 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF268 PF03269.14 KFM61341.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 AAA_23 PF13476.6 KFM61341.1 - 0.25 11.8 9.9 0.32 11.5 9.9 1.1 1 0 0 1 1 1 0 AAA domain CSRNP_N PF16019.5 KFM61341.1 - 2.8 7.8 5.7 3.6 7.4 5.7 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus OATP PF03137.20 KFM61341.1 - 3.4 5.8 4.4 4.4 5.5 4.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family OATP PF03137.20 KFM61342.1 - 8.4e-144 479.8 15.9 9.6e-144 479.6 15.9 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFM61342.1 - 1.6e-16 60.2 30.6 1.6e-16 60.2 30.6 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFM61342.1 - 4e-08 33.3 11.9 4e-08 33.3 11.9 1.8 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM61342.1 - 0.00096 19.1 10.6 0.0023 17.9 10.6 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain UNC-93 PF05978.16 KFM61342.1 - 0.013 15.2 0.9 0.013 15.2 0.9 2.6 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 SH PF01445.17 KFM61342.1 - 0.11 12.5 0.2 0.28 11.2 0.2 1.7 1 0 0 1 1 1 0 Viral small hydrophobic protein DDE_3 PF13358.6 KFM61343.1 - 7e-06 25.9 0.0 1.2e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease SPATA19 PF15212.6 KFM61343.1 - 0.013 15.8 0.2 0.02 15.1 0.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial ADH_N PF08240.12 KFM61344.1 - 2.6e-24 85.2 2.0 6.2e-24 84.0 2.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM61344.1 - 5.6e-23 81.3 0.0 9.3e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM61344.1 - 0.0058 17.7 0.0 0.01 16.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFM61344.1 - 0.0082 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM61344.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFM61344.1 - 0.023 15.0 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Kinesin PF00225.23 KFM61347.1 - 2e-08 33.6 0.0 9.5e-08 31.3 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFM61347.1 - 4.8e-06 26.6 0.0 7.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding DDE_3 PF13358.6 KFM61350.1 - 9.4e-11 41.7 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease IGR PF09597.10 KFM61351.1 - 0.063 13.4 0.4 0.084 13.0 0.4 1.2 1 0 0 1 1 1 0 IGR protein motif NHL PF01436.21 KFM61352.1 - 1.6e-36 122.5 15.8 1.7e-10 40.4 0.1 6.3 6 0 0 6 6 6 5 NHL repeat zf-B_box PF00643.24 KFM61352.1 - 1.1e-08 35.0 8.1 1.1e-08 35.0 8.1 3.9 4 1 0 4 4 2 2 B-box zinc finger zf-RING_UBOX PF13445.6 KFM61352.1 - 1.3e-08 34.7 11.6 1.3e-08 34.7 11.6 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM61352.1 - 5.8e-08 32.5 13.9 5.8e-08 32.5 13.9 3.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 KFM61352.1 - 8e-08 32.2 0.1 0.06 12.9 0.1 3.3 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 KFM61352.1 - 3.8e-06 26.3 12.1 4.6e-05 22.7 0.2 3.7 3 1 1 4 4 4 2 6-bladed beta-propeller zf-RING_5 PF14634.6 KFM61352.1 - 1.1e-05 25.3 11.9 1.1e-05 25.3 11.9 3.6 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM61352.1 - 6.2e-05 22.8 14.0 6.2e-05 22.8 14.0 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM61352.1 - 0.0004 20.7 12.3 0.0004 20.7 12.3 3.6 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFM61352.1 - 0.0044 17.1 12.4 0.0044 17.1 12.4 3.5 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFM61352.1 - 0.0068 16.2 13.7 0.0068 16.2 13.7 3.4 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 DUF3583 PF12126.8 KFM61352.1 - 0.0096 15.4 0.7 0.014 14.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) PRA-PH PF01503.17 KFM61352.1 - 0.014 15.8 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase CHU_C PF13585.6 KFM61352.1 - 0.019 15.0 2.1 7 6.8 0.0 4.1 4 0 0 4 4 4 0 C-terminal domain of CHU protein family BLOC1_2 PF10046.9 KFM61352.1 - 0.28 11.5 3.3 2 8.7 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HTH_Tnp_Tc5 PF03221.16 KFM61353.1 - 3.3e-12 46.2 0.4 6.2e-12 45.4 0.4 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KFM61353.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM61353.1 - 0.0023 17.7 0.0 0.0055 16.5 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 KFM61353.1 - 0.091 13.1 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Transposase DUF3372 PF11852.8 KFM61353.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) MH2 PF03166.14 KFM61359.1 - 5.8e-79 264.6 0.2 9e-79 264.0 0.2 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFM61359.1 - 3.7e-42 142.7 0.3 7.4e-42 141.8 0.3 1.5 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFM61359.1 - 0.0024 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 RXLR_WY PF18634.1 KFM61359.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain VASt PF16016.5 KFM61360.1 - 0.0016 18.8 1.6 0.41 11.0 0.1 2.3 1 1 1 2 2 2 2 VAD1 Analog of StAR-related lipid transfer domain Pro-MCH PF05824.12 KFM61360.1 - 0.0063 16.4 0.0 3.8 7.5 0.0 2.6 2 1 0 2 2 2 2 Pro-melanin-concentrating hormone (Pro-MCH) PLU-1 PF08429.11 KFM61363.1 - 3.3e-92 309.3 21.5 1.7e-89 300.3 15.8 2.7 2 0 0 2 2 2 2 PLU-1-like protein PHD PF00628.29 KFM61363.1 - 6e-16 58.1 16.8 3.9e-08 33.1 4.5 2.7 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 KFM61363.1 - 0.0097 16.1 11.1 0.028 14.6 2.6 2.8 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFM61363.1 - 0.25 11.5 9.3 0.65 10.2 1.5 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 KFM61363.1 - 0.48 10.8 14.5 0.7 10.3 1.8 2.6 2 0 0 2 2 2 0 Ring finger domain C1_1 PF00130.22 KFM61363.1 - 7.4 6.6 8.9 2 8.4 2.8 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CW PF07496.15 KFM61363.1 - 8 6.6 9.6 0.84 9.7 1.4 2.7 2 0 0 2 2 2 0 CW-type Zinc Finger PHD PF00628.29 KFM61365.1 - 2.2e-14 53.1 4.5 4.3e-14 52.1 4.5 1.5 1 0 0 1 1 1 1 PHD-finger JmjC PF02373.22 KFM61365.1 - 2.7e-09 37.5 1.2 5.9e-09 36.4 1.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-PHD-like PF15446.6 KFM61365.1 - 0.0055 16.3 2.4 0.012 15.3 2.2 1.7 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 KFM61365.1 - 0.39 10.9 5.9 1.6 8.9 5.9 2.1 1 1 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 KFM61365.1 - 3.1 7.4 6.3 0.22 11.1 0.5 2.1 2 0 0 2 2 2 0 PHD-finger ARID PF01388.21 KFM61366.1 - 7e-20 71.5 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KFM61366.1 - 5.9e-17 61.3 1.3 1.1e-16 60.4 1.3 1.5 1 0 0 1 1 1 1 jmjN domain G-patch PF01585.23 KFM61366.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 G-patch domain eIF-3c_N PF05470.12 KFM61367.1 - 5.4e-223 741.6 27.7 2.2e-222 739.6 26.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KFM61367.1 - 1.6e-13 51.1 2.6 1.7e-13 51.0 0.3 2.3 2 0 0 2 2 2 1 PCI domain RVT_1 PF00078.27 KFM61368.1 - 3.1e-37 128.3 0.0 4.5e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med3 PF11593.8 KFM61372.1 - 7.6 5.6 17.9 8 5.5 17.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DBC1 PF14443.6 KFM61373.1 - 2.4e-46 156.7 0.0 4.3e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 DBC1 DUF2457 PF10446.9 KFM61373.1 - 0.15 11.2 10.2 0.21 10.7 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SAP PF02037.27 KFM61374.1 - 1.5e-09 37.4 1.0 3e-09 36.4 1.0 1.6 1 0 0 1 1 1 1 SAP domain Ctr PF04145.15 KFM61374.1 - 9.7 6.8 0.0 9.7 6.8 0.0 3.5 2 2 0 3 3 3 0 Ctr copper transporter family BK_channel_a PF03493.18 KFM61375.1 - 3.8e-38 129.6 0.0 7.5e-38 128.7 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 KFM61375.1 - 0.014 15.6 0.1 2.8 8.2 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain Ion_trans_2 PF07885.16 KFM61376.1 - 2.4e-17 62.7 3.7 3.8e-17 62.0 3.7 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFM61376.1 - 4.7e-09 35.8 1.5 6.4e-09 35.4 1.5 1.2 1 0 0 1 1 1 1 Ion transport protein PMP1_2 PF08114.11 KFM61376.1 - 0.009 15.7 0.8 0.021 14.6 0.8 1.6 1 0 0 1 1 1 1 ATPase proteolipid family Pkinase PF00069.25 KFM61377.1 - 3.8e-45 154.3 0.0 4.6e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM61377.1 - 9.5e-16 57.8 0.0 1.5e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM61377.1 - 0.0012 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFM61377.1 - 0.021 14.8 0.0 0.099 12.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM61377.1 - 0.048 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFM61378.1 - 1.8e-05 24.2 0.2 1.9e-05 24.2 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KFM61380.1 - 3.2e-83 274.4 39.5 4.6e-14 52.8 4.2 15.6 9 4 7 16 16 16 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM61380.1 - 4.9e-70 231.1 31.8 1.4e-08 35.1 0.0 19.8 12 5 9 22 22 22 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM61380.1 - 1.8e-57 190.6 26.2 1.5e-05 25.2 0.1 16.9 11 5 6 18 18 18 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM61380.1 - 1.1e-52 169.8 37.4 0.00014 22.0 0.0 24.6 26 0 0 26 26 26 12 Ankyrin repeat Ank PF00023.30 KFM61380.1 - 6.2e-47 156.1 58.1 5.5e-06 26.6 0.1 24.5 27 2 0 27 27 27 12 Ankyrin repeat Ras PF00071.22 KFM61381.1 - 7.6e-56 188.2 0.0 8.6e-56 188.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM61381.1 - 3.3e-21 75.7 0.0 6.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM61381.1 - 1e-07 31.6 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM61381.1 - 0.001 18.7 0.0 0.0031 17.1 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Serpin PF00079.20 KFM61382.1 - 1.1e-26 94.0 0.1 1.2e-26 93.9 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Myb_DNA-bind_2 PF08914.11 KFM61382.1 - 0.034 14.3 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Rap1 Myb domain RhoGAP PF00620.27 KFM61384.1 - 2.8e-24 85.7 3.0 8.7e-24 84.1 1.4 2.0 2 0 0 2 2 2 1 RhoGAP domain GUCT PF08152.12 KFM61384.1 - 0.094 13.0 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 GUCT (NUC152) domain Rib_5-P_isom_A PF06026.14 KFM61386.1 - 4.1e-60 202.3 0.0 5.5e-60 201.9 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KFM61386.1 - 0.00081 19.4 0.1 0.017 15.0 0.2 2.2 2 0 0 2 2 2 1 DeoR C terminal sensor domain Sugar-bind PF04198.13 KFM61386.1 - 0.017 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Kazal_2 PF07648.15 KFM61387.1 - 8.8e-16 57.8 34.7 2.4e-08 34.0 5.5 4.8 3 1 1 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM61387.1 - 4.8e-06 26.5 44.8 4.5e-05 23.4 3.8 5.4 4 2 1 5 5 5 3 Kazal-type serine protease inhibitor domain Zn-C2H2_12 PF18112.1 KFM61387.1 - 1.8 9.1 7.3 13 6.4 0.1 4.6 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain 2-Hacid_dh_C PF02826.19 KFM61389.1 - 2.4e-58 196.4 0.0 9.4e-58 194.5 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFM61389.1 - 3e-38 130.5 0.0 4.2e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFM61389.1 - 0.00042 20.5 0.0 0.0093 16.1 0.0 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFM61389.1 - 0.001 18.6 0.0 0.0046 16.5 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KFM61389.1 - 0.1 12.7 1.1 0.5 10.4 0.0 2.4 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain zf-H2C2_2 PF13465.6 KFM61390.1 - 6.7e-26 89.5 47.8 4.9e-09 36.2 0.2 6.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM61390.1 - 1.7e-14 53.3 50.8 6.4e-07 29.5 3.5 5.5 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61390.1 - 6.5e-14 51.5 44.6 0.00022 21.8 1.0 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM61390.1 - 6.7e-07 29.2 42.8 5.8e-05 23.0 1.4 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 KFM61390.1 - 2.1e-06 27.9 42.3 0.0064 16.8 1.2 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM61390.1 - 0.00058 20.1 11.9 0.0081 16.4 3.2 5.0 3 1 2 5 5 5 3 Zinc-finger double-stranded RNA-binding Baculo_IE-1 PF05290.11 KFM61390.1 - 0.13 12.2 14.2 0.079 12.9 6.0 2.5 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) GAGA PF09237.11 KFM61390.1 - 0.57 10.0 15.0 0.85 9.5 0.2 3.7 1 1 3 4 4 4 0 GAGA factor zf-C2H2_4 PF13894.6 KFM61391.1 - 1.4e-11 44.2 4.2 7.8e-05 23.2 0.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM61391.1 - 2.2e-11 43.5 6.3 4.7e-05 23.6 0.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM61391.1 - 3e-10 39.8 2.7 3.7e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM61391.1 - 3.2e-10 40.0 3.6 6e-06 26.4 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KFM61391.1 - 2.3e-07 30.9 2.6 0.0011 19.3 0.1 2.3 2 1 0 2 2 2 2 Zinc-finger of C2H2 type zf-MYST PF17772.1 KFM61391.1 - 0.00051 19.6 2.2 0.026 14.1 0.1 2.1 1 1 1 2 2 2 1 MYST family zinc finger domain zf-SNAP50_C PF12251.8 KFM61391.1 - 0.0025 17.5 1.5 0.0026 17.5 1.5 1.0 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C2HC_2 PF13913.6 KFM61391.1 - 0.003 17.4 0.6 0.8 9.7 0.0 2.6 2 1 0 2 2 2 1 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFM61391.1 - 0.0032 17.2 3.2 1.1 9.1 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM61391.1 - 0.005 17.1 2.8 1.4 9.3 0.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) HNH PF01844.23 KFM61391.1 - 0.0075 16.4 0.8 2.8 8.2 0.1 2.1 2 0 0 2 2 2 2 HNH endonuclease zf-UBP_var PF17807.1 KFM61391.1 - 0.0095 15.7 0.2 0.016 15.0 0.1 1.5 1 1 1 2 2 2 1 Variant UBP zinc finger zf-Di19 PF05605.12 KFM61391.1 - 0.012 15.9 1.2 0.017 15.4 1.2 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KFM61391.1 - 0.017 14.9 0.8 3.8 7.4 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-FCS PF06467.14 KFM61391.1 - 0.018 15.0 1.3 0.12 12.3 1.5 1.9 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_11 PF16622.5 KFM61391.1 - 0.022 14.5 3.6 0.25 11.1 0.8 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type GAGA PF09237.11 KFM61391.1 - 0.038 13.8 0.0 9.1 6.2 0.0 2.1 1 1 1 2 2 2 0 GAGA factor zf-C2H2_3rep PF18868.1 KFM61391.1 - 0.046 14.4 1.5 3 8.5 0.1 2.0 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 KFM61391.1 - 0.048 14.0 1.2 0.052 13.9 1.2 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-RING_11 PF17123.5 KFM61391.1 - 0.067 13.0 0.3 3.4 7.5 0.0 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-BED PF02892.15 KFM61391.1 - 0.19 11.8 4.9 2.1 8.4 0.5 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 KFM61391.1 - 0.2 12.0 2.7 14 6.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met2 PF12907.7 KFM61391.1 - 0.96 9.6 5.0 6.6 7.0 0.2 2.5 2 2 0 2 2 2 0 Zinc-binding zf-HIT PF04438.16 KFM61391.1 - 3.9 7.4 8.7 3.2 7.7 0.2 2.5 3 0 0 3 3 3 0 HIT zinc finger Gemini_mov PF01708.16 KFM61392.1 - 0.041 13.7 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein Insulin_TMD PF17870.1 KFM61392.1 - 0.097 12.8 1.0 0.19 11.8 1.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SERTA PF06031.13 KFM61393.1 - 3.7e-11 42.5 1.0 9.6e-11 41.2 1.0 1.8 1 0 0 1 1 1 1 SERTA motif Phage_TTP_1 PF04630.12 KFM61393.1 - 0.12 11.6 1.8 0.28 10.5 1.8 1.5 1 0 0 1 1 1 0 Phage tail tube protein Frizzled PF01534.17 KFM61394.1 - 4e-136 453.3 21.0 5.2e-136 453.0 21.0 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFM61394.1 - 1.4e-33 115.8 3.4 3.6e-33 114.5 3.4 1.7 1 0 0 1 1 1 1 Fz domain EGF PF00008.27 KFM61396.1 - 2.8e-31 107.4 84.8 2.3e-07 31.0 11.5 6.3 6 0 0 6 6 6 5 EGF-like domain EGF_2 PF07974.13 KFM61396.1 - 1.4e-13 50.9 92.1 0.011 16.0 8.4 6.3 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.7 KFM61396.1 - 3.4e-09 37.0 69.2 0.0027 18.3 7.7 6.9 6 0 0 6 6 6 4 Human growth factor-like EGF EGF_3 PF12947.7 KFM61396.1 - 8.9e-07 29.0 83.4 0.018 15.2 5.4 6.6 5 1 1 6 6 6 5 EGF domain EGF_CA PF07645.15 KFM61396.1 - 0.00016 21.8 94.3 0.0046 17.1 11.3 6.6 2 2 4 6 6 6 5 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 KFM61396.1 - 3.3 8.1 86.1 0.12 12.7 8.2 6.8 6 1 1 7 7 7 0 Pvs28 EGF domain EF-hand_1 PF00036.32 KFM61398.1 - 4.7e-15 53.9 1.3 0.00011 21.4 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFM61398.1 - 8.4e-13 48.6 3.8 1.7e-08 34.8 0.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM61398.1 - 8.9e-13 47.1 0.5 0.014 15.3 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFM61398.1 - 4.2e-12 45.0 0.7 0.00095 18.6 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFM61398.1 - 1.9e-08 34.0 1.0 0.14 12.0 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM61398.1 - 0.00043 20.6 1.8 0.014 15.7 0.6 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFM61398.1 - 0.016 15.4 0.3 15 5.9 0.0 3.0 3 0 0 3 3 3 0 Dockerin type I domain EF-hand_4 PF12763.7 KFM61398.1 - 0.021 14.8 2.5 1.9 8.5 0.1 3.1 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KFM61398.1 - 0.14 13.1 0.2 0.36 11.7 0.1 1.7 1 1 1 2 2 2 0 EF-hand domain FG-GAP PF01839.23 KFM61398.1 - 4.8 7.4 5.9 8.4 6.6 0.1 3.0 3 0 0 3 3 3 0 FG-GAP repeat Aa_trans PF01490.18 KFM61399.1 - 1.3e-74 251.4 29.2 1.5e-74 251.2 29.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ras PF00071.22 KFM61400.1 - 1.5e-46 157.9 0.3 1.7e-46 157.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM61400.1 - 2.9e-17 63.0 0.0 4.6e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM61400.1 - 9e-08 31.8 0.0 9.7e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM61400.1 - 1.3e-06 28.1 0.1 7.2e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM61400.1 - 2.5e-05 24.3 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM61400.1 - 0.0021 18.0 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KFM61400.1 - 0.004 17.0 0.2 0.0091 15.8 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KFM61400.1 - 0.0059 16.1 0.1 0.012 15.1 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RNase_T PF00929.24 KFM61401.1 - 1.4e-08 35.4 0.0 4.3e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 KFM61401.1 - 7.8e-07 29.5 0.0 7.8e-07 29.5 0.0 2.1 3 0 0 3 3 3 1 ElonginA binding-protein 1 CbiC PF02570.15 KFM61401.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Precorrin-8X methylmutase Cse1 PF08506.10 KFM61402.1 - 2.2e-142 474.3 6.6 2.8e-142 473.9 6.6 1.1 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 KFM61402.1 - 2.4e-48 164.7 0.7 2.4e-47 161.4 0.1 2.5 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus DUF3385 PF11865.8 KFM61402.1 - 0.0026 17.7 0.5 0.23 11.3 0.0 3.2 3 1 0 4 4 4 1 Domain of unknown function (DUF3385) Phyto_Pns9_10 PF05878.11 KFM61402.1 - 0.021 14.0 0.1 0.035 13.3 0.1 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF1340 PF07067.11 KFM61402.1 - 0.094 12.1 0.2 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1340) DUF913 PF06025.12 KFM61403.1 - 0.2 10.6 7.3 0.24 10.4 7.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) IBN_N PF03810.19 KFM61404.1 - 3.7e-12 46.0 0.0 1.1e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFM61404.1 - 0.002 18.2 0.0 0.0057 16.7 0.0 1.7 2 0 0 2 2 2 1 Exportin 1-like protein TUDOR PF00567.24 KFM61405.1 - 1.3e-140 461.1 20.9 9.9e-32 109.5 0.2 6.5 6 0 0 6 6 6 6 Tudor domain Agenet PF05641.12 KFM61405.1 - 1.4e-10 41.5 7.6 0.0052 17.2 0.2 6.7 7 0 0 7 7 7 3 Agenet domain SMN PF06003.12 KFM61405.1 - 8e-09 35.1 1.1 0.29 10.4 0.1 5.8 6 0 0 6 6 6 3 Survival motor neuron protein (SMN) DUF4537 PF15057.6 KFM61405.1 - 3.2e-05 23.9 1.2 1.4 9.0 0.0 4.9 5 0 0 5 5 5 2 Domain of unknown function (DUF4537) UPF0228 PF05727.11 KFM61405.1 - 0.051 13.4 1.4 39 4.1 0.0 3.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0228) Tudor-knot PF11717.8 KFM61405.1 - 0.18 11.7 7.5 25 4.9 0.1 5.7 7 0 0 7 7 7 0 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 KFM61405.1 - 5.8 6.7 5.5 22 4.9 0.1 4.0 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain TUDOR PF00567.24 KFM61406.1 - 2.2e-135 444.2 13.2 3e-27 95.1 0.1 7.7 7 0 0 7 7 7 7 Tudor domain DUF4537 PF15057.6 KFM61406.1 - 2.4e-05 24.4 0.1 0.76 9.8 0.0 5.0 5 0 0 5 5 5 2 Domain of unknown function (DUF4537) Tudor-knot PF11717.8 KFM61406.1 - 5.4e-05 23.0 2.1 53 3.8 0.0 6.5 7 0 0 7 7 7 0 RNA binding activity-knot of a chromodomain Agenet PF05641.12 KFM61406.1 - 0.00042 20.7 14.5 0.79 10.2 0.3 8.0 8 1 0 8 8 8 2 Agenet domain tRNA_int_endo PF01974.17 KFM61406.1 - 0.14 12.3 0.3 2.3 8.4 0.0 3.0 3 0 0 3 3 3 0 tRNA intron endonuclease, catalytic C-terminal domain Sushi PF00084.20 KFM61407.1 - 2.4e-110 361.1 71.3 1e-12 48.4 0.8 11.7 11 1 0 11 11 11 11 Sushi repeat (SCR repeat) HRM PF02793.22 KFM61407.1 - 1.5e-18 66.8 57.8 0.03 14.6 0.4 11.5 11 0 0 11 11 11 9 Hormone receptor domain Lectin_C PF00059.21 KFM61407.1 - 7e-11 42.8 0.1 7e-11 42.8 0.1 2.9 3 0 0 3 3 3 1 Lectin C-type domain F5_F8_type_C PF00754.25 KFM61407.1 - 8.2e-07 29.2 0.0 4.2e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain Terminase_GpA PF05876.12 KFM61407.1 - 0.0044 15.6 8.4 0.031 12.8 0.1 4.5 3 1 0 5 5 5 1 Phage terminase large subunit (GpA) Mid2 PF04478.12 KFM61407.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 KFM61407.1 - 0.033 13.6 3.1 0.066 12.6 3.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Orthoreo_P10 PF07204.11 KFM61407.1 - 0.066 13.2 1.4 0.11 12.4 0.3 1.9 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 TMEM51 PF15345.6 KFM61407.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Glycophorin_A PF01102.18 KFM61407.1 - 0.21 11.9 0.3 0.42 10.9 0.3 1.4 1 0 0 1 1 1 0 Glycophorin A Adeno_E3_CR2 PF02439.15 KFM61407.1 - 1.4 8.8 6.4 2.9 7.7 6.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FAM183 PF14886.6 KFM61408.1 - 0.0024 18.6 0.1 0.0059 17.3 0.0 1.8 1 1 1 2 2 2 1 FAM183A and FAM183B related Collagen PF01391.18 KFM61410.1 - 2.8e-08 33.4 11.7 3e-08 33.3 11.7 1.0 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Dimer_Tnp_hAT PF05699.14 KFM61412.1 - 1.3e-11 44.2 0.0 3.3e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KFM61412.1 - 4.4e-07 29.9 1.0 0.0075 16.1 0.5 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Propep_M14 PF02244.16 KFM61412.1 - 0.84 10.1 5.0 4.1 7.9 0.7 3.2 4 0 0 4 4 4 0 Carboxypeptidase activation peptide DEAD PF00270.29 KFM61415.1 - 2.2e-49 167.6 0.0 4.1e-49 166.7 0.0 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM61415.1 - 1.2e-08 35.2 0.0 8.3e-08 32.6 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM61415.1 - 1.4e-07 31.7 0.0 2.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFM61415.1 - 0.0015 18.3 0.0 0.006 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF2608 PF11019.8 KFM61415.1 - 0.0068 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2608) Terminase_6 PF03237.15 KFM61415.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Terminase-like family FAA_hydrolase PF01557.18 KFM61417.1 - 1.9e-11 44.0 0.1 2.1e-11 43.9 0.1 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase PF01557.18 KFM61418.1 - 1.2e-37 129.7 0.0 1.6e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KFM61418.1 - 6.3e-31 106.7 0.0 1.1e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Ras PF00071.22 KFM61419.1 - 4.6e-52 175.9 0.1 5.6e-52 175.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM61419.1 - 2.2e-31 108.6 0.0 3.4e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM61419.1 - 4.2e-14 52.4 0.0 6.1e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM61419.1 - 5.3e-05 22.8 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM61419.1 - 0.00054 19.9 0.1 0.4 10.6 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFM61419.1 - 0.0058 16.1 0.0 0.0089 15.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFM61419.1 - 0.025 13.9 0.1 0.049 13.0 0.1 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KFM61419.1 - 0.093 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 KFM61420.1 - 9.2e-58 196.1 1.2 1e-57 195.9 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFM61420.1 - 9.9e-10 38.1 0.1 3e-09 36.6 0.1 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family L_lactis_RepB_C PF06430.12 KFM61420.1 - 0.061 13.3 0.1 0.095 12.7 0.1 1.2 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus Pet100 PF09803.9 KFM61421.1 - 3e-27 94.9 2.4 3.4e-27 94.7 2.4 1.0 1 0 0 1 1 1 1 Pet100 CLP1_P PF16575.5 KFM61422.1 - 1.5e-55 187.9 0.0 4.6e-55 186.3 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KFM61422.1 - 4.9e-22 77.9 0.1 8.4e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KFM61422.1 - 3.7e-18 66.1 0.1 5.9e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CbiA PF01656.23 KFM61422.1 - 0.00083 19.4 0.0 0.0011 19.0 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 KFM61422.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KFM61422.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFM61422.1 - 0.015 15.4 0.0 0.048 13.8 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KFM61422.1 - 0.042 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KFM61422.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_10 PF12846.7 KFM61422.1 - 0.14 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain CLP1_P PF16575.5 KFM61423.1 - 8.7e-56 188.7 0.0 1.6e-55 187.8 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KFM61423.1 - 8.1e-22 77.8 0.1 1.4e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 KFM61423.1 - 5.3e-17 61.8 0.1 1e-16 60.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor MMR_HSR1 PF01926.23 KFM61423.1 - 0.00042 20.4 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase CbiA PF01656.23 KFM61423.1 - 0.00091 19.3 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 KFM61423.1 - 0.0059 16.5 0.6 0.053 13.4 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase ATPase PF06745.13 KFM61423.1 - 0.012 15.0 0.0 0.072 12.4 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.6 KFM61423.1 - 0.037 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM61423.1 - 0.037 14.4 0.0 0.064 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFM61423.1 - 0.041 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CAP_C PF08603.11 KFM61423.1 - 0.069 12.8 0.2 0.069 12.8 0.2 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal AAA_25 PF13481.6 KFM61423.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 KFM61424.1 - 7.4e-41 138.0 0.1 2.4e-21 75.5 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein zf-C2H2 PF00096.26 KFM61425.1 - 6.9e-16 57.7 25.6 3e-06 27.4 4.4 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM61425.1 - 4.1e-13 49.1 9.2 6.9e-09 35.7 1.5 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM61425.1 - 1e-08 35.3 25.6 0.0005 20.7 2.3 4.3 4 0 0 4 4 3 3 C2H2-type zinc finger DUF3850 PF12961.7 KFM61425.1 - 0.047 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) zf-C2H2_6 PF13912.6 KFM61425.1 - 0.062 13.3 1.0 0.062 13.3 1.0 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM61425.1 - 0.12 12.7 9.3 2.3 8.6 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 KFM61425.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.3 1 1 2 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FOXP-CC PF16159.5 KFM61425.1 - 0.16 12.6 9.2 5.6 7.7 2.7 3.3 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KFM61425.1 - 0.22 12.2 7.9 0.9 10.3 2.4 2.8 1 1 1 2 2 2 0 TRAF-type zinc finger KRE9 PF05390.11 KFM61425.1 - 0.27 12.0 8.6 0.79 10.5 0.6 2.5 1 1 1 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 zf-H2C2_5 PF13909.6 KFM61425.1 - 0.51 10.1 0.1 0.51 10.1 0.1 5.1 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM61425.1 - 1.2 9.1 6.1 1.4 8.9 0.3 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFM61425.1 - 1.5 9.2 8.5 0.46 10.8 0.6 2.8 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ogr_Delta PF04606.12 KFM61425.1 - 5.7 7.0 15.2 4.8 7.2 0.2 3.9 2 1 2 4 4 4 0 Ogr/Delta-like zinc finger DHR-2 PF06920.13 KFM61426.1 - 1.6e-50 172.3 0.1 2.4e-50 171.7 0.1 1.2 1 0 0 1 1 1 1 Dock homology region 2 DHR-2 PF06920.13 KFM61427.1 - 5.7e-24 84.7 3.8 9.9e-23 80.6 3.8 1.9 1 1 0 1 1 1 1 Dock homology region 2 HEPN_RiboL-PSP PF18735.1 KFM61427.1 - 0.059 13.3 0.1 0.068 13.1 0.1 1.1 1 0 0 1 1 1 0 RiboL-PSP-HEPN SH3BGR PF04908.15 KFM61428.1 - 9.9e-36 121.9 0.2 9.9e-36 121.9 0.2 1.5 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KFM61428.1 - 0.0021 18.2 0.0 0.0039 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin TFIID-18kDa PF02269.16 KFM61429.1 - 2e-19 69.4 1.1 4.5e-19 68.3 0.3 2.1 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit EF-hand_1 PF00036.32 KFM61430.1 - 3.7e-26 88.7 10.0 2.8e-08 32.8 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFM61430.1 - 5.4e-25 87.6 3.5 4.6e-13 49.4 0.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM61430.1 - 1.4e-20 71.4 6.5 8.8e-08 31.5 0.3 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFM61430.1 - 1.3e-19 68.7 5.2 4.9e-06 25.8 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFM61430.1 - 2.5e-17 62.5 11.8 1.1e-11 44.4 1.3 3.9 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM61430.1 - 5.9e-10 39.5 0.6 6.7e-06 26.4 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFM61430.1 - 1.5e-06 28.4 0.2 0.02 15.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFM61430.1 - 9.1e-05 22.4 3.4 0.0017 18.2 0.4 2.6 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 KFM61430.1 - 0.00074 19.6 0.1 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_14 PF17959.1 KFM61430.1 - 0.0028 17.9 0.4 0.012 15.9 0.2 2.1 1 1 1 2 2 2 1 EF-hand domain DUF5580 PF17743.1 KFM61430.1 - 0.024 13.2 0.0 0.77 8.2 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 KFM61430.1 - 0.035 14.3 4.5 3.6 7.8 0.1 2.7 2 2 0 2 2 2 0 Dockerin type I domain EF-hand_10 PF14788.6 KFM61430.1 - 0.047 13.6 1.1 0.22 11.4 0.1 2.4 2 1 1 3 3 3 0 EF hand DUF1848 PF08902.11 KFM61430.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) HELP PF03451.14 KFM61433.1 - 1e-31 108.6 0.2 2.3e-31 107.5 0.2 1.6 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 KFM61433.1 - 6.3e-19 68.0 13.0 0.0006 20.6 0.3 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM61433.1 - 0.0027 18.0 0.2 2.2 8.7 0.0 4.5 4 3 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PKcGMP_CC PF16808.5 KFM61433.1 - 0.033 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fib_alpha PF08702.10 KFM61433.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 KFM61434.1 - 3.4e-09 37.2 7.3 4.7e-05 24.1 0.9 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Toxin_18 PF08087.11 KFM61435.1 - 0.053 13.5 6.4 0.053 13.5 6.4 4.1 3 2 1 4 4 4 0 Conotoxin O-superfamily Squash PF00299.18 KFM61435.1 - 0.22 11.6 0.4 0.22 11.6 0.4 3.6 3 1 0 3 3 3 0 Squash family serine protease inhibitor Dickkopf_N PF04706.12 KFM61435.1 - 0.27 11.7 0.5 0.27 11.7 0.5 3.4 1 1 2 3 3 3 0 Dickkopf N-terminal cysteine-rich region DX PF01666.17 KFM61435.1 - 1.8 9.1 22.2 1.5 9.3 2.7 3.2 2 1 1 3 3 3 0 DX module Acyl_transf_3 PF01757.22 KFM61437.1 - 3.1e-06 26.5 10.6 3.4e-06 26.4 10.6 1.1 1 0 0 1 1 1 1 Acyltransferase family FA_desaturase PF00487.24 KFM61437.1 - 0.36 10.6 9.3 4.3 7.1 5.9 2.0 1 1 1 2 2 2 0 Fatty acid desaturase Acyl_transf_3 PF01757.22 KFM61438.1 - 0.016 14.3 0.9 0.016 14.3 0.9 1.0 1 0 0 1 1 1 0 Acyltransferase family DUF4817 PF16087.5 KFM61439.1 - 0.00059 19.6 0.0 0.0029 17.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 KFM61439.1 - 0.0087 16.7 1.3 0.027 15.1 1.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 KFM61440.1 - 1.5e-14 54.0 0.0 1.4e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM61440.1 - 1.3e-09 38.1 0.0 2.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Transposase EGF PF00008.27 KFM61441.1 - 7.1e-153 496.2 514.1 1.4e-07 31.7 6.4 36.4 35 2 0 35 35 35 33 EGF-like domain hEGF PF12661.7 KFM61441.1 - 5.4e-82 267.9 417.5 3.6e-06 27.4 1.2 36.3 35 0 0 35 35 35 31 Human growth factor-like EGF Laminin_G_2 PF02210.24 KFM61441.1 - 2e-37 128.6 7.4 2.5e-12 47.5 0.0 4.8 4 1 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.23 KFM61441.1 - 2.7e-32 111.7 0.6 1.8e-08 34.7 0.0 4.9 4 1 0 4 4 4 4 Laminin G domain EGF_2 PF07974.13 KFM61441.1 - 2.5e-16 59.7 560.2 0.014 15.8 12.6 34.9 34 0 0 34 34 34 22 EGF-like domain EGF_CA PF07645.15 KFM61441.1 - 8.3e-10 38.7 543.3 9.1e-06 25.8 6.3 36.1 24 8 12 36 36 32 18 Calcium-binding EGF domain Laminin_G_3 PF13385.6 KFM61441.1 - 1.8e-08 34.7 1.4 1.2e-05 25.6 0.1 2.7 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Plasmod_Pvs28 PF06247.11 KFM61441.1 - 0.00067 19.9 2.8 0.00067 19.9 2.8 32.9 27 7 4 31 31 26 4 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 KFM61441.1 - 0.0015 18.6 4.0 0.0015 18.6 4.0 29.5 30 1 1 31 31 23 3 MSP1 EGF domain 1 EGF_3 PF12947.7 KFM61441.1 - 0.0028 17.8 7.3 0.0028 17.8 7.3 35.9 28 5 7 35 35 35 13 EGF domain TMEM154 PF15102.6 KFM61441.1 - 0.0029 17.5 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family cEGF PF12662.7 KFM61441.1 - 0.0064 16.4 1.9 0.0064 16.4 1.9 33.2 36 2 0 36 36 31 10 Complement Clr-like EGF-like RuvC_1 PF18516.1 KFM61441.1 - 0.14 11.3 0.1 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 RuvC nuclease domain DUF3377 PF11857.8 KFM61441.1 - 0.16 11.9 0.1 0.43 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Trypsin PF00089.26 KFM61442.1 - 4.5e-67 226.1 0.2 5.5e-67 225.8 0.2 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM61442.1 - 5.3e-07 30.0 0.0 9.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFM61442.1 - 7.1e-07 30.2 0.0 1.1e-06 29.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KFM61442.1 - 0.0063 16.1 0.0 0.17 11.5 0.0 2.1 2 0 0 2 2 2 1 Chymotrypsin family Peptidase-S1 Trypsin PF00089.26 KFM61443.1 - 4.7e-35 121.4 0.0 6.2e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM61443.1 - 6.3e-05 23.3 0.0 0.00011 22.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFM61443.1 - 0.00016 22.6 0.0 0.00023 22.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain FAM76 PF16046.5 KFM61444.1 - 0.087 12.2 1.2 0.088 12.1 1.2 1.0 1 0 0 1 1 1 0 FAM76 protein Homeodomain PF00046.29 KFM61445.1 - 1.9e-10 40.4 1.4 3.3e-10 39.7 1.4 1.4 1 0 0 1 1 1 1 Homeodomain Fasciclin PF02469.22 KFM61446.1 - 0.05 13.8 0.0 0.052 13.8 0.0 1.1 1 0 0 1 1 1 0 Fasciclin domain Arginosuc_synth PF00764.19 KFM61447.1 - 4.7e-76 256.6 0.0 5.3e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Peptidase_S51 PF03575.17 KFM61448.1 - 1.8e-19 70.2 0.0 2e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S51 A_deaminase PF00962.22 KFM61449.1 - 2.4e-38 132.3 0.0 2.7e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-C2H2 PF00096.26 KFM61451.1 - 6.1e-23 79.9 47.7 3.7e-05 24.0 3.1 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM61451.1 - 1.5e-18 66.3 39.3 7.3e-06 26.2 1.0 6.5 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM61451.1 - 2.5e-16 58.9 40.1 0.0048 17.6 1.7 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM61451.1 - 1.4e-08 34.5 37.4 4.9e-05 23.2 2.4 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM61451.1 - 2.6e-05 24.4 25.3 0.14 12.5 1.4 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM61451.1 - 0.00018 21.7 29.3 0.023 15.1 0.7 5.3 5 0 0 5 5 5 3 Zinc-finger of C2H2 type C1_4 PF07975.12 KFM61451.1 - 0.00021 21.4 23.1 0.011 16.0 3.9 3.6 2 1 2 4 4 4 2 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KFM61451.1 - 0.0021 18.2 22.4 0.14 12.2 2.5 4.0 2 1 2 4 4 4 4 Zinc ribbon domain zf-C2HE PF16278.5 KFM61451.1 - 0.022 15.2 1.2 0.022 15.2 1.2 4.8 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KFM61451.1 - 0.045 13.9 28.9 0.48 10.6 3.3 5.4 4 1 1 5 5 5 0 AN1-like Zinc finger DZR PF12773.7 KFM61451.1 - 0.41 10.7 17.4 2.2e+03 -1.2 17.4 3.0 1 1 0 1 1 1 0 Double zinc ribbon DUF2256 PF10013.9 KFM61451.1 - 1 9.5 0.1 1 9.5 0.1 4.9 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 KFM61451.1 - 1.3 8.9 13.7 0.26 11.1 0.4 4.1 1 1 3 4 4 4 0 GAGA factor YhfH PF14149.6 KFM61451.1 - 1.4 9.0 9.0 27 4.9 0.0 3.5 3 0 0 3 3 3 0 YhfH-like protein zinc_ribbon_15 PF17032.5 KFM61451.1 - 3.6 8.4 16.4 0.71 10.7 1.9 3.2 1 1 2 3 3 3 0 zinc-ribbon family zf-trcl PF13451.6 KFM61451.1 - 5.4 7.0 21.9 12 5.9 1.8 5.1 5 0 0 5 5 5 0 Probable zinc-ribbon domain DUF2072 PF09845.9 KFM61451.1 - 6.8 7.0 8.8 2.7 8.2 0.2 3.2 3 0 0 3 3 3 0 Zn-ribbon containing protein XPA_N PF01286.18 KFM61451.1 - 7.1 6.8 23.6 3.6 7.7 0.6 5.9 7 0 0 7 7 6 0 XPA protein N-terminal DUF3268 PF11672.8 KFM61451.1 - 9.4 6.6 9.1 20 5.5 0.6 3.1 3 1 0 3 3 3 0 zinc-finger-containing domain IQ PF00612.27 KFM61452.1 - 0.01 15.6 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif RVT_1 PF00078.27 KFM61453.1 - 3.8e-42 144.3 0.3 5.7e-42 143.7 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PKD_channel PF08016.12 KFM61454.1 - 3.8e-99 332.3 12.2 7e-99 331.4 12.2 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFM61454.1 - 7.2e-15 54.9 26.1 7.2e-15 54.9 26.1 2.5 2 0 0 2 2 2 1 Ion transport protein OATP PF03137.20 KFM61454.1 - 0.00028 19.3 0.0 0.00028 19.3 0.0 2.6 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF4328 PF14219.6 KFM61454.1 - 0.055 13.0 0.1 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) PLAT PF01477.23 KFM61455.1 - 6.9e-10 39.5 0.0 1.4e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain GPS PF01825.21 KFM61455.1 - 2.4e-07 31.2 1.7 4.5e-07 30.3 1.7 1.4 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif REJ PF02010.15 KFM61457.1 - 1.3e-10 40.7 0.0 1.5e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 REJ domain REJ PF02010.15 KFM61458.1 - 3.5e-14 52.5 0.0 2e-13 49.9 0.0 1.8 1 1 0 2 2 2 1 REJ domain PKD PF00801.20 KFM61460.1 - 2.2e-12 46.7 0.0 4.6e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 PKD domain YtkA PF13115.6 KFM61460.1 - 0.075 13.6 0.2 0.27 11.9 0.0 2.0 2 0 0 2 2 2 0 YtkA-like CK2S PF15011.6 KFM61463.1 - 0.00012 22.0 2.0 0.00024 21.1 1.5 1.6 1 1 0 1 1 1 1 Casein Kinase 2 substrate PAS_11 PF14598.6 KFM61465.1 - 1.8e-06 28.0 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KFM61465.1 - 2.2e-06 27.8 0.0 4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold Cyclin_N2 PF16500.5 KFM61465.1 - 0.095 13.5 0.0 0.13 13.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal region of cyclin_N PAS PF00989.25 KFM61466.1 - 0.16 11.9 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 PAS fold zf-H2C2_2 PF13465.6 KFM61468.1 - 1.7e-11 44.0 26.7 4.1e-07 30.1 2.0 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM61468.1 - 1.9e-09 37.4 29.2 0.00042 20.6 3.1 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61468.1 - 2.6e-07 30.9 26.6 0.0027 18.4 2.6 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM61468.1 - 0.00013 21.8 5.9 0.051 13.5 0.8 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFM61468.1 - 0.044 13.8 7.0 2 8.5 1.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KFM61468.1 - 0.1 13.3 10.0 3.8 8.2 1.1 3.9 2 1 2 4 4 4 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 KFM61468.1 - 0.99 9.1 7.6 1.3 8.7 0.7 2.8 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 KFM61468.1 - 8.9 6.7 14.4 0.15 12.3 3.2 2.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Syntaxin_2 PF14523.6 KFM61469.1 - 1.1e-29 102.8 14.4 1.4e-29 102.4 9.3 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KFM61469.1 - 3.1e-15 55.9 0.9 3.1e-15 55.9 0.9 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KFM61469.1 - 8.7e-09 35.3 13.4 7.1e-08 32.4 13.4 2.2 1 1 0 1 1 1 1 Syntaxin TMF_TATA_bd PF12325.8 KFM61469.1 - 0.0038 17.4 1.2 0.0038 17.4 1.2 3.3 2 2 1 3 3 3 1 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.6 KFM61469.1 - 0.016 13.9 6.1 0.25 10.0 0.5 2.0 2 0 0 2 2 2 0 AAA domain DUF4988 PF16378.5 KFM61469.1 - 0.031 14.0 2.3 0.079 12.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function Synaptobrevin PF00957.21 KFM61469.1 - 0.049 13.4 0.6 0.049 13.4 0.6 3.1 3 0 0 3 3 3 0 Synaptobrevin DUF948 PF06103.11 KFM61469.1 - 0.07 13.4 0.2 0.07 13.4 0.2 2.8 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) HsbA PF12296.8 KFM61469.1 - 0.096 13.1 2.4 0.13 12.7 0.2 2.1 2 1 0 2 2 2 0 Hydrophobic surface binding protein A ISG65-75 PF11727.8 KFM61469.1 - 0.37 10.0 7.8 1.2 8.4 1.2 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Tropomyosin_1 PF12718.7 KFM61469.1 - 0.38 10.9 11.3 0.05 13.7 3.3 2.3 2 1 0 2 2 2 0 Tropomyosin like MCPsignal PF00015.21 KFM61469.1 - 0.41 10.4 9.6 0.15 11.8 1.6 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.12 KFM61469.1 - 0.54 10.8 8.4 0.2 12.1 1.5 2.7 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MIF4G_like_2 PF09090.11 KFM61469.1 - 0.62 9.5 7.0 10 5.5 0.1 2.4 2 1 0 2 2 2 0 MIF4G like MCU PF04678.13 KFM61469.1 - 1.6 8.8 8.9 1 9.5 1.0 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF883 PF05957.13 KFM61469.1 - 3.6 8.2 13.7 0.55 10.9 1.4 3.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Sulfatase_C PF14707.6 KFM61469.1 - 5.5 7.7 5.5 5.2 7.8 0.4 2.8 2 2 1 3 3 3 0 C-terminal region of aryl-sulfatase RRM_1 PF00076.22 KFM61470.1 - 8.5e-25 86.4 0.1 9.4e-13 47.8 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trnau1ap PF17654.1 KFM61470.1 - 1.5e-14 54.7 30.5 3.6e-14 53.5 28.9 2.3 1 1 1 2 2 2 1 Selenocysteine tRNA 1 associated proteins Ndufs5 PF10200.9 KFM61471.1 - 1.5e-06 28.4 2.5 1.8e-06 28.1 2.5 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 KFM61471.1 - 0.029 14.4 6.3 0.057 13.4 6.1 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like EF-1_beta_acid PF10587.9 KFM61471.1 - 0.38 11.2 3.8 0.84 10.1 3.8 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Integrase_H2C2 PF17921.1 KFM61472.1 - 2.6e-11 43.4 0.3 3.4e-11 43.1 0.3 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM61472.1 - 0.029 14.6 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 H2C2 zinc finger RNB PF00773.19 KFM61473.1 - 2.9e-101 339.0 0.1 1.1e-100 337.2 0.0 1.9 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 KFM61473.1 - 3.7e-26 91.0 0.0 8.7e-26 89.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KFM61473.1 - 2.1e-19 69.6 0.0 8.1e-19 67.7 0.0 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 KFM61473.1 - 8.6e-09 35.3 0.0 3.1e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 KFM61473.1 - 1.9e-05 24.8 0.0 0.039 14.1 0.0 3.4 3 0 0 3 3 3 2 Cold shock domain OB_RNB PF08206.11 KFM61473.1 - 0.0053 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain Ig_2 PF13895.6 KFM61473.1 - 0.058 13.7 0.1 0.21 11.9 0.1 2.0 1 0 0 1 1 1 0 Immunoglobulin domain GD_N PF16030.5 KFM61473.1 - 0.065 13.5 0.7 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 Serine protease gd N-terminus DXP_redisom_C PF08436.12 KFM61473.1 - 0.066 13.4 0.1 0.22 11.7 0.1 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Aminotran_1_2 PF00155.21 KFM61474.1 - 4.8e-69 233.3 0.0 5.5e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFM61474.1 - 6e-05 21.7 0.0 8.6e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFM61474.1 - 0.00018 20.6 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFM61474.1 - 0.0025 17.2 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFM61474.1 - 0.0088 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 KFM61474.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Aminotran_3 PF00202.21 KFM61474.1 - 0.053 12.2 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III eIF2A PF08662.11 KFM61475.1 - 4.4e-49 167.0 2.6 4.4e-49 167.0 2.6 2.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFM61475.1 - 0.011 16.0 0.6 1.4 9.2 0.0 3.9 4 2 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 KFM61475.1 - 0.063 12.0 0.4 0.41 9.4 0.1 2.5 2 2 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region BioW PF03744.13 KFM61475.1 - 0.097 12.2 0.4 0.16 11.5 0.4 1.3 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase Lig_chan PF00060.26 KFM61479.1 - 9.9e-41 139.0 0.0 1.2e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Ligand-gated ion channel Ion_trans_2 PF07885.16 KFM61479.1 - 3.3e-06 27.0 0.1 6.9e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 Ion channel TMEM252 PF15664.5 KFM61480.1 - 0.016 14.9 0.9 0.017 14.8 0.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 252 family CYYR1 PF10873.8 KFM61480.1 - 0.061 13.8 1.0 0.07 13.6 1.0 1.1 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 TMEM52 PF14979.6 KFM61480.1 - 0.082 12.8 1.3 0.092 12.7 1.3 1.2 1 1 0 1 1 1 0 Transmembrane 52 EB PF01683.18 KFM61481.1 - 0.00021 21.5 2.3 0.00029 21.1 2.3 1.3 1 0 0 1 1 1 1 EB module Plasmod_Pvs28 PF06247.11 KFM61481.1 - 0.0076 16.5 8.4 0.082 13.2 8.5 2.5 1 1 1 2 2 2 1 Pvs28 EGF domain EGF_3 PF12947.7 KFM61481.1 - 0.27 11.5 5.5 1.3 9.3 5.5 2.0 1 1 0 1 1 1 0 EGF domain HRM PF02793.22 KFM61482.1 - 5.8e-15 55.3 9.0 1e-14 54.5 9.0 1.4 1 0 0 1 1 1 1 Hormone receptor domain DUF936 PF06075.12 KFM61483.1 - 0.0035 16.3 0.5 0.004 16.1 0.5 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) PBC PF03792.13 KFM61484.1 - 1.3e-45 155.5 0.0 1.4e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 PBC domain Sec15 PF04091.12 KFM61484.1 - 0.011 15.2 0.5 0.013 14.9 0.5 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like LZ3wCH PF18517.1 KFM61484.1 - 0.051 13.7 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Leucine zipper with capping helix domain DUF3391 PF11871.8 KFM61484.1 - 0.053 14.1 0.1 0.064 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Peptidase_C97 PF05903.14 KFM61484.1 - 0.08 12.8 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain LIM_bind PF01803.16 KFM61485.1 - 2.2e-59 200.9 2.0 1.1e-57 195.3 0.1 2.5 2 1 0 2 2 2 1 LIM-domain binding protein LID PF17916.1 KFM61485.1 - 1.6e-15 56.4 3.2 3.1e-15 55.5 3.2 1.5 1 0 0 1 1 1 1 LIM interaction domain (LID) Vinculin PF01044.19 KFM61486.1 - 1.7e-66 225.2 4.1 1.9e-66 225.0 4.1 1.0 1 0 0 1 1 1 1 Vinculin family I_LWEQ PF01608.17 KFM61486.1 - 0.00019 21.7 2.7 0.00069 19.9 2.7 1.7 1 1 0 1 1 1 1 I/LWEQ domain DUF1495 PF07381.11 KFM61486.1 - 0.023 14.5 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) FCH PF00611.23 KFM61486.1 - 0.091 13.1 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Phage_int_SAM_4 PF13495.6 KFM61486.1 - 0.13 12.8 0.1 0.63 10.6 0.0 2.2 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Vinculin PF01044.19 KFM61487.1 - 1.9e-22 79.4 0.2 2.1e-22 79.3 0.2 1.0 1 0 0 1 1 1 1 Vinculin family Vinculin PF01044.19 KFM61488.1 - 6.9e-120 401.9 14.6 1.3e-96 324.9 5.9 2.5 1 1 1 2 2 2 2 Vinculin family GIT1_C PF12205.8 KFM61488.1 - 0.013 15.6 4.0 0.1 12.8 0.2 2.9 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term VBS PF08913.10 KFM61488.1 - 0.09 13.2 0.3 0.41 11.1 0.1 2.2 2 0 0 2 2 2 0 Vinculin Binding Site DUF5344 PF17279.2 KFM61488.1 - 0.56 10.8 6.1 2.9 8.6 0.2 3.5 4 1 0 4 4 4 0 Family of unknown function (DUF5344) YtxH PF12732.7 KFM61488.1 - 3.2 8.4 10.6 1.8 9.1 0.3 4.1 3 2 0 3 3 3 0 YtxH-like protein FUSC PF04632.12 KFM61488.1 - 3.2 6.2 6.7 2.2 6.7 0.8 2.1 1 1 2 3 3 3 0 Fusaric acid resistance protein family G-alpha PF00503.20 KFM61490.1 - 8.2e-41 140.3 0.0 9.3e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFM61490.1 - 0.022 14.2 0.2 0.081 12.4 0.1 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_24 PF13479.6 KFM61490.1 - 0.036 13.8 0.1 0.046 13.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain Herpes_BBRF1 PF04793.12 KFM61490.1 - 0.043 12.8 0.0 0.08 12.0 0.0 1.5 1 0 0 1 1 1 0 BRRF1-like protein Roc PF08477.13 KFM61490.1 - 0.046 13.9 0.2 0.075 13.2 0.1 1.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFM61490.1 - 0.059 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KFM61490.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SID PF11778.8 KFM61490.1 - 0.094 12.8 1.2 1.6 8.8 1.2 2.2 1 1 0 1 1 1 0 Septation initiation Cast PF10174.9 KFM61491.1 - 2.7e-39 135.1 31.7 8.2e-37 126.9 23.9 2.9 1 1 1 2 2 2 2 RIM-binding protein of the cytomatrix active zone DASH_Spc34 PF08657.10 KFM61491.1 - 0.042 13.6 15.7 0.14 11.9 15.8 1.8 1 1 0 1 1 1 0 DASH complex subunit Spc34 Fib_alpha PF08702.10 KFM61491.1 - 0.69 10.1 18.7 0.52 10.5 9.6 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 KFM61491.1 - 1.3 8.1 26.4 0.37 9.8 20.1 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KFM61491.1 - 4 7.5 29.9 0.12 12.5 7.6 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2570 PF10828.8 KFM61491.1 - 6.1 6.7 20.6 0.91 9.4 6.4 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) DUF16 PF01519.16 KFM61491.1 - 6.5 7.3 21.4 28 5.3 11.7 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF641 PF04859.12 KFM61491.1 - 8.9 6.7 29.9 12 6.3 0.8 4.0 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 KFM61491.1 - 9.5 5.5 14.6 28 4.0 14.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BAT2_N PF07001.11 KFM61493.1 - 0.074 13.5 0.0 0.078 13.4 0.0 1.0 1 0 0 1 1 1 0 BAT2 N-terminus zf-H2C2_2 PF13465.6 KFM61495.1 - 1.4e-34 117.0 38.5 2.2e-06 27.9 0.2 7.5 7 1 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM61495.1 - 3.6e-34 115.3 54.4 5.4e-06 26.6 2.4 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-met PF12874.7 KFM61495.1 - 4.3e-26 90.5 41.7 7.6e-05 23.0 1.0 6.2 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM61495.1 - 9.9e-22 75.8 46.6 0.00074 20.2 2.2 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM61495.1 - 8.7e-19 67.3 33.2 0.001 19.3 0.8 6.2 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM61495.1 - 3.6e-07 30.0 38.8 0.21 11.6 0.5 7.5 7 0 0 7 7 7 4 C2H2-type zinc finger BolA PF01722.18 KFM61495.1 - 9.5e-06 25.8 8.6 0.41 11.0 0.4 4.7 1 1 3 4 4 4 3 BolA-like protein zf-H2C2_5 PF13909.6 KFM61495.1 - 0.00011 21.8 31.7 0.018 14.8 0.4 5.9 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM61495.1 - 0.00096 19.0 27.3 1.1 9.2 0.2 5.8 5 1 1 6 6 6 4 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM61495.1 - 0.0065 16.0 23.5 2.2 8.0 0.6 5.9 5 1 1 6 6 6 2 MYST family zinc finger domain Zn_ribbon_SprT PF17283.2 KFM61495.1 - 0.032 14.2 0.3 0.032 14.2 0.3 4.3 2 1 3 5 5 5 0 SprT-like zinc ribbon domain zf-RRPl_C4 PF17026.5 KFM61495.1 - 0.088 12.9 21.5 0.89 9.7 11.5 3.4 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Zf_RING PF16744.5 KFM61495.1 - 0.13 12.4 26.6 1.4 9.1 3.7 5.7 1 1 4 5 5 5 0 KIAA1045 RING finger zf-C2H2_11 PF16622.5 KFM61495.1 - 0.19 11.5 0.5 0.19 11.5 0.5 5.2 6 0 0 6 6 6 0 zinc-finger C2H2-type DUF2256 PF10013.9 KFM61495.1 - 0.19 11.8 18.6 11 6.3 0.1 6.0 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KFM61495.1 - 0.24 11.8 34.1 4.6 7.6 12.4 5.1 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFM61495.1 - 0.37 11.0 18.7 1.5 9.0 1.1 4.2 3 3 1 4 4 4 0 Zinc ribbon domain zf-BED PF02892.15 KFM61495.1 - 0.42 10.7 41.0 0.3 11.1 1.4 5.7 1 1 5 6 6 6 0 BED zinc finger ADK_lid PF05191.14 KFM61495.1 - 0.99 9.4 19.5 22 5.1 0.6 4.5 2 2 1 3 3 3 0 Adenylate kinase, active site lid zinc-ribbons_6 PF07191.12 KFM61495.1 - 1.9 8.5 20.7 28 4.8 1.6 4.8 1 1 3 4 4 4 0 zinc-ribbons zinc_ribbon_15 PF17032.5 KFM61495.1 - 2.3 9.0 20.6 1.4 9.7 2.1 3.2 1 1 3 4 4 4 0 zinc-ribbon family GAGA PF09237.11 KFM61495.1 - 7.2 6.5 15.1 0.68 9.8 0.1 3.8 1 1 3 5 5 5 0 GAGA factor HLH PF00010.26 KFM61497.1 - 1.2e-17 63.6 1.0 1.2e-17 63.6 1.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFM61497.1 - 0.084 12.8 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain AIF_C PF14721.6 KFM61498.1 - 1.9e-56 190.0 0.0 3.3e-56 189.2 0.0 1.4 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.14 KFM61498.1 - 9.3e-45 153.1 0.0 1.6e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM61498.1 - 1e-14 54.8 0.2 1.8e-12 47.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM61498.1 - 1.7e-11 43.9 0.1 8.3e-11 41.7 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFM61498.1 - 1.1e-06 28.5 1.2 0.049 13.2 0.0 3.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFM61498.1 - 4.4e-05 23.5 0.9 0.056 13.4 0.0 3.5 2 1 1 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KFM61498.1 - 0.00013 21.2 0.1 0.052 12.7 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KFM61498.1 - 0.00046 19.0 3.8 0.0039 15.9 0.0 2.9 3 1 1 4 4 4 1 HI0933-like protein GIDA PF01134.22 KFM61498.1 - 0.003 16.7 1.9 1.3 8.1 0.1 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KFM61498.1 - 0.022 14.0 0.0 0.075 12.3 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HHV6-IE PF03753.13 KFM61498.1 - 0.11 9.9 0.0 0.17 9.4 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Ank_2 PF12796.7 KFM61499.1 - 5.2e-53 177.6 9.9 1.1e-16 61.2 0.5 6.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KFM61499.1 - 1.3e-45 151.9 12.9 1.1e-07 32.0 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 KFM61499.1 - 4.2e-44 148.4 9.0 3.1e-11 43.6 0.2 7.5 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM61499.1 - 8.2e-40 130.3 20.1 3.5e-05 23.9 0.1 10.5 11 1 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 KFM61499.1 - 6.9e-32 109.1 12.7 3e-07 30.6 0.0 8.1 4 1 4 8 8 8 7 Ankyrin repeats (many copies) TPR_12 PF13424.6 KFM61499.1 - 0.00023 21.4 0.0 0.059 13.7 0.0 3.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM61499.1 - 0.0012 18.7 0.6 0.31 11.0 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM61499.1 - 0.032 14.1 0.6 1.4 8.9 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM61499.1 - 0.058 13.5 3.5 0.61 10.3 0.8 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Rad60-SLD PF11976.8 KFM61501.1 - 0.024 14.4 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like GDA1_CD39 PF01150.17 KFM61502.1 - 1.2e-65 221.9 3.2 2.1e-65 221.1 3.2 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4083 PF13314.6 KFM61502.1 - 0.066 13.2 1.7 0.16 12.0 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Ppx-GppA PF02541.16 KFM61502.1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Sigma_reg_N PF13800.6 KFM61502.1 - 0.25 11.7 1.4 0.61 10.4 1.1 1.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal PDZ PF00595.24 KFM61503.1 - 1.9e-14 53.7 1.6 2.6e-14 53.3 1.6 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM61503.1 - 5.9e-10 38.8 0.8 9.1e-10 38.2 0.8 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM61503.1 - 0.00089 19.5 0.1 0.0012 19.1 0.1 1.2 1 0 0 1 1 1 1 PDZ domain T2SSE_N PF05157.15 KFM61503.1 - 0.02 15.1 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain DUF4371 PF14291.6 KFM61504.1 - 6.8e-10 39.0 0.0 2.1e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) HTH_48 PF17906.1 KFM61504.1 - 0.00014 21.9 1.0 0.00059 19.9 1.0 2.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase zf-C2H2_12 PF18658.1 KFM61504.1 - 0.0029 17.1 0.4 0.0029 17.1 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger C2H2-type HTH_24 PF13412.6 KFM61504.1 - 0.025 14.1 0.2 0.35 10.5 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 KFM61504.1 - 0.071 13.1 2.4 0.34 10.9 0.3 2.5 2 0 0 2 2 2 0 HTH domain HTH_32 PF13565.6 KFM61504.1 - 0.086 13.5 0.1 0.24 12.1 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 KFM61504.1 - 0.15 11.9 0.4 13 5.7 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Noc2 PF03715.13 KFM61506.1 - 8.4e-111 370.0 7.9 8.4e-111 370.0 7.9 1.4 2 0 0 2 2 2 1 Noc2p family PAZ PF02170.22 KFM61507.1 - 0.054 13.3 0.1 0.071 12.9 0.1 1.2 1 0 0 1 1 1 0 PAZ domain XPA_C PF05181.12 KFM61508.1 - 2.3e-21 75.5 0.4 4.5e-21 74.6 0.4 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KFM61508.1 - 2.2e-13 50.0 5.2 2.2e-13 50.0 5.2 2.0 2 0 0 2 2 2 1 XPA protein N-terminal DUF5082 PF16888.5 KFM61508.1 - 0.014 15.6 0.9 0.014 15.6 0.9 2.3 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) ADD_DNMT3 PF17980.1 KFM61508.1 - 0.082 12.9 0.1 0.082 12.9 0.1 2.4 2 1 1 3 3 3 0 Cysteine rich ADD domain in DNMT3 Aldedh PF00171.22 KFM61509.1 - 5.1e-121 404.4 0.1 6e-121 404.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 KFM61509.1 - 0.095 12.7 0.6 0.26 11.3 0.1 1.8 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Kinesin PF00225.23 KFM61511.1 - 7.3e-100 334.1 0.0 8.6e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM61511.1 - 7.5e-24 84.4 0.0 1.4e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Phospholip_A2_2 PF05826.12 KFM61512.1 - 1.8e-35 121.1 4.7 1.8e-35 121.1 4.7 1.8 2 0 0 2 2 2 1 Phospholipase A2 PLA2G12 PF06951.11 KFM61512.1 - 0.015 15.2 4.7 0.045 13.7 3.8 2.1 2 1 0 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) Miff PF05644.11 KFM61512.1 - 0.17 11.5 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Phospholip_A2_1 PF00068.19 KFM61512.1 - 1.2 9.6 9.4 62 4.1 9.6 2.7 1 1 0 1 1 1 0 Phospholipase A2 Med13_C PF06333.12 KFM61514.1 - 7.8e-78 262.0 0.2 7.8e-78 262.0 0.2 1.7 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 KFM61514.1 - 1.4e-64 218.3 0.4 3.1e-63 213.9 0.1 2.2 2 0 0 2 2 2 1 MID domain of medPIWI Chitin_bind_4 PF00379.23 KFM61518.1 - 2.9e-11 43.7 6.1 4.3e-11 43.2 6.1 1.3 1 0 0 1 1 1 1 Insect cuticle protein DUF959 PF06121.14 KFM61518.1 - 0.023 15.0 2.9 0.031 14.5 2.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) Fibrinogen_C PF00147.18 KFM61519.1 - 1.7e-63 214.4 12.5 2.2e-63 214.0 12.5 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain COLFI PF01410.18 KFM61519.1 - 6.7e-05 22.3 0.2 0.00011 21.6 0.2 1.4 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Fibrinogen_C PF00147.18 KFM61520.1 - 1.3e-58 198.4 15.0 2.1e-58 197.8 15.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Trypsin PF00089.26 KFM61520.1 - 7.3e-26 91.3 0.2 1.2e-25 90.6 0.2 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM61520.1 - 7.6e-07 30.1 0.0 1.5e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain COLFI PF01410.18 KFM61520.1 - 5.8e-05 22.5 0.4 9.4e-05 21.8 0.4 1.4 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain DUF444 PF04285.12 KFM61521.1 - 0.073 12.1 0.1 0.089 11.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF444) F_actin_bind PF08919.10 KFM61522.1 - 2.1e-31 108.2 0.2 8e-31 106.4 0.2 2.0 1 0 0 1 1 1 1 F-actin binding TSC22 PF01166.18 KFM61524.1 - 0.0055 17.0 1.4 0.018 15.4 0.8 2.0 2 0 0 2 2 2 1 TSC-22/dip/bun family Lebercilin PF15619.6 KFM61524.1 - 0.0075 16.0 1.1 0.022 14.4 0.4 1.8 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease GIT_CC PF16559.5 KFM61524.1 - 0.06 13.2 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 KFM61524.1 - 0.061 13.1 0.4 0.087 12.6 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator ABC_tran_CTD PF16326.5 KFM61524.1 - 0.069 13.4 1.1 0.14 12.4 1.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain PCI PF01399.27 KFM61526.1 - 0.035 14.6 0.1 0.039 14.5 0.1 1.1 1 0 0 1 1 1 0 PCI domain Sigma70_r1_1 PF03979.14 KFM61526.1 - 0.15 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 DDE_1 PF03184.19 KFM61528.1 - 1.2e-29 103.2 0.3 2e-29 102.5 0.3 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM61528.1 - 4.1e-11 42.7 0.2 4.1e-11 42.7 0.2 2.2 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain BrkDBD PF09607.10 KFM61528.1 - 5.5e-09 35.7 0.3 1.9e-08 34.0 0.3 1.9 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_1 PF01527.20 KFM61528.1 - 0.00076 19.8 3.1 0.00076 19.8 3.1 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM61528.1 - 0.0094 15.7 0.0 0.096 12.4 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease LolA PF03548.15 KFM61528.1 - 0.018 14.7 0.1 0.069 12.9 0.0 2.1 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA EGF PF00008.27 KFM61530.1 - 3.7e-29 100.7 79.1 6.3e-08 32.8 6.5 6.5 6 0 0 6 6 6 6 EGF-like domain EGF_2 PF07974.13 KFM61530.1 - 3.7e-09 36.8 86.9 0.004 17.5 7.6 6.2 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.7 KFM61530.1 - 0.034 14.8 74.1 0.52 11.0 1.9 7.4 7 0 0 7 7 7 0 Human growth factor-like EGF Laminin_EGF PF00053.24 KFM61530.1 - 9 6.5 75.7 6.3 7.0 7.7 6.2 1 1 5 6 6 6 0 Laminin EGF domain RIC3 PF15361.6 KFM61532.1 - 3.3e-20 72.9 0.2 4.9e-20 72.4 0.2 1.2 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 DUF2207 PF09972.9 KFM61532.1 - 0.18 10.6 0.1 2 7.1 0.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) ALG3 PF05208.13 KFM61533.1 - 3.7e-126 421.4 28.5 4.5e-126 421.1 28.5 1.1 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.6 KFM61533.1 - 0.061 12.6 40.3 0.09 12.1 40.3 1.2 1 0 0 1 1 1 0 EpsG family Antimicrobial_8 PF08103.11 KFM61534.1 - 0.024 14.7 0.9 1 9.7 0.1 2.9 2 0 0 2 2 2 0 Uperin family AA_kinase PF00696.28 KFM61535.1 - 3.8e-27 95.4 0.0 7.2e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 KFM61535.1 - 8.5e-17 60.8 0.1 2e-12 46.4 0.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family HSP70 PF00012.20 KFM61535.1 - 0.16 10.1 0.2 0.45 8.6 0.0 1.7 2 0 0 2 2 2 0 Hsp70 protein zf-H2C2_2 PF13465.6 KFM61536.1 - 2.5e-09 37.1 18.8 1.1e-07 31.9 4.2 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM61536.1 - 3.4e-08 33.5 20.9 3.2e-05 24.1 3.7 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61536.1 - 7.4e-07 29.5 14.1 5.1e-05 23.8 2.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM61536.1 - 2.3e-05 24.0 12.0 0.0034 17.1 0.6 2.4 2 1 0 2 2 2 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFM61536.1 - 0.0019 18.5 0.4 0.0019 18.5 0.4 2.5 3 1 0 3 3 3 1 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 KFM61536.1 - 0.0026 18.2 10.0 0.058 13.9 0.5 2.7 2 1 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_7 PF15269.6 KFM61536.1 - 0.015 15.4 2.0 0.015 15.4 2.0 2.1 1 1 1 2 2 2 0 Zinc-finger DUF2225 PF09986.9 KFM61536.1 - 0.04 13.6 0.6 0.04 13.6 0.6 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.12 KFM61536.1 - 0.081 13.2 6.7 0.16 12.3 6.2 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 KFM61536.1 - 0.16 11.9 6.5 1.7 8.6 6.5 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 KFM61536.1 - 0.23 11.5 6.6 1.2 9.2 6.6 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-H2C2_2 PF13465.6 KFM61537.1 - 1.4e-13 50.6 15.0 2.8e-08 33.8 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM61537.1 - 1.1e-11 44.5 17.2 0.00074 19.8 0.8 3.4 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM61537.1 - 5.8e-09 35.5 10.3 4.1e-06 26.4 0.7 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM61537.1 - 5.8e-09 36.0 14.6 0.02 15.7 0.8 3.4 3 1 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM61537.1 - 1.1e-06 28.8 7.1 0.011 16.1 0.3 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM61537.1 - 3.5e-05 24.0 4.2 0.029 14.7 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM61537.1 - 0.00015 22.1 7.5 0.0019 18.5 8.7 2.1 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFM61537.1 - 0.001 18.7 1.7 0.001 18.7 1.7 4.1 3 2 0 3 3 3 1 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 KFM61537.1 - 0.011 15.3 6.9 0.52 10.0 1.7 2.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain C1_1 PF00130.22 KFM61537.1 - 0.063 13.2 9.2 2.4 8.1 2.1 3.4 2 2 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2225 PF09986.9 KFM61537.1 - 0.089 12.5 6.4 1.9 8.1 3.1 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) OrsD PF12013.8 KFM61537.1 - 0.14 12.6 9.2 1.9 8.9 0.1 2.9 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D C1_4 PF07975.12 KFM61537.1 - 0.17 12.2 6.5 0.2 11.9 2.5 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_12 PF18658.1 KFM61537.1 - 0.39 10.3 10.4 0.14 11.7 1.3 2.9 1 1 2 3 3 3 0 Zinc-finger C2H2-type zf-C2HE PF16278.5 KFM61537.1 - 4.3 7.8 7.7 3.3 8.2 0.1 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 KFM61539.1 - 1.4e-10 41.1 11.6 1e-05 25.7 1.7 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM61539.1 - 7.1e-07 29.5 12.6 0.00024 21.7 4.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM61539.1 - 5.4e-05 23.4 14.4 0.00015 22.0 7.3 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM61539.1 - 0.00014 22.0 2.1 0.00014 22.0 2.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM61539.1 - 0.00022 21.5 10.7 0.0051 17.2 2.8 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.15 KFM61539.1 - 0.0029 17.6 2.3 0.0029 17.6 2.3 2.1 1 1 1 2 2 2 1 BED zinc finger zf-C2H2_2 PF12756.7 KFM61539.1 - 0.041 14.2 1.7 0.041 14.2 1.7 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2072 PF09845.9 KFM61539.1 - 0.062 13.6 1.3 0.062 13.6 0.8 1.3 1 1 0 1 1 1 0 Zn-ribbon containing protein DUF2256 PF10013.9 KFM61539.1 - 0.065 13.4 4.3 0.12 12.5 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) ATPase-cat_bd PF12156.8 KFM61539.1 - 0.075 13.8 3.1 0.085 13.6 3.1 1.1 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase DUF2197 PF09963.9 KFM61539.1 - 0.1 12.9 4.2 0.13 12.5 4.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf_UBZ PF18439.1 KFM61539.1 - 0.3 10.7 3.9 1.6 8.3 0.4 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 KFM61539.1 - 0.3 11.1 5.2 0.58 10.2 0.2 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2HE PF16278.5 KFM61539.1 - 4.3 7.9 8.6 0.58 10.6 3.1 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF629 PF04780.12 KFM61539.1 - 9.4 4.6 8.6 0.91 8.0 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Rad60-SLD PF11976.8 KFM61541.1 - 4.8e-17 61.5 1.2 4.9e-14 51.9 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFM61541.1 - 1.4e-08 34.3 0.3 7e-07 28.9 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L13 PF00572.18 KFM61542.1 - 2.5e-10 40.7 0.2 4.5e-08 33.4 0.0 2.9 2 1 0 2 2 2 1 Ribosomal protein L13 Pkinase PF00069.25 KFM61543.1 - 5.8e-72 242.2 0.0 7.1e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM61543.1 - 1.3e-31 109.9 0.0 1.7e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM61543.1 - 7.4e-09 35.0 0.7 1.1e-08 34.5 0.7 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM61543.1 - 0.0036 16.7 0.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFM61543.1 - 0.026 13.3 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Sec10 PF07393.11 KFM61544.1 - 1.7e-134 449.9 9.0 3.1e-131 439.1 9.0 3.0 1 1 0 1 1 1 1 Exocyst complex component Sec10 HD_2 PF12917.7 KFM61544.1 - 0.0003 20.6 0.2 0.0014 18.5 0.1 2.2 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme Occludin_ELL PF07303.13 KFM61544.1 - 0.027 15.2 9.9 4.2 8.2 0.0 4.8 2 1 2 4 4 4 0 Occludin homology domain PMC2NT PF08066.12 KFM61544.1 - 0.12 13.1 0.1 9.6 7.0 0.0 3.1 3 0 0 3 3 3 0 PMC2NT (NUC016) domain ARID PF01388.21 KFM61545.1 - 2.1e-23 82.8 0.5 5.4e-23 81.5 0.5 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.8 KFM61545.1 - 1.3e-11 44.2 3.0 3.9e-11 42.6 3.0 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PIRT PF15099.6 KFM61546.1 - 0.00092 18.8 0.1 0.0012 18.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Sigma_reg_N PF13800.6 KFM61546.1 - 0.0023 18.2 0.5 0.32 11.3 0.0 2.1 1 1 1 2 2 2 1 Sigma factor regulator N-terminal DUF3185 PF11381.8 KFM61546.1 - 0.0042 17.1 3.0 1.1 9.3 1.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3185) Abhydrolase_9_N PF15420.6 KFM61546.1 - 0.0061 16.6 0.0 0.0073 16.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus Saf_2TM PF18303.1 KFM61546.1 - 0.019 14.6 0.3 0.14 11.7 0.3 1.9 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain ATP19 PF11022.8 KFM61546.1 - 0.073 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase subunit K SUR7 PF06687.12 KFM61546.1 - 0.24 11.0 2.3 0.43 10.2 0.5 1.9 1 1 1 2 2 2 0 SUR7/PalI family SdpI PF13630.6 KFM61546.1 - 0.29 11.3 3.1 3 8.1 0.1 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF3040 PF11239.8 KFM61546.1 - 0.67 10.3 8.1 4.5 7.6 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF3098 PF11297.8 KFM61546.1 - 1.1 8.9 6.4 2.1 8.0 4.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3098) TMEM100 PF16311.5 KFM61546.1 - 7 6.2 5.8 50 3.5 5.8 2.0 1 1 0 1 1 1 0 Transmembrane protein 100 I-set PF07679.16 KFM61548.1 - 4.9e-42 141.9 0.0 2.5e-14 53.1 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM61548.1 - 3.8e-38 130.0 0.4 3e-14 53.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM61548.1 - 1e-25 89.7 0.1 1.1e-07 31.9 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM61548.1 - 3.6e-21 75.3 0.9 9.5e-10 38.7 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM61548.1 - 4.8e-18 65.3 4.1 4.2e-05 23.7 0.2 5.9 3 3 0 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM61548.1 - 2e-10 40.0 0.1 0.027 14.1 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin domain Ig_5 PF16681.5 KFM61548.1 - 1.2e-05 25.6 0.0 6.9 7.1 0.0 4.1 4 0 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM61548.1 - 1.8e-05 24.7 0.1 0.013 15.5 0.0 2.9 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM61548.1 - 0.00013 22.1 0.3 0.27 11.5 0.0 3.8 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFM61548.1 - 0.00025 21.2 0.0 0.63 10.3 0.0 3.1 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFM61548.1 - 0.045 13.8 0.0 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFM61548.1 - 0.058 13.4 0.1 0.67 9.9 0.0 2.3 2 1 0 2 2 2 0 CD47 immunoglobulin-like domain zf-C2H2 PF00096.26 KFM61549.1 - 2.9e-17 62.1 23.1 1.3e-06 28.5 0.8 3.6 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM61549.1 - 8.8e-17 60.7 21.3 1.3e-06 28.5 1.3 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM61549.1 - 3.3e-11 43.0 21.0 0.0012 19.5 2.0 3.9 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM61549.1 - 3.4e-11 43.1 18.2 0.00045 20.5 0.9 3.9 4 0 0 4 4 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM61549.1 - 9.4e-09 35.3 9.6 0.0056 16.9 0.5 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM61549.1 - 6.6e-07 29.2 18.1 0.0016 18.4 0.6 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM61549.1 - 5.4e-06 26.2 8.0 0.12 12.3 0.2 3.5 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM61549.1 - 0.00048 19.9 6.9 1.2 9.0 0.1 3.4 1 1 2 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KFM61549.1 - 0.0018 17.9 9.1 0.38 10.4 0.3 3.3 1 1 2 3 3 3 2 MYST family zinc finger domain Baculo_IE-1 PF05290.11 KFM61549.1 - 0.0052 16.7 5.9 2.1 8.3 0.0 3.2 1 1 2 3 3 3 1 Baculovirus immediate-early protein (IE-0) zf-Sec23_Sec24 PF04810.15 KFM61549.1 - 0.011 15.8 6.9 3.3 7.9 0.1 3.7 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM61549.1 - 0.012 15.5 0.2 4.5 7.2 0.0 2.8 1 1 2 3 3 3 0 GAGA factor DUF2256 PF10013.9 KFM61549.1 - 0.027 14.6 8.9 9.7 6.4 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zf_RING PF16744.5 KFM61549.1 - 0.029 14.5 9.5 2.3 8.4 0.4 3.2 1 1 2 3 3 3 0 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KFM61549.1 - 0.03 14.6 16.0 2.7 8.4 1.6 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFM61549.1 - 0.038 14.1 5.4 0.38 10.9 1.6 2.7 1 1 2 3 3 3 0 Zinc ribbon domain zf-BED PF02892.15 KFM61549.1 - 0.066 13.3 2.0 0.066 13.3 2.0 3.4 1 1 2 3 3 3 0 BED zinc finger zf_UBZ PF18439.1 KFM61549.1 - 0.095 12.3 9.4 1.6 8.4 0.3 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM61549.1 - 0.11 12.6 6.4 0.14 12.3 5.7 1.6 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFM61549.1 - 0.16 12.7 9.6 0.72 10.6 3.0 2.3 1 1 0 2 2 2 0 zinc-ribbon family zf-RING_7 PF02591.15 KFM61549.1 - 0.2 11.9 2.2 0.71 10.1 0.0 2.6 3 0 0 3 3 3 0 C4-type zinc ribbon domain VATC PF18716.1 KFM61549.1 - 0.2 11.5 6.4 1.4 8.9 0.1 3.3 3 0 0 3 3 3 0 Vms1-associating treble clef domain zf-DBF PF07535.12 KFM61549.1 - 0.33 11.1 16.1 4.1 7.6 0.3 4.2 3 1 1 4 4 4 0 DBF zinc finger zf-C2H2_8 PF15909.5 KFM61549.1 - 0.34 11.2 8.3 0.63 10.4 7.0 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFM61549.1 - 0.41 10.5 21.2 0.45 10.3 0.9 3.8 4 0 0 4 4 3 0 C2H2-type zinc-finger domain zf-FCS PF06467.14 KFM61549.1 - 0.52 10.3 7.0 4.7 7.2 0.2 3.3 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif RecR PF02132.15 KFM61549.1 - 0.78 9.4 10.1 3.7 7.2 0.4 3.2 2 1 0 2 2 2 0 RecR protein zf-HIT PF04438.16 KFM61549.1 - 1 9.3 8.2 18 5.3 0.3 3.3 3 0 0 3 3 3 0 HIT zinc finger DZR PF12773.7 KFM61549.1 - 1.2 9.2 6.6 8.8 6.4 4.8 2.4 2 1 0 2 2 1 0 Double zinc ribbon FYVE PF01363.21 KFM61549.1 - 1.8 8.7 13.9 6.2 7.0 11.5 3.1 2 1 0 2 2 1 0 FYVE zinc finger Rpr2 PF04032.16 KFM61549.1 - 3.1 8.1 9.4 6.4 7.1 3.2 2.6 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_11 PF16622.5 KFM61549.1 - 6.4 6.6 10.1 5.3 6.9 0.1 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type YjeF_N PF03853.15 KFM61550.1 - 5.2e-16 59.0 0.0 8.3e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus LSM14 PF12701.7 KFM61550.1 - 3e-10 40.1 0.4 7.6e-10 38.8 0.4 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KFM61550.1 - 5.4e-08 33.7 2.1 3.4e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 FDF domain HMMR_C PF15908.5 KFM61550.1 - 0.0039 17.5 0.4 0.0067 16.7 0.4 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal DUF4166 PF13761.6 KFM61550.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) Ccdc124 PF06244.12 KFM61551.1 - 1.2e-34 119.6 33.5 6.9e-32 110.7 33.5 2.8 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KFM61551.1 - 0.00037 20.8 0.5 0.00037 20.8 0.5 3.2 3 0 0 3 3 3 1 HMG (high mobility group) box DUF563 PF04577.14 KFM61552.1 - 1.2e-09 38.7 0.0 1.7e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) GLTP PF08718.11 KFM61554.1 - 3.8e-41 140.8 0.1 4.6e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) RRM_1 PF00076.22 KFM61555.1 - 1.3e-42 143.5 0.0 3.5e-24 84.4 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KFM61555.1 - 1.9e-25 89.8 0.0 4.5e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KFM61555.1 - 9.4e-07 28.6 0.0 0.012 15.4 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KFM61555.1 - 1.8e-05 24.3 0.0 0.033 13.8 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM61555.1 - 0.012 15.6 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Orf78 PF06024.12 KFM61555.1 - 0.55 10.6 2.5 0.57 10.5 0.0 2.2 2 1 0 2 2 2 0 Orf78 (ac78) DEAD PF00270.29 KFM61556.1 - 2.6e-42 144.6 0.0 3.2e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SPRY PF00622.28 KFM61556.1 - 8.5e-23 80.7 0.1 1.7e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 SPRY domain CMS1 PF14617.6 KFM61556.1 - 0.095 12.0 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFM61556.1 - 0.12 12.3 0.0 9 6.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFM61557.1 - 2.1e-26 92.4 0.0 3.6e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ANF_receptor PF01094.28 KFM61558.1 - 0.0071 15.5 0.1 0.0073 15.4 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 KFM61559.1 - 3.5e-19 69.1 0.0 3.8e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region DUF1846 PF08903.11 KFM61559.1 - 0.088 11.3 0.3 0.11 11.0 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Peripla_BP_6 PF13458.6 KFM61559.1 - 0.25 11.0 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Ig_3 PF13927.6 KFM61560.1 - 5.1e-48 161.6 0.3 7.8e-10 39.2 0.1 5.7 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFM61560.1 - 8.1e-43 144.4 0.1 1.6e-08 34.5 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM61560.1 - 1.6e-30 105.2 0.2 2.2e-07 31.1 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFM61560.1 - 3.3e-25 88.1 0.0 8.2e-06 25.9 0.0 6.0 6 0 0 6 6 6 4 Immunoglobulin domain fn3 PF00041.21 KFM61560.1 - 2e-22 79.3 2.4 3.6e-13 49.7 0.0 3.7 4 0 0 4 4 4 2 Fibronectin type III domain V-set PF07686.17 KFM61560.1 - 7.2e-17 61.5 0.3 0.00026 21.1 0.0 6.1 5 1 0 5 5 5 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM61560.1 - 3e-08 33.1 0.0 0.6 9.7 0.0 5.0 5 0 0 5 5 5 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM61560.1 - 1.7e-05 25.3 0.0 0.19 12.3 0.0 3.4 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFM61560.1 - 7.3e-05 22.8 0.2 3.8 7.6 0.0 4.0 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM61560.1 - 0.00068 19.6 0.0 1.9 8.6 0.0 4.5 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 KFM61560.1 - 0.002 16.9 0.1 0.13 11.0 0.0 3.2 1 1 2 4 4 4 1 Alphaherpesvirus glycoprotein E C1-set PF07654.15 KFM61560.1 - 0.0078 16.6 0.1 5.3 7.5 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin C1-set domain C2-set PF05790.15 KFM61560.1 - 0.014 15.5 0.1 0.35 11.1 0.0 3.3 4 0 0 4 4 4 0 Immunoglobulin C2-set domain DUF2808 PF10989.8 KFM61560.1 - 0.026 14.5 0.5 7.3 6.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2808) Arylsulfotran_N PF17425.2 KFM61560.1 - 0.06 13.4 0.0 0.45 10.6 0.0 2.5 2 0 0 2 2 2 0 Arylsulfotransferase Ig-like domain zf-RING_2 PF13639.6 KFM61562.1 - 1.9e-07 31.3 15.9 1.9e-07 31.3 15.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM61562.1 - 2.2e-06 27.4 17.1 8.9e-06 25.5 17.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM61562.1 - 5.5e-06 26.6 11.1 1.5e-05 25.2 11.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM61562.1 - 3.1e-05 23.7 16.5 8.2e-05 22.4 16.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM61562.1 - 3.6e-05 23.5 13.6 0.0001 22.1 13.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM61562.1 - 5.2e-05 23.1 14.7 0.00014 21.7 14.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFM61562.1 - 0.0002 21.0 10.1 0.00074 19.2 10.1 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFM61562.1 - 0.002 18.1 12.7 0.0051 16.8 12.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM61562.1 - 0.052 13.4 13.5 0.12 12.2 13.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFM61562.1 - 0.14 12.2 9.3 0.6 10.2 9.3 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-ZPR1 PF03367.13 KFM61563.1 - 2.1e-40 138.2 0.0 2.6e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain zf-ZPR1 PF03367.13 KFM61564.1 - 5.8e-52 175.7 6.0 4.8e-51 172.8 0.4 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain ZapB PF06005.12 KFM61564.1 - 0.0097 16.3 0.5 0.077 13.4 0.0 2.2 2 0 0 2 2 2 1 Cell division protein ZapB DUF2024 PF09630.10 KFM61564.1 - 0.12 12.2 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) CtIP_N PF10482.9 KFM61564.1 - 0.31 11.1 3.4 0.37 10.9 0.0 2.4 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Porin_3 PF01459.22 KFM61565.1 - 6.1e-65 219.4 0.0 7e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF1307 PF06998.11 KFM61565.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) UCH PF00443.29 KFM61566.1 - 9.6e-50 169.5 0.9 1.9e-49 168.5 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM61566.1 - 5.1e-06 26.3 0.4 0.00041 20.1 0.4 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 KFM61566.1 - 2.5e-05 23.9 3.6 0.0077 16.1 0.2 3.2 2 0 0 2 2 2 2 Ubiquitin interaction motif CLZ PF16526.5 KFM61566.1 - 0.044 14.1 0.6 7.5 7.0 0.2 3.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2247 PF10004.9 KFM61566.1 - 0.076 12.8 2.2 0.48 10.2 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF5082 PF16888.5 KFM61566.1 - 0.1 12.9 4.2 3.3 8.0 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KFM61566.1 - 0.1 12.6 1.7 10 6.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 KFM61566.1 - 0.2 11.1 4.3 1.1 8.6 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) RasGAP_C PF03836.15 KFM61566.1 - 0.76 9.9 4.3 0.8 9.8 1.1 2.6 2 0 0 2 2 2 0 RasGAP C-terminus DUF4200 PF13863.6 KFM61566.1 - 9.6 6.6 14.4 1.3 9.4 1.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF4819 PF16090.5 KFM61567.1 - 8.8e-25 86.6 0.1 2.4e-24 85.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4819) HMG_box PF00505.19 KFM61567.1 - 2.3e-16 60.0 3.5 4.4e-16 59.0 3.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM61567.1 - 1.1e-06 29.1 1.4 2.8e-06 27.8 1.4 1.7 1 0 0 1 1 1 1 HMG-box domain DUF4537 PF15057.6 KFM61567.1 - 0.11 12.5 0.0 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) DUF3035 PF11233.8 KFM61567.1 - 0.3 11.4 6.7 5.1 7.4 2.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Dimer_Tnp_hAT PF05699.14 KFM61568.1 - 0.0013 18.5 0.4 0.0025 17.6 0.4 1.6 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region UPF0029 PF01205.19 KFM61569.1 - 4.1e-35 120.3 0.1 6.9e-35 119.6 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KFM61569.1 - 3.3e-15 56.4 1.8 5.6e-15 55.7 1.2 1.7 2 0 0 2 2 2 1 RWD domain CTD_bind PF04818.13 KFM61570.1 - 1.8e-17 63.9 0.2 5.6e-17 62.3 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KFM61570.1 - 4.7e-09 36.0 0.0 9e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ets PF00178.22 KFM61571.1 - 1.6e-11 44.5 2.1 2.3e-11 44.0 2.1 1.2 1 0 0 1 1 1 1 Ets-domain VPS13_C PF16909.5 KFM61572.1 - 1.4e-65 220.4 4.9 4.4e-62 209.0 0.2 2.3 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 KFM61572.1 - 1.1e-07 32.1 0.0 8.8e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain bPH_3 PF14470.6 KFM61572.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.9 1 0 0 1 1 1 0 Bacterial PH domain SHR-BD PF06650.12 KFM61573.1 - 2.7e-30 105.7 0.0 5.4e-30 104.7 0.0 1.5 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 DUF2750 PF11042.8 KFM61573.1 - 0.0022 18.0 0.0 0.0054 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2750) VPS13_mid_rpt PF16910.5 KFM61574.1 - 7.1e-14 51.8 9.1 3.6e-12 46.2 3.7 3.9 2 2 0 2 2 2 2 Repeating coiled region of VPS13 VPS13 PF16908.5 KFM61574.1 - 0.00025 20.9 0.2 0.0036 17.1 0.0 2.9 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal DDE_Tnp_1_7 PF13843.6 KFM61575.1 - 7.7e-29 101.1 1.4 9.6e-29 100.8 1.4 1.1 1 0 0 1 1 1 1 Transposase IS4 DUF1265 PF06887.14 KFM61576.1 - 0.25 11.4 3.6 0.55 10.2 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1265) Kinesin PF00225.23 KFM61581.1 - 3.6e-07 29.4 0.0 4.7e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM61581.1 - 0.00046 20.1 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding PAP2 PF01569.21 KFM61582.1 - 4.3e-18 65.4 3.4 4.3e-18 65.4 3.4 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFM61582.1 - 9.6e-10 38.5 6.3 3e-09 36.8 6.3 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFM61582.1 - 6e-06 26.7 3.4 6e-06 26.7 3.4 2.2 2 0 0 2 2 2 1 PAP2 superfamily C-terminal INSIG PF07281.12 KFM61582.1 - 0.048 13.3 0.4 0.069 12.8 0.4 1.2 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) DUF3808 PF10300.9 KFM61583.1 - 7.7e-124 414.0 2.2 1.2e-123 413.4 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_1 PF00515.28 KFM61583.1 - 1.1e-07 31.3 0.1 0.029 14.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM61583.1 - 1.9e-06 28.1 0.8 0.21 11.9 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM61583.1 - 2.5e-06 27.2 0.0 0.34 11.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM61583.1 - 6.2e-05 22.8 0.1 4.4 7.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM61583.1 - 0.0011 18.5 0.1 4.4 6.6 0.0 3.1 3 0 0 3 3 3 1 MalT-like TPR region TPR_11 PF13414.6 KFM61583.1 - 0.0065 16.1 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 KFM61583.1 - 0.0076 17.0 0.0 83 4.4 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM61583.1 - 0.014 16.0 1.3 37 5.3 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM61583.1 - 0.036 14.6 0.6 3 8.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KFM61583.1 - 0.068 13.2 0.3 8.2 6.6 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 KFM61583.1 - 0.12 12.4 0.8 18 5.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat HSP70 PF00012.20 KFM61584.1 - 1.2e-78 264.8 0.8 1.3e-78 264.7 0.8 1.0 1 0 0 1 1 1 1 Hsp70 protein Radial_spoke_3 PF06098.11 KFM61584.1 - 0.012 14.9 1.7 0.018 14.3 1.7 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 Ribosomal_L29 PF00831.23 KFM61584.1 - 0.54 10.3 3.0 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein HSP70 PF00012.20 KFM61585.1 - 2.5e-148 495.0 0.1 2.8e-148 494.8 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM61585.1 - 7.2e-13 48.0 0.0 2.4e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 KFM61585.1 - 0.0044 16.3 0.6 0.011 15.0 0.1 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase StbA PF06406.11 KFM61585.1 - 0.023 14.0 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 StbA protein FtsA PF14450.6 KFM61585.1 - 0.32 11.4 2.1 1.4 9.4 0.2 2.6 2 2 0 2 2 2 0 Cell division protein FtsA IGFBP PF00219.18 KFM61586.1 - 3.4e-09 37.2 20.2 3.4e-09 37.2 20.2 2.9 2 1 0 2 2 2 1 Insulin-like growth factor binding protein Pkinase_Tyr PF07714.17 KFM61587.1 - 3.4e-58 197.0 0.0 5.2e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM61587.1 - 1.5e-27 96.6 0.0 2.3e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFM61587.1 - 1.1e-08 35.2 3.1 2e-08 34.4 1.8 2.0 2 0 0 2 2 2 1 Fibronectin type III domain PTP_tm PF18861.1 KFM61587.1 - 0.00024 21.1 0.5 0.0023 18.0 0.5 2.2 1 1 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2207 PF09972.9 KFM61587.1 - 0.0022 16.8 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Orf78 PF06024.12 KFM61587.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) zf-C3HC4_2 PF13923.6 KFM61590.1 - 9.9e-14 50.9 10.8 1.3e-13 50.5 10.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM61590.1 - 9e-10 38.3 12.9 1.3e-09 37.8 12.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM61590.1 - 1.2e-09 37.9 7.5 1.5e-09 37.5 7.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM61590.1 - 2.1e-08 34.1 11.3 3.6e-08 33.3 11.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM61590.1 - 2.2e-08 33.9 11.4 3.3e-08 33.4 11.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFM61590.1 - 3.2e-08 33.8 10.5 4.5e-08 33.3 10.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFM61590.1 - 1.5e-05 25.0 11.3 2.6e-05 24.3 11.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFM61590.1 - 0.0001 22.1 9.8 0.0022 17.8 10.0 2.1 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFM61590.1 - 0.0011 19.2 11.4 0.006 16.9 11.4 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFM61590.1 - 0.0019 18.3 4.2 0.0028 17.8 4.2 1.2 1 0 0 1 1 1 1 zinc RING finger of MSL2 Rtf2 PF04641.12 KFM61590.1 - 0.012 15.0 1.3 0.013 14.9 1.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_4 PF14570.6 KFM61590.1 - 0.029 14.2 10.8 0.36 10.6 11.7 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KFM61590.1 - 0.054 13.3 7.1 0.082 12.7 7.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 KFM61590.1 - 0.095 12.5 7.9 0.28 11.0 7.9 1.8 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 KFM61590.1 - 0.11 12.4 3.9 0.15 11.9 3.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 KFM61590.1 - 0.62 10.2 8.6 1.2 9.2 8.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zinc_ribbon_9 PF14369.6 KFM61590.1 - 0.75 10.1 7.2 21 5.5 0.0 2.6 2 1 0 2 2 2 0 zinc-ribbon zf_C2H2_10 PF18414.1 KFM61590.1 - 1 8.9 8.9 1.8 8.2 0.1 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger HSP70 PF00012.20 KFM61591.1 - 1e-267 889.2 12.8 1.1e-267 889.1 12.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM61591.1 - 4e-18 65.3 1.2 1.4e-16 60.2 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFM61591.1 - 1.9e-05 25.0 4.9 0.07 13.6 0.1 3.8 3 2 0 3 3 3 2 Cell division protein FtsA DUF4624 PF15417.6 KFM61591.1 - 0.00043 20.1 0.1 0.2 11.5 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4624) Hydantoinase_A PF01968.18 KFM61591.1 - 0.0013 18.1 0.6 0.014 14.6 0.1 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 KFM61591.1 - 0.0097 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KFM61591.1 - 0.014 14.4 0.5 0.075 12.0 0.5 2.0 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain EutA PF06277.11 KFM61591.1 - 0.13 11.1 3.4 5.2 5.8 0.2 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutA MutS_III PF05192.18 KFM61591.1 - 0.38 10.9 3.6 3.5 7.8 2.0 2.3 2 0 0 2 2 2 0 MutS domain III DUF4795 PF16043.5 KFM61591.1 - 1.2 8.7 13.7 0.06 13.0 5.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF16 PF01519.16 KFM61591.1 - 1.3 9.5 13.1 0.77 10.3 4.7 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 OmpH PF03938.14 KFM61591.1 - 9.5 6.6 18.4 6.7 7.0 10.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Methyltransf_PK PF05891.12 KFM61592.1 - 7.5e-30 104.1 0.0 8.3e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.14 KFM61592.1 - 0.0071 15.9 0.0 0.0081 15.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFM61592.1 - 0.048 14.4 0.0 0.071 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFM61592.1 - 0.093 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain eIF3g PF12353.8 KFM61593.1 - 2.3e-06 28.0 0.2 3.8e-06 27.3 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G ABC_tran PF00005.27 KFM61594.1 - 1.2e-39 136.0 0.1 2e-27 96.3 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 KFM61594.1 - 8.2e-37 127.3 9.2 1.3e-36 126.7 9.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KFM61594.1 - 1.6e-13 50.6 1.9 8.7e-06 25.3 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM61594.1 - 0.0097 15.7 1.6 2.7 7.7 0.6 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KFM61594.1 - 0.029 14.6 0.0 11 6.3 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KFM61594.1 - 0.051 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KFM61594.1 - 0.067 13.3 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KFM61594.1 - 0.09 12.9 1.1 0.41 10.7 0.4 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF808 PF05661.12 KFM61594.1 - 0.096 11.7 0.3 0.19 10.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF808) IstB_IS21 PF01695.17 KFM61594.1 - 0.14 11.9 0.8 2.9 7.6 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein SDF PF00375.18 KFM61594.1 - 0.18 10.8 4.8 0.31 10.0 4.8 1.3 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family AAA_24 PF13479.6 KFM61594.1 - 0.19 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 KFM61596.1 - 1.3e-12 47.9 10.0 1.5e-12 47.8 10.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region RseC_MucC PF04246.12 KFM61596.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF3853 PF12964.7 KFM61597.1 - 0.16 12.1 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Guanylate_kin PF00625.21 KFM61598.1 - 2.8e-09 36.9 0.0 3.6e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 Guanylate kinase Cep57_CLD_2 PF14197.6 KFM61602.1 - 9.2e-05 22.5 6.6 9.2e-05 22.5 6.6 7.5 5 1 1 6 6 6 3 Centrosome localisation domain of PPC89 Spc7 PF08317.11 KFM61602.1 - 0.0011 17.9 10.1 0.0011 17.9 10.1 4.9 2 2 2 4 4 3 2 Spc7 kinetochore protein DUF5344 PF17279.2 KFM61602.1 - 0.0018 18.8 0.7 0.0018 18.8 0.7 5.5 4 1 1 6 6 6 1 Family of unknown function (DUF5344) BRE1 PF08647.11 KFM61602.1 - 0.0026 17.8 15.8 0.0026 17.8 15.8 5.8 3 2 1 5 5 5 2 BRE1 E3 ubiquitin ligase WEMBL PF05701.11 KFM61602.1 - 0.004 15.9 2.4 0.004 15.9 2.4 5.1 2 2 2 5 5 5 3 Weak chloroplast movement under blue light ERM PF00769.19 KFM61602.1 - 0.004 17.0 12.5 0.004 17.0 12.5 4.3 2 1 2 4 4 4 2 Ezrin/radixin/moesin family APG6_N PF17675.1 KFM61602.1 - 0.0054 17.3 84.7 0.7 10.4 10.0 6.1 1 1 3 5 5 5 3 Apg6 coiled-coil region FIVAR PF07554.13 KFM61602.1 - 0.017 15.9 0.1 0.017 15.9 0.1 2.8 2 0 0 2 2 2 0 FIVAR domain HALZ PF02183.18 KFM61602.1 - 0.039 14.2 1.0 0.039 14.2 1.0 8.4 7 1 1 8 8 8 0 Homeobox associated leucine zipper CotJB PF12652.7 KFM61602.1 - 0.071 13.3 0.3 0.071 13.3 0.3 5.1 5 1 1 6 6 6 0 CotJB protein ATG16 PF08614.11 KFM61602.1 - 0.086 13.1 58.6 0.54 10.5 13.0 3.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) TSC22 PF01166.18 KFM61602.1 - 0.21 11.9 0.2 0.21 11.9 0.2 7.3 7 2 2 9 9 9 0 TSC-22/dip/bun family Sec8_exocyst PF04048.14 KFM61602.1 - 0.31 10.9 25.4 2.3 8.1 1.0 6.2 3 1 3 6 6 6 0 Sec8 exocyst complex component specific domain HOOK PF05622.12 KFM61602.1 - 0.61 8.2 59.1 0.58 8.2 37.3 2.3 2 0 0 2 2 2 0 HOOK protein DASH_Dad1 PF08649.10 KFM61602.1 - 0.64 10.3 3.3 3.6 7.8 0.2 3.8 3 1 0 3 3 3 0 DASH complex subunit Dad1 TMF_TATA_bd PF12325.8 KFM61602.1 - 1.3 9.3 68.2 3 8.1 3.5 7.4 2 2 5 7 7 7 0 TATA element modulatory factor 1 TATA binding Taxilin PF09728.9 KFM61602.1 - 1.8 7.7 64.7 0.12 11.6 1.0 4.2 3 1 1 4 4 4 0 Myosin-like coiled-coil protein DUF948 PF06103.11 KFM61602.1 - 3 8.1 21.9 32 4.9 0.6 6.3 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF4686 PF15742.5 KFM61602.1 - 5 6.2 60.9 0.15 11.2 35.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) ApoO PF09769.9 KFM61602.1 - 6.5 6.7 8.5 5.3 7.0 0.5 3.8 2 2 1 3 3 3 0 Apolipoprotein O CARD PF00619.21 KFM61603.1 - 9e-16 57.7 0.1 1.2e-15 57.3 0.1 1.2 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 KFM61603.1 - 1.7e-07 31.1 0.2 3e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Caspase recruitment domain DUF1759 PF03564.15 KFM61604.1 - 0.00025 21.0 1.0 0.00051 20.0 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1759) DUF4246 PF14033.6 KFM61604.1 - 0.037 13.1 0.1 0.055 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Com_YlbF PF06133.11 KFM61604.1 - 0.17 12.5 1.2 8.6 7.0 0.2 2.6 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DUF4200 PF13863.6 KFM61604.1 - 1.5 9.3 5.3 15 6.0 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) PINIT PF14324.6 KFM61605.1 - 2.7e-31 108.9 1.1 5.3e-31 107.9 0.7 1.7 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.20 KFM61605.1 - 1.6e-20 72.6 4.3 3.4e-20 71.5 4.3 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFM61605.1 - 0.00065 19.5 0.9 0.0019 18.0 0.9 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KFM61605.1 - 0.28 11.1 2.8 0.64 10.0 2.8 1.6 1 0 0 1 1 1 0 PHD-finger DUF4817 PF16087.5 KFM61606.1 - 4.5e-10 39.2 0.0 5.7e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) Acyl_transf_3 PF01757.22 KFM61607.1 - 8.7e-09 34.9 38.9 1.4e-08 34.2 38.9 1.3 1 0 0 1 1 1 1 Acyltransferase family ETRAMP PF09716.10 KFM61607.1 - 0.11 12.5 1.5 3.2 7.9 0.0 3.5 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) UL42 PF17638.2 KFM61607.1 - 0.2 11.6 0.8 2 8.4 0.2 2.7 2 0 0 2 2 2 0 HCMV UL42 DUF4371 PF14291.6 KFM61608.1 - 4.6e-10 39.5 0.1 2e-09 37.5 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM61608.1 - 0.0028 17.2 0.4 0.0028 17.2 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger C2H2-type Acyl_transf_3 PF01757.22 KFM61610.1 - 2.3e-11 43.4 33.3 3e-11 43.0 33.3 1.0 1 0 0 1 1 1 1 Acyltransferase family Spc110_C PF18520.1 KFM61610.1 - 0.12 12.0 1.1 1.2 8.8 0.1 2.6 2 1 1 3 3 3 0 Spindle pole body component 110 C-terminal domain DUF962 PF06127.11 KFM61610.1 - 3.7 7.7 11.7 0.16 12.1 3.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF962) AMH_N PF04709.12 KFM61611.1 - 0.058 12.3 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region CLP1_P PF16575.5 KFM61612.1 - 5.9e-05 22.9 0.0 6.5e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KFM61613.1 - 1.3e-10 41.3 0.0 1.6e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KFM61613.1 - 4.6e-08 33.1 0.0 7.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 KFM61613.1 - 0.0086 16.2 0.0 0.016 15.3 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM61613.1 - 0.01 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KFM61613.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KFM61613.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFM61613.1 - 0.093 13.0 0.0 0.23 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain RVT_2 PF07727.14 KFM61614.1 - 3.4e-42 144.8 0.1 4.5e-42 144.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MULE PF10551.9 KFM61615.1 - 5.2e-14 52.4 1.8 1.3e-13 51.1 0.4 2.5 3 0 0 3 3 3 1 MULE transposase domain zf-C2H2 PF00096.26 KFM61615.1 - 3.1e-06 27.3 23.9 5.6e-05 23.4 0.4 4.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61615.1 - 1.5e-05 25.4 24.7 0.0084 16.9 0.4 5.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM61615.1 - 0.00026 21.2 7.5 0.099 13.1 0.5 4.5 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFM61615.1 - 0.0005 20.0 5.2 0.14 12.2 0.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM61615.1 - 0.0034 17.6 0.3 0.0034 17.6 0.3 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding UPF0184 PF03670.13 KFM61615.1 - 0.042 14.2 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) zf_C2H2_ZHX PF18387.1 KFM61615.1 - 0.045 13.4 0.4 0.045 13.4 0.4 4.6 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain rve_3 PF13683.6 KFM61615.1 - 0.072 12.9 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain DDE_1 PF03184.19 KFM61616.1 - 5.8e-50 169.4 0.1 1e-49 168.6 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM61616.1 - 7.9e-12 45.0 2.4 2e-11 43.8 0.0 2.8 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM61616.1 - 0.0012 18.4 0.0 0.0037 16.9 0.0 1.9 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Fumerase PF05681.14 KFM61619.1 - 0.055 12.9 0.1 0.055 12.9 0.1 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) TBCA PF02970.16 KFM61620.1 - 4.1e-28 97.5 8.4 4.8e-28 97.3 8.4 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A RE_ApaLI PF09499.10 KFM61620.1 - 0.012 15.3 0.6 0.014 15.1 0.6 1.0 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease DBINO PF13892.6 KFM61620.1 - 0.022 15.1 5.7 0.034 14.5 5.7 1.2 1 0 0 1 1 1 0 DNA-binding domain DUF4355 PF14265.6 KFM61620.1 - 0.027 14.7 8.1 0.027 14.7 8.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) AAA_11 PF13086.6 KFM61621.1 - 2.9e-06 27.3 0.0 2.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain OAF PF14941.6 KFM61621.1 - 0.065 12.7 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator, Out at first AAA_12 PF13087.6 KFM61622.1 - 9e-09 35.2 0.0 1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF2208 PF09973.9 KFM61624.1 - 2.7 7.5 5.1 1.3 8.6 1.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) MGC-24 PF05283.11 KFM61625.1 - 0.17 12.3 1.6 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4505 PF14956.6 KFM61627.1 - 2e-85 285.0 1.6 2.5e-85 284.7 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) Malic_M PF03949.15 KFM61627.1 - 0.27 10.5 0.0 0.41 9.9 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain MDD_C PF18376.1 KFM61632.1 - 1.2e-75 253.4 0.0 1.7e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KFM61632.1 - 7.8e-09 35.7 1.6 1.8e-08 34.5 1.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Preseq_ALAS PF09029.10 KFM61633.1 - 0.029 14.8 0.0 0.031 14.8 0.0 1.0 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence DUF4056 PF13265.6 KFM61633.1 - 0.047 13.0 0.0 0.052 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) AAA_lid_3 PF17862.1 KFM61633.1 - 0.081 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA+ lid domain Pkinase PF00069.25 KFM61636.1 - 1.4e-21 77.0 0.0 2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM61636.1 - 1.8e-19 70.1 0.0 2.4e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM61636.1 - 0.0039 16.0 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM61636.1 - 0.021 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFM61636.1 - 0.081 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FAM167 PF11652.8 KFM61638.1 - 0.041 14.4 0.3 0.1 13.1 0.3 1.7 1 1 0 1 1 1 0 FAM167 LRR_8 PF13855.6 KFM61640.1 - 2.6e-08 33.5 1.7 0.0003 20.5 0.7 2.7 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM61640.1 - 5.1e-08 33.1 6.6 0.0051 17.2 0.0 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM61640.1 - 6.5e-06 25.8 2.1 0.61 10.3 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KFM61640.1 - 0.067 13.8 3.3 66 4.6 0.1 4.2 3 1 1 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 KFM61640.1 - 0.26 10.8 4.0 2.3 7.7 0.4 2.7 1 1 2 3 3 3 0 Leucine-rich repeat NAGPA PF09992.9 KFM61642.1 - 7.5e-38 130.4 0.1 1e-37 129.9 0.1 1.2 1 0 0 1 1 1 1 Phosphodiester glycosidase EGF_2 PF07974.13 KFM61642.1 - 0.00054 20.3 30.9 0.0018 18.6 7.7 7.8 7 0 0 7 7 7 4 EGF-like domain DUF1011 PF06237.12 KFM61643.1 - 7.8e-34 116.0 9.9 7.8e-34 116.0 9.9 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1011) GCN5L1 PF06320.13 KFM61645.1 - 0.22 11.7 4.5 0.82 9.8 4.5 2.0 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) bZIP_1 PF00170.21 KFM61645.1 - 0.37 10.9 6.4 0.2 11.8 3.2 2.4 1 1 0 1 1 1 0 bZIP transcription factor MCM6_C PF18263.1 KFM61645.1 - 9.3 6.5 9.7 46 4.3 9.7 2.2 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Herpes_UL92 PF03048.14 KFM61646.1 - 1.8 8.3 4.9 10 5.8 0.9 2.9 2 1 1 3 3 3 0 UL92 family DDE_3 PF13358.6 KFM61647.1 - 3.9e-13 49.4 0.7 2.6e-12 46.7 0.2 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease DUF560 PF04575.13 KFM61647.1 - 0.0048 16.4 0.0 0.0089 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF560) DUF1456 PF07308.13 KFM61647.1 - 0.13 12.6 0.0 0.59 10.5 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) Apolipoprotein PF01442.18 KFM61648.1 - 2.7e-15 56.8 68.0 1.4e-09 38.1 28.4 2.9 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM61648.1 - 4.3e-08 33.3 6.3 0.00012 22.2 3.0 3.9 2 1 2 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF842 PF05811.13 KFM61648.1 - 7.4e-07 28.9 30.2 0.027 14.2 2.9 3.7 1 1 3 4 4 4 4 Eukaryotic protein of unknown function (DUF842) Prominin PF05478.11 KFM61648.1 - 0.00055 18.1 18.2 0.00055 18.1 18.2 2.2 1 1 1 2 2 2 2 Prominin DUF1664 PF07889.12 KFM61648.1 - 0.0025 17.8 38.5 0.0042 17.1 3.9 3.8 2 1 2 4 4 4 2 Protein of unknown function (DUF1664) DUF1451 PF07295.11 KFM61648.1 - 0.0031 17.6 15.8 0.0031 17.6 15.8 3.2 1 1 2 3 3 3 1 Zinc-ribbon containing domain DUF1640 PF07798.11 KFM61648.1 - 0.0032 17.6 39.5 0.06 13.4 25.1 3.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1640) CdvA PF18822.1 KFM61648.1 - 0.0065 16.3 41.3 0.4 10.5 0.4 4.5 1 1 3 4 4 4 2 CdvA-like coiled-coil domain AIP3 PF03915.13 KFM61648.1 - 0.01 14.9 37.2 0.12 11.5 34.4 2.2 1 1 1 2 2 2 0 Actin interacting protein 3 Strep_SA_rep PF06696.11 KFM61648.1 - 0.017 15.1 21.9 1.8 8.6 0.3 7.1 4 1 4 8 8 5 0 Streptococcal surface antigen repeat DUF883 PF05957.13 KFM61648.1 - 0.061 13.9 36.8 0.19 12.3 11.7 4.3 2 1 3 5 5 4 0 Bacterial protein of unknown function (DUF883) FlaC_arch PF05377.11 KFM61648.1 - 0.078 13.4 1.2 0.078 13.4 1.2 6.9 1 1 2 3 3 2 0 Flagella accessory protein C (FlaC) YtxH PF12732.7 KFM61648.1 - 0.082 13.4 45.7 4.4 7.9 9.7 4.6 1 1 2 3 3 3 0 YtxH-like protein NPV_P10 PF05531.12 KFM61648.1 - 0.094 13.2 23.1 7.3 7.1 2.7 5.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Mitofilin PF09731.9 KFM61648.1 - 0.1 11.5 41.9 0.16 10.8 41.9 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ApoO PF09769.9 KFM61648.1 - 0.1 12.6 16.4 8.4 6.4 0.5 4.1 1 1 1 2 2 2 0 Apolipoprotein O ApoLp-III PF07464.11 KFM61648.1 - 0.12 12.5 45.1 0.11 12.6 31.9 2.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CwsA PF10814.8 KFM61648.1 - 0.16 12.2 24.6 3.8 7.7 3.0 4.9 3 1 2 5 5 5 0 Cell wall synthesis protein CwsA PIN_8 PF18476.1 KFM61648.1 - 0.24 11.2 31.2 2.4 7.9 14.6 2.4 1 1 1 2 2 2 0 PIN like domain SF-assemblin PF06705.11 KFM61648.1 - 0.25 10.6 38.2 0.22 10.8 30.1 2.6 1 1 1 2 2 2 0 SF-assemblin/beta giardin Prefoldin_2 PF01920.20 KFM61648.1 - 0.32 11.0 0.2 0.32 11.0 0.2 5.7 1 1 3 5 5 5 0 Prefoldin subunit DUF4510 PF14971.6 KFM61648.1 - 0.33 11.3 22.5 30 4.9 0.3 4.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4510) dCache_2 PF08269.11 KFM61648.1 - 0.56 9.3 35.8 1.6 7.8 5.3 3.3 1 1 2 3 3 3 0 Cache domain Cache_3-Cache_2 PF17201.4 KFM61648.1 - 0.89 8.8 22.1 0.41 9.9 6.1 3.2 1 1 2 3 3 3 0 Cache 3/Cache 2 fusion domain Focal_AT PF03623.13 KFM61648.1 - 1.1 9.2 27.6 0.36 10.8 7.6 3.4 1 1 2 3 3 3 0 Focal adhesion targeting region Syntaxin PF00804.25 KFM61648.1 - 1.3 8.7 39.1 17 5.0 22.4 3.7 1 1 1 2 2 2 0 Syntaxin Phasin PF05597.11 KFM61648.1 - 1.3 9.0 45.9 0.083 12.9 5.3 4.7 2 1 1 3 3 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tweety PF04906.13 KFM61648.1 - 2 7.0 18.3 0.07 11.8 0.5 2.9 1 1 2 3 3 3 0 Tweety Baculo_p24 PF05073.12 KFM61648.1 - 2.3 8.0 20.5 7.9 6.2 9.6 2.8 1 1 1 2 2 2 0 Baculovirus P24 capsid protein MtrG PF04210.13 KFM61648.1 - 3 7.8 9.3 11 6.0 0.3 3.9 2 1 2 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Spore_III_AB PF09548.10 KFM61648.1 - 3.4 7.7 22.4 17 5.4 0.3 3.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Serine_rich PF08824.10 KFM61648.1 - 4 7.4 15.5 2.7 8.0 4.9 2.9 1 1 2 3 3 3 0 Serine rich protein interaction domain Grg1 PF11034.8 KFM61648.1 - 4.1 7.7 34.8 15 5.9 10.5 4.5 1 1 4 5 5 4 0 Glucose-repressible protein Grg1 Exonuc_VII_L PF02601.15 KFM61648.1 - 5 6.6 28.2 0.63 9.5 10.7 2.4 1 1 1 2 2 2 0 Exonuclease VII, large subunit TMEM192 PF14802.6 KFM61649.1 - 0.023 13.8 0.0 0.024 13.7 0.0 1.0 1 0 0 1 1 1 0 TMEM192 family DUF1758 PF05585.12 KFM61650.1 - 0.0016 18.2 0.1 0.0025 17.6 0.1 1.2 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Peptidase_A17 PF05380.13 KFM61651.1 - 1.2e-05 25.4 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase VTC PF09359.10 KFM61651.1 - 0.17 11.3 1.4 0.25 10.7 1.4 1.3 1 0 0 1 1 1 0 VTC domain Guanylate_kin PF00625.21 KFM61654.1 - 1.7e-42 145.2 0.0 9.2e-42 142.8 0.0 1.9 1 1 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.28 KFM61654.1 - 6.5e-08 32.1 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM61654.1 - 4.2e-06 26.4 0.1 1.2e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFM61654.1 - 0.037 13.9 0.1 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain L27 PF02828.16 KFM61655.1 - 4.8e-12 45.4 8.0 1.4e-06 27.9 0.6 2.4 2 0 0 2 2 2 2 L27 domain PDZ PF00595.24 KFM61655.1 - 1.8e-09 37.8 0.9 4e-09 36.7 0.9 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM61655.1 - 2.1e-08 33.8 3.2 2.2e-06 27.4 0.3 3.5 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFM61655.1 - 0.039 14.3 0.9 0.039 14.3 0.9 2.3 3 1 0 3 3 3 0 PDZ domain Filamin PF00630.19 KFM61656.1 - 1.7e-08 35.2 0.7 1.7e-08 35.2 0.7 2.6 2 1 0 2 2 2 1 Filamin/ABP280 repeat Tubulin PF00091.25 KFM61657.1 - 1.2e-67 227.9 0.0 1.6e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM61657.1 - 2.6e-52 176.3 0.0 4.1e-52 175.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFM61657.1 - 0.00095 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Rad17 PF03215.15 KFM61658.1 - 2.3e-08 34.2 0.1 6.6e-08 32.7 0.1 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KFM61658.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA C-terminal domain DUF3519 PF12033.8 KFM61658.1 - 0.015 15.7 0.1 0.046 14.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) TraB PF01963.17 KFM61661.1 - 2.7e-31 109.5 0.0 4.2e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 TraB family PspB PF06667.12 KFM61662.1 - 0.18 11.9 3.1 0.18 11.9 0.0 2.5 3 0 0 3 3 3 0 Phage shock protein B FAD-SLDH PF12318.8 KFM61662.1 - 0.96 9.5 4.9 9.2 6.3 1.2 2.9 2 1 1 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF1151 PF06625.11 KFM61664.1 - 1.2e-28 99.3 13.9 1.2e-28 99.3 13.9 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1151) DUF3987 PF13148.6 KFM61664.1 - 5.6 5.9 7.5 8.3 5.3 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FERM_N PF09379.10 KFM61666.1 - 1.1e-09 38.1 0.1 2.2e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain DUF3219 PF11514.8 KFM61666.1 - 0.043 13.8 0.5 0.1 12.6 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3219) MFS_1 PF07690.16 KFM61668.1 - 1.3e-08 34.2 35.6 1e-06 27.9 9.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 KFM61669.1 - 9.3e-12 44.6 0.0 1.3e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM61669.1 - 0.0047 16.8 0.0 0.0065 16.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KFM61669.1 - 0.025 14.7 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 KFM61670.1 - 1.7e-23 82.2 1.6 3.2e-14 52.5 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM61670.1 - 0.00098 19.1 1.0 0.021 14.8 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFM61670.1 - 0.0056 16.5 0.1 0.45 10.4 0.1 2.9 1 1 1 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KFM61670.1 - 0.023 14.8 0.3 0.22 11.7 0.0 2.9 2 0 0 2 2 2 0 RNA recognition motif SPOC PF07744.13 KFM61671.1 - 1.5e-34 119.1 0.0 2.8e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 SPOC domain Laminin_EGF PF00053.24 KFM61672.1 - 6.2e-87 285.6 208.9 2.4e-11 43.6 11.8 11.7 11 0 0 11 11 11 11 Laminin EGF domain Laminin_N PF00055.17 KFM61672.1 - 7.4e-84 281.0 0.2 7.4e-84 281.0 0.2 2.7 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 KFM61672.1 - 2.4e-28 98.7 0.0 8.4e-28 96.9 0.0 1.9 2 0 0 2 2 2 1 Laminin B (Domain IV) HipN PF18253.1 KFM61672.1 - 0.017 14.8 0.2 0.04 13.6 0.2 1.6 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain Tho1_MOS11_C PF18592.1 KFM61672.1 - 0.13 12.1 2.4 0.18 11.6 0.3 2.4 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Baculo_PEP_C PF04513.12 KFM61672.1 - 0.58 10.2 12.8 0.053 13.6 1.7 3.3 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PMC2NT PF08066.12 KFM61672.1 - 2.3 9.0 6.9 10 6.9 0.6 3.2 2 0 0 2 2 2 0 PMC2NT (NUC016) domain MCPsignal PF00015.21 KFM61672.1 - 5.1 6.9 33.2 0.28 11.0 3.4 3.5 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DDE_1 PF03184.19 KFM61674.1 - 5.1e-17 62.1 0.4 8.3e-17 61.4 0.4 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM61674.1 - 3.6e-12 46.1 0.4 8.1e-12 45.0 0.4 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM61674.1 - 0.0014 18.4 0.0 0.0062 16.3 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3372 PF11852.8 KFM61674.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Ig_3 PF13927.6 KFM61675.1 - 4.6e-67 222.6 15.0 3.4e-09 37.2 0.0 8.0 8 0 0 8 8 8 7 Immunoglobulin domain I-set PF07679.16 KFM61675.1 - 2.2e-56 187.9 2.8 6e-10 39.1 0.0 7.7 8 0 0 8 8 8 7 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM61675.1 - 1.3e-48 163.2 9.5 4.2e-07 30.2 0.1 8.2 8 0 0 8 8 8 7 Immunoglobulin domain ig PF00047.25 KFM61675.1 - 1.4e-47 159.7 12.5 1.5e-08 34.7 0.0 8.2 8 0 0 8 8 8 8 Immunoglobulin domain C2-set_2 PF08205.12 KFM61675.1 - 8.4e-42 141.2 7.3 1.6e-09 37.7 0.1 6.8 7 1 0 7 7 6 5 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM61675.1 - 6e-13 49.0 1.1 0.006 16.9 0.0 6.5 7 0 0 7 7 7 2 Immunoglobulin C1-set domain V-set PF07686.17 KFM61675.1 - 6.6e-12 45.6 12.9 0.034 14.3 0.0 9.6 8 6 2 10 10 9 4 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM61675.1 - 7.5e-12 45.4 0.1 4.5 7.6 0.0 7.9 7 1 0 7 7 7 3 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM61675.1 - 2.3e-11 43.9 0.2 0.077 13.4 0.0 6.6 7 0 0 7 7 6 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set PF05790.15 KFM61675.1 - 1.5e-09 37.9 0.1 0.35 11.1 0.0 6.5 6 0 0 6 6 6 2 Immunoglobulin C2-set domain Ig_C17orf99 PF17736.1 KFM61675.1 - 2.4e-06 27.5 0.0 1.7 8.7 0.0 5.8 5 2 1 6 6 6 2 C17orf99 Ig domain Lep_receptor_Ig PF06328.11 KFM61675.1 - 2.9e-05 23.9 0.7 0.22 11.5 0.0 4.6 4 0 0 4 4 4 1 Ig-like C2-type domain Adeno_E3_CR1 PF02440.15 KFM61675.1 - 0.00042 20.1 0.0 0.31 10.8 0.0 3.4 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 BiPBP_C PF06832.12 KFM61675.1 - 0.0013 18.7 0.0 0.58 10.2 0.0 2.9 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Ig_6 PF18452.1 KFM61675.1 - 0.06 12.9 0.0 0.39 10.3 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain DUF2039 PF10217.9 KFM61676.1 - 0.03 14.7 0.1 0.032 14.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) 7tm_1 PF00001.21 KFM61677.1 - 6e-46 156.9 12.8 7.9e-46 156.5 12.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM61677.1 - 1.1e-13 51.2 13.8 2.1e-13 50.3 13.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM61677.1 - 2.4e-10 40.5 12.4 2.4e-10 40.5 12.4 2.7 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx HTH_32 PF13565.6 KFM61678.1 - 0.00065 20.3 0.0 0.002 18.7 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM61678.1 - 0.0041 16.9 0.1 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM61678.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 KFM61678.1 - 0.024 14.7 0.1 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.6 KFM61678.1 - 0.026 14.3 0.0 0.083 12.6 0.0 1.7 1 1 1 2 2 2 0 DDE superfamily endonuclease HTH_29 PF13551.6 KFM61678.1 - 0.1 12.6 0.0 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix Snapin_Pallidin PF14712.6 KFM61679.1 - 1.8e-26 92.4 6.2 2.9e-26 91.7 6.2 1.3 1 0 0 1 1 1 1 Snapin/Pallidin SesA PF17107.5 KFM61679.1 - 0.00081 19.6 0.3 0.002 18.3 0.2 1.7 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4763 PF15960.5 KFM61679.1 - 0.0021 17.4 1.4 0.003 16.9 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) DUF1811 PF08838.10 KFM61679.1 - 0.011 16.0 1.0 0.014 15.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) MukB PF04310.12 KFM61679.1 - 0.013 15.3 0.2 0.015 15.1 0.2 1.2 1 0 0 1 1 1 0 MukB N-terminal Fib_alpha PF08702.10 KFM61679.1 - 0.013 15.6 4.7 0.023 14.9 4.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ALC PF17527.2 KFM61679.1 - 0.016 14.9 0.2 0.021 14.5 0.2 1.2 1 0 0 1 1 1 0 Phage ALC protein TetR_C_4 PF08359.11 KFM61679.1 - 0.024 14.8 0.6 0.048 13.8 0.3 1.5 1 1 0 1 1 1 0 YsiA-like protein, C-terminal region DUF4201 PF13870.6 KFM61679.1 - 0.032 14.0 6.3 0.047 13.4 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DNA_pol3_gamma3 PF12169.8 KFM61679.1 - 0.034 14.1 0.4 0.052 13.4 0.4 1.4 1 1 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III baeRF_family2 PF18844.1 KFM61679.1 - 0.043 13.9 1.7 0.056 13.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 BORCS8 PF10167.9 KFM61679.1 - 0.062 13.2 2.3 0.09 12.7 2.3 1.3 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 Mod_r PF07200.13 KFM61679.1 - 0.11 12.7 6.4 0.066 13.3 1.2 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 KFM61679.1 - 0.11 12.5 2.6 0.19 11.8 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 KFM61679.1 - 0.15 10.7 2.5 0.17 10.4 2.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4665 PF15679.5 KFM61679.1 - 0.32 11.6 2.7 0.64 10.7 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) DUF16 PF01519.16 KFM61679.1 - 0.47 11.0 4.5 2.2 8.8 3.8 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 DHR10 PF18595.1 KFM61679.1 - 0.52 10.4 9.0 1.7 8.7 9.0 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain CorA PF01544.18 KFM61679.1 - 1.5 8.0 8.4 0.46 9.8 1.3 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Med9 PF07544.13 KFM61679.1 - 5.2 7.2 9.0 7.8 6.7 0.7 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TPH PF13868.6 KFM61683.1 - 4.6e-55 186.6 151.6 4.6e-55 186.6 151.6 2.0 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain Par3_HAL_N_term PF12053.8 KFM61683.1 - 0.03 14.5 1.5 0.12 12.6 1.5 2.1 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins Sld5 PF05916.11 KFM61684.1 - 4.1e-11 43.3 0.1 5.8e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein zf-RING_2 PF13639.6 KFM61685.1 - 1e-11 45.0 8.5 1e-11 45.0 8.5 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM61685.1 - 4.7e-10 39.2 8.0 9.2e-10 38.2 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CUE PF02845.16 KFM61685.1 - 3e-09 36.4 0.7 1e-08 34.7 0.7 2.0 1 0 0 1 1 1 1 CUE domain zf-C3HC4 PF00097.25 KFM61685.1 - 5.3e-07 29.4 7.0 9.7e-07 28.6 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM61685.1 - 5.9e-07 29.2 4.9 9.9e-07 28.5 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM61685.1 - 6.1e-07 29.1 1.3 6.1e-07 29.1 1.3 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFM61685.1 - 1.7e-06 28.0 3.1 3.8e-06 26.8 3.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFM61685.1 - 4.5e-06 26.8 10.4 4.5e-06 26.8 10.4 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain G2BR PF18442.1 KFM61685.1 - 4.5e-06 26.2 1.0 1.1e-05 24.9 1.0 1.7 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) Prok-RING_4 PF14447.6 KFM61685.1 - 1.6e-05 24.6 5.9 3e-05 23.8 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFM61685.1 - 0.00021 21.2 5.0 0.00036 20.4 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFM61685.1 - 0.00043 20.3 2.0 0.00099 19.1 2.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFM61685.1 - 0.0016 18.0 6.4 0.0036 16.9 6.4 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFM61685.1 - 0.0032 17.6 5.0 0.0067 16.6 5.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING SpoIIIAH PF12685.7 KFM61685.1 - 0.043 13.6 1.3 0.068 13.0 1.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein RINGv PF12906.7 KFM61685.1 - 0.22 11.7 6.8 0.54 10.4 6.8 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KFM61685.1 - 0.3 10.9 4.0 1.4 8.8 4.0 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KFM61685.1 - 0.36 11.0 7.4 2.5 8.3 7.3 2.5 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 KFM61685.1 - 1.8 8.9 6.6 4 7.8 6.6 1.6 1 0 0 1 1 1 0 RING-like domain cNMP_binding PF00027.29 KFM61686.1 - 3.6e-18 65.4 0.0 6e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RA PF00788.23 KFM61687.1 - 2.3e-16 60.2 0.0 3.2e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain CRIM PF16978.5 KFM61687.1 - 0.07 13.3 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain RA PF00788.23 KFM61688.1 - 8.2e-08 32.8 0.7 2.7e-07 31.1 0.5 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain FKBP_N_2 PF18023.1 KFM61690.1 - 1.7e-09 37.8 2.2 1.7e-09 37.8 2.2 2.9 2 1 1 3 3 3 1 BDBT FKBP like N-terminal TPR_1 PF00515.28 KFM61690.1 - 3.2e-08 33.0 11.0 4.6e-08 32.6 2.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM61690.1 - 1.9e-06 27.5 7.5 3.9e-06 26.6 2.4 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM61690.1 - 5e-06 26.6 0.8 5e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM61690.1 - 8.6e-05 22.4 1.8 0.00046 20.2 1.6 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM61690.1 - 0.00018 21.7 0.6 0.00051 20.2 0.6 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM61690.1 - 0.00066 20.1 4.1 0.00066 20.1 4.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM61690.1 - 0.0012 18.5 0.5 0.0012 18.5 0.5 2.9 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 KFM61690.1 - 0.013 16.3 1.4 0.031 15.1 1.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM61690.1 - 0.036 14.7 1.2 0.083 13.6 1.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM61690.1 - 0.052 13.8 3.2 0.12 12.6 3.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KFM61690.1 - 0.055 13.5 3.0 0.092 12.8 2.1 1.9 1 1 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat CLZ PF16526.5 KFM61690.1 - 0.19 12.1 1.6 0.52 10.7 1.6 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoO PF09769.9 KFM61691.1 - 5.6 6.9 7.7 1.4 8.9 0.6 3.3 2 1 0 2 2 2 0 Apolipoprotein O Fascin PF06268.13 KFM61692.1 - 1.7e-82 272.9 3.5 3.3e-27 94.9 0.0 4.2 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.12 KFM61692.1 - 2.9e-17 63.0 0.1 0.005 16.6 0.0 6.5 1 1 7 8 8 8 7 FRG1-like domain RicinB_lectin_2 PF14200.6 KFM61692.1 - 3.8e-07 30.7 4.1 4 8.2 0.0 5.7 3 2 2 6 6 6 3 Ricin-type beta-trefoil lectin domain-like DUF569 PF04601.13 KFM61692.1 - 0.0004 20.1 0.0 0.077 12.7 0.0 4.1 4 1 1 5 5 5 1 Domain of unknown function (DUF569) Ntox17 PF15524.6 KFM61692.1 - 0.12 12.6 0.1 20 5.6 0.0 3.2 3 0 0 3 3 3 0 Novel toxin 17 DUF773 PF05600.12 KFM61693.1 - 5.4e-169 563.2 3.8 6.1e-169 563.0 3.8 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 BrkDBD PF09607.10 KFM61693.1 - 0.14 11.9 0.7 0.64 9.8 0.1 2.2 2 0 0 2 2 2 0 Brinker DNA-binding domain SRR1 PF07985.12 KFM61694.1 - 4.5e-17 61.8 0.0 1e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 SRR1 Arylesterase PF01731.20 KFM61694.1 - 0.036 14.2 0.3 1.2 9.4 0.0 2.7 2 1 0 2 2 2 0 Arylesterase Sugar_tr PF00083.24 KFM61697.1 - 1.5e-68 231.8 25.4 1.7e-68 231.6 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM61697.1 - 3.5e-23 82.1 29.9 8.2e-22 77.6 25.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1118 PF06549.12 KFM61697.1 - 0.22 11.9 6.6 3.6 7.9 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1118) Ets PF00178.22 KFM61698.1 - 1.8e-37 127.7 1.0 2.8e-37 127.0 1.0 1.3 1 0 0 1 1 1 1 Ets-domain TMEM192 PF14802.6 KFM61699.1 - 3.1e-60 203.2 2.0 3.5e-60 203.0 2.0 1.0 1 0 0 1 1 1 1 TMEM192 family Soc PF16855.5 KFM61700.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Small outer capsid protein Lebercilin PF15619.6 KFM61702.1 - 0.00026 20.7 5.8 0.0003 20.5 5.8 1.0 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 KFM61702.1 - 0.0035 17.8 3.9 0.0039 17.7 3.9 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region GAS PF13851.6 KFM61702.1 - 0.0043 16.4 4.2 0.0046 16.3 4.2 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4140 PF13600.6 KFM61702.1 - 0.006 17.0 0.5 0.0072 16.7 0.5 1.1 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) TSNAXIP1_N PF15739.5 KFM61702.1 - 0.0079 16.6 0.9 0.0092 16.3 0.9 1.1 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus Noelin-1 PF12308.8 KFM61702.1 - 0.058 13.4 2.2 0.066 13.2 2.2 1.1 1 0 0 1 1 1 0 Neurogenesis glycoprotein AAA_23 PF13476.6 KFM61702.1 - 0.13 12.7 2.5 0.14 12.6 2.5 1.0 1 0 0 1 1 1 0 AAA domain Prominin PF05478.11 KFM61702.1 - 0.17 9.8 1.9 0.18 9.7 1.9 1.0 1 0 0 1 1 1 0 Prominin zf-CCCH PF00642.24 KFM61703.1 - 4.3e-23 80.7 14.7 1.2e-11 44.3 3.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM61703.1 - 6.8e-12 45.0 13.8 2.7e-07 30.4 2.8 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFM61703.1 - 5.8e-09 35.5 12.8 8e-05 22.3 1.7 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFM61703.1 - 0.00033 21.0 12.7 0.066 13.7 1.5 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KFM61703.1 - 0.00077 20.1 8.0 0.1 13.3 1.1 2.3 1 1 1 2 2 2 2 Torus domain oligo_HPY PF08352.12 KFM61703.1 - 0.5 10.9 6.9 4.2 8.0 0.7 2.5 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region CBM_14 PF01607.24 KFM61705.1 - 4.4e-09 36.4 5.4 6.9e-09 35.7 5.4 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 KFM61706.1 - 2.3e-09 37.3 5.2 3.5e-09 36.7 5.2 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DNA_ligase_IV PF11411.8 KFM61706.1 - 0.18 11.9 0.6 0.4 10.9 0.6 1.5 1 0 0 1 1 1 0 DNA ligase IV CBM_14 PF01607.24 KFM61708.1 - 8.5e-10 38.7 5.1 1.4e-09 38.0 5.1 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 KFM61709.1 - 4.3e-09 36.4 9.1 6.9e-09 35.7 9.1 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain RNA_pol_Rpc34 PF05158.12 KFM61710.1 - 0.029 13.8 0.0 0.029 13.8 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit PH PF00169.29 KFM61711.1 - 1.8e-15 57.3 0.1 3.8e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 KFM61711.1 - 1.4e-05 25.1 0.0 4.2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM61711.1 - 0.001 19.5 0.5 0.0021 18.5 0.5 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFM61711.1 - 0.0019 18.4 0.0 0.006 16.8 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain DUF1579 PF07617.11 KFM61711.1 - 0.14 12.1 0.2 0.54 10.2 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1579) FHA PF00498.26 KFM61712.1 - 0.013 15.9 0.6 0.056 13.8 0.1 2.4 2 0 0 2 2 2 0 FHA domain Yop-YscD_cpl PF16697.5 KFM61712.1 - 0.016 15.5 0.7 0.084 13.2 0.0 2.7 3 0 0 3 3 3 0 Inner membrane component of T3SS, cytoplasmic domain fn3 PF00041.21 KFM61713.1 - 1.1e-17 64.1 0.6 1.7e-17 63.5 0.6 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM61713.1 - 7.5e-06 26.4 0.1 1.2e-05 25.8 0.1 1.2 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain I-set PF07679.16 KFM61713.1 - 0.00014 21.9 0.0 0.00029 20.8 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFM61713.1 - 0.0042 17.2 0.0 0.0084 16.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM61713.1 - 0.02 15.1 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM61713.1 - 0.063 13.9 1.3 0.1 13.2 0.0 2.0 2 1 0 2 2 2 0 Immunoglobulin domain F5_F8_type_C PF00754.25 KFM61713.1 - 0.068 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain BTG PF07742.12 KFM61714.1 - 1.5e-38 131.2 0.0 2e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 BTG family Cas6_N PF17952.1 KFM61716.1 - 0.069 13.4 0.0 0.075 13.3 0.0 1.2 1 0 0 1 1 1 0 Cas6 N-terminal domain Myelin_PLP PF01275.19 KFM61717.1 - 1.8e-67 227.6 8.5 2.3e-67 227.3 8.5 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF998 PF06197.13 KFM61717.1 - 0.0083 15.7 5.8 0.0083 15.7 5.8 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF998) DUF4577 PF15145.6 KFM61717.1 - 0.065 13.3 0.5 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) SIT PF15330.6 KFM61717.1 - 0.26 11.8 2.0 1.5 9.3 0.2 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT FtsX PF02687.21 KFM61717.1 - 0.93 10.0 15.6 3.1 8.3 10.1 2.9 2 1 0 2 2 2 0 FtsX-like permease family DUF1361 PF07099.11 KFM61717.1 - 0.98 9.4 7.6 0.23 11.4 0.7 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1361) DUF4704 PF15787.5 KFM61720.1 - 1.3e-117 392.1 5.3 3.8e-117 390.5 5.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 KFM61720.1 - 1.2e-78 262.6 6.4 1.2e-78 262.6 6.4 2.5 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1088) Laminin_G_3 PF13385.6 KFM61720.1 - 1.9e-11 44.4 0.0 5.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 KFM61720.1 - 0.00086 19.4 0.0 0.0035 17.4 0.0 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Mab-21 PF03281.14 KFM61721.1 - 6.2e-99 331.0 0.0 7.4e-99 330.8 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein SNF PF00209.18 KFM61722.1 - 2.4e-186 620.5 38.2 5.2e-186 619.4 38.2 1.5 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DA1-like PF12315.8 KFM61722.1 - 0.027 13.9 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein DA1 Antimicrobial_3 PF08025.11 KFM61722.1 - 0.044 13.7 0.1 0.08 12.9 0.1 1.4 1 0 0 1 1 1 0 Spider antimicrobial peptide Neisseria_TspB PF05616.13 KFM61722.1 - 0.2 10.1 0.1 0.28 9.6 0.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RRM_1 PF00076.22 KFM61723.1 - 1.6e-35 120.7 0.4 5.7e-17 61.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM61723.1 - 7.5e-09 35.6 0.1 0.0026 17.8 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM61723.1 - 0.0022 17.9 0.1 2.6 8.1 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 KFM61723.1 - 0.0058 16.5 0.1 0.035 14.1 0.0 2.0 2 0 0 2 2 2 1 RL domain RRM_3 PF08777.11 KFM61723.1 - 0.11 12.6 0.2 7.8 6.6 0.1 2.3 2 0 0 2 2 2 0 RNA binding motif LSM PF01423.22 KFM61724.1 - 1.6e-12 46.9 2.1 2e-12 46.6 2.1 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KFM61724.1 - 0.042 13.9 0.1 0.06 13.5 0.1 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain SM-ATX PF14438.6 KFM61724.1 - 0.047 13.8 0.1 0.069 13.3 0.1 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 KFM61724.1 - 0.093 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain pXO2-72 PF17443.2 KFM61724.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein pXO2-72 FAM76 PF16046.5 KFM61725.1 - 1.4e-113 379.2 33.7 1.6e-113 379.0 33.7 1.0 1 0 0 1 1 1 1 FAM76 protein RAP1 PF07218.11 KFM61725.1 - 0.002 16.5 5.6 0.0026 16.1 5.6 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 KFM61725.1 - 0.02 13.5 17.6 0.025 13.2 17.6 1.0 1 0 0 1 1 1 0 Macoilin family ER-remodelling PF14755.6 KFM61725.1 - 0.075 13.3 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Intracellular membrane remodeller Filament_head PF04732.14 KFM61725.1 - 0.28 12.1 11.9 0.5 11.3 11.9 1.3 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region DZR PF12773.7 KFM61725.1 - 0.4 10.7 28.5 1.5 8.9 4.0 3.6 1 1 2 3 3 3 0 Double zinc ribbon Miga PF10265.9 KFM61725.1 - 2.1 7.2 11.1 2.6 6.9 11.1 1.1 1 0 0 1 1 1 0 Mitoguardin Presenilin PF01080.17 KFM61725.1 - 2.7 6.6 4.5 3.3 6.4 4.5 1.2 1 0 0 1 1 1 0 Presenilin DUF2614 PF11023.8 KFM61725.1 - 5.4 7.2 8.8 2.4 8.3 1.2 2.4 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF4371 PF14291.6 KFM61726.1 - 0.00019 21.2 0.0 0.00022 20.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KFM61726.1 - 0.004 17.0 0.1 0.0043 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ADH_zinc_N_2 PF13602.6 KFM61727.1 - 8.2e-21 75.4 0.0 1.1e-20 75.1 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFM61727.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HSNSD PF12062.8 KFM61730.1 - 1.7e-225 749.4 0.1 3.1e-225 748.5 0.0 1.4 2 0 0 2 2 2 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFM61730.1 - 1.8e-39 135.9 0.0 2.9e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM61730.1 - 2.1e-10 41.3 0.1 0.00022 21.7 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family Trypsin PF00089.26 KFM61731.1 - 3e-53 180.9 0.0 4.2e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFM61731.1 - 1.6e-20 73.5 0.0 3.4e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 KFM61731.1 - 8.9e-10 38.6 10.3 8.9e-10 38.6 10.3 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 KFM61731.1 - 8.8e-08 32.5 0.0 1.2e-06 28.9 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFM61731.1 - 5.3e-07 30.7 0.0 9.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain ELO PF01151.18 KFM61732.1 - 2.8e-49 167.9 29.1 3.1e-49 167.8 29.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ras PF00071.22 KFM61734.1 - 1.6e-54 183.9 0.0 1.9e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM61734.1 - 6.1e-22 78.1 0.0 8.7e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM61734.1 - 8.6e-10 38.3 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM61734.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PI-PLC-X PF00388.19 KFM61735.1 - 2e-63 212.3 0.0 3.9e-63 211.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFM61735.1 - 3.7e-40 136.8 0.7 8.2e-40 135.7 0.7 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFM61735.1 - 7.1e-12 45.7 3.2 2.5e-11 43.9 0.3 2.5 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 KFM61735.1 - 5.2e-05 23.6 0.1 0.089 13.3 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 KFM61735.1 - 0.00055 19.8 0.3 0.0019 18.0 0.3 2.0 1 1 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KFM61735.1 - 0.0011 18.3 0.1 0.017 14.6 0.0 3.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFM61735.1 - 0.0029 17.4 0.2 0.71 10.0 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain GDPD PF03009.17 KFM61735.1 - 0.003 17.3 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PH_12 PF16457.5 KFM61735.1 - 0.021 15.4 0.0 0.074 13.6 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain PH PF00169.29 KFM61735.1 - 0.093 13.3 0.0 0.28 11.7 0.0 2.0 1 1 0 1 1 1 0 PH domain TEP1_N PF05386.11 KFM61735.1 - 0.11 12.2 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 TEP1 N-terminal domain CATSPERB PF15149.6 KFM61735.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family PI-PLC-X PF00388.19 KFM61736.1 - 9.5e-59 197.1 0.0 1.9e-58 196.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFM61736.1 - 1.1e-40 138.5 0.1 3.1e-40 137.1 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KFM61736.1 - 9.3e-18 64.4 0.0 2.4e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 KFM61736.1 - 7.8e-12 45.5 5.8 9.1e-12 45.3 1.0 2.8 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 KFM61736.1 - 0.00027 20.3 0.4 0.003 17.0 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KFM61736.1 - 0.00066 20.1 0.5 0.0041 17.6 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.6 KFM61736.1 - 0.00083 19.2 0.0 0.0029 17.4 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFM61736.1 - 0.012 15.4 4.4 0.87 9.7 0.0 4.3 5 0 0 5 5 5 0 EF-hand domain EF-hand_8 PF13833.6 KFM61736.1 - 0.19 11.6 0.7 4.8 7.1 0.0 3.4 3 1 1 4 4 4 0 EF-hand domain pair MazG-like PF12643.7 KFM61737.1 - 8.3e-11 42.0 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 KFM61737.1 - 7.1e-07 29.3 0.3 1.7e-06 28.1 0.3 1.6 1 1 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain TPR_11 PF13414.6 KFM61739.1 - 2.8e-08 33.3 0.1 2.8e-08 33.3 0.1 1.0 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 KFM61739.1 - 3.5e-05 23.4 0.0 0.27 11.1 0.1 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM61739.1 - 0.00024 21.2 0.3 0.00037 20.7 0.0 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM61739.1 - 0.00026 21.6 0.0 0.00026 21.6 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM61739.1 - 0.002 18.1 0.0 0.79 10.0 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM61739.1 - 0.0081 16.0 0.1 3.9 7.5 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM61739.1 - 0.0085 16.6 0.0 0.0085 16.6 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM61739.1 - 0.024 14.8 0.1 5.6 7.4 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM61739.1 - 0.024 14.6 0.2 1.4 9.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Actin PF00022.19 KFM61741.1 - 1.9e-151 504.3 0.0 6e-151 502.7 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 KFM61743.1 - 1.2e-145 485.2 0.0 3.9e-145 483.5 0.0 1.6 1 1 0 1 1 1 1 Actin CS PF04969.16 KFM61744.1 - 2.6e-07 31.6 0.2 4.3e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 CS domain RE_BsaWI PF18643.1 KFM61744.1 - 9e-05 22.3 0.1 0.00017 21.4 0.1 1.4 1 0 0 1 1 1 1 BsaWI restriction endonuclease type 2 CRAL_TRIO PF00650.20 KFM61745.1 - 7.8e-24 84.2 0.3 1.1e-23 83.7 0.3 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Peptidase_C6 PF00851.18 KFM61745.1 - 0.026 13.5 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Helper component proteinase CRAL_TRIO_2 PF13716.6 KFM61745.1 - 0.038 14.2 0.1 0.077 13.2 0.1 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain 7tm_1 PF00001.21 KFM61746.1 - 1.3e-41 142.7 4.2 1.4e-41 142.6 4.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM61746.1 - 0.00027 20.7 1.7 0.00045 19.9 1.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFM61746.1 - 0.0013 18.2 1.8 0.0016 17.9 1.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFM61746.1 - 0.0046 16.7 1.0 0.0065 16.2 0.0 1.6 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFM61746.1 - 0.021 14.2 1.1 0.026 13.9 1.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx PH PF00169.29 KFM61748.1 - 1.1e-14 54.8 0.6 1.1e-14 54.8 0.6 3.4 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 KFM61748.1 - 0.093 13.1 5.1 0.17 12.3 0.1 3.6 2 1 0 2 2 2 0 Pleckstrin homology domain Ribosomal_S15 PF00312.22 KFM61748.1 - 0.23 11.7 13.4 0.023 14.9 3.1 3.4 2 0 0 2 2 2 0 Ribosomal protein S15 Baculo_PEP_C PF04513.12 KFM61748.1 - 1.7 8.6 25.8 2.9 7.9 0.0 6.5 6 1 0 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bestrophin PF01062.21 KFM61751.1 - 2.7e-42 145.2 0.3 3.1e-42 145.0 0.3 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PAN_1 PF00024.26 KFM61752.1 - 1.6e-22 79.2 34.5 1.8e-07 31.0 1.9 4.6 4 0 0 4 4 4 4 PAN domain PAN_4 PF14295.6 KFM61752.1 - 1.4e-07 31.3 28.1 0.011 15.6 1.0 4.7 4 0 0 4 4 4 4 PAN domain DUF1363 PF07101.11 KFM61754.1 - 0.089 13.1 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) DUF659 PF04937.15 KFM61755.1 - 0.0002 21.3 0.2 0.00067 19.6 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM61755.1 - 0.00026 20.7 0.3 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) HTH_48 PF17906.1 KFM61755.1 - 0.0026 17.9 0.0 0.023 14.8 0.0 2.7 2 0 0 2 2 2 1 HTH domain in Mos1 transposase Aldo_ket_red PF00248.21 KFM61756.1 - 2.1e-10 40.3 0.0 2.3e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KFM61757.1 - 7.9e-08 31.8 0.0 9e-08 31.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF659 PF04937.15 KFM61758.1 - 0.0034 17.3 0.3 0.0085 16.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM61758.1 - 0.011 15.5 0.1 0.055 13.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM61758.1 - 0.018 14.9 0.1 0.28 11.0 0.1 2.9 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region Ank_2 PF12796.7 KFM61761.1 - 1.3e-43 147.4 1.0 1.9e-15 57.2 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM61761.1 - 3.8e-41 138.9 2.4 8.7e-10 38.9 0.0 5.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFM61761.1 - 3.6e-38 128.4 6.4 2.2e-06 27.9 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KFM61761.1 - 1.3e-33 111.2 0.1 4.4e-05 23.5 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFM61761.1 - 2.6e-33 113.6 3.8 6.6e-08 32.7 0.1 6.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) SAM_1 PF00536.30 KFM61761.1 - 1.9e-28 98.7 0.3 2.3e-15 56.8 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM61761.1 - 1.7e-25 88.9 0.5 1.2e-11 44.6 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) PID PF00640.23 KFM61761.1 - 1.4e-18 67.2 2.2 4e-18 65.8 2.2 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 KFM61761.1 - 0.00014 21.8 0.5 0.00029 20.8 0.5 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFM61761.1 - 0.0013 18.8 0.5 0.0029 17.7 0.5 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain IQCJ-SCHIP1 PF15157.6 KFM61761.1 - 2 8.2 6.4 0.5 10.2 0.1 2.8 2 1 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif 7tm_2 PF00002.24 KFM61762.1 - 2.7e-34 118.5 18.9 3.6e-34 118.1 18.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF63 PF01889.17 KFM61762.1 - 0.52 10.5 12.2 0.45 10.6 4.7 2.2 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 DUF4071 PF13281.6 KFM61763.1 - 8.7e-163 541.6 0.5 8.7e-163 541.6 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 KFM61763.1 - 8.6e-65 218.7 0.0 3.4e-64 216.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM61763.1 - 1.4e-41 142.6 0.0 4.3e-41 140.9 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_2 PF07647.17 KFM61763.1 - 0.00016 21.7 0.1 0.00039 20.5 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 KFM61763.1 - 0.00074 18.4 0.2 0.0026 16.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFM61763.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 KFM61763.1 - 0.038 13.5 0.1 0.97 8.9 0.0 2.8 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL PI3K_P85_iSH2 PF16454.5 KFM61763.1 - 0.064 12.8 4.1 0.31 10.6 4.1 2.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain His_binding PF02098.16 KFM61763.1 - 0.14 12.2 0.1 3.7 7.6 0.1 2.7 2 0 0 2 2 2 0 Tick histamine binding protein bZIP_1 PF00170.21 KFM61763.1 - 3.1 8.0 8.2 2.6 8.2 5.6 2.3 2 0 0 2 2 2 0 bZIP transcription factor 3HCDH_N PF02737.18 KFM61764.1 - 4.3e-38 131.0 0.0 6.2e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C3HC4_3 PF13920.6 KFM61764.1 - 2.9e-13 49.4 17.8 5.4e-13 48.6 17.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NAD_binding_2 PF03446.15 KFM61764.1 - 2e-08 34.6 0.0 4.8e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KFM61764.1 - 5.9e-06 26.3 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Prok-RING_4 PF14447.6 KFM61764.1 - 2.6e-05 24.0 16.9 4.6e-05 23.2 16.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 F420_oxidored PF03807.17 KFM61764.1 - 0.00011 22.8 0.0 0.00028 21.4 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 KFM61764.1 - 0.0014 19.1 0.1 0.0027 18.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFM61764.1 - 0.0016 18.1 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KFM61764.1 - 0.0036 17.7 0.0 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KFM61764.1 - 0.004 16.7 0.0 0.0063 16.1 0.0 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-RING_2 PF13639.6 KFM61764.1 - 0.0051 17.1 18.0 0.0099 16.2 18.0 1.5 1 0 0 1 1 1 1 Ring finger domain AlaDh_PNT_C PF01262.21 KFM61764.1 - 0.0056 16.0 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain zf-C3HC4_2 PF13923.6 KFM61764.1 - 0.021 14.7 18.6 0.037 13.9 18.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pyr_redox_2 PF07992.14 KFM61764.1 - 0.034 13.4 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFM61764.1 - 0.039 14.2 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain zf-RING_5 PF14634.6 KFM61764.1 - 0.041 13.8 16.5 0.096 12.7 16.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Shikimate_DH PF01488.20 KFM61764.1 - 0.05 13.7 0.3 0.17 12.0 0.0 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAA_assoc_2 PF16193.5 KFM61764.1 - 0.062 13.6 1.0 5.3 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA C-terminal domain Sacchrp_dh_NADP PF03435.18 KFM61764.1 - 0.063 13.5 0.0 0.21 11.8 0.0 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_C PF03720.15 KFM61764.1 - 0.075 13.5 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain zf-P11 PF03854.14 KFM61764.1 - 0.11 12.2 11.9 0.21 11.3 11.9 1.5 1 0 0 1 1 1 0 P-11 zinc finger adh_short PF00106.25 KFM61764.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox_3 PF13738.6 KFM61764.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM61764.1 - 0.19 10.9 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Sulfatase PF00884.23 KFM61765.1 - 0.07 12.5 0.0 0.07 12.5 0.0 1.0 1 0 0 1 1 1 0 Sulfatase Sulfatase PF00884.23 KFM61766.1 - 1.6e-42 146.0 0.4 1.9e-42 145.8 0.4 1.0 1 0 0 1 1 1 1 Sulfatase GATase_7 PF13537.6 KFM61766.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain AD PF09793.9 KFM61767.1 - 3.4e-25 88.0 0.0 4.9e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 KFM61767.1 - 0.082 12.4 0.1 0.19 11.3 0.1 1.5 1 1 0 1 1 1 0 Gemin6 protein Aldo_ket_red PF00248.21 KFM61768.1 - 1.7e-14 53.8 0.0 1.9e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KFM61769.1 - 2.1e-09 37.0 0.0 2.7e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family THF_DHG_CYH_C PF02882.19 KFM61770.1 - 6.8e-64 214.0 3.4 9.4e-64 213.5 3.4 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFM61770.1 - 2e-38 131.2 0.2 2.9e-38 130.7 0.2 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain C2 PF00168.30 KFM61772.1 - 1.4e-09 38.1 0.1 1.6e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 C2 domain Fascin PF06268.13 KFM61775.1 - 5.4e-25 87.8 0.2 3.9e-11 43.2 0.0 2.3 1 1 0 2 2 2 2 Fascin domain FRG1 PF06229.12 KFM61775.1 - 2.1e-11 43.9 1.7 1.1e-05 25.2 0.1 3.2 1 1 2 3 3 3 3 FRG1-like domain Sipho_tail PF05709.11 KFM61775.1 - 0.0069 15.8 0.1 0.034 13.6 0.0 2.0 1 1 1 2 2 2 1 Phage tail protein FGF PF00167.18 KFM61775.1 - 0.044 13.9 0.0 0.15 12.2 0.0 1.8 1 1 0 1 1 1 0 Fibroblast growth factor DAGK_cat PF00781.24 KFM61776.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ribosomal_L18 PF17135.4 KFM61778.1 - 5.5e-88 293.3 0.9 6.1e-88 293.1 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KFM61778.1 - 0.006 17.2 0.1 0.024 15.3 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ras PF00071.22 KFM61779.1 - 4.2e-29 101.2 0.1 4.8e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM61779.1 - 1.3e-12 48.0 0.0 2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM61779.1 - 8.6e-10 38.3 0.0 1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM61779.1 - 7.3e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFM61779.1 - 8.7e-05 22.6 0.0 0.2 11.7 0.0 2.2 2 0 0 2 2 2 2 Dynamin family Gtr1_RagA PF04670.12 KFM61779.1 - 0.00054 19.4 0.1 0.001 18.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM61779.1 - 0.0012 18.4 0.1 0.095 12.2 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFM61779.1 - 0.0017 17.8 0.0 0.0039 16.7 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KFM61779.1 - 0.0029 17.6 0.1 0.0058 16.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 KFM61779.1 - 0.021 14.0 0.0 0.6 9.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 KFM61779.1 - 0.067 13.6 0.2 0.1 13.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 KFM61779.1 - 0.1 12.2 0.1 8.7 5.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KFM61779.1 - 0.15 12.0 0.2 0.96 9.4 0.0 2.1 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 KFM61779.1 - 0.15 11.4 0.2 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family dsDNA_bind PF01984.20 KFM61780.1 - 9.6e-28 96.7 6.3 2e-27 95.7 6.3 1.5 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Aminotran_1_2 PF00155.21 KFM61780.1 - 1.7e-21 76.8 0.0 2.4e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II LON_substr_bdg PF02190.16 KFM61782.1 - 4e-22 79.1 0.0 5.3e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 KFM61782.1 - 1.1e-08 35.2 0.3 2.1e-08 34.3 0.3 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NTP_transf_2 PF01909.23 KFM61784.1 - 5.7e-05 23.3 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DAO PF01266.24 KFM61785.1 - 3.5e-37 128.8 0.0 3.9e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFM61785.1 - 1.7e-06 27.5 0.2 0.003 16.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 KFM61785.1 - 8.7e-06 25.2 0.0 0.0085 15.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM61785.1 - 0.00037 19.8 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFM61785.1 - 0.0043 17.3 0.2 0.021 15.1 0.1 2.1 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.14 KFM61785.1 - 0.0061 15.3 0.2 0.44 9.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KFM61785.1 - 0.008 15.3 0.0 0.019 14.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 KFM61785.1 - 0.014 15.4 0.1 0.039 14.0 0.1 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KFM61785.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KFM61785.1 - 0.053 13.5 0.1 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KFM61785.1 - 0.14 11.0 0.1 5.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 KFM61785.1 - 0.16 12.5 0.4 4.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAO_M PF16350.5 KFM61786.1 - 6.3e-18 64.9 0.1 8.8e-18 64.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T PF01571.21 KFM61787.1 - 2.7e-38 131.8 0.0 3.3e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KFM61787.1 - 2.3e-16 59.5 0.0 4.4e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 KFM61787.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family Neur_chan_memb PF02932.16 KFM61788.1 - 1.5e-72 244.5 0.1 2e-72 244.1 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM61788.1 - 2.6e-27 95.7 0.4 3.4e-27 95.3 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain BCIP PF13862.6 KFM61790.1 - 2.5e-22 79.7 0.0 3e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein HA2 PF04408.23 KFM61791.1 - 2.9e-23 82.2 0.1 7.1e-23 80.9 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFM61791.1 - 8.6e-23 80.5 0.0 2.3e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFM61791.1 - 2e-12 47.4 0.0 4.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM61791.1 - 1.6e-06 28.0 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KFM61791.1 - 0.0001 22.7 0.1 0.00021 21.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM61791.1 - 0.00059 19.6 0.1 0.001 18.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM61791.1 - 0.00061 20.1 0.1 0.0029 17.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 KFM61791.1 - 0.00061 19.5 0.1 0.0019 17.9 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KFM61791.1 - 0.0047 16.9 0.1 0.0093 15.9 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 KFM61791.1 - 0.0095 15.9 0.0 2.4 8.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFM61791.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 KFM61791.1 - 0.027 14.2 0.1 3.4 7.4 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 KFM61791.1 - 0.032 14.8 0.0 0.19 12.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 KFM61791.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFM61791.1 - 0.093 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Toxin_9 PF02819.15 KFM61793.1 - 0.12 12.6 16.3 0.16 12.3 16.3 1.2 1 0 0 1 1 1 0 Spider toxin Toxin_29 PF08116.11 KFM61793.1 - 0.14 12.1 12.7 0.2 11.7 12.7 1.2 1 0 0 1 1 1 0 PhTx neurotoxin family Toxin_35 PF10530.9 KFM61794.1 - 0.0012 18.8 13.1 0.0036 17.2 13.1 1.7 1 1 0 1 1 1 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Agouti PF05039.12 KFM61794.1 - 0.0014 19.3 5.3 0.0016 19.1 5.3 1.1 1 0 0 1 1 1 1 Agouti protein Toxin_9 PF02819.15 KFM61794.1 - 0.0084 16.4 11.6 0.014 15.6 11.6 1.4 1 1 0 1 1 1 1 Spider toxin Inhibitor_I53 PF11714.8 KFM61794.1 - 0.022 14.9 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Toxin_7 PF05980.12 KFM61794.1 - 0.22 11.8 12.7 0.43 10.9 12.7 1.6 1 1 0 1 1 1 0 Toxin 7 Toxin_9 PF02819.15 KFM61795.1 - 9.2e-05 22.6 12.5 0.00012 22.3 12.5 1.2 1 0 0 1 1 1 1 Spider toxin MotB_plug PF13677.6 KFM61795.1 - 0.19 11.3 0.1 0.27 10.9 0.1 1.2 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Conotoxin PF02950.17 KFM61796.1 - 0.00024 22.1 3.1 0.00035 21.5 3.1 1.2 1 0 0 1 1 1 1 Conotoxin ODV-E18 PF10717.9 KFM61796.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Phage_Gp23 PF10669.9 KFM61796.1 - 0.2 12.0 0.0 0.23 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Somatomedin_B PF01033.17 KFM61797.1 - 0.043 14.2 11.5 0.043 14.2 11.5 3.4 3 0 0 3 3 3 0 Somatomedin B domain Spidroin_N PF16763.5 KFM61798.1 - 3.3e-44 149.9 6.2 7.6e-44 148.7 6.2 1.6 1 0 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term DUF1840 PF08895.11 KFM61798.1 - 0.13 12.6 0.4 0.58 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Coiled PF05710.12 KFM61798.1 - 0.15 12.9 0.1 0.15 12.9 0.1 3.6 1 1 1 2 2 2 0 Coiled coil RNase_H PF00075.24 KFM61799.1 - 7.8e-14 52.1 0.7 3.4e-13 50.0 0.9 2.0 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.6 KFM61799.1 - 9.9e-06 25.4 0.2 1.7e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Spidroin_N PF16763.5 KFM61802.1 - 1.1e-45 154.7 6.4 1.4e-45 154.4 6.4 1.1 1 0 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term DUF1840 PF08895.11 KFM61802.1 - 0.0053 17.1 0.2 0.014 15.7 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1840) Coiled PF05710.12 KFM61802.1 - 0.0065 17.3 2.7 0.0065 17.3 2.7 2.0 1 1 1 2 2 2 1 Coiled coil mRNA_cap_enzyme PF01331.19 KFM61803.1 - 4.5e-53 180.0 1.0 5.1e-53 179.8 0.2 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KFM61803.1 - 2.4e-19 70.0 0.0 5.1e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 KFM61804.1 - 8.6e-13 48.3 0.0 1.4e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain mRNA_cap_enzyme PF01331.19 KFM61804.1 - 2.3e-07 30.8 0.0 3.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Y_phosphatase PF00102.27 KFM61804.1 - 0.023 14.3 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFM61804.1 - 0.036 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM61804.1 - 0.06 13.5 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFM61804.1 - 0.23 11.4 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family WD40 PF00400.32 KFM61805.1 - 4.9e-19 68.3 4.8 2.1e-09 37.8 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM61805.1 - 4.9e-05 23.5 0.0 0.0048 17.2 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM61805.1 - 0.0014 17.3 0.0 0.0036 16.0 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFM61805.1 - 0.046 12.7 0.9 0.13 11.2 0.6 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFM61805.1 - 0.11 11.3 0.0 0.27 9.9 0.0 1.7 2 0 0 2 2 2 0 Nup133 N terminal like PQQ_3 PF13570.6 KFM61805.1 - 0.11 13.0 1.2 3.3 8.3 0.2 3.1 2 1 0 2 2 2 0 PQQ-like domain ANAPC4_WD40 PF12894.7 KFM61806.1 - 1.3e-05 25.4 0.0 0.096 13.0 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM61806.1 - 8.3e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KFM61806.1 - 0.0098 16.7 0.0 0.59 11.1 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Mcl1_mid PF12341.8 KFM61807.1 - 2.6e-81 273.2 0.0 3.9e-81 272.7 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region HMG_box PF00505.19 KFM61807.1 - 2.6e-07 30.9 1.3 1.1e-06 29.0 0.5 2.4 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM61807.1 - 0.015 15.9 0.2 0.053 14.1 0.2 2.0 1 0 0 1 1 1 0 HMG-box domain GNAT_acetyltr_2 PF13718.6 KFM61808.1 - 8.3e-89 296.9 0.0 2.3e-88 295.4 0.0 1.7 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 KFM61808.1 - 1.6e-59 200.7 0.0 6e-59 198.9 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KFM61808.1 - 1.5e-25 88.9 0.1 9e-25 86.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.6 KFM61808.1 - 8.5e-13 48.5 0.0 1.7e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.7 KFM61808.1 - 0.013 15.9 0.0 0.049 14.1 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM61808.1 - 0.017 15.4 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Sigma70_r4_2 PF08281.12 KFM61808.1 - 0.07 12.8 0.1 20 4.9 0.0 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 DUF4911 PF16256.5 KFM61808.1 - 0.079 12.9 0.7 2.2 8.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) Homeodomain PF00046.29 KFM61810.1 - 7.2e-21 73.8 6.8 1.3e-20 72.9 6.8 1.5 1 0 0 1 1 1 1 Homeodomain Thioredoxin_11 PF18078.1 KFM61810.1 - 0.091 12.9 1.3 0.16 12.1 1.3 1.3 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain CENP-B_dimeris PF09026.10 KFM61811.1 - 0.38 11.2 6.6 0.79 10.1 6.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ski_Sno PF02437.17 KFM61812.1 - 4.7e-37 126.0 0.0 6.3e-37 125.6 0.0 1.1 1 0 0 1 1 1 1 SKI/SNO/DAC family Ank_2 PF12796.7 KFM61813.1 - 1.8e-32 111.7 5.1 1.2e-14 54.6 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM61813.1 - 3.2e-30 104.1 2.8 2.4e-07 31.2 0.0 5.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFM61813.1 - 9.7e-29 98.5 7.2 1.7e-05 25.1 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KFM61813.1 - 7.5e-24 81.2 8.7 0.0028 18.0 0.1 8.2 7 1 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KFM61813.1 - 3.1e-21 75.1 4.5 3e-05 24.2 0.1 5.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) DCB PF16213.5 KFM61813.1 - 0.022 14.4 0.0 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 An_peroxidase PF03098.15 KFM61815.1 - 4.3e-102 342.4 0.0 5.2e-102 342.1 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase DDE_1 PF03184.19 KFM61816.1 - 5.1e-50 169.5 0.1 9.2e-50 168.7 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM61816.1 - 2.3e-12 46.8 0.0 1.8e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM61816.1 - 0.0011 18.6 0.0 0.0035 16.9 0.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain An_peroxidase PF03098.15 KFM61817.1 - 8.6e-188 625.2 0.0 1e-187 625.0 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase zf-met PF12874.7 KFM61821.1 - 4.7e-06 26.8 0.2 6.4e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM61821.1 - 5.6e-06 26.5 0.1 7.9e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KFM61821.1 - 0.0074 16.0 0.5 0.0086 15.8 0.5 1.1 1 0 0 1 1 1 1 U1 zinc finger zf-SCNM1 PF15803.5 KFM61821.1 - 0.079 12.6 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 PRIMA1 PF16101.5 KFM61822.1 - 2.1e-06 27.7 0.1 4.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 TMEM154 PF15102.6 KFM61822.1 - 0.0053 16.7 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 KFM61822.1 - 0.066 14.1 0.0 0.11 13.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 KFM61822.1 - 0.12 12.0 0.2 0.21 11.2 0.2 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family RIFIN PF02009.16 KFM61822.1 - 0.22 11.4 0.2 0.3 10.9 0.2 1.1 1 0 0 1 1 1 0 Rifin fn3 PF00041.21 KFM61823.1 - 2.8e-16 59.6 0.0 2.3e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM61823.1 - 0.00094 19.7 0.3 0.013 16.1 0.4 2.3 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain DUF3827 PF12877.7 KFM61823.1 - 0.16 10.3 0.1 0.26 9.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) I-set PF07679.16 KFM61824.1 - 0.00012 22.1 0.1 0.00015 21.7 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM61824.1 - 0.013 15.6 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFM61824.1 - 0.023 15.3 0.1 0.041 14.5 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain fn3 PF00041.21 KFM61824.1 - 0.035 14.5 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 Fibronectin type III domain TPR_1 PF00515.28 KFM61828.1 - 1.3e-43 145.1 24.5 2.7e-07 30.1 0.1 9.1 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 KFM61828.1 - 1e-38 128.3 22.1 0.00012 22.0 0.1 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 KFM61828.1 - 1.3e-37 124.9 31.3 6.1e-07 29.1 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat DUF1736 PF08409.11 KFM61828.1 - 4.9e-32 109.8 2.1 1e-31 108.7 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.6 KFM61828.1 - 5e-31 106.1 18.6 3.4e-07 29.8 0.0 8.3 4 2 5 9 9 9 6 TPR repeat TPR_16 PF13432.6 KFM61828.1 - 3.1e-28 98.1 18.8 2.5e-10 40.8 0.0 5.9 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM61828.1 - 6.1e-27 93.7 30.2 1.4e-09 38.1 0.1 7.1 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFM61828.1 - 2e-25 87.3 19.1 0.0024 18.1 0.2 10.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFM61828.1 - 3.2e-22 77.7 33.1 0.0014 18.4 0.1 9.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFM61828.1 - 2.8e-21 73.9 19.8 3.2e-05 23.7 0.0 8.2 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFM61828.1 - 1.4e-17 62.8 19.2 0.0051 17.5 0.0 8.6 3 3 6 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM61828.1 - 1.6e-17 63.8 14.0 0.00012 22.5 0.0 4.9 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_4 PF07721.14 KFM61828.1 - 6.3e-15 54.2 2.5 0.13 13.0 0.1 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM61828.1 - 5.4e-12 45.7 7.4 1.4e-08 34.6 0.2 3.5 2 1 1 3 3 3 2 MalT-like TPR region ANAPC3 PF12895.7 KFM61828.1 - 9e-10 38.6 18.1 2.4e-07 30.9 0.7 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFM61828.1 - 1.1e-08 35.1 8.9 0.0045 17.1 0.8 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM61828.1 - 6.6e-08 32.7 13.1 0.005 17.4 0.0 6.4 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFM61828.1 - 1.2e-05 24.7 13.8 0.19 10.9 0.6 4.2 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 KFM61828.1 - 1.5e-05 24.9 6.6 0.079 13.0 0.3 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat PPR PF01535.20 KFM61828.1 - 0.00027 21.0 7.8 1.2 9.5 0.1 5.2 6 0 0 6 6 3 2 PPR repeat DUF3856 PF12968.7 KFM61828.1 - 0.0015 18.6 4.3 1.8 8.6 0.1 4.6 3 1 2 5 5 4 1 Domain of Unknown Function (DUF3856) NARP1 PF12569.8 KFM61828.1 - 0.0022 17.0 9.7 0.21 10.5 0.6 3.2 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 KFM61828.1 - 0.013 15.2 12.0 0.052 13.2 0.0 4.6 1 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 KFM61828.1 - 0.023 15.0 7.1 18 5.7 0.0 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KFM61828.1 - 0.04 14.0 0.1 0.25 11.4 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 KFM61828.1 - 0.15 12.2 17.3 0.87 9.7 0.4 4.7 5 1 1 6 6 4 0 MIT (microtubule interacting and transport) domain Wzy_C_2 PF11846.8 KFM61828.1 - 0.23 11.4 10.3 2.6 7.9 0.1 4.7 4 2 1 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal Mad3_BUB1_I PF08311.12 KFM61828.1 - 0.26 11.3 12.7 0.54 10.3 2.9 4.8 5 1 0 5 5 5 0 Mad3/BUB1 homology region 1 BTAD PF03704.17 KFM61828.1 - 0.6 10.5 14.9 5.9 7.3 0.1 3.5 2 1 1 3 3 3 0 Bacterial transcriptional activator domain DUF5113 PF17140.4 KFM61828.1 - 2.2 8.0 7.0 3.7 7.3 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5113) TctB PF07331.11 KFM61828.1 - 8.7 6.6 9.8 2.1 8.6 1.7 2.6 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Hum_adeno_E3A PF05393.11 KFM61829.1 - 0.05 13.6 1.6 0.052 13.5 1.6 1.0 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Transposase_1 PF01359.18 KFM61830.1 - 5.8e-14 51.7 0.2 6.9e-14 51.4 0.2 1.1 1 0 0 1 1 1 1 Transposase (partial DDE domain) HMG_box PF00505.19 KFM61831.1 - 3.2e-16 59.5 0.9 7.4e-16 58.3 0.9 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM61831.1 - 7.7e-11 42.4 1.2 3.3e-10 40.4 1.2 2.1 1 0 0 1 1 1 1 HMG-box domain SYF2 PF08231.12 KFM61831.1 - 1.4 9.3 12.8 0.6 10.5 1.3 2.9 2 1 0 2 2 2 0 SYF2 splicing factor Carn_acyltransf PF00755.20 KFM61832.1 - 5.2e-140 467.9 0.1 5.8e-140 467.7 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3128 PF11326.8 KFM61832.1 - 0.026 14.9 0.7 0.16 12.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) Carn_acyltransf PF00755.20 KFM61833.1 - 2.8e-08 32.9 0.3 3.4e-08 32.6 0.3 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RVT_1 PF00078.27 KFM61834.1 - 8.7e-45 152.9 0.0 1.6e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM61834.1 - 1.7e-20 73.0 1.5 1e-19 70.5 0.2 2.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KFM61834.1 - 1.3e-11 44.9 0.0 3.4e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 KFM61834.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.6 KFM61834.1 - 2.8 7.8 12.2 1.5 8.6 1.3 3.3 3 0 0 3 3 3 0 Zinc knuckle DUF4371 PF14291.6 KFM61835.1 - 1e-09 38.4 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) CRISPR_Cas2 PF09827.9 KFM61835.1 - 0.039 14.1 1.7 0.95 9.7 0.0 3.0 4 0 0 4 4 4 0 CRISPR associated protein Cas2 DDE_Tnp_1_7 PF13843.6 KFM61836.1 - 0.0033 16.8 0.1 0.0047 16.3 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 Pex14_N PF04695.13 KFM61836.1 - 0.11 13.2 0.6 0.16 12.7 0.1 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-CCHC PF00098.23 KFM61837.1 - 0.00021 21.2 2.9 0.00021 21.2 2.9 4.3 5 0 0 5 5 5 1 Zinc knuckle zf-CCHC_2 PF13696.6 KFM61837.1 - 4.6 7.2 9.8 2.1 8.3 3.7 2.5 2 0 0 2 2 2 0 Zinc knuckle BTB_2 PF02214.22 KFM61839.1 - 2.8e-30 104.5 0.0 4.6e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFM61839.1 - 0.0034 17.5 0.0 0.012 15.6 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 KFM61840.1 - 1.5e-34 119.4 9.6 1.7e-34 119.2 9.6 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFM61840.1 - 2.4e-13 49.9 5.7 5.5e-13 48.7 5.7 1.7 1 1 0 1 1 1 1 Ion channel DUF1616 PF07760.11 KFM61840.1 - 0.083 12.3 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) PKD_channel PF08016.12 KFM61840.1 - 0.095 11.4 4.3 0.11 11.1 4.3 1.1 1 0 0 1 1 1 0 Polycystin cation channel Pheromone PF08015.11 KFM61841.1 - 1.3 10.1 8.1 5.3 8.2 0.6 2.2 2 0 0 2 2 2 0 Fungal mating-type pheromone Ras PF00071.22 KFM61842.1 - 1.8e-32 112.1 0.0 2e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM61842.1 - 4.1e-10 39.9 0.0 6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM61842.1 - 0.0037 16.7 0.0 0.0044 16.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DDE_1 PF03184.19 KFM61843.1 - 4.3e-50 169.8 0.1 8e-50 168.9 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM61843.1 - 2.1e-12 46.9 0.0 1.7e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain ASL_C PF08328.11 KFM61844.1 - 0.0025 17.9 2.8 0.0029 17.7 0.8 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal AKNA PF12443.8 KFM61844.1 - 0.033 14.8 0.1 0.093 13.4 0.1 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor Spore_III_AB PF09548.10 KFM61844.1 - 0.42 10.7 4.3 1.1 9.4 2.0 2.8 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Nsp1_C PF05064.13 KFM61844.1 - 0.86 9.4 9.6 0.086 12.6 0.5 3.4 4 0 0 4 4 4 0 Nsp1-like C-terminal region HIP1_clath_bdg PF16515.5 KFM61844.1 - 2 9.1 7.0 0.68 10.6 2.4 2.6 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Peptidase_S10 PF00450.22 KFM61846.1 - 1.4e-94 317.9 2.8 1.7e-94 317.6 2.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KFM61846.1 - 0.15 11.3 0.0 1.4 8.2 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 eIF2A PF08662.11 KFM61847.1 - 0.0015 18.4 0.0 0.018 14.9 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KFM61847.1 - 0.0096 16.8 5.3 30 5.7 0.4 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF1699 PF08004.11 KFM61847.1 - 0.038 13.7 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) AFOR_C PF01314.18 KFM61847.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Peptidase_S10 PF00450.22 KFM61848.1 - 1e-96 324.9 0.2 1.2e-96 324.7 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KFM61848.1 - 0.0046 16.3 0.0 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Glyco_hydro_18 PF00704.28 KFM61851.1 - 2.9e-68 230.9 1.8 3.5e-68 230.6 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ADAM_CR PF08516.12 KFM61852.1 - 1.6e-23 83.3 8.3 1.6e-23 83.3 8.3 3.7 3 2 0 3 3 3 1 ADAM cysteine-rich Disintegrin PF00200.23 KFM61852.1 - 8.2e-20 71.4 28.4 8.2e-20 71.4 28.4 4.2 4 0 0 4 4 4 1 Disintegrin EGF_2 PF07974.13 KFM61852.1 - 1.3e-05 25.5 6.1 1.3e-05 25.5 6.1 5.7 4 1 1 5 5 5 1 EGF-like domain XRCC1_N PF01834.16 KFM61852.1 - 0.097 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 XRCC1 N terminal domain Syndecan PF01034.20 KFM61852.1 - 0.67 9.9 2.0 1.3 9.0 2.0 1.4 1 0 0 1 1 1 0 Syndecan domain TMF_TATA_bd PF12325.8 KFM61853.1 - 2e-27 95.7 15.9 2e-27 95.7 15.9 9.1 4 1 4 9 9 9 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KFM61853.1 - 1.2e-15 57.3 24.0 1.2e-15 57.3 24.0 9.9 6 2 3 9 9 9 4 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 KFM61853.1 - 0.0034 17.6 21.5 0.0034 17.6 21.5 7.8 4 1 3 8 8 8 2 Tropomyosin like PilW PF16074.5 KFM61853.1 - 0.078 13.0 1.4 0.19 11.7 0.2 2.3 2 0 0 2 2 2 0 Type IV Pilus-assembly protein W Big_2 PF02368.18 KFM61855.1 - 0.0043 16.9 2.1 2.8 7.9 0.0 3.9 4 0 0 4 4 4 2 Bacterial Ig-like domain (group 2) T2SS-T3SS_pil_N PF13629.6 KFM61855.1 - 0.039 13.7 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Pilus formation protein N terminal region PHP_C PF13263.6 KFM61855.1 - 0.08 12.7 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 PHP-associated Toluene_X PF03349.16 KFM61857.1 - 0.15 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) Trypsin PF00089.26 KFM61859.1 - 1.4e-54 185.3 0.0 1.7e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin CLIP_1 PF18322.1 KFM61859.1 - 1.6e-12 47.3 5.9 2.4e-12 46.7 4.7 2.0 2 0 0 2 2 2 1 Serine protease Clip domain PPAF-2 Trypsin_2 PF13365.6 KFM61859.1 - 0.00039 21.3 0.0 0.00071 20.5 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM61859.1 - 0.0045 17.4 0.0 0.009 16.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 KFM61859.1 - 0.065 12.8 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 Trypsin PF00089.26 KFM61860.1 - 3e-32 112.2 0.3 3.4e-32 112.0 0.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KFM61862.1 - 2.1e-33 116.0 0.0 2.9e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin Exo_endo_phos PF03372.23 KFM61864.1 - 0.067 12.7 0.0 0.082 12.4 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Homeodomain PF00046.29 KFM61865.1 - 2.1e-09 37.1 2.1 4.4e-09 36.0 2.1 1.5 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 KFM61867.1 - 1.4e-33 116.4 0.0 2.4e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM61867.1 - 2.8e-29 102.2 0.0 4.7e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFM61867.1 - 2e-05 25.6 16.2 2e-05 25.6 16.2 2.0 2 1 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFM61867.1 - 0.0024 16.7 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFM61867.1 - 0.04 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFM61867.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4371 PF14291.6 KFM61868.1 - 1.4e-21 77.3 0.0 2.8e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF1759 PF03564.15 KFM61869.1 - 5.6e-35 120.5 1.3 5.3e-32 110.8 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1759) gag-asp_proteas PF13975.6 KFM61869.1 - 2.7e-05 24.6 0.0 5.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 KFM61869.1 - 5.1e-05 23.1 0.9 7.4e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 KFM61869.1 - 7.6e-05 23.3 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.8 KFM61869.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon peptidase THAP PF05485.12 KFM61871.1 - 6.1e-15 55.9 0.6 6.1e-15 55.9 0.6 2.3 2 1 0 2 2 2 1 THAP domain RVT_1 PF00078.27 KFM61872.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 KFM61873.1 - 2.1e-47 161.1 1.3 4.6e-47 160.0 1.3 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 KFM61873.1 - 7.9e-06 25.5 0.1 1.7e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPRTase PF14681.6 KFM61873.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DDE_Tnp_1_7 PF13843.6 KFM61874.1 - 0.0064 15.8 0.1 0.0069 15.7 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 RT_RNaseH_2 PF17919.1 KFM61875.1 - 5.9e-61 202.7 0.1 1.9e-28 98.4 0.0 3.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM61875.1 - 9.7e-58 193.0 2.3 9.2e-28 96.6 0.2 4.1 4 0 0 4 4 3 2 RNase H-like domain found in reverse transcriptase Peptidase_A17 PF05380.13 KFM61875.1 - 6.4e-57 192.1 0.3 1.1e-54 184.9 0.1 3.4 3 0 0 3 3 3 1 Pao retrotransposon peptidase DUF5641 PF18701.1 KFM61875.1 - 5.4e-49 164.3 4.5 1.2e-27 95.9 2.8 3.0 2 0 0 2 2 2 2 Family of unknown function (DUF5641) DUF1759 PF03564.15 KFM61875.1 - 3e-37 127.8 1.1 3e-37 127.8 1.1 2.5 2 0 0 2 2 1 1 Protein of unknown function (DUF1759) Integrase_H2C2 PF17921.1 KFM61875.1 - 1.7e-25 88.9 4.6 7.4e-14 51.6 0.0 3.1 2 0 0 2 2 2 2 Integrase zinc binding domain DUF1758 PF05585.12 KFM61875.1 - 2.7e-23 82.5 0.1 1.7e-22 79.9 0.0 2.4 2 0 0 2 2 2 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 KFM61875.1 - 3.6e-22 79.0 9.5 2.9e-11 43.3 0.1 5.6 5 1 0 5 5 5 3 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM61875.1 - 3.4e-09 36.9 0.1 1.3e-06 28.6 0.0 3.2 3 0 0 3 3 3 1 Integrase core domain Asp_protease_2 PF13650.6 KFM61875.1 - 5e-08 33.5 0.0 5.6e-05 23.7 0.0 3.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM61875.1 - 6.8e-07 29.8 0.0 0.0092 16.5 0.0 3.3 3 0 0 3 3 2 2 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 KFM61875.1 - 1.3e-05 25.3 1.5 0.0013 18.9 0.0 3.0 2 0 0 2 2 2 1 H2C2 zinc finger RVP_2 PF08284.11 KFM61875.1 - 0.0013 18.5 0.1 0.026 14.3 0.1 2.7 2 0 0 2 2 2 1 Retroviral aspartyl protease KLRAQ PF10205.9 KFM61875.1 - 0.034 14.4 3.3 0.16 12.3 3.3 2.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF2730 PF10805.8 KFM61875.1 - 0.034 14.2 1.0 0.22 11.6 1.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3829 PF12889.7 KFM61875.1 - 0.094 12.2 9.0 0.1 12.0 2.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) RVP PF00077.20 KFM61875.1 - 0.11 12.8 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF5478 PF17572.2 KFM61877.1 - 0.073 13.2 0.4 0.098 12.8 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5478) His_Phos_1 PF00300.22 KFM61879.1 - 4.4e-17 62.4 0.0 1e-16 61.2 0.0 1.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DDE_Tnp_1_7 PF13843.6 KFM61880.1 - 3.6e-09 36.4 0.0 3.8e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 BCAS2 PF05700.11 KFM61881.1 - 1e-59 201.7 7.1 1.1e-59 201.6 7.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) EzrA PF06160.12 KFM61881.1 - 0.00036 18.9 3.9 0.0025 16.1 2.1 2.1 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Golgin_A5 PF09787.9 KFM61881.1 - 0.0016 17.9 3.9 0.0016 17.9 3.9 1.5 2 0 0 2 2 2 1 Golgin subfamily A member 5 Med9 PF07544.13 KFM61881.1 - 0.01 15.9 6.5 0.067 13.3 4.7 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CREPT PF16566.5 KFM61881.1 - 0.033 14.3 1.4 0.077 13.2 1.4 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Csm1_N PF18504.1 KFM61881.1 - 0.089 13.1 11.4 0.076 13.4 2.6 2.9 4 0 0 4 4 3 0 Csm1 N-terminal domain DUF5082 PF16888.5 KFM61881.1 - 0.11 12.7 7.1 0.069 13.4 4.6 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) Osmo_CC PF08946.10 KFM61881.1 - 0.25 11.6 0.4 0.25 11.6 0.4 2.4 3 0 0 3 3 3 0 Osmosensory transporter coiled coil PspA_IM30 PF04012.12 KFM61881.1 - 0.41 10.2 8.2 1.8 8.1 0.3 2.5 2 1 1 3 3 3 0 PspA/IM30 family FlaC_arch PF05377.11 KFM61881.1 - 0.41 11.1 4.2 22 5.5 0.1 3.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) THOC7 PF05615.13 KFM61881.1 - 0.43 10.9 6.7 5.6 7.3 1.3 2.4 2 1 0 2 2 2 0 Tho complex subunit 7 GAIN_A PF18619.1 KFM61881.1 - 0.53 10.5 3.4 2.1 8.6 0.1 2.8 2 1 1 3 3 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Cep57_CLD PF14073.6 KFM61881.1 - 0.61 10.1 9.4 4.1 7.4 9.4 2.4 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 APG6_N PF17675.1 KFM61881.1 - 1.4 9.4 11.2 16 6.0 11.2 2.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF724 PF05266.14 KFM61881.1 - 1.8 8.4 7.3 1.8 8.4 4.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 KFM61881.1 - 1.8 9.5 8.2 1.8 9.5 4.6 2.4 2 2 0 2 2 2 0 cGMP-dependent protein kinase interacting domain VPS13_C PF16909.5 KFM61882.1 - 3.6e-55 186.5 0.2 4.5e-51 173.1 0.0 2.2 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Apt1 PF10351.9 KFM61882.1 - 0.00067 18.6 0.1 0.083 11.7 0.0 3.2 3 1 0 3 3 3 1 Golgi-body localisation protein domain ATG_C PF09333.11 KFM61882.1 - 0.0013 19.1 0.0 0.0038 17.6 0.0 1.7 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain CAP PF00188.26 KFM61883.1 - 1.2e-15 58.4 2.2 3.1e-15 57.1 2.2 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Crisp PF08562.10 KFM61883.1 - 6.9e-14 52.2 18.6 6.9e-14 52.2 18.6 1.8 2 0 0 2 2 2 1 Crisp DUF3377 PF11857.8 KFM61884.1 - 0.73 9.8 5.2 1 9.3 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) EutH PF04346.12 KFM61884.1 - 1.9 7.6 6.4 2.4 7.3 6.4 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH TMEM154 PF15102.6 KFM61884.1 - 7.8 6.4 6.1 10 6.0 6.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family HTH_Tnp_Tc5 PF03221.16 KFM61885.1 - 9.6e-12 44.8 0.4 1.9e-11 43.8 0.4 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KFM61885.1 - 1e-10 41.6 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM61885.1 - 0.013 15.3 0.0 0.036 13.8 0.0 1.7 1 1 0 1 1 1 0 DDE superfamily endonuclease DUF3372 PF11852.8 KFM61885.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) DUF1759 PF03564.15 KFM61886.1 - 2.5e-07 30.8 0.1 2.6e-07 30.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1759 PF03564.15 KFM61887.1 - 8e-36 123.2 1.2 2e-35 121.9 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF2120 PF09893.9 KFM61887.1 - 0.33 11.1 2.1 3.9 7.6 0.6 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Peptidase_M14 PF00246.24 KFM61888.1 - 1.2e-59 202.5 0.1 1.8e-59 202.0 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFM61888.1 - 3.4e-11 43.3 0.0 6.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFM61888.1 - 2.8e-05 24.0 0.0 5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KFM61888.1 - 0.0029 16.7 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.24 KFM61889.1 - 0.031 14.1 0.1 0.056 13.2 0.0 1.5 2 0 0 2 2 2 0 Zinc carboxypeptidase I-set PF07679.16 KFM61890.1 - 1e-21 76.7 0.0 1.8e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM61890.1 - 6.1e-21 74.8 0.1 2e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM61890.1 - 2.3e-14 53.5 0.0 2e-09 37.6 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM61890.1 - 7.2e-14 51.7 0.1 3.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM61890.1 - 9.9e-09 35.3 0.0 9.9e-06 25.7 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM61890.1 - 4.3e-05 23.8 0.1 0.0051 17.2 0.0 2.3 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM61890.1 - 0.0017 18.6 0.1 0.05 13.9 0.0 2.7 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFM61890.1 - 0.0048 17.1 0.0 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 KFM61890.1 - 0.006 16.6 0.0 0.099 12.7 0.0 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM61890.1 - 0.068 13.2 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain Synaptobrevin PF00957.21 KFM61895.1 - 2.8e-29 100.7 4.4 3.7e-29 100.3 4.4 1.1 1 0 0 1 1 1 1 Synaptobrevin Baculo_F PF12259.8 KFM61895.1 - 0.0032 16.1 0.0 0.0036 15.9 0.0 1.0 1 0 0 1 1 1 1 Baculovirus F protein MCU PF04678.13 KFM61895.1 - 0.0035 17.5 0.6 0.004 17.3 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter ATG16 PF08614.11 KFM61895.1 - 0.0069 16.6 2.9 0.0083 16.4 2.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ArsP_1 PF03773.13 KFM61895.1 - 0.013 14.7 1.1 0.017 14.3 1.1 1.1 1 0 0 1 1 1 0 Predicted permease DDE_Tnp_4 PF13359.6 KFM61895.1 - 0.019 14.6 0.3 0.11 12.2 0.2 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease CD34_antigen PF06365.12 KFM61895.1 - 0.024 14.2 0.2 0.033 13.8 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family SNARE PF05739.19 KFM61895.1 - 0.037 14.0 1.3 0.073 13.1 0.3 2.0 2 0 0 2 2 2 0 SNARE domain BLOC1_2 PF10046.9 KFM61895.1 - 0.093 13.0 0.7 0.12 12.6 0.7 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4337 PF14235.6 KFM61895.1 - 0.11 12.6 2.2 0.17 12.0 2.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) GCN5L1 PF06320.13 KFM61895.1 - 0.14 12.3 5.8 0.19 11.9 5.8 1.1 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Prominin PF05478.11 KFM61895.1 - 0.37 8.7 3.9 0.67 7.8 3.9 1.4 1 1 0 1 1 1 0 Prominin Orf78 PF06024.12 KFM61895.1 - 0.52 10.6 4.5 1.1 9.6 0.2 2.0 1 1 1 2 2 2 0 Orf78 (ac78) Ferlin_C PF16165.5 KFM61895.1 - 6.8 6.6 9.6 12 5.8 9.6 1.7 1 1 0 1 1 1 0 Ferlin C-terminus Sec6 PF06046.13 KFM61897.1 - 2.6e-110 369.5 21.3 1.1e-99 334.4 12.2 2.8 3 1 0 3 3 3 2 Exocyst complex component Sec6 DUF3920 PF13058.6 KFM61897.1 - 0.0013 18.9 2.7 0.0018 18.5 0.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3920) Sec5 PF15469.6 KFM61897.1 - 0.0074 16.1 6.7 0.0074 16.1 6.7 2.4 2 0 0 2 2 2 1 Exocyst complex component Sec5 NPV_P10 PF05531.12 KFM61897.1 - 0.021 15.2 2.8 0.057 13.9 1.5 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KFM61897.1 - 0.22 11.9 1.7 1.1 9.8 0.2 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SOAR PF16533.5 KFM61897.1 - 0.22 11.5 7.0 0.076 13.0 0.4 3.4 3 1 0 3 3 3 0 STIM1 Orai1-activating region Baculo_PEP_C PF04513.12 KFM61897.1 - 1.9 8.5 6.0 2.1 8.4 0.8 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CREPT PF16566.5 KFM61897.1 - 4.5 7.4 9.5 0.41 10.8 2.6 2.9 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Mob_synth_C PF06463.13 KFM61898.1 - 6.2e-40 136.1 0.1 1.1e-39 135.3 0.1 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KFM61898.1 - 1.7e-30 106.6 0.0 2.5e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KFM61898.1 - 1.3e-09 38.4 0.1 8.5e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KFM61898.1 - 4.9e-05 23.4 0.0 0.00016 21.8 0.0 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain CBM_19 PF03427.13 KFM61898.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) GTP_EFTU PF00009.27 KFM61899.1 - 7.1e-44 149.7 0.0 1.1e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFM61899.1 - 2.9e-32 111.3 2.8 4.2e-32 110.8 0.1 2.7 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFM61899.1 - 1.8e-07 31.4 1.8 2.4e-07 31.0 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM61899.1 - 0.00094 19.2 0.0 0.0046 17.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.15 KFM61899.1 - 0.0057 16.3 0.6 0.0057 16.3 0.6 1.8 2 0 0 2 2 2 1 Ataxin-2 C-terminal region LPD34 PF18852.1 KFM61899.1 - 0.047 13.3 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 G-alpha PF00503.20 KFM61899.1 - 0.054 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit LUC7 PF03194.15 KFM61900.1 - 2.4e-97 325.5 11.3 2.4e-97 325.5 11.3 2.7 1 1 1 2 2 2 1 LUC7 N_terminus ATP12 PF07542.11 KFM61901.1 - 6.6e-26 90.9 0.0 7.6e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 ATP12 chaperone protein DUF116 PF01976.17 KFM61901.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF116 Myosin_tail_1 PF01576.19 KFM61902.1 - 0 1322.8 326.5 0 1322.5 326.5 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 KFM61902.1 - 1.1e-262 873.2 0.1 1.1e-262 873.2 0.1 3.3 3 1 0 3 3 3 1 Myosin head (motor domain) IQ PF00612.27 KFM61902.1 - 0.0047 16.6 0.7 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.6 KFM61902.1 - 0.028 14.7 0.0 0.028 14.7 0.0 7.4 5 2 3 9 9 9 0 AAA domain ACPS PF01648.20 KFM61903.1 - 1.4e-17 63.9 0.1 1.8e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily RRM_1 PF00076.22 KFM61904.1 - 2.7e-13 49.5 0.0 4.2e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KFM61904.1 - 1.5e-10 41.5 4.4 1.5e-10 41.5 4.4 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 DUF3972 PF13118.6 KFM61906.1 - 0.38 11.2 8.2 0.03 14.7 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Dynactin_p62 PF05502.13 KFM61907.1 - 3.3e-37 128.4 16.4 7.3e-20 71.2 9.2 2.1 2 0 0 2 2 2 2 Dynactin p62 family zinc_ribbon_12 PF11331.8 KFM61907.1 - 6.5 6.6 21.8 3.3 7.6 5.4 4.0 4 0 0 4 4 4 0 Probable zinc-ribbon domain S-AdoMet_synt_C PF02773.16 KFM61908.1 - 3.5e-68 227.9 0.1 2.5e-67 225.1 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFM61908.1 - 8.5e-44 148.7 0.0 2e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFM61908.1 - 2.7e-40 137.0 1.1 2.7e-40 137.0 1.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Tmemb_cc2 PF10267.9 KFM61909.1 - 6.4e-72 242.9 2.2 1e-71 242.2 2.2 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein SIR2_2 PF13289.6 KFM61909.1 - 0.037 14.1 0.0 0.088 12.9 0.0 1.6 1 0 0 1 1 1 0 SIR2-like domain TcdA_TcdB PF12919.7 KFM61909.1 - 0.043 13.1 1.9 0.06 12.6 1.9 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Fib_alpha PF08702.10 KFM61909.1 - 0.046 13.9 5.5 0.1 12.8 5.5 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3231 PF11553.8 KFM61909.1 - 0.095 12.3 0.6 0.15 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) LemA PF04011.12 KFM61909.1 - 0.46 10.3 5.1 0.89 9.4 5.1 1.4 1 0 0 1 1 1 0 LemA family Cdh1_DBD_1 PF18196.1 KFM61909.1 - 0.5 10.7 6.3 2.2 8.6 6.2 2.0 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Tmemb_cc2 PF10267.9 KFM61910.1 - 3.6e-59 200.9 9.1 4e-59 200.8 9.1 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Lebercilin PF15619.6 KFM61910.1 - 0.011 15.4 4.0 0.015 14.9 4.0 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF763 PF05559.11 KFM61910.1 - 0.018 14.3 0.6 0.021 14.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF2678 PF10856.8 KFM61910.1 - 0.041 13.8 0.9 0.057 13.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) SnoaL_4 PF13577.6 KFM61910.1 - 0.07 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DCB PF16213.5 KFM61910.1 - 0.073 12.7 2.9 0.11 12.2 2.9 1.4 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Exonuc_VII_L PF02601.15 KFM61910.1 - 0.087 12.4 1.0 0.088 12.4 1.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.12 KFM61910.1 - 0.11 12.5 2.0 0.15 12.1 2.0 1.2 1 0 0 1 1 1 0 Laminin Domain II XhlA PF10779.9 KFM61910.1 - 0.19 12.0 2.8 0.99 9.7 0.2 2.4 1 1 1 2 2 2 0 Haemolysin XhlA Baculo_p24 PF05073.12 KFM61910.1 - 0.61 9.8 4.2 0.89 9.3 4.0 1.4 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Amastin PF07344.11 KFM61910.1 - 5.2 6.9 8.2 6.6 6.6 5.4 1.9 1 1 1 2 2 2 0 Amastin surface glycoprotein SMAP PF15477.6 KFM61911.1 - 4.2e-18 66.1 7.9 4.9e-18 65.9 1.2 3.4 3 0 0 3 3 3 1 Small acidic protein family Gp_dh_C PF02800.20 KFM61912.1 - 5.1e-51 172.4 0.4 7.2e-51 171.9 0.4 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFM61912.1 - 7.1e-05 23.1 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Homeodomain PF00046.29 KFM61913.1 - 1.3e-24 85.8 6.3 2.4e-24 84.9 6.3 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFM61913.1 - 0.009 15.8 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFM61913.1 - 0.03 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain PIF1 PF05970.14 KFM61915.1 - 4.5e-28 98.5 0.0 6.1e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Phage_GPO PF05929.11 KFM61917.1 - 0.45 10.1 0.1 0.45 10.1 0.1 2.6 2 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase TruB_N PF01509.18 KFM61917.1 - 0.54 10.6 3.4 0.74 10.2 0.6 2.1 2 0 0 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) DUF1459 PF07312.11 KFM61923.1 - 0.5 10.6 9.7 0.58 10.4 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) Ribosomal_S30 PF04758.14 KFM61924.1 - 2e-30 104.7 12.0 2.8e-30 104.3 12.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.23 KFM61924.1 - 3.6e-07 29.8 0.0 5.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFM61924.1 - 0.041 13.7 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like N6-adenineMlase PF10237.9 KFM61925.1 - 3.1e-46 157.1 0.6 4.7e-46 156.5 0.6 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 KFM61925.1 - 0.00074 19.2 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 AD PF09793.9 KFM61925.1 - 0.18 12.0 0.5 0.37 11.0 0.1 1.7 2 0 0 2 2 2 0 Anticodon-binding domain MPC PF03650.13 KFM61926.1 - 1.3e-39 134.8 0.3 1.4e-39 134.6 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MASE5 PF17178.4 KFM61926.1 - 0.047 13.5 0.2 0.049 13.5 0.2 1.1 1 0 0 1 1 1 0 Membrane-associated sensor DUF5360 PF17314.2 KFM61926.1 - 0.065 13.3 0.8 0.076 13.1 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5360) Fur_reg_FbpB PF13040.6 KFM61927.1 - 0.061 12.9 0.1 0.18 11.4 0.1 1.9 1 0 0 1 1 1 0 Fur-regulated basic protein B SbcD_C PF12320.8 KFM61927.1 - 0.091 13.1 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Sulfotransfer_3 PF13469.6 KFM61928.1 - 0.017 15.5 0.3 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM61928.1 - 0.036 13.5 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain DIL PF01843.19 KFM61928.1 - 0.044 14.1 0.1 0.06 13.6 0.1 1.2 1 0 0 1 1 1 0 DIL domain Ig_3 PF13927.6 KFM61931.1 - 2.3e-11 44.1 0.0 7.9e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFM61931.1 - 1.4e-10 41.4 4.0 1.2e-09 38.4 0.3 2.5 3 0 0 3 3 3 1 Fibronectin type III domain I-set PF07679.16 KFM61931.1 - 5.3e-10 39.2 0.0 1.4e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM61931.1 - 1.5e-07 31.7 0.0 3.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM61931.1 - 1.1e-06 28.7 0.0 2.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain PsbL PF02419.17 KFM61931.1 - 0.0081 16.1 1.4 0.017 15.1 1.4 1.5 1 0 0 1 1 1 1 PsbL protein Smoothelin PF12510.8 KFM61931.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein IP_trans PF02121.18 KFM61932.1 - 7.2e-115 382.8 0.1 1.1e-114 382.1 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DDHD PF02862.17 KFM61933.1 - 1.8e-40 139.5 3.1 7e-27 95.0 1.2 3.0 2 1 1 3 3 3 2 DDHD domain LNS2 PF08235.13 KFM61933.1 - 0.0049 16.4 0.0 0.5 9.8 0.0 2.2 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Acid_phosphat_B PF03767.14 KFM61933.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) G-patch PF01585.23 KFM61934.1 - 8.7e-09 35.1 0.8 1.5e-08 34.4 0.8 1.4 1 0 0 1 1 1 1 G-patch domain Misat_Tub_SegII PF10644.9 KFM61934.1 - 0.22 11.9 2.8 8.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain ZU5 PF00791.20 KFM61936.1 - 0.0011 19.2 0.1 0.0017 18.6 0.1 1.3 1 0 0 1 1 1 1 ZU5 domain BTB PF00651.31 KFM61939.1 - 2.4e-31 108.2 0.4 7.7e-31 106.6 0.2 1.9 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 KFM61939.1 - 1.1e-06 28.8 0.2 2.5e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 MATH domain BACK PF07707.15 KFM61939.1 - 0.0026 17.8 0.1 0.53 10.4 0.0 2.7 1 1 0 2 2 2 1 BTB And C-terminal Kelch BTB_2 PF02214.22 KFM61939.1 - 0.01 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Retrotran_gag_2 PF14223.6 KFM61940.1 - 3.7e-23 81.7 0.0 5.3e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TMCO5 PF14992.6 KFM61941.1 - 0.12 11.9 0.6 0.099 12.2 0.6 1.0 1 0 0 1 1 1 0 TMCO5 family Utp14 PF04615.13 KFM61942.1 - 7.7e-133 444.7 49.7 8e-75 252.9 39.8 2.0 1 1 1 2 2 2 2 Utp14 protein DUF1759 PF03564.15 KFM61943.1 - 0.0001 22.2 0.0 0.00012 22.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) SCF PF02404.15 KFM61943.1 - 0.046 13.1 0.2 0.046 13.1 0.2 1.0 1 0 0 1 1 1 0 Stem cell factor CNTF PF01110.17 KFM61943.1 - 0.15 11.4 0.1 0.16 11.3 0.1 1.0 1 0 0 1 1 1 0 Ciliary neurotrophic factor Integrin_alpha2 PF08441.12 KFM61944.1 - 9.7e-39 133.5 1.4 1.2e-38 133.3 1.4 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFM61944.1 - 5.5e-20 71.2 22.5 6.2e-10 39.0 0.4 5.8 6 0 0 6 6 6 4 FG-GAP repeat VCBS PF13517.6 KFM61944.1 - 3.6e-08 33.9 5.9 3.5e-05 24.3 1.8 4.0 1 1 3 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 KFM61944.1 - 2.8e-05 24.3 19.7 0.0096 16.1 0.1 6.7 7 0 0 7 7 7 2 FG-GAP repeat Destabilase PF05497.12 KFM61945.1 - 1.4e-38 131.8 11.3 1.7e-38 131.5 11.3 1.1 1 0 0 1 1 1 1 Destabilase Cast PF10174.9 KFM61946.1 - 7.9e-26 90.5 76.8 3.3e-23 81.9 43.3 7.1 1 1 5 7 7 7 4 RIM-binding protein of the cytomatrix active zone CENP-F_leu_zip PF10473.9 KFM61946.1 - 9.3e-13 48.4 352.9 5.6e-05 23.2 20.8 15.9 1 1 12 14 14 14 8 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFM61946.1 - 1.1e-09 37.6 333.7 0.0097 14.8 19.4 12.8 1 1 11 12 12 12 9 Spc7 kinetochore protein Fez1 PF06818.15 KFM61946.1 - 1.4e-05 25.7 316.8 0.01 16.3 32.6 11.2 1 1 8 9 9 9 5 Fez1 ERM PF00769.19 KFM61946.1 - 0.00034 20.5 381.5 0.0044 16.9 30.9 10.8 1 1 8 9 9 9 4 Ezrin/radixin/moesin family APG6_N PF17675.1 KFM61946.1 - 0.00077 20.0 386.5 0.04 14.4 23.6 17.1 1 1 15 17 17 17 9 Apg6 coiled-coil region HMMR_N PF15905.5 KFM61946.1 - 0.0042 16.6 20.3 0.0042 16.6 20.3 11.3 1 1 9 11 11 11 3 Hyaluronan mediated motility receptor N-terminal Lebercilin PF15619.6 KFM61946.1 - 0.0047 16.6 9.2 0.0047 16.6 9.2 13.7 1 1 10 13 13 13 6 Ciliary protein causing Leber congenital amaurosis disease KELK PF15796.5 KFM61946.1 - 0.011 16.1 15.8 0.011 16.1 15.8 19.6 6 5 17 23 23 23 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Golgin_A5 PF09787.9 KFM61946.1 - 1.7 8.0 340.1 0.092 12.2 53.4 12.8 1 1 12 13 13 13 0 Golgin subfamily A member 5 WD40 PF00400.32 KFM61948.1 - 2.7e-15 56.5 2.9 0.0012 19.6 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM61948.1 - 1.9e-06 28.1 4.8 0.0012 19.1 0.5 4.4 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Exo_endo_phos PF03372.23 KFM61949.1 - 4e-23 82.1 0.0 6.7e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thioredoxin_7 PF13899.6 KFM61949.1 - 0.085 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like EB PF01683.18 KFM61951.1 - 4.9e-05 23.5 5.1 4.9e-05 23.5 5.1 2.8 2 1 1 3 3 3 2 EB module EGF_3 PF12947.7 KFM61951.1 - 0.013 15.7 4.7 0.013 15.7 4.7 3.3 2 2 0 2 2 2 0 EGF domain FYVE PF01363.21 KFM61952.1 - 2.4e-21 75.6 7.9 2.4e-21 75.6 7.9 3.7 4 1 0 4 4 4 1 FYVE zinc finger NGP1NT PF08153.12 KFM61952.1 - 0.013 15.7 0.1 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 NGP1NT (NUC091) domain FYVE_2 PF02318.16 KFM61952.1 - 0.47 10.7 15.0 0.049 13.8 6.2 2.8 2 0 0 2 2 2 0 FYVE-type zinc finger F-box PF00646.33 KFM61955.1 - 2.4e-08 33.7 0.7 7.2e-08 32.1 0.2 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFM61955.1 - 3.3e-05 23.7 0.0 7.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KFM61955.1 - 0.00075 19.4 0.1 0.002 18.0 0.1 1.9 2 1 0 2 2 2 1 F-box CwsA PF10814.8 KFM61955.1 - 0.061 13.5 0.3 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA F-box PF00646.33 KFM61956.1 - 9e-09 35.0 1.1 2.9e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFM61956.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like ADIP PF11559.8 KFM61956.1 - 0.19 11.8 15.3 0.51 10.4 3.0 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Synaptobrevin PF00957.21 KFM61956.1 - 5.8 6.8 7.3 1 9.2 1.5 2.5 2 0 0 2 2 2 0 Synaptobrevin MCM_OB PF17207.3 KFM61957.1 - 1.6e-36 124.9 0.6 2.4e-36 124.3 0.6 1.2 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KFM61957.1 - 3.7e-16 59.6 0.2 5.9e-16 59.0 0.2 1.3 1 0 0 1 1 1 1 MCM N-terminal domain MCM PF00493.23 KFM61958.1 - 1.1e-89 299.4 0.2 1.8e-89 298.7 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KFM61958.1 - 1.3e-28 99.2 0.4 4.8e-28 97.4 0.4 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 KFM61958.1 - 4.6e-28 97.6 2.3 4.6e-28 97.6 2.3 1.9 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 KFM61958.1 - 3.6e-08 33.1 0.0 1.8e-07 30.8 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFM61958.1 - 8.6e-05 22.4 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM61958.1 - 0.00011 22.3 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFM61958.1 - 0.00065 19.4 0.1 0.0019 17.9 0.1 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain HABP4_PAI-RBP1 PF04774.15 KFM61958.1 - 0.011 16.6 1.1 0.029 15.2 1.1 1.7 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Mg_chelatase_C PF13335.6 KFM61958.1 - 0.094 13.4 0.2 0.46 11.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal NTPase_1 PF03266.15 KFM61958.1 - 0.16 11.9 1.0 0.9 9.4 0.3 2.5 2 1 0 3 3 3 0 NTPase LRR_4 PF12799.7 KFM61959.1 - 2.4e-18 65.9 23.4 1.3e-09 38.1 2.9 3.4 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM61959.1 - 1.7e-16 60.2 0.6 2.4e-16 59.7 0.6 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KFM61959.1 - 1.1e-08 34.7 10.9 2.6e-08 33.5 3.2 3.2 2 2 1 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 KFM61959.1 - 4.2e-06 26.4 10.8 0.0086 16.1 0.1 4.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KFM61959.1 - 0.00066 19.9 14.4 1.6 9.6 0.1 5.0 5 1 0 5 5 5 2 Leucine Rich Repeat BUD22 PF09073.10 KFM61959.1 - 0.005 16.2 31.1 0.006 16.0 31.1 1.1 1 0 0 1 1 1 1 BUD22 LRR_5 PF13306.6 KFM61959.1 - 0.044 13.8 0.1 0.065 13.2 0.1 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_2 PF07723.13 KFM61959.1 - 0.19 12.5 4.1 21 6.0 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat Nop14 PF04147.12 KFM61959.1 - 7.5 4.6 44.7 10 4.2 44.7 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KFM61959.1 - 8.1 5.8 46.7 9.9 5.5 46.7 1.2 1 0 0 1 1 1 0 SDA1 Ank_2 PF12796.7 KFM61961.1 - 6.9e-23 81.1 5.1 4.1e-14 52.9 0.3 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM61961.1 - 2.5e-15 56.6 8.2 2.4e-09 37.5 0.1 4.4 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM61961.1 - 1.4e-14 54.0 9.5 2e-07 31.1 0.0 5.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM61961.1 - 1.5e-12 46.5 7.1 0.0053 17.2 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KFM61961.1 - 2e-08 34.3 10.0 9.3e-05 22.7 0.1 4.7 5 0 0 5 5 5 2 Ankyrin repeat DUF4568 PF15132.6 KFM61961.1 - 0.00045 19.7 0.1 0.00088 18.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4568) RNA_POL_M_15KD PF02150.16 KFM61962.1 - 3.3e-05 23.6 4.1 3.3e-05 23.6 4.1 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KFM61962.1 - 4.2e-05 23.4 6.5 0.0063 16.5 0.1 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain TFIIS_C PF01096.18 KFM61962.1 - 0.00058 19.7 0.6 0.00058 19.7 0.6 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.6 KFM61962.1 - 0.00067 19.0 5.9 0.064 12.7 0.1 2.9 3 0 0 3 3 3 2 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFM61962.1 - 0.0044 17.1 6.0 0.57 10.4 0.1 3.0 3 0 0 3 3 3 1 Zinc ribbon domain IBR PF01485.21 KFM61962.1 - 0.027 14.7 4.0 0.33 11.2 1.1 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Rubredoxin PF00301.20 KFM61962.1 - 0.04 14.0 4.0 1.3 9.2 0.0 3.0 3 0 0 3 3 3 0 Rubredoxin ADK_lid PF05191.14 KFM61962.1 - 0.043 13.8 4.9 1.3 9.1 0.1 2.8 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-ISL3 PF14690.6 KFM61962.1 - 0.11 13.1 4.3 1.4 9.7 0.1 3.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.6 KFM61962.1 - 0.16 11.8 0.3 0.16 11.8 0.3 3.0 3 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 KFM61962.1 - 0.28 11.2 4.2 0.092 12.8 0.6 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 KFM61962.1 - 0.39 10.7 3.6 2 8.4 0.1 2.3 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 KFM61962.1 - 0.4 10.7 8.3 16 5.6 8.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-FPG_IleRS PF06827.14 KFM61962.1 - 1.6 8.6 0.1 1.6 8.6 0.1 2.7 3 0 0 3 3 2 0 Zinc finger found in FPG and IleRS zf-ACC PF17848.1 KFM61962.1 - 3.4 7.8 8.4 8.3 6.6 0.0 2.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DpnI PF06044.12 KFM61962.1 - 3.5 7.2 6.3 1.8 8.2 1.4 2.0 1 1 1 2 2 2 0 Dam-replacing family zf-C4_Topoisom PF01396.19 KFM61962.1 - 3.6 7.5 10.0 3.1 7.7 1.0 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Nudix_N_2 PF14803.6 KFM61962.1 - 4.2 7.4 11.0 11 6.0 0.3 3.2 2 1 0 2 2 2 0 Nudix N-terminal PhnA_Zn_Ribbon PF08274.12 KFM61962.1 - 4.7 7.2 10.1 4.4 7.3 0.4 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 KFM61962.1 - 5 7.1 9.9 4.7 7.2 0.5 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 KFM61962.1 - 7.7 6.1 8.9 5.1 6.7 0.6 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger Lamp PF01299.17 KFM61963.1 - 7e-15 55.2 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFM61963.1 - 1.6e-05 24.8 0.0 4.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Neur_chan_memb PF02932.16 KFM61963.1 - 2.1 8.4 4.8 3.8 7.5 4.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sulfatase PF00884.23 KFM61964.1 - 2.1e-63 214.6 0.0 2.4e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFM61964.1 - 1.9e-05 24.5 0.1 0.00035 20.3 0.1 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFM61964.1 - 0.001 17.8 0.1 0.016 13.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) SEA PF01390.20 KFM61965.1 - 2e-06 27.8 0.2 2.6e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 SEA domain DUF5345 PF17280.2 KFM61965.1 - 0.031 14.2 0.0 0.076 13.0 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF3182 PF11379.8 KFM61965.1 - 0.064 12.2 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Trypsin PF00089.26 KFM61966.1 - 2.8e-22 79.6 0.1 4.8e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 Trypsin Fz PF01392.22 KFM61966.1 - 3.8e-20 72.6 6.0 3.8e-20 72.6 6.0 3.2 3 0 0 3 3 3 1 Fz domain Ldl_recept_a PF00057.18 KFM61966.1 - 9.4e-08 32.2 36.9 3.7e-07 30.2 10.6 3.8 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 KFM61966.1 - 9.1e-07 29.3 0.0 2.5e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Glyco_transf_34 PF05637.12 KFM61967.1 - 0.034 13.9 0.1 0.034 13.9 0.1 1.0 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family HtrL_YibB PF09612.10 KFM61967.1 - 0.044 13.3 1.0 0.053 13.0 1.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) ApoO PF09769.9 KFM61968.1 - 9.8e-18 64.4 0.0 1.7e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein O BRCT_assoc PF12820.7 KFM61968.1 - 0.0076 16.1 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Serine-rich domain associated with BRCT DUF659 PF04937.15 KFM61974.1 - 1e-06 28.7 1.0 0.012 15.5 0.5 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KFM61974.1 - 3.3e-06 26.8 0.0 8.9e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region OrsD PF12013.8 KFM61974.1 - 0.0098 16.3 0.1 0.029 14.8 0.1 1.8 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_12 PF18658.1 KFM61974.1 - 0.02 14.4 0.3 0.058 13.0 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-BED PF02892.15 KFM61974.1 - 0.057 13.5 3.9 0.12 12.4 3.9 1.6 1 0 0 1 1 1 0 BED zinc finger PriA_CRR PF18319.1 KFM61974.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2H2 PF00096.26 KFM61974.1 - 0.33 11.5 1.3 1 9.9 1.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM61974.1 - 0.4 11.6 1.9 0.77 10.8 0.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Propep_M14 PF02244.16 KFM61974.1 - 1.1 9.8 3.5 4.4 7.8 0.5 3.2 3 0 0 3 3 3 0 Carboxypeptidase activation peptide zf-H2C2_5 PF13909.6 KFM61974.1 - 3.8 7.4 5.1 2.6 7.9 2.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Secretogranin_V PF05281.11 KFM61975.1 - 1.7e-13 50.8 0.0 2e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) Thyroglobulin_1 PF00086.18 KFM61978.1 - 6.4e-16 57.8 7.1 4.9e-09 35.7 2.2 2.3 1 1 1 2 2 2 2 Thyroglobulin type-1 repeat Arc_C PF18162.1 KFM61980.1 - 1.1e-05 25.2 0.5 2.7e-05 23.9 0.5 1.6 1 0 0 1 1 1 1 Arc C-lobe DUF4726 PF15855.5 KFM61980.1 - 0.01 16.0 0.8 0.01 16.0 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4726) DUF4665 PF15679.5 KFM61980.1 - 4.8 7.9 11.0 15 6.3 7.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) Thyroglobulin_1 PF00086.18 KFM61982.1 - 6e-14 51.5 13.4 1e-13 50.8 5.7 2.1 1 1 1 2 2 2 2 Thyroglobulin type-1 repeat Pox_TAP PF03355.14 KFM61982.1 - 0.079 12.5 0.0 0.092 12.3 0.0 1.1 1 0 0 1 1 1 0 Viral Trans-Activator Protein Toxin_34 PF08396.10 KFM61982.1 - 1.8 9.4 14.0 3.1 8.6 3.2 2.5 1 1 1 2 2 2 0 Spider toxin omega agatoxin/Tx1 family Reprolysin_3 PF13582.6 KFM61983.1 - 6.7e-18 65.4 0.0 1.3e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 KFM61983.1 - 4.6e-12 46.3 7.8 4.6e-12 46.3 7.8 2.2 2 1 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin PF01421.19 KFM61983.1 - 3.1e-10 40.3 0.0 6e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 KFM61983.1 - 6.5e-09 36.0 0.1 1.1e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM61983.1 - 1.4e-07 31.8 0.0 4.3e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFM61983.1 - 1.4e-06 28.1 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFM61983.1 - 0.031 14.1 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Matrixin Pep_M12B_propep PF01562.19 KFM61984.1 - 0.00035 20.8 0.1 0.0032 17.7 0.0 2.2 2 0 0 2 2 2 1 Reprolysin family propeptide Dpy19 PF10034.9 KFM61985.1 - 1e-54 185.9 2.3 1.2e-54 185.7 2.3 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Dpy19 PF10034.9 KFM61986.1 - 3e-20 72.0 14.4 3.1e-20 72.0 14.4 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Dpy19 PF10034.9 KFM61987.1 - 1.4e-20 73.1 0.2 1.5e-20 73.0 0.2 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation ERAP1_C PF11838.8 KFM61987.1 - 0.0023 17.5 0.1 0.0024 17.5 0.1 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Dpy19 PF10034.9 KFM61988.1 - 5e-81 272.8 0.1 5.5e-81 272.7 0.1 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Pcc1 PF09341.10 KFM61989.1 - 3.1e-17 62.5 0.1 3.5e-17 62.3 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Phosphodiest PF01663.22 KFM61990.1 - 9.8e-15 55.0 1.1 7.4e-12 45.5 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFM61990.1 - 1e-06 28.3 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFM61990.1 - 3.8e-06 26.5 0.1 0.00034 20.1 0.0 2.2 2 0 0 2 2 2 2 Sulfatase RWD PF05773.22 KFM61994.1 - 8.3e-08 32.5 7.4 2e-06 28.1 0.2 2.7 2 1 0 2 2 2 2 RWD domain zf-rbx1 PF12678.7 KFM61994.1 - 0.00041 20.6 6.0 0.0013 18.9 6.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM61994.1 - 0.00047 20.0 7.5 0.0022 17.8 7.5 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM61994.1 - 0.00095 19.5 6.3 0.0075 16.6 6.2 2.7 1 1 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KFM61994.1 - 0.0035 17.4 1.4 0.01 15.9 1.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 KFM61994.1 - 0.005 17.1 1.2 0.005 17.1 1.2 2.9 2 0 0 2 2 2 1 RING-like domain zf-RING_5 PF14634.6 KFM61994.1 - 0.14 12.1 9.5 0.2 11.6 7.5 2.5 2 1 0 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 KFM61994.1 - 0.39 10.9 3.7 4.3 7.6 3.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 KFM61994.1 - 1 9.4 7.5 1.8 8.7 6.0 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFM61994.1 - 2.4 8.1 8.0 13 5.8 8.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM61994.1 - 2.5 8.0 10.6 0.078 12.8 2.6 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Dus PF01207.17 KFM61995.1 - 5e-55 186.8 0.0 7.4e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 KFM61995.1 - 0.004 17.0 1.2 0.004 17.0 1.2 3.3 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFM61995.1 - 0.41 11.4 9.8 0.076 13.7 5.8 1.9 1 1 0 1 1 1 0 Torus domain Tnp_zf-ribbon_2 PF13842.6 KFM61996.1 - 5.8e-05 23.8 11.3 0.00018 22.2 11.3 1.7 1 1 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.16 KFM61996.1 - 0.2 12.0 5.6 0.3 11.4 5.6 1.4 1 1 0 1 1 1 0 C1 domain DDE_Tnp_1_7 PF13843.6 KFM61997.1 - 6.8e-17 61.8 0.1 7.7e-17 61.6 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF5521 PF17659.1 KFM61999.1 - 1.5e-06 26.4 0.0 1.9e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5521) DUF5521 PF17659.1 KFM62000.1 - 0.0055 14.6 0.0 0.006 14.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5521) DUF4539 PF15072.6 KFM62000.1 - 0.033 14.2 0.0 0.048 13.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4539) DUF5521 PF17659.1 KFM62001.1 - 4.5e-12 44.7 0.0 5.2e-12 44.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5521) BRCA-2_OB1 PF09103.10 KFM62001.1 - 0.00068 19.6 0.0 0.00096 19.1 0.0 1.2 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Helitron_like_N PF14214.6 KFM62002.1 - 2.5e-12 47.4 0.0 2.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4443 PF14544.6 KFM62002.1 - 0.03 14.6 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) zf-C2H2_4 PF13894.6 KFM62004.1 - 1.2e-25 88.0 104.0 0.0022 18.7 0.3 17.1 17 0 0 17 17 17 11 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM62004.1 - 1.3e-19 69.4 111.1 0.0019 18.5 0.1 17.1 17 0 0 17 17 17 9 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KFM62004.1 - 5.2e-06 26.1 0.5 5.2e-06 26.1 0.5 9.7 12 0 0 12 12 11 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFM62004.1 - 2.1e-05 24.8 80.3 0.015 15.6 11.0 10.2 5 4 4 9 9 9 5 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFM62004.1 - 0.00033 20.8 79.3 0.28 11.5 0.0 13.1 15 0 0 15 15 14 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM62004.1 - 0.00041 20.7 65.6 0.011 16.1 0.1 11.8 13 0 0 13 13 13 5 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFM62004.1 - 0.0016 18.8 0.1 0.0016 18.8 0.1 16.4 19 2 0 19 19 19 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFM62004.1 - 0.027 14.5 0.3 0.027 14.5 0.3 10.3 11 0 0 11 11 10 0 C2H2-type zinc finger YniB PF14002.6 KFM62004.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 YniB-like protein Mycoplasma_p37 PF06646.11 KFM62004.1 - 0.18 11.0 1.3 0.4 9.9 1.3 1.5 1 0 0 1 1 1 0 High affinity transport system protein p37 zf-WRNIP1_ubi PF18279.1 KFM62004.1 - 0.48 11.2 6.3 18 6.3 0.0 4.7 4 0 0 4 4 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Ca_hom_mod PF14798.6 KFM62005.1 - 9.1e-53 178.9 13.5 2.7e-35 121.7 4.4 2.0 1 1 1 2 2 2 2 Calcium homeostasis modulator DUF4446 PF14584.6 KFM62005.1 - 0.018 15.0 0.2 0.029 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) OS-D PF03392.13 KFM62005.1 - 0.028 14.5 0.2 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D MFS_1 PF07690.16 KFM62005.1 - 0.037 13.0 2.6 0.35 9.7 0.3 2.2 2 0 0 2 2 2 0 Major Facilitator Superfamily DUF1218 PF06749.12 KFM62005.1 - 7.6 7.1 7.6 7 7.2 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Glyco_hydro_31 PF01055.26 KFM62006.1 - 3.4e-27 95.7 0.0 4.5e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Raffinose_syn PF05691.12 KFM62007.1 - 0.023 12.5 0.0 0.025 12.4 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 DZF PF07528.14 KFM62009.1 - 2.1e-73 247.0 0.0 3.4e-73 246.3 0.0 1.3 1 0 0 1 1 1 1 DZF domain zf-met PF12874.7 KFM62009.1 - 1.8e-21 75.8 16.2 9e-07 29.1 1.7 4.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM62009.1 - 8.5e-15 54.6 13.7 0.00015 21.9 1.2 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM62009.1 - 0.0015 18.8 18.5 0.14 12.5 0.6 4.3 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM62009.1 - 0.047 14.5 9.7 3.4 8.7 0.8 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Gas_vesicle PF00741.18 KFM62009.1 - 0.47 10.6 1.3 1.1 9.5 1.3 1.6 1 0 0 1 1 1 0 Gas vesicle protein zf-C2H2 PF00096.26 KFM62009.1 - 0.64 10.6 15.1 4.4 8.0 0.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-U1 PF06220.12 KFM62009.1 - 0.77 9.6 17.7 2.4 8.0 1.7 3.5 3 0 0 3 3 3 0 U1 zinc finger zf-DBF PF07535.12 KFM62009.1 - 3.2 7.9 18.9 7.2 6.8 3.4 3.6 3 0 0 3 3 3 0 DBF zinc finger SMC_N PF02463.19 KFM62010.1 - 2.1e-27 96.0 32.3 6e-26 91.2 32.1 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM62010.1 - 9.3e-06 25.7 2.6 2.3e-05 24.3 2.6 1.7 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system PhyH PF05721.13 KFM62010.1 - 1.2 9.4 5.2 11 6.2 2.4 3.0 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Arm-DNA-bind_2 PF12167.8 KFM62010.1 - 2.4 8.1 6.3 1.4 8.9 0.8 2.8 2 0 0 2 2 2 0 Arm DNA-binding domain Fez1 PF06818.15 KFM62010.1 - 8.4 6.8 61.7 0.035 14.6 21.5 3.4 1 1 2 3 3 3 0 Fez1 Laminin_II PF06009.12 KFM62010.1 - 8.7 6.4 54.0 0.038 14.0 17.7 5.4 1 1 5 6 6 6 0 Laminin Domain II SMC_hinge PF06470.13 KFM62011.1 - 3.1e-13 50.1 0.0 3.2e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Spc7 PF08317.11 KFM62012.1 - 3e-05 23.1 8.8 3e-05 23.1 8.8 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein DegS PF05384.11 KFM62012.1 - 0.0055 16.2 11.7 0.0071 15.8 3.6 2.6 1 1 2 3 3 3 1 Sensor protein DegS DUF948 PF06103.11 KFM62012.1 - 0.023 15.0 2.3 0.042 14.1 0.3 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) RNase_PH_C PF03725.15 KFM62012.1 - 0.038 14.0 1.1 0.1 12.6 1.1 1.8 1 1 0 1 1 1 0 3' exoribonuclease family, domain 2 Vac_Fusion PF02346.16 KFM62012.1 - 0.046 13.3 5.4 0.084 12.5 0.9 2.6 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 EzrA PF06160.12 KFM62012.1 - 0.048 11.8 18.0 0.056 11.6 18.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Phospholip_B PF04916.13 KFM62012.1 - 0.068 11.7 1.8 0.069 11.7 1.8 1.0 1 0 0 1 1 1 0 Phospholipase B APG6_N PF17675.1 KFM62012.1 - 0.083 13.4 17.4 0.053 14.1 15.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3573 PF12097.8 KFM62012.1 - 0.13 11.0 3.1 0.14 11.0 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3040 PF11239.8 KFM62012.1 - 0.14 12.4 0.8 0.23 11.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Macoilin PF09726.9 KFM62012.1 - 0.17 10.4 13.4 0.2 10.2 12.7 1.3 1 1 0 1 1 1 0 Macoilin family Cauli_AT PF03233.13 KFM62012.1 - 0.2 11.6 8.6 0.38 10.7 8.5 1.5 1 1 0 1 1 1 0 Aphid transmission protein TMF_TATA_bd PF12325.8 KFM62012.1 - 0.34 11.1 16.9 0.31 11.3 7.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Rx_N PF18052.1 KFM62012.1 - 0.35 11.2 5.6 0.2 12.0 1.5 2.5 1 1 2 3 3 3 0 Rx N-terminal domain ADIP PF11559.8 KFM62012.1 - 0.46 10.5 17.1 0.22 11.6 10.8 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YlqD PF11068.8 KFM62012.1 - 0.57 10.6 14.4 0.2 12.1 5.3 2.1 1 1 1 2 2 2 0 YlqD protein DUF4407 PF14362.6 KFM62012.1 - 0.64 9.3 4.0 0.81 9.0 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAP1_N PF04849.13 KFM62012.1 - 0.67 9.1 19.6 2.4 7.3 9.2 1.9 1 1 1 2 2 2 0 HAP1 N-terminal conserved region TMPIT PF07851.13 KFM62012.1 - 0.91 8.7 10.5 1.1 8.4 10.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF812 PF05667.11 KFM62012.1 - 0.96 8.3 18.8 0.55 9.1 4.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FliD_N PF02465.18 KFM62012.1 - 1.2 9.8 7.2 0.4 11.4 3.7 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus CENP-Q PF13094.6 KFM62012.1 - 1.8 8.7 14.6 0.21 11.8 9.5 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin-6_N PF09177.11 KFM62012.1 - 1.8 9.1 8.7 0.23 12.0 4.8 1.7 2 1 0 2 2 1 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 KFM62012.1 - 1.9 8.5 6.9 2.5 8.1 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 KFM62012.1 - 2 7.9 9.8 2.4 7.7 9.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 KFM62012.1 - 3.6 8.3 9.3 4.5 8.0 4.1 2.4 1 1 1 2 2 2 0 SlyX ZapB PF06005.12 KFM62012.1 - 3.9 8.0 21.4 0.51 10.8 11.5 2.4 1 1 1 2 2 2 0 Cell division protein ZapB ACCA PF03255.14 KFM62012.1 - 4.2 7.2 9.7 1 9.2 1.8 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CLZ PF16526.5 KFM62012.1 - 7.7 7.0 13.7 6.6 7.2 2.7 2.9 1 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF745 PF05335.13 KFM62012.1 - 8.5 6.1 10.6 6.4 6.5 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) SIR2 PF02146.17 KFM62013.1 - 1.3e-51 175.0 0.0 5.1e-51 173.1 0.0 1.8 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.16 KFM62013.1 - 0.014 14.3 0.1 0.026 13.5 0.0 1.4 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit Med27 PF11571.8 KFM62013.1 - 0.09 13.1 0.3 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 27 zn-ribbon_14 PF16503.5 KFM62013.1 - 0.12 11.9 0.5 0.12 11.9 0.5 1.8 2 0 0 2 2 2 0 Zinc-ribbon zinc_ribbon_5 PF13719.6 KFM62013.1 - 0.16 11.8 1.3 8.6 6.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFM62013.1 - 0.34 11.1 1.6 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain RecR PF02132.15 KFM62013.1 - 0.68 9.6 3.0 1.5 8.5 0.8 2.3 2 0 0 2 2 2 0 RecR protein Nucleoporin_N PF08801.11 KFM62014.1 - 1.9e-49 168.6 0.1 2.1e-49 168.5 0.1 1.0 1 0 0 1 1 1 1 Nup133 N terminal like Lactonase PF10282.9 KFM62014.1 - 0.00023 20.6 0.4 0.0005 19.4 0.1 1.6 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Utp8 PF10395.9 KFM62014.1 - 0.039 12.5 0.1 0.051 12.1 0.1 1.1 1 0 0 1 1 1 0 Utp8 family Nucleoporin_C PF03177.14 KFM62016.1 - 0.0038 16.0 0.1 0.0043 15.9 0.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal PRORP PF16953.5 KFM62016.1 - 0.036 13.6 0.0 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein-only RNase P DUF2700 PF10912.8 KFM62017.1 - 0.013 15.5 0.2 0.016 15.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) zf-B_box PF00643.24 KFM62018.1 - 1.4e-11 44.3 23.6 6.8e-09 35.7 10.0 5.1 5 0 0 5 5 5 2 B-box zinc finger zf-RING_5 PF14634.6 KFM62018.1 - 2.3e-05 24.3 7.6 2.3e-05 24.3 7.6 3.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM62018.1 - 0.00016 21.6 5.1 0.00016 21.6 5.1 3.1 4 0 0 4 4 4 1 RING-type zinc-finger PHD PF00628.29 KFM62018.1 - 0.0015 18.3 5.9 0.0015 18.3 5.9 5.4 4 1 1 5 5 5 1 PHD-finger RuBisCO_large PF00016.20 KFM62018.1 - 0.1 11.7 0.3 0.25 10.5 0.3 1.5 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Sema PF01403.19 KFM62019.1 - 2.7e-35 122.0 0.0 3.8e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFM62019.1 - 0.00016 22.2 2.9 0.00016 22.2 2.9 3.0 2 2 0 3 3 3 1 Plexin repeat Ig_3 PF13927.6 KFM62019.1 - 0.0022 18.6 0.0 0.0097 16.5 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM62019.1 - 0.0029 17.9 0.0 0.013 15.8 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM62019.1 - 0.042 13.9 0.0 0.22 11.6 0.0 2.2 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFM62019.1 - 0.048 13.8 0.0 1.3 9.3 0.0 2.5 1 1 0 1 1 1 0 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFM62019.1 - 0.056 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain PSP PF04046.16 KFM62020.1 - 7.2e-21 73.8 3.8 7.2e-21 73.8 3.8 2.0 2 0 0 2 2 2 1 PSP FKBP_N PF01346.18 KFM62020.1 - 0.013 16.4 4.6 0.58 11.2 2.1 2.3 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase CENP-B_dimeris PF09026.10 KFM62020.1 - 0.23 11.9 10.2 0.56 10.6 10.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tim54 PF11711.8 KFM62020.1 - 0.46 9.2 9.3 0.071 11.9 0.3 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF382 PF04037.13 KFM62021.1 - 8.6e-33 113.2 0.2 8.6e-33 113.2 0.2 5.7 4 1 1 5 5 5 1 Domain of unknown function (DUF382) SAP PF02037.27 KFM62021.1 - 1.2e-14 53.6 3.6 5.1e-13 48.4 0.6 3.0 2 0 0 2 2 2 2 SAP domain AA_permease_N PF08403.10 KFM62021.1 - 0.055 13.0 0.1 0.17 11.4 0.1 1.8 1 0 0 1 1 1 0 Amino acid permease N-terminal P66_CC PF16563.5 KFM62022.1 - 9.3e-08 31.6 9.3 3.7e-07 29.6 9.3 2.1 1 0 0 1 1 1 1 Coiled-coil and interaction region of P66A and P66B with MBD2 AT_hook PF02178.19 KFM62022.1 - 0.08 12.9 2.4 0.26 11.3 2.4 1.9 1 0 0 1 1 1 0 AT hook motif GATA PF00320.27 KFM62022.1 - 0.44 10.2 2.2 1.1 8.9 2.2 1.7 1 1 0 1 1 1 0 GATA zinc finger FMO-like PF00743.19 KFM62023.1 - 3.5e-156 520.7 0.1 4e-156 520.6 0.1 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM62023.1 - 9.5e-17 61.2 0.6 1.5e-11 44.2 0.2 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM62023.1 - 4.2e-12 45.9 0.0 2.5e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM62023.1 - 7.2e-11 41.8 1.0 3.9e-07 29.5 0.1 3.8 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFM62023.1 - 0.00012 22.2 0.1 0.00036 20.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFM62023.1 - 0.00051 20.5 1.1 0.097 13.2 0.3 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM62023.1 - 0.0021 17.3 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family AAA_assoc PF14363.6 KFM62023.1 - 0.0091 16.3 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Domain associated at C-terminal with AAA FAD_binding_2 PF00890.24 KFM62023.1 - 0.033 13.3 1.0 7.8 5.5 0.0 2.9 3 0 0 3 3 3 0 FAD binding domain Peptidase_M17_N PF02789.17 KFM62023.1 - 0.038 13.8 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DAO PF01266.24 KFM62023.1 - 0.1 12.2 0.0 17 4.9 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase FMO-like PF00743.19 KFM62024.1 - 4.6e-29 101.2 0.1 4.8e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like FMO-like PF00743.19 KFM62025.1 - 1e-44 152.9 0.2 1.2e-44 152.7 0.2 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFM62025.1 - 6.3e-06 25.6 0.0 7.9e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM62025.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFM62025.1 - 0.011 14.9 0.3 0.41 9.7 0.1 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAS PF03059.16 KFM62025.1 - 0.012 14.9 0.1 0.38 10.1 0.0 2.0 1 1 1 2 2 2 0 Nicotianamine synthase protein FAD_binding_2 PF00890.24 KFM62025.1 - 0.082 12.0 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KFM62025.1 - 0.14 12.1 0.1 1.9 8.4 0.1 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 KFM62025.1 - 0.18 11.3 0.0 4 6.9 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FMO-like PF00743.19 KFM62026.1 - 1.5e-164 548.3 0.0 1.7e-164 548.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM62026.1 - 9e-20 71.1 0.7 1.6e-13 50.6 0.3 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM62026.1 - 3.4e-13 49.5 0.0 4e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM62026.1 - 1e-12 47.9 2.1 1.1e-08 34.7 0.1 3.3 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFM62026.1 - 0.0018 18.5 0.0 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFM62026.1 - 0.019 15.5 1.5 1.6 9.4 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFM62026.1 - 0.031 14.3 0.1 36 4.3 0.0 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 KFM62026.1 - 0.04 13.5 0.8 4.4 6.8 0.0 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 KFM62026.1 - 0.089 12.0 0.2 0.84 8.8 0.0 2.1 2 0 0 2 2 2 0 Thi4 family DUF2358 PF10184.9 KFM62026.1 - 0.12 12.6 0.4 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) Peptidase_M17_N PF02789.17 KFM62026.1 - 0.22 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain HMG_box PF00505.19 KFM62029.1 - 4.1e-14 52.7 0.1 9.2e-14 51.6 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM62029.1 - 3.5e-06 27.5 0.1 9.2e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 HMG-box domain Kinesin PF00225.23 KFM62031.1 - 1.9e-47 161.8 1.3 1.9e-47 161.8 1.3 1.6 2 0 0 2 2 2 1 Kinesin motor domain HALZ PF02183.18 KFM62031.1 - 0.052 13.8 2.4 0.052 13.8 2.4 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper LRS4 PF10422.9 KFM62031.1 - 1.9 8.0 10.7 11 5.5 9.1 2.0 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 PCRF PF03462.18 KFM62031.1 - 5.4 6.8 7.6 0.54 10.1 2.5 1.8 2 0 0 2 2 2 0 PCRF domain Glyco_tranf_2_3 PF13641.6 KFM62032.1 - 0.047 13.6 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 T3SS_needle_F PF09392.10 KFM62032.1 - 0.22 11.7 7.8 1.2 9.3 0.9 3.9 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF AcylCoA_dehyd_C PF12186.8 KFM62032.1 - 1.2 9.3 6.9 0.41 10.8 0.7 3.3 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal Spc7 PF08317.11 KFM62032.1 - 2.5 6.9 57.3 0.29 10.0 5.6 4.1 1 1 3 4 4 4 0 Spc7 kinetochore protein LsmAD PF06741.13 KFM62032.1 - 4.5 7.9 6.5 1.7 9.2 0.3 3.5 2 1 1 3 3 3 0 LsmAD domain Pro_isomerase PF00160.21 KFM62034.1 - 1.4e-43 148.9 0.3 3.2e-43 147.7 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RecG_N PF17190.4 KFM62034.1 - 0.19 12.5 13.0 2.6 8.8 13.0 2.7 1 1 0 1 1 1 0 RecG N-terminal helical domain FRB_dom PF08771.11 KFM62034.1 - 1.3 9.5 6.5 1.2 9.6 2.3 2.6 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain DUF4407 PF14362.6 KFM62034.1 - 3.7 6.8 10.3 4.9 6.4 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FGF PF00167.18 KFM62037.1 - 0.0027 17.8 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 Fibroblast growth factor DHHC PF01529.20 KFM62038.1 - 4.8e-37 127.0 9.8 4.8e-37 127.0 9.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.7 KFM62038.1 - 0.0017 18.3 0.6 0.0041 17.1 0.6 1.7 1 1 0 1 1 1 1 Double zinc ribbon DUF957 PF06117.11 KFM62038.1 - 0.082 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) DUF1272 PF06906.11 KFM62038.1 - 0.77 9.9 8.0 0.41 10.8 4.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) DUF3671 PF12420.8 KFM62038.1 - 4.2 7.5 10.8 0.16 12.0 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function Complex1_49kDa PF00346.19 KFM62039.1 - 5e-126 419.3 0.0 6.2e-126 419.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KFM62039.1 - 0.027 13.4 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 Nickel-dependent hydrogenase HTH_Tnp_Tc5 PF03221.16 KFM62042.1 - 5.7e-09 35.9 0.2 1.2e-08 34.9 0.2 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain 7tm_1 PF00001.21 KFM62043.1 - 5.7e-13 48.8 1.6 5.7e-13 48.8 1.6 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM62043.1 - 3.1e-05 23.5 0.9 4.7e-05 22.9 0.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Ribosomal_L27A PF00828.19 KFM62044.1 - 1.8e-17 64.2 0.0 2e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Glyco_transf_8 PF01501.20 KFM62045.1 - 0.0002 21.0 0.1 0.0002 21.0 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 8 IU_nuc_hydro PF01156.19 KFM62047.1 - 2.1e-17 63.7 0.2 2.3e-17 63.6 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.19 KFM62048.1 - 1.3e-22 80.8 0.0 1.4e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Pkinase PF00069.25 KFM62049.1 - 3.7e-66 223.2 0.0 5.2e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM62049.1 - 2.7e-51 174.4 0.0 4e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM62049.1 - 1.5e-06 27.3 0.1 3.1e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase DUF1241 PF06840.11 KFM62049.1 - 0.0025 17.4 0.0 0.0076 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.6 KFM62049.1 - 0.0034 16.7 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM62049.1 - 0.042 12.8 0.4 0.76 8.7 0.4 2.2 1 1 0 1 1 1 0 Haspin like kinase domain Evf PF18270.1 KFM62049.1 - 0.069 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Virulence factor Evf 53-BP1_Tudor PF09038.10 KFM62050.1 - 0.046 13.7 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor DEAD PF00270.29 KFM62051.1 - 6.7e-46 156.3 0.4 1.2e-45 155.4 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM62051.1 - 2.7e-32 111.4 1.2 1.5e-31 109.0 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM62051.1 - 4.2e-07 30.1 0.0 7.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFM62051.1 - 0.0016 18.8 0.2 0.01 16.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFM62051.1 - 0.0026 17.5 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KFM62051.1 - 0.0042 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Helicase CMS1 PF14617.6 KFM62051.1 - 0.007 15.7 0.6 0.041 13.2 0.0 2.2 1 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KFM62051.1 - 0.057 13.4 0.3 0.31 11.0 0.1 2.4 1 1 1 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.6 KFM62051.1 - 0.063 13.6 2.4 0.11 12.8 0.6 2.3 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 KFM62051.1 - 0.074 12.5 0.5 6.9 6.0 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain tRNA-synt_1b PF00579.25 KFM62051.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) ArfGap PF01412.18 KFM62052.1 - 2.1e-33 114.9 0.5 2.1e-33 114.9 0.5 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ribosomal_L37ae PF01780.19 KFM62052.1 - 0.088 12.9 0.4 0.47 10.6 0.1 2.2 2 0 0 2 2 2 0 Ribosomal L37ae protein family MAM PF00629.23 KFM62053.1 - 1.6e-13 50.9 0.1 4.3e-13 49.5 0.1 1.6 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu FARP PF01581.16 KFM62054.1 - 0.00021 21.2 30.7 1.8 9.4 0.6 11.4 11 1 1 12 12 12 3 FMRFamide related peptide family DUF4154 PF13689.6 KFM62054.1 - 0.028 14.7 0.0 0.46 10.7 0.0 2.6 2 2 0 3 3 3 0 YfiR/HmsC-like tRNA_int_endo_N PF02778.14 KFM62054.1 - 0.77 9.5 4.2 36 4.1 0.0 4.5 4 1 0 4 4 4 0 tRNA intron endonuclease, N-terminal domain DDE_Tnp_1_7 PF13843.6 KFM62055.1 - 4.3e-88 296.0 1.2 4.9e-88 295.8 1.2 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM62055.1 - 0.00017 21.3 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain PWWP PF00855.17 KFM62056.1 - 6.7e-17 61.7 0.1 3.4e-16 59.4 0.0 2.3 2 0 0 2 2 2 1 PWWP domain Dimer_Tnp_hAT PF05699.14 KFM62059.1 - 0.08 12.7 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region FA_desaturase PF00487.24 KFM62060.1 - 7.9e-14 52.1 16.5 7.9e-14 52.1 16.5 1.7 1 1 1 2 2 2 1 Fatty acid desaturase wnt PF00110.19 KFM62061.1 - 1.1e-18 67.9 0.9 1.2e-18 67.8 0.9 1.0 1 0 0 1 1 1 1 wnt family NADH_u_ox_C PF12853.7 KFM62061.1 - 0.074 13.0 0.1 0.099 12.6 0.1 1.2 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF4920 PF16267.5 KFM62061.1 - 0.087 12.8 0.3 0.34 10.9 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4920) Peptidase_M1_N PF17900.1 KFM62062.1 - 7.7e-48 163.2 1.1 1e-47 162.7 1.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KFM62062.1 - 2.4e-19 69.8 0.1 5.4e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain Atg14 PF10186.9 KFM62063.1 - 0.0088 15.2 2.2 0.011 14.8 2.2 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ZZ PF00569.17 KFM62064.1 - 7.7e-12 44.8 11.7 1.2e-11 44.2 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_3 PF09069.11 KFM62064.1 - 5.6e-10 39.5 0.0 9.1e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 EF-hand C1_2 PF03107.16 KFM62064.1 - 1.5e-05 25.2 5.6 2.6e-05 24.5 5.6 1.4 1 0 0 1 1 1 1 C1 domain EF-hand_2 PF09068.11 KFM62065.1 - 6.1e-28 97.4 1.8 6.9e-28 97.3 1.8 1.0 1 0 0 1 1 1 1 EF hand ArsA_ATPase PF02374.15 KFM62065.1 - 0.093 11.9 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase EF-hand_14 PF17959.1 KFM62065.1 - 0.095 13.1 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain Swi6_N PF18530.1 KFM62065.1 - 0.17 12.0 1.5 2.2 8.4 0.2 2.2 1 1 1 2 2 2 0 Swi6 N-terminal domain DUF2776 PF10951.8 KFM62067.1 - 0.15 11.3 0.2 0.15 11.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) Izumo-Ig PF16706.5 KFM62070.1 - 0.0027 17.7 0.2 0.0046 17.0 0.2 1.4 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain NGF PF00243.18 KFM62070.1 - 0.045 14.0 0.2 0.066 13.5 0.2 1.3 1 0 0 1 1 1 0 Nerve growth factor family Sugar_tr PF00083.24 KFM62071.1 - 5.5e-25 88.1 11.6 7.9e-25 87.6 11.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM62071.1 - 5.5e-11 42.0 35.8 4.9e-06 25.7 16.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily THAP PF05485.12 KFM62072.1 - 4.1e-13 50.1 1.7 5.3e-13 49.7 1.7 1.1 1 0 0 1 1 1 1 THAP domain Tmemb_cc2 PF10267.9 KFM62073.1 - 4.7e-149 496.9 22.4 6e-149 496.6 22.4 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Rootletin PF15035.6 KFM62073.1 - 0.0028 17.7 22.5 0.004 17.2 16.6 3.2 1 1 2 3 3 3 1 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.12 KFM62073.1 - 0.0051 16.9 0.2 0.0051 16.9 0.2 3.4 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF713 PF05218.14 KFM62073.1 - 0.0059 16.4 5.4 0.0059 16.4 5.4 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF713) Exonuc_VII_L PF02601.15 KFM62073.1 - 0.0095 15.5 20.2 0.052 13.1 0.4 2.3 2 1 0 2 2 2 2 Exonuclease VII, large subunit TcdA_TcdB PF12919.7 KFM62073.1 - 0.01 15.2 4.5 0.01 15.2 4.5 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Fib_alpha PF08702.10 KFM62073.1 - 0.044 14.0 28.0 0.21 11.8 7.7 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KFM62073.1 - 0.086 11.7 32.4 0.095 11.6 16.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DsbG_N PF18257.1 KFM62073.1 - 0.14 12.3 4.1 0.14 12.3 1.6 2.3 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal HMMR_N PF15905.5 KFM62073.1 - 0.27 10.6 32.7 0.47 9.9 10.7 2.5 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 KFM62073.1 - 0.82 9.1 32.5 0.78 9.1 19.5 2.5 2 1 0 2 2 2 0 Golgin subfamily A member 5 Fzo_mitofusin PF04799.13 KFM62073.1 - 1 8.9 15.4 0.12 11.9 0.4 3.1 2 1 0 2 2 2 0 fzo-like conserved region DUF763 PF05559.11 KFM62073.1 - 1.2 8.2 9.2 0.33 10.1 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF763) DUF2461 PF09365.10 KFM62073.1 - 2.3 8.1 5.6 22 4.9 0.4 2.9 2 1 0 2 2 2 0 Conserved hypothetical protein (DUF2461) Prominin PF05478.11 KFM62073.1 - 2.4 6.0 16.8 1.2 7.0 0.5 2.4 2 1 0 2 2 2 0 Prominin HPPK PF01288.20 KFM62073.1 - 2.4 8.7 6.8 1.4 9.4 0.5 2.6 2 0 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) BCDHK_Adom3 PF10436.9 KFM62073.1 - 2.8 7.7 11.7 0.28 11.0 5.7 2.1 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Pannexin_like PF12534.8 KFM62073.1 - 3.3 6.7 6.6 0.76 8.8 0.5 2.3 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Atg14 PF10186.9 KFM62073.1 - 4.1 6.4 23.2 0.19 10.8 6.3 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DCB PF16213.5 KFM62073.1 - 6.3 6.4 14.5 0.16 11.6 6.6 2.3 2 1 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 DIRP PF06584.13 KFM62073.1 - 8.2 6.7 11.2 0.23 11.7 1.2 2.7 2 2 0 2 2 2 0 DIRP zf-met PF12874.7 KFM62074.1 - 1.1e-20 73.3 26.5 1.9e-06 28.1 1.3 5.9 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM62074.1 - 1.9e-17 63.1 25.1 0.00012 22.3 0.1 5.7 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM62074.1 - 8.5e-13 48.5 27.1 0.0028 18.0 1.7 5.6 4 1 0 5 5 5 5 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM62074.1 - 3.5e-08 33.6 22.5 0.098 13.5 0.0 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-DBF PF07535.12 KFM62074.1 - 4.1e-05 23.6 23.4 0.15 12.2 0.1 5.7 5 0 0 5 5 5 2 DBF zinc finger VATC PF18716.1 KFM62074.1 - 0.00025 20.8 24.1 0.87 9.5 0.1 5.6 5 0 0 5 5 5 4 Vms1-associating treble clef domain zf-C2H2 PF00096.26 KFM62074.1 - 0.00068 20.0 24.7 1.2 9.7 0.0 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type AKAP95 PF04988.12 KFM62074.1 - 0.0029 17.8 24.3 0.096 12.9 6.8 4.1 2 2 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) DUF5402 PF17393.2 KFM62074.1 - 0.22 11.5 1.2 8.7 6.3 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5402) zf-BED PF02892.15 KFM62074.1 - 2.6 8.1 19.1 9.9 6.3 0.1 5.8 6 0 0 6 6 6 0 BED zinc finger zf-C2HC_2 PF13913.6 KFM62074.1 - 3.9 7.5 8.4 4.9 7.2 0.2 3.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type GDP_Man_Dehyd PF16363.5 KFM62075.1 - 6.2e-35 121.2 0.0 6.8e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFM62075.1 - 7e-34 117.3 0.0 7.9e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM62075.1 - 7.6e-15 54.7 0.1 8.8e-15 54.4 0.1 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFM62075.1 - 1.1e-13 51.0 0.1 1.4e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFM62075.1 - 1.7e-08 33.9 0.0 2.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFM62075.1 - 1.9e-06 27.3 0.2 1.5e-05 24.3 0.2 1.9 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KFM62075.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KFM62075.1 - 1.5e-05 24.6 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KFM62075.1 - 8.6e-05 22.5 0.0 0.00044 20.2 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFM62075.1 - 0.012 15.1 0.1 0.021 14.4 0.1 1.3 1 1 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 KFM62075.1 - 0.014 15.6 0.1 0.032 14.5 0.1 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KFM62075.1 - 0.035 13.7 0.1 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4296 PF14129.6 KFM62075.1 - 0.094 13.3 0.4 0.44 11.2 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4296) adh_short_C2 PF13561.6 KFM62075.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Isochorismatase PF00857.20 KFM62075.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 2 0 0 2 2 2 0 Isochorismatase family fn3 PF00041.21 KFM62076.1 - 7.6e-20 71.1 0.3 3.8e-19 68.8 0.4 1.9 2 0 0 2 2 2 1 Fibronectin type III domain Ig_3 PF13927.6 KFM62076.1 - 7.5e-08 32.9 0.1 1.5e-06 28.7 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM62076.1 - 6.4e-07 29.4 0.1 2.8e-06 27.3 0.0 2.1 2 2 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM62076.1 - 0.0003 21.0 0.0 0.00062 20.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM62076.1 - 0.0012 18.9 0.0 0.013 15.6 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Tissue_fac PF01108.17 KFM62076.1 - 0.0034 17.2 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Tissue factor fn3_4 PF16794.5 KFM62076.1 - 0.021 14.8 0.1 0.12 12.3 0.1 2.1 1 1 0 1 1 1 0 Fibronectin-III type domain Pur_ac_phosph_N PF16656.5 KFM62076.1 - 0.03 14.9 1.0 0.071 13.7 1.0 1.6 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM62076.1 - 0.053 13.8 0.1 0.1 12.9 0.1 1.6 1 1 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III RVT_1 PF00078.27 KFM62077.1 - 2e-41 142.0 0.1 4e-41 141.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM62077.1 - 7.1e-21 74.3 2.7 7.1e-21 74.3 2.7 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KFM62077.1 - 8.8e-14 51.9 2.5 2.4e-13 50.5 2.5 1.8 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM62077.1 - 1.8e-08 34.2 0.5 4e-08 33.1 0.5 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Exo_endo_phos PF03372.23 KFM62077.1 - 0.00093 18.8 0.0 0.0028 17.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ig_3 PF13927.6 KFM62082.1 - 1.2e-12 48.2 0.0 1.8e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM62082.1 - 8.2e-12 45.0 0.0 1.2e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFM62082.1 - 2.2e-08 34.1 0.0 1.5e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM62082.1 - 0.00013 22.2 0.0 0.00076 19.8 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM62082.1 - 0.0006 20.0 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFM62082.1 - 0.044 13.8 0.0 0.22 11.6 0.0 2.1 2 1 0 2 2 2 0 C17orf99 Ig domain HAP2-GCS1 PF10699.9 KFM62087.1 - 5.3e-17 61.5 0.1 7.2e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 Male gamete fusion factor HTH_Tnp_Tc3_2 PF01498.18 KFM62088.1 - 4.2e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62088.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62088.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62088.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62088.1 - 0.025 14.7 0.4 0.085 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM62088.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Carn_acyltransf PF00755.20 KFM62091.1 - 6.7e-16 58.0 0.2 7.1e-16 58.0 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.20 KFM62092.1 - 3.3e-16 59.1 0.0 3.5e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Myosin_tail_1 PF01576.19 KFM62093.1 - 3.2e-13 48.5 40.7 3.2e-13 48.5 40.7 2.9 1 1 1 3 3 3 1 Myosin tail HIP1_clath_bdg PF16515.5 KFM62093.1 - 2.4e-05 24.9 66.3 0.071 13.7 14.6 6.3 5 1 1 6 6 6 3 Clathrin-binding domain of Huntingtin-interacting protein 1 FlxA PF14282.6 KFM62093.1 - 0.00017 21.5 7.9 0.00017 21.5 7.9 6.1 3 1 2 6 6 5 1 FlxA-like protein TolA_bind_tri PF16331.5 KFM62093.1 - 0.00046 20.2 54.0 0.0051 16.8 0.7 6.9 2 1 2 6 6 6 2 TolA binding protein trimerisation ADIP PF11559.8 KFM62093.1 - 0.00092 19.3 17.9 0.00092 19.3 17.9 5.8 2 2 5 7 7 6 2 Afadin- and alpha -actinin-Binding SKA2 PF16740.5 KFM62093.1 - 0.001 18.8 8.7 0.001 18.8 8.7 6.3 3 1 2 6 6 6 1 Spindle and kinetochore-associated protein 2 SlyX PF04102.12 KFM62093.1 - 0.0011 19.5 2.2 0.0011 19.5 2.2 7.4 4 1 3 7 7 6 1 SlyX DUF724 PF05266.14 KFM62093.1 - 0.0016 18.3 14.7 0.0016 18.3 14.7 4.7 2 2 1 5 5 5 1 Protein of unknown function (DUF724) AAA_13 PF13166.6 KFM62093.1 - 0.0024 16.6 25.1 0.0024 16.6 25.1 3.2 2 1 1 3 3 3 1 AAA domain Filament PF00038.21 KFM62093.1 - 0.0037 16.9 65.0 0.13 11.8 25.8 4.6 2 1 0 3 3 3 2 Intermediate filament protein CALCOCO1 PF07888.11 KFM62093.1 - 0.0054 15.7 15.3 0.0054 15.7 15.3 3.9 1 1 4 5 5 5 1 Calcium binding and coiled-coil domain (CALCOCO1) like Laminin_II PF06009.12 KFM62093.1 - 0.0099 15.9 8.7 0.0099 15.9 8.7 5.7 3 1 3 6 6 6 3 Laminin Domain II KASH_CCD PF14662.6 KFM62093.1 - 0.01 15.7 80.7 0.056 13.3 18.3 5.4 2 2 3 5 5 5 0 Coiled-coil region of CCDC155 or KASH BORCS7 PF16088.5 KFM62093.1 - 0.014 15.7 2.1 0.014 15.7 2.1 3.4 2 2 0 3 3 3 0 BLOC-1-related complex sub-unit 7 PRKG1_interact PF15898.5 KFM62093.1 - 0.015 16.2 16.3 0.015 16.2 16.3 5.9 3 2 3 6 6 6 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 KFM62093.1 - 0.024 13.5 76.5 0.018 13.9 18.7 4.4 3 1 2 5 5 5 0 Spc7 kinetochore protein Prp19 PF08606.11 KFM62093.1 - 0.032 14.2 1.3 0.032 14.2 1.3 5.3 4 2 2 6 6 5 0 Prp19/Pso4-like DUF3800 PF12686.7 KFM62093.1 - 0.041 14.5 0.3 2 9.0 0.3 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF5082 PF16888.5 KFM62093.1 - 0.05 13.9 1.3 0.05 13.9 1.3 5.5 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 KFM62093.1 - 0.069 13.7 89.3 0.23 12.0 25.4 6.0 2 2 4 6 6 6 0 Apg6 coiled-coil region Pox_A_type_inc PF04508.12 KFM62093.1 - 0.099 12.5 0.2 0.099 12.5 0.2 4.3 5 0 0 5 5 2 0 Viral A-type inclusion protein repeat GBR2_CC PF18455.1 KFM62093.1 - 0.33 11.1 10.5 6.3 7.0 0.2 4.9 5 0 0 5 5 4 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain ATG16 PF08614.11 KFM62093.1 - 0.57 10.4 79.8 0.079 13.2 18.1 5.0 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 KFM62093.1 - 1.7 8.7 24.3 2.5 8.2 5.1 3.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 KFM62093.1 - 1.9 8.3 65.6 0.86 9.4 15.9 3.4 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4201 PF13870.6 KFM62093.1 - 2.6 7.8 67.8 0.071 12.8 16.6 4.7 2 1 1 4 4 4 0 Domain of unknown function (DUF4201) Cas6b_C PF17262.2 KFM62093.1 - 4 7.6 9.9 3.2 7.9 0.4 3.2 2 1 1 3 3 3 0 Cas6b C-terminal domain FlaC_arch PF05377.11 KFM62093.1 - 6.7 7.2 43.6 1.4 9.4 0.8 8.2 5 2 4 9 9 9 0 Flagella accessory protein C (FlaC) HEAT PF02985.22 KFM62094.1 - 8.2e-13 47.4 4.3 0.082 13.2 0.2 7.8 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 KFM62094.1 - 1.1e-09 38.6 0.1 0.17 12.4 0.0 6.4 6 0 0 6 6 6 3 HEAT-like repeat Cnd1 PF12717.7 KFM62094.1 - 1.2e-06 28.6 2.0 0.04 13.9 0.0 4.7 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM62094.1 - 8.8e-06 26.0 0.1 0.17 12.3 0.0 5.1 5 1 1 6 6 6 2 HEAT repeats IFRD PF05004.13 KFM62094.1 - 2.6e-05 23.5 1.4 0.0033 16.6 0.0 3.9 3 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KFM62094.1 - 0.00024 21.0 1.4 1.9 8.6 0.1 5.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat UME PF08064.13 KFM62094.1 - 0.019 14.8 0.1 0.7 9.8 0.0 3.1 2 0 0 2 2 2 0 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 KFM62094.1 - 0.18 12.4 0.4 1.3e+02 3.3 0.0 4.8 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region 2OG-FeII_Oxy_2 PF13532.6 KFM62095.1 - 2.8e-17 63.5 0.0 7.1e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RE_NgoBV PF09564.10 KFM62095.1 - 0.011 15.2 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 0 NgoBV restriction endonuclease 2OG-FeII_Oxy_2 PF13532.6 KFM62096.1 - 1.3e-22 80.9 0.0 3.2e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RE_NgoBV PF09564.10 KFM62096.1 - 0.015 14.8 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 NgoBV restriction endonuclease zf_ZIC PF18366.1 KFM62097.1 - 2.8e-27 94.5 7.4 1.4e-26 92.3 1.6 3.1 3 0 0 3 3 3 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KFM62097.1 - 1.1e-07 31.9 6.5 8.9e-06 25.9 1.0 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM62097.1 - 1.3e-07 31.7 0.9 1.3e-07 31.7 0.9 4.4 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM62097.1 - 0.0051 17.5 0.8 0.0051 17.5 0.8 6.5 7 0 0 7 7 7 3 C2H2-type zinc finger KIF1B PF12423.8 KFM62097.1 - 0.8 10.2 3.4 0.8 10.2 0.3 2.5 3 0 0 3 3 3 0 Kinesin protein 1B SAM_KSR1 PF13543.6 KFM62098.1 - 4.1e-45 153.1 6.2 7.2e-45 152.3 6.2 1.4 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Pkinase_Tyr PF07714.17 KFM62098.1 - 1.2e-10 41.1 0.0 2.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFM62098.1 - 1e-08 34.9 9.0 1.9e-08 34.0 9.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 KFM62098.1 - 5.1e-08 32.6 0.0 9.3e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain zf-RING-like PF08746.11 KFM62098.1 - 0.00059 20.1 2.3 0.0014 18.9 2.3 1.6 1 0 0 1 1 1 1 RING-like domain C1_2 PF03107.16 KFM62098.1 - 0.00078 19.7 5.6 0.0018 18.6 5.6 1.6 1 0 0 1 1 1 1 C1 domain DNA_repr_REX1B PF14966.6 KFM62098.1 - 0.03 15.0 0.3 0.077 13.7 0.3 1.7 1 0 0 1 1 1 0 DNA repair REX1-B DUF4268 PF14088.6 KFM62098.1 - 0.13 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Pkinase_Tyr PF07714.17 KFM62099.1 - 2.4e-34 118.8 0.0 3e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM62099.1 - 5.4e-28 98.1 0.0 6.9e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFM62099.1 - 2e-06 27.4 0.0 2.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM62099.1 - 0.0089 15.4 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM62099.1 - 0.13 11.8 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 RIO1 family FYVE_2 PF02318.16 KFM62100.1 - 6.1e-27 94.2 3.4 1.1e-26 93.4 3.4 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger Ribosomal_S14 PF00253.21 KFM62100.1 - 0.077 12.8 0.3 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e UPF0167 PF03691.14 KFM62100.1 - 0.15 11.9 6.7 0.22 11.3 3.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) FYVE PF01363.21 KFM62100.1 - 0.15 12.2 11.3 0.28 11.3 10.7 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-piccolo PF05715.13 KFM62100.1 - 0.26 11.5 9.2 1.1 9.4 9.2 2.2 1 1 0 1 1 1 0 Piccolo Zn-finger Ephrin_rec_like PF07699.13 KFM62100.1 - 2.3 8.0 7.3 3 7.7 3.0 2.7 1 1 1 2 2 2 0 Putative ephrin-receptor like C1_1 PF00130.22 KFM62100.1 - 6.6 6.7 10.5 1.4 8.8 5.8 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Thioredoxin_8 PF13905.6 KFM62101.1 - 1.2e-07 32.0 0.0 1.4e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFM62101.1 - 0.081 13.4 0.0 0.089 13.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM62102.1 - 1.4e-07 31.7 0.0 2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFM62102.1 - 0.018 15.5 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain I_LWEQ PF01608.17 KFM62103.1 - 2.6e-51 173.9 14.0 2.6e-51 173.9 14.0 4.7 3 2 2 5 5 5 1 I/LWEQ domain ANTH PF07651.16 KFM62103.1 - 6.7e-26 90.9 0.1 6.7e-26 90.9 0.1 2.8 3 0 0 3 3 3 1 ANTH domain ATG16 PF08614.11 KFM62103.1 - 0.0026 18.0 56.7 0.0056 16.9 12.2 5.9 3 2 2 6 6 6 3 Autophagy protein 16 (ATG16) HALZ PF02183.18 KFM62103.1 - 0.5 10.6 14.0 0.62 10.3 1.2 4.8 4 1 0 4 4 4 0 Homeobox associated leucine zipper ANTH PF07651.16 KFM62104.1 - 1.9e-27 96.0 0.0 2e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 ANTH domain RT_RNaseH_2 PF17919.1 KFM62105.1 - 6.1e-31 106.4 0.0 1.4e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM62105.1 - 1.5e-27 95.9 0.0 3.3e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM62105.1 - 2.7e-18 66.3 0.1 6.8e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KFM62105.1 - 1.2e-14 54.2 0.1 2.3e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM62105.1 - 8.4e-07 29.2 0.0 2.2e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain DUF5526 PF17664.1 KFM62105.1 - 0.043 13.4 1.2 2.3 7.8 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5526) zf-H2C2 PF09337.10 KFM62105.1 - 0.12 12.6 0.1 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger Rad51 PF08423.11 KFM62106.1 - 6.8e-21 74.7 0.0 8.9e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KFM62106.1 - 6.3e-07 29.0 0.3 2.5e-06 27.0 0.3 2.1 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KFM62106.1 - 2.9e-05 23.7 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 KFM62106.1 - 0.00025 20.8 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFM62106.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Maelstrom PF13017.6 KFM62106.1 - 0.018 14.7 0.9 0.034 13.8 0.9 1.4 1 0 0 1 1 1 0 piRNA pathway germ-plasm component ABC_tran PF00005.27 KFM62106.1 - 0.027 15.0 0.0 0.045 14.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KFM62106.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PPV_E1_C PF00519.17 KFM62106.1 - 0.035 13.0 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase DnaB_C PF03796.15 KFM62106.1 - 0.035 13.4 0.0 0.055 12.8 0.0 1.5 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain ATP_bind_1 PF03029.17 KFM62106.1 - 0.035 13.9 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KFM62106.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 NACHT domain DUF647 PF04884.14 KFM62107.1 - 1.6e-43 149.1 0.5 1.7e-43 149.0 0.5 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis nsp7 PF08716.10 KFM62107.1 - 0.095 13.3 0.4 1.3 9.7 0.1 2.0 2 0 0 2 2 2 0 nsp7 replicase DUF647 PF04884.14 KFM62108.1 - 1.2e-05 25.0 0.2 2.2e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis HTH_48 PF17906.1 KFM62109.1 - 5.7e-15 55.2 0.3 6.9e-15 54.9 0.3 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase SpoVS PF04232.12 KFM62109.1 - 0.017 14.8 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) Torus PF16131.5 KFM62110.1 - 2.3e-05 25.0 0.2 3.4e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 KFM62110.1 - 4.4e-05 23.2 6.4 6.5e-05 22.6 6.4 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KFM62110.1 - 0.00032 20.5 4.1 0.00032 20.5 4.1 1.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM62110.1 - 0.00036 20.5 7.1 0.0006 19.8 7.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_3 PF15663.5 KFM62110.1 - 0.0018 18.5 0.3 0.003 17.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger containing family HECW_N PF16562.5 KFM62110.1 - 0.051 13.4 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 WW PF00397.26 KFM62111.1 - 0.024 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 WW domain dsrm PF00035.26 KFM62112.1 - 9e-14 51.9 0.0 1.1e-13 51.7 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif PEGA PF08308.11 KFM62112.1 - 0.12 12.3 0.2 2.4 8.1 0.0 2.1 1 1 1 2 2 2 0 PEGA domain DUF1241 PF06840.11 KFM62113.1 - 0.019 14.6 0.2 0.026 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) TMEM215 PF15746.5 KFM62113.1 - 0.035 13.6 1.6 0.042 13.3 1.6 1.2 1 1 0 1 1 1 0 TMEM215 family DUF961 PF06125.11 KFM62113.1 - 0.1 12.9 0.1 1.1 9.6 0.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF961) BST2 PF16716.5 KFM62115.1 - 0.019 15.6 15.4 0.44 11.2 5.3 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 SANTA PF09133.10 KFM62115.1 - 0.021 15.3 1.8 2.4 8.7 0.1 2.7 3 0 0 3 3 3 0 SANTA (SANT Associated) DUF1664 PF07889.12 KFM62115.1 - 0.17 11.9 10.7 0.088 12.9 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Aida_N PF08910.10 KFM62115.1 - 0.9 10.0 6.7 23 5.4 5.5 2.5 1 1 1 2 2 2 0 Aida N-terminus Prefoldin PF02996.17 KFM62115.1 - 2.3 8.1 12.7 0.61 10.0 3.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.15 KFM62115.1 - 7.8 6.3 9.7 4.1 7.2 2.3 2.5 1 1 0 2 2 2 0 Septum formation initiator Tnp_P_element PF12017.8 KFM62116.1 - 2.5e-15 56.5 0.1 4.7e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Transposase protein UCR_Fe-S_N PF10399.9 KFM62117.1 - 0.041 13.2 1.9 0.11 11.9 1.9 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DDE_1 PF03184.19 KFM62118.1 - 1.6e-26 93.0 0.5 2.1e-26 92.7 0.5 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease C2 PF00168.30 KFM62120.1 - 1.5e-39 134.5 0.0 1e-21 77.1 0.0 2.1 2 0 0 2 2 2 2 C2 domain Ribosomal_S5_C PF03719.15 KFM62123.1 - 8.7e-09 34.7 0.0 9.4e-09 34.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain CUB PF00431.20 KFM62124.1 - 4e-136 445.6 19.6 9.6e-27 93.5 0.1 7.1 7 0 0 7 7 7 7 CUB domain IL6Ra-bind PF09240.10 KFM62124.1 - 1.4 9.4 3.4 45 4.6 0.1 4.3 5 0 0 5 5 5 0 Interleukin-6 receptor alpha chain, binding CUB_2 PF02408.20 KFM62124.1 - 2.1 8.1 15.8 0.86 9.4 0.5 4.9 6 1 0 6 6 6 0 CUB-like domain MFS_1 PF07690.16 KFM62125.1 - 8.8e-07 28.2 17.7 1.2e-06 27.7 17.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM62125.1 - 4e-06 25.9 5.7 4e-06 25.9 5.7 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter HTH_Tnp_Tc3_2 PF01498.18 KFM62126.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62126.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62126.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62126.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62126.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62127.1 - 5e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62127.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62127.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62127.1 - 0.0027 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62127.1 - 2.2 9.0 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62128.1 - 2.6e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62128.1 - 1e-13 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62129.1 - 5.4e-16 58.6 2.2 5.4e-16 58.6 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM62129.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62129.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62129.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62129.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62131.1 - 4.1e-16 59.0 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62131.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62131.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62131.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62131.1 - 0.052 13.7 2.3 0.087 13.0 0.4 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM62131.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Zona_pellucida PF00100.23 KFM62132.1 - 1.3e-22 80.8 0.7 2.1e-22 80.1 0.7 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Pkinase PF00069.25 KFM62133.1 - 0.15 11.4 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 KFM62134.1 - 1.5e-13 50.7 0.0 1.7e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFM62134.1 - 5.6e-08 32.0 0.0 6.7e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFM62134.1 - 1.6e-07 30.9 0.0 1.8e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM62134.1 - 0.00014 21.3 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM62134.1 - 0.016 14.6 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like SWIB PF02201.18 KFM62134.1 - 0.072 13.0 0.7 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 SWIB/MDM2 domain Antimicrobial14 PF08109.11 KFM62134.1 - 0.14 12.2 1.3 0.43 10.7 1.1 1.9 2 0 0 2 2 2 0 Lactocin 705 family APH PF01636.23 KFM62134.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF772 PF05598.11 KFM62135.1 - 0.052 13.6 0.0 0.066 13.2 0.0 1.1 1 0 0 1 1 1 0 Transposase domain (DUF772) Dpy-30 PF05186.13 KFM62136.1 - 1.4e-18 66.3 0.4 1.9e-18 65.8 0.4 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 KFM62136.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit HTH_Tnp_Tc3_2 PF01498.18 KFM62137.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62137.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62137.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62137.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62137.1 - 1.9 9.2 15.6 0.12 13.0 1.9 3.3 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62138.1 - 9.5e-16 57.8 2.8 1.4e-15 57.3 1.6 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62138.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62138.1 - 2.2e-07 30.5 1.2 6.9e-07 28.9 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62138.1 - 0.0026 17.5 0.6 0.0074 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62138.1 - 0.028 14.6 0.4 0.089 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM62138.1 - 2.4 8.8 15.2 0.14 12.8 1.6 3.1 2 1 1 3 3 3 0 Homeodomain-like domain I-set PF07679.16 KFM62139.1 - 3.2e-05 23.9 0.0 3.2e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFM62139.1 - 0.00011 22.3 0.0 0.00011 22.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM62139.1 - 0.0063 17.1 0.0 0.0073 16.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM62139.1 - 0.0073 16.3 0.0 0.0073 16.3 0.0 1.1 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFM62139.1 - 0.021 14.4 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 KFM62139.1 - 0.04 14.3 0.0 0.04 14.3 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Herpes_gI PF01688.17 KFM62139.1 - 0.09 12.7 0.0 0.09 12.7 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I ig PF00047.25 KFM62139.1 - 0.13 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain DUF3762 PF12591.8 KFM62139.1 - 0.14 12.4 0.1 0.14 12.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3762) THAP PF05485.12 KFM62140.1 - 1.7e-12 48.1 1.7 1.7e-12 48.1 1.7 1.6 2 0 0 2 2 2 1 THAP domain HTH_Tnp_Tc3_2 PF01498.18 KFM62142.1 - 4.6e-16 58.8 0.9 8.6e-16 57.9 0.9 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM62142.1 - 8.2e-05 23.2 4.5 8.2e-05 23.2 4.5 3.0 2 1 1 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 KFM62142.1 - 0.0034 17.1 0.1 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM62142.1 - 0.012 15.6 3.0 0.017 15.1 1.8 1.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 KFM62142.1 - 0.018 14.9 0.3 0.19 11.6 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain GcrA PF07750.11 KFM62142.1 - 0.04 14.3 1.4 0.056 13.9 1.4 1.2 1 0 0 1 1 1 0 GcrA cell cycle regulator HTH_31 PF13560.6 KFM62142.1 - 1.8 8.9 8.1 1.6 9.2 0.3 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain HLH PF00010.26 KFM62143.1 - 0.0062 16.5 0.8 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HIG_1_N PF04588.13 KFM62148.1 - 2.1e-14 53.5 0.9 2.7e-14 53.1 0.9 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region LIP1 PF15904.5 KFM62149.1 - 2.2e-11 43.9 0.1 8.6e-11 42.0 0.1 2.0 1 0 0 1 1 1 1 LKB1 serine/threonine kinase interacting protein 1 LRR_8 PF13855.6 KFM62149.1 - 1e-09 38.0 27.1 7.6e-06 25.6 4.9 4.3 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFM62149.1 - 2e-09 37.6 36.0 0.00013 22.3 1.3 6.3 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM62149.1 - 0.00055 19.5 6.9 0.0076 15.8 1.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat RNA_pol_Rpa2_4 PF06883.12 KFM62149.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain LRR_6 PF13516.6 KFM62149.1 - 3.5 7.9 21.4 13 6.1 0.5 6.6 6 1 1 7 7 7 0 Leucine Rich repeat CBFD_NFYB_HMF PF00808.23 KFM62150.1 - 0.052 13.8 0.2 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hydrolase PF00702.26 KFM62152.1 - 5.4e-10 39.9 0.0 0.00048 20.5 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cyt_bd_oxida_I PF01654.17 KFM62152.1 - 0.017 13.8 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I E1-E2_ATPase PF00122.20 KFM62153.1 - 3e-31 108.4 0.3 6.8e-31 107.2 0.0 1.7 1 1 1 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 KFM62153.1 - 1.5e-14 54.2 0.9 1.5e-14 54.2 0.9 2.4 1 1 1 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 KFM62153.1 - 9.9e-08 31.6 0.0 2.8e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Peptidase_A17 PF05380.13 KFM62154.1 - 9.7e-55 185.0 0.0 4.8e-54 182.7 0.0 2.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 KFM62154.1 - 4.5e-38 130.5 0.3 4.5e-38 130.5 0.3 4.0 5 0 0 5 5 5 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM62154.1 - 5.6e-15 55.5 0.3 1.7e-14 53.9 0.3 1.8 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 KFM62154.1 - 2.6e-12 46.7 1.0 1.3e-11 44.4 0.2 2.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KFM62154.1 - 6.5e-11 42.5 0.0 2e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KFM62154.1 - 7.5e-05 22.3 0.2 0.00029 20.4 0.2 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 KFM62154.1 - 9.6e-05 23.0 0.0 0.00026 21.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM62154.1 - 0.029 14.9 0.1 0.083 13.5 0.1 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KFM62154.1 - 0.083 12.7 1.1 0.18 11.6 0.3 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF5639 PF18690.1 KFM62157.1 - 0.2 11.8 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5639) Hydrolase PF00702.26 KFM62159.1 - 1.4e-12 48.4 0.0 1.2e-05 25.7 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFM62160.1 - 6.1e-30 104.1 0.2 6.1e-30 104.1 0.2 1.6 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 KFM62160.1 - 5e-16 58.9 0.2 1.5e-15 57.4 0.2 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 KFM62160.1 - 8.3e-07 28.6 0.5 3.4e-06 26.6 0.0 2.2 2 1 1 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFM62161.1 - 4.6e-13 49.9 0.0 1.3e-05 25.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KFM62161.1 - 0.00026 20.7 6.9 0.00026 20.7 6.9 1.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus pXO2-72 PF17443.2 KFM62161.1 - 0.007 16.6 0.0 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein pXO2-72 Cyt_bd_oxida_I PF01654.17 KFM62161.1 - 0.011 14.4 1.3 0.017 13.8 1.3 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I HTH_Tnp_Tc3_2 PF01498.18 KFM62162.1 - 3e-16 59.4 3.0 6.3e-16 58.4 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62162.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62162.1 - 3.1e-07 30.0 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62162.1 - 0.0024 17.6 0.6 0.0082 15.9 0.6 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62162.1 - 8.1 7.1 15.6 0.13 12.9 1.9 3.4 3 1 1 4 4 4 0 Homeodomain-like domain DDE_3 PF13358.6 KFM62163.1 - 3.1e-06 27.0 0.0 3.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62164.1 - 2.1e-16 59.9 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62164.1 - 6.7e-14 51.9 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62165.1 - 7e-11 42.2 2.2 8.6e-11 41.9 1.1 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62165.1 - 1.4e-09 37.9 0.0 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM62165.1 - 0.0037 17.0 0.0 0.014 15.2 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM62165.1 - 0.033 14.0 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Tc3 transposase DUF3444 PF11926.8 KFM62166.1 - 0.13 11.8 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) 5-FTHF_cyc-lig PF01812.20 KFM62168.1 - 6.3e-21 75.1 0.3 6.8e-21 75.0 0.3 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DNA_pol_B_exo1 PF03104.19 KFM62169.1 - 1.5e-09 37.5 0.0 2.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KFM62170.1 - 3.5e-91 306.2 0.1 4.7e-91 305.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFM62170.1 - 8.9e-38 130.3 0.3 1.4e-37 129.6 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 KFM62170.1 - 0.001 18.0 0.4 0.0018 17.2 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KFM62170.1 - 0.024 14.3 0.0 0.048 13.3 0.0 1.5 1 1 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B PF00136.21 KFM62171.1 - 3e-37 128.4 0.1 3.5e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 KFM62171.1 - 1.9e-13 50.7 12.3 5e-13 49.3 12.3 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF3239 PF11580.8 KFM62171.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) Methyltransf_25 PF13649.6 KFM62172.1 - 2.9e-07 31.1 0.0 9.9e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KFM62172.1 - 3.1e-07 30.1 0.0 5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFM62172.1 - 1.7e-05 24.4 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KFM62172.1 - 5.7e-05 22.2 0.0 9.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 KFM62172.1 - 0.00016 22.2 0.0 0.0004 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 KFM62172.1 - 0.00019 21.3 0.1 0.00038 20.4 0.1 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_23 PF13489.6 KFM62172.1 - 0.00022 21.1 0.0 0.0005 19.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KFM62172.1 - 0.00048 20.0 0.0 0.00093 19.1 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CARM1 PF11531.8 KFM62172.1 - 0.0019 18.3 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 Coactivator-associated arginine methyltransferase 1 N terminal Methyltransf_31 PF13847.6 KFM62172.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM62172.1 - 0.037 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DREV PF05219.12 KFM62172.1 - 0.065 12.3 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_12 PF08242.12 KFM62172.1 - 0.071 13.9 0.0 0.27 12.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 KFM62172.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFM62172.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Med8 PF10232.9 KFM62173.1 - 5.9e-82 274.7 1.1 6.5e-82 274.6 1.1 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 LRS4 PF10422.9 KFM62173.1 - 1.3 8.5 9.4 0.023 14.3 1.5 2.0 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 DDE_3 PF13358.6 KFM62174.1 - 4.5e-05 23.2 0.0 6.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FAP206 PF12018.8 KFM62174.1 - 0.029 13.9 0.0 0.033 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function LRR_8 PF13855.6 KFM62175.1 - 1.1e-19 70.0 2.3 8.6e-14 51.1 0.6 3.5 1 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM62175.1 - 3.9e-14 52.5 6.0 2.8e-07 30.7 1.0 4.8 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM62175.1 - 8.1e-09 35.2 1.1 1.1e-06 28.2 0.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFM62175.1 - 1.2e-07 31.3 3.4 0.92 10.3 0.0 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_5 PF13306.6 KFM62175.1 - 6.3e-06 26.2 0.4 1.5e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFM62175.1 - 0.00013 21.7 10.3 0.082 13.0 0.3 5.1 6 0 0 6 6 6 2 Leucine Rich repeat HECT PF00632.25 KFM62175.1 - 0.024 14.1 0.5 0.081 12.4 0.3 1.9 1 1 1 2 2 2 0 HECT-domain (ubiquitin-transferase) Acyl-CoA_dh_1 PF00441.24 KFM62176.1 - 1.3e-32 113.1 2.0 1.5e-32 112.9 2.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KFM62176.1 - 2.8e-11 43.8 0.6 5.7e-11 42.8 0.6 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFM62176.1 - 0.00045 20.4 0.1 0.0015 18.6 0.0 1.9 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain zf-H2C2_2 PF13465.6 KFM62177.1 - 1.4e-55 183.3 55.1 9.7e-08 32.1 0.8 9.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62177.1 - 4.8e-41 137.0 64.3 6.4e-07 29.5 1.2 8.1 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62177.1 - 9.6e-31 103.8 59.8 0.00025 21.6 2.1 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM62177.1 - 1.7e-21 75.8 52.2 0.0027 18.0 0.0 8.3 8 0 0 8 8 8 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM62177.1 - 8.9e-13 48.2 41.0 0.14 12.5 0.1 8.4 7 1 1 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM62177.1 - 3.8e-10 39.3 34.2 0.033 13.9 0.3 8.1 8 0 0 8 8 8 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM62177.1 - 7.6e-10 38.5 50.9 0.049 13.7 0.4 8.9 8 1 1 9 9 9 5 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM62177.1 - 2.3e-06 27.4 26.6 3.6 7.6 0.1 8.2 8 0 0 8 8 8 2 zinc-finger of a C2HC-type BolA PF01722.18 KFM62177.1 - 1.3e-05 25.4 1.7 2.9 8.2 0.2 4.6 3 1 2 5 5 5 1 BolA-like protein zf-MYST PF17772.1 KFM62177.1 - 5.8e-05 22.6 27.6 0.16 11.6 0.0 7.8 5 1 3 8 8 8 1 MYST family zinc finger domain zf-DBF PF07535.12 KFM62177.1 - 0.00038 20.5 37.7 2.3 8.4 0.2 8.2 8 0 0 8 8 8 3 DBF zinc finger zf-Sec23_Sec24 PF04810.15 KFM62177.1 - 0.00039 20.4 36.1 0.12 12.4 0.8 8.0 5 1 3 8 8 8 2 Sec23/Sec24 zinc finger FYVE PF01363.21 KFM62177.1 - 0.00059 19.9 38.0 0.082 13.1 9.1 5.1 1 1 3 4 4 4 4 FYVE zinc finger GAGA PF09237.11 KFM62177.1 - 0.00074 19.3 19.8 1 9.2 0.0 6.7 2 2 6 8 8 8 2 GAGA factor DUF2256 PF10013.9 KFM62177.1 - 0.0032 17.5 28.0 5.3 7.3 0.1 8.0 8 0 0 8 8 8 1 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 KFM62177.1 - 0.0054 16.3 40.7 0.39 10.4 0.3 8.3 8 0 0 8 8 8 1 Ubiquitin-Binding Zinc Finger Thioredox_DsbH PF03190.15 KFM62177.1 - 0.031 14.2 1.5 2.8 7.9 0.0 3.0 2 2 1 3 3 3 0 Protein of unknown function, DUF255 Tox-HNH-HHH PF15637.6 KFM62177.1 - 0.04 14.1 0.2 3.8 7.7 0.0 3.2 1 1 1 3 3 3 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif PqqA PF08042.11 KFM62177.1 - 0.05 13.7 1.7 2.8e+02 1.7 0.0 5.2 6 0 0 6 6 6 0 PqqA family ADK_lid PF05191.14 KFM62177.1 - 0.072 13.1 30.0 2.5 8.2 2.3 5.7 4 2 2 6 6 6 0 Adenylate kinase, active site lid zf-RRPl_C4 PF17026.5 KFM62177.1 - 0.11 12.6 29.4 0.34 11.0 4.6 3.5 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-Dof PF02701.15 KFM62177.1 - 0.14 12.3 20.9 5.6 7.2 0.1 6.5 1 1 5 6 6 6 0 Dof domain, zinc finger zf-C2H2_11 PF16622.5 KFM62177.1 - 0.14 11.9 40.7 1.7 8.5 0.1 7.8 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFM62177.1 - 0.22 11.4 26.4 6.9 6.6 0.1 6.9 2 2 6 8 8 8 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM62177.1 - 0.45 11.3 29.3 3.4 8.5 2.5 4.3 1 1 2 4 4 4 0 zinc-ribbon family TRAF6_Z2 PF18048.1 KFM62177.1 - 1.2 9.3 37.2 1.4 9.1 0.7 7.3 7 0 0 7 7 7 0 TNF receptor-associated factor 6 zinc finger 2 Prok-RING_1 PF14446.6 KFM62177.1 - 1.7 8.7 36.4 12 5.9 0.6 7.8 7 1 0 8 8 8 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.12 KFM62177.1 - 1.8 8.6 31.3 63 3.6 5.1 5.8 1 1 2 3 3 2 0 zinc-ribbons zf-FCS PF06467.14 KFM62177.1 - 2.2 8.3 34.3 5.5 7.0 1.4 8.1 4 2 4 8 8 8 0 MYM-type Zinc finger with FCS sequence motif DUF4764 PF15961.5 KFM62177.1 - 8.5 4.9 23.1 4.3 5.9 0.1 5.7 3 3 3 6 6 6 0 Domain of unknown function (DUF4764) C1_4 PF07975.12 KFM62177.1 - 8.6 6.7 43.3 0.32 11.3 0.3 5.7 2 2 4 6 6 6 0 TFIIH C1-like domain zf-H2C2_2 PF13465.6 KFM62178.1 - 1.2e-58 193.1 58.0 1.6e-08 34.6 2.2 9.0 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62178.1 - 2.3e-42 141.1 63.0 2.1e-06 27.9 1.5 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62178.1 - 9.2e-32 107.0 57.4 0.0004 21.0 0.7 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM62178.1 - 3.4e-21 74.9 52.0 0.0036 17.6 1.3 8.2 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM62178.1 - 4.6e-15 55.5 35.0 0.047 14.0 0.4 8.4 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM62178.1 - 3.7e-10 39.5 52.5 0.12 12.4 0.5 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM62178.1 - 1.4e-08 34.3 39.6 0.4 10.5 0.7 8.3 8 0 0 8 8 8 5 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM62178.1 - 4.2e-08 32.8 37.1 0.035 13.9 0.5 8.4 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-Dof PF02701.15 KFM62178.1 - 0.00015 21.8 14.7 8.8 6.6 0.1 6.8 1 1 5 6 6 6 0 Dof domain, zinc finger zf-Sec23_Sec24 PF04810.15 KFM62178.1 - 0.00031 20.7 32.7 0.11 12.6 0.2 7.7 6 1 2 8 8 8 2 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM62178.1 - 0.00051 19.8 12.2 4.7 7.1 0.0 6.7 1 1 7 8 8 8 1 GAGA factor ADK_lid PF05191.14 KFM62178.1 - 0.00072 19.5 21.7 0.26 11.3 1.5 5.1 3 2 2 5 5 5 4 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM62178.1 - 0.00092 19.0 26.4 12 5.9 0.1 8.2 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM62178.1 - 0.0013 18.8 25.4 1.3 9.1 1.7 4.0 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 KFM62178.1 - 0.0018 18.1 42.6 3.1 7.8 0.1 8.0 4 1 4 8 8 8 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 KFM62178.1 - 0.002 18.2 21.4 10 6.3 0.1 7.8 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.18 KFM62178.1 - 0.0053 17.0 3.7 21 5.4 0.1 4.7 1 1 2 4 4 4 0 BolA-like protein zf_UBZ PF18439.1 KFM62178.1 - 0.0063 16.1 29.6 10 5.8 0.6 8.0 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 KFM62178.1 - 0.0097 16.0 36.6 1.1 9.5 9.4 5.8 1 1 4 5 5 5 1 FYVE zinc finger PqqA PF08042.11 KFM62178.1 - 0.023 14.7 0.2 2.9e+02 1.7 0.0 5.0 6 0 0 6 6 6 0 PqqA family HNH_5 PF14279.6 KFM62178.1 - 0.056 13.3 31.1 3.3 7.6 0.5 7.2 5 3 0 5 5 5 0 HNH endonuclease zf-C2H2_9 PF16293.5 KFM62178.1 - 0.083 12.7 28.2 13 5.7 0.1 7.7 2 2 6 8 8 8 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 KFM62178.1 - 0.097 12.7 21.1 1.8e+04 -9.2 21.1 4.8 1 1 0 1 1 0 0 Double zinc ribbon zf-DBF PF07535.12 KFM62178.1 - 0.11 12.6 31.6 4.5 7.5 0.5 7.1 7 1 1 8 8 7 0 DBF zinc finger Prok-RING_1 PF14446.6 KFM62178.1 - 0.31 11.0 29.3 8.2 6.4 0.1 7.9 8 0 0 8 8 8 0 Prokaryotic RING finger family 1 zf-MYST PF17772.1 KFM62178.1 - 0.46 10.1 23.7 16 5.2 0.0 7.0 5 2 3 8 8 8 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 KFM62178.1 - 0.51 10.7 43.4 1.3 9.4 13.1 6.3 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf_PR_Knuckle PF18445.1 KFM62178.1 - 0.59 10.0 20.2 2.8 7.8 0.1 6.5 8 0 0 8 8 7 0 PR zinc knuckle motif zf-Paramyx-P PF13008.7 KFM62178.1 - 0.78 9.3 18.8 34 4.0 0.1 6.9 7 0 0 7 7 7 0 Zinc-binding domain of Paramyxoviridae V protein zinc_ribbon_15 PF17032.5 KFM62178.1 - 2.1 9.1 24.6 2.8 8.8 5.4 4.2 1 1 3 4 4 4 0 zinc-ribbon family XPA_N PF01286.18 KFM62178.1 - 9.1 6.4 29.6 50 4.1 0.2 7.9 8 0 0 8 8 8 0 XPA protein N-terminal NAD_binding_1 PF00175.21 KFM62180.1 - 2.7e-20 73.0 0.0 3.9e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFM62180.1 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFM62180.1 - 3.2e-07 30.6 0.2 8.1e-05 22.8 0.2 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Forkhead PF00250.18 KFM62181.1 - 8.6e-24 83.6 2.2 4.6e-23 81.3 1.0 2.7 2 0 0 2 2 2 1 Forkhead domain DUF5569 PF17729.1 KFM62181.1 - 0.0038 17.1 6.3 0.33 10.8 0.1 3.0 2 1 0 3 3 3 2 Family of unknown function (DUF5569) Chitin_bind_4 PF00379.23 KFM62182.1 - 1.5e-12 47.9 3.8 2.1e-12 47.4 3.8 1.2 1 0 0 1 1 1 1 Insect cuticle protein Prokineticin PF06607.11 KFM62184.1 - 5.9e-06 26.5 6.2 1.2e-05 25.6 6.2 1.5 1 1 0 1 1 1 1 Prokineticin Nodulin_late PF07127.11 KFM62184.1 - 0.00088 19.6 1.5 0.00088 19.6 1.5 2.3 2 0 0 2 2 2 1 Late nodulin protein MIT_LIKE_ACTX PF17556.2 KFM62184.1 - 0.0058 17.2 10.9 0.33 11.6 10.9 2.3 1 1 0 1 1 1 1 MIT-like atracotoxin family I-set PF07679.16 KFM62185.1 - 3e-29 100.9 0.6 2.7e-22 78.6 0.0 4.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM62185.1 - 3.3e-20 72.5 1.6 2e-13 50.7 0.0 4.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM62185.1 - 7.6e-11 42.2 0.0 2.1e-08 34.4 0.0 2.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFM62185.1 - 6e-09 36.0 0.0 7.4e-08 32.5 0.0 3.1 2 0 0 2 2 2 1 Immunoglobulin domain SH3_1 PF00018.28 KFM62185.1 - 1.2e-07 31.2 0.0 3.7e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM62185.1 - 5.3e-05 22.8 0.1 0.00015 21.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFM62185.1 - 9.8e-05 22.1 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain V-set PF07686.17 KFM62185.1 - 0.00011 22.4 0.1 0.072 13.3 0.0 5.1 2 1 0 2 2 2 1 Immunoglobulin V-set domain AAA_27 PF13514.6 KFM62185.1 - 0.21 11.1 7.1 1.1e+02 2.3 0.1 5.2 5 0 0 5 5 5 0 AAA domain I-set PF07679.16 KFM62187.1 - 5.7e-37 125.7 0.7 1.8e-17 63.2 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM62187.1 - 1.5e-30 105.6 0.7 6.7e-14 52.3 0.2 4.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM62187.1 - 1e-17 64.2 0.7 1.7e-07 31.5 0.3 3.0 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM62187.1 - 6.2e-17 61.6 0.2 3.8e-08 33.4 0.1 3.5 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM62187.1 - 8.3e-08 32.2 0.2 0.0053 16.8 0.1 3.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain MinC_C PF03775.16 KFM62187.1 - 4.8e-05 23.3 4.7 1e+02 3.0 0.0 9.8 10 0 0 10 10 10 0 Septum formation inhibitor MinC, C-terminal domain V-set PF07686.17 KFM62187.1 - 0.00013 22.1 0.8 0.094 12.9 0.2 5.1 2 2 0 2 2 2 1 Immunoglobulin V-set domain V-set_CD47 PF08204.11 KFM62187.1 - 0.04 13.9 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFM62187.1 - 0.13 12.1 0.3 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 I-set PF07679.16 KFM62188.1 - 5.2e-13 48.9 0.0 5.5e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM62188.1 - 3.8e-09 37.0 0.0 4.1e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM62188.1 - 1.4e-06 28.4 0.0 1.5e-06 28.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM62188.1 - 3.7e-05 24.0 0.0 4.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_4 PF16680.5 KFM62188.1 - 0.013 15.7 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 KFM62188.1 - 0.018 15.2 0.0 0.019 15.2 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM62188.1 - 0.072 13.5 0.1 0.093 13.1 0.1 1.4 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DDE_Tnp_1_7 PF13843.6 KFM62189.1 - 2e-69 234.6 0.9 2.5e-69 234.3 0.9 1.1 1 0 0 1 1 1 1 Transposase IS4 RGM_N PF06535.12 KFM62189.1 - 0.045 13.9 0.3 0.09 13.0 0.3 1.4 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus G5 PF07501.12 KFM62189.1 - 0.23 11.9 0.7 0.53 10.7 0.7 1.5 1 0 0 1 1 1 0 G5 domain I-set PF07679.16 KFM62190.1 - 0 1629.6 0.0 7.1e-23 80.5 0.0 30.3 30 0 0 30 30 30 30 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM62190.1 - 0 1069.7 0.0 1.1e-12 48.3 0.1 30.5 30 0 0 30 30 30 30 Immunoglobulin domain ig PF00047.25 KFM62190.1 - 2.5e-207 671.8 0.7 1.7e-09 37.7 0.0 31.9 30 1 1 31 31 31 30 Immunoglobulin domain Ig_2 PF13895.6 KFM62190.1 - 5.7e-197 638.6 4.9 1.1e-08 35.2 0.0 30.4 30 0 0 30 30 30 29 Immunoglobulin domain Titin_Ig-rpts PF06582.12 KFM62190.1 - 3e-134 436.4 161.2 1.9e-13 50.1 2.5 22.1 23 0 0 23 23 22 19 Titin repeat V-set PF07686.17 KFM62190.1 - 5.6e-92 303.2 45.7 0.00053 20.1 0.1 42.8 30 20 1 31 31 31 19 Immunoglobulin V-set domain C1-set PF07654.15 KFM62190.1 - 3.9e-61 203.4 0.0 0.23 11.9 0.0 26.2 26 0 0 26 26 26 10 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFM62190.1 - 4.4e-41 138.2 31.8 0.27 10.8 0.0 24.8 25 0 0 25 25 25 8 Immunoglobulin domain C2-set_2 PF08205.12 KFM62190.1 - 1.4e-30 105.2 0.0 1 9.4 0.0 20.2 23 0 0 23 23 23 5 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 KFM62190.1 - 4.8e-30 103.4 0.0 3.8 7.6 0.0 22.5 26 0 0 26 26 25 2 Penicillin-Binding Protein C-terminus Family Ig_4 PF16680.5 KFM62190.1 - 7.8e-27 93.4 11.3 1.9 8.8 0.0 21.9 23 1 1 24 24 21 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFM62190.1 - 4.4e-22 78.3 0.0 0.95 9.7 0.0 19.0 25 0 0 25 25 21 1 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 KFM62190.1 - 2.8e-20 72.6 19.9 0.4 10.7 0.0 22.3 25 4 0 25 25 23 2 CD47 immunoglobulin-like domain Ig_5 PF16681.5 KFM62190.1 - 6e-12 45.8 8.4 40 4.7 0.0 17.6 22 0 0 22 22 18 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFM62190.1 - 5.1e-09 36.1 28.4 12 6.0 0.0 17.3 24 0 0 24 24 21 0 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM62190.1 - 5.1e-09 36.0 35.5 14 5.8 0.0 20.9 26 1 1 27 27 26 0 C17orf99 Ig domain MetallophosC PF16370.5 KFM62190.1 - 4.2e-07 30.3 0.0 1.1e+02 3.0 0.0 12.7 19 0 0 19 19 17 0 C terminal of Calcineurin-like phosphoesterase DUF4508 PF14969.6 KFM62190.1 - 0.027 14.7 9.0 6.9 7.0 0.2 6.4 6 0 0 6 6 6 0 Domain of unknown function (DUF4508) PSRT PF07636.11 KFM62190.1 - 0.048 13.4 1.4 2e+02 1.8 0.0 6.7 10 0 0 10 10 10 0 PSRT Egh16-like PF11327.8 KFM62190.1 - 0.2 12.0 6.5 85 3.5 0.1 7.6 10 2 1 12 12 9 0 Egh16-like virulence factor I-set PF07679.16 KFM62191.1 - 1.5e-17 63.4 0.0 2.1e-11 43.7 0.0 2.5 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM62191.1 - 4.4e-09 36.8 0.0 4.1e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM62191.1 - 0.00029 20.9 0.0 0.04 14.1 0.0 2.5 2 1 1 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM62191.1 - 0.0039 17.2 0.0 0.062 13.4 0.0 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFM62191.1 - 0.0041 17.4 0.0 0.52 10.7 0.0 2.4 2 1 1 3 3 3 1 Immunoglobulin domain BiPBP_C PF06832.12 KFM62191.1 - 0.06 13.4 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Tir_receptor_C PF07489.11 KFM62191.1 - 0.18 11.8 4.3 0.19 11.6 4.2 1.3 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus I-set PF07679.16 KFM62192.1 - 2.1e-19 69.4 0.0 3.7e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM62192.1 - 8.3e-14 52.0 0.3 3.1e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFM62192.1 - 5.6e-08 32.8 0.2 1.2e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM62192.1 - 5.7e-07 29.8 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM62192.1 - 0.014 15.5 0.1 0.1 12.8 0.1 2.2 1 1 0 1 1 1 0 Immunoglobulin V-set domain HTH_Tnp_Tc3_2 PF01498.18 KFM62193.1 - 2.5e-16 59.7 2.2 7e-16 58.2 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62193.1 - 1.6e-13 50.6 0.0 2.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62193.1 - 3.2e-07 30.0 1.6 8.3e-07 28.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62193.1 - 0.0032 17.2 0.5 0.009 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62193.1 - 0.036 14.2 0.4 0.11 12.7 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM62193.1 - 2.8 8.6 15.6 0.15 12.7 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain I-set PF07679.16 KFM62194.1 - 4.5e-172 558.7 0.8 6.3e-22 77.4 0.0 8.7 8 0 0 8 8 8 8 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM62194.1 - 2e-113 371.1 11.0 4e-14 53.0 0.0 9.5 9 0 0 9 9 8 8 Immunoglobulin domain Ig_2 PF13895.6 KFM62194.1 - 2.1e-72 239.4 5.3 1.4e-11 44.6 0.0 8.8 8 0 0 8 8 8 8 Immunoglobulin domain ig PF00047.25 KFM62194.1 - 4.7e-53 177.3 1.7 7.3e-07 29.3 0.0 8.8 8 0 0 8 8 8 8 Immunoglobulin domain Spectrin PF00435.21 KFM62194.1 - 3.8e-30 104.5 67.8 5.4e-08 33.3 0.1 10.0 10 1 0 10 10 10 6 Spectrin repeat V-set PF07686.17 KFM62194.1 - 1e-17 64.2 12.2 0.017 15.2 0.0 12.3 8 7 1 9 9 9 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM62194.1 - 2.5e-15 56.3 14.5 0.024 14.7 0.0 9.1 9 0 0 9 9 8 5 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM62194.1 - 1.7e-10 41.1 0.9 0.058 13.8 0.0 8.0 8 0 0 8 8 8 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM62194.1 - 6.8e-08 32.7 2.1 1.5 9.1 0.0 7.5 8 0 0 8 8 8 2 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFM62194.1 - 2.2e-07 31.0 0.2 2.4 8.4 0.0 6.4 6 0 0 6 6 6 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFM62194.1 - 3.5e-06 27.0 0.0 0.079 13.0 0.0 5.7 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM62194.1 - 0.0031 17.5 2.0 1e+02 3.0 0.0 6.6 7 0 0 7 7 7 0 C17orf99 Ig domain SAC3 PF12209.8 KFM62194.1 - 0.046 13.9 0.1 0.19 11.9 0.1 2.1 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain Ig_6 PF18452.1 KFM62194.1 - 0.2 11.3 5.3 1.8 8.2 0.0 4.0 5 0 0 5 5 5 0 Immunoglobulin domain SOAR PF16533.5 KFM62194.1 - 2.7 8.0 8.8 7.1 6.7 0.2 4.5 3 0 0 3 3 3 0 STIM1 Orai1-activating region eIF-5a PF01287.20 KFM62195.1 - 0.19 11.8 1.5 8.9 6.5 0.2 2.6 2 1 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Thioredoxin_6 PF13848.6 KFM62196.1 - 2.6e-45 154.6 0.0 2.4e-42 144.9 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFM62196.1 - 8e-21 74.0 0.0 2e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Calsequestrin PF01216.17 KFM62196.1 - 4.4e-08 32.6 0.2 8.9e-08 31.6 0.2 1.4 1 0 0 1 1 1 1 Calsequestrin OST3_OST6 PF04756.13 KFM62196.1 - 0.0057 16.0 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFM62196.1 - 0.031 14.7 0.0 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain HyaE PF07449.11 KFM62196.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DFRP_C PF16543.5 KFM62197.1 - 9.2e-23 80.5 7.4 9.2e-23 80.5 7.4 3.5 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 KFM62197.1 - 5e-08 33.6 19.2 1.8e-05 25.4 4.2 4.0 1 1 2 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 KFM62197.1 - 3.1e-07 30.0 10.1 1.5e-06 27.8 1.1 3.1 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 KFM62197.1 - 9.5e-07 28.6 1.0 9.5e-07 28.6 1.0 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM62197.1 - 1.3e-06 28.3 6.3 1.3e-06 28.3 6.3 3.2 3 1 0 3 3 3 1 Zinc finger domain zf-CCCH_2 PF14608.6 KFM62197.1 - 0.031 14.8 2.1 0.031 14.8 2.1 2.6 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF4354 PF14263.6 KFM62197.1 - 0.15 11.9 1.5 0.29 11.0 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) zf-CCCH_3 PF15663.5 KFM62197.1 - 0.17 12.1 8.9 0.074 13.3 1.8 3.2 3 1 0 3 3 3 0 Zinc-finger containing family wnt PF00110.19 KFM62198.1 - 1.6e-65 221.7 11.6 1.8e-65 221.6 11.6 1.0 1 0 0 1 1 1 1 wnt family HTH_Tnp_Tc3_2 PF01498.18 KFM62199.1 - 4.3e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62199.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62199.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62199.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62199.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Yip1 PF04893.17 KFM62203.1 - 0.0042 16.8 0.8 0.0053 16.5 0.8 1.1 1 0 0 1 1 1 1 Yip1 domain CNH PF00780.22 KFM62204.1 - 7.8e-55 186.4 0.0 2.1e-54 185.0 0.0 1.7 1 1 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFM62204.1 - 2e-09 37.2 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM62204.1 - 1.5e-05 24.4 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CS PF04969.16 KFM62205.1 - 3.9e-15 56.6 0.5 6.2e-15 56.0 0.5 1.3 1 0 0 1 1 1 1 CS domain SGS PF05002.15 KFM62205.1 - 4.8e-05 23.4 2.9 0.0001 22.4 2.9 1.5 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.11 KFM62205.1 - 0.073 13.4 0.3 0.073 13.4 0.3 1.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal HlyIII PF03006.20 KFM62206.1 - 1.2e-33 116.7 18.7 1.2e-33 116.7 18.7 1.7 2 0 0 2 2 2 1 Haemolysin-III related Sigma_reg_N PF13800.6 KFM62206.1 - 4.5 7.6 5.0 0.79 10.1 0.1 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TMEMspv1-c74-12 PF11044.8 KFM62207.1 - 0.0085 16.0 0.6 0.013 15.5 0.6 1.3 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Connexin PF00029.19 KFM62207.1 - 0.0091 15.8 0.0 0.0097 15.7 0.0 1.0 1 0 0 1 1 1 1 Connexin UPF0542 PF15086.6 KFM62207.1 - 0.012 15.6 0.4 0.014 15.3 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 OFeT_1 PF16955.5 KFM62207.1 - 0.2 11.3 0.1 0.21 11.3 0.1 1.0 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter FAM165 PF14981.6 KFM62207.1 - 1.9 8.3 6.0 4.3 7.2 6.0 1.7 1 1 0 1 1 1 0 FAM165 family HTH_Tnp_Tc3_2 PF01498.18 KFM62208.1 - 2.1e-16 59.9 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62208.1 - 7.7e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ldl_recept_a PF00057.18 KFM62209.1 - 9.6e-14 51.3 36.7 3.4e-05 24.0 8.5 4.2 2 1 2 4 4 3 3 Low-density lipoprotein receptor domain class A SEA PF01390.20 KFM62209.1 - 7.7e-10 38.8 0.4 4e-09 36.5 0.3 2.5 2 0 0 2 2 2 1 SEA domain EGF_CA PF07645.15 KFM62209.1 - 2.1e-08 34.2 7.1 2.1e-08 34.2 7.1 4.5 3 2 2 5 5 4 1 Calcium-binding EGF domain EGF PF00008.27 KFM62209.1 - 3.7e-05 23.9 5.0 3.7e-05 23.9 5.0 4.6 4 1 0 4 4 3 2 EGF-like domain EGF_3 PF12947.7 KFM62209.1 - 0.00024 21.2 6.2 0.00024 21.2 6.2 3.6 3 0 0 3 3 2 1 EGF domain DUF4758 PF15950.5 KFM62209.1 - 0.00028 21.2 30.5 0.00043 20.6 6.1 11.7 10 3 2 12 12 9 5 Putative sperm flagellar membrane protein FXa_inhibition PF14670.6 KFM62209.1 - 0.0006 20.0 4.6 0.0006 20.0 4.6 3.9 4 0 0 4 4 2 1 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFM62209.1 - 0.0012 19.4 1.6 0.0012 19.4 1.6 4.2 4 0 0 4 4 3 1 Human growth factor-like EGF PRKCSH-like PF12999.7 KFM62209.1 - 0.0048 16.7 12.8 0.0048 16.7 12.8 3.3 2 1 1 3 3 2 2 Glucosidase II beta subunit-like DNA_pol_phi PF04931.13 KFM62209.1 - 0.067 11.3 4.7 0.11 10.6 4.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi PapA_C PF16911.5 KFM62209.1 - 0.084 13.0 0.1 0.31 11.1 0.1 2.0 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus CobT PF06213.12 KFM62209.1 - 0.11 11.8 0.6 0.2 11.0 0.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT cEGF PF12662.7 KFM62209.1 - 0.97 9.4 17.8 0.21 11.6 0.6 3.4 3 0 0 3 3 2 0 Complement Clr-like EGF-like CRF-BP PF05428.11 KFM62210.1 - 1.8e-14 53.3 0.1 2.2e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 Corticotropin-releasing factor binding protein (CRF-BP) HTH_Tnp_Tc3_2 PF01498.18 KFM62212.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62212.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62212.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62212.1 - 0.0023 17.6 0.6 0.0068 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62212.1 - 1.8 9.2 15.7 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Strep_SA_rep PF06696.11 KFM62213.1 - 0.0032 17.4 4.2 0.73 9.9 0.3 3.0 2 2 1 3 3 3 2 Streptococcal surface antigen repeat Syntaxin PF00804.25 KFM62213.1 - 0.025 14.2 2.2 0.028 14.1 2.2 1.0 1 0 0 1 1 1 0 Syntaxin DUF842 PF05811.13 KFM62213.1 - 0.038 13.7 1.7 0.048 13.4 1.7 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF1640 PF07798.11 KFM62213.1 - 0.058 13.4 1.9 0.063 13.3 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) YtxH PF12732.7 KFM62213.1 - 0.08 13.5 6.1 0.096 13.2 6.1 1.1 1 0 0 1 1 1 0 YtxH-like protein FAM25 PF15825.5 KFM62213.1 - 1.9 8.9 8.8 12 6.3 8.1 1.9 1 1 0 1 1 1 0 FAM25 family HTH_Tnp_Tc3_2 PF01498.18 KFM62214.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62214.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Rad51 PF08423.11 KFM62215.1 - 2.1e-45 155.0 0.0 3.7e-45 154.2 0.0 1.3 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFM62215.1 - 2.4e-08 33.8 0.0 3.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFM62215.1 - 8.2e-08 31.9 1.8 2.3e-07 30.4 1.8 1.8 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KFM62215.1 - 2.8e-06 27.0 0.7 0.0014 18.1 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_24 PF13479.6 KFM62215.1 - 3.7e-05 23.5 0.0 6.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFM62215.1 - 0.0045 17.4 0.9 0.0045 17.4 0.9 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM62215.1 - 0.017 15.4 0.2 0.076 13.3 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFM62215.1 - 0.02 15.5 0.1 0.062 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFM62215.1 - 0.047 13.6 0.5 0.21 11.5 0.5 2.1 1 1 0 1 1 1 0 NTPase zf-H2C2_2 PF13465.6 KFM62216.1 - 4.5e-07 30.0 5.3 9.8e-07 28.9 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62216.1 - 0.00035 20.9 10.6 0.0023 18.3 3.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62216.1 - 0.0006 20.4 9.3 0.0045 17.7 3.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM62216.1 - 0.0064 16.9 13.5 0.05 14.0 3.1 3.1 2 1 0 2 2 2 1 Zinc-finger of C2H2 type C1_4 PF07975.12 KFM62216.1 - 0.019 15.2 4.9 0.024 14.8 4.9 1.2 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 KFM62216.1 - 0.035 14.1 5.3 0.093 12.8 5.3 1.7 1 1 0 1 1 1 0 C2H2-type zinc finger Zf_RING PF16744.5 KFM62216.1 - 0.091 12.9 5.3 0.3 11.2 5.3 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger IBR PF01485.21 KFM62216.1 - 0.12 12.6 6.7 0.17 12.1 6.7 1.3 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain TRAF6_Z2 PF18048.1 KFM62216.1 - 1 9.5 8.2 7.2 6.8 0.6 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-H2C2_2 PF13465.6 KFM62217.1 - 8.5e-26 89.2 31.1 1.8e-08 34.4 1.1 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62217.1 - 1.5e-20 72.4 34.8 4e-05 23.8 2.3 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62217.1 - 1.4e-15 56.6 33.1 0.0011 19.7 2.2 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFM62217.1 - 6.1e-14 51.9 33.2 0.00016 21.9 1.0 4.2 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM62217.1 - 1.4e-13 50.5 30.3 0.00028 20.8 2.1 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM62217.1 - 5e-09 35.8 23.5 0.0067 16.2 1.0 4.1 4 0 0 4 4 4 4 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM62217.1 - 6.5e-07 29.3 9.2 0.028 14.4 0.3 4.1 1 1 2 4 4 4 2 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KFM62217.1 - 1.1e-05 25.5 25.4 0.061 13.6 0.8 4.5 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 KFM62217.1 - 6.2e-05 23.0 8.1 4.4 7.5 0.3 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 KFM62217.1 - 0.00015 21.3 11.9 0.79 9.4 0.1 4.2 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM62217.1 - 0.00017 21.4 9.9 4.4 7.3 0.1 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type C1_4 PF07975.12 KFM62217.1 - 0.00064 19.9 20.9 0.022 15.0 7.2 3.2 1 1 0 2 2 2 1 TFIIH C1-like domain Zn_ribbon_SprT PF17283.2 KFM62217.1 - 0.0012 18.8 4.3 0.4 10.6 0.2 2.9 1 1 2 3 3 3 2 SprT-like zinc ribbon domain Zf_RING PF16744.5 KFM62217.1 - 0.0012 18.9 15.7 1.5 9.0 0.2 4.0 1 1 2 3 3 3 2 KIAA1045 RING finger C1_1 PF00130.22 KFM62217.1 - 0.0027 17.6 16.1 0.35 10.8 6.0 3.2 1 1 2 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FAO_M PF16350.5 KFM62217.1 - 0.0046 17.3 0.3 12 6.3 0.0 3.0 1 1 2 3 3 3 0 FAD dependent oxidoreductase central domain TerY_C PF15616.6 KFM62217.1 - 0.0088 16.2 4.7 1.2 9.3 1.2 2.1 1 1 1 2 2 2 2 TerY-C metal binding domain zinc_ribbon_15 PF17032.5 KFM62217.1 - 0.012 16.4 11.8 0.2 12.4 2.4 2.1 1 1 1 2 2 2 0 zinc-ribbon family zf-MYST PF17772.1 KFM62217.1 - 0.02 14.5 22.8 0.7 9.5 0.8 4.0 1 1 3 4 4 4 0 MYST family zinc finger domain zinc-ribbons_6 PF07191.12 KFM62217.1 - 0.021 14.8 12.7 8.2 6.5 0.1 3.3 1 1 0 2 2 2 0 zinc-ribbons zf-trcl PF13451.6 KFM62217.1 - 0.027 14.4 14.1 7.4 6.6 0.4 4.1 4 0 0 4 4 4 0 Probable zinc-ribbon domain BolA PF01722.18 KFM62217.1 - 0.03 14.6 2.6 4 7.8 0.2 2.7 1 1 1 2 2 2 0 BolA-like protein MCR_D PF02505.14 KFM62217.1 - 0.032 14.1 1.2 30 4.4 0.1 3.3 1 1 3 4 4 4 0 Methyl-coenzyme M reductase operon protein D FYVE PF01363.21 KFM62217.1 - 0.054 13.6 18.4 0.43 10.7 11.6 2.9 1 1 2 3 3 3 0 FYVE zinc finger PHD PF00628.29 KFM62217.1 - 0.061 13.2 15.0 4.6 7.2 12.1 2.9 2 1 0 2 2 2 0 PHD-finger zf-FPG_IleRS PF06827.14 KFM62217.1 - 0.065 13.1 8.4 11 5.9 0.1 4.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-HIT PF04438.16 KFM62217.1 - 0.097 12.6 17.9 0.22 11.4 2.9 4.1 4 0 0 4 4 4 0 HIT zinc finger CpXC PF14353.6 KFM62217.1 - 0.12 12.4 11.9 9.4 6.3 0.1 3.9 1 1 1 3 3 3 0 CpXC protein zf-C2H2_8 PF15909.5 KFM62217.1 - 0.12 12.6 17.4 1.4 9.2 10.3 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon DUF5330 PF17264.2 KFM62217.1 - 0.16 12.0 1.3 56 3.8 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5330) DZR PF12773.7 KFM62217.1 - 0.17 11.9 10.4 50 4.0 10.4 2.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_2 PF12756.7 KFM62217.1 - 0.23 11.8 24.7 3.3 8.1 0.4 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) TRAF6_Z2 PF18048.1 KFM62217.1 - 0.24 11.5 11.4 0.94 9.6 0.6 3.7 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 HNH PF01844.23 KFM62217.1 - 0.25 11.5 18.2 11 6.2 0.5 4.1 4 0 0 4 4 4 0 HNH endonuclease zf-RING_UBOX PF13445.6 KFM62217.1 - 0.3 11.2 6.7 60 3.8 0.1 4.0 4 0 0 4 4 4 0 RING-type zinc-finger ADK_lid PF05191.14 KFM62217.1 - 0.72 9.9 15.2 11 6.0 0.2 3.7 1 1 3 4 4 4 0 Adenylate kinase, active site lid A2L_zn_ribbon PF08792.10 KFM62217.1 - 0.79 9.5 15.8 9.7 6.0 0.5 4.3 4 0 0 4 4 4 0 A2L zinc ribbon domain Zn-C2H2_12 PF18112.1 KFM62217.1 - 0.98 9.9 27.5 1.5 9.4 0.5 4.8 4 2 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_4 PF13717.6 KFM62217.1 - 1 9.3 12.6 27 4.8 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-DBF PF07535.12 KFM62217.1 - 1.1 9.4 24.3 9.9 6.4 0.9 4.4 3 1 1 4 4 4 0 DBF zinc finger FYDLN_acid PF09538.10 KFM62217.1 - 1.2 9.9 4.9 20 5.9 0.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-RRPl_C4 PF17026.5 KFM62217.1 - 1.7 8.8 16.2 3.9 7.6 6.0 2.4 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 KFM62217.1 - 2.2 8.5 16.6 2 8.6 3.5 3.7 1 1 3 4 4 4 0 Zinc ribbon domain zf-piccolo PF05715.13 KFM62217.1 - 2.3 8.4 13.5 1.5 9.0 8.3 2.5 1 1 1 2 2 2 0 Piccolo Zn-finger zf-C2H2_9 PF16293.5 KFM62217.1 - 2.4 8.1 17.0 9.7 6.1 0.2 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (1 copy) DUF3268 PF11672.8 KFM62217.1 - 2.9 8.3 11.0 2 8.8 1.6 2.5 1 1 2 3 3 3 0 zinc-finger-containing domain PknG_rubred PF16919.5 KFM62217.1 - 3.2 7.9 8.4 7 6.8 0.2 3.5 1 1 3 4 4 4 0 Protein kinase G rubredoxin domain Prok-RING_2 PF14445.6 KFM62217.1 - 3.9 7.7 8.4 65 3.8 0.1 3.6 3 1 0 4 4 4 0 Prokaryotic RING finger family 2 IBR PF01485.21 KFM62217.1 - 5.8 7.2 22.1 6.4 7.1 9.0 3.8 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-FCS PF06467.14 KFM62217.1 - 6.6 6.8 17.5 2.8 8.0 0.4 4.0 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-RING_5 PF14634.6 KFM62217.1 - 6.7 6.8 14.0 43 4.2 0.0 3.5 2 1 0 2 2 2 0 zinc-RING finger domain zf-MYND PF01753.18 KFM62217.1 - 6.9 6.9 12.6 23 5.2 4.7 2.8 1 1 1 2 2 1 0 MYND finger zf-H2C2_2 PF13465.6 KFM62218.1 - 7.7e-38 127.3 35.6 7.1e-09 35.7 1.0 6.2 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62218.1 - 2.8e-26 90.5 40.4 5.6e-06 26.5 1.4 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62218.1 - 8.6e-19 66.6 35.2 0.00027 21.5 1.2 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM62218.1 - 1.7e-12 47.3 36.7 0.0052 17.1 0.9 5.5 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM62218.1 - 9e-07 28.5 19.4 0.014 15.1 0.1 6.0 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM62218.1 - 9.2e-06 25.3 28.2 0.00025 20.7 0.2 4.9 5 0 0 5 5 5 3 zinc-finger C2H2-type BolA PF01722.18 KFM62218.1 - 1.2e-05 25.5 1.9 2 8.7 0.1 4.0 1 1 3 4 4 4 2 BolA-like protein zf-C2H2_6 PF13912.6 KFM62218.1 - 2.1e-05 24.4 38.1 0.063 13.3 1.0 5.9 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM62218.1 - 8.4e-05 22.8 30.9 1.2 9.6 1.0 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM62218.1 - 0.00035 20.4 22.0 1.9 8.5 0.6 5.4 5 0 0 5 5 5 3 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM62218.1 - 0.0011 19.0 15.0 3.5 7.8 2.2 5.2 2 1 3 5 5 5 1 Sec23/Sec24 zinc finger TRAF6_Z2 PF18048.1 KFM62218.1 - 0.0035 17.4 20.1 2.5 8.3 0.6 5.6 4 1 2 6 6 6 2 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_9 PF16293.5 KFM62218.1 - 0.011 15.5 15.6 6.9 6.6 0.3 5.0 1 1 4 5 5 5 0 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFM62218.1 - 0.012 15.7 19.5 14 5.9 0.1 5.4 4 1 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Zf_RING PF16744.5 KFM62218.1 - 0.058 13.5 26.6 2.5 8.3 1.4 5.1 1 1 3 5 5 5 0 KIAA1045 RING finger zf-DBF PF07535.12 KFM62218.1 - 0.075 13.2 22.2 2 8.6 0.2 5.1 5 0 0 5 5 5 0 DBF zinc finger C1_1 PF00130.22 KFM62218.1 - 0.081 12.8 24.9 1.2 9.1 3.3 4.4 2 2 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM62218.1 - 0.087 12.6 9.5 0.22 11.4 0.4 3.9 1 1 3 4 4 4 0 GAGA factor zf-C2H2_2 PF12756.7 KFM62218.1 - 0.2 12.0 30.7 4.2 7.8 0.6 5.0 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Baculo_IE-1 PF05290.11 KFM62218.1 - 0.31 11.0 20.2 1.8e+04 -4.8 20.4 4.7 1 1 0 1 1 0 0 Baculovirus immediate-early protein (IE-0) zinc_ribbon_15 PF17032.5 KFM62218.1 - 0.35 11.7 21.0 0.25 12.1 1.3 3.1 1 1 1 3 3 3 0 zinc-ribbon family zf-MYST PF17772.1 KFM62218.1 - 0.63 9.7 29.6 1 9.0 1.3 5.4 2 1 4 6 6 6 0 MYST family zinc finger domain zf_UBZ PF18439.1 KFM62218.1 - 1.2 8.8 20.1 1.3 8.7 0.2 5.2 6 0 0 6 6 5 0 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM62218.1 - 2.7 8.1 24.2 3 8.0 2.5 3.0 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type FYVE PF01363.21 KFM62218.1 - 3.4 7.9 27.3 2.2e+02 2.1 14.9 3.7 1 1 1 2 2 2 0 FYVE zinc finger zf-FPG_IleRS PF06827.14 KFM62218.1 - 3.8 7.5 15.2 12 5.9 0.1 4.7 5 0 0 5 5 4 0 Zinc finger found in FPG and IleRS zf-trcl PF13451.6 KFM62218.1 - 4.5 7.3 19.8 12 5.9 0.4 5.1 5 0 0 5 5 5 0 Probable zinc-ribbon domain C1_4 PF07975.12 KFM62218.1 - 5 7.4 25.3 9.7 6.5 3.5 3.8 2 2 2 4 4 4 0 TFIIH C1-like domain PknG_rubred PF16919.5 KFM62218.1 - 7.1 6.8 7.1 34 4.6 0.4 3.1 1 1 3 4 4 3 0 Protein kinase G rubredoxin domain DUF5330 PF17264.2 KFM62218.1 - 7.5 6.6 15.2 31 4.7 0.2 5.3 6 0 0 6 6 6 0 Family of unknown function (DUF5330) zf-HIT PF04438.16 KFM62218.1 - 7.7 6.5 23.6 10 6.1 0.4 5.4 5 0 0 5 5 5 0 HIT zinc finger Vps39_2 PF10367.9 KFM62218.1 - 7.8 7.0 26.9 13 6.3 0.5 5.0 1 1 3 5 5 5 0 Vacuolar sorting protein 39 domain 2 zf-H2C2_2 PF13465.6 KFM62220.1 - 9.3e-143 459.0 149.8 1.4e-08 34.7 0.4 21.3 21 0 0 21 21 21 20 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62220.1 - 3.2e-98 317.0 183.9 9.4e-06 25.8 0.6 20.1 20 0 0 20 20 20 20 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62220.1 - 1.2e-68 221.8 176.5 0.00024 21.6 0.9 20.1 20 0 0 20 20 20 20 C2H2-type zinc finger zf-met PF12874.7 KFM62220.1 - 2.5e-49 164.3 179.7 0.00011 22.4 1.8 20.2 20 0 0 20 20 20 18 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM62220.1 - 7.5e-22 77.1 132.1 0.0054 17.0 0.6 20.5 19 1 1 20 20 20 11 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM62220.1 - 2.8e-21 75.0 117.0 0.02 14.6 0.1 20.3 20 0 0 20 20 20 12 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM62220.1 - 1.9e-12 46.8 150.4 0.038 14.0 1.7 20.2 20 0 0 20 20 20 14 C2H2-type zinc finger BolA PF01722.18 KFM62220.1 - 4.2e-12 46.2 33.6 0.18 12.1 0.1 12.7 1 1 7 11 11 11 3 BolA-like protein zf-C2H2_11 PF16622.5 KFM62220.1 - 8.8e-09 35.0 156.8 0.001 18.7 0.3 19.4 20 0 0 20 20 20 9 zinc-finger C2H2-type Tox-HNH-HHH PF15637.6 KFM62220.1 - 2.6e-06 27.5 4.3 8.3 6.6 0.0 6.6 2 2 6 8 8 8 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif Complex1_49kDa PF00346.19 KFM62220.1 - 6.3e-05 22.2 14.5 1.1 8.3 0.1 6.0 1 1 5 6 6 6 4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit GAGA PF09237.11 KFM62220.1 - 0.00011 22.0 63.9 0.039 13.8 0.0 13.6 3 3 14 18 18 18 3 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM62220.1 - 0.01 15.8 83.7 1 9.4 0.6 18.4 16 4 4 20 20 19 0 Sec23/Sec24 zinc finger NAD_kinase PF01513.21 KFM62220.1 - 0.23 10.6 2.0 24 4.0 0.0 3.5 4 0 0 4 4 4 0 ATP-NAD kinase Amidohydro_1 PF01979.20 KFM62220.1 - 0.79 9.0 21.8 2.9 7.1 0.3 6.6 2 2 4 7 7 7 0 Amidohydrolase family C1_4 PF07975.12 KFM62220.1 - 0.96 9.7 117.6 0.11 12.7 3.5 13.1 5 4 9 15 15 15 0 TFIIH C1-like domain zf-MYST PF17772.1 KFM62220.1 - 2.2 8.0 115.4 0.83 9.3 0.2 18.9 6 3 14 20 20 20 0 MYST family zinc finger domain Zf_RING PF16744.5 KFM62220.1 - 3 8.0 115.1 2 8.6 2.5 18.9 1 1 15 18 18 16 0 KIAA1045 RING finger HTH_48 PF17906.1 KFM62221.1 - 1.1e-06 28.7 0.6 2.2e-06 27.7 0.6 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase PCI PF01399.27 KFM62221.1 - 0.003 18.1 0.2 0.0046 17.4 0.2 1.4 1 0 0 1 1 1 1 PCI domain DUF4817 PF16087.5 KFM62221.1 - 0.0059 16.4 0.1 0.026 14.3 0.1 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_23 PF13384.6 KFM62221.1 - 0.042 13.7 3.2 0.35 10.7 0.2 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_32 PF13565.6 KFM62221.1 - 0.12 13.0 0.9 0.71 10.5 0.0 2.5 2 1 1 3 3 3 0 Homeodomain-like domain API5 PF05918.11 KFM62222.1 - 1.8e-165 551.7 6.5 2.1e-165 551.5 6.5 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 KFM62222.1 - 0.0019 18.6 0.1 0.027 14.8 0.1 2.4 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.7 KFM62222.1 - 0.021 14.8 1.4 0.45 10.5 0.6 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KFM62222.1 - 0.14 12.4 1.2 0.31 11.2 0.2 2.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 BORCS6 PF10157.9 KFM62223.1 - 1.4e-56 191.0 2.1 1.4e-56 191.0 2.1 1.9 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 6 Laminin_II PF06009.12 KFM62223.1 - 0.014 15.4 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 Laminin Domain II YL1 PF05764.13 KFM62223.1 - 0.063 13.4 6.2 0.081 13.0 6.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Rhodanese PF00581.20 KFM62224.1 - 3.8e-12 46.7 0.0 7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain MFS_1 PF07690.16 KFM62225.1 - 4.7e-09 35.6 59.2 9e-05 21.6 24.4 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFM62226.1 - 2.8e-09 36.4 9.8 1.4e-08 34.1 9.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily S1FA PF04689.13 KFM62227.1 - 0.006 16.7 0.1 0.0087 16.2 0.1 1.2 1 0 0 1 1 1 1 DNA binding protein S1FA Bacillus_HBL PF05791.11 KFM62227.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3042 PF11240.8 KFM62227.1 - 0.88 9.6 5.8 0.41 10.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) Amnionless PF14828.6 KFM62227.1 - 1.1 8.0 6.4 0.072 11.9 0.4 1.9 1 1 0 2 2 2 0 Amnionless RhoGAP-FF1 PF16512.5 KFM62229.1 - 0.012 16.2 0.0 0.015 15.9 0.0 1.1 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain Integrase_H2C2 PF17921.1 KFM62230.1 - 1.8e-14 53.6 0.0 2.4e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM62230.1 - 0.0021 18.2 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 KFM62231.1 - 6e-07 29.2 0.1 1.5e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Actin PF00022.19 KFM62232.1 - 2.1e-30 105.6 0.0 2.6e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Actin Ldl_recept_b PF00058.17 KFM62234.1 - 9.2e-43 144.5 10.8 1.3e-14 54.3 0.3 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 KFM62234.1 - 1.5e-30 105.1 55.4 1e-12 48.1 10.2 4.8 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 KFM62234.1 - 1.1e-24 86.4 56.2 8.4e-11 42.0 9.0 4.7 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFM62234.1 - 2.4e-14 53.0 15.2 2.3e-07 30.6 2.5 4.7 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_CA PF07645.15 KFM62234.1 - 3e-07 30.5 8.2 3e-07 30.5 8.2 6.6 4 2 1 5 5 5 2 Calcium-binding EGF domain SGL PF08450.12 KFM62234.1 - 1.8e-05 24.5 1.2 1.3 8.6 0.2 3.4 2 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 KFM62234.1 - 0.0005 19.4 0.0 0.23 10.7 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF5050) Syndecan PF01034.20 KFM62234.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain EGF_3 PF12947.7 KFM62234.1 - 0.025 14.8 3.5 0.025 14.8 3.5 5.6 5 2 0 5 5 5 0 EGF domain BrkDBD PF09607.10 KFM62235.1 - 8.4e-08 31.9 0.1 1.5e-07 31.0 0.1 1.4 1 1 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_1 PF01527.20 KFM62235.1 - 0.00077 19.7 0.4 0.00086 19.6 0.4 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM62235.1 - 0.02 15.0 0.5 0.046 13.8 0.5 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain DUF572 PF04502.13 KFM62236.1 - 1.8e-88 297.3 20.9 5.4e-88 295.8 20.9 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF572) GFA PF04828.14 KFM62236.1 - 0.061 13.7 0.2 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KFM62236.1 - 0.081 13.0 0.6 0.22 11.6 0.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KFM62236.1 - 0.46 10.0 2.6 3 7.4 0.1 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding zf-FPG_IleRS PF06827.14 KFM62236.1 - 0.9 9.5 4.3 87 3.1 0.7 3.6 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Tho2 PF11262.8 KFM62236.1 - 1 8.5 9.1 2.1 7.5 9.1 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Rpr2 PF04032.16 KFM62236.1 - 1.4 9.3 4.7 0.44 10.9 0.8 2.2 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TMEM70 PF06979.12 KFM62237.1 - 0.00053 20.4 0.2 0.0011 19.4 0.2 1.6 1 1 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex DIM PF08194.12 KFM62239.1 - 0.23 11.7 1.4 0.73 10.1 1.4 1.9 1 0 0 1 1 1 0 DIM protein Dyp_perox PF04261.12 KFM62239.1 - 0.29 10.1 0.1 0.37 9.7 0.1 1.2 1 0 0 1 1 1 0 Dyp-type peroxidase family zf-RanBP PF00641.18 KFM62240.1 - 3.7e-10 38.9 6.3 5.1e-10 38.5 6.3 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KFM62240.1 - 3.7e-10 39.5 0.0 1.6e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM62240.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif CBM_19 PF03427.13 KFM62241.1 - 1.7 8.7 10.8 2.3 8.2 7.6 2.1 1 1 1 2 2 2 0 Carbohydrate binding domain (family 19) 7tm_1 PF00001.21 KFM62242.1 - 1.2e-07 31.4 5.3 1.4e-07 31.2 5.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HTH_Tnp_Tc3_2 PF01498.18 KFM62243.1 - 2.4e-16 59.7 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62243.1 - 9.6e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Activator-TraM PF11657.8 KFM62244.1 - 0.2 11.5 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM Aminotran_1_2 PF00155.21 KFM62245.1 - 1.2e-27 97.1 0.0 1.4e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFM62245.1 - 0.065 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PspB PF06667.12 KFM62245.1 - 0.069 13.2 0.3 0.19 11.8 0.3 1.7 1 0 0 1 1 1 0 Phage shock protein B FAM219A PF15260.6 KFM62246.1 - 3.2e-13 50.2 1.5 3.2e-13 50.2 1.5 1.8 2 0 0 2 2 2 1 Protein family FAM219A His_Phos_2 PF00328.22 KFM62247.1 - 3e-17 63.0 0.3 1.6e-08 34.3 0.0 2.7 2 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KFM62248.1 - 2.1e-24 86.6 0.2 2.5e-20 73.2 0.0 2.7 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) ETRAMP PF09716.10 KFM62248.1 - 9.5 6.4 7.1 89 3.3 4.2 3.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.25 KFM62249.1 - 7.2e-18 64.9 0.0 8.9e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KFM62250.1 - 8.6e-15 54.8 0.1 9.5e-15 54.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM62250.1 - 2.7e-09 36.7 0.1 3.3e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ALS_ss_C PF10369.9 KFM62250.1 - 0.024 14.9 0.2 1.1 9.6 0.1 2.5 1 1 1 2 2 2 0 Small subunit of acetolactate synthase DDE_3 PF13358.6 KFM62251.1 - 7.4e-16 58.2 0.1 1.8e-15 56.9 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62251.1 - 1.3e-10 41.3 1.0 2.6e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM62252.1 - 1.3e-16 60.6 3.0 2.3e-16 59.8 3.0 1.5 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM62252.1 - 1.6e-05 24.9 0.2 1.6e-05 24.9 0.2 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62252.1 - 0.001 18.8 1.8 0.025 14.4 0.1 2.8 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM62252.1 - 0.0083 15.7 0.4 0.047 13.3 0.0 2.4 3 1 1 4 4 4 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 KFM62252.1 - 0.016 15.8 2.4 0.016 15.8 2.4 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KFM62252.1 - 0.019 14.4 2.0 0.047 13.1 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc3_2 PF01498.18 KFM62253.1 - 6.2e-13 48.8 0.2 1.1e-12 48.0 0.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62253.1 - 5.6e-10 39.1 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM62253.1 - 3.3e-06 27.6 2.3 6.5e-06 26.7 2.3 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_3 PF01381.22 KFM62253.1 - 0.00053 20.0 0.7 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix MarR_2 PF12802.7 KFM62253.1 - 0.00065 19.5 0.3 0.06 13.2 0.0 2.4 2 0 0 2 2 2 1 MarR family PAX PF00292.18 KFM62253.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.6 KFM62253.1 - 0.0071 16.4 2.3 0.11 12.7 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM62253.1 - 0.014 15.4 1.8 0.055 13.5 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KFM62253.1 - 0.055 13.3 4.2 0.16 11.8 0.1 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_24 PF13412.6 KFM62253.1 - 0.07 12.7 2.0 1.1 8.9 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KFM62253.1 - 0.16 11.8 0.1 2.7 7.9 0.0 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB DDE_3 PF13358.6 KFM62254.1 - 4.8e-08 32.9 0.6 1.2e-07 31.6 0.7 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF5641 PF18701.1 KFM62254.1 - 9.3e-06 25.7 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Na_Ca_ex_C PF16494.5 KFM62255.1 - 4.2e-37 127.4 6.7 6.8e-37 126.8 6.7 1.3 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain Calx-beta PF03160.14 KFM62255.1 - 1e-31 109.0 1.2 1.7e-31 108.4 1.2 1.3 1 0 0 1 1 1 1 Calx-beta domain HTH_WhiA PF02650.14 KFM62255.1 - 0.23 11.8 1.4 0.32 11.4 0.2 1.9 2 0 0 2 2 2 0 WhiA C-terminal HTH domain HTH_Tnp_Tc3_2 PF01498.18 KFM62259.1 - 9.6e-16 57.8 6.5 1.8e-15 56.9 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62259.1 - 1.2e-15 57.5 0.1 1.2e-14 54.3 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM62259.1 - 0.00088 19.8 1.5 0.00088 19.8 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM62259.1 - 0.0019 17.9 0.1 0.067 13.0 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62259.1 - 0.0081 16.3 0.2 0.029 14.5 0.2 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM62259.1 - 0.028 14.4 2.2 0.034 14.2 0.3 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM62260.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62260.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Allexi_40kDa PF05549.11 KFM62261.1 - 0.011 15.3 2.6 0.022 14.3 2.6 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2407_C PF13373.6 KFM62261.1 - 0.012 15.8 1.3 0.03 14.5 1.3 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain VGPC1_C PF16799.5 KFM62261.1 - 0.019 15.0 3.7 0.035 14.1 0.2 2.7 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 PKcGMP_CC PF16808.5 KFM62261.1 - 0.13 12.1 0.3 0.13 12.1 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GREB1 PF15782.5 KFM62261.1 - 3.3 4.7 15.8 3.6 4.6 15.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Cluap1 PF10234.9 KFM62262.1 - 0.55 9.6 16.5 0.44 9.9 4.3 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 TMF_TATA_bd PF12325.8 KFM62262.1 - 9.5 6.5 22.2 0.18 12.1 5.1 3.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Ank_4 PF13637.6 KFM62264.1 - 7.7e-146 472.8 71.7 1.6e-13 50.8 0.4 16.0 2 2 19 22 22 22 21 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM62264.1 - 3.3e-144 469.8 50.9 3.1e-17 62.9 1.4 12.4 1 1 12 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.30 KFM62264.1 - 7e-136 437.4 71.4 3.1e-07 30.5 0.0 23.2 23 0 0 23 23 23 21 Ankyrin repeat Ank_5 PF13857.6 KFM62264.1 - 6.5e-123 399.2 44.2 2.5e-13 49.9 0.0 16.2 5 4 11 17 17 17 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM62264.1 - 7.7e-118 370.0 43.2 2.8e-06 27.2 0.1 23.5 24 0 0 24 24 24 20 Ankyrin repeat UPA_2 PF17809.1 KFM62264.1 - 7.8e-56 187.5 0.0 1.7e-55 186.4 0.0 1.6 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFM62264.1 - 1.7e-35 121.2 1.6 1.6e-27 95.7 0.0 3.1 3 0 0 3 3 3 2 ZU5 domain Death PF00531.22 KFM62264.1 - 2.6e-15 56.3 0.3 6.2e-15 55.1 0.3 1.7 1 0 0 1 1 1 1 Death domain PK_C PF02887.16 KFM62264.1 - 0.0017 18.6 2.6 14 5.9 0.0 4.5 4 1 0 4 4 4 2 Pyruvate kinase, alpha/beta domain Rieske_3 PF18465.1 KFM62265.1 - 0.003 17.8 0.0 0.0037 17.5 0.0 1.1 1 0 0 1 1 1 1 Rieske 3Fe-4S zf-C2H2 PF00096.26 KFM62266.1 - 3.2e-67 219.4 116.0 8.5e-07 29.1 3.1 13.2 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM62266.1 - 1.4e-55 183.3 94.4 4.5e-10 39.5 0.2 13.6 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM62266.1 - 1.3e-49 162.5 105.9 0.00031 21.3 1.4 13.3 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM62266.1 - 4.2e-31 106.4 89.3 0.001 19.4 0.5 13.2 13 0 0 13 13 13 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM62266.1 - 2.7e-22 78.5 79.7 0.0024 18.1 0.3 13.1 12 1 1 13 13 13 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM62266.1 - 1.2e-18 66.6 100.3 3.9e-05 23.5 1.5 13.5 13 0 0 13 13 13 9 C2H2-type zinc finger FYVE PF01363.21 KFM62266.1 - 0.023 14.8 74.9 1 9.6 5.6 7.6 1 1 5 6 6 6 0 FYVE zinc finger zf-C2HC_2 PF13913.6 KFM62266.1 - 0.055 13.4 70.0 0.38 10.7 0.1 12.5 12 1 1 13 13 13 0 zinc-finger of a C2HC-type DUF3268 PF11672.8 KFM62266.1 - 0.056 13.8 37.7 1.4 9.3 1.8 5.9 4 1 0 5 5 5 0 zinc-finger-containing domain NOG1 PF06858.14 KFM62266.1 - 0.091 12.6 0.0 0.9 9.4 0.0 2.6 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) zf-C2H2_3rep PF18868.1 KFM62266.1 - 1.4 9.6 60.8 0.17 12.6 13.6 8.1 4 3 0 6 6 6 0 Zinc finger C2H2-type, 3 repeats DDE_Tnp_4 PF13359.6 KFM62267.1 - 0.0008 19.1 0.0 0.00091 18.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 KFM62268.1 - 0.0073 16.0 0.4 0.021 14.5 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Herpes_glycoH_C PF17488.2 KFM62269.1 - 0.012 15.4 0.7 0.015 15.1 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM62270.1 - 5.3e-16 58.6 3.5 6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62270.1 - 1.3e-13 51.0 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62270.1 - 1.9e-07 30.7 1.2 7.3e-07 28.8 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62270.1 - 0.0029 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62270.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain CRM1_C PF08767.11 KFM62271.1 - 8.6e-130 432.6 8.0 1.4e-129 431.8 2.2 2.8 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KFM62271.1 - 6.7e-42 143.1 6.0 6.7e-42 143.1 6.0 5.1 7 1 0 7 7 7 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KFM62271.1 - 1.8e-35 120.4 3.6 1.9e-35 120.3 1.5 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KFM62271.1 - 1.6e-30 105.0 2.5 2e-30 104.6 0.7 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KFM62271.1 - 1e-18 66.5 2.2 2.4e-18 65.4 2.2 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KFM62271.1 - 1.8e-12 47.0 0.1 7.1e-12 45.1 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Sec7_N PF12783.7 KFM62271.1 - 0.0024 17.8 9.5 0.08 12.9 0.0 4.6 4 1 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.7 KFM62271.1 - 0.44 11.2 4.7 5.1 7.8 0.1 4.8 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region Methyltransf_11 PF08241.12 KFM62273.1 - 3.3e-18 66.1 0.0 6.5e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM62273.1 - 1.3e-14 54.6 0.0 4.5e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM62273.1 - 1.8e-11 44.0 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM62273.1 - 1e-07 32.6 0.0 2.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM62273.1 - 6.8e-06 25.6 0.0 9.9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFM62273.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM62273.1 - 0.0004 20.0 0.0 0.00081 19.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 KFM62273.1 - 0.0042 17.0 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 KFM62273.1 - 0.0045 17.0 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KFM62273.1 - 0.026 14.9 0.0 0.066 13.6 0.0 1.8 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF1541 PF07563.11 KFM62273.1 - 0.034 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) DREV PF05219.12 KFM62273.1 - 0.041 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 KFM62273.1 - 0.058 13.1 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KFM62273.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KFM62273.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 KFM62273.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CIMR PF00878.18 KFM62274.1 - 2e-18 66.8 4.0 1.1e-14 54.7 0.5 2.0 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KFM62274.1 - 2.2e-05 24.4 0.5 0.072 12.9 0.0 2.0 1 1 1 2 2 2 2 Autophagy-related protein 27 PRKCSH_1 PF13015.6 KFM62274.1 - 0.00041 20.1 0.1 0.00057 19.6 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Sulfotransfer_3 PF13469.6 KFM62276.1 - 3.2e-11 44.0 0.0 7.3e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family AbiEi_3_N PF17194.4 KFM62276.1 - 0.043 13.8 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM62277.1 - 3.3e-13 49.7 3.3 8.9e-13 48.3 3.3 1.7 1 0 0 1 1 1 1 Transposase Sulfotransfer_3 PF13469.6 KFM62277.1 - 2.3e-11 44.5 0.0 8.4e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family HTH_23 PF13384.6 KFM62277.1 - 0.002 17.9 0.0 0.0085 15.9 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain Sulfotransfer_1 PF00685.27 KFM62277.1 - 0.0032 17.0 0.2 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase domain HTH_38 PF13936.6 KFM62277.1 - 0.0074 16.0 0.6 0.14 11.9 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM62277.1 - 0.028 14.3 0.0 0.096 12.6 0.0 2.0 1 0 0 1 1 1 0 Tc3 transposase Lyase_1 PF00206.20 KFM62279.1 - 7.1e-85 285.1 0.0 3.5e-84 282.8 0.0 2.0 2 1 0 2 2 2 1 Lyase ASL_C2 PF14698.6 KFM62279.1 - 9.9e-22 77.5 0.0 2.4e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DNA_pol_B_2 PF03175.13 KFM62281.1 - 1.4e-15 57.2 0.3 8.6e-07 28.2 0.1 2.1 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DDE_Tnp_4 PF13359.6 KFM62282.1 - 1.9e-32 112.1 0.0 2.7e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM62282.1 - 5.9e-11 42.3 0.0 2.7e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFM62282.1 - 0.011 15.3 0.1 0.8 9.3 0.1 2.2 1 1 0 1 1 1 0 Transposase DDE domain DUF4371 PF14291.6 KFM62283.1 - 2.3e-10 40.6 0.0 3.5e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Annexin PF00191.20 KFM62285.1 - 0.024 14.7 0.0 0.069 13.2 0.0 1.8 1 0 0 1 1 1 0 Annexin IL4 PF00727.18 KFM62285.1 - 0.23 11.7 1.8 0.42 10.9 1.1 1.9 1 1 0 1 1 1 0 Interleukin 4 Nop14 PF04147.12 KFM62285.1 - 0.52 8.4 34.9 0.8 7.8 34.9 1.2 1 0 0 1 1 1 0 Nop14-like family DSL PF01414.19 KFM62286.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Delta serrate ligand EGF PF00008.27 KFM62287.1 - 9.6e-07 29.0 7.5 9.6e-07 29.0 7.5 2.6 2 0 0 2 2 2 2 EGF-like domain Katanin_con80 PF13925.6 KFM62287.1 - 0.15 12.1 0.1 0.19 11.8 0.1 1.1 1 0 0 1 1 1 0 con80 domain of Katanin DDE_Tnp_1_7 PF13843.6 KFM62288.1 - 7.3e-51 173.5 0.1 1.3e-32 113.5 0.0 2.0 1 1 1 2 2 2 2 Transposase IS4 DDE_3 PF13358.6 KFM62291.1 - 0.0059 16.4 0.0 0.0068 16.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease EGF PF00008.27 KFM62292.1 - 8e-49 163.5 116.7 1.9e-07 31.2 6.4 10.3 10 0 0 10 10 10 9 EGF-like domain EGF_2 PF07974.13 KFM62292.1 - 2.1e-11 44.0 143.4 0.078 13.4 7.3 10.4 10 0 0 10 10 10 9 EGF-like domain hEGF PF12661.7 KFM62292.1 - 0.056 14.1 7.2 0.056 14.1 7.2 11.3 10 1 0 10 10 10 0 Human growth factor-like EGF hEGF PF12661.7 KFM62293.1 - 0.00076 20.0 18.8 0.084 13.5 6.8 3.7 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.13 KFM62293.1 - 0.026 14.9 24.0 0.18 12.2 8.4 3.0 2 0 0 2 2 2 0 EGF-like domain EGF PF00008.27 KFM62293.1 - 0.31 11.4 27.0 0.38 11.1 8.1 3.1 3 1 0 3 3 3 0 EGF-like domain Metallothio_Euk PF12749.7 KFM62293.1 - 2.1 8.5 31.2 20 5.4 8.5 2.3 1 1 1 2 2 2 0 Eukaryotic metallothionein Toxin_7 PF05980.12 KFM62294.1 - 0.038 14.2 3.6 0.085 13.1 3.6 1.6 1 1 0 1 1 1 0 Toxin 7 Conotoxin PF02950.17 KFM62294.1 - 0.22 12.5 2.6 0.33 12.0 2.6 1.2 1 0 0 1 1 1 0 Conotoxin LPMO_10 PF03067.15 KFM62296.1 - 1.4e-29 104.2 0.0 1.7e-29 103.9 0.0 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DIRP PF06584.13 KFM62297.1 - 1.4e-41 141.0 0.9 2.8e-41 140.0 0.2 1.9 2 0 0 2 2 2 1 DIRP Mod_r PF07200.13 KFM62297.1 - 0.26 11.4 4.0 0.51 10.4 3.6 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Ras PF00071.22 KFM62298.1 - 5.4e-58 195.2 0.1 6.5e-58 194.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM62298.1 - 4.7e-32 110.7 0.0 6.7e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM62298.1 - 5.3e-15 55.3 0.0 7.2e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM62298.1 - 6e-05 22.5 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM62298.1 - 7e-05 22.5 0.0 0.0025 17.4 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM62298.1 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM62298.1 - 0.002 18.1 0.1 0.78 9.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KFM62298.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KFM62298.1 - 0.016 15.0 0.0 1.4 8.6 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KFM62298.1 - 0.039 13.4 0.0 0.062 12.7 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KFM62298.1 - 0.079 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 KFM62298.1 - 0.092 13.1 0.1 0.13 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 KFM62298.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KFM62298.1 - 0.14 12.4 0.1 0.55 10.5 0.1 2.0 1 1 1 2 2 2 0 AAA domain UDPGP PF01704.18 KFM62299.1 - 5.5e-86 288.8 0.0 7.1e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF327 PF03885.13 KFM62299.1 - 0.037 14.0 1.4 0.062 13.3 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF327) UDPGP PF01704.18 KFM62300.1 - 9.2e-90 301.2 0.1 1e-89 301.0 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase FG-GAP_2 PF14312.6 KFM62300.1 - 0.15 12.3 0.2 0.3 11.4 0.2 1.4 1 0 0 1 1 1 0 FG-GAP repeat HTH_Tnp_Tc3_2 PF01498.18 KFM62301.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62301.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62301.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62301.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62301.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62302.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62302.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62302.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62302.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62302.1 - 1.8 9.2 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62303.1 - 4.7e-16 58.8 3.5 5.6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62303.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62303.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62303.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62303.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM62304.1 - 1.1e-30 107.1 0.1 1.3e-30 106.9 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 HTH_Tnp_Tc3_2 PF01498.18 KFM62305.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62305.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62305.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62305.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62305.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain SAYSvFN PF10260.9 KFM62307.1 - 0.042 13.8 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) HTH_Tnp_Tc3_2 PF01498.18 KFM62309.1 - 4.4e-22 78.1 3.0 6.4e-22 77.6 2.2 1.7 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM62309.1 - 0.00012 22.7 6.9 0.00031 21.3 0.3 3.1 3 1 0 3 3 3 1 Homeodomain-like domain HTH_12 PF08461.10 KFM62309.1 - 0.0019 18.1 0.1 0.0044 16.9 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain PAX PF00292.18 KFM62309.1 - 0.022 14.7 0.2 0.1 12.5 0.1 1.9 1 1 1 2 2 2 0 'Paired box' domain HTH_21 PF13276.6 KFM62309.1 - 0.033 14.3 0.4 0.11 12.6 0.3 2.0 2 0 0 2 2 2 0 HTH-like domain Fasciclin PF02469.22 KFM62310.1 - 4.3e-42 143.4 0.0 8.7e-19 68.0 0.0 3.0 3 0 0 3 3 3 3 Fasciclin domain DUF211 PF02680.14 KFM62310.1 - 0.0098 16.0 0.7 6.3 7.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized ArCR, COG1888 PSRP-3_Ycf65 PF04839.13 KFM62310.1 - 0.16 12.2 0.1 0.52 10.6 0.1 1.8 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Forkhead PF00250.18 KFM62312.1 - 7.7e-16 58.1 0.0 1.3e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Neugrin PF06413.11 KFM62312.1 - 0.14 12.2 2.6 0.28 11.1 2.7 1.5 1 1 0 1 1 1 0 Neugrin LIX1 PF14954.6 KFM62313.1 - 2.2e-15 56.6 0.0 2.3e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Limb expression 1 HTH_Tnp_Tc3_2 PF01498.18 KFM62314.1 - 1.9e-16 60.1 2.2 4.2e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62314.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Neur_chan_memb PF02932.16 KFM62315.1 - 1.1e-80 271.2 0.1 1.6e-80 270.6 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM62315.1 - 3.8e-15 55.9 0.0 5.2e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Prominin PF05478.11 KFM62315.1 - 0.065 11.2 0.0 0.11 10.5 0.0 1.3 1 0 0 1 1 1 0 Prominin PAC1 PF16094.5 KFM62316.1 - 4.5e-24 85.1 15.4 5.2e-21 75.1 15.4 2.0 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 BDHCT_assoc PF16204.5 KFM62316.1 - 0.086 12.5 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein EF1G PF00647.19 KFM62317.1 - 7.2e-50 167.5 1.6 1.3e-49 166.7 1.6 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain AP3D1 PF06375.11 KFM62317.1 - 0.62 10.3 15.9 1 9.6 15.9 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 PPL5 PF18168.1 KFM62317.1 - 2.3 7.4 5.9 2.8 7.2 5.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_M16_C PF05193.21 KFM62317.1 - 2.5 8.1 6.3 4.1 7.4 6.3 1.5 1 1 0 1 1 1 0 Peptidase M16 inactive domain Peptidase_M49 PF03571.15 KFM62318.1 - 5.3e-152 507.0 0.0 5.9e-152 506.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 ACP PF06857.11 KFM62320.1 - 0.035 14.3 0.0 0.048 13.9 0.0 1.3 1 1 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) HrcA_DNA-bdg PF03444.15 KFM62320.1 - 0.053 13.2 0.2 0.066 12.9 0.2 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding LRR_8 PF13855.6 KFM62321.1 - 7.2e-11 41.7 4.5 0.00013 21.7 0.1 3.9 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KFM62321.1 - 0.00019 21.8 7.5 0.00095 19.5 0.6 4.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM62321.1 - 0.0012 18.4 0.9 0.0029 17.1 0.7 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.6 KFM62321.1 - 0.0037 17.2 0.0 0.032 14.2 0.0 2.5 2 2 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFM62321.1 - 0.068 13.2 0.4 10 6.5 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 KFM62321.1 - 0.27 11.9 7.5 3.4 8.6 0.1 4.4 5 1 0 5 5 5 0 Leucine Rich Repeat DDE_3 PF13358.6 KFM62322.1 - 0.00064 19.5 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease MurJ PF03023.14 KFM62323.1 - 0.064 11.8 0.0 0.074 11.6 0.0 1.0 1 0 0 1 1 1 0 Lipid II flippase MurJ Calx-beta PF03160.14 KFM62324.1 - 6.6e-10 39.1 0.1 1.2e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 Calx-beta domain Amido_AtzD_TrzD PF09663.10 KFM62324.1 - 0.15 11.1 0.1 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) EF-hand_1 PF00036.32 KFM62325.1 - 1.8e-06 27.0 0.2 2.6e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFM62325.1 - 6.1e-06 26.6 0.3 7e-06 26.4 0.3 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM62325.1 - 6.4e-06 25.4 0.3 9.3e-06 24.9 0.3 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFM62325.1 - 0.00017 21.2 0.3 0.0003 20.5 0.3 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KFM62325.1 - 0.013 15.3 0.2 0.02 14.7 0.2 1.4 1 1 0 1 1 1 0 EF-hand domain pair Prenyltrans PF00432.21 KFM62326.1 - 4.3e-28 96.7 6.8 3.8e-09 36.1 0.1 5.5 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Triabin PF03973.13 KFM62330.1 - 0.016 15.1 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 Triabin G-alpha PF00503.20 KFM62331.1 - 6.1e-34 117.7 0.0 6.8e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFM62331.1 - 0.023 14.1 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family DDE_3 PF13358.6 KFM62332.1 - 1.8e-10 40.7 0.0 3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62332.1 - 0.0014 18.8 1.4 0.0056 16.9 0.5 2.3 2 0 0 2 2 2 1 Transposase bZIP_2 PF07716.15 KFM62333.1 - 1.1e-14 54.2 15.3 2.5e-14 53.1 15.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM62333.1 - 0.0002 21.4 14.8 0.00022 21.3 13.0 2.0 2 1 1 3 3 3 1 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 KFM62333.1 - 0.013 15.7 6.8 0.015 15.5 6.8 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Herpes_UL6 PF01763.16 KFM62333.1 - 0.023 13.2 3.2 0.025 13.1 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Tox-ODYAM1 PF15642.6 KFM62333.1 - 0.027 13.5 2.9 0.03 13.3 2.9 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Seryl_tRNA_N PF02403.22 KFM62333.1 - 1.1 9.6 10.3 2 8.7 10.3 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 KFM62333.1 - 1.4 9.4 5.9 3.6 8.1 4.0 2.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 KFM62333.1 - 1.5 9.1 6.7 0.56 10.4 3.5 1.9 1 1 2 3 3 3 0 Haemolysin XhlA TMF_DNA_bd PF12329.8 KFM62333.1 - 1.5 8.9 14.5 9.5 6.3 13.5 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KFM62333.1 - 2.1 8.2 9.3 0.49 10.2 3.6 2.4 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 KFM62334.1 - 7.8e-16 57.9 15.2 7.8e-16 57.9 15.2 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM62334.1 - 1.4e-05 25.1 12.7 3e-05 24.0 12.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor Csm1_N PF18504.1 KFM62334.1 - 0.022 15.1 1.1 0.063 13.6 1.1 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain SR-25 PF10500.9 KFM62334.1 - 0.13 11.8 14.0 0.24 11.0 14.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IBB PF01749.20 KFM62334.1 - 0.36 11.3 12.8 0.061 13.8 9.1 1.7 2 0 0 2 2 2 0 Importin beta binding domain bZIP_Maf PF03131.17 KFM62334.1 - 2.3 8.8 14.1 0.16 12.5 7.9 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor HTH_Tnp_Tc3_2 PF01498.18 KFM62335.1 - 3.9e-16 59.1 3.0 6.2e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62335.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62335.1 - 3.2e-07 30.0 1.6 7.6e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62335.1 - 0.0029 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62335.1 - 0.03 14.4 0.4 0.097 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM62335.1 - 2.8 8.6 15.6 0.13 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62336.1 - 2.1e-16 59.9 2.6 3.9e-16 59.0 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62336.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4817 PF16087.5 KFM62338.1 - 1e-10 41.3 0.2 1e-10 41.3 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 KFM62338.1 - 0.00045 20.8 0.2 0.0012 19.4 0.2 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Rhomboid_N PF12122.8 KFM62338.1 - 0.039 14.1 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease HTH_Tnp_Tc3_2 PF01498.18 KFM62339.1 - 8.6e-16 58.0 6.5 1.5e-15 57.2 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62339.1 - 8.9e-16 58.0 0.1 1.4e-14 54.1 0.0 2.4 1 1 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM62339.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM62339.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62339.1 - 0.016 15.3 0.1 0.065 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM62339.1 - 0.03 14.3 2.6 0.035 14.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix DUF4503 PF14951.6 KFM62340.1 - 1e-18 67.0 3.3 1.1e-18 66.9 3.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) CDC24_OB3 PF17244.2 KFM62340.1 - 0.049 13.3 3.2 0.14 11.8 3.2 1.7 1 1 0 1 1 1 0 Cell division control protein 24, OB domain 3 zf-RRPl_C4 PF17026.5 KFM62340.1 - 0.061 13.4 4.8 0.099 12.8 4.8 1.7 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type SIX1_SD PF16878.5 KFM62344.1 - 2.5e-49 166.4 0.7 4.5e-49 165.6 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFM62344.1 - 7.1e-15 54.6 0.7 2.9e-14 52.7 0.3 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFM62344.1 - 2.9e-12 46.3 1.0 6e-12 45.3 1.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFM62344.1 - 0.023 14.2 0.1 0.054 13.0 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 KFM62344.1 - 0.033 14.3 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix ANAPC3 PF12895.7 KFM62344.1 - 0.12 12.6 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 HTH_Tnp_Tc3_2 PF01498.18 KFM62345.1 - 2e-17 63.2 1.4 4.2e-17 62.2 1.4 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62345.1 - 5.8e-13 48.8 0.0 9.8e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM62345.1 - 2.2e-06 28.2 5.6 2.9e-05 24.6 1.8 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM62345.1 - 0.0011 19.0 0.7 0.033 14.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix MarR_2 PF12802.7 KFM62345.1 - 0.0058 16.5 0.4 0.38 10.7 0.0 2.5 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM62345.1 - 0.0076 16.2 1.2 0.04 13.9 0.0 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM62345.1 - 0.021 15.0 1.6 0.55 10.4 0.1 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM62345.1 - 0.027 14.3 0.8 1.2 9.1 0.0 3.0 2 0 0 2 2 2 0 Homeodomain-like domain PAX PF00292.18 KFM62345.1 - 0.039 13.9 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain DUF5438 PF17506.2 KFM62345.1 - 0.056 13.8 0.3 0.13 12.6 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5438) HTH_24 PF13412.6 KFM62345.1 - 0.18 11.4 1.2 3.1 7.4 0.0 2.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 KFM62345.1 - 0.3 11.6 1.0 18 5.9 0.2 2.7 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain Actin PF00022.19 KFM62346.1 - 3.1e-91 306.0 0.0 7.2e-59 199.4 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KFM62346.1 - 0.0032 16.4 0.0 0.77 8.5 0.0 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KFM62346.1 - 0.02 15.3 0.0 0.079 13.4 0.0 2.1 2 1 0 2 2 2 0 Cell division protein FtsA Robl_LC7 PF03259.17 KFM62346.1 - 0.2 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain Endostatin PF06482.11 KFM62347.1 - 1.8e-08 34.2 0.3 2.6e-08 33.7 0.3 1.3 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Vpu PF00558.19 KFM62347.1 - 0.12 12.1 1.5 0.17 11.7 1.5 1.2 1 0 0 1 1 1 0 Vpu protein Endostatin PF06482.11 KFM62348.1 - 1.6e-43 149.4 0.1 9.8e-35 120.5 0.0 2.3 2 1 1 3 3 3 2 Collagenase NC10 and Endostatin Collagen PF01391.18 KFM62348.1 - 4.2e-41 138.5 218.1 4.2e-10 39.2 26.1 9.3 5 3 3 8 8 8 7 Collagen triple helix repeat (20 copies) DUF1554 PF07588.11 KFM62348.1 - 0.29 10.9 0.0 0.45 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) MADF_DNA_bdg PF10545.9 KFM62349.1 - 1.6e-16 60.4 1.1 1.6e-16 60.4 1.1 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BBS2_N PF14781.6 KFM62349.1 - 0.018 15.0 0.1 6.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal DUF659 PF04937.15 KFM62351.1 - 2.8e-05 24.0 0.9 6.3e-05 22.9 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) AHD PF17793.1 KFM62352.1 - 0.03 14.1 0.6 2.4 8.0 0.0 2.8 2 1 1 3 3 3 0 ANC1 homology domain (AHD) HTH_23 PF13384.6 KFM62353.1 - 0.013 15.3 0.2 0.056 13.3 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_IclR PF09339.10 KFM62353.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 KFM62353.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DDE_3 PF13358.6 KFM62354.1 - 0.098 12.4 0.2 0.17 11.7 0.1 1.5 1 1 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.6 KFM62355.1 - 0.068 12.9 0.1 0.081 12.7 0.1 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM62356.1 - 6e-207 661.9 265.0 9e-10 38.5 0.9 39.4 40 0 0 40 40 39 35 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62356.1 - 1.8e-146 469.0 309.9 1.9e-05 24.8 2.0 37.9 38 0 0 38 38 38 36 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62356.1 - 4.1e-95 304.1 303.3 0.0021 18.8 1.8 37.8 38 0 0 38 38 38 35 C2H2-type zinc finger zf-met PF12874.7 KFM62356.1 - 9.9e-58 191.0 288.5 0.00031 21.0 0.7 36.0 36 0 0 36 36 36 31 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM62356.1 - 3.7e-45 151.1 260.4 0.00052 19.9 0.3 36.2 36 0 0 36 36 36 29 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM62356.1 - 2.6e-43 145.5 227.7 0.011 16.0 0.1 36.3 35 1 1 36 36 36 24 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM62356.1 - 5.5e-10 39.4 60.5 0.27 11.5 0.2 17.9 7 5 11 19 19 19 5 BolA-like protein Tox-HNH-HHH PF15637.6 KFM62356.1 - 0.0041 17.3 16.9 30 4.8 0.0 9.2 6 3 5 12 12 12 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF1263 PF06882.12 KFM62356.1 - 0.0065 16.5 0.6 13 5.9 0.0 5.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1263) zf-H2C2_5 PF13909.6 KFM62356.1 - 0.16 11.7 220.9 0.18 11.6 0.2 33.2 35 0 0 35 35 35 0 C2H2-type zinc-finger domain GAGA PF09237.11 KFM62356.1 - 3.6 7.5 56.6 1.3 8.8 0.0 14.7 12 4 4 17 17 17 0 GAGA factor Exo_endo_phos PF03372.23 KFM62360.1 - 0.00044 19.8 0.0 0.00077 19.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNA_binding PF01877.17 KFM62361.1 - 0.06 13.6 0.6 0.23 11.7 0.2 1.9 2 0 0 2 2 2 0 RNA binding DDE_3 PF13358.6 KFM62362.1 - 0.037 13.8 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Pkinase PF00069.25 KFM62363.1 - 3.2e-71 239.8 0.0 5.3e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM62363.1 - 6.6e-34 117.4 0.0 9.9e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFM62363.1 - 4.8e-29 100.0 20.4 2.1e-15 56.3 7.5 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFM62363.1 - 9.2e-09 35.0 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C1_2 PF03107.16 KFM62363.1 - 1.5e-07 31.6 12.7 0.00035 20.8 1.9 2.5 2 0 0 2 2 2 2 C1 domain PH PF00169.29 KFM62363.1 - 3.4e-07 30.7 0.3 6.6e-07 29.8 0.3 1.5 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 KFM62363.1 - 0.00012 21.5 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.29 KFM62363.1 - 0.0035 17.2 17.5 0.051 13.5 5.8 2.5 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.11 KFM62363.1 - 0.0065 16.8 16.2 0.11 12.8 4.2 2.6 2 0 0 2 2 2 2 RING-like domain RIO1 PF01163.22 KFM62363.1 - 0.0066 16.1 0.5 0.017 14.7 0.1 1.8 2 0 0 2 2 2 1 RIO1 family zf-RING_9 PF13901.6 KFM62363.1 - 0.0098 15.9 15.4 0.099 12.6 3.3 2.6 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon FYVE_2 PF02318.16 KFM62363.1 - 0.015 15.5 2.5 0.015 15.5 2.5 2.8 3 0 0 3 3 2 0 FYVE-type zinc finger APH PF01636.23 KFM62363.1 - 0.075 12.9 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1204 PF06721.11 KFM62363.1 - 0.31 10.5 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) Prok-RING_1 PF14446.6 KFM62363.1 - 0.73 9.8 13.6 0.77 9.7 1.6 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KFM62363.1 - 2.2 7.9 16.7 0.74 9.4 1.4 3.0 3 0 0 3 3 3 0 PHD-finger Pecanex_C PF05041.15 KFM62364.1 - 1.8e-116 387.6 0.0 2.2e-116 387.3 0.0 1.1 1 0 0 1 1 1 1 Pecanex protein (C-terminus) NKAIN PF05640.14 KFM62367.1 - 0.12 11.6 5.5 0.17 11.1 5.5 1.2 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein Pkinase_Tyr PF07714.17 KFM62370.1 - 4.3e-68 229.4 0.0 6.2e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM62370.1 - 1.3e-61 208.3 0.0 2.3e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 KFM62370.1 - 2.2e-13 49.6 0.2 4.9e-13 48.5 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM62370.1 - 9.2e-12 44.6 0.1 1.9e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM62370.1 - 6.4e-09 35.4 0.1 1.4e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arteri_nucleo PF01481.16 KFM62370.1 - 0.17 12.2 1.2 0.34 11.2 0.7 1.7 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein DUF3552 PF12072.8 KFM62370.1 - 1.3 8.4 13.2 2.4 7.5 13.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) MoaC PF01967.21 KFM62371.1 - 4e-17 62.6 0.1 4.5e-17 62.4 0.1 1.0 1 0 0 1 1 1 1 MoaC family HTH_23 PF13384.6 KFM62372.1 - 6.9e-06 25.7 1.0 6.4e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62372.1 - 1.3e-05 25.2 0.1 7e-05 22.9 0.0 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM62372.1 - 1.9e-05 24.6 0.1 0.0041 17.2 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM62372.1 - 0.00055 20.5 1.9 0.00097 19.7 1.9 1.4 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM62372.1 - 0.00094 18.8 0.1 0.0037 16.8 0.0 1.9 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR_2 PF12802.7 KFM62372.1 - 0.0012 18.7 0.3 0.0056 16.5 0.0 2.0 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 KFM62372.1 - 0.0018 18.0 0.0 0.0045 16.7 0.0 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_6 PF01418.17 KFM62372.1 - 0.0074 16.2 0.0 0.015 15.3 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family Tox-REase-7 PF15649.6 KFM62372.1 - 0.038 14.3 0.1 0.048 14.0 0.1 1.3 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 7 HTH_5 PF01022.20 KFM62372.1 - 0.1 12.5 0.7 0.2 11.5 0.0 1.8 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family zf-C2H2 PF00096.26 KFM62373.1 - 3.9e-18 64.8 36.3 5.5e-05 23.4 1.4 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62373.1 - 3.4e-13 49.2 31.9 0.0018 19.0 1.6 4.8 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM62373.1 - 4.3e-08 33.2 28.0 1.2e-05 25.5 1.5 5.2 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFM62373.1 - 0.00018 21.4 27.5 0.038 14.0 2.3 4.8 4 1 1 5 5 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFM62373.1 - 0.00044 20.5 15.3 0.023 15.0 4.0 3.2 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Actin_micro PF17003.5 KFM62373.1 - 0.0022 17.2 6.7 0.02 14.1 0.5 2.8 1 1 1 2 2 2 1 Putative actin-like family zf-C2H2_jaz PF12171.8 KFM62373.1 - 0.0032 17.7 17.8 1.1 9.6 2.3 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding LIM PF00412.22 KFM62373.1 - 0.0059 16.8 2.2 0.0059 16.8 2.2 2.6 2 0 0 2 2 2 1 LIM domain C1_4 PF07975.12 KFM62373.1 - 0.0087 16.3 11.1 0.02 15.1 1.2 2.7 2 1 0 2 2 2 1 TFIIH C1-like domain zf-C2H2_3rep PF18868.1 KFM62373.1 - 0.0096 16.6 11.6 0.88 10.2 0.5 4.0 1 1 3 4 4 4 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KFM62373.1 - 0.027 14.8 18.2 0.092 13.2 1.9 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type CpXC PF14353.6 KFM62373.1 - 0.041 13.9 8.3 1.1 9.3 0.1 3.5 1 1 2 3 3 3 0 CpXC protein zf-C2H2_11 PF16622.5 KFM62373.1 - 0.057 13.2 18.5 0.71 9.7 0.3 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type DUF2256 PF10013.9 KFM62373.1 - 0.2 11.8 7.6 0.73 10.0 0.0 3.5 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_ZIC PF18366.1 KFM62373.1 - 0.22 11.6 4.2 4.4 7.5 0.3 3.0 2 0 0 2 2 2 0 Zic proteins zinc finger domain Lar_restr_allev PF14354.6 KFM62373.1 - 0.25 11.7 4.7 0.36 11.2 0.3 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-C2H2_9 PF16293.5 KFM62373.1 - 0.35 10.8 6.1 41 4.1 0.0 4.0 2 2 2 4 4 4 0 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM62373.1 - 0.36 11.1 4.1 0.62 10.4 0.7 2.6 1 1 2 3 3 3 0 BolA-like protein GAGA PF09237.11 KFM62373.1 - 0.49 10.3 2.8 21 5.0 0.4 3.1 1 1 2 3 3 3 0 GAGA factor Prok-RING_1 PF14446.6 KFM62373.1 - 0.51 10.3 7.4 35 4.4 0.0 4.1 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 Yippee-Mis18 PF03226.14 KFM62373.1 - 0.57 10.4 5.5 1.1 9.5 4.8 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2180 PF09947.9 KFM62373.1 - 0.61 10.1 3.6 3.3 7.8 3.6 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) zf_UBZ PF18439.1 KFM62373.1 - 0.74 9.5 10.6 4.1 7.1 0.3 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 KFM62373.1 - 1.4 9.0 11.4 0.23 11.5 2.2 3.0 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf_C2H2_ZHX PF18387.1 KFM62373.1 - 1.4 8.6 17.1 3.3 7.4 0.1 4.2 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_15 PF17032.5 KFM62373.1 - 1.7 9.4 8.9 2.9e+02 2.3 8.9 2.9 1 1 0 1 1 1 0 zinc-ribbon family zf-C2H2_3 PF13878.6 KFM62373.1 - 1.8 8.4 15.4 1.6 8.6 3.4 4.0 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO Zn-ribbon_8 PF09723.10 KFM62373.1 - 3.5 7.8 11.1 19 5.5 0.0 3.7 2 1 2 4 4 4 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 KFM62373.1 - 4.4 7.3 11.7 1.8e+03 -1.0 10.6 3.3 2 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.6 KFM62373.1 - 7.4 6.6 9.5 29 4.7 0.5 3.6 2 2 1 3 3 3 0 zinc-ribbon domain RIG-I_C-RD PF11648.8 KFM62373.1 - 8.8 6.6 9.4 39 4.5 0.4 3.3 2 1 1 3 3 3 0 C-terminal domain of RIG-I rve PF00665.26 KFM62374.1 - 6.2e-06 26.4 0.0 2.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Endonuclease_7 PF02945.15 KFM62374.1 - 0.00048 20.0 0.6 0.0015 18.4 0.6 1.8 1 0 0 1 1 1 1 Recombination endonuclease VII KLRAQ PF10205.9 KFM62374.1 - 0.024 14.9 0.8 5.7 7.2 0.2 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein ARL2_Bind_BART PF11527.8 KFM62374.1 - 2.1 8.5 5.9 0.92 9.6 1.3 2.7 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Transposase_1 PF01359.18 KFM62375.1 - 6.2e-18 64.4 0.0 1.2e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM62375.1 - 5e-08 32.8 0.0 8.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62375.1 - 0.0027 17.9 0.1 0.0059 16.8 0.1 1.6 1 0 0 1 1 1 1 Transposase HTH_24 PF13412.6 KFM62375.1 - 0.0038 16.7 0.3 0.01 15.4 0.2 1.8 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 KFM62375.1 - 0.046 14.3 0.2 0.55 10.9 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain HTH_10 PF04967.12 KFM62375.1 - 0.11 12.3 0.1 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain HTH_9 PF08221.11 KFM62375.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Sushi PF00084.20 KFM62376.1 - 0.0014 19.1 1.9 0.0014 19.1 1.9 1.9 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) PRKCSH_1 PF13015.6 KFM62376.1 - 0.072 12.8 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM62377.1 - 8e-16 58.0 6.5 1.4e-15 57.3 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62377.1 - 1e-15 57.7 0.1 5.6e-15 55.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM62377.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM62377.1 - 0.0022 17.7 0.1 0.088 12.6 0.0 3.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62377.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM62377.1 - 0.021 14.9 2.1 0.031 14.3 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM62377.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KFM62378.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62378.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62378.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62378.1 - 0.0024 17.6 0.6 0.0069 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62378.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62379.1 - 3.9e-16 59.1 3.5 5.6e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62379.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62379.1 - 2e-07 30.7 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62379.1 - 0.0025 17.5 0.6 0.0075 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62379.1 - 0.027 14.6 0.4 0.089 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM62379.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62380.1 - 1.4e-14 54.1 6.2 3.1e-14 53.0 6.2 1.5 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 KFM62380.1 - 4.3e-06 26.4 2.3 6e-06 25.9 0.1 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62380.1 - 2.6e-05 23.9 2.4 0.00035 20.3 0.1 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62380.1 - 0.00018 22.1 1.2 0.00018 22.1 1.2 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 KFM62380.1 - 0.011 15.4 0.6 0.021 14.5 0.6 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Bac_DnaA_C PF08299.11 KFM62380.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix HTH_12 PF08461.10 KFM62380.1 - 0.011 15.6 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_28 PF13518.6 KFM62380.1 - 0.02 15.0 2.5 0.13 12.4 0.1 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KFM62380.1 - 0.079 12.6 0.2 0.8 9.4 0.0 2.4 2 1 1 3 3 3 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 KFM62380.1 - 0.08 12.4 3.0 4.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 KFM62380.1 - 0.13 11.8 0.3 0.5 10.0 0.0 2.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KFM62380.1 - 0.23 11.3 2.0 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.16 KFM62380.1 - 0.39 10.3 0.1 0.39 10.3 0.1 2.2 3 0 0 3 3 3 0 Sigma-70, region 4 SelP_N PF04592.14 KFM62381.1 - 6.8 6.0 11.4 11 5.3 11.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region LRR_6 PF13516.6 KFM62382.1 - 1.8e-16 58.7 7.6 0.00034 20.4 0.1 7.7 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 KFM62382.1 - 1.6e-12 47.4 5.0 0.0015 18.9 0.2 4.8 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM62382.1 - 3.3e-05 23.5 5.9 0.09 12.6 0.1 4.0 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KFM62382.1 - 9.6e-05 22.4 15.8 0.42 11.3 0.0 6.7 7 1 0 7 7 7 3 Leucine Rich Repeat SAM_Ste50p PF09235.10 KFM62382.1 - 0.0018 18.4 2.8 21 5.4 0.1 4.1 3 1 1 4 4 4 3 Ste50p, sterile alpha motif HTH_Tnp_Tc3_2 PF01498.18 KFM62384.1 - 2e-19 69.6 3.8 4.5e-19 68.5 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62384.1 - 3.1e-16 59.4 0.0 1.6e-15 57.1 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM62384.1 - 2.8e-07 31.1 4.3 2.8e-07 31.0 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM62384.1 - 0.00027 20.8 0.6 0.0046 16.8 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_29 PF13551.6 KFM62384.1 - 0.00091 19.2 0.3 0.018 15.0 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 KFM62384.1 - 0.001 19.0 0.3 0.017 15.1 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM62384.1 - 0.0013 18.8 1.2 0.26 11.4 0.0 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62384.1 - 0.02 14.7 1.8 1.1 9.2 0.0 3.0 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 KFM62384.1 - 0.025 14.7 0.6 7.8 6.7 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase TrmB PF01978.19 KFM62384.1 - 0.1 12.5 0.1 12 5.9 0.0 3.0 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_17 PF12728.7 KFM62384.1 - 0.1 12.8 0.1 17 5.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain p450 PF00067.22 KFM62388.1 - 2.6e-50 171.5 0.0 3.3e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF966 PF06136.13 KFM62388.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) HTH_Tnp_Tc3_2 PF01498.18 KFM62389.1 - 4.6e-16 58.8 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62389.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62389.1 - 2e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62389.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62389.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Pkinase_Tyr PF07714.17 KFM62390.1 - 5.3e-96 320.9 0.0 7.8e-96 320.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM62390.1 - 3.1e-46 157.9 0.0 5.5e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ephrin_lbd PF01404.19 KFM62390.1 - 1.2e-33 116.7 0.0 3.7e-33 115.0 0.0 1.8 2 0 0 2 2 2 1 Ephrin receptor ligand binding domain fn3 PF00041.21 KFM62390.1 - 4.7e-28 97.4 1.6 2.6e-13 50.1 0.1 3.0 3 0 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.6 KFM62390.1 - 2.2e-21 76.5 0.1 4.7e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.30 KFM62390.1 - 3.4e-20 72.3 0.1 6.6e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM62390.1 - 1.5e-19 69.8 0.0 4.2e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pur_ac_phosph_N PF16656.5 KFM62390.1 - 5.9e-07 30.0 0.3 0.041 14.4 0.0 2.8 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Ephrin_rec_like PF07699.13 KFM62390.1 - 0.00012 21.8 2.8 0.00012 21.8 2.8 2.5 2 1 1 3 3 2 1 Putative ephrin-receptor like Interfer-bind PF09294.10 KFM62390.1 - 0.012 15.9 0.1 0.25 11.7 0.0 2.5 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Stevor PF17410.2 KFM62390.1 - 0.016 14.7 1.0 0.038 13.5 1.0 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame XFP_N PF09364.10 KFM62390.1 - 0.024 13.5 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain DUF2369 PF10179.9 KFM62390.1 - 0.044 14.2 1.7 0.43 11.0 1.8 2.3 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2369) Haspin_kinase PF12330.8 KFM62390.1 - 0.051 12.5 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ODV-E18 PF10717.9 KFM62390.1 - 0.058 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RIFIN PF02009.16 KFM62390.1 - 0.13 12.2 0.4 0.23 11.3 0.1 1.6 2 0 0 2 2 2 0 Rifin Rhodanese PF00581.20 KFM62391.1 - 3.6e-06 27.5 0.0 4.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain adh_short PF00106.25 KFM62392.1 - 8.5e-40 136.3 0.0 5.1e-39 133.8 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM62392.1 - 8.7e-28 97.5 0.0 4.2e-27 95.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM62392.1 - 9.1e-09 35.5 0.0 1.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM62392.1 - 2e-06 27.5 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFM62392.1 - 0.0022 18.3 0.1 0.0044 17.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 KFM62392.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KFM62392.1 - 0.02 14.9 0.1 0.063 13.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KFM62392.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 KFM62392.1 - 0.039 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Wax2_C PF12076.8 KFM62392.1 - 0.051 13.3 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain DUF1776 PF08643.10 KFM62392.1 - 0.12 11.8 0.0 9 5.6 0.0 2.2 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) IlvN PF07991.12 KFM62392.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM62393.1 - 5.3e-14 52.2 0.0 8.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Transposase THAP PF05485.12 KFM62396.1 - 1.8e-07 32.0 0.7 2.2e-07 31.7 0.7 1.2 1 0 0 1 1 1 1 THAP domain Spectrin PF00435.21 KFM62398.1 - 1.4e-296 960.9 193.3 5.2e-24 84.8 6.7 17.3 17 0 0 17 17 17 17 Spectrin repeat CH PF00307.31 KFM62398.1 - 4.8e-39 132.9 0.4 2.4e-25 88.8 0.0 4.2 3 0 0 3 3 3 2 Calponin homology (CH) domain PH_9 PF15410.6 KFM62398.1 - 1.6e-21 76.9 3.5 2.4e-21 76.3 0.4 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFM62398.1 - 8e-15 55.2 0.2 3.3e-14 53.3 0.2 2.2 1 0 0 1 1 1 1 PH domain CAMSAP_CH PF11971.8 KFM62398.1 - 2e-05 24.4 0.0 5.2e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 KFM62398.1 - 0.1 12.7 1.0 4.2 7.6 0.0 4.3 3 0 0 3 3 3 0 CH-like domain in sperm protein PWWP PF00855.17 KFM62398.1 - 0.36 11.3 3.7 0.83 10.1 0.5 3.3 2 0 0 2 2 2 0 PWWP domain Imm42 PF15593.6 KFM62398.1 - 1.8 9.0 7.5 22 5.5 1.8 3.7 2 0 0 2 2 2 0 Immunity protein 42 L27 PF02828.16 KFM62399.1 - 8.1e-23 79.9 0.5 1.4e-22 79.2 0.1 1.6 2 0 0 2 2 2 1 L27 domain PDZ PF00595.24 KFM62399.1 - 1e-20 73.9 0.4 1.5e-20 73.3 0.4 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM62399.1 - 2.4e-13 49.7 0.3 5.3e-13 48.6 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM62399.1 - 0.0016 18.8 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain EAP30 PF04157.16 KFM62399.1 - 0.074 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family L27_1 PF09058.10 KFM62399.1 - 0.63 10.1 2.4 2.2 8.4 0.4 2.5 3 1 0 3 3 3 0 L27_1 HEAT PF02985.22 KFM62400.1 - 1.4e-46 152.5 34.5 0.00097 19.2 0.0 24.4 27 0 0 27 27 25 9 HEAT repeat HEAT_2 PF13646.6 KFM62400.1 - 2.9e-39 133.3 14.3 8.1e-07 29.3 0.0 14.1 7 4 7 15 15 14 8 HEAT repeats HEAT_EZ PF13513.6 KFM62400.1 - 1.4e-36 124.5 35.4 0.00062 20.2 0.0 20.7 18 4 4 22 22 20 8 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFM62400.1 - 1.8e-17 63.7 0.0 0.93 10.1 0.0 11.4 9 3 2 11 11 10 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFM62400.1 - 8.9e-17 61.6 10.7 0.0099 15.9 0.0 10.9 9 3 1 11 11 11 4 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KFM62400.1 - 4.1e-15 56.0 2.1 0.01 15.4 0.0 8.9 8 1 1 9 9 9 3 CLASP N terminal ParcG PF10274.9 KFM62400.1 - 1.3e-08 35.2 4.8 11 6.1 0.0 9.1 7 3 0 8 8 8 0 Parkin co-regulated protein UME PF08064.13 KFM62400.1 - 1.4e-08 34.5 1.1 2.6 8.0 0.0 9.4 7 2 1 8 8 8 1 UME (NUC010) domain Dopey_N PF04118.14 KFM62400.1 - 0.00017 20.8 3.0 0.95 8.5 0.0 5.6 6 0 0 6 6 6 1 Dopey, N-terminal Tti2 PF10521.9 KFM62400.1 - 0.00049 19.7 3.4 0.18 11.3 0.0 5.2 5 0 0 5 5 5 1 Tti2 family MMS19_C PF12460.8 KFM62400.1 - 0.0014 17.8 0.0 0.0014 17.8 0.0 10.6 8 3 3 12 12 12 2 RNAPII transcription regulator C-terminal DUF937 PF06078.11 KFM62400.1 - 0.0041 17.7 3.5 3.5 8.2 0.0 5.0 4 1 1 5 5 4 1 Bacterial protein of unknown function (DUF937) DUF1400 PF07176.11 KFM62400.1 - 0.013 15.7 0.2 17 5.7 0.1 4.2 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) DUF3437 PF11919.8 KFM62400.1 - 0.049 13.5 3.0 16 5.5 0.0 5.6 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) EI24 PF07264.11 KFM62400.1 - 0.076 13.3 0.0 6.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Telomere_reg-2 PF10193.9 KFM62400.1 - 0.12 12.9 2.7 48 4.4 0.0 6.0 6 0 0 6 6 6 0 Telomere length regulation protein HEAT_PBS PF03130.16 KFM62400.1 - 1.5 9.7 15.4 2.5 9.0 0.1 8.3 8 0 0 8 8 5 0 PBS lyase HEAT-like repeat TANGO2 PF05742.12 KFM62401.1 - 6e-45 154.3 0.0 6.8e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 HTH_Tnp_Tc3_2 PF01498.18 KFM62403.1 - 2.7e-14 53.1 1.0 5.1e-14 52.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62403.1 - 6.4e-14 51.9 0.0 8.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Acyl_transf_3 PF01757.22 KFM62404.1 - 1.5e-17 63.7 38.7 1.5e-17 63.7 38.7 2.0 2 0 0 2 2 2 1 Acyltransferase family DUF5624 PF18538.1 KFM62404.1 - 0.0083 16.2 1.2 0.016 15.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5624) DUF2456 PF10445.9 KFM62405.1 - 0.11 12.5 0.0 0.42 10.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2456) DUF2053 PF09767.9 KFM62406.1 - 1.5e-67 226.7 6.1 1.5e-67 226.7 6.1 1.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2053) NNMT_PNMT_TEMT PF01234.17 KFM62408.1 - 5.6e-45 153.5 0.0 6.2e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 KFM62408.1 - 0.00039 21.0 0.0 0.036 14.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM62408.1 - 0.00093 19.9 0.0 2.5 8.9 0.0 2.5 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 KFM62408.1 - 0.0051 16.6 0.0 0.17 11.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM62408.1 - 0.0056 16.5 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM62408.1 - 0.0066 17.2 0.0 0.086 13.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Ku_PK_bind PF08785.11 KFM62408.1 - 0.19 11.9 1.8 6.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Ku C terminal domain like Pkinase_Tyr PF07714.17 KFM62409.1 - 3e-85 285.6 0.0 3.8e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM62409.1 - 2.1e-38 132.2 0.0 6.1e-38 130.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 KFM62409.1 - 0.0075 16.2 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Haspin_kinase PF12330.8 KFM62409.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Protocadherin PF08374.11 KFM62409.1 - 0.054 13.5 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 KFM62409.1 - 0.094 13.6 0.0 0.18 12.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CoA_binding PF02629.19 KFM62410.1 - 7.2e-28 97.1 0.5 2.2e-27 95.5 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFM62410.1 - 4e-23 81.9 0.0 6.8e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFM62410.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Glyco_hydro_4 PF02056.16 KFM62410.1 - 0.0056 16.3 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase SseB PF07179.12 KFM62410.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 SseB protein N-terminal domain MA3 PF02847.17 KFM62411.1 - 3.4e-48 162.3 0.2 6.5e-23 80.9 0.0 2.2 2 0 0 2 2 2 2 MA3 domain Transposase_1 PF01359.18 KFM62413.1 - 4.4e-08 32.8 0.0 9.8e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) E1_DerP2_DerF2 PF02221.15 KFM62414.1 - 7.2e-10 39.4 0.3 9.3e-10 39.1 0.3 1.1 1 0 0 1 1 1 1 ML domain DUF4371 PF14291.6 KFM62415.1 - 0.0014 18.3 0.0 0.0014 18.3 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4371) GBP_C PF02841.14 KFM62415.1 - 0.23 10.8 8.6 0.35 10.2 7.5 1.8 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain HSBP1 PF06825.12 KFM62415.1 - 2.1 8.3 4.3 25 4.8 0.5 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 HTH_Tnp_Tc3_2 PF01498.18 KFM62416.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62416.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Nop PF01798.18 KFM62417.1 - 1.1e-83 280.2 0.1 1.1e-83 280.2 0.1 2.4 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFM62417.1 - 6.9e-14 52.0 0.0 6.9e-14 52.0 0.0 4.0 5 0 0 5 5 5 1 NOP5NT (NUC127) domain Actin PF00022.19 KFM62418.1 - 1.4e-17 63.5 0.1 1.1e-09 37.4 0.0 2.0 2 0 0 2 2 2 2 Actin Actin PF00022.19 KFM62419.1 - 2.5e-22 79.1 0.0 3e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFM62419.1 - 0.028 13.2 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein ABC_membrane_2 PF06472.15 KFM62420.1 - 7.9e-56 189.4 0.1 1.1e-55 188.9 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFM62420.1 - 2.8e-16 60.3 0.0 6.6e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM62420.1 - 3.9e-05 23.2 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFM62420.1 - 0.0032 18.0 0.0 0.0058 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM62420.1 - 0.0077 16.6 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFM62420.1 - 0.025 14.3 0.0 0.096 12.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_27 PF13514.6 KFM62420.1 - 0.044 13.4 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KFM62420.1 - 0.052 13.3 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KFM62420.1 - 0.079 13.4 0.1 0.42 11.1 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Peptidase_M13_N PF05649.13 KFM62421.1 - 2e-11 44.2 0.0 2.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM62422.1 - 4.3e-16 59.6 0.8 5.2e-16 59.3 0.3 1.3 2 0 0 2 2 2 1 Peptidase family M13 Flavi_M PF01004.19 KFM62422.1 - 0.042 13.6 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Peptidase_M13_N PF05649.13 KFM62424.1 - 2.5e-21 76.8 0.2 3.6e-21 76.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM62424.1 - 2.3e-14 53.5 0.0 4.8e-13 49.2 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M48_N PF16491.5 KFM62424.1 - 0.1 12.5 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices Flavi_M PF01004.19 KFM62424.1 - 0.17 11.7 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Trypsin PF00089.26 KFM62425.1 - 4.8e-19 69.1 0.0 5.3e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_S6 PF02395.16 KFM62425.1 - 0.017 13.2 0.0 0.017 13.2 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin A1 protease Sushi PF00084.20 KFM62427.1 - 8.8e-22 77.5 5.0 3.8e-11 43.4 1.1 2.4 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Keratin_B2 PF01500.17 KFM62427.1 - 0.26 11.3 10.3 1 9.3 10.3 1.8 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein cEGF PF12662.7 KFM62427.1 - 6.7 6.7 7.4 23 5.1 0.3 3.3 2 1 0 2 2 2 0 Complement Clr-like EGF-like DDE_3 PF13358.6 KFM62429.1 - 3.1e-16 59.4 0.1 3.4e-15 56.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62429.1 - 8.2e-16 58.0 6.5 1.5e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM62429.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM62429.1 - 0.0027 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62429.1 - 0.017 15.2 0.1 0.068 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM62429.1 - 0.037 14.1 0.4 0.037 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM62430.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62430.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62430.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62430.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62430.1 - 0.027 14.6 0.4 0.086 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM62430.1 - 2.1 9.0 15.6 0.12 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-C2H2_11 PF16622.5 KFM62431.1 - 1.5 8.7 6.1 0.42 10.4 2.7 1.8 2 0 0 2 2 2 0 zinc-finger C2H2-type Atthog PF18800.1 KFM62432.1 - 2.2e-76 254.5 7.3 2.9e-76 254.1 7.3 1.2 1 0 0 1 1 1 1 Attenuator of Hedgehog L_HMGIC_fpl PF10242.9 KFM62432.1 - 0.00082 19.6 9.3 0.0019 18.5 9.3 1.6 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF2975 PF11188.8 KFM62432.1 - 7.5 6.4 12.2 8.2 6.3 7.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) HTH_Tnp_Tc3_2 PF01498.18 KFM62433.1 - 9e-17 61.1 2.4 6.7e-16 58.3 2.2 2.4 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62433.1 - 1.6e-13 50.6 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62433.1 - 3.3e-07 30.0 1.6 8e-07 28.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62433.1 - 0.0031 17.3 0.5 0.0087 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62433.1 - 3.3 8.4 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62434.1 - 4.6e-16 58.8 1.4 1e-15 57.7 1.4 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62434.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM62434.1 - 2.2e-06 28.2 9.2 2.8e-06 27.9 2.1 2.7 3 0 0 3 3 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62434.1 - 0.0013 18.8 2.2 0.042 14.0 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KFM62434.1 - 0.0021 17.9 0.4 0.22 11.5 0.0 2.5 2 0 0 2 2 2 1 MarR family PAX PF00292.18 KFM62434.1 - 0.005 16.8 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_Crp_2 PF13545.6 KFM62434.1 - 0.019 14.9 1.2 0.067 13.2 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_3 PF01381.22 KFM62434.1 - 0.025 14.7 0.5 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix HTH_33 PF13592.6 KFM62434.1 - 0.04 13.6 0.2 0.11 12.2 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_29 PF13551.6 KFM62434.1 - 0.099 12.7 1.3 5.8 7.0 0.2 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_24 PF13412.6 KFM62434.1 - 0.18 11.4 1.6 2 8.1 0.0 2.6 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM62434.1 - 0.33 10.8 4.1 5.6 6.9 0.1 3.3 3 0 0 3 3 3 0 Homeodomain-like domain zf-C3HC4_2 PF13923.6 KFM62436.1 - 4.7e-07 29.5 7.9 7.5e-07 28.9 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM62436.1 - 2.8e-05 23.9 7.4 4.4e-05 23.2 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFM62436.1 - 0.00034 20.7 8.3 0.00058 20.0 8.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFM62436.1 - 0.00095 19.4 8.2 0.0015 18.8 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM62436.1 - 0.0012 18.8 7.0 0.0019 18.1 7.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFM62436.1 - 0.0034 17.2 6.7 0.0057 16.5 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM62436.1 - 0.093 12.8 7.3 0.52 10.4 6.3 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.6 KFM62436.1 - 0.26 11.2 3.4 0.41 10.5 3.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein MA3 PF02847.17 KFM62437.1 - 4.2e-27 94.4 1.9 4.2e-27 94.4 1.9 2.0 2 0 0 2 2 2 1 MA3 domain Cnd1 PF12717.7 KFM62437.1 - 0.0038 17.3 0.1 0.0099 15.9 0.1 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Apt1 PF10351.9 KFM62438.1 - 0.046 12.6 5.7 0.039 12.8 5.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain MID_MedPIWI PF18296.1 KFM62438.1 - 0.12 12.1 5.7 0.13 12.0 5.7 1.1 1 0 0 1 1 1 0 MID domain of medPIWI SSP160 PF06933.11 KFM62438.1 - 0.15 10.2 9.7 0.15 10.3 9.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CCDC106 PF15794.5 KFM62438.1 - 0.22 11.2 11.8 0.26 11.0 11.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SR-25 PF10500.9 KFM62438.1 - 0.4 10.3 32.3 0.5 9.9 32.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 KFM62438.1 - 0.62 8.1 27.0 0.7 7.9 27.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Presenilin PF01080.17 KFM62438.1 - 0.67 8.6 1.8 0.64 8.7 1.8 1.0 1 0 0 1 1 1 0 Presenilin Pap_E4 PF02711.14 KFM62438.1 - 2.7 9.0 10.6 6 7.9 10.6 1.6 1 1 0 1 1 1 0 E4 protein DAP PF15228.6 KFM62439.1 - 2.1e-31 109.0 2.4 2.3e-31 108.9 2.4 1.0 1 0 0 1 1 1 1 Death-associated protein RsfS PF02410.15 KFM62440.1 - 1.8e-22 79.6 0.1 4.2e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation FPP PF05911.11 KFM62440.1 - 0.0021 16.4 3.0 0.0023 16.2 3.0 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil E1_UFD PF09358.10 KFM62440.1 - 0.043 14.5 0.8 0.22 12.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin fold domain polyprenyl_synt PF00348.17 KFM62441.1 - 8.8e-18 64.3 0.0 1.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase NLRC4_HD2 PF17776.1 KFM62442.1 - 0.0015 19.1 0.4 0.0025 18.3 0.2 1.5 1 1 0 1 1 1 1 NLRC4 helical domain HD2 DUF4618 PF15397.6 KFM62442.1 - 0.0043 16.5 0.3 0.0057 16.1 0.3 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) DASH_Duo1 PF08651.10 KFM62442.1 - 0.24 11.2 5.0 0.12 12.1 0.5 2.5 2 1 1 3 3 3 0 DASH complex subunit Duo1 p450 PF00067.22 KFM62443.1 - 3.7e-93 312.8 1.0 5e-93 312.4 1.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Serum_albumin PF00273.20 KFM62443.1 - 0.3 10.9 3.5 0.16 11.7 0.4 2.1 2 0 0 2 2 2 0 Serum albumin family DUF1397 PF07165.11 KFM62444.1 - 9.2e-06 25.2 12.0 9.2e-06 25.2 12.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1397) DUF19 PF01579.18 KFM62444.1 - 0.068 13.0 21.5 0.18 11.6 21.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF19) HTH_Tnp_Tc3_2 PF01498.18 KFM62445.1 - 2e-16 60.0 2.2 4.5e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62445.1 - 9.7e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62446.1 - 1.7e-09 37.8 0.3 3.3e-09 36.9 0.3 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM62446.1 - 0.008 16.0 0.1 0.098 12.5 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62446.1 - 0.05 13.7 0.3 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KFM62446.1 - 0.081 13.2 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 Transposase DUF5429 PF17494.2 KFM62446.1 - 1.6 8.8 7.6 2.7 8.1 0.3 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5429) p450 PF00067.22 KFM62447.1 - 4e-41 141.2 1.2 4.4e-41 141.1 1.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 KIF1B PF12423.8 KFM62449.1 - 0.069 13.6 0.2 0.13 12.7 0.2 1.6 1 1 0 1 1 1 0 Kinesin protein 1B OSCP PF00213.18 KFM62449.1 - 0.086 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF4806 PF16064.5 KFM62449.1 - 0.09 13.1 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) MPS-4 PF17523.2 KFM62450.1 - 0.12 12.5 1.3 0.13 12.4 1.3 1.1 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Drf_FH1 PF06346.12 KFM62452.1 - 1.8 8.3 32.6 3.5 7.3 32.6 1.4 1 0 0 1 1 1 0 Formin Homology Region 1 DSS1_SEM1 PF05160.13 KFM62453.1 - 6.8 6.8 16.2 8.6 6.5 0.0 4.5 3 1 1 4 4 4 0 DSS1/SEM1 family ATP_bind_1 PF03029.17 KFM62454.1 - 7e-81 271.5 0.1 1.1e-80 270.9 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KFM62454.1 - 2.3e-06 27.3 0.9 1.3e-05 24.8 0.1 2.4 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM62454.1 - 3.4e-05 23.9 0.0 0.00025 21.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KFM62454.1 - 6.9e-05 22.7 0.1 0.00022 21.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KFM62454.1 - 7e-05 22.8 0.0 0.12 12.3 0.1 2.3 2 0 0 2 2 2 2 NTPase FeoB_N PF02421.18 KFM62454.1 - 0.00013 21.5 0.1 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF87 PF01935.17 KFM62454.1 - 0.00016 21.8 0.1 0.059 13.5 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain G-alpha PF00503.20 KFM62454.1 - 0.00022 20.5 1.3 0.0047 16.1 0.0 2.6 2 1 1 3 3 3 1 G-protein alpha subunit cobW PF02492.19 KFM62454.1 - 0.00033 20.3 0.2 0.37 10.4 0.0 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KFM62454.1 - 0.00057 19.6 0.0 0.096 12.3 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 KFM62454.1 - 0.00074 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain TsaE PF02367.17 KFM62454.1 - 0.00075 19.5 0.2 0.0042 17.1 0.0 2.2 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KFM62454.1 - 0.0014 17.9 0.1 0.0032 16.7 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 KFM62454.1 - 0.0023 17.9 0.1 3.6 7.5 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase Arf PF00025.21 KFM62454.1 - 0.0031 17.0 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_15 PF13175.6 KFM62454.1 - 0.0053 16.5 0.2 0.027 14.2 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 KFM62454.1 - 0.0065 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM62454.1 - 0.0084 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 KFM62454.1 - 0.0086 15.8 0.0 0.053 13.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 KFM62454.1 - 0.0091 16.5 0.1 0.94 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 KFM62454.1 - 0.011 15.7 0.0 1.6 8.6 0.0 2.5 1 1 0 2 2 2 0 AAA domain Ras PF00071.22 KFM62454.1 - 0.013 15.1 0.0 2.1 7.9 0.0 2.5 2 1 0 2 2 2 0 Ras family Roc PF08477.13 KFM62454.1 - 0.016 15.4 0.0 0.79 10.0 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KFM62454.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KFM62454.1 - 0.017 14.3 0.0 0.028 13.7 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.18 KFM62454.1 - 0.023 14.5 0.1 0.059 13.1 0.1 1.9 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KFM62454.1 - 0.029 14.9 0.1 0.48 11.0 0.0 2.7 2 1 1 3 3 3 0 AAA domain ATPase_2 PF01637.18 KFM62454.1 - 0.045 13.7 0.3 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFM62454.1 - 0.056 13.8 0.0 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KFM62454.1 - 0.064 13.0 0.0 0.72 9.6 0.0 2.4 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 KFM62454.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KFM62454.1 - 0.07 12.1 0.0 0.4 9.6 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KFM62454.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Microtub_bd PF16796.5 KFM62454.1 - 0.095 12.6 0.2 0.23 11.4 0.0 1.7 2 0 0 2 2 1 0 Microtubule binding Zeta_toxin PF06414.12 KFM62454.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KFM62454.1 - 0.11 11.8 0.3 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family SMC_N PF02463.19 KFM62454.1 - 0.12 11.8 0.4 4.8 6.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 KFM62454.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 KFM62454.1 - 0.14 11.5 2.2 3.7 7.0 0.0 2.5 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit DHHC PF01529.20 KFM62455.1 - 1.5e-36 125.5 15.7 1.5e-36 125.5 15.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase p450 PF00067.22 KFM62457.1 - 0.00015 20.6 0.2 0.00016 20.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fib_succ_major PF09603.10 KFM62459.1 - 0.098 13.3 0.0 0.098 13.3 0.0 1.1 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) NPCBM_assoc PF10633.9 KFM62459.1 - 0.15 12.3 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase PUB PF09409.10 KFM62461.1 - 8.4e-14 51.3 0.1 1.8e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 PUB domain MAP7 PF05672.11 KFM62461.1 - 0.0085 15.8 8.9 0.013 15.2 8.9 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Ferrochelatase PF00762.19 KFM62461.1 - 0.021 13.9 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 Ferrochelatase FERM_F2 PF18377.1 KFM62461.1 - 0.07 13.1 1.2 0.11 12.4 0.4 1.7 2 0 0 2 2 2 0 FERM F2 acyl-CoA binding protein-like domain DUF4835 PF16119.5 KFM62462.1 - 0.063 12.4 0.1 0.084 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) Peptidase_C69 PF03577.15 KFM62463.1 - 7.5e-08 31.7 0.1 1e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 KFM62463.1 - 0.00083 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase SRTM1 PF15872.5 KFM62465.1 - 0.03 14.5 0.1 0.049 13.8 0.1 1.3 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 DUF4342 PF14242.6 KFM62465.1 - 0.63 10.1 2.2 1.1 9.4 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Ig_3 PF13927.6 KFM62466.1 - 1.2e-15 57.9 1.6 4e-13 49.8 0.3 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM62466.1 - 9.9e-15 54.4 0.5 7.6e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM62466.1 - 1.8e-13 50.5 1.5 1.7e-10 40.9 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM62466.1 - 3.3e-13 49.8 0.5 1.3e-10 41.5 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM62466.1 - 9.4e-09 35.4 1.1 0.00082 19.5 0.2 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM62466.1 - 0.00016 22.0 0.0 0.066 13.6 0.0 2.6 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM62466.1 - 0.00033 20.9 0.0 0.83 10.0 0.0 2.5 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFM62466.1 - 0.00079 19.0 0.0 0.98 9.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C2-set PF05790.15 KFM62466.1 - 0.0027 17.9 0.8 0.11 12.7 0.0 2.8 2 1 1 3 3 3 1 Immunoglobulin C2-set domain C2-set_2 PF08205.12 KFM62466.1 - 0.0029 17.6 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain L27_1 PF09058.10 KFM62467.1 - 1.9e-30 104.6 2.2 2.5e-30 104.2 2.2 1.2 1 0 0 1 1 1 1 L27_1 Beta-Casp PF10996.8 KFM62469.1 - 4.9e-26 91.2 0.1 3.4e-25 88.5 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KFM62469.1 - 2.5e-21 76.0 0.0 4.8e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KFM62469.1 - 5.2e-18 64.7 0.1 9.3e-18 63.9 0.1 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KFM62469.1 - 1.8e-09 37.4 1.0 1.6e-08 34.3 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFM62469.1 - 2.1e-09 37.7 0.2 9.8e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KFM62469.1 - 2.4e-05 24.3 0.0 0.0001 22.3 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFM62469.1 - 0.0025 17.1 0.0 0.0094 15.2 0.0 2.0 1 1 0 1 1 1 1 Putative beta-lactamase-like family CPSF73-100_C PF11718.8 KFM62469.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DDE_3 PF13358.6 KFM62471.1 - 9.9e-22 77.3 0.0 5.5e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62471.1 - 1.1e-15 57.6 2.2 1.1e-15 57.6 2.2 2.0 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM62471.1 - 6.6e-07 29.0 1.6 1.2e-06 28.1 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62471.1 - 0.0037 17.0 1.4 0.014 15.2 0.5 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62471.1 - 0.024 14.8 1.9 0.17 12.0 0.5 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.6 KFM62473.1 - 2.9e-06 27.1 0.0 3.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62474.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62474.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62475.1 - 4.6e-16 58.8 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62475.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62475.1 - 2e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62475.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62475.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Shisa PF13908.6 KFM62476.1 - 1.9e-11 44.6 9.9 1.9e-11 44.6 9.9 2.8 1 1 2 3 3 3 2 Wnt and FGF inhibitory regulator MtrF PF09472.10 KFM62476.1 - 0.026 13.9 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) CCDC66 PF15236.6 KFM62477.1 - 5.6e-26 91.2 33.0 5.6e-26 91.2 33.0 2.4 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 66 Strabismus PF06638.11 KFM62477.1 - 1.1 7.8 11.1 2 7.0 11.1 1.4 1 0 0 1 1 1 0 Strabismus protein Nucleopor_Nup85 PF07575.13 KFM62479.1 - 7.8e-75 252.5 6.5 8.8e-75 252.4 6.5 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Trans_coact PF16805.5 KFM62480.1 - 0.011 15.8 0.6 0.038 14.1 0.2 2.1 2 0 0 2 2 2 0 Phage late-transcription coactivator PPR_2 PF13041.6 KFM62481.1 - 7.3e-31 106.1 4.5 1.2e-09 38.2 0.1 4.4 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.6 KFM62481.1 - 3.7e-20 71.7 0.3 7e-11 42.0 0.2 4.3 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 KFM62481.1 - 2.8e-16 58.5 10.1 1.1e-05 25.4 0.0 5.5 4 1 0 4 4 4 3 PPR repeat PPR_1 PF12854.7 KFM62481.1 - 1.2e-13 50.5 7.2 3.2e-06 26.7 0.0 6.1 6 0 0 6 6 6 4 PPR repeat PPR_long PF17177.4 KFM62481.1 - 1.5e-09 37.6 0.0 4.4e-05 23.0 0.0 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP Helicase_C PF00271.31 KFM62482.1 - 3.4e-17 62.8 0.1 1.4e-16 60.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 KFM62482.1 - 4.5e-13 49.4 0.0 1.2e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFM62482.1 - 2.4e-06 27.8 0.0 4.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFM62482.1 - 0.0087 15.8 0.2 0.017 14.9 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM62482.1 - 0.12 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ApbA PF02558.16 KFM62482.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Dicer_dimer PF03368.14 KFM62483.1 - 1.3e-05 25.3 0.2 0.027 14.6 0.0 2.9 2 1 0 2 2 2 2 Dicer dimerisation domain dsrm PF00035.26 KFM62483.1 - 0.00053 20.6 0.1 1.5 9.5 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif T2SSE PF00437.20 KFM62483.1 - 0.0041 16.2 0.0 0.0061 15.6 0.0 1.4 1 1 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 KFM62483.1 - 0.013 16.0 0.2 0.14 12.6 0.0 2.5 1 1 2 3 3 3 0 ABC transporter ATPase PF06745.13 KFM62483.1 - 0.016 14.5 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 KFM62483.1 - 0.022 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 KFM62483.1 - 0.025 14.6 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KFM62483.1 - 0.042 13.7 0.0 0.095 12.6 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase ANT PF03374.14 KFM62483.1 - 0.087 13.1 0.1 3.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain AAA_25 PF13481.6 KFM62483.1 - 0.097 12.2 0.0 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KFM62483.1 - 0.12 12.1 0.2 0.43 10.3 0.1 2.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase AMP-binding PF00501.28 KFM62484.1 - 1.3e-111 373.2 0.0 1.8e-111 372.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM62484.1 - 4.6e-05 24.3 0.0 0.00013 22.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIN_6 PF17146.4 KFM62484.1 - 0.091 13.3 0.1 0.26 11.8 0.1 1.8 1 1 0 1 1 1 0 PIN domain of ribonuclease AMP-binding_C PF13193.6 KFM62485.1 - 5.7e-07 30.4 0.0 7.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PH_17 PF18012.1 KFM62487.1 - 4.9e-27 93.4 0.8 9.8e-27 92.5 0.8 1.5 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 KFM62487.1 - 9.2e-19 67.6 1.2 1.5e-18 66.9 1.2 1.3 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 KFM62487.1 - 1e-09 38.8 0.0 3e-05 24.5 0.0 3.1 3 0 0 3 3 3 2 PH domain PDZ_6 PF17820.1 KFM62487.1 - 5.9e-06 26.0 0.1 2e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM62487.1 - 0.00043 20.6 0.1 0.0011 19.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain RRM_1 PF00076.22 KFM62488.1 - 2.7e-41 139.3 0.2 2.2e-24 85.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KFM62488.1 - 1.6e-24 86.8 0.1 1.6e-24 86.8 0.1 2.4 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KFM62488.1 - 3.5e-06 26.8 0.0 0.0045 16.8 0.0 3.3 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KFM62488.1 - 6.6e-05 22.5 0.0 0.04 13.5 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KFM62488.1 - 0.0016 18.3 0.0 4.7 7.1 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF1866) RRM_7 PF16367.5 KFM62488.1 - 0.015 15.4 0.0 0.1 12.7 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM62488.1 - 0.095 12.7 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Macoilin PF09726.9 KFM62488.1 - 6.7 5.1 21.3 9.3 4.7 21.3 1.1 1 0 0 1 1 1 0 Macoilin family Acyl-CoA_dh_1 PF00441.24 KFM62489.1 - 4.8e-08 33.4 0.1 5e-08 33.3 0.1 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TPR_1 PF00515.28 KFM62490.1 - 1.1e-10 40.8 0.0 2.4e-05 24.0 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM62490.1 - 3.3e-10 39.3 0.0 0.00019 21.4 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM62490.1 - 3.8e-10 39.1 0.0 4.9e-05 23.1 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM62490.1 - 3.8e-09 36.1 0.0 6.3e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 TPR repeat TPR_7 PF13176.6 KFM62490.1 - 1.4e-06 27.9 0.0 0.051 13.6 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM62490.1 - 2.2e-06 28.1 0.0 2.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM62490.1 - 3.6e-06 27.2 0.1 0.085 13.2 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM62490.1 - 6.3e-06 26.6 0.0 0.0017 19.0 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM62490.1 - 7.1e-06 25.7 0.2 0.014 15.2 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM62490.1 - 1.1e-05 25.5 0.0 0.0008 19.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM62490.1 - 3.8e-05 24.3 0.0 3.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.8 KFM62490.1 - 0.0027 16.7 0.1 0.0028 16.6 0.1 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 KFM62490.1 - 0.0038 17.3 0.0 0.0048 17.0 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF4698 PF15769.5 KFM62490.1 - 0.051 12.6 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) TPR_6 PF13174.6 KFM62490.1 - 0.067 13.9 0.0 3.4 8.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM62490.1 - 0.093 13.0 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PCI PF01399.27 KFM62491.1 - 1.3e-21 77.1 0.2 4.4e-21 75.4 0.1 2.0 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 KFM62491.1 - 7.9e-19 67.8 0.0 7.9e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 KFM62491.1 - 0.0069 16.4 6.2 0.078 13.1 1.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Phage_term_smal PF05944.12 KFM62491.1 - 0.085 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Phage small terminase subunit CDC37_C PF08564.10 KFM62491.1 - 0.31 11.2 1.5 4.3 7.5 0.0 2.7 3 0 0 3 3 3 0 Cdc37 C terminal domain Golgin_A5 PF09787.9 KFM62492.1 - 4.4e-105 351.5 31.4 4.4e-105 351.5 31.4 3.3 1 1 2 3 3 3 2 Golgin subfamily A member 5 KELK PF15796.5 KFM62492.1 - 0.00015 22.1 10.1 0.00015 22.1 10.1 7.1 4 2 4 8 8 8 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Myb_DNA-binding PF00249.31 KFM62493.1 - 1.4e-45 153.2 18.6 2.6e-17 62.7 2.3 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM62493.1 - 1.7e-35 121.1 19.6 4e-18 65.4 2.4 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFM62493.1 - 0.0018 18.1 11.8 0.027 14.3 0.3 4.2 2 1 2 4 4 4 2 Myb DNA-binding like SLIDE PF09111.10 KFM62493.1 - 0.006 16.6 0.5 2.6 8.1 0.0 3.1 1 1 2 3 3 3 2 SLIDE Rap1_C PF11626.8 KFM62493.1 - 0.028 14.5 4.8 2.4 8.3 0.2 3.1 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HEPN_Swt1 PF18731.1 KFM62493.1 - 0.1 12.9 0.7 0.37 11.2 0.7 2.0 1 0 0 1 1 1 0 Swt1-like HEPN SANT_DAMP1_like PF16282.5 KFM62493.1 - 1.3 9.3 4.8 1.3 9.3 0.0 3.0 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 SlyX PF04102.12 KFM62494.1 - 0.038 14.6 0.6 0.039 14.6 0.6 1.1 1 0 0 1 1 1 0 SlyX Syntaxin-18_N PF10496.9 KFM62495.1 - 1.2e-21 76.8 2.1 1.4e-21 76.5 0.2 2.1 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SIKE PF05769.11 KFM62495.1 - 0.034 14.1 0.9 0.067 13.1 0.8 1.4 1 1 0 1 1 1 0 SIKE family Pkinase PF00069.25 KFM62496.1 - 4.4e-33 114.8 0.0 5e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM62496.1 - 1.8e-27 96.3 0.0 2e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM62496.1 - 0.013 14.2 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFM62496.1 - 0.03 14.2 0.0 0.28 11.1 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KFM62497.1 - 1.1e-17 64.3 0.0 1.8e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM62497.1 - 2.5e-12 46.7 0.0 4.6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PI3K_1B_p101 PF10486.9 KFM62497.1 - 0.026 12.3 7.2 0.031 12.1 7.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-C2HE PF16278.5 KFM62497.1 - 0.19 12.2 0.3 0.19 12.2 0.3 2.2 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Lipocalin PF00061.23 KFM62498.1 - 5.2e-15 55.9 0.8 5.6e-15 55.8 0.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFM62498.1 - 1.5e-06 28.1 0.7 1.7e-06 28.0 0.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family IF-2B PF01008.17 KFM62499.1 - 3.6e-69 233.1 0.0 4e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Importin_rep_3 PF18806.1 KFM62499.1 - 0.00068 19.6 0.1 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 Importin 13 repeat PS_pyruv_trans PF04230.13 KFM62499.1 - 0.02 14.8 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Glyco_transf_49 PF13896.6 KFM62500.1 - 3.2e-51 174.6 0.0 3.7e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 KFM62500.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 ESR1_C PF12743.7 KFM62500.1 - 0.28 11.0 1.1 2.7 7.9 0.1 2.4 1 1 1 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal WBP-1 PF11669.8 KFM62501.1 - 0.47 11.1 4.5 4.7 7.9 0.2 2.5 1 1 1 2 2 2 0 WW domain-binding protein 1 PLAT PF01477.23 KFM62502.1 - 5.2e-20 72.2 0.2 1.4e-19 70.8 0.1 1.7 2 0 0 2 2 2 1 PLAT/LH2 domain REJ PF02010.15 KFM62503.1 - 1.8e-33 116.0 0.0 5.4e-33 114.5 0.0 1.8 2 0 0 2 2 2 1 REJ domain REJ PF02010.15 KFM62504.1 - 4.8e-13 48.7 0.0 5.5e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 REJ domain Ino80_Iec3 PF14612.6 KFM62504.1 - 0.18 12.5 0.0 0.26 11.9 0.0 1.2 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling PKD PF00801.20 KFM62505.1 - 2.8e-36 123.2 14.9 9.4e-10 38.2 0.1 6.5 6 1 0 6 6 6 6 PKD domain Y_Y_Y PF07495.13 KFM62505.1 - 0.0039 17.1 0.9 1.2 9.2 0.0 3.4 4 0 0 4 4 4 2 Y_Y_Y domain He_PIG PF05345.12 KFM62505.1 - 0.05 13.8 0.5 97 3.3 0.0 4.7 4 2 0 4 4 4 0 Putative Ig domain Deltameth_res PF16020.5 KFM62506.1 - 0.084 12.8 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Deltamethrin resistance zf-C2H2 PF00096.26 KFM62507.1 - 6.2e-14 51.6 15.7 1e-05 25.7 1.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62507.1 - 1.9e-09 37.6 13.4 0.00045 20.8 1.7 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM62507.1 - 1.9e-05 24.5 9.6 0.044 13.8 0.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger C1_4 PF07975.12 KFM62507.1 - 0.00031 20.9 2.4 0.00031 20.9 2.4 1.9 1 1 1 2 2 2 2 TFIIH C1-like domain LIM PF00412.22 KFM62507.1 - 0.0014 18.8 3.9 0.0025 18.0 2.6 2.0 1 1 1 2 2 2 1 LIM domain zf-H2C2_2 PF13465.6 KFM62507.1 - 0.0016 18.8 14.3 0.0056 17.0 0.9 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 KFM62507.1 - 0.012 15.8 6.9 0.019 15.3 1.3 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding EGF_CA PF07645.15 KFM62507.1 - 0.015 15.4 3.3 1.8 8.8 0.3 2.6 2 1 1 3 3 3 0 Calcium-binding EGF domain zf-C2H2_3 PF13878.6 KFM62507.1 - 0.044 13.6 6.2 2.6 8.0 0.2 3.3 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-LYAR PF08790.11 KFM62507.1 - 0.051 13.5 10.0 0.26 11.2 1.1 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Actin_micro PF17003.5 KFM62507.1 - 0.052 12.7 5.6 0.067 12.4 0.8 2.0 1 1 1 2 2 2 0 Putative actin-like family zf-C2H2_3rep PF18868.1 KFM62507.1 - 0.053 14.2 4.3 0.51 11.0 0.8 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 KFM62507.1 - 0.093 12.8 2.4 0.17 11.9 0.2 2.0 1 1 1 2 2 2 0 CpXC protein zf_C2H2_ZHX PF18387.1 KFM62507.1 - 0.1 12.3 4.9 1 9.1 0.4 2.6 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KFM62507.1 - 0.1 12.9 12.4 0.45 10.9 1.3 3.4 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFM62507.1 - 0.1 12.2 4.1 0.57 9.8 0.3 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 KFM62507.1 - 0.11 12.6 3.9 0.2 11.7 3.9 1.6 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 KFM62507.1 - 0.2 11.6 4.0 1.7 8.6 4.0 2.3 1 1 0 1 1 1 0 zinc-ribbon domain FOXP-CC PF16159.5 KFM62507.1 - 0.25 12.0 4.6 1.9 9.2 0.4 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-met PF12874.7 KFM62507.1 - 0.27 11.7 14.7 4.5 7.8 0.6 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF629 PF04780.12 KFM62507.1 - 0.3 9.6 6.6 0.63 8.5 6.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF629) RIG-I_C-RD PF11648.8 KFM62507.1 - 1.1 9.5 8.4 1.9 8.7 0.9 2.7 2 1 1 3 3 3 0 C-terminal domain of RIG-I zf-C2HE PF16278.5 KFM62507.1 - 1.5 9.3 7.9 8.1 7.0 1.5 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KFM62507.1 - 2.2 8.1 14.4 1.2 9.0 0.5 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFM62507.1 - 2.3 8.4 6.3 2.8 8.1 3.8 2.4 2 1 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.21 KFM62507.1 - 3 8.1 11.4 4.4 7.5 7.8 2.1 1 1 1 2 2 2 0 FYVE zinc finger zf-H2C2_5 PF13909.6 KFM62507.1 - 6.8 6.6 10.4 6.9 6.5 1.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf_ZIC PF18366.1 KFM62507.1 - 8.4 6.6 10.8 0.15 12.2 1.3 2.5 3 0 0 3 3 2 0 Zic proteins zinc finger domain Syntaxin PF00804.25 KFM62510.1 - 3e-55 187.0 17.0 4.4e-55 186.5 17.0 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFM62510.1 - 5.6e-15 55.1 2.5 5.6e-15 55.1 2.5 2.5 3 0 0 3 3 2 1 SNARE domain Syntaxin_2 PF14523.6 KFM62510.1 - 2.3e-07 31.1 7.6 2.3e-07 31.1 7.6 2.6 2 1 0 2 2 2 1 Syntaxin-like protein Baculo_PEP_C PF04513.12 KFM62510.1 - 0.0023 18.0 10.2 0.18 11.9 1.0 3.3 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 KFM62510.1 - 0.0088 14.1 17.6 0.072 11.0 17.4 2.0 1 1 0 1 1 1 1 Prominin EIID-AGA PF03613.14 KFM62510.1 - 0.0098 15.1 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component MtrB PF05440.12 KFM62510.1 - 0.063 13.7 0.2 0.063 13.7 0.2 2.7 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B ETRAMP PF09716.10 KFM62510.1 - 0.079 13.0 8.2 0.071 13.2 4.1 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CHASE3 PF05227.13 KFM62510.1 - 0.1 12.5 7.2 0.095 12.6 3.9 2.5 2 1 0 2 2 2 0 CHASE3 domain COG5 PF10392.9 KFM62510.1 - 0.11 12.6 11.2 0.22 11.7 5.1 3.0 2 2 1 3 3 3 0 Golgi transport complex subunit 5 DUF2116 PF09889.9 KFM62510.1 - 0.14 12.1 3.1 0.35 10.9 3.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Mod_r PF07200.13 KFM62510.1 - 0.15 12.2 16.1 0.14 12.2 2.6 3.2 1 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Leucyl-specific PF14795.6 KFM62510.1 - 0.17 11.9 0.3 0.62 10.2 0.3 2.0 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain DUF2207 PF09972.9 KFM62510.1 - 0.35 9.6 5.6 0.25 10.1 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DRE2_N PF16803.5 KFM62510.1 - 0.39 11.0 4.7 4 7.7 1.1 2.4 1 1 1 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus HAUS6_N PF14661.6 KFM62510.1 - 0.58 9.7 9.6 1.2 8.6 9.5 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ABC_tran_CTD PF16326.5 KFM62510.1 - 0.71 10.2 12.2 0.87 9.9 1.2 3.4 3 1 1 4 4 4 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 KFM62510.1 - 0.87 10.1 10.8 1.8 9.1 0.3 3.9 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein LOH1CR12 PF10158.9 KFM62510.1 - 1.2 9.2 9.7 0.37 10.8 3.7 2.5 2 1 0 2 2 2 0 Tumour suppressor protein Lzipper-MIP1 PF14389.6 KFM62510.1 - 1.3 9.3 9.7 0.088 13.1 0.8 2.7 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 T2SSF PF00482.23 KFM62510.1 - 2.4 8.1 10.1 3.7 7.5 2.4 3.7 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein F FlaC_arch PF05377.11 KFM62510.1 - 4.8 7.7 11.7 9.1 6.8 0.1 4.0 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 KFM62510.1 - 5 7.2 16.7 1.8 8.7 4.1 3.6 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Lge1 PF11488.8 KFM62510.1 - 6.7 7.0 9.9 2.8 8.2 0.3 3.4 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 Myco_arth_vir_N PF09610.10 KFM62510.1 - 8.4 6.6 10.8 17 5.6 0.2 2.4 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Plexin_cytopl PF08337.12 KFM62511.1 - 1.2e-34 120.0 0.0 1.3e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Plexin_cytopl PF08337.12 KFM62512.1 - 2.1e-137 459.2 0.0 3e-137 458.6 0.0 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.19 KFM62512.1 - 3.3e-50 171.1 0.1 6.7e-50 170.1 0.1 1.5 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 KFM62512.1 - 1.6e-38 130.7 8.9 4.6e-12 45.8 0.1 5.7 5 0 0 5 5 5 4 IPT/TIG domain TIG_2 PF18020.1 KFM62512.1 - 2.7e-23 82.4 0.6 9.8e-23 80.6 0.0 2.4 3 0 0 3 3 3 1 TIG domain found in plexin TIG_plexin PF17960.1 KFM62512.1 - 8.4e-22 77.0 5.5 6.7e-20 70.9 0.0 3.8 4 0 0 4 4 4 2 TIG domain PSI PF01437.25 KFM62512.1 - 4.4e-15 56.0 52.6 2.8e-08 34.2 14.4 3.7 3 0 0 3 3 3 3 Plexin repeat ubiquitin PF00240.23 KFM62512.1 - 0.12 12.1 0.2 5.5 6.8 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin family PSI_integrin PF17205.3 KFM62512.1 - 2.6 7.8 47.3 0.43 10.3 13.1 3.7 3 0 0 3 3 3 0 Integrin plexin domain HTH_Tnp_Tc3_2 PF01498.18 KFM62513.1 - 4.7e-16 58.8 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62513.1 - 1.3e-13 50.9 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62513.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62513.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62513.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 KFM62515.1 - 5.6e-78 254.2 100.2 4.2e-08 33.3 4.1 11.8 12 0 0 12 12 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62515.1 - 2.6e-50 166.2 109.8 6.6e-06 26.3 2.6 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62515.1 - 6.1e-35 116.9 104.7 0.00027 21.5 3.3 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM62515.1 - 7.5e-24 83.4 88.8 0.00015 22.1 1.5 11.3 11 0 0 11 11 11 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM62515.1 - 4e-20 71.3 95.2 0.0016 18.4 1.1 11.5 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM62515.1 - 7.8e-14 51.5 79.3 0.0086 16.3 1.8 11.3 9 2 2 11 11 11 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM62515.1 - 1e-08 34.7 70.1 0.01 15.6 2.1 11.4 12 0 0 12 12 11 8 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM62515.1 - 5.6e-06 26.3 36.8 0.44 10.6 0.1 10.2 6 3 3 10 10 10 3 Sec23/Sec24 zinc finger zinc_ribbon_15 PF17032.5 KFM62515.1 - 0.00057 20.6 49.0 0.24 12.2 2.2 6.0 1 1 5 7 7 7 5 zinc-ribbon family zf_UBZ PF18439.1 KFM62515.1 - 0.0012 18.3 54.8 2.3 7.9 0.9 11.1 11 0 0 11 11 11 2 Ubiquitin-Binding Zinc Finger Tox-HNH-HHH PF15637.6 KFM62515.1 - 0.0018 18.4 7.7 11 6.3 0.0 4.3 2 1 2 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-RRPl_C4 PF17026.5 KFM62515.1 - 0.0019 18.3 50.7 0.26 11.4 10.4 5.0 1 1 5 6 6 6 5 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_11 PF16622.5 KFM62515.1 - 0.0051 16.5 72.0 0.14 11.9 1.1 10.5 11 0 0 11 11 11 5 zinc-finger C2H2-type C1_1 PF00130.22 KFM62515.1 - 0.041 13.8 68.2 0.22 11.5 4.0 9.7 4 2 4 8 8 8 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM62515.1 - 0.28 11.0 16.7 12 5.8 0.0 6.9 3 3 5 8 8 8 0 GAGA factor Flag1_repress PF03614.13 KFM62515.1 - 0.72 9.6 5.9 6.3 6.6 0.3 3.2 2 2 1 3 3 3 0 Repressor of phase-1 flagellin DUF2256 PF10013.9 KFM62515.1 - 0.77 9.9 44.0 18 5.6 0.2 10.1 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM62515.1 - 0.88 9.6 59.4 1 9.4 5.7 8.9 5 4 5 10 10 10 0 Adenylate kinase, active site lid IGPD PF00475.18 KFM62515.1 - 2 8.7 10.8 4.8 7.5 0.1 4.7 2 2 1 5 5 5 0 Imidazoleglycerol-phosphate dehydratase Scramblase PF03803.15 KFM62515.1 - 2.3 7.5 9.7 1.5 8.0 0.9 2.8 1 1 2 3 3 3 0 Scramblase FYVE PF01363.21 KFM62515.1 - 2.6 8.3 62.5 0.68 10.1 10.6 6.7 1 1 5 7 7 7 0 FYVE zinc finger Zf_RING PF16744.5 KFM62515.1 - 2.6 8.2 55.1 17 5.6 3.1 9.9 1 1 8 10 10 10 0 KIAA1045 RING finger zf-C2HC_2 PF13913.6 KFM62515.1 - 2.7 8.0 49.9 5.1 7.1 0.2 10.6 11 0 0 11 11 11 0 zinc-finger of a C2HC-type zf-FPG_IleRS PF06827.14 KFM62515.1 - 6.7 6.7 39.8 0.66 9.9 0.2 9.5 11 0 0 11 11 11 0 Zinc finger found in FPG and IleRS zf-C2H2 PF00096.26 KFM62516.1 - 3.6e-07 30.3 5.3 6.5e-06 26.3 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM62516.1 - 5.1e-06 26.7 5.1 0.002 18.4 0.3 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM62516.1 - 2.2e-05 24.9 4.8 9.6e-05 22.9 2.3 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM62516.1 - 0.00075 19.2 2.3 0.0053 16.5 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-met PF12874.7 KFM62516.1 - 0.00081 19.7 1.7 0.00081 19.7 1.7 1.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM62516.1 - 0.0019 18.2 2.0 0.0038 17.2 2.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM62516.1 - 0.0028 17.4 1.6 0.0043 16.8 1.6 1.3 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-MYST PF17772.1 KFM62516.1 - 0.041 13.5 0.6 0.068 12.8 0.4 1.4 1 1 0 1 1 1 0 MYST family zinc finger domain BolA PF01722.18 KFM62516.1 - 0.068 13.5 0.5 0.1 12.9 0.5 1.3 1 1 0 1 1 1 0 BolA-like protein TRAF6_Z2 PF18048.1 KFM62516.1 - 0.28 11.3 1.9 6.6 6.9 0.2 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-H2C2_2 PF13465.6 KFM62517.1 - 8.8e-49 161.9 43.4 3.2e-08 33.7 0.2 8.0 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62517.1 - 9.9e-39 129.7 49.7 9.5e-07 28.9 0.8 7.2 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62517.1 - 3.6e-28 95.8 49.2 0.00026 21.6 1.7 7.2 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM62517.1 - 2.9e-17 62.4 47.0 0.0021 18.4 1.3 7.2 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM62517.1 - 5.7e-13 48.5 37.1 0.0076 16.2 1.8 6.9 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM62517.1 - 6.5e-10 39.0 35.9 0.012 15.9 0.4 6.9 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM62517.1 - 9.3e-08 31.7 31.8 0.55 10.0 0.6 7.5 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM62517.1 - 3.3e-07 30.0 19.8 1.5 8.8 0.2 6.4 6 0 0 6 6 6 4 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM62517.1 - 1.6e-06 28.1 13.2 0.27 11.3 0.0 6.2 5 1 1 6 6 6 2 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM62517.1 - 1.3e-05 25.1 13.3 0.29 11.1 1.4 4.8 1 1 6 7 7 7 5 Adenylate kinase, active site lid BolA PF01722.18 KFM62517.1 - 2.2e-05 24.7 7.4 3 8.2 0.1 4.7 1 1 3 4 4 4 3 BolA-like protein DUF2256 PF10013.9 KFM62517.1 - 0.0014 18.7 15.9 14 5.9 0.1 6.3 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 KFM62517.1 - 0.0018 17.9 24.2 0.65 9.6 0.8 6.2 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 KFM62517.1 - 0.0027 17.6 28.5 2.2 8.2 2.4 6.2 2 2 4 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_9 PF16293.5 KFM62517.1 - 0.0058 16.4 19.3 3.8 7.4 0.2 6.0 2 2 4 6 6 6 2 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KFM62517.1 - 0.0074 15.9 23.5 2.7 7.7 0.3 6.2 3 2 3 6 6 6 1 MYST family zinc finger domain zf-DBF PF07535.12 KFM62517.1 - 0.013 15.5 22.3 7.5 6.8 0.2 6.4 6 0 0 6 6 6 0 DBF zinc finger FYVE PF01363.21 KFM62517.1 - 0.016 15.3 28.2 0.045 13.9 9.5 3.9 1 1 4 5 5 5 0 FYVE zinc finger zf-RRPl_C4 PF17026.5 KFM62517.1 - 0.022 14.8 23.3 0.03 14.4 5.8 3.1 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF952 PF06108.12 KFM62517.1 - 0.025 14.6 0.1 3.3 7.8 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF952) GAGA PF09237.11 KFM62517.1 - 0.03 14.1 10.4 2.8 7.8 0.1 4.9 1 1 5 6 6 6 0 GAGA factor zf-C2H2_2 PF12756.7 KFM62517.1 - 0.034 14.5 38.6 0.88 9.9 1.4 5.8 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 KFM62517.1 - 0.094 12.8 6.5 25 5.0 0.0 5.2 6 0 0 6 6 6 0 Zinc-finger domain XPA_N PF01286.18 KFM62517.1 - 0.12 12.5 19.5 4.8 7.3 0.1 6.1 6 0 0 6 6 6 0 XPA protein N-terminal zf-HIT PF04438.16 KFM62517.1 - 0.14 12.0 24.0 13 5.7 0.3 6.3 6 0 0 6 6 6 0 HIT zinc finger zf-C2H2_11 PF16622.5 KFM62517.1 - 0.16 11.8 0.1 0.16 11.8 0.1 4.7 6 0 0 6 6 5 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFM62517.1 - 0.21 11.7 19.2 0.2 11.8 0.5 4.5 3 1 3 6 6 5 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM62517.1 - 0.22 12.3 19.2 0.93 10.3 2.4 3.3 1 1 0 3 3 3 0 zinc-ribbon family zf-Dof PF02701.15 KFM62517.1 - 0.35 11.1 15.1 0.17 12.1 0.4 4.3 2 1 3 5 5 5 0 Dof domain, zinc finger zf-BED PF02892.15 KFM62517.1 - 0.56 10.3 38.4 1 9.5 1.7 5.9 1 1 5 6 6 5 0 BED zinc finger zinc-ribbons_6 PF07191.12 KFM62517.1 - 0.61 10.1 20.1 1.8e+04 -9.2 20.1 4.9 1 1 0 1 1 0 0 zinc-ribbons zf-RRN7 PF11781.8 KFM62517.1 - 1.6 8.5 17.1 4.8 6.9 0.1 5.9 6 0 0 6 6 6 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TRAF6_Z2 PF18048.1 KFM62517.1 - 2.8 8.1 26.8 3.6 7.8 0.1 6.3 7 0 0 7 7 6 0 TNF receptor-associated factor 6 zinc finger 2 FYDLN_acid PF09538.10 KFM62517.1 - 9.3 7.0 13.5 68 4.2 0.4 5.1 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) Zn_ribbon_recom PF13408.6 KFM62518.1 - 2.6 8.6 7.7 10 6.7 5.8 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Cu2_monoox_C PF03712.15 KFM62519.1 - 5.3e-36 123.5 0.1 1e-35 122.6 0.1 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KFM62519.1 - 3.3e-25 88.8 1.4 4.6e-25 88.4 0.4 1.8 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.21 KFM62519.1 - 0.00075 19.4 0.1 0.12 12.5 0.0 3.0 2 0 0 2 2 2 1 NHL repeat RF-1 PF00472.20 KFM62523.1 - 1.7e-16 60.2 0.0 2.6e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 RF-1 domain Clathrin PF00637.20 KFM62524.1 - 3.4e-18 65.9 21.5 1.1e-15 57.8 7.2 2.7 3 0 0 3 3 3 2 Region in Clathrin and VPS hnRNP_Q_AcD PF18360.1 KFM62524.1 - 0.069 13.1 0.0 0.62 10.1 0.0 2.7 3 0 0 3 3 3 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain TPR_11 PF13414.6 KFM62524.1 - 0.073 12.8 1.0 1.4 8.7 0.0 3.4 3 0 0 3 3 3 0 TPR repeat ANAPC4_WD40 PF12894.7 KFM62524.1 - 0.079 13.3 0.0 4.2 7.7 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 KFM62524.1 - 0.093 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin TPR_12 PF13424.6 KFM62524.1 - 3.9 7.8 7.7 6 7.2 0.5 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM62524.1 - 4.8 7.5 10.7 16 5.9 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat VPS11_C PF12451.8 KFM62525.1 - 1.9e-20 72.8 0.6 1.9e-20 72.8 0.6 2.5 3 0 0 3 3 3 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.6 KFM62525.1 - 2.5e-07 30.4 8.7 4.5e-07 29.6 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM62525.1 - 7.2e-06 26.2 8.2 1.2e-05 25.5 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3H2C3 PF17122.5 KFM62525.1 - 0.00062 19.7 10.2 0.0014 18.6 10.2 1.6 1 1 0 1 1 1 1 Zinc-finger zf-rbx1 PF12678.7 KFM62525.1 - 0.0012 19.1 7.9 0.0023 18.2 7.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM62525.1 - 0.0041 17.0 7.9 0.0074 16.1 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM62525.1 - 0.0052 16.8 3.6 0.0052 16.8 3.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM62525.1 - 0.0085 16.0 8.5 0.014 15.4 8.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KFM62525.1 - 0.012 15.5 0.9 0.023 14.6 0.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4727 PF15856.5 KFM62525.1 - 0.012 15.2 0.8 0.014 15.0 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) zf-C3HC4_3 PF13920.6 KFM62525.1 - 0.021 14.7 5.0 0.032 14.1 5.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFM62525.1 - 0.027 14.6 8.6 0.057 13.6 8.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_Tnp_IS91 PF14319.6 KFM62525.1 - 0.21 11.7 6.8 0.052 13.6 3.5 1.7 1 1 1 2 2 2 0 Transposase zinc-binding domain Prok-RING_4 PF14447.6 KFM62525.1 - 0.21 11.5 6.1 0.43 10.5 6.1 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 KFM62525.1 - 0.24 11.7 9.1 0.66 10.3 9.1 1.7 1 1 0 1 1 1 0 RING-like domain DLP_helical PF18709.1 KFM62525.1 - 0.49 9.6 3.1 1.6 7.9 2.1 1.9 2 0 0 2 2 2 0 Dynamin-like helical domain DUF4379 PF14311.6 KFM62525.1 - 0.57 10.6 2.7 18 5.8 0.0 2.3 2 0 0 2 2 2 0 Probable Zinc-ribbon domain Vps39_2 PF10367.9 KFM62525.1 - 2.4 8.7 7.0 0.33 11.4 2.4 1.9 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 KFM62525.1 - 6.3 6.6 10.9 20 5.0 7.2 3.0 2 1 1 3 3 3 0 RING-like zinc finger zf-C2H2_jaz PF12171.8 KFM62526.1 - 7.6e-07 29.3 26.8 0.013 15.8 0.4 4.9 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM62526.1 - 0.0015 18.8 22.7 0.46 10.9 0.7 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-U1 PF06220.12 KFM62526.1 - 0.021 14.6 3.3 0.021 14.6 3.3 2.5 2 0 0 2 2 2 0 U1 zinc finger zf-C2H2_2 PF12756.7 KFM62526.1 - 0.1 12.9 22.0 0.13 12.6 0.9 4.4 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) SMC_N PF02463.19 KFM62527.1 - 2.3e-06 27.2 0.0 2.4e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFM62527.1 - 0.0015 19.1 0.0 0.0016 19.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KFM62527.1 - 0.0049 16.6 0.1 0.0056 16.4 0.1 1.0 1 0 0 1 1 1 1 AAA ATPase domain F-box_4 PF15966.5 KFM62529.1 - 0.041 13.8 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 F-box zf-TRAF_2 PF15965.5 KFM62530.1 - 1.9e-35 121.2 15.3 1.9e-35 121.2 15.3 3.2 4 0 0 4 4 4 1 TRAF-like zinc-finger Nucleotid_trans PF03407.16 KFM62530.1 - 0.0069 16.4 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Rac1 PF09632.10 KFM62530.1 - 0.15 11.2 1.0 0.23 10.6 1.0 1.2 1 0 0 1 1 1 0 Rac1-binding domain BBS2_C PF14782.6 KFM62531.1 - 6.3e-82 275.6 0.0 1.1e-81 274.8 0.0 1.4 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 KFM62531.1 - 3.9e-43 145.9 0.2 4.8e-41 139.2 0.1 2.5 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 KFM62531.1 - 2.6e-40 136.5 0.0 1.1e-39 134.6 0.0 2.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal FG-GAP PF01839.23 KFM62531.1 - 1.8e-07 31.2 1.3 0.021 14.9 0.1 2.8 2 0 0 2 2 2 2 FG-GAP repeat Itfg2 PF15907.5 KFM62531.1 - 1.8e-05 23.9 0.4 2.6 7.0 0.0 4.0 1 1 2 3 3 3 3 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 KFM62531.1 - 0.00024 21.6 4.3 0.016 15.8 1.2 3.5 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_C PF14782.6 KFM62532.1 - 2.8e-08 33.0 0.2 2.8e-08 33.0 0.2 1.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_C PF14782.6 KFM62533.1 - 1.7e-44 152.3 5.6 1.9e-44 152.1 5.6 1.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal DUF4477 PF14780.6 KFM62533.1 - 0.052 13.2 0.7 0.075 12.7 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4477) C2 PF00168.30 KFM62534.1 - 1.2e-09 38.4 0.0 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 KFM62535.1 - 7.8e-50 168.8 0.3 1.1e-49 168.3 0.3 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KFM62535.1 - 0.0008 19.7 0.0 0.061 13.6 0.0 2.6 2 1 0 2 2 2 1 C2 domain DUF3918 PF13056.6 KFM62535.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) HTH_Tnp_Tc3_2 PF01498.18 KFM62536.1 - 2.5e-06 27.7 0.0 4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Transposase PWWP PF00855.17 KFM62538.1 - 9.2e-17 61.2 1.4 1.7e-16 60.4 1.4 1.5 1 0 0 1 1 1 1 PWWP domain Nif11 PF07862.11 KFM62538.1 - 0.039 14.2 0.1 0.16 12.3 0.0 1.9 2 1 0 2 2 2 0 Nif11 domain SET PF00856.28 KFM62539.1 - 1.6e-21 77.5 3.9 2.5e-21 76.8 0.1 3.1 2 2 1 3 3 3 1 SET domain PWWP PF00855.17 KFM62539.1 - 1.8e-18 66.7 0.0 1.8e-18 66.7 0.0 2.2 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 KFM62539.1 - 1.9e-14 53.3 96.3 0.00034 20.5 5.5 9.3 5 3 3 8 8 8 5 PHD-finger AWS PF17907.1 KFM62539.1 - 6.5e-12 45.3 5.8 6.5e-12 45.3 5.8 4.7 3 1 0 3 3 3 1 AWS domain C5HCH PF17982.1 KFM62539.1 - 1.1e-08 35.1 42.7 2.9e-05 24.1 8.4 7.3 6 2 1 7 7 7 3 NSD Cys-His rich domain zf-HC5HC2H_2 PF13832.6 KFM62539.1 - 8.7e-06 25.9 9.5 0.00041 20.5 1.2 7.1 5 2 1 6 6 6 4 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFM62539.1 - 0.017 15.4 4.4 0.017 15.4 4.4 8.7 6 3 0 7 7 7 0 PHD-like zinc-binding domain XK-related PF09815.9 KFM62542.1 - 2.5e-99 332.6 30.5 2.8e-99 332.4 30.5 1.0 1 0 0 1 1 1 1 XK-related protein UCH PF00443.29 KFM62543.1 - 7.1e-50 169.9 0.5 1.3e-49 169.0 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM62543.1 - 1.5e-29 103.6 0.2 3.6e-28 99.1 0.2 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-H2C2_2 PF13465.6 KFM62543.1 - 0.16 12.4 4.9 2.4 8.7 0.6 3.0 2 0 0 2 2 2 0 Zinc-finger double domain DZR PF12773.7 KFM62543.1 - 0.47 10.5 4.6 0.53 10.4 0.4 2.6 2 0 0 2 2 2 0 Double zinc ribbon HTH_48 PF17906.1 KFM62545.1 - 3.4e-07 30.3 0.0 2.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 HTH domain in Mos1 transposase mit_SMPDase PF14724.6 KFM62546.1 - 0.01 13.9 0.1 0.011 13.8 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase DUF478 PF04334.12 KFM62546.1 - 0.17 12.0 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF478) gag-asp_proteas PF13975.6 KFM62548.1 - 8.1e-13 48.8 0.1 3.2e-12 46.9 0.0 2.1 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM62548.1 - 3.3e-11 43.7 0.0 9.7e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease HSBP1 PF06825.12 KFM62548.1 - 0.00055 19.7 0.9 0.24 11.3 0.1 3.2 2 1 1 3 3 3 1 Heat shock factor binding protein 1 Peptidase_M75 PF09375.10 KFM62548.1 - 0.001 18.6 2.3 0.0031 17.0 2.3 1.8 1 0 0 1 1 1 1 Imelysin Asp_protease PF09668.10 KFM62548.1 - 0.0011 18.7 0.4 0.0057 16.5 0.0 2.3 2 1 0 2 2 2 1 Aspartyl protease Baculo_PEP_C PF04513.12 KFM62548.1 - 0.002 18.2 2.6 0.23 11.5 0.3 3.7 3 1 1 4 4 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus PNMA PF14893.6 KFM62548.1 - 0.0053 16.2 0.1 0.0053 16.2 0.1 2.3 2 0 0 2 2 2 1 PNMA Peptidase_S64 PF08192.11 KFM62548.1 - 0.0062 15.1 5.9 0.011 14.2 5.9 1.3 1 0 0 1 1 1 1 Peptidase family S64 RVP PF00077.20 KFM62548.1 - 0.039 14.3 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 Retroviral aspartyl protease NPV_P10 PF05531.12 KFM62548.1 - 0.039 14.4 8.7 0.5 10.9 1.6 3.8 3 1 2 6 6 5 0 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.18 KFM62548.1 - 0.083 12.8 22.8 0.075 12.9 13.1 4.0 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain RVP_2 PF08284.11 KFM62548.1 - 0.094 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease FAD_SOX PF18371.1 KFM62548.1 - 0.095 13.1 1.7 5.6 7.4 0.0 3.2 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase MLVIN_C PF18697.1 KFM62548.1 - 0.097 12.8 0.1 0.28 11.3 0.1 1.8 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain ABC_tran_CTD PF16326.5 KFM62548.1 - 0.12 12.6 0.1 0.12 12.6 0.1 3.9 6 0 0 6 6 2 0 ABC transporter C-terminal domain DUF3994 PF13159.6 KFM62548.1 - 0.15 12.7 3.1 0.42 11.2 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3994) DUF1640 PF07798.11 KFM62548.1 - 0.24 11.5 22.4 0.02 14.9 14.7 3.1 3 1 0 3 3 2 0 Protein of unknown function (DUF1640) DUF948 PF06103.11 KFM62548.1 - 0.26 11.6 4.2 3.5 7.9 0.5 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SF-assemblin PF06705.11 KFM62548.1 - 0.27 10.5 15.8 1.7 8.0 15.3 2.2 1 1 0 1 1 1 0 SF-assemblin/beta giardin DUF4407 PF14362.6 KFM62548.1 - 0.48 9.7 8.1 5.2 6.3 7.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4238 PF14022.6 KFM62548.1 - 0.52 9.8 3.1 1.6 8.2 3.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) Prominin PF05478.11 KFM62548.1 - 0.68 7.8 9.8 2.3 6.0 4.0 2.4 1 1 1 2 2 2 0 Prominin FliG_M PF14841.6 KFM62548.1 - 0.79 10.0 6.8 3.8 7.8 0.1 3.9 3 1 1 4 4 4 0 FliG middle domain TPR_MLP1_2 PF07926.12 KFM62548.1 - 1.1 9.3 16.5 0.046 13.8 8.9 2.7 3 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein Osmo_CC PF08946.10 KFM62548.1 - 1.2 9.5 6.6 7 7.0 1.0 3.6 2 1 1 3 3 3 0 Osmosensory transporter coiled coil Spore_III_AB PF09548.10 KFM62548.1 - 1.2 9.2 8.8 3 7.9 8.8 1.7 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Spectrin PF00435.21 KFM62548.1 - 1.4 9.5 12.5 7.3 7.1 2.2 3.7 2 1 1 3 3 3 0 Spectrin repeat CAF-1_p150 PF11600.8 KFM62548.1 - 1.9 8.2 20.1 6.1 6.5 20.1 1.9 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1664 PF07889.12 KFM62548.1 - 2.4 8.2 17.9 2 8.5 8.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Med8 PF10232.9 KFM62548.1 - 2.5 7.6 0.0 2.5 7.6 0.0 3.0 2 1 1 3 3 2 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF148 PF02520.17 KFM62548.1 - 6 7.0 13.6 13 6.0 7.4 3.4 2 1 1 3 3 3 0 Domain of unknown function DUF148 BCAS2 PF05700.11 KFM62548.1 - 6.9 6.3 9.1 6.1 6.5 6.5 2.2 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Prefoldin_3 PF13758.6 KFM62548.1 - 7.2 6.7 13.0 20 5.3 6.5 3.0 2 1 0 3 3 2 0 Prefoldin subunit XhlA PF10779.9 KFM62548.1 - 8.7 6.6 10.1 0.76 10.0 0.7 3.7 3 2 0 3 3 3 0 Haemolysin XhlA WXG100 PF06013.12 KFM62548.1 - 9.1 6.6 11.5 39 4.6 5.3 3.9 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF4158 PF13700.6 KFM62549.1 - 0.0065 16.3 0.2 0.57 10.0 0.0 3.0 2 2 0 3 3 3 1 Domain of unknown function (DUF4158) Glyco_tranf_2_4 PF13704.6 KFM62549.1 - 0.041 14.4 1.7 0.51 10.9 0.4 2.2 1 1 1 2 2 2 0 Glycosyl transferase family 2 FAST_1 PF06743.15 KFM62549.1 - 0.078 12.9 0.1 0.25 11.3 0.1 1.9 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 DUF4116 PF13475.6 KFM62549.1 - 0.13 12.0 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF5087 PF17006.5 KFM62551.1 - 0.048 13.2 1.0 0.068 12.7 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5087) CRISPR_Cas2 PF09827.9 KFM62551.1 - 0.072 13.3 0.2 0.21 11.8 0.2 1.8 1 0 0 1 1 1 0 CRISPR associated protein Cas2 WbqC PF08889.11 KFM62551.1 - 0.082 12.8 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 WbqC-like protein family CPSase_L_D2 PF02786.17 KFM62552.1 - 3e-81 271.9 0.1 7.4e-81 270.7 0.1 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFM62552.1 - 9.1e-46 154.9 0.0 1.7e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFM62552.1 - 3e-33 114.1 0.0 7.5e-33 112.9 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 KFM62552.1 - 6.6e-26 91.1 0.0 1.9e-25 89.7 0.0 1.8 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 KFM62552.1 - 1.9e-15 56.4 3.8 5.4e-15 55.0 3.8 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KFM62552.1 - 4.8e-09 36.0 0.0 9.3e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFM62552.1 - 3.1e-08 33.4 0.1 9.8e-08 31.8 0.0 1.8 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KFM62552.1 - 4.9e-06 26.3 0.0 0.023 14.5 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.11 KFM62552.1 - 3.7e-05 23.4 0.0 0.00014 21.5 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KFM62552.1 - 0.00018 21.6 0.1 0.00039 20.5 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KFM62552.1 - 0.003 17.3 0.1 0.0079 15.9 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KFM62552.1 - 0.022 14.2 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 KFM62552.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Nif11 PF07862.11 KFM62552.1 - 0.052 13.9 0.0 7.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Nif11 domain Kelch_6 PF13964.6 KFM62553.1 - 1.7e-19 69.3 1.2 4.1e-07 30.1 0.0 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 KFM62553.1 - 2.6e-16 58.9 1.1 4.7e-06 26.1 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 KFM62553.1 - 8.7e-15 54.5 5.0 2.1e-06 27.6 0.0 3.3 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFM62553.1 - 1.7e-12 46.8 5.7 0.0045 16.9 0.3 3.6 3 1 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 KFM62553.1 - 2e-12 46.8 2.6 0.001 19.0 0.0 3.5 3 1 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 KFM62553.1 - 5.6e-12 45.6 1.9 1.7e-05 24.9 0.0 3.4 4 0 0 4 4 4 2 Galactose oxidase, central domain HTH_Tnp_Tc3_2 PF01498.18 KFM62554.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62554.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HMG_box PF00505.19 KFM62555.1 - 5.2e-26 90.8 4.2 1.1e-25 89.8 4.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM62555.1 - 7.9e-10 39.2 3.3 1.8e-09 38.1 2.7 2.0 2 0 0 2 2 2 1 HMG-box domain TPR_11 PF13414.6 KFM62557.1 - 0.0003 20.4 0.7 0.00062 19.4 0.4 1.6 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.6 KFM62557.1 - 0.065 13.1 0.1 0.096 12.6 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DDE_1 PF03184.19 KFM62558.1 - 1e-29 103.4 0.3 1.7e-29 102.7 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM62558.1 - 3.6e-11 42.9 0.2 3.6e-11 42.9 0.2 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain BrkDBD PF09607.10 KFM62558.1 - 5.9e-09 35.6 0.3 1.7e-08 34.1 0.3 1.7 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_1 PF01527.20 KFM62558.1 - 0.00067 19.9 3.1 0.00067 19.9 3.1 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62558.1 - 0.0075 16.0 0.0 0.084 12.6 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease LolA PF03548.15 KFM62558.1 - 0.021 14.5 0.1 0.059 13.1 0.0 1.8 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA HMG_box PF00505.19 KFM62559.1 - 7.2e-12 45.6 0.1 8.9e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM62559.1 - 4.8e-05 23.9 0.0 7.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain His_Phos_1 PF00300.22 KFM62560.1 - 4.8e-15 55.8 0.0 1.4e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) EMP70 PF02990.16 KFM62561.1 - 0.039 12.6 0.7 0.046 12.4 0.7 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 NMN_transporter PF04973.12 KFM62561.1 - 0.073 13.0 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DUF872 PF05915.12 KFM62561.1 - 0.091 12.9 0.6 0.091 12.9 0.6 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Cyt_bd_oxida_II PF02322.15 KFM62561.1 - 0.14 11.5 1.8 0.19 11.1 1.7 1.3 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Glycos_transf_4 PF00953.21 KFM62561.1 - 0.17 11.9 2.4 0.3 11.0 2.4 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 4 Tetraspanin PF00335.20 KFM62561.1 - 0.25 11.0 7.0 0.48 10.1 7.0 1.5 1 1 0 1 1 1 0 Tetraspanin family CD20 PF04103.15 KFM62561.1 - 0.27 11.3 7.0 1.1 9.3 7.2 1.9 1 1 1 2 2 2 0 CD20-like family FAM70 PF14967.6 KFM62561.1 - 0.28 10.6 5.9 0.4 10.1 5.8 1.3 1 1 0 1 1 1 0 FAM70 protein DUF308 PF03729.13 KFM62561.1 - 0.44 10.9 9.2 0.77 10.1 0.8 3.2 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF1218 PF06749.12 KFM62561.1 - 1.3 9.6 6.9 3.6 8.2 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) WD40 PF00400.32 KFM62562.1 - 2.4e-11 44.0 0.9 0.006 17.4 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM62562.1 - 1.1e-06 28.8 0.0 0.36 11.2 0.0 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF687 PF05095.12 KFM62565.1 - 0.028 13.0 0.0 0.03 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF687) AAA PF00004.29 KFM62566.1 - 4e-11 43.5 0.0 6.8e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFM62566.1 - 0.023 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RuvB_N PF05496.12 KFM62566.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KFM62566.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KFM62566.1 - 0.11 12.9 0.1 0.45 10.9 0.1 2.0 1 1 0 1 1 1 0 RNA helicase LIM_bind PF01803.16 KFM62566.1 - 0.19 11.3 0.2 0.24 10.9 0.2 1.1 1 0 0 1 1 1 0 LIM-domain binding protein AP3D1 PF06375.11 KFM62566.1 - 1.7 8.8 6.9 2.7 8.2 6.9 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 YAcAr PF10686.9 KFM62570.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Transcrip_reg PF01709.20 KFM62572.1 - 3.9e-25 88.7 0.0 5.3e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator DOCK-C2 PF14429.6 KFM62574.1 - 1.6e-12 47.6 1.2 2.9e-12 46.8 0.2 2.0 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins PH_17 PF18012.1 KFM62574.1 - 9e-05 22.1 0.1 0.00021 20.9 0.1 1.6 1 0 0 1 1 1 1 PH domain PH PF00169.29 KFM62574.1 - 0.00082 19.9 0.2 0.0034 17.9 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KFM62574.1 - 0.0018 18.7 0.0 0.0045 17.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain ECH_1 PF00378.20 KFM62575.1 - 8.4e-42 143.2 0.0 9.5e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM62575.1 - 8.9e-19 68.2 0.1 2.3e-18 66.8 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFM62575.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 2 0 0 2 2 2 0 Peptidase family S49 Inhibitor_I78 PF11720.8 KFM62576.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I78 family CRAL_TRIO PF00650.20 KFM62577.1 - 1.1e-08 34.9 0.0 1.2e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM62579.1 - 1.2e-06 28.4 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM62579.1 - 0.00048 20.6 0.0 0.0011 19.4 0.0 1.6 1 1 1 2 2 2 1 Golgi-dynamics membrane-trafficking CRAL_TRIO PF00650.20 KFM62580.1 - 3.5e-07 30.1 0.0 3.7e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM62581.1 - 0.00061 19.9 0.9 0.00078 19.6 0.9 1.3 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain TrmK PF04816.12 KFM62581.1 - 0.092 12.3 0.3 0.096 12.2 0.3 1.0 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase CRAL_TRIO PF00650.20 KFM62583.1 - 1.2e-28 99.8 0.1 1.8e-28 99.2 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM62583.1 - 2.5e-08 34.5 0.0 0.0014 19.2 0.0 2.5 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 KFM62583.1 - 0.014 15.6 0.3 0.038 14.2 0.3 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM62583.1 - 0.027 14.6 0.1 0.08 13.1 0.0 1.8 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain SBP56 PF05694.11 KFM62584.1 - 7e-184 611.9 0.1 8e-184 611.7 0.1 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFM62584.1 - 5.1e-05 22.7 0.0 0.00079 18.8 0.0 2.6 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller DUF5557 PF17712.1 KFM62584.1 - 0.091 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5557) GOLD_2 PF13897.6 KFM62585.1 - 4.9e-07 30.3 0.3 9.6e-05 22.9 0.5 2.1 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO PF00650.20 KFM62586.1 - 1.8e-16 60.2 0.0 1.9e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM62586.1 - 0.0045 17.1 0.1 0.005 17.0 0.1 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RAP80_UIM PF18282.1 KFM62588.1 - 1.4 8.8 3.4 1.3 8.8 0.9 2.0 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif HTH_23 PF13384.6 KFM62590.1 - 6.5e-08 32.2 0.0 7.8e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KFM62590.1 - 1.7e-06 27.6 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 KFM62590.1 - 3.8e-06 26.8 0.1 4.9e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_50 PF18024.1 KFM62590.1 - 1.7e-05 24.3 0.2 2.3e-05 23.9 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KFM62590.1 - 1.9e-05 24.3 0.1 2.7e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KFM62590.1 - 2.9e-05 24.1 0.0 3.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM62590.1 - 9.4e-05 21.7 0.0 0.00011 21.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 UPF0122 PF04297.14 KFM62590.1 - 0.00052 20.2 0.0 0.00059 20.0 0.0 1.1 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.16 KFM62590.1 - 0.0018 17.8 0.1 0.0021 17.5 0.1 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_IS630 PF01710.16 KFM62590.1 - 0.0023 18.0 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_24 PF13412.6 KFM62590.1 - 0.0049 16.4 0.1 0.0057 16.2 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_7 PF02796.15 KFM62590.1 - 0.0088 16.1 0.1 0.015 15.3 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_1 PF00126.27 KFM62590.1 - 0.011 15.6 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Mor PF08765.11 KFM62590.1 - 0.012 15.6 0.3 0.014 15.4 0.3 1.2 1 0 0 1 1 1 0 Mor transcription activator family TnsD PF15978.5 KFM62590.1 - 0.013 14.6 0.1 0.013 14.6 0.1 1.0 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_Tnp_1 PF01527.20 KFM62590.1 - 0.014 15.7 0.0 0.015 15.6 0.0 1.1 1 0 0 1 1 1 0 Transposase HTH_40 PF14493.6 KFM62590.1 - 0.038 14.4 0.1 0.042 14.3 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_46 PF15977.5 KFM62590.1 - 0.077 13.0 0.2 0.1 12.6 0.2 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DNA binding TrmB PF01978.19 KFM62590.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2427 PF10348.9 KFM62592.1 - 3.5 7.5 5.5 5.5 6.8 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Ig_3 PF13927.6 KFM62594.1 - 1.3e-39 134.6 6.1 2.3e-07 31.3 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 KFM62594.1 - 5.1e-29 100.4 8.2 5.7e-06 26.6 0.1 5.8 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFM62594.1 - 6.2e-26 90.3 1.8 3.9e-05 23.6 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin I-set domain ig PF00047.25 KFM62594.1 - 8.5e-26 90.0 8.9 2.4e-06 27.6 0.6 5.5 5 0 0 5 5 5 5 Immunoglobulin domain C2-set_2 PF08205.12 KFM62594.1 - 1.2e-15 57.4 1.5 2e-08 34.2 0.0 3.3 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM62594.1 - 3.2e-10 40.2 10.4 5.8e-09 36.1 0.2 5.4 5 1 1 6 6 6 1 Immunoglobulin V-set domain C1-set PF07654.15 KFM62594.1 - 1.6e-05 25.2 2.2 0.8 10.1 0.2 4.5 4 0 0 4 4 4 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFM62594.1 - 0.00024 20.6 0.2 0.076 12.6 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.5 KFM62594.1 - 0.00056 20.1 3.2 4.2 7.7 0.1 4.1 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFM62594.1 - 0.00066 19.7 7.9 0.038 14.0 0.8 4.1 3 1 1 4 4 4 1 CD47 immunoglobulin-like domain Izumo-Ig PF16706.5 KFM62594.1 - 0.0041 17.2 0.8 0.26 11.4 0.0 3.3 2 1 1 3 3 3 1 Izumo-like Immunoglobulin domain TIR_2 PF13676.6 KFM62595.1 - 0.00045 20.8 0.5 0.0016 19.1 0.1 1.9 2 0 0 2 2 2 1 TIR domain Peptidase_C1 PF00112.23 KFM62596.1 - 4e-65 220.0 0.8 4e-65 220.0 0.8 1.6 2 0 0 2 2 2 1 Papain family cysteine protease CathepsinC_exc PF08773.11 KFM62596.1 - 7.3e-44 148.9 2.3 1.5e-43 147.9 2.3 1.5 1 0 0 1 1 1 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 KFM62596.1 - 1.7e-06 27.1 1.8 2.1e-05 23.5 0.4 2.2 2 0 0 2 2 2 1 Peptidase C1-like family Propeptide_C1 PF08127.13 KFM62596.1 - 0.043 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide B_solenoid_dext PF18841.1 KFM62596.1 - 0.088 13.1 0.9 0.21 11.9 0.9 1.7 1 0 0 1 1 1 0 Beta solenoid repeat from Dextranase RLI PF04068.15 KFM62596.1 - 2.9 7.8 5.8 10 6.1 5.8 2.0 1 1 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI Peptidase_C1 PF00112.23 KFM62597.1 - 4e-64 216.7 0.3 4e-64 216.7 0.3 1.6 2 0 0 2 2 2 1 Papain family cysteine protease CathepsinC_exc PF08773.11 KFM62597.1 - 2.6e-42 143.9 0.5 5e-42 143.0 0.5 1.5 1 0 0 1 1 1 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 KFM62597.1 - 1.5e-05 24.0 0.8 0.0017 17.2 0.2 2.4 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 KFM62597.1 - 0.0097 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide 6PF2K PF01591.18 KFM62598.1 - 2.2e-89 298.6 0.3 3e-89 298.1 0.3 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFM62598.1 - 1.4e-41 142.3 0.2 3.3e-41 141.1 0.1 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFM62598.1 - 4.6e-05 23.6 0.0 9.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain rve PF00665.26 KFM62598.1 - 0.0055 16.9 0.1 11 6.3 0.0 3.3 3 0 0 3 3 3 2 Integrase core domain KTI12 PF08433.10 KFM62598.1 - 0.024 14.1 0.1 0.086 12.3 0.1 1.8 1 1 0 1 1 1 0 Chromatin associated protein KTI12 TAP_C PF03943.13 KFM62598.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain Terminase_GpA PF05876.12 KFM62598.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Phasin PF05597.11 KFM62599.1 - 0.033 14.2 1.0 0.29 11.1 1.0 2.1 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GAIN PF16489.5 KFM62600.1 - 2.2e-16 59.9 0.2 2.2e-16 59.9 0.2 1.8 2 0 0 2 2 2 1 GPCR-Autoproteolysis INducing (GAIN) domain HRM PF02793.22 KFM62600.1 - 2.5e-06 27.7 0.7 6.2e-06 26.4 0.7 1.7 1 0 0 1 1 1 1 Hormone receptor domain MRVI1 PF05781.12 KFM62604.1 - 2.8e-20 72.5 0.3 3.3e-20 72.3 0.3 1.0 1 0 0 1 1 1 1 MRVI1 protein DUF3450 PF11932.8 KFM62604.1 - 0.03 13.6 0.2 0.031 13.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CspB_prodomain PF18425.1 KFM62604.1 - 0.098 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Csp protease B prodomain DNAPolymera_Pol PF11590.8 KFM62604.1 - 1.1 9.2 5.6 1.1 9.2 1.6 2.5 2 1 0 2 2 2 0 DNA polymerase catalytic subunit Pol Toxin_9 PF02819.15 KFM62607.1 - 2e-05 24.7 15.2 2.8e-05 24.3 15.2 1.2 1 0 0 1 1 1 1 Spider toxin Agouti PF05039.12 KFM62607.1 - 0.027 15.2 8.6 0.03 15.0 8.6 1.2 1 0 0 1 1 1 0 Agouti protein Toxin_35 PF10530.9 KFM62607.1 - 0.8 9.7 17.9 2.5 8.1 17.9 1.7 1 1 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold DDE_3 PF13358.6 KFM62609.1 - 5.9e-16 58.5 0.1 6.7e-15 55.1 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62609.1 - 7.6e-16 58.1 6.5 1.6e-15 57.1 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM62609.1 - 0.0008 20.0 1.5 0.0008 20.0 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM62609.1 - 0.003 17.3 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62609.1 - 0.015 15.4 0.5 0.071 13.2 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM62609.1 - 0.039 14.0 0.4 0.039 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix p450 PF00067.22 KFM62610.1 - 2.3e-39 135.4 0.2 2.6e-39 135.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phytase PF02333.15 KFM62610.1 - 0.064 12.2 0.0 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 Phytase QVR PF17064.5 KFM62611.1 - 2.1e-16 59.9 3.3 2.7e-16 59.6 3.3 1.1 1 0 0 1 1 1 1 Sleepless protein Activin_recp PF01064.23 KFM62611.1 - 0.036 15.1 4.0 0.067 14.3 4.1 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain DUF753 PF05444.12 KFM62611.1 - 0.35 10.9 4.1 0.35 10.9 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF753) LEAP-2 PF07359.11 KFM62612.1 - 0.00065 19.5 0.1 0.92 9.4 0.0 2.4 2 1 0 2 2 2 2 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) DDE_Tnp_1_7 PF13843.6 KFM62613.1 - 1.1e-14 54.6 0.0 1.2e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Ank_2 PF12796.7 KFM62614.1 - 6.6e-51 170.8 3.8 1.3e-15 57.8 0.0 6.2 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM62614.1 - 5.5e-43 140.0 12.0 5.2e-06 26.4 0.1 10.7 10 1 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 KFM62614.1 - 3.3e-42 141.1 11.6 2e-07 31.1 0.0 8.9 7 1 1 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 KFM62614.1 - 6.6e-42 141.4 11.2 1e-11 45.1 0.3 8.5 3 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM62614.1 - 2.5e-32 110.5 8.1 9.4e-06 25.8 0.1 8.7 4 2 5 9 9 9 8 Ankyrin repeats (many copies) TPR_12 PF13424.6 KFM62614.1 - 0.014 15.6 0.3 0.78 10.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM62614.1 - 0.11 12.4 0.1 2.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM62614.1 - 0.18 12.0 2.3 3.9 7.8 1.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM62614.1 - 0.56 10.2 3.9 1.1 9.2 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 KFM62615.1 - 2.7e-67 222.7 3.5 2.5e-21 75.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HTH_Tnp_Tc3_2 PF01498.18 KFM62616.1 - 3.6e-16 59.1 3.0 6.3e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62616.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62616.1 - 2.9e-07 30.1 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62616.1 - 0.0029 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62616.1 - 2.8 8.6 15.6 0.13 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62617.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62617.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Dynamin_M PF01031.20 KFM62618.1 - 0.013 14.8 3.6 0.053 12.7 0.6 2.2 2 0 0 2 2 2 0 Dynamin central region Tup_N PF08581.10 KFM62618.1 - 0.024 14.9 6.5 0.43 10.9 1.4 2.7 2 1 0 2 2 2 0 Tup N-terminal Spore_III_AB PF09548.10 KFM62618.1 - 0.027 14.6 2.1 0.046 13.8 0.2 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF2203 PF09969.9 KFM62618.1 - 0.033 14.9 2.8 0.29 11.9 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ribosomal_S15 PF00312.22 KFM62618.1 - 0.057 13.6 1.7 0.057 13.6 1.7 1.7 2 0 0 2 2 2 0 Ribosomal protein S15 KxDL PF10241.9 KFM62618.1 - 0.078 13.3 5.5 0.69 10.2 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein IF-2B PF01008.17 KFM62618.1 - 0.085 12.1 1.8 5.3 6.2 0.2 2.0 2 0 0 2 2 2 0 Initiation factor 2 subunit family LPP PF04728.13 KFM62618.1 - 0.094 13.1 3.2 25 5.4 0.3 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper NPV_P10 PF05531.12 KFM62618.1 - 0.1 13.1 3.8 2 8.9 0.0 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1843 PF08898.10 KFM62618.1 - 0.11 13.0 1.2 0.48 11.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF4709 PF15821.5 KFM62618.1 - 0.58 10.5 8.7 0.57 10.5 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) IFT57 PF10498.9 KFM62618.1 - 1.2 8.0 9.3 0.69 8.8 4.5 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 YojJ PF10372.9 KFM62618.1 - 2.1 8.5 5.5 3.7 7.7 0.2 3.5 2 2 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus ZapB PF06005.12 KFM62618.1 - 3.2 8.3 9.6 1.3 9.5 0.9 2.6 2 1 0 2 2 2 0 Cell division protein ZapB Myb_DNA-bind_4 PF13837.6 KFM62619.1 - 1.4e-14 54.2 0.2 1.4e-14 54.2 0.2 3.1 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KFM62619.1 - 0.005 17.8 1.1 0.027 15.4 0.1 2.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM62619.1 - 0.01 16.1 0.1 0.01 16.1 0.1 3.5 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HisKA PF00512.25 KFM62619.1 - 2.5 8.2 7.9 19 5.3 0.4 3.5 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Spectrin PF00435.21 KFM62620.1 - 0.0034 17.9 6.8 0.039 14.4 6.2 2.2 1 1 0 1 1 1 1 Spectrin repeat Cep57_MT_bd PF06657.13 KFM62620.1 - 0.026 15.0 3.1 0.03 14.8 1.2 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.8 KFM62620.1 - 0.035 14.2 4.6 0.053 13.6 4.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding AhpC-TSA PF00578.21 KFM62620.1 - 0.051 13.5 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family DUF1825 PF08855.10 KFM62620.1 - 0.053 13.4 1.9 0.11 12.5 1.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) T3SS_needle_F PF09392.10 KFM62620.1 - 0.11 12.7 1.0 0.25 11.5 0.8 1.7 1 1 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF ZapB PF06005.12 KFM62620.1 - 0.7 10.4 11.0 3.4 8.2 8.2 2.7 2 1 0 2 2 2 0 Cell division protein ZapB DDE_3 PF13358.6 KFM62621.1 - 2.5e-16 59.7 0.1 2.9e-15 56.3 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62621.1 - 1.4e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase CheR_N PF03705.15 KFM62622.1 - 0.04 13.6 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain RVT_1 PF00078.27 KFM62623.1 - 1.6e-31 109.6 0.0 3.7e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 KFM62623.1 - 1.3e-12 48.1 0.2 4.3e-12 46.4 0.0 2.1 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM62623.1 - 3.3e-10 40.5 0.0 8.2e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Apolipoprotein PF01442.18 KFM62623.1 - 5.3e-09 36.2 23.2 5.3e-09 36.2 23.2 3.3 4 0 0 4 4 3 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM62623.1 - 9.5e-06 25.7 6.4 0.0011 19.0 1.0 3.9 2 1 1 3 3 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 KFM62623.1 - 0.00014 21.7 9.4 2 8.3 0.2 4.9 5 0 0 5 5 5 3 Heat shock factor binding protein 1 Asp_protease PF09668.10 KFM62623.1 - 0.0006 19.6 0.1 0.0029 17.4 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease DUF3584 PF12128.8 KFM62623.1 - 0.0074 13.9 23.4 0.016 12.7 23.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Phasin PF05597.11 KFM62623.1 - 0.067 13.2 36.7 10 6.1 15.0 5.0 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 KFM62623.1 - 0.082 13.0 31.2 0.048 13.7 9.7 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 KFM62623.1 - 0.28 11.2 37.3 0.048 13.7 13.3 3.3 3 1 1 4 4 2 0 Protein of unknown function (DUF1640) Prominin PF05478.11 KFM62623.1 - 0.33 8.8 22.4 0.59 8.0 13.1 2.4 1 1 1 2 2 2 0 Prominin ApoO PF09769.9 KFM62623.1 - 0.45 10.5 13.7 3.7 7.5 3.1 4.1 1 1 1 2 2 2 0 Apolipoprotein O Peptidase_S64 PF08192.11 KFM62623.1 - 0.69 8.3 20.2 1.5 7.2 20.2 1.5 1 0 0 1 1 1 0 Peptidase family S64 Cache_3-Cache_2 PF17201.4 KFM62623.1 - 1.3 8.2 16.3 2.3 7.4 4.9 3.1 3 0 0 3 3 3 0 Cache 3/Cache 2 fusion domain HalX PF08663.10 KFM62623.1 - 1.4 9.3 6.7 15 6.0 0.3 4.0 3 1 1 4 4 2 0 HalX domain Tnp_22_trimer PF17489.2 KFM62623.1 - 1.7 8.7 16.9 1 9.4 0.4 5.3 2 1 3 5 5 5 0 L1 transposable element trimerization domain DUF883 PF05957.13 KFM62623.1 - 1.9 9.2 24.9 2 9.1 5.6 4.4 2 1 1 4 4 3 0 Bacterial protein of unknown function (DUF883) GPW_gp25 PF04965.14 KFM62623.1 - 1.9 8.3 4.9 2 8.2 1.4 2.8 2 1 1 3 3 3 0 Gene 25-like lysozyme DUF4407 PF14362.6 KFM62623.1 - 2.6 7.3 17.5 11 5.3 17.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_32 PF13654.6 KFM62623.1 - 3 6.5 24.1 7.3 5.3 24.1 1.6 1 0 0 1 1 1 0 AAA domain ApoLp-III PF07464.11 KFM62623.1 - 4.8 7.3 39.4 10 6.2 18.5 3.5 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Mitofilin PF09731.9 KFM62623.1 - 7.9 5.2 32.9 0.64 8.8 27.9 1.6 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DUF842 PF05811.13 KFM62623.1 - 8.4 6.1 21.8 1.4 8.6 11.0 2.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) T3SS_needle_F PF09392.10 KFM62623.1 - 9.6 6.5 14.4 15 5.9 0.3 4.4 2 2 3 5 5 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Tweety PF04906.13 KFM62623.1 - 9.7 4.7 19.2 0.44 9.2 3.2 3.4 3 1 1 4 4 4 0 Tweety HTH_Tnp_Tc3_2 PF01498.18 KFM62625.1 - 8.6e-16 58.0 6.5 1.5e-15 57.2 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM62625.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM62625.1 - 0.0041 16.9 0.3 0.12 12.2 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62625.1 - 0.01 15.9 0.3 0.066 13.4 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM62625.1 - 0.024 14.6 2.6 0.036 14.1 0.4 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM62625.1 - 0.098 12.8 0.0 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Ribosomal_L15e PF00827.17 KFM62626.1 - 3e-88 294.6 6.4 3.3e-88 294.4 6.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF2117 PF09890.9 KFM62626.1 - 0.2 11.1 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) RP1-2 PF12042.8 KFM62627.1 - 8.6e-132 435.7 262.0 4.2e-22 78.8 30.0 10.3 10 1 1 11 11 11 7 Tubuliform egg casing silk strands structural domain Spidroin_N PF16763.5 KFM62627.1 - 2.6e-34 117.9 2.8 2.6e-34 117.9 2.8 8.0 8 3 1 9 9 9 1 Major ampullate spidroin 1, spider silk protein 1, N-term CENP-T_C PF15511.6 KFM62627.1 - 3.1e-06 27.2 0.0 10 6.3 0.0 6.7 7 0 0 7 7 7 1 Centromere kinetochore component CENP-T histone fold EntA_Immun PF08951.10 KFM62627.1 - 7e-05 23.1 12.6 5 7.6 0.5 6.8 6 0 0 6 6 6 2 Enterocin A Immunity Orthopox_F14 PF06076.12 KFM62627.1 - 0.00045 20.4 1.9 89 3.5 0.0 6.5 7 0 0 7 7 7 0 Orthopoxvirus F14 protein Spidroin_MaSp PF11260.8 KFM62627.1 - 0.001 19.3 3.0 0.001 19.3 3.0 19.0 15 7 5 21 21 21 1 Major ampullate spidroin 1 and 2 DUF746 PF05344.11 KFM62627.1 - 0.0043 16.8 0.0 42 4.1 0.0 5.5 6 0 0 6 6 6 0 Domain of Unknown Function (DUF746) Amidohydro_2 PF04909.14 KFM62628.1 - 1.9e-62 211.7 0.0 2.1e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase MMR_HSR1 PF01926.23 KFM62629.1 - 3.6e-23 81.8 0.0 5.1e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 KFM62629.1 - 2.9e-16 59.4 8.1 1.2e-15 57.4 8.1 1.9 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 KFM62629.1 - 1.2e-09 37.9 0.0 2.9e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFM62629.1 - 0.12 11.9 0.0 13 5.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.21 KFM62629.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family HTH_Tnp_Tc3_2 PF01498.18 KFM62630.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62630.1 - 7.3e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_1 PF00001.21 KFM62631.1 - 1.5e-09 37.6 0.5 1.5e-09 37.6 0.5 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM62631.1 - 0.00011 21.6 2.0 0.00014 21.4 2.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx RP1-2 PF12042.8 KFM62633.1 - 5.7e-10 39.3 1.0 5.7e-10 39.3 1.0 2.3 2 0 0 2 2 2 1 Tubuliform egg casing silk strands structural domain Spidroin_N PF16763.5 KFM62633.1 - 3.5e-07 30.3 2.1 1.2e-06 28.6 0.0 3.0 3 0 0 3 3 3 1 Major ampullate spidroin 1, spider silk protein 1, N-term Spidroin_MaSp PF11260.8 KFM62633.1 - 0.017 15.4 0.1 0.17 12.2 0.0 2.7 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 Rft-1 PF04506.13 KFM62634.1 - 9.3e-127 423.9 38.3 1.1e-126 423.6 38.3 1.0 1 0 0 1 1 1 1 Rft protein DUF2606 PF10794.9 KFM62634.1 - 0.044 13.6 0.9 0.12 12.1 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) CBFD_NFYB_HMF PF00808.23 KFM62635.1 - 4.8e-05 23.5 0.0 8.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CBFD_NFYB_HMF PF00808.23 KFM62636.1 - 3.7e-17 62.4 0.3 5.1e-17 61.9 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sigma70_ner PF04546.13 KFM62636.1 - 0.096 12.6 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Biopterin_H PF00351.21 KFM62637.1 - 1.1e-65 221.9 0.1 1.2e-65 221.8 0.1 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase DDE_3 PF13358.6 KFM62638.1 - 9.4e-10 38.4 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2_4 PF13894.6 KFM62639.1 - 4.9e-05 23.8 52.6 0.22 12.5 1.0 9.1 9 0 0 9 9 9 7 C2H2-type zinc finger EF-hand_1 PF00036.32 KFM62640.1 - 0.024 14.1 0.2 0.32 10.6 0.1 2.3 2 0 0 2 2 2 0 EF hand Beta-APP PF03494.13 KFM62640.1 - 0.046 13.6 1.1 0.091 12.6 0.3 1.9 2 1 0 2 2 2 0 Beta-amyloid peptide (beta-APP) EF-hand_6 PF13405.6 KFM62640.1 - 0.078 13.0 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KFM62640.1 - 0.13 12.7 0.0 0.47 11.0 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KFM62641.1 - 2.9e-05 23.3 0.4 7.3e-05 22.0 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFM62641.1 - 3e-05 23.8 0.1 5.3e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KFM62641.1 - 5.7e-05 23.5 0.3 0.00011 22.6 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM62641.1 - 0.00011 21.5 0.1 0.00035 19.9 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFM62641.1 - 0.00075 19.2 0.2 0.0017 18.1 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain THAP PF05485.12 KFM62642.1 - 0.0032 18.4 0.2 0.0033 18.3 0.2 1.0 1 0 0 1 1 1 1 THAP domain rve PF00665.26 KFM62646.1 - 2.4e-07 31.0 0.0 3.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain FERM_M PF00373.18 KFM62647.1 - 9.1e-18 64.8 0.0 1.8e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 FERM central domain 2OG-FeII_Oxy_2 PF13532.6 KFM62648.1 - 6.8e-21 75.3 0.0 9.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HTH_Tnp_Tc3_2 PF01498.18 KFM62649.1 - 1.8e-16 60.1 2.2 3.9e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62649.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease COesterase PF00135.28 KFM62650.1 - 1.9e-26 93.0 0.0 2.2e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family HTH_Tnp_Tc3_2 PF01498.18 KFM62651.1 - 1.8e-16 60.1 2.2 4.4e-16 58.9 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62651.1 - 4.8e-13 49.1 0.0 7.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease UBX PF00789.20 KFM62653.1 - 0.0004 20.5 0.6 0.0024 18.0 0.0 2.3 2 1 0 2 2 2 1 UBX domain DUF572 PF04502.13 KFM62653.1 - 0.015 14.9 15.5 0.016 14.8 15.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ebp2 PF05890.12 KFM62653.1 - 0.053 13.1 20.7 0.067 12.7 20.7 1.1 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 DUF2939 PF11159.8 KFM62653.1 - 0.18 12.2 0.5 0.36 11.3 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) AAA_11 PF13086.6 KFM62653.1 - 0.73 9.6 14.7 0.93 9.2 14.7 1.1 1 0 0 1 1 1 0 AAA domain MAJIN PF15077.6 KFM62653.1 - 1.4 8.6 9.9 1.7 8.4 9.9 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein MCM3AP_GANP PF16769.5 KFM62653.1 - 7.9 4.6 11.6 8.7 4.5 11.6 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP Ank PF00023.30 KFM62655.1 - 1.1e-28 98.4 2.4 2.4e-07 30.9 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_2 PF12796.7 KFM62655.1 - 9.6e-27 93.4 3.7 1.5e-13 51.1 0.3 3.9 3 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM62655.1 - 5.3e-26 90.6 2.0 1.4e-07 31.9 0.0 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM62655.1 - 2.2e-21 75.6 3.5 6.8e-05 23.1 0.0 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM62655.1 - 2.7e-16 58.0 3.6 0.00039 20.7 0.0 7.9 8 0 0 8 8 8 3 Ankyrin repeat IGFBP PF00219.18 KFM62656.1 - 0.0056 17.3 28.1 0.015 16.0 28.1 1.8 1 1 0 1 1 1 1 Insulin-like growth factor binding protein Mito_carr PF00153.27 KFM62657.1 - 2.2e-56 187.7 3.1 1.6e-18 66.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM62657.1 - 0.022 14.0 0.6 0.079 12.1 0.1 2.1 2 1 1 3 3 3 0 Gammaproteobacterial serine protease LURAP PF14854.6 KFM62658.1 - 2.3e-08 34.0 0.0 3.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Leucine rich adaptor protein DUF4530 PF15039.6 KFM62658.1 - 0.025 14.7 1.5 0.048 13.8 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) DUF2046 PF09755.9 KFM62658.1 - 0.035 13.3 2.2 1.5 7.9 0.7 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DDE_3 PF13358.6 KFM62659.1 - 5.1e-08 32.8 0.0 6.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PRANC PF09372.10 KFM62659.1 - 0.096 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 PRANC domain Importin_rep PF18773.1 KFM62659.1 - 0.15 11.8 0.5 0.33 10.7 0.4 1.7 2 0 0 2 2 2 0 Importin 13 repeat Ribosomal_S11 PF00411.19 KFM62660.1 - 2.9e-06 27.7 0.1 3.7e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S11 PF00411.19 KFM62661.1 - 4.2e-21 75.4 0.5 5e-21 75.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KFM62661.1 - 0.022 15.0 0.0 0.023 14.9 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PH PF00169.29 KFM62662.1 - 2.4e-12 47.3 0.1 1.1e-11 45.2 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFM62662.1 - 0.06 13.8 0.1 0.92 10.0 0.1 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Barttin PF15462.6 KFM62662.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Peptidase_M41 PF01434.18 KFM62663.1 - 1.1e-67 227.6 2.6 2e-67 226.7 2.6 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFM62663.1 - 5.3e-43 146.6 0.0 2.3e-42 144.6 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM62663.1 - 9.5e-11 41.3 0.3 9.5e-11 41.3 0.3 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KFM62663.1 - 2.5e-07 30.8 0.0 1.3e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFM62663.1 - 1.4e-05 24.8 0.0 5e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM62663.1 - 5.2e-05 23.7 2.7 0.0058 17.0 0.2 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFM62663.1 - 7.5e-05 23.0 0.3 0.031 14.5 0.0 3.3 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KFM62663.1 - 0.0014 18.0 0.5 0.038 13.4 0.2 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KFM62663.1 - 0.0022 17.2 0.0 0.0078 15.4 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 KFM62663.1 - 0.0039 17.4 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFM62663.1 - 0.0067 16.2 0.0 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 KFM62663.1 - 0.0098 15.6 3.5 1.2 8.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KFM62663.1 - 0.011 15.5 0.1 0.93 9.2 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.6 KFM62663.1 - 0.027 14.7 0.1 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFM62663.1 - 0.052 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KFM62663.1 - 0.054 13.0 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KFM62663.1 - 0.056 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KFM62663.1 - 0.061 13.4 0.0 0.7 10.0 0.0 2.8 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) Death_2 PF14786.6 KFM62663.1 - 0.12 12.3 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 1 0 Tube Death domain AAA_18 PF13238.6 KFM62663.1 - 0.13 12.9 0.0 0.42 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 KFM62663.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KFM62663.1 - 0.37 11.1 1.5 6.7 7.0 0.4 2.9 3 0 0 3 3 3 0 AAA domain DUF4817 PF16087.5 KFM62664.1 - 2.4e-05 24.0 0.0 6.9e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 KFM62664.1 - 0.001 19.7 0.3 0.0039 17.8 0.0 2.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM62664.1 - 0.002 17.9 0.1 0.56 10.1 0.1 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 KFM62664.1 - 0.041 14.0 0.0 5.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM62667.1 - 4.2e-16 59.0 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62667.1 - 1.5e-11 44.3 0.0 2.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62667.1 - 2e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62667.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62667.1 - 1.8 9.2 15.6 0.12 13.0 1.9 3.3 2 1 1 3 3 3 0 Homeodomain-like domain IMD PF08397.11 KFM62669.1 - 6.8e-11 42.0 0.5 1.3e-10 41.0 0.7 1.4 2 0 0 2 2 2 1 IRSp53/MIM homology domain SH3_1 PF00018.28 KFM62669.1 - 2.6e-06 26.9 0.0 6.7e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFM62669.1 - 6.7e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM62669.1 - 8.1e-05 22.2 0.0 0.00019 21.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Arteri_nsp7a PF16749.5 KFM62669.1 - 0.079 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha Ribosomal_L22e PF01776.17 KFM62669.1 - 0.14 12.6 0.2 0.23 11.8 0.2 1.3 1 0 0 1 1 1 0 Ribosomal L22e protein family ER PF01133.17 KFM62669.1 - 0.14 12.2 0.0 0.6 10.2 0.0 2.0 2 0 0 2 2 2 0 Enhancer of rudimentary CRAL_TRIO PF00650.20 KFM62671.1 - 1.5e-28 99.5 0.1 2.2e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM62671.1 - 1.1e-06 29.2 0.1 4.7e-06 27.1 0.0 1.9 1 1 1 2 2 2 1 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.6 KFM62671.1 - 0.00055 20.1 0.1 0.00083 19.5 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain C1q PF00386.21 KFM62671.1 - 0.046 13.9 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 C1q domain TFIIS_M PF07500.14 KFM62672.1 - 1.2e-30 106.3 2.5 1.2e-30 106.3 2.5 4.4 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KFM62672.1 - 7e-11 41.8 10.9 7e-11 41.8 10.9 2.9 2 0 0 2 2 2 1 PHD-finger BRK PF07533.16 KFM62672.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 BRK domain PHD_4 PF16866.5 KFM62672.1 - 0.0091 16.1 8.3 0.0091 16.1 8.3 3.8 3 0 0 3 3 3 1 PHD-finger NdhM PF10664.9 KFM62672.1 - 0.037 14.3 0.3 0.17 12.1 0.1 2.3 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M zf-C6H2 PF15801.5 KFM62672.1 - 1 9.7 8.2 0.77 10.1 2.6 3.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Tudor_2 PF18104.1 KFM62673.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain TGF_beta PF00019.20 KFM62674.1 - 1.7e-25 90.0 0.8 3e-25 89.2 0.8 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFM62674.1 - 0.027 14.2 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 TGF-beta propeptide Calreticulin PF00262.18 KFM62675.1 - 7.9e-80 268.5 13.1 7.2e-58 196.2 4.5 2.3 1 1 1 2 2 2 2 Calreticulin family MDM10 PF12519.8 KFM62675.1 - 0.17 10.7 1.3 0.26 10.1 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CDC45 PF02724.14 KFM62675.1 - 7.5 4.7 14.0 11 4.1 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Serpin PF00079.20 KFM62676.1 - 5.2e-101 338.6 0.2 6.3e-101 338.3 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFM62677.1 - 2.5e-98 329.8 0.2 2.9e-98 329.6 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFM62678.1 - 3.2e-77 260.3 8.3 3.6e-77 260.2 8.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Aldo_ket_red PF00248.21 KFM62679.1 - 3.6e-41 141.3 0.0 2.2e-37 128.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family OTCace_N PF02729.21 KFM62679.1 - 0.21 11.6 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain NUDIX PF00293.28 KFM62681.1 - 1.8e-19 70.1 0.0 2.5e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L37 PF08561.10 KFM62682.1 - 1.6e-07 31.9 3.1 4.3e-07 30.5 3.1 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Kazal_2 PF07648.15 KFM62684.1 - 2.1e-10 40.5 2.4 2.1e-10 40.5 2.4 2.3 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM62684.1 - 5.3e-05 23.1 5.8 0.00014 21.8 5.8 1.9 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Laminin_EGF PF00053.24 KFM62684.1 - 0.00029 20.9 4.7 0.00029 20.9 4.7 3.2 1 1 2 3 3 3 1 Laminin EGF domain DDE_3 PF13358.6 KFM62686.1 - 1e-12 48.0 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Tfb2_C PF18307.1 KFM62686.1 - 0.66 10.4 2.5 24 5.4 0.0 2.8 3 1 0 3 3 3 0 Transcription factor Tfb2 (p52) C-terminal domain DUF1759 PF03564.15 KFM62687.1 - 3.9e-11 43.1 0.5 1.1e-10 41.7 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM62687.1 - 4.6e-05 23.3 0.5 0.00013 21.7 0.1 2.0 2 0 0 2 2 2 1 Putative peptidase (DUF1758) CoiA PF06054.11 KFM62687.1 - 0.039 13.1 1.0 0.084 12.0 0.5 1.8 2 0 0 2 2 2 0 Competence protein CoiA-like family DDE_3 PF13358.6 KFM62688.1 - 4.4e-16 58.9 0.1 5.2e-15 55.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62688.1 - 1.8e-10 40.9 1.0 3.7e-10 39.9 1.0 1.6 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM62689.1 - 2.1e-16 59.9 2.2 4.7e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62689.1 - 5.3e-13 49.0 0.0 8.9e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Prokineticin PF06607.11 KFM62690.1 - 0.00015 22.0 2.0 0.00019 21.7 2.0 1.3 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM62690.1 - 0.0003 21.3 7.7 0.00044 20.8 7.7 1.2 1 0 0 1 1 1 1 MIT-like atracotoxin family Colipase_C PF02740.14 KFM62690.1 - 0.042 14.0 0.1 0.042 14.0 0.1 1.7 2 0 0 2 2 2 0 Colipase, C-terminal domain DX PF01666.17 KFM62690.1 - 1 9.9 6.9 1.2 9.6 4.1 2.3 1 1 1 2 2 2 0 DX module EB PF01683.18 KFM62690.1 - 1.6 9.1 10.6 9.1 6.7 0.8 3.2 2 1 0 2 2 2 0 EB module HTH_Tnp_Tc3_2 PF01498.18 KFM62692.1 - 8.1e-18 64.5 1.7 1.5e-17 63.6 1.7 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM62692.1 - 5.2e-06 27.0 5.5 8.3e-05 23.1 1.3 2.4 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM62692.1 - 0.00042 20.1 0.9 0.029 14.3 0.0 2.6 2 1 0 2 2 2 1 MarR family HTH_3 PF01381.22 KFM62692.1 - 0.00049 20.1 0.7 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix PAX PF00292.18 KFM62692.1 - 0.0023 17.9 0.0 0.0047 16.9 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_Crp_2 PF13545.6 KFM62692.1 - 0.011 15.7 0.4 0.044 13.8 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM62692.1 - 0.051 13.2 0.6 2.5 7.7 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 KFM62692.1 - 0.073 12.6 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 KFM62692.1 - 0.12 12.2 2.2 1.3 9.0 0.1 2.9 3 0 0 3 3 3 0 Homeodomain-like domain FUR PF01475.19 KFM62692.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_28 PF13518.6 KFM62692.1 - 0.36 11.0 2.7 1.5 9.0 0.3 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain MLVIN_C PF18697.1 KFM62693.1 - 0.005 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_3 PF13358.6 KFM62693.1 - 0.01 15.6 0.1 0.047 13.4 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62694.1 - 4.8e-16 58.8 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62694.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62694.1 - 2e-07 30.7 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62694.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62694.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62695.1 - 5.8e-16 58.5 6.5 9.1e-16 57.9 6.5 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM62695.1 - 0.00046 20.7 1.5 0.00046 20.7 1.5 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM62695.1 - 0.0086 15.8 2.1 0.081 12.7 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62695.1 - 0.013 15.6 0.1 0.044 13.9 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM62695.1 - 0.016 15.2 2.4 0.024 14.7 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM62695.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase EF-hand_4 PF12763.7 KFM62696.1 - 2.9e-16 59.3 0.1 6.6e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFM62696.1 - 1.1e-05 24.6 0.0 2.5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFM62696.1 - 0.0035 17.8 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFM62696.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 KFM62696.1 - 0.065 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 EF hand CAF1C_H4-bd PF12265.8 KFM62697.1 - 2.2e-28 98.3 1.5 2.4e-27 95.0 0.3 2.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFM62697.1 - 6.4e-28 96.4 14.0 2e-07 31.6 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM62697.1 - 4.8e-05 23.6 1.8 0.014 15.7 0.1 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM62697.1 - 0.00012 22.0 0.8 0.027 14.4 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Thiolase_N PF00108.23 KFM62698.1 - 1.4e-89 299.9 0.4 2.1e-89 299.3 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFM62698.1 - 4.1e-37 126.6 0.2 9.2e-37 125.4 0.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFM62698.1 - 0.00018 21.2 1.5 0.00018 21.2 1.5 2.3 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain FERM_M PF00373.18 KFM62699.1 - 1.1e-28 100.1 0.1 2.2e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 KFM62699.1 - 3.4e-27 94.7 0.0 8.4e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFM62699.1 - 1.1e-14 54.1 0.6 5.3e-14 51.9 0.1 2.2 2 0 0 2 2 2 1 FERM N-terminal domain ACBP PF00887.19 KFM62699.1 - 8.8e-06 25.8 0.6 4.8e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 Acyl CoA binding protein ERM PF00769.19 KFM62700.1 - 4.8e-63 213.2 53.0 5.4e-63 213.1 53.0 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family YtxH PF12732.7 KFM62701.1 - 6.3e-33 113.1 119.8 0.0002 21.8 6.1 14.6 4 4 8 13 13 13 11 YtxH-like protein Apolipoprotein PF01442.18 KFM62701.1 - 8.6e-33 113.8 75.4 1.6e-08 34.7 14.2 7.0 1 1 6 8 8 8 8 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KFM62701.1 - 9.9e-19 67.7 67.5 0.0065 17.0 2.6 10.7 5 3 3 9 9 9 7 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 KFM62701.1 - 1.2e-14 54.7 68.5 0.013 15.6 1.8 8.9 2 2 5 8 8 8 8 Apolipophorin-III precursor (apoLp-III) Gp-FAR-1 PF05823.12 KFM62701.1 - 3.3e-14 53.5 103.3 0.0082 16.5 5.9 9.2 1 1 8 9 9 9 7 Nematode fatty acid retinoid binding protein (Gp-FAR-1) phiKZ_IP PF12699.7 KFM62701.1 - 8.1e-11 41.7 92.1 0.025 13.8 4.7 13.0 2 1 10 13 13 13 7 phiKZ-like phage internal head proteins Apo-CIII PF05778.12 KFM62701.1 - 1.2e-06 28.0 14.9 9.3 6.0 0.0 8.7 8 1 0 8 8 8 0 Apolipoprotein CIII (Apo-CIII) Muted PF14942.6 KFM62701.1 - 3.8e-06 27.3 109.4 0.11 12.8 8.0 8.5 1 1 7 8 8 8 4 Organelle biogenesis, Muted-like protein Baculo_PEP_C PF04513.12 KFM62701.1 - 6e-06 26.3 14.0 13 5.8 0.0 9.4 4 4 7 12 12 12 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4455 PF14643.6 KFM62701.1 - 6.1e-06 25.2 92.5 0.00031 19.5 24.3 5.3 1 1 2 4 4 4 2 Domain of unknown function (DUF4455) Prominin PF05478.11 KFM62701.1 - 7.9e-06 24.1 52.7 0.0053 14.8 6.8 5.1 1 1 4 5 5 5 5 Prominin DUF1664 PF07889.12 KFM62701.1 - 1.1e-05 25.5 72.1 0.024 14.7 2.6 8.3 6 2 0 8 8 8 4 Protein of unknown function (DUF1664) DUF4413 PF14372.6 KFM62701.1 - 1.4e-05 25.3 65.3 0.46 10.9 0.5 11.2 4 4 5 10 10 10 4 Domain of unknown function (DUF4413) Z1 PF10593.9 KFM62701.1 - 1.9e-05 24.3 60.8 0.063 12.8 1.8 7.9 1 1 6 7 7 7 4 Z1 domain BMFP PF04380.13 KFM62701.1 - 2.8e-05 24.5 45.7 4.6 7.8 1.6 11.8 7 5 2 10 10 10 0 Membrane fusogenic activity PhageMin_Tail PF10145.9 KFM62701.1 - 9.3e-05 22.4 6.2 6.7 6.5 0.2 6.9 1 1 3 5 5 5 0 Phage-related minor tail protein DLP_helical PF18709.1 KFM62701.1 - 0.00012 21.5 75.3 0.011 14.9 7.7 7.5 1 1 5 7 7 7 5 Dynamin-like helical domain ApoC-I PF04691.12 KFM62701.1 - 0.00023 21.0 108.3 0.1 12.5 2.3 17.5 11 4 3 16 16 15 5 Apolipoprotein C-I (ApoC-1) OmpH PF03938.14 KFM62701.1 - 0.00026 21.4 117.0 0.05 13.9 14.7 8.9 1 1 7 8 8 8 3 Outer membrane protein (OmpH-like) DUF3584 PF12128.8 KFM62701.1 - 0.00037 18.2 99.2 0.013 13.1 12.8 4.7 1 1 4 5 5 5 4 Protein of unknown function (DUF3584) 7TMR-HDED PF07697.11 KFM62701.1 - 0.00061 20.0 69.7 0.66 10.1 11.0 6.3 1 1 3 4 4 4 1 7TM-HD extracellular CK2S PF15011.6 KFM62701.1 - 0.0023 17.8 60.5 0.073 13.0 0.6 10.3 2 2 5 8 8 8 2 Casein Kinase 2 substrate Exonuc_VII_L PF02601.15 KFM62701.1 - 0.0029 17.2 59.8 0.17 11.4 3.3 5.5 1 1 1 3 3 1 1 Exonuclease VII, large subunit AAA_15 PF13175.6 KFM62701.1 - 0.0034 17.1 27.8 0.0034 17.1 27.8 5.4 1 1 2 4 4 3 2 AAA ATPase domain Lectin_N PF03954.14 KFM62701.1 - 0.0057 16.4 38.4 0.14 11.9 0.2 7.2 7 1 0 7 7 7 3 Hepatic lectin, N-terminal domain CCDC32 PF14989.6 KFM62701.1 - 0.0064 16.5 97.8 0.2 11.6 3.6 8.6 2 1 7 9 9 9 4 Coiled-coil domain containing 32 ABATE PF07336.11 KFM62701.1 - 0.007 17.0 0.5 1.2e+02 3.3 0.0 5.5 6 0 0 6 6 6 0 Putative stress-induced transcription regulator DUF1654 PF07867.11 KFM62701.1 - 0.0077 15.9 29.2 0.03 14.1 0.3 8.7 9 0 0 9 9 8 1 Protein of unknown function (DUF1654) GOLGA2L5 PF15070.6 KFM62701.1 - 0.012 14.4 78.4 0.1 11.2 48.2 4.9 1 1 3 4 4 4 0 Putative golgin subfamily A member 2-like protein 5 DUF4734 PF15881.5 KFM62701.1 - 0.022 14.9 6.1 1.1e+02 3.1 0.1 6.8 6 1 0 6 6 6 0 Domain of unknown function (DUF4734) DUF3583 PF12126.8 KFM62701.1 - 0.024 14.1 0.8 0.024 14.1 0.8 6.5 6 1 0 7 7 7 0 Protein of unknown function (DUF3583) DUF3365 PF11845.8 KFM62701.1 - 0.037 14.4 5.2 2.9 8.2 0.1 5.1 3 3 0 3 3 3 0 Protein of unknown function (DUF3365) HHH_2 PF12826.7 KFM62701.1 - 0.039 14.0 2.7 0.61 10.2 0.1 4.1 4 0 0 4 4 2 0 Helix-hairpin-helix motif DUF5601 PF18151.1 KFM62701.1 - 0.047 14.0 8.3 22 5.4 0.2 6.4 6 2 0 6 6 4 0 Domain of unknown function (DUF5601) DUF948 PF06103.11 KFM62701.1 - 0.064 13.5 30.3 4.1 7.7 0.3 9.0 7 4 1 9 9 9 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.11 KFM62701.1 - 0.087 12.6 63.3 0.043 13.7 3.3 8.6 5 2 3 8 8 8 0 Bacillus haemolytic enterotoxin (HBL) AAA_33 PF13671.6 KFM62701.1 - 0.12 12.5 0.2 0.74 10.0 0.2 2.4 1 0 0 1 1 1 0 AAA domain T3SS_basalb_I PF17001.5 KFM62701.1 - 0.14 12.8 10.1 46 4.7 0.0 6.8 6 1 1 7 7 7 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF445 PF04286.12 KFM62701.1 - 0.17 11.7 98.1 0.086 12.6 13.6 4.6 1 1 3 4 4 4 0 Protein of unknown function (DUF445) Baculo_p24 PF05073.12 KFM62701.1 - 0.19 11.5 37.5 1.4 8.7 1.4 7.1 1 1 5 7 7 7 0 Baculovirus P24 capsid protein PEP-utilisers_N PF05524.13 KFM62701.1 - 0.22 11.7 43.8 1.8 8.8 0.9 7.8 2 2 6 8 8 8 0 PEP-utilising enzyme, N-terminal Phasin PF05597.11 KFM62701.1 - 0.27 11.2 79.1 0.5 10.4 8.2 10.6 2 2 8 11 11 11 0 Poly(hydroxyalcanoate) granule associated protein (phasin) OS-D PF03392.13 KFM62701.1 - 0.29 11.2 54.8 2.2 8.5 0.7 9.2 7 1 0 7 7 7 0 Insect pheromone-binding family, A10/OS-D DUF885 PF05960.11 KFM62701.1 - 0.49 10.0 53.7 1.5 8.4 1.3 6.1 1 1 2 3 3 2 0 Bacterial protein of unknown function (DUF885) DUF1924 PF09086.11 KFM62701.1 - 0.85 10.0 16.0 34 4.9 0.1 6.2 6 0 0 6 6 5 0 Domain of unknown function (DUF1924) Carbpep_Y_N PF05388.11 KFM62701.1 - 1.1 9.8 67.3 0.96 10.0 1.3 10.6 2 2 2 9 9 8 0 Carboxypeptidase Y pro-peptide HisKA_3 PF07730.13 KFM62701.1 - 1.1 9.8 31.0 13 6.4 0.2 11.7 8 6 3 11 11 10 0 Histidine kinase Nup54 PF13874.6 KFM62701.1 - 2.1 8.5 49.4 0.38 10.8 0.7 7.6 2 1 6 8 8 7 0 Nucleoporin complex subunit 54 DUF3437 PF11919.8 KFM62701.1 - 2.7 8.0 37.8 11 6.0 0.7 8.5 8 0 0 8 8 8 0 Domain of unknown function (DUF3437) AAA_32 PF13654.6 KFM62701.1 - 3.1 6.5 101.0 0.68 8.6 26.5 6.3 1 1 4 6 6 6 0 AAA domain Herpes_UL6 PF01763.16 KFM62701.1 - 3.8 5.9 60.0 0.044 12.3 2.8 6.7 1 1 6 7 7 7 0 Herpesvirus UL6 like DUF3268 PF11672.8 KFM62701.1 - 5.3 7.4 14.2 38 4.6 0.1 5.8 5 0 0 5 5 5 0 zinc-finger-containing domain APOC4 PF15119.6 KFM62701.1 - 5.3 7.4 26.7 14 6.0 0.1 8.4 8 2 0 8 8 7 0 Apolipoprotein C4 Atypical_Card PF18461.1 KFM62701.1 - 6.3 7.1 26.0 43 4.4 0.1 8.1 7 2 1 8 8 8 0 Atypical caspase recruitment domain ApoO PF09769.9 KFM62701.1 - 6.4 6.8 14.6 27 4.7 0.3 6.7 5 2 1 6 6 6 0 Apolipoprotein O DSPc PF00782.20 KFM62701.1 - 8 6.3 23.4 10 6.0 0.2 7.4 7 1 0 7 7 7 0 Dual specificity phosphatase, catalytic domain gag-asp_proteas PF13975.6 KFM62702.1 - 6.6e-11 42.6 0.0 1.6e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM62702.1 - 4.6e-09 36.8 0.0 9.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 KFM62702.1 - 5e-06 26.7 0.3 1.2e-05 25.5 0.3 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 KFM62702.1 - 5.1e-05 23.1 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KFM62702.1 - 5.6e-05 23.4 0.0 0.00017 21.9 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KFM62702.1 - 0.0003 20.6 0.0 0.00069 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 KFM62702.1 - 0.0012 18.8 1.4 0.0012 18.8 1.4 2.0 2 0 0 2 2 2 1 Zinc knuckle NKWYS PF10364.9 KFM62702.1 - 0.019 15.1 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Asp PF00026.23 KFM62702.1 - 0.14 11.6 0.1 5.4 6.3 0.0 2.8 2 1 0 3 3 3 0 Eukaryotic aspartyl protease DUF4342 PF14242.6 KFM62704.1 - 0.012 15.6 1.3 0.012 15.6 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) YtxH PF12732.7 KFM62704.1 - 0.11 13.0 0.9 0.12 12.9 0.9 1.1 1 0 0 1 1 1 0 YtxH-like protein SF-assemblin PF06705.11 KFM62705.1 - 0.0055 16.1 0.3 0.0059 16.0 0.3 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin YtxH PF12732.7 KFM62705.1 - 0.0068 16.9 1.2 0.02 15.4 1.2 1.7 1 1 0 1 1 1 1 YtxH-like protein PAH PF02671.21 KFM62705.1 - 0.021 15.0 0.3 0.031 14.4 0.3 1.4 1 0 0 1 1 1 0 Paired amphipathic helix repeat ZYG-11_interact PF05884.12 KFM62705.1 - 0.098 12.1 0.1 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 CN_hydrolase PF00795.22 KFM62706.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase VWA_N PF08399.11 KFM62706.1 - 0.088 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 VWA N-terminal YtxH PF12732.7 KFM62707.1 - 2.2e-32 111.4 160.3 6.3e-06 26.6 7.3 16.7 5 5 7 13 13 12 9 YtxH-like protein Apolipoprotein PF01442.18 KFM62707.1 - 9.8e-31 107.1 96.1 1.5e-08 34.7 13.6 7.2 2 1 6 8 8 8 8 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KFM62707.1 - 3.5e-26 91.6 90.2 0.0012 19.4 2.3 13.0 5 2 7 13 13 13 9 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 KFM62707.1 - 3.1e-14 53.3 102.1 0.01 15.9 3.6 10.1 4 3 2 8 8 8 7 Apolipophorin-III precursor (apoLp-III) Gp-FAR-1 PF05823.12 KFM62707.1 - 5.8e-11 42.9 144.9 0.004 17.5 9.6 9.9 1 1 8 10 10 10 6 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Apo-CIII PF05778.12 KFM62707.1 - 1.5e-09 37.4 26.9 0.045 13.4 0.2 9.9 10 3 0 10 10 9 3 Apolipoprotein CIII (Apo-CIII) phiKZ_IP PF12699.7 KFM62707.1 - 4.2e-08 32.7 118.4 0.048 12.8 5.4 14.5 4 4 7 13 13 13 9 phiKZ-like phage internal head proteins QIL1 PF15884.5 KFM62707.1 - 6.2e-08 33.1 53.7 0.84 10.3 0.9 12.2 9 4 3 12 12 11 2 MICOS complex subunit MIC13, QIL1 DUF4413 PF14372.6 KFM62707.1 - 3.3e-07 30.6 78.8 0.047 14.0 0.2 12.8 6 5 2 10 10 10 6 Domain of unknown function (DUF4413) Prominin PF05478.11 KFM62707.1 - 6.2e-06 24.5 75.5 0.0028 15.7 9.8 5.9 1 1 5 6 6 6 5 Prominin Baculo_PEP_C PF04513.12 KFM62707.1 - 1.5e-05 25.1 22.4 4 7.5 0.0 10.4 6 3 2 10 10 10 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KFM62707.1 - 3e-05 24.1 95.5 0.21 11.6 2.9 10.5 7 2 4 11 11 11 6 Protein of unknown function (DUF1664) CbiN PF02553.15 KFM62707.1 - 0.00021 21.2 2.5 1.3e+02 2.7 0.0 6.9 6 0 0 6 6 6 0 Cobalt transport protein component CbiN DLP_helical PF18709.1 KFM62707.1 - 0.00048 19.4 98.1 0.074 12.2 7.0 8.8 1 1 8 9 9 9 6 Dynamin-like helical domain AAA_15 PF13175.6 KFM62707.1 - 0.0026 17.5 170.5 0.0062 16.3 26.6 6.4 1 1 4 5 5 4 4 AAA ATPase domain 7TMR-HDED PF07697.11 KFM62707.1 - 0.0028 17.8 85.9 2.7 8.1 20.1 7.1 1 1 3 4 4 2 1 7TM-HD extracellular Mating_N PF12731.7 KFM62707.1 - 0.013 15.5 5.5 15 5.8 0.1 5.6 5 0 0 5 5 5 0 Mating-type protein beta 1 T2SSF PF00482.23 KFM62707.1 - 0.017 15.1 23.1 0.49 10.4 0.2 8.5 7 1 2 9 9 9 0 Type II secretion system (T2SS), protein F VWA PF00092.28 KFM62707.1 - 0.019 15.3 0.4 0.019 15.3 0.4 5.4 4 2 4 8 8 7 0 von Willebrand factor type A domain PhageMin_Tail PF10145.9 KFM62707.1 - 0.021 14.7 33.4 1.9e+02 1.8 1.0 9.5 2 2 0 2 2 1 0 Phage-related minor tail protein Baculo_p24 PF05073.12 KFM62707.1 - 0.026 14.3 65.1 1.3 8.8 0.8 9.5 2 2 10 12 12 12 0 Baculovirus P24 capsid protein DUF2935 PF11155.8 KFM62707.1 - 0.064 13.6 28.7 8 6.8 0.0 8.5 2 1 2 4 4 3 0 Domain of unknown function (DUF2935) OmpH PF03938.14 KFM62707.1 - 0.12 12.7 156.0 0.15 12.4 14.3 10.1 1 1 5 8 8 6 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 KFM62707.1 - 0.15 11.6 83.5 3.9 6.9 1.8 7.1 1 1 2 3 3 1 0 Exonuclease VII, large subunit Bromo_TP PF07524.13 KFM62707.1 - 0.18 11.8 6.2 1.4e+02 2.6 0.0 7.5 10 0 0 10 10 7 0 Bromodomain associated DUF1654 PF07867.11 KFM62707.1 - 0.21 11.3 22.5 28 4.6 0.0 8.3 8 0 0 8 8 8 0 Protein of unknown function (DUF1654) DUF3268 PF11672.8 KFM62707.1 - 0.34 11.2 16.8 0.76 10.1 0.1 6.3 6 0 0 6 6 6 0 zinc-finger-containing domain Lant_dehydr_N PF04738.13 KFM62707.1 - 0.45 8.5 27.7 2.4 6.2 0.2 7.1 1 1 6 8 8 8 0 Lantibiotic dehydratase, N terminus DUF3583 PF12126.8 KFM62707.1 - 1.3 8.5 62.1 0.039 13.4 0.6 7.9 6 1 2 8 8 8 0 Protein of unknown function (DUF3583) DUF4037 PF13228.6 KFM62707.1 - 1.8 9.4 8.7 3.3 8.5 0.1 5.2 5 2 0 5 5 3 0 Domain of unknown function (DUF4037) Stomoxyn PF11585.8 KFM62707.1 - 2.2 8.3 21.3 2.8 8.0 0.1 6.6 7 0 0 7 7 5 0 Insect antimicrobial peptide, stomoxyn DUF2884 PF11101.8 KFM62707.1 - 2.6 7.5 79.2 0.12 11.8 10.1 8.8 1 1 9 10 10 10 0 Protein of unknown function (DUF2884) PAH PF02671.21 KFM62707.1 - 2.7 8.2 13.9 2.5 8.3 0.3 5.9 5 1 0 5 5 4 0 Paired amphipathic helix repeat Phasin PF05597.11 KFM62707.1 - 2.7 8.0 108.3 0.58 10.2 1.4 11.3 4 3 7 11 11 11 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Nup54 PF13874.6 KFM62707.1 - 3.2 7.8 72.9 4.8 7.3 4.4 9.6 1 1 8 9 9 9 0 Nucleoporin complex subunit 54 SseB_C PF14581.6 KFM62707.1 - 3.8 7.6 30.5 0.81 9.8 0.4 8.1 8 2 1 9 9 7 0 SseB protein C-terminal domain DUF3584 PF12128.8 KFM62707.1 - 4.7 4.6 125.9 0.079 10.5 34.7 5.4 1 1 2 4 4 4 0 Protein of unknown function (DUF3584) DUF2203 PF09969.9 KFM62707.1 - 6.1 7.6 91.0 2.9 8.6 3.9 10.2 6 2 2 9 9 9 0 Uncharacterized conserved protein (DUF2203) EF-hand_10 PF14788.6 KFM62707.1 - 6.3 6.8 15.1 2.1 8.2 0.4 4.8 4 0 0 4 4 4 0 EF hand PGM_PMM_II PF02879.16 KFM62707.1 - 9.7 6.9 7.9 13 6.4 0.1 5.1 7 2 0 7 7 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II HTH_Tnp_Tc3_2 PF01498.18 KFM62708.1 - 4.6e-16 58.8 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62708.1 - 1.3e-13 51.0 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62708.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62708.1 - 0.0026 17.5 0.6 0.0076 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62708.1 - 0.028 14.6 0.4 0.091 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM62708.1 - 2.5 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Apolipoprotein PF01442.18 KFM62710.1 - 1.5e-18 67.4 55.3 1.3e-05 25.1 20.2 5.7 1 1 4 5 5 5 5 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KFM62710.1 - 4e-18 65.7 87.2 0.00055 20.4 6.6 12.4 3 3 4 7 7 6 5 YtxH-like protein DUF883 PF05957.13 KFM62710.1 - 6.4e-16 58.7 51.9 0.0027 18.3 2.3 9.7 3 2 11 14 14 14 6 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 KFM62710.1 - 1.6e-10 41.2 51.0 0.14 12.2 2.3 7.5 3 3 2 7 7 7 5 Apolipophorin-III precursor (apoLp-III) DUF2935 PF11155.8 KFM62710.1 - 1.9e-06 28.2 3.5 2.9 8.3 0.9 5.8 3 2 0 4 4 4 1 Domain of unknown function (DUF2935) QIL1 PF15884.5 KFM62710.1 - 3e-05 24.5 21.2 0.55 10.9 1.1 7.7 6 2 1 7 7 7 2 MICOS complex subunit MIC13, QIL1 Gp-FAR-1 PF05823.12 KFM62710.1 - 0.00013 22.4 77.8 0.038 14.3 11.7 7.7 1 1 5 6 6 6 3 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CK2S PF15011.6 KFM62710.1 - 0.0012 18.7 40.3 0.42 10.5 0.1 7.5 7 3 1 8 8 8 2 Casein Kinase 2 substrate phiKZ_IP PF12699.7 KFM62710.1 - 0.0023 17.1 62.9 0.0076 15.4 1.7 8.6 4 4 3 8 8 8 4 phiKZ-like phage internal head proteins Bacillus_HBL PF05791.11 KFM62710.1 - 0.0059 16.5 5.5 0.0059 16.5 5.5 7.3 3 1 4 8 8 7 1 Bacillus haemolytic enterotoxin (HBL) 7TMR-HDED PF07697.11 KFM62710.1 - 0.0072 16.5 51.0 8.4 6.5 14.8 5.5 1 1 1 2 2 1 0 7TM-HD extracellular PAH PF02671.21 KFM62710.1 - 0.0083 16.3 6.3 3 8.0 0.1 5.0 4 0 0 4 4 4 1 Paired amphipathic helix repeat DUF4413 PF14372.6 KFM62710.1 - 0.01 16.2 38.9 1.4 9.3 1.1 8.7 4 3 3 8 8 8 0 Domain of unknown function (DUF4413) Prominin PF05478.11 KFM62710.1 - 0.011 13.7 36.4 0.13 10.2 9.5 4.0 1 1 3 4 4 4 0 Prominin CbiN PF02553.15 KFM62710.1 - 0.012 15.6 0.5 9.8 6.2 0.0 4.0 3 0 0 3 3 3 0 Cobalt transport protein component CbiN DUF1664 PF07889.12 KFM62710.1 - 0.038 14.0 46.6 0.2 11.7 1.5 6.7 5 1 1 7 7 7 0 Protein of unknown function (DUF1664) PGM_PMM_II PF02879.16 KFM62710.1 - 0.072 13.7 3.0 6.5 7.4 0.1 4.7 5 0 0 5 5 5 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ZYG-11_interact PF05884.12 KFM62710.1 - 0.074 12.5 10.5 11 5.3 0.0 5.1 3 2 2 5 5 5 0 Interactor of ZYG-11 Exonuc_VII_L PF02601.15 KFM62710.1 - 0.1 12.2 43.0 12 5.3 7.5 4.5 1 1 2 3 3 2 0 Exonuclease VII, large subunit SseB_C PF14581.6 KFM62710.1 - 0.17 12.0 11.8 0.5 10.5 0.4 5.5 4 2 3 7 7 7 0 SseB protein C-terminal domain DUF3268 PF11672.8 KFM62710.1 - 0.18 12.2 9.6 0.58 10.5 0.1 3.6 4 0 0 4 4 3 0 zinc-finger-containing domain DLP_helical PF18709.1 KFM62710.1 - 0.41 9.8 60.0 0.68 9.1 10.7 5.6 2 2 3 6 6 6 0 Dynamin-like helical domain DUF4404 PF14357.6 KFM62710.1 - 0.61 10.8 40.4 0.24 12.0 1.5 7.8 4 2 3 7 7 7 0 Domain of unknown function (DUF4404) Z1 PF10593.9 KFM62710.1 - 0.65 9.5 38.4 0.099 12.1 0.2 6.0 2 2 4 6 6 6 0 Z1 domain MLD PF11647.8 KFM62710.1 - 0.68 10.3 15.7 32 4.9 0.0 6.2 5 2 2 7 7 6 0 Membrane Localization Domain DUF3437 PF11919.8 KFM62710.1 - 1.2 9.1 14.3 2.3 8.2 1.2 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) Ribonuc_2-5A PF06479.12 KFM62710.1 - 1.5 9.0 32.0 0.58 10.3 4.5 5.9 2 2 3 5 5 5 0 Ribonuclease 2-5A Sirohm_synth_C PF14823.6 KFM62710.1 - 1.7 8.3 17.9 5.9 6.6 0.2 6.2 6 0 0 6 6 6 0 Sirohaem biosynthesis protein C-terminal Phasin PF05597.11 KFM62710.1 - 1.8 8.6 59.7 0.19 11.7 2.2 7.9 4 3 4 8 8 8 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3584 PF12128.8 KFM62710.1 - 1.8 6.0 67.0 0.0024 15.5 21.7 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) AAA_15 PF13175.6 KFM62710.1 - 2.1 8.0 88.9 0.5 10.0 27.6 3.8 1 1 2 3 3 3 0 AAA ATPase domain DUF948 PF06103.11 KFM62710.1 - 2.3 8.5 18.9 5.7 7.3 0.3 7.1 7 1 0 7 7 6 0 Bacterial protein of unknown function (DUF948) DUF4735 PF15882.5 KFM62710.1 - 5.6 6.3 16.2 8.2 5.8 0.2 4.6 3 1 0 4 4 4 0 Domain of unknown function (DUF4735) DUF2203 PF09969.9 KFM62710.1 - 8.6 7.1 50.5 1.6 9.5 2.2 7.0 4 1 3 7 7 7 0 Uncharacterized conserved protein (DUF2203) ApoO PF09769.9 KFM62710.1 - 9.5 6.2 9.6 68 3.4 0.0 5.6 4 3 2 6 6 6 0 Apolipoprotein O Snapin_Pallidin PF14712.6 KFM62710.1 - 9.8 6.7 39.0 3.1 8.3 1.1 6.6 5 0 0 5 5 5 0 Snapin/Pallidin Smg8_Smg9 PF10220.9 KFM62712.1 - 0.00091 17.7 0.7 0.001 17.5 0.7 1.0 1 0 0 1 1 1 1 Smg8_Smg9 DUF3150 PF11348.8 KFM62712.1 - 0.0026 17.0 1.2 0.0041 16.4 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3150) AAA_13 PF13166.6 KFM62712.1 - 0.0071 15.1 6.3 0.008 14.9 6.3 1.1 1 0 0 1 1 1 1 AAA domain CHAD PF05235.14 KFM62712.1 - 0.0094 16.0 4.8 0.021 14.8 4.5 1.7 1 1 1 2 2 2 1 CHAD domain ApoLp-III PF07464.11 KFM62712.1 - 0.0095 16.0 3.0 0.01 16.0 1.1 1.8 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF1825 PF08855.10 KFM62712.1 - 0.014 15.3 5.3 0.021 14.7 4.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) DUF2252 PF10009.9 KFM62712.1 - 0.017 14.2 0.5 0.021 13.9 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Reo_P9 PF06043.11 KFM62712.1 - 0.028 13.8 0.4 0.035 13.5 0.4 1.1 1 0 0 1 1 1 0 Reovirus P9-like family Herpes_UL6 PF01763.16 KFM62712.1 - 0.039 12.5 1.3 0.046 12.2 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like TMP_2 PF06791.13 KFM62712.1 - 0.062 13.0 0.2 0.12 12.0 0.2 1.5 1 1 0 1 1 1 0 Prophage tail length tape measure protein Phasin PF05597.11 KFM62712.1 - 0.07 13.1 9.9 0.076 13.0 5.2 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TMPIT PF07851.13 KFM62712.1 - 0.11 11.7 3.6 0.14 11.4 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein 7TMR-HDED PF07697.11 KFM62712.1 - 0.11 12.6 4.4 0.15 12.1 4.4 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Ubiq_cyt_C_chap PF03981.12 KFM62712.1 - 0.12 12.5 2.0 0.51 10.4 2.0 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C chaperone SpoU_sub_bind PF08032.12 KFM62712.1 - 0.12 12.7 1.4 0.3 11.4 1.4 1.7 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding DUF3492 PF11997.8 KFM62712.1 - 0.12 12.1 0.7 0.15 11.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) YbaB_DNA_bd PF02575.16 KFM62712.1 - 0.13 12.5 8.2 1.4 9.2 0.2 2.8 3 0 0 3 3 3 0 YbaB/EbfC DNA-binding family DNTTIP1_dimer PF18192.1 KFM62712.1 - 0.16 12.3 2.6 1.9 8.9 2.6 2.5 1 1 0 1 1 1 0 DNTTIP1 dimerisation domain Rrn6 PF10214.9 KFM62712.1 - 0.17 10.4 0.9 0.17 10.3 0.9 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF349 PF03993.12 KFM62712.1 - 0.17 12.2 5.4 0.34 11.3 5.4 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Mitofilin PF09731.9 KFM62712.1 - 0.22 10.3 10.4 0.25 10.1 10.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YojJ PF10372.9 KFM62712.1 - 0.29 11.3 9.0 0.77 9.9 1.6 2.7 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus PRKCSH-like PF12999.7 KFM62712.1 - 0.34 10.7 3.5 0.46 10.3 3.2 1.4 1 1 0 1 1 1 0 Glucosidase II beta subunit-like DALR_2 PF09190.11 KFM62712.1 - 0.35 11.4 2.8 0.7 10.4 1.6 2.2 1 1 2 3 3 2 0 DALR domain DctP PF03480.13 KFM62712.1 - 0.43 9.9 4.0 0.61 9.4 4.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DUF1002 PF06207.11 KFM62712.1 - 0.7 9.4 5.3 0.46 10.0 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1002) DUF883 PF05957.13 KFM62712.1 - 0.86 10.2 7.2 1.3 9.7 2.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HK97-gp10_like PF04883.12 KFM62712.1 - 0.98 10.4 5.3 3.4 8.7 0.1 2.5 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component DUF1664 PF07889.12 KFM62712.1 - 1 9.4 6.1 2.2 8.3 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YtxH PF12732.7 KFM62712.1 - 1.2 9.8 7.9 16 6.1 7.9 2.3 1 1 0 1 1 1 0 YtxH-like protein IATP PF04568.12 KFM62712.1 - 2.7 8.5 8.7 1.5 9.3 5.4 2.2 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP RNase_J_C PF17770.1 KFM62712.1 - 4.3 8.4 7.9 51 5.0 2.8 3.1 2 1 1 3 3 2 0 Ribonuclease J C-terminal domain YtxH PF12732.7 KFM62713.1 - 0.00073 20.0 2.1 0.044 14.3 2.1 2.1 1 1 0 1 1 1 1 YtxH-like protein DUF1351 PF07083.11 KFM62713.1 - 0.0085 15.9 3.3 0.01 15.6 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) Apolipoprotein PF01442.18 KFM62713.1 - 0.023 14.6 0.2 0.059 13.2 0.2 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain RyR PF02026.16 KFM62713.1 - 0.057 13.6 0.1 0.092 12.9 0.1 1.4 1 0 0 1 1 1 0 RyR domain DUF892 PF05974.12 KFM62713.1 - 0.06 13.4 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF892) PI31_Prot_N PF11566.8 KFM62713.1 - 0.073 12.9 0.0 0.086 12.6 0.0 1.0 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal DUF883 PF05957.13 KFM62713.1 - 0.086 13.5 0.2 0.2 12.3 0.2 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HTH_Tnp_Tc3_2 PF01498.18 KFM62714.1 - 8.7e-13 48.3 0.4 8.7e-13 48.3 0.4 2.4 2 0 0 2 2 2 1 Transposase HTH_3 PF01381.22 KFM62714.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_32 PF13565.6 KFM62714.1 - 0.068 13.8 0.2 0.068 13.8 0.2 3.6 3 1 0 3 3 3 0 Homeodomain-like domain Retrotrans_gag PF03732.17 KFM62715.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein YtxH PF12732.7 KFM62716.1 - 1.3e-06 28.8 11.7 8.1e-06 26.3 4.5 3.1 1 1 1 2 2 2 1 YtxH-like protein DUF883 PF05957.13 KFM62716.1 - 5.3e-06 27.0 4.4 6.7e-06 26.6 3.1 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) ApoC-I PF04691.12 KFM62716.1 - 1.9e-05 24.5 3.7 0.0021 18.0 0.4 2.7 2 0 0 2 2 2 1 Apolipoprotein C-I (ApoC-1) ApoLp-III PF07464.11 KFM62716.1 - 0.00026 21.1 1.2 0.0004 20.5 1.2 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) RapA_C PF12137.8 KFM62716.1 - 0.00027 20.1 4.3 0.00036 19.7 4.3 1.1 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal Herpes_UL6 PF01763.16 KFM62716.1 - 0.00042 19.0 0.2 0.00044 18.9 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like Apolipoprotein PF01442.18 KFM62716.1 - 0.00044 20.2 5.0 0.00073 19.5 5.0 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PIN_5 PF08745.11 KFM62716.1 - 0.0047 16.4 0.5 0.0065 15.9 0.5 1.3 1 0 0 1 1 1 1 PINc domain ribonuclease Gp-FAR-1 PF05823.12 KFM62716.1 - 0.0069 16.7 7.2 0.013 15.8 6.9 1.6 1 1 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Cas_DxTHG PF09455.10 KFM62716.1 - 0.0077 15.8 2.6 0.0084 15.7 2.6 1.1 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family Atg14 PF10186.9 KFM62716.1 - 0.0084 15.2 1.9 0.009 15.1 1.9 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DHR-2 PF06920.13 KFM62716.1 - 0.018 13.7 0.8 0.018 13.7 0.8 1.9 1 1 1 2 2 2 0 Dock homology region 2 7TMR-HDED PF07697.11 KFM62716.1 - 0.04 14.0 4.9 0.056 13.6 4.9 1.4 1 1 0 1 1 1 0 7TM-HD extracellular HAD_2 PF13419.6 KFM62716.1 - 0.045 13.8 5.6 0.098 12.7 5.6 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Mlp PF03304.13 KFM62716.1 - 0.046 14.0 6.4 0.057 13.6 6.4 1.1 1 0 0 1 1 1 0 Mlp lipoprotein family Phasin PF05597.11 KFM62716.1 - 0.047 13.7 4.6 0.073 13.1 4.3 1.5 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tsc35 PF15079.6 KFM62716.1 - 0.047 13.3 10.9 0.061 12.9 10.9 1.1 1 0 0 1 1 1 0 Testis-specific protein 35 phiKZ_IP PF12699.7 KFM62716.1 - 0.067 12.3 7.0 0.28 10.3 6.9 2.0 1 1 0 1 1 1 0 phiKZ-like phage internal head proteins DUF2309 PF10070.9 KFM62716.1 - 0.075 11.3 0.3 0.082 11.2 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) DUF573 PF04504.14 KFM62716.1 - 0.086 13.5 3.2 0.1 13.3 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF573 SRI PF08236.11 KFM62716.1 - 0.1 12.8 6.1 0.26 11.5 6.0 1.7 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain QIL1 PF15884.5 KFM62716.1 - 0.12 13.0 0.2 10 6.8 0.0 2.5 3 0 0 3 3 2 0 MICOS complex subunit MIC13, QIL1 DUF5063 PF16702.5 KFM62716.1 - 0.14 12.5 4.4 0.17 12.3 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5063) Fib_alpha PF08702.10 KFM62716.1 - 0.15 12.3 3.0 0.15 12.3 1.4 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4342 PF14242.6 KFM62716.1 - 0.15 12.0 4.8 10 6.2 1.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4342) p450 PF00067.22 KFM62716.1 - 0.16 10.7 2.9 0.23 10.2 2.9 1.2 1 0 0 1 1 1 0 Cytochrome P450 Prominin PF05478.11 KFM62716.1 - 0.17 9.8 0.4 0.18 9.7 0.4 1.1 1 0 0 1 1 1 0 Prominin SbcD_C PF12320.8 KFM62716.1 - 0.18 12.1 5.1 0.58 10.5 4.8 2.2 1 1 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain DUF4230 PF14014.6 KFM62716.1 - 0.18 12.0 4.1 0.34 11.2 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) ATP-synt_B PF00430.18 KFM62716.1 - 0.22 11.6 4.9 0.42 10.7 4.9 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) PIN_12 PF16289.5 KFM62716.1 - 0.23 11.9 6.2 0.36 11.3 6.2 1.4 1 0 0 1 1 1 0 PIN domain TMPIT PF07851.13 KFM62716.1 - 0.24 10.6 3.2 0.28 10.4 3.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein RNA_GG_bind PF10258.9 KFM62716.1 - 0.25 11.4 4.5 0.77 9.9 0.4 2.5 2 1 0 2 2 2 0 PHAX RNA-binding domain TMEM192 PF14802.6 KFM62716.1 - 0.25 10.4 2.1 0.23 10.6 0.5 1.6 2 0 0 2 2 2 0 TMEM192 family Rrn6 PF10214.9 KFM62716.1 - 0.26 9.7 1.3 0.28 9.6 1.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BEX PF04538.12 KFM62716.1 - 0.27 11.9 4.1 0.29 11.7 3.4 1.5 1 1 0 1 1 1 0 Brain expressed X-linked like family RBD-FIP PF09457.10 KFM62716.1 - 0.28 11.1 0.3 0.28 11.1 0.3 3.5 4 0 0 4 4 4 0 FIP domain LPD5 PF18799.1 KFM62716.1 - 0.37 11.2 5.1 0.47 10.9 1.3 2.1 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 5 DUF1664 PF07889.12 KFM62716.1 - 0.38 10.8 3.2 0.62 10.1 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MnmE_helical PF12631.7 KFM62716.1 - 0.43 10.7 5.2 0.58 10.3 5.2 1.2 1 0 0 1 1 1 0 MnmE helical domain Stathmin PF00836.19 KFM62716.1 - 0.44 10.5 9.4 0.78 9.7 9.1 1.7 1 1 0 1 1 1 0 Stathmin family DUF1451 PF07295.11 KFM62716.1 - 0.47 10.5 4.7 0.47 10.5 3.9 1.4 1 1 0 1 1 1 0 Zinc-ribbon containing domain Syntaxin_2 PF14523.6 KFM62716.1 - 0.5 10.8 4.8 0.94 9.9 4.7 1.6 1 1 0 1 1 1 0 Syntaxin-like protein OmpH PF03938.14 KFM62716.1 - 0.53 10.6 10.0 2.6 8.4 10.0 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4238 PF14022.6 KFM62716.1 - 0.6 9.6 4.2 0.75 9.3 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) CREPT PF16566.5 KFM62716.1 - 0.67 10.1 8.0 0.19 11.9 3.1 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour MT0933_antitox PF14013.6 KFM62716.1 - 0.82 10.0 10.3 0.46 10.8 1.7 3.0 3 0 0 3 3 2 0 MT0933-like antitoxin protein Terminase_2 PF03592.16 KFM62716.1 - 0.96 9.9 5.8 0.39 11.2 2.0 1.9 1 1 1 2 2 2 0 Terminase small subunit DUF1059 PF06348.11 KFM62716.1 - 1.3 9.3 6.1 3.5 7.9 0.2 3.6 3 1 1 4 4 3 0 Protein of unknown function (DUF1059) Remorin_C PF03763.13 KFM62716.1 - 1.4 8.8 8.3 0.55 10.1 5.1 2.0 2 1 0 2 2 1 0 Remorin, C-terminal region SICA_alpha PF12887.7 KFM62716.1 - 1.8 8.4 8.9 30 4.4 3.3 2.6 1 1 2 3 3 3 0 SICA extracellular alpha domain DUF4404 PF14357.6 KFM62716.1 - 1.9 9.2 9.1 0.38 11.4 3.4 2.5 1 1 3 4 4 3 0 Domain of unknown function (DUF4404) AKNA PF12443.8 KFM62716.1 - 2.7 8.7 5.3 1.1e+02 3.5 5.3 2.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor RNase_J_C PF17770.1 KFM62716.1 - 2.8 9.0 5.0 17 6.6 0.4 2.7 1 1 2 3 3 3 0 Ribonuclease J C-terminal domain RRF PF01765.19 KFM62716.1 - 3.1 7.7 11.0 6.5 6.7 7.8 2.1 1 1 1 2 2 2 0 Ribosome recycling factor LSM PF01423.22 KFM62717.1 - 5.9e-19 67.5 0.3 8e-19 67.1 0.3 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFM62717.1 - 0.0052 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Ran_BP1 PF00638.18 KFM62718.1 - 2.9e-51 172.9 0.2 2.9e-51 172.9 0.2 1.7 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KFM62718.1 - 3.4e-05 23.8 0.1 7.5e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 WH1 domain SH3_3 PF08239.11 KFM62719.1 - 0.018 15.3 0.0 0.05 13.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial SH3 domain WD40 PF00400.32 KFM62720.1 - 5.7e-11 42.8 11.1 1.8e-05 25.4 0.0 5.5 6 1 1 7 7 7 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KFM62720.1 - 1.3e-05 25.5 0.0 0.00099 19.5 0.0 3.0 2 0 0 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KFM62720.1 - 0.0027 18.0 0.0 2.9 8.3 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain cwf21 PF08312.12 KFM62721.1 - 1.4e-12 47.5 5.9 1.4e-12 47.5 5.9 2.4 2 1 0 2 2 2 1 cwf21 domain SRRM_C PF15230.6 KFM62722.1 - 1.3e-11 44.9 30.4 1.3e-11 44.9 30.4 13.2 8 3 5 14 14 14 1 Serine/arginine repetitive matrix protein C-terminus Exo_endo_phos PF03372.23 KFM62723.1 - 0.082 12.4 0.0 0.094 12.2 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-C2H2_2 PF12756.7 KFM62724.1 - 0.0095 16.3 2.0 0.0095 16.3 2.0 16.2 8 6 8 16 16 16 7 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFM62724.1 - 0.01 16.2 0.8 0.01 16.2 0.8 13.6 16 1 0 16 16 16 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM62724.1 - 0.012 16.4 7.4 0.037 14.9 0.7 23.7 25 0 0 25 25 25 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFM62724.1 - 0.064 13.6 0.3 0.064 13.6 0.3 18.2 16 4 1 18 18 18 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFM62724.1 - 0.087 13.3 0.3 0.087 13.3 0.3 22.6 24 0 0 24 24 24 0 Zinc finger, C2H2 type HTH_Tnp_Tc3_2 PF01498.18 KFM62725.1 - 2.5e-11 43.6 7.1 6.8e-11 42.3 7.1 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62725.1 - 1.4e-08 34.6 0.0 1.5e-06 28.0 0.0 3.1 2 1 0 3 3 3 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62725.1 - 2.7e-05 23.8 1.9 4e-05 23.3 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62725.1 - 0.00022 20.9 5.3 0.0015 18.3 0.2 3.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_12 PF08461.10 KFM62725.1 - 0.013 15.4 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_32 PF13565.6 KFM62725.1 - 0.028 15.0 5.9 0.065 13.8 4.3 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4 PF04545.16 KFM62725.1 - 0.041 13.4 1.0 0.095 12.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KFM62725.1 - 0.15 11.8 0.3 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_Tc3_2 PF01498.18 KFM62726.1 - 1.5e-10 41.1 2.9 1.5e-10 41.1 2.9 2.1 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM62726.1 - 1.4e-08 34.4 2.1 9.7e-07 28.4 0.6 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_3 PF13358.6 KFM62726.1 - 8.9e-08 32.0 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM62726.1 - 2.5e-07 30.3 3.8 0.00022 20.9 1.0 3.1 3 0 0 3 3 3 2 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM62726.1 - 0.00081 19.2 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Tc3 transposase Sigma70_r4_2 PF08281.12 KFM62726.1 - 0.01 15.5 0.0 0.055 13.2 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_3 PF01381.22 KFM62726.1 - 0.031 14.4 0.0 0.58 10.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM62726.1 - 0.038 14.0 0.4 8 6.5 0.0 2.6 2 1 1 3 3 3 0 Crp-like helix-turn-helix domain DUF2285 PF10074.9 KFM62726.1 - 3.6 8.3 8.2 0.21 12.2 1.6 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) HTH_29 PF13551.6 KFM62726.1 - 9.6 6.3 8.2 2.8 8.0 1.9 2.6 3 0 0 3 3 3 0 Winged helix-turn helix PetL PF05115.14 KFM62727.1 - 0.16 12.0 1.7 0.2 11.7 0.4 1.8 1 1 1 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) 7tm_1 PF00001.21 KFM62728.1 - 1.3e-38 132.8 0.3 2.1e-38 132.1 0.3 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FA_desaturase PF00487.24 KFM62728.1 - 0.19 11.5 0.2 2.6 7.8 0.1 2.0 2 0 0 2 2 2 0 Fatty acid desaturase Ig_3 PF13927.6 KFM62729.1 - 1.6e-15 57.4 0.0 4.6e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM62729.1 - 1.1e-12 47.8 0.0 8.3e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM62729.1 - 3e-12 46.7 0.0 6.9e-11 42.3 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.19 KFM62729.1 - 2.4e-09 37.3 10.6 2.4e-09 37.3 10.6 2.5 2 0 0 2 2 2 1 Thrombospondin type 1 domain ig PF00047.25 KFM62729.1 - 4.7e-07 29.9 0.0 3.9e-06 26.9 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 KFM62729.1 - 5e-05 23.4 0.1 0.0057 16.8 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM62729.1 - 0.0061 16.1 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain UPA PF17217.3 KFM62730.1 - 1.3e-44 151.5 0.1 2e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFM62730.1 - 7.6e-30 103.2 0.0 1.6e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFM62730.1 - 1e-18 67.3 0.0 2.1e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Death domain Trypan_PARP PF05887.11 KFM62731.1 - 3.8 7.5 18.4 0.21 11.6 12.1 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RtxA PF07634.11 KFM62732.1 - 3.1 8.5 7.4 4.5 8.0 0.6 4.3 4 0 0 4 4 4 0 RtxA repeat HTH_Tnp_Tc3_2 PF01498.18 KFM62733.1 - 6.2e-19 68.0 4.3 1.1e-18 67.3 1.4 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62733.1 - 3.7e-14 52.7 0.0 1.2e-13 51.1 0.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM62733.1 - 1.9e-07 31.6 4.6 3.7e-07 30.7 2.4 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM62733.1 - 0.00097 19.1 0.4 0.016 15.2 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KFM62733.1 - 0.0011 18.8 0.8 0.014 15.3 0.0 2.3 1 1 1 2 2 2 1 MarR family HTH_29 PF13551.6 KFM62733.1 - 0.0017 18.3 0.3 0.039 14.0 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM62733.1 - 0.0019 18.3 1.3 0.44 10.7 0.0 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62733.1 - 0.013 15.3 1.9 0.92 9.4 0.0 3.1 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 KFM62733.1 - 0.02 14.9 0.6 6.8 6.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 KFM62733.1 - 0.087 13.0 0.1 17 5.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_21 PF13276.6 KFM62733.1 - 0.13 12.4 0.5 1.6 9.0 0.5 2.5 1 1 1 2 2 2 0 HTH-like domain Mnd1 PF03962.15 KFM62734.1 - 7.5e-30 103.0 0.4 7.5e-30 103.0 0.4 2.4 3 0 0 3 3 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 KFM62734.1 - 8.1e-24 83.5 1.9 8.1e-24 83.5 1.9 2.5 2 0 0 2 2 2 1 Leucine zipper with capping helix domain GPP34 PF05719.11 KFM62734.1 - 0.0042 17.1 0.2 0.0054 16.8 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) FapA PF03961.13 KFM62734.1 - 0.0043 15.7 1.8 0.0058 15.3 1.8 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF745 PF05335.13 KFM62734.1 - 0.0055 16.5 2.0 0.0088 15.8 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) TrmB PF01978.19 KFM62734.1 - 0.01 15.7 0.1 0.078 12.9 0.0 2.4 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB CaM_bdg_C0 PF10562.9 KFM62734.1 - 0.015 15.3 0.6 0.042 13.9 0.6 1.7 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit FUR PF01475.19 KFM62734.1 - 0.017 15.3 0.3 0.036 14.2 0.1 1.7 1 1 0 1 1 1 0 Ferric uptake regulator family Prefoldin PF02996.17 KFM62734.1 - 0.021 14.7 2.8 0.074 13.0 0.1 2.6 2 1 0 2 2 2 0 Prefoldin subunit Penicillinase_R PF03965.16 KFM62734.1 - 0.025 15.0 0.2 0.04 14.3 0.2 1.5 1 1 0 1 1 1 0 Penicillinase repressor HBM PF16591.5 KFM62734.1 - 0.028 13.8 1.6 0.047 13.1 1.6 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain DUF5339 PF17274.2 KFM62734.1 - 0.039 14.8 0.4 0.039 14.8 0.4 1.9 2 1 0 2 2 1 0 Family of unknown function (DUF5339) DivIC PF04977.15 KFM62734.1 - 0.047 13.5 8.3 0.12 12.2 3.1 2.5 1 1 1 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.19 KFM62734.1 - 0.075 10.9 1.6 0.095 10.6 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.12 KFM62734.1 - 0.085 12.9 6.2 0.18 11.8 6.2 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF4407 PF14362.6 KFM62734.1 - 0.088 12.1 1.1 0.1 11.9 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) P4Ha_N PF08336.11 KFM62734.1 - 0.1 12.6 1.6 0.21 11.6 1.6 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Spc7 PF08317.11 KFM62734.1 - 0.11 11.4 9.7 4.3 6.1 9.5 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Hemerythrin PF01814.23 KFM62734.1 - 0.13 12.9 0.3 3 8.5 0.4 2.2 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Phage_GP20 PF06810.11 KFM62734.1 - 0.15 11.8 10.3 0.74 9.6 1.1 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 T3SSipB PF16535.5 KFM62734.1 - 0.18 12.3 5.1 0.48 10.9 5.0 1.7 1 1 0 1 1 1 0 Type III cell invasion protein SipB TPR_MLP1_2 PF07926.12 KFM62734.1 - 0.23 11.5 7.7 6.2 6.9 0.2 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FemAB PF02388.16 KFM62734.1 - 0.24 10.2 4.4 0.38 9.6 4.4 1.2 1 0 0 1 1 1 0 FemAB family ABC_tran_CTD PF16326.5 KFM62734.1 - 0.27 11.5 5.0 0.72 10.1 5.0 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain Halogen_Hydrol PF10112.9 KFM62734.1 - 0.3 11.1 4.8 4.9 7.1 1.6 2.5 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein FlxA PF14282.6 KFM62734.1 - 0.35 10.9 5.6 1.5 8.9 5.6 2.1 1 1 0 1 1 1 0 FlxA-like protein DPM3 PF08285.11 KFM62734.1 - 0.47 10.7 4.6 0.81 9.9 0.9 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SlyX PF04102.12 KFM62734.1 - 0.48 11.1 3.6 0.59 10.8 2.0 2.0 1 1 0 1 1 1 0 SlyX Pinin_SDK_N PF04697.13 KFM62734.1 - 0.67 10.6 7.1 0.31 11.7 1.7 2.2 1 1 1 2 2 2 0 pinin/SDK conserved region Atg14 PF10186.9 KFM62734.1 - 1.1 8.3 5.9 1.8 7.6 5.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2203 PF09969.9 KFM62734.1 - 1.3 9.8 5.7 0.76 10.5 2.9 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4140 PF13600.6 KFM62734.1 - 1.3 9.5 5.8 4.9 7.6 1.7 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Phage_1_1 PF08200.11 KFM62734.1 - 1.4 9.4 5.6 1.2 9.6 2.0 2.7 3 1 0 3 3 2 0 Bacteriophage 1.1 Protein DUF16 PF01519.16 KFM62734.1 - 2 8.9 8.2 14 6.2 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Csm1_N PF18504.1 KFM62734.1 - 3.2 8.1 10.8 0.47 10.8 3.2 2.8 1 1 0 2 2 2 0 Csm1 N-terminal domain TMPIT PF07851.13 KFM62734.1 - 4.1 6.6 5.5 1.2 8.3 2.5 1.7 2 0 0 2 2 2 0 TMPIT-like protein Cys_knot PF00007.22 KFM62737.1 - 2.7e-09 37.3 3.4 3e-09 37.1 3.4 1.1 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.15 KFM62737.1 - 0.0011 19.0 1.7 0.0015 18.5 1.7 1.3 1 0 0 1 1 1 1 DAN domain XRN1_DBM PF18245.1 KFM62738.1 - 0.078 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 5-3 exonuclease XRN1 DCP1-binding motif Pkinase PF00069.25 KFM62739.1 - 7.4e-25 87.8 0.1 1.5e-24 86.8 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM62739.1 - 2.3e-23 82.8 0.1 4.2e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFM62739.1 - 0.0013 18.9 0.4 0.0032 17.6 0.0 1.9 2 0 0 2 2 2 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_C PF00433.24 KFM62740.1 - 0.0001 22.9 0.0 0.00016 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase PF00069.25 KFM62740.1 - 0.01 15.3 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kelch_1 PF01344.25 KFM62742.1 - 8e-26 89.4 17.8 3.7e-12 45.6 0.0 5.7 5 1 0 5 5 5 3 Kelch motif BTB PF00651.31 KFM62742.1 - 1.5e-17 63.8 0.1 6e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.6 KFM62742.1 - 4.1e-15 55.4 13.0 1.7e-05 25.0 0.1 5.6 3 1 2 5 5 5 4 Kelch motif BACK PF07707.15 KFM62742.1 - 4.6e-13 49.2 0.2 8.9e-13 48.2 0.2 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFM62742.1 - 1.6e-12 46.8 3.5 0.00041 20.2 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 KFM62742.1 - 5.7e-07 29.7 0.6 0.027 14.7 0.2 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM62742.1 - 3.9e-06 26.7 1.2 0.082 12.9 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KFM62742.1 - 0.00016 21.6 6.9 0.078 13.0 0.0 5.0 4 1 1 5 5 5 2 Galactose oxidase, central domain Neuralized PF07177.12 KFM62743.1 - 1.2e-16 61.1 0.0 1.3e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 Neuralized Roc PF08477.13 KFM62744.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KFM62745.1 - 4.1e-10 39.8 0.6 5.4e-10 39.4 0.6 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain TIR_2 PF13676.6 KFM62746.1 - 7.3e-20 71.7 0.0 1.4e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 TIR domain Death PF00531.22 KFM62746.1 - 1.9e-12 47.2 0.0 3.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Death domain TIR PF01582.20 KFM62746.1 - 0.07 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 TIR domain Peptidase_S8 PF00082.22 KFM62748.1 - 3.2e-05 23.4 0.0 3.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Subtilase family Ribosomal_S4 PF00163.19 KFM62749.1 - 1.7e-08 35.2 1.9 2.2e-08 34.9 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain EGF PF00008.27 KFM62750.1 - 0.0011 19.3 5.5 0.0011 19.3 5.5 2.0 2 0 0 2 2 2 1 EGF-like domain EGF PF00008.27 KFM62751.1 - 2.6e-35 120.3 66.5 7.6e-08 32.5 7.2 5.4 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 KFM62751.1 - 1.5e-26 92.1 67.7 1.4e-08 35.0 8.3 6.2 6 0 0 6 6 6 5 Human growth factor-like EGF EGF_CA PF07645.15 KFM62751.1 - 6.5e-17 61.5 61.0 1.8e-06 28.0 4.8 5.2 4 1 1 5 5 5 5 Calcium-binding EGF domain EGF_3 PF12947.7 KFM62751.1 - 3.2e-11 43.2 59.8 0.0049 17.0 3.5 6.1 3 1 2 5 5 5 5 EGF domain EGF_2 PF07974.13 KFM62751.1 - 4e-11 43.1 72.1 0.00035 20.9 7.8 5.4 5 0 0 5 5 5 5 EGF-like domain FXa_inhibition PF14670.6 KFM62751.1 - 0.00016 21.9 61.3 0.032 14.5 7.5 5.7 3 1 2 5 5 5 5 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 KFM62751.1 - 0.00017 21.7 59.9 0.13 12.4 4.6 5.3 2 2 3 5 5 5 2 Laminin EGF domain EGF_MSP1_1 PF12946.7 KFM62751.1 - 0.026 14.6 3.9 0.026 14.6 3.9 5.5 5 1 0 5 5 5 0 MSP1 EGF domain 1 cEGF PF12662.7 KFM62751.1 - 0.05 13.5 58.9 0.05 13.5 0.9 7.4 7 2 0 7 7 7 0 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 KFM62751.1 - 0.12 12.7 49.7 0.72 10.2 3.2 5.3 5 0 0 5 5 5 0 Pvs28 EGF domain EGF PF00008.27 KFM62752.1 - 1.5e-06 28.3 4.9 2.8e-06 27.5 4.9 1.4 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFM62752.1 - 0.0019 18.7 2.8 0.0019 18.7 2.8 2.0 2 1 0 2 2 2 1 Human growth factor-like EGF Ank_2 PF12796.7 KFM62753.1 - 6.6e-36 122.8 14.4 1.7e-15 57.4 1.5 4.7 1 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.30 KFM62753.1 - 6.8e-27 92.7 9.8 0.00026 21.3 0.2 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFM62753.1 - 2.9e-26 91.2 9.9 3.8e-09 36.6 0.2 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM62753.1 - 1.1e-21 74.6 1.8 0.00078 19.7 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat DUF3454 PF11936.8 KFM62753.1 - 1.9e-21 76.2 23.3 1.9e-21 76.2 23.3 3.9 4 1 0 4 4 3 1 Domain of unknown function (DUF3454) Ank_4 PF13637.6 KFM62753.1 - 3.2e-21 75.4 3.4 3e-08 34.0 0.0 6.3 3 1 4 7 7 6 4 Ankyrin repeats (many copies) NOD PF06816.13 KFM62753.1 - 4.9e-18 64.5 0.0 9.8e-18 63.5 0.0 1.6 1 0 0 1 1 1 1 NOTCH protein NODP PF07684.12 KFM62753.1 - 5.5e-18 64.9 0.3 1.4e-17 63.5 0.3 1.8 1 0 0 1 1 1 1 NOTCH protein PUB_1 PF18486.1 KFM62753.1 - 0.083 12.8 0.5 2.5 8.0 0.1 2.8 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain DUF4834 PF16118.5 KFM62753.1 - 0.14 13.1 0.3 2.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) VIR_N PF15912.5 KFM62753.1 - 1.8 8.1 6.9 5 6.6 6.9 1.7 1 0 0 1 1 1 0 Virilizer, N-terminal PAP2 PF01569.21 KFM62755.1 - 1.3e-17 63.9 7.7 3.8e-17 62.3 7.7 1.8 1 1 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 KFM62755.1 - 0.002 17.5 11.7 0.0034 16.7 11.7 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family SpoVAB PF13782.6 KFM62755.1 - 0.065 13.5 0.9 0.13 12.6 0.9 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AB DUF212 PF02681.14 KFM62755.1 - 0.07 13.3 0.1 7 6.8 0.0 2.5 1 1 1 2 2 2 0 Divergent PAP2 family Carn_acyltransf PF00755.20 KFM62756.1 - 2.6e-81 274.0 0.1 2.9e-81 273.9 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.20 KFM62757.1 - 3e-50 171.5 0.0 3.3e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase HTH_Tnp_Tc3_2 PF01498.18 KFM62758.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62758.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62758.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62758.1 - 0.0024 17.6 0.6 0.0069 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62758.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62759.1 - 1.9e-13 50.5 1.8 2.2e-13 50.2 0.7 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62759.1 - 4.2e-07 29.8 0.0 1.3e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease PH PF00169.29 KFM62761.1 - 3.3e-05 24.4 0.8 4.3e-05 24.0 0.8 1.4 1 1 0 1 1 1 1 PH domain RRM_1 PF00076.22 KFM62762.1 - 1.8e-10 40.5 0.0 2.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM62762.1 - 0.0012 18.4 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_1 PF00561.20 KFM62763.1 - 1.7e-17 63.9 0.0 1.8e-16 60.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM62763.1 - 1.2e-12 48.9 0.0 1.7e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM62763.1 - 1.9e-12 46.9 0.0 5.2e-12 45.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFM62763.1 - 5.1e-05 22.1 0.0 7.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 KFM62763.1 - 0.00073 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KFM62763.1 - 0.0028 17.8 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KFM62763.1 - 0.0084 15.8 0.0 0.027 14.2 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein DUF915 PF06028.11 KFM62763.1 - 0.01 15.2 0.0 0.025 13.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 KFM62763.1 - 0.01 15.4 0.1 0.015 14.8 0.1 1.5 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 KFM62763.1 - 0.012 15.4 0.0 0.037 13.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFM62763.1 - 0.028 14.3 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KFM62763.1 - 0.037 12.9 0.0 0.078 11.9 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Na_H_Exchanger PF00999.21 KFM62765.1 - 3.7e-21 75.4 11.8 4.4e-21 75.1 11.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PHO4 PF01384.20 KFM62765.1 - 0.0061 15.7 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Phosphate transporter family Na_H_Exchanger PF00999.21 KFM62766.1 - 3.6e-34 118.2 12.6 3.9e-34 118.1 12.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 KFM62766.1 - 1.1 9.7 5.0 4.1 7.8 0.5 2.9 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Transposase_1 PF01359.18 KFM62767.1 - 6.3e-14 51.6 0.4 1.4e-13 50.5 0.1 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM62767.1 - 2.7e-09 36.9 0.0 4.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Got1 PF04178.12 KFM62769.1 - 3.4e-18 66.1 14.1 1.1e-17 64.5 13.0 1.9 1 1 1 2 2 2 2 Got1/Sft2-like family TMEM43 PF07787.12 KFM62769.1 - 0.65 9.3 1.8 0.81 9.0 1.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 SAM_2 PF07647.17 KFM62770.1 - 3.7e-11 43.0 0.2 6e-11 42.3 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM62770.1 - 2.3e-09 37.6 0.2 3.9e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFM62770.1 - 4.8e-05 23.3 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Tcf25 PF04910.14 KFM62770.1 - 0.018 14.1 0.5 0.021 13.9 0.5 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Peptidase_C1 PF00112.23 KFM62771.1 - 1.1e-08 35.4 0.0 1.3e-08 35.3 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.23 KFM62772.1 - 3.6e-12 46.9 0.0 7.7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Somatomedin_B PF01033.17 KFM62772.1 - 0.0021 18.4 17.9 0.0021 18.4 17.9 2.4 2 0 0 2 2 2 1 Somatomedin B domain DUF1496 PF07383.12 KFM62772.1 - 0.021 14.4 0.4 0.053 13.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) Propeptide_C1 PF08127.13 KFM62772.1 - 0.033 14.1 0.2 0.057 13.3 0.2 1.3 1 0 0 1 1 1 0 Peptidase family C1 propeptide TPR_2 PF07719.17 KFM62775.1 - 4.1e-25 85.8 11.3 4.2e-05 23.3 0.3 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFM62775.1 - 1.9e-24 84.4 12.6 6.3e-05 22.6 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat DnaJ PF00226.31 KFM62775.1 - 5e-22 77.8 0.7 1.4e-21 76.4 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 KFM62775.1 - 1.3e-19 69.6 8.3 5.1e-06 26.1 0.0 6.5 3 2 3 6 6 6 5 TPR repeat TPR_8 PF13181.6 KFM62775.1 - 1.6e-17 62.2 7.4 0.0078 16.3 0.0 7.2 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM62775.1 - 1.3e-14 54.4 12.8 6.6e-05 23.3 0.2 6.2 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFM62775.1 - 1.8e-14 54.1 7.0 8.1e-05 23.2 0.0 6.3 3 3 2 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFM62775.1 - 3.2e-14 52.8 6.1 0.0014 18.7 0.4 5.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFM62775.1 - 2e-12 46.8 12.6 0.056 14.3 0.0 8.3 4 3 6 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFM62775.1 - 1e-11 44.3 8.7 0.0043 17.3 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM62775.1 - 4e-09 36.6 15.2 0.017 15.4 0.8 6.2 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_20 PF14561.6 KFM62775.1 - 1.5e-08 34.8 6.0 0.12 12.7 0.0 4.7 3 2 0 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 KFM62775.1 - 2.4e-06 27.4 9.1 0.00092 19.0 0.1 3.9 3 2 2 5 5 5 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 KFM62775.1 - 2.8e-06 27.5 11.9 0.018 15.2 0.6 4.1 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFM62775.1 - 3.3e-06 26.5 0.3 0.47 9.6 0.0 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM62775.1 - 5.8e-06 26.6 6.8 7.9 7.4 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat NARP1 PF12569.8 KFM62775.1 - 0.00016 20.8 9.4 0.071 12.0 0.0 3.3 2 2 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 KFM62775.1 - 0.00035 20.4 8.3 20 5.5 0.4 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KFM62775.1 - 0.045 13.8 0.2 0.45 10.6 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 SHNi-TPR PF10516.9 KFM62775.1 - 0.13 11.7 0.2 0.13 11.7 0.2 3.4 5 0 0 5 5 5 0 SHNi-TPR ChAPs PF09295.10 KFM62775.1 - 0.15 11.0 0.3 2.5 7.0 0.0 2.7 2 2 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.9 KFM62775.1 - 0.16 11.7 6.4 4.1 7.1 2.2 3.9 2 2 1 3 3 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 KFM62775.1 - 0.42 10.6 13.2 2.4 8.2 0.1 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat 7tm_1 PF00001.21 KFM62776.1 - 4.2e-47 160.7 11.7 5e-47 160.4 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM62776.1 - 1.4e-06 27.9 7.3 2.1e-06 27.3 6.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM62776.1 - 2.1e-06 27.6 9.8 3.7e-06 26.8 9.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx ATP-synt_J PF04911.12 KFM62776.1 - 0.081 12.5 0.4 0.25 10.9 0.4 1.9 1 0 0 1 1 1 0 ATP synthase j chain 7tm_4 PF13853.6 KFM62776.1 - 0.31 10.7 7.6 0.2 11.3 0.9 2.8 2 1 1 3 3 3 0 Olfactory receptor Bac_export_2 PF01312.19 KFM62776.1 - 4.2 6.5 5.6 0.86 8.7 2.3 1.6 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family zf-C2H2 PF00096.26 KFM62777.1 - 3.2e-15 55.6 44.1 0.00092 19.5 0.1 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM62777.1 - 9.1e-15 54.1 42.6 3.3e-07 29.9 3.7 6.5 6 0 0 6 6 6 5 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM62777.1 - 5.3e-12 45.5 45.4 0.023 15.5 0.3 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM62777.1 - 1.6e-06 28.3 61.6 3.1e-05 24.2 2.9 8.3 7 2 0 7 7 7 3 Zinc-finger double domain zf-Di19 PF05605.12 KFM62777.1 - 1.8e-06 28.1 24.9 0.041 14.2 0.5 5.6 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KFM62777.1 - 3.7e-05 23.3 24.8 1.8 8.3 0.2 6.3 5 1 1 6 6 6 5 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFM62777.1 - 0.1 12.9 38.6 0.91 9.9 3.0 5.9 2 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.13 KFM62777.1 - 0.12 12.4 25.2 0.063 13.3 4.0 4.2 2 1 2 4 4 4 0 Transcription elongation factor Elf1 like OrsD PF12013.8 KFM62777.1 - 0.17 12.3 31.5 2.3 8.7 0.4 5.8 3 2 3 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D DZR PF12773.7 KFM62777.1 - 5.6 7.1 20.4 0.77 9.8 1.3 3.8 3 1 0 3 3 3 0 Double zinc ribbon Filamin PF00630.19 KFM62778.1 - 7.1e-112 367.3 18.9 1.5e-15 57.9 0.3 9.3 9 0 0 9 9 9 9 Filamin/ABP280 repeat Y_Y_Y PF07495.13 KFM62778.1 - 5.9e-12 45.4 1.7 0.26 11.3 0.0 6.6 6 0 0 6 6 6 3 Y_Y_Y domain PKD PF00801.20 KFM62778.1 - 2.3e-05 24.2 0.1 5.5 6.9 0.0 6.5 7 0 0 7 7 7 1 PKD domain Big_3_5 PF16640.5 KFM62778.1 - 0.00018 21.6 2.3 4.5 7.5 0.0 5.0 4 0 0 4 4 4 1 Bacterial Ig-like domain (group 3) DUF5060 PF16586.5 KFM62778.1 - 0.00069 19.9 0.0 1.3e+02 3.0 0.0 5.8 5 0 0 5 5 5 0 Domain of unknown function (DUF5060) YtkA PF13115.6 KFM62778.1 - 0.0014 19.2 0.0 16 6.2 0.0 5.0 5 0 0 5 5 4 0 YtkA-like CarboxypepD_reg PF13620.6 KFM62778.1 - 0.0023 18.1 0.4 2.3 8.6 0.1 3.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Invasin_D3 PF09134.10 KFM62778.1 - 0.05 13.9 3.2 1.5 9.2 0.1 4.3 5 1 1 6 6 4 0 Invasin, domain 3 Wzt_C PF14524.6 KFM62778.1 - 0.066 13.2 0.1 22 5.0 0.0 4.0 4 1 1 5 5 5 0 Wzt C-terminal domain Tyosinase_C PF18132.1 KFM62778.1 - 0.12 13.1 0.4 16 6.2 0.0 3.7 4 0 0 4 4 4 0 Tyosinase C-terminal domain PapC_N PF13954.6 KFM62778.1 - 0.16 12.0 0.0 44 4.0 0.0 3.5 3 0 0 3 3 3 0 PapC N-terminal domain DUF4115 PF13464.6 KFM62778.1 - 0.18 12.0 0.1 44 4.4 0.0 4.0 4 0 0 4 4 3 0 Domain of unknown function (DUF4115) RIO1 PF01163.22 KFM62779.1 - 2e-54 184.1 0.6 2.6e-54 183.7 0.6 1.1 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KFM62779.1 - 2.9e-29 101.1 0.0 8.6e-29 99.6 0.0 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KFM62779.1 - 1.1e-10 41.8 1.5 0.00038 20.4 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFM62779.1 - 1.1e-07 31.5 0.3 0.00028 20.3 0.1 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFM62779.1 - 0.00085 18.8 0.3 0.0018 17.7 0.3 1.5 1 1 0 1 1 1 1 Protein kinase domain DUF4640 PF15480.6 KFM62780.1 - 0.051 13.3 8.4 0.059 13.1 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) GAGA_bind PF06217.12 KFM62780.1 - 0.71 10.1 8.9 0.74 10.0 8.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Spore_II_R PF09551.10 KFM62780.1 - 2.2 8.8 8.0 2.7 8.4 7.9 1.3 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Peptidase_S49_N PF08496.10 KFM62780.1 - 6.9 6.7 11.5 8.7 6.4 11.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TP_methylase PF00590.20 KFM62781.1 - 1.1e-23 84.3 0.0 3.5e-23 82.7 0.0 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ada3 PF10198.9 KFM62782.1 - 3.5e-15 56.3 6.2 5.7e-15 55.6 6.2 1.5 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DFF40 PF09230.10 KFM62783.1 - 0.0029 17.3 0.2 0.0048 16.6 0.2 1.6 1 1 0 1 1 1 1 DNA fragmentation factor 40 kDa DUF4170 PF13773.6 KFM62784.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) AKAP2_C PF15304.6 KFM62786.1 - 6.5e-07 29.0 46.4 0.0029 17.0 12.6 4.8 1 1 3 4 4 4 4 A-kinase anchor protein 2 C-terminus HSL_N PF06350.12 KFM62787.1 - 3.6e-42 144.4 0.1 6e-42 143.7 0.1 1.4 1 0 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.13 KFM62787.1 - 4.8e-35 121.3 0.0 2.7e-26 92.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFM62787.1 - 1.6e-08 33.8 0.0 2.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase DEAD PF00270.29 KFM62790.1 - 2.8e-15 56.5 0.0 3.4e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM62790.1 - 3.7e-15 56.4 0.0 5.2e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFM62790.1 - 0.00059 19.2 0.0 0.00086 18.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 KFM62790.1 - 0.0017 18.1 0.0 0.0029 17.3 0.0 1.3 1 1 0 1 1 1 1 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 KFM62790.1 - 0.0083 15.9 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFM62790.1 - 0.023 14.9 0.0 0.049 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KFM62790.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 KFM62790.1 - 0.091 13.1 0.1 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain PIG-H PF10181.9 KFM62790.1 - 0.16 11.8 0.4 0.99 9.3 0.1 2.3 2 2 0 2 2 2 0 GPI-GlcNAc transferase complex, PIG-H component zf-C2H2 PF00096.26 KFM62791.1 - 1e-14 54.1 16.9 0.00013 22.2 4.2 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM62791.1 - 3e-14 52.7 6.7 1.2e-07 31.8 0.2 4.9 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM62791.1 - 2.1e-10 40.6 17.1 0.0014 19.3 2.4 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM62791.1 - 0.00058 20.1 1.2 12 6.3 0.2 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM62791.1 - 0.0062 16.5 5.1 0.66 10.0 0.6 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM62791.1 - 0.01 15.7 10.2 0.62 10.0 0.5 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-BED PF02892.15 KFM62791.1 - 0.014 15.4 7.5 0.025 14.6 2.7 2.9 1 1 1 2 2 2 0 BED zinc finger Zf_RING PF16744.5 KFM62791.1 - 0.087 13.0 1.1 0.74 10.0 0.9 2.2 1 1 1 2 2 2 0 KIAA1045 RING finger zf-H2C2_5 PF13909.6 KFM62791.1 - 0.18 11.6 0.1 0.18 11.6 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM62791.1 - 0.99 9.2 6.8 18 5.2 0.1 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KFM62791.1 - 1.1 9.7 4.7 30 5.2 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-CHY PF05495.12 KFM62791.1 - 1.2 9.7 5.2 6.6 7.3 5.2 2.1 1 1 0 1 1 1 0 CHY zinc finger zf-AN1 PF01428.16 KFM62791.1 - 3.9 7.7 6.0 15 5.9 0.7 2.7 1 1 1 2 2 2 0 AN1-like Zinc finger Vps51 PF08700.11 KFM62792.1 - 3.9e-26 91.0 3.8 3.9e-26 91.0 3.8 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 KFM62792.1 - 7.5e-20 71.5 2.1 1.3e-19 70.7 2.1 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 KFM62792.1 - 3.2e-14 52.4 7.4 1.3e-13 50.3 5.9 1.9 2 0 0 2 2 2 1 Dor1-like family Vps54_N PF10475.9 KFM62792.1 - 1.4e-10 41.0 6.1 2.1e-10 40.4 6.1 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 KFM62792.1 - 1.2e-08 35.1 4.6 2e-08 34.4 0.4 2.6 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 KFM62792.1 - 8.1e-07 28.3 3.9 9.7e-07 28.1 3.9 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal COG5 PF10392.9 KFM62792.1 - 0.00063 19.9 1.4 0.00063 19.9 1.4 2.4 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 KFM62792.1 - 0.0014 18.7 4.3 0.0023 18.0 0.6 2.5 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus YxiJ PF14176.6 KFM62792.1 - 0.0014 19.1 0.4 0.0014 19.1 0.4 2.5 2 1 1 3 3 3 1 YxiJ-like protein BLOC1S3 PF15753.5 KFM62792.1 - 0.015 15.5 0.8 0.029 14.5 0.2 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 YkyA PF10368.9 KFM62792.1 - 0.026 14.2 7.9 0.036 13.7 2.8 2.6 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein CaMBD PF02888.16 KFM62792.1 - 0.037 14.2 0.7 0.077 13.2 0.7 1.5 1 0 0 1 1 1 0 Calmodulin binding domain DUF1394 PF07159.12 KFM62792.1 - 0.041 13.1 6.6 0.63 9.2 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1394) GIT_CC PF16559.5 KFM62792.1 - 0.073 12.9 5.9 0.13 12.1 4.5 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HEPN PF05168.14 KFM62792.1 - 0.084 13.0 3.2 3.2 7.9 0.3 2.6 2 1 0 2 2 2 0 HEPN domain SKA2 PF16740.5 KFM62792.1 - 0.15 11.9 11.0 1.5 8.6 3.3 3.0 2 2 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF2120 PF09893.9 KFM62792.1 - 0.23 11.6 4.5 0.21 11.7 1.0 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Occludin_ELL PF07303.13 KFM62792.1 - 0.23 12.2 7.0 0.38 11.5 0.1 3.2 2 2 1 3 3 3 0 Occludin homology domain CENP-F_leu_zip PF10473.9 KFM62792.1 - 0.31 11.0 12.9 0.034 14.2 3.9 2.8 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GlcNAc-1_reg PF18440.1 KFM62792.1 - 0.45 10.8 3.2 0.43 10.8 0.5 2.4 2 1 1 3 3 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain HIP1_clath_bdg PF16515.5 KFM62792.1 - 1.7 9.3 12.9 0.05 14.2 3.4 2.7 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YlqD PF11068.8 KFM62792.1 - 2.5 8.5 12.5 0.26 11.7 3.4 2.9 2 1 0 3 3 3 0 YlqD protein DASH_Dad3 PF08656.10 KFM62792.1 - 3.1 8.0 12.4 25 5.0 4.7 3.7 2 2 0 2 2 2 0 DASH complex subunit Dad3 PI-PLC-X PF00388.19 KFM62794.1 - 1.2e-63 213.0 0.0 2.7e-63 211.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFM62794.1 - 3e-39 133.9 0.2 7.7e-36 122.9 0.1 2.9 2 0 0 2 2 2 2 Phosphatidylinositol-specific phospholipase C, Y domain RasGEF PF00617.19 KFM62794.1 - 1.5e-23 83.9 0.0 4.3e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 RasGEF domain RA PF00788.23 KFM62794.1 - 6.8e-22 77.9 0.2 1.2e-09 38.7 0.0 2.7 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain FERM_M PF00373.18 KFM62794.1 - 8.2e-11 42.3 0.1 2.4e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 FERM central domain C2 PF00168.30 KFM62794.1 - 4.9e-09 36.4 0.0 1.3e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 KFM62794.1 - 2.9e-07 30.9 0.0 1.1e-06 29.0 0.0 2.1 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like Skp1 PF01466.19 KFM62794.1 - 0.021 14.9 1.9 0.084 13.0 1.9 2.0 1 0 0 1 1 1 0 Skp1 family, dimerisation domain YopE PF03545.13 KFM62794.1 - 0.1 12.8 0.0 9.1 6.5 0.0 3.0 3 0 0 3 3 3 0 Yersinia virulence determinant (YopE) LAT PF15234.6 KFM62794.1 - 0.5 10.1 7.2 0.035 13.9 1.5 1.9 2 0 0 2 2 2 0 Linker for activation of T-cells Tubulin_3 PF14881.6 KFM62795.1 - 1.4e-11 44.4 0.0 2.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KFM62795.1 - 6.5e-06 26.5 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain HTH_Tnp_Tc3_2 PF01498.18 KFM62797.1 - 1.2e-19 70.3 3.8 3.8e-19 68.7 2.1 2.3 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM62797.1 - 1.4e-07 32.0 4.3 2.4e-07 31.3 2.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KFM62797.1 - 1.7e-07 31.2 0.9 0.0001 22.3 0.0 2.8 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM62797.1 - 1e-06 28.4 3.7 1.8e-05 24.4 0.0 3.0 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM62797.1 - 1.4e-06 28.2 0.5 2.7e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM62797.1 - 1.5e-05 25.0 7.7 5.3e-05 23.3 0.2 3.0 3 1 0 3 3 3 1 Helix-turn-helix domain MarR_2 PF12802.7 KFM62797.1 - 8.6e-05 22.3 0.8 0.0011 18.8 0.0 2.4 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM62797.1 - 0.00064 19.6 0.4 0.012 15.6 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM62797.1 - 0.013 15.2 0.1 0.076 12.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM62797.1 - 0.032 14.3 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM62797.1 - 0.051 13.8 0.1 9.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM62797.1 - 0.086 12.4 0.2 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM62797.1 - 0.1 12.7 0.0 21 5.3 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM62797.1 - 0.12 12.1 3.8 1.1 9.1 0.0 3.1 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain TrmB PF01978.19 KFM62797.1 - 0.13 12.2 0.1 5.4 7.0 0.0 2.4 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Tnp_ISL3 PF13542.6 KFM62797.1 - 0.61 9.5 3.6 5.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF3852 PF12963.7 KFM62798.1 - 0.078 13.3 0.6 0.18 12.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) DUF2448 PF10476.9 KFM62798.1 - 0.48 10.3 2.0 15 5.4 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) RIFIN PF02009.16 KFM62798.1 - 2.5 7.9 20.9 0.03 14.2 11.3 2.1 1 1 0 2 2 2 0 Rifin DGF-1_C PF11040.8 KFM62799.1 - 0.1 12.6 1.1 0.79 9.8 0.0 2.4 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DDE_3 PF13358.6 KFM62800.1 - 3.1e-13 49.7 0.0 5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62800.1 - 0.0012 19.1 1.4 0.013 15.7 1.4 2.3 1 1 0 1 1 1 1 Transposase WbqC PF08889.11 KFM62800.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 WbqC-like protein family Bunya_NS-S PF01104.17 KFM62801.1 - 0.028 14.2 1.6 0.078 12.8 1.6 1.9 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s Ank_2 PF12796.7 KFM62802.1 - 3.6e-11 43.5 0.1 1.1e-10 42.0 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM62802.1 - 7.2e-09 35.7 0.4 3e-05 24.3 0.4 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFM62802.1 - 2.6e-07 30.4 0.3 0.014 15.8 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFM62802.1 - 8.1e-07 29.5 0.1 2.7e-06 27.8 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM62802.1 - 0.00015 22.0 0.3 0.083 13.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3492 PF11997.8 KFM62802.1 - 0.36 10.5 2.9 3.3 7.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3492) PI3_PI4_kinase PF00454.27 KFM62804.1 - 3.4e-06 27.1 0.1 4.1e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase U3_assoc_6 PF08640.11 KFM62805.1 - 3.3e-24 84.7 10.2 5.7e-24 84.0 10.2 1.3 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_19 PF14559.6 KFM62805.1 - 0.0002 21.8 0.0 0.078 13.5 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM62805.1 - 0.00028 21.5 0.2 0.68 10.9 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat NRDE-2 PF08424.10 KFM62805.1 - 0.0012 18.0 6.1 0.0015 17.7 6.1 1.1 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference Ceramidase PF05875.12 KFM62805.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Ceramidase Suf PF05843.14 KFM62805.1 - 0.015 15.3 0.9 0.027 14.4 0.1 1.6 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Peptidase_C1 PF00112.23 KFM62807.1 - 3.6e-88 295.3 6.4 5.4e-88 294.7 6.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM62807.1 - 5.2e-10 39.6 3.5 5.2e-10 39.6 3.5 1.7 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM62807.1 - 9.4e-06 24.6 1.5 0.0034 16.2 0.6 2.2 2 0 0 2 2 2 2 Peptidase C1-like family RINGv PF12906.7 KFM62809.1 - 2.5e-12 46.7 13.9 7e-12 45.3 13.9 1.9 1 0 0 1 1 1 1 RING-variant domain Cyclin_N PF00134.23 KFM62811.1 - 1.1e-09 38.1 0.0 1.5e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFM62812.1 - 1.1e-05 25.6 0.0 2.4e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KFM62812.1 - 0.032 14.0 0.0 0.062 13.1 0.0 1.4 1 1 0 1 1 1 0 Cyclin, N-terminal domain zf-H2C2_2 PF13465.6 KFM62813.1 - 1.2e-75 246.8 87.1 2e-08 34.3 0.2 11.1 11 0 0 11 11 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62813.1 - 1.7e-54 179.3 100.1 3.4e-06 27.2 4.3 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62813.1 - 4.3e-36 120.5 89.0 0.0013 19.4 1.1 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM62813.1 - 4.1e-33 112.8 92.5 0.00041 20.6 2.8 10.3 10 0 0 10 10 10 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM62813.1 - 1e-24 86.2 66.8 0.0018 18.5 0.6 10.3 10 0 0 10 10 10 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM62813.1 - 7.6e-19 67.2 72.2 0.036 14.1 0.8 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM62813.1 - 3.6e-11 42.7 40.9 0.3 11.0 0.2 10.5 10 0 0 10 10 10 5 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM62813.1 - 3.2e-09 36.8 43.8 3.1 8.0 0.1 10.3 10 0 0 10 10 10 4 DBF zinc finger DUF2256 PF10013.9 KFM62813.1 - 1.3e-08 34.8 33.4 3.7 7.8 0.2 10.1 10 0 0 10 10 10 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_5 PF13909.6 KFM62813.1 - 5.1e-08 32.5 73.9 0.085 12.6 0.4 10.4 10 0 0 10 10 10 7 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM62813.1 - 3.7e-07 30.1 47.2 0.16 12.0 1.0 10.2 5 4 6 11 11 11 3 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM62813.1 - 1.1e-05 25.5 48.2 0.017 15.2 8.7 4.5 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_9 PF16293.5 KFM62813.1 - 9.7e-05 22.1 54.3 3.8 7.4 0.4 10.0 2 2 8 10 10 10 2 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM62813.1 - 0.00031 21.4 46.8 0.59 10.9 1.7 5.2 2 1 3 5 5 5 4 zinc-ribbon family BolA PF01722.18 KFM62813.1 - 0.00044 20.5 24.1 0.28 11.5 0.1 6.5 1 1 7 8 8 8 2 BolA-like protein zf-C2H2_2 PF12756.7 KFM62813.1 - 0.0018 18.6 82.4 1.8 9.0 2.7 9.8 1 1 8 9 9 9 3 C2H2 type zinc-finger (2 copies) DUF1493 PF07377.12 KFM62813.1 - 0.0033 17.9 0.2 1 9.9 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1493) ADK_lid PF05191.14 KFM62813.1 - 0.012 15.6 45.6 0.73 9.9 2.3 7.5 3 3 5 8 8 8 0 Adenylate kinase, active site lid zf-CHCC PF10276.9 KFM62813.1 - 0.013 15.5 18.4 42 4.3 0.0 8.5 10 0 0 10 10 10 0 Zinc-finger domain Ring_hydroxyl_B PF00866.18 KFM62813.1 - 0.025 14.6 0.0 1.8 8.6 0.0 2.9 2 1 0 3 3 3 0 Ring hydroxylating beta subunit zf-C2H2_11 PF16622.5 KFM62813.1 - 0.054 13.3 1.1 0.054 13.3 1.1 9.1 10 0 0 10 10 10 0 zinc-finger C2H2-type GAGA PF09237.11 KFM62813.1 - 0.079 12.8 25.3 4.6 7.1 0.6 7.1 2 2 5 8 8 8 0 GAGA factor IGPD PF00475.18 KFM62813.1 - 0.087 13.1 23.0 1.1 9.6 1.2 6.0 1 1 4 7 7 7 0 Imidazoleglycerol-phosphate dehydratase C1_1 PF00130.22 KFM62813.1 - 0.37 10.7 62.7 5.6 6.9 1.2 9.4 1 1 6 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD_kinase PF01513.21 KFM62813.1 - 0.54 9.4 4.8 66 2.6 4.8 3.1 1 1 0 1 1 1 0 ATP-NAD kinase Baculo_IE-1 PF05290.11 KFM62813.1 - 1.1 9.2 39.3 28 4.7 2.0 7.3 1 1 3 5 5 5 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 KFM62813.1 - 1.2 9.3 59.9 5 7.3 10.8 6.3 1 1 5 6 6 6 0 FYVE zinc finger FAM83 PF07894.12 KFM62813.1 - 2.3 7.7 9.0 1.4 8.5 0.8 2.8 1 1 2 3 3 3 0 FAM83 A-H YyzF PF14116.6 KFM62813.1 - 2.3 8.3 40.6 17 5.6 0.4 9.5 10 0 0 10 10 10 0 YyzF-like protein HEPPP_synt_1 PF07307.11 KFM62813.1 - 3.4 7.2 5.9 1.5 8.4 0.6 2.4 1 1 2 3 3 3 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 HNH PF01844.23 KFM62813.1 - 7.4 6.8 54.6 3.9 7.7 0.1 10.0 10 0 0 10 10 10 0 HNH endonuclease EGF PF00008.27 KFM62814.1 - 3.4e-08 33.6 7.5 3.4e-08 33.6 7.5 1.8 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 KFM62814.1 - 9.9e-05 22.8 6.3 9.9e-05 22.8 6.3 2.5 2 0 0 2 2 2 1 Human growth factor-like EGF Laminin_G_2 PF02210.24 KFM62814.1 - 0.00033 21.2 0.0 0.00054 20.5 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain EGF_CA PF07645.15 KFM62814.1 - 0.0029 17.8 8.3 0.0066 16.6 8.3 1.6 1 1 0 1 1 1 1 Calcium-binding EGF domain Laminin_G_1 PF00054.23 KFM62814.1 - 0.021 15.0 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Laminin G domain EGF_2 PF07974.13 KFM62814.1 - 1.3 9.4 11.1 7.2 7.1 11.1 2.1 1 1 0 1 1 1 0 EGF-like domain FXa_inhibition PF14670.6 KFM62814.1 - 2.6 8.4 9.4 10 6.5 9.4 2.0 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFM62814.1 - 9.3 6.3 9.0 0.19 11.7 1.5 2.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like GAIN PF16489.5 KFM62815.1 - 0.025 14.0 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain F420_ligase PF01996.16 KFM62815.1 - 0.099 12.0 0.0 0.099 12.0 0.0 1.0 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase RNase_H PF00075.24 KFM62817.1 - 7.2e-08 32.7 0.0 2.4e-07 31.0 0.0 1.9 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 KFM62817.1 - 0.00051 19.9 0.0 0.00089 19.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Tub PF01167.18 KFM62819.1 - 6.7e-29 101.3 0.0 1.1e-28 100.7 0.0 1.3 1 0 0 1 1 1 1 Tub family Tub_N PF16322.5 KFM62819.1 - 5.1e-09 36.9 7.7 4.3e-08 33.8 7.7 2.2 1 1 0 1 1 1 1 Tubby N-terminal Carm_PH PF17888.1 KFM62820.1 - 1.8e-35 121.1 0.3 2.5e-35 120.7 0.3 1.2 1 0 0 1 1 1 1 Carmil pleckstrin homology domain CARMIL_C PF16000.5 KFM62821.1 - 1.5e-56 192.3 11.3 3.6e-55 187.8 11.3 2.6 1 1 0 1 1 1 1 CARMIL C-terminus LRR_6 PF13516.6 KFM62821.1 - 8.4e-09 34.8 28.5 0.022 14.8 0.1 10.7 12 0 0 12 12 12 2 Leucine Rich repeat LRR_4 PF12799.7 KFM62821.1 - 3.3e-07 30.5 25.4 0.56 10.7 0.2 8.1 4 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM62821.1 - 6.7e-05 22.9 13.6 2.6 9.0 0.4 9.5 10 1 0 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.6 KFM62821.1 - 2.7 7.8 24.5 11 5.8 0.4 8.1 8 3 1 9 9 9 0 Leucine rich repeat HIP1_clath_bdg PF16515.5 KFM62821.1 - 8.8 7.0 6.7 2.7 8.7 3.2 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BTB PF00651.31 KFM62823.1 - 4.2e-21 75.3 7.7 1.9e-20 73.2 1.8 3.0 2 1 1 3 3 3 2 BTB/POZ domain zf-C3HC4_2 PF13923.6 KFM62824.1 - 2.8e-11 43.1 6.6 3.8e-11 42.7 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM62824.1 - 7e-10 38.6 7.4 9.4e-10 38.2 7.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM62824.1 - 9.7e-08 32.2 7.1 1.3e-07 31.8 7.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM62824.1 - 3.6e-07 29.9 7.7 4.8e-07 29.5 7.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM62824.1 - 2.6e-05 24.4 4.5 3.9e-05 23.9 4.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM62824.1 - 2.9e-05 23.9 10.5 0.00011 22.1 9.7 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM62824.1 - 7.2e-05 22.9 6.9 0.00015 21.8 7.0 1.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFM62824.1 - 0.00011 22.2 3.7 0.00011 22.2 3.7 1.7 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM62824.1 - 0.00012 21.8 6.1 0.00022 21.0 6.1 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KFM62824.1 - 0.0077 16.0 4.0 0.0095 15.7 4.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFM62824.1 - 0.012 15.7 5.3 0.017 15.2 5.3 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 KFM62824.1 - 0.033 13.9 5.1 0.033 13.9 5.1 2.1 1 1 1 2 2 2 0 P-11 zinc finger zf-ANAPC11 PF12861.7 KFM62824.1 - 0.058 13.5 2.1 0.073 13.1 2.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mononeg_RNA_pol PF00946.19 KFM62824.1 - 0.071 10.7 0.0 0.079 10.6 0.0 1.0 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase zf-UDP PF14569.6 KFM62824.1 - 0.11 12.6 3.6 0.15 12.2 3.6 1.4 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 KFM62824.1 - 0.16 11.9 4.5 0.21 11.5 4.5 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFM62824.1 - 0.36 10.6 8.8 0.88 9.4 8.6 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2H2_jaz PF12171.8 KFM62824.1 - 0.72 10.2 7.7 4 7.8 0.3 2.7 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding Auto_anti-p27 PF06677.12 KFM62824.1 - 0.77 10.0 8.4 3.7 7.8 4.6 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_5 PF17121.5 KFM62824.1 - 4.9 7.1 11.0 32 4.5 10.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 KFM62825.1 - 2.8e-17 63.2 0.1 6.3e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Glyco_trans_2_3 PF13632.6 KFM62826.1 - 3.3e-33 115.3 3.8 4e-33 115.0 3.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFM62826.1 - 0.0002 21.3 0.1 0.00024 21.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Hydrolase_4 PF12146.8 KFM62829.1 - 1.9e-69 233.6 0.0 2.2e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM62829.1 - 1.2e-18 67.7 0.0 6.5e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM62829.1 - 1.8e-11 45.1 0.0 3.2e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFM62829.1 - 5.4e-09 36.2 0.0 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 KFM62829.1 - 8.9e-09 35.2 0.0 2e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KFM62829.1 - 1.9e-06 27.0 0.1 2.9e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 KFM62829.1 - 3.9e-06 26.8 0.0 7.1e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.21 KFM62829.1 - 5.2e-06 26.1 0.2 5.5e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KFM62829.1 - 0.0005 19.9 0.0 0.0066 16.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KFM62829.1 - 0.00083 19.1 0.1 0.0048 16.6 0.0 1.9 1 1 1 2 2 2 1 PGAP1-like protein AXE1 PF05448.12 KFM62829.1 - 0.001 17.8 0.2 0.37 9.4 0.0 2.9 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Ser_hydrolase PF06821.13 KFM62829.1 - 0.0011 18.9 0.0 0.067 13.0 0.0 2.6 2 1 0 2 2 2 1 Serine hydrolase LIDHydrolase PF10230.9 KFM62829.1 - 0.0014 18.3 0.1 0.019 14.5 0.1 2.4 2 1 1 3 3 3 1 Lipid-droplet associated hydrolase Esterase PF00756.20 KFM62829.1 - 0.0032 17.2 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KFM62829.1 - 0.0043 16.9 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KFM62829.1 - 0.0062 16.2 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 KFM62829.1 - 0.007 16.5 0.1 0.023 14.8 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain FSH1 PF03959.13 KFM62829.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.13 KFM62829.1 - 0.021 13.4 1.5 1.4 7.4 0.4 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF1350 PF07082.11 KFM62829.1 - 0.039 13.2 0.0 0.093 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1350) BAAT_C PF08840.11 KFM62829.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 KFM62829.1 - 0.081 13.0 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein Hydrolase_4 PF12146.8 KFM62830.1 - 9.2e-73 244.4 0.0 1.1e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM62830.1 - 3.1e-16 59.8 0.0 7.7e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM62830.1 - 6.1e-09 36.8 0.0 7.9e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KFM62830.1 - 7.4e-07 29.1 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 KFM62830.1 - 3.6e-06 26.9 0.0 5.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.21 KFM62830.1 - 0.00012 21.7 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KFM62830.1 - 0.00018 20.5 0.0 0.00027 19.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 KFM62830.1 - 0.00034 20.3 0.0 0.068 12.7 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFM62830.1 - 0.0029 17.4 0.0 0.0084 15.9 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KFM62830.1 - 0.0039 16.8 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 KFM62830.1 - 0.0053 16.6 0.0 0.011 15.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KFM62830.1 - 0.034 13.9 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.13 KFM62830.1 - 0.09 11.3 0.3 1.2 7.6 0.0 2.0 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Acyl_transf_2 PF02273.15 KFM62830.1 - 0.14 11.4 0.0 0.34 10.1 0.1 1.6 2 0 0 2 2 2 0 Acyl transferase DUF2920 PF11144.8 KFM62830.1 - 0.14 11.2 0.0 0.39 9.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Lipocalin PF00061.23 KFM62833.1 - 4.5e-08 33.4 0.5 5.7e-08 33.1 0.5 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFM62833.1 - 1.6e-05 24.8 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.13 KFM62833.1 - 0.00049 20.0 0.0 0.00076 19.4 0.0 1.3 1 0 0 1 1 1 1 Triabin VDE PF07137.11 KFM62833.1 - 0.00084 18.9 0.0 0.0015 18.1 0.0 1.4 1 1 0 1 1 1 1 VDE lipocalin domain HTH_Tnp_Tc3_2 PF01498.18 KFM62834.1 - 2.2e-16 59.9 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62834.1 - 1.3e-13 50.9 0.0 2.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM62835.1 - 0.00051 19.8 0.0 0.00075 19.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease COesterase PF00135.28 KFM62836.1 - 8.6e-23 81.0 0.0 1e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family HTH_Tnp_Tc3_2 PF01498.18 KFM62837.1 - 2.2e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62837.1 - 9.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62838.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62838.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62838.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62838.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62838.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF1397 PF07165.11 KFM62839.1 - 8.2e-05 22.1 14.4 0.00013 21.5 14.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1397) AATF-Che1 PF13339.6 KFM62839.1 - 0.0059 17.3 1.1 0.0093 16.7 1.1 1.3 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor CPG4 PF15481.6 KFM62839.1 - 0.015 15.9 15.8 0.23 12.1 9.4 2.4 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 MetOD1 PF18546.1 KFM62839.1 - 0.016 15.2 2.1 0.029 14.3 2.0 1.5 1 1 0 1 1 1 0 Metanogen output domain 1 IMD PF08397.11 KFM62839.1 - 0.019 14.3 0.8 0.04 13.3 0.8 1.6 1 1 0 1 1 1 0 IRSp53/MIM homology domain DUF1043 PF06295.12 KFM62839.1 - 0.023 14.7 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) IFT57 PF10498.9 KFM62839.1 - 0.037 13.0 0.4 0.048 12.6 0.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Synaptonemal_3 PF15191.6 KFM62839.1 - 0.069 12.9 1.0 0.23 11.2 0.6 2.2 1 1 0 1 1 1 0 Synaptonemal complex central element protein 3 JHD PF17811.1 KFM62839.1 - 0.08 13.5 0.1 0.41 11.2 0.0 1.9 2 0 0 2 2 2 0 Jumonji helical domain KxDL PF10241.9 KFM62839.1 - 0.13 12.5 0.1 0.48 10.7 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF2408 PF10303.9 KFM62839.1 - 0.15 12.6 1.6 0.19 12.3 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) RGM_N PF06535.12 KFM62839.1 - 1.5 9.0 12.3 3.5 7.8 8.6 2.3 1 1 1 2 2 2 0 Repulsive guidance molecule (RGM) N-terminus zf-C2H2 PF00096.26 KFM62840.1 - 9e-18 63.7 38.8 1.8e-05 24.9 4.1 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM62840.1 - 4.3e-17 61.7 37.5 1.4e-06 28.4 5.5 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM62840.1 - 4.6e-16 58.1 35.1 0.0002 21.9 3.3 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.12 KFM62840.1 - 7.1e-09 35.8 17.7 0.00012 22.3 4.8 3.3 2 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFM62840.1 - 4.9e-06 26.2 6.0 4.9e-06 26.2 6.0 4.7 5 1 0 5 5 4 2 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KFM62840.1 - 6.1e-05 23.3 9.9 6.1e-05 23.3 9.9 2.1 1 1 1 2 2 2 1 C2H2-type zinc ribbon GAGA PF09237.11 KFM62840.1 - 0.00012 21.8 8.8 0.19 11.5 0.6 3.2 2 1 1 3 3 3 2 GAGA factor zf-C2H2_6 PF13912.6 KFM62840.1 - 0.00019 21.3 12.9 0.002 18.1 4.3 5.4 5 1 0 5 5 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM62840.1 - 0.0008 19.6 26.6 0.0012 19.1 2.4 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM62840.1 - 0.0069 16.7 24.2 2.3 8.6 2.0 4.0 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFM62840.1 - 0.011 16.2 31.1 0.19 12.2 5.0 4.1 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger BolA PF01722.18 KFM62840.1 - 0.018 15.3 3.9 0.1 12.9 0.4 2.6 1 1 1 2 2 2 0 BolA-like protein zf-met PF12874.7 KFM62840.1 - 0.023 15.1 2.1 0.023 15.1 2.1 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type HypA PF01155.19 KFM62840.1 - 0.084 12.9 10.8 0.2 11.7 1.8 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 KFM62840.1 - 0.16 12.0 25.8 1 9.4 4.2 3.8 1 1 3 4 4 4 0 BED zinc finger zinc_ribbon_15 PF17032.5 KFM62840.1 - 0.18 12.6 13.3 0.14 13.0 3.0 2.4 1 1 2 3 3 3 0 zinc-ribbon family zinc_ribbon_9 PF14369.6 KFM62840.1 - 0.26 11.6 0.2 0.26 11.6 0.2 3.1 4 0 0 4 4 3 0 zinc-ribbon zf_UBZ PF18439.1 KFM62840.1 - 0.45 10.2 0.1 0.45 10.2 0.1 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_12 PF11331.8 KFM62840.1 - 0.57 10.0 10.1 2.6 8.0 0.9 3.2 2 1 1 3 3 3 0 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFM62840.1 - 0.97 9.6 11.8 14 5.9 0.1 3.3 3 1 0 3 3 3 0 Zinc ribbon domain zf-HIT PF04438.16 KFM62840.1 - 1.4 8.8 16.9 0.81 9.6 1.5 4.0 4 0 0 4 4 4 0 HIT zinc finger Yippee-Mis18 PF03226.14 KFM62840.1 - 1.6 9.0 8.8 5.4 7.3 0.1 2.8 3 1 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_9 PF16293.5 KFM62840.1 - 1.9 8.4 11.0 32 4.5 0.1 3.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (1 copy) LIM PF00412.22 KFM62840.1 - 2.4 8.5 12.8 0.13 12.5 4.5 2.7 1 1 2 3 3 3 0 LIM domain FYDLN_acid PF09538.10 KFM62840.1 - 2.6 8.8 7.7 30 5.4 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Zn-C2H2_12 PF18112.1 KFM62840.1 - 6.5 7.3 19.1 3 8.4 0.3 4.7 4 2 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-FPG_IleRS PF06827.14 KFM62840.1 - 6.6 6.7 9.8 15 5.5 0.0 3.5 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zinc_ribbon_4 PF13717.6 KFM62840.1 - 8.8 6.3 15.4 4.4 7.3 3.3 3.5 3 1 0 3 3 2 0 zinc-ribbon domain DUF2417 PF10329.9 KFM62841.1 - 0.97 8.8 6.6 1.1 8.6 6.6 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) LRR_8 PF13855.6 KFM62842.1 - 7.9e-17 60.8 8.7 4.1e-09 36.1 0.1 3.8 3 1 1 4 4 4 3 Leucine rich repeat LRR_5 PF13306.6 KFM62842.1 - 6.9e-09 35.7 3.4 8.4e-07 29.0 0.6 2.3 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM62842.1 - 3.9e-06 27.1 9.4 0.037 14.5 0.4 4.6 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM62842.1 - 0.0012 18.4 7.0 0.0012 18.4 3.1 2.4 1 1 2 3 3 3 1 Leucine-rich repeat LRR_8 PF13855.6 KFM62843.1 - 4.8e-15 55.1 7.7 7.2e-08 32.1 0.8 3.1 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KFM62843.1 - 2.8e-06 27.6 7.6 0.018 15.4 0.1 4.5 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM62843.1 - 0.0047 16.4 5.1 0.038 13.5 0.7 3.3 1 1 2 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 KFM62843.1 - 0.024 15.1 3.1 40 5.3 0.0 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat C5-epim_C PF06662.13 KFM62843.1 - 0.085 12.4 0.1 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus LRR_8 PF13855.6 KFM62844.1 - 2.1e-06 27.4 0.0 0.0029 17.3 0.0 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 KFM62844.1 - 0.0036 17.3 0.1 0.0061 16.5 0.1 1.4 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Integrin_alpha2 PF08441.12 KFM62845.1 - 4.7e-102 342.3 4.3 5.6e-102 342.0 4.3 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFM62845.1 - 9.5e-24 83.2 17.8 8.1e-11 41.9 0.4 4.4 4 0 0 4 4 4 4 FG-GAP repeat VCBS PF13517.6 KFM62845.1 - 1.4e-11 44.8 14.9 1.2e-06 29.0 1.7 3.6 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella LYRIC PF15686.5 KFM62845.1 - 0.3 10.6 0.9 0.49 9.9 0.9 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family FG-GAP_2 PF14312.6 KFM62845.1 - 1.2 9.5 6.3 0.37 11.1 0.4 2.9 3 0 0 3 3 3 0 FG-GAP repeat FG-GAP_2 PF14312.6 KFM62846.1 - 0.00048 20.3 0.2 0.16 12.2 0.0 3.0 3 0 0 3 3 3 2 FG-GAP repeat DdrB PF12747.7 KFM62846.1 - 0.025 14.4 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 DdrB-like protein OSK PF17182.4 KFM62848.1 - 0.088 12.0 0.3 0.089 12.0 0.3 1.0 1 0 0 1 1 1 0 OSK domain Ndc1_Nup PF09531.10 KFM62849.1 - 3.8 6.1 8.9 4.3 5.9 8.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Endostatin PF06482.11 KFM62849.1 - 7.4 5.9 6.3 33 3.8 6.8 1.7 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Senescence_reg PF04520.13 KFM62850.1 - 0.43 11.4 4.9 1.2 9.9 4.9 1.8 1 0 0 1 1 1 0 Senescence regulator Ank_4 PF13637.6 KFM62851.1 - 3.7e-21 75.2 0.5 5.6e-08 33.2 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM62851.1 - 7.2e-21 74.6 2.3 1.5e-09 38.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM62851.1 - 1.5e-13 49.5 1.6 0.091 13.4 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KFM62851.1 - 3.5e-12 46.2 4.9 0.0066 16.8 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFM62851.1 - 1.2e-11 44.6 1.4 5.4e-05 23.4 0.1 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PRA-PH PF01503.17 KFM62851.1 - 0.035 14.6 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase TUDOR PF00567.24 KFM62853.1 - 8.6e-19 67.8 0.0 1.3e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Tudor domain TUDOR PF00567.24 KFM62854.1 - 5.5e-38 129.7 0.0 2.4e-20 72.8 0.0 2.7 2 0 0 2 2 2 2 Tudor domain zf-CCCH PF00642.24 KFM62854.1 - 1.1e-05 25.2 2.6 2.3e-05 24.2 2.6 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM62854.1 - 3.4e-05 23.7 4.3 3.4e-05 23.7 4.3 2.0 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 KFM62854.1 - 0.0012 19.5 4.6 0.003 18.2 0.1 3.1 3 0 0 3 3 3 1 Torus domain zf-CCCH_4 PF18044.1 KFM62854.1 - 0.0021 17.8 4.2 0.0064 16.3 4.2 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger DUF1325 PF07039.11 KFM62854.1 - 0.059 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 SGF29 tudor-like domain Tudor_3 PF18115.1 KFM62854.1 - 0.16 11.8 0.0 0.45 10.4 0.0 1.8 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Ribosomal_L3 PF00297.22 KFM62855.1 - 5.7e-23 81.5 2.0 5.7e-23 81.5 2.0 2.2 3 0 0 3 3 3 1 Ribosomal protein L3 DUF3197 PF11432.8 KFM62855.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Aminotran_1_2 PF00155.21 KFM62856.1 - 1.3e-44 152.9 0.0 1.4e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 KFM62857.1 - 1.1e-14 54.4 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DDE_3 PF13358.6 KFM62858.1 - 3e-09 36.8 0.0 3.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62859.1 - 2.5e-16 59.7 2.2 4.5e-16 58.8 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62859.1 - 9.9e-14 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease KH_1 PF00013.29 KFM62860.1 - 9.5e-191 618.0 59.2 3.4e-16 58.8 0.6 16.0 15 1 0 15 15 15 15 KH domain KH_2 PF07650.17 KFM62860.1 - 1.2e-19 69.9 46.9 0.00015 21.5 0.3 12.9 12 2 0 12 12 12 8 KH domain SLS PF14611.6 KFM62860.1 - 2e-18 67.1 23.5 0.0038 17.1 0.1 9.2 1 1 7 9 9 9 6 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 KFM62860.1 - 1.4e-05 25.1 29.2 3.1 7.9 0.1 11.0 11 1 1 12 12 12 2 NusA-like KH domain TrkA_C PF02080.21 KFM62860.1 - 0.00026 20.8 1.9 46 3.9 0.0 8.1 8 0 0 8 8 8 0 TrkA-C domain RMMBL PF07521.12 KFM62860.1 - 0.0056 16.6 0.4 14 5.7 0.0 5.5 6 0 0 6 6 6 1 Zn-dependent metallo-hydrolase RNA specificity domain KH_4 PF13083.6 KFM62860.1 - 0.013 15.4 19.5 2.1 8.3 0.1 9.2 10 0 0 10 10 10 0 KH domain SurE PF01975.17 KFM62860.1 - 0.031 14.0 0.1 1.3 8.8 0.0 3.5 3 0 0 3 3 3 0 Survival protein SurE Complex1_51K PF01512.17 KFM62860.1 - 0.059 13.3 7.5 1.8 8.5 0.1 5.8 6 1 2 8 8 8 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Sterol-sensing PF12349.8 KFM62861.1 - 0.085 12.7 7.8 0.99 9.2 4.2 2.1 1 1 1 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation COesterase PF00135.28 KFM62862.1 - 3.5e-54 184.6 0.0 4e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DDE_3 PF13358.6 KFM62863.1 - 0.073 12.8 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62864.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62864.1 - 3.6e-13 49.5 0.0 6.3e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62864.1 - 9.5e-09 34.9 0.5 6.8e-07 28.9 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62864.1 - 0.0023 17.7 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62864.1 - 0.037 14.2 3.1 0.088 13.0 0.4 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM62864.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62866.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62866.1 - 1e-13 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM62867.1 - 7.3e-16 58.2 0.1 9.3e-15 54.7 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62867.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DUF4371 PF14291.6 KFM62868.1 - 0.0001 22.1 0.3 0.00075 19.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KFM62868.1 - 0.00013 21.9 0.2 0.00038 20.4 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 KFM62868.1 - 0.0038 17.2 0.1 0.0093 16.0 0.1 1.6 1 0 0 1 1 1 1 BED zinc finger DDE_3 PF13358.6 KFM62869.1 - 3.6e-16 59.2 0.1 5.8e-15 55.3 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62869.1 - 1.5e-15 57.2 6.5 1.5e-15 57.2 6.5 1.8 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM62869.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM62869.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62869.1 - 0.015 15.4 0.1 0.065 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM62869.1 - 0.033 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM62870.1 - 2.2e-14 53.4 0.0 3.6e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62870.1 - 1.5e-10 41.2 1.0 2.4e-10 40.5 1.0 1.4 1 0 0 1 1 1 1 Transposase CBM_14 PF01607.24 KFM62871.1 - 3.4e-09 36.7 5.4 6e-09 35.9 5.4 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain 7tm_3 PF00003.22 KFM62872.1 - 1.4e-13 51.2 17.5 1.8e-13 50.8 17.1 1.3 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2873 PF11395.8 KFM62872.1 - 0.048 13.5 2.1 0.048 13.5 2.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2873) Lipocalin_2 PF08212.12 KFM62874.1 - 0.002 18.1 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain PID PF00640.23 KFM62876.1 - 6e-08 32.8 0.2 1.2e-07 31.8 0.2 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFM62876.1 - 0.00026 21.2 0.2 0.00079 19.6 0.1 1.9 2 0 0 2 2 2 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFM62876.1 - 0.018 14.9 0.1 0.045 13.6 0.1 1.7 1 1 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) DDE_Tnp_4 PF13359.6 KFM62878.1 - 6.6e-39 133.1 0.0 1.1e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease THAP PF05485.12 KFM62878.1 - 2.5e-18 66.8 6.7 6.4e-18 65.5 6.7 1.7 1 0 0 1 1 1 1 THAP domain HTH_Tnp_4 PF13613.6 KFM62878.1 - 1.2e-11 44.1 0.0 2.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KFM62878.1 - 4.1e-07 29.9 0.0 8.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain DEK_C PF08766.11 KFM62879.1 - 2.2e-14 53.1 0.5 2.2e-14 53.1 0.5 1.6 2 0 0 2 2 2 1 DEK C terminal domain NPR3 PF03666.13 KFM62879.1 - 1.2 7.9 6.8 1.3 7.7 6.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.8 KFM62879.1 - 2.3 7.0 10.7 2.6 6.8 10.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eIF3_subunit PF08597.10 KFM62879.1 - 2.8 7.8 19.7 3.1 7.6 19.7 1.3 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Zip PF02535.22 KFM62879.1 - 3.1 6.9 4.2 3 7.0 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 KFM62879.1 - 3.5 5.8 8.5 3.5 5.8 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 KFM62879.1 - 7.3 6.0 9.3 10 5.6 9.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RNase_T PF00929.24 KFM62880.1 - 1.5e-09 38.6 0.0 2.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 KFM62880.1 - 2.2e-05 24.5 0.0 0.083 12.9 0.0 2.2 2 0 0 2 2 2 2 RNase_H superfamily DNA_pol_B_exo1 PF03104.19 KFM62880.1 - 0.0022 17.2 0.1 0.0037 16.4 0.1 1.3 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain PTH2 PF01981.16 KFM62881.1 - 5.1e-40 136.4 0.1 6e-40 136.2 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF1161 PF06649.12 KFM62881.1 - 0.0039 17.4 0.1 0.01 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1161) Phage_TAC_14 PF16462.5 KFM62881.1 - 0.057 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC zf-H2C2_2 PF13465.6 KFM62882.1 - 1.2e-45 152.0 41.5 1.7e-08 34.5 0.6 7.1 7 0 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM62882.1 - 1.3e-32 110.4 47.9 8.2e-07 29.1 0.8 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM62882.1 - 4.8e-23 79.8 45.4 0.00066 20.3 0.8 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM62882.1 - 3e-16 58.9 28.3 0.0026 17.5 0.3 6.7 6 1 0 6 6 6 6 C2H2-type zinc-finger domain zf-met PF12874.7 KFM62882.1 - 1.3e-11 44.5 41.7 0.0049 17.2 1.1 6.4 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM62882.1 - 1.7e-10 40.6 39.7 0.0041 17.1 0.8 6.6 6 1 0 6 6 6 4 C2H2-type zinc finger GAGA PF09237.11 KFM62882.1 - 8.2e-09 35.1 12.8 0.058 13.2 0.0 5.5 1 1 5 6 6 6 3 GAGA factor zf-C2H2_9 PF16293.5 KFM62882.1 - 1.8e-06 27.7 18.3 1.4 8.9 0.4 5.9 2 1 4 6 6 6 4 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 KFM62882.1 - 6.8e-05 23.0 37.7 0.061 13.6 0.3 6.7 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding HNH_5 PF14279.6 KFM62882.1 - 0.00046 20.0 24.7 1.5 8.8 0.3 5.9 4 1 1 5 5 5 1 HNH endonuclease zf-DBF PF07535.12 KFM62882.1 - 0.0014 18.6 19.4 3.8 7.7 0.3 6.1 6 0 0 6 6 6 2 DBF zinc finger zf-Sec23_Sec24 PF04810.15 KFM62882.1 - 0.0016 18.4 13.9 6.5 6.9 0.1 5.8 6 0 0 6 6 6 0 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM62882.1 - 0.0019 18.2 11.2 0.21 11.6 0.1 4.3 1 1 5 6 6 6 2 Adenylate kinase, active site lid zf-RRPl_C4 PF17026.5 KFM62882.1 - 0.0019 18.3 17.8 0.079 13.1 6.0 3.1 1 1 2 3 3 3 3 Putative ribonucleoprotein zinc-finger pf C4 type zf_UBZ PF18439.1 KFM62882.1 - 0.0055 16.3 26.2 0.51 10.0 1.0 6.0 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 KFM62882.1 - 0.0077 16.1 19.4 1.2 9.1 0.2 5.9 6 0 0 6 6 6 1 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.7 KFM62882.1 - 0.011 16.1 38.8 0.39 11.1 1.3 5.8 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) Tox-HNH-HHH PF15637.6 KFM62882.1 - 0.015 15.5 0.5 2.5 8.3 0.0 2.7 1 1 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif C1_1 PF00130.22 KFM62882.1 - 0.027 14.4 31.7 1.3 8.9 0.2 5.9 2 2 4 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFM62882.1 - 0.028 15.2 17.5 1.2 9.9 1.7 3.2 1 1 1 3 3 3 0 zinc-ribbon family zf-C2HC_2 PF13913.6 KFM62882.1 - 0.041 13.8 20.2 4.6 7.3 0.1 5.7 6 0 0 6 6 5 0 zinc-finger of a C2HC-type DUF2757 PF10955.8 KFM62882.1 - 0.08 13.2 19.8 3.1 8.1 0.1 5.8 5 1 1 6 6 6 0 Protein of unknown function (DUF2757) zf-C2H2_11 PF16622.5 KFM62882.1 - 0.16 11.7 0.1 0.16 11.7 0.1 6.1 6 0 0 6 6 6 0 zinc-finger C2H2-type FYVE PF01363.21 KFM62882.1 - 0.2 11.8 29.2 3.7 7.8 9.6 4.2 1 1 3 4 4 4 0 FYVE zinc finger zf-Dof PF02701.15 KFM62882.1 - 0.59 10.3 12.3 29 4.9 0.0 5.0 1 1 4 5 5 5 0 Dof domain, zinc finger zf-MYST PF17772.1 KFM62882.1 - 0.84 9.3 22.5 12 5.6 0.1 5.9 3 1 3 6 6 6 0 MYST family zinc finger domain XPA_N PF01286.18 KFM62882.1 - 1.6 8.8 25.0 5.9 7.0 0.3 5.9 6 0 0 6 6 6 0 XPA protein N-terminal TRAF6_Z2 PF18048.1 KFM62882.1 - 2.8 8.1 35.5 1.1 9.4 0.6 6.0 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 zf_PR_Knuckle PF18445.1 KFM62882.1 - 4.4 7.2 7.4 54 3.7 0.0 4.5 5 0 0 5 5 5 0 PR zinc knuckle motif Cu2_monooxygen PF01082.20 KFM62884.1 - 1.2e-20 74.1 0.1 1.4e-20 73.8 0.1 1.1 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 KFM62884.1 - 0.026 14.0 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Frataxin_Cyay PF01491.16 KFM62886.1 - 5.4e-36 123.0 0.3 7.6e-36 122.5 0.3 1.2 1 0 0 1 1 1 1 Frataxin-like domain LRR_8 PF13855.6 KFM62887.1 - 2.2e-26 91.4 27.8 2.5e-09 36.7 2.9 5.0 3 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KFM62887.1 - 1.9e-25 88.5 29.5 8.8e-07 29.2 3.2 6.2 4 1 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM62887.1 - 2.1e-09 36.6 27.4 0.77 10.5 2.3 9.7 9 1 0 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.6 KFM62887.1 - 0.00036 20.1 9.0 0.022 14.3 0.3 3.1 1 1 2 3 3 3 3 Leucine-rich repeat DUF2129 PF09902.9 KFM62887.1 - 0.1 12.7 0.0 11 6.2 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) LRR_6 PF13516.6 KFM62887.1 - 5.6 7.3 25.8 4.6 7.6 0.3 8.0 8 0 0 8 8 8 0 Leucine Rich repeat Y_phosphatase PF00102.27 KFM62890.1 - 4.4e-140 465.0 3.2 3.9e-81 272.1 1.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFM62890.1 - 4.9e-51 171.0 3.6 1.2e-12 48.0 0.0 6.9 5 2 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM62890.1 - 1.4e-09 38.3 0.0 0.16 12.6 0.0 5.0 4 0 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain DSPc PF00782.20 KFM62890.1 - 2.5e-08 33.8 0.9 5.2e-05 23.1 0.0 3.0 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain PTP_tm PF18861.1 KFM62890.1 - 0.0018 18.3 0.2 0.0086 16.1 0.1 2.2 2 0 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4006 PF13179.6 KFM62890.1 - 0.0065 16.4 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF4006) Y_phosphatase3 PF13350.6 KFM62890.1 - 0.0083 16.1 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family ABC_membrane PF00664.23 KFM62891.1 - 0.00051 19.8 0.9 0.00073 19.3 0.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Cation_ATPase_C PF00689.21 KFM62891.1 - 0.007 16.1 0.1 0.0093 15.7 0.1 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Aph-1 PF06105.12 KFM62891.1 - 0.043 13.2 1.5 0.068 12.6 1.5 1.3 1 0 0 1 1 1 0 Aph-1 protein ABC_tran PF00005.27 KFM62892.1 - 1.4e-36 126.0 0.9 6.2e-20 72.1 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 KFM62892.1 - 2e-34 119.5 21.0 9.6e-22 77.9 11.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_15 PF13175.6 KFM62892.1 - 0.00079 19.2 4.6 0.52 10.0 2.6 2.3 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KFM62892.1 - 0.0018 18.4 0.8 0.012 15.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFM62892.1 - 0.0047 17.0 0.0 0.018 15.1 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFM62892.1 - 0.048 14.1 0.7 0.17 12.2 0.1 2.1 2 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 KFM62892.1 - 0.087 12.6 0.0 1.5 8.6 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain TSP_1 PF00090.19 KFM62893.1 - 1.1e-13 51.2 11.1 3.1e-13 49.7 11.1 1.8 1 0 0 1 1 1 1 Thrombospondin type 1 domain APA3_viroporin PF11289.8 KFM62894.1 - 0.00012 21.7 2.5 0.00012 21.7 2.5 1.2 1 1 0 1 1 1 1 Coronavirus accessory protein 3a HTH_Tnp_Tc3_2 PF01498.18 KFM62895.1 - 6.4e-11 42.3 2.1 9.1e-10 38.7 0.4 2.2 2 0 0 2 2 2 1 Transposase HTH_7 PF02796.15 KFM62895.1 - 1.1e-08 35.0 0.3 1e-05 25.5 0.1 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM62895.1 - 4.1e-08 32.8 4.1 8.9e-07 28.5 0.0 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62895.1 - 2.7e-07 30.6 2.2 3e-05 24.1 0.1 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM62895.1 - 3.1e-07 30.9 1.1 5.2e-07 30.2 1.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 KFM62895.1 - 3.5e-06 26.8 0.6 0.00017 21.4 0.0 2.5 1 1 1 2 2 2 1 MarR family HTH_29 PF13551.6 KFM62895.1 - 1.1e-05 25.4 0.7 4.6e-05 23.3 0.1 2.1 2 1 0 2 2 2 1 Winged helix-turn helix HTH_20 PF12840.7 KFM62895.1 - 0.00051 20.1 0.0 0.096 12.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM62895.1 - 0.00078 19.4 0.4 0.0058 16.6 0.0 2.2 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM62895.1 - 0.0053 16.4 0.1 0.018 14.7 0.0 1.9 2 1 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_30 PF13556.6 KFM62895.1 - 0.0061 16.3 2.0 0.26 11.1 0.0 3.0 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain TrmB PF01978.19 KFM62895.1 - 0.0075 16.1 0.1 0.61 10.0 0.0 2.3 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB TnsD PF15978.5 KFM62895.1 - 0.0099 14.9 0.9 0.012 14.7 0.9 1.1 1 0 0 1 1 1 1 Tn7-like transposition protein D Sigma70_r4 PF04545.16 KFM62895.1 - 0.016 14.8 0.3 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 CENP-B_N PF04218.13 KFM62895.1 - 0.022 14.4 0.3 0.057 13.1 0.1 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain PAX PF00292.18 KFM62895.1 - 0.033 14.1 0.0 0.038 13.9 0.0 1.2 1 1 0 1 1 1 0 'Paired box' domain HTH_Tnp_IS630 PF01710.16 KFM62895.1 - 0.04 14.0 0.3 0.15 12.1 0.1 2.0 1 1 2 3 3 3 0 Transposase HTH_26 PF13443.6 KFM62895.1 - 0.042 14.3 0.5 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 KFM62895.1 - 0.046 13.1 3.9 0.56 9.7 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.19 KFM62895.1 - 0.046 13.3 0.1 0.68 9.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_22 PF13309.6 KFM62895.1 - 0.047 13.8 0.3 7.2 6.8 0.0 2.8 2 2 0 2 2 2 0 HTH domain HTH_17 PF12728.7 KFM62895.1 - 0.052 13.7 0.0 3 8.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 KFM62895.1 - 0.053 13.9 0.1 0.27 11.6 0.0 2.0 1 1 1 2 2 2 0 Transcriptional regulator MarR PF01047.22 KFM62895.1 - 0.08 12.9 0.7 0.33 10.9 0.0 2.2 2 2 0 2 2 2 0 MarR family DUF603 PF04645.12 KFM62895.1 - 0.15 11.8 0.7 0.47 10.1 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF603 HTH_3 PF01381.22 KFM62895.1 - 0.21 11.7 2.7 23 5.1 0.2 3.0 2 1 1 3 3 3 0 Helix-turn-helix HTH_38 PF13936.6 KFM62895.1 - 0.33 10.8 3.6 1 9.2 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain C2 PF00168.30 KFM62896.1 - 1.4e-07 31.7 0.0 3.3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain CHDCT2 PF08074.11 KFM62896.1 - 0.021 15.0 0.9 0.54 10.4 0.0 2.9 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain FapA PF03961.13 KFM62896.1 - 0.055 12.1 13.3 0.053 12.1 0.5 3.2 3 0 0 3 3 3 0 Flagellar Assembly Protein A RhoGAP PF00620.27 KFM62897.1 - 6.1e-48 162.5 0.5 1.3e-47 161.5 0.5 1.5 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 KFM62897.1 - 3.4e-18 65.4 9.2 7.3e-08 32.4 1.1 3.4 2 1 1 3 3 3 3 WW domain PH PF00169.29 KFM62897.1 - 1.1e-10 41.9 2.1 1.8e-09 38.1 0.0 3.3 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 KFM62897.1 - 2.6e-08 34.2 0.0 8.4e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_1 PF00018.28 KFM62897.1 - 0.00012 21.6 0.3 0.00029 20.4 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM62897.1 - 0.00013 21.7 0.2 0.0004 20.2 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain MHB PF16525.5 KFM62897.1 - 0.052 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Haemophore, haem-binding Glyco_hyd_101C PF17451.2 KFM62897.1 - 0.45 10.8 5.0 9.3 6.6 0.1 3.0 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Lysyl_oxidase PF01186.17 KFM62898.1 - 3.7e-96 320.6 1.6 5.4e-96 320.1 1.6 1.2 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.18 KFM62898.1 - 1.4e-51 173.1 9.2 7.7e-28 96.9 2.5 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFM62898.1 - 1.6e-10 41.4 4.4 0.00016 22.2 0.9 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFM62898.1 - 0.0022 18.5 0.2 0.37 11.3 0.0 2.8 2 0 0 2 2 2 1 Hepsin, SRCR domain CSD PF00313.22 KFM62898.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain VPS9 PF02204.18 KFM62899.1 - 7.8e-18 64.6 0.2 1.9e-17 63.4 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PIN_8 PF18476.1 KFM62899.1 - 0.066 13.1 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 PIN like domain Lin-8 PF03353.15 KFM62902.1 - 0.082 12.5 0.4 0.1 12.2 0.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DDE_3 PF13358.6 KFM62904.1 - 5.3e-16 58.7 0.1 6e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM62904.1 - 8e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM62904.1 - 0.00071 19.3 0.0 0.029 14.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62904.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62904.1 - 0.0016 18.5 0.0 0.0061 16.7 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM62904.1 - 0.0058 16.6 1.1 0.014 15.4 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 KFM62904.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KFM62905.1 - 5.5e-16 58.6 3.5 6.2e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62905.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62905.1 - 3.1e-07 30.1 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62905.1 - 0.0028 17.4 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62905.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM62906.1 - 0.092 12.5 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease SOG2 PF10428.9 KFM62907.1 - 6.7 5.8 10.7 8.1 5.5 10.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Homeodomain PF00046.29 KFM62909.1 - 1.1e-20 73.1 3.6 4.4e-20 71.3 4.1 1.8 2 0 0 2 2 2 1 Homeodomain Mei5 PF10376.9 KFM62909.1 - 0.031 14.1 0.3 0.061 13.2 0.3 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein Homeobox_KN PF05920.11 KFM62909.1 - 0.039 13.9 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 KFM62911.1 - 1.7e-20 72.6 3.2 3.8e-20 71.5 3.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM62911.1 - 0.0099 15.8 1.2 0.022 14.7 0.5 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 KFM62911.1 - 0.11 12.0 0.2 0.26 10.8 0.2 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Fer4 PF00037.27 KFM62912.1 - 3.3e-14 52.0 17.5 1.5e-08 34.1 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KFM62912.1 - 2.3e-13 50.5 10.5 3.9e-13 49.8 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFM62912.1 - 1.3e-10 42.0 6.5 5e-05 24.2 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KFM62912.1 - 1.5e-09 37.9 31.8 6.2e-06 26.3 12.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFM62912.1 - 6.3e-09 35.8 21.6 1.5e-06 28.2 12.6 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFM62912.1 - 1.1e-08 35.1 10.5 1.8e-08 34.4 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFM62912.1 - 2.4e-07 30.5 17.8 0.00033 20.6 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KFM62912.1 - 8.6e-07 28.7 12.1 0.0023 17.9 2.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KFM62912.1 - 1.2e-06 28.8 20.2 0.00028 21.3 11.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KFM62912.1 - 4.3e-06 26.8 11.1 0.00025 21.3 1.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KFM62912.1 - 0.00056 20.4 12.2 0.054 14.0 13.0 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KFM62912.1 - 0.01 16.4 14.6 0.55 10.8 2.6 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 KFM62912.1 - 0.013 15.7 6.0 0.28 11.5 0.2 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KFM62912.1 - 0.027 14.7 8.7 0.87 9.8 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KFM62912.1 - 0.069 13.3 5.6 0.4 10.9 0.6 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S AfsA PF03756.13 KFM62912.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain Fer4_3 PF12798.7 KFM62912.1 - 0.14 13.2 16.3 0.29 12.2 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain EPF PF17181.4 KFM62912.1 - 0.22 11.5 4.3 0.29 11.2 0.5 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_22 PF17179.4 KFM62912.1 - 0.37 11.7 11.7 3 8.7 2.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Lar_restr_allev PF14354.6 KFM62912.1 - 2.5 8.5 7.9 3.8 8.0 0.7 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar HTH_Tnp_Tc3_2 PF01498.18 KFM62913.1 - 8.5e-16 58.0 6.5 1.5e-15 57.2 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62913.1 - 1.2e-15 57.6 0.1 1.3e-14 54.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM62913.1 - 0.00034 20.3 0.1 0.019 14.7 0.0 3.3 4 0 0 4 4 4 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62913.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.8 3 1 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM62913.1 - 0.011 15.7 1.5 0.021 14.8 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 KFM62913.1 - 0.016 15.4 0.1 0.061 13.5 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 KFM62913.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Promethin PF16015.5 KFM62915.1 - 0.009 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Promethin SID-1_RNA_chan PF13965.6 KFM62915.1 - 0.011 14.2 1.2 0.013 13.9 1.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 KFM62915.1 - 0.05 12.8 0.2 0.067 12.4 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sugar_tr PF00083.24 KFM62915.1 - 0.084 11.7 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter Presenilin PF01080.17 KFM62915.1 - 0.11 11.3 0.5 0.14 10.9 0.5 1.2 1 0 0 1 1 1 0 Presenilin TMIE PF16038.5 KFM62915.1 - 0.12 12.2 1.3 0.17 11.8 0.2 1.8 1 1 1 2 2 2 0 TMIE protein HCO3_cotransp PF00955.21 KFM62915.1 - 0.19 10.5 0.0 0.23 10.2 0.0 1.0 1 0 0 1 1 1 0 HCO3- transporter family SieB PF14163.6 KFM62915.1 - 0.21 11.1 0.2 0.41 10.1 0.2 1.6 1 1 0 1 1 1 0 Super-infection exclusion protein B Connexin PF00029.19 KFM62915.1 - 1 9.1 6.4 6.3 6.5 6.4 1.9 1 1 0 1 1 1 0 Connexin LRR19-TM PF15176.6 KFM62915.1 - 1.3 9.1 6.3 0.15 12.1 1.3 2.0 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain HTH_Tnp_Tc3_2 PF01498.18 KFM62916.1 - 2.6e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62916.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62916.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62916.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62916.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF4371 PF14291.6 KFM62917.1 - 0.00036 20.2 0.1 0.00074 19.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Chitin_bind_4 PF00379.23 KFM62918.1 - 7.8e-11 42.3 11.3 7.8e-11 42.3 11.3 1.8 2 0 0 2 2 2 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM62919.1 - 8.7e-10 39.0 9.0 4.3e-09 36.8 9.0 2.3 1 0 0 1 1 1 1 Insect cuticle protein HTH_Tnp_Tc3_1 PF11427.8 KFM62920.1 - 5e-05 23.1 0.0 6.9e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Tc3 transposase HOCHOB PF17943.1 KFM62920.1 - 0.043 14.5 0.0 0.05 14.3 0.0 1.1 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox DUF2774 PF11242.8 KFM62920.1 - 0.055 13.7 0.0 0.069 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Med20 PF08612.11 KFM62920.1 - 0.059 12.7 0.1 0.059 12.7 0.1 1.0 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex HTH_38 PF13936.6 KFM62920.1 - 0.062 13.1 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4371 PF14291.6 KFM62921.1 - 1.7e-09 37.7 4.0 2.4e-09 37.2 1.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4371) zf-BED PF02892.15 KFM62921.1 - 8e-05 22.6 0.1 0.00032 20.7 0.1 2.1 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_12 PF18658.1 KFM62921.1 - 0.0014 18.2 0.5 0.036 13.6 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger C2H2-type DUF659 PF04937.15 KFM62921.1 - 0.027 14.3 0.2 0.066 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Thioredoxin PF00085.20 KFM62922.1 - 1.1e-11 44.6 0.2 0.00016 21.6 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KFM62922.1 - 1.3e-10 41.5 0.2 2.7e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 KFM62922.1 - 4.7e-10 39.4 0.1 9e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KFM62922.1 - 0.00077 19.9 3.7 0.73 10.3 0.1 3.1 2 2 0 2 2 2 2 Thioredoxin-like domain DIM1 PF02966.16 KFM62922.1 - 0.027 14.3 0.8 0.6 9.9 0.1 2.7 1 1 2 3 3 3 0 Mitosis protein DIM1 RBFA PF02033.18 KFM62922.1 - 0.079 13.4 0.0 5.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Ribosome-binding factor A Thioredoxin_8 PF13905.6 KFM62922.1 - 0.098 13.0 0.3 6.1 7.2 0.0 3.4 3 1 0 3 3 3 0 Thioredoxin-like TrbC_Ftype PF09673.10 KFM62922.1 - 0.1 12.6 0.0 1.5 8.9 0.0 2.5 2 1 1 3 3 3 0 Type-F conjugative transfer system pilin assembly protein DUF1525 PF07511.11 KFM62922.1 - 0.11 12.7 0.0 18 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) TraF PF13728.6 KFM62922.1 - 0.12 12.2 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Arginase PF00491.21 KFM62923.1 - 1.1e-05 25.0 0.0 1.1e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family Mis12 PF05859.12 KFM62924.1 - 1.6e-15 57.4 3.7 1.6e-15 57.4 3.7 1.9 2 0 0 2 2 2 1 Mis12 protein Spc7 PF08317.11 KFM62924.1 - 0.012 14.5 11.0 0.024 13.5 11.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KFM62924.1 - 0.015 15.2 7.2 0.026 14.3 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Gluconate_2-dh3 PF13618.6 KFM62924.1 - 0.017 15.3 0.8 0.026 14.7 0.8 1.4 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 MnmE_helical PF12631.7 KFM62924.1 - 0.019 15.1 6.8 0.046 13.9 6.1 1.8 1 1 1 2 2 2 0 MnmE helical domain S4 PF01479.25 KFM62924.1 - 0.05 13.3 0.1 0.14 11.9 0.1 1.8 1 1 0 1 1 1 0 S4 domain TBCA PF02970.16 KFM62924.1 - 0.062 13.6 9.7 0.51 10.7 0.0 3.3 1 1 2 3 3 3 0 Tubulin binding cofactor A DUF3450 PF11932.8 KFM62924.1 - 0.095 12.0 8.4 0.059 12.7 6.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2959 PF11172.8 KFM62924.1 - 0.17 12.0 6.2 0.099 12.8 1.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) DUF2443 PF10398.9 KFM62924.1 - 0.35 10.9 7.4 0.11 12.6 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) Focal_AT PF03623.13 KFM62924.1 - 0.38 10.7 7.6 0.049 13.6 2.0 2.0 1 1 1 2 2 2 0 Focal adhesion targeting region AAA_15 PF13175.6 KFM62924.1 - 0.43 10.2 10.9 0.66 9.6 10.9 1.4 1 1 0 1 1 1 0 AAA ATPase domain Spc29 PF17082.5 KFM62924.1 - 0.48 10.2 7.5 0.46 10.3 5.9 1.7 1 1 0 2 2 2 0 Spindle Pole Component 29 DUF1664 PF07889.12 KFM62924.1 - 0.96 9.5 7.0 6.5 6.8 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_A3 PF02160.15 KFM62924.1 - 0.97 8.9 9.6 5.3 6.5 9.6 2.0 1 1 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) NUDIX PF00293.28 KFM62925.1 - 1.6e-05 24.9 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DDE_3 PF13358.6 KFM62927.1 - 8.2e-05 22.4 0.0 0.00017 21.3 0.1 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease FTCD_N PF07837.12 KFM62928.1 - 1e-69 233.8 0.0 1.7e-69 233.1 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 KFM62928.1 - 7.8e-67 223.8 0.0 1.3e-66 223.1 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_C PF04961.12 KFM62928.1 - 4.4e-65 218.9 1.2 7.1e-65 218.2 1.2 1.3 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase PHD PF00628.29 KFM62929.1 - 9e-07 28.7 11.0 0.00016 21.4 8.0 2.4 1 1 1 2 2 2 2 PHD-finger Trm112p PF03966.16 KFM62929.1 - 0.0077 16.8 1.4 0.0077 16.8 1.4 2.8 2 1 0 2 2 2 1 Trm112p-like protein Zn_ribbon_17 PF17120.5 KFM62929.1 - 0.047 13.3 8.0 0.13 11.9 8.0 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 KFM62929.1 - 0.085 13.0 11.2 0.16 12.1 5.9 2.6 1 1 2 3 3 3 0 KIAA1045 RING finger PHD_2 PF13831.6 KFM62929.1 - 0.18 11.4 12.0 0.38 10.4 5.1 2.4 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KFM62929.1 - 0.39 10.6 13.5 0.22 11.4 8.2 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.6 KFM62929.1 - 0.9 9.6 9.7 1.4 8.9 9.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFM62929.1 - 0.96 9.8 9.8 2.2 8.7 9.1 1.9 1 1 1 2 2 2 0 Ring finger domain ADK_lid PF05191.14 KFM62929.1 - 2.9 8.0 5.9 0.44 10.6 1.8 1.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid Bromodomain PF00439.25 KFM62930.1 - 3.7e-08 33.3 0.1 9.7e-08 32.0 0.1 1.8 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 KFM62930.1 - 9.9e-07 29.1 0.1 9.9e-07 29.1 0.1 3.3 2 2 0 2 2 2 1 PWWP domain zf-MYND PF01753.18 KFM62930.1 - 0.01 15.9 21.3 0.01 15.9 21.3 2.7 2 0 0 2 2 2 0 MYND finger BtrH_N PF14399.6 KFM62930.1 - 0.068 13.4 0.1 3.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Butirosin biosynthesis protein H, N-terminal DUF3416 PF11896.8 KFM62930.1 - 1.9 8.8 8.1 0.79 10.0 5.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) RVT_1 PF00078.27 KFM62934.1 - 1e-06 28.5 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KFM62935.1 - 6.2e-10 38.9 0.8 7.2e-10 38.7 0.8 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type tRNA-synt_2b PF00587.25 KFM62936.1 - 1.9e-06 28.0 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2b PF00587.25 KFM62937.1 - 2.3e-10 40.7 0.0 2.5e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) GCP_C_terminal PF04130.13 KFM62939.1 - 6.9e-54 183.4 0.3 7.6e-54 183.3 0.3 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Acetyltransf_1 PF00583.25 KFM62940.1 - 0.0055 16.9 0.0 0.0076 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM62940.1 - 0.028 14.8 0.1 0.055 13.9 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CIA30 PF08547.12 KFM62941.1 - 1.6e-35 122.5 0.0 2.1e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 KFM62941.1 - 0.073 12.9 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate binding domain (family 11) PAN_1 PF00024.26 KFM62942.1 - 6.7e-26 90.1 30.5 2.1e-16 59.6 1.1 4.3 4 0 0 4 4 4 3 PAN domain PAN_4 PF14295.6 KFM62942.1 - 0.0094 15.8 16.5 0.016 15.1 1.0 4.5 3 1 1 4 4 4 2 PAN domain Kelch_6 PF13964.6 KFM62943.1 - 0.05 13.9 0.1 0.075 13.4 0.1 1.3 1 0 0 1 1 1 0 Kelch motif CDI PF02234.19 KFM62944.1 - 3.2e-16 59.2 0.3 6.6e-16 58.2 0.3 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor HIT PF01230.23 KFM62946.1 - 3.7e-30 104.5 0.0 5.8e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFM62946.1 - 2.9e-26 92.2 0.1 3.9e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HTH_Tnp_Tc3_2 PF01498.18 KFM62947.1 - 5.2e-10 39.4 0.2 1.1e-09 38.5 0.2 1.5 1 0 0 1 1 1 1 Transposase MutS_V PF00488.21 KFM62949.1 - 4.3e-42 144.3 0.1 7.9e-42 143.4 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFM62949.1 - 7.4e-22 78.5 0.3 1.9e-21 77.2 0.1 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KFM62949.1 - 6.8e-10 39.2 0.0 2.8e-09 37.2 0.0 2.2 1 0 0 1 1 1 1 MutS family domain IV DAP3 PF10236.9 KFM62949.1 - 0.022 13.9 0.0 0.052 12.7 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TFIID-18kDa PF02269.16 KFM62949.1 - 0.039 14.0 0.9 0.18 11.8 0.1 2.5 3 0 0 3 3 3 0 Transcription initiation factor IID, 18kD subunit AAA_14 PF13173.6 KFM62949.1 - 0.044 13.8 0.3 0.29 11.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KFM62949.1 - 0.053 13.3 1.9 0.14 12.0 0.1 2.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM62949.1 - 0.15 11.5 0.6 1.6 8.1 0.0 2.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain F-box-like_2 PF13013.6 KFM62953.1 - 0.02 14.9 0.4 0.058 13.4 0.1 2.0 2 0 0 2 2 2 0 F-box-like domain UBX PF00789.20 KFM62954.1 - 0.08 13.1 0.2 0.39 11.0 0.2 2.2 1 0 0 1 1 1 0 UBX domain Cas_CXXC_CXXC PF09706.10 KFM62954.1 - 0.15 12.3 0.6 1.2 9.4 0.1 2.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) RPE65 PF03055.15 KFM62955.1 - 0.037 13.2 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein UPF0556 PF10572.9 KFM62956.1 - 0.017 14.6 0.2 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0556 PAX PF00292.18 KFM62957.1 - 9.5e-74 245.3 0.4 1.5e-73 244.6 0.4 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFM62957.1 - 8.2e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62957.1 - 0.0001 22.8 0.2 0.11 13.1 0.0 2.7 2 1 1 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 KFM62957.1 - 0.049 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS1 PF12759.7 KFM62957.1 - 0.11 12.2 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 InsA C-terminal domain DUF4371 PF14291.6 KFM62958.1 - 1.4e-26 93.6 0.0 2.5e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM62958.1 - 2.2e-10 40.2 0.1 5.3e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KFM62958.1 - 0.0031 17.4 0.1 0.0079 16.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RSS_P20 PF11757.8 KFM62958.1 - 0.013 15.9 0.7 0.11 12.9 0.1 2.6 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM62959.1 - 2.1e-16 59.9 2.2 5.6e-16 58.6 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62959.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62959.1 - 2.2e-07 30.5 0.8 9.3e-07 28.5 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 KFM62959.1 - 0.018 15.1 0.4 0.057 13.6 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain PRKCSH_1 PF13015.6 KFM62960.1 - 2.2e-12 46.9 0.1 3.7e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KFM62960.1 - 1.7e-10 41.8 3.3 3.5e-10 40.7 3.3 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Brix PF04427.18 KFM62962.1 - 5.7e-33 114.6 4.4 7e-33 114.4 4.4 1.1 1 0 0 1 1 1 1 Brix domain CMS1 PF14617.6 KFM62962.1 - 0.056 12.8 0.3 0.078 12.3 0.3 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Amino_oxidase PF01593.24 KFM62963.1 - 1.3e-14 54.4 0.0 6.1e-08 32.4 0.0 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM62963.1 - 0.00048 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain RRM_1 PF00076.22 KFM62965.1 - 3.9e-47 157.9 0.1 8.4e-19 67.2 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM62965.1 - 5.7e-10 38.9 0.0 0.03 13.9 0.0 3.1 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM62965.1 - 0.00011 21.9 0.0 0.083 12.8 0.0 2.9 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KFM62965.1 - 0.0014 18.6 0.2 2.6 8.1 0.0 3.3 2 1 1 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KFM62965.1 - 0.024 14.7 0.0 14 5.9 0.0 3.1 3 1 0 3 3 3 0 RNA recognition motif PKD_channel PF08016.12 KFM62966.1 - 1.8e-142 475.0 17.2 1.8e-142 475.0 17.2 1.8 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KFM62966.1 - 1.3e-24 86.8 25.6 1.3e-24 86.8 25.6 2.1 2 0 0 2 2 2 1 Ion transport protein EF-hand_1 PF00036.32 KFM62966.1 - 9e-09 34.3 2.5 0.0017 17.8 1.1 2.8 2 0 0 2 2 2 2 EF hand Fer4_24 PF18109.1 KFM62966.1 - 6.1e-08 32.8 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin I 4Fe-4S cluster domain EF-hand_6 PF13405.6 KFM62966.1 - 7.8e-08 31.7 1.6 0.0043 16.9 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFM62966.1 - 6.4e-06 26.5 1.4 6.4e-06 26.5 1.4 2.5 2 0 0 2 2 2 1 EF-hand domain pair Gal4_dimer PF03902.13 KFM62966.1 - 0.13 12.4 0.9 0.51 10.5 0.1 2.5 2 0 0 2 2 2 0 Gal4-like dimerisation domain DUF932 PF06067.11 KFM62966.1 - 6.6 6.4 6.9 0.99 9.1 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF932) Myosin_head PF00063.21 KFM62967.1 - 8.1e-221 734.9 4.2 1.1e-220 734.4 4.2 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFM62967.1 - 1.7e-30 106.1 0.1 4.9e-30 104.6 0.1 1.8 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 KFM62967.1 - 9.5e-05 21.9 12.5 0.0097 15.6 1.8 3.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif AAA_22 PF13401.6 KFM62967.1 - 0.0016 18.7 0.0 0.0058 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM62967.1 - 0.032 13.5 0.0 0.068 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KFM62967.1 - 0.034 14.5 0.0 0.085 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KFM62967.1 - 0.14 12.7 0.0 0.54 10.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain Tim17 PF02466.19 KFM62968.1 - 1.6e-26 92.8 9.0 2e-26 92.5 9.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 KFM62968.1 - 2.6 8.5 11.0 9.1 6.7 2.3 2.4 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DcpS PF05652.12 KFM62969.1 - 3.3e-12 47.2 0.0 4.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KFM62970.1 - 0.024 15.1 0.0 0.027 14.9 0.0 1.2 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding HTH_Tnp_Tc3_2 PF01498.18 KFM62973.1 - 2.5e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM62973.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4817 PF16087.5 KFM62974.1 - 1.3e-07 31.3 0.0 3.7e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_Tnp_Tc3_2 PF01498.18 KFM62974.1 - 8.4e-07 29.2 0.1 1.6e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM62974.1 - 0.005 17.4 0.6 0.011 16.3 0.6 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 KFM62974.1 - 0.015 14.8 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 KFM62974.1 - 0.02 14.3 0.1 0.041 13.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 C2 PF00168.30 KFM62975.1 - 1.8e-07 31.4 0.0 2.2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 C2 domain OrfB_Zn_ribbon PF07282.11 KFM62976.1 - 0.1 12.5 3.7 0.12 12.3 3.7 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2188 PF09954.9 KFM62976.1 - 0.11 12.6 0.0 0.23 11.7 0.0 1.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) ARS2 PF04959.13 KFM62978.1 - 6.7e-60 202.8 3.4 6.7e-60 202.8 3.4 2.9 3 0 0 3 3 3 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 KFM62978.1 - 1.7e-40 137.6 5.9 1.7e-40 137.6 5.9 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) RRM_1 PF00076.22 KFM62978.1 - 0.00025 20.8 0.0 0.00099 18.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.9 KFM62978.1 - 0.15 10.6 16.5 0.25 9.8 16.5 1.3 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 KFM62980.1 - 3.1e-31 108.6 39.1 5.1e-16 58.5 16.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EVC2_like PF12297.8 KFM62980.1 - 0.11 11.2 0.5 0.31 9.7 0.0 1.8 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Synapsin PF02078.16 KFM62984.1 - 6.1e-47 158.1 0.0 7.3e-47 157.8 0.0 1.1 1 0 0 1 1 1 1 Synapsin, N-terminal domain TIMP PF00965.17 KFM62985.1 - 1.6e-33 116.0 6.3 2.4e-33 115.5 6.3 1.2 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 KFM62985.1 - 8.7e-09 35.2 0.1 1.6e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Synapsin_C PF02750.14 KFM62986.1 - 1.3e-55 188.1 0.3 1.6e-55 187.8 0.3 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Totivirus_coat PF05518.11 KFM62986.1 - 1 7.3 12.9 1.5 6.7 12.9 1.2 1 0 0 1 1 1 0 Totivirus coat protein adh_short PF00106.25 KFM62987.1 - 2.9e-16 59.5 0.0 3.1e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM62987.1 - 1.8e-08 34.2 0.0 1.9e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2316 PF10078.9 KFM62987.1 - 0.074 13.3 0.0 0.089 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) RT_RNaseH_2 PF17919.1 KFM62988.1 - 7.5e-31 106.1 0.0 2e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM62988.1 - 5.5e-28 98.0 1.5 8.9e-28 97.3 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM62988.1 - 6.3e-28 97.1 0.0 1.8e-27 95.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM62988.1 - 6.5e-20 71.0 0.2 3.4e-19 68.7 0.2 2.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM62988.1 - 9.2e-18 64.6 0.0 2e-15 57.0 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KFM62988.1 - 3.3e-09 37.2 0.0 1.1e-08 35.5 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM62988.1 - 1.7e-05 25.3 0.0 4.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM62988.1 - 2e-05 24.8 0.0 5.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KFM62988.1 - 5e-05 23.4 1.0 0.00015 21.9 1.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KFM62988.1 - 8.6e-05 22.3 0.0 0.00026 20.7 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 KFM62988.1 - 0.0032 17.5 20.2 0.0099 15.9 3.3 3.2 3 0 0 3 3 3 2 Zinc knuckle RVT_3 PF13456.6 KFM62988.1 - 0.0032 17.3 0.1 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like Asp_protease PF09668.10 KFM62988.1 - 0.0034 17.2 0.1 0.0087 15.9 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease BH4 PF02180.17 KFM62988.1 - 0.062 13.1 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Bcl-2 homology region 4 zf-CCHC_4 PF14392.6 KFM62988.1 - 0.08 12.7 8.8 0.23 11.2 1.2 2.8 2 0 0 2 2 2 0 Zinc knuckle TFIIA PF03153.13 KFM62988.1 - 1.6 8.7 13.7 2.7 7.9 13.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit STT3 PF02516.14 KFM62989.1 - 5.9e-67 226.7 17.6 1.1e-61 209.2 13.6 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit SUKH_6 PF14568.6 KFM62989.1 - 0.2 12.1 1.1 6.3 7.2 0.0 2.9 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall STT3 PF02516.14 KFM62990.1 - 3.7e-74 250.4 15.7 4.1e-74 250.3 15.7 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 KFM62990.1 - 4e-10 40.1 5.7 4e-10 40.1 5.7 1.9 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MH2 PF03166.14 KFM62992.1 - 1e-28 100.9 0.1 1.5e-28 100.3 0.1 1.3 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.9 KFM62992.1 - 1.3e-05 25.0 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 HTH_Tnp_Tc3_2 PF01498.18 KFM62993.1 - 5.8e-16 58.5 2.2 5.8e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62993.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62993.1 - 2.3e-07 30.5 0.5 1.4e-06 28.0 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62993.1 - 0.00078 19.2 0.3 0.0023 17.7 0.3 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM62993.1 - 0.0096 16.0 0.2 0.038 14.1 0.2 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM62993.1 - 0.26 11.9 13.9 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM62994.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM62994.1 - 2.8e-13 49.9 0.0 4.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM62994.1 - 1.9e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM62994.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM62994.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM62995.1 - 5.1e-05 23.0 0.0 8.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Endonuclease_7 PF02945.15 KFM62998.1 - 5.2e-06 26.3 2.7 5.2e-06 26.3 2.7 2.0 2 0 0 2 2 2 1 Recombination endonuclease VII Transposase_1 PF01359.18 KFM62999.1 - 1.2e-21 76.3 0.2 2.8e-21 75.1 0.2 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_32 PF13565.6 KFM62999.1 - 4.8e-07 30.3 0.6 2.5e-06 28.0 0.1 2.7 3 1 0 3 3 3 1 Homeodomain-like domain DDE_3 PF13358.6 KFM62999.1 - 0.00013 21.7 0.0 0.00024 20.9 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease LAS2 PF15792.5 KFM62999.1 - 0.054 14.0 0.7 0.11 13.0 0.7 1.5 1 0 0 1 1 1 0 Lung adenoma susceptibility protein 2 HTH_Tnp_Tc3_2 PF01498.18 KFM62999.1 - 0.08 13.2 0.3 0.33 11.2 0.3 2.0 2 0 0 2 2 2 0 Transposase HTH_29 PF13551.6 KFM62999.1 - 0.081 13.0 0.0 0.31 11.1 0.0 2.1 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM63000.1 - 2.6e-14 53.2 1.0 4.9e-14 52.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63000.1 - 6e-14 52.0 0.0 7.8e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63001.1 - 5e-16 58.7 3.5 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63001.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63001.1 - 1.6e-06 27.8 0.6 7.9e-06 25.5 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63001.1 - 0.039 13.8 0.2 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain rve PF00665.26 KFM63002.1 - 7.9e-27 93.8 0.0 5.2e-26 91.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 KFM63002.1 - 0.00094 18.9 0.1 0.0019 18.0 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KFM63002.1 - 0.0013 19.0 0.2 0.007 16.6 0.0 2.0 2 0 0 2 2 2 1 DDE domain TRI5 PF06330.11 KFM63002.1 - 0.0051 15.7 0.0 0.007 15.3 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Integrase_H2C2 PF17921.1 KFM63002.1 - 0.064 13.4 0.7 0.14 12.2 0.7 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain E2 PF08199.11 KFM63002.1 - 0.1 12.5 1.6 0.18 11.8 0.3 2.1 2 0 0 2 2 2 0 Bacteriophage E2-like protein ATG101 PF07855.12 KFM63004.1 - 3e-41 141.0 0.0 3.7e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 SIP1 PF04938.12 KFM63005.1 - 1.1e-59 201.8 0.1 1.4e-59 201.5 0.1 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) BRCT PF00533.26 KFM63006.1 - 8e-41 138.3 11.1 7.2e-13 48.7 0.2 5.7 5 0 0 5 5 5 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFM63006.1 - 3.2e-35 119.9 13.2 1.5e-17 63.3 0.5 4.6 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 KFM63006.1 - 1.7e-19 70.0 13.0 3.5e-05 24.1 0.2 6.1 5 0 0 5 5 5 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFM63006.1 - 1.5e-14 53.7 3.4 4.5e-12 45.7 0.0 4.8 5 0 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KFM63006.1 - 4.7e-10 39.6 5.5 0.0034 17.6 0.2 5.3 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain Pentapeptide PF00805.22 KFM63006.1 - 3.2e-07 29.9 0.2 0.065 12.9 0.0 4.9 4 1 0 4 4 4 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KFM63006.1 - 1.3e-06 28.5 4.9 0.035 14.3 0.1 4.6 3 2 1 4 4 4 2 Pentapeptide repeats (9 copies) BRCT PF00533.26 KFM63007.1 - 0.00028 21.2 0.0 0.00033 21.0 0.0 1.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFM63007.1 - 0.0011 18.8 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KFM63007.1 - 0.017 15.5 0.0 0.019 15.4 0.0 1.1 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain NuA4 PF09340.10 KFM63008.1 - 6.7e-27 93.2 0.9 6.7e-27 93.2 0.9 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 SR-25 PF10500.9 KFM63008.1 - 0.069 12.8 10.3 0.12 12.0 10.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HTH_Tnp_Tc3_2 PF01498.18 KFM63009.1 - 2.3e-16 59.8 2.2 6.4e-16 58.4 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63009.1 - 1.3e-13 51.0 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63009.1 - 3.2e-07 30.0 1.6 7.8e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63009.1 - 0.003 17.3 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain DUF1754 PF08555.10 KFM63010.1 - 0.0001 23.1 23.0 0.00052 20.8 19.4 2.5 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) GEP5 PF17053.5 KFM63010.1 - 0.00075 19.4 2.6 0.00099 19.0 2.6 1.1 1 0 0 1 1 1 1 Genetic interactor of prohibitin 5 CortBP2 PF09727.9 KFM63010.1 - 0.08 12.8 10.5 0.088 12.7 10.5 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 MAS20 PF02064.15 KFM63010.1 - 0.1 12.7 6.2 0.12 12.5 6.2 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor Vps39_2 PF10367.9 KFM63010.1 - 0.86 10.1 7.2 0.27 11.7 1.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 DNA_pack_N PF02500.15 KFM63011.1 - 0.04 13.7 0.0 0.045 13.6 0.0 1.0 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus WHIM1 PF15612.6 KFM63011.1 - 0.11 12.0 0.3 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 PIN_4 PF13638.6 KFM63014.1 - 1.5e-09 38.3 0.0 1.7e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 PIN domain COE1_HLH PF16423.5 KFM63014.1 - 0.025 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain 2-Hacid_dh_C PF02826.19 KFM63015.1 - 4.8e-42 143.3 0.0 6.4e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFM63015.1 - 0.0047 17.1 0.0 0.007 16.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KFM63015.1 - 0.0077 15.9 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HTH_Tnp_Tc3_2 PF01498.18 KFM63016.1 - 2.6e-16 59.6 2.8 5e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63016.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63016.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63016.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63016.1 - 0.025 14.7 0.4 0.081 13.1 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM63016.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM63017.1 - 1.4e-07 31.4 0.0 2.8e-07 30.4 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease SH3_1 PF00018.28 KFM63018.1 - 1.7e-45 152.4 3.9 4.2e-14 51.9 0.2 3.3 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 KFM63018.1 - 5.1e-42 141.5 0.6 8.4e-14 51.2 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 KFM63018.1 - 6.4e-32 109.0 1.5 9.7e-12 44.4 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_10 PF17902.1 KFM63018.1 - 5.7e-09 35.9 1.5 0.0001 22.3 0.0 3.4 3 0 0 3 3 3 2 SH3 domain SH3_3 PF08239.11 KFM63018.1 - 9.2e-09 35.5 4.0 0.012 15.9 0.0 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain SH2 PF00017.24 KFM63018.1 - 5.9e-06 26.3 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 SH2 domain hSH3 PF14603.6 KFM63018.1 - 3e-05 24.3 0.2 0.48 10.9 0.2 2.5 2 0 0 2 2 2 2 Helically-extended SH3 domain HTH_Tnp_Tc3_2 PF01498.18 KFM63020.1 - 5e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63020.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63020.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63020.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63020.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Trypsin PF00089.26 KFM63021.1 - 3.3e-57 193.8 0.1 4.2e-57 193.5 0.1 1.1 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFM63021.1 - 5.8e-23 81.3 0.0 1.4e-22 80.1 0.0 1.6 2 0 0 2 2 2 1 CUB domain DUF1986 PF09342.11 KFM63021.1 - 4.4e-08 33.5 0.0 3.3e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.18 KFM63021.1 - 9e-08 32.2 10.3 9e-08 32.2 10.3 2.1 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Trypsin_2 PF13365.6 KFM63021.1 - 5e-07 30.7 0.0 8.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KFM63021.1 - 0.0056 16.3 0.0 0.61 9.6 0.0 2.2 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 LRR_8 PF13855.6 KFM63022.1 - 3.5e-17 61.9 8.3 4.8e-13 48.7 3.1 3.7 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KFM63022.1 - 4.5e-14 52.3 16.2 1e-08 35.3 1.0 4.0 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM63022.1 - 0.0032 17.8 9.2 3.7 8.5 0.1 5.6 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 KFM63022.1 - 0.011 15.8 11.6 0.31 11.2 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Selenoprotein_S PF06936.11 KFM63022.1 - 0.039 13.8 4.4 0.061 13.1 4.4 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF393 PF04134.12 KFM63022.1 - 0.043 15.2 0.6 0.11 13.9 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF393 Borrelia_P83 PF05262.11 KFM63022.1 - 0.23 9.9 7.3 0.29 9.6 7.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein BTB_2 PF02214.22 KFM63023.1 - 1.9e-16 60.2 0.0 3.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFM63023.1 - 0.0013 18.9 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain EGF PF00008.27 KFM63024.1 - 7.1e-05 23.0 7.5 7.1e-05 23.0 7.5 8.0 4 2 2 6 6 6 2 EGF-like domain EGF_MSP1_1 PF12946.7 KFM63024.1 - 0.0084 16.1 10.3 0.0084 16.1 10.3 7.2 5 3 2 7 7 7 3 MSP1 EGF domain 1 hEGF PF12661.7 KFM63024.1 - 0.08 13.6 6.5 0.08 13.6 6.5 9.3 7 3 2 9 9 9 0 Human growth factor-like EGF Tcell_CD4_C PF12104.8 KFM63024.1 - 1.4 8.9 7.6 0.33 10.9 0.4 3.0 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region HTH_Tnp_Tc3_2 PF01498.18 KFM63026.1 - 5.3e-16 58.6 3.5 6e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63026.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63026.1 - 2.3e-07 30.5 1.2 7.4e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63026.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63026.1 - 0.03 14.4 0.4 0.095 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM63026.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-C4 PF00105.18 KFM63027.1 - 4.2e-30 104.0 14.4 9.1e-30 102.9 14.4 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFM63027.1 - 2.7e-15 56.5 4.2 4.4e-14 52.5 4.2 2.2 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor HSM3_N PF18795.1 KFM63027.1 - 0.074 12.5 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain DUF2650 PF10853.8 KFM63028.1 - 0.013 15.2 0.2 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Ig_2 PF13895.6 KFM63029.1 - 1.7e-09 37.9 0.1 3.2e-06 27.4 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFM63029.1 - 1.6e-07 31.8 0.2 3.7e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM63029.1 - 6.7e-05 23.0 0.1 0.00022 21.4 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 KFM63029.1 - 0.0028 17.7 0.1 0.011 15.8 0.0 2.0 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_5 PF16681.5 KFM63029.1 - 0.0033 17.8 0.8 0.22 12.0 0.3 2.9 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ig PF00047.25 KFM63029.1 - 0.0036 17.4 0.3 0.51 10.5 0.1 2.9 2 1 0 2 2 2 1 Immunoglobulin domain V-set_CD47 PF08204.11 KFM63029.1 - 0.01 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Ig_4 PF16680.5 KFM63029.1 - 0.012 15.8 0.5 3.4 8.0 0.0 2.6 2 1 1 3 3 3 0 T-cell surface glycoprotein CD3 delta chain DDE_3 PF13358.6 KFM63030.1 - 3.2e-15 56.2 0.0 4.1e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM63031.1 - 5.3e-16 58.7 0.1 7.4e-15 55.0 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63031.1 - 7.9e-16 58.1 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63031.1 - 0.00079 20.0 1.5 0.00079 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63031.1 - 0.0017 18.1 0.0 0.064 13.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63031.1 - 0.014 15.6 0.1 0.051 13.7 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM63031.1 - 0.024 14.7 2.1 0.034 14.2 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM63031.1 - 0.029 14.2 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase DDE_Tnp_1_7 PF13843.6 KFM63035.1 - 1.6e-12 47.5 0.5 2e-12 47.1 0.5 1.2 1 0 0 1 1 1 1 Transposase IS4 LuxE PF04443.12 KFM63035.1 - 0.028 13.5 0.1 0.033 13.2 0.1 1.1 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE GIDE PF12483.8 KFM63036.1 - 2.3e-19 69.3 0.0 4.1e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.6 KFM63036.1 - 7.6e-11 41.7 15.6 1.6e-10 40.7 15.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM63036.1 - 0.00021 21.1 12.7 0.00048 19.9 12.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFM63036.1 - 0.033 14.2 14.4 0.084 12.9 14.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFM63036.1 - 0.3 11.5 18.2 0.42 11.0 16.1 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 KFM63036.1 - 1.9 8.4 13.6 8.1 6.4 12.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_A17 PF05380.13 KFM63037.1 - 1e-54 184.9 0.0 2.4e-54 183.7 0.0 1.7 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 KFM63037.1 - 7.9e-29 100.5 1.2 2.3e-28 99.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF5641 PF18701.1 KFM63037.1 - 3.8e-20 71.9 0.2 3.8e-20 71.9 0.2 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5641) rve PF00665.26 KFM63037.1 - 2.9e-10 40.4 0.0 1.5e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM63037.1 - 2.7e-09 37.0 1.6 2.7e-09 37.0 1.6 3.4 3 0 0 3 3 3 1 Integrase zinc binding domain RVT_1 PF00078.27 KFM63037.1 - 9e-08 31.9 0.1 2.2e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 KFM63037.1 - 0.0025 17.6 0.1 0.72 9.6 0.0 2.6 1 1 1 2 2 2 2 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 KFM63037.1 - 0.016 15.4 0.6 0.016 15.4 0.6 2.5 2 0 0 2 2 2 0 H2C2 zinc finger Spc7 PF08317.11 KFM63037.1 - 0.061 12.2 9.8 0.12 11.3 9.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Ion_trans_2 PF07885.16 KFM63038.1 - 1.8e-15 56.6 5.1 3.1e-15 55.9 5.1 1.3 1 0 0 1 1 1 1 Ion channel MFS_Mycoplasma PF07672.13 KFM63038.1 - 0.072 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter Ion_trans PF00520.31 KFM63038.1 - 0.13 11.4 2.7 0.21 10.8 2.7 1.2 1 0 0 1 1 1 0 Ion transport protein Thyroglobulin_1 PF00086.18 KFM63039.1 - 7.1e-34 115.3 23.8 3.5e-18 65.0 6.5 3.2 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.9 KFM63039.1 - 6.8e-22 77.9 14.9 4.4e-16 59.2 1.4 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.6 KFM63039.1 - 1.6e-12 47.7 6.4 6e-06 26.6 0.4 2.9 3 0 0 3 3 3 2 EF-hand domain pair Kazal_2 PF07648.15 KFM63039.1 - 1.1e-08 35.1 5.7 1.1e-08 35.1 5.7 3.3 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.6 KFM63039.1 - 1.6e-07 30.7 2.1 0.39 10.8 0.3 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFM63039.1 - 1.5e-06 27.3 1.1 3.4 7.4 0.1 4.6 4 0 0 4 4 4 3 EF hand Kazal_1 PF00050.21 KFM63039.1 - 1.6e-06 28.0 5.3 1.6e-06 28.0 5.3 3.2 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_5 PF13202.6 KFM63039.1 - 0.033 13.7 0.8 45 3.8 0.3 4.0 4 0 0 4 4 4 0 EF hand HTH_Tnp_Tc3_2 PF01498.18 KFM63040.1 - 2.7e-16 59.6 2.2 4.8e-16 58.8 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63040.1 - 1.4e-13 50.9 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease La PF05383.17 KFM63044.1 - 7.6e-23 80.3 0.2 9e-23 80.1 0.2 1.1 1 0 0 1 1 1 1 La domain Otopetrin PF03189.13 KFM63048.1 - 2.4e-102 343.0 13.4 2.7e-102 342.9 13.4 1.0 1 0 0 1 1 1 1 Otopetrin DUF4131 PF13567.6 KFM63048.1 - 0.97 9.1 6.2 1.8 8.2 3.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ets PF00178.22 KFM63049.1 - 1.5e-36 124.7 0.3 2.2e-36 124.1 0.3 1.2 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.17 KFM63049.1 - 0.087 13.4 0.1 0.14 12.8 0.1 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding ubiquitin PF00240.23 KFM63050.1 - 1.8e-08 34.0 0.2 3.9e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KFM63050.1 - 0.0017 18.5 0.1 0.0038 17.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFM63050.1 - 0.0033 18.0 0.0 0.0081 16.7 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF3385 PF11865.8 KFM63051.1 - 0.11 12.4 0.6 6 6.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 KFM63051.1 - 0.12 12.8 0.0 5.9 7.3 0.0 2.8 2 1 1 3 3 3 0 HEAT repeats Phage_term_smal PF05944.12 KFM63051.1 - 0.14 12.1 0.1 37 4.3 0.0 2.9 2 1 1 3 3 3 0 Phage small terminase subunit Membr_traf_MHD PF10540.9 KFM63052.1 - 4e-05 23.8 0.1 5e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain HTH_Tnp_Tc3_2 PF01498.18 KFM63053.1 - 3.2e-12 46.5 3.9 3.2e-12 46.5 3.9 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63053.1 - 8.6e-10 38.5 0.0 1.2e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM63053.1 - 0.0013 19.3 0.7 0.0013 19.3 0.7 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 KFM63053.1 - 0.013 15.1 0.3 0.029 14.0 0.3 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_12 PF08461.10 KFM63053.1 - 0.024 14.6 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain TraG-D_C PF12696.7 KFM63055.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG zf-CCHC PF00098.23 KFM63057.1 - 9.1e-06 25.5 1.4 1.4e-05 25.0 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM63057.1 - 0.0036 17.0 0.4 0.0062 16.2 0.4 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM63057.1 - 0.085 12.6 0.7 0.14 11.9 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle LigT_PEase PF02834.16 KFM63059.1 - 0.058 13.6 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 LigT like Phosphoesterase I-set PF07679.16 KFM63060.1 - 3.1e-18 65.6 0.0 2.6e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM63060.1 - 1.2e-17 64.2 0.1 2.1e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM63060.1 - 2.1e-14 53.5 0.2 1.5e-07 31.5 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFM63060.1 - 3.2e-14 53.0 1.3 6.2e-07 29.6 0.4 3.2 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM63060.1 - 2.4e-10 40.6 0.1 9.1e-07 29.1 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFM63060.1 - 0.0001 21.8 0.0 0.035 13.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFM63060.1 - 0.0081 16.5 0.1 0.21 12.0 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 KFM63060.1 - 0.025 14.8 0.1 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Lep_receptor_Ig PF06328.11 KFM63060.1 - 0.083 12.9 0.0 4.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Ig-like C2-type domain FeS_assembly_P PF01883.19 KFM63061.1 - 2.3e-10 40.5 0.0 4.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein WHEP-TRS PF00458.20 KFM63062.1 - 1.5e-11 44.2 2.8 1.6e-11 44.2 1.3 1.8 2 0 0 2 2 2 1 WHEP-TRS domain IMD PF08397.11 KFM63063.1 - 1.5e-10 40.9 0.0 1.6e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 IRSp53/MIM homology domain Smac_DIABLO PF09057.10 KFM63063.1 - 0.05 13.0 0.0 0.08 12.3 0.0 1.3 1 1 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases BTB PF00651.31 KFM63064.1 - 3.8e-22 78.6 1.2 4.9e-22 78.3 1.2 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFM63065.1 - 5e-22 78.2 0.8 6.3e-20 71.5 0.0 2.6 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM63065.1 - 3.2e-15 56.1 1.7 1e-14 54.4 0.8 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Ten1_2 PF15490.6 KFM63065.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit rve PF00665.26 KFM63066.1 - 3.5e-22 78.8 0.0 5.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain SDH_C PF18317.1 KFM63066.1 - 0.084 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain rve_3 PF13683.6 KFM63066.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain TIL PF01826.17 KFM63067.1 - 1.7e-143 466.9 278.5 7.1e-15 55.0 15.3 12.1 12 0 0 12 12 12 11 Trypsin Inhibitor like cysteine rich domain TsaE PF02367.17 KFM63068.1 - 0.063 13.3 0.1 0.074 13.1 0.1 1.1 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HTH_Tnp_Tc3_2 PF01498.18 KFM63069.1 - 1.5e-14 54.0 0.0 3.1e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63069.1 - 7.7e-14 51.7 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Claudin_3 PF06653.11 KFM63070.1 - 1.7e-05 24.8 5.3 3.1e-05 24.0 5.3 1.4 1 1 0 1 1 1 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 KFM63070.1 - 9.6e-05 22.3 2.1 0.00025 20.9 2.3 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF3169 PF11368.8 KFM63070.1 - 0.57 9.6 5.0 0.083 12.4 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Toxin_9 PF02819.15 KFM63071.1 - 3.3e-05 24.1 12.7 4.4e-05 23.7 12.7 1.3 1 0 0 1 1 1 1 Spider toxin Agouti PF05039.12 KFM63071.1 - 0.064 14.0 9.7 0.076 13.7 9.7 1.1 1 0 0 1 1 1 0 Agouti protein Toxin_35 PF10530.9 KFM63071.1 - 0.63 10.1 15.3 1.7 8.7 15.3 1.6 1 1 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold HTH_Tnp_Tc3_2 PF01498.18 KFM63073.1 - 2.2e-16 59.8 2.2 4e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63073.1 - 8.3e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MFS_1_like PF12832.7 KFM63074.1 - 3.3e-35 121.7 11.0 4.2e-35 121.3 11.0 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM63074.1 - 9.4e-10 37.9 18.3 2.2e-05 23.6 0.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFM63074.1 - 3.3e-05 23.1 4.9 4.5e-05 22.6 4.9 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter BT1 PF03092.16 KFM63074.1 - 0.0071 14.6 0.6 0.041 12.1 0.6 1.9 1 1 0 1 1 1 1 BT1 family LacY_symp PF01306.19 KFM63074.1 - 0.068 11.9 9.3 0.087 11.6 9.3 1.0 1 0 0 1 1 1 0 LacY proton/sugar symporter DUF4083 PF13314.6 KFM63074.1 - 0.34 10.9 0.2 0.34 10.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) MFS_1_like PF12832.7 KFM63075.1 - 1.1e-14 54.1 0.1 1.2e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM63075.1 - 2.8e-07 29.8 0.0 3.4e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM63075.1 - 0.0051 15.7 0.6 0.0084 15.0 0.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter LacY_symp PF01306.19 KFM63075.1 - 0.024 13.4 0.6 0.033 13.0 0.6 1.1 1 0 0 1 1 1 0 LacY proton/sugar symporter MFS_1_like PF12832.7 KFM63076.1 - 1.8e-35 122.6 12.2 2.1e-35 122.3 12.2 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM63076.1 - 9.5e-10 37.9 20.5 1.3e-09 37.5 20.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 KFM63076.1 - 0.0024 16.7 10.7 0.003 16.4 10.7 1.0 1 0 0 1 1 1 1 LacY proton/sugar symporter Sugar_tr PF00083.24 KFM63076.1 - 0.17 10.7 13.9 0.061 12.2 9.5 2.1 1 1 1 2 2 2 0 Sugar (and other) transporter Amastin PF07344.11 KFM63076.1 - 0.53 10.1 11.8 4 7.3 0.4 3.1 2 1 1 3 3 3 0 Amastin surface glycoprotein MFS_1_like PF12832.7 KFM63078.1 - 6.5e-72 242.5 14.1 7.9e-72 242.2 14.1 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM63078.1 - 2.6e-17 62.8 32.4 2.8e-09 36.4 22.4 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 KFM63078.1 - 2.6e-07 29.8 22.5 0.00095 18.0 16.7 2.5 2 1 0 2 2 2 2 LacY proton/sugar symporter Nuc_H_symport PF03825.16 KFM63078.1 - 7.1e-05 22.0 20.5 0.00091 18.3 17.5 2.2 2 0 0 2 2 2 2 Nucleoside H+ symporter MFS_1_like PF12832.7 KFM63079.1 - 1.5e-62 211.7 18.6 1.7e-62 211.5 18.6 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM63079.1 - 2.4e-17 62.9 36.7 3.5e-08 32.8 20.4 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 KFM63079.1 - 2.3e-05 23.4 0.5 2.3e-05 23.4 0.5 3.3 2 1 2 4 4 4 2 LacY proton/sugar symporter HTH_Tnp_Tc3_2 PF01498.18 KFM63080.1 - 5.3e-33 113.1 11.2 1.3e-15 57.4 2.2 3.4 3 0 0 3 3 3 2 Transposase DDE_3 PF13358.6 KFM63080.1 - 1.4e-28 99.5 0.0 6.7e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease Co_AT_N PF12557.8 KFM63080.1 - 0.0084 16.0 0.4 6.6 6.8 0.0 2.5 2 0 0 2 2 2 2 Cob(I)alamin adenosyltransferase N terminal NYD-SP12_N PF15015.6 KFM63080.1 - 0.018 13.4 0.1 4.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated, N-terminal ACAS_N PF16177.5 KFM63080.1 - 2.6 8.0 7.3 16 5.5 0.8 2.5 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus MFS_1_like PF12832.7 KFM63081.1 - 4.5e-69 233.1 13.7 5.4e-69 232.9 13.7 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM63081.1 - 9.7e-15 54.3 48.8 1.1e-06 27.9 25.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFM63081.1 - 0.00087 18.4 19.3 0.0056 15.7 0.2 2.3 2 0 0 2 2 2 2 Nucleoside H+ symporter CDP-OH_P_transf PF01066.21 KFM63082.1 - 2.7e-06 28.0 0.5 2.7e-06 28.0 0.5 2.8 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase CHORD PF04968.12 KFM63083.1 - 0.075 13.8 0.1 0.27 12.0 0.1 2.0 1 0 0 1 1 1 0 CHORD UQ_con PF00179.26 KFM63085.1 - 2.6e-13 49.8 0.0 6e-10 38.9 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM63085.1 - 1.6e-06 28.4 2.2 0.0018 18.6 0.8 2.6 1 1 1 2 2 2 2 RWD domain Josephin PF02099.17 KFM63085.1 - 0.027 14.6 0.0 0.091 12.9 0.0 2.1 1 1 0 1 1 1 0 Josephin Pox_polyA_pol PF03296.13 KFM63085.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain Spt5_N PF11942.8 KFM63085.1 - 0.18 12.8 6.1 0.35 11.9 6.1 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal 7tm_1 PF00001.21 KFM63086.1 - 2.8e-07 30.1 1.9 3.2e-07 30.0 1.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HTH_Tnp_Tc3_2 PF01498.18 KFM63087.1 - 8e-11 42.0 2.9 1.3e-10 41.4 2.1 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63087.1 - 1e-09 38.3 0.0 3.2e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63087.1 - 1.4e-05 24.7 0.4 8.5e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63087.1 - 0.0073 16.1 1.4 0.055 13.3 0.2 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_12 PF08461.10 KFM63087.1 - 0.078 12.9 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain Sigma70_r4_2 PF08281.12 KFM63087.1 - 0.15 11.7 2.1 1.8 8.3 0.0 3.4 4 0 0 4 4 4 0 Sigma-70, region 4 GATase_6 PF13522.6 KFM63088.1 - 8.6e-17 61.6 0.0 1.6e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFM63088.1 - 2.5e-13 50.0 0.0 4.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KFM63088.1 - 2e-06 27.4 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KFM63088.1 - 8.9e-05 21.5 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II 7tm_1 PF00001.21 KFM63089.1 - 6.8e-05 22.3 3.0 8.7e-05 22.0 2.1 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KFM63090.1 - 7.6e-05 22.2 1.2 8e-05 22.1 1.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ELMO_CED12 PF04727.13 KFM63090.1 - 0.18 11.9 0.0 0.19 11.8 0.0 1.0 1 0 0 1 1 1 0 ELMO/CED-12 family T-box PF00907.22 KFM63091.1 - 0.032 14.5 0.5 0.034 14.4 0.5 1.1 1 0 0 1 1 1 0 T-box Sugar_tr PF00083.24 KFM63092.1 - 5.9e-24 84.7 6.6 8.7e-24 84.2 6.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM63092.1 - 7.1e-17 61.4 2.9 1e-16 60.9 2.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2583 PF10762.9 KFM63092.1 - 0.21 12.0 2.2 0.34 11.4 1.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2583) ADH_N PF08240.12 KFM63094.1 - 6.2e-09 35.7 0.0 8.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM63095.1 - 3.5e-18 65.8 0.0 4.5e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM63095.1 - 0.00014 22.9 0.0 0.00019 22.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MAF_flag10 PF01973.18 KFM63095.1 - 0.024 14.3 0.2 0.58 9.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF115 HHH_9 PF17674.1 KFM63095.1 - 0.17 12.8 0.0 0.34 11.8 0.0 1.5 1 0 0 1 1 1 0 HHH domain WD40 PF00400.32 KFM63096.1 - 7.7e-09 36.0 14.1 0.0066 17.3 0.0 6.3 7 1 0 7 7 7 3 WD domain, G-beta repeat GNAT_acetyltr_2 PF13718.6 KFM63097.1 - 1.6e-84 282.8 0.1 1.7e-83 279.5 0.0 2.2 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KFM63097.1 - 1.5e-47 162.3 3.9 3e-47 161.3 3.9 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KFM63097.1 - 2.3e-18 66.7 0.6 5.6e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 Helicase Acetyltransf_7 PF13508.7 KFM63097.1 - 0.0033 17.8 0.0 0.025 15.0 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM63097.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1726 PF08351.11 KFM63098.1 - 5.9e-06 26.1 0.1 6.2e-06 26.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Organ_specific PF10950.8 KFM63100.1 - 0.13 13.0 1.7 0.17 12.6 1.7 1.4 1 1 0 1 1 1 0 Organ specific protein DUF3042 PF11240.8 KFM63100.1 - 0.79 9.8 6.5 1.5 8.9 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) SNF2_N PF00176.23 KFM63101.1 - 4.1e-24 85.0 0.1 5.5e-24 84.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM63101.1 - 3.8e-14 53.0 0.1 9.1e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM63101.1 - 4.4e-07 30.0 0.0 5.9e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KFM63101.1 - 1.5e-05 25.0 0.4 0.00037 20.5 0.0 2.7 3 0 0 3 3 3 1 Flavivirus DEAD domain ERCC3_RAD25_C PF16203.5 KFM63101.1 - 0.024 13.9 0.1 0.052 12.7 0.1 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Lamp PF01299.17 KFM63102.1 - 2.7e-09 37.0 0.0 3.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFM63102.1 - 0.03 14.1 0.4 0.059 13.2 0.0 1.6 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Pkinase PF00069.25 KFM63103.1 - 9.5e-70 235.0 0.0 1.2e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM63103.1 - 4.7e-43 147.3 0.0 6.8e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFM63103.1 - 4.5e-14 52.6 0.1 1.3e-13 51.0 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFM63103.1 - 2.1e-06 27.3 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM63103.1 - 6e-05 22.0 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase KIND PF16474.5 KFM63103.1 - 0.031 14.2 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain APH PF01636.23 KFM63103.1 - 0.037 14.0 0.7 0.88 9.4 0.1 2.8 1 1 2 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM63103.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFM63103.1 - 0.18 10.7 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pullulanase_Ins PF18494.1 KFM63105.1 - 0.13 12.8 0.0 0.69 10.4 0.0 2.1 2 0 0 2 2 2 0 Pullulanase Ins domain zf-H2C2_2 PF13465.6 KFM63106.1 - 4.4e-62 203.9 58.2 5.8e-08 32.8 0.3 10.1 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63106.1 - 3.2e-47 156.4 78.9 2.9e-06 27.4 1.6 9.4 10 0 0 10 10 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63106.1 - 3.4e-35 117.6 67.4 0.00028 21.4 0.9 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM63106.1 - 1.3e-23 82.6 61.0 0.0023 18.3 0.6 9.2 9 0 0 9 9 9 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM63106.1 - 1.7e-23 82.1 54.1 0.00013 21.8 0.2 9.4 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM63106.1 - 6.7e-21 74.1 43.1 0.0074 16.6 0.4 9.3 9 0 0 9 9 9 8 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM63106.1 - 8.9e-12 44.7 33.0 0.19 11.6 0.1 9.1 1 1 8 9 9 9 6 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 KFM63106.1 - 3.5e-10 39.4 55.4 0.15 11.9 0.8 9.8 10 0 0 10 10 10 7 C2H2-type zinc-finger domain GAGA PF09237.11 KFM63106.1 - 9.1e-09 35.0 24.1 0.2 11.5 0.2 8.3 1 1 8 9 9 9 3 GAGA factor zf-C2H2_2 PF12756.7 KFM63106.1 - 6.8e-07 29.6 57.9 0.92 9.9 1.1 8.9 1 1 8 9 9 9 6 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM63106.1 - 1.7e-05 24.7 24.0 0.0041 17.1 0.9 6.4 2 2 6 8 8 8 1 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM63106.1 - 1.7e-05 24.3 36.5 1.5 8.4 0.2 8.8 5 1 4 9 9 9 2 MYST family zinc finger domain zf-RRPl_C4 PF17026.5 KFM63106.1 - 2e-05 24.7 28.9 0.068 13.3 3.8 3.7 1 1 2 3 3 3 3 Putative ribonucleoprotein zinc-finger pf C4 type TRAF6_Z2 PF18048.1 KFM63106.1 - 2.9e-05 24.1 50.1 0.17 12.0 0.4 10.0 10 0 0 10 10 10 4 TNF receptor-associated factor 6 zinc finger 2 Prok-RING_1 PF14446.6 KFM63106.1 - 6.9e-05 22.7 33.1 5.6 7.0 0.1 8.9 9 0 0 9 9 9 1 Prokaryotic RING finger family 1 DUF2757 PF10955.8 KFM63106.1 - 0.0001 22.4 28.4 9.9 6.5 0.1 8.7 9 0 0 9 9 9 0 Protein of unknown function (DUF2757) GATA PF00320.27 KFM63106.1 - 0.0015 18.1 17.4 12 5.6 0.1 8.2 9 0 0 9 9 9 0 GATA zinc finger zf-DBF PF07535.12 KFM63106.1 - 0.0031 17.6 36.7 8.9 6.5 0.4 9.1 9 0 0 9 9 9 0 DBF zinc finger zinc_ribbon_15 PF17032.5 KFM63106.1 - 0.0043 17.8 33.1 1.5 9.6 1.9 5.0 1 1 2 5 5 5 3 zinc-ribbon family zf-C2H2_8 PF15909.5 KFM63106.1 - 0.0065 16.7 38.6 0.066 13.5 4.4 5.3 1 1 4 5 5 5 2 C2H2-type zinc ribbon AMP_N PF05195.16 KFM63106.1 - 0.0068 16.1 0.0 20 4.9 0.0 4.5 1 1 2 4 4 4 0 Aminopeptidase P, N-terminal domain HNH_5 PF14279.6 KFM63106.1 - 0.0079 16.0 37.9 1.7 8.6 1.0 8.1 4 3 2 6 6 6 2 HNH endonuclease C1_1 PF00130.22 KFM63106.1 - 0.017 15.0 42.6 4.9 7.1 2.8 8.3 2 2 3 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 KFM63106.1 - 0.021 14.9 29.8 8.8 6.5 0.2 8.5 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2039 PF10217.9 KFM63106.1 - 0.047 14.0 25.8 2.7 8.4 2.0 4.4 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2039) YyzF PF14116.6 KFM63106.1 - 0.067 13.2 25.1 19 5.4 0.1 8.5 9 0 0 9 9 9 0 YyzF-like protein zf_UBZ PF18439.1 KFM63106.1 - 0.11 12.1 45.5 1.4 8.6 0.3 9.0 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM63106.1 - 3 8.0 38.1 1.5 9.0 1.9 6.5 1 1 7 8 8 8 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.15 KFM63106.1 - 3.3 7.8 29.4 44 4.2 0.3 8.4 5 4 3 8 8 8 0 Sec23/Sec24 zinc finger Lipase_GDSL_2 PF13472.6 KFM63107.1 - 2.4e-08 34.6 0.0 3.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family WASH_WAHD PF11945.8 KFM63107.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 WAHD domain of WASH complex ADH_N PF08240.12 KFM63108.1 - 3.5e-08 33.3 0.1 8e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM63108.1 - 0.00052 20.0 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM63108.1 - 0.0017 19.4 0.0 0.0039 18.2 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Ank_2 PF12796.7 KFM63110.1 - 5.2e-17 62.2 0.0 2.3e-10 40.9 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM63110.1 - 6.9e-14 52.0 0.2 8.2e-07 29.5 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM63110.1 - 1.3e-10 40.5 0.5 0.0063 16.9 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFM63110.1 - 2.4e-08 34.1 0.2 0.00026 21.2 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM63110.1 - 2.8e-08 33.9 0.7 0.0031 17.9 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Alg14 PF08660.11 KFM63111.1 - 4.7e-65 218.8 0.1 6.9e-65 218.2 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like ResIII PF04851.15 KFM63111.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_transf_28 PF03033.20 KFM63111.1 - 0.036 14.1 0.0 0.071 13.1 0.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain GDP_Man_Dehyd PF16363.5 KFM63112.1 - 1.6e-13 50.8 0.0 1.8e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFM63112.1 - 3.1e-09 36.6 0.0 4e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFM63112.1 - 0.085 12.4 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family RrnaAD PF00398.20 KFM63112.1 - 0.24 10.4 0.0 0.34 9.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Glyco_hydro_20 PF00728.22 KFM63113.1 - 3.5e-90 302.9 1.6 6e-90 302.2 1.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KFM63113.1 - 1.8e-16 61.0 0.1 3.7e-15 56.8 0.0 2.8 2 2 1 3 3 3 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KFM63113.1 - 5.7e-07 30.4 0.0 1.3e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 FTA4 PF13093.6 KFM63115.1 - 0.093 12.6 1.5 0.13 12.2 1.5 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DRY_EERY PF09750.9 KFM63115.1 - 0.11 12.8 0.5 0.19 12.0 0.5 1.4 1 0 0 1 1 1 0 Alternative splicing regulator Defensin_2 PF01097.18 KFM63115.1 - 0.25 11.3 0.2 0.44 10.5 0.2 1.3 1 0 0 1 1 1 0 Arthropod defensin PIF1 PF05970.14 KFM63116.1 - 1.5e-59 202.0 0.4 1.8e-59 201.8 0.4 1.1 1 0 0 1 1 1 1 PIF1-like helicase DUF1279 PF06916.13 KFM63118.1 - 3.7e-22 78.7 0.3 4.3e-22 78.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DDE_3 PF13358.6 KFM63119.1 - 3.6e-16 59.2 0.1 4.9e-15 55.6 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63119.1 - 1.3e-10 41.3 1.0 2.3e-10 40.5 1.0 1.4 1 0 0 1 1 1 1 Transposase DUF1917 PF08939.10 KFM63120.1 - 0.00078 19.4 0.4 0.0017 18.3 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) DUF1917 PF08939.10 KFM63121.1 - 7e-06 26.1 0.2 1.1e-05 25.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DUF1917 PF08939.10 KFM63122.1 - 0.028 14.4 1.8 0.19 11.6 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1917) DUF1917 PF08939.10 KFM63123.1 - 0.0064 16.4 0.8 0.029 14.3 0.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) ANAPC4_WD40 PF12894.7 KFM63124.1 - 3.6e-07 30.4 0.0 4.5e-05 23.7 0.0 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ferritin-like PF12902.7 KFM63125.1 - 0.0082 16.0 1.7 0.014 15.3 1.3 1.6 1 1 0 1 1 1 1 Ferritin-like DUF3642 PF12182.8 KFM63125.1 - 0.082 13.2 0.3 0.082 13.2 0.3 2.1 2 0 0 2 2 2 0 Bacterial lipoprotein HrpB2 PF09487.10 KFM63125.1 - 0.17 12.3 2.4 0.32 11.4 0.3 2.4 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) DUF2746 PF10874.8 KFM63125.1 - 0.36 11.3 2.2 0.76 10.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) DASH_Dam1 PF08653.10 KFM63125.1 - 1.2 9.0 6.2 12 5.7 0.7 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF2779 PF11074.8 KFM63125.1 - 1.9 9.0 8.3 0.16 12.5 1.0 2.7 2 2 1 3 3 3 0 Domain of unknown function(DUF2779) HTH_Tnp_Tc3_2 PF01498.18 KFM63128.1 - 2.3e-16 59.8 2.2 4.1e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63128.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease VWC PF00093.18 KFM63129.1 - 0.014 15.7 10.5 0.014 15.7 10.5 13.8 4 2 7 11 11 11 0 von Willebrand factor type C domain HTH_Tnp_Tc3_2 PF01498.18 KFM63130.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63130.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Sina PF03145.16 KFM63131.1 - 1.1e-83 280.1 0.6 1.7e-83 279.5 0.6 1.3 1 0 0 1 1 1 1 Seven in absentia protein family Pkinase PF00069.25 KFM63132.1 - 2.1e-12 47.0 0.1 2.9e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM63132.1 - 1.9e-05 24.1 0.1 2.4e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase VF530 PF09905.9 KFM63132.1 - 0.17 12.1 0.0 0.51 10.6 0.0 1.8 1 0 0 1 1 1 0 DNA-binding protein VF530 CAP_GLY PF01302.25 KFM63133.1 - 0.039 14.0 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 CAP-Gly domain bZIP_1 PF00170.21 KFM63135.1 - 1.5e-08 34.6 7.2 2.7e-08 33.8 7.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM63135.1 - 2.6e-08 33.8 6.5 5.4e-08 32.8 6.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFM63135.1 - 0.0085 16.6 6.7 0.0085 16.6 6.7 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor BrkDBD PF09607.10 KFM63136.1 - 3e-09 36.5 0.5 5.1e-09 35.8 0.5 1.4 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_1 PF01527.20 KFM63136.1 - 0.0038 17.5 5.1 0.0057 16.9 4.9 1.4 1 1 0 1 1 1 1 Transposase L_HMGIC_fpl PF10242.9 KFM63137.1 - 6.9e-49 166.5 3.7 8.4e-49 166.2 3.7 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 KFM63137.1 - 1.2e-07 31.7 0.8 2.2e-07 30.9 0.8 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DoxD PF04173.13 KFM63137.1 - 0.045 13.7 2.8 5.9 6.8 0.1 2.4 2 0 0 2 2 2 0 TQO small subunit DoxD CbtA PF09490.10 KFM63137.1 - 3.8 7.2 6.6 0.4 10.4 1.2 1.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Cullin PF00888.22 KFM63138.1 - 2.6e-26 92.4 1.9 2.6e-26 92.4 1.9 1.7 2 0 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 KFM63138.1 - 1.5e-22 79.9 0.2 4.1e-22 78.5 0.2 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 NLRC4_HD2 PF17776.1 KFM63138.1 - 0.22 12.1 2.1 0.51 10.9 0.3 2.6 3 0 0 3 3 3 0 NLRC4 helical domain HD2 ANAPC4_WD40 PF12894.7 KFM63139.1 - 3.8e-11 43.1 0.0 0.0085 16.4 0.0 5.4 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM63139.1 - 5.2e-07 30.3 0.4 0.012 16.5 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KFM63139.1 - 0.1 11.1 0.1 0.44 9.0 0.0 1.8 1 1 1 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 KFM63139.1 - 0.1 12.5 0.4 1.6 8.5 0.0 2.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A HTH_Tnp_Tc3_2 PF01498.18 KFM63140.1 - 4.3e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63140.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63140.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63140.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63140.1 - 1.7 9.3 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63141.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63141.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63142.1 - 3.9e-16 59.0 2.2 3.9e-16 59.0 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63142.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63143.1 - 4e-16 59.0 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63143.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63143.1 - 3.2e-07 30.0 1.6 7.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63143.1 - 0.003 17.3 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63143.1 - 0.033 14.3 0.4 0.099 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM63143.1 - 2.9 8.6 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Abhydro_lipase PF04083.16 KFM63144.1 - 2.2e-24 84.8 0.0 4.9e-24 83.7 0.0 1.6 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KFM63144.1 - 3.7e-18 66.1 0.0 5.2e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM63144.1 - 9.2e-07 28.4 0.0 1.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KFM63144.1 - 0.0034 16.3 0.0 0.0096 14.8 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Esterase PF00756.20 KFM63144.1 - 0.0038 16.9 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase KCT2 PF17818.1 KFM63145.1 - 1.1e-05 25.7 1.4 1.1e-05 25.7 1.4 2.7 3 1 1 4 4 4 1 Keratinocyte-associated gene product Calsarcin PF05556.11 KFM63146.1 - 0.00021 20.9 0.3 0.0054 16.3 0.3 2.7 1 1 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) DDE_Tnp_IS1595 PF12762.7 KFM63147.1 - 6.9e-14 52.1 0.0 8.8e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain zf-H2C2_2 PF13465.6 KFM63149.1 - 1.3e-91 297.3 105.4 5.1e-10 39.3 1.2 14.1 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63149.1 - 4.2e-69 225.3 113.7 1.8e-06 28.0 3.4 14.0 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63149.1 - 2.4e-49 161.7 104.1 0.0002 21.9 0.7 13.4 14 0 0 14 14 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM63149.1 - 3.3e-46 154.4 99.1 4.3e-05 23.8 1.5 13.5 13 0 0 13 13 13 13 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63149.1 - 5e-28 96.8 78.0 0.005 17.1 0.7 13.4 12 1 1 13 13 13 13 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM63149.1 - 2.5e-20 71.9 71.9 0.0027 17.7 0.3 12.7 12 0 0 12 12 12 10 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM63149.1 - 1.1e-19 70.2 41.3 0.089 12.9 0.0 12.7 8 3 5 13 13 13 6 Sec23/Sec24 zinc finger BolA PF01722.18 KFM63149.1 - 1.1e-12 48.1 17.6 0.38 11.1 0.2 9.4 2 2 4 8 8 8 4 BolA-like protein zf-C2H2_11 PF16622.5 KFM63149.1 - 3.5e-12 45.9 64.4 0.15 11.9 0.4 12.6 13 0 0 13 13 13 7 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM63149.1 - 7.2e-08 32.0 88.7 0.043 13.6 0.8 13.2 13 1 0 13 13 13 5 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM63149.1 - 1.8e-07 30.9 48.9 1.8 8.6 0.1 12.4 12 0 0 12 12 12 3 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM63149.1 - 1.4e-06 29.0 52.9 0.11 13.2 1.3 7.1 4 2 4 8 8 8 5 zinc-ribbon family zf-DBF PF07535.12 KFM63149.1 - 9.6e-06 25.6 62.7 3.7 7.7 0.1 12.7 13 0 0 13 13 13 1 DBF zinc finger zf-C2H2_9 PF16293.5 KFM63149.1 - 1.4e-05 24.8 62.0 1.9 8.4 0.1 12.9 2 1 11 13 13 13 2 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM63149.1 - 2.2e-05 24.5 61.2 0.49 10.5 7.3 6.3 1 1 7 8 8 8 7 Putative ribonucleoprotein zinc-finger pf C4 type zinc-ribbons_6 PF07191.12 KFM63149.1 - 0.00014 21.7 54.7 0.44 10.5 6.5 9.9 1 1 8 9 9 9 1 zinc-ribbons Zf_RING PF16744.5 KFM63149.1 - 0.0019 18.3 60.2 9.5 6.4 0.1 12.4 1 1 11 12 12 12 0 KIAA1045 RING finger GAGA PF09237.11 KFM63149.1 - 0.0035 17.1 25.6 11 5.9 0.1 9.3 1 1 10 12 12 12 0 GAGA factor zf-C2H2_2 PF12756.7 KFM63149.1 - 0.0046 17.3 94.2 1.6 9.1 0.5 12.8 1 1 11 12 12 12 2 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFM63149.1 - 0.0055 16.6 67.6 4.8 7.1 2.6 10.9 2 2 10 12 12 12 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 KFM63149.1 - 0.0084 16.2 51.2 35 4.6 0.2 12.6 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) Baculo_IE-1 PF05290.11 KFM63149.1 - 0.016 15.1 49.0 15 5.5 0.1 10.3 1 1 6 7 7 7 0 Baculovirus immediate-early protein (IE-0) CIA30 PF08547.12 KFM63149.1 - 0.022 14.8 0.0 0.61 10.1 0.0 3.2 2 1 2 4 4 4 0 Complex I intermediate-associated protein 30 (CIA30) Zn-ribbon_8 PF09723.10 KFM63149.1 - 0.032 14.3 49.7 5.2 7.3 1.8 8.6 3 2 6 10 10 10 0 Zinc ribbon domain Tox-HNH-HHH PF15637.6 KFM63149.1 - 0.07 13.3 8.8 22 5.3 0.0 5.0 1 1 4 6 6 6 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-MYST PF17772.1 KFM63149.1 - 0.12 12.0 73.1 1.1 8.9 0.3 12.6 4 4 9 13 13 13 0 MYST family zinc finger domain C1_4 PF07975.12 KFM63149.1 - 0.71 10.1 64.2 1.1 9.5 5.3 9.1 1 1 12 13 13 13 0 TFIIH C1-like domain Mga PF05043.13 KFM63149.1 - 1.8 9.2 7.6 14 6.4 0.1 4.4 4 3 1 5 5 5 0 Mga helix-turn-helix domain DUF2039 PF10217.9 KFM63149.1 - 3.2 8.1 59.8 4.2 7.8 5.3 6.2 1 1 6 7 7 7 0 Uncharacterized conserved protein (DUF2039) Prok-RING_1 PF14446.6 KFM63149.1 - 5.1 7.1 55.8 2.8 7.9 0.3 12.4 13 0 0 13 13 13 0 Prokaryotic RING finger family 1 PWWP PF00855.17 KFM63150.1 - 2.9e-07 30.8 1.4 4e-06 27.2 1.4 2.5 1 1 0 1 1 1 1 PWWP domain Bromodomain PF00439.25 KFM63150.1 - 0.00023 21.2 0.0 0.00061 19.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain zf-RING_2 PF13639.6 KFM63150.1 - 2.4 8.6 17.3 0.49 10.8 13.2 2.0 2 0 0 2 2 2 0 Ring finger domain zf-MYND PF01753.18 KFM63151.1 - 0.024 14.7 17.0 0.024 14.7 17.0 2.7 2 0 0 2 2 2 0 MYND finger OmpH PF03938.14 KFM63151.1 - 0.7 10.2 0.0 0.7 10.2 0.0 2.5 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 KFM63151.1 - 9.2 6.7 14.0 14 6.1 11.8 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DDE_3 PF13358.6 KFM63152.1 - 1.2e-07 31.6 0.0 1.2e-07 31.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63153.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63153.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63154.1 - 2.9e-16 59.4 1.4 6.5e-16 58.3 1.4 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63154.1 - 1.9e-05 25.2 7.8 8.7e-05 23.1 3.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63154.1 - 0.00064 19.8 4.3 0.0095 16.0 0.7 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_33 PF13592.6 KFM63154.1 - 0.068 12.8 0.2 0.068 12.8 0.2 1.8 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM63155.1 - 1.7e-08 34.3 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Hydrolase_like PF13242.6 KFM63156.1 - 1.8e-23 82.4 0.0 2e-22 79.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 KFM63156.1 - 1.9e-08 34.6 0.0 3.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM63156.1 - 8.6e-07 29.4 0.4 1.4e-06 28.7 0.4 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C2H2 PF00096.26 KFM63157.1 - 0.00036 20.8 2.0 0.00036 20.8 2.0 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63157.1 - 0.0007 20.2 3.0 0.0011 19.6 1.7 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM63157.1 - 0.0032 17.2 1.2 0.0057 16.4 1.2 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM63157.1 - 0.012 15.5 0.3 0.022 14.7 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.15 KFM63157.1 - 0.015 15.3 0.3 0.035 14.1 0.3 1.6 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.6 KFM63157.1 - 0.048 14.1 3.3 3.1 8.4 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM63157.1 - 10 6.0 8.1 5.8 6.8 4.7 2.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Hydrolase_like PF13242.6 KFM63159.1 - 2.4e-17 62.8 0.0 3.3e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KFM63159.1 - 1.2e-05 25.5 0.4 2.1e-05 24.7 0.1 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase AP_endonuc_2 PF01261.24 KFM63159.1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Hydrolase PF00702.26 KFM63159.1 - 0.11 12.8 0.2 0.16 12.2 0.2 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AroM PF07302.11 KFM63159.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 AroM protein Creatinase_N_2 PF16189.5 KFM63160.1 - 3.1e-49 167.2 0.1 6e-49 166.2 0.1 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KFM63160.1 - 3.1e-46 157.7 0.0 4.6e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KFM63160.1 - 1.6e-21 76.1 1.6 2.7e-21 75.4 0.2 2.3 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KFM63160.1 - 8.9e-20 71.7 0.0 1.7e-15 57.8 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain FAM70 PF14967.6 KFM63161.1 - 3.6 7.0 5.3 7.3 6.0 5.3 1.5 1 0 0 1 1 1 0 FAM70 protein Methyltransf_22 PF13383.6 KFM63164.1 - 2.4e-08 33.9 0.2 2.7e-08 33.7 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KFM63164.1 - 8.4e-07 29.2 0.1 1e-06 28.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain MANEC PF07502.14 KFM63166.1 - 8.9e-05 22.7 6.2 0.00016 21.9 6.2 1.4 1 0 0 1 1 1 1 MANEC domain CD20 PF04103.15 KFM63166.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 CD20-like family SAM_1 PF00536.30 KFM63168.1 - 2.8e-33 114.1 0.2 1.1e-16 61.0 0.4 2.9 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM63168.1 - 3e-28 97.7 0.1 1.5e-13 50.6 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Caskin-tail PF16632.5 KFM63168.1 - 0.00022 21.6 0.1 0.0006 20.2 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of Caskin NCD1 PF04904.13 KFM63168.1 - 0.057 13.4 0.0 0.16 12.0 0.0 1.6 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Ank_4 PF13637.6 KFM63169.1 - 4.2e-42 142.0 3.6 1.8e-09 38.0 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM63169.1 - 5.4e-37 126.3 2.2 1.1e-14 54.7 0.2 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM63169.1 - 4.3e-34 116.1 11.2 1e-10 41.6 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFM63169.1 - 1.1e-32 111.0 9.7 5.5e-06 26.6 0.3 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KFM63169.1 - 1e-31 105.4 4.3 5.9e-06 26.2 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat SH3_2 PF07653.17 KFM63169.1 - 6.8e-05 22.5 0.0 0.00016 21.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFM63169.1 - 0.00013 21.8 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM63169.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 SH3 domain DDE_3 PF13358.6 KFM63170.1 - 2.4e-06 27.3 0.0 3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Nterm_IS4 PF13006.7 KFM63170.1 - 0.039 14.1 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Astacin PF01400.24 KFM63171.1 - 7.2e-59 198.6 0.1 8.2e-59 198.4 0.1 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM63171.1 - 0.0012 18.7 0.0 0.052 13.4 0.0 2.7 3 0 0 3 3 3 1 Matrixin Peptidase_M66 PF10462.9 KFM63171.1 - 0.003 16.6 0.8 0.0053 15.8 0.6 1.5 1 1 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 KFM63171.1 - 0.041 14.4 0.4 0.1 13.1 0.1 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4371 PF14291.6 KFM63172.1 - 3.1e-33 115.4 1.1 4.2e-33 115.0 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) bPH_4 PF06713.11 KFM63172.1 - 0.028 14.5 0.0 0.093 12.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial PH domain DUF1216 PF06746.11 KFM63172.1 - 0.071 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) Kp4 PF09044.10 KFM63172.1 - 0.12 12.4 0.7 0.35 10.9 0.3 1.9 1 1 0 2 2 2 0 Kp4 Astacin PF01400.24 KFM63173.1 - 3.9e-07 29.9 0.0 4.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) tRNA_edit PF04073.15 KFM63173.1 - 0.16 12.0 0.0 0.2 11.7 0.0 1.2 1 1 0 1 1 1 0 Aminoacyl-tRNA editing domain Clathrin-link PF09268.10 KFM63173.1 - 0.81 9.1 3.0 21 4.6 0.2 3.5 4 0 0 4 4 4 0 Clathrin, heavy-chain linker Astacin PF01400.24 KFM63174.1 - 7.3e-33 113.8 0.0 8.3e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM63174.1 - 0.013 15.3 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 KFM63174.1 - 0.025 13.5 0.3 0.043 12.8 0.3 1.4 1 1 0 1 1 1 0 Peptidase M66 DUF3810 PF12725.7 KFM63174.1 - 0.17 11.2 0.2 0.25 10.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Astacin PF01400.24 KFM63175.1 - 1.4e-54 184.6 0.0 1.8e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM63175.1 - 0.0037 17.1 0.0 0.089 12.6 0.0 2.2 2 0 0 2 2 2 1 Matrixin Peptidase_M66 PF10462.9 KFM63175.1 - 0.045 12.7 1.5 0.11 11.4 0.9 1.7 1 1 1 2 2 2 0 Peptidase M66 Reprolysin_3 PF13582.6 KFM63175.1 - 0.063 13.8 0.0 0.087 13.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4932 PF16286.5 KFM63175.1 - 0.14 11.4 0.6 1.6 8.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4932) Astacin PF01400.24 KFM63176.1 - 1.5e-54 184.6 0.0 1.8e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM63176.1 - 0.019 14.8 0.1 0.058 13.2 0.2 1.5 1 1 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 KFM63176.1 - 0.13 12.8 0.1 0.2 12.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KFM63176.1 - 0.16 10.9 0.7 0.38 9.6 0.5 1.6 1 1 1 2 2 2 0 Peptidase M66 Peptidase_M8 PF01457.16 KFM63176.1 - 0.18 10.5 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin Astacin PF01400.24 KFM63177.1 - 1.4e-58 197.6 0.0 1.8e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM63177.1 - 0.13 12.1 0.0 0.93 9.3 0.0 2.3 3 0 0 3 3 3 0 Matrixin Astacin PF01400.24 KFM63178.1 - 2e-56 190.6 0.0 2.4e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM63178.1 - 6.4 6.6 6.0 12 5.7 1.5 2.8 2 1 1 3 3 3 0 Matrixin Pinin_SDK_memA PF04696.13 KFM63179.1 - 9.3e-32 109.8 15.2 9.3e-32 109.8 15.2 2.1 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 KFM63179.1 - 0.013 15.8 12.8 0.013 15.8 12.8 2.7 1 1 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif BAH PF01426.18 KFM63179.1 - 0.016 15.0 2.0 0.027 14.3 2.0 1.4 1 0 0 1 1 1 0 BAH domain PGM_PMM_I PF02878.16 KFM63179.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF2247 PF10004.9 KFM63179.1 - 2.4 7.9 11.2 1 9.2 6.4 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) VIR_N PF15912.5 KFM63180.1 - 6.1e-73 245.6 5.3 6.1e-73 245.6 5.3 4.4 1 1 2 3 3 3 1 Virilizer, N-terminal Ras PF00071.22 KFM63181.1 - 2e-40 138.1 1.0 2.3e-40 137.8 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM63181.1 - 1e-27 96.7 0.1 1.6e-27 96.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM63181.1 - 6e-16 58.4 0.3 7.2e-16 58.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM63181.1 - 3.7e-07 30.2 0.3 4.1e-06 26.9 0.3 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM63181.1 - 5.7e-06 25.8 0.2 7.3e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM63181.1 - 4.9e-05 22.8 0.1 7.4e-05 22.2 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFM63181.1 - 5.1e-05 23.2 0.0 0.00033 20.6 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFM63181.1 - 0.0014 18.2 0.3 0.0032 17.0 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KFM63181.1 - 0.012 15.0 0.1 0.034 13.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 KFM63181.1 - 0.044 13.5 0.0 5.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation VCH_CASS14 PF18315.1 KFM63181.1 - 0.056 13.5 0.3 6.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Integron cassette protein VCH_CASS1 chain FeoB_N PF02421.18 KFM63181.1 - 0.089 12.3 0.2 0.45 10.0 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B HTH_Tnp_Tc3_2 PF01498.18 KFM63182.1 - 3.1e-14 53.0 1.0 5.8e-14 52.1 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63182.1 - 1e-13 51.3 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63183.1 - 4.7e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63183.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63183.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63183.1 - 0.0023 17.7 0.6 0.0074 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63183.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 KFM63184.1 - 2.3e-22 78.3 48.1 1.3e-07 31.7 1.1 8.3 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM63184.1 - 1.6e-20 72.0 52.7 0.00017 22.1 0.6 7.9 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM63184.1 - 1.1e-18 66.5 55.1 7.1e-05 23.0 0.9 8.0 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-met PF12874.7 KFM63184.1 - 1.2e-15 57.3 43.3 0.0021 18.4 0.2 7.9 8 0 0 8 8 8 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63184.1 - 6.7e-11 42.2 31.1 0.00081 19.6 0.0 7.9 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM63184.1 - 0.00079 19.4 46.9 0.45 10.6 0.3 7.2 7 0 0 7 7 7 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63184.1 - 0.0077 16.0 0.2 0.0077 16.0 0.2 6.7 8 0 0 8 8 8 2 C2H2-type zinc-finger domain BolA PF01722.18 KFM63184.1 - 0.013 15.8 4.2 2.8 8.3 0.1 3.7 3 0 0 3 3 3 0 BolA-like protein zf-C2H2_2 PF12756.7 KFM63184.1 - 0.026 14.9 36.2 0.2 12.0 2.4 6.8 3 3 3 6 6 6 0 C2H2 type zinc-finger (2 copies) HypA PF01155.19 KFM63184.1 - 0.3 11.1 16.7 1.8 8.6 0.4 4.3 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2 PF00096.26 KFM63185.1 - 0.00073 19.9 1.1 0.0015 18.9 1.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 KFM63185.1 - 0.00077 19.8 1.2 0.0016 18.8 1.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63185.1 - 0.029 14.7 2.9 0.084 13.2 2.9 1.8 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.5 KFM63185.1 - 0.12 11.5 1.3 0.17 11.1 1.3 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_4 PF13894.6 KFM63185.1 - 0.18 12.8 1.2 0.3 12.0 0.7 1.7 1 1 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.15 KFM63185.1 - 0.42 10.7 7.3 0.94 9.6 6.5 1.9 1 1 1 2 2 2 0 BED zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM63186.1 - 1.9e-16 60.1 2.2 4.3e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63186.1 - 9.1e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63187.1 - 3.6e-16 59.2 3.0 6.3e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63187.1 - 1.4e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63187.1 - 2.5e-07 30.4 1.6 7.6e-07 28.8 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63187.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63187.1 - 2.5 8.8 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DUF4371 PF14291.6 KFM63188.1 - 1.1e-09 38.3 0.0 2.6e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) DDE_3 PF13358.6 KFM63188.1 - 0.029 14.1 0.0 0.11 12.3 0.0 2.0 1 0 0 1 1 1 0 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.14 KFM63188.1 - 0.029 14.1 0.7 0.087 12.6 0.0 2.1 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region PQ-loop PF04193.14 KFM63189.1 - 2.1e-28 97.8 6.1 1.1e-14 54.0 0.0 2.7 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KFM63189.1 - 0.023 15.5 8.1 2.7 8.8 0.1 2.6 2 1 0 2 2 2 0 ER lumen protein retaining receptor MRP-S22 PF10245.9 KFM63190.1 - 1.2e-95 319.8 2.2 1.5e-95 319.6 2.2 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 Methyltransf_25 PF13649.6 KFM63191.1 - 0.00026 21.6 0.0 0.00076 20.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF2703 PF10865.8 KFM63191.1 - 0.0017 18.6 0.1 0.015 15.5 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2703) DUF43 PF01861.16 KFM63191.1 - 0.0089 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain DOT1 PF08123.13 KFM63191.1 - 0.014 15.0 0.7 0.17 11.4 0.7 2.2 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_18 PF12847.7 KFM63191.1 - 0.021 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 KFM63191.1 - 0.056 13.0 0.1 0.097 12.2 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase OPA3 PF07047.12 KFM63192.1 - 1e-42 144.8 0.2 1.3e-42 144.5 0.2 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Phi-29_GP16_7 PF06720.11 KFM63192.1 - 0.056 13.3 0.1 0.089 12.6 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 SlyX PF04102.12 KFM63192.1 - 0.086 13.5 0.6 0.18 12.5 0.6 1.6 1 0 0 1 1 1 0 SlyX WD-3 PF09765.9 KFM63193.1 - 7.9e-73 245.3 1.3 9.1e-73 245.1 1.3 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 KFM63193.1 - 4.5e-24 84.4 8.2 1.1e-23 83.2 8.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KFM63193.1 - 0.00089 19.5 1.1 0.0021 18.3 1.1 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KFM63193.1 - 0.0016 18.7 6.9 0.0017 18.6 4.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING-like PF08746.11 KFM63193.1 - 0.027 14.8 5.6 0.029 14.7 0.9 2.6 2 0 0 2 2 2 0 RING-like domain zf-C2H2_11 PF16622.5 KFM63193.1 - 0.082 12.7 1.3 0.17 11.6 1.3 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type PHD PF00628.29 KFM63193.1 - 0.092 12.7 6.2 0.38 10.7 3.7 2.5 2 0 0 2 2 2 0 PHD-finger P22_AR_C PF10548.9 KFM63193.1 - 0.26 11.5 1.4 56 4.0 0.1 3.8 4 1 1 5 5 5 0 P22AR C-terminal domain Cofilin_ADF PF00241.20 KFM63194.1 - 4.9e-22 78.0 0.0 5.5e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein T6SS_VipA PF05591.12 KFM63194.1 - 0.091 12.6 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 Peptidase_M17 PF00883.21 KFM63195.1 - 9.4e-97 324.0 0.3 1.1e-96 323.8 0.3 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain ABC2_membrane_6 PF06182.11 KFM63195.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein COX8 PF02285.15 KFM63196.1 - 3e-07 30.2 0.1 5.2e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIII DHHC PF01529.20 KFM63197.1 - 0.0001 22.4 0.6 0.0001 22.4 0.6 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase BRICHOS PF04089.14 KFM63198.1 - 2.8e-06 27.5 0.0 1.3e-05 25.3 0.0 2.2 1 0 0 1 1 1 1 BRICHOS domain HTH_Tnp_Tc3_2 PF01498.18 KFM63199.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63199.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63199.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63199.1 - 0.0027 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63199.1 - 2.1 9.0 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DUF4227 PF14004.6 KFM63201.1 - 0.1 12.6 1.6 3.6 7.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4227) HTH_Tnp_Tc3_2 PF01498.18 KFM63202.1 - 2.3e-16 59.8 4.4 5.7e-16 58.5 2.2 2.5 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM63202.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63202.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63202.1 - 0.0027 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63202.1 - 1.8 9.2 15.6 0.12 13.0 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain UCH PF00443.29 KFM63203.1 - 1.8e-47 162.0 0.6 2.1e-47 161.8 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM63203.1 - 7.2e-19 68.5 7.4 1.2e-17 64.5 7.4 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFM63203.1 - 0.0011 18.5 10.0 0.0071 15.9 0.1 3.5 3 1 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase eIF2A PF08662.11 KFM63204.1 - 3e-59 200.2 10.9 2e-55 187.7 1.7 3.7 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KFM63204.1 - 4.8e-10 39.1 0.1 1.2e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 KFM63204.1 - 0.00072 19.8 0.1 18 5.7 0.0 4.7 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM63204.1 - 0.0015 19.3 5.1 3.3 8.7 0.0 4.6 3 1 1 4 4 4 1 WD domain, G-beta repeat KH_9 PF17904.1 KFM63204.1 - 0.09 13.2 0.7 0.23 11.9 0.7 1.6 1 0 0 1 1 1 0 FMRP KH0 domain 14-3-3 PF00244.20 KFM63204.1 - 0.43 10.1 3.7 0.71 9.3 3.7 1.2 1 0 0 1 1 1 0 14-3-3 protein Colicin_V PF02674.16 KFM63205.1 - 0.0013 18.7 0.4 0.0018 18.2 0.4 1.2 1 0 0 1 1 1 1 Colicin V production protein p450 PF00067.22 KFM63207.1 - 7.2e-94 315.1 0.2 9.2e-94 314.8 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.27 KFM63209.1 - 1.1e-16 61.0 0.0 2.6e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 KFM63209.1 - 2e-06 27.9 0.2 3.1e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 Pao retrotransposon peptidase RNase_J_C PF17770.1 KFM63209.1 - 0.012 16.7 0.8 0.012 16.7 0.8 2.5 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain ATP-synt_ab_N PF02874.23 KFM63210.1 - 1.9e-13 50.7 0.1 3e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HTH_Tnp_Tc3_2 PF01498.18 KFM63210.1 - 0.00043 20.5 0.0 0.0018 18.5 0.0 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 KFM63210.1 - 0.003 17.5 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix MarR_2 PF12802.7 KFM63210.1 - 0.0058 16.5 0.0 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 MarR family ATP-synt_ab PF00006.25 KFM63211.1 - 2.9e-63 213.4 0.0 3.7e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KFM63211.1 - 0.0024 17.1 0.9 0.005 16.1 0.2 1.8 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 KFM63211.1 - 0.0025 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KFM63211.1 - 0.013 15.5 0.3 0.029 14.3 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KFM63211.1 - 0.024 15.0 0.1 0.073 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KFM63211.1 - 0.031 14.7 0.1 0.86 10.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KFM63211.1 - 0.06 12.6 0.1 0.14 11.4 0.1 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KFM63211.1 - 0.06 13.7 0.7 0.21 11.9 0.2 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM63211.1 - 0.063 13.8 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 ABC transporter T3SS_ATPase_C PF18269.1 KFM63211.1 - 0.1 12.5 0.5 0.81 9.6 0.5 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain SPESP1 PF15754.5 KFM63213.1 - 0.0033 16.7 0.1 0.0056 15.9 0.1 1.3 1 0 0 1 1 1 1 Sperm equatorial segment protein 1 Trypan_PARP PF05887.11 KFM63213.1 - 0.033 14.2 10.7 0.06 13.3 3.0 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) GDNF PF02351.16 KFM63217.1 - 2.9e-05 24.9 28.4 0.00017 22.5 8.7 2.6 2 0 0 2 2 2 2 GDNF/GAS1 domain PhzC-PhzF PF02567.16 KFM63218.1 - 3.2e-27 95.7 0.1 3.8e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAP_epimerase PF01678.19 KFM63218.1 - 0.0015 18.7 0.0 0.0031 17.7 0.0 1.6 1 1 0 1 1 1 1 Diaminopimelate epimerase PhzC-PhzF PF02567.16 KFM63219.1 - 1.5e-19 70.6 0.0 1.6e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein RVT_1 PF00078.27 KFM63222.1 - 2.1e-14 53.6 0.0 2.2e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 KFM63223.1 - 3.2e-23 82.4 1.0 4.3e-23 82.0 1.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HTH_Tnp_Tc3_2 PF01498.18 KFM63225.1 - 5.3e-16 58.6 6.5 8.2e-16 58.0 6.5 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63225.1 - 0.00042 20.9 1.5 0.00042 20.9 1.5 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63225.1 - 0.0077 16.0 2.1 0.074 12.9 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63225.1 - 0.011 15.8 0.1 0.041 14.0 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM63225.1 - 0.033 14.2 1.0 0.033 14.2 1.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM63225.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KFM63226.1 - 4.9e-16 58.7 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63226.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63226.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63226.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63226.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain FAM176 PF14851.6 KFM63228.1 - 0.04 13.6 3.9 0.043 13.5 3.9 1.1 1 0 0 1 1 1 0 FAM176 family Rtf2 PF04641.12 KFM63228.1 - 0.16 11.3 8.2 0.17 11.2 8.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Dynactin_p62 PF05502.13 KFM63228.1 - 0.22 10.2 5.7 0.26 10.0 5.7 1.0 1 0 0 1 1 1 0 Dynactin p62 family LicD PF04991.13 KFM63228.1 - 0.63 10.1 5.6 0.72 9.9 5.6 1.0 1 0 0 1 1 1 0 LicD family DUF1754 PF08555.10 KFM63228.1 - 2.1 9.2 16.5 3.1 8.7 16.5 1.4 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Presenilin PF01080.17 KFM63228.1 - 3.6 6.2 4.2 3.4 6.3 4.2 1.0 1 0 0 1 1 1 0 Presenilin OAD_gamma PF04277.13 KFM63228.1 - 5.6 7.6 5.1 6.8 7.4 2.5 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-H2C2_2 PF13465.6 KFM63229.1 - 1.4e-60 199.2 82.5 1.9e-09 37.5 0.8 13.8 13 1 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63229.1 - 8.3e-54 177.2 103.0 8.7e-05 22.8 1.6 11.7 12 1 0 12 12 11 11 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM63229.1 - 4.5e-39 131.7 71.2 2.2e-05 24.3 0.2 11.2 11 0 0 11 11 11 9 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFM63229.1 - 9.2e-35 116.3 88.0 0.0033 18.1 0.9 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM63229.1 - 3.9e-26 90.6 84.0 8.9e-05 22.7 0.7 11.2 11 0 0 11 11 11 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63229.1 - 7.4e-14 51.6 61.0 0.014 15.7 0.6 11.1 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFM63229.1 - 7.3e-11 42.2 47.7 0.018 15.3 3.5 6.1 3 2 3 6 6 6 4 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFM63229.1 - 4.2e-06 26.4 66.8 0.24 11.2 0.6 11.3 11 0 0 11 11 11 5 C2H2-type zinc-finger domain DUF2256 PF10013.9 KFM63229.1 - 4.2e-06 26.8 38.6 4.2 7.6 0.1 10.9 11 0 0 11 11 11 1 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM63229.1 - 0.0012 18.8 38.5 0.42 10.6 0.9 7.3 5 2 2 7 7 7 3 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 KFM63229.1 - 0.0024 18.0 36.0 2.3 8.4 0.9 8.1 5 3 3 8 8 8 3 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM63229.1 - 0.0087 16.8 46.2 0.57 11.0 1.9 6.0 2 1 4 6 6 6 3 zinc-ribbon family zf-MYST PF17772.1 KFM63229.1 - 0.0094 15.5 44.2 0.85 9.3 0.3 9.6 6 3 4 10 10 10 2 MYST family zinc finger domain DUF3268 PF11672.8 KFM63229.1 - 0.011 16.1 27.3 0.48 10.7 0.6 5.4 4 1 2 6 6 6 0 zinc-finger-containing domain Ring_hydroxyl_B PF00866.18 KFM63229.1 - 0.013 15.6 1.0 0.33 11.0 0.0 3.0 3 1 0 3 3 3 0 Ring hydroxylating beta subunit zf-RRPl_C4 PF17026.5 KFM63229.1 - 0.027 14.6 46.5 0.71 10.0 3.7 5.3 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_1 PF14446.6 KFM63229.1 - 0.046 13.7 38.7 10 6.1 0.0 10.1 10 1 0 10 10 10 0 Prokaryotic RING finger family 1 zf-BED PF02892.15 KFM63229.1 - 0.048 13.7 78.0 0.39 10.8 6.2 10.7 3 3 8 11 11 11 0 BED zinc finger DZR PF12773.7 KFM63229.1 - 0.091 12.8 41.0 14 5.8 1.0 6.4 2 2 0 3 3 2 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 KFM63229.1 - 0.11 12.6 42.9 17 5.6 0.2 9.6 9 2 1 10 10 10 0 Sec23/Sec24 zinc finger SKA2 PF16740.5 KFM63229.1 - 0.12 12.1 4.9 3.8 7.3 0.2 4.1 2 1 3 5 5 5 0 Spindle and kinetochore-associated protein 2 zf_UBZ PF18439.1 KFM63229.1 - 0.18 11.4 42.9 1.7 8.3 0.1 9.6 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM63229.1 - 0.24 11.8 76.3 1.6 9.1 4.2 9.3 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) DUF4806 PF16064.5 KFM63229.1 - 1 9.7 4.3 63 4.0 0.1 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4806) Rpr2 PF04032.16 KFM63229.1 - 1.5 9.2 53.1 16 5.8 0.3 7.3 1 1 5 6 6 5 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_11 PF17123.5 KFM63229.1 - 1.8 8.3 20.7 36 4.2 0.1 7.7 8 0 0 8 8 8 0 RING-like zinc finger zf-Paramyx-P PF13008.7 KFM63229.1 - 3.6 7.1 18.4 47 3.6 0.1 6.8 6 1 1 7 7 7 0 Zinc-binding domain of Paramyxoviridae V protein XPA_N PF01286.18 KFM63229.1 - 3.6 7.7 36.8 63 3.7 0.1 10.5 11 0 0 11 11 11 0 XPA protein N-terminal zf-C2H2_3rep PF18868.1 KFM63229.1 - 4.7 7.9 43.0 0.6 10.8 1.6 7.2 3 2 2 5 5 4 0 Zinc finger C2H2-type, 3 repeats HTH_Tnp_Tc3_2 PF01498.18 KFM63230.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63230.1 - 1.3e-13 50.9 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63230.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63230.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63230.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Sedlin_N PF04628.13 KFM63231.1 - 1.9e-40 138.0 2.7 2.1e-40 137.9 2.7 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFM63231.1 - 0.0013 18.7 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 Sybindin-like family FKBP_C PF00254.28 KFM63232.1 - 1.7e-22 79.5 0.0 2.6e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GalKase_gal_bdg PF10509.9 KFM63233.1 - 6.2e-20 70.5 0.2 2.8e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KFM63233.1 - 4.5e-13 49.2 0.2 1e-12 48.1 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFM63233.1 - 2e-10 40.9 0.0 3.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal DUF1972 PF09314.11 KFM63233.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) Dimer_Tnp_hAT PF05699.14 KFM63234.1 - 2e-14 53.1 0.0 6.3e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KFM63234.1 - 3.3e-10 39.8 1.2 3.3e-10 39.8 1.2 2.6 3 0 0 3 3 3 1 BED zinc finger DUF4413 PF14372.6 KFM63234.1 - 6.9e-06 26.4 3.2 0.0013 19.1 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4413) DUF5446 PF17522.2 KFM63234.1 - 1.3 9.2 6.7 0.9 9.8 0.3 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5446) HTH_Tnp_Tc3_2 PF01498.18 KFM63235.1 - 2.2e-16 59.9 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63235.1 - 9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM63236.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Ins_P5_2-kin PF06090.12 KFM63238.1 - 2.1e-06 27.4 0.1 2.3e-06 27.3 0.1 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Ins_P5_2-kin PF06090.12 KFM63239.1 - 4.4e-36 125.0 0.4 5.1e-36 124.8 0.4 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Ins_P5_2-kin PF06090.12 KFM63240.1 - 0.0023 17.4 0.0 0.0024 17.4 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Tnp_P_element PF12017.8 KFM63243.1 - 3.1e-05 23.5 4.1 3.2e-05 23.5 0.0 2.4 1 1 1 3 3 3 1 Transposase protein DUF5572 PF17733.1 KFM63243.1 - 0.0054 16.5 0.5 0.037 13.8 0.2 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5572) MRP-L51 PF10244.9 KFM63243.1 - 0.15 12.3 1.4 1.4 9.1 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit HARE-HTH PF05066.13 KFM63243.1 - 0.21 12.0 1.7 0.66 10.4 0.1 2.2 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain Nse4_C PF08743.10 KFM63243.1 - 0.89 9.9 6.7 2.2 8.6 1.6 2.3 1 1 1 2 2 2 0 Nse4 C-terminal THAP PF05485.12 KFM63244.1 - 5.7e-17 62.4 0.8 8.6e-17 61.8 0.8 1.3 1 0 0 1 1 1 1 THAP domain zf-C3HC4_2 PF13923.6 KFM63245.1 - 1.6e-10 40.7 14.4 2.4e-10 40.1 10.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM63245.1 - 4.7e-09 36.0 10.1 4.7e-09 36.0 10.1 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM63245.1 - 1.6e-07 31.2 12.7 2.7e-07 30.5 3.2 3.6 2 1 1 3 3 3 1 RING-type zinc-finger SAP PF02037.27 KFM63245.1 - 1.1e-06 28.2 0.8 1.1e-06 28.2 0.8 2.2 2 0 0 2 2 2 1 SAP domain zf-C3HC4_3 PF13920.6 KFM63245.1 - 2e-06 27.6 8.1 2e-06 27.6 8.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM63245.1 - 4.9e-06 26.8 10.2 4.9e-06 26.8 10.2 3.1 3 1 0 3 3 3 1 Ring finger domain zf-RING_6 PF14835.6 KFM63245.1 - 7.7e-06 25.7 6.3 4.2e-05 23.3 2.6 2.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KFM63245.1 - 9.9e-06 25.4 12.3 9.9e-06 25.4 12.3 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-WRNIP1_ubi PF18279.1 KFM63245.1 - 2.8e-05 24.4 1.0 0.0023 18.4 0.0 2.8 2 0 0 2 2 2 1 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C3HC4_4 PF15227.6 KFM63245.1 - 0.00028 21.0 9.4 0.00028 21.0 9.4 3.3 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFM63245.1 - 0.0017 18.4 5.9 0.0017 18.4 5.9 3.5 4 1 0 4 4 4 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFM63245.1 - 0.0088 16.3 7.3 0.0088 16.3 7.3 3.6 3 2 0 3 3 3 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFM63245.1 - 0.043 13.7 15.5 0.21 11.5 7.0 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 KFM63245.1 - 6.8 7.1 10.0 2.8 8.3 0.2 3.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cyt-b5 PF00173.28 KFM63246.1 - 6.7e-15 55.0 0.1 9.4e-15 54.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SLIDE PF09111.10 KFM63247.1 - 7.8e-44 148.3 1.9 7.8e-44 148.3 1.9 2.1 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 KFM63247.1 - 1.2e-31 109.7 0.5 1.2e-31 109.7 0.5 3.3 4 1 0 4 4 4 1 HAND Myb_DNA-binding PF00249.31 KFM63247.1 - 9.2e-07 29.0 0.2 0.04 14.1 0.0 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain DUF1086 PF06461.11 KFM63247.1 - 0.013 15.4 0.1 0.034 14.0 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) DUF1456 PF07308.13 KFM63247.1 - 0.017 15.4 0.1 0.052 13.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) DUF4800 PF16057.5 KFM63247.1 - 0.038 13.3 0.6 0.074 12.3 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) KIP1 PF07765.12 KFM63247.1 - 0.04 14.0 0.2 0.15 12.2 0.2 2.0 1 0 0 1 1 1 0 KIP1-like protein CDH1_2_SANT_HL1 PF18375.1 KFM63247.1 - 0.4 11.4 3.2 5.6 7.7 0.4 2.7 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 SNF2_N PF00176.23 KFM63248.1 - 1.7e-79 267.1 0.4 4e-79 265.9 0.4 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM63248.1 - 5.8e-23 81.4 0.0 6e-22 78.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM63248.1 - 1.9e-11 44.2 0.0 7.8e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM63248.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 KFM63248.1 - 8.5e-06 26.2 0.3 8.5e-06 26.2 0.3 2.0 2 0 0 2 2 2 1 DNA-binding domain HDA2-3 PF11496.8 KFM63248.1 - 9.3e-05 21.7 0.0 0.00021 20.6 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KFM63248.1 - 0.00085 19.0 0.0 0.0019 17.9 0.0 1.6 1 1 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KFM63248.1 - 0.0079 15.4 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_14 PF13173.6 KFM63248.1 - 0.12 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain HTH_Tnp_Tc3_2 PF01498.18 KFM63251.1 - 5.1e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63251.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63251.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63251.1 - 0.0027 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63251.1 - 0.026 14.7 0.4 0.093 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM63251.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain 7tm_1 PF00001.21 KFM63252.1 - 3.3e-43 147.9 21.0 4.1e-43 147.6 21.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM63252.1 - 1.5e-08 34.6 15.0 1.5e-08 34.6 15.0 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KFM63252.1 - 8e-06 25.4 14.2 4.3e-05 22.9 14.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw OTOS PF15182.6 KFM63252.1 - 0.086 12.8 0.4 0.16 11.9 0.4 1.3 1 0 0 1 1 1 0 Otospiralin Serpentine_r_xa PF03383.15 KFM63252.1 - 1.8 8.5 13.5 0.081 12.9 4.3 2.3 1 1 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa DUF4604 PF15377.6 KFM63254.1 - 3.9e-12 46.9 2.4 4.2e-12 46.8 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF3349 PF11829.8 KFM63254.1 - 0.013 16.2 0.2 0.019 15.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) PDDEXK_4 PF14281.6 KFM63254.1 - 0.021 15.0 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily HA2 PF04408.23 KFM63256.1 - 4.1e-17 62.4 2.5 4.4e-17 62.3 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFM63256.1 - 1.4e-13 51.1 0.0 3.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM63256.1 - 2.7e-06 27.2 0.3 1.6e-05 24.7 0.3 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFM63256.1 - 0.00052 20.3 0.2 0.012 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFM63256.1 - 0.0062 16.9 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFM63256.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF5081 PF16887.5 KFM63256.1 - 0.026 13.6 0.3 0.19 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5081) Rad17 PF03215.15 KFM63256.1 - 0.065 13.1 0.1 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain OB_NTP_bind PF07717.16 KFM63256.1 - 0.079 13.3 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold ATPase PF06745.13 KFM63256.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Reprolysin_3 PF13582.6 KFM63257.1 - 1.5e-16 61.0 0.0 3.8e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KFM63257.1 - 2.5e-12 47.1 0.0 1.5e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFM63257.1 - 1.9e-11 44.3 7.1 4.1e-11 43.2 7.1 1.6 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin_2 PF13574.6 KFM63257.1 - 1.2e-08 35.1 0.1 2.1e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM63257.1 - 7e-08 32.9 0.0 2.3e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFM63257.1 - 2.7e-07 30.4 0.0 4.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KFM63257.1 - 0.00093 19.4 0.1 0.0037 17.5 0.0 2.0 2 0 0 2 2 2 1 Reprolysin family propeptide Peptidase_M10 PF00413.24 KFM63257.1 - 0.0085 15.9 0.0 0.013 15.3 0.0 1.4 1 1 0 1 1 1 1 Matrixin HTH_Tnp_Tc3_2 PF01498.18 KFM63259.1 - 1.9e-08 34.4 0.0 2e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Transposase zf-RING_2 PF13639.6 KFM63262.1 - 7.6e-08 32.6 9.7 1.2e-07 32.0 9.7 1.3 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KFM63262.1 - 2.5e-05 24.4 8.7 2.5e-05 24.4 8.7 2.1 2 1 0 2 2 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KFM63262.1 - 0.00022 21.2 5.2 0.00032 20.7 5.2 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFM63262.1 - 0.0003 21.0 9.9 0.00084 19.6 9.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 KFM63262.1 - 0.00052 20.1 5.3 0.0011 19.1 5.3 1.6 1 1 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 KFM63262.1 - 0.014 15.0 7.7 0.066 12.8 7.7 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KFM63262.1 - 0.023 14.6 7.5 0.042 13.8 7.5 1.5 1 0 0 1 1 1 0 PHD-finger DUF4085 PF13315.6 KFM63262.1 - 0.038 13.6 0.0 0.049 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) zf-C3HC4 PF00097.25 KFM63262.1 - 0.04 13.8 10.0 0.14 12.1 10.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM63262.1 - 0.045 13.6 10.7 0.11 12.4 10.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM63262.1 - 0.05 13.5 8.7 2.8 7.9 8.7 2.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KFM63262.1 - 0.07 13.5 9.1 0.16 12.3 9.1 1.6 1 1 0 1 1 1 0 RING-like domain Zf_RING PF16744.5 KFM63262.1 - 0.19 11.9 8.3 0.3 11.2 6.2 2.3 1 1 1 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 KFM63262.1 - 0.36 10.9 9.8 1.7 8.8 0.1 2.7 1 1 1 2 2 2 0 PHD-finger zf-H2C2_2 PF13465.6 KFM63262.1 - 0.37 11.3 7.8 2.6 8.6 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING_4 PF14570.6 KFM63262.1 - 0.37 10.6 7.9 2.5 8.0 5.0 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain C1_1 PF00130.22 KFM63262.1 - 0.53 10.2 9.7 0.073 13.0 5.2 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_4 PF14447.6 KFM63262.1 - 0.96 9.4 8.0 0.5 10.3 0.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 KFM63262.1 - 1.3 9.4 5.6 8.7 6.7 5.6 2.2 1 1 0 1 1 1 0 zinc-ribbon IBR PF01485.21 KFM63262.1 - 1.8 8.8 8.2 8.4 6.7 8.2 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain SH3_9 PF14604.6 KFM63263.1 - 3e-28 97.4 4.4 4.5e-09 36.0 0.2 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFM63263.1 - 9.7e-25 85.9 2.2 1.1e-09 37.8 0.1 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KFM63263.1 - 4.3e-21 74.3 0.1 3.9e-08 32.9 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 KFM63263.1 - 4.5e-06 26.8 5.6 0.0092 16.2 0.0 2.8 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_16 PF18348.1 KFM63263.1 - 0.0029 17.4 1.4 1.1 9.1 0.1 3.1 3 0 0 3 3 3 2 Bacterial dipeptidyl-peptidase Sh3 domain hSH3 PF14603.6 KFM63263.1 - 0.0031 17.9 0.0 1.6 9.2 0.0 3.1 3 0 0 3 3 3 1 Helically-extended SH3 domain SH3_10 PF17902.1 KFM63263.1 - 0.0046 17.0 0.0 0.033 14.3 0.0 2.2 2 0 0 2 2 2 1 SH3 domain DUF4889 PF16230.5 KFM63263.1 - 0.012 15.8 0.0 1.8 8.9 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4889) SH3_4 PF06347.13 KFM63263.1 - 0.014 15.2 0.2 2.8 7.8 0.1 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain 60KD_IMP PF02096.20 KFM63264.1 - 1.2e-12 48.0 0.4 2.8e-12 46.8 0.4 1.5 1 1 0 1 1 1 1 60Kd inner membrane protein DDE_3 PF13358.6 KFM63265.1 - 0.00023 20.9 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease ANF_receptor PF01094.28 KFM63266.1 - 1.7e-16 60.3 0.0 2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KFM63266.1 - 0.0025 17.5 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein PIF1 PF05970.14 KFM63267.1 - 2.1e-27 96.2 0.0 3.2e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Pox_RNA_Pol_22 PF05273.13 KFM63267.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus RNA polymerase 22 kDa subunit DUF3019 PF11456.8 KFM63267.1 - 4.7 7.8 7.7 6.1 7.4 3.9 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3019) DDE_3 PF13358.6 KFM63268.1 - 1.5e-11 44.3 0.0 2.8e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_92 PF01697.27 KFM63268.1 - 0.072 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 HTH_Tnp_Tc3_2 PF01498.18 KFM63269.1 - 4.8e-16 58.8 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63269.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63269.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63269.1 - 0.0027 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63269.1 - 0.023 14.8 0.4 0.09 12.9 0.4 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM63269.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Y_phosphatase PF00102.27 KFM63270.1 - 4.8e-134 445.2 3.2 1.4e-85 286.6 2.8 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFM63270.1 - 1.1e-44 150.6 4.0 1.9e-14 53.7 0.0 4.7 4 0 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM63270.1 - 2e-07 31.4 0.3 1.8 9.2 0.0 4.7 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain PTPlike_phytase PF14566.6 KFM63270.1 - 0.00051 20.2 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 KFM63270.1 - 0.00059 19.7 0.0 0.0022 17.8 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM63270.1 - 0.0091 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Actin PF00022.19 KFM63271.1 - 2.3e-55 187.9 0.0 2.2e-53 181.3 0.0 2.8 2 1 0 2 2 2 1 Actin PH PF00169.29 KFM63271.1 - 1.5e-06 28.7 0.1 1.5e-06 28.7 0.1 2.9 3 0 0 3 3 3 1 PH domain zf-AD PF07776.15 KFM63271.1 - 0.052 13.8 2.7 0.21 11.9 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) HSBP1 PF06825.12 KFM63271.1 - 0.091 12.6 1.0 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 PH_17 PF18012.1 KFM63271.1 - 0.11 12.3 0.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 PH domain WBP-1 PF11669.8 KFM63272.1 - 0.2 12.3 3.9 0.3 11.7 2.0 2.2 1 1 1 2 2 2 0 WW domain-binding protein 1 Dickkopf_N PF04706.12 KFM63273.1 - 0.016 15.7 4.1 0.02 15.4 4.1 1.1 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region HTH_Tnp_Tc3_2 PF01498.18 KFM63275.1 - 2.2e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63275.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DSPc PF00782.20 KFM63276.1 - 2.1e-09 37.3 0.2 2.8e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4326 PF14216.6 KFM63276.1 - 0.017 15.8 0.8 0.021 15.5 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4326) DDE_3 PF13358.6 KFM63277.1 - 4.2e-16 59.0 0.1 5.6e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63277.1 - 7.7e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63277.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63277.1 - 0.0024 17.6 0.1 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63277.1 - 0.014 15.5 0.1 0.064 13.4 0.1 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM63277.1 - 0.035 14.1 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM63279.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63279.1 - 9e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Fcf1 PF04900.12 KFM63284.1 - 2e-06 28.1 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KFM63284.1 - 0.0003 21.1 0.1 0.00062 20.1 0.0 1.5 2 0 0 2 2 2 1 PIN like domain COBRA1 PF06209.13 KFM63285.1 - 5.5e-217 721.2 5.8 6.5e-217 721.0 5.8 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) DUF664 PF04978.12 KFM63285.1 - 0.061 13.7 0.1 0.16 12.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF664) zf-C2H2 PF00096.26 KFM63288.1 - 5.1e-17 61.3 14.3 3.9e-06 27.0 1.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM63288.1 - 1.8e-13 50.2 18.1 5.5e-08 32.9 0.5 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM63288.1 - 2.1e-11 43.6 14.9 0.00034 21.2 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM63288.1 - 0.0002 21.3 10.6 0.0075 16.2 1.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFM63288.1 - 0.00079 20.0 4.1 0.017 15.7 1.4 2.8 1 1 2 3 3 3 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFM63288.1 - 0.0023 18.2 2.9 0.0081 16.4 2.9 1.9 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 KFM63288.1 - 0.015 16.0 0.9 0.72 10.5 0.2 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KFM63288.1 - 0.023 15.0 4.9 1.2 9.5 0.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFM63288.1 - 0.14 12.1 0.2 0.14 12.1 0.2 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFM63288.1 - 0.2 12.0 3.3 14 6.1 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding IBR PF01485.21 KFM63288.1 - 0.46 10.7 7.5 0.15 12.3 3.1 2.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-met PF12874.7 KFM63288.1 - 1 9.8 6.3 0.82 10.2 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Retrotran_gag_2 PF14223.6 KFM63289.1 - 3.5e-08 33.2 0.1 4.9e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ATP-synt PF00231.19 KFM63290.1 - 3e-48 164.9 1.2 3.6e-48 164.7 1.2 1.0 1 0 0 1 1 1 1 ATP synthase Fasciclin PF02469.22 KFM63291.1 - 3.6e-23 82.2 0.0 5.5e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 Fasciclin domain DDE_3 PF13358.6 KFM63293.1 - 3e-15 56.2 0.1 1.5e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63293.1 - 1.7e-05 25.0 0.6 3.4e-05 24.0 0.6 1.5 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 KFM63293.1 - 0.94 9.3 4.4 0.98 9.2 0.1 2.9 4 0 0 4 4 4 0 Helix-turn-helix domain EGF PF00008.27 KFM63294.1 - 1.7e-49 165.7 147.8 1.9e-08 34.5 7.5 11.4 10 1 0 10 10 10 8 EGF-like domain hEGF PF12661.7 KFM63294.1 - 1e-27 95.8 131.4 4.9e-06 27.0 4.3 12.3 12 0 0 12 12 10 7 Human growth factor-like EGF MNNL PF07657.13 KFM63294.1 - 2e-27 95.0 0.5 2e-27 95.0 0.5 5.6 5 1 1 6 6 2 1 N terminus of Notch ligand DSL PF01414.19 KFM63294.1 - 4.9e-24 84.4 8.8 4.9e-24 84.4 8.8 8.7 3 1 6 9 9 8 1 Delta serrate ligand EGF_2 PF07974.13 KFM63294.1 - 3.8e-10 39.9 188.9 0.01 16.2 9.7 12.4 12 0 0 12 12 11 8 EGF-like domain Ly49 PF08391.10 KFM63294.1 - 0.00089 19.6 0.8 0.0018 18.6 0.8 1.5 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region EGF_CA PF07645.15 KFM63294.1 - 0.0021 18.2 33.6 0.0026 17.9 15.6 11.4 5 3 4 10 10 9 4 Calcium-binding EGF domain GAPT PF11770.8 KFM63294.1 - 0.0026 17.7 0.1 0.0044 16.9 0.1 1.3 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) TMEM51 PF15345.6 KFM63294.1 - 0.012 15.4 0.2 0.02 14.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3180 PF11377.8 KFM63294.1 - 0.014 15.6 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) TMEM154 PF15102.6 KFM63294.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KFM63294.1 - 0.056 14.3 0.0 0.14 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PAP_PilO PF06864.12 KFM63294.1 - 0.091 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) p450 PF00067.22 KFM63295.1 - 4.3e-25 88.4 0.6 4.9e-25 88.2 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 HEPN_SAV2148 PF18725.1 KFM63295.1 - 0.0084 15.5 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 SAV2148-like HEPN DDE_3 PF13358.6 KFM63296.1 - 0.0018 18.1 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM63297.1 - 1.1e-10 41.4 0.0 1.2e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Cyt-b5 PF00173.28 KFM63298.1 - 1.7e-08 34.5 0.1 3.5e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MutS_I PF01624.20 KFM63299.1 - 1.1e-29 103.0 0.1 2.6e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 KFM63300.1 - 1.5e-23 84.1 0.2 3e-23 83.0 0.2 1.6 1 1 0 1 1 1 1 MutS domain III Cbl_N PF02262.16 KFM63300.1 - 0.0022 18.0 1.1 0.0048 16.9 0.1 2.0 2 0 0 2 2 2 1 CBL proto-oncogene N-terminal domain 1 MutS_IV PF05190.18 KFM63300.1 - 0.015 15.6 0.0 0.089 13.2 0.0 2.3 2 0 0 2 2 2 0 MutS family domain IV DUF2768 PF10966.8 KFM63300.1 - 0.044 14.2 0.6 0.092 13.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) RACo_linker PF17650.1 KFM63300.1 - 0.071 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 RACo linker region MutS_V PF00488.21 KFM63301.1 - 9.4e-70 234.5 0.2 1.1e-69 234.2 0.2 1.0 1 0 0 1 1 1 1 MutS domain V AAA_14 PF13173.6 KFM63301.1 - 0.05 13.6 0.0 0.2 11.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFM63301.1 - 0.085 13.3 0.0 0.22 11.9 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_12 PF13087.6 KFM63302.1 - 8e-61 205.1 0.0 1.5e-60 204.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM63302.1 - 2.1e-47 162.1 1.8 2.6e-25 89.7 0.1 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KFM63302.1 - 5.6e-33 113.0 0.0 1e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KFM63302.1 - 3.2e-13 49.8 0.1 7.4e-12 45.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFM63302.1 - 4.4e-11 43.3 0.1 2.5e-10 40.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KFM63302.1 - 1.6e-05 24.4 0.2 0.0014 17.9 0.0 2.9 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFM63302.1 - 3.5e-05 23.9 0.0 7.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KFM63302.1 - 0.00025 20.9 0.0 0.00075 19.4 0.0 1.9 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KFM63302.1 - 0.0053 16.3 0.0 0.065 12.7 0.0 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 KFM63302.1 - 0.0089 15.2 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase Viral_helicase1 PF01443.18 KFM63302.1 - 0.013 15.2 0.1 2.9 7.5 0.0 3.3 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 KFM63302.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 KFM63302.1 - 0.046 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 KFM63302.1 - 0.09 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 KFM63302.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 KFM63302.1 - 0.13 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFM63302.1 - 0.14 11.7 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFM63302.1 - 0.14 12.4 0.0 0.43 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KFM63302.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 KFM63302.1 - 0.18 12.3 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF1_Zn_bind PF09416.10 KFM63303.1 - 2.1e-77 258.3 3.8 3e-77 257.8 3.8 1.2 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) HTH_Tnp_Tc3_2 PF01498.18 KFM63304.1 - 1.6e-23 82.7 9.3 1.8e-12 47.3 1.8 2.5 2 0 0 2 2 2 2 Transposase HTH_32 PF13565.6 KFM63304.1 - 8.9e-06 26.2 25.0 2.7e-05 24.7 1.2 4.1 2 2 1 3 3 3 2 Homeodomain-like domain DDE_3 PF13358.6 KFM63304.1 - 0.00083 19.1 0.0 14 5.5 0.0 3.4 3 0 0 3 3 3 3 DDE superfamily endonuclease HTH_Crp_2 PF13545.6 KFM63304.1 - 0.0035 17.3 0.7 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KFM63304.1 - 0.029 14.3 0.1 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 KFM63304.1 - 0.036 13.6 1.4 0.74 9.4 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 KFM63304.1 - 0.053 13.6 2.5 0.38 10.9 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix HTH_26 PF13443.6 KFM63304.1 - 0.28 11.6 0.9 41 4.7 0.3 2.5 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Pre-PUA PF17832.1 KFM63305.1 - 2.1e-27 95.6 0.0 3.1e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KFM63305.1 - 6e-20 71.0 0.0 1e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 PUA domain Shugoshin_C PF07557.11 KFM63306.1 - 2.1e-07 30.6 2.6 2.1e-07 30.6 2.6 3.3 3 0 0 3 3 3 2 Shugoshin C terminus HTH_28 PF13518.6 KFM63308.1 - 2.4e-07 30.8 0.2 5.9e-07 29.5 0.0 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM63308.1 - 6.3e-07 29.4 0.5 0.00015 21.8 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM63308.1 - 2.8e-06 26.9 0.4 5e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM63308.1 - 0.00032 20.3 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 KFM63308.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KFM63308.1 - 0.0012 18.7 0.1 0.0019 18.1 0.1 1.6 1 1 1 2 2 2 1 MarR family HTH_38 PF13936.6 KFM63308.1 - 0.0016 18.2 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM63308.1 - 0.0027 17.7 0.5 0.0037 17.3 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM63308.1 - 0.0055 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Tc3 transposase HTH_32 PF13565.6 KFM63308.1 - 0.013 16.1 0.5 0.024 15.3 0.5 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_5 PF01022.20 KFM63308.1 - 0.073 12.9 0.4 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.16 KFM63308.1 - 0.078 12.5 0.1 0.078 12.5 0.1 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 Death PF00531.22 KFM63309.1 - 2.9e-13 49.8 0.2 3.6e-13 49.5 0.2 1.1 1 0 0 1 1 1 1 Death domain SepSecS PF05889.13 KFM63309.1 - 0.021 13.5 0.0 0.022 13.5 0.0 1.0 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS HTH_Tnp_Tc3_2 PF01498.18 KFM63312.1 - 2.5e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63312.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Aldedh PF00171.22 KFM63313.1 - 4.3e-179 595.8 0.0 4.9e-179 595.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sulfotransfer_2 PF03567.14 KFM63315.1 - 1.2e-36 126.9 0.3 1.6e-36 126.6 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFM63316.1 - 7.4e-07 29.3 0.2 9.8e-07 28.9 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFM63317.1 - 5e-05 23.3 0.7 0.00024 21.1 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family UVR PF02151.19 KFM63318.1 - 0.013 15.2 0.7 0.013 15.2 0.7 2.2 2 0 0 2 2 2 0 UvrB/uvrC motif DUF4205 PF13898.6 KFM63320.1 - 7.9e-33 113.8 0.0 8.9e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) HTH_48 PF17906.1 KFM63323.1 - 2.5e-09 37.1 1.3 2.5e-09 37.1 1.3 1.6 2 0 0 2 2 2 1 HTH domain in Mos1 transposase Mga PF05043.13 KFM63323.1 - 0.056 14.0 0.0 0.091 13.4 0.0 1.6 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_10 PF04967.12 KFM63323.1 - 0.068 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 HTH DNA binding domain HTH_6 PF01418.17 KFM63323.1 - 0.086 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_24 PF13412.6 KFM63323.1 - 0.16 11.5 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KFM63323.1 - 0.16 12.1 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain IF2_N PF04760.15 KFM63323.1 - 0.17 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DDE_Tnp_1_7 PF13843.6 KFM63324.1 - 1.9e-21 76.8 0.0 2.1e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 APC_rep PF18797.1 KFM63326.1 - 7.1e-25 87.7 1.9 1e-24 87.2 0.4 2.1 2 0 0 2 2 2 1 Adenomatous polyposis coli (APC) repeat Arm PF00514.23 KFM63326.1 - 2.7e-08 33.6 2.5 2.3e-05 24.2 0.2 3.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat DUF4869 PF16163.5 KFM63326.1 - 0.034 13.9 0.1 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4869) Arm PF00514.23 KFM63327.1 - 2e-16 59.4 4.5 1.6e-08 34.3 0.3 3.9 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat APC_r PF05923.12 KFM63327.1 - 1.9e-08 33.8 0.1 6e-08 32.2 0.1 2.0 1 0 0 1 1 1 1 APC repeat SARS_3b PF12383.8 KFM63327.1 - 0.18 11.9 0.9 0.77 9.9 0.2 2.0 1 1 0 2 2 2 0 Severe acute respiratory syndrome coronavirus 3b protein CH PF00307.31 KFM63329.1 - 5.9e-09 36.1 0.0 2.3e-08 34.2 0.0 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Filamin PF00630.19 KFM63329.1 - 0.00019 22.2 0.0 0.00089 20.0 0.0 2.2 1 0 0 1 1 1 1 Filamin/ABP280 repeat TRAPP PF04051.16 KFM63330.1 - 8.6e-32 109.9 0.0 1e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zf-UBR PF02207.20 KFM63331.1 - 1.8e-12 47.3 13.5 1.8e-12 47.3 13.5 3.9 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 KFM63331.1 - 0.014 15.3 7.0 0.014 15.3 7.0 3.8 3 0 0 3 3 3 0 PHD-finger Kinesin_assoc PF16183.5 KFM63331.1 - 0.062 13.4 2.9 0.13 12.4 2.9 1.5 1 0 0 1 1 1 0 Kinesin-associated SF3A3 PF16837.5 KFM63331.1 - 0.22 12.0 1.1 1.7 9.2 0.1 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Med14 PF08638.11 KFM63332.1 - 3.3e-66 222.4 0.5 6.2e-66 221.5 0.5 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 DUF4371 PF14291.6 KFM63333.1 - 1.7e-30 106.5 0.5 3.2e-30 105.5 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM63333.1 - 1.9e-09 37.2 0.1 6.6e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM63333.1 - 0.042 12.8 7.6 0.055 12.4 0.4 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MAT1 PF06391.13 KFM63333.1 - 2.7 7.8 7.7 2.6 7.8 2.0 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Exonuc_VII_L PF02601.15 KFM63333.1 - 4 6.9 6.9 6.4 6.3 1.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit PDZ PF00595.24 KFM63334.1 - 4.1e-66 219.3 11.7 6.2e-22 77.7 0.7 3.1 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFM63334.1 - 1.5e-27 95.2 7.1 1.3e-10 41.0 0.1 3.3 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFM63334.1 - 3.9e-18 65.5 7.3 8.8e-06 26.0 0.1 3.2 3 0 0 3 3 3 3 PDZ domain CH PF00307.31 KFM63337.1 - 9.7e-21 74.0 0.0 2.4e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM63337.1 - 2.9e-11 43.1 0.1 5.6e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 CAMSAP CH domain FAD_binding_2 PF00890.24 KFM63337.1 - 1.3e-06 27.7 0.1 2.1e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFM63337.1 - 1.6e-06 27.6 0.0 3.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM63337.1 - 1.8e-06 27.4 0.0 9.2e-06 25.1 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFM63337.1 - 6.2e-06 25.7 0.0 9.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM63337.1 - 3.6e-05 22.6 0.0 6.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KFM63337.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KFM63337.1 - 0.00029 20.3 0.2 0.00049 19.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFM63337.1 - 0.00038 21.0 0.1 0.00095 19.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM63337.1 - 0.00068 19.8 0.0 0.0021 18.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM63337.1 - 0.0028 17.3 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase CH_2 PF06294.11 KFM63337.1 - 0.0078 16.3 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 CH-like domain in sperm protein GIDA PF01134.22 KFM63337.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFM63337.1 - 0.027 13.5 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KFM63337.1 - 0.044 14.2 0.0 0.14 12.6 0.0 1.8 2 0 0 2 2 1 0 Putative NAD(P)-binding Thi4 PF01946.17 KFM63337.1 - 0.061 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 KFM63337.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain E2F_CC-MB PF16421.5 KFM63338.1 - 0.035 14.5 0.6 0.035 14.5 0.6 2.8 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain MSV199 PF10553.9 KFM63338.1 - 0.4 10.9 4.5 0.17 12.1 0.2 2.5 2 0 0 2 2 2 0 MSV199 domain DUF3585 PF12130.8 KFM63339.1 - 1.6e-35 122.2 31.0 2.1e-35 121.8 31.0 1.2 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain CRIC_ras_sig PF10534.9 KFM63339.1 - 0.012 15.8 0.5 0.012 15.8 0.5 1.7 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras RNA_pol_Rpb2_7 PF04560.20 KFM63339.1 - 0.042 14.2 0.1 0.092 13.2 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 7 BTB PF00651.31 KFM63340.1 - 1.6e-11 44.4 1.3 1.6e-11 44.4 1.3 2.0 2 1 0 2 2 2 1 BTB/POZ domain CotH PF08757.11 KFM63340.1 - 0.015 14.8 2.3 0.15 11.6 0.0 2.2 1 1 0 2 2 2 0 CotH kinase protein Hom_end_hint PF05203.16 KFM63340.1 - 0.07 13.1 0.1 0.095 12.6 0.1 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint BTB PF00651.31 KFM63341.1 - 8.5e-11 42.1 1.3 9.4e-11 41.9 0.3 1.5 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM63341.1 - 0.019 15.0 0.6 0.18 11.9 0.1 2.5 2 1 0 2 2 2 0 BTB And C-terminal Kelch PAXIP1_C PF15364.6 KFM63341.1 - 0.084 13.2 2.2 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Zn_Tnp_IS1595 PF12760.7 KFM63342.1 - 0.00053 19.9 0.5 0.0012 18.8 0.5 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain RVT_1 PF00078.27 KFM63343.1 - 0.0035 16.9 0.1 0.0041 16.7 0.1 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.25 KFM63344.1 - 8.6e-24 84.1 0.2 1.1e-23 83.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM63344.1 - 2.2e-14 53.6 0.0 2.5e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ras PF00071.22 KFM63346.1 - 7.9e-08 32.1 0.1 8.5e-08 32.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM63346.1 - 3.7e-05 23.9 0.0 3.9e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KFM63346.1 - 0.011 15.4 0.0 0.012 15.4 0.0 1.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM63346.1 - 0.017 15.1 0.0 0.017 15.1 0.0 1.0 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KFM63346.1 - 0.017 15.5 0.0 0.017 15.5 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 KFM63346.1 - 0.043 13.7 0.0 0.043 13.7 0.0 1.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 KFM63346.1 - 0.069 13.2 0.1 0.071 13.2 0.1 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.13 KFM63346.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KFM63346.1 - 0.15 11.7 0.0 0.17 11.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 KFM63346.1 - 0.15 11.2 0.0 0.15 11.2 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 KFM63346.1 - 0.15 12.3 0.0 0.15 12.3 0.0 1.0 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KFM63346.1 - 0.19 11.4 0.1 0.2 11.4 0.1 1.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase BRCT PF00533.26 KFM63347.1 - 3.1e-24 85.1 1.4 1.1e-10 41.7 0.1 3.1 2 1 1 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFM63347.1 - 5.1e-24 84.0 0.7 2.2e-12 46.7 0.1 2.6 2 0 0 2 2 2 2 twin BRCT domain BRCT_2 PF16589.5 KFM63347.1 - 6.8e-17 61.7 0.2 7.3e-07 29.5 0.0 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFM63347.1 - 1.3e-10 41.0 0.2 0.0002 21.2 0.1 2.6 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KFM63347.1 - 0.003 17.8 3.7 1.1 9.6 0.0 3.4 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain DUF4976 PF16347.5 KFM63347.1 - 0.067 13.5 0.9 0.29 11.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4976) Prok-RING_4 PF14447.6 KFM63347.1 - 0.085 12.7 0.2 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF4413 PF14372.6 KFM63347.1 - 0.23 11.8 1.9 24 5.4 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) Treacle PF03546.14 KFM63347.1 - 9.7 4.9 10.9 0.67 8.7 1.1 2.2 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle MADF_DNA_bdg PF10545.9 KFM63349.1 - 1.1e-19 70.5 3.0 2.2e-19 69.5 3.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 KFM63349.1 - 3.9e-06 26.6 1.1 1.2e-05 25.0 1.1 1.9 1 0 0 1 1 1 1 BESS motif Myb_DNA-bind_5 PF13873.6 KFM63349.1 - 0.00084 19.4 1.5 0.0023 17.9 0.9 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain ABC_tran PF00005.27 KFM63350.1 - 7.1e-08 33.1 0.0 8.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter HTH_Tnp_Tc3_2 PF01498.18 KFM63351.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63351.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63353.1 - 2.2e-16 59.9 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63353.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease LRR_8 PF13855.6 KFM63354.1 - 9.3e-85 278.3 76.4 2.2e-15 56.2 4.9 6.8 1 1 8 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFM63354.1 - 1.2e-28 98.6 34.7 1e-06 28.9 1.9 8.3 5 2 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM63354.1 - 1.6e-22 79.9 0.3 3.7e-10 39.8 0.0 3.2 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM63354.1 - 9.2e-16 56.0 31.1 0.22 12.2 0.0 12.6 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.6 KFM63354.1 - 1.1e-11 44.5 9.5 1.2e-05 24.9 0.9 4.2 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 KFM63354.1 - 3.6e-07 29.7 37.3 4.8 7.5 0.3 12.0 12 0 0 12 12 12 2 Leucine Rich repeat LRRNT PF01462.18 KFM63354.1 - 0.0012 18.4 0.8 0.0012 18.4 0.8 4.0 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain LRR_2 PF07723.13 KFM63354.1 - 0.025 15.2 6.3 18 6.2 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat LapA_dom PF06305.11 KFM63354.1 - 0.03 14.1 0.3 0.065 13.1 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain LRR_12 PF18837.1 KFM63354.1 - 0.03 13.9 2.2 1.6 8.4 0.0 4.4 3 1 0 3 3 3 0 Leucine-rich repeat HTH_Tnp_Tc3_2 PF01498.18 KFM63355.1 - 4.4e-16 58.9 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63355.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63355.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63355.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63355.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Membralin PF09746.9 KFM63357.1 - 5.4e-29 101.4 0.2 6.5e-29 101.1 0.2 1.1 1 0 0 1 1 1 1 Tumour-associated protein MASE4 PF17158.4 KFM63357.1 - 0.0005 19.4 1.5 0.0006 19.2 1.5 1.1 1 0 0 1 1 1 1 Membrane-associated sensor, integral membrane domain CBM_26 PF16824.5 KFM63357.1 - 0.15 12.2 0.1 13 6.0 0.0 2.2 2 0 0 2 2 2 0 C-terminal carbohydrate-binding module Membralin PF09746.9 KFM63358.1 - 6.6e-70 236.1 7.6 6.6e-70 236.1 7.6 1.5 2 0 0 2 2 2 1 Tumour-associated protein SPESP1 PF15754.5 KFM63358.1 - 0.051 12.8 4.1 0.071 12.3 4.1 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF4371 PF14291.6 KFM63359.1 - 7.2e-10 38.9 0.0 2e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) CENP-C_C PF11699.8 KFM63361.1 - 3.1e-13 49.8 0.1 6.9e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KFM63361.1 - 0.00049 19.7 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 KFM63361.1 - 0.0039 17.1 0.1 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.12 KFM63361.1 - 0.0092 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) HTH_48 PF17906.1 KFM63362.1 - 2.8e-08 33.8 0.0 5.7e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DDE_3 PF13358.6 KFM63362.1 - 9.2e-08 32.0 0.0 2.3e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM63362.1 - 0.00016 22.2 0.3 0.00016 22.2 0.3 3.8 3 1 1 4 4 4 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63362.1 - 0.00099 19.3 0.7 0.0037 17.5 0.4 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 KFM63362.1 - 0.002 17.9 0.3 0.17 11.7 0.0 3.0 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KFM63362.1 - 0.0024 17.4 0.6 0.0093 15.5 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_10 PF04967.12 KFM63362.1 - 0.0042 16.8 0.0 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 HTH DNA binding domain HTH_17 PF12728.7 KFM63362.1 - 0.0058 16.8 0.3 0.27 11.5 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.7 KFM63362.1 - 0.037 14.0 0.1 0.084 12.9 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM63362.1 - 0.043 13.2 0.1 0.12 11.8 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 KFM63362.1 - 0.063 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KFM63362.1 - 0.1 12.8 0.5 4.7 7.4 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Mga PF08280.11 KFM63362.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain ANT PF03374.14 KFM63362.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain AA_kinase PF00696.28 KFM63363.1 - 0.12 11.9 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Amino acid kinase family DDE_3 PF13358.6 KFM63364.1 - 5.1e-09 36.0 0.0 7.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease STATa_Ig PF18214.1 KFM63365.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.0 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain Eaf7 PF07904.13 KFM63367.1 - 1.1e-07 32.2 0.3 2.1e-07 31.3 0.3 1.4 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 HTH_Tnp_Tc3_2 PF01498.18 KFM63369.1 - 2.5e-16 59.7 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63369.1 - 2.9e-13 49.8 0.0 5.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HN PF00423.19 KFM63370.1 - 0.0032 16.3 0.5 0.0038 16.1 0.5 1.0 1 0 0 1 1 1 1 Haemagglutinin-neuraminidase HalX PF08663.10 KFM63370.1 - 0.005 17.1 1.9 0.008 16.5 1.9 1.3 1 0 0 1 1 1 1 HalX domain ApoO PF09769.9 KFM63370.1 - 0.019 14.9 0.4 0.037 14.0 0.4 1.4 1 0 0 1 1 1 0 Apolipoprotein O FlaC_arch PF05377.11 KFM63370.1 - 0.02 15.3 4.2 0.038 14.4 4.2 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 KFM63370.1 - 0.021 15.1 0.6 0.044 14.1 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF885 PF05960.11 KFM63370.1 - 0.022 14.4 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) COG2 PF06148.11 KFM63370.1 - 0.031 14.4 5.0 0.032 14.3 4.1 1.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 REF PF05755.12 KFM63370.1 - 0.083 12.7 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DUF1664 PF07889.12 KFM63370.1 - 0.12 12.4 1.5 0.16 12.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 KFM63370.1 - 0.15 11.9 4.7 0.19 11.6 4.7 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tnp_22_trimer PF17489.2 KFM63370.1 - 0.3 11.1 6.1 0.44 10.6 1.8 3.1 1 1 1 2 2 2 0 L1 transposable element trimerization domain DUF5446 PF17522.2 KFM63370.1 - 0.46 10.7 5.6 0.75 10.0 1.6 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5446) DUF16 PF01519.16 KFM63370.1 - 1.6 9.3 5.6 2.2 8.8 4.2 1.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 Metallophos PF00149.28 KFM63371.1 - 5.4e-38 131.6 0.1 8.6e-38 130.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 KFM63371.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) zf-H2C2_2 PF13465.6 KFM63372.1 - 7.1e-68 222.2 90.3 6.7e-08 32.6 0.2 13.2 13 0 0 13 13 13 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63372.1 - 3.8e-56 184.5 113.0 2.4e-06 27.7 1.0 13.6 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63372.1 - 6.9e-42 138.5 108.3 0.00039 21.0 1.3 13.6 14 0 0 14 14 13 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM63372.1 - 4.7e-21 74.3 97.7 0.0048 16.9 0.6 14.0 13 1 0 13 13 13 11 C2H2-type zinc finger zf-met PF12874.7 KFM63372.1 - 1.8e-10 40.8 86.8 0.0088 16.4 1.0 13.1 14 0 0 14 14 13 9 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KFM63372.1 - 4e-10 39.3 50.2 0.28 11.1 0.4 12.5 13 0 0 13 13 12 3 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFM63372.1 - 8.2e-08 32.3 76.1 0.14 12.5 0.0 13.7 13 2 1 14 14 13 6 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM63372.1 - 4.7e-07 30.0 15.3 0.094 13.0 0.4 7.0 4 3 2 6 6 6 2 BolA-like protein GAGA PF09237.11 KFM63372.1 - 7.8e-05 22.4 15.9 0.54 10.1 0.0 6.4 4 4 3 7 7 7 2 GAGA factor ADK_lid PF05191.14 KFM63372.1 - 0.00016 21.6 42.4 1.6 8.7 1.5 9.1 5 2 5 10 10 10 5 Adenylate kinase, active site lid FYVE PF01363.21 KFM63372.1 - 0.00031 20.8 72.8 0.01 16.0 8.8 8.4 2 2 1 5 5 5 2 FYVE zinc finger GATase_2 PF00310.21 KFM63372.1 - 0.0016 17.2 9.6 0.47 9.1 0.1 3.1 1 1 1 3 3 3 3 Glutamine amidotransferases class-II zf-H2C2_5 PF13909.6 KFM63372.1 - 0.0018 18.0 84.3 0.0019 17.9 0.6 12.4 12 0 0 12 12 12 4 C2H2-type zinc-finger domain Mycoplasma_p37 PF06646.11 KFM63372.1 - 0.073 12.3 0.0 8.2 5.6 0.0 2.3 2 0 0 2 2 2 0 High affinity transport system protein p37 zf_UBZ PF18439.1 KFM63372.1 - 0.1 12.2 56.4 1.8 8.2 0.2 12.2 13 0 0 13 13 13 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFM63372.1 - 0.17 11.7 0.2 0.17 11.7 0.2 10.1 11 0 0 11 11 11 0 zinc-finger C2H2-type Baculo_IE-1 PF05290.11 KFM63372.1 - 1.6 8.6 44.1 3.3 7.6 0.2 8.1 1 1 7 8 8 8 0 Baculovirus immediate-early protein (IE-0) zinc_ribbon_15 PF17032.5 KFM63372.1 - 6.8 7.5 59.9 0.79 10.5 0.3 7.1 3 2 5 8 8 8 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM63372.1 - 7 6.9 49.1 1.7 8.8 1.2 8.8 4 2 5 9 9 9 0 Zinc ribbon domain HTH_Tnp_Tc5 PF03221.16 KFM63374.1 - 0.024 14.6 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Peptidase_S9 PF00326.21 KFM63376.1 - 2.2e-16 60.0 0.0 8.2e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFM63376.1 - 7e-05 22.6 0.2 0.13 11.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM63376.1 - 0.0029 16.9 0.1 1.9 7.7 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFM63376.1 - 0.1 12.4 0.0 0.94 9.3 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold PCI PF01399.27 KFM63377.1 - 5.4e-11 42.9 0.8 1.8e-10 41.3 0.8 1.9 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 KFM63377.1 - 6.9e-10 38.4 4.9 4.8e-09 35.8 2.8 2.9 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix zf-H2C2_2 PF13465.6 KFM63378.1 - 6e-74 241.4 65.8 8.8e-08 32.3 0.4 12.2 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63378.1 - 2.3e-54 178.9 89.2 1.3e-05 25.3 2.0 11.5 12 0 0 12 12 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63378.1 - 7.8e-38 125.9 79.4 0.00024 21.7 1.3 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM63378.1 - 2.7e-35 119.7 83.1 0.00047 20.4 1.5 11.2 11 0 0 11 11 11 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63378.1 - 6.9e-23 80.4 49.6 0.0099 16.1 0.4 10.5 10 0 0 10 10 10 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM63378.1 - 6.8e-16 57.8 60.6 0.0037 17.2 0.6 11.9 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63378.1 - 1.3e-09 37.7 64.8 0.044 13.5 0.5 12.1 12 0 0 12 12 12 7 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM63378.1 - 7.6e-08 32.3 37.8 0.71 10.0 0.4 10.5 8 2 3 11 11 11 5 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM63378.1 - 1.5e-05 24.5 50.2 0.11 12.1 0.3 10.5 6 3 5 11 11 11 3 MYST family zinc finger domain zf-RRPl_C4 PF17026.5 KFM63378.1 - 2e-05 24.6 40.3 0.062 13.4 3.7 4.4 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type ADK_lid PF05191.14 KFM63378.1 - 2.3e-05 24.3 26.4 0.077 13.0 0.6 6.9 2 1 4 6 6 6 2 Adenylate kinase, active site lid BolA PF01722.18 KFM63378.1 - 0.0019 18.4 11.0 11 6.3 0.6 6.4 1 1 2 5 5 5 0 BolA-like protein Zf_RING PF16744.5 KFM63378.1 - 0.0059 16.7 53.3 0.07 13.2 1.1 10.3 1 1 9 10 10 10 1 KIAA1045 RING finger zf-DBF PF07535.12 KFM63378.1 - 0.0067 16.5 31.0 12 6.1 0.1 9.0 10 0 0 10 10 10 0 DBF zinc finger TRAF6_Z2 PF18048.1 KFM63378.1 - 0.011 15.8 63.2 0.018 15.1 0.8 10.7 11 0 0 11 11 11 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_9 PF16293.5 KFM63378.1 - 0.018 14.9 50.9 0.27 11.1 0.6 10.6 5 2 6 11 11 11 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM63378.1 - 0.024 14.8 48.1 4.6 7.5 11.5 5.8 2 2 2 4 4 3 0 FYVE zinc finger DUF4764 PF15961.5 KFM63378.1 - 0.3 9.7 33.4 1.5 7.4 0.5 6.5 2 2 3 7 7 7 0 Domain of unknown function (DUF4764) Zn_ribbon_SprT PF17283.2 KFM63378.1 - 2.2 8.3 30.9 0.32 10.9 0.5 7.5 8 1 0 8 8 8 0 SprT-like zinc ribbon domain zf-FPG_IleRS PF06827.14 KFM63378.1 - 2.5 8.1 29.7 9.9 6.1 0.1 9.3 11 0 0 11 11 11 0 Zinc finger found in FPG and IleRS zinc_ribbon_15 PF17032.5 KFM63378.1 - 3.2 8.6 40.6 6.3 7.6 1.7 5.7 1 1 5 6 6 6 0 zinc-ribbon family DUF2256 PF10013.9 KFM63378.1 - 6.8 6.9 42.3 7.9 6.7 0.0 10.3 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.6 KFM63380.1 - 2.9e-73 239.2 60.6 2.7e-09 37.0 0.3 10.1 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63380.1 - 5.3e-46 152.6 85.2 8.3e-06 26.0 3.3 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63380.1 - 1.1e-32 109.8 77.2 0.00089 19.9 2.5 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM63380.1 - 5.7e-25 86.9 71.5 0.0019 18.5 1.1 9.2 9 0 0 9 9 9 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM63380.1 - 4.4e-18 64.8 62.2 6.9e-05 22.7 0.1 9.8 9 1 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM63380.1 - 7.3e-16 58.0 63.9 0.0014 18.8 0.5 9.5 8 1 1 9 9 9 7 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM63380.1 - 4.3e-09 36.0 26.9 0.083 12.7 0.1 8.0 1 1 8 9 9 9 5 GAGA factor zf-C2H2_2 PF12756.7 KFM63380.1 - 1.7e-05 25.0 65.9 0.78 10.1 1.4 9.0 1 1 8 9 9 9 5 C2H2 type zinc-finger (2 copies) Tox-HNH-HHH PF15637.6 KFM63380.1 - 5.3e-05 23.3 6.5 0.49 10.6 0.0 4.7 1 1 4 5 5 5 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Sec23_Sec24 PF04810.15 KFM63380.1 - 6e-05 23.0 35.6 0.68 10.0 0.1 8.9 7 2 2 9 9 9 2 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM63380.1 - 0.00011 21.7 47.3 0.21 11.2 0.7 8.9 3 2 6 9 9 9 3 MYST family zinc finger domain ADK_lid PF05191.14 KFM63380.1 - 0.00014 21.8 31.3 0.26 11.3 2.1 6.3 3 2 3 6 6 6 4 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KFM63380.1 - 0.001 18.8 56.5 0.095 12.5 1.5 9.6 10 0 0 10 10 9 4 C2H2-type zinc-finger domain zf-DBF PF07535.12 KFM63380.1 - 0.0011 19.1 42.5 3.6 7.8 0.2 8.7 9 0 0 9 9 9 1 DBF zinc finger zf-C2H2_9 PF16293.5 KFM63380.1 - 0.0012 18.6 38.7 2.5 8.0 0.1 8.8 3 2 6 9 9 9 1 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM63380.1 - 0.0015 18.8 17.6 0.39 11.0 1.0 5.3 1 1 4 5 5 5 2 BolA-like protein C1_1 PF00130.22 KFM63380.1 - 0.0059 16.5 47.8 3.1 7.8 2.4 7.9 1 1 7 8 8 8 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 KFM63380.1 - 0.0079 16.3 35.4 0.22 11.6 5.9 4.2 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type Yop-YscD_ppl PF16693.5 KFM63380.1 - 0.018 14.5 0.0 3.6 7.0 0.0 2.4 1 1 1 2 2 2 0 Inner membrane component of T3SS, periplasmic domain YyzF PF14116.6 KFM63380.1 - 0.079 13.0 26.4 11 6.1 0.3 8.5 9 0 0 9 9 9 0 YyzF-like protein Prok-RING_1 PF14446.6 KFM63380.1 - 0.08 12.9 36.4 5.9 6.9 0.1 8.8 9 0 0 9 9 9 0 Prokaryotic RING finger family 1 AMP_N PF05195.16 KFM63380.1 - 0.13 12.0 0.1 41 3.9 0.0 3.9 3 1 0 4 4 4 0 Aminopeptidase P, N-terminal domain zf-C2H2_8 PF15909.5 KFM63380.1 - 0.14 12.5 40.5 0.039 14.2 3.4 4.9 1 1 4 5 5 5 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFM63380.1 - 0.14 12.9 37.0 3.5 8.5 0.7 4.8 2 2 2 4 4 4 0 zinc-ribbon family PqqA PF08042.11 KFM63380.1 - 0.27 11.3 0.6 2e+02 2.2 0.0 4.5 5 0 0 5 5 5 0 PqqA family HNH_5 PF14279.6 KFM63380.1 - 0.36 10.7 47.0 1.5 8.8 0.1 8.4 3 2 4 7 7 7 0 HNH endonuclease Zn-ribbon_8 PF09723.10 KFM63380.1 - 0.42 10.8 37.7 4.8 7.4 0.2 6.8 2 1 5 7 7 7 0 Zinc ribbon domain Z1 PF10593.9 KFM63380.1 - 0.64 9.5 3.8 4.5 6.7 0.0 2.6 2 1 0 2 2 2 0 Z1 domain zf_UBZ PF18439.1 KFM63380.1 - 1.6 8.4 42.7 2.7 7.7 0.2 9.0 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 KFM63380.1 - 5.2 7.3 37.1 39 4.5 0.1 8.9 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFM63380.1 - 8.6 6.4 43.5 16 5.5 0.3 8.9 9 0 0 9 9 9 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFM63381.1 - 9.5e-97 313.5 88.3 3.5e-07 30.3 1.8 15.1 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63381.1 - 1.2e-69 227.1 118.0 1.4e-05 25.3 0.4 15.1 15 0 0 15 15 15 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63381.1 - 4.6e-48 157.7 108.3 0.00039 21.0 0.5 15.1 15 0 0 15 15 15 14 C2H2-type zinc finger zf-met PF12874.7 KFM63381.1 - 1.2e-38 130.4 110.5 0.00077 19.8 3.3 14.9 14 1 1 15 15 15 14 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63381.1 - 5.6e-27 93.4 78.8 0.0015 18.8 0.4 14.2 14 0 0 14 14 14 12 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM63381.1 - 2.9e-20 71.8 81.0 0.071 13.1 0.3 14.3 14 0 0 14 14 14 12 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63381.1 - 4.7e-19 67.8 65.3 0.024 14.4 0.3 15.3 15 0 0 15 15 15 9 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM63381.1 - 2.1e-11 43.7 51.5 0.17 12.0 0.3 13.4 11 3 3 14 14 14 4 Sec23/Sec24 zinc finger BolA PF01722.18 KFM63381.1 - 1.3e-05 25.3 27.8 2.3 8.6 0.2 9.6 2 2 8 10 10 10 3 BolA-like protein Mga PF05043.13 KFM63381.1 - 0.00015 22.3 11.3 1.7 9.3 0.1 5.9 5 2 1 6 6 6 2 Mga helix-turn-helix domain ADK_lid PF05191.14 KFM63381.1 - 0.00067 19.6 42.0 1.3 9.1 0.9 8.7 2 1 6 9 9 9 4 Adenylate kinase, active site lid VirE1 PF12189.8 KFM63381.1 - 0.013 15.6 3.5 3.5 7.8 0.1 4.0 3 1 0 3 3 3 0 Single-strand DNA-binding protein TRAF6_Z2 PF18048.1 KFM63381.1 - 0.02 15.0 74.8 0.31 11.1 2.2 11.4 13 0 0 13 13 13 0 TNF receptor-associated factor 6 zinc finger 2 TAFII28 PF04719.14 KFM63381.1 - 0.024 14.7 0.6 16 5.7 0.1 4.4 4 1 0 4 4 4 0 hTAFII28-like protein conserved region DUF2256 PF10013.9 KFM63381.1 - 0.025 14.7 53.6 3.3 7.9 0.1 13.5 14 0 0 14 14 14 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CHCC PF10276.9 KFM63381.1 - 0.035 14.1 17.2 36 4.5 0.0 9.3 11 0 0 11 11 10 0 Zinc-finger domain zf-MYST PF17772.1 KFM63381.1 - 0.097 12.3 0.2 0.097 12.3 0.2 13.3 6 3 8 14 14 14 0 MYST family zinc finger domain zf-RRPl_C4 PF17026.5 KFM63381.1 - 0.2 11.7 57.1 1.1 9.4 6.4 6.1 1 1 7 8 8 8 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM63381.1 - 0.24 11.5 49.6 15 5.8 0.1 11.7 14 0 0 14 14 14 0 DBF zinc finger FYVE PF01363.21 KFM63381.1 - 0.91 9.7 72.0 0.59 10.3 6.7 7.0 1 1 6 7 7 7 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFM63381.1 - 1.1 9.6 96.6 4.4 7.7 1.3 11.8 1 1 10 11 11 9 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM63382.1 - 2.8e-79 258.3 92.9 6.7e-08 32.6 0.1 14.8 15 0 0 15 15 15 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63382.1 - 4.3e-65 212.7 122.2 2e-05 24.8 1.6 14.4 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63382.1 - 4.9e-44 145.2 110.4 0.0026 18.5 1.8 14.5 14 0 0 14 14 14 14 C2H2-type zinc finger zf-met PF12874.7 KFM63382.1 - 7.2e-39 131.1 104.8 0.00043 20.6 0.5 14.2 14 0 0 14 14 14 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63382.1 - 1.3e-25 89.1 74.0 0.013 15.8 0.3 13.9 14 0 0 14 14 13 12 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM63382.1 - 2.3e-20 72.1 89.1 0.0014 18.5 0.7 14.2 14 0 0 14 14 14 11 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63382.1 - 3.7e-07 29.8 69.4 0.2 11.4 0.2 12.8 13 0 0 13 13 13 7 C2H2-type zinc-finger domain zf-RRPl_C4 PF17026.5 KFM63382.1 - 8.2e-06 25.9 58.7 0.08 13.0 6.3 6.9 1 1 5 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type zf-CHCC PF10276.9 KFM63382.1 - 4.3e-05 23.5 17.3 3.5 7.8 0.0 9.9 10 0 0 10 10 10 1 Zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM63382.1 - 0.0041 17.1 48.1 2.7 8.1 0.1 12.5 12 1 1 13 13 13 1 Sec23/Sec24 zinc finger DUF2256 PF10013.9 KFM63382.1 - 0.014 15.5 52.0 30 4.9 0.2 13.7 14 0 0 14 14 14 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 KFM63382.1 - 0.015 15.1 67.3 1.3 8.9 0.9 13.0 6 3 8 14 14 14 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFM63382.1 - 0.019 14.7 1.8 0.019 14.7 1.8 11.9 13 0 0 13 13 12 0 zinc-finger C2H2-type ADK_lid PF05191.14 KFM63382.1 - 0.029 14.4 49.5 0.3 11.1 1.4 8.3 5 2 2 7 7 7 0 Adenylate kinase, active site lid Complex1_49kDa PF00346.19 KFM63382.1 - 0.029 13.5 0.5 1.4 8.0 0.0 3.0 2 1 2 4 4 4 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zinc_ribbon_15 PF17032.5 KFM63382.1 - 0.063 14.0 53.5 0.16 12.8 0.6 7.3 2 1 4 7 7 6 0 zinc-ribbon family BolA PF01722.18 KFM63382.1 - 0.067 13.5 26.9 2.4 8.5 0.7 7.7 2 2 6 8 8 8 0 BolA-like protein zf-MYST PF17772.1 KFM63382.1 - 0.12 12.0 0.3 0.12 12.0 0.3 12.5 9 4 4 13 13 13 0 MYST family zinc finger domain zf-DBF PF07535.12 KFM63382.1 - 0.32 11.1 48.5 2.2 8.4 0.2 11.4 13 0 0 13 13 12 0 DBF zinc finger Aminotran_1_2 PF00155.21 KFM63386.1 - 7.5e-56 189.9 0.0 9.2e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 KFM63387.1 - 8.3e-12 44.9 0.0 9e-12 44.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II VWC PF00093.18 KFM63388.1 - 2.4e-12 46.9 39.9 0.00051 20.3 2.0 3.4 3 0 0 3 3 3 3 von Willebrand factor type C domain TILa PF12714.7 KFM63388.1 - 3.3e-05 23.8 30.9 0.00024 21.0 3.4 3.4 3 0 0 3 3 3 3 TILa domain DUF4948 PF16306.5 KFM63389.1 - 0.05 13.4 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4948) HTH_Tnp_Tc3_2 PF01498.18 KFM63390.1 - 5.3e-16 58.6 4.3 5.5e-16 58.6 2.2 2.2 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM63390.1 - 5.9e-14 52.1 0.0 2.1e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63390.1 - 1.9e-07 30.8 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63390.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63390.1 - 2 9.1 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Exo_endo_phos_2 PF14529.6 KFM63391.1 - 8e-21 74.1 6.1 8e-21 74.1 6.1 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DUF5626 PF18540.1 KFM63391.1 - 0.011 16.3 1.3 0.011 16.3 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5626) Exo_endo_phos PF03372.23 KFM63391.1 - 0.018 14.6 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-H2C2_2 PF13465.6 KFM63392.1 - 1.1e-48 161.5 63.2 3.3e-10 39.9 0.3 9.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63392.1 - 4.8e-37 124.4 74.7 6.9e-07 29.4 2.1 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63392.1 - 2.3e-30 102.6 68.6 0.0005 20.7 0.6 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM63392.1 - 6.4e-12 45.2 55.4 0.0093 15.9 0.7 8.5 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.7 KFM63392.1 - 3.5e-11 43.1 58.8 0.0049 17.2 1.3 8.0 8 0 0 8 8 8 7 Zinc-finger of C2H2 type BolA PF01722.18 KFM63392.1 - 8.2e-09 35.6 10.4 0.061 13.6 0.1 5.7 1 1 3 6 6 6 2 BolA-like protein zf-C2H2_11 PF16622.5 KFM63392.1 - 1.4e-07 31.1 48.3 0.078 12.7 0.1 8.0 8 0 0 8 8 8 5 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM63392.1 - 1.8e-07 30.8 12.2 0.00023 20.8 1.7 8.5 9 0 0 9 9 9 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM63392.1 - 7.8e-06 26.0 46.8 0.078 13.3 0.2 7.9 7 1 1 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM63392.1 - 0.00015 21.7 30.0 0.52 10.4 0.3 6.6 5 1 2 7 7 7 3 Sec23/Sec24 zinc finger Baculo_IE-1 PF05290.11 KFM63392.1 - 0.00034 20.6 20.5 2.9 7.9 1.0 5.5 1 1 4 5 5 5 2 Baculovirus immediate-early protein (IE-0) Ndufs5 PF10200.9 KFM63392.1 - 0.03 14.6 3.8 13 6.1 0.5 3.8 1 1 2 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Zn-ribbon_8 PF09723.10 KFM63392.1 - 0.099 12.8 28.6 0.68 10.1 1.7 5.7 2 2 5 7 7 7 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFM63392.1 - 0.15 12.0 31.5 1.4 8.9 0.3 7.2 7 0 0 7 7 7 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM63392.1 - 0.29 11.3 26.6 11 6.2 0.1 7.4 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_11 PF17123.5 KFM63392.1 - 0.35 10.7 15.3 6.2 6.7 0.5 5.5 5 0 0 5 5 5 0 RING-like zinc finger TRAF6_Z2 PF18048.1 KFM63392.1 - 1.5 9.0 0.0 0.87 9.7 0.0 6.9 8 0 0 8 8 8 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_2 PF12756.7 KFM63392.1 - 3.3 8.1 52.6 4.1 7.8 3.2 7.8 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) U71 PF17474.2 KFM63392.1 - 9.2 6.3 10.3 7.8 6.5 0.2 4.0 5 0 0 5 5 5 0 Tegument protein UL11 homolog DUF4200 PF13863.6 KFM63393.1 - 0.81 10.1 4.2 13 6.2 0.3 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Arrestin_N PF00339.29 KFM63394.1 - 3.3e-18 66.1 0.3 3.7e-18 66.0 0.3 1.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KFM63394.1 - 0.0026 17.0 0.1 0.0027 16.9 0.1 1.0 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 KFM63394.1 - 0.013 16.0 0.0 0.013 16.0 0.0 1.0 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KFM63394.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Arrestin_N terminal like RhoGAP PF00620.27 KFM63395.1 - 1.3e-44 151.7 0.0 3.5e-44 150.3 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain SH3_1 PF00018.28 KFM63395.1 - 5e-14 51.6 0.0 1.1e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM63395.1 - 2.9e-10 39.8 0.0 6.6e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM63395.1 - 5.1e-09 35.7 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Sda PF08970.10 KFM63395.1 - 1.2 8.9 4.3 0.95 9.3 0.3 2.8 3 0 0 3 3 3 0 Sporulation inhibitor A DUF4164 PF13747.6 KFM63395.1 - 2.2 8.6 11.2 7.9 6.8 0.7 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 KFM63395.1 - 2.3 8.6 8.8 0.38 11.2 2.4 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CCDC53 PF10152.9 KFM63396.1 - 0.00025 21.5 0.1 0.00036 21.0 0.1 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex MerR-DNA-bind PF09278.11 KFM63396.1 - 0.01 16.4 2.1 0.01 16.4 0.1 1.8 2 0 0 2 2 2 0 MerR, DNA binding PV-1 PF06637.11 KFM63396.1 - 0.013 14.3 0.2 0.014 14.2 0.2 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Dynactin_p22 PF07426.11 KFM63396.1 - 0.02 14.8 0.9 2.5 7.9 0.0 2.1 1 1 1 2 2 2 0 Dynactin subunit p22 pP_pnuc_1 PF18165.1 KFM63396.1 - 0.034 14.0 0.1 0.044 13.7 0.1 1.0 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease PEARLI-4 PF05278.12 KFM63396.1 - 0.043 13.4 0.2 0.043 13.4 0.2 1.0 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) BMFP PF04380.13 KFM63396.1 - 0.071 13.6 1.5 0.43 11.1 1.5 2.1 1 1 0 1 1 1 0 Membrane fusogenic activity ECSIT PF06239.11 KFM63396.1 - 0.097 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway HTH_Tnp_Tc3_2 PF01498.18 KFM63397.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63397.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63397.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63397.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63397.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63398.1 - 3.6e-16 59.2 3.4 5.4e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63398.1 - 1.1e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63398.1 - 1.7e-06 27.6 1.1 6.3e-06 25.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63398.1 - 0.0046 16.7 0.6 0.013 15.3 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63398.1 - 9.3 6.9 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Guanylate_cyc PF00211.20 KFM63400.1 - 2e-66 223.1 0.0 1.1e-65 220.8 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KFM63400.1 - 3e-40 138.1 0.0 5.2e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM63400.1 - 1.6e-31 109.6 0.0 3.1e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 KFM63400.1 - 2.6e-05 23.7 0.8 4.1e-05 23.1 0.8 1.3 1 0 0 1 1 1 1 Heme NO binding associated RE_ApaLI PF09499.10 KFM63400.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63401.1 - 4.1e-16 59.0 3.5 5.6e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63401.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63401.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63401.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63401.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Sulfotransfer_1 PF00685.27 KFM63402.1 - 8.4e-50 169.7 0.1 3.8e-49 167.6 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM63402.1 - 7.3e-06 26.5 0.0 0.011 16.1 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family ZapB PF06005.12 KFM63404.1 - 0.004 17.6 5.6 0.004 17.6 5.6 10.2 6 2 1 7 7 7 3 Cell division protein ZapB DUF1640 PF07798.11 KFM63405.1 - 0.0071 16.4 4.3 0.0071 16.4 4.3 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1640) Filament PF00038.21 KFM63405.1 - 0.011 15.3 4.9 0.016 14.8 4.9 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF5082 PF16888.5 KFM63405.1 - 0.013 15.8 0.5 0.013 15.8 0.5 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) GIT_CC PF16559.5 KFM63405.1 - 0.028 14.3 0.4 0.028 14.3 0.4 4.4 4 2 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 KFM63405.1 - 0.049 13.7 12.6 0.077 13.0 5.9 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cob_adeno_trans PF01923.18 KFM63405.1 - 0.061 13.5 1.4 0.15 12.2 1.3 1.7 1 1 0 1 1 1 0 Cobalamin adenosyltransferase ZapB PF06005.12 KFM63405.1 - 0.084 13.3 6.9 2.1 8.9 0.7 3.1 2 1 1 3 3 3 0 Cell division protein ZapB Myosin_tail_1 PF01576.19 KFM63405.1 - 0.15 9.9 10.0 0.0047 14.8 3.7 1.5 2 0 0 2 2 2 0 Myosin tail ADIP PF11559.8 KFM63405.1 - 0.15 12.1 9.3 1.1 9.3 0.1 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KFM63405.1 - 0.15 12.2 5.5 7 6.8 0.2 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFM63405.1 - 0.2 10.5 9.6 0.018 13.9 3.1 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 KFM63405.1 - 0.2 11.4 9.5 0.037 13.8 4.5 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 Fib_alpha PF08702.10 KFM63405.1 - 0.36 11.0 10.6 0.099 12.8 3.0 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 KFM63405.1 - 0.4 10.5 8.4 0.073 12.9 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PI_PP_I PF18363.1 KFM63405.1 - 0.41 10.8 3.4 8.5 6.6 0.4 3.0 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain GAS PF13851.6 KFM63405.1 - 0.42 9.9 10.2 0.079 12.3 3.3 2.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KFM63405.1 - 0.58 10.2 7.3 3.8 7.6 0.2 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 KFM63405.1 - 0.67 10.6 13.0 0.74 10.5 0.6 3.2 2 2 1 3 3 3 0 Initiation control protein YabA DUF3450 PF11932.8 KFM63405.1 - 0.83 8.9 4.9 0.096 12.0 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 KFM63405.1 - 1.8 9.0 7.3 0.37 11.2 2.1 2.4 2 1 0 2 2 2 0 Centromere protein H (CENP-H) bZIP_1 PF00170.21 KFM63405.1 - 1.9 8.6 7.0 0.43 10.7 0.2 3.2 2 1 2 4 4 4 0 bZIP transcription factor DUF1664 PF07889.12 KFM63405.1 - 3.4 7.7 8.4 0.78 9.8 2.3 2.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 KFM63405.1 - 3.7 7.8 11.5 0.32 11.2 1.5 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding CC2-LZ PF16516.5 KFM63405.1 - 7 7.1 10.8 16 5.9 0.2 2.9 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator EHD_N PF16880.5 KFM63406.1 - 9.1e-08 31.9 9.2 0.27 11.2 0.1 7.5 7 0 0 7 7 7 1 N-terminal EH-domain containing protein TMF_TATA_bd PF12325.8 KFM63406.1 - 0.0012 19.0 223.8 0.0097 16.1 5.7 14.7 4 4 9 14 14 14 6 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KFM63406.1 - 0.0029 17.7 2.4 0.0029 17.7 2.4 13.9 6 3 11 17 17 17 7 Protein of unknown function (DUF1664) VCPO_N PF17897.1 KFM63406.1 - 0.0078 16.0 13.7 10 5.8 0.2 6.1 5 1 1 6 6 6 2 Vanadium chloroperoxidase N-terminal domain SPATA24 PF15175.6 KFM63406.1 - 0.0093 15.9 6.6 0.0093 15.9 6.6 11.3 2 2 8 11 11 11 5 Spermatogenesis-associated protein 24 RuvB_C PF05491.13 KFM63406.1 - 0.055 13.3 21.4 0.57 10.1 0.3 6.7 6 0 0 6 6 6 0 RuvB C-terminal winged helix domain AMNp_N PF10423.9 KFM63406.1 - 0.38 10.4 15.9 6.5 6.4 0.1 6.1 6 0 0 6 6 6 0 Bacterial AMP nucleoside phosphorylase N-terminus Tropomyosin PF00261.20 KFM63406.1 - 0.74 9.1 245.1 0.051 13.0 18.9 10.8 1 1 9 10 10 10 0 Tropomyosin LMWPc PF01451.21 KFM63406.1 - 5.9 7.3 29.8 0.81 10.1 2.0 5.9 3 2 2 5 5 5 0 Low molecular weight phosphotyrosine protein phosphatase CAMSAP_CH PF11971.8 KFM63408.1 - 0.035 13.9 0.1 0.04 13.8 0.1 1.1 1 0 0 1 1 1 0 CAMSAP CH domain Hat1_N PF10394.9 KFM63409.1 - 3.2e-42 144.5 0.6 3.2e-42 144.5 0.6 2.0 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KFM63409.1 - 8.5e-06 26.0 0.0 4.5e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM63409.1 - 0.00037 20.9 0.0 0.00091 19.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM63409.1 - 0.0004 20.3 0.0 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KFM63409.1 - 0.00079 19.1 0.1 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_3 PF13302.7 KFM63409.1 - 0.021 15.5 0.0 0.041 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF761 PF05553.11 KFM63411.1 - 0.11 12.1 0.9 0.22 11.1 0.9 1.5 1 0 0 1 1 1 0 Cotton fibre expressed protein PHD PF00628.29 KFM63412.1 - 1.3e-43 146.7 100.7 8.8e-10 38.3 12.2 7.4 4 3 3 7 7 7 6 PHD-finger PHD_2 PF13831.6 KFM63412.1 - 0.00095 18.7 1.3 0.00095 18.7 1.3 8.6 9 0 0 9 9 9 5 PHD-finger zf-RING_9 PF13901.6 KFM63412.1 - 0.0075 16.3 11.7 0.0075 16.3 11.7 6.4 3 2 2 6 6 6 2 Putative zinc-RING and/or ribbon COG2 PF06148.11 KFM63415.1 - 2.2 8.4 11.8 0.15 12.2 5.1 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FYRC PF05965.14 KFM63416.1 - 1.9e-24 85.6 0.0 8.6e-24 83.5 0.0 2.1 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.14 KFM63416.1 - 1.8e-20 72.5 0.3 7.9e-20 70.5 0.3 2.2 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 KFM63416.1 - 8.6e-15 55.5 0.5 8.6e-15 55.5 0.5 2.8 2 2 0 2 2 2 1 SET domain zf-HC5HC2H_2 PF13832.6 KFM63416.1 - 3.8e-11 43.1 8.6 3.8e-11 43.1 8.6 2.0 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFM63416.1 - 9.1e-10 38.7 10.5 9.1e-10 38.7 10.5 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain cNMP_binding PF00027.29 KFM63417.1 - 4.9e-20 71.4 0.0 1.1e-19 70.3 0.0 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain DDE_3 PF13358.6 KFM63419.1 - 7.3e-12 45.3 0.0 9.3e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM63420.1 - 4.8e-15 55.6 0.0 5.8e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Suf PF05843.14 KFM63421.1 - 6.9 6.6 11.5 9.9 6.0 11.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MFS_1 PF07690.16 KFM63422.1 - 2.4e-62 210.9 24.5 4.8e-62 209.9 23.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM63422.1 - 1.6e-08 33.9 24.0 2.4e-07 30.0 23.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KFM63422.1 - 0.0029 16.1 1.0 0.0029 16.1 1.0 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector PalH PF08733.10 KFM63422.1 - 0.042 12.8 0.2 0.15 11.0 0.0 2.0 1 1 1 2 2 2 0 PalH/RIM21 zf-H2C2_2 PF13465.6 KFM63423.1 - 4.8e-27 93.1 65.4 1.9e-05 24.9 5.8 8.5 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63423.1 - 7.7e-26 89.1 74.2 0.0002 21.6 5.9 8.2 8 0 0 8 8 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63423.1 - 5.1e-18 64.2 64.9 0.00064 20.3 0.6 8.2 8 0 0 8 8 7 7 C2H2-type zinc finger zf-met PF12874.7 KFM63423.1 - 2.2e-11 43.8 56.5 0.014 15.7 2.0 8.2 8 0 0 8 8 7 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63423.1 - 7.2e-09 35.7 46.8 0.043 14.1 0.8 7.5 6 1 1 7 7 7 5 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 KFM63423.1 - 0.00096 19.6 0.6 0.00096 19.6 0.6 5.4 5 0 0 5 5 5 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_3rep PF18868.1 KFM63423.1 - 0.01 16.5 33.7 0.04 14.6 3.3 4.5 3 2 0 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 KFM63423.1 - 0.04 13.8 15.7 0.73 9.8 0.1 4.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFM63423.1 - 0.066 13.2 53.6 0.39 10.8 3.4 7.6 7 0 0 7 7 7 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63423.1 - 0.5 10.2 0.1 0.5 10.2 0.1 8.8 8 2 0 8 8 7 0 C2H2-type zinc-finger domain BolA PF01722.18 KFM63423.1 - 0.78 10.1 10.1 0.53 10.6 1.7 3.1 2 0 0 2 2 2 0 BolA-like protein ADK_lid PF05191.14 KFM63423.1 - 1.5 8.8 16.5 3.1 7.9 1.5 4.6 2 2 2 4 4 4 0 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KFM63423.1 - 2.8 8.1 33.4 0.17 12.0 0.4 6.8 6 1 1 7 7 7 0 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 KFM63423.1 - 3.5 7.5 46.6 0.077 12.8 2.1 7.1 7 0 0 7 7 7 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFM63423.1 - 8.2 6.6 28.2 2.1 8.6 0.4 5.4 3 1 2 5 5 5 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM63423.1 - 9.5 7.0 31.6 12 6.7 4.1 4.4 1 1 4 5 5 5 0 zinc-ribbon family MFS_1 PF07690.16 KFM63424.1 - 4.8e-54 183.6 31.8 1.5e-53 182.0 26.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Hep_59 PF07052.11 KFM63425.1 - 6.2e-32 110.5 4.7 6.2e-32 110.5 4.7 2.5 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Galactosyl_T PF01762.21 KFM63426.1 - 1.5e-35 122.8 0.0 2e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Ank_4 PF13637.6 KFM63428.1 - 2.8e-18 66.0 0.7 1.2e-13 51.2 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM63428.1 - 9.6e-16 58.2 0.0 1.2e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM63428.1 - 2.5e-14 53.2 1.4 1.5e-10 41.1 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM63428.1 - 2.5e-12 45.8 0.0 3.8e-06 26.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFM63428.1 - 4.1e-10 39.6 0.1 0.00036 20.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Oxygenase-NA PF09859.9 KFM63428.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA 7tm_1 PF00001.21 KFM63429.1 - 1.2e-25 90.3 5.0 1.4e-25 90.1 5.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFM63429.1 - 0.00039 19.9 1.8 0.00046 19.6 1.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFM63429.1 - 0.0013 18.5 0.2 0.0018 18.0 0.2 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFM63429.1 - 0.0032 17.1 8.9 0.0051 16.5 8.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KFM63429.1 - 0.056 12.7 3.7 0.068 12.4 3.7 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw WTF PF03303.13 KFM63429.1 - 1.9 8.2 5.5 2.2 8.0 0.2 2.0 2 0 0 2 2 2 0 WTF protein 7tm_1 PF00001.21 KFM63430.1 - 0.0031 16.9 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FAM199X PF15814.5 KFM63431.1 - 2.3e-20 72.9 16.4 1.5e-18 66.9 1.4 2.3 1 1 1 2 2 2 2 Protein family FAM199X Choline_kinase PF01633.20 KFM63431.1 - 0.14 11.7 2.2 9.1 5.8 0.1 2.3 2 1 0 2 2 2 0 Choline/ethanolamine kinase Serpin PF00079.20 KFM63432.1 - 5.5e-53 180.6 0.0 1e-31 110.6 0.0 2.1 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) ADP_ribosyl_GH PF03747.14 KFM63435.1 - 3.9e-60 204.1 0.0 4.6e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase NIR_SIR PF01077.22 KFM63435.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain HTH_11 PF08279.12 KFM63435.1 - 0.2 11.6 2.0 0.25 11.3 0.1 2.2 3 0 0 3 3 3 0 HTH domain TUDOR PF00567.24 KFM63436.1 - 6.9e-20 71.3 0.6 1e-18 67.5 0.0 2.5 2 1 1 3 3 3 1 Tudor domain SPESP1 PF15754.5 KFM63436.1 - 0.03 13.5 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF4852 PF16144.5 KFM63436.1 - 0.033 14.3 0.2 0.058 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) MAGE PF01454.19 KFM63436.1 - 0.041 13.6 0.1 0.058 13.1 0.1 1.2 1 0 0 1 1 1 0 MAGE family TUDOR PF00567.24 KFM63437.1 - 6.2e-06 26.2 0.2 1.6e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Tudor domain Helicase_C PF00271.31 KFM63437.1 - 5.6e-05 23.4 0.0 0.00014 22.2 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain QSOX_Trx1 PF18108.1 KFM63437.1 - 0.091 13.0 0.0 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 QSOX Trx-like domain DUF4371 PF14291.6 KFM63438.1 - 9.8e-07 28.6 1.0 3.3e-06 26.9 1.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4371) HTH_48 PF17906.1 KFM63438.1 - 1.3e-06 28.4 0.0 7.2e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 HTH domain in Mos1 transposase zf-piccolo PF05715.13 KFM63438.1 - 0.084 13.0 2.1 8.7 6.6 0.3 2.8 2 0 0 2 2 2 0 Piccolo Zn-finger TUDOR PF00567.24 KFM63439.1 - 4.1e-12 46.2 0.0 1.3e-11 44.6 0.0 2.0 1 0 0 1 1 1 1 Tudor domain PH_18 PF18469.1 KFM63439.1 - 0.018 15.0 0.3 0.065 13.2 0.3 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain DUF1128 PF06569.11 KFM63439.1 - 0.059 13.4 0.9 0.21 11.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) DDE_3 PF13358.6 KFM63440.1 - 2.8e-16 59.6 0.1 3e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63440.1 - 1.4e-10 41.2 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase DUF4371 PF14291.6 KFM63441.1 - 1.3e-06 28.3 1.0 3.2e-06 26.9 1.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM63441.1 - 0.01 15.4 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger C2H2-type YbfN PF13982.6 KFM63441.1 - 0.24 11.7 2.0 23 5.3 0.2 2.8 2 0 0 2 2 2 0 YbfN-like lipoprotein CompInhib_SCIN PF11546.8 KFM63441.1 - 1.3 9.1 5.1 20 5.3 0.2 3.1 3 0 0 3 3 3 0 Staphylococcal complement inhibitor SCIN UPF0113 PF03657.13 KFM63442.1 - 3.9e-14 52.7 0.0 5.7e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 KFM63442.1 - 8.9e-10 39.0 0.2 1.7e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 KFM63442.1 - 0.034 14.1 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 PUA domain PagP PF07017.11 KFM63442.1 - 0.035 13.5 0.0 0.14 11.6 0.0 1.8 1 1 1 2 2 2 0 Antimicrobial peptide resistance and lipid A acylation protein PagP HTH_28 PF13518.6 KFM63443.1 - 0.00014 21.9 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 KFM63443.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_ISL3 PF13542.6 KFM63443.1 - 0.0075 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KFM63443.1 - 0.022 14.5 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 KFM63443.1 - 0.092 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix GntR PF00392.21 KFM63443.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 KFM63443.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_IclR PF09339.10 KFM63443.1 - 0.19 11.6 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain CAT PF00302.18 KFM63444.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase Neur_chan_LBD PF02931.23 KFM63445.1 - 1.2e-30 106.6 0.5 2e-30 105.9 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM63445.1 - 4.6e-21 76.0 14.2 2.6e-20 73.5 9.3 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HTH_Tnp_Tc3_2 PF01498.18 KFM63446.1 - 5.2e-17 61.9 0.4 9.8e-17 61.0 0.4 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63446.1 - 2.8e-06 27.8 1.4 5.5e-06 26.9 1.4 1.5 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 KFM63446.1 - 2.9e-05 23.9 0.8 0.0048 16.8 0.0 2.5 2 1 0 2 2 2 1 MarR family HTH_24 PF13412.6 KFM63446.1 - 0.00064 19.2 1.0 0.067 12.8 0.0 3.1 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KFM63446.1 - 0.00067 19.6 0.7 0.0059 16.5 0.0 2.3 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_3 PF01381.22 KFM63446.1 - 0.0016 18.5 0.2 0.065 13.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix PAX PF00292.18 KFM63446.1 - 0.0037 17.2 0.0 0.0067 16.3 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_26 PF13443.6 KFM63446.1 - 0.0045 17.4 0.4 4.7 7.7 0.1 2.3 2 0 0 2 2 2 2 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 KFM63446.1 - 0.01 15.6 1.7 0.37 10.6 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain TrmB PF01978.19 KFM63446.1 - 0.025 14.5 0.0 0.67 9.9 0.0 2.3 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 KFM63446.1 - 0.026 14.7 3.9 0.49 10.6 0.2 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM63446.1 - 0.056 13.5 0.9 3.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix Sigma70_r4 PF04545.16 KFM63446.1 - 0.11 12.1 1.6 0.15 11.6 0.1 2.0 3 0 0 3 3 3 0 Sigma-70, region 4 Drf_FH1 PF06346.12 KFM63448.1 - 7.2e-08 32.3 34.5 1e-07 31.8 34.3 1.3 1 1 0 1 1 1 1 Formin Homology Region 1 Drf_FH1 PF06346.12 KFM63450.1 - 0.0013 18.5 14.9 0.0015 18.2 14.9 1.1 1 0 0 1 1 1 1 Formin Homology Region 1 PDZ_6 PF17820.1 KFM63451.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM63451.1 - 0.16 12.3 0.1 0.24 11.8 0.1 1.3 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 KFM63452.1 - 8.4e-84 276.0 10.0 7.5e-15 55.1 0.0 7.0 6 1 1 7 7 7 6 PDZ domain PDZ_6 PF17820.1 KFM63452.1 - 1.1e-61 204.5 3.8 6.1e-13 48.4 0.0 6.3 6 0 0 6 6 6 6 PDZ domain PDZ_2 PF13180.6 KFM63452.1 - 4.3e-33 113.5 0.4 0.00019 21.7 0.0 6.3 6 0 0 6 6 6 6 PDZ domain Tricorn_PDZ PF14685.6 KFM63452.1 - 4.8e-14 52.1 0.9 0.32 11.0 0.0 6.2 6 0 0 6 6 6 5 Tricorn protease PDZ domain GRASP55_65 PF04495.14 KFM63452.1 - 1.4e-05 25.4 0.1 4.3 7.7 0.0 4.6 2 2 3 5 5 5 2 GRASP55/65 PDZ-like domain MoaE PF02391.17 KFM63452.1 - 0.08 13.2 0.2 36 4.7 0.0 4.2 5 0 0 5 5 5 0 MoaE protein F-actin_cap_A PF01267.17 KFM63453.1 - 8e-90 300.9 0.1 9e-90 300.7 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF4131 PF13567.6 KFM63454.1 - 3.3 7.3 5.1 15 5.2 5.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) PID PF00640.23 KFM63455.1 - 1.6e-34 118.9 0.0 4.4e-25 88.3 0.0 2.7 2 1 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.26 KFM63455.1 - 3.4e-05 23.8 1.6 7.2e-05 22.8 1.6 1.6 1 0 0 1 1 1 1 WW domain PTB PF08416.13 KFM63455.1 - 0.00018 21.7 0.1 0.035 14.3 0.0 2.7 3 0 0 3 3 3 2 Phosphotyrosine-binding domain Neur_chan_memb PF02932.16 KFM63456.1 - 3.1e-11 43.8 0.1 3.7e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region UCR_TM PF02921.14 KFM63457.1 - 1.5e-28 99.0 3.5 3.7e-28 97.8 2.6 2.0 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KFM63457.1 - 1.3e-12 47.5 0.0 2.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ubiq-Cytc-red_N PF09165.10 KFM63457.1 - 0.00063 20.6 0.2 0.0014 19.5 0.2 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal FXa_inhibition PF14670.6 KFM63457.1 - 0.31 11.4 3.1 0.59 10.5 3.1 1.3 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site LRR_4 PF12799.7 KFM63458.1 - 1.1e-06 28.8 15.1 0.0041 17.5 6.0 2.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM63458.1 - 0.0019 17.9 11.8 0.081 12.7 0.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 KFM63458.1 - 0.019 14.5 4.1 0.029 13.9 4.1 1.4 1 1 0 1 1 1 0 Leucine-rich repeat PPTA PF01239.22 KFM63459.1 - 1.7e-49 164.2 10.6 9.6e-11 41.1 0.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RabGGT_insert PF07711.11 KFM63459.1 - 7.3e-07 29.6 0.1 1.9e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Rab geranylgeranyl transferase alpha-subunit, insert domain TPR_17 PF13431.6 KFM63459.1 - 0.022 15.1 0.3 31 5.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HSBP1 PF06825.12 KFM63460.1 - 1.9e-28 98.0 4.9 1.9e-28 98.0 4.9 1.4 2 0 0 2 2 2 1 Heat shock factor binding protein 1 CLZ PF16526.5 KFM63460.1 - 0.0023 18.3 0.1 0.0041 17.5 0.1 1.6 1 1 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Exo70 PF03081.15 KFM63460.1 - 0.0051 15.9 0.1 0.0056 15.8 0.1 1.0 1 0 0 1 1 1 1 Exo70 exocyst complex subunit BLOC1_2 PF10046.9 KFM63460.1 - 0.043 14.1 2.3 0.22 11.8 2.3 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EspB PF05802.11 KFM63460.1 - 0.046 13.7 0.6 0.055 13.5 0.6 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein Erythro-docking PF09277.11 KFM63460.1 - 0.051 13.5 0.1 0.54 10.2 0.2 2.0 2 0 0 2 2 2 0 Erythronolide synthase, docking Tetraspanin PF00335.20 KFM63461.1 - 0.027 14.2 0.2 0.36 10.5 0.2 2.0 1 1 0 1 1 1 0 Tetraspanin family Myb_DNA-bind_5 PF13873.6 KFM63462.1 - 2.6e-08 33.8 0.2 2.6e-08 33.8 0.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF2794 PF10984.8 KFM63462.1 - 0.0054 16.8 0.1 0.11 12.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2794) BMF PF15185.6 KFM63462.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis BEN PF10523.9 KFM63463.1 - 6.6e-09 35.9 0.2 2.1e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 BEN domain DUF929 PF06053.11 KFM63463.1 - 0.1 11.9 1.0 0.18 11.1 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) FliD_N PF02465.18 KFM63463.1 - 0.18 12.5 0.7 0.3 11.8 0.1 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus RhoGEF PF00621.20 KFM63464.1 - 1.2e-18 67.9 0.0 1.6e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 RhoGEF domain betaPIX_CC PF16523.5 KFM63465.1 - 7.1e-16 57.8 4.1 1.2e-15 57.0 4.1 1.4 1 0 0 1 1 1 1 betaPIX coiled coil DUF2353 PF09789.9 KFM63465.1 - 0.0025 17.3 6.8 0.0032 16.9 6.8 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Swi5 PF07061.11 KFM63465.1 - 0.079 13.1 0.8 0.18 11.9 0.8 1.6 1 0 0 1 1 1 0 Swi5 Fib_alpha PF08702.10 KFM63465.1 - 0.14 12.4 3.6 0.22 11.7 3.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family WD40_alt PF14077.6 KFM63465.1 - 0.16 11.8 0.8 0.31 11.0 0.8 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF4094 PF13334.6 KFM63465.1 - 1.2 9.6 6.8 2 8.9 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) 7tm_1 PF00001.21 KFM63466.1 - 2.5e-14 53.2 6.3 3.1e-14 52.9 6.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HTH_Tnp_Tc3_2 PF01498.18 KFM63467.1 - 2.4e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63467.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3781 PF12636.7 KFM63468.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) CBM_14 PF01607.24 KFM63469.1 - 2.8e-10 40.2 5.2 4.2e-10 39.6 5.2 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain CwfJ_C_1 PF04677.15 KFM63470.1 - 0.051 13.4 0.1 0.22 11.4 0.0 2.0 2 1 1 3 3 3 0 Protein similar to CwfJ C-terminus 1 T4SS_TraI PF16932.5 KFM63472.1 - 0.0083 15.3 0.0 0.0092 15.2 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system, conjugal DNA-protein transfer ArAE_1_C PF11728.8 KFM63472.1 - 0.091 12.8 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain RasGEF PF00617.19 KFM63473.1 - 1.8e-29 103.2 0.9 1.8e-29 103.2 0.9 2.5 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 KFM63473.1 - 4.5e-11 42.9 0.1 1.4e-10 41.3 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Tam41_Mmp37 PF09139.11 KFM63474.1 - 0.064 12.7 0.1 0.086 12.3 0.1 1.1 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Cadherin PF00028.17 KFM63476.1 - 1.7e-17 63.7 0.0 1.5e-12 47.8 0.0 2.3 2 0 0 2 2 2 2 Cadherin domain Cadherin PF00028.17 KFM63477.1 - 8.2e-45 151.2 4.2 4.1e-21 75.2 0.2 3.7 4 0 0 4 4 4 3 Cadherin domain Cadherin_3 PF16184.5 KFM63477.1 - 0.0011 18.9 5.8 1.6 8.8 0.1 3.5 3 1 0 3 3 3 2 Cadherin-like DUF3085 PF11284.8 KFM63477.1 - 0.016 15.5 0.0 0.079 13.3 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3085) RET_CLD1 PF17756.1 KFM63477.1 - 0.046 14.0 0.0 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 RET Cadherin like domain 1 ZirS_C PF16583.5 KFM63477.1 - 0.21 11.1 9.9 0.039 13.5 2.4 2.7 2 1 0 3 3 3 0 Zinc-regulated secreted antivirulence protein C-terminal domain Cadherin PF00028.17 KFM63479.1 - 9.8e-89 292.0 5.6 1e-23 83.6 0.1 5.1 5 0 0 5 5 5 5 Cadherin domain Cadherin_3 PF16184.5 KFM63479.1 - 2.4e-11 43.6 7.4 0.0018 18.3 0.1 4.3 4 0 0 4 4 4 4 Cadherin-like Cadherin_2 PF08266.12 KFM63479.1 - 2.7e-07 30.3 0.5 0.0069 16.2 0.0 3.8 3 1 0 3 3 3 2 Cadherin-like RET_CLD1 PF17756.1 KFM63479.1 - 5e-07 30.0 0.0 0.19 12.0 0.0 3.3 3 0 0 3 3 3 2 RET Cadherin like domain 1 Cadherin_4 PF17803.1 KFM63479.1 - 1.2e-05 25.9 20.0 0.14 12.8 2.5 4.2 4 0 0 4 4 4 3 Bacterial cadherin-like domain Cadherin_pro PF08758.11 KFM63479.1 - 0.0047 17.0 0.2 1.7 8.8 0.0 3.8 4 0 0 4 4 4 1 Cadherin prodomain like EF-hand_7 PF13499.6 KFM63479.1 - 0.015 15.8 0.1 0.35 11.3 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair Invasin_D3 PF09134.10 KFM63479.1 - 5.5 7.4 9.4 2.4 8.5 0.2 4.0 3 2 0 4 4 4 0 Invasin, domain 3 Cadherin PF00028.17 KFM63480.1 - 1.6e-24 86.2 0.0 1.8e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Cadherin domain Cadherin_2 PF08266.12 KFM63480.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Cadherin-like RET_CLD1 PF17756.1 KFM63480.1 - 0.025 14.9 0.0 0.037 14.3 0.0 1.4 1 1 0 1 1 1 0 RET Cadherin like domain 1 Cadherin_3 PF16184.5 KFM63480.1 - 0.048 13.7 0.1 11 6.0 0.0 2.3 2 1 0 2 2 2 0 Cadherin-like Cadherin PF00028.17 KFM63481.1 - 4.4e-34 116.8 0.4 1e-21 77.2 0.1 2.1 2 0 0 2 2 2 2 Cadherin domain Cadherin_3 PF16184.5 KFM63481.1 - 0.0065 16.5 1.0 0.0093 16.0 0.2 1.7 2 0 0 2 2 2 1 Cadherin-like Cadherin_2 PF08266.12 KFM63481.1 - 0.0098 15.7 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 2 Cadherin-like MBF2 PF15868.5 KFM63481.1 - 0.052 14.1 0.1 0.12 12.9 0.1 1.8 1 1 0 1 1 1 0 Transcription activator MBF2 CSG2 PF16965.5 KFM63481.1 - 0.21 10.5 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Cadherin PF00028.17 KFM63482.1 - 1.3e-10 41.6 0.0 1.4e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 Cadherin domain Cadherin PF00028.17 KFM63483.1 - 9.7e-34 115.7 0.6 4.4e-21 75.1 0.1 2.5 3 0 0 3 3 3 2 Cadherin domain Cadherin_3 PF16184.5 KFM63483.1 - 2.7e-07 30.5 1.0 0.0017 18.3 0.1 2.8 2 1 1 3 3 3 2 Cadherin-like MBF2 PF15868.5 KFM63483.1 - 0.43 11.1 3.7 0.44 11.1 0.2 2.3 2 1 0 2 2 2 0 Transcription activator MBF2 Cadherin PF00028.17 KFM63484.1 - 5.6e-61 203.0 4.7 2e-22 79.4 0.1 4.1 4 0 0 4 4 4 4 Cadherin domain Cadherin_3 PF16184.5 KFM63484.1 - 6.2e-07 29.4 3.1 0.0028 17.6 0.7 3.3 3 0 0 3 3 3 2 Cadherin-like RET_CLD1 PF17756.1 KFM63484.1 - 1.6e-05 25.2 0.0 0.28 11.5 0.0 4.3 2 1 1 4 4 4 1 RET Cadherin like domain 1 Cadherin_2 PF08266.12 KFM63484.1 - 1.8e-05 24.5 0.0 0.11 12.4 0.0 3.0 3 0 0 3 3 3 2 Cadherin-like Cadherin PF00028.17 KFM63485.1 - 5.1e-10 39.7 0.1 1.8e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Cadherin domain Cadherin_C PF01049.17 KFM63485.1 - 1.3e-09 38.5 4.1 2.1e-08 34.6 0.0 2.5 1 1 1 2 2 2 2 Cadherin cytoplasmic region DUF4381 PF14316.6 KFM63485.1 - 0.044 14.0 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PRAI PF00697.22 KFM63485.1 - 0.079 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Frag1 PF10277.9 KFM63487.1 - 0.043 13.4 2.3 0.046 13.3 2.3 1.0 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Cadherin PF00028.17 KFM63488.1 - 2e-39 133.9 7.1 1.9e-11 44.2 0.4 5.4 5 0 0 5 5 5 5 Cadherin domain AMP-binding PF00501.28 KFM63489.1 - 1.4e-60 205.1 0.0 1.7e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM63489.1 - 1.4e-20 74.0 0.0 2.5e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFM63490.1 - 2.3e-08 33.0 0.0 2.7e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme zf-H2C2_2 PF13465.6 KFM63491.1 - 2.2e-59 195.3 64.4 1.1e-07 31.9 1.4 10.9 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63491.1 - 6.1e-46 152.4 77.7 1.4e-06 28.4 1.4 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63491.1 - 8.1e-37 122.7 73.5 0.0002 21.9 0.6 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM63491.1 - 5.6e-23 80.6 63.9 0.0013 19.1 1.0 10.3 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63491.1 - 5.5e-14 52.0 46.2 0.53 10.6 0.3 10.2 10 0 0 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM63491.1 - 1e-11 44.5 34.4 0.73 9.7 0.3 9.9 3 2 7 10 10 10 4 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 KFM63491.1 - 1.1e-10 41.2 65.0 0.042 13.8 0.5 9.9 10 0 0 10 10 10 7 C2H2-type zinc finger zf-DBF PF07535.12 KFM63491.1 - 8.4e-09 35.4 33.5 5.4 7.2 0.1 10.0 10 0 0 10 10 10 1 DBF zinc finger zf-H2C2_5 PF13909.6 KFM63491.1 - 2.3e-08 33.6 43.8 0.054 13.3 0.4 9.7 9 0 0 9 9 9 3 C2H2-type zinc-finger domain GAGA PF09237.11 KFM63491.1 - 5.1e-07 29.4 27.8 1.7 8.5 0.1 8.9 1 1 9 10 10 10 4 GAGA factor ADK_lid PF05191.14 KFM63491.1 - 9.8e-06 25.5 27.6 0.69 9.9 0.2 6.3 3 1 5 8 8 8 4 Adenylate kinase, active site lid BolA PF01722.18 KFM63491.1 - 1.7e-05 25.0 13.6 2.9 8.2 0.5 6.1 1 1 5 6 6 6 2 BolA-like protein zf-C2H2_2 PF12756.7 KFM63491.1 - 2.4e-05 24.6 61.0 1.5 9.2 0.4 9.5 1 1 8 9 9 9 3 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.15 KFM63491.1 - 6.8e-05 22.8 31.7 2.1 8.5 0.1 9.6 8 2 2 10 10 10 2 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM63491.1 - 0.00016 21.8 37.2 0.067 13.3 9.5 4.5 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-MYST PF17772.1 KFM63491.1 - 0.00026 20.5 45.3 0.78 9.4 0.2 9.8 5 3 5 10 10 10 3 MYST family zinc finger domain Prok-RING_1 PF14446.6 KFM63491.1 - 0.00086 19.2 33.4 2.6 8.0 2.4 9.4 9 1 0 9 9 9 1 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 KFM63491.1 - 0.0019 17.7 43.2 1.1 8.9 0.2 9.3 10 0 0 10 10 10 4 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 KFM63491.1 - 0.0041 17.2 34.3 11 6.2 0.1 9.7 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) PPL4 PF18188.1 KFM63491.1 - 0.0059 16.6 2.0 0.86 9.5 0.0 4.2 2 1 2 5 5 5 1 Prim-pol 4 Zn-ribbon_8 PF09723.10 KFM63491.1 - 0.0071 16.4 33.3 1.1 9.4 0.4 6.5 5 2 0 6 6 6 3 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFM63491.1 - 0.028 14.3 34.0 4.6 7.3 0.2 8.9 9 0 0 9 9 9 0 zinc-finger of a C2HC-type AMP_N PF05195.16 KFM63491.1 - 0.03 14.1 0.0 3.2 7.5 0.0 3.3 2 2 0 3 3 3 0 Aminopeptidase P, N-terminal domain zinc_ribbon_15 PF17032.5 KFM63491.1 - 0.046 14.5 37.5 2.6 8.8 1.0 5.6 1 1 4 6 6 6 0 zinc-ribbon family Baculo_IE-1 PF05290.11 KFM63491.1 - 0.11 12.5 36.3 12 5.9 8.8 7.4 1 1 2 4 4 4 0 Baculovirus immediate-early protein (IE-0) PqqA PF08042.11 KFM63491.1 - 1.1 9.4 5.6 2.2e+02 2.1 0.0 5.4 6 0 0 6 6 6 0 PqqA family Cg6151-P PF10233.9 KFM63491.1 - 1.3 9.4 2.4 49 4.3 0.0 4.2 1 1 4 6 6 6 0 Uncharacterized conserved protein CG6151-P zf-CHCC PF10276.9 KFM63491.1 - 1.3 9.1 20.6 49 4.1 0.1 7.7 10 0 0 10 10 8 0 Zinc-finger domain HNH_5 PF14279.6 KFM63491.1 - 3.9 7.4 40.0 4.2 7.3 1.0 8.8 6 3 1 7 7 7 0 HNH endonuclease TRAF6_Z2 PF18048.1 KFM63491.1 - 4.5 7.5 34.0 0.19 11.8 0.8 6.7 8 0 0 8 8 7 0 TNF receptor-associated factor 6 zinc finger 2 zf-FCS PF06467.14 KFM63491.1 - 7 6.7 27.4 31 4.6 0.2 8.2 8 1 1 9 9 9 0 MYM-type Zinc finger with FCS sequence motif DUF1917 PF08939.10 KFM63493.1 - 0.081 12.8 0.6 0.19 11.6 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) MENTAL PF10457.9 KFM63494.1 - 2e-55 187.4 10.6 2.4e-55 187.1 10.6 1.1 1 0 0 1 1 1 1 Cholesterol-capturing domain DUF3671 PF12420.8 KFM63494.1 - 1.5 8.9 9.8 0.17 12.0 5.6 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF2456 PF10445.9 KFM63494.1 - 2.9 8.0 8.7 0.39 10.8 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) HTH_Tnp_Tc3_2 PF01498.18 KFM63495.1 - 2.8e-16 59.5 2.2 5.1e-16 58.7 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63495.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Trypsin PF00089.26 KFM63495.1 - 1.5e-13 51.1 0.2 2.5e-13 50.3 0.2 1.3 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KFM63496.1 - 1.2e-38 133.2 0.1 1.3e-38 133.1 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KFM63497.1 - 6.1e-61 206.0 0.0 7e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM63497.1 - 5.7e-06 27.3 0.2 1.6e-05 25.9 0.2 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM63497.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) DUF316 PF03761.15 KFM63497.1 - 0.028 14.0 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 Trypsin PF00089.26 KFM63498.1 - 1.5e-34 119.7 2.3 1.8e-34 119.5 2.3 1.0 1 0 0 1 1 1 1 Trypsin Exostosin PF03016.15 KFM63498.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Exostosin family Trypsin PF00089.26 KFM63499.1 - 3.6e-64 216.6 0.1 4.6e-64 216.3 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM63499.1 - 4.2e-07 31.0 0.1 7.1e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM63499.1 - 0.0049 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFM63500.1 - 1.8e-62 211.1 0.1 2.2e-62 210.7 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM63500.1 - 1.3e-05 26.1 0.1 2.5e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM63500.1 - 0.066 13.6 0.2 0.17 12.3 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Abhydrolase_1 PF00561.20 KFM63501.1 - 5e-15 55.9 0.0 1.4e-13 51.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM63501.1 - 9.4e-11 42.7 0.0 9.8e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM63501.1 - 8.3e-07 28.5 0.0 1e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KFM63501.1 - 0.029 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase bMG10 PF17973.1 KFM63501.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain Thioesterase PF00975.20 KFM63501.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Ndr PF03096.14 KFM63501.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.6 1 1 0 1 1 1 0 Ndr family PAF-AH_p_II PF03403.13 KFM63501.1 - 0.15 10.5 0.0 0.58 8.6 0.0 1.8 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Troponin PF00992.20 KFM63502.1 - 7.9e-07 29.4 10.5 7.9e-07 29.4 10.5 4.2 3 1 1 4 4 4 2 Troponin HTH_Tnp_Tc3_2 PF01498.18 KFM63503.1 - 7.7e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63503.1 - 1.8e-15 56.9 0.1 1.6e-14 53.9 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM63503.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63503.1 - 0.0025 17.6 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63503.1 - 0.013 15.6 0.1 0.066 13.4 0.1 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM63503.1 - 0.03 14.3 2.6 0.036 14.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM63503.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Hydrolase_4 PF12146.8 KFM63504.1 - 0.098 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFM63505.1 - 1.2e-05 24.5 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 KFM63505.1 - 0.00029 20.6 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold QVR PF17064.5 KFM63506.1 - 5.6e-17 61.8 2.8 6.3e-17 61.6 2.8 1.1 1 0 0 1 1 1 1 Sleepless protein PRE_C2HC PF07530.11 KFM63507.1 - 2.1e-05 24.6 0.1 2.8e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Associated with zinc fingers UQ_con PF00179.26 KFM63508.1 - 2.7e-47 160.0 0.0 3e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM63508.1 - 0.0037 17.0 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFM63508.1 - 0.0087 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KFM63508.1 - 0.04 14.2 0.1 0.062 13.6 0.1 1.4 1 1 0 1 1 1 0 RWD domain Caveolin PF01146.17 KFM63509.1 - 7.2e-43 145.7 1.7 1e-42 145.3 1.7 1.1 1 0 0 1 1 1 1 Caveolin GON PF08685.11 KFM63510.1 - 7.4e-21 74.9 0.0 7.9e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 GON domain Ras PF00071.22 KFM63511.1 - 1.7e-63 213.0 0.3 2e-63 212.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM63511.1 - 7e-36 123.1 0.2 1.1e-35 122.5 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM63511.1 - 7.8e-14 51.5 0.2 1e-13 51.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM63511.1 - 8.4e-07 29.1 0.1 1.3e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFM63511.1 - 3e-05 24.3 0.3 0.00049 20.4 0.1 2.3 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KFM63511.1 - 3.3e-05 23.5 0.4 0.00016 21.3 0.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM63511.1 - 0.00021 21.2 0.3 0.081 12.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFM63511.1 - 0.0012 18.2 0.1 0.0023 17.3 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM63511.1 - 0.0016 17.9 0.0 0.0037 16.7 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KFM63511.1 - 0.0016 18.9 0.2 0.0032 17.9 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 KFM63511.1 - 0.0023 17.7 0.0 0.0061 16.3 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KFM63511.1 - 0.012 15.1 0.2 0.036 13.6 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 KFM63511.1 - 0.014 15.1 0.1 0.047 13.4 0.0 1.7 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFM63511.1 - 0.019 15.2 0.5 0.65 10.2 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFM63511.1 - 0.024 14.7 0.1 0.073 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KFM63511.1 - 0.028 13.9 0.1 0.12 11.8 0.0 2.0 2 1 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 KFM63511.1 - 0.061 13.8 0.2 0.091 13.3 0.2 1.6 1 1 0 1 1 1 0 ABC transporter FAD-SLDH PF12318.8 KFM63511.1 - 0.084 12.9 0.4 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_7 PF12775.7 KFM63511.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KFM63511.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KFM63511.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_21 PF13304.6 KFM63511.1 - 0.16 11.8 0.9 0.25 11.1 0.5 1.8 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KFM63511.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Epimerase PF01370.21 KFM63512.1 - 8.2e-22 77.8 0.0 1.1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM63512.1 - 6e-11 41.9 0.0 1.3e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFM63512.1 - 3.7e-09 36.1 0.0 6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFM63512.1 - 2.8e-08 33.9 0.0 4.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFM63512.1 - 2.8e-08 33.5 0.0 4.9e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFM63512.1 - 0.00012 21.3 0.1 0.00068 18.9 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KFM63512.1 - 0.0012 19.1 0.0 0.0033 17.7 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KFM63512.1 - 0.032 13.4 0.1 2.6 7.1 0.0 2.8 2 1 0 2 2 2 0 Male sterility protein L_protein_N PF15518.6 KFM63512.1 - 0.043 13.6 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 L protein N-terminus DUF2922 PF11148.8 KFM63512.1 - 0.051 13.3 0.0 0.87 9.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) TetR_C_10 PF16295.5 KFM63512.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Methyltransf_34 PF11312.8 KFM63513.1 - 0.00026 20.4 0.0 0.00084 18.7 0.0 1.9 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase Methyltransf_34 PF11312.8 KFM63514.1 - 8.5e-07 28.5 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase GntP_permease PF02447.16 KFM63514.1 - 0.086 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 GntP family permease Peptidase_M14 PF00246.24 KFM63515.1 - 6.2e-26 91.9 0.0 7.3e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFM63517.1 - 1.2e-10 41.6 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Carboxypeptidase activation peptide zf-CCHC PF00098.23 KFM63518.1 - 1.4e-10 40.8 8.9 1.4e-05 25.0 0.9 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFM63518.1 - 2e-09 37.1 8.7 3e-05 23.8 1.7 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KFM63518.1 - 0.00014 21.5 4.8 0.039 13.7 0.6 2.6 2 0 0 2 2 2 2 Zinc knuckle DUF4407 PF14362.6 KFM63518.1 - 0.0015 18.0 0.5 0.0019 17.6 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HscB_4_cys PF18256.1 KFM63518.1 - 0.042 13.6 11.3 0.54 10.1 1.7 2.6 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Mu-like_Com PF10122.9 KFM63518.1 - 0.07 12.6 0.5 0.07 12.6 0.5 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com HSBP1 PF06825.12 KFM63518.1 - 0.11 12.3 0.5 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF2703 PF10865.8 KFM63518.1 - 0.33 11.1 3.7 3.5 7.8 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) Stc1 PF12898.7 KFM63518.1 - 0.36 11.4 9.0 7.3 7.2 6.4 2.2 1 1 1 2 2 2 0 Stc1 domain zf-C2H2_10 PF16588.5 KFM63518.1 - 0.51 10.1 9.1 2.1 8.2 0.6 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger zf-FCS PF06467.14 KFM63518.1 - 0.54 10.2 7.7 3.4 7.7 1.5 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.6 KFM63518.1 - 2.9 7.4 6.9 0.61 9.6 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain PIG-U PF06728.13 KFM63519.1 - 1.3e-71 241.7 41.9 1.5e-71 241.5 41.9 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U HSF_DNA-bind PF00447.17 KFM63521.1 - 4.7e-32 110.5 3.1 4.7e-32 110.5 3.1 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding Ets PF00178.22 KFM63521.1 - 0.0061 17.0 2.0 0.012 16.1 0.2 2.4 1 1 1 2 2 2 1 Ets-domain Cep57_CLD_2 PF14197.6 KFM63521.1 - 0.1 12.7 2.1 11 6.2 0.8 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 HTH_Tnp_Tc3_2 PF01498.18 KFM63522.1 - 2.2e-19 69.5 3.6 5.5e-19 68.2 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63522.1 - 4.5e-16 58.9 0.0 2.2e-15 56.7 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM63522.1 - 3.5e-07 30.7 2.0 3.5e-07 30.7 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KFM63522.1 - 4.9e-07 29.7 1.2 0.00017 21.6 0.1 2.7 3 0 0 3 3 2 2 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM63522.1 - 1.1e-06 28.7 2.4 8.6e-05 22.6 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM63522.1 - 2.7e-06 27.3 0.7 3.9e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KFM63522.1 - 6.1e-06 25.9 3.8 6.4e-05 22.6 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM63522.1 - 7e-05 22.6 0.6 0.0011 18.9 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM63522.1 - 0.0011 18.9 0.4 0.016 15.1 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM63522.1 - 0.041 13.5 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_17 PF12728.7 KFM63522.1 - 0.086 13.0 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 KFM63522.1 - 0.098 12.7 0.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 KFM63522.1 - 0.16 12.0 0.1 29 4.8 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM63522.1 - 0.28 11.0 3.9 1.4 8.8 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM63522.1 - 0.74 9.3 3.3 5.4 6.5 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.6 KFM63523.1 - 1.1e-05 25.2 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63524.1 - 1.4e-08 34.8 4.5 5.3e-08 33.0 1.9 2.6 2 1 0 2 2 2 1 Transposase MarR_2 PF12802.7 KFM63524.1 - 0.00011 22.1 0.5 0.0048 16.8 0.1 2.5 2 0 0 2 2 2 1 MarR family PAX PF00292.18 KFM63524.1 - 0.00034 20.5 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFM63524.1 - 0.0048 16.7 0.1 0.019 14.7 0.1 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM63524.1 - 0.0072 16.3 0.1 0.019 14.9 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 KFM63524.1 - 0.024 14.4 0.2 0.096 12.5 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_32 PF13565.6 KFM63524.1 - 0.041 14.5 0.5 0.041 14.5 0.5 2.5 1 1 1 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.6 KFM63524.1 - 0.046 13.5 0.1 1.1 9.0 0.1 2.3 1 1 0 1 1 1 0 DDE superfamily endonuclease HTH_3 PF01381.22 KFM63524.1 - 0.15 12.1 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix TrmB PF01978.19 KFM63524.1 - 0.17 11.8 0.0 0.49 10.3 0.0 1.7 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB PAN_1 PF00024.26 KFM63525.1 - 2.2e-07 30.8 0.5 2.2e-07 30.8 0.5 2.1 1 1 1 2 2 2 1 PAN domain EGF PF00008.27 KFM63525.1 - 0.0014 18.9 10.9 0.0014 18.9 10.9 3.6 4 0 0 4 4 4 1 EGF-like domain PAN_4 PF14295.6 KFM63525.1 - 0.0056 16.6 3.6 0.0056 16.6 3.6 2.4 1 1 1 2 2 2 1 PAN domain DEAD_2 PF06733.15 KFM63527.1 - 5.5e-51 172.7 0.1 1.1e-50 171.6 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KFM63527.1 - 1.4e-44 152.1 1.4 5.1e-40 137.2 0.4 2.8 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KFM63527.1 - 6.1e-44 150.2 0.1 2.7e-43 148.1 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KFM63527.1 - 2.6e-07 30.8 0.0 7.4e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM63527.1 - 0.00093 19.0 0.1 1.6 8.5 0.1 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 KFM63527.1 - 0.029 14.6 0.4 5.7 7.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Radical_SAM_C PF16199.5 KFM63527.1 - 0.067 13.2 0.1 9.8 6.3 0.0 2.7 2 0 0 2 2 2 0 Radical_SAM C-terminal domain SNF2_N PF00176.23 KFM63527.1 - 0.071 11.8 0.2 4 6.1 0.1 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain HMG_box PF00505.19 KFM63528.1 - 3.6e-18 65.7 1.2 7.5e-18 64.7 1.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM63528.1 - 2.3e-07 31.3 0.5 4.2e-07 30.5 0.5 1.5 1 0 0 1 1 1 1 HMG-box domain HTH_Tnp_Tc3_2 PF01498.18 KFM63529.1 - 2.1e-16 59.9 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63529.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease UbiA PF01040.18 KFM63531.1 - 6.2e-34 117.4 6.1 7.3e-34 117.2 6.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosomal_L21e PF01157.18 KFM63532.1 - 6.7e-48 160.7 6.3 6.7e-48 160.7 6.3 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e FAT PF02259.23 KFM63533.1 - 2.6e-111 372.2 6.9 2.6e-111 372.2 6.9 2.4 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KFM63533.1 - 2.3e-77 260.2 1.7 2.4e-77 260.1 0.4 1.8 2 0 0 2 2 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KFM63533.1 - 2.1e-59 200.0 6.9 2.9e-52 176.8 0.6 5.1 4 0 0 4 4 4 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KFM63533.1 - 1.5e-44 150.4 11.7 2.8e-44 149.6 0.4 4.9 3 1 1 4 4 4 1 FKBP12-rapamycin binding domain FATC PF02260.20 KFM63533.1 - 1e-17 63.6 0.3 2.2e-17 62.5 0.3 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KFM63533.1 - 3.3e-12 46.6 0.8 0.0055 17.1 0.0 7.6 8 1 0 8 8 6 2 HEAT repeats HEAT_EZ PF13513.6 KFM63533.1 - 1.2e-10 41.7 17.2 0.046 14.2 0.0 10.9 11 2 2 13 13 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFM63533.1 - 7.6e-09 36.1 5.7 0.11 13.1 0.3 7.5 5 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KFM63533.1 - 5.2e-05 23.2 19.6 0.021 15.1 0.0 9.5 12 0 0 12 12 10 2 HEAT repeat IFRD PF05004.13 KFM63533.1 - 0.00012 21.3 0.4 0.21 10.6 0.0 3.9 5 0 0 5 5 5 1 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 KFM63533.1 - 0.0033 17.0 5.6 0.28 10.7 0.1 4.6 2 1 3 5 5 5 1 Tti2 family Adaptin_N PF01602.20 KFM63533.1 - 0.019 13.6 9.9 8.9 4.7 0.0 6.2 5 2 1 7 7 7 0 Adaptin N terminal region TPR_16 PF13432.6 KFM63533.1 - 0.022 15.4 0.2 0.56 10.9 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM63533.1 - 0.029 14.1 0.9 0.097 12.4 0.9 1.9 1 0 0 1 1 1 0 TPR repeat TPR_19 PF14559.6 KFM63533.1 - 0.034 14.7 2.4 0.13 12.8 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat UME PF08064.13 KFM63533.1 - 0.065 13.2 7.7 4.3 7.3 0.2 5.7 7 0 0 7 7 5 0 UME (NUC010) domain ANAPC3 PF12895.7 KFM63533.1 - 0.071 13.3 0.3 34 4.7 0.0 3.9 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KFM63533.1 - 0.072 13.0 5.8 0.044 13.6 1.2 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat RICTOR_V PF14668.6 KFM63533.1 - 0.072 13.3 0.0 0.6 10.4 0.0 2.7 2 0 0 2 2 1 0 Rapamycin-insensitive companion of mTOR, domain 5 RNase_H2-Ydr279 PF09468.10 KFM63533.1 - 0.086 13.0 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain TPR_15 PF13429.6 KFM63533.1 - 0.14 11.3 5.7 0.1 11.8 2.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM63533.1 - 0.25 11.6 8.5 0.077 13.1 0.8 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM63533.1 - 3.3 8.8 8.0 4.9 8.2 0.2 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.23 KFM63534.1 - 1.3e-15 57.1 0.3 1.6e-15 56.8 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KFM63534.1 - 9.1e-10 38.9 0.4 1.8e-08 34.7 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KFM63534.1 - 0.0094 15.6 1.2 0.24 11.0 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases HTH_Tnp_Tc3_2 PF01498.18 KFM63536.1 - 7.7e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63536.1 - 4.5e-15 55.7 0.1 5.2e-14 52.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM63536.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63536.1 - 0.0025 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63536.1 - 0.017 15.3 0.1 0.063 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM63536.1 - 0.034 14.2 0.4 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DUF4209 PF13910.6 KFM63537.1 - 0.18 12.0 1.4 1.6 9.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4209) DUF3697 PF12478.8 KFM63538.1 - 2e-16 59.8 1.0 4.9e-16 58.5 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 DUF1296 PF06972.11 KFM63538.1 - 0.0028 17.8 0.1 0.0072 16.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) DUF3580 PF12117.8 KFM63538.1 - 0.047 13.9 0.1 0.047 13.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) DUF1295 PF06966.12 KFM63539.1 - 3.1e-41 141.4 0.0 3.5e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KFM63539.1 - 9.5e-05 22.4 1.8 0.00021 21.3 1.8 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KFM63539.1 - 0.00035 20.9 0.3 0.0023 18.3 0.0 2.2 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KFM63539.1 - 0.00045 20.6 0.3 0.00093 19.6 0.3 1.6 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KFM63539.1 - 0.0015 17.4 0.1 0.0018 17.1 0.1 1.2 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family HTH_Tnp_Tc3_2 PF01498.18 KFM63540.1 - 1.7e-16 60.2 2.2 3.2e-16 59.3 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63540.1 - 0.00017 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Lys PF00062.20 KFM63541.1 - 1.4e-25 89.9 2.3 1.6e-25 89.7 2.3 1.1 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.20 KFM63541.1 - 0.031 13.9 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain DUF4371 PF14291.6 KFM63542.1 - 7.2e-05 22.5 0.3 0.00051 19.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KFM63542.1 - 9.3e-05 22.3 0.2 0.00025 21.0 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 KFM63542.1 - 0.003 17.5 0.1 0.0073 16.3 0.1 1.6 1 0 0 1 1 1 1 BED zinc finger Ferrochelatase PF00762.19 KFM63546.1 - 9e-54 182.7 0.0 1.1e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Ferrochelatase PF00762.19 KFM63547.1 - 5.4e-30 104.5 0.0 6.5e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CRISPR_Cas9_WED PF18061.1 KFM63547.1 - 0.098 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain DnaJ PF00226.31 KFM63548.1 - 2.8e-24 85.0 1.8 6.4e-24 83.9 1.8 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KFM63548.1 - 9.2e-21 74.5 0.0 1.4e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFM63548.1 - 1.7e-08 34.7 18.7 3.4e-08 33.7 18.7 1.6 1 0 0 1 1 1 1 DnaJ central domain RseC_MucC PF04246.12 KFM63548.1 - 0.035 14.1 1.5 0.035 14.1 1.5 1.9 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Anti-TRAP PF15777.5 KFM63548.1 - 6.6 6.8 16.3 0.2 11.7 1.1 3.3 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-A20 PF01754.16 KFM63549.1 - 6.1e-13 48.4 6.8 6.1e-13 48.4 6.8 2.2 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 KFM63549.1 - 3.5e-09 36.7 10.3 3.5e-09 36.7 10.3 2.1 2 1 1 3 3 3 1 AN1-like Zinc finger Ndc1_Nup PF09531.10 KFM63549.1 - 1.1 7.8 2.6 1.3 7.7 2.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 KFM63549.1 - 3.6 6.1 9.9 4.1 5.9 9.9 1.0 1 0 0 1 1 1 0 Hamartin protein Herpes_BLLF1 PF05109.13 KFM63549.1 - 4.3 5.2 15.8 5.4 4.9 15.8 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DDE_1 PF03184.19 KFM63550.1 - 1.3e-41 142.2 0.1 2.3e-41 141.3 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM63550.1 - 5.3e-15 55.2 0.3 1.7e-14 53.6 0.3 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM63550.1 - 3.9e-05 23.2 2.0 0.00015 21.4 2.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_psq PF05225.16 KFM63550.1 - 0.018 14.8 0.0 0.056 13.2 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain ErmC PF06308.11 KFM63550.1 - 0.026 14.9 0.2 0.081 13.3 0.2 1.8 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) HTH_23 PF13384.6 KFM63550.1 - 0.039 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 KFM63550.1 - 0.16 12.3 0.6 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Transposase Ldl_recept_a PF00057.18 KFM63554.1 - 6e-17 61.6 35.1 1.3e-10 41.3 7.3 3.6 3 1 0 3 3 3 2 Low-density lipoprotein receptor domain class A SEA PF01390.20 KFM63554.1 - 1.7e-13 50.5 0.0 2.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 SEA domain Ig_3 PF13927.6 KFM63555.1 - 1.3e-10 41.7 0.0 3.9e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM63555.1 - 3e-10 40.0 0.0 1.1e-09 38.2 0.0 1.9 2 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFM63555.1 - 4.4e-08 33.2 0.0 2e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM63555.1 - 7.4e-08 32.6 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFM63555.1 - 0.0028 18.0 0.8 0.02 15.2 0.3 2.2 2 0 0 2 2 2 1 Fibronectin type III domain V-set PF07686.17 KFM63555.1 - 0.085 13.0 0.1 0.32 11.2 0.0 2.1 1 1 1 2 2 2 0 Immunoglobulin V-set domain HicB_lk_antitox PF15919.5 KFM63555.1 - 0.11 12.7 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Ig_6 PF18452.1 KFM63555.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain TIM PF00121.18 KFM63557.1 - 0.041 13.2 0.0 0.041 13.2 0.0 1.0 1 0 0 1 1 1 0 Triosephosphate isomerase HTH_Tnp_Tc3_2 PF01498.18 KFM63559.1 - 4.8e-16 58.8 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63559.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63559.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63559.1 - 0.0027 17.5 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63559.1 - 2.3 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63561.1 - 1.8e-16 60.2 2.2 3.9e-16 59.1 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63561.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Complex1_LYR PF05347.15 KFM63562.1 - 3.4e-16 59.0 0.1 5.2e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFM63562.1 - 0.00044 20.9 0.2 0.00054 20.7 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KFM63562.1 - 0.0032 18.0 0.0 0.0045 17.6 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like HARP PF07443.13 KFM63562.1 - 0.091 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 HepA-related protein (HARP) 14-3-3 PF00244.20 KFM63563.1 - 1.9e-50 171.4 3.6 2.1e-50 171.3 3.6 1.0 1 0 0 1 1 1 1 14-3-3 protein CREPT PF16566.5 KFM63563.1 - 0.32 11.1 3.5 7.3 6.8 0.3 2.1 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour C2 PF00168.30 KFM63564.1 - 4.4e-44 149.0 0.0 1.8e-22 79.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 KFM63564.1 - 2e-20 73.2 3.4 4.8e-20 71.9 3.4 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger PI3K_C2 PF00792.24 KFM63564.1 - 0.071 13.0 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 zf-piccolo PF05715.13 KFM63564.1 - 0.82 9.9 7.4 2.6 8.3 7.4 1.9 1 0 0 1 1 1 0 Piccolo Zn-finger FYVE PF01363.21 KFM63564.1 - 1.4 9.1 6.0 5.4 7.2 6.0 2.0 1 0 0 1 1 1 0 FYVE zinc finger 7tm_1 PF00001.21 KFM63566.1 - 0.082 12.2 0.0 0.086 12.2 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KFM63567.1 - 5.3e-17 62.0 2.4 6.5e-17 61.7 2.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFM63567.1 - 4.4e-05 22.9 1.8 5.5e-05 22.6 1.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw ETRAMP PF09716.10 KFM63567.1 - 5.7 7.1 6.0 5.3 7.2 3.5 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) HTH_Tnp_Tc3_2 PF01498.18 KFM63568.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63568.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63568.1 - 1.9e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63568.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63568.1 - 0.027 14.6 0.4 0.085 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM63568.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RAWUL PF16207.5 KFM63569.1 - 3.9e-18 65.9 0.1 8.2e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFM63569.1 - 5.6e-10 38.9 6.2 5.6e-10 38.9 6.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM63569.1 - 1.3e-09 37.7 7.1 3.9e-09 36.2 7.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM63569.1 - 3.2e-06 27.4 6.7 1.1e-05 25.7 6.7 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM63569.1 - 5.5e-05 23.1 7.2 0.00014 21.7 7.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM63569.1 - 7.9e-05 22.4 7.2 0.00018 21.3 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM63569.1 - 0.00016 21.9 4.5 0.00071 19.8 4.5 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM63569.1 - 0.00068 19.6 4.8 0.0028 17.6 4.8 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 KFM63569.1 - 0.0062 16.3 3.4 0.019 14.8 3.4 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KFM63569.1 - 0.013 15.3 5.9 0.029 14.2 5.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFM63569.1 - 0.06 13.5 5.4 0.14 12.3 5.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KFM63569.1 - 0.086 13.0 9.1 0.22 11.7 9.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad60-SLD PF11976.8 KFM63569.1 - 0.097 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like zf-RING_4 PF14570.6 KFM63569.1 - 0.26 11.1 2.8 0.7 9.7 2.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KFM63569.1 - 3.5 7.4 5.8 7.2 6.4 5.8 1.4 1 0 0 1 1 1 0 P-11 zinc finger Transposase_1 PF01359.18 KFM63570.1 - 1.3e-09 37.7 0.1 3.4e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM63570.1 - 7.5e-07 29.2 0.1 1.4e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_28 PF13518.6 KFM63570.1 - 0.0014 18.7 0.3 2.1 8.6 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 KFM63570.1 - 0.0017 18.2 0.2 0.0048 16.8 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_29 PF13551.6 KFM63570.1 - 0.0018 18.3 0.3 2.9 8.0 0.0 2.6 2 0 0 2 2 2 2 Winged helix-turn helix HTH_32 PF13565.6 KFM63570.1 - 0.0043 17.6 2.5 0.0074 16.9 0.9 2.3 1 1 2 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 KFM63570.1 - 0.0046 16.5 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r3 PF04539.16 KFM63570.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 Sigma-70 region 3 HTH_Tnp_Tc3_2 PF01498.18 KFM63570.1 - 0.06 13.6 0.2 0.17 12.1 0.2 1.9 1 1 0 1 1 1 0 Transposase HTH_41 PF14502.6 KFM63570.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SpoIIID PF12116.8 KFM63570.1 - 0.18 11.9 1.1 0.48 10.5 0.1 2.1 3 0 0 3 3 3 0 Stage III sporulation protein D HTH_23 PF13384.6 KFM63570.1 - 0.48 10.3 3.2 6.5 6.7 0.1 2.8 2 1 0 2 2 2 0 Homeodomain-like domain DUF659 PF04937.15 KFM63571.1 - 0.0084 16.0 0.7 0.011 15.6 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-C2H2 PF00096.26 KFM63572.1 - 1.3e-17 63.1 30.2 7.6e-06 26.1 3.7 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63572.1 - 6.3e-14 51.5 28.4 0.00023 21.7 3.5 4.4 4 1 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM63572.1 - 3.9e-11 42.9 31.4 0.00019 21.6 2.0 5.2 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM63572.1 - 9.4e-06 25.5 27.1 0.00013 21.9 5.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM63572.1 - 1.6e-05 25.1 45.5 0.12 12.9 1.3 5.4 5 1 0 5 5 5 4 Zinc-finger double domain zf-met PF12874.7 KFM63572.1 - 1.7e-05 25.0 29.5 7.4e-05 23.0 1.7 4.7 4 1 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFM63572.1 - 6.6e-05 23.3 31.9 0.25 11.8 4.9 3.7 2 1 1 3 3 3 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFM63572.1 - 0.0003 21.1 34.5 0.18 12.2 6.3 4.0 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM63572.1 - 0.2 11.6 12.8 0.3 11.0 0.9 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM63572.1 - 0.45 10.5 0.2 0.45 10.5 0.2 3.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM63572.1 - 0.58 10.3 10.2 3.3 7.9 0.2 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) PyrI_C PF02748.15 KFM63572.1 - 0.76 9.7 20.4 0.45 10.5 5.9 3.7 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KFM63572.1 - 1 10.2 18.8 1.8 9.4 4.2 2.3 1 1 0 2 2 2 0 zinc-ribbon family PseudoU_synth_2 PF00849.22 KFM63572.1 - 1.1 9.4 7.4 0.13 12.3 2.9 1.6 2 0 0 2 2 2 0 RNA pseudouridylate synthase Ribosomal_S15 PF00312.22 KFM63572.1 - 2.8 8.2 9.6 12 6.1 2.8 3.0 2 1 0 2 2 2 0 Ribosomal protein S15 DZR PF12773.7 KFM63572.1 - 6.7 6.8 17.4 2.6e+02 1.8 0.5 3.1 1 1 1 2 2 2 0 Double zinc ribbon HTH_Tnp_Tc3_2 PF01498.18 KFM63573.1 - 0.03 14.6 0.2 0.042 14.1 0.2 1.2 1 0 0 1 1 1 0 Transposase zf-C2H2 PF00096.26 KFM63574.1 - 4.7e-18 64.6 28.7 4.8e-07 29.9 2.2 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63574.1 - 7.3e-15 54.4 29.0 0.00024 21.7 2.1 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM63574.1 - 8.7e-11 41.8 24.5 7.3e-05 22.9 1.7 5.1 4 2 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM63574.1 - 1.7e-08 34.3 18.7 0.0049 16.8 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM63574.1 - 3.9e-07 30.2 40.3 0.011 16.1 5.3 5.8 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_2 PF12756.7 KFM63574.1 - 8.4e-06 26.1 23.0 0.11 12.8 0.4 4.0 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFM63574.1 - 2e-05 24.9 20.5 0.0078 16.6 1.3 3.4 2 1 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 KFM63574.1 - 0.00046 20.0 9.2 0.2 11.6 0.7 3.5 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf-met PF12874.7 KFM63574.1 - 0.0021 18.4 27.1 0.028 14.8 0.9 4.9 4 2 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 KFM63574.1 - 0.0069 16.2 8.3 0.032 14.1 0.3 3.3 3 0 0 3 3 3 1 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KFM63574.1 - 0.097 13.2 22.6 0.18 12.3 0.7 4.7 4 1 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-BED PF02892.15 KFM63574.1 - 0.21 11.7 21.5 8.5 6.5 3.0 4.0 1 1 2 3 3 3 0 BED zinc finger FYDLN_acid PF09538.10 KFM63574.1 - 1.2 9.9 5.2 15 6.3 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_15 PF17032.5 KFM63574.1 - 1.3 9.8 17.9 0.23 12.2 5.6 2.4 1 1 2 3 3 3 0 zinc-ribbon family DUF2256 PF10013.9 KFM63574.1 - 2.5 8.3 13.2 16 5.7 0.6 3.5 4 0 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_ZIC PF18366.1 KFM63574.1 - 3 8.0 10.0 0.57 10.3 1.4 3.1 2 2 1 3 3 3 0 Zic proteins zinc finger domain DZR PF12773.7 KFM63574.1 - 7 6.8 18.3 4.3e+02 1.0 18.3 3.0 1 1 0 1 1 1 0 Double zinc ribbon TAFII55_N PF04658.13 KFM63575.1 - 3.3e-55 186.2 0.4 1.1e-54 184.5 0.4 1.9 1 0 0 1 1 1 1 TAFII55 protein conserved region PfkB PF00294.24 KFM63576.1 - 1.3e-67 228.2 0.8 1.5e-67 228.1 0.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFM63576.1 - 9e-05 22.0 0.1 0.00022 20.7 0.1 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Phosphorylase PF00343.20 KFM63577.1 - 0 1044.8 0.1 0 1044.4 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase PTS_EIIA_2 PF00359.22 KFM63577.1 - 0.11 12.4 0.1 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF4764 PF15961.5 KFM63580.1 - 1.5e-09 37.2 7.5 1.5e-09 37.2 7.5 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4764) AT_hook PF02178.19 KFM63580.1 - 0.12 12.3 3.2 0.35 10.9 3.2 1.8 1 0 0 1 1 1 0 AT hook motif Synuclein PF01387.17 KFM63580.1 - 5.2 7.3 6.4 0.77 10.0 1.0 2.4 2 1 1 3 3 3 0 Synuclein RtcR PF06956.11 KFM63581.1 - 0.06 12.8 0.1 0.066 12.6 0.1 1.1 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase HTH_Tnp_Tc3_2 PF01498.18 KFM63584.1 - 4.2e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63584.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63584.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63584.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63584.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain BCAS2 PF05700.11 KFM63587.1 - 0.0014 18.4 1.4 0.0032 17.2 1.4 1.6 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) FapA PF03961.13 KFM63587.1 - 0.031 12.9 0.2 0.045 12.3 0.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1492 PF07374.11 KFM63587.1 - 0.054 13.7 1.6 2.5 8.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Tweety PF04906.13 KFM63587.1 - 0.062 12.0 0.4 1.2 7.7 0.4 2.1 2 0 0 2 2 2 0 Tweety Apelin PF15360.6 KFM63587.1 - 2.2 8.9 6.1 2.6 8.7 4.0 2.2 2 0 0 2 2 2 0 APJ endogenous ligand LMBR1 PF04791.16 KFM63587.1 - 2.5 6.9 7.7 0.69 8.7 4.5 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein CRAL_TRIO PF00650.20 KFM63588.1 - 3.2e-18 66.0 0.0 4.5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM63588.1 - 0.00082 19.9 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 KFM63589.1 - 0.00015 21.9 1.1 0.0003 20.9 1.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Complex1_LYR_1 PF13232.6 KFM63589.1 - 0.014 15.9 0.2 0.016 15.8 0.2 1.4 1 1 0 1 1 1 0 Complex1_LYR-like RETICULATA-like PF11891.8 KFM63589.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein RETICULATA-related CRAL_TRIO PF00650.20 KFM63590.1 - 2.5e-25 89.0 0.1 3.9e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain zf_Hakai PF18408.1 KFM63590.1 - 0.068 12.9 0.9 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain V-SNARE PF05008.15 KFM63592.1 - 9.7e-11 41.9 1.5 9.7e-11 41.9 1.5 1.6 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KFM63592.1 - 5.1e-08 33.1 1.0 1e-07 32.1 1.0 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus WD40 PF00400.32 KFM63596.1 - 5.8e-15 55.4 13.5 0.0032 18.3 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat HEAT PF02985.22 KFM63596.1 - 4.5e-13 48.2 0.2 0.00021 21.3 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KFM63596.1 - 9.4e-12 45.2 0.1 2.2e-07 31.2 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KFM63596.1 - 5.3e-07 30.0 0.0 0.0015 19.0 0.0 2.8 2 0 0 2 2 2 2 HEAT-like repeat ANAPC4_WD40 PF12894.7 KFM63596.1 - 8.7e-07 29.2 0.1 0.32 11.3 0.0 4.8 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 KFM63596.1 - 8e-05 22.7 0.0 0.00057 20.0 0.0 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.7 KFM63596.1 - 0.051 13.5 0.0 0.24 11.3 0.0 2.1 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus RTP1_C1 PF10363.9 KFM63596.1 - 0.18 12.0 0.0 4.8 7.4 0.0 3.0 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Raptor_N PF14538.6 KFM63597.1 - 8.7e-72 239.9 0.0 1.5e-71 239.1 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DUF5094 PF17015.5 KFM63600.1 - 0.41 10.7 3.4 0.86 9.7 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) HTH_Tnp_Tc3_2 PF01498.18 KFM63601.1 - 3.8e-05 23.9 0.7 3.8e-05 23.9 0.7 1.6 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM63601.1 - 0.013 15.3 0.3 0.29 11.0 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM63601.1 - 0.1 12.4 4.3 0.2 11.5 0.1 2.8 2 2 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.6 KFM63601.1 - 0.15 12.7 6.4 0.068 13.8 3.1 1.9 1 1 1 2 2 2 0 Homeodomain-like domain SIR2 PF02146.17 KFM63602.1 - 1.1e-61 207.9 0.0 1.6e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KFM63602.1 - 0.0011 18.8 0.4 0.0027 17.5 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KFM63602.1 - 0.0098 15.6 0.0 4.8 6.9 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Bacteroid_pep PF14406.6 KFM63602.1 - 0.14 12.5 0.3 0.39 11.1 0.3 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes Spaetzle PF16077.5 KFM63603.1 - 3.2e-21 75.7 0.2 3.2e-21 75.7 0.2 2.0 2 0 0 2 2 2 1 Spaetzle zf-C2H2 PF00096.26 KFM63604.1 - 1.3e-21 75.7 37.3 7.2e-07 29.3 0.4 5.5 6 0 0 6 6 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM63604.1 - 6.5e-20 70.6 41.4 4e-10 39.6 1.3 6.9 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM63604.1 - 3.5e-16 58.5 32.0 0.00053 20.6 2.0 5.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM63604.1 - 3.4e-12 46.3 25.0 0.00034 20.8 0.6 5.1 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM63604.1 - 1.5e-11 44.3 21.8 0.02 15.3 0.9 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM63604.1 - 2.8e-11 43.1 27.1 0.00053 19.9 0.3 4.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2HE PF16278.5 KFM63604.1 - 2.3e-07 31.2 25.9 0.036 14.5 1.6 4.6 1 1 4 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 KFM63604.1 - 0.00029 20.6 15.4 0.7 9.8 0.3 4.9 3 1 2 5 5 5 2 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 KFM63604.1 - 0.00039 20.1 30.3 0.0037 17.0 1.1 4.9 5 0 0 5 5 4 3 C2H2-type zinc-finger domain BolA PF01722.18 KFM63604.1 - 0.0035 17.6 1.4 2.6 8.4 0.3 3.5 1 1 2 3 3 3 1 BolA-like protein GAGA PF09237.11 KFM63604.1 - 0.0038 17.0 8.6 2.2 8.1 1.9 3.9 1 1 3 4 4 4 2 GAGA factor zf-C2H2_2 PF12756.7 KFM63604.1 - 0.0069 16.7 29.7 0.19 12.1 1.4 5.2 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFM63604.1 - 0.041 13.7 35.5 0.17 11.7 2.2 5.4 6 0 0 6 6 5 0 zinc-finger C2H2-type zinc_ribbon_2 PF13240.6 KFM63604.1 - 0.075 12.8 0.4 0.075 12.8 0.4 5.0 5 0 0 5 5 5 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 KFM63604.1 - 0.08 12.9 21.7 0.52 10.3 0.7 5.7 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-Paramyx-P PF13008.7 KFM63604.1 - 0.11 11.9 0.4 0.11 11.9 0.4 3.7 4 0 0 4 4 3 0 Zinc-binding domain of Paramyxoviridae V protein zf-ribbon_3 PF13248.6 KFM63604.1 - 0.18 11.3 0.1 0.18 11.3 0.1 4.9 6 1 0 6 6 5 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFM63604.1 - 0.29 11.2 23.4 1.4 8.9 3.4 4.7 1 1 2 3 3 2 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KFM63604.1 - 0.41 10.8 29.3 4 7.6 0.6 5.8 2 1 3 5 5 4 0 Zinc ribbon domain DUF1272 PF06906.11 KFM63604.1 - 0.45 10.6 0.2 0.45 10.6 0.2 4.2 3 1 2 5 5 4 0 Protein of unknown function (DUF1272) Zn_Tnp_IS1595 PF12760.7 KFM63604.1 - 0.48 10.4 0.1 0.48 10.4 0.1 3.7 2 1 2 4 4 2 0 Transposase zinc-ribbon domain PknG_rubred PF16919.5 KFM63604.1 - 0.53 10.4 10.1 6.1 7.0 0.0 4.5 1 1 4 5 5 5 0 Protein kinase G rubredoxin domain zf_UBZ PF18439.1 KFM63604.1 - 0.77 9.4 15.9 14 5.4 0.8 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-DBF PF07535.12 KFM63604.1 - 1.7 8.8 14.1 9.7 6.4 0.0 4.3 4 0 0 4 4 4 0 DBF zinc finger zf-BED PF02892.15 KFM63604.1 - 4 7.6 31.4 1.8 8.7 1.9 4.5 3 2 0 3 3 3 0 BED zinc finger zf-RRPl_C4 PF17026.5 KFM63604.1 - 5.4 7.2 22.0 0.31 11.2 9.4 3.0 2 1 1 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type YacG PF03884.14 KFM63604.1 - 5.8 6.7 12.4 6.6 6.5 5.1 3.7 3 1 0 3 3 3 0 DNA gyrase inhibitor YacG zf-MYST PF17772.1 KFM63604.1 - 8.5 6.1 13.0 12 5.6 0.2 3.7 3 1 1 4 4 4 0 MYST family zinc finger domain DpnI PF06044.12 KFM63604.1 - 8.6 6.0 18.4 1.3 8.6 1.8 3.2 2 1 0 3 3 3 0 Dam-replacing family Rabaptin PF03528.15 KFM63605.1 - 3.6e-23 82.0 16.4 3.8e-13 49.0 0.3 2.0 2 0 0 2 2 2 2 Rabaptin Fez1 PF06818.15 KFM63605.1 - 0.00024 21.6 19.0 0.17 12.4 0.1 2.1 2 0 0 2 2 2 2 Fez1 GIT_CC PF16559.5 KFM63605.1 - 0.0014 18.4 9.1 0.24 11.3 0.1 3.3 4 0 0 4 4 3 2 GIT coiled-coil Rho guanine nucleotide exchange factor Prefoldin_2 PF01920.20 KFM63605.1 - 0.0016 18.4 22.7 0.12 12.4 5.3 3.7 2 1 0 3 3 3 2 Prefoldin subunit Fib_alpha PF08702.10 KFM63605.1 - 0.003 17.7 12.3 1.2 9.4 11.5 2.1 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family TACC_C PF05010.14 KFM63605.1 - 0.0035 17.2 16.8 0.005 16.7 11.6 2.2 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cob_adeno_trans PF01923.18 KFM63605.1 - 0.0039 17.3 9.7 1.5 9.0 6.6 2.7 1 1 1 2 2 2 2 Cobalamin adenosyltransferase DUF1664 PF07889.12 KFM63605.1 - 0.004 17.2 13.0 1.4 9.0 0.1 3.3 1 1 1 3 3 3 1 Protein of unknown function (DUF1664) Phasin PF05597.11 KFM63605.1 - 0.0086 16.1 14.5 1.1 9.3 5.6 3.2 2 1 1 3 3 3 2 Poly(hydroxyalcanoate) granule associated protein (phasin) GAS PF13851.6 KFM63605.1 - 0.011 15.1 21.0 0.12 11.7 13.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 KFM63605.1 - 0.016 15.0 29.0 0.029 14.2 2.3 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Filament PF00038.21 KFM63605.1 - 0.022 14.4 22.1 3 7.3 0.3 3.0 2 1 1 3 3 3 0 Intermediate filament protein Uso1_p115_C PF04871.13 KFM63605.1 - 0.032 14.6 24.5 0.84 10.0 0.3 3.3 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DASH_Hsk3 PF08227.11 KFM63605.1 - 0.033 14.5 6.8 3.9 7.9 0.1 3.5 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DivIC PF04977.15 KFM63605.1 - 0.042 13.6 19.4 0.27 11.0 4.8 3.7 2 1 2 4 4 4 0 Septum formation initiator HMMR_N PF15905.5 KFM63605.1 - 0.052 13.0 18.8 0.61 9.5 12.6 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF724 PF05266.14 KFM63605.1 - 0.054 13.3 19.1 1.5 8.6 13.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4446 PF14584.6 KFM63605.1 - 0.061 13.3 11.3 2.9 7.9 4.3 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF4446) DUF16 PF01519.16 KFM63605.1 - 0.07 13.6 18.2 0.096 13.2 0.2 3.1 1 1 1 2 2 1 0 Protein of unknown function DUF16 FlxA PF14282.6 KFM63605.1 - 0.077 13.0 19.5 0.15 12.1 3.5 3.6 2 2 1 3 3 3 0 FlxA-like protein Macoilin PF09726.9 KFM63605.1 - 0.078 11.5 17.9 0.25 9.9 0.3 2.0 2 0 0 2 2 2 0 Macoilin family DUF3510 PF12022.8 KFM63605.1 - 0.078 13.4 13.2 0.042 14.2 8.1 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF3510) BST2 PF16716.5 KFM63605.1 - 0.089 13.4 1.4 0.089 13.4 1.4 3.4 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 CASP_C PF08172.12 KFM63605.1 - 0.091 12.1 17.6 0.057 12.8 5.6 2.9 1 1 2 3 3 3 0 CASP C terminal SlyX PF04102.12 KFM63605.1 - 0.091 13.4 19.9 0.28 11.8 1.5 3.4 2 1 1 3 3 3 0 SlyX DUF4407 PF14362.6 KFM63605.1 - 0.094 12.0 14.5 0.68 9.2 11.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) IFP_35_N PF07334.13 KFM63605.1 - 0.12 12.5 14.0 0.064 13.3 1.7 3.2 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HALZ PF02183.18 KFM63605.1 - 0.14 12.4 16.3 0.61 10.4 5.5 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper TerB_N PF13208.6 KFM63605.1 - 0.15 11.8 2.6 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 TerB N-terminal domain CCDC84 PF14968.6 KFM63605.1 - 0.16 11.6 4.4 0.21 11.2 4.4 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 DLP_helical PF18709.1 KFM63605.1 - 0.16 11.1 16.1 5.8 6.0 3.8 3.1 1 1 1 3 3 3 0 Dynamin-like helical domain Mto2_bdg PF12808.7 KFM63605.1 - 0.17 12.2 9.1 0.16 12.3 2.6 2.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cep57_CLD_2 PF14197.6 KFM63605.1 - 0.21 11.7 18.8 1.8 8.7 1.0 3.6 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 Seryl_tRNA_N PF02403.22 KFM63605.1 - 0.28 11.4 24.7 1.1 9.5 1.5 3.8 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Viral_P18 PF04521.13 KFM63605.1 - 0.3 10.9 8.2 3.8 7.3 0.1 2.7 2 1 0 3 3 2 0 ssRNA positive strand viral 18kD cysteine rich protein Ax_dynein_light PF10211.9 KFM63605.1 - 0.37 10.7 24.8 0.64 9.9 5.8 3.1 2 1 1 3 3 3 0 Axonemal dynein light chain FliJ PF02050.16 KFM63605.1 - 0.45 10.7 17.5 0.11 12.7 3.3 3.2 2 1 1 3 3 3 0 Flagellar FliJ protein DUF3584 PF12128.8 KFM63605.1 - 0.45 8.0 19.7 1.3 6.5 19.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.8 KFM63605.1 - 0.49 10.5 23.7 2.7 8.1 5.8 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding KxDL PF10241.9 KFM63605.1 - 0.51 10.7 8.3 1.5 9.2 0.7 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein CENP-F_leu_zip PF10473.9 KFM63605.1 - 0.58 10.2 28.9 1.2 9.2 1.1 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 KFM63605.1 - 0.61 10.7 18.4 9.4 6.9 0.2 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Lectin_N PF03954.14 KFM63605.1 - 0.65 9.7 11.5 22 4.8 0.3 3.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain WXG100 PF06013.12 KFM63605.1 - 0.66 10.2 7.9 3.8 7.8 0.7 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Cep57_MT_bd PF06657.13 KFM63605.1 - 0.71 10.4 18.8 0.76 10.3 0.5 3.9 4 1 0 4 4 3 0 Centrosome microtubule-binding domain of Cep57 TruB_C_2 PF16198.5 KFM63605.1 - 0.71 10.1 5.6 1.5 9.0 0.1 2.9 2 2 1 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain Rootletin PF15035.6 KFM63605.1 - 1 9.3 21.1 9.3 6.2 0.1 3.1 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF4140 PF13600.6 KFM63605.1 - 1.2 9.6 23.1 2.4 8.7 0.9 3.6 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF5320 PF17253.2 KFM63605.1 - 1.2 10.2 11.0 21 6.3 0.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5320) DUF4618 PF15397.6 KFM63605.1 - 1.3 8.4 21.7 5.4 6.3 1.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) SOGA PF11365.8 KFM63605.1 - 1.9 9.7 19.3 8.7 7.5 8.1 3.2 1 1 1 3 3 3 0 Protein SOGA DUF2802 PF10975.8 KFM63605.1 - 2 8.6 16.3 2.1 8.5 1.4 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF2802) Cnn_1N PF07989.11 KFM63605.1 - 2.1 8.6 23.8 4.8 7.4 1.1 3.6 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 Sec20 PF03908.13 KFM63605.1 - 2.3 8.2 8.4 2.9 7.9 0.1 3.1 3 0 0 3 3 3 0 Sec20 TMF_DNA_bd PF12329.8 KFM63605.1 - 2.7 8.0 27.5 2.6 8.1 1.7 4.0 2 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 KFM63605.1 - 3 6.6 27.9 3 6.6 13.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KFM63605.1 - 3 7.3 12.5 7.3 6.1 12.6 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit PRKG1_interact PF15898.5 KFM63605.1 - 3.1 8.8 24.0 1.3 10.0 15.2 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain FlaC_arch PF05377.11 KFM63605.1 - 3.1 8.2 19.0 2.7 8.5 1.7 3.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DinI PF06183.13 KFM63605.1 - 3.2 8.2 5.8 0.64 10.4 1.6 2.0 2 0 0 2 2 1 0 DinI-like family UPF0449 PF15136.6 KFM63605.1 - 3.6 8.1 15.1 16 6.0 4.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Spc24 PF08286.11 KFM63605.1 - 3.7 7.8 22.7 1.5 9.1 4.3 3.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 CorA PF01544.18 KFM63605.1 - 3.8 6.7 13.3 0.8 9.0 0.6 2.8 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein GrpE PF01025.19 KFM63605.1 - 4.2 7.0 23.2 11 5.7 0.2 3.2 2 1 1 3 3 3 0 GrpE HAUS-augmin3 PF14932.6 KFM63605.1 - 5.4 6.5 22.9 3.9 7.0 9.2 3.2 1 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Fungal_TACC PF12709.7 KFM63605.1 - 5.5 7.5 20.3 1.4 9.4 4.2 3.8 2 2 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Allexi_40kDa PF05549.11 KFM63605.1 - 5.5 6.4 11.7 4.9 6.6 2.5 2.5 1 1 2 3 3 3 0 Allexivirus 40kDa protein Alpha-2-MRAP_C PF06401.11 KFM63605.1 - 6.1 6.8 14.9 2.8 7.8 11.1 2.1 2 1 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain FapA PF03961.13 KFM63605.1 - 6.2 5.3 17.9 4.5 5.8 12.4 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A AATF-Che1 PF13339.6 KFM63605.1 - 6.7 7.4 16.0 5.4e+02 1.2 16.0 2.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor TMPIT PF07851.13 KFM63605.1 - 6.8 5.8 16.7 6.9 5.8 0.1 2.8 2 1 1 3 3 3 0 TMPIT-like protein Swi5 PF07061.11 KFM63605.1 - 7.1 6.8 19.8 6.2 7.0 3.6 3.9 2 2 1 3 3 3 0 Swi5 DUF1640 PF07798.11 KFM63605.1 - 8.2 6.4 23.1 9.3 6.3 15.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) CDO_I PF05995.12 KFM63606.1 - 3e-49 166.6 0.0 3.7e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KFM63606.1 - 0.016 14.7 0.1 0.52 9.7 0.0 2.2 1 1 0 2 2 2 0 PCO_ADO Cupin_2 PF07883.11 KFM63606.1 - 0.14 11.8 0.0 0.41 10.4 0.0 1.7 1 1 0 1 1 1 0 Cupin domain PP2C_C PF07830.13 KFM63608.1 - 0.099 13.1 0.4 0.17 12.4 0.4 1.5 1 1 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain EGF_2 PF07974.13 KFM63610.1 - 3.9e-05 23.9 9.3 3.9e-05 23.9 9.3 2.5 3 0 0 3 3 3 1 EGF-like domain ADAM_CR_2 PF17771.1 KFM63610.1 - 0.0092 16.5 0.2 0.0092 16.5 0.2 2.3 2 0 0 2 2 2 1 ADAM cysteine-rich domain Disintegrin PF00200.23 KFM63611.1 - 4.6e-08 33.7 0.6 4.6e-08 33.7 0.6 2.1 2 0 0 2 2 2 1 Disintegrin ADAM_CR PF08516.12 KFM63611.1 - 1.8e-07 31.5 1.5 1.8e-07 31.5 1.5 1.6 2 0 0 2 2 2 1 ADAM cysteine-rich Reprolysin PF01421.19 KFM63612.1 - 2.8e-52 177.5 0.2 3.3e-52 177.3 0.2 1.0 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KFM63612.1 - 1.9e-14 54.2 0.9 2.6e-14 53.8 0.9 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFM63612.1 - 5.7e-09 36.5 0.3 8.1e-09 36.0 0.3 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFM63612.1 - 3.7e-06 27.0 0.1 4.8e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFM63612.1 - 1.9e-05 24.4 2.1 3.7e-05 23.5 2.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 KFM63612.1 - 0.014 15.1 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.11 KFM63612.1 - 0.19 11.7 1.0 0.75 9.7 0.1 2.1 1 1 0 2 2 2 0 Peptidase family M54 DDE_3 PF13358.6 KFM63614.1 - 8e-14 51.6 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63614.1 - 7.7e-08 32.5 1.6 9e-08 32.3 0.5 1.8 2 0 0 2 2 2 1 Transposase CDRN PF05174.12 KFM63614.1 - 0.1 12.3 2.3 5.8 6.7 1.3 2.5 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus Asp_protease_2 PF13650.6 KFM63616.1 - 0.00091 19.8 0.0 0.0016 19.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KFM63616.1 - 0.0022 17.8 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 KFM63616.1 - 0.0062 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 KFM63616.1 - 0.0076 16.8 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 KFM63616.1 - 0.047 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) HTH_Tnp_Tc3_2 PF01498.18 KFM63617.1 - 2.4e-16 59.7 3.0 6e-16 58.5 3.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63617.1 - 0.00062 19.5 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63618.1 - 1.9e-19 69.7 3.6 5.2e-19 68.3 2.1 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63618.1 - 4.1e-16 59.1 0.0 2e-15 56.8 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM63618.1 - 3.2e-07 30.3 1.1 0.00013 21.9 0.0 2.7 3 0 0 3 3 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM63618.1 - 3.3e-07 30.8 2.0 3.3e-07 30.8 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63618.1 - 8.1e-07 29.1 2.3 7.1e-05 22.9 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63618.1 - 1.6e-06 27.7 3.5 2.3e-05 24.0 0.0 3.0 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM63618.1 - 2.4e-06 27.5 0.7 3.7e-05 23.7 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM63618.1 - 9.7e-05 22.2 0.6 0.0016 18.3 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM63618.1 - 0.001 19.0 0.4 0.015 15.2 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM63618.1 - 0.019 14.6 0.1 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM63618.1 - 0.042 13.9 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM63618.1 - 0.08 13.1 0.1 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM63618.1 - 0.15 11.6 0.2 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM63618.1 - 0.15 12.2 0.0 28 4.9 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM63618.1 - 0.25 11.2 3.9 1.4 8.8 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM63618.1 - 0.99 8.9 3.6 6.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 SCP2 PF02036.17 KFM63619.1 - 9.7e-36 122.3 3.3 6.3e-22 78.0 0.1 3.1 3 0 0 3 3 3 3 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KFM63619.1 - 8.7e-11 42.2 0.5 3.7e-05 24.0 0.0 2.8 3 0 0 3 3 3 2 Alkyl sulfatase C-terminal adh_short PF00106.25 KFM63620.1 - 4.3e-39 134.0 0.4 9.2e-39 132.9 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM63620.1 - 4.6e-32 111.4 0.0 9.3e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KFM63620.1 - 5.2e-31 106.8 0.0 1.2e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SCP2 PF02036.17 KFM63620.1 - 1.2e-30 106.0 1.1 4.3e-22 78.5 0.3 2.5 2 0 0 2 2 2 2 SCP-2 sterol transfer family KR PF08659.10 KFM63620.1 - 1.5e-15 57.5 0.2 2.8e-15 56.7 0.2 1.3 1 0 0 1 1 1 1 KR domain MaoC_dehydrat_N PF13452.6 KFM63620.1 - 2.6e-08 34.1 0.0 2.7e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Alkyl_sulf_C PF14864.6 KFM63620.1 - 1.8e-05 25.0 0.1 0.015 15.6 0.0 2.5 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal Invasin_D3 PF09134.10 KFM63620.1 - 0.061 13.6 0.1 9 6.7 0.0 2.5 2 0 0 2 2 2 0 Invasin, domain 3 E1_DerP2_DerF2 PF02221.15 KFM63621.1 - 1.4e-19 70.9 0.3 1.6e-19 70.7 0.3 1.0 1 0 0 1 1 1 1 ML domain Wzt_C PF14524.6 KFM63621.1 - 0.041 13.9 0.1 0.065 13.3 0.1 1.3 1 0 0 1 1 1 0 Wzt C-terminal domain E1_DerP2_DerF2 PF02221.15 KFM63622.1 - 5.9e-24 85.0 0.7 6.8e-24 84.8 0.7 1.0 1 0 0 1 1 1 1 ML domain NodZ PF05830.11 KFM63622.1 - 0.17 10.6 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) E1_DerP2_DerF2 PF02221.15 KFM63623.1 - 4.4e-15 56.3 0.7 5.6e-15 56.0 0.7 1.1 1 0 0 1 1 1 1 ML domain DUF928 PF06051.12 KFM63623.1 - 0.0047 16.8 0.1 0.014 15.2 0.0 1.6 1 1 1 2 2 2 1 Domain of Unknown Function (DUF928) Cdc6_C PF09079.11 KFM63623.1 - 0.65 10.0 3.4 11 6.1 0.2 2.6 2 1 1 3 3 3 0 CDC6, C terminal winged helix domain E1_DerP2_DerF2 PF02221.15 KFM63624.1 - 1.1e-20 74.4 0.2 1.2e-20 74.3 0.2 1.0 1 0 0 1 1 1 1 ML domain DUF928 PF06051.12 KFM63624.1 - 0.0048 16.8 0.0 0.033 14.0 0.0 1.9 1 1 1 2 2 2 1 Domain of Unknown Function (DUF928) Wzt_C PF14524.6 KFM63624.1 - 0.027 14.5 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Wzt C-terminal domain PH PF00169.29 KFM63625.1 - 2.8e-08 34.2 0.3 7e-08 32.9 0.3 1.7 1 0 0 1 1 1 1 PH domain RA PF00788.23 KFM63625.1 - 9.7e-06 26.1 0.1 2.9e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RHH_5 PF07878.11 KFM63625.1 - 0.0032 17.3 0.1 0.0059 16.5 0.1 1.4 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 PH_11 PF15413.6 KFM63625.1 - 0.18 12.2 0.3 0.5 10.8 0.3 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain EGF_3 PF12947.7 KFM63627.1 - 1.3e-05 25.3 8.7 1.3e-05 25.3 8.7 14.1 13 4 2 15 15 15 4 EGF domain EGF PF00008.27 KFM63627.1 - 0.00023 21.4 32.6 0.0011 19.2 7.9 15.1 12 5 1 13 13 13 5 EGF-like domain Plasmod_Pvs28 PF06247.11 KFM63627.1 - 0.0068 16.7 4.2 0.0068 16.7 4.2 13.6 11 3 2 13 13 13 2 Pvs28 EGF domain hEGF PF12661.7 KFM63627.1 - 0.018 15.7 14.3 0.027 15.1 3.0 16.4 15 3 0 15 15 15 0 Human growth factor-like EGF Antimicrobial25 PF16839.5 KFM63627.1 - 0.021 14.9 1.9 0.021 14.9 1.9 11.6 4 3 5 11 11 11 0 Nematode antimicrobial peptide DUF4817 PF16087.5 KFM63628.1 - 1.3e-10 40.9 0.0 1.4e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_48 PF17906.1 KFM63628.1 - 0.1 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Thioredoxin PF00085.20 KFM63629.1 - 4.1e-23 81.3 0.0 4.7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM63629.1 - 4.1e-05 24.0 0.0 8.8e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM63629.1 - 0.009 16.3 0.0 0.043 14.2 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KFM63629.1 - 0.085 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family OST3_OST6 PF04756.13 KFM63629.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Fringe PF02434.16 KFM63630.1 - 1.9e-55 188.0 0.1 3.3e-47 161.0 0.1 2.1 2 0 0 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 KFM63630.1 - 4.8e-08 33.1 0.0 0.14 12.0 0.0 3.3 2 1 1 3 3 3 3 Galactosyltransferase DUF604 PF04646.12 KFM63630.1 - 0.00073 19.0 0.1 0.017 14.5 0.0 3.1 3 1 1 4 4 4 1 Protein of unknown function, DUF604 PAC3 PF10178.9 KFM63630.1 - 0.1 12.7 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 zf-H2C2_2 PF13465.6 KFM63631.1 - 1.8e-45 151.4 67.9 2e-06 27.9 1.8 10.3 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63631.1 - 7.6e-33 111.1 88.4 1.1e-05 25.6 1.5 10.1 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63631.1 - 4.3e-31 104.9 79.2 0.0013 19.4 0.4 10.1 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFM63631.1 - 1.9e-24 85.2 65.8 0.0014 19.0 0.8 9.8 9 1 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM63631.1 - 1.7e-16 59.8 66.0 0.0038 17.2 2.0 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM63631.1 - 2.3e-16 59.6 68.2 0.0014 18.9 0.2 9.8 10 0 0 10 10 9 8 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM63631.1 - 3.3e-05 24.1 4.4 0.17 12.2 0.0 5.1 2 2 1 4 4 4 2 BolA-like protein zf-C2HC_2 PF13913.6 KFM63631.1 - 0.00011 21.9 34.0 0.036 14.0 0.0 8.2 7 1 1 8 8 8 4 zinc-finger of a C2HC-type GAGA PF09237.11 KFM63631.1 - 0.0047 16.7 27.8 0.22 11.4 0.6 6.5 2 2 4 7 7 7 3 GAGA factor zf-C2H2_2 PF12756.7 KFM63631.1 - 0.028 14.7 55.9 0.88 9.9 9.4 7.9 1 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) VATC PF18716.1 KFM63631.1 - 0.049 13.5 1.4 0.049 13.5 1.4 9.4 8 3 3 11 11 11 0 Vms1-associating treble clef domain ADK_lid PF05191.14 KFM63631.1 - 0.095 12.7 32.9 0.19 11.8 1.4 5.4 4 2 1 5 5 4 0 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM63631.1 - 0.099 12.8 35.8 1.5 9.0 0.1 8.9 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF5385 PF17359.2 KFM63632.1 - 0.028 14.0 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) TMEM154 PF15102.6 KFM63632.1 - 0.048 13.6 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family TUDOR PF00567.24 KFM63633.1 - 4.5e-24 84.8 0.0 1.2e-23 83.4 0.0 1.8 2 0 0 2 2 2 1 Tudor domain KH_1 PF00013.29 KFM63633.1 - 2e-11 43.5 0.0 5.5e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KFM63633.1 - 0.0077 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 KH domain T-box PF00907.22 KFM63633.1 - 0.052 13.8 0.1 0.13 12.5 0.1 1.6 1 1 0 1 1 1 0 T-box HTH_Tnp_Tc3_2 PF01498.18 KFM63634.1 - 6.6e-15 55.1 5.4 1.4e-14 54.1 5.4 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 KFM63634.1 - 0.0049 16.9 0.2 0.0049 16.9 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KFM63634.1 - 0.028 14.2 0.0 0.028 14.2 0.0 2.3 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM63634.1 - 0.042 13.7 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Tc3 transposase OrsD PF12013.8 KFM63634.1 - 0.096 13.1 0.3 0.15 12.5 0.3 1.2 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D HTH_32 PF13565.6 KFM63634.1 - 0.78 10.4 14.0 5.5 7.7 2.0 2.5 1 1 1 2 2 2 0 Homeodomain-like domain 7tm_1 PF00001.21 KFM63635.1 - 0.00028 20.3 3.9 0.00034 20.0 2.6 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Reg_prop PF07494.11 KFM63636.1 - 0.013 15.6 0.0 0.77 10.2 0.0 2.7 2 0 0 2 2 2 0 Two component regulator propeller PH_10 PF15411.6 KFM63638.1 - 0.012 15.9 0.2 0.014 15.6 0.2 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain NUDIX_5 PF16705.5 KFM63638.1 - 0.087 12.6 0.1 0.11 12.3 0.1 1.3 1 1 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT RhoGEF PF00621.20 KFM63639.1 - 2.8e-37 128.7 0.1 4.6e-37 128.0 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain GPS2_interact PF15784.5 KFM63639.1 - 0.013 16.0 1.4 0.023 15.1 1.4 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4817 PF16087.5 KFM63640.1 - 5.3e-09 35.7 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 KFM63640.1 - 7.7e-05 23.2 0.0 0.00038 21.0 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63640.1 - 0.00096 18.9 0.2 1.3 9.0 0.0 3.3 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 KFM63640.1 - 0.0067 16.5 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain AAA_33 PF13671.6 KFM63640.1 - 0.076 13.2 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain CENP-B_N PF04218.13 KFM63640.1 - 0.13 11.9 0.1 1.1 9.0 0.0 2.6 3 1 1 4 4 4 0 CENP-B N-terminal DNA-binding domain Peptidase_S41 PF03572.18 KFM63641.1 - 0.0033 17.0 0.2 0.007 16.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase family S41 DUF1340 PF07067.11 KFM63641.1 - 0.093 12.1 5.2 0.65 9.3 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1340) HTH_Tnp_Tc3_2 PF01498.18 KFM63642.1 - 3.2e-14 52.9 1.7 6.7e-14 51.9 1.7 1.6 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM63642.1 - 8.5e-07 29.0 4.5 2.7e-05 24.2 0.1 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain PAX PF00292.18 KFM63642.1 - 2.7e-05 24.1 0.1 4.6e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFM63642.1 - 6.6e-05 22.6 6.9 0.0038 17.0 0.1 3.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63642.1 - 0.001 19.7 6.3 0.001 19.7 6.3 2.5 2 1 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM63642.1 - 0.0011 18.8 1.4 0.0076 16.1 0.1 2.3 2 0 0 2 2 2 1 MarR family HTH_29 PF13551.6 KFM63642.1 - 0.0021 18.0 1.2 0.048 13.7 0.2 2.5 2 0 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.19 KFM63642.1 - 0.0025 17.7 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Tnp_IS630 PF01710.16 KFM63642.1 - 0.01 15.9 0.1 0.35 10.9 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_3 PF01381.22 KFM63642.1 - 0.012 15.6 0.6 0.4 10.8 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix DDE_3 PF13358.6 KFM63642.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.6 KFM63642.1 - 0.017 14.5 1.0 0.83 9.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_37 PF13744.6 KFM63642.1 - 0.025 14.6 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 KFM63642.1 - 0.025 14.3 0.1 0.025 14.3 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 KFM63642.1 - 0.039 14.0 3.5 0.61 10.2 1.7 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_22 PF13309.6 KFM63642.1 - 0.068 13.2 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 HTH domain DUF5447 PF17525.2 KFM63642.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5447) HTH_Crp_2 PF13545.6 KFM63642.1 - 0.13 12.3 2.2 0.4 10.7 0.1 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM63642.1 - 0.15 11.7 0.7 6.5 6.4 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 KFM63642.1 - 0.28 11.7 0.4 6.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM63643.1 - 5.3e-16 58.6 2.2 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63643.1 - 1.1e-13 51.2 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63643.1 - 1.5e-07 31.0 1.1 5.6e-07 29.2 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63643.1 - 0.0018 18.0 0.6 0.005 16.6 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63643.1 - 0.0087 16.2 0.5 0.027 14.6 0.5 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM63643.1 - 2.5 8.8 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain 7tm_1 PF00001.21 KFM63644.1 - 0.0038 16.6 1.0 0.0043 16.4 1.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM63644.1 - 0.066 12.6 0.1 0.07 12.5 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Chlor_dismutase PF06778.12 KFM63645.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Chlorite dismutase EloA-BP1 PF15870.5 KFM63646.1 - 8.3e-55 185.5 0.3 8.3e-55 185.5 0.3 4.6 2 1 2 4 4 4 1 ElonginA binding-protein 1 RNase_T PF00929.24 KFM63646.1 - 6.5e-07 30.0 0.8 3.2e-06 27.8 0.1 2.4 2 0 0 2 2 2 1 Exonuclease Vps54_N PF10475.9 KFM63647.1 - 0.41 9.9 1.9 0.59 9.4 1.9 1.1 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Ion_trans_2 PF07885.16 KFM63648.1 - 2.1e-18 66.0 0.9 3e-18 65.6 0.9 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFM63648.1 - 5.1e-06 25.9 0.0 6.4e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein DUF1129 PF06570.11 KFM63648.1 - 0.02 14.4 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) HAUS-augmin3 PF14932.6 KFM63648.1 - 0.096 12.3 1.2 0.11 12.1 0.6 1.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 G2F PF07474.12 KFM63649.1 - 3.7e-66 222.4 0.0 5.3e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 G2F domain EGF_3 PF12947.7 KFM63649.1 - 2.2e-62 206.9 190.9 3.1e-10 40.1 5.6 13.7 13 0 0 13 13 13 12 EGF domain Ldl_recept_b PF00058.17 KFM63649.1 - 3.2e-39 133.1 4.9 1.8e-10 41.1 0.1 5.8 5 1 0 5 5 5 5 Low-density lipoprotein receptor repeat class B EGF PF00008.27 KFM63649.1 - 4e-25 87.7 172.3 0.0016 18.7 6.7 13.7 13 0 0 13 13 13 11 EGF-like domain cEGF PF12662.7 KFM63649.1 - 1.5e-22 79.2 136.2 0.00028 20.8 2.1 13.5 13 0 0 13 13 13 11 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 KFM63649.1 - 5.5e-18 64.7 158.2 0.00065 19.7 7.0 12.5 12 0 0 12 12 12 9 MSP1 EGF domain 1 EGF_CA PF07645.15 KFM63649.1 - 1.4e-13 50.8 32.7 1.2e-10 41.4 5.6 13.7 11 2 2 13 13 13 5 Calcium-binding EGF domain hEGF PF12661.7 KFM63649.1 - 1.8e-13 50.5 132.8 0.0014 19.2 1.9 15.7 14 0 0 14 14 14 10 Human growth factor-like EGF NIDO PF06119.14 KFM63649.1 - 0.00022 22.1 0.0 0.00052 20.9 0.0 1.7 1 0 0 1 1 1 1 Nidogen-like FXa_inhibition PF14670.6 KFM63649.1 - 0.0014 18.8 181.0 0.0018 18.5 7.8 13.6 9 2 4 13 13 13 5 Coagulation Factor Xa inhibitory site SGL PF08450.12 KFM63649.1 - 0.0035 17.0 0.4 1.7 8.1 0.1 3.6 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Metallophos PF00149.28 KFM63650.1 - 2.6e-35 122.8 0.2 4.5e-35 122.0 0.1 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KFM63650.1 - 6.1e-31 106.6 0.2 1.2e-30 105.7 0.2 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region DUF489 PF04356.12 KFM63650.1 - 0.08 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) TPR_1 PF00515.28 KFM63651.1 - 1e-12 47.3 4.2 2.1e-09 36.8 0.2 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM63651.1 - 8.5e-11 41.1 4.0 2e-06 27.4 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM63651.1 - 6.2e-07 29.0 1.3 2.3e-05 24.0 0.5 2.3 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 KFM63651.1 - 0.00011 22.8 0.0 0.00017 22.1 0.0 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM63651.1 - 0.00045 20.8 0.0 0.0015 19.2 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM63651.1 - 0.00062 19.8 2.0 0.0081 16.3 0.0 2.6 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM63651.1 - 0.0012 19.1 1.2 0.013 15.8 0.4 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 KFM63651.1 - 0.0015 18.5 2.4 0.013 15.5 1.2 2.4 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 KFM63651.1 - 0.0037 17.4 0.0 0.0049 17.0 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM63651.1 - 0.0043 17.0 0.4 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM63651.1 - 0.021 15.1 0.6 0.12 12.7 0.6 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM63651.1 - 0.026 15.2 0.8 0.46 11.2 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat HEPN PF05168.14 KFM63651.1 - 0.057 13.5 2.7 0.087 13.0 2.7 1.5 1 1 0 1 1 1 0 HEPN domain TPR_19 PF14559.6 KFM63651.1 - 0.065 13.8 0.1 0.15 12.6 0.0 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat RapH_N PF18801.1 KFM63651.1 - 0.22 11.6 3.2 3.2 7.9 1.9 2.2 1 1 1 2 2 2 0 response regulator aspartate phosphatase H, N terminal vATP-synt_E PF01991.18 KFM63651.1 - 0.34 10.3 4.2 1.2 8.5 4.6 1.6 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit HTH_Tnp_Tc3_2 PF01498.18 KFM63652.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63652.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63652.1 - 1.7e-07 30.8 1.2 6.7e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63652.1 - 0.0025 17.6 0.6 0.0072 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain SapB_1 PF05184.15 KFM63653.1 - 0.00022 21.2 1.5 0.0004 20.3 0.3 2.2 2 0 0 2 2 2 1 Saposin-like type B, region 1 Metallophos PF00149.28 KFM63654.1 - 5.3e-09 36.9 0.0 6.2e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1722 PF08349.11 KFM63654.1 - 0.17 12.2 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) LRR_8 PF13855.6 KFM63656.1 - 4e-26 90.5 8.5 2.9e-09 36.6 0.0 4.4 4 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFM63656.1 - 3.3e-14 52.8 11.5 3.2e-05 24.2 0.0 4.9 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM63656.1 - 2.2e-09 36.6 6.8 0.26 12.0 0.0 7.1 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_5 PF13306.6 KFM63656.1 - 1.3e-07 31.6 0.0 1.8e-05 24.7 0.0 2.8 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFM63656.1 - 2.3e-07 30.3 11.0 0.73 10.0 0.1 6.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 KFM63656.1 - 0.01 15.4 0.3 0.044 13.3 0.2 1.9 1 1 1 2 2 2 2 Leucine-rich repeat HTH_Tnp_Tc3_2 PF01498.18 KFM63657.1 - 1.6e-08 34.7 5.6 3.7e-08 33.5 5.6 1.7 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 KFM63657.1 - 0.00018 21.2 0.0 0.0008 19.1 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM63657.1 - 0.066 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Tc3 transposase Pox_A9 PF04835.12 KFM63658.1 - 0.051 13.7 0.7 0.072 13.2 0.7 1.2 1 0 0 1 1 1 0 A9 protein conserved region XK-related PF09815.9 KFM63659.1 - 2.9e-77 260.1 22.8 3.2e-77 259.9 22.8 1.0 1 0 0 1 1 1 1 XK-related protein XK-related PF09815.9 KFM63660.1 - 3.8e-20 72.3 1.8 4.3e-20 72.1 1.8 1.0 1 0 0 1 1 1 1 XK-related protein Sulfotransfer_3 PF13469.6 KFM63661.1 - 2.3e-21 77.2 0.0 4.3e-21 76.3 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM63661.1 - 0.043 13.3 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain AAA_13 PF13166.6 KFM63663.1 - 0.0071 15.0 12.6 0.008 14.9 12.6 1.0 1 0 0 1 1 1 1 AAA domain FliJ PF02050.16 KFM63663.1 - 0.013 15.7 19.4 0.046 13.9 7.8 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein NICE-3 PF07406.11 KFM63663.1 - 0.029 14.4 4.3 0.035 14.1 4.3 1.1 1 0 0 1 1 1 0 NICE-3 protein SlyX PF04102.12 KFM63663.1 - 0.033 14.8 13.1 0.37 11.4 2.0 2.4 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 KFM63663.1 - 0.09 12.6 18.5 0.5 10.2 2.4 2.7 2 1 0 2 2 2 0 Septum formation initiator Herpes_UL6 PF01763.16 KFM63663.1 - 0.19 10.2 13.2 1.2 7.6 1.2 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like TMF_DNA_bd PF12329.8 KFM63663.1 - 0.37 10.8 22.8 0.8 9.7 7.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1281 PF06924.11 KFM63663.1 - 0.5 9.9 3.0 0.64 9.5 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1281) Fib_alpha PF08702.10 KFM63663.1 - 0.78 9.9 14.3 1.2 9.3 14.1 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GPHR_N PF12537.8 KFM63663.1 - 0.85 9.7 6.1 0.44 10.7 0.7 2.4 2 1 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Plk4_PB2 PF18409.1 KFM63663.1 - 1.1 9.9 7.1 2.7 8.7 1.9 2.2 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 DUF641 PF04859.12 KFM63663.1 - 1.3 9.4 18.2 3.6 7.9 5.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KFM63663.1 - 1.4 7.7 23.3 0.5 9.2 8.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 KFM63663.1 - 1.8 9.1 25.1 1.2 9.7 9.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4446 PF14584.6 KFM63663.1 - 1.9 8.4 14.3 1.3 9.0 5.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) COG2 PF06148.11 KFM63663.1 - 2 8.5 12.3 0.7 10.0 3.1 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BRE1 PF08647.11 KFM63663.1 - 3 8.0 26.2 1.5 8.9 10.6 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Exonuc_VII_L PF02601.15 KFM63663.1 - 3.3 7.2 14.6 3.7 7.0 14.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 KFM63663.1 - 5.7 7.0 24.3 12 5.9 24.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MRP-L51 PF10244.9 KFM63664.1 - 3.1e-24 85.0 0.2 5.5e-24 84.2 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit Glyco_hydro_18 PF00704.28 KFM63666.1 - 4.7e-18 66.0 0.0 6.2e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 KFM63666.1 - 0.0059 16.1 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Amino_oxidase PF01593.24 KFM63667.1 - 6.7e-35 121.2 0.0 8.6e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lipase PF00151.19 KFM63668.1 - 6.9e-26 91.4 0.1 8.2e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 Lipase RT_RNaseH_2 PF17919.1 KFM63669.1 - 9e-32 109.1 0.0 1.9e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM63669.1 - 2e-29 102.0 0.0 5.2e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM63669.1 - 1.4e-25 90.1 0.1 2.4e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM63669.1 - 3e-22 79.0 0.0 7.5e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM63669.1 - 2.5e-19 69.1 0.3 5.4e-19 68.1 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KFM63669.1 - 3e-05 23.7 0.0 7.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KFM63669.1 - 3.2e-05 24.0 0.1 8.5e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 KFM63669.1 - 0.00051 20.6 0.0 0.0016 18.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM63669.1 - 0.0067 17.0 0.0 0.019 15.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 KFM63669.1 - 0.011 15.8 0.3 0.026 14.6 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF809 PF05663.11 KFM63669.1 - 0.43 10.7 8.2 1.4 9.1 8.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Topoisom_I_N PF02919.15 KFM63669.1 - 0.86 9.1 7.5 0.22 11.0 2.7 2.3 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF4661 PF15576.6 KFM63669.1 - 3.7 7.4 7.4 8.2 6.3 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) HTH_Tnp_Tc3_2 PF01498.18 KFM63670.1 - 4.6e-30 103.7 14.2 2.6e-15 56.4 6.5 2.4 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM63670.1 - 4.7e-16 58.9 0.3 5.5e-14 52.1 0.0 3.2 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_33 PF13592.6 KFM63670.1 - 0.00034 20.2 1.6 0.026 14.2 0.2 2.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KFM63670.1 - 0.0013 19.3 1.5 0.0013 19.3 1.5 4.5 4 1 0 4 4 4 2 Homeodomain-like domain HTH_23 PF13384.6 KFM63670.1 - 0.0034 17.2 0.6 0.19 11.6 0.0 3.7 4 0 0 4 4 4 1 Homeodomain-like domain HTH_29 PF13551.6 KFM63670.1 - 0.059 13.4 0.4 0.059 13.4 0.4 2.7 4 0 0 4 4 4 0 Winged helix-turn helix HTH_28 PF13518.6 KFM63670.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain Lipase PF00151.19 KFM63671.1 - 1.8e-41 142.6 0.1 1.9e-41 142.5 0.1 1.1 1 0 0 1 1 1 1 Lipase Lipase PF00151.19 KFM63672.1 - 1.2e-75 255.0 0.1 8.6e-66 222.5 0.0 2.0 1 1 1 2 2 2 2 Lipase Abhydrolase_6 PF12697.7 KFM63672.1 - 0.00053 20.7 0.1 0.00066 20.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KFM63672.1 - 0.0076 15.8 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase PF00151.19 KFM63673.1 - 7.6e-81 272.0 1.5 1.3e-68 231.8 0.0 2.0 1 1 1 2 2 2 2 Lipase DUF1759 PF03564.15 KFM63674.1 - 2.7e-32 111.8 0.3 4e-32 111.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Peptidase_A17 PF05380.13 KFM63674.1 - 1.5e-18 67.3 0.0 2.5e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase RT_RNaseH_2 PF17919.1 KFM63674.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase BBIP10 PF14777.6 KFM63674.1 - 1.9 8.1 4.2 0.77 9.4 0.3 2.1 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 Lipase PF00151.19 KFM63675.1 - 3e-86 289.8 0.3 1.6e-66 224.9 0.0 2.0 2 0 0 2 2 2 2 Lipase Abhydrolase_6 PF12697.7 KFM63675.1 - 3.1e-05 24.7 0.1 4.4e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DCAF17 PF15802.5 KFM63677.1 - 4.8e-66 223.4 0.0 5.4e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 DDB1- and CUL4-associated factor 17 tRNA-synt_2 PF00152.20 KFM63678.1 - 6.9e-77 258.6 0.0 1e-76 258.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFM63678.1 - 7.5e-10 38.7 0.3 1.4e-09 37.8 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFM63678.1 - 8.4e-05 22.2 0.1 0.23 10.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 KFM63678.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DDE_1 PF03184.19 KFM63679.1 - 6e-06 26.0 0.1 6.4e-06 25.9 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1765 PF08578.10 KFM63680.1 - 0.017 15.5 0.5 0.024 15.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) HTH_Tnp_Tc3_2 PF01498.18 KFM63681.1 - 1.9e-06 28.1 1.0 2.3e-06 27.7 1.0 1.3 1 1 0 1 1 1 1 Transposase zf-H2C2_2 PF13465.6 KFM63683.1 - 2.7e-54 179.3 45.7 2.6e-08 33.9 0.5 7.3 7 1 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63683.1 - 3.3e-36 121.7 55.1 2e-06 28.0 0.3 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63683.1 - 3.9e-26 89.5 51.4 6.7e-05 23.4 0.4 7.2 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 KFM63683.1 - 4.2e-24 84.1 52.4 6.6e-05 23.2 0.5 7.6 7 1 0 7 7 7 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63683.1 - 3.6e-17 62.2 38.5 0.00029 21.0 0.2 8.3 7 2 0 7 7 7 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM63683.1 - 3.2e-12 46.1 41.7 0.2 11.7 0.5 7.8 7 1 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63683.1 - 7.8e-07 28.7 30.2 0.096 12.5 0.1 6.5 6 0 0 6 6 6 4 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM63683.1 - 8e-07 28.8 20.3 0.26 11.2 0.3 7.3 7 0 0 7 7 7 2 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM63683.1 - 4e-06 26.8 17.6 11 6.3 0.0 7.1 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Sec23_Sec24 PF04810.15 KFM63683.1 - 0.00027 20.9 23.5 4 7.6 0.1 6.9 5 1 2 7 7 7 1 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM63683.1 - 0.00048 20.0 23.0 0.084 12.9 2.0 4.5 3 1 0 3 3 3 2 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM63683.1 - 0.00058 19.4 27.6 0.052 13.2 0.3 6.2 2 2 4 6 6 6 1 MYST family zinc finger domain C1_1 PF00130.22 KFM63683.1 - 0.00085 19.2 35.3 0.67 9.9 8.3 5.8 1 1 5 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 KFM63683.1 - 0.0012 19.0 35.2 0.23 11.6 8.1 4.1 1 1 3 4 4 4 3 FYVE zinc finger TRAF6_Z2 PF18048.1 KFM63683.1 - 0.003 17.6 28.5 0.11 12.7 2.6 6.2 6 0 0 6 6 6 2 TNF receptor-associated factor 6 zinc finger 2 C5HCH PF17982.1 KFM63683.1 - 0.0058 16.8 32.4 4.2 7.6 2.1 7.0 3 1 3 7 7 7 1 NSD Cys-His rich domain BolA PF01722.18 KFM63683.1 - 0.019 15.2 9.9 0.61 10.4 0.3 4.0 1 1 2 4 4 4 0 BolA-like protein zf-DBF PF07535.12 KFM63683.1 - 0.031 14.4 33.9 8.4 6.6 0.1 7.2 7 0 0 7 7 7 0 DBF zinc finger zf-C2H2_9 PF16293.5 KFM63683.1 - 0.067 13.0 24.0 6.5 6.7 0.2 6.2 4 2 2 6 6 6 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM63683.1 - 0.11 13.2 25.5 1 10.2 1.6 3.9 1 1 2 4 4 4 0 zinc-ribbon family zf-CHCC PF10276.9 KFM63683.1 - 0.56 10.3 12.2 26 5.0 0.1 5.9 7 0 0 7 7 7 0 Zinc-finger domain zf_UBZ PF18439.1 KFM63683.1 - 0.6 9.8 32.5 11 5.7 0.1 7.2 6 1 1 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM63683.1 - 0.63 10.2 26.1 0.88 9.7 4.6 3.4 1 1 1 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF4764 PF15961.5 KFM63683.1 - 0.79 8.3 22.3 0.68 8.6 0.9 4.7 1 1 3 5 5 5 0 Domain of unknown function (DUF4764) zf-Dof PF02701.15 KFM63683.1 - 0.81 9.9 18.5 2.2 8.5 1.9 4.8 1 1 4 5 5 5 0 Dof domain, zinc finger zf-HIT PF04438.16 KFM63683.1 - 0.94 9.4 32.7 5.1 7.1 0.5 7.0 7 0 0 7 7 7 0 HIT zinc finger SPARC_Ca_bdg PF10591.9 KFM63683.1 - 1.3 9.4 9.3 6.5 7.1 0.3 4.0 3 1 2 5 5 4 0 Secreted protein acidic and rich in cysteine Ca binding region zf-FCS PF06467.14 KFM63683.1 - 2.7 8.0 25.1 9.2 6.3 0.1 6.6 5 2 2 7 7 7 0 MYM-type Zinc finger with FCS sequence motif Zf_RING PF16744.5 KFM63683.1 - 4.3 7.5 32.7 8 6.7 2.8 6.7 1 1 4 5 5 4 0 KIAA1045 RING finger Rpr2 PF04032.16 KFM63683.1 - 9 6.7 27.7 0.82 10.0 2.1 4.9 1 1 4 5 5 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_2 PF13465.6 KFM63684.1 - 1.2e-117 379.6 102.7 5.8e-09 36.0 0.4 17.3 17 0 0 17 17 17 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63684.1 - 3.8e-81 263.3 111.3 1.7e-05 25.0 1.3 17.1 17 0 0 17 17 17 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63684.1 - 3.5e-47 155.0 110.2 0.0062 17.3 1.0 17.2 17 0 0 17 17 17 17 C2H2-type zinc finger zf-met PF12874.7 KFM63684.1 - 2.6e-42 142.0 117.1 0.0017 18.7 1.1 17.3 17 0 0 17 17 17 16 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM63684.1 - 8e-28 95.8 64.4 0.051 13.3 0.0 16.8 17 0 0 17 17 17 12 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM63684.1 - 6.8e-20 70.8 99.3 0.12 12.7 0.3 17.3 16 2 1 17 17 17 11 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM63684.1 - 9.9e-16 57.3 111.3 0.068 13.2 0.5 17.1 17 1 0 17 17 16 11 C2H2-type zinc finger ADK_lid PF05191.14 KFM63684.1 - 2.4e-11 43.4 53.9 0.045 13.8 1.4 9.5 4 1 8 12 12 12 9 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM63684.1 - 1.8e-07 31.2 17.8 0.13 12.5 0.3 7.7 1 1 8 9 9 9 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2HC_2 PF13913.6 KFM63684.1 - 6.4e-07 29.1 57.4 1.6 8.7 0.0 15.3 17 0 0 17 17 16 2 zinc-finger of a C2HC-type C1_1 PF00130.22 KFM63684.1 - 4.3e-06 26.5 69.6 1.7 8.6 1.2 12.5 5 3 7 13 13 13 5 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 KFM63684.1 - 0.00012 22.1 60.8 2.4 8.4 0.5 14.7 17 0 0 17 17 15 2 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.18 KFM63684.1 - 0.00022 21.4 23.7 3.3 8.1 0.2 8.0 1 1 9 10 10 10 2 BolA-like protein DUF2039 PF10217.9 KFM63684.1 - 0.00027 21.2 62.4 0.0045 17.3 8.6 7.1 2 2 6 8 8 8 4 Uncharacterized conserved protein (DUF2039) zf-Sec23_Sec24 PF04810.15 KFM63684.1 - 0.00037 20.5 62.0 0.55 10.3 1.0 13.8 9 5 6 15 15 15 2 Sec23/Sec24 zinc finger zinc_ribbon_15 PF17032.5 KFM63684.1 - 0.0032 18.2 60.9 0.81 10.5 1.7 8.3 2 1 8 10 10 10 4 zinc-ribbon family GAGA PF09237.11 KFM63684.1 - 0.0033 17.2 25.9 0.049 13.4 0.1 8.2 6 2 4 10 10 10 2 GAGA factor Complex1_49kDa PF00346.19 KFM63684.1 - 0.0087 15.2 0.5 7.4 5.6 0.0 3.2 1 1 2 4 4 4 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-C2H2_9 PF16293.5 KFM63684.1 - 0.015 15.1 63.2 2.2 8.2 0.1 15.4 2 1 15 17 17 17 0 C2H2 type zinc-finger (1 copy) YppF PF14178.6 KFM63684.1 - 0.26 11.2 4.7 1.5e+02 2.3 0.0 5.6 7 1 0 7 7 6 0 YppF-like protein HNH_5 PF14279.6 KFM63684.1 - 0.4 10.6 70.4 7.6 6.5 0.7 13.5 8 7 3 11 11 11 0 HNH endonuclease zf_UBZ PF18439.1 KFM63684.1 - 1 9.0 68.9 8 6.2 0.1 15.6 17 0 0 17 17 17 0 Ubiquitin-Binding Zinc Finger Ig_3 PF13927.6 KFM63686.1 - 1.3e-29 102.5 0.0 2.6e-11 44.0 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM63686.1 - 1.3e-28 98.9 0.0 6.2e-14 51.8 0.1 3.0 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM63686.1 - 3.5e-22 78.5 0.0 3.7e-09 36.8 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM63686.1 - 1.5e-19 70.0 0.0 1.1e-06 28.8 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM63686.1 - 3.7e-12 46.4 0.2 0.058 13.6 0.0 4.3 3 2 1 4 4 4 4 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM63686.1 - 1.7e-06 28.2 0.0 0.0017 18.6 0.0 3.5 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM63686.1 - 7.9e-06 26.2 0.0 0.001 19.4 0.0 3.1 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM63686.1 - 0.00013 21.5 0.0 0.75 9.4 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFM63686.1 - 0.00021 21.3 0.1 0.39 10.8 0.1 3.4 3 1 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM63686.1 - 0.0049 16.9 0.0 8.5 6.5 0.0 3.3 3 1 0 3 3 3 1 C17orf99 Ig domain C2-set_2 PF08205.12 KFM63686.1 - 0.013 15.6 0.0 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KFM63686.1 - 0.017 15.1 0.2 4.4 7.3 0.0 3.3 2 1 1 3 3 3 0 CD47 immunoglobulin-like domain Herpes_gE PF02480.16 KFM63686.1 - 0.036 12.8 0.2 0.15 10.8 0.0 1.8 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR1 PF02440.15 KFM63686.1 - 0.097 12.5 0.2 14 5.6 0.0 3.3 3 2 0 3 3 3 0 Adenovirus E3 region protein CR1 RE_NgoFVII PF09565.10 KFM63686.1 - 0.13 11.6 0.2 1.8 7.8 0.3 2.1 1 1 1 2 2 2 0 NgoFVII restriction endonuclease Receptor_2B4 PF11465.8 KFM63686.1 - 0.15 12.2 0.0 0.46 10.7 0.0 1.9 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 UMPH-1 PF05822.12 KFM63688.1 - 5.7e-42 143.9 0.1 6.1e-42 143.8 0.1 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF3473 PF11959.8 KFM63688.1 - 0.046 13.7 0.1 0.08 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) SSFA2_C PF14723.6 KFM63688.1 - 0.15 11.9 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM63690.1 - 2.3e-15 56.6 0.9 4.9e-15 55.5 0.9 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63690.1 - 1.7e-14 53.8 0.0 2.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM63690.1 - 6.5e-05 23.5 10.5 8.5e-05 23.1 2.8 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_3 PF01381.22 KFM63690.1 - 0.0025 17.8 0.7 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM63690.1 - 0.031 14.2 0.9 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM63690.1 - 0.037 13.6 0.7 0.96 9.1 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KFM63690.1 - 0.043 13.7 1.1 0.096 12.6 0.0 2.1 2 1 0 2 2 2 0 MarR family PAX PF00292.18 KFM63690.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain HTH_23 PF13384.6 KFM63690.1 - 0.12 12.2 2.0 3.1 7.7 0.1 3.0 2 0 0 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.6 KFM63692.1 - 2.9e-16 59.5 0.1 3.2e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63692.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63694.1 - 5.9e-16 58.5 0.1 6.5e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63694.1 - 8.4e-16 58.0 6.5 1.5e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63694.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63694.1 - 0.003 17.3 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63694.1 - 0.017 15.2 0.1 0.068 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM63694.1 - 0.037 14.0 0.4 0.037 14.0 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM63695.1 - 2.1e-16 59.9 3.8 5.9e-16 58.5 2.2 2.4 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM63695.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63695.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63695.1 - 0.0025 17.6 0.6 0.0078 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63695.1 - 2 9.1 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain PTB PF08416.13 KFM63697.1 - 1.9e-09 37.8 0.0 3.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.28 KFM63697.1 - 3.5e-06 26.5 0.0 7.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM63697.1 - 0.00041 20.1 0.0 0.0009 19.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.23 KFM63697.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) MLTR_LBD PF17765.1 KFM63697.1 - 10 6.2 9.5 13 5.9 0.1 2.9 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain zf-C2H2 PF00096.26 KFM63698.1 - 1e-35 120.2 75.2 8.1e-06 26.0 0.6 9.2 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM63698.1 - 1.2e-33 114.0 60.7 4.4e-06 26.9 0.4 10.3 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM63698.1 - 1.2e-29 100.4 69.8 0.00037 21.1 0.3 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM63698.1 - 1.1e-20 73.3 61.3 0.00061 20.1 0.4 9.0 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63698.1 - 3.2e-13 49.6 57.0 0.005 17.1 0.5 8.7 9 0 0 9 9 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM63698.1 - 3.6e-09 36.4 66.0 0.088 12.8 0.6 9.2 9 0 0 9 9 9 7 C2H2-type zinc finger zf-Di19 PF05605.12 KFM63698.1 - 1.6e-07 31.5 41.3 0.0077 16.5 3.1 5.7 4 1 2 6 6 6 5 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFM63698.1 - 6.5e-06 26.3 6.4 1.5 9.2 0.0 6.1 3 3 2 5 5 5 1 BolA-like protein zf-C2HC_2 PF13913.6 KFM63698.1 - 0.005 16.7 27.6 0.63 10.0 0.5 7.2 7 0 0 7 7 6 3 zinc-finger of a C2HC-type GAGA PF09237.11 KFM63698.1 - 0.013 15.2 7.9 18 5.2 0.0 5.3 5 1 0 5 5 5 0 GAGA factor zf-C2H2_11 PF16622.5 KFM63698.1 - 0.038 13.8 0.3 0.038 13.8 0.3 7.7 9 0 0 9 9 8 0 zinc-finger C2H2-type DUF2256 PF10013.9 KFM63698.1 - 0.049 13.8 29.6 10 6.3 0.1 8.2 9 0 0 9 9 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Acetyltransf_16 PF05301.11 KFM63698.1 - 0.069 12.9 0.9 18 5.0 0.0 2.9 2 1 1 3 3 3 0 GNAT acetyltransferase, Mec-17 zf_UBZ PF18439.1 KFM63698.1 - 0.13 11.9 28.9 4.6 6.9 0.2 7.7 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM63698.1 - 0.37 11.1 45.4 8.8 6.7 2.2 8.3 1 1 5 7 7 6 0 C2H2 type zinc-finger (2 copies) DUF5318 PF17249.2 KFM63698.1 - 0.94 9.3 9.2 1 9.1 0.2 3.8 1 1 3 4 4 4 0 Family of unknown function (DUF5318) zf-C2H2_8 PF15909.5 KFM63698.1 - 2 8.7 32.7 4.4 7.7 2.8 5.3 1 1 4 5 5 5 0 C2H2-type zinc ribbon FYVE PF01363.21 KFM63698.1 - 8.2 6.7 41.5 0.14 12.3 6.1 6.2 3 2 2 5 5 4 0 FYVE zinc finger HNH PF01844.23 KFM63698.1 - 8.7 6.6 38.2 1.2 9.4 0.2 8.3 9 0 0 9 9 9 0 HNH endonuclease zf-H2C2_2 PF13465.6 KFM63699.1 - 2.1e-40 135.4 68.0 8.5e-06 26.0 0.4 10.3 10 1 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63699.1 - 3.2e-39 131.2 74.2 1.6e-05 25.1 2.9 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63699.1 - 2.4e-30 102.6 65.6 0.00011 22.7 0.3 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM63699.1 - 8.4e-21 73.7 53.8 0.0015 18.9 1.7 9.1 9 0 0 9 9 9 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63699.1 - 1.5e-17 63.3 48.8 1.2e-05 25.5 0.4 8.9 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM63699.1 - 4.3e-08 33.3 1.7 1.9 8.8 0.1 5.4 3 2 2 5 5 5 1 BolA-like protein zf-C2H2_6 PF13912.6 KFM63699.1 - 6.6e-08 32.4 64.2 0.055 13.5 0.5 9.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf-Di19 PF05605.12 KFM63699.1 - 2.5e-05 24.5 41.1 0.013 15.8 3.2 5.9 3 1 4 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFM63699.1 - 0.0025 17.5 4.1 0.036 13.8 0.2 8.1 9 0 0 9 9 9 2 zinc-finger C2H2-type FYVE PF01363.21 KFM63699.1 - 0.0034 17.5 33.9 0.41 10.8 9.8 6.1 1 1 5 6 6 6 2 FYVE zinc finger GAGA PF09237.11 KFM63699.1 - 0.0041 16.9 3.4 49 3.8 0.0 4.6 5 0 0 5 5 5 0 GAGA factor Zn-ribbon_8 PF09723.10 KFM63699.1 - 0.025 14.7 30.3 0.13 12.4 0.8 6.1 5 2 2 7 7 7 0 Zinc ribbon domain zf-C2HE PF16278.5 KFM63699.1 - 0.029 14.8 0.8 0.029 14.8 0.8 7.3 3 2 5 8 8 7 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.5 KFM63699.1 - 0.05 14.4 27.0 0.74 10.6 0.9 5.1 3 2 1 5 5 5 0 zinc-ribbon family LMSTEN PF07988.12 KFM63699.1 - 0.088 12.3 0.1 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 LMSTEN motif zf_UBZ PF18439.1 KFM63699.1 - 0.12 12.0 28.8 0.67 9.6 0.1 7.6 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 KFM63699.1 - 0.16 11.9 28.1 2.3 8.2 2.0 7.2 6 3 2 8 8 8 0 Probable zinc-ribbon domain HypA PF01155.19 KFM63699.1 - 0.16 12.0 21.2 1.9 8.5 2.4 4.4 1 1 4 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_1 PF00130.22 KFM63699.1 - 0.18 11.7 33.5 1.4 8.9 2.1 7.2 4 3 3 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MYST PF17772.1 KFM63699.1 - 0.19 11.4 38.5 0.46 10.1 0.2 8.2 4 3 5 9 9 9 0 MYST family zinc finger domain zf-C2H2_8 PF15909.5 KFM63699.1 - 0.25 11.6 28.3 0.81 10.0 3.0 4.6 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf-Dof PF02701.15 KFM63699.1 - 0.32 11.2 21.2 8 6.7 0.0 6.1 5 1 2 7 7 7 0 Dof domain, zinc finger zf-FCS PF06467.14 KFM63699.1 - 3.8 7.5 29.8 12 6.0 0.1 7.6 6 2 2 8 8 8 0 MYM-type Zinc finger with FCS sequence motif XPA_N PF01286.18 KFM63699.1 - 7 6.8 35.6 5.8 7.0 0.2 8.1 9 0 0 9 9 9 0 XPA protein N-terminal zinc-ribbons_6 PF07191.12 KFM63699.1 - 7.4 6.6 28.6 23 5.1 1.1 6.3 2 2 3 5 5 5 0 zinc-ribbons T-box PF00907.22 KFM63700.1 - 2e-86 289.0 1.8 2.3e-86 288.8 1.8 1.0 1 0 0 1 1 1 1 T-box Adap_comp_sub PF00928.21 KFM63701.1 - 1.1e-15 57.8 0.0 1.2e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 KFM63701.1 - 4.2e-05 23.1 0.0 4.8e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain RGS PF00615.19 KFM63702.1 - 8.9e-35 119.5 2.2 8.9e-35 119.5 2.2 2.1 3 0 0 3 3 3 1 Regulator of G protein signaling domain RGS_DHEX PF18148.1 KFM63702.1 - 2.6e-32 110.9 1.3 6.9e-32 109.5 1.3 1.8 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain G-gamma PF00631.22 KFM63702.1 - 1.6e-10 40.8 0.1 1.7e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 GGL domain DUF4734 PF15881.5 KFM63702.1 - 0.0092 16.1 0.1 0.035 14.3 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4734) RGS-like PF09128.11 KFM63702.1 - 0.042 13.6 0.6 0.093 12.4 0.1 1.9 2 1 0 2 2 2 0 Regulator of G protein signalling-like domain BCDHK_Adom3 PF10436.9 KFM63702.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase UCH PF00443.29 KFM63703.1 - 1.9e-26 93.1 0.0 2.2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM63703.1 - 0.0014 18.3 1.1 0.023 14.3 0.7 2.2 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase CmcI PF04989.12 KFM63703.1 - 0.12 12.0 0.9 0.46 10.2 0.0 2.2 3 0 0 3 3 3 0 Cephalosporin hydroxylase DUSP PF06337.12 KFM63705.1 - 1.9e-14 54.0 0.0 2.8e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 DUSP domain SCAN PF02023.17 KFM63707.1 - 0.00027 20.7 0.0 0.00057 19.6 0.0 1.5 1 0 0 1 1 1 1 SCAN domain zf-CCHC_4 PF14392.6 KFM63707.1 - 0.0052 16.5 0.4 0.014 15.2 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CHC2 PF01807.20 KFM63707.1 - 0.036 13.9 0.2 0.071 12.9 0.2 1.5 1 0 0 1 1 1 0 CHC2 zinc finger Phage_sheath_1C PF17482.2 KFM63707.1 - 0.12 12.4 0.4 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Phage tail sheath C-terminal domain MRNIP PF15749.5 KFM63707.1 - 1.5 9.6 7.4 2.5 8.9 0.2 2.3 1 1 1 2 2 2 0 MRN-interacting protein zf-CCHC PF00098.23 KFM63707.1 - 1.7 8.8 5.2 0.31 11.2 1.5 1.7 2 0 0 2 2 2 0 Zinc knuckle p450 PF00067.22 KFM63709.1 - 0.00073 18.4 0.3 0.00073 18.4 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 KBP_C PF12309.8 KFM63712.1 - 6.8e-99 331.8 7.0 6.8e-99 331.8 7.0 1.7 2 0 0 2 2 2 1 KIF-1 binding protein C terminal TPR_12 PF13424.6 KFM63712.1 - 0.00032 20.9 6.6 0.033 14.5 1.5 3.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM63712.1 - 0.0023 17.7 1.8 2.5 8.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM63712.1 - 0.011 15.7 2.4 1.4 9.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM63712.1 - 0.014 15.2 0.9 0.014 15.2 0.9 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM63712.1 - 0.15 13.0 0.0 2.8 9.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM63712.1 - 0.52 11.1 2.6 3.9 8.3 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM63712.1 - 8.8 6.7 20.0 0.12 12.6 0.7 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DDE_Tnp_IS1595 PF12762.7 KFM63713.1 - 3.1e-09 37.0 0.0 3.5e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF1126 PF06565.12 KFM63715.1 - 1.6e-06 27.9 0.1 2.9e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 DUF1126 PH-like domain DUF1126 PF06565.12 KFM63716.1 - 7.4e-07 29.0 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 DUF1126 PH-like domain FlaC_arch PF05377.11 KFM63718.1 - 0.002 18.5 8.5 0.025 15.0 1.2 2.5 1 1 2 3 3 3 2 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KFM63718.1 - 0.014 15.4 4.3 0.019 15.0 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1359 PF07097.11 KFM63718.1 - 0.017 15.4 0.5 0.06 13.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1359) Transcrip_act PF04949.13 KFM63718.1 - 0.044 13.7 7.5 0.052 13.4 7.5 1.1 1 0 0 1 1 1 0 Transcriptional activator Tropomyosin PF00261.20 KFM63718.1 - 0.13 11.6 10.5 0.15 11.4 10.5 1.1 1 0 0 1 1 1 0 Tropomyosin Lant_dehydr_C PF14028.6 KFM63718.1 - 0.16 11.5 0.1 0.16 11.5 0.1 1.0 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Apolipoprotein PF01442.18 KFM63718.1 - 0.18 11.7 4.7 0.39 10.6 4.7 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1640 PF07798.11 KFM63718.1 - 0.18 11.8 8.8 1 9.4 8.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) WXG100 PF06013.12 KFM63718.1 - 0.29 11.4 2.9 14 6.0 0.1 2.3 1 1 0 2 2 2 0 Proteins of 100 residues with WXG YabA PF06156.13 KFM63718.1 - 0.33 11.6 9.2 0.58 10.8 0.8 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF3213 PF11491.8 KFM63718.1 - 0.33 11.2 6.1 0.1 12.8 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3213) NEMO PF11577.8 KFM63718.1 - 0.41 10.7 10.4 0.83 9.7 0.6 2.5 2 1 0 2 2 2 0 NF-kappa-B essential modulator NEMO XhlA PF10779.9 KFM63718.1 - 0.43 10.8 6.1 0.13 12.4 0.5 2.2 1 1 1 2 2 2 0 Haemolysin XhlA COG2 PF06148.11 KFM63718.1 - 0.95 9.6 7.5 4 7.5 0.3 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.11 KFM63718.1 - 1.7 8.9 7.6 2.8 8.1 0.2 2.0 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Fcf1 PF04900.12 KFM63719.1 - 1.9e-20 73.1 0.5 5.4e-20 71.6 0.0 1.9 2 1 0 2 2 2 1 Fcf1 Neisseria_TspB PF05616.13 KFM63719.1 - 0.052 12.0 0.0 0.21 10.1 0.0 1.8 1 1 0 2 2 2 0 Neisseria meningitidis TspB protein Ldl_recept_a PF00057.18 KFM63720.1 - 0.25 11.6 1.6 0.47 10.7 1.6 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 KFM63721.1 - 1.6e-09 37.8 6.5 4.4e-09 36.4 6.5 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A EphA2_TM PF14575.6 KFM63721.1 - 0.14 13.0 0.0 0.31 12.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3536 PF12055.8 KFM63721.1 - 0.17 11.2 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) DDE_3 PF13358.6 KFM63723.1 - 2.7e-06 27.2 0.1 2.7e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease V-set PF07686.17 KFM63724.1 - 0.06 13.5 0.0 0.06 13.5 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM63725.1 - 8.2e-08 32.2 0.3 7.4e-07 29.1 0.1 2.1 1 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFM63725.1 - 4.5e-05 23.4 1.1 0.0044 17.1 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM63725.1 - 5.8e-05 23.6 1.6 0.0011 19.5 0.3 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM63725.1 - 0.00084 19.6 0.4 0.14 12.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain LpxD PF04613.14 KFM63725.1 - 0.031 14.0 0.1 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Ig_3 PF13927.6 KFM63726.1 - 8.2e-37 125.7 5.7 2.6e-10 40.7 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 KFM63726.1 - 2.1e-32 111.0 6.9 2.5e-12 46.7 0.0 5.0 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM63726.1 - 1.2e-24 86.4 0.2 8.3e-06 26.1 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFM63726.1 - 3.3e-23 81.6 3.8 2.2e-09 37.3 0.0 4.6 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFM63726.1 - 1.7e-09 37.8 2.7 0.0067 16.6 0.1 5.2 4 3 1 5 5 5 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM63726.1 - 4.2e-06 26.2 0.1 0.047 13.3 0.0 3.6 4 0 0 4 4 4 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM63726.1 - 0.00028 20.8 0.1 2.8 8.0 0.0 4.7 4 2 0 4 4 4 1 C17orf99 Ig domain Ig_4 PF16680.5 KFM63726.1 - 0.00054 20.2 0.1 0.37 11.1 0.0 3.5 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain PKD_3 PF16820.5 KFM63726.1 - 0.00056 19.6 0.6 0.31 10.8 0.4 2.5 2 0 0 2 2 2 2 PKD-like domain Izumo-Ig PF16706.5 KFM63726.1 - 0.0043 17.1 0.5 5.1 7.2 0.0 3.9 3 2 2 5 5 5 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 KFM63726.1 - 0.16 12.2 0.3 15 5.9 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin C2-set domain V-set_CD47 PF08204.11 KFM63726.1 - 0.84 9.6 7.3 7.3 6.6 0.1 4.1 3 2 2 5 5 5 0 CD47 immunoglobulin-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63728.1 - 1.2e-16 60.7 1.9 4.7e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63728.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM63729.1 - 5.5e-09 36.0 0.0 1.5e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM63729.1 - 0.0065 16.0 0.3 0.0065 16.0 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger C2H2-type PepX_C PF08530.10 KFM63729.1 - 0.2 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain ANF_receptor PF01094.28 KFM63730.1 - 3.2e-06 26.5 0.0 3.7e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peptidase_M4 PF01447.18 KFM63730.1 - 0.042 14.4 0.1 0.052 14.0 0.1 1.1 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain HTH_Tnp_Tc3_2 PF01498.18 KFM63731.1 - 3.7e-15 55.9 0.9 6.7e-15 55.1 0.9 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63731.1 - 4.6e-13 49.2 0.0 7.4e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM63731.1 - 3.4e-05 24.4 7.2 0.00021 21.8 2.8 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 KFM63731.1 - 0.02 14.5 0.2 0.02 14.5 0.2 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM63731.1 - 0.031 14.3 0.3 0.073 13.2 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase PX PF00787.24 KFM63732.1 - 8.3e-16 58.0 0.8 9.7e-16 57.8 0.8 1.1 1 0 0 1 1 1 1 PX domain Galactosyl_T PF01762.21 KFM63733.1 - 3.9e-44 150.8 4.0 4.9e-28 98.3 1.9 2.3 2 0 0 2 2 2 2 Galactosyltransferase zf-H2C2_2 PF13465.6 KFM63734.1 - 1.2e-82 268.9 120.3 4.3e-08 33.2 0.6 15.1 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63734.1 - 7e-55 180.5 144.0 4.1e-06 27.0 1.9 14.1 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63734.1 - 8.6e-43 141.3 135.2 0.00066 20.3 1.1 14.1 14 0 0 14 14 14 14 C2H2-type zinc finger zf-met PF12874.7 KFM63734.1 - 2.1e-25 88.3 110.1 0.0042 17.4 0.7 14.2 14 0 0 14 14 14 12 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM63734.1 - 1.2e-18 66.5 65.6 0.015 15.1 0.5 13.8 13 0 0 13 13 13 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM63734.1 - 9.3e-12 44.9 89.2 0.11 12.9 0.1 13.8 14 0 0 14 14 14 8 Zinc-finger double-stranded RNA-binding zf-RRPl_C4 PF17026.5 KFM63734.1 - 0.0022 18.1 65.0 0.87 9.7 7.3 6.1 1 1 5 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type Complex1_49kDa PF00346.19 KFM63734.1 - 0.014 14.5 3.8 0.25 10.4 0.4 2.8 2 1 1 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-C2H2_6 PF13912.6 KFM63734.1 - 0.016 15.2 117.1 0.099 12.7 1.2 14.9 14 2 0 14 14 14 0 C2H2-type zinc finger zf-DBF PF07535.12 KFM63734.1 - 0.016 15.3 67.1 2.7 8.2 0.3 13.2 12 1 1 13 13 13 0 DBF zinc finger Tox-HNH-HHH PF15637.6 KFM63734.1 - 0.017 15.2 3.1 41 4.4 0.0 5.1 1 1 2 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif BolA PF01722.18 KFM63734.1 - 0.037 14.3 31.0 9.2 6.6 0.1 8.2 1 1 7 9 9 9 0 BolA-like protein GAGA PF09237.11 KFM63734.1 - 0.045 13.6 44.3 0.67 9.8 0.1 10.6 1 1 11 13 13 13 0 GAGA factor zf-C2H2_9 PF16293.5 KFM63734.1 - 0.057 13.3 66.4 0.4 10.6 0.1 13.1 3 2 11 14 14 14 0 C2H2 type zinc-finger (1 copy) zf-C4_ClpX PF06689.13 KFM63734.1 - 0.11 12.5 0.3 0.11 12.5 0.3 9.6 10 3 3 13 13 10 0 ClpX C4-type zinc finger zf-C2HC_2 PF13913.6 KFM63734.1 - 0.11 12.4 59.3 4.7 7.2 0.1 12.7 12 1 1 13 13 13 0 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM63734.1 - 0.19 11.8 55.6 9.5 6.4 0.1 12.8 9 5 5 14 14 14 0 Sec23/Sec24 zinc finger PqqA PF08042.11 KFM63734.1 - 0.58 10.3 3.1 5.3e+02 0.9 0.0 5.6 7 0 0 7 7 7 0 PqqA family C1_1 PF00130.22 KFM63734.1 - 0.74 9.8 95.4 1.3 9.0 2.8 12.3 6 4 6 12 12 12 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CTV_P23 PF04808.12 KFM63734.1 - 2.5 7.6 12.0 4.1 6.9 0.6 3.6 3 1 1 4 4 4 0 Citrus tristeza virus (CTV) P23 protein FYVE PF01363.21 KFM63734.1 - 2.9 8.1 86.2 0.2 11.8 11.3 7.6 1 1 6 7 7 6 0 FYVE zinc finger zf-H2C2_2 PF13465.6 KFM63735.1 - 4.8e-19 67.9 26.7 1.3e-08 34.9 0.2 4.2 5 0 0 5 5 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63735.1 - 5.1e-17 61.3 29.9 3.1e-05 24.2 0.9 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63735.1 - 5.2e-14 51.7 26.0 3.1e-05 24.4 0.8 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFM63735.1 - 2.7e-12 46.6 18.9 0.0031 17.8 1.0 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM63735.1 - 2.7e-08 33.9 13.0 0.019 15.2 0.5 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM63735.1 - 1.3e-06 28.1 7.9 0.0071 16.1 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM63735.1 - 1.5e-06 27.9 21.1 0.037 13.8 0.7 4.1 4 0 0 4 4 4 3 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 KFM63735.1 - 0.00023 21.0 1.8 0.00023 21.0 1.8 3.0 2 1 1 3 3 3 1 SprT-like zinc ribbon domain BolA PF01722.18 KFM63735.1 - 0.00074 19.7 1.0 1.2 9.4 0.3 2.9 1 1 2 3 3 3 1 BolA-like protein zf-C2H2_9 PF16293.5 KFM63735.1 - 0.0011 18.8 9.8 0.4 10.6 0.1 4.0 2 2 2 4 4 4 1 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM63735.1 - 0.0017 18.4 10.8 2.9 8.0 2.6 4.0 2 1 1 3 3 3 2 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM63735.1 - 0.0021 18.1 9.0 3.8 7.7 0.3 4.1 4 0 0 4 4 4 1 DBF zinc finger C1_1 PF00130.22 KFM63735.1 - 0.0026 17.6 15.9 0.12 12.2 0.4 3.9 3 1 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 KFM63735.1 - 0.0044 17.1 10.6 2.3 8.4 0.1 4.0 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFM63735.1 - 0.0046 16.5 13.5 0.22 11.1 0.2 3.9 2 1 2 4 4 4 2 MYST family zinc finger domain DZR PF12773.7 KFM63735.1 - 0.0088 16.1 6.1 4.8 7.3 6.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C2HC_2 PF13913.6 KFM63735.1 - 0.014 15.2 7.1 2.2 8.3 0.1 3.8 3 1 0 3 3 3 0 zinc-finger of a C2HC-type GAGA PF09237.11 KFM63735.1 - 0.019 14.7 3.7 1.7 8.5 0.0 3.5 1 1 3 4 4 4 0 GAGA factor Baculo_IE-1 PF05290.11 KFM63735.1 - 0.031 14.2 9.0 2.3 8.1 0.7 3.4 1 1 3 4 4 4 0 Baculovirus immediate-early protein (IE-0) zf-RRPl_C4 PF17026.5 KFM63735.1 - 0.037 14.1 10.4 0.14 12.3 6.5 2.2 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-Paramyx-P PF13008.7 KFM63735.1 - 0.044 13.3 1.9 18 4.9 0.0 3.3 3 0 0 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein zf-C2H2_6 PF13912.6 KFM63735.1 - 0.045 13.8 17.9 1.2 9.2 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFM63735.1 - 0.048 13.8 10.2 1.1 9.4 0.2 3.3 3 1 0 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 KFM63735.1 - 0.052 13.5 9.8 0.26 11.3 1.3 3.0 1 1 1 2 2 2 0 zinc-ribbons zinc_ribbon_15 PF17032.5 KFM63735.1 - 0.058 14.2 8.3 1.4 9.7 1.4 2.1 1 1 0 2 2 2 0 zinc-ribbon family FYVE_2 PF02318.16 KFM63735.1 - 0.06 13.6 8.7 0.49 10.6 1.3 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger zf-C2H2_2 PF12756.7 KFM63735.1 - 0.067 13.5 19.1 1.3 9.4 0.8 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF2757 PF10955.8 KFM63735.1 - 0.11 12.8 7.3 3.4 8.0 0.2 3.7 3 1 0 4 4 4 0 Protein of unknown function (DUF2757) zf-Dof PF02701.15 KFM63735.1 - 0.19 11.9 10.9 0.12 12.5 2.7 2.9 2 1 1 3 3 3 0 Dof domain, zinc finger zf-FPG_IleRS PF06827.14 KFM63735.1 - 0.46 10.4 11.4 1.1 9.2 2.3 3.6 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS ADK_lid PF05191.14 KFM63735.1 - 0.48 10.4 7.6 0.17 11.9 1.8 2.7 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-trcl PF13451.6 KFM63735.1 - 0.59 10.1 10.5 21 5.1 0.1 4.0 4 0 0 4 4 4 0 Probable zinc-ribbon domain zf_UBZ PF18439.1 KFM63735.1 - 0.64 9.7 12.4 6.2 6.5 0.1 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger HNH PF01844.23 KFM63735.1 - 0.79 9.9 12.3 2.2 8.5 0.1 4.0 4 0 0 4 4 4 0 HNH endonuclease Cas_CXXC_CXXC PF09706.10 KFM63735.1 - 1.2 9.4 12.9 9.5 6.5 0.1 3.7 1 1 4 5 5 5 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF5330 PF17264.2 KFM63735.1 - 1.9 8.6 3.6 7.6 6.6 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5330) FYDLN_acid PF09538.10 KFM63735.1 - 2.1 9.1 4.8 8.6 7.1 0.2 2.7 2 1 1 3 3 2 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_4 PF13717.6 KFM63735.1 - 2.8 7.9 12.7 7 6.7 0.4 4.0 4 0 0 4 4 4 0 zinc-ribbon domain C1_4 PF07975.12 KFM63735.1 - 3.8 7.8 13.8 3.2 8.0 2.5 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain Zf_RING PF16744.5 KFM63735.1 - 4 7.6 13.4 57 3.9 4.0 3.8 1 1 2 3 3 3 0 KIAA1045 RING finger Ribosomal_L37ae PF01780.19 KFM63735.1 - 8.1 6.6 7.9 3.7 7.7 0.3 2.9 1 1 2 3 3 3 0 Ribosomal L37ae protein family zf-H2C2_2 PF13465.6 KFM63736.1 - 1.9e-18 65.9 22.8 3e-07 30.6 1.3 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63736.1 - 1.1e-13 50.8 23.2 7.9e-06 26.1 1.3 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63736.1 - 2.8e-11 43.3 22.4 0.00083 20.0 1.2 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM63736.1 - 3e-08 33.8 16.8 0.0026 18.1 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 KFM63736.1 - 0.00041 20.1 7.0 0.028 14.2 0.1 3.0 1 1 2 3 3 3 1 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM63736.1 - 0.003 17.6 10.9 0.0065 16.6 10.9 1.5 1 1 0 1 1 1 1 FYVE zinc finger zf-C2H2_jaz PF12171.8 KFM63736.1 - 0.0049 17.1 10.8 0.64 10.4 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 KFM63736.1 - 0.03 14.4 8.1 4.3 7.5 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM63736.1 - 0.031 14.4 9.3 3.4 7.9 0.1 3.4 3 0 0 3 3 3 0 DBF zinc finger FYDLN_acid PF09538.10 KFM63736.1 - 0.032 14.9 3.8 0.5 11.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) C5HCH PF17982.1 KFM63736.1 - 0.033 14.3 11.7 0.89 9.8 3.4 3.2 1 1 2 3 3 3 0 NSD Cys-His rich domain C1_1 PF00130.22 KFM63736.1 - 0.035 14.0 14.8 1.6 8.7 0.3 3.2 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Herpes_ORF11 PF04797.13 KFM63736.1 - 0.037 12.8 0.1 0.042 12.7 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus dUTPase protein GAGA PF09237.11 KFM63736.1 - 0.047 13.5 2.7 2.2 8.1 0.1 2.8 1 1 2 3 3 3 0 GAGA factor zf-CRD PF17979.1 KFM63736.1 - 0.048 13.8 8.6 1.1 9.3 8.6 2.2 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-C2HC_2 PF13913.6 KFM63736.1 - 0.081 12.8 8.1 3.1 7.8 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type TRAF6_Z2 PF18048.1 KFM63736.1 - 0.12 12.5 9.0 19 5.5 2.7 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Guanylin PF02058.15 KFM63736.1 - 0.14 12.6 5.5 13 6.3 0.1 2.8 1 1 2 3 3 3 0 Guanylin precursor zf-RRPl_C4 PF17026.5 KFM63736.1 - 0.19 11.8 7.5 1.6 8.8 7.5 2.0 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_2 PF12756.7 KFM63736.1 - 0.21 11.9 18.1 0.62 10.4 1.0 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-MYND PF01753.18 KFM63736.1 - 0.24 11.5 8.2 0.1 12.7 2.0 2.5 1 1 0 2 2 2 0 MYND finger zf-C2H2_6 PF13912.6 KFM63736.1 - 0.25 11.4 24.2 0.49 10.4 2.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Dof PF02701.15 KFM63736.1 - 0.25 11.5 7.4 0.96 9.6 0.1 2.8 1 1 2 3 3 3 0 Dof domain, zinc finger zf-AN1 PF01428.16 KFM63736.1 - 0.74 10.0 12.0 0.62 10.3 2.0 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger ADK_lid PF05191.14 KFM63736.1 - 0.79 9.8 8.4 4.6 7.3 2.8 2.3 1 1 1 2 2 2 0 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM63736.1 - 1.7 8.3 10.1 29 4.4 0.1 3.1 3 0 0 3 3 3 0 MYST family zinc finger domain HNH PF01844.23 KFM63736.1 - 2.3 8.4 9.7 12 6.2 0.2 3.1 3 0 0 3 3 3 0 HNH endonuclease Vps39_2 PF10367.9 KFM63736.1 - 4.8 7.7 15.8 2.4 8.7 0.8 3.1 1 1 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-H2C2_2 PF13465.6 KFM63737.1 - 2.4e-80 261.6 93.0 1.7e-08 34.5 1.3 13.1 13 0 0 13 13 13 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63737.1 - 8.8e-46 151.9 112.5 3.5e-06 27.1 3.4 12.9 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63737.1 - 7.4e-38 126.0 106.0 0.00069 20.2 1.6 12.9 13 0 0 13 13 13 12 C2H2-type zinc finger zf-met PF12874.7 KFM63737.1 - 3.5e-18 65.3 94.5 0.028 14.8 2.8 13.3 13 0 0 13 13 13 9 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.15 KFM63737.1 - 1.9e-13 50.2 39.8 0.15 12.2 0.0 11.9 8 3 4 12 12 12 5 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KFM63737.1 - 3.4e-09 36.8 73.1 0.033 14.5 0.3 13.3 13 1 0 13 13 13 6 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM63737.1 - 7.1e-07 28.9 80.8 0.047 13.4 4.1 11.7 11 1 1 12 12 12 6 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFM63737.1 - 0.00048 19.9 52.6 0.6 10.0 0.1 11.3 4 4 8 12 12 12 2 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM63737.1 - 0.0035 17.6 19.4 12 6.3 1.0 7.3 2 2 4 6 6 6 0 BolA-like protein FYVE PF01363.21 KFM63737.1 - 0.012 15.7 69.7 2.4 8.3 8.7 7.1 1 1 5 6 6 6 0 FYVE zinc finger IGPD PF00475.18 KFM63737.1 - 0.034 14.4 3.3 1.1 9.5 0.0 3.5 2 1 0 3 3 3 0 Imidazoleglycerol-phosphate dehydratase zf-DBF PF07535.12 KFM63737.1 - 0.046 13.8 59.4 2 8.6 0.1 12.2 12 1 1 13 13 13 0 DBF zinc finger GAGA PF09237.11 KFM63737.1 - 0.094 12.5 35.6 2.1 8.2 0.2 8.9 2 2 8 11 11 11 0 GAGA factor C1_1 PF00130.22 KFM63737.1 - 0.095 12.6 79.1 3.9 7.4 0.8 11.3 5 4 3 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 KFM63737.1 - 0.14 12.3 56.8 1.6 8.9 5.8 5.5 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type Complex1_49kDa PF00346.19 KFM63737.1 - 0.16 11.0 1.4 0.91 8.6 0.1 2.3 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit PqqA PF08042.11 KFM63737.1 - 0.99 9.5 3.8 4e+02 1.3 0.0 5.3 6 0 0 6 6 6 0 PqqA family zf-C2H2_6 PF13912.6 KFM63737.1 - 1.5 8.9 96.1 0.45 10.6 1.2 13.2 14 0 0 14 14 13 0 C2H2-type zinc finger YyzF PF14116.6 KFM63737.1 - 6.8 6.8 49.9 32 4.6 0.1 12.1 13 0 0 13 13 13 0 YyzF-like protein Helicase_C PF00271.31 KFM63738.1 - 2.2e-12 47.3 0.1 2.2e-12 47.3 0.1 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF19 PF01579.18 KFM63740.1 - 0.12 12.1 11.5 0.06 13.1 4.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF19) zf-CCHC PF00098.23 KFM63741.1 - 3.8e-06 26.7 1.5 5e-06 26.3 1.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM63741.1 - 0.0051 16.5 0.6 0.0094 15.6 0.6 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Prolamin_like PF05617.11 KFM63741.1 - 0.053 13.7 0.0 0.058 13.6 0.0 1.1 1 0 0 1 1 1 0 Prolamin-like zf-CCHC_2 PF13696.6 KFM63741.1 - 0.14 12.0 3.0 0.21 11.4 3.0 1.3 1 0 0 1 1 1 0 Zinc knuckle DDE_3 PF13358.6 KFM63742.1 - 2e-10 40.6 0.0 2.9e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63742.1 - 7.9e-06 26.0 1.7 1.5e-05 25.1 1.7 1.4 1 0 0 1 1 1 1 Transposase HLH PF00010.26 KFM63743.1 - 7e-16 57.9 0.2 1.1e-15 57.3 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Bax1-I PF01027.20 KFM63745.1 - 1e-45 156.1 31.8 1.2e-45 156.0 31.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2518 PF10726.9 KFM63745.1 - 0.077 12.7 4.0 0.19 11.4 4.0 1.8 1 0 0 1 1 1 0 Protein of function (DUF2518) BaxI_1 PF12811.7 KFM63745.1 - 1.5 8.4 24.5 2.6 7.5 24.5 1.3 1 1 0 1 1 1 0 Bax inhibitor 1 like PAP2 PF01569.21 KFM63746.1 - 2.2e-08 33.9 3.0 2.2e-08 33.9 3.0 2.0 3 0 0 3 3 3 1 PAP2 superfamily Deltameth_res PF16020.5 KFM63746.1 - 0.039 13.8 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Deltamethrin resistance RNase_T PF00929.24 KFM63747.1 - 3e-11 44.1 0.0 3.3e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DDE_Tnp_1_7 PF13843.6 KFM63748.1 - 4.3e-08 32.8 0.2 4.6e-08 32.8 0.2 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF5454 PF17535.2 KFM63748.1 - 0.0031 16.9 0.5 0.0031 16.9 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5454) zf-CpG_bind_C PF12269.8 KFM63749.1 - 7.7e-100 333.5 11.5 7.7e-100 333.5 11.5 2.6 3 1 1 4 4 4 1 CpG binding protein zinc finger C terminal domain zf-CXXC PF02008.20 KFM63749.1 - 3e-15 56.0 22.6 3e-15 56.0 22.6 3.5 4 0 0 4 4 4 1 CXXC zinc finger domain PHD PF00628.29 KFM63749.1 - 1e-10 41.3 7.2 1e-10 41.3 7.2 4.8 5 1 0 5 5 5 1 PHD-finger CDC45 PF02724.14 KFM63749.1 - 2.8 6.1 13.4 5.7 5.1 13.4 1.5 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M13 PF01431.21 KFM63750.1 - 1.6e-06 27.9 0.0 1.7e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM63751.1 - 3.3e-67 227.8 9.3 4.9e-64 217.4 9.3 2.0 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM63752.1 - 3.3e-30 105.2 0.5 4.7e-30 104.7 0.5 1.2 1 0 0 1 1 1 1 Peptidase family M13 RNase_H PF00075.24 KFM63752.1 - 3.6e-10 40.2 0.0 7.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM63752.1 - 5e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Tctex-1 PF03645.13 KFM63753.1 - 4.5e-16 59.0 0.2 7.4e-16 58.3 0.0 1.4 2 0 0 2 2 2 1 Tctex-1 family SSP160 PF06933.11 KFM63753.1 - 0.036 12.3 0.5 0.041 12.1 0.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Guanylate_kin PF00625.21 KFM63754.1 - 1.3e-49 168.4 0.0 1.7e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KFM63754.1 - 5.7e-11 41.9 0.0 1.1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM63754.1 - 1.3e-08 34.3 1.7 9.4e-08 31.6 1.7 2.2 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM63754.1 - 3.9e-05 23.4 0.3 0.00011 22.0 0.3 1.7 1 1 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 KFM63755.1 - 0.0065 16.8 0.0 0.0079 16.5 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.25 KFM63756.1 - 3.3e-67 226.6 0.0 3.8e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM63756.1 - 4.2e-30 104.9 0.0 5e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM63756.1 - 1.9e-05 24.2 0.0 0.0001 21.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFM63756.1 - 0.00052 18.9 0.0 0.00077 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase OATP PF03137.20 KFM63758.1 - 7e-84 282.1 0.5 8.6e-84 281.8 0.5 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFM63758.1 - 1.9e-12 46.8 11.0 3.3e-08 32.8 1.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Cation_efflux PF01545.21 KFM63758.1 - 0.0065 16.2 1.0 0.13 11.9 0.2 2.3 2 0 0 2 2 2 1 Cation efflux family HTH_24 PF13412.6 KFM63759.1 - 0.00019 20.9 0.1 0.00034 20.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 KFM63759.1 - 0.00052 20.6 0.0 0.00069 20.2 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_9 PF08221.11 KFM63759.1 - 0.02 15.0 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_26 PF13443.6 KFM63759.1 - 0.039 14.4 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 KFM63759.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_37 PF13744.6 KFM63759.1 - 0.061 13.3 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF977 PF06163.11 KFM63759.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_Tnp_Tc3_2 PF01498.18 KFM63759.1 - 0.11 12.8 0.1 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 Transposase Sigma70_r4 PF04545.16 KFM63759.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Striatin PF08232.12 KFM63760.1 - 4e-45 154.2 4.5 4e-45 154.2 4.5 3.0 2 2 0 2 2 2 1 Striatin family WD40 PF00400.32 KFM63760.1 - 8.7e-40 134.0 10.8 7e-08 33.0 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM63760.1 - 3.8e-09 36.7 0.1 0.09 13.1 0.0 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM63760.1 - 0.0022 16.7 0.6 2 7.0 0.0 2.7 2 1 0 3 3 3 2 Nucleoporin Nup120/160 DUF4482 PF14818.6 KFM63760.1 - 2.2 9.2 7.9 0.19 12.6 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) tRNA-synt_2b PF00587.25 KFM63761.1 - 1.8e-39 135.6 0.0 3.2e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFM63761.1 - 1.4e-19 70.3 2.1 4e-19 68.8 0.5 2.6 2 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain VGCC_alpha2 PF08473.11 KFM63762.1 - 7.5e-08 31.6 1.8 7.7e-08 31.5 1.8 1.1 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd TrbM PF07424.11 KFM63762.1 - 0.077 12.9 0.8 0.096 12.6 0.8 1.2 1 0 0 1 1 1 0 TrbM VGCC_alpha2 PF08473.11 KFM63763.1 - 4.1e-12 45.6 0.2 4.5e-12 45.5 0.2 1.0 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VGCC_alpha2 PF08473.11 KFM63764.1 - 3.7e-07 29.3 0.1 4.5e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd dCache_1 PF02743.18 KFM63764.1 - 0.038 13.8 0.2 0.097 12.4 0.0 1.7 2 0 0 2 2 2 0 Cache domain PMBR PF09373.10 KFM63764.1 - 0.16 12.2 0.9 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Pseudomurein-binding repeat dCache_1 PF02743.18 KFM63765.1 - 2.8e-09 37.1 0.0 5e-09 36.3 0.0 1.3 1 1 0 1 1 1 1 Cache domain VWA_N PF08399.11 KFM63767.1 - 1.1e-31 109.8 0.4 1.3e-31 109.7 0.4 1.0 1 0 0 1 1 1 1 VWA N-terminal Nt_Gln_amidase PF09764.9 KFM63767.1 - 0.086 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 N-terminal glutamine amidase EF-hand_1 PF00036.32 KFM63768.1 - 6.3e-25 84.8 1.7 2e-07 30.1 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFM63768.1 - 8.8e-22 77.4 1.3 5.3e-17 62.0 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM63768.1 - 2.5e-20 70.6 0.8 2.9e-05 23.6 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFM63768.1 - 1e-16 59.6 0.4 3.2e-06 26.4 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFM63768.1 - 3.8e-14 52.3 1.6 7.4e-09 35.3 0.5 3.2 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM63768.1 - 4.6e-07 30.1 0.3 0.032 14.5 0.1 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFM63768.1 - 3.5e-06 26.8 0.5 0.016 15.1 0.0 2.6 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KFM63768.1 - 0.00061 20.1 0.1 0.016 15.5 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 KFM63768.1 - 0.0031 17.7 0.1 0.27 11.5 0.0 2.7 2 1 1 3 3 3 1 Dockerin type I domain EF-hand_4 PF12763.7 KFM63768.1 - 0.0064 16.4 0.5 17 5.4 0.0 3.1 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 KFM63768.1 - 0.014 15.6 0.2 5.4 7.2 0.1 2.3 1 1 1 2 2 2 0 p25-alpha Guanylate_kin PF00625.21 KFM63769.1 - 3.8e-46 157.1 0.0 5.5e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KFM63769.1 - 5.4e-08 32.4 0.0 1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM63769.1 - 4.6e-06 26.1 0.0 1.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM63769.1 - 0.00083 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Snf7 PF03357.21 KFM63770.1 - 1e-29 103.4 6.9 1.9e-29 102.5 6.9 1.4 1 0 0 1 1 1 1 Snf7 Cluap1 PF10234.9 KFM63770.1 - 0.0038 16.7 5.9 0.53 9.6 0.2 2.1 2 0 0 2 2 2 2 Clusterin-associated protein-1 WD-3 PF09765.9 KFM63770.1 - 0.011 15.0 3.1 0.052 12.9 0.1 2.2 1 1 1 2 2 2 0 WD-repeat region DUF4872 PF16169.5 KFM63770.1 - 0.031 14.0 0.2 0.061 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) PHM7_cyt PF14703.6 KFM63770.1 - 0.054 13.7 1.5 0.11 12.7 1.5 1.6 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Flagellin_N PF00669.20 KFM63770.1 - 0.08 13.1 1.2 11 6.1 0.5 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Pup PF05639.11 KFM63770.1 - 0.12 13.3 0.8 2.9 8.9 0.1 3.0 2 0 0 2 2 2 0 Pup-like protein TINF2_N PF14973.6 KFM63770.1 - 0.14 12.5 2.1 0.52 10.6 1.8 2.2 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Not3 PF04065.15 KFM63770.1 - 0.19 11.1 6.0 0.034 13.6 1.2 2.1 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF1664 PF07889.12 KFM63770.1 - 0.25 11.4 5.2 1.4 8.9 0.1 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KFM63770.1 - 2.5 8.6 12.5 33 5.0 7.1 3.2 2 1 0 2 2 2 0 Apg6 coiled-coil region FlgN PF05130.12 KFM63770.1 - 2.8 8.5 11.6 0.13 12.7 2.9 2.8 1 1 2 3 3 3 0 FlgN protein PCRF PF03462.18 KFM63770.1 - 7.6 6.4 7.1 1.4 8.7 1.4 2.2 1 1 1 2 2 2 0 PCRF domain UPF0242 PF06785.11 KFM63770.1 - 8.9 6.4 8.9 23 5.0 1.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus zf-H2C2_2 PF13465.6 KFM63771.1 - 8.2e-18 64.0 17.6 1.2e-08 34.9 1.8 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63771.1 - 8.6e-13 48.0 18.0 1.8e-05 24.9 3.0 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63771.1 - 2.4e-09 37.2 21.8 0.0023 18.6 2.3 3.5 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM63771.1 - 2.8e-05 24.3 5.7 0.19 12.1 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM63771.1 - 5.3e-05 23.0 6.6 0.3 11.0 0.5 3.3 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFM63771.1 - 0.00014 21.8 19.0 0.084 12.9 1.6 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-SNAP50_C PF12251.8 KFM63771.1 - 0.0075 16.0 1.6 0.0075 16.0 1.6 1.7 1 1 1 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal zf-met PF12874.7 KFM63771.1 - 0.0084 16.5 2.7 0.0084 16.5 2.7 2.7 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf-AN1 PF01428.16 KFM63771.1 - 0.014 15.5 8.6 2.2 8.5 0.2 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger DUF2180 PF09947.9 KFM63771.1 - 0.021 14.8 3.5 0.035 14.1 3.5 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_2 PF12756.7 KFM63771.1 - 0.021 15.2 12.6 0.31 11.4 1.5 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM63771.1 - 0.03 14.5 3.7 2.7 8.2 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_1 PF00130.22 KFM63771.1 - 0.04 13.8 7.8 4.3 7.3 3.0 2.9 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MYST PF17772.1 KFM63771.1 - 0.05 13.2 5.3 0.085 12.5 0.2 2.7 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2H2_3rep PF18868.1 KFM63771.1 - 0.067 13.9 4.7 10 6.8 0.6 2.9 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 KFM63771.1 - 0.12 12.7 5.7 0.16 12.3 5.7 1.3 1 0 0 1 1 1 0 C2H2-type zinc ribbon GAGA PF09237.11 KFM63771.1 - 0.13 12.1 1.6 6.9 6.6 0.1 2.2 1 1 1 2 2 2 0 GAGA factor zf-CHCC PF10276.9 KFM63771.1 - 0.13 12.3 4.4 2.9 8.0 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger domain HNH PF01844.23 KFM63771.1 - 0.14 12.4 7.5 6.1 7.1 0.1 3.1 3 0 0 3 3 3 0 HNH endonuclease Zf_RING PF16744.5 KFM63771.1 - 0.14 12.3 7.3 1.8 8.7 0.2 3.0 1 1 2 3 3 3 0 KIAA1045 RING finger Zn_ribbon_SprT PF17283.2 KFM63771.1 - 0.17 11.8 5.5 0.86 9.6 1.6 2.4 1 1 2 3 3 3 0 SprT-like zinc ribbon domain zf-trcl PF13451.6 KFM63771.1 - 0.19 11.6 2.8 38 4.3 0.0 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain LIM PF00412.22 KFM63771.1 - 0.28 11.5 5.6 5.6 7.3 1.7 2.5 1 1 0 1 1 1 0 LIM domain FYVE PF01363.21 KFM63771.1 - 0.37 11.0 12.6 0.85 9.8 5.0 2.2 1 1 1 2 2 2 0 FYVE zinc finger PyrI_C PF02748.15 KFM63771.1 - 0.65 9.9 7.0 3.3 7.7 0.3 2.9 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 KFM63771.1 - 0.97 9.6 8.1 9.6 6.4 0.3 3.0 2 1 1 3 3 3 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 KFM63771.1 - 2 8.2 10.3 13 5.7 0.2 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain Desulfoferrod_N PF06397.12 KFM63771.1 - 3.5 7.3 8.6 7.3 6.3 0.3 3.1 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-C2H2 PF00096.26 KFM63772.1 - 1.2e-10 41.2 15.4 6.3e-06 26.4 7.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM63772.1 - 5.1e-09 36.2 1.9 5.1e-09 36.2 1.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM63772.1 - 1.2e-06 28.8 12.6 0.00014 22.4 5.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63772.1 - 1.9e-06 27.5 0.5 1.9e-06 27.5 0.5 2.7 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KFM63772.1 - 0.016 14.9 6.4 0.026 14.1 3.0 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 KFM63772.1 - 0.016 15.7 9.5 0.083 13.4 5.5 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KFM63772.1 - 0.12 12.8 7.3 0.31 11.5 3.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFM63772.1 - 0.41 11.0 7.4 0.71 10.2 2.4 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) LIM PF00412.22 KFM63772.1 - 0.48 10.7 10.2 2.8 8.2 0.9 2.1 1 1 1 2 2 2 0 LIM domain DUF1390 PF07150.11 KFM63772.1 - 2.3 7.9 6.1 3.7 7.2 6.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1390) zf-BED PF02892.15 KFM63772.1 - 7.2 6.7 13.2 0.46 10.6 5.3 2.3 1 1 1 2 2 2 0 BED zinc finger RAG2_PHD PF13341.6 KFM63773.1 - 0.042 13.9 2.9 0.056 13.5 2.9 1.2 1 0 0 1 1 1 0 RAG2 PHD domain zf-H2C2_2 PF13465.6 KFM63774.1 - 2.4e-14 53.0 10.0 7.8e-07 29.2 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63774.1 - 3.2e-12 46.2 14.1 1.3e-06 28.5 1.3 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63774.1 - 1.3e-08 35.0 14.0 0.00038 21.0 1.3 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63774.1 - 6.7e-08 32.1 10.5 4.3e-05 23.2 1.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFM63774.1 - 0.00018 21.8 14.4 0.0073 16.7 0.5 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM63774.1 - 0.00024 21.4 2.1 0.00024 21.4 2.1 2.1 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFM63774.1 - 0.00038 20.7 11.6 0.026 14.8 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 KFM63774.1 - 0.026 14.7 10.1 0.65 10.2 0.7 3.1 3 0 0 3 3 3 0 AN1-like Zinc finger zf-C2H2_2 PF12756.7 KFM63774.1 - 0.028 14.7 8.4 0.25 11.7 0.1 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-nanos PF05741.13 KFM63774.1 - 0.03 14.5 5.7 1.1 9.5 1.3 2.9 1 1 1 2 2 2 0 Nanos RNA binding domain Endonuclease_7 PF02945.15 KFM63774.1 - 0.08 12.9 4.5 0.098 12.6 0.8 2.0 1 1 1 2 2 2 0 Recombination endonuclease VII GAGA PF09237.11 KFM63774.1 - 0.14 12.0 1.1 0.28 11.0 0.0 2.0 1 1 1 2 2 2 0 GAGA factor HNH_5 PF14279.6 KFM63774.1 - 0.16 11.8 5.9 1 9.3 2.1 2.8 2 1 0 2 2 2 0 HNH endonuclease zf-CCHC_2 PF13696.6 KFM63774.1 - 0.47 10.3 0.5 0.47 10.3 0.5 3.0 3 0 0 3 3 3 0 Zinc knuckle zf-DBF PF07535.12 KFM63774.1 - 0.57 10.3 7.9 2.4 8.3 0.1 2.9 3 1 0 3 3 3 0 DBF zinc finger C1_2 PF03107.16 KFM63774.1 - 0.63 10.4 15.1 6.1 7.2 1.5 3.3 2 1 0 2 2 2 0 C1 domain zf-MYST PF17772.1 KFM63774.1 - 0.73 9.5 8.7 1.5 8.5 0.2 3.0 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2HE PF16278.5 KFM63774.1 - 0.98 9.9 8.3 1.7 9.1 0.0 2.5 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-UBP PF02148.19 KFM63774.1 - 1.1 9.7 8.9 10 6.6 8.9 2.2 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf_UBZ PF18439.1 KFM63774.1 - 1.8 8.3 8.7 4.4 7.0 0.3 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KFM63774.1 - 3.2 7.8 17.9 3.7 7.7 1.6 3.2 1 1 2 3 3 3 0 BED zinc finger zf_C2H2_ZHX PF18387.1 KFM63774.1 - 4.4 7.0 14.2 0.73 9.5 3.8 2.9 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain RVT_1 PF00078.27 KFM63775.1 - 2e-06 27.5 0.0 2.1e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 KFM63776.1 - 4e-10 39.7 7.0 1.2e-09 38.2 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM63776.1 - 5.1e-09 35.7 5.3 5.1e-09 35.7 5.3 1.7 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM63776.1 - 1.8e-08 34.4 10.2 0.001 19.4 0.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63776.1 - 1.1e-05 25.9 7.9 0.04 14.8 2.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 KFM63776.1 - 0.023 14.7 10.5 0.34 11.0 1.0 2.1 1 1 1 2 2 2 0 BED zinc finger zf-CHCC PF10276.9 KFM63776.1 - 0.061 13.4 2.9 5 7.3 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger domain AKAP95 PF04988.12 KFM63776.1 - 0.096 12.9 2.9 0.15 12.3 2.9 1.5 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFM63776.1 - 0.11 12.9 4.5 0.12 12.7 0.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 KFM63776.1 - 0.15 12.2 5.9 1.7 8.9 5.9 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger DUF1390 PF07150.11 KFM63776.1 - 0.16 11.6 3.4 0.15 11.7 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) zf-C2HE PF16278.5 KFM63776.1 - 0.19 12.2 2.7 1.5 9.3 0.4 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFM63776.1 - 0.25 11.4 0.4 0.25 11.4 0.4 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KFM63776.1 - 0.29 11.6 8.1 1.8 9.1 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KFM63776.1 - 0.35 10.5 5.0 0.28 10.9 3.2 1.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 KFM63778.1 - 5e-13 48.8 2.3 2e-07 31.1 1.0 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63778.1 - 2.8e-05 24.3 13.1 3e-05 24.2 3.9 2.5 3 0 0 3 3 2 1 Zinc finger, C2H2 type zf_UBZ PF18439.1 KFM63778.1 - 0.00096 18.7 1.0 0.21 11.2 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-CCHC_2 PF13696.6 KFM63778.1 - 0.002 17.9 4.0 0.41 10.5 0.3 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_4 PF13894.6 KFM63778.1 - 0.0027 18.4 8.1 0.0084 16.9 3.6 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM63778.1 - 0.0035 17.3 8.2 0.049 13.6 3.7 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFM63778.1 - 0.0049 17.0 0.5 0.011 15.9 0.5 1.6 1 1 0 1 1 1 1 Zinc ribbon domain C1_1 PF00130.22 KFM63778.1 - 0.0051 16.7 1.9 1.1 9.2 0.2 2.0 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_ZIC PF18366.1 KFM63778.1 - 0.006 16.7 0.7 0.0085 16.2 0.7 1.3 1 0 0 1 1 1 1 Zic proteins zinc finger domain zf-UBP PF02148.19 KFM63778.1 - 0.012 15.9 3.5 0.041 14.2 1.5 1.9 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DZR PF12773.7 KFM63778.1 - 0.013 15.5 0.7 0.016 15.2 0.7 1.2 1 0 0 1 1 1 0 Double zinc ribbon YhfH PF14149.6 KFM63778.1 - 0.023 14.7 0.1 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 YhfH-like protein zf-AN1 PF01428.16 KFM63778.1 - 0.027 14.6 5.3 0.05 13.8 1.4 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger DUF2256 PF10013.9 KFM63778.1 - 0.033 14.3 0.7 1.3 9.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Di19 PF05605.12 KFM63778.1 - 0.034 14.4 1.6 0.045 14.0 1.6 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 KFM63778.1 - 0.036 14.1 0.9 0.057 13.4 0.9 1.4 1 1 0 1 1 1 0 Adenylate kinase, active site lid DUF4428 PF14471.6 KFM63778.1 - 0.068 13.1 1.9 1.7 8.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-trcl PF13451.6 KFM63778.1 - 0.083 12.8 0.8 1.1 9.2 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain DUF4932 PF16286.5 KFM63778.1 - 0.11 11.8 0.1 0.11 11.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) zf-met PF12874.7 KFM63778.1 - 0.22 12.0 5.6 0.72 10.3 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ribosomal_L28 PF00830.19 KFM63778.1 - 0.87 9.8 3.9 2.9 8.1 0.3 2.1 2 0 0 2 2 2 0 Ribosomal L28 family zf-H2C2_2 PF13465.6 KFM63779.1 - 2.5e-16 59.3 5.4 1.9e-10 40.6 0.1 4.3 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63779.1 - 3.9e-12 45.9 31.5 3.7e-05 24.0 2.0 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63779.1 - 9.7e-11 41.6 28.3 0.00027 21.5 2.2 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63779.1 - 2.9e-07 30.1 7.9 2.9e-07 30.1 7.9 3.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM63779.1 - 2.5e-05 24.4 5.2 0.0014 18.9 1.4 3.5 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 KFM63779.1 - 0.0011 19.0 14.0 0.0012 19.0 1.7 3.2 2 1 1 3 3 3 2 AN1-like Zinc finger zf-met PF12874.7 KFM63779.1 - 0.0048 17.2 10.6 0.022 15.1 1.9 3.3 3 1 0 3 3 3 2 Zinc-finger of C2H2 type PHD PF00628.29 KFM63779.1 - 0.036 14.0 10.1 0.39 10.6 6.0 2.2 2 0 0 2 2 2 0 PHD-finger zf_UBZ PF18439.1 KFM63779.1 - 0.045 13.3 0.2 0.045 13.3 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 KFM63779.1 - 0.12 12.3 14.2 1.2 9.1 0.7 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_3rep PF18868.1 KFM63779.1 - 0.15 12.8 7.2 3 8.5 1.7 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KFM63779.1 - 0.15 12.4 15.7 0.75 10.2 0.7 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CCHC_2 PF13696.6 KFM63779.1 - 0.26 11.1 0.5 0.26 11.1 0.5 3.4 4 0 0 4 4 4 0 Zinc knuckle zf-MYST PF17772.1 KFM63779.1 - 0.29 10.8 13.4 0.39 10.4 0.1 3.0 3 0 0 3 3 3 0 MYST family zinc finger domain DUF2180 PF09947.9 KFM63779.1 - 0.57 10.2 8.8 0.055 13.4 2.2 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) Zn-ribbon_8 PF09723.10 KFM63779.1 - 7.4 6.8 13.2 2.2 8.5 2.2 3.4 2 2 2 4 4 4 0 Zinc ribbon domain PRA1 PF03208.19 KFM63780.1 - 0.016 14.8 0.3 0.017 14.7 0.3 1.1 1 0 0 1 1 1 0 PRA1 family protein SAM_1 PF00536.30 KFM63782.1 - 5.4e-15 55.6 0.0 1.2e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM63782.1 - 1.4e-14 53.9 0.1 3e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFM63782.1 - 1.8e-12 46.9 0.1 4.9e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM63782.1 - 7.7e-12 45.4 0.1 1.9e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM63782.1 - 0.031 14.6 0.1 0.088 13.1 0.1 1.7 1 0 0 1 1 1 0 PDZ domain Ank_2 PF12796.7 KFM63783.1 - 1e-21 77.3 3.1 7.8e-10 39.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM63783.1 - 2.8e-19 69.2 0.8 1.9e-08 34.7 0.1 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM63783.1 - 2e-17 63.0 1.8 2.9e-08 33.8 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM63783.1 - 1.9e-15 56.5 10.9 3.4e-05 24.1 0.0 5.3 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFM63783.1 - 3.1e-12 45.5 5.8 0.0019 18.5 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat FERM_f0 PF16511.5 KFM63783.1 - 6e-09 36.1 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM DDE_3 PF13358.6 KFM63784.1 - 0.0023 17.7 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PRE_C2HC PF07530.11 KFM63785.1 - 5.4e-06 26.4 0.1 1.5e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Associated with zinc fingers RNase_H PF00075.24 KFM63786.1 - 3.1e-09 37.2 0.1 4e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM63786.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.4 1 1 0 1 1 1 0 Reverse transcriptase-like HTH_Tnp_Tc3_2 PF01498.18 KFM63787.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63787.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63787.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63787.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63787.1 - 0.027 14.6 0.4 0.085 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM63787.1 - 2.1 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Dimer_Tnp_hAT PF05699.14 KFM63788.1 - 1.9e-20 72.4 0.1 4e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KFM63788.1 - 0.0056 16.7 0.2 0.013 15.5 0.2 1.6 1 0 0 1 1 1 1 BED zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM63789.1 - 3.1e-16 59.4 2.2 5.8e-16 58.5 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63789.1 - 1.4e-13 50.8 0.0 2.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63790.1 - 2.1e-16 59.9 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63790.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GDI PF00996.18 KFM63791.1 - 1e-59 202.2 0.2 1.3e-59 201.9 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor FKBP_C PF00254.28 KFM63793.1 - 3.8e-36 123.3 0.0 7e-36 122.4 0.0 1.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DDE_3 PF13358.6 KFM63795.1 - 4e-12 46.1 0.4 5.2e-09 36.0 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 KFM63797.1 - 6.2e-31 106.4 0.0 1.7e-30 105.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM63797.1 - 4e-28 98.5 1.3 7.5e-28 97.6 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM63797.1 - 5.1e-28 97.4 0.0 1.5e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM63797.1 - 7.4e-20 70.8 0.2 2.9e-19 68.9 0.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM63797.1 - 6.6e-18 65.0 0.0 1.7e-15 57.2 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KFM63797.1 - 2.9e-09 37.4 0.0 9.2e-09 35.8 0.0 1.9 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM63797.1 - 1.5e-05 25.6 0.0 3.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM63797.1 - 1.7e-05 25.0 0.0 4.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KFM63797.1 - 5.1e-05 23.4 1.0 0.00013 22.1 1.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KFM63797.1 - 8.2e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Arc_C PF18162.1 KFM63797.1 - 0.00016 21.5 3.1 0.00018 21.3 0.6 2.4 2 0 0 2 2 2 1 Arc C-lobe RVT_3 PF13456.6 KFM63797.1 - 0.0026 17.6 0.1 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Asp_protease PF09668.10 KFM63797.1 - 0.0033 17.2 0.1 0.0073 16.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease BH4 PF02180.17 KFM63797.1 - 0.059 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 Retrotrans_gag PF03732.17 KFM63797.1 - 0.1 12.9 0.0 9.3 6.6 0.0 3.6 4 0 0 4 4 4 0 Retrotransposon gag protein Peptidase_A17 PF05380.13 KFM63798.1 - 9.5e-35 120.0 0.1 1.3e-26 93.5 0.0 2.7 1 1 1 2 2 2 2 Pao retrotransposon peptidase DUF5641 PF18701.1 KFM63798.1 - 1.2e-17 63.8 0.7 3.8e-17 62.2 0.7 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5641) RVT_1 PF00078.27 KFM63798.1 - 0.0004 20.0 1.0 0.00061 19.4 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KFM63798.1 - 0.012 15.3 0.1 0.042 13.5 0.1 2.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DDE_1 PF03184.19 KFM63799.1 - 8.3e-12 45.1 0.0 2e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM63799.1 - 2.6e-11 43.4 0.1 5e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain BrkDBD PF09607.10 KFM63799.1 - 7.7e-08 32.0 0.2 2.6e-07 30.3 0.2 1.9 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_1 PF01527.20 KFM63799.1 - 0.0098 16.2 2.8 0.035 14.4 1.4 2.2 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 KFM63799.1 - 0.073 13.2 0.1 0.22 11.7 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 KFM63799.1 - 0.67 9.6 4.1 0.69 9.6 0.1 3.0 3 1 1 4 4 4 0 CENP-B N-terminal DNA-binding domain Pkinase PF00069.25 KFM63800.1 - 2e-76 256.9 0.0 2.6e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM63800.1 - 3.1e-37 128.3 0.0 4.5e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFM63800.1 - 4.2e-18 65.8 0.1 9.3e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 KFM63800.1 - 1.3e-09 38.6 4.7 2.9e-09 37.5 4.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFM63800.1 - 2.1e-09 37.1 0.0 3.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KFM63800.1 - 0.00072 19.2 0.3 0.38 10.3 0.1 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 PH_11 PF15413.6 KFM63800.1 - 0.065 13.7 1.4 1.6 9.2 1.4 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Haspin_kinase PF12330.8 KFM63800.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Rrp15p PF07890.12 KFM63801.1 - 1.3e-19 70.8 18.1 6e-19 68.7 17.9 2.0 1 1 1 2 2 2 1 Rrp15p CEBP1_N PF16368.5 KFM63801.1 - 0.013 15.0 1.5 0.055 13.0 0.3 2.1 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus DUF1644 PF07800.12 KFM63801.1 - 0.02 14.9 1.5 0.028 14.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Neurochondrin PF05536.11 KFM63802.1 - 5.6e-37 127.4 1.1 6.4e-37 127.2 1.1 1.0 1 0 0 1 1 1 1 Neurochondrin DUF4004 PF13171.6 KFM63802.1 - 0.11 12.7 0.8 0.52 10.5 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4004) Neurochondrin PF05536.11 KFM63803.1 - 4.6e-47 160.7 4.2 5.5e-47 160.5 4.2 1.1 1 0 0 1 1 1 1 Neurochondrin HSD3 PF15244.6 KFM63804.1 - 5.7e-13 49.2 12.3 3.3e-12 46.7 9.5 2.3 2 1 0 2 2 2 1 Spermatogenesis-associated protein 7, or HSD3 Bacillus_HBL PF05791.11 KFM63804.1 - 0.12 12.2 3.1 0.21 11.4 3.1 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) 7TMR-HDED PF07697.11 KFM63804.1 - 2 8.5 5.7 1.9 8.6 4.2 1.4 1 1 0 1 1 1 0 7TM-HD extracellular HSD3 PF15244.6 KFM63805.1 - 1.4e-07 31.4 1.5 1.6e-07 31.2 1.5 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated protein 7, or HSD3 DUF2439 PF10382.9 KFM63805.1 - 0.064 13.6 0.3 0.13 12.6 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2439) zf-CCCH PF00642.24 KFM63806.1 - 1.5e-10 40.7 26.4 3.7e-06 26.7 2.3 3.2 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFM63806.1 - 6.5e-06 26.3 10.3 0.00052 20.2 5.3 2.3 2 0 0 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 KFM63806.1 - 4.2e-05 23.5 28.6 0.0047 16.9 5.3 3.9 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 KFM63806.1 - 0.00014 22.2 27.0 0.0056 17.1 4.1 3.3 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KFM63806.1 - 0.0045 17.7 13.5 0.07 13.8 0.3 3.2 1 1 2 3 3 3 2 Torus domain bZIP_2 PF07716.15 KFM63806.1 - 0.017 15.2 3.0 0.033 14.3 0.9 2.4 1 1 1 2 2 2 0 Basic region leucine zipper TPR_MLP1_2 PF07926.12 KFM63806.1 - 0.018 15.1 0.5 0.036 14.1 0.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 KFM63806.1 - 0.018 14.9 0.4 0.036 13.9 0.4 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH NRBF2 PF08961.10 KFM63806.1 - 0.027 14.1 0.6 0.06 12.9 0.6 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TSC22 PF01166.18 KFM63806.1 - 0.044 14.1 3.0 0.058 13.7 0.8 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KFM63806.1 - 0.097 12.8 1.7 0.2 11.7 1.3 1.7 1 1 0 1 1 1 0 bZIP transcription factor zf-CCCH_4 PF18044.1 KFM63806.1 - 0.71 9.8 28.0 0.071 12.9 4.1 3.3 3 0 0 3 3 3 0 CCCH-type zinc finger ZapB PF06005.12 KFM63806.1 - 2.6 8.6 6.6 0.48 10.9 2.8 1.7 2 0 0 2 2 2 0 Cell division protein ZapB Spindle_Spc25 PF08234.12 KFM63807.1 - 1.9e-20 72.8 0.4 2.1e-20 72.7 0.4 1.1 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DNA_repr_REX1B PF14966.6 KFM63807.1 - 0.033 14.8 0.0 0.038 14.6 0.0 1.1 1 0 0 1 1 1 0 DNA repair REX1-B Lipoprotein_X PF03305.13 KFM63807.1 - 0.054 13.2 0.1 0.086 12.6 0.0 1.4 1 1 0 1 1 1 0 Mycoplasma MG185/MG260 protein Trypsin PF00089.26 KFM63809.1 - 1.8e-59 201.3 0.0 9.3e-59 198.9 0.0 2.2 2 0 0 2 2 2 1 Trypsin Trypsin PF00089.26 KFM63810.1 - 9.6e-28 97.5 0.0 2.3e-27 96.3 0.0 1.7 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM63810.1 - 0.009 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFM63811.1 - 1.7e-20 73.8 0.1 1.8e-20 73.7 0.1 1.0 1 0 0 1 1 1 1 Trypsin MRF_C1 PF13887.6 KFM63814.1 - 2.5e-22 77.7 2.2 2.5e-22 77.7 2.2 1.8 2 0 0 2 2 2 1 Myelin gene regulatory factor -C-terminal domain 1 Peptidase_S74 PF13884.6 KFM63814.1 - 2.2e-13 50.3 0.0 6.3e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Chaperone of endosialidase NDT80_PhoG PF05224.12 KFM63814.1 - 1.6e-07 31.7 0.0 3.9e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Cluap1 PF10234.9 KFM63814.1 - 0.2 11.0 2.1 0.14 11.5 0.3 1.6 2 0 0 2 2 2 0 Clusterin-associated protein-1 NDT80_PhoG PF05224.12 KFM63815.1 - 0.042 14.1 0.0 0.042 14.1 0.0 1.8 3 0 0 3 3 3 0 NDT80 / PhoG like DNA-binding family HTH_Tnp_Tc3_2 PF01498.18 KFM63816.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63816.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63816.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63816.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63816.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain EF-hand_1 PF00036.32 KFM63817.1 - 4.8e-43 141.5 10.8 5.9e-10 38.0 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFM63817.1 - 2.6e-36 123.9 2.7 1.6e-18 66.9 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFM63817.1 - 1.7e-33 114.3 11.2 8.6e-16 57.5 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFM63817.1 - 1.2e-30 102.7 6.0 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFM63817.1 - 1.5e-27 93.8 8.3 7.4e-07 28.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFM63817.1 - 7.7e-16 58.2 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFM63817.1 - 1.7e-10 40.7 0.4 4.2e-05 23.4 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFM63817.1 - 6.3e-08 32.9 0.0 0.0064 16.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KFM63817.1 - 1.3e-06 29.2 0.0 0.00052 20.8 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFM63817.1 - 1.4e-05 25.0 0.0 0.042 13.9 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFM63817.1 - 7.1e-05 22.8 0.7 0.0005 20.1 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KFM63817.1 - 0.00022 21.4 4.2 0.055 13.7 0.4 3.1 1 1 1 2 2 2 2 Dockerin type I domain DUF1103 PF06513.11 KFM63817.1 - 0.00048 19.8 1.9 0.00052 19.7 1.9 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 KFM63817.1 - 0.0011 19.7 0.4 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 KFM63817.1 - 0.0016 18.4 0.9 0.53 10.2 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KFM63817.1 - 0.0027 18.0 0.6 1.6 9.1 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 KFM63817.1 - 0.0028 18.1 0.0 1.4 9.4 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 KFM63817.1 - 0.0039 17.1 0.6 0.49 10.4 0.1 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF5580 PF17743.1 KFM63817.1 - 0.01 14.4 0.0 0.01 14.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Poly_export PF02563.16 KFM63817.1 - 0.013 15.8 0.0 0.95 9.7 0.0 3.0 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 KFM63817.1 - 0.015 15.2 0.6 0.9 9.4 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 KFM63817.1 - 0.021 15.0 0.4 0.38 10.9 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KFM63817.1 - 0.025 13.8 0.1 2.2 7.4 0.0 2.3 1 1 0 2 2 2 0 Cache domain DUF2267 PF10025.9 KFM63817.1 - 0.033 14.5 0.0 0.15 12.4 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Fe_hyd_lg_C PF02906.14 KFM63817.1 - 0.044 13.4 0.7 0.18 11.4 0.7 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 KFM63817.1 - 0.067 13.5 0.1 9.2 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain TetR_C_7 PF14246.6 KFM63817.1 - 0.081 13.0 0.1 7.8 6.6 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Spore_III_AB PF09548.10 KFM63817.1 - 0.12 12.5 0.3 0.24 11.5 0.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RuvA_C PF07499.13 KFM63817.1 - 0.14 12.6 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain CMD PF02627.20 KFM63817.1 - 0.17 12.0 0.3 7.3 6.7 0.0 2.8 3 1 0 3 3 3 0 Carboxymuconolactone decarboxylase family SapB_1 PF05184.15 KFM63817.1 - 0.23 11.5 1.2 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 Eapp_C PF10238.9 KFM63818.1 - 3.5e-44 150.5 20.5 9.3e-44 149.1 9.1 3.0 2 1 0 2 2 2 1 E2F-associated phosphoprotein IBR PF01485.21 KFM63818.1 - 0.012 15.9 1.2 0.82 9.9 0.1 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain WD40_3 PF15911.5 KFM63818.1 - 0.053 13.5 0.5 13 5.9 0.0 2.6 2 1 0 2 2 2 0 WD domain, G-beta repeat C1_4 PF07975.12 KFM63818.1 - 0.095 13.0 0.5 0.095 13.0 0.5 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain DUF678 PF05077.12 KFM63818.1 - 0.15 12.2 5.4 3.2 7.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Yippee-Mis18 PF03226.14 KFM63818.1 - 0.88 9.8 6.0 0.72 10.1 4.3 1.7 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ldh_1_N PF00056.23 KFM63819.1 - 5.5e-38 130.2 0.0 1.2e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFM63819.1 - 1.2e-37 129.4 0.0 2.1e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Arginase PF00491.21 KFM63821.1 - 6.3e-65 219.4 0.0 7.5e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family PARP PF00644.20 KFM63822.1 - 5.7e-73 244.7 0.6 5.7e-73 244.7 0.6 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KFM63822.1 - 2.1e-49 167.1 0.5 5.4e-49 165.8 0.5 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.18 KFM63822.1 - 3.2e-36 124.0 15.0 2.6e-19 69.9 0.3 3.1 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGR PF05406.15 KFM63822.1 - 1.5e-21 76.3 1.7 1.5e-21 76.3 1.7 2.4 2 0 0 2 2 2 1 WGR domain PADR1 PF08063.12 KFM63822.1 - 1e-19 70.0 1.6 1e-19 70.0 1.6 2.2 3 0 0 3 3 3 1 PADR1 (NUC008) domain BRCT PF00533.26 KFM63822.1 - 2.5e-06 27.8 0.0 1.2e-05 25.6 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFM63822.1 - 0.071 13.1 0.0 0.28 11.1 0.0 2.1 1 0 0 1 1 1 0 twin BRCT domain zf-PARP PF00645.18 KFM63823.1 - 2.6e-36 124.3 17.8 4.7e-19 69.0 4.5 3.5 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.12 KFM63823.1 - 5.2e-19 67.8 0.4 5.2e-19 67.8 0.4 2.5 2 0 0 2 2 2 1 PADR1 (NUC008) domain BRCT PF00533.26 KFM63823.1 - 0.0011 19.2 0.0 0.0047 17.3 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFM63823.1 - 0.013 15.9 1.4 0.046 14.1 0.0 2.5 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KFM63823.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain Sof1 PF04158.14 KFM63823.1 - 0.57 10.5 5.4 0.19 12.0 1.0 2.3 2 0 0 2 2 2 0 Sof1-like domain DDE_3 PF13358.6 KFM63824.1 - 3.4e-05 23.6 0.0 4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63825.1 - 5.6e-14 52.1 0.5 5.9e-14 52.1 0.5 1.0 1 0 0 1 1 1 1 Transposase FUR PF01475.19 KFM63825.1 - 0.083 13.0 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Ferric uptake regulator family 5_3_exonuc_N PF02739.16 KFM63826.1 - 1.1e-08 35.1 0.0 2.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain XPG_I_2 PF12813.7 KFM63826.1 - 4.5e-06 26.3 0.0 8.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 KFM63826.1 - 0.0012 19.2 0.0 0.0041 17.6 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KFM63826.1 - 0.014 15.7 0.1 0.032 14.6 0.1 1.7 1 0 0 1 1 1 0 XPG I-region DOG1 PF14144.6 KFM63827.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Seed dormancy control HTH_Tnp_Tc3_2 PF01498.18 KFM63829.1 - 9.4e-18 64.2 2.8 1.7e-17 63.5 2.8 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63829.1 - 2.5e-06 28.0 5.2 3.6e-05 24.3 0.8 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM63829.1 - 0.0025 17.8 0.3 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix MarR_2 PF12802.7 KFM63829.1 - 0.0026 17.6 0.3 0.68 9.9 0.0 2.5 2 0 0 2 2 2 1 MarR family PAX PF00292.18 KFM63829.1 - 0.0068 16.3 0.1 0.044 13.7 0.0 2.1 2 0 0 2 2 2 1 'Paired box' domain HTH_28 PF13518.6 KFM63829.1 - 0.016 15.3 2.1 0.059 13.5 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM63829.1 - 0.025 14.5 1.4 0.1 12.6 0.0 2.2 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 KFM63829.1 - 0.034 14.2 0.2 0.58 10.3 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_33 PF13592.6 KFM63829.1 - 0.04 13.6 0.3 0.086 12.5 0.3 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_26 PF13443.6 KFM63829.1 - 0.051 14.0 0.7 6 7.4 0.4 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 KFM63829.1 - 0.27 10.8 1.5 3.8 7.1 0.0 2.5 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 KFM63830.1 - 9.6e-15 54.6 1.1 1.7e-14 53.8 1.1 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63830.1 - 0.00034 21.2 5.9 0.0049 17.4 1.5 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_3 PF01381.22 KFM63830.1 - 0.0039 17.2 0.2 0.022 14.8 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix MarR_2 PF12802.7 KFM63830.1 - 0.048 13.5 0.1 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 KFM63830.1 - 0.085 12.4 0.3 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding RT_RNaseH_2 PF17919.1 KFM63831.1 - 5.6e-31 106.5 0.0 1.5e-30 105.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM63831.1 - 3.3e-28 98.7 1.3 6.6e-28 97.7 0.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM63831.1 - 4.4e-28 97.6 0.0 1.4e-27 96.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM63831.1 - 6.6e-20 71.0 0.2 2.6e-19 69.1 0.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM63831.1 - 5.3e-18 65.3 0.0 1.5e-15 57.4 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KFM63831.1 - 2.4e-09 37.6 0.0 8.3e-09 35.9 0.0 2.0 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM63831.1 - 1.3e-05 25.8 0.0 3.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM63831.1 - 1.5e-05 25.2 0.0 4.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KFM63831.1 - 4.5e-05 23.6 1.0 0.00011 22.3 1.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KFM63831.1 - 7.2e-05 22.6 0.0 0.0002 21.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_3 PF13456.6 KFM63831.1 - 0.0022 17.8 0.1 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Asp_protease PF09668.10 KFM63831.1 - 0.0029 17.4 0.1 0.0066 16.2 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease BH4 PF02180.17 KFM63831.1 - 0.054 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 BEN PF10523.9 KFM63831.1 - 0.15 12.4 0.5 3.4 8.0 0.0 3.2 2 0 0 2 2 2 0 BEN domain EGF PF00008.27 KFM63832.1 - 3.8e-50 167.8 163.9 4.3e-08 33.3 8.3 11.3 10 1 0 10 10 10 8 EGF-like domain hEGF PF12661.7 KFM63832.1 - 2.7e-25 88.1 147.5 2.1e-05 24.9 7.7 12.7 13 0 0 13 13 12 8 Human growth factor-like EGF DSL PF01414.19 KFM63832.1 - 1.3e-23 83.0 8.5 1.3e-23 83.0 8.5 9.0 4 2 5 9 9 7 2 Delta serrate ligand EGF_2 PF07974.13 KFM63832.1 - 1.5e-19 70.1 190.3 0.00058 20.2 9.9 11.5 11 0 0 11 11 11 9 EGF-like domain RIFIN PF02009.16 KFM63832.1 - 0.00046 20.2 0.0 0.00096 19.1 0.0 1.5 1 0 0 1 1 1 1 Rifin TMEM51 PF15345.6 KFM63832.1 - 0.0025 17.7 0.4 0.0036 17.2 0.4 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Peptidase_M56 PF05569.11 KFM63832.1 - 0.0075 15.5 0.4 0.011 14.9 0.4 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 TMEM154 PF15102.6 KFM63832.1 - 0.02 14.8 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family EGF_CA PF07645.15 KFM63832.1 - 0.025 14.8 146.0 0.029 14.6 13.4 10.8 3 3 7 10 10 9 0 Calcium-binding EGF domain EphA2_TM PF14575.6 KFM63832.1 - 0.045 14.6 0.1 0.1 13.5 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 KFM63832.1 - 0.046 14.0 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 KFM63832.1 - 0.054 13.1 0.6 0.094 12.3 0.6 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4834 PF16118.5 KFM63832.1 - 0.066 14.2 0.1 0.13 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF5385 PF17359.2 KFM63832.1 - 0.11 12.0 2.6 0.14 11.7 0.3 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5385) 7TM_GPCR_Srv PF10323.9 KFM63832.1 - 0.11 11.8 0.2 0.17 11.2 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv BatD PF13584.6 KFM63832.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF2207 PF09972.9 KFM63832.1 - 0.21 10.3 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Neur_chan_memb PF02932.16 KFM63832.1 - 0.78 9.8 4.8 0.1 12.6 0.7 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Fibrinogen_C PF00147.18 KFM63833.1 - 3.1e-71 239.7 12.4 4.3e-71 239.2 12.4 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Chitin_bind_4 PF00379.23 KFM63835.1 - 2.7e-08 34.2 6.9 3.8e-08 33.7 6.9 1.2 1 0 0 1 1 1 1 Insect cuticle protein BRO1 PF03097.18 KFM63836.1 - 5.1e-41 140.8 0.7 6.9e-41 140.3 0.7 1.1 1 0 0 1 1 1 1 BRO1-like domain PDZ PF00595.24 KFM63836.1 - 6.6e-13 48.8 0.2 1.2e-12 48.0 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM63836.1 - 1.5e-08 34.4 0.1 3.5e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM63836.1 - 0.0023 18.2 0.1 0.0042 17.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Phlebovirus_NSM PF07246.11 KFM63836.1 - 0.0094 15.4 0.0 0.068 12.5 0.0 1.9 2 0 0 2 2 2 1 Phlebovirus nonstructural protein NS-M BRO1 PF03097.18 KFM63837.1 - 1.4e-17 63.6 0.1 1.5e-17 63.5 0.1 1.0 1 0 0 1 1 1 1 BRO1-like domain TetR_C_4 PF08359.11 KFM63837.1 - 0.084 13.0 0.0 0.099 12.8 0.0 1.0 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region Homoserine_dh PF00742.19 KFM63837.1 - 0.18 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Homoserine dehydrogenase RVT_1 PF00078.27 KFM63839.1 - 4.2e-08 33.0 0.0 5e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 KFM63841.1 - 2.2e-99 321.8 87.6 4.2e-10 39.6 0.3 14.9 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63841.1 - 2.1e-66 216.9 110.0 2.2e-06 27.8 1.5 15.3 15 0 0 15 15 15 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63841.1 - 7.8e-56 181.9 104.8 0.00054 20.6 1.4 15.2 15 0 0 15 15 15 15 C2H2-type zinc finger zf-met PF12874.7 KFM63841.1 - 8.1e-38 127.7 91.0 0.00054 20.3 0.1 15.4 15 0 0 15 15 15 14 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM63841.1 - 1.1e-35 120.9 93.6 0.00021 21.2 0.2 15.9 15 1 0 15 15 15 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM63841.1 - 1.9e-20 72.6 70.1 0.035 14.4 0.1 14.9 15 0 0 15 15 14 9 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM63841.1 - 4.6e-10 39.1 81.5 0.0051 16.5 1.0 14.8 15 0 0 15 15 15 7 C2H2-type zinc-finger domain DUF4825 PF16107.5 KFM63841.1 - 2e-08 34.3 0.0 0.46 10.6 0.0 5.1 2 2 3 5 5 5 1 Domain of unknown function (DUF4825) BolA PF01722.18 KFM63841.1 - 3e-08 33.8 14.7 0.23 11.8 0.1 7.5 3 1 1 6 6 5 3 BolA-like protein zf-MYST PF17772.1 KFM63841.1 - 1.6e-06 27.6 56.5 0.28 10.8 0.0 12.5 6 3 7 13 13 13 4 MYST family zinc finger domain zf-C2H2_11 PF16622.5 KFM63841.1 - 5.9e-05 22.7 91.7 0.022 14.5 3.1 14.1 15 0 0 15 15 15 5 zinc-finger C2H2-type Baculo_IE-1 PF05290.11 KFM63841.1 - 0.0011 18.9 47.9 1.8 8.5 0.5 10.6 2 1 7 9 9 9 2 Baculovirus immediate-early protein (IE-0) GAGA PF09237.11 KFM63841.1 - 0.0013 18.5 13.2 0.46 10.3 0.3 6.4 6 1 1 7 7 7 2 GAGA factor zinc_ribbon_15 PF17032.5 KFM63841.1 - 0.0053 17.5 50.2 0.66 10.8 1.0 7.8 1 1 8 9 9 9 4 zinc-ribbon family Complex1_49kDa PF00346.19 KFM63841.1 - 0.0057 15.8 0.4 11 5.0 0.0 3.5 2 2 2 4 4 4 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit HTH_18 PF12833.7 KFM63841.1 - 0.0086 16.3 0.2 12 6.2 0.0 4.9 7 0 0 7 7 6 0 Helix-turn-helix domain Herpes_ORF11 PF04797.13 KFM63841.1 - 0.019 13.8 0.3 3.6 6.3 0.0 2.9 2 1 1 3 3 3 0 Herpesvirus dUTPase protein zf-C2H2_2 PF12756.7 KFM63841.1 - 0.052 13.9 82.2 7.7 6.9 9.3 13.3 1 1 11 12 12 12 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM63841.1 - 0.13 12.2 42.3 7.5 6.6 0.1 11.4 12 0 0 12 12 12 0 zinc-finger of a C2HC-type Ribosomal_S14 PF00253.21 KFM63841.1 - 0.18 11.6 0.1 0.18 11.6 0.1 3.9 4 0 0 4 4 3 0 Ribosomal protein S14p/S29e HTH_5 PF01022.20 KFM63841.1 - 1.1 9.2 7.6 4.6 7.2 0.1 4.5 5 0 0 5 5 5 0 Bacterial regulatory protein, arsR family Zf_RING PF16744.5 KFM63841.1 - 1.2 9.3 70.4 8.1 6.6 1.8 13.5 3 2 10 13 13 12 0 KIAA1045 RING finger FYVE PF01363.21 KFM63841.1 - 2 8.6 71.3 0.48 10.6 4.4 8.1 4 1 2 6 6 6 0 FYVE zinc finger SLAM PF06214.11 KFM63845.1 - 0.22 11.5 0.1 0.29 11.1 0.1 1.1 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein HTH_Tnp_Tc3_2 PF01498.18 KFM63846.1 - 2.7e-16 59.6 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63846.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63846.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63846.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63846.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63847.1 - 2.8e-16 59.5 3.5 5.8e-16 58.5 2.2 2.2 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM63847.1 - 1.3e-13 51.0 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63847.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63847.1 - 0.0027 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63847.1 - 2.3 8.9 15.6 0.12 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63848.1 - 4e-16 59.0 3.4 5.2e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63848.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63848.1 - 1.7e-07 30.8 1.2 6.6e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63848.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63848.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63849.1 - 2.7e-16 59.6 2.8 4.8e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63849.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63849.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63849.1 - 0.0025 17.5 0.6 0.0066 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63849.1 - 0.028 14.5 0.4 0.079 13.1 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM63849.1 - 3.3 8.4 11.6 0.12 13.0 2.2 3.0 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63850.1 - 3.9e-15 55.9 2.0 7.9e-15 54.9 2.0 1.5 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM63850.1 - 7.2e-07 29.2 2.8 2.3e-06 27.6 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63850.1 - 0.001 18.8 1.6 0.019 14.7 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KFM63850.1 - 0.0037 16.6 1.0 0.067 12.6 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 KFM63850.1 - 0.0095 16.5 2.9 0.0095 16.5 2.9 2.3 1 1 1 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM63850.1 - 0.019 14.6 0.0 0.063 12.9 0.0 1.9 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain PAX PF00292.18 KFM63850.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain DDE_3 PF13358.6 KFM63850.1 - 0.15 11.8 0.0 3.8 7.2 0.0 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63851.1 - 7.2e-16 58.2 2.2 7.2e-16 58.2 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63851.1 - 1.7e-13 50.5 0.0 3.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63851.1 - 3.8e-07 29.8 1.6 8.6e-07 28.6 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63851.1 - 0.0032 17.2 0.5 0.0093 15.7 0.5 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63851.1 - 3.9 8.2 15.6 0.15 12.6 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63852.1 - 3.8e-16 59.1 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63852.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63852.1 - 3.2e-07 30.0 1.6 7.6e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63852.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63852.1 - 0.028 14.5 0.4 0.098 12.8 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM63852.1 - 0.76 10.4 15.7 0.13 12.8 2.0 3.8 3 1 1 4 4 4 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM63853.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63853.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM63854.1 - 2.8e-16 59.6 0.1 3.1e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63854.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Tetraspanin PF00335.20 KFM63855.1 - 4.1e-52 177.2 18.0 4.6e-52 177.0 18.0 1.0 1 0 0 1 1 1 1 Tetraspanin family YfhO PF09586.10 KFM63855.1 - 0.00071 17.9 0.7 0.00092 17.6 0.7 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO AA_permease_2 PF13520.6 KFM63855.1 - 0.0021 16.9 8.6 0.0021 16.9 8.6 1.7 2 0 0 2 2 2 1 Amino acid permease OAD_gamma PF04277.13 KFM63855.1 - 0.2 12.3 0.1 0.2 12.3 0.1 2.5 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DUF3487 PF11990.8 KFM63855.1 - 5.5 6.9 13.0 1.3 9.0 0.3 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3487) HTH_Tnp_Tc3_2 PF01498.18 KFM63856.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63856.1 - 9e-14 51.5 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C4 PF00105.18 KFM63858.1 - 4.9e-31 107.0 17.3 6.7e-31 106.6 17.3 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFM63859.1 - 2.6e-09 37.0 0.5 2.8e-09 36.8 0.5 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Goodbye PF17109.5 KFM63859.1 - 0.058 13.8 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain IFNGR1 PF07140.11 KFM63859.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) Transposase_1 PF01359.18 KFM63860.1 - 3e-21 75.0 0.2 8.3e-21 73.6 0.2 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) Zip PF02535.22 KFM63860.1 - 3.8e-13 49.4 0.0 9.1e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 ZIP Zinc transporter HTH_48 PF17906.1 KFM63860.1 - 2.6e-08 33.8 0.0 1.2e-07 31.8 0.0 2.2 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM63860.1 - 1.3e-06 28.9 0.1 7.4e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.6 KFM63860.1 - 0.0005 19.8 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 KFM63860.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_48 PF17906.1 KFM63861.1 - 0.0094 16.0 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Phytochelatin PF05023.14 KFM63861.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.0 1 0 0 1 1 1 0 Phytochelatin synthase EF-hand_1 PF00036.32 KFM63862.1 - 6.6e-11 40.9 1.8 1.4e-05 24.3 0.9 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFM63862.1 - 2.8e-10 39.3 3.2 9e-06 25.2 0.9 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KFM63862.1 - 1.3e-08 35.2 0.2 0.00038 20.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFM63862.1 - 3.6e-08 33.1 3.9 0.00011 22.0 0.0 3.5 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFM63862.1 - 0.00068 19.0 1.2 0.00068 19.0 1.2 2.2 2 0 0 2 2 2 1 EF hand Syntaxin PF00804.25 KFM63862.1 - 0.0057 16.4 0.1 2.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Syntaxin Caleosin PF05042.13 KFM63862.1 - 0.013 15.4 0.0 0.046 13.6 0.0 1.8 2 0 0 2 2 2 0 Caleosin related protein DUF3741 PF12552.8 KFM63862.1 - 0.05 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) RR_TM4-6 PF06459.12 KFM63862.1 - 4.5 7.0 9.2 27 4.5 6.2 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ATG27 PF09451.10 KFM63863.1 - 0.19 11.6 0.6 0.18 11.6 0.6 1.0 1 0 0 1 1 1 0 Autophagy-related protein 27 TRIQK PF15168.6 KFM63863.1 - 0.3 11.0 1.2 0.28 11.1 1.2 1.1 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family zf-CCHC PF00098.23 KFM63864.1 - 0.0034 17.4 1.3 0.011 15.8 1.3 1.9 1 0 0 1 1 1 1 Zinc knuckle RNase_H PF00075.24 KFM63864.1 - 0.011 15.9 0.1 0.021 15.0 0.1 1.6 1 1 0 1 1 1 0 RNase H BTB PF00651.31 KFM63865.1 - 4.8e-23 81.5 0.4 4.8e-23 81.5 0.4 1.6 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM63865.1 - 0.042 14.0 0.2 0.39 10.8 0.1 2.3 1 1 1 2 2 2 0 BTB And C-terminal Kelch 7tm_1 PF00001.21 KFM63867.1 - 3e-74 249.7 12.7 4e-74 249.3 12.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM63867.1 - 4.6e-11 42.6 12.1 1.5e-10 40.9 12.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFM63867.1 - 2.6e-08 33.9 12.0 3.7e-06 26.9 5.9 2.3 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFM63867.1 - 1.2e-05 25.1 7.6 1.2e-05 25.1 7.6 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Orai-1 PF07856.12 KFM63867.1 - 0.11 12.2 2.3 0.31 10.7 2.3 1.7 1 0 0 1 1 1 0 Mediator of CRAC channel activity Git3 PF11710.8 KFM63867.1 - 9.4 5.9 13.4 0.63 9.8 8.2 1.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 DDE_3 PF13358.6 KFM63868.1 - 3.9e-16 59.1 0.1 6.4e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63868.1 - 7.8e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63868.1 - 0.0051 17.4 0.6 0.0051 17.4 0.6 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63868.1 - 0.013 15.2 0.1 0.63 9.9 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain DEAD PF00270.29 KFM63869.1 - 5.7e-06 26.2 0.0 5.7e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ca_bind_SSO6904 PF18249.1 KFM63871.1 - 0.018 15.4 6.7 0.7 10.3 2.5 2.4 2 1 0 2 2 2 0 Calcium binding protein SSO6904 GLE1 PF07817.13 KFM63871.1 - 0.055 12.7 1.0 0.061 12.5 1.0 1.1 1 0 0 1 1 1 0 GLE1-like protein EAL PF00563.20 KFM63871.1 - 0.06 12.9 0.8 0.062 12.8 0.8 1.0 1 0 0 1 1 1 0 EAL domain LEM PF03020.15 KFM63872.1 - 6e-17 60.9 0.0 1.3e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 LEM domain HECT_2 PF09814.9 KFM63873.1 - 2.6e-11 43.0 2.6 3.2e-11 42.7 2.6 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-H2C2_2 PF13465.6 KFM63874.1 - 1.6e-36 123.1 41.2 2.2e-08 34.2 1.0 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63874.1 - 4.3e-29 99.3 45.0 9.6e-06 25.8 0.5 7.5 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63874.1 - 1.5e-17 62.7 41.6 0.0014 19.3 0.4 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFM63874.1 - 2.8e-06 27.5 15.6 0.0063 16.8 2.2 3.4 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFM63874.1 - 8.4e-06 25.9 11.5 0.12 12.7 0.2 5.8 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFM63874.1 - 2.2e-05 24.7 27.8 0.18 11.9 0.3 6.0 2 2 3 5 5 5 4 Aberrant zinc-finger zf-TRAF PF02176.18 KFM63874.1 - 0.0015 19.2 1.3 0.0015 19.2 1.3 3.7 2 1 2 4 4 4 1 TRAF-type zinc finger zf-MYST PF17772.1 KFM63874.1 - 0.44 10.2 4.1 0.34 10.6 1.3 2.2 2 0 0 2 2 2 0 MYST family zinc finger domain CHORD PF04968.12 KFM63874.1 - 0.84 10.4 22.8 1.6 9.5 0.6 5.4 1 1 4 5 5 5 0 CHORD zf-C2H2_6 PF13912.6 KFM63874.1 - 0.86 9.7 32.1 0.44 10.6 0.3 6.6 7 0 0 7 7 7 0 C2H2-type zinc finger DDE_3 PF13358.6 KFM63875.1 - 3.4e-08 33.4 0.0 4.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63877.1 - 1.1e-17 64.0 1.4 2e-17 63.2 1.4 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63877.1 - 1.2e-06 29.1 6.4 5.4e-06 26.9 1.7 2.4 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.6 KFM63877.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.6 KFM63879.1 - 2e-07 30.9 0.0 2.3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease ASC PF00858.24 KFM63880.1 - 6.9e-05 22.0 0.1 8.5e-05 21.7 0.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DDE_3 PF13358.6 KFM63882.1 - 0.00031 20.5 0.0 0.00046 19.9 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF668 PF05003.12 KFM63882.1 - 0.16 12.4 0.0 0.37 11.3 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF668) Frag1 PF10277.9 KFM63883.1 - 1.2e-05 24.9 0.4 1.5e-05 24.7 0.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SPC12 PF06645.13 KFM63883.1 - 0.1 12.7 1.2 0.17 12.0 0.2 1.7 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Frag1 PF10277.9 KFM63885.1 - 1.2e-21 77.3 18.0 1.8e-21 76.7 18.0 1.3 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family VESA1_N PF12785.7 KFM63885.1 - 0.048 12.6 0.4 0.068 12.1 0.4 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 DctQ PF04290.12 KFM63885.1 - 0.8 9.6 12.0 0.018 15.0 3.2 2.5 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component TMEM138 PF14935.6 KFM63885.1 - 5.6 7.7 13.5 0.09 13.4 3.7 2.5 3 0 0 3 3 3 0 Transmembrane protein 138 UPF0640 PF15114.6 KFM63886.1 - 6.8e-26 89.8 2.6 7.5e-26 89.7 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 Prefoldin_2 PF01920.20 KFM63887.1 - 2e-20 72.7 8.5 2.3e-20 72.5 8.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.9 KFM63887.1 - 0.00073 19.6 9.9 0.0026 17.8 2.0 2.1 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 KFM63887.1 - 0.011 15.6 3.5 0.018 14.9 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Herpes_UL6 PF01763.16 KFM63887.1 - 0.013 14.0 1.2 0.013 14.0 1.2 1.7 1 1 1 2 2 2 0 Herpesvirus UL6 like Mce4_CUP1 PF11887.8 KFM63887.1 - 0.039 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Snapin_Pallidin PF14712.6 KFM63887.1 - 0.044 14.2 10.7 0.18 12.2 1.4 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Alpha-2-MRAP_C PF06401.11 KFM63887.1 - 0.046 13.7 6.4 0.15 12.0 6.4 1.7 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain KELK PF15796.5 KFM63887.1 - 0.079 13.4 8.2 0.53 10.8 0.8 2.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spc7 PF08317.11 KFM63887.1 - 0.19 10.5 10.2 0.22 10.4 1.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Imm7 PF15585.6 KFM63887.1 - 0.2 11.9 1.9 11 6.3 0.1 2.0 1 1 1 2 2 2 0 Immunity protein 7 Phage_GP20 PF06810.11 KFM63887.1 - 0.21 11.4 11.3 0.4 10.5 2.8 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 ATG16 PF08614.11 KFM63887.1 - 0.21 11.8 13.2 0.081 13.1 2.8 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 KFM63887.1 - 0.36 10.9 12.3 1.6 8.8 2.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fzo_mitofusin PF04799.13 KFM63887.1 - 0.37 10.3 9.4 0.13 11.8 2.3 2.1 1 1 0 2 2 2 0 fzo-like conserved region SLIDE PF09111.10 KFM63887.1 - 0.5 10.4 4.9 0.4 10.7 1.8 2.0 2 0 0 2 2 2 0 SLIDE TMPIT PF07851.13 KFM63887.1 - 1.6 7.9 6.8 2.7 7.1 6.4 1.5 1 1 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 KFM63887.1 - 2.2 8.8 12.2 1.3 9.5 2.0 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Sec8_exocyst PF04048.14 KFM63887.1 - 3.2 7.6 11.3 1.1 9.1 2.7 2.5 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain TMF_DNA_bd PF12329.8 KFM63887.1 - 5.4 7.1 16.7 4.4 7.4 5.4 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 KFM63887.1 - 5.8 7.2 8.9 1.8 8.8 1.5 2.5 2 1 0 2 2 2 0 Haemolysin XhlA PhzC-PhzF PF02567.16 KFM63890.1 - 4.6e-50 170.7 0.0 5.9e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein HLH PF00010.26 KFM63891.1 - 2.4e-13 49.8 0.7 5.4e-13 48.7 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM63892.1 - 2.4e-14 53.3 0.6 4.7e-14 52.4 0.6 1.4 1 0 0 1 1 1 1 Transposase HTH_Crp_2 PF13545.6 KFM63892.1 - 3.7e-05 23.6 1.1 0.044 13.8 0.0 2.4 1 1 1 2 2 2 2 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM63892.1 - 0.00018 21.5 1.0 0.1 12.8 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 KFM63892.1 - 0.00026 20.8 0.4 0.087 12.7 0.0 2.5 2 0 0 2 2 2 2 MarR family HTH_3 PF01381.22 KFM63892.1 - 0.0011 19.0 0.7 0.17 11.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_32 PF13565.6 KFM63892.1 - 0.0027 18.3 5.5 0.012 16.3 2.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63892.1 - 0.0033 17.2 1.7 0.4 10.5 0.0 2.8 2 1 0 2 2 2 1 Homeodomain-like domain PAX PF00292.18 KFM63892.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 0 'Paired box' domain HTH_24 PF13412.6 KFM63892.1 - 0.02 14.4 0.2 6 6.5 0.2 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DDE_3 PF13358.6 KFM63893.1 - 1.8e-15 57.0 0.0 3.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63893.1 - 1.3e-10 41.4 1.0 2.7e-10 40.3 1.0 1.6 1 0 0 1 1 1 1 Transposase Noggin PF05806.12 KFM63895.1 - 8.8e-07 29.1 3.5 1e-06 28.8 3.5 1.1 1 0 0 1 1 1 1 Noggin Tox-URI2 PF15653.6 KFM63895.1 - 0.093 13.0 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 URI fold toxin 2 HTH_Tnp_Tc3_2 PF01498.18 KFM63897.1 - 5.2e-16 58.7 3.5 6.2e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63897.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63897.1 - 3.1e-07 30.0 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63897.1 - 0.003 17.3 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM63897.1 - 2.9 8.6 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 KFM63898.1 - 8e-12 45.0 5.5 5.3e-09 36.1 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63898.1 - 1.2e-08 34.9 8.8 0.00042 20.6 0.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63898.1 - 1.8e-06 28.3 10.3 0.0014 19.3 1.1 2.7 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63898.1 - 8.4e-06 25.4 0.3 8.4e-06 25.4 0.3 2.5 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-LITAF-like PF10601.9 KFM63898.1 - 0.00044 20.4 4.7 0.0031 17.8 0.2 2.4 2 1 0 2 2 2 1 LITAF-like zinc ribbon domain zf-Di19 PF05605.12 KFM63898.1 - 0.00095 19.4 5.8 0.0037 17.5 3.5 2.6 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFM63898.1 - 0.0083 16.4 1.7 0.0091 16.3 1.7 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf_C2H2_10 PF18414.1 KFM63898.1 - 0.01 15.4 3.4 0.014 15.0 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-C2H2_2 PF12756.7 KFM63898.1 - 0.015 15.6 4.5 0.19 12.1 0.7 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.15 KFM63898.1 - 0.016 15.3 4.5 0.09 12.8 2.3 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Prok-RING_4 PF14447.6 KFM63898.1 - 0.019 14.8 1.9 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 GAGA PF09237.11 KFM63898.1 - 0.023 14.5 4.6 0.13 12.1 0.1 2.7 1 1 2 3 3 3 0 GAGA factor zf-ribbon_3 PF13248.6 KFM63898.1 - 0.027 13.9 2.4 1.7 8.2 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFM63898.1 - 0.031 14.4 2.8 1.4 9.1 0.3 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_L37ae PF01780.19 KFM63898.1 - 0.055 13.5 5.2 0.75 9.9 0.2 2.7 1 1 2 3 3 3 0 Ribosomal L37ae protein family zf-met PF12874.7 KFM63898.1 - 0.076 13.4 6.2 1 9.9 0.6 2.7 2 1 1 3 3 3 0 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 KFM63898.1 - 0.087 12.8 4.3 0.45 10.5 4.3 2.1 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KFM63898.1 - 0.1 12.6 7.7 0.46 10.5 2.4 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TackOD1 PF18551.1 KFM63898.1 - 0.2 11.3 5.4 2.3 7.9 5.4 2.0 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 zf-C2H2_9 PF16293.5 KFM63898.1 - 0.2 11.5 4.6 6.8 6.6 0.1 2.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KFM63898.1 - 0.21 11.2 2.9 0.27 10.9 0.2 2.3 2 1 1 3 3 3 0 MYST family zinc finger domain CpXC PF14353.6 KFM63898.1 - 0.28 11.2 2.4 5.2 7.1 0.1 2.1 1 1 1 2 2 2 0 CpXC protein zinc_ribbon_9 PF14369.6 KFM63898.1 - 0.49 10.7 0.1 0.49 10.7 0.1 3.2 4 0 0 4 4 4 0 zinc-ribbon Ogr_Delta PF04606.12 KFM63898.1 - 0.51 10.4 4.6 8.3 6.5 0.7 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger FYDLN_acid PF09538.10 KFM63898.1 - 0.51 11.0 2.1 1.4 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) MFS_1 PF07690.16 KFM63899.1 - 4.3e-33 114.7 36.4 7.4e-31 107.4 30.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.20 KFM63899.1 - 5.9 6.6 13.4 0.17 11.6 0.3 3.4 3 1 0 3 3 3 0 Cyclin M transmembrane N-terminal domain zf-C2H2_9 PF16293.5 KFM63901.1 - 0.0099 15.7 0.3 0.018 14.9 0.3 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 KFM63902.1 - 8e-49 162.0 89.1 4.4e-08 33.2 0.4 12.0 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63902.1 - 2.3e-35 119.1 98.9 0.00017 21.8 0.4 11.6 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM63902.1 - 3e-25 86.7 89.1 0.0051 17.5 0.7 11.6 12 0 0 12 12 12 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM63902.1 - 1.4e-14 53.5 78.9 3.3e-06 26.7 4.1 10.5 11 0 0 11 11 11 6 C2H2-type zinc-finger domain BolA PF01722.18 KFM63902.1 - 0.0011 19.2 4.2 0.32 11.3 0.2 3.2 3 0 0 3 3 3 2 BolA-like protein zf-met PF12874.7 KFM63902.1 - 0.0015 18.9 46.8 0.046 14.1 0.3 9.2 9 1 0 9 9 9 3 Zinc-finger of C2H2 type GAGA PF09237.11 KFM63902.1 - 0.0049 16.7 26.1 0.33 10.8 0.6 6.7 4 3 2 6 6 6 3 GAGA factor zf-C2H2_jaz PF12171.8 KFM63902.1 - 0.0066 16.7 0.1 0.0066 16.7 0.1 9.9 11 0 0 11 11 11 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFM63902.1 - 8.8 6.9 55.5 0.15 12.5 0.4 9.0 4 3 4 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3512 PF12024.8 KFM63903.1 - 2.2e-69 233.6 1.8 3.7e-69 232.8 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 KFM63904.1 - 3.1e-25 88.0 0.3 6.2e-25 87.1 0.3 1.5 1 0 0 1 1 1 1 Bromodomain CDC45 PF02724.14 KFM63904.1 - 0.076 11.3 12.4 0.11 10.8 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KFM63904.1 - 0.13 11.0 6.8 0.16 10.7 6.8 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KFM63904.1 - 0.19 10.9 11.1 0.28 10.3 11.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_11 PF13086.6 KFM63904.1 - 1.2 8.8 10.7 1.8 8.3 10.7 1.4 1 0 0 1 1 1 0 AAA domain Dsh_C PF12316.8 KFM63904.1 - 1.9 8.8 7.4 2.9 8.3 7.4 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Endostatin PF06482.11 KFM63904.1 - 3.6 7.0 9.1 5.2 6.5 9.1 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF5427 PF10310.9 KFM63904.1 - 4.2 6.2 17.3 5.8 5.8 17.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Sec62 PF03839.16 KFM63904.1 - 5.5 6.4 17.2 0.19 11.2 10.5 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 ALMT PF11744.8 KFM63904.1 - 5.9 5.6 9.4 9 5.0 9.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM76 PF16046.5 KFM63904.1 - 7.5 5.8 20.4 0.37 10.1 14.8 1.7 2 0 0 2 2 2 0 FAM76 protein EOS1 PF12326.8 KFM63904.1 - 9.2 6.2 6.2 17 5.3 6.2 1.6 1 0 0 1 1 1 0 N-glycosylation protein SCHIP-1 PF10148.9 KFM63905.1 - 0.21 11.2 1.2 0.62 9.6 1.2 1.7 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 WD40 PF00400.32 KFM63908.1 - 0.27 12.2 0.1 0.27 12.2 0.1 3.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Sterol-sensing PF12349.8 KFM63910.1 - 2.9e-30 105.1 2.6 3.3e-30 104.9 2.6 1.0 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFM63910.1 - 5.1e-11 41.4 0.1 5.5e-11 41.3 0.1 1.0 1 0 0 1 1 1 1 Patched family EI24 PF07264.11 KFM63910.1 - 0.025 14.8 1.1 0.029 14.6 1.1 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) SDH_sah PF01972.16 KFM63910.1 - 0.29 10.1 0.9 0.33 9.9 0.3 1.4 1 1 1 2 2 2 0 Serine dehydrogenase proteinase Exo_endo_phos PF03372.23 KFM63913.1 - 0.0035 16.9 0.0 0.0035 16.9 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFM63914.1 - 1.4e-09 37.8 0.0 1.5e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DDE_Tnp_1_7 PF13843.6 KFM63915.1 - 0.0028 17.0 0.0 0.0032 16.8 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_IS1595 PF12762.7 KFM63916.1 - 1.2e-18 67.6 0.0 1.7e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.6 KFM63916.1 - 0.039 13.7 0.0 0.76 9.5 0.0 2.3 1 1 0 1 1 1 0 DDE superfamily endonuclease Zn_ribbon_recom PF13408.6 KFM63916.1 - 0.42 11.2 3.8 0.9 10.1 3.8 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DDE_3 PF13358.6 KFM63917.1 - 1e-11 44.8 1.9 1.8e-09 37.5 0.2 3.4 3 1 0 3 3 3 2 DDE superfamily endonuclease LRR_8 PF13855.6 KFM63919.1 - 2.7e-20 71.9 7.6 4.5e-09 35.9 0.1 4.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFM63919.1 - 3.4e-12 46.4 9.8 2.3e-06 27.8 0.1 4.1 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM63919.1 - 3.3e-09 36.8 0.1 5.8e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM63919.1 - 2.5e-05 23.8 2.9 0.00047 19.7 0.6 2.8 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 KFM63919.1 - 0.00022 21.4 11.9 29 5.8 0.0 7.8 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 KFM63919.1 - 0.00097 19.0 1.2 11 6.4 0.0 5.4 6 0 0 6 6 6 1 Leucine Rich repeat DUF3557 PF12078.8 KFM63919.1 - 0.091 12.7 3.7 1.1 9.2 0.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3557) LRR_8 PF13855.6 KFM63920.1 - 3.1e-20 71.7 4.4 1.3e-14 53.7 0.1 4.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFM63920.1 - 5.4e-08 33.0 0.9 0.00013 22.3 0.0 4.0 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM63920.1 - 0.0037 17.6 2.5 7.6 7.5 0.0 5.1 4 2 0 4 4 4 1 Leucine Rich Repeat LRRCT PF01463.24 KFM63920.1 - 0.037 14.6 0.2 0.1 13.2 0.2 1.8 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain TMEM171 PF15471.6 KFM63923.1 - 0.0015 17.6 0.0 0.0017 17.4 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein family 171 DUF973 PF06157.11 KFM63923.1 - 0.0081 15.2 0.3 0.01 14.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) DUF3185 PF11381.8 KFM63923.1 - 0.012 15.6 6.0 0.047 13.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF2207 PF09972.9 KFM63923.1 - 0.012 14.4 0.2 0.014 14.2 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) YtpI PF14007.6 KFM63923.1 - 0.028 14.5 1.9 0.036 14.2 1.5 1.4 1 1 0 1 1 1 0 YtpI-like protein PIRT PF15099.6 KFM63923.1 - 0.035 13.7 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3180 PF11377.8 KFM63923.1 - 0.054 13.6 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) DUF3784 PF12650.7 KFM63923.1 - 0.096 12.9 2.9 0.093 12.9 1.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) Phage_holin_3_6 PF07332.11 KFM63923.1 - 0.15 12.1 2.9 0.21 11.6 2.8 1.4 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ATP1G1_PLM_MAT8 PF02038.16 KFM63923.1 - 0.55 9.7 4.2 8.5 5.9 0.0 2.4 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family YrhK PF14145.6 KFM63923.1 - 0.61 10.0 5.8 1.8 8.5 6.1 1.6 1 1 0 1 1 1 0 YrhK-like protein DUF2157 PF09925.9 KFM63923.1 - 0.78 9.5 6.2 18 5.1 5.2 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Neurensin PF14927.6 KFM63923.1 - 2.4 7.9 5.8 7.6 6.2 0.3 2.1 1 1 1 2 2 2 0 Neurensin Pkinase PF00069.25 KFM63925.1 - 1.5e-14 54.0 0.2 3.3e-14 52.9 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFM63925.1 - 4.5e-14 52.3 0.0 4e-13 49.2 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain fn3 PF00041.21 KFM63925.1 - 6.9e-13 48.8 0.1 3e-12 46.7 0.1 2.2 1 0 0 1 1 1 1 Fibronectin type III domain Ig_3 PF13927.6 KFM63925.1 - 4.1e-09 36.9 6.8 4.8e-09 36.7 0.0 4.0 5 1 0 5 5 5 1 Immunoglobulin domain Pkinase_Tyr PF07714.17 KFM63925.1 - 4.7e-08 32.6 0.2 9e-08 31.7 0.2 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ig PF00047.25 KFM63925.1 - 6.5e-05 23.0 0.0 0.0003 20.9 0.0 2.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM63925.1 - 0.00014 22.1 0.2 0.0011 19.3 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 KFM63925.1 - 0.0017 18.5 0.0 0.23 11.7 0.0 3.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFM63925.1 - 7.2 7.3 9.2 1 10.0 0.0 3.9 3 2 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM63926.1 - 2.1e-16 59.9 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63926.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_1 PF00001.21 KFM63927.1 - 8.9e-07 28.5 0.6 9.4e-07 28.4 0.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.16 KFM63930.1 - 1.7e-25 89.7 20.1 2.7e-15 56.2 7.6 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFM63930.1 - 2.9e-13 49.2 14.5 1.2e-06 27.4 5.0 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFM63930.1 - 2.8e-06 26.5 17.6 6.2e-06 25.3 15.8 2.3 1 1 1 2 2 2 1 MFS_1 like family DUF3084 PF11283.8 KFM63930.1 - 0.12 12.3 0.5 3 7.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3084) HTH_Tnp_Tc3_2 PF01498.18 KFM63931.1 - 1.9e-31 108.1 16.3 1.6e-15 57.1 2.2 2.7 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM63931.1 - 1.4e-30 106.0 0.0 1.9e-14 53.6 0.0 3.2 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_38 PF13936.6 KFM63931.1 - 6.8e-08 32.2 4.0 1.7e-06 27.7 0.2 3.9 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM63931.1 - 1.3e-07 31.2 2.0 0.018 14.8 0.5 3.9 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 KFM63931.1 - 1.4e-05 25.2 3.1 0.1 12.7 0.1 3.1 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM63931.1 - 0.00012 21.8 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 Tc3 transposase HTH_32 PF13565.6 KFM63931.1 - 0.0018 18.9 1.5 0.0018 18.9 1.5 4.8 4 1 1 5 5 5 2 Homeodomain-like domain HTH_7 PF02796.15 KFM63931.1 - 0.0058 16.7 0.1 0.73 10.0 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM63931.1 - 0.011 15.7 6.3 0.071 13.1 0.2 3.2 3 0 0 3 3 3 0 Winged helix-turn helix PDZ PF00595.24 KFM63932.1 - 4e-49 164.9 0.1 9.3e-18 64.4 0.0 3.4 3 0 0 3 3 3 3 PDZ domain LRR_8 PF13855.6 KFM63932.1 - 8e-36 121.6 37.0 1.9e-07 30.7 2.3 7.7 2 2 7 9 9 9 9 Leucine rich repeat PDZ_6 PF17820.1 KFM63932.1 - 1.4e-24 85.7 0.1 4.3e-08 32.9 0.1 3.5 3 0 0 3 3 3 3 PDZ domain LRR_4 PF12799.7 KFM63932.1 - 3.7e-23 81.2 56.8 3.4e-05 24.1 1.5 9.5 2 2 10 13 13 13 11 Leucine Rich repeats (2 copies) PDZ_2 PF13180.6 KFM63932.1 - 6.2e-21 74.5 0.2 2e-09 37.7 0.1 3.6 3 0 0 3 3 3 3 PDZ domain CHASE5 PF17149.4 KFM63932.1 - 0.018 15.0 0.9 0.048 13.6 0.1 2.1 2 0 0 2 2 2 0 Periplasmic sensor domain found in signal transduction proteins LRR_5 PF13306.6 KFM63932.1 - 0.024 14.6 0.8 0.59 10.1 0.1 3.4 1 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) DUF5006 PF16397.5 KFM63932.1 - 0.048 12.8 0.2 0.12 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) RsmF_methylt_CI PF17126.5 KFM63932.1 - 0.23 11.5 2.3 54 3.9 0.0 4.7 6 0 0 6 6 6 0 RsmF rRNA methyltransferase first C-terminal domain Frizzled PF01534.17 KFM63933.1 - 5.5e-136 452.9 11.3 7.8e-136 452.4 11.3 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFM63933.1 - 3.4e-33 114.6 1.6 6e-33 113.8 0.6 1.9 2 0 0 2 2 2 1 Fz domain HgmA PF04209.13 KFM63935.1 - 4.1e-74 249.8 0.0 4.6e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase ANAPC4_WD40 PF12894.7 KFM63936.1 - 3.9e-06 27.1 0.0 0.011 16.0 0.0 2.9 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 KFM63936.1 - 0.028 13.7 0.3 7.4 5.8 0.0 2.4 1 1 0 2 2 2 0 CPSF A subunit region Utp8 PF10395.9 KFM63936.1 - 0.1 11.1 0.6 4.4 5.7 0.0 2.0 1 1 0 2 2 2 0 Utp8 family DUF2415 PF10313.9 KFM63936.1 - 0.12 12.4 0.0 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 KFM63936.1 - 0.16 12.9 5.5 0.25 12.3 0.0 3.5 3 1 1 4 4 4 0 WD domain, G-beta repeat FOXP-CC PF16159.5 KFM63938.1 - 0.00057 20.5 1.6 0.0029 18.2 1.6 2.3 1 1 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 KFM63938.1 - 0.0053 17.1 9.8 0.092 13.2 0.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM63938.1 - 0.04 14.4 0.7 0.04 14.4 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Ribosomal_S30 PF04758.14 KFM63940.1 - 1.3e-27 95.7 12.9 1.7e-27 95.4 12.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.23 KFM63940.1 - 1.5e-12 47.1 0.0 2.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFM63940.1 - 3.8e-05 23.4 0.0 6.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFM63940.1 - 0.013 16.0 0.1 0.02 15.4 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MBD PF01429.19 KFM63941.1 - 1.3e-52 175.4 0.1 4.8e-19 67.8 0.0 3.6 3 0 0 3 3 3 3 Methyl-CpG binding domain Clr2_transil PF16761.5 KFM63941.1 - 0.0001 23.0 0.0 8 7.4 0.0 3.6 3 0 0 3 3 3 2 Transcription-silencing protein, cryptic loci regulator Clr2 PET117 PF15786.5 KFM63941.1 - 0.15 12.3 3.4 0.75 10.1 3.4 2.2 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial DUF1041 PF06292.17 KFM63942.1 - 4.8e-34 116.9 6.3 4.8e-34 116.9 6.3 2.4 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1041) PH PF00169.29 KFM63942.1 - 8.1e-08 32.7 0.1 1.9e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 PH domain TERB2 PF15101.6 KFM63942.1 - 0.11 12.6 2.1 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 SUIM_assoc PF16619.5 KFM63942.1 - 0.2 11.8 6.9 0.75 9.9 6.9 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 VCBS PF13517.6 KFM63943.1 - 6.6e-20 71.5 2.3 7.3e-05 23.3 0.1 5.5 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFM63943.1 - 3.7e-09 36.5 5.1 0.14 12.3 0.0 5.5 6 0 0 6 6 6 5 FG-GAP repeat PHD PF00628.29 KFM63944.1 - 5.1e-08 32.7 11.3 5.1e-08 32.7 11.3 2.4 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFM63944.1 - 0.0026 17.3 6.6 0.009 15.5 6.6 2.0 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 KFM63944.1 - 0.015 15.7 11.4 0.011 16.1 6.5 3.2 2 1 0 2 2 2 0 SET domain YAF2_RYBP PF17219.3 KFM63945.1 - 2.3e-21 75.1 0.8 4.7e-21 74.1 0.8 1.6 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.18 KFM63945.1 - 1.9e-08 33.5 2.7 3.4e-08 32.6 2.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Ephrin_rec_like PF07699.13 KFM63945.1 - 0.069 12.9 0.7 0.069 12.9 0.7 2.0 2 0 0 2 2 2 0 Putative ephrin-receptor like YusW PF14039.6 KFM63945.1 - 0.089 13.3 0.3 0.15 12.5 0.3 1.4 1 0 0 1 1 1 0 YusW-like protein RP-C_C PF11800.8 KFM63945.1 - 4.9 7.2 10.0 0.44 10.6 1.1 2.1 1 1 1 2 2 2 0 Replication protein C C-terminal region Dynamin_N PF00350.23 KFM63946.1 - 3.8e-05 23.8 0.6 5.2e-05 23.4 0.2 1.4 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 KFM63946.1 - 0.03 14.6 0.0 0.056 13.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain Dynamin_M PF01031.20 KFM63947.1 - 3.5e-59 200.3 0.8 3.5e-59 200.3 0.8 1.6 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 KFM63947.1 - 5.9e-12 45.6 2.5 1.6e-11 44.2 1.6 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain Dynamin_N PF00350.23 KFM63947.1 - 1.5e-11 44.7 1.2 9.2e-11 42.1 0.0 2.7 2 1 0 2 2 2 1 Dynamin family adh_short PF00106.25 KFM63948.1 - 5e-28 97.9 0.4 9.5e-28 97.0 0.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM63948.1 - 3.3e-18 66.1 0.1 6.7e-18 65.1 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM63948.1 - 4.6e-06 26.7 0.0 9.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 KR domain PI3_PI4_kinase PF00454.27 KFM63949.1 - 3.9e-13 49.8 1.3 5.2e-13 49.4 1.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFM63949.1 - 2.9e-05 23.8 0.1 5.2e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KFM63950.1 - 1.7e-16 60.4 6.0 1.7e-16 60.4 6.0 2.1 2 1 0 2 2 2 1 FAT domain MitMem_reg PF13012.6 KFM63950.1 - 0.007 16.8 0.8 0.35 11.3 0.1 2.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Glu-tRNAGln PF02686.15 KFM63950.1 - 0.026 14.8 0.2 0.32 11.3 0.0 2.7 2 1 1 3 3 3 0 Glu-tRNAGln amidotransferase C subunit GlutR_dimer PF00745.20 KFM63950.1 - 0.16 12.4 2.0 4.3 7.8 0.3 3.1 2 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Cupin_8 PF13621.6 KFM63951.1 - 6.2e-31 108.0 1.2 6.2e-31 108.0 1.2 1.9 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 KFM63951.1 - 1.9e-06 28.3 0.1 6.1e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KFM63951.1 - 0.00053 19.6 0.1 0.0024 17.4 0.1 1.9 1 1 0 1 1 1 1 Cupin superfamily protein zf-H2C2_2 PF13465.6 KFM63952.1 - 4.6e-08 33.1 11.2 3.6e-07 30.3 3.5 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM63952.1 - 1.8e-07 31.3 15.3 0.00063 20.1 6.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM63952.1 - 1.9e-07 30.7 1.4 1.9e-07 30.7 1.4 2.8 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM63952.1 - 1.1e-06 28.9 13.2 0.0032 18.2 6.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM63952.1 - 0.00044 20.2 4.6 0.00044 20.2 4.6 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFM63952.1 - 0.015 15.0 2.7 0.34 10.6 0.1 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 KFM63952.1 - 0.021 15.1 7.3 0.14 12.4 7.2 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.22 KFM63952.1 - 0.029 14.3 7.7 0.26 11.2 3.3 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNHCP PF12647.7 KFM63952.1 - 0.42 10.6 6.5 0.92 9.5 6.5 1.6 1 1 0 1 1 1 0 RNHCP domain zf-C2HC_2 PF13913.6 KFM63952.1 - 1.6 8.7 11.9 0.11 12.4 4.7 2.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFM63952.1 - 3 8.3 12.6 3.4 8.1 3.3 2.9 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-ACC PF17848.1 KFM63952.1 - 4.1 7.6 8.0 1.3 9.2 0.2 2.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Mago_nashi PF02792.14 KFM63953.1 - 5.6e-78 259.9 0.5 6.2e-78 259.8 0.5 1.0 1 0 0 1 1 1 1 Mago nashi protein Choline_kinase PF01633.20 KFM63960.1 - 1.1e-53 182.0 0.0 1.6e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFM63960.1 - 1.4e-07 31.7 0.0 1.9e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFM63960.1 - 0.00014 21.3 0.1 0.0005 19.5 0.1 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase TED_complement PF07678.14 KFM63961.1 - 1.3e-90 303.6 0.0 1.8e-90 303.1 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 KFM63961.1 - 2.4e-22 79.4 1.3 7.2e-22 77.9 0.2 2.3 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain A2M PF00207.22 KFM63961.1 - 1.2e-16 60.3 0.0 2.8e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 KFM63961.1 - 2.5e-14 53.8 0.6 5.6e-14 52.7 0.6 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain Ldl_recept_a PF00057.18 KFM63961.1 - 0.00022 21.3 9.8 0.0004 20.5 9.8 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Prenyltrans PF00432.21 KFM63961.1 - 0.0025 17.5 0.0 0.47 10.2 0.0 3.4 3 0 0 3 3 3 1 Prenyltransferase and squalene oxidase repeat PRKCSH-like PF12999.7 KFM63961.1 - 0.0064 16.3 2.6 0.011 15.5 2.6 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like GEN1_C PF18380.1 KFM63961.1 - 0.096 13.6 0.2 12 6.8 0.1 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain SQHop_cyclase_C PF13243.6 KFM63961.1 - 0.11 11.6 0.0 15 4.5 0.0 2.3 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain MG4 PF17789.1 KFM63962.1 - 2.5e-05 24.3 0.4 0.00011 22.3 0.1 2.1 1 1 1 2 2 2 1 Macroglobulin domain MG4 MG2 PF01835.19 KFM63963.1 - 1.1e-17 64.3 0.2 1.8e-16 60.4 0.1 2.2 2 1 0 2 2 2 1 MG2 domain DUF4469 PF14734.6 KFM63963.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold DDE_1 PF03184.19 KFM63964.1 - 1.2e-17 64.1 0.5 2.7e-17 63.0 0.5 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM63964.1 - 1.7e-12 47.1 0.0 4.5e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF4259 PF14078.6 KFM63964.1 - 0.0023 18.7 1.8 0.047 14.4 0.4 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4259) Meis_PKNOX_N PF16493.5 KFM63965.1 - 1.5e-43 147.0 0.5 2.2e-43 146.5 0.5 1.2 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Sulfotransfer_1 PF00685.27 KFM63966.1 - 9.2e-21 74.5 0.0 1.1e-20 74.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM63966.1 - 6.5e-09 36.5 0.0 8.6e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family HTH_Tnp_Tc3_2 PF01498.18 KFM63968.1 - 2.2e-17 63.1 0.9 2.2e-17 63.1 0.9 1.6 1 1 1 2 2 2 1 Transposase HTH_32 PF13565.6 KFM63968.1 - 1.8e-05 25.3 0.7 3.5e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_21 PF13276.6 KFM63968.1 - 0.0002 21.5 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 HTH-like domain DDE_Tnp_ISAZ013 PF07592.11 KFM63968.1 - 0.036 13.0 0.1 0.045 12.7 0.1 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain PPR PF01535.20 KFM63969.1 - 0.012 15.8 0.0 1.4 9.3 0.0 3.7 5 0 0 5 5 5 0 PPR repeat TPR_12 PF13424.6 KFM63969.1 - 0.014 15.6 0.1 7.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM63969.1 - 0.054 13.6 0.9 5.1 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_long PF17177.4 KFM63969.1 - 0.059 12.7 0.2 0.22 10.9 0.1 1.8 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP TPR_8 PF13181.6 KFM63969.1 - 0.15 12.3 2.6 0.83 10.0 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DDE_3 PF13358.6 KFM63970.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease PRANC PF09372.10 KFM63970.1 - 0.06 13.7 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 PRANC domain AAA PF00004.29 KFM63972.1 - 7.4e-07 29.7 0.2 6.6e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFM63972.1 - 2.1e-05 24.6 0.0 0.00019 21.5 0.0 2.7 3 0 0 3 3 1 1 AAA domain AAA_22 PF13401.6 KFM63972.1 - 0.00015 22.0 3.7 0.00072 19.8 0.1 3.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFM63972.1 - 0.00033 20.4 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFM63972.1 - 0.00036 21.1 0.0 0.0014 19.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM63972.1 - 0.00046 20.6 1.1 0.0011 19.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain PhoH PF02562.16 KFM63972.1 - 0.0013 18.2 0.1 0.0041 16.6 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 KFM63972.1 - 0.0086 15.8 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFM63972.1 - 0.0097 15.4 0.4 0.035 13.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 KFM63972.1 - 0.015 14.9 0.0 0.083 12.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFM63972.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Spc7 PF08317.11 KFM63972.1 - 0.022 13.6 20.2 0.066 12.1 8.8 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_24 PF13479.6 KFM63972.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM63972.1 - 0.034 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFM63972.1 - 0.038 13.9 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain ResIII PF04851.15 KFM63972.1 - 0.041 13.9 0.0 0.041 13.9 0.0 3.4 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KFM63972.1 - 0.044 13.4 0.6 0.1 12.2 0.0 1.9 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 KFM63972.1 - 0.055 12.8 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFM63972.1 - 0.096 13.1 3.5 0.61 10.5 0.0 3.0 2 1 1 3 3 2 0 AAA ATPase domain RNA_helicase PF00910.22 KFM63972.1 - 0.14 12.5 2.7 0.16 12.4 0.0 2.6 3 0 0 3 3 1 0 RNA helicase DUF4020 PF13212.6 KFM63972.1 - 0.15 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) DUF4407 PF14362.6 KFM63972.1 - 0.66 9.3 14.0 0.068 12.5 7.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) EzrA PF06160.12 KFM63972.1 - 0.69 8.0 17.5 1.1 7.4 5.0 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA FapA PF03961.13 KFM63972.1 - 1.1 7.8 10.7 0.88 8.1 4.1 2.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A Nnf1 PF03980.14 KFM63972.1 - 1.8 9.0 12.5 2.2 8.7 3.9 3.1 2 0 0 2 2 2 0 Nnf1 GLE1 PF07817.13 KFM63972.1 - 2.2 7.4 7.2 1.2 8.3 0.0 2.8 3 0 0 3 3 3 0 GLE1-like protein DUF4201 PF13870.6 KFM63972.1 - 2.6 7.8 28.3 0.52 10.0 4.3 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4201) FUSC PF04632.12 KFM63972.1 - 2.7 6.4 4.5 5.8 5.3 4.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family GCV_H PF01597.19 KFM63973.1 - 4.6e-45 152.5 1.2 5.5e-45 152.2 1.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KFM63973.1 - 0.00037 20.3 0.5 0.00074 19.3 0.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HTH_Tnp_Tc3_2 PF01498.18 KFM63974.1 - 2.6e-16 59.6 2.2 5.1e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63974.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM63975.1 - 4.7e-16 58.8 0.1 5.5e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63975.1 - 7.4e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63975.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63975.1 - 0.0024 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63975.1 - 0.015 15.4 0.1 0.063 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM63975.1 - 0.034 14.2 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix RVT_1 PF00078.27 KFM63976.1 - 3.6e-10 39.8 0.2 7.5e-10 38.7 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFM63976.1 - 1.2e-05 25.2 0.1 3.2e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.18 KFM63977.1 - 2e-16 60.0 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM63977.1 - 9.9e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM63978.1 - 5.1e-16 58.8 0.1 6.1e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM63978.1 - 8.2e-16 58.0 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM63978.1 - 0.0016 19.0 1.2 0.0016 19.0 1.2 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM63978.1 - 0.0022 17.7 0.1 0.11 12.4 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM63978.1 - 0.017 15.3 0.1 0.067 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM63978.1 - 0.034 14.2 2.0 0.049 13.6 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM63978.1 - 0.095 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase RVT_1 PF00078.27 KFM63979.1 - 4.7e-13 49.2 0.0 4.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GED PF02212.18 KFM63980.1 - 2.2e-26 91.8 0.7 3.3e-26 91.3 0.7 1.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 KFM63980.1 - 6.3e-12 45.9 0.5 9.7e-12 45.3 0.5 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM63980.1 - 0.13 12.7 0.9 0.49 10.8 0.9 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain Dynamin_M PF01031.20 KFM63981.1 - 2.4e-91 305.9 0.7 2.4e-91 305.9 0.7 1.7 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 KFM63981.1 - 7.4e-55 185.6 0.1 1.9e-54 184.3 0.0 1.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFM63981.1 - 8.8e-05 22.6 0.0 0.00026 21.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4455 PF14643.6 KFM63981.1 - 0.067 11.8 0.5 0.12 11.1 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF4543 PF15076.6 KFM63981.1 - 0.08 13.1 0.6 0.16 12.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) AAA_28 PF13521.6 KFM63981.1 - 0.17 12.1 0.6 0.62 10.3 0.1 2.2 2 1 0 2 2 2 0 AAA domain CD36 PF01130.21 KFM63982.1 - 7.1e-125 417.2 3.0 9e-125 416.8 3.0 1.0 1 0 0 1 1 1 1 CD36 family HTH_Tnp_Tc3_2 PF01498.18 KFM63983.1 - 5.9e-09 36.0 3.3 3.1e-08 33.7 3.3 2.0 1 1 0 1 1 1 1 Transposase Pkinase PF00069.25 KFM63985.1 - 8.6e-39 133.5 0.1 1.5e-38 132.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM63985.1 - 9.6e-24 84.1 0.1 1.4e-23 83.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Atg14 PF10186.9 KFM63985.1 - 0.0018 17.4 8.6 0.0024 17.0 8.6 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KFM63985.1 - 0.0075 16.5 6.5 0.013 15.7 6.5 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KFM63985.1 - 0.012 15.7 12.6 0.02 15.0 12.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 KFM63985.1 - 0.013 15.7 9.5 0.019 15.2 9.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APH PF01636.23 KFM63985.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM63985.1 - 0.064 12.6 4.2 0.12 11.6 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Spc7 PF08317.11 KFM63985.1 - 0.088 11.7 17.7 0.12 11.3 17.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc29 PF17082.5 KFM63985.1 - 0.19 11.5 4.7 0.33 10.8 4.7 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF2911 PF11138.8 KFM63985.1 - 0.22 11.4 2.0 0.39 10.6 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) DUF874 PF05917.11 KFM63985.1 - 0.43 9.6 13.9 0.72 8.8 13.9 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) bZIP_1 PF00170.21 KFM63985.1 - 0.51 10.5 13.3 0.35 11.0 10.1 2.3 1 1 1 2 2 2 0 bZIP transcription factor PKcGMP_CC PF16808.5 KFM63985.1 - 0.65 9.9 29.5 0.23 11.3 9.5 3.6 1 1 3 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SEP PF08059.13 KFM63985.1 - 0.72 10.5 3.1 1.5 9.4 0.0 2.7 2 2 1 3 3 2 0 SEP domain ERM PF00769.19 KFM63985.1 - 0.91 9.3 19.3 1.2 8.8 19.1 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Csm1_N PF18504.1 KFM63985.1 - 0.94 9.9 15.8 3 8.3 8.2 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Spc42p PF11544.8 KFM63985.1 - 1.4 9.0 19.3 3.6 7.6 2.5 4.0 1 1 3 4 4 4 0 Spindle pole body component Spc42p DUF16 PF01519.16 KFM63985.1 - 3.2 8.3 15.6 8.2 7.0 15.5 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF641 PF04859.12 KFM63985.1 - 3.3 8.0 15.3 5.1 7.4 6.8 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4446 PF14584.6 KFM63985.1 - 5.3 7.0 9.3 2.3 8.2 6.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) FAM167 PF11652.8 KFM63985.1 - 7.2 7.2 8.7 4.2 7.9 5.1 2.2 2 0 0 2 2 2 0 FAM167 HIP1_clath_bdg PF16515.5 KFM63985.1 - 8.5 7.1 18.0 4.6 7.9 14.3 2.4 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4371 PF14291.6 KFM63986.1 - 2e-26 93.1 0.0 3.7e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM63986.1 - 6.6e-10 38.6 0.1 2e-09 37.1 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KFM63986.1 - 0.0039 17.0 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RSS_P20 PF11757.8 KFM63986.1 - 0.15 12.5 0.1 0.15 12.5 0.1 3.1 3 0 0 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM63987.1 - 1.3e-17 63.7 1.3 5.6e-16 58.6 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM63987.1 - 9.8e-12 44.8 0.0 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease p450 PF00067.22 KFM63989.1 - 1.1e-24 87.1 0.0 1.2e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.10 KFM63989.1 - 0.31 10.5 1.2 0.5 9.8 1.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ras PF00071.22 KFM63990.1 - 8.8e-61 204.2 0.1 1e-60 204.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM63990.1 - 3.6e-32 111.1 0.0 6.1e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM63990.1 - 2.3e-12 46.7 0.0 3.1e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM63990.1 - 1.8e-05 24.4 0.0 0.001 18.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM63990.1 - 3.5e-05 23.8 0.0 0.00015 21.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM63990.1 - 0.00042 20.3 0.1 0.95 9.4 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFM63990.1 - 0.0012 18.3 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFM63990.1 - 0.01 15.6 0.0 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFM63990.1 - 0.17 12.2 0.1 0.56 10.5 0.0 1.9 2 1 1 3 3 3 0 AAA domain DUF961 PF06125.11 KFM63993.1 - 0.2 12.1 11.4 15 6.0 0.2 6.0 2 2 6 8 8 8 0 Bacterial protein of unknown function (DUF961) TPX2_importin PF12214.8 KFM63994.1 - 6.5e-20 72.0 60.6 1.7e-11 44.6 7.3 5.9 3 2 3 6 6 6 5 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 KFM63994.1 - 1e-06 28.8 18.7 1e-06 28.8 18.7 5.3 5 0 0 5 5 5 2 Targeting protein for Xklp2 (TPX2) Pkinase_Tyr PF07714.17 KFM63995.1 - 2.3e-65 220.5 0.0 3.2e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM63995.1 - 8.5e-25 87.6 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFM63995.1 - 0.019 14.3 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KFM63996.1 - 2.3e-05 23.8 0.1 2.8e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM63996.1 - 0.022 14.1 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF2834 PF11196.8 KFM63996.1 - 0.023 15.0 0.2 0.036 14.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) DUF948 PF06103.11 KFM63996.1 - 0.42 10.9 1.5 0.68 10.2 1.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SKG6 PF08693.10 KFM63996.1 - 0.74 9.3 4.3 3.3 7.2 4.3 2.0 1 1 0 1 1 1 0 Transmembrane alpha-helix domain RED_N PF07808.13 KFM63997.1 - 0.31 10.6 5.2 0.39 10.3 5.2 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Recep_L_domain PF01030.24 KFM63998.1 - 3.1e-34 117.4 3.6 1.1e-26 93.1 0.4 2.7 3 0 0 3 3 3 2 Receptor L domain Furin-like PF00757.20 KFM63998.1 - 7.5e-31 107.0 43.6 1.2e-30 106.3 43.6 1.3 1 0 0 1 1 1 1 Furin-like cysteine rich region GF_recep_IV PF14843.6 KFM63998.1 - 1.1 9.1 46.3 0.52 10.1 31.7 2.6 1 1 1 2 2 2 0 Growth factor receptor domain IV HTH_Tnp_Tc3_2 PF01498.18 KFM64000.1 - 3.3e-15 56.1 1.5 6.9e-15 55.1 1.5 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64000.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64000.1 - 7.2 7.3 8.9 0.38 11.4 2.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Pkinase PF00069.25 KFM64001.1 - 2.1e-51 174.8 1.7 1.7e-50 171.8 1.7 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM64001.1 - 3.4e-29 101.9 0.5 3.6e-23 82.2 0.3 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DDE_3 PF13358.6 KFM64001.1 - 2.6e-06 27.3 0.0 5.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Haspin_kinase PF12330.8 KFM64001.1 - 4.6e-06 25.8 0.4 7.2e-06 25.2 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFM64001.1 - 1.5e-05 24.6 0.1 2.9e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFM64001.1 - 2.1e-05 24.0 0.7 3.7e-05 23.2 0.7 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM64001.1 - 2.2e-05 23.9 0.1 0.1 11.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.20 KFM64001.1 - 8.2e-05 22.3 0.2 0.00014 21.6 0.2 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KFM64001.1 - 0.00019 20.4 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM64001.1 - 0.00019 21.4 2.2 0.00064 19.7 0.0 2.7 3 1 1 4 4 4 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFM64001.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Ank_5 PF13857.6 KFM64002.1 - 3.7e-08 33.5 0.7 1.6e-05 25.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM64002.1 - 1.3e-07 32.1 0.0 3.4e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM64002.1 - 7.3e-05 22.9 0.2 0.13 12.9 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat IQ PF00612.27 KFM64002.1 - 0.00014 21.4 22.9 0.028 14.2 0.5 4.5 4 0 0 4 4 4 3 IQ calmodulin-binding motif Ank PF00023.30 KFM64002.1 - 0.011 16.1 0.5 1.2 9.8 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 KFM64002.1 - 0.05 14.2 0.6 2.3 8.9 0.0 3.1 1 1 2 3 3 3 0 Ankyrin repeats (many copies) CG-1 PF03859.16 KFM64003.1 - 1.5e-30 105.4 1.3 2.7e-30 104.5 1.3 1.5 1 0 0 1 1 1 1 CG-1 domain DUF4222 PF13973.6 KFM64003.1 - 0.16 11.6 0.6 0.31 10.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4222) Pol_alpha_B_N PF08418.10 KFM64003.1 - 0.41 10.6 9.4 0.074 13.0 4.2 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Kinesin PF00225.23 KFM64006.1 - 7.9e-86 288.0 0.4 1.4e-85 287.2 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KFM64006.1 - 3.2e-28 99.3 1.3 1.1e-27 97.6 0.0 2.7 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 KFM64006.1 - 1.5e-27 96.9 13.9 1.7e-21 77.2 1.2 4.1 4 1 1 5 5 5 2 Kinesin-associated CAP_GLY PF01302.25 KFM64006.1 - 5e-24 84.1 0.1 9.2e-24 83.3 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain KIF1B PF12423.8 KFM64006.1 - 3.7e-17 62.5 1.9 9.4e-17 61.2 0.3 2.6 2 0 0 2 2 2 1 Kinesin protein 1B Microtub_bd PF16796.5 KFM64006.1 - 2.9e-06 27.3 0.2 8.7e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding FHA PF00498.26 KFM64006.1 - 3.8e-06 27.2 0.0 3.3e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFM64006.1 - 0.0063 16.8 0.1 0.028 14.8 0.0 2.1 2 0 0 2 2 1 1 Inner membrane component of T3SS, cytoplasmic domain CBFD_NFYB_HMF PF00808.23 KFM64006.1 - 0.072 13.4 0.4 35 4.8 0.0 4.0 4 0 0 4 4 4 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Borrelia_REV PF03978.13 KFM64006.1 - 0.28 11.1 3.0 0.22 11.5 0.7 2.0 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein EAP30 PF04157.16 KFM64006.1 - 3.1 7.0 10.1 0.053 12.8 1.5 2.4 2 0 0 2 2 2 0 EAP30/Vps36 family DUF3377 PF11857.8 KFM64007.1 - 0.037 14.0 0.8 0.047 13.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Glt_symporter PF03616.14 KFM64009.1 - 0.055 12.1 0.6 0.063 11.9 0.6 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter p450 PF00067.22 KFM64010.1 - 1.2e-82 278.2 0.4 1.1e-81 275.0 0.4 1.9 1 1 0 1 1 1 1 Cytochrome P450 zf-CCHC PF00098.23 KFM64011.1 - 1.7e-06 27.9 2.5 1.7e-06 27.9 2.5 4.0 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_4 PF14392.6 KFM64011.1 - 0.014 15.1 4.5 0.32 10.8 0.9 3.1 3 0 0 3 3 3 0 Zinc knuckle Cas_TM1802 PF09484.10 KFM64011.1 - 0.064 12.0 1.2 0.083 11.6 1.2 1.0 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) zf-CCHC_5 PF14787.6 KFM64011.1 - 0.37 10.5 4.0 0.23 11.2 1.4 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KFM64011.1 - 0.62 10.1 7.0 0.23 11.5 3.6 2.1 1 1 1 2 2 2 0 Zinc knuckle fn3 PF00041.21 KFM64014.1 - 1.6e-44 150.2 10.9 2.8e-16 59.6 0.6 3.3 3 0 0 3 3 3 3 Fibronectin type III domain I-set PF07679.16 KFM64014.1 - 2.9e-09 36.9 0.1 4.8e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain Interfer-bind PF09294.10 KFM64014.1 - 7.9e-07 29.4 0.0 0.16 12.3 0.0 3.4 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Ig_3 PF13927.6 KFM64014.1 - 1.4e-05 25.6 1.5 3.8e-05 24.2 0.1 2.5 3 0 0 3 3 3 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM64014.1 - 6.6e-05 23.4 9.6 0.15 12.7 0.5 4.2 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 KFM64014.1 - 0.00037 20.8 0.6 0.0015 18.8 0.0 2.4 4 0 0 4 4 2 1 Immunoglobulin domain V-set PF07686.17 KFM64014.1 - 0.00038 20.6 0.1 0.0024 18.0 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFM64014.1 - 0.0014 18.7 0.0 0.0048 17.0 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain TMEM154 PF15102.6 KFM64014.1 - 0.013 15.4 1.0 0.043 13.7 1.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family fn3_2 PF16893.5 KFM64014.1 - 0.017 15.3 0.1 0.087 13.0 0.0 2.3 3 0 0 3 3 3 0 Fibronectin type III domain DUF2369 PF10179.9 KFM64014.1 - 0.027 14.9 0.0 9.7 6.7 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) TRP PF06011.12 KFM64014.1 - 0.038 12.7 0.3 0.068 11.9 0.2 1.4 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Tissue_fac PF01108.17 KFM64014.1 - 0.068 13.0 2.2 9.4 6.1 0.1 3.1 2 1 0 3 3 3 0 Tissue factor Shisa PF13908.6 KFM64014.1 - 0.08 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator F5_F8_type_C PF00754.25 KFM64014.1 - 0.23 11.6 2.4 1.1 9.4 0.1 2.6 2 1 0 2 2 2 0 F5/8 type C domain Arylsulfotran_N PF17425.2 KFM64014.1 - 0.53 10.4 3.7 1.3 9.1 0.3 2.8 3 0 0 3 3 2 0 Arylsulfotransferase Ig-like domain Ig_3 PF13927.6 KFM64015.1 - 5.1e-19 68.7 0.6 6.1e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM64015.1 - 1.7e-17 63.3 0.0 3.1e-10 40.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM64015.1 - 3.6e-13 49.5 0.2 4.8e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM64015.1 - 4.4e-13 49.4 0.1 4.1e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM64015.1 - 6.2e-05 23.1 0.1 0.57 10.4 0.0 2.8 2 1 1 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM64015.1 - 0.00053 20.0 0.4 0.22 11.6 0.1 2.4 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM64015.1 - 0.0019 17.7 0.3 0.0065 16.0 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM64015.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.6 2 0 0 2 2 2 0 C17orf99 Ig domain fn3 PF00041.21 KFM64016.1 - 2.5e-05 24.5 0.0 4.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain Trypan_PARP PF05887.11 KFM64016.1 - 1.1 9.2 7.7 0.42 10.6 5.1 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DDE_3 PF13358.6 KFM64017.1 - 0.00066 19.5 0.0 0.00067 19.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease I-set PF07679.16 KFM64019.1 - 4.7e-14 52.2 0.1 8.2e-06 25.8 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM64019.1 - 2.1e-11 44.2 0.2 1.4e-05 25.5 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM64019.1 - 3e-08 33.9 0.0 0.0043 17.4 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM64019.1 - 2e-07 31.1 0.0 0.02 15.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM64019.1 - 1.8e-06 28.1 0.0 0.001 19.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM64019.1 - 0.015 15.5 0.0 1.5 9.1 0.0 2.1 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFM64019.1 - 0.026 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM64019.1 - 0.027 14.9 0.0 4.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Herpes_gE PF02480.16 KFM64019.1 - 0.073 11.8 0.0 0.085 11.6 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ig_3 PF13927.6 KFM64020.1 - 4.6e-13 49.6 0.2 6e-13 49.2 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM64020.1 - 5.8e-12 45.5 0.0 7.1e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM64020.1 - 8.8e-11 41.8 0.3 1.2e-10 41.4 0.3 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM64020.1 - 5.7e-09 36.2 0.1 8.7e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM64020.1 - 2.9e-05 24.2 0.4 0.00015 21.9 0.4 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM64020.1 - 0.00015 21.8 0.1 0.00023 21.2 0.1 1.4 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFM64020.1 - 0.0012 18.8 0.1 0.008 16.2 0.1 2.0 1 1 0 1 1 1 1 C17orf99 Ig domain C1-set PF07654.15 KFM64020.1 - 0.0013 19.0 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain V-set_CD47 PF08204.11 KFM64020.1 - 0.086 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Shisa PF13908.6 KFM64021.1 - 0.02 15.1 0.1 0.02 15.1 0.1 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator I-set PF07679.16 KFM64023.1 - 7.6e-16 58.0 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM64023.1 - 4.8e-12 46.3 0.1 8.5e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM64023.1 - 6.7e-12 45.4 0.0 8.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM64023.1 - 6.3e-08 32.8 0.1 2.4e-06 27.7 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM64023.1 - 8.9e-08 32.4 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFM64023.1 - 4.3e-05 23.8 0.5 9.9e-05 22.6 0.1 1.8 2 1 0 2 2 2 1 Fibronectin type III domain Ig_5 PF16681.5 KFM64023.1 - 0.0016 18.8 0.0 0.046 14.1 0.0 2.1 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Receptor_2B4 PF11465.8 KFM64023.1 - 0.012 15.8 0.1 4.7 7.5 0.0 2.2 1 1 1 2 2 2 0 Natural killer cell receptor 2B4 Ig_6 PF18452.1 KFM64023.1 - 0.025 14.1 0.0 0.051 13.1 0.0 1.6 2 0 0 2 2 2 0 Immunoglobulin domain Ig_4 PF16680.5 KFM64023.1 - 0.084 13.1 0.0 0.79 10.0 0.0 2.1 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Piwi PF02171.17 KFM64026.1 - 2.5e-117 391.5 0.1 3e-117 391.2 0.1 1.0 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KFM64026.1 - 3.7e-05 23.9 0.0 0.00012 22.2 0.0 2.0 2 0 0 2 2 2 1 Mid domain of argonaute ArgoN PF16486.5 KFM64027.1 - 1.1e-30 107.0 0.0 2.9e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KFM64027.1 - 4e-26 91.5 0.6 6.1e-26 90.9 0.6 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KFM64027.1 - 8e-24 83.1 0.1 1.4e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFM64027.1 - 2.9e-15 56.3 0.1 7.5e-15 55.0 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KFM64027.1 - 3.9e-14 52.7 0.6 2.1e-13 50.3 0.2 2.3 2 0 0 2 2 2 1 Mid domain of argonaute BESS PF02944.20 KFM64028.1 - 1.8e-08 34.1 0.8 3.1e-08 33.3 0.8 1.4 1 0 0 1 1 1 1 BESS motif HAD_SAK_1 PF10307.9 KFM64028.1 - 0.025 14.4 0.3 0.035 13.9 0.3 1.3 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins V-ATPase_H_C PF11698.8 KFM64028.1 - 0.04 14.0 2.2 0.067 13.3 2.2 1.3 1 0 0 1 1 1 0 V-ATPase subunit H SH3_1 PF00018.28 KFM64034.1 - 2.1e-10 40.0 0.3 3.9e-10 39.2 0.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM64034.1 - 4.9e-07 29.5 0.6 9.8e-07 28.5 0.6 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM64034.1 - 1.2e-06 28.1 0.2 1.7e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Variant SH3 domain DDE_3 PF13358.6 KFM64035.1 - 9.6e-10 38.4 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM64036.1 - 6.9e-08 32.4 0.0 8.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RPAP1_N PF08621.10 KFM64036.1 - 0.25 11.2 1.5 0.52 10.1 1.5 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal HTH_Tnp_Tc3_2 PF01498.18 KFM64037.1 - 7.5e-16 58.1 6.5 1.2e-15 57.5 6.5 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64037.1 - 9.6e-14 51.4 0.0 2.3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64037.1 - 0.00058 20.4 1.5 0.00058 20.4 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM64037.1 - 0.0036 17.1 0.4 0.098 12.5 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64037.1 - 0.016 15.3 0.1 0.054 13.6 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM64037.1 - 0.024 14.7 2.4 0.029 14.4 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix 7tm_1 PF00001.21 KFM64038.1 - 9.1e-45 153.0 16.8 1.2e-44 152.6 16.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM64038.1 - 1.6e-05 24.4 14.4 3e-05 23.5 14.4 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM64038.1 - 2.2e-05 24.2 17.8 5e-05 23.1 17.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFM64038.1 - 0.0026 17.5 9.6 0.0061 16.4 9.6 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Saf_2TM PF18303.1 KFM64038.1 - 0.64 9.6 4.8 0.64 9.6 0.1 2.6 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain DUF4745 PF15923.5 KFM64039.1 - 4.1e-17 62.4 1.5 8.3e-17 61.4 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4745) PI-PLC-Y PF00387.19 KFM64039.1 - 0.0054 17.1 0.1 0.016 15.5 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Grp7_allergen PF16984.5 KFM64041.1 - 5.4e-08 33.1 0.0 7.1e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Group 7 allergen FMO-like PF00743.19 KFM64042.1 - 2.4e-89 300.2 0.0 2.7e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM64042.1 - 0.0044 16.3 0.1 0.066 12.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFM64043.1 - 5e-175 582.9 0.0 5.9e-175 582.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM64043.1 - 5e-22 78.5 0.0 3.7e-18 65.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM64043.1 - 3.9e-15 55.9 0.1 6.9e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM64043.1 - 3.3e-10 39.6 0.1 0.0001 21.6 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFM64043.1 - 1.5e-07 31.9 0.9 0.0081 16.7 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM64043.1 - 6.1e-06 25.6 0.0 0.033 13.4 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KFM64043.1 - 1e-05 25.7 0.4 6.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFM64043.1 - 9.1e-05 21.8 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain AlaDh_PNT_C PF01262.21 KFM64043.1 - 0.0028 17.0 0.1 0.25 10.6 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KFM64043.1 - 0.0031 17.2 1.6 1.6 8.2 0.0 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFM64043.1 - 0.0031 17.5 0.9 0.89 9.5 0.1 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFM64043.1 - 0.0055 15.8 0.6 2.8 6.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Peptidase_M17_N PF02789.17 KFM64043.1 - 0.0065 16.3 0.7 0.015 15.2 0.1 1.8 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain HI0933_like PF03486.14 KFM64043.1 - 0.0076 15.0 3.9 0.57 8.8 0.1 2.7 3 0 0 3 3 3 2 HI0933-like protein Shikimate_DH PF01488.20 KFM64043.1 - 0.0096 16.0 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KFM64043.1 - 0.08 12.3 0.6 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.12 KFM64043.1 - 0.1 12.2 0.0 7.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 KFM64043.1 - 0.12 12.8 0.1 21 5.6 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KFM64043.1 - 0.13 11.3 2.9 1.9 7.5 0.1 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Trypsin PF00089.26 KFM64044.1 - 7.9e-25 88.0 0.2 8.2e-25 87.9 0.2 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 KFM64044.1 - 0.095 12.2 0.0 0.095 12.2 0.0 1.1 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Trypsin PF00089.26 KFM64046.1 - 9.5e-55 185.8 0.3 1.1e-54 185.6 0.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM64046.1 - 1e-05 26.5 0.2 5e-05 24.2 0.2 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM64046.1 - 3.4e-05 24.2 0.1 0.00017 22.0 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 KFM64046.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 AMP-binding PF00501.28 KFM64050.1 - 3.6e-76 256.5 0.0 4.2e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM64050.1 - 0.015 16.3 0.0 0.044 14.8 0.0 1.8 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM64052.1 - 3.2e-14 52.9 1.0 7e-14 51.8 1.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64052.1 - 1e-13 51.3 0.0 1.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease COesterase PF00135.28 KFM64053.1 - 1.8e-120 403.3 0.0 2e-120 403.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM64053.1 - 8.2e-05 22.5 1.1 0.00058 19.8 1.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM64053.1 - 0.04 13.4 0.2 0.077 12.5 0.2 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFM64053.1 - 0.056 14.0 0.0 0.086 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.28 KFM64054.1 - 2.8e-23 82.6 0.4 3.4e-23 82.3 0.4 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF2185 PF09951.9 KFM64055.1 - 0.021 14.6 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) SSL_OB PF09199.10 KFM64055.1 - 0.055 13.8 0.4 0.093 13.1 0.4 1.5 1 1 0 1 1 1 0 Staphylococcal superantigen-like OB-fold domain zf-H2C2_2 PF13465.6 KFM64056.1 - 4e-77 251.4 65.5 6.8e-09 35.8 0.7 11.2 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64056.1 - 3e-53 175.4 81.7 5.7e-06 26.5 0.8 10.3 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64056.1 - 1.6e-39 131.1 80.1 0.00033 21.2 0.6 10.4 11 0 0 11 11 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM64056.1 - 8.2e-37 124.6 72.2 2.8e-05 24.3 0.2 10.3 10 0 0 10 10 10 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64056.1 - 2.2e-21 75.6 43.8 0.041 14.2 0.3 10.4 10 0 0 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM64056.1 - 3.9e-16 58.5 46.3 0.085 12.6 0.2 10.3 10 0 0 10 10 10 7 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM64056.1 - 7.9e-14 51.2 75.7 0.012 15.6 0.7 11.3 11 0 0 11 11 11 8 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM64056.1 - 5.2e-10 39.0 36.3 0.91 9.5 0.1 11.3 11 0 0 11 11 11 2 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM64056.1 - 2.4e-08 33.8 30.7 0.056 13.4 0.3 6.3 3 2 4 7 7 7 6 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KFM64056.1 - 2.4e-07 30.7 37.2 0.28 11.3 0.2 9.7 9 1 1 10 10 10 3 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 KFM64056.1 - 3.6e-06 26.6 45.6 0.21 11.4 0.1 9.1 9 0 0 9 9 9 5 zinc-finger C2H2-type BolA PF01722.18 KFM64056.1 - 5.8e-06 26.5 7.9 0.46 10.8 0.1 5.9 1 1 5 6 6 6 2 BolA-like protein Tox-HNH-HHH PF15637.6 KFM64056.1 - 0.00017 21.6 1.2 25 5.1 0.0 4.5 1 1 4 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF2256 PF10013.9 KFM64056.1 - 0.00027 21.0 35.5 8.6 6.6 0.1 9.8 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM64056.1 - 0.00029 20.9 50.8 4.3 7.5 0.1 10.4 9 1 1 10 10 10 1 DBF zinc finger DUF3396 PF11876.8 KFM64056.1 - 0.0003 20.3 0.0 7.2 6.0 0.0 4.6 1 1 4 6 6 6 0 Protein of unknown function (DUF3396) C1_1 PF00130.22 KFM64056.1 - 0.0005 19.9 49.4 0.072 13.0 1.5 8.7 3 2 4 8 8 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 KFM64056.1 - 0.00084 19.4 48.1 0.069 13.3 1.0 6.2 1 1 4 5 5 4 2 FYVE zinc finger Zn-ribbon_8 PF09723.10 KFM64056.1 - 0.0025 17.9 34.5 0.64 10.2 0.7 7.0 4 3 2 6 6 6 2 Zinc ribbon domain K_oxygenase PF13434.6 KFM64056.1 - 0.0039 16.4 0.2 3.9 6.5 0.0 3.8 1 1 4 5 5 5 1 L-lysine 6-monooxygenase (NADPH-requiring) zinc_ribbon_15 PF17032.5 KFM64056.1 - 0.0083 16.9 34.9 1.6 9.6 1.8 5.7 1 1 5 6 6 6 4 zinc-ribbon family zf-HIT PF04438.16 KFM64056.1 - 0.012 15.5 51.6 0.041 13.8 1.0 9.6 10 0 0 10 10 10 0 HIT zinc finger C5HCH PF17982.1 KFM64056.1 - 0.017 15.3 44.3 33 4.8 0.3 10.0 7 3 3 10 10 10 0 NSD Cys-His rich domain zf-CHCC PF10276.9 KFM64056.1 - 0.048 13.7 12.6 17 5.5 0.0 7.4 9 0 0 9 9 9 0 Zinc-finger domain zf-C2H2_9 PF16293.5 KFM64056.1 - 0.053 13.4 35.5 16 5.4 0.1 9.5 3 3 7 10 10 10 0 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KFM64056.1 - 0.099 12.3 43.8 0.37 10.4 0.4 9.2 6 3 4 10 10 10 0 MYST family zinc finger domain zf_UBZ PF18439.1 KFM64056.1 - 0.11 12.1 45.3 5.9 6.6 0.1 10.1 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger PqqA PF08042.11 KFM64056.1 - 0.34 11.0 0.5 5e+02 1.0 0.0 4.7 6 0 0 6 6 6 0 PqqA family zf-Dof PF02701.15 KFM64056.1 - 0.36 11.0 29.6 6.3 7.0 0.0 7.0 1 1 6 7 7 7 0 Dof domain, zinc finger YyzF PF14116.6 KFM64056.1 - 2.3 8.3 31.4 31 4.7 0.3 9.1 10 0 0 10 10 10 0 YyzF-like protein zf-H2C2_2 PF13465.6 KFM64057.1 - 3.2e-94 305.5 81.2 1.2e-08 34.9 0.4 13.0 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64057.1 - 1.1e-64 211.4 107.0 3e-06 27.4 1.7 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64057.1 - 4.1e-44 145.4 101.9 0.00033 21.2 1.2 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM64057.1 - 1.1e-36 124.2 99.0 0.00054 20.3 1.4 12.3 12 0 0 12 12 12 12 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM64057.1 - 1.6e-19 69.4 90.4 0.0038 17.2 1.8 12.4 12 0 0 12 12 12 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM64057.1 - 5.8e-18 64.3 61.1 0.027 14.2 0.0 12.3 12 0 0 12 12 12 10 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM64057.1 - 1.6e-14 53.7 71.0 0.043 14.1 0.6 12.5 11 1 1 12 12 12 8 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM64057.1 - 3.5e-12 46.1 37.8 0.0044 17.0 1.5 7.4 4 2 4 8 8 8 8 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM64057.1 - 1.1e-06 28.4 49.7 0.73 9.8 0.1 12.0 12 0 0 12 12 12 4 zinc-finger of a C2HC-type zf-CHCC PF10276.9 KFM64057.1 - 0.00012 22.1 18.4 22 5.2 0.0 10.1 12 0 0 12 12 12 0 Zinc-finger domain DUF2256 PF10013.9 KFM64057.1 - 0.00017 21.6 51.6 7.4 6.8 0.0 11.9 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.16 KFM64057.1 - 0.00025 20.9 74.7 0.15 12.0 1.2 11.8 12 0 0 12 12 12 3 HIT zinc finger FYVE PF01363.21 KFM64057.1 - 0.00026 21.1 69.0 0.57 10.4 10.4 6.6 1 1 5 6 6 5 2 FYVE zinc finger Tox-HNH-HHH PF15637.6 KFM64057.1 - 0.00027 21.0 5.9 8.8 6.5 0.0 5.3 1 1 6 7 7 7 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif TRAF6_Z2 PF18048.1 KFM64057.1 - 0.002 18.2 62.3 0.87 9.7 1.1 10.6 11 0 0 11 11 11 4 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_9 PF16293.5 KFM64057.1 - 0.0059 16.4 54.9 0.86 9.5 0.4 11.4 1 1 11 12 12 12 3 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM64057.1 - 0.075 13.8 51.7 1.1 10.1 2.4 6.2 2 2 3 6 6 6 0 zinc-ribbon family GAGA PF09237.11 KFM64057.1 - 0.14 12.0 33.7 0.25 11.2 1.1 8.0 2 2 8 10 10 10 0 GAGA factor C1_1 PF00130.22 KFM64057.1 - 0.15 11.9 72.3 9.6 6.2 0.2 10.5 1 1 6 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 KFM64057.1 - 0.21 11.4 0.1 0.21 11.4 0.1 11.0 12 0 0 12 12 12 0 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM64057.1 - 0.39 10.8 53.8 0.78 9.8 0.5 11.5 7 4 5 12 12 12 0 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM64057.1 - 0.41 10.8 65.9 3 8.0 0.2 11.7 12 0 0 12 12 12 0 DBF zinc finger PqqA PF08042.11 KFM64057.1 - 0.54 10.4 6.3 4.4e+02 1.2 0.0 6.5 9 0 0 9 9 8 0 PqqA family C5HCH PF17982.1 KFM64057.1 - 1 9.6 64.7 10 6.3 1.4 11.7 9 3 2 12 12 12 0 NSD Cys-His rich domain YyzF PF14116.6 KFM64057.1 - 1.3 9.1 42.8 28 4.8 0.5 11.3 12 0 0 12 12 12 0 YyzF-like protein zf-MYST PF17772.1 KFM64057.1 - 3.8 7.2 56.7 0.83 9.3 0.6 11.3 7 3 5 12 12 12 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 KFM64059.1 - 9.4e-122 392.6 111.5 3.6e-10 39.8 0.6 17.1 17 0 0 17 17 17 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64059.1 - 1e-78 255.6 122.6 1.7e-06 28.1 1.0 16.1 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64059.1 - 1.6e-55 181.0 123.3 0.00045 20.8 0.5 16.1 16 0 0 16 16 16 16 C2H2-type zinc finger zf-met PF12874.7 KFM64059.1 - 9.2e-48 159.3 122.6 0.00066 20.0 1.0 16.3 16 0 0 16 16 16 16 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64059.1 - 1.4e-29 101.7 92.2 0.0059 16.9 0.4 16.4 14 2 2 16 16 16 14 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM64059.1 - 9.1e-24 82.9 73.3 0.0044 16.7 0.6 16.2 16 0 0 16 16 16 10 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM64059.1 - 4.9e-23 80.6 107.6 0.23 11.5 0.2 16.7 16 1 0 16 16 16 15 C2H2-type zinc finger ADK_lid PF05191.14 KFM64059.1 - 8e-16 57.7 42.3 0.0064 16.4 0.9 10.0 6 3 4 10 10 10 8 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM64059.1 - 5.2e-15 54.9 47.3 4 7.4 0.0 16.1 16 0 0 16 16 16 2 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM64059.1 - 3.3e-09 36.7 64.4 13 6.0 0.1 15.7 15 1 1 16 16 16 0 DBF zinc finger Tox-HNH-HHH PF15637.6 KFM64059.1 - 2.3e-08 34.1 10.1 5.5 7.2 0.1 7.3 1 1 8 9 9 9 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF2256 PF10013.9 KFM64059.1 - 2.4e-07 30.8 52.3 7.2 6.8 0.1 15.4 16 0 0 16 16 16 0 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.18 KFM64059.1 - 4.4e-07 30.1 31.1 0.39 11.0 0.3 9.5 1 1 10 11 11 11 3 BolA-like protein zf-MYST PF17772.1 KFM64059.1 - 9.9e-06 25.1 67.4 0.9 9.2 0.2 15.2 11 4 5 16 16 16 3 MYST family zinc finger domain C1_1 PF00130.22 KFM64059.1 - 3.5e-05 23.6 81.2 2.2 8.2 1.9 14.1 4 2 10 14 14 14 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHCC PF10276.9 KFM64059.1 - 0.00017 21.6 26.9 1.1e+02 2.9 0.0 13.7 16 0 0 16 16 16 0 Zinc-finger domain zinc_ribbon_15 PF17032.5 KFM64059.1 - 0.00019 22.1 59.4 1.4 9.7 1.3 8.3 2 1 3 7 7 7 2 zinc-ribbon family FYVE PF01363.21 KFM64059.1 - 0.033 14.3 79.6 13 6.0 12.3 9.0 1 1 4 6 6 4 0 FYVE zinc finger DUF3846 PF12957.7 KFM64059.1 - 0.062 13.6 0.0 78 3.7 0.0 4.1 4 1 1 5 5 4 0 Domain of unknown function (DUF3846) zf-Sec23_Sec24 PF04810.15 KFM64059.1 - 0.067 13.2 62.8 0.97 9.5 0.1 15.0 10 5 6 16 16 16 0 Sec23/Sec24 zinc finger PqqA PF08042.11 KFM64059.1 - 0.098 12.7 11.1 6.1e+02 0.7 0.0 9.8 13 0 0 13 13 13 0 PqqA family K_oxygenase PF13434.6 KFM64059.1 - 0.12 11.5 5.6 14 4.7 0.1 5.2 2 1 3 6 6 6 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_kinase PF01513.21 KFM64059.1 - 0.13 11.4 0.1 14 4.8 0.1 3.8 1 1 0 1 1 1 0 ATP-NAD kinase zf-RRPl_C4 PF17026.5 KFM64059.1 - 0.37 10.9 60.0 0.7 10.0 6.8 7.1 1 1 8 9 9 9 0 Putative ribonucleoprotein zinc-finger pf C4 type Mga PF05043.13 KFM64059.1 - 0.74 10.4 2.8 4.7 7.9 0.0 3.5 4 0 0 4 4 4 0 Mga helix-turn-helix domain zf_UBZ PF18439.1 KFM64059.1 - 0.8 9.4 79.0 7.3 6.3 0.3 15.7 16 0 0 16 16 16 0 Ubiquitin-Binding Zinc Finger BHD_1 PF10403.9 KFM64059.1 - 0.84 9.5 10.6 3.1 7.7 0.0 5.8 6 3 1 7 7 5 0 Rad4 beta-hairpin domain 1 DUF2039 PF10217.9 KFM64059.1 - 8.2 6.8 59.9 1.1 9.6 3.5 7.4 1 1 8 9 9 9 0 Uncharacterized conserved protein (DUF2039) VWA_2 PF13519.6 KFM64062.1 - 0.00026 21.6 0.0 0.00042 20.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain RVT_1 PF00078.27 KFM64063.1 - 6.5e-37 127.2 0.2 9.7e-37 126.6 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFR_dimer PF04253.15 KFM64063.1 - 0.035 14.2 3.8 0.85 9.7 1.3 2.3 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain SH3_9 PF14604.6 KFM64064.1 - 1.4e-07 31.3 0.5 3e-07 30.2 0.5 1.5 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM64064.1 - 2.7e-07 30.2 0.1 4.1e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM64064.1 - 9.1e-07 28.4 0.7 0.019 14.6 0.1 2.2 2 0 0 2 2 2 2 SH3 domain Neur_chan_LBD PF02931.23 KFM64065.1 - 2.5e-34 118.6 0.1 2.9e-34 118.4 0.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain TMEM189_B_dmain PF10520.9 KFM64067.1 - 8.5e-42 143.2 3.2 9.5e-42 143.0 3.2 1.0 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain HTH_Tnp_Tc3_2 PF01498.18 KFM64068.1 - 5.1e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64068.1 - 1.3e-13 50.9 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64068.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64068.1 - 0.0029 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64068.1 - 2.2 8.9 13.7 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain RT_RNaseH_2 PF17919.1 KFM64069.1 - 1e-30 105.7 0.0 4.8e-30 103.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM64069.1 - 2.7e-29 101.5 0.0 1.3e-28 99.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM64069.1 - 2e-28 99.4 0.1 5.6e-28 98.0 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM64069.1 - 1.9e-18 66.7 0.0 3.6e-17 62.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM64069.1 - 2.1e-16 59.7 0.0 7.7e-16 58.0 0.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain Arc_C PF18162.1 KFM64069.1 - 3.6e-05 23.5 1.7 0.00013 21.7 0.4 2.7 3 0 0 3 3 3 1 Arc C-lobe zf-H2C2 PF09337.10 KFM64069.1 - 0.0015 18.7 0.0 0.004 17.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM64069.1 - 0.021 15.1 2.8 0.23 11.8 0.0 3.7 3 0 0 3 3 3 0 Retrotransposon gag protein HTH_Tnp_Tc3_2 PF01498.18 KFM64070.1 - 1.8e-16 60.1 2.1 3.2e-16 59.3 2.1 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64070.1 - 6.5e-12 45.4 0.0 1.6e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 KFM64070.1 - 5.7e-05 23.2 1.0 0.00015 21.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM64070.1 - 0.013 14.9 1.1 0.12 11.8 0.0 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 KFM64070.1 - 0.024 14.3 0.0 0.09 12.4 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFM64070.1 - 0.034 14.0 0.4 0.08 12.8 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Kelch_2 PF07646.15 KFM64070.1 - 0.56 10.3 2.4 1.3 9.1 0.6 2.3 2 0 0 2 2 2 0 Kelch motif PAP_assoc PF03828.19 KFM64073.1 - 4.9e-10 39.5 0.2 1.7e-09 37.8 0.2 2.0 1 1 0 1 1 1 1 Cid1 family poly A polymerase Ribosomal_L13e PF01294.18 KFM64074.1 - 0.086 12.7 1.8 0.12 12.2 1.8 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e tRNA-synt_1c PF00749.21 KFM64074.1 - 0.21 10.4 3.2 0.22 10.4 3.2 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Rad51 PF08423.11 KFM64075.1 - 1.8e-15 56.9 0.1 2.1e-15 56.7 0.1 1.0 1 0 0 1 1 1 1 Rad51 DnaB_C PF03796.15 KFM64075.1 - 0.0026 17.2 0.7 0.003 16.9 0.7 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Elong_Iki1 PF10483.9 KFM64075.1 - 0.013 15.1 0.2 0.013 15.1 0.2 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 KFM64075.1 - 0.016 14.8 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KFM64075.1 - 0.03 13.7 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 KaiC 4HFCP_synth PF04476.13 KFM64075.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 4-HFC-P synthase HTH_Tnp_Tc3_2 PF01498.18 KFM64076.1 - 1.3e-17 63.8 1.8 2.4e-17 62.9 1.8 1.4 1 0 0 1 1 1 1 Transposase HTH_Crp_2 PF13545.6 KFM64076.1 - 0.0002 21.2 0.9 0.0031 17.5 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_32 PF13565.6 KFM64076.1 - 0.00044 20.8 1.0 0.00083 19.9 1.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 KFM64076.1 - 0.0027 17.2 1.6 0.48 10.0 0.0 3.2 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_33 PF13592.6 KFM64076.1 - 0.014 15.1 0.4 0.025 14.2 0.4 1.4 1 0 0 1 1 1 0 Winged helix-turn helix MarR_2 PF12802.7 KFM64076.1 - 0.023 14.6 0.5 0.85 9.6 0.0 2.6 2 1 0 2 2 2 0 MarR family HTH_21 PF13276.6 KFM64076.1 - 0.081 13.1 0.9 0.23 11.6 1.0 1.9 1 1 0 1 1 1 0 HTH-like domain HTH_26 PF13443.6 KFM64076.1 - 0.1 13.0 0.9 6.6 7.3 0.3 2.7 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain Mito_carr PF00153.27 KFM64077.1 - 1.2e-31 108.4 0.1 2.7e-10 40.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein YdiH PF15930.5 KFM64077.1 - 0.14 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Abhydrolase_1 PF00561.20 KFM64078.1 - 9.3e-07 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM64078.1 - 2.2e-06 27.1 0.0 3.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM64078.1 - 0.00043 20.9 0.0 0.00054 20.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KFM64078.1 - 0.005 15.6 0.0 0.0079 14.9 0.0 1.3 1 0 0 1 1 1 1 Ndr family Palm_thioest PF02089.15 KFM64078.1 - 0.051 13.4 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Cys_rich_FGFR PF00839.17 KFM64079.1 - 1e-171 557.3 124.7 2e-14 53.5 0.7 16.3 17 0 0 17 17 17 16 Cysteine rich repeat DUF445 PF04286.12 KFM64079.1 - 0.017 15.0 0.2 0.048 13.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MRAP PF15183.6 KFM64080.1 - 0.16 11.9 5.0 0.3 11.0 5.0 1.6 1 1 0 1 1 1 0 Melanocortin-2 receptor accessory protein family TAFH PF07531.14 KFM64081.1 - 7e-28 96.6 0.4 1.5e-27 95.5 0.1 1.7 2 0 0 2 2 2 1 NHR1 homology to TAF NHR2 PF08788.11 KFM64081.1 - 4.5e-15 55.2 0.4 1e-14 54.0 0.4 1.5 1 0 0 1 1 1 1 NHR2 domain like FNIP_M PF14637.6 KFM64081.1 - 0.34 10.9 2.2 0.38 10.7 0.2 1.9 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain HTH_Tnp_Tc3_2 PF01498.18 KFM64082.1 - 3.8e-16 59.1 3.6 5.4e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64082.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64082.1 - 2.2e-08 33.7 0.2 5.4e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64082.1 - 0.042 13.7 0.6 0.12 12.2 0.6 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM64082.1 - 7.6 7.2 16.2 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain PIF1 PF05970.14 KFM64083.1 - 2.5e-05 23.6 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase DUF4515 PF14988.6 KFM64083.1 - 0.034 14.0 2.8 0.051 13.4 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) HTH_Tnp_Tc3_2 PF01498.18 KFM64084.1 - 2.2e-16 59.9 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64084.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CUB PF00431.20 KFM64085.1 - 1.5e-10 41.4 2.1 0.0018 18.6 0.0 5.4 5 1 0 5 5 5 3 CUB domain PgaD PF13994.6 KFM64085.1 - 0.072 13.1 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 PgaD-like protein Ldl_recept_a PF00057.18 KFM64086.1 - 1.1e-07 31.9 6.3 1.8e-07 31.3 6.3 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.7 KFM64086.1 - 4.6e-05 23.3 1.3 5e-05 23.2 1.3 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like HTH_Tnp_Tc3_2 PF01498.18 KFM64087.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64087.1 - 7.7e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM64088.1 - 1.1e-07 31.7 0.0 1.7e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64089.1 - 7e-13 48.6 0.2 1.3e-12 47.7 0.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64089.1 - 2.5e-09 37.0 0.0 4.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64089.1 - 0.0024 18.4 5.6 0.0027 18.3 1.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM64089.1 - 0.004 17.2 0.3 0.031 14.3 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix HTH_23 PF13384.6 KFM64089.1 - 0.033 14.0 1.4 0.53 10.2 0.1 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 KFM64089.1 - 1.2 9.3 3.5 6.1 7.1 0.2 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain GBP_C PF02841.14 KFM64090.1 - 0.06 12.8 0.0 0.061 12.7 0.0 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Ion_trans PF00520.31 KFM64091.1 - 1.8e-70 237.0 11.5 2.3e-70 236.6 11.5 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM64091.1 - 0.0053 15.5 10.5 0.057 12.1 2.3 2.3 2 0 0 2 2 2 2 Polycystin cation channel Sigma_reg_N PF13800.6 KFM64091.1 - 0.042 14.1 4.2 3.4 8.0 0.0 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Lustrin_cystein PF14625.6 KFM64091.1 - 0.096 13.1 0.6 0.19 12.1 0.6 1.4 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain SieB PF14163.6 KFM64091.1 - 0.19 11.2 0.1 0.19 11.2 0.1 2.2 3 0 0 3 3 3 0 Super-infection exclusion protein B FSAP_sig_propep PF03032.15 KFM64091.1 - 0.73 9.9 2.4 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide COesterase PF00135.28 KFM64092.1 - 1.3e-29 103.5 0.0 1.5e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family FYVE PF01363.21 KFM64093.1 - 2.4e-19 69.2 8.6 5.1e-19 68.2 8.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFM64093.1 - 5e-08 33.4 0.1 1.5e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.16 KFM64093.1 - 0.00092 19.4 5.4 0.002 18.3 5.4 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger PH_13 PF16652.5 KFM64093.1 - 0.018 14.8 0.9 0.67 9.7 0.9 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFM64093.1 - 0.031 14.2 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF1835 PF08874.10 KFM64093.1 - 0.093 12.9 0.1 0.32 11.2 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1835) Amidinotransf PF02274.17 KFM64094.1 - 5.2e-13 48.8 0.0 8.9e-11 41.5 0.0 2.1 1 1 0 1 1 1 1 Amidinotransferase Sigma70_r1_1 PF03979.14 KFM64094.1 - 0.11 12.5 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 LST1 PF05083.13 KFM64099.1 - 0.11 12.7 0.1 0.18 12.1 0.1 1.5 1 1 0 1 1 1 0 LST-1 protein dCMP_cyt_deam_1 PF00383.23 KFM64101.1 - 2.5e-28 97.9 0.1 3.6e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFM64101.1 - 3.8e-15 55.9 0.0 6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 KFM64101.1 - 0.012 15.7 0.5 0.033 14.3 0.4 1.8 1 1 1 2 2 2 0 APOBEC3 SNAD4 PF18750.1 KFM64101.1 - 0.02 15.0 0.2 0.036 14.2 0.2 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4_like PF18774.1 KFM64101.1 - 0.026 14.5 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase FGGY_C PF02782.16 KFM64102.1 - 2.4e-45 154.7 0.0 3.5e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFM64102.1 - 3.2e-25 89.1 0.0 5.9e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain zf-H2C2_2 PF13465.6 KFM64103.1 - 4.6e-34 115.3 57.5 1.7e-06 28.2 0.6 8.8 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64103.1 - 1.7e-30 103.7 67.4 7.8e-06 26.1 1.4 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64103.1 - 5.3e-24 82.8 61.9 0.00099 19.8 1.4 8.3 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM64103.1 - 2.1e-13 50.1 35.9 0.025 14.8 0.8 8.4 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM64103.1 - 7.5e-10 38.6 53.1 0.01 15.8 0.3 8.2 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 KFM64103.1 - 2.6e-08 34.0 43.2 0.095 13.1 1.9 8.3 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFM64103.1 - 1.5e-06 28.5 52.2 0.027 14.9 1.9 7.8 2 1 6 8 8 8 5 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KFM64103.1 - 0.0094 16.0 29.4 2.3 8.4 0.8 6.2 2 1 4 6 6 6 3 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFM64103.1 - 0.025 14.3 0.7 0.025 14.3 0.7 7.2 8 1 0 8 8 7 0 zinc-finger C2H2-type zf-CHCC PF10276.9 KFM64103.1 - 0.16 12.1 0.1 0.16 12.1 0.1 6.5 7 0 0 7 7 7 0 Zinc-finger domain FYVE PF01363.21 KFM64103.1 - 0.39 10.9 41.3 1.2e+02 2.9 0.2 6.0 2 1 2 4 4 4 0 FYVE zinc finger ADK_lid PF05191.14 KFM64103.1 - 0.81 9.7 29.8 3.5 7.7 0.1 5.3 5 1 0 5 5 5 0 Adenylate kinase, active site lid BolA PF01722.18 KFM64103.1 - 1.3 9.4 5.9 59 4.0 0.4 5.0 3 2 2 5 5 5 0 BolA-like protein zf-C2HC_2 PF13913.6 KFM64103.1 - 7 6.7 48.3 1.2 9.1 0.2 8.2 8 0 0 8 8 8 0 zinc-finger of a C2HC-type PP2C_2 PF13672.6 KFM64105.1 - 1.7e-06 27.8 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFM64105.1 - 0.00099 19.1 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HTH_Tnp_Tc3_2 PF01498.18 KFM64106.1 - 5.9e-12 45.7 1.8 5.9e-12 45.7 1.8 1.7 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM64106.1 - 2.1e-06 27.4 1.2 1.1e-05 25.0 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64106.1 - 0.0041 16.9 1.7 0.01 15.6 0.4 2.3 2 0 0 2 2 2 1 Homeodomain-like domain DUF4081 PF13312.6 KFM64106.1 - 0.023 14.9 0.6 0.041 14.1 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4081) HTH_32 PF13565.6 KFM64106.1 - 0.023 15.3 2.7 0.023 15.3 2.7 2.3 3 0 0 3 3 3 0 Homeodomain-like domain DUF3880 PF12996.7 KFM64106.1 - 0.033 14.3 0.1 1.4 9.0 0.1 3.3 2 1 1 3 3 3 0 DUF based on E. rectale Gene description (DUF3880) HTH_28 PF13518.6 KFM64106.1 - 0.45 10.7 6.7 0.84 9.8 1.2 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain HEAT PF02985.22 KFM64108.1 - 0.0057 16.8 0.5 2.7 8.5 0.5 2.9 2 0 0 2 2 2 2 HEAT repeat CLASP_N PF12348.8 KFM64108.1 - 0.0063 16.1 0.0 0.014 15.0 0.0 1.5 1 1 1 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 KFM64108.1 - 0.068 13.2 0.3 0.7 9.9 0.1 2.3 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KFM64108.1 - 0.1 12.5 0.1 0.46 10.4 0.1 2.0 1 1 0 1 1 1 0 UME (NUC010) domain HEAT PF02985.22 KFM64109.1 - 1e-09 37.8 0.0 0.0046 17.1 0.0 3.4 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KFM64109.1 - 0.00011 22.5 0.0 0.0003 21.1 0.0 1.7 1 1 0 1 1 1 1 HEAT repeats Cnd1 PF12717.7 KFM64109.1 - 0.00058 19.9 0.1 0.031 14.3 0.0 2.5 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 PC_rep PF01851.22 KFM64109.1 - 0.016 15.6 0.0 11 6.6 0.0 3.1 3 0 0 3 3 3 0 Proteasome/cyclosome repeat RasGEF_N_2 PF14663.6 KFM64109.1 - 0.018 15.5 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Chromo_shadow PF01393.19 KFM64110.1 - 1.3e-27 95.6 0.5 1.9e-25 88.7 0.0 2.6 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFM64110.1 - 8.1e-22 76.9 2.1 3.5e-17 62.0 1.3 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain TMEM70 PF06979.12 KFM64111.1 - 7e-38 130.0 1.3 9.8e-38 129.6 1.3 1.2 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex DUF1411 PF07199.11 KFM64113.1 - 0.2 11.3 0.1 0.23 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) Exo_endo_phos PF03372.23 KFM64114.1 - 0.00015 21.3 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SURF4 PF02077.15 KFM64115.1 - 8.9e-120 399.3 8.3 1e-119 399.1 8.3 1.0 1 0 0 1 1 1 1 SURF4 family SURF2 PF05477.11 KFM64115.1 - 2.1e-12 47.3 0.0 2.4e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DoxX PF07681.12 KFM64115.1 - 0.02 15.5 2.4 0.02 15.5 2.4 3.4 3 1 1 4 4 4 0 DoxX Dimer_Tnp_hAT PF05699.14 KFM64116.1 - 0.014 15.2 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region GluRS_N PF18466.1 KFM64118.1 - 0.083 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain RVT_1 PF00078.27 KFM64119.1 - 0.00063 19.3 0.0 0.0021 17.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Stn1_C PF12659.7 KFM64119.1 - 0.054 13.5 0.3 0.054 13.5 0.3 2.1 2 1 1 3 3 3 0 Telomere capping C-terminal wHTH DUF1177 PF06675.11 KFM64119.1 - 0.065 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) Tox-MPTase5 PF15641.6 KFM64120.1 - 0.033 14.2 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 5 Trypsin PF00089.26 KFM64121.1 - 6e-07 29.5 0.0 6e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KFM64122.1 - 7.8e-09 35.7 0.0 7.8e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM64122.1 - 0.0058 17.0 0.0 0.0063 16.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF4777 PF16007.5 KFM64122.1 - 0.045 14.0 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Trypsin PF00089.26 KFM64123.1 - 1.5e-12 47.8 0.0 1.6e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin Synapsin PF02078.16 KFM64125.1 - 0.021 15.1 0.4 0.2 11.9 0.0 2.3 2 1 1 3 3 3 0 Synapsin, N-terminal domain DUF1731 PF08338.11 KFM64125.1 - 0.032 14.1 0.0 5.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Fucose_iso_N1 PF07881.12 KFM64127.1 - 0.018 14.9 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain Fucose_iso_N1 PF07881.12 KFM64128.1 - 0.071 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain ETRAMP PF09716.10 KFM64128.1 - 0.076 13.1 3.3 0.22 11.6 0.1 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Porin_3 PF01459.22 KFM64129.1 - 1e-72 244.8 4.8 1.2e-72 244.7 4.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin IL3Ra_N PF18611.1 KFM64129.1 - 0.087 12.8 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 IL-3 receptor alpha chain N-terminal domain RNase_T PF00929.24 KFM64131.1 - 1.4e-06 29.0 0.0 2.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 KFM64131.1 - 7.4e-05 23.1 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 ElonginA binding-protein 1 CHORD PF04968.12 KFM64131.1 - 0.032 15.0 3.1 0.072 13.8 3.1 1.6 1 0 0 1 1 1 0 CHORD Anoctamin PF04547.12 KFM64132.1 - 0.054 12.3 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Anoctamin PF04547.12 KFM64133.1 - 3.6e-99 332.6 8.8 4.1e-99 332.5 8.8 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Smim3 PF17307.2 KFM64133.1 - 0.15 11.6 3.0 0.55 9.8 3.0 1.9 1 0 0 1 1 1 0 Small integral membrane protein 3 AC_N PF16214.5 KFM64133.1 - 0.58 9.2 2.2 1.2 8.2 2.2 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region LRR19-TM PF15176.6 KFM64133.1 - 1 9.4 5.2 8.4 6.4 0.0 2.8 2 1 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Anoct_dimer PF16178.5 KFM64134.1 - 1.3e-10 41.4 0.2 1.7e-10 41.0 0.2 1.2 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin GGDEF_2 PF17853.1 KFM64134.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 GGDEF-like domain Hydrolase_4 PF12146.8 KFM64135.1 - 1.6e-11 43.9 0.0 1.1e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM64135.1 - 1.2e-06 29.3 0.2 4.4e-06 27.5 0.2 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFM64135.1 - 6.2e-06 25.8 0.0 0.00064 19.3 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFM64135.1 - 3e-05 23.8 0.2 0.0079 15.9 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 KFM64135.1 - 0.00069 18.7 0.0 0.00093 18.3 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 KFM64135.1 - 0.0048 16.5 0.0 0.0076 15.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.12 KFM64135.1 - 0.016 15.1 0.0 0.93 9.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 KFM64135.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Asp2 PF16929.5 KFM64135.1 - 0.033 13.2 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Abhydrolase_2 PF02230.16 KFM64135.1 - 0.05 13.4 0.1 0.32 10.8 0.1 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 KFM64135.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_6 PF08030.12 KFM64136.1 - 4e-10 40.0 0.0 4.8e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFM64138.1 - 3.1e-17 62.9 14.2 3.1e-17 62.9 14.2 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFM64138.1 - 3.7e-16 59.2 0.0 1.1e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain EF-hand_7 PF13499.6 KFM64138.1 - 1.5e-14 54.1 8.4 9.3e-09 35.6 0.8 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM64138.1 - 2e-14 51.9 4.2 1.9e-05 23.9 0.2 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFM64138.1 - 2.2e-10 39.6 2.5 0.00092 19.0 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFM64138.1 - 5.3e-09 35.2 0.7 0.0026 17.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFM64138.1 - 5.4e-08 32.6 6.6 0.0032 17.3 0.1 4.3 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.7 KFM64138.1 - 0.096 12.6 0.9 0.57 10.2 0.1 2.4 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand SpoVIF PF14069.6 KFM64138.1 - 0.21 11.4 0.2 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Stage VI sporulation protein F An_peroxidase PF03098.15 KFM64139.1 - 1.3e-85 288.0 0.1 1.8e-85 287.6 0.1 1.2 1 0 0 1 1 1 1 Animal haem peroxidase LapA_dom PF06305.11 KFM64139.1 - 0.0069 16.2 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain HTH_Tnp_Tc3_2 PF01498.18 KFM64140.1 - 2.1e-16 59.9 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64140.1 - 7.7e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Patatin PF01734.22 KFM64142.1 - 0.13 12.4 0.7 0.14 12.3 0.7 1.0 1 0 0 1 1 1 0 Patatin-like phospholipase HTH_Tnp_Tc3_2 PF01498.18 KFM64143.1 - 4.3e-16 58.9 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64143.1 - 7.4e-14 51.7 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64143.1 - 2.1e-07 30.6 1.4 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64143.1 - 0.0025 17.6 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64143.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain SPRY PF00622.28 KFM64144.1 - 3.8e-18 65.8 0.1 6.9e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 KFM64144.1 - 0.0011 19.3 1.1 0.0044 17.4 0.3 2.1 2 0 0 2 2 2 1 SOCS box DUF2205 PF10224.9 KFM64145.1 - 0.0012 18.8 1.0 0.0012 18.8 1.0 2.2 2 1 0 2 2 2 1 Short coiled-coil protein YABBY PF04690.13 KFM64145.1 - 0.061 13.9 1.0 0.081 13.5 1.0 1.1 1 0 0 1 1 1 0 YABBY protein FBPase PF00316.20 KFM64145.1 - 0.11 12.0 0.5 0.14 11.7 0.5 1.1 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain SlyX PF04102.12 KFM64145.1 - 0.11 13.1 3.2 0.24 12.1 3.2 1.6 1 0 0 1 1 1 0 SlyX DUF948 PF06103.11 KFM64145.1 - 0.32 11.3 2.8 0.35 11.1 1.5 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3510 PF12022.8 KFM64146.1 - 1.4e-34 119.2 1.2 3.8e-34 117.8 0.1 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF3510) CCDC142 PF14923.6 KFM64146.1 - 0.011 14.5 3.1 0.28 9.9 3.1 2.2 1 1 0 1 1 1 0 Coiled-coil protein 142 DHR10 PF18595.1 KFM64146.1 - 0.75 9.9 5.0 0.76 9.8 0.1 3.1 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain DUF1751 PF08551.10 KFM64147.1 - 6e-26 90.9 3.5 6e-26 90.9 3.5 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) HTH_Tnp_Tc3_2 PF01498.18 KFM64148.1 - 4.8e-16 58.8 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64148.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64148.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64148.1 - 0.0026 17.5 0.6 0.0076 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64148.1 - 2.2 8.9 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain PIP49_C PF12260.8 KFM64149.1 - 6.5e-45 153.1 0.1 7.9e-45 152.8 0.1 1.0 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Haspin_kinase PF12330.8 KFM64149.1 - 0.076 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Frtz PF11768.8 KFM64151.1 - 0.013 13.8 0.9 0.013 13.8 0.9 1.0 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Importin_rep_4 PF18808.1 KFM64152.1 - 6.2e-27 93.7 0.5 8.4e-26 90.1 0.0 3.4 3 0 0 3 3 2 1 Importin repeat HEAT_2 PF13646.6 KFM64152.1 - 2.9e-17 62.8 0.2 0.0012 19.2 0.0 7.5 6 3 2 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 KFM64152.1 - 9.6e-16 57.9 0.1 0.00023 21.6 0.0 7.9 7 1 1 8 8 7 3 HEAT-like repeat HEAT PF02985.22 KFM64152.1 - 3.1e-15 55.0 14.6 1.5e-05 24.8 0.0 10.5 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KFM64152.1 - 1.6e-09 38.3 1.6 0.0016 19.0 0.0 7.1 4 2 3 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFM64152.1 - 1e-08 35.4 4.3 0.00034 20.7 0.0 4.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KFM64152.1 - 4.5e-07 29.8 1.2 1.3 8.8 0.0 5.2 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis Importin_rep_6 PF18829.1 KFM64152.1 - 1.4e-06 28.3 0.3 8.5e-06 25.9 0.1 2.5 2 0 0 2 2 2 1 Importin repeat 6 Arm PF00514.23 KFM64152.1 - 1.8e-06 27.8 0.2 8.5 6.6 0.0 6.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KFM64152.1 - 0.0062 15.7 7.4 1.3 8.1 0.1 5.1 6 1 1 7 7 7 2 RNAPII transcription regulator C-terminal Ku_PK_bind PF08785.11 KFM64152.1 - 0.074 13.2 0.4 0.55 10.4 0.1 2.5 2 0 0 2 2 2 0 Ku C terminal domain like DUF5584 PF17822.1 KFM64152.1 - 0.08 12.4 0.0 0.28 10.6 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5584) YcbB PF08664.10 KFM64152.1 - 0.21 11.6 0.8 0.97 9.5 0.0 2.4 3 0 0 3 3 2 0 YcbB domain IBN_N PF03810.19 KFM64152.1 - 0.78 9.7 4.6 1.2 9.1 0.1 3.5 5 0 0 5 5 5 0 Importin-beta N-terminal domain Sec7_N PF12783.7 KFM64152.1 - 2.3 8.1 6.2 40 4.1 0.3 4.7 4 2 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Annexin PF00191.20 KFM64156.1 - 6.7e-93 304.8 6.7 1.4e-24 85.9 0.1 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFM64156.1 - 8.4e-05 22.4 0.0 6 6.8 0.0 4.0 3 1 0 4 4 4 3 Myb DNA-binding like Sigma70_ner PF04546.13 KFM64156.1 - 0.22 11.4 1.8 1.1 9.1 0.0 2.7 3 1 1 4 4 4 0 Sigma-70, non-essential region DAO PF01266.24 KFM64157.1 - 4.7e-39 135.0 0.0 5.4e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM64157.1 - 0.12 11.6 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFM64157.1 - 0.15 11.3 0.0 1.3 8.3 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KFM64157.1 - 0.16 12.6 0.2 0.41 11.2 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFM64157.1 - 0.2 11.6 0.7 1.2 9.1 0.7 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding DUF2695 PF10905.8 KFM64158.1 - 0.07 13.4 0.0 0.098 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) zf-H2C2_2 PF13465.6 KFM64160.1 - 1.6e-06 28.2 12.7 0.00011 22.4 1.5 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM64160.1 - 0.021 14.5 7.8 0.021 14.5 7.8 1.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM64160.1 - 0.048 14.1 0.2 0.048 14.1 0.2 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type BolA PF01722.18 KFM64160.1 - 0.048 13.9 1.0 0.26 11.6 1.0 1.9 1 1 0 1 1 1 0 BolA-like protein zf-C2H2_4 PF13894.6 KFM64160.1 - 0.17 12.8 19.4 0.4 11.6 0.4 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger Elf1 PF05129.13 KFM64160.1 - 0.32 11.1 9.9 0.45 10.6 0.5 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 KFM64161.1 - 8.1e-06 26.0 11.5 6.5e-05 23.2 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64161.1 - 0.063 13.8 0.3 0.063 13.8 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64161.1 - 0.34 11.9 15.4 0.69 10.9 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM64162.1 - 4.5e-07 30.0 5.8 0.00046 20.5 0.2 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM64162.1 - 9e-07 29.1 6.1 7.4e-05 23.0 0.7 2.5 2 1 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM64162.1 - 2.7e-05 24.6 4.3 0.004 17.9 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM64162.1 - 9e-05 22.7 5.7 0.11 12.9 1.4 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64162.1 - 0.00011 22.4 2.1 0.023 15.0 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM64162.1 - 0.0047 17.2 1.5 0.0093 16.2 1.5 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KFM64162.1 - 0.015 15.8 0.2 0.015 15.8 0.2 2.2 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Vps36-NZF-N PF16988.5 KFM64162.1 - 0.14 11.6 1.5 0.75 9.2 0.2 2.0 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_6 PF13912.6 KFM64162.1 - 0.14 12.2 0.6 0.14 12.2 0.6 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM64162.1 - 0.32 10.8 6.9 0.33 10.7 0.5 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFM64163.1 - 1.2e-05 25.5 8.5 1.2e-05 25.5 8.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM64163.1 - 0.00013 22.5 20.4 0.0074 17.0 7.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM64163.1 - 0.0011 19.3 22.5 0.081 13.4 7.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KFM64163.1 - 0.0013 19.0 10.9 0.0019 18.5 10.9 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFM64163.1 - 0.084 12.6 15.6 0.2 11.4 6.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Rad50_zn_hook PF04423.14 KFM64163.1 - 0.091 12.6 0.3 0.14 12.0 0.3 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif CpXC PF14353.6 KFM64163.1 - 1.8 8.6 5.0 5.7 7.0 0.7 2.2 1 1 1 2 2 2 0 CpXC protein zf-H2C2_2 PF13465.6 KFM64164.1 - 2.4e-09 37.2 14.0 1.4e-08 34.8 1.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64164.1 - 1.1e-08 35.1 14.8 3.2e-05 24.1 1.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64164.1 - 7.9e-06 26.3 12.2 0.00095 19.8 1.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM64164.1 - 4.2e-05 23.2 6.0 4.2e-05 23.2 6.0 2.5 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf-met PF12874.7 KFM64164.1 - 0.0066 16.8 13.0 0.13 12.7 0.9 3.2 3 1 1 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64164.1 - 0.012 15.8 16.4 0.036 14.4 1.9 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM64164.1 - 0.014 15.6 1.1 0.025 14.9 0.7 1.6 1 1 1 2 2 2 0 BolA-like protein zf-Di19 PF05605.12 KFM64164.1 - 0.028 14.7 6.8 0.51 10.7 0.9 2.3 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding OrsD PF12013.8 KFM64164.1 - 0.035 14.6 6.0 0.95 9.9 0.8 2.1 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-CHC2 PF01807.20 KFM64164.1 - 0.037 13.8 1.7 0.047 13.5 1.7 1.1 1 0 0 1 1 1 0 CHC2 zinc finger zf-C2H2_2 PF12756.7 KFM64164.1 - 0.17 12.2 8.7 0.57 10.5 0.9 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KFM64164.1 - 0.41 10.3 4.5 0.38 10.4 2.9 1.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain MAP65_ASE1 PF03999.12 KFM64165.1 - 5.7e-72 243.3 36.6 7e-72 243.0 36.6 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) MBD PF01429.19 KFM64166.1 - 1.8e-13 50.0 0.2 4.7e-13 48.6 0.2 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain HhH-GPD PF00730.25 KFM64166.1 - 9.4e-08 32.5 0.0 1.7e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Clr2_transil PF16761.5 KFM64166.1 - 0.23 12.3 2.0 0.42 11.5 0.1 2.4 3 0 0 3 3 3 0 Transcription-silencing protein, cryptic loci regulator Clr2 Proteasome PF00227.26 KFM64167.1 - 1.1e-29 103.3 0.0 1.3e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SRP19 PF01922.17 KFM64168.1 - 2.7e-27 95.6 0.1 3.6e-27 95.1 0.1 1.2 1 0 0 1 1 1 1 SRP19 protein Head_binding PF09008.10 KFM64168.1 - 0.027 14.7 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 Head binding DUF3370 PF11850.8 KFM64168.1 - 0.053 12.4 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) DDE_3 PF13358.6 KFM64170.1 - 0.058 13.2 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DciA PF05258.12 KFM64170.1 - 0.098 13.1 0.1 0.13 12.7 0.1 1.1 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA HEAT PF02985.22 KFM64172.1 - 0.0045 17.1 0.2 0.96 9.9 0.1 3.9 3 0 0 3 3 3 1 HEAT repeat GFD1 PF17331.2 KFM64172.1 - 0.24 11.7 1.3 0.54 10.5 1.3 1.6 1 0 0 1 1 1 0 GFD1 mRNA transport factor Ank_4 PF13637.6 KFM64174.1 - 9.8e-07 29.2 1.3 0.0035 17.9 0.2 1.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM64174.1 - 4.9e-06 27.0 0.0 8.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM64174.1 - 0.00073 19.8 0.1 0.0035 17.6 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM64174.1 - 0.00079 19.7 0.0 0.0058 17.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KFM64174.1 - 0.0019 18.6 0.1 0.0059 17.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat Myosin_N PF02736.19 KFM64176.1 - 0.0011 18.7 0.4 0.0014 18.4 0.4 1.1 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Cys_Met_Meta_PP PF01053.20 KFM64177.1 - 6.2e-06 25.0 0.0 6.2e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CR6_interact PF10147.9 KFM64180.1 - 1.1e-35 123.2 24.4 1.2e-35 123.1 23.8 1.3 1 1 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 FKBP_C PF00254.28 KFM64180.1 - 0.23 11.8 2.2 0.57 10.5 2.1 1.8 1 1 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_hydro_38 PF18438.1 KFM64180.1 - 0.74 9.9 9.2 0.23 11.6 0.9 2.9 2 1 1 3 3 3 0 Glycosyl hydrolases family 38 C-terminal domain 1 Dna2 PF08696.11 KFM64180.1 - 6.2 6.6 9.1 2.5 7.9 6.0 2.0 2 1 0 2 2 2 0 DNA replication factor Dna2 Aph-1 PF06105.12 KFM64181.1 - 1e-93 313.0 19.8 1.1e-93 312.9 19.8 1.0 1 0 0 1 1 1 1 Aph-1 protein YqfD PF06898.11 KFM64181.1 - 3.1 6.5 3.6 4.3 6.1 3.6 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Glyco_transf_10 PF00852.19 KFM64182.1 - 3.4e-60 202.8 0.0 4.8e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFM64182.1 - 5.3e-19 68.7 0.0 1.2e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal zf-H2C2_2 PF13465.6 KFM64184.1 - 2.2e-49 163.8 56.0 2.4e-09 37.2 1.0 9.1 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64184.1 - 8.2e-36 120.5 76.8 2.1e-05 24.7 2.9 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64184.1 - 3.5e-25 86.5 69.5 0.0045 17.7 1.8 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM64184.1 - 8.2e-23 80.1 62.3 0.00038 20.8 1.2 9.0 8 1 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64184.1 - 7.8e-12 45.2 49.6 0.0097 16.2 0.5 8.5 8 1 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM64184.1 - 8.1e-08 32.1 58.0 0.014 15.4 1.4 8.7 8 0 0 8 8 8 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM64184.1 - 9.3e-08 31.7 50.3 0.0067 16.2 1.5 8.3 8 0 0 8 8 8 6 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM64184.1 - 3e-05 24.0 23.9 0.3 11.2 0.0 7.0 4 3 3 7 7 7 3 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM64184.1 - 0.00012 22.2 26.6 0.13 12.4 3.5 4.0 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM64184.1 - 0.0025 17.9 32.3 7.6 6.7 0.1 7.9 8 0 0 8 8 8 1 DBF zinc finger BolA PF01722.18 KFM64184.1 - 0.017 15.4 15.0 1.9 8.8 0.6 5.2 1 1 4 5 5 5 0 BolA-like protein zf-C2H2_2 PF12756.7 KFM64184.1 - 0.019 15.3 59.5 0.64 10.4 2.0 7.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM64184.1 - 0.029 14.3 0.8 0.029 14.3 0.8 7.0 7 0 0 7 7 7 0 zinc-finger of a C2HC-type C1_1 PF00130.22 KFM64184.1 - 0.041 13.8 38.9 2.6 8.0 0.8 6.5 2 1 4 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YyzF PF14116.6 KFM64184.1 - 0.22 11.6 19.5 14 5.9 0.1 6.6 7 0 0 7 7 7 0 YyzF-like protein zf-C2H2_9 PF16293.5 KFM64184.1 - 0.25 11.2 34.6 6.3 6.7 0.2 7.7 3 2 5 8 8 8 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM64184.1 - 0.56 10.0 22.0 0.14 12.0 0.7 5.4 2 2 6 8 8 8 0 GAGA factor DUF5330 PF17264.2 KFM64184.1 - 0.84 9.7 4.4 98 3.1 0.0 4.3 4 0 0 4 4 4 0 Family of unknown function (DUF5330) zinc_ribbon_15 PF17032.5 KFM64184.1 - 3.7 8.4 27.2 3 8.6 1.4 4.2 1 1 3 4 4 4 0 zinc-ribbon family C5HCH PF17982.1 KFM64184.1 - 8.3 6.7 34.7 2 8.6 3.3 6.7 4 2 4 8 8 8 0 NSD Cys-His rich domain Tup_N PF08581.10 KFM64186.1 - 0.0026 18.0 11.4 0.0026 18.0 11.4 4.1 2 1 2 4 4 4 1 Tup N-terminal Cep57_CLD_2 PF14197.6 KFM64186.1 - 4.1 7.6 31.1 9.2 6.4 15.3 4.0 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Defensin_2 PF01097.18 KFM64187.1 - 9.9e-13 47.8 9.9 1.2e-12 47.5 9.9 1.1 1 0 0 1 1 1 1 Arthropod defensin Toxin_38 PF14866.6 KFM64187.1 - 4.6e-07 30.0 1.9 4.9e-07 29.9 1.9 1.1 1 0 0 1 1 1 1 Potassium channel toxin Gamma-thionin PF00304.20 KFM64187.1 - 0.0024 18.1 8.9 0.0029 17.8 8.9 1.1 1 0 0 1 1 1 1 Gamma-thionin family Toxin_2 PF00451.19 KFM64187.1 - 2 8.8 11.5 4 7.8 11.5 1.5 1 1 0 1 1 1 0 Scorpion short toxin, BmKK2 Ferritin PF00210.24 KFM64188.1 - 8.2e-40 136.0 2.4 9.7e-40 135.8 2.4 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KFM64188.1 - 0.0039 17.6 1.7 0.015 15.7 1.7 1.9 1 1 1 2 2 2 1 Rubrerythrin IcmF_C PF06744.12 KFM64188.1 - 0.045 13.4 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal DUF2150 PF09920.9 KFM64188.1 - 0.046 13.7 0.3 0.17 11.8 0.1 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) DUF4854 PF16146.5 KFM64188.1 - 0.083 13.2 1.3 0.84 10.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) TPR_2 PF07719.17 KFM64189.1 - 2.7e-08 33.3 0.0 0.0088 16.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM64189.1 - 6.1e-06 25.8 0.2 0.016 15.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM64189.1 - 3.3e-05 23.6 0.4 0.024 14.7 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM64189.1 - 0.0022 18.6 0.0 0.47 11.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM64189.1 - 0.0028 17.7 0.0 4.2 7.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM64189.1 - 0.0033 17.7 0.9 5.6 7.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.10 KFM64189.1 - 0.0062 15.6 0.5 0.026 13.5 0.5 1.8 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 KFM64189.1 - 0.007 16.6 1.0 6.8 7.1 0.0 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat UPF0242 PF06785.11 KFM64189.1 - 6.7 6.8 16.3 0.48 10.5 2.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Na_K-ATPase PF00287.18 KFM64190.1 - 4.8e-37 127.7 0.0 6.2e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain DDE_3 PF13358.6 KFM64192.1 - 2.3e-11 43.7 0.0 3.2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64192.1 - 2.7e-06 27.5 1.3 6e-06 26.4 1.3 1.6 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM64193.1 - 5.5e-16 58.6 3.5 6e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64193.1 - 1.4e-13 50.8 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64193.1 - 2.3e-07 30.5 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64193.1 - 0.0029 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64193.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ubiquitin PF00240.23 KFM64194.1 - 3.7e-19 68.2 0.2 6e-19 67.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KFM64194.1 - 8.8e-12 44.7 0.1 3.9e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 KFM64194.1 - 5.7e-06 26.1 0.7 9.8e-06 25.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFM64194.1 - 0.0022 18.4 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CUE PF02845.16 KFM64194.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 CUE domain Rad60-SLD_2 PF13881.6 KFM64194.1 - 0.068 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like zf-H2C2_2 PF13465.6 KFM64195.1 - 6.7e-72 234.9 89.3 1.7e-09 37.6 1.2 13.4 14 0 0 14 14 14 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64195.1 - 1.2e-45 151.5 111.2 8.9e-06 25.9 0.7 13.0 13 0 0 13 13 13 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64195.1 - 1.1e-30 103.6 102.1 0.0018 19.0 1.5 12.7 13 0 0 13 13 13 11 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM64195.1 - 3.7e-14 52.1 67.0 0.017 14.9 0.2 11.3 11 0 0 11 11 11 7 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM64195.1 - 7.5e-13 48.1 65.4 0.0074 16.3 1.0 12.6 12 0 0 12 12 12 8 C2H2-type zinc finger zf-met PF12874.7 KFM64195.1 - 9.6e-13 48.1 92.2 0.0013 19.0 1.4 12.9 13 0 0 13 13 13 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64195.1 - 2.6e-12 46.7 68.5 0.0021 18.3 0.3 12.3 12 1 1 13 13 13 8 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM64195.1 - 4.6e-05 23.6 12.1 5.7 7.3 0.1 6.4 1 1 5 6 6 6 3 BolA-like protein zf-C2HC_2 PF13913.6 KFM64195.1 - 0.00039 20.2 32.9 1.8 8.6 0.2 8.8 9 0 0 9 9 9 4 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM64195.1 - 0.21 12.4 57.0 0.73 10.6 1.0 7.0 1 1 5 7 7 7 0 zinc-ribbon family GASA PF02704.14 KFM64196.1 - 0.054 13.6 7.7 0.12 12.6 7.3 1.7 2 0 0 2 2 2 0 Gibberellin regulated protein DDE_3 PF13358.6 KFM64197.1 - 0.00022 21.0 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Tnp_P_element_C PF12596.8 KFM64198.1 - 0.003 18.1 0.0 0.0054 17.2 0.0 1.4 1 0 0 1 1 1 1 87kDa Transposase 7tm_1 PF00001.21 KFM64201.1 - 4e-28 98.5 4.7 5e-28 98.2 4.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM64201.1 - 6.8e-08 32.2 3.7 9e-08 31.8 3.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM64201.1 - 0.00013 21.7 5.3 0.00018 21.2 5.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFM64201.1 - 0.0015 18.4 3.5 0.0018 18.0 3.5 1.1 1 0 0 1 1 1 1 Olfactory receptor MarC PF01914.17 KFM64201.1 - 0.006 16.0 2.3 0.006 16.0 2.3 1.7 2 1 0 1 1 1 1 MarC family integral membrane protein 7TM_GPCR_Srw PF10324.9 KFM64201.1 - 0.014 14.7 9.5 0.022 14.0 9.5 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KFM64201.1 - 0.045 13.1 6.5 0.059 12.7 6.5 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv MMS1_N PF10433.9 KFM64202.1 - 2.7e-179 596.9 0.0 6.2e-179 595.7 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFM64202.1 - 6.4e-101 337.9 0.0 1.4e-99 333.5 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region B2-adapt-app_C PF09066.10 KFM64202.1 - 0.15 12.1 0.8 3.3 7.8 0.1 2.6 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain Pkinase_Tyr PF07714.17 KFM64204.1 - 7.5e-96 320.4 0.0 1.1e-95 319.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM64204.1 - 5.7e-43 147.2 0.0 8.5e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 KFM64204.1 - 4e-33 113.3 9.4 4.9e-11 42.5 0.4 4.8 4 0 0 4 4 4 4 IPT/TIG domain PSI PF01437.25 KFM64204.1 - 5.5e-06 26.8 12.1 1.4e-05 25.5 12.1 1.7 1 0 0 1 1 1 1 Plexin repeat Sema PF01403.19 KFM64204.1 - 5e-05 22.3 0.1 8.8e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 Sema domain Kinase-like PF14531.6 KFM64204.1 - 0.00026 20.4 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM64204.1 - 0.054 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain MIP PF00230.20 KFM64205.1 - 1.1e-69 234.6 8.0 1.4e-69 234.3 8.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Homeobox_KN PF05920.11 KFM64210.1 - 4.2e-06 26.6 0.6 6.6e-06 25.9 0.6 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFM64210.1 - 0.0019 18.0 0.2 0.0026 17.6 0.2 1.2 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFM64210.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF4679 PF15728.5 KFM64210.1 - 0.18 10.8 0.0 0.19 10.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) HTH_Tnp_Tc3_2 PF01498.18 KFM64211.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64211.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease TerY_C PF15616.6 KFM64212.1 - 0.15 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 TerY-C metal binding domain Ank_5 PF13857.6 KFM64213.1 - 3e-13 49.7 0.2 0.00014 22.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM64213.1 - 7.2e-12 45.7 0.1 1.1e-06 29.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFM64213.1 - 8.5e-10 38.6 5.6 0.00053 20.3 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KFM64213.1 - 7e-09 35.2 4.5 0.0096 16.4 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFM64213.1 - 7.6e-08 32.8 0.1 0.013 16.1 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) UPF0242 PF06785.11 KFM64213.1 - 0.086 12.9 1.0 0.16 12.1 1.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPR3 PF03666.13 KFM64213.1 - 0.13 11.0 5.4 0.19 10.5 5.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KFM64213.1 - 9.3 4.9 6.7 14 4.3 6.7 1.2 1 0 0 1 1 1 0 Presenilin ASCH PF04266.14 KFM64216.1 - 3.8e-14 53.2 0.0 1.3e-13 51.5 0.0 1.9 2 0 0 2 2 2 1 ASCH domain zf-C2HC5 PF06221.13 KFM64216.1 - 1.3e-09 37.9 12.2 2.6e-09 36.9 12.2 1.6 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type NCBP3 PF10309.9 KFM64219.1 - 3.3e-20 71.7 0.0 5.9e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KFM64219.1 - 0.00078 19.4 0.1 0.0049 16.9 0.1 2.2 1 1 0 1 1 1 1 RNA binding domain DUF4592 PF15262.6 KFM64219.1 - 5.1 7.8 9.5 0.36 11.5 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) Pkinase_Tyr PF07714.17 KFM64221.1 - 9.4e-54 182.4 0.9 1.3e-52 178.7 0.9 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM64221.1 - 2.3e-49 168.2 0.0 4e-49 167.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain PDZ PF00595.24 KFM64221.1 - 1.5e-10 41.2 0.3 2.7e-10 40.5 0.3 1.4 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 KFM64221.1 - 1.3e-08 34.9 1.5 1.3e-08 34.9 1.5 2.1 2 0 0 2 2 1 1 LIM domain PDZ_6 PF17820.1 KFM64221.1 - 4.5e-07 29.6 0.1 7.8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Kdo PF06293.14 KFM64221.1 - 1.4e-05 24.5 0.2 2.5e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM64221.1 - 0.00029 20.8 0.1 0.004 17.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM64221.1 - 0.00032 19.6 0.3 0.00043 19.2 0.3 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM64221.1 - 0.0018 17.7 0.0 0.1 11.9 0.1 2.3 2 0 0 2 2 2 1 Kinase-like PDZ_4 PF17816.1 KFM64221.1 - 0.03 14.7 0.3 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 PDZ domain RIO1 PF01163.22 KFM64221.1 - 0.037 13.6 0.2 0.067 12.8 0.2 1.4 1 0 0 1 1 1 0 RIO1 family Tricorn_PDZ PF14685.6 KFM64221.1 - 0.046 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain PDZ_2 PF13180.6 KFM64221.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Haspin_kinase PF12330.8 KFM64221.1 - 0.12 11.2 3.3 0.3 10.0 0.3 2.4 1 1 1 2 2 2 0 Haspin like kinase domain B2 PF11473.8 KFM64221.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA binding protein B2 DUF3970 PF13113.6 KFM64221.1 - 0.41 10.9 2.6 3.1 8.1 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) An_peroxidase PF03098.15 KFM64222.1 - 7.3e-145 483.5 0.0 9.4e-145 483.2 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Tox-GHH PF15636.6 KFM64225.1 - 4.6e-30 103.4 2.0 7.6e-30 102.7 0.4 2.1 2 0 0 2 2 2 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin RHS_repeat PF05593.14 KFM64225.1 - 4.4e-23 81.3 23.4 6.3e-08 33.0 0.0 10.6 11 0 0 11 11 11 6 RHS Repeat DUF4595 PF15283.6 KFM64225.1 - 0.046 13.8 20.6 0.52 10.4 1.8 6.5 3 3 1 5 5 5 0 Domain of unknown function (DUF4595) with porin-like fold GbpC PF08363.10 KFM64225.1 - 0.18 11.3 1.6 0.39 10.1 0.1 2.2 2 0 0 2 2 2 0 Glucan-binding protein C Ldl_recept_a PF00057.18 KFM64226.1 - 1.9e-06 28.0 6.9 1.9e-06 28.0 6.9 1.8 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Reprolysin PF01421.19 KFM64227.1 - 1.7e-22 80.3 0.0 3.2e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KFM64227.1 - 1.1e-14 54.9 0.7 2e-14 54.0 0.7 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFM64227.1 - 6.4e-13 49.3 0.0 1.3e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFM64227.1 - 2.2e-12 47.6 0.0 4.7e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFM64227.1 - 1.9e-11 44.2 0.0 4.3e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFM64227.1 - 4.7e-07 29.7 1.1 2.1e-06 27.5 1.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFM64227.1 - 0.0084 16.0 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Matrixin Astacin PF01400.24 KFM64227.1 - 0.026 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 KFM64227.1 - 0.069 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4953 PF16313.5 KFM64227.1 - 0.075 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Met-zincin BBS1 PF14779.6 KFM64227.1 - 0.084 12.3 0.7 8.4 5.8 0.3 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 HTH_Tnp_Tc3_2 PF01498.18 KFM64229.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64229.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64229.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64229.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64229.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64230.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64230.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_1 PF00515.28 KFM64232.1 - 9.4e-25 85.4 1.6 1.2e-08 34.4 0.0 3.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM64232.1 - 1e-17 62.7 0.9 6.7e-06 25.8 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM64232.1 - 6.2e-15 54.6 0.1 9.7e-09 34.8 0.0 3.2 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 KFM64232.1 - 1.8e-14 52.6 0.7 0.00011 22.2 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFM64232.1 - 4.2e-10 39.6 0.0 1.8e-05 24.8 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM64232.1 - 1e-07 31.8 2.8 0.0097 16.2 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM64232.1 - 1.3e-07 31.6 0.5 0.0018 18.3 0.1 3.2 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 KFM64232.1 - 1.8e-07 31.7 0.0 0.0013 19.3 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM64232.1 - 1.6e-05 25.3 0.2 0.0015 19.0 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM64232.1 - 0.00011 22.8 0.0 0.71 10.9 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM64232.1 - 0.00016 21.5 0.0 0.1 12.6 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM64232.1 - 0.00033 20.9 0.2 0.44 10.9 0.4 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM64232.1 - 0.047 14.3 2.4 0.47 11.2 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFM64232.1 - 0.047 13.7 1.8 2.2 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KFM64232.1 - 0.068 13.2 2.3 0.76 9.9 0.0 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Vasculin PF15337.6 KFM64233.1 - 6.5e-23 81.4 1.5 6.5e-23 81.4 1.5 2.1 1 1 1 2 2 2 1 Vascular protein family Vasculin-like 1 DUF4718 PF15842.5 KFM64233.1 - 0.0026 17.6 1.7 0.0032 17.3 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4718) G-patch_2 PF12656.7 KFM64233.1 - 0.089 12.9 0.8 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 G-patch domain YflT PF11181.8 KFM64233.1 - 0.32 11.5 3.3 0.14 12.7 0.7 1.8 2 1 0 2 2 2 0 Heat induced stress protein YflT RNase_Zc3h12a PF11977.8 KFM64234.1 - 1.3e-52 177.7 0.0 3.1e-52 176.5 0.0 1.7 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain SCRL PF06876.12 KFM64234.1 - 0.098 12.9 0.3 0.098 12.9 0.3 2.1 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein rve PF00665.26 KFM64235.1 - 8.5e-10 38.9 0.0 3.1e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 KFM64235.1 - 0.0031 17.3 0.0 0.0096 15.7 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KFM64238.1 - 2.7e-43 148.1 0.1 4.8e-43 147.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM64238.1 - 6e-19 68.0 0.0 1.9e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KFM64238.1 - 6.5e-12 45.8 0.4 1.6e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 RNase H DUF4817 PF16087.5 KFM64238.1 - 4.4e-06 26.4 0.0 1.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) Exo_endo_phos PF03372.23 KFM64238.1 - 3.5e-05 23.4 0.1 6.7e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.6 KFM64238.1 - 0.00092 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like HTH_32 PF13565.6 KFM64238.1 - 0.071 13.7 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 KFM64238.1 - 0.092 12.8 0.7 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix RVT_1 PF00078.27 KFM64239.1 - 7.5e-11 42.0 0.0 7.6e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_3 PF01381.22 KFM64240.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM64240.1 - 0.0083 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KFM64240.1 - 0.047 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 MarR family Apolipo_F PF15148.6 KFM64240.1 - 0.072 12.6 0.1 0.13 11.7 0.1 1.6 1 1 0 1 1 1 0 Apolipoprotein F HTH_Tnp_Tc3_2 PF01498.18 KFM64241.1 - 1.9e-19 69.7 3.6 6e-19 68.1 2.1 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64241.1 - 4.7e-16 58.8 0.0 2.4e-15 56.5 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM64241.1 - 2.1e-07 30.9 0.4 0.00015 21.8 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM64241.1 - 2.8e-07 31.0 4.4 3.8e-07 30.6 2.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64241.1 - 1e-06 28.7 2.3 8e-05 22.7 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64241.1 - 1.8e-06 27.6 3.3 2.6e-05 23.9 0.0 3.0 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM64241.1 - 2.6e-06 27.4 0.7 4.2e-05 23.5 0.1 2.6 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM64241.1 - 0.00014 21.6 0.8 0.0018 18.1 0.0 2.6 1 1 1 2 2 2 1 MarR family COMP PF11598.8 KFM64241.1 - 0.00099 19.5 2.3 0.0019 18.6 2.3 1.5 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein HTH_Crp_2 PF13545.6 KFM64241.1 - 0.0011 18.9 0.3 0.017 15.1 0.0 2.4 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM64241.1 - 0.024 14.3 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM64241.1 - 0.057 13.5 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM64241.1 - 0.098 12.9 0.1 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 KFM64241.1 - 0.19 11.9 0.0 31 4.7 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM64241.1 - 0.29 11.0 3.8 1.5 8.7 0.0 3.1 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM64241.1 - 1.1 8.8 3.6 7.5 6.1 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc3_2 PF01498.18 KFM64242.1 - 5.3e-16 58.6 3.5 6.1e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64242.1 - 1.4e-13 50.8 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64242.1 - 3.6e-06 26.7 0.8 1.7e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64242.1 - 0.0042 16.9 0.5 0.013 15.2 0.5 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64242.1 - 0.033 14.3 0.4 0.095 12.8 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM64242.1 - 8.2 7.1 14.2 0.13 12.9 2.0 3.0 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM64244.1 - 1.3e-73 248.4 0.0 1.8e-73 247.9 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 CAAP1 PF15335.6 KFM64244.1 - 0.14 12.7 0.2 0.35 11.5 0.2 1.7 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 EGF_CA PF07645.15 KFM64245.1 - 8.5e-08 32.3 10.2 8.5e-08 32.3 10.2 2.4 1 1 1 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 KFM64245.1 - 0.00031 20.9 17.3 0.00096 19.3 4.2 3.1 2 1 1 3 3 3 2 EGF domain DUF5348 PF17295.2 KFM64245.1 - 0.12 12.2 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) Nsp2a_N PF17896.1 KFM64246.1 - 0.085 12.0 0.0 0.095 11.9 0.0 1.3 1 1 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Pkinase PF00069.25 KFM64249.1 - 7.6e-29 100.9 0.0 7.6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM64249.1 - 2.5e-16 59.8 0.0 3e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM64249.1 - 0.072 12.0 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFM64249.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KFM64249.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KFM64250.1 - 0.05 12.9 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain HTH_Tnp_Tc3_2 PF01498.18 KFM64251.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64251.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64251.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64251.1 - 0.0023 17.7 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64251.1 - 1.8 9.2 15.7 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Pox_A11 PF05061.13 KFM64254.1 - 0.0056 16.0 0.2 0.0059 15.9 0.2 1.1 1 0 0 1 1 1 1 Poxvirus A11 Protein PKcGMP_CC PF16808.5 KFM64254.1 - 1.7 8.5 6.9 2.2 8.2 2.3 2.4 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_F11 PF04943.12 KFM64255.1 - 0.012 14.7 5.8 0.015 14.4 5.8 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein Beta_protein PF14350.6 KFM64255.1 - 0.023 14.1 0.8 0.026 13.9 0.8 1.1 1 0 0 1 1 1 0 Beta protein DNA_pol3_delta PF06144.13 KFM64255.1 - 0.031 14.1 5.3 0.055 13.3 5.1 1.6 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Nbl1_Borealin_N PF10444.9 KFM64255.1 - 0.04 13.6 0.9 0.04 13.6 0.9 2.1 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal DUF4460 PF14687.6 KFM64255.1 - 0.073 13.1 3.5 0.075 13.1 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4460) Lectin_N PF03954.14 KFM64255.1 - 0.076 12.8 3.8 0.2 11.4 3.8 1.8 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain TMCO5 PF14992.6 KFM64255.1 - 0.097 12.2 12.8 0.12 12.0 12.4 1.3 1 1 0 1 1 1 0 TMCO5 family YebO PF13974.6 KFM64255.1 - 0.13 12.4 8.9 0.34 11.0 6.9 2.6 2 1 0 2 2 2 0 YebO-like protein CLZ PF16526.5 KFM64255.1 - 0.13 12.7 6.6 0.3 11.5 6.6 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KIAA1430 PF13879.6 KFM64255.1 - 0.4 11.5 12.9 0.49 11.2 8.5 2.1 1 1 1 2 2 2 0 KIAA1430 homologue LMBR1 PF04791.16 KFM64255.1 - 1.5 7.6 5.8 2 7.2 5.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CREPT PF16566.5 KFM64255.1 - 3.3 7.9 13.3 0.94 9.6 10.3 1.6 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Guanylate_cyc PF00211.20 KFM64256.1 - 1.6e-28 99.6 0.0 1.8e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFM64257.1 - 1.5e-06 27.8 0.3 2e-06 27.4 0.3 1.2 1 0 0 1 1 1 1 Heme NO binding associated Pkinase_Tyr PF07714.17 KFM64257.1 - 6.2e-05 22.4 0.1 9.5e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ELMO_CED12 PF04727.13 KFM64257.1 - 0.047 13.8 0.2 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 ELMO/CED-12 family RRM_1 PF00076.22 KFM64258.1 - 1.9e-44 149.4 0.0 1.5e-11 44.0 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFM64258.1 - 0.085 12.9 0.0 1.6 8.9 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 NosL PF05573.12 KFM64258.1 - 0.22 11.9 0.2 0.47 10.8 0.2 1.5 1 0 0 1 1 1 0 NosL LRR_1 PF00560.33 KFM64259.1 - 0.0041 17.5 0.1 0.43 11.3 0.3 2.5 2 1 0 2 2 2 1 Leucine Rich Repeat LRR_8 PF13855.6 KFM64259.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeat DUF1489 PF07370.11 KFM64260.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1489) VPS9 PF02204.18 KFM64261.1 - 2.3e-21 75.9 0.7 2.7e-21 75.7 0.7 1.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MIT PF04212.18 KFM64262.1 - 0.00063 19.8 0.6 0.0011 18.9 0.1 1.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain HisKA PF00512.25 KFM64262.1 - 0.05 13.6 0.1 0.14 12.2 0.0 1.8 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain EGF_MSP1_1 PF12946.7 KFM64264.1 - 0.026 14.6 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 Neuralized PF07177.12 KFM64265.1 - 1.2e-79 265.5 0.0 1.9e-45 154.5 0.0 2.2 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.6 KFM64265.1 - 6.1e-14 51.6 14.6 1.1e-13 50.8 14.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM64265.1 - 6.9e-05 22.6 13.0 0.00014 21.6 13.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFM64265.1 - 0.002 18.0 17.6 0.0039 17.0 17.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2997 PF11211.8 KFM64265.1 - 0.087 12.6 0.0 2.3 8.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) DDE_3 PF13358.6 KFM64266.1 - 3.7e-13 49.5 0.0 5.3e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FYVE_2 PF02318.16 KFM64267.1 - 1.3e-06 28.6 8.9 2.3e-06 27.8 8.9 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 KFM64267.1 - 3.5 7.9 10.6 7.3 6.8 10.6 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger Peptidase_M13_N PF05649.13 KFM64269.1 - 3.5e-18 66.5 1.5 4.8e-18 66.0 0.9 1.4 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM64269.1 - 0.006 16.2 0.1 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M13 SipA_VBS PF17985.1 KFM64269.1 - 0.27 11.2 2.0 0.92 9.5 0.1 2.6 2 0 0 2 2 2 0 SipA vinculin binding site HTH_23 PF13384.6 KFM64270.1 - 0.0059 16.4 0.3 0.0072 16.1 0.3 1.2 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.18 KFM64270.1 - 0.0084 16.0 0.0 0.0089 15.9 0.0 1.0 1 0 0 1 1 1 1 'Paired box' domain MarR_2 PF12802.7 KFM64270.1 - 0.012 15.5 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 KFM64270.1 - 0.013 15.4 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain CALCOCO1 PF07888.11 KFM64270.1 - 0.062 12.2 0.0 0.066 12.1 0.0 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Sigma70_r4 PF04545.16 KFM64270.1 - 0.085 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Peptidase_M13_N PF05649.13 KFM64271.1 - 6.4e-46 157.8 0.5 7.5e-46 157.5 0.5 1.0 1 0 0 1 1 1 1 Peptidase family M13 RXT2_N PF08595.11 KFM64271.1 - 0.062 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal GyrB_insert PF18053.1 KFM64271.1 - 0.063 13.2 0.1 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain DUF1908 PF08926.11 KFM64272.1 - 2.6e-123 410.7 1.6 2.6e-123 410.7 1.6 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) DUF2294 PF10057.9 KFM64272.1 - 0.13 12.4 0.2 0.61 10.2 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) Pkinase PF00069.25 KFM64273.1 - 7e-09 35.4 0.2 7.3e-09 35.4 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM64273.1 - 3e-05 23.4 0.4 3e-05 23.4 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_20 PF00728.22 KFM64275.1 - 2.4e-12 46.9 0.0 4.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF4838 PF16126.5 KFM64275.1 - 0.039 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) BcrAD_BadFG PF01869.20 KFM64276.1 - 3.1e-19 69.5 0.0 3.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family MGC-24 PF05283.11 KFM64277.1 - 0.037 14.5 2.9 0.047 14.1 2.9 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HTH_Tnp_Tc3_2 PF01498.18 KFM64278.1 - 8.9e-16 57.9 6.5 1.6e-15 57.1 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64278.1 - 1.1e-15 57.7 0.1 1e-14 54.5 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64278.1 - 0.00067 20.2 1.5 0.00067 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM64278.1 - 0.0034 17.1 0.2 0.12 12.2 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64278.1 - 0.0067 16.5 0.2 0.025 14.7 0.2 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM64278.1 - 0.02 14.9 0.4 0.02 14.9 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix zf-H2C2_2 PF13465.6 KFM64279.1 - 3.2e-109 352.9 92.4 4.7e-10 39.4 0.3 15.1 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64279.1 - 1.3e-69 226.9 125.4 2e-05 24.8 2.5 14.1 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64279.1 - 4.5e-53 173.3 118.8 0.0002 21.9 0.5 14.1 14 0 0 14 14 14 14 C2H2-type zinc finger zf-met PF12874.7 KFM64279.1 - 1e-41 140.1 116.7 0.0016 18.7 1.3 14.3 14 0 0 14 14 14 14 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64279.1 - 6.4e-24 83.7 95.9 0.0078 16.5 0.4 14.4 14 0 0 14 14 14 12 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM64279.1 - 1.8e-23 81.9 86.9 0.03 14.1 0.7 14.5 14 0 0 14 14 14 11 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM64279.1 - 7.6e-19 67.2 89.6 0.0095 15.9 0.4 14.8 14 0 0 14 14 14 11 C2H2-type zinc finger GAGA PF09237.11 KFM64279.1 - 2.4e-07 30.4 43.2 1 9.2 0.0 11.5 2 1 12 14 14 14 4 GAGA factor BolA PF01722.18 KFM64279.1 - 2.5e-06 27.7 27.7 1.8 8.9 0.0 8.5 1 1 8 9 9 9 2 BolA-like protein Tox-HNH-HHH PF15637.6 KFM64279.1 - 1.2e-05 25.4 13.7 1.1 9.5 0.2 6.4 1 1 4 7 7 7 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2HC_2 PF13913.6 KFM64279.1 - 3.5e-05 23.6 61.5 5.2 7.1 0.0 13.5 14 0 0 14 14 14 1 zinc-finger of a C2HC-type DUF4825 PF16107.5 KFM64279.1 - 6.8e-05 22.9 0.0 0.46 10.6 0.0 4.7 3 2 2 5 5 5 1 Domain of unknown function (DUF4825) ADK_lid PF05191.14 KFM64279.1 - 8.2e-05 22.5 43.9 1.6 8.8 0.2 9.1 4 3 4 8 8 8 3 Adenylate kinase, active site lid DUF3396 PF11876.8 KFM64279.1 - 0.0026 17.3 0.0 38 3.7 0.0 4.9 3 3 3 6 6 6 0 Protein of unknown function (DUF3396) zf-Sec23_Sec24 PF04810.15 KFM64279.1 - 0.0033 17.4 61.0 1.8 8.7 1.2 12.7 10 2 3 13 13 13 2 Sec23/Sec24 zinc finger DUF952 PF06108.12 KFM64279.1 - 0.015 15.3 4.4 13 5.9 0.0 5.5 3 3 3 6 6 6 0 Protein of unknown function (DUF952) FYVE PF01363.21 KFM64279.1 - 0.023 14.8 7.8 0.023 14.8 7.8 7.4 2 1 4 6 6 5 0 FYVE zinc finger zf-DBF PF07535.12 KFM64279.1 - 0.039 14.0 66.1 19 5.4 0.1 13.5 14 0 0 14 14 14 0 DBF zinc finger NAD_kinase PF01513.21 KFM64279.1 - 0.1 11.7 0.5 33 3.5 0.1 4.2 1 1 1 2 2 2 0 ATP-NAD kinase zf_UBZ PF18439.1 KFM64279.1 - 0.14 11.8 69.0 5.1 6.8 0.7 13.3 14 0 0 14 14 13 0 Ubiquitin-Binding Zinc Finger KSHV_K1 PF11049.8 KFM64279.1 - 0.14 12.1 0.1 27 4.8 0.0 2.8 2 0 0 2 2 2 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus PqqA PF08042.11 KFM64279.1 - 1.2 9.3 8.8 5.3e+02 0.9 0.0 7.6 11 0 0 11 11 11 0 PqqA family zf-MYST PF17772.1 KFM64279.1 - 1.9 8.1 69.6 1.8 8.3 0.7 13.3 7 4 7 14 14 14 0 MYST family zinc finger domain zf-RRPl_C4 PF17026.5 KFM64279.1 - 2.8 8.1 58.1 0.56 10.3 8.1 6.0 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-H2C2_2 PF13465.6 KFM64280.1 - 1.7e-67 221.0 68.9 3.4e-08 33.6 0.7 11.1 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64280.1 - 7.4e-49 161.6 90.4 2.6e-05 24.4 1.3 10.4 10 1 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64280.1 - 4.2e-35 117.4 81.9 0.0022 18.7 1.7 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM64280.1 - 1.2e-26 92.2 85.2 5.5e-05 23.4 2.2 10.4 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64280.1 - 2.8e-19 68.9 66.5 0.0026 18.0 1.2 10.5 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM64280.1 - 1.8e-13 50.1 79.7 0.016 15.2 0.3 11.4 10 3 0 10 10 10 8 C2H2-type zinc finger ADK_lid PF05191.14 KFM64280.1 - 9e-08 32.0 28.4 0.22 11.5 2.1 6.1 4 2 3 7 7 7 6 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM64280.1 - 2.9e-07 30.2 36.7 2 8.4 0.1 10.3 10 0 0 10 10 10 3 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM64280.1 - 6.9e-05 22.9 45.5 0.56 10.4 0.2 9.7 10 0 0 10 10 10 3 DBF zinc finger DUF2256 PF10013.9 KFM64280.1 - 0.00012 22.1 32.6 16 5.7 0.1 9.9 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RRPl_C4 PF17026.5 KFM64280.1 - 0.00032 20.8 44.9 0.17 12.0 7.2 4.4 1 1 4 5 5 5 2 Putative ribonucleoprotein zinc-finger pf C4 type zf-Sec23_Sec24 PF04810.15 KFM64280.1 - 0.0012 18.9 39.6 1.2 9.2 1.9 9.7 6 3 4 10 10 10 1 Sec23/Sec24 zinc finger BolA PF01722.18 KFM64280.1 - 0.0016 18.6 22.3 0.22 11.8 0.2 5.8 1 1 5 6 6 6 1 BolA-like protein zf-CHCC PF10276.9 KFM64280.1 - 0.0025 17.8 14.1 28 4.9 0.0 8.3 10 0 0 10 10 10 0 Zinc-finger domain FYVE PF01363.21 KFM64280.1 - 0.0042 17.2 52.7 0.32 11.1 9.3 5.6 2 2 2 4 4 4 3 FYVE zinc finger C5HCH PF17982.1 KFM64280.1 - 0.015 15.4 48.9 3.7 7.8 2.3 9.7 4 2 6 10 10 10 0 NSD Cys-His rich domain Baculo_IE-1 PF05290.11 KFM64280.1 - 0.018 15.0 36.2 1.1 9.2 2.5 7.1 1 1 3 4 4 4 0 Baculovirus immediate-early protein (IE-0) HNH_5 PF14279.6 KFM64280.1 - 0.022 14.6 47.9 2.7 7.9 4.8 9.0 5 3 2 7 7 7 0 HNH endonuclease Zn-ribbon_8 PF09723.10 KFM64280.1 - 0.031 14.4 32.1 2.2 8.5 0.5 6.1 5 2 0 5 5 5 0 Zinc ribbon domain C1_1 PF00130.22 KFM64280.1 - 0.033 14.1 52.2 8.1 6.4 4.3 9.2 2 1 6 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFM64280.1 - 0.11 12.1 43.6 2.6 7.7 0.3 9.9 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KFM64280.1 - 0.12 13.2 41.8 0.58 10.9 2.5 5.5 1 1 5 6 6 6 0 zinc-ribbon family XPA_N PF01286.18 KFM64280.1 - 0.15 12.1 36.7 5.6 7.1 0.1 9.6 10 0 0 10 10 10 0 XPA protein N-terminal PqqA PF08042.11 KFM64280.1 - 0.22 11.6 1.1 3.1e+02 1.6 0.0 4.7 5 0 0 5 5 5 0 PqqA family zf-C2H2_3rep PF18868.1 KFM64280.1 - 0.3 11.8 40.6 3.9 8.2 1.9 6.7 3 3 2 6 6 6 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KFM64280.1 - 0.86 10.0 67.7 4.6 7.6 1.5 9.2 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) BHD_1 PF10403.9 KFM64280.1 - 1.2 9.0 7.2 94 3.0 0.0 5.0 5 1 0 5 5 5 0 Rad4 beta-hairpin domain 1 zf-C2H2_9 PF16293.5 KFM64280.1 - 1.5 8.7 46.0 11 5.9 0.5 9.6 3 3 7 10 10 10 0 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KFM64280.1 - 1.6 8.4 53.1 1.6 8.4 0.4 9.6 4 3 6 10 10 10 0 MYST family zinc finger domain GAGA PF09237.11 KFM64280.1 - 3.8 7.4 21.0 1.8 8.4 0.2 5.9 3 3 5 8 8 8 0 GAGA factor FYDLN_acid PF09538.10 KFM64280.1 - 9.9 6.9 22.2 60 4.4 0.1 7.0 3 1 5 8 8 7 0 Protein of unknown function (FYDLN_acid) DDE_3 PF13358.6 KFM64281.1 - 2.6e-16 59.7 0.1 2.8e-15 56.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64281.1 - 1.4e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64282.1 - 0.00017 21.4 0.0 0.00022 21.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease ABC_tran PF00005.27 KFM64283.1 - 3e-30 105.5 0.0 4.7e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM64283.1 - 4.7e-08 32.7 0.1 4.3e-05 23.1 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM64283.1 - 0.00099 19.0 0.3 0.017 15.0 0.2 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KFM64283.1 - 0.0046 17.1 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 KFM64283.1 - 0.011 15.8 0.3 0.028 14.5 0.3 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KFM64283.1 - 0.029 14.9 0.1 0.081 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFM64283.1 - 0.034 14.6 0.1 0.085 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KFM64283.1 - 0.038 13.7 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFM64283.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM64283.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF815 PF05673.13 KFM64283.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 KFM64283.1 - 0.16 11.9 0.1 0.88 9.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_membrane PF00664.23 KFM64287.1 - 8.6e-12 45.3 1.3 9.5e-12 45.1 1.3 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region PHC2_SAM_assoc PF16616.5 KFM64288.1 - 0.075 13.8 0.1 0.092 13.6 0.1 1.1 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Asp_Glu_race_2 PF14669.6 KFM64290.1 - 0.00096 18.8 0.0 0.0028 17.3 0.0 1.6 1 1 0 1 1 1 1 Putative aspartate racemase DUF5097 PF17020.5 KFM64290.1 - 0.032 14.6 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) PPR_2 PF13041.6 KFM64290.1 - 0.12 12.6 1.7 2.6 8.3 0.5 3.0 3 0 0 3 3 3 0 PPR repeat family ApoLp-III PF07464.11 KFM64290.1 - 0.23 11.5 0.3 0.44 10.6 0.3 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Defensin_like PF10868.8 KFM64291.1 - 3.4 8.5 10.3 0.13 13.1 1.7 2.7 2 0 0 2 2 2 0 Cysteine-rich antifungal protein 2, defensin-like DUF4808 PF16066.5 KFM64294.1 - 8.7e-13 48.9 0.0 1.2e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4808) RT_RNaseH_2 PF17919.1 KFM64297.1 - 1.3e-30 105.4 0.0 5.9e-30 103.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM64297.1 - 3.4e-29 101.2 0.0 1.6e-28 99.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotran_gag_2 PF14223.6 KFM64297.1 - 8e-29 100.1 7.5 8.6e-29 100.0 0.6 3.1 4 0 0 4 4 4 1 gag-polypeptide of LTR copia-type RVT_1 PF00078.27 KFM64297.1 - 2.3e-28 99.2 0.1 6.9e-28 97.7 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 KFM64297.1 - 2.9e-19 69.7 0.4 1.6e-18 67.3 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM64297.1 - 2.8e-18 66.2 0.0 4.4e-17 62.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM64297.1 - 2.4e-16 59.6 0.0 9.3e-16 57.7 0.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain Arc_C PF18162.1 KFM64297.1 - 4.7e-05 23.2 1.6 0.00016 21.5 0.4 2.6 3 0 0 3 3 3 1 Arc C-lobe zf-H2C2 PF09337.10 KFM64297.1 - 0.0017 18.5 0.0 0.0048 17.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM64297.1 - 0.28 11.5 0.0 0.28 11.5 0.0 4.0 4 0 0 4 4 4 0 Retrotransposon gag protein Pkinase PF00069.25 KFM64299.1 - 3.5e-33 115.1 0.0 5e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM64299.1 - 2e-31 109.2 0.0 3.8e-31 108.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM64299.1 - 1.8e-08 33.6 0.1 2.5e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM64299.1 - 9e-05 21.6 0.0 0.00012 21.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM64299.1 - 0.00032 20.1 0.1 0.00061 19.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFM64299.1 - 0.0011 18.4 0.1 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM64299.1 - 0.0055 16.7 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family CsgA PF17334.2 KFM64300.1 - 0.0094 16.7 1.6 0.11 13.2 0.2 3.1 3 1 1 4 4 4 1 Minor curli fiber component A HTH_Tnp_Tc3_2 PF01498.18 KFM64301.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64301.1 - 7.4e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Auts2 PF15336.6 KFM64303.1 - 9.4e-31 107.6 12.9 9.4e-31 107.6 12.9 6.6 4 2 2 6 6 6 1 Autism susceptibility gene 2 protein Arm PF00514.23 KFM64304.1 - 0.04 14.0 0.5 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Arc_C PF18162.1 KFM64306.1 - 2.1e-05 24.3 0.4 3.4e-05 23.6 0.4 1.3 1 0 0 1 1 1 1 Arc C-lobe Retrotrans_gag PF03732.17 KFM64306.1 - 0.00016 21.9 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 KFM64307.1 - 1.2e-30 105.5 0.0 3.3e-30 104.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM64307.1 - 4.2e-29 101.7 1.5 4.8e-29 101.5 0.3 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM64307.1 - 2.8e-27 95.1 0.0 1.4e-26 92.8 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM64307.1 - 1.5e-18 66.6 0.0 4e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM64307.1 - 8.1e-17 61.5 0.0 2.6e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFM64307.1 - 3e-06 27.3 0.4 7.1e-06 26.1 0.4 1.7 1 0 0 1 1 1 1 H2C2 zinc finger BH4 PF02180.17 KFM64307.1 - 0.045 13.6 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Bcl-2 homology region 4 DDE_Tnp_IS240 PF13610.6 KFM64307.1 - 0.15 12.2 3.3 0.16 12.2 0.2 2.6 2 0 0 2 2 2 0 DDE domain GSHPx PF00255.19 KFM64308.1 - 0.0019 17.7 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase zf-HIT PF04438.16 KFM64310.1 - 4.4e-10 39.2 8.9 7.8e-10 38.5 8.9 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF2870 PF11069.8 KFM64310.1 - 0.0059 17.0 1.8 0.0059 17.0 1.8 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2870) Zip PF02535.22 KFM64311.1 - 3.4e-56 190.9 2.9 5.2e-56 190.3 2.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1129 PF06570.11 KFM64311.1 - 0.29 10.6 6.5 0.24 10.9 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DDE_3 PF13358.6 KFM64315.1 - 3.6e-11 43.0 0.0 5.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64316.1 - 2.1e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64316.1 - 8.3e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64317.1 - 2.4e-16 59.7 2.2 4.4e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64317.1 - 9.4e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PDZ PF00595.24 KFM64318.1 - 2.3e-17 63.1 1.0 2.3e-17 63.1 1.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFM64318.1 - 6.5e-08 32.3 0.5 1.4e-07 31.3 0.1 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFM64318.1 - 4.1e-06 27.0 0.9 3.2e-05 24.2 0.2 2.0 2 0 0 2 2 2 1 PDZ domain DDE_3 PF13358.6 KFM64319.1 - 2.6e-14 53.2 0.0 4.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64319.1 - 1.3e-10 41.3 1.0 2.7e-10 40.4 1.0 1.6 1 0 0 1 1 1 1 Transposase FA_hydroxylase PF04116.13 KFM64321.1 - 1.5e-21 77.2 18.1 1.5e-21 77.2 18.1 2.2 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily Arteri_Gl PF00951.18 KFM64321.1 - 0.43 10.4 5.1 0.97 9.2 5.1 1.5 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein p450 PF00067.22 KFM64323.1 - 5.4e-64 216.6 0.0 6.2e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-H2C2_2 PF13465.6 KFM64324.1 - 2.5e-41 138.3 42.1 1.5e-07 31.5 1.8 8.0 9 0 0 9 9 8 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64324.1 - 1.2e-31 107.4 53.4 2.8e-06 27.5 1.5 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64324.1 - 2e-24 84.1 49.9 0.00021 21.9 1.1 7.3 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM64324.1 - 2.3e-13 50.1 42.1 0.00027 21.2 1.1 7.6 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM64324.1 - 5.3e-12 45.3 35.9 0.0086 15.8 1.3 7.4 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM64324.1 - 1.1e-09 38.3 32.7 0.007 16.6 0.7 6.7 7 0 0 7 7 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM64324.1 - 3.7e-07 30.0 38.5 0.022 14.7 0.8 6.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM64324.1 - 2.3e-05 24.1 40.7 0.66 9.8 1.2 7.2 7 0 0 7 7 7 5 zinc-finger C2H2-type DUF2256 PF10013.9 KFM64324.1 - 2.5e-05 24.3 17.9 4.6 7.4 0.0 6.6 7 0 0 7 7 7 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 KFM64324.1 - 8.5e-05 22.3 27.3 0.52 10.2 0.2 7.0 3 2 4 7 7 7 2 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM64324.1 - 9.8e-05 22.4 14.6 5.9 7.1 0.1 5.7 5 0 0 5 5 5 1 DBF zinc finger zf-C2HC_2 PF13913.6 KFM64324.1 - 0.0001 22.1 18.0 2 8.4 0.2 6.1 6 0 0 6 6 6 2 zinc-finger of a C2HC-type DZR PF12773.7 KFM64324.1 - 0.00011 22.1 12.3 0.16 12.0 0.4 4.1 2 1 1 3 3 3 1 Double zinc ribbon BolA PF01722.18 KFM64324.1 - 0.00025 21.2 8.5 2 8.7 0.2 5.4 1 1 3 4 4 4 1 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM64324.1 - 0.00053 20.0 18.8 1.5 8.9 0.0 6.6 5 2 2 7 7 7 2 Sec23/Sec24 zinc finger C1_1 PF00130.22 KFM64324.1 - 0.0021 17.9 25.7 0.77 9.7 1.2 5.6 3 1 3 6 6 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM64324.1 - 0.0033 17.2 13.9 2.8 7.8 0.1 5.8 2 1 5 7 7 7 1 GAGA factor ADK_lid PF05191.14 KFM64324.1 - 0.012 15.6 18.6 0.95 9.5 0.9 4.2 2 1 2 4 4 4 0 Adenylate kinase, active site lid C5HCH PF17982.1 KFM64324.1 - 0.017 15.3 11.6 8.3 6.7 0.2 5.3 5 0 0 5 5 5 0 NSD Cys-His rich domain zf-MYST PF17772.1 KFM64324.1 - 0.034 13.7 29.6 1.3 8.6 0.0 6.9 4 1 3 7 7 7 0 MYST family zinc finger domain ZapC PF07126.12 KFM64324.1 - 0.1 12.2 2.4 8.2 6.0 0.0 3.2 1 1 1 3 3 3 0 Cell-division protein ZapC zf-C2H2_2 PF12756.7 KFM64324.1 - 0.15 12.4 41.3 0.71 10.2 0.8 6.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM64324.1 - 0.3 11.2 25.0 0.11 12.6 5.9 3.7 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type YyzF PF14116.6 KFM64324.1 - 0.33 11.0 12.8 23 5.1 0.1 5.4 6 0 0 6 6 6 0 YyzF-like protein C1_4 PF07975.12 KFM64324.1 - 0.52 10.6 24.3 3.3 8.0 2.6 4.5 2 1 3 5 5 5 0 TFIIH C1-like domain zinc_ribbon_15 PF17032.5 KFM64324.1 - 0.69 10.7 21.5 8.5 7.2 1.8 3.9 1 1 0 3 3 3 0 zinc-ribbon family DUF2039 PF10217.9 KFM64324.1 - 1.7 9.1 22.6 0.45 10.9 6.0 3.6 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2039) zf-HIT PF04438.16 KFM64324.1 - 2.8 7.9 24.1 34 4.4 0.3 6.3 6 0 0 6 6 6 0 HIT zinc finger DDE_Tnp_IS1595 PF12762.7 KFM64325.1 - 1.4e-08 34.9 0.0 1.4e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain COOH-NH2_lig PF14395.6 KFM64325.1 - 0.18 11.0 0.0 0.18 11.0 0.0 1.0 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 zf-H2C2_2 PF13465.6 KFM64326.1 - 1.4e-51 170.7 61.6 1.2e-08 35.0 1.9 10.2 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64326.1 - 8.4e-39 129.9 83.4 5.8e-05 23.3 1.5 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64326.1 - 4.4e-30 101.8 77.7 0.00041 21.0 0.7 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM64326.1 - 7.9e-29 99.2 71.2 2.5e-05 24.5 0.8 9.2 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64326.1 - 8.2e-16 57.8 52.1 0.025 14.9 0.1 9.5 9 1 1 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM64326.1 - 1.1e-10 41.1 45.6 0.025 14.3 0.3 9.1 9 1 0 9 9 9 5 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM64326.1 - 1.7e-06 27.7 55.2 0.00011 21.9 2.0 8.6 9 0 0 9 9 9 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM64326.1 - 0.00012 22.0 66.7 0.86 9.7 0.8 9.7 9 1 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM64326.1 - 0.0013 18.5 42.0 1.8 8.5 0.4 8.8 2 2 7 9 9 9 3 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM64326.1 - 0.0023 18.2 15.6 1.9 8.8 0.5 5.5 1 1 5 6 6 6 2 BolA-like protein zf-RRPl_C4 PF17026.5 KFM64326.1 - 0.0028 17.7 37.8 0.12 12.4 7.7 4.3 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-Sec23_Sec24 PF04810.15 KFM64326.1 - 0.0046 17.0 31.1 2.3 8.3 0.5 7.7 6 2 2 8 8 8 2 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM64326.1 - 0.014 15.2 23.7 0.12 12.2 0.6 6.5 2 1 5 7 7 7 0 GAGA factor zf-C2HC_2 PF13913.6 KFM64326.1 - 0.029 14.3 32.2 3 7.8 0.3 8.2 9 1 0 9 9 9 0 zinc-finger of a C2HC-type Mga PF05043.13 KFM64326.1 - 0.037 14.6 2.4 11 6.6 0.2 3.4 2 2 0 2 2 2 0 Mga helix-turn-helix domain FYVE PF01363.21 KFM64326.1 - 0.24 11.6 46.5 0.13 12.4 10.7 5.2 1 1 2 3 3 2 0 FYVE zinc finger zf-DBF PF07535.12 KFM64326.1 - 0.35 11.0 44.4 5.6 7.2 0.1 8.8 8 1 1 9 9 9 0 DBF zinc finger TRAF6_Z2 PF18048.1 KFM64326.1 - 0.38 10.9 39.4 0.31 11.2 3.2 7.6 8 0 0 8 8 8 0 TNF receptor-associated factor 6 zinc finger 2 PqqA PF08042.11 KFM64326.1 - 0.83 9.8 2.0 3.5e+02 1.4 0.0 4.2 5 0 0 5 5 5 0 PqqA family DUF2039 PF10217.9 KFM64326.1 - 0.89 9.9 35.7 0.37 11.1 6.4 4.5 1 1 4 5 5 5 0 Uncharacterized conserved protein (DUF2039) DUF5330 PF17264.2 KFM64326.1 - 2.4 8.3 13.5 59 3.8 0.0 6.0 6 0 0 6 6 6 0 Family of unknown function (DUF5330) zf-C2H2_2 PF12756.7 KFM64326.1 - 3.3 8.1 64.0 0.73 10.2 0.9 7.9 1 1 5 7 7 6 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM64326.1 - 6.9 7.5 38.4 1 10.1 1.9 5.1 1 1 5 6 6 6 0 zinc-ribbon family zf-C2H2 PF00096.26 KFM64327.1 - 5.4e-12 45.5 10.7 1e-05 25.7 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM64327.1 - 1.4e-10 41.1 9.3 4.4e-08 33.2 0.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM64327.1 - 2.7e-08 34.0 10.0 0.00088 19.9 3.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM64327.1 - 5.4e-07 29.8 10.3 0.0041 17.5 2.9 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM64327.1 - 5.2e-06 26.1 5.4 0.0056 16.4 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM64327.1 - 8e-05 22.8 9.4 0.045 14.1 2.2 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM64327.1 - 0.00079 19.4 10.7 0.11 12.5 4.2 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM64327.1 - 0.0014 18.5 2.6 0.2 11.5 0.3 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM64327.1 - 0.002 18.2 3.6 0.74 10.0 0.5 2.3 2 0 0 2 2 2 2 DBF zinc finger DUF2256 PF10013.9 KFM64327.1 - 0.0025 17.9 1.0 1.2 9.4 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) TRAF6_Z2 PF18048.1 KFM64327.1 - 0.016 15.3 7.2 0.15 12.2 0.3 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 HNH_5 PF14279.6 KFM64327.1 - 0.018 14.9 1.5 1.5 8.7 1.4 2.1 1 1 1 2 2 2 0 HNH endonuclease zf-C2H2_11 PF16622.5 KFM64327.1 - 0.019 14.7 4.1 0.21 11.4 0.3 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM64327.1 - 0.02 14.8 5.7 0.31 11.0 0.8 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM64327.1 - 0.025 14.7 3.2 0.028 14.5 3.2 1.1 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-MYST PF17772.1 KFM64327.1 - 0.032 13.8 4.3 0.21 11.3 0.7 2.0 1 1 1 2 2 2 0 MYST family zinc finger domain BolA PF01722.18 KFM64327.1 - 0.033 14.5 0.5 0.18 12.1 0.5 1.8 1 1 0 1 1 1 0 BolA-like protein C5HCH PF17982.1 KFM64327.1 - 0.038 14.2 4.4 0.42 10.8 0.6 2.1 1 1 1 2 2 2 0 NSD Cys-His rich domain DUF2757 PF10955.8 KFM64327.1 - 0.046 14.0 2.7 1.7 9.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) Prok-RING_1 PF14446.6 KFM64327.1 - 0.062 13.2 2.6 3.9 7.5 0.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 KFM64327.1 - 0.091 12.8 2.6 2.8 8.0 0.4 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM64327.1 - 0.093 13.1 7.7 0.37 11.1 2.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) LIM PF00412.22 KFM64327.1 - 0.16 12.2 5.0 11 6.3 0.3 2.1 1 1 0 1 1 1 0 LIM domain Baculo_IE-1 PF05290.11 KFM64327.1 - 0.24 11.3 4.0 2.3 8.2 0.3 2.0 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) Zn-C2H2_12 PF18112.1 KFM64327.1 - 0.29 11.7 7.0 3.7 8.1 0.3 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-HIT PF04438.16 KFM64327.1 - 0.4 10.6 4.1 2.7 7.9 0.4 2.1 2 0 0 2 2 2 0 HIT zinc finger FYVE PF01363.21 KFM64327.1 - 0.43 10.8 5.6 1.3 9.2 5.6 1.7 1 1 0 1 1 1 0 FYVE zinc finger Vps39_2 PF10367.9 KFM64327.1 - 0.57 10.7 7.0 3.5 8.1 1.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-BED PF02892.15 KFM64327.1 - 1 9.5 8.7 7.5 6.7 0.9 2.1 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KFM64328.1 - 0.00079 19.7 10.5 0.035 14.5 0.5 3.5 3 1 0 3 3 3 2 Zinc-finger double domain zf-C4_ClpX PF06689.13 KFM64328.1 - 0.028 14.3 1.0 0.031 14.2 0.1 1.5 2 0 0 2 2 2 0 ClpX C4-type zinc finger CwfJ_C_1 PF04677.15 KFM64328.1 - 0.046 13.6 1.8 0.63 9.9 0.2 2.1 1 1 1 2 2 2 0 Protein similar to CwfJ C-terminus 1 zf-C2H2_4 PF13894.6 KFM64328.1 - 0.33 11.9 10.2 4.6 8.3 1.0 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM64328.1 - 3 8.5 15.5 9.8 6.9 3.5 3.8 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM64328.1 - 4.8 7.0 14.4 1.1 9.1 4.0 3.4 3 1 0 3 3 3 0 C2H2-type zinc-finger domain THAP PF05485.12 KFM64331.1 - 1.9e-05 25.5 0.1 2.1e-05 25.3 0.1 1.0 1 0 0 1 1 1 1 THAP domain Astacin PF01400.24 KFM64332.1 - 2.2e-53 180.8 0.0 2.7e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFM64332.1 - 0.0035 16.4 0.1 0.0052 15.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 KFM64332.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 KFM64332.1 - 0.13 12.8 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFM64332.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DDE_1 PF03184.19 KFM64333.1 - 2.2e-31 108.9 0.5 3.3e-31 108.3 0.5 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Capsid_N PF16903.5 KFM64333.1 - 0.012 15.2 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Major capsid protein N-terminus Astacin PF01400.24 KFM64334.1 - 1e-51 175.3 0.0 1.3e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM64334.1 - 0.001 18.9 0.2 0.021 14.7 0.1 2.2 1 1 1 2 2 2 1 Matrixin Peptidase_M66 PF10462.9 KFM64334.1 - 0.0084 15.1 0.2 0.012 14.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 KFM64334.1 - 0.066 13.7 0.1 0.097 13.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 KFM64334.1 - 0.13 10.9 0.1 0.19 10.3 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family DUF682 PF05081.12 KFM64334.1 - 0.18 11.6 0.2 0.3 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF682) Reprolysin_4 PF13583.6 KFM64334.1 - 0.21 11.2 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like TT1725 PF18324.1 KFM64337.1 - 0.049 13.7 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 Hypothetical protein TT1725 HTH_Tnp_Tc3_2 PF01498.18 KFM64338.1 - 5.7e-33 113.0 4.2 1.6e-15 57.1 0.3 2.3 2 0 0 2 2 2 2 Transposase HTH_32 PF13565.6 KFM64338.1 - 7.4e-11 42.5 17.3 7.8e-06 26.4 0.7 3.7 4 0 0 4 4 4 2 Homeodomain-like domain FUR PF01475.19 KFM64338.1 - 2.1e-07 31.1 0.0 0.031 14.4 0.0 2.3 2 0 0 2 2 2 2 Ferric uptake regulator family HTH_Crp_2 PF13545.6 KFM64338.1 - 0.00016 21.6 4.8 0.83 9.7 0.0 4.1 4 0 0 4 4 4 2 Crp-like helix-turn-helix domain HTH_33 PF13592.6 KFM64338.1 - 0.00059 19.4 1.8 1.1 8.9 0.1 2.8 2 0 0 2 2 2 2 Winged helix-turn helix HTH_7 PF02796.15 KFM64338.1 - 0.0028 17.7 4.3 2.3 8.4 0.3 3.6 4 0 0 4 4 4 2 Helix-turn-helix domain of resolvase MarR_2 PF12802.7 KFM64338.1 - 0.0059 16.5 0.5 9.7 6.2 0.0 3.7 2 2 2 4 4 4 2 MarR family HTH_3 PF01381.22 KFM64338.1 - 0.0091 16.0 0.9 54 3.9 0.0 4.2 4 0 0 4 4 4 0 Helix-turn-helix HTH_21 PF13276.6 KFM64338.1 - 0.047 13.8 0.0 21 5.3 0.0 2.8 2 0 0 2 2 2 0 HTH-like domain Phage_CII PF05269.11 KFM64338.1 - 0.053 13.7 0.1 6.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage CII protein Flexi_CP_N PF08358.10 KFM64338.1 - 0.14 12.1 0.1 40 4.3 0.0 3.0 4 0 0 4 4 4 0 Carlavirus coat HTH_30 PF13556.6 KFM64338.1 - 0.15 11.9 2.8 14 5.6 0.2 2.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_22 PF13309.6 KFM64338.1 - 0.18 11.9 0.2 28 4.9 0.0 2.4 2 0 0 2 2 2 0 HTH domain HTH_8 PF02954.19 KFM64338.1 - 0.23 11.3 1.4 25 4.8 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Med1 PF10744.9 KFM64339.1 - 2.1e-11 43.5 0.7 2.2e-11 43.4 0.7 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 LIP1 PF15904.5 KFM64339.1 - 0.031 14.6 0.1 0.033 14.5 0.1 1.0 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 Glyco_hydro_18 PF00704.28 KFM64340.1 - 3.4e-89 299.7 0.4 4.1e-89 299.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 KFM64340.1 - 1.5e-08 34.6 0.7 3e-08 33.7 0.7 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Costars PF14705.6 KFM64341.1 - 9.9e-32 109.0 0.0 1.3e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Costars FNIP_M PF14637.6 KFM64342.1 - 1.4e-73 247.6 0.4 2.2e-73 247.0 0.4 1.3 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 KFM64342.1 - 3.1e-51 173.7 0.1 6.7e-51 172.6 0.1 1.6 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 KFM64342.1 - 1.3e-16 62.0 4.2 2.1e-14 54.8 1.0 3.7 2 1 0 2 2 2 1 Folliculin-interacting protein N-terminus DUF4371 PF14291.6 KFM64343.1 - 3.8e-10 39.8 0.0 6.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) PepX_C PF08530.10 KFM64343.1 - 0.22 11.5 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Mob1_phocein PF03637.17 KFM64344.1 - 3.5e-84 280.9 0.1 4.3e-84 280.7 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family Actin PF00022.19 KFM64345.1 - 7.8e-09 34.6 0.0 8.1e-09 34.6 0.0 1.0 1 0 0 1 1 1 1 Actin Cyclin_N PF00134.23 KFM64346.1 - 3.5e-32 110.8 3.1 5.6e-32 110.2 1.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFM64346.1 - 9.5e-11 41.8 2.9 2.1e-10 40.7 0.9 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM64347.1 - 5.3e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64347.1 - 2.7e-13 49.9 0.0 4.6e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64347.1 - 2.3e-07 30.4 1.1 7.3e-07 28.9 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64347.1 - 0.0027 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64347.1 - 2.2 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Bys1 PF04681.12 KFM64348.1 - 0.13 12.2 2.0 2 8.3 0.0 2.3 1 1 1 2 2 2 0 Blastomyces yeast-phase-specific protein WD40 PF00400.32 KFM64349.1 - 8.1e-13 48.6 0.6 3.8e-06 27.5 0.1 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM64349.1 - 4.2e-05 23.8 0.0 0.67 10.3 0.0 2.8 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM64349.1 - 0.00066 18.5 1.0 0.026 13.2 1.0 2.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KFM64349.1 - 0.032 13.6 0.1 0.062 12.6 0.1 1.4 1 0 0 1 1 1 0 WD40-like domain WD40 PF00400.32 KFM64350.1 - 2.1e-06 28.4 2.4 0.011 16.5 0.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KFM64350.1 - 0.063 13.8 0.0 2.9 8.5 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain Hira PF07569.11 KFM64350.1 - 0.16 11.7 0.1 0.4 10.4 0.0 1.6 2 0 0 2 2 2 0 TUP1-like enhancer of split Nup160 PF11715.8 KFM64350.1 - 0.21 10.2 0.3 18 3.8 0.8 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.32 KFM64351.1 - 1.7e-10 41.3 5.2 3e-06 27.8 0.3 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat eIF2A PF08662.11 KFM64351.1 - 3.2e-05 23.9 0.1 0.086 12.7 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFM64351.1 - 0.0055 17.0 0.9 0.015 15.5 0.1 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 KFM64351.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 HELP motif TgMIC1 PF11476.8 KFM64351.1 - 0.095 12.4 0.4 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Bac_DnaA_C PF08299.11 KFM64354.1 - 0.037 14.1 0.0 0.037 14.1 0.0 1.0 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix CP2 PF04516.15 KFM64355.1 - 2.4e-27 95.7 0.1 3.5e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFM64355.1 - 1e-20 73.3 0.0 1.9e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CP2 PF04516.15 KFM64356.1 - 1.1e-22 80.5 0.0 1.6e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor SAM_1 PF00536.30 KFM64357.1 - 1.1e-09 38.5 0.8 1.9e-09 37.8 0.2 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM64357.1 - 2.4e-06 27.6 0.3 2.5e-05 24.3 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PHAT PF09246.10 KFM64357.1 - 0.0013 18.6 0.0 1.1 9.1 0.0 2.8 3 0 0 3 3 3 2 PHAT DUF4508 PF14969.6 KFM64357.1 - 0.043 14.1 0.2 0.11 12.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Peptidase_A17 PF05380.13 KFM64358.1 - 3.5e-40 137.6 0.2 5.5e-40 137.0 0.2 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase rve PF00665.26 KFM64358.1 - 0.00047 20.3 0.1 0.00094 19.4 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM64358.1 - 0.013 15.6 0.4 0.027 14.6 0.4 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain DUF1759 PF03564.15 KFM64359.1 - 4.3e-14 52.7 0.1 1e-13 51.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM64359.1 - 0.0038 17.0 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DDE_3 PF13358.6 KFM64360.1 - 1.6e-10 41.0 0.0 1.7e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HPD PF05044.12 KFM64362.1 - 2.3e-77 258.2 5.6 3.3e-77 257.7 5.6 1.2 1 0 0 1 1 1 1 Homeo-prospero domain IGFL PF14653.6 KFM64362.1 - 0.058 13.4 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Insulin growth factor-like family zf-CCHH PF10283.9 KFM64363.1 - 2.2e-20 72.3 19.2 5e-10 39.2 7.2 2.4 2 0 0 2 2 2 2 PBZ domain FHA_2 PF17913.1 KFM64363.1 - 1.1e-06 28.7 0.0 3.4e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain FHA PF00498.26 KFM64363.1 - 0.00037 20.8 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain Glyco_hydro_35 PF01301.19 KFM64367.1 - 7.2e-99 331.4 0.0 1.1e-98 330.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KFM64367.1 - 1.9e-07 30.8 0.0 9.2e-07 28.5 0.0 2.1 2 1 0 2 2 2 1 Beta-galactosidase DUF3498 PF12004.8 KFM64368.1 - 1.2e-57 196.3 23.7 1.2e-57 196.3 23.7 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF3498) RasGAP PF00616.19 KFM64368.1 - 2.1e-15 57.0 0.5 2.1e-15 57.0 0.5 3.1 2 2 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Rx_N PF18052.1 KFM64368.1 - 0.0076 16.5 1.0 0.0076 16.5 1.0 2.7 3 1 0 3 3 3 1 Rx N-terminal domain Lant_dehydr_C PF14028.6 KFM64368.1 - 0.11 12.1 1.4 0.19 11.2 1.4 1.4 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term WXG100 PF06013.12 KFM64368.1 - 0.12 12.6 0.2 0.12 12.6 0.2 3.6 3 1 1 4 4 4 0 Proteins of 100 residues with WXG bZIP_1 PF00170.21 KFM64368.1 - 0.21 11.7 11.6 1.2 9.3 0.8 2.9 2 0 0 2 2 2 0 bZIP transcription factor Med9 PF07544.13 KFM64368.1 - 0.74 9.9 13.9 1.8 8.7 4.9 2.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Med4 PF10018.9 KFM64368.1 - 1.9 8.1 15.6 0.2 11.3 4.8 3.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 C2 PF00168.30 KFM64369.1 - 9.1e-12 45.2 0.0 1.6e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KFM64369.1 - 0.0045 17.5 1.1 0.016 15.7 0.1 2.5 2 1 0 2 2 2 1 PH domain HTH_Tnp_Tc3_2 PF01498.18 KFM64370.1 - 7.3e-16 58.2 6.5 1.7e-15 57.0 6.5 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64370.1 - 1.2e-15 57.6 0.2 1.3e-14 54.2 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64370.1 - 0.00082 19.9 1.5 0.00082 19.9 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM64370.1 - 0.003 17.3 0.1 0.13 12.1 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64370.1 - 0.018 15.1 0.1 0.073 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM64370.1 - 0.039 14.0 0.4 0.039 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM64373.1 - 2e-16 59.9 3.2 4.2e-16 58.9 3.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64373.1 - 1.5e-14 53.9 0.0 2.6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64373.1 - 2.1e-06 28.2 5.0 1.4e-05 25.6 1.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM64373.1 - 0.0016 18.4 0.9 0.028 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 KFM64373.1 - 0.0031 17.6 1.5 0.3 11.3 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64373.1 - 0.0043 16.8 2.0 0.28 11.0 0.1 3.0 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM64373.1 - 0.006 16.5 1.1 0.034 14.0 0.0 2.5 2 1 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM64373.1 - 0.011 15.7 1.0 0.071 13.1 0.1 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain PAX PF00292.18 KFM64373.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain HTH_24 PF13412.6 KFM64373.1 - 0.26 10.9 1.6 2.4 7.8 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 KFM64373.1 - 0.36 10.4 2.1 0.37 10.3 0.1 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 DDE_3 PF13358.6 KFM64374.1 - 6.5e-11 42.2 0.2 2.6e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease 7tm_2 PF00002.24 KFM64375.1 - 6.1e-25 87.9 25.2 9.1e-25 87.4 25.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 KFM64375.1 - 0.0082 16.5 8.5 0.035 14.5 8.5 2.1 1 0 0 1 1 1 1 Somatomedin B domain DUF3566 PF12089.8 KFM64375.1 - 2.9 8.3 12.6 7.1 7.0 1.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) HTH_Tnp_Tc3_2 PF01498.18 KFM64376.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64376.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Collagen PF01391.18 KFM64377.1 - 8.9e-63 207.9 206.4 3.4e-10 39.5 29.1 9.1 2 2 6 8 8 8 8 Collagen triple helix repeat (20 copies) Terpene_synth PF01397.21 KFM64378.1 - 0.0089 15.7 0.1 0.0089 15.7 0.1 1.0 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain Guanylate_cyc PF00211.20 KFM64381.1 - 2.1e-65 219.8 0.0 3.1e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HTH_Tnp_Tc3_2 PF01498.18 KFM64382.1 - 5.2e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64382.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64382.1 - 2.2e-07 30.5 1.2 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64382.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64382.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Pkinase_Tyr PF07714.17 KFM64383.1 - 1.2e-21 77.2 0.0 1.5e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM64383.1 - 3e-15 56.3 0.0 3.8e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3336 PF11815.8 KFM64383.1 - 0.13 12.0 0.2 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) I-set PF07679.16 KFM64384.1 - 1.3e-25 89.2 0.0 2.1e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM64384.1 - 1.4e-23 83.3 0.2 1.6e-11 44.7 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM64384.1 - 7.8e-21 74.1 0.1 3.4e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM64384.1 - 1.1e-17 64.2 0.1 1e-07 32.1 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain PLAC PF08686.11 KFM64384.1 - 3.6e-10 40.4 9.2 5.9e-10 39.7 9.2 1.3 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain V-set PF07686.17 KFM64384.1 - 2.1e-07 31.1 2.5 0.06 13.5 0.0 3.5 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM64384.1 - 4.4e-05 23.7 0.3 0.23 11.7 0.0 2.9 2 1 1 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFM64384.1 - 0.00026 20.5 2.6 0.2 11.3 0.0 2.6 3 0 0 3 3 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFM64384.1 - 0.0023 17.9 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM64384.1 - 0.049 13.7 0.0 14 5.8 0.0 2.3 2 0 0 2 2 2 0 C17orf99 Ig domain Crisp PF08562.10 KFM64384.1 - 0.056 14.0 6.1 0.13 12.9 6.1 1.5 1 0 0 1 1 1 0 Crisp Integrase_H2C2 PF17921.1 KFM64385.1 - 6.1e-13 48.7 0.7 6.9e-13 48.5 0.7 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM64385.1 - 3.5e-06 27.1 0.3 4.4e-06 26.8 0.3 1.1 1 0 0 1 1 1 1 H2C2 zinc finger Spectrin PF00435.21 KFM64386.1 - 0 1410.2 243.5 3.3e-27 95.0 6.8 22.9 23 0 0 23 23 23 22 Spectrin repeat EFhand_Ca_insen PF08726.10 KFM64386.1 - 1e-26 92.8 1.0 1.2e-25 89.3 0.1 3.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand SH3_1 PF00018.28 KFM64386.1 - 7.5e-14 51.1 0.0 1.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain EF-hand_1 PF00036.32 KFM64386.1 - 1.3e-10 40.1 0.1 0.00072 18.9 0.0 3.2 2 0 0 2 2 2 2 EF hand SH3_9 PF14604.6 KFM64386.1 - 2.5e-09 36.9 0.0 5.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_7 PF13499.6 KFM64386.1 - 2.2e-08 34.4 0.0 5.7e-07 29.9 0.0 3.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFM64386.1 - 9.8e-07 28.5 0.2 0.0041 16.9 0.0 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM64386.1 - 2.7e-06 26.8 0.1 0.0097 15.8 0.1 3.7 3 0 0 3 3 2 2 EF-hand domain SH3_2 PF07653.17 KFM64386.1 - 6.5e-06 25.7 0.0 1.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFM64386.1 - 0.039 14.2 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 Bacterial SH3 domain EF-hand_5 PF13202.6 KFM64386.1 - 0.05 13.1 0.0 0.35 10.5 0.0 2.6 2 0 0 2 2 2 0 EF hand GvpG PF05120.12 KFM64386.1 - 0.053 13.5 15.5 1 9.4 0.2 5.9 5 0 0 5 5 3 0 Gas vesicle protein G DUF2808 PF10989.8 KFM64386.1 - 0.61 10.1 3.6 2.1 8.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) DASH_Dam1 PF08653.10 KFM64386.1 - 0.88 9.4 11.9 23 4.9 0.2 7.5 6 0 0 6 6 6 0 DASH complex subunit Dam1 zf-MIZ PF02891.20 KFM64386.1 - 2.2 8.1 4.7 17 5.3 0.3 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger CnrY PF17524.2 KFM64386.1 - 6 7.2 7.8 23 5.3 0.1 4.8 5 0 0 5 5 4 0 Anti-sigma factor CnrY HTH_Tnp_Tc3_2 PF01498.18 KFM64387.1 - 2.3e-19 69.4 3.4 6e-19 68.1 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64387.1 - 5.2e-16 58.7 0.0 2.5e-15 56.5 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64387.1 - 3.8e-07 30.6 2.0 3.8e-07 30.6 2.0 2.3 3 0 0 3 3 3 1 Homeodomain-like domain MarR_2 PF12802.7 KFM64387.1 - 0.00037 20.3 0.5 0.0059 16.5 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_29 PF13551.6 KFM64387.1 - 0.0014 18.6 0.3 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 KFM64387.1 - 0.0016 18.4 0.3 0.021 14.8 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM64387.1 - 0.0016 18.5 0.8 0.33 11.1 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM64387.1 - 0.027 14.5 0.2 9.6 6.4 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM64387.1 - 0.03 14.1 1.6 1.3 8.9 0.0 2.9 2 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64388.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64388.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64389.1 - 2.3e-16 59.8 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64389.1 - 1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64391.1 - 1e-15 57.7 6.5 1.8e-15 56.9 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64391.1 - 1.8e-15 57.0 0.0 4.2e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Exo_endo_phos_2 PF14529.6 KFM64391.1 - 6.3e-12 45.4 0.1 1.6e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase HTH_32 PF13565.6 KFM64391.1 - 0.00091 19.8 1.5 0.00091 19.8 1.5 2.8 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM64391.1 - 0.0071 16.1 0.4 0.14 12.0 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64391.1 - 0.025 14.7 0.1 0.079 13.1 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM64391.1 - 0.043 13.8 0.4 0.043 13.8 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DNA_pol_B_2 PF03175.13 KFM64392.1 - 0.013 14.4 0.0 0.013 14.4 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Mito_carr PF00153.27 KFM64393.1 - 6.3e-64 211.9 4.1 1.7e-21 76.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Smg8_Smg9 PF10220.9 KFM64394.1 - 1.6e-58 198.9 0.1 1.7e-58 198.8 0.1 1.0 1 0 0 1 1 1 1 Smg8_Smg9 HLH PF00010.26 KFM64395.1 - 1.1e-16 60.5 0.1 1.8e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM64396.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64396.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SOBP PF15279.6 KFM64397.1 - 2e-24 87.8 41.6 2e-24 87.8 41.6 2.8 2 1 0 2 2 2 1 Sine oculis-binding protein SAP18 PF06487.12 KFM64398.1 - 1.5e-41 141.8 0.0 1.9e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) FMN_dh PF01070.18 KFM64401.1 - 3.8e-127 424.1 0.0 4.2e-127 423.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFM64401.1 - 3.2e-07 29.7 0.2 9.6e-07 28.1 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFM64401.1 - 9.4e-05 21.7 0.1 0.00016 20.9 0.1 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KFM64401.1 - 0.048 13.0 0.2 6 6.1 0.0 2.5 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KFM64401.1 - 0.052 13.0 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 KFM64401.1 - 0.12 11.8 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Astacin PF01400.24 KFM64402.1 - 7.6e-12 45.2 0.0 8.9e-12 45.0 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 KFM64402.1 - 0.011 16.1 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 0 CUB domain zinc_ribbon_2 PF13240.6 KFM64402.1 - 0.023 14.4 0.6 0.037 13.7 0.6 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.26 KFM64402.1 - 0.14 12.6 0.4 0.38 11.3 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1188 PF06690.11 KFM64403.1 - 0.092 12.3 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) ATP-synt_ab PF00006.25 KFM64404.1 - 4.8e-109 363.0 0.0 6.5e-109 362.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KFM64404.1 - 3e-44 149.7 0.0 6.8e-44 148.6 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KFM64404.1 - 1.5e-15 57.5 2.5 3.2e-15 56.4 2.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HTH_Tnp_Tc3_2 PF01498.18 KFM64405.1 - 2.1e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64405.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 KFM64407.1 - 3.2e-77 260.2 0.0 4.4e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM64407.1 - 1.3e-07 31.5 0.0 4e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Transposase DDE domain Peptidase_C71 PF12386.8 KFM64407.1 - 0.048 13.3 0.2 0.19 11.4 0.2 1.9 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei C1_2 PF03107.16 KFM64407.1 - 0.077 13.3 2.1 0.31 11.4 2.1 2.1 1 0 0 1 1 1 0 C1 domain Tnp_zf-ribbon_2 PF13842.6 KFM64407.1 - 1.6 9.6 12.2 5.7 7.8 12.2 2.0 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-B_box PF00643.24 KFM64407.1 - 8.4 6.6 9.7 20 5.5 9.7 1.7 1 0 0 1 1 1 0 B-box zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM64408.1 - 2.2e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64408.1 - 9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64410.1 - 5.2e-16 58.6 3.5 6.1e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64410.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64410.1 - 3.1e-07 30.1 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64410.1 - 0.0026 17.5 0.6 0.008 15.9 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64410.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Acetyltransf_1 PF00583.25 KFM64411.1 - 6.8e-07 29.5 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM64411.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM64411.1 - 0.027 14.9 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MULE PF10551.9 KFM64412.1 - 7.5e-20 71.2 1.3 7.5e-20 71.2 1.3 1.5 2 0 0 2 2 2 1 MULE transposase domain DUF4899 PF16240.5 KFM64412.1 - 0.011 14.9 5.4 0.016 14.5 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) EGF PF00008.27 KFM64413.1 - 6.9e-15 55.0 34.3 6.1e-08 32.8 8.0 3.4 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 KFM64413.1 - 1.7e-06 28.4 6.6 1.7e-06 28.4 6.6 4.6 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.13 KFM64413.1 - 0.0005 20.4 39.8 0.0017 18.7 10.7 3.4 3 1 0 3 3 3 2 EGF-like domain cEGF PF12662.7 KFM64413.1 - 0.0074 16.2 4.2 0.0074 16.2 4.2 3.1 2 1 0 2 2 2 1 Complement Clr-like EGF-like EGF_CA PF07645.15 KFM64413.1 - 0.31 11.3 34.2 0.46 10.7 8.8 3.3 2 1 1 3 3 3 0 Calcium-binding EGF domain Laminin_G_2 PF02210.24 KFM64415.1 - 0.00025 21.6 0.1 0.00035 21.2 0.1 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM64415.1 - 0.011 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain Laminin_G_2 PF02210.24 KFM64416.1 - 6.7e-14 52.6 0.0 7.5e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM64416.1 - 8.4e-13 48.7 0.0 9.4e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFM64417.1 - 2.7e-22 79.7 0.0 3.2e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM64417.1 - 2.8e-21 76.1 0.0 3.2e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFM64418.1 - 8.7e-07 29.6 0.1 9.9e-07 29.4 0.1 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM64418.1 - 0.0012 19.0 0.0 0.0013 19.0 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain HTH_Tnp_Tc3_2 PF01498.18 KFM64420.1 - 1.7e-19 69.8 3.8 3.9e-19 68.7 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64420.1 - 2.4e-16 59.8 0.0 1.3e-15 57.4 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64420.1 - 2.2e-07 31.4 4.3 2.4e-07 31.2 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM64420.1 - 0.00025 20.9 0.7 0.0041 17.0 0.0 2.5 1 1 1 2 2 2 1 MarR family HTH_29 PF13551.6 KFM64420.1 - 0.00074 19.5 0.3 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 KFM64420.1 - 0.00092 19.1 0.3 0.015 15.3 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM64420.1 - 0.0011 19.1 1.3 0.23 11.6 0.0 2.7 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 KFM64420.1 - 0.017 14.9 2.0 0.96 9.3 0.0 3.0 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 KFM64420.1 - 0.02 15.0 0.6 7.1 6.8 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 KFM64420.1 - 0.083 13.1 0.1 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain zf-C2H2 PF00096.26 KFM64422.1 - 4.5e-73 237.8 165.8 0.00041 20.6 1.6 23.2 23 0 0 23 23 23 22 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64422.1 - 7e-64 206.9 158.6 0.0017 19.0 0.8 23.2 23 0 0 23 23 23 21 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM64422.1 - 4.4e-32 109.1 152.2 0.0015 18.9 0.1 23.6 24 0 0 24 24 24 14 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFM64422.1 - 2.2e-23 81.7 149.1 0.006 16.6 0.1 21.9 22 0 0 22 22 22 17 C2H2-type zinc finger zf-met PF12874.7 KFM64422.1 - 1.3e-20 73.0 148.2 0.00098 19.4 0.3 23.0 23 0 0 23 23 23 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64422.1 - 9.9e-12 44.8 151.6 0.13 12.6 0.6 21.4 20 2 2 22 22 22 13 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM64422.1 - 1.9e-07 31.3 32.8 0.68 10.3 0.0 11.3 6 4 5 11 11 11 5 BolA-like protein zf-C2H2_11 PF16622.5 KFM64422.1 - 9.2e-05 22.1 0.7 9.2e-05 22.1 0.7 10.5 13 0 0 13 13 13 2 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFM64422.1 - 0.00081 20.1 102.0 0.16 12.7 7.5 11.5 3 1 11 14 14 14 6 zinc-ribbon family zf_UBZ PF18439.1 KFM64422.1 - 0.01 15.4 0.8 0.01 15.4 0.8 20.1 22 0 0 22 22 22 5 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KFM64422.1 - 0.021 15.1 90.8 0.036 14.4 7.5 10.5 2 1 8 11 11 11 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KFM64422.1 - 5.2 7.1 88.6 1.9 8.5 0.2 18.0 20 0 0 20 20 20 0 zinc-finger of a C2HC-type FYVE PF01363.21 KFM64422.1 - 9.3 6.5 115.1 2.3 8.4 5.3 12.4 4 3 10 14 14 14 0 FYVE zinc finger DDE_Tnp_1_7 PF13843.6 KFM64423.1 - 1.2e-45 156.3 3.1 1.7e-45 155.9 3.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Pex14_N PF04695.13 KFM64423.1 - 0.061 14.0 0.4 0.061 14.0 0.4 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Stork_head PF10264.9 KFM64423.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Chitin_bind_4 PF00379.23 KFM64425.1 - 3.2e-12 46.8 2.8 5.4e-12 46.0 2.8 1.4 1 0 0 1 1 1 1 Insect cuticle protein CBM_14 PF01607.24 KFM64426.1 - 8.2e-17 61.1 19.7 3.5e-10 39.9 6.9 2.6 2 1 0 2 2 2 2 Chitin binding Peritrophin-A domain V_ATPase_I PF01496.19 KFM64427.1 - 0 1113.7 0.0 0 1113.4 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6_N PF17675.1 KFM64427.1 - 0.17 12.4 3.4 0.27 11.8 3.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region TPK_B1_binding PF04265.14 KFM64428.1 - 9.9e-21 73.2 0.2 1.5e-20 72.6 0.2 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain HTH_48 PF17906.1 KFM64428.1 - 7.4e-05 22.8 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Ribosomal_L13 PF00572.18 KFM64428.1 - 0.034 14.4 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L13 Collagen_bind PF05737.12 KFM64428.1 - 0.056 13.6 0.3 0.087 13.0 0.2 1.6 1 1 0 1 1 1 0 Collagen binding domain RT_RNaseH_2 PF17919.1 KFM64429.1 - 5.7e-31 106.5 0.0 1.5e-30 105.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM64429.1 - 3.4e-28 98.7 1.3 6.8e-28 97.7 0.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM64429.1 - 4.6e-28 97.6 0.0 1.4e-27 96.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM64429.1 - 6.7e-20 71.0 0.2 2.7e-19 69.0 0.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM64429.1 - 5.7e-18 65.2 0.0 1.6e-15 57.4 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KFM64429.1 - 2.5e-09 37.6 0.0 8.4e-09 35.9 0.0 2.0 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM64429.1 - 1.3e-05 25.7 0.0 3.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM64429.1 - 1.5e-05 25.2 0.0 4.5e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KFM64429.1 - 4.5e-05 23.6 1.0 0.00012 22.3 1.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KFM64429.1 - 7.4e-05 22.5 0.0 0.0002 21.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_3 PF13456.6 KFM64429.1 - 0.0023 17.7 0.1 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Asp_protease PF09668.10 KFM64429.1 - 0.003 17.4 0.1 0.0067 16.2 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease BH4 PF02180.17 KFM64429.1 - 0.052 13.4 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Bcl-2 homology region 4 BEN PF10523.9 KFM64429.1 - 0.15 12.3 0.5 3.4 8.0 0.0 3.2 2 0 0 2 2 2 0 BEN domain TPK_catalytic PF04263.16 KFM64430.1 - 4.9e-33 113.7 0.1 7.2e-33 113.2 0.1 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain DUF3155 PF11352.8 KFM64430.1 - 0.044 14.2 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) Transposase_1 PF01359.18 KFM64430.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Transposase (partial DDE domain) Laminin_G_2 PF02210.24 KFM64431.1 - 2.4e-45 154.2 1.5 1.8e-25 90.0 0.2 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFM64431.1 - 2.9e-33 114.9 0.8 1.2e-19 70.8 0.0 2.9 2 1 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFM64431.1 - 5e-08 33.1 7.6 1.3e-07 31.8 7.6 1.8 1 0 0 1 1 1 1 EGF-like domain Laminin_G_3 PF13385.6 KFM64431.1 - 0.00015 22.0 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Cys_box PF17869.1 KFM64431.1 - 0.12 12.6 1.6 0.27 11.4 1.6 1.5 1 0 0 1 1 1 0 Anosmin cysteine rich domain hEGF PF12661.7 KFM64431.1 - 0.73 10.6 5.0 0.41 11.4 1.9 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF Laminin_G_2 PF02210.24 KFM64432.1 - 8.7e-31 107.1 0.3 2e-21 76.9 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFM64432.1 - 2.4e-16 60.1 0.5 4.3e-13 49.6 0.1 2.5 2 1 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 KFM64432.1 - 2.8e-10 40.5 0.1 1.5e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFM64432.1 - 4.1e-07 30.2 8.2 4.1e-07 30.2 8.2 2.8 2 1 0 2 2 2 1 EGF-like domain hEGF PF12661.7 KFM64432.1 - 0.0016 19.0 6.1 0.0016 19.0 6.1 3.7 3 1 1 4 4 4 1 Human growth factor-like EGF EGF_2 PF07974.13 KFM64432.1 - 5.2 7.5 29.5 1.1 9.7 13.5 2.5 2 0 0 2 2 2 0 EGF-like domain BTB PF00651.31 KFM64434.1 - 1.4e-20 73.6 0.3 4.6e-19 68.7 0.2 2.5 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM64434.1 - 4e-06 26.9 3.6 7.9e-06 25.9 0.4 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 KFM64435.1 - 1e-17 64.4 0.3 1.2e-15 57.7 0.2 2.4 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM64435.1 - 1.1e-07 31.9 4.2 2e-05 24.6 0.3 3.0 3 0 0 3 3 3 2 BTB And C-terminal Kelch ABC_membrane PF00664.23 KFM64436.1 - 0.032 13.9 0.1 0.034 13.8 0.1 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region DDE_3 PF13358.6 KFM64437.1 - 3.2e-11 43.2 0.0 4.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64438.1 - 4.3e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64438.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64438.1 - 1.6e-07 30.9 1.2 6.7e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64438.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64438.1 - 2 9.1 15.6 0.12 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64439.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64439.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64440.1 - 4.5e-16 58.9 3.5 5.6e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64440.1 - 8.3e-13 48.3 0.0 1.5e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64440.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64440.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64440.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Actin PF00022.19 KFM64441.1 - 3.2e-33 115.0 0.0 8.8e-31 106.9 0.0 3.5 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 KFM64441.1 - 1.3e-11 44.3 1.2 8.7e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 KFM64441.1 - 0.0055 15.6 0.0 0.061 12.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein ISN1 PF06437.11 KFM64441.1 - 0.022 13.7 0.4 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 IMP-specific 5'-nucleotidase IBN_N PF03810.19 KFM64442.1 - 1.4e-08 34.5 2.2 6e-06 26.1 0.3 4.0 4 0 0 4 4 4 2 Importin-beta N-terminal domain Xpo1 PF08389.12 KFM64442.1 - 0.0011 19.0 4.6 0.015 15.4 0.4 3.7 3 0 0 3 3 3 1 Exportin 1-like protein DUF5601 PF18151.1 KFM64442.1 - 0.13 12.6 0.1 0.44 10.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) HTH_53 PF18606.1 KFM64444.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain Galactosyl_T PF01762.21 KFM64448.1 - 5.6e-42 143.8 0.2 7.3e-42 143.4 0.2 1.1 1 0 0 1 1 1 1 Galactosyltransferase MACPF PF01823.19 KFM64452.1 - 1.1e-07 32.2 0.1 3.7e-06 27.2 0.0 2.3 2 1 0 2 2 2 1 MAC/Perforin domain Mt_ATP-synt_D PF05873.12 KFM64452.1 - 0.027 14.3 1.4 0.058 13.2 0.9 1.8 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Dynamin_M PF01031.20 KFM64452.1 - 0.051 12.8 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Dynamin central region EzrA PF06160.12 KFM64452.1 - 0.066 11.4 3.2 0.17 10.0 2.6 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF148 PF02520.17 KFM64452.1 - 0.36 10.9 2.0 16 5.6 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF148 MACPF PF01823.19 KFM64453.1 - 4.5e-07 30.2 0.2 6.8e-06 26.3 0.0 2.4 3 0 0 3 3 3 1 MAC/Perforin domain Dynamin_M PF01031.20 KFM64453.1 - 0.03 13.5 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 Dynamin central region Mt_ATP-synt_D PF05873.12 KFM64453.1 - 0.078 12.8 1.0 0.45 10.4 1.0 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) UPF0184 PF03670.13 KFM64453.1 - 0.11 12.9 1.0 0.2 12.0 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Stc1 PF12898.7 KFM64454.1 - 0.084 13.4 0.8 0.084 13.4 0.8 2.2 1 1 1 2 2 2 0 Stc1 domain zf-H2C2_2 PF13465.6 KFM64455.1 - 4.9e-65 213.3 80.9 1.2e-07 31.8 2.7 11.1 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64455.1 - 1.6e-49 163.7 89.9 3.1e-06 27.3 1.6 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64455.1 - 7.9e-33 110.3 85.0 0.00046 20.8 1.5 10.3 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM64455.1 - 1.8e-20 72.6 72.1 7.2e-05 23.0 1.7 10.6 10 1 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64455.1 - 7.8e-19 67.5 54.1 0.019 15.3 0.7 10.7 10 1 0 10 10 10 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM64455.1 - 1.8e-09 37.4 68.7 0.12 12.4 0.7 10.6 10 0 0 10 10 10 6 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM64455.1 - 1.3e-07 31.5 30.9 0.62 10.2 0.1 9.5 5 4 5 10 10 10 2 Sec23/Sec24 zinc finger zf-CHCC PF10276.9 KFM64455.1 - 0.00015 21.7 8.6 48 4.1 0.0 8.2 9 0 0 9 9 9 0 Zinc-finger domain DUF2256 PF10013.9 KFM64455.1 - 0.00018 21.6 34.4 6 7.1 0.1 9.8 10 0 0 10 10 10 1 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM64455.1 - 0.0011 18.9 33.8 0.54 10.3 1.4 6.2 4 2 1 5 5 5 3 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM64455.1 - 0.003 17.1 46.8 0.045 13.4 0.6 9.5 3 2 7 10 10 10 3 MYST family zinc finger domain GAGA PF09237.11 KFM64455.1 - 0.0047 16.7 17.0 2.8 7.8 0.0 6.4 2 2 4 7 7 7 1 GAGA factor DUF2039 PF10217.9 KFM64455.1 - 0.014 15.7 35.2 1.8 8.9 4.7 5.0 1 1 5 6 6 6 0 Uncharacterized conserved protein (DUF2039) zf-C2H2_9 PF16293.5 KFM64455.1 - 0.038 13.8 39.7 2 8.3 0.4 8.9 3 3 7 10 10 10 0 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 KFM64455.1 - 0.056 13.2 0.5 0.056 13.2 0.5 10.4 11 0 0 11 11 10 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM64455.1 - 0.057 13.7 63.0 1.8 9.0 1.8 9.5 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM64455.1 - 0.067 13.3 35.2 3.3 7.8 8.4 4.4 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type XPA_N PF01286.18 KFM64455.1 - 0.079 13.0 31.8 5.5 7.1 0.1 9.6 10 0 0 10 10 10 0 XPA protein N-terminal BolA PF01722.18 KFM64455.1 - 0.22 11.8 19.0 0.51 10.7 0.5 5.5 1 1 3 4 4 4 0 BolA-like protein Zn-ribbon_8 PF09723.10 KFM64455.1 - 0.22 11.6 35.0 0.2 11.8 0.9 6.6 3 2 4 7 7 7 0 Zinc ribbon domain DUF3338 PF11819.8 KFM64455.1 - 0.22 11.5 0.9 77 3.3 0.0 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF3338) Complex1_49kDa PF00346.19 KFM64455.1 - 0.23 10.5 0.3 4 6.4 0.0 2.1 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zinc_ribbon_15 PF17032.5 KFM64455.1 - 0.45 11.3 34.3 6.5 7.6 0.9 5.6 1 1 4 5 5 5 0 zinc-ribbon family zf_UBZ PF18439.1 KFM64455.1 - 1 9.0 38.8 0.78 9.4 0.2 9.3 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger BHD_1 PF10403.9 KFM64455.1 - 1.3 8.9 11.2 43 4.0 0.1 5.3 4 2 2 6 6 6 0 Rad4 beta-hairpin domain 1 zf-DBF PF07535.12 KFM64455.1 - 3.2 7.9 37.0 12 6.2 0.1 8.4 9 0 0 9 9 8 0 DBF zinc finger DUF3268 PF11672.8 KFM64455.1 - 7.9 6.8 21.6 11 6.4 0.4 5.0 3 1 0 5 5 5 0 zinc-finger-containing domain NDUF_B8 PF05821.11 KFM64456.1 - 2.1e-33 115.7 3.5 2.5e-33 115.4 3.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Pex2_Pex12 PF04757.14 KFM64457.1 - 3.4e-11 43.2 9.6 6.1e-11 42.4 9.6 1.3 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region WD40 PF00400.32 KFM64458.1 - 6e-34 115.5 6.1 1.2e-09 38.7 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM64458.1 - 1.3e-09 38.2 0.0 0.3 11.4 0.0 5.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM64458.1 - 1.1e-05 24.6 0.1 0.11 11.5 0.0 3.5 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PTPA PF03095.15 KFM64459.1 - 1.1e-122 409.2 0.0 1.2e-122 409.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein HTH_23 PF13384.6 KFM64460.1 - 0.032 14.0 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain LRR_8 PF13855.6 KFM64461.1 - 3.5e-11 42.7 5.0 7.4e-08 32.0 1.0 3.0 2 1 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 KFM64461.1 - 0.031 13.8 2.4 4.4 6.8 0.1 2.8 1 1 2 3 3 3 0 Leucine-rich repeat TPKR_C2 PF16920.5 KFM64461.1 - 0.059 13.5 0.3 0.15 12.2 0.3 1.7 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_4 PF12799.7 KFM64461.1 - 0.11 12.9 0.1 0.11 12.9 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM64462.1 - 1.2e-17 63.4 9.1 1.1e-11 44.3 0.5 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_5 PF13306.6 KFM64462.1 - 3.5e-08 33.5 0.1 1.9e-05 24.6 0.0 2.5 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM64462.1 - 5.5e-06 26.6 9.2 0.00026 21.3 0.1 4.2 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM64462.1 - 3.4e-05 23.4 0.5 0.24 10.9 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFM64462.1 - 2.2 9.1 0.0 2.2 9.1 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 KFM64463.1 - 1e-21 76.4 8.3 6.3e-14 51.5 0.5 4.3 2 2 2 4 4 4 2 Leucine rich repeat LRR_5 PF13306.6 KFM64463.1 - 2.6e-11 43.6 0.3 7e-09 35.7 0.0 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM64463.1 - 1.5e-09 37.6 1.8 9.1e-06 25.3 1.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFM64463.1 - 1.7e-08 34.6 7.7 0.012 16.0 0.8 4.8 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM64463.1 - 0.027 14.5 0.1 37 4.7 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KFM64463.1 - 0.033 14.7 6.9 28 5.8 0.0 5.9 6 1 0 6 6 6 0 Leucine Rich Repeat RE_MamI PF09567.10 KFM64463.1 - 0.072 12.7 0.2 10 5.7 0.0 2.3 2 0 0 2 2 2 0 MamI restriction endonuclease Omega-toxin PF06357.11 KFM64464.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Omega-atracotoxin LRR_8 PF13855.6 KFM64466.1 - 1e-17 63.6 4.2 1.3e-10 40.8 0.1 4.1 1 1 2 4 4 4 2 Leucine rich repeat LRR_5 PF13306.6 KFM64466.1 - 9.8e-07 28.8 0.3 0.00065 19.7 0.0 2.3 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM64466.1 - 3.3e-06 26.7 0.7 0.013 15.1 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFM64466.1 - 4.1e-06 27.0 10.0 5.6e-06 26.6 0.3 4.4 3 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM64466.1 - 0.0032 17.4 0.6 0.23 11.6 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeat Galactosyl_T PF01762.21 KFM64468.1 - 5.9e-49 166.5 0.1 7.8e-49 166.2 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase EF-hand_6 PF13405.6 KFM64469.1 - 0.00011 21.8 0.1 0.001 18.8 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KFM64469.1 - 0.00099 19.5 0.8 0.003 18.0 0.2 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM64469.1 - 0.0015 18.0 0.3 0.0071 15.8 0.0 2.3 3 0 0 3 3 3 1 EF hand EF-hand_11 PF08976.11 KFM64469.1 - 0.0058 17.5 0.0 0.0072 17.2 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KFM64469.1 - 0.12 12.2 0.2 0.88 9.5 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KFM64471.1 - 0.00041 19.7 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFM64471.1 - 0.00045 19.9 0.7 0.00064 19.4 0.1 1.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KFM64471.1 - 0.0025 17.2 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFM64471.1 - 0.0095 16.4 0.1 0.01 16.2 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KFM64471.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain pair Endosulfine PF04667.17 KFM64472.1 - 2.2e-10 40.5 0.3 3.1e-10 40.0 0.3 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ThiF PF00899.21 KFM64473.1 - 4.9e-72 242.2 0.2 9.4e-72 241.3 0.1 1.4 2 0 0 2 2 2 1 ThiF family UAE_UbL PF14732.6 KFM64473.1 - 2.5e-16 60.1 2.2 4e-16 59.4 0.6 2.3 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KFM64473.1 - 5.5e-11 42.9 0.1 3.3e-07 30.5 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KFM64473.1 - 0.0034 17.8 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KFM64473.1 - 0.025 14.6 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RcsC PF09456.10 KFM64473.1 - 0.079 13.0 0.0 27 4.9 0.0 2.8 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) NDUF_B6 PF09782.9 KFM64474.1 - 1.5e-37 129.1 0.3 1.8e-37 128.9 0.3 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DDE_Tnp_IS1595 PF12762.7 KFM64475.1 - 4.6e-07 30.0 0.0 5.1e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain ATP-synt_S1 PF05827.12 KFM64476.1 - 4e-26 91.6 0.3 8.2e-26 90.6 0.3 1.5 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.17 KFM64476.1 - 0.024 14.5 0.6 0.098 12.5 0.0 2.3 3 0 0 3 3 3 0 Lysosome-associated membrane glycoprotein (Lamp) MH2 PF03166.14 KFM64479.1 - 1.3e-75 253.8 0.9 1.8e-75 253.2 0.9 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFM64479.1 - 1.9e-42 143.7 1.2 3.8e-42 142.7 1.2 1.5 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFM64479.1 - 0.0026 17.6 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 RrnaAD PF00398.20 KFM64480.1 - 7.8e-63 212.0 0.3 9.5e-63 211.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KFM64480.1 - 5e-07 30.3 0.0 9.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFM64480.1 - 1.9e-05 24.6 0.0 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KFM64480.1 - 0.00019 22.0 0.0 0.00038 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KFM64480.1 - 0.00085 18.9 0.0 0.0031 17.1 0.0 1.9 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 KFM64480.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KFM64480.1 - 0.0022 17.9 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM64480.1 - 0.0033 17.0 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KFM64480.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_31 PF13847.6 KFM64480.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KFM64480.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KFM64480.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KFM64480.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KFM64480.1 - 0.026 14.3 0.0 6.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF938) tRNA_U5-meth_tr PF05958.11 KFM64480.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase HCNGP PF07818.13 KFM64480.1 - 0.056 14.1 0.1 0.14 12.8 0.1 1.6 1 0 0 1 1 1 0 HCNGP-like protein Ubie_methyltran PF01209.18 KFM64480.1 - 0.057 12.7 0.1 0.094 12.0 0.1 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFM64480.1 - 0.089 13.5 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KFM64480.1 - 0.11 12.3 0.7 0.31 10.9 0.1 1.9 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Ribosomal_L23 PF00276.20 KFM64481.1 - 1.9e-16 60.2 1.6 3.4e-16 59.4 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 DUF1221 PF06760.11 KFM64481.1 - 0.077 12.5 0.3 0.096 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) POPLD PF08170.12 KFM64481.1 - 0.085 13.2 0.8 0.14 12.6 0.8 1.4 1 0 0 1 1 1 0 POPLD (NUC188) domain zf-H2C2_2 PF13465.6 KFM64482.1 - 1.7e-73 240.0 97.5 3.2e-09 36.8 2.4 15.2 15 0 0 15 15 15 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64482.1 - 5e-64 209.4 133.6 4.4e-06 26.8 1.4 14.2 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64482.1 - 4.2e-47 154.7 122.1 0.0011 19.6 3.3 14.2 14 0 0 14 14 14 13 C2H2-type zinc finger zf-met PF12874.7 KFM64482.1 - 3.7e-28 97.0 97.9 0.00082 19.7 0.8 13.5 13 0 0 13 13 13 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM64482.1 - 1.1e-26 92.2 93.4 0.0028 17.6 0.2 14.7 14 0 0 14 14 14 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM64482.1 - 6.4e-18 64.6 82.8 0.06 13.6 0.1 13.8 12 1 2 14 14 14 11 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM64482.1 - 2.6e-06 27.3 36.7 0.065 13.2 1.0 8.5 7 3 1 8 8 8 3 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KFM64482.1 - 6e-05 22.7 79.1 0.0017 18.0 0.3 12.5 13 0 0 13 13 12 5 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 KFM64482.1 - 9.8e-05 23.0 50.8 0.62 10.8 5.5 7.9 4 2 4 8 8 8 5 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM64482.1 - 0.00021 21.6 92.2 5 7.5 1.1 12.6 1 1 9 11 11 11 2 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM64482.1 - 0.022 14.9 48.4 5.1 7.3 2.7 5.8 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type GAGA PF09237.11 KFM64482.1 - 0.051 13.4 45.8 0.073 12.9 0.0 9.9 2 2 10 12 12 12 0 GAGA factor zf-C2HC_2 PF13913.6 KFM64482.1 - 0.088 12.7 55.5 0.76 9.8 0.3 12.4 14 0 0 14 14 14 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM64482.1 - 0.1 12.2 49.3 0.13 11.9 0.3 10.9 6 3 6 12 12 12 0 MYST family zinc finger domain GATA PF00320.27 KFM64482.1 - 0.47 10.1 0.0 0.47 10.1 0.0 8.2 9 2 1 10 10 10 0 GATA zinc finger RVT_1 PF00078.27 KFM64483.1 - 0.023 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_4 PF14392.6 KFM64484.1 - 0.039 13.7 1.9 0.054 13.2 0.6 1.9 2 0 0 2 2 2 0 Zinc knuckle fn3 PF00041.21 KFM64485.1 - 5.1e-58 193.4 10.3 7.2e-19 67.9 0.3 5.1 5 0 0 5 5 5 4 Fibronectin type III domain I-set PF07679.16 KFM64485.1 - 2e-19 69.4 0.0 1.1e-12 47.8 0.0 3.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM64485.1 - 6.4e-18 65.1 0.1 1.8e-11 44.5 0.0 3.2 2 0 0 2 2 2 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM64485.1 - 4.4e-16 59.2 8.1 3.5e-08 33.9 0.1 4.7 3 1 1 4 4 4 2 Purple acid Phosphatase, N-terminal domain ig PF00047.25 KFM64485.1 - 1e-11 44.9 0.0 3.7e-06 27.0 0.0 3.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM64485.1 - 2.4e-09 37.4 0.0 9.1e-06 25.9 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM64485.1 - 2.7e-09 37.2 0.3 0.0039 17.3 0.1 3.6 3 1 0 3 3 2 2 Immunoglobulin V-set domain DUF2369 PF10179.9 KFM64485.1 - 3.2e-07 30.6 0.0 0.96 9.9 0.0 4.3 4 0 0 4 4 4 3 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFM64485.1 - 4.5e-07 30.1 0.2 0.94 9.8 0.0 4.4 4 1 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 KFM64485.1 - 1.4e-06 28.4 0.3 0.001 19.2 0.0 3.1 3 0 0 3 3 3 1 Fibronectin type III domain fn3_4 PF16794.5 KFM64485.1 - 0.00051 19.9 0.0 3.2 7.7 0.1 3.7 2 1 0 2 2 2 2 Fibronectin-III type domain Ig_6 PF18452.1 KFM64485.1 - 0.0013 18.2 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain TMEM154 PF15102.6 KFM64485.1 - 0.0035 17.2 1.5 0.014 15.3 0.4 2.4 2 1 0 2 2 2 1 TMEM154 protein family Baculo_11_kDa PF06143.11 KFM64485.1 - 0.0048 16.4 1.0 0.011 15.3 1.0 1.5 1 0 0 1 1 1 1 Baculovirus 11 kDa family PhoD_N PF16655.5 KFM64485.1 - 0.0054 17.2 0.1 0.48 11.0 0.0 3.4 3 0 0 3 3 3 1 PhoD-like phosphatase, N-terminal domain DUF4998 PF16389.5 KFM64485.1 - 0.0096 15.5 0.5 0.31 10.6 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function EphA2_TM PF14575.6 KFM64485.1 - 0.012 16.5 0.0 0.027 15.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Receptor_2B4 PF11465.8 KFM64485.1 - 0.036 14.3 0.0 2.2 8.5 0.0 2.8 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 C2-set PF05790.15 KFM64485.1 - 0.037 14.2 0.1 2 8.7 0.0 2.9 3 0 0 3 3 2 0 Immunoglobulin C2-set domain Reeler PF02014.16 KFM64485.1 - 0.093 13.5 0.1 49 4.7 0.0 4.1 4 0 0 4 4 4 0 Reeler domain Izumo-Ig PF16706.5 KFM64485.1 - 0.12 12.4 0.0 9 6.4 0.0 2.7 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Shisa PF13908.6 KFM64485.1 - 0.13 12.5 0.2 0.32 11.2 0.2 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator AMP-binding PF00501.28 KFM64488.1 - 1.2e-15 57.0 0.0 1.7e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TBPIP_N PF15517.6 KFM64488.1 - 0.05 13.6 0.2 0.098 12.7 0.2 1.4 1 0 0 1 1 1 0 TBP-interacting protein N-terminus AMP-binding PF00501.28 KFM64489.1 - 4.2e-13 48.7 0.0 4.8e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF485 PF04341.12 KFM64491.1 - 2.4 8.2 0.0 2.4 8.2 0.0 5.2 6 0 0 6 6 6 0 Protein of unknown function, DUF485 DDE_3 PF13358.6 KFM64493.1 - 4.3e-11 42.8 0.0 5e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM64494.1 - 1.2e-74 243.6 92.2 3.1e-10 40.0 0.3 13.4 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64494.1 - 2.1e-57 188.5 117.1 5.5e-06 26.5 3.0 13.2 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64494.1 - 6e-37 123.1 106.2 0.0015 19.2 1.9 13.1 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM64494.1 - 8.3e-25 86.3 84.9 4.1e-06 26.7 0.6 13.6 13 0 0 13 13 13 11 C2H2-type zinc finger zf-met PF12874.7 KFM64494.1 - 1.8e-23 82.2 96.8 0.0026 18.1 0.8 13.4 13 0 0 13 13 13 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64494.1 - 6.5e-17 61.3 81.5 0.00039 20.6 2.3 12.9 12 1 1 13 13 13 9 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM64494.1 - 7.7e-05 22.9 17.6 1.4 9.3 0.4 7.4 1 1 6 8 8 8 3 BolA-like protein Mga PF05043.13 KFM64494.1 - 0.28 11.8 7.7 18 6.0 0.0 4.1 4 0 0 4 4 4 0 Mga helix-turn-helix domain Ribosomal_L35p PF01632.19 KFM64494.1 - 2.7 8.6 0.0 2.7 8.6 0.0 4.4 6 1 0 6 6 6 0 Ribosomal protein L35 GAGA PF09237.11 KFM64494.1 - 4.9 7.0 32.3 7.4 6.5 0.3 7.2 1 1 8 9 9 9 0 GAGA factor ADK_lid PF05191.14 KFM64494.1 - 8 6.5 41.4 0.055 13.5 2.4 7.9 6 2 2 8 8 8 0 Adenylate kinase, active site lid DUF4516 PF14990.6 KFM64496.1 - 0.059 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) Maelstrom PF13017.6 KFM64496.1 - 0.064 12.9 0.1 0.076 12.7 0.1 1.1 1 0 0 1 1 1 0 piRNA pathway germ-plasm component HTH_Tnp_Tc3_2 PF01498.18 KFM64497.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64497.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64497.1 - 1.7e-07 30.9 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64497.1 - 0.0023 17.6 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64497.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain FoP_duplication PF13865.6 KFM64498.1 - 2.1e-12 47.4 14.4 2.1e-12 47.4 14.4 3.6 3 2 2 5 5 5 2 C-terminal duplication domain of Friend of PRMT1 Gp-FAR-1 PF05823.12 KFM64500.1 - 0.53 10.6 10.3 0.091 13.1 4.0 2.8 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) COX4 PF02936.14 KFM64500.1 - 1.7 8.6 8.2 11 6.0 2.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV TBCC PF07986.12 KFM64501.1 - 2.2e-42 143.6 10.8 3.3e-42 143.0 10.8 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 KFM64501.1 - 8.6e-08 32.0 4.4 1.4e-07 31.3 4.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DDE_3 PF13358.6 KFM64502.1 - 8.3e-17 61.3 0.1 7.9e-16 58.1 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64502.1 - 2.7e-10 40.3 1.0 2.7e-10 40.3 1.0 1.7 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM64503.1 - 2.4e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64503.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Sushi PF00084.20 KFM64504.1 - 5.5e-12 46.1 33.6 0.0001 22.8 5.8 4.9 4 1 0 4 4 4 4 Sushi repeat (SCR repeat) Lyase_8 PF02278.18 KFM64504.1 - 1.2e-05 24.9 0.5 0.14 11.6 0.3 3.2 2 1 0 3 3 3 3 Polysaccharide lyase family 8, super-sandwich domain TIL PF01826.17 KFM64507.1 - 1.5e-10 41.2 21.6 1.5e-10 41.2 21.6 4.3 4 1 1 5 5 5 1 Trypsin Inhibitor like cysteine rich domain VWD PF00094.25 KFM64507.1 - 1.1e-09 38.8 1.4 1.1e-09 38.8 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type D domain Pacifastin_I PF05375.13 KFM64507.1 - 7.8e-07 28.7 10.1 7.8e-07 28.7 10.1 4.3 3 2 0 3 3 3 1 Pacifastin inhibitor (LCMII) C8 PF08742.11 KFM64507.1 - 3e-06 27.6 5.2 3e-06 27.6 5.2 3.4 3 1 1 4 4 4 1 C8 domain VWC PF00093.18 KFM64507.1 - 2.5e-05 24.5 5.4 2.5e-05 24.5 5.4 3.6 2 1 0 2 2 2 1 von Willebrand factor type C domain F5_F8_type_C PF00754.25 KFM64508.1 - 2e-146 480.4 29.3 1.3e-26 93.2 0.5 6.3 6 0 0 6 6 6 6 F5/8 type C domain Mucin2_WxxW PF13330.6 KFM64508.1 - 4e-40 136.5 14.8 5.2e-17 62.5 2.8 6.2 7 0 0 7 7 7 3 Mucin-2 protein WxxW repeating region C8 PF08742.11 KFM64508.1 - 1.2e-28 99.3 27.2 6.1e-18 65.0 12.0 5.9 5 1 1 6 6 6 2 C8 domain VWD PF00094.25 KFM64508.1 - 1.8e-27 96.5 0.9 7.9e-27 94.5 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type D domain TIL PF01826.17 KFM64508.1 - 4.4e-18 65.3 95.1 1.9e-09 37.6 17.0 10.1 12 0 0 12 12 12 4 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFM64508.1 - 0.0018 18.5 6.7 0.0018 18.5 6.7 11.6 4 3 5 9 9 9 2 von Willebrand factor type C domain DUF736 PF05284.12 KFM64508.1 - 0.05 13.5 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF736) F5_F8_type_C PF00754.25 KFM64509.1 - 8.1e-26 90.6 0.2 1e-25 90.3 0.2 1.1 1 0 0 1 1 1 1 F5/8 type C domain Lactamase_B PF00753.27 KFM64511.1 - 1.1e-17 64.7 1.0 9.5e-16 58.4 1.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFM64511.1 - 0.0012 18.4 1.1 0.0025 17.4 1.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ACC_central PF08326.12 KFM64514.1 - 7.6e-273 907.2 5.8 9.5e-273 906.8 5.8 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 KFM64514.1 - 1.6e-50 171.5 0.0 3.4e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFM64514.1 - 2.1e-31 108.7 0.0 5.2e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFM64514.1 - 2.5e-22 79.0 0.0 1.8e-21 76.2 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Carboxyl_trans PF01039.22 KFM64514.1 - 1.7e-17 63.3 0.0 2.7e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain Biotin_lipoyl PF00364.22 KFM64514.1 - 7.2e-13 48.2 0.0 1.8e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFM64514.1 - 0.00087 18.9 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFM64514.1 - 0.0017 17.9 0.0 0.0048 16.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFM64514.1 - 0.004 17.2 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain MetallophosN PF16371.5 KFM64514.1 - 0.14 12.4 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 N terminal of Calcineurin-like phosphoesterase THF_DHG_CYH_C PF02882.19 KFM64514.1 - 0.15 11.4 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM64518.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64518.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Lig_chan PF00060.26 KFM64519.1 - 1.8e-21 76.5 0.3 2.2e-21 76.3 0.3 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel UCH PF00443.29 KFM64520.1 - 5.1e-32 111.4 0.7 5.1e-32 111.4 0.7 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KFM64520.1 - 6.5e-06 26.0 0.1 1.4e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 KFM64520.1 - 9.9e-06 25.4 0.1 0.00099 18.8 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-H2C2_5 PF13909.6 KFM64521.1 - 0.02 14.7 9.5 0.02 14.7 9.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFM64521.1 - 0.18 12.3 11.3 2 9.0 4.9 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64521.1 - 1.5 9.4 21.1 0.14 12.7 9.7 2.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type HTH_Tnp_Tc3_2 PF01498.18 KFM64522.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64522.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64522.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64522.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64522.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain BAR_3_WASP_bdg PF10456.9 KFM64523.1 - 4e-82 275.2 3.4 5.2e-82 274.8 3.4 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 KFM64523.1 - 3.1e-21 75.5 1.5 7.4e-21 74.2 0.1 2.2 2 1 0 2 2 2 1 PX domain SH3_9 PF14604.6 KFM64523.1 - 1e-11 44.5 0.3 2.4e-11 43.3 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM64523.1 - 4.1e-11 42.3 0.1 1.2e-10 40.8 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM64523.1 - 4.5e-10 39.0 0.1 1e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 KFM64523.1 - 4.5e-07 29.6 0.7 0.00014 21.5 0.7 2.4 1 1 0 1 1 1 1 Vps5 C terminal like GP57 PF17594.2 KFM64523.1 - 0.021 14.6 0.3 0.26 11.1 0.1 2.4 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 BAR PF03114.18 KFM64523.1 - 0.29 10.8 5.4 1.8 8.1 5.4 2.1 1 1 0 1 1 1 0 BAR domain EST1 PF10374.9 KFM64523.1 - 1 10.0 3.6 4.4 7.9 0.4 2.7 1 1 1 2 2 2 0 Telomerase activating protein Est1 DDE_3 PF13358.6 KFM64525.1 - 1.3e-05 25.0 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64526.1 - 2.5e-16 59.7 2.2 5e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64526.1 - 1.1e-13 51.2 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64527.1 - 6.9e-17 61.5 0.4 1.3e-16 60.6 0.4 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM64527.1 - 5.9e-05 23.6 5.1 0.00013 22.5 1.2 2.3 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM64527.1 - 0.00012 21.9 0.5 0.022 14.7 0.0 2.6 1 1 1 2 2 2 1 MarR family HTH_3 PF01381.22 KFM64527.1 - 0.00074 19.5 0.5 0.057 13.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 KFM64527.1 - 0.0013 18.9 1.3 0.056 13.6 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64527.1 - 0.0015 18.2 3.0 0.023 14.5 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM64527.1 - 0.0043 17.0 0.8 0.048 13.6 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM64527.1 - 0.01 15.4 1.4 0.41 10.2 0.0 2.9 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding PAX PF00292.18 KFM64527.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 1 0 1 1 1 0 'Paired box' domain HTH_26 PF13443.6 KFM64527.1 - 0.059 13.8 0.1 5.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Trp_repressor PF01371.19 KFM64527.1 - 0.13 12.4 0.1 0.31 11.2 0.0 1.6 2 0 0 2 2 2 0 Trp repressor protein TrmB PF01978.19 KFM64527.1 - 0.14 12.1 0.0 3 7.8 0.0 2.3 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Tnp_Tc3_2 PF01498.18 KFM64528.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64528.1 - 1.1e-11 44.7 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM64529.1 - 8.4e-10 38.7 0.0 2.6e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) DNA_pol_B_2 PF03175.13 KFM64530.1 - 5.4e-05 22.2 0.0 5.4e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral HLH PF00010.26 KFM64531.1 - 3.5e-14 52.5 1.1 7.2e-14 51.5 1.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 KFM64531.1 - 7.8e-09 35.5 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KFM64531.1 - 0.001 19.2 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KFM64531.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold HAUS2 PF15003.6 KFM64531.1 - 0.04 13.6 0.2 0.092 12.5 0.1 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 DUF3776 PF12618.8 KFM64531.1 - 0.044 14.4 1.3 0.07 13.7 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3776) PAS_9 PF13426.7 KFM64531.1 - 0.046 14.0 0.0 0.099 12.9 0.0 1.6 2 0 0 2 2 2 0 PAS domain S-antigen PF05756.11 KFM64531.1 - 0.25 11.7 1.0 0.45 10.9 1.0 1.4 1 0 0 1 1 1 0 S-antigen protein PAS_11 PF14598.6 KFM64532.1 - 5.6e-26 90.9 0.3 1e-25 90.0 0.3 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KFM64532.1 - 2.2e-19 69.5 0.0 3.5e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KFM64532.1 - 5.9e-08 32.9 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KFM64532.1 - 3.3e-07 30.3 0.0 7.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFM64532.1 - 0.0022 18.2 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold 7tm_1 PF00001.21 KFM64533.1 - 1.6e-26 93.2 10.5 2.8e-26 92.4 10.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 KFM64535.1 - 1.9e-13 49.9 10.4 1.4e-10 40.7 7.3 1.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM64535.1 - 4.2e-12 46.1 13.2 2.5e-07 30.9 1.5 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM64535.1 - 2.4e-07 30.3 2.8 0.0021 18.0 0.1 3.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 KFM64535.1 - 9e-06 25.6 6.1 0.38 11.5 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.6 KFM64535.1 - 0.0067 15.9 0.3 0.0075 15.8 0.3 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.6 KFM64535.1 - 0.0095 15.9 0.4 0.011 15.7 0.4 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFM64537.1 - 4.6e-08 32.5 4.4 4.6e-08 32.5 4.4 1.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM64538.1 - 3.6e-16 59.2 3.0 6.3e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64538.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64538.1 - 3.1e-07 30.0 1.6 7.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64538.1 - 0.003 17.3 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64538.1 - 3 8.5 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain 7tm_1 PF00001.21 KFM64539.1 - 3.4e-18 65.9 7.0 4.3e-18 65.6 7.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFM64539.1 - 0.013 15.3 4.7 0.015 15.0 4.7 1.0 1 0 0 1 1 1 0 Olfactory receptor LRR19-TM PF15176.6 KFM64539.1 - 0.062 13.3 0.2 0.092 12.7 0.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain 7tm_1 PF00001.21 KFM64540.1 - 1.5e-08 34.3 5.4 2.1e-08 33.8 5.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Claudin_2 PF13903.6 KFM64543.1 - 4.2e-08 33.2 0.1 5.9e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFM64543.1 - 5.7e-07 29.6 0.2 6.2e-07 29.4 0.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 KFM64543.1 - 0.00026 21.2 0.3 0.00027 21.2 0.3 1.2 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 KFM64543.1 - 0.008 15.7 0.2 0.0099 15.4 0.2 1.1 1 0 0 1 1 1 1 Clc-like Phage_30_3 PF08010.11 KFM64543.1 - 0.19 11.5 0.6 0.66 9.8 0.2 1.8 1 1 0 2 2 2 0 Bacteriophage protein GP30.3 Claudin_2 PF13903.6 KFM64544.1 - 4.9e-27 94.9 6.9 6.4e-27 94.6 6.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 KFM64544.1 - 7.8e-07 29.5 5.8 9.1e-07 29.2 3.9 1.8 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 KFM64544.1 - 1.2e-06 28.5 4.0 0.0048 16.8 2.2 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 KFM64544.1 - 0.0017 18.3 6.8 0.0036 17.3 6.9 1.5 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF4064 PF13273.6 KFM64544.1 - 0.011 16.0 8.2 5.6 7.3 0.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) AC_N PF16214.5 KFM64544.1 - 0.12 11.5 0.9 0.16 11.0 0.9 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region PfkB PF00294.24 KFM64545.1 - 3.5e-10 39.7 0.0 6.3e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase OST-HTH PF12872.7 KFM64546.1 - 8.1e-07 28.8 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain YTV PF07639.11 KFM64546.1 - 0.00011 22.2 10.4 0.0014 18.7 1.1 3.0 2 1 1 3 3 3 2 YTV dsrm PF00035.26 KFM64546.1 - 0.12 13.1 0.2 0.48 11.2 0.2 2.1 1 0 0 1 1 1 0 Double-stranded RNA binding motif MFS_1 PF07690.16 KFM64549.1 - 1.6e-42 145.7 22.2 6e-36 124.1 15.8 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Clc-like PF07062.12 KFM64549.1 - 0.36 10.3 7.9 2 7.9 2.6 2.6 2 0 0 2 2 2 0 Clc-like DDHD PF02862.17 KFM64550.1 - 9.2e-53 179.7 0.3 7.6e-52 176.7 0.0 2.3 2 0 0 2 2 2 1 DDHD domain SAM_1 PF00536.30 KFM64550.1 - 8.1e-11 42.2 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WWE PF02825.20 KFM64550.1 - 7.1e-08 32.9 1.3 0.0065 17.0 0.0 2.8 1 1 1 2 2 2 2 WWE domain SAM_2 PF07647.17 KFM64550.1 - 3.2e-05 24.0 0.0 7.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HTH_Tnp_Tc3_2 PF01498.18 KFM64551.1 - 2.4e-16 59.7 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64551.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1943 PF09172.11 KFM64554.1 - 1.9e-08 33.9 0.1 2e-08 33.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) DUF3397 PF11877.8 KFM64554.1 - 0.09 13.0 0.0 0.091 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) DUF1758 PF05585.12 KFM64555.1 - 0.035 13.9 0.2 0.04 13.7 0.2 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Antimicrobial18 PF08130.11 KFM64556.1 - 0.074 13.1 0.2 19 5.5 0.0 3.4 3 0 0 3 3 3 0 Type A lantibiotic family AF0941-like PF14591.6 KFM64557.1 - 0.011 16.3 7.4 2.5 8.7 4.6 3.0 1 1 1 3 3 3 0 AF0941-like DUF4945 PF16303.5 KFM64557.1 - 0.02 14.8 0.8 0.65 9.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4945) mCpol PF18182.1 KFM64557.1 - 0.034 14.5 0.3 0.077 13.3 0.3 1.6 1 0 0 1 1 1 0 minimal CRISPR polymerase domain SapB_1 PF05184.15 KFM64557.1 - 0.073 13.1 1.2 1.3 9.1 0.2 3.2 2 1 0 2 2 2 0 Saposin-like type B, region 1 Condensin2nSMC PF12422.8 KFM64557.1 - 0.11 12.7 1.2 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit NAAA-beta PF15508.6 KFM64557.1 - 0.13 12.5 2.3 1.1 9.6 0.0 3.4 3 2 1 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUP PF00674.18 KFM64557.1 - 1 9.5 3.6 0.42 10.8 0.4 1.9 2 0 0 2 2 2 0 DUP family DUF1081 PF06448.11 KFM64558.1 - 0.0024 18.3 0.1 0.063 13.7 0.0 3.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1081) EF-hand_7 PF13499.6 KFM64559.1 - 1e-10 41.9 6.5 8.6e-05 22.9 1.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM64559.1 - 1.5e-08 33.9 10.4 4.7e-06 26.1 1.5 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KFM64559.1 - 3.2e-08 32.6 3.4 3.9e-06 26.0 1.2 3.5 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 KFM64559.1 - 4.1e-05 22.9 1.1 0.00016 21.0 1.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KFM64559.1 - 0.00076 19.3 9.4 0.042 13.7 0.1 3.6 3 2 1 4 4 4 3 EF-hand domain pair NAM-associated PF14303.6 KFM64559.1 - 3 8.5 10.4 4.6 7.9 10.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Ubiq_cyt_C_chap PF03981.12 KFM64560.1 - 5.4e-21 75.2 0.0 7.3e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone GIIM PF08388.11 KFM64560.1 - 0.11 12.5 0.1 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 Group II intron, maturase-specific domain PXA PF02194.15 KFM64561.1 - 1.4e-07 31.6 1.0 1.4e-07 31.6 1.0 1.8 2 0 0 2 2 2 1 PXA domain CUB PF00431.20 KFM64565.1 - 6.9e-06 26.4 0.1 6.9e-06 26.4 0.1 1.0 1 0 0 1 1 1 1 CUB domain PRIMA1 PF16101.5 KFM64566.1 - 0.00077 19.5 8.1 0.23 11.5 3.1 2.5 2 0 0 2 2 2 2 Proline-rich membrane anchor 1 SieB PF14163.6 KFM64566.1 - 0.028 13.9 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B FAM176 PF14851.6 KFM64566.1 - 0.036 13.7 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 FAM176 family DUF4229 PF14012.6 KFM64566.1 - 0.048 13.8 0.3 0.082 13.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF3040 PF11239.8 KFM64566.1 - 0.16 12.3 0.2 15 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Hydantoinase_B PF02538.14 KFM64567.1 - 2.5e-57 194.5 3.9 2.9e-57 194.3 3.9 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_B PF02538.14 KFM64568.1 - 1.1e-146 489.4 0.0 1.4e-146 489.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KFM64568.1 - 1.8e-106 355.7 0.3 4.5e-106 354.3 0.1 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFM64568.1 - 1.4e-61 207.3 0.1 4.4e-59 199.2 0.0 2.6 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Drc1-Sld2 PF11719.8 KFM64569.1 - 1.2e-09 38.2 11.4 1.2e-09 38.2 11.4 2.2 1 1 0 2 2 2 1 DNA replication and checkpoint protein zf-CCHC PF00098.23 KFM64570.1 - 9e-08 31.9 2.7 9e-08 31.9 2.7 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 KFM64570.1 - 0.00063 19.6 0.7 0.0012 18.8 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM64570.1 - 0.0013 18.4 4.3 0.0025 17.5 4.3 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KFM64570.1 - 0.0053 16.6 3.0 0.0053 16.6 3.0 1.6 2 0 0 2 2 2 1 Zinc knuckle DMSP_lyase PF16867.5 KFM64570.1 - 0.054 13.1 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DEAD PF00270.29 KFM64571.1 - 5.7e-12 45.7 0.0 6.4e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM64571.1 - 0.00062 19.8 0.0 0.00076 19.5 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFM64571.1 - 0.1 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Helicase_C PF00271.31 KFM64572.1 - 2.2e-17 63.4 0.1 1.7e-16 60.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-H2C2_2 PF13465.6 KFM64575.1 - 5.4e-20 70.9 32.9 4.2e-08 33.3 1.1 6.5 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM64575.1 - 4.8e-19 67.4 29.1 0.0047 17.6 0.7 6.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM64575.1 - 9.8e-18 63.5 33.8 0.00011 22.5 1.7 6.1 6 0 0 6 6 5 4 Zinc finger, C2H2 type zf-Di19 PF05605.12 KFM64575.1 - 0.00011 22.4 1.1 0.00011 22.4 1.1 4.0 3 1 0 4 4 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFM64575.1 - 0.0002 21.5 8.0 4.2 7.8 0.0 5.2 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM64575.1 - 0.0006 20.1 17.7 0.43 11.0 2.3 5.4 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-MYST PF17772.1 KFM64575.1 - 0.0034 17.0 4.1 8.8 6.0 0.0 4.4 3 1 1 4 4 4 0 MYST family zinc finger domain TFIIA PF03153.13 KFM64575.1 - 0.0049 16.9 17.9 0.0049 16.9 17.9 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-C2HC_2 PF13913.6 KFM64575.1 - 0.013 15.4 4.2 0.058 13.3 0.7 5.3 4 1 1 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFM64575.1 - 0.023 14.7 21.0 1.5 8.9 0.0 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger BolA PF01722.18 KFM64575.1 - 0.11 12.7 4.6 0.23 11.8 0.3 2.9 2 1 1 3 3 3 0 BolA-like protein zf-C2H2_8 PF15909.5 KFM64575.1 - 0.18 12.1 13.4 0.97 9.8 1.2 3.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon Sprouty PF05210.13 KFM64575.1 - 0.25 11.7 7.2 0.12 12.8 3.9 2.0 2 0 0 2 2 2 0 Sprouty protein (Spry) zf-FCS PF06467.14 KFM64575.1 - 0.41 10.6 11.5 10 6.2 0.0 4.2 3 1 1 4 4 4 0 MYM-type Zinc finger with FCS sequence motif PAT1 PF09770.9 KFM64575.1 - 0.53 8.5 12.6 0.73 8.0 12.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CobT PF06213.12 KFM64575.1 - 1.1 8.6 7.7 1.7 8.0 7.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4175 PF13779.6 KFM64575.1 - 1.1 7.0 14.6 1.6 6.5 14.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) zf-RRPl_C4 PF17026.5 KFM64575.1 - 1.3 9.2 5.3 18 5.4 0.5 3.0 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type EPL1 PF10513.9 KFM64575.1 - 1.4 9.3 10.4 0.35 11.2 5.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF2367 PF10164.9 KFM64575.1 - 2.1 8.9 7.1 9.6 6.8 7.1 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) zf_UBZ PF18439.1 KFM64575.1 - 2.6 7.7 17.4 4.3 7.0 0.0 5.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 KFM64575.1 - 3.8 7.7 17.2 3.6e+03 -1.8 17.5 3.6 1 1 0 1 1 1 0 FYVE zinc finger IRF PF00605.17 KFM64576.1 - 5.9e-10 39.4 0.5 1.8e-09 37.8 0.4 1.8 2 0 0 2 2 2 1 Interferon regulatory factor transcription factor Ets PF00178.22 KFM64576.1 - 0.0018 18.7 0.9 0.0055 17.1 0.9 1.9 1 1 0 1 1 1 1 Ets-domain JmjC PF02373.22 KFM64577.1 - 1.6e-23 83.3 0.6 5.4e-23 81.6 0.1 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 KFM64577.1 - 8.8e-18 64.0 3.1 2.2e-17 62.7 3.1 1.7 1 0 0 1 1 1 1 jmjN domain ARID PF01388.21 KFM64577.1 - 9.5e-13 48.6 0.1 2.1e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 KFM64577.1 - 2.5e-08 34.2 6.6 7e-08 32.7 6.6 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger DUF1295 PF06966.12 KFM64579.1 - 5e-81 271.7 2.6 5.9e-81 271.4 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KFM64579.1 - 1.2e-07 31.8 0.6 3.6e-07 30.3 0.6 1.9 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KFM64579.1 - 0.00035 20.9 1.5 0.00092 19.6 0.2 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KFM64579.1 - 0.0017 18.8 0.1 0.0017 18.8 0.1 2.3 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2721 PF11026.8 KFM64579.1 - 1.6 8.6 8.9 7.6 6.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Ku PF02735.16 KFM64580.1 - 3.4e-45 154.3 0.2 4.6e-45 153.8 0.2 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KFM64580.1 - 2.3e-22 79.8 1.4 4.3e-22 78.9 1.4 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KFM64580.1 - 2.9e-13 50.3 1.7 7.5e-13 49.0 1.7 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm HTH_Tnp_Tc3_2 PF01498.18 KFM64581.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64581.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64582.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64582.1 - 8.6e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM64583.1 - 2e-14 53.6 0.1 2.6e-13 50.0 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64583.1 - 1.1e-10 41.6 1.0 2.7e-10 40.3 1.0 1.7 1 0 0 1 1 1 1 Transposase DUF4371 PF14291.6 KFM64584.1 - 8.9e-10 38.6 0.1 3.2e-09 36.8 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM64584.1 - 0.0041 16.7 0.4 0.0041 16.7 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger C2H2-type DUF4196 PF13846.6 KFM64584.1 - 0.14 12.4 0.1 9.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) SAP PF02037.27 KFM64585.1 - 4.5e-09 35.9 0.2 1.1e-08 34.6 0.2 1.7 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KFM64585.1 - 9.3e-05 22.2 0.4 0.0008 19.2 0.3 2.4 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain UNC-93 PF05978.16 KFM64586.1 - 5e-07 29.6 9.7 5e-07 29.6 9.7 3.5 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFM64586.1 - 6.2e-06 25.4 44.0 0.00025 20.1 10.0 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF5337 PF17272.2 KFM64586.1 - 0.17 11.7 1.2 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Pox_A14 PF05767.12 KFM64586.1 - 1.1 9.5 6.7 6.5 7.0 0.6 3.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 CactinC_cactus PF09732.9 KFM64587.1 - 3.8e-11 43.0 2.1 6.8e-11 42.2 2.1 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Phage_XkdX PF09693.10 KFM64587.1 - 0.012 15.6 0.3 5.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) DUF4222 PF13973.6 KFM64590.1 - 0.041 13.5 0.2 0.084 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4222) CPG4 PF15481.6 KFM64590.1 - 0.99 10.1 6.2 0.19 12.3 2.3 1.9 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 zf-H2C2_2 PF13465.6 KFM64591.1 - 1.2e-31 107.7 33.6 4.7e-08 33.1 1.6 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64591.1 - 1.6e-18 66.0 47.2 1.2e-06 28.6 0.6 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64591.1 - 3.6e-13 49.1 42.3 0.00036 21.1 0.2 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM64591.1 - 0.00016 21.4 24.6 0.00091 18.9 0.1 5.2 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM64591.1 - 0.0005 19.8 51.8 0.0041 16.8 2.5 6.2 5 2 0 5 5 5 3 C2H2-type zinc-finger domain FYDLN_acid PF09538.10 KFM64591.1 - 0.0014 19.3 5.3 0.28 11.9 0.2 3.2 1 1 0 2 2 2 1 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.12 KFM64591.1 - 0.0014 18.9 22.8 0.0034 17.6 8.7 3.3 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KFM64591.1 - 0.0088 16.1 3.8 0.0088 16.1 3.8 3.9 3 2 2 5 5 5 1 Zinc ribbon domain zf-RING_7 PF02591.15 KFM64591.1 - 0.04 14.1 8.5 18 5.6 0.1 4.2 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-C2H2_2 PF12756.7 KFM64591.1 - 0.043 14.2 4.4 0.043 14.2 4.4 4.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) PhnA_Zn_Ribbon PF08274.12 KFM64591.1 - 0.081 12.9 4.4 0.46 10.5 0.1 3.4 3 1 0 3 3 3 0 PhnA Zinc-Ribbon zinc_ribbon_15 PF17032.5 KFM64591.1 - 0.21 12.3 16.6 0.14 12.9 2.3 2.8 1 1 2 3 3 3 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KFM64591.1 - 0.34 10.4 7.6 2.1 7.9 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_jaz PF12171.8 KFM64591.1 - 0.37 11.2 22.0 1.4 9.3 1.9 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM64591.1 - 0.44 10.6 0.1 0.44 10.6 0.1 5.7 5 2 0 5 5 5 0 C2H2-type zinc finger zf_UBZ PF18439.1 KFM64591.1 - 0.56 9.9 17.7 0.59 9.8 0.1 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF3268 PF11672.8 KFM64591.1 - 0.82 10.0 12.5 0.44 10.9 0.7 2.6 2 1 1 3 3 3 0 zinc-finger-containing domain zf-trcl PF13451.6 KFM64591.1 - 1.2 9.0 23.2 27 4.8 2.6 4.7 2 2 1 3 3 3 0 Probable zinc-ribbon domain HalOD2 PF18547.1 KFM64591.1 - 2.4 8.1 17.3 0.098 12.6 3.3 3.6 4 1 0 4 4 3 0 Halobacterial output domain 2 zinc_ribbon_5 PF13719.6 KFM64591.1 - 2.5 7.9 12.9 37 4.2 0.2 4.1 3 1 0 3 3 3 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KFM64591.1 - 2.7 7.7 14.8 3.7 7.3 0.1 4.6 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_SprT PF17283.2 KFM64591.1 - 2.8 7.9 23.8 1.4 8.9 7.1 4.3 3 2 0 3 3 3 0 SprT-like zinc ribbon domain zf-AN1 PF01428.16 KFM64591.1 - 3 8.1 28.2 0.68 10.2 1.3 5.0 3 1 2 5 5 5 0 AN1-like Zinc finger DUF2256 PF10013.9 KFM64591.1 - 6.7 6.9 18.1 6.9 6.9 0.1 4.2 5 0 0 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_4 PF07975.12 KFM64591.1 - 8 6.8 25.7 0.21 11.8 5.6 3.9 1 1 0 3 3 3 0 TFIIH C1-like domain DDE_3 PF13358.6 KFM64592.1 - 5.5e-16 58.6 0.1 6.3e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64592.1 - 7.5e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM64592.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM64592.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM64592.1 - 0.033 14.2 2.6 0.036 14.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix SCAN PF02023.17 KFM64593.1 - 2.2e-07 30.6 0.1 3.2e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 SCAN domain HTH_Tnp_Tc3_2 PF01498.18 KFM64594.1 - 1.7e-16 60.2 2.6 4.8e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64594.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64595.1 - 2.1e-16 59.9 2.2 6.4e-16 58.4 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64595.1 - 1.5e-13 50.7 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64595.1 - 3.2e-07 30.0 1.6 7.8e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64595.1 - 0.0029 17.3 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64595.1 - 2.8 8.6 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64596.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64596.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64597.1 - 3.1e-17 62.6 2.8 6e-16 58.4 2.2 2.6 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM64597.1 - 1.4e-13 50.8 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64597.1 - 2.1e-07 30.6 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64597.1 - 0.0028 17.4 0.6 0.008 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64597.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64598.1 - 2.5e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64598.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RGS_DHEX PF18148.1 KFM64600.1 - 4.9e-44 148.5 0.7 1.1e-43 147.4 0.7 1.6 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFM64600.1 - 1.1e-33 116.0 0.3 2.8e-33 114.7 0.0 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KFM64600.1 - 3.7e-16 58.9 0.0 1.5e-15 56.9 0.0 2.2 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFM64600.1 - 2e-09 37.3 0.0 5.6e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 GGL domain DUF1514 PF07438.11 KFM64600.1 - 0.2 11.6 0.2 0.47 10.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) Period_C PF12114.8 KFM64601.1 - 9.2 5.8 8.1 12 5.4 8.1 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region GST_N_3 PF13417.6 KFM64602.1 - 1.8e-18 66.7 0.1 2.9e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFM64602.1 - 4.7e-17 62.1 0.1 9.3e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFM64602.1 - 2e-16 60.1 0.0 3.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFM64602.1 - 5.5e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM64602.1 - 0.00014 21.8 0.0 0.0004 20.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KFM64602.1 - 0.0012 19.1 0.0 0.011 16.0 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin GST_C PF00043.25 KFM64602.1 - 0.0038 17.4 0.0 0.008 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFM64602.1 - 0.0056 17.0 0.0 0.015 15.6 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein HTH_Tnp_4 PF13613.6 KFM64604.1 - 0.0069 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease E1_DerP2_DerF2 PF02221.15 KFM64605.1 - 4.3e-20 72.5 2.6 4.9e-20 72.3 2.6 1.0 1 0 0 1 1 1 1 ML domain TNFR_c6 PF00020.18 KFM64609.1 - 1.1e-05 25.7 6.0 1.8e-05 25.0 6.0 1.3 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region Hum_adeno_E3A PF05393.11 KFM64609.1 - 0.056 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF5305 PF17231.2 KFM64609.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) MARVEL PF01284.23 KFM64610.1 - 4.3e-11 43.0 12.2 5.7e-11 42.6 12.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF805 PF05656.14 KFM64610.1 - 0.38 11.2 6.4 0.63 10.5 6.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF4149 PF13664.6 KFM64610.1 - 0.42 10.9 9.8 3.1 8.2 6.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF2070 PF09843.9 KFM64610.1 - 3.9 5.6 12.9 4.9 5.3 12.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short PF00106.25 KFM64614.1 - 3.2e-33 114.9 0.0 3.5e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM64614.1 - 7.3e-24 84.6 0.0 8.8e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM64614.1 - 0.00088 19.2 0.0 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 KR domain EcoRI_methylase PF13651.6 KFM64614.1 - 0.11 11.7 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI Acid_PPase PF12689.7 KFM64615.1 - 2.8e-54 183.5 0.0 3.2e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 KFM64615.1 - 4.2e-10 40.0 0.1 3.2e-09 37.1 0.0 1.9 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM64615.1 - 0.00011 22.6 0.0 0.002 18.4 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 KFM64615.1 - 0.0025 17.6 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KFM64615.1 - 0.062 13.7 0.3 4.7 7.6 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase rve_3 PF13683.6 KFM64616.1 - 0.00045 19.9 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 KFM64616.1 - 0.0066 16.6 0.0 0.0093 16.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Amino_oxidase PF01593.24 KFM64620.1 - 3e-19 69.7 0.0 3e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM64620.1 - 2.5e-17 62.9 0.3 4.3e-17 62.1 0.3 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM64620.1 - 5.7e-08 32.7 0.0 5.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM64620.1 - 6.8e-07 28.7 0.0 7.8e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFM64620.1 - 7.3e-06 25.4 0.0 7.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KFM64620.1 - 1.3e-05 24.7 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM64620.1 - 1.8e-05 25.2 0.1 4.3e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM64620.1 - 5.3e-05 22.6 0.1 7e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM64620.1 - 0.00017 20.4 0.1 0.00027 19.8 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KFM64620.1 - 0.0016 17.8 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFM64620.1 - 0.0065 15.6 0.6 0.0081 15.3 0.6 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFM64620.1 - 0.017 14.4 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KFM64620.1 - 0.018 14.1 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KFM64620.1 - 0.078 12.3 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 KFM64620.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase MCRA PF06100.11 KFM64620.1 - 0.087 11.6 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 MCRA family HEPN PF05168.14 KFM64620.1 - 0.089 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 HEPN domain NAD_binding_9 PF13454.6 KFM64620.1 - 0.13 12.2 0.2 0.27 11.2 0.1 1.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KFM64621.1 - 8.9e-19 68.1 0.0 1e-18 67.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Amino_oxidase PF01593.24 KFM64622.1 - 1e-62 212.9 0.0 3.2e-49 168.4 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM64622.1 - 4.8e-15 55.5 0.1 1.9e-14 53.6 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM64622.1 - 0.00019 21.1 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFM64622.1 - 0.00035 19.9 0.2 0.00075 18.8 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM64622.1 - 0.0016 17.6 0.1 0.0023 17.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFM64622.1 - 0.0021 17.3 0.0 0.0068 15.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM64622.1 - 0.0047 16.2 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KFM64622.1 - 0.029 14.9 0.4 0.091 13.3 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM64622.1 - 0.049 12.3 0.0 0.079 11.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GBP PF02263.19 KFM64623.1 - 1.8e-96 322.4 0.0 2.6e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KFM64623.1 - 0.0002 20.9 0.3 0.00036 20.0 0.3 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 KFM64623.1 - 0.0045 17.3 0.2 0.014 15.8 0.0 1.9 2 0 0 2 2 2 1 T-lymphoma invasion and metastasis CC-Ex domain DUF2652 PF10851.8 KFM64625.1 - 0.034 14.3 0.3 0.037 14.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) Pneumo_M2 PF07380.11 KFM64625.1 - 0.05 13.9 0.1 0.057 13.7 0.1 1.1 1 0 0 1 1 1 0 Pneumovirus M2 protein CutA1 PF03091.15 KFM64626.1 - 0.027 14.3 0.4 0.036 13.9 0.4 1.2 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein HTH_Tnp_Tc3_2 PF01498.18 KFM64627.1 - 5.1e-16 58.7 3.5 6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64627.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64627.1 - 2.1e-07 30.6 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64627.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64627.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64628.1 - 4.9e-16 58.7 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64628.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64628.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64628.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64628.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64629.1 - 5e-16 58.7 3.5 6.1e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64629.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64629.1 - 2.3e-07 30.5 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64629.1 - 0.0029 17.4 0.6 0.008 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64629.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain YL1_C PF08265.11 KFM64630.1 - 1.6e-13 50.1 0.0 2.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain tRNA-synt_1g PF09334.11 KFM64631.1 - 3.7e-73 246.5 0.7 1.9e-71 240.9 0.7 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFM64631.1 - 3.3e-12 45.5 0.5 1.6e-09 36.6 0.2 3.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KFM64631.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFM64632.1 - 5.9e-09 35.2 0.0 9.3e-09 34.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFM64632.1 - 0.00051 20.0 0.1 0.0048 16.9 0.0 2.0 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA DUF3678 PF12435.8 KFM64632.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Pkinase_Tyr PF07714.17 KFM64634.1 - 3.1e-18 66.0 0.1 3.3e-18 65.9 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM64634.1 - 3.2e-05 23.4 0.0 3.2e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM64635.1 - 3e-13 49.7 0.2 4e-13 49.3 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM64635.1 - 2.1e-11 43.7 0.1 2.6e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM64636.1 - 4.4e-44 150.7 0.1 9.2e-44 149.7 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM64636.1 - 7.3e-17 61.6 0.0 1.2e-16 60.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFM64636.1 - 0.017 14.5 0.1 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Jak1_Phl PF17887.1 KFM64637.1 - 6.7e-05 22.9 0.0 9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Jak1 pleckstrin homology-like domain FERM_F1 PF18379.1 KFM64639.1 - 4.6e-12 45.8 0.0 5.2e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 FERM F1 ubiquitin-like domain Na_Ca_ex PF01699.24 KFM64640.1 - 1.6e-25 89.8 16.7 1.8e-25 89.7 16.7 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein HTH_Tnp_Tc3_2 PF01498.18 KFM64642.1 - 5.1e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64642.1 - 4.5e-14 52.4 0.0 7.9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64642.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64642.1 - 0.0029 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64642.1 - 0.032 14.4 0.4 0.091 12.9 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM64642.1 - 2.8 8.6 14.8 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF19 PF01579.18 KFM64643.1 - 0.0053 16.6 5.7 0.0086 15.9 5.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF19) RGM_N PF06535.12 KFM64643.1 - 0.14 12.4 4.6 0.31 11.2 0.4 2.2 1 1 0 2 2 2 0 Repulsive guidance molecule (RGM) N-terminus Occludin_ELL PF07303.13 KFM64644.1 - 0.011 16.5 3.6 0.072 13.8 1.4 2.2 1 1 1 2 2 2 0 Occludin homology domain HTH_Tnp_Tc3_2 PF01498.18 KFM64646.1 - 9.9e-13 48.1 3.5 2.3e-12 47.0 3.5 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64646.1 - 2.3e-12 46.9 0.0 7.6e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64646.1 - 0.027 15.1 0.4 0.027 15.1 0.4 2.1 2 0 0 2 2 2 0 Homeodomain-like domain RT_RNaseH_2 PF17919.1 KFM64647.1 - 1e-30 105.7 0.0 4.8e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM64647.1 - 2.7e-29 101.5 0.0 1.4e-28 99.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM64647.1 - 2.1e-28 99.4 0.1 5.6e-28 98.0 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM64647.1 - 2e-18 66.7 0.0 3.6e-17 62.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM64647.1 - 2.1e-16 59.7 0.0 7.7e-16 58.0 0.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain Arc_C PF18162.1 KFM64647.1 - 3.7e-05 23.5 1.7 0.00013 21.7 0.4 2.7 3 0 0 3 3 3 1 Arc C-lobe zf-H2C2 PF09337.10 KFM64647.1 - 0.0016 18.7 0.0 0.004 17.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM64647.1 - 0.02 15.1 2.8 0.23 11.8 0.0 3.8 3 0 0 3 3 3 0 Retrotransposon gag protein DUF19 PF01579.18 KFM64649.1 - 0.04 13.7 14.5 0.089 12.6 14.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF19) DUF4723 PF15851.5 KFM64649.1 - 0.75 10.0 6.3 1.2 9.3 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4723) DUF19 PF01579.18 KFM64650.1 - 0.015 15.1 13.1 0.021 14.6 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF19) HTH_Tnp_Tc3_2 PF01498.18 KFM64653.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64653.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 KFM64654.1 - 1e-18 67.6 0.1 1.3e-18 67.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM64654.1 - 6.1e-10 38.8 0.2 7.5e-10 38.5 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KFM64654.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 HTH_32 PF13565.6 KFM64655.1 - 0.00016 22.2 0.0 0.00036 21.1 0.0 1.7 1 1 0 1 1 1 1 Homeodomain-like domain HTH_48 PF17906.1 KFM64655.1 - 0.0004 20.5 0.0 0.00078 19.5 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_Tc3_2 PF01498.18 KFM64657.1 - 6.1e-12 45.6 1.2 9.7e-12 45.0 1.2 1.3 1 0 0 1 1 1 1 Transposase CDRN PF05174.12 KFM64657.1 - 0.035 13.8 0.4 0.086 12.6 0.4 1.7 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus RC-P840_PscD PF10657.9 KFM64657.1 - 0.087 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD PseudoU_synth_1 PF01416.20 KFM64658.1 - 4.7e-14 52.8 0.0 7.6e-11 42.4 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2205 PF10224.9 KFM64658.1 - 0.11 12.5 1.5 0.21 11.6 0.4 2.0 2 0 0 2 2 2 0 Short coiled-coil protein APG6_N PF17675.1 KFM64659.1 - 2.1 8.9 66.1 0.027 15.0 16.1 4.6 1 1 2 4 4 4 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KFM64659.1 - 2.4 8.4 58.8 0.22 11.8 10.3 5.5 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.8 KFM64659.1 - 2.6 5.4 48.3 0.0066 14.0 22.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) EzrA PF06160.12 KFM64659.1 - 2.8 6.0 56.4 0.028 12.6 25.7 2.5 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA GrpE PF01025.19 KFM64660.1 - 0.017 14.8 6.7 0.017 14.8 6.7 3.1 2 1 1 3 3 3 0 GrpE TPR_MLP1_2 PF07926.12 KFM64660.1 - 0.018 15.1 13.2 0.018 15.1 13.2 3.2 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 KFM64660.1 - 0.18 12.2 21.4 0.37 11.2 5.8 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF948 PF06103.11 KFM64660.1 - 0.24 11.7 8.1 2.2 8.6 0.2 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HMMR_N PF15905.5 KFM64660.1 - 0.36 10.2 30.4 3.3 7.1 2.4 2.8 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal AcylCoA_dehyd_C PF12186.8 KFM64660.1 - 0.43 10.7 7.4 0.1 12.7 2.5 2.4 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal HAUS2 PF15003.6 KFM64660.1 - 0.5 10.1 11.8 0.15 11.8 6.4 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 NPV_P10 PF05531.12 KFM64660.1 - 0.6 10.6 9.5 6.4 7.3 4.8 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 KFM64660.1 - 0.7 10.6 19.2 2.2 9.0 0.4 4.3 2 1 0 2 2 2 0 SlyX TMF_DNA_bd PF12329.8 KFM64660.1 - 0.91 9.6 33.5 0.13 12.3 3.0 4.1 2 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF489 PF04356.12 KFM64660.1 - 0.94 9.5 9.8 0.74 9.8 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF489) Lebercilin PF15619.6 KFM64660.1 - 0.99 9.0 31.3 0.82 9.3 3.4 3.4 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Phage_GPO PF05929.11 KFM64660.1 - 1.7 8.2 16.4 0.63 9.6 10.0 2.2 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.11 KFM64660.1 - 2.1 7.2 24.0 0.72 8.7 14.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 KFM64660.1 - 2.2 9.0 21.6 3.7 8.3 1.9 3.5 2 1 1 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 KFM64660.1 - 5.7 7.0 13.7 2.2 8.4 5.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5320 PF17253.2 KFM64660.1 - 7.8 7.6 13.5 0.86 10.7 0.3 3.6 3 2 1 4 4 4 0 Family of unknown function (DUF5320) NCD1 PF04904.13 KFM64662.1 - 1.5e-44 149.9 0.1 3.2e-44 148.8 0.1 1.6 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) NCD2 PF04905.13 KFM64662.1 - 0.00057 19.8 4.2 0.0017 18.4 4.2 1.9 1 1 0 1 1 1 1 NAB conserved region 2 (NCD2) TFIIA PF03153.13 KFM64662.1 - 0.03 14.3 44.6 0.039 13.9 44.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 KFM64662.1 - 0.03 12.9 13.8 0.037 12.6 13.8 1.1 1 0 0 1 1 1 0 Macoilin family LMBR1 PF04791.16 KFM64662.1 - 0.26 10.2 0.8 0.26 10.1 0.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1387 PF07139.11 KFM64662.1 - 0.82 9.3 16.2 1.1 9.0 16.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TCP PF03634.13 KFM64662.1 - 0.86 10.2 16.6 1.3 9.6 16.6 1.2 1 0 0 1 1 1 0 TCP family transcription factor Presenilin PF01080.17 KFM64662.1 - 1.1 8.0 21.6 1.4 7.6 21.6 1.1 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 KFM64662.1 - 1.2 7.5 2.3 1.3 7.4 2.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2828 PF11443.8 KFM64662.1 - 2.1 6.3 12.9 2.6 6.0 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FAM60A PF15396.6 KFM64662.1 - 2.2 8.2 15.2 3.1 7.8 15.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 KFM64662.1 - 2.3 8.0 17.5 3.1 7.6 17.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 KFM64662.1 - 2.4 7.1 16.8 3 6.7 16.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 KFM64662.1 - 4 7.1 13.8 5.4 6.7 13.8 1.2 1 0 0 1 1 1 0 Connexin PAT1 PF09770.9 KFM64662.1 - 5 5.3 37.9 6.2 5.0 37.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 KFM64662.1 - 5.5 6.4 19.3 7.4 5.9 19.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CDC45 PF02724.14 KFM64662.1 - 6.3 5.0 13.1 8.3 4.6 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NST1 PF13945.6 KFM64662.1 - 6.4 6.8 23.7 9.6 6.3 23.7 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator SLC12 PF03522.15 KFM64662.1 - 6.5 5.7 18.5 8.5 5.3 18.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SOG2 PF10428.9 KFM64662.1 - 6.8 5.8 25.3 8.1 5.5 25.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CPSF100_C PF13299.6 KFM64662.1 - 7.4 6.7 11.6 12 6.0 11.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal HTH_Tnp_Tc3_2 PF01498.18 KFM64665.1 - 3.9e-16 59.1 3.4 5.2e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64665.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64665.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64665.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64665.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64666.1 - 4.7e-16 58.8 3.5 5.6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64666.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64666.1 - 4.9e-06 26.2 0.8 2.1e-05 24.2 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64666.1 - 0.045 13.5 0.3 0.14 12.0 0.3 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM64666.1 - 5.3 7.7 15.1 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Myb_DNA-bind_5 PF13873.6 KFM64667.1 - 1.4e-10 41.1 1.4 1.4e-10 41.1 1.4 1.9 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFM64667.1 - 0.00062 20.1 3.0 0.00062 20.1 3.0 2.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KFM64667.1 - 0.026 14.7 0.2 0.062 13.5 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-H2C2_2 PF13465.6 KFM64668.1 - 2.9e-17 62.2 10.9 1.2e-09 38.1 1.2 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64668.1 - 5.4e-09 36.0 11.6 3.6e-05 24.0 3.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64668.1 - 6.7e-08 32.7 10.5 0.0018 19.0 1.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM64668.1 - 4.1e-06 26.5 4.7 0.004 16.9 1.2 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM64668.1 - 0.00013 21.9 6.8 0.012 15.6 0.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger GAGA PF09237.11 KFM64668.1 - 0.00067 19.4 0.6 0.0089 15.8 0.2 1.9 1 1 1 2 2 2 1 GAGA factor zf-C2H2_9 PF16293.5 KFM64668.1 - 0.0026 17.6 2.3 0.17 11.8 0.1 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM64668.1 - 0.0041 17.8 1.1 0.0044 17.8 1.1 1.1 1 0 0 1 1 1 1 zinc-ribbon family zf-C2HC_2 PF13913.6 KFM64668.1 - 0.01 15.7 3.9 0.74 9.8 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type BolA PF01722.18 KFM64668.1 - 0.012 15.9 0.4 2.1 8.7 0.0 2.0 1 1 1 2 2 2 0 BolA-like protein zf-met PF12874.7 KFM64668.1 - 0.012 16.0 10.6 0.024 15.0 2.0 2.5 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-DBF PF07535.12 KFM64668.1 - 0.016 15.3 4.9 0.61 10.2 0.3 2.4 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_2 PF12756.7 KFM64668.1 - 0.024 15.0 8.7 0.32 11.4 2.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 KFM64668.1 - 0.037 14.5 10.2 0.15 12.5 0.6 2.6 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2256 PF10013.9 KFM64668.1 - 0.047 13.8 0.4 8.6 6.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) RecR PF02132.15 KFM64668.1 - 0.048 13.2 3.4 0.13 11.8 3.4 1.7 1 1 0 1 1 1 0 RecR protein zf-H2C2_5 PF13909.6 KFM64668.1 - 0.053 13.3 7.6 0.33 10.7 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-MYST PF17772.1 KFM64668.1 - 0.092 12.4 2.1 3.7 7.2 0.1 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain zf-HIT PF04438.16 KFM64668.1 - 0.1 12.5 3.0 5 7.1 0.3 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2_jaz PF12171.8 KFM64668.1 - 0.15 12.4 0.5 0.15 12.4 0.5 2.5 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.21 KFM64668.1 - 0.18 11.9 6.9 1.5 9.0 6.9 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-H2C2_2 PF13465.6 KFM64669.1 - 2.4e-75 245.8 60.1 1.1e-09 38.3 1.6 9.1 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64669.1 - 2.8e-45 150.3 80.1 1.4e-06 28.4 0.5 9.8 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64669.1 - 1.9e-31 106.0 72.8 0.00018 22.1 1.7 9.8 10 0 0 10 10 10 8 C2H2-type zinc finger zf-met PF12874.7 KFM64669.1 - 4.6e-24 84.0 67.2 0.00033 20.9 1.3 9.3 9 0 0 9 9 9 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM64669.1 - 3e-21 74.9 70.0 5e-05 23.2 0.5 9.8 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM64669.1 - 1.1e-13 50.7 54.0 0.012 15.4 2.1 9.2 9 0 0 9 9 9 7 C2H2-type zinc-finger domain zf-MYST PF17772.1 KFM64669.1 - 1.6e-10 40.4 40.4 0.25 11.0 0.1 8.3 3 1 6 9 9 8 6 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 KFM64669.1 - 2e-10 40.5 25.1 1.5 8.9 0.1 8.8 4 2 5 9 9 9 3 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KFM64669.1 - 2.6e-10 40.3 52.3 0.16 12.3 0.8 9.5 9 1 0 9 9 9 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM64669.1 - 3.3e-10 40.1 7.7 0.038 14.3 0.1 5.4 1 1 3 5 5 5 4 BolA-like protein Zf_RING PF16744.5 KFM64669.1 - 7.4e-06 26.0 38.6 0.32 11.2 0.3 8.6 1 1 7 8 8 8 2 KIAA1045 RING finger zf_UBZ PF18439.1 KFM64669.1 - 5.6e-05 22.7 36.1 0.81 9.3 0.2 9.0 9 0 0 9 9 9 3 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KFM64669.1 - 0.00011 21.9 33.0 4.4 7.2 0.2 8.2 2 1 6 8 8 8 1 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM64669.1 - 0.00053 19.7 16.1 0.11 12.4 0.2 6.1 1 1 8 9 9 9 2 GAGA factor NusB PF01029.18 KFM64669.1 - 0.0016 18.7 0.0 22 5.3 0.0 3.5 1 1 1 3 3 3 0 NusB family zf-C2H2_11 PF16622.5 KFM64669.1 - 0.0017 18.0 51.4 0.022 14.5 0.8 9.0 9 0 0 9 9 9 3 zinc-finger C2H2-type Tox-HNH-HHH PF15637.6 KFM64669.1 - 0.0046 17.1 2.6 1.1 9.4 0.0 3.2 1 1 3 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zinc_ribbon_15 PF17032.5 KFM64669.1 - 0.0054 17.5 36.2 0.12 13.2 1.4 5.0 1 1 1 4 4 4 2 zinc-ribbon family Complex1_49kDa PF00346.19 KFM64669.1 - 0.006 15.7 3.0 2.8 7.0 0.1 3.0 1 1 2 3 3 3 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Imm25 PF15564.6 KFM64669.1 - 0.02 14.8 0.3 20 5.1 0.0 4.2 1 1 3 4 4 4 0 Immunity protein 25 DrsE PF02635.15 KFM64669.1 - 0.021 15.2 2.9 11 6.5 0.0 4.5 2 2 2 5 5 4 0 DsrE/DsrF-like family zf-C2H2_2 PF12756.7 KFM64669.1 - 0.023 15.0 59.9 0.8 10.1 0.3 8.3 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) SspN PF08177.11 KFM64669.1 - 0.064 13.2 1.6 7.2 6.7 0.3 4.3 5 0 0 5 5 5 0 Small acid-soluble spore protein N family DUF2256 PF10013.9 KFM64669.1 - 0.075 13.2 31.8 36 4.6 0.8 8.8 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.10 KFM64669.1 - 0.12 12.6 33.5 0.43 10.7 2.8 6.1 3 3 2 6 6 6 0 Zinc ribbon domain zf-FPG_IleRS PF06827.14 KFM64669.1 - 0.12 12.2 26.3 13 5.7 0.1 8.3 9 0 0 9 9 9 0 Zinc finger found in FPG and IleRS Amidohydro_1 PF01979.20 KFM64669.1 - 1.4 8.1 10.5 1.4 8.2 1.2 3.7 1 1 2 3 3 3 0 Amidohydrolase family zf-RRPl_C4 PF17026.5 KFM64669.1 - 1.7 8.8 34.9 0.84 9.8 7.6 4.2 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type TRAF6_Z2 PF18048.1 KFM64669.1 - 2 8.6 41.6 1.4 9.1 0.1 8.5 9 0 0 9 9 9 0 TNF receptor-associated factor 6 zinc finger 2 SPARC_Ca_bdg PF10591.9 KFM64669.1 - 2.3 8.6 7.5 0.55 10.6 0.2 3.3 2 2 3 5 5 3 0 Secreted protein acidic and rich in cysteine Ca binding region PHD PF00628.29 KFM64669.1 - 2.7 8.0 41.4 1.7 8.6 5.4 6.7 4 2 2 6 6 6 0 PHD-finger zf-trcl PF13451.6 KFM64669.1 - 4.5 7.3 35.0 36 4.3 0.1 8.6 8 1 0 8 8 8 0 Probable zinc-ribbon domain zf-H2C2_2 PF13465.6 KFM64670.1 - 2.6e-77 252.1 84.6 5.1e-09 36.2 0.9 12.0 13 0 0 13 13 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64670.1 - 1.5e-44 148.0 110.2 5.4e-05 23.4 3.3 12.1 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64670.1 - 3.6e-34 114.5 99.4 0.0011 19.7 0.9 12.0 12 0 0 12 12 12 11 C2H2-type zinc finger zf-met PF12874.7 KFM64670.1 - 1.2e-24 85.9 85.7 0.0011 19.3 1.2 12.3 12 0 0 12 12 12 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64670.1 - 1.1e-18 67.0 61.9 0.046 14.0 0.1 11.5 8 3 3 11 11 11 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM64670.1 - 3.1e-18 65.3 79.1 0.01 15.8 1.2 11.8 12 0 0 12 12 11 9 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM64670.1 - 4.1e-08 32.9 42.7 0.28 11.0 0.1 10.6 3 2 9 12 12 11 3 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 KFM64670.1 - 3.4e-07 29.9 59.9 0.27 11.0 2.2 11.2 11 0 0 11 11 11 7 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM64670.1 - 3.7e-05 23.6 33.6 0.63 10.1 1.2 7.5 3 1 5 8 8 8 6 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM64670.1 - 0.002 18.2 1.0 35 4.6 0.0 4.3 1 1 2 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Sec23_Sec24 PF04810.15 KFM64670.1 - 0.0029 17.6 44.7 0.72 10.0 1.5 10.6 9 2 2 11 11 11 1 Sec23/Sec24 zinc finger Ntox34 PF15606.6 KFM64670.1 - 0.0035 17.4 5.2 1 9.5 0.2 5.2 3 2 3 6 6 6 1 Bacterial toxin 34 zinc_ribbon_15 PF17032.5 KFM64670.1 - 0.0058 17.4 39.7 0.63 10.8 1.0 6.1 4 2 1 5 5 5 3 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM64670.1 - 0.0069 16.7 72.4 1 9.7 0.6 10.9 1 1 10 11 11 11 5 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 KFM64670.1 - 0.0092 16.0 15.0 74 3.5 0.0 8.6 10 0 0 10 10 10 0 Zinc-finger domain zf-MYST PF17772.1 KFM64670.1 - 0.012 15.2 41.2 1.5 8.4 0.1 10.2 9 1 2 11 11 11 0 MYST family zinc finger domain zf-Paramyx-P PF13008.7 KFM64670.1 - 0.017 14.6 23.0 0.8 9.2 0.2 8.0 8 0 0 8 8 8 0 Zinc-binding domain of Paramyxoviridae V protein zf-RRPl_C4 PF17026.5 KFM64670.1 - 0.037 14.1 41.4 0.14 12.2 4.5 5.2 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type TRAF6_Z2 PF18048.1 KFM64670.1 - 0.041 14.0 40.2 7.8 6.7 0.1 9.9 10 0 0 10 10 9 0 TNF receptor-associated factor 6 zinc finger 2 FYVE PF01363.21 KFM64670.1 - 0.065 13.4 58.9 0.043 13.9 9.1 6.3 3 1 3 6 6 6 0 FYVE zinc finger BolA PF01722.18 KFM64670.1 - 0.18 12.1 14.7 2.4 8.5 1.1 4.9 2 2 4 6 6 6 0 BolA-like protein C5HCH PF17982.1 KFM64670.1 - 1.5 9.0 48.7 11 6.3 0.6 11.0 10 1 2 12 12 11 0 NSD Cys-His rich domain GAGA PF09237.11 KFM64670.1 - 2.1 8.2 32.1 0.27 11.1 0.6 7.5 2 2 5 8 8 8 0 GAGA factor YyzF PF14116.6 KFM64670.1 - 4.4 7.4 37.0 14 5.8 0.1 9.7 11 0 0 11 11 10 0 YyzF-like protein zf-DBF PF07535.12 KFM64670.1 - 6.4 7.0 44.5 19 5.5 0.7 9.9 11 0 0 11 11 10 0 DBF zinc finger RVT_1 PF00078.27 KFM64671.1 - 9.8e-18 64.5 0.1 1.1e-17 64.3 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CRAL_TRIO PF00650.20 KFM64672.1 - 2.7e-06 27.2 0.0 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Myc-LZ PF02344.15 KFM64674.1 - 0.0079 16.3 2.3 0.012 15.6 2.3 1.3 1 0 0 1 1 1 1 Myc leucine zipper domain Cript PF10235.9 KFM64674.1 - 0.038 14.6 0.8 0.046 14.3 0.8 1.1 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT adh_short PF00106.25 KFM64674.1 - 0.12 11.9 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 short chain dehydrogenase Chitin_bind_4 PF00379.23 KFM64675.1 - 1.1e-10 41.9 6.9 1.1e-10 41.9 6.9 2.9 2 0 0 2 2 2 1 Insect cuticle protein DUF2790 PF10976.8 KFM64675.1 - 0.019 15.0 0.2 0.082 12.9 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) Nse4_C PF08743.10 KFM64675.1 - 0.086 13.1 0.1 0.53 10.6 0.1 2.4 1 0 0 1 1 1 0 Nse4 C-terminal PBP_sp32 PF07222.12 KFM64678.1 - 0.013 14.9 0.2 0.014 14.9 0.2 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Baculo_LEF-10 PF07206.11 KFM64678.1 - 0.095 12.9 1.2 0.12 12.5 1.2 1.2 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) Nairovirus_M PF07948.11 KFM64678.1 - 0.12 10.6 0.4 0.11 10.6 0.4 1.0 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Chitin_bind_4 PF00379.23 KFM64679.1 - 3.9e-12 46.5 10.3 6.3e-12 45.8 10.3 1.4 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM64680.1 - 2.2e-06 28.1 9.8 2.2e-06 28.1 9.8 2.5 3 0 0 3 3 3 1 Insect cuticle protein RVT_1 PF00078.27 KFM64681.1 - 6.3e-24 84.7 0.0 2.3e-23 82.9 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM64681.1 - 1.6e-16 60.2 0.0 1e-15 57.6 0.0 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM64681.1 - 2.7e-07 30.4 0.0 5.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_Tnp_Tc3_2 PF01498.18 KFM64685.1 - 2.1e-16 59.9 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64685.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_32 PF13679.6 KFM64687.1 - 7.2e-13 48.8 7.0 1.8e-11 44.3 7.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 KFM64687.1 - 3.3e-09 36.7 3.1 3.7e-05 23.4 3.1 3.1 1 1 1 2 2 2 2 Methyltransferase TRM13 Methyltransf_31 PF13847.6 KFM64687.1 - 5.7e-09 35.9 0.0 8.9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM64687.1 - 1.6e-05 25.5 0.0 3.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFM64687.1 - 0.00019 21.0 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KFM64687.1 - 0.00057 19.5 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFM64687.1 - 0.017 15.9 0.1 0.042 14.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 KFM64687.1 - 0.017 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 KFM64687.1 - 0.021 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 KFM64687.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DDE_3 PF13358.6 KFM64688.1 - 7e-16 58.3 0.1 7.1e-15 55.0 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64688.1 - 8.6e-16 58.0 6.5 1.7e-15 57.0 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM64688.1 - 0.00082 19.9 1.5 0.00082 19.9 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM64688.1 - 0.012 15.4 0.2 0.45 10.4 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain HTH_7 PF02796.15 KFM64688.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM64688.1 - 0.11 12.5 0.4 0.11 12.5 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix Zona_pellucida PF00100.23 KFM64689.1 - 0.0066 16.3 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64690.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64690.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64690.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64690.1 - 0.0024 17.6 0.6 0.0069 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64690.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM64692.1 - 1.8e-06 27.8 0.4 2e-05 24.4 0.4 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease MCM PF00493.23 KFM64693.1 - 1.5e-97 325.1 0.0 2.4e-97 324.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFM64693.1 - 7.4e-33 113.1 0.2 6e-32 110.2 0.1 2.3 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KFM64693.1 - 2.6e-22 79.0 1.2 6.6e-22 77.7 1.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFM64693.1 - 1.5e-08 35.1 0.0 6e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFM64693.1 - 2e-07 30.6 0.0 7.9e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFM64693.1 - 0.0013 18.7 0.0 0.0042 17.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFM64693.1 - 0.003 17.4 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM64693.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain DTHCT PF08070.11 KFM64693.1 - 0.68 10.7 15.2 1.3 9.7 14.0 2.2 1 1 0 1 1 1 0 DTHCT (NUC029) region Bud13 PF09736.9 KFM64694.1 - 2.1e-20 73.6 9.8 2.1e-20 73.6 9.8 4.7 2 1 3 6 6 6 1 Pre-mRNA-splicing factor of RES complex 7tm_2 PF00002.24 KFM64695.1 - 1.8e-27 96.2 4.2 2.1e-27 96.0 4.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) PSI_8 PF00796.18 KFM64695.1 - 0.044 13.6 0.2 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII Extensin-like_C PF06904.12 KFM64696.1 - 0.022 14.8 0.2 0.024 14.7 0.2 1.0 1 0 0 1 1 1 0 Extensin-like protein C-terminus Glyco_transf_10 PF00852.19 KFM64697.1 - 3.1e-59 199.6 0.8 3.1e-59 199.6 0.8 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFM64697.1 - 6.1e-23 81.4 0.2 6.1e-23 81.4 0.2 2.1 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal Surp PF01805.20 KFM64697.1 - 0.066 13.2 0.5 0.3 11.1 0.5 2.1 1 0 0 1 1 1 0 Surp module THB PF18362.1 KFM64697.1 - 0.085 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Tri-helix bundle domain Root_cap PF06830.11 KFM64697.1 - 0.12 12.5 0.1 0.42 10.8 0.1 1.9 1 0 0 1 1 1 0 Root cap XK-related PF09815.9 KFM64698.1 - 2.3e-88 296.5 26.4 2.6e-88 296.4 26.4 1.0 1 0 0 1 1 1 1 XK-related protein HHH_2 PF12826.7 KFM64699.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Zw10 PF06248.13 KFM64702.1 - 6.6e-33 114.1 2.2 6.6e-33 114.1 2.2 1.6 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 DUF4693 PF15764.5 KFM64702.1 - 0.0058 16.2 0.4 0.01 15.4 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4693) Cauli_AT PF03233.13 KFM64702.1 - 0.34 10.8 4.7 0.17 11.8 1.1 2.2 3 0 0 3 3 3 0 Aphid transmission protein Methyltransf_4 PF02390.17 KFM64704.1 - 3.3e-57 192.7 0.0 4.3e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KFM64704.1 - 0.0024 18.5 0.0 0.0043 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM64704.1 - 0.027 15.2 0.0 0.061 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFM64704.1 - 0.031 13.8 0.0 0.077 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KFM64704.1 - 0.12 13.0 0.0 0.4 11.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DDE_3 PF13358.6 KFM64705.1 - 3.2e-08 33.5 0.3 3.7e-08 33.2 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PAN_1 PF00024.26 KFM64709.1 - 2.5e-06 27.4 0.3 7.1e-06 25.9 0.3 1.7 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.12 KFM64709.1 - 0.0017 18.2 0.1 0.0023 17.7 0.1 1.2 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 KFM64709.1 - 0.33 10.9 4.0 0.15 12.0 1.8 1.8 2 1 0 2 2 2 0 PAN domain MRP-L47 PF06984.13 KFM64710.1 - 2.2e-35 120.6 0.9 5.2e-35 119.4 0.9 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Glyco_hydro_38N PF01074.22 KFM64711.1 - 4.1e-87 292.2 3.4 5.7e-87 291.7 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFM64711.1 - 1.6e-30 106.8 0.0 2.6e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFM64711.1 - 2.5e-24 85.2 0.5 5.9e-24 84.0 0.5 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain RHD_DNA_bind PF00554.22 KFM64713.1 - 1.3e-27 96.8 0.3 1.4e-27 96.7 0.3 1.0 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFM64714.1 - 5.8e-36 122.6 0.1 9.2e-36 122.0 0.1 1.3 1 0 0 1 1 1 1 Rel homology dimerisation domain Axin_b-cat_bind PF08833.10 KFM64714.1 - 5.2 7.3 6.0 13 6.0 6.0 1.7 1 0 0 1 1 1 0 Axin beta-catenin binding domain RHD_DNA_bind PF00554.22 KFM64715.1 - 4.7e-24 85.2 0.2 1.2e-23 83.9 0.1 1.6 1 1 1 2 2 2 1 Rel homology DNA-binding domain FOXO-TAD PF16676.5 KFM64715.1 - 0.22 12.0 0.2 0.4 11.1 0.2 1.4 1 0 0 1 1 1 0 Transactivation domain of FOXO protein family HTH_Tnp_Tc3_2 PF01498.18 KFM64716.1 - 8e-16 58.1 2.2 2.1e-15 56.7 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64716.1 - 4.8e-13 49.1 0.0 1.2e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64716.1 - 1.7e-06 27.7 1.6 2.2e-06 27.3 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64716.1 - 0.01 15.6 0.5 0.024 14.4 0.5 1.7 1 0 0 1 1 1 0 Homeodomain-like domain FERM_M PF00373.18 KFM64718.1 - 7.4e-14 52.2 0.0 1.7e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 FERM central domain Arg_decarb_HB PF17810.1 KFM64718.1 - 0.076 13.3 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Arginine decarboxylase helical bundle domain IRS PF02174.17 KFM64718.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 PTB domain (IRS-1 type) MyTH4 PF00784.17 KFM64719.1 - 2.5e-20 73.0 0.7 5e-20 72.0 0.7 1.6 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 KFM64719.1 - 7.2e-14 52.2 0.0 2.7e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 FERM central domain RA PF00788.23 KFM64719.1 - 0.0031 18.1 0.0 0.0073 16.9 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.10 KFM64719.1 - 0.079 12.9 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 FERM N-terminal domain RIF5_SNase_1 PF18187.1 KFM64719.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 TbRIF5 SNase domain 1 Myosin_head PF00063.21 KFM64720.1 - 1.3e-58 198.9 0.1 1.9e-58 198.3 0.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFM64720.1 - 9.3e-13 46.8 16.3 0.00031 20.3 1.5 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif RRT14 PF17075.5 KFM64720.1 - 0.0074 16.4 5.2 0.023 14.9 5.2 1.8 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 HTH_24 PF13412.6 KFM64720.1 - 0.032 13.8 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Oscp1 PF10188.9 KFM64720.1 - 0.039 14.1 1.0 0.083 13.0 0.2 2.0 2 0 0 2 2 2 0 Organic solute transport protein 1 Myosin_head PF00063.21 KFM64721.1 - 1.6e-28 99.4 0.0 1.7e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_head PF00063.21 KFM64722.1 - 4.1e-42 144.3 0.5 4.3e-42 144.2 0.5 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_6 PF12774.7 KFM64722.1 - 0.004 16.2 0.1 0.0056 15.7 0.1 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region RsgA_GTPase PF03193.16 KFM64722.1 - 0.0065 16.4 0.0 0.0065 16.4 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase TsaE PF02367.17 KFM64722.1 - 0.018 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KFM64722.1 - 0.025 14.9 0.2 0.046 14.0 0.2 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM64722.1 - 0.04 14.4 0.1 0.073 13.6 0.1 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KFM64722.1 - 0.04 14.3 0.0 0.055 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 KFM64722.1 - 0.071 12.0 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain T2SSE PF00437.20 KFM64722.1 - 0.093 11.8 0.1 0.093 11.8 0.1 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KFM64722.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Chitin_bind_4 PF00379.23 KFM64723.1 - 7.7e-09 35.9 2.9 1.6e-08 34.9 2.9 1.6 1 1 0 1 1 1 1 Insect cuticle protein DUF5399 PF17377.2 KFM64723.1 - 0.046 13.5 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5399) Chitin_bind_4 PF00379.23 KFM64724.1 - 4.5e-09 36.7 7.5 7.4e-09 36.0 7.5 1.4 1 0 0 1 1 1 1 Insect cuticle protein HMG_box PF00505.19 KFM64725.1 - 3.3e-18 65.8 1.7 3.3e-18 65.8 1.7 2.7 2 1 1 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM64725.1 - 3.4e-06 27.5 0.7 1.1e-05 25.9 0.7 2.0 1 0 0 1 1 1 1 HMG-box domain DUF2408 PF10303.9 KFM64725.1 - 0.033 14.7 1.5 0.062 13.9 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) YlqD PF11068.8 KFM64725.1 - 6.7 7.1 12.9 1.9 8.9 9.0 2.0 2 0 0 2 2 2 0 YlqD protein CSN4_RPN5_eIF3a PF18420.1 KFM64726.1 - 2e-25 88.7 3.2 2e-25 88.7 3.2 1.9 3 0 0 3 3 3 1 CSN4/RPN5/eIF3a helix turn helix domain PCI PF01399.27 KFM64726.1 - 5e-17 62.3 0.1 9.3e-17 61.5 0.0 1.4 2 0 0 2 2 2 1 PCI domain DUF759 PF05537.11 KFM64726.1 - 0.076 11.9 0.2 0.088 11.7 0.2 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) RPN7 PF10602.9 KFM64727.1 - 0.00041 20.1 1.0 0.00062 19.5 1.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 KFM64727.1 - 0.0043 17.5 1.5 2.8 8.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH_6 PF18585.1 KFM64727.1 - 0.028 14.3 0.2 3.7 7.5 0.0 3.0 3 1 1 4 4 4 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 YscO PF07321.12 KFM64727.1 - 0.048 13.6 0.1 0.048 13.6 0.1 2.2 3 0 0 3 3 3 0 Type III secretion protein YscO TPR_14 PF13428.6 KFM64727.1 - 1.5 9.9 5.7 7 7.8 0.4 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TCR PF03638.15 KFM64728.1 - 4.8e-23 81.2 58.0 1.1e-11 44.8 23.8 2.5 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 KFM64728.1 - 0.061 13.5 46.0 0.19 11.9 18.0 2.6 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 RRM_1 PF00076.22 KFM64729.1 - 3.8e-33 113.1 1.9 4.2e-17 61.7 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM64729.1 - 1e-15 57.6 0.4 3.1e-07 30.4 0.2 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM64729.1 - 1.4e-07 31.4 0.2 0.0054 16.7 0.1 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 KFM64729.1 - 0.00042 20.2 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 RL domain RRM_3 PF08777.11 KFM64729.1 - 0.00085 19.3 3.4 0.091 12.8 0.1 3.0 3 1 0 3 3 3 2 RNA binding motif PHM7_cyt PF14703.6 KFM64729.1 - 0.0011 19.2 0.7 2.5 8.3 0.1 3.7 1 1 3 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter NCBP3 PF10309.9 KFM64729.1 - 0.059 13.2 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Nuclear cap-binding protein subunit 3 DUF4651 PF15513.6 KFM64729.1 - 0.081 12.8 3.2 2.5 8.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4651) DUF616 PF04765.13 KFM64729.1 - 0.12 11.6 0.3 0.19 10.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF616) IRF PF00605.17 KFM64730.1 - 1e-21 77.2 3.1 2.3e-21 76.1 3.1 1.6 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor DUF4604 PF15377.6 KFM64730.1 - 3 8.3 8.0 5.4 7.4 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF155 PF02582.14 KFM64732.1 - 4.4e-08 33.4 0.0 4.7e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Trypsin PF00089.26 KFM64734.1 - 4.6e-27 95.3 0.0 5e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin VLPT PF07122.11 KFM64735.1 - 0.004 16.9 0.2 0.0084 15.8 0.2 1.6 1 0 0 1 1 1 1 Variable length PCR target protein (VLPT) DDE_3 PF13358.6 KFM64736.1 - 2e-11 43.8 0.0 9.1e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64736.1 - 7e-09 35.8 0.2 1.4e-08 34.9 0.2 1.5 1 0 0 1 1 1 1 Transposase COesterase PF00135.28 KFM64737.1 - 8.9e-142 473.5 0.0 1e-141 473.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM64737.1 - 3.7e-12 46.5 0.1 9.4e-12 45.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM64737.1 - 0.013 15.0 0.2 0.032 13.7 0.2 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family DNApol_Exo PF18136.1 KFM64738.1 - 2.5e-24 85.9 0.0 3.4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain Metallophos PF00149.28 KFM64740.1 - 5.2e-14 53.2 4.0 8.3e-14 52.6 4.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Syntaxin PF00804.25 KFM64741.1 - 9e-09 35.3 16.2 1.1e-08 35.0 16.2 1.1 1 0 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 KFM64741.1 - 2.8e-05 24.0 5.0 0.0014 18.5 0.4 2.1 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_pol_alpha_N PF12254.8 KFM64741.1 - 0.071 13.2 1.4 0.21 11.7 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal SbcD_C PF12320.8 KFM64741.1 - 0.25 11.7 4.3 0.24 11.7 0.6 2.3 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain MutS_III PF05192.18 KFM64741.1 - 0.53 10.5 5.7 0.73 10.0 5.7 1.2 1 0 0 1 1 1 0 MutS domain III DUF948 PF06103.11 KFM64741.1 - 0.71 10.2 3.6 8.4 6.7 0.2 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 KFM64741.1 - 1.4 8.4 9.5 1.7 8.1 9.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KFM64741.1 - 2.2 8.3 8.0 9.4 6.3 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 KFM64741.1 - 3 8.6 8.6 79 4.0 0.6 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CENP-H PF05837.12 KFM64741.1 - 3.7 8.0 11.3 8.1 6.9 0.2 2.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Enkurin PF13864.6 KFM64741.1 - 6.2 7.3 9.2 1.1 9.7 1.3 2.6 2 1 1 3 3 3 0 Calmodulin-binding GIT1_C PF12205.8 KFM64741.1 - 8.8 6.5 9.7 1.3 9.2 1.6 2.8 1 1 1 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term HTH_Tnp_Tc3_2 PF01498.18 KFM64743.1 - 2.3e-16 59.8 2.2 4.7e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64743.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_8 PF01501.20 KFM64744.1 - 7.1e-08 32.3 4.6 2.4e-07 30.6 0.8 2.9 2 1 0 2 2 2 1 Glycosyl transferase family 8 DUF3905 PF13045.6 KFM64744.1 - 0.22 11.5 3.8 0.23 11.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3905) fn3 PF00041.21 KFM64745.1 - 3.9e-20 72.0 0.3 3.3e-13 49.8 0.2 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Stevor PF17410.2 KFM64745.1 - 0.00022 20.8 0.1 0.00034 20.2 0.1 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF2569 PF10754.9 KFM64745.1 - 0.012 16.1 0.1 0.02 15.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) I-set PF07679.16 KFM64746.1 - 3.3e-52 174.5 0.0 2.9e-18 65.7 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM64746.1 - 1.5e-47 160.1 0.1 1.8e-14 54.1 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM64746.1 - 7.8e-30 103.1 0.0 2.8e-10 40.4 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM64746.1 - 1.1e-29 102.5 0.0 5.4e-09 36.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM64746.1 - 1.4e-21 76.7 1.5 0.00018 21.7 0.0 5.5 3 3 1 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM64746.1 - 9e-10 38.5 0.6 0.15 12.1 0.0 3.7 2 2 1 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM64746.1 - 6.3e-09 35.3 0.0 0.21 11.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Izumo-Ig PF16706.5 KFM64746.1 - 3.1e-05 23.9 0.0 1.5 8.9 0.0 3.3 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFM64746.1 - 3.4e-05 24.1 0.0 0.71 10.3 0.0 3.5 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFM64746.1 - 0.00022 21.2 0.0 0.37 10.8 0.0 3.2 3 0 0 3 3 3 1 C17orf99 Ig domain C2-set PF05790.15 KFM64746.1 - 0.012 15.8 0.1 8.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Immunoglobulin C2-set domain zf-RRN7 PF11781.8 KFM64746.1 - 0.013 15.2 0.4 12 5.7 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Receptor_2B4 PF11465.8 KFM64746.1 - 0.046 13.9 0.0 8.1 6.7 0.0 2.8 2 1 1 3 3 3 0 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 KFM64746.1 - 0.078 13.0 0.0 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Herpes_gE PF02480.16 KFM64746.1 - 0.088 11.5 0.0 8.5 5.0 0.0 2.6 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E BiPBP_C PF06832.12 KFM64746.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Adeno_E3_CR1 PF02440.15 KFM64746.1 - 0.12 12.1 0.0 3.8 7.4 0.0 2.8 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 CBFD_NFYB_HMF PF00808.23 KFM64750.1 - 9.9e-10 38.6 0.6 2.3e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-H2C2_2 PF13465.6 KFM64751.1 - 7.3e-134 430.8 139.7 5.3e-09 36.1 2.8 20.1 20 0 0 20 20 20 20 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64751.1 - 2.9e-90 292.0 175.3 5e-06 26.7 1.8 20.1 20 0 0 20 20 20 20 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64751.1 - 6e-62 200.9 170.4 0.00081 20.0 2.7 20.1 20 0 0 20 20 20 19 C2H2-type zinc finger zf-met PF12874.7 KFM64751.1 - 8e-38 127.8 155.6 0.0046 17.3 2.8 20.2 20 0 0 20 20 20 18 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM64751.1 - 2.6e-27 94.2 154.8 0.0051 16.8 2.0 20.7 20 1 0 20 20 20 15 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM64751.1 - 3e-24 84.4 90.7 0.0092 15.7 0.1 18.6 19 0 0 19 19 19 11 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM64751.1 - 1.7e-22 79.2 127.4 0.068 13.5 2.5 20.4 20 1 0 20 20 20 10 Zinc-finger double-stranded RNA-binding zf-RRPl_C4 PF17026.5 KFM64751.1 - 1e-09 38.4 93.7 0.037 14.1 6.4 7.6 1 1 6 7 7 7 7 Putative ribonucleoprotein zinc-finger pf C4 type Tox-HNH-HHH PF15637.6 KFM64751.1 - 3.5e-07 30.3 15.5 0.83 9.8 0.0 8.0 1 1 6 9 9 9 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Sec23_Sec24 PF04810.15 KFM64751.1 - 0.00029 20.8 68.8 2.1 8.5 0.1 17.7 14 6 6 20 20 20 2 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM64751.1 - 0.0013 18.6 82.8 0.73 9.8 0.3 17.4 18 0 0 18 18 18 3 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM64751.1 - 0.004 17.9 86.1 1.1 10.0 2.4 10.3 5 1 5 10 10 10 4 zinc-ribbon family FYVE PF01363.21 KFM64751.1 - 0.0048 17.0 105.3 0.14 12.3 8.9 8.4 3 1 3 7 7 6 4 FYVE zinc finger BolA PF01722.18 KFM64751.1 - 0.0082 16.4 40.6 2.3 8.6 0.5 10.3 1 1 9 11 11 11 3 BolA-like protein GAGA PF09237.11 KFM64751.1 - 0.014 15.2 36.7 4.9 7.0 0.1 10.9 6 5 7 13 13 13 0 GAGA factor NAD_kinase PF01513.21 KFM64751.1 - 0.018 14.2 0.2 7.2 5.7 0.0 4.5 1 1 2 3 3 3 0 ATP-NAD kinase zf-C2H2_9 PF16293.5 KFM64751.1 - 0.022 14.6 91.9 9 6.2 0.2 18.4 6 4 13 19 19 19 0 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFM64751.1 - 0.026 14.6 89.4 14 5.9 0.1 19.3 20 0 0 20 20 20 0 Uncharacterized protein conserved in bacteria (DUF2256) IGPD PF00475.18 KFM64751.1 - 0.041 14.2 20.2 1.5 9.2 0.2 7.1 6 2 2 8 8 8 0 Imidazoleglycerol-phosphate dehydratase TAFII28 PF04719.14 KFM64751.1 - 0.064 13.4 0.8 42 4.3 0.0 4.1 4 0 0 4 4 3 0 hTAFII28-like protein conserved region Cyclase_polyket PF04673.12 KFM64751.1 - 0.085 13.1 0.2 29 5.0 0.0 3.9 2 1 1 3 3 3 0 Polyketide synthesis cyclase C1_1 PF00130.22 KFM64751.1 - 0.093 12.6 120.1 0.17 11.8 5.3 16.8 5 3 10 17 17 17 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AvrPto PF11592.8 KFM64751.1 - 0.14 12.2 2.7 6.3 6.9 0.1 4.1 4 1 1 5 5 4 0 Central core of the bacterial effector protein AvrPto ADK_lid PF05191.14 KFM64751.1 - 0.34 10.9 83.8 0.5 10.4 1.8 12.4 7 5 5 12 12 12 0 Adenylate kinase, active site lid HTH_Tnp_Tc3_2 PF01498.18 KFM64754.1 - 1.4e-12 47.6 0.2 2e-12 47.2 0.2 1.2 1 0 0 1 1 1 1 Transposase RT_RNaseH PF17917.1 KFM64755.1 - 1.4e-07 31.8 0.2 2e-07 31.2 0.2 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_1 PF03184.19 KFM64756.1 - 8.5e-42 142.8 1.3 1.2e-41 142.2 0.4 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM64756.1 - 2.8e-15 56.1 0.0 2.6e-14 53.0 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM64756.1 - 2.5e-10 39.8 0.8 7.8e-10 38.2 0.8 1.9 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 KFM64756.1 - 7.2e-05 22.8 0.1 0.0003 20.8 0.1 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM64756.1 - 0.00022 20.9 0.0 0.00075 19.2 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KFM64756.1 - 0.00023 21.1 0.0 0.0005 20.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KFM64756.1 - 0.00025 21.1 0.0 0.0015 18.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_psq PF05225.16 KFM64756.1 - 0.0011 18.7 0.0 0.0034 17.1 0.0 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.20 KFM64756.1 - 0.034 14.5 0.0 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 Transposase HTH_26 PF13443.6 KFM64756.1 - 0.057 13.9 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF3636 PF12331.8 KFM64757.1 - 0.047 13.5 0.9 0.084 12.7 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3636) zf-H2C2_2 PF13465.6 KFM64758.1 - 1.2e-78 256.3 69.9 4.9e-09 36.2 0.7 11.8 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64758.1 - 2.8e-42 140.9 85.1 5.9e-06 26.5 0.7 10.9 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64758.1 - 3.9e-35 117.5 80.9 0.0001 22.8 0.6 11.0 11 0 0 11 11 11 10 C2H2-type zinc finger zf-met PF12874.7 KFM64758.1 - 6.7e-24 83.5 68.5 0.0014 18.9 0.9 10.9 11 0 0 11 11 11 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64758.1 - 4.7e-22 77.7 41.3 0.0071 16.6 0.3 10.4 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM64758.1 - 3.4e-21 74.7 69.4 0.00046 20.1 0.4 11.3 11 0 0 11 11 11 10 C2H2-type zinc finger GAGA PF09237.11 KFM64758.1 - 1e-11 44.5 18.8 0.42 10.4 0.0 9.2 1 1 10 11 11 11 4 GAGA factor BolA PF01722.18 KFM64758.1 - 4.6e-10 39.6 6.1 0.33 11.3 0.0 6.7 1 1 4 6 6 6 2 BolA-like protein zf-C2H2_2 PF12756.7 KFM64758.1 - 5e-08 33.2 55.4 0.58 10.5 1.4 10.0 1 1 8 9 9 9 4 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM64758.1 - 1e-07 31.7 39.0 1 9.3 0.1 9.7 10 0 0 10 10 10 4 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM64758.1 - 6.7e-06 25.9 34.9 1 9.3 0.2 10.0 5 2 6 11 11 11 1 C2H2 type zinc-finger (1 copy) C1_1 PF00130.22 KFM64758.1 - 5.7e-05 22.9 49.7 3.2 7.7 0.9 9.7 1 1 9 10 10 10 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4825 PF16107.5 KFM64758.1 - 0.0015 18.6 0.0 26 5.0 0.0 4.4 2 1 3 5 5 5 0 Domain of unknown function (DUF4825) zf-CHCC PF10276.9 KFM64758.1 - 0.0018 18.3 14.9 73 3.5 0.0 8.7 10 0 0 10 10 10 0 Zinc-finger domain Tox-HNH-HHH PF15637.6 KFM64758.1 - 0.015 15.4 0.3 7.3 6.8 0.0 3.8 1 1 4 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Sec23_Sec24 PF04810.15 KFM64758.1 - 0.016 15.3 37.9 0.66 10.1 1.1 9.7 6 2 4 10 10 10 0 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM64758.1 - 0.037 14.0 34.3 5.4 7.1 3.6 6.5 2 2 3 5 5 5 0 Adenylate kinase, active site lid zf-RRPl_C4 PF17026.5 KFM64758.1 - 0.04 14.0 33.5 0.34 11.0 4.5 4.4 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFM64758.1 - 0.042 14.6 33.7 8.7 7.2 1.0 5.2 2 1 2 5 5 5 0 zinc-ribbon family DUF5511 PF17630.2 KFM64758.1 - 0.076 13.2 0.7 21 5.4 0.1 3.0 1 1 1 2 2 2 0 Family of unknown function (DUF5511) Z1 PF10593.9 KFM64758.1 - 0.088 12.3 2.3 6.5 6.2 0.1 3.4 1 1 0 3 3 3 0 Z1 domain AvrPto PF11592.8 KFM64758.1 - 0.089 12.8 0.1 18 5.4 0.1 2.7 1 1 0 2 2 2 0 Central core of the bacterial effector protein AvrPto LIM PF00412.22 KFM64758.1 - 0.11 12.7 41.9 2 8.7 2.2 7.8 4 3 3 7 7 7 0 LIM domain zf-DBF PF07535.12 KFM64758.1 - 0.15 12.2 35.2 16 5.7 0.2 8.9 10 0 0 10 10 10 0 DBF zinc finger YyzF PF14116.6 KFM64758.1 - 0.19 11.8 32.8 7.3 6.7 0.4 9.5 10 0 0 10 10 10 0 YyzF-like protein DUF2256 PF10013.9 KFM64758.1 - 0.46 10.7 39.1 11 6.2 0.1 9.7 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.10 KFM64758.1 - 0.78 9.9 32.4 2.7 8.2 1.2 6.4 3 2 3 6 6 6 0 Zinc ribbon domain zf-trcl PF13451.6 KFM64758.1 - 0.9 9.5 38.3 3.3 7.7 0.0 9.4 10 0 0 10 10 10 0 Probable zinc-ribbon domain Zf_RING PF16744.5 KFM64758.1 - 3 8.0 45.6 13 6.0 1.0 9.5 1 1 7 9 9 9 0 KIAA1045 RING finger zf-HC3 PF16827.5 KFM64758.1 - 4.4 7.6 17.7 41 4.5 0.0 8.0 10 0 0 10 10 10 0 zinc-finger Thioredoxin_16 PF18569.1 KFM64758.1 - 6.3 7.0 8.0 3.3 7.9 0.1 3.2 2 1 1 3 3 3 0 Thioredoxin-like domain TMEM141 PF15110.6 KFM64759.1 - 1.3e-26 92.9 1.1 1.5e-26 92.7 1.1 1.1 1 0 0 1 1 1 1 TMEM141 protein family Tfb2 PF03849.14 KFM64760.1 - 5.8e-134 446.5 0.1 6.7e-134 446.3 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KFM64760.1 - 6.2e-19 68.2 0.1 1.8e-18 66.7 0.1 1.8 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KFM64760.1 - 3.9e-05 23.8 0.0 0.00013 22.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SinI PF08671.10 KFM64760.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Anti-repressor SinI Phageshock_PspD PF09584.10 KFM64760.1 - 0.15 12.1 0.5 0.38 10.8 0.5 1.6 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) zf-TFIIB PF13453.6 KFM64761.1 - 0.002 17.4 0.7 0.058 12.7 0.1 2.5 2 0 0 2 2 2 1 Transcription factor zinc-finger DUF4428 PF14471.6 KFM64761.1 - 0.0075 16.2 1.6 1.9 8.5 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) zf-HIT PF04438.16 KFM64761.1 - 0.025 14.5 2.2 0.025 14.5 2.2 2.4 2 0 0 2 2 2 0 HIT zinc finger zf_UBZ PF18439.1 KFM64761.1 - 0.087 12.4 0.3 0.21 11.2 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_recom PF13408.6 KFM64761.1 - 0.11 13.0 1.0 0.11 13.0 1.0 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain DDE_Tnp_1_7 PF13843.6 KFM64762.1 - 0.0043 16.4 0.1 0.0043 16.4 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 Glyco_transf_10 PF00852.19 KFM64763.1 - 3.7e-60 202.7 6.5 5e-60 202.2 6.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFM64763.1 - 8.7e-15 55.1 0.4 1.2e-13 51.5 0.0 2.7 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal WD40 PF00400.32 KFM64764.1 - 6e-24 83.9 3.5 1.4e-05 25.7 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM64764.1 - 2e-10 40.8 0.0 0.0091 16.3 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DUF892 PF05974.12 KFM64765.1 - 0.037 14.1 0.5 0.037 14.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF892) QSregVF PF13652.6 KFM64766.1 - 0.011 15.8 0.1 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Putative quorum-sensing-regulated virulence factor AAT PF03417.16 KFM64766.1 - 0.02 14.6 1.1 0.035 13.8 1.1 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Aminopep PF10023.9 KFM64766.1 - 0.074 12.4 2.1 0.093 12.1 1.2 1.6 1 1 0 1 1 1 0 Putative aminopeptidase CRAL_TRIO PF00650.20 KFM64767.1 - 4.4e-31 107.7 0.0 7.2e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM64767.1 - 0.0025 18.0 0.0 0.0039 17.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM64767.1 - 0.0038 17.4 0.3 0.0078 16.4 0.3 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain GST_N_3 PF13417.6 KFM64768.1 - 7.3e-11 42.3 0.1 2.8e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KFM64768.1 - 6.3e-09 35.9 0.8 1.5e-08 34.8 0.8 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 KFM64768.1 - 6.9e-07 29.5 0.0 2e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KFM64768.1 - 2.9e-05 24.8 0.0 6.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 KFM64768.1 - 0.00031 21.0 0.0 0.00075 19.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.24 KFM64770.1 - 9e-11 41.3 1.9 9.1e-11 41.3 1.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM64770.1 - 0.00016 20.8 1.7 0.00016 20.7 1.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM64771.1 - 1.4e-51 175.8 9.7 1.6e-51 175.6 9.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3392 PF11872.8 KFM64771.1 - 0.021 15.0 1.8 0.047 14.0 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) COesterase PF00135.28 KFM64773.1 - 4.9e-74 250.0 0.0 7.3e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM64773.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ins_allergen_rp PF06757.13 KFM64773.1 - 0.041 13.9 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification DUF2140 PF09911.9 KFM64773.1 - 0.09 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) zf-H2C2_5 PF13909.6 KFM64775.1 - 1.1e-37 127.4 209.2 5.9e-07 29.1 1.8 26.2 27 0 0 27 27 27 17 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM64775.1 - 3.5e-12 46.0 267.0 0.014 15.8 1.2 30.8 31 0 0 31 31 31 19 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM64775.1 - 2.9e-07 30.6 246.3 0.0031 17.9 11.1 33.9 38 0 0 38 38 38 17 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM64775.1 - 4.6e-06 27.0 251.4 0.051 14.4 1.1 31.1 31 0 0 31 31 31 16 C2H2-type zinc finger zf-Di19 PF05605.12 KFM64775.1 - 0.00016 21.9 0.3 0.00016 21.9 0.3 15.9 16 1 0 16 16 16 7 Drought induced 19 protein (Di19), zinc-binding UPF0731 PF14982.6 KFM64775.1 - 0.6 10.3 3.5 6.8 6.9 0.1 3.0 3 0 0 3 3 3 0 UPF0731 family HTH_Tnp_Tc3_2 PF01498.18 KFM64776.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64776.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64776.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64776.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64776.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64777.1 - 6.3e-13 48.8 0.3 8.9e-13 48.3 0.3 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM64777.1 - 2.3e-05 24.1 1.2 8.4e-05 22.2 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 KFM64777.1 - 0.00028 21.1 0.2 0.00038 20.7 0.2 1.3 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM64777.1 - 0.00063 19.8 0.6 0.0015 18.7 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM64777.1 - 0.0012 18.8 0.2 0.0039 17.2 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.6 KFM64777.1 - 0.0014 18.3 1.0 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM64777.1 - 0.014 15.4 0.0 0.06 13.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_31 PF13560.6 KFM64777.1 - 0.041 14.2 0.5 0.041 14.2 0.5 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM64777.1 - 0.075 12.5 5.6 0.11 12.0 0.2 2.8 2 2 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 KFM64777.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 KFM64777.1 - 0.12 13.0 4.3 1.4 9.6 0.1 2.4 3 0 0 3 3 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64778.1 - 2.1e-16 59.9 2.2 3.6e-16 59.2 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64778.1 - 7e-13 48.6 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64779.1 - 1.5e-15 57.2 1.0 2.9e-15 56.3 1.0 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64779.1 - 1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64779.1 - 0.00034 21.1 6.1 0.0029 18.2 1.1 2.5 2 0 0 2 2 2 2 Homeodomain-like domain Glycos_transf_2 PF00535.26 KFM64780.1 - 7.9e-31 107.1 0.0 1.1e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KFM64780.1 - 0.00038 20.0 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.22 KFM64781.1 - 4.2e-31 107.8 0.9 6e-31 107.3 0.9 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFM64781.1 - 1e-05 25.1 0.3 1.8e-05 24.3 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 KFM64781.1 - 2.2e-05 25.1 0.0 0.007 17.1 0.2 2.7 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Kelch_6 PF13964.6 KFM64781.1 - 0.026 14.8 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 Kelch motif RVT_1 PF00078.27 KFM64783.1 - 4.4e-42 144.1 0.0 9.4e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM64783.1 - 4.8e-24 84.5 0.0 1.2e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KFM64783.1 - 2.5e-14 53.7 0.0 5.4e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 KFM64783.1 - 4.5e-08 32.9 0.0 1.9e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.6 KFM64783.1 - 0.04 13.7 0.1 0.089 12.6 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like RL PF17797.1 KFM64784.1 - 0.1 12.6 1.8 0.13 12.3 1.8 1.2 1 0 0 1 1 1 0 RL domain TPR_12 PF13424.6 KFM64787.1 - 4.4e-24 84.6 6.6 2e-11 44.0 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM64787.1 - 4.1e-17 61.2 9.0 8.6e-05 22.2 0.2 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFM64787.1 - 1.7e-16 59.5 5.8 0.085 12.8 0.0 7.3 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFM64787.1 - 1e-15 56.5 11.2 0.0033 17.4 0.1 6.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFM64787.1 - 2e-15 55.6 14.8 0.0012 18.9 0.1 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFM64787.1 - 8.9e-11 41.0 4.5 0.36 11.0 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM64787.1 - 1.8e-08 34.2 0.9 0.00034 20.1 0.1 2.4 2 0 0 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 KFM64787.1 - 4.8e-08 33.4 8.4 0.012 16.1 0.0 5.2 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM64787.1 - 5.8e-08 32.9 4.7 12 7.1 0.0 5.8 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM64787.1 - 6.1e-07 30.0 0.1 0.029 15.0 0.0 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 KFM64787.1 - 8.5e-05 22.4 2.4 0.52 10.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KFM64787.1 - 0.00013 21.9 1.7 0.075 13.1 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_11 PF13414.6 KFM64787.1 - 0.0041 16.8 4.4 0.06 13.0 0.2 4.3 4 1 0 4 4 3 1 TPR repeat ComR_TPR PF18710.1 KFM64787.1 - 0.0058 16.2 1.8 0.062 12.8 0.2 2.4 2 1 0 2 2 2 1 ComR tetratricopeptide TPR_17 PF13431.6 KFM64787.1 - 0.039 14.3 1.1 3.9 8.1 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 KFM64787.1 - 0.04 14.5 0.0 0.25 11.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) MobC PF05713.11 KFM64787.1 - 0.14 12.7 0.3 0.31 11.5 0.3 1.7 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) TPR_6 PF13174.6 KFM64787.1 - 1.1 10.0 6.5 15 6.5 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DDE_3 PF13358.6 KFM64788.1 - 1e-13 51.3 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DIL PF01843.19 KFM64788.1 - 0.08 13.2 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 DIL domain SAB PF04382.13 KFM64788.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 SAB domain Nup188 PF10487.9 KFM64789.1 - 6.7e-19 67.4 1.5 7.5e-19 67.2 1.5 1.0 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup188 PF10487.9 KFM64790.1 - 1.9e-48 165.1 0.5 2.1e-48 165.0 0.5 1.0 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Peptidase_C78 PF07910.13 KFM64790.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C78 Nup188 PF10487.9 KFM64791.1 - 5.7e-60 203.3 4.6 5.7e-60 203.3 4.6 2.3 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 HTH_Tnp_Tc3_2 PF01498.18 KFM64792.1 - 2.2e-16 59.8 2.2 4.7e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64792.1 - 1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_1 PF00001.21 KFM64793.1 - 3e-09 36.6 0.5 3.2e-09 36.5 0.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Arrestin_C PF02752.22 KFM64794.1 - 2.9e-33 115.2 0.0 3.7e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM64795.1 - 1.2e-12 47.8 0.5 2.5e-12 46.9 0.5 1.5 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM64795.1 - 9.8e-06 25.6 3.1 0.001 19.1 0.1 2.5 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.6 KFM64795.1 - 0.00012 22.6 5.5 0.00012 22.6 5.5 1.7 2 0 0 2 2 2 1 Homeodomain-like domain PAX PF00292.18 KFM64795.1 - 0.00038 20.4 0.1 0.00052 19.9 0.1 1.3 1 0 0 1 1 1 1 'Paired box' domain TrmB PF01978.19 KFM64795.1 - 0.0024 17.7 0.1 0.31 10.9 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 KFM64795.1 - 0.0027 17.6 1.7 0.016 15.1 0.1 2.3 1 1 1 2 2 2 1 MarR family HTH_23 PF13384.6 KFM64795.1 - 0.0094 15.7 6.8 0.46 10.3 0.1 3.0 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM64795.1 - 0.0095 15.9 0.7 0.75 9.9 0.1 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_33 PF13592.6 KFM64795.1 - 0.013 15.1 0.1 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Crp_2 PF13545.6 KFM64795.1 - 0.017 15.1 2.4 0.11 12.5 0.2 2.3 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain HTH_22 PF13309.6 KFM64795.1 - 0.033 14.2 0.1 0.076 13.1 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_3 PF01381.22 KFM64795.1 - 0.054 13.6 1.4 1.6 8.9 0.1 2.5 2 1 0 2 2 2 0 Helix-turn-helix HTH_26 PF13443.6 KFM64795.1 - 0.054 13.9 0.4 3.8 8.0 0.0 2.7 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 KFM64795.1 - 0.087 12.3 2.3 3 7.3 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 KFM64795.1 - 0.091 12.5 6.4 0.21 11.4 0.1 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 KFM64795.1 - 0.11 12.5 1.2 0.29 11.3 1.2 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_37 PF13744.6 KFM64795.1 - 0.16 12.0 0.0 0.61 10.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KFM64795.1 - 0.22 11.1 1.0 15 5.2 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_8 PF02954.19 KFM64795.1 - 1.2 9.0 3.2 5.7 6.8 0.1 3.0 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family DDE_3 PF13358.6 KFM64796.1 - 5e-05 23.1 0.0 5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PH PF00169.29 KFM64797.1 - 2.8e-08 34.2 0.1 4.4e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM64797.1 - 0.0022 18.4 3.0 0.013 16.0 3.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain HECT PF00632.25 KFM64798.1 - 7.5e-83 278.5 0.1 1.5e-82 277.5 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WWE PF02825.20 KFM64798.1 - 9.7e-21 74.1 0.2 2.1e-20 73.1 0.2 1.6 1 0 0 1 1 1 1 WWE domain HEAT_EZ PF13513.6 KFM64798.1 - 0.0078 16.7 1.0 23 5.6 0.3 4.6 5 0 0 5 5 5 2 HEAT-like repeat Gas_vesicle_C PF01304.17 KFM64798.1 - 0.056 13.5 1.2 0.17 11.9 1.2 1.8 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Spore_III_AB PF09548.10 KFM64799.1 - 0.00065 19.9 0.7 0.0016 18.6 0.7 1.6 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Apolipoprotein PF01442.18 KFM64799.1 - 0.012 15.4 5.8 0.035 14.0 3.4 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.13 KFM64799.1 - 0.025 14.1 2.3 0.14 11.7 1.6 2.4 2 0 0 2 2 2 0 fzo-like conserved region Zw10 PF06248.13 KFM64799.1 - 0.096 11.2 2.3 0.15 10.6 2.3 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 COG2 PF06148.11 KFM64799.1 - 0.11 12.5 5.9 0.15 12.2 3.7 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1640 PF07798.11 KFM64799.1 - 0.12 12.4 10.9 0.56 10.2 2.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) Phasin PF05597.11 KFM64799.1 - 0.19 11.7 5.5 0.16 12.0 3.5 1.8 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF148 PF02520.17 KFM64799.1 - 0.22 11.6 4.7 2.3 8.4 4.6 2.3 1 1 0 1 1 1 0 Domain of unknown function DUF148 Syntaxin-6_N PF09177.11 KFM64799.1 - 0.42 11.2 3.5 1 9.9 2.3 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Spectrin PF00435.21 KFM64799.1 - 0.64 10.5 5.0 5 7.7 4.0 2.7 2 1 1 3 3 3 0 Spectrin repeat WXG100 PF06013.12 KFM64799.1 - 0.7 10.2 4.9 1.4 9.2 2.9 2.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF4854 PF16146.5 KFM64799.1 - 0.74 10.2 4.5 1.4 9.3 1.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4854) MbeB_N PF04837.12 KFM64799.1 - 0.76 10.1 4.5 1.4 9.2 2.7 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region TMPIT PF07851.13 KFM64799.1 - 2 7.6 5.5 1.7 7.8 4.0 1.6 1 1 0 1 1 1 0 TMPIT-like protein DUF883 PF05957.13 KFM64799.1 - 2.4 8.8 4.7 9.8 6.9 1.2 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PRE_C2HC PF07530.11 KFM64800.1 - 3e-09 36.8 0.0 5.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Associated with zinc fingers zinc_ribbon_15 PF17032.5 KFM64800.1 - 0.012 16.3 0.1 0.029 15.1 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon family YozE_SAM_like PF06855.12 KFM64800.1 - 0.11 12.7 0.1 0.52 10.5 0.1 2.2 2 0 0 2 2 2 0 YozE SAM-like fold zf-CCHC PF00098.23 KFM64800.1 - 0.22 11.7 4.4 0.49 10.6 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle Transposase_1 PF01359.18 KFM64801.1 - 8.7e-24 83.2 0.7 1.7e-23 82.2 0.7 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) RVT_1 PF00078.27 KFM64801.1 - 1.5e-06 27.9 0.1 4.7e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 KFM64801.1 - 2.8e-05 23.9 0.0 5.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_48 PF17906.1 KFM64801.1 - 0.00051 20.1 0.4 0.0054 16.8 0.0 2.5 1 1 1 2 2 2 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM64801.1 - 0.00054 20.5 0.0 0.0022 18.5 0.0 2.2 1 1 0 1 1 1 1 Homeodomain-like domain RVT_1 PF00078.27 KFM64802.1 - 5e-22 78.5 1.0 1.1e-21 77.4 1.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KFM64802.1 - 1.5e-08 35.0 6.8 3.8e-08 33.6 4.3 2.6 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 KFM64802.1 - 1.9e-06 27.7 0.2 4.6e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like HTH_Tnp_Tc3_2 PF01498.18 KFM64803.1 - 2.5e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64803.1 - 8.7e-14 51.5 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Ig_3 PF13927.6 KFM64804.1 - 4.5e-12 46.4 0.0 6.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM64804.1 - 3.7e-11 43.0 0.0 9.5e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM64804.1 - 1e-09 38.6 0.0 0.00042 20.6 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM64804.1 - 5.1e-09 36.1 0.0 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFM64804.1 - 0.0001 22.4 0.1 0.00079 19.6 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFM64804.1 - 0.0027 17.7 0.0 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFM64804.1 - 0.006 16.6 0.0 0.079 13.0 0.0 2.5 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM64804.1 - 0.063 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Iso_dh PF00180.20 KFM64805.1 - 3.8e-77 259.8 0.0 4.5e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase V-SNARE_C PF12352.8 KFM64806.1 - 8.5e-20 70.8 2.9 8.5e-20 70.8 2.9 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFM64806.1 - 0.00038 20.3 0.7 0.00085 19.2 0.1 1.8 2 0 0 2 2 2 1 Sec20 Syntaxin_2 PF14523.6 KFM64806.1 - 0.006 16.9 0.6 0.006 16.9 0.6 2.0 1 1 1 2 2 2 1 Syntaxin-like protein NDUF_C2 PF06374.11 KFM64806.1 - 0.041 14.0 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) HTH_Tnp_Tc3_2 PF01498.18 KFM64809.1 - 6.2e-17 61.6 3.8 1.4e-16 60.5 3.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64809.1 - 3.7e-12 46.2 0.0 7.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64809.1 - 1.4e-05 25.6 2.5 1.4e-05 25.6 2.5 2.6 3 0 0 3 3 3 1 Homeodomain-like domain DUF2642 PF10842.8 KFM64809.1 - 0.16 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Roc PF08477.13 KFM64810.1 - 0.25 11.6 0.1 0.37 11.0 0.1 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AdoMet_dc PF02675.15 KFM64811.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase Y_phosphatase PF00102.27 KFM64812.1 - 1.3e-07 31.4 0.2 2.2e-07 30.7 0.1 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 KFM64813.1 - 6.4e-26 91.4 0.0 7.4e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM64813.1 - 0.00018 21.3 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM64813.1 - 0.00064 19.8 0.0 0.00068 19.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM64813.1 - 0.062 13.4 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate YhhN PF07947.14 KFM64814.1 - 2.2e-15 56.7 2.3 2.7e-15 56.5 2.3 1.1 1 0 0 1 1 1 1 YhhN family DDE_3 PF13358.6 KFM64816.1 - 1.5e-10 41.0 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64818.1 - 2.2e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64818.1 - 8.8e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM64819.1 - 2.7e-16 59.6 0.1 3.1e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64819.1 - 1.5e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Pkinase PF00069.25 KFM64822.1 - 9.9e-45 152.9 0.3 1.1e-44 152.8 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM64822.1 - 2.6e-25 89.2 0.1 2.9e-25 89.0 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM64822.1 - 0.00011 22.2 0.0 0.0003 20.8 0.0 1.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFM64822.1 - 0.0023 17.6 0.0 0.0029 17.2 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KFM64822.1 - 0.04 12.8 0.1 0.16 10.9 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFM64822.1 - 0.17 11.2 0.1 0.39 10.0 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2 PF00096.26 KFM64823.1 - 1.9e-07 31.1 2.9 1.9e-07 31.1 2.9 2.5 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM64823.1 - 1.9e-05 24.9 0.6 1.9e-05 24.9 0.6 3.0 3 1 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KFM64823.1 - 0.00012 22.4 1.1 0.00012 22.4 1.1 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64823.1 - 0.0003 21.0 0.3 0.0003 21.0 0.3 2.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFM64823.1 - 0.00036 21.1 2.6 0.00036 21.1 2.6 2.3 2 1 0 2 2 2 1 C2H2-type zinc finger zf-MYST PF17772.1 KFM64823.1 - 0.096 12.3 7.6 0.84 9.3 1.8 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain zf-H2C2_5 PF13909.6 KFM64823.1 - 0.98 9.2 10.4 0.5 10.2 6.2 2.4 2 2 0 2 2 2 0 C2H2-type zinc-finger domain Chitin_bind_4 PF00379.23 KFM64824.1 - 7.8e-07 29.5 1.5 1.1e-06 29.1 1.5 1.2 1 0 0 1 1 1 1 Insect cuticle protein DHHC PF01529.20 KFM64826.1 - 6.3e-31 107.3 13.4 6.3e-31 107.3 13.4 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase SH3_9 PF14604.6 KFM64826.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.17 KFM64826.1 - 0.013 15.1 0.1 0.046 13.4 0.1 1.9 1 0 0 1 1 1 0 Variant SH3 domain Linker_histone PF00538.19 KFM64827.1 - 3.4e-28 97.8 1.2 3.4e-28 97.8 1.2 2.1 2 1 0 2 2 2 1 linker histone H1 and H5 family RasGAP PF00616.19 KFM64827.1 - 0.41 10.3 0.0 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase DAG_kinase_N PF14513.6 KFM64827.1 - 8.2 6.6 7.4 11 6.2 5.8 2.0 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus PX PF00787.24 KFM64828.1 - 8e-10 38.7 0.9 1.3e-09 38.1 0.9 1.3 1 0 0 1 1 1 1 PX domain ICMT PF04140.14 KFM64833.1 - 5.4e-29 100.5 0.6 8.3e-29 99.9 0.6 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KFM64833.1 - 4.3e-08 33.5 0.9 6.9e-08 32.8 0.9 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KFM64833.1 - 0.0016 18.0 2.4 0.002 17.7 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) YhhN PF07947.14 KFM64833.1 - 0.025 14.2 1.2 0.038 13.6 1.2 1.3 1 0 0 1 1 1 0 YhhN family PLDc PF00614.22 KFM64835.1 - 8.5e-09 35.2 0.2 2.6e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Phospholipase D Active site motif DUF148 PF02520.17 KFM64835.1 - 5.7 7.1 7.1 0.18 11.9 0.3 2.0 3 0 0 3 3 3 0 Domain of unknown function DUF148 ATP-synt_D PF01813.17 KFM64837.1 - 1.2e-05 25.2 1.3 4.7e-05 23.3 1.3 1.8 1 1 0 1 1 1 1 ATP synthase subunit D DKNYY PF13644.6 KFM64837.1 - 0.013 16.3 0.0 0.024 15.4 0.0 1.5 1 1 0 1 1 1 0 DKNYY family Peptidase_S41_N PF11918.8 KFM64837.1 - 0.084 13.1 1.8 2.9 8.1 0.3 2.4 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Chitin_bind_4 PF00379.23 KFM64839.1 - 2.6e-10 40.7 7.0 4e-10 40.1 7.0 1.3 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM64840.1 - 4.2e-10 40.0 4.3 6.3e-10 39.4 4.3 1.3 1 0 0 1 1 1 1 Insect cuticle protein Herpes_UL4 PF03277.13 KFM64840.1 - 0.73 9.4 3.1 34 4.0 2.0 2.8 2 1 0 2 2 2 0 Herpesvirus UL4 family RT_RNaseH_2 PF17919.1 KFM64842.1 - 1.1e-30 105.6 0.0 5.2e-30 103.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM64842.1 - 3.1e-29 101.3 0.0 1.5e-28 99.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM64842.1 - 2.3e-28 99.2 0.1 6e-28 97.9 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM64842.1 - 2.2e-18 66.6 0.0 3.9e-17 62.6 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM64842.1 - 2.3e-16 59.6 0.0 8.2e-16 57.9 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Arc_C PF18162.1 KFM64842.1 - 4.2e-05 23.3 1.7 0.00014 21.6 0.4 2.6 3 0 0 3 3 3 1 Arc C-lobe zf-H2C2 PF09337.10 KFM64842.1 - 0.0016 18.6 0.0 0.0043 17.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM64842.1 - 0.027 14.8 2.9 0.25 11.7 0.0 3.7 3 0 0 3 3 3 0 Retrotransposon gag protein DDE_3 PF13358.6 KFM64843.1 - 2.7e-10 40.2 0.0 3.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64844.1 - 2.6e-16 59.6 2.2 4.8e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64844.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Chitin_bind_4 PF00379.23 KFM64845.1 - 1.4e-10 41.6 3.8 2.2e-10 40.9 3.8 1.4 1 0 0 1 1 1 1 Insect cuticle protein RT_RNaseH_2 PF17919.1 KFM64846.1 - 9.9e-31 105.8 0.0 4.6e-30 103.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM64846.1 - 2.4e-29 101.7 0.2 1.3e-28 99.4 0.0 2.4 3 0 0 3 3 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KFM64846.1 - 1.8e-18 66.8 0.0 3.4e-17 62.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM64846.1 - 1.9e-16 59.9 0.0 7.3e-16 58.0 0.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain Apolipoprotein PF01442.18 KFM64846.1 - 5.3e-08 33.0 17.3 1.4e-07 31.6 13.9 2.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM64846.1 - 3.6e-05 23.8 1.5 0.0017 18.4 0.8 2.6 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus zf-H2C2 PF09337.10 KFM64846.1 - 0.0014 18.8 0.0 0.0038 17.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger HSBP1 PF06825.12 KFM64846.1 - 0.0064 16.3 1.5 3.3 7.6 0.1 3.3 3 0 0 3 3 3 1 Heat shock factor binding protein 1 MnmE_helical PF12631.7 KFM64846.1 - 0.04 14.1 5.3 1 9.5 2.4 3.0 2 1 0 2 2 2 0 MnmE helical domain Tweety PF04906.13 KFM64846.1 - 0.13 10.9 1.9 0.25 10.0 1.9 1.5 1 0 0 1 1 1 0 Tweety CdvA PF18822.1 KFM64846.1 - 0.23 11.3 20.3 0.69 9.7 1.2 4.5 1 1 1 3 3 3 0 CdvA-like coiled-coil domain Tnp_22_trimer PF17489.2 KFM64846.1 - 0.24 11.4 12.8 1.5 8.9 0.7 5.3 2 1 2 4 4 4 0 L1 transposable element trimerization domain DUF1640 PF07798.11 KFM64846.1 - 1.2 9.2 28.8 0.076 13.1 16.9 3.4 3 1 1 4 4 3 0 Protein of unknown function (DUF1640) DUF1664 PF07889.12 KFM64846.1 - 1.7 8.7 26.4 0.03 14.3 8.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CLZ PF16526.5 KFM64846.1 - 3.7 8.0 10.4 2.2 8.7 2.3 3.8 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoO PF09769.9 KFM64846.1 - 4.9 7.1 17.1 5.9 6.9 3.9 5.1 4 1 2 6 6 5 0 Apolipoprotein O Fzo_mitofusin PF04799.13 KFM64846.1 - 8.2 6.0 15.7 0.85 9.2 5.0 2.9 1 1 1 2 2 2 0 fzo-like conserved region ApoLp-III PF07464.11 KFM64846.1 - 9.9 6.2 25.8 12 6.0 22.5 2.9 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Chitin_bind_4 PF00379.23 KFM64847.1 - 1.1e-09 38.6 5.2 2e-09 37.8 5.2 1.4 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM64848.1 - 2.8e-10 40.6 2.5 4.4e-10 39.9 2.5 1.3 1 0 0 1 1 1 1 Insect cuticle protein zf-CCCH_4 PF18044.1 KFM64849.1 - 2.9e-11 42.9 3.3 5.9e-11 41.9 3.3 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KFM64849.1 - 7.9e-08 32.0 1.4 1.5e-07 31.2 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM64849.1 - 1.1e-07 31.6 4.8 2.1e-07 30.7 4.8 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 KFM64849.1 - 0.002 18.5 2.0 0.0039 17.6 2.0 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KFM64849.1 - 0.046 14.4 0.9 0.046 14.4 0.9 3.0 2 2 1 3 3 3 0 Torus domain ER_lumen_recept PF00810.18 KFM64850.1 - 3.8e-56 190.0 9.6 3.8e-56 190.0 9.6 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KFM64850.1 - 0.87 9.4 12.4 2.1 8.2 0.3 3.7 3 1 0 3 3 3 0 PQ loop repeat XRN_N PF03159.18 KFM64851.1 - 3.6e-92 308.2 0.0 4.1e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KFM64852.1 - 4e-173 576.4 0.0 5.4e-173 576.0 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain Homeodomain PF00046.29 KFM64853.1 - 1.2e-20 73.1 4.4 1.9e-20 72.5 4.4 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM64853.1 - 0.028 14.3 0.2 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Homeobox KN domain CDK2AP PF09806.9 KFM64853.1 - 1 9.4 8.0 0.13 12.3 3.5 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DDE_3 PF13358.6 KFM64854.1 - 5.8e-16 58.6 0.1 6.4e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64854.1 - 7.7e-16 58.1 6.5 1.5e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM64854.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM64854.1 - 0.0029 17.4 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64854.1 - 0.017 15.3 0.1 0.068 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM64854.1 - 0.037 14.1 0.4 0.037 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix Glyco_hydro_31 PF01055.26 KFM64855.1 - 3.9e-75 253.7 0.4 4.7e-75 253.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFM64855.1 - 2.1e-07 31.1 0.2 6.1e-07 29.7 0.2 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like LRR_8 PF13855.6 KFM64856.1 - 1e-68 227.0 71.0 3.5e-14 52.3 0.1 7.0 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFM64856.1 - 2.2e-31 107.4 47.2 5.2e-05 23.5 0.0 9.3 7 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM64856.1 - 9.8e-26 90.2 10.4 2.8e-11 43.5 0.5 3.7 3 0 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM64856.1 - 9.1e-24 83.9 21.5 3.1e-08 33.3 1.8 5.0 3 2 2 5 5 5 5 Leucine-rich repeat LRRNT PF01462.18 KFM64856.1 - 4e-10 39.1 18.6 1.1e-06 28.2 4.9 4.0 5 0 0 5 5 5 2 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFM64856.1 - 2.6e-06 27.2 37.6 7.7 7.5 0.0 13.2 12 3 2 14 14 14 2 Leucine Rich Repeat LRRCT PF01463.24 KFM64856.1 - 0.00074 19.9 0.9 3.8 8.3 0.0 4.4 4 0 0 4 4 4 2 Leucine rich repeat C-terminal domain TPKR_C2 PF16920.5 KFM64856.1 - 0.0019 18.3 16.4 0.0072 16.4 0.5 5.7 5 0 0 5 5 5 1 Tyrosine-protein kinase receptor C2 Ig-like domain VraX PF17412.2 KFM64856.1 - 0.0039 16.8 1.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 2 Family of unknown function Beta_helix PF13229.6 KFM64856.1 - 0.2 11.5 3.6 5.7 6.8 0.2 3.1 3 0 0 3 3 3 0 Right handed beta helix region Gastrin PF00918.17 KFM64857.1 - 0.014 16.3 1.5 0.015 16.3 1.5 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF3088 PF11287.8 KFM64857.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) GATA PF00320.27 KFM64857.1 - 4.4 7.0 7.2 8.3 6.1 0.1 2.8 2 1 1 3 3 3 0 GATA zinc finger Pro_isomerase PF00160.21 KFM64859.1 - 8.3e-48 162.6 0.3 9.9e-48 162.4 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RAMP4 PF06624.12 KFM64860.1 - 0.04 14.0 0.4 0.068 13.2 0.4 1.3 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 NS3_envE PF02723.14 KFM64860.1 - 0.058 13.5 0.1 0.073 13.2 0.1 1.3 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Exostosin PF03016.15 KFM64861.1 - 0.002 17.4 0.0 0.002 17.4 0.0 1.0 1 0 0 1 1 1 1 Exostosin family Glyco_transf_64 PF09258.10 KFM64862.1 - 1.7e-98 328.8 0.6 2.4e-98 328.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KFM64862.1 - 1.5e-22 80.2 0.1 2.2e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Exostosin family Piwi PF02171.17 KFM64863.1 - 4.5e-82 275.7 0.0 8.6e-82 274.8 0.0 1.5 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KFM64863.1 - 3.5e-34 117.6 0.5 6.7e-34 116.6 0.5 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KFM64863.1 - 6e-06 26.9 0.0 1.8e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFM64863.1 - 0.00074 19.1 0.0 0.0031 17.1 0.0 2.2 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KFM64863.1 - 0.0078 16.4 0.0 0.037 14.3 0.0 2.2 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 KFM64863.1 - 0.1 12.9 0.0 0.48 10.8 0.0 2.2 1 0 0 1 1 1 0 Argonaute linker 2 domain SRP14 PF02290.15 KFM64863.1 - 0.12 12.8 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 Signal recognition particle 14kD protein SBDS PF01172.18 KFM64865.1 - 1.7e-11 44.0 0.1 3.5e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein 2-Hacid_dh_C PF02826.19 KFM64865.1 - 0.15 11.4 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SBDS_C PF09377.10 KFM64866.1 - 5.9e-16 58.5 0.5 8.3e-16 58.0 0.5 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM64867.1 - 2.5e-16 59.7 2.2 6.8e-16 58.3 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64867.1 - 1.6e-13 50.6 0.0 2.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64867.1 - 3.6e-07 29.8 1.6 8.2e-07 28.7 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64867.1 - 0.0033 17.2 0.5 0.0088 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64867.1 - 0.035 14.3 0.4 0.11 12.7 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain SBDS_C PF09377.10 KFM64867.1 - 0.13 12.3 0.0 11 6.1 0.0 2.3 1 1 1 2 2 2 0 SBDS protein C-terminal domain HTH_32 PF13565.6 KFM64867.1 - 3.6 8.3 15.6 0.15 12.7 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Clathrin PF00637.20 KFM64868.1 - 1.2e-208 683.4 45.3 4.6e-34 117.3 2.1 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KFM64868.1 - 6.2e-47 155.7 4.6 3.9e-07 30.1 0.0 6.5 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KFM64868.1 - 1.3e-32 111.5 0.9 5.3e-32 109.5 0.9 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 KFM64868.1 - 1.2e-11 43.7 0.5 3.5e-11 42.3 0.5 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KFM64868.1 - 8.4e-07 28.4 4.1 0.001 18.2 0.1 3.8 3 0 0 3 3 3 2 Coatomer WD associated region TPR_7 PF13176.6 KFM64868.1 - 1.2e-05 25.0 3.9 0.52 10.5 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM64868.1 - 0.00026 21.1 1.0 0.16 12.2 0.1 4.9 5 0 0 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KFM64868.1 - 0.0019 18.8 8.2 7.1 7.7 0.2 7.4 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM64868.1 - 0.0096 16.4 4.7 0.52 10.8 0.2 5.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM64868.1 - 0.032 14.3 9.5 0.92 9.8 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM64868.1 - 0.063 13.1 0.0 0.063 13.1 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Alpha-amylase_C PF02806.18 KFM64868.1 - 0.11 13.0 0.0 3.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain LVIVD PF08309.11 KFM64868.1 - 0.11 11.8 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 LVIVD repeat Ribosomal_60s PF00428.19 KFM64869.1 - 7.4e-17 61.7 7.5 8.5e-17 61.5 7.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PTPS PF01242.19 KFM64870.1 - 1.1e-36 125.5 0.2 1.2e-36 125.3 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DDE_3 PF13358.6 KFM64871.1 - 5.9e-11 42.3 0.0 8.7e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64871.1 - 2.5e-06 27.6 0.2 5.1e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM64872.1 - 1.4e-13 50.8 3.6 3.3e-13 49.7 3.6 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64872.1 - 7.4e-09 35.5 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.6 KFM64872.1 - 0.0019 17.6 0.3 0.18 11.3 0.0 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KFM64872.1 - 0.0043 17.2 0.5 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.7 KFM64872.1 - 0.022 14.8 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM64872.1 - 0.041 13.9 0.4 0.21 11.6 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 KFM64872.1 - 0.073 12.9 1.1 0.82 9.5 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.6 KFM64872.1 - 1.6 9.4 7.7 2.3 8.9 0.6 2.6 1 1 1 2 2 2 0 Homeodomain-like domain DREV PF05219.12 KFM64873.1 - 2.8e-55 187.3 0.0 3.1e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 KFM64873.1 - 5.2e-16 58.9 0.0 6.1e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM64873.1 - 8.5e-08 32.9 0.0 1.4e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM64873.1 - 3.6e-07 30.7 0.0 5.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM64873.1 - 3e-05 23.9 0.1 0.00032 20.5 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM64873.1 - 4.9e-05 24.0 0.0 8.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KFM64873.1 - 0.04 13.0 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.11 KFM64873.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Mto2_bdg PF12808.7 KFM64874.1 - 0.033 14.5 0.5 0.033 14.5 0.5 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Atg14 PF10186.9 KFM64874.1 - 0.19 10.8 2.7 0.27 10.3 2.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HTH_Tnp_Tc3_2 PF01498.18 KFM64876.1 - 3.7e-16 59.1 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64876.1 - 1.4e-13 50.8 0.0 2.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64876.1 - 3e-07 30.1 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64876.1 - 0.0025 17.6 0.6 0.0082 15.9 0.6 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64876.1 - 0.031 14.4 0.4 0.098 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM64876.1 - 2.5 8.8 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain zf-C2H2 PF00096.26 KFM64877.1 - 6.6e-23 79.8 45.9 0.00022 21.5 0.9 7.2 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64877.1 - 7e-22 76.2 45.9 0.0011 19.6 0.6 7.3 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM64877.1 - 3.7e-10 39.8 46.9 0.004 17.5 2.1 7.8 8 0 0 8 8 7 5 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KFM64877.1 - 1.8e-08 35.1 16.5 0.0004 21.1 1.0 4.4 2 1 3 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KFM64877.1 - 2e-08 34.3 36.2 0.04 14.2 2.0 6.9 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM64877.1 - 1.4e-05 25.3 31.1 0.026 14.9 0.4 6.2 1 1 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFM64877.1 - 4.8e-05 23.2 49.0 0.71 9.9 1.9 7.9 7 2 0 7 7 7 4 C2H2-type zinc finger zf-TRAF PF02176.18 KFM64877.1 - 0.0028 18.3 6.3 0.013 16.2 4.1 4.8 6 0 0 6 6 5 2 TRAF-type zinc finger zf-C2H2_11 PF16622.5 KFM64877.1 - 0.01 15.6 21.5 0.25 11.1 0.0 6.8 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-met PF12874.7 KFM64877.1 - 0.05 14.0 3.1 0.05 14.0 3.1 6.9 7 0 0 7 7 7 0 Zinc-finger of C2H2 type FAM86 PF14904.6 KFM64877.1 - 0.086 12.9 0.1 0.27 11.4 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function zf-Di19 PF05605.12 KFM64877.1 - 0.11 12.8 31.2 1.5 9.2 7.2 5.2 3 2 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-LYAR PF08790.11 KFM64877.1 - 0.12 12.3 14.5 1.6 8.7 0.1 5.5 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger HalOD2 PF18547.1 KFM64877.1 - 0.16 11.9 4.7 4.8 7.2 0.0 3.9 4 0 0 4 4 4 0 Halobacterial output domain 2 zf_UBZ PF18439.1 KFM64877.1 - 0.42 10.3 0.1 0.42 10.3 0.1 6.4 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM64877.1 - 0.56 10.2 0.1 0.56 10.2 0.1 5.0 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 KFM64877.1 - 0.84 8.8 17.4 1 8.5 6.8 3.3 1 1 1 3 3 3 0 Putative actin-like family zf-C2H2_9 PF16293.5 KFM64877.1 - 0.84 9.5 0.1 0.84 9.5 0.1 4.9 5 1 2 7 7 6 0 C2H2 type zinc-finger (1 copy) C1_4 PF07975.12 KFM64877.1 - 0.92 9.8 27.6 1.7 8.9 0.2 5.8 4 2 3 7 7 7 0 TFIIH C1-like domain zf-ribbon_3 PF13248.6 KFM64877.1 - 1.8 8.1 7.4 1 8.8 0.1 3.2 3 0 0 3 3 2 0 zinc-ribbon domain zf-C2HE PF16278.5 KFM64877.1 - 3.8 8.0 35.6 1.9 9.0 2.9 6.2 4 3 2 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 KFM64877.1 - 4.7 7.3 16.5 0.48 10.4 2.4 3.5 2 2 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_11 PF16622.5 KFM64878.1 - 9.9e-06 25.2 0.8 0.00031 20.4 0.1 4.4 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFM64878.1 - 0.00024 21.7 2.2 0.013 16.3 0.2 5.4 4 1 2 6 6 6 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM64878.1 - 0.013 15.9 0.6 0.013 15.9 0.6 5.0 5 0 0 5 5 5 0 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.12 KFM64878.1 - 0.015 14.8 2.9 0.015 14.8 2.9 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding zf-H2C2_2 PF13465.6 KFM64878.1 - 0.027 14.9 0.7 0.027 14.9 0.7 4.6 4 2 0 4 4 3 0 Zinc-finger double domain zf-LYAR PF08790.11 KFM64878.1 - 0.029 14.3 1.6 0.029 14.3 1.6 4.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger RNA_POL_M_15KD PF02150.16 KFM64878.1 - 0.034 14.0 5.8 5.7 6.9 0.1 3.6 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit DNA_RNApol_7kD PF03604.13 KFM64878.1 - 0.066 12.9 1.3 0.066 12.9 1.3 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_6 PF13912.6 KFM64878.1 - 0.13 12.3 0.3 0.13 12.3 0.3 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.11 KFM64878.1 - 0.16 11.9 6.9 1.2 9.1 2.4 2.6 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf_C2H2_ZHX PF18387.1 KFM64878.1 - 0.43 10.3 8.0 1.3 8.7 0.1 3.1 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 KFM64878.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.5 2 1 1 3 3 2 0 C2H2 type zinc-finger (1 copy) Cytochrom_CIII PF02085.16 KFM64878.1 - 4.2 7.8 22.6 51 4.3 22.6 2.2 1 1 0 1 1 1 0 Class III cytochrome C family DUF2197 PF09963.9 KFM64878.1 - 6.5 7.1 11.5 8.5 6.7 5.0 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2H2_4 PF13894.6 KFM64879.1 - 1.8e-23 81.2 63.3 0.015 16.1 1.3 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM64879.1 - 2.6e-19 68.5 59.3 0.0041 17.5 1.2 10.7 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM64879.1 - 1.1e-10 41.5 59.7 0.0048 17.2 0.1 10.7 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM64879.1 - 9.3e-08 32.2 57.2 0.0018 18.6 0.1 10.1 11 0 0 11 11 11 6 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM64879.1 - 2.4e-06 27.7 51.3 0.0034 17.6 2.0 6.8 6 1 1 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFM64879.1 - 0.00029 20.8 62.6 0.0087 16.0 0.5 9.9 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFM64879.1 - 0.0021 18.7 36.4 0.025 15.3 0.8 5.4 3 1 1 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 KFM64879.1 - 0.1 13.1 0.0 0.1 13.1 0.0 7.5 5 2 1 6 6 5 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 KFM64879.1 - 0.23 11.4 26.0 2.8 7.9 0.2 7.7 8 1 0 8 8 8 0 SprT-like zinc ribbon domain Vps36-NZF-N PF16988.5 KFM64879.1 - 0.24 10.8 0.0 0.24 10.8 0.0 3.7 4 0 0 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_2 PF12756.7 KFM64879.1 - 1.1 9.6 56.3 0.93 9.9 2.9 9.3 3 2 6 9 9 9 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM64880.1 - 3.1e-07 30.6 5.1 0.0015 19.2 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM64880.1 - 3.9e-07 30.1 5.2 0.069 13.6 0.0 3.7 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-Di19 PF05605.12 KFM64880.1 - 0.0025 18.1 1.8 0.58 10.5 0.1 2.5 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFM64880.1 - 0.0027 17.4 0.1 0.0027 17.4 0.1 3.8 4 1 0 4 4 4 1 zinc-finger C2H2-type zf-met PF12874.7 KFM64880.1 - 0.028 14.8 0.1 0.028 14.8 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KFM64880.1 - 0.04 13.6 1.3 7.8 6.2 0.0 2.7 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KFM64880.1 - 0.05 13.9 3.0 0.053 13.8 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KFM64880.1 - 0.07 13.8 1.8 1.7 9.3 0.2 2.2 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KFM64880.1 - 0.093 13.1 1.1 16 5.9 0.0 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFM64880.1 - 0.86 10.1 3.6 3.7 8.1 0.2 2.4 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DDE_3 PF13358.6 KFM64882.1 - 2.8e-06 27.2 0.0 5.5e-06 26.2 0.0 1.5 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64883.1 - 6.7e-09 35.9 0.1 9.9e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Transposase TRAPPC9-Trs120 PF08626.11 KFM64885.1 - 6.1e-38 129.9 0.1 1.3e-19 69.3 1.0 3.1 1 1 1 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC-Trs85 PF12739.7 KFM64885.1 - 0.031 13.2 2.8 0.068 12.1 2.6 1.7 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_12 PF13424.6 KFM64885.1 - 0.11 12.7 2.4 4.7 7.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TRAPPC9-Trs120 PF08626.11 KFM64886.1 - 3.8e-08 31.2 0.1 0.00056 17.4 0.0 2.6 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit zf-RING_9 PF13901.6 KFM64886.1 - 0.043 13.8 0.3 0.043 13.8 0.3 1.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DUF563 PF04577.14 KFM64888.1 - 2.4e-22 80.1 0.0 2.6e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF563) USP7_C2 PF14533.6 KFM64888.1 - 0.0056 16.4 0.0 0.0065 16.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal Arabinose_Iso_C PF11762.8 KFM64888.1 - 0.01 15.7 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain PMBR PF09373.10 KFM64889.1 - 0.13 12.5 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Pseudomurein-binding repeat AdoHcyase PF05221.17 KFM64892.1 - 5.1e-118 393.6 0.0 1.1e-64 218.5 0.3 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KFM64892.1 - 5.4e-76 254.1 3.4 8.2e-76 253.6 3.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM64892.1 - 1.4e-08 34.3 0.1 2.5e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFM64892.1 - 5.8e-05 22.7 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 KFM64892.1 - 0.00029 20.2 1.4 0.0011 18.3 1.4 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KFM64892.1 - 0.00035 21.0 1.4 0.0033 17.8 0.5 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KFM64892.1 - 0.0036 17.4 0.2 0.011 15.9 0.2 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KFM64892.1 - 0.0064 15.8 1.1 0.024 13.9 1.1 1.9 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KFM64892.1 - 0.064 13.5 0.2 0.17 12.2 0.1 1.8 1 1 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.21 KFM64892.1 - 0.11 12.2 0.9 1 9.0 0.5 2.0 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GAS PF13851.6 KFM64893.1 - 1.3e-05 24.7 34.4 0.00012 21.5 17.3 2.5 1 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KFM64893.1 - 0.016 15.7 37.3 0.2 12.1 17.0 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF4164 PF13747.6 KFM64893.1 - 0.017 15.4 1.8 0.017 15.4 1.8 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 KFM64893.1 - 0.024 14.7 8.0 0.025 14.6 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.13 KFM64893.1 - 0.06 13.2 15.0 0.064 13.1 3.9 3.0 1 1 1 3 3 3 0 Nsp1-like C-terminal region CENP-F_leu_zip PF10473.9 KFM64893.1 - 0.063 13.3 32.9 0.071 13.1 18.5 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHE3 PF17078.5 KFM64893.1 - 0.082 12.6 23.1 0.36 10.5 22.9 1.9 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 KFM64893.1 - 0.16 10.8 26.3 0.0092 14.9 17.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 KFM64893.1 - 0.38 8.2 19.9 0.017 12.7 13.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 KFM64893.1 - 0.45 9.8 7.5 0.66 9.3 7.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KFM64893.1 - 0.78 9.9 13.1 0.17 12.0 9.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2524 PF10732.9 KFM64893.1 - 0.86 9.9 7.6 0.27 11.6 3.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) T3SSipB PF16535.5 KFM64893.1 - 0.97 9.9 9.1 0.73 10.3 5.4 2.0 2 0 0 2 2 2 0 Type III cell invasion protein SipB BRE1 PF08647.11 KFM64893.1 - 3.3 7.8 32.8 0.26 11.4 12.5 3.4 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase Rootletin PF15035.6 KFM64893.1 - 3.7 7.5 20.6 1.5e+02 2.3 20.6 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HAUS-augmin3 PF14932.6 KFM64893.1 - 4.5 6.8 24.6 1.8 8.0 11.1 2.4 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Atg14 PF10186.9 KFM64893.1 - 5.4 6.0 14.7 9.5 5.2 14.7 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_CLD_2 PF14197.6 KFM64893.1 - 7.8 6.7 19.1 0.2 11.7 3.9 3.6 2 2 0 3 3 3 0 Centrosome localisation domain of PPC89 OxoGdeHyase_C PF16870.5 KFM64895.1 - 1.7e-20 73.3 0.1 1.8e-20 73.2 0.1 1.0 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 KFM64896.1 - 2.9e-60 203.0 0.0 4.3e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KFM64896.1 - 1.5e-41 142.4 0.0 2.3e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KFM64896.1 - 4.6e-13 49.1 0.1 1.5e-12 47.5 0.1 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal AZUL PF16558.5 KFM64897.1 - 4.3e-20 71.7 4.2 1.2e-19 70.2 3.6 2.1 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A ELL PF10390.9 KFM64897.1 - 0.038 13.5 0.2 0.13 11.8 0.0 1.8 1 1 1 2 2 2 0 RNA polymerase II elongation factor ELL ERCC4 PF02732.15 KFM64899.1 - 2.4e-05 24.6 1.8 2.8e-05 24.4 1.8 1.0 1 0 0 1 1 1 1 ERCC4 domain DUF3605 PF12239.8 KFM64899.1 - 0.27 11.5 3.0 2.3 8.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3605) SapB_1 PF05184.15 KFM64901.1 - 0.057 13.4 1.0 3.1 7.9 0.1 2.8 2 0 0 2 2 2 0 Saposin-like type B, region 1 Ipi1_N PF12333.8 KFM64902.1 - 1.6e-11 44.7 0.7 3.7e-11 43.5 0.7 1.6 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.7 KFM64902.1 - 0.084 13.5 0.8 3.5 8.3 0.1 2.9 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HTH_Tnp_Tc3_2 PF01498.18 KFM64905.1 - 4.7e-16 58.8 0.4 8.5e-16 58.0 0.4 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64905.1 - 3.6e-13 49.5 0.0 5.6e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64905.1 - 1.2e-05 25.8 4.5 0.00043 20.8 0.2 3.2 3 0 0 3 3 3 1 Homeodomain-like domain FUR PF01475.19 KFM64905.1 - 0.057 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family QVR PF17064.5 KFM64906.1 - 0.0011 19.2 6.4 0.0014 18.8 6.4 1.1 1 0 0 1 1 1 1 Sleepless protein PP2C PF00481.21 KFM64907.1 - 6.3e-36 124.3 0.0 3.9e-34 118.5 0.0 2.1 1 1 0 2 2 2 2 Protein phosphatase 2C DUF5615 PF18480.1 KFM64907.1 - 0.1 12.4 0.1 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) Forkhead PF00250.18 KFM64908.1 - 5.1e-18 65.1 0.2 6.5e-18 64.8 0.2 1.1 1 0 0 1 1 1 1 Forkhead domain COX17 PF05051.13 KFM64909.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Mso1_C PF14477.6 KFM64909.1 - 0.55 10.7 6.7 0.5 10.8 4.3 2.1 1 1 1 2 2 2 0 Membrane-polarising domain of Mso1 Lebercilin PF15619.6 KFM64911.1 - 0.00026 20.7 2.0 0.00032 20.4 2.0 1.0 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease FliJ PF02050.16 KFM64911.1 - 0.00083 19.6 2.0 0.0074 16.5 0.4 2.0 1 1 1 2 2 2 1 Flagellar FliJ protein DUF3450 PF11932.8 KFM64911.1 - 0.003 16.9 0.2 0.0031 16.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) APG6_N PF17675.1 KFM64911.1 - 0.012 16.1 2.4 0.016 15.8 2.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DHR10 PF18595.1 KFM64911.1 - 0.019 15.0 3.5 0.026 14.6 3.5 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF4061 PF13270.6 KFM64911.1 - 0.047 14.0 3.3 0.077 13.3 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DEAD PF00270.29 KFM64911.1 - 0.057 13.2 0.3 0.065 13.0 0.3 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase Cep57_CLD_2 PF14197.6 KFM64911.1 - 0.11 12.6 6.6 0.15 12.1 3.5 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 CAGE1 PF15066.6 KFM64911.1 - 0.28 9.8 5.5 0.33 9.6 5.5 1.0 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family Tropomyosin PF00261.20 KFM64912.1 - 0.0032 16.9 60.0 0.032 13.6 22.6 3.9 2 1 1 3 3 3 3 Tropomyosin GAS PF13851.6 KFM64912.1 - 0.0063 15.9 56.7 0.017 14.5 4.4 4.2 2 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding Filament PF00038.21 KFM64912.1 - 2.6 7.5 55.0 0.022 14.4 9.1 4.2 3 1 1 4 4 4 0 Intermediate filament protein DUF3584 PF12128.8 KFM64912.1 - 4.3 4.7 54.0 0.023 12.3 41.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 KFM64912.1 - 4.5 7.3 32.3 3.1 7.9 3.3 4.7 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.10 KFM64912.1 - 7.6 6.4 6.6 15 5.5 0.2 4.2 2 1 2 4 4 4 0 DASH complex subunit Dam1 SAM_1 PF00536.30 KFM64913.1 - 6.9e-25 87.3 0.3 1.1e-12 48.2 0.1 3.3 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM64913.1 - 4.4e-24 84.4 0.3 5.3e-10 39.3 0.1 3.4 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SIKE PF05769.11 KFM64914.1 - 5.6e-41 140.4 8.0 6.4e-41 140.3 8.0 1.1 1 0 0 1 1 1 1 SIKE family FNIP_M PF14637.6 KFM64914.1 - 0.004 17.2 0.9 0.0051 16.8 0.9 1.1 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain TAtT PF16811.5 KFM64914.1 - 0.0052 16.1 0.1 0.0063 15.8 0.1 1.1 1 0 0 1 1 1 1 TRAP transporter T-component DUF4127 PF13552.6 KFM64914.1 - 0.0088 14.7 0.9 0.011 14.4 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4127) Kinesin_assoc PF16183.5 KFM64914.1 - 0.011 15.9 3.1 0.016 15.4 3.1 1.2 1 0 0 1 1 1 0 Kinesin-associated Sec20 PF03908.13 KFM64914.1 - 0.019 14.9 5.1 0.29 11.1 1.6 2.3 1 1 1 2 2 2 0 Sec20 TolA_bind_tri PF16331.5 KFM64914.1 - 0.055 13.5 7.1 0.072 13.2 6.2 1.8 1 1 0 1 1 1 0 TolA binding protein trimerisation TMPIT PF07851.13 KFM64914.1 - 0.095 11.9 3.9 0.13 11.5 3.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein WXG100 PF06013.12 KFM64914.1 - 0.12 12.6 3.7 0.55 10.5 0.9 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG PhoU PF01895.19 KFM64914.1 - 0.24 11.9 3.0 0.27 11.7 1.0 2.0 1 1 1 2 2 2 0 PhoU domain NEMO PF11577.8 KFM64914.1 - 0.49 10.4 8.9 4 7.5 0.3 2.6 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Herpes_BLRF2 PF05812.12 KFM64914.1 - 0.6 10.3 7.0 1.7 8.8 3.0 2.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Mto2_bdg PF12808.7 KFM64914.1 - 0.62 10.4 8.9 0.86 9.9 1.9 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region LMBR1 PF04791.16 KFM64914.1 - 0.85 8.4 2.6 0.97 8.3 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2570 PF10828.8 KFM64914.1 - 0.97 9.3 6.6 0.51 10.2 3.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) FliT PF05400.13 KFM64914.1 - 1.2 10.0 7.6 0.64 10.9 2.1 2.3 2 0 0 2 2 2 0 Flagellar protein FliT NYD-SP28_assoc PF14775.6 KFM64914.1 - 2.4 8.3 7.8 1.4 9.1 2.5 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF5094 PF17015.5 KFM64914.1 - 2.9 8.0 10.8 1 9.4 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) Transferrin PF00405.17 KFM64915.1 - 5.4e-76 255.9 6.0 3.8e-60 203.8 0.9 2.7 2 1 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.7 KFM64915.1 - 3.3e-12 46.5 0.0 8.2e-12 45.2 0.0 1.6 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein MipZ PF09140.11 KFM64915.1 - 0.039 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ Sulfotransfer_1 PF00685.27 KFM64916.1 - 4.5e-57 193.6 0.9 8.4e-57 192.7 0.9 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM64916.1 - 1.6e-06 28.7 0.1 0.00094 19.6 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family DNA_pol3_delta2 PF13177.6 KFM64917.1 - 4.2e-10 39.6 0.3 2.2e-09 37.3 0.1 2.1 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KFM64917.1 - 2.2e-07 31.3 0.1 5.2e-07 30.2 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KFM64917.1 - 0.00025 20.9 0.1 0.0005 19.9 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KFM64917.1 - 0.00074 19.9 0.1 0.0041 17.5 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_5 PF07728.14 KFM64917.1 - 0.061 13.3 0.3 0.28 11.2 0.3 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KFM64917.1 - 0.2 11.4 1.6 3.1 7.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain Clat_adaptor_s PF01217.20 KFM64918.1 - 1.1e-58 197.2 1.6 1.2e-58 197.0 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 KFM64918.1 - 0.00079 18.1 0.3 0.00096 17.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) Pet191_N PF10203.9 KFM64919.1 - 3.7e-22 78.4 6.0 4.5e-22 78.1 6.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DDE_3 PF13358.6 KFM64920.1 - 3.6e-08 33.3 0.0 5.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64920.1 - 1.4e-05 25.2 0.3 3.2e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 Transposase FhuF PF06276.12 KFM64920.1 - 0.00022 21.7 0.2 0.0012 19.2 0.2 2.0 1 1 0 1 1 1 1 Ferric iron reductase FhuF-like transporter ecTbetaR2 PF08917.10 KFM64920.1 - 0.075 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain MFS_1 PF07690.16 KFM64921.1 - 1.1e-17 64.0 14.6 1.1e-17 64.0 14.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM64921.1 - 2.3e-15 56.4 8.7 2.6e-15 56.2 8.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 KFM64921.1 - 7.5e-06 25.1 1.6 7.8e-06 25.0 1.6 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_4 PF06779.14 KFM64921.1 - 6.3e-05 22.4 5.3 8.1e-05 22.1 5.3 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KFM64921.1 - 1 7.8 11.9 0.045 12.3 4.6 1.9 1 1 1 2 2 2 0 MFS/sugar transport protein MFS_1 PF07690.16 KFM64922.1 - 5.4e-13 48.6 8.3 9.3e-11 41.2 3.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Pentapeptide_4 PF13599.6 KFM64922.1 - 1.2e-07 31.8 13.3 2.4e-07 30.8 12.9 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Sugar_tr PF00083.24 KFM64922.1 - 2.8e-06 26.5 7.0 2.8e-06 26.5 7.0 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Pentapeptide PF00805.22 KFM64922.1 - 0.011 15.4 4.5 1.4 8.6 0.1 2.7 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) DUF3624 PF12292.8 KFM64922.1 - 0.021 15.3 0.5 0.077 13.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) TMEMspv1-c74-12 PF11044.8 KFM64922.1 - 1.7 8.7 5.7 2.2 8.3 0.2 2.7 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DDE_3 PF13358.6 KFM64923.1 - 7.9e-09 35.4 0.0 9e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease N2227 PF07942.12 KFM64924.1 - 1.5e-100 335.8 0.0 1.9e-100 335.6 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_29 PF03141.16 KFM64924.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Proteasome PF00227.26 KFM64925.1 - 5.6e-30 104.2 0.0 7e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-rbx1 PF12678.7 KFM64926.1 - 8.7e-26 90.0 12.9 1.1e-25 89.6 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFM64926.1 - 6e-13 48.7 8.1 7.3e-13 48.4 8.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFM64926.1 - 6.8e-07 29.5 15.0 4.1e-05 23.8 15.0 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM64926.1 - 3.3e-05 23.6 3.2 3.3e-05 23.6 3.2 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM64926.1 - 0.00057 19.7 12.3 0.013 15.4 12.3 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFM64926.1 - 0.036 13.7 5.0 0.036 13.7 5.0 2.4 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KFM64926.1 - 0.044 13.6 11.5 0.19 11.6 4.7 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KFM64926.1 - 0.11 12.7 9.2 0.91 9.7 9.2 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 KFM64926.1 - 0.12 12.2 16.1 16 5.4 16.1 2.6 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KFM64926.1 - 0.24 11.5 8.3 1.1 9.4 8.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KFM64926.1 - 3.4 7.7 13.0 38 4.4 13.0 2.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM64926.1 - 4 7.7 9.5 0.49 10.6 0.7 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Citrate_synt PF00285.21 KFM64927.1 - 2.2e-102 342.8 0.0 2.7e-102 342.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PAS_3 PF08447.12 KFM64927.1 - 0.026 14.8 0.2 0.34 11.2 0.0 2.5 3 0 0 3 3 3 0 PAS fold HTH_Tnp_Tc3_2 PF01498.18 KFM64929.1 - 5.3e-12 45.8 7.0 1.2e-11 44.7 7.0 1.6 1 0 0 1 1 1 1 Transposase HTH_12 PF08461.10 KFM64929.1 - 0.00083 19.3 0.3 0.0015 18.5 0.3 1.4 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_32 PF13565.6 KFM64929.1 - 0.013 16.1 0.8 0.013 16.1 0.8 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Lys PF00062.20 KFM64933.1 - 9.4e-25 87.3 2.6 1.2e-24 87.0 2.6 1.1 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.20 KFM64933.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Transglycosylase SLT domain zf-H2C2_2 PF13465.6 KFM64934.1 - 1.2e-53 177.3 75.8 9.1e-08 32.2 1.5 10.2 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64934.1 - 1.1e-34 116.9 97.7 4.2e-06 26.9 1.7 9.2 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64934.1 - 3e-25 86.7 86.9 0.00058 20.5 1.1 9.2 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM64934.1 - 5.1e-21 74.4 76.3 0.00091 19.5 0.9 9.3 9 0 0 9 9 9 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64934.1 - 9.9e-16 57.6 62.2 0.0065 16.7 0.5 9.5 9 0 0 9 9 9 8 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM64934.1 - 1.2e-09 37.9 22.3 0.24 11.3 0.1 7.6 1 1 7 8 8 8 4 GAGA factor zf-C2H2_6 PF13912.6 KFM64934.1 - 4.5e-09 36.1 71.9 0.012 15.6 0.8 9.4 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM64934.1 - 0.0006 19.6 41.2 0.0089 15.9 0.5 8.7 9 0 0 9 9 9 2 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM64934.1 - 0.00062 19.8 35.3 1.5 8.9 0.3 8.9 9 1 1 10 10 10 3 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM64934.1 - 0.0049 16.7 39.8 1 9.2 0.2 8.2 3 3 5 8 8 8 2 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM64934.1 - 0.0059 16.7 45.5 1.4 9.1 0.3 9.2 8 1 1 9 9 9 1 DBF zinc finger C1_1 PF00130.22 KFM64934.1 - 0.0084 16.0 58.0 2.2 8.2 14.0 6.4 3 2 2 5 5 5 4 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.6 KFM64934.1 - 0.02 14.6 63.3 0.1 12.4 0.7 8.6 9 0 0 9 9 8 0 C2H2-type zinc-finger domain Baculo_IE-1 PF05290.11 KFM64934.1 - 0.028 14.4 37.2 3.9 7.4 0.2 7.5 1 1 4 5 5 5 0 Baculovirus immediate-early protein (IE-0) BolA PF01722.18 KFM64934.1 - 0.029 14.6 23.5 14 6.0 0.9 6.7 1 1 7 8 8 8 0 BolA-like protein zf-C2H2_11 PF16622.5 KFM64934.1 - 0.046 13.5 0.2 0.046 13.5 0.2 8.8 9 0 0 9 9 9 0 zinc-finger C2H2-type zf-RRPl_C4 PF17026.5 KFM64934.1 - 0.046 13.8 40.6 0.32 11.1 11.8 3.5 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM64934.1 - 0.076 13.2 38.1 25 5.1 0.5 9.0 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4764 PF15961.5 KFM64934.1 - 0.67 8.6 19.0 0.64 8.6 1.4 3.8 2 2 2 4 4 4 0 Domain of unknown function (DUF4764) Sprouty PF05210.13 KFM64934.1 - 1.5 9.2 32.7 0.83 10.1 4.1 4.5 4 1 0 4 4 4 0 Sprouty protein (Spry) zf-C2H2_2 PF12756.7 KFM64934.1 - 5.7 7.3 70.1 6.7 7.1 0.6 7.6 1 1 5 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 KFM64934.1 - 6.6 7.1 49.1 0.2 12.0 2.5 5.5 1 1 4 5 5 5 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFM64934.1 - 8.9 7.1 39.7 1.4 9.7 3.8 5.0 1 1 2 4 4 4 0 zinc-ribbon family zf-H2C2_2 PF13465.6 KFM64935.1 - 2.7e-119 384.8 137.0 3.1e-09 36.8 2.0 19.8 20 0 0 20 20 20 19 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64935.1 - 1.3e-77 252.1 153.1 4.5e-06 26.8 3.8 18.9 19 0 0 19 19 19 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64935.1 - 7.3e-54 175.8 141.7 0.0027 18.4 1.0 18.0 19 0 0 19 19 18 17 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM64935.1 - 1e-26 92.4 113.8 0.00057 19.8 0.4 17.6 18 0 0 18 18 18 13 C2H2-type zinc finger zf-met PF12874.7 KFM64935.1 - 1.7e-25 88.6 118.8 0.0074 16.6 0.5 17.6 17 0 0 17 17 17 11 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM64935.1 - 7.4e-24 83.2 93.3 0.0075 16.0 0.6 17.5 17 0 0 17 17 17 13 C2H2-type zinc-finger domain GAGA PF09237.11 KFM64935.1 - 1.9e-18 66.0 37.5 0.008 16.0 0.3 12.9 3 2 13 16 16 16 6 GAGA factor zf-C2H2_jaz PF12171.8 KFM64935.1 - 1e-14 54.4 94.6 0.2 12.0 0.4 17.4 17 1 0 17 17 17 9 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM64935.1 - 3e-11 43.0 62.0 1.9 8.4 0.2 16.5 5 3 12 17 17 17 4 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM64935.1 - 5e-06 26.7 21.1 3.1 8.1 0.1 9.2 4 1 5 11 11 11 2 BolA-like protein Tox-HNH-HHH PF15637.6 KFM64935.1 - 5.8e-06 26.4 6.5 10 6.4 0.0 6.9 2 2 8 10 10 10 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2HC_2 PF13913.6 KFM64935.1 - 0.0024 17.7 57.4 7.8 6.5 0.1 14.7 14 0 0 14 14 14 1 zinc-finger of a C2HC-type DUF3338 PF11819.8 KFM64935.1 - 0.0087 16.0 4.2 33 4.4 0.0 5.9 2 2 4 6 6 6 0 Domain of unknown function (DUF3338) zf-Sec23_Sec24 PF04810.15 KFM64935.1 - 0.027 14.5 57.7 20 5.4 0.2 14.1 10 2 4 14 14 14 0 Sec23/Sec24 zinc finger YiiD_C PF09500.10 KFM64935.1 - 0.09 12.6 0.0 0.35 10.7 0.0 2.0 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) zf-RRPl_C4 PF17026.5 KFM64935.1 - 0.18 12.0 74.2 0.15 12.2 8.2 7.6 1 1 6 7 7 7 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_2 PF12756.7 KFM64935.1 - 0.21 11.9 118.7 2.7 8.4 7.9 16.2 1 1 15 16 16 16 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFM64935.1 - 1.1 9.2 93.5 0.48 10.3 2.1 14.6 5 3 9 14 14 14 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.6 KFM64936.1 - 1.8e-25 88.1 36.0 4.7e-11 42.6 0.5 5.9 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64936.1 - 9.5e-23 79.3 44.5 2.6e-06 27.6 2.2 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64936.1 - 1.4e-16 59.7 40.8 0.00015 22.3 1.3 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM64936.1 - 6.5e-11 42.0 36.4 0.00055 19.9 1.1 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KFM64936.1 - 6e-07 29.6 35.5 0.15 12.5 1.4 5.6 5 1 0 5 5 5 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64936.1 - 1.1e-06 28.7 27.6 0.011 16.0 1.8 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM64936.1 - 0.00041 20.2 12.4 0.14 12.1 0.0 5.3 5 0 0 5 5 5 1 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM64936.1 - 0.046 13.7 12.6 0.14 12.2 3.3 3.5 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KFM64936.1 - 0.057 13.5 19.3 2.6 8.2 0.1 5.5 5 1 0 5 5 5 0 Sec23/Sec24 zinc finger PDDEXK_4 PF14281.6 KFM64936.1 - 0.06 13.5 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily zf-trcl PF13451.6 KFM64936.1 - 0.12 12.3 0.1 0.12 12.3 0.1 4.7 5 0 0 5 5 5 0 Probable zinc-ribbon domain zf-H2C2_5 PF13909.6 KFM64936.1 - 0.14 11.9 33.1 0.52 10.1 0.9 5.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf_UBZ PF18439.1 KFM64936.1 - 0.2 11.3 21.8 1.4 8.6 1.2 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Zf_RING PF16744.5 KFM64936.1 - 0.3 11.2 27.0 0.1 12.7 4.8 4.7 1 1 4 5 5 5 0 KIAA1045 RING finger Zn-ribbon_8 PF09723.10 KFM64936.1 - 0.34 11.1 21.6 0.4 10.8 2.9 4.3 2 2 2 4 4 4 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 KFM64936.1 - 0.53 10.2 20.7 0.47 10.3 0.4 4.0 1 1 2 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFM64936.1 - 0.65 10.4 39.2 0.9 9.9 2.3 4.9 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-CCHC_2 PF13696.6 KFM64936.1 - 0.71 9.7 26.3 0.66 9.9 0.8 5.5 5 0 0 5 5 5 0 Zinc knuckle FYVE PF01363.21 KFM64936.1 - 1.1 9.4 31.3 1.8e+04 -4.6 31.3 3.3 1 1 0 1 1 0 0 FYVE zinc finger zf-RRPl_C4 PF17026.5 KFM64936.1 - 1.5 8.9 28.1 0.032 14.3 12.5 2.2 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-H2C2_2 PF13465.6 KFM64937.1 - 4.7e-25 86.8 30.8 2.1e-07 31.0 0.7 6.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM64937.1 - 9.3e-21 73.1 28.1 0.00015 22.0 0.4 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM64937.1 - 5.1e-19 67.3 29.4 0.00065 20.3 1.0 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM64937.1 - 3.8e-14 52.3 24.9 0.00038 20.4 1.0 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM64937.1 - 1.3e-10 41.3 26.5 0.00086 19.6 2.2 5.2 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM64937.1 - 3.5e-10 39.9 26.2 0.008 16.4 2.9 5.6 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM64937.1 - 4.1e-06 27.0 20.3 0.026 14.8 1.0 4.0 2 2 2 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KFM64937.1 - 4.3e-05 23.0 20.5 0.18 11.4 0.3 5.0 1 1 4 5 5 5 2 MYST family zinc finger domain zf_UBZ PF18439.1 KFM64937.1 - 0.00058 19.4 11.3 0.55 9.9 0.1 5.0 5 0 0 5 5 5 1 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM64937.1 - 0.0016 18.3 11.9 0.078 12.9 0.3 5.0 5 0 0 5 5 5 1 zinc-finger of a C2HC-type GAGA PF09237.11 KFM64937.1 - 0.0022 17.8 5.7 0.22 11.4 0.0 3.1 2 2 1 3 3 3 2 GAGA factor C1_1 PF00130.22 KFM64937.1 - 0.0037 17.1 17.4 0.088 12.7 1.2 4.2 2 1 2 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KFM64937.1 - 0.0086 16.0 10.1 0.017 15.1 0.8 3.6 2 2 0 2 2 2 1 Adenylate kinase, active site lid Zf_RING PF16744.5 KFM64937.1 - 0.011 15.8 16.5 3.6 7.8 0.5 4.9 1 1 4 5 5 5 0 KIAA1045 RING finger zinc_ribbon_15 PF17032.5 KFM64937.1 - 0.013 16.2 14.4 0.13 13.0 2.3 2.9 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM64937.1 - 0.021 15.2 22.4 2.3 8.6 1.7 4.1 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Rpr2 PF04032.16 KFM64937.1 - 0.025 14.9 17.1 0.026 14.8 0.8 3.2 1 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mga PF05043.13 KFM64937.1 - 0.025 15.1 0.6 0.12 12.9 0.1 2.0 2 1 0 2 2 2 0 Mga helix-turn-helix domain HNH_5 PF14279.6 KFM64937.1 - 0.027 14.3 17.4 0.027 14.3 0.8 4.6 2 1 2 4 4 4 0 HNH endonuclease zf-RRPl_C4 PF17026.5 KFM64937.1 - 0.032 14.3 16.0 0.51 10.5 5.7 2.3 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 KFM64937.1 - 0.034 14.2 12.7 0.12 12.5 0.4 3.6 2 1 3 5 5 5 0 Zinc ribbon domain Vps36-NZF-N PF16988.5 KFM64937.1 - 0.047 13.1 6.9 0.061 12.7 0.1 3.1 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 KFM64937.1 - 0.096 12.7 11.6 1.1e+02 2.9 11.6 3.3 1 1 0 1 1 1 0 Double zinc ribbon C1_4 PF07975.12 KFM64937.1 - 0.15 12.3 16.5 0.22 11.8 0.9 3.7 2 1 1 3 3 3 0 TFIIH C1-like domain HypA PF01155.19 KFM64937.1 - 0.2 11.7 8.8 0.54 10.3 5.1 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE PF01363.21 KFM64937.1 - 0.28 11.3 18.1 14 5.9 13.3 3.2 1 1 1 2 2 2 0 FYVE zinc finger zf_Hakai PF18408.1 KFM64937.1 - 0.37 10.5 13.1 2.3 8.0 0.3 4.1 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain Mut7-C PF01927.16 KFM64937.1 - 0.38 10.9 11.7 0.42 10.7 5.9 3.1 1 1 1 2 2 2 0 Mut7-C RNAse domain DUF3268 PF11672.8 KFM64937.1 - 0.78 10.1 14.2 1.1 9.6 1.8 2.7 1 1 2 3 3 3 0 zinc-finger-containing domain XPA_N PF01286.18 KFM64937.1 - 1.2 9.2 12.1 19 5.4 0.3 4.6 5 0 0 5 5 5 0 XPA protein N-terminal zf-C2H2_9 PF16293.5 KFM64937.1 - 1.2 9.0 12.8 6.7 6.6 0.3 3.6 3 1 1 4 4 3 0 C2H2 type zinc-finger (1 copy) DUF629 PF04780.12 KFM64937.1 - 1.6 7.2 20.3 0.18 10.3 1.2 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF629) zf-met2 PF12907.7 KFM64937.1 - 3.6 7.8 20.0 6.9 6.9 0.6 4.7 5 0 0 5 5 5 0 Zinc-binding zf_C2H2_ZHX PF18387.1 KFM64937.1 - 6.8 6.4 21.7 1.7 8.3 0.2 4.9 1 1 4 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain Pepdidase_M14_N PF18027.1 KFM64938.1 - 1.2e-14 54.5 1.2 2.8e-14 53.4 1.2 1.7 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KFM64938.1 - 5.9e-11 42.7 0.0 2e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KFM64938.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family TMEM126 PF07114.11 KFM64942.1 - 0.0087 15.5 0.3 0.0092 15.4 0.3 1.0 1 0 0 1 1 1 1 Transmembrane protein 126 AMMECR1 PF01871.17 KFM64943.1 - 7.3e-35 120.0 0.0 8.3e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 NAD_binding_2 PF03446.15 KFM64947.1 - 1.5e-34 119.5 0.1 3.4e-34 118.3 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PWWP PF00855.17 KFM64947.1 - 3.2e-19 69.1 0.1 8.3e-19 67.8 0.1 1.8 1 0 0 1 1 1 1 PWWP domain NAD_binding_11 PF14833.6 KFM64947.1 - 7.7e-13 48.8 0.3 1.6e-12 47.8 0.3 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFM64947.1 - 1.8e-09 38.0 0.1 1e-08 35.6 0.1 2.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KFM64947.1 - 2.7e-07 30.1 0.0 4.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFM64947.1 - 5.6e-07 29.7 0.2 3.1e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KFM64947.1 - 0.0001 22.0 0.1 0.00019 21.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 KFM64947.1 - 0.0016 18.3 0.1 0.0058 16.5 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding NAD_binding_7 PF13241.6 KFM64947.1 - 0.0026 18.2 2.3 0.033 14.6 0.0 3.2 3 0 0 3 3 3 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KFM64947.1 - 0.0051 17.1 0.1 0.016 15.4 0.1 1.9 2 0 0 2 2 1 1 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 KFM64947.1 - 0.0072 15.9 0.0 0.04 13.5 0.0 2.1 1 1 1 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 KFM64947.1 - 0.015 15.3 0.2 0.033 14.2 0.0 1.7 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KFM64947.1 - 0.016 15.5 0.0 0.043 14.1 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KFM64947.1 - 0.018 15.0 0.0 0.018 15.0 0.0 2.7 3 1 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FlaC_arch PF05377.11 KFM64947.1 - 0.11 13.0 2.7 0.14 12.6 0.6 2.3 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Apolipoprotein PF01442.18 KFM64947.1 - 0.13 12.2 4.7 0.047 13.6 1.8 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phasin PF05597.11 KFM64947.1 - 0.26 11.3 4.9 0.12 12.3 1.3 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fib_alpha PF08702.10 KFM64947.1 - 2.9 8.1 6.4 2.1 8.6 0.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tnp_22_trimer PF17489.2 KFM64947.1 - 4.5 7.3 8.3 3.6 7.6 0.4 3.7 3 1 1 4 4 4 0 L1 transposable element trimerization domain STI1 PF17830.1 KFM64948.1 - 1.4e-12 47.4 38.3 0.00086 19.2 1.7 5.7 3 2 2 5 5 5 5 STI1 domain UBA PF00627.31 KFM64948.1 - 1.3e-05 25.0 0.2 5e-05 23.1 0.2 2.2 1 0 0 1 1 1 1 UBA/TS-N domain Uteroglobin PF01099.17 KFM64948.1 - 0.085 13.2 0.0 0.31 11.4 0.0 2.0 1 0 0 1 1 1 0 Uteroglobin family ComX PF05952.12 KFM64948.1 - 5.1 7.1 15.5 17 5.4 0.5 5.8 5 1 1 6 6 6 0 Bacillus competence pheromone ComX Symplekin_C PF12295.8 KFM64948.1 - 5.3 7.1 7.7 0.66 10.0 0.7 2.8 2 2 1 3 3 3 0 Symplekin tight junction protein C terminal HTH_Tnp_Tc3_2 PF01498.18 KFM64949.1 - 2.4e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64949.1 - 9.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64950.1 - 2.5e-16 59.7 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64950.1 - 1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64950.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64950.1 - 0.0024 17.6 0.6 0.0069 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64950.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64951.1 - 5.1e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64951.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64951.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64951.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64951.1 - 2.4 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain PfkB PF00294.24 KFM64954.1 - 2.4e-06 27.1 0.1 2.4e-06 27.1 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HTH_Tnp_Tc3_2 PF01498.18 KFM64955.1 - 2.6e-10 40.4 5.9 5e-10 39.5 5.9 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64955.1 - 3.7e-10 39.7 0.0 4.5e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64955.1 - 0.001 19.6 4.1 0.001 19.6 4.1 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_12 PF08461.10 KFM64955.1 - 0.019 14.9 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_48 PF17906.1 KFM64956.1 - 3.2e-08 33.6 0.0 5.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM64956.1 - 1.5e-06 28.7 6.3 3.3e-05 24.4 4.0 3.1 3 1 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64956.1 - 0.0021 18.3 0.5 0.0057 16.9 0.5 1.8 1 0 0 1 1 1 1 Transposase HTH_17 PF12728.7 KFM64956.1 - 0.08 13.1 0.1 4.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.7 KFM64956.1 - 0.089 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 KFM64956.1 - 0.11 12.7 0.4 7.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain PCI PF01399.27 KFM64956.1 - 0.16 12.5 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 PCI domain Sigma70_r4 PF04545.16 KFM64956.1 - 0.18 11.4 0.8 0.64 9.6 0.3 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 CoaE PF01121.20 KFM64958.1 - 2.6e-60 203.2 0.0 3e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KFM64958.1 - 0.00029 21.4 0.5 0.0056 17.2 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFM64958.1 - 0.012 16.0 0.0 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain RAMA PF18755.1 KFM64958.1 - 0.057 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Restriction Enzyme Adenine Methylase Associated TMPIT PF07851.13 KFM64959.1 - 9.1e-127 422.8 10.7 1e-126 422.6 10.7 1.0 1 0 0 1 1 1 1 TMPIT-like protein Seryl_tRNA_N PF02403.22 KFM64959.1 - 0.00062 20.0 2.8 0.002 18.3 2.1 1.9 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF4079 PF13301.6 KFM64959.1 - 0.0046 17.1 0.1 0.0088 16.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) Lebercilin PF15619.6 KFM64959.1 - 0.0055 16.4 2.3 0.0075 16.0 2.3 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Sec34 PF04136.15 KFM64959.1 - 0.0098 15.8 0.6 0.019 14.9 0.6 1.4 1 0 0 1 1 1 1 Sec34-like family EzrA PF06160.12 KFM64959.1 - 0.011 14.0 3.2 0.047 11.9 0.5 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 KFM64959.1 - 0.031 14.5 1.1 0.047 13.9 1.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KFM64959.1 - 0.048 11.2 0.3 0.059 10.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 KFM64959.1 - 0.094 11.3 2.0 0.11 11.1 2.0 1.1 1 0 0 1 1 1 0 AAA domain HMMR_N PF15905.5 KFM64959.1 - 0.11 11.9 4.3 0.17 11.3 4.0 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 KFM64959.1 - 1.6 8.8 3.8 0.4 10.7 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 KFM64960.1 - 8.1e-07 29.3 5.4 9.9e-07 29.0 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1664 PF07889.12 KFM64960.1 - 0.00017 21.7 2.9 0.00025 21.0 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 KFM64960.1 - 0.00051 20.0 2.7 0.00061 19.7 2.7 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 KFM64960.1 - 0.0014 18.9 2.1 0.0017 18.6 2.1 1.0 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Spore_III_AB PF09548.10 KFM64960.1 - 0.0081 16.3 3.2 0.0097 16.0 3.2 1.1 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Baculo_PEP_C PF04513.12 KFM64960.1 - 0.0081 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 KFM64960.1 - 0.013 15.4 6.0 0.013 15.4 6.0 1.6 1 1 0 1 1 1 0 CdvA-like coiled-coil domain NPV_P10 PF05531.12 KFM64960.1 - 0.015 15.7 0.3 0.056 13.9 0.2 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1351 PF07083.11 KFM64960.1 - 0.015 15.1 7.8 0.019 14.7 7.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) CHASE3 PF05227.13 KFM64960.1 - 0.028 14.3 0.3 0.056 13.4 0.1 1.5 1 1 0 1 1 1 0 CHASE3 domain MIS13 PF08202.11 KFM64960.1 - 0.028 13.7 2.2 0.032 13.5 2.2 1.0 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Med11 PF10280.9 KFM64960.1 - 0.036 14.5 0.8 0.039 14.4 0.8 1.1 1 0 0 1 1 1 0 Mediator complex protein Spectrin PF00435.21 KFM64960.1 - 0.042 14.3 4.8 0.18 12.3 3.1 2.0 1 1 1 2 2 2 0 Spectrin repeat DUF3584 PF12128.8 KFM64960.1 - 0.044 11.3 4.5 0.057 10.9 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HrpB7 PF09486.10 KFM64960.1 - 0.047 14.1 4.4 0.16 12.3 4.4 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Fzo_mitofusin PF04799.13 KFM64960.1 - 0.049 13.2 4.8 0.095 12.3 4.8 1.5 1 1 0 1 1 1 0 fzo-like conserved region COMP PF11598.8 KFM64960.1 - 0.052 14.0 1.9 10 6.7 0.2 2.9 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein DUF148 PF02520.17 KFM64960.1 - 0.083 13.0 5.2 1 9.5 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 ApoLp-III PF07464.11 KFM64960.1 - 0.084 13.0 5.6 0.15 12.1 5.6 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4795 PF16043.5 KFM64960.1 - 0.12 11.9 7.5 0.16 11.6 6.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Golgin_A5 PF09787.9 KFM64960.1 - 0.13 11.8 5.6 0.14 11.6 5.6 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Seryl_tRNA_N PF02403.22 KFM64960.1 - 0.14 12.4 8.9 0.33 11.2 8.9 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 KFM64960.1 - 0.15 12.1 5.3 0.67 10.0 4.2 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BshC PF10079.9 KFM64960.1 - 0.17 10.6 5.5 0.2 10.3 5.5 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF4449 PF14613.6 KFM64960.1 - 0.23 11.6 7.0 0.67 10.1 7.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4449) FlaC_arch PF05377.11 KFM64960.1 - 0.23 11.9 6.1 3.4 8.1 0.1 3.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) tRNA_bind_2 PF13725.6 KFM64960.1 - 0.24 11.1 6.2 0.26 11.0 6.2 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain YojJ PF10372.9 KFM64960.1 - 0.47 10.6 3.5 0.88 9.7 2.0 2.3 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus UBN_AB PF14075.6 KFM64960.1 - 0.53 10.0 7.1 2.6 7.7 7.1 1.8 1 1 0 1 1 1 0 Ubinuclein conserved middle domain ABC_tran_CTD PF16326.5 KFM64960.1 - 0.7 10.2 0.1 0.7 10.2 0.1 2.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain TMPIT PF07851.13 KFM64960.1 - 1 8.6 4.0 1.1 8.5 4.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Mt_ATP-synt_D PF05873.12 KFM64960.1 - 1.4 8.8 9.8 4.1 7.2 9.8 1.8 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) HTH_Tnp_Tc3_2 PF01498.18 KFM64961.1 - 2.1e-19 69.5 3.6 5.6e-19 68.2 2.1 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64961.1 - 4.6e-16 58.9 0.0 2.2e-15 56.7 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM64961.1 - 2.1e-07 30.9 0.4 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM64961.1 - 3.5e-07 30.7 2.0 3.5e-07 30.7 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64961.1 - 9.1e-07 28.9 2.3 7.5e-05 22.8 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64961.1 - 1.8e-06 27.6 3.4 2.5e-05 23.9 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM64961.1 - 2.7e-06 27.3 0.7 3.9e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM64961.1 - 7.1e-05 22.6 0.7 0.0017 18.2 0.0 2.9 3 1 1 4 4 4 1 MarR family HTH_Crp_2 PF13545.6 KFM64961.1 - 0.001 19.0 0.3 0.016 15.2 0.0 2.4 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM64961.1 - 0.02 14.6 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM64961.1 - 0.043 13.9 0.0 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM64961.1 - 0.071 13.3 0.2 12 6.1 0.0 2.8 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM64961.1 - 0.13 11.8 0.2 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM64961.1 - 0.15 12.1 0.0 29 4.8 0.0 2.6 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM64961.1 - 0.27 11.0 3.9 1.4 8.7 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_11 PF08279.12 KFM64961.1 - 0.43 10.6 1.7 51 3.9 0.2 3.3 3 0 0 3 3 3 0 HTH domain HTH_Tnp_ISL3 PF13542.6 KFM64961.1 - 1.1 8.8 3.6 7 6.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 RVT_1 PF00078.27 KFM64962.1 - 2.1e-42 145.2 0.0 3.5e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM64962.1 - 4.2e-17 62.1 0.0 1.2e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KFM64962.1 - 3e-12 46.9 0.0 5.9e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 KFM64962.1 - 8e-08 32.1 0.0 2.1e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.6 KFM64962.1 - 0.034 14.0 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like ANF_receptor PF01094.28 KFM64963.1 - 1.2e-06 27.9 0.0 1.4e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region HTH_Tnp_Tc3_2 PF01498.18 KFM64964.1 - 4.6e-16 58.8 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64964.1 - 3.1e-13 49.7 0.0 5.3e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64964.1 - 1.9e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64964.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64964.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ANF_receptor PF01094.28 KFM64965.1 - 2.5e-14 53.1 0.0 2.9e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region HTH_Tnp_Tc3_2 PF01498.18 KFM64966.1 - 3.5e-16 59.2 3.0 6.2e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM64966.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM64966.1 - 3.2e-07 30.0 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM64966.1 - 0.0029 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM64966.1 - 2.6 8.7 15.6 0.13 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain PDZ PF00595.24 KFM64967.1 - 1.6e-09 38.0 1.8 2.1e-09 37.6 0.5 1.8 2 0 0 2 2 2 1 PDZ domain L27 PF02828.16 KFM64967.1 - 8.3e-09 35.1 1.9 0.00066 19.4 0.0 2.6 2 0 0 2 2 2 2 L27 domain PDZ_6 PF17820.1 KFM64967.1 - 3.4e-07 30.0 0.2 8.2e-07 28.8 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM64967.1 - 0.00057 20.2 0.3 0.0019 18.5 0.3 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM64968.1 - 0.00062 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM64968.1 - 0.022 15.1 0.0 0.066 13.6 0.0 1.8 2 0 0 2 2 2 0 PDZ domain HTH_Tnp_Tc3_2 PF01498.18 KFM64969.1 - 2e-16 60.0 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64969.1 - 8.3e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease TED_complement PF07678.14 KFM64970.1 - 1.1e-99 333.4 0.0 1.7e-99 332.8 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFM64970.1 - 4.8e-29 101.5 8.5 4.1e-27 95.3 1.5 4.3 4 1 1 5 5 5 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFM64970.1 - 1.4e-26 92.1 0.5 8.3e-26 89.7 0.1 2.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFM64970.1 - 2.8e-25 88.8 0.4 1e-24 87.1 0.4 2.1 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG3 PF17791.1 KFM64970.1 - 2.7e-17 62.8 0.5 5.4e-16 58.6 0.2 3.3 3 0 0 3 3 3 1 Macroglobulin domain MG3 MG2 PF01835.19 KFM64970.1 - 6.3e-15 55.4 0.0 5.7e-14 52.3 0.0 2.8 2 0 0 2 2 2 1 MG2 domain SQHop_cyclase_C PF13243.6 KFM64970.1 - 3.7e-05 23.0 0.1 0.00084 18.5 0.0 2.2 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KFM64970.1 - 0.00035 20.2 0.0 1.3 8.9 0.0 2.8 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat MG4 PF17789.1 KFM64970.1 - 0.0019 18.3 0.3 0.089 13.0 0.0 4.1 4 1 0 4 4 4 1 Macroglobulin domain MG4 Methyltransf_11 PF08241.12 KFM64971.1 - 5.9e-18 65.3 0.0 5.1e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM64971.1 - 6.7e-17 61.8 0.0 9.9e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM64971.1 - 1.5e-12 48.0 0.0 1.6e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM64971.1 - 2.8e-10 40.2 0.0 3.5e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM64971.1 - 3.9e-10 40.3 0.0 6.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM64971.1 - 4.1e-09 36.1 0.0 6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KFM64971.1 - 7.6e-06 25.9 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MGDG_synth PF06925.11 KFM64971.1 - 0.033 14.3 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase Sugar_tr PF00083.24 KFM64973.1 - 3e-37 128.5 12.6 4.7e-37 127.9 12.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM64973.1 - 4.4e-30 104.8 48.1 3.3e-26 92.1 32.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFM64973.1 - 0.0011 17.5 1.1 0.0018 16.8 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KFM64973.1 - 0.0053 15.4 14.6 0.11 11.0 4.7 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein DDE_3 PF13358.6 KFM64974.1 - 5.3e-16 58.7 0.1 6.1e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64974.1 - 8.1e-16 58.0 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM64974.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM64974.1 - 0.0027 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64974.1 - 0.016 15.3 0.1 0.066 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM64974.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM64975.1 - 4.6e-16 58.9 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64975.1 - 7.6e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM64975.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM64975.1 - 0.0017 18.1 0.0 0.079 12.8 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64975.1 - 0.014 15.6 0.1 0.058 13.5 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM64975.1 - 0.022 14.8 2.1 0.031 14.3 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM64975.1 - 0.097 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase Peptidase_M48_N PF16491.5 KFM64976.1 - 8.5e-67 224.6 8.1 8.5e-67 224.6 8.1 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KFM64976.1 - 8.1e-54 182.4 0.6 1.4e-53 181.6 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M48 OAD_gamma PF04277.13 KFM64976.1 - 0.092 13.3 0.4 0.092 13.3 0.4 2.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain 5_nucleotid_C PF02872.18 KFM64977.1 - 4.9e-42 143.8 0.0 6.6e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Tropomodulin PF03250.14 KFM64977.1 - 0.067 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Tropomodulin NicO PF03824.16 KFM64978.1 - 0.097 12.0 0.7 0.12 11.7 0.7 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein DDE_3 PF13358.6 KFM64979.1 - 4.2e-10 39.6 0.0 5.7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM64980.1 - 1.3e-14 54.2 0.6 2.2e-14 53.4 0.6 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64980.1 - 3e-09 36.8 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64980.1 - 0.0012 19.4 0.9 0.0012 19.4 0.9 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM64981.1 - 6.9e-16 58.3 0.7 1.2e-15 57.5 0.7 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64981.1 - 1.9e-07 30.9 0.0 0.00049 19.9 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_32 PF13565.6 KFM64981.1 - 0.0043 17.7 3.1 0.047 14.3 0.8 2.3 2 0 0 2 2 2 1 Homeodomain-like domain T-box PF00907.22 KFM64982.1 - 2.6e-07 31.1 0.0 3.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 T-box Drf_FH3 PF06367.16 KFM64984.1 - 9.1e-06 25.4 1.7 1.6e-05 24.6 1.7 1.5 1 1 0 1 1 1 1 Diaphanous FH3 Domain Seryl_tRNA_N PF02403.22 KFM64984.1 - 0.0091 16.2 0.9 0.013 15.7 0.9 1.4 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.6 KFM64984.1 - 0.0094 15.6 1.4 0.012 15.2 1.4 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HTH_Tnp_Tc3_2 PF01498.18 KFM64985.1 - 5.1e-16 58.7 6.5 7.9e-16 58.1 6.5 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM64985.1 - 0.0004 20.9 1.5 0.0004 20.9 1.5 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM64985.1 - 0.0071 16.1 2.1 0.072 12.9 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM64985.1 - 0.011 15.9 0.1 0.039 14.1 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM64985.1 - 0.032 14.3 1.0 0.032 14.3 1.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM64985.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Pex24p PF06398.11 KFM64987.1 - 0.0011 18.1 0.0 0.0011 18.1 0.0 2.7 2 1 0 2 2 2 1 Integral peroxisomal membrane peroxin Cation_efflux PF01545.21 KFM64987.1 - 0.06 13.1 5.7 0.022 14.5 2.0 2.0 2 0 0 2 2 2 0 Cation efflux family XK-related PF09815.9 KFM64988.1 - 3.4e-88 296.0 50.0 4.2e-88 295.7 50.0 1.1 1 0 0 1 1 1 1 XK-related protein WD40 PF00400.32 KFM64989.1 - 1.1e-15 57.7 15.7 1.8e-05 25.4 0.3 5.2 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM64989.1 - 2.6e-05 24.4 0.1 0.012 15.9 0.6 3.5 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM64989.1 - 3.1e-05 22.8 1.4 0.15 10.7 0.2 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KFM64989.1 - 0.00016 21.6 1.2 0.29 11.0 0.7 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ras PF00071.22 KFM64990.1 - 1e-49 168.2 0.0 1.2e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM64990.1 - 2.3e-30 105.3 0.0 3.4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM64990.1 - 4.4e-13 49.1 0.0 6e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM64990.1 - 4.8e-08 33.1 0.0 7.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM64990.1 - 7.4e-05 22.2 0.1 0.0001 21.8 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFM64990.1 - 0.00015 21.7 0.0 0.0021 18.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFM64990.1 - 0.0002 21.0 0.2 0.013 15.0 0.2 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFM64990.1 - 0.00051 19.5 0.0 0.00087 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KFM64990.1 - 0.0032 17.9 0.0 0.0072 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 KFM64990.1 - 0.011 15.5 0.1 0.034 13.9 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KFM64990.1 - 0.012 15.4 0.1 0.033 13.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFM64990.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KFM64990.1 - 0.015 15.6 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KFM64990.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Septin TniB PF05621.11 KFM64990.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 KFM64990.1 - 0.038 13.5 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KFM64990.1 - 0.045 13.6 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 KFM64990.1 - 0.093 12.3 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 KFM64990.1 - 0.12 12.8 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KFM64990.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KFM64990.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HTH_Tnp_Tc3_2 PF01498.18 KFM64991.1 - 2e-16 60.0 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM64991.1 - 8.4e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MBT PF02820.18 KFM64992.1 - 1.3e-92 304.1 4.6 4.8e-28 97.3 0.1 4.2 4 0 0 4 4 4 4 mbt repeat Innexin PF00876.18 KFM64993.1 - 2.8e-25 89.4 7.6 3.7e-25 89.0 7.6 1.1 1 0 0 1 1 1 1 Innexin Abhydrolase_1 PF00561.20 KFM64994.1 - 7.7e-18 65.1 0.0 1.6e-17 64.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM64994.1 - 2.8e-11 44.4 0.0 4.3e-11 43.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM64994.1 - 8.3e-08 31.8 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 KFM64994.1 - 0.00011 20.9 0.2 0.02 13.4 0.1 2.2 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 KFM64994.1 - 0.0019 18.0 0.1 0.38 10.4 0.1 2.1 1 1 1 2 2 2 2 PGAP1-like protein Ndr PF03096.14 KFM64994.1 - 0.0071 15.1 0.0 0.014 14.1 0.0 1.4 1 1 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 KFM64994.1 - 0.039 12.8 0.1 0.35 9.7 0.1 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 KFM64994.1 - 0.045 13.4 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 KFM64994.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFM64994.1 - 0.1 12.4 0.0 5.3 6.8 0.0 2.7 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase Innexin PF00876.18 KFM64995.1 - 1.9e-39 136.0 17.0 2.4e-39 135.6 17.0 1.1 1 0 0 1 1 1 1 Innexin Ras PF00071.22 KFM64996.1 - 4.9e-21 75.0 0.4 5.9e-21 74.7 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM64996.1 - 2e-19 69.9 0.3 2.7e-19 69.6 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM64996.1 - 8.6e-06 25.3 0.4 9.8e-06 25.1 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KFM64996.1 - 0.00088 18.8 0.1 0.001 18.7 0.1 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 KFM64996.1 - 0.002 17.6 0.0 0.0038 16.7 0.0 1.4 1 1 1 2 2 2 1 Bacterial TniB protein SRPRB PF09439.10 KFM64996.1 - 0.0037 16.7 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFM64996.1 - 0.021 14.2 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM64996.1 - 0.023 14.8 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KFM64996.1 - 0.048 13.9 0.0 0.061 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFM64996.1 - 0.091 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KFM64996.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM64996.1 - 0.13 12.6 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNase_H PF00075.24 KFM64997.1 - 0.031 14.5 0.0 0.043 14.0 0.0 1.1 1 0 0 1 1 1 0 RNase H DUF4371 PF14291.6 KFM64998.1 - 2.7e-30 105.8 0.5 5.5e-30 104.7 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM64998.1 - 1.8e-09 37.2 0.2 5.8e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Exonuc_VII_L PF02601.15 KFM64998.1 - 2.9 7.4 4.7 8.2 5.9 1.2 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit IRF-2BP1_2 PF11261.8 KFM64999.1 - 4.3e-34 115.8 1.0 9.8e-34 114.7 1.0 1.6 1 0 0 1 1 1 1 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4 PF00097.25 KFM64999.1 - 7e-05 22.6 5.2 7e-05 22.6 5.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM64999.1 - 0.00057 19.7 2.6 0.0017 18.1 2.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KFM64999.1 - 0.14 12.1 1.5 0.41 10.6 1.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KFM64999.1 - 1.2 9.5 10.5 0.18 12.1 5.8 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 KFM64999.1 - 1.9 8.4 12.7 0.042 13.7 4.6 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DDE_Tnp_4 PF13359.6 KFM65000.1 - 2.4e-31 108.5 0.0 3.5e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM65000.1 - 1e-06 28.5 0.0 2.6e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Plant transposon protein Scramblase PF03803.15 KFM65001.1 - 0.025 13.9 0.2 0.027 13.8 0.2 1.1 1 0 0 1 1 1 0 Scramblase Ig_2 PF13895.6 KFM65002.1 - 1.5e-05 25.2 1.5 0.0014 18.9 0.2 2.9 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFM65002.1 - 0.00086 19.9 4.7 0.81 10.3 0.1 3.9 3 1 1 4 4 4 2 Immunoglobulin domain Gag_p17 PF00540.18 KFM65002.1 - 0.093 12.7 0.3 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) 7tm_2 PF00002.24 KFM65003.1 - 1.4e-37 129.3 19.0 1.9e-37 128.9 19.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFM65003.1 - 9e-14 51.7 3.8 1.7e-13 50.8 3.8 1.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Aminotran_5 PF00266.19 KFM65004.1 - 6.9e-07 28.6 0.0 8.2e-07 28.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_5 PF00266.19 KFM65005.1 - 2.9e-31 108.8 1.7 1.2e-30 106.8 1.7 1.8 1 1 0 1 1 1 1 Aminotransferase class-V TBP PF00352.21 KFM65006.1 - 7.3e-56 186.1 0.3 5.2e-30 103.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFM65006.1 - 0.0014 18.7 0.0 0.84 9.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Ank_2 PF12796.7 KFM65008.1 - 7.6e-21 74.5 0.1 1e-14 54.9 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM65008.1 - 4.6e-17 62.2 0.2 3e-06 27.7 0.0 3.5 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM65008.1 - 4.9e-16 57.2 0.3 3.5e-07 30.0 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KFM65008.1 - 1.1e-15 57.5 0.0 3.1e-08 33.7 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM65008.1 - 2.4e-15 56.2 1.3 5.2e-08 33.0 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ribosomal_L10 PF00466.20 KFM65009.1 - 0.12 12.6 0.0 0.46 10.7 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L10 FTR1 PF03239.14 KFM65009.1 - 0.27 10.3 0.0 0.38 9.9 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family zf-C2H2_4 PF13894.6 KFM65009.1 - 0.31 12.0 0.4 0.31 12.0 0.4 3.3 1 1 1 2 2 2 0 C2H2-type zinc finger DDE_3 PF13358.6 KFM65011.1 - 1.8e-09 37.5 0.0 3.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65011.1 - 2.2e-06 27.8 1.9 2.2e-06 27.8 1.9 2.1 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM65011.1 - 5.3e-05 22.9 0.6 0.00016 21.4 0.6 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65011.1 - 0.00087 19.0 3.2 0.00087 19.0 3.2 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM65011.1 - 0.0075 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Tc3 transposase Sigma70_r4_2 PF08281.12 KFM65011.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.6 KFM65011.1 - 0.13 12.3 7.6 0.049 13.7 4.4 2.0 2 0 0 2 2 2 0 Winged helix-turn helix TPR_12 PF13424.6 KFM65012.1 - 9.2e-48 160.4 19.3 1.7e-09 37.8 0.1 7.1 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.6 KFM65012.1 - 5.4e-26 89.7 11.9 1.7e-06 27.7 0.1 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFM65012.1 - 4.3e-21 73.3 8.1 0.038 14.2 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFM65012.1 - 1.6e-10 40.4 10.2 1.1 9.2 0.0 8.1 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM65012.1 - 3.3e-10 39.2 3.4 0.22 11.7 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat DUF2225 PF09986.9 KFM65012.1 - 2.9e-09 37.0 6.5 0.56 9.9 0.1 6.3 1 1 5 6 6 6 4 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.17 KFM65012.1 - 6e-05 22.8 25.1 0.11 12.6 0.0 8.8 11 2 0 11 11 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM65012.1 - 0.00018 21.9 1.6 10 7.0 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM65012.1 - 0.00023 21.7 0.5 40 5.4 0.0 6.1 5 1 2 7 7 6 0 Tetratricopeptide repeat Mob_Pre PF01076.19 KFM65012.1 - 0.00029 20.7 1.1 8.5 6.1 0.0 4.6 6 0 0 6 6 6 1 Plasmid recombination enzyme Arm_3 PF16186.5 KFM65012.1 - 0.00044 19.8 2.0 0.026 14.1 0.1 3.9 5 0 0 5 5 5 1 Atypical Arm repeat ComR_TPR PF18710.1 KFM65012.1 - 0.0049 16.4 2.2 0.13 11.8 0.1 2.7 2 1 0 2 2 2 1 ComR tetratricopeptide Ribosomal_S7 PF00177.21 KFM65012.1 - 0.011 15.4 0.0 17 5.0 0.0 4.0 3 1 0 4 4 4 0 Ribosomal protein S7p/S5e TPR_4 PF07721.14 KFM65012.1 - 0.027 15.1 0.0 17 6.4 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat SPO22 PF08631.10 KFM65012.1 - 0.046 13.2 7.7 0.42 10.1 0.1 4.2 2 2 1 4 4 4 0 Meiosis protein SPO22/ZIP4 like RPN6_N PF18055.1 KFM65012.1 - 0.094 13.1 1.9 0.42 11.0 0.1 3.0 3 1 0 3 3 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain DnaB_bind PF10410.9 KFM65012.1 - 0.14 12.3 0.2 6.5 7.0 0.0 3.4 4 0 0 4 4 4 0 DnaB-helicase binding domain of primase DUF1955 PF09205.10 KFM65012.1 - 0.25 11.1 3.2 44 3.8 0.0 5.0 3 2 3 6 6 6 0 Domain of unknown function (DUF1955) Ferlin_C PF16165.5 KFM65013.1 - 0.29 11.1 2.8 0.27 11.2 2.8 1.0 1 0 0 1 1 1 0 Ferlin C-terminus ABC2_membrane_3 PF12698.7 KFM65014.1 - 9.7e-05 21.6 23.3 0.0001 21.5 23.3 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein CD52 PF15116.6 KFM65014.1 - 0.00036 20.5 1.0 0.6 10.2 0.1 2.8 2 0 0 2 2 2 2 CAMPATH-1 antigen ABC_tran PF00005.27 KFM65017.1 - 1.1e-15 58.3 0.0 1.9e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM65017.1 - 0.00034 20.5 0.0 0.0016 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Ribosomal_S8 PF00410.19 KFM65019.1 - 2e-17 63.3 0.0 3e-17 62.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 WSC PF01822.19 KFM65020.1 - 2.2e-19 69.4 4.8 4e-19 68.6 4.8 1.5 1 0 0 1 1 1 1 WSC domain Branch PF02485.21 KFM65020.1 - 4.7e-17 62.3 0.1 7.1e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Xylo_C PF12529.8 KFM65021.1 - 7.6e-42 143.0 0.0 1.4e-41 142.1 0.0 1.4 2 0 0 2 2 2 1 Xylosyltransferase C terminal Branch PF02485.21 KFM65021.1 - 7.4e-15 55.1 0.1 1.2e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme KHA PF11834.8 KFM65022.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel Pkinase PF00069.25 KFM65023.1 - 1.6e-64 217.8 0.0 1.9e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65023.1 - 2.2e-30 105.8 0.0 2.9e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM65023.1 - 2e-07 30.6 0.5 3.1e-07 30.0 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM65023.1 - 4.9e-05 22.8 0.1 9.2e-05 21.9 0.1 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFM65023.1 - 0.00036 20.2 0.3 0.00068 19.3 0.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFM65023.1 - 0.0005 20.1 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFM65023.1 - 0.019 13.9 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KFM65023.1 - 0.071 12.7 0.1 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DDE_3 PF13358.6 KFM65024.1 - 0.00014 21.7 0.1 0.00026 20.8 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HI0933_like PF03486.14 KFM65025.1 - 0.013 14.2 0.0 0.028 13.1 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KFM65025.1 - 0.022 13.6 0.0 0.18 10.6 0.0 2.2 2 1 1 3 3 3 0 Tryptophan halogenase XdhC_C PF13478.6 KFM65025.1 - 0.024 15.1 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox PF00070.27 KFM65025.1 - 0.031 14.8 0.0 0.08 13.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM65025.1 - 0.039 14.2 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFM65025.1 - 0.044 13.0 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Glyco_transf_10 PF00852.19 KFM65026.1 - 1.4e-09 37.9 0.0 2.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFM65027.1 - 1e-09 38.8 0.6 3.3e-09 37.2 0.3 1.7 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 KFM65027.1 - 1.6e-05 24.7 0.3 4.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term NleF_casp_inhib PF16809.5 KFM65027.1 - 0.042 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 NleF caspase inhibitor VF530 PF09905.9 KFM65030.1 - 0.13 12.4 0.7 0.59 10.3 0.2 1.9 1 1 1 2 2 2 0 DNA-binding protein VF530 RabGAP-TBC PF00566.18 KFM65031.1 - 8.9e-23 81.1 0.8 1.5e-22 80.3 0.8 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HTH_Tnp_Tc3_2 PF01498.18 KFM65033.1 - 2.3e-16 59.8 2.2 4.1e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65033.1 - 5.3e-12 45.7 0.0 8.7e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65034.1 - 4.3e-16 58.9 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65034.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65034.1 - 1.8e-07 30.8 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65034.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65034.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Transposase_1 PF01359.18 KFM65035.1 - 4.9e-13 48.7 0.2 1.6e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM65035.1 - 2.9e-08 33.6 0.0 5.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RFX_DNA_binding PF02257.15 KFM65036.1 - 3.1e-10 40.5 0.2 5.6e-10 39.7 0.2 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain DDE_3 PF13358.6 KFM65038.1 - 0.008 15.9 0.0 0.44 10.3 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease DUF1330 PF07045.11 KFM65039.1 - 0.011 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Arm PF00514.23 KFM65040.1 - 0.00028 20.8 2.9 0.11 12.5 0.1 3.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat PAT1 PF09770.9 KFM65041.1 - 5.6e-11 41.5 9.9 2.5e-09 36.0 0.1 3.9 4 0 0 4 4 4 3 Topoisomerase II-associated protein PAT1 Pih1_fungal_CS PF18482.1 KFM65042.1 - 0.077 13.5 0.4 10 6.7 0.1 2.3 2 0 0 2 2 2 0 Fungal Pih1 CS domain VPS13 PF16908.5 KFM65044.1 - 0.025 14.4 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KFM65045.1 - 4.8e-26 91.1 0.1 5.5e-26 91.0 0.1 1.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Sar8_2 PF03058.14 KFM65047.1 - 0.13 12.9 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Sar8.2 family DCX PF03607.17 KFM65048.1 - 7.1e-28 96.5 0.3 4.2e-17 62.0 0.0 2.7 2 0 0 2 2 2 2 Doublecortin Tugs PF17840.1 KFM65048.1 - 0.29 11.4 0.1 0.29 11.4 0.1 1.9 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain DDE_1 PF03184.19 KFM65049.1 - 1.5e-05 24.7 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Mpv17_PMP22 PF04117.12 KFM65049.1 - 8.9e-05 22.6 0.3 0.00051 20.2 0.3 2.3 1 1 0 1 1 1 1 Mpv17 / PMP22 family GTP_EFTU PF00009.27 KFM65050.1 - 1.6e-54 184.4 0.0 2.3e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFM65050.1 - 1.4e-42 144.6 0.1 3.4e-42 143.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFM65050.1 - 2.7e-14 53.3 0.6 2.7e-14 53.3 0.6 2.4 3 1 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM65050.1 - 0.00019 21.5 0.2 0.0054 16.8 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM65050.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU_D4 PF14578.6 KFM65050.1 - 0.017 15.0 1.7 0.023 14.6 0.2 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 KFM65050.1 - 0.14 12.2 0.1 17 5.4 0.1 2.6 2 0 0 2 2 2 0 Dynamin family TGF_beta PF00019.20 KFM65051.1 - 7.7e-23 81.4 1.8 1.1e-22 81.0 1.8 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain DUF3330 PF11809.8 KFM65051.1 - 0.041 13.9 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) DAN PF03045.15 KFM65051.1 - 0.22 11.6 2.6 0.47 10.5 2.6 1.6 1 1 0 1 1 1 0 DAN domain Integrase_H2C2 PF17921.1 KFM65052.1 - 1.8e-19 69.6 0.1 1.9e-19 69.5 0.1 1.0 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM65052.1 - 7.3e-06 26.1 0.4 9.2e-06 25.8 0.4 1.1 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 KFM65053.1 - 2.9e-11 43.3 0.2 4.2e-09 36.3 0.2 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTB PF00651.31 KFM65054.1 - 1.5e-33 115.3 1.6 1.7e-19 70.1 1.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB_3 PF16017.5 KFM65054.1 - 0.0013 18.8 0.1 0.15 12.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain NIF3 PF01784.18 KFM65055.1 - 1.5e-72 244.2 0.0 2e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Astacin PF01400.24 KFM65057.1 - 1.5e-46 158.4 1.0 1.8e-46 158.2 1.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM65057.1 - 0.00029 20.7 0.1 0.091 12.6 0.0 2.1 2 0 0 2 2 2 2 Matrixin Reprolysin_4 PF13583.6 KFM65057.1 - 0.072 12.7 0.1 0.091 12.4 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 KFM65057.1 - 0.17 11.4 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase PIF1 PF05970.14 KFM65059.1 - 1.3e-54 185.8 0.0 1.4e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFM65059.1 - 0.0052 16.5 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM65059.1 - 0.008 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF2791 PF10923.8 KFM65059.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ResIII PF04851.15 KFM65059.1 - 0.035 14.1 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CbiA PF01656.23 KFM65059.1 - 0.056 13.5 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 KFM65059.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ferlin_C PF16165.5 KFM65060.1 - 1.7e-36 125.5 3.2 2.8e-29 102.1 0.1 2.0 1 1 1 2 2 2 2 Ferlin C-terminus DUF3687 PF12459.8 KFM65060.1 - 0.089 12.3 2.4 0.15 11.6 2.4 1.4 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Wzz PF02706.15 KFM65060.1 - 0.47 10.8 3.2 0.71 10.2 3.2 1.3 1 0 0 1 1 1 0 Chain length determinant protein Synaptobrevin PF00957.21 KFM65060.1 - 1.8 8.4 4.3 2.7 7.9 4.3 1.2 1 0 0 1 1 1 0 Synaptobrevin C2 PF00168.30 KFM65061.1 - 0.0014 18.9 0.0 0.088 13.1 0.0 2.4 1 1 0 1 1 1 1 C2 domain PUF PF00806.19 KFM65062.1 - 1.3e-08 34.1 0.0 2.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat RNA_pol_Rpb2_1 PF04563.15 KFM65062.1 - 0.051 13.1 0.0 0.052 13.0 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase beta subunit BRCT_2 PF16589.5 KFM65063.1 - 3.7e-12 46.5 0.0 1.2e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF2850 PF11012.8 KFM65063.1 - 0.2 12.0 0.0 0.46 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) PAC4 PF16093.5 KFM65064.1 - 0.00065 19.8 0.0 0.00078 19.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 SPC22 PF04573.12 KFM65065.1 - 3.5e-05 23.4 0.3 3.5e-05 23.4 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Ribosomal_L16 PF00252.18 KFM65066.1 - 2.9e-25 88.8 0.0 4.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SpoU_methylase PF00588.19 KFM65067.1 - 6e-21 75.1 0.0 2.3e-18 66.7 0.0 2.3 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KFM65067.1 - 0.13 12.5 0.1 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding T-box PF00907.22 KFM65068.1 - 0.00029 21.1 0.2 0.00042 20.6 0.2 1.2 1 0 0 1 1 1 1 T-box Pkinase PF00069.25 KFM65069.1 - 4.8e-73 245.8 0.1 1e-72 244.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65069.1 - 1.4e-34 119.6 0.0 2.6e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM65069.1 - 1.7e-07 30.5 0.1 1.7e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KFM65069.1 - 0.00073 18.9 0.0 0.0073 15.7 0.0 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFM65069.1 - 0.07 13.0 0.0 10 5.9 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Imm7 PF15585.6 KFM65069.1 - 0.17 12.2 0.0 0.46 10.8 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 7 zf-C2H2 PF00096.26 KFM65070.1 - 5.7e-35 117.8 125.5 8.5e-06 25.9 1.4 14.1 14 0 0 14 14 14 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65070.1 - 8.6e-29 97.7 116.3 0.00035 21.2 0.7 13.9 14 0 0 14 14 14 11 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM65070.1 - 4.6e-16 58.4 99.9 8.2e-05 22.9 1.7 13.9 14 0 0 14 14 14 8 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM65070.1 - 1.8e-10 40.8 108.1 4.3e-06 26.9 0.8 13.5 13 0 0 13 13 13 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM65070.1 - 1.6e-09 37.8 97.9 0.00019 21.7 1.7 13.2 13 0 0 13 13 13 5 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM65070.1 - 0.00089 19.0 58.6 0.0097 15.7 2.2 9.9 9 0 0 9 9 9 4 zinc-finger C2H2-type BolA PF01722.18 KFM65070.1 - 0.0015 18.7 19.4 1.7 9.0 0.0 6.8 5 1 3 8 8 8 2 BolA-like protein zf-C2H2_6 PF13912.6 KFM65070.1 - 0.024 14.6 1.6 0.024 14.6 1.6 12.1 12 0 0 12 12 12 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM65070.1 - 0.068 13.1 0.2 0.068 13.1 0.2 10.5 12 0 0 12 12 12 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KFM65070.1 - 0.41 11.0 78.6 0.14 12.5 2.8 7.8 6 1 1 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding HTH_Tnp_Tc3_2 PF01498.18 KFM65072.1 - 5.2e-16 58.7 3.5 6.2e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65072.1 - 7.4e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65072.1 - 2.3e-07 30.4 1.2 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65072.1 - 0.003 17.3 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65072.1 - 2.8 8.6 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM65073.1 - 0.00053 19.4 0.3 0.00077 18.9 0.3 1.2 1 0 0 1 1 1 1 Transposase IS4 Pex14_N PF04695.13 KFM65073.1 - 0.0074 17.0 0.5 0.014 16.0 0.5 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TIG_2 PF18020.1 KFM65073.1 - 0.13 12.9 0.3 0.3 11.7 0.1 1.6 2 0 0 2 2 2 0 TIG domain found in plexin Rad50_zn_hook PF04423.14 KFM65073.1 - 0.14 12.0 5.6 4.5 7.2 0.8 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif SNAP PF14938.6 KFM65074.1 - 1.2e-34 120.1 4.5 1.7e-34 119.6 4.5 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KFM65074.1 - 0.00015 22.0 1.9 0.026 14.8 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat DDE_3 PF13358.6 KFM65074.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease FhuF PF06276.12 KFM65074.1 - 0.0038 17.6 0.0 0.0063 16.9 0.0 1.3 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Sel1 PF08238.12 KFM65074.1 - 0.0053 17.4 0.1 1.8 9.4 0.1 2.7 3 0 0 3 3 3 1 Sel1 repeat TPR_8 PF13181.6 KFM65074.1 - 0.0087 16.2 1.5 4.9 7.6 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM65074.1 - 0.011 15.7 2.2 2.8 8.3 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM65074.1 - 0.028 14.2 3.1 1.3 9.0 0.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DHR-2 PF06920.13 KFM65074.1 - 0.062 11.9 1.5 0.12 11.0 1.1 1.5 1 1 0 1 1 1 0 Dock homology region 2 HTH_Tnp_Tc3_2 PF01498.18 KFM65075.1 - 1.5e-10 41.1 5.5 4.4e-10 39.7 5.5 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65075.1 - 2.2e-10 40.4 0.0 2.5e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_12 PF08461.10 KFM65075.1 - 0.0093 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Bac_DnaA_C PF08299.11 KFM65075.1 - 0.024 14.7 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix zf-H2C2_2 PF13465.6 KFM65076.1 - 3.5e-46 153.7 49.8 2.4e-09 37.2 1.2 7.2 7 0 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65076.1 - 1.5e-27 94.5 61.8 4.7e-05 23.6 2.9 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65076.1 - 1e-23 81.9 57.1 0.00071 20.2 2.0 6.4 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFM65076.1 - 3.1e-16 59.1 49.9 0.0074 16.6 2.2 6.7 6 1 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65076.1 - 7.6e-14 51.6 40.2 0.0027 17.9 0.5 7.1 5 2 2 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM65076.1 - 2.2e-09 36.9 37.9 0.057 13.2 0.8 7.0 7 0 0 7 7 6 5 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM65076.1 - 3.5e-09 36.4 47.8 0.042 13.9 1.2 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM65076.1 - 2.8e-06 27.0 24.6 0.27 11.1 0.2 6.0 1 1 5 6 6 6 4 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFM65076.1 - 3.9e-05 23.7 23.3 0.83 9.8 3.2 6.2 6 0 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM65076.1 - 0.00013 22.0 28.9 1.1 9.5 0.2 6.4 6 1 0 6 6 6 5 DBF zinc finger zf-C2H2_2 PF12756.7 KFM65076.1 - 0.0014 18.9 45.3 0.37 11.1 0.9 6.1 1 1 5 6 6 6 3 C2H2 type zinc-finger (2 copies) Tox-HNH-HHH PF15637.6 KFM65076.1 - 0.0022 18.1 0.5 6.3 7.0 0.1 3.0 1 1 2 3 3 3 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif GAGA PF09237.11 KFM65076.1 - 0.0023 17.7 23.8 0.03 14.1 0.1 4.9 1 1 3 5 5 5 2 GAGA factor zf-RRPl_C4 PF17026.5 KFM65076.1 - 0.0091 16.1 26.2 0.21 11.7 12.3 3.3 1 1 2 3 3 3 1 Putative ribonucleoprotein zinc-finger pf C4 type ADK_lid PF05191.14 KFM65076.1 - 0.026 14.5 22.5 0.048 13.6 2.0 4.3 2 1 1 4 4 4 0 Adenylate kinase, active site lid zf-CHCC PF10276.9 KFM65076.1 - 0.039 14.0 8.2 35 4.5 0.0 5.8 6 0 0 6 6 6 0 Zinc-finger domain TRAF6_Z2 PF18048.1 KFM65076.1 - 0.063 13.4 0.7 0.063 13.4 0.7 5.9 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 C1_1 PF00130.22 KFM65076.1 - 0.065 13.1 34.8 6.6 6.7 0.3 6.1 1 1 3 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HIT PF04438.16 KFM65076.1 - 0.071 13.0 30.0 5 7.1 0.7 6.3 6 0 0 6 6 6 0 HIT zinc finger zinc_ribbon_15 PF17032.5 KFM65076.1 - 0.086 13.6 24.8 1.4 9.7 1.5 3.3 1 1 2 3 3 3 0 zinc-ribbon family BolA PF01722.18 KFM65076.1 - 0.11 12.8 11.8 1.4 9.3 0.5 4.0 1 1 3 4 4 4 0 BolA-like protein zf-MYST PF17772.1 KFM65076.1 - 0.24 11.0 29.7 8.1 6.1 0.3 6.1 4 2 2 6 6 6 0 MYST family zinc finger domain zf-FPG_IleRS PF06827.14 KFM65076.1 - 0.51 10.2 25.8 18 5.3 0.1 6.3 6 0 0 6 6 6 0 Zinc finger found in FPG and IleRS FYVE PF01363.21 KFM65076.1 - 0.74 10.0 36.3 31 4.8 24.5 3.4 1 1 1 2 2 2 0 FYVE zinc finger zf-H2C2_2 PF13465.6 KFM65077.1 - 4.6e-67 219.7 89.1 1e-09 38.4 3.3 13.9 14 0 0 14 14 14 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65077.1 - 1.6e-58 192.0 109.0 1.5e-06 28.3 0.3 13.8 13 1 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65077.1 - 1.6e-48 159.1 97.3 0.00014 22.4 2.2 13.1 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM65077.1 - 8e-34 115.0 91.1 0.0012 19.2 2.2 13.4 14 0 0 14 14 13 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65077.1 - 1.1e-30 105.3 81.3 0.00047 20.4 0.0 13.2 13 1 0 13 13 13 12 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM65077.1 - 2.5e-27 94.3 82.4 0.004 17.1 0.2 13.9 13 1 0 13 13 13 10 C2H2-type zinc finger BolA PF01722.18 KFM65077.1 - 1.8e-05 25.0 15.3 6.7 7.1 0.0 7.2 3 2 2 5 5 5 1 BolA-like protein zf-C2HC_2 PF13913.6 KFM65077.1 - 9.4e-05 22.2 52.9 0.43 10.5 0.4 12.4 13 0 0 13 13 13 2 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM65077.1 - 0.0049 16.8 3.1 0.0049 16.8 3.1 8.2 5 3 2 7 7 7 2 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM65077.1 - 0.0069 16.0 54.6 1.7 8.3 0.1 11.4 7 3 5 12 12 12 4 MYST family zinc finger domain zf-H2C2_5 PF13909.6 KFM65077.1 - 0.024 14.4 0.1 0.024 14.4 0.1 11.0 13 0 0 13 13 13 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 KFM65077.1 - 0.073 13.8 55.8 0.99 10.2 9.5 6.3 2 1 6 8 8 8 0 zinc-ribbon family DUF3850 PF12961.7 KFM65077.1 - 0.078 13.0 0.0 2.4 8.3 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3850) zf_UBZ PF18439.1 KFM65077.1 - 0.21 11.2 63.1 1.1 8.9 0.3 12.8 13 0 0 13 13 13 0 Ubiquitin-Binding Zinc Finger DUF3268 PF11672.8 KFM65077.1 - 0.23 11.8 0.2 0.23 11.8 0.2 6.6 4 1 3 8 8 8 0 zinc-finger-containing domain Zf_RING PF16744.5 KFM65077.1 - 0.62 10.2 61.3 2.5 8.3 1.5 10.6 1 1 8 9 9 9 0 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KFM65077.1 - 2.4 8.5 77.8 6.7 7.1 0.9 12.2 1 1 11 12 12 12 0 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 KFM65077.1 - 3.3 8.2 51.4 11 6.6 0.1 12.0 12 0 0 12 12 12 0 Autophagy receptor zinc finger-C2H2 domain FYVE PF01363.21 KFM65077.1 - 5.1 7.3 70.2 5.4 7.2 10.9 7.7 3 2 2 5 5 4 0 FYVE zinc finger zf-H2C2_2 PF13465.6 KFM65079.1 - 6.2e-75 244.5 90.3 2.9e-09 36.9 1.8 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65079.1 - 8.3e-49 161.4 118.1 6e-06 26.4 1.2 11.4 12 0 0 12 12 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65079.1 - 7e-39 129.1 103.8 0.00098 19.8 1.9 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65079.1 - 3.4e-22 77.9 78.2 0.00096 19.1 0.4 11.5 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM65079.1 - 6e-21 74.1 89.1 0.00064 20.0 0.6 12.0 11 1 1 12 12 12 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65079.1 - 1.3e-15 57.2 72.2 0.0071 16.6 0.4 11.8 10 1 1 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM65079.1 - 3.1e-10 39.6 75.3 0.12 12.2 0.9 11.4 11 0 0 11 11 11 8 C2H2-type zinc-finger domain GAGA PF09237.11 KFM65079.1 - 3e-06 26.9 33.7 0.076 12.8 0.0 8.8 2 2 8 10 10 10 3 GAGA factor BolA PF01722.18 KFM65079.1 - 0.0004 20.6 19.9 0.11 12.8 0.1 6.0 1 1 4 6 6 6 2 BolA-like protein zf-RRPl_C4 PF17026.5 KFM65079.1 - 0.0019 18.3 50.6 0.073 13.2 5.8 5.0 1 1 5 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFM65079.1 - 0.0023 18.6 48.7 0.4 11.5 3.0 5.8 2 1 3 5 5 5 3 zinc-ribbon family zf-CHCC PF10276.9 KFM65079.1 - 0.0039 17.2 16.0 10 6.3 0.0 9.0 11 0 0 11 11 11 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KFM65079.1 - 0.0055 16.6 50.3 3.9 7.5 0.2 10.9 11 0 0 11 11 11 2 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM65079.1 - 0.0056 16.6 45.3 0.084 12.9 3.3 6.6 4 1 3 7 7 7 2 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM65079.1 - 0.011 15.9 42.3 24 5.2 0.4 10.7 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 KFM65079.1 - 0.028 14.3 53.6 0.38 10.6 0.3 10.7 4 2 7 11 11 11 0 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM65079.1 - 0.29 11.2 47.0 2.1 8.5 0.6 10.0 7 4 4 11 11 11 0 Sec23/Sec24 zinc finger FYVE PF01363.21 KFM65079.1 - 0.68 10.1 63.1 2.9 8.1 15.1 5.5 1 1 2 3 3 2 0 FYVE zinc finger zf-MYST PF17772.1 KFM65079.1 - 0.86 9.3 57.4 0.6 9.8 0.7 10.6 7 3 4 11 11 11 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 KFM65080.1 - 2.7e-50 166.7 51.2 1.5e-07 31.5 0.5 8.1 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65080.1 - 1.2e-34 116.8 60.8 5.4e-06 26.6 1.8 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65080.1 - 3.2e-28 96.0 57.0 0.00037 21.1 0.9 7.2 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 KFM65080.1 - 3.1e-17 62.3 47.5 0.0024 18.2 0.9 7.4 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65080.1 - 2.1e-14 53.4 37.2 0.0049 17.1 1.1 7.4 6 1 1 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM65080.1 - 5.6e-12 45.3 47.8 0.028 14.4 1.5 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM65080.1 - 7e-10 38.5 38.3 0.043 13.6 0.5 7.4 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM65080.1 - 6.8e-07 29.0 29.3 0.14 12.1 0.2 7.0 7 0 0 7 7 7 4 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM65080.1 - 1.2e-05 25.4 19.9 3.7 7.7 0.0 7.0 7 0 0 7 7 7 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 KFM65080.1 - 7.3e-05 22.5 26.5 0.55 10.1 0.3 6.6 4 2 3 7 7 7 3 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM65080.1 - 0.00012 22.1 27.2 8.6 6.6 0.2 7.0 6 1 0 6 6 6 0 DBF zinc finger BolA PF01722.18 KFM65080.1 - 0.00058 20.1 11.1 2.6 8.4 0.3 4.8 1 1 2 4 4 4 2 BolA-like protein zf-C2H2_2 PF12756.7 KFM65080.1 - 0.00064 20.0 42.0 0.87 10.0 1.7 6.7 1 1 6 7 7 7 3 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM65080.1 - 0.00095 19.1 17.4 1.5 8.8 1.5 4.9 1 1 4 5 5 5 1 Adenylate kinase, active site lid zf-RRPl_C4 PF17026.5 KFM65080.1 - 0.0018 18.4 19.7 0.055 13.6 5.4 3.4 1 1 1 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type DZR PF12773.7 KFM65080.1 - 0.0039 17.2 18.2 1.8e+04 -4.4 18.2 4.2 1 1 0 1 1 0 0 Double zinc ribbon zf-MYST PF17772.1 KFM65080.1 - 0.006 16.2 26.7 12 5.6 1.5 7.0 5 2 2 7 7 7 0 MYST family zinc finger domain zf-CHCC PF10276.9 KFM65080.1 - 0.0067 16.5 6.8 41 4.3 0.0 6.3 7 0 0 7 7 7 0 Zinc-finger domain GAGA PF09237.11 KFM65080.1 - 0.0092 15.8 18.6 0.27 11.1 0.5 6.0 1 1 6 7 7 7 2 GAGA factor zf-HIT PF04438.16 KFM65080.1 - 0.012 15.5 32.1 4.3 7.3 0.3 7.1 7 0 0 7 7 7 0 HIT zinc finger Prok-RING_1 PF14446.6 KFM65080.1 - 0.014 15.3 22.8 6.3 6.8 0.1 6.9 7 0 0 7 7 7 0 Prokaryotic RING finger family 1 FYVE PF01363.21 KFM65080.1 - 0.017 15.2 30.0 0.11 12.6 6.4 4.1 1 1 2 3 3 3 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KFM65080.1 - 0.041 13.6 0.1 0.041 13.6 0.1 6.4 6 0 0 6 6 6 0 zinc-finger C2H2-type DUF2039 PF10217.9 KFM65080.1 - 0.047 14.0 18.0 0.41 11.0 3.7 3.4 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2039) PqqA PF08042.11 KFM65080.1 - 0.069 13.2 0.7 2.5e+02 1.9 0.0 4.8 5 0 0 5 5 5 0 PqqA family zf_UBZ PF18439.1 KFM65080.1 - 0.12 12.0 28.9 8.2 6.1 0.3 7.1 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KFM65080.1 - 0.35 11.7 22.2 1.7e+02 3.1 8.7 4.0 1 1 1 2 2 2 0 zinc-ribbon family zf-FCS PF06467.14 KFM65080.1 - 0.43 10.6 22.5 9.5 6.3 0.1 6.7 7 0 0 7 7 7 0 MYM-type Zinc finger with FCS sequence motif VGCC_alpha2 PF08473.11 KFM65080.1 - 0.89 8.3 5.8 4 6.1 0.6 2.4 2 1 1 3 3 3 0 Neuronal voltage-dependent calcium channel alpha 2acd DUF4764 PF15961.5 KFM65080.1 - 4 6.0 16.0 1.3 7.6 0.2 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4764) zf-FPG_IleRS PF06827.14 KFM65080.1 - 8.7 6.3 25.9 1.6 8.6 0.1 6.6 7 0 0 7 7 7 0 Zinc finger found in FPG and IleRS zf-U1 PF06220.12 KFM65081.1 - 1.7e-09 37.2 0.3 3e-09 36.5 0.3 1.4 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.26 KFM65081.1 - 6.8e-06 26.1 4.3 1.5e-05 24.9 4.3 1.6 1 0 0 1 1 1 1 WW domain KH_5 PF13184.6 KFM65081.1 - 0.099 12.7 0.3 0.3 11.2 0.2 1.8 2 0 0 2 2 2 0 NusA-like KH domain zf-C2H2_jaz PF12171.8 KFM65081.1 - 0.47 10.8 6.9 2.6 8.5 6.9 2.3 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding L31 PF09784.9 KFM65081.1 - 0.87 10.0 6.8 3.5 8.1 5.8 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 Ribosomal_S8 PF00410.19 KFM65081.1 - 3.7 7.5 5.8 3.4 7.6 0.6 2.5 1 1 1 2 2 2 0 Ribosomal protein S8 Ins145_P3_rec PF08709.11 KFM65082.1 - 1.3e-64 217.4 0.3 4.2e-64 215.6 0.1 1.9 2 1 1 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 KFM65082.1 - 1.7e-59 200.7 0.4 4.7e-59 199.2 0.6 1.7 2 0 0 2 2 2 1 RIH domain MIR PF02815.19 KFM65082.1 - 1.1e-50 172.0 0.0 5.9e-45 153.4 0.0 2.3 2 0 0 2 2 2 2 MIR domain RyR PF02026.16 KFM65082.1 - 3.1e-23 81.8 0.0 6.6e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 RyR domain SPRY PF00622.28 KFM65082.1 - 9.6e-20 70.9 0.2 2.1e-19 69.8 0.2 1.6 1 0 0 1 1 1 1 SPRY domain RYDR_ITPR PF01365.21 KFM65083.1 - 2.1e-72 242.8 0.0 4.4e-72 241.8 0.0 1.6 1 0 0 1 1 1 1 RIH domain SPRY PF00622.28 KFM65083.1 - 1.7e-41 141.1 3.1 1.8e-21 76.4 0.1 2.5 2 0 0 2 2 2 2 SPRY domain RyR PF02026.16 KFM65083.1 - 4.3e-30 103.7 0.1 9.3e-30 102.7 0.1 1.6 1 0 0 1 1 1 1 RyR domain Ion_trans PF00520.31 KFM65084.1 - 4e-10 39.3 0.6 4.4e-10 39.2 0.6 1.0 1 0 0 1 1 1 1 Ion transport protein Serinc PF03348.15 KFM65084.1 - 0.049 12.6 1.1 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) HTH_Tnp_Tc3_2 PF01498.18 KFM65085.1 - 2.2e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65085.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease FARP PF01581.16 KFM65086.1 - 6.9e-34 109.7 0.0 1.5e+02 3.6 0.1 33.4 40 0 0 40 40 40 0 FMRFamide related peptide family DUF2550 PF10739.9 KFM65086.1 - 0.0053 16.8 0.7 3.9 7.5 0.0 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF2550) PTSIIA_gutA PF03829.13 KFM65086.1 - 0.14 12.1 0.0 1.6 8.6 0.0 3.1 1 0 0 1 1 1 0 PTS system glucitol/sorbitol-specific IIA component RabGAP-TBC PF00566.18 KFM65087.1 - 4.3e-20 72.3 5.2 5.6e-20 71.9 5.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KFM65088.1 - 0.00016 21.2 0.0 0.00037 20.0 0.0 1.7 1 0 0 1 1 1 1 Rab-binding domain (RBD) zf-H2C2_2 PF13465.6 KFM65089.1 - 5.6e-125 402.7 129.2 3.8e-08 33.4 0.9 20.1 20 0 0 20 20 20 19 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65089.1 - 1.7e-98 317.9 163.9 5.4e-06 26.6 0.5 19.9 20 0 0 20 20 20 19 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65089.1 - 3.3e-64 207.9 149.3 4.7e-05 23.9 0.4 20.0 20 0 0 20 20 20 19 C2H2-type zinc finger zf-met PF12874.7 KFM65089.1 - 1.7e-40 136.2 131.1 0.003 17.9 2.3 19.5 19 0 0 19 19 19 16 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65089.1 - 6e-39 131.4 117.6 0.0023 17.9 2.0 19.7 19 0 0 19 19 19 18 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65089.1 - 9.6e-20 70.4 110.4 0.02 15.2 0.2 19.2 19 0 0 19 19 19 12 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM65089.1 - 1.2e-09 37.7 125.9 0.048 13.4 0.6 19.0 20 0 0 20 20 18 10 C2H2-type zinc-finger domain GAGA PF09237.11 KFM65089.1 - 7.1e-09 35.3 56.3 0.084 12.7 0.3 13.7 3 3 12 16 16 16 5 GAGA factor zinc_ribbon_15 PF17032.5 KFM65089.1 - 0.00026 21.7 81.4 1.7 9.5 1.9 9.9 1 1 13 14 14 14 8 zinc-ribbon family Baculo_IE-1 PF05290.11 KFM65089.1 - 0.0015 18.5 67.0 3.7 7.5 3.3 12.3 1 1 7 9 9 9 2 Baculovirus immediate-early protein (IE-0) zf-BED PF02892.15 KFM65089.1 - 0.0049 16.9 145.6 0.05 13.6 3.4 18.1 2 2 17 19 19 19 5 BED zinc finger zf-MYST PF17772.1 KFM65089.1 - 0.0053 16.3 94.7 0.4 10.3 0.2 17.7 6 4 13 19 19 19 5 MYST family zinc finger domain Glyco_hydro_98C PF08307.11 KFM65089.1 - 0.048 13.1 0.1 0.26 10.8 0.0 2.3 2 0 0 2 2 1 0 Glycosyl hydrolase family 98 C-terminal domain zf_C2H2_ZHX PF18387.1 KFM65089.1 - 0.063 12.9 0.3 0.063 12.9 0.3 11.3 7 4 7 14 14 14 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HC_2 PF13913.6 KFM65089.1 - 0.079 12.9 0.2 0.079 12.9 0.2 14.9 18 0 0 18 18 16 0 zinc-finger of a C2HC-type FAS_meander PF17951.1 KFM65089.1 - 0.1 12.4 0.1 8.7 6.1 0.0 3.2 3 0 0 3 3 3 0 Fatty acid synthase meander beta sheet domain zf-C2H2_2 PF12756.7 KFM65089.1 - 0.31 11.4 126.1 3.2 8.1 0.4 14.8 1 1 9 12 12 11 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM65089.1 - 0.51 10.4 74.6 1 9.4 1.3 12.7 6 5 7 13 13 13 0 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM65089.1 - 0.6 10.3 78.3 3.2 8.0 0.3 17.4 18 1 1 19 19 19 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.6 KFM65091.1 - 1.8e-59 195.6 81.2 1.1e-08 35.1 1.5 10.4 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65091.1 - 2.9e-42 140.8 94.5 2.9e-05 24.3 3.3 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65091.1 - 5.4e-34 113.9 85.2 0.00056 20.5 1.0 10.1 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFM65091.1 - 2.9e-21 75.1 81.3 0.00041 20.6 1.0 10.2 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65091.1 - 4.8e-17 61.8 57.2 0.00082 19.6 0.4 9.6 9 0 0 9 9 9 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM65091.1 - 5.3e-09 35.9 77.5 0.0029 17.5 0.8 10.4 11 0 0 11 11 9 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM65091.1 - 2.7e-07 30.2 56.4 0.068 12.9 0.2 9.7 10 0 0 10 10 10 5 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM65091.1 - 1.6e-06 27.8 55.6 0.015 15.1 1.3 8.8 10 0 0 10 10 10 5 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM65091.1 - 3e-06 27.2 35.9 1.5 9.0 0.1 8.3 5 3 3 8 8 8 4 Sec23/Sec24 zinc finger Tox-HNH-HHH PF15637.6 KFM65091.1 - 3.6e-05 23.8 0.7 5.6 7.2 0.0 4.0 2 1 2 4 4 4 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif BolA PF01722.18 KFM65091.1 - 0.00031 20.9 12.0 1.7 9.0 0.3 5.9 1 1 6 7 7 7 1 BolA-like protein GAGA PF09237.11 KFM65091.1 - 0.00099 18.9 19.5 3.2 7.6 0.1 6.5 1 1 8 9 9 9 2 GAGA factor Zf_RING PF16744.5 KFM65091.1 - 0.016 15.3 45.8 0.63 10.2 1.6 8.1 1 1 4 6 6 6 0 KIAA1045 RING finger zf-DBF PF07535.12 KFM65091.1 - 0.028 14.5 48.4 4.3 7.5 0.1 8.7 9 0 0 9 9 9 0 DBF zinc finger Zn-C2H2_12 PF18112.1 KFM65091.1 - 0.077 13.5 49.1 3.1 8.3 1.2 9.5 9 0 0 9 9 9 0 Autophagy receptor zinc finger-C2H2 domain zf-RRPl_C4 PF17026.5 KFM65091.1 - 0.11 12.6 48.4 0.3 11.2 9.2 4.3 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_9 PF16293.5 KFM65091.1 - 0.12 12.3 47.7 0.96 9.3 0.1 9.5 1 1 9 10 10 10 0 C2H2 type zinc-finger (1 copy) DUF3541 PF12060.8 KFM65091.1 - 0.15 11.7 0.2 0.99 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) DUF5330 PF17264.2 KFM65091.1 - 0.38 10.8 22.3 73 3.5 0.1 7.5 7 1 1 8 8 8 0 Family of unknown function (DUF5330) A_deaminase PF00962.22 KFM65091.1 - 0.48 9.7 13.5 1.1 8.6 0.5 3.8 1 1 4 5 5 5 0 Adenosine/AMP deaminase zf-C2HC_2 PF13913.6 KFM65091.1 - 1.7 8.6 48.9 0.51 10.3 0.4 10.0 9 1 1 10 10 10 0 zinc-finger of a C2HC-type Amidohydro_1 PF01979.20 KFM65091.1 - 2.1 7.6 16.7 8.7 5.5 1.4 4.8 1 1 4 5 5 5 0 Amidohydrolase family C1_1 PF00130.22 KFM65091.1 - 9.2 6.3 57.8 9.3 6.2 5.7 7.8 2 2 4 6 6 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFM65091.1 - 9.6 7.0 47.5 1.3 9.8 3.1 5.3 1 1 2 5 5 5 0 zinc-ribbon family zf-H2C2_2 PF13465.6 KFM65092.1 - 2.9e-79 258.2 75.4 4.6e-09 36.3 1.3 11.1 11 0 0 11 11 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65092.1 - 6.4e-45 149.2 92.4 3.1e-06 27.3 2.7 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65092.1 - 4e-35 117.4 79.2 0.00055 20.6 0.7 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM65092.1 - 2.9e-33 113.3 91.1 0.00021 21.5 1.2 10.3 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65092.1 - 6.5e-22 77.3 58.6 0.0055 17.0 2.3 10.3 10 0 0 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM65092.1 - 2.3e-15 56.0 47.7 0.0058 16.4 0.4 10.5 10 0 0 10 10 10 6 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM65092.1 - 1.3e-13 50.7 45.0 0.12 12.5 0.3 10.6 4 3 7 11 11 11 6 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 KFM65092.1 - 3.8e-13 49.1 67.7 0.0034 17.3 1.4 10.6 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM65092.1 - 4.1e-09 36.0 58.9 0.00089 19.0 0.4 10.1 10 0 0 10 10 10 4 zinc-finger C2H2-type BolA PF01722.18 KFM65092.1 - 8.3e-09 35.6 11.6 0.5 10.7 0.9 7.7 1 1 6 7 7 7 3 BolA-like protein zf-C2HC_2 PF13913.6 KFM65092.1 - 7.2e-08 32.1 44.2 0.28 11.2 0.1 9.8 10 0 0 10 10 10 6 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM65092.1 - 1.4e-06 28.3 50.5 1.7 8.8 0.8 10.3 10 0 0 10 10 10 2 DBF zinc finger Zf_RING PF16744.5 KFM65092.1 - 0.00039 20.5 50.4 0.46 10.6 1.3 9.8 1 1 6 8 8 8 1 KIAA1045 RING finger Yop-YscD_ppl PF16693.5 KFM65092.1 - 0.00069 19.1 0.0 0.22 10.9 0.0 3.3 1 1 3 4 4 4 1 Inner membrane component of T3SS, periplasmic domain zinc_ribbon_15 PF17032.5 KFM65092.1 - 0.0018 19.0 49.0 0.22 12.3 3.5 5.1 1 1 4 5 5 5 4 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM65092.1 - 0.01 15.9 51.4 0.12 12.4 8.7 4.8 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-MYST PF17772.1 KFM65092.1 - 0.011 15.4 54.8 0.079 12.6 0.4 9.9 4 2 6 10 10 10 0 MYST family zinc finger domain DUF2256 PF10013.9 KFM65092.1 - 0.016 15.3 41.7 4.5 7.5 0.1 10.3 10 1 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KFM65092.1 - 0.061 13.7 78.1 1.7 9.0 1.2 9.9 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM65092.1 - 0.073 12.9 55.5 2.3 8.1 1.1 9.8 2 1 8 10 10 10 0 C2H2 type zinc-finger (1 copy) NAD_kinase PF01513.21 KFM65092.1 - 0.14 11.4 1.4 14 4.8 1.4 3.4 1 1 0 1 1 1 0 ATP-NAD kinase GAGA PF09237.11 KFM65092.1 - 0.2 11.5 24.0 1.9 8.4 0.0 7.0 1 1 8 9 9 9 0 GAGA factor TF_AP-2 PF03299.14 KFM65092.1 - 0.36 10.8 7.9 4.9 7.1 0.1 3.0 2 1 2 4 4 4 0 Transcription factor AP-2 C1_1 PF00130.22 KFM65092.1 - 0.62 10.0 55.3 0.4 10.6 2.1 8.6 1 1 6 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_SprT PF17283.2 KFM65092.1 - 1.1 9.2 31.8 2.3 8.2 0.4 7.3 5 3 2 7 7 7 0 SprT-like zinc ribbon domain MA3 PF02847.17 KFM65092.1 - 8 6.5 13.5 30 4.7 0.2 5.0 2 2 2 5 5 5 0 MA3 domain Prokineticin PF06607.11 KFM65093.1 - 0.00037 20.7 7.6 0.00046 20.5 7.6 1.2 1 0 0 1 1 1 1 Prokineticin RELT PF12606.8 KFM65093.1 - 0.69 8.9 4.3 6.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Nodulin_late PF07127.11 KFM65094.1 - 0.018 15.4 3.9 0.018 15.4 3.9 2.2 2 0 0 2 2 2 0 Late nodulin protein DUF2149 PF09919.9 KFM65094.1 - 0.081 13.2 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) CSN8_PSD8_EIF3K PF10075.9 KFM65095.1 - 0.073 13.0 0.0 0.075 13.0 0.0 1.1 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family RNA_pol_Rpa2_4 PF06883.12 KFM65096.1 - 9.9e-15 54.3 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_4 PF04566.13 KFM65096.1 - 0.017 15.4 1.4 0.49 10.7 1.4 2.2 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_6 PF00562.28 KFM65097.1 - 8.1e-79 265.5 0.0 2.4e-78 263.9 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 KFM65097.1 - 2.1e-16 60.1 1.3 2.8e-16 59.7 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 DUF4659 PF15558.6 KFM65098.1 - 4.8e-06 25.7 6.8 4.8e-06 25.7 6.8 1.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4659) DUF4659 PF15558.6 KFM65099.1 - 0.0096 14.8 14.9 0.01 14.7 14.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4659) DXP_reductoisom PF02670.16 KFM65099.1 - 0.0097 16.6 1.1 0.011 16.5 1.1 1.1 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF4659 PF15558.6 KFM65101.1 - 0.00012 21.1 7.9 0.00012 21.1 7.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4659) Cys_box PF17869.1 KFM65101.1 - 0.063 13.4 1.4 0.14 12.3 1.4 1.5 1 0 0 1 1 1 0 Anosmin cysteine rich domain RuvC_1 PF18516.1 KFM65101.1 - 0.36 10.0 2.7 0.56 9.4 2.7 1.2 1 0 0 1 1 1 0 RuvC nuclease domain APP_N PF02177.16 KFM65102.1 - 0.65 10.4 4.8 0.44 10.9 1.2 2.4 2 1 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding RF-1 PF00472.20 KFM65103.1 - 2.2e-19 69.5 0.3 3.9e-19 68.7 0.3 1.4 1 0 0 1 1 1 1 RF-1 domain Dimer_Tnp_hAT PF05699.14 KFM65103.1 - 0.00082 19.1 0.1 0.0019 17.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ADH_zinc_N PF00107.26 KFM65104.1 - 4.6e-16 59.0 0.0 7.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM65104.1 - 1.4e-14 55.3 0.0 2.6e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM65104.1 - 2.4e-12 46.7 0.1 7.2e-12 45.2 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 KFM65104.1 - 0.092 12.9 1.0 0.67 10.2 0.2 2.5 2 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DDE_3 PF13358.6 KFM65106.1 - 2.3e-14 53.3 0.1 6.5e-14 51.9 0.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65106.1 - 1.3e-10 41.3 1.0 2.7e-10 40.3 1.0 1.6 1 0 0 1 1 1 1 Transposase Choline_kinase PF01633.20 KFM65107.1 - 1.3e-58 198.1 0.0 1.9e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFM65107.1 - 2.5e-12 47.2 0.0 3.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFM65107.1 - 0.00038 19.9 0.0 0.00092 18.6 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KFM65108.1 - 5.2e-59 199.4 0.1 7.5e-59 198.9 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFM65108.1 - 6.6e-14 52.4 0.0 1.5e-13 51.2 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFM65108.1 - 0.00072 19.0 0.1 0.0027 17.1 0.1 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 KFM65108.1 - 0.015 14.6 0.1 0.099 12.0 0.0 2.1 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tup_N PF08581.10 KFM65108.1 - 0.029 14.7 3.3 5.9 7.3 0.8 2.9 3 0 0 3 3 3 0 Tup N-terminal Enkurin PF13864.6 KFM65110.1 - 3.2e-06 27.5 2.0 4.3e-06 27.1 2.0 1.2 1 0 0 1 1 1 1 Calmodulin-binding DDE_1 PF03184.19 KFM65111.1 - 2.1e-05 24.3 0.0 2.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM65111.1 - 0.0095 15.7 0.1 0.014 15.1 0.1 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease PDEase_I PF00233.19 KFM65114.1 - 6.4e-21 75.2 1.4 6.8e-21 75.1 1.4 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KFM65114.1 - 0.056 13.7 0.0 0.056 13.7 0.0 1.0 1 0 0 1 1 1 0 HD domain zf-H2C2_2 PF13465.6 KFM65115.1 - 2e-67 220.8 90.2 1.7e-10 40.9 0.2 12.1 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65115.1 - 1.2e-44 148.3 103.3 2.2e-06 27.8 1.9 11.2 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65115.1 - 1.2e-31 106.7 94.1 0.0003 21.4 1.2 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM65115.1 - 4.3e-24 84.1 75.6 0.0024 18.2 0.7 11.4 11 0 0 11 11 11 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65115.1 - 5.2e-18 64.6 71.2 0.01 15.8 0.3 11.4 11 0 0 11 11 11 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65115.1 - 1.6e-14 53.7 65.4 0.046 14.0 0.2 11.4 10 1 1 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM65115.1 - 1.1e-09 37.8 55.4 0.0097 15.7 1.0 10.7 10 0 0 10 10 10 5 C2H2-type zinc-finger domain BolA PF01722.18 KFM65115.1 - 1.2e-09 38.2 10.0 0.11 12.8 0.5 7.2 1 1 6 7 7 7 2 BolA-like protein GAGA PF09237.11 KFM65115.1 - 9.3e-05 22.2 41.0 0.4 10.5 0.1 9.3 1 1 9 11 11 11 4 GAGA factor C1_1 PF00130.22 KFM65115.1 - 0.00044 20.1 63.6 0.18 11.7 2.1 9.1 4 2 4 8 8 8 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Sec23_Sec24 PF04810.15 KFM65115.1 - 0.0017 18.4 48.4 2.6 8.2 0.0 10.6 7 3 3 10 10 10 1 Sec23/Sec24 zinc finger Peptidase_M15_2 PF05951.13 KFM65115.1 - 0.0046 16.6 0.5 1.9 8.1 0.0 3.9 2 2 2 4 4 4 1 Bacterial protein of unknown function (DUF882) ADK_lid PF05191.14 KFM65115.1 - 0.03 14.3 39.5 0.38 10.8 2.0 7.1 5 2 2 7 7 7 0 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM65115.1 - 0.09 12.7 0.2 0.09 12.7 0.2 9.7 11 0 0 11 11 10 0 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM65115.1 - 1.5 9.0 42.2 2.7 8.2 0.3 8.9 10 0 0 10 10 10 0 DBF zinc finger zf-C2H2_9 PF16293.5 KFM65115.1 - 1.7 8.5 47.5 14 5.6 0.2 10.4 2 2 9 11 11 11 0 C2H2 type zinc-finger (1 copy) Amidohydro_1 PF01979.20 KFM65115.1 - 2.6 7.3 8.1 28 3.9 0.0 3.5 1 1 3 4 4 4 0 Amidohydrolase family YyzF PF14116.6 KFM65115.1 - 3.6 7.7 42.4 9.3 6.4 0.4 9.9 11 0 0 11 11 11 0 YyzF-like protein FYVE PF01363.21 KFM65115.1 - 5.2 7.3 61.8 1.5 9.0 8.2 5.8 2 1 4 6 6 6 0 FYVE zinc finger zf-H2C2_2 PF13465.6 KFM65117.1 - 1.7e-107 347.4 123.7 1.6e-07 31.4 0.1 17.4 17 0 0 17 17 17 17 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65117.1 - 1.2e-63 208.1 161.0 4.7e-05 23.6 0.7 18.0 18 0 0 18 18 18 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65117.1 - 1.2e-47 156.5 148.2 0.00097 19.8 0.5 17.8 18 0 0 18 18 18 17 C2H2-type zinc finger zf-met PF12874.7 KFM65117.1 - 5.2e-27 93.4 112.4 0.012 16.0 0.2 17.5 17 0 0 17 17 17 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65117.1 - 9.1e-23 80.0 89.2 0.0091 16.3 0.0 17.2 17 0 0 17 17 17 11 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM65117.1 - 1.1e-18 66.7 113.9 0.09 12.8 2.6 17.3 17 0 0 17 17 17 12 C2H2-type zinc finger GAGA PF09237.11 KFM65117.1 - 2.1e-08 33.8 33.2 0.38 10.6 0.2 11.2 4 3 8 13 13 13 3 GAGA factor zf-C2HC_2 PF13913.6 KFM65117.1 - 4.9e-05 23.1 76.8 1.2 9.2 0.1 15.5 17 0 0 17 17 16 5 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFM65117.1 - 6.5e-05 22.6 91.8 0.09 12.6 0.2 17.1 18 0 0 18 18 18 5 C2H2-type zinc-finger domain zf-RRPl_C4 PF17026.5 KFM65117.1 - 7.7e-05 22.8 65.7 0.44 10.7 10.0 7.5 1 1 6 7 7 7 3 Putative ribonucleoprotein zinc-finger pf C4 type BolA PF01722.18 KFM65117.1 - 0.00016 21.9 25.4 5.7 7.3 0.1 9.6 1 1 7 10 10 10 1 BolA-like protein ADK_lid PF05191.14 KFM65117.1 - 0.00018 21.4 57.4 0.3 11.1 0.5 10.3 7 2 4 11 11 11 4 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 KFM65117.1 - 0.00061 19.5 9.2 0.0039 16.9 2.0 12.7 15 0 0 15 15 15 2 zinc-finger C2H2-type DUF952 PF06108.12 KFM65117.1 - 0.0026 17.7 5.0 8.2 6.5 0.0 6.0 3 2 3 7 7 7 0 Protein of unknown function (DUF952) zf-Sec23_Sec24 PF04810.15 KFM65117.1 - 0.0041 17.1 69.7 2.5 8.2 0.1 15.5 12 5 5 17 17 17 2 Sec23/Sec24 zinc finger DUF2039 PF10217.9 KFM65117.1 - 0.057 13.8 60.6 1.3 9.4 4.8 7.9 1 1 8 9 9 9 0 Uncharacterized conserved protein (DUF2039) Zn-C2H2_12 PF18112.1 KFM65117.1 - 0.062 13.8 0.3 0.062 13.8 0.3 13.6 15 0 0 15 15 15 0 Autophagy receptor zinc finger-C2H2 domain zf-DBF PF07535.12 KFM65117.1 - 0.072 13.2 65.5 1.3 9.2 0.0 14.2 15 1 1 16 16 16 0 DBF zinc finger zf-C2H2_9 PF16293.5 KFM65117.1 - 0.11 12.4 0.2 0.11 12.4 0.2 15.1 4 4 13 17 17 17 0 C2H2 type zinc-finger (1 copy) TIP39 PF14980.6 KFM65117.1 - 0.11 12.4 0.1 56 3.7 0.0 3.7 3 0 0 3 3 3 0 TIP39 peptide MCR_D PF02505.14 KFM65117.1 - 0.14 12.0 3.0 53 3.6 0.0 4.7 4 2 2 6 6 6 0 Methyl-coenzyme M reductase operon protein D DUF2256 PF10013.9 KFM65117.1 - 0.41 10.8 65.5 7.2 6.8 0.1 15.4 17 0 0 17 17 17 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.6 KFM65118.1 - 2.1e-83 271.3 121.0 4.6e-07 30.0 0.8 15.5 16 0 0 16 16 16 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65118.1 - 1.5e-57 189.0 143.1 0.00048 20.4 0.6 15.2 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65118.1 - 9.2e-43 141.2 134.9 0.0074 17.0 1.5 15.3 15 0 0 15 15 15 15 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65118.1 - 9.7e-21 73.3 103.9 0.0072 16.3 0.2 15.4 15 0 0 15 15 15 13 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65118.1 - 2.1e-14 53.3 78.5 0.15 12.3 0.3 15.6 15 1 0 15 15 15 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM65118.1 - 3.3e-14 52.7 100.0 0.0055 17.0 0.4 15.6 14 1 1 15 15 15 9 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KFM65118.1 - 5.3e-09 35.8 64.7 0.18 11.7 2.4 14.1 14 0 0 14 14 14 4 zinc-finger of a C2HC-type BolA PF01722.18 KFM65118.1 - 0.00039 20.6 27.4 2.4 8.5 0.5 8.6 1 1 5 8 8 8 1 BolA-like protein ADK_lid PF05191.14 KFM65118.1 - 0.0015 18.4 49.3 0.3 11.1 0.7 9.0 2 2 7 9 9 8 4 Adenylate kinase, active site lid zf-FCS PF06467.14 KFM65118.1 - 0.0042 17.0 52.6 0.7 9.9 2.7 11.9 9 4 3 12 12 12 4 MYM-type Zinc finger with FCS sequence motif zf-Sec23_Sec24 PF04810.15 KFM65118.1 - 0.005 16.9 61.8 1.7 8.8 1.4 13.9 11 4 4 15 15 15 2 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM65118.1 - 0.0055 16.3 1.0 0.0055 16.3 1.0 13.8 9 5 6 15 15 15 2 MYST family zinc finger domain zf-RRPl_C4 PF17026.5 KFM65118.1 - 0.36 11.0 60.5 2.5 8.2 3.2 6.4 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type Mga PF05043.13 KFM65118.1 - 0.45 11.1 3.5 29 5.4 0.1 4.0 4 0 0 4 4 4 0 Mga helix-turn-helix domain zf-C2H2_9 PF16293.5 KFM65118.1 - 5.3 7.0 65.7 4.9 7.1 0.1 13.1 5 4 9 14 14 14 0 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 KFM65119.1 - 4.5e-20 71.1 5.5 5.5e-10 39.2 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65119.1 - 2e-13 50.0 6.6 3.1e-06 27.3 1.3 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65119.1 - 7.6e-11 41.9 5.6 9.1e-05 23.0 0.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65119.1 - 1.2e-09 38.0 2.0 0.00076 19.4 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM65119.1 - 7.4e-08 32.5 4.8 0.00076 19.8 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65119.1 - 7.7e-06 26.1 0.5 0.067 13.5 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM65119.1 - 0.00057 19.8 2.5 0.24 11.4 0.1 2.2 2 0 0 2 2 2 2 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM65119.1 - 0.00071 19.1 1.1 0.27 10.9 0.1 2.1 1 1 1 2 2 2 2 MYST family zinc finger domain zf-C2H2_9 PF16293.5 KFM65119.1 - 0.00089 19.1 0.9 0.49 10.3 0.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KFM65119.1 - 0.0014 18.8 3.7 0.11 12.8 0.3 2.1 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFM65119.1 - 0.0016 18.3 1.6 0.16 11.9 0.1 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFM65119.1 - 0.0019 17.9 3.1 0.29 10.9 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain GAGA PF09237.11 KFM65119.1 - 0.002 17.9 3.8 0.11 12.3 0.1 2.0 1 1 1 2 2 2 2 GAGA factor zf-C2H2_2 PF12756.7 KFM65119.1 - 0.0029 17.9 3.8 0.57 10.5 0.4 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFM65119.1 - 0.006 16.4 2.0 0.022 14.7 1.4 1.9 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) TRAF6_Z2 PF18048.1 KFM65119.1 - 0.0092 16.1 0.2 0.18 12.0 0.1 2.2 2 0 0 2 2 2 1 TNF receptor-associated factor 6 zinc finger 2 zf-Sec23_Sec24 PF04810.15 KFM65119.1 - 0.011 15.8 2.5 0.13 12.3 0.1 2.5 1 1 2 3 3 3 0 Sec23/Sec24 zinc finger zf_UBZ PF18439.1 KFM65119.1 - 0.013 15.1 1.0 3.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HNH PF01844.23 KFM65119.1 - 0.014 15.6 2.1 2.9 8.1 0.1 2.1 2 0 0 2 2 2 0 HNH endonuclease DUF2256 PF10013.9 KFM65119.1 - 0.018 15.1 4.1 2.6 8.2 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_3rep PF18868.1 KFM65119.1 - 0.024 15.3 2.6 2.7 8.7 0.1 2.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats HNH_5 PF14279.6 KFM65119.1 - 0.074 12.9 3.2 6.7 6.7 0.3 2.1 1 1 1 2 2 2 0 HNH endonuclease Zf_RING PF16744.5 KFM65119.1 - 0.21 11.7 3.1 6.6 6.9 2.9 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger A2L_zn_ribbon PF08792.10 KFM65119.1 - 0.4 10.5 4.3 2 8.2 0.4 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2H2_11 PF16622.5 KFM65119.1 - 1.2 8.9 5.3 6.3 6.7 1.3 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KFM65120.1 - 2.2e-12 46.8 5.9 7.2e-08 32.5 0.7 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65120.1 - 0.00012 22.4 11.4 0.0026 18.1 5.1 2.4 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65120.1 - 0.0003 21.4 9.2 0.0087 16.8 4.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65120.1 - 0.0057 16.6 9.2 0.33 11.0 0.6 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65120.1 - 0.0073 16.6 5.2 0.71 10.2 1.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 KFM65120.1 - 0.0076 16.3 2.6 0.82 9.8 0.3 2.2 2 0 0 2 2 2 2 DBF zinc finger zf-met PF12874.7 KFM65120.1 - 0.0087 16.4 7.9 0.83 10.1 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_1 PF00130.22 KFM65120.1 - 0.036 13.9 7.1 1.1 9.2 1.8 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HIT PF04438.16 KFM65120.1 - 0.11 12.4 6.8 2.9 7.8 1.7 2.2 2 0 0 2 2 2 0 HIT zinc finger Zf_RING PF16744.5 KFM65120.1 - 0.18 11.9 6.8 0.51 10.5 1.8 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger Crust_neurohorm PF01147.17 KFM65120.1 - 0.31 10.9 5.5 1.7 8.5 0.3 2.1 1 1 1 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family zf-H2C2_2 PF13465.6 KFM65121.1 - 3.8e-15 55.5 19.4 3.7e-08 33.4 1.4 3.5 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65121.1 - 6.5e-12 45.2 22.4 6.4e-06 26.3 3.3 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.7 KFM65121.1 - 9.5e-11 41.7 15.9 0.00014 22.1 2.2 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65121.1 - 9.1e-10 38.6 12.0 0.0014 18.9 1.0 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFM65121.1 - 2e-08 34.3 20.9 0.00038 21.1 2.5 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65121.1 - 3.6e-05 23.6 18.2 0.3 11.1 0.4 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger Prok-RING_1 PF14446.6 KFM65121.1 - 0.0031 17.4 5.8 2.7 8.0 0.1 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 ADK_lid PF05191.14 KFM65121.1 - 0.0051 16.8 3.1 0.19 11.8 0.3 2.4 1 1 1 2 2 2 2 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KFM65121.1 - 0.013 15.2 1.5 0.013 15.2 1.5 2.8 3 0 0 3 3 2 0 C2H2-type zinc-finger domain DUF2757 PF10955.8 KFM65121.1 - 0.027 14.7 5.7 4.3 7.7 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2757) HNH_5 PF14279.6 KFM65121.1 - 0.03 14.2 10.0 2.6 8.0 0.5 3.1 2 1 1 3 3 3 0 HNH endonuclease Zf_RING PF16744.5 KFM65121.1 - 0.035 14.2 9.2 0.64 10.2 4.0 2.9 1 1 1 2 2 2 0 KIAA1045 RING finger DUF2039 PF10217.9 KFM65121.1 - 0.038 14.3 6.1 0.062 13.7 6.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Zn-ribbon_8 PF09723.10 KFM65121.1 - 0.066 13.3 5.9 1.2 9.3 1.6 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 KFM65121.1 - 0.078 12.6 7.1 1.5 8.5 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 KFM65121.1 - 0.083 13.0 5.7 14 5.9 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Sec23_Sec24 PF04810.15 KFM65121.1 - 0.18 11.9 7.7 2.8 8.1 0.7 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM65121.1 - 0.18 11.7 10.0 9.1 6.3 0.3 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Vps39_2 PF10367.9 KFM65121.1 - 0.27 11.7 11.5 6.3 7.3 0.3 3.1 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 XPA_N PF01286.18 KFM65121.1 - 0.5 10.5 8.1 24 5.1 0.2 3.3 3 0 0 3 3 3 0 XPA protein N-terminal zf-MYST PF17772.1 KFM65121.1 - 0.81 9.3 12.1 0.14 11.8 1.1 3.1 2 2 1 3 3 3 0 MYST family zinc finger domain zf-HIT PF04438.16 KFM65121.1 - 0.88 9.5 8.7 7.9 6.4 0.3 3.2 3 0 0 3 3 3 0 HIT zinc finger LIM PF00412.22 KFM65121.1 - 1.1 9.5 10.1 3.6 7.9 4.6 2.7 1 1 1 2 2 2 0 LIM domain zf-C2H2_9 PF16293.5 KFM65121.1 - 1.5 8.7 7.4 3.4 7.6 0.7 2.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM65121.1 - 1.5 9.0 11.8 3.9 7.7 11.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFM65121.1 - 2.6 8.4 15.7 1 9.7 1.2 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CCHC_2 PF13696.6 KFM65121.1 - 4 7.3 11.8 2.1 8.3 0.3 3.3 3 0 0 3 3 3 0 Zinc knuckle DUF2225 PF09986.9 KFM65121.1 - 4.1 7.1 8.6 0.93 9.2 2.4 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-DBF PF07535.12 KFM65121.1 - 4.9 7.4 14.0 3.8 7.7 1.9 3.1 2 1 1 3 3 3 0 DBF zinc finger C1_2 PF03107.16 KFM65121.1 - 5.9 7.3 18.5 2.2 8.7 1.2 3.3 2 1 1 3 3 3 0 C1 domain A2L_zn_ribbon PF08792.10 KFM65121.1 - 7.6 6.4 13.9 1.9 8.3 0.5 3.4 4 0 0 4 4 3 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 KFM65124.1 - 7.2e-95 307.6 146.6 6.1e-09 35.9 2.3 18.3 18 1 0 18 18 18 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65124.1 - 5.6e-57 187.1 153.3 1.3e-05 25.4 3.5 16.2 16 0 0 16 16 16 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65124.1 - 7.9e-54 175.6 142.2 0.00036 21.1 2.5 16.3 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65124.1 - 3.4e-26 90.7 134.1 0.00078 19.4 0.2 16.8 16 1 0 16 16 16 13 C2H2-type zinc finger zf-met PF12874.7 KFM65124.1 - 1.3e-19 69.9 126.0 0.013 15.9 1.0 16.3 16 1 0 16 16 16 12 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM65124.1 - 5.9e-08 32.3 100.7 0.11 12.2 0.2 16.5 16 3 0 16 16 16 9 C2H2-type zinc-finger domain BolA PF01722.18 KFM65124.1 - 5.8e-07 29.7 21.7 0.26 11.6 0.1 9.4 2 2 7 9 9 9 2 BolA-like protein zf-C2H2_jaz PF12171.8 KFM65124.1 - 9.4e-06 25.8 97.4 0.024 14.9 0.6 15.9 13 1 3 16 16 16 7 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM65124.1 - 1.6e-05 24.7 63.7 0.38 10.7 0.4 12.8 13 0 0 13 13 13 6 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFM65124.1 - 0.00031 20.4 0.9 0.00031 20.4 0.9 13.9 15 0 0 15 15 15 6 zinc-finger C2H2-type BHD_1 PF10403.9 KFM65124.1 - 0.0047 16.7 2.1 29 4.6 0.0 5.0 5 0 0 5 5 5 0 Rad4 beta-hairpin domain 1 Complex1_49kDa PF00346.19 KFM65124.1 - 0.036 13.2 1.2 0.36 9.9 0.1 2.6 3 1 0 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit CIA30 PF08547.12 KFM65124.1 - 0.072 13.1 0.0 8.1 6.4 0.0 3.2 2 1 1 3 3 3 0 Complex I intermediate-associated protein 30 (CIA30) Ribosomal_S14 PF00253.21 KFM65124.1 - 0.55 10.0 0.0 0.55 10.0 0.0 6.0 8 0 0 8 8 7 0 Ribosomal protein S14p/S29e zf-H2C2_2 PF13465.6 KFM65125.1 - 2.9e-33 112.8 38.5 8.3e-09 35.5 0.7 5.6 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65125.1 - 1.3e-24 85.2 42.2 5.5e-06 26.5 0.5 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65125.1 - 8.3e-19 66.7 39.6 0.00021 21.9 1.0 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM65125.1 - 6.4e-14 51.8 35.0 0.0041 17.5 1.5 5.6 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65125.1 - 7e-11 41.9 32.9 0.011 15.7 0.7 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65125.1 - 1.2e-09 38.2 28.2 0.0018 18.5 0.6 5.2 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding Prok-RING_1 PF14446.6 KFM65125.1 - 0.00075 19.4 15.5 0.79 9.7 0.1 5.2 5 0 0 5 5 5 1 Prokaryotic RING finger family 1 BolA PF01722.18 KFM65125.1 - 0.00075 19.7 0.8 0.13 12.6 0.2 3.2 1 1 2 3 3 3 1 BolA-like protein Zf_RING PF16744.5 KFM65125.1 - 0.032 14.3 18.2 7.8 6.7 0.6 5.0 1 1 4 5 5 5 0 KIAA1045 RING finger ADK_lid PF05191.14 KFM65125.1 - 0.077 13.0 13.5 0.15 12.0 0.5 3.5 2 2 1 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM65125.1 - 0.081 13.3 24.5 0.67 10.3 0.6 4.7 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Baculo_IE-1 PF05290.11 KFM65125.1 - 0.095 12.6 11.4 1.8 8.5 2.8 4.0 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) Ndufs5 PF10200.9 KFM65125.1 - 0.12 12.6 3.0 2.4 8.5 0.1 3.2 1 1 2 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa zf-met2 PF12907.7 KFM65125.1 - 0.19 11.9 17.0 4.1 7.6 0.1 5.3 5 0 0 5 5 5 0 Zinc-binding GAGA PF09237.11 KFM65125.1 - 0.29 11.0 0.2 0.29 11.0 0.2 3.5 1 1 3 4 4 4 0 GAGA factor zf-C2HC_2 PF13913.6 KFM65125.1 - 0.4 10.6 22.4 1.3 9.0 0.1 4.8 4 1 1 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM65125.1 - 0.53 10.2 11.7 14 5.6 0.0 4.6 1 1 4 5 5 5 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM65125.1 - 0.54 10.4 24.0 2.5 8.3 16.3 3.4 1 1 0 2 2 2 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM65125.1 - 0.75 10.6 15.6 0.24 12.2 1.6 2.9 1 1 2 3 3 3 0 zinc-ribbon family zf-BED PF02892.15 KFM65125.1 - 1.1 9.3 32.1 0.7 10.0 5.6 5.1 1 1 4 5 5 5 0 BED zinc finger zf-C2H2_11 PF16622.5 KFM65125.1 - 1.4 8.7 0.0 1.4 8.7 0.0 4.9 5 0 0 5 5 5 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFM65125.1 - 3.5 7.8 21.4 0.5 10.5 1.7 3.9 1 1 3 4 4 4 0 Zinc ribbon domain zf-CHCC PF10276.9 KFM65125.1 - 6.3 6.9 10.5 59 3.8 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger domain zf-RING_5 PF14634.6 KFM65125.1 - 6.5 6.8 22.2 37 4.4 0.9 5.0 2 1 2 4 4 4 0 zinc-RING finger domain DDE_3 PF13358.6 KFM65126.1 - 1.2e-14 54.3 0.1 1.2e-13 51.1 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65126.1 - 1.4e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65127.1 - 4.8e-16 58.8 0.1 5.6e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65127.1 - 7.6e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM65127.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM65127.1 - 0.0025 17.6 0.1 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM65127.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM65127.1 - 0.035 14.1 0.4 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDE_1 PF03184.19 KFM65128.1 - 1.8e-17 63.5 0.1 3e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM65128.1 - 5.3e-12 45.6 0.4 1.1e-11 44.5 0.4 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM65128.1 - 0.0039 17.0 0.0 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 KFM65128.1 - 0.038 14.3 0.1 0.095 13.0 0.1 1.6 1 0 0 1 1 1 0 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM65129.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65129.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease UPF0203 PF05254.12 KFM65131.1 - 2.3e-19 69.4 2.3 2.6e-19 69.2 2.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KFM65131.1 - 0.0083 16.5 1.1 0.77 10.2 0.1 2.1 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) DUF1910 PF08928.10 KFM65131.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) CHCH PF06747.13 KFM65131.1 - 0.012 15.7 3.3 0.047 13.8 0.4 2.2 2 0 0 2 2 2 0 CHCH domain Mvb12 PF09452.10 KFM65131.1 - 0.023 15.1 0.4 0.043 14.2 0.2 1.6 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 Cmc1 PF08583.10 KFM65131.1 - 0.075 13.1 2.7 1.7 8.7 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KFM65131.1 - 0.076 13.3 5.2 0.39 11.0 5.2 1.9 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.16 KFM65131.1 - 0.12 12.6 4.8 1.8 8.8 1.2 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein FAM193_C PF15914.5 KFM65132.1 - 0.00069 19.3 2.4 0.002 17.8 2.4 1.9 1 0 0 1 1 1 1 FAM193 family C-terminal ZapB PF06005.12 KFM65132.1 - 0.0025 18.2 5.9 0.0025 18.2 5.9 3.9 1 1 2 3 3 3 2 Cell division protein ZapB SOGA PF11365.8 KFM65132.1 - 0.03 15.4 21.3 0.23 12.6 5.8 2.5 2 1 0 2 2 2 0 Protein SOGA CCDC74_C PF14917.6 KFM65132.1 - 0.07 13.6 6.9 0.95 10.0 0.9 2.4 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal GAS PF13851.6 KFM65132.1 - 0.12 11.7 26.0 0.45 9.8 17.9 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4371 PF14291.6 KFM65133.1 - 2.8e-30 105.7 0.5 5.4e-30 104.8 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM65133.1 - 2e-09 37.1 0.2 7.4e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM65133.1 - 0.038 13.0 7.6 0.051 12.5 0.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MAT1 PF06391.13 KFM65133.1 - 2.4 7.9 7.7 2.4 7.9 2.0 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4355 PF14265.6 KFM65133.1 - 3.4 7.9 5.7 3.7 7.8 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Exonuc_VII_L PF02601.15 KFM65133.1 - 4.1 6.9 7.1 6.4 6.3 1.2 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit HTH_Tnp_Tc3_2 PF01498.18 KFM65134.1 - 4.7e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65134.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65134.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65134.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65134.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain CUB PF00431.20 KFM65135.1 - 1.1e-08 35.4 0.0 1.3e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 CUB domain HTH_Tnp_Tc3_2 PF01498.18 KFM65137.1 - 5.1e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65137.1 - 3.3e-13 49.6 0.0 5.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65137.1 - 2e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65137.1 - 0.0026 17.5 0.6 0.0077 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65137.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM65138.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65138.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65138.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65138.1 - 0.0027 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65138.1 - 2.2 8.9 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain CENP-R PF06729.12 KFM65140.1 - 0.00089 19.2 2.8 0.00089 19.2 2.8 2.0 3 0 0 3 3 3 1 Kinetochore component, CENP-R DUF3899 PF13038.6 KFM65140.1 - 0.004 17.6 0.3 0.009 16.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3899) Mito_fiss_reg PF05308.11 KFM65140.1 - 0.0057 16.8 6.4 0.0057 16.8 6.4 2.6 3 1 0 3 3 3 1 Mitochondrial fission regulator Drf_FH3 PF06367.16 KFM65142.1 - 1.2e-10 41.3 0.0 1.3e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Diaphanous FH3 Domain ANAPC10 PF03256.16 KFM65144.1 - 5.8e-71 238.0 0.0 6.8e-71 237.7 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KFM65144.1 - 0.0029 17.7 0.0 0.0038 17.3 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain AAA_11 PF13086.6 KFM65147.1 - 6.9e-13 49.0 3.4 1.4e-12 48.0 3.4 1.7 1 1 0 1 1 1 1 AAA domain DUF3793 PF12672.7 KFM65147.1 - 0.017 15.2 0.2 0.04 14.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) AAA_30 PF13604.6 KFM65147.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFM65147.1 - 0.35 11.2 3.6 1.2 9.4 3.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_12 PF13087.6 KFM65148.1 - 1.3e-06 28.2 0.1 1.3e-06 28.2 0.1 1.0 1 0 0 1 1 1 1 AAA domain HTH_Tnp_Tc3_2 PF01498.18 KFM65149.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65149.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65149.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65149.1 - 0.0027 17.4 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM65149.1 - 0.029 14.5 0.4 0.085 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM65149.1 - 2.4 8.9 15.1 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RVT_2 PF07727.14 KFM65150.1 - 4.4e-17 62.5 1.1 1.5e-16 60.8 0.3 2.1 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MAJIN PF15077.6 KFM65151.1 - 0.49 10.1 5.9 0.67 9.7 5.9 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein Red1 PF07964.11 KFM65151.1 - 1.3 7.2 13.5 1.6 6.9 13.5 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Peptidase_M17 PF00883.21 KFM65153.1 - 4e-120 400.8 0.0 5e-120 400.5 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KFM65153.1 - 8.5e-07 28.9 0.0 1.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DDE_1 PF03184.19 KFM65154.1 - 1.8e-25 89.6 0.3 3.5e-25 88.7 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM65154.1 - 1.6e-09 37.7 0.1 4.3e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain BrkDBD PF09607.10 KFM65154.1 - 1.8e-06 27.6 0.1 5.9e-06 26.0 0.1 1.9 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_1 PF01527.20 KFM65154.1 - 0.083 13.2 0.5 0.38 11.1 0.1 2.1 1 1 0 2 2 2 0 Transposase EGF_CA PF07645.15 KFM65156.1 - 1.8e-06 28.0 6.3 1.8e-06 28.0 6.3 11.4 3 2 8 11 11 11 1 Calcium-binding EGF domain hEGF PF12661.7 KFM65156.1 - 0.00016 22.2 19.3 0.00024 21.6 4.1 13.9 13 4 1 14 14 14 4 Human growth factor-like EGF EGF PF00008.27 KFM65156.1 - 0.00027 21.2 21.8 0.0012 19.1 5.4 12.7 10 5 1 12 12 12 4 EGF-like domain cEGF PF12662.7 KFM65156.1 - 0.0043 16.9 0.6 0.0043 16.9 0.6 12.3 12 2 0 12 12 12 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFM65156.1 - 0.0073 16.6 2.8 0.0073 16.6 2.8 12.1 2 2 7 10 10 10 4 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KFM65156.1 - 0.011 16.1 5.0 0.011 16.1 5.0 10.6 8 2 3 11 11 11 0 Pvs28 EGF domain EB PF01683.18 KFM65156.1 - 0.018 15.3 5.0 0.018 15.3 5.0 11.4 9 2 2 11 11 11 0 EB module 7TM_GPCR_Srw PF10324.9 KFM65157.1 - 1.3e-30 106.8 22.3 1.8e-30 106.3 22.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KFM65157.1 - 2.1e-26 92.8 16.5 2.8e-26 92.4 16.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 KFM65157.1 - 0.00014 21.1 20.2 0.00021 20.5 20.2 1.2 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7TM_GPCR_Srx PF10328.9 KFM65157.1 - 0.00043 20.0 27.8 0.00053 19.7 19.4 2.6 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx MARVEL PF01284.23 KFM65157.1 - 0.0038 17.3 4.7 0.0038 17.3 4.7 2.6 2 1 0 2 2 2 1 Membrane-associating domain TMEM154 PF15102.6 KFM65157.1 - 1.2 9.0 6.1 1.6 8.6 0.1 3.0 2 1 1 3 3 3 0 TMEM154 protein family TctB PF07331.11 KFM65157.1 - 3.7 7.8 10.0 17 5.7 2.4 2.7 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family EF-hand_7 PF13499.6 KFM65158.1 - 1.2e-08 35.3 11.8 1.7e-05 25.2 4.4 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM65158.1 - 1.3e-08 34.1 3.9 0.00021 20.9 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFM65158.1 - 2.9e-07 29.5 0.8 1.1e-05 24.6 0.5 2.4 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 KFM65158.1 - 0.00016 21.6 0.6 0.061 13.3 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KFM65158.1 - 0.0042 16.5 1.0 0.0095 15.4 1.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KFM65158.1 - 0.012 15.5 0.3 0.02 14.7 0.3 1.4 1 0 0 1 1 1 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM65158.1 - 0.14 12.5 1.5 0.3 11.4 1.5 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Ig_3 PF13927.6 KFM65159.1 - 0.01 16.4 0.1 1.5 9.5 0.1 2.2 2 0 0 2 2 2 0 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM65159.1 - 0.011 15.7 0.1 0.016 15.2 0.1 1.4 1 1 0 1 1 1 0 C17orf99 Ig domain ig PF00047.25 KFM65159.1 - 0.065 13.4 0.3 3.6 7.8 0.0 2.1 1 1 1 2 2 2 0 Immunoglobulin domain zf-C2H2 PF00096.26 KFM65160.1 - 3.5e-30 102.8 40.2 2.1e-07 31.0 0.3 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM65160.1 - 7.6e-28 95.7 40.1 4.8e-10 39.4 0.9 6.0 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM65160.1 - 4.7e-21 73.7 35.7 0.00012 22.7 0.2 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65160.1 - 2.4e-16 59.5 5.7 0.0014 18.8 0.3 5.3 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM65160.1 - 7.2e-16 57.8 31.2 5.1e-05 23.2 0.7 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM65160.1 - 1.3e-12 47.7 20.0 0.0055 17.0 0.4 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM65160.1 - 6.1e-06 25.9 24.4 0.14 12.0 0.5 5.6 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-Di19 PF05605.12 KFM65160.1 - 8.4e-05 22.8 15.5 0.012 15.9 0.6 3.3 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KFM65160.1 - 0.0038 17.7 6.4 28 5.3 0.2 5.3 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 KFM65160.1 - 0.0042 17.2 8.9 0.75 10.0 0.3 3.7 2 1 0 3 3 3 2 Zinc ribbon domain zf-CHCC PF10276.9 KFM65160.1 - 0.034 14.2 8.7 3.6 7.7 0.1 4.6 5 0 0 5 5 5 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KFM65160.1 - 0.039 13.9 20.1 0.62 10.0 0.1 5.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM65160.1 - 0.063 14.0 8.5 1.2 9.9 1.5 3.2 1 1 1 2 2 2 0 zinc-ribbon family zf-H2C2_5 PF13909.6 KFM65160.1 - 0.09 12.6 0.4 0.09 12.6 0.4 4.8 4 1 0 4 4 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM65160.1 - 0.096 13.0 16.6 8.2 6.8 0.4 4.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.18 KFM65160.1 - 0.15 12.2 9.9 12 6.0 0.1 5.0 5 0 0 5 5 5 0 XPA protein N-terminal CpXC PF14353.6 KFM65160.1 - 0.2 11.7 4.0 0.69 10.0 0.2 3.1 1 1 2 3 3 3 0 CpXC protein FYVE PF01363.21 KFM65160.1 - 1.3 9.2 24.8 1.7 8.9 7.4 4.7 2 1 2 4 4 4 0 FYVE zinc finger DUF2180 PF09947.9 KFM65160.1 - 1.8 8.6 5.4 3.6 7.6 0.7 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2HE PF16278.5 KFM65160.1 - 3.3 8.2 22.5 9.5 6.8 1.4 4.8 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-trcl PF13451.6 KFM65160.1 - 3.5 7.6 11.8 0.33 10.9 0.9 3.7 4 0 0 4 4 4 0 Probable zinc-ribbon domain zf-H2C2_2 PF13465.6 KFM65162.1 - 7.7e-67 218.9 79.6 1.9e-07 31.2 0.6 13.3 14 0 0 14 14 14 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65162.1 - 1.6e-45 151.1 109.4 4.1e-05 23.8 0.7 13.2 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65162.1 - 1.6e-37 124.9 100.9 0.0013 19.4 3.6 12.8 13 0 0 13 13 13 12 C2H2-type zinc finger zf-met PF12874.7 KFM65162.1 - 4.3e-17 61.9 89.7 0.0046 17.3 2.7 13.5 13 0 0 13 13 13 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65162.1 - 1.1e-15 57.1 73.4 0.0034 17.3 1.0 12.9 12 0 0 12 12 12 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65162.1 - 8.9e-10 38.6 63.6 0.22 11.8 1.3 12.5 13 0 0 13 13 13 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM65162.1 - 1.4e-06 28.0 50.0 0.074 12.8 0.3 10.9 11 0 0 11 11 11 4 C2H2-type zinc-finger domain GAGA PF09237.11 KFM65162.1 - 7.4e-06 25.7 29.0 0.14 12.0 0.0 9.2 4 2 7 11 11 11 2 GAGA factor zf-CHCC PF10276.9 KFM65162.1 - 3.8e-05 23.6 7.6 56 3.9 0.0 8.4 9 0 0 9 9 9 0 Zinc-finger domain BolA PF01722.18 KFM65162.1 - 5e-05 23.5 13.6 2.5 8.4 0.1 6.2 2 2 4 6 6 6 2 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM65162.1 - 0.00012 22.0 42.5 1.9 8.6 0.3 10.3 7 3 4 11 11 11 3 Sec23/Sec24 zinc finger MCR_D PF02505.14 KFM65162.1 - 0.0042 16.9 1.7 1.2 8.9 0.0 4.0 2 1 0 4 4 4 1 Methyl-coenzyme M reductase operon protein D FYVE PF01363.21 KFM65162.1 - 0.017 15.2 67.4 0.054 13.6 12.5 6.8 2 1 2 5 5 5 0 FYVE zinc finger YyzF PF14116.6 KFM65162.1 - 0.022 14.8 35.4 25 5.0 0.1 10.9 11 0 0 11 11 11 0 YyzF-like protein zf-RRPl_C4 PF17026.5 KFM65162.1 - 0.03 14.4 49.8 1 9.5 9.2 5.0 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM65162.1 - 0.14 12.3 44.8 21 5.3 0.0 10.0 10 0 0 10 10 10 0 DBF zinc finger ADK_lid PF05191.14 KFM65162.1 - 0.23 11.5 41.1 0.21 11.6 1.3 7.9 3 2 4 7 7 7 0 Adenylate kinase, active site lid TRAF6_Z2 PF18048.1 KFM65162.1 - 0.23 11.6 63.0 0.22 11.6 0.8 10.8 12 0 0 12 12 11 0 TNF receptor-associated factor 6 zinc finger 2 DUF2256 PF10013.9 KFM65162.1 - 1.5 9.0 51.3 12 6.1 0.2 10.8 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) Pox_D3 PF04580.13 KFM65162.1 - 4.1 7.0 11.4 0.38 10.4 3.8 2.7 2 1 2 4 4 4 0 Chordopoxvirinae D3 protein C1_1 PF00130.22 KFM65162.1 - 6.6 6.7 73.2 1.2 9.0 0.4 10.3 5 3 4 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HTH_Tnp_Tc3_2 PF01498.18 KFM65167.1 - 5.5e-16 58.6 4.1 5.7e-16 58.5 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM65167.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65167.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65167.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65167.1 - 2.1 9.0 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Arf PF00025.21 KFM65169.1 - 1e-78 262.8 0.1 1.1e-78 262.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFM65169.1 - 4.7e-14 52.6 0.1 6.4e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFM65169.1 - 2.5e-13 49.9 0.0 2.9e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFM65169.1 - 7.8e-13 48.3 0.0 8.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFM65169.1 - 1.1e-11 44.6 2.0 7.6e-08 31.9 0.5 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFM65169.1 - 3.1e-10 39.8 0.0 3.7e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM65169.1 - 2e-05 24.6 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFM65169.1 - 0.0046 16.3 0.3 0.012 14.9 0.1 1.7 2 1 0 2 2 2 1 6-phosphofructo-2-kinase Na_K-ATPase PF00287.18 KFM65170.1 - 0.088 12.0 2.5 0.092 11.9 2.5 1.0 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain MADF_DNA_bdg PF10545.9 KFM65171.1 - 2.7e-05 24.4 1.2 4.1e-05 23.8 1.2 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Kelch_4 PF13418.6 KFM65172.1 - 4e-38 129.2 0.1 6.6e-11 42.0 0.0 6.6 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFM65172.1 - 8.7e-36 121.6 0.1 1.6e-06 28.2 0.0 7.6 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM65172.1 - 1.5e-27 95.1 3.9 2.8e-08 33.5 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFM65172.1 - 1.9e-27 94.6 1.1 3e-06 27.3 0.1 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFM65172.1 - 9.2e-17 60.3 15.3 2e-06 27.5 0.1 7.6 7 1 0 7 7 7 4 Kelch motif Kelch_1 PF01344.25 KFM65172.1 - 1.9e-15 56.2 10.9 7.4e-07 28.7 0.0 7.6 7 2 0 7 7 7 3 Kelch motif DUF2722 PF10846.8 KFM65172.1 - 7.9 5.3 6.4 21 3.9 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) MORN PF02493.20 KFM65174.1 - 6.9e-37 123.2 66.4 2.8e-06 26.9 1.9 9.1 10 0 0 10 10 10 8 MORN repeat FMO-like PF00743.19 KFM65175.1 - 4e-61 207.1 0.0 5.6e-50 170.2 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM65175.1 - 4.3e-15 55.8 3.8 1.5e-13 50.7 3.8 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM65175.1 - 2.7e-12 46.5 0.1 1.4e-11 44.1 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM65175.1 - 2.9e-09 36.5 0.6 3.7e-08 32.9 0.0 2.6 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFM65175.1 - 9.1e-09 35.3 0.4 0.026 14.1 0.0 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM65175.1 - 9.2e-09 35.4 0.7 7.2e-07 29.4 0.0 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFM65175.1 - 3.1e-08 33.8 1.0 2.9e-06 27.3 0.1 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KFM65175.1 - 3.3e-06 26.5 0.1 0.0057 15.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KFM65175.1 - 2.2e-05 23.4 0.6 0.11 11.1 0.1 2.5 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 KFM65175.1 - 0.00012 22.6 1.6 0.001 19.6 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM65175.1 - 0.00027 20.1 0.1 0.39 9.7 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 KFM65175.1 - 0.0013 18.0 3.3 0.72 9.1 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFM65175.1 - 0.0059 15.7 1.7 0.21 10.7 0.4 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 KFM65175.1 - 0.055 13.5 0.1 9.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KFM65175.1 - 0.073 12.1 0.1 11 5.0 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Malic_M PF03949.15 KFM65175.1 - 0.078 12.2 0.1 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KFM65175.1 - 0.17 11.9 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fimbrial PF00419.20 KFM65176.1 - 0.039 14.2 0.1 0.04 14.2 0.1 1.0 1 0 0 1 1 1 0 Fimbrial protein DOCK-C2 PF14429.6 KFM65177.1 - 4e-53 180.1 0.0 7.1e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 KFM65177.1 - 6.3e-49 166.9 0.6 1.4e-48 165.7 0.6 1.6 1 1 0 1 1 1 1 DOCK N-terminus PI3K_C2 PF00792.24 KFM65177.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Aida_C2 PF14186.6 KFM65177.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal adhesion RVT_1 PF00078.27 KFM65180.1 - 0.021 14.4 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DHR-2 PF06920.13 KFM65182.1 - 8.8e-67 225.9 2.0 4.7e-66 223.5 2.0 1.8 1 1 0 1 1 1 1 Dock homology region 2 Abhydrolase_1 PF00561.20 KFM65184.1 - 3.1e-15 56.5 0.0 3.8e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM65184.1 - 1.8e-12 48.4 0.0 2e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM65184.1 - 6.1e-08 32.2 0.0 8.1e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 KFM65184.1 - 0.0013 17.3 0.0 0.0046 15.5 0.0 1.7 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 KFM65184.1 - 0.0028 17.5 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KFM65184.1 - 0.0031 17.3 0.4 0.24 11.1 0.4 2.1 1 1 1 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 KFM65184.1 - 0.013 15.3 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF915 PF06028.11 KFM65184.1 - 0.04 13.2 0.2 0.33 10.2 0.1 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KFM65184.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase HTH_Tnp_Tc3_2 PF01498.18 KFM65185.1 - 2.2e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65185.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65186.1 - 2.2e-19 69.4 3.8 5e-19 68.3 2.1 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65186.1 - 4.7e-16 58.9 0.0 2.5e-15 56.5 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM65186.1 - 3.1e-07 30.9 2.0 3.1e-07 30.9 2.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM65186.1 - 0.00044 20.1 0.7 0.005 16.7 0.0 2.4 1 1 1 2 2 2 1 MarR family HTH_29 PF13551.6 KFM65186.1 - 0.0011 19.0 0.3 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 KFM65186.1 - 0.0012 18.7 0.3 0.018 15.0 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM65186.1 - 0.0017 18.5 1.2 0.28 11.3 0.0 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65186.1 - 0.025 14.4 1.8 1.1 9.1 0.0 2.9 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 KFM65186.1 - 0.033 14.3 0.7 8.4 6.6 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 KFM65186.1 - 0.12 12.6 0.1 19 5.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM65187.1 - 4.1e-16 59.0 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65187.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65187.1 - 1.6e-07 31.0 1.2 6.8e-07 29.0 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65187.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65187.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain TGS PF02824.21 KFM65188.1 - 4e-08 33.2 0.0 8.9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain HTH_Tnp_Tc3_2 PF01498.18 KFM65189.1 - 2.1e-16 59.9 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65189.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_92 PF01697.27 KFM65190.1 - 1.9e-52 178.5 4.5 2.9e-52 177.9 4.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 fn3 PF00041.21 KFM65191.1 - 1.3e-15 57.5 3.5 5.1e-07 30.0 0.4 2.2 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM65191.1 - 0.0015 19.1 4.4 0.046 14.3 1.4 2.2 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Flp_N PF03930.14 KFM65191.1 - 0.0023 17.9 0.0 0.0033 17.4 0.0 1.2 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus Neogenin_C PF06583.12 KFM65192.1 - 0.00017 21.5 0.5 0.00017 21.5 0.5 1.0 1 0 0 1 1 1 1 Neogenin C-terminus Neogenin_C PF06583.12 KFM65193.1 - 0.0017 18.3 1.1 0.0017 18.3 1.1 1.1 1 0 0 1 1 1 1 Neogenin C-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM65195.1 - 2.6e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65195.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65195.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65195.1 - 0.0023 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65195.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM65196.1 - 8.6e-17 61.2 1.7 1.7e-16 60.2 1.7 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM65196.1 - 1.3e-06 29.0 6.7 5.4e-06 26.9 1.8 2.2 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM65196.1 - 1.3e-05 25.0 0.5 0.0015 18.3 0.0 2.5 2 1 0 2 2 2 1 MarR family HTH_3 PF01381.22 KFM65196.1 - 7e-05 22.8 1.1 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM65196.1 - 0.00012 22.0 0.7 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM65196.1 - 0.0013 18.2 1.7 0.043 13.4 0.0 2.8 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KFM65196.1 - 0.0067 16.5 2.3 0.19 11.9 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 KFM65196.1 - 0.021 14.6 0.2 0.18 11.6 0.0 2.2 2 1 0 2 2 2 0 IclR helix-turn-helix domain TrmB PF01978.19 KFM65196.1 - 0.03 14.2 0.1 0.56 10.1 0.0 2.3 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 KFM65196.1 - 0.047 13.8 0.0 8.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 KFM65196.1 - 0.048 14.1 0.3 7.4 7.1 0.1 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain PAX PF00292.18 KFM65196.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 'Paired box' domain HTH_23 PF13384.6 KFM65196.1 - 0.11 12.4 4.5 0.55 10.1 0.1 2.8 3 0 0 3 3 3 0 Homeodomain-like domain EMP70 PF02990.16 KFM65197.1 - 1.4e-79 268.2 23.4 1.5e-79 268.0 23.4 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 EMP70 PF02990.16 KFM65198.1 - 7.1e-16 58.0 0.1 7.8e-16 57.8 0.1 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3896 PF13035.6 KFM65198.1 - 0.044 13.9 0.1 0.078 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) ULD PF16534.5 KFM65200.1 - 1.6e-12 47.4 0.0 4.2e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like oligomerisation domain of SATB YukD PF08817.10 KFM65201.1 - 0.12 13.0 0.0 0.13 12.9 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Kinesin PF00225.23 KFM65202.1 - 7.1e-76 255.3 1.5 7.1e-76 255.3 1.5 3.0 3 0 0 3 3 3 1 Kinesin motor domain APG6_N PF17675.1 KFM65202.1 - 0.00026 21.5 21.6 0.00026 21.5 21.6 5.3 3 1 2 5 5 5 2 Apg6 coiled-coil region Spc7 PF08317.11 KFM65202.1 - 0.0015 17.5 94.7 0.03 13.2 27.9 4.4 2 1 2 4 4 4 4 Spc7 kinetochore protein Cnn_1N PF07989.11 KFM65202.1 - 0.015 15.5 1.9 0.015 15.5 1.9 7.9 5 3 1 8 8 8 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 KFM65202.1 - 6.7 6.8 59.7 1.7 8.7 2.1 6.8 2 1 5 7 7 7 0 Protein of unknown function (DUF1664) S_4TM PF18159.1 KFM65203.1 - 5.5 6.2 6.2 0.43 9.8 0.7 1.7 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain HTH_Tnp_Tc3_2 PF01498.18 KFM65204.1 - 2.2e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65204.1 - 8.4e-14 51.5 0.0 1.4e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65205.1 - 2.2e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65205.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PID_2 PF14719.6 KFM65207.1 - 5.9e-87 290.2 1.2 7.7e-87 289.8 1.2 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFM65207.1 - 0.008 16.3 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain DUF4371 PF14291.6 KFM65208.1 - 7.8e-10 38.8 0.0 2.1e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM65208.1 - 0.047 13.5 0.4 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region ParcG PF10274.9 KFM65209.1 - 1.5e-20 74.1 0.0 1.6e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein UvsW PF11637.8 KFM65209.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW RT_RNaseH_2 PF17919.1 KFM65210.1 - 1.2e-09 38.1 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM65210.1 - 2.6e-05 24.4 0.0 4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM65211.1 - 1.5e-20 73.1 0.7 1.5e-20 73.1 0.7 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM65211.1 - 2.9e-06 27.4 0.1 7.9e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger PH PF00169.29 KFM65212.1 - 1.3e-08 35.3 0.2 1.6e-08 35.0 0.2 1.2 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFM65212.1 - 0.028 14.2 0.2 0.033 14.0 0.2 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain RhoGEF PF00621.20 KFM65213.1 - 7e-28 98.1 0.0 7.8e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 RhoGEF domain Ion_trans_2 PF07885.16 KFM65216.1 - 1.8e-09 37.4 0.5 2.4e-09 37.0 0.5 1.2 1 0 0 1 1 1 1 Ion channel DUF5321 PF17254.2 KFM65216.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5321) DUF3456 PF11938.8 KFM65217.1 - 6.7e-11 42.9 4.6 4.2e-05 24.1 0.0 2.5 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.13 KFM65217.1 - 0.0001 22.6 10.5 0.0001 22.6 10.5 3.9 3 0 0 3 3 3 1 EGF-like domain Laminin_EGF PF00053.24 KFM65217.1 - 0.003 17.6 8.0 0.003 17.6 8.0 3.9 1 1 2 3 3 3 1 Laminin EGF domain Zf_RING PF16744.5 KFM65217.1 - 0.018 15.2 10.8 0.053 13.6 4.0 3.7 4 0 0 4 4 4 0 KIAA1045 RING finger Zona_pellucida PF00100.23 KFM65219.1 - 8.1e-25 88.1 2.4 9.9e-25 87.8 2.4 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EphA2_TM PF14575.6 KFM65219.1 - 0.18 12.7 2.2 0.2 12.6 0.4 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KFM65219.1 - 0.21 11.5 0.8 0.48 10.4 0.8 1.5 1 0 0 1 1 1 0 Syndecan domain RCR PF12273.8 KFM65219.1 - 0.25 12.0 0.4 0.53 10.9 0.4 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.10 KFM65219.1 - 0.43 10.0 5.4 1.2 8.6 5.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Neur_chan_LBD PF02931.23 KFM65220.1 - 3.2e-29 101.9 0.2 4.4e-29 101.5 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM65220.1 - 1.1 9.2 11.9 1.7 8.6 11.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Thyroglobulin_1 PF00086.18 KFM65222.1 - 1.7e-17 62.9 37.6 2.5e-06 27.0 0.4 5.4 5 1 1 6 6 6 4 Thyroglobulin type-1 repeat amfpi-1 PF12190.8 KFM65222.1 - 0.047 14.3 10.6 0.29 11.8 10.6 2.3 1 0 0 1 1 1 0 Fungal protease inhibitor DUF3644 PF12358.8 KFM65222.1 - 0.13 12.8 0.1 0.34 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) SHP PF03579.13 KFM65222.1 - 2.3 8.2 5.9 0.69 9.9 0.3 2.3 2 0 0 2 2 2 0 Small hydrophobic protein SET PF00856.28 KFM65223.1 - 7.8e-13 49.2 0.1 2.9e-12 47.3 0.1 1.9 1 1 0 1 1 1 1 SET domain zf-CHCC PF10276.9 KFM65223.1 - 0.61 10.2 6.3 0.63 10.1 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger domain zf-MYND PF01753.18 KFM65223.1 - 1.3 9.1 23.5 0.057 13.5 15.7 2.8 2 1 0 2 2 2 0 MYND finger Sin_N PF04801.13 KFM65226.1 - 4.1e-96 322.8 0.3 4.6e-96 322.7 0.3 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region Hydin_ADK PF17213.3 KFM65226.1 - 0.046 14.0 0.3 0.11 12.8 0.3 1.5 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain ADH_zinc_N PF00107.26 KFM65227.1 - 1.9e-20 73.1 0.2 3.7e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM65227.1 - 5.7e-12 45.5 0.1 2.5e-10 40.2 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFM65227.1 - 3e-10 41.3 0.0 5.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 KFM65227.1 - 0.079 12.0 0.2 0.15 11.1 0.2 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DPM3 PF08285.11 KFM65228.1 - 4.7e-29 100.4 0.7 5.2e-29 100.3 0.7 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Peptidase_M56 PF05569.11 KFM65228.1 - 0.0064 15.7 0.4 0.0074 15.5 0.4 1.1 1 0 0 1 1 1 1 BlaR1 peptidase M56 ABC_membrane PF00664.23 KFM65228.1 - 0.01 15.5 0.4 0.011 15.4 0.4 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region Methyltransf_31 PF13847.6 KFM65229.1 - 4.7e-10 39.5 0.1 5.3e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM65229.1 - 8.9e-05 23.2 0.0 0.00013 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM65229.1 - 0.0015 19.2 0.0 0.0061 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM65229.1 - 0.019 15.6 0.0 0.03 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFM65229.1 - 0.079 12.8 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFM65229.1 - 0.14 11.7 0.1 0.67 9.5 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase small domain DUF4347 PF14252.6 KFM65229.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) Pkinase PF00069.25 KFM65230.1 - 2.1e-22 79.7 0.0 2.4e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65230.1 - 4.5e-12 45.8 0.0 5e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_Rpa2_4 PF06883.12 KFM65230.1 - 0.12 12.4 0.0 7.8 6.6 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain Pkinase PF00069.25 KFM65231.1 - 1.4e-22 80.4 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65231.1 - 0.0031 16.8 0.1 0.005 16.2 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase P4Ha_N PF08336.11 KFM65232.1 - 1.9e-34 118.6 0.3 3e-34 117.9 0.3 1.3 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFM65232.1 - 2.4e-16 60.4 0.0 4.8e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 KFM65232.1 - 0.096 12.8 1.5 0.23 11.6 1.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_Tnp_Tc3_2 PF01498.18 KFM65233.1 - 2.4e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65233.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease AICARFT_IMPCHas PF01808.18 KFM65234.1 - 8.2e-90 301.2 0.0 1.1e-89 300.9 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KFM65234.1 - 7.9e-25 86.9 0.0 5.5e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain DPM2 PF07297.12 KFM65235.1 - 3.7e-13 49.6 3.1 3.9e-13 49.5 3.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KFM65235.1 - 0.027 14.4 0.7 0.03 14.2 0.7 1.1 1 0 0 1 1 1 0 PIG-P zf-H2C2_2 PF13465.6 KFM65236.1 - 4.9e-62 203.8 70.1 3.9e-08 33.4 1.5 9.3 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65236.1 - 1.6e-35 119.6 96.9 1.7e-05 25.0 8.6 10.3 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65236.1 - 2e-25 87.3 91.0 0.00041 21.0 1.0 10.2 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFM65236.1 - 3.2e-16 59.1 83.4 0.005 17.2 4.0 10.3 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65236.1 - 4.2e-08 33.0 83.4 0.0083 16.1 1.4 11.4 11 1 0 11 11 11 5 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM65236.1 - 1.2e-05 25.1 47.1 1.2 9.0 0.1 9.9 2 2 8 10 10 10 3 C2H2 type zinc-finger (1 copy) zf-CHCC PF10276.9 KFM65236.1 - 0.00011 22.2 8.6 34 4.6 0.0 7.7 9 0 0 9 9 9 0 Zinc-finger domain zf-DBF PF07535.12 KFM65236.1 - 0.00022 21.3 37.6 6 7.1 0.1 9.2 9 0 0 9 9 9 1 DBF zinc finger BolA PF01722.18 KFM65236.1 - 0.00081 19.6 20.4 0.65 10.3 2.5 4.9 1 1 4 5 5 5 4 BolA-like protein zf-C2H2_jaz PF12171.8 KFM65236.1 - 0.0012 19.0 64.3 0.12 12.7 4.4 9.5 6 2 3 9 9 9 3 Zinc-finger double-stranded RNA-binding zf-RRPl_C4 PF17026.5 KFM65236.1 - 0.004 17.2 31.1 2 8.5 3.2 4.5 1 1 3 4 4 4 2 Putative ribonucleoprotein zinc-finger pf C4 type ADK_lid PF05191.14 KFM65236.1 - 0.0075 16.2 29.1 0.79 9.8 0.9 6.3 3 2 3 7 7 7 3 Adenylate kinase, active site lid GAGA PF09237.11 KFM65236.1 - 0.009 15.8 24.9 0.4 10.5 0.2 6.7 1 1 8 9 9 9 2 GAGA factor zf-C2H2_2 PF12756.7 KFM65236.1 - 0.011 16.0 66.8 1.6 9.1 1.8 9.5 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) zf-HIT PF04438.16 KFM65236.1 - 0.013 15.4 37.4 10 6.1 0.1 9.0 9 0 0 9 9 9 0 HIT zinc finger zinc_ribbon_15 PF17032.5 KFM65236.1 - 0.12 13.2 31.7 1.9 9.3 2.4 5.1 1 1 5 6 6 6 0 zinc-ribbon family PqqA PF08042.11 KFM65236.1 - 0.31 11.1 3.7 4.9e+02 1.0 0.0 5.7 7 0 0 7 7 7 0 PqqA family Tox-HNH-HHH PF15637.6 KFM65236.1 - 0.54 10.4 6.5 6.8 6.9 0.3 3.4 1 1 3 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2HC_2 PF13913.6 KFM65236.1 - 0.77 9.7 45.6 0.26 11.2 0.6 8.0 9 0 0 9 9 8 0 zinc-finger of a C2HC-type zf-FPG_IleRS PF06827.14 KFM65236.1 - 0.86 9.5 27.4 35 4.4 0.1 7.6 8 0 0 8 8 8 0 Zinc finger found in FPG and IleRS HNH_5 PF14279.6 KFM65236.1 - 1.5 8.8 36.4 0.2 11.5 0.9 7.7 5 1 1 7 7 7 0 HNH endonuclease DUF5330 PF17264.2 KFM65236.1 - 4.1 7.5 16.3 1.5e+02 2.5 0.0 7.1 8 0 0 8 8 8 0 Family of unknown function (DUF5330) zf-Paramyx-P PF13008.7 KFM65236.1 - 5.6 6.5 24.4 80 2.8 0.1 7.7 8 0 0 8 8 8 0 Zinc-binding domain of Paramyxoviridae V protein FYVE PF01363.21 KFM65236.1 - 8.1 6.7 47.1 32 4.8 4.1 5.2 1 1 2 4 4 4 0 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 KFM65236.1 - 8.9 6.5 34.1 5.8 7.1 0.0 8.5 7 2 2 9 9 9 0 Sec23/Sec24 zinc finger Kinesin PF00225.23 KFM65237.1 - 1.1e-57 195.5 0.0 1.3e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM65237.1 - 1.3e-21 77.1 0.0 3.4e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 Microtubule binding Cupin_8 PF13621.6 KFM65238.1 - 2.7e-05 24.0 0.0 4.7e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KFM65238.1 - 0.003 18.0 1.3 0.031 14.7 0.0 2.3 2 1 1 3 3 3 1 JmjC domain, hydroxylase HTH_Tnp_Tc3_2 PF01498.18 KFM65240.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65240.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_22 PF13401.6 KFM65242.1 - 6.7e-06 26.4 0.0 1.4e-05 25.4 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KFM65242.1 - 0.00023 21.6 0.0 0.14 12.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KFM65242.1 - 0.00034 20.6 0.2 0.0015 18.5 0.2 2.0 1 1 0 1 1 1 1 NACHT domain DAP3 PF10236.9 KFM65242.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KFM65242.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KFM65242.1 - 0.018 14.6 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain RTP1_C1 PF10363.9 KFM65242.1 - 0.025 14.8 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 ATPase_2 PF01637.18 KFM65242.1 - 0.031 14.2 0.1 0.41 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KFM65242.1 - 0.043 14.0 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFM65242.1 - 0.045 12.9 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DPPIV_N PF00930.21 KFM65242.1 - 0.05 12.4 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region NB-ARC PF00931.22 KFM65242.1 - 0.055 12.6 0.0 0.32 10.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KFM65242.1 - 0.071 12.4 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KFM65242.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KFM65242.1 - 0.16 12.5 0.2 0.42 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain DDE_Tnp_1_7 PF13843.6 KFM65244.1 - 9.9e-78 261.9 4.1 1.3e-77 261.5 4.1 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM65244.1 - 0.0062 16.2 0.2 0.094 12.3 0.0 2.5 2 0 0 2 2 2 1 Transposase DDE domain Tnp_zf-ribbon_2 PF13842.6 KFM65244.1 - 0.022 15.5 9.9 0.065 14.0 9.9 1.9 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF4070 PF13282.6 KFM65244.1 - 0.14 12.2 4.1 0.17 12.0 2.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4070) HTH_Tnp_Tc3_2 PF01498.18 KFM65245.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65245.1 - 3.8e-13 49.4 0.0 7.2e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65245.1 - 1.6e-07 31.0 0.9 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65245.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65245.1 - 2 9.1 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM65246.1 - 2.1e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65246.1 - 2.3e-11 43.6 0.0 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65247.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65247.1 - 8.3e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65248.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65248.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM65249.1 - 1.9e-10 40.7 0.0 2.1e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease p450 PF00067.22 KFM65250.1 - 3.5e-69 233.7 0.0 4.5e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BBP1_N PF15271.6 KFM65250.1 - 0.1 13.4 0.2 0.17 12.7 0.2 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein BTB PF00651.31 KFM65252.1 - 2.4e-05 24.5 0.0 2.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain DUF2097 PF09870.9 KFM65252.1 - 0.094 12.9 0.0 0.29 11.4 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) p450 PF00067.22 KFM65253.1 - 2.7e-113 379.2 1.0 3.3e-113 378.9 1.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vg_Tdu PF07545.14 KFM65253.1 - 0.17 11.7 0.3 0.41 10.4 0.3 1.7 1 0 0 1 1 1 0 Vestigial/Tondu family p450 PF00067.22 KFM65254.1 - 2.8e-22 79.1 0.0 3.4e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 7tm_7 PF08395.12 KFM65254.1 - 0.0044 16.3 6.7 0.0069 15.6 6.7 1.4 1 0 0 1 1 1 1 7tm Chemosensory receptor Tyr_Deacylase PF02580.16 KFM65255.1 - 6.8e-44 149.9 0.0 7.8e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Phage_int_SAM_5 PF13102.6 KFM65255.1 - 0.084 13.2 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Phage integrase SAM-like domain Tyr_Deacylase PF02580.16 KFM65256.1 - 2e-51 174.3 0.0 2.2e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase TonB_2 PF13103.6 KFM65256.1 - 0.052 13.8 0.1 0.083 13.1 0.1 1.3 1 0 0 1 1 1 0 TonB C terminal LPAM_1 PF08139.12 KFM65260.1 - 0.11 13.1 3.5 0.16 12.6 3.5 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site PDGF PF00341.17 KFM65261.1 - 8.2e-12 45.3 4.9 1.1e-11 44.9 4.9 1.2 1 0 0 1 1 1 1 PDGF/VEGF domain RNA_pol_Rpb1_5 PF04998.17 KFM65262.1 - 1e-27 97.2 2.9 1.5e-27 96.7 2.9 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Tic110 PF16940.5 KFM65262.1 - 0.05 12.1 0.1 0.077 11.5 0.1 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter Raftlin PF15250.6 KFM65262.1 - 0.42 9.3 5.7 0.52 9.0 5.7 1.1 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.12 KFM65262.1 - 5.1 6.4 18.3 7 6.0 18.3 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 KFM65262.1 - 9.8 4.8 6.3 13 4.4 6.3 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpb1_2 PF00623.20 KFM65263.1 - 4e-67 225.6 0.0 7.7e-67 224.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 KFM65263.1 - 7.5e-65 219.0 0.2 2.6e-64 217.3 0.0 2.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 KFM65263.1 - 3.9e-34 117.9 1.9 2.6e-33 115.2 0.0 3.2 3 2 2 5 5 5 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFM65263.1 - 1.9e-22 79.3 0.0 7.9e-22 77.2 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 KFM65263.1 - 0.00099 18.5 5.9 0.00099 18.5 5.9 3.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 Peptidase_C34 PF05413.11 KFM65263.1 - 0.13 12.5 0.1 4 7.8 0.0 3.1 3 0 0 3 3 3 0 Putative closterovirus papain-like endopeptidase zf-TFIIB PF13453.6 KFM65263.1 - 0.18 11.1 0.4 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger IZUMO PF15005.6 KFM65263.1 - 7.9 7.0 10.1 23 5.5 2.6 2.8 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated RNA_pol_Rpb1_1 PF04997.12 KFM65264.1 - 7.1e-20 71.6 0.0 7.1e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Stathmin PF00836.19 KFM65265.1 - 3e-39 134.1 20.0 3.5e-39 133.9 20.0 1.0 1 0 0 1 1 1 1 Stathmin family DUF2284 PF10050.9 KFM65265.1 - 0.091 12.5 4.7 1.5 8.5 4.7 2.0 1 1 0 1 1 1 0 Predicted metal-binding protein (DUF2284) HSP70 PF00012.20 KFM65265.1 - 0.18 9.9 16.9 0.22 9.7 16.9 1.0 1 0 0 1 1 1 0 Hsp70 protein Exonuc_VII_L PF02601.15 KFM65265.1 - 0.3 10.6 11.9 0.36 10.4 11.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2852 PF11014.8 KFM65265.1 - 0.48 10.6 8.2 0.68 10.1 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Spc7 PF08317.11 KFM65265.1 - 0.92 8.3 20.9 1.2 7.9 20.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Pannexin_like PF12534.8 KFM65265.1 - 1 8.4 10.0 1.3 8.1 10.0 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 AAA_11 PF13086.6 KFM65265.1 - 1.6 8.5 13.3 1.9 8.2 13.3 1.1 1 0 0 1 1 1 0 AAA domain ALMT PF11744.8 KFM65265.1 - 5.1 5.8 13.4 6 5.6 13.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 KFM65265.1 - 6.1 4.6 12.9 6.9 4.5 12.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDE_Tnp_1_7 PF13843.6 KFM65266.1 - 2.2e-73 247.6 2.6 2.6e-73 247.3 2.6 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM65266.1 - 5.5e-06 27.1 11.1 1.1e-05 26.2 11.1 1.5 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon DDE_Tnp_1 PF01609.21 KFM65266.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.7 1 1 0 1 1 1 0 Transposase DDE domain FBA_3 PF08268.12 KFM65266.1 - 0.08 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 F-box associated domain HTH_Tnp_Tc3_2 PF01498.18 KFM65267.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65267.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65267.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65267.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65267.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Pkinase_Tyr PF07714.17 KFM65268.1 - 1.3e-97 326.1 0.0 2.1e-97 325.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM65268.1 - 1.5e-47 162.2 0.0 3.4e-47 161.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFM65268.1 - 5.6e-24 84.0 0.0 1.9e-23 82.4 0.0 2.0 1 0 0 1 1 1 1 SH2 domain F_actin_bind PF08919.10 KFM65268.1 - 2.6e-16 59.7 2.3 1.1e-15 57.7 2.3 2.2 1 0 0 1 1 1 1 F-actin binding SH3_1 PF00018.28 KFM65268.1 - 1e-10 41.1 0.0 2.3e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM65268.1 - 3.1e-09 36.6 0.1 6.2e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM65268.1 - 1.7e-07 30.8 0.0 3.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFM65268.1 - 0.0011 19.2 0.6 0.0028 17.9 0.6 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain APH PF01636.23 KFM65268.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ArsR PF09824.9 KFM65268.1 - 0.033 13.8 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 ArsR transcriptional regulator Toxin-deaminase PF14424.6 KFM65268.1 - 0.58 10.3 5.9 5 7.2 0.1 3.1 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases Ig_3 PF13927.6 KFM65269.1 - 4.9e-26 91.1 0.2 1.9e-12 47.6 0.0 2.6 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM65269.1 - 7.2e-24 83.7 0.0 9e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM65269.1 - 1.1e-15 57.7 0.0 3.4e-09 36.9 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM65269.1 - 1.4e-13 50.8 0.0 8.8e-06 25.8 0.0 3.3 2 2 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM65269.1 - 1.7e-12 47.4 0.1 1.8e-06 28.1 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFM65269.1 - 4.2e-05 23.5 0.0 0.021 14.8 0.0 2.5 2 0 0 2 2 2 2 C17orf99 Ig domain Ig_6 PF18452.1 KFM65269.1 - 0.01 15.4 0.0 0.49 10.0 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain PNK3P PF08645.11 KFM65269.1 - 0.022 14.5 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase C2-set_2 PF08205.12 KFM65269.1 - 0.047 13.8 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KFM65269.1 - 0.1 12.6 0.0 0.49 10.4 0.0 2.2 1 1 1 2 2 2 0 CD47 immunoglobulin-like domain Ntox4 PF15541.6 KFM65269.1 - 0.17 12.3 0.0 22 5.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial toxin 4 MG3 PF17791.1 KFM65270.1 - 1.9e-19 69.7 0.0 1.9e-18 66.5 0.0 2.3 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG4 PF17789.1 KFM65270.1 - 5.6e-09 36.0 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Macroglobulin domain MG4 PI-PLC-X PF00388.19 KFM65271.1 - 4.6e-61 204.6 0.0 7.1e-61 204.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.11 KFM65271.1 - 2.5e-12 47.1 0.7 7.3e-12 45.6 0.7 1.8 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_14 PF17787.1 KFM65271.1 - 7.9e-06 25.8 0.2 2.3e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 PH domain ParD_like PF11903.8 KFM65271.1 - 0.036 14.1 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system PI-PLC-Y PF00387.19 KFM65272.1 - 3.1e-44 150.0 0.3 3.1e-44 150.0 0.3 3.1 3 2 1 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF1154 PF06631.11 KFM65272.1 - 6.5e-09 35.7 10.7 6.5e-09 35.7 10.7 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF1154) C2 PF00168.30 KFM65272.1 - 6.3e-07 29.6 0.0 1.7e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain DDE_3 PF13358.6 KFM65273.1 - 1.7e-10 40.9 0.0 2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM65274.1 - 6.8e-15 55.1 0.0 9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SAP PF02037.27 KFM65276.1 - 5.5e-13 48.3 1.9 5.3e-12 45.2 0.9 2.4 2 0 0 2 2 2 1 SAP domain RRM_1 PF00076.22 KFM65276.1 - 2.9e-12 46.2 0.0 5.8e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM65276.1 - 0.0049 16.5 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HeH PF12949.7 KFM65276.1 - 0.051 13.3 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 HeH/LEM domain zf-IS66 PF13005.7 KFM65276.1 - 2.8 8.4 4.1 20 5.7 0.6 3.2 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 SH2_2 PF14633.6 KFM65277.1 - 1.8e-70 236.7 1.4 1.8e-70 236.7 1.4 2.2 2 0 0 2 2 1 1 SH2 domain YqgF PF14639.6 KFM65277.1 - 2.2e-45 154.1 2.6 2.4e-45 154.0 0.0 2.3 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KFM65277.1 - 1.7e-39 134.4 0.0 3.2e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 KFM65277.1 - 2e-23 83.0 0.5 2e-23 83.0 0.5 2.1 2 0 0 2 2 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KFM65277.1 - 7.4e-16 58.5 39.7 7.4e-16 58.5 39.7 5.7 3 1 2 5 5 2 1 Acidic N-terminal SPT6 S1 PF00575.23 KFM65277.1 - 2.1e-11 44.0 0.0 1e-10 41.8 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain Tex_N PF09371.10 KFM65277.1 - 1.7e-08 34.3 1.2 0.004 16.9 0.1 3.3 3 1 0 3 3 3 2 Tex-like protein N-terminal domain SH2 PF00017.24 KFM65277.1 - 1e-07 32.0 0.0 5.5e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 SH2 domain HHH_9 PF17674.1 KFM65277.1 - 2e-05 25.4 0.2 2e-05 25.4 0.2 3.0 3 0 0 3 3 1 1 HHH domain HHH_3 PF12836.7 KFM65277.1 - 0.00056 20.1 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 KFM65277.1 - 0.066 13.7 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 Tex protein YqgF-like domain DnaJ PF00226.31 KFM65278.1 - 3.7e-21 75.0 0.8 7.6e-21 74.0 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain P120R PF08062.11 KFM65278.1 - 0.065 13.6 0.4 0.29 11.5 0.4 2.1 1 0 0 1 1 1 0 P120R (NUC006) repeat RPT PF13446.6 KFM65278.1 - 0.14 12.1 0.0 0.7 9.9 0.0 1.9 1 1 1 2 2 2 0 A repeated domain in UCH-protein DnaJ PF00226.31 KFM65280.1 - 1.2e-22 79.8 1.4 3.2e-22 78.4 1.4 1.8 1 0 0 1 1 1 1 DnaJ domain Mod_r PF07200.13 KFM65281.1 - 4.7e-34 117.6 19.3 5.7e-34 117.3 19.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF4883 PF16224.5 KFM65281.1 - 4.9 7.4 6.8 2.7 8.2 0.7 2.1 1 1 1 2 2 2 0 DOmain of unknown function (DUF4883) LSM PF01423.22 KFM65282.1 - 1.1e-15 57.0 0.2 1.4e-15 56.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain DDE_3 PF13358.6 KFM65283.1 - 0.00063 19.5 0.0 0.00075 19.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM65285.1 - 2.8e-10 40.2 0.0 4.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) PepX_C PF08530.10 KFM65285.1 - 0.14 12.0 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Cadherin PF00028.17 KFM65286.1 - 9.6e-172 558.0 25.3 1.3e-22 80.0 0.0 9.8 10 0 0 10 10 10 9 Cadherin domain Cadherin_3 PF16184.5 KFM65286.1 - 8.2e-18 64.4 18.3 0.00063 19.7 0.0 9.1 9 0 0 9 9 9 6 Cadherin-like Cadherin_2 PF08266.12 KFM65286.1 - 4.5e-11 42.4 0.0 0.31 10.9 0.0 8.2 9 0 0 9 9 9 3 Cadherin-like Cadherin_4 PF17803.1 KFM65286.1 - 7.3e-05 23.3 50.2 0.21 12.2 0.2 8.7 8 0 0 8 8 8 6 Bacterial cadherin-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM65287.1 - 5.2e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65287.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65287.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65287.1 - 0.0027 17.5 0.6 0.0078 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65287.1 - 2.3 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain GP120 PF00516.18 KFM65290.1 - 0.058 12.0 0.0 0.06 11.9 0.0 1.0 1 0 0 1 1 1 0 Envelope glycoprotein GP120 PDEase_II PF02112.15 KFM65290.1 - 0.067 12.3 0.2 0.067 12.3 0.2 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KFM65290.1 - 0.076 12.5 0.2 0.087 12.3 0.2 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Use1 PF09753.9 KFM65291.1 - 8.4e-76 255.0 12.0 9.5e-76 254.8 12.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Rhabdo_glycop PF00974.18 KFM65291.1 - 0.0029 16.1 1.0 0.0037 15.8 1.0 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein CrgA PF06781.12 KFM65291.1 - 0.01 15.9 0.2 0.025 14.6 0.2 1.6 1 0 0 1 1 1 0 Cell division protein CrgA TFIIS_M PF07500.14 KFM65291.1 - 0.014 15.9 5.5 0.046 14.2 1.0 2.8 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS), central domain TBCA PF02970.16 KFM65291.1 - 0.05 13.9 9.2 0.085 13.2 3.2 2.9 2 1 1 3 3 3 0 Tubulin binding cofactor A MCU PF04678.13 KFM65291.1 - 0.14 12.3 9.1 0.089 12.9 4.9 2.3 1 1 0 2 2 2 0 Mitochondrial calcium uniporter XhlA PF10779.9 KFM65291.1 - 0.35 11.1 4.2 0.42 10.8 0.1 2.9 3 0 0 3 3 3 0 Haemolysin XhlA HTH_Tnp_Tc3_2 PF01498.18 KFM65293.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65293.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65293.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65293.1 - 0.0023 17.7 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65293.1 - 1.8 9.3 15.7 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain TFIID_30kDa PF03540.13 KFM65294.1 - 5.5e-24 83.9 0.1 8.7e-24 83.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KFM65294.1 - 3.4e-05 23.8 0.0 0.00029 20.8 0.0 2.1 1 1 0 1 1 1 1 Bromodomain associated TFIID_30kDa PF03540.13 KFM65295.1 - 2.8e-24 84.8 0.3 4.3e-24 84.2 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KFM65295.1 - 0.00015 21.7 0.0 0.00077 19.4 0.0 1.9 1 1 0 1 1 1 1 Bromodomain associated TAF4 PF05236.14 KFM65295.1 - 0.0015 18.3 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CBFD_NFYB_HMF PF00808.23 KFM65295.1 - 0.065 13.5 0.0 0.58 10.5 0.0 2.2 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFM65295.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit LEM PF03020.15 KFM65295.1 - 0.22 11.1 0.8 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 LEM domain VPS13_mid_rpt PF16910.5 KFM65296.1 - 8.2e-69 231.6 1.1 1.7e-67 227.3 0.4 2.2 2 0 0 2 2 2 1 Repeating coiled region of VPS13 VPS13 PF16908.5 KFM65296.1 - 1.6e-35 123.0 1.3 6e-34 117.9 0.2 3.0 3 1 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal zf_C2HC_14 PF18574.1 KFM65296.1 - 1.3 8.9 3.4 2.7 7.9 3.4 1.5 1 0 0 1 1 1 0 C2HC Zing finger domain Chorein_N PF12624.7 KFM65297.1 - 2.4e-36 124.3 0.0 3.1e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 PEP_hydrolase PF09370.10 KFM65297.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like HTH_Tnp_Tc3_2 PF01498.18 KFM65300.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65300.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MADF_DNA_bdg PF10545.9 KFM65301.1 - 4.3e-17 62.2 2.1 8.1e-17 61.3 2.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 KFM65301.1 - 0.033 14.0 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 BESS motif Myb_DNA-binding PF00249.31 KFM65301.1 - 0.047 13.9 0.5 0.098 12.9 0.5 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain zf-RING_5 PF14634.6 KFM65302.1 - 5.7e-06 26.2 19.5 9.7e-06 25.4 19.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM65302.1 - 0.061 13.2 16.6 0.1 12.5 16.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SRF-TF PF00319.18 KFM65302.1 - 0.082 12.4 1.0 0.52 9.8 0.1 2.3 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Prok-RING_4 PF14447.6 KFM65302.1 - 0.95 9.4 17.0 7.5 6.5 16.7 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 GGACT PF06094.12 KFM65303.1 - 2.4e-19 70.1 0.0 3.2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Mob1_phocein PF03637.17 KFM65304.1 - 1.4e-74 249.7 0.1 1.6e-74 249.5 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family CH PF00307.31 KFM65305.1 - 4.8e-15 55.7 0.0 5.7e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM65305.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.4 1 1 0 1 1 1 0 CAMSAP CH domain CH PF00307.31 KFM65306.1 - 5.9e-16 58.6 0.6 7.4e-16 58.3 0.6 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF957 PF06117.11 KFM65306.1 - 0.00057 19.4 0.5 0.001 18.6 0.5 1.4 1 0 0 1 1 1 1 Enterobacterial protein of unknown function (DUF957) WASH-7_N PF14745.6 KFM65306.1 - 0.016 13.7 0.1 0.017 13.7 0.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal TPD52 PF04201.15 KFM65307.1 - 4.5e-36 123.9 10.4 5.3e-36 123.7 10.4 1.1 1 0 0 1 1 1 1 Tumour protein D52 family NB-LRR PF12061.8 KFM65307.1 - 0.009 15.4 0.2 0.011 15.0 0.2 1.1 1 0 0 1 1 1 1 Late blight resistance protein R1 ApoO PF09769.9 KFM65307.1 - 0.028 14.4 1.9 0.36 10.8 1.9 2.2 1 1 0 1 1 1 0 Apolipoprotein O Fib_alpha PF08702.10 KFM65307.1 - 0.036 14.2 9.1 0.16 12.2 1.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 KFM65307.1 - 0.037 14.3 7.3 1 9.7 1.5 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF1835 PF08874.10 KFM65307.1 - 0.12 12.6 2.8 0.2 11.9 2.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1835) PIN_8 PF18476.1 KFM65307.1 - 0.19 11.5 5.6 0.26 11.1 5.6 1.3 1 0 0 1 1 1 0 PIN like domain OmpH PF03938.14 KFM65307.1 - 0.23 11.8 11.1 0.58 10.5 10.9 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HisKA_3 PF07730.13 KFM65307.1 - 0.25 11.9 1.0 9.6 6.8 0.1 2.5 2 0 0 2 2 2 0 Histidine kinase COG5 PF10392.9 KFM65307.1 - 0.35 11.1 4.1 0.57 10.4 0.6 2.0 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DUF883 PF05957.13 KFM65307.1 - 0.62 10.7 5.9 9.5 6.9 0.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mod_r PF07200.13 KFM65307.1 - 0.95 9.6 11.3 1.6 8.8 9.7 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1451 PF07295.11 KFM65307.1 - 2.2 8.3 7.3 3.7 7.6 2.0 1.9 1 1 2 3 3 3 0 Zinc-ribbon containing domain Prefoldin_2 PF01920.20 KFM65307.1 - 5 7.1 13.6 0.45 10.5 4.4 2.6 1 1 1 2 2 2 0 Prefoldin subunit ABC_membrane PF00664.23 KFM65308.1 - 8.5e-10 38.7 1.8 9.9e-10 38.5 1.8 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFM65309.1 - 7.1e-36 123.7 0.0 5.3e-35 120.9 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KFM65309.1 - 1.1e-15 58.0 1.3 1.5e-15 57.6 1.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KFM65309.1 - 1.1e-09 38.1 0.0 2.3e-07 30.5 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KFM65309.1 - 0.00072 19.4 0.2 0.0019 18.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 KFM65309.1 - 0.00082 19.8 0.1 0.0027 18.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KFM65309.1 - 0.001 18.3 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KFM65309.1 - 0.0016 18.5 0.0 0.011 15.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM65309.1 - 0.0022 18.2 0.1 0.028 14.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 KFM65309.1 - 0.0023 17.2 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit RsgA_GTPase PF03193.16 KFM65309.1 - 0.0034 17.3 0.1 0.011 15.7 0.0 1.9 3 0 0 3 3 2 1 RsgA GTPase AAA_29 PF13555.6 KFM65309.1 - 0.0036 17.0 0.2 0.0085 15.8 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 KFM65309.1 - 0.01 16.0 0.2 0.042 14.0 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 KFM65309.1 - 0.015 14.8 0.0 0.22 11.0 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_30 PF13604.6 KFM65309.1 - 0.029 14.1 0.0 0.087 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFM65309.1 - 0.038 14.4 0.1 0.45 10.9 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KFM65309.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KFM65309.1 - 0.062 13.8 0.0 0.25 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFM65309.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KFM65309.1 - 0.1 11.6 0.3 0.21 10.5 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 KFM65309.1 - 0.13 12.0 0.2 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Sugar_tr PF00083.24 KFM65310.1 - 3.7e-08 32.7 0.1 5.1e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM65310.1 - 4.1e-08 32.5 6.4 6.8e-08 31.8 6.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFM65310.1 - 6.8e-06 24.9 3.7 6.8e-06 24.9 3.7 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 KFM65310.1 - 0.0024 16.4 0.4 0.0038 15.7 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 KFM65310.1 - 0.0036 15.6 0.7 0.0052 15.1 0.7 1.1 1 0 0 1 1 1 1 BT1 family Sugar_tr PF00083.24 KFM65311.1 - 1.6e-17 63.5 5.6 2.1e-17 63.1 5.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM65311.1 - 3.6e-12 45.9 17.8 2.7e-09 36.4 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFM65312.1 - 1.5e-10 40.6 0.9 1.8e-10 40.3 0.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM65312.1 - 1.7e-06 27.2 0.0 2.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KFM65312.1 - 0.0002 20.1 0.2 0.0002 20.1 0.2 1.5 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KFM65312.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 0 MFS_1 like family MFS_1 PF07690.16 KFM65313.1 - 1.9e-06 27.1 5.3 1.9e-06 27.0 5.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM65313.1 - 4e-05 22.7 3.6 8.3e-05 21.6 3.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFM65313.1 - 0.015 14.2 2.2 0.018 13.9 2.2 1.0 1 0 0 1 1 1 0 MFS_1 like family Leukocidin PF07968.12 KFM65314.1 - 0.008 16.1 0.1 0.0082 16.1 0.1 1.0 1 0 0 1 1 1 1 Leukocidin/Hemolysin toxin family Sugar_tr PF00083.24 KFM65316.1 - 5e-19 68.5 15.3 7.3e-19 68.0 15.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM65316.1 - 1.7e-11 43.7 18.5 4.5e-06 25.8 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Wzy_C PF04932.15 KFM65316.1 - 0.055 13.1 1.9 0.22 11.1 0.0 2.7 2 1 1 3 3 3 0 O-Antigen ligase DUF2575 PF10837.8 KFM65316.1 - 0.091 13.1 0.2 0.34 11.2 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Peptidase_M14 PF00246.24 KFM65318.1 - 1.9e-71 241.2 0.0 2.7e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFM65318.1 - 1.9e-12 47.3 0.0 3.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFM65318.1 - 0.022 14.7 0.1 0.061 13.3 0.1 1.7 1 1 0 1 1 1 0 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KFM65318.1 - 0.088 11.9 0.0 0.32 10.0 0.0 1.9 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Lig_chan PF00060.26 KFM65319.1 - 1.6e-07 31.3 2.2 5.2e-07 29.6 2.2 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 KFM65319.1 - 5.4e-06 26.0 0.0 7e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 KFM65319.1 - 0.0025 18.0 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site HTH_Tnp_Tc3_2 PF01498.18 KFM65320.1 - 4.1e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65320.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65320.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65320.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65320.1 - 2 9.1 15.4 0.11 13.1 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain p450 PF00067.22 KFM65322.1 - 4.3e-86 289.5 0.1 5.2e-86 289.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM65323.1 - 2.6e-110 369.3 0.1 3.3e-110 369.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_Tnp_Tc3_2 PF01498.18 KFM65324.1 - 3.6e-16 59.2 3.4 5.2e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65324.1 - 5.5e-13 48.9 0.0 9.6e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65324.1 - 1.2e-07 31.3 0.9 6.6e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65324.1 - 0.0018 18.0 0.6 0.007 16.1 0.6 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM65324.1 - 0.024 14.8 0.4 0.084 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM65324.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain adh_short PF00106.25 KFM65325.1 - 1.6e-41 142.0 0.1 1.9e-41 141.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM65325.1 - 1.7e-38 132.5 0.0 2e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM65325.1 - 2.9e-08 33.8 0.3 4.9e-08 33.1 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM65325.1 - 0.00043 19.8 0.2 0.001 18.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFM65325.1 - 0.039 14.2 0.1 0.085 13.1 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KFM65326.1 - 1.4e-39 135.6 0.1 1.6e-39 135.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM65326.1 - 2.6e-33 115.5 0.0 3.3e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM65326.1 - 2.2e-07 31.0 0.3 5.4e-07 29.7 0.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM65326.1 - 0.00072 19.1 0.1 0.002 17.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFM65326.1 - 0.0091 15.2 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFM65326.1 - 0.023 13.9 0.2 0.049 12.8 0.2 1.7 1 1 0 1 1 1 0 Male sterility protein GDP_Man_Dehyd PF16363.5 KFM65326.1 - 0.043 13.2 0.1 0.076 12.4 0.1 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KFM65327.1 - 9e-24 84.0 0.1 1e-23 83.9 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM65327.1 - 3.4e-18 66.1 0.0 4.2e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM65327.1 - 6.2e-11 42.5 0.0 9.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM65327.1 - 1e-05 25.1 0.1 1.8e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFM65327.1 - 1.6e-05 25.2 0.2 2e-05 24.8 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KFM65327.1 - 2.2e-05 23.6 0.7 3.2e-05 23.1 0.7 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PrpR_N PF06506.11 KFM65327.1 - 0.0033 17.0 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Propionate catabolism activator GDP_Man_Dehyd PF16363.5 KFM65327.1 - 0.0057 16.1 0.1 0.015 14.8 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFM65327.1 - 0.044 12.9 0.2 0.47 9.6 0.2 2.0 1 1 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.17 KFM65327.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.6 KFM65328.1 - 8.1e-18 64.8 0.0 9.5e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM65328.1 - 4.2e-17 62.2 0.0 5.7e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase rpo132 PF12415.8 KFM65328.1 - 0.12 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase Ras PF00071.22 KFM65329.1 - 5e-13 49.0 0.1 6.9e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFM65329.1 - 0.0084 15.6 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM65329.1 - 0.03 13.9 0.1 0.047 13.2 0.1 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Phage_integrase PF00589.22 KFM65329.1 - 0.095 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family HNF-1_N PF04814.13 KFM65329.1 - 0.91 10.1 0.0 0.91 10.1 0.0 2.1 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Helitron_like_N PF14214.6 KFM65330.1 - 9.4e-21 74.9 0.6 1.2e-20 74.6 0.6 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SPARC_Ca_bdg PF10591.9 KFM65331.1 - 5.4e-38 129.8 4.1 1.5e-37 128.4 4.1 1.8 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region FOLN PF09289.10 KFM65331.1 - 0.0013 18.9 4.4 0.0013 18.9 4.4 2.6 3 0 0 3 3 3 1 Follistatin/Osteonectin-like EGF domain Kazal_2 PF07648.15 KFM65331.1 - 0.0029 17.7 10.8 0.0029 17.7 10.8 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain YbgT_YccB PF08173.11 KFM65335.1 - 0.11 12.7 0.7 0.16 12.2 0.7 1.2 1 0 0 1 1 1 0 Membrane bound YbgT-like protein Amino_oxidase PF01593.24 KFM65336.1 - 7.7e-15 55.1 0.0 8.1e-11 41.9 0.0 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM65336.1 - 4.1e-13 49.4 0.0 8.2e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM65336.1 - 0.00082 19.0 0.3 0.43 10.1 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFM65336.1 - 0.0058 16.6 0.0 0.98 9.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KFM65336.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFM65336.1 - 0.082 13.5 1.4 20 5.8 0.0 3.0 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase SH3_10 PF17902.1 KFM65336.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Pyr_redox_2 PF07992.14 KFM65336.1 - 0.19 11.0 0.0 11 5.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glutaredoxin PF00462.24 KFM65338.1 - 1.8e-17 63.3 0.1 2.8e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KFM65338.1 - 0.0007 20.0 0.7 0.0017 18.8 0.6 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KFM65338.1 - 0.016 15.2 0.2 0.049 13.7 0.2 1.8 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.6 KFM65338.1 - 0.04 14.1 0.4 0.1 12.8 0.4 1.7 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.6 KFM65338.1 - 0.077 13.2 0.7 15 5.7 0.0 2.2 1 1 0 2 2 2 0 Thioredoxin RFX5_N PF18326.1 KFM65338.1 - 0.092 12.5 1.2 0.2 11.4 0.6 1.9 2 0 0 2 2 2 0 RFX5 N-terminal domain RNA_pol_Rpb2_4 PF04566.13 KFM65338.1 - 0.099 13.0 0.0 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 cNMP_binding PF00027.29 KFM65339.1 - 2.7e-19 69.0 0.0 4.1e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Hpt PF01627.23 KFM65339.1 - 0.0034 17.6 0.3 0.0064 16.7 0.3 1.4 1 0 0 1 1 1 1 Hpt domain SlyX PF04102.12 KFM65339.1 - 0.012 16.2 1.9 0.026 15.1 1.9 1.5 1 0 0 1 1 1 0 SlyX FPP PF05911.11 KFM65339.1 - 0.046 11.9 4.5 0.062 11.5 4.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4472 PF14739.6 KFM65339.1 - 0.052 14.3 2.9 0.089 13.5 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Cnn_1N PF07989.11 KFM65339.1 - 0.16 12.1 4.1 0.34 11.1 4.1 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 MPS2 PF17060.5 KFM65339.1 - 0.3 10.3 3.4 0.58 9.4 3.4 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF3450 PF11932.8 KFM65339.1 - 0.33 10.2 2.9 0.48 9.7 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 KFM65339.1 - 0.33 11.4 4.7 0.21 12.0 2.2 2.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 KFM65340.1 - 1e-70 238.1 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65340.1 - 1.7e-35 122.5 0.0 2.3e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KFM65340.1 - 0.0033 16.5 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KFM65340.1 - 0.0033 16.8 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFM65340.1 - 0.016 15.2 0.0 0.044 13.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Comm PF15957.5 KFM65341.1 - 0.56 10.6 4.1 0.54 10.6 4.1 1.1 1 0 0 1 1 1 0 Commissureless Pkinase_Tyr PF07714.17 KFM65342.1 - 1.9e-91 305.9 0.0 2.4e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM65342.1 - 3.6e-49 167.5 0.0 7.7e-49 166.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 KFM65342.1 - 7.4e-18 64.4 0.0 2e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFM65342.1 - 3.1e-07 30.2 0.0 6.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM65342.1 - 7.5e-06 25.5 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Kinase-like PF14531.6 KFM65342.1 - 0.00029 20.3 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFM65342.1 - 0.0056 16.3 0.1 0.017 14.8 0.1 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFM65342.1 - 0.01 15.7 0.1 0.2 11.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH3_2 PF07653.17 KFM65342.1 - 0.032 13.9 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain Haspin_kinase PF12330.8 KFM65342.1 - 0.051 12.5 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF659 PF04937.15 KFM65343.1 - 4e-07 30.0 1.0 0.0069 16.3 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KFM65343.1 - 9.4e-07 28.5 0.0 2.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Propep_M14 PF02244.16 KFM65343.1 - 2.4 8.6 5.2 3.8 8.0 0.7 3.1 4 0 0 4 4 4 0 Carboxypeptidase activation peptide HTH_Tnp_Tc3_2 PF01498.18 KFM65344.1 - 5.1e-16 58.7 3.5 6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65344.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65344.1 - 2.1e-07 30.6 1.1 7.3e-07 28.9 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65344.1 - 0.0062 16.3 0.6 0.018 14.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65344.1 - 3.5 8.3 15.9 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Retrotran_gag_2 PF14223.6 KFM65345.1 - 9.1e-10 38.3 4.2 9.1e-10 38.3 4.2 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KFM65345.1 - 4.4e-05 23.3 0.0 0.00016 21.4 0.0 2.0 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 KFM65345.1 - 0.083 13.0 0.6 0.17 12.0 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Pkinase_Tyr PF07714.17 KFM65346.1 - 1.5e-95 319.4 0.0 1.9e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM65346.1 - 3.6e-46 157.7 0.0 4.8e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFM65346.1 - 2.6e-14 53.1 0.0 4.9e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 KFM65346.1 - 0.00047 19.2 0.0 0.0014 17.7 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM65346.1 - 0.0019 18.2 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM65346.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VWC PF00093.18 KFM65348.1 - 1.6e-12 47.5 38.1 5.9e-07 29.7 14.8 2.2 2 0 0 2 2 2 2 von Willebrand factor type C domain TerY_C PF15616.6 KFM65348.1 - 5.3 7.2 24.4 0.16 12.1 9.4 2.4 2 0 0 2 2 2 0 TerY-C metal binding domain TTRAP PF14203.6 KFM65350.1 - 0.0057 16.6 0.9 0.014 15.4 0.9 1.7 1 0 0 1 1 1 1 Putative tranposon-transfer assisting protein BRK PF07533.16 KFM65350.1 - 0.13 11.9 0.1 0.32 10.7 0.0 1.8 1 1 0 1 1 1 0 BRK domain BRICHOS PF04089.14 KFM65352.1 - 1.4e-10 41.2 0.0 2.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 BRICHOS domain DUF229 PF02995.17 KFM65353.1 - 4.4e-68 230.1 0.1 5.2e-68 229.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 KFM65353.1 - 0.011 15.1 0.0 0.028 13.8 0.0 1.6 1 1 0 1 1 1 0 Sulfatase DUF1501 PF07394.12 KFM65353.1 - 0.018 14.1 0.0 3.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 KFM65353.1 - 0.17 11.4 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase HTH_Tnp_Tc3_2 PF01498.18 KFM65355.1 - 1.9e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65355.1 - 7.6e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PDEase_I PF00233.19 KFM65357.1 - 4.5e-83 278.6 0.7 6.7e-83 278.1 0.1 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFM65357.1 - 1.7e-06 28.7 0.0 1.4e-05 25.7 0.0 2.4 1 1 0 1 1 1 1 GAF domain HD PF01966.22 KFM65357.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 HD domain GAF_3 PF13492.6 KFM65357.1 - 0.12 12.8 0.0 7.4 6.9 0.0 2.5 2 0 0 2 2 2 0 GAF domain adh_short_C2 PF13561.6 KFM65358.1 - 2.9e-61 207.0 0.6 3.6e-61 206.7 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM65358.1 - 1.2e-54 184.8 3.0 1.5e-54 184.4 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM65358.1 - 1.1e-13 51.5 0.3 1.5e-13 51.1 0.3 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFM65358.1 - 0.05 13.5 0.2 2.6 7.9 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 KFM65358.1 - 0.056 13.2 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.6 KFM65359.1 - 9.2e-63 211.9 0.2 1.1e-62 211.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM65359.1 - 4.4e-54 182.9 0.6 5.6e-54 182.6 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM65359.1 - 4.5e-14 52.7 0.2 5.9e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 KR domain TMEM215 PF15746.5 KFM65359.1 - 0.11 11.9 2.0 5.6 6.4 0.1 2.3 2 1 0 2 2 2 0 TMEM215 family Arena_RNA_pol PF06317.11 KFM65359.1 - 0.14 9.3 0.0 0.18 8.9 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase FYRN PF05964.14 KFM65360.1 - 1.3e-14 53.8 0.2 1.3e-14 53.8 0.2 2.5 2 0 0 2 2 2 1 F/Y-rich N-terminus zf-CXXC PF02008.20 KFM65360.1 - 4.5e-13 49.0 16.2 4.5e-13 49.0 16.2 6.7 6 0 0 6 6 6 1 CXXC zinc finger domain PHD PF00628.29 KFM65360.1 - 4.2e-11 42.6 60.1 2.7e-06 27.1 13.3 8.0 6 1 2 8 8 8 4 PHD-finger zf-HC5HC2H PF13771.6 KFM65360.1 - 4.8e-11 42.8 5.7 4.8e-11 42.8 5.7 7.0 6 1 1 7 7 7 1 PHD-like zinc-binding domain zf-C4 PF00105.18 KFM65360.1 - 0.0012 19.3 9.3 0.0012 19.3 9.3 5.7 5 0 0 5 5 5 1 Zinc finger, C4 type (two domains) Ion_trans PF00520.31 KFM65361.1 - 2.9e-10 39.8 4.7 3.8e-10 39.4 4.7 1.1 1 0 0 1 1 1 1 Ion transport protein SPOC PF07744.13 KFM65362.1 - 1.5e-07 31.4 0.0 1.7e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 SPOC domain HTH_Tnp_Tc3_2 PF01498.18 KFM65363.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65363.1 - 8.3e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Dynamin_M PF01031.20 KFM65364.1 - 0.009 15.3 0.4 0.011 15.0 0.4 1.0 1 0 0 1 1 1 1 Dynamin central region XhlA PF10779.9 KFM65364.1 - 0.062 13.5 0.5 0.098 12.9 0.5 1.3 1 0 0 1 1 1 0 Haemolysin XhlA PQ-loop PF04193.14 KFM65366.1 - 0.12 12.1 3.1 0.52 10.1 0.0 2.0 1 1 1 2 2 2 0 PQ loop repeat Ras PF00071.22 KFM65367.1 - 1.7e-45 154.5 0.6 1.9e-45 154.4 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM65367.1 - 2e-35 121.6 0.2 2.4e-35 121.4 0.2 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM65367.1 - 1.3e-11 44.3 0.1 1.5e-11 44.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM65367.1 - 1.3e-07 31.7 0.0 1.7e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFM65367.1 - 1.6e-05 24.6 0.2 4.3e-05 23.2 0.1 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFM65367.1 - 0.0012 18.3 0.1 0.0015 18.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFM65367.1 - 0.0018 18.2 1.6 0.71 9.8 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KFM65367.1 - 0.0044 16.8 0.1 0.0051 16.6 0.1 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KFM65367.1 - 0.0072 16.1 1.9 0.07 12.9 0.2 2.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 KFM65367.1 - 0.011 15.2 0.2 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 KFM65367.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 KFM65367.1 - 0.1 12.7 0.3 0.45 10.6 0.3 2.1 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain UCH PF00443.29 KFM65368.1 - 2.7e-48 164.7 1.5 3.4e-48 164.4 1.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM65368.1 - 3.6e-09 36.7 9.2 2e-08 34.2 9.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KFM65368.1 - 0.00028 20.6 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 KFM65368.1 - 0.0025 17.3 2.2 0.0035 16.9 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase HTH_48 PF17906.1 KFM65369.1 - 2.9e-25 88.1 1.6 3.2e-25 88.0 1.6 1.0 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF4817 PF16087.5 KFM65369.1 - 0.0019 17.9 0.2 0.0023 17.7 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_Tnp_Tc3_2 PF01498.18 KFM65370.1 - 2.1e-16 59.9 2.2 4.4e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65370.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65373.1 - 8.8e-18 64.3 0.5 2.3e-17 63.0 0.5 1.8 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM65373.1 - 0.0018 18.8 1.7 0.01 16.4 0.9 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 KFM65373.1 - 0.0029 17.3 0.0 0.0086 15.8 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65373.1 - 0.0033 17.2 0.2 0.023 14.5 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM65373.1 - 0.063 13.4 0.1 0.18 11.9 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KFM65373.1 - 0.075 13.4 0.2 0.18 12.2 0.2 1.7 1 0 0 1 1 1 0 Transposase Cys_Met_Meta_PP PF01053.20 KFM65374.1 - 7.5e-154 511.9 0.0 8.5e-154 511.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFM65374.1 - 6.5e-12 45.3 0.0 8.6e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KFM65374.1 - 3.4e-06 25.8 0.0 4.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 KFM65374.1 - 0.0011 17.9 0.0 0.025 13.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFM65374.1 - 0.0027 17.0 0.0 0.009 15.3 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KFM65374.1 - 0.0088 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein DegT_DnrJ_EryC1 PF01041.17 KFM65374.1 - 0.0089 15.4 0.0 0.04 13.2 0.0 2.0 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family eIF-5_eIF-2B PF01873.17 KFM65376.1 - 2.8e-39 133.6 1.0 5.9e-39 132.6 0.4 1.8 2 0 0 2 2 2 1 Domain found in IF2B/IF5 Elf1 PF05129.13 KFM65376.1 - 1.3 9.1 7.0 0.1 12.6 1.7 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like HTH_48 PF17906.1 KFM65379.1 - 2.2e-08 34.1 0.7 6.1e-08 32.7 0.3 1.9 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_26 PF13443.6 KFM65379.1 - 0.0058 17.1 0.0 0.016 15.7 0.0 1.7 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_11 PF08279.12 KFM65379.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 HTH domain XRN1_D2_D3 PF18334.1 KFM65379.1 - 0.015 15.5 0.1 0.034 14.3 0.1 1.6 1 1 0 1 1 1 0 Exoribonuclease Xrn1 D2/D3 domain DUF5578 PF17741.1 KFM65379.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5578) HTH_DeoR PF08220.12 KFM65379.1 - 0.046 13.5 0.1 0.094 12.5 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DUF2399 PF09664.10 KFM65379.1 - 0.055 13.4 0.4 0.37 10.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) Spc7_N PF15402.6 KFM65380.1 - 0.56 8.4 6.4 0.63 8.2 6.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 fn3 PF00041.21 KFM65383.1 - 3.3e-07 30.6 0.6 5.9e-07 29.8 0.6 1.4 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM65383.1 - 0.034 14.7 0.1 0.059 14.0 0.1 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain 5_nucleotid PF05761.14 KFM65385.1 - 1.3e-140 469.3 0.0 1.7e-140 469.0 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase family DUF3958 PF13125.6 KFM65385.1 - 0.12 12.6 0.3 4.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) TPR_2 PF07719.17 KFM65386.1 - 1.5e-18 65.3 3.4 3.1e-05 23.7 0.4 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM65386.1 - 4.2e-18 64.3 4.7 1.5e-05 24.6 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 KFM65386.1 - 5.7e-15 55.8 4.6 1.1e-14 54.9 4.6 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_11 PF13414.6 KFM65386.1 - 4.6e-11 42.2 0.8 1.9e-05 24.3 0.0 3.2 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 KFM65386.1 - 1.4e-10 40.6 2.0 0.0002 21.3 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM65386.1 - 2.2e-09 37.4 2.5 3.7e-09 36.7 2.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFM65386.1 - 1.9e-08 34.5 4.2 1.9e-06 28.1 3.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM65386.1 - 4.6e-08 33.6 0.0 0.0053 17.4 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM65386.1 - 2.8e-07 30.8 0.4 0.00072 20.2 0.2 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM65386.1 - 5.5e-07 29.6 2.1 0.0023 18.0 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM65386.1 - 1.2e-06 29.0 0.2 0.0091 16.5 0.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM65386.1 - 7.5e-06 26.0 0.5 0.0075 16.6 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM65386.1 - 1.8e-05 24.4 4.7 0.064 13.3 0.2 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM65386.1 - 0.0031 18.0 1.8 3.4 8.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat SPO22 PF08631.10 KFM65386.1 - 0.0036 16.9 0.3 0.012 15.1 0.1 1.9 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like NRBF2_MIT PF17169.4 KFM65386.1 - 0.0082 16.3 0.9 0.082 13.1 0.0 2.7 3 1 0 3 3 3 1 MIT domain of nuclear receptor-binding factor 2 SHNi-TPR PF10516.9 KFM65386.1 - 0.019 14.4 1.2 2.3 7.8 0.1 3.6 4 0 0 4 4 4 0 SHNi-TPR SRP_TPR_like PF17004.5 KFM65386.1 - 0.052 13.6 0.6 0.32 11.0 0.4 2.2 1 1 0 1 1 1 0 Putative TPR-like repeat Sel1 PF08238.12 KFM65386.1 - 0.066 13.9 0.3 0.25 12.1 0.1 2.1 2 0 0 2 2 2 0 Sel1 repeat TPR_10 PF13374.6 KFM65386.1 - 0.18 11.7 1.6 7.3 6.6 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat FYVE PF01363.21 KFM65387.1 - 1e-16 60.8 15.2 1.9e-16 59.9 15.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger Arm_2 PF04826.13 KFM65387.1 - 1e-05 25.1 12.2 0.0034 16.9 9.4 2.5 1 1 1 2 2 2 2 Armadillo-like DUF3361 PF11841.8 KFM65387.1 - 0.0049 16.8 2.2 0.0049 16.8 2.2 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF3361) Arm PF00514.23 KFM65387.1 - 0.061 13.4 10.9 1.8 8.7 0.0 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat SIL1 PF16782.5 KFM65387.1 - 0.064 12.5 1.0 0.11 11.7 0.8 1.5 1 1 0 1 1 1 0 Nucleotide exchange factor SIL1 FYVE_2 PF02318.16 KFM65387.1 - 2 8.6 16.0 0.3 11.3 11.0 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger DZR PF12773.7 KFM65387.1 - 8.4 6.5 16.8 1e+03 -0.2 16.8 2.5 1 1 0 1 1 1 0 Double zinc ribbon CaMKII_AD PF08332.10 KFM65388.1 - 1.5e-61 206.2 0.1 2.6e-61 205.4 0.1 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 KFM65388.1 - 1.2e-10 41.7 0.0 2.7e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KFM65388.1 - 8.2e-09 35.8 0.1 1.6e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 SnoaL-like domain Pkinase PF00069.25 KFM65388.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain Homeodomain PF00046.29 KFM65389.1 - 2.8e-22 78.3 5.8 5.7e-22 77.3 5.8 1.5 1 0 0 1 1 1 1 Homeodomain DDE_3 PF13358.6 KFM65390.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease GTP_cyclohydro2 PF00925.20 KFM65390.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II DDE_Tnp_1_7 PF13843.6 KFM65393.1 - 3.6e-71 240.3 0.3 4.6e-71 240.0 0.3 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM65393.1 - 0.0011 18.6 0.0 0.0026 17.5 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain MFMR_assoc PF16596.5 KFM65393.1 - 2.2 8.7 4.1 0.79 10.2 1.3 1.6 2 0 0 2 2 2 0 Disordered region downstream of MFMR DDE_3 PF13358.6 KFM65394.1 - 3e-16 59.5 0.1 2.6e-15 56.5 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65394.1 - 1.3e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM65395.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65395.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5405 PF17399.2 KFM65400.1 - 0.036 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5405) YmgB PF10798.8 KFM65401.1 - 0.16 11.8 1.7 0.26 11.1 0.8 1.9 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR DUF43 PF01861.16 KFM65402.1 - 0.14 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Sugar_tr PF00083.24 KFM65404.1 - 2.7e-126 422.1 32.2 3.2e-126 421.8 32.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM65404.1 - 3.6e-19 68.9 31.4 3.6e-19 68.9 31.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KFM65404.1 - 0.02 15.4 2.4 0.02 15.4 2.4 2.7 3 0 0 3 3 3 0 Phage holin family 2 SNN_transmemb PF09049.10 KFM65404.1 - 0.085 12.8 0.2 0.085 12.8 0.2 3.6 3 1 1 4 4 4 0 Stannin transmembrane Fzo_mitofusin PF04799.13 KFM65406.1 - 3.1e-62 208.9 0.5 3.1e-62 208.9 0.5 3.7 3 1 0 3 3 3 1 fzo-like conserved region Dynamin_N PF00350.23 KFM65406.1 - 2.6e-23 82.9 0.1 1.2e-22 80.8 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFM65406.1 - 3.3e-07 30.4 0.0 1.7e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3189 PF11385.8 KFM65406.1 - 0.0054 16.6 0.0 0.021 14.7 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3189) AIG1 PF04548.16 KFM65406.1 - 0.009 15.4 0.0 0.029 13.7 0.0 1.9 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KFM65406.1 - 0.076 12.9 2.5 0.13 12.2 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 KFM65406.1 - 0.92 10.0 3.3 22 5.5 0.0 3.3 2 1 1 4 4 4 0 ABC transporter Focal_AT PF03623.13 KFM65406.1 - 3.9 7.5 8.9 0.76 9.8 1.3 3.3 3 1 0 3 3 3 0 Focal adhesion targeting region Baculo_p24 PF05073.12 KFM65406.1 - 6.7 6.5 11.6 30 4.3 0.8 3.4 3 0 0 3 3 3 0 Baculovirus P24 capsid protein DDOST_48kD PF03345.14 KFM65407.1 - 3.4e-154 513.7 0.1 3.8e-154 513.5 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Ceramidase_alk PF04734.13 KFM65407.1 - 0.18 10.4 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ost4 PF10215.9 KFM65407.1 - 0.26 11.1 1.8 0.67 9.8 1.8 1.7 1 0 0 1 1 1 0 Oligosaccaryltransferase HTH_Tnp_Tc3_2 PF01498.18 KFM65408.1 - 1.2e-16 60.6 2.6 5.9e-16 58.5 0.6 2.1 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM65408.1 - 6.3e-07 29.9 4.0 1e-06 29.2 1.2 2.0 1 1 1 2 2 2 2 Homeodomain-like domain MarR_2 PF12802.7 KFM65408.1 - 4.5e-05 23.2 0.5 0.00098 19.0 0.0 2.3 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM65408.1 - 9.5e-05 22.3 0.1 0.0034 17.3 0.0 2.2 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KFM65408.1 - 0.0002 21.0 1.5 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.6 KFM65408.1 - 0.00048 20.1 1.2 0.0036 17.3 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM65408.1 - 0.0027 17.8 2.7 0.056 13.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 KFM65408.1 - 0.029 14.3 0.0 2.3 8.2 0.0 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_26 PF13443.6 KFM65408.1 - 0.029 14.8 0.4 2.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Fe_dep_repress PF01325.19 KFM65408.1 - 0.045 14.0 0.0 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain GntR PF00392.21 KFM65408.1 - 0.11 12.1 0.1 1.1 9.0 0.0 2.2 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family zf-H2C2_2 PF13465.6 KFM65412.1 - 2e-29 100.7 50.6 4.1e-08 33.3 0.6 8.1 7 1 1 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65412.1 - 4.2e-21 74.1 54.9 6.5e-06 26.3 1.9 7.5 7 1 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65412.1 - 2.4e-20 71.5 51.0 0.00029 21.4 1.4 7.2 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65412.1 - 4.7e-15 55.2 45.4 0.00014 21.7 0.3 7.3 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM65412.1 - 1.5e-10 41.1 53.9 0.00063 20.0 0.7 8.2 8 1 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65412.1 - 2.2e-08 34.2 40.8 0.00028 21.1 1.2 7.6 7 1 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM65412.1 - 7.4e-06 25.6 5.7 0.00028 20.6 1.0 5.9 6 1 0 6 6 6 2 zinc-finger C2H2-type Spike_NTD PF16451.5 KFM65412.1 - 0.0047 16.3 2.7 0.0059 16.0 2.7 1.2 1 0 0 1 1 1 1 Spike glycoprotein N-terminal domain GAGA PF09237.11 KFM65412.1 - 0.04 13.7 4.3 0.098 12.5 0.1 3.5 2 1 1 3 3 3 0 GAGA factor zf_UBZ PF18439.1 KFM65412.1 - 0.066 12.8 30.3 0.99 9.1 0.1 6.6 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger FYDLN_acid PF09538.10 KFM65412.1 - 3 8.6 6.8 40 5.0 0.0 4.0 2 1 2 4 4 4 0 Protein of unknown function (FYDLN_acid) DUF2721 PF11026.8 KFM65413.1 - 0.088 12.7 0.0 0.091 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) B12D PF06522.11 KFM65414.1 - 4.3e-05 23.2 0.0 5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF5641 PF18701.1 KFM65415.1 - 5.3e-17 61.8 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 KFM65415.1 - 1.8e-10 40.8 0.4 3.8e-10 39.7 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM65415.1 - 0.0034 17.6 0.4 0.009 16.2 0.4 1.7 1 0 0 1 1 1 1 H2C2 zinc finger VPR PF00522.18 KFM65415.1 - 0.31 11.1 2.2 0.35 10.9 0.3 2.1 2 0 0 2 2 2 0 VPR/VPX protein Avidin PF01382.17 KFM65416.1 - 1.9e-39 134.7 2.3 1.3e-29 103.0 0.2 2.9 2 1 0 2 2 2 2 Avidin family Avidin PF01382.17 KFM65417.1 - 2.4e-32 111.8 0.9 1.2e-29 103.1 0.3 2.3 2 1 0 2 2 2 2 Avidin family MFS_1 PF07690.16 KFM65418.1 - 1.3e-05 24.3 12.1 0.0079 15.1 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GtrA PF04138.14 KFM65418.1 - 0.42 10.9 7.1 1.9 8.8 0.4 2.7 1 1 0 2 2 2 0 GtrA-like protein DUF4282 PF14110.6 KFM65418.1 - 2.4 8.9 6.6 0.51 11.1 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) DDE_3 PF13358.6 KFM65421.1 - 1.6e-14 53.9 0.0 2.3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65421.1 - 1.4e-08 34.8 0.2 3.3e-08 33.7 0.2 1.5 1 0 0 1 1 1 1 Transposase DAG_kinase_N PF14513.6 KFM65423.1 - 1.7e-18 67.4 0.8 1.9e-18 67.2 0.8 1.0 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus XPC-binding PF09280.11 KFM65423.1 - 0.094 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 XPC-binding domain C1_1 PF00130.22 KFM65424.1 - 1.3e-18 66.6 24.1 1.1e-11 44.4 14.4 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFM65424.1 - 0.0034 17.7 18.6 0.053 13.8 8.9 2.5 2 0 0 2 2 2 2 C1 domain RE_BsaWI PF18643.1 KFM65424.1 - 0.19 11.7 0.1 0.29 11.1 0.1 1.2 1 0 0 1 1 1 0 BsaWI restriction endonuclease type 2 DAGK_acc PF00609.19 KFM65425.1 - 3.5e-53 180.2 0.1 4.8e-53 179.8 0.1 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFM65425.1 - 6.9e-18 64.5 0.0 1.2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4780 PF16012.5 KFM65425.1 - 0.062 12.8 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) BTB PF00651.31 KFM65426.1 - 1.3e-34 118.8 9.3 2.2e-17 63.3 0.2 3.5 2 1 1 3 3 3 2 BTB/POZ domain RCC1 PF00415.18 KFM65426.1 - 2.5e-32 111.2 5.8 2.1e-09 37.9 0.7 4.8 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 KFM65426.1 - 1.7e-10 40.9 0.1 0.00045 20.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM65426.1 - 8.1e-09 36.0 0.0 2.1e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM65426.1 - 1.2e-06 28.3 0.4 0.0011 19.2 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KFM65426.1 - 1.9e-06 28.3 0.1 4.6e-05 23.9 0.1 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM65426.1 - 2.8e-06 27.5 0.1 0.04 14.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat RCC1_2 PF13540.6 KFM65426.1 - 2.9e-06 26.9 14.5 0.0002 21.1 0.7 4.7 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat DUF3342 PF11822.8 KFM65426.1 - 0.064 13.4 5.6 0.76 10.0 0.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) BIR PF00653.21 KFM65428.1 - 1.2e-36 125.1 9.8 1.5e-18 67.2 0.0 3.5 3 1 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 KFM65428.1 - 1.4e-13 50.4 8.2 1.4e-13 50.4 8.2 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM65428.1 - 2.4e-05 24.1 8.9 2.4e-05 24.1 8.9 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFM65428.1 - 0.0025 17.6 9.7 0.023 14.6 6.6 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM65428.1 - 0.0031 17.4 11.5 0.016 15.1 8.8 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFM65428.1 - 0.028 14.8 8.6 0.028 14.8 8.6 3.6 2 2 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 KFM65428.1 - 0.12 12.2 2.4 1.3 8.8 1.2 2.7 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KFM65428.1 - 0.16 12.0 8.4 0.1 12.6 4.2 3.0 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFM65428.1 - 0.45 10.4 16.6 0.089 12.7 8.9 3.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C2HC_2 PF13913.6 KFM65428.1 - 5.3 7.1 6.8 31 4.6 0.1 3.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type LIM PF00412.22 KFM65429.1 - 1.1e-24 86.4 24.9 1.1e-12 48.0 7.3 2.1 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 KFM65429.1 - 0.022 14.3 15.3 0.58 9.8 0.0 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-CCHC_5 PF14787.6 KFM65429.1 - 1.1 9.1 0.1 1.1 9.1 0.1 3.7 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger SelR PF01641.18 KFM65429.1 - 1.7 8.7 9.2 5 7.2 0.8 2.2 2 0 0 2 2 2 0 SelR domain zf-SNAP50_C PF12251.8 KFM65429.1 - 4.2 7.0 13.1 0.89 9.2 0.6 2.6 2 1 1 3 3 3 0 snRNA-activating protein of 50kDa MW C terminal DUF4428 PF14471.6 KFM65429.1 - 8.5 6.4 15.3 1.3 9.0 2.3 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4428) RVT_1 PF00078.27 KFM65430.1 - 5e-51 173.3 0.2 8.9e-51 172.5 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KFM65430.1 - 6.4e-11 42.6 0.0 2.2e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 RNase H HTH_Tnp_Tc3_2 PF01498.18 KFM65431.1 - 1.3e-06 28.5 0.4 3e-06 27.4 0.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65431.1 - 4.6e-06 26.4 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Cnd2 PF05786.14 KFM65432.1 - 1.5e-26 93.4 6.2 1.8e-26 93.1 6.2 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KFM65432.1 - 4.8e-05 23.5 0.4 4.8e-05 23.5 0.4 2.1 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal zf-NOSIP PF15906.5 KFM65432.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein zf-H2C2_2 PF13465.6 KFM65434.1 - 3.4e-57 188.5 65.8 8.4e-08 32.3 0.3 9.1 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65434.1 - 1.9e-37 125.6 76.6 3.6e-05 24.0 2.1 9.1 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65434.1 - 1.4e-27 94.0 72.4 0.0008 20.0 1.2 9.1 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM65434.1 - 3.6e-18 65.3 65.7 0.0077 16.6 0.8 9.2 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65434.1 - 4.8e-12 45.5 64.3 0.063 13.3 1.6 9.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65434.1 - 5.1e-10 39.4 47.9 0.018 15.4 0.2 9.3 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM65434.1 - 5.1e-09 36.0 27.4 0.17 11.9 0.1 8.7 5 3 4 9 9 9 3 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM65434.1 - 3.8e-07 30.2 37.1 0.00048 20.2 5.8 4.1 1 1 4 5 5 5 4 Putative ribonucleoprotein zinc-finger pf C4 type GAGA PF09237.11 KFM65434.1 - 7.1e-06 25.7 17.7 0.064 13.1 0.0 6.0 1 1 6 7 7 7 3 GAGA factor BolA PF01722.18 KFM65434.1 - 2.2e-05 24.6 17.2 1.4 9.2 0.1 5.6 1 1 4 5 5 5 2 BolA-like protein zf-C2HC_2 PF13913.6 KFM65434.1 - 6.1e-05 22.8 39.7 1.6 8.7 0.9 9.0 9 0 0 9 9 9 3 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM65434.1 - 0.00011 22.2 39.2 6.5 7.0 0.1 9.1 8 1 1 9 9 9 0 DBF zinc finger ADK_lid PF05191.14 KFM65434.1 - 0.0014 18.6 31.2 5 7.2 0.1 6.4 3 3 3 6 6 6 1 Adenylate kinase, active site lid DZR PF12773.7 KFM65434.1 - 0.0015 18.5 31.9 1.8e+04 -16.0 31.9 5.4 1 1 0 1 1 0 0 Double zinc ribbon zf-C2H2_9 PF16293.5 KFM65434.1 - 0.0044 16.8 35.2 1 9.2 0.2 7.4 2 2 6 8 8 8 3 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KFM65434.1 - 0.0048 16.5 43.2 0.13 11.9 0.4 8.6 4 3 5 9 9 9 2 MYST family zinc finger domain C1_1 PF00130.22 KFM65434.1 - 0.018 14.9 53.2 5.4 7.0 0.4 8.7 3 2 3 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 KFM65434.1 - 0.019 15.1 35.2 15 5.8 0.2 8.9 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFM65434.1 - 0.036 14.8 38.4 0.77 10.6 4.6 4.8 1 1 2 5 5 5 0 zinc-ribbon family OSTMP1 PF09777.9 KFM65434.1 - 0.062 12.7 26.8 0.41 10.0 12.4 4.4 1 1 2 3 3 3 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-FPG_IleRS PF06827.14 KFM65434.1 - 0.063 13.2 27.1 9.5 6.2 0.2 8.0 9 0 0 9 9 9 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 KFM65434.1 - 0.09 12.9 32.6 0.37 11.0 0.9 6.2 3 1 4 7 7 7 0 Zinc ribbon domain HTH_34 PF13601.6 KFM65434.1 - 0.18 12.0 2.4 4.6 7.5 0.0 3.8 4 1 1 5 5 4 0 Winged helix DNA-binding domain Zf_RING PF16744.5 KFM65434.1 - 0.19 11.9 44.8 1.8 8.7 1.5 8.6 1 1 5 7 7 7 0 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KFM65434.1 - 0.19 12.1 56.6 3.6 8.0 1.5 7.5 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) YyzF PF14116.6 KFM65434.1 - 0.2 11.7 31.1 20 5.3 0.1 8.7 9 0 0 9 9 9 0 YyzF-like protein DNA_pol3_chi PF04364.13 KFM65434.1 - 0.27 11.4 2.5 27 4.9 0.0 4.6 1 1 5 7 7 7 0 DNA polymerase III chi subunit, HolC PqqA PF08042.11 KFM65434.1 - 0.52 10.4 1.7 4e+02 1.3 0.0 4.4 5 0 0 5 5 4 0 PqqA family zf-Paramyx-P PF13008.7 KFM65434.1 - 0.69 9.4 26.4 1.8 8.1 0.1 7.0 8 0 0 8 8 7 0 Zinc-binding domain of Paramyxoviridae V protein DUF1930 PF09122.10 KFM65434.1 - 2.5 8.1 9.9 8.9 6.4 0.2 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF1930) Amidohydro_1 PF01979.20 KFM65434.1 - 5.8 6.1 12.6 22 4.2 0.6 4.7 1 1 3 4 4 4 0 Amidohydrolase family FYVE PF01363.21 KFM65434.1 - 6.9 6.9 46.0 14 5.9 9.8 5.4 1 1 4 5 5 5 0 FYVE zinc finger zf-H2C2_2 PF13465.6 KFM65435.1 - 2e-17 62.8 13.2 7.9e-08 32.4 2.9 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65435.1 - 2.7e-12 46.4 14.2 1.1e-06 28.7 1.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65435.1 - 8.8e-08 32.4 12.5 0.00076 20.1 1.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM65435.1 - 4.8e-07 30.0 8.2 0.0043 17.4 0.6 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65435.1 - 6.8e-07 29.1 10.3 0.00061 19.7 0.3 2.6 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65435.1 - 1.5e-05 25.1 1.8 0.024 14.9 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM65435.1 - 0.0015 18.3 2.2 0.16 11.8 0.5 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFM65435.1 - 0.0076 16.6 6.3 0.63 10.4 1.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFM65435.1 - 0.03 14.2 4.8 1.9 8.4 0.6 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 KFM65435.1 - 0.035 14.2 0.2 0.04 14.0 0.2 1.1 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM65435.1 - 0.044 13.9 2.1 5.5 7.2 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.16 KFM65435.1 - 0.13 12.1 4.1 4 7.4 0.2 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-MYST PF17772.1 KFM65435.1 - 0.16 11.6 2.3 1.9 8.1 0.2 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain Rtf2 PF04641.12 KFM65435.1 - 0.24 10.7 2.2 5.7 6.2 0.1 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger zf_C2H2_ZHX PF18387.1 KFM65435.1 - 1 9.1 7.0 2.3 7.9 0.4 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Vps39_2 PF10367.9 KFM65435.1 - 1.2 9.6 6.3 8.9 6.8 0.4 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-CCHC PF00098.23 KFM65436.1 - 9.1e-06 25.5 1.4 1.4e-05 25.0 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM65436.1 - 0.0036 17.0 0.4 0.0062 16.2 0.4 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM65436.1 - 0.085 12.6 0.7 0.14 11.9 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle Chitin_bind_4 PF00379.23 KFM65437.1 - 4.8e-08 33.4 0.1 6.7e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM65439.1 - 1.1e-08 35.4 0.5 1.7e-08 34.8 0.5 1.3 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM65441.1 - 4e-08 33.7 0.4 5.6e-08 33.2 0.4 1.2 1 0 0 1 1 1 1 Insect cuticle protein Vitellogenin_N PF01347.22 KFM65445.1 - 5.9e-75 252.9 0.0 1e-74 252.1 0.0 1.4 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 KFM65445.1 - 2e-65 221.1 5.1 1.5e-63 214.9 1.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF1943) VWD PF00094.25 KFM65445.1 - 1.8e-18 67.3 0.1 1.8e-18 67.3 0.1 4.6 5 0 0 5 5 5 1 von Willebrand factor type D domain C8 PF08742.11 KFM65445.1 - 9.5e-09 35.6 5.6 2.2e-08 34.4 5.6 1.7 1 0 0 1 1 1 1 C8 domain DUF1081 PF06448.11 KFM65445.1 - 2.9e-07 30.8 14.5 0.00028 21.3 0.0 7.7 7 1 1 8 8 8 2 Domain of Unknown Function (DUF1081) DUF1104 PF06518.11 KFM65445.1 - 0.026 14.9 0.0 0.13 12.6 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) SPATA1_C PF15743.5 KFM65446.1 - 3.1e-25 89.0 21.2 3.1e-25 89.0 21.2 3.0 4 1 0 4 4 4 1 Spermatogenesis-associated C-terminus Lipoprotein_17 PF04200.12 KFM65446.1 - 0.72 10.2 11.3 0.2 12.0 7.3 2.2 2 0 0 2 2 2 0 Lipoprotein associated domain FUSC PF04632.12 KFM65446.1 - 9.9 4.6 7.9 16 3.9 7.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Formyl_trans_N PF00551.19 KFM65447.1 - 0.13 11.9 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Formyl transferase zf-C2HC_2 PF13913.6 KFM65448.1 - 0.27 11.2 2.5 0.56 10.2 2.5 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type UCH PF00443.29 KFM65449.1 - 7.5e-45 153.4 0.2 1.5e-44 152.5 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM65449.1 - 3.8e-29 102.3 0.0 1.4e-28 100.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNA_pol_Rpb4 PF03874.16 KFM65450.1 - 0.067 13.5 0.4 0.24 11.7 0.4 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb4 UBA PF00627.31 KFM65451.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain DUF1759 PF03564.15 KFM65453.1 - 0.0036 17.2 0.0 0.0036 17.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) RVT_1 PF00078.27 KFM65454.1 - 0.085 12.4 0.0 0.088 12.3 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 KFM65455.1 - 7.8e-30 101.7 58.1 2.8e-06 27.5 3.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM65455.1 - 2.4e-29 100.4 47.7 3.6e-08 33.5 0.5 7.2 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM65455.1 - 1.3e-22 78.5 53.3 0.00027 21.5 1.1 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFM65455.1 - 5.2e-08 33.0 52.2 0.025 15.0 1.1 7.5 6 1 1 7 7 7 5 Zinc-finger of C2H2 type BolA PF01722.18 KFM65455.1 - 2.6e-07 30.8 4.2 0.38 11.1 0.1 4.7 2 2 4 6 6 6 3 BolA-like protein GAGA PF09237.11 KFM65455.1 - 7.8e-07 28.8 11.0 0.025 14.4 0.0 5.0 1 1 4 5 5 5 3 GAGA factor zf-C2H2_6 PF13912.6 KFM65455.1 - 7.8e-06 25.8 53.2 0.0014 18.5 0.4 7.7 7 1 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65455.1 - 0.00021 21.5 43.2 0.24 11.7 0.4 6.6 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM65455.1 - 0.00083 19.6 33.5 0.0091 16.3 1.4 4.4 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFM65455.1 - 0.006 16.3 1.4 0.006 16.3 1.4 6.5 5 1 1 6 6 6 3 C2H2-type zinc-finger domain Baculo_IE-1 PF05290.11 KFM65455.1 - 0.02 14.8 22.0 0.32 10.9 0.7 4.7 1 1 3 4 4 4 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_11 PF16622.5 KFM65455.1 - 0.027 14.3 0.5 0.027 14.3 0.5 4.9 5 0 0 5 5 5 0 zinc-finger C2H2-type TRAF6_Z2 PF18048.1 KFM65455.1 - 0.27 11.4 0.3 0.27 11.4 0.3 5.8 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 zf-UBR PF02207.20 KFM65455.1 - 0.54 10.5 34.3 9.5 6.5 3.3 3.9 1 1 2 3 3 3 0 Putative zinc finger in N-recognin (UBR box) FYVE PF01363.21 KFM65455.1 - 0.56 10.4 39.4 3.9 7.7 18.0 4.1 1 1 1 3 3 3 0 FYVE zinc finger Scramblase PF03803.15 KFM65455.1 - 1.1 8.5 5.7 1.4 8.2 2.5 2.1 1 1 1 2 2 2 0 Scramblase zf-MYST PF17772.1 KFM65455.1 - 8.3 6.1 27.5 0.21 11.2 0.3 5.6 3 2 3 6 6 6 0 MYST family zinc finger domain TIL PF01826.17 KFM65456.1 - 1.5e-27 95.6 39.8 7.2e-16 58.2 13.8 3.9 2 1 1 3 3 3 2 Trypsin Inhibitor like cysteine rich domain Kunitz_BPTI PF00014.23 KFM65456.1 - 3.2e-19 68.9 10.2 3.2e-19 68.9 10.2 4.1 2 2 1 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain TIL PF01826.17 KFM65457.1 - 1e-16 60.9 29.3 1.2e-09 38.2 11.5 2.0 2 0 0 2 2 2 2 Trypsin Inhibitor like cysteine rich domain GBP_PSP PF02425.15 KFM65457.1 - 0.0027 17.3 14.6 0.0069 16.0 2.2 3.1 3 0 0 3 3 3 2 Paralytic/GBP/PSP peptide cEGF PF12662.7 KFM65457.1 - 1.2 9.1 16.5 0.91 9.5 5.1 3.3 3 0 0 3 3 3 0 Complement Clr-like EGF-like Kunitz_BPTI PF00014.23 KFM65460.1 - 2.4e-73 242.2 68.8 7.7e-21 74.1 5.8 5.1 5 0 0 5 5 5 4 Kunitz/Bovine pancreatic trypsin inhibitor domain TIL PF01826.17 KFM65460.1 - 1.4e-24 86.0 39.8 2.6e-13 50.0 15.8 6.6 5 3 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain DUF2724 PF10893.8 KFM65460.1 - 0.0099 15.7 0.3 0.99 9.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2724) WW PF00397.26 KFM65460.1 - 0.093 12.8 7.5 3.4 7.8 0.1 3.8 4 0 0 4 4 4 0 WW domain Ribosomal_S27 PF01599.19 KFM65460.1 - 0.094 12.9 0.1 0.094 12.9 0.1 4.8 4 0 0 4 4 4 0 Ribosomal protein S27a Kelch_3 PF13415.6 KFM65460.1 - 0.73 10.2 4.5 34 4.9 0.1 4.0 4 0 0 4 4 4 0 Galactose oxidase, central domain Transposase_1 PF01359.18 KFM65461.1 - 7e-26 89.9 2.4 8.3e-26 89.6 0.7 1.9 2 0 0 2 2 2 1 Transposase (partial DDE domain) TIL PF01826.17 KFM65461.1 - 3.6e-12 46.4 16.4 8.3e-12 45.2 16.4 1.7 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain DDE_3 PF13358.6 KFM65461.1 - 1.7e-05 24.6 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_48 PF17906.1 KFM65461.1 - 0.00038 20.5 0.1 0.00098 19.2 0.1 1.7 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_50 PF18024.1 KFM65461.1 - 0.00048 19.7 0.0 0.00095 18.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM65461.1 - 0.0054 17.3 0.0 0.017 15.7 0.0 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM65461.1 - 0.0072 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_10 PF04967.12 KFM65461.1 - 0.04 13.7 0.1 0.082 12.7 0.1 1.4 1 0 0 1 1 1 0 HTH DNA binding domain TIL PF01826.17 KFM65462.1 - 4.8e-14 52.3 19.6 5.6e-14 52.1 19.6 1.0 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain Kunitz_BPTI PF00014.23 KFM65463.1 - 4.5e-19 68.4 10.2 5.3e-19 68.2 10.2 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain HTH_Tnp_Tc3_2 PF01498.18 KFM65464.1 - 5.5e-17 61.8 2.7 5.5e-17 61.8 2.7 1.7 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 KFM65464.1 - 2.7e-05 24.2 5.0 2.7e-05 24.2 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65464.1 - 0.00075 19.2 0.6 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65464.1 - 0.013 16.1 2.4 0.013 16.1 2.4 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KFM65464.1 - 0.013 14.9 2.5 0.035 13.5 0.0 2.9 3 1 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 KFM65464.1 - 0.021 14.5 0.0 0.089 12.4 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain KH_1 PF00013.29 KFM65465.1 - 7.2e-27 93.0 1.5 2.7e-14 52.8 0.2 2.3 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 KFM65465.1 - 2.9e-11 43.0 11.5 4.8e-11 42.4 11.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM65465.1 - 3e-06 27.0 11.3 5.5e-06 26.2 11.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFM65465.1 - 6.2e-06 26.4 10.8 1.1e-05 25.6 10.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFM65465.1 - 0.00022 21.0 12.2 0.00043 20.1 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_2 PF07650.17 KFM65465.1 - 0.00072 19.3 0.1 0.22 11.4 0.0 2.4 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 KFM65465.1 - 0.0011 18.7 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 KH domain zf-C3HC4_2 PF13923.6 KFM65465.1 - 0.0015 18.3 10.9 0.003 17.3 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM65465.1 - 0.0016 18.3 10.2 0.0033 17.3 10.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM65465.1 - 0.012 15.6 6.0 0.015 15.3 3.0 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 KFM65465.1 - 0.16 11.8 9.9 0.32 10.8 9.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFM65465.1 - 0.75 10.0 11.9 1.8 8.8 11.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 KFM65465.1 - 0.77 9.5 4.8 1.4 8.7 4.8 1.4 1 0 0 1 1 1 0 P-11 zinc finger DSPc PF00782.20 KFM65466.1 - 7.4e-31 106.7 0.0 1.1e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM65466.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Phage_min_tail PF05939.13 KFM65467.1 - 0.066 13.6 0.0 0.099 13.0 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein HTH_Tnp_Tc3_2 PF01498.18 KFM65468.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65468.1 - 1e-13 51.2 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65468.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65468.1 - 0.0023 17.7 0.6 0.0068 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65468.1 - 1.8 9.2 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Lipase PF00151.19 KFM65469.1 - 7.8e-16 58.3 2.7 1.1e-15 57.9 2.7 1.2 1 0 0 1 1 1 1 Lipase adh_short PF00106.25 KFM65470.1 - 1.1e-40 139.2 0.0 1.4e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM65470.1 - 2e-29 102.8 0.0 2.4e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM65470.1 - 1.3e-16 61.1 0.0 1.7e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFM65470.1 - 5.2e-05 23.2 0.2 7.1e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFM65470.1 - 8.7e-05 21.8 0.1 0.00011 21.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFM65470.1 - 0.0001 21.8 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM65470.1 - 0.0017 17.5 0.1 0.0022 17.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DFP PF04127.15 KFM65470.1 - 0.0033 17.3 0.0 0.0086 15.9 0.0 1.6 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein ThiF PF00899.21 KFM65470.1 - 0.011 15.1 1.7 0.014 14.8 1.7 1.6 1 1 0 1 1 1 0 ThiF family AAA_31 PF13614.6 KFM65470.1 - 0.011 15.7 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain Sacchrp_dh_NADP PF03435.18 KFM65470.1 - 0.014 15.7 0.1 0.02 15.2 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 KFM65470.1 - 0.019 15.6 0.2 0.12 13.1 0.2 1.9 1 1 1 2 2 2 0 Methyltransferase domain CbiA PF01656.23 KFM65470.1 - 0.027 14.5 0.1 0.04 14.0 0.1 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GDP_Man_Dehyd PF16363.5 KFM65470.1 - 0.036 13.5 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 KFM65470.1 - 0.047 13.3 0.1 0.061 13.0 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KFM65470.1 - 0.078 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KFM65470.1 - 0.17 11.8 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding NIF PF03031.18 KFM65471.1 - 6.2e-42 143.0 0.0 8.2e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sad1_UNC PF07738.13 KFM65473.1 - 2.9e-28 98.5 0.2 1e-27 96.7 0.2 2.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF2120 PF09893.9 KFM65473.1 - 9.6 6.3 9.9 1.5 8.9 3.8 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DDE_3 PF13358.6 KFM65474.1 - 8.2e-07 28.9 0.0 8.2e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.22 KFM65475.1 - 0.012 15.5 0.5 0.072 12.9 0.0 2.3 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFM65476.1 - 2.3e-18 65.8 0.0 1.9e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KFM65476.1 - 0.017 14.8 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_5 PF13893.6 KFM65476.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KFM65476.1 - 0.09 12.5 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain DDE_3 PF13358.6 KFM65477.1 - 1.2e-13 51.0 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PPO1_DWL PF12142.8 KFM65477.1 - 0.12 12.2 0.3 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Polyphenol oxidase middle domain HRM PF02793.22 KFM65478.1 - 0.00017 21.8 0.3 0.00017 21.8 0.3 1.0 1 0 0 1 1 1 1 Hormone receptor domain 7tm_2 PF00002.24 KFM65479.1 - 3.3e-18 65.9 3.1 3.3e-18 65.9 3.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) SLC35F PF06027.12 KFM65479.1 - 0.02 14.4 1.1 0.025 14.1 1.1 1.1 1 0 0 1 1 1 0 Solute carrier family 35 DUF2628 PF10947.8 KFM65479.1 - 0.85 10.0 5.4 1 9.7 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) 7tm_2 PF00002.24 KFM65480.1 - 2.7e-13 49.8 0.4 3.5e-13 49.4 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_7 PF08395.12 KFM65480.1 - 0.019 14.2 0.1 0.022 14.0 0.1 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor MULE PF10551.9 KFM65480.1 - 0.098 13.1 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 MULE transposase domain DUF4371 PF14291.6 KFM65483.1 - 1.9e-26 93.2 0.0 3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KFM65483.1 - 0.0037 17.2 0.1 0.0095 15.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RSS_P20 PF11757.8 KFM65483.1 - 0.048 14.1 0.1 0.13 12.7 0.1 1.8 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM65483.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Transposase gag-asp_proteas PF13975.6 KFM65484.1 - 4.5e-09 36.8 0.0 1.5e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM65484.1 - 5.3e-08 33.4 0.0 1.4e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Apolipoprotein PF01442.18 KFM65484.1 - 4.4e-07 30.0 13.0 7.5e-07 29.2 13.0 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin PF05597.11 KFM65484.1 - 0.0001 22.3 5.8 0.0001 22.3 5.8 2.4 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 KFM65484.1 - 0.00028 21.0 0.5 0.13 12.3 0.3 2.9 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 KFM65484.1 - 0.00034 20.7 14.2 0.00072 19.6 14.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1664 PF07889.12 KFM65484.1 - 0.022 14.8 17.0 0.6 10.2 6.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Asp_protease PF09668.10 KFM65484.1 - 0.05 13.4 1.6 0.31 10.8 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease DUF883 PF05957.13 KFM65484.1 - 0.073 13.7 10.5 1.5 9.4 2.9 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1351 PF07083.11 KFM65484.1 - 0.15 11.9 17.1 0.39 10.4 17.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) Prominin PF05478.11 KFM65484.1 - 0.19 9.6 12.2 0.18 9.7 5.1 1.9 1 1 0 1 1 1 0 Prominin GAS PF13851.6 KFM65484.1 - 0.27 10.6 14.9 0.49 9.7 14.9 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.11 KFM65484.1 - 0.3 10.9 6.1 0.6 9.9 2.6 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Peptidase_S64 PF08192.11 KFM65484.1 - 0.31 9.5 7.3 0.49 8.8 7.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 ApoLp-III PF07464.11 KFM65484.1 - 0.36 10.9 20.0 7 6.7 20.0 2.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ApoO PF09769.9 KFM65484.1 - 0.69 9.9 6.5 13 5.8 2.8 3.1 1 1 1 2 2 2 0 Apolipoprotein O CPSF73-100_C PF11718.8 KFM65484.1 - 1 8.8 8.6 2.3 7.7 8.3 1.7 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF3584 PF12128.8 KFM65484.1 - 1.1 6.7 14.5 2.8 5.4 14.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 KFM65484.1 - 1.4 9.4 9.7 6.9 7.2 1.8 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Nup88 PF10168.9 KFM65484.1 - 1.6 6.4 11.2 2.4 5.9 11.2 1.3 1 0 0 1 1 1 0 Nuclear pore component Syntaxin-6_N PF09177.11 KFM65484.1 - 1.8 9.2 11.6 2.7e+02 2.2 11.6 3.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF5082 PF16888.5 KFM65484.1 - 2.7 8.3 11.6 14 6.0 7.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4510 PF14971.6 KFM65484.1 - 3 8.2 6.3 3.9 7.8 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) Fib_alpha PF08702.10 KFM65484.1 - 3.3 7.9 18.4 1.3 9.3 4.3 3.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family PIN_8 PF18476.1 KFM65484.1 - 4.9 7.0 12.0 12 5.7 5.0 2.4 2 1 1 3 3 2 0 PIN like domain COG2 PF06148.11 KFM65484.1 - 5.1 7.2 20.4 30 4.7 8.0 3.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 EspB PF05802.11 KFM65484.1 - 5.5 6.9 14.7 8.2 6.4 12.8 2.0 1 1 1 2 2 2 0 Enterobacterial EspB protein Tweety PF04906.13 KFM65484.1 - 7.1 5.2 7.9 0.89 8.2 2.2 1.9 1 1 1 2 2 2 0 Tweety ABC_tran PF00005.27 KFM65485.1 - 1.2e-23 84.1 0.1 1.7e-23 83.7 0.1 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFM65485.1 - 2.7e-05 24.2 0.1 4.4e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KFM65485.1 - 0.00072 20.0 0.1 0.00095 19.6 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFM65485.1 - 0.00088 19.2 0.2 0.69 9.7 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KFM65485.1 - 0.0058 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM65485.1 - 0.006 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFM65485.1 - 0.01 15.9 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 KFM65485.1 - 0.014 14.8 0.1 0.1 12.0 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFM65485.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KFM65485.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFM65485.1 - 0.023 15.2 0.0 0.047 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFM65485.1 - 0.038 13.6 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KFM65485.1 - 0.049 13.4 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KFM65485.1 - 0.076 13.1 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 KFM65485.1 - 0.081 13.4 0.8 0.16 12.4 0.7 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFM65485.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PEPCK_ATP PF01293.20 KFM65485.1 - 0.14 10.8 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Septin PF00735.18 KFM65485.1 - 0.14 11.4 0.1 0.26 10.5 0.1 1.4 1 0 0 1 1 1 0 Septin MobB PF03205.14 KFM65485.1 - 0.15 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC2_membrane PF01061.24 KFM65486.1 - 1.7e-32 112.6 21.6 1.7e-32 112.6 21.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KFM65486.1 - 0.024 13.7 22.5 0.036 13.2 22.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein CitMHS PF03600.16 KFM65486.1 - 0.15 11.2 9.0 0.24 10.6 9.0 1.3 1 0 0 1 1 1 0 Citrate transporter PDR_CDR PF06422.12 KFM65486.1 - 9.5 6.2 8.0 0.27 11.2 0.5 2.4 2 2 1 3 3 3 0 CDR ABC transporter HTH_Tnp_Tc3_2 PF01498.18 KFM65487.1 - 2.5e-16 59.7 2.2 4.5e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65487.1 - 9.9e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Pro_isomerase PF00160.21 KFM65488.1 - 1.1e-38 133.0 0.0 3.5e-38 131.4 0.0 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KFM65488.1 - 2e-16 59.5 0.1 4.2e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fasciclin PF02469.22 KFM65490.1 - 1e-91 303.8 0.0 3.3e-28 98.5 0.0 4.1 4 0 0 4 4 4 4 Fasciclin domain LRV PF01816.17 KFM65490.1 - 0.082 13.3 0.6 0.4 11.2 0.6 2.3 1 0 0 1 1 1 0 Leucine rich repeat variant TrkA_N PF02254.18 KFM65490.1 - 0.13 12.5 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ECH_1 PF00378.20 KFM65491.1 - 1.8e-31 109.4 0.1 2.2e-31 109.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM65491.1 - 1e-11 45.0 0.0 5.3e-09 36.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CAP_GLY PF01302.25 KFM65492.1 - 1.1e-22 79.8 1.2 2.1e-22 78.9 1.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain COX5B PF01215.19 KFM65492.1 - 0.0057 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Innexin PF00876.18 KFM65493.1 - 8.8e-95 318.0 10.6 1e-94 317.8 10.6 1.0 1 0 0 1 1 1 1 Innexin Y_phosphatase2 PF03162.13 KFM65495.1 - 0.12 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family UME PF08064.13 KFM65500.1 - 7.6e-19 67.5 0.6 2e-17 63.0 0.1 3.1 3 1 0 3 3 3 1 UME (NUC010) domain HEAT PF02985.22 KFM65500.1 - 1.4e-05 24.9 0.0 0.55 10.6 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KFM65500.1 - 2.3e-05 24.7 0.0 0.13 12.6 0.0 3.2 2 1 0 2 2 2 2 HEAT repeats DUF3385 PF11865.8 KFM65500.1 - 0.013 15.4 0.0 0.27 11.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) Hat1_N PF10394.9 KFM65500.1 - 0.029 14.6 0.0 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 Histone acetyl transferase HAT1 N-terminus Cnd1 PF12717.7 KFM65500.1 - 0.06 13.4 2.1 0.91 9.5 0.1 3.7 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 KFM65500.1 - 0.78 9.9 4.1 2.8 8.0 0.1 3.4 3 1 1 4 4 4 0 Telomere-length maintenance and DNA damage repair FAT PF02259.23 KFM65501.1 - 8e-26 91.1 4.2 8e-26 91.1 4.2 1.9 2 0 0 2 2 2 1 FAT domain TPR_1 PF00515.28 KFM65501.1 - 0.00017 21.2 4.4 0.0073 16.1 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM65501.1 - 0.00018 21.5 4.7 0.0059 16.7 0.2 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM65501.1 - 0.00022 21.8 0.0 0.18 12.7 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM65501.1 - 0.00039 20.9 0.6 1.3 9.6 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM65501.1 - 0.0026 17.0 1.3 0.16 11.1 0.0 3.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM65501.1 - 0.0044 17.6 0.2 0.58 10.9 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFM65501.1 - 0.0051 16.8 0.9 0.27 11.2 0.1 3.0 3 1 1 4 4 4 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 KFM65501.1 - 0.0086 16.1 6.8 0.046 13.8 0.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM65501.1 - 0.024 14.3 0.7 0.17 11.6 0.1 2.7 3 0 0 3 3 3 0 TPR repeat YfiO PF13525.6 KFM65501.1 - 0.028 14.1 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein ATG_C PF09333.11 KFM65501.1 - 0.033 14.5 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain PI3_PI4_kinase PF00454.27 KFM65503.1 - 1.9e-35 122.9 0.0 2.5e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFM65503.1 - 1.2e-16 60.2 0.0 1.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 FATC domain DDE_Tnp_1_7 PF13843.6 KFM65504.1 - 2.1e-12 47.0 0.0 2.2e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 PI3K_p85B PF02192.16 KFM65504.1 - 0.0026 17.5 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain YTH PF04146.15 KFM65505.1 - 5.4e-39 133.8 0.6 1.2e-36 126.2 0.3 2.9 2 1 0 2 2 2 1 YT521-B-like domain HA2 PF04408.23 KFM65505.1 - 2.5e-20 72.8 0.0 6.8e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFM65505.1 - 2.6e-11 43.7 0.0 5.7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold NR_Repeat PF14046.6 KFM65505.1 - 0.061 13.5 3.6 7.1 6.9 1.4 2.5 2 0 0 2 2 2 0 Nuclear receptor repeat FMO-like PF00743.19 KFM65506.1 - 1.7e-87 294.1 0.1 1.9e-87 293.9 0.1 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM65506.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM65506.1 - 0.22 10.7 0.0 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFM65507.1 - 1.3e-22 79.9 0.1 1.5e-22 79.7 0.1 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM65507.1 - 2.2e-10 40.3 0.1 2.3e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM65507.1 - 0.00012 21.3 0.0 0.00014 21.2 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KFM65507.1 - 0.00021 20.6 0.0 0.00023 20.5 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NSP10 PF09401.10 KFM65507.1 - 0.017 15.1 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Peptidase_M17_N PF02789.17 KFM65507.1 - 0.023 14.5 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DUF4746 PF15928.5 KFM65509.1 - 0.13 11.7 12.7 0.17 11.3 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF936 PF06075.12 KFM65509.1 - 5.2 5.9 23.6 5.8 5.7 23.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) HTH_Tnp_Tc3_2 PF01498.18 KFM65510.1 - 2e-16 60.0 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65510.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65511.1 - 2.4e-16 59.7 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65511.1 - 2.4e-11 43.6 0.0 3.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65512.1 - 3.4e-16 59.2 3.8 5.8e-16 58.5 2.2 2.3 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM65512.1 - 1.1e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65512.1 - 1.9e-07 30.7 1.1 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65512.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65512.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Pkinase PF00069.25 KFM65513.1 - 0.0051 16.2 0.6 0.0093 15.4 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain HTH_Tnp_Tc3_2 PF01498.18 KFM65515.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65515.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65515.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65515.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65515.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Zip PF02535.22 KFM65516.1 - 7.5e-40 137.2 1.1 2.9e-39 135.2 1.1 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter SUIM_assoc PF16619.5 KFM65517.1 - 0.18 11.9 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-H2C2_2 PF13465.6 KFM65518.1 - 1.5e-98 319.2 109.1 1.3e-09 38.1 0.3 15.1 15 0 0 15 15 15 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65518.1 - 8e-68 221.3 114.0 1.9e-06 28.0 0.3 14.1 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65518.1 - 3.6e-50 164.3 108.6 0.00022 21.8 0.3 14.1 14 0 0 14 14 14 14 C2H2-type zinc finger zf-met PF12874.7 KFM65518.1 - 3.6e-37 125.7 103.4 0.0043 17.4 2.2 14.2 14 0 0 14 14 14 14 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65518.1 - 7.5e-29 99.1 95.6 0.00068 19.6 1.5 14.5 14 1 0 14 14 14 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65518.1 - 6.2e-22 77.4 76.1 0.047 14.0 1.0 14.4 14 0 0 14 14 14 11 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM65518.1 - 4.4e-14 51.9 75.3 0.0016 18.2 0.2 14.2 14 0 0 14 14 14 8 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM65518.1 - 6.6e-08 32.5 38.9 7.7 6.7 0.1 13.4 13 1 1 14 14 14 1 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM65518.1 - 6.2e-06 25.9 20.5 1.7 8.5 0.1 8.7 4 3 6 10 10 10 3 GAGA factor zf-C2H2_11 PF16622.5 KFM65518.1 - 7.9e-05 22.3 85.1 0.48 10.2 1.7 13.5 14 0 0 14 14 14 5 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFM65518.1 - 0.00014 22.5 55.1 0.9 10.3 1.3 7.3 1 1 5 7 7 7 4 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM65518.1 - 0.00017 21.7 59.1 0.71 10.0 11.0 6.1 1 1 5 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type zf-MYST PF17772.1 KFM65518.1 - 0.0002 20.9 69.5 0.69 9.6 0.6 13.1 7 4 7 14 14 14 5 MYST family zinc finger domain BolA PF01722.18 KFM65518.1 - 0.00032 20.9 22.7 11 6.4 0.5 8.3 2 2 8 10 10 10 0 BolA-like protein zf-C2H2_9 PF16293.5 KFM65518.1 - 0.00057 19.7 57.0 1.2 9.0 0.1 12.7 7 3 7 14 14 14 3 C2H2 type zinc-finger (1 copy) C1_1 PF00130.22 KFM65518.1 - 0.0034 17.2 75.9 0.18 11.7 7.6 11.6 3 2 7 10 10 10 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 KFM65518.1 - 0.011 15.8 54.4 14 5.9 0.2 13.6 14 0 0 14 14 14 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KFM65518.1 - 0.012 15.9 99.2 4.3 7.7 1.6 13.3 1 1 11 12 12 12 0 C2H2 type zinc-finger (2 copies) DUF952 PF06108.12 KFM65518.1 - 0.032 14.2 1.2 5.4 7.1 0.0 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF952) Zf_RING PF16744.5 KFM65518.1 - 0.28 11.3 68.1 12 6.1 0.2 13.3 1 1 11 12 12 12 0 KIAA1045 RING finger IGPD PF00475.18 KFM65518.1 - 0.42 10.9 7.2 1.8 8.8 0.6 4.0 3 1 1 4 4 4 0 Imidazoleglycerol-phosphate dehydratase zf-H2C2_2 PF13465.6 KFM65519.1 - 7.2e-99 320.2 124.0 7e-09 35.7 1.0 17.1 17 0 0 17 17 17 17 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65519.1 - 8.8e-72 233.8 135.9 2.1e-07 31.0 1.3 16.2 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65519.1 - 5.4e-52 169.9 130.8 0.00033 21.3 1.1 16.2 16 0 0 16 16 16 16 C2H2-type zinc finger zf-met PF12874.7 KFM65519.1 - 7.1e-35 118.4 118.9 0.00099 19.4 1.3 16.8 15 1 1 16 16 16 14 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65519.1 - 7.3e-28 96.2 93.1 0.028 14.7 0.3 16.5 15 1 1 16 16 16 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM65519.1 - 3.1e-23 81.2 113.9 0.0014 18.6 0.8 16.5 16 1 0 16 16 16 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM65519.1 - 1.3e-21 76.0 87.3 0.015 15.1 0.2 16.6 16 0 0 16 16 16 11 C2H2-type zinc-finger domain zf-RRPl_C4 PF17026.5 KFM65519.1 - 1.5e-07 31.5 65.7 0.058 13.5 5.7 7.0 1 1 5 6 6 6 6 Putative ribonucleoprotein zinc-finger pf C4 type GAGA PF09237.11 KFM65519.1 - 1.7e-07 30.9 22.3 0.074 12.9 0.1 9.5 3 3 9 13 13 12 1 GAGA factor zf-C2H2_9 PF16293.5 KFM65519.1 - 1.7e-06 27.7 68.4 2.3 8.1 0.2 15.0 6 4 10 16 16 16 5 C2H2 type zinc-finger (1 copy) Tox-HNH-HHH PF15637.6 KFM65519.1 - 7.2e-05 22.9 7.0 2.6 8.3 0.1 5.9 1 1 4 7 7 7 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-DBF PF07535.12 KFM65519.1 - 0.00016 21.7 67.7 11 6.3 0.7 15.0 14 1 1 15 15 15 0 DBF zinc finger zf-C2H2_11 PF16622.5 KFM65519.1 - 0.00023 20.8 102.7 0.14 12.0 2.7 14.8 16 0 0 16 16 16 6 zinc-finger C2H2-type DUF952 PF06108.12 KFM65519.1 - 0.00031 20.7 3.8 15 5.7 0.1 6.1 1 1 4 7 7 7 0 Protein of unknown function (DUF952) BolA PF01722.18 KFM65519.1 - 0.0013 19.0 32.2 3.4 8.0 1.7 9.0 2 1 6 9 9 9 2 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM65519.1 - 0.0024 17.9 49.3 2.8 8.1 0.0 13.8 14 2 2 16 16 16 2 Sec23/Sec24 zinc finger zinc_ribbon_15 PF17032.5 KFM65519.1 - 0.0031 18.2 63.4 2.4 9.0 1.4 8.5 2 1 8 10 10 10 1 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM65519.1 - 0.0043 17.4 118.4 1.1 9.6 0.8 15.4 1 1 13 14 14 14 4 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM65519.1 - 0.008 16.3 66.7 23 5.2 0.2 15.5 16 0 0 16 16 16 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFM65519.1 - 0.0083 15.7 0.8 0.0083 15.7 0.8 14.6 9 3 7 16 16 16 3 MYST family zinc finger domain FERM_F1 PF18379.1 KFM65519.1 - 0.027 14.5 2.7 9.5 6.3 0.0 4.5 3 2 2 5 5 5 0 FERM F1 ubiquitin-like domain C1_1 PF00130.22 KFM65519.1 - 0.14 12.0 92.4 1.6 8.7 4.6 14.1 3 2 11 14 14 14 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 KFM65519.1 - 0.36 10.8 60.1 2.9 7.9 0.3 12.8 14 0 0 14 14 13 0 zinc-finger of a C2HC-type FYVE PF01363.21 KFM65519.1 - 5 7.3 83.6 3.1 8.0 8.9 8.0 1 1 4 5 5 3 0 FYVE zinc finger Scramblase PF03803.15 KFM65519.1 - 9.4 5.5 10.8 0.27 10.5 1.2 2.9 3 1 0 3 3 3 0 Scramblase RabGAP-TBC PF00566.18 KFM65520.1 - 1.8e-37 129.1 0.4 4.9e-37 127.7 0.4 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4682 PF15733.5 KFM65520.1 - 5.9e-14 52.7 1.7 1.4e-13 51.5 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4682) DASH_Hsk3 PF08227.11 KFM65520.1 - 0.39 11.1 2.2 0.52 10.7 0.3 2.1 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DDE_3 PF13358.6 KFM65521.1 - 0.027 14.2 0.3 0.036 13.8 0.3 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF5641 PF18701.1 KFM65522.1 - 5.3e-24 84.2 0.0 7.3e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) HSP70 PF00012.20 KFM65523.1 - 5.1e-18 64.6 0.1 5.4e-18 64.5 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein BDV_P10 PF06515.11 KFM65524.1 - 0.014 15.4 0.0 0.053 13.6 0.0 2.0 1 0 0 1 1 1 0 Borna disease virus P10 protein BSD PF03909.17 KFM65524.1 - 1.7 8.7 6.9 1.6 8.8 0.3 3.9 3 0 0 3 3 3 0 BSD domain Spc7 PF08317.11 KFM65524.1 - 2.1 7.2 107.3 1.2 7.9 27.2 6.1 3 2 3 6 6 6 0 Spc7 kinetochore protein 7tm_1 PF00001.21 KFM65525.1 - 1.5e-18 67.1 3.9 1.7e-18 66.9 3.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Sru PF10322.9 KFM65525.1 - 9.2e-05 21.9 1.8 0.00012 21.5 1.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru 7TM_GPCR_Srv PF10323.9 KFM65525.1 - 0.00035 20.0 0.5 0.00039 19.9 0.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF2189 PF09955.9 KFM65525.1 - 0.00045 20.5 0.7 0.00067 19.9 0.7 1.3 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2189) AveC_like PF17198.4 KFM65525.1 - 0.01 15.3 1.0 0.013 15.0 1.0 1.2 1 0 0 1 1 1 0 Spirocyclase AveC-like DHHC PF01529.20 KFM65525.1 - 0.011 15.9 0.9 0.016 15.3 0.9 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase PRA1 PF03208.19 KFM65525.1 - 0.03 13.9 1.5 0.05 13.2 1.5 1.2 1 0 0 1 1 1 0 PRA1 family protein DUF4079 PF13301.6 KFM65525.1 - 0.067 13.3 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Orf78 PF06024.12 KFM65525.1 - 1.8 8.9 3.4 1.1 9.6 0.2 2.0 1 1 1 2 2 2 0 Orf78 (ac78) DUF2852 PF11014.8 KFM65525.1 - 8.2 6.6 5.4 1.9 8.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DDE_1 PF03184.19 KFM65526.1 - 5.2e-50 169.5 0.1 1.1e-49 168.4 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.13 KFM65526.1 - 8.6e-16 57.3 1.5 2.7e-15 55.7 1.5 1.9 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 KFM65526.1 - 3e-12 46.4 0.0 2.1e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 KFM65526.1 - 1e-05 25.5 0.0 3.6e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM65526.1 - 0.0067 16.5 0.1 0.017 15.2 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KFM65527.1 - 2.1e-16 59.9 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65527.1 - 7.6e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SNF2_N PF00176.23 KFM65528.1 - 5.2e-62 209.6 1.0 7.2e-62 209.1 1.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM65528.1 - 3e-19 69.4 0.0 5.7e-18 65.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM65528.1 - 1.2e-11 44.9 0.0 9.5e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFM65528.1 - 2.7e-07 30.0 2.1 0.00077 18.7 0.5 2.6 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KFM65528.1 - 4.8e-06 26.4 0.0 1.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KFM65528.1 - 0.00023 20.5 0.1 0.00054 19.2 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase TEX12 PF15219.6 KFM65528.1 - 0.018 15.3 0.4 0.08 13.3 0.1 2.2 2 0 0 2 2 1 0 Testis-expressed 12 AAA_34 PF13872.6 KFM65528.1 - 0.025 13.5 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DUF2075 PF09848.9 KFM65528.1 - 0.035 13.3 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD_2 PF06733.15 KFM65528.1 - 0.055 13.1 0.8 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 DEAD_2 KRBA1 PF15287.6 KFM65528.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 KRBA1 family repeat HHH_3 PF12836.7 KFM65529.1 - 0.0034 17.6 0.0 0.025 14.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif Ribosomal_60s PF00428.19 KFM65529.1 - 0.91 10.2 3.6 0.8 10.3 0.2 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Coilin_N PF15862.5 KFM65529.1 - 5.6 6.8 18.2 0.2 11.5 6.2 2.9 2 0 0 2 2 2 0 Coilin N-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM65530.1 - 5.3e-16 58.6 3.5 6.1e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65530.1 - 1.4e-13 50.9 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65530.1 - 3.1e-07 30.1 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65530.1 - 0.0028 17.4 0.6 0.008 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM65530.1 - 0.03 14.5 0.4 0.096 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM65530.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM65533.1 - 1.6e-13 50.7 0.0 2.1e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TSP_1 PF00090.19 KFM65534.1 - 4.1e-08 33.3 5.3 4.1e-08 33.3 5.3 2.7 3 0 0 3 3 3 1 Thrombospondin type 1 domain Somatomedin_B PF01033.17 KFM65534.1 - 5.1e-07 30.0 10.5 5.1e-07 30.0 10.5 5.1 5 0 0 5 5 5 2 Somatomedin B domain MTS_N PF08468.11 KFM65534.1 - 0.00022 21.3 0.1 0.00038 20.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain N-terminal Cob_adeno_trans PF01923.18 KFM65535.1 - 1.1e-58 198.0 0.0 1.3e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase SesA PF17107.5 KFM65535.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases LRR_8 PF13855.6 KFM65536.1 - 3.5e-24 84.3 12.7 8.7e-11 41.4 0.9 5.5 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KFM65536.1 - 2.7e-15 56.2 30.3 2.1e-07 31.1 2.7 6.5 4 1 1 7 7 7 4 Leucine Rich repeats (2 copies) B3_4 PF03483.17 KFM65536.1 - 3.8e-10 39.7 0.1 9.3e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 B3/4 domain LRR_6 PF13516.6 KFM65536.1 - 4.2e-06 26.4 17.5 0.26 11.5 0.0 6.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KFM65536.1 - 0.0021 18.3 21.1 1.9 9.4 0.0 7.5 9 0 0 9 9 9 2 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 KFM65536.1 - 0.081 13.0 0.0 18 5.5 0.0 3.1 2 0 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain INTS2 PF14750.6 KFM65537.1 - 0 1551.8 17.3 0 1551.5 17.3 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 STPPase_N PF16891.5 KFM65537.1 - 0.041 14.3 0.5 10 6.7 0.1 4.0 4 0 0 4 4 4 0 Serine-threonine protein phosphatase N-terminal domain UIM PF02809.20 KFM65539.1 - 2.3e-05 24.0 35.6 0.0021 17.8 3.6 4.6 5 0 0 5 5 5 3 Ubiquitin interaction motif RAP80_UIM PF18282.1 KFM65539.1 - 0.0024 17.6 14.8 0.26 11.1 8.9 2.3 2 0 0 2 2 2 2 RAP80 N-terminal ubiquitin interaction motif ADPrib_exo_Tox PF03496.14 KFM65539.1 - 0.024 14.0 0.3 0.029 13.7 0.3 1.1 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme RGS-like PF09128.11 KFM65539.1 - 0.082 12.6 3.4 0.088 12.5 3.4 1.0 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Pkinase PF00069.25 KFM65540.1 - 2.3e-25 89.5 0.0 2.5e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65540.1 - 1.8e-14 53.7 0.0 2e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM65540.1 - 0.0001 21.7 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Arg_decarbox_C PF17944.1 KFM65540.1 - 0.16 12.5 0.3 0.39 11.3 0.2 1.6 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension RPE65 PF03055.15 KFM65541.1 - 7.1e-23 81.5 0.0 7.5e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein BTB PF00651.31 KFM65543.1 - 2e-39 134.3 0.8 1.9e-26 92.5 0.3 2.8 3 0 0 3 3 3 2 BTB/POZ domain BACK PF07707.15 KFM65543.1 - 2e-05 24.6 1.6 0.0019 18.3 0.5 3.0 3 0 0 3 3 3 2 BTB And C-terminal Kelch DDE_1 PF03184.19 KFM65545.1 - 1e-29 103.4 0.1 1.7e-29 102.7 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease ErmC PF06308.11 KFM65545.1 - 0.022 15.1 0.2 0.043 14.2 0.2 1.4 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) Ada3 PF10198.9 KFM65545.1 - 0.038 14.1 1.3 0.093 12.9 0.2 2.2 3 0 0 3 3 3 0 Histone acetyltransferases subunit 3 AcetylCoA_hydro PF02550.15 KFM65545.1 - 0.074 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain DUF4371 PF14291.6 KFM65546.1 - 2.8e-10 40.2 0.1 1e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM65546.1 - 0.0024 17.4 0.9 0.0024 17.4 0.9 2.4 2 1 0 2 2 2 1 Zinc-finger C2H2-type BTB PF00651.31 KFM65547.1 - 6.9e-29 100.3 0.1 1.9e-15 57.0 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain Skp1_POZ PF03931.15 KFM65547.1 - 0.067 13.4 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Mitochondr_Som1 PF11093.8 KFM65547.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial export protein Som1 DDE_3 PF13358.6 KFM65549.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 DDE superfamily endonuclease DUF410 PF04190.13 KFM65552.1 - 4.1e-57 193.9 0.1 4.9e-57 193.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Apyrase PF06079.11 KFM65553.1 - 9.6e-129 428.7 2.0 1.1e-128 428.5 2.0 1.0 1 0 0 1 1 1 1 Apyrase DUF202 PF02656.15 KFM65553.1 - 0.057 13.9 0.3 0.12 12.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) THUMP PF02926.17 KFM65554.1 - 7.5e-09 35.8 0.2 1.3e-08 35.0 0.2 1.5 1 0 0 1 1 1 1 THUMP domain IL15 PF02372.15 KFM65554.1 - 0.018 15.1 0.6 0.05 13.6 0.6 1.7 1 0 0 1 1 1 0 Interleukin 15 CHASE3 PF05227.13 KFM65554.1 - 0.12 12.3 0.3 0.4 10.6 0.3 1.9 1 1 0 1 1 1 0 CHASE3 domain Ank_4 PF13637.6 KFM65555.1 - 1e-14 54.7 0.0 1.3e-13 51.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM65555.1 - 6.9e-11 42.6 0.0 1.4e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM65555.1 - 1.5e-10 41.1 0.1 3.8e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM65555.1 - 2e-09 37.5 0.1 5e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFM65555.1 - 2.2e-09 36.7 0.0 2.8e-06 27.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ribosomal_L1 PF00687.21 KFM65556.1 - 1.6e-44 152.1 1.5 1.6e-44 152.1 1.5 3.3 2 1 1 3 3 3 1 Ribosomal protein L1p/L10e family LNS2 PF08235.13 KFM65557.1 - 2.6e-94 314.9 0.0 5.9e-94 313.8 0.0 1.6 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KFM65557.1 - 1e-45 153.9 0.1 2.2e-45 152.8 0.1 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KFM65557.1 - 7.2e-31 106.3 0.0 2e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Cadherin-like PF12733.7 KFM65557.1 - 0.85 10.2 5.0 30 5.2 2.3 3.0 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain Polysacc_deac_1 PF01522.21 KFM65558.1 - 3.4e-08 33.4 0.1 1.8e-07 31.1 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide deacetylase PBP1_TM PF14812.6 KFM65558.1 - 0.039 14.3 8.1 0.76 10.2 1.7 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CathepsinC_exc PF08773.11 KFM65558.1 - 0.04 14.2 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Cathepsin C exclusion domain DUF3439 PF11921.8 KFM65558.1 - 0.11 12.5 5.2 0.3 11.1 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 KFM65558.1 - 9.6 6.2 16.0 0.047 13.7 6.3 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Piwi PF02171.17 KFM65560.1 - 2.2e-78 263.6 0.0 4.6e-78 262.5 0.0 1.5 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KFM65560.1 - 6e-15 55.2 0.6 6e-15 55.2 0.6 2.1 3 0 0 3 3 3 1 PAZ domain ArgoN PF16486.5 KFM65560.1 - 2.5e-14 54.1 0.2 8.6e-14 52.3 0.2 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFM65560.1 - 1.6e-09 37.3 0.1 3.6e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KFM65560.1 - 5.7e-06 26.5 1.3 2.1e-05 24.7 0.5 2.4 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 KFM65560.1 - 0.00062 20.1 0.0 0.0018 18.6 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain Filamin PF00630.19 KFM65561.1 - 3e-101 333.2 18.7 2.4e-19 70.1 0.1 6.3 6 0 0 6 6 6 6 Filamin/ABP280 repeat CH PF00307.31 KFM65561.1 - 2.2e-42 143.7 0.7 1.8e-23 82.8 0.3 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Big_3_5 PF16640.5 KFM65561.1 - 1.4e-05 25.2 3.8 6.6 7.0 0.0 5.8 6 0 0 6 6 6 1 Bacterial Ig-like domain (group 3) Invasin_D3 PF09134.10 KFM65561.1 - 3.6e-05 24.0 0.1 3 8.2 0.0 4.9 5 0 0 5 5 5 1 Invasin, domain 3 CAMSAP_CH PF11971.8 KFM65561.1 - 8.4e-05 22.3 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain YtkA PF13115.6 KFM65561.1 - 0.0017 18.9 0.2 62 4.3 0.0 4.9 5 0 0 5 5 5 0 YtkA-like CH_2 PF06294.11 KFM65561.1 - 0.012 15.8 0.2 4.8 7.4 0.0 2.4 2 0 0 2 2 2 0 CH-like domain in sperm protein TraK PF06586.11 KFM65561.1 - 0.013 15.3 0.7 4.3 7.0 0.2 2.2 2 0 0 2 2 2 0 TraK protein Y_Y_Y PF07495.13 KFM65561.1 - 0.22 11.5 2.7 4.4 7.3 0.0 3.6 4 1 0 4 4 4 0 Y_Y_Y domain Filamin PF00630.19 KFM65562.1 - 1.1e-197 642.9 33.5 5.1e-21 75.4 0.0 13.2 13 0 0 13 13 13 13 Filamin/ABP280 repeat Big_3_5 PF16640.5 KFM65562.1 - 4.7e-14 52.3 16.0 0.021 15.0 3.4 9.2 9 0 0 9 9 9 3 Bacterial Ig-like domain (group 3) Y_Y_Y PF07495.13 KFM65562.1 - 1.4e-13 50.6 1.4 0.23 11.4 0.1 8.7 10 0 0 10 10 9 2 Y_Y_Y domain DUF5060 PF16586.5 KFM65562.1 - 4.9e-06 26.8 0.0 59 4.1 0.0 8.2 11 0 0 11 11 9 0 Domain of unknown function (DUF5060) CarboxypepD_reg PF13620.6 KFM65562.1 - 6.7e-06 26.3 12.2 0.086 13.1 0.1 6.2 5 1 0 5 5 5 2 Carboxypeptidase regulatory-like domain Invasin_D3 PF09134.10 KFM65562.1 - 1.8e-05 25.0 14.9 0.67 10.3 1.0 7.5 8 0 0 8 8 7 2 Invasin, domain 3 YtkA PF13115.6 KFM65562.1 - 0.00042 20.9 6.4 50 4.6 0.0 8.1 7 1 2 9 9 9 0 YtkA-like PKD PF00801.20 KFM65562.1 - 0.005 16.7 4.2 26 4.8 0.1 6.8 7 1 0 7 7 7 0 PKD domain SH2 PF00017.24 KFM65562.1 - 0.015 15.4 0.2 1.8 8.7 0.1 3.6 3 0 0 3 3 3 0 SH2 domain Wzt_C PF14524.6 KFM65562.1 - 0.018 15.1 0.7 15 5.6 0.0 4.1 4 0 0 4 4 4 0 Wzt C-terminal domain CopC PF04234.12 KFM65562.1 - 0.018 16.0 2.7 63 4.7 0.0 6.6 6 1 1 7 7 6 0 CopC domain DUF3568 PF12092.8 KFM65562.1 - 0.032 14.3 0.0 66 3.6 0.1 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3568) PBP5_C PF07943.13 KFM65562.1 - 0.047 13.9 0.2 17 5.7 0.0 3.4 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain Big_6 PF17936.1 KFM65562.1 - 0.3 11.4 0.0 0.3 11.4 0.0 6.8 8 2 1 9 9 6 0 Bacterial Ig domain Lipoprotein_17 PF04200.12 KFM65562.1 - 0.45 10.9 9.0 14 6.1 0.1 5.4 4 1 1 5 5 5 0 Lipoprotein associated domain EMP24_GP25L PF01105.24 KFM65562.1 - 0.66 9.9 9.0 40 4.1 1.1 5.8 7 2 0 8 8 8 0 emp24/gp25L/p24 family/GOLD DUF4397 PF14344.6 KFM65562.1 - 0.81 10.5 5.5 11 6.9 0.0 4.9 4 1 2 6 6 6 0 Domain of unknown function (DUF4397) DUF4493 PF14900.6 KFM65562.1 - 0.82 9.5 16.8 1.7 8.5 2.8 5.0 5 1 0 5 5 5 0 Domain of unknown function (DUF4493) zf-H2C2_2 PF13465.6 KFM65563.1 - 1.1e-99 322.7 107.4 3.3e-09 36.7 0.3 16.1 16 0 0 16 16 16 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65563.1 - 7e-71 230.9 126.1 2.2e-06 27.8 1.9 15.3 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65563.1 - 2.5e-55 180.3 115.0 0.00034 21.2 1.6 15.2 15 0 0 15 15 15 15 C2H2-type zinc finger zf-met PF12874.7 KFM65563.1 - 4.1e-29 100.1 114.4 0.00037 20.8 2.7 15.5 15 0 0 15 15 15 13 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65563.1 - 2.2e-25 88.3 103.3 0.0047 17.2 0.2 15.2 14 1 1 15 15 15 14 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM65563.1 - 8e-25 86.3 115.5 0.00013 21.9 1.7 16.1 15 2 0 15 15 15 13 C2H2-type zinc finger GAGA PF09237.11 KFM65563.1 - 2.7e-07 30.3 28.4 0.03 14.1 0.9 8.1 3 2 6 9 9 9 3 GAGA factor BolA PF01722.18 KFM65563.1 - 0.00013 22.2 19.2 0.87 9.9 0.2 7.5 3 2 5 8 8 8 3 BolA-like protein zf_UBZ PF18439.1 KFM65563.1 - 0.00041 19.9 65.9 0.39 10.3 0.1 14.0 15 0 0 15 15 15 5 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM65563.1 - 0.00063 19.6 60.8 1 9.3 0.2 14.6 15 0 0 15 15 15 4 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFM65563.1 - 0.0023 18.2 94.2 2.9 8.3 5.5 12.1 1 1 9 11 11 11 5 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM65563.1 - 0.003 17.5 47.8 0.68 10.0 1.4 9.7 4 3 5 9 9 9 4 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KFM65563.1 - 0.005 16.8 60.8 3 8.0 1.3 13.4 14 1 1 15 15 15 3 Sec23/Sec24 zinc finger DUF4764 PF15961.5 KFM65563.1 - 0.085 11.5 0.2 0.085 11.5 0.2 7.2 1 1 7 8 8 8 0 Domain of unknown function (DUF4764) zinc_ribbon_15 PF17032.5 KFM65563.1 - 0.7 10.7 68.5 2.6 8.9 2.6 8.4 2 2 7 9 9 9 0 zinc-ribbon family DAGAT PF03982.13 KFM65564.1 - 0.055 12.4 0.0 0.055 12.4 0.0 1.0 1 0 0 1 1 1 0 Diacylglycerol acyltransferase zf-H2C2_2 PF13465.6 KFM65567.1 - 7.2e-101 326.5 99.7 6.6e-08 32.6 0.4 16.1 16 0 0 16 16 16 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65567.1 - 1.9e-74 242.2 136.6 3.2e-06 27.3 1.2 16.1 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65567.1 - 4.1e-53 173.4 126.8 0.00036 21.1 1.6 16.1 16 0 0 16 16 16 15 C2H2-type zinc finger zf-met PF12874.7 KFM65567.1 - 1.9e-34 117.0 128.8 0.0035 17.7 2.0 16.3 16 0 0 16 16 16 14 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65567.1 - 1.1e-26 92.5 100.5 0.0042 17.3 0.9 16.4 15 1 1 16 16 16 13 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM65567.1 - 7.4e-25 86.4 115.6 0.021 14.9 1.0 16.6 16 1 0 16 16 16 14 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM65567.1 - 7.4e-08 32.1 57.9 5.3 7.1 0.1 14.7 15 0 0 15 15 15 3 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM65567.1 - 0.012 15.7 67.9 0.15 12.1 7.6 6.6 1 1 6 7 7 7 0 Putative ribonucleoprotein zinc-finger pf C4 type Flag1_repress PF03614.13 KFM65567.1 - 0.034 13.9 11.3 0.54 10.0 0.4 4.0 2 2 2 4 4 4 0 Repressor of phase-1 flagellin PriA_CRR PF18319.1 KFM65567.1 - 0.054 13.5 0.3 0.054 13.5 0.3 10.5 15 0 0 15 15 14 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2H2_2 PF12756.7 KFM65567.1 - 0.073 13.4 99.0 0.77 10.1 11.1 11.9 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM65567.1 - 5.8 7.7 69.3 2.5 8.9 0.6 8.1 2 2 6 9 9 9 0 zinc-ribbon family zf-H2C2_2 PF13465.6 KFM65568.1 - 1.3e-51 170.8 58.4 7.4e-08 32.5 2.2 8.1 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65568.1 - 1.6e-32 110.1 71.8 2.6e-06 27.6 1.7 8.2 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65568.1 - 2.6e-21 74.5 66.9 0.0006 20.4 1.7 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.7 KFM65568.1 - 3.3e-16 59.1 63.5 0.0019 18.5 2.4 7.7 8 0 0 8 8 7 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65568.1 - 1.5e-12 47.2 62.5 0.0004 20.3 0.6 8.9 8 1 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65568.1 - 5.4e-12 45.7 45.0 0.0024 18.1 0.9 8.0 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM65568.1 - 6.8e-07 29.0 27.5 4.1 7.4 0.1 8.3 8 0 0 8 8 8 3 zinc-finger of a C2HC-type C1_1 PF00130.22 KFM65568.1 - 2.4e-05 24.1 41.4 0.091 12.7 3.4 6.8 2 2 4 6 6 6 5 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.7 KFM65568.1 - 0.0015 18.8 47.0 1.9 8.9 2.0 6.1 1 1 5 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM65568.1 - 0.0023 18.0 32.7 0.54 10.4 8.2 4.0 1 1 3 4 4 4 4 Putative ribonucleoprotein zinc-finger pf C4 type BolA PF01722.18 KFM65568.1 - 0.019 15.2 10.7 9.2 6.6 0.1 4.8 1 1 3 4 4 4 0 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM65568.1 - 0.05 13.7 26.5 3.8 7.6 0.1 7.0 7 1 1 8 8 7 0 Sec23/Sec24 zinc finger zf_UBZ PF18439.1 KFM65568.1 - 0.053 13.1 32.9 1.9 8.1 0.1 7.9 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 KFM65568.1 - 0.43 10.7 29.1 16 5.7 0.1 7.7 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Zf_RING PF16744.5 KFM65568.1 - 0.45 10.7 36.4 12 6.1 5.1 7.1 1 1 6 7 7 7 0 KIAA1045 RING finger FYVE PF01363.21 KFM65568.1 - 0.87 9.8 43.7 2.3 8.4 10.2 4.4 1 1 3 4 4 4 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM65568.1 - 2 9.2 33.1 4.2 8.2 3.0 4.1 1 1 3 4 4 4 0 zinc-ribbon family zf-H2C2_2 PF13465.6 KFM65569.1 - 1.2e-33 114.0 33.9 1e-09 38.4 0.1 6.1 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65569.1 - 1.2e-25 88.4 40.1 5.7e-06 26.5 0.6 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65569.1 - 1.2e-21 75.5 34.1 0.00036 21.1 0.7 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM65569.1 - 4.5e-16 58.6 32.0 0.0023 18.3 0.4 5.4 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65569.1 - 1.2e-13 50.7 27.8 0.00026 20.9 0.2 6.0 5 1 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65569.1 - 1.4e-11 44.4 33.6 0.056 13.7 0.7 5.6 3 1 3 6 6 6 5 Zinc-finger double-stranded RNA-binding C5HCH PF17982.1 KFM65569.1 - 4e-05 23.7 16.9 0.096 12.9 2.7 4.8 3 1 2 5 5 5 2 NSD Cys-His rich domain zf-C2HC_2 PF13913.6 KFM65569.1 - 9.1e-05 22.3 20.5 0.25 11.3 0.4 5.3 5 0 0 5 5 5 2 zinc-finger of a C2HC-type GAGA PF09237.11 KFM65569.1 - 0.00025 20.8 11.9 0.0025 17.6 0.1 4.4 1 1 4 5 5 5 1 GAGA factor zf-C2H2_2 PF12756.7 KFM65569.1 - 0.00032 21.0 32.6 0.62 10.4 1.8 5.0 1 1 4 5 5 5 3 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM65569.1 - 0.00069 19.2 22.1 0.039 13.6 1.3 5.2 4 1 1 5 5 5 2 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 KFM65569.1 - 0.00088 19.2 12.7 14 5.7 0.1 5.1 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 zf-Sec23_Sec24 PF04810.15 KFM65569.1 - 0.0014 18.6 13.0 0.83 9.8 0.8 5.0 5 0 0 5 5 5 1 Sec23/Sec24 zinc finger FYVE PF01363.21 KFM65569.1 - 0.0069 16.5 22.5 0.59 10.3 12.0 3.8 1 1 2 3 3 3 2 FYVE zinc finger DUF2256 PF10013.9 KFM65569.1 - 0.015 15.4 13.5 16 5.7 0.0 5.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFM65569.1 - 0.051 13.2 19.3 3 7.5 0.6 5.0 1 1 4 5 5 5 0 MYST family zinc finger domain Zf_RING PF16744.5 KFM65569.1 - 0.053 13.6 17.5 15 5.7 2.0 4.9 1 1 4 5 5 5 0 KIAA1045 RING finger zf-RRPl_C4 PF17026.5 KFM65569.1 - 0.085 13.0 13.3 0.078 13.1 7.6 2.3 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Rpr2 PF04032.16 KFM65569.1 - 0.091 13.1 16.9 5.4 7.4 11.7 3.3 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_15 PF17032.5 KFM65569.1 - 0.1 13.4 14.4 4.1 8.2 0.5 3.0 1 1 1 2 2 2 0 zinc-ribbon family BolA PF01722.18 KFM65569.1 - 0.27 11.6 6.7 9.1 6.6 0.0 3.8 1 1 2 4 4 4 0 BolA-like protein zf-HIT PF04438.16 KFM65569.1 - 0.3 11.0 18.7 5.4 7.0 0.2 5.0 5 0 0 5 5 5 0 HIT zinc finger XPA_N PF01286.18 KFM65569.1 - 0.47 10.5 12.5 25 5.0 0.1 4.9 5 0 0 5 5 5 0 XPA protein N-terminal Cript PF10235.9 KFM65569.1 - 0.96 10.1 13.9 0.48 11.0 1.3 3.6 1 1 2 3 3 3 0 Microtubule-associated protein CRIPT zf_ZIC PF18366.1 KFM65569.1 - 1.1 9.4 19.5 2.4 8.3 0.7 4.9 1 1 4 5 5 5 0 Zic proteins zinc finger domain UBZ_FAAP20 PF15750.5 KFM65569.1 - 1.3 9.0 13.0 11 6.0 0.4 4.8 5 0 0 5 5 5 0 Ubiquitin-binding zinc-finger zf-met2 PF12907.7 KFM65569.1 - 1.4 9.2 19.7 2.6 8.3 1.0 5.3 5 0 0 5 5 5 0 Zinc-binding zf-C2H2_9 PF16293.5 KFM65569.1 - 1.5 8.8 21.7 14 5.6 1.3 4.9 1 1 4 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 KFM65569.1 - 1.6 8.8 34.5 3.9 7.6 2.4 5.1 1 1 4 5 5 5 0 BED zinc finger Endonuclease_7 PF02945.15 KFM65569.1 - 2 8.4 25.5 0.24 11.3 8.2 3.5 1 1 3 4 4 4 0 Recombination endonuclease VII Acyltransferase PF01553.21 KFM65570.1 - 3.6e-09 36.3 0.0 1.1e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 KFM65570.1 - 0.00023 20.2 0.0 0.00043 19.3 0.0 1.6 1 1 0 1 1 1 1 Diacylglycerol acyltransferase HTH_Tnp_Tc3_2 PF01498.18 KFM65571.1 - 1.4e-17 63.7 1.3 5.7e-16 58.5 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65571.1 - 1.4e-13 50.9 0.0 2.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65572.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65572.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65572.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65572.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65572.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF3504 PF12012.8 KFM65575.1 - 3.2e-11 43.4 0.1 1.4e-09 38.1 0.1 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3504) zf-FCS PF06467.14 KFM65575.1 - 0.00017 21.5 1.9 0.00017 21.5 1.9 2.1 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif VATC PF18716.1 KFM65575.1 - 0.061 13.2 2.5 0.27 11.1 2.5 2.0 1 1 0 1 1 1 0 Vms1-associating treble clef domain Lig_C PF18330.1 KFM65575.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region PLATZ PF04640.14 KFM65575.1 - 0.36 11.5 1.8 0.64 10.7 0.8 2.0 2 0 0 2 2 2 0 PLATZ transcription factor HTH_48 PF17906.1 KFM65576.1 - 1.4e-06 28.3 1.1 1.4e-06 28.3 1.1 1.9 2 0 0 2 2 2 1 HTH domain in Mos1 transposase SPA PF08616.10 KFM65577.1 - 4.2e-09 36.4 0.1 4.7e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Stabilization of polarity axis RAM PF15320.6 KFM65577.1 - 0.0056 17.2 0.3 0.0067 17.0 0.3 1.3 1 1 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein Pkinase PF00069.25 KFM65578.1 - 1.5e-140 467.1 0.0 1.4e-71 241.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65578.1 - 5.2e-68 229.1 0.0 2.6e-33 115.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFM65578.1 - 1.5e-14 54.0 0.0 1.1e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KFM65578.1 - 2e-09 37.7 2.3 9.5e-05 22.4 0.0 4.1 2 2 2 4 4 4 3 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFM65578.1 - 2.1e-09 36.8 3.4 3.7e-05 22.8 0.2 2.3 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_fungal PF17667.1 KFM65578.1 - 2.6e-09 36.4 7.4 2.3e-06 26.6 0.0 3.9 4 1 1 5 5 5 2 Fungal protein kinase Kdo PF06293.14 KFM65578.1 - 4.4e-09 36.0 1.3 2.3e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 KFM65578.1 - 5.2e-07 30.3 3.2 5.6e-07 30.2 1.1 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain FTA2 PF13095.6 KFM65578.1 - 1.9e-06 27.7 0.5 1.3 8.6 0.0 3.4 3 0 0 3 3 3 3 Kinetochore Sim4 complex subunit FTA2 SR-25 PF10500.9 KFM65578.1 - 0.39 10.3 13.1 0.26 10.9 9.7 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ADH_zinc_N PF00107.26 KFM65579.1 - 1.2e-20 73.8 0.0 1.9e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM65579.1 - 1.7e-11 43.9 0.0 5.3e-10 39.1 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFM65579.1 - 1.9e-09 38.7 0.0 3.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YAcAr PF10686.9 KFM65579.1 - 0.15 12.0 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Dpy-30 PF05186.13 KFM65582.1 - 3.4e-12 45.8 0.3 5.3e-12 45.2 0.3 1.3 1 0 0 1 1 1 1 Dpy-30 motif Na_sulph_symp PF00939.19 KFM65583.1 - 1.7e-06 27.4 4.4 1.8e-06 27.3 4.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Git3 PF11710.8 KFM65583.1 - 0.065 13.0 0.6 0.076 12.8 0.6 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Papilloma_E5 PF03025.14 KFM65583.1 - 1 9.5 11.4 6.1 7.1 11.7 2.0 1 1 1 2 2 2 0 Papillomavirus E5 eRF1_1 PF03463.15 KFM65584.1 - 7.9e-54 181.1 0.2 1.2e-53 180.5 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KFM65584.1 - 2.4e-35 121.8 0.3 4.8e-35 120.8 0.3 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFM65584.1 - 2.5e-21 76.3 0.0 5.6e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 MFS_1 PF07690.16 KFM65585.1 - 1.3e-27 96.7 17.9 9.6e-27 93.8 17.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily HMG_box PF00505.19 KFM65586.1 - 1.3e-45 153.6 60.9 5.9e-13 49.0 9.8 6.3 6 1 0 6 6 6 5 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM65586.1 - 2.8e-21 75.9 54.9 4.3e-06 27.2 7.2 6.3 6 0 0 6 6 6 5 HMG-box domain HMG_box_5 PF14887.6 KFM65586.1 - 1.8e-06 27.8 0.6 1.8e-06 27.8 0.6 4.1 3 0 0 3 3 3 1 HMG (high mobility group) box 5 Protamine_like PF06382.11 KFM65586.1 - 0.00017 21.8 30.0 0.0027 17.9 1.1 5.6 4 1 1 5 5 5 3 Protamine and protamine like SLBP_RNA_bind PF15247.6 KFM65586.1 - 0.011 15.9 0.6 0.011 15.9 0.6 3.5 3 0 0 3 3 3 0 Histone RNA hairpin-binding protein RNA-binding domain Myb_DNA-binding PF00249.31 KFM65586.1 - 0.061 13.5 0.9 0.2 11.9 0.3 2.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain DUF3106 PF11304.8 KFM65586.1 - 0.081 13.4 37.9 0.93 10.0 0.1 6.4 6 1 0 6 6 6 0 Protein of unknown function (DUF3106) HTH_WhiA PF02650.14 KFM65586.1 - 0.25 11.7 4.7 15 6.0 0.2 3.8 2 1 1 3 3 3 0 WhiA C-terminal HTH domain RyR PF02026.16 KFM65586.1 - 6.2 7.1 20.4 3.5 7.9 0.3 5.0 4 0 0 4 4 4 0 RyR domain LPD11 PF18824.1 KFM65586.1 - 7.8 6.7 18.6 0.093 12.8 0.4 4.0 5 0 0 5 5 5 0 Large polyvalent protein-associated domain 11 Hormone_1 PF00103.20 KFM65586.1 - 9.8 5.9 12.3 0.12 12.1 0.4 3.1 3 0 0 3 3 3 0 Somatotropin hormone family YTH PF04146.15 KFM65587.1 - 2.8e-47 160.8 0.2 6.8e-47 159.5 0.2 1.7 1 0 0 1 1 1 1 YT521-B-like domain Oxidored_q2 PF00420.24 KFM65588.1 - 0.002 17.7 0.0 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Dicer_dimer PF03368.14 KFM65590.1 - 0.5 10.6 5.1 5.3 7.3 1.3 4.0 2 1 1 3 3 3 0 Dicer dimerisation domain BTB PF00651.31 KFM65591.1 - 1.9e-19 69.9 0.3 4.5e-19 68.7 0.3 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM65591.1 - 3.3e-17 62.5 3.7 1.2e-13 51.0 1.7 3.5 1 1 1 2 2 2 2 BTB And C-terminal Kelch Sushi PF00084.20 KFM65592.1 - 0.0002 21.9 0.1 0.00026 21.5 0.1 1.2 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Sushi PF00084.20 KFM65593.1 - 3.7e-13 49.9 2.0 7.9e-09 36.0 0.3 2.7 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) DUF3774 PF12609.8 KFM65593.1 - 0.24 12.4 4.5 2.6 9.1 2.3 3.2 3 1 0 3 3 3 0 Wound-induced protein VWA PF00092.28 KFM65594.1 - 5.1e-35 121.3 0.1 6.6e-35 120.9 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFM65594.1 - 3.8e-19 69.3 0.1 6e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ephrin_rec_like PF07699.13 KFM65594.1 - 4.2e-09 36.0 9.7 4.2e-09 36.0 9.7 2.8 2 0 0 2 2 2 1 Putative ephrin-receptor like Sushi PF00084.20 KFM65594.1 - 3.5e-07 30.7 5.0 3.5e-07 30.7 5.0 3.8 3 1 1 4 4 4 2 Sushi repeat (SCR repeat) DUF1194 PF06707.11 KFM65594.1 - 1.4e-06 27.6 0.0 2.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1194) VWA_3 PF13768.6 KFM65594.1 - 7.3e-05 22.7 0.0 0.00011 22.1 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFM65594.1 - 0.036 13.5 0.0 0.077 12.4 0.0 1.5 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein YjeF_N PF03853.15 KFM65594.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Ephrin_rec_like PF07699.13 KFM65595.1 - 5.4e-39 131.7 52.1 6.7e-16 57.8 2.2 5.3 4 1 0 4 4 3 3 Putative ephrin-receptor like HYR PF02494.16 KFM65595.1 - 5.1e-33 113.2 1.9 3e-19 69.1 0.2 2.9 2 0 0 2 2 2 2 HYR domain EGF PF00008.27 KFM65595.1 - 6.4e-31 106.3 101.9 8.8e-09 35.5 6.6 9.1 9 0 0 9 9 9 6 EGF-like domain Pentaxin PF00354.17 KFM65595.1 - 7e-20 71.5 0.0 1.4e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family hEGF PF12661.7 KFM65595.1 - 6.8e-18 64.6 100.6 4.3e-07 30.3 5.2 10.2 10 0 0 10 10 9 6 Human growth factor-like EGF Laminin_G_3 PF13385.6 KFM65595.1 - 5.8e-13 49.2 3.3 9.6e-13 48.5 3.3 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 KFM65595.1 - 5.8e-09 36.2 113.6 0.0021 18.4 8.9 8.6 8 0 0 8 8 8 5 EGF-like domain TNFR_c6 PF00020.18 KFM65595.1 - 1e-05 25.8 26.3 0.3 11.5 0.1 7.2 3 3 3 6 6 6 5 TNFR/NGFR cysteine-rich region EGF_CA PF07645.15 KFM65595.1 - 0.00043 20.4 14.7 0.00043 20.4 14.7 10.0 8 2 2 10 10 8 4 Calcium-binding EGF domain EGF_alliinase PF04863.13 KFM65595.1 - 0.005 17.2 5.0 0.005 17.2 5.0 7.2 5 1 1 6 6 6 1 Alliinase EGF-like domain Plasmod_Pvs28 PF06247.11 KFM65595.1 - 0.0096 16.2 8.1 0.0096 16.2 8.1 7.2 6 0 0 6 6 6 3 Pvs28 EGF domain Laminin_G_2 PF02210.24 KFM65595.1 - 0.15 12.7 0.1 0.29 11.7 0.1 1.5 1 0 0 1 1 1 0 Laminin G domain EGF_3 PF12947.7 KFM65595.1 - 4.2 7.7 75.9 0.043 14.0 9.4 7.5 4 1 2 6 6 6 0 EGF domain Aminotran_5 PF00266.19 KFM65597.1 - 5.7e-95 318.4 0.0 6.6e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFM65597.1 - 4.5e-11 42.6 0.1 7.6e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFM65597.1 - 3.5e-05 23.3 0.1 6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KFM65597.1 - 0.00026 19.9 0.0 0.00041 19.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF3217 PF11506.8 KFM65597.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) PX PF00787.24 KFM65598.1 - 4.4e-12 46.0 0.3 7.3e-12 45.3 0.3 1.3 1 0 0 1 1 1 1 PX domain Orn_Arg_deC_N PF02784.16 KFM65600.1 - 1.7e-81 273.3 0.0 2.1e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFM65600.1 - 1.4e-17 63.8 0.0 2e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain HTH_Tnp_Tc3_2 PF01498.18 KFM65602.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65602.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65602.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65602.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65602.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain BTB PF00651.31 KFM65603.1 - 4.9e-23 81.5 0.8 1.3e-22 80.1 0.8 1.8 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM65603.1 - 2.1e-10 40.6 0.2 7.3e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 BTB And C-terminal Kelch Peptidase_A17 PF05380.13 KFM65604.1 - 2.5e-33 115.4 0.1 3.1e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Pao retrotransposon peptidase C1_2 PF03107.16 KFM65606.1 - 0.15 12.4 1.1 0.17 12.2 0.3 1.5 2 0 0 2 2 2 0 C1 domain zf-H2C2_2 PF13465.6 KFM65607.1 - 2.1e-67 220.7 87.8 9.1e-10 38.5 0.9 12.7 12 1 1 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65607.1 - 2.6e-46 153.6 98.1 1e-06 28.8 0.8 11.4 12 0 0 12 12 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65607.1 - 2.8e-36 121.0 88.6 0.0016 19.1 4.2 11.8 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65607.1 - 6e-20 71.0 74.5 0.001 19.3 0.3 12.3 10 1 2 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM65607.1 - 7.1e-20 70.7 87.2 0.002 18.4 1.4 12.2 12 0 0 12 12 12 10 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65607.1 - 5.6e-08 32.6 79.6 0.0031 17.5 4.9 12.1 12 1 0 12 12 12 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM65607.1 - 2.5e-05 23.9 67.8 0.0086 15.8 0.3 10.4 10 2 0 10 10 10 5 C2H2-type zinc-finger domain BolA PF01722.18 KFM65607.1 - 3e-05 24.2 14.4 0.52 10.6 0.0 6.2 3 3 3 6 6 6 2 BolA-like protein ADK_lid PF05191.14 KFM65607.1 - 0.0012 18.8 38.8 0.95 9.5 4.6 7.7 6 2 2 8 8 8 3 Adenylate kinase, active site lid GAGA PF09237.11 KFM65607.1 - 0.009 15.8 0.9 0.009 15.8 0.9 9.2 1 1 9 11 11 11 3 GAGA factor zinc_ribbon_15 PF17032.5 KFM65607.1 - 1 10.1 49.6 0.75 10.6 2.8 6.1 1 1 5 6 6 6 0 zinc-ribbon family zf-C2HC_2 PF13913.6 KFM65607.1 - 4.6 7.3 48.0 0.37 10.7 0.2 8.9 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFM65608.1 - 2.8e-76 248.8 95.8 2.1e-09 37.4 0.4 15.4 15 0 0 15 15 15 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65608.1 - 5.2e-43 143.2 121.1 5.5e-06 26.5 0.2 14.5 16 0 0 16 16 15 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65608.1 - 2.8e-31 105.5 108.6 0.00069 20.2 0.6 13.6 15 1 0 15 15 13 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65608.1 - 3e-17 62.4 73.0 0.0062 16.8 0.1 12.9 12 1 2 14 14 13 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM65608.1 - 4.9e-16 58.5 102.8 0.0012 19.2 1.1 15.0 16 0 0 16 16 15 8 Zinc-finger of C2H2 type BolA PF01722.18 KFM65608.1 - 3.6e-11 43.2 13.4 0.3 11.4 0.3 8.0 3 1 5 8 8 8 4 BolA-like protein zf-H2C2_5 PF13909.6 KFM65608.1 - 1.6e-09 37.3 64.8 0.015 15.1 0.4 10.8 12 0 0 12 12 10 7 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM65608.1 - 4.4e-05 23.4 89.9 0.023 14.7 1.4 14.4 15 1 0 15 15 15 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM65608.1 - 0.0011 18.6 47.8 0.19 11.5 0.3 10.0 10 0 0 10 10 10 4 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFM65608.1 - 0.055 14.2 1.6 0.055 14.2 1.6 8.0 2 2 5 8 8 7 0 zinc-ribbon family BHD_1 PF10403.9 KFM65608.1 - 0.11 12.4 0.2 31 4.5 0.0 3.2 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 1 zf-C2HC_2 PF13913.6 KFM65608.1 - 1.2 9.1 0.0 1.2 9.1 0.0 10.1 12 0 0 12 12 11 0 zinc-finger of a C2HC-type zf-CHCC PF10276.9 KFM65608.1 - 6.3 7.0 23.2 53 4.0 0.0 8.4 10 0 0 10 10 9 0 Zinc-finger domain zf-H2C2_2 PF13465.6 KFM65610.1 - 4.5e-47 156.5 52.4 1.2e-08 34.9 0.1 8.1 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65610.1 - 1.8e-32 110.0 58.2 1.1e-05 25.6 2.4 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65610.1 - 4.5e-27 92.4 56.1 0.00033 21.2 0.5 7.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65610.1 - 4.6e-16 58.4 44.7 0.00089 19.2 0.2 7.3 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM65610.1 - 7.8e-12 45.2 49.3 0.0045 17.3 0.4 7.4 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM65610.1 - 1.2e-11 44.1 35.2 0.00019 21.1 0.6 7.3 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM65610.1 - 6.5e-10 39.0 35.9 0.057 13.7 1.4 7.3 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM65610.1 - 1.2e-06 28.7 10.8 0.69 10.2 0.4 5.2 1 1 2 4 4 4 3 BolA-like protein zf-C2HC_2 PF13913.6 KFM65610.1 - 2.2e-06 27.4 24.3 0.17 11.8 0.0 6.6 7 0 0 7 7 7 3 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM65610.1 - 0.00081 19.4 15.7 0.51 10.4 0.1 6.2 5 1 1 6 6 6 1 Sec23/Sec24 zinc finger zf-C2HE PF16278.5 KFM65610.1 - 0.00096 19.6 39.1 0.015 15.7 0.5 6.3 1 1 5 6 6 5 4 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 KFM65610.1 - 0.0049 17.5 23.8 0.61 10.8 1.0 6.0 2 1 4 6 6 6 1 Zinc finger C2H2-type, 3 repeats Ta0938 PF11494.8 KFM65610.1 - 0.0064 16.8 14.1 0.13 12.6 0.1 4.6 1 1 4 5 5 5 1 Ta0938 zinc_ribbon_15 PF17032.5 KFM65610.1 - 0.015 16.1 23.5 1.1 10.1 2.6 3.9 2 1 3 5 5 5 0 zinc-ribbon family DUF2256 PF10013.9 KFM65610.1 - 0.033 14.3 21.0 30 4.9 0.3 6.9 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 KFM65610.1 - 0.033 14.0 20.5 0.78 9.6 0.3 4.9 1 1 3 5 5 5 0 GAGA factor FYVE PF01363.21 KFM65610.1 - 0.068 13.3 40.0 0.69 10.1 11.6 4.8 1 1 3 4 4 4 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFM65610.1 - 0.15 12.4 40.3 3.1 8.2 0.2 6.7 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.8 KFM65610.1 - 0.2 12.0 0.4 0.2 12.0 0.4 3.8 1 1 4 5 5 5 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KFM65610.1 - 0.24 11.6 21.4 3.4 7.9 0.9 5.1 2 2 3 5 5 5 0 Zinc ribbon domain Baculo_IE-1 PF05290.11 KFM65610.1 - 0.37 10.7 19.1 3.2 7.7 0.6 4.8 1 1 4 5 5 5 0 Baculovirus immediate-early protein (IE-0) Rpr2 PF04032.16 KFM65610.1 - 1.9 8.8 26.6 30 5.0 0.9 4.2 1 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CCHC_2 PF13696.6 KFM65610.1 - 2.5 8.0 21.3 0.39 10.6 0.3 5.1 5 0 0 5 5 5 0 Zinc knuckle zf-C2H2_9 PF16293.5 KFM65610.1 - 3.3 7.6 26.4 5.4 6.9 0.1 6.1 3 2 4 7 7 7 0 C2H2 type zinc-finger (1 copy) zf-RING_11 PF17123.5 KFM65610.1 - 6.5 6.6 20.4 3.6 7.4 0.0 5.8 6 0 0 6 6 6 0 RING-like zinc finger zf-CHCC PF10276.9 KFM65610.1 - 9.3 6.4 0.0 9.3 6.4 0.0 5.4 7 0 0 7 7 7 0 Zinc-finger domain zf-H2C2_2 PF13465.6 KFM65611.1 - 2.1e-24 84.8 30.4 3e-10 40.1 1.7 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65611.1 - 1.2e-20 72.7 33.9 2.8e-06 27.5 2.9 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65611.1 - 4.4e-13 48.9 30.6 0.00046 20.8 2.3 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFM65611.1 - 6.4e-13 48.6 33.3 0.00059 20.1 2.8 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM65611.1 - 1.4e-10 40.9 22.3 0.00069 19.5 1.7 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65611.1 - 3.4e-08 33.5 25.5 0.0027 18.0 0.1 4.4 3 1 1 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM65611.1 - 6.6e-07 29.0 16.1 0.0053 16.5 0.2 4.0 4 0 0 4 4 4 3 C2H2-type zinc-finger domain GAGA PF09237.11 KFM65611.1 - 8.5e-06 25.5 6.3 0.28 11.0 0.1 4.1 1 1 3 4 4 4 2 GAGA factor ADK_lid PF05191.14 KFM65611.1 - 0.0066 16.4 9.3 0.043 13.8 2.7 3.2 2 1 1 3 3 3 1 Adenylate kinase, active site lid zf-C2HE PF16278.5 KFM65611.1 - 0.019 15.4 3.7 0.019 15.4 3.7 4.0 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 KFM65611.1 - 0.032 14.1 17.8 0.49 10.3 0.2 4.1 2 1 2 4 4 4 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 KFM65611.1 - 0.04 14.0 17.9 5.3 7.2 1.4 3.9 1 1 2 3 3 3 0 KIAA1045 RING finger zf_UBZ PF18439.1 KFM65611.1 - 0.11 12.1 12.8 0.87 9.2 0.8 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Adhesin_P1 PF03257.13 KFM65611.1 - 0.16 12.5 0.0 1.4 9.5 0.0 2.0 2 0 0 2 2 2 0 Mycoplasma adhesin P1 zf-C2H2_2 PF12756.7 KFM65611.1 - 0.37 11.2 25.3 0.6 10.5 3.8 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) TRAF6_Z2 PF18048.1 KFM65611.1 - 0.86 9.8 14.1 2.2 8.5 0.3 3.9 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-RING_2 PF13639.6 KFM65611.1 - 1.4 9.3 17.9 91 3.5 5.5 3.5 1 1 2 3 3 3 0 Ring finger domain HNH_5 PF14279.6 KFM65611.1 - 1.7 8.6 16.0 4.3 7.3 3.5 4.0 3 1 0 3 3 3 0 HNH endonuclease FYDLN_acid PF09538.10 KFM65611.1 - 1.8 9.3 6.6 9.7 6.9 0.1 3.5 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_15 PF17032.5 KFM65611.1 - 2.7 8.8 14.5 3.1 8.6 3.0 2.5 1 1 0 2 2 2 0 zinc-ribbon family PHD PF00628.29 KFM65611.1 - 3.5 7.6 17.9 2.3 8.2 9.7 3.2 1 1 0 2 2 2 0 PHD-finger zf-MYST PF17772.1 KFM65611.1 - 4.6 6.9 17.2 8.9 6.0 0.6 3.9 1 1 3 4 4 4 0 MYST family zinc finger domain LIM PF00412.22 KFM65611.1 - 6.4 7.1 17.6 44 4.4 9.1 3.4 1 1 1 2 2 2 0 LIM domain DUF2256 PF10013.9 KFM65611.1 - 9.5 6.4 14.6 9.1 6.5 0.1 4.1 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) RVT_1 PF00078.27 KFM65612.1 - 4.6e-09 36.1 0.0 9.8e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vpu PF00558.19 KFM65612.1 - 0.056 13.2 0.5 0.15 11.9 0.5 1.7 1 0 0 1 1 1 0 Vpu protein HTH_Tnp_Tc3_2 PF01498.18 KFM65613.1 - 5.9e-15 55.3 6.5 1e-14 54.5 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM65613.1 - 0.00042 20.9 1.6 0.00042 20.9 1.6 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM65613.1 - 0.011 15.5 0.3 0.28 11.0 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 KFM65613.1 - 0.09 12.8 0.6 0.09 12.8 0.6 2.3 2 0 0 2 2 2 0 Winged helix-turn helix EF-hand_13 PF17958.1 KFM65614.1 - 6.2e-29 99.6 0.0 5.8e-28 96.5 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KFM65614.1 - 4.1e-20 72.0 4.0 9e-20 70.9 0.5 3.2 3 2 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM65614.1 - 1.5e-07 30.6 0.1 9.5e-05 21.7 0.0 3.8 4 0 0 4 4 4 1 EF hand EF-hand_1 PF00036.32 KFM65614.1 - 3.8e-07 29.2 0.8 0.0051 16.3 0.1 4.7 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 KFM65614.1 - 4.7e-07 29.2 1.1 0.0018 18.0 0.0 4.3 5 0 0 5 5 5 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFM65614.1 - 0.011 16.0 3.0 3.2 8.1 0.1 2.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4187 PF13821.6 KFM65614.1 - 0.015 15.0 0.3 0.048 13.4 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) EF-hand_8 PF13833.6 KFM65614.1 - 0.036 13.9 1.5 2.3 8.1 0.1 3.7 4 0 0 4 4 4 0 EF-hand domain pair LRR_10 PF18805.1 KFM65614.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat DUF5641 PF18701.1 KFM65615.1 - 1.6e-23 82.7 0.1 2e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) SpmSyn_N PF17950.1 KFM65616.1 - 0.082 13.1 0.3 0.21 11.8 0.1 1.8 1 1 1 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal DUF2757 PF10955.8 KFM65616.1 - 0.12 12.7 1.8 0.21 11.9 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) zf-CCHC PF00098.23 KFM65617.1 - 5.9e-06 26.1 1.4 8.1e-06 25.7 1.4 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM65617.1 - 0.0022 17.7 0.4 0.0036 17.0 0.4 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM65617.1 - 0.045 13.5 0.6 0.065 13.0 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle HTH_Tnp_Tc3_2 PF01498.18 KFM65621.1 - 9.6e-11 41.8 0.9 1.4e-10 41.3 0.9 1.2 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM65621.1 - 0.087 13.5 7.3 0.29 11.8 2.8 2.3 1 1 1 2 2 2 0 Homeodomain-like domain CRAL_TRIO PF00650.20 KFM65622.1 - 1.6e-30 105.9 0.1 2.6e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM65622.1 - 3.7e-06 27.1 0.0 5.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MCD_N PF17408.2 KFM65624.1 - 0.59 10.3 5.0 5.6 7.2 0.6 4.7 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain E6 PF00518.17 KFM65624.1 - 7.9 7.0 7.8 3.8 8.0 0.0 3.7 3 0 0 3 3 3 0 Early Protein (E6) ELO PF01151.18 KFM65625.1 - 5.4e-62 209.6 24.7 7.2e-62 209.2 24.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family HTH_Tnp_Tc3_2 PF01498.18 KFM65626.1 - 2.4e-12 46.9 2.7 6.9e-12 45.4 2.7 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65626.1 - 9.9e-09 35.1 0.1 2.3e-07 30.6 0.1 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.23 KFM65627.1 - 9.3e-06 25.5 1.4 1.4e-05 24.9 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM65627.1 - 0.0036 17.0 0.4 0.0063 16.2 0.4 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM65627.1 - 0.086 12.6 0.7 0.14 11.9 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle Rod_C PF10493.9 KFM65628.1 - 4.8e-46 157.3 14.4 7.3e-46 156.7 14.4 1.2 1 0 0 1 1 1 1 Rough deal protein C-terminal region HRDC PF00570.23 KFM65628.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 HRDC domain Pkinase PF00069.25 KFM65634.1 - 1.4e-30 106.5 0.0 2.2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65634.1 - 3.4e-30 105.2 0.0 1.1e-29 103.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFM65634.1 - 0.0001 23.3 9.8 0.0001 23.3 9.8 2.3 2 0 0 2 2 2 1 Activin types I and II receptor domain Choline_kinase PF01633.20 KFM65634.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase UPAR_LY6_2 PF16975.5 KFM65634.1 - 0.016 15.4 6.1 0.042 14.0 6.1 1.6 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 APH PF01636.23 KFM65634.1 - 0.022 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM65634.1 - 0.024 13.4 0.0 0.049 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Toxin_TOLIP PF00087.21 KFM65634.1 - 3.5 7.9 14.8 96 3.3 14.8 2.9 1 1 0 1 1 1 0 Snake toxin and toxin-like protein HTH_23 PF13384.6 KFM65635.1 - 6.6e-05 22.6 0.2 0.00016 21.4 0.1 1.7 1 1 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 KFM65635.1 - 0.00065 19.4 0.0 0.0018 18.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM65635.1 - 0.0018 17.7 0.9 0.015 14.7 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KFM65635.1 - 0.0024 18.0 0.2 0.0055 16.8 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 KFM65635.1 - 0.015 15.6 3.2 0.027 14.8 0.6 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KFM65635.1 - 0.02 15.2 0.4 0.024 14.9 0.4 1.2 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.6 KFM65635.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 Winged helix-turn helix Ank_4 PF13637.6 KFM65637.1 - 1.3e-25 89.4 1.5 5.8e-12 45.9 0.4 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM65637.1 - 1.1e-22 79.8 0.2 3.6e-08 33.5 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM65637.1 - 1.2e-22 80.2 0.1 6.8e-17 61.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFM65637.1 - 1.1e-18 66.7 3.7 4.2e-08 33.3 0.3 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KFM65637.1 - 6.4e-18 63.0 0.1 2.1e-05 24.5 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Cullin PF00888.22 KFM65638.1 - 9.7e-229 761.1 35.7 5.9e-145 484.3 13.4 2.6 2 1 1 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.9 KFM65638.1 - 2e-18 66.2 7.1 3.3e-18 65.5 5.1 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain Stork_head PF10264.9 KFM65638.1 - 0.011 15.9 0.6 0.054 13.7 0.6 2.2 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain HTH_6 PF01418.17 KFM65638.1 - 0.077 13.0 0.3 4 7.5 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Rap1-DNA-bind PF09197.10 KFM65638.1 - 0.36 11.5 9.1 1.4 9.5 3.5 2.7 2 0 0 2 2 2 0 Rap1, DNA-binding SVWC PF15430.6 KFM65639.1 - 0.00062 20.0 0.6 0.00082 19.6 0.6 1.3 1 0 0 1 1 1 1 Single domain von Willebrand factor type C Rol_Rep_N PF18106.1 KFM65639.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain DDE_3 PF13358.6 KFM65640.1 - 7.6e-16 58.2 0.1 7.3e-15 55.0 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65640.1 - 9.7e-16 57.8 6.5 1.7e-15 57.0 6.5 1.4 1 0 0 1 1 1 1 Transposase SVWC PF15430.6 KFM65640.1 - 3.8e-08 33.5 5.3 7.9e-08 32.5 5.3 1.6 1 0 0 1 1 1 1 Single domain von Willebrand factor type C HTH_32 PF13565.6 KFM65640.1 - 0.00086 19.9 1.5 0.00086 19.9 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM65640.1 - 0.0038 17.0 0.1 0.14 12.0 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM65640.1 - 0.02 15.0 0.1 0.075 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM65640.1 - 0.041 13.9 0.4 0.041 13.9 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix Peptidase_M3 PF01432.20 KFM65641.1 - 3.5e-144 481.5 0.7 4.9e-144 481.0 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M3 Ank_4 PF13637.6 KFM65642.1 - 1.2e-22 80.0 1.8 2.5e-10 40.7 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM65642.1 - 3.9e-18 65.8 0.2 3.2e-10 40.5 0.0 2.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM65642.1 - 8.1e-18 64.3 1.2 1.1e-13 51.2 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM65642.1 - 1.8e-17 62.9 5.7 6.5e-07 29.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFM65642.1 - 2.5e-16 58.1 1.2 9.5e-06 25.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Stk19 PF10494.9 KFM65644.1 - 6.4e-13 49.0 0.0 7.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 NFRKB_winged PF14465.6 KFM65644.1 - 0.0072 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 NFRKB Winged Helix-like CSM2 PF16834.5 KFM65644.1 - 0.062 12.9 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Shu complex component Csm2, DNA-binding STT3_PglB_C PF18527.1 KFM65644.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 STT3/PglB C-terminal beta-barrel domain 7tm_1 PF00001.21 KFM65645.1 - 1.3e-07 31.3 4.7 1.6e-07 30.9 4.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) KASH PF10541.9 KFM65646.1 - 1.9e-20 72.8 1.0 4.4e-20 71.7 1.0 1.7 1 0 0 1 1 1 1 Nuclear envelope localisation domain Spectrin PF00435.21 KFM65646.1 - 6.4e-16 58.7 62.5 5.9e-12 46.0 7.9 10.3 8 2 3 11 11 11 4 Spectrin repeat TolA_bind_tri PF16331.5 KFM65646.1 - 0.087 12.9 3.5 1.1 9.4 3.5 3.0 1 0 0 1 1 1 0 TolA binding protein trimerisation ASL_C PF08328.11 KFM65646.1 - 0.78 9.9 8.3 0.34 11.0 2.2 3.8 3 1 0 3 3 3 0 Adenylosuccinate lyase C-terminal CCDC-167 PF15188.6 KFM65647.1 - 0.0014 19.0 5.9 0.14 12.5 0.0 3.7 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 167 Tsc35 PF15079.6 KFM65647.1 - 0.034 13.7 5.1 0.046 13.3 0.1 2.2 2 0 0 2 2 2 0 Testis-specific protein 35 zf-C4H2 PF10146.9 KFM65647.1 - 0.38 11.0 9.0 0.53 10.6 0.1 3.1 2 1 0 3 3 3 0 Zinc finger-containing protein H-kinase_dim PF02895.14 KFM65647.1 - 0.94 9.9 6.8 2 8.9 0.1 2.9 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain CENP-F_leu_zip PF10473.9 KFM65647.1 - 0.97 9.5 16.4 19 5.3 2.3 4.0 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Choline_kinase PF01633.20 KFM65647.1 - 2 7.9 11.2 12 5.4 6.3 3.5 2 1 0 2 2 2 0 Choline/ethanolamine kinase DUF1759 PF03564.15 KFM65649.1 - 2.1e-30 105.6 0.2 1.1e-29 103.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM65649.1 - 6.5e-08 32.5 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 KFM65649.1 - 0.00049 20.7 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease V-SNARE PF05008.15 KFM65649.1 - 0.17 12.2 1.8 0.63 10.4 1.8 2.1 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus gag-asp_proteas PF13975.6 KFM65649.1 - 0.18 12.4 0.0 0.78 10.3 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SseC PF04888.12 KFM65650.1 - 0.0075 15.9 14.8 0.012 15.2 14.8 1.4 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Tristanin_u2 PF16638.5 KFM65650.1 - 1 10.2 2.8 1.8 9.4 1.9 2.0 1 1 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Spectrin PF00435.21 KFM65651.1 - 3.6e-64 213.8 308.9 4.1e-07 30.4 7.7 32.4 28 4 5 33 33 33 25 Spectrin repeat Pilin_PilA PF14245.6 KFM65651.1 - 0.11 12.5 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Type IV pilin PilA gpW PF02831.15 KFM65651.1 - 0.2 11.6 2.8 6.1 6.8 0.0 4.2 3 0 0 3 3 3 0 gpW T3SSipB PF16535.5 KFM65651.1 - 0.23 11.9 0.0 0.23 11.9 0.0 17.1 11 7 7 18 18 18 0 Type III cell invasion protein SipB TraC_F_IV PF11130.8 KFM65651.1 - 0.25 10.9 10.5 0.75 9.4 1.9 4.7 4 0 0 4 4 4 0 F pilus assembly Type-IV secretion system for plasmid transfer RBD-FIP PF09457.10 KFM65651.1 - 1.5 8.8 6.5 5.2 7.1 0.1 5.3 5 0 0 5 5 5 0 FIP domain Mce4_CUP1 PF11887.8 KFM65651.1 - 9.2 5.6 13.4 0.72 9.3 0.2 5.9 6 2 0 6 6 6 0 Cholesterol uptake porter CUP1 of Mce4, putative Spectrin PF00435.21 KFM65652.1 - 6.1e-54 181.0 146.9 8.2e-09 35.9 3.7 15.2 14 1 0 15 15 15 13 Spectrin repeat DHR10 PF18595.1 KFM65652.1 - 0.0054 16.8 5.7 0.0054 16.8 5.7 12.3 9 1 3 14 14 14 1 Designed helical repeat protein 10 domain TruB_N PF01509.18 KFM65652.1 - 0.073 13.4 0.3 1.1 9.6 0.1 3.1 2 0 0 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) Hpt PF01627.23 KFM65652.1 - 0.16 12.2 3.8 1.9 8.8 0.2 4.9 2 1 1 3 3 3 0 Hpt domain TPK_catalytic PF04263.16 KFM65652.1 - 0.64 10.1 4.1 35 4.5 0.1 3.9 3 1 0 3 3 3 0 Thiamin pyrophosphokinase, catalytic domain PilJ PF13675.6 KFM65652.1 - 2.2 8.3 32.6 1.7 8.7 0.3 9.8 6 5 6 12 12 12 0 Type IV pili methyl-accepting chemotaxis transducer N-term BRICHOS PF04089.14 KFM65652.1 - 3.8 7.8 6.0 2.4 8.5 1.2 3.3 2 1 0 2 2 2 0 BRICHOS domain Tox-REase-5 PF15648.6 KFM65652.1 - 4.8 7.8 7.4 43 4.7 0.0 5.3 5 0 0 5 5 5 0 Restriction endonuclease fold toxin 5 Baculo_PEP_C PF04513.12 KFM65653.1 - 0.00019 21.5 4.1 0.25 11.4 0.1 3.2 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 KFM65653.1 - 0.00031 21.2 13.0 0.26 11.8 0.1 3.6 3 0 0 3 3 3 3 Spectrin repeat OmpH PF03938.14 KFM65653.1 - 0.0054 17.1 2.3 0.0054 17.1 2.3 3.2 2 1 1 3 3 3 1 Outer membrane protein (OmpH-like) FAM184 PF15665.5 KFM65653.1 - 0.023 14.5 2.2 0.023 14.5 2.2 2.7 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B FliJ PF02050.16 KFM65653.1 - 0.036 14.3 0.2 0.036 14.3 0.2 3.7 2 1 0 3 3 3 0 Flagellar FliJ protein Sigma70_ner PF04546.13 KFM65653.1 - 0.039 13.8 0.5 0.039 13.8 0.5 2.7 2 2 0 2 2 2 0 Sigma-70, non-essential region PTPA PF03095.15 KFM65653.1 - 0.06 12.8 5.5 0.45 9.9 2.3 2.7 1 1 1 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein dCache_2 PF08269.11 KFM65653.1 - 0.11 11.6 2.9 0.22 10.7 1.4 2.0 2 0 0 2 2 2 0 Cache domain DUF1722 PF08349.11 KFM65653.1 - 0.13 12.6 2.3 22 5.4 0.0 3.8 2 1 1 4 4 4 0 Protein of unknown function (DUF1722) DUF2316 PF10078.9 KFM65653.1 - 0.19 12.0 2.2 0.3 11.4 0.0 2.4 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) SlyX PF04102.12 KFM65653.1 - 0.21 12.2 8.7 5.9 7.6 0.1 4.2 4 1 0 4 4 3 0 SlyX Spc7 PF08317.11 KFM65653.1 - 0.44 9.4 21.7 0.074 11.9 1.4 3.3 1 1 0 3 3 3 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KFM65653.1 - 0.62 10.4 15.2 0.91 9.9 0.4 4.2 4 1 1 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 KFM65653.1 - 1 9.6 19.1 5.4 7.3 3.6 4.4 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain YlqD PF11068.8 KFM65653.1 - 3.2 8.1 21.6 1.9 8.9 4.4 4.1 1 1 3 4 4 4 0 YlqD protein Exonuc_VII_S PF02609.16 KFM65653.1 - 4 7.6 10.2 0.23 11.5 0.4 3.3 3 0 0 3 3 2 0 Exonuclease VII small subunit Exonuc_VII_L PF02601.15 KFM65653.1 - 5.2 6.5 11.3 8.9e+02 -0.8 11.3 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit E6 PF00518.17 KFM65653.1 - 8.9 6.8 13.7 0.34 11.4 0.4 3.2 2 1 2 4 4 3 0 Early Protein (E6) Laminin_II PF06009.12 KFM65653.1 - 9.5 6.2 14.1 21 5.1 0.1 4.0 3 2 0 3 3 3 0 Laminin Domain II Laminin_I PF06008.14 KFM65654.1 - 0.001 18.8 0.7 0.0013 18.5 0.7 1.1 1 0 0 1 1 1 1 Laminin Domain I Prominin PF05478.11 KFM65654.1 - 0.0029 15.7 0.2 0.0029 15.6 0.2 1.0 1 0 0 1 1 1 1 Prominin FliJ PF02050.16 KFM65654.1 - 0.009 16.2 0.2 0.01 16.0 0.2 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein DASH_Spc34 PF08657.10 KFM65654.1 - 0.019 14.8 1.1 0.019 14.7 1.1 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 TCTP PF00838.17 KFM65654.1 - 0.021 15.2 0.7 0.023 15.0 0.7 1.1 1 0 0 1 1 1 0 Translationally controlled tumour protein DUF4298 PF14131.6 KFM65654.1 - 0.024 14.6 0.9 0.27 11.2 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) SYCE1 PF15233.6 KFM65654.1 - 0.025 14.6 3.6 0.04 14.0 3.6 1.3 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 PilO PF04350.13 KFM65654.1 - 0.026 14.7 0.6 0.035 14.3 0.6 1.3 1 1 0 1 1 1 0 Pilus assembly protein, PilO BRE1 PF08647.11 KFM65654.1 - 0.039 14.0 3.8 0.12 12.5 3.8 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Baculo_PEP_C PF04513.12 KFM65654.1 - 0.042 13.9 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 KFM65654.1 - 0.044 14.1 0.6 0.11 12.7 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) BLOC1_2 PF10046.9 KFM65654.1 - 0.051 13.9 1.4 0.12 12.7 1.4 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin_2 PF14523.6 KFM65654.1 - 0.097 13.0 4.3 0.98 9.8 1.1 2.2 1 1 1 2 2 2 0 Syntaxin-like protein DUF1664 PF07889.12 KFM65654.1 - 0.13 12.3 0.9 0.19 11.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PHM7_cyt PF14703.6 KFM65654.1 - 0.14 12.3 3.0 1.7 8.8 0.5 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter LMBR1 PF04791.16 KFM65654.1 - 0.33 9.8 0.7 0.34 9.8 0.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FYVE_2 PF02318.16 KFM65654.1 - 0.95 9.7 3.5 6.3 7.0 0.3 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger Spectrin PF00435.21 KFM65655.1 - 1.2e-12 48.2 60.6 0.00025 21.5 6.4 7.4 6 2 2 8 8 8 5 Spectrin repeat DUF948 PF06103.11 KFM65655.1 - 0.018 15.3 36.7 0.49 10.7 0.8 8.3 5 4 1 7 7 7 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 KFM65655.1 - 0.027 14.5 0.8 0.027 14.5 0.8 8.7 2 2 4 8 8 8 0 Designed helical repeat protein 10 domain DUF885 PF05960.11 KFM65655.1 - 0.16 11.6 17.0 32 4.0 14.6 3.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) TFIID_20kDa PF03847.13 KFM65655.1 - 0.66 10.5 7.8 0.45 11.0 0.7 4.0 3 1 0 3 3 3 0 Transcription initiation factor TFIID subunit A PilJ PF13675.6 KFM65655.1 - 1.4 9.0 20.6 1.1 9.4 1.5 5.9 6 1 1 7 7 7 0 Type IV pili methyl-accepting chemotaxis transducer N-term T3SSipB PF16535.5 KFM65655.1 - 2.9 8.4 32.2 1.3 9.5 2.3 5.8 3 3 2 5 5 5 0 Type III cell invasion protein SipB DUF2039 PF10217.9 KFM65655.1 - 4.3 7.7 8.1 2.6 8.5 0.9 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) DUF1484 PF07363.11 KFM65655.1 - 4.8 8.2 8.8 1.3 10.0 0.1 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF1484) DASH_Dam1 PF08653.10 KFM65655.1 - 6.2 6.7 6.3 40 4.1 0.1 4.9 5 0 0 5 5 5 0 DASH complex subunit Dam1 Spectrin PF00435.21 KFM65656.1 - 2.7e-13 50.3 14.3 6.9e-06 26.5 0.4 3.6 2 1 1 3 3 3 2 Spectrin repeat MscS_porin PF12795.7 KFM65656.1 - 0.012 15.2 6.1 0.073 12.6 1.9 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF5129 PF17173.4 KFM65656.1 - 0.043 12.9 1.9 0.26 10.4 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5129) TBCC_N PF16752.5 KFM65656.1 - 0.049 14.1 3.3 0.92 10.0 0.0 3.6 1 1 1 4 4 4 0 Tubulin-specific chaperone C N-terminal domain DUF1351 PF07083.11 KFM65656.1 - 0.088 12.6 6.9 0.26 11.0 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1351) DASH_Spc34 PF08657.10 KFM65656.1 - 0.29 10.9 7.5 0.089 12.6 1.3 2.5 1 1 2 3 3 3 0 DASH complex subunit Spc34 FRB_dom PF08771.11 KFM65656.1 - 0.81 10.1 5.9 16 5.9 0.4 3.1 3 1 1 4 4 4 0 FKBP12-rapamycin binding domain FliD_C PF07195.12 KFM65656.1 - 0.88 8.9 5.7 4.9 6.5 0.1 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Filament PF00038.21 KFM65656.1 - 1.1 8.7 10.5 0.29 10.7 2.2 2.2 2 0 0 2 2 2 0 Intermediate filament protein APG6_N PF17675.1 KFM65656.1 - 2.5 8.6 9.9 0.42 11.1 1.0 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region YlqD PF11068.8 KFM65656.1 - 3.1 8.2 7.9 0.86 10.0 0.4 2.5 2 1 0 2 2 2 0 YlqD protein OmpH PF03938.14 KFM65656.1 - 3.3 8.1 8.5 4.4 7.6 0.3 2.9 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) Enkurin PF13864.6 KFM65656.1 - 7.1 7.1 12.3 4.4 7.8 3.7 3.5 2 2 2 4 4 4 0 Calmodulin-binding bZIP_1 PF00170.21 KFM65656.1 - 8.4 6.6 7.8 6.7 6.9 0.2 3.3 2 1 0 2 2 2 0 bZIP transcription factor CH PF00307.31 KFM65657.1 - 3.1e-11 43.4 0.0 1.5e-10 41.2 0.0 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Peptidase_C11 PF03415.14 KFM65657.1 - 0.019 14.4 3.0 0.042 13.3 1.4 2.2 1 1 1 2 2 2 0 Clostripain family ATC_hydrolase PF14196.6 KFM65657.1 - 0.061 14.1 0.2 0.13 13.0 0.2 1.5 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase CotJB PF12652.7 KFM65657.1 - 1.9 8.7 5.8 13 6.0 0.0 4.3 6 0 0 6 6 6 0 CotJB protein CH PF00307.31 KFM65658.1 - 1.2e-21 76.9 0.0 1.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM65658.1 - 0.003 17.3 0.0 0.0062 16.3 0.0 1.5 1 1 0 1 1 1 1 CAMSAP CH domain Ribosomal_L11_N PF03946.14 KFM65659.1 - 7.4e-07 28.9 0.2 1.3e-06 28.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain SCAN PF02023.17 KFM65660.1 - 8.2e-06 25.5 0.9 2.5e-05 24.0 0.9 1.9 1 0 0 1 1 1 1 SCAN domain RT_RNaseH PF17917.1 KFM65660.1 - 2.2e-05 24.7 0.0 6.3e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 KFM65660.1 - 0.00043 20.2 0.3 0.00079 19.4 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle ATG11 PF10377.9 KFM65660.1 - 0.093 12.8 0.1 0.093 12.8 0.1 2.5 3 0 0 3 3 3 0 Autophagy-related protein 11 Ribosomal_L11 PF00298.19 KFM65661.1 - 1.2e-21 76.9 0.0 2.4e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF45 PF01863.17 KFM65661.1 - 0.092 12.8 0.5 0.13 12.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 HSP20 PF00011.21 KFM65662.1 - 1.2e-18 67.1 0.9 1.9e-18 66.4 0.1 1.6 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFM65662.1 - 0.002 17.6 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HTH_Tnp_Tc3_2 PF01498.18 KFM65663.1 - 7.7e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65663.1 - 2.4e-15 56.5 0.1 3.1e-14 53.0 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM65663.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM65663.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM65663.1 - 0.015 15.4 0.1 0.065 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM65663.1 - 0.027 14.5 2.6 0.035 14.1 0.4 2.4 2 0 0 2 2 2 0 Winged helix-turn helix HLH PF00010.26 KFM65664.1 - 1.3e-08 34.7 0.9 2.2e-08 33.9 0.9 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RrnaAD PF00398.20 KFM65665.1 - 2.7e-39 134.8 0.0 3.8e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KFM65665.1 - 0.0075 16.9 0.0 0.03 15.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.12 KFM65665.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DUF5588 PF17826.1 KFM65666.1 - 7.2e-23 81.0 1.3 9.8e-23 80.6 1.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5588) TPR_12 PF13424.6 KFM65666.1 - 4.1e-11 43.0 5.3 1.6e-06 28.3 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM65666.1 - 1.2e-06 28.2 7.1 0.0051 16.8 0.2 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM65666.1 - 3.1e-05 23.8 4.5 0.78 10.1 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM65666.1 - 0.0001 22.0 9.9 0.017 15.0 0.2 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM65666.1 - 0.00013 21.7 0.2 0.033 14.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM65666.1 - 0.00017 22.2 0.4 0.021 15.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM65666.1 - 0.0054 17.4 0.0 12 7.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM65666.1 - 0.018 14.9 0.3 13 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KFM65666.1 - 0.051 13.3 1.7 4 7.1 1.7 2.4 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 KFM65666.1 - 0.057 13.8 0.6 19 5.9 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM65666.1 - 0.073 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 MalT-like TPR region ANAPC3 PF12895.7 KFM65666.1 - 0.16 12.3 7.3 0.14 12.4 0.9 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DDE_3 PF13358.6 KFM65667.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.6 1 1 1 2 2 2 2 DDE superfamily endonuclease Pkinase PF00069.25 KFM65668.1 - 4.5e-27 95.1 0.0 5.9e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RabGAP-TBC PF00566.18 KFM65668.1 - 4.6e-17 62.4 0.2 1.5e-16 60.7 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase_Tyr PF07714.17 KFM65668.1 - 3.8e-14 52.6 0.0 7.5e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM65668.1 - 1.3e-06 28.0 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TRAPPC10 PF12584.8 KFM65669.1 - 2.2e-22 79.5 0.0 4.8e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KFM65669.1 - 2.8e-12 46.8 0.1 4.2e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_19 PF14559.6 KFM65669.1 - 0.0025 18.3 0.9 0.014 15.9 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM65669.1 - 0.083 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM65669.1 - 0.26 11.5 0.9 8.6 6.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ig_3 PF13927.6 KFM65670.1 - 8.6e-06 26.3 0.1 9.8e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM65670.1 - 0.00015 22.1 0.1 0.00018 21.8 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM65670.1 - 0.00036 20.6 0.0 0.00044 20.3 0.0 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFM65670.1 - 0.0023 17.9 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM65670.1 - 0.0082 16.3 0.1 0.0099 16.0 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM65670.1 - 0.027 14.6 0.1 0.033 14.4 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin V-set domain DDE_3 PF13358.6 KFM65671.1 - 5.9e-17 61.8 0.1 1.3e-15 57.5 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65671.1 - 1.3e-10 41.4 1.4 2.7e-10 40.4 1.0 1.7 2 0 0 2 2 2 1 Transposase Ig_3 PF13927.6 KFM65672.1 - 1.5e-07 31.9 0.2 1.7e-07 31.7 0.2 1.1 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM65672.1 - 3.2e-07 30.3 0.0 4.4e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFM65672.1 - 1.3e-06 28.7 0.2 1.4e-06 28.5 0.2 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM65672.1 - 6e-06 26.2 0.0 6.6e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM65672.1 - 0.00029 20.9 0.0 0.00034 20.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFM65672.1 - 0.051 13.2 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFM65672.1 - 0.066 13.0 0.5 0.1 12.4 0.5 1.5 1 1 0 1 1 1 0 Adenovirus E3 region protein CR1 Lig_chan-Glu_bd PF10613.9 KFM65673.1 - 2.8e-29 101.7 0.0 5.1e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 KFM65673.1 - 7.2e-27 94.1 0.1 1.1e-26 93.5 0.1 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 KFM65673.1 - 1e-23 83.9 0.0 2.4e-23 82.7 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 OppC_N PF12911.7 KFM65673.1 - 0.17 11.9 3.7 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C HTH_Tnp_Tc3_2 PF01498.18 KFM65676.1 - 2.7e-15 56.3 2.0 4.3e-15 55.7 2.0 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM65676.1 - 3e-05 24.6 7.8 7.4e-05 23.3 2.2 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM65676.1 - 0.00038 20.5 0.6 0.0052 16.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 KFM65676.1 - 0.011 15.8 0.5 0.7 10.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KFM65676.1 - 0.02 14.4 2.1 1.3 8.6 0.0 3.0 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KFM65676.1 - 0.042 13.8 0.9 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KFM65676.1 - 0.081 12.8 0.4 2.5 8.0 0.0 2.5 1 1 1 2 2 2 0 MarR family HTH_26 PF13443.6 KFM65676.1 - 0.081 13.4 0.3 5.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 KFM65676.1 - 0.25 11.2 4.9 0.74 9.7 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM65677.1 - 5.6e-16 58.5 3.5 6.2e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65677.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65677.1 - 3.1e-07 30.1 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65677.1 - 0.0029 17.4 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM65677.1 - 0.03 14.4 0.4 0.097 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM65677.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DUF4371 PF14291.6 KFM65678.1 - 2.5e-30 105.9 0.5 4.9e-30 104.9 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM65678.1 - 1.4e-09 37.6 0.2 5.2e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM65678.1 - 0.032 13.2 7.6 0.047 12.7 0.4 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MAT1 PF06391.13 KFM65678.1 - 2 8.2 7.7 2.2 8.0 2.0 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Exonuc_VII_L PF02601.15 KFM65678.1 - 8.2 5.9 8.9 5.9 6.4 1.2 2.7 3 0 0 3 3 3 0 Exonuclease VII, large subunit PSI PF01437.25 KFM65680.1 - 2.3e-09 37.6 64.7 2.3e-05 24.9 7.4 7.4 5 1 1 6 6 6 5 Plexin repeat Laminin_EGF PF00053.24 KFM65680.1 - 6.8e-06 26.1 42.9 0.0004 20.5 17.3 7.3 4 1 1 5 5 5 2 Laminin EGF domain Kelch_5 PF13854.6 KFM65680.1 - 6.9e-06 25.9 0.1 1.8e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.25 KFM65680.1 - 1.3e-05 24.7 0.1 4.3e-05 23.0 0.1 2.0 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 KFM65680.1 - 0.0022 17.9 0.1 0.0082 16.1 0.1 2.0 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 KFM65680.1 - 0.004 17.4 0.1 0.012 15.8 0.1 1.9 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 KFM65680.1 - 0.0047 16.9 0.7 0.016 15.2 0.1 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain PSI_integrin PF17205.3 KFM65680.1 - 0.0094 15.7 3.9 0.0094 15.7 3.9 7.4 8 1 0 8 8 8 4 Integrin plexin domain Kelch_1 PF01344.25 KFM65681.1 - 1.1e-21 76.1 19.9 3.6e-06 26.5 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFM65681.1 - 6.6e-19 67.7 13.4 4.5e-07 29.8 0.1 5.7 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM65681.1 - 3.1e-16 59.0 17.1 7.2e-07 29.3 0.1 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFM65681.1 - 5e-16 58.3 27.5 2.1e-09 37.1 0.3 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KFM65681.1 - 9.7e-15 53.9 14.2 5e-06 26.3 0.1 5.9 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KFM65681.1 - 4.6e-13 49.1 15.9 8.5e-05 22.7 0.0 5.7 5 1 0 5 5 5 2 Galactose oxidase, central domain CUB PF00431.20 KFM65681.1 - 1e-09 38.7 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 CUB domain EGF_2 PF07974.13 KFM65681.1 - 4.8e-09 36.4 56.7 0.0036 17.6 11.5 4.1 4 0 0 4 4 4 3 EGF-like domain EGF_Tenascin PF18720.1 KFM65681.1 - 1.9e-06 27.8 35.4 0.00029 20.8 7.4 4.2 3 1 0 3 3 3 3 Tenascin EGF domain hEGF PF12661.7 KFM65681.1 - 0.025 15.2 35.9 0.092 13.4 5.2 4.9 4 0 0 4 4 4 0 Human growth factor-like EGF Laminin_EGF PF00053.24 KFM65681.1 - 0.026 14.6 4.3 0.026 14.6 4.3 3.6 3 0 0 3 3 3 0 Laminin EGF domain tRNA_m1G_MT PF01746.21 KFM65682.1 - 8.4e-23 81.1 0.0 2.3e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Mab-21 PF03281.14 KFM65683.1 - 2.9e-53 181.1 1.1 4.5e-53 180.5 1.1 1.3 1 0 0 1 1 1 1 Mab-21 protein CLCA PF08434.11 KFM65684.1 - 1.4e-23 83.6 3.1 1.5e-21 76.9 3.1 2.6 1 1 0 1 1 1 1 Calcium-activated chloride channel N terminal Orthoreo_P10 PF07204.11 KFM65684.1 - 0.13 12.3 1.1 0.34 10.9 1.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 PPC PF04151.15 KFM65684.1 - 0.66 11.1 8.2 11 7.2 0.4 4.6 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain Acyltransferase PF01553.21 KFM65688.1 - 1.2e-16 60.6 0.1 1.4e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Acyltransferase SOBP PF15279.6 KFM65689.1 - 0.015 16.0 4.0 0.021 15.5 4.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CUB PF00431.20 KFM65689.1 - 0.1 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 CUB domain DUF2407_C PF13373.6 KFM65690.1 - 0.12 12.5 0.3 0.15 12.2 0.2 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain SSF PF00474.17 KFM65690.1 - 2.7 6.7 8.4 0.21 10.4 3.9 1.4 2 0 0 2 2 2 0 Sodium:solute symporter family SSF PF00474.17 KFM65691.1 - 3e-10 39.6 7.4 3.7e-10 39.2 7.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Astacin PF01400.24 KFM65692.1 - 5.1e-61 205.6 0.1 6.2e-61 205.4 0.1 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM65692.1 - 0.31 10.9 3.8 37 4.1 0.0 3.1 2 1 0 3 3 3 0 Matrixin EF-hand_1 PF00036.32 KFM65692.1 - 0.46 10.2 2.0 1 9.1 2.0 1.5 1 0 0 1 1 1 0 EF hand DUF4045 PF13254.6 KFM65694.1 - 0.02 14.6 0.5 0.023 14.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RTP801_C PF07809.11 KFM65696.1 - 6e-36 123.0 0.0 8.5e-36 122.5 0.0 1.2 1 0 0 1 1 1 1 RTP801 C-terminal region HTH_Tnp_Tc3_2 PF01498.18 KFM65698.1 - 5.7e-07 29.7 3.4 5.7e-07 29.7 3.4 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65698.1 - 1.5e-06 28.0 0.0 0.0057 16.4 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_32 PF13565.6 KFM65698.1 - 0.005 17.4 3.9 0.022 15.4 3.9 2.1 1 0 0 1 1 1 1 Homeodomain-like domain An_peroxidase PF03098.15 KFM65699.1 - 4.5e-180 599.7 0.0 5.6e-180 599.4 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase TMEM132 PF16070.5 KFM65701.1 - 2.9e-127 424.7 0.1 5.1e-127 424.0 0.1 1.4 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFM65701.1 - 6.8e-29 99.5 0.0 1.5e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM132D_N PF15705.5 KFM65701.1 - 8e-08 32.2 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term HTH_Tnp_Tc3_2 PF01498.18 KFM65702.1 - 2.5e-16 59.6 2.2 4.5e-16 58.8 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65702.1 - 9.8e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CUE PF02845.16 KFM65703.1 - 2.5e-06 27.1 0.2 8e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 CUE domain AIM3 PF17096.5 KFM65703.1 - 0.018 16.0 2.1 0.018 16.0 2.1 2.1 3 0 0 3 3 3 0 Altered inheritance of mitochondria protein 3 UAA PF08449.11 KFM65704.1 - 1.7e-10 40.6 0.5 1.7e-10 40.6 0.5 1.0 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 KFM65704.1 - 0.0027 16.7 0.2 0.0027 16.7 0.2 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like KxDL PF10241.9 KFM65705.1 - 0.031 14.6 3.7 0.04 14.2 3.6 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein Peptidase_U40 PF10464.9 KFM65705.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 Peptidase U40 Clr5 PF14420.6 KFM65705.1 - 0.82 9.9 3.7 4.1 7.7 0.1 2.9 2 1 1 3 3 3 0 Clr5 domain PH PF00169.29 KFM65707.1 - 2.1e-14 53.9 0.6 4.2e-14 52.9 0.6 1.5 1 0 0 1 1 1 1 PH domain CENP-B_N PF04218.13 KFM65707.1 - 4.7e-11 42.2 0.6 1.3e-10 40.8 0.6 1.8 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 KFM65707.1 - 7.2e-08 32.4 1.1 6.1e-06 26.2 0.0 3.4 3 1 1 4 4 4 1 Tc5 transposase DNA-binding domain PH_9 PF15410.6 KFM65707.1 - 0.0007 20.0 0.1 0.0022 18.3 0.1 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFM65707.1 - 0.0013 19.0 0.3 0.0054 17.0 0.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFM65707.1 - 0.0045 17.4 3.6 0.0062 16.9 1.6 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 KFM65707.1 - 0.042 14.1 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain HTH_23 PF13384.6 KFM65707.1 - 0.062 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Trp_repressor PF01371.19 KFM65707.1 - 0.09 12.9 0.2 0.25 11.5 0.1 1.7 2 0 0 2 2 2 0 Trp repressor protein gpW PF02831.15 KFM65707.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 gpW DEAD PF00270.29 KFM65708.1 - 4.8e-24 85.1 0.0 7.1e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM65708.1 - 0.081 12.9 0.2 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PIEZO PF15917.5 KFM65708.1 - 5 6.6 5.9 8.3 5.8 5.9 1.3 1 0 0 1 1 1 0 Piezo THAP PF05485.12 KFM65710.1 - 6.5e-07 30.2 1.2 1.1e-06 29.5 0.0 1.9 2 1 0 2 2 2 1 THAP domain Piwi PF02171.17 KFM65711.1 - 2e-100 336.0 0.0 2.8e-100 335.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KFM65711.1 - 8.8e-21 74.2 0.2 2.1e-20 72.9 0.2 1.6 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KFM65711.1 - 7.1e-20 72.0 0.0 2.1e-19 70.5 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFM65711.1 - 2.4e-18 65.5 0.0 5.5e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KFM65711.1 - 4e-15 55.9 0.0 1.2e-14 54.4 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 KFM65711.1 - 3.4e-10 40.1 0.0 1.9e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 Argonaute linker 2 domain Herpes_UL92 PF03048.14 KFM65712.1 - 0.079 12.7 1.1 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 UL92 family PmoA PF14100.6 KFM65712.1 - 0.086 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Methane oxygenase PmoA Ntox4 PF15541.6 KFM65712.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 4 Pyridoxal_deC PF00282.19 KFM65713.1 - 6.9e-12 44.8 0.0 4.9e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Sec16 PF12932.7 KFM65713.1 - 0.087 13.4 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region BBL5 PF07289.11 KFM65714.1 - 5.8e-147 489.1 0.1 6.6e-147 488.9 0.1 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Voldacs PF03517.13 KFM65714.1 - 0.00063 19.9 0.9 0.56 10.3 0.2 2.6 2 1 0 2 2 2 2 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 KFM65714.1 - 0.0027 17.8 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 KFM65714.1 - 0.0031 17.8 0.0 0.87 10.0 0.0 2.5 2 0 0 2 2 2 2 TFIIH p62 subunit, N-terminal domain GRAM PF02893.20 KFM65714.1 - 0.0042 17.0 0.6 2.4 8.1 0.1 2.5 1 1 0 2 2 2 2 GRAM domain bPH_3 PF14470.6 KFM65714.1 - 0.01 16.2 0.0 0.076 13.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial PH domain CENP-B_N PF04218.13 KFM65715.1 - 4.2e-06 26.3 0.1 5.9e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 KFM65715.1 - 1.2e-05 25.2 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM65715.1 - 0.00024 20.8 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KFM65715.1 - 0.00078 19.4 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KFM65715.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_psq PF05225.16 KFM65715.1 - 0.0032 17.2 0.1 0.0075 16.0 0.0 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_17 PF12728.7 KFM65715.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 KFM65715.1 - 0.027 14.6 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_26 PF13443.6 KFM65715.1 - 0.047 14.1 0.0 0.074 13.5 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_11 PF08279.12 KFM65715.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 HTH domain HTH_22 PF13309.6 KFM65715.1 - 0.16 12.0 1.1 1.1 9.4 0.7 2.3 2 1 0 2 2 2 0 HTH domain HTH_Tnp_ISL3 PF13542.6 KFM65715.1 - 0.21 11.0 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 SLBP_RNA_bind PF15247.6 KFM65716.1 - 7.9e-27 93.2 8.4 7.9e-27 93.2 8.4 2.0 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain CI-B14_5a PF07347.12 KFM65716.1 - 0.28 11.1 3.1 0.22 11.4 0.5 2.1 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Orthopox_A36R PF05950.11 KFM65716.1 - 5.5 7.1 6.2 3.3 7.8 1.9 2.3 2 0 0 2 2 2 0 Orthopoxvirus A36R protein A_deamin PF02137.18 KFM65717.1 - 5.1e-104 348.3 0.0 7.8e-104 347.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain z-alpha PF02295.17 KFM65717.1 - 1.8e-17 63.1 0.7 5.6e-09 35.9 0.2 2.7 2 0 0 2 2 2 2 Adenosine deaminase z-alpha domain dsrm PF00035.26 KFM65717.1 - 3.7e-13 50.0 2.5 2.3e-12 47.4 0.0 2.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif TrmB PF01978.19 KFM65717.1 - 0.00025 20.8 0.0 5.6 6.9 0.0 3.5 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 KFM65717.1 - 0.00037 21.1 5.2 0.01 16.5 0.0 4.1 3 1 1 4 4 4 1 Replication protein A C terminal HTH_IclR PF09339.10 KFM65717.1 - 0.00048 19.9 0.0 0.038 13.8 0.0 3.2 3 0 0 3 3 3 1 IclR helix-turn-helix domain DUF2250 PF10007.9 KFM65717.1 - 0.014 15.5 0.3 2 8.6 0.1 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2250) Rrf2 PF02082.20 KFM65717.1 - 0.038 14.3 0.3 30 5.1 0.0 3.6 3 0 0 3 3 3 0 Transcriptional regulator Macoilin PF09726.9 KFM65717.1 - 4.6 5.7 11.1 6.6 5.2 11.1 1.2 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 KFM65718.1 - 2.6e-71 240.1 0.0 3.7e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65718.1 - 5.3e-37 127.5 0.0 7.3e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM65718.1 - 2.9e-07 30.1 0.0 6e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM65718.1 - 0.00048 19.2 0.2 0.00062 18.8 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain HTH_Tnp_Tc3_2 PF01498.18 KFM65719.1 - 2.6e-16 59.6 2.8 4.8e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65719.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65719.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65719.1 - 0.0023 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65719.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain 2-Hacid_dh_C PF02826.19 KFM65721.1 - 9.3e-35 119.6 0.0 1.1e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFM65721.1 - 0.014 15.6 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SOAR PF16533.5 KFM65721.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 STIM1 Orai1-activating region zf-H2C2_2 PF13465.6 KFM65723.1 - 9.8e-16 57.4 13.7 2.7e-08 33.8 3.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65723.1 - 2.2e-11 43.5 8.1 1.6e-06 28.3 2.4 2.6 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65723.1 - 3.2e-11 43.1 7.1 3e-05 24.5 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65723.1 - 1.5e-10 40.8 6.8 0.00017 21.5 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger GAGA PF09237.11 KFM65723.1 - 7.7e-05 22.4 0.8 0.16 11.8 0.3 2.1 1 1 1 2 2 2 2 GAGA factor zf-C2H2_jaz PF12171.8 KFM65723.1 - 0.00016 21.8 2.1 0.45 10.9 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Prok-RING_1 PF14446.6 KFM65723.1 - 0.0013 18.7 0.4 0.79 9.7 0.0 2.2 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 C1_1 PF00130.22 KFM65723.1 - 0.0013 18.6 1.3 0.002 18.0 1.3 1.4 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 KFM65723.1 - 0.0021 17.8 2.4 0.94 9.3 0.1 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFM65723.1 - 0.0031 18.2 3.0 0.015 15.9 2.9 1.8 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 KFM65723.1 - 0.0038 17.2 6.9 0.13 12.3 3.6 2.2 2 0 0 2 2 2 1 BED zinc finger zf-C2HC_2 PF13913.6 KFM65723.1 - 0.011 15.7 2.7 0.48 10.4 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ta0938 PF11494.8 KFM65723.1 - 0.013 15.8 0.1 0.022 15.1 0.1 1.4 1 1 0 1 1 1 0 Ta0938 DUF2072 PF09845.9 KFM65723.1 - 0.028 14.7 2.0 0.046 14.0 2.0 1.5 1 1 0 1 1 1 0 Zn-ribbon containing protein DUF2256 PF10013.9 KFM65723.1 - 0.044 13.9 1.6 4.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Cript PF10235.9 KFM65723.1 - 0.053 14.1 1.4 0.15 12.6 1.4 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zf-CHCC PF10276.9 KFM65723.1 - 0.054 13.6 1.5 0.47 10.6 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger domain BolA PF01722.18 KFM65723.1 - 0.067 13.5 0.9 0.5 10.7 0.9 2.0 1 1 0 1 1 1 0 BolA-like protein zf-met PF12874.7 KFM65723.1 - 0.068 13.6 14.6 0.34 11.3 0.0 2.5 3 0 0 3 3 2 0 Zinc-finger of C2H2 type FYVE PF01363.21 KFM65723.1 - 0.086 13.0 5.7 1.5 9.0 5.6 2.1 1 1 0 1 1 1 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 KFM65723.1 - 0.09 12.9 2.2 0.64 10.2 1.8 2.0 1 1 1 2 2 2 0 Zinc ribbon domain XPA_N PF01286.18 KFM65723.1 - 0.09 12.8 1.4 2.4 8.3 0.1 2.2 2 0 0 2 2 2 0 XPA protein N-terminal Desulfoferrod_N PF06397.12 KFM65723.1 - 0.11 12.2 0.9 3.8 7.2 0.2 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-C2H2_2 PF12756.7 KFM65723.1 - 0.13 12.6 4.4 1.2 9.6 0.6 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM65723.1 - 0.15 11.9 0.1 0.15 11.9 0.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Ribosomal_L28 PF00830.19 KFM65723.1 - 0.17 12.1 2.1 2.5 8.4 0.6 2.2 2 0 0 2 2 2 0 Ribosomal L28 family zf-C2HE PF16278.5 KFM65723.1 - 0.25 11.8 3.7 11 6.6 1.3 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 KFM65723.1 - 0.45 10.2 4.3 9.4 5.9 0.1 2.6 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger VATC PF18716.1 KFM65723.1 - 3.3 7.7 6.9 7.6 6.5 0.1 2.9 2 1 1 3 3 3 0 Vms1-associating treble clef domain YbjQ_1 PF01906.17 KFM65724.1 - 0.077 13.6 0.2 0.14 12.9 0.2 1.4 1 0 0 1 1 1 0 Putative heavy-metal-binding RVT_1 PF00078.27 KFM65725.1 - 2.3e-47 161.3 0.1 3.2e-47 160.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M16 PF00675.20 KFM65726.1 - 1.8e-12 47.5 0.3 8.4e-10 38.8 0.0 2.9 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFM65726.1 - 1.1e-11 45.1 0.0 3.1e-09 37.1 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain M16C_assoc PF08367.11 KFM65726.1 - 4.5e-06 26.0 0.3 1.4e-05 24.4 0.3 1.9 1 0 0 1 1 1 1 Peptidase M16C associated FAM86 PF14904.6 KFM65726.1 - 0.053 13.6 0.2 0.76 9.9 0.1 2.8 2 1 0 2 2 2 0 Family of unknown function Ctr PF04145.15 KFM65727.1 - 7.5e-22 78.5 4.9 9.1e-22 78.3 4.9 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PulG PF11773.8 KFM65727.1 - 0.12 12.2 0.2 0.22 11.4 0.2 1.5 1 1 0 1 1 1 0 Type II secretory pathway pseudopilin DUF4133 PF13571.6 KFM65727.1 - 1.6 9.1 7.0 2.6 8.5 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Mito_carr PF00153.27 KFM65728.1 - 1.8e-66 220.1 1.2 1.3e-21 76.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 KFM65731.1 - 0.00012 21.0 0.1 0.00012 21.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM65733.1 - 7.7e-05 21.6 0.0 7.7e-05 21.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM65734.1 - 9.1e-66 222.5 0.1 1e-65 222.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4361 PF14274.6 KFM65734.1 - 0.09 13.1 0.0 0.16 12.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4361) p450 PF00067.22 KFM65735.1 - 2.3e-96 323.4 4.2 1.2e-94 317.6 4.2 2.1 1 1 0 1 1 1 1 Cytochrome P450 DUF4361 PF14274.6 KFM65735.1 - 0.038 14.3 0.2 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4361) Ham1p_like PF01725.16 KFM65736.1 - 9.2e-29 100.7 0.0 1.1e-28 100.5 0.0 1.1 1 0 0 1 1 1 1 Ham1 family PEX11 PF05648.14 KFM65738.1 - 4.7e-07 29.5 0.1 5e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 KFM65739.1 - 1.4e-09 37.8 0.0 1.4e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RRM_7 PF16367.5 KFM65740.1 - 1.5e-32 111.5 0.0 5.6e-32 109.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KFM65740.1 - 6.6e-26 90.3 6.8 6.2e-25 87.2 6.5 2.4 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain CEBP1_N PF16368.5 KFM65740.1 - 7.5e-19 68.4 0.6 9.8e-19 68.0 0.6 1.2 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein 1 N-terminus RRM_1 PF00076.22 KFM65740.1 - 4e-08 33.0 0.0 7e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_Tnp_Tc3_2 PF01498.18 KFM65741.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65741.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65741.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65741.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65741.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain PRKCSH PF07915.13 KFM65742.1 - 1.4e-14 54.8 6.2 1.4e-14 54.8 6.2 2.9 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KFM65742.1 - 5.5e-06 26.1 1.8 1.6e-05 24.7 1.8 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Lipase_GDSL_3 PF14606.6 KFM65742.1 - 0.022 14.9 0.2 0.052 13.7 0.2 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF4942 PF13708.6 KFM65742.1 - 0.11 12.5 1.8 0.23 11.4 1.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4942) Peptidase_M13 PF01431.21 KFM65743.1 - 2.3e-14 53.5 0.1 2.7e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM65744.1 - 2.5e-23 83.4 0.1 3.1e-23 83.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM65746.1 - 2.5e-09 37.3 0.0 3.3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 HSP20 PF00011.21 KFM65746.1 - 0.008 16.3 0.0 0.011 15.9 0.0 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family FpoO PF10621.9 KFM65746.1 - 0.036 14.4 0.1 0.044 14.1 0.1 1.1 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO HTH_29 PF13551.6 KFM65747.1 - 3.4e-07 30.2 0.0 4.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 KFM65747.1 - 0.00013 22.5 0.3 0.0018 18.9 0.1 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 KFM65747.1 - 0.00039 20.1 0.1 0.00073 19.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65747.1 - 0.00079 19.2 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 KFM65747.1 - 0.0018 18.3 0.8 0.046 13.8 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase MarR PF01047.22 KFM65747.1 - 0.0022 17.9 0.1 0.013 15.4 0.1 2.0 2 0 0 2 2 2 1 MarR family HTH_40 PF14493.6 KFM65747.1 - 0.0087 16.5 0.0 0.0097 16.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM65747.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_50 PF18024.1 KFM65747.1 - 0.043 13.4 0.2 0.079 12.6 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 KFM65747.1 - 0.05 13.7 0.1 0.071 13.3 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Chordopox_A30L PF06015.12 KFM65747.1 - 0.061 13.2 0.4 0.061 13.2 0.4 1.9 2 0 0 2 2 2 0 Chordopoxvirus A30L protein TMPIT PF07851.13 KFM65748.1 - 2.2 7.4 4.1 3.6 6.7 4.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein TFIIA PF03153.13 KFM65748.1 - 3.2 7.6 30.9 4.6 7.1 30.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5387 PF17361.2 KFM65749.1 - 0.029 14.1 0.1 0.035 13.8 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5387) TMEM52 PF14979.6 KFM65750.1 - 0.0035 17.3 0.3 0.005 16.8 0.3 1.3 1 0 0 1 1 1 1 Transmembrane 52 SCIMP PF15050.6 KFM65750.1 - 0.026 15.0 2.5 0.032 14.7 2.5 1.3 1 1 0 1 1 1 0 SCIMP protein Shisa PF13908.6 KFM65750.1 - 0.038 14.3 0.0 0.045 14.0 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator NS3_envE PF02723.14 KFM65750.1 - 0.06 13.4 4.0 0.091 12.8 4.0 1.2 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E DUF4972 PF16342.5 KFM65750.1 - 0.11 12.2 1.1 1.6 8.4 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) Rhabdo_glycop PF00974.18 KFM65750.1 - 0.16 10.4 0.5 0.2 10.1 0.5 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein WBP-1 PF11669.8 KFM65750.1 - 0.16 12.6 2.5 0.31 11.7 2.5 1.7 1 1 0 1 1 1 0 WW domain-binding protein 1 Herpes_UL73 PF03554.13 KFM65750.1 - 0.21 11.6 3.4 0.3 11.1 3.4 1.2 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein DUF5383 PF17355.2 KFM65750.1 - 0.29 11.5 1.0 0.56 10.6 1.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF4713 PF15831.5 KFM65750.1 - 0.95 10.0 8.6 1.4 9.4 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) TMIE PF16038.5 KFM65750.1 - 1.5 8.7 6.7 2.8 7.8 6.7 1.4 1 0 0 1 1 1 0 TMIE protein Use1 PF09753.9 KFM65750.1 - 8.9 5.9 8.3 13 5.5 1.8 2.0 2 0 0 2 2 2 0 Membrane fusion protein Use1 Cadherin PF00028.17 KFM65751.1 - 5.4e-14 52.4 0.0 8.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Cadherin domain ALMS_repeat PF18727.1 KFM65751.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Alstrom syndrome repeat Cadherin PF00028.17 KFM65752.1 - 0.016 15.7 0.0 0.19 12.2 0.0 2.3 2 1 0 2 2 2 0 Cadherin domain RMI1_C PF16099.5 KFM65753.1 - 0.071 12.9 0.0 0.076 12.9 0.0 1.3 1 1 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold RdRP PF05183.12 KFM65755.1 - 2.2e-07 30.0 0.0 2.2e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.12 KFM65756.1 - 7.4e-19 67.8 0.0 8.4e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.12 KFM65757.1 - 1.7e-37 129.4 0.0 2e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.12 KFM65758.1 - 2.5e-21 76.0 0.1 3.7e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF2420 PF10336.9 KFM65758.1 - 0.027 14.5 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) NAD_binding_1 PF00175.21 KFM65759.1 - 0.0027 18.3 0.0 0.0054 17.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4913 PF16259.5 KFM65759.1 - 0.032 14.3 0.0 0.08 13.0 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4913) FAD_binding_1 PF00667.20 KFM65760.1 - 1.2e-42 146.0 0.0 1.4e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_6 PF00970.24 KFM65760.1 - 0.015 15.7 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain DUF2685 PF10886.8 KFM65760.1 - 0.093 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) Flavodoxin_1 PF00258.25 KFM65761.1 - 3.6e-24 85.6 0.0 5.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin NO_synthase PF02898.15 KFM65761.1 - 3.5e-19 69.1 0.1 4.7e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain NO_synthase PF02898.15 KFM65762.1 - 7.7e-22 77.8 0.0 8e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain DUF4434 PF14488.6 KFM65762.1 - 0.17 11.9 0.0 0.18 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) NO_synthase PF02898.15 KFM65763.1 - 5.8e-51 173.6 0.0 6.4e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain TrfA PF07042.11 KFM65763.1 - 0.0041 16.2 0.0 0.0045 16.1 0.0 1.1 1 0 0 1 1 1 1 TrfA protein YqzH PF14164.6 KFM65765.1 - 0.0062 16.6 0.9 2.1 8.5 0.1 2.6 2 0 0 2 2 2 2 YqzH-like protein DUF2267 PF10025.9 KFM65765.1 - 0.04 14.2 2.6 0.071 13.4 1.4 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) 7kD_DNA_binding PF02294.18 KFM65765.1 - 0.043 13.9 0.0 0.96 9.5 0.0 2.3 2 0 0 2 2 2 0 7kD DNA-binding domain Med9 PF07544.13 KFM65765.1 - 0.052 13.6 0.0 0.052 13.6 0.0 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 JIP_LZII PF16471.5 KFM65765.1 - 1.1 9.5 6.9 2.4 8.4 0.4 3.6 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Siah-Interact_N PF09032.11 KFM65765.1 - 1.9 8.8 8.1 0.65 10.4 4.7 2.1 2 1 0 2 2 2 0 Siah interacting protein, N terminal zf-H2C2_2 PF13465.6 KFM65767.1 - 9.5e-44 145.9 41.3 4.6e-08 33.1 2.1 7.6 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65767.1 - 1.6e-24 84.9 59.6 1.9e-06 28.0 0.3 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65767.1 - 3.2e-21 74.2 57.7 0.00033 21.3 0.9 7.4 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM65767.1 - 5.9e-14 51.9 51.7 0.0011 19.3 0.6 7.1 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM65767.1 - 6.1e-10 38.7 29.2 0.05 13.4 0.1 6.6 6 0 0 6 6 6 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM65767.1 - 7.9e-10 38.8 34.3 0.0056 16.9 0.2 7.0 7 0 0 7 7 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM65767.1 - 2.3e-05 24.2 49.6 0.0081 16.1 0.7 8.1 8 0 0 8 8 8 4 C2H2-type zinc finger ADK_lid PF05191.14 KFM65767.1 - 0.0013 18.6 13.7 0.86 9.6 0.5 4.4 1 1 3 4 4 4 3 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM65767.1 - 0.0093 16.1 0.4 21 5.3 0.1 3.2 1 1 2 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Dof PF02701.15 KFM65767.1 - 0.056 13.6 18.5 0.59 10.3 0.1 4.3 1 1 3 4 4 4 0 Dof domain, zinc finger zf-MYST PF17772.1 KFM65767.1 - 0.065 12.8 0.0 0.065 12.8 0.0 5.1 7 0 0 7 7 7 0 MYST family zinc finger domain TAFII28 PF04719.14 KFM65767.1 - 0.075 13.1 0.1 0.23 11.6 0.0 1.8 2 0 0 2 2 1 0 hTAFII28-like protein conserved region zf-Sec23_Sec24 PF04810.15 KFM65767.1 - 0.27 11.3 0.1 0.27 11.3 0.1 6.3 5 1 1 6 6 6 0 Sec23/Sec24 zinc finger TRAF6_Z2 PF18048.1 KFM65767.1 - 0.34 11.0 34.3 0.84 9.8 0.5 6.7 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 zf-RRPl_C4 PF17026.5 KFM65767.1 - 0.59 10.2 25.8 0.17 12.0 6.4 3.5 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-CHCC PF10276.9 KFM65767.1 - 0.63 10.1 8.3 66 3.7 0.0 5.1 6 0 0 6 6 6 0 Zinc-finger domain DUF2256 PF10013.9 KFM65767.1 - 1.3 9.2 23.0 18 5.6 0.1 6.2 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 KFM65767.1 - 3.5 7.5 38.7 1.8 8.4 0.8 6.1 6 0 0 6 6 6 0 zinc-finger C2H2-type Sprouty PF05210.13 KFM65767.1 - 4.2 7.8 19.4 0.16 12.3 3.7 2.5 2 0 0 2 2 2 0 Sprouty protein (Spry) ArfGap PF01412.18 KFM65768.1 - 8.3e-34 116.2 0.7 2.8e-33 114.5 0.7 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Fe-S_biosyn PF01521.20 KFM65769.1 - 2.8e-16 59.7 0.0 3.5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SAND PF01342.21 KFM65770.1 - 1.6e-24 85.4 0.0 3.9e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 SAND domain zf-MYND PF01753.18 KFM65770.1 - 2e-10 40.6 15.8 2e-10 40.6 15.8 2.0 2 0 0 2 2 2 1 MYND finger MFS_1 PF07690.16 KFM65771.1 - 0.015 14.3 8.4 0.018 14.0 8.4 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily HTH_Crp_2 PF13545.6 KFM65771.1 - 0.028 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sugar_tr PF00083.24 KFM65771.1 - 0.22 10.3 3.1 0.29 9.9 3.1 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter DDE_3 PF13358.6 KFM65772.1 - 1e-13 51.3 0.0 2.2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65772.1 - 1.1e-12 48.0 2.1 2.1e-12 47.1 1.2 2.1 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM65772.1 - 1.8e-07 30.8 1.2 7.1e-07 28.9 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65772.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65772.1 - 0.048 14.3 7.9 0.43 11.2 2.0 2.9 1 1 1 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 KFM65772.1 - 0.32 11.2 4.0 0.12 12.5 0.6 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.6 KFM65773.1 - 3.6e-05 23.5 0.0 5.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease dCache_1 PF02743.18 KFM65775.1 - 1e-08 35.3 0.2 2.6e-08 34.0 0.2 1.7 1 1 0 1 1 1 1 Cache domain VWA_3 PF13768.6 KFM65776.1 - 0.065 13.2 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Cobalamin_bind PF01122.19 KFM65778.1 - 6.8e-16 58.1 0.0 8.2e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein Prenyltrans PF00432.21 KFM65778.1 - 8.6e-06 25.4 0.3 0.086 12.6 0.0 2.8 2 1 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFM65778.1 - 0.001 18.2 0.0 0.0028 16.8 0.0 1.6 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 KFM65778.1 - 0.0012 17.9 0.4 0.24 10.4 0.3 2.1 1 1 1 2 2 2 2 A-macroglobulin TED domain DUF3383 PF11863.8 KFM65778.1 - 0.0065 15.5 0.1 0.0078 15.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3383) SQHop_cyclase_N PF13249.6 KFM65778.1 - 0.011 14.9 0.0 0.17 11.0 0.0 1.9 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain Fucokinase PF07959.12 KFM65779.1 - 2.3e-23 82.8 4.5 4.2e-23 81.9 4.5 1.3 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.13 KFM65779.1 - 4.4e-06 27.0 0.0 1.2e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KFM65779.1 - 0.0068 16.6 0.5 0.017 15.3 0.5 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain CheC PF04509.12 KFM65779.1 - 0.1 12.6 0.4 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 CheC-like family Fucokinase PF07959.12 KFM65780.1 - 2.3e-16 59.8 0.0 3.7e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 KFM65780.1 - 0.016 14.8 0.0 1.9 8.0 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyl transferase CIAPIN1 PF05093.13 KFM65781.1 - 5.9e-24 84.5 18.8 5e-18 65.5 3.5 2.7 2 1 1 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF952 PF06108.12 KFM65781.1 - 0.023 14.7 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF952) DDE_1 PF03184.19 KFM65783.1 - 9.2e-30 103.6 0.3 1.4e-29 103.0 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM65783.1 - 3.2e-11 43.1 0.2 3.2e-11 43.1 0.2 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM65783.1 - 0.0065 16.2 0.0 0.073 12.8 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease LolA PF03548.15 KFM65783.1 - 0.054 13.2 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA HTH_Tnp_Tc3_2 PF01498.18 KFM65784.1 - 2.1e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65784.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease LRR_8 PF13855.6 KFM65785.1 - 3.7e-17 61.8 12.3 1.4e-07 31.2 0.6 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_5 PF13306.6 KFM65785.1 - 4.7e-08 33.1 0.1 0.00012 22.0 0.0 2.2 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM65785.1 - 1.9e-07 31.2 9.9 0.00025 21.3 0.5 4.1 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM65785.1 - 0.00086 18.9 5.7 0.57 9.7 0.7 3.1 1 1 2 3 3 3 2 Leucine-rich repeat DUF3557 PF12078.8 KFM65785.1 - 0.0061 16.5 0.5 1.8 8.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3557) LRR_6 PF13516.6 KFM65785.1 - 0.066 13.3 7.7 9.4 6.6 0.4 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KFM65785.1 - 0.55 11.0 6.1 44 5.2 0.2 4.5 4 1 0 4 4 4 0 Leucine Rich Repeat BESS PF02944.20 KFM65786.1 - 0.00012 21.8 1.4 0.00025 20.8 1.4 1.6 1 0 0 1 1 1 1 BESS motif DUF4371 PF14291.6 KFM65787.1 - 1.1e-12 48.2 0.0 1.2e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) HORMA PF02301.18 KFM65788.1 - 6.3e-06 25.9 0.2 8.9e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 HORMA domain Retrotran_gag_2 PF14223.6 KFM65788.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type THAP PF05485.12 KFM65789.1 - 5e-17 62.6 0.6 9.5e-17 61.7 0.1 1.7 2 0 0 2 2 2 1 THAP domain CagX PF03524.15 KFM65790.1 - 0.044 13.5 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein HTH_Tnp_Tc3_2 PF01498.18 KFM65791.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65791.1 - 8.9e-14 51.5 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-LYAR PF08790.11 KFM65791.1 - 0.22 11.5 0.6 1.4 8.9 0.3 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger NHL PF01436.21 KFM65792.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 NHL repeat HTH_Tnp_Tc3_2 PF01498.18 KFM65793.1 - 2.4e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65793.1 - 1e-13 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PDEase_I PF00233.19 KFM65794.1 - 2.7e-08 33.8 0.0 2.7e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Staphylcoagulse PF04022.12 KFM65794.1 - 0.36 10.4 0.0 0.36 10.4 0.0 2.2 3 0 0 3 3 3 0 Staphylocoagulase repeat HTH_Tnp_Tc3_2 PF01498.18 KFM65796.1 - 2.1e-16 59.9 2.2 4.4e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65796.1 - 9.3e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Fam20C PF06702.12 KFM65798.1 - 0.0011 18.9 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 zf-C2H2_2 PF12756.7 KFM65799.1 - 0.039 14.3 2.3 0.33 11.3 2.3 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Las1 PF04031.13 KFM65799.1 - 0.043 13.9 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 Las1-like DEP PF00610.21 KFM65801.1 - 6.8e-15 54.9 0.2 1.3e-14 54.0 0.2 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) S36_mt PF10937.8 KFM65801.1 - 2.4 9.8 6.2 53 5.4 2.2 2.8 2 1 0 2 2 2 0 Ribosomal protein S36, mitochondrial HTH_Tnp_Tc3_2 PF01498.18 KFM65802.1 - 2e-19 69.6 3.6 5.2e-19 68.3 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65802.1 - 5.6e-15 55.4 0.0 2.8e-14 53.1 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM65802.1 - 3.3e-07 30.8 2.0 3.3e-07 30.8 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KFM65802.1 - 3.4e-07 30.2 1.0 0.00016 21.7 0.0 2.8 3 0 0 3 3 2 2 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM65802.1 - 8.9e-07 28.9 2.3 7.1e-05 22.9 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65802.1 - 1e-06 28.4 3.0 1.8e-05 24.4 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM65802.1 - 2.5e-06 27.4 0.7 3.7e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM65802.1 - 0.00011 22.1 1.0 0.0014 18.5 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM65802.1 - 0.0011 19.0 0.4 0.015 15.2 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM65802.1 - 0.023 14.4 0.2 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM65802.1 - 0.039 14.0 0.1 2 8.5 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM65802.1 - 0.08 13.1 0.1 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM65802.1 - 0.15 11.6 0.2 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM65802.1 - 0.15 12.1 0.0 28 4.9 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM65802.1 - 0.26 11.1 3.9 1.4 8.8 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM65802.1 - 0.95 8.9 3.6 6.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc3_2 PF01498.18 KFM65803.1 - 2.6e-16 59.6 2.8 5e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65803.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65803.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65803.1 - 0.0023 17.6 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65803.1 - 1.8 9.2 15.7 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Syndecan PF01034.20 KFM65804.1 - 1.7e-30 104.7 0.0 2.4e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 KFM65804.1 - 0.00022 21.4 0.0 0.0003 21.0 0.0 1.3 1 0 0 1 1 1 1 Glycophorin A MGC-24 PF05283.11 KFM65804.1 - 0.03 14.8 0.0 0.043 14.3 0.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5305 PF17231.2 KFM65804.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2207 PF09972.9 KFM65804.1 - 0.033 13.0 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Bac_thur_toxin PF01338.18 KFM65804.1 - 0.035 13.6 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis toxin Podoplanin PF05808.11 KFM65804.1 - 0.06 13.5 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Podoplanin FeoB_associated PF12669.7 KFM65804.1 - 0.11 12.9 0.7 0.19 12.1 0.7 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Guanylate_cyc PF00211.20 KFM65805.1 - 3.6e-117 388.5 0.7 1.6e-57 194.1 0.0 2.7 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFM65805.1 - 1.1e-30 107.2 1.1 1.1e-30 107.2 1.1 2.0 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region HNOBA PF07701.14 KFM65805.1 - 0.0076 15.7 0.3 0.5 9.8 0.0 2.5 2 0 0 2 2 2 1 Heme NO binding associated DUF2207 PF09972.9 KFM65805.1 - 0.03 13.1 8.6 0.51 9.0 0.0 3.4 3 1 1 4 4 4 0 Predicted membrane protein (DUF2207) DUF1053 PF06327.14 KFM65805.1 - 0.5 10.9 5.6 0.089 13.4 0.8 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1053) DDE_Tnp_4 PF13359.6 KFM65806.1 - 2.4e-14 53.3 0.0 3.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM65806.1 - 0.00028 20.6 0.0 0.00036 20.2 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Somatomedin_B PF01033.17 KFM65809.1 - 0.016 15.6 12.7 0.016 15.6 12.7 2.4 2 0 0 2 2 2 0 Somatomedin B domain DDE_3 PF13358.6 KFM65811.1 - 2.3e-10 40.4 0.0 3.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65811.1 - 2.5e-10 40.4 0.6 5.2e-10 39.4 0.6 1.5 1 0 0 1 1 1 1 Transposase PAX PF00292.18 KFM65811.1 - 0.0084 16.0 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 KFM65811.1 - 0.04 14.5 1.1 0.04 14.5 1.1 2.8 2 1 1 3 3 3 0 Homeodomain-like domain MarR_2 PF12802.7 KFM65811.1 - 0.07 13.0 0.1 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 MarR family Toxin_7 PF05980.12 KFM65812.1 - 0.0039 17.4 3.8 0.0058 16.8 3.8 1.3 1 0 0 1 1 1 1 Toxin 7 Tachystatin_B PF11478.8 KFM65812.1 - 0.057 13.4 1.2 0.12 12.3 1.2 1.6 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Toxin_30 PF08117.11 KFM65812.1 - 0.07 13.4 2.7 0.12 12.6 2.7 1.4 1 0 0 1 1 1 0 Ptu family DnaB PF00772.21 KFM65812.1 - 0.099 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Toxin_7 PF05980.12 KFM65813.1 - 0.01 16.1 3.8 0.01 16.1 3.8 1.7 2 0 0 2 2 2 0 Toxin 7 Toxin_30 PF08117.11 KFM65813.1 - 0.17 12.1 2.9 0.36 11.1 2.9 1.5 1 0 0 1 1 1 0 Ptu family Tachystatin_B PF11478.8 KFM65813.1 - 0.36 10.8 3.6 0.2 11.6 1.2 1.9 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B Toxin_7 PF05980.12 KFM65814.1 - 0.0028 17.9 4.0 0.0028 17.9 4.0 1.8 2 0 0 2 2 2 1 Toxin 7 Toxin_30 PF08117.11 KFM65814.1 - 0.038 14.2 2.8 0.076 13.3 2.8 1.4 1 0 0 1 1 1 0 Ptu family Tachystatin_B PF11478.8 KFM65814.1 - 0.044 13.7 0.8 0.044 13.7 0.8 1.8 2 1 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B Toxin_7 PF05980.12 KFM65815.1 - 0.0039 17.4 3.8 0.0058 16.8 3.8 1.3 1 0 0 1 1 1 1 Toxin 7 Tachystatin_B PF11478.8 KFM65815.1 - 0.065 13.2 1.2 0.12 12.3 1.2 1.5 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Toxin_30 PF08117.11 KFM65815.1 - 0.1 12.9 2.9 0.17 12.1 2.9 1.4 1 0 0 1 1 1 0 Ptu family DUF2785 PF10978.8 KFM65815.1 - 0.19 11.5 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) RLI PF04068.15 KFM65817.1 - 0.0098 15.7 1.3 0.036 13.9 1.3 2.0 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Somatomedin_B PF01033.17 KFM65817.1 - 0.65 10.4 13.5 4.5 7.7 13.5 2.5 1 0 0 1 1 1 0 Somatomedin B domain P5CR_dimer PF14748.6 KFM65818.1 - 3.1e-40 136.6 0.7 3.1e-40 136.6 0.7 1.5 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFM65818.1 - 4.4e-18 65.7 0.0 7.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KFM65818.1 - 0.00054 20.0 0.8 0.0013 18.7 0.1 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.9 KFM65818.1 - 0.009 15.9 0.1 0.025 14.4 0.1 1.8 1 1 0 1 1 1 1 Rossmann-like domain NAD_binding_2 PF03446.15 KFM65818.1 - 0.016 15.4 0.0 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KFM65818.1 - 0.086 12.9 0.3 0.21 11.6 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF108 PF01958.18 KFM65819.1 - 1.5e-17 63.7 0.0 2.7e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 KFM65819.1 - 1.1e-09 38.9 0.0 2.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 KFM65819.1 - 6.1e-05 23.1 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.15 KFM65819.1 - 0.00086 19.5 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFM65819.1 - 0.015 15.8 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Lem_TRP PF08262.11 KFM65819.1 - 0.082 12.9 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 Leucophaea maderae tachykinin-related peptide Gp_dh_N PF00044.24 KFM65819.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ApbA PF02558.16 KFM65819.1 - 0.17 11.5 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CBM_14 PF01607.24 KFM65820.1 - 8.3e-11 41.9 3.3 8.3e-11 41.9 3.3 3.1 3 0 0 3 3 3 1 Chitin binding Peritrophin-A domain Ldl_recept_a PF00057.18 KFM65820.1 - 2.3e-10 40.5 6.5 2.3e-10 40.5 6.5 3.2 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A Polysacc_deac_1 PF01522.21 KFM65820.1 - 1.1e-09 38.3 0.3 5.5e-09 36.0 0.3 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase HMG_CoA_synt_C PF08540.10 KFM65820.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal V-ATPase_H_N PF03224.14 KFM65821.1 - 1.9e-109 365.8 8.7 1.9e-109 365.8 8.7 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KFM65821.1 - 3.7e-47 159.3 2.5 1.5e-46 157.3 0.1 3.0 3 1 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 KFM65821.1 - 4.5e-06 26.5 1.8 0.016 15.2 0.0 4.3 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 KFM65821.1 - 2.8e-05 23.7 0.1 0.00068 19.2 0.0 2.7 2 1 1 3 3 3 1 Armadillo-like HEAT_2 PF13646.6 KFM65821.1 - 0.0016 18.8 0.0 0.21 12.0 0.0 3.0 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KFM65821.1 - 0.0034 17.5 0.0 0.021 15.0 0.0 2.4 2 0 0 2 2 2 1 HEAT repeat Adaptin_N PF01602.20 KFM65821.1 - 0.0097 14.5 6.1 1.1 7.7 0.0 4.5 5 0 0 5 5 5 1 Adaptin N terminal region DUF2326 PF10088.9 KFM65821.1 - 0.039 13.7 0.2 0.29 10.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) Cnd1 PF12717.7 KFM65821.1 - 0.06 13.4 2.6 0.58 10.2 0.0 3.2 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 THAP PF05485.12 KFM65822.1 - 4.6e-18 65.9 0.6 4.6e-18 65.9 0.6 2.0 2 0 0 2 2 2 1 THAP domain GOLGA2L5 PF15070.6 KFM65822.1 - 0.00085 18.1 0.0 0.00098 17.9 0.0 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DivIC PF04977.15 KFM65822.1 - 0.036 13.8 1.9 0.063 13.1 1.9 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF848 PF05852.11 KFM65822.1 - 0.036 14.2 0.6 0.066 13.3 0.6 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) SRF-TF PF00319.18 KFM65822.1 - 0.1 12.1 3.5 0.26 10.8 3.5 1.7 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) PWWP PF00855.17 KFM65824.1 - 1.5e-16 60.6 0.2 1.5e-16 60.6 0.2 3.2 3 0 0 3 3 3 1 PWWP domain zinc_ribbon_4 PF13717.6 KFM65824.1 - 0.13 12.2 0.6 1.6 8.7 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Comm PF15957.5 KFM65826.1 - 0.00048 20.4 0.4 0.00075 19.8 0.4 1.3 1 1 0 1 1 1 1 Commissureless DUF3311 PF11755.8 KFM65826.1 - 0.15 12.0 1.3 0.27 11.2 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3311) Fer2_3 PF13085.6 KFM65829.1 - 2.7e-34 117.4 0.8 1.1e-33 115.4 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KFM65829.1 - 2.1e-09 37.8 4.5 2.1e-09 37.8 4.5 2.7 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFM65829.1 - 2e-07 31.0 3.1 2e-07 31.0 3.1 2.7 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFM65829.1 - 4.2e-07 30.3 8.6 4.2e-07 30.3 8.6 3.0 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.27 KFM65829.1 - 0.0039 17.1 9.8 0.037 14.0 1.3 3.3 3 0 0 3 3 3 2 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 KFM65829.1 - 0.0065 16.6 5.9 0.0065 16.6 5.9 3.1 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2_4 PF13510.6 KFM65829.1 - 0.095 12.8 2.7 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KFM65829.1 - 3.2 8.4 19.1 0.044 14.4 7.5 3.2 2 2 0 2 2 2 0 4Fe-4S dicluster domain WD40 PF00400.32 KFM65830.1 - 2.5e-16 59.8 0.2 0.0076 17.1 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM65830.1 - 0.032 14.5 0.0 3.4 8.0 0.0 3.2 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain COPI_C PF06957.11 KFM65830.1 - 0.87 8.3 4.2 1.4 7.6 4.2 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Cobl PF09469.10 KFM65831.1 - 3.3e-08 33.7 0.0 9.9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain RBD PF02196.15 KFM65831.1 - 2.5e-05 24.2 0.2 0.00011 22.2 0.2 2.2 1 0 0 1 1 1 1 Raf-like Ras-binding domain Rad60-SLD PF11976.8 KFM65831.1 - 0.028 14.3 0.4 0.35 10.7 0.0 2.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFM65831.1 - 0.066 13.0 0.1 0.55 10.0 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin family Ion_trans PF00520.31 KFM65832.1 - 1.3e-13 50.8 17.7 2.3e-13 50.0 17.7 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM65832.1 - 0.0023 16.7 0.4 0.0023 16.7 0.4 1.9 1 1 1 2 2 2 1 Polycystin cation channel LSDAT_euk PF18139.1 KFM65833.1 - 6.1e-20 71.7 0.0 7.6e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 KFM65833.1 - 2.5e-10 39.9 0.0 3.6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote CENP-B_dimeris PF09026.10 KFM65834.1 - 0.15 12.4 0.0 0.17 12.3 0.0 1.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain IGFBP PF00219.18 KFM65835.1 - 1.3e-08 35.3 20.6 1.3e-08 35.3 20.6 1.6 2 0 0 2 2 2 1 Insulin-like growth factor binding protein GDPD PF03009.17 KFM65840.1 - 1.5e-27 97.0 0.1 1.8e-27 96.7 0.1 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GRAM PF02893.20 KFM65841.1 - 1.6e-11 44.1 0.0 2.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KFM65841.1 - 0.0032 17.6 0.0 0.0052 16.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 LANC_like PF05147.13 KFM65842.1 - 7.5e-09 34.6 2.5 2.3e-07 29.7 0.6 1.7 1 1 1 2 2 2 2 Lanthionine synthetase C-like protein Eno-Rase_NADH_b PF12242.8 KFM65842.1 - 0.14 11.9 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1328 PF07043.13 KFM65842.1 - 6.9 7.0 8.0 5.2 7.4 3.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1328) LANC_like PF05147.13 KFM65843.1 - 3.7e-40 137.6 0.0 4.3e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Palm_thioest PF02089.15 KFM65845.1 - 7.1e-85 284.7 0.0 8.4e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 KFM65845.1 - 0.021 14.6 0.7 0.25 11.1 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Lipase_2 PF01674.18 KFM65845.1 - 0.06 12.9 0.0 0.97 8.9 0.0 2.2 2 1 0 2 2 2 0 Lipase (class 2) Peptidase_C1 PF00112.23 KFM65846.1 - 1.1e-27 97.6 0.4 1.9e-27 96.8 0.4 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM65846.1 - 1.8e-09 37.9 0.4 2.9e-09 37.2 0.4 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PAP_assoc PF03828.19 KFM65849.1 - 9.6e-13 48.1 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Cid1 family poly A polymerase PRKCSH_1 PF13015.6 KFM65854.1 - 2.8e-19 69.3 0.0 2.9e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein 5_nucleotid_C PF02872.18 KFM65856.1 - 4.6e-17 62.7 0.0 6.7e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain DUF5005 PF16396.5 KFM65856.1 - 0.068 11.8 0.0 0.085 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) SYS1 PF09801.9 KFM65857.1 - 2.4e-52 176.9 12.0 2.7e-52 176.7 12.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF3397 PF11877.8 KFM65857.1 - 0.0045 17.2 1.4 0.0045 17.2 1.4 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3397) Herpes_US9 PF06072.11 KFM65858.1 - 0.045 13.6 0.2 0.064 13.1 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 MIB_HERC2 PF06701.13 KFM65861.1 - 3.3e-50 168.2 25.6 1.8e-26 92.2 5.1 4.2 4 0 0 4 4 4 2 Mib_herc2 SH3_15 PF18346.1 KFM65861.1 - 4.1e-44 148.7 15.5 7.2e-23 80.7 0.5 3.5 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank_2 PF12796.7 KFM65861.1 - 7.5e-41 138.6 10.3 6.9e-14 52.2 0.0 4.7 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM65861.1 - 3.5e-38 129.5 8.3 4.4e-11 43.1 0.5 7.2 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM65861.1 - 5.1e-34 115.9 8.7 1.7e-11 44.1 0.1 7.2 4 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KFM65861.1 - 1e-29 101.6 19.4 0.00014 22.2 0.3 9.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 KFM65861.1 - 6e-26 87.7 8.9 0.0066 16.9 0.2 9.5 10 0 0 10 10 10 6 Ankyrin repeat zf-C3HC4_3 PF13920.6 KFM65861.1 - 8.2e-14 51.2 44.7 4.9e-08 32.7 12.0 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 KFM65861.1 - 2.1e-10 40.2 6.6 2.1e-10 40.2 6.6 3.9 5 0 0 5 5 5 1 Zinc finger, ZZ type NfeD PF01957.18 KFM65861.1 - 0.0021 18.4 0.3 3 8.3 0.0 2.9 2 0 0 2 2 2 2 NfeD-like C-terminal, partner-binding Aida_C2 PF14186.6 KFM65862.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal adhesion Dynein_heavy PF03028.15 KFM65862.1 - 0.12 12.5 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain DUF3421 PF11901.8 KFM65863.1 - 5.8e-10 39.2 0.0 1.8e-09 37.6 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3421) Pentapeptide PF00805.22 KFM65864.1 - 3.1e-42 141.7 25.6 5.3e-12 45.1 3.3 4.4 3 1 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KFM65864.1 - 5e-21 74.6 0.1 6.4e-08 32.7 0.0 3.3 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) KHA PF11834.8 KFM65864.1 - 1.3e-18 66.8 0.2 4.6e-18 65.1 0.1 2.0 2 0 0 2 2 2 1 KHA, dimerisation domain of potassium ion channel BTB_2 PF02214.22 KFM65864.1 - 2.2e-18 66.4 0.0 4.1e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.6 KFM65864.1 - 1.1e-14 54.3 0.0 7.5e-06 26.0 0.0 4.6 4 1 1 5 5 5 3 Pentapeptide repeats (9 copies) BTB PF00651.31 KFM65864.1 - 0.002 18.3 0.0 0.0074 16.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain DNA_ligase_OB PF03120.16 KFM65864.1 - 0.056 13.3 0.1 5.8 6.9 0.1 3.2 2 1 1 3 3 3 0 NAD-dependent DNA ligase OB-fold domain BTB_3 PF16017.5 KFM65864.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain zf-C2H2 PF00096.26 KFM65865.1 - 1.6e-38 129.0 80.4 1.5e-06 28.3 0.4 11.0 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65865.1 - 6.4e-32 107.5 74.9 0.00053 20.6 0.2 11.0 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM65865.1 - 2.9e-25 87.5 72.3 6.5e-07 29.5 0.8 10.9 13 0 0 13 13 12 5 Zinc-finger double domain zf-met PF12874.7 KFM65865.1 - 1.8e-24 85.3 63.7 0.0028 18.0 0.5 10.9 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM65865.1 - 1.5e-20 72.9 55.7 0.0057 16.9 1.3 10.1 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM65865.1 - 2.8e-06 27.2 70.0 0.096 12.7 0.8 10.2 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM65865.1 - 0.00011 22.5 53.5 0.073 13.4 2.2 10.3 6 4 4 10 10 10 2 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFM65865.1 - 0.00031 20.9 8.0 0.39 11.0 0.1 4.7 4 0 0 4 4 4 1 BolA-like protein zf-H2C2_5 PF13909.6 KFM65865.1 - 0.0016 18.1 32.2 0.0097 15.7 0.9 8.0 8 0 0 8 8 8 2 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KFM65865.1 - 0.0072 16.8 41.2 0.29 11.6 2.8 7.2 6 1 0 6 6 6 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KFM65865.1 - 0.091 12.5 0.0 0.091 12.5 0.0 8.3 9 0 0 9 9 8 0 zinc-finger C2H2-type Churchill PF06573.11 KFM65865.1 - 0.2 12.0 0.0 0.2 12.0 0.0 2.7 3 0 0 3 3 3 0 Churchill protein DUF3268 PF11672.8 KFM65865.1 - 0.4 11.0 18.1 0.58 10.5 0.2 4.3 4 0 0 4 4 4 0 zinc-finger-containing domain zf-Di19 PF05605.12 KFM65865.1 - 2.5 8.5 45.0 0.31 11.4 0.4 6.2 5 1 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KFM65865.1 - 4 8.1 30.3 0.76 10.5 1.5 6.2 5 1 1 6 6 6 0 Zinc finger C2H2-type, 3 repeats Rad50_zn_hook PF04423.14 KFM65865.1 - 8 6.4 10.5 26 4.8 0.1 5.0 4 1 1 5 5 5 0 Rad50 zinc hook motif Papilloma_E5 PF03025.14 KFM65866.1 - 0.0065 16.6 3.2 0.0072 16.5 3.2 1.1 1 0 0 1 1 1 1 Papillomavirus E5 Ig_3 PF13927.6 KFM65868.1 - 2.7e-13 50.3 0.4 5.9e-13 49.2 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM65868.1 - 8.2e-12 45.0 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM65868.1 - 7.6e-10 38.8 0.0 1.9e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM65868.1 - 4.6e-08 33.2 0.1 1.1e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM65868.1 - 1.3e-05 25.5 0.0 2.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM65869.1 - 1.9e-09 38.0 0.2 2.4e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM65869.1 - 2.6e-07 30.6 0.1 3.3e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM65869.1 - 4.5e-07 30.1 0.0 6.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM65869.1 - 2.1e-06 27.8 0.3 3.8e-06 27.0 0.1 1.5 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM65869.1 - 0.0013 18.9 0.1 0.0037 17.4 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM65869.1 - 0.0097 15.9 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM65870.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65870.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HMA PF00403.26 KFM65871.1 - 5.1e-69 228.6 17.3 2.4e-15 56.7 0.7 6.3 6 0 0 6 6 6 5 Heavy-metal-associated domain Hydrolase PF00702.26 KFM65871.1 - 7.9e-54 183.1 0.0 2.7e-53 181.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFM65871.1 - 1.9e-45 154.6 3.2 4.4e-45 153.4 3.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFM65871.1 - 3.7e-06 26.9 1.9 0.00011 22.0 0.5 2.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF592 PF04574.13 KFM65871.1 - 0.00042 20.1 0.0 0.0029 17.4 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF592) RRM_3 PF08777.11 KFM65871.1 - 0.0011 19.0 0.0 2.1 8.4 0.1 4.3 4 0 0 4 4 4 1 RNA binding motif Hydrolase_6 PF13344.6 KFM65871.1 - 0.0017 18.4 0.1 0.074 13.2 0.0 3.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM65871.1 - 0.019 15.4 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TM_helix PF05552.12 KFM65871.1 - 0.28 11.2 2.0 0.86 9.6 2.0 1.9 1 0 0 1 1 1 0 Conserved TM helix TctB PF07331.11 KFM65871.1 - 1.7 8.9 8.0 0.3 11.4 0.5 2.9 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Fer2_BFD PF04324.15 KFM65871.1 - 2.4 8.6 11.0 1.2e+02 3.1 0.3 5.8 5 0 0 5 5 5 0 BFD-like [2Fe-2S] binding domain ALG11_N PF15924.5 KFM65872.1 - 2.8e-89 298.7 3.7 4.2e-89 298.1 3.7 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KFM65872.1 - 3e-25 88.8 0.1 4.4e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM65872.1 - 2.3e-13 50.7 0.0 9.8e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFM65872.1 - 0.00068 19.7 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Pox_A21 PF05323.12 KFM65872.1 - 0.23 12.0 2.4 0.28 11.7 0.7 2.1 2 0 0 2 2 2 0 Poxvirus A21 Protein Med7 PF05983.11 KFM65873.1 - 4.3e-45 154.2 6.2 3.6e-44 151.2 6.2 2.0 1 1 0 1 1 1 1 MED7 protein Gp49 PF05973.14 KFM65873.1 - 0.0047 17.0 0.9 0.012 15.8 0.5 1.8 2 0 0 2 2 2 1 Phage derived protein Gp49-like (DUF891) PilO PF04350.13 KFM65873.1 - 0.023 14.8 1.2 0.037 14.2 1.2 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO DUF4504 PF14953.6 KFM65873.1 - 0.03 13.7 1.7 0.039 13.3 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) IF-2B PF01008.17 KFM65873.1 - 0.08 12.1 0.3 0.12 11.6 0.3 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family O-ag_pol_Wzy PF14296.6 KFM65874.1 - 0.18 10.4 1.1 0.21 10.2 1.1 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DDE_Tnp_1_7 PF13843.6 KFM65875.1 - 2.5e-34 119.1 0.0 3.1e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 HTH_Tnp_Tc3_2 PF01498.18 KFM65876.1 - 2.1e-16 59.9 2.2 5.3e-16 58.6 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65876.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65876.1 - 3.3e-05 23.6 1.2 0.00011 21.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain DUF3611 PF12263.8 KFM65877.1 - 0.0029 17.5 0.0 0.0039 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) SfLAP PF11139.8 KFM65877.1 - 0.0036 16.8 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein TMEM171 PF15471.6 KFM65877.1 - 0.0069 15.4 0.1 0.0096 14.9 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein family 171 DUF202 PF02656.15 KFM65877.1 - 0.0077 16.7 0.3 0.017 15.6 0.3 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF2721 PF11026.8 KFM65877.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Pox_A14 PF05767.12 KFM65877.1 - 0.092 12.9 0.4 0.14 12.3 0.4 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 YrhC PF14143.6 KFM65877.1 - 0.11 12.7 0.6 0.21 11.7 0.6 1.5 1 0 0 1 1 1 0 YrhC-like protein Neurensin PF14927.6 KFM65877.1 - 0.16 11.7 7.6 2.3 7.9 7.6 2.1 1 1 0 1 1 1 0 Neurensin DUF4083 PF13314.6 KFM65877.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF4083) DUF3040 PF11239.8 KFM65877.1 - 0.27 11.6 3.0 2.5 8.4 2.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DUF3899 PF13038.6 KFM65877.1 - 0.33 11.5 3.3 17 6.0 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) DUF4834 PF16118.5 KFM65877.1 - 0.72 10.8 0.0 0.72 10.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) PIRT PF15099.6 KFM65877.1 - 2.2 7.9 5.4 12 5.5 5.4 2.0 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3611 PF12263.8 KFM65878.1 - 0.033 14.1 0.2 0.045 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Phage_head_fibr PF11133.8 KFM65878.1 - 0.067 12.6 0.1 0.09 12.2 0.1 1.1 1 0 0 1 1 1 0 Head fiber protein DUF202 PF02656.15 KFM65878.1 - 0.069 13.6 3.2 0.23 11.9 3.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) PIRT PF15099.6 KFM65878.1 - 0.079 12.5 1.2 0.14 11.8 1.2 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family PTR2 PF00854.21 KFM65878.1 - 0.13 11.1 3.3 0.16 10.7 3.3 1.1 1 0 0 1 1 1 0 POT family Neurensin PF14927.6 KFM65878.1 - 0.13 11.9 5.3 0.26 11.0 0.1 2.1 1 1 1 2 2 2 0 Neurensin OAD_gamma PF04277.13 KFM65878.1 - 0.32 11.6 2.0 0.48 11.0 0.1 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain T-box PF00907.22 KFM65879.1 - 6.4e-14 52.6 0.1 9.1e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 T-box zf-H2C2_2 PF13465.6 KFM65880.1 - 2.5e-102 331.2 144.7 1.1e-08 35.1 1.5 18.1 18 0 0 18 18 18 17 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65880.1 - 3.8e-66 216.0 177.3 5.6e-05 23.4 3.9 17.2 17 0 0 17 17 17 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65880.1 - 8.5e-52 169.3 167.2 0.00089 19.9 1.2 17.2 17 0 0 17 17 17 17 C2H2-type zinc finger zf-met PF12874.7 KFM65880.1 - 3.2e-24 84.5 146.5 0.0013 19.0 0.5 17.5 17 0 0 17 17 17 13 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM65880.1 - 6.3e-12 45.0 107.9 0.14 12.0 8.6 17.5 17 0 0 17 17 17 7 C2H2-type zinc-finger domain GAGA PF09237.11 KFM65880.1 - 5e-11 42.2 33.4 0.078 12.8 0.4 11.3 5 4 7 12 12 12 7 GAGA factor BolA PF01722.18 KFM65880.1 - 4.8e-07 30.0 37.1 0.034 14.4 0.4 9.4 1 1 9 10 10 10 3 BolA-like protein zf-C2H2_jaz PF12171.8 KFM65880.1 - 1.4e-06 28.4 120.2 0.18 12.2 0.8 17.2 17 0 0 17 17 17 9 Zinc-finger double-stranded RNA-binding Tox-HNH-HHH PF15637.6 KFM65880.1 - 4.1e-06 26.9 10.8 0.19 11.9 0.2 5.4 3 2 3 6 6 6 3 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_11 PF16622.5 KFM65880.1 - 0.01 15.6 1.7 0.01 15.6 1.7 15.1 17 0 0 17 17 17 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM65880.1 - 0.031 14.3 140.2 0.2 11.7 2.8 17.8 17 0 0 17 17 17 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM65880.1 - 0.12 12.5 0.4 0.12 12.5 0.4 14.6 13 3 3 16 16 16 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.6 KFM65881.1 - 1.7e-19 69.3 16.9 2.8e-09 37.0 1.5 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65881.1 - 4.8e-10 39.3 19.8 1.3e-05 25.3 3.5 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65881.1 - 1.4e-06 28.6 18.5 0.00033 21.2 1.9 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM65881.1 - 0.00053 19.7 7.6 0.041 13.7 1.4 2.9 3 1 0 3 3 3 2 C2H2-type zinc-finger domain DUF2039 PF10217.9 KFM65881.1 - 0.0011 19.3 3.5 0.0012 19.1 3.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) zf-C2H2_11 PF16622.5 KFM65881.1 - 0.0026 17.5 12.4 0.02 14.6 0.4 2.9 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM65881.1 - 0.0057 16.6 19.2 0.048 13.7 2.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFM65881.1 - 0.0059 17.0 1.6 0.0059 17.0 1.6 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF2757 PF10955.8 KFM65881.1 - 0.013 15.8 4.1 0.13 12.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) zf_UBZ PF18439.1 KFM65881.1 - 0.013 15.0 3.1 0.34 10.5 0.5 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM65881.1 - 0.02 15.0 2.8 0.029 14.5 2.8 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type GAGA PF09237.11 KFM65881.1 - 0.043 13.6 2.6 2 8.3 0.1 2.7 1 1 2 3 3 3 0 GAGA factor Cript PF10235.9 KFM65881.1 - 0.048 14.2 1.7 0.048 14.2 1.7 2.0 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT OSTMP1 PF09777.9 KFM65881.1 - 0.053 12.9 3.8 2 7.7 0.5 1.9 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor FYVE PF01363.21 KFM65881.1 - 0.17 12.0 9.2 0.6 10.3 9.2 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_9 PF16293.5 KFM65881.1 - 0.2 11.5 6.0 2 8.3 0.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-FLZ PF04570.14 KFM65881.1 - 0.43 10.1 6.4 0.57 9.7 0.2 2.6 1 1 2 3 3 3 0 zinc-finger of the FCS-type, C2-C2 zf-C2H2_2 PF12756.7 KFM65881.1 - 0.91 9.9 13.6 2.3 8.6 3.4 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 KFM65881.1 - 1.1 9.4 9.6 3.6 7.7 9.6 1.8 1 1 0 1 1 1 0 Double zinc ribbon TRAF6_Z2 PF18048.1 KFM65881.1 - 1.3 9.2 9.7 14 5.8 4.1 3.0 2 1 1 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 DUF4606 PF15379.6 KFM65881.1 - 3.4 7.9 6.3 0.82 9.9 1.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) zf-DBF PF07535.12 KFM65881.1 - 3.8 7.7 10.8 3.9 7.7 0.8 2.7 2 1 0 2 2 2 0 DBF zinc finger zf-H2C2_2 PF13465.6 KFM65882.1 - 6.8e-49 162.2 54.2 1.3e-08 34.8 1.3 8.1 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65882.1 - 4.5e-29 99.3 67.9 4.2e-07 30.1 1.7 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65882.1 - 1.7e-26 90.6 64.8 1.7e-05 25.3 1.0 7.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65882.1 - 4.7e-12 45.9 43.4 0.0048 17.2 0.3 7.4 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM65882.1 - 9.1e-12 44.5 43.1 0.14 11.9 1.1 7.8 8 0 0 8 8 8 7 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM65882.1 - 1.1e-11 44.4 56.5 9.3e-05 22.3 0.5 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 KFM65882.1 - 2.5e-10 40.4 56.7 0.00038 20.7 1.2 7.4 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM65882.1 - 9.7e-07 28.4 47.6 0.12 12.1 1.2 7.0 7 0 0 7 7 7 5 zinc-finger C2H2-type Tox-HNH-HHH PF15637.6 KFM65882.1 - 2.5e-05 24.4 0.5 2.5 8.3 0.1 3.7 1 1 3 4 4 4 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif BolA PF01722.18 KFM65882.1 - 3e-05 24.2 4.5 1.5 9.2 0.0 4.7 1 1 4 5 5 5 1 BolA-like protein FYVE PF01363.21 KFM65882.1 - 6.7e-05 23.0 40.4 0.0074 16.4 11.5 4.1 1 1 3 4 4 4 3 FYVE zinc finger GAGA PF09237.11 KFM65882.1 - 0.00024 20.9 17.6 0.72 9.7 0.1 6.1 1 1 6 7 7 7 2 GAGA factor TRAF6_Z2 PF18048.1 KFM65882.1 - 0.0015 18.6 41.1 0.016 15.3 0.5 7.2 7 1 0 7 7 7 3 TNF receptor-associated factor 6 zinc finger 2 Zf_RING PF16744.5 KFM65882.1 - 0.0021 18.1 34.2 0.55 10.4 0.7 6.6 1 1 5 6 6 6 3 KIAA1045 RING finger DUF2256 PF10013.9 KFM65882.1 - 0.0022 18.0 30.6 2.6 8.3 0.6 7.1 7 0 0 7 7 7 1 Uncharacterized protein conserved in bacteria (DUF2256) C1_1 PF00130.22 KFM65882.1 - 0.0027 17.5 43.1 0.051 13.5 5.5 5.9 2 1 4 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-FPG_IleRS PF06827.14 KFM65882.1 - 0.014 15.2 12.8 6.1 6.8 0.1 5.9 6 0 0 6 6 5 0 Zinc finger found in FPG and IleRS Zn_ribbon_SprT PF17283.2 KFM65882.1 - 0.025 14.5 21.4 7.9 6.5 0.3 6.1 4 2 2 6 6 6 0 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 KFM65882.1 - 0.094 12.6 0.2 0.094 12.6 0.2 6.8 7 0 0 7 7 6 0 zinc-finger of a C2HC-type Complex1_49kDa PF00346.19 KFM65882.1 - 0.12 11.5 0.3 0.41 9.7 0.2 1.8 1 1 1 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-RRPl_C4 PF17026.5 KFM65882.1 - 0.2 11.8 32.8 1 9.5 10.5 3.8 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_2 PF12756.7 KFM65882.1 - 0.33 11.3 54.6 0.44 10.9 0.7 7.0 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) Thioredoxin_16 PF18569.1 KFM65882.1 - 0.45 10.7 12.2 7.4 6.8 0.1 3.8 1 1 3 4 4 4 0 Thioredoxin-like domain zf-C2H2_9 PF16293.5 KFM65882.1 - 0.68 9.8 33.5 4.9 7.1 0.2 6.9 2 2 5 7 7 7 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM65882.1 - 1.3 9.9 32.6 1.9 9.3 3.2 4.1 1 1 5 6 6 6 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 KFM65882.1 - 2 8.6 25.6 4.9 7.3 0.4 6.4 6 1 0 6 6 6 0 Sec23/Sec24 zinc finger C1_4 PF07975.12 KFM65882.1 - 4.6 7.5 34.8 0.44 10.8 5.2 4.5 2 1 1 4 4 4 0 TFIIH C1-like domain Viral_cys_rich PF08008.12 KFM65882.1 - 5.1 7.2 9.6 25 5.0 0.5 3.5 2 1 1 3 3 3 0 Viral cysteine rich RVT_1 PF00078.27 KFM65884.1 - 0.00011 21.8 0.1 0.00019 21.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spuma_A9PTase PF03539.14 KFM65884.1 - 0.045 13.9 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Ribosomal_L37e PF01907.19 KFM65885.1 - 6.4e-27 93.5 11.7 1.1e-26 92.7 11.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KFM65885.1 - 0.039 14.0 1.0 0.061 13.3 1.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF2688 PF10892.8 KFM65885.1 - 0.063 12.7 4.2 0.078 12.5 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) GATA PF00320.27 KFM65885.1 - 1.6 8.4 10.4 0.72 9.5 0.2 2.9 2 1 1 3 3 3 0 GATA zinc finger Isy1 PF06246.12 KFM65886.1 - 5.3e-06 26.2 0.9 5.8e-06 26.1 0.9 1.1 1 0 0 1 1 1 1 Isy1-like splicing family CENP-F_N PF10481.9 KFM65886.1 - 0.00052 19.8 0.2 0.00057 19.6 0.2 1.1 1 0 0 1 1 1 1 Cenp-F N-terminal domain Laminin_II PF06009.12 KFM65886.1 - 0.066 13.2 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II PYRIN PF02758.16 KFM65886.1 - 0.072 13.2 3.0 1.7 8.8 0.1 2.4 2 1 0 2 2 2 0 PAAD/DAPIN/Pyrin domain SCAPER_N PF16501.5 KFM65886.1 - 0.49 10.4 3.4 3 7.9 0.4 2.2 1 1 1 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum zf-CCHC PF00098.23 KFM65887.1 - 2.9e-08 33.4 8.3 0.00017 21.5 0.8 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFM65887.1 - 3e-06 26.9 13.8 2.9e-05 23.8 0.4 2.8 3 0 0 3 3 3 2 Zinc knuckle gag-asp_proteas PF13975.6 KFM65887.1 - 0.02 15.5 0.1 0.065 13.8 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease HscB_4_cys PF18256.1 KFM65887.1 - 0.029 14.2 12.4 0.28 11.0 2.8 2.6 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC_4 PF14392.6 KFM65887.1 - 0.051 13.3 4.7 1.5 8.7 0.3 3.0 3 0 0 3 3 3 0 Zinc knuckle Asp_protease_2 PF13650.6 KFM65887.1 - 0.16 12.6 0.0 0.32 11.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Mu-like_Com PF10122.9 KFM65887.1 - 0.22 11.0 4.3 0.29 10.6 0.5 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-ribbon_3 PF13248.6 KFM65887.1 - 1 8.9 5.7 0.28 10.6 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KFM65887.1 - 7.1 6.5 8.0 20 5.1 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain HTH_Tnp_Tc3_2 PF01498.18 KFM65888.1 - 1.9e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65888.1 - 7.7e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 KFM65889.1 - 1.3e-50 172.3 0.0 1.4e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65889.1 - 7e-30 104.2 0.0 7.6e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM65889.1 - 2.4e-07 30.4 0.0 3.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM65889.1 - 0.00046 19.6 0.0 0.00056 19.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM65889.1 - 0.00067 19.3 0.3 0.0008 19.0 0.3 1.1 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KFM65889.1 - 0.021 13.8 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain UBA PF00627.31 KFM65890.1 - 3e-06 27.0 0.0 5.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EssA PF10661.9 KFM65890.1 - 0.16 11.8 6.9 2.3 8.1 1.0 2.4 2 1 1 3 3 3 0 WXG100 protein secretion system (Wss), protein EssA UBA PF00627.31 KFM65891.1 - 2e-05 24.4 0.1 3.3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain STI1 PF17830.1 KFM65891.1 - 0.093 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 STI1 domain WIYLD PF10440.9 KFM65891.1 - 0.14 12.0 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Tubulin PF00091.25 KFM65893.1 - 2.1e-67 227.2 0.0 2.9e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM65893.1 - 7.3e-52 174.8 0.0 1.1e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFM65893.1 - 0.00093 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF4371 PF14291.6 KFM65894.1 - 4.4e-10 39.6 0.1 1.4e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM65894.1 - 0.0031 17.1 0.8 0.0031 17.1 0.8 2.3 2 1 0 2 2 2 1 Zinc-finger C2H2-type ABC_tran_CTD PF16326.5 KFM65895.1 - 0.043 14.1 1.0 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain gag-asp_proteas PF13975.6 KFM65895.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease FlaC_arch PF05377.11 KFM65895.1 - 8.6 6.8 7.1 0.47 10.9 0.3 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CBM_14 PF01607.24 KFM65896.1 - 2e-09 37.5 0.6 3.2e-09 36.8 0.6 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF1057 PF06342.12 KFM65897.1 - 6.8e-12 45.0 0.0 9.2e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Torsin PF06309.11 KFM65897.1 - 0.00065 19.8 0.0 0.0023 18.0 0.0 1.8 1 1 0 1 1 1 1 Torsin Pkinase PF00069.25 KFM65898.1 - 3.6e-07 29.8 0.0 3.8e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain ThiG PF05690.14 KFM65898.1 - 0.022 14.1 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Syntaxin_2 PF14523.6 KFM65901.1 - 0.051 13.9 0.3 0.084 13.2 0.3 1.4 1 1 0 1 1 1 0 Syntaxin-like protein SpoIISB_antitox PF14185.6 KFM65903.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.5 1 1 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system DUF2183 PF09949.9 KFM65904.1 - 0.064 13.6 0.0 0.087 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) CLASP_N PF12348.8 KFM65905.1 - 0.065 12.8 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 CLASP N terminal DUF247 PF03140.15 KFM65907.1 - 0.026 13.7 0.2 0.026 13.7 0.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function Bcl-2 PF00452.19 KFM65908.1 - 6.1e-14 52.5 2.2 1e-13 51.8 2.2 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Methyltransf_12 PF08242.12 KFM65909.1 - 1.7e-15 57.6 0.2 3.8e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM65909.1 - 6.3e-15 55.4 0.0 8.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM65909.1 - 1.1e-10 42.1 0.0 2.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM65909.1 - 1.4e-08 34.7 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM65909.1 - 6.8e-08 33.1 0.0 1.6e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM65909.1 - 0.00011 21.6 0.0 0.00027 20.3 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KFM65909.1 - 0.00029 20.5 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KFM65909.1 - 0.0017 17.9 0.0 0.004 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KFM65909.1 - 0.0068 16.2 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cyclin_C PF02984.19 KFM65910.1 - 1.4e-22 80.0 0.2 1.5e-22 79.9 0.2 1.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KFM65911.1 - 1.8e-27 95.6 0.3 3.3e-27 94.7 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain EF1_GNE PF00736.19 KFM65912.1 - 1e-35 121.7 2.1 1.8e-35 121.0 2.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFM65912.1 - 2.5e-10 40.6 9.2 2.5e-10 40.6 9.2 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_6 PF17171.4 KFM65912.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFM65912.1 - 0.017 15.3 0.5 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM65912.1 - 0.028 14.4 0.5 0.26 11.3 0.5 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2859 PF11072.8 KFM65912.1 - 0.045 13.5 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) MinC_N PF05209.13 KFM65912.1 - 0.045 13.7 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain DUF211 PF02680.14 KFM65912.1 - 0.1 12.8 0.3 0.28 11.4 0.3 1.8 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 GST_C PF00043.25 KFM65912.1 - 0.14 12.4 1.0 1.5 9.1 0.1 2.7 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 KFM65913.1 - 5.2e-38 128.4 8.3 1.8e-05 25.4 0.4 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM65913.1 - 2.4e-05 24.6 0.0 0.048 14.0 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM65913.1 - 0.026 13.2 0.3 1.6 7.3 0.0 3.4 3 2 1 4 4 4 0 Nucleoporin Nup120/160 Phospholip_A2_1 PF00068.19 KFM65914.1 - 2.1e-29 102.3 4.0 2.5e-29 102.0 4.0 1.1 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 KFM65914.1 - 0.018 15.3 12.5 3.7 7.8 12.5 2.4 1 1 0 1 1 1 0 Phospholipase A2 PLA2G12 PF06951.11 KFM65914.1 - 4.1 7.3 15.8 0.96 9.3 3.4 2.4 2 1 1 3 3 3 0 Group XII secretory phospholipase A2 precursor (PLA2G12) zf-C2H2 PF00096.26 KFM65915.1 - 3.7e-12 46.0 34.6 2.2e-05 24.7 0.3 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM65915.1 - 9.8e-09 35.3 1.5 9.8e-09 35.3 1.5 3.9 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM65915.1 - 3.6e-08 33.6 30.2 0.0016 19.1 0.3 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65915.1 - 3.9e-05 23.5 7.8 0.00066 19.6 0.3 3.6 3 1 0 3 3 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM65915.1 - 4.8e-05 23.6 17.6 0.074 13.5 0.1 3.3 3 0 0 3 3 3 3 Zinc-finger of C2H2 type LIM PF00412.22 KFM65915.1 - 0.00036 20.7 8.7 1.5 9.1 0.1 3.2 3 0 0 3 3 3 2 LIM domain zinc_ribbon_15 PF17032.5 KFM65915.1 - 0.00048 20.8 4.1 0.025 15.3 1.3 2.1 1 1 1 2 2 2 1 zinc-ribbon family zf-C2H2_jaz PF12171.8 KFM65915.1 - 0.0017 18.6 9.9 0.48 10.8 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding HypA PF01155.19 KFM65915.1 - 0.0026 17.7 5.6 0.15 12.1 1.0 2.2 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 KFM65915.1 - 0.0032 17.4 9.1 0.57 10.2 0.3 3.2 3 0 0 3 3 3 2 zinc-ribbon domain Cript PF10235.9 KFM65915.1 - 0.0043 17.6 2.3 0.052 14.1 0.5 2.1 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT zf_C2H2_13 PF18508.1 KFM65915.1 - 0.0076 15.8 3.3 0.13 11.9 0.2 2.8 2 0 0 2 2 2 1 Zinc finger domain zinc-ribbons_6 PF07191.12 KFM65915.1 - 0.011 15.6 7.6 0.3 11.1 2.0 2.5 1 1 1 2 2 2 0 zinc-ribbons DNA_RNApol_7kD PF03604.13 KFM65915.1 - 0.014 15.1 6.5 2.4 7.9 0.4 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.10 KFM65915.1 - 0.015 15.4 13.9 0.61 10.3 0.4 3.1 2 1 1 3 3 3 0 Zinc ribbon domain zf_UBZ PF18439.1 KFM65915.1 - 0.018 14.6 10.7 2.9 7.5 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KFM65915.1 - 0.021 14.9 6.2 0.39 10.8 6.3 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_8 PF15909.5 KFM65915.1 - 0.037 14.3 16.6 0.48 10.8 5.6 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-BED PF02892.15 KFM65915.1 - 0.045 13.8 23.6 0.079 13.0 0.7 3.2 1 1 2 3 3 3 0 BED zinc finger Desulfoferrod_N PF06397.12 KFM65915.1 - 0.097 12.3 5.4 1.3 8.7 0.1 3.1 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-ACC PF17848.1 KFM65915.1 - 0.11 12.6 6.3 3.6 7.7 0.2 3.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain CpXC PF14353.6 KFM65915.1 - 0.11 12.5 10.4 0.74 9.9 0.7 3.0 1 1 2 3 3 3 0 CpXC protein XPA_N PF01286.18 KFM65915.1 - 0.13 12.4 7.9 4.8 7.3 0.3 3.2 3 0 0 3 3 3 0 XPA protein N-terminal zf-CHY PF05495.12 KFM65915.1 - 0.14 12.7 16.6 0.06 13.8 3.5 2.3 1 1 1 2 2 2 0 CHY zinc finger Rubredoxin_2 PF18073.1 KFM65915.1 - 0.16 11.7 8.2 2.6 7.9 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-FCS PF06467.14 KFM65915.1 - 0.19 11.7 10.4 0.3 11.1 0.5 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-trcl PF13451.6 KFM65915.1 - 0.34 10.9 13.2 4 7.4 0.2 2.8 2 1 0 2 2 2 0 Probable zinc-ribbon domain PyrI_C PF02748.15 KFM65915.1 - 0.38 10.7 6.2 1.6 8.7 0.1 3.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Yippee-Mis18 PF03226.14 KFM65915.1 - 0.41 10.9 6.2 6.5 7.0 0.1 3.0 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_2 PF12756.7 KFM65915.1 - 0.44 10.9 16.2 6.4 7.2 0.4 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) YhfH PF14149.6 KFM65915.1 - 0.47 10.5 6.0 8.1 6.5 0.1 3.0 3 0 0 3 3 3 0 YhfH-like protein zf-C2HE PF16278.5 KFM65915.1 - 0.49 10.9 22.1 0.37 11.3 0.6 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_recom PF13408.6 KFM65915.1 - 0.51 10.9 14.0 1.6 9.3 0.6 3.2 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.7 KFM65915.1 - 0.57 10.2 17.6 3.6 7.6 8.4 2.5 1 1 2 3 3 3 0 Transposase zinc-ribbon domain zf-RING_7 PF02591.15 KFM65915.1 - 0.7 10.1 0.1 0.7 10.1 0.1 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain DUF2688 PF10892.8 KFM65915.1 - 0.89 9.1 9.2 1 8.8 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) DUF2256 PF10013.9 KFM65915.1 - 1 9.6 8.5 4.5 7.5 0.7 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_2 PF13240.6 KFM65915.1 - 1.9 8.3 12.5 5.4 6.9 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 KFM65915.1 - 2 8.3 25.1 1.7 8.5 0.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type TFIIS_C PF01096.18 KFM65915.1 - 3.8 7.5 10.7 21 5.1 0.3 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Spt46 PF17734.1 KFM65915.1 - 3.8 7.3 10.6 0.41 10.4 3.8 2.0 1 1 0 2 2 2 0 Spermatogenesis-associated protein 46 DUF983 PF06170.12 KFM65915.1 - 4 7.9 5.6 13 6.3 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Zn_ribbon_SprT PF17283.2 KFM65915.1 - 4 7.4 15.5 9.2 6.3 7.0 2.8 2 2 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_7 PF15269.6 KFM65915.1 - 5.8 7.1 14.6 21 5.3 0.0 3.1 1 1 2 3 3 3 0 Zinc-finger zf-C2H2 PF00096.26 KFM65916.1 - 2.2e-16 59.3 23.2 2.6e-07 30.7 1.0 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM65916.1 - 2.2e-11 43.6 19.5 2.1e-06 27.9 0.1 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM65916.1 - 6.2e-11 42.2 20.5 0.00014 22.4 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM65916.1 - 4.9e-05 23.1 14.4 0.0021 17.9 0.1 3.6 3 1 0 3 3 3 2 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM65916.1 - 0.00011 22.9 4.8 0.0006 20.5 1.2 2.0 1 1 1 2 2 2 1 zinc-ribbon family Zn_ribbon_recom PF13408.6 KFM65916.1 - 0.00082 19.8 4.8 0.11 13.1 0.1 2.8 3 0 0 3 3 3 2 Recombinase zinc beta ribbon domain zf-C2H2_jaz PF12171.8 KFM65916.1 - 0.0019 18.5 0.1 0.0019 18.5 0.1 2.9 3 0 0 3 3 2 1 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.9 KFM65916.1 - 0.0036 17.3 2.4 0.12 12.5 0.1 2.5 2 1 0 2 2 2 1 Zinc-finger domain CpXC PF14353.6 KFM65916.1 - 0.006 16.6 9.3 0.34 10.9 0.2 3.0 1 1 2 3 3 3 2 CpXC protein zf-C2H2_8 PF15909.5 KFM65916.1 - 0.01 16.1 8.8 0.33 11.3 1.4 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon DZR PF12773.7 KFM65916.1 - 0.011 15.8 6.4 0.41 10.7 6.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KFM65916.1 - 0.014 15.4 3.4 0.18 11.8 0.2 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Yippee-Mis18 PF03226.14 KFM65916.1 - 0.015 15.5 4.2 0.019 15.1 4.2 1.2 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_4 PF13717.6 KFM65916.1 - 0.021 14.8 6.1 3.4 7.7 0.0 3.2 2 1 1 3 3 3 0 zinc-ribbon domain zf-AN1 PF01428.16 KFM65916.1 - 0.021 15.0 16.3 1.2 9.4 3.0 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger zf-C2H2_11 PF16622.5 KFM65916.1 - 0.053 13.3 1.0 0.053 13.3 1.0 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type PyrI_C PF02748.15 KFM65916.1 - 0.076 12.9 6.0 6 6.9 0.1 2.8 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.6 KFM65916.1 - 0.093 12.8 17.3 0.34 11.0 0.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger HNH PF01844.23 KFM65916.1 - 0.1 12.8 15.1 0.11 12.7 0.4 3.1 3 0 0 3 3 3 0 HNH endonuclease zf-Di19 PF05605.12 KFM65916.1 - 0.21 11.9 15.6 0.45 10.9 1.4 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Evr1_Alr PF04777.13 KFM65916.1 - 0.33 11.5 9.1 3.4 8.2 0.7 3.0 1 1 1 2 2 2 0 Erv1 / Alr family zf-C2H2_2 PF12756.7 KFM65916.1 - 0.4 11.0 14.2 3.2 8.1 0.8 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CHY PF05495.12 KFM65916.1 - 0.48 10.9 12.3 4.6 7.8 12.3 2.2 1 1 0 1 1 1 0 CHY zinc finger zinc_ribbon_5 PF13719.6 KFM65916.1 - 0.94 9.3 8.4 4 7.3 3.7 2.8 1 1 1 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFM65916.1 - 1 9.5 11.4 3.1 8.0 5.0 3.0 1 1 2 3 3 3 0 Zinc ribbon domain LIM PF00412.22 KFM65916.1 - 1.2 9.5 11.8 14 6.0 3.6 3.0 2 1 0 2 2 2 0 LIM domain zf-BED PF02892.15 KFM65916.1 - 1.5 8.9 18.4 0.21 11.7 2.7 3.0 1 1 2 3 3 3 0 BED zinc finger zf-LYAR PF08790.11 KFM65916.1 - 1.5 8.8 8.8 4.3 7.3 0.3 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zinc_ribbon_12 PF11331.8 KFM65916.1 - 1.9 8.4 9.7 2 8.3 4.9 2.5 1 1 1 2 2 2 0 Probable zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFM65916.1 - 2.2 8.3 9.3 0.14 12.1 1.4 2.6 2 2 0 2 2 2 0 SprT-like zinc ribbon domain zf_ZIC PF18366.1 KFM65916.1 - 4.4 7.5 9.7 1.7 8.8 0.3 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-H2C2_2 PF13465.6 KFM65917.1 - 4.5e-08 33.2 6.4 4.5e-08 33.2 6.4 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM65917.1 - 0.00042 20.9 10.2 0.15 12.9 3.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM65917.1 - 0.00055 20.2 12.7 0.016 15.6 1.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM65917.1 - 0.00076 19.2 2.8 0.00076 19.2 2.8 2.4 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM65918.1 - 3e-07 30.5 0.4 3e-07 30.5 0.4 1.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM65918.1 - 7.3e-06 26.2 4.1 1.8e-05 25.0 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM65918.1 - 0.00027 21.5 0.2 0.00046 20.8 0.2 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM65918.1 - 0.00039 20.4 0.3 0.00069 19.5 0.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65918.1 - 0.0005 20.3 0.4 0.0007 19.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM65918.1 - 0.016 15.6 0.3 0.023 15.1 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-BED PF02892.15 KFM65918.1 - 0.017 15.2 3.7 0.021 14.9 3.7 1.2 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.12 KFM65918.1 - 0.053 13.8 0.5 0.07 13.4 0.0 1.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KFM65920.1 - 2.3e-90 293.3 83.6 4.8e-10 39.4 0.9 12.7 13 0 0 13 13 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM65920.1 - 4.2e-53 174.9 82.6 1.1e-05 25.5 0.6 12.5 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM65920.1 - 1.8e-44 146.5 78.8 0.0003 21.4 0.8 12.4 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM65920.1 - 2.9e-26 91.2 53.9 0.00016 21.8 0.1 11.5 11 0 0 11 11 11 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM65920.1 - 6.3e-21 74.1 69.8 1.4e-05 25.3 0.7 12.0 12 0 0 12 12 12 6 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM65920.1 - 3.4e-13 49.7 53.7 6.4e-05 23.2 1.5 8.1 4 2 3 8 8 8 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFM65920.1 - 2.2e-12 46.5 62.3 0.0021 17.8 0.4 12.0 12 0 0 12 12 12 5 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM65920.1 - 9.7e-12 44.4 78.5 0.0025 17.5 0.5 13.8 12 4 0 12 12 12 6 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 KFM65920.1 - 6.5e-09 36.4 39.7 0.48 11.2 0.4 7.1 1 1 8 9 9 9 7 zinc-ribbon family zf-C2HC_2 PF13913.6 KFM65920.1 - 1.6e-07 31.0 42.9 1.5 8.8 0.4 12.4 12 0 0 12 12 12 1 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM65920.1 - 4.4e-07 29.4 52.5 1.1 8.9 0.2 12.0 12 0 0 12 12 12 3 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 KFM65920.1 - 5.2e-07 30.0 74.7 0.067 13.6 0.5 12.3 2 1 10 12 12 11 3 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KFM65920.1 - 7.2e-07 29.2 50.8 0.0066 16.5 1.6 8.1 3 2 5 9 9 9 3 Zinc ribbon domain zinc_ribbon_9 PF14369.6 KFM65920.1 - 1.9e-06 28.0 34.9 0.64 10.3 0.0 11.1 11 0 0 11 11 11 1 zinc-ribbon zf-C2H2_2 PF12756.7 KFM65920.1 - 2.6e-05 24.5 61.8 0.49 10.8 0.7 10.6 1 1 9 10 10 10 4 C2H2 type zinc-finger (2 copies) HypA PF01155.19 KFM65920.1 - 4.6e-05 23.4 36.9 0.016 15.3 1.8 6.6 1 1 4 5 5 5 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PyrI_C PF02748.15 KFM65920.1 - 6.5e-05 22.8 49.6 0.5 10.3 0.3 11.6 8 2 4 12 12 12 3 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_3rep PF18868.1 KFM65920.1 - 0.00024 21.8 38.5 1.2 9.8 0.5 8.4 1 1 5 6 6 6 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 KFM65920.1 - 0.00041 20.3 0.7 0.00041 20.3 0.7 11.7 12 0 0 12 12 11 3 C2H2-type zinc finger zf-BED PF02892.15 KFM65920.1 - 0.0014 18.6 64.5 2.4 8.3 0.4 11.9 1 1 10 11 11 11 3 BED zinc finger Yop-YscD_ppl PF16693.5 KFM65920.1 - 0.0018 17.8 0.0 0.31 10.5 0.0 3.2 2 2 2 4 4 4 1 Inner membrane component of T3SS, periplasmic domain DUF2225 PF09986.9 KFM65920.1 - 0.0023 17.7 39.8 0.64 9.7 0.1 10.0 1 1 9 10 10 10 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-AN1 PF01428.16 KFM65920.1 - 0.0055 16.8 61.7 1.7 8.8 0.1 12.1 10 2 2 12 12 12 1 AN1-like Zinc finger RNase_H_2 PF13482.6 KFM65920.1 - 0.0081 16.2 0.7 4.3 7.3 0.0 3.5 1 1 3 5 5 5 1 RNase_H superfamily HNH_5 PF14279.6 KFM65920.1 - 0.011 15.6 57.1 0.24 11.3 1.3 10.9 7 4 2 9 9 9 0 HNH endonuclease LIM PF00412.22 KFM65920.1 - 0.017 15.3 8.1 0.017 15.3 8.1 8.4 3 2 4 7 7 6 0 LIM domain zf-RING_7 PF02591.15 KFM65920.1 - 0.082 13.1 29.6 2.2 8.5 0.1 8.6 9 0 0 9 9 9 0 C4-type zinc ribbon domain zf-CHCC PF10276.9 KFM65920.1 - 0.17 12.0 0.1 0.17 12.0 0.1 9.6 12 0 0 12 12 9 0 Zinc-finger domain C1_1 PF00130.22 KFM65920.1 - 0.31 11.0 58.4 3.3 7.7 2.0 10.0 1 1 10 11 11 11 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM65920.1 - 0.35 10.7 22.6 3.8 7.4 0.9 6.0 3 2 1 5 5 5 0 GAGA factor DUF3268 PF11672.8 KFM65920.1 - 0.39 11.0 33.4 1 9.7 0.6 6.3 3 2 2 7 7 7 0 zinc-finger-containing domain zf-C2H2_9 PF16293.5 KFM65920.1 - 0.81 9.6 28.1 3.1 7.7 0.0 8.4 10 1 1 11 11 10 0 C2H2 type zinc-finger (1 copy) DUF2757 PF10955.8 KFM65920.1 - 1.2 9.5 0.0 1.2 9.5 0.0 9.3 9 2 1 10 10 10 0 Protein of unknown function (DUF2757) ATPase-cat_bd PF12156.8 KFM65920.1 - 1.8 9.4 49.9 3.1 8.6 2.7 6.9 5 1 1 7 7 7 0 Putative metal-binding domain of cation transport ATPase FYDLN_acid PF09538.10 KFM65920.1 - 2.5 8.8 35.3 2.5 8.8 1.3 9.8 1 1 5 7 7 7 0 Protein of unknown function (FYDLN_acid) DUF2883 PF11097.8 KFM65920.1 - 2.8 8.1 5.7 5.8 7.1 0.1 3.8 4 1 1 5 5 3 0 Protein of unknown function (DUF2883) Zn_Tnp_IS1595 PF12760.7 KFM65920.1 - 3.7 7.6 49.5 0.075 13.0 1.8 7.0 6 2 0 6 6 6 0 Transposase zinc-ribbon domain C1_4 PF07975.12 KFM65920.1 - 4.5 7.6 44.1 3 8.2 1.0 6.7 4 2 0 6 6 6 0 TFIIH C1-like domain zf-MYST PF17772.1 KFM65920.1 - 6.5 6.4 39.2 4.1 7.1 1.0 9.2 5 3 6 11 11 11 0 MYST family zinc finger domain ADK_lid PF05191.14 KFM65920.1 - 9.2 6.3 40.6 8.9 6.4 4.5 7.7 4 3 2 6 6 6 0 Adenylate kinase, active site lid RUN PF02759.19 KFM65922.1 - 1.2e-14 54.4 0.0 2.4e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 RUN domain PLAT PF01477.23 KFM65922.1 - 1.4e-13 51.4 0.0 2.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain RUN PF02759.19 KFM65923.1 - 3.4e-07 30.3 0.3 3.4e-07 30.3 0.3 1.0 1 0 0 1 1 1 1 RUN domain dDENN PF03455.19 KFM65924.1 - 8.7e-18 64.0 0.6 8.7e-18 64.0 0.6 1.9 2 0 0 2 2 2 1 dDENN domain DENN PF02141.21 KFM65925.1 - 4.4e-52 176.7 4.5 6.2e-52 176.3 4.5 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFM65925.1 - 3.4e-14 53.4 0.2 1.2e-13 51.6 0.2 2.0 1 0 0 1 1 1 1 uDENN domain Transposase_1 PF01359.18 KFM65929.1 - 1.3e-12 47.3 1.2 2.1e-12 46.7 1.2 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM65929.1 - 0.033 14.3 0.1 0.082 13.0 0.1 1.7 1 0 0 1 1 1 0 HTH domain in Mos1 transposase DUF674 PF05056.12 KFM65930.1 - 0.073 11.9 0.2 0.062 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) ESSS PF10183.9 KFM65931.1 - 1.3e-15 57.4 0.0 2.2e-15 56.8 0.0 1.3 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) UQ_con PF00179.26 KFM65932.1 - 6.9e-38 129.5 0.0 8.9e-38 129.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Uteroglobin PF01099.17 KFM65932.1 - 0.057 13.8 0.3 0.11 12.9 0.3 1.5 1 0 0 1 1 1 0 Uteroglobin family HTH_Tnp_Tc3_2 PF01498.18 KFM65933.1 - 4.3e-16 58.9 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65933.1 - 1.2e-13 51.1 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65933.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65933.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65933.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM65934.1 - 2.3e-11 43.7 0.0 3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DRIM PF07539.12 KFM65934.1 - 0.089 11.1 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis Rcd1 PF04078.13 KFM65935.1 - 1.4e-133 444.0 2.2 1.6e-133 443.8 2.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OmdA PF13376.6 KFM65935.1 - 0.016 15.2 0.4 3 7.9 0.1 2.9 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Sas6_CC PF18594.1 KFM65935.1 - 0.14 12.0 1.3 0.32 10.8 1.3 1.6 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain NLRC4_HD2 PF17776.1 KFM65935.1 - 0.14 12.7 1.3 17 6.0 0.1 2.5 2 1 0 2 2 2 0 NLRC4 helical domain HD2 Peptidase_C12 PF01088.21 KFM65936.1 - 3.6e-67 226.2 0.0 6.7e-67 225.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFM65936.1 - 1.9e-18 66.1 0.0 4.9e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases ADH_zinc_N PF00107.26 KFM65937.1 - 1.8e-22 79.7 0.3 6.9e-22 77.8 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM65937.1 - 5.7e-16 59.8 0.0 1.2e-15 58.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM65937.1 - 1.3e-12 47.5 0.1 6e-12 45.4 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 KFM65937.1 - 0.0053 17.2 0.1 0.015 15.8 0.1 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain VirD1 PF07328.11 KFM65937.1 - 0.082 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 Skp1_POZ PF03931.15 KFM65938.1 - 2.1e-11 43.8 0.0 2.8e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain ELM2 PF01448.24 KFM65939.1 - 1e-08 35.8 0.0 2.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 KFM65939.1 - 0.00053 20.1 1.5 0.00079 19.6 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFM65939.1 - 0.0043 16.9 0.5 0.014 15.2 0.5 2.0 1 0 0 1 1 1 1 Myb DNA-binding like Sacchrp_dh_NADP PF03435.18 KFM65940.1 - 1e-18 67.9 0.1 1.4e-18 67.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KFM65940.1 - 8.7e-07 28.7 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFM65940.1 - 5.6e-06 26.4 0.0 1.2e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KFM65940.1 - 0.00084 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFM65940.1 - 0.0022 17.0 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFM65940.1 - 0.0059 16.1 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribosomal_L33 PF00471.20 KFM65940.1 - 0.12 12.8 0.1 0.31 11.5 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L33 Glyco_transf_49 PF13896.6 KFM65941.1 - 4.6e-68 230.0 0.5 5.9e-68 229.6 0.5 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan SurA_N_2 PF13623.6 KFM65941.1 - 0.12 12.3 0.7 0.18 11.6 0.7 1.4 1 0 0 1 1 1 0 SurA N-terminal domain Glyco_transf_49 PF13896.6 KFM65942.1 - 6.3e-24 84.9 0.2 6.9e-24 84.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan DDE_Tnp_IS1595 PF12762.7 KFM65943.1 - 0.032 14.2 0.0 0.033 14.2 0.0 1.1 1 0 0 1 1 1 0 ISXO2-like transposase domain zf-ACC PF17848.1 KFM65943.1 - 0.038 14.1 0.4 5.2 7.2 0.2 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DASH_Ask1 PF08655.10 KFM65943.1 - 0.057 13.3 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Ask1 Chitin_synth_1 PF01644.17 KFM65943.1 - 0.14 12.2 0.1 0.33 10.9 0.0 1.6 1 1 1 2 2 2 0 Chitin synthase Transposase_1 PF01359.18 KFM65944.1 - 2.3e-20 72.2 0.2 5.8e-20 70.9 0.2 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM65944.1 - 0.00075 19.6 0.0 0.002 18.2 0.0 1.8 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM65944.1 - 0.0011 19.6 0.1 0.0039 17.8 0.1 2.1 1 1 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 KFM65945.1 - 2.6e-07 30.5 0.0 4.6e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM65946.1 - 2.4e-10 40.4 0.0 3.2e-07 30.2 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease PPO1_DWL PF12142.8 KFM65946.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Polyphenol oxidase middle domain PLDc_3 PF13918.6 KFM65948.1 - 3.5e-39 134.3 0.4 4.5e-38 130.7 0.3 2.2 2 0 0 2 2 2 1 PLD-like domain PLDc_2 PF13091.6 KFM65948.1 - 1.9e-24 86.0 0.1 1.5e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFM65948.1 - 8.6e-14 51.1 2.4 1.4e-07 31.4 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Ricin_B_lectin PF00652.22 KFM65949.1 - 5e-13 49.4 2.1 1e-12 48.4 2.2 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain HECT PF00632.25 KFM65951.1 - 5.2e-95 318.5 0.1 7.3e-95 318.0 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFM65951.1 - 2e-49 165.3 23.8 3.7e-14 52.5 1.4 4.6 4 0 0 4 4 4 4 WW domain C2 PF00168.30 KFM65951.1 - 2.7e-15 56.5 0.2 7e-14 52.0 0.0 2.5 2 0 0 2 2 2 1 C2 domain RabGAP-TBC PF00566.18 KFM65952.1 - 0.0014 18.3 0.2 0.0047 16.6 0.2 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TLD PF07534.16 KFM65953.1 - 1.6e-27 96.4 0.2 2e-27 96.1 0.2 1.1 1 0 0 1 1 1 1 TLD Tetraspanin PF00335.20 KFM65954.1 - 2.4e-18 66.7 6.2 2.8e-18 66.5 6.2 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 KFM65954.1 - 7e-05 23.1 0.4 0.0032 17.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) OppC_N PF12911.7 KFM65954.1 - 0.045 13.7 0.1 0.045 13.7 0.1 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF4179 PF13786.6 KFM65954.1 - 0.13 12.8 0.3 0.94 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) PRT_C PF08372.10 KFM65954.1 - 0.18 11.5 0.1 0.18 11.5 0.1 1.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Rotamase_3 PF13616.6 KFM65955.1 - 3.7e-12 46.8 0.0 4e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KFM65955.1 - 2.5e-09 38.0 0.0 2.8e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Ribosomal_S5 PF00333.20 KFM65957.1 - 1.2e-26 92.5 1.7 1.5e-26 92.1 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KFM65957.1 - 1.2e-13 50.3 0.1 2.4e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KFM65958.1 - 0.015 15.9 18.0 0.019 15.5 18.0 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PRR20 PF15708.5 KFM65958.1 - 2.1 8.2 7.6 2.1 8.2 7.6 1.1 1 0 0 1 1 1 0 Proline-rich protein family 20 SRP68 PF16969.5 KFM65959.1 - 4.3e-152 508.0 16.1 4.9e-152 507.8 16.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_7 PF13176.6 KFM65959.1 - 0.0052 16.7 1.4 2.2 8.5 0.6 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM65959.1 - 0.025 14.6 6.7 0.97 9.7 3.5 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KFM65959.1 - 0.18 11.9 7.6 0.15 12.1 3.1 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KFM65959.1 - 0.21 11.5 2.8 23 5.0 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM65959.1 - 0.28 11.9 2.9 6.1 7.7 1.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SYF2 PF08231.12 KFM65960.1 - 1e-54 185.2 15.2 1e-54 185.2 15.2 2.0 1 1 1 2 2 2 1 SYF2 splicing factor Ribosomal_S30AE PF02482.19 KFM65960.1 - 0.048 14.4 0.2 0.048 14.4 0.2 2.5 3 0 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein NAD_binding_4 PF07993.12 KFM65961.1 - 6.2e-76 255.0 0.0 7.7e-76 254.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 KFM65961.1 - 2.1e-30 104.8 2.9 4.1e-30 103.8 2.9 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KFM65961.1 - 2.3e-07 30.5 0.0 8.7e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFM65961.1 - 1.3e-05 24.5 0.2 3.6e-05 23.0 0.2 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFM65961.1 - 2.7e-05 23.3 0.1 0.00034 19.7 0.2 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFM65961.1 - 0.00029 20.4 0.1 0.003 17.0 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KFM65961.1 - 0.018 15.5 0.0 0.036 14.5 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ubiquitin_4 PF18036.1 KFM65961.1 - 0.12 12.5 0.4 0.3 11.2 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain HTH_28 PF13518.6 KFM65962.1 - 2.4e-07 30.8 0.2 5.9e-07 29.5 0.0 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM65962.1 - 6.3e-07 29.4 0.5 0.00015 21.8 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM65962.1 - 2.8e-06 26.9 0.4 5e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM65962.1 - 0.00032 20.3 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 KFM65962.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KFM65962.1 - 0.0012 18.7 0.1 0.0019 18.1 0.1 1.6 1 1 1 2 2 2 1 MarR family HTH_38 PF13936.6 KFM65962.1 - 0.0016 18.2 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM65962.1 - 0.0027 17.7 0.5 0.0037 17.3 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM65962.1 - 0.0055 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Tc3 transposase HTH_32 PF13565.6 KFM65962.1 - 0.013 16.1 0.5 0.024 15.3 0.5 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_5 PF01022.20 KFM65962.1 - 0.073 12.9 0.4 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.16 KFM65962.1 - 0.078 12.5 0.1 0.078 12.5 0.1 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_Tc3_2 PF01498.18 KFM65963.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM65963.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PSS PF03034.15 KFM65964.1 - 7.5e-09 35.7 0.5 1.5e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 Phosphatidyl serine synthase HTH_Tnp_Tc3_2 PF01498.18 KFM65966.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM65966.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM65966.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM65966.1 - 0.0024 17.6 0.6 0.0069 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM65966.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Laminin_EGF PF00053.24 KFM65970.1 - 7.5e-05 22.8 29.6 0.074 13.2 17.0 3.3 2 1 1 3 3 3 2 Laminin EGF domain Ig_2 PF13895.6 KFM65970.1 - 0.00082 19.7 0.1 0.05 13.9 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFM65970.1 - 0.0013 19.3 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM65970.1 - 0.067 13.3 0.0 0.75 9.9 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin I-set domain Integrase_H2C2 PF17921.1 KFM65971.1 - 2.5e-19 69.1 0.1 3.7e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM65971.1 - 2e-05 24.7 0.0 4.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 KFM65971.1 - 0.001 19.2 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF4817 PF16087.5 KFM65972.1 - 4.6e-06 26.3 0.4 2e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) HTH_Tnp_Tc3_2 PF01498.18 KFM65972.1 - 3.2e-05 24.1 0.2 6.6e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_IclR PF09339.10 KFM65972.1 - 0.032 14.0 0.4 0.065 13.0 0.4 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Gemin6 PF06372.12 KFM65972.1 - 0.035 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Gemin6 protein DFF40 PF09230.10 KFM65972.1 - 0.035 13.7 1.5 0.068 12.8 1.2 1.4 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa MarR_2 PF12802.7 KFM65972.1 - 0.047 13.6 1.2 0.74 9.7 1.2 2.3 1 1 0 1 1 1 0 MarR family CENP-B_N PF04218.13 KFM65972.1 - 0.063 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_6 PF01418.17 KFM65972.1 - 0.083 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Angiomotin_C PF12240.8 KFM65973.1 - 7.6e-51 172.6 47.4 2.6e-48 164.4 21.2 3.0 2 0 0 2 2 2 2 Angiomotin C terminal ERM PF00769.19 KFM65973.1 - 0.0025 17.7 12.7 0.0025 17.7 12.7 3.9 2 1 2 4 4 4 1 Ezrin/radixin/moesin family zf-C2H2_12 PF18658.1 KFM65974.1 - 0.078 12.6 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger C2H2-type Ets PF00178.22 KFM65975.1 - 8.6e-36 122.3 0.8 2.1e-35 121.0 0.8 1.7 1 0 0 1 1 1 1 Ets-domain GABP-alpha PF11620.8 KFM65975.1 - 7.5e-32 109.4 2.2 1.6e-31 108.3 2.2 1.6 1 0 0 1 1 1 1 GA-binding protein alpha chain SAM_PNT PF02198.16 KFM65975.1 - 8.6e-25 86.5 0.6 2.3e-24 85.2 0.6 1.8 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain zf-rbx1 PF12678.7 KFM65976.1 - 5.4e-21 74.6 13.4 9.2e-21 73.9 13.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFM65976.1 - 5.4e-15 55.2 14.5 5.4e-15 55.2 14.5 1.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFM65976.1 - 1.8e-06 28.1 9.9 1.8e-06 28.1 9.9 2.4 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM65976.1 - 0.0041 16.9 9.8 0.0041 16.9 9.8 2.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM65976.1 - 0.16 11.9 16.0 0.52 10.2 15.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM65976.1 - 1.2 9.0 11.1 28 4.6 11.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KFM65976.1 - 6.7 6.4 22.6 4.7e+02 0.5 19.5 3.0 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type TFIID-31kDa PF02291.15 KFM65977.1 - 5.8e-45 152.3 0.1 9.4e-45 151.6 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KFM65977.1 - 4.2e-07 30.2 0.0 8.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFM65977.1 - 2.5e-05 24.3 0.0 6.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFM65977.1 - 0.00013 22.3 0.3 0.0004 20.8 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KFM65977.1 - 0.0072 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KFM65977.1 - 0.013 15.7 0.0 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TIP49_C PF17856.1 KFM65977.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 TIP49 AAA-lid domain zf-CCCH PF00642.24 KFM65978.1 - 4.5e-13 48.8 18.6 2.6e-07 30.4 2.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KFM65978.1 - 8.3e-08 32.0 0.4 7.5e-07 28.9 0.4 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KFM65978.1 - 0.00078 19.4 16.1 0.015 15.4 2.9 3.3 3 0 0 3 3 3 2 Zinc finger domain Nup35_RRM_2 PF14605.6 KFM65978.1 - 0.0015 18.4 0.4 0.022 14.8 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Torus PF16131.5 KFM65978.1 - 0.0016 19.1 10.3 0.046 14.4 0.2 3.4 4 0 0 4 4 4 2 Torus domain zf-CCCH_3 PF15663.5 KFM65978.1 - 0.24 11.6 8.5 1.8 8.8 1.4 2.5 2 1 0 2 2 2 0 Zinc-finger containing family Transformer PF06495.11 KFM65978.1 - 2.5 8.2 28.0 3.9 7.5 28.0 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein Hepatitis_core PF00906.20 KFM65978.1 - 7.9 6.0 14.4 11 5.5 14.4 1.2 1 0 0 1 1 1 0 Hepatitis core antigen Integrase_H2C2 PF17921.1 KFM65979.1 - 0.0011 19.0 0.0 0.0012 18.9 0.0 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain WD40 PF00400.32 KFM65981.1 - 5.3e-08 33.4 5.7 0.0023 18.7 0.1 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF357 PF04010.13 KFM65981.1 - 0.23 11.6 1.5 0.48 10.5 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Ig_3 PF13927.6 KFM65985.1 - 2.8e-53 178.4 0.6 8.2e-16 58.4 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 KFM65985.1 - 1.3e-46 156.5 0.0 1.4e-17 63.6 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 KFM65985.1 - 2.2e-36 123.9 0.0 1.5e-11 44.3 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFM65985.1 - 2.8e-33 114.1 0.3 6.6e-11 42.4 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFM65985.1 - 2.2e-18 66.4 2.4 0.034 14.3 0.1 6.7 4 4 3 7 7 7 5 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM65985.1 - 1.7e-09 37.1 0.0 0.18 11.4 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.12 KFM65985.1 - 6.6e-05 22.9 4.6 0.18 11.9 0.0 4.9 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM65985.1 - 0.00017 21.6 0.1 3.4 7.8 0.0 3.9 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain UL141 PF16758.5 KFM65985.1 - 0.0013 18.5 0.1 0.53 10.0 0.1 2.5 2 0 0 2 2 2 2 Herpes-like virus membrane glycoprotein UL141 C1-set PF07654.15 KFM65985.1 - 0.043 14.2 0.0 1 9.8 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin C1-set domain DUF753 PF05444.12 KFM65986.1 - 0.0081 16.1 4.7 0.0091 16.0 2.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF753) UPAR_LY6 PF00021.21 KFM65986.1 - 0.028 15.1 1.9 0.055 14.2 1.9 1.7 1 1 0 1 1 1 0 u-PAR/Ly-6 domain CPSase_L_D2 PF02786.17 KFM65987.1 - 1.3e-79 266.6 0.1 2e-79 266.0 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KFM65987.1 - 3.6e-70 235.8 0.0 5.7e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KFM65987.1 - 1.5e-42 144.6 0.0 3.8e-42 143.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFM65987.1 - 6.6e-33 113.0 0.0 1.3e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KFM65987.1 - 4.6e-25 88.7 0.0 1.2e-24 87.3 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Dala_Dala_lig_C PF07478.13 KFM65987.1 - 1.1e-09 38.1 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFM65987.1 - 6.1e-08 32.4 0.1 1.4e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFM65987.1 - 1.3e-05 25.4 0.1 2.8e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KFM65987.1 - 0.00053 19.6 0.1 0.0012 18.4 0.1 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KFM65987.1 - 0.0069 16.0 0.1 0.018 14.7 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain TTL PF03133.15 KFM65987.1 - 0.037 13.2 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KFM65987.1 - 0.11 11.7 0.1 0.54 9.5 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp BTB PF00651.31 KFM65990.1 - 8.4e-17 61.4 0.1 5.2e-10 39.6 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM65990.1 - 2.4e-08 34.0 3.4 2e-07 31.0 0.2 3.2 3 0 0 3 3 3 1 BTB And C-terminal Kelch RHD3 PF05879.12 KFM65990.1 - 0.065 11.4 0.0 0.096 10.8 0.0 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Sulfatase PF00884.23 KFM65991.1 - 2.6e-51 174.9 0.0 4.1e-50 170.9 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFM65991.1 - 5.4e-08 32.8 0.1 0.00022 20.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFM65991.1 - 1.2e-05 24.2 0.4 2.1e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KFM65991.1 - 0.00012 22.3 0.5 0.00034 20.8 0.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) DUF1501 PF07394.12 KFM65991.1 - 0.061 12.4 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) p450 PF00067.22 KFM65992.1 - 1.6e-81 274.4 0.0 1.8e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF755 PF05501.11 KFM65993.1 - 0.0019 18.5 0.2 0.0024 18.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF755) U79_P34 PF03064.16 KFM65993.1 - 0.019 14.3 0.5 0.022 14.1 0.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pkinase PF00069.25 KFM65994.1 - 1.1e-30 106.9 0.0 1.4e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM65994.1 - 1.7e-26 93.0 0.0 2e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM65994.1 - 5e-06 26.0 0.0 6.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM65994.1 - 0.001 18.0 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KFM65994.1 - 0.0072 15.4 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 FH2 PF02181.23 KFM65996.1 - 0.015 14.4 3.5 0.073 12.2 3.8 1.7 1 1 0 1 1 1 0 Formin Homology 2 Domain CTD_bind PF04818.13 KFM65996.1 - 0.046 14.5 0.1 0.92 10.4 0.1 2.5 1 1 1 2 2 2 0 RNA polymerase II-binding domain. DUF19 PF01579.18 KFM65996.1 - 0.05 13.4 20.4 0.55 10.0 20.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF19) Dak2 PF02734.17 KFM65996.1 - 0.072 13.0 0.3 0.49 10.3 0.2 2.0 1 1 1 2 2 2 0 DAK2 domain LZ3wCH PF18517.1 KFM65996.1 - 3.2 7.9 7.8 0.97 9.6 0.1 2.5 2 1 0 2 2 2 0 Leucine zipper with capping helix domain DDE_3 PF13358.6 KFM65997.1 - 1.2e-16 60.8 0.2 1.3e-15 57.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM65997.1 - 1.8e-10 40.9 2.1 3.9e-10 39.8 1.0 2.0 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM65997.1 - 4.8e-06 27.1 2.8 0.00012 22.7 0.0 3.4 3 1 0 3 3 3 1 Homeodomain-like domain gag-asp_proteas PF13975.6 KFM65998.1 - 3.1e-06 27.7 0.3 1.2e-05 25.8 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM65998.1 - 5.7e-05 23.7 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1664 PF07889.12 KFM65998.1 - 0.0021 18.1 5.0 0.0021 18.1 5.0 1.9 3 0 0 3 3 2 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 KFM65998.1 - 0.016 15.1 2.5 0.026 14.4 2.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF16 PF01519.16 KFM65998.1 - 0.036 14.6 3.6 0.13 12.8 3.6 2.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 KFM65998.1 - 0.1 12.6 0.5 0.39 10.7 0.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KFM65998.1 - 0.2 12.2 5.6 0.58 10.7 2.4 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 KFM65998.1 - 0.22 11.6 7.9 0.24 11.5 6.0 2.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Phasin PF05597.11 KFM65998.1 - 0.26 11.3 5.0 0.55 10.2 5.0 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HscB_4_cys PF18256.1 KFM65998.1 - 0.37 10.6 4.8 0.67 9.8 4.8 1.4 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif TMPIT PF07851.13 KFM65998.1 - 0.4 9.9 1.2 0.7 9.1 1.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran_CTD PF16326.5 KFM65998.1 - 0.68 10.2 3.5 1.8 8.9 0.7 2.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF5446 PF17522.2 KFM65998.1 - 0.73 10.1 7.5 1.9 8.7 1.0 3.0 2 1 1 3 3 2 0 Family of unknown function (DUF5446) FlaC_arch PF05377.11 KFM65998.1 - 0.91 10.0 8.4 2 8.8 6.2 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Med9 PF07544.13 KFM65998.1 - 3.4 7.8 7.1 0.85 9.8 3.0 2.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF5082 PF16888.5 KFM65998.1 - 8 6.8 12.1 15 5.9 1.6 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) DUF5531 PF17671.1 KFM65999.1 - 0.018 14.9 0.4 0.032 14.1 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5531) Mucin PF01456.17 KFM65999.1 - 0.022 14.8 2.4 0.028 14.4 2.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MotB_plug PF13677.6 KFM65999.1 - 0.36 10.5 2.1 0.74 9.5 2.1 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB DUF19 PF01579.18 KFM66000.1 - 0.0002 21.2 10.1 0.00023 21.0 10.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF19) NRN1 PF15056.6 KFM66000.1 - 0.015 15.4 1.3 0.81 9.8 0.1 2.2 1 1 1 2 2 2 0 Neuritin protein family DUF1397 PF07165.11 KFM66000.1 - 0.12 11.7 8.9 0.056 12.9 2.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1397) G-patch PF01585.23 KFM66001.1 - 5.9e-13 48.5 2.5 5.9e-13 48.5 2.5 2.4 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 KFM66001.1 - 0.00013 21.7 0.0 0.00029 20.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP PF17069.5 KFM66001.1 - 4.8 6.7 20.8 7.8 6.0 20.8 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CDC45 PF02724.14 KFM66001.1 - 5.5 5.2 8.3 6.9 4.8 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PRIMA1 PF16101.5 KFM66001.1 - 5.8 7.0 9.0 2.2 8.3 3.8 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 zf-C3HC4_2 PF13923.6 KFM66002.1 - 6.2e-11 42.0 8.4 8.3e-11 41.6 8.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM66002.1 - 8.2e-10 38.4 9.5 1.1e-09 37.9 9.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM66002.1 - 3.6e-07 30.4 8.1 4.9e-07 30.0 8.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM66002.1 - 9.9e-07 28.5 7.9 1.2e-06 28.2 7.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM66002.1 - 6.7e-06 26.3 3.9 1.1e-05 25.6 3.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM66002.1 - 0.00022 21.1 9.7 0.00041 20.3 9.7 1.4 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM66002.1 - 0.0009 19.2 8.7 0.0015 18.5 8.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM66002.1 - 0.001 19.2 8.9 0.0021 18.2 8.9 1.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFM66002.1 - 0.0016 18.3 6.8 0.0023 17.7 6.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KFM66002.1 - 0.0023 17.8 2.7 0.0028 17.5 2.7 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFM66002.1 - 0.013 15.6 5.3 0.018 15.1 5.3 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KFM66002.1 - 0.017 15.1 1.6 0.023 14.7 1.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mononeg_RNA_pol PF00946.19 KFM66002.1 - 0.038 11.7 0.0 0.043 11.5 0.0 1.0 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase zf-Nse PF11789.8 KFM66002.1 - 0.05 13.4 3.8 0.074 12.9 3.8 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 KFM66002.1 - 0.075 13.2 2.9 0.11 12.6 2.9 1.4 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-P11 PF03854.14 KFM66002.1 - 0.25 11.1 6.2 0.38 10.5 6.2 1.3 1 0 0 1 1 1 0 P-11 zinc finger zinc-ribbons_6 PF07191.12 KFM66002.1 - 0.38 10.8 6.0 0.77 9.8 6.1 1.5 1 1 0 1 1 1 0 zinc-ribbons zf-RING_4 PF14570.6 KFM66002.1 - 0.44 10.4 9.1 1.4 8.8 9.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Fer2 PF00111.27 KFM66002.1 - 0.6 10.1 6.1 1.7 8.7 2.5 2.5 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DZR PF12773.7 KFM66002.1 - 1 9.4 6.7 2.8 8.0 6.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_5 PF17121.5 KFM66002.1 - 4.5 7.2 9.0 15 5.6 9.0 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Auto_anti-p27 PF06677.12 KFM66002.1 - 9.8 6.4 8.8 7.4 6.8 4.6 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CBS PF00571.28 KFM66003.1 - 7.2e-32 109.6 4.6 3e-10 40.4 0.2 4.4 4 0 0 4 4 4 4 CBS domain DDE_3 PF13358.6 KFM66004.1 - 3.8e-13 49.4 0.0 5.9e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66004.1 - 6.8e-06 26.2 0.1 1.6e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_3 PF01381.22 KFM66004.1 - 0.014 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_23 PF13384.6 KFM66004.1 - 0.034 13.9 0.1 0.2 11.5 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 KFM66004.1 - 0.056 13.6 0.2 0.16 12.1 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM66005.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66005.1 - 6.2e-13 48.7 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66005.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66005.1 - 0.0025 17.6 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66005.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain IRF PF00605.17 KFM66006.1 - 1.9e-06 28.1 0.0 3.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Ets PF00178.22 KFM66006.1 - 0.15 12.6 0.9 0.53 10.8 0.9 1.9 1 1 0 1 1 1 0 Ets-domain Ribosomal_L5e PF17144.4 KFM66007.1 - 3.2e-90 300.4 0.3 4.4e-90 299.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KFM66007.1 - 1.1e-31 109.6 1.4 2e-31 108.8 1.4 1.5 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DUF1476 PF07345.11 KFM66007.1 - 0.034 14.5 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta THUMP PF02926.17 KFM66007.1 - 0.11 12.6 0.9 11 6.1 0.0 2.6 2 0 0 2 2 2 0 THUMP domain NRDE-2 PF08424.10 KFM66008.1 - 1.4e-05 24.4 0.5 0.00089 18.5 0.5 3.0 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference Suf PF05843.14 KFM66008.1 - 0.00056 20.0 0.0 0.00099 19.2 0.0 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KFM66008.1 - 0.00094 19.8 0.0 2.4 9.2 0.0 3.4 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM66008.1 - 0.027 13.7 0.0 0.084 12.1 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFM66008.1 - 0.056 13.4 0.4 1.8 8.6 0.1 2.3 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 KFM66009.1 - 1.2e-08 35.0 0.1 0.47 11.4 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM66009.1 - 4.4e-08 32.6 1.0 0.14 12.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFM66009.1 - 8.9e-07 28.9 0.9 0.021 14.8 0.5 3.1 2 1 0 2 2 2 2 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 KFM66009.1 - 3.5e-06 26.8 0.3 0.049 13.9 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM66009.1 - 0.0008 19.7 0.0 0.13 12.5 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 KFM66009.1 - 0.00093 19.3 0.2 0.0026 17.8 0.1 1.8 1 1 1 2 2 2 1 Suppressor of forked protein (Suf) TPR_15 PF13429.6 KFM66009.1 - 0.0053 16.0 0.1 0.52 9.5 0.1 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat CKAP2_C PF15297.6 KFM66009.1 - 0.018 14.2 0.8 0.075 12.1 0.1 1.9 1 1 1 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus DALR_1 PF05746.15 KFM66009.1 - 0.022 14.9 0.1 0.081 13.1 0.1 2.1 1 1 0 1 1 1 0 DALR anticodon binding domain MIT PF04212.18 KFM66009.1 - 0.097 12.8 1.0 0.68 10.0 0.1 2.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 KFM66010.1 - 0.0039 16.6 0.6 0.006 16.0 0.6 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP HAT PF02184.16 KFM66010.1 - 0.21 11.6 1.1 0.97 9.5 0.3 2.5 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat TPR_8 PF13181.6 KFM66010.1 - 3.7 8.0 4.9 2 8.9 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Arc_C PF18162.1 KFM66014.1 - 2.5e-06 27.2 0.5 6.3e-06 26.0 0.5 1.7 1 0 0 1 1 1 1 Arc C-lobe Lipocalin PF00061.23 KFM66015.1 - 8.7e-08 32.5 0.2 9.4e-08 32.4 0.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFM66015.1 - 3.8e-05 23.6 0.0 4.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain eIF-4B PF06273.11 KFM66016.1 - 0.26 10.3 2.9 1.3 8.0 3.7 1.6 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B CCDC-167 PF15188.6 KFM66016.1 - 0.51 10.7 0.0 0.51 10.7 0.0 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 SPT16 PF08644.11 KFM66016.1 - 1.1 9.4 4.8 6.5 6.9 2.9 2.2 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Pkinase PF00069.25 KFM66017.1 - 1.4e-21 77.1 0.2 2.9e-14 53.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM66017.1 - 8.6e-07 28.5 0.0 1.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 KFM66017.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KFM66018.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain HGTP_anticodon2 PF12745.7 KFM66019.1 - 4.7e-06 26.3 2.0 1.1e-05 25.1 1.7 1.7 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs HGTP_anticodon PF03129.20 KFM66019.1 - 0.0012 19.0 0.0 0.0058 16.8 0.0 2.0 1 1 1 2 2 2 1 Anticodon binding domain tRNA-synt_His PF13393.6 KFM66019.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Cadherin PF00028.17 KFM66021.1 - 2.6e-12 47.0 0.8 1e-07 32.3 0.0 3.2 3 0 0 3 3 3 2 Cadherin domain Laminin_G_3 PF13385.6 KFM66021.1 - 3.6e-09 36.9 0.0 7.2e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Toxin_R_bind_N PF07953.12 KFM66021.1 - 9.9e-06 25.4 0.1 1.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Clostridium neurotoxin, N-terminal receptor binding Laminin_G_2 PF02210.24 KFM66021.1 - 0.00038 21.0 0.0 0.0013 19.3 0.0 1.9 1 0 0 1 1 1 1 Laminin G domain Glyco_hydro_16 PF00722.21 KFM66021.1 - 0.044 13.3 2.2 0.089 12.3 2.2 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 16 TMEM154 PF15102.6 KFM66021.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Cadherin_C_2 PF16492.5 KFM66021.1 - 0.091 13.5 0.0 0.24 12.2 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal FAM176 PF14851.6 KFM66021.1 - 0.13 11.9 3.7 0.59 9.8 3.7 2.0 1 1 0 1 1 1 0 FAM176 family HTH_Tnp_Tc3_2 PF01498.18 KFM66022.1 - 1e-11 44.9 0.7 2.5e-11 43.6 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66022.1 - 8.1e-08 32.1 0.1 3.4e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66022.1 - 0.0075 16.0 0.7 0.33 10.7 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM66022.1 - 0.0089 15.9 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Tc3 transposase HTH_24 PF13412.6 KFM66022.1 - 0.11 12.1 0.1 5.4 6.7 0.1 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 KFM66023.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66023.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66023.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66023.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66023.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66024.1 - 4e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66024.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66024.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66024.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66024.1 - 0.026 14.7 0.9 0.085 13.0 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM66024.1 - 2.1 9.0 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF2254 PF10011.9 KFM66026.1 - 0.1 11.4 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF2946 PF11162.8 KFM66027.1 - 0.15 12.8 5.4 0.21 12.2 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Innate_immun PF12782.7 KFM66027.1 - 2.1 7.8 10.9 2.6 7.5 10.9 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family ThiF PF00899.21 KFM66028.1 - 1.3e-48 165.5 0.0 1.8e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 KFM66028.1 - 4.8e-05 23.0 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM66028.1 - 0.031 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFM66028.1 - 0.035 13.8 0.3 0.33 10.6 0.2 2.4 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KFM66028.1 - 0.07 13.4 0.7 0.29 11.4 0.7 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KFM66028.1 - 0.074 12.3 0.3 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain VSP PF03302.13 KFM66028.1 - 0.1 11.5 0.2 0.15 10.9 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4342 PF14242.6 KFM66028.1 - 0.26 11.3 1.4 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) ThiF PF00899.21 KFM66029.1 - 2.8e-16 59.6 0.0 3.1e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 ThiF family Mic1 PF07035.12 KFM66030.1 - 1e-58 197.5 6.5 1e-58 197.5 6.5 1.9 1 1 1 2 2 2 1 Colon cancer-associated protein Mic1-like Fanconi_A_N PF15865.5 KFM66030.1 - 0.002 17.6 2.9 0.002 17.6 2.9 1.6 1 1 0 1 1 1 1 Fanconi anaemia group A protein N terminus Siva PF05458.12 KFM66031.1 - 6.8e-14 51.9 32.1 3.6e-08 33.3 0.2 2.1 1 1 1 2 2 2 2 Cd27 binding protein (Siva) Ras PF00071.22 KFM66032.1 - 3.1e-62 208.9 1.9 3.6e-62 208.7 1.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM66032.1 - 5.3e-34 117.0 1.4 8.6e-34 116.3 1.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM66032.1 - 3e-15 56.1 0.3 3.7e-15 55.8 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFM66032.1 - 9.9e-06 25.1 0.2 5.4e-05 22.7 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFM66032.1 - 7.3e-05 22.4 0.2 0.00026 20.6 0.1 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFM66032.1 - 8.8e-05 22.0 0.4 0.00012 21.5 0.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KFM66032.1 - 0.00011 21.8 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KFM66032.1 - 0.00012 22.1 0.1 0.00019 21.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM66032.1 - 0.0018 18.2 0.2 0.19 11.7 0.0 2.3 1 1 0 2 2 2 1 RsgA GTPase DUF2757 PF10955.8 KFM66032.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) AAA_24 PF13479.6 KFM66032.1 - 0.045 13.5 0.4 0.12 12.1 0.4 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFM66032.1 - 0.077 12.7 0.1 4.1 7.2 0.0 2.5 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KFM66032.1 - 0.16 12.3 0.0 0.24 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain CNH PF00780.22 KFM66033.1 - 0.0043 16.7 0.0 0.0048 16.5 0.0 1.0 1 0 0 1 1 1 1 CNH domain NTNH_C PF08470.10 KFM66033.1 - 0.13 12.1 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal ABM PF03992.16 KFM66035.1 - 0.05 13.7 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Med27 PF11571.8 KFM66036.1 - 7.5e-29 99.9 0.8 1.9e-28 98.6 0.2 1.9 2 0 0 2 2 2 1 Mediator complex subunit 27 Adaptin_N PF01602.20 KFM66037.1 - 1.2e-46 159.4 18.9 1.4e-46 159.2 18.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 KFM66037.1 - 3.6e-06 26.8 0.6 0.042 14.1 0.1 3.3 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 KFM66037.1 - 1.9e-05 25.0 0.2 0.00015 22.1 0.3 2.5 1 1 1 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 KFM66037.1 - 0.011 16.2 0.6 0.12 12.9 0.5 2.6 2 1 1 3 3 3 0 HEAT-like repeat ECH_1 PF00378.20 KFM66037.1 - 0.065 12.5 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Herpes_U59 PF04529.12 KFM66037.1 - 0.15 11.1 5.1 1 8.3 0.2 2.8 2 1 0 3 3 3 0 Herpesvirus U59 protein RTP1_C1 PF10363.9 KFM66037.1 - 1.3 9.2 7.4 66 3.7 1.3 4.1 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Neur_chan_memb PF02932.16 KFM66039.1 - 5.7e-30 105.1 2.3 2.9e-25 89.7 0.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM66040.1 - 8.3e-29 100.6 0.1 9.1e-29 100.5 0.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain ATG13 PF10033.9 KFM66041.1 - 1.1e-06 28.5 1.4 0.015 15.0 0.6 3.1 1 1 1 2 2 2 2 Autophagy-related protein 13 zf-C3Hc3H PF13891.6 KFM66043.1 - 7.4e-16 58.3 4.6 9.4e-16 57.9 4.6 1.2 1 0 0 1 1 1 1 Potential DNA-binding domain CxC6 PF18721.1 KFM66043.1 - 0.47 10.8 3.9 0.78 10.0 3.9 1.4 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases AAA_lid_10 PF17872.1 KFM66045.1 - 0.056 13.6 0.0 0.059 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA lid domain Peptidase_C50 PF03568.17 KFM66047.1 - 8.9e-60 202.9 0.0 1.2e-59 202.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 KFM66047.1 - 4.8e-05 22.9 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 CHAT domain HTH_AraC PF00165.23 KFM66047.1 - 0.037 14.2 0.4 0.88 9.8 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Piwi PF02171.17 KFM66048.1 - 3.9e-83 279.2 0.0 5.7e-83 278.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KFM66048.1 - 4.2e-16 59.8 0.4 1.8e-15 57.8 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 KFM66048.1 - 1.8e-13 50.5 0.2 3.7e-13 49.4 0.2 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KFM66048.1 - 2.8e-11 42.9 0.3 1.7e-10 40.4 0.1 2.3 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoMid PF16487.5 KFM66048.1 - 3.6e-10 39.9 0.1 5.6e-09 36.1 0.0 2.6 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 KFM66048.1 - 0.06 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Argonaute linker 2 domain Ank_2 PF12796.7 KFM66051.1 - 1.1e-34 118.9 1.2 7e-15 55.4 0.1 4.4 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM66051.1 - 1.3e-32 111.7 4.1 6e-10 39.5 0.0 7.5 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM66051.1 - 4.1e-30 100.4 9.7 9e-05 22.6 0.0 8.7 8 1 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KFM66051.1 - 5.5e-27 93.0 8.8 0.0012 19.2 0.1 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFM66051.1 - 3.2e-18 65.6 8.6 0.00068 19.9 0.1 7.2 5 2 2 7 7 7 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFM66051.1 - 0.00077 19.8 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 SOCS box LisH PF08513.11 KFM66051.1 - 7.2 6.7 8.0 5.1 7.2 0.0 3.8 4 0 0 4 4 4 0 LisH HTH_Tnp_Tc3_2 PF01498.18 KFM66052.1 - 4.2e-16 59.0 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66052.1 - 1.1e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66052.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66052.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66052.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DUF3678 PF12435.8 KFM66055.1 - 0.89 9.0 6.9 4.6 6.7 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) RA PF00788.23 KFM66056.1 - 0.0007 20.2 0.1 0.021 15.5 0.1 2.5 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain HTH_Tnp_Tc3_2 PF01498.18 KFM66057.1 - 4.2e-16 58.9 3.4 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66057.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66057.1 - 9.5e-08 31.7 0.8 4e-07 29.7 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66057.1 - 0.0013 18.4 0.3 0.0037 17.0 0.3 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66057.1 - 0.012 15.7 0.3 0.037 14.2 0.3 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.6 KFM66058.1 - 5.8e-16 58.6 0.1 5.9e-15 55.3 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66058.1 - 1.4e-10 41.2 1.0 2.8e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Glyco_hydro_18 PF00704.28 KFM66059.1 - 1.6e-170 566.8 7.4 1.2e-86 291.2 0.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 CBM_14 PF01607.24 KFM66059.1 - 2.1e-06 27.8 1.1 4.5e-06 26.7 1.1 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain RNA_pol_Rpb6 PF01192.22 KFM66060.1 - 3.9e-14 52.3 0.1 3.9e-14 52.3 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb6 LepB_N PF18640.1 KFM66060.1 - 0.13 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 LepB N-terminal domain CP2 PF04516.15 KFM66062.1 - 2.5e-58 197.1 0.0 3.8e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor DDE_3 PF13358.6 KFM66064.1 - 8.2e-16 58.1 0.1 1e-14 54.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66064.1 - 1.7e-10 41.0 1.0 3.8e-10 39.9 1.0 1.6 1 0 0 1 1 1 1 Transposase DUF229 PF02995.17 KFM66065.1 - 1.1e-137 459.6 5.1 1.5e-137 459.2 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 KFM66065.1 - 1.5e-05 24.6 0.0 3.9e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Sulfatase HAP1_N PF04849.13 KFM66066.1 - 2.5e-101 338.9 27.5 3.3e-101 338.5 27.5 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.8 KFM66066.1 - 2.1e-05 24.7 0.1 2.1e-05 24.7 0.1 2.9 2 1 1 3 3 3 1 Kinesin associated protein Rootletin PF15035.6 KFM66066.1 - 0.019 15.0 0.7 0.019 15.0 0.7 2.6 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion TSC22 PF01166.18 KFM66066.1 - 0.68 10.3 15.3 6 7.3 0.9 4.9 4 1 1 5 5 5 0 TSC-22/dip/bun family DUF724 PF05266.14 KFM66066.1 - 2 8.2 16.5 0.39 10.5 6.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Leu_zip PF15294.6 KFM66066.1 - 2.2 7.8 24.8 0.2 11.1 16.2 2.5 1 1 1 2 2 2 0 Leucine zipper ADIP PF11559.8 KFM66066.1 - 3.2 7.8 29.7 2.2 8.4 17.0 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding APC_N_CC PF16689.5 KFM66066.1 - 3.7 7.7 8.4 19 5.4 1.4 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain DDE_3 PF13358.6 KFM66068.1 - 2e-10 40.6 0.0 2.7e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66068.1 - 4e-09 36.6 0.8 8e-09 35.6 0.8 1.5 1 0 0 1 1 1 1 Transposase Cys_box PF17869.1 KFM66068.1 - 0.069 13.3 0.6 0.92 9.7 0.2 2.5 2 0 0 2 2 2 0 Anosmin cysteine rich domain HTH_33 PF13592.6 KFM66068.1 - 0.15 11.7 1.0 0.33 10.6 0.7 1.7 1 1 0 1 1 1 0 Winged helix-turn helix Defensin_big PF14862.6 KFM66070.1 - 0.031 14.6 0.5 0.059 13.7 0.5 1.4 1 1 0 1 1 1 0 Big defensin ESP PF16590.5 KFM66071.1 - 0.15 12.3 0.0 0.19 12.0 0.0 1.3 1 1 0 1 1 1 0 Exocrine gland-secreting peptide DDE_Tnp_1_7 PF13843.6 KFM66072.1 - 3.6e-87 292.9 1.2 4.6e-87 292.6 1.2 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM66072.1 - 4.3e-06 27.4 8.0 4.3e-06 27.4 8.0 1.9 2 0 0 2 2 2 1 DDE_Tnp_1-like zinc-ribbon zf-B_box PF00643.24 KFM66072.1 - 0.52 10.5 7.0 1.1 9.5 7.0 1.5 1 0 0 1 1 1 0 B-box zinc finger C1_2 PF03107.16 KFM66072.1 - 1.8 8.9 7.4 4.7 7.6 7.4 1.8 1 1 0 1 1 1 0 C1 domain ORC4_C PF14629.6 KFM66073.1 - 3.3e-42 144.3 1.8 5e-42 143.7 1.8 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KFM66073.1 - 9.8e-12 45.6 0.1 4e-11 43.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFM66073.1 - 6e-09 36.0 0.7 2.6e-08 33.9 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KFM66073.1 - 7.4e-09 36.0 0.3 4e-08 33.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFM66073.1 - 2.7e-08 34.3 0.0 5.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KFM66073.1 - 5.7e-05 23.1 1.1 0.00023 21.2 0.5 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFM66073.1 - 9.3e-05 22.5 0.1 0.0004 20.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain DAP3 PF10236.9 KFM66073.1 - 0.00022 20.5 0.1 0.021 14.0 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KFM66073.1 - 0.0025 17.5 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 KFM66073.1 - 0.005 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KFM66073.1 - 0.0086 15.6 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region Peroxin-22 PF12827.7 KFM66073.1 - 0.011 15.7 0.9 0.27 11.2 0.1 2.9 3 1 0 3 3 3 0 Peroxisomal biogenesis protein family RNA12 PF10443.9 KFM66073.1 - 0.014 14.2 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein Roc PF08477.13 KFM66073.1 - 0.015 15.5 0.1 0.17 12.1 0.0 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KFM66073.1 - 0.019 15.5 0.3 0.11 13.0 0.1 2.1 2 1 0 2 2 2 0 ABC transporter SRPRB PF09439.10 KFM66073.1 - 0.022 14.2 0.2 0.077 12.4 0.2 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 KFM66073.1 - 0.033 14.5 0.0 0.11 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFM66073.1 - 0.039 14.0 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ORC2 PF04084.14 KFM66073.1 - 0.039 12.9 0.5 0.073 12.0 0.3 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 2 SMC_N PF02463.19 KFM66073.1 - 0.043 13.3 0.4 0.28 10.6 0.0 2.1 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain TniB PF05621.11 KFM66073.1 - 0.049 13.0 0.1 0.14 11.6 0.1 1.8 1 1 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 KFM66073.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KFM66073.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFM66073.1 - 0.1 13.1 1.3 0.38 11.2 1.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM66073.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFM66073.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 KFM66073.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.16 KFM66074.1 - 1e-24 87.2 7.8 1.6e-24 86.6 7.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM66074.1 - 9.4e-08 31.3 4.2 1.1e-07 31.1 4.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KFM66074.1 - 0.0027 17.1 1.3 0.0046 16.3 1.3 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB HTH_Tnp_Tc3_2 PF01498.18 KFM66075.1 - 2.7e-16 59.6 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66075.1 - 3.8e-14 52.7 0.0 6.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66075.1 - 4.9e-07 29.4 1.6 6.5e-07 29.0 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66075.1 - 0.0023 17.7 0.6 0.0069 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66075.1 - 0.027 14.6 0.4 0.083 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM66075.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain MFS_1 PF07690.16 KFM66076.1 - 2.4e-43 148.4 28.8 2.2e-41 142.0 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFM66076.1 - 9.6e-06 25.1 1.4 9.6e-06 25.1 1.4 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1772 PF08592.11 KFM66076.1 - 0.26 11.6 0.1 0.26 11.6 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) HTH_Tnp_Tc3_2 PF01498.18 KFM66077.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66077.1 - 1e-13 51.2 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66077.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66077.1 - 0.0023 17.7 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66077.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain 7tm_1 PF00001.21 KFM66078.1 - 9.3e-23 80.9 0.0 1.1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM66078.1 - 0.00024 20.6 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM72 PF16054.5 KFM66078.1 - 0.06 13.0 0.1 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 72 PRE_C2HC PF07530.11 KFM66079.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Associated with zinc fingers zf-CCHC_6 PF15288.6 KFM66079.1 - 0.041 13.7 1.7 0.041 13.7 1.7 2.5 2 0 0 2 2 2 0 Zinc knuckle zinc_ribbon_4 PF13717.6 KFM66079.1 - 0.3 11.0 0.2 0.3 11.0 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_4 PF14392.6 KFM66079.1 - 3 7.6 12.9 1.1 9.0 1.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Neur_chan_memb PF02932.16 KFM66080.1 - 4.9e-61 206.8 0.2 6.1e-61 206.5 0.2 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM66080.1 - 5.6e-13 48.8 0.0 8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.9 KFM66080.1 - 0.021 14.2 3.0 0.053 12.9 0.9 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF2418 PF10332.9 KFM66080.1 - 1.5 9.4 4.2 0.41 11.2 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) HTH_Tnp_Tc3_2 PF01498.18 KFM66082.1 - 4.5e-16 58.8 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66082.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66082.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66082.1 - 0.0027 17.5 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66082.1 - 0.03 14.4 0.4 0.092 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM66082.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66083.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66083.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 KFM66084.1 - 7.4e-35 119.0 0.0 1.1e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM66084.1 - 7.7e-33 112.9 0.0 1.6e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Tic22 PF04278.12 KFM66084.1 - 0.12 11.7 0.0 0.38 10.1 0.0 1.5 1 1 1 2 2 2 0 Tic22-like family RSN1_TM PF13967.6 KFM66086.1 - 1.1e-16 60.9 3.5 1e-15 57.8 3.5 2.0 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFM66088.1 - 0.0089 16.3 0.0 0.0089 16.3 0.0 1.0 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 KFM66089.1 - 4.3e-44 150.9 22.6 4.3e-44 150.9 22.6 1.4 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate DUF962 PF06127.11 KFM66089.1 - 7 6.8 7.8 15 5.7 4.4 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF962) HTH_Tnp_Tc3_2 PF01498.18 KFM66091.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66091.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66091.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66091.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66091.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66092.1 - 1.9e-17 63.3 2.0 6.1e-16 58.4 2.2 2.6 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM66092.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66092.1 - 2.1e-07 30.6 1.2 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66092.1 - 0.0027 17.5 0.6 0.008 15.9 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66092.1 - 2.3 8.9 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain CRAL_TRIO PF00650.20 KFM66094.1 - 0.074 12.8 0.0 10 5.8 0.0 2.6 2 0 0 2 2 2 0 CRAL/TRIO domain Phage_TAC_3 PF06896.11 KFM66094.1 - 0.1 13.2 0.1 0.49 11.0 0.0 2.1 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, TAC RhoGEF PF00621.20 KFM66095.1 - 3.2e-37 128.5 5.3 3.2e-37 128.5 5.3 2.1 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.6 KFM66095.1 - 0.001 19.3 0.1 0.0029 17.9 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFM66095.1 - 0.037 14.0 0.9 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 PH domain MSG PF02349.15 KFM66095.1 - 0.56 10.4 4.1 8.7 6.6 0.0 3.4 3 0 0 3 3 3 0 Major surface glycoprotein DHHC PF01529.20 KFM66096.1 - 0.0032 17.6 0.5 0.0034 17.5 0.5 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_3 PF13606.6 KFM66098.1 - 2.9e-08 33.3 0.1 0.00021 21.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFM66098.1 - 6.4e-08 33.0 0.1 4.9e-05 23.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM66098.1 - 7e-08 32.9 0.0 9.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM66098.1 - 9.3e-08 32.2 0.1 3.4e-07 30.4 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM66098.1 - 4.9e-05 23.6 0.0 0.012 16.0 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat DUF2116 PF09889.9 KFM66100.1 - 0.012 15.6 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RRM_1 PF00076.22 KFM66101.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_1 PF00515.28 KFM66102.1 - 1.5e-17 62.5 0.4 2.2e-08 33.6 0.1 2.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM66102.1 - 8.5e-14 51.6 5.0 5.4e-10 39.4 0.8 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM66102.1 - 1.8e-13 49.5 0.1 2.3e-05 24.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM66102.1 - 2.7e-12 46.2 1.7 1.3e-07 31.2 0.0 3.1 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 KFM66102.1 - 3.6e-12 45.5 0.3 1.2e-05 25.1 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM66102.1 - 5.8e-09 35.7 1.3 0.0019 18.4 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM66102.1 - 6.7e-08 33.1 0.0 1.6e-06 28.6 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM66102.1 - 4.4e-07 29.6 0.7 0.019 14.8 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM66102.1 - 3.2e-06 26.8 0.2 0.049 13.7 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM66102.1 - 6.7e-05 23.4 0.0 5.8 8.0 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM66102.1 - 0.0019 18.7 0.1 2.4 8.7 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM66102.1 - 0.0072 15.7 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 MalT-like TPR region DUF410 PF04190.13 KFM66102.1 - 0.028 14.2 0.6 0.21 11.3 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF410) TPR_17 PF13431.6 KFM66104.1 - 3.7e-08 33.2 0.9 0.0021 18.3 0.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM66104.1 - 3.2e-07 29.9 0.3 0.00016 21.3 0.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 KFM66104.1 - 7.4e-06 25.7 0.4 4.3e-05 23.3 0.1 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM66104.1 - 3e-05 23.6 0.6 0.0016 18.2 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM66104.1 - 0.00046 20.8 0.1 0.00062 20.4 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM66104.1 - 0.0038 17.3 0.0 0.031 14.5 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM66104.1 - 0.1 13.5 0.0 0.45 11.5 0.1 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1736 PF08409.11 KFM66105.1 - 1.5e-28 98.5 0.8 2.1e-28 98.1 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) RNA_pol_Rpb1_5 PF04998.17 KFM66109.1 - 6.8e-15 55.2 0.5 8e-15 55.0 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Bromodomain PF00439.25 KFM66110.1 - 9.2e-42 141.0 1.2 8e-20 70.7 0.0 2.8 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KFM66110.1 - 1.1e-28 99.2 2.1 1.6e-28 98.7 0.1 2.4 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Enkurin PF13864.6 KFM66110.1 - 0.44 11.0 15.3 3.1 8.3 7.8 3.2 2 0 0 2 2 2 0 Calmodulin-binding Peptidase_A17 PF05380.13 KFM66111.1 - 8.9e-28 97.3 0.2 2e-27 96.2 0.0 1.6 2 0 0 2 2 2 1 Pao retrotransposon peptidase RT_RNaseH_2 PF17919.1 KFM66111.1 - 0.015 15.3 0.0 0.043 13.9 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF4931 PF16285.5 KFM66111.1 - 0.041 13.2 0.5 0.063 12.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) WD40 PF00400.32 KFM66112.1 - 4.6e-16 58.9 1.9 8.3e-10 39.1 0.3 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM66112.1 - 1.7e-06 28.2 0.0 0.0017 18.6 0.0 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM66112.1 - 0.00024 19.9 0.2 0.25 9.9 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KFM66112.1 - 0.00046 20.1 0.0 0.00064 19.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KFM66112.1 - 0.0037 16.3 0.0 0.9 8.4 0.0 2.0 1 1 1 2 2 2 2 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 KFM66112.1 - 0.032 13.6 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain VID27 PF08553.10 KFM66112.1 - 0.042 12.9 0.0 0.12 11.4 0.0 1.6 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain DDE_3 PF13358.6 KFM66113.1 - 3.5e-14 52.8 0.0 3.7e-13 49.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66113.1 - 2.2e-10 40.7 1.0 4.5e-10 39.6 1.0 1.6 1 0 0 1 1 1 1 Transposase DDE_1 PF03184.19 KFM66113.1 - 8.4e-06 25.5 0.0 3.2e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease WD40 PF00400.32 KFM66114.1 - 5.9e-11 42.7 0.1 0.00011 22.9 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Cytochrome_C7 PF14522.6 KFM66114.1 - 0.058 13.4 0.5 0.071 13.1 0.5 1.2 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Proteasome PF00227.26 KFM66115.1 - 2.1e-23 82.8 0.0 2.5e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KFM66115.1 - 0.038 13.4 0.2 0.064 12.7 0.2 1.4 1 0 0 1 1 1 0 Proteasome beta subunits C terminal CD34_antigen PF06365.12 KFM66117.1 - 0.13 11.8 1.2 0.18 11.4 1.1 1.4 1 1 0 1 1 1 0 CD34/Podocalyxin family RabGAP-TBC PF00566.18 KFM66118.1 - 6.6e-21 75.0 5.7 6.6e-21 75.0 5.7 2.6 3 1 0 3 3 3 1 Rab-GTPase-TBC domain ComZ PF10815.8 KFM66118.1 - 0.029 14.4 0.3 0.08 13.0 0.3 1.8 1 0 0 1 1 1 0 ComZ ATG16 PF08614.11 KFM66118.1 - 0.19 11.9 38.8 0.17 12.1 13.1 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF4510 PF14971.6 KFM66118.1 - 0.63 10.4 7.6 0.078 13.3 2.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) NPV_P10 PF05531.12 KFM66118.1 - 0.94 10.0 8.3 0.51 10.8 1.1 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ERM PF00769.19 KFM66118.1 - 1.3 8.8 41.7 4.1 7.2 40.2 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Activator-TraM PF11657.8 KFM66118.1 - 5.1 6.9 11.9 0.25 11.2 5.2 2.3 2 1 1 3 3 3 0 Transcriptional activator TraM APG6_N PF17675.1 KFM66118.1 - 5.1 7.6 46.7 2.3 8.7 12.2 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF2161 PF09929.9 KFM66118.1 - 6.3 7.0 7.2 0.63 10.2 0.9 2.5 3 0 0 3 3 3 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) DUF3694 PF12473.8 KFM66119.1 - 1.7e-29 103.4 0.0 6.8e-29 101.5 0.0 1.9 1 1 0 1 1 1 1 Kinesin protein RabGAP-TBC PF00566.18 KFM66119.1 - 1.7e-12 47.5 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BESS PF02944.20 KFM66121.1 - 1.2e-09 37.9 3.5 4.4e-09 36.0 3.5 2.1 1 0 0 1 1 1 1 BESS motif TMEM126 PF07114.11 KFM66121.1 - 0.31 10.4 2.3 10 5.5 0.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 126 Fumble PF03630.14 KFM66121.1 - 0.33 10.1 1.4 11 5.0 0.2 2.8 2 2 0 2 2 2 0 Fumble Plk4_PB1 PF18190.1 KFM66121.1 - 0.67 10.1 5.1 22 5.2 0.3 3.3 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 1 MA3 PF02847.17 KFM66122.1 - 3.7e-30 104.2 2.7 3e-19 69.1 0.0 3.5 3 0 0 3 3 3 2 MA3 domain MIF4G PF02854.19 KFM66122.1 - 4.7e-26 91.7 18.5 4.9e-26 91.7 2.3 4.4 4 1 1 5 5 5 2 MIF4G domain W2 PF02020.18 KFM66122.1 - 1.4e-14 54.0 0.3 6.2e-14 51.9 0.3 2.2 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon TIR_3 PF18567.1 KFM66122.1 - 0.0029 17.6 1.3 0.25 11.3 0.2 2.7 2 0 0 2 2 2 1 Toll/interleukin-1 receptor domain eIF_4EBP PF05456.11 KFM66122.1 - 0.14 12.1 2.4 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) NYN PF01936.18 KFM66123.1 - 1.3e-16 61.3 2.3 4.3e-16 59.7 2.3 1.9 1 0 0 1 1 1 1 NYN domain Helicase_C PF00271.31 KFM66123.1 - 1.6e-16 60.6 1.8 5.9e-16 58.8 0.1 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain IBR PF01485.21 KFM66123.1 - 2.1e-15 56.7 15.8 2e-10 40.7 1.8 4.1 4 0 0 4 4 2 2 IBR domain, a half RING-finger domain HA2 PF04408.23 KFM66123.1 - 2.7e-12 46.9 0.0 1.4e-11 44.7 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFM66123.1 - 8.9e-08 32.4 0.7 2.4e-07 31.0 0.0 2.2 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFM66123.1 - 4.3e-05 23.4 1.4 0.00013 21.8 1.4 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.22 KFM66123.1 - 0.0002 21.1 1.6 9.3 6.2 0.0 5.9 6 0 0 6 6 6 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KFM66123.1 - 0.0024 18.2 6.0 0.0024 18.2 6.0 4.6 3 1 1 4 4 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM66123.1 - 0.0056 16.5 4.1 0.0056 16.5 4.1 3.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) KH_1 PF00013.29 KFM66123.1 - 0.014 15.2 0.1 2.8 7.8 0.0 3.9 3 0 0 3 3 3 0 KH domain AAA_30 PF13604.6 KFM66123.1 - 0.045 13.5 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain HMA PF00403.26 KFM66123.1 - 0.098 13.1 0.4 0.5 10.8 0.4 2.3 1 0 0 1 1 1 0 Heavy-metal-associated domain AAA_22 PF13401.6 KFM66123.1 - 0.13 12.5 0.4 0.67 10.2 0.1 2.5 3 0 0 3 3 2 0 AAA domain SLS PF14611.6 KFM66123.1 - 0.14 11.9 6.2 0.24 11.2 0.0 3.9 4 1 0 4 4 4 0 Mitochondrial inner-membrane-bound regulator Zn-ribbon_8 PF09723.10 KFM66123.1 - 2.6 8.2 5.5 0.64 10.2 0.0 3.0 2 1 0 2 2 1 0 Zinc ribbon domain Astacin PF01400.24 KFM66124.1 - 1.3e-53 181.5 0.0 1.7e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFM66124.1 - 0.043 12.8 0.1 0.063 12.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M8 PF01457.16 KFM66124.1 - 0.044 12.5 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Leishmanolysin Peptidase_M10 PF00413.24 KFM66124.1 - 0.045 13.6 0.4 0.14 12.0 0.5 1.6 1 1 0 1 1 1 0 Matrixin DUF3810 PF12725.7 KFM66124.1 - 0.092 12.1 1.0 0.16 11.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Transposase_1 PF01359.18 KFM66128.1 - 1e-23 82.9 0.7 1.9e-23 82.1 0.7 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM66128.1 - 1.5e-05 24.8 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM66128.1 - 0.00027 21.5 0.0 0.00095 19.7 0.0 2.1 1 1 0 1 1 1 1 Homeodomain-like domain HTH_48 PF17906.1 KFM66128.1 - 0.00032 20.7 0.3 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 HTH domain in Mos1 transposase Proteasom_PSMB PF10508.9 KFM66129.1 - 0.012 14.1 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit GerD PF17898.1 KFM66129.1 - 0.12 12.3 0.2 0.92 9.5 0.1 2.0 2 0 0 2 2 2 0 Spore germination GerD central core domain RRM_1 PF00076.22 KFM66130.1 - 4.9e-29 99.9 0.1 4.9e-16 58.3 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 KFM66130.1 - 2e-26 91.9 2.0 4.9e-26 90.7 2.0 1.7 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 KFM66130.1 - 0.00085 19.4 0.0 0.0047 17.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 KFM66130.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif PUA PF01472.20 KFM66130.1 - 0.037 14.0 0.2 0.25 11.3 0.1 2.3 2 0 0 2 2 2 0 PUA domain Amidase PF01425.21 KFM66132.1 - 3.5e-74 250.4 0.0 5.2e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Amidase Zn_ribbon_SprT PF17283.2 KFM66133.1 - 0.0028 17.5 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 2 SprT-like zinc ribbon domain Amidase PF01425.21 KFM66134.1 - 7e-47 160.4 0.0 1.2e-46 159.6 0.0 1.4 1 1 0 1 1 1 1 Amidase Cyclotide PF03784.13 KFM66134.1 - 0.28 11.3 2.0 0.56 10.3 0.3 2.2 2 0 0 2 2 2 0 Cyclotide family KOG2701 PF09762.9 KFM66135.1 - 4.8e-76 254.9 0.0 4.8e-76 254.9 0.0 4.4 2 1 2 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) FUSC PF04632.12 KFM66135.1 - 5.6 5.4 9.2 2 6.9 5.3 2.0 2 1 0 2 2 2 0 Fusaric acid resistance protein family KapB PF08810.10 KFM66135.1 - 5.9 7.1 13.2 7.8 6.7 1.6 3.7 2 1 1 3 3 3 0 Kinase associated protein B AAA_22 PF13401.6 KFM66135.1 - 6.9 6.9 7.1 3.4 8.0 0.7 2.8 2 1 0 2 2 2 0 AAA domain Integrin_alpha2 PF08441.12 KFM66138.1 - 8.4e-106 354.6 0.2 9.9e-106 354.4 0.2 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFM66138.1 - 1.2e-23 82.8 23.8 5.2e-10 39.3 2.0 4.1 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.6 KFM66138.1 - 1e-13 51.6 12.7 3.2e-07 30.8 0.1 3.3 1 1 3 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella LYRIC PF15686.5 KFM66138.1 - 0.0017 18.0 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family Integrin_alpha PF00357.20 KFM66138.1 - 0.022 14.7 4.2 0.062 13.3 4.2 1.8 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region DUF2207 PF09972.9 KFM66138.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HisK_sensor PF18698.1 KFM66138.1 - 0.2 12.0 0.6 6.3 7.2 0.1 2.6 2 0 0 2 2 2 0 Histidine kinase sensor domain Mucin2_WxxW PF13330.6 KFM66140.1 - 2.4e-127 416.1 98.7 1.9e-23 83.1 1.6 11.5 12 1 1 13 13 13 8 Mucin-2 protein WxxW repeating region VWD PF00094.25 KFM66140.1 - 8.1e-105 347.9 9.1 1.2e-29 103.6 0.0 4.5 4 0 0 4 4 4 4 von Willebrand factor type D domain F5_F8_type_C PF00754.25 KFM66140.1 - 7.1e-70 233.0 4.6 1.3e-22 80.2 0.5 3.4 3 0 0 3 3 3 3 F5/8 type C domain C8 PF08742.11 KFM66140.1 - 3.3e-33 113.9 41.1 1.6e-19 70.1 10.0 12.2 10 2 1 11 11 11 5 C8 domain TIL PF01826.17 KFM66140.1 - 4.6e-33 113.3 135.8 2e-11 44.0 16.0 19.3 20 1 1 21 21 21 7 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.13 KFM66140.1 - 1e-07 31.6 25.2 2.5e-06 27.1 8.0 14.2 13 2 1 14 14 14 2 Pacifastin inhibitor (LCMII) VWC PF00093.18 KFM66140.1 - 0.0018 18.5 6.8 0.0018 18.5 6.8 22.5 17 6 3 20 20 20 6 von Willebrand factor type C domain Cation_efflux PF01545.21 KFM66141.1 - 6.6e-10 39.1 17.2 1.1e-09 38.3 17.2 1.3 1 1 0 1 1 1 1 Cation efflux family DUF2105 PF09878.9 KFM66141.1 - 0.013 15.2 3.0 0.017 14.8 3.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2105) Peptidase_A22B PF04258.13 KFM66141.1 - 0.21 11.1 6.8 0.4 10.2 6.6 1.6 1 1 0 1 1 1 0 Signal peptide peptidase HTH_Tnp_Tc3_2 PF01498.18 KFM66142.1 - 2.4e-16 59.7 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66142.1 - 9.8e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease I-set PF07679.16 KFM66145.1 - 3.2e-163 530.3 0.0 5.3e-19 68.1 0.0 9.2 9 0 0 9 9 9 9 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM66145.1 - 6.6e-108 353.5 0.5 4.7e-12 46.3 0.0 9.3 9 0 0 9 9 9 9 Immunoglobulin domain Ig_2 PF13895.6 KFM66145.1 - 7e-70 231.4 1.0 4.4e-09 36.5 0.0 9.3 9 0 0 9 9 9 9 Immunoglobulin domain ig PF00047.25 KFM66145.1 - 3.7e-65 216.1 0.7 3.4e-08 33.6 0.0 9.4 9 0 0 9 9 9 9 Immunoglobulin domain Pkinase PF00069.25 KFM66145.1 - 3.7e-39 134.7 0.0 5.2e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 KFM66145.1 - 2.4e-38 130.7 4.0 0.0013 18.9 0.0 13.9 9 5 0 9 9 9 9 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 KFM66145.1 - 2.6e-24 85.9 0.0 3.9e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.12 KFM66145.1 - 2.5e-15 56.3 1.7 1.2 9.2 0.0 8.3 8 0 0 8 8 8 4 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 KFM66145.1 - 1.1e-10 41.4 0.0 0.36 10.9 0.0 8.5 9 2 0 9 9 9 2 Penicillin-Binding Protein C-terminus Family C1-set PF07654.15 KFM66145.1 - 1.3e-10 41.5 0.2 3.7 8.0 0.0 7.9 8 0 0 8 8 8 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFM66145.1 - 1.5e-10 40.5 0.1 0.018 14.6 0.0 6.2 7 0 0 7 7 7 2 Immunoglobulin domain Receptor_2B4 PF11465.8 KFM66145.1 - 3.9e-10 39.9 0.0 0.079 13.2 0.0 6.8 8 1 0 8 8 8 2 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFM66145.1 - 1.5e-07 31.4 1.2 3.9 7.6 0.0 7.4 9 0 0 9 9 7 1 Izumo-like Immunoglobulin domain fn3 PF00041.21 KFM66145.1 - 5.2e-07 29.9 0.0 1.7e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain V-set_CD47 PF08204.11 KFM66145.1 - 3.2e-06 27.1 0.0 0.97 9.4 0.0 5.2 6 0 0 6 6 6 2 CD47 immunoglobulin-like domain Ig_C17orf99 PF17736.1 KFM66145.1 - 0.00027 20.9 0.0 21 5.2 0.0 5.4 5 0 0 5 5 4 0 C17orf99 Ig domain C2-set PF05790.15 KFM66145.1 - 0.00071 19.7 0.1 9.9 6.4 0.0 4.9 5 0 0 5 5 5 0 Immunoglobulin C2-set domain DUF4099 PF13351.6 KFM66145.1 - 0.003 17.8 0.0 6.8 7.0 0.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4099) DUF11 PF01345.18 KFM66145.1 - 0.0095 16.2 0.0 5.1 7.5 0.0 4.3 3 1 0 3 3 3 1 Domain of unknown function DUF11 Herpes_gE PF02480.16 KFM66145.1 - 0.11 11.3 0.0 48 2.5 0.0 3.7 3 1 0 4 4 4 0 Alphaherpesvirus glycoprotein E Tissue_fac PF01108.17 KFM66145.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Tissue factor ACAS_N PF16177.5 KFM66145.1 - 0.35 10.8 3.0 14 5.7 0.0 4.7 7 0 0 7 7 7 0 Acetyl-coenzyme A synthetase N-terminus DcuA_DcuB PF03605.14 KFM66146.1 - 0.0066 15.4 0.4 0.009 14.9 0.4 1.2 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter DUF2834 PF11196.8 KFM66146.1 - 0.067 13.5 2.0 0.11 12.9 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2834) Acyl_transf_3 PF01757.22 KFM66146.1 - 0.14 11.2 7.4 0.16 11.0 7.4 1.1 1 0 0 1 1 1 0 Acyltransferase family UCMA PF17085.5 KFM66149.1 - 0.0083 16.1 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 Unique cartilage matrix associated protein ETRAMP PF09716.10 KFM66149.1 - 0.27 11.3 3.7 18 5.5 2.0 2.8 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Glutaminase PF04960.15 KFM66150.1 - 3e-60 203.9 0.4 3.7e-60 203.6 0.4 1.1 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.7 KFM66150.1 - 3.1e-13 50.1 0.0 5.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM66150.1 - 1.2e-08 35.3 0.0 7.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM66150.1 - 1.5e-07 31.6 0.0 6.9e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM66150.1 - 4.5e-07 30.0 0.0 1.1e-05 25.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KFM66150.1 - 8.1e-07 28.9 0.0 6.6e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Glutaminase PF04960.15 KFM66151.1 - 2.5e-14 53.1 0.1 2.7e-14 53.1 0.1 1.0 1 0 0 1 1 1 1 Glutaminase CRISPR_Cas9_WED PF18061.1 KFM66152.1 - 0.03 14.4 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain Acyl_transf_3 PF01757.22 KFM66153.1 - 4.3e-15 55.6 34.2 4.3e-15 55.6 34.2 1.5 2 0 0 2 2 2 1 Acyltransferase family T3SSipB PF16535.5 KFM66154.1 - 0.00021 21.8 19.1 0.023 15.2 2.7 3.0 1 1 2 3 3 3 2 Type III cell invasion protein SipB Fib_alpha PF08702.10 KFM66154.1 - 0.00071 19.8 18.9 0.0091 16.2 10.3 2.6 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KFM66154.1 - 0.00071 19.9 13.1 0.016 15.6 1.8 3.4 2 1 1 3 3 3 2 Flagella accessory protein C (FlaC) GAS PF13851.6 KFM66154.1 - 0.0016 17.9 28.6 0.017 14.5 13.9 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KFM66154.1 - 0.003 17.8 23.3 0.021 15.1 11.4 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF724 PF05266.14 KFM66154.1 - 0.0037 17.1 9.1 0.0037 17.1 9.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF724) LYTB PF02401.18 KFM66154.1 - 0.006 15.9 1.7 0.0082 15.4 0.7 1.5 1 1 1 2 2 2 1 LytB protein Tropomyosin_1 PF12718.7 KFM66154.1 - 0.007 16.5 26.6 0.021 15.0 8.9 2.8 1 1 2 3 3 3 2 Tropomyosin like SOGA PF11365.8 KFM66154.1 - 0.012 16.7 14.4 0.022 15.8 5.2 2.6 1 1 2 3 3 3 0 Protein SOGA EHN PF06441.12 KFM66154.1 - 0.012 15.9 4.9 0.082 13.3 0.6 2.4 2 1 0 2 2 2 0 Epoxide hydrolase N terminus MscS_porin PF12795.7 KFM66154.1 - 0.023 14.3 20.2 0.035 13.7 7.5 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain TRAF_BIRC3_bd PF16673.5 KFM66154.1 - 0.034 14.0 1.5 0.034 14.0 1.5 2.8 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain HrpB7 PF09486.10 KFM66154.1 - 0.037 14.4 16.6 1.5 9.2 3.3 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF641 PF04859.12 KFM66154.1 - 0.07 13.5 20.8 1.1 9.7 1.4 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) FliJ PF02050.16 KFM66154.1 - 0.082 13.1 22.9 2.3 8.5 7.5 3.2 1 1 1 2 2 2 0 Flagellar FliJ protein TMF_TATA_bd PF12325.8 KFM66154.1 - 0.09 13.0 23.3 0.49 10.6 9.2 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HMMR_N PF15905.5 KFM66154.1 - 0.12 11.8 25.3 0.68 9.4 25.3 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF5631 PF18645.1 KFM66154.1 - 0.17 12.3 2.4 5.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5631) BRE1 PF08647.11 KFM66154.1 - 0.18 11.9 29.0 2.8 8.1 7.0 3.3 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Lebercilin PF15619.6 KFM66154.1 - 0.18 11.5 27.7 0.32 10.6 3.6 2.9 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HIP1_clath_bdg PF16515.5 KFM66154.1 - 0.2 12.3 22.9 0.56 10.8 2.7 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaxin-6_N PF09177.11 KFM66154.1 - 0.21 12.2 14.3 2.3 8.8 1.2 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Spc7 PF08317.11 KFM66154.1 - 0.32 9.8 26.6 0.37 9.6 11.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin PF00261.20 KFM66154.1 - 0.33 10.3 25.8 0.069 12.5 8.0 2.2 1 1 0 2 2 2 0 Tropomyosin DUF5082 PF16888.5 KFM66154.1 - 0.34 11.2 18.3 1.2 9.4 3.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) PspA_IM30 PF04012.12 KFM66154.1 - 0.35 10.4 24.2 0.33 10.5 5.9 2.5 1 1 2 3 3 3 0 PspA/IM30 family CENP-F_leu_zip PF10473.9 KFM66154.1 - 0.38 10.8 24.7 1.6 8.8 9.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 KFM66154.1 - 0.38 10.8 11.2 1.5 9.0 1.7 3.3 3 0 0 3 3 3 0 TolA binding protein trimerisation Fez1 PF06818.15 KFM66154.1 - 0.46 10.9 22.6 1.9 8.9 12.0 2.3 1 1 1 2 2 2 0 Fez1 DUF4201 PF13870.6 KFM66154.1 - 0.53 10.0 29.2 1.1 9.0 5.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF4200 PF13863.6 KFM66154.1 - 0.54 10.7 27.6 0.91 9.9 11.9 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) KASH_CCD PF14662.6 KFM66154.1 - 0.86 9.4 26.0 3.5 7.4 13.7 2.6 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 KFM66154.1 - 0.88 10.2 15.8 3 8.5 3.1 3.4 2 1 1 3 3 3 0 SlyX WEMBL PF05701.11 KFM66154.1 - 0.91 8.1 25.8 0.31 9.7 9.2 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF4559 PF15112.6 KFM66154.1 - 1 9.0 15.5 1.4 8.6 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Csm1_N PF18504.1 KFM66154.1 - 1.2 9.5 19.9 1.1 9.6 3.0 3.8 1 1 1 3 3 3 0 Csm1 N-terminal domain GrpE PF01025.19 KFM66154.1 - 1.2 8.7 21.6 1.1 8.9 2.1 3.1 1 1 1 3 3 3 0 GrpE TMF_DNA_bd PF12329.8 KFM66154.1 - 1.3 9.1 25.3 0.48 10.4 5.9 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 KFM66154.1 - 1.3 9.0 21.8 0.6 10.1 4.3 3.2 2 1 0 3 3 3 0 Prefoldin subunit ERM PF00769.19 KFM66154.1 - 2 8.2 31.2 0.81 9.5 22.1 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family APG6_N PF17675.1 KFM66154.1 - 2.1 8.9 27.0 0.9 10.1 10.7 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region BST2 PF16716.5 KFM66154.1 - 2.3 8.9 20.7 8.9 7.0 1.2 3.1 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 YkyA PF10368.9 KFM66154.1 - 2.3 7.9 24.7 4.3 7.0 8.3 2.3 1 1 0 2 2 2 0 Putative cell-wall binding lipoprotein LMBR1 PF04791.16 KFM66154.1 - 3.3 6.5 14.0 4 6.2 14.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein KELK PF15796.5 KFM66154.1 - 3.3 8.2 26.1 1.3 9.5 5.9 2.7 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ADIP PF11559.8 KFM66154.1 - 4 7.5 23.9 8.3 6.5 7.1 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 KFM66154.1 - 4.4 7.4 21.5 1.7 8.8 8.6 2.2 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF745 PF05335.13 KFM66154.1 - 4.5 6.9 18.3 3.4 7.4 1.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF3584 PF12128.8 KFM66154.1 - 5.1 4.5 24.0 0.51 7.8 8.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 KFM66154.1 - 5.4 6.3 19.0 5.4 6.3 4.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 KFM66154.1 - 5.5 7.3 11.3 3.3 8.0 0.9 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 KFM66154.1 - 6 7.0 29.2 1.2 9.3 4.5 3.6 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 KFM66154.1 - 6.2 6.9 22.6 17 5.4 10.5 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2203 PF09969.9 KFM66154.1 - 7.5 7.3 14.2 5.3 7.8 3.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Exonuc_VII_L PF02601.15 KFM66154.1 - 7.6 6.0 20.1 29 4.1 20.1 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 KFM66154.1 - 8.3 5.7 22.1 30 3.8 22.0 1.9 1 1 0 1 1 1 0 FAM76 protein SOGA PF11365.8 KFM66155.1 - 4.6e-13 50.1 38.2 1.3e-07 32.6 6.1 15.7 5 3 9 15 15 15 6 Protein SOGA TPR_MLP1_2 PF07926.12 KFM66155.1 - 0.0024 17.9 49.5 0.0032 17.5 18.4 17.0 7 5 8 17 17 17 7 TPR/MLP1/MLP2-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM66156.1 - 2.7e-16 59.5 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66156.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66156.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66156.1 - 0.0023 17.6 0.6 0.0068 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66156.1 - 1.8 9.2 15.7 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66157.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66157.1 - 1.4e-13 50.8 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 KFM66159.1 - 1.1e-16 61.1 0.0 2.2e-16 60.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_C PF00433.24 KFM66159.1 - 1.3e-08 35.4 2.2 2.5e-08 34.5 2.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_Tyr PF07714.17 KFM66159.1 - 2.7e-05 23.6 0.0 3.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM66159.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF1512 PF07431.12 KFM66160.1 - 0.18 10.7 0.0 0.21 10.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) RVT_1 PF00078.27 KFM66161.1 - 0.012 15.1 0.1 0.014 15.0 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PEHE PF15275.6 KFM66162.1 - 2.7e-21 76.6 5.5 2.7e-21 76.6 5.5 3.9 2 1 0 2 2 2 1 PEHE domain MSL1_dimer PF16801.5 KFM66162.1 - 0.41 10.4 3.4 0.81 9.5 3.4 1.5 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Iron_traffic PF04362.14 KFM66165.1 - 0.17 11.6 9.2 0.86 9.3 1.8 2.7 1 1 1 2 2 2 0 Bacterial Fe(2+) trafficking RsgA_N PF16745.5 KFM66168.1 - 0.064 13.0 0.2 0.081 12.7 0.2 1.2 1 0 0 1 1 1 0 RsgA N-terminal domain FLYWCH PF04500.16 KFM66169.1 - 4.6e-15 55.5 1.3 7e-15 54.9 1.3 1.3 1 0 0 1 1 1 1 FLYWCH zinc finger domain Creatinase_N_2 PF16189.5 KFM66170.1 - 0.00016 21.8 0.0 0.00018 21.6 0.0 1.1 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KFM66171.1 - 2e-22 79.0 0.1 3.1e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Peptidase_M24 PF00557.24 KFM66171.1 - 5.2e-18 65.5 0.0 6.6e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_transf_49 PF13896.6 KFM66172.1 - 5.4e-30 104.9 1.3 5.9e-20 71.9 0.2 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 KFM66172.1 - 3.4e-05 23.7 0.0 7.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 CDC50 PF03381.15 KFM66173.1 - 1.5e-94 316.6 0.0 1.9e-94 316.3 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CHAT PF12770.7 KFM66175.1 - 6.2e-58 196.5 0.0 1.8e-57 195.0 0.0 1.8 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.6 KFM66175.1 - 1.8e-24 85.8 20.0 1.9e-10 40.9 0.0 6.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFM66175.1 - 1.4e-13 49.8 11.6 2.2 8.6 0.1 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFM66175.1 - 1.2e-11 43.7 6.0 0.093 12.8 0.1 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM66175.1 - 1.5e-11 43.5 16.6 0.011 15.6 0.1 9.6 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM66175.1 - 4.7e-09 35.8 21.2 0.12 12.2 0.0 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM66175.1 - 2e-07 30.7 6.0 0.00011 21.7 0.2 2.8 3 0 0 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 KFM66175.1 - 1.7e-05 24.7 22.6 0.23 11.8 0.1 8.8 10 1 0 10 10 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM66175.1 - 4.8e-05 22.9 7.8 4.3 7.1 0.0 6.3 7 0 0 7 7 5 1 TPR repeat ANAPC5 PF12862.7 KFM66175.1 - 5.1e-05 23.3 2.1 0.43 10.7 0.1 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 5 SPO22 PF08631.10 KFM66175.1 - 0.0058 16.2 1.9 0.0058 16.2 1.9 2.9 4 0 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 KFM66175.1 - 0.028 15.2 14.8 84 4.4 0.1 8.7 9 1 1 10 10 8 0 Tetratricopeptide repeat PPR_2 PF13041.6 KFM66175.1 - 0.044 14.0 0.2 6.6 7.0 0.0 3.3 4 0 0 4 4 3 0 PPR repeat family TPR_19 PF14559.6 KFM66175.1 - 0.05 14.1 11.3 0.15 12.6 0.3 5.1 3 2 5 8 8 8 0 Tetratricopeptide repeat TPR_21 PF09976.9 KFM66175.1 - 0.08 12.6 3.1 2.2 7.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain PPR PF01535.20 KFM66175.1 - 0.11 12.8 2.1 7.3 7.1 0.1 4.3 3 1 0 3 3 3 0 PPR repeat TPR_17 PF13431.6 KFM66175.1 - 1.3 9.5 10.0 2.4 8.7 0.0 5.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM66175.1 - 2 9.2 4.6 1.7e+02 3.2 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Spaetzle PF16077.5 KFM66176.1 - 1.6e-24 86.2 3.0 3.1e-24 85.3 3.0 1.5 1 0 0 1 1 1 1 Spaetzle GalP_UDP_tr_C PF02744.17 KFM66176.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain DDE_3 PF13358.6 KFM66177.1 - 6.5e-13 48.7 0.0 1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66177.1 - 1.7e-12 47.4 3.3 6e-12 45.6 1.0 2.3 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM66177.1 - 0.0053 17.3 1.9 0.052 14.2 0.3 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66178.1 - 4e-16 59.0 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66178.1 - 1.2e-12 47.8 0.0 2.5e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66178.1 - 3.2e-07 30.0 0.2 7.7e-07 28.8 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66178.1 - 0.003 17.3 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66178.1 - 2.5 8.8 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain I-set PF07679.16 KFM66179.1 - 1.6e-10 40.9 0.0 7.6e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM66179.1 - 4.1e-10 40.1 0.0 0.00016 22.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM66179.1 - 1.8e-07 31.3 0.0 1.3e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFM66179.1 - 1.8e-07 31.2 0.0 0.012 15.7 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM66179.1 - 1.6e-05 25.1 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM66179.1 - 2.6e-05 24.2 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM66179.1 - 0.032 14.3 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM66182.1 - 2.6e-16 59.6 2.2 4.8e-16 58.8 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66182.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_11 PF08241.12 KFM66183.1 - 5.3e-16 59.0 0.0 8.8e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM66183.1 - 1.5e-14 54.2 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM66183.1 - 1.8e-11 44.6 0.0 3.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM66183.1 - 1.2e-09 38.8 0.0 1.8e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM66183.1 - 3.6e-08 33.3 0.0 4.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM66183.1 - 4e-06 26.3 0.0 5.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KFM66183.1 - 0.00034 20.5 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 KFM66183.1 - 0.0052 16.4 0.0 0.008 15.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW SPG48 PF14764.6 KFM66183.1 - 0.064 13.7 0.6 0.95 10.0 0.1 2.5 2 1 1 3 3 3 0 AP-5 complex subunit, vesicle trafficking TMEM151 PF14857.6 KFM66184.1 - 8.1e-38 130.4 0.0 9.6e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 TMEM151 family zf-HIT PF04438.16 KFM66185.1 - 0.03 14.2 0.5 0.03 14.2 0.5 2.0 2 0 0 2 2 2 0 HIT zinc finger EF-hand_1 PF00036.32 KFM66186.1 - 1.4e-12 46.2 2.7 2.5e-06 26.7 0.3 2.5 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM66186.1 - 5.3e-11 41.5 1.0 0.00016 21.3 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFM66186.1 - 1.4e-09 37.0 2.4 0.00019 20.7 0.2 2.5 2 1 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFM66186.1 - 3.7e-08 33.7 1.2 4.9e-07 30.1 1.2 2.0 1 1 0 1 1 1 1 EF-hand domain pair GPHH PF16905.5 KFM66186.1 - 0.04 13.7 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Transposase_1 PF01359.18 KFM66187.1 - 1.3e-27 95.4 0.7 2.9e-27 94.3 0.7 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM66187.1 - 3.4e-16 59.1 0.3 6.8e-16 58.1 0.3 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase M60-like_N PF17291.2 KFM66187.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases HTH_32 PF13565.6 KFM66187.1 - 0.035 14.7 0.0 0.13 12.9 0.0 2.1 2 1 0 2 2 2 0 Homeodomain-like domain Chitin_bind_4 PF00379.23 KFM66188.1 - 3.7e-08 33.8 9.0 2.5e-07 31.1 9.0 2.7 1 0 0 1 1 1 1 Insect cuticle protein Astacin PF01400.24 KFM66189.1 - 1.6e-53 181.2 0.0 1.8e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFM66189.1 - 0.00016 20.7 0.2 0.00021 20.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 KFM66189.1 - 0.011 15.6 0.4 0.039 13.8 0.4 1.8 1 1 1 2 2 2 0 Matrixin Reprolysin_3 PF13582.6 KFM66189.1 - 0.041 14.4 0.1 0.067 13.7 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 KFM66189.1 - 0.091 11.3 0.1 0.13 10.9 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase family DUF4371 PF14291.6 KFM66192.1 - 4.7e-10 39.5 0.0 1.3e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM66192.1 - 0.0066 16.2 0.3 0.025 14.3 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4371 PF14291.6 KFM66195.1 - 8.1e-10 38.7 0.0 2.4e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM66195.1 - 0.0033 17.0 0.4 0.0033 17.0 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger C2H2-type HTH_Tnp_Tc3_2 PF01498.18 KFM66196.1 - 7.8e-16 58.1 6.5 1.7e-15 57.0 6.5 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66196.1 - 8.1e-16 58.1 0.1 8.5e-15 54.8 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM66196.1 - 0.00084 19.9 1.5 0.00084 19.9 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM66196.1 - 0.0074 16.1 1.9 0.13 12.1 0.0 3.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66196.1 - 0.017 15.2 0.1 0.074 13.2 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM66196.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.5 3 0 0 3 3 3 0 Winged helix-turn helix Ets PF00178.22 KFM66197.1 - 2.1e-33 114.6 0.7 4.5e-33 113.6 0.7 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFM66197.1 - 1.9e-15 56.6 0.0 4e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SUIM_assoc PF16619.5 KFM66197.1 - 0.0034 17.4 10.5 0.013 15.5 10.5 2.0 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KFM66197.1 - 0.0038 16.9 8.5 0.0054 16.4 8.5 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 KFM66197.1 - 0.015 14.3 8.5 0.023 13.7 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med15 PF09606.10 KFM66197.1 - 4.2 5.9 19.9 0.24 10.0 9.7 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Iso_dh PF00180.20 KFM66198.1 - 3.7e-105 351.9 0.0 4.3e-105 351.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NDK PF00334.19 KFM66199.1 - 8.1e-29 100.4 0.0 1.3e-26 93.2 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase LAGLIDADG_3 PF14528.6 KFM66200.1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 LAGLIDADG-like domain DUF1126 PF06565.12 KFM66200.1 - 0.013 15.4 0.0 0.052 13.4 0.0 1.8 1 1 0 1 1 1 0 DUF1126 PH-like domain Glyco_hydro_130 PF04041.13 KFM66200.1 - 0.094 11.6 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase zf-C2H2 PF00096.26 KFM66201.1 - 3.7e-05 23.9 1.8 7.8e-05 22.9 1.8 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66201.1 - 0.019 15.7 1.6 0.044 14.6 1.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM66201.1 - 0.93 10.0 8.5 6.9 7.3 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Potass_KdpF PF09604.10 KFM66204.1 - 4.2 7.5 4.5 6.9 6.8 4.5 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) HTH_Tnp_Tc3_2 PF01498.18 KFM66205.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66205.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SARA PF11409.8 KFM66206.1 - 0.073 13.3 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) Neogenin_C PF06583.12 KFM66208.1 - 0.06 13.2 0.1 0.063 13.1 0.1 1.0 1 0 0 1 1 1 0 Neogenin C-terminus PKD_channel PF08016.12 KFM66209.1 - 7.4e-40 136.9 0.1 8e-40 136.8 0.1 1.0 1 0 0 1 1 1 1 Polycystin cation channel PKD_channel PF08016.12 KFM66210.1 - 1.4e-28 99.8 2.9 1.5e-28 99.7 2.9 1.0 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFM66210.1 - 1.4e-07 31.0 2.4 1.4e-07 31.0 2.4 1.0 1 0 0 1 1 1 1 Ion transport protein DUF1822 PF08852.11 KFM66210.1 - 0.017 14.2 0.0 0.021 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) EF-hand_1 PF00036.32 KFM66211.1 - 9.9e-09 34.1 2.7 0.00052 19.4 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM66211.1 - 7.6e-08 31.7 3.7 0.006 16.4 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFM66211.1 - 1.7e-06 28.4 1.7 1.7e-06 28.4 1.7 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM66211.1 - 6.1e-05 22.3 4.3 0.0013 18.1 0.0 3.2 3 0 0 3 3 3 1 EF hand Fer4_24 PF18109.1 KFM66211.1 - 0.00021 21.5 1.0 0.00032 20.9 0.1 1.8 2 0 0 2 2 2 1 Ferredoxin I 4Fe-4S cluster domain EF-hand_8 PF13833.6 KFM66211.1 - 0.00044 20.0 2.6 0.042 13.7 0.0 2.8 1 1 1 2 2 2 1 EF-hand domain pair MtrG PF04210.13 KFM66211.1 - 0.035 14.0 0.2 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Cauli_DNA-bind PF03310.13 KFM66211.1 - 0.077 13.1 1.4 0.28 11.3 0.2 2.3 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein SPARC_Ca_bdg PF10591.9 KFM66211.1 - 0.097 13.0 6.4 0.67 10.3 1.6 3.0 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region CbiA PF01656.23 KFM66211.1 - 0.23 11.5 1.1 0.39 10.8 1.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Baculo_PEP_C PF04513.12 KFM66211.1 - 0.36 10.8 6.0 0.15 12.1 0.9 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_10 PF14788.6 KFM66211.1 - 0.37 10.7 3.8 0.54 10.2 2.3 2.1 2 0 0 2 2 2 0 EF hand Syntaxin_2 PF14523.6 KFM66211.1 - 0.43 11.0 7.3 0.16 12.4 2.7 2.5 2 1 0 2 2 2 0 Syntaxin-like protein DUF932 PF06067.11 KFM66211.1 - 2.4 7.9 8.6 0.22 11.2 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF932) AAA_23 PF13476.6 KFM66211.1 - 9.3 6.7 13.9 19 5.6 5.0 2.1 1 1 1 2 2 2 0 AAA domain TMPIT PF07851.13 KFM66211.1 - 9.9 5.3 8.3 1.7 7.8 2.5 2.0 2 0 0 2 2 2 0 TMPIT-like protein AAA PF00004.29 KFM66213.1 - 6e-12 46.1 0.0 1.4e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM66213.1 - 9.4e-07 28.9 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFM66213.1 - 6.6e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KFM66213.1 - 3e-05 24.1 0.0 8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KFM66213.1 - 0.00014 21.8 0.0 0.0013 18.7 0.0 2.4 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 KFM66213.1 - 0.00026 21.3 0.0 0.0024 18.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM66213.1 - 0.00092 19.6 0.0 0.084 13.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KFM66213.1 - 0.0018 17.5 0.0 0.0052 16.0 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 KFM66213.1 - 0.0033 17.6 0.0 0.0086 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM66213.1 - 0.0091 16.5 0.0 0.032 14.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KFM66213.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KFM66213.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFM66213.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KFM66213.1 - 0.032 13.8 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM66213.1 - 0.063 13.5 0.0 0.17 12.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM66213.1 - 0.07 13.6 0.0 0.31 11.6 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 KFM66213.1 - 0.099 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFM66213.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 KFM66213.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.11 KFM66213.1 - 0.17 11.8 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cadherin_3 PF16184.5 KFM66217.1 - 0.00039 20.4 0.6 0.38 10.8 0.2 2.1 2 0 0 2 2 2 2 Cadherin-like Cadherin_3 PF16184.5 KFM66218.1 - 0.00075 19.5 2.1 0.3 11.1 0.1 2.1 2 0 0 2 2 2 2 Cadherin-like Cadherin_3 PF16184.5 KFM66219.1 - 1.2e-16 60.7 0.3 1e-11 44.8 0.0 2.1 2 0 0 2 2 2 2 Cadherin-like Cadherin_3 PF16184.5 KFM66220.1 - 7.7e-20 71.0 6.4 1.7e-16 60.2 0.3 3.0 3 0 0 3 3 3 3 Cadherin-like Cadherin_3 PF16184.5 KFM66221.1 - 6.7e-10 39.0 0.2 6.6e-09 35.8 0.1 1.9 2 0 0 2 2 2 1 Cadherin-like Cadherin_4 PF17803.1 KFM66221.1 - 0.093 13.4 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial cadherin-like domain Cadherin_3 PF16184.5 KFM66222.1 - 1.5e-15 57.1 0.8 7.2e-12 45.3 0.1 2.0 2 0 0 2 2 2 2 Cadherin-like DUF5436 PF17504.2 KFM66222.1 - 0.054 13.8 0.1 0.075 13.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5436) DUF2746 PF10874.8 KFM66222.1 - 0.11 13.0 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Cadherin_3 PF16184.5 KFM66223.1 - 8.8e-31 106.2 7.0 6.1e-23 80.9 0.9 2.3 2 0 0 2 2 2 2 Cadherin-like Calx-beta PF03160.14 KFM66223.1 - 0.00067 19.8 0.3 0.0039 17.3 0.0 2.2 1 1 1 2 2 2 1 Calx-beta domain Big_9 PF17963.1 KFM66223.1 - 0.039 14.7 2.9 2.6 8.8 0.3 2.8 2 1 0 2 2 2 0 Bacterial Ig domain Calx-beta PF03160.14 KFM66224.1 - 3.3e-35 120.3 1.6 3.6e-12 46.3 0.2 4.7 5 0 0 5 5 5 4 Calx-beta domain ATE_C PF04377.15 KFM66225.1 - 0.021 15.4 0.1 0.028 15.0 0.1 1.4 1 1 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus ATP1G1_PLM_MAT8 PF02038.16 KFM66225.1 - 1 8.9 3.0 0.66 9.5 0.2 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Bax1-I PF01027.20 KFM66226.1 - 1e-45 156.1 14.8 1.4e-45 155.6 14.8 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 RRM_1 PF00076.22 KFM66227.1 - 5.4e-17 61.4 0.0 1.1e-16 60.4 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM66227.1 - 0.00047 20.0 0.0 0.00072 19.4 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFM66227.1 - 0.001 19.0 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif DUF4523 PF15023.6 KFM66227.1 - 0.0096 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) RRM_7 PF16367.5 KFM66227.1 - 0.057 13.5 0.1 1.1 9.4 0.0 2.6 1 1 1 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM66227.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HTH_Tnp_Tc3_2 PF01498.18 KFM66229.1 - 2.1e-16 59.9 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66229.1 - 7.7e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66230.1 - 8.3e-16 58.0 6.5 1.4e-15 57.3 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66230.1 - 8.5e-08 32.1 0.0 4.7e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM66230.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.7 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM66230.1 - 0.0082 15.9 0.3 0.23 11.3 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM66230.1 - 0.063 13.3 2.4 0.067 13.2 0.3 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDE_Tnp_IS1595 PF12762.7 KFM66231.1 - 0.00012 22.2 0.0 0.00014 21.9 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.6 KFM66231.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 DDE superfamily endonuclease EGF PF00008.27 KFM66232.1 - 2.1e-05 24.7 2.3 2.1e-05 24.7 2.3 1.9 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 KFM66232.1 - 0.0028 18.2 1.6 0.0028 18.2 1.6 2.3 3 0 0 3 3 1 1 Human growth factor-like EGF Chordopox_A13L PF05961.11 KFM66232.1 - 0.0044 17.2 0.2 0.0083 16.3 0.2 1.4 1 0 0 1 1 1 1 Chordopoxvirus A13L protein DUF3180 PF11377.8 KFM66232.1 - 0.0046 17.1 0.1 0.1 12.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3180) DUF5385 PF17359.2 KFM66232.1 - 0.012 15.2 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Insulin_TMD PF17870.1 KFM66232.1 - 0.018 15.1 0.8 0.038 14.1 0.8 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 KFM66232.1 - 0.065 14.1 0.0 0.27 12.1 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 KFM66232.1 - 0.07 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protocadherin MLANA PF14991.6 KFM66232.1 - 0.093 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Sigma_reg_N PF13800.6 KFM66232.1 - 0.1 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SIT PF15330.6 KFM66232.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT RIFIN PF02009.16 KFM66232.1 - 0.76 9.6 1.9 1.1 9.1 1.9 1.1 1 0 0 1 1 1 0 Rifin DDE_Tnp_4 PF13359.6 KFM66234.1 - 1e-10 41.5 0.0 6.2e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease CTP_transf_1 PF01148.20 KFM66236.1 - 2.1e-32 113.0 4.5 2.1e-32 113.0 4.5 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family CHD5 PF04420.14 KFM66236.1 - 1 9.2 2.9 0.69 9.7 0.5 1.8 1 1 1 2 2 2 0 CHD5-like protein CTP_transf_1 PF01148.20 KFM66237.1 - 0.0035 17.2 0.8 0.0043 16.9 0.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family TPR_19 PF14559.6 KFM66238.1 - 7.5e-12 45.6 0.0 3e-08 34.1 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM66238.1 - 9.6e-11 41.8 0.7 3.5e-05 24.0 0.1 2.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM66238.1 - 6.1e-09 35.3 0.4 7.3e-05 22.6 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM66238.1 - 1e-07 32.2 0.0 0.25 12.3 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM66238.1 - 4.3e-07 29.5 0.2 0.0013 18.5 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM66238.1 - 1.3e-06 28.2 0.0 0.0061 16.7 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM66238.1 - 1.5e-06 27.8 0.1 0.0025 17.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM66238.1 - 1.9e-05 25.2 0.0 0.00029 21.4 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM66238.1 - 5.4e-05 23.3 0.6 0.0003 20.9 0.2 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM66238.1 - 0.00012 22.2 0.0 0.37 11.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM66238.1 - 0.00028 20.4 0.2 0.00035 20.0 0.2 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_4 PF07721.14 KFM66238.1 - 0.0014 19.1 0.2 0.0049 17.4 0.0 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM66238.1 - 0.036 13.9 0.1 0.036 13.9 0.1 2.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM66238.1 - 0.036 14.1 0.2 3.6 7.7 0.1 2.5 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KFM66238.1 - 0.11 13.2 0.0 63 4.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM66238.1 - 0.14 11.9 0.3 13 5.6 0.0 2.6 2 1 1 3 3 3 0 TPR repeat TPPII_N PF12583.8 KFM66238.1 - 0.32 11.6 1.3 2.8 8.5 0.1 2.1 1 1 1 2 2 2 0 Tripeptidyl peptidase II N terminal TPR_1 PF00515.28 KFM66240.1 - 4e-20 70.7 0.9 1.6e-11 43.5 0.1 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM66240.1 - 5.2e-18 63.6 0.3 2.5e-08 33.4 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM66240.1 - 1.8e-16 58.9 0.1 4.8e-07 29.5 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM66240.1 - 8e-15 54.3 1.6 1.9e-12 46.6 0.1 2.7 1 1 2 3 3 3 2 TPR repeat TPR_12 PF13424.6 KFM66240.1 - 1.4e-11 44.5 0.4 3.1e-10 40.2 0.4 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM66240.1 - 2.8e-11 43.0 1.4 7.2e-06 26.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM66240.1 - 4.5e-09 35.7 0.3 0.00015 21.6 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM66240.1 - 6.9e-08 32.9 0.5 8.3e-07 29.4 0.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM66240.1 - 8.8e-08 32.7 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM66240.1 - 1.3e-07 31.8 0.0 0.0011 19.6 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM66240.1 - 1e-06 29.0 0.9 0.0078 16.8 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM66240.1 - 7.9e-05 22.4 0.8 0.052 13.4 0.2 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM66240.1 - 9.4e-05 22.5 0.0 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM66240.1 - 0.00013 22.1 0.1 0.00018 21.7 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KFM66240.1 - 0.00036 20.3 0.1 0.0028 17.4 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain NARP1 PF12569.8 KFM66240.1 - 0.0014 17.6 0.3 0.0019 17.2 0.3 1.3 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 SPO22 PF08631.10 KFM66240.1 - 0.022 14.3 0.1 0.036 13.6 0.1 1.5 1 1 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Coatomer_E PF04733.14 KFM66240.1 - 0.036 13.5 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 Coatomer epsilon subunit SHNi-TPR PF10516.9 KFM66240.1 - 0.049 13.1 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 SHNi-TPR TPR_4 PF07721.14 KFM66240.1 - 0.051 14.2 0.0 0.13 13.0 0.0 1.7 2 0 0 2 2 1 0 Tetratricopeptide repeat Ac110_PIF PF07280.11 KFM66240.1 - 0.71 9.7 2.8 0.75 9.6 0.1 2.2 2 0 0 2 2 2 0 Per os infectivity factor AC110 CNOT11 PF10155.9 KFM66243.1 - 6.6e-52 174.9 6.8 6.6e-52 174.9 6.8 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 TrmB PF01978.19 KFM66244.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB YqeY PF09424.10 KFM66245.1 - 0.26 11.3 8.3 1.1 9.3 0.7 2.8 2 0 0 2 2 2 0 Yqey-like protein UCH PF00443.29 KFM66246.1 - 4e-18 65.9 0.6 5.2e-18 65.5 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM66246.1 - 0.013 15.1 0.2 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Bac_chlorC PF02043.17 KFM66246.1 - 0.064 13.3 0.6 0.064 13.3 0.6 2.2 2 1 1 3 3 3 0 Bacteriochlorophyll C binding protein HTH_Tnp_Tc5 PF03221.16 KFM66247.1 - 9.9e-05 22.3 0.0 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KFM66248.1 - 3.9e-20 71.5 2.0 6e-20 70.9 2.0 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM66248.1 - 1.3e-05 25.0 0.1 2.7e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Bindin PF02084.15 KFM66248.1 - 0.0035 17.6 4.2 0.052 13.8 0.4 2.1 2 0 0 2 2 2 2 Bindin DUF1388 PF07142.12 KFM66249.1 - 0.96 9.5 7.5 0.25 11.3 3.8 1.9 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) CEP170_C PF15308.6 KFM66250.1 - 0.0048 15.5 0.0 0.0056 15.3 0.0 1.0 1 0 0 1 1 1 1 CEP170 C-terminus ABC_tran PF00005.27 KFM66251.1 - 1.1e-48 165.2 0.0 3.1e-23 82.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KFM66251.1 - 2.5e-21 75.5 1.5 2.5e-21 75.5 1.5 4.0 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 KFM66251.1 - 7.6e-20 71.9 0.1 2e-05 24.6 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM66251.1 - 1.8e-09 37.4 0.4 0.091 12.2 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KFM66251.1 - 2.6e-08 34.2 0.0 0.013 15.7 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KFM66251.1 - 3.4e-07 29.9 0.0 0.006 16.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KFM66251.1 - 8.9e-07 29.5 0.0 0.13 12.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KFM66251.1 - 3.5e-06 27.1 0.0 0.052 13.6 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KFM66251.1 - 4.6e-06 27.0 0.0 0.063 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM66251.1 - 1.5e-05 25.3 0.1 0.11 12.7 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFM66251.1 - 1.6e-05 25.3 0.1 0.17 12.2 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.6 KFM66251.1 - 3.9e-05 23.5 11.6 0.0065 16.2 0.0 4.4 5 0 0 5 5 4 2 AAA ATPase domain AAA_23 PF13476.6 KFM66251.1 - 5.1e-05 23.9 1.3 0.0026 18.3 0.0 3.8 5 0 0 5 5 3 2 AAA domain RsgA_GTPase PF03193.16 KFM66251.1 - 6.1e-05 23.0 0.0 0.083 12.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 KFM66251.1 - 0.00016 21.7 0.0 0.82 9.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KFM66251.1 - 0.00039 20.2 0.0 0.18 11.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KFM66251.1 - 0.00045 20.6 0.0 0.18 12.2 0.0 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFM66251.1 - 0.00071 19.2 0.0 0.15 11.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 KFM66251.1 - 0.00085 19.4 0.3 0.19 11.8 0.0 3.1 3 1 0 3 3 2 1 Dynamin family RNA_helicase PF00910.22 KFM66251.1 - 0.0019 18.6 0.0 0.34 11.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_27 PF13514.6 KFM66251.1 - 0.0023 17.6 0.0 1.7 8.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KFM66251.1 - 0.003 17.5 0.9 1.1 9.2 0.0 2.7 2 1 0 2 2 2 1 NACHT domain Rad17 PF03215.15 KFM66251.1 - 0.0037 17.2 0.0 0.54 10.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 KFM66251.1 - 0.0042 16.3 0.0 1.4 8.0 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 KFM66251.1 - 0.0049 16.6 0.0 0.75 9.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFM66251.1 - 0.006 16.6 0.1 4.5 7.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KFM66251.1 - 0.008 15.9 0.3 7.4 6.3 0.0 3.3 2 1 1 3 3 3 0 IstB-like ATP binding protein MukB PF04310.12 KFM66251.1 - 0.013 15.4 0.1 1.8 8.3 0.0 2.8 3 0 0 3 3 2 0 MukB N-terminal AAA_17 PF13207.6 KFM66251.1 - 0.013 15.9 2.7 2.8 8.4 0.0 3.6 4 0 0 4 4 3 0 AAA domain MeaB PF03308.16 KFM66251.1 - 0.018 14.1 1.1 2.2 7.2 0.0 3.0 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KFM66251.1 - 0.019 14.9 0.6 0.63 10.0 0.0 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 KFM66251.1 - 0.021 15.0 4.7 0.45 10.6 0.0 4.2 4 1 0 4 4 4 0 Helicase HerA, central domain DUF2813 PF11398.8 KFM66251.1 - 0.028 13.7 0.0 3.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) SRP54 PF00448.22 KFM66251.1 - 0.033 13.8 0.0 7.3 6.2 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arf PF00025.21 KFM66251.1 - 0.042 13.3 0.3 7.9 5.9 0.0 2.9 2 1 1 3 3 3 0 ADP-ribosylation factor family Roc PF08477.13 KFM66251.1 - 0.055 13.7 0.0 2.9 8.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 KFM66251.1 - 0.06 13.3 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SbcCD_C PF13558.6 KFM66251.1 - 0.064 13.5 0.1 2 8.7 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 KFM66251.1 - 0.072 12.7 0.1 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KFM66251.1 - 0.086 12.6 0.0 21 4.8 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IMP_cyclohyd PF07826.11 KFM66251.1 - 0.11 12.1 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein UCH PF00443.29 KFM66252.1 - 6.4e-05 22.6 0.6 7.4e-05 22.4 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM66252.1 - 0.00035 20.3 0.6 0.00041 20.0 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KFM66253.1 - 3.7e-17 62.7 0.1 4e-17 62.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM66253.1 - 5.3e-07 29.5 0.0 5.9e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YukD PF08817.10 KFM66255.1 - 0.022 15.5 0.8 1.6 9.5 0.0 3.6 4 0 0 4 4 4 0 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 KFM66255.1 - 0.023 14.4 0.1 1.7 8.5 0.0 3.8 4 0 0 4 4 4 0 Ubiquitin family zf-C2H2_jaz PF12171.8 KFM66257.1 - 0.14 12.5 0.6 0.14 12.5 0.6 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding SRCR PF00530.18 KFM66258.1 - 6.8e-16 58.6 1.0 9.2e-16 58.2 1.0 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFM66258.1 - 0.00015 22.3 1.5 0.00022 21.7 1.5 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFM66258.1 - 0.0066 17.0 0.1 0.011 16.3 0.1 1.3 1 0 0 1 1 1 1 Hepsin, SRCR domain ALS2CR8 PF15299.6 KFM66259.1 - 1.8e-26 93.4 2.2 2e-26 93.3 2.2 1.0 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DHO_dh PF01180.21 KFM66260.1 - 1.7e-100 336.0 0.2 2.3e-100 335.6 0.2 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DUF3689 PF12463.8 KFM66261.1 - 9.8e-108 360.1 6.3 1.5e-107 359.6 6.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) XPG_N PF00752.17 KFM66262.1 - 6.7e-36 122.8 0.1 3.3e-35 120.6 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KFM66262.1 - 1.3e-31 108.8 0.1 3.3e-31 107.5 0.1 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KFM66262.1 - 5.3e-06 26.9 0.6 3.9e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 KFM66262.1 - 0.018 14.9 0.0 0.057 13.3 0.0 1.8 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Pox_MCEL PF03291.16 KFM66263.1 - 9e-100 334.0 0.4 1.1e-99 333.8 0.4 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KFM66263.1 - 7.2e-13 49.1 0.2 2.6e-12 47.3 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM66263.1 - 2.4e-11 44.1 0.0 6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM66263.1 - 2.3e-09 37.9 0.0 8.4e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM66263.1 - 1.5e-07 31.3 0.0 3.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM66263.1 - 2.6e-07 30.6 0.0 4.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KFM66263.1 - 6.9e-05 22.2 0.0 0.00034 19.9 0.0 2.0 3 0 0 3 3 3 1 NNMT/PNMT/TEMT family CheR PF01739.18 KFM66263.1 - 0.037 13.5 0.3 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain zf-H2C2_2 PF13465.6 KFM66265.1 - 3.5e-21 74.6 19.5 3.6e-09 36.6 0.9 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66265.1 - 3.3e-14 52.5 29.4 1.8e-05 24.9 3.2 3.4 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66265.1 - 6.9e-11 42.0 25.1 0.0011 19.6 3.0 3.6 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM66265.1 - 9.8e-06 25.8 24.3 0.026 14.9 1.6 3.7 4 0 0 4 4 3 3 Zinc-finger of C2H2 type C1_4 PF07975.12 KFM66265.1 - 1.9e-05 24.8 12.8 0.0023 18.1 1.4 3.0 1 1 0 2 2 2 2 TFIIH C1-like domain zf-C2H2_6 PF13912.6 KFM66265.1 - 0.0005 20.0 32.4 0.0054 16.7 4.1 3.7 4 1 0 4 4 3 3 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM66265.1 - 0.00067 19.7 7.5 0.8 9.8 0.3 3.2 2 1 1 3 3 3 2 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.10 KFM66265.1 - 0.00094 19.2 4.4 0.15 12.2 1.3 2.8 2 1 1 3 3 3 2 Zinc ribbon domain zf-Di19 PF05605.12 KFM66265.1 - 0.0018 18.5 9.4 0.057 13.7 1.3 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KFM66265.1 - 0.0087 16.7 9.2 0.27 11.9 0.4 3.0 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats Elf1 PF05129.13 KFM66265.1 - 0.017 15.2 7.6 0.26 11.4 1.7 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF3268 PF11672.8 KFM66265.1 - 0.039 14.3 2.7 1.6 9.1 0.5 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain HypA PF01155.19 KFM66265.1 - 0.049 13.7 4.2 0.84 9.7 4.2 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 KFM66265.1 - 0.056 13.1 6.1 0.67 9.6 0.3 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 KFM66265.1 - 0.056 13.6 11.3 8.2 6.7 1.2 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger Zf_RING PF16744.5 KFM66265.1 - 0.17 12.0 8.3 2.8 8.1 0.3 3.0 1 1 2 3 3 3 0 KIAA1045 RING finger zf-C2H2_jaz PF12171.8 KFM66265.1 - 0.19 12.0 21.5 0.89 9.9 0.2 4.1 3 2 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PHD PF00628.29 KFM66265.1 - 0.31 11.0 7.1 0.98 9.4 3.4 2.3 2 0 0 2 2 2 0 PHD-finger zf-CCHC_2 PF13696.6 KFM66265.1 - 0.48 10.3 0.2 0.48 10.3 0.2 3.6 4 0 0 4 4 3 0 Zinc knuckle UBZ_FAAP20 PF15750.5 KFM66265.1 - 0.68 9.9 5.5 7.9 6.5 0.2 3.1 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger DUF2256 PF10013.9 KFM66265.1 - 0.74 10.0 6.0 15 5.8 0.2 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 KFM66265.1 - 1.5 9.4 19.3 0.26 11.8 0.9 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.21 KFM66265.1 - 1.6 9.0 14.4 9.3 6.5 0.6 2.9 1 1 1 2 2 2 0 FYVE zinc finger zf-C2HC_2 PF13913.6 KFM66265.1 - 2.8 7.9 9.0 36 4.4 0.2 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type TFIIS_C PF01096.18 KFM66265.1 - 3.1 7.7 7.9 14 5.7 0.6 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Vps39_2 PF10367.9 KFM66265.1 - 5.8 7.4 11.1 17 5.9 0.5 3.1 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 DDE_3 PF13358.6 KFM66266.1 - 0.00035 20.3 0.1 0.00048 19.9 0.1 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.14 KFM66267.1 - 0.027 14.2 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region zf-H2C2_2 PF13465.6 KFM66268.1 - 2.6e-21 75.0 19.3 1.5e-09 37.8 0.6 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66268.1 - 9.3e-18 63.6 20.6 2.3e-06 27.7 1.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66268.1 - 9.5e-14 50.9 18.1 0.00017 22.1 1.0 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM66268.1 - 5.9e-10 38.9 19.4 0.00014 21.8 1.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM66268.1 - 2.2e-09 37.4 16.0 0.0075 16.6 0.5 3.7 3 1 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM66268.1 - 0.0002 21.6 16.2 0.095 13.0 0.3 3.9 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM66268.1 - 0.0012 18.9 4.5 0.53 10.4 0.1 3.1 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.10 KFM66268.1 - 0.0015 18.6 4.6 0.13 12.4 2.1 2.8 2 1 1 3 3 3 1 Zinc ribbon domain C1_4 PF07975.12 KFM66268.1 - 0.0036 17.5 7.9 0.017 15.3 1.4 2.6 1 1 2 3 3 3 1 TFIIH C1-like domain zf-AN1 PF01428.16 KFM66268.1 - 0.0066 16.6 6.0 5.7 7.2 0.1 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger zf_C2H2_ZHX PF18387.1 KFM66268.1 - 0.0067 16.0 9.3 0.064 12.9 2.7 2.9 1 1 2 3 3 3 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_8 PF15909.5 KFM66268.1 - 0.0077 16.5 7.2 0.086 13.1 2.4 2.1 1 1 1 2 2 2 2 C2H2-type zinc ribbon GAGA PF09237.11 KFM66268.1 - 0.011 15.6 3.5 0.38 10.6 0.1 2.6 1 1 2 3 3 3 0 GAGA factor zf-LYAR PF08790.11 KFM66268.1 - 0.013 15.4 7.0 5.6 7.0 0.1 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFM66268.1 - 0.015 14.8 3.9 5.5 6.7 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 KFM66268.1 - 0.056 13.5 4.4 0.066 13.3 1.0 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.12 KFM66268.1 - 0.058 13.4 6.0 24 5.0 6.2 2.7 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_2 PF12756.7 KFM66268.1 - 0.058 13.7 10.0 2.1 8.7 0.8 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM66268.1 - 0.06 13.5 4.3 15 5.8 0.2 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.19 KFM66268.1 - 0.069 13.2 2.9 0.23 11.5 2.9 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-MYST PF17772.1 KFM66268.1 - 0.1 12.2 6.7 0.91 9.2 0.0 3.0 2 1 1 3 3 3 0 MYST family zinc finger domain Zf_RING PF16744.5 KFM66268.1 - 0.16 12.1 7.2 23 5.2 3.6 3.0 1 1 2 3 3 3 0 KIAA1045 RING finger zf-Dof PF02701.15 KFM66268.1 - 0.17 12.1 7.3 2.9 8.1 0.1 2.9 1 1 2 3 3 3 0 Dof domain, zinc finger UBZ_FAAP20 PF15750.5 KFM66268.1 - 0.28 11.1 4.1 9.1 6.3 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger FYVE PF01363.21 KFM66268.1 - 0.51 10.5 11.3 10 6.4 0.5 2.8 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KFM66268.1 - 0.59 10.0 11.5 7 6.5 1.0 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFM66268.1 - 0.59 10.8 6.8 3.9 8.2 1.1 2.9 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Vps39_2 PF10367.9 KFM66268.1 - 0.83 10.1 9.5 8.5 6.9 0.4 3.1 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 PriA_CRR PF18319.1 KFM66268.1 - 0.84 9.7 10.5 0.21 11.6 1.1 3.0 3 1 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf-DBF PF07535.12 KFM66268.1 - 0.93 9.7 7.0 0.49 10.6 0.9 2.9 3 0 0 3 3 3 0 DBF zinc finger zf-CCHC_2 PF13696.6 KFM66268.1 - 0.98 9.3 0.1 0.98 9.3 0.1 3.5 4 0 0 4 4 3 0 Zinc knuckle zf-C2HE PF16278.5 KFM66268.1 - 1 9.9 16.5 1.3 9.5 0.4 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger HNH PF01844.23 KFM66268.1 - 1.5 9.1 7.1 12 6.2 0.2 3.1 3 0 0 3 3 3 0 HNH endonuclease zf-C2HC_2 PF13913.6 KFM66268.1 - 4.1 7.4 11.5 18 5.4 0.2 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type TFIIS_C PF01096.18 KFM66268.1 - 4.8 7.1 8.6 11 6.0 0.4 3.0 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-C2H2 PF00096.26 KFM66269.1 - 3e-17 62.0 21.5 1.2e-06 28.6 0.7 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66269.1 - 1.4e-13 50.4 21.2 0.00035 21.2 3.4 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM66269.1 - 9.8e-12 44.7 24.8 8e-07 29.2 2.9 4.3 4 1 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 KFM66269.1 - 2.9e-10 40.2 22.0 0.0002 21.6 4.4 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM66269.1 - 3.4e-05 24.0 17.3 0.077 13.3 2.4 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding FYVE PF01363.21 KFM66269.1 - 0.00044 20.3 15.5 0.0011 19.0 7.2 2.1 2 0 0 2 2 2 1 FYVE zinc finger zf-MYST PF17772.1 KFM66269.1 - 0.00065 19.3 12.3 0.29 10.8 1.9 3.1 1 1 2 3 3 3 2 MYST family zinc finger domain zf-C2H2_6 PF13912.6 KFM66269.1 - 0.0026 17.7 23.8 0.56 10.3 0.4 4.4 3 1 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFM66269.1 - 0.0048 17.2 17.5 0.023 15.0 8.2 3.0 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-B_box PF00643.24 KFM66269.1 - 0.0073 16.4 2.4 0.0073 16.4 2.4 3.2 2 1 0 2 2 2 1 B-box zinc finger BolA PF01722.18 KFM66269.1 - 0.015 15.6 0.1 1.6 9.0 0.1 2.7 1 1 1 2 2 2 0 BolA-like protein GAGA PF09237.11 KFM66269.1 - 0.015 15.1 9.3 0.51 10.2 0.7 3.0 1 1 2 3 3 3 0 GAGA factor zf-RING_2 PF13639.6 KFM66269.1 - 0.018 15.4 6.2 0.018 15.4 6.2 2.8 1 1 2 3 3 3 0 Ring finger domain FYVE_2 PF02318.16 KFM66269.1 - 0.02 15.1 6.0 0.02 15.1 6.0 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger C1_4 PF07975.12 KFM66269.1 - 0.031 14.5 4.5 0.031 14.5 4.5 2.5 1 1 0 2 2 2 0 TFIIH C1-like domain Zf_RING PF16744.5 KFM66269.1 - 0.052 13.7 16.7 0.38 10.9 2.0 3.0 1 1 2 3 3 3 0 KIAA1045 RING finger zf-H2C2_5 PF13909.6 KFM66269.1 - 0.055 13.2 0.2 0.055 13.2 0.2 4.3 3 2 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.15 KFM66269.1 - 0.082 12.9 21.1 0.23 11.5 3.3 3.3 2 1 1 3 3 3 0 BED zinc finger Complex1_49kDa PF00346.19 KFM66269.1 - 0.17 11.0 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-C2H2_9 PF16293.5 KFM66269.1 - 0.42 10.5 10.7 2.4 8.1 0.3 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-RING_5 PF14634.6 KFM66269.1 - 0.42 10.6 17.9 0.088 12.8 6.5 2.9 1 1 2 3 3 3 0 zinc-RING finger domain zf-C2H2_11 PF16622.5 KFM66269.1 - 0.77 9.6 17.5 2.1 8.2 1.6 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 KFM66269.1 - 0.79 10.2 0.2 0.79 10.2 0.2 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-CCHC_2 PF13696.6 KFM66269.1 - 0.99 9.3 14.5 2.1 8.3 0.3 3.2 3 0 0 3 3 3 0 Zinc knuckle zf_UBZ PF18439.1 KFM66269.1 - 1 9.0 15.2 6.6 6.4 0.1 3.8 3 1 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Baculo_IE-1 PF05290.11 KFM66269.1 - 1.4 8.8 15.7 4.6 7.2 0.6 2.9 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C2HCIx2C PF10782.9 KFM66269.1 - 6.1 6.8 12.4 0.23 11.4 1.3 2.5 2 1 0 2 2 2 0 Zinc-finger HTH_Tnp_Tc3_2 PF01498.18 KFM66270.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66270.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66270.1 - 3.9e-06 26.5 0.8 1.9e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66270.1 - 0.04 13.7 0.3 0.12 12.2 0.3 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM66270.1 - 4 8.1 15.0 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain PmbA_TldD PF01523.16 KFM66271.1 - 0.034 14.0 0.0 0.037 13.9 0.0 1.0 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DENN PF02141.21 KFM66272.1 - 3.9e-07 30.2 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFM66272.1 - 4.2e-07 30.6 0.5 6.9e-07 29.9 0.5 1.4 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFM66274.1 - 2.2e-11 43.6 4.7 3.8e-11 42.8 3.6 2.0 2 0 0 2 2 2 1 dDENN domain N-SET PF11764.8 KFM66274.1 - 0.094 12.8 0.4 0.15 12.2 0.4 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N DDE_Tnp_1_7 PF13843.6 KFM66276.1 - 0.01 15.1 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 Ribosomal_L27 PF01016.19 KFM66277.1 - 3.9e-11 42.8 0.0 5.9e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Dimer_Tnp_hAT PF05699.14 KFM66278.1 - 8.3e-14 51.2 0.8 1.3e-13 50.5 0.8 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HJURP_mid PF12346.8 KFM66278.1 - 0.037 14.5 0.1 0.15 12.5 0.1 1.9 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat DBD_Tnp_Hermes PF10683.9 KFM66279.1 - 0.0051 16.5 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain Dimer_Tnp_hAT PF05699.14 KFM66280.1 - 2.1e-12 46.7 0.3 7e-12 45.0 0.3 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DBD_Tnp_Hermes PF10683.9 KFM66280.1 - 0.00044 19.9 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain DUF4413 PF14372.6 KFM66280.1 - 0.0015 18.8 2.1 0.0027 18.0 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4413) DUF3385 PF11865.8 KFM66280.1 - 0.014 15.4 1.9 0.15 11.9 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) zf-BED PF02892.15 KFM66280.1 - 1.6 8.9 11.9 2 8.5 1.5 3.9 2 2 0 2 2 2 0 BED zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM66281.1 - 2.1e-16 59.9 2.2 3.7e-16 59.1 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66281.1 - 3.8e-14 52.7 0.0 6.3e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66282.1 - 2.6e-16 59.6 2.8 5e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66282.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66282.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66282.1 - 0.0024 17.6 0.6 0.0068 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66282.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Homeodomain PF00046.29 KFM66283.1 - 2.4e-22 78.6 8.9 6.8e-22 77.1 8.9 1.8 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFM66283.1 - 0.21 11.9 0.1 0.33 11.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Neur_chan_memb PF02932.16 KFM66283.1 - 0.53 10.3 11.1 1.2 9.2 0.3 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KFM66283.1 - 9.6 4.8 11.1 2.9 6.6 8.0 1.6 2 0 0 2 2 2 0 Presenilin Peptidase_S9 PF00326.21 KFM66286.1 - 1.2e-65 220.9 0.0 1.4e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFM66286.1 - 0.0033 16.7 0.0 0.033 13.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KFM66286.1 - 0.018 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 KFM66286.1 - 0.055 13.0 0.0 0.074 12.6 0.0 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 KFM66286.1 - 0.096 12.6 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9_N PF02897.15 KFM66287.1 - 2e-132 441.9 0.0 2.2e-132 441.8 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain HTH_Tnp_Tc3_2 PF01498.18 KFM66291.1 - 1.6e-17 63.5 1.2 7.5e-16 58.1 2.2 2.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66291.1 - 1.9e-13 50.4 0.0 3.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66291.1 - 3.9e-07 29.7 1.6 8.8e-07 28.6 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66291.1 - 0.0035 17.1 0.5 0.0095 15.7 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66292.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66292.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66292.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66292.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66292.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Amino_oxidase PF01593.24 KFM66293.1 - 6.5e-20 71.8 0.0 6.5e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM66293.1 - 5.5e-14 52.2 0.0 7.7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM66293.1 - 3.3e-07 30.2 2.8 4.8e-07 29.7 2.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFM66293.1 - 5e-07 29.3 0.6 1.9e-06 27.4 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KFM66293.1 - 1.6e-06 27.5 1.3 2.4e-06 26.9 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFM66293.1 - 8.5e-06 25.2 0.7 1.2e-05 24.6 0.7 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KFM66293.1 - 8.5e-06 25.2 0.0 9.5e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM66293.1 - 1.5e-05 25.4 0.6 3e-05 24.5 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFM66293.1 - 6.1e-05 22.6 2.3 7.8e-05 22.2 1.7 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFM66293.1 - 6.5e-05 21.8 0.2 8.6e-05 21.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KFM66293.1 - 0.00014 21.2 0.2 0.00017 21.0 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 KFM66293.1 - 0.00086 18.2 0.0 0.00092 18.1 0.0 1.1 1 0 0 1 1 1 1 MCRA family GIDA PF01134.22 KFM66293.1 - 0.0013 17.9 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFM66293.1 - 0.0018 17.4 0.1 0.0026 16.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFM66293.1 - 0.0021 17.3 0.2 0.0049 16.2 0.2 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFM66293.1 - 0.0052 16.8 0.1 0.14 12.2 0.1 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KFM66293.1 - 0.034 14.0 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 KFM66293.1 - 0.034 12.6 0.1 0.042 12.3 0.1 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like IlvN PF07991.12 KFM66293.1 - 0.042 13.4 0.1 0.068 12.7 0.0 1.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KFM66293.1 - 0.12 12.6 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Prefoldin_3 PF13758.6 KFM66293.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit NAD_binding_9 PF13454.6 KFM66293.1 - 0.17 11.8 0.1 0.37 10.8 0.1 1.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.6 KFM66293.1 - 0.17 12.4 0.0 0.36 11.3 0.0 1.6 1 1 0 1 1 1 0 XdhC Rossmann domain Ig_3 PF13927.6 KFM66295.1 - 6.4e-20 71.5 1.5 1.9e-15 57.2 0.5 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM66295.1 - 5.3e-16 58.5 0.3 4.7e-10 39.4 0.1 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM66295.1 - 5.3e-15 55.5 1.5 1.2e-10 41.6 0.3 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM66295.1 - 5e-14 52.2 0.2 7.1e-10 38.9 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM66295.1 - 1.9e-07 31.2 1.8 0.1 12.8 0.1 3.1 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM66295.1 - 0.0027 17.2 0.0 0.29 10.7 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 KFM66295.1 - 0.0034 17.6 0.5 2 8.7 0.1 2.4 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM66295.1 - 0.074 13.1 0.0 2.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFM66296.1 - 1.4e-08 34.7 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM66296.1 - 3.7e-05 24.3 0.2 0.006 17.2 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM66296.1 - 0.00061 20.1 0.1 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM66296.1 - 0.00064 19.7 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFM66296.1 - 0.0026 17.9 0.0 0.073 13.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 KFM66296.1 - 0.0046 17.3 0.0 0.0095 16.3 0.0 1.5 2 0 0 2 2 2 1 Immunoglobulin C1-set domain HTH_Tnp_Tc3_2 PF01498.18 KFM66297.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66297.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66298.1 - 1.1e-16 60.8 1.9 4.1e-16 59.0 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66298.1 - 8.6e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 KFM66301.1 - 7.1e-08 32.2 0.0 7.6e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAN_1 PF00024.26 KFM66302.1 - 2.8e-27 94.5 20.4 8.2e-12 44.9 2.7 3.1 3 0 0 3 3 3 3 PAN domain V-ATPase_C PF03223.15 KFM66302.1 - 0.088 12.2 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit C OapA PF04225.12 KFM66304.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.0 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain Tim17 PF02466.19 KFM66306.1 - 3.7e-06 27.3 5.6 1.9e-05 25.0 5.6 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Arf PF00025.21 KFM66307.1 - 2.8e-78 261.3 0.1 3.2e-78 261.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFM66307.1 - 9.8e-15 54.8 0.1 1.3e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM66307.1 - 6e-14 52.0 0.0 6.7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFM66307.1 - 4.6e-13 49.0 0.7 6.5e-09 35.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFM66307.1 - 1.3e-12 47.5 0.0 1.6e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFM66307.1 - 5.7e-11 42.2 0.0 7.2e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM66307.1 - 8e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFM66307.1 - 0.012 14.9 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Paz_1 PF18349.1 KFM66307.1 - 0.019 14.9 0.0 0.26 11.3 0.0 2.1 1 1 1 2 2 2 0 PAZ domain SpoOE-like PF09388.10 KFM66307.1 - 0.047 13.6 1.2 0.081 12.8 1.2 1.3 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein MobB PF03205.14 KFM66307.1 - 0.099 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KFM66307.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF2754 PF10953.8 KFM66307.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) SoPB_HTH PF18090.1 KFM66307.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Centromere-binding protein HTH domain WW PF00397.26 KFM66308.1 - 0.0002 21.4 4.0 0.49 10.5 5.6 2.3 2 0 0 2 2 2 2 WW domain RhoGAP PF00620.27 KFM66310.1 - 7.2e-31 107.1 0.0 1.7e-30 105.8 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 KFM66310.1 - 7.9e-31 106.8 0.2 1.9e-29 102.3 0.0 3.1 4 0 0 4 4 4 1 MyTH4 domain HTH_Tnp_Tc3_2 PF01498.18 KFM66312.1 - 1.6e-13 50.7 0.9 3.4e-13 49.7 0.9 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66312.1 - 4.4e-06 26.5 0.0 3.5e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Crp_2 PF13545.6 KFM66312.1 - 0.0054 16.7 1.2 0.024 14.6 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_32 PF13565.6 KFM66312.1 - 0.027 15.1 1.8 0.027 15.1 1.8 2.6 1 1 1 2 2 2 0 Homeodomain-like domain MarR_2 PF12802.7 KFM66312.1 - 0.078 12.9 0.6 0.55 10.2 0.0 2.4 1 1 1 2 2 2 0 MarR family Reeler PF02014.16 KFM66313.1 - 9e-23 81.4 0.0 1.1e-22 81.2 0.0 1.1 1 0 0 1 1 1 1 Reeler domain HTH_Tnp_Tc3_2 PF01498.18 KFM66314.1 - 5.2e-14 52.3 1.6 1.1e-13 51.2 1.6 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66314.1 - 2.5e-10 40.3 0.0 4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM66314.1 - 0.01 16.4 2.6 0.01 16.4 2.6 2.3 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66315.1 - 2.7e-16 59.5 3.8 5.7e-16 58.5 2.2 2.3 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM66315.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66315.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66315.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66315.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66316.1 - 3.9e-16 59.1 3.4 5.2e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66316.1 - 2.8e-13 49.9 0.0 4.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66316.1 - 6.2e-08 32.3 0.8 6.5e-07 29.0 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66316.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66316.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66317.1 - 2.7e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66317.1 - 1.3e-13 51.0 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66317.1 - 4.4e-07 29.6 1.5 6.1e-07 29.1 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66317.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66317.1 - 1.6 9.4 15.7 0.1 13.2 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM66318.1 - 7.3e-23 81.4 0.9 8.4e-23 81.2 0.9 1.0 1 0 0 1 1 1 1 Transposase IS4 RSD-2 PF07547.13 KFM66318.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.4 1 1 0 1 1 1 0 RSD-2 N-terminal domain RVT_1 PF00078.27 KFM66319.1 - 4.4e-07 29.6 0.1 5.4e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 KFM66320.1 - 1.9e-31 106.8 60.1 2.1e-05 24.7 6.4 7.2 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM66320.1 - 5.9e-31 105.5 46.3 1.4e-06 28.5 3.7 7.4 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM66320.1 - 1.2e-18 66.2 55.9 0.0076 17.0 0.7 7.2 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 KFM66320.1 - 3.4e-18 65.4 38.6 0.0005 20.4 3.1 7.2 7 1 1 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM66320.1 - 2e-11 43.9 31.0 0.0037 17.5 0.1 7.3 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM66320.1 - 5.1e-08 32.7 41.1 0.063 13.3 2.1 7.2 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM66320.1 - 2.2e-05 24.2 14.3 5.3 7.0 0.1 6.0 3 2 3 6 6 6 1 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFM66320.1 - 0.00011 22.2 17.6 1.1 9.4 0.2 6.3 6 0 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_8 PF15909.5 KFM66320.1 - 0.0015 18.8 32.4 0.07 13.4 4.9 3.5 1 1 2 3 3 3 2 C2H2-type zinc ribbon BolA PF01722.18 KFM66320.1 - 0.008 16.4 12.0 2.9 8.2 0.5 5.4 1 1 4 5 5 5 1 BolA-like protein GAGA PF09237.11 KFM66320.1 - 0.02 14.7 17.4 0.042 13.6 0.0 5.1 3 1 4 7 7 7 0 GAGA factor zf-BED PF02892.15 KFM66320.1 - 0.031 14.3 38.1 4 7.6 0.7 6.4 1 1 3 5 5 5 0 BED zinc finger zf-C2HC_2 PF13913.6 KFM66320.1 - 0.032 14.1 26.8 0.045 13.7 0.3 5.7 6 0 0 6 6 6 0 zinc-finger of a C2HC-type XPA_N PF01286.18 KFM66320.1 - 0.22 11.6 23.2 6.2 7.0 0.1 6.6 7 0 0 7 7 7 0 XPA protein N-terminal LIM PF00412.22 KFM66320.1 - 0.22 11.7 27.1 0.15 12.3 0.9 5.3 3 2 2 5 5 5 0 LIM domain zf-C2H2_2 PF12756.7 KFM66320.1 - 0.39 11.1 31.9 7.5 6.9 8.4 5.5 1 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM66320.1 - 0.48 10.1 19.1 0.95 9.1 0.1 6.4 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM66320.1 - 0.54 10.4 25.1 0.7 10.1 0.1 5.4 5 2 0 5 5 5 0 Zinc ribbon domain zf-MYST PF17772.1 KFM66320.1 - 0.58 9.8 31.1 2.2 8.0 0.2 6.8 2 2 5 7 7 7 0 MYST family zinc finger domain HNH PF01844.23 KFM66320.1 - 0.74 10.0 24.5 12 6.1 0.3 6.2 6 0 0 6 6 6 0 HNH endonuclease zf-piccolo PF05715.13 KFM66320.1 - 1.5 9.0 18.6 6.5 7.0 2.7 4.5 4 1 1 5 5 5 0 Piccolo Zn-finger ADK_lid PF05191.14 KFM66320.1 - 2.6 8.1 28.7 2 8.5 3.5 5.4 4 1 1 5 5 5 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM66320.1 - 2.6 8.9 25.2 2.4 9.0 1.0 4.1 1 1 5 6 6 6 0 zinc-ribbon family zf-LYAR PF08790.11 KFM66320.1 - 4.7 7.2 27.9 10 6.1 0.5 7.1 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KFM66320.1 - 4.8 7.0 26.4 0.28 11.0 0.5 5.3 5 0 0 5 5 5 0 zinc-finger C2H2-type Vitellogenin_N PF01347.22 KFM66322.1 - 1.7e-20 73.0 0.2 2.1e-20 72.7 0.2 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region Vitellogenin_N PF01347.22 KFM66323.1 - 6.1e-11 41.4 1.3 2.2e-10 39.6 1.2 1.7 1 1 0 1 1 1 1 Lipoprotein amino terminal region TGF_beta PF00019.20 KFM66324.1 - 2.6e-30 105.4 1.2 5.2e-30 104.5 1.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFM66324.1 - 9e-07 28.9 3.7 9e-07 28.9 3.7 2.2 1 1 1 2 2 2 1 TGF-beta propeptide Myb_DNA-binding PF00249.31 KFM66325.1 - 4.1e-10 39.7 0.0 9.3e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KFM66325.1 - 4.2e-08 33.4 0.7 1.6e-07 31.5 0.0 2.3 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KFM66325.1 - 0.012 15.9 0.3 0.056 13.7 0.0 2.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain zf-UBR PF02207.20 KFM66325.1 - 0.028 14.6 1.7 0.065 13.4 1.7 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) AIF_C PF14721.6 KFM66326.1 - 1.4e-50 171.0 0.0 3e-50 170.0 0.0 1.6 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.14 KFM66326.1 - 6.7e-43 147.0 0.0 1e-42 146.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM66326.1 - 5.3e-11 42.9 0.0 6.2e-09 36.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM66326.1 - 6.2e-08 32.3 0.1 3.6e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM66326.1 - 7.7e-05 22.0 0.0 0.0081 15.3 0.0 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFM66326.1 - 0.00012 21.9 2.7 1.3 8.5 0.0 3.6 2 2 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KFM66326.1 - 0.00019 20.3 0.1 0.068 11.9 0.0 3.1 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_9 PF13454.6 KFM66326.1 - 0.0052 16.8 0.3 1.3 9.0 0.0 3.3 2 1 0 3 3 3 1 FAD-NAD(P)-binding DUF4417 PF14386.6 KFM66326.1 - 0.0087 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4417) Amino_oxidase PF01593.24 KFM66326.1 - 0.019 14.3 0.1 0.044 13.1 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KFM66326.1 - 0.1 11.6 3.3 6.1 5.8 0.0 3.2 2 1 1 3 3 3 0 Glucose inhibited division protein A WD40 PF00400.32 KFM66327.1 - 8.4e-23 80.2 5.6 1.2e-06 29.1 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM66327.1 - 1.4e-13 51.0 3.7 8.1e-05 22.9 0.0 5.3 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM66327.1 - 0.0017 17.7 6.5 0.014 14.7 1.0 3.3 2 2 1 3 3 3 2 WD40-like domain RAB3GAP2_N PF14655.6 KFM66327.1 - 0.0089 15.3 0.5 0.85 8.8 0.0 3.0 3 1 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 KFM66327.1 - 0.088 11.7 2.0 0.57 9.1 0.3 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribonucleas_3_3 PF14622.6 KFM66328.1 - 2.1e-07 31.1 0.0 4.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFM66328.1 - 0.12 13.0 0.1 1.3 9.6 0.1 2.2 1 1 0 1 1 1 0 Ribonuclease III domain Glyco_trans_1_4 PF13692.6 KFM66331.1 - 0.00016 22.1 0.0 0.00022 21.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KFM66331.1 - 0.00021 20.9 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 MyTH4 PF00784.17 KFM66333.1 - 9.2e-12 45.4 0.0 9.7e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 MyTH4 domain zf-H2C2_2 PF13465.6 KFM66334.1 - 6.2e-06 26.4 0.2 6.2e-06 26.4 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66334.1 - 0.0001 22.6 1.4 0.00015 22.1 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM66334.1 - 0.00074 19.4 0.3 0.0012 18.8 0.3 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFM66334.1 - 0.00091 19.9 1.0 0.0013 19.4 1.0 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 KFM66334.1 - 0.0054 17.1 0.1 0.0098 16.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM66334.1 - 0.033 14.5 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding HTH_Tnp_Tc3_2 PF01498.18 KFM66335.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66335.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HIG_1_N PF04588.13 KFM66337.1 - 3.2e-20 72.1 3.9 4.2e-20 71.7 3.9 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Yip1 PF04893.17 KFM66337.1 - 0.013 15.3 0.0 0.016 14.9 0.0 1.0 1 0 0 1 1 1 0 Yip1 domain RVT_1 PF00078.27 KFM66338.1 - 1.4e-53 181.7 0.0 1.9e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 KFM66339.1 - 6e-108 348.9 107.1 2.6e-09 37.1 0.2 15.3 14 1 0 15 15 15 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66339.1 - 5.9e-75 243.8 120.4 2.7e-06 27.5 0.1 14.2 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66339.1 - 8.8e-54 175.5 111.4 0.001 19.7 0.4 14.2 14 0 0 14 14 14 14 C2H2-type zinc finger zf-met PF12874.7 KFM66339.1 - 1.7e-42 142.6 104.4 0.00027 21.2 2.2 14.4 14 0 0 14 14 14 14 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM66339.1 - 1.5e-24 85.4 63.8 0.00057 19.6 0.1 14.2 14 0 0 14 14 14 9 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM66339.1 - 8.1e-23 79.9 105.8 0.00044 20.2 2.3 14.4 14 0 0 14 14 14 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM66339.1 - 4.7e-18 65.0 87.5 0.0028 17.9 0.3 15.0 14 1 0 14 14 14 8 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM66339.1 - 1.3e-09 38.2 15.3 0.014 15.7 0.1 8.1 1 1 5 7 7 7 1 BolA-like protein ADK_lid PF05191.14 KFM66339.1 - 4.3e-09 36.2 40.3 0.016 15.2 0.2 8.6 4 2 3 8 8 8 6 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM66339.1 - 1.3e-07 31.3 53.0 0.26 11.2 0.1 13.8 14 0 0 14 14 14 2 zinc-finger of a C2HC-type GAGA PF09237.11 KFM66339.1 - 4.5e-05 23.2 35.9 0.12 12.2 0.2 9.6 3 3 8 11 11 11 3 GAGA factor Tox-HNH-HHH PF15637.6 KFM66339.1 - 9.8e-05 22.5 8.0 9.8 6.4 0.2 5.8 2 2 4 7 7 7 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif FYVE PF01363.21 KFM66339.1 - 0.00025 21.1 76.5 0.019 15.1 10.1 7.4 2 2 5 7 7 7 3 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 KFM66339.1 - 0.0004 20.4 60.4 0.28 11.3 0.1 13.1 11 2 3 14 14 14 2 Sec23/Sec24 zinc finger DUF2256 PF10013.9 KFM66339.1 - 0.0016 18.5 57.3 13 6.0 0.2 13.8 14 0 0 14 14 14 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_1 PF00130.22 KFM66339.1 - 0.003 17.4 74.9 0.44 10.5 6.5 11.9 4 3 6 11 11 11 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3396 PF11876.8 KFM66339.1 - 0.037 13.5 0.0 58 3.1 0.0 4.6 1 1 5 7 7 7 0 Protein of unknown function (DUF3396) zf-CHCC PF10276.9 KFM66339.1 - 0.047 13.8 23.8 74 3.5 0.0 11.3 14 0 0 14 14 14 0 Zinc-finger domain zf-C2H2_11 PF16622.5 KFM66339.1 - 0.068 12.9 0.5 0.068 12.9 0.5 11.7 13 0 0 13 13 12 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFM66339.1 - 0.17 12.7 57.6 0.5 11.2 1.6 7.3 2 1 3 7 7 7 0 zinc-ribbon family zf-HIT PF04438.16 KFM66339.1 - 0.25 11.2 84.2 0.19 11.7 2.0 13.4 14 0 0 14 14 14 0 HIT zinc finger zf-MYST PF17772.1 KFM66339.1 - 0.39 10.4 0.1 0.39 10.4 0.1 12.9 7 4 7 14 14 14 0 MYST family zinc finger domain zf-DBF PF07535.12 KFM66339.1 - 0.41 10.8 67.7 3.4 7.9 0.1 13.1 14 0 0 14 14 14 0 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM66339.1 - 1.8 8.7 60.3 6.7 6.9 5.6 6.8 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type PqqA PF08042.11 KFM66339.1 - 2.4 8.3 8.0 4.6e+02 1.1 0.0 6.8 9 0 0 9 9 9 0 PqqA family zf-C2H2_9 PF16293.5 KFM66339.1 - 7.3 6.5 64.7 2.3 8.1 1.3 13.0 2 2 12 14 14 14 0 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 KFM66340.1 - 3.1e-51 169.6 49.1 1.5e-09 37.9 0.8 9.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66340.1 - 3.9e-38 127.8 66.8 5.1e-06 26.6 2.9 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66340.1 - 4.1e-29 98.7 62.5 0.00029 21.4 1.3 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM66340.1 - 2e-18 66.1 60.5 0.00098 19.4 1.4 8.2 8 0 0 8 8 8 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM66340.1 - 1.3e-12 47.3 55.8 0.021 14.8 0.8 8.3 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM66340.1 - 2.8e-12 46.6 46.3 0.015 15.6 0.2 8.3 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM66340.1 - 6.4e-08 32.2 32.4 0.013 15.3 0.6 8.1 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM66340.1 - 2e-06 27.8 30.0 0.097 12.7 0.1 7.7 3 2 5 8 8 8 3 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM66340.1 - 0.0011 19.0 34.7 0.22 11.6 4.1 4.0 1 1 3 4 4 4 2 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM66340.1 - 0.0013 18.8 27.4 6.9 6.9 0.1 7.9 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Baculo_IE-1 PF05290.11 KFM66340.1 - 0.0043 17.0 30.1 4.4 7.3 10.2 6.0 1 1 3 4 4 4 1 Baculovirus immediate-early protein (IE-0) zf-MYST PF17772.1 KFM66340.1 - 0.008 15.8 42.2 0.36 10.5 0.7 7.8 1 1 7 8 8 8 2 MYST family zinc finger domain FYVE PF01363.21 KFM66340.1 - 0.0095 16.1 9.6 0.0095 16.1 9.6 4.8 2 2 1 4 4 4 1 FYVE zinc finger zf-DBF PF07535.12 KFM66340.1 - 0.018 15.2 32.9 15 5.8 0.1 7.8 8 0 0 8 8 8 0 DBF zinc finger TRAF6_Z2 PF18048.1 KFM66340.1 - 0.019 15.0 26.6 7 6.8 0.2 7.8 8 0 0 8 8 8 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_8 PF15909.5 KFM66340.1 - 0.03 14.6 4.9 0.03 14.6 4.9 4.1 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf-BED PF02892.15 KFM66340.1 - 0.036 14.1 56.8 1.2 9.2 3.0 8.1 1 1 7 8 8 8 0 BED zinc finger DZR PF12773.7 KFM66340.1 - 0.041 13.9 23.2 1.8e+04 -9.3 23.2 4.9 1 1 0 1 1 0 0 Double zinc ribbon zf-C2H2_2 PF12756.7 KFM66340.1 - 0.078 13.3 1.1 0.078 13.3 1.1 7.6 1 1 5 7 7 7 0 C2H2 type zinc-finger (2 copies) Tox-HNH-HHH PF15637.6 KFM66340.1 - 0.1 12.8 1.8 11 6.3 0.0 3.0 1 1 1 3 3 3 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif ADK_lid PF05191.14 KFM66340.1 - 0.34 10.9 30.9 0.52 10.3 1.0 5.8 4 2 0 4 4 4 0 Adenylate kinase, active site lid IGPD PF00475.18 KFM66340.1 - 0.45 10.8 9.9 11 6.3 0.2 4.3 1 1 3 5 5 5 0 Imidazoleglycerol-phosphate dehydratase zf-C2H2_9 PF16293.5 KFM66340.1 - 1.1 9.1 36.7 2.1 8.3 0.4 7.5 2 1 6 8 8 8 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM66340.1 - 1.2 9.0 12.5 8.5 6.3 0.5 4.8 2 1 3 6 6 6 0 GAGA factor C5HCH PF17982.1 KFM66340.1 - 2 8.6 34.2 23 5.2 0.9 7.7 5 1 3 8 8 8 0 NSD Cys-His rich domain Zf_RING PF16744.5 KFM66340.1 - 3.5 7.8 38.0 10 6.3 0.3 7.6 1 1 7 8 8 7 0 KIAA1045 RING finger zf-C2H2_11 PF16622.5 KFM66340.1 - 3.9 7.3 46.7 0.17 11.7 1.4 7.3 8 0 0 8 8 8 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFM66340.1 - 5.3 7.9 34.3 1.1 10.1 3.0 4.5 1 1 3 5 5 5 0 zinc-ribbon family zf-C2HC_2 PF13913.6 KFM66340.1 - 5.9 6.9 29.8 1.1 9.2 0.1 6.8 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM66340.1 - 7.8 6.2 31.2 3.2 7.4 0.1 7.6 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFM66340.1 - 8.1 7.1 31.0 2.7 8.7 1.9 5.1 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats SapB_2 PF03489.17 KFM66342.1 - 6.8e-14 51.7 14.5 9.1e-08 32.1 0.6 3.3 4 0 0 4 4 4 2 Saposin-like type B, region 2 SapB_1 PF05184.15 KFM66342.1 - 4e-12 45.9 11.8 1.5e-07 31.3 5.7 2.9 2 0 0 2 2 2 2 Saposin-like type B, region 1 SapA PF02199.15 KFM66342.1 - 4.2e-11 42.9 7.8 4.2e-11 42.9 7.8 2.5 3 0 0 3 3 3 1 Saposin A-type domain MitMem_reg PF13012.6 KFM66342.1 - 0.001 19.5 0.1 0.14 12.6 0.0 2.2 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function DUF3456 PF11938.8 KFM66342.1 - 0.0049 17.4 6.5 0.3 11.6 1.2 3.0 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP GTP_EFTU PF00009.27 KFM66345.1 - 8e-36 123.4 0.0 3.9e-35 121.2 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFM66345.1 - 2.6e-21 75.7 0.2 9.7e-21 73.9 0.2 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 KFM66345.1 - 3.6e-16 58.8 0.0 8.9e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 KFM66345.1 - 6.4e-12 45.7 7.4 4e-07 30.3 0.0 4.5 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM66345.1 - 7.5e-08 32.5 0.2 7.8e-07 29.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFM66345.1 - 4e-06 26.8 0.3 7.7e-05 22.6 0.0 3.3 2 1 1 3 3 3 1 Conserved hypothetical ATP binding protein Roc PF08477.13 KFM66345.1 - 0.00012 22.3 0.0 0.00042 20.5 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM66345.1 - 0.032 13.8 0.0 0.093 12.3 0.0 1.9 1 0 0 1 1 1 0 Ras family CBM_14 PF01607.24 KFM66346.1 - 2.6e-36 123.5 23.2 7.9e-15 54.8 3.0 3.5 3 1 1 4 4 4 3 Chitin binding Peritrophin-A domain FKBP_C PF00254.28 KFM66347.1 - 1.9e-12 47.4 0.0 6.5e-12 45.6 0.0 2.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Csm1_N PF18504.1 KFM66347.1 - 0.0083 16.4 4.9 0.0083 16.4 4.9 7.0 4 1 2 6 6 6 1 Csm1 N-terminal domain Fumble PF03630.14 KFM66347.1 - 1.4 8.1 5.5 3.4 6.7 5.5 1.7 1 0 0 1 1 1 0 Fumble DDE_3 PF13358.6 KFM66348.1 - 2.9e-13 49.8 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ctr PF04145.15 KFM66349.1 - 2.9e-36 125.3 10.5 6.9e-36 124.1 10.5 1.6 1 1 0 1 1 1 1 Ctr copper transporter family DUF2292 PF10055.9 KFM66349.1 - 0.024 14.2 0.1 0.053 13.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) DUF4191 PF13829.6 KFM66349.1 - 3.6 6.9 7.9 0.16 11.3 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) AMP-binding PF00501.28 KFM66350.1 - 7.1e-72 242.3 0.0 9.4e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM66350.1 - 8.5e-06 26.7 0.0 1.6e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DDE_3 PF13358.6 KFM66351.1 - 9.1e-05 22.2 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC_3 PF13917.6 KFM66352.1 - 1.1e-16 60.4 3.8 2e-16 59.6 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle DDHD PF02862.17 KFM66352.1 - 0.044 13.9 8.4 0.051 13.7 8.4 1.0 1 0 0 1 1 1 0 DDHD domain Macoilin PF09726.9 KFM66352.1 - 0.79 8.2 19.6 0.77 8.2 19.6 1.0 1 0 0 1 1 1 0 Macoilin family AF-4 PF05110.13 KFM66352.1 - 0.85 7.6 33.4 0.93 7.5 33.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Lin-8 PF03353.15 KFM66352.1 - 2 7.9 8.1 2.3 7.7 8.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Striatin PF08232.12 KFM66352.1 - 2.8 8.5 8.3 3.8 8.1 8.3 1.2 1 0 0 1 1 1 0 Striatin family Hid1 PF12722.7 KFM66352.1 - 3.6 5.6 11.3 3.6 5.6 11.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_capsid PF06112.11 KFM66352.1 - 4.7 7.2 22.8 5.7 7.0 22.8 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SAPS PF04499.15 KFM66352.1 - 7.2 5.3 8.8 6.8 5.3 8.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 KFM66352.1 - 8.7 5.1 22.1 9.4 5.0 22.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain BTB_2 PF02214.22 KFM66353.1 - 2.3e-05 24.7 0.0 2.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain HTH_Tnp_Tc3_2 PF01498.18 KFM66354.1 - 3.8e-16 59.1 3.4 5.4e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66354.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66354.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66354.1 - 0.0025 17.6 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66354.1 - 1.8 9.2 15.6 0.12 13.1 1.9 3.3 2 1 1 3 3 3 0 Homeodomain-like domain CPG4 PF15481.6 KFM66355.1 - 0.015 15.9 0.4 0.016 15.9 0.4 1.1 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 DUF1397 PF07165.11 KFM66355.1 - 0.024 14.1 0.2 0.027 13.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) DHC_N2 PF08393.13 KFM66355.1 - 0.077 12.1 0.0 0.078 12.1 0.0 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Ly-6_related PF06579.12 KFM66356.1 - 0.0097 16.2 0.7 0.011 15.9 0.7 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein CN_hydrolase PF00795.22 KFM66357.1 - 7e-40 137.0 0.0 1e-39 136.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KFM66357.1 - 7.3e-30 103.8 0.1 2.1e-29 102.4 0.1 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFM66357.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase Mob1_phocein PF03637.17 KFM66358.1 - 1.2e-35 123.1 0.5 1.4e-35 122.8 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family SVWC PF15430.6 KFM66358.1 - 0.12 12.7 1.6 0.26 11.6 1.6 1.6 1 0 0 1 1 1 0 Single domain von Willebrand factor type C HTH_Tnp_Tc3_2 PF01498.18 KFM66359.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66359.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66359.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66359.1 - 0.0026 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66359.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Mem_trans PF03547.18 KFM66360.1 - 5.9e-13 48.0 25.6 2.2e-10 39.5 4.8 3.6 2 2 0 3 3 3 2 Membrane transport protein DEP PF00610.21 KFM66360.1 - 0.00025 21.0 0.0 0.00066 19.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2109 PF09882.9 KFM66360.1 - 7.3 6.7 7.1 1.7 8.7 0.3 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) Ion_trans_2 PF07885.16 KFM66363.1 - 1.9e-37 127.1 14.2 1e-18 67.0 4.4 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFM66363.1 - 9.7e-08 31.5 7.2 1.8e-05 24.1 0.1 2.4 2 1 0 2 2 2 2 Ion transport protein IRK PF01007.20 KFM66363.1 - 0.021 14.6 0.1 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF5392 PF17370.2 KFM66363.1 - 0.27 11.3 0.6 20 5.3 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5392) Neur_chan_memb PF02932.16 KFM66365.1 - 1.6e-09 38.2 1.7 1.5e-05 25.2 1.7 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region zf-H2C2_2 PF13465.6 KFM66366.1 - 3.7e-33 112.5 29.1 3.9e-09 36.5 0.2 6.1 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66366.1 - 5.5e-23 80.1 31.4 6.9e-06 26.2 0.2 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66366.1 - 6.6e-18 63.9 33.9 0.00036 21.1 0.3 5.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM66366.1 - 2.5e-08 33.5 23.4 0.016 15.0 0.2 5.4 6 0 0 6 6 6 4 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM66366.1 - 3.8e-08 33.1 18.9 0.05 13.6 0.2 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM66366.1 - 1.3e-05 24.9 14.7 0.65 9.9 0.0 5.0 1 1 4 5 5 5 2 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 KFM66366.1 - 5e-05 23.5 26.6 0.23 11.9 1.5 4.8 5 0 0 5 5 4 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM66366.1 - 0.00012 21.8 23.9 0.074 12.8 0.5 5.2 5 0 0 5 5 5 4 C2H2-type zinc-finger domain BolA PF01722.18 KFM66366.1 - 0.00015 21.9 4.9 2 8.8 0.1 4.3 1 1 3 4 4 4 2 BolA-like protein RNA_POL_M_15KD PF02150.16 KFM66366.1 - 0.0014 18.4 2.2 13 5.7 0.0 4.3 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit zf-C2H2_jaz PF12171.8 KFM66366.1 - 0.0016 18.6 12.0 4.7 7.6 0.0 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding Cas_CXXC_CXXC PF09706.10 KFM66366.1 - 0.0029 17.8 6.9 0.31 11.3 0.1 3.9 3 2 1 4 4 4 1 CRISPR-associated protein (Cas_CXXC_CXXC) zf-MYST PF17772.1 KFM66366.1 - 0.0042 16.7 17.3 0.11 12.1 2.1 4.3 2 2 2 4 4 4 1 MYST family zinc finger domain GAGA PF09237.11 KFM66366.1 - 0.0077 16.0 5.8 0.59 10.0 0.1 4.3 1 1 4 5 5 5 1 GAGA factor K_oxygenase PF13434.6 KFM66366.1 - 0.023 13.8 0.1 3.8 6.6 0.0 2.6 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Inhibitor_I67 PF11405.8 KFM66366.1 - 0.099 12.9 1.2 0.099 12.9 1.2 3.5 4 0 0 4 4 3 0 Bromelain inhibitor VI zf-C2H2_2 PF12756.7 KFM66366.1 - 0.12 12.7 23.6 2.5 8.5 1.0 4.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM66366.1 - 0.13 13.0 11.3 0.66 10.8 2.3 2.5 1 1 1 2 2 2 0 zinc-ribbon family DZR PF12773.7 KFM66366.1 - 0.23 11.5 8.9 3.9 7.6 1.1 2.7 1 1 1 2 2 2 0 Double zinc ribbon Zf_RING PF16744.5 KFM66366.1 - 0.26 11.4 19.1 13 5.9 0.3 4.8 1 1 4 5 5 5 0 KIAA1045 RING finger zf-RRPl_C4 PF17026.5 KFM66366.1 - 0.5 10.5 17.0 1.9 8.6 5.0 2.9 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_4 PF07975.12 KFM66366.1 - 0.83 9.9 18.4 0.94 9.8 9.9 3.4 1 1 3 4 4 4 0 TFIIH C1-like domain TRAF6_Z2 PF18048.1 KFM66366.1 - 1.1 9.4 13.5 14 5.9 0.1 4.8 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 DUF2256 PF10013.9 KFM66366.1 - 1.2 9.3 15.6 1.8 8.7 0.1 4.8 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_8 PF15909.5 KFM66366.1 - 1.3 9.4 16.2 0.4 11.0 3.0 2.7 1 1 2 3 3 3 0 C2H2-type zinc ribbon A2L_zn_ribbon PF08792.10 KFM66366.1 - 1.3 8.8 15.1 5.2 6.9 0.1 4.6 5 0 0 5 5 5 0 A2L zinc ribbon domain zf_C2H2_ZHX PF18387.1 KFM66366.1 - 1.6 8.5 13.2 1.3 8.7 1.3 3.5 4 0 0 4 4 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-trcl PF13451.6 KFM66366.1 - 1.9 8.5 12.3 38 4.3 0.1 4.4 4 0 0 4 4 4 0 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFM66366.1 - 4.1 7.6 16.1 2.1 8.5 2.0 3.6 1 1 3 4 4 4 0 Zinc ribbon domain XPA_N PF01286.18 KFM66366.1 - 4.4 7.4 11.9 17 5.5 0.7 4.1 4 0 0 4 4 4 0 XPA protein N-terminal zf-H2C2_2 PF13465.6 KFM66367.1 - 1.3e-68 224.5 66.4 5e-09 36.2 0.7 10.3 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66367.1 - 7.6e-40 133.2 70.2 1.1e-05 25.7 0.5 9.2 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66367.1 - 1.4e-31 106.4 70.9 0.00061 20.4 0.5 9.3 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM66367.1 - 1.1e-15 57.2 58.1 0.015 15.3 1.7 9.6 9 0 0 9 9 9 7 C2H2-type zinc finger zf-met PF12874.7 KFM66367.1 - 3.4e-14 52.7 55.4 0.0076 16.6 0.6 9.6 9 0 0 9 9 9 6 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM66367.1 - 4.4e-14 51.9 52.2 0.0072 16.1 0.4 9.2 9 0 0 9 9 9 7 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM66367.1 - 4.9e-08 32.9 29.8 0.78 9.8 0.0 9.0 3 2 6 9 9 9 3 Sec23/Sec24 zinc finger BolA PF01722.18 KFM66367.1 - 8.3e-08 32.4 6.6 1.1 9.5 0.0 6.0 1 1 4 6 6 6 3 BolA-like protein zf-C2H2_jaz PF12171.8 KFM66367.1 - 3.7e-07 30.2 46.0 0.45 10.9 0.1 9.4 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding TRAF6_Z2 PF18048.1 KFM66367.1 - 0.0013 18.7 44.3 0.38 10.9 1.6 8.8 9 0 0 9 9 9 3 TNF receptor-associated factor 6 zinc finger 2 GAGA PF09237.11 KFM66367.1 - 0.0041 16.9 24.0 4.3 7.2 0.3 7.5 1 1 8 9 9 9 2 GAGA factor Tox-HNH-HHH PF15637.6 KFM66367.1 - 0.0046 17.1 0.1 0.59 10.3 0.0 3.7 2 2 3 5 5 5 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif Scramblase PF03803.15 KFM66367.1 - 0.014 14.7 8.9 0.23 10.7 1.4 2.4 2 1 0 2 2 2 0 Scramblase Amidohydro_1 PF01979.20 KFM66367.1 - 0.016 14.5 4.9 8.2 5.6 0.2 4.5 1 1 2 5 5 5 0 Amidohydrolase family DUF1241 PF06840.11 KFM66367.1 - 0.019 14.6 0.1 14 5.3 0.0 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1241) zf-DBF PF07535.12 KFM66367.1 - 0.021 14.9 44.5 15 5.8 0.2 9.2 9 0 0 9 9 9 0 DBF zinc finger GATase_2 PF00310.21 KFM66367.1 - 0.059 12.1 0.7 1.2 7.8 0.1 2.0 2 0 0 2 2 2 0 Glutamine amidotransferases class-II zf-C2H2_9 PF16293.5 KFM66367.1 - 0.19 11.6 37.8 9.3 6.2 0.2 8.6 4 3 5 9 9 9 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM66367.1 - 3.2 7.8 41.7 6 6.9 0.1 9.0 9 0 0 9 9 9 0 zinc-finger of a C2HC-type DUF5330 PF17264.2 KFM66367.1 - 5.1 7.2 30.4 10 6.2 0.1 7.5 8 0 0 8 8 7 0 Family of unknown function (DUF5330) DDE_1 PF03184.19 KFM66369.1 - 3.5e-19 69.1 0.2 7.2e-19 68.1 0.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_16 PF10294.9 KFM66369.1 - 9.2e-06 25.5 0.1 1.6e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KFM66369.1 - 0.035 13.9 0.0 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFM66369.1 - 0.049 14.4 0.0 0.36 11.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain FTHFS PF01268.19 KFM66370.1 - 3.7e-252 837.5 0.4 4.6e-252 837.2 0.4 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH PF00763.23 KFM66370.1 - 6.2e-14 52.3 0.6 1.9e-13 50.7 0.6 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KFM66370.1 - 2.3e-13 49.8 0.6 8.5e-13 47.9 0.6 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CbiA PF01656.23 KFM66370.1 - 0.16 12.0 0.1 0.72 9.9 0.1 2.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain EF-hand_6 PF13405.6 KFM66371.1 - 3e-22 76.6 1.3 1.7e-06 27.5 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 KFM66371.1 - 3.1e-22 76.4 6.7 4.4e-08 32.1 0.0 5.1 5 1 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KFM66371.1 - 5.7e-22 77.9 3.5 3e-12 46.8 0.8 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM66371.1 - 6.6e-16 57.0 5.1 1.1e-05 24.7 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFM66371.1 - 1.5e-10 40.8 10.8 2.3e-07 30.5 0.5 4.4 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 KFM66371.1 - 0.0013 19.0 2.1 5.2 7.5 0.0 3.8 2 2 2 4 4 4 1 EF-hand domain NAC PF01849.18 KFM66372.1 - 1.4e-12 47.4 0.1 2.3e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 NAC domain TerB_C PF15615.6 KFM66372.1 - 0.035 14.4 0.3 0.049 13.9 0.3 1.2 1 0 0 1 1 1 0 TerB-C domain ACTH_assoc PF16102.5 KFM66372.1 - 0.24 12.3 2.5 0.49 11.3 2.5 1.6 1 0 0 1 1 1 0 ACTH-associated domain WD40 PF00400.32 KFM66373.1 - 4.7e-22 77.9 2.1 7.5e-12 45.6 0.2 2.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM66373.1 - 1.5e-06 28.4 0.0 2.3e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM66373.1 - 0.00025 21.0 0.0 0.012 15.5 0.0 1.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A nos_propeller PF18764.1 KFM66373.1 - 0.081 12.8 0.1 3.1 7.8 0.1 2.1 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat HTH_Tnp_Tc3_2 PF01498.18 KFM66374.1 - 2.4e-16 59.7 2.2 5.5e-16 58.6 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66374.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66374.1 - 9.8e-07 28.4 0.8 4.3e-06 26.4 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66374.1 - 0.005 16.6 0.3 0.014 15.2 0.3 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66374.1 - 3.3 8.4 14.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM66375.1 - 4.5e-16 58.9 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66375.1 - 7.4e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM66375.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM66375.1 - 0.002 17.8 0.1 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66375.1 - 0.015 15.4 0.7 0.063 13.4 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM66375.1 - 0.034 14.2 0.4 0.034 14.2 0.4 2.6 3 0 0 3 3 3 0 Winged helix-turn helix PIF1 PF05970.14 KFM66376.1 - 3.5e-15 56.0 0.0 4.5e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 KFM66376.1 - 0.2 9.6 0.0 0.25 9.2 0.0 1.1 1 0 0 1 1 1 0 Helicase DDE_Tnp_1_7 PF13843.6 KFM66377.1 - 9.1e-46 156.8 0.1 1e-45 156.6 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 GCP_N_terminal PF17681.1 KFM66378.1 - 3.2e-17 63.1 0.0 3.9e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFM66380.1 - 4.1e-14 52.7 0.1 4.9e-14 52.5 0.1 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal IQ PF00612.27 KFM66382.1 - 2.9e-05 23.5 0.4 4.9e-05 22.8 0.4 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif TTC5_OB PF16669.5 KFM66386.1 - 0.044 13.5 0.0 0.048 13.3 0.0 1.0 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain HECT PF00632.25 KFM66388.1 - 6.6e-66 222.9 0.0 1e-65 222.2 0.0 1.3 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Opiods_neuropep PF01160.18 KFM66389.1 - 0.044 13.9 0.1 0.057 13.5 0.1 1.1 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Transposase_1 PF01359.18 KFM66391.1 - 1.1e-21 76.5 0.2 2.3e-21 75.4 0.2 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_32 PF13565.6 KFM66391.1 - 7.9e-07 29.6 1.4 2.3e-06 28.1 0.0 2.6 3 1 0 3 3 3 1 Homeodomain-like domain DDE_3 PF13358.6 KFM66391.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66391.1 - 0.079 13.2 0.4 0.28 11.5 0.3 2.0 2 0 0 2 2 2 0 Transposase HTH_29 PF13551.6 KFM66391.1 - 0.084 12.9 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 KFM66391.1 - 0.11 12.6 0.1 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LRR_8 PF13855.6 KFM66392.1 - 1.1e-52 175.7 63.1 7e-17 61.0 3.0 6.9 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFM66392.1 - 5.4e-24 84.6 3.0 2.5e-11 43.6 0.0 3.2 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM66392.1 - 3.9e-22 78.0 39.6 8.2e-07 29.3 1.8 7.9 4 2 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM66392.1 - 2.1e-11 42.7 37.9 0.89 10.3 0.2 11.9 10 2 1 11 11 11 5 Leucine Rich Repeat LRR_9 PF14580.6 KFM66392.1 - 1.4e-10 40.9 15.6 0.00022 20.8 3.6 4.2 1 1 3 4 4 4 3 Leucine-rich repeat LRRNT PF01462.18 KFM66392.1 - 0.013 15.2 1.6 0.013 15.2 1.6 2.8 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFM66392.1 - 5.2 7.4 34.4 7.3 6.9 0.1 9.5 10 0 0 10 10 10 0 Leucine Rich repeat HTH_Tnp_Tc3_2 PF01498.18 KFM66393.1 - 2.4e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66393.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 KFM66396.1 - 1.9e-05 24.1 0.1 2.1e-05 24.0 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF4371 PF14291.6 KFM66397.1 - 0.0048 16.6 0.0 0.0053 16.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Calx-beta PF03160.14 KFM66399.1 - 1e-48 163.6 3.4 1.6e-30 105.3 0.9 2.8 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex_C PF16494.5 KFM66399.1 - 2.1e-39 134.9 0.6 3.5e-39 134.2 0.6 1.3 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain Na_Ca_ex PF01699.24 KFM66399.1 - 1.7e-28 99.5 10.7 2.5e-28 99.0 10.7 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Vpu PF00558.19 KFM66399.1 - 0.054 13.3 0.1 0.22 11.3 0.1 2.0 1 0 0 1 1 1 0 Vpu protein Type2_restr_D3 PF16902.5 KFM66399.1 - 0.11 12.5 2.7 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain PDZ PF00595.24 KFM66401.1 - 3.3e-16 59.4 0.0 4.2e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM66401.1 - 1.6e-07 31.0 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM66401.1 - 3.9e-07 30.3 0.0 5.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PIF1 PF05970.14 KFM66403.1 - 7.6e-06 25.3 0.6 1e-05 24.9 0.6 1.2 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 KFM66403.1 - 0.00063 17.8 0.0 0.00079 17.5 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KFM66403.1 - 0.0035 17.2 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DDE_3 PF13358.6 KFM66404.1 - 1.8e-15 56.9 0.1 5.9e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66404.1 - 1.2e-14 54.3 6.0 2.2e-14 53.5 6.0 1.5 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM66404.1 - 0.017 15.3 0.1 0.06 13.5 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM66404.1 - 0.019 14.7 0.0 0.11 12.3 0.0 2.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 KFM66404.1 - 0.021 14.8 0.6 0.066 13.2 0.6 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 KFM66404.1 - 0.049 14.2 1.1 0.049 14.2 1.1 2.7 2 1 0 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.6 KFM66405.1 - 5.1e-16 58.7 0.1 5.9e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66405.1 - 7.8e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM66405.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM66405.1 - 0.0025 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66405.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM66405.1 - 0.03 14.3 2.6 0.035 14.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM66406.1 - 1.3e-10 41.2 0.0 1.4e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Aldo_ket_red PF00248.21 KFM66407.1 - 3.7e-46 157.6 0.1 1e-44 152.9 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LRRFIP PF09738.9 KFM66408.1 - 3.1e-70 237.0 27.7 3.1e-70 237.0 27.7 2.1 2 0 0 2 2 2 1 LRRFIP family Syntaxin-6_N PF09177.11 KFM66408.1 - 0.00018 22.0 21.1 0.0018 18.8 6.5 3.7 2 1 2 4 4 4 2 Syntaxin 6, N-terminal Laminin_II PF06009.12 KFM66408.1 - 0.00046 20.2 23.8 0.049 13.6 1.2 3.4 2 1 2 4 4 4 3 Laminin Domain II FPP PF05911.11 KFM66408.1 - 0.00062 18.1 33.6 0.00064 18.1 21.3 2.1 2 0 0 2 2 2 2 Filament-like plant protein, long coiled-coil DUF4164 PF13747.6 KFM66408.1 - 0.0012 19.0 12.5 0.0012 19.0 12.5 3.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) BST2 PF16716.5 KFM66408.1 - 0.0028 18.2 10.6 0.0028 18.2 10.6 4.0 3 2 2 5 5 4 1 Bone marrow stromal antigen 2 DUF1664 PF07889.12 KFM66408.1 - 0.0047 17.0 22.1 0.59 10.2 1.4 4.3 2 1 1 4 4 4 2 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 KFM66408.1 - 0.0048 17.1 37.8 0.017 15.3 11.9 4.2 2 2 1 3 3 3 2 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 KFM66408.1 - 0.0062 16.6 17.0 0.0062 16.6 17.0 3.9 3 1 1 4 4 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KFM66408.1 - 0.0075 15.6 9.0 0.0075 15.6 9.0 4.6 2 2 1 4 4 4 1 Protein of unknown function (DUF3450) CALCOCO1 PF07888.11 KFM66408.1 - 0.0098 14.8 44.1 0.22 10.3 24.5 2.2 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4472 PF14739.6 KFM66408.1 - 0.012 16.3 3.2 0.012 16.3 3.2 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4472) MAD PF05557.13 KFM66408.1 - 0.013 13.9 40.0 0.0037 15.7 26.9 2.2 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF724 PF05266.14 KFM66408.1 - 0.015 15.1 11.3 0.015 15.1 11.3 3.4 2 1 1 4 4 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 KFM66408.1 - 0.029 14.7 20.3 0.89 10.0 1.6 5.1 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 KFM66408.1 - 0.068 13.3 39.6 0.59 10.3 4.3 5.8 4 2 1 5 5 5 0 bZIP transcription factor HOOK PF05622.12 KFM66408.1 - 0.11 10.6 44.2 0.14 10.2 16.7 3.0 1 1 2 3 3 3 0 HOOK protein Mei5 PF10376.9 KFM66408.1 - 0.18 11.7 36.4 0.027 14.3 1.7 3.3 2 1 1 3 3 3 0 Double-strand recombination repair protein DUF2968 PF11180.8 KFM66408.1 - 0.28 10.8 24.7 0.18 11.4 12.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) GIT_CC PF16559.5 KFM66408.1 - 0.73 9.7 21.8 0.81 9.6 3.4 5.0 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor ATG16 PF08614.11 KFM66408.1 - 0.88 9.8 44.7 0.34 11.1 6.8 3.4 1 1 2 3 3 2 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 KFM66408.1 - 1.8 8.3 37.9 0.41 10.4 5.9 4.6 2 2 2 4 4 4 0 Phage minor structural protein GP20 LPP PF04728.13 KFM66408.1 - 2.3 8.7 15.2 1 9.8 0.3 5.4 4 3 1 5 5 4 0 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.12 KFM66408.1 - 2.3 8.3 53.7 0.3 11.1 26.1 5.1 3 2 1 4 4 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 KFM66408.1 - 2.8 8.5 50.0 3.4 8.2 9.5 4.9 2 2 1 3 3 3 0 Cell division protein ZapB GAS PF13851.6 KFM66408.1 - 3.1 7.1 47.0 0.032 13.6 11.8 4.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KFM66408.1 - 3.1 7.9 40.3 1.3 9.1 17.1 4.1 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 KFM66408.1 - 3.3 8.2 13.6 11 6.5 3.2 4.0 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HAP1_N PF04849.13 KFM66408.1 - 3.6 6.7 45.6 3.5 6.7 5.7 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region BLOC1_2 PF10046.9 KFM66408.1 - 3.7 7.9 32.4 0.25 11.7 0.9 5.0 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 KFM66408.1 - 3.8 8.1 56.5 0.29 11.6 18.2 3.7 1 1 2 3 3 3 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 KFM66408.1 - 4 5.2 26.5 1.2 6.9 11.1 2.2 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Med9 PF07544.13 KFM66408.1 - 4.1 7.6 24.8 0.31 11.1 1.2 4.3 3 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 CP12 PF02672.15 KFM66408.1 - 4.4 8.1 12.0 2.1 9.2 2.7 3.7 3 1 0 3 3 3 0 CP12 domain Occludin_ELL PF07303.13 KFM66408.1 - 4.4 8.1 25.6 0.81 10.4 8.7 3.8 2 2 1 3 3 3 0 Occludin homology domain Med10 PF09748.9 KFM66408.1 - 6.8 6.7 11.0 17 5.4 0.9 3.4 2 2 1 3 3 3 0 Transcription factor subunit Med10 of Mediator complex KASH_CCD PF14662.6 KFM66408.1 - 8.5 6.2 46.9 0.81 9.5 8.9 3.6 2 2 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 KFM66408.1 - 8.9 4.8 30.7 4.1 5.9 19.6 2.5 1 1 0 2 2 2 0 AAA domain DUF745 PF05335.13 KFM66408.1 - 9.1 6.0 25.5 0.17 11.6 11.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Golgin_A5 PF09787.9 KFM66410.1 - 0.00093 18.7 37.3 0.00093 18.7 37.3 14.6 2 2 11 15 15 15 1 Golgin subfamily A member 5 AAA_assoc_2 PF16193.5 KFM66410.1 - 1.7 9.0 7.9 10 6.6 0.1 5.4 2 1 1 3 3 3 0 AAA C-terminal domain DUF1269 PF06897.12 KFM66410.1 - 1.8 8.9 6.0 2.6 8.4 2.0 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) GTP_EFTU PF00009.27 KFM66411.1 - 7.4e-47 159.4 0.0 1.1e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KFM66411.1 - 3.1e-38 131.1 12.1 6e-38 130.2 12.1 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KFM66411.1 - 2e-25 88.9 0.0 4.2e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KFM66411.1 - 5.3e-23 80.9 0.0 1.2e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFM66411.1 - 1.8e-13 50.6 0.0 4.6e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFM66411.1 - 6.4e-07 29.4 0.0 1.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KFM66411.1 - 0.00047 20.2 0.0 0.00092 19.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KFM66411.1 - 0.013 15.7 0.0 0.19 11.9 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM66411.1 - 0.15 11.7 0.0 0.54 9.8 0.0 1.9 1 1 0 1 1 1 0 Ras family Metallopep PF12044.8 KFM66412.1 - 4.3e-27 94.8 0.0 4.7e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Metallopep PF12044.8 KFM66413.1 - 1.5e-43 149.0 0.1 2.3e-43 148.4 0.1 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 KFM66413.1 - 0.0064 17.0 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM66413.1 - 0.034 14.3 0.7 0.053 13.7 0.1 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12 Kinesin PF00225.23 KFM66414.1 - 2e-12 46.7 0.0 2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM66414.1 - 5.7e-10 39.3 0.0 6.6e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding DDE_1 PF03184.19 KFM66415.1 - 4.1e-09 36.3 0.6 4.5e-09 36.2 0.6 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Ski_Sno PF02437.17 KFM66416.1 - 0.013 15.2 0.1 0.044 13.5 0.1 1.9 2 0 0 2 2 2 0 SKI/SNO/DAC family RRM_5 PF13893.6 KFM66418.1 - 1.4e-46 157.1 1.0 1.1e-35 121.9 0.0 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFM66418.1 - 1.7e-27 95.0 0.4 1.2e-07 31.5 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFM66418.1 - 1.8e-12 47.3 0.2 1.3e-11 44.5 0.1 2.5 3 0 0 3 3 3 1 RRM-like domain RRM_occluded PF16842.5 KFM66418.1 - 2.9e-05 23.8 0.0 4.8 7.1 0.0 4.4 4 0 0 4 4 4 2 Occluded RNA-recognition motif Aminotran_1_2 PF00155.21 KFM66419.1 - 4e-64 217.1 0.0 4.7e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFM66419.1 - 9e-06 24.9 0.0 2.8e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFM66419.1 - 0.0003 20.2 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KFM66419.1 - 0.0044 16.3 0.0 0.0087 15.4 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KFM66419.1 - 0.0083 14.7 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ADH_N PF08240.12 KFM66420.1 - 5.4e-07 29.5 0.0 7.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SH2_2 PF14633.6 KFM66420.1 - 0.17 11.2 0.0 0.2 11.0 0.0 1.0 1 0 0 1 1 1 0 SH2 domain HTH_Tnp_Tc3_2 PF01498.18 KFM66421.1 - 2e-19 69.6 3.6 5.1e-19 68.3 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66421.1 - 3.9e-16 59.1 0.0 2e-15 56.8 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM66421.1 - 3.2e-07 30.9 2.0 3.2e-07 30.9 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KFM66421.1 - 7.4e-07 29.1 0.5 0.00043 20.3 0.0 2.7 3 0 0 3 3 2 2 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM66421.1 - 1.4e-06 28.3 1.1 0.00029 20.9 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM66421.1 - 4.5e-06 26.6 0.3 9.1e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KFM66421.1 - 7.3e-06 25.6 1.9 0.0003 20.5 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM66421.1 - 0.00013 21.7 0.5 0.0023 17.8 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM66421.1 - 0.00099 19.0 0.4 0.015 15.2 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 KFM66421.1 - 0.027 14.5 0.0 6.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain GntR PF00392.21 KFM66421.1 - 0.036 13.7 0.1 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_17 PF12728.7 KFM66421.1 - 0.08 13.1 0.1 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM66421.1 - 0.13 11.8 0.2 0.72 9.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM66421.1 - 0.16 12.1 0.0 27 4.9 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM66421.1 - 0.23 11.3 3.9 1.3 8.8 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Ank_4 PF13637.6 KFM66423.1 - 3.7e-20 72.0 0.9 7.6e-16 58.3 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM66423.1 - 5.3e-18 65.4 0.4 1.1e-17 64.4 0.4 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM66423.1 - 3e-15 55.9 0.1 2.7e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFM66423.1 - 7.2e-15 53.6 0.3 1e-05 25.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFM66423.1 - 1.3e-13 50.9 0.5 8.7e-10 38.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 KFM66423.1 - 1.1e-12 47.4 0.5 2.1e-12 46.4 0.5 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM66423.1 - 5.5e-09 35.8 0.4 1.3e-08 34.5 0.4 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM66423.1 - 5.9e-08 32.3 0.0 4.1e-07 29.6 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain Spc7 PF08317.11 KFM66423.1 - 4.3 6.1 29.4 1.2 8.0 7.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KFM66423.1 - 7.2 7.0 12.4 13 6.2 1.4 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0242 PF06785.11 KFM66423.1 - 9.9 6.2 29.7 54 3.8 28.8 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus VHS PF00790.19 KFM66424.1 - 5.5e-38 130.0 0.2 1.5e-37 128.6 0.0 1.8 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 KFM66424.1 - 1.2e-16 60.0 0.1 2.6e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM66424.1 - 6.6e-13 48.3 0.0 1.9e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM66424.1 - 1.1e-12 47.4 0.0 2.1e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 KFM66424.1 - 0.00052 19.7 1.3 0.00052 19.7 1.3 2.1 2 0 0 2 2 2 1 Ubiquitin interaction motif SH3_10 PF17902.1 KFM66424.1 - 0.0059 16.7 0.0 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 SH3 domain GAT PF03127.14 KFM66424.1 - 0.04 14.2 5.4 0.17 12.2 1.0 3.2 3 0 0 3 3 3 0 GAT domain Kazal_2 PF07648.15 KFM66425.1 - 7.3e-10 38.8 3.5 7.3e-10 38.8 3.5 1.9 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM66425.1 - 5.6e-06 26.3 3.1 7.9e-06 25.8 2.6 1.6 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain I-set PF07679.16 KFM66426.1 - 1.5e-07 31.3 0.0 1.5e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM66426.1 - 4.2e-06 27.3 0.0 4.5e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM66426.1 - 0.00037 20.6 0.0 0.00037 20.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM66426.1 - 0.00065 20.0 0.0 0.00072 19.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM66426.1 - 0.0011 19.2 0.0 0.0011 19.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM66426.1 - 0.0019 17.7 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain PepSY_2 PF13670.6 KFM66426.1 - 0.041 13.9 0.1 0.045 13.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain HTH_Tnp_Tc3_2 PF01498.18 KFM66427.1 - 4.4e-16 58.9 3.5 5.6e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66427.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66427.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66427.1 - 0.0025 17.6 0.6 0.0074 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain DUF812 PF05667.11 KFM66428.1 - 1.6e-190 635.0 23.1 2.1e-190 634.6 23.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Leucyl-specific PF14795.6 KFM66428.1 - 0.58 10.3 3.9 0.24 11.5 0.9 2.0 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain UPF0184 PF03670.13 KFM66428.1 - 5.1 7.6 7.4 50 4.4 2.5 3.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Peptidase_M41 PF01434.18 KFM66429.1 - 2.6e-63 213.4 0.1 4.5e-63 212.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFM66429.1 - 1.6e-39 135.4 0.0 3.2e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM66429.1 - 3.6e-15 55.5 0.0 1.1e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_17 PF13207.6 KFM66429.1 - 2.1e-06 28.2 0.9 8.6e-05 23.0 0.1 3.2 3 1 1 4 4 4 1 AAA domain AAA_5 PF07728.14 KFM66429.1 - 3.5e-06 27.1 0.2 1.5e-05 25.0 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFM66429.1 - 4.6e-06 26.9 0.1 1.9e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFM66429.1 - 4.7e-05 23.7 0.1 0.025 14.9 0.0 3.9 3 1 2 5 5 5 1 AAA domain RuvB_N PF05496.12 KFM66429.1 - 4.8e-05 23.2 0.4 0.00024 20.9 0.0 2.3 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFM66429.1 - 0.00014 21.2 0.1 0.0003 20.1 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KFM66429.1 - 0.00037 20.9 0.1 0.001 19.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KFM66429.1 - 0.0015 18.0 0.1 0.0033 16.8 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KFM66429.1 - 0.0039 17.1 0.1 0.0081 16.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.17 KFM66429.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFM66429.1 - 0.0044 17.6 0.2 0.059 13.9 0.1 2.8 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KFM66429.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM66429.1 - 0.052 13.7 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KFM66429.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KFM66429.1 - 0.063 12.5 0.1 0.16 11.2 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KFM66429.1 - 0.066 13.7 0.1 0.25 11.9 0.1 2.0 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KFM66429.1 - 0.076 13.4 0.0 0.3 11.5 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KFM66429.1 - 0.12 12.1 0.9 9.5 5.9 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KFM66429.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFM66429.1 - 0.17 11.5 0.0 0.45 10.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsH_ext PF06480.15 KFM66430.1 - 0.00011 22.5 0.2 0.00018 21.8 0.0 1.6 2 0 0 2 2 2 1 FtsH Extracellular DNA_pol3_a_NI PF14480.6 KFM66430.1 - 0.098 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I GNT-I PF03071.15 KFM66432.1 - 1.8e-154 514.7 0.3 2.1e-154 514.5 0.3 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 KFM66432.1 - 0.0016 18.4 0.0 0.02 14.8 0.0 2.7 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Peptidase_S66C PF17676.1 KFM66432.1 - 0.077 13.5 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain LRR_8 PF13855.6 KFM66434.1 - 2.1e-134 437.4 91.0 4.2e-17 61.7 2.1 15.5 5 4 11 16 16 16 16 Leucine rich repeat LRR_4 PF12799.7 KFM66434.1 - 5.1e-69 227.0 85.1 9e-08 32.3 0.6 17.8 11 4 8 21 21 21 17 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM66434.1 - 3.1e-41 140.3 21.9 3.1e-08 33.6 0.1 7.4 1 1 7 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM66434.1 - 5.6e-25 84.0 58.6 1.1 10.1 0.0 24.7 26 1 0 26 26 26 6 Leucine Rich Repeat LRR_6 PF13516.6 KFM66434.1 - 3.5e-14 51.6 76.6 1.3 9.2 0.2 22.7 24 0 0 24 24 24 8 Leucine Rich repeat LRR_9 PF14580.6 KFM66434.1 - 7.4e-13 48.4 46.7 0.0023 17.5 0.5 9.2 2 2 10 12 12 12 8 Leucine-rich repeat fn3 PF00041.21 KFM66434.1 - 0.0039 17.5 0.0 0.0089 16.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Rib_recp_KP_reg PF05104.12 KFM66435.1 - 0.02 16.0 31.7 0.02 16.0 31.7 5.9 6 1 1 7 7 7 0 Ribosome receptor lysine/proline rich region DUF4834 PF16118.5 KFM66435.1 - 0.07 14.1 0.6 0.07 14.1 0.6 6.9 6 2 1 7 7 7 0 Domain of unknown function (DUF4834) LapA_dom PF06305.11 KFM66435.1 - 0.51 10.2 0.0 0.51 10.2 0.0 6.6 8 1 0 8 8 8 0 Lipopolysaccharide assembly protein A domain YbjQ_1 PF01906.17 KFM66435.1 - 5.4 7.7 11.3 16 6.2 0.1 4.5 4 1 0 4 4 4 0 Putative heavy-metal-binding zf-NOSIP PF15906.5 KFM66436.1 - 6.5e-42 141.6 4.1 8.1e-42 141.3 3.0 1.7 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 KFM66436.1 - 3.1e-09 36.6 13.1 0.00011 21.7 0.0 3.4 2 2 2 4 4 4 2 Rtf2 RING-finger U-box PF04564.15 KFM66436.1 - 4.2e-07 30.0 0.2 0.011 15.9 0.0 3.1 3 0 0 3 3 3 2 U-box domain zf-Nse PF11789.8 KFM66436.1 - 0.00051 19.8 1.8 0.021 14.7 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit MCM3AP_GANP PF16769.5 KFM66436.1 - 0.026 12.8 0.1 0.029 12.6 0.1 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP ATP-synt_E PF05680.12 KFM66436.1 - 0.7 10.3 6.2 1.7 9.1 6.2 1.6 1 0 0 1 1 1 0 ATP synthase E chain CAMSAP_CKK PF08683.11 KFM66438.1 - 1.9e-51 173.2 0.1 3.8e-51 172.2 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CC1 PF17095.5 KFM66438.1 - 7e-21 73.8 4.0 7e-21 73.8 4.0 3.2 2 1 0 2 2 2 1 Spectrin-binding region of Ca2+-Calmodulin CAMSAP_CH PF11971.8 KFM66438.1 - 1.7e-17 63.0 0.1 5.7e-17 61.3 0.1 1.9 1 0 0 1 1 1 1 CAMSAP CH domain YopE PF03545.13 KFM66438.1 - 0.0076 16.4 0.3 0.027 14.7 0.0 2.1 2 0 0 2 2 2 1 Yersinia virulence determinant (YopE) WD40 PF00400.32 KFM66439.1 - 3.7e-18 65.5 8.1 0.0004 21.1 0.1 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM66439.1 - 4.2e-09 36.6 0.0 0.0045 17.3 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HTH_Tnp_Tc3_2 PF01498.18 KFM66440.1 - 2.2e-16 59.9 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66440.1 - 1.5e-12 47.5 0.0 2.4e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CRAL_TRIO PF00650.20 KFM66442.1 - 0.00012 21.9 0.3 0.00049 19.8 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM66442.1 - 0.00019 21.9 0.0 0.0012 19.3 0.0 1.9 1 1 1 2 2 2 1 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 KFM66443.1 - 0.018 15.2 0.4 0.031 14.5 0.4 1.4 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain SesA PF17107.5 KFM66443.1 - 0.085 13.0 0.2 0.11 12.7 0.2 1.1 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases LRR_8 PF13855.6 KFM66444.1 - 2.5e-17 62.4 9.9 8.9e-08 31.8 1.9 4.4 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFM66444.1 - 3.4e-11 43.2 14.6 0.00029 21.2 5.2 4.7 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM66444.1 - 7.6e-07 29.1 1.9 0.00022 21.2 0.2 2.8 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM66444.1 - 0.00061 19.3 1.0 0.088 12.3 0.3 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFM66444.1 - 2.4 9.1 15.9 14 6.7 0.0 6.4 7 0 0 7 7 7 0 Leucine Rich Repeat Tudor_3 PF18115.1 KFM66445.1 - 6.3e-05 22.7 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KFM66445.1 - 0.0062 16.6 0.0 0.029 14.4 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) PGM_PMM_I PF02878.16 KFM66447.1 - 2e-37 128.0 0.1 3.6e-37 127.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KFM66447.1 - 9.9e-27 93.4 0.0 2.2e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFM66447.1 - 8.7e-19 68.1 0.1 1.7e-17 63.9 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KFM66447.1 - 9e-07 29.0 0.0 2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ribosomal_L12 PF00542.19 KFM66448.1 - 5.4e-20 71.5 7.2 5.4e-20 71.5 7.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KFM66448.1 - 1.5e-13 50.2 3.1 1e-11 44.4 0.8 2.5 2 0 0 2 2 2 2 Ribosomal protein L7/L12 dimerisation domain DUF530 PF04409.12 KFM66448.1 - 0.0072 14.7 1.3 0.012 14.0 1.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF530) DUF4479 PF14794.6 KFM66448.1 - 0.02 14.8 2.8 0.047 13.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) CSTF2_hinge PF14327.6 KFM66448.1 - 0.035 14.5 0.1 2.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 DDE_3 PF13358.6 KFM66449.1 - 7.7e-13 48.4 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66449.1 - 1.2e-12 47.9 1.0 2.4e-12 46.9 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM66450.1 - 4.5e-16 58.8 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66450.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66450.1 - 2e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66450.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66450.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain 7tm_1 PF00001.21 KFM66451.1 - 1.4e-13 50.8 1.1 1.4e-13 50.8 1.1 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM66451.1 - 0.00092 18.7 0.4 0.0013 18.2 0.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Collectrin PF16959.5 KFM66451.1 - 0.62 9.8 3.0 0.77 9.5 1.2 1.8 2 0 0 2 2 2 0 Renal amino acid transporter P16-Arc PF04699.14 KFM66452.1 - 1.7e-51 174.6 0.0 2e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KFM66452.1 - 0.0095 16.2 0.0 0.02 15.2 0.0 1.5 2 0 0 2 2 2 1 Dip2/Utp12 Family Utp13 PF08625.11 KFM66452.1 - 0.089 12.7 0.3 0.16 11.9 0.3 1.4 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain IMD PF08397.11 KFM66453.1 - 7.8e-16 58.1 7.1 1e-15 57.8 7.1 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_1 PF00018.28 KFM66453.1 - 4e-12 45.5 0.0 6.7e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM66453.1 - 1.1e-09 37.9 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM66453.1 - 5e-09 35.7 0.0 9.2e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WH2 PF02205.20 KFM66454.1 - 0.0065 16.3 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 WH2 motif RNA_pol_Rpb1_R PF05001.13 KFM66454.1 - 0.0066 16.8 1.1 0.014 15.8 1.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1 C-terminal repeat SAM_1 PF00536.30 KFM66455.1 - 1.2e-09 38.5 0.0 2.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM66455.1 - 3.4e-06 27.1 0.0 7.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FliJ PF02050.16 KFM66455.1 - 0.45 10.8 13.4 0.96 9.7 11.9 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein Snf7 PF03357.21 KFM66455.1 - 8 6.0 16.6 0.18 11.4 8.6 2.2 2 0 0 2 2 2 0 Snf7 VGLL4 PF15245.6 KFM66456.1 - 3.9e-17 63.1 11.6 5.1e-08 33.3 0.1 2.9 2 1 1 3 3 3 2 Transcription cofactor vestigial-like protein 4 Vg_Tdu PF07545.14 KFM66456.1 - 3.5e-05 23.4 0.1 0.073 12.9 0.0 2.4 2 0 0 2 2 2 2 Vestigial/Tondu family GDA1_CD39 PF01150.17 KFM66458.1 - 2.2e-76 257.2 4.4 3.8e-76 256.4 4.4 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Rad60-SLD PF11976.8 KFM66458.1 - 0.001 18.9 0.0 0.003 17.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ephrin PF00812.17 KFM66458.1 - 0.12 12.3 3.8 0.23 11.5 3.8 1.4 1 0 0 1 1 1 0 Ephrin ERK-JNK_inhib PF15002.6 KFM66461.1 - 3.4e-53 180.3 0.3 4.1e-53 180.0 0.3 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor Integrase_H2C2 PF17921.1 KFM66463.1 - 2.5e-19 69.1 0.1 3.7e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM66463.1 - 2e-05 24.7 0.0 4.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 KFM66463.1 - 0.001 19.2 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain SH2 PF00017.24 KFM66464.1 - 1.2e-06 28.5 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 KFM66464.1 - 0.0006 19.3 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 SH2 domain DDE_3 PF13358.6 KFM66465.1 - 5.1e-07 29.6 0.2 2.9e-05 23.9 0.2 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM66466.1 - 3.6e-11 43.0 0.0 5.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66466.1 - 4.3e-07 30.1 0.2 8.5e-07 29.1 0.2 1.4 1 0 0 1 1 1 1 Transposase LRR_8 PF13855.6 KFM66468.1 - 1.5e-106 348.1 162.2 1.5e-16 59.9 4.5 14.0 4 4 11 15 15 15 15 Leucine rich repeat LRR_4 PF12799.7 KFM66468.1 - 5.1e-46 153.9 117.9 2e-06 28.0 3.0 16.3 8 3 9 17 17 17 15 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM66468.1 - 5.8e-44 149.1 29.9 7.3e-11 42.1 4.4 6.6 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM66468.1 - 7.5e-15 54.9 48.4 1.7e-05 24.4 2.2 8.1 2 2 6 8 8 8 5 Leucine-rich repeat TIR PF01582.20 KFM66468.1 - 1.3e-14 54.4 0.4 4.5e-14 52.6 0.4 2.0 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFM66468.1 - 4e-11 43.6 0.1 1.2e-10 42.0 0.1 1.9 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 KFM66468.1 - 1.6e-10 40.0 110.5 0.29 11.8 1.3 23.2 25 1 1 26 26 26 9 Leucine Rich Repeat TGF_beta PF00019.20 KFM66469.1 - 4.9e-36 123.9 0.2 9.4e-36 123.0 0.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFM66469.1 - 3.9e-23 82.5 1.3 3.7e-22 79.3 0.2 2.0 2 0 0 2 2 2 1 TGF-beta propeptide CLIP PF12032.8 KFM66472.1 - 0.00046 20.4 2.9 0.0028 17.9 1.0 2.7 2 1 0 2 2 2 1 Regulatory CLIP domain of proteinases FXa_inhibition PF14670.6 KFM66473.1 - 2.5e-10 40.4 10.6 2.5e-10 40.4 10.6 3.0 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFM66473.1 - 2.3e-09 37.3 9.6 2.3e-09 37.3 9.6 3.2 3 1 0 3 3 3 1 Calcium-binding EGF domain cEGF PF12662.7 KFM66473.1 - 1.8e-07 30.9 8.9 8.7e-07 28.8 4.4 3.7 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.27 KFM66473.1 - 5e-05 23.5 28.5 0.00038 20.7 5.9 2.7 3 0 0 3 3 2 2 EGF-like domain FlxA PF14282.6 KFM66473.1 - 0.0047 16.9 0.2 0.0079 16.2 0.2 1.3 1 0 0 1 1 1 1 FlxA-like protein Plasmod_Pvs28 PF06247.11 KFM66473.1 - 0.0058 16.9 6.6 0.0058 16.9 6.6 3.5 3 1 0 3 3 2 1 Pvs28 EGF domain EGF_2 PF07974.13 KFM66473.1 - 0.0059 16.9 12.7 0.0059 16.9 12.7 3.2 3 0 0 3 3 3 1 EGF-like domain EGF_3 PF12947.7 KFM66473.1 - 0.0065 16.6 8.9 0.0065 16.6 8.9 3.4 3 1 0 3 3 2 1 EGF domain Ead_Ea22 PF13935.6 KFM66473.1 - 0.039 14.6 0.1 0.049 14.3 0.1 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein hEGF PF12661.7 KFM66473.1 - 0.041 14.5 3.8 0.041 14.5 3.8 3.8 4 1 0 4 4 3 0 Human growth factor-like EGF Csm1_N PF18504.1 KFM66473.1 - 0.097 13.0 2.8 0.73 10.2 0.2 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain ABC_tran_CTD PF16326.5 KFM66473.1 - 0.12 12.6 4.4 1.5 9.1 0.3 2.2 1 1 0 1 1 1 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 KFM66473.1 - 0.2 11.9 2.0 2.1 8.6 0.6 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PspB PF06667.12 KFM66473.1 - 0.83 9.8 3.8 0.72 9.9 0.3 2.0 1 1 1 2 2 2 0 Phage shock protein B BTB PF00651.31 KFM66474.1 - 6.6e-06 26.3 0.1 8.5e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFM66475.1 - 1.4e-14 54.3 0.5 1.5e-14 54.2 0.5 1.0 1 0 0 1 1 1 1 BTB/POZ domain hnRNP_Q_AcD PF18360.1 KFM66475.1 - 0.038 14.0 0.2 0.42 10.6 0.1 2.1 1 1 1 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Kelch_1 PF01344.25 KFM66476.1 - 7.3e-13 47.9 0.4 1e-12 47.5 0.0 1.5 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 KFM66476.1 - 1.4e-05 25.2 0.0 1.7e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM66476.1 - 0.00013 22.1 0.0 0.00018 21.7 0.0 1.2 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 KFM66476.1 - 0.0026 17.7 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_2 PF07646.15 KFM66476.1 - 0.027 14.4 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Kelch motif HTH_Tnp_Tc3_2 PF01498.18 KFM66477.1 - 2.5e-16 59.7 2.2 6.7e-16 58.3 2.2 1.8 1 0 0 1 1 1 1 Transposase Kelch_1 PF01344.25 KFM66477.1 - 2.7e-15 55.7 0.1 6e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 Kelch motif DDE_3 PF13358.6 KFM66477.1 - 1.6e-13 50.7 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Kelch_6 PF13964.6 KFM66477.1 - 7.1e-09 35.6 0.0 2e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Kelch motif HTH_38 PF13936.6 KFM66477.1 - 3.5e-07 29.9 1.6 8e-07 28.7 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Kelch_2 PF07646.15 KFM66477.1 - 0.00012 21.9 0.1 0.00051 19.9 0.0 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 KFM66477.1 - 0.00084 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain HTH_23 PF13384.6 KFM66477.1 - 0.0031 17.2 0.5 0.0087 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Kelch_3 PF13415.6 KFM66477.1 - 0.0032 17.7 0.3 0.0095 16.2 0.3 1.8 1 0 0 1 1 1 1 Galactose oxidase, central domain HTH_32 PF13565.6 KFM66477.1 - 3.4 8.4 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Gp_dh_N PF00044.24 KFM66480.1 - 1.9e-38 130.9 0.2 2.9e-38 130.3 0.2 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KFM66480.1 - 7.9e-37 126.3 0.3 1.1e-36 125.8 0.3 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 KFM66480.1 - 0.001 18.5 0.2 0.0018 17.7 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mito_carr PF00153.27 KFM66481.1 - 3.3e-33 113.5 0.2 1.4e-15 57.0 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein EutK_C PF16365.5 KFM66481.1 - 0.15 12.1 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus MBOAT PF03062.19 KFM66482.1 - 1.7e-28 100.0 32.2 2.5e-28 99.4 32.2 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KFM66482.1 - 0.001 19.3 2.7 0.0042 17.3 2.7 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CPP1-like PF11833.8 KFM66482.1 - 0.02 14.6 0.9 0.02 14.6 0.9 2.3 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DDE_3 PF13358.6 KFM66484.1 - 0.016 15.0 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Gemini_mov PF01708.16 KFM66486.1 - 2 8.2 6.4 2.1 8.2 0.9 2.3 2 0 0 2 2 2 0 Geminivirus putative movement protein Trypsin PF00089.26 KFM66487.1 - 1.7e-53 181.7 0.0 2.3e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KFM66488.1 - 2.1e-32 112.8 0.0 2.3e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Meckelin PF09773.9 KFM66489.1 - 1.1e-34 119.7 4.4 1.1e-34 119.7 4.4 1.6 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) Tnp_zf-ribbon_2 PF13842.6 KFM66489.1 - 0.13 13.1 0.3 0.13 13.1 0.3 4.7 4 1 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon Ephrin_rec_like PF07699.13 KFM66489.1 - 1.3 8.9 32.3 0.084 12.7 5.5 4.9 1 1 4 5 5 5 0 Putative ephrin-receptor like Meckelin PF09773.9 KFM66490.1 - 3.3e-18 65.2 0.0 3.6e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Meckelin PF09773.9 KFM66491.1 - 5.2e-129 431.7 8.0 6.3e-129 431.5 8.0 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) AA_permease_2 PF13520.6 KFM66493.1 - 2.2e-49 168.4 43.9 2.7e-49 168.1 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM66493.1 - 3.8e-20 71.9 42.8 8.2e-20 70.8 42.8 1.6 1 1 0 1 1 1 1 Amino acid permease SBF2 PF12335.8 KFM66494.1 - 6.7e-08 32.4 0.2 6.7e-08 32.4 0.2 2.1 2 1 0 2 2 2 1 Myotubularin protein PA26 PF04636.13 KFM66494.1 - 0.0039 16.2 4.2 0.0054 15.7 4.2 1.2 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Metallophos PF00149.28 KFM66495.1 - 1.9e-14 54.7 0.3 3.1e-14 54.0 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM66495.1 - 0.00012 22.3 0.2 0.0014 18.8 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1796 PF08795.10 KFM66495.1 - 0.16 12.0 1.8 0.3 11.0 0.6 1.9 2 1 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) T-box PF00907.22 KFM66496.1 - 8.5e-63 211.9 0.1 1.3e-62 211.4 0.1 1.3 1 0 0 1 1 1 1 T-box HTH_Tnp_Tc3_2 PF01498.18 KFM66497.1 - 5.5e-16 58.6 2.2 5.5e-16 58.6 2.2 2.2 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM66497.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66497.1 - 1.9e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66497.1 - 0.0024 17.6 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66497.1 - 0.027 14.6 0.4 0.088 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM66497.1 - 2 9.1 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain T-box PF00907.22 KFM66498.1 - 8.6e-80 267.3 0.0 1.7e-79 266.4 0.0 1.5 1 0 0 1 1 1 1 T-box DDE_3 PF13358.6 KFM66499.1 - 1.1e-16 60.8 0.1 1.3e-15 57.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66499.1 - 7.4e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM66499.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM66499.1 - 0.0023 17.7 0.1 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66499.1 - 0.014 15.5 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM66499.1 - 0.034 14.2 2.6 0.034 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM66501.1 - 3.2e-06 27.0 0.1 4.7e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66502.1 - 3.4e-16 59.2 3.0 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66502.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66502.1 - 6e-05 22.7 1.1 0.00027 20.7 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM66502.1 - 3.1 8.5 14.7 0.2 12.3 1.4 3.1 2 1 1 3 3 3 0 Homeodomain-like domain MLVIN_C PF18697.1 KFM66503.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain SpmSyn_N PF17950.1 KFM66504.1 - 0.082 13.1 0.3 0.21 11.8 0.1 1.8 1 1 1 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal DUF2757 PF10955.8 KFM66504.1 - 0.12 12.7 1.8 0.21 11.9 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) DDE_1 PF03184.19 KFM66505.1 - 0.12 12.0 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Forkhead PF00250.18 KFM66506.1 - 1.1e-34 118.5 0.0 2.4e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain GAGA_bind PF06217.12 KFM66506.1 - 0.048 13.9 2.4 0.083 13.2 2.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2393 PF09624.10 KFM66506.1 - 0.14 12.1 0.7 0.32 11.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) Forkhead PF00250.18 KFM66507.1 - 3.6e-40 136.1 0.0 7e-40 135.2 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain DDE_3 PF13358.6 KFM66508.1 - 4.7e-14 52.4 0.0 1.3e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66508.1 - 2.8e-08 33.9 2.5 5.9e-08 32.8 2.5 1.6 1 0 0 1 1 1 1 Transposase ecTbetaR2 PF08917.10 KFM66508.1 - 0.011 15.6 0.0 0.011 15.6 0.0 1.7 2 0 0 2 2 2 0 Transforming growth factor beta receptor 2 ectodomain HTH_Tnp_Tc3_2 PF01498.18 KFM66510.1 - 1.4e-13 50.9 0.4 2.4e-13 50.1 0.4 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM66510.1 - 0.0026 18.3 3.4 0.025 15.2 0.7 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM66510.1 - 0.038 14.0 0.2 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix MarR_2 PF12802.7 KFM66510.1 - 0.084 12.8 0.3 1.2 9.1 0.0 2.4 2 1 0 2 2 2 0 MarR family CNOT11 PF10155.9 KFM66511.1 - 5e-28 97.8 2.9 5.5e-28 97.6 2.9 1.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Pol_alpha_B_N PF08418.10 KFM66511.1 - 0.19 11.7 0.1 0.26 11.2 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ribosomal_S28e PF01200.18 KFM66513.1 - 1.7e-34 117.6 1.2 1.8e-34 117.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e CI-B14_5a PF07347.12 KFM66514.1 - 8.4e-31 105.7 0.0 9.6e-31 105.5 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Aminotran_1_2 PF00155.21 KFM66518.1 - 0.0059 15.8 0.0 0.0064 15.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFM66518.1 - 0.054 12.5 0.0 0.063 12.2 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class-V KxDL PF10241.9 KFM66520.1 - 0.0093 16.2 0.1 0.014 15.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Trigger_C PF05698.14 KFM66521.1 - 0.021 14.9 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Phage_prot_Gp6 PF05133.14 KFM66521.1 - 0.041 13.0 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like Alpha_E3_glycop PF01563.16 KFM66521.1 - 0.16 12.0 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein LSDAT_euk PF18139.1 KFM66522.1 - 0.0022 17.4 0.1 0.004 16.6 0.0 1.4 2 0 0 2 2 2 1 SLOG in TRPM Ski2_N PF17911.1 KFM66524.1 - 1.6e-22 79.8 0.0 4.1e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 KFM66524.1 - 1.6e-18 67.1 0.6 1.2e-17 64.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 KFM66524.1 - 1.7e-09 38.0 3.8 1.7e-09 38.0 3.8 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain Helicase_C PF00271.31 KFM66524.1 - 4e-08 33.6 0.1 1.2e-07 32.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM66524.1 - 3.6e-07 30.3 0.5 2.1e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3516 PF12029.8 KFM66524.1 - 0.02 14.0 0.1 0.036 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Sp38 PF07354.12 KFM66524.1 - 0.025 14.0 2.0 0.03 13.8 0.1 2.0 3 0 0 3 3 3 0 Zona-pellucida-binding protein (Sp38) PhoH PF02562.16 KFM66524.1 - 0.037 13.5 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 KFM66524.1 - 0.075 13.3 0.1 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Holin_BhlA PF10960.8 KFM66524.1 - 0.19 11.7 4.7 0.25 11.3 0.1 3.2 3 1 0 3 3 3 0 BhlA holin family DSHCT PF08148.12 KFM66525.1 - 2.8e-46 157.2 0.5 3.3e-46 156.9 0.5 1.0 1 0 0 1 1 1 1 DSHCT (NUC185) domain Collagen PF01391.18 KFM66526.1 - 2.4e-12 46.4 45.6 1.1e-07 31.5 21.1 2.7 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) VWC PF00093.18 KFM66526.1 - 1e-10 41.8 14.9 1.3e-10 41.4 14.9 1.2 1 0 0 1 1 1 1 von Willebrand factor type C domain OGFr_III PF04680.13 KFM66526.1 - 0.033 14.8 2.9 0.033 14.8 2.9 2.9 2 0 0 2 2 2 0 Opioid growth factor receptor repeat Amnionless PF14828.6 KFM66526.1 - 0.93 8.2 12.4 1.2 7.8 12.4 1.1 1 0 0 1 1 1 0 Amnionless Collagen PF01391.18 KFM66527.1 - 1.5e-33 114.3 100.9 7.6e-10 38.4 25.4 4.0 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) Collagen PF01391.18 KFM66528.1 - 6.3e-115 375.0 422.3 4.1e-09 36.1 24.2 13.8 1 1 7 8 8 8 5 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFM66528.1 - 7.7e-76 254.5 0.1 9.6e-76 254.1 0.1 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain ABC_tran_CTD PF16326.5 KFM66532.1 - 0.0023 18.2 0.2 0.0031 17.7 0.2 1.1 1 0 0 1 1 1 1 ABC transporter C-terminal domain GCHY-1 PF02649.14 KFM66532.1 - 0.03 13.9 0.0 0.03 13.9 0.0 1.0 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 zinc_ribbon_10 PF10058.9 KFM66534.1 - 5.4e-13 48.5 0.7 7.1e-13 48.1 0.7 1.2 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_SprT PF17283.2 KFM66534.1 - 0.19 11.7 3.6 5.5 7.0 1.8 2.4 1 1 1 2 2 2 0 SprT-like zinc ribbon domain PAF PF15715.5 KFM66535.1 - 4.8e-36 124.3 2.8 5.4e-36 124.2 2.8 1.0 1 0 0 1 1 1 1 PCNA-associated factor histone like domain ADH_zinc_N_2 PF13602.6 KFM66537.1 - 1.2e-13 52.2 0.0 2e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM66537.1 - 5e-09 36.0 0.1 5.2e-07 29.5 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM66537.1 - 7.7e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase_Tyr PF07714.17 KFM66538.1 - 1.3e-98 329.4 0.0 1.7e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM66538.1 - 6.6e-50 169.9 0.0 9.1e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFM66538.1 - 9.5e-27 92.9 0.4 2.4e-26 91.6 0.3 1.7 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.28 KFM66538.1 - 9.5e-19 66.8 0.3 2.8e-18 65.3 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFM66538.1 - 5.7e-12 45.3 0.1 2e-11 43.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFM66538.1 - 9.1e-11 41.3 0.0 1.6e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 KFM66538.1 - 0.00032 19.7 0.0 0.00069 18.7 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM66538.1 - 0.033 14.1 0.0 0.17 11.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM66538.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family hSH3 PF14603.6 KFM66538.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Helically-extended SH3 domain Neurensin PF14927.6 KFM66539.1 - 5.8e-28 97.2 0.1 8.6e-28 96.7 0.1 1.2 1 0 0 1 1 1 1 Neurensin DUF3784 PF12650.7 KFM66539.1 - 0.2 11.9 5.8 4.8 7.4 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) TMEM234 PF10639.9 KFM66541.1 - 4.2e-40 136.4 1.6 4.9e-40 136.2 1.6 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KFM66541.1 - 0.14 12.3 11.7 0.37 11.0 1.5 2.1 1 1 1 2 2 2 0 EamA-like transporter family RPEL PF02755.15 KFM66542.1 - 1.6e-32 110.2 16.9 9.8e-08 31.5 0.1 4.8 4 0 0 4 4 4 4 RPEL repeat GRAM PF02893.20 KFM66542.1 - 0.0011 18.8 0.0 0.0036 17.2 0.0 1.8 1 0 0 1 1 1 1 GRAM domain LLGL PF08366.13 KFM66543.1 - 5.8e-33 113.3 0.0 1.5e-32 112.0 0.0 1.7 1 0 0 1 1 1 1 LLGL2 Lgl_C PF08596.10 KFM66543.1 - 2.5e-11 42.9 2.2 2.8e-06 26.3 0.1 3.5 3 1 1 4 4 4 2 Lethal giant larvae(Lgl) like, C-terminal Synaptobrevin PF00957.21 KFM66543.1 - 4.9e-07 29.5 1.7 1.2e-06 28.2 1.7 1.7 1 0 0 1 1 1 1 Synaptobrevin WD40 PF00400.32 KFM66543.1 - 0.061 14.2 3.9 1.6 9.7 0.6 4.4 3 1 0 3 3 3 0 WD domain, G-beta repeat RmuC PF02646.16 KFM66543.1 - 0.07 12.3 1.7 0.13 11.4 1.7 1.3 1 0 0 1 1 1 0 RmuC family DUF4201 PF13870.6 KFM66543.1 - 0.27 11.0 2.6 0.61 9.8 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) ANAPC4_WD40 PF12894.7 KFM66544.1 - 0.0045 17.2 0.0 0.019 15.3 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM66544.1 - 0.13 13.2 0.0 12 7.0 0.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Neur_chan_memb PF02932.16 KFM66545.1 - 6.1e-12 46.1 3.1 2.5e-08 34.3 3.1 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4199 PF13858.6 KFM66545.1 - 0.095 13.1 0.1 0.095 13.1 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Neur_chan_LBD PF02931.23 KFM66546.1 - 4.8e-47 160.2 0.1 5.7e-47 159.9 0.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM66547.1 - 4.5e-38 131.7 0.1 5.7e-38 131.3 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM66547.1 - 1.8e-37 128.9 0.2 3.2e-37 128.1 0.2 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFM66550.1 - 4.2e-42 144.0 0.0 6.2e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM66550.1 - 2.9e-41 142.1 2.3 2.8e-35 122.5 0.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Histidinol_dh PF00815.20 KFM66550.1 - 0.057 12.4 0.1 8 5.3 0.0 2.1 2 0 0 2 2 2 0 Histidinol dehydrogenase HTH_Tnp_Tc3_2 PF01498.18 KFM66551.1 - 2.6e-16 59.6 2.2 4.7e-16 58.8 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66551.1 - 1.1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Lig_chan PF00060.26 KFM66553.1 - 1.7e-52 177.2 0.7 2.1e-52 176.9 0.7 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Ion_trans_2 PF07885.16 KFM66553.1 - 6.6 6.8 9.4 3.7 7.6 2.0 2.6 1 1 0 2 2 2 0 Ion channel Frag1 PF10277.9 KFM66554.1 - 4e-08 33.0 28.3 1.6e-07 31.1 28.3 2.0 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family Pox_I5 PF04713.12 KFM66554.1 - 0.018 15.1 1.4 0.018 15.1 1.4 2.8 3 1 0 3 3 3 0 Poxvirus protein I5 Frag1 PF10277.9 KFM66555.1 - 7.1e-17 61.7 6.8 1.1e-16 61.0 6.8 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MIG-14_Wnt-bd PF06664.12 KFM66555.1 - 0.73 9.0 8.3 1.2 8.3 4.3 2.3 1 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion HTH_Tnp_Tc3_2 PF01498.18 KFM66557.1 - 2.4e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66557.1 - 9.6e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Rhomboid PF01694.22 KFM66560.1 - 1.6e-29 102.8 11.6 1.6e-29 102.8 11.6 1.6 2 0 0 2 2 2 1 Rhomboid family 5_nucleotid PF05761.14 KFM66561.1 - 9.9e-62 209.3 0.6 1e-61 209.2 0.6 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KFM66561.1 - 0.0016 18.5 0.0 0.0059 16.7 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM66561.1 - 0.084 13.1 0.0 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HTH_Tnp_Tc3_2 PF01498.18 KFM66562.1 - 2.2e-16 59.8 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66562.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Spot_14 PF07084.12 KFM66563.1 - 1.5e-33 116.1 0.1 4.3e-33 114.6 0.1 1.6 1 1 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 MRP-L28 PF09812.9 KFM66564.1 - 9.6e-12 45.3 5.2 1.1e-11 45.1 5.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF2461 PF09365.10 KFM66564.1 - 0.055 13.4 0.2 0.068 13.1 0.2 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) HTH_Tnp_Tc3_2 PF01498.18 KFM66565.1 - 4.6e-16 58.8 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66565.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66565.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66565.1 - 0.0025 17.6 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66565.1 - 2 9.1 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66566.1 - 2.2e-16 59.9 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66566.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66567.1 - 2e-16 60.0 2.2 6.7e-16 58.3 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66567.1 - 1.6e-13 50.7 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66567.1 - 3.4e-07 29.9 1.6 8e-07 28.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66567.1 - 0.0032 17.2 0.5 0.0087 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66567.1 - 3.2 8.4 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain SHR-BD PF06650.12 KFM66569.1 - 1.1e-39 136.5 0.0 1.1e-37 129.9 0.1 2.3 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 HTH_Tnp_Tc3_2 PF01498.18 KFM66570.1 - 2.2e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66570.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM66572.1 - 4.5e-07 29.7 0.0 9.4e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66574.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66574.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66574.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66574.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66574.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Integrin_b_cyt PF08725.11 KFM66575.1 - 0.052 13.2 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain DDE_3 PF13358.6 KFM66576.1 - 2e-16 60.1 0.1 6.2e-15 55.2 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66576.1 - 6.6e-16 58.3 6.5 1.3e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM66576.1 - 0.00067 20.2 1.5 0.00067 20.2 1.5 2.8 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM66576.1 - 0.0022 17.7 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66576.1 - 0.015 15.4 0.1 0.061 13.5 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM66576.1 - 0.03 14.3 2.6 0.033 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix UCH PF00443.29 KFM66577.1 - 8.3e-38 130.3 1.1 9.3e-38 130.2 1.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM66577.1 - 1.6e-20 73.9 2.9 1.8e-20 73.8 2.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFM66577.1 - 0.0082 15.6 8.3 0.016 14.7 5.7 2.2 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase NapB PF03892.14 KFM66577.1 - 0.54 10.3 6.1 1.1 9.3 6.1 1.5 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) HTH_Tnp_Tc3_2 PF01498.18 KFM66578.1 - 2.7e-16 59.6 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66578.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66578.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66578.1 - 0.0023 17.6 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66578.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ank_2 PF12796.7 KFM66579.1 - 3.8e-08 33.8 0.9 8.1e-08 32.7 0.6 1.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM66579.1 - 1.9e-07 31.5 0.5 7.7e-07 29.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM66579.1 - 8.6e-06 25.7 0.2 3.6e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KFM66579.1 - 2.4e-05 24.6 0.7 5.1e-05 23.5 0.2 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KFM66579.1 - 0.00015 22.0 0.3 0.00031 21.0 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) DUF4588 PF15251.6 KFM66580.1 - 3.1e-57 194.2 1.4 4.2e-57 193.8 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) DUF19 PF01579.18 KFM66580.1 - 0.027 14.3 0.1 0.077 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF19) Myotub-related PF06602.14 KFM66581.1 - 2.9e-132 440.9 0.3 3.5e-132 440.6 0.3 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFM66581.1 - 0.00011 21.9 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM66581.1 - 0.0031 17.3 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM66581.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family 3-PAP PF12578.8 KFM66581.1 - 0.39 10.5 2.3 1.1 9.0 1.7 2.2 2 1 0 2 2 2 0 Myotubularin-associated protein Glyco_transf_7N PF13733.6 KFM66582.1 - 1.1e-58 196.7 0.3 2.9e-58 195.3 0.0 1.8 2 0 0 2 2 2 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFM66582.1 - 3.6e-31 106.6 1.2 6.7e-31 105.8 0.6 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase zf-H2C2_2 PF13465.6 KFM66583.1 - 4.6e-63 207.0 57.1 7.3e-09 35.7 1.2 9.0 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66583.1 - 2.2e-36 122.3 71.1 2.7e-05 24.3 3.6 9.2 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66583.1 - 3.7e-25 86.4 72.8 0.0011 19.6 1.3 9.1 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM66583.1 - 1.3e-17 63.5 69.9 0.0024 18.2 1.3 9.5 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM66583.1 - 3.1e-10 39.6 33.8 0.071 12.9 0.0 7.7 7 0 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM66583.1 - 1.7e-09 37.4 66.1 0.049 13.7 0.9 9.5 9 2 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM66583.1 - 1.1e-08 35.2 48.3 0.24 11.7 0.6 8.9 7 2 1 8 8 8 6 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM66583.1 - 2e-07 30.9 24.7 0.041 13.9 2.6 5.7 4 1 0 5 5 4 3 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM66583.1 - 1.8e-06 28.1 1.1 0.23 11.6 0.0 3.5 1 1 2 3 3 3 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-CHCC PF10276.9 KFM66583.1 - 3.6e-06 26.9 6.9 13 5.9 0.0 7.5 8 0 0 8 8 8 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KFM66583.1 - 0.0001 22.1 33.9 2.8 8.0 0.2 8.9 9 0 0 9 9 9 1 zinc-finger of a C2HC-type FYVE PF01363.21 KFM66583.1 - 0.00016 21.7 46.0 0.35 11.0 9.8 4.6 2 2 1 3 3 3 3 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 KFM66583.1 - 0.00077 19.5 36.5 0.22 11.6 0.8 8.0 6 3 3 9 9 9 4 Sec23/Sec24 zinc finger DUF2256 PF10013.9 KFM66583.1 - 0.011 15.8 31.2 12 6.2 0.1 8.2 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.16 KFM66583.1 - 0.16 11.8 41.2 3.6 7.6 0.9 8.2 8 0 0 8 8 8 0 HIT zinc finger Scramblase PF03803.15 KFM66583.1 - 0.33 10.2 8.5 0.14 11.4 2.3 2.5 1 1 2 3 3 3 0 Scramblase zf-FPG_IleRS PF06827.14 KFM66583.1 - 3.2 7.7 25.0 59 3.7 0.1 8.0 9 0 0 9 9 8 0 Zinc finger found in FPG and IleRS zf_UBZ PF18439.1 KFM66583.1 - 8.1 6.1 35.1 2.6 7.7 0.1 7.9 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger DUF4306 PF14154.6 KFM66584.1 - 0.031 14.4 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Guanylate_cyc PF00211.20 KFM66585.1 - 1.4e-60 204.1 0.0 1.6e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain rve PF00665.26 KFM66588.1 - 0.038 14.2 0.0 0.039 14.1 0.0 1.0 1 0 0 1 1 1 0 Integrase core domain DDE_3 PF13358.6 KFM66589.1 - 8.7e-06 25.6 0.0 7.6e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HHH PF00633.23 KFM66589.1 - 0.09 12.7 0.2 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Rhodopsin_N PF10413.9 KFM66589.1 - 0.11 12.4 0.4 21 5.0 0.1 2.5 2 0 0 2 2 2 0 Amino terminal of the G-protein receptor rhodopsin Ig_3 PF13927.6 KFM66590.1 - 1.4e-31 108.9 0.1 3.7e-17 62.7 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM66590.1 - 4e-31 106.9 0.0 2.8e-15 56.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM66590.1 - 2.8e-26 91.5 0.4 2.6e-14 53.2 0.2 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM66590.1 - 2.2e-15 56.7 0.2 1.2e-09 38.3 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM66590.1 - 7.4e-13 48.6 2.2 2.9e-06 27.4 0.1 3.5 2 2 0 2 2 2 2 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.15 KFM66590.1 - 1.2e-07 31.4 0.4 5.5e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 Adenovirus E3 region protein CR1 Ig_5 PF16681.5 KFM66590.1 - 2.6e-05 24.6 0.2 0.0063 16.9 0.0 2.9 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFM66590.1 - 3.8e-05 24.0 0.2 0.16 12.4 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin C1-set domain C2-set_2 PF08205.12 KFM66590.1 - 0.0012 18.9 0.4 0.0038 17.2 0.2 1.9 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM66590.1 - 0.0016 18.0 0.0 0.51 9.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 KFM66590.1 - 0.0077 16.5 0.4 3.2 8.1 0.1 3.1 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFM66590.1 - 0.018 15.0 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 C17orf99 Ig domain zf-CCHC PF00098.23 KFM66591.1 - 9.1e-06 25.5 1.4 1.4e-05 25.0 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM66591.1 - 0.0036 17.0 0.4 0.0062 16.2 0.4 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM66591.1 - 0.085 12.6 0.7 0.14 11.9 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle VWA_2 PF13519.6 KFM66592.1 - 7.5e-05 23.3 0.0 8.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain INT_SG_DDX_CT_C PF15300.6 KFM66594.1 - 1.1e-08 34.7 0.1 1.9e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus DUF2012 PF09430.10 KFM66595.1 - 1.4e-30 105.9 0.1 2.1e-30 105.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 KFM66595.1 - 0.032 13.8 0.1 0.047 13.2 0.1 1.2 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein CarboxypepD_reg PF13620.6 KFM66595.1 - 0.071 13.4 0.0 0.34 11.2 0.0 1.9 1 1 1 2 2 2 0 Carboxypeptidase regulatory-like domain P53 PF00870.18 KFM66596.1 - 1.3e-54 184.9 0.0 1.7e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 P53 DNA-binding domain TMEM213 PF15192.6 KFM66596.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 TMEM213 family DDE_3 PF13358.6 KFM66598.1 - 2.7e-16 59.6 0.1 3e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66598.1 - 1.3e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase PRCH PF03967.13 KFM66600.1 - 6.8 6.9 7.4 0.7 10.1 0.9 2.0 1 1 1 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region SHMT PF00464.19 KFM66601.1 - 5.6e-64 216.2 0.0 6.2e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DTC PF18102.1 KFM66601.1 - 0.066 13.3 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 Deltex C-terminal domain DUF4371 PF14291.6 KFM66603.1 - 4.2e-06 26.6 0.0 4.2e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM66603.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type DDE_3 PF13358.6 KFM66604.1 - 9.6e-10 38.4 0.1 1.2e-08 34.9 0.1 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Baculo_p33 PF05214.12 KFM66604.1 - 0.014 15.1 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 Baculovirus P33 WH1 PF00568.23 KFM66605.1 - 2.2e-28 98.4 0.1 3.3e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.18 KFM66605.1 - 0.035 14.4 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 RanBP1 domain HTH_Tnp_Tc3_2 PF01498.18 KFM66608.1 - 1.3e-14 54.2 0.9 2.6e-14 53.2 0.9 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM66608.1 - 3.9e-06 27.4 6.9 1.8e-05 25.2 1.8 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM66608.1 - 0.0013 18.7 0.5 0.015 15.2 0.0 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KFM66608.1 - 0.0015 18.4 0.3 0.0036 17.1 0.0 1.8 2 0 0 2 2 2 1 MarR family Defb50 PF17546.2 KFM66608.1 - 0.0036 17.2 0.1 0.0084 16.0 0.1 1.6 1 0 0 1 1 1 1 Beta defensin 50 HTH_24 PF13412.6 KFM66608.1 - 0.073 12.6 0.1 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM66608.1 - 0.099 12.5 1.5 4.6 7.2 0.0 3.2 3 0 0 3 3 3 0 Homeodomain-like domain HTH_3 PF01381.22 KFM66608.1 - 0.14 12.3 0.3 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_Tc3_2 PF01498.18 KFM66609.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66609.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66609.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66609.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66609.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66610.1 - 4.2e-16 59.0 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66610.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66610.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66610.1 - 0.0023 17.6 0.6 0.007 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66610.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Drf_GBD PF06371.13 KFM66611.1 - 3.4e-05 23.5 0.4 5.3e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF5578 PF17741.1 KFM66611.1 - 0.019 14.4 0.1 0.033 13.6 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5578) HTH_Tnp_Tc3_2 PF01498.18 KFM66612.1 - 2e-16 60.0 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66612.1 - 8.2e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4228 PF14009.6 KFM66613.1 - 1.2 9.5 7.9 0.65 10.4 5.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) Neur_chan_memb PF02932.16 KFM66613.1 - 5.4 7.0 4.9 6.1 6.8 4.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MID_MedPIWI PF18296.1 KFM66613.1 - 7.8 6.2 12.0 20 4.9 12.0 1.7 1 1 0 1 1 1 0 MID domain of medPIWI TPR_12 PF13424.6 KFM66614.1 - 1.7e-09 37.8 1.1 4.6e-09 36.4 0.3 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM66614.1 - 1.2e-06 28.1 2.6 2.5e-05 23.9 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFM66614.1 - 2.8e-05 23.5 0.1 0.014 14.8 0.0 2.5 2 0 0 2 2 2 2 SHNi-TPR TPR_2 PF07719.17 KFM66614.1 - 3.9e-05 23.4 2.0 0.001 19.0 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM66614.1 - 0.00022 21.0 0.3 0.067 13.1 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SPO22 PF08631.10 KFM66614.1 - 0.00063 19.3 4.4 0.0016 18.0 1.6 2.1 1 1 1 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_8 PF13181.6 KFM66614.1 - 0.0007 19.6 1.6 0.018 15.2 0.4 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat MscS_porin PF12795.7 KFM66614.1 - 0.019 14.5 5.1 0.027 14.0 5.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TPR_17 PF13431.6 KFM66614.1 - 0.032 14.6 0.1 0.072 13.5 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TfuA PF07812.12 KFM66614.1 - 0.13 12.0 0.5 0.26 11.0 0.4 1.6 1 1 0 1 1 1 0 TfuA-like protein CODH_A_N PF18537.1 KFM66614.1 - 0.14 12.2 1.1 12 6.0 0.0 2.6 2 1 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Spore_III_AB PF09548.10 KFM66614.1 - 0.15 12.2 2.3 0.24 11.5 1.9 1.6 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TPR_11 PF13414.6 KFM66614.1 - 0.27 10.9 3.5 11 5.8 0.0 3.3 3 1 1 4 4 4 0 TPR repeat PP2C_C PF07830.13 KFM66614.1 - 0.28 11.7 5.0 0.15 12.5 2.0 2.0 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain FAM76 PF16046.5 KFM66614.1 - 2.4 7.4 6.6 1.6 8.0 0.2 2.1 2 0 0 2 2 2 0 FAM76 protein zf-C2H2_4 PF13894.6 KFM66615.1 - 3.3e-09 36.8 109.9 0.071 14.0 2.9 15.7 15 0 0 15 15 15 12 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM66615.1 - 0.0013 19.1 10.7 0.0048 17.3 0.9 15.0 15 0 0 15 15 15 6 Zinc finger, C2H2 type UBA_6 PF18039.1 KFM66615.1 - 0.095 12.6 0.2 2 8.4 0.1 3.0 2 0 0 2 2 2 0 UBA-like domain THAP PF05485.12 KFM66616.1 - 0.00013 22.8 0.0 0.00013 22.8 0.0 2.2 2 1 0 2 2 2 1 THAP domain DDE_3 PF13358.6 KFM66617.1 - 0.0027 17.5 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TF_AP-2 PF03299.14 KFM66618.1 - 0.031 14.2 0.0 0.032 14.2 0.0 1.0 1 0 0 1 1 1 0 Transcription factor AP-2 LRR_8 PF13855.6 KFM66619.1 - 1.1e-39 134.0 49.8 2.1e-10 40.2 2.2 6.7 3 2 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFM66619.1 - 2.1e-32 110.6 57.3 1.6e-05 25.1 2.7 9.2 5 3 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM66619.1 - 6.9e-07 28.9 25.4 0.0041 16.6 2.3 5.2 1 1 5 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 KFM66619.1 - 3e-06 27.0 52.5 4.9 8.1 0.8 13.6 11 3 1 12 12 12 4 Leucine Rich Repeat LRR_5 PF13306.6 KFM66619.1 - 0.014 15.3 0.1 13 5.7 0.0 3.4 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 KFM66619.1 - 0.096 12.7 0.7 21 5.3 0.0 4.4 4 1 0 5 5 5 0 RsmF rRNA methyltransferase first C-terminal domain CSTF_C PF14304.6 KFM66619.1 - 0.22 11.1 5.1 29 4.4 0.2 5.1 5 0 0 5 5 5 0 Transcription termination and cleavage factor C-terminal LRR_6 PF13516.6 KFM66619.1 - 0.57 10.4 43.1 21 5.5 0.1 11.1 11 0 0 11 11 11 0 Leucine Rich repeat HTH_Tnp_Tc3_2 PF01498.18 KFM66620.1 - 2.1e-16 59.9 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66620.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KFM66621.1 - 3.7e-28 98.3 1.0 6.4e-28 97.6 0.4 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM66621.1 - 1.5e-16 60.1 0.2 1.2e-15 57.3 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain BrkDBD PF09607.10 KFM66621.1 - 0.00027 20.7 0.1 0.00097 18.9 0.1 2.0 2 0 0 2 2 2 1 Brinker DNA-binding domain PSRP-3_Ycf65 PF04839.13 KFM66621.1 - 0.36 11.1 2.2 10 6.4 0.2 2.7 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Ribosomal_S13_N PF08069.12 KFM66621.1 - 0.9 9.6 3.2 15 5.7 0.4 3.5 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain RVT_1 PF00078.27 KFM66622.1 - 1.1e-44 152.7 0.0 1.7e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RB_A PF01858.17 KFM66623.1 - 5.8e-79 264.5 0.3 4.7e-76 255.0 0.0 2.6 2 0 0 2 2 2 2 Retinoblastoma-associated protein A domain RB_B PF01857.20 KFM66623.1 - 1.5e-56 190.1 0.0 1.2e-52 177.4 0.0 2.7 2 0 0 2 2 2 2 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KFM66623.1 - 6.1e-50 168.4 0.5 1e-48 164.4 0.3 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) TFIIB PF00382.19 KFM66623.1 - 0.00025 21.1 0.1 0.18 11.8 0.0 2.9 2 0 0 2 2 2 2 Transcription factor TFIIB repeat CAS_C PF12026.8 KFM66624.1 - 5.5e-64 216.1 1.6 5.5e-64 216.1 1.6 1.8 2 0 0 2 2 2 1 Crk-Associated Substrate C-terminal domain Serine_rich PF08824.10 KFM66624.1 - 7.3e-36 123.5 2.7 1.9e-35 122.2 1.0 2.2 2 0 0 2 2 2 1 Serine rich protein interaction domain TMEM213 PF15192.6 KFM66624.1 - 0.046 13.7 0.1 0.096 12.7 0.1 1.5 1 0 0 1 1 1 0 TMEM213 family Syntaxin_2 PF14523.6 KFM66624.1 - 0.24 11.8 1.4 29 5.1 0.2 2.9 2 0 0 2 2 2 0 Syntaxin-like protein HA2 PF04408.23 KFM66626.1 - 5.7e-22 78.0 0.0 1.2e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFM66626.1 - 1.7e-15 57.1 0.1 5e-15 55.6 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFM66626.1 - 1.4e-13 51.2 0.0 3.5e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM66626.1 - 7.2e-07 29.1 0.0 2.1e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFM66626.1 - 0.00018 21.8 0.0 0.0004 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFM66626.1 - 0.039 13.0 0.0 0.087 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KFM66626.1 - 0.043 13.3 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_L27_C PF18471.1 KFM66626.1 - 0.076 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain AAA_30 PF13604.6 KFM66626.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM66626.1 - 0.17 11.6 0.0 0.48 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFM66626.1 - 0.17 12.4 0.0 0.52 10.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter zf-CCCH PF00642.24 KFM66627.1 - 4.5e-11 42.4 23.8 0.00096 19.0 3.4 5.6 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM66627.1 - 3.6e-08 33.2 43.4 0.00082 19.3 0.1 7.8 7 1 0 7 7 7 4 Zinc finger domain zf-CCCH_3 PF15663.5 KFM66627.1 - 4.8e-05 23.5 27.9 0.0042 17.3 3.9 5.0 3 1 2 5 5 5 3 Zinc-finger containing family Torus PF16131.5 KFM66627.1 - 0.0044 17.7 36.2 0.089 13.5 0.7 6.3 3 1 4 7 7 7 3 Torus domain zf-CCCH_4 PF18044.1 KFM66627.1 - 0.15 11.9 0.1 0.15 11.9 0.1 5.9 6 1 0 6 6 6 0 CCCH-type zinc finger Med9 PF07544.13 KFM66627.1 - 1.4 9.0 8.8 0.16 12.1 0.6 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 adh_short PF00106.25 KFM66628.1 - 3.5e-28 98.4 0.0 1.1e-24 87.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase WW PF00397.26 KFM66628.1 - 2.9e-19 68.8 3.7 7e-11 42.0 0.8 3.1 3 0 0 3 3 3 2 WW domain adh_short_C2 PF13561.6 KFM66628.1 - 5.6e-16 58.8 0.0 3.1e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM66628.1 - 1.9e-07 31.2 0.0 3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM66628.1 - 0.013 15.0 0.0 0.044 13.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM66628.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ABC_membrane_2 PF06472.15 KFM66629.1 - 4.8e-07 29.5 0.8 6.4e-07 29.0 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Methyltransf_28 PF02636.17 KFM66630.1 - 3.1e-32 112.2 0.0 3.8e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Piwi PF02171.17 KFM66632.1 - 3.8e-85 285.8 0.0 6e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KFM66632.1 - 7.3e-16 59.0 0.2 3.2e-15 57.0 0.2 2.2 1 1 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KFM66632.1 - 2e-14 53.6 1.0 2e-14 53.6 1.0 2.0 2 0 0 2 2 2 1 PAZ domain ArgoL1 PF08699.10 KFM66632.1 - 3.9e-10 39.2 0.0 7.6e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KFM66632.1 - 1.1e-07 32.1 0.4 1.6e-06 28.3 0.0 3.1 3 0 0 3 3 3 1 Mid domain of argonaute ArgoL2 PF16488.5 KFM66632.1 - 0.0046 17.3 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain MNNL PF07657.13 KFM66633.1 - 1.5e-27 95.4 3.9 1.9e-27 95.1 3.9 1.1 1 0 0 1 1 1 1 N terminus of Notch ligand RabGAP-TBC PF00566.18 KFM66635.1 - 1.7e-49 168.4 0.2 2.8e-49 167.7 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 KFM66635.1 - 3.3e-22 79.8 0.0 1.3e-21 77.8 0.0 2.1 1 1 0 1 1 1 1 Kinesin protein PID PF00640.23 KFM66635.1 - 2.7e-06 27.5 0.2 6e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFM66635.1 - 0.0031 17.7 0.0 0.0072 16.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain A_deaminase_N PF08451.11 KFM66635.1 - 0.058 13.7 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal DUF4863 PF16155.5 KFM66636.1 - 0.051 13.4 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4863) APG6_N PF17675.1 KFM66636.1 - 0.17 12.4 38.0 2.9 8.4 5.1 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KFM66636.1 - 0.42 10.8 34.2 0.4 10.9 5.9 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 KFM66636.1 - 0.42 10.9 4.6 13 6.1 1.0 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2852 PF11014.8 KFM66636.1 - 0.43 10.8 4.8 0.17 12.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) UPF0242 PF06785.11 KFM66636.1 - 0.6 10.2 40.1 2.5 8.2 3.4 3.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 KFM66636.1 - 0.71 9.4 32.2 1.5 8.3 9.8 2.6 1 1 1 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.12 KFM66636.1 - 0.79 9.8 16.3 0.048 13.7 3.5 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 KFM66636.1 - 0.84 8.9 39.8 1.4 8.2 27.8 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 KFM66636.1 - 1.5 9.1 22.4 0.79 10.0 1.9 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) PIN_6 PF17146.4 KFM66636.1 - 2.3 8.8 6.0 0.45 11.1 0.7 2.6 3 0 0 3 3 3 0 PIN domain of ribonuclease ADIP PF11559.8 KFM66636.1 - 2.4 8.2 32.7 0.046 13.8 16.8 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 KFM66636.1 - 3.5 6.7 39.9 0.14 11.3 25.1 2.5 1 1 2 3 3 3 0 Myosin-like coiled-coil protein Golgin_A5 PF09787.9 KFM66636.1 - 5.6 6.3 32.1 1.6 8.2 22.1 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF883 PF05957.13 KFM66636.1 - 7.1 7.3 9.6 3.4 8.4 3.6 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 KFM66636.1 - 9.3 6.3 16.1 0.39 10.7 4.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HTH_Tnp_Tc3_2 PF01498.18 KFM66637.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66637.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66637.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66637.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66637.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain 2-oxoacid_dh PF00198.23 KFM66638.1 - 3.6e-50 170.6 0.7 4.8e-50 170.2 0.7 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFM66638.1 - 4.2e-20 71.3 3.2 9.7e-20 70.2 3.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFM66638.1 - 7.5e-10 39.0 0.0 2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFM66638.1 - 9.9e-05 22.1 0.8 0.0012 18.7 0.0 2.7 3 0 0 3 3 3 1 Biotin-lipoyl like QRPTase_N PF02749.16 KFM66638.1 - 0.032 14.3 0.0 0.12 12.5 0.0 1.9 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain DM13 PF10517.9 KFM66639.1 - 1.2e-39 135.0 1.1 5.7e-25 87.9 0.0 4.0 5 0 0 5 5 5 2 Electron transfer DM13 DOMON PF03351.17 KFM66639.1 - 8.9e-15 55.0 0.0 2.6e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 DOMON domain TPR_19 PF14559.6 KFM66640.1 - 0.00042 20.8 0.4 0.036 14.6 0.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM66640.1 - 0.0019 18.9 0.1 0.18 12.7 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM66640.1 - 0.0028 17.6 2.8 0.43 10.8 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM66640.1 - 0.022 15.0 0.5 0.21 11.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM66640.1 - 0.046 14.4 0.6 0.41 11.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat YfdX PF10938.8 KFM66640.1 - 0.088 12.7 0.4 3.1 7.7 0.0 2.7 3 0 0 3 3 3 0 YfdX protein ANAPC3 PF12895.7 KFM66640.1 - 0.25 11.6 3.8 5.5 7.3 0.0 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC5 PF12862.7 KFM66641.1 - 5.7e-27 93.6 2.5 5.7e-27 93.6 2.5 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 KFM66641.1 - 0.022 15.0 0.7 0.063 13.6 0.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFM66641.1 - 0.51 11.1 3.6 0.18 12.5 0.6 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT_LIKE_ACTX PF17556.2 KFM66642.1 - 0.072 13.7 1.8 0.11 13.1 1.8 1.3 1 0 0 1 1 1 0 MIT-like atracotoxin family Fungus-induced PF10917.8 KFM66643.1 - 0.053 13.8 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Fungus-induced protein MIT_LIKE_ACTX PF17556.2 KFM66644.1 - 7.6e-05 23.2 13.8 0.0043 17.6 13.8 2.1 1 1 0 1 1 1 1 MIT-like atracotoxin family Fungus-induced PF10917.8 KFM66644.1 - 0.045 14.1 0.3 0.065 13.6 0.3 1.3 1 0 0 1 1 1 0 Fungus-induced protein TANGO2 PF05742.12 KFM66645.1 - 1.1e-64 219.0 0.0 1.2e-64 218.8 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 GlutR_dimer PF00745.20 KFM66645.1 - 0.053 14.0 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain fn3 PF00041.21 KFM66646.1 - 7.2e-13 48.7 0.0 7.4e-05 23.0 0.1 3.5 3 0 0 3 3 3 2 Fibronectin type III domain TMP-TENI PF02581.17 KFM66646.1 - 0.013 14.8 0.7 1.3 8.3 0.0 3.1 1 1 1 3 3 3 0 Thiamine monophosphate synthase Pur_ac_phosph_N PF16656.5 KFM66646.1 - 0.023 15.3 0.0 0.023 15.3 0.0 3.4 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 KFM66646.1 - 0.072 13.0 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Fibronectin-III type domain MDM1 PF15501.6 KFM66647.1 - 3.7e-18 66.0 20.6 3.7e-18 66.0 20.6 3.3 2 2 2 4 4 4 3 Nuclear protein MDM1 CUB PF00431.20 KFM66648.1 - 1e-46 157.8 1.2 1.1e-21 77.2 0.1 3.2 3 0 0 3 3 3 3 CUB domain CUB PF00431.20 KFM66649.1 - 1.6e-22 79.9 0.0 4.1e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 CUB domain zf-LITAF-like PF10601.9 KFM66651.1 - 2.5e-18 66.1 7.6 3.3e-18 65.7 7.6 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Sgf11 PF08209.11 KFM66651.1 - 0.00098 18.6 0.5 0.25 10.9 0.0 2.5 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-ribbon_3 PF13248.6 KFM66651.1 - 0.0024 17.2 2.7 0.87 9.1 0.7 2.7 2 0 0 2 2 2 2 zinc-ribbon domain zf_Rg PF17915.1 KFM66651.1 - 0.0091 15.4 0.3 0.16 11.4 0.0 2.6 2 0 0 2 2 2 1 Reverse gyrase zinc finger Zn_Tnp_IS91 PF14319.6 KFM66651.1 - 0.013 15.5 3.4 0.32 11.0 0.2 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain zinc_ribbon_2 PF13240.6 KFM66651.1 - 0.025 14.3 4.4 0.71 9.7 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ISL3 PF14690.6 KFM66651.1 - 0.054 14.2 3.8 1.4 9.6 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_15 PF17032.5 KFM66651.1 - 0.06 14.1 5.3 3.4 8.5 5.3 2.3 1 1 0 1 1 1 0 zinc-ribbon family DUF2318 PF10080.9 KFM66651.1 - 0.061 13.4 0.3 0.061 13.4 0.3 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) DUF1610 PF07754.11 KFM66651.1 - 0.076 13.0 5.9 0.076 13.0 5.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) DNA_RNApol_7kD PF03604.13 KFM66651.1 - 0.082 12.6 0.6 0.082 12.6 0.6 2.7 3 0 0 3 3 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_SprT PF17283.2 KFM66651.1 - 0.087 12.7 5.6 0.77 9.7 0.2 2.8 2 1 1 3 3 3 0 SprT-like zinc ribbon domain TF_Zn_Ribbon PF08271.12 KFM66651.1 - 0.12 11.9 8.2 1.2 8.7 0.3 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding Ribosomal_L32p PF01783.23 KFM66651.1 - 0.19 12.0 1.0 3.9 7.8 0.3 2.3 2 0 0 2 2 2 0 Ribosomal L32p protein family Zn-ribbon_8 PF09723.10 KFM66651.1 - 0.22 11.7 7.5 2.6 8.2 0.1 2.4 2 1 0 2 2 2 0 Zinc ribbon domain VHS PF00790.19 KFM66651.1 - 0.24 11.3 0.1 0.4 10.5 0.1 1.3 1 0 0 1 1 1 0 VHS domain HypA PF01155.19 KFM66651.1 - 0.33 11.0 5.0 0.79 9.8 5.0 1.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KFM66651.1 - 0.36 10.9 7.8 2.8 8.1 7.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon GFA PF04828.14 KFM66651.1 - 0.39 11.1 5.4 2.7 8.4 0.9 2.3 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF3268 PF11672.8 KFM66651.1 - 0.75 10.1 3.9 5.2 7.4 0.2 2.1 1 1 1 2 2 2 0 zinc-finger-containing domain Zn_Tnp_IS1595 PF12760.7 KFM66651.1 - 0.89 9.6 7.8 7.2 6.7 0.5 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 KFM66651.1 - 1.3 9.0 10.6 3.6 7.6 0.6 3.2 3 0 0 3 3 3 0 Nudix N-terminal DUF1272 PF06906.11 KFM66651.1 - 1.6 8.9 8.5 39 4.4 8.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-dskA_traR PF01258.17 KFM66651.1 - 1.7 8.6 5.9 8.6 6.4 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger zf_UBZ PF18439.1 KFM66651.1 - 2 8.1 5.2 11 5.7 0.0 2.6 3 0 0 3 3 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_10 PF10058.9 KFM66651.1 - 4.3 7.1 9.4 27 4.6 1.9 2.7 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein OrfB_Zn_ribbon PF07282.11 KFM66651.1 - 9.1 6.3 8.0 35 4.4 2.2 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF3552 PF12072.8 KFM66654.1 - 0.012 15.1 5.3 0.03 13.8 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CemA PF03040.14 KFM66654.1 - 0.35 10.8 5.7 0.055 13.4 1.5 1.7 2 0 0 2 2 2 0 CemA family AT_hook PF02178.19 KFM66655.1 - 0.16 11.9 27.4 0.063 13.2 1.3 3.9 3 0 0 3 3 3 0 AT hook motif WD40 PF00400.32 KFM66656.1 - 0.068 14.1 0.9 0.12 13.3 0.4 1.7 2 0 0 2 2 2 0 WD domain, G-beta repeat KCNQ_channel PF03520.14 KFM66658.1 - 3e-24 85.9 7.2 1.5e-23 83.7 5.8 2.4 1 1 1 2 2 2 1 KCNQ voltage-gated potassium channel PDE8 PF08629.10 KFM66658.1 - 0.034 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 PDE8 phosphodiesterase GCR1_C PF12550.8 KFM66658.1 - 0.059 13.7 1.7 1.7 9.0 0.0 3.0 2 1 1 3 3 3 0 Transcriptional activator of glycolytic enzymes HTH_Tnp_Tc3_2 PF01498.18 KFM66659.1 - 9.5e-16 57.8 6.5 1.8e-15 56.9 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66659.1 - 2.7e-15 56.4 0.1 2.8e-14 53.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM66659.1 - 0.00087 19.9 1.5 0.00087 19.9 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM66659.1 - 0.0038 17.0 0.1 0.14 12.0 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66659.1 - 0.018 15.1 0.1 0.077 13.1 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM66659.1 - 0.042 13.9 0.4 0.042 13.9 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix DUF4477 PF14780.6 KFM66660.1 - 4e-22 78.8 8.6 4e-22 78.8 8.6 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4477) LPD11 PF18824.1 KFM66660.1 - 0.0023 18.0 0.9 2.4 8.3 0.2 3.1 2 0 0 2 2 2 2 Large polyvalent protein-associated domain 11 Enkurin PF13864.6 KFM66660.1 - 0.0042 17.5 6.0 0.0092 16.4 1.9 2.9 3 0 0 3 3 3 1 Calmodulin-binding HTH_Tnp_Tc3_2 PF01498.18 KFM66661.1 - 2.4e-16 59.7 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66661.1 - 8.9e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66662.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66662.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_11 PF13414.6 KFM66663.1 - 4.7e-10 39.0 0.1 3.1e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.28 KFM66663.1 - 2.1e-09 36.8 0.4 0.0023 17.7 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM66663.1 - 3.1e-08 33.1 0.2 0.0023 17.9 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM66663.1 - 3.5e-05 24.3 0.1 0.057 14.3 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM66663.1 - 0.001 19.3 2.6 0.0062 16.8 0.7 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM66663.1 - 0.0026 18.2 1.3 1.7 9.2 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM66663.1 - 0.0034 17.3 0.6 0.38 10.9 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM66663.1 - 0.0057 17.3 0.1 0.016 15.8 0.1 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM66663.1 - 0.0083 16.3 0.5 0.0091 16.1 0.5 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM66663.1 - 0.015 15.6 0.1 0.041 14.3 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 KFM66663.1 - 0.016 14.7 1.2 0.51 9.8 0.3 2.0 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain PPR PF01535.20 KFM66664.1 - 0.0028 17.8 0.1 0.004 17.3 0.1 1.2 1 0 0 1 1 1 1 PPR repeat TPR_10 PF13374.6 KFM66664.1 - 0.0029 17.4 0.1 0.003 17.4 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM66664.1 - 0.004 17.1 0.1 0.0046 17.0 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM66664.1 - 0.02 14.7 0.1 0.027 14.3 0.1 1.3 1 1 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.9 KFM66664.1 - 0.024 14.4 0.0 0.025 14.3 0.0 1.0 1 0 0 1 1 1 0 26S proteasome subunit RPN7 PPR_2 PF13041.6 KFM66664.1 - 0.051 13.8 0.0 0.059 13.6 0.0 1.1 1 0 0 1 1 1 0 PPR repeat family TPR_12 PF13424.6 KFM66664.1 - 0.07 13.4 0.0 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5446 PF17522.2 KFM66667.1 - 1.9 8.7 5.7 0.42 10.8 1.3 2.1 2 1 1 3 3 3 0 Family of unknown function (DUF5446) bZIP_1 PF00170.21 KFM66668.1 - 0.011 15.8 0.9 0.011 15.8 0.9 2.3 1 1 1 2 2 2 0 bZIP transcription factor TMF_TATA_bd PF12325.8 KFM66668.1 - 0.014 15.6 7.1 0.032 14.5 4.3 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding YscO-like PF16789.5 KFM66668.1 - 0.02 14.9 6.6 0.027 14.5 6.6 1.2 1 0 0 1 1 1 0 YscO-like protein Vip3A_N PF12495.8 KFM66668.1 - 0.035 14.0 0.6 0.036 14.0 0.6 1.1 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Phage_GP20 PF06810.11 KFM66668.1 - 0.077 12.8 9.2 0.26 11.1 9.1 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 TMPIT PF07851.13 KFM66668.1 - 0.19 10.9 7.5 0.2 10.9 7.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 KFM66668.1 - 0.25 10.7 4.6 0.3 10.4 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3498 PF12004.8 KFM66668.1 - 0.3 10.2 6.2 0.34 10.1 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) 5_nucleotid PF05761.14 KFM66668.1 - 0.34 9.8 5.4 0.39 9.6 5.4 1.0 1 0 0 1 1 1 0 5' nucleotidase family DUF4404 PF14357.6 KFM66668.1 - 0.61 10.8 7.7 1.7 9.4 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Vir_act_alpha_C PF10400.9 KFM66668.1 - 0.67 10.7 5.8 3.1 8.5 1.4 2.7 1 1 2 3 3 3 0 Virulence activator alpha C-term Fib_alpha PF08702.10 KFM66668.1 - 1.1 9.5 7.5 1.8 8.8 7.5 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Med21 PF11221.8 KFM66668.1 - 1.1 9.5 9.0 2.1 8.6 9.0 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex FlxA PF14282.6 KFM66668.1 - 1.3 9.0 12.1 1.6 8.8 12.1 1.1 1 0 0 1 1 1 0 FlxA-like protein SlyX PF04102.12 KFM66668.1 - 1.7 9.3 6.3 1.9 9.2 3.3 2.3 1 1 1 2 2 2 0 SlyX RB_B PF01857.20 KFM66669.1 - 2.1e-24 86.0 6.4 6e-24 84.6 6.4 1.7 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Neur_chan_LBD PF02931.23 KFM66670.1 - 7.3e-42 143.2 0.3 1e-41 142.7 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM66670.1 - 2.2e-26 93.4 3.3 2.4e-25 90.0 1.2 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DDE_1 PF03184.19 KFM66671.1 - 3.6e-50 170.0 0.1 6.4e-50 169.2 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM66671.1 - 1.7e-12 47.1 0.0 1.4e-11 44.2 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM66672.1 - 4.9e-16 58.7 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66672.1 - 6.5e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66672.1 - 2.2e-07 30.5 1.2 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66672.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66672.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM66673.1 - 3.6e-16 59.3 0.1 3.1e-15 56.2 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66673.1 - 1.4e-10 41.2 1.0 2.8e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DUF4885 PF16226.5 KFM66674.1 - 0.00027 20.1 1.0 0.00031 19.9 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4885) XLF PF09302.11 KFM66674.1 - 0.016 15.4 1.7 0.019 15.1 1.7 1.1 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component CytochromB561_N PF09786.9 KFM66674.1 - 0.022 13.8 0.1 0.024 13.7 0.1 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal MHC_II_beta PF00969.19 KFM66674.1 - 0.059 13.5 0.1 0.076 13.1 0.1 1.2 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain YebO PF13974.6 KFM66674.1 - 0.58 10.3 6.4 0.77 9.9 6.4 1.3 1 0 0 1 1 1 0 YebO-like protein zf-met PF12874.7 KFM66676.1 - 6.9e-05 23.1 15.0 0.16 12.4 1.0 5.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM66676.1 - 0.00041 21.0 33.9 0.18 12.7 2.4 6.9 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM66676.1 - 0.017 15.5 34.6 0.22 12.1 1.8 6.8 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KFM66676.1 - 0.025 15.3 6.3 6.9 7.4 0.8 3.8 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 KFM66676.1 - 3.1 8.4 16.3 1.4 9.5 0.3 5.4 5 0 0 5 5 5 0 Zinc-finger double domain Neur_chan_LBD PF02931.23 KFM66677.1 - 5.7e-05 22.7 0.0 6.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DDE_1 PF03184.19 KFM66678.1 - 3.5e-50 170.1 0.1 6.8e-50 169.1 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM66678.1 - 1.8e-12 47.1 0.0 1.5e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain GSK-3_bind PF05350.12 KFM66679.1 - 2.7e-06 26.9 0.1 0.00012 21.5 0.0 2.1 1 1 1 2 2 2 2 Glycogen synthase kinase-3 binding HPIP PF15226.6 KFM66679.1 - 0.051 14.0 0.3 9.4 6.7 0.2 2.1 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family His_Phos_2 PF00328.22 KFM66680.1 - 3e-10 40.0 0.3 2e-06 27.4 0.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KFM66681.1 - 5.2e-18 65.6 0.0 3.9e-17 62.7 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KFM66682.1 - 7e-19 68.4 2.0 4.7e-16 59.1 2.0 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KFM66683.1 - 2.9e-18 66.4 1.7 1.4e-15 57.6 0.1 3.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF2270 PF10028.9 KFM66683.1 - 0.044 13.3 0.2 0.079 12.5 0.2 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) RdRP PF05183.12 KFM66684.1 - 2.1e-152 508.8 0.3 3.5e-152 508.1 0.3 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase Anemone_cytotox PF06369.12 KFM66684.1 - 0.026 14.1 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Sea anemone cytotoxic protein GDI PF00996.18 KFM66685.1 - 6.2e-53 179.9 0.0 1.8e-37 128.9 0.0 2.0 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KFM66685.1 - 0.0037 17.5 0.0 0.008 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFM66685.1 - 0.034 13.5 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DDE_3 PF13358.6 KFM66686.1 - 0.092 12.5 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Myotub-related PF06602.14 KFM66688.1 - 0.00015 20.8 0.1 0.00018 20.6 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFM66688.1 - 0.018 14.6 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM66688.1 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFM66688.1 - 0.066 12.8 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3876 PF12992.7 KFM66689.1 - 0.033 14.3 0.1 0.046 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) DUF4347 PF14252.6 KFM66690.1 - 0.0054 16.6 0.0 0.014 15.2 0.0 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4347) Pkinase PF00069.25 KFM66690.1 - 0.068 12.5 0.7 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Ssu72 PF04722.13 KFM66693.1 - 8.2e-41 139.7 0.6 9.1e-41 139.5 0.6 1.0 1 0 0 1 1 1 1 Ssu72-like protein NYN_YacP PF05991.11 KFM66693.1 - 0.0034 17.3 0.1 0.0041 17.1 0.1 1.1 1 0 0 1 1 1 1 YacP-like NYN domain OSK PF17182.4 KFM66693.1 - 0.06 12.6 0.1 0.076 12.2 0.1 1.2 1 0 0 1 1 1 0 OSK domain Pro_isomerase PF00160.21 KFM66695.1 - 1.4e-48 165.2 0.0 1.5e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD dsrm PF00035.26 KFM66696.1 - 3.5e-25 88.5 0.3 1.4e-11 44.9 0.1 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 KFM66696.1 - 1.6e-14 54.0 0.0 3.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFM66696.1 - 2.1e-14 53.8 0.0 4.9e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KFM66696.1 - 2.5e-12 47.0 0.0 6.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 KFM66696.1 - 3.3e-07 30.2 0.0 1e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 KFM66696.1 - 2.6e-05 24.3 0.0 0.1 12.7 0.0 3.0 2 0 0 2 2 2 2 Dicer dimerisation domain DND1_DSRM PF14709.7 KFM66696.1 - 0.0047 17.2 0.1 0.55 10.5 0.0 2.8 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 ATPase PF06745.13 KFM66696.1 - 0.01 15.2 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.6 KFM66696.1 - 0.071 13.2 0.0 0.24 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM66696.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 KFM66696.1 - 0.16 12.0 0.0 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DDE_1 PF03184.19 KFM66697.1 - 2.7e-05 23.9 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Cluap1 PF10234.9 KFM66698.1 - 1.1e-12 47.9 6.7 1.8e-12 47.3 6.7 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 FtsX_ECD PF18075.1 KFM66698.1 - 0.049 14.3 0.6 0.086 13.5 0.6 1.5 1 0 0 1 1 1 0 FtsX extracellular domain USP7_C2 PF14533.6 KFM66698.1 - 0.085 12.6 3.1 0.13 12.0 3.1 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal zf-H2C2_2 PF13465.6 KFM66699.1 - 1.5e-110 357.1 105.6 3.2e-09 36.8 1.0 16.1 16 0 0 16 16 16 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66699.1 - 5e-66 215.6 122.9 8e-06 26.0 0.8 15.1 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66699.1 - 1.3e-51 168.8 119.2 0.00041 21.0 1.1 15.2 15 0 0 15 15 15 15 C2H2-type zinc finger zf-met PF12874.7 KFM66699.1 - 1.3e-34 117.5 108.0 0.00016 21.9 0.6 15.4 15 0 0 15 15 15 14 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM66699.1 - 5.2e-25 86.9 100.8 0.0014 18.5 0.7 15.9 15 1 0 15 15 15 13 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM66699.1 - 8.2e-16 57.8 50.2 0.062 13.4 0.1 14.6 5 3 10 15 15 15 6 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KFM66699.1 - 1.3e-14 54.0 83.0 0.025 14.9 0.0 15.1 14 1 1 15 15 14 8 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM66699.1 - 5.1e-05 23.5 28.1 2.2 8.6 2.9 8.4 1 1 7 8 8 8 3 BolA-like protein DUF3338 PF11819.8 KFM66699.1 - 0.0019 18.2 0.1 25 4.9 0.0 5.3 3 1 4 7 7 7 0 Domain of unknown function (DUF3338) zf-C2H2_11 PF16622.5 KFM66699.1 - 0.0064 16.2 87.9 0.42 10.4 1.9 14.3 15 0 0 15 15 15 6 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFM66699.1 - 0.012 15.5 61.9 4.7 7.1 0.6 13.9 1 1 14 15 15 15 0 C2H2 type zinc-finger (1 copy) Alk_phosphatase PF00245.20 KFM66699.1 - 0.014 14.4 1.8 0.098 11.6 0.1 2.0 2 0 0 2 2 2 0 Alkaline phosphatase zf-C2H2_2 PF12756.7 KFM66699.1 - 0.022 15.1 104.7 1.3 9.4 1.0 14.6 1 1 13 14 14 14 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM66699.1 - 0.029 15.1 57.2 1.5 9.6 3.9 7.9 2 2 5 8 8 8 0 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM66699.1 - 0.067 13.3 52.3 7.7 6.7 2.8 6.6 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type Yop-YscD_ppl PF16693.5 KFM66699.1 - 0.1 12.0 0.0 11 5.4 0.0 3.1 3 0 0 3 3 3 0 Inner membrane component of T3SS, periplasmic domain C1_1 PF00130.22 KFM66699.1 - 0.17 11.8 81.3 2.4 8.1 3.6 12.3 2 2 11 13 13 13 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KFM66699.1 - 0.29 11.1 53.5 0.57 10.2 0.5 9.5 4 1 5 9 9 9 0 Adenylate kinase, active site lid FYVE PF01363.21 KFM66699.1 - 9.2 6.5 80.9 0.86 9.8 1.7 8.4 3 1 5 8 8 8 0 FYVE zinc finger zf-H2C2_2 PF13465.6 KFM66700.1 - 3.6e-33 112.5 23.5 4.4e-10 39.5 0.5 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66700.1 - 6.4e-26 89.3 29.3 5.5e-07 29.7 1.7 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66700.1 - 1.2e-17 63.1 27.8 0.00017 22.2 1.7 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFM66700.1 - 3.1e-15 56.0 29.0 0.00025 21.3 1.8 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM66700.1 - 1.3e-09 37.7 21.3 1.6e-05 24.6 0.0 4.5 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM66700.1 - 4.2e-08 33.3 19.9 0.032 14.5 1.3 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM66700.1 - 4.6e-05 23.3 8.8 0.055 13.5 3.1 2.4 2 1 0 2 2 2 2 Adenylate kinase, active site lid GAGA PF09237.11 KFM66700.1 - 0.00011 22.0 3.8 0.52 10.2 0.2 3.4 1 1 3 4 4 4 2 GAGA factor zf-DBF PF07535.12 KFM66700.1 - 0.0002 21.4 14.9 2.7 8.2 0.2 4.3 4 0 0 4 4 4 3 DBF zinc finger zf-C2H2_6 PF13912.6 KFM66700.1 - 0.00022 21.1 30.0 0.047 13.7 1.5 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger TRAF6_Z2 PF18048.1 KFM66700.1 - 0.0005 20.1 15.6 0.16 12.1 0.3 4.2 4 0 0 4 4 4 2 TNF receptor-associated factor 6 zinc finger 2 BolA PF01722.18 KFM66700.1 - 0.0015 18.8 2.5 0.93 9.8 0.7 2.6 1 1 2 3 3 3 2 BolA-like protein zf-C2H2_9 PF16293.5 KFM66700.1 - 0.0017 18.1 13.2 2.5 8.0 0.3 4.0 1 1 3 4 4 4 3 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM66700.1 - 0.0022 17.9 13.9 1.3 9.0 0.1 4.3 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFM66700.1 - 0.0024 18.2 23.3 0.22 11.8 1.5 4.0 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM66700.1 - 0.007 16.0 14.3 2.2 8.0 0.2 4.0 1 1 3 4 4 4 1 MYST family zinc finger domain C1_1 PF00130.22 KFM66700.1 - 0.0095 15.8 15.9 0.91 9.5 4.9 3.7 1 1 3 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HNH_5 PF14279.6 KFM66700.1 - 0.015 15.2 15.4 1.5 8.7 0.1 3.9 2 1 0 3 3 3 0 HNH endonuclease zf-Sec23_Sec24 PF04810.15 KFM66700.1 - 0.017 15.1 14.2 0.94 9.6 1.0 4.1 2 1 2 4 4 4 0 Sec23/Sec24 zinc finger Endonuclease_7 PF02945.15 KFM66700.1 - 0.029 14.3 16.0 0.036 14.0 5.3 2.8 1 1 2 3 3 3 0 Recombination endonuclease VII zf-C2H2_3rep PF18868.1 KFM66700.1 - 0.029 15.1 11.1 2 9.1 11.1 3.1 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 KFM66700.1 - 0.032 14.3 24.6 0.32 11.1 1.2 4.1 1 1 3 4 4 4 0 BED zinc finger zf_UBZ PF18439.1 KFM66700.1 - 0.051 13.2 13.3 4.1 7.1 0.3 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Tox-HNH-HHH PF15637.6 KFM66700.1 - 0.051 13.7 0.2 0.37 11.0 0.1 1.9 1 1 1 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-CHCC PF10276.9 KFM66700.1 - 0.092 12.8 3.3 31 4.8 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger domain zf-RRPl_C4 PF17026.5 KFM66700.1 - 0.11 12.6 12.0 0.095 12.8 7.0 2.2 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type PqqA PF08042.11 KFM66700.1 - 0.21 11.7 0.2 1.6e+02 2.5 0.0 3.7 4 0 0 4 4 4 0 PqqA family zf-HIT PF04438.16 KFM66700.1 - 0.3 11.0 15.7 8.2 6.4 0.3 4.1 4 0 0 4 4 4 0 HIT zinc finger zf-C2H2_11 PF16622.5 KFM66700.1 - 0.35 10.7 0.1 0.35 10.7 0.1 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFM66700.1 - 0.37 11.6 13.2 1.7 9.5 2.0 2.2 1 1 1 2 2 2 0 zinc-ribbon family zf-Paramyx-P PF13008.7 KFM66700.1 - 0.62 9.6 7.8 25 4.4 0.0 3.9 4 0 0 4 4 4 0 Zinc-binding domain of Paramyxoviridae V protein XPA_N PF01286.18 KFM66700.1 - 0.63 10.1 11.1 19 5.4 0.1 4.0 4 0 0 4 4 4 0 XPA protein N-terminal FYVE PF01363.21 KFM66700.1 - 0.89 9.7 16.9 38 4.5 0.2 2.6 1 1 1 2 2 2 0 FYVE zinc finger zf-trcl PF13451.6 KFM66700.1 - 0.97 9.4 10.1 13 5.8 0.1 4.0 4 0 0 4 4 4 0 Probable zinc-ribbon domain DUF5330 PF17264.2 KFM66700.1 - 2.9 7.9 7.2 65 3.6 0.1 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5330) zf-H2C2_2 PF13465.6 KFM66701.1 - 0.00038 20.7 0.7 0.00045 20.5 0.1 1.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66701.1 - 0.0043 17.4 0.3 0.0043 17.4 0.3 1.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM66701.1 - 0.091 12.8 0.4 0.091 12.8 0.4 1.5 2 0 0 2 2 2 0 C2H2-type zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM66703.1 - 6.3e-16 58.4 2.2 6.3e-16 58.4 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM66703.1 - 1.4e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66703.1 - 3.2e-07 30.0 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66703.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain MLVIN_C PF18697.1 KFM66704.1 - 0.055 13.6 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain SH3_11 PF18103.1 KFM66704.1 - 0.091 12.9 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain DDE_3 PF13358.6 KFM66705.1 - 7.3e-08 32.3 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4786 PF16027.5 KFM66706.1 - 0.0013 19.3 0.0 0.73 10.4 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4786) DUF4332 PF14229.6 KFM66708.1 - 0.039 14.2 0.5 0.063 13.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) SWIRM PF04433.17 KFM66708.1 - 0.41 11.0 3.7 0.36 11.2 1.4 2.0 1 1 1 2 2 2 0 SWIRM domain Kinesin PF00225.23 KFM66709.1 - 1.8e-112 375.6 0.6 2e-112 375.4 0.6 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM66709.1 - 3e-26 92.2 0.0 4.9e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding ResIII PF04851.15 KFM66709.1 - 0.044 13.8 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM66710.1 - 2.8e-48 164.0 0.0 5.3e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM66710.1 - 8.1e-28 97.0 0.0 1.6e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM66710.1 - 0.00019 21.5 0.0 0.00044 20.3 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFM66710.1 - 0.033 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 KFM66710.1 - 0.18 12.1 0.0 29 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Reeler PF02014.16 KFM66711.1 - 1.9e-25 90.1 0.1 4.3e-25 88.9 0.1 1.6 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.17 KFM66711.1 - 1.5e-09 38.1 0.0 4e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KFM66711.1 - 2.5e-06 27.7 7.0 2.5e-06 27.7 7.0 1.7 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 ODV-E18 PF10717.9 KFM66711.1 - 0.034 14.0 1.8 0.76 9.7 0.0 3.0 2 1 1 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 TrbC PF04956.13 KFM66711.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.6 2 1 0 2 2 2 0 TrbC/VIRB2 family Claudin_3 PF06653.11 KFM66711.1 - 4.8 7.1 15.7 0.11 12.5 7.0 2.3 1 1 1 2 2 2 0 Tight junction protein, Claudin-like DUF3810 PF12725.7 KFM66711.1 - 7.4 5.8 9.7 1.4 8.1 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) RIC3 PF15361.6 KFM66712.1 - 2.7e-07 31.1 0.0 3.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 DUF2852 PF11014.8 KFM66712.1 - 0.051 13.7 0.0 0.061 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) RIC3 PF15361.6 KFM66713.1 - 1.3e-12 48.3 0.2 1.5e-12 48.1 0.2 1.2 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 DUF3377 PF11857.8 KFM66713.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) SLC35F PF06027.12 KFM66713.1 - 0.055 13.0 0.1 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 Solute carrier family 35 EMP24_GP25L PF01105.24 KFM66714.1 - 6.4e-24 84.9 0.8 6.4e-24 84.9 0.8 1.3 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD HAUS-augmin3 PF14932.6 KFM66715.1 - 0.28 10.7 6.7 0.67 9.5 3.2 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 BLOC1S3 PF15753.5 KFM66716.1 - 1e-22 81.1 7.1 3.2e-22 79.5 7.1 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Atg14 PF10186.9 KFM66716.1 - 0.002 17.2 2.6 0.003 16.7 2.6 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 KFM66716.1 - 0.32 11.6 2.5 0.63 10.7 2.5 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 XkdW PF09636.10 KFM66716.1 - 0.76 9.9 3.2 4.6 7.4 0.4 2.5 2 1 1 3 3 3 0 XkdW protein DDE_Tnp_1_7 PF13843.6 KFM66717.1 - 3.3e-20 72.7 0.1 3.6e-20 72.6 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 UQ_con PF00179.26 KFM66719.1 - 2.2e-32 111.6 0.0 2.8e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RdRP_2 PF00978.21 KFM66719.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase DHDPS PF00701.22 KFM66720.1 - 2e-47 161.3 0.0 2.6e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DDE_Tnp_4 PF13359.6 KFM66722.1 - 9e-12 44.9 0.3 1.1e-11 44.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM66722.1 - 2.7e-05 23.9 0.0 3.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Antirestrict PF03230.13 KFM66722.1 - 0.045 13.8 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 Antirestriction protein HTH_Tnp_Tc3_2 PF01498.18 KFM66724.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66724.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM66725.1 - 8.8e-11 41.7 0.0 9.5e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66727.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66727.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66727.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66727.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66727.1 - 2 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain WD40 PF00400.32 KFM66729.1 - 3e-25 88.0 5.2 2.2e-10 40.9 0.2 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM66729.1 - 5.2e-09 36.3 0.5 0.0054 17.0 0.0 2.9 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM66729.1 - 0.0013 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A BING4CT PF08149.11 KFM66729.1 - 0.0034 17.2 0.0 3.2 7.6 0.0 2.3 2 0 0 2 2 2 2 BING4CT (NUC141) domain Katanin_con80 PF13925.6 KFM66730.1 - 0.0035 17.4 0.1 0.0057 16.7 0.1 1.4 1 0 0 1 1 1 1 con80 domain of Katanin RhoGEF PF00621.20 KFM66733.1 - 0.00014 22.2 4.0 0.00031 21.0 4.0 1.6 1 1 0 1 1 1 1 RhoGEF domain DIT1_PvcA PF05141.12 KFM66733.1 - 0.042 13.3 0.1 0.063 12.7 0.1 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF2153 PF09921.9 KFM66733.1 - 0.087 12.6 0.3 0.28 11.0 0.2 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) DUF5344 PF17279.2 KFM66733.1 - 0.34 11.5 2.2 9.1 6.9 0.0 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5344) AbiH PF14253.6 KFM66733.1 - 0.76 9.6 7.2 0.3 10.9 2.8 2.1 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH A_deamin PF02137.18 KFM66734.1 - 3.4e-101 339.0 0.0 7e-101 338.0 0.0 1.5 2 0 0 2 2 2 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 KFM66734.1 - 5.7e-24 84.6 1.3 1.3e-12 48.3 0.3 3.1 3 0 0 3 3 3 2 Double-stranded RNA binding motif LRR_9 PF14580.6 KFM66734.1 - 9.7e-16 57.8 2.3 2.1e-15 56.7 2.3 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFM66734.1 - 7.7e-13 48.4 19.1 3.8e-06 27.1 9.4 3.1 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM66734.1 - 2.3e-07 30.4 18.0 0.0009 19.0 1.7 2.8 2 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 KFM66734.1 - 1.7e-05 24.5 18.3 0.01 15.8 1.4 4.1 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 KFM66734.1 - 0.0084 16.5 14.7 5.9 7.8 0.4 4.7 3 1 0 3 3 3 3 Leucine Rich Repeat LRR_5 PF13306.6 KFM66734.1 - 0.044 13.7 0.9 0.099 12.6 0.9 1.6 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Alpha_Helical PF18489.1 KFM66734.1 - 0.055 13.7 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Alpha helical domain LPP20 PF02169.16 KFM66734.1 - 0.083 13.2 1.5 3 8.2 0.1 2.8 2 0 0 2 2 2 0 LPP20 lipoprotein WD40 PF00400.32 KFM66735.1 - 2.4e-12 47.1 8.6 1.6e-06 28.8 1.8 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40_like PF17005.5 KFM66735.1 - 0.13 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 WD40-like domain ALS2CR8 PF15299.6 KFM66736.1 - 3e-13 50.2 0.2 3.3e-13 50.0 0.2 1.0 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 HTH_Tnp_Tc3_2 PF01498.18 KFM66737.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66737.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66737.1 - 1.7e-07 30.9 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66737.1 - 0.0023 17.7 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66737.1 - 0.024 14.8 0.4 0.082 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM66737.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain p450 PF00067.22 KFM66738.1 - 2.1e-22 79.5 0.2 2.3e-22 79.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.6 KFM66740.1 - 1.3e-09 38.0 0.0 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SAB PF04382.13 KFM66740.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 SAB domain BTB PF00651.31 KFM66741.1 - 1.2e-22 80.2 0.2 4.7e-21 75.1 0.0 2.0 1 1 1 2 2 2 2 BTB/POZ domain Guanylate_kin PF00625.21 KFM66744.1 - 6.9e-46 156.2 0.0 1.6e-45 155.0 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 KFM66744.1 - 1e-21 77.0 0.9 5.4e-12 45.9 0.8 2.9 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM66744.1 - 7.2e-20 70.6 0.1 5.1e-09 35.9 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFM66744.1 - 3.6e-12 46.4 0.3 0.00013 22.2 0.1 2.7 2 0 0 2 2 2 2 PDZ domain SH3_2 PF07653.17 KFM66744.1 - 1.1e-11 44.2 0.0 2.3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM66744.1 - 2.9e-05 23.6 0.0 7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain L27_N PF09060.10 KFM66744.1 - 0.00088 19.3 1.6 0.0027 17.7 0.5 2.4 2 0 0 2 2 2 1 L27_N Tricorn_PDZ PF14685.6 KFM66744.1 - 0.0018 18.2 0.2 1.6 8.7 0.1 3.2 3 1 0 3 3 3 2 Tricorn protease PDZ domain L27 PF02828.16 KFM66744.1 - 0.0023 17.7 2.0 0.011 15.5 0.1 2.9 3 0 0 3 3 3 1 L27 domain SH3_9 PF14604.6 KFM66744.1 - 0.0033 17.2 0.1 0.008 16.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_4 PF17816.1 KFM66744.1 - 0.016 15.6 0.9 1.1 9.7 0.0 3.6 3 0 0 3 3 3 0 PDZ domain NIF PF03031.18 KFM66745.1 - 1.3e-36 125.7 0.0 1.7e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EIIBC-GUT_N PF03612.14 KFM66746.1 - 0.044 13.5 0.1 0.056 13.2 0.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ssl1 PF04056.14 KFM66747.1 - 5e-88 294.0 0.1 6.7e-88 293.6 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KFM66747.1 - 4.4e-12 46.0 16.3 4.4e-12 46.0 16.3 3.6 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KFM66747.1 - 6.2e-12 46.1 0.0 1.1e-11 45.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Lipid_DES PF08557.10 KFM66747.1 - 0.12 11.9 0.6 0.26 10.8 0.6 1.5 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) zinc_ribbon_9 PF14369.6 KFM66747.1 - 1.8 8.9 15.4 2.8 8.3 1.7 3.9 3 0 0 3 3 3 0 zinc-ribbon DZR PF12773.7 KFM66747.1 - 3.2 7.9 20.9 4.4e+03 -2.2 21.0 3.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 KFM66747.1 - 7.9 6.4 22.8 0.24 11.3 9.0 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Chitin_bind_4 PF00379.23 KFM66748.1 - 3.1e-10 40.4 11.0 6.4e-10 39.4 11.0 1.6 1 0 0 1 1 1 1 Insect cuticle protein HTH_Tnp_Tc3_2 PF01498.18 KFM66749.1 - 1.8e-08 34.5 0.1 2.3e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Transposase ABC_tran_CTD PF16326.5 KFM66750.1 - 0.016 15.5 5.3 0.016 15.5 5.3 8.3 6 2 3 9 9 9 0 ABC transporter C-terminal domain AAA_23 PF13476.6 KFM66751.1 - 1.3e-16 61.7 0.9 1.5e-16 61.5 0.9 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFM66751.1 - 2.2e-14 53.4 0.6 2.5e-14 53.2 0.6 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KFM66751.1 - 9.6e-09 35.4 0.7 1e-08 35.3 0.7 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFM66751.1 - 0.00036 20.2 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KFM66751.1 - 0.00086 19.2 0.3 0.00087 19.2 0.3 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Zot PF05707.12 KFM66751.1 - 0.04 13.6 0.1 0.048 13.3 0.1 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Arteri_Gl PF00951.18 KFM66751.1 - 0.041 13.7 0.1 0.052 13.4 0.1 1.1 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein ABC_tran PF00005.27 KFM66751.1 - 0.045 14.3 0.1 0.055 14.0 0.1 1.4 1 0 0 1 1 1 0 ABC transporter AAA_27 PF13514.6 KFM66751.1 - 0.064 12.8 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM66751.1 - 0.07 13.1 0.1 0.22 11.4 0.1 1.8 1 1 1 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 KFM66751.1 - 0.099 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase HECT PF00632.25 KFM66753.1 - 3.8e-101 338.6 0.0 5.1e-101 338.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFM66753.1 - 4.5e-19 68.2 4.7 3.6e-10 39.8 0.3 2.6 2 0 0 2 2 2 2 WW domain LicD PF04991.13 KFM66755.1 - 0.093 12.8 0.0 0.76 9.9 0.0 2.0 1 1 0 2 2 2 0 LicD family Pkinase PF00069.25 KFM66757.1 - 8.1e-52 176.2 0.0 1.8e-51 175.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM66757.1 - 5.9e-25 88.0 0.0 1.1e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KFM66757.1 - 0.024 14.2 0.2 0.074 12.6 0.1 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 KFM66757.1 - 0.04 13.8 0.0 0.8 9.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family CSN7a_helixI PF18392.1 KFM66758.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Cadherin PF00028.17 KFM66759.1 - 3.5e-06 27.3 0.0 1.1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Cadherin domain SQAPI PF16845.5 KFM66759.1 - 0.042 14.2 0.0 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Aspartic acid proteinase inhibitor ELO PF01151.18 KFM66760.1 - 6.8e-48 163.4 19.8 8.2e-48 163.1 19.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RVT_1 PF00078.27 KFM66762.1 - 1.7e-46 158.5 0.1 2.3e-46 158.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2737 PF10930.8 KFM66762.1 - 0.0094 15.5 0.1 0.027 14.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2737) DUF4371 PF14291.6 KFM66763.1 - 1.5e-30 106.6 0.5 2.9e-30 105.7 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM66763.1 - 1.9e-09 37.2 0.2 7.4e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM66763.1 - 0.034 13.1 7.3 0.054 12.5 0.3 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MAT1 PF06391.13 KFM66763.1 - 2.3 8.0 7.7 2.4 7.9 2.0 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 HTH_Tnp_Tc3_2 PF01498.18 KFM66764.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66764.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66766.1 - 4.3e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66766.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66766.1 - 1.7e-06 27.6 1.1 6.2e-06 25.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66766.1 - 0.0046 16.7 0.6 0.013 15.3 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66766.1 - 9.3 7.0 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 KFM66767.1 - 2.7e-76 248.8 69.1 2.7e-09 37.0 0.3 10.8 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66767.1 - 5.9e-59 193.4 87.1 6.1e-07 29.6 0.7 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66767.1 - 5.1e-41 135.8 78.7 0.00019 22.0 0.3 10.2 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM66767.1 - 7.3e-28 96.1 79.4 7.2e-05 23.0 1.6 10.6 10 1 0 10 10 10 10 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM66767.1 - 2e-24 85.1 63.4 1.8e-05 24.6 1.0 10.2 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM66767.1 - 2e-15 56.6 66.0 0.0044 17.3 0.4 10.4 8 2 2 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM66767.1 - 2.4e-15 56.0 53.6 0.022 14.5 0.7 10.3 10 0 0 10 10 10 8 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM66767.1 - 3.3e-08 33.3 35.3 0.031 14.2 0.4 6.3 3 1 4 7 7 7 4 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM66767.1 - 1.6e-05 25.0 11.4 0.17 12.0 2.1 4.9 1 1 5 6 6 6 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF2256 PF10013.9 KFM66767.1 - 2.3e-05 24.4 35.5 7.7 6.7 0.1 9.8 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFM66767.1 - 4.8e-05 23.1 32.3 19 5.3 0.0 9.5 9 0 0 9 9 9 0 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM66767.1 - 0.00014 21.8 44.5 2.4 8.3 0.4 9.8 6 4 4 10 10 10 2 Sec23/Sec24 zinc finger zf-BED PF02892.15 KFM66767.1 - 0.00026 20.9 75.0 0.14 12.2 1.6 9.9 1 1 9 10 10 10 4 BED zinc finger HNH_5 PF14279.6 KFM66767.1 - 0.0011 18.8 49.5 0.028 14.3 2.1 8.4 6 4 0 6 6 6 2 HNH endonuclease GAGA PF09237.11 KFM66767.1 - 0.0013 18.5 30.5 0.36 10.7 0.1 8.5 1 1 9 10 10 10 2 GAGA factor BolA PF01722.18 KFM66767.1 - 0.0037 17.5 16.1 0.37 11.1 0.9 5.8 1 1 5 6 6 6 1 BolA-like protein zf-C2H2_9 PF16293.5 KFM66767.1 - 0.0038 17.0 39.2 4.4 7.2 0.1 9.4 2 2 8 10 10 10 1 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM66767.1 - 0.0043 17.8 38.2 1.1 10.0 1.0 5.3 1 1 4 7 7 7 4 zinc-ribbon family zf-MYST PF17772.1 KFM66767.1 - 0.013 15.1 46.1 5.8 6.6 0.1 9.8 3 3 7 10 10 10 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 KFM66767.1 - 0.013 15.8 62.2 0.38 11.1 1.0 9.2 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM66767.1 - 0.021 14.4 42.5 5.5 6.7 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 KFM66767.1 - 0.024 14.5 53.7 2.9 7.8 0.8 9.4 1 1 8 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHCC PF10276.9 KFM66767.1 - 0.047 13.7 15.6 59 3.8 0.0 8.0 10 0 0 10 10 10 0 Zinc-finger domain zf-RRPl_C4 PF17026.5 KFM66767.1 - 0.065 13.4 38.0 4.7 7.4 2.8 4.5 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 KFM66767.1 - 0.11 12.6 31.9 3.2 8.0 1.6 6.7 2 2 4 6 6 6 0 Zinc ribbon domain C5HCH PF17982.1 KFM66767.1 - 0.88 9.8 46.9 17 5.6 1.2 9.5 4 3 6 10 10 10 0 NSD Cys-His rich domain YyzF PF14116.6 KFM66767.1 - 0.92 9.6 27.6 22 5.2 0.1 8.9 10 0 0 10 10 10 0 YyzF-like protein FYVE PF01363.21 KFM66767.1 - 0.97 9.6 53.7 3.1 8.0 10.2 6.4 1 1 2 3 3 2 0 FYVE zinc finger XPA_N PF01286.18 KFM66767.1 - 1.6 8.8 35.3 32 4.7 0.1 9.6 10 0 0 10 10 10 0 XPA protein N-terminal TRAF6_Z2 PF18048.1 KFM66767.1 - 1.6 8.9 52.2 0.31 11.2 1.0 9.5 10 0 0 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 zf-H2C2_2 PF13465.6 KFM66768.1 - 7.4e-71 231.7 41.3 3.8e-09 36.6 0.3 9.1 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66768.1 - 6.8e-42 139.6 62.8 7.6e-06 26.1 1.5 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66768.1 - 4.1e-34 114.3 59.6 0.00013 22.5 1.1 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM66768.1 - 2.2e-21 75.3 38.1 0.0091 15.7 0.0 8.4 8 0 0 8 8 8 6 C2H2-type zinc-finger domain zf-met PF12874.7 KFM66768.1 - 8.4e-13 48.3 61.5 0.0013 19.0 1.9 8.3 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM66768.1 - 5.3e-12 45.4 54.2 0.023 14.7 0.7 8.9 8 1 0 8 8 8 6 C2H2-type zinc finger BolA PF01722.18 KFM66768.1 - 6.9e-09 35.9 7.1 1.7 9.0 0.0 5.9 1 1 3 5 5 5 3 BolA-like protein zf-C2HC_2 PF13913.6 KFM66768.1 - 1.6e-07 31.0 29.7 2.1 8.3 0.1 8.5 8 0 0 8 8 8 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFM66768.1 - 3.7e-06 27.1 45.5 0.005 17.1 0.7 8.3 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding FYVE PF01363.21 KFM66768.1 - 4.1e-05 23.6 44.7 0.023 14.8 9.7 4.7 1 1 3 4 4 4 3 FYVE zinc finger ADK_lid PF05191.14 KFM66768.1 - 5.7e-05 23.0 21.2 0.14 12.2 1.1 5.7 2 1 4 6 6 6 2 Adenylate kinase, active site lid GAGA PF09237.11 KFM66768.1 - 6.1e-05 22.7 20.0 0.47 10.3 0.1 6.2 1 1 6 7 7 7 3 GAGA factor TRAF6_Z2 PF18048.1 KFM66768.1 - 6.7e-05 22.9 43.7 0.92 9.7 0.8 8.3 8 0 0 8 8 8 3 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_15 PF17032.5 KFM66768.1 - 8.4e-05 23.3 26.8 0.25 12.1 0.7 4.1 4 0 0 4 4 4 4 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 KFM66768.1 - 8.7e-05 22.5 25.7 1.1 9.4 0.1 8.1 7 1 1 8 8 8 1 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 KFM66768.1 - 9.3e-05 22.1 42.9 0.4 10.5 0.2 7.6 8 0 0 8 8 8 5 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFM66768.1 - 0.00021 21.1 33.6 3 7.8 0.1 7.7 1 1 7 8 8 8 3 C2H2 type zinc-finger (1 copy) Tox-HNH-HHH PF15637.6 KFM66768.1 - 0.0005 20.2 1.1 9.5 6.4 0.0 3.8 1 1 2 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Herpes_ORF11 PF04797.13 KFM66768.1 - 0.004 16.0 0.2 1.3 7.7 0.1 2.3 1 1 1 2 2 2 2 Herpesvirus dUTPase protein DUF5502 PF17606.2 KFM66768.1 - 0.0047 17.6 1.5 38 5.1 0.0 3.7 2 2 1 3 3 3 0 Family of unknown function (DUF5502) C5HCH PF17982.1 KFM66768.1 - 0.0051 16.9 38.9 9.1 6.5 1.5 8.1 5 2 2 8 8 8 0 NSD Cys-His rich domain PUF PF00806.19 KFM66768.1 - 0.0055 16.3 0.9 21 5.0 0.0 5.0 6 0 0 6 6 6 0 Pumilio-family RNA binding repeat YyzF PF14116.6 KFM66768.1 - 0.0063 16.5 18.7 32 4.7 0.1 7.7 8 0 0 8 8 8 0 YyzF-like protein Prok-RING_1 PF14446.6 KFM66768.1 - 0.044 13.7 36.1 7.4 6.6 0.1 8.0 8 0 0 8 8 8 0 Prokaryotic RING finger family 1 Adhesin_P1 PF03257.13 KFM66768.1 - 0.067 13.7 0.0 56 4.4 0.0 3.7 1 1 2 3 3 3 0 Mycoplasma adhesin P1 zf-MYST PF17772.1 KFM66768.1 - 0.087 12.5 31.7 2.7 7.6 0.3 7.6 4 2 4 8 8 8 0 MYST family zinc finger domain SPARC_Ca_bdg PF10591.9 KFM66768.1 - 0.1 12.9 15.1 0.61 10.4 0.2 4.6 2 2 4 6 6 6 0 Secreted protein acidic and rich in cysteine Ca binding region HNH_5 PF14279.6 KFM66768.1 - 0.31 10.9 48.5 5.4 6.9 0.2 7.5 5 3 2 7 7 7 0 HNH endonuclease DUF952 PF06108.12 KFM66768.1 - 0.36 10.8 1.5 30 4.7 0.1 3.7 2 1 1 4 4 4 0 Protein of unknown function (DUF952) zf-HIT PF04438.16 KFM66768.1 - 0.63 10.0 41.3 6.7 6.7 0.6 8.1 8 0 0 8 8 8 0 HIT zinc finger zf-C2H2_3rep PF18868.1 KFM66768.1 - 0.66 10.7 31.9 12 6.6 0.4 6.6 1 1 3 6 6 6 0 Zinc finger C2H2-type, 3 repeats Zf_RING PF16744.5 KFM66768.1 - 1.6 8.9 37.8 4.1 7.6 0.8 7.6 1 1 5 6 6 6 0 KIAA1045 RING finger zf-DBF PF07535.12 KFM66768.1 - 2.1 8.5 34.0 11 6.2 0.6 7.7 8 0 0 8 8 8 0 DBF zinc finger zf_UBZ PF18439.1 KFM66768.1 - 3.2 7.4 39.6 13 5.5 0.8 8.1 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM66768.1 - 4.4 7.5 31.2 0.71 10.0 0.9 4.0 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type Viral_cys_rich PF08008.12 KFM66768.1 - 6.4 6.9 9.5 6.4 6.9 0.4 4.1 1 1 3 5 5 5 0 Viral cysteine rich InaF-motif PF15018.6 KFM66769.1 - 2.1e-18 65.9 3.6 2.8e-18 65.5 3.6 1.2 1 0 0 1 1 1 1 TRP-interacting helix RRM_5 PF13893.6 KFM66770.1 - 4.8e-41 139.3 0.0 7.1e-41 138.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFM66770.1 - 1e-06 28.5 0.1 0.00023 20.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Carbpep_Y_N PF05388.11 KFM66770.1 - 0.032 14.8 0.1 0.056 14.0 0.1 1.3 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide DUF825 PF05695.12 KFM66770.1 - 0.12 9.5 0.0 0.15 9.2 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) RRM_occluded PF16842.5 KFM66770.1 - 0.17 11.7 0.0 0.43 10.5 0.0 1.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_8 PF11835.8 KFM66771.1 - 0.067 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain Nup88 PF10168.9 KFM66772.1 - 2.8e-180 600.6 9.4 3.4e-180 600.4 9.4 1.0 1 0 0 1 1 1 1 Nuclear pore component Bombinin PF05298.11 KFM66772.1 - 0.039 13.6 0.2 0.11 12.2 0.2 1.7 1 0 0 1 1 1 0 Bombinin T2SSF PF00482.23 KFM66772.1 - 0.049 13.6 2.1 0.15 12.0 0.8 2.3 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F DUF2524 PF10732.9 KFM66772.1 - 5.7 7.3 15.3 1.5 9.2 8.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Exonuc_VII_L PF02601.15 KFM66772.1 - 7.7 6.0 22.5 8.1e+02 -0.6 22.5 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit zf-RanBP PF00641.18 KFM66773.1 - 0.003 16.8 5.9 0.0067 15.7 5.9 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Transglut_C PF00927.22 KFM66773.1 - 0.053 13.7 0.2 7.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain PIN_4 PF13638.6 KFM66773.1 - 0.16 12.3 1.2 0.99 9.7 0.8 2.3 2 0 0 2 2 2 0 PIN domain CCDC-167 PF15188.6 KFM66773.1 - 0.43 11.0 7.2 0.81 10.1 5.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DivIC PF04977.15 KFM66773.1 - 2.9 7.7 7.9 3.5 7.5 3.4 2.6 2 0 0 2 2 2 0 Septum formation initiator HTH_Tnp_Tc3_2 PF01498.18 KFM66774.1 - 2.2e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66774.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66775.1 - 5e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66775.1 - 5.3e-14 52.2 0.0 9.2e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66775.1 - 4.3e-08 32.8 0.8 7.3e-07 28.9 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66775.1 - 0.0027 17.5 0.6 0.0078 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66775.1 - 0.079 13.1 3.6 0.094 12.9 0.4 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM66775.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM66776.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF659 PF04937.15 KFM66777.1 - 0.0005 20.0 0.5 0.00074 19.4 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM66777.1 - 0.0022 17.7 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF4371 PF14291.6 KFM66778.1 - 4.9e-10 39.4 0.0 1.6e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM66778.1 - 0.0033 17.0 0.8 0.0033 17.0 0.8 2.3 2 1 0 2 2 2 1 Zinc-finger C2H2-type DDE_3 PF13358.6 KFM66779.1 - 5.1e-16 58.7 0.1 4.9e-15 55.5 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66779.1 - 8.3e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM66779.1 - 0.0017 19.0 1.6 0.0017 19.0 1.6 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM66779.1 - 0.0033 17.2 0.1 0.13 12.1 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66779.1 - 0.018 15.2 0.1 0.072 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM66779.1 - 0.043 13.8 0.4 0.043 13.8 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix zf-C4 PF00105.18 KFM66780.1 - 5.4e-22 78.0 16.5 9e-22 77.3 16.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFM66780.1 - 7.8e-13 48.5 0.3 1.7e-12 47.4 0.3 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ras PF00071.22 KFM66782.1 - 3e-55 186.2 0.0 3.4e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM66782.1 - 3.9e-35 120.7 0.0 6.4e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM66782.1 - 2.1e-13 50.1 0.0 2.5e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFM66782.1 - 2.1e-06 27.8 0.1 0.034 14.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFM66782.1 - 3.3e-05 24.0 0.0 4.9e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.14 KFM66782.1 - 0.00012 22.1 0.0 0.00057 19.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 KFM66782.1 - 0.00016 21.2 0.0 0.003 17.1 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFM66782.1 - 0.00025 20.5 0.0 0.00028 20.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM66782.1 - 0.014 14.9 0.0 0.02 14.3 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KFM66782.1 - 0.015 15.6 0.0 0.15 12.3 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFM66782.1 - 0.018 15.4 0.1 0.018 15.4 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFM66782.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFM66782.1 - 0.035 13.8 0.0 0.048 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KFM66782.1 - 0.035 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KFM66782.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.5 2 0 0 2 2 2 0 NACHT domain PRK PF00485.18 KFM66782.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 KFM66782.1 - 0.095 13.2 0.0 0.69 10.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 KFM66782.1 - 0.1 12.6 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 Dynamin family G-alpha PF00503.20 KFM66782.1 - 0.1 11.7 0.1 0.9 8.6 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit CBM_21 PF03370.13 KFM66784.1 - 2.1e-23 82.7 0.8 3.9e-23 81.8 0.8 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFM66784.1 - 2.4e-12 47.3 0.9 5.8e-12 46.0 0.9 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Integrin_beta PF00362.18 KFM66785.1 - 4.9e-109 363.7 0.3 9.7e-109 362.8 0.0 1.6 2 0 0 2 2 2 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 KFM66785.1 - 8e-22 76.7 0.1 1.5e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain I-EGF_1 PF18372.1 KFM66785.1 - 4.9e-07 29.7 77.0 8.5e-06 25.8 9.5 5.9 5 1 0 5 5 5 3 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFM66785.1 - 5.7e-06 26.6 61.8 0.00042 20.6 14.9 6.6 6 1 1 7 7 7 3 EGF-like domain Geminin PF07412.12 KFM66786.1 - 8.8e-10 38.7 1.1 8.8e-10 38.7 1.1 2.5 1 1 0 2 2 2 1 Geminin MMR1 PF08505.10 KFM66786.1 - 1.6 8.9 16.1 1.8 8.8 15.5 1.4 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GAGA_bind PF06217.12 KFM66786.1 - 7.5 6.7 17.1 5 7.3 15.7 1.4 1 1 0 1 1 1 0 GAGA binding protein-like family WD40 PF00400.32 KFM66787.1 - 1.1e-43 146.4 16.0 5.4e-09 36.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 KFM66787.1 - 5.3e-15 54.7 0.9 5.3e-15 54.7 0.9 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KFM66787.1 - 4.3e-10 39.8 0.1 0.0057 16.9 0.0 4.9 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM66787.1 - 2.1e-09 36.8 1.0 0.0028 16.7 0.6 5.5 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFM66787.1 - 3.4e-06 27.1 0.0 0.029 14.2 0.0 3.4 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFM66787.1 - 0.0024 16.6 5.7 0.71 8.4 0.1 4.9 3 2 2 5 5 5 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KFM66787.1 - 0.034 13.5 0.0 3.8 6.7 0.0 3.1 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal HPS3_N PF14761.6 KFM66787.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 KFM66787.1 - 0.19 11.0 0.0 1.4 8.2 0.0 2.3 2 1 1 3 3 3 0 WD40-like domain Aldedh PF00171.22 KFM66788.1 - 1.5e-182 607.3 0.0 1.7e-182 607.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFM66788.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) HTH_Tnp_Tc3_2 PF01498.18 KFM66789.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66789.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66789.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66789.1 - 0.0024 17.6 0.6 0.0072 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66790.1 - 5.1e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66790.1 - 1.2e-13 51.0 0.0 2.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66790.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66790.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66790.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66791.1 - 5e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66791.1 - 1.3e-13 50.9 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66791.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66791.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66791.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66792.1 - 5.3e-16 58.6 2.2 5.3e-16 58.6 2.2 2.0 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM66792.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66792.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66792.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66792.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain WD40 PF00400.32 KFM66793.1 - 0.00086 20.1 2.6 14 6.7 0.0 4.9 6 0 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KFM66793.1 - 0.079 13.0 0.2 0.37 10.8 0.1 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PB1-F2 PF11986.8 KFM66793.1 - 0.096 12.9 0.2 3.6 7.9 0.1 2.7 3 0 0 3 3 3 0 Influenza A Proapoptotic protein Cytadhesin_P30 PF07271.11 KFM66793.1 - 0.28 10.7 0.0 0.41 10.2 0.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF5067 PF16729.5 KFM66794.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) WD40_like PF17005.5 KFM66795.1 - 0.098 12.0 1.5 1.2 8.5 1.4 2.4 1 1 1 2 2 2 0 WD40-like domain CPSF_A PF03178.15 KFM66795.1 - 0.1 11.9 0.1 0.65 9.2 0.0 2.0 2 0 0 2 2 2 0 CPSF A subunit region Coatomer_WDAD PF04053.14 KFM66796.1 - 0.033 13.2 0.1 0.078 12.0 0.1 1.5 1 1 1 2 2 2 0 Coatomer WD associated region CPSF_A PF03178.15 KFM66796.1 - 0.048 13.0 0.1 0.052 12.9 0.1 1.2 1 1 0 1 1 1 0 CPSF A subunit region RRM_1 PF00076.22 KFM66797.1 - 1e-18 66.9 0.1 1.8e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM66797.1 - 0.079 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Med24_N PF11277.8 KFM66798.1 - 0 1139.4 4.3 0 1139.3 4.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal zf-C2H2_4 PF13894.6 KFM66799.1 - 8e-05 23.2 18.6 0.01 16.6 1.8 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM66799.1 - 0.00015 22.0 19.9 0.0085 16.5 2.4 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM66799.1 - 0.0044 17.3 2.2 0.0044 17.3 2.2 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFM66799.1 - 0.0056 17.1 0.4 0.0056 17.1 0.4 3.0 3 1 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KFM66799.1 - 0.029 14.8 9.7 0.43 11.0 2.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM66799.1 - 0.031 14.0 4.9 0.031 14.0 4.9 2.9 2 1 1 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM66799.1 - 0.33 10.9 9.6 2.7 8.0 1.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Spt46 PF17734.1 KFM66799.1 - 0.65 9.8 4.2 0.73 9.6 4.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 zf-C2HE PF16278.5 KFM66799.1 - 1 9.8 9.6 3.7e+02 1.7 9.6 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 KFM66800.1 - 4.9e-11 42.5 20.8 4.2e-08 33.3 0.5 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66800.1 - 1.6e-10 40.8 29.3 0.00082 19.7 1.2 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66800.1 - 2.9e-10 40.1 27.8 0.0025 18.5 1.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFM66800.1 - 4.8e-08 33.1 22.9 0.0033 17.8 0.9 4.3 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM66800.1 - 3.8e-07 30.2 20.9 0.0013 19.0 0.8 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM66800.1 - 1.4e-06 28.0 3.4 1.4e-06 28.0 3.4 2.5 4 0 0 4 4 3 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM66800.1 - 0.0012 18.8 0.4 0.0012 18.8 0.4 4.7 5 1 0 5 5 4 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM66800.1 - 0.014 15.3 1.2 0.014 15.3 1.2 3.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM66800.1 - 0.038 14.1 7.6 0.92 9.7 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 KFM66800.1 - 0.052 13.3 0.7 0.052 13.3 0.7 4.2 4 1 0 4 4 4 0 zinc-finger C2H2-type BolA PF01722.18 KFM66800.1 - 0.057 13.7 0.7 2 8.7 0.7 2.4 1 1 0 1 1 1 0 BolA-like protein zf-C2H2_2 PF12756.7 KFM66800.1 - 0.11 12.9 18.1 0.25 11.7 0.9 3.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 KFM66800.1 - 0.21 11.7 5.3 5.6 7.0 0.1 3.5 2 1 2 4 4 4 0 CpXC protein Zn-ribbon_8 PF09723.10 KFM66800.1 - 0.26 11.4 10.7 3.2 7.9 0.9 4.0 3 1 1 4 4 4 0 Zinc ribbon domain zf_UBZ PF18439.1 KFM66800.1 - 0.59 9.8 11.6 1.8 8.2 0.2 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger HNH PF01844.23 KFM66800.1 - 0.67 10.2 12.2 7.7 6.8 2.2 3.5 3 0 0 3 3 3 0 HNH endonuclease Zn_ribbon_SprT PF17283.2 KFM66800.1 - 1.2 9.1 18.3 0.23 11.4 3.7 3.4 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zf-nanos PF05741.13 KFM66800.1 - 1.4 9.3 14.3 2.2 8.6 2.9 4.0 2 2 0 2 2 2 0 Nanos RNA binding domain DUF3449 PF11931.8 KFM66800.1 - 2.5 7.9 10.7 1 9.1 0.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3449) Zn_ribbon_recom PF13408.6 KFM66800.1 - 4.1 8.0 12.1 25 5.5 0.1 3.2 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain C1_2 PF03107.16 KFM66800.1 - 4.1 7.8 19.2 1.3 9.4 2.0 4.0 2 1 2 4 4 4 0 C1 domain DUF3330 PF11809.8 KFM66802.1 - 0.012 15.7 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Ras PF00071.22 KFM66805.1 - 1.2e-14 54.3 0.3 1.5e-14 54.0 0.3 1.1 1 0 0 1 1 1 1 Ras family DUF2315 PF10231.9 KFM66805.1 - 0.006 16.7 2.5 0.0071 16.4 2.5 1.0 1 0 0 1 1 1 1 Apoptogenic protein 1 ArgoMid PF16487.5 KFM66805.1 - 0.011 16.0 0.2 0.014 15.6 0.2 1.1 1 0 0 1 1 1 0 Mid domain of argonaute MeaB PF03308.16 KFM66805.1 - 0.13 11.2 0.2 0.14 11.1 0.2 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DDE_3 PF13358.6 KFM66807.1 - 0.042 13.6 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease HLH PF00010.26 KFM66808.1 - 1.5e-10 40.9 2.6 1.8e-10 40.6 1.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1666 PF07891.12 KFM66808.1 - 0.018 14.7 0.9 0.028 14.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) HTH_Tnp_Tc3_2 PF01498.18 KFM66809.1 - 2.4e-18 66.1 4.0 4.3e-18 65.3 1.7 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66809.1 - 7e-14 51.8 0.0 4.7e-13 49.1 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM66809.1 - 1.1e-07 31.8 0.4 7e-05 22.8 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM66809.1 - 1.8e-07 30.7 2.5 3e-06 26.9 0.0 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66809.1 - 2e-07 31.5 3.6 2.4e-07 31.3 1.5 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66809.1 - 1.3e-06 28.4 4.0 5e-05 23.3 0.2 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM66809.1 - 3e-06 27.1 1.1 4.3e-05 23.5 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM66809.1 - 7e-05 22.6 0.5 0.00053 19.8 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM66809.1 - 0.00037 20.4 0.6 0.0059 16.6 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_17 PF12728.7 KFM66809.1 - 0.0023 18.1 0.1 0.42 10.8 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.7 KFM66809.1 - 0.0038 17.3 0.0 0.16 12.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM66809.1 - 0.0098 15.4 0.1 0.052 13.1 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 GntR PF00392.21 KFM66809.1 - 0.019 14.6 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_30 PF13556.6 KFM66809.1 - 0.024 14.4 3.1 0.2 11.5 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_22 PF13309.6 KFM66809.1 - 0.027 14.6 0.1 8.7 6.5 0.0 2.6 2 0 0 2 2 2 0 HTH domain CENP-B_N PF04218.13 KFM66809.1 - 0.041 13.5 0.3 0.11 12.2 0.1 1.8 2 0 0 2 2 1 0 CENP-B N-terminal DNA-binding domain TrmB PF01978.19 KFM66809.1 - 0.053 13.4 0.0 1.7 8.5 0.0 2.3 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB GerE PF00196.19 KFM66809.1 - 0.054 13.1 0.1 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_21 PF13276.6 KFM66809.1 - 0.12 12.6 0.9 1.6 8.9 0.9 2.5 1 1 2 3 3 3 0 HTH-like domain HTH_Tnp_ISL3 PF13542.6 KFM66809.1 - 0.13 11.7 1.1 2.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 NUMOD1 PF07453.13 KFM66809.1 - 0.14 12.5 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 NUMOD1 domain Rrf2 PF02082.20 KFM66809.1 - 0.17 12.3 0.0 0.48 10.8 0.0 1.7 1 1 1 2 2 2 0 Transcriptional regulator HTH_11 PF08279.12 KFM66809.1 - 0.18 11.8 0.5 17 5.4 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_26 PF13443.6 KFM66809.1 - 0.18 12.3 0.5 3.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_8 PF02954.19 KFM66809.1 - 0.19 11.5 2.4 3.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family HTH_24 PF13412.6 KFM66809.1 - 0.21 11.2 1.4 2.9 7.5 0.0 2.5 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 KFM66809.1 - 0.24 11.5 1.5 7.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.6 KFM66809.1 - 0.36 10.6 3.6 0.8 9.5 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain cNMP_binding PF00027.29 KFM66810.1 - 1.8e-45 152.9 0.1 6.3e-23 80.7 0.0 2.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KFM66810.1 - 6.5e-15 54.5 0.4 1.2e-14 53.6 0.4 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 KFM66810.1 - 0.0013 18.3 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif ADH_zinc_N_2 PF13602.6 KFM66811.1 - 3.6e-08 34.5 0.0 4.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cytochrom_B558a PF05038.13 KFM66811.1 - 0.39 10.3 1.0 0.53 9.8 1.0 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit ADH_N PF08240.12 KFM66812.1 - 1.4e-13 50.7 0.0 3.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFM66812.1 - 0.0027 18.8 0.0 0.0065 17.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KFM66812.1 - 0.0065 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DapB_N PF01113.20 KFM66812.1 - 0.089 12.9 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Nic96 PF04097.14 KFM66813.1 - 3.7e-183 610.4 1.8 4.6e-183 610.1 1.8 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nup84_Nup100 PF04121.13 KFM66813.1 - 0.0001 20.6 0.0 0.00022 19.5 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Vps39_1 PF10366.9 KFM66813.1 - 0.012 15.9 1.5 0.9 9.9 0.1 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DUF4085 PF13315.6 KFM66813.1 - 0.02 14.5 0.8 0.02 14.5 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4085) NPV_P10 PF05531.12 KFM66813.1 - 0.06 13.8 0.9 0.33 11.4 0.0 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ANAPC3 PF12895.7 KFM66813.1 - 0.55 10.5 4.0 1.5 9.1 0.3 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TSNAXIP1_N PF15739.5 KFM66815.1 - 0.0046 17.3 5.2 0.0094 16.3 5.2 1.6 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus Paramyxo_ncap PF00973.19 KFM66815.1 - 0.012 14.5 0.9 0.014 14.4 0.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Tektin PF03148.14 KFM66815.1 - 0.017 13.9 6.3 0.03 13.1 6.3 1.4 1 0 0 1 1 1 0 Tektin family SASP PF00269.20 KFM66815.1 - 0.029 14.4 0.8 0.029 14.4 0.8 2.2 3 0 0 3 3 3 0 Small, acid-soluble spore proteins, alpha/beta type NEMO PF11577.8 KFM66815.1 - 0.063 13.3 5.6 0.54 10.3 5.6 2.4 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO ApoLp-III PF07464.11 KFM66815.1 - 0.16 12.0 5.6 0.75 9.9 5.4 2.1 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 KFM66815.1 - 0.16 12.6 2.5 0.82 10.3 2.4 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PEP-utilisers_N PF05524.13 KFM66815.1 - 1.3 9.2 8.1 0.88 9.8 4.8 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal YtxH PF12732.7 KFM66815.1 - 3.3 8.3 8.3 10 6.7 0.6 2.4 1 1 1 2 2 2 0 YtxH-like protein Sec2p PF06428.11 KFM66815.1 - 6.7 6.8 12.9 13 5.8 0.2 3.1 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p OmpH PF03938.14 KFM66815.1 - 7 7.0 11.8 13 6.1 10.3 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) WD40 PF00400.32 KFM66816.1 - 1.3e-12 48.0 1.1 1.5e-05 25.6 0.3 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM66816.1 - 8.8e-06 25.9 0.0 0.02 15.2 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 KFM66816.1 - 0.023 14.3 0.1 0.058 13.0 0.1 1.6 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Thioredoxin PF00085.20 KFM66817.1 - 8e-09 35.4 0.0 8.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KFM66817.1 - 0.0029 17.6 0.0 0.0034 17.3 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KFM66817.1 - 0.0049 17.3 0.1 0.024 15.1 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM66817.1 - 0.0097 16.2 0.2 3.3 8.1 0.1 2.0 1 1 1 2 2 2 2 Thioredoxin-like DIM1 PF02966.16 KFM66817.1 - 0.026 14.3 0.1 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 OST3_OST6 PF04756.13 KFM66817.1 - 0.029 13.7 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KFM66817.1 - 0.046 13.8 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Glutaredoxin PF00462.24 KFM66818.1 - 3.3e-18 65.7 0.0 4.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 KFM66818.1 - 0.021 15.0 0.0 0.038 14.1 0.0 1.4 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Med26 PF08711.11 KFM66820.1 - 4.4e-15 55.4 0.0 1.5e-14 53.7 0.0 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain GET2 PF08690.10 KFM66820.1 - 4 7.0 12.9 0.67 9.6 6.4 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 Noelin-1 PF12308.8 KFM66820.1 - 4.2 7.4 9.2 0.78 9.8 1.0 2.8 3 1 0 3 3 3 0 Neurogenesis glycoprotein CxC2 PF18803.1 KFM66822.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases COMM_domain PF07258.14 KFM66823.1 - 0.004 17.2 0.2 0.0044 17.1 0.2 1.1 1 0 0 1 1 1 1 COMM domain Amidohydro_1 PF01979.20 KFM66825.1 - 2.6e-13 50.0 0.3 3.3e-13 49.7 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFM66825.1 - 1.7e-06 27.8 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family zf-CCHC PF00098.23 KFM66827.1 - 5.9e-06 26.1 1.4 8.1e-06 25.7 1.4 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM66827.1 - 0.0022 17.7 0.4 0.0036 17.0 0.4 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM66827.1 - 0.045 13.5 0.6 0.065 13.0 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2_2 PF13465.6 KFM66829.1 - 2.4e-77 252.1 112.7 3.2e-08 33.6 2.6 14.1 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66829.1 - 1.9e-49 163.4 132.6 4.2e-06 26.9 2.0 13.1 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66829.1 - 4.9e-45 148.3 120.3 0.00014 22.4 2.3 13.1 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM66829.1 - 3.4e-27 94.0 109.8 0.0058 17.0 3.5 13.5 12 1 1 13 13 13 13 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM66829.1 - 5.7e-26 90.0 98.8 0.00061 19.7 4.6 13.8 13 0 0 13 13 13 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM66829.1 - 2.9e-13 49.7 88.0 0.017 15.4 3.8 13.3 12 1 1 13 13 13 8 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM66829.1 - 3.8e-08 33.5 8.7 1.9 8.8 0.0 7.0 1 1 6 7 7 7 3 BolA-like protein zf-H2C2_5 PF13909.6 KFM66829.1 - 1.9e-05 24.3 106.4 0.0047 16.6 2.6 14.5 13 3 0 13 13 13 6 C2H2-type zinc-finger domain Complex1_49kDa PF00346.19 KFM66829.1 - 0.002 17.3 0.1 1.6 7.8 0.0 3.9 1 1 4 5 5 5 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-C2H2_11 PF16622.5 KFM66829.1 - 0.0048 16.6 0.7 0.0048 16.6 0.7 12.4 13 0 0 13 13 13 5 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFM66829.1 - 0.062 14.1 2.3 0.062 14.1 2.3 7.0 2 1 6 9 9 9 0 zinc-ribbon family IBD PF10416.9 KFM66829.1 - 1.4 8.9 7.8 0.14 12.2 0.6 3.0 2 2 1 3 3 3 0 Transcription-initiator DNA-binding domain IBD Scramblase PF03803.15 KFM66829.1 - 1.9 7.7 11.6 1.2 8.4 0.2 3.9 1 1 2 4 4 4 0 Scramblase zf-H2C2_2 PF13465.6 KFM66830.1 - 1.2e-45 151.9 42.5 3.2e-08 33.6 0.3 7.1 7 0 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66830.1 - 1.5e-29 100.8 51.4 7.6e-07 29.3 1.3 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66830.1 - 4.9e-25 86.0 46.1 0.00015 22.3 0.6 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFM66830.1 - 2.7e-14 53.0 42.8 0.0024 18.2 1.3 6.4 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM66830.1 - 7.9e-11 42.0 31.4 0.015 15.6 0.1 6.3 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM66830.1 - 2.9e-09 36.7 38.7 0.0036 17.3 0.2 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM66830.1 - 5e-08 32.6 43.4 0.02 14.6 1.4 7.8 8 0 0 8 8 8 5 C2H2-type zinc-finger domain BolA PF01722.18 KFM66830.1 - 5.3e-05 23.4 0.9 1.5 9.2 0.1 3.4 1 1 2 3 3 3 2 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM66830.1 - 0.0042 17.1 23.4 0.071 13.2 0.0 6.6 6 1 1 7 7 7 1 Sec23/Sec24 zinc finger Complex1_49kDa PF00346.19 KFM66830.1 - 0.016 14.3 0.1 1.1 8.2 0.0 2.2 1 1 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zinc_ribbon_15 PF17032.5 KFM66830.1 - 0.039 14.7 22.3 0.73 10.6 2.2 3.2 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_8 PF15909.5 KFM66830.1 - 0.059 13.7 23.9 1.5 9.1 0.7 3.8 1 1 2 3 3 3 0 C2H2-type zinc ribbon GNAT_C PF18164.1 KFM66830.1 - 0.24 11.1 1.1 0.44 10.3 0.5 1.7 1 1 1 2 2 2 0 GNAT-like C-terminal domain C1_4 PF07975.12 KFM66830.1 - 0.62 10.3 26.6 2.1 8.7 5.3 3.9 2 1 2 4 4 4 0 TFIIH C1-like domain zf-C2H2_2 PF12756.7 KFM66830.1 - 1.5 9.2 34.9 0.18 12.1 10.3 4.5 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Spt46 PF17734.1 KFM66830.1 - 2.6 7.8 14.1 6.1 6.6 6.2 3.4 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 ADK_lid PF05191.14 KFM66830.1 - 4.1 7.5 24.5 2.8 8.0 2.7 4.6 5 0 0 5 5 4 0 Adenylate kinase, active site lid zf-H2C2_2 PF13465.6 KFM66831.1 - 1.7e-41 138.8 52.5 2e-09 37.5 1.4 7.1 7 0 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM66831.1 - 1.1e-30 104.3 69.2 2.7e-06 27.5 1.2 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66831.1 - 3.8e-22 77.1 60.5 0.0004 21.0 0.7 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM66831.1 - 1.6e-16 60.1 56.8 0.0038 17.6 1.8 7.1 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM66831.1 - 6.7e-14 51.5 61.7 0.00034 20.5 5.1 7.5 7 1 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM66831.1 - 3.8e-07 30.2 55.3 7.8e-05 22.8 1.2 7.0 5 2 2 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM66831.1 - 2.3e-05 24.0 45.0 0.11 12.3 0.2 7.1 7 0 0 7 7 7 4 zinc-finger C2H2-type C1_1 PF00130.22 KFM66831.1 - 7.5e-05 22.5 34.7 0.02 14.8 0.6 6.0 3 1 3 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.7 KFM66831.1 - 0.0045 17.3 41.4 0.25 11.7 0.3 6.1 1 1 5 6 6 6 3 C2H2 type zinc-finger (2 copies) TRAF6_Z2 PF18048.1 KFM66831.1 - 0.012 15.7 16.5 1.1 9.4 0.8 4.8 5 0 0 5 5 4 0 TNF receptor-associated factor 6 zinc finger 2 Imm25 PF15564.6 KFM66831.1 - 0.029 14.3 0.0 4.1 7.3 0.0 2.6 2 1 1 3 3 3 0 Immunity protein 25 zinc_ribbon_15 PF17032.5 KFM66831.1 - 0.047 14.4 26.6 0.072 13.8 4.0 3.7 2 1 1 4 4 4 0 zinc-ribbon family BolA PF01722.18 KFM66831.1 - 0.17 12.2 10.4 3.8 7.8 2.4 3.9 2 1 2 4 4 4 0 BolA-like protein zf-C2HC_2 PF13913.6 KFM66831.1 - 1.8 8.5 33.8 0.77 9.7 0.2 6.3 7 0 0 7 7 6 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM66831.1 - 2.6 8.0 24.4 12 5.8 0.2 5.8 3 2 3 6 6 6 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM66831.1 - 3.1 8.0 38.4 1.2 9.3 10.9 4.3 1 1 2 3 3 3 0 FYVE zinc finger zf_UBZ PF18439.1 KFM66831.1 - 3.8 7.2 27.6 6.5 6.4 0.7 6.9 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM66831.1 - 6 6.6 15.0 3.2 7.4 0.4 4.7 5 0 0 5 5 5 0 MYST family zinc finger domain ADK_lid PF05191.14 KFM66831.1 - 6.6 6.8 27.8 0.25 11.4 1.4 4.5 4 1 1 5 5 5 0 Adenylate kinase, active site lid PPDK_N PF01326.19 KFM66832.1 - 2.8e-64 217.5 0.0 4.6e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 KFM66832.1 - 5.4e-21 74.1 0.2 1.2e-20 73.0 0.2 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Pox_G9-A16 PF03003.16 KFM66832.1 - 0.032 14.0 0.2 0.076 12.7 0.2 1.6 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 Exo_endo_phos_2 PF14529.6 KFM66833.1 - 4.1e-11 42.8 0.3 8e-11 41.8 0.3 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF2046 PF09755.9 KFM66835.1 - 2.2e-153 509.8 52.5 2.8e-153 509.5 52.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) HOCHOB PF17943.1 KFM66835.1 - 0.049 14.3 0.8 0.17 12.6 0.8 2.0 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox DUF3828 PF12883.7 KFM66835.1 - 2.9 8.3 6.8 1.5 9.2 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3828) CLP1_P PF16575.5 KFM66836.1 - 3.8e-67 225.7 0.0 6.1e-67 225.1 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KFM66836.1 - 4.6e-35 119.7 0.3 8.1e-35 118.9 0.3 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KFM66836.1 - 1.5e-31 109.2 0.1 2.3e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CbiA PF01656.23 KFM66836.1 - 0.00046 20.3 0.0 0.00083 19.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KFM66836.1 - 0.0025 18.2 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KFM66836.1 - 0.007 16.1 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFM66836.1 - 0.01 16.3 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFM66836.1 - 0.017 15.6 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM66836.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFM66836.1 - 0.026 14.4 0.0 0.06 13.2 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFM66836.1 - 0.028 14.4 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KFM66836.1 - 0.048 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_35 PF14516.6 KFM66836.1 - 0.054 12.3 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain TniB PF05621.11 KFM66836.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ATPase PF06745.13 KFM66836.1 - 0.094 12.0 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.23 KFM66836.1 - 0.1 12.7 0.0 0.39 10.8 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KFM66836.1 - 0.14 11.9 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ParB PF08775.10 KFM66838.1 - 0.035 14.6 2.9 0.043 14.3 2.9 1.2 1 0 0 1 1 1 0 ParB family DUF1664 PF07889.12 KFM66838.1 - 0.073 13.1 7.0 0.11 12.6 7.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 KFM66838.1 - 0.11 12.7 3.6 2.6 8.4 0.2 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain Cript PF10235.9 KFM66839.1 - 1.2e-07 32.2 0.1 1.2e-07 32.2 0.1 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT K_oxygenase PF13434.6 KFM66840.1 - 0.0019 17.4 0.0 0.002 17.3 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Methyltransf_25 PF13649.6 KFM66842.1 - 7.5e-18 65.0 0.0 1.7e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM66842.1 - 1.4e-16 60.7 0.0 2.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM66842.1 - 3.2e-15 56.4 0.0 5.2e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM66842.1 - 2e-14 54.0 0.0 4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM66842.1 - 4.1e-13 49.9 0.0 9.1e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM66842.1 - 1.2e-12 47.7 0.1 2.8e-12 46.5 0.1 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KFM66842.1 - 1.2e-05 25.2 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 KFM66842.1 - 0.00061 19.5 0.0 0.00098 18.8 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KFM66842.1 - 0.0012 18.4 0.0 0.0029 17.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KFM66842.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 KFM66842.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.17 KFM66842.1 - 0.033 13.7 0.0 0.079 12.4 0.0 1.8 1 1 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.16 KFM66842.1 - 0.049 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_9 PF08003.11 KFM66842.1 - 0.093 11.6 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) zf-CCHC PF00098.23 KFM66844.1 - 0.017 15.2 0.9 0.054 13.6 0.9 1.9 1 0 0 1 1 1 0 Zinc knuckle Histone_H2A_C PF16211.5 KFM66847.1 - 0.09 12.5 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 C-terminus of histone H2A PDZ PF00595.24 KFM66848.1 - 3.5e-27 94.6 1.9 6.5e-13 48.8 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM66848.1 - 4.3e-15 55.3 0.1 4.9e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Par3_HAL_N_term PF12053.8 KFM66849.1 - 3.8e-34 116.8 0.1 5.8e-34 116.2 0.1 1.3 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins zf-C2H2 PF00096.26 KFM66850.1 - 5.2e-16 58.1 84.7 0.00014 22.1 2.1 8.3 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM66850.1 - 9.5e-15 54.3 70.1 0.0012 19.1 2.8 9.4 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM66850.1 - 7.8e-14 51.2 80.7 0.0014 19.3 1.5 8.3 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM66850.1 - 3.2e-05 23.6 13.8 0.0002 21.1 4.1 8.0 7 2 1 8 8 8 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM66850.1 - 3.2e-05 24.1 38.7 0.13 12.5 1.4 6.7 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM66850.1 - 0.00021 21.2 23.1 0.0021 18.0 2.2 7.9 9 0 0 9 9 9 4 C2H2-type zinc finger zf-met PF12874.7 KFM66850.1 - 0.0004 20.7 34.6 0.018 15.4 1.3 6.5 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_7 PF15269.6 KFM66850.1 - 0.0079 16.3 4.9 0.046 13.8 0.6 4.6 3 1 1 5 5 5 2 Zinc-finger ARS2 PF04959.13 KFM66850.1 - 0.16 12.4 5.6 5.8 7.2 2.1 2.6 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Zn-ribbon_8 PF09723.10 KFM66850.1 - 3.4 7.8 34.3 3.9 7.7 3.1 6.7 4 2 3 7 7 7 0 Zinc ribbon domain HTH_Tnp_Tc3_2 PF01498.18 KFM66851.1 - 4.1e-17 62.2 1.2 1e-16 60.9 1.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66851.1 - 8.3e-15 54.8 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM66851.1 - 0.005 17.4 4.4 0.058 14.0 0.3 2.8 3 0 0 3 3 3 1 Homeodomain-like domain E1-E2_ATPase PF00122.20 KFM66853.1 - 2.5e-46 157.5 0.4 2.5e-46 157.5 0.4 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFM66853.1 - 2.8e-39 134.7 0.2 2.8e-39 134.7 0.2 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFM66853.1 - 1.6e-21 76.2 0.0 2.9e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFM66853.1 - 3.7e-21 76.4 0.0 5.3e-12 46.5 0.0 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFM66853.1 - 5e-16 58.1 0.0 9.2e-16 57.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFM66853.1 - 4.3e-06 26.7 1.3 0.0008 19.2 0.5 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM66853.1 - 0.021 15.3 0.1 0.14 12.6 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RVT_1 PF00078.27 KFM66854.1 - 0.037 13.5 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 KFM66855.1 - 3.9e-11 42.9 0.0 4.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ca_chan_IQ PF08763.11 KFM66855.1 - 0.18 12.0 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain zf-C4 PF00105.18 KFM66857.1 - 2.1e-31 108.2 12.2 2.1e-31 108.2 12.2 2.0 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFM66857.1 - 1.8e-24 86.5 0.4 2.9e-24 85.8 0.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF4710 PF15828.5 KFM66858.1 - 0.03 14.5 6.1 0.12 12.5 6.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4710) Y_phosphatase PF00102.27 KFM66860.1 - 8.7e-24 84.4 0.7 9.6e-24 84.2 0.7 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 KFM66861.1 - 1.7e-08 34.3 1.1 2.2e-08 34.0 0.3 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 KFM66862.1 - 2.8e-28 99.1 1.0 3.1e-28 98.9 1.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4371 PF14291.6 KFM66863.1 - 3.1e-05 23.7 0.1 3.2e-05 23.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) NUDIX_4 PF14815.6 KFM66866.1 - 2.7e-16 59.5 0.0 3.4e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain HCO3_cotransp PF00955.21 KFM66867.1 - 2.4e-49 168.5 5.2 2.6e-49 168.4 5.2 1.0 1 0 0 1 1 1 1 HCO3- transporter family MFS_MOT1 PF16983.5 KFM66867.1 - 0.49 10.8 6.1 1.4 9.4 6.1 1.8 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily HCO3_cotransp PF00955.21 KFM66868.1 - 3.7e-53 181.1 5.7 3.6e-32 111.9 0.0 2.0 1 1 1 2 2 2 2 HCO3- transporter family Cation_efflux PF01545.21 KFM66868.1 - 2.6 7.7 10.5 0.045 13.5 1.8 2.2 2 1 1 3 3 3 0 Cation efflux family Band_3_cyto PF07565.13 KFM66869.1 - 1.9e-59 201.7 0.1 2.2e-59 201.5 0.1 1.1 1 0 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 KFM66869.1 - 0.0058 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SUD-M PF11633.8 KFM66869.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 1 0 1 1 1 0 Single-stranded poly(A) binding domain DDE_3 PF13358.6 KFM66872.1 - 6e-16 58.5 0.1 6.5e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66872.1 - 8.6e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM66872.1 - 0.00078 20.0 1.5 0.00078 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM66872.1 - 0.0031 17.3 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66872.1 - 0.017 15.2 0.1 0.07 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM66872.1 - 0.038 14.0 0.4 0.038 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM66873.1 - 3.9e-16 59.1 3.4 5.2e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66873.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66873.1 - 2.5e-07 30.3 1.6 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66873.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66873.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM66874.1 - 2.8e-16 59.6 0.1 3e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66874.1 - 1.4e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase MULE PF10551.9 KFM66875.1 - 3.3e-16 59.5 0.4 8.5e-16 58.2 0.4 1.8 1 0 0 1 1 1 1 MULE transposase domain zf-H2C2_5 PF13909.6 KFM66875.1 - 0.0093 15.7 0.7 0.0093 15.7 0.7 2.5 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM66875.1 - 0.023 15.1 2.6 0.023 15.1 2.6 5.0 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_12 PF18658.1 KFM66875.1 - 1.3 8.7 7.5 0.11 12.1 0.4 2.9 2 1 1 3 3 3 0 Zinc-finger C2H2-type DNA_pol_B_2 PF03175.13 KFM66876.1 - 2.4e-08 33.3 1.9 1.1e-05 24.5 0.0 3.6 2 1 1 3 3 3 3 DNA polymerase type B, organellar and viral RNA_pol_Rpb2_6 PF00562.28 KFM66877.1 - 3.6e-119 398.3 0.1 8e-119 397.2 0.1 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 KFM66877.1 - 2.6e-21 75.8 0.1 5.3e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 KFM66877.1 - 3.7e-14 52.5 0.0 6.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain Desulfoferrod_N PF06397.12 KFM66877.1 - 0.09 12.4 0.3 0.21 11.3 0.3 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain RNA_pol_Rpb2_3 PF04565.16 KFM66878.1 - 7.9e-24 83.6 0.0 1e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 Gelsolin PF00626.22 KFM66879.1 - 0.0017 18.2 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 Gelsolin repeat RNA_pol_Rpb2_1 PF04563.15 KFM66880.1 - 4.8e-29 101.3 0.0 5.9e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFM66880.1 - 2.8e-08 33.6 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RWD PF05773.22 KFM66882.1 - 8.2e-10 39.0 0.8 5e-09 36.5 0.8 2.2 1 1 0 1 1 1 1 RWD domain DUF1115 PF06544.12 KFM66882.1 - 1.5e-06 28.4 2.0 0.026 14.6 0.0 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF1115) Myosin_head PF00063.21 KFM66883.1 - 5.8e-239 794.8 8.3 7.3e-239 794.5 8.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFM66883.1 - 1.3e-44 152.2 0.0 2.2e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding NHL PF01436.21 KFM66884.1 - 1.7e-55 182.4 19.4 2.1e-10 40.1 0.1 6.5 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 KFM66884.1 - 3e-18 66.1 5.4 5.8e-05 22.4 0.3 4.4 1 1 2 4 4 4 4 6-bladed beta-propeller SGL PF08450.12 KFM66884.1 - 7.4e-09 35.5 0.6 0.0051 16.4 0.0 4.1 3 1 2 5 5 5 4 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 KFM66884.1 - 2.1e-08 34.5 0.5 0.014 15.4 0.0 4.4 4 0 0 4 4 4 1 Esterase-like activity of phytase zf-RING_UBOX PF13445.6 KFM66884.1 - 2.4e-08 33.9 6.6 7.5e-08 32.3 6.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM66884.1 - 3.6e-07 29.9 8.4 3.6e-07 29.9 8.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM66884.1 - 1.7e-06 27.7 8.7 1.7e-06 27.7 8.7 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM66884.1 - 1.7e-05 24.6 8.2 1.7e-05 24.6 8.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM66884.1 - 2.6e-05 24.1 8.2 2.6e-05 24.1 8.2 2.5 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM66884.1 - 8.7e-05 22.6 8.0 8.7e-05 22.6 8.0 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFM66884.1 - 0.00028 21.2 8.0 0.00028 21.2 8.0 2.4 2 0 0 2 2 2 1 Ring finger domain TolB_like PF15869.5 KFM66884.1 - 0.00053 19.3 0.0 0.0085 15.4 0.0 2.3 1 1 0 2 2 2 1 TolB-like 6-blade propeller-like zf-RING_6 PF14835.6 KFM66884.1 - 0.0046 16.8 2.6 0.0046 16.8 2.6 1.8 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Nup88 PF10168.9 KFM66884.1 - 0.005 14.7 4.3 0.0079 14.1 4.3 1.2 1 0 0 1 1 1 1 Nuclear pore component SBBP PF06739.11 KFM66884.1 - 0.012 15.5 0.1 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Beta-propeller repeat FapA PF03961.13 KFM66884.1 - 0.096 11.3 3.7 0.16 10.5 3.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A COG2 PF06148.11 KFM66884.1 - 0.14 12.2 4.0 0.32 11.1 4.0 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-RING_11 PF17123.5 KFM66884.1 - 7.5 6.4 7.6 0.7 9.7 1.9 2.2 2 0 0 2 2 2 0 RING-like zinc finger ABC_tran PF00005.27 KFM66885.1 - 5.3e-36 124.1 0.0 7.7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM66885.1 - 9e-07 28.5 0.2 0.00049 19.6 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFM66885.1 - 1.1e-06 29.1 0.0 2.2e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 KFM66885.1 - 1.4e-06 27.5 0.0 0.00017 20.5 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 KFM66885.1 - 0.00012 22.3 0.4 0.0016 18.8 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM66885.1 - 0.00025 20.8 0.0 0.0018 18.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFM66885.1 - 0.0005 20.0 0.0 0.00089 19.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KFM66885.1 - 0.00092 19.1 0.0 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KFM66885.1 - 0.00096 19.6 0.0 0.91 9.9 0.0 2.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM66885.1 - 0.0013 18.7 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KFM66885.1 - 0.0027 17.9 0.7 0.046 13.9 0.7 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KFM66885.1 - 0.0028 17.3 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 KFM66885.1 - 0.0087 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain G-alpha PF00503.20 KFM66885.1 - 0.0093 15.2 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_15 PF13175.6 KFM66885.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KFM66885.1 - 0.016 14.9 0.2 0.36 10.6 0.0 2.5 3 0 0 3 3 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KFM66885.1 - 0.033 13.5 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KFM66885.1 - 0.045 13.7 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KFM66885.1 - 0.057 12.9 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KFM66885.1 - 0.061 12.5 0.1 0.1 11.8 0.1 1.5 1 1 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 KFM66885.1 - 0.064 12.8 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFM66885.1 - 0.1 12.6 0.0 0.41 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFM66885.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFM66885.1 - 0.13 11.7 0.0 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFM66885.1 - 0.17 12.3 0.1 0.77 10.2 0.0 1.9 1 1 1 2 2 2 0 RNA helicase AAA_24 PF13479.6 KFM66885.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain HTH_Tnp_Tc3_2 PF01498.18 KFM66886.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66886.1 - 3.9e-12 46.2 0.0 6.7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66886.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66886.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66886.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain I-set PF07679.16 KFM66888.1 - 2e-33 114.3 0.0 1.4e-15 57.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM66888.1 - 3.8e-32 110.7 0.0 5.3e-15 55.8 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM66888.1 - 3.3e-17 62.6 0.0 1.4e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM66888.1 - 3.3e-16 59.2 0.0 2.2e-06 27.8 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM66888.1 - 1.3e-08 34.9 0.2 0.086 13.0 0.0 4.1 2 2 2 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM66888.1 - 4.4e-05 23.5 0.3 0.011 15.8 0.0 2.7 2 1 1 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM66888.1 - 0.0007 19.9 0.0 0.41 11.1 0.0 2.3 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFM66888.1 - 0.011 15.7 0.0 3.6 7.7 0.0 2.6 2 2 0 2 2 2 0 C17orf99 Ig domain Ig_6 PF18452.1 KFM66888.1 - 0.068 12.7 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain Ig_4 PF16680.5 KFM66888.1 - 0.087 13.1 0.1 1.3 9.3 0.0 2.5 2 2 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFM66888.1 - 0.094 13.1 0.3 2.4 8.6 0.0 2.7 2 2 0 2 2 2 0 Immunoglobulin C1-set domain Y_phosphatase PF00102.27 KFM66889.1 - 5.6e-168 556.3 2.0 2.2e-84 282.7 0.3 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFM66889.1 - 2e-134 438.3 50.1 5.6e-18 65.1 0.8 9.8 9 0 0 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM66889.1 - 1.7e-18 66.9 38.8 0.0022 18.5 0.1 10.1 10 0 0 10 10 10 6 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM66889.1 - 3.5e-13 49.7 4.9 0.29 11.5 0.0 8.9 9 0 0 9 9 8 3 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 KFM66889.1 - 5.6e-09 35.9 0.0 0.00096 19.0 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain fn3_2 PF16893.5 KFM66889.1 - 2e-08 34.3 0.3 0.13 12.4 0.0 5.7 5 0 0 5 5 5 2 Fibronectin type III domain Y_phosphatase3 PF13350.6 KFM66889.1 - 6e-06 26.4 0.0 0.074 13.0 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family I-set PF07679.16 KFM66889.1 - 5.8e-05 23.1 0.0 0.00042 20.3 0.0 2.6 2 0 0 2 2 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM66889.1 - 8.8e-05 23.0 0.1 0.0027 18.3 0.0 3.7 3 0 0 3 3 3 1 Immunoglobulin domain PTPlike_phytase PF14566.6 KFM66889.1 - 8.9e-05 22.7 0.0 0.011 15.9 0.0 2.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF2369 PF10179.9 KFM66889.1 - 0.00011 22.5 0.2 7.4 7.0 0.0 5.4 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2369) Ig_2 PF13895.6 KFM66889.1 - 0.0009 19.5 0.1 0.015 15.6 0.0 3.0 2 0 0 2 2 2 1 Immunoglobulin domain Insulin_TMD PF17870.1 KFM66889.1 - 0.04 14.0 0.8 0.097 12.8 0.8 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TMEM154 PF15102.6 KFM66889.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Tissue_fac PF01108.17 KFM66889.1 - 0.079 12.8 21.8 0.31 10.9 0.1 6.3 7 1 1 8 8 8 0 Tissue factor COX2_TM PF02790.15 KFM66889.1 - 0.14 12.3 0.5 0.4 10.9 0.5 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain Tmemb_55A PF09788.9 KFM66891.1 - 3.6e-98 327.6 10.7 4.1e-98 327.4 10.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A zf-BED PF02892.15 KFM66891.1 - 0.38 10.8 0.2 0.38 10.8 0.2 3.8 2 2 2 4 4 4 0 BED zinc finger DUF1451 PF07295.11 KFM66891.1 - 9.9 6.2 12.1 9.2 6.3 3.8 2.2 2 0 0 2 2 2 0 Zinc-ribbon containing domain AMP-binding PF00501.28 KFM66893.1 - 2e-45 155.2 0.0 2.8e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM66893.1 - 7.1e-08 32.3 6.4 1.5e-07 31.3 6.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Orn_Arg_deC_N PF02784.16 KFM66894.1 - 4.1e-70 235.9 0.0 5.5e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFM66894.1 - 3.7e-15 55.9 0.0 5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-CCCH_2 PF14608.6 KFM66896.1 - 1.8e-14 53.6 58.6 0.00024 21.4 7.9 5.5 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger PWI PF01480.17 KFM66896.1 - 1.4e-07 31.7 0.9 6.6e-07 29.5 0.2 2.2 2 0 0 2 2 2 1 PWI domain zf_CCCH_4 PF18345.1 KFM66896.1 - 0.066 13.3 0.8 0.066 13.3 0.8 6.6 9 0 0 9 9 9 0 Zinc finger domain Nab2 PF11517.8 KFM66896.1 - 0.077 13.3 0.4 0.2 12.0 0.1 1.8 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH PF00642.24 KFM66896.1 - 0.16 12.0 0.3 0.16 12.0 0.3 5.6 5 4 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GalP_UDP_transf PF01087.22 KFM66897.1 - 3.1e-65 220.0 0.0 4.8e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KFM66897.1 - 1.1e-60 204.2 1.2 1.3e-60 204.0 0.3 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4931 PF16285.5 KFM66897.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) GalP_UDP_transf PF01087.22 KFM66899.1 - 6.2e-61 206.0 0.0 8.7e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KFM66899.1 - 8.8e-55 185.0 0.4 1.5e-54 184.2 0.4 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4931 PF16285.5 KFM66899.1 - 0.098 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) FERM_C PF09380.10 KFM66900.1 - 9.5e-06 25.9 0.3 2.4e-05 24.6 0.3 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFM66901.1 - 1.9e-09 38.0 0.0 3.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFM66901.1 - 7.5e-05 22.6 0.1 0.00021 21.2 0.0 1.8 2 0 0 2 2 2 1 FERM N-terminal domain TrmE_N PF10396.9 KFM66902.1 - 1.2e-05 25.7 0.8 2.6e-05 24.5 0.6 1.6 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KFM66903.1 - 6.8e-31 108.0 0.4 8.2e-31 107.8 0.4 1.1 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KFM66903.1 - 6.9e-23 80.9 0.2 1.7e-22 79.7 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM66903.1 - 7.9e-10 38.5 0.1 3.8e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM66903.1 - 2.7e-09 37.2 0.2 0.00078 19.4 0.2 2.5 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KFM66903.1 - 1.1e-06 28.8 0.7 1.4e-05 25.2 0.2 2.5 2 1 1 3 3 3 1 Dynamin family Ras PF00071.22 KFM66903.1 - 7.5e-06 25.6 0.0 7.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Ras family MMR_HSR1_Xtn PF16897.5 KFM66903.1 - 0.00013 21.9 0.2 0.0005 20.1 0.0 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain Roc PF08477.13 KFM66903.1 - 0.00014 22.0 0.1 0.0012 19.0 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KFM66903.1 - 0.00017 21.0 0.5 0.00057 19.3 0.2 1.9 2 0 0 2 2 2 1 AIG1 family Gtr1_RagA PF04670.12 KFM66903.1 - 0.00068 19.0 0.1 0.0014 18.0 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MCM PF00493.23 KFM66903.1 - 0.0039 16.3 0.1 0.0062 15.6 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain cobW PF02492.19 KFM66903.1 - 0.024 14.2 0.3 0.84 9.2 0.3 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KFM66903.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFM66903.1 - 0.038 14.3 0.1 3.5 7.9 0.1 2.9 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM66903.1 - 0.055 14.0 0.0 0.094 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KFM66903.1 - 0.062 12.8 0.0 4.4 6.8 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFM66903.1 - 0.096 13.1 0.1 0.2 12.1 0.1 1.8 1 1 1 2 2 2 0 AAA ATPase domain PI31_Prot_N PF11566.8 KFM66904.1 - 2.8e-19 69.5 0.4 4e-19 69.0 0.4 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KFM66904.1 - 0.00012 23.2 9.3 0.00022 22.3 8.9 1.8 1 1 0 1 1 1 1 PI31 proteasome regulator DUF3747 PF12565.8 KFM66904.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) DUF659 PF04937.15 KFM66905.1 - 0.008 16.0 0.9 0.011 15.6 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Sortilin-Vps10 PF15902.5 KFM66906.1 - 9.9e-105 350.9 0.5 1.6e-104 350.2 0.5 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Ldl_recept_a PF00057.18 KFM66906.1 - 1.7e-89 293.7 171.7 1.3e-11 44.5 11.2 9.9 10 0 0 10 10 10 9 Low-density lipoprotein receptor domain class A Sortilin_C PF15901.5 KFM66906.1 - 2.6e-40 138.6 5.0 2.6e-40 138.6 5.0 5.1 2 1 3 6 6 6 1 Sortilin, neurotensin receptor 3, C-terminal Ldl_recept_b PF00058.17 KFM66906.1 - 3.2e-26 91.5 2.5 1.1e-07 32.2 0.0 5.3 5 0 0 5 5 5 4 Low-density lipoprotein receptor repeat class B fn3 PF00041.21 KFM66906.1 - 1e-23 83.5 15.6 1.3e-07 31.8 0.1 6.2 6 0 0 6 6 6 5 Fibronectin type III domain BNR PF02012.20 KFM66906.1 - 0.00041 19.9 13.3 1.5 9.1 0.8 6.2 5 0 0 5 5 5 2 BNR/Asp-box repeat DUF5050 PF16472.5 KFM66906.1 - 0.00058 19.2 0.4 0.0021 17.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5050) BNR_6 PF15899.5 KFM66906.1 - 0.015 15.3 13.4 0.15 12.2 0.2 5.2 5 0 0 5 5 5 0 BNR-Asp box repeat Interfer-bind PF09294.10 KFM66906.1 - 0.066 13.5 0.3 0.92 9.9 0.0 2.9 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KFM66906.1 - 0.64 10.6 8.9 2.9 8.5 0.0 4.6 5 0 0 5 5 5 0 Purple acid Phosphatase, N-terminal domain DDE_3 PF13358.6 KFM66907.1 - 0.0046 16.7 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4817 PF16087.5 KFM66908.1 - 7.2e-07 28.9 0.8 2.4e-06 27.3 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) DDE_3 PF13358.6 KFM66908.1 - 0.00029 20.6 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SAM_PNT PF02198.16 KFM66909.1 - 5.5e-26 90.4 0.1 7.5e-26 89.9 0.1 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain zf-C2H2_6 PF13912.6 KFM66910.1 - 0.00027 20.8 0.9 0.00059 19.8 0.9 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger SAGA-Tad1 PF12767.7 KFM66910.1 - 0.00039 20.2 2.5 0.00039 20.2 2.5 1.9 1 1 1 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit zf-C2H2_jaz PF12171.8 KFM66910.1 - 0.0015 18.7 0.3 0.0015 18.7 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM66910.1 - 0.016 15.6 0.3 0.016 15.6 0.3 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 KFM66910.1 - 0.035 13.7 0.1 0.098 12.3 0.1 1.7 1 0 0 1 1 1 0 MYST family zinc finger domain zf-C2H2 PF00096.26 KFM66910.1 - 0.045 14.2 0.3 0.13 12.8 0.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM66910.1 - 0.05 14.5 0.5 0.05 14.5 0.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1933 PF09147.10 KFM66910.1 - 0.069 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) Rpp20 PF12328.8 KFM66911.1 - 1.5e-12 47.7 2.0 2e-10 40.7 0.2 2.4 2 1 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KFM66911.1 - 4e-12 45.8 0.6 6.2e-12 45.2 0.2 1.5 2 0 0 2 2 2 1 Alba IQ PF00612.27 KFM66914.1 - 0.078 12.8 1.7 0.14 12.0 0.1 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif NUC130_3NT PF08158.12 KFM66915.1 - 0.01 16.2 0.5 0.026 14.8 0.3 1.9 1 1 1 2 2 2 0 NUC130/3NT domain IclR PF01614.18 KFM66915.1 - 0.047 13.5 1.1 0.1 12.5 1.1 1.5 1 0 0 1 1 1 0 Bacterial transcriptional regulator Exonuc_VII_L PF02601.15 KFM66915.1 - 0.24 10.9 3.4 0.28 10.7 3.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NBD_C PF17042.5 KFM66915.1 - 0.58 10.6 1.8 0.92 10.0 1.8 1.3 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain DUF4763 PF15960.5 KFM66915.1 - 7.6 5.8 18.8 0.43 9.8 12.5 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4763) GRAM PF02893.20 KFM66917.1 - 9.1e-09 35.2 0.0 1e-08 35.1 0.0 1.0 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KFM66917.1 - 8e-05 22.7 0.0 0.0001 22.4 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 HNH_4 PF13395.6 KFM66917.1 - 0.064 13.2 0.1 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 HNH endonuclease RRN3 PF05327.11 KFM66919.1 - 0.06 11.9 0.1 0.06 11.9 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Glyco_transf_17 PF04724.13 KFM66920.1 - 0.026 13.6 1.1 0.055 12.5 0.2 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 17 NYD-SP12_N PF15015.6 KFM66920.1 - 0.17 10.2 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Glyco_transf_17 PF04724.13 KFM66921.1 - 0.0024 17.0 0.6 0.024 13.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 17 DUF4489 PF14879.6 KFM66921.1 - 0.039 14.1 0.9 0.061 13.4 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) HTH_Tnp_Tc3_2 PF01498.18 KFM66922.1 - 3.7e-16 59.1 3.4 5.3e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66922.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66922.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66922.1 - 0.0025 17.6 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66922.1 - 2.1 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Integrase_H2C2 PF17921.1 KFM66923.1 - 2.3e-07 30.8 0.6 4.5e-07 29.9 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM66923.1 - 5.9e-05 23.2 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain BTB PF00651.31 KFM66924.1 - 7.7e-23 80.8 2.4 1.5e-22 79.9 2.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM66924.1 - 0.034 14.2 0.6 0.33 11.1 0.0 2.6 3 0 0 3 3 3 0 BTB And C-terminal Kelch GluRS_N PF18466.1 KFM66924.1 - 0.04 14.3 0.3 0.07 13.5 0.3 1.4 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain BTB PF00651.31 KFM66925.1 - 8.8e-18 64.6 0.8 1.3e-17 64.0 0.8 1.3 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KFM66926.1 - 1.5e-16 60.3 11.4 2.7e-12 46.3 8.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_U4 PF03419.13 KFM66926.1 - 7.9 5.7 10.9 0.49 9.6 5.3 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA HTH_Tnp_Tc3_2 PF01498.18 KFM66927.1 - 2e-09 37.6 0.9 3.2e-09 36.9 0.9 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66927.1 - 0.01 15.6 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_32 PF13565.6 KFM66927.1 - 1.1 9.9 8.0 9.6 6.9 3.0 3.3 2 1 2 4 4 4 0 Homeodomain-like domain RCC1 PF00415.18 KFM66928.1 - 5.4e-80 263.9 8.9 1.7e-13 50.9 0.9 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM66928.1 - 1.6e-29 101.1 34.0 6.9e-08 32.1 0.4 8.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KFM66928.1 - 0.23 11.9 2.4 1.8 9.0 0.0 3.3 4 1 1 5 5 5 0 SUKH-3 immunity protein HTH_48 PF17906.1 KFM66929.1 - 5.8e-15 55.2 0.3 9e-15 54.5 0.3 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_50 PF18024.1 KFM66929.1 - 2.5e-05 23.8 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 KFM66929.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 HTH domain HTH_32 PF13565.6 KFM66929.1 - 0.14 12.7 0.0 0.28 11.8 0.0 1.4 1 1 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KFM66929.1 - 0.16 12.1 0.0 3.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain IF-2B PF01008.17 KFM66930.1 - 4.1e-64 216.5 0.4 5.5e-64 216.1 0.4 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family EcoEI_R_C PF08463.10 KFM66930.1 - 0.0011 19.1 0.7 0.0098 16.0 0.6 2.2 1 1 1 2 2 2 1 EcoEI R protein C-terminal Med7 PF05983.11 KFM66930.1 - 0.015 15.4 0.5 0.041 14.0 0.2 1.6 1 1 0 1 1 1 0 MED7 protein FliM PF02154.15 KFM66930.1 - 0.045 13.6 0.6 4.7 7.0 0.2 2.4 1 1 1 2 2 2 0 Flagellar motor switch protein FliM RB_A PF01858.17 KFM66930.1 - 0.073 12.9 2.3 0.24 11.2 0.5 2.1 1 1 1 2 2 2 0 Retinoblastoma-associated protein A domain DUF676 PF05057.14 KFM66930.1 - 0.075 12.5 0.3 5 6.6 0.0 2.4 1 1 1 2 2 2 0 Putative serine esterase (DUF676) MADF_DNA_bdg PF10545.9 KFM66930.1 - 0.11 12.8 0.3 0.4 11.0 0.1 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_3 PF13358.6 KFM66931.1 - 0.05 13.4 0.1 0.07 12.9 0.0 1.3 1 1 0 1 1 1 0 DDE superfamily endonuclease UQ_con PF00179.26 KFM66932.1 - 9.6e-45 151.7 0.1 1.3e-44 151.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM66932.1 - 0.0012 18.6 0.1 0.0056 16.4 0.0 2.1 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 KFM66932.1 - 0.0055 17.0 0.1 0.0094 16.2 0.1 1.6 1 0 0 1 1 1 1 RWD domain PROCN PF08083.11 KFM66933.1 - 3e-234 777.1 7.8 3e-234 777.1 7.8 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KFM66933.1 - 1e-129 431.0 0.8 1.7e-129 430.3 0.8 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KFM66933.1 - 4.8e-90 299.6 2.7 1.1e-89 298.5 2.7 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KFM66933.1 - 2e-87 290.8 5.3 2e-87 290.8 5.3 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KFM66933.1 - 1.5e-74 248.4 0.1 8.1e-74 246.1 0.0 2.2 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KFM66933.1 - 1.8e-52 176.5 0.0 4.8e-52 175.1 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KFM66933.1 - 6.5e-48 161.0 0.6 1.8e-47 159.6 0.6 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 KFM66933.1 - 3.1e-10 40.1 0.0 1.1e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease 7TM_GPCR_Srw PF10324.9 KFM66935.1 - 2.9e-37 128.6 18.0 4.5e-37 128.0 18.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KFM66935.1 - 3.5e-18 65.9 14.9 4.6e-18 65.5 14.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM66935.1 - 1.2e-08 34.9 14.0 1.2e-08 34.9 14.0 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx HTH_Tnp_Tc3_2 PF01498.18 KFM66936.1 - 4.2e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66936.1 - 1.1e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66936.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66936.1 - 0.0023 17.7 0.6 0.007 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66936.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66937.1 - 4.7e-16 58.8 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66937.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66937.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66937.1 - 0.0027 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66937.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain 7TM_GPCR_Srw PF10324.9 KFM66938.1 - 5.2e-07 29.3 0.0 5.5e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw eIF-5_eIF-2B PF01873.17 KFM66939.1 - 1.1e-40 138.2 0.2 1.9e-40 137.4 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 SLX9 PF15341.6 KFM66939.1 - 1.7 9.0 10.4 0.26 11.7 5.0 2.1 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 TFIIA PF03153.13 KFM66942.1 - 0.021 14.9 12.6 0.022 14.8 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HTH_Tnp_Tc3_2 PF01498.18 KFM66944.1 - 2.6e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66944.1 - 1e-13 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66945.1 - 2.3e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66945.1 - 9.7e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_48 PF17906.1 KFM66946.1 - 1.6e-06 28.1 0.6 2.8e-06 27.3 0.6 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM66946.1 - 0.00012 22.6 2.7 0.00047 20.7 0.0 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 KFM66946.1 - 0.026 14.1 0.1 0.048 13.2 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM66946.1 - 0.027 14.3 1.5 6.5 6.7 0.2 3.3 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66946.1 - 0.041 14.1 0.4 0.11 12.8 0.4 1.7 1 1 0 1 1 1 0 Transposase SpoIIID PF12116.8 KFM66946.1 - 0.043 13.9 0.2 0.072 13.2 0.2 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D Pep_M12B_propep PF01562.19 KFM66948.1 - 2e-16 60.5 0.4 2.3e-16 60.3 0.4 1.0 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KFM66949.1 - 5.5e-19 68.9 0.7 5.9e-19 68.8 0.7 1.0 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KFM66949.1 - 4.9e-08 33.4 1.8 6.2e-08 33.0 1.8 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFM66949.1 - 1.8e-05 24.7 2.3 3.6e-05 23.8 2.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFM66949.1 - 3.9e-05 23.4 0.3 6e-05 22.8 0.3 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KFM66949.1 - 0.0003 20.8 1.4 0.00041 20.4 1.4 1.3 1 1 0 1 1 1 1 Peptidase family M54 Reprolysin_3 PF13582.6 KFM66949.1 - 0.0014 19.1 3.5 0.0023 18.4 3.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Zincin_1 PF06262.11 KFM66949.1 - 0.0023 18.0 0.9 0.003 17.6 0.9 1.2 1 0 0 1 1 1 1 Zincin-like metallopeptidase Peptidase_M66 PF10462.9 KFM66949.1 - 0.0048 15.9 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 KFM66949.1 - 0.056 13.3 0.3 0.067 13.0 0.3 1.3 1 1 0 1 1 1 0 Matrixin ROK PF00480.20 KFM66949.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.0 1 0 0 1 1 1 0 ROK family ADAM_CR PF08516.12 KFM66950.1 - 7.1e-14 52.2 0.4 7.1e-14 52.2 0.4 2.0 2 0 0 2 2 2 1 ADAM cysteine-rich ADAM_CR_2 PF17771.1 KFM66950.1 - 0.0003 21.2 7.1 0.0054 17.2 0.7 2.3 1 1 1 2 2 2 2 ADAM cysteine-rich domain DUF1981 PF09324.10 KFM66953.1 - 8.9e-35 118.4 0.2 8.9e-35 118.4 0.2 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) ANAPC4_WD40 PF12894.7 KFM66953.1 - 0.087 13.1 0.0 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DCB PF16213.5 KFM66954.1 - 1.2e-35 122.8 1.0 2.4e-35 121.8 1.0 1.5 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KFM66954.1 - 8.6e-14 51.7 3.3 1.5e-13 50.9 0.1 2.7 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DRIM PF07539.12 KFM66954.1 - 0.024 13.0 0.1 0.034 12.5 0.1 1.4 1 0 0 1 1 1 0 Down-regulated in metastasis HK97-gp10_like PF04883.12 KFM66954.1 - 0.15 13.0 0.9 1.1 10.3 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Hemocyanin_M PF00372.19 KFM66955.1 - 6.5e-72 242.0 0.6 1e-71 241.3 0.6 1.3 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Hemocyanin_C PF03723.14 KFM66955.1 - 1.7e-70 237.2 0.0 2.4e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_N PF03722.14 KFM66955.1 - 2.5e-18 66.8 0.1 8.9e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Hemocyanin, all-alpha domain Tyrosinase PF00264.20 KFM66955.1 - 8.6e-09 36.0 0.3 1.7e-08 35.1 0.1 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Hemocyanin_M PF00372.19 KFM66956.1 - 7.5e-71 238.5 0.2 1.1e-70 238.0 0.2 1.2 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Hemocyanin_C PF03723.14 KFM66956.1 - 1e-68 231.4 0.0 1.4e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_N PF03722.14 KFM66956.1 - 1.3e-19 70.9 0.0 4.3e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 Hemocyanin, all-alpha domain Tyrosinase PF00264.20 KFM66956.1 - 3.9e-09 37.1 0.3 6.3e-09 36.4 0.3 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase AhpC-TSA PF00578.21 KFM66957.1 - 3.7e-40 136.7 0.0 5.1e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM66957.1 - 4.5e-16 58.9 0.0 5.8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFM66957.1 - 3.5e-10 39.5 0.5 7.4e-10 38.5 0.2 1.8 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin Trigger_C PF05698.14 KFM66958.1 - 0.0053 16.8 0.8 0.01 15.9 0.5 1.6 1 1 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus DUF1690 PF07956.11 KFM66958.1 - 0.018 15.4 1.5 0.27 11.6 1.5 2.0 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) VASP_tetra PF08776.11 KFM66958.1 - 0.041 13.4 3.8 0.51 10.0 0.6 3.1 3 0 0 3 3 3 0 VASP tetramerisation domain CelTOS PF18659.1 KFM66958.1 - 0.1 13.1 0.1 0.86 10.0 0.0 2.0 1 1 1 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites GlutR_dimer PF00745.20 KFM66958.1 - 0.15 12.5 1.7 0.94 10.0 0.1 2.4 1 1 2 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Ribosomal_L29 PF00831.23 KFM66958.1 - 0.24 11.4 3.5 0.2 11.7 0.6 2.2 2 1 0 2 2 2 0 Ribosomal L29 protein Ion_trans PF00520.31 KFM66959.1 - 0.00047 19.5 0.5 0.00064 19.0 0.5 1.2 1 0 0 1 1 1 1 Ion transport protein HTH_Tnp_Tc3_2 PF01498.18 KFM66960.1 - 4.9e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66960.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66960.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66960.1 - 0.0027 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66960.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM66961.1 - 1.8e-16 60.1 2.2 5.2e-16 58.7 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM66961.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66961.1 - 2.9e-07 30.1 1.7 7.7e-07 28.8 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66961.1 - 0.0035 17.1 0.8 0.01 15.6 0.8 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66961.1 - 2.6 8.7 16.2 0.1 13.2 1.8 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ank_2 PF12796.7 KFM66962.1 - 4.6e-14 52.8 0.9 7.9e-08 32.8 0.1 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) TRP_2 PF08344.11 KFM66962.1 - 1.7e-13 50.5 1.0 2.8e-13 49.9 1.0 1.3 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_3 PF13606.6 KFM66962.1 - 5.1e-10 38.7 0.1 0.19 12.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFM66962.1 - 2e-08 34.6 0.7 0.0011 19.5 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM66962.1 - 2.8e-05 24.4 0.1 2.7 8.6 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFM66962.1 - 4.1e-05 23.8 0.2 0.57 10.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) HTH_Tnp_Tc3_2 PF01498.18 KFM66964.1 - 3.2e-16 59.3 3.0 6.3e-16 58.4 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66964.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66964.1 - 1.9e-08 33.9 3.6 7.6e-07 28.8 0.2 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_48 PF17906.1 KFM66964.1 - 2.1e-07 30.9 0.1 4.2e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_23 PF13384.6 KFM66964.1 - 0.0031 17.2 1.7 0.0082 15.9 0.6 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM66964.1 - 0.028 14.5 2.2 0.098 12.8 0.4 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Peptidase_M8 PF01457.16 KFM66965.1 - 4.6e-27 94.9 9.8 7e-27 94.3 1.0 2.2 1 1 1 2 2 2 2 Leishmanolysin fn3 PF00041.21 KFM66966.1 - 5.8e-150 488.1 62.5 1.6e-19 70.0 1.7 12.8 13 0 0 13 13 13 12 Fibronectin type III domain Y_phosphatase PF00102.27 KFM66966.1 - 1.5e-77 260.4 0.1 4.8e-77 258.7 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Pur_ac_phosph_N PF16656.5 KFM66966.1 - 2.6e-33 114.5 42.8 0.0056 17.2 0.5 11.4 10 0 0 10 10 10 10 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM66966.1 - 5.8e-22 78.0 14.2 0.037 14.3 0.1 10.5 10 0 0 10 10 10 7 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 KFM66966.1 - 3.8e-17 62.2 14.0 0.038 14.1 0.2 9.8 10 0 0 10 10 10 6 Fibronectin type III domain PTP_tm PF18861.1 KFM66966.1 - 3.2e-06 27.3 4.3 5.6 6.9 0.0 7.4 8 0 0 8 8 8 2 Transmembrane domain of protein tyrosine phosphatase, receptor type J DSPc PF00782.20 KFM66966.1 - 0.00085 19.1 0.0 0.0026 17.6 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM66966.1 - 0.0032 17.5 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family SusE PF14292.6 KFM66966.1 - 0.0036 17.5 12.7 2.7 8.3 0.1 6.6 8 1 1 9 9 8 2 SusE outer membrane protein ArsR PF09824.9 KFM66966.1 - 0.0061 16.2 8.5 1.1 8.9 0.2 5.2 4 1 1 5 5 5 1 ArsR transcriptional regulator PTPlike_phytase PF14566.6 KFM66966.1 - 0.012 15.8 0.0 0.04 14.0 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF4968 PF16338.5 KFM66966.1 - 0.054 13.8 4.1 35 4.8 0.1 5.4 6 0 0 6 6 5 0 Domain of unknown function (DUF4968) DUF4945 PF16303.5 KFM66966.1 - 1.6 8.7 3.7 9.1 6.2 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4945) 2OG-FeII_Oxy_2 PF13532.6 KFM66967.1 - 8.3e-26 91.4 0.0 1.6e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAM2 PF07145.15 KFM66967.1 - 0.053 13.2 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region KH_8 PF17903.1 KFM66968.1 - 5.3e-29 100.1 0.0 5.3e-29 100.1 0.0 2.2 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 KFM66968.1 - 0.038 13.8 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 KH domain PIEZO PF15917.5 KFM66968.1 - 0.99 8.8 6.1 1.5 8.3 6.1 1.2 1 0 0 1 1 1 0 Piezo RIO1 PF01163.22 KFM66969.1 - 4.6e-72 241.6 0.1 4.6e-72 241.6 0.1 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KFM66969.1 - 0.00068 18.5 0.1 0.00068 18.5 0.1 2.5 2 1 0 2 2 2 1 Fungal protein kinase Phage_connect_1 PF05135.13 KFM66969.1 - 0.046 14.2 0.9 0.14 12.6 0.9 1.8 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein BSP_II PF05432.11 KFM66969.1 - 7.1 6.2 21.3 0.16 11.6 12.3 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) HMG_box PF00505.19 KFM66970.1 - 1.2e-24 86.4 2.2 1.2e-24 86.4 2.2 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM66970.1 - 2.2e-08 34.5 0.8 2.2e-08 34.5 0.8 2.7 4 0 0 4 4 4 1 HMG-box domain DUF4642 PF15484.6 KFM66970.1 - 0.0072 16.6 8.7 0.014 15.6 6.9 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4642) Allexi_40kDa PF05549.11 KFM66970.1 - 1.3 8.4 4.7 3.1 7.2 4.7 1.6 1 0 0 1 1 1 0 Allexivirus 40kDa protein Pro_CA PF00484.19 KFM66970.1 - 2.8 8.2 5.1 5.7 7.2 5.1 1.4 1 0 0 1 1 1 0 Carbonic anhydrase DUF2203 PF09969.9 KFM66970.1 - 5.3 7.8 7.4 13 6.5 7.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Exo_endo_phos_2 PF14529.6 KFM66973.1 - 2.9e-19 69.1 3.0 3.2e-19 68.9 3.0 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM66973.1 - 0.0077 15.8 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LicD PF04991.13 KFM66976.1 - 0.081 13.1 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 LicD family HTH_Tnp_Tc3_2 PF01498.18 KFM66977.1 - 1.2e-17 63.8 1.5 4.8e-16 58.8 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66977.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4078 PF13300.6 KFM66978.1 - 2.1e-24 85.7 7.9 2.1e-24 85.7 7.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) PRT_C PF08372.10 KFM66978.1 - 0.35 10.6 1.1 0.38 10.5 0.1 1.5 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal LSM PF01423.22 KFM66979.1 - 1.1e-21 76.2 0.8 1.3e-21 76.0 0.8 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KFM66979.1 - 0.041 14.0 0.2 0.062 13.4 0.2 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain SM-ATX PF14438.6 KFM66979.1 - 0.047 13.8 0.0 0.061 13.5 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain PGK PF00162.19 KFM66980.1 - 2.3e-149 497.5 1.4 2.6e-149 497.3 1.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Cupin_3 PF05899.12 KFM66980.1 - 0.17 11.6 4.0 0.17 11.6 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Pkinase PF00069.25 KFM66981.1 - 8.8e-69 231.8 0.0 1e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM66981.1 - 5.3e-33 114.4 0.0 7.8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM66981.1 - 4.2e-08 32.5 0.0 6.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM66981.1 - 9.4e-05 21.9 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFM66981.1 - 0.0012 18.9 0.1 0.026 14.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM66981.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NOG1_N PF17835.1 KFM66982.1 - 1.2e-52 178.1 1.9 1.2e-52 178.1 1.9 2.1 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KFM66982.1 - 3.8e-25 87.4 0.2 9.1e-25 86.2 0.2 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 KFM66982.1 - 1.5e-20 72.9 3.1 3.2e-20 71.9 3.1 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 KFM66982.1 - 3.8e-19 68.9 0.0 9.3e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM66982.1 - 4e-11 42.7 0.0 7.1e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KFM66982.1 - 7e-06 25.6 0.0 1.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFM66982.1 - 7.7e-05 22.7 0.8 0.05 13.5 0.0 3.2 3 1 0 3 3 3 2 RsgA GTPase AIG1 PF04548.16 KFM66982.1 - 0.0024 17.2 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 KFM66982.1 - 0.013 15.7 0.0 0.096 12.9 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KFM66982.1 - 0.015 15.4 5.5 0.61 10.1 0.0 3.4 2 2 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 KFM66982.1 - 0.028 14.8 0.0 0.082 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 KFM66982.1 - 0.044 13.1 7.2 0.37 10.0 1.0 2.9 2 1 1 3 3 3 0 Septin RVT_1 PF00078.27 KFM66983.1 - 2.6e-45 154.6 0.2 4e-45 154.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFR_dimer PF04253.15 KFM66983.1 - 0.074 13.2 2.7 2.2 8.4 0.9 2.3 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain DDE_3 PF13358.6 KFM66984.1 - 3.9e-16 59.1 0.1 5e-15 55.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM66984.1 - 7.1e-16 58.2 6.5 1.3e-15 57.4 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM66984.1 - 0.00065 20.3 1.5 0.00065 20.3 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM66984.1 - 0.02 14.7 0.1 1 9.2 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_29 PF13551.6 KFM66984.1 - 0.064 13.3 2.4 0.082 12.9 0.3 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDE_Tnp_4 PF13359.6 KFM66985.1 - 1.6e-32 112.3 0.0 3.3e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM66985.1 - 1.7e-11 44.1 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFM66985.1 - 9.6e-06 25.4 0.0 0.00044 20.0 0.0 2.3 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 KFM66985.1 - 0.016 14.9 0.0 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease ANAPC4_WD40 PF12894.7 KFM66986.1 - 1.8e-14 53.8 1.9 1.7e-05 25.0 0.0 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM66986.1 - 9.3e-10 39.0 5.2 0.33 11.9 0.0 4.4 3 1 1 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.11 KFM66986.1 - 0.02 14.8 0.2 0.25 11.2 0.0 2.4 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KFM66986.1 - 0.061 12.4 0.3 0.41 9.6 0.2 2.2 2 1 1 3 3 3 0 Coatomer WD associated region ANAPC4_WD40 PF12894.7 KFM66987.1 - 0.0098 16.2 0.0 0.78 10.1 0.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KFM66988.1 - 0.0003 20.7 0.8 0.0003 20.7 0.8 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM66988.1 - 0.00032 20.4 3.5 0.0012 18.6 0.8 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM66988.1 - 0.0017 18.6 2.2 0.013 15.7 0.4 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM66988.1 - 0.0071 15.6 0.3 0.015 14.6 0.2 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM66988.1 - 0.0097 15.9 3.1 0.1 12.7 1.5 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat RRM_occluded PF16842.5 KFM66988.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif ANAPC3 PF12895.7 KFM66988.1 - 0.014 15.6 1.3 0.11 12.7 1.2 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFM66988.1 - 0.025 14.4 0.7 0.088 12.7 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM66988.1 - 0.053 13.2 2.2 0.17 11.6 2.2 2.0 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.6 KFM66988.1 - 0.17 12.8 1.1 0.52 11.3 0.2 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat C2 PF00168.30 KFM66990.1 - 6e-18 65.0 0.0 8.8e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain HTH_Tnp_Tc3_2 PF01498.18 KFM66991.1 - 3.9e-16 59.1 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66991.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM66991.1 - 2.6e-07 30.3 1.6 7.6e-07 28.8 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM66991.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM66991.1 - 2.8 8.6 15.6 0.13 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain SAM_1 PF00536.30 KFM66994.1 - 3.1e-15 56.3 0.1 6.8e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM66994.1 - 1.6e-13 50.5 0.1 4.6e-13 49.1 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LOR PF04525.12 KFM66994.1 - 2.7 7.5 5.2 1.1 8.8 0.4 2.3 2 0 0 2 2 2 0 LURP-one-related SMN PF06003.12 KFM66995.1 - 5.4e-25 88.1 31.4 4.6e-18 65.4 17.0 4.1 2 1 1 3 3 3 3 Survival motor neuron protein (SMN) DUF4176 PF13780.6 KFM66995.1 - 0.021 14.9 0.1 0.042 13.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) Aldedh PF00171.22 KFM66996.1 - 4.7e-88 295.7 0.0 5.3e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Phytochelatin PF05023.14 KFM66997.1 - 0.079 12.2 0.0 0.082 12.1 0.0 1.0 1 0 0 1 1 1 0 Phytochelatin synthase HTH_48 PF17906.1 KFM66997.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain in Mos1 transposase HTH_Tnp_Tc3_2 PF01498.18 KFM66999.1 - 4.8e-14 52.4 2.3 5.2e-14 52.2 1.0 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM66999.1 - 6.6e-14 51.9 0.0 8.6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_S17e PF00833.18 KFM67001.1 - 1.4e-67 225.2 0.7 1.6e-67 225.0 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S17 LRR_9 PF14580.6 KFM67002.1 - 2.8e-31 108.4 6.9 5.8e-15 55.2 0.8 3.4 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 KFM67002.1 - 3.2e-19 68.7 33.6 3.8e-05 24.0 1.0 6.6 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM67002.1 - 2.6e-14 52.7 32.0 2e-05 24.3 11.0 4.9 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KFM67002.1 - 1.2 9.9 25.1 23 6.0 0.4 7.9 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 KFM67002.1 - 1.3 9.3 17.6 4.4 7.6 0.3 5.9 6 0 0 6 6 6 0 Leucine Rich repeat Dimer_Tnp_hAT PF05699.14 KFM67003.1 - 0.0021 17.8 0.4 0.0064 16.3 0.0 2.0 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region Thioredoxin PF00085.20 KFM67004.1 - 3.5e-63 210.0 1.6 4.6e-30 103.7 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KFM67004.1 - 3.5e-37 128.1 9.7 9e-34 117.0 8.1 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KFM67004.1 - 1.3e-08 34.8 0.7 0.0026 17.6 0.0 3.6 3 1 0 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.6 KFM67004.1 - 1.6e-08 34.7 1.0 0.035 14.4 0.0 5.0 4 2 2 6 6 6 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KFM67004.1 - 2.4e-08 34.4 2.0 0.0038 17.7 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFM67004.1 - 7.3e-08 32.5 0.0 0.0061 16.7 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 KFM67004.1 - 1.1e-06 28.4 0.1 0.44 10.3 0.0 3.5 3 0 0 3 3 3 3 Redoxin Calsequestrin PF01216.17 KFM67004.1 - 1.9e-05 23.9 1.3 2.9e-05 23.3 0.7 1.5 1 1 0 1 1 1 1 Calsequestrin TraF PF13728.6 KFM67004.1 - 0.00013 21.9 0.2 0.0084 16.0 0.0 3.1 3 0 0 3 3 3 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 KFM67004.1 - 0.00078 18.9 0.0 0.082 12.3 0.0 2.7 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 KFM67004.1 - 0.00097 19.3 0.2 0.42 10.8 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin SBP_bac_6 PF13343.6 KFM67004.1 - 0.032 13.6 0.2 0.057 12.8 0.2 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Thioredoxin_9 PF14595.6 KFM67004.1 - 0.046 13.5 0.1 3.1 7.6 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin La PF05383.17 KFM67005.1 - 5.4e-18 64.8 0.1 1.2e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 La domain SUZ-C PF12901.7 KFM67005.1 - 9.5e-05 22.3 0.1 0.00022 21.2 0.1 1.7 1 0 0 1 1 1 1 SUZ-C motif RRM_1 PF00076.22 KFM67005.1 - 0.00061 19.6 0.1 0.014 15.2 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KFM67005.1 - 0.0012 18.8 0.0 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif GCD14 PF08704.10 KFM67005.1 - 0.021 14.5 0.4 0.021 14.5 0.4 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit RRM_5 PF13893.6 KFM67005.1 - 0.035 13.7 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 KFM67005.1 - 1.4 7.2 9.3 1.9 6.6 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KFM67006.1 - 3.2e-20 72.6 0.0 3.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CK1gamma_C PF12605.8 KFM67006.1 - 7.5e-10 39.9 0.4 1.3e-09 39.1 0.4 1.4 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase_Tyr PF07714.17 KFM67006.1 - 1.6e-09 37.5 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM67006.1 - 7.4e-08 31.6 0.4 9.9e-08 31.2 0.4 1.1 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 KFM67006.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 YrbL-PhoP_reg PF10707.9 KFM67006.1 - 0.091 12.3 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Perilipin PF03036.16 KFM67008.1 - 6.3e-37 127.5 0.2 6.3e-37 127.5 0.2 1.4 2 0 0 2 2 2 1 Perilipin family MCM3AP_GANP PF16769.5 KFM67008.1 - 0.045 12.0 4.5 0.071 11.4 4.5 1.3 1 1 0 1 1 1 0 MCM3AP domain of GANP Med2 PF11214.8 KFM67008.1 - 5.3 7.3 7.2 5.3 7.3 0.3 3.0 3 0 0 3 3 3 0 Mediator complex subunit 2 DUF4770 PF15994.5 KFM67008.1 - 9.7 6.4 7.2 0.59 10.4 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4770) HTH_Tnp_Tc3_2 PF01498.18 KFM67009.1 - 5.5e-16 58.6 2.2 5.5e-16 58.6 2.2 2.2 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM67009.1 - 1.8e-11 44.0 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67009.1 - 2.4e-08 33.6 1.6 6.5e-08 32.2 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67009.1 - 0.0071 16.1 0.7 0.021 14.6 0.7 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67009.1 - 0.011 15.9 0.5 0.035 14.2 0.5 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM67009.1 - 0.37 11.4 16.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67011.1 - 3e-16 59.4 3.1 4.7e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67011.1 - 9.5e-14 51.4 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67013.1 - 2.2e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67013.1 - 9.4e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease p450 PF00067.22 KFM67014.1 - 1.7e-78 264.5 0.5 2.1e-78 264.2 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM67015.1 - 1.5e-71 241.5 0.2 1.7e-71 241.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1125 PF06563.11 KFM67015.1 - 0.046 13.6 0.5 0.35 10.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1125) Beta_helix PF13229.6 KFM67016.1 - 2.6e-07 30.6 3.6 4.7e-07 29.8 3.6 1.4 1 0 0 1 1 1 1 Right handed beta helix region Pectate_lyase_3 PF12708.7 KFM67016.1 - 0.0014 18.5 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 Pectate lyase superfamily protein NosD PF05048.13 KFM67016.1 - 0.015 14.6 1.8 0.03 13.6 1.8 1.5 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF3452 PF11934.8 KFM67017.1 - 0.034 13.7 0.2 0.048 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF4210 PF13915.6 KFM67019.1 - 6.6e-12 45.9 0.0 3.4e-11 43.6 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KFM67020.1 - 3.2e-13 49.6 0.0 5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Chromosome segregation during meiosis Polysacc_lyase PF14099.6 KFM67020.1 - 0.034 14.0 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase HTH_Tnp_Tc3_2 PF01498.18 KFM67021.1 - 5.4e-06 26.6 0.1 7.7e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Transposase HRG PF16954.5 KFM67022.1 - 5.3e-05 23.5 0.3 5.3e-05 23.5 0.3 3.0 2 1 1 3 3 3 1 Haem-transporter, endosomal/lysosomal, haem-responsive gene GpcrRhopsn4 PF10192.9 KFM67022.1 - 0.037 13.4 4.8 0.047 13.1 4.8 1.1 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain DUF4131 PF13567.6 KFM67022.1 - 0.071 12.8 4.2 0.074 12.7 3.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Per1 PF04080.13 KFM67022.1 - 0.095 12.5 2.6 0.11 12.2 2.6 1.1 1 0 0 1 1 1 0 Per1-like family CYYR1 PF10873.8 KFM67022.1 - 0.21 12.0 1.2 0.31 11.5 0.2 1.7 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF2157 PF09925.9 KFM67022.1 - 0.97 9.2 7.2 2.8 7.7 7.2 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF4656 PF15551.6 KFM67023.1 - 0.11 11.9 1.6 0.12 11.9 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) RT_RNaseH_2 PF17919.1 KFM67025.1 - 6.7e-27 93.5 0.0 2.2e-26 91.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM67025.1 - 1.9e-25 89.2 0.0 7.2e-25 87.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Rib_recp_KP_reg PF05104.12 KFM67025.1 - 0.3 12.1 4.2 34 5.4 3.6 2.3 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region AA_permease PF00324.21 KFM67026.1 - 4.8e-21 74.9 9.6 3.2e-10 39.2 5.0 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFM67027.1 - 5.4e-12 45.1 0.6 6.2e-12 44.9 0.6 1.1 1 0 0 1 1 1 1 Amino acid permease EI24 PF07264.11 KFM67027.1 - 0.039 14.2 0.9 0.048 13.9 0.9 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) HTH_Tnp_Tc3_2 PF01498.18 KFM67028.1 - 2.6e-16 59.6 2.8 4.8e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67028.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67028.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67028.1 - 0.0023 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67028.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67029.1 - 4.4e-16 58.9 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67029.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67029.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67029.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67029.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain CUB PF00431.20 KFM67032.1 - 1.1e-58 196.3 0.8 2.5e-18 66.4 0.1 4.2 4 0 0 4 4 4 4 CUB domain RVT_1 PF00078.27 KFM67033.1 - 6.1e-33 114.2 0.2 1.2e-32 113.3 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Destabilase PF05497.12 KFM67035.1 - 2e-38 131.3 11.2 2.7e-38 130.9 11.2 1.1 1 0 0 1 1 1 1 Destabilase zf-H2C2_2 PF13465.6 KFM67036.1 - 1.2e-18 66.6 19.6 3.6e-08 33.5 0.7 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM67036.1 - 2.9e-11 43.2 28.2 0.00035 21.1 0.7 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM67036.1 - 4.3e-09 36.3 30.6 0.00036 20.8 0.5 4.2 4 0 0 4 4 3 3 Zinc finger, C2H2 type GAGA PF09237.11 KFM67036.1 - 3.4e-06 26.7 6.0 0.002 17.9 0.1 3.2 1 1 1 3 3 3 2 GAGA factor zf-Di19 PF05605.12 KFM67036.1 - 5.3e-05 23.4 10.7 0.0058 16.9 0.2 3.4 1 1 3 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 KFM67036.1 - 0.0004 20.1 4.6 0.25 11.2 0.0 3.0 4 0 0 4 4 2 2 Rad50 zinc hook motif zf-met PF12874.7 KFM67036.1 - 0.00046 20.5 0.4 0.00046 20.5 0.4 4.4 4 1 1 5 5 5 1 Zinc-finger of C2H2 type TRAF6_Z2 PF18048.1 KFM67036.1 - 0.001 19.1 9.2 0.032 14.3 0.3 3.6 3 0 0 3 3 3 1 TNF receptor-associated factor 6 zinc finger 2 Zn-C2H2_12 PF18112.1 KFM67036.1 - 0.0013 19.2 6.6 0.97 10.0 0.1 4.0 4 0 0 4 4 4 2 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_jaz PF12171.8 KFM67036.1 - 0.0014 18.8 18.8 0.045 14.1 0.3 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KFM67036.1 - 0.0021 18.3 7.6 0.43 10.9 0.1 3.9 4 0 0 4 4 3 1 zinc-ribbon Zn-ribbon_8 PF09723.10 KFM67036.1 - 0.0072 16.4 1.9 0.0072 16.4 1.9 3.2 2 2 0 2 2 2 1 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 KFM67036.1 - 0.0078 16.1 1.7 0.0078 16.1 1.7 3.3 3 0 0 3 3 3 1 SprT-like zinc ribbon domain DUF629 PF04780.12 KFM67036.1 - 0.009 14.6 0.2 0.009 14.6 0.2 2.4 1 1 1 3 3 3 1 Protein of unknown function (DUF629) zf-RING_2 PF13639.6 KFM67036.1 - 0.024 15.0 16.2 0.49 10.8 2.7 2.4 2 0 0 2 2 2 0 Ring finger domain HypA PF01155.19 KFM67036.1 - 0.039 14.0 5.7 0.084 12.9 0.5 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 KFM67036.1 - 0.04 14.6 4.6 2 9.2 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF1178 PF06676.11 KFM67036.1 - 0.042 14.2 3.2 0.22 11.9 0.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1178) ADK_lid PF05191.14 KFM67036.1 - 0.045 13.8 3.5 0.48 10.4 0.4 2.9 1 1 1 2 2 2 0 Adenylate kinase, active site lid C1_1 PF00130.22 KFM67036.1 - 0.059 13.3 18.3 0.29 11.1 1.5 3.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_6 PF13912.6 KFM67036.1 - 0.088 12.8 0.3 0.088 12.8 0.3 4.6 5 1 0 5 5 5 0 C2H2-type zinc finger Rtf2 PF04641.12 KFM67036.1 - 0.11 11.8 3.7 0.41 10.0 0.5 2.5 1 1 1 2 2 2 0 Rtf2 RING-finger zf-C2H2_2 PF12756.7 KFM67036.1 - 0.12 12.8 0.2 0.12 12.8 0.2 3.8 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-RING_5 PF14634.6 KFM67036.1 - 0.12 12.4 15.3 0.18 11.8 1.1 2.8 2 1 0 2 2 2 0 zinc-RING finger domain UBZ_FAAP20 PF15750.5 KFM67036.1 - 0.26 11.3 7.2 0.38 10.7 0.4 3.0 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf_UBZ PF18439.1 KFM67036.1 - 0.33 10.6 6.5 2.1 8.0 0.1 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Ephrin_rec_like PF07699.13 KFM67036.1 - 0.38 10.6 11.6 1 9.1 3.3 3.7 3 1 0 3 3 3 0 Putative ephrin-receptor like DUF2225 PF09986.9 KFM67036.1 - 0.41 10.3 6.1 2 8.1 0.2 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Prok-RING_4 PF14447.6 KFM67036.1 - 0.9 9.5 16.3 2.1 8.3 7.2 3.3 2 2 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.7 KFM67036.1 - 1.4 9.0 13.5 60 3.8 13.5 2.9 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 KFM67036.1 - 3.7 7.8 14.1 0.079 13.1 6.0 2.5 1 1 1 2 2 1 0 FYVE zinc finger zf-LYAR PF08790.11 KFM67036.1 - 6.2 6.8 12.1 5.9 6.9 0.2 4.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_9 PF16293.5 KFM67036.1 - 7 6.6 8.7 13 5.7 0.0 3.6 2 2 1 3 3 3 0 C2H2 type zinc-finger (1 copy) YdjO PF14169.6 KFM67036.1 - 9.6 6.0 11.5 6.1 6.7 0.6 3.6 2 1 2 4 4 4 0 Cold-inducible protein YdjO DUF2197 PF09963.9 KFM67036.1 - 9.6 6.6 11.3 13 6.1 1.2 3.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2H2 PF00096.26 KFM67037.1 - 1.5e-09 37.8 12.3 1.1e-05 25.6 3.3 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67037.1 - 1.6e-09 37.8 10.4 7.2e-05 23.3 2.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM67037.1 - 1.9e-09 37.5 5.9 1.7e-08 34.5 0.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM67037.1 - 2.2e-08 33.7 14.7 4e-08 32.9 2.4 2.7 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf-CHCC PF10276.9 KFM67037.1 - 4.4e-07 29.8 2.6 0.00071 19.6 0.2 2.2 2 0 0 2 2 2 2 Zinc-finger domain zf-Di19 PF05605.12 KFM67037.1 - 4.3e-05 23.7 4.7 0.00039 20.6 3.2 2.1 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_7 PF02591.15 KFM67037.1 - 5.1e-05 23.4 1.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 2 C4-type zinc ribbon domain zf-C2HC_2 PF13913.6 KFM67037.1 - 0.0005 19.9 8.0 0.0019 18.1 1.0 2.6 3 0 0 3 3 2 1 zinc-finger of a C2HC-type TRAF6_Z2 PF18048.1 KFM67037.1 - 0.00088 19.3 2.4 0.16 12.1 0.2 2.6 2 1 0 2 2 2 1 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_2 PF12756.7 KFM67037.1 - 0.00093 19.5 4.3 0.36 11.2 0.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM67037.1 - 0.002 18.8 0.1 0.0024 18.6 0.1 1.1 1 0 0 1 1 1 1 zinc-ribbon family CpXC PF14353.6 KFM67037.1 - 0.008 16.2 2.1 1.6 8.8 0.2 2.0 1 1 1 2 2 2 2 CpXC protein zf-C2H2_9 PF16293.5 KFM67037.1 - 0.011 15.5 0.5 1.1 9.2 0.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) FYDLN_acid PF09538.10 KFM67037.1 - 0.012 16.3 1.0 0.35 11.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Sgf11 PF08209.11 KFM67037.1 - 0.014 15.0 4.1 1.8 8.2 0.4 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Prok-RING_4 PF14447.6 KFM67037.1 - 0.015 15.1 0.5 0.7 9.8 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-BED PF02892.15 KFM67037.1 - 0.02 14.9 7.0 0.28 11.2 0.7 2.3 1 1 1 2 2 2 0 BED zinc finger zf-TRAF PF02176.18 KFM67037.1 - 0.022 15.4 3.5 0.029 15.0 3.5 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger FANCL_C PF11793.8 KFM67037.1 - 0.023 14.9 1.3 3.5 7.9 0.1 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain DZR PF12773.7 KFM67037.1 - 0.03 14.3 3.1 0.15 12.1 3.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-ISL3 PF14690.6 KFM67037.1 - 0.03 15.0 6.7 0.43 11.3 3.1 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-C2H2_12 PF18112.1 KFM67037.1 - 0.032 14.7 6.3 2 8.9 0.2 3.0 2 2 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain PyrI_C PF02748.15 KFM67037.1 - 0.054 13.4 0.4 4.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TF_Zn_Ribbon PF08271.12 KFM67037.1 - 0.058 12.9 0.5 4.2 7.0 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Cys_rich_CPXG PF14255.6 KFM67037.1 - 0.059 13.3 4.5 1.9 8.5 0.3 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG HypA PF01155.19 KFM67037.1 - 0.07 13.2 0.1 0.079 13.0 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rad50_zn_hook PF04423.14 KFM67037.1 - 0.074 12.9 0.5 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif Cys_rich_KTR PF14205.6 KFM67037.1 - 0.081 12.7 1.1 0.27 11.1 1.0 1.8 1 1 1 2 2 2 0 Cysteine-rich KTR zf_C2H2_6 PF18450.1 KFM67037.1 - 0.088 12.5 4.9 2 8.2 0.5 2.4 2 0 0 2 2 2 0 Zinc Finger domain zf-LITAF-like PF10601.9 KFM67037.1 - 0.11 12.8 3.6 3.2 8.1 0.3 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.6 KFM67037.1 - 0.24 10.8 8.4 0.76 9.3 0.2 2.5 3 0 0 3 3 2 0 zinc-ribbon domain RNHCP PF12647.7 KFM67037.1 - 0.29 11.1 5.6 0.44 10.5 1.0 2.1 1 1 1 2 2 2 0 RNHCP domain zinc_ribbon_2 PF13240.6 KFM67037.1 - 0.32 10.8 5.6 1.7 8.5 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFM67037.1 - 0.77 9.8 10.5 4 7.5 0.5 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFM67037.1 - 1.2 9.2 9.3 0.73 9.8 4.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain GAGA PF09237.11 KFM67037.1 - 2.3 8.1 7.2 0.75 9.6 2.4 2.0 1 1 1 2 2 2 0 GAGA factor FYVE PF01363.21 KFM67037.1 - 5.8 7.1 10.2 1.9 8.7 5.4 1.9 1 1 0 1 1 1 0 FYVE zinc finger PIG-Y PF15159.6 KFM67038.1 - 0.082 13.8 0.1 0.17 12.8 0.1 1.5 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y TMEM174 PF15029.6 KFM67038.1 - 0.55 9.9 3.3 0.86 9.3 0.3 2.1 1 1 1 2 2 2 0 Transmembrane protein 174 Neur_chan_LBD PF02931.23 KFM67039.1 - 9.3e-07 28.5 0.0 9.3e-07 28.5 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain AMP-binding PF00501.28 KFM67040.1 - 5.2e-39 134.0 0.0 6.1e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM67040.1 - 1.1e-20 74.3 0.0 2.1e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFM67041.1 - 2.8e-26 92.1 0.0 3.2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Csm4_C PF17953.1 KFM67041.1 - 0.016 15.1 0.0 0.06 13.2 0.0 1.9 1 1 1 2 2 2 0 CRISPR Csm4 C-terminal domain DUF2963 PF11178.8 KFM67041.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) Sel1 PF08238.12 KFM67042.1 - 7.4e-18 64.6 18.2 8.2e-06 26.3 0.4 5.8 6 0 0 6 6 6 5 Sel1 repeat DUF4538 PF15061.6 KFM67044.1 - 2.5e-26 91.2 0.3 3.7e-26 90.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) PP2C PF00481.21 KFM67045.1 - 8.4e-45 153.4 0.1 9.5e-45 153.2 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFM67045.1 - 1.6e-08 34.4 0.2 2.8e-08 33.7 0.2 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C DUF5603 PF18231.1 KFM67045.1 - 0.0094 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5603) Dot_icm_IcmQ PF09475.10 KFM67045.1 - 0.087 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) PP2C PF00481.21 KFM67046.1 - 9e-05 22.2 0.6 0.00055 19.7 0.0 1.9 1 1 1 2 2 2 1 Protein phosphatase 2C Carboxyl_trans PF01039.22 KFM67047.1 - 3.6e-24 85.3 0.0 4.8e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Carboxyl_trans PF01039.22 KFM67048.1 - 5.1e-40 137.6 0.0 6.8e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain HTH_Tnp_Tc3_2 PF01498.18 KFM67050.1 - 1.7e-12 47.4 2.8 1.7e-12 47.4 2.8 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67050.1 - 4.5e-08 33.0 0.0 2.3e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM67050.1 - 0.077 13.6 1.2 0.077 13.6 1.2 2.9 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM67051.1 - 3.7e-16 59.2 0.1 5.7e-15 55.3 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67051.1 - 7.6e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM67051.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67051.1 - 0.0022 17.7 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67051.1 - 0.015 15.5 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM67051.1 - 0.033 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM67052.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67052.1 - 7.4e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67053.1 - 1.9e-16 60.0 2.2 4.2e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67053.1 - 9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM67055.1 - 1.8e-16 60.2 0.1 2.1e-15 56.7 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67055.1 - 1.2e-10 41.4 1.0 2.7e-10 40.4 1.0 1.6 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM67056.1 - 2e-16 60.0 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67056.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease FXa_inhibition PF14670.6 KFM67057.1 - 0.012 15.9 9.5 0.012 15.9 9.5 2.2 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.17 KFM67058.1 - 1.8e-28 98.7 1.0 4.3e-12 46.3 0.0 3.6 3 1 0 3 3 3 3 Low-density lipoprotein receptor repeat class B Ldl_recept_b PF00058.17 KFM67060.1 - 5.8e-07 29.9 0.1 9.7e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor repeat class B Ldl_recept_b PF00058.17 KFM67061.1 - 1.8e-34 117.9 10.7 4.6e-11 43.0 0.0 7.6 7 1 0 7 7 7 6 Low-density lipoprotein receptor repeat class B SGL PF08450.12 KFM67061.1 - 7.1e-07 29.1 0.6 0.55 9.8 0.0 4.2 3 2 0 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 KFM67061.1 - 7.2e-07 28.7 0.3 0.00025 20.4 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF5050) DUF4884 PF16225.5 KFM67061.1 - 0.013 15.5 0.2 0.032 14.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) EGF PF00008.27 KFM67061.1 - 4.2 7.8 15.3 9.4 6.6 15.3 1.6 1 0 0 1 1 1 0 EGF-like domain Ldl_recept_a PF00057.18 KFM67062.1 - 2.4e-47 158.9 70.3 1.8e-10 40.9 9.8 5.9 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 KFM67062.1 - 8.9e-05 22.7 4.2 8.9e-05 22.7 4.2 5.3 5 1 0 5 5 5 1 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.18 KFM67064.1 - 1.5e-117 383.5 190.0 8.2e-13 48.3 11.0 11.8 11 0 0 11 11 11 11 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFM67064.1 - 7.6e-36 122.3 10.9 4.3e-11 43.1 0.2 6.4 6 1 0 6 6 6 5 Low-density lipoprotein receptor repeat class B Ldl_recept_b PF00058.17 KFM67065.1 - 2.1e-27 95.3 2.3 1.3e-10 41.6 0.0 3.6 3 0 0 3 3 3 3 Low-density lipoprotein receptor repeat class B EGF PF00008.27 KFM67065.1 - 9e-20 70.7 152.0 1.5e-05 25.1 5.1 11.4 11 0 0 11 11 11 9 EGF-like domain hEGF PF12661.7 KFM67065.1 - 1.2e-13 51.1 112.5 0.00024 21.6 3.4 12.3 11 1 0 11 11 11 9 Human growth factor-like EGF EGF_2 PF07974.13 KFM67065.1 - 3.8e-11 43.1 154.5 0.0047 17.3 6.3 11.1 10 1 1 11 11 11 9 EGF-like domain SGL PF08450.12 KFM67065.1 - 0.0055 16.3 0.4 0.022 14.3 0.1 2.0 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region MLANA PF14991.6 KFM67065.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A DUF5050 PF16472.5 KFM67065.1 - 0.021 14.1 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) SKG6 PF08693.10 KFM67065.1 - 0.042 13.3 0.2 0.072 12.5 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Arylesterase PF01731.20 KFM67065.1 - 0.15 12.3 0.2 10 6.4 0.0 3.2 3 0 0 3 3 3 0 Arylesterase WD40 PF00400.32 KFM67066.1 - 6.6e-12 45.8 7.5 0.098 13.6 0.0 7.3 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM67066.1 - 0.00015 22.0 0.0 2.6 8.4 0.0 4.3 6 0 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Y_phosphatase2 PF03162.13 KFM67066.1 - 0.038 13.6 1.9 3.7 7.1 0.2 2.3 1 1 0 2 2 2 0 Tyrosine phosphatase family CDI PF02234.19 KFM67067.1 - 2.6e-12 46.7 0.3 6.4e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor Peptidase_M13 PF01431.21 KFM67068.1 - 4.7e-32 111.2 0.0 8.2e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM67068.1 - 7.5e-29 101.6 0.8 2.7e-28 99.7 0.8 1.8 1 1 0 1 1 1 1 Peptidase family M13 DAO PF01266.24 KFM67069.1 - 3.7e-60 204.4 0.0 4.9e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.21 KFM67069.1 - 4.8e-40 137.5 0.0 6.9e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain FAO_M PF16350.5 KFM67069.1 - 2.7e-20 72.5 0.2 2.7e-20 72.5 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 KFM67069.1 - 3.7e-05 23.1 0.1 0.032 13.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM67069.1 - 0.00024 20.4 0.4 0.034 13.4 0.3 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KFM67069.1 - 0.0003 21.3 0.4 0.8 10.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFM67069.1 - 0.0024 16.8 0.1 0.33 9.8 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KFM67069.1 - 0.0045 17.2 0.6 0.013 15.7 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFM67069.1 - 0.031 13.5 0.3 1.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM67069.1 - 0.032 13.3 0.6 7.1 5.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 KFM67069.1 - 0.071 12.4 0.6 0.84 8.9 0.0 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM67070.1 - 2e-16 60.0 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67070.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease ANF_receptor PF01094.28 KFM67071.1 - 4.8e-09 35.8 0.0 5.8e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Autophagy_C PF10381.9 KFM67073.1 - 0.036 13.6 0.3 0.074 12.6 0.3 1.6 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal PP2C PF00481.21 KFM67076.1 - 7.6e-19 68.3 0.3 1.6e-18 67.3 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.21 KFM67077.1 - 7.1e-15 55.3 0.1 7.9e-15 55.2 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Nitrate_red_del PF02613.15 KFM67077.1 - 0.0025 17.8 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Nitrate reductase delta subunit PCRF PF03462.18 KFM67077.1 - 0.065 13.1 0.1 0.098 12.5 0.1 1.3 1 1 0 1 1 1 0 PCRF domain Bac_surface_Ag PF01103.23 KFM67078.1 - 1.5e-48 166.0 0.0 1.8e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 KFM67078.1 - 0.011 16.2 0.1 0.019 15.5 0.1 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat 7tm_2 PF00002.24 KFM67079.1 - 9.2e-14 51.3 0.6 1.2e-13 51.0 0.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HTH_Tnp_Tc3_2 PF01498.18 KFM67080.1 - 4.5e-16 58.9 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67080.1 - 1.2e-13 51.1 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67080.1 - 1.8e-07 30.8 1.2 6.8e-07 28.9 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67080.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67080.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67081.1 - 5e-16 58.7 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67081.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67081.1 - 2e-07 30.7 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67081.1 - 0.0027 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67081.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain MMR_HSR1 PF01926.23 KFM67083.1 - 3.9e-09 36.6 0.0 3.1e-08 33.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM67083.1 - 1.5e-05 24.6 0.0 0.0034 16.9 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B PduV-EutP PF10662.9 KFM67083.1 - 0.0004 20.2 0.0 0.75 9.5 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KFM67083.1 - 0.00058 19.8 0.3 0.018 14.9 0.3 2.1 1 1 0 1 1 1 1 RsgA GTPase Ras PF00071.22 KFM67083.1 - 0.00096 18.8 0.0 0.31 10.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFM67083.1 - 0.0013 18.9 0.0 0.0035 17.6 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KFM67083.1 - 0.014 14.7 0.1 0.027 13.8 0.0 1.4 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 KFM67083.1 - 0.053 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KFM67083.1 - 0.074 12.5 0.0 6.9 6.1 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family TniB PF05621.11 KFM67083.1 - 0.095 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SWIM PF04434.17 KFM67084.1 - 0.001 18.7 2.2 0.001 18.7 2.2 2.4 2 0 0 2 2 2 1 SWIM zinc finger DUF684 PF05075.14 KFM67084.1 - 0.046 12.7 0.6 0.098 11.6 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF684) BLI1 PF17324.2 KFM67084.1 - 0.066 13.9 0.2 1.5 9.5 0.0 2.1 2 0 0 2 2 2 0 BLOC-1 interactor 1 DDE_3 PF13358.6 KFM67085.1 - 0.0002 21.1 0.1 0.00029 20.6 0.1 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease AI-2E_transport PF01594.16 KFM67086.1 - 1.6e-07 30.8 24.7 2.6e-07 30.1 18.3 2.4 2 1 0 2 2 2 2 AI-2E family transporter DUF1461 PF07314.11 KFM67086.1 - 0.11 12.3 5.0 3.6 7.5 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF3093 PF11292.8 KFM67086.1 - 0.59 10.4 0.0 0.59 10.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) AAA_18 PF13238.6 KFM67087.1 - 9.9e-28 97.3 0.0 1.4e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFM67087.1 - 4.2e-06 27.2 0.0 2.5e-05 24.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 KFM67087.1 - 2.6e-05 24.5 0.0 3.7e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFM67087.1 - 0.00015 22.2 0.0 0.001 19.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 KFM67087.1 - 0.00031 20.9 0.0 0.0037 17.4 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_16 PF13191.6 KFM67087.1 - 0.00066 20.1 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KFM67087.1 - 0.0008 19.4 0.2 0.0016 18.4 0.2 1.6 1 1 0 1 1 1 1 NTPase RNA_helicase PF00910.22 KFM67087.1 - 0.0009 19.6 0.1 0.0031 17.9 0.0 1.8 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KFM67087.1 - 0.0019 18.5 0.7 0.0046 17.2 0.2 1.9 2 1 0 2 2 1 1 AAA domain Cytidylate_kin PF02224.18 KFM67087.1 - 0.0032 17.2 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 KFM67087.1 - 0.0095 16.1 0.0 0.064 13.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM67087.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KFM67087.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 KFM67087.1 - 0.012 15.5 0.1 0.026 14.3 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 KFM67087.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KFM67087.1 - 0.017 15.2 0.1 0.026 14.6 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KFM67087.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KFM67087.1 - 0.024 13.9 0.4 0.066 12.4 0.2 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.22 KFM67087.1 - 0.026 14.6 0.1 3 8.0 0.0 2.3 1 1 1 2 2 2 0 Shikimate kinase MeaB PF03308.16 KFM67087.1 - 0.028 13.4 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KFM67087.1 - 0.028 14.1 0.7 0.053 13.2 0.2 1.9 2 2 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFM67087.1 - 0.029 14.4 0.0 0.074 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KFM67087.1 - 0.032 13.4 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 KFM67087.1 - 0.034 13.5 0.1 0.093 12.1 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.6 KFM67087.1 - 0.038 13.7 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KFM67087.1 - 0.052 12.6 0.1 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain DUF815 PF05673.13 KFM67087.1 - 0.059 12.5 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 KFM67087.1 - 0.08 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 KFM67087.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Lipase_GDSL_lke PF16255.5 KFM67087.1 - 0.092 12.1 0.4 0.29 10.5 0.4 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase T2SSE PF00437.20 KFM67087.1 - 0.092 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KFM67087.1 - 0.093 12.8 0.5 0.31 11.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFM67087.1 - 0.12 12.7 3.3 0.33 11.3 0.3 2.2 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 KFM67087.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 KFM67087.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFM67087.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM67087.1 - 0.22 12.1 0.4 0.26 11.8 0.4 1.5 1 1 0 1 1 1 0 ABC transporter YqaJ PF09588.10 KFM67088.1 - 2.6e-14 53.6 0.0 3.4e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain Viral_alk_exo PF01771.17 KFM67088.1 - 3.6e-07 29.4 0.3 1.2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Viral alkaline exonuclease HpaB_N PF11794.8 KFM67088.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DDE_Tnp_4 PF13359.6 KFM67089.1 - 1.2e-41 142.0 0.0 1.8e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KFM67089.1 - 7.1e-12 44.9 0.1 1.7e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KFM67089.1 - 9.4e-08 32.0 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Glyco_tran_28_C PF04101.16 KFM67090.1 - 2.9e-25 89.2 0.0 3.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM67091.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67091.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67091.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67091.1 - 0.0023 17.7 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67091.1 - 1.7 9.3 15.7 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67092.1 - 1.6e-13 50.7 2.3 2.2e-13 50.2 0.9 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67092.1 - 1.3e-12 47.6 0.0 3.8e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease PAX PF00292.18 KFM67092.1 - 0.00013 21.9 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.6 KFM67092.1 - 0.00032 20.7 2.3 0.027 14.6 0.1 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67092.1 - 0.00041 20.1 3.7 0.034 14.0 0.0 3.3 2 1 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KFM67092.1 - 0.00057 19.9 4.2 0.57 10.3 1.7 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM67092.1 - 0.0012 19.4 5.8 0.0012 19.4 5.8 3.7 3 1 1 4 4 4 1 Homeodomain-like domain HTH_29 PF13551.6 KFM67092.1 - 0.055 13.5 1.4 0.79 9.8 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn helix HTH_33 PF13592.6 KFM67092.1 - 0.068 12.8 0.2 0.27 10.9 0.2 2.0 1 0 0 1 1 1 0 Winged helix-turn helix HTH_22 PF13309.6 KFM67092.1 - 0.095 12.8 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 KFM67092.1 - 0.13 12.0 1.6 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 KFM67092.1 - 0.15 12.1 0.1 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Transposase Herpes_PAP PF03325.13 KFM67093.1 - 0.012 15.1 0.1 0.019 14.5 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein rve PF00665.26 KFM67093.1 - 0.045 14.0 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Integrase_H2C2 PF17921.1 KFM67094.1 - 0.014 15.4 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 Integrase zinc binding domain Arb2 PF09757.9 KFM67095.1 - 3.8e-06 26.2 0.0 5.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain PGAP1 PF07819.13 KFM67095.1 - 6.8e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFM67095.1 - 0.00081 20.1 0.0 0.0014 19.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM67095.1 - 0.0051 16.5 0.1 0.008 15.8 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM67095.1 - 0.0051 16.1 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 KFM67095.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 KFM67095.1 - 0.073 12.6 2.0 0.47 9.9 2.0 2.1 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.12 KFM67095.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase FMN_dh PF01070.18 KFM67096.1 - 2.2e-36 125.6 0.0 2.6e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1258 PF06869.12 KFM67096.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Osmo_CC PF08946.10 KFM67100.1 - 0.22 11.8 2.7 3.5 7.9 0.6 2.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil THAP PF05485.12 KFM67103.1 - 6.2e-07 30.3 0.2 4.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 THAP domain SRPRB PF09439.10 KFM67104.1 - 0.078 12.4 0.3 0.12 11.8 0.3 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NumbF PF06311.12 KFM67106.1 - 5e-36 123.1 3.8 9.9e-36 122.2 2.8 2.0 2 0 0 2 2 2 1 NUMB domain PID PF00640.23 KFM67106.1 - 5.9e-23 81.5 0.0 2.1e-22 79.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 KFM67106.1 - 5.6e-06 26.4 0.2 1.1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFM67106.1 - 0.084 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosine-binding domain ASC PF00858.24 KFM67107.1 - 2.8e-47 161.7 11.9 3.3e-47 161.5 11.9 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel SH3_1 PF00018.28 KFM67108.1 - 4.8e-11 42.1 0.0 8.2e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM67108.1 - 1.1e-10 41.2 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM67108.1 - 1.1e-08 34.6 0.0 1.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 KFM67108.1 - 0.024 15.2 0.0 0.047 14.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) ArfGap PF01412.18 KFM67109.1 - 1.4e-14 54.2 0.0 1.4e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-primase PF09329.11 KFM67111.1 - 0.0011 18.7 0.1 0.0012 18.6 0.1 1.2 1 0 0 1 1 1 1 Primase zinc finger TraB PF01963.17 KFM67113.1 - 1.8e-08 34.7 0.0 2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 TraB family CFTR_R PF14396.6 KFM67114.1 - 0.0083 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain HTH_32 PF13565.6 KFM67114.1 - 0.049 14.2 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67115.1 - 2.2e-16 59.9 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67115.1 - 9.1e-14 51.4 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease LRR_8 PF13855.6 KFM67116.1 - 4.7e-18 64.7 36.6 1.9e-11 43.6 6.7 4.9 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFM67116.1 - 8.5e-13 48.3 37.7 1.4e-05 25.3 4.2 5.3 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM67116.1 - 2.7e-08 33.8 0.3 6.5e-08 32.6 0.3 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM67116.1 - 1.7e-05 24.4 10.2 0.018 14.5 1.4 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFM67116.1 - 1.8e-05 24.7 27.6 0.013 15.9 0.1 7.8 7 1 0 7 7 7 3 Leucine Rich Repeat LRRNT PF01462.18 KFM67116.1 - 0.0007 19.2 2.1 0.0086 15.7 2.3 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFM67116.1 - 0.98 9.6 27.0 0.63 10.2 0.4 6.7 7 0 0 7 7 7 0 Leucine Rich repeat DUF782 PF05614.11 KFM67117.1 - 0.048 14.1 0.0 0.049 14.0 0.0 1.1 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) DUF3456 PF11938.8 KFM67118.1 - 2.4e-48 164.6 1.3 2.8e-48 164.4 1.3 1.1 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_1 PF05184.15 KFM67118.1 - 0.0047 16.9 0.9 0.063 13.3 0.3 2.6 2 0 0 2 2 2 1 Saposin-like type B, region 1 ETC_C1_NDUFA4 PF04800.12 KFM67119.1 - 7.1e-34 115.9 0.1 1.3e-33 115.1 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region EPTP PF03736.17 KFM67120.1 - 0.0014 18.6 0.1 0.0031 17.5 0.0 1.6 2 0 0 2 2 2 1 EPTP domain DSBA PF01323.20 KFM67121.1 - 5.1e-38 130.8 0.0 5.7e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain COMM_domain PF07258.14 KFM67122.1 - 7.3e-13 48.4 0.0 3e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 COMM domain FYVE PF01363.21 KFM67123.1 - 2.3e-19 69.3 0.8 5e-19 68.2 0.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 KFM67123.1 - 4.4e-14 51.9 2.8 7e-14 51.3 1.5 2.2 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-C2H2_9 PF16293.5 KFM67123.1 - 0.0028 17.5 0.2 0.041 13.7 0.0 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (1 copy) MCR_beta_N PF02783.15 KFM67123.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain zf-Di19 PF05605.12 KFM67123.1 - 0.15 12.3 0.2 0.15 12.3 0.2 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Spectrin PF00435.21 KFM67123.1 - 0.22 12.0 9.2 0.23 12.0 1.0 2.8 2 0 0 2 2 2 0 Spectrin repeat IBR PF01485.21 KFM67123.1 - 0.37 11.1 3.4 0.64 10.3 1.8 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 KFM67123.1 - 1.7 9.0 5.7 6.4 7.1 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon zf_C2HC_14 PF18574.1 KFM67123.1 - 1.8 8.4 6.3 0.44 10.4 2.5 1.9 2 0 0 2 2 2 0 C2HC Zing finger domain DBR1 PF05011.13 KFM67124.1 - 1.4e-36 126.0 0.1 2.9e-36 124.9 0.1 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KFM67124.1 - 9.4e-09 36.1 0.1 2e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM67124.1 - 0.036 14.3 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DDE_1 PF03184.19 KFM67125.1 - 0.022 14.4 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM67127.1 - 6.2e-46 152.8 49.7 7.6e-10 38.8 0.8 7.9 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67127.1 - 4.4e-30 102.4 55.0 4.6e-06 26.8 1.3 7.8 7 1 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67127.1 - 1.6e-28 96.9 49.2 0.00014 22.4 1.0 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM67127.1 - 3.1e-13 49.3 51.4 7.8e-08 32.1 0.4 7.2 8 0 0 8 8 7 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM67127.1 - 1.5e-11 43.8 28.6 0.0091 15.7 0.1 6.9 7 0 0 7 7 7 5 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM67127.1 - 3.4e-08 33.5 30.9 0.0038 17.5 0.1 7.1 7 1 1 8 8 7 3 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFM67127.1 - 1.1e-05 25.4 27.7 0.0019 18.2 0.6 5.3 4 2 0 5 5 5 3 Zinc ribbon domain zf-met PF12874.7 KFM67127.1 - 1.9e-05 24.9 3.4 0.00045 20.5 0.5 6.6 7 0 0 7 7 6 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM67127.1 - 7.9e-05 22.3 11.2 0.0044 16.7 5.6 7.7 8 1 0 8 8 7 2 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 KFM67127.1 - 0.00013 22.7 26.2 0.12 13.2 1.8 4.0 2 1 3 5 5 5 5 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM67127.1 - 0.00031 21.0 36.6 0.38 11.1 0.5 6.7 1 1 6 7 7 7 3 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM67127.1 - 0.00082 19.2 23.8 0.56 10.2 0.1 6.4 7 0 0 7 7 6 3 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM67127.1 - 0.002 17.7 24.6 3.3 7.4 0.1 7.0 7 1 0 7 7 7 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFM67127.1 - 0.0052 17.5 22.0 5.9 7.6 0.3 6.0 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 KFM67127.1 - 0.0067 16.8 37.2 0.13 12.7 2.6 6.7 2 2 5 7 7 7 2 C2HE / C2H2 / C2HC zinc-binding finger DUF3268 PF11672.8 KFM67127.1 - 0.015 15.6 19.8 0.12 12.7 0.4 4.4 3 1 1 4 4 4 0 zinc-finger-containing domain HypA PF01155.19 KFM67127.1 - 0.027 14.5 22.4 0.29 11.2 0.6 3.9 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA YhfH PF14149.6 KFM67127.1 - 0.057 13.4 1.3 0.057 13.4 1.3 5.2 6 0 0 6 6 5 0 YhfH-like protein zf-C2H2_8 PF15909.5 KFM67127.1 - 0.061 13.6 25.0 0.69 10.2 2.6 3.9 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 KFM67127.1 - 0.11 13.2 24.9 0.79 10.5 1.3 4.7 1 1 3 5 5 5 0 TRAF-type zinc finger DUF2688 PF10892.8 KFM67127.1 - 0.2 11.1 10.0 10 5.7 0.2 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) FYVE PF01363.21 KFM67127.1 - 0.24 11.6 35.9 1.5 9.0 3.8 4.5 1 1 3 4 4 4 0 FYVE zinc finger zf-BED PF02892.15 KFM67127.1 - 0.3 11.2 33.2 3 8.0 0.1 5.9 3 1 3 6 6 6 0 BED zinc finger zf-trcl PF13451.6 KFM67127.1 - 0.43 10.5 25.4 0.34 10.8 2.4 6.2 6 1 0 6 6 6 0 Probable zinc-ribbon domain GAGA PF09237.11 KFM67127.1 - 0.54 10.1 12.1 2.6 7.9 0.1 4.2 3 1 1 4 4 4 0 GAGA factor GATA PF00320.27 KFM67127.1 - 0.58 9.8 0.1 0.58 9.8 0.1 6.0 6 1 0 6 6 6 0 GATA zinc finger HalOD2 PF18547.1 KFM67127.1 - 0.62 10.0 19.4 0.12 12.3 3.5 4.1 4 1 0 4 4 4 0 Halobacterial output domain 2 BolA PF01722.18 KFM67127.1 - 1.2 9.5 8.9 9.8 6.5 0.2 3.7 4 0 0 4 4 4 0 BolA-like protein zf-AN1 PF01428.16 KFM67127.1 - 1.4 9.2 32.8 1.4 9.2 0.1 6.8 6 1 1 7 7 7 0 AN1-like Zinc finger LIM PF00412.22 KFM67127.1 - 1.6 9.0 30.2 0.3 11.4 4.0 4.8 2 1 2 5 5 5 0 LIM domain zinc-ribbons_6 PF07191.12 KFM67127.1 - 3.1 7.9 29.5 2.2e+02 1.9 0.9 4.9 1 1 2 3 3 2 0 zinc-ribbons zf-C2H2_9 PF16293.5 KFM67127.1 - 3.3 7.6 9.7 20 5.1 0.0 4.5 5 1 1 6 6 4 0 C2H2 type zinc-finger (1 copy) XPA_N PF01286.18 KFM67127.1 - 3.9 7.6 24.1 22 5.2 0.0 6.5 7 0 0 7 7 7 0 XPA protein N-terminal zf-MYST PF17772.1 KFM67127.1 - 4.1 7.1 22.1 2.2 7.9 0.2 5.3 5 2 1 6 6 5 0 MYST family zinc finger domain Ig_3 PF13927.6 KFM67128.1 - 6.9e-23 81.0 0.3 1.3e-12 48.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM67128.1 - 8.4e-18 64.2 0.1 3.9e-09 36.4 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM67128.1 - 3.9e-15 55.8 0.0 1.3e-09 38.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM67128.1 - 3.2e-14 53.0 0.1 3.7e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM67128.1 - 5.7e-09 35.9 0.0 1.6e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM67128.1 - 0.0022 18.2 0.2 1.2 9.4 0.1 2.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFM67128.1 - 0.0082 16.2 0.4 0.094 12.8 0.2 2.3 2 1 0 2 2 2 1 C17orf99 Ig domain CnrY PF17524.2 KFM67128.1 - 0.013 15.7 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma factor CnrY Ig_6 PF18452.1 KFM67128.1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain V-set_CD47 PF08204.11 KFM67128.1 - 0.068 13.1 0.0 0.14 12.2 0.0 1.5 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFM67128.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Adenovirus E3 region protein CR1 DUF1736 PF08409.11 KFM67129.1 - 2.5e-31 107.5 1.2 6.4e-31 106.2 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) DUF4371 PF14291.6 KFM67130.1 - 9.6e-11 41.8 0.0 5.3e-10 39.3 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4371) IGR PF09597.10 KFM67130.1 - 0.13 12.4 0.1 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 IGR protein motif HTH_Tnp_Tc3_2 PF01498.18 KFM67131.1 - 1.7e-17 63.4 1.7 5.2e-16 58.6 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67131.1 - 1.2e-13 51.0 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CUB PF00431.20 KFM67132.1 - 4.7e-10 39.8 0.0 6.8e-06 26.4 0.0 2.1 1 1 1 2 2 2 2 CUB domain CUB PF00431.20 KFM67133.1 - 2.6e-05 24.5 0.0 0.34 11.3 0.0 3.7 3 0 0 3 3 3 3 CUB domain HTH_Tnp_Tc3_2 PF01498.18 KFM67134.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67134.1 - 8.3e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67135.1 - 5.4e-16 58.6 3.5 6e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67135.1 - 9.8e-14 51.3 0.0 2.4e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67135.1 - 2.3e-07 30.5 1.2 7.4e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67135.1 - 0.0028 17.4 0.6 0.008 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67135.1 - 0.029 14.5 0.4 0.095 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM67135.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF4258 PF14076.6 KFM67136.1 - 0.1 13.0 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) UPF0547 PF10571.9 KFM67137.1 - 6.7e-08 32.5 12.9 9.8e-08 32.0 12.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 AT_hook PF02178.19 KFM67137.1 - 0.005 16.6 1.4 0.022 14.6 1.4 2.1 1 0 0 1 1 1 1 AT hook motif S36_mt PF10937.8 KFM67137.1 - 0.086 14.4 3.0 0.15 13.7 2.9 1.5 1 1 0 1 1 1 0 Ribosomal protein S36, mitochondrial ENT PF03735.14 KFM67138.1 - 1.9e-26 91.9 0.5 4.4e-26 90.7 0.5 1.7 1 0 0 1 1 1 1 ENT domain DHR-2 PF06920.13 KFM67140.1 - 3.2e-34 118.5 0.1 3.6e-34 118.3 0.1 1.0 1 0 0 1 1 1 1 Dock homology region 2 RNase_Zc3h12a PF11977.8 KFM67140.1 - 0.013 15.2 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain DHR-2 PF06920.13 KFM67141.1 - 1.4e-145 486.0 10.2 1.8e-145 485.6 10.2 1.2 1 0 0 1 1 1 1 Dock homology region 2 AAA_27 PF13514.6 KFM67142.1 - 0.0025 17.4 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain DOCK-C2 PF14429.6 KFM67143.1 - 3.3e-14 53.2 0.0 3.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins PC4 PF02229.16 KFM67144.1 - 2.1e-06 27.3 0.2 3.1e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) Mis12 PF05859.12 KFM67144.1 - 0.088 12.9 1.3 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 Mis12 protein Alliinase_C PF04864.13 KFM67145.1 - 0.18 10.6 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Allinase HTH_Tnp_Tc3_2 PF01498.18 KFM67146.1 - 2.6e-16 59.6 2.2 4.8e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67146.1 - 1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Na_Ca_ex PF01699.24 KFM67147.1 - 8.6e-20 71.2 1.0 9e-20 71.2 1.0 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 KFM67148.1 - 0.002 18.1 7.3 0.0028 17.6 7.3 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF5317 PF17248.2 KFM67148.1 - 0.052 13.6 2.2 0.072 13.1 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5317) Na_Ca_ex PF01699.24 KFM67149.1 - 2.3e-10 40.6 0.7 2.9e-10 40.3 0.7 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein zf-H2C2_5 PF13909.6 KFM67149.1 - 0.034 13.9 1.0 4.7 7.1 1.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF4834 PF16118.5 KFM67150.1 - 0.0085 17.0 0.1 0.017 16.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF2534 PF10749.9 KFM67150.1 - 0.054 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) Comm PF15957.5 KFM67150.1 - 0.067 13.5 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 Commissureless MLANA PF14991.6 KFM67150.1 - 0.099 12.9 0.4 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein melan-A WBP-1 PF11669.8 KFM67150.1 - 0.11 13.2 2.7 0.64 10.7 0.3 2.8 2 1 1 3 3 3 0 WW domain-binding protein 1 HemY_N PF07219.13 KFM67150.1 - 0.15 12.3 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Shisa PF13908.6 KFM67150.1 - 0.36 11.0 5.8 0.098 12.9 0.9 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator AAA PF00004.29 KFM67153.1 - 2.7e-40 137.8 0.9 5.4e-40 136.9 0.0 2.0 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFM67153.1 - 4.1e-26 90.8 0.3 1.8e-25 88.7 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KFM67153.1 - 1.1e-23 83.0 8.9 2.9e-23 81.7 8.9 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KFM67153.1 - 1.8e-09 37.2 0.0 6.5e-09 35.5 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFM67153.1 - 1.7e-05 25.1 0.5 0.0077 16.5 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KFM67153.1 - 4.1e-05 23.8 0.1 0.0006 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFM67153.1 - 5.4e-05 23.6 0.2 0.0052 17.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 KFM67153.1 - 6.2e-05 22.4 0.0 9.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KFM67153.1 - 7.3e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFM67153.1 - 8.2e-05 22.6 0.0 0.0003 20.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KFM67153.1 - 9e-05 22.3 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KFM67153.1 - 0.00043 20.3 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFM67153.1 - 0.0012 18.1 0.0 0.0026 17.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFM67153.1 - 0.0025 18.3 1.5 0.0057 17.2 0.0 2.5 3 1 0 3 3 2 1 AAA domain LRRC37AB_C PF14914.6 KFM67153.1 - 0.0033 17.3 1.0 0.0064 16.4 1.0 1.4 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain AAA_33 PF13671.6 KFM67153.1 - 0.0036 17.5 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Tae4 PF14113.6 KFM67153.1 - 0.013 15.8 0.3 0.029 14.6 0.3 1.6 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 RNA_helicase PF00910.22 KFM67153.1 - 0.015 15.7 0.0 0.041 14.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KFM67153.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFM67153.1 - 0.02 14.4 0.0 0.055 13.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFM67153.1 - 0.021 14.4 0.2 0.21 11.1 0.1 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KFM67153.1 - 0.03 14.3 0.0 0.39 10.6 0.0 2.3 1 1 0 1 1 1 0 NACHT domain TniB PF05621.11 KFM67153.1 - 0.033 13.6 0.0 3.4 7.0 0.0 2.5 1 1 0 2 2 2 0 Bacterial TniB protein AAA_11 PF13086.6 KFM67153.1 - 0.037 13.8 3.6 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFM67153.1 - 0.04 13.6 0.1 0.28 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 KFM67153.1 - 0.042 13.3 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.6 KFM67153.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 KFM67153.1 - 0.054 12.8 1.6 6.8 6.0 0.0 2.6 2 1 1 3 3 3 0 KaiC Sigma54_activat PF00158.26 KFM67153.1 - 0.1 12.3 0.0 0.43 10.3 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KFM67153.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PPL5 PF18168.1 KFM67153.1 - 0.13 11.5 2.4 0.22 10.8 2.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Torsin PF06309.11 KFM67153.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 Torsin Vfa1 PF08432.10 KFM67153.1 - 0.2 11.9 9.5 0.7 10.2 9.7 1.8 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 Cwf_Cwc_15 PF04889.12 KFM67153.1 - 0.23 11.2 10.4 0.42 10.3 10.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zn_ribbon_17 PF17120.5 KFM67154.1 - 6.4e-11 41.7 18.1 6.4e-11 41.7 18.1 2.2 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 KFM67154.1 - 1.2e-06 28.8 7.1 1.2e-06 28.8 7.1 3.0 1 1 1 2 2 2 1 Zinc-ribbon like family HDC PF02329.16 KFM67154.1 - 0.0069 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Histidine carboxylase PI chain COX6A PF02046.15 KFM67154.1 - 0.025 15.0 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa RWD PF05773.22 KFM67155.1 - 0.00078 19.7 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain eIF2A PF08662.11 KFM67156.1 - 1.2e-05 25.3 0.1 0.05 13.5 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFM67156.1 - 0.0033 17.7 3.4 1.2 9.4 0.2 2.9 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM67156.1 - 0.0055 17.5 10.8 0.34 11.8 0.6 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Homeodomain PF00046.29 KFM67159.1 - 2.2e-60 200.4 21.0 1.3e-16 60.1 0.5 4.9 4 0 0 4 4 4 4 Homeodomain zf-C2H2_4 PF13894.6 KFM67159.1 - 1.5e-14 53.4 147.0 0.053 14.4 0.2 24.3 25 0 0 25 25 25 13 C2H2-type zinc finger Homeobox_KN PF05920.11 KFM67159.1 - 2.4e-12 46.6 2.0 0.0087 15.9 0.0 4.9 4 0 0 4 4 4 4 Homeobox KN domain zf-C2H2 PF00096.26 KFM67159.1 - 2.1e-11 43.6 180.1 0.0081 16.6 0.7 24.0 27 0 0 27 27 26 12 Zinc finger, C2H2 type zf-Di19 PF05605.12 KFM67159.1 - 3.7e-05 23.9 5.4 3.7e-05 23.9 5.4 13.5 15 2 2 17 17 15 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFM67159.1 - 0.00029 20.5 1.3 0.00029 20.5 1.3 11.3 11 0 0 11 11 10 4 C2H2-type zinc-finger domain zf-met PF12874.7 KFM67159.1 - 0.00038 20.7 1.1 0.00038 20.7 1.1 17.1 18 1 0 18 18 17 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM67159.1 - 0.005 16.8 1.4 0.012 15.5 1.6 16.4 18 0 0 18 18 18 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM67159.1 - 0.0081 15.9 0.3 0.0081 15.9 0.3 10.7 13 0 0 13 13 11 1 zinc-finger C2H2-type LIM_bind PF01803.16 KFM67159.1 - 0.067 12.7 0.0 0.067 12.7 0.0 4.0 4 1 0 4 4 4 0 LIM-domain binding protein zf_C2H2_10 PF18414.1 KFM67159.1 - 4.8 6.8 15.9 6.1 6.5 1.2 5.9 5 0 0 5 5 5 0 C2H2 type zinc-finger DUF3808 PF10300.9 KFM67162.1 - 3e-37 128.5 0.0 3.5e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF3808 PF10300.9 KFM67163.1 - 1.1e-58 199.2 0.8 1.9e-58 198.4 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KFM67163.1 - 3.6e-07 29.8 4.4 0.39 11.0 0.2 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM67163.1 - 8e-05 22.9 1.8 0.0019 18.4 0.9 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM67163.1 - 0.00019 22.0 0.0 0.63 10.7 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM67163.1 - 0.00027 21.4 0.6 6.3 7.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM67163.1 - 0.0006 19.8 5.9 0.034 14.4 0.7 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM67163.1 - 0.0032 16.9 0.6 0.022 14.1 0.4 2.0 2 0 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 KFM67163.1 - 0.0075 17.0 0.6 29 5.9 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM67163.1 - 0.022 14.5 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_10 PF13374.6 KFM67163.1 - 0.053 13.4 0.4 0.71 9.8 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM67163.1 - 0.16 12.7 6.1 0.32 11.7 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFM67163.1 - 0.2 12.4 0.1 1.6 9.6 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM67163.1 - 0.29 11.0 8.9 6.6 6.7 0.3 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat DDE_3 PF13358.6 KFM67165.1 - 2.5e-06 27.3 0.0 2.5e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease I-set PF07679.16 KFM67166.1 - 5e-43 145.1 0.0 7.4e-16 58.0 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM67166.1 - 4.6e-39 132.9 0.1 3.4e-13 50.0 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM67166.1 - 2.1e-30 104.9 0.0 4.8e-12 46.0 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM67166.1 - 2.4e-25 88.5 0.0 1e-09 38.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM67166.1 - 6.6e-09 35.9 2.3 0.17 12.0 0.0 5.3 4 2 1 5 5 5 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM67166.1 - 9.8e-08 32.3 0.0 0.042 14.2 0.0 3.7 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM67166.1 - 3.5e-05 23.8 0.0 0.045 13.8 0.0 3.0 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM67166.1 - 0.0019 18.4 0.0 0.84 9.9 0.0 3.5 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFM67166.1 - 0.0027 17.2 0.0 0.18 11.4 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM67166.1 - 0.0066 16.5 0.5 3 8.0 0.0 3.3 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 KFM67166.1 - 0.17 12.1 0.0 39 4.5 0.0 3.2 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Kelch_1 PF01344.25 KFM67167.1 - 6.2e-21 73.7 2.1 1.8e-07 30.6 0.0 5.5 4 1 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KFM67167.1 - 1.8e-20 72.5 0.4 8.4e-06 25.9 0.0 5.0 3 2 2 5 5 5 4 Kelch motif BTB PF00651.31 KFM67167.1 - 1.3e-17 64.0 0.2 4.5e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM67167.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 0.3 2.3 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFM67167.1 - 2e-07 30.9 0.2 0.0012 18.8 0.0 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 KFM67167.1 - 1.6e-06 27.8 0.0 0.0087 16.0 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 KFM67167.1 - 0.12 12.7 0.1 55 4.2 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain HTH_Tnp_Tc3_2 PF01498.18 KFM67169.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67169.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67169.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67169.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67169.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67170.1 - 6.9e-16 58.3 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67170.1 - 7.1e-16 58.3 0.1 9.5e-15 54.6 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM67170.1 - 0.00068 20.2 1.5 0.00068 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67170.1 - 0.0021 17.8 0.1 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67170.1 - 0.012 15.8 0.1 0.061 13.5 0.1 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM67170.1 - 0.03 14.3 2.6 0.033 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM67171.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67171.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67171.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67171.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67171.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Pathogen_betaC1 PF09593.10 KFM67172.1 - 0.11 12.4 0.0 19 5.2 0.0 2.2 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein ASC PF00858.24 KFM67173.1 - 0.00022 20.3 2.4 0.00025 20.1 2.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel fn3 PF00041.21 KFM67174.1 - 2.9e-12 46.8 0.6 0.00033 20.9 0.1 3.4 3 0 0 3 3 3 3 Fibronectin type III domain HTH_Tnp_Tc3_2 PF01498.18 KFM67175.1 - 5.3e-16 58.6 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67175.1 - 5.8e-13 48.8 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67175.1 - 2.8e-07 30.2 0.2 7e-07 28.9 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67175.1 - 0.0028 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67175.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain MMgT PF10270.9 KFM67176.1 - 1.3e-14 54.3 0.0 1.7e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Tnp_P_element PF12017.8 KFM67178.1 - 1e-06 28.4 0.1 1.1e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Transposase protein DUF4603 PF15376.6 KFM67178.1 - 0.039 11.4 0.0 0.04 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DDE_Tnp_1_7 PF13843.6 KFM67179.1 - 5.1e-83 279.3 0.5 6.1e-83 279.0 0.5 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM67179.1 - 3.5e-05 24.5 7.9 3.5e-05 24.5 7.9 1.9 2 0 0 2 2 2 1 DDE_Tnp_1-like zinc-ribbon zf-B_box PF00643.24 KFM67179.1 - 0.05 13.8 3.2 0.098 12.8 3.2 1.4 1 0 0 1 1 1 0 B-box zinc finger IBR PF01485.21 KFM67179.1 - 0.13 12.5 6.4 0.36 11.1 6.4 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain C1_2 PF03107.16 KFM67179.1 - 1.3 9.4 7.3 3.2 8.2 7.3 1.7 1 1 0 1 1 1 0 C1 domain PHD PF00628.29 KFM67179.1 - 3.7 7.5 8.1 0.92 9.5 4.2 2.0 2 0 0 2 2 2 0 PHD-finger DDE_3 PF13358.6 KFM67180.1 - 3.3e-15 56.1 0.0 5.6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67181.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67181.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67181.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67181.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67181.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67182.1 - 1.7e-16 60.2 2.3 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67182.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease An_peroxidase PF03098.15 KFM67183.1 - 1.9e-90 304.0 0.0 2.3e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase CDC73_N PF16050.5 KFM67185.1 - 4.5e-60 203.5 0.2 4.5e-60 203.5 0.2 3.5 1 1 1 3 3 3 1 Paf1 complex subunit CDC73 N-terminal Abhydrolase_1 PF00561.20 KFM67186.1 - 1.1e-08 35.1 0.1 2.1e-08 34.2 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM67186.1 - 3.2e-07 29.9 0.0 4.9e-06 26.0 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM67186.1 - 0.0012 19.5 0.0 0.0018 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFM67186.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DNase-RNase PF02577.14 KFM67186.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Bifunctional nuclease GIY-YIG PF01541.24 KFM67187.1 - 1.2e-15 57.5 0.0 2.1e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 KFM67187.1 - 0.00091 19.4 1.7 0.00091 19.4 1.7 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFM67187.1 - 0.0013 18.9 1.1 0.003 17.7 1.1 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING-like PF08746.11 KFM67187.1 - 0.0018 18.6 3.5 0.0018 18.6 3.5 2.3 2 1 0 2 2 2 1 RING-like domain PHD PF00628.29 KFM67187.1 - 0.002 18.0 3.3 0.0052 16.6 3.3 1.8 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 KFM67187.1 - 0.0023 18.1 9.9 0.0023 18.0 3.5 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain T5orf172 PF10544.9 KFM67187.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.5 1 1 0 1 1 1 0 T5orf172 domain MUG113 PF13455.6 KFM67187.1 - 0.13 13.0 0.0 0.49 11.1 0.0 2.0 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 C1_1 PF00130.22 KFM67187.1 - 0.86 9.5 6.4 0.13 12.2 1.8 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 KFM67187.1 - 0.9 9.9 8.6 0.48 10.8 6.3 1.8 2 0 0 2 2 2 0 Ring finger domain zf_CCCH_4 PF18345.1 KFM67188.1 - 2.9e-12 46.2 48.3 2.4e-05 24.2 9.4 4.4 4 0 0 4 4 4 3 Zinc finger domain zf-CHY PF05495.12 KFM67188.1 - 1.3e-11 44.8 11.0 1.3e-11 44.8 11.0 5.2 5 1 0 5 5 5 2 CHY zinc finger zf-CCCH PF00642.24 KFM67188.1 - 2.2e-11 43.4 33.6 2.6e-06 27.2 5.0 4.2 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFM67188.1 - 7.3e-10 39.5 22.8 0.0001 22.9 3.4 4.0 1 1 2 3 3 3 3 Torus domain zf-CCCH_4 PF18044.1 KFM67188.1 - 4.5e-06 26.3 39.7 7.7e-05 22.4 7.3 4.2 4 1 0 4 4 4 3 CCCH-type zinc finger RWD PF05773.22 KFM67188.1 - 0.005 17.1 1.3 0.016 15.5 0.9 2.1 1 1 0 1 1 1 1 RWD domain NinE PF05322.11 KFM67188.1 - 3.3 7.6 10.3 12 5.9 1.7 3.5 3 0 0 3 3 3 0 NINE Protein RNA_pol_Rpb4 PF03874.16 KFM67189.1 - 1.1e-26 93.6 4.7 1.4e-26 93.3 4.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Sld5 PF05916.11 KFM67190.1 - 4.1e-05 24.0 1.7 8e-05 23.1 1.7 1.5 1 1 0 1 1 1 1 GINS complex protein DED PF01335.21 KFM67190.1 - 0.021 15.1 3.3 0.34 11.3 0.1 2.8 3 0 0 3 3 3 0 Death effector domain SLD5_C PF16922.5 KFM67190.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus Mit_KHE1 PF10173.9 KFM67190.1 - 0.13 12.4 1.1 0.23 11.5 1.1 1.5 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DDE_Tnp_1_7 PF13843.6 KFM67191.1 - 5.2e-06 26.0 0.0 6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 CBM_21 PF03370.13 KFM67193.1 - 6.9e-33 113.2 0.1 1.4e-32 112.2 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFM67193.1 - 6.5e-15 55.5 0.2 2.1e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) DDE_3 PF13358.6 KFM67194.1 - 0.00031 20.5 0.0 0.00062 19.5 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF5137 PF17220.3 KFM67195.1 - 0.085 13.7 0.2 0.12 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5137) AnfO_nitrog PF09582.10 KFM67195.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Branch PF02485.21 KFM67199.1 - 4.6e-14 52.5 0.0 8.2e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme WD40 PF00400.32 KFM67200.1 - 8.7e-26 89.7 12.5 1e-05 26.2 0.2 7.1 6 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM67200.1 - 1.1e-24 86.5 0.3 0.002 18.4 0.0 6.7 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM67200.1 - 1.2e-11 44.9 0.7 1.8e-06 28.0 0.6 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KFM67200.1 - 0.00043 18.4 0.1 0.095 10.7 0.0 2.3 1 1 1 2 2 2 2 IKI3 family WD40_like PF17005.5 KFM67200.1 - 0.0018 17.7 0.0 6.6 6.0 0.0 3.5 2 2 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 KFM67200.1 - 0.0052 15.5 0.9 0.2 10.3 0.2 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.11 KFM67200.1 - 0.0072 15.2 0.1 2.2 7.0 0.0 2.8 2 1 1 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) Peptidase_S9_N PF02897.15 KFM67200.1 - 0.013 14.4 3.2 0.26 10.1 0.2 3.1 2 1 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PD40 PF07676.12 KFM67200.1 - 0.044 13.7 0.0 0.32 11.0 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PP-binding PF00550.25 KFM67201.1 - 3.2e-10 40.2 0.1 4.9e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KFM67201.1 - 0.0024 18.1 0.2 0.0033 17.6 0.2 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.12 KFM67201.1 - 0.14 12.6 0.7 0.29 11.6 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) DDE_3 PF13358.6 KFM67202.1 - 0.00086 19.1 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CUB PF00431.20 KFM67203.1 - 0.0043 17.4 0.1 2.9 8.3 0.0 2.8 2 0 0 2 2 2 2 CUB domain Zip PF02535.22 KFM67203.1 - 0.024 13.9 0.6 0.038 13.2 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Myotoxins PF00819.17 KFM67203.1 - 0.051 13.9 0.7 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 Myotoxin, crotamine Ldl_recept_a PF00057.18 KFM67203.1 - 0.91 9.8 4.8 2.9 8.2 4.8 1.9 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFM67204.1 - 0.00028 21.2 0.0 0.22 11.9 0.1 3.8 4 0 0 4 4 4 1 CUB domain Serinc PF03348.15 KFM67204.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Laminin_N PF00055.17 KFM67205.1 - 8.7e-80 267.7 0.5 8.7e-80 267.7 0.5 1.6 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFM67205.1 - 1.5e-08 34.6 10.0 1.5e-08 34.6 10.0 2.6 2 1 0 2 2 2 1 Laminin EGF domain F5_F8_type_C PF00754.25 KFM67205.1 - 4.5e-05 23.6 0.0 9.7e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 F5/8 type C domain BNR_6 PF15899.5 KFM67205.1 - 0.079 13.1 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 BNR-Asp box repeat SH2 PF00017.24 KFM67206.1 - 5.2e-20 71.3 0.1 1.2e-19 70.1 0.0 1.7 2 0 0 2 2 2 1 SH2 domain DUF1191 PF06697.12 KFM67206.1 - 0.048 13.4 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Y_phosphatase PF00102.27 KFM67207.1 - 7.8e-54 182.7 0.7 9.9e-54 182.4 0.7 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM67207.1 - 4.8e-05 23.2 0.1 0.0001 22.1 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFM67207.1 - 0.0011 19.1 0.5 0.0036 17.4 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFM67207.1 - 0.0053 16.8 0.4 0.03 14.3 0.2 2.1 1 1 2 3 3 3 1 Tyrosine phosphatase family DUF3025 PF11227.8 KFM67208.1 - 0.039 13.8 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) UPF0113 PF03657.13 KFM67209.1 - 1.1e-16 60.8 0.0 1.5e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 KFM67209.1 - 3e-09 37.3 0.3 5.5e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 KFM67209.1 - 7.8e-05 22.6 0.0 9.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 PUA domain DUF885 PF05960.11 KFM67210.1 - 5.7e-21 75.8 0.0 6.3e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Sec23_trunk PF04811.15 KFM67211.1 - 7.1e-70 235.3 0.0 1.1e-69 234.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFM67211.1 - 3.5e-32 111.0 0.1 6.7e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFM67211.1 - 5.9e-28 96.7 0.2 1.6e-27 95.3 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KFM67211.1 - 9.3e-19 67.1 0.0 2.2e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Pkinase PF00069.25 KFM67213.1 - 2.3e-31 109.2 0.1 2.4e-31 109.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM67213.1 - 9.7e-16 57.8 0.1 1.1e-15 57.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KFM67213.1 - 0.00067 19.3 0.1 0.00096 18.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFM67213.1 - 0.038 13.9 0.3 0.051 13.5 0.3 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM67213.1 - 0.096 12.0 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KFM67213.1 - 0.12 11.2 0.2 0.15 10.8 0.2 1.1 1 0 0 1 1 1 0 Fungal protein kinase CDC4_D PF16856.5 KFM67213.1 - 0.47 10.4 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain zf-CCHC PF00098.23 KFM67214.1 - 3.9e-06 26.7 1.2 5.6e-06 26.2 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KFM67214.1 - 0.0011 18.7 1.5 0.0018 18.1 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle HscB_4_cys PF18256.1 KFM67214.1 - 0.065 13.1 1.2 0.14 12.0 1.2 1.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC_4 PF14392.6 KFM67214.1 - 0.069 12.9 0.4 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Exo_endo_phos_2 PF14529.6 KFM67215.1 - 1.2e-07 31.6 0.0 1.4e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM67215.1 - 0.0043 16.6 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Asparaginase_2 PF01112.18 KFM67216.1 - 9.4e-86 287.6 0.1 1.1e-85 287.3 0.1 1.0 1 0 0 1 1 1 1 Asparaginase SBP_bac_3 PF00497.20 KFM67217.1 - 0.00033 20.1 0.0 0.00044 19.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 KFM67217.1 - 0.025 14.4 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel ANF_receptor PF01094.28 KFM67218.1 - 3.8e-53 180.9 0.0 5.3e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFM67218.1 - 1.7e-43 147.4 0.3 4.8e-43 146.0 0.1 1.8 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM67218.1 - 5e-13 49.0 0.0 1.3e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF3437 PF11919.8 KFM67219.1 - 0.033 14.1 4.0 4.1 7.4 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) V-set_CD47 PF08204.11 KFM67220.1 - 0.078 13.0 0.6 0.078 13.0 0.6 2.1 2 1 0 2 2 2 0 CD47 immunoglobulin-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67221.1 - 3.7e-11 43.1 0.1 7e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Transposase DUF19 PF01579.18 KFM67222.1 - 0.055 13.3 13.8 0.077 12.8 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF19) V-set_CD47 PF08204.11 KFM67222.1 - 0.19 11.7 0.3 0.19 11.7 0.3 1.8 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain zf-H2C2_2 PF13465.6 KFM67223.1 - 1.9e-71 233.5 81.4 1.2e-07 31.8 0.3 12.2 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67223.1 - 6.5e-47 155.5 87.3 1.6e-05 25.1 2.1 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67223.1 - 1.9e-34 115.3 85.7 0.0015 19.2 1.4 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM67223.1 - 9e-19 67.2 76.9 0.0033 17.7 1.9 11.8 10 1 1 11 11 11 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM67223.1 - 9.2e-15 54.2 65.6 0.26 11.4 0.2 12.5 11 2 0 11 11 11 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM67223.1 - 4.4e-11 42.8 53.3 0.044 14.1 0.5 11.6 10 2 1 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM67223.1 - 1.3e-10 40.9 56.1 0.078 12.8 0.2 11.2 11 0 0 11 11 11 6 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM67223.1 - 1e-05 25.5 36.2 0.48 10.5 0.0 10.2 4 3 6 10 10 10 3 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM67223.1 - 6e-05 23.1 37.6 9.1 6.5 0.1 10.0 9 1 1 10 10 10 0 DBF zinc finger BolA PF01722.18 KFM67223.1 - 0.00022 21.5 8.7 0.3 11.4 0.1 4.8 2 1 2 5 5 4 1 BolA-like protein ADK_lid PF05191.14 KFM67223.1 - 0.0014 18.6 32.8 2.2 8.3 0.7 7.1 3 2 3 6 6 6 2 Adenylate kinase, active site lid zf-C2H2_9 PF16293.5 KFM67223.1 - 0.0058 16.4 40.8 2 8.3 0.7 9.8 2 2 8 10 10 10 1 C2H2 type zinc-finger (1 copy) zf-CHCC PF10276.9 KFM67223.1 - 0.0062 16.6 20.8 21 5.3 0.0 9.7 11 1 0 11 11 11 0 Zinc-finger domain C1_1 PF00130.22 KFM67223.1 - 0.0089 15.9 58.5 4.6 7.2 0.5 10.4 2 1 9 11 11 11 2 Phorbol esters/diacylglycerol binding domain (C1 domain) TRAF6_Z2 PF18048.1 KFM67223.1 - 0.031 14.4 47.3 0.18 11.9 0.8 10.4 11 0 0 11 11 11 0 TNF receptor-associated factor 6 zinc finger 2 PqqA PF08042.11 KFM67223.1 - 0.061 13.4 7.9 21 5.3 0.4 6.6 8 0 0 8 8 7 0 PqqA family zf-C2HC_2 PF13913.6 KFM67223.1 - 0.066 13.1 38.3 1.2 9.1 0.0 10.1 11 0 0 11 11 11 0 zinc-finger of a C2HC-type DUF3338 PF11819.8 KFM67223.1 - 0.073 13.0 0.3 54 3.8 0.0 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF3338) Sterile PF03015.19 KFM67223.1 - 0.094 13.0 0.5 42 4.4 0.0 4.2 4 2 2 6 6 5 0 Male sterility protein zf-RRPl_C4 PF17026.5 KFM67223.1 - 0.1 12.7 35.3 1.2 9.2 7.1 5.0 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF3396 PF11876.8 KFM67223.1 - 0.11 12.0 0.0 23 4.4 0.0 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF3396) Tox-HNH-HHH PF15637.6 KFM67223.1 - 0.17 12.1 1.2 40 4.4 0.0 3.9 1 1 3 6 6 6 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_2 PF12756.7 KFM67223.1 - 0.19 12.1 68.1 3.3 8.1 1.3 10.2 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KFM67223.1 - 0.29 11.3 51.1 3.8 7.7 7.6 6.2 2 2 4 6 6 6 0 FYVE zinc finger YyzF PF14116.6 KFM67223.1 - 0.31 11.1 35.0 34 4.6 0.1 10.3 11 0 0 11 11 11 0 YyzF-like protein zf_UBZ PF18439.1 KFM67223.1 - 0.44 10.2 45.6 11 5.7 0.9 10.3 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger Cg6151-P PF10233.9 KFM67223.1 - 0.85 10.0 2.4 38 4.6 0.0 4.1 4 2 2 6 6 5 0 Uncharacterized conserved protein CG6151-P DUF2256 PF10013.9 KFM67223.1 - 1.6 8.9 42.9 49 4.1 0.1 10.6 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFM67223.1 - 5.9 7.7 36.8 10 6.9 2.0 5.8 1 1 4 6 6 6 0 zinc-ribbon family SIR2 PF02146.17 KFM67224.1 - 7.4e-23 81.4 0.1 1.3e-14 54.6 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KFM67224.1 - 0.0051 16.6 0.0 0.73 9.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain RQC PF09382.10 KFM67225.1 - 2.1e-24 85.5 0.7 4.2e-24 84.5 0.7 1.5 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 KFM67225.1 - 3.8e-17 62.8 2.2 3.8e-17 62.8 2.2 2.1 2 0 0 2 2 2 1 RecQ zinc-binding Helicase_C PF00271.31 KFM67225.1 - 1.3e-14 54.5 0.0 8.2e-14 51.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 KFM67225.1 - 1e-11 44.6 0.1 2.1e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 HRDC domain DEAD PF00270.29 KFM67225.1 - 0.00019 21.3 0.0 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_Sgs1 PF11408.8 KFM67225.1 - 0.087 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Sgs1 RecQ helicase Vps51 PF08700.11 KFM67225.1 - 0.13 12.3 1.5 0.53 10.4 0.3 2.3 1 1 1 2 2 2 0 Vps51/Vps67 zf-PARP PF00645.18 KFM67226.1 - 0.081 13.8 0.1 0.083 13.8 0.1 1.1 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region RNA_pol_Rpb2_1 PF04563.15 KFM67231.1 - 3.7e-22 78.8 0.0 4e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFM67231.1 - 2.5e-06 27.3 0.0 3.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 DUF3446 PF11928.8 KFM67233.1 - 4 7.8 13.1 1.1 9.7 9.1 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM67234.1 - 2.6e-16 59.6 2.8 5e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67234.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67234.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67234.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67234.1 - 1.8 9.2 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67235.1 - 4.2e-16 59.0 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67235.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67235.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67235.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67235.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Tubulin PF00091.25 KFM67237.1 - 2.8e-67 226.7 0.0 3.9e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM67237.1 - 9.1e-51 171.3 0.0 1.6e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFM67237.1 - 0.00058 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain THAP PF05485.12 KFM67238.1 - 1.3e-23 83.7 18.1 2.5e-14 53.9 5.0 3.4 3 0 0 3 3 3 2 THAP domain Caprin-1_dimer PF18293.1 KFM67239.1 - 9.4e-41 138.9 0.3 9.4e-41 138.9 0.3 1.7 2 1 0 2 2 2 1 Caprin-1 dimerization domain ACOX PF01756.19 KFM67239.1 - 0.014 14.9 0.4 0.024 14.2 0.4 1.5 1 0 0 1 1 1 0 Acyl-CoA oxidase DUF5344 PF17279.2 KFM67239.1 - 0.028 15.0 3.0 0.028 15.0 3.0 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5344) BioT2 PF15368.6 KFM67239.1 - 0.093 12.7 5.3 0.088 12.8 2.7 2.1 2 0 0 2 2 2 0 Spermatogenesis family BioT2 DDE_3 PF13358.6 KFM67241.1 - 1.7e-12 47.3 0.0 6.7e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67241.1 - 6.3e-06 26.4 0.1 1.6e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Transposase PPO1_DWL PF12142.8 KFM67241.1 - 0.069 12.9 0.0 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Polyphenol oxidase middle domain DUF659 PF04937.15 KFM67243.1 - 0.00018 21.4 0.2 0.00066 19.6 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM67243.1 - 0.00031 20.5 0.3 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) COesterase PF00135.28 KFM67244.1 - 2.4e-100 336.9 0.0 2.6e-100 336.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM67244.1 - 0.00013 21.9 1.3 0.00065 19.6 0.5 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold TMIE PF16038.5 KFM67244.1 - 0.27 11.1 3.9 0.57 10.1 3.9 1.4 1 0 0 1 1 1 0 TMIE protein Trypsin PF00089.26 KFM67245.1 - 1.7e-29 103.2 0.0 2.8e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin VWA PF00092.28 KFM67245.1 - 5.6e-29 101.6 0.0 9.1e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Sushi PF00084.20 KFM67245.1 - 7.4e-16 58.5 6.1 6.3e-10 39.5 0.4 2.8 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) VWA_2 PF13519.6 KFM67245.1 - 4.3e-13 49.8 0.0 8.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFM67245.1 - 2.4e-08 34.1 0.0 4.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Redoxin PF08534.10 KFM67245.1 - 0.0052 16.5 0.0 0.042 13.6 0.0 2.3 3 0 0 3 3 3 1 Redoxin DUF1986 PF09342.11 KFM67245.1 - 0.043 14.2 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) ATP1G1_PLM_MAT8 PF02038.16 KFM67245.1 - 1 8.8 4.7 12 5.4 0.1 3.1 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family Alg6_Alg8 PF03155.15 KFM67246.1 - 0.011 14.8 0.1 0.011 14.8 0.1 1.0 1 0 0 1 1 1 0 ALG6, ALG8 glycosyltransferase family Alg6_Alg8 PF03155.15 KFM67247.1 - 1.3e-12 47.4 0.1 1.3e-12 47.4 0.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Alg6_Alg8 PF03155.15 KFM67248.1 - 6.5e-32 111.1 2.0 7.3e-32 111.0 2.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family HLH PF00010.26 KFM67249.1 - 5.4e-15 55.1 0.1 6.6e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Lebercilin PF15619.6 KFM67250.1 - 1.5e-18 67.1 7.6 2.3e-18 66.6 7.7 1.3 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HAP1_N PF04849.13 KFM67250.1 - 0.0017 17.6 4.7 0.0026 17.0 4.7 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region NPV_P10 PF05531.12 KFM67250.1 - 0.0018 18.7 3.0 0.013 15.9 3.0 1.9 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 KFM67250.1 - 0.0025 18.1 3.9 0.0029 17.8 3.9 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SHE3 PF17078.5 KFM67250.1 - 0.0025 17.5 6.9 0.0041 16.9 6.9 1.3 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 SlyX PF04102.12 KFM67250.1 - 0.0039 17.8 3.7 0.063 13.9 2.1 2.6 1 1 1 2 2 2 1 SlyX DUF812 PF05667.11 KFM67250.1 - 0.0068 15.3 3.6 0.011 14.7 3.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF812) WEMBL PF05701.11 KFM67250.1 - 0.009 14.8 5.4 0.01 14.6 5.4 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF4201 PF13870.6 KFM67250.1 - 0.01 15.5 6.2 0.013 15.2 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Bacillus_HBL PF05791.11 KFM67250.1 - 0.011 15.6 3.6 0.013 15.3 3.6 1.0 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.12 KFM67250.1 - 0.013 15.6 0.9 0.016 15.2 0.9 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CALCOCO1 PF07888.11 KFM67250.1 - 0.013 14.4 4.8 0.016 14.1 4.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FPP PF05911.11 KFM67250.1 - 0.015 13.5 6.0 0.018 13.3 6.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DivIC PF04977.15 KFM67250.1 - 0.017 14.9 7.5 0.25 11.1 3.0 2.2 1 1 1 2 2 2 0 Septum formation initiator ADIP PF11559.8 KFM67250.1 - 0.018 15.2 5.5 0.037 14.1 5.5 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KFM67250.1 - 0.022 14.8 9.1 0.11 12.5 9.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 KFM67250.1 - 0.024 14.6 6.6 0.054 13.5 3.8 2.0 1 1 0 2 2 2 0 FlxA-like protein Spc24 PF08286.11 KFM67250.1 - 0.024 14.9 7.1 0.056 13.7 2.1 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FapA PF03961.13 KFM67250.1 - 0.024 13.2 4.2 0.029 13.0 4.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A LURAP PF14854.6 KFM67250.1 - 0.027 14.4 3.8 0.18 11.8 0.7 2.0 1 1 1 2 2 2 0 Leucine rich adaptor protein Sec2p PF06428.11 KFM67250.1 - 0.028 14.4 6.5 0.71 9.9 2.6 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF3450 PF11932.8 KFM67250.1 - 0.03 13.6 3.3 0.044 13.1 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_13 PF13166.6 KFM67250.1 - 0.032 12.9 3.9 0.039 12.6 3.9 1.0 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.11 KFM67250.1 - 0.036 13.9 7.0 0.093 12.5 4.3 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 bZIP_1 PF00170.21 KFM67250.1 - 0.045 13.9 12.0 0.27 11.4 4.2 2.3 1 1 0 2 2 2 0 bZIP transcription factor TMF_TATA_bd PF12325.8 KFM67250.1 - 0.045 14.0 5.1 0.25 11.6 5.1 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Tropomyosin PF00261.20 KFM67250.1 - 0.048 13.0 7.0 0.056 12.8 7.0 1.0 1 0 0 1 1 1 0 Tropomyosin DUF4140 PF13600.6 KFM67250.1 - 0.053 14.0 3.0 0.3 11.5 0.5 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF5320 PF17253.2 KFM67250.1 - 0.067 14.3 4.3 5.6 8.1 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Lzipper-MIP1 PF14389.6 KFM67250.1 - 0.073 13.4 5.8 0.28 11.5 5.8 1.9 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Csm1_N PF18504.1 KFM67250.1 - 0.079 13.3 8.7 0.84 10.0 1.1 2.9 1 1 2 3 3 3 0 Csm1 N-terminal domain Tup_N PF08581.10 KFM67250.1 - 0.083 13.2 4.9 0.27 11.5 4.8 1.8 1 1 0 1 1 1 0 Tup N-terminal DUF5082 PF16888.5 KFM67250.1 - 0.086 13.1 3.4 0.22 11.8 3.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) FlaC_arch PF05377.11 KFM67250.1 - 0.088 13.2 4.9 2.2 8.7 0.5 2.4 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) FAM76 PF16046.5 KFM67250.1 - 0.088 12.1 5.8 0.11 11.8 5.8 1.0 1 0 0 1 1 1 0 FAM76 protein USP8_interact PF08941.10 KFM67250.1 - 0.093 12.5 1.9 0.45 10.3 0.1 1.9 1 1 1 2 2 2 0 USP8 interacting GAS PF13851.6 KFM67250.1 - 0.11 11.9 8.9 0.18 11.1 8.9 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KFM67250.1 - 0.13 11.1 6.4 0.16 10.8 6.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Spc34 PF08657.10 KFM67250.1 - 0.14 12.0 3.7 0.16 11.7 3.7 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 TSC22 PF01166.18 KFM67250.1 - 0.15 12.4 8.2 1.6 9.1 1.6 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family V_ATPase_I PF01496.19 KFM67250.1 - 0.17 9.8 2.4 0.18 9.7 2.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rbsn PF11464.8 KFM67250.1 - 0.18 11.6 0.4 0.18 11.6 0.4 2.3 2 0 0 2 2 2 0 Rabenosyn Rab binding domain DUF5595 PF18077.1 KFM67250.1 - 0.21 11.7 6.0 2.9 8.1 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) DUF1664 PF07889.12 KFM67250.1 - 0.21 11.6 2.8 0.29 11.2 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Med9 PF07544.13 KFM67250.1 - 0.22 11.6 5.9 1.3 9.1 2.7 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CLZ PF16526.5 KFM67250.1 - 0.26 11.7 7.2 4.7 7.6 0.4 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_2 PF07716.15 KFM67250.1 - 0.34 11.0 8.2 2.1 8.5 2.6 2.5 2 1 0 2 2 2 0 Basic region leucine zipper UPF0242 PF06785.11 KFM67250.1 - 0.39 10.8 7.3 0.6 10.2 7.3 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 KFM67250.1 - 0.43 11.2 5.9 2.7 8.7 5.9 1.9 1 1 0 1 1 1 0 Initiation control protein YabA Prefoldin_2 PF01920.20 KFM67250.1 - 0.63 10.0 10.8 1.2 9.2 1.1 2.5 1 1 0 2 2 2 0 Prefoldin subunit Swi5 PF07061.11 KFM67250.1 - 0.67 10.1 6.6 2.7 8.2 2.0 2.1 1 1 1 2 2 2 0 Swi5 APG6_N PF17675.1 KFM67250.1 - 0.85 10.1 8.5 2.9 8.4 8.5 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4988 PF16378.5 KFM67250.1 - 1.1 8.9 4.2 4.4 6.9 0.6 2.0 1 1 0 2 2 2 0 Domain of unknown function XkdW PF09636.10 KFM67250.1 - 6.1 7.0 7.1 3.3 7.9 0.5 2.3 1 1 1 2 2 2 0 XkdW protein Herpes_UL52 PF03121.15 KFM67251.1 - 0.71 9.9 2.8 1.7 8.7 0.3 2.2 1 1 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase SH3BGR PF04908.15 KFM67252.1 - 9.4e-16 57.8 0.6 1.3e-15 57.3 0.6 1.2 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein SAM_2 PF07647.17 KFM67254.1 - 1.6e-15 57.0 0.1 2.7e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM67254.1 - 9.4e-10 38.8 0.2 1.5e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) betaPIX_CC PF16523.5 KFM67254.1 - 0.086 12.7 6.1 0.16 11.8 6.1 1.4 1 0 0 1 1 1 0 betaPIX coiled coil Spc7 PF08317.11 KFM67255.1 - 0.00028 19.9 9.0 0.00043 19.3 9.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Fez1 PF06818.15 KFM67255.1 - 0.00069 20.1 7.2 0.00069 20.1 7.2 1.7 2 0 0 2 2 2 1 Fez1 MPS2 PF17060.5 KFM67255.1 - 0.0012 18.2 3.0 0.0018 17.6 3.0 1.2 1 0 0 1 1 1 1 Monopolar spindle protein 2 TACC_C PF05010.14 KFM67255.1 - 0.0034 17.2 9.8 0.0052 16.6 9.8 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal MAD PF05557.13 KFM67255.1 - 0.016 13.6 12.7 0.022 13.2 12.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein FapA PF03961.13 KFM67255.1 - 0.029 13.0 4.9 0.037 12.7 4.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 KFM67255.1 - 0.039 14.2 11.4 0.087 13.1 11.4 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HMMR_N PF15905.5 KFM67255.1 - 0.11 11.9 16.5 0.15 11.5 16.5 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Exonuc_VII_L PF02601.15 KFM67255.1 - 0.15 11.6 2.0 0.2 11.2 2.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1204 PF06721.11 KFM67255.1 - 0.16 11.4 4.5 0.28 10.6 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) T3SSipB PF16535.5 KFM67255.1 - 0.19 12.2 6.2 0.067 13.7 3.5 1.6 2 0 0 2 2 2 0 Type III cell invasion protein SipB OmpH PF03938.14 KFM67255.1 - 0.38 11.1 11.1 0.8 10.0 11.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Prominin PF05478.11 KFM67255.1 - 0.4 8.6 6.2 0.53 8.2 6.2 1.1 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 KFM67255.1 - 0.42 10.7 14.0 0.36 10.9 12.2 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 KFM67255.1 - 0.51 10.7 7.7 1.9 8.8 0.5 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein Ribosomal_L30_N PF08079.12 KFM67255.1 - 0.58 10.5 11.9 0.091 13.0 7.2 2.2 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain PrmA PF06325.13 KFM67255.1 - 0.69 9.2 3.3 1 8.7 3.3 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DivIC PF04977.15 KFM67255.1 - 1.1 9.1 13.4 2.3 8.1 4.9 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF745 PF05335.13 KFM67255.1 - 4.1 7.1 12.8 1.9 8.2 8.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) BRE1 PF08647.11 KFM67255.1 - 5.7 7.1 15.5 0.21 11.7 6.0 2.7 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase PDZ_5 PF17817.1 KFM67256.1 - 4.6e-35 119.7 2.3 9.9e-35 118.7 2.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM67256.1 - 6.3e-12 45.7 1.5 1.2e-11 44.8 1.5 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM67256.1 - 3.5e-07 30.0 0.2 8.6e-07 28.7 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM67256.1 - 0.0021 18.4 1.1 0.0054 17.0 1.1 1.7 1 0 0 1 1 1 1 PDZ domain FliE PF02049.18 KFM67257.1 - 0.075 13.2 1.0 0.58 10.3 0.5 2.1 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE DUF4995 PF16386.5 KFM67257.1 - 0.14 12.1 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function Cyto_heme_lyase PF01265.17 KFM67258.1 - 0.2 11.2 9.5 0.16 11.5 2.0 2.2 1 1 1 2 2 2 0 Cytochrome c/c1 heme lyase JmjC PF02373.22 KFM67259.1 - 1.7e-20 73.6 1.0 1e-19 71.0 1.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KFM67259.1 - 2.9e-14 53.4 4.3 1.1e-13 51.5 4.3 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFM67259.1 - 0.053 13.0 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein AAA PF00004.29 KFM67260.1 - 2.6e-53 180.0 0.0 9.7e-40 136.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM67260.1 - 4.3e-12 45.6 0.7 2.5e-11 43.2 0.3 2.6 2 0 0 2 2 2 1 AAA+ lid domain CDC48_N PF02359.18 KFM67260.1 - 9e-11 41.8 0.0 1e-09 38.4 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.6 KFM67260.1 - 3e-07 30.8 0.1 0.0082 16.4 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KFM67260.1 - 7.1e-07 29.8 0.0 0.012 16.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 KFM67260.1 - 7.9e-07 28.9 0.0 0.012 15.4 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 KFM67260.1 - 8.3e-07 28.7 0.1 1.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.13 KFM67260.1 - 8.7e-07 28.5 0.0 0.056 12.6 0.0 2.9 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_2 PF07724.14 KFM67260.1 - 1.1e-06 28.9 0.0 8.7e-05 22.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFM67260.1 - 3.6e-06 27.0 0.1 0.0014 18.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFM67260.1 - 4.5e-06 26.7 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KFM67260.1 - 4.9e-06 26.1 0.2 0.0066 15.8 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFM67260.1 - 8.3e-06 26.4 0.0 0.11 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KFM67260.1 - 1e-05 25.3 0.0 0.06 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KFM67260.1 - 4.8e-05 23.3 0.0 1.5 8.7 0.0 3.9 3 1 1 4 4 4 1 NACHT domain ATPase PF06745.13 KFM67260.1 - 5.1e-05 22.7 0.0 0.0024 17.3 0.0 2.7 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.22 KFM67260.1 - 5.2e-05 23.6 0.0 0.051 14.0 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 KFM67260.1 - 5.6e-05 23.3 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KFM67260.1 - 0.0002 21.3 0.3 8.3 6.2 0.1 4.2 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KFM67260.1 - 0.00065 19.7 0.0 0.073 13.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KFM67260.1 - 0.00068 19.2 0.0 0.032 13.8 0.0 2.9 2 1 1 3 3 3 1 P-loop containing dynein motor region AAA_25 PF13481.6 KFM67260.1 - 0.0009 18.9 0.4 1.6 8.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.11 KFM67260.1 - 0.0011 18.8 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KFM67260.1 - 0.0011 18.7 0.0 0.076 12.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.6 KFM67260.1 - 0.0065 16.3 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KFM67260.1 - 0.0086 15.2 0.0 0.51 9.4 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 KTI12 PF08433.10 KFM67260.1 - 0.011 15.2 0.0 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 KFM67260.1 - 0.017 15.4 0.0 5.2 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KFM67260.1 - 0.019 14.6 0.0 0.52 10.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 KFM67260.1 - 0.022 14.2 0.0 17 4.7 0.1 3.3 2 1 0 2 2 2 0 Bacterial TniB protein ATP_bind_1 PF03029.17 KFM67260.1 - 0.027 14.3 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KFM67260.1 - 0.032 13.9 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFM67260.1 - 0.046 13.0 0.5 12 5.1 0.1 3.5 3 1 0 3 3 2 0 Zeta toxin PhoH PF02562.16 KFM67260.1 - 0.052 13.0 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.6 KFM67260.1 - 0.062 13.7 0.0 16 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KFM67260.1 - 0.083 12.3 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 KFM67260.1 - 0.14 12.5 0.0 1.5 9.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM67260.1 - 0.16 12.5 0.5 0.41 11.1 0.0 1.9 3 0 0 3 3 1 0 ABC transporter CRAL_TRIO_2 PF13716.6 KFM67261.1 - 4.3e-11 43.1 0.0 6.5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM67261.1 - 9e-10 38.5 0.0 2.3e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain Spectrin PF00435.21 KFM67261.1 - 2.6e-07 31.1 3.9 0.00047 20.6 0.1 3.4 3 0 0 3 3 3 2 Spectrin repeat CortBP2 PF09727.9 KFM67262.1 - 0.025 14.5 0.2 0.026 14.4 0.2 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 RhoGEF PF00621.20 KFM67263.1 - 1.2e-67 227.7 29.0 9.6e-36 123.7 1.1 4.6 3 1 0 3 3 3 2 RhoGEF domain Spectrin PF00435.21 KFM67263.1 - 1.2e-28 99.7 57.0 4.7e-14 52.7 1.0 6.4 6 1 0 6 6 6 4 Spectrin repeat PH PF00169.29 KFM67263.1 - 2.2e-11 44.2 7.1 4.1e-05 24.0 0.1 3.7 4 0 0 4 4 4 2 PH domain PH_10 PF15411.6 KFM67263.1 - 1.6e-09 38.1 5.6 0.00049 20.3 0.5 4.3 2 2 0 2 2 2 2 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFM67263.1 - 1.9e-06 27.9 4.0 0.023 14.6 0.1 4.1 3 0 0 3 3 3 2 PH domain SH3-RhoG_link PF16609.5 KFM67263.1 - 0.00014 21.7 9.9 0.012 15.3 9.3 2.9 1 1 0 1 1 1 1 SH3-RhoGEF linking unstructured region PH_9 PF15410.6 KFM67263.1 - 0.006 16.9 1.4 3.9 7.9 0.0 3.5 3 0 0 3 3 3 2 Pleckstrin homology domain Metal_resist PF13801.6 KFM67263.1 - 0.03 14.5 0.6 0.03 14.5 0.6 2.5 2 0 0 2 2 2 0 Heavy-metal resistance Gal-bind_lectin PF00337.22 KFM67265.1 - 8e-90 297.3 0.0 2.6e-33 114.4 0.0 3.0 3 0 0 3 3 3 3 Galactoside-binding lectin WIF PF02019.18 KFM67265.1 - 0.023 14.4 0.0 7.7 6.2 0.0 2.4 2 0 0 2 2 2 0 WIF domain Vps26 PF03643.15 KFM67266.1 - 2.1e-133 443.5 5.4 2.4e-133 443.3 5.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 KFM67266.1 - 9.4e-05 22.9 0.5 0.053 14.0 0.2 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFM67266.1 - 0.00037 20.6 0.6 0.044 13.8 0.0 3.1 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arm PF00514.23 KFM67267.1 - 4.1e-35 118.7 11.0 4.6e-08 32.8 0.0 6.8 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFM67267.1 - 3.5e-08 33.7 0.3 0.00011 22.5 0.0 3.3 2 2 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KFM67267.1 - 6.6e-06 26.5 2.2 1.6 9.3 0.0 5.2 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 KFM67267.1 - 0.00044 20.3 5.2 1.9 8.9 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Atx10homo_assoc PF09759.9 KFM67267.1 - 0.00079 19.4 0.3 0.012 15.7 0.1 2.7 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.20 KFM67267.1 - 0.042 12.4 0.0 0.41 9.1 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 KFM67267.1 - 0.13 12.3 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 PrkA PF06798.12 KFM67268.1 - 0.12 12.0 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain CRAL_TRIO PF00650.20 KFM67270.1 - 1.9e-27 96.0 0.0 2.8e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM67270.1 - 4.9e-06 26.7 0.0 8.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM67270.1 - 2.7e-05 24.3 0.6 7e-05 22.9 0.6 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SCP-1 PF05483.12 KFM67270.1 - 0.029 12.4 1.2 0.037 12.1 1.2 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) DDE_3 PF13358.6 KFM67271.1 - 0.05 13.4 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DRIM PF07539.12 KFM67271.1 - 0.19 10.0 0.0 0.19 10.0 0.0 1.0 1 0 0 1 1 1 0 Down-regulated in metastasis CRAL_TRIO PF00650.20 KFM67274.1 - 8.4e-25 87.3 0.1 1.2e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM67274.1 - 0.0038 17.4 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM67275.1 - 1.7e-29 102.6 0.2 2.2e-29 102.2 0.2 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM67275.1 - 3.8e-06 27.1 0.0 5.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain KH_dom-like PF14714.6 KFM67277.1 - 0.0024 18.1 0.3 0.0024 18.1 0.3 1.1 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal HLH PF00010.26 KFM67279.1 - 2.9e-15 56.0 1.1 8.2e-15 54.5 1.1 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Activator_LAG-3 PF11498.8 KFM67279.1 - 6.3 5.6 11.2 0.058 12.4 2.7 1.9 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Ig_3 PF13927.6 KFM67280.1 - 1.4e-13 51.2 0.2 3.9e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain fn3 PF00041.21 KFM67280.1 - 1.2e-10 41.6 0.6 2.3e-10 40.7 0.6 1.5 1 0 0 1 1 1 1 Fibronectin type III domain I-set PF07679.16 KFM67280.1 - 1.7e-10 40.8 0.0 7e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFM67280.1 - 1.8e-08 34.5 0.0 5.1e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM67280.1 - 7e-06 26.3 0.0 1.5e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Tissue_fac PF01108.17 KFM67280.1 - 7.9e-05 22.5 0.2 0.00014 21.7 0.2 1.4 1 0 0 1 1 1 1 Tissue factor Pur_ac_phosph_N PF16656.5 KFM67280.1 - 0.00095 19.7 0.4 0.0035 17.9 0.4 2.0 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFM67280.1 - 0.032 14.4 0.2 0.68 10.1 0.0 2.8 2 2 1 3 3 3 0 Immunoglobulin V-set domain DUF5581 PF17744.1 KFM67280.1 - 0.21 10.9 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5581) RA PF00788.23 KFM67282.1 - 1.7e-09 38.2 0.0 5.4e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PTPlike_phytase PF14566.6 KFM67282.1 - 1.4 9.0 16.8 0.87 9.7 8.0 3.1 3 0 0 3 3 3 0 Inositol hexakisphosphate zf-RING_2 PF13639.6 KFM67283.1 - 1.2e-12 47.9 7.7 3e-12 46.7 7.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM67283.1 - 5.1e-08 32.6 7.2 1e-07 31.7 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM67283.1 - 7.8e-08 31.9 3.7 1.7e-07 30.9 3.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KFM67283.1 - 1.1e-07 32.0 4.7 2.8e-07 30.7 4.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM67283.1 - 4.4e-07 29.7 6.3 9e-07 28.7 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM67283.1 - 1.8e-05 24.6 4.0 3.9e-05 23.5 4.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM67283.1 - 0.0018 18.1 3.5 0.0035 17.2 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFM67283.1 - 0.0028 17.6 1.7 0.0059 16.6 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KFM67283.1 - 0.0082 16.1 6.3 0.02 14.9 6.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM67283.1 - 0.11 12.4 5.5 0.29 11.0 5.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KFM67283.1 - 0.26 10.9 3.2 0.56 9.9 3.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HNOB PF07700.15 KFM67284.1 - 4.9e-33 114.4 0.2 7.8e-33 113.7 0.2 1.3 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 KFM67284.1 - 0.31 10.4 2.7 0.2 11.1 0.9 1.6 2 0 0 2 2 2 0 Heme NO binding associated 2-oxoacid_dh PF00198.23 KFM67287.1 - 6.4e-84 281.0 0.0 9e-84 280.6 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFM67287.1 - 1.1e-17 63.6 0.0 2.9e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFM67287.1 - 8.2e-14 51.7 0.0 1.8e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFM67287.1 - 0.0053 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like DUF4371 PF14291.6 KFM67288.1 - 2.6e-10 40.3 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) PepX_C PF08530.10 KFM67288.1 - 0.14 12.0 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain IMPDH PF00478.25 KFM67289.1 - 1.6e-138 461.4 3.8 1.9e-138 461.2 3.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KFM67289.1 - 2.9e-11 43.7 0.3 0.00039 20.8 0.2 3.3 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 KFM67289.1 - 7.6e-11 42.0 2.1 1.6e-06 27.8 0.7 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KFM67289.1 - 4.2e-09 35.9 0.7 6.4e-09 35.3 0.7 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KFM67289.1 - 8.8e-06 25.3 2.4 0.0011 18.4 0.2 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein NanE PF04131.14 KFM67289.1 - 0.00079 18.7 0.3 0.0019 17.4 0.3 1.6 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 KFM67289.1 - 0.0011 18.3 0.6 0.0021 17.4 0.6 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KFM67289.1 - 0.0031 16.7 2.4 0.006 15.8 2.4 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase YpsA PF06908.11 KFM67289.1 - 0.025 14.6 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 YspA SLOG family B12-binding PF02310.19 KFM67289.1 - 0.035 14.2 0.1 0.075 13.1 0.1 1.5 1 0 0 1 1 1 0 B12 binding domain BATS PF06968.13 KFM67289.1 - 0.14 12.3 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Biotin and Thiamin Synthesis associated domain DHO_dh PF01180.21 KFM67289.1 - 0.14 11.3 2.1 0.11 11.7 0.2 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Dus PF01207.17 KFM67289.1 - 0.16 11.1 0.8 1.1 8.3 0.1 2.1 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF561 PF04481.12 KFM67289.1 - 0.2 10.8 1.8 0.19 10.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF561) HRM PF02793.22 KFM67290.1 - 1.8e-08 34.5 1.4 2.6e-07 30.8 0.6 2.5 2 0 0 2 2 2 1 Hormone receptor domain GPS PF01825.21 KFM67290.1 - 0.00018 22.0 0.8 0.00047 20.6 0.8 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LapA_dom PF06305.11 KFM67290.1 - 0.16 11.8 0.5 0.41 10.5 0.5 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain 7tm_2 PF00002.24 KFM67291.1 - 8.2e-05 22.0 0.6 0.0001 21.7 0.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) PEN-2 PF10251.9 KFM67291.1 - 0.027 14.9 0.3 0.032 14.6 0.3 1.2 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Bromodomain PF00439.25 KFM67293.1 - 1.6e-18 66.5 0.2 3.9e-18 65.3 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Endonuc_Holl PF10107.9 KFM67293.1 - 0.0013 18.6 3.2 0.0033 17.3 0.3 3.1 2 0 0 2 2 2 1 Endonuclease related to archaeal Holliday junction resolvase Cullin PF00888.22 KFM67294.1 - 3.4e-166 554.5 21.7 5.3e-166 553.8 21.7 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFM67294.1 - 9.7e-23 80.0 7.0 1.9e-22 79.1 5.4 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain Hemopexin PF00045.19 KFM67295.1 - 2.5e-44 149.0 20.2 5.5e-14 51.8 1.9 4.5 4 0 0 4 4 4 4 Hemopexin Peptidase_M10 PF00413.24 KFM67295.1 - 4e-42 143.7 0.0 6.4e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 KFM67295.1 - 3.1e-09 36.9 0.7 5.4e-09 36.1 0.1 1.7 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_4 PF13583.6 KFM67295.1 - 0.00041 20.0 0.2 0.00079 19.1 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KFM67295.1 - 0.0042 17.6 0.0 0.0085 16.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFM67295.1 - 0.0075 15.9 0.0 0.41 10.2 0.0 2.2 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) DUF4953 PF16313.5 KFM67295.1 - 0.0095 15.2 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Met-zincin Reprolysin_5 PF13688.6 KFM67295.1 - 0.04 14.1 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KFM67295.1 - 0.048 12.6 0.5 0.086 11.8 0.5 1.3 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 KFM67295.1 - 0.086 11.4 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase family Rad1 PF02144.16 KFM67296.1 - 4.8e-10 38.9 0.1 5.4e-10 38.8 0.1 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Clathrin_propel PF01394.20 KFM67297.1 - 2.9e-13 49.4 2.8 0.0004 20.6 0.2 5.8 6 0 0 6 6 6 5 Clathrin propeller repeat SH3_1 PF00018.28 KFM67300.1 - 8.3e-49 163.0 3.6 3.5e-16 58.5 0.2 3.4 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 KFM67300.1 - 4.6e-44 148.0 4.2 7.5e-16 57.7 0.2 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KFM67300.1 - 9.6e-31 105.3 1.4 4.5e-11 42.3 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.24 KFM67300.1 - 2.7e-21 75.4 0.1 6.1e-21 74.3 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 KFM67300.1 - 1.3e-08 35.0 3.9 0.0016 18.7 0.1 3.6 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_10 PF17902.1 KFM67300.1 - 2.1e-08 34.1 0.6 0.0003 20.8 0.0 3.4 3 0 0 3 3 3 2 SH3 domain hSH3 PF14603.6 KFM67300.1 - 0.00015 22.1 0.1 0.17 12.3 0.1 2.7 2 0 0 2 2 2 2 Helically-extended SH3 domain SH3_16 PF18348.1 KFM67300.1 - 0.0034 17.1 0.2 2.9 7.8 0.1 3.4 3 0 0 3 3 3 1 Bacterial dipeptidyl-peptidase Sh3 domain Myosin_tail_1 PF01576.19 KFM67302.1 - 2.6e-80 270.6 166.2 3.2e-80 270.3 166.2 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 KFM67302.1 - 4.8e-10 39.5 125.4 4e-07 29.9 38.0 7.4 1 1 5 6 6 6 3 Intermediate filament protein DUF3584 PF12128.8 KFM67302.1 - 4.8e-05 21.1 48.8 4.8e-05 21.1 48.8 4.2 1 1 2 3 3 2 1 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 KFM67302.1 - 0.00058 19.9 11.5 0.00058 19.9 11.5 9.5 1 1 8 9 9 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KFM67302.1 - 0.0039 17.4 9.6 0.0039 17.4 9.6 11.8 2 2 9 11 11 9 3 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 KFM67302.1 - 0.0059 17.2 2.9 0.0059 17.2 2.9 14.1 2 2 11 14 14 12 2 SlyX TMF_DNA_bd PF12329.8 KFM67302.1 - 0.013 15.5 10.7 0.013 15.5 10.7 14.1 3 3 8 12 12 10 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 KFM67302.1 - 0.02 14.9 113.3 0.17 12.0 4.0 10.3 4 4 6 10 10 10 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KFM67302.1 - 1.5 9.0 171.0 0.45 10.7 21.1 9.4 1 1 8 9 9 9 0 Autophagy protein 16 (ATG16) EspB_PE PF18625.1 KFM67302.1 - 6.2 7.4 12.2 3.2 8.3 0.5 4.1 3 1 0 3 3 3 0 ESX-1 secreted protein B PE domain T7SS_ESX_EspC PF10824.8 KFM67302.1 - 7.5 7.1 24.0 2.2 8.8 0.5 7.6 5 4 3 8 8 8 0 Excreted virulence factor EspC, type VII ESX diderm SIX1_SD PF16878.5 KFM67303.1 - 0.064 13.8 0.4 0.064 13.8 0.4 1.6 2 0 0 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain Efg1 PF10153.9 KFM67303.1 - 0.11 12.8 5.5 0.095 13.1 2.3 2.1 2 0 0 2 2 2 0 rRNA-processing protein Efg1 FH2 PF02181.23 KFM67304.1 - 3.8e-63 213.9 6.7 6.4e-63 213.1 6.7 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain TusA PF01206.17 KFM67304.1 - 0.088 12.7 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 Sulfurtransferase TusA LMBR1 PF04791.16 KFM67304.1 - 1.9 7.3 5.4 28 3.4 3.3 2.8 3 0 0 3 3 3 0 LMBR1-like membrane protein Formin_GBD_N PF18382.1 KFM67305.1 - 5.4e-39 132.6 0.1 5.9e-39 132.5 0.1 1.0 1 0 0 1 1 1 1 Formin N-terminal GTPase-binding domain Nicastrin PF05450.15 KFM67306.1 - 0.48 9.9 2.9 0.59 9.6 0.0 2.4 2 1 1 3 3 3 0 Nicastrin DUF1731 PF08338.11 KFM67311.1 - 2.1e-18 65.9 0.0 6.3e-18 64.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 KFM67311.1 - 2e-08 34.0 0.0 6.8e-06 25.7 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 KFM67311.1 - 0.012 15.5 0.1 0.11 12.5 0.1 2.1 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KFM67311.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KFM67311.1 - 0.032 13.7 0.1 0.16 11.4 0.1 1.9 1 1 1 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.6 KFM67311.1 - 0.041 13.8 0.1 0.091 12.6 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding ApbA PF02558.16 KFM67311.1 - 0.085 12.5 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KFM67311.1 - 0.086 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 KFM67311.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 KFM67311.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain zf-MYST PF17772.1 KFM67313.1 - 0.0054 16.3 1.4 0.0069 16.0 1.4 1.2 1 0 0 1 1 1 1 MYST family zinc finger domain zf-U1 PF06220.12 KFM67313.1 - 0.061 13.1 2.6 0.12 12.2 2.6 1.5 1 0 0 1 1 1 0 U1 zinc finger Pox_VLTF3 PF04947.14 KFM67313.1 - 0.061 13.0 0.2 0.062 13.0 0.2 1.0 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like zf-C2H2_8 PF15909.5 KFM67313.1 - 0.064 13.6 0.5 0.069 13.5 0.5 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 KFM67315.1 - 1e-29 101.3 70.7 2.1e-05 24.7 0.4 10.6 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM67315.1 - 5.7e-22 77.1 63.8 2.6e-05 24.4 1.4 10.2 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM67315.1 - 2.5e-19 68.3 70.2 0.054 14.4 0.5 10.9 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFM67315.1 - 6.1e-07 29.7 27.7 0.0016 18.7 4.7 5.8 1 1 5 6 6 6 4 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KFM67315.1 - 1.3e-05 25.4 37.2 0.0051 17.0 0.9 6.3 4 2 1 6 6 6 3 Aberrant zinc-finger zf-met PF12874.7 KFM67315.1 - 6 7.4 30.5 1.4 9.4 4.3 7.1 7 0 0 7 7 7 0 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.6 KFM67316.1 - 0.11 13.1 3.6 0.27 11.8 3.6 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain APG6 PF04111.12 KFM67317.1 - 9e-73 244.0 0.1 1.6e-72 243.2 0.1 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KFM67317.1 - 4.5e-28 98.4 31.1 4.5e-28 98.4 31.1 1.9 2 0 0 2 2 2 1 Apg6 coiled-coil region YabA PF06156.13 KFM67317.1 - 0.016 15.8 9.0 0.026 15.1 7.6 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 KFM67317.1 - 0.046 12.6 13.4 0.081 11.8 13.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Hat1_N PF10394.9 KFM67317.1 - 0.068 13.4 1.5 0.18 12.0 0.1 2.2 2 0 0 2 2 2 0 Histone acetyl transferase HAT1 N-terminus V_ATPase_I PF01496.19 KFM67317.1 - 0.085 10.8 5.6 0.12 10.3 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BH3 PF15285.6 KFM67317.1 - 0.098 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Macoilin PF09726.9 KFM67317.1 - 0.13 10.8 8.4 0.2 10.1 8.4 1.3 1 0 0 1 1 1 0 Macoilin family Neur_chan_memb PF02932.16 KFM67317.1 - 0.27 11.3 2.4 0.41 10.7 2.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FapA PF03961.13 KFM67317.1 - 0.31 9.6 6.4 0.54 8.8 6.4 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KFM67317.1 - 0.92 9.0 4.5 1.5 8.3 4.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nsp1_C PF05064.13 KFM67317.1 - 0.95 9.3 22.2 0.13 12.1 8.5 3.4 1 1 2 3 3 3 0 Nsp1-like C-terminal region YscO PF07321.12 KFM67317.1 - 1.1 9.1 18.3 1.5 8.8 16.7 2.0 1 1 0 1 1 1 0 Type III secretion protein YscO Cys_rich_CPXG PF14255.6 KFM67317.1 - 1.2 9.1 5.0 1.1 9.2 0.2 2.8 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-C2H2 PF00096.26 KFM67318.1 - 1.1e-12 47.6 11.2 9.3e-07 29.0 1.8 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67318.1 - 2.5e-09 37.2 9.5 0.00021 21.9 1.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM67318.1 - 2.2e-05 24.3 9.0 0.00041 20.3 1.0 2.3 1 1 1 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM67318.1 - 6.9e-05 23.0 4.8 0.0038 17.5 0.5 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 KFM67318.1 - 0.00011 22.4 1.7 0.00013 22.1 1.7 1.2 1 0 0 1 1 1 1 TFIIH C1-like domain zf-met PF12874.7 KFM67318.1 - 0.00015 22.0 8.2 0.0034 17.7 1.7 2.7 2 1 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_3 PF13878.6 KFM67318.1 - 0.00071 19.3 0.2 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO LIM PF00412.22 KFM67318.1 - 0.00076 19.7 6.1 0.1 12.9 0.9 2.2 1 1 1 2 2 2 2 LIM domain zf_UBZ PF18439.1 KFM67318.1 - 0.0048 16.5 1.5 0.3 10.7 0.2 2.4 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KFM67318.1 - 0.0056 17.1 13.3 0.013 15.9 0.9 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.12 KFM67318.1 - 0.0082 16.4 4.5 0.012 15.9 0.9 2.0 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-LYAR PF08790.11 KFM67318.1 - 0.015 15.2 4.7 0.13 12.2 1.0 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_4 PF13717.6 KFM67318.1 - 0.035 14.0 4.2 1.9 8.5 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 KFM67318.1 - 0.047 13.7 2.2 0.13 12.4 0.2 2.0 1 1 1 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.10 KFM67318.1 - 0.049 13.8 3.4 0.8 9.9 3.4 2.1 1 1 0 1 1 1 0 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 KFM67318.1 - 0.053 13.2 7.3 0.94 9.2 0.7 2.2 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_ZIC PF18366.1 KFM67318.1 - 0.067 13.3 0.9 0.067 13.3 0.9 2.2 1 1 1 2 2 2 0 Zic proteins zinc finger domain FYVE PF01363.21 KFM67318.1 - 0.13 12.4 8.1 0.23 11.6 8.1 1.4 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFM67318.1 - 0.16 12.4 7.1 3.2 8.2 0.4 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 KFM67318.1 - 0.19 10.2 6.5 0.039 12.5 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_11 PF16622.5 KFM67318.1 - 0.29 10.9 6.3 6.3 6.7 1.6 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KFM67318.1 - 0.49 10.9 9.5 1.2 9.6 1.5 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger RIG-I_C-RD PF11648.8 KFM67318.1 - 0.55 10.5 4.9 1.5 9.1 0.6 2.0 1 1 1 2 2 2 0 C-terminal domain of RIG-I zf-AN1 PF01428.16 KFM67318.1 - 1.6 8.9 9.3 1.4 9.1 0.2 2.4 3 0 0 3 3 2 0 AN1-like Zinc finger Lipase PF00151.19 KFM67319.1 - 0.00051 19.5 0.0 0.00066 19.1 0.0 1.1 1 0 0 1 1 1 1 Lipase Glucodextran_C PF09985.9 KFM67320.1 - 0.034 13.6 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 C-terminal binding-module, SLH-like, of glucodextranase Lipase PF00151.19 KFM67321.1 - 0.06 12.6 0.1 0.092 12.0 0.0 1.3 2 0 0 2 2 2 0 Lipase p450 PF00067.22 KFM67322.1 - 7.1e-113 377.8 0.1 8.3e-113 377.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 YqbF PF14553.6 KFM67322.1 - 0.14 12.0 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 YqbF, hypothetical protein domain p450 PF00067.22 KFM67323.1 - 9.7e-85 285.0 0.0 1.2e-84 284.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Endonuclease_NS PF01223.23 KFM67324.1 - 8.2e-65 218.8 0.4 9.5e-65 218.6 0.5 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 KFM67324.1 - 0.14 12.3 0.4 0.56 10.3 0.4 2.0 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease p450 PF00067.22 KFM67325.1 - 5.4e-108 361.7 0.0 6.2e-108 361.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tri3 PF07428.11 KFM67325.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 DNase_II PF03265.15 KFM67326.1 - 4.3e-92 308.8 2.3 4.9e-92 308.7 2.3 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II Methyltrn_RNA_3 PF02598.17 KFM67328.1 - 1.7e-103 346.1 0.0 2.7e-103 345.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 KFM67328.1 - 0.004 17.3 0.0 0.87 9.8 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family POPLD PF08170.12 KFM67328.1 - 0.027 14.8 0.4 0.056 13.8 0.4 1.5 1 0 0 1 1 1 0 POPLD (NUC188) domain SR-25 PF10500.9 KFM67328.1 - 0.58 9.7 9.9 0.92 9.1 9.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BK_channel_a PF03493.18 KFM67332.1 - 2e-29 101.7 0.0 5e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 KFM67332.1 - 0.017 15.4 0.0 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain HTH_Tnp_Tc3_2 PF01498.18 KFM67334.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67334.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67335.1 - 9.1e-16 57.9 6.5 1.7e-15 57.0 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67335.1 - 1.8e-13 50.5 0.1 2.2e-12 47.0 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM67335.1 - 0.00086 19.9 1.5 0.00086 19.9 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67335.1 - 0.002 17.9 0.0 0.069 13.0 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67335.1 - 0.014 15.5 0.1 0.055 13.6 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM67335.1 - 0.029 14.4 2.1 0.037 14.1 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM67335.1 - 0.033 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 Tc3 transposase Ion_trans PF00520.31 KFM67336.1 - 8.9e-40 136.5 7.3 1.2e-39 136.0 7.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFM67336.1 - 1.3e-10 41.1 0.3 1.3e-10 41.1 0.3 2.9 3 0 0 3 3 3 1 Ion channel PAS_9 PF13426.7 KFM67336.1 - 0.00072 19.8 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 KFM67336.1 - 0.0021 18.1 0.0 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DegT_DnrJ_EryC1 PF01041.17 KFM67336.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2730 PF10805.8 KFM67337.1 - 0.075 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1464 PF07318.12 KFM67337.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) TIL PF01826.17 KFM67338.1 - 1.8e-12 47.3 14.2 2.4e-12 46.9 14.2 1.2 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain WD40 PF00400.32 KFM67339.1 - 2.3e-12 47.2 11.3 1.2e-07 32.2 0.1 7.3 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM67339.1 - 6.8e-06 26.3 1.0 3.1 8.2 0.0 5.1 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KFM67339.1 - 0.0025 17.7 2.0 2.2 8.2 0.0 2.8 1 1 1 2 2 2 2 Region in Clathrin and VPS Cu2_monoox_C PF03712.15 KFM67340.1 - 2.8e-63 212.1 0.2 4.7e-63 211.4 0.2 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KFM67340.1 - 6.6e-46 155.8 0.5 1.4e-45 154.7 0.2 1.7 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 KFM67340.1 - 1.7e-26 92.9 1.4 1.7e-26 92.9 1.4 2.2 2 0 0 2 2 2 1 DOMON domain Tail_tube PF10618.9 KFM67340.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein HTH_Tnp_Tc3_2 PF01498.18 KFM67341.1 - 4.7e-16 58.8 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67341.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67341.1 - 2.2e-07 30.5 1.2 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67341.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67341.1 - 2.9 8.6 15.0 0.12 13.0 1.9 3.4 2 1 1 3 3 3 0 Homeodomain-like domain NCU-G1 PF15065.6 KFM67342.1 - 3.1e-74 250.2 6.4 3.7e-74 249.9 6.4 1.0 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 RNase_PH PF01138.21 KFM67343.1 - 3.4e-14 53.5 0.0 4.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH PF01138.21 KFM67344.1 - 5.3e-21 75.5 0.0 1e-20 74.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFM67344.1 - 2.7e-16 59.3 0.1 6.3e-09 35.7 0.1 2.8 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 TACI-CRD2 PF09305.10 KFM67344.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.2 2 0 0 2 2 2 0 TACI, cysteine-rich domain Not3 PF04065.15 KFM67345.1 - 4.2e-90 301.2 28.4 7.6e-90 300.4 28.4 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KFM67345.1 - 2.2e-36 124.8 6.0 2.2e-36 124.8 6.0 2.6 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Hormone_1 PF00103.20 KFM67345.1 - 0.0044 16.8 2.0 0.0044 16.8 2.0 3.8 2 1 2 4 4 4 1 Somatotropin hormone family PulA_N1 PF17999.1 KFM67345.1 - 0.12 13.1 0.9 1.6 9.5 0.6 3.1 2 1 0 2 2 2 0 Pullulanase N1-terminal domain PI3K_P85_iSH2 PF16454.5 KFM67345.1 - 2.1 7.9 23.4 0.43 10.2 3.5 2.9 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GshA PF08886.11 KFM67346.1 - 0.078 11.5 0.3 0.11 11.0 0.3 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase Rhodanese PF00581.20 KFM67348.1 - 2.1e-13 50.7 0.0 2.7e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain MFS_1_like PF12832.7 KFM67349.1 - 6.3e-70 236.0 16.7 7.6e-70 235.7 16.7 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM67349.1 - 7.3e-14 51.4 42.4 4.6e-08 32.4 27.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFM67349.1 - 2.6e-12 46.4 15.0 2.6e-12 46.4 15.0 2.4 2 1 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 KFM67349.1 - 7.6e-10 38.1 28.4 5.2e-08 32.1 14.8 3.0 2 1 1 3 3 3 2 LacY proton/sugar symporter Vps39_2 PF10367.9 KFM67351.1 - 4.8e-21 75.2 1.8 4.8e-21 75.2 1.8 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 KFM67351.1 - 2.4e-17 63.1 4.2 3.7e-10 39.8 2.6 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS Vps39_1 PF10366.9 KFM67351.1 - 1e-13 51.5 2.7 3.4e-10 40.2 0.0 3.0 2 1 0 2 2 2 2 Vacuolar sorting protein 39 domain 1 FAST_1 PF06743.15 KFM67351.1 - 0.02 14.8 0.1 0.068 13.1 0.1 1.9 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 HTH_Tnp_Tc3_2 PF01498.18 KFM67352.1 - 5.1e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67352.1 - 2.5e-13 50.0 0.0 4.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67352.1 - 2.2e-07 30.5 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67352.1 - 0.0026 17.5 0.6 0.0076 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67352.1 - 2.1 9.0 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Vmethyltransf PF01660.17 KFM67354.1 - 1.3 7.9 6.0 5.3 5.8 0.1 2.1 1 1 0 2 2 2 0 Viral methyltransferase Pkinase PF00069.25 KFM67355.1 - 1.6e-68 230.9 0.0 2.6e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM67355.1 - 3.4e-50 170.7 0.0 5.2e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 KFM67355.1 - 6.7e-27 93.3 3.3 6.7e-27 93.3 3.3 2.4 3 0 0 3 3 3 1 C terminal SARAH domain of Mst1 Pkinase_fungal PF17667.1 KFM67355.1 - 3.1e-07 29.5 0.5 5.4e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase DUF1192 PF06698.11 KFM67355.1 - 0.011 15.8 0.3 0.053 13.6 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Nore1-SARAH PF16517.5 KFM67355.1 - 0.028 14.3 1.2 0.13 12.1 1.2 2.3 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Haspin_kinase PF12330.8 KFM67355.1 - 0.29 10.0 6.2 3 6.7 0.0 2.8 2 1 0 3 3 3 0 Haspin like kinase domain Phage_Mu_Gam PF07352.12 KFM67355.1 - 1.7 8.5 6.3 0.19 11.6 1.2 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein FMO-like PF00743.19 KFM67356.1 - 2.3e-65 221.0 0.0 2.7e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM67356.1 - 1.8e-15 57.0 0.2 6.6e-15 55.1 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM67356.1 - 5e-11 42.7 0.0 3.6e-08 33.5 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFM67356.1 - 6.5e-10 38.7 0.2 1.7e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KFM67356.1 - 4e-09 36.1 0.0 5.2e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM67356.1 - 1.2e-05 24.7 0.1 0.052 12.8 0.1 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KFM67356.1 - 0.00015 21.4 0.2 0.049 13.2 0.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Peptidase_M17_N PF02789.17 KFM67356.1 - 0.00026 20.9 0.1 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain NAD_binding_7 PF13241.6 KFM67356.1 - 0.00028 21.3 0.1 0.26 11.8 0.1 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KFM67356.1 - 0.00032 19.9 0.0 0.0073 15.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFM67356.1 - 0.00032 19.5 0.0 0.006 15.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.20 KFM67356.1 - 0.00036 20.6 0.0 0.24 11.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KFM67356.1 - 0.0008 19.9 0.1 0.42 11.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM67356.1 - 0.001 18.4 0.0 0.61 9.3 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 KFM67356.1 - 0.0055 16.7 0.0 0.17 11.9 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding IlvN PF07991.12 KFM67356.1 - 0.0079 15.8 0.1 0.18 11.4 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KFM67356.1 - 0.01 15.1 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KFM67356.1 - 0.014 14.8 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KFM67356.1 - 0.033 13.3 0.5 3 6.8 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.21 KFM67356.1 - 0.064 12.6 0.1 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 ThiF family NAD_Gly3P_dh_N PF01210.23 KFM67356.1 - 0.12 12.3 0.1 7.1 6.6 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TRAP-delta PF05404.12 KFM67359.1 - 4.5e-60 201.8 0.1 5.5e-60 201.6 0.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) HTH_33 PF13592.6 KFM67361.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix TnsD PF15978.5 KFM67361.1 - 0.037 13.0 0.1 0.042 12.8 0.1 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D DUF668 PF05003.12 KFM67361.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF668) FAST_1 PF06743.15 KFM67362.1 - 2.5e-06 27.3 1.1 2.5e-05 24.1 0.0 2.8 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFM67362.1 - 0.0034 17.5 0.0 0.26 11.4 0.0 3.2 3 0 0 3 3 3 1 RAP domain SPOC PF07744.13 KFM67362.1 - 0.048 13.6 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 SPOC domain SIR2 PF02146.17 KFM67363.1 - 3.1e-26 92.4 2.8 2.5e-19 69.9 0.0 3.4 2 1 1 3 3 3 2 Sir2 family TPP_enzyme_M PF00205.22 KFM67363.1 - 0.0023 17.7 0.0 0.024 14.4 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Fes1 PF08609.10 KFM67363.1 - 0.044 14.7 0.7 0.044 14.7 0.7 2.2 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 YabA PF06156.13 KFM67363.1 - 0.13 13.0 0.0 0.13 13.0 0.0 3.2 2 1 1 3 3 3 0 Initiation control protein YabA HrcA PF01628.21 KFM67363.1 - 0.14 12.1 1.2 0.31 10.9 1.2 1.5 1 0 0 1 1 1 0 HrcA protein C terminal domain zinc_ribbon_2 PF13240.6 KFM67363.1 - 0.22 11.3 2.8 0.55 10.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KFM67363.1 - 0.38 10.8 1.9 3 8.0 2.3 2.1 1 1 1 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 KFM67363.1 - 0.58 10.1 2.4 0.92 9.5 0.2 2.3 2 0 0 2 2 2 0 Nudix N-terminal CTNNB1_binding PF08347.11 KFM67364.1 - 5.4e-12 46.3 5.4 6.6e-12 46.0 5.4 1.3 1 1 0 1 1 1 1 N-terminal CTNNB1 binding zf-C2H2_jaz PF12171.8 KFM67365.1 - 4.9e-13 49.0 4.4 3.1e-08 33.7 0.2 4.8 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM67365.1 - 2.6e-12 46.7 26.9 8.1e-07 29.2 0.4 5.2 4 1 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFM67365.1 - 2.9e-07 30.8 18.2 0.19 12.1 0.2 5.5 5 1 0 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KFM67365.1 - 5e-07 29.4 11.6 0.0036 17.0 0.2 3.7 3 0 0 3 3 3 2 U1 zinc finger zf-CCHC_2 PF13696.6 KFM67365.1 - 0.01 15.6 6.1 0.12 12.2 0.7 3.2 3 0 0 3 3 3 0 Zinc knuckle Rpr2 PF04032.16 KFM67365.1 - 0.12 12.7 0.1 0.12 12.7 0.1 3.1 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_4 PF13894.6 KFM67365.1 - 0.14 13.1 15.3 2.9 9.0 0.4 5.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf_C2H2_13 PF18508.1 KFM67365.1 - 0.14 11.8 1.9 6.1 6.5 0.1 2.6 2 0 0 2 2 2 0 Zinc finger domain zf_UBZ PF18439.1 KFM67365.1 - 0.6 9.8 8.9 8.4 6.1 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFM67365.1 - 2.6 8.4 10.6 10 6.5 0.3 4.1 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Ephrin PF00812.17 KFM67366.1 - 4e-18 65.7 0.0 1.4e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Ephrin HTH_Tnp_Tc3_2 PF01498.18 KFM67367.1 - 6.4e-16 58.4 2.2 6.4e-16 58.4 2.2 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67367.1 - 1.5e-13 50.7 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67367.1 - 3.2e-07 30.0 1.6 7.8e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67367.1 - 0.003 17.3 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67368.1 - 7.7e-17 61.3 8.8 1.4e-15 57.3 6.5 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67368.1 - 7.4e-16 58.2 0.9 5.9e-15 55.3 0.0 2.5 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM67368.1 - 0.0012 19.4 1.1 0.0012 19.4 1.1 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67368.1 - 0.0023 17.7 0.1 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM67368.1 - 0.042 13.9 2.0 0.063 13.3 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Acyl_transf_3 PF01757.22 KFM67369.1 - 1e-12 47.8 42.3 1.6e-12 47.2 42.3 1.2 1 0 0 1 1 1 1 Acyltransferase family TPPK_C PF12555.8 KFM67369.1 - 0.048 13.7 1.5 1.7 8.7 0.1 2.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF5305 PF17231.2 KFM67369.1 - 0.64 9.4 2.5 0.56 9.6 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Pam17 PF08566.10 KFM67369.1 - 0.65 9.8 2.4 13 5.6 0.1 3.1 3 1 0 3 3 3 0 Mitochondrial import protein Pam17 LCAT PF02450.15 KFM67372.1 - 3.7e-67 227.2 0.6 4.2e-58 197.4 0.1 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 KFM67372.1 - 0.0097 15.6 0.2 0.053 13.2 0.0 2.2 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM67372.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KFM67372.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.12 KFM67372.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) 2OG-FeII_Oxy_2 PF13532.6 KFM67374.1 - 4.7e-08 33.5 0.0 6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DBB PF14545.6 KFM67375.1 - 0.088 12.7 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, Hus1 PF04005.12 KFM67376.1 - 3.9e-72 242.8 3.0 8.3e-72 241.8 3.0 1.5 1 1 0 1 1 1 1 Hus1-like protein Y_phosphatase PF00102.27 KFM67378.1 - 2.6e-73 246.5 1.4 1.3e-41 142.7 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM67378.1 - 0.0019 18.2 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM67378.1 - 0.023 14.8 0.0 0.062 13.4 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate 7TM_GPCR_Srw PF10324.9 KFM67380.1 - 8.9e-30 104.1 23.4 1.3e-29 103.5 23.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KFM67380.1 - 5e-29 101.4 16.9 6.8e-29 101.0 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0154 PF03672.13 KFM67380.1 - 0.084 12.9 0.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) UPF0542 PF15086.6 KFM67380.1 - 0.087 12.8 0.0 0.087 12.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 EVI2A PF05399.11 KFM67380.1 - 0.12 11.9 4.5 0.62 9.6 0.1 2.5 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) DUF4834 PF16118.5 KFM67380.1 - 1.6 9.7 11.0 1.9 9.5 0.4 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) DUF5326 PF17260.2 KFM67380.1 - 3.5 7.8 10.2 3.8 7.7 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5326) DUF3377 PF11857.8 KFM67380.1 - 3.6 7.6 6.9 8.9 6.3 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3377) DSPc PF00782.20 KFM67381.1 - 3.1e-32 111.2 0.1 3.9e-32 110.8 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM67381.1 - 0.00014 21.5 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFM67381.1 - 0.051 13.9 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Ribosomal_S15 PF00312.22 KFM67383.1 - 7.4e-11 42.1 0.9 1.5e-10 41.1 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 Adeno_E3_CR2 PF02439.15 KFM67384.1 - 10 6.0 13.4 3.2 7.6 4.1 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Suv3_C_1 PF18147.1 KFM67385.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 Pkinase_Tyr PF07714.17 KFM67386.1 - 0.00062 19.1 0.1 0.00088 18.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KFM67387.1 - 2.9e-33 115.2 0.0 3.4e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM67387.1 - 2.6e-17 63.1 0.0 4.1e-17 62.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFM67387.1 - 0.017 14.0 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Borrelia_orfD PF02999.14 KFM67387.1 - 0.028 14.8 0.1 0.046 14.0 0.1 1.5 1 1 0 1 1 1 0 Borrelia orf-D family Haspin_kinase PF12330.8 KFM67387.1 - 0.034 13.1 0.1 0.06 12.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFM67387.1 - 0.054 12.8 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_Tnp_Tc3_2 PF01498.18 KFM67390.1 - 3.4e-13 49.6 4.3 5.3e-13 49.0 4.3 1.3 1 0 0 1 1 1 1 Transposase WD40 PF00400.32 KFM67391.1 - 1.9e-21 76.0 10.2 2.3e-06 28.2 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KFM67391.1 - 2.2e-12 47.1 0.1 1.1e-11 44.8 0.0 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KFM67391.1 - 2.3e-05 24.6 0.1 0.00048 20.4 0.1 2.8 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM67391.1 - 3.8e-05 23.6 0.0 8.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A TFB6 PF17110.5 KFM67391.1 - 0.091 12.5 6.0 3.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH RNase_H2_suC PF08615.11 KFM67391.1 - 0.14 12.3 1.6 3.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM176 PF14851.6 KFM67391.1 - 1.1 9.0 11.5 0.29 10.8 0.9 2.2 2 0 0 2 2 2 0 FAM176 family BUD22 PF09073.10 KFM67391.1 - 1.4 8.2 10.1 2.1 7.6 10.1 1.2 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 KFM67391.1 - 1.5 8.8 6.7 11 5.9 1.1 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Importin_rep_4 PF18808.1 KFM67391.1 - 1.7 9.0 5.7 2.6 8.4 0.2 2.4 2 0 0 2 2 2 0 Importin repeat RXT2_N PF08595.11 KFM67391.1 - 3.2 7.7 11.0 0.73 9.8 0.6 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 KFM67391.1 - 3.4 7.4 14.3 0.081 12.6 0.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein KIND PF16474.5 KFM67391.1 - 3.6 7.4 11.0 8 6.3 0.9 2.2 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain Radial_spoke PF04712.12 KFM67391.1 - 4 6.3 9.4 0.26 10.2 0.2 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein Pox_Ag35 PF03286.14 KFM67391.1 - 9.6 5.9 13.8 0.68 9.7 1.1 2.6 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Med26 PF08711.11 KFM67392.1 - 2.1e-13 50.1 3.7 7.3e-13 48.3 3.7 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Med26_C PF15693.5 KFM67392.1 - 1e-06 29.0 0.3 1e-06 29.0 0.3 2.8 3 0 0 3 3 3 1 Mediator complex subunit 26 C-terminal SRA1 PF07304.11 KFM67393.1 - 4.1e-22 78.5 5.2 4.9e-22 78.3 4.8 1.4 1 1 0 1 1 1 1 Steroid receptor RNA activator (SRA1) RNA_pol_I_TF PF04090.12 KFM67393.1 - 0.0094 15.5 1.9 0.018 14.5 1.8 1.4 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor DUF2623 PF11115.8 KFM67394.1 - 0.0059 16.7 0.1 0.0085 16.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2623) zf-CCHC PF00098.23 KFM67394.1 - 5 7.4 11.7 3 8.1 2.3 3.0 3 0 0 3 3 3 0 Zinc knuckle HTH_Tnp_Tc3_2 PF01498.18 KFM67395.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67395.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_A17 PF05380.13 KFM67396.1 - 2.7e-28 99.0 0.5 6.9e-28 97.7 0.5 1.8 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF5641 PF18701.1 KFM67396.1 - 4.4e-23 81.3 0.1 1.7e-22 79.4 0.0 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5641) DUF1759 PF03564.15 KFM67396.1 - 8e-22 77.8 0.4 4.1e-21 75.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) HTH_Tnp_Tc3_2 PF01498.18 KFM67396.1 - 9.8e-15 54.6 0.6 9.8e-15 54.6 0.6 2.4 2 0 0 2 2 2 1 Transposase DUF1758 PF05585.12 KFM67396.1 - 6.7e-10 39.0 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) HTH_32 PF13565.6 KFM67396.1 - 0.0001 22.8 3.3 0.00015 22.3 1.7 2.2 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM67396.1 - 0.013 15.4 0.2 0.33 10.9 0.0 2.9 2 0 0 2 2 2 0 MarR family Asp_protease_2 PF13650.6 KFM67396.1 - 0.031 14.9 0.0 0.21 12.3 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease PAX PF00292.18 KFM67396.1 - 0.035 14.0 0.0 0.25 11.3 0.0 2.5 3 0 0 3 3 3 0 'Paired box' domain HTH_Crp_2 PF13545.6 KFM67396.1 - 0.14 12.2 1.1 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KFM67396.1 - 0.21 11.4 0.7 4.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 KFM67396.1 - 0.36 11.0 1.4 2.1 8.5 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain eIF3g PF12353.8 KFM67396.1 - 1.9 8.9 5.9 4.8 7.6 1.1 3.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G HTH_Tnp_Tc3_2 PF01498.18 KFM67397.1 - 7.3e-16 58.2 1.2 1.7e-15 57.0 1.2 1.7 1 0 0 1 1 1 1 Transposase DUF4371 PF14291.6 KFM67397.1 - 1.3e-09 38.0 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) HTH_32 PF13565.6 KFM67397.1 - 3.9e-05 24.2 2.5 8.9e-05 23.0 2.5 1.7 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 KFM67397.1 - 0.00028 20.7 0.2 0.076 12.9 0.0 2.6 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM67397.1 - 0.0057 16.6 1.9 0.029 14.4 0.1 2.9 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_3 PF01381.22 KFM67397.1 - 0.013 15.6 4.8 0.024 14.7 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix PAX PF00292.18 KFM67397.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 'Paired box' domain HTH_24 PF13412.6 KFM67397.1 - 0.026 14.1 4.1 0.39 10.3 0.0 3.7 3 1 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KFM67397.1 - 0.073 13.2 1.3 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 KFM67397.1 - 0.17 12.4 0.7 20 5.7 0.2 2.8 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Complex1_LYR PF05347.15 KFM67398.1 - 3.9e-12 46.0 3.0 7.3e-12 45.2 3.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFM67398.1 - 0.003 18.3 0.3 0.0048 17.6 0.3 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Ovate PF04844.13 KFM67399.1 - 0.0093 15.9 0.4 0.025 14.5 0.4 1.7 1 0 0 1 1 1 1 Transcriptional repressor, ovate FXa_inhibition PF14670.6 KFM67400.1 - 3e-35 120.2 52.1 5.8e-12 45.7 11.1 4.0 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFM67400.1 - 1e-26 92.5 16.9 1.6e-06 27.9 0.5 4.5 4 0 0 4 4 4 4 Complement Clr-like EGF-like RANK_CRD_2 PF18278.1 KFM67400.1 - 8.6e-06 25.8 24.2 0.012 15.7 1.0 4.5 4 0 0 4 4 4 3 Receptor activator of the NF-KB cysteine-rich repeat domain 2 EGF_3 PF12947.7 KFM67400.1 - 0.0018 18.4 49.9 0.053 13.7 9.1 4.7 4 0 0 4 4 4 3 EGF domain Toxin_21 PF08091.11 KFM67400.1 - 0.15 12.0 18.3 1.2 9.1 1.5 3.8 3 0 0 3 3 3 0 Spider insecticidal peptide EGF_CA PF07645.15 KFM67400.1 - 0.31 11.3 43.1 2.9 8.1 5.6 4.4 4 1 0 4 4 4 0 Calcium-binding EGF domain DUF4215 PF13948.6 KFM67400.1 - 1.8 9.1 43.0 2.2 8.8 2.3 6.1 3 2 1 4 4 4 0 Domain of unknown function (DUF4215) EGF PF00008.27 KFM67400.1 - 5.6 7.4 43.2 2.1 8.7 8.1 5.0 4 1 0 4 4 4 0 EGF-like domain Iso_dh PF00180.20 KFM67401.1 - 1.9e-75 254.2 0.0 2.3e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DGCR6 PF07324.11 KFM67403.1 - 1.1e-50 172.0 10.7 1.3e-50 171.8 10.7 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.9 KFM67403.1 - 0.00018 21.2 3.2 0.00018 21.2 3.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) Tox-ODYAM1 PF15642.6 KFM67403.1 - 1.3 7.9 9.7 1 8.3 8.0 1.5 1 1 0 2 2 2 0 Toxin in Odyssella and Amoebophilus LMBR1 PF04791.16 KFM67403.1 - 4.8 6.0 6.6 5.4 5.8 6.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein HTH_Tnp_Tc3_2 PF01498.18 KFM67404.1 - 4.8e-16 58.8 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67404.1 - 1.3e-13 50.9 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67404.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67404.1 - 0.0027 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67404.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HbrB PF08539.11 KFM67406.1 - 1.4e-05 25.2 0.3 0.00038 20.5 0.0 2.1 1 1 1 2 2 2 2 HbrB-like Colicin_im PF03857.13 KFM67406.1 - 0.026 14.5 0.1 0.083 12.8 0.1 1.7 2 0 0 2 2 2 0 Colicin immunity protein SET PF00856.28 KFM67407.1 - 7.4e-14 52.5 0.2 8.3e-14 52.3 0.2 1.0 1 0 0 1 1 1 1 SET domain PRC2_HTH_1 PF18118.1 KFM67408.1 - 1.1e-27 96.8 5.2 3.1e-27 95.3 0.0 2.9 3 0 0 3 3 3 1 Polycomb repressive complex 2 tri-helical domain preSET_CXC PF18264.1 KFM67408.1 - 4e-11 43.2 17.1 4e-11 43.2 17.1 3.6 2 1 0 2 2 2 1 CXC domain TFIID_NTD2 PF04494.15 KFM67408.1 - 0.87 9.8 0.0 0.87 9.8 0.0 2.6 3 0 0 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain MBT PF02820.18 KFM67410.1 - 8.8e-11 42.0 0.4 1.1e-10 41.7 0.4 1.2 1 0 0 1 1 1 1 mbt repeat Agenet PF05641.12 KFM67410.1 - 0.14 12.6 0.2 0.29 11.6 0.2 1.6 1 1 0 1 1 1 0 Agenet domain MBT PF02820.18 KFM67411.1 - 1.4e-23 83.0 0.0 1.6e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 mbt repeat MBT PF02820.18 KFM67412.1 - 3.2e-27 94.7 0.0 3.9e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 mbt repeat DUF1324 PF07038.11 KFM67412.1 - 0.29 11.4 2.1 14 6.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) MBT PF02820.18 KFM67413.1 - 3.1e-29 101.1 0.1 4.9e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 mbt repeat RRM_1 PF00076.22 KFM67416.1 - 1.5e-32 111.2 1.2 1.1e-16 60.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM67416.1 - 4.5e-15 55.6 0.5 4.4e-06 26.7 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KFM67416.1 - 2e-05 24.5 1.2 0.11 12.6 0.4 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 KFM67416.1 - 0.00024 21.1 0.2 0.15 12.1 0.1 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFM67416.1 - 0.0045 17.2 0.6 0.029 14.6 0.6 2.3 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF4857 PF16149.5 KFM67416.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4857) WD40 PF00400.32 KFM67417.1 - 2.2e-25 88.4 10.8 2.2e-07 31.5 0.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM67417.1 - 2.6e-17 62.9 4.8 2.7e-05 24.4 0.1 4.2 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM67417.1 - 9.2e-09 34.7 1.3 0.0017 17.4 1.2 3.2 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFM67417.1 - 4.2e-08 33.3 0.1 0.021 14.7 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A 7tm_1 PF00001.21 KFM67419.1 - 1.1e-72 244.5 6.2 1.6e-72 244.0 6.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM67419.1 - 4.8e-09 36.0 10.0 4.2e-08 32.9 3.0 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM67419.1 - 2.4e-05 24.1 11.9 2.4e-05 24.1 11.9 2.4 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFM67419.1 - 5.1e-05 23.2 12.9 0.00012 21.9 0.7 3.1 2 1 1 3 3 3 2 Olfactory receptor TMEM192 PF14802.6 KFM67419.1 - 0.062 12.4 2.7 5.2 6.1 0.1 2.5 2 0 0 2 2 2 0 TMEM192 family DUF996 PF06195.13 KFM67419.1 - 0.08 13.2 5.0 0.32 11.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF996) Orf78 PF06024.12 KFM67419.1 - 0.31 11.4 3.6 0.92 9.8 0.3 2.8 3 0 0 3 3 3 0 Orf78 (ac78) Srg PF02118.21 KFM67419.1 - 0.49 10.0 23.2 0.02 14.6 8.4 3.1 2 1 1 3 3 3 0 Srg family chemoreceptor LapA_dom PF06305.11 KFM67420.1 - 0.029 14.2 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2370 PF10176.9 KFM67420.1 - 0.051 13.2 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) BrkDBD PF09607.10 KFM67421.1 - 0.099 12.4 1.4 1 9.2 0.4 2.2 2 1 0 2 2 2 0 Brinker DNA-binding domain Hist_deacetyl PF00850.19 KFM67422.1 - 4.1e-46 157.9 0.0 4.8e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain MRP-S24 PF14955.6 KFM67423.1 - 4.2e-63 211.3 0.8 5e-63 211.1 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 Arm PF00514.23 KFM67424.1 - 1.1e-11 44.3 2.1 1.9e-05 24.6 0.5 3.2 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFM67424.1 - 0.00032 21.0 0.1 0.001 19.4 0.1 2.0 1 1 0 1 1 1 1 HEAT repeats DUF383 PF04063.14 KFM67424.1 - 0.0017 18.1 0.1 0.0019 17.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF383) V-ATPase_H_N PF03224.14 KFM67424.1 - 0.0039 16.5 0.0 0.0044 16.4 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_EZ PF13513.6 KFM67424.1 - 0.01 16.3 0.3 0.19 12.3 0.0 2.4 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 KFM67424.1 - 0.03 14.6 0.1 0.03 14.6 0.1 2.2 3 0 0 3 3 3 0 HEAT repeat DUF913 PF06025.12 KFM67424.1 - 0.11 11.5 0.1 5.7 5.8 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RasGEF_N_2 PF14663.6 KFM67424.1 - 0.16 12.4 0.2 0.27 11.7 0.2 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HMG_box_5 PF14887.6 KFM67426.1 - 0.082 12.9 0.0 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Arm PF00514.23 KFM67427.1 - 4.5e-08 32.9 0.0 0.00038 20.4 0.0 2.2 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat KAP PF05804.12 KFM67427.1 - 0.0031 15.7 0.2 0.0031 15.7 0.2 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Proteasom_PSMB PF10508.9 KFM67427.1 - 0.04 12.4 0.1 0.047 12.2 0.1 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Sushi PF00084.20 KFM67428.1 - 5.5e-10 39.7 7.8 1.4e-05 25.5 3.1 2.7 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Pyridoxal_deC PF00282.19 KFM67430.1 - 9.9e-15 54.1 0.2 1e-14 54.1 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain FPN1 PF06963.12 KFM67431.1 - 0.0014 17.2 0.3 0.0017 17.0 0.3 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) GOLD_2 PF13897.6 KFM67431.1 - 0.0069 16.9 2.6 0.0084 16.6 2.6 1.1 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking DUF3408 PF11888.8 KFM67431.1 - 0.0078 16.4 7.5 0.011 15.9 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3408) Na_trans_assoc PF06512.13 KFM67431.1 - 0.011 16.0 2.3 0.011 16.0 2.3 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Pinin_SDK_memA PF04696.13 KFM67431.1 - 0.015 15.4 6.6 0.02 14.9 6.6 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF4611 PF15387.6 KFM67431.1 - 0.02 15.1 9.5 0.031 14.5 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Folliculin PF11704.8 KFM67431.1 - 0.027 14.4 0.3 0.033 14.1 0.3 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport TRAP_alpha PF03896.16 KFM67431.1 - 0.032 13.4 3.0 0.038 13.2 3.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4666 PF15697.5 KFM67431.1 - 0.035 14.8 0.7 0.045 14.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) Radial_spoke PF04712.12 KFM67431.1 - 0.04 12.9 8.5 0.042 12.8 8.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.14 KFM67431.1 - 0.072 11.4 3.1 0.07 11.4 3.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1676 PF07898.13 KFM67431.1 - 0.1 12.7 1.1 0.12 12.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) PI3K_1B_p101 PF10486.9 KFM67431.1 - 0.12 10.1 2.6 0.13 10.1 2.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit COesterase PF00135.28 KFM67431.1 - 0.14 11.0 0.6 0.16 10.8 0.6 1.0 1 0 0 1 1 1 0 Carboxylesterase family DUF3499 PF12005.8 KFM67431.1 - 0.15 12.7 0.4 0.25 12.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Connexin PF00029.19 KFM67431.1 - 0.26 11.0 1.3 0.31 10.8 1.3 1.1 1 0 0 1 1 1 0 Connexin DUF2052 PF09747.9 KFM67431.1 - 0.34 11.0 12.8 0.5 10.5 12.7 1.3 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ureide_permease PF07168.11 KFM67431.1 - 0.56 8.9 1.7 0.63 8.7 1.7 1.1 1 0 0 1 1 1 0 Ureide permease NOA36 PF06524.12 KFM67431.1 - 0.77 9.0 6.3 0.89 8.8 6.3 1.2 1 0 0 1 1 1 0 NOA36 protein YqfQ PF14181.6 KFM67431.1 - 0.87 9.8 3.3 1.2 9.3 3.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein DNA_pol_phi PF04931.13 KFM67431.1 - 1 7.4 11.9 1.2 7.2 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Adeno_terminal PF02459.15 KFM67431.1 - 1.2 7.4 9.4 1.5 7.1 9.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF4637 PF15470.6 KFM67431.1 - 3.7 7.2 13.3 5.2 6.8 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PAC1 PF16094.5 KFM67431.1 - 5.7 6.0 10.6 8 5.5 10.6 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Dor1 PF04124.12 KFM67434.1 - 6.8e-112 373.5 3.7 1e-111 372.9 3.7 1.2 1 0 0 1 1 1 1 Dor1-like family DUF4201 PF13870.6 KFM67434.1 - 0.007 16.1 0.2 0.013 15.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Vps51 PF08700.11 KFM67434.1 - 0.0086 16.1 0.1 0.028 14.5 0.1 1.9 1 0 0 1 1 1 1 Vps51/Vps67 ZapB PF06005.12 KFM67434.1 - 0.09 13.2 0.7 0.27 11.7 0.2 2.1 2 0 0 2 2 2 0 Cell division protein ZapB RasGEF_N PF00618.20 KFM67434.1 - 4.2 7.7 7.0 7.6 6.8 1.9 3.4 2 1 1 3 3 3 0 RasGEF N-terminal motif OB_NTP_bind PF07717.16 KFM67436.1 - 9.7e-23 80.3 0.0 2.8e-22 78.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFM67436.1 - 1.7e-22 79.8 0.4 4e-21 75.3 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 KFM67436.1 - 8.1e-11 42.0 0.1 1.8e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM67436.1 - 2.9e-10 40.5 0.0 7.9e-09 35.8 0.0 2.8 3 0 0 3 3 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFM67436.1 - 1.3e-05 25.5 0.0 3.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM67436.1 - 8.5e-05 22.9 0.0 0.0003 21.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFM67436.1 - 0.00024 20.9 0.0 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFM67436.1 - 0.0038 16.6 0.0 0.0038 16.6 0.0 1.9 2 0 0 2 2 2 1 KaiC ResIII PF04851.15 KFM67436.1 - 0.0057 16.7 0.3 0.0057 16.7 0.3 2.9 2 1 1 3 3 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KFM67436.1 - 0.0065 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KFM67436.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2075 PF09848.9 KFM67436.1 - 0.029 13.6 1.4 0.047 12.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KFM67436.1 - 0.03 14.9 0.1 0.26 11.8 0.0 2.6 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.16 KFM67436.1 - 0.034 13.6 0.1 0.093 12.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 KFM67436.1 - 0.042 13.9 0.4 1 9.4 0.4 2.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM67436.1 - 0.05 13.5 0.1 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Integrin_beta PF00362.18 KFM67436.1 - 0.07 12.8 5.2 1.2 8.7 1.2 2.3 2 0 0 2 2 2 0 Integrin beta chain VWA domain AAA_16 PF13191.6 KFM67436.1 - 0.17 12.2 0.1 0.49 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 KFM67436.1 - 0.49 10.1 8.2 0.67 9.7 0.0 3.7 4 0 0 4 4 4 0 AAA domain Thioredoxin PF00085.20 KFM67437.1 - 1.9e-11 43.8 0.0 3.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin zf-C2H2_12 PF18658.1 KFM67438.1 - 0.0023 17.5 1.2 0.017 14.7 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger C2H2-type DUF678 PF05077.12 KFM67438.1 - 0.0078 16.3 0.1 0.011 15.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF678) DUF2847 PF11009.8 KFM67438.1 - 0.064 13.2 1.2 0.093 12.6 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2847) zf-C2H2_2 PF12756.7 KFM67438.1 - 0.11 12.8 11.8 0.15 12.5 3.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) BIR PF00653.21 KFM67438.1 - 0.14 12.9 0.2 0.14 12.9 0.2 1.9 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain GCV_T PF01571.21 KFM67442.1 - 1.9e-73 247.0 0.0 2.5e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KFM67442.1 - 1.2e-62 212.6 0.0 1.7e-62 212.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KFM67442.1 - 4e-16 58.7 0.0 9.1e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KFM67442.1 - 8e-14 51.7 0.5 1.6e-13 50.8 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_3 PF13738.6 KFM67442.1 - 5.3e-10 39.0 0.0 0.00053 19.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM67442.1 - 8e-06 26.0 1.9 0.00033 20.8 0.2 3.5 3 1 1 4 4 3 1 NAD(P)-binding Rossmann-like domain SoxG PF04268.12 KFM67442.1 - 9.5e-06 25.8 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Pyr_redox_2 PF07992.14 KFM67442.1 - 8.4e-05 21.9 0.0 0.00067 19.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM67442.1 - 0.00021 20.5 0.5 0.00058 19.1 0.5 1.7 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFM67442.1 - 0.0016 17.7 0.2 0.0028 16.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KFM67442.1 - 0.0041 15.9 0.0 0.76 8.4 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein ApbA PF02558.16 KFM67442.1 - 0.0062 16.2 0.2 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KFM67442.1 - 0.0063 16.5 0.1 0.25 11.3 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFM67442.1 - 0.011 16.3 0.0 0.13 12.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM67442.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KFM67442.1 - 0.033 13.3 0.0 0.17 10.9 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 KFM67442.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase TrkA_N PF02254.18 KFM67442.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain S-methyl_trans PF02574.16 KFM67443.1 - 2.1e-45 155.6 0.0 2.5e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase SNARE PF05739.19 KFM67445.1 - 0.016 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 SNARE domain Bacillus_HBL PF05791.11 KFM67445.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) GCFC PF07842.12 KFM67447.1 - 0.027 14.1 0.4 0.05 13.2 0.4 1.4 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein SRI PF08236.11 KFM67447.1 - 0.032 14.4 0.1 0.057 13.6 0.1 1.4 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Atg14 PF10186.9 KFM67450.1 - 0.0088 15.2 12.5 0.011 14.9 12.5 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 FDF PF09532.10 KFM67450.1 - 0.24 12.3 4.1 0.39 11.6 4.1 1.4 1 0 0 1 1 1 0 FDF domain TMPIT PF07851.13 KFM67450.1 - 1.9 7.7 15.8 1.9 7.7 15.0 1.4 1 1 0 1 1 1 0 TMPIT-like protein PRP38 PF03371.15 KFM67451.1 - 1.3e-62 210.8 0.5 1.6e-62 210.5 0.5 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KFM67451.1 - 8.7e-05 23.1 42.1 0.00016 22.2 42.1 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DivIVA PF05103.13 KFM67451.1 - 0.36 10.9 3.1 1.1 9.4 0.7 2.2 1 1 1 2 2 2 0 DivIVA protein CDC45 PF02724.14 KFM67451.1 - 1.4 7.1 20.7 1.7 6.9 20.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SWIRM-assoc_2 PF16496.5 KFM67451.1 - 2.4 6.9 18.2 3.7 6.3 18.2 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Use1 PF09753.9 KFM67451.1 - 3.7 7.2 12.7 4.7 6.9 12.7 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 V_ATPase_I PF01496.19 KFM67451.1 - 3.8 5.3 5.7 4.8 5.0 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RT_RNaseH_2 PF17919.1 KFM67452.1 - 0.00011 22.2 0.0 0.00013 22.0 0.0 1.2 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM67452.1 - 0.0056 17.0 0.0 0.0061 16.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PIF1 PF05970.14 KFM67453.1 - 3.6e-20 72.4 0.0 4.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFM67453.1 - 0.078 12.7 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DDE_3 PF13358.6 KFM67455.1 - 5.1e-06 26.3 0.1 6.1e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TTL PF03133.15 KFM67456.1 - 7.9e-27 94.1 0.0 9.5e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family TTL PF03133.15 KFM67458.1 - 3e-21 75.8 0.1 3.2e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KFM67458.1 - 6.5e-05 22.3 0.0 6.9e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 KFM67458.1 - 0.00015 21.1 0.0 0.00017 20.9 0.0 1.0 1 0 0 1 1 1 1 YheC/D like ATP-grasp RimK PF08443.11 KFM67458.1 - 0.073 12.7 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 RimK-like ATP-grasp domain HTH_Tnp_Tc3_2 PF01498.18 KFM67459.1 - 2e-17 63.2 1.4 6.9e-16 58.3 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67459.1 - 1.5e-13 50.7 0.0 2.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM67459.1 - 6.1 7.5 9.9 0.2 12.3 2.3 2.5 2 0 0 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.6 KFM67460.1 - 4.5e-16 58.9 0.1 5.5e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67460.1 - 7.1e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM67460.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67460.1 - 0.0024 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67460.1 - 0.014 15.5 0.1 0.063 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM67460.1 - 0.033 14.2 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM67461.1 - 2.2e-16 59.9 2.2 6.5e-16 58.4 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67461.1 - 1.5e-13 50.8 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67461.1 - 2.9e-07 30.1 1.6 7.8e-07 28.8 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67461.1 - 0.0025 17.6 0.6 0.0084 15.9 0.6 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67461.1 - 2.9 8.5 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_32 PF13565.6 KFM67462.1 - 0.00021 21.8 0.1 0.0048 17.5 0.1 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67462.1 - 0.0092 16.2 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 Transposase HTH_9 PF08221.11 KFM67462.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_24 PF13412.6 KFM67462.1 - 0.016 14.7 0.6 0.081 12.5 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF3375 PF11855.8 KFM67462.1 - 0.06 12.3 0.1 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) HTH_Tnp_Tc3_2 PF01498.18 KFM67463.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67463.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67463.1 - 2e-07 30.6 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67463.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67463.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM67464.1 - 6.3e-16 58.4 0.1 6.7e-15 55.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67464.1 - 8.5e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM67464.1 - 0.00079 20.0 1.5 0.00079 20.0 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67464.1 - 0.031 14.1 0.2 1.2 9.0 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67466.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67466.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67466.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67466.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67466.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ATG7_N PF16420.5 KFM67470.1 - 6.1e-87 292.0 0.0 8.6e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KFM67470.1 - 1.1e-42 146.2 0.0 1.6e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KFM67470.1 - 0.077 13.0 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KFM67470.1 - 0.14 11.5 0.0 0.57 9.5 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Auts2 PF15336.6 KFM67471.1 - 3e-40 138.7 7.3 3e-40 138.7 7.3 4.6 4 2 1 5 5 5 1 Autism susceptibility gene 2 protein Peptidase_M13 PF01431.21 KFM67474.1 - 2.4e-25 89.4 0.0 2.5e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 DDE_3 PF13358.6 KFM67475.1 - 1.1e-06 28.4 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Homeobox_KN PF05920.11 KFM67476.1 - 1.3e-15 57.0 0.4 1.3e-15 57.0 0.4 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KFM67476.1 - 2.8e-07 30.3 1.9 5.1e-07 29.4 1.9 1.4 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 KFM67476.1 - 0.11 13.0 0.2 0.23 12.0 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 HTH_Tnp_Tc3_2 PF01498.18 KFM67477.1 - 2.2e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67477.1 - 9.1e-14 51.4 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_HII PF01351.18 KFM67478.1 - 1.7e-18 67.2 0.1 2e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease HII Kinesin PF00225.23 KFM67479.1 - 3.2e-89 299.1 0.1 4.3e-89 298.7 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM67479.1 - 7.4e-20 71.4 0.2 9.9e-15 54.8 0.1 2.5 2 0 0 2 2 2 2 Microtubule binding UPF0242 PF06785.11 KFM67480.1 - 0.0024 18.0 23.6 0.0024 18.0 23.6 5.0 1 1 4 5 5 5 1 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 KFM67480.1 - 0.85 8.1 9.4 0.19 10.2 6.2 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF3584 PF12128.8 KFM67480.1 - 4.9 4.5 69.2 0.67 7.4 37.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 KFM67480.1 - 9.8 6.2 52.2 0.098 12.7 6.5 4.9 2 1 3 6 6 6 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 KFM67481.1 - 0.0062 16.6 12.8 0.0062 16.6 12.8 5.3 2 1 1 5 5 5 1 Designed helical repeat protein 10 domain TPR_2 PF07719.17 KFM67481.1 - 0.13 12.5 0.9 20 5.6 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ASRT PF07100.11 KFM67481.1 - 0.17 12.0 3.6 0.44 10.6 0.1 3.0 3 0 0 3 3 3 0 Anabaena sensory rhodopsin transducer PI_PP_I PF18363.1 KFM67481.1 - 1.4 9.2 11.0 1 9.6 0.2 4.0 4 1 0 4 4 4 0 Phosphoinositide phosphatase insertion domain LPP PF04728.13 KFM67481.1 - 3 8.3 19.6 4.7 7.7 0.4 5.9 4 3 1 5 5 5 0 Lipoprotein leucine-zipper FUSC PF04632.12 KFM67481.1 - 3.5 6.1 4.3 1.8 7.0 1.3 1.6 2 1 0 2 2 2 0 Fusaric acid resistance protein family DUF4055 PF13264.6 KFM67481.1 - 9.5 6.4 15.9 7.5 6.7 1.0 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4055) NPV_P10 PF05531.12 KFM67481.1 - 9.6 6.8 20.0 5.5 7.5 0.5 5.3 3 1 3 6 6 6 0 Nucleopolyhedrovirus P10 protein HTH_Tnp_Tc3_2 PF01498.18 KFM67483.1 - 1.9e-16 60.0 0.4 3.6e-16 59.2 0.4 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM67483.1 - 0.0014 19.2 6.0 0.002 18.7 1.8 2.3 2 0 0 2 2 2 1 Homeodomain-like domain PAX PF00292.18 KFM67483.1 - 0.0059 16.5 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 'Paired box' domain HTH_Crp_2 PF13545.6 KFM67483.1 - 0.093 12.7 1.0 0.71 9.9 0.1 2.3 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain DUF5641 PF18701.1 KFM67484.1 - 9e-24 83.5 0.5 2.3e-23 82.2 0.2 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5641) Peptidase_A17 PF05380.13 KFM67484.1 - 1.9e-19 70.2 0.1 3.7e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 KFM67484.1 - 0.061 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CppA_C PF14507.6 KFM67485.1 - 0.0072 17.0 0.5 0.026 15.2 0.1 2.0 2 1 0 2 2 2 1 CppA C-terminal DUF863 PF05904.11 KFM67485.1 - 0.015 13.8 2.4 0.013 13.9 2.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) DUF1758 PF05585.12 KFM67485.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) HTH_Tnp_Tc3_2 PF01498.18 KFM67486.1 - 1.3e-17 63.8 1.4 2.4e-17 62.9 1.4 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM67486.1 - 3.3e-07 30.8 7.0 2.7e-06 27.9 2.6 2.4 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM67486.1 - 0.00028 20.7 0.7 0.022 14.6 0.1 2.5 2 0 0 2 2 2 1 MarR family HTH_3 PF01381.22 KFM67486.1 - 0.00053 20.0 0.7 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 KFM67486.1 - 0.0025 17.9 3.1 0.026 14.6 0.4 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_3 PF13358.6 KFM67486.1 - 0.0042 16.9 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.18 KFM67486.1 - 0.0082 16.1 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 'Paired box' domain HTH_Crp_2 PF13545.6 KFM67486.1 - 0.013 15.4 1.3 0.079 12.9 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KFM67486.1 - 0.05 13.4 4.8 0.12 12.2 0.1 2.7 3 0 0 3 3 3 0 Homeodomain-like domain HTH_24 PF13412.6 KFM67486.1 - 0.072 12.7 1.7 1.3 8.6 0.0 2.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 KFM67486.1 - 0.18 12.2 0.4 11 6.5 0.2 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_29 PF13551.6 KFM67486.1 - 0.23 11.5 1.6 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 Winged helix-turn helix DUF229 PF02995.17 KFM67487.1 - 9.4e-120 400.5 3.2 1.5e-119 399.9 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Fasciclin PF02469.22 KFM67489.1 - 8.1e-22 77.8 0.0 2.1e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Fasciclin domain zf-H2C2_2 PF13465.6 KFM67491.1 - 8.3e-20 70.3 10.5 5.5e-08 32.9 0.6 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67491.1 - 2.2e-19 68.7 16.4 4.2e-06 26.9 0.6 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67491.1 - 1.5e-13 50.3 15.3 0.00015 22.3 0.5 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM67491.1 - 2.3e-07 30.4 5.9 0.0012 18.5 0.1 4.1 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFM67491.1 - 7.3e-07 29.4 19.9 0.0039 17.5 1.4 3.6 4 0 0 4 4 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM67491.1 - 2.2e-06 27.8 8.2 0.16 12.3 0.4 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM67491.1 - 3.6e-05 23.6 18.3 0.0014 18.6 1.3 3.7 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM67491.1 - 8e-05 22.4 10.7 0.047 13.6 0.2 4.3 5 0 0 5 5 4 2 zinc-finger of a C2HC-type GAGA PF09237.11 KFM67491.1 - 0.00011 21.9 2.4 0.01 15.6 0.2 2.9 1 1 2 3 3 3 1 GAGA factor zf-DBF PF07535.12 KFM67491.1 - 0.00036 20.6 6.5 1.8 8.7 0.2 3.4 2 1 1 3 3 3 2 DBF zinc finger zf-Sec23_Sec24 PF04810.15 KFM67491.1 - 0.00042 20.3 7.5 0.71 10.0 0.1 3.4 2 1 2 4 4 3 2 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM67491.1 - 0.00073 19.3 6.9 1.1 9.1 0.3 3.2 2 1 1 3 3 3 2 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFM67491.1 - 0.0014 18.7 3.2 1.7 8.9 0.1 3.3 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFM67491.1 - 0.0028 18.4 4.6 0.46 11.3 1.5 2.1 1 1 1 2 2 2 2 zinc-ribbon family zf-C2H2_11 PF16622.5 KFM67491.1 - 0.004 16.9 14.9 0.31 10.8 1.0 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-BED PF02892.15 KFM67491.1 - 0.0092 16.0 14.6 0.24 11.5 2.6 3.2 1 1 2 3 3 3 2 BED zinc finger TRAF6_Z2 PF18048.1 KFM67491.1 - 0.014 15.4 7.4 0.35 11.0 0.6 2.8 3 0 0 3 3 2 0 TNF receptor-associated factor 6 zinc finger 2 BolA PF01722.18 KFM67491.1 - 0.019 15.2 0.2 3.9 7.8 0.0 2.5 1 1 1 2 2 2 0 BolA-like protein zf-RRPl_C4 PF17026.5 KFM67491.1 - 0.023 14.8 6.5 0.037 14.1 6.2 1.5 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf_UBZ PF18439.1 KFM67491.1 - 0.028 14.0 9.1 2.6 7.7 0.2 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 KFM67491.1 - 0.054 13.5 5.7 1.8 8.6 1.6 3.3 2 1 2 4 4 4 0 Adenylate kinase, active site lid DUF2757 PF10955.8 KFM67491.1 - 0.055 13.7 5.2 5.7 7.3 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2757) zf-C2H2_2 PF12756.7 KFM67491.1 - 0.071 13.5 12.5 0.57 10.5 1.0 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Cas_CXXC_CXXC PF09706.10 KFM67491.1 - 0.14 12.4 7.8 0.91 9.8 0.1 3.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-RING_UBOX PF13445.6 KFM67491.1 - 0.16 12.0 5.3 23 5.1 0.1 3.7 4 0 0 4 4 4 0 RING-type zinc-finger zf-UBP PF02148.19 KFM67491.1 - 0.17 12.2 7.7 6.6 7.1 8.2 2.2 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-MYST PF17772.1 KFM67491.1 - 0.2 11.3 7.4 3.4 7.3 0.2 3.1 1 1 2 3 3 3 0 MYST family zinc finger domain HNH PF01844.23 KFM67491.1 - 0.25 11.5 8.0 11 6.3 0.5 3.4 3 0 0 3 3 3 0 HNH endonuclease FYVE PF01363.21 KFM67491.1 - 0.3 11.3 11.9 5.8 7.1 10.6 3.0 2 1 1 3 3 2 0 FYVE zinc finger DUF5402 PF17393.2 KFM67491.1 - 0.31 11.0 6.7 20 5.1 0.2 3.1 1 1 2 3 3 3 0 Family of unknown function (DUF5402) gag_pre-integrs PF13976.6 KFM67491.1 - 0.33 10.8 11.3 3.3 7.7 0.9 3.2 1 1 2 3 3 3 0 GAG-pre-integrase domain Sgf11 PF08209.11 KFM67491.1 - 0.35 10.5 6.5 4.7 6.8 0.2 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Vps36-NZF-N PF16988.5 KFM67491.1 - 0.39 10.1 7.9 1.8 8.0 0.2 2.8 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn-C2H2_12 PF18112.1 KFM67491.1 - 1 9.9 12.1 3.2 8.3 0.4 3.8 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain NTP_transf_7 PF07984.12 KFM67492.1 - 1.6e-160 533.7 0.6 1.8e-160 533.5 0.6 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase Transket_pyr PF02779.24 KFM67493.1 - 1e-41 142.6 0.0 1.3e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFM67493.1 - 3.1e-33 114.3 0.0 5.1e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Ribosomal_S22 PF08136.11 KFM67493.1 - 0.06 13.7 0.0 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 30S ribosomal protein subunit S22 family CSN7a_helixI PF18392.1 KFM67494.1 - 1.2e-16 60.3 4.8 2.1e-16 59.6 4.8 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 KFM67494.1 - 4.2e-09 36.9 0.3 1.2e-08 35.4 0.3 1.8 1 0 0 1 1 1 1 PCI domain Methyltransf_2 PF00891.18 KFM67494.1 - 0.082 12.2 0.2 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain DUF1664 PF07889.12 KFM67494.1 - 0.13 12.3 2.4 0.25 11.4 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ABC2_membrane PF01061.24 KFM67495.1 - 0.00035 20.1 4.7 0.00035 20.1 4.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane PF01061.24 KFM67496.1 - 6.1e-12 45.4 0.2 6.4e-12 45.3 0.2 1.0 1 0 0 1 1 1 1 ABC-2 type transporter Ig_3 PF13927.6 KFM67497.1 - 1.5e-17 63.9 1.9 3.4e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM67497.1 - 2.5e-13 50.1 0.4 1.6e-07 31.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM67497.1 - 9.9e-09 35.2 0.0 1.3e-05 25.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM67497.1 - 1.7e-07 31.3 0.0 0.0021 18.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFM67497.1 - 0.073 13.5 0.1 1.2 9.5 0.1 2.3 2 1 0 2 2 2 0 Immunoglobulin C1-set domain DUF3305 PF11749.8 KFM67498.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) zf-CCHC PF00098.23 KFM67500.1 - 1.6e-06 27.9 2.5 2.4e-06 27.3 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM67500.1 - 0.036 13.8 0.6 0.062 13.0 0.6 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM67500.1 - 0.057 13.2 0.8 0.091 12.5 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle HTH_Tnp_Tc3_2 PF01498.18 KFM67502.1 - 4.9e-16 58.7 3.5 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67502.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67502.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67502.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67502.1 - 2 9.1 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Receptor_2B4 PF11465.8 KFM67503.1 - 0.052 13.7 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 7tm_1 PF00001.21 KFM67504.1 - 0.00086 18.7 0.2 0.00086 18.7 0.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HTH_Tnp_Tc3_2 PF01498.18 KFM67505.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67505.1 - 2.3e-12 46.9 0.0 3.8e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67507.1 - 1.7e-11 44.2 0.5 8.4e-11 42.0 0.3 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67507.1 - 2.4e-11 43.6 0.0 3.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease CRAL_TRIO PF00650.20 KFM67508.1 - 2.8e-24 85.6 0.0 4e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM67508.1 - 0.0014 18.8 0.2 0.0027 17.9 0.0 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM67508.1 - 0.0043 17.2 0.1 0.015 15.5 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain 7tm_1 PF00001.21 KFM67509.1 - 2.5e-44 151.6 9.9 3e-44 151.3 9.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM67509.1 - 4.7e-11 42.5 12.1 5.9e-11 42.2 12.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFM67509.1 - 0.0007 19.0 3.1 0.0017 17.8 3.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Guanylate_cyc PF00211.20 KFM67510.1 - 2.5e-55 187.0 0.1 4.4e-55 186.1 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KFM67510.1 - 2.9e-21 75.9 0.0 4.5e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM67510.1 - 5e-15 55.6 0.1 1e-14 54.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain HNOBA PF07701.14 KFM67510.1 - 9.3e-06 25.2 1.9 1.4e-05 24.7 1.9 1.2 1 0 0 1 1 1 1 Heme NO binding associated Cor1 PF04803.12 KFM67510.1 - 0.011 15.9 1.1 0.019 15.2 1.1 1.3 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region HTH_Tnp_Tc3_2 PF01498.18 KFM67511.1 - 1.5e-17 63.6 1.5 6.6e-16 58.3 2.2 2.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67511.1 - 1.6e-13 50.7 0.0 2.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67511.1 - 3.2e-07 30.0 1.6 7.9e-07 28.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67511.1 - 0.003 17.3 0.6 0.0086 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67511.1 - 2.7 8.7 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Hemopexin PF00045.19 KFM67514.1 - 1e-55 185.4 20.7 2.7e-15 56.0 0.3 4.5 4 0 0 4 4 4 4 Hemopexin Peptidase_M10 PF00413.24 KFM67514.1 - 1.7e-55 187.2 0.3 3.6e-55 186.1 0.3 1.6 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 KFM67514.1 - 7.5e-10 38.9 0.0 1.7e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain DUF4953 PF16313.5 KFM67514.1 - 0.0036 16.6 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 Met-zincin Reprolysin_5 PF13688.6 KFM67514.1 - 0.0045 17.2 0.9 0.013 15.6 0.1 2.1 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFM67514.1 - 0.0087 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KFM67514.1 - 0.013 16.0 0.5 0.038 14.5 0.5 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFM67514.1 - 0.015 14.9 0.1 0.73 9.4 0.0 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 KFM67514.1 - 0.091 12.4 0.2 0.22 11.1 0.1 1.6 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase ATP-grasp_2 PF08442.10 KFM67515.1 - 7.6e-75 250.9 1.7 7.6e-75 250.9 1.7 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KFM67515.1 - 1.1e-26 93.5 1.0 2.2e-26 92.5 1.0 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFM67515.1 - 2.9e-10 40.0 0.1 5e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFM67515.1 - 0.00012 21.9 1.1 0.0008 19.2 0.3 2.5 2 1 1 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KFM67515.1 - 0.021 14.4 0.0 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp PF02222.22 KFM67515.1 - 0.023 14.3 0.1 0.085 12.4 0.1 1.9 1 1 1 2 2 2 0 ATP-grasp domain PASTA PF03793.19 KFM67515.1 - 0.029 14.2 0.0 18 5.3 0.0 3.3 3 0 0 3 3 3 0 PASTA domain OKR_DC_1_N PF03709.15 KFM67515.1 - 0.1 12.9 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Actin PF00022.19 KFM67516.1 - 4.1e-145 483.5 0.0 4.6e-145 483.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFM67516.1 - 0.0042 16.0 0.0 1.1 8.1 0.0 2.5 2 1 0 2 2 2 2 MreB/Mbl protein ACBP PF00887.19 KFM67517.1 - 3e-22 78.6 0.0 6.1e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Pex24p PF06398.11 KFM67517.1 - 0.08 11.9 0.5 0.12 11.3 0.4 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin NOC3p PF07540.11 KFM67518.1 - 2.3e-24 85.7 3.9 3.3e-24 85.2 0.7 2.8 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KFM67518.1 - 1.4e-20 74.0 0.0 1.4e-20 74.0 0.0 2.0 2 0 0 2 2 2 1 CBF/Mak21 family 7tm_2 PF00002.24 KFM67520.1 - 4.6e-09 35.9 8.1 6.2e-09 35.5 7.1 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 KFM67520.1 - 0.033 13.3 5.9 0.32 10.0 0.0 2.1 1 1 0 2 2 2 0 Frizzled/Smoothened family membrane region Methuselah_N PF06652.12 KFM67521.1 - 0.011 15.6 1.0 0.39 10.6 0.3 2.2 1 1 1 2 2 2 0 Methuselah N-terminus 7tm_2 PF00002.24 KFM67521.1 - 0.15 11.3 0.2 0.15 11.3 0.2 1.8 2 1 0 2 2 2 0 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.24 KFM67522.1 - 5.9e-13 48.7 4.8 7.1e-13 48.4 4.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) ABC2_membrane_2 PF12679.7 KFM67522.1 - 5.3 6.2 10.5 0.3 10.3 2.2 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein FA_hydroxylase PF04116.13 KFM67523.1 - 1.8e-22 80.1 13.7 2e-22 79.9 13.7 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily ELM2 PF01448.24 KFM67524.1 - 3.8e-07 30.8 0.0 8.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 KFM67524.1 - 0.00013 21.8 2.0 0.00027 20.8 2.0 1.5 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KFM67524.1 - 0.00024 21.2 0.1 0.00044 20.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain EELM2 PF15863.5 KFM67524.1 - 0.0098 16.0 0.1 0.023 14.8 0.0 1.7 1 1 1 2 2 2 1 Extended EGL-27 and MTA1 homology domain MR_MLE_C PF13378.6 KFM67524.1 - 0.038 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Enolase C-terminal domain-like FA_hydroxylase PF04116.13 KFM67525.1 - 0.0017 18.7 3.8 0.0018 18.6 3.8 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DDE_3 PF13358.6 KFM67526.1 - 5.1e-16 58.7 0.1 5.9e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67526.1 - 7.9e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM67526.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67526.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67526.1 - 0.015 15.4 0.1 0.065 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM67526.1 - 0.035 14.1 0.4 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDE_Tnp_1_7 PF13843.6 KFM67527.1 - 8.9e-77 258.7 0.0 1.1e-76 258.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM67527.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 KFM67527.1 - 0.027 14.5 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Zot PF05707.12 KFM67527.1 - 0.055 13.1 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) HTH_Tnp_Tc3_2 PF01498.18 KFM67528.1 - 2.2e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67528.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM67529.1 - 5e-16 58.8 0.1 5.5e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67529.1 - 7.1e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM67529.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67529.1 - 0.0025 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67529.1 - 0.015 15.4 0.1 0.063 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM67529.1 - 0.034 14.2 0.4 0.034 14.2 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM67530.1 - 2e-16 60.0 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67530.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank_4 PF13637.6 KFM67531.1 - 2e-12 47.4 1.0 1.4e-05 25.6 0.1 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM67531.1 - 6.6e-12 45.9 0.4 1.3e-08 35.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM67531.1 - 5.7e-07 29.7 1.1 0.014 15.7 0.3 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM67531.1 - 5.9e-07 29.3 0.8 0.012 16.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KFM67531.1 - 0.00011 22.5 3.2 0.028 14.9 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KFM67532.1 - 1.3e-39 134.6 0.9 3.4e-16 59.6 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM67532.1 - 1.7e-29 101.8 0.7 2.5e-14 53.4 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM67532.1 - 5.9e-19 67.9 5.2 1.2e-07 31.9 0.0 5.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFM67532.1 - 3.9e-18 65.0 5.8 0.019 15.4 0.1 5.6 5 1 1 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KFM67532.1 - 7.3e-18 62.8 2.2 0.0017 18.7 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Dynein_light PF01221.18 KFM67534.1 - 4e-18 65.5 0.1 4.3e-18 65.4 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 MMM1 PF10296.9 KFM67535.1 - 0.026 13.6 0.0 0.032 13.3 0.0 1.0 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Ribosomal_S21e PF01249.18 KFM67536.1 - 8.7e-43 144.3 0.3 9.7e-43 144.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e PH_RBD PF12068.8 KFM67540.1 - 0.073 12.5 0.4 0.14 11.7 0.4 1.4 1 0 0 1 1 1 0 Rab-binding domain (RBD) Plant_zn_clust PF10533.9 KFM67540.1 - 0.58 10.2 3.7 10 6.2 0.2 2.6 2 0 0 2 2 2 0 Plant zinc cluster domain SH3_1 PF00018.28 KFM67542.1 - 2e-08 33.7 0.0 3.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM67542.1 - 2.9e-05 23.8 0.0 4.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.16 KFM67542.1 - 0.00028 21.0 0.2 0.00064 19.8 0.2 1.6 1 1 0 1 1 1 1 Hr1 repeat COG5 PF10392.9 KFM67542.1 - 0.014 15.6 0.1 0.026 14.7 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 SH3_3 PF08239.11 KFM67542.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Uds1 PF15456.6 KFM67542.1 - 0.022 14.9 0.4 0.07 13.3 0.4 1.8 1 1 0 1 1 1 0 Up-regulated During Septation Tiam_CC_Ex PF18385.1 KFM67542.1 - 0.037 14.4 0.2 0.1 13.0 0.0 1.7 1 1 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain DUF4349 PF14257.6 KFM67542.1 - 0.13 11.6 0.2 0.21 11.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) FCH PF00611.23 KFM67543.1 - 1.3e-17 63.8 1.1 1.3e-17 63.8 1.1 2.9 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain TPR_1 PF00515.28 KFM67543.1 - 0.0044 16.8 3.8 0.11 12.4 0.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM67543.1 - 0.009 16.2 5.2 0.058 13.6 1.4 3.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM67543.1 - 0.014 15.4 2.3 0.12 12.6 0.6 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM67543.1 - 0.28 10.9 2.0 11 5.7 0.2 2.5 1 1 1 2 2 2 0 TPR repeat DUF5347 PF17282.2 KFM67543.1 - 2.5 8.4 9.8 0.38 11.1 2.2 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5347) zf-C4H2 PF10146.9 KFM67543.1 - 4.4 7.6 20.1 15 5.8 17.8 2.4 1 1 0 1 1 1 0 Zinc finger-containing protein ABC_membrane PF00664.23 KFM67544.1 - 2.1e-23 83.4 2.3 4.6e-23 82.2 1.6 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_membrane PF00664.23 KFM67545.1 - 7.4e-21 75.0 0.4 9e-21 74.7 0.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Y_phosphatase PF00102.27 KFM67546.1 - 8.2e-50 169.6 0.0 9.2e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM67546.1 - 0.0011 18.7 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM67546.1 - 0.0029 17.6 0.0 0.0055 16.7 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family CRAL_TRIO PF00650.20 KFM67547.1 - 7.4e-28 97.3 0.0 1.4e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Y_phosphatase PF00102.27 KFM67547.1 - 6.7e-14 52.0 0.7 5e-13 49.2 0.4 2.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CRAL_TRIO_2 PF13716.6 KFM67547.1 - 9.1e-10 38.8 0.0 1.8e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain THAP PF05485.12 KFM67548.1 - 2.2e-15 57.3 0.1 2.2e-15 57.3 0.1 2.3 3 0 0 3 3 3 1 THAP domain SOGA PF11365.8 KFM67548.1 - 0.0039 18.3 1.8 0.0045 18.1 0.7 1.7 2 0 0 2 2 2 1 Protein SOGA bZIP_1 PF00170.21 KFM67548.1 - 0.013 15.5 3.0 0.034 14.3 3.0 1.7 1 0 0 1 1 1 0 bZIP transcription factor SPT2 PF08243.11 KFM67548.1 - 0.022 15.3 1.7 0.038 14.5 1.7 1.4 1 0 0 1 1 1 0 SPT2 chromatin protein UQ_con PF00179.26 KFM67549.1 - 2.6e-44 150.3 0.1 3.3e-44 150.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM67549.1 - 0.027 14.2 0.1 0.11 12.2 0.1 2.0 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 KFM67549.1 - 0.052 13.8 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 RWD domain FERM_C PF09380.10 KFM67550.1 - 1.9e-20 73.1 0.3 4.2e-20 71.9 0.3 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFM67550.1 - 1.2e-15 57.3 3.9 1.2e-15 57.3 3.9 5.4 5 0 0 5 5 5 1 FERM adjacent (FA) FERM_N PF09379.10 KFM67551.1 - 1.5e-16 60.0 0.1 1.7e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 FERM N-terminal domain Ndc1_Nup PF09531.10 KFM67552.1 - 1.7 7.2 5.6 1.9 7.1 5.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_DNAp_acc PF04929.12 KFM67552.1 - 9.9 5.0 13.8 12 4.7 13.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SLC12 PF03522.15 KFM67553.1 - 5.6e-31 108.0 0.8 5.9e-31 107.9 0.8 1.0 1 0 0 1 1 1 1 Solute carrier family 12 SLC12 PF03522.15 KFM67554.1 - 2.2e-20 73.1 0.0 2.4e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 KFM67555.1 - 2.6e-16 59.3 0.2 2.8e-16 59.2 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFM67555.1 - 0.0092 14.8 0.3 0.0094 14.8 0.3 1.0 1 0 0 1 1 1 1 Amino acid permease Dimer_Tnp_hAT PF05699.14 KFM67557.1 - 0.00054 19.7 0.0 0.00086 19.0 0.0 1.4 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_3 PF13358.6 KFM67558.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF1759 PF03564.15 KFM67559.1 - 0.012 15.5 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) RT_RNaseH_2 PF17919.1 KFM67560.1 - 1e-30 105.7 0.0 4.9e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM67560.1 - 2.8e-29 101.5 0.0 1.4e-28 99.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM67560.1 - 2.1e-28 99.4 0.1 5.7e-28 97.9 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM67560.1 - 2e-18 66.7 0.0 3.7e-17 62.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM67560.1 - 2.2e-16 59.7 0.0 7.8e-16 57.9 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Arc_C PF18162.1 KFM67560.1 - 3.8e-05 23.5 1.7 0.00013 21.7 0.4 2.7 3 0 0 3 3 3 1 Arc C-lobe zf-H2C2 PF09337.10 KFM67560.1 - 0.0016 18.6 0.0 0.0041 17.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM67560.1 - 0.021 15.1 2.8 0.23 11.7 0.0 3.8 3 0 0 3 3 3 0 Retrotransposon gag protein AA_permease_N PF08403.10 KFM67561.1 - 1.3e-06 27.8 1.1 2.3e-06 27.0 1.1 1.4 1 0 0 1 1 1 1 Amino acid permease N-terminal COX5A PF02284.16 KFM67562.1 - 1.2e-47 160.1 0.0 1.7e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va TPT PF03151.16 KFM67563.1 - 1.1e-15 57.8 26.7 1.2e-15 57.6 26.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM67563.1 - 0.00031 20.9 36.5 0.00045 20.4 12.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF92 PF01940.16 KFM67563.1 - 0.045 13.2 4.0 0.045 13.2 1.7 2.3 1 1 0 1 1 1 0 Integral membrane protein DUF92 WD40 PF00400.32 KFM67564.1 - 2.4e-17 63.0 4.7 5.3e-05 23.9 0.3 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.11 KFM67564.1 - 2.7e-15 56.0 0.0 4.9e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 KFM67564.1 - 1.1e-07 32.1 0.4 0.00031 21.0 0.2 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFM67564.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Nup160 PF11715.8 KFM67564.1 - 0.13 10.9 0.8 0.43 9.1 0.2 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 WD40_4 PF16300.5 KFM67564.1 - 0.27 11.2 0.7 0.49 10.3 0.7 1.5 1 0 0 1 1 1 0 Type of WD40 repeat WD40_4 PF16300.5 KFM67565.1 - 1.6e-17 63.1 0.4 2.9e-17 62.3 0.4 1.4 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 KFM67565.1 - 3.5e-11 42.8 0.0 6.6e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 KFM67565.1 - 3.7e-08 33.9 1.5 0.011 16.6 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM67565.1 - 6.8e-05 23.1 0.1 0.0029 17.9 0.0 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM67565.1 - 0.0025 17.7 0.0 0.0077 16.1 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KFM67565.1 - 0.12 11.7 0.0 0.98 8.7 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 KFM67566.1 - 0.025 14.9 0.0 4.8 7.6 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KFM67567.1 - 7.1e-13 48.2 0.4 6.6e-11 41.9 0.0 2.6 1 1 1 2 2 2 1 F-box-like F-box PF00646.33 KFM67567.1 - 9.3e-09 35.0 1.4 2.4e-06 27.3 0.0 2.5 3 0 0 3 3 3 2 F-box domain F-box_4 PF15966.5 KFM67567.1 - 4.9e-05 23.2 0.0 0.00017 21.4 0.0 1.8 1 1 1 2 2 2 1 F-box F-box_5 PF18511.1 KFM67567.1 - 7.7e-05 22.2 0.3 0.27 10.8 0.1 3.3 3 0 0 3 3 3 2 F-box Elongin_A PF06881.11 KFM67567.1 - 0.084 13.4 0.1 0.094 13.2 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3173 PF11372.8 KFM67567.1 - 0.1 12.5 0.1 9.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Chorein_N PF12624.7 KFM67568.1 - 6.5e-22 77.8 0.0 8.1e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 KFM67569.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal ATG2_CAD PF13329.6 KFM67570.1 - 4.1e-06 26.6 7.5 7.5e-06 25.7 1.1 3.5 2 1 0 2 2 2 1 Autophagy-related protein 2 CAD motif Kin17_mid PF10357.9 KFM67570.1 - 0.041 13.8 0.3 0.13 12.2 0.3 1.8 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein ATG_C PF09333.11 KFM67571.1 - 2.8e-23 82.1 0.0 8.4e-23 80.5 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 KFM67571.1 - 7.6e-13 48.6 0.1 1.1e-12 48.1 0.1 1.1 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal PDE4_UCR PF18100.1 KFM67573.1 - 8e-50 168.4 1.0 1.2e-49 167.9 0.1 1.7 2 0 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) PDEase_I PF00233.19 KFM67573.1 - 0.0029 17.4 2.1 0.014 15.1 0.2 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 KFM67574.1 - 7.6e-61 205.9 0.6 9e-61 205.6 0.6 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TGF_beta PF00019.20 KFM67575.1 - 2.8e-26 92.5 1.4 5.4e-26 91.6 1.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain zf-CCHC_4 PF14392.6 KFM67576.1 - 0.056 13.2 2.1 0.35 10.6 1.9 2.3 2 0 0 2 2 2 0 Zinc knuckle LemA PF04011.12 KFM67576.1 - 0.16 11.9 2.4 0.52 10.1 0.1 2.5 2 0 0 2 2 2 0 LemA family DDE_1 PF03184.19 KFM67577.1 - 5.8e-11 42.3 0.2 7.1e-11 42.1 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67578.1 - 4.2e-16 58.9 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67578.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67578.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67578.1 - 0.0025 17.6 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67578.1 - 1.7 9.3 15.6 0.12 13.0 1.9 3.3 2 1 1 3 3 3 0 Homeodomain-like domain SBF PF01758.16 KFM67580.1 - 1.1e-24 87.1 11.2 1.1e-24 87.1 11.2 1.6 1 1 0 1 1 1 1 Sodium Bile acid symporter family Mem_trans PF03547.18 KFM67580.1 - 0.15 10.4 7.2 0.23 9.8 2.5 2.7 1 1 1 3 3 3 0 Membrane transport protein Metallophos PF00149.28 KFM67582.1 - 1e-29 104.5 0.1 1.2e-29 104.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KFM67582.1 - 0.0084 15.8 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 KFM67582.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PA-IIL PF07472.11 KFM67583.1 - 0.12 12.7 0.2 6.7 7.1 0.0 3.2 3 0 0 3 3 3 0 Fucose-binding lectin II (PA-IIL) HTH_48 PF17906.1 KFM67584.1 - 9.6e-05 22.4 2.3 0.0006 19.9 0.3 2.3 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_24 PF13412.6 KFM67584.1 - 0.018 14.6 0.1 0.043 13.4 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM67584.1 - 0.084 12.7 0.8 0.24 11.3 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 KFM67584.1 - 0.21 11.5 1.6 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PRK PF00485.18 KFM67585.1 - 8.6e-49 166.0 0.1 1e-48 165.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFM67585.1 - 5.9e-08 33.3 0.0 1.1e-07 32.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 KFM67585.1 - 2.4e-07 30.6 0.3 1e-06 28.6 0.3 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase Zeta_toxin PF06414.12 KFM67585.1 - 0.00035 19.9 0.0 0.00069 18.9 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 KFM67585.1 - 0.00081 19.8 5.1 0.0097 16.3 5.1 2.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFM67585.1 - 0.0066 16.2 0.1 0.62 9.8 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase DUF3019 PF11456.8 KFM67585.1 - 0.018 15.6 0.5 0.029 14.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3019) AAA_33 PF13671.6 KFM67585.1 - 0.042 14.0 0.1 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain FAD_oxidored PF12831.7 KFM67585.1 - 0.052 12.9 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase NB-ARC PF00931.22 KFM67585.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 KFM67585.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AMH_N PF04709.12 KFM67585.1 - 0.25 10.2 0.0 0.43 9.4 0.0 1.3 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region RRM_1 PF00076.22 KFM67586.1 - 1.6e-17 63.1 0.0 3.4e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 KFM67586.1 - 2e-09 37.0 1.7 4.9e-09 35.7 1.7 1.7 1 0 0 1 1 1 1 SAP domain RRM_occluded PF16842.5 KFM67586.1 - 0.0084 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KFM67586.1 - 0.044 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 KFM67587.1 - 1.3e-52 177.1 0.0 1.5e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mis12 PF05859.12 KFM67588.1 - 0.032 14.3 0.1 0.055 13.5 0.1 1.4 1 0 0 1 1 1 0 Mis12 protein tRNA-synt_2d PF01409.20 KFM67589.1 - 5.7e-92 307.6 0.0 8e-92 307.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 KFM67589.1 - 5.1e-19 67.8 0.9 1.1e-18 66.7 0.3 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 KFM67589.1 - 5.2e-18 65.1 0.1 5.2e-18 65.1 0.1 3.0 4 0 0 4 4 4 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 KFM67589.1 - 1.3e-10 41.0 8.4 3.5e-10 39.7 8.4 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 KFM67589.1 - 3.9e-07 29.7 0.0 5.2e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KFM67589.1 - 0.0021 17.2 0.1 0.009 15.1 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF1495 PF07381.11 KFM67589.1 - 0.0067 16.2 0.0 0.1 12.5 0.0 2.5 1 1 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) tRNA-synt_2b PF00587.25 KFM67589.1 - 0.0089 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HBS1_N PF08938.10 KFM67590.1 - 2.1e-05 24.7 0.0 5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 HBS1 N-terminus Phage_tail_APC PF16778.5 KFM67590.1 - 0.06 13.2 0.1 0.25 11.2 0.0 2.0 2 1 0 2 2 2 0 Phage tail assembly chaperone protein BTB PF00651.31 KFM67593.1 - 0.0077 16.5 0.0 0.27 11.5 0.0 2.3 1 1 0 1 1 1 1 BTB/POZ domain PP1c_bdg PF10488.9 KFM67593.1 - 0.081 12.4 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region NUDE_C PF04880.13 KFM67595.1 - 3.1e-31 109.2 9.7 3.1e-31 109.2 9.7 2.3 2 0 0 2 2 1 1 NUDE protein, C-terminal conserved region Golgin_A5 PF09787.9 KFM67595.1 - 0.05 13.1 37.1 0.13 11.7 17.2 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Lip_prot_lig_C PF10437.9 KFM67595.1 - 0.055 13.5 1.7 6.2 6.9 0.2 3.5 2 1 1 3 3 3 0 Bacterial lipoate protein ligase C-terminus DUF4407 PF14362.6 KFM67595.1 - 0.54 9.6 18.2 0.21 10.9 15.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 KFM67595.1 - 0.77 9.8 36.1 0.33 11.0 24.7 3.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KFM67595.1 - 1 9.8 34.6 0.18 12.3 19.2 2.9 1 1 1 2 2 2 0 Fez1 SLATT_fungal PF18142.1 KFM67595.1 - 2.7 8.0 7.7 0.64 10.0 0.9 2.6 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain HeLo PF14479.6 KFM67595.1 - 2.8 7.7 13.9 1.2 8.9 11.0 1.9 1 1 1 2 2 2 0 Prion-inhibition and propagation Baculo_PEP_C PF04513.12 KFM67595.1 - 3.3 7.8 11.9 13 5.8 4.7 2.9 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Plasmid_RAQPRD PF09686.10 KFM67595.1 - 3.9 7.8 8.9 0.4 10.9 1.3 2.9 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Retrotrans_gag PF03732.17 KFM67595.1 - 4.7 7.5 9.0 1.5 9.2 3.8 2.6 1 1 1 2 2 2 0 Retrotransposon gag protein ERM PF00769.19 KFM67595.1 - 5.4 6.8 36.9 2.4e+02 1.4 36.9 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family PRKG1_interact PF15898.5 KFM67595.1 - 6.9 7.6 38.3 0.071 14.0 16.3 3.6 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain GAS PF13851.6 KFM67595.1 - 7.6 5.8 33.1 2.3 7.5 24.4 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prominin PF05478.11 KFM67595.1 - 9.6 4.0 15.5 11 3.8 14.3 1.6 1 1 0 1 1 1 0 Prominin Lig_chan-Glu_bd PF10613.9 KFM67599.1 - 2.5e-07 30.9 0.0 2.9e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lipase_3 PF01764.25 KFM67601.1 - 8.4e-14 51.6 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KFM67601.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Sigma_reg_N PF13800.6 KFM67601.1 - 0.99 9.7 3.1 4.4 7.7 0.5 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal L51_S25_CI-B8 PF05047.16 KFM67602.1 - 9.1e-13 47.9 0.0 1.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RapA_C PF12137.8 KFM67602.1 - 0.13 11.2 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Lipase_3 PF01764.25 KFM67603.1 - 2.8e-13 49.9 0.0 6.1e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Forkhead PF00250.18 KFM67604.1 - 3.5e-40 136.2 0.3 6.2e-40 135.3 0.3 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KFM67604.1 - 2.1e-08 34.4 0.3 5.9e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 FHA domain Linker_histone PF00538.19 KFM67604.1 - 0.17 12.2 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family Chromo PF00385.24 KFM67605.1 - 4.4e-14 52.1 0.5 4.4e-14 52.1 0.5 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 KFM67605.1 - 1.3e-13 50.4 2.6 3.4e-13 49.1 2.6 1.8 1 0 0 1 1 1 1 CBX family C-terminal motif Tudor-knot PF11717.8 KFM67605.1 - 0.00011 22.0 0.4 0.00022 21.0 0.4 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.6 KFM67605.1 - 0.099 12.8 0.3 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Lipase_3 PF01764.25 KFM67606.1 - 6.1e-18 65.0 0.0 9.9e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KFM67606.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM67606.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-H2C2_2 PF13465.6 KFM67607.1 - 2.4e-100 324.9 102.5 2.8e-08 33.8 0.4 15.1 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67607.1 - 4.6e-67 218.9 118.5 1e-05 25.7 3.1 14.2 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67607.1 - 5.2e-48 157.5 109.8 0.00072 20.2 1.3 14.2 14 0 0 14 14 14 13 C2H2-type zinc finger zf-met PF12874.7 KFM67607.1 - 2.9e-31 106.9 100.0 0.0038 17.6 2.3 13.6 13 0 0 13 13 13 13 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM67607.1 - 8.3e-21 73.7 69.4 0.0052 17.0 0.3 13.7 12 1 1 13 13 13 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM67607.1 - 1.2e-18 66.6 89.8 0.0085 16.1 1.1 13.4 13 0 0 13 13 13 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM67607.1 - 7.2e-15 54.4 77.9 0.36 10.6 0.2 14.3 14 0 0 14 14 14 8 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM67607.1 - 1.2e-13 50.6 73.0 0.0087 15.8 0.2 13.2 14 0 0 14 14 14 8 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM67607.1 - 5.3e-09 35.7 47.8 2.8 7.9 0.1 13.0 12 1 1 13 13 13 2 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM67607.1 - 9.9e-06 25.6 53.2 5.7 7.1 0.1 11.8 12 0 0 12 12 11 1 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM67607.1 - 3.2e-05 24.0 52.6 0.038 14.1 5.2 5.5 1 1 4 5 5 5 4 Putative ribonucleoprotein zinc-finger pf C4 type Tox-HNH-HHH PF15637.6 KFM67607.1 - 3.5e-05 23.9 12.1 4.4 7.5 0.0 6.5 1 1 7 8 8 8 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif ADK_lid PF05191.14 KFM67607.1 - 0.0001 22.2 38.4 0.86 9.6 1.2 8.4 1 1 9 11 11 11 4 Adenylate kinase, active site lid FYVE PF01363.21 KFM67607.1 - 0.00015 21.8 67.4 1.8 8.7 8.4 7.7 1 1 4 5 5 5 1 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 KFM67607.1 - 0.00055 19.9 59.6 0.67 10.0 1.0 12.8 8 2 5 13 13 13 2 Sec23/Sec24 zinc finger DUF3338 PF11819.8 KFM67607.1 - 0.0044 17.0 0.0 26 4.8 0.0 4.8 2 2 3 5 5 5 0 Domain of unknown function (DUF3338) DUF2256 PF10013.9 KFM67607.1 - 0.017 15.2 43.2 28 4.9 0.0 12.7 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Dof PF02701.15 KFM67607.1 - 0.068 13.3 34.5 0.09 12.9 0.1 9.2 1 1 7 9 9 9 0 Dof domain, zinc finger zf-C2H2_9 PF16293.5 KFM67607.1 - 0.071 13.0 57.7 4.3 7.3 0.3 12.6 1 1 12 13 13 13 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM67607.1 - 0.17 11.7 31.1 3 7.7 0.1 9.7 2 1 11 13 13 13 0 GAGA factor C1_1 PF00130.22 KFM67607.1 - 0.19 11.6 77.6 1.6 8.7 0.6 12.6 5 2 5 11 11 11 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PqqA PF08042.11 KFM67607.1 - 0.21 11.7 9.4 5.4e+02 0.9 0.0 8.5 11 0 0 11 11 11 0 PqqA family zf_UBZ PF18439.1 KFM67607.1 - 1.1 8.8 58.7 11 5.7 0.3 12.6 13 0 0 13 13 13 0 Ubiquitin-Binding Zinc Finger DUF960 PF06124.11 KFM67607.1 - 1.3 9.7 4.0 1.8e+02 2.9 0.0 4.5 3 2 3 6 6 6 0 Staphylococcal protein of unknown function (DUF960) MCR_D PF02505.14 KFM67607.1 - 1.4 8.7 3.5 29 4.5 0.1 4.5 2 2 4 6 6 6 0 Methyl-coenzyme M reductase operon protein D DUF952 PF06108.12 KFM67607.1 - 2.6 8.1 5.4 34 4.5 0.1 4.4 3 1 2 6 6 5 0 Protein of unknown function (DUF952) zinc_ribbon_15 PF17032.5 KFM67607.1 - 7.7 7.3 53.4 3.1 8.6 1.5 7.0 1 1 7 9 9 9 0 zinc-ribbon family DDE_3 PF13358.6 KFM67608.1 - 1.4e-09 37.8 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PPO1_DWL PF12142.8 KFM67608.1 - 0.074 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Polyphenol oxidase middle domain SAB PF04382.13 KFM67608.1 - 0.14 12.2 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 SAB domain DDE_Tnp_4 PF13359.6 KFM67610.1 - 2.7e-20 72.6 0.0 3.1e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KFM67610.1 - 2.1e-06 27.5 0.0 2.4e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 KFM67610.1 - 0.0059 16.2 0.0 0.0071 16.0 0.0 1.0 1 0 0 1 1 1 1 Plant transposon protein PH PF00169.29 KFM67611.1 - 2.3e-09 37.7 0.6 3.3e-09 37.2 0.6 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM67611.1 - 0.0026 18.1 0.5 0.006 17.0 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain IRS PF02174.17 KFM67611.1 - 0.0099 15.7 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) DUF3788 PF12663.7 KFM67611.1 - 0.048 13.6 0.8 1.8 8.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3788) rve PF00665.26 KFM67612.1 - 5.3e-10 39.5 0.0 1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Peptidase_C1 PF00112.23 KFM67613.1 - 9.3e-75 251.5 2.6 9.3e-75 251.5 2.6 2.1 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM67613.1 - 6e-13 49.0 2.6 1.2e-12 48.0 2.6 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Cystatin PF00031.21 KFM67613.1 - 3.9e-10 39.9 1.8 1e-09 38.5 1.8 1.7 1 0 0 1 1 1 1 Cystatin domain Peptidase_C1_2 PF03051.15 KFM67613.1 - 0.00038 19.4 0.1 0.14 10.9 0.0 2.5 2 0 0 2 2 2 2 Peptidase C1-like family SQAPI PF16845.5 KFM67613.1 - 0.016 15.5 1.5 0.042 14.2 0.3 2.1 1 1 1 2 2 2 0 Aspartic acid proteinase inhibitor Mitochondr_Som1 PF11093.8 KFM67613.1 - 0.13 12.2 1.1 0.33 11.0 1.1 1.6 1 0 0 1 1 1 0 Mitochondrial export protein Som1 ZFYVE21_C PF16696.5 KFM67614.1 - 8.2e-25 87.1 0.0 1e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Zinc finger FYVE domain-containing protein 21 C-terminus Phage_T7_tail PF03906.14 KFM67614.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage T7 tail fibre protein rve PF00665.26 KFM67615.1 - 0.0012 19.0 0.1 0.0041 17.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_1_7 PF13843.6 KFM67616.1 - 2e-37 129.3 0.1 2.7e-37 128.9 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 Binary_toxB_3 PF17476.2 KFM67616.1 - 0.021 15.0 0.2 0.054 13.7 0.2 1.7 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 3 DDE_Tnp_1 PF01609.21 KFM67616.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 Transposase DDE domain DDE_3 PF13358.6 KFM67617.1 - 2.7e-16 59.6 0.1 3e-15 56.3 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67617.1 - 1.4e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67618.1 - 5.9e-16 58.5 0.1 6.8e-15 55.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67618.1 - 7.6e-16 58.1 6.5 1.6e-15 57.1 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM67618.1 - 0.00081 20.0 1.5 0.00081 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67618.1 - 0.0025 17.6 0.1 0.099 12.5 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67618.1 - 0.018 15.1 0.1 0.072 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM67618.1 - 0.027 14.5 2.1 0.035 14.1 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM67618.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase LRR_8 PF13855.6 KFM67619.1 - 7.8e-77 253.0 88.3 1.7e-15 56.5 6.3 5.8 2 1 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFM67619.1 - 5.9e-31 107.1 20.9 9.8e-13 48.2 0.4 3.3 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM67619.1 - 2.2e-30 104.2 53.3 2.7e-06 27.6 3.2 7.4 4 2 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM67619.1 - 1e-10 41.4 29.6 9.9e-05 21.9 1.6 4.9 1 1 5 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 KFM67619.1 - 5.7e-06 26.2 45.9 2.1 9.2 0.1 11.2 10 2 0 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.6 KFM67619.1 - 0.00084 19.2 40.5 2.4 8.4 0.0 10.0 11 0 0 11 11 11 5 Leucine Rich repeat Zein PF01559.16 KFM67619.1 - 0.016 14.8 2.4 0.027 14.1 2.4 1.4 1 1 0 1 1 1 0 Zein seed storage protein LRR_12 PF18837.1 KFM67619.1 - 7 6.4 16.7 8.7 6.1 0.4 5.3 4 1 1 5 5 5 0 Leucine-rich repeat LRR_8 PF13855.6 KFM67620.1 - 7.5e-14 51.2 12.5 4.5e-07 29.5 1.2 2.0 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM67620.1 - 2.8e-10 40.3 10.3 2.1e-05 24.8 2.1 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM67620.1 - 3.7e-05 23.7 9.0 0.023 15.2 1.5 3.6 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 KFM67620.1 - 0.00054 19.8 0.6 0.00054 19.8 0.6 3.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_5 PF13306.6 KFM67620.1 - 0.0011 18.9 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 KFM67621.1 - 3.2e-54 180.5 60.9 1.1e-15 57.1 3.4 7.3 2 2 4 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFM67621.1 - 2.2e-20 72.9 5.9 2.5e-09 37.2 0.8 3.2 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM67621.1 - 2.1e-19 69.3 51.2 0.00014 22.1 3.6 7.8 4 2 5 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM67621.1 - 8.6e-08 31.7 41.6 0.17 12.6 0.4 11.3 10 2 0 10 10 10 4 Leucine Rich Repeat fn3 PF00041.21 KFM67621.1 - 1.2e-06 28.8 0.3 3.1e-06 27.4 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III domain LRR_9 PF14580.6 KFM67621.1 - 6.9e-06 25.7 16.2 0.0046 16.5 1.5 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KFM67621.1 - 0.002 18.0 51.6 0.34 11.1 0.1 11.3 12 0 0 12 12 12 4 Leucine Rich repeat stn_TNFRSF12A PF12191.8 KFM67621.1 - 0.012 15.8 0.1 0.89 9.8 0.0 2.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain LRRCT PF01463.24 KFM67621.1 - 0.057 14.0 1.8 0.1 13.2 0.2 2.4 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain DDE_3 PF13358.6 KFM67623.1 - 7.2e-11 42.0 0.0 9.8e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease OxoDH_E1alpha_N PF12573.8 KFM67624.1 - 2 8.2 18.0 4.3 7.2 0.4 5.7 5 0 0 5 5 5 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Sds3 PF08598.11 KFM67625.1 - 6.2e-20 72.2 21.1 6.2e-20 72.2 21.1 1.5 1 1 0 1 1 1 1 Sds3-like CAMSAP_CC1 PF17095.5 KFM67625.1 - 0.037 13.9 3.1 0.037 13.9 3.1 2.6 2 1 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin WD40 PF00400.32 KFM67626.1 - 8.8e-18 64.4 20.3 2.3e-09 37.7 0.2 5.5 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM67626.1 - 8.3e-05 22.8 0.0 0.016 15.5 0.0 3.6 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PSI PF01437.25 KFM67627.1 - 2.5e-05 24.7 12.4 4.6e-05 23.9 12.4 1.4 1 0 0 1 1 1 1 Plexin repeat Na_sulph_symp PF00939.19 KFM67628.1 - 3.6e-75 253.8 20.4 4.1e-75 253.6 20.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFM67628.1 - 5.3e-39 134.2 46.0 1.2e-19 70.7 8.3 3.0 2 1 1 3 3 3 3 Citrate transporter ABC_tran PF00005.27 KFM67629.1 - 1.3e-20 74.3 0.0 2.6e-20 73.3 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFM67629.1 - 7e-05 22.8 0.0 0.00072 19.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Apocytochr_F_N PF16639.5 KFM67630.1 - 0.083 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Apocytochrome F, N-terminal 7tm_2 PF00002.24 KFM67631.1 - 1.2e-08 34.5 0.1 1.3e-08 34.4 0.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ldl_recept_a PF00057.18 KFM67633.1 - 9.5e-09 35.3 12.4 2.4e-08 34.0 12.4 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFM67633.1 - 8.8e-05 22.8 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 CUB domain EphA2_TM PF14575.6 KFM67633.1 - 0.039 14.8 0.0 0.082 13.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 KFM67633.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 2 0 0 2 2 2 0 Glycophorin A MitMem_reg PF13012.6 KFM67634.1 - 2.6e-36 124.4 0.6 4.7e-36 123.6 0.6 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFM67634.1 - 7.5e-34 116.2 0.2 2.3e-33 114.6 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Connexin PF00029.19 KFM67634.1 - 0.25 11.1 0.5 0.37 10.5 0.5 1.3 1 0 0 1 1 1 0 Connexin TPR_17 PF13431.6 KFM67635.1 - 0.0014 18.8 0.1 0.0067 16.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM67635.1 - 0.0022 17.7 0.0 0.14 11.8 0.0 3.1 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 KFM67635.1 - 0.012 15.9 0.5 0.18 12.0 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFM67635.1 - 0.014 15.5 6.2 2.6 8.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM67635.1 - 0.037 14.7 0.4 8.6 7.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM67635.1 - 0.064 14.1 1.8 32 5.7 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM67635.1 - 0.068 13.7 0.3 58 4.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM67635.1 - 0.13 12.1 2.9 12 6.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM67636.1 - 5.2e-05 23.6 0.8 0.0019 18.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM67636.1 - 0.0042 16.9 0.1 0.0073 16.1 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM67636.1 - 0.0055 17.2 1.4 0.017 15.6 0.3 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM67636.1 - 0.006 16.7 1.8 0.0061 16.7 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM67636.1 - 0.009 16.1 1.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM67636.1 - 0.015 15.5 0.2 0.018 15.3 0.2 1.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFM67636.1 - 0.02 15.1 0.3 0.078 13.3 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM67636.1 - 0.073 13.1 0.1 0.14 12.3 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Beach PF02138.18 KFM67637.1 - 4.7e-108 360.8 2.1 9e-108 359.8 2.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KFM67637.1 - 4.6e-12 45.9 0.1 1.8e-11 44.0 0.1 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFM67637.1 - 0.00039 21.2 1.8 2.4 9.2 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF3361 PF11841.8 KFM67637.1 - 0.49 10.3 8.2 0.47 10.4 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Laminin_G_3 PF13385.6 KFM67638.1 - 0.0085 16.3 2.5 0.23 11.6 2.5 2.1 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily E3_UbLigase_R4 PF13764.6 KFM67639.1 - 0.014 13.6 0.1 0.014 13.6 0.1 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 RSN1_TM PF13967.6 KFM67640.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.0 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport RseA_C PF03873.13 KFM67642.1 - 0.068 13.4 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain MRP-L46 PF11788.8 KFM67643.1 - 8.7e-15 55.5 0.6 1.7e-14 54.6 0.6 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KFM67643.1 - 0.022 14.8 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 NUDIX domain Glycoprotein_B PF00606.18 KFM67643.1 - 0.066 12.6 0.1 7 6.0 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B ectodomain Glyco_transf_90 PF05686.12 KFM67645.1 - 6.3e-93 311.8 2.3 8.1e-93 311.4 2.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.19 KFM67645.1 - 9.8e-05 23.1 0.0 0.00019 22.2 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Glyco_trans_1_2 PF13524.6 KFM67645.1 - 0.0019 18.6 0.0 0.0045 17.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Integrase_H2C2 PF17921.1 KFM67646.1 - 7.5e-11 42.0 0.4 9.3e-11 41.7 0.4 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM67646.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 H2C2 zinc finger DUF5000 PF16391.5 KFM67649.1 - 0.0025 18.0 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function HTH_32 PF13565.6 KFM67649.1 - 0.032 14.8 1.9 0.061 13.9 1.9 1.5 1 1 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.6 KFM67651.1 - 5.8e-16 58.6 0.1 5.4e-15 55.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67651.1 - 1.8e-10 40.9 1.0 3.8e-10 39.8 1.0 1.6 1 0 0 1 1 1 1 Transposase Mob1_phocein PF03637.17 KFM67652.1 - 3.4e-59 199.6 1.0 5.5e-59 199.0 1.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family PAP1 PF08601.10 KFM67652.1 - 0.4 10.4 7.9 0.56 9.9 7.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Fer4_20 PF14691.6 KFM67654.1 - 0.014 15.2 1.8 0.016 15.0 1.8 1.1 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster RT_RNaseH_2 PF17919.1 KFM67655.1 - 6.1e-31 106.4 0.0 1.7e-30 105.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM67655.1 - 3.6e-28 98.6 1.2 7.5e-28 97.6 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM67655.1 - 4.9e-28 97.5 0.0 1.5e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM67655.1 - 7.8e-20 70.7 0.2 2.9e-19 68.9 0.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM67655.1 - 6.5e-18 65.0 0.0 1.7e-15 57.2 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KFM67655.1 - 2.8e-09 37.4 0.0 9.2e-09 35.8 0.0 2.0 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM67655.1 - 1.5e-05 25.6 0.0 3.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM67655.1 - 1.7e-05 25.0 0.0 4.9e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KFM67655.1 - 5.2e-05 23.4 1.0 0.00013 22.1 1.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KFM67655.1 - 8.3e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Arc_C PF18162.1 KFM67655.1 - 0.00017 21.4 3.1 0.00018 21.3 0.6 2.3 2 0 0 2 2 2 1 Arc C-lobe RVT_3 PF13456.6 KFM67655.1 - 0.0026 17.6 0.1 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Asp_protease PF09668.10 KFM67655.1 - 0.0033 17.2 0.1 0.0074 16.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease BH4 PF02180.17 KFM67655.1 - 0.06 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 CBM_14 PF01607.24 KFM67657.1 - 1.3e-11 44.5 5.7 1.3e-11 44.5 5.7 1.9 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain DivIC PF04977.15 KFM67661.1 - 0.017 14.9 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Trimer_CC PF08954.11 KFM67661.1 - 0.071 12.7 1.4 0.23 11.1 1.4 1.8 1 0 0 1 1 1 0 Trimerisation motif HTH_Tnp_Tc3_2 PF01498.18 KFM67662.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67662.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67662.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67662.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67662.1 - 2.1 9.0 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Mito_carr PF00153.27 KFM67663.1 - 2e-53 178.3 2.0 1.2e-22 79.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM67663.1 - 0.15 11.2 1.3 1.5 7.9 0.0 2.9 3 1 1 4 4 4 0 Gammaproteobacterial serine protease HMG_box PF00505.19 KFM67664.1 - 8e-22 77.4 20.4 3.4e-14 53.0 0.6 3.4 2 2 1 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM67664.1 - 2.6e-15 56.7 18.3 5.5e-10 39.7 6.7 3.1 2 1 1 3 3 3 2 HMG-box domain Protamine_like PF06382.11 KFM67664.1 - 6.2e-06 26.5 8.2 0.0055 16.9 4.5 2.2 1 1 1 2 2 2 2 Protamine and protamine like NPA PF16469.5 KFM67664.1 - 0.062 13.9 10.6 0.02 15.5 7.2 1.9 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 Gp-FAR-1 PF05823.12 KFM67664.1 - 0.064 13.6 6.1 3 8.2 0.2 2.7 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) LTXXQ PF07813.12 KFM67664.1 - 0.29 11.9 0.1 0.29 11.9 0.1 2.8 1 1 1 2 2 2 0 LTXXQ motif family protein GAPT PF11770.8 KFM67664.1 - 0.44 10.4 4.6 5.9 6.7 0.3 2.1 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) FTA4 PF13093.6 KFM67664.1 - 0.61 9.9 13.0 0.8 9.6 12.7 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1104 PF06518.11 KFM67664.1 - 0.68 10.3 13.2 3.5 8.1 3.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1104) Syntaxin_2 PF14523.6 KFM67664.1 - 1.1 9.7 5.3 4 7.9 1.3 2.2 2 0 0 2 2 2 0 Syntaxin-like protein PhzC-PhzF PF02567.16 KFM67665.1 - 5.1e-54 183.7 0.0 6.3e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein PhzC-PhzF PF02567.16 KFM67666.1 - 9e-49 166.4 0.0 1.6e-48 165.6 0.0 1.4 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein HTH_48 PF17906.1 KFM67667.1 - 8.8e-05 22.6 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HRM PF02793.22 KFM67668.1 - 4.8e-18 65.2 8.0 4.8e-18 65.2 8.0 1.5 2 0 0 2 2 2 1 Hormone receptor domain 7tm_2 PF00002.24 KFM67668.1 - 1.5e-09 37.5 1.2 2.1e-09 37.0 1.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.24 KFM67669.1 - 5.6e-21 74.9 0.9 6.1e-21 74.8 0.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) RVT_1 PF00078.27 KFM67671.1 - 0.018 14.6 0.0 0.018 14.5 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4988 PF16378.5 KFM67671.1 - 0.24 11.0 0.2 0.32 10.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function Neur_chan_LBD PF02931.23 KFM67672.1 - 1.5e-42 145.5 0.3 2.1e-42 145.1 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM67672.1 - 1.1e-11 45.2 8.4 3.1e-09 37.2 4.0 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HTH_Tnp_Tc3_2 PF01498.18 KFM67673.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67673.1 - 2e-13 50.3 0.0 3.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Dynactin PF12455.8 KFM67674.1 - 4.2e-81 272.3 7.2 4.2e-81 272.3 7.2 4.0 1 1 2 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 KFM67674.1 - 2.5e-21 75.5 1.7 4.3e-21 74.7 1.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain Atg14 PF10186.9 KFM67674.1 - 0.00039 19.6 7.6 0.00039 19.6 7.6 3.4 1 1 1 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 Pox_A_type_inc PF04508.12 KFM67674.1 - 0.059 13.3 4.7 5.5 7.0 0.3 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Filament PF00038.21 KFM67674.1 - 0.55 9.8 73.3 0.042 13.4 13.1 4.5 2 2 2 4 4 4 0 Intermediate filament protein VPS11_C PF12451.8 KFM67674.1 - 6.1 7.2 12.0 7.2 6.9 2.8 4.0 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal Shugoshin_N PF07558.11 KFM67675.1 - 0.0011 18.8 8.6 0.0029 17.4 1.1 3.4 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region MbeD_MobD PF04899.12 KFM67675.1 - 0.019 15.0 4.0 6.8 6.9 1.7 3.7 3 1 0 3 3 3 0 MbeD/MobD like Osmo_CC PF08946.10 KFM67675.1 - 0.23 11.7 8.2 0.18 12.1 4.5 2.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil ATG16 PF08614.11 KFM67675.1 - 0.33 11.1 26.0 2.6 8.2 10.6 4.3 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 KFM67675.1 - 0.75 7.2 17.7 0.074 10.6 12.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) GIT_CC PF16559.5 KFM67675.1 - 0.97 9.3 20.4 2.5 8.1 2.0 4.5 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.18 KFM67675.1 - 1.1 9.5 14.8 3.1 8.1 0.4 4.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper UPF0242 PF06785.11 KFM67675.1 - 2.8 8.0 25.3 0.47 10.5 14.5 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 KFM67675.1 - 5.3 7.1 17.8 11 6.1 0.3 4.2 3 1 0 3 3 3 0 FlxA-like protein Asparaginase_2 PF01112.18 KFM67676.1 - 9e-102 340.2 9.8 1.1e-101 339.9 9.8 1.0 1 0 0 1 1 1 1 Asparaginase Polyoma_coat PF00718.20 KFM67676.1 - 0.089 12.1 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein OmpA PF00691.20 KFM67677.1 - 0.033 14.6 0.1 0.035 14.5 0.1 1.1 1 0 0 1 1 1 0 OmpA family MFS_2 PF13347.6 KFM67678.1 - 2.9e-05 22.8 0.4 4.4e-05 22.2 0.4 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KFM67678.1 - 0.011 14.7 1.6 0.017 14.0 1.1 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily MFS_1_like PF12832.7 KFM67678.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 MFS_1 like family FMN_dh PF01070.18 KFM67679.1 - 1.1e-49 169.4 0.6 1.2e-49 169.3 0.6 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFM67679.1 - 2.6e-07 30.0 1.0 1.7e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFM67679.1 - 5e-05 22.6 0.0 6.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KFM67679.1 - 0.03 13.5 1.2 1.5 8.0 0.1 2.2 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase NMO PF03060.15 KFM67679.1 - 0.068 12.5 0.3 0.09 12.1 0.3 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase BPD_transp_1 PF00528.22 KFM67679.1 - 0.096 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component HTH_Tnp_Tc3_2 PF01498.18 KFM67680.1 - 2.7e-16 59.6 2.8 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67680.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67680.1 - 2.1e-09 37.0 1.5 6.3e-09 35.5 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67680.1 - 0.0017 18.1 0.7 0.0049 16.6 0.7 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67680.1 - 0.015 15.4 0.4 0.046 13.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2285 PF10074.9 KFM67680.1 - 0.076 13.7 1.3 0.076 13.7 1.3 2.7 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2285) HTH_32 PF13565.6 KFM67680.1 - 0.11 13.1 17.0 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Asp PF00026.23 KFM67682.1 - 1.2e-119 399.4 0.0 1.4e-119 399.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFM67682.1 - 3.2e-17 63.3 1.9 1.7e-15 57.7 1.9 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFM67682.1 - 0.021 14.7 0.3 0.038 13.9 0.3 1.4 1 0 0 1 1 1 0 A1 Propeptide Phage_SSB PF16773.5 KFM67682.1 - 0.15 12.1 0.1 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Lactococcus phage single-stranded DNA binding protein UBA PF00627.31 KFM67683.1 - 1.3e-05 24.9 0.6 0.17 11.8 0.0 3.3 2 1 1 3 3 3 2 UBA/TS-N domain UBA_3 PF09288.10 KFM67683.1 - 0.00081 19.1 1.0 0.76 9.6 0.1 2.8 2 1 0 2 2 2 2 Fungal ubiquitin-associated domain WIYLD PF10440.9 KFM67683.1 - 0.03 14.1 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF1421 PF07223.11 KFM67683.1 - 0.042 13.7 0.2 0.32 10.9 0.2 2.2 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Thioredoxin_13 PF18401.1 KFM67683.1 - 0.072 13.0 0.0 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Sugar_tr PF00083.24 KFM67684.1 - 3.8e-33 115.0 19.0 5.2e-33 114.6 19.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM67684.1 - 4.7e-31 108.0 51.1 2.2e-27 95.9 30.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily HLH PF00010.26 KFM67685.1 - 5.8e-20 71.0 0.1 5.8e-20 71.0 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM67686.1 - 2.7e-16 59.6 0.5 4.8e-16 58.8 0.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM67686.1 - 2.3e-05 24.9 3.8 0.00029 21.4 0.8 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67686.1 - 0.011 15.5 1.3 0.37 10.6 0.1 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM67686.1 - 0.055 13.5 0.8 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_3 PF01381.22 KFM67686.1 - 0.065 13.3 0.1 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix HTH_28 PF13518.6 KFM67686.1 - 0.13 12.4 4.3 0.59 10.3 0.2 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KFM67686.1 - 0.17 11.5 0.1 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sod_Fe_N PF00081.22 KFM67687.1 - 2.9e-15 56.5 1.3 4.7e-15 55.8 1.3 1.3 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Tom22 PF04281.13 KFM67688.1 - 5.1e-13 49.0 0.9 6.6e-13 48.6 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CN_hydrolase PF00795.22 KFM67689.1 - 4.6e-18 65.5 0.0 7.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DDE_3 PF13358.6 KFM67690.1 - 3.2e-10 39.9 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Galactosyl_T PF01762.21 KFM67692.1 - 1.9e-33 115.9 0.0 2.4e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFM67692.1 - 0.01 15.3 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 0 Fringe-like bZIP_2 PF07716.15 KFM67693.1 - 9.2e-08 32.0 11.5 1.7e-07 31.2 11.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM67693.1 - 0.0097 16.0 8.4 0.02 14.9 8.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor RT_RNaseH_2 PF17919.1 KFM67695.1 - 1.2e-07 31.7 0.0 1.3e-07 31.6 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM67695.1 - 4.6e-06 26.9 0.0 4.9e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RcsD_ABL PF16359.5 KFM67696.1 - 3e-09 36.9 0.9 18 5.5 0.0 6.4 6 0 0 6 6 6 5 RcsD-ABL domain Herpes_glycoH_C PF17488.2 KFM67696.1 - 3.3e-05 23.7 0.0 26 4.6 0.0 5.4 1 1 5 6 6 6 2 Herpesvirus glycoprotein H C-terminal domain DNA_ligase_ZBD PF03119.16 KFM67696.1 - 0.0039 17.2 7.4 93 3.2 0.0 6.2 7 0 0 7 7 7 0 NAD-dependent DNA ligase C4 zinc finger domain DUF1907 PF08925.11 KFM67696.1 - 0.008 15.7 15.5 5.9 6.2 0.1 5.8 1 1 5 6 6 6 1 Domain of Unknown Function (DUF1907) IGR PF09597.10 KFM67696.1 - 0.011 15.8 17.0 58 3.9 0.1 6.2 6 0 0 6 6 6 0 IGR protein motif Lebercilin PF15619.6 KFM67697.1 - 0.00057 19.6 38.8 0.00057 19.6 38.8 6.1 3 3 1 5 5 5 2 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 KFM67697.1 - 0.0053 16.1 38.9 0.0053 16.1 38.9 6.3 4 1 3 7 7 7 4 Growth-arrest specific micro-tubule binding WHEP-TRS PF00458.20 KFM67697.1 - 0.76 10.0 7.7 3.9 7.7 0.1 4.0 3 1 0 3 3 3 0 WHEP-TRS domain SAM_1 PF00536.30 KFM67698.1 - 6.6e-25 87.3 1.2 5.1e-13 49.2 0.2 3.4 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM67698.1 - 2e-24 85.5 0.4 9.9e-10 38.4 0.0 3.5 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) TSGP1 PF07771.11 KFM67699.1 - 0.017 15.3 2.1 0.02 15.1 2.1 1.2 1 1 0 1 1 1 0 Tick salivary peptide group 1 Stomagen PF16851.5 KFM67699.1 - 0.038 14.0 2.4 0.054 13.5 1.3 1.8 1 1 1 2 2 2 0 Stomagen Ank_4 PF13637.6 KFM67700.1 - 1.3e-27 95.8 4.3 5.1e-13 49.2 0.1 3.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM67700.1 - 1e-26 93.3 0.1 4.9e-15 55.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFM67700.1 - 1.8e-20 72.4 2.0 3e-08 33.8 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFM67700.1 - 1.9e-17 61.6 0.3 3.7e-05 23.8 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFM67700.1 - 6.6e-17 61.4 0.3 3.1e-06 27.3 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Cwf_Cwc_15 PF04889.12 KFM67700.1 - 0.092 12.5 0.2 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein EGF_3 PF12947.7 KFM67701.1 - 0.19 12.0 6.4 0.39 10.9 6.4 1.6 1 0 0 1 1 1 0 EGF domain TIL PF01826.17 KFM67701.1 - 0.76 10.1 6.9 1.4 9.2 6.2 1.9 2 1 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain RTP1_C1 PF10363.9 KFM67702.1 - 0.044 14.0 0.1 0.044 14.0 0.1 1.0 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-C2H2 PF00096.26 KFM67703.1 - 4.6e-14 52.0 28.3 2.4e-05 24.5 0.5 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM67703.1 - 7.6e-12 45.1 7.7 1.2e-07 31.8 1.1 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM67703.1 - 1.5e-08 34.8 21.8 0.0013 19.4 2.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFM67703.1 - 0.011 16.3 7.7 0.81 10.4 0.4 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFM67703.1 - 0.59 10.5 10.6 0.19 12.0 5.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc ribbon zf-met PF12874.7 KFM67703.1 - 1.2 9.7 9.0 4.8 7.7 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KFM67703.1 - 3 8.6 6.7 2.5 8.8 3.0 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM67704.1 - 4.6e-08 33.2 0.2 7.3e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67704.1 - 0.003 17.3 0.0 0.07 12.9 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67705.1 - 2.1e-16 59.9 2.2 3.9e-16 59.1 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67705.1 - 4e-13 49.4 0.0 6.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67706.1 - 4.6e-16 58.8 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67706.1 - 1.2e-13 51.1 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67706.1 - 1.9e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67706.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67706.1 - 1.9 9.2 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM67707.1 - 6.8e-09 35.6 0.1 1.1e-08 35.0 0.1 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease LisH PF08513.11 KFM67708.1 - 0.0038 17.1 0.1 0.0038 17.1 0.1 2.8 3 0 0 3 3 3 1 LisH Glycophorin_A PF01102.18 KFM67709.1 - 0.0024 18.1 1.7 0.11 12.7 1.7 2.7 1 1 0 1 1 1 1 Glycophorin A Na_H_antiporter PF03553.14 KFM67709.1 - 0.019 14.2 0.4 0.026 13.7 0.4 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter family DUF1180 PF06679.12 KFM67709.1 - 0.15 12.5 9.5 0.039 14.4 2.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) DUF3188 PF11384.8 KFM67709.1 - 3 7.6 5.6 2.8 7.7 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) DUF4282 PF14110.6 KFM67710.1 - 0.019 15.7 2.4 0.033 14.9 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) K_channel_TID PF07941.11 KFM67711.1 - 0.095 13.2 7.5 0.12 12.8 7.5 1.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Rrn6 PF10214.9 KFM67711.1 - 0.13 10.8 5.2 0.15 10.6 5.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor GCD14 PF08704.10 KFM67712.1 - 1.8e-88 296.4 0.0 2.3e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 KFM67712.1 - 1.9e-05 24.4 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_31 PF13847.6 KFM67712.1 - 3.9e-05 23.5 0.0 7.1e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM67712.1 - 0.014 16.1 0.0 0.03 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFM67712.1 - 0.18 12.5 0.0 0.42 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF1347 PF07079.11 KFM67713.1 - 0.078 11.5 0.1 0.08 11.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) LRR_6 PF13516.6 KFM67715.1 - 0.0028 17.6 1.0 0.45 10.7 0.4 2.7 3 0 0 3 3 3 2 Leucine Rich repeat Ncstrn_small PF18266.1 KFM67717.1 - 3.5e-53 180.1 0.9 8.1e-53 178.9 0.9 1.6 1 0 0 1 1 1 1 Nicastrin small lobe Nicastrin PF05450.15 KFM67717.1 - 1.5e-49 168.6 0.0 2.4e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 KFM67717.1 - 0.00016 21.5 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TryThrA_C PF12319.8 KFM67717.1 - 0.018 14.5 2.7 2.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal ETF PF01012.21 KFM67719.1 - 1.6e-24 86.8 0.1 1.9e-24 86.5 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Pkinase PF00069.25 KFM67720.1 - 9.4e-66 221.9 0.0 1.1e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM67720.1 - 1.9e-39 135.5 0.0 2.3e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM67720.1 - 1.4e-06 27.9 0.0 7.9e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFM67720.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM67720.1 - 0.00066 19.7 0.4 0.0034 17.4 0.1 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFM67720.1 - 0.0038 16.2 0.0 0.0065 15.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFM67720.1 - 0.0076 15.1 0.0 0.026 13.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KFM67720.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 1 0 1 1 1 0 RIO1 family NUDIX PF00293.28 KFM67721.1 - 8.9e-07 29.0 0.5 0.077 13.0 0.7 3.5 2 1 0 2 2 2 2 NUDIX domain rve PF00665.26 KFM67722.1 - 6.4e-08 32.8 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain GSH_synth_ATP PF03917.17 KFM67723.1 - 4e-19 68.6 0.0 4.4e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synth_ATP PF03917.17 KFM67724.1 - 3.8e-88 295.8 0.0 4.3e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KFM67724.1 - 1.8e-30 105.4 0.0 2.9e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Pro_isomerase PF00160.21 KFM67725.1 - 9.4e-46 156.0 0.9 1.1e-45 155.7 0.9 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Acyl-CoA_dh_1 PF00441.24 KFM67726.1 - 2.4e-44 151.1 0.4 4.7e-44 150.2 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM67726.1 - 1.7e-26 93.1 0.1 3e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM67726.1 - 6.8e-26 90.3 0.0 1.6e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM67726.1 - 2.5e-20 73.1 0.0 3.5e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KFM67726.1 - 0.0015 19.1 0.0 0.0035 17.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal zf-C2H2_jaz PF12171.8 KFM67727.1 - 0.00075 19.7 8.9 0.082 13.2 0.5 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM67727.1 - 0.0011 19.3 3.7 1.4 9.3 0.5 3.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFM67727.1 - 0.14 12.6 14.1 0.66 10.4 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-DBF PF07535.12 KFM67727.1 - 0.57 10.3 7.2 0.68 10.1 0.4 3.3 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_4 PF13894.6 KFM67727.1 - 0.81 10.7 8.4 2.5 9.2 2.3 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM67728.1 - 2.6e-80 261.5 92.8 1.2e-07 31.8 0.4 14.3 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67728.1 - 5.6e-59 193.4 117.3 1.1e-05 25.6 3.4 13.8 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67728.1 - 7.3e-45 147.7 109.5 0.00044 20.8 0.6 13.6 14 0 0 14 14 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM67728.1 - 9.4e-27 92.6 84.6 0.00037 20.8 0.5 13.2 13 0 0 13 13 13 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM67728.1 - 5.9e-23 80.6 65.2 0.043 14.1 0.1 12.7 13 0 0 13 13 13 11 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM67728.1 - 2.1e-20 72.2 83.6 3.6e-05 23.6 1.0 13.7 13 0 0 13 13 13 11 C2H2-type zinc finger BolA PF01722.18 KFM67728.1 - 7.1e-08 32.6 16.9 0.74 10.1 0.2 7.0 2 1 4 7 7 7 3 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM67728.1 - 3.3e-07 30.2 48.6 0.39 10.8 0.6 12.6 8 3 5 13 13 13 3 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.6 KFM67728.1 - 6.9e-06 25.7 64.7 0.012 15.3 0.5 12.4 13 0 0 13 13 13 6 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM67728.1 - 0.00011 22.1 49.0 0.13 12.3 2.0 8.3 5 3 4 9 9 9 5 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM67728.1 - 0.00029 20.4 62.4 1.4 8.6 0.3 12.9 8 4 5 13 13 13 3 MYST family zinc finger domain zf-DBF PF07535.12 KFM67728.1 - 0.00043 20.3 62.4 0.75 9.9 0.1 12.5 13 0 0 13 13 13 1 DBF zinc finger zf-C2HC_2 PF13913.6 KFM67728.1 - 0.002 18.0 53.4 0.24 11.3 0.1 11.3 12 0 0 12 12 11 2 zinc-finger of a C2HC-type DUF952 PF06108.12 KFM67728.1 - 0.0038 17.2 0.7 16 5.6 0.0 5.3 3 2 5 8 8 8 0 Protein of unknown function (DUF952) GAGA PF09237.11 KFM67728.1 - 0.017 14.9 37.7 3.2 7.7 0.1 10.4 2 1 10 12 12 12 0 GAGA factor zf-C2H2_9 PF16293.5 KFM67728.1 - 0.054 13.4 48.7 3.4 7.6 0.3 12.4 3 3 10 13 13 13 0 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM67728.1 - 0.3 11.2 53.3 1.4 9.1 4.4 5.7 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type Tox-HNH-HHH PF15637.6 KFM67728.1 - 1.3 9.2 3.9 39 4.5 0.0 4.1 2 2 1 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf_UBZ PF18439.1 KFM67728.1 - 3.7 7.2 60.6 4.2 7.1 0.6 12.2 12 1 1 13 13 13 0 Ubiquitin-Binding Zinc Finger HAT_KAT11 PF08214.11 KFM67729.1 - 6e-72 242.8 0.1 6e-72 242.8 0.1 2.5 3 0 0 3 3 3 1 Histone acetylation protein KIX PF02172.16 KFM67729.1 - 4.3e-36 123.1 1.6 1.1e-35 121.8 1.6 1.7 1 0 0 1 1 1 1 KIX domain zf-TAZ PF02135.16 KFM67729.1 - 1.4e-28 99.2 52.2 2.2e-19 69.7 17.9 4.4 4 0 0 4 4 4 2 TAZ zinc finger DUF902 PF06001.13 KFM67729.1 - 1.1e-22 80.2 8.3 1.1e-22 80.2 8.3 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Creb_binding PF09030.10 KFM67729.1 - 2.9e-19 69.8 27.3 2.9e-19 69.8 27.3 12.2 6 3 5 12 12 12 1 Creb binding Bromodomain PF00439.25 KFM67729.1 - 3.9e-14 52.5 0.2 1.4e-13 50.7 0.2 2.0 1 1 0 1 1 1 1 Bromodomain ZZ PF00569.17 KFM67729.1 - 1.9e-13 49.9 13.8 1.9e-13 49.9 13.8 3.5 4 0 0 4 4 4 1 Zinc finger, ZZ type KIX_2 PF16987.5 KFM67729.1 - 1.4e-06 28.2 2.3 1.2e-05 25.2 2.3 2.9 1 0 0 1 1 1 1 KIX domain ComC PF03047.14 KFM67729.1 - 0.2 11.5 0.8 0.48 10.3 0.8 1.6 1 0 0 1 1 1 0 COMC family DUF383 PF04063.14 KFM67730.1 - 0.48 10.1 4.6 3.1 7.4 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF383) HTH_Tnp_Tc3_2 PF01498.18 KFM67731.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67731.1 - 8.4e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67732.1 - 1.6e-07 31.5 0.2 1.7e-07 31.4 0.2 1.0 1 0 0 1 1 1 1 Transposase LRR_8 PF13855.6 KFM67733.1 - 4.2e-28 96.9 40.5 7.4e-13 48.1 2.4 6.6 3 1 2 6 6 6 5 Leucine rich repeat TIR PF01582.20 KFM67733.1 - 6.3e-19 68.4 2.1 1.7e-18 67.0 2.1 1.8 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 KFM67733.1 - 1.1e-14 54.3 52.8 1.6e-05 25.2 1.5 8.6 6 2 2 9 9 9 6 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 KFM67733.1 - 4.4e-14 53.1 0.9 8.7e-14 52.1 0.9 1.5 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 KFM67733.1 - 2.7e-11 43.5 9.4 1.7e-07 31.3 3.7 2.9 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFM67733.1 - 1e-05 25.1 27.8 2.1 8.6 1.1 9.7 9 0 0 9 9 9 2 Leucine Rich repeat LRRNT PF01462.18 KFM67733.1 - 3.9e-05 23.2 2.2 3.9e-05 23.2 2.2 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFM67733.1 - 0.00021 20.9 18.3 0.023 14.2 0.3 4.5 2 1 2 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 KFM67734.1 - 5.4e-09 35.7 4.7 8.1e-09 35.1 3.2 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KFM67734.1 - 6.7e-06 26.3 5.6 1.2e-05 25.5 3.8 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM67734.1 - 0.039 13.5 0.2 0.058 12.9 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat FAST_2 PF08368.12 KFM67734.1 - 0.078 13.8 0.2 3.3 8.5 0.0 2.5 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 2 LRR_6 PF13516.6 KFM67734.1 - 0.36 11.0 5.1 3 8.2 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KFM67734.1 - 0.75 10.6 6.9 20 6.2 0.5 4.0 4 1 0 4 4 4 0 Leucine Rich Repeat SCAN PF02023.17 KFM67735.1 - 0.00041 20.1 0.0 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 SCAN domain zf-CCHC_4 PF14392.6 KFM67735.1 - 0.019 14.7 0.4 0.019 14.7 0.4 2.4 2 1 0 2 2 2 0 Zinc knuckle zf-CHC2 PF01807.20 KFM67735.1 - 0.048 13.5 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 CHC2 zinc finger HIP1_clath_bdg PF16515.5 KFM67735.1 - 1.2 9.8 11.3 1.8 9.2 5.3 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-CCHC PF00098.23 KFM67735.1 - 2.7 8.2 5.2 0.43 10.7 1.5 1.6 2 0 0 2 2 2 0 Zinc knuckle ASC PF00858.24 KFM67736.1 - 8.7e-09 34.8 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel SAP PF02037.27 KFM67737.1 - 0.00051 19.7 0.1 0.0011 18.7 0.1 1.6 1 0 0 1 1 1 1 SAP domain Mis14 PF08641.12 KFM67738.1 - 0.0001 22.7 0.5 0.00022 21.5 0.5 1.7 1 1 0 1 1 1 1 Kinetochore protein Mis14 like Turandot PF07240.11 KFM67738.1 - 0.096 12.7 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 Stress-inducible humoral factor Turandot NAD_binding_6 PF08030.12 KFM67739.1 - 4.6e-27 95.1 0.0 1.4e-26 93.5 0.0 1.8 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFM67739.1 - 3.3e-23 82.2 10.5 6.3e-23 81.2 10.5 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.32 KFM67739.1 - 1.3e-21 74.4 3.8 1.9e-06 27.0 0.2 3.7 3 0 0 3 3 3 3 EF hand FAD_binding_8 PF08022.12 KFM67739.1 - 2.4e-21 75.9 0.0 4.3e-18 65.4 0.0 2.8 2 0 0 2 2 2 2 FAD-binding domain EF-hand_7 PF13499.6 KFM67739.1 - 4.8e-21 75.0 12.6 2.5e-10 40.7 0.4 2.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFM67739.1 - 1.3e-19 68.3 4.4 9.1e-06 25.2 0.0 4.6 5 0 0 5 5 4 3 EF-hand domain EF-hand_5 PF13202.6 KFM67739.1 - 2.4e-16 58.4 5.1 8.7e-05 21.9 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFM67739.1 - 7.7e-14 51.3 6.8 0.0004 20.2 0.2 4.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KFM67739.1 - 1.4e-05 25.3 0.1 0.058 13.7 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain NAD_binding_1 PF00175.21 KFM67739.1 - 0.00041 21.0 0.0 0.021 15.5 0.0 2.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain SPARC_Ca_bdg PF10591.9 KFM67739.1 - 0.038 14.3 1.9 0.74 10.2 0.1 3.4 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFM67739.1 - 0.039 13.9 1.9 8.9 6.3 0.1 3.3 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KFM67739.1 - 0.1 13.5 0.3 1.1 10.2 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 KFM67739.1 - 0.33 11.3 2.6 64 4.0 0.0 4.2 3 1 1 4 4 4 0 EF-hand domain HTH_Tnp_Tc3_2 PF01498.18 KFM67740.1 - 2.2e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67740.1 - 9e-14 51.4 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67742.1 - 3.2e-17 62.5 2.2 6.7e-17 61.5 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67742.1 - 7.2e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5131 PF07505.11 KFM67744.1 - 0.024 14.1 0.5 0.03 13.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) zf-CCHC_4 PF14392.6 KFM67744.1 - 0.38 10.5 12.8 0.33 10.7 1.6 2.5 1 1 1 2 2 2 0 Zinc knuckle Inositol_P PF00459.25 KFM67745.1 - 5.2e-26 91.8 0.1 6.1e-26 91.5 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Inositol_P PF00459.25 KFM67746.1 - 4.7e-46 157.5 0.1 5.1e-46 157.4 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PDCD7 PF16021.5 KFM67747.1 - 4.9e-47 160.5 32.7 4.9e-47 160.5 32.7 2.0 1 1 1 2 2 2 2 Programmed cell death protein 7 DUF2203 PF09969.9 KFM67747.1 - 9.1 7.0 17.1 14 6.4 7.1 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1151 PF06625.11 KFM67748.1 - 0.009 15.9 4.4 0.0099 15.8 3.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1151) HET-s_218-289 PF11558.8 KFM67749.1 - 0.042 13.9 3.8 2.9 8.0 0.1 5.0 5 0 0 5 5 5 0 Het-s 218-289 Cyclin PF08613.11 KFM67749.1 - 0.048 14.0 11.5 31 4.9 0.0 6.5 5 2 2 7 7 7 0 Cyclin DUF3458 PF11940.8 KFM67749.1 - 0.15 12.5 10.0 1.3 9.5 0.1 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF3458) Ig-like fold Ole-e-6 PF09253.10 KFM67750.1 - 0.0028 17.6 4.3 0.24 11.4 0.6 3.7 2 0 0 2 2 2 2 Pollen allergen ole e 6 PPTA PF01239.22 KFM67752.1 - 2.3e-11 43.0 6.0 7.9e-07 28.6 1.7 3.6 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat TMEM71 PF15121.6 KFM67752.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 TMEM71 protein family Spo7_2_N PF15407.6 KFM67753.1 - 0.019 14.6 0.1 0.047 13.3 0.1 1.7 1 0 0 1 1 1 0 Sporulation protein family 7 Voltage_CLC PF00654.20 KFM67754.1 - 5.8e-11 42.2 0.1 5.8e-11 42.2 0.1 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel Voltage_CLC PF00654.20 KFM67755.1 - 7.6e-17 61.6 4.3 9.4e-17 61.3 4.3 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KFM67755.1 - 2.6e-06 27.8 0.7 0.00027 21.3 0.1 2.6 2 1 0 2 2 2 2 CBS domain LacI PF00356.21 KFM67755.1 - 0.03 14.1 1.5 0.07 12.9 1.5 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family FANCF PF11107.8 KFM67756.1 - 8e-12 45.0 3.0 9.5e-12 44.8 3.0 1.0 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) DUF5310 PF17237.2 KFM67756.1 - 0.0065 16.3 1.6 0.016 15.1 0.1 2.4 3 0 0 3 3 3 1 Family of unknown function (DUF5310) SAS-6_N PF16531.5 KFM67756.1 - 0.086 13.4 2.4 0.1 13.2 0.4 2.0 1 1 1 2 2 2 0 Centriolar protein SAS N-terminal TERF2_RBM PF16772.5 KFM67756.1 - 0.2 11.1 0.1 2.6 7.5 0.1 2.2 2 0 0 2 2 2 0 Telomeric repeat-binding factor 2 Rap1-binding motif zinc_ribbon_2 PF13240.6 KFM67757.1 - 0.0014 18.3 0.4 0.0027 17.3 0.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KFM67757.1 - 0.062 13.3 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KFM67757.1 - 0.082 12.3 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KFM67757.1 - 0.089 12.3 0.1 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding FXa_inhibition PF14670.6 KFM67760.1 - 2.2e-21 75.8 65.4 1.3e-11 44.6 8.8 8.3 7 1 0 7 7 7 3 Coagulation Factor Xa inhibitory site Sushi PF00084.20 KFM67760.1 - 2.5e-20 72.8 24.1 2.7e-11 43.9 0.5 6.9 6 1 1 7 7 7 3 Sushi repeat (SCR repeat) HYR PF02494.16 KFM67760.1 - 1.1e-17 64.1 8.2 4.5e-16 59.0 0.1 3.0 3 0 0 3 3 3 2 HYR domain cEGF PF12662.7 KFM67760.1 - 1.3e-16 60.1 52.2 6.6e-06 26.0 0.9 8.2 8 1 0 8 8 8 5 Complement Clr-like EGF-like EGF_CA PF07645.15 KFM67760.1 - 2.3e-12 46.9 62.4 2.9e-07 30.6 10.4 7.6 7 0 0 7 7 7 3 Calcium-binding EGF domain EGF_3 PF12947.7 KFM67760.1 - 0.0028 17.8 4.5 0.0028 17.8 4.5 6.1 7 0 0 7 7 7 2 EGF domain EGF PF00008.27 KFM67760.1 - 0.34 11.2 43.4 0.3 11.4 9.1 6.4 7 0 0 7 7 7 0 EGF-like domain RANK_CRD_2 PF18278.1 KFM67760.1 - 5.3 7.3 14.1 13 6.1 0.1 5.1 4 0 0 4 4 4 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 PHD_4 PF16866.5 KFM67761.1 - 3.8e-22 78.1 17.6 3.8e-22 78.1 17.6 2.9 2 0 0 2 2 2 1 PHD-finger zf-CXXC PF02008.20 KFM67761.1 - 8.6e-14 51.3 21.1 8.6e-14 51.3 21.1 2.4 2 0 0 2 2 2 1 CXXC zinc finger domain JmjC PF02373.22 KFM67761.1 - 3.9e-08 33.7 1.6 0.0011 19.4 0.1 2.9 3 0 0 3 3 3 2 JmjC domain, hydroxylase LRR_6 PF13516.6 KFM67761.1 - 1.1e-07 31.3 9.4 0.38 10.9 0.0 6.7 7 0 0 7 7 7 2 Leucine Rich repeat Cupin_8 PF13621.6 KFM67761.1 - 1.3e-07 31.6 1.4 1.4e-06 28.3 0.2 2.7 2 1 0 2 2 2 1 Cupin-like domain F-box-like PF12937.7 KFM67761.1 - 4.9e-07 29.5 0.5 1.3e-06 28.2 0.5 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFM67761.1 - 9.3e-06 25.9 2.4 0.31 11.5 0.1 4.4 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) JHD PF17811.1 KFM67761.1 - 1.1e-05 25.9 0.0 3.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Jumonji helical domain F-box PF00646.33 KFM67761.1 - 1.5e-05 24.7 0.2 6.8e-05 22.6 0.2 2.2 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 KFM67761.1 - 0.00081 19.1 6.8 0.14 12.0 0.2 4.2 3 1 0 3 3 3 2 Leucine rich repeat Cupin_1 PF00190.22 KFM67761.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_4 PF08007.12 KFM67761.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Amnionless PF14828.6 KFM67761.1 - 2.5 6.9 15.6 4 6.2 15.6 1.2 1 0 0 1 1 1 0 Amnionless HTH_Tnp_Tc3_2 PF01498.18 KFM67763.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67763.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67763.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67763.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67763.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM67764.1 - 1.4e-16 60.6 0.0 1.9e-15 56.9 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67764.1 - 1.6e-16 60.3 1.0 2.5e-16 59.7 1.0 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67765.1 - 8.6e-14 51.5 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67765.1 - 9.8e-14 51.4 1.5 1.9e-13 50.5 1.5 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM67766.1 - 2.2e-16 59.9 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67766.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HMG_box_5 PF14887.6 KFM67766.1 - 0.037 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Otopetrin PF03189.13 KFM67767.1 - 1.1e-45 156.3 20.9 2.8e-45 155.0 20.9 1.6 1 1 0 1 1 1 1 Otopetrin TCR_zetazeta PF11628.8 KFM67767.1 - 2.2 8.0 12.2 2.2 8.0 0.4 3.2 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain Otopetrin PF03189.13 KFM67768.1 - 8.1e-09 34.8 2.3 9.1e-09 34.6 2.3 1.0 1 0 0 1 1 1 1 Otopetrin DUF5362 PF17319.2 KFM67768.1 - 0.018 14.9 0.3 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5362) DUF2207 PF09972.9 KFM67770.1 - 0.14 10.9 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SNF PF00209.18 KFM67772.1 - 1.7e-22 79.8 0.9 1.8e-22 79.7 0.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DDE_3 PF13358.6 KFM67773.1 - 5.5e-16 58.6 0.1 2.3e-15 56.6 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67773.1 - 1.6e-10 41.1 1.0 2.8e-10 40.3 1.0 1.4 1 0 0 1 1 1 1 Transposase SNF PF00209.18 KFM67774.1 - 2e-106 356.8 12.2 2.7e-106 356.3 12.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DDE_3 PF13358.6 KFM67774.1 - 5.1e-08 32.8 0.0 8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SNF PF00209.18 KFM67775.1 - 2.3e-09 36.5 0.7 2.6e-09 36.3 0.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ribosomal_L10 PF00466.20 KFM67776.1 - 3.9e-09 36.5 0.1 7.4e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 LUC7 PF03194.15 KFM67776.1 - 0.068 12.8 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 LUC7 N_terminus HTH_Tnp_Tc3_2 PF01498.18 KFM67779.1 - 4.5e-16 58.8 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67779.1 - 2.2e-13 50.2 0.0 3.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67779.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67779.1 - 0.0026 17.5 0.6 0.0077 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67779.1 - 0.03 14.4 0.4 0.092 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM67779.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RhoGEF PF00621.20 KFM67782.1 - 6.9e-14 52.5 0.3 6.9e-14 52.5 0.3 3.3 3 1 0 3 3 3 1 RhoGEF domain TFR_dimer PF04253.15 KFM67782.1 - 0.57 10.3 4.1 10 6.3 0.0 4.3 5 0 0 5 5 5 0 Transferrin receptor-like dimerisation domain TCTP PF00838.17 KFM67782.1 - 1 9.7 5.1 1.4 9.2 3.7 2.0 1 1 0 1 1 1 0 Translationally controlled tumour protein HTH_48 PF17906.1 KFM67784.1 - 2e-07 31.0 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM67784.1 - 0.00055 20.5 2.2 0.0045 17.6 0.4 2.0 1 1 1 2 2 2 2 Homeodomain-like domain Inhibitor_I24 PF10465.9 KFM67786.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 PinA peptidase inhibitor SLX9 PF15341.6 KFM67787.1 - 0.21 12.0 0.9 5.6 7.4 0.1 2.5 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 BCLP PF12304.8 KFM67789.1 - 0.0085 15.7 0.9 0.0085 15.7 0.9 2.1 1 1 1 2 2 2 1 Beta-casein like protein 7TMR-DISM_7TM PF07695.11 KFM67789.1 - 0.087 12.7 5.8 0.14 12.1 5.8 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling CPP1-like PF11833.8 KFM67789.1 - 2.8 7.5 5.0 5.7 6.6 5.0 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DDE_1 PF03184.19 KFM67790.1 - 1.7e-17 63.6 0.1 3e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM67790.1 - 5.2e-12 45.6 0.4 1.1e-11 44.5 0.4 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM67790.1 - 0.0033 17.2 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3372 PF11852.8 KFM67790.1 - 0.091 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) HTH_Tnp_Tc3_2 PF01498.18 KFM67791.1 - 7.1e-15 55.0 1.6 1.3e-14 54.2 1.6 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67791.1 - 6.9e-12 45.3 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Kelch_2 PF07646.15 KFM67791.1 - 0.021 14.8 0.4 0.087 12.8 0.3 2.1 2 0 0 2 2 2 0 Kelch motif FMN_dh PF01070.18 KFM67792.1 - 7.5e-18 64.7 0.0 8.3e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase SPOR PF05036.13 KFM67792.1 - 0.081 13.3 0.0 0.16 12.4 0.0 1.4 2 0 0 2 2 2 0 Sporulation related domain Foamy_virus_ENV PF03408.14 KFM67792.1 - 0.13 10.1 0.0 0.14 10.0 0.0 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein ThiC_Rad_SAM PF01964.18 KFM67792.1 - 0.22 10.3 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Radical SAM ThiC family FMN_dh PF01070.18 KFM67793.1 - 1e-41 143.1 0.7 1.1e-41 143.0 0.7 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KFM67793.1 - 5.3e-06 25.8 0.0 5.7e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFM67793.1 - 1.2e-05 24.5 0.1 1.3e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KFM67793.1 - 0.0099 15.4 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KFM67793.1 - 0.044 13.2 0.3 0.052 12.9 0.3 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 KFM67793.1 - 0.051 12.8 0.0 0.051 12.8 0.0 1.0 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Exo_endo_phos_2 PF14529.6 KFM67794.1 - 2.1e-06 27.6 0.0 4.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM67794.1 - 0.039 13.5 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family G6PD_C PF02781.16 KFM67795.1 - 2.8e-119 397.6 0.0 4e-119 397.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFM67795.1 - 1.8e-61 207.9 0.1 4.1e-61 206.7 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KFM67795.1 - 0.017 15.9 0.1 8.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Porphobil_deam PF01379.20 KFM67796.1 - 3e-78 262.0 0.0 3.8e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KFM67796.1 - 3.5e-20 72.2 0.7 1.1e-19 70.5 0.1 2.0 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain MutS_I PF01624.20 KFM67798.1 - 2.2e-29 102.0 0.1 2.4e-29 101.9 0.1 1.0 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 KFM67800.1 - 1.4e-33 116.7 0.0 1.9e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KFM67800.1 - 3.5e-13 49.7 1.1 6.7e-13 48.8 0.3 1.9 2 0 0 2 2 2 1 MutS family domain IV MutS_V PF00488.21 KFM67800.1 - 7.9e-05 22.8 0.6 0.00015 21.8 0.6 1.5 1 0 0 1 1 1 1 MutS domain V AAA_23 PF13476.6 KFM67800.1 - 0.023 15.2 5.0 2 8.8 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 KFM67800.1 - 0.2 11.4 0.1 0.44 10.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_V PF00488.21 KFM67801.1 - 1.1e-38 133.1 0.0 1.3e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 MutS domain V RecQ_Zn_bind PF16124.5 KFM67801.1 - 0.052 14.3 1.4 15 6.4 0.1 2.7 2 1 0 2 2 2 0 RecQ zinc-binding FLYWCH PF04500.16 KFM67802.1 - 8.7e-10 38.6 3.2 1.1e-09 38.3 3.2 1.1 1 0 0 1 1 1 1 FLYWCH zinc finger domain RE_HaeIII PF09556.10 KFM67803.1 - 0.14 11.2 0.1 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 HaeIII restriction endonuclease LigT_PEase PF02834.16 KFM67804.1 - 0.13 12.5 0.0 0.43 10.8 0.0 1.9 2 0 0 2 2 2 0 LigT like Phosphoesterase HEAT_2 PF13646.6 KFM67807.1 - 0.00053 20.3 0.1 0.56 10.6 0.0 2.3 2 0 0 2 2 2 2 HEAT repeats DCB PF16213.5 KFM67807.1 - 0.057 13.1 1.4 0.088 12.5 1.4 1.4 1 1 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 HEAT PF02985.22 KFM67810.1 - 0.058 13.7 3.5 0.14 12.5 0.7 2.4 2 1 1 3 3 3 0 HEAT repeat Arm PF00514.23 KFM67810.1 - 0.19 11.8 2.7 0.22 11.6 0.3 2.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat ALS2CR8 PF15299.6 KFM67813.1 - 0.00049 20.1 0.3 0.00053 19.9 0.3 1.0 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Glyco_transf_22 PF03901.17 KFM67814.1 - 2.6e-07 30.3 0.1 2.6e-07 30.3 0.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_transf_22 PF03901.17 KFM67815.1 - 6.7e-08 32.2 3.7 7.5e-08 32.0 3.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3989 PF13150.6 KFM67815.1 - 0.06 13.1 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) YlqD PF11068.8 KFM67816.1 - 0.016 15.5 4.6 0.016 15.5 4.6 3.0 1 1 2 3 3 3 0 YlqD protein SKA1 PF07160.12 KFM67816.1 - 0.25 11.2 21.7 0.044 13.6 15.3 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 V_ATPase_I PF01496.19 KFM67816.1 - 0.36 8.7 16.9 0.46 8.3 16.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 KFM67816.1 - 0.46 10.8 2.7 2.8 8.2 0.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MS_channel PF00924.18 KFM67816.1 - 1.7 8.1 4.7 0.55 9.8 1.8 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel Spc7 PF08317.11 KFM67816.1 - 1.8 7.4 33.6 0.22 10.3 4.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Jacalin PF01419.17 KFM67816.1 - 1.9 8.4 6.5 0.54 10.2 0.5 2.4 2 1 1 3 3 3 0 Jacalin-like lectin domain TMF_TATA_bd PF12325.8 KFM67816.1 - 3.5 7.9 27.5 1.3 9.3 4.4 3.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 KFM67816.1 - 4.9 7.2 29.9 0.017 15.2 9.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 KFM67816.1 - 7.7 7.2 16.9 8.7 7.1 0.7 3.4 2 1 1 3 3 3 0 SlyX Sec16 PF12932.7 KFM67816.1 - 8 7.1 12.0 38 4.9 11.6 2.4 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region IFT81_CH PF18383.1 KFM67817.1 - 3e-52 176.1 3.2 3e-52 176.1 3.2 2.9 2 1 1 3 3 3 1 Intraflagellar transport 81 calponin homology domain Golgin_A5 PF09787.9 KFM67817.1 - 0.014 14.9 34.4 0.072 12.5 10.7 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 Laminin_II PF06009.12 KFM67817.1 - 0.025 14.6 2.1 0.025 14.6 2.1 3.9 1 1 3 4 4 4 0 Laminin Domain II DHR10 PF18595.1 KFM67817.1 - 0.6 10.2 36.8 0.72 9.9 2.6 4.2 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain Hemerythrin PF01814.23 KFM67817.1 - 2.3 8.9 9.4 0.93 10.1 4.9 2.6 2 2 0 2 2 2 0 Hemerythrin HHE cation binding domain TMPIT PF07851.13 KFM67817.1 - 2.8 7.1 29.9 0.64 9.2 5.3 3.4 3 1 1 4 4 4 0 TMPIT-like protein GAS PF13851.6 KFM67817.1 - 3.5 6.9 45.5 9.3 5.5 8.2 4.7 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding T2SSM PF04612.12 KFM67817.1 - 7 6.7 9.4 6.5 6.8 0.3 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M SPC25 PF06703.11 KFM67818.1 - 2.6e-46 157.4 0.0 3e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Leader_CPA1 PF08252.11 KFM67818.1 - 0.03 13.7 0.3 0.065 12.6 0.3 1.6 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide Sugar_tr PF00083.24 KFM67819.1 - 6.4e-11 41.8 7.9 2.5e-09 36.5 7.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM67819.1 - 1.1e-08 34.4 6.8 1.1e-08 34.4 6.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TrbC PF04956.13 KFM67819.1 - 0.034 14.4 0.3 0.034 14.4 0.3 1.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Peptidase_M48_N PF16491.5 KFM67819.1 - 0.04 13.8 0.6 0.04 13.8 0.6 2.1 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices DUF1430 PF07242.11 KFM67819.1 - 0.29 11.4 4.4 0.25 11.6 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1430) DUF4131 PF13567.6 KFM67819.1 - 5.4 6.6 7.7 12 5.5 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) LPMO_10 PF03067.15 KFM67820.1 - 2e-32 113.5 0.3 2.3e-32 113.2 0.3 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading HTH_Tnp_Tc3_2 PF01498.18 KFM67821.1 - 4.9e-16 58.7 3.5 6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67821.1 - 7.1e-13 48.5 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67821.1 - 2e-07 30.6 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67821.1 - 0.0025 17.6 0.6 0.0079 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67821.1 - 0.03 14.5 0.4 0.094 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM67821.1 - 2 9.1 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain EF-hand_1 PF00036.32 KFM67822.1 - 1.4e-08 33.7 0.4 0.094 12.3 0.0 4.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFM67822.1 - 2.1e-08 33.5 0.5 0.012 15.5 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFM67822.1 - 5.3e-07 30.0 0.1 0.014 15.9 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFM67822.1 - 0.00011 22.0 1.9 0.17 11.7 0.1 3.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KFM67822.1 - 0.0081 16.5 0.1 5.8 7.3 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain zf-H2C2_2 PF13465.6 KFM67823.1 - 4.6e-77 251.3 56.9 2.2e-09 37.3 0.8 10.5 11 0 0 11 11 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67823.1 - 5.6e-50 165.1 92.4 1.3e-06 28.5 1.7 11.1 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67823.1 - 3.6e-34 114.5 82.1 0.00042 20.9 0.6 11.1 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM67823.1 - 7.7e-28 95.9 66.3 1.1e-05 25.2 0.7 10.6 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFM67823.1 - 1.6e-22 79.2 70.1 3.3e-05 24.1 0.7 10.3 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM67823.1 - 2.4e-12 46.8 50.1 0.03 14.6 0.1 10.0 9 1 1 10 10 10 6 Zinc-finger double-stranded RNA-binding DUF4825 PF16107.5 KFM67823.1 - 5.1e-07 29.8 0.0 1.4 9.1 0.0 5.5 1 1 5 6 6 6 1 Domain of unknown function (DUF4825) ADK_lid PF05191.14 KFM67823.1 - 3e-06 27.1 39.7 0.015 15.3 0.5 7.3 6 2 0 6 6 6 3 Adenylate kinase, active site lid zf_UBZ PF18439.1 KFM67823.1 - 0.00016 21.2 37.2 2 8.1 0.1 9.7 10 0 0 10 10 10 3 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KFM67823.1 - 0.00026 21.7 31.8 0.56 11.0 2.0 5.4 1 1 5 7 7 7 4 zinc-ribbon family zf-H2C2_5 PF13909.6 KFM67823.1 - 0.00093 18.9 70.6 0.032 14.0 0.7 11.4 11 0 0 11 11 11 4 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 KFM67823.1 - 0.001 19.1 35.1 1.1 9.5 0.4 7.6 1 1 9 10 10 10 3 Zinc ribbon domain DUF2256 PF10013.9 KFM67823.1 - 0.0029 17.7 31.6 0.94 9.7 0.0 9.2 10 0 0 10 10 10 2 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.18 KFM67823.1 - 0.0036 17.6 13.9 3.2 8.1 0.4 5.5 2 1 2 4 4 4 1 BolA-like protein Baculo_IE-1 PF05290.11 KFM67823.1 - 0.0058 16.6 26.1 3.4 7.6 0.0 6.2 1 1 3 4 4 4 2 Baculovirus immediate-early protein (IE-0) zf_ZIC PF18366.1 KFM67823.1 - 0.006 16.7 44.6 0.23 11.6 0.2 9.0 2 2 7 9 9 9 1 Zic proteins zinc finger domain GAGA PF09237.11 KFM67823.1 - 0.0069 16.2 21.6 4.8 7.1 0.1 6.9 2 1 6 8 8 8 2 GAGA factor HypA PF01155.19 KFM67823.1 - 0.0081 16.2 25.1 0.45 10.5 1.8 5.5 1 1 4 5 5 5 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zf_RING PF16744.5 KFM67823.1 - 0.013 15.6 39.5 11 6.2 0.8 9.0 1 1 6 8 8 8 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 KFM67823.1 - 0.038 13.9 34.8 6.8 6.7 0.1 9.3 8 2 0 8 8 8 0 Prokaryotic RING finger family 1 DUF4499 PF14934.6 KFM67823.1 - 0.065 13.6 1.4 20 5.6 0.1 3.6 3 1 1 5 5 3 0 Domain of unknown function (DUF4499) zf-C2H2_2 PF12756.7 KFM67823.1 - 0.066 13.6 62.0 0.57 10.5 10.1 8.5 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM67823.1 - 0.1 12.2 44.5 3.5 7.3 0.3 9.3 2 2 8 10 10 10 0 MYST family zinc finger domain Parvo_coat_N PF08398.10 KFM67823.1 - 0.16 12.2 0.0 7.1 6.9 0.0 3.1 3 1 1 4 4 3 0 Parvovirus coat protein VP1 zf-C2HC_2 PF13913.6 KFM67823.1 - 0.2 11.6 0.0 0.2 11.6 0.0 8.2 9 0 0 9 9 8 0 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM67823.1 - 0.4 10.8 31.9 0.42 10.7 2.5 4.5 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type HNH_5 PF14279.6 KFM67823.1 - 3.4 7.6 42.7 4.9 7.1 0.1 9.0 5 3 2 7 7 7 0 HNH endonuclease RVT_1 PF00078.27 KFM67824.1 - 3.4e-46 157.5 0.4 4.8e-46 157.1 0.4 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4882 PF16223.5 KFM67824.1 - 0.019 14.2 0.6 0.033 13.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) Glyco_hydro_67M PF07488.12 KFM67824.1 - 0.059 12.4 0.3 0.1 11.7 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain DUF2185 PF09951.9 KFM67824.1 - 0.14 12.0 0.2 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) HTH_Tnp_Tc3_2 PF01498.18 KFM67825.1 - 4.3e-16 58.9 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67825.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67825.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67825.1 - 0.0026 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67825.1 - 0.026 14.7 0.4 0.086 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM67825.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67826.1 - 2.3e-16 59.8 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67826.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67829.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67829.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67829.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67829.1 - 0.0025 17.6 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67829.1 - 2.1 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Aminotran_1_2 PF00155.21 KFM67830.1 - 7e-11 41.9 0.0 8.2e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KFM67830.1 - 0.083 11.7 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Allinase Aminotran_5 PF00266.19 KFM67830.1 - 0.16 10.9 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V HTH_Tnp_Tc3_2 PF01498.18 KFM67831.1 - 2.8e-17 62.7 1.5 4.6e-17 62.0 1.5 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM67831.1 - 9e-06 26.2 6.7 2.2e-05 25.0 2.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67831.1 - 0.00064 19.4 1.3 0.096 12.5 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67831.1 - 0.0012 18.9 3.7 0.028 14.5 0.4 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM67831.1 - 0.0036 17.2 1.0 0.024 14.6 0.1 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM67831.1 - 0.0049 16.4 0.6 1.3 8.7 0.0 3.0 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 KFM67831.1 - 0.016 15.2 0.6 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix FUR PF01475.19 KFM67831.1 - 0.055 13.6 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_7 PF02796.15 KFM67831.1 - 0.088 12.9 0.7 0.16 12.0 0.2 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_26 PF13443.6 KFM67831.1 - 0.16 12.4 2.4 9.2 6.8 0.6 2.9 2 1 1 3 3 3 0 Cro/C1-type HTH DNA-binding domain SPICE PF15678.5 KFM67832.1 - 0.017 14.5 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression VPR PF00522.18 KFM67833.1 - 0.2 11.7 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 VPR/VPX protein PNP_UDP_1 PF01048.20 KFM67835.1 - 1.7e-47 161.7 0.1 1.9e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily tRNA_bind PF01588.20 KFM67836.1 - 1.1e-32 112.0 0.1 2.4e-32 110.9 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GAGA_bind PF06217.12 KFM67836.1 - 0.98 9.6 6.3 1.2 9.3 6.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family PhoLip_ATPase_N PF16209.5 KFM67837.1 - 7.4e-19 67.2 5.0 1.4e-18 66.3 5.0 1.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KFM67837.1 - 7.6e-07 28.8 0.0 1.6e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFM67838.1 - 4.6e-15 56.5 0.1 3.9e-05 24.1 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase PhoLip_ATPase_C PF16212.5 KFM67838.1 - 1.7e-14 54.2 3.4 2.6e-14 53.6 3.4 1.3 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 KFM67838.1 - 5e-11 42.5 0.1 3e-09 36.8 0.0 3.0 2 1 1 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFM67838.1 - 0.00034 20.5 0.1 0.0051 16.6 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase POTRA_TamA_1 PF17243.2 KFM67838.1 - 0.12 12.4 0.1 3 8.0 0.0 2.4 2 0 0 2 2 2 0 POTRA domain TamA domain 1 HTH_Tnp_Tc3_2 PF01498.18 KFM67839.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67839.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67840.1 - 2.3e-19 69.4 3.9 5.2e-19 68.3 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67840.1 - 3.9e-16 59.1 0.0 2e-15 56.8 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM67840.1 - 3.3e-07 30.8 2.0 3.3e-07 30.8 2.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM67840.1 - 2.1e-05 24.2 4.8 0.00011 21.8 0.1 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67840.1 - 2.2e-05 24.5 3.1 0.0013 18.8 0.3 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM67840.1 - 3.9e-05 23.7 1.5 0.012 15.7 0.1 2.7 3 0 0 3 3 2 2 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM67840.1 - 4.2e-05 23.5 1.0 0.0005 20.0 0.2 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM67840.1 - 6.4e-05 22.8 1.0 0.00083 19.2 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM67840.1 - 0.00083 19.3 0.6 0.011 15.7 0.0 2.4 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_22 PF13309.6 KFM67840.1 - 0.019 15.0 0.0 4 7.6 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_17 PF12728.7 KFM67840.1 - 0.081 13.1 0.1 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM67840.1 - 1.3 8.5 4.3 5.4 6.5 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 KFM67840.1 - 1.4 8.8 4.8 3.9 7.3 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain NOT2_3_5 PF04153.18 KFM67841.1 - 5.2e-32 110.7 0.2 1.1e-31 109.6 0.2 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Myb_DNA-bind_5 PF13873.6 KFM67842.1 - 3.1e-07 30.4 0.0 3.7e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Helicase_C PF00271.31 KFM67843.1 - 1.6e-08 34.8 0.1 3.1e-07 30.7 0.1 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DDE_Tnp_1_7 PF13843.6 KFM67844.1 - 1.1e-82 278.2 0.1 5.4e-82 275.9 0.0 1.8 2 0 0 2 2 2 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM67844.1 - 0.0016 19.2 8.0 0.0016 19.2 8.0 2.0 2 0 0 2 2 2 1 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.16 KFM67844.1 - 0.11 12.8 5.8 0.27 11.6 5.8 1.6 1 0 0 1 1 1 0 C1 domain C1_4 PF07975.12 KFM67844.1 - 1.4 9.2 6.0 4.5 7.6 6.0 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain SNF2_N PF00176.23 KFM67846.1 - 1.9e-38 132.1 2.6 2.2e-38 131.9 2.6 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KFM67847.1 - 3.3e-47 160.2 18.0 3.3e-47 160.2 18.0 2.5 2 0 0 2 2 2 1 DNA-binding domain SNF2_N PF00176.23 KFM67847.1 - 7.2e-11 41.4 0.7 3.2e-10 39.2 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain NCD1 PF04904.13 KFM67847.1 - 0.12 12.4 0.1 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Siva PF05458.12 KFM67847.1 - 1.3 8.6 4.3 1.8 8.3 3.3 1.7 2 0 0 2 2 2 0 Cd27 binding protein (Siva) AAA_21 PF13304.6 KFM67847.1 - 4.8 6.9 7.8 1.7 8.4 4.7 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RRM_1 PF00076.22 KFM67848.1 - 4.5e-18 64.8 0.0 4.9e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KFM67848.1 - 0.022 14.4 0.2 0.034 13.8 0.2 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain SET_assoc PF11767.8 KFM67848.1 - 0.075 12.7 0.1 0.097 12.3 0.1 1.1 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Asp_protease_2 PF13650.6 KFM67850.1 - 1.5e-09 38.3 0.0 1.7e-09 38.2 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM67850.1 - 2.3e-09 37.7 0.0 2.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KFM67850.1 - 0.079 12.8 0.1 0.087 12.6 0.1 1.2 1 1 0 1 1 1 0 Aspartyl protease RRM_1 PF00076.22 KFM67851.1 - 1.3e-06 28.1 0.1 1.9e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0051 PF01458.17 KFM67851.1 - 0.038 13.7 3.5 0.033 13.9 2.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein family (UPF0051) RRM_5 PF13893.6 KFM67851.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGEF PF00617.19 KFM67853.1 - 2.3e-13 50.7 1.6 2.4e-13 50.7 1.6 1.0 1 0 0 1 1 1 1 RasGEF domain HTH_Tnp_Tc3_2 PF01498.18 KFM67854.1 - 4.2e-16 59.0 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67854.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67854.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67854.1 - 0.0023 17.7 0.6 0.007 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67854.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67855.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67855.1 - 9.4e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_T PF00929.24 KFM67856.1 - 2.8e-08 34.5 0.0 6.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 KFM67856.1 - 5.4e-08 33.3 1.6 9.9e-08 32.4 1.6 1.4 1 0 0 1 1 1 1 ElonginA binding-protein 1 DUF5051 PF16473.5 KFM67856.1 - 0.0008 19.4 0.0 0.0035 17.3 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 KFM67856.1 - 0.013 15.3 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 3'-5' exonuclease TINF2_N PF14973.6 KFM67856.1 - 0.08 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus CCDC117 PF15810.5 KFM67856.1 - 0.14 12.4 2.2 0.78 10.0 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 117 zf-H2C2_2 PF13465.6 KFM67857.1 - 1.8e-15 56.5 26.1 1e-06 28.9 3.9 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67857.1 - 7.5e-07 29.3 39.0 0.0011 19.3 1.0 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type Homeodomain PF00046.29 KFM67857.1 - 1.3e-05 25.0 0.1 3.9e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain zf-C2H2_4 PF13894.6 KFM67857.1 - 0.00044 20.9 36.1 0.035 14.9 0.9 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM67857.1 - 0.0019 18.1 27.6 0.0023 17.9 1.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFM67857.1 - 1.1 10.1 10.3 0.87 10.4 3.3 3.0 2 1 1 3 3 3 0 zinc-ribbon family zf-C2H2_11 PF16622.5 KFM67857.1 - 1.6 8.6 13.1 2.6 7.9 0.1 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM67857.1 - 7.2 7.0 27.6 0.09 13.1 1.7 4.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFM67857.1 - 7.3 6.3 12.9 1.3 8.7 0.1 3.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Prefoldin PF02996.17 KFM67858.1 - 3e-33 114.3 0.4 3e-33 114.3 0.4 1.4 2 0 0 2 2 2 1 Prefoldin subunit NBP1 PF08537.10 KFM67858.1 - 0.0095 15.4 5.5 0.012 15.1 5.5 1.1 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 Prefoldin_2 PF01920.20 KFM67858.1 - 0.04 13.9 0.4 0.04 13.9 0.4 3.0 1 1 2 3 3 3 0 Prefoldin subunit DUF4907 PF16250.5 KFM67858.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) HTH_Tnp_Tc3_2 PF01498.18 KFM67860.1 - 5e-16 58.7 3.5 6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67860.1 - 3e-13 49.8 0.0 6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67860.1 - 2.1e-07 30.6 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67860.1 - 0.0027 17.5 0.6 0.0079 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67860.1 - 0.027 14.6 0.4 0.094 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM67860.1 - 2.3 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Pkinase PF00069.25 KFM67862.1 - 1.3e-50 172.3 0.0 1.5e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM67862.1 - 5.7e-31 107.7 0.0 6.8e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM67862.1 - 2.2e-05 23.4 0.0 3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFM67862.1 - 0.00035 20.0 0.1 0.00054 19.4 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM67862.1 - 0.0012 18.3 0.0 0.13 11.5 0.0 2.4 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 KFM67862.1 - 0.0075 16.2 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFM67862.1 - 0.055 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL IKBKB_SDD PF18397.1 KFM67863.1 - 2.6e-15 56.5 1.9 3.2e-15 56.2 1.9 1.1 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain IKBKB_SDD PF18397.1 KFM67864.1 - 9.8e-20 71.0 10.1 9.8e-20 71.0 10.1 1.4 2 0 0 2 2 2 1 IQBAL scaffold dimerization domain DUF484 PF04340.12 KFM67864.1 - 0.051 13.3 1.1 0.14 11.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF484 DUF1759 PF03564.15 KFM67865.1 - 3.6e-06 27.0 0.0 6.4e-06 26.2 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1725 PF08333.11 KFM67865.1 - 0.12 12.1 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) zf-H2C2_2 PF13465.6 KFM67866.1 - 6.6e-11 42.1 14.1 3.7e-07 30.3 2.3 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67866.1 - 7.3e-10 38.8 10.5 7.6e-05 22.9 2.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67866.1 - 2.3e-06 28.0 9.3 0.0098 16.7 2.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM67866.1 - 3.1e-06 26.8 14.6 1.2e-05 25.0 2.8 2.6 2 1 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM67866.1 - 0.0029 17.8 3.0 0.063 13.6 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM67866.1 - 0.021 15.1 3.4 2.3 8.6 0.8 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFM67866.1 - 0.097 13.0 0.8 0.22 11.8 0.8 1.5 1 1 1 2 2 2 0 BolA-like protein zf-met PF12874.7 KFM67866.1 - 0.14 12.6 6.5 0.46 10.9 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_7 PF15269.6 KFM67866.1 - 0.17 12.0 6.3 0.98 9.5 0.7 2.2 1 1 1 2 2 2 0 Zinc-finger zf-H2C2_2 PF13465.6 KFM67867.1 - 0.07 13.6 6.8 0.15 12.5 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger double domain AAA_12 PF13087.6 KFM67868.1 - 3.4e-38 131.3 0.6 1e-37 129.7 0.6 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM67868.1 - 1.9e-24 86.9 4.6 1.4e-23 84.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFM67868.1 - 5.3e-09 36.6 0.0 9.4e-08 32.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM67868.1 - 7e-07 29.2 0.0 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM67868.1 - 0.0051 17.1 1.2 0.23 11.7 0.0 4.0 4 0 0 4 4 4 1 AAA domain DUF2075 PF09848.9 KFM67868.1 - 0.0054 16.0 1.2 0.046 13.0 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFM67868.1 - 0.0084 16.1 0.5 0.087 12.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFM67868.1 - 0.047 13.1 0.1 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 KFM67868.1 - 0.41 10.0 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Maf PF02545.14 KFM67870.1 - 1.3e-27 96.7 0.0 1.4e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein START PF01852.19 KFM67871.1 - 3.6e-32 111.5 1.5 4.4e-32 111.2 0.2 1.8 2 0 0 2 2 2 1 START domain PH PF00169.29 KFM67871.1 - 6.8e-13 49.0 0.1 1.9e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFM67871.1 - 5.2e-08 33.1 0.1 1.3e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFM67871.1 - 2.6e-06 27.8 0.3 9.7e-05 22.8 0.3 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFM67871.1 - 0.12 12.6 0.0 0.46 10.8 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain Jiraiya PF15038.6 KFM67872.1 - 1.3e-09 37.7 0.2 1.6e-09 37.4 0.2 1.1 1 0 0 1 1 1 1 Jiraiya Jiraiya PF15038.6 KFM67873.1 - 1.7e-22 79.7 11.7 2.2e-22 79.3 11.7 1.1 1 0 0 1 1 1 1 Jiraiya HTH_Tnp_Tc3_2 PF01498.18 KFM67875.1 - 4.7e-16 58.8 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67875.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67875.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67875.1 - 0.0026 17.5 0.6 0.0076 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67875.1 - 0.03 14.4 0.4 0.091 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM67875.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM67876.1 - 4.7e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67876.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67876.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67876.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67876.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Exo_endo_phos PF03372.23 KFM67877.1 - 4.2e-17 62.4 0.0 8.9e-15 54.8 0.0 2.6 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family zf-met PF12874.7 KFM67879.1 - 9.5e-28 95.7 32.6 8.9e-08 32.3 0.4 6.5 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM67879.1 - 1.2e-22 79.6 34.0 2.7e-06 27.5 1.0 6.5 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM67879.1 - 1.1e-17 64.2 40.8 0.00042 20.6 2.8 6.1 1 1 5 6 6 6 6 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFM67879.1 - 1.5e-14 53.5 32.1 0.00091 19.6 0.2 7.0 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67879.1 - 1.7e-14 53.3 21.9 0.047 14.5 0.3 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger C1_2 PF03107.16 KFM67879.1 - 0.00039 20.7 15.4 1.3 9.4 0.1 6.2 6 0 0 6 6 6 1 C1 domain Trm112p PF03966.16 KFM67879.1 - 0.023 15.3 4.7 0.74 10.4 0.1 3.6 3 1 0 3 3 3 0 Trm112p-like protein zf-DBF PF07535.12 KFM67879.1 - 0.047 13.8 35.2 0.37 10.9 1.2 6.0 6 0 0 6 6 6 0 DBF zinc finger YebO PF13974.6 KFM67879.1 - 0.22 11.6 0.0 0.22 11.6 0.0 3.8 4 0 0 4 4 4 0 YebO-like protein GP24_25 PF17388.2 KFM67879.1 - 0.26 11.3 16.7 3 7.8 3.5 4.3 3 1 1 4 4 4 0 Tail assembly gene products 24 & 25 zf-C2H2_3rep PF18868.1 KFM67879.1 - 0.67 10.6 18.0 25 5.6 0.1 5.3 1 1 5 6 6 6 0 Zinc finger C2H2-type, 3 repeats BTB_2 PF02214.22 KFM67879.1 - 0.79 10.1 4.0 0.32 11.4 0.3 2.1 2 0 0 2 2 2 0 BTB/POZ domain VATC PF18716.1 KFM67879.1 - 1.2 9.0 20.0 13 5.8 0.2 5.7 6 0 0 6 6 6 0 Vms1-associating treble clef domain Rep_fac-A_C PF08646.10 KFM67879.1 - 1.8 8.3 13.8 2 8.1 0.4 4.6 5 1 0 5 5 5 0 Replication factor-A C terminal domain PyrI_C PF02748.15 KFM67879.1 - 2.1 8.3 13.4 14 5.7 0.2 4.8 5 0 0 5 5 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 KFM67879.1 - 7.5 6.8 18.7 11 6.3 0.1 5.6 6 0 0 6 6 6 0 Zinc ribbon domain DDE_Tnp_1_7 PF13843.6 KFM67881.1 - 4.1e-29 102.0 0.1 4.7e-29 101.8 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 Arf PF00025.21 KFM67882.1 - 7.2e-23 80.9 0.1 8.7e-23 80.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFM67882.1 - 6.5e-07 29.6 0.0 1.7e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFM67882.1 - 1.6e-06 27.6 0.5 7.5e-06 25.3 0.5 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 KFM67882.1 - 1.4e-05 24.7 0.0 2.2e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KFM67882.1 - 0.00014 21.8 0.2 0.29 11.0 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFM67882.1 - 0.00033 20.2 0.4 0.0011 18.4 0.4 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KFM67882.1 - 0.00037 20.8 0.1 0.00083 19.6 0.0 1.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 KFM67882.1 - 0.0021 18.5 0.0 0.0032 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 KFM67882.1 - 0.0034 17.2 0.0 0.24 11.1 0.1 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KFM67882.1 - 0.0062 16.3 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFM67882.1 - 0.0065 16.5 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KFM67882.1 - 0.0086 15.7 0.1 3 7.4 0.0 2.3 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KFM67882.1 - 0.0087 15.6 1.3 0.65 9.5 1.3 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 KFM67882.1 - 0.021 15.0 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM67882.1 - 0.029 14.3 0.1 0.12 12.3 0.0 2.0 2 1 1 3 3 3 0 NACHT domain GTP_EFTU PF00009.27 KFM67882.1 - 0.03 13.9 0.1 0.063 12.8 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KFM67882.1 - 0.03 14.1 0.3 0.39 10.5 0.0 2.5 2 2 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 KFM67882.1 - 0.062 13.7 0.0 0.08 13.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFM67882.1 - 0.065 13.3 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFM67882.1 - 0.085 12.4 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region ThiS-like PF14453.6 KFM67882.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 ThiS-like ubiquitin AAA_28 PF13521.6 KFM67882.1 - 0.14 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFM67882.1 - 0.4 9.8 2.3 0.98 8.6 2.3 1.9 1 1 0 1 1 1 0 NB-ARC domain WD40 PF00400.32 KFM67883.1 - 4e-27 93.9 6.3 0.00028 21.6 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM67883.1 - 7.9e-09 35.7 0.1 0.00017 21.8 0.0 3.5 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM67883.1 - 0.021 14.2 0.1 0.2 10.9 0.0 2.3 1 1 2 3 3 3 0 WD40-like domain LRR_8 PF13855.6 KFM67884.1 - 6.9e-14 51.4 0.1 2.1e-06 27.4 0.0 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM67884.1 - 3.4e-05 24.1 0.1 0.00047 20.5 0.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM67884.1 - 0.0016 18.7 0.1 9.1 7.3 0.0 5.2 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_5 PF13306.6 KFM67884.1 - 0.0071 16.3 0.1 0.063 13.2 0.0 2.4 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) RRM_1 PF00076.22 KFM67886.1 - 2e-06 27.5 0.0 2.4e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM67886.1 - 0.0065 16.6 0.0 0.0083 16.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KFM67886.1 - 0.18 11.4 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_Tnp_Tc3_2 PF01498.18 KFM67887.1 - 8.8e-10 38.7 0.1 9.2e-10 38.6 0.1 1.0 1 0 0 1 1 1 1 Transposase DUF356 PF04009.12 KFM67887.1 - 0.071 13.4 0.0 0.072 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF356) DDE_3 PF13358.6 KFM67888.1 - 1.9e-06 27.7 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HIGH_NTase1 PF05636.11 KFM67888.1 - 0.059 12.6 0.0 0.065 12.4 0.0 1.0 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase CobA_CobO_BtuR PF02572.15 KFM67888.1 - 0.16 12.2 0.0 0.16 12.2 0.0 1.0 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP E1_DerP2_DerF2 PF02221.15 KFM67889.1 - 3.5e-10 40.4 0.0 4.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 ML domain CobS_N PF12556.8 KFM67889.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal DDE_3 PF13358.6 KFM67890.1 - 0.032 14.0 0.0 0.038 13.8 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease C1_1 PF00130.22 KFM67893.1 - 0.00012 21.8 14.5 0.023 14.6 5.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KFM67893.1 - 0.0015 18.1 1.1 0.0015 18.1 1.1 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KFM67893.1 - 0.25 11.3 7.6 0.14 12.1 3.3 2.5 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KFM67893.1 - 1.1 9.5 9.4 6.6 6.9 0.2 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain DAGK_cat PF00781.24 KFM67894.1 - 1.5e-30 105.4 0.0 2.3e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 KFM67894.1 - 6e-19 68.9 0.0 9.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain C1_1 PF00130.22 KFM67894.1 - 0.075 12.9 8.4 0.12 12.3 8.0 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD_kinase PF01513.21 KFM67894.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 ATP-NAD kinase HTH_Tnp_Tc3_2 PF01498.18 KFM67895.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67895.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67896.1 - 2.4e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67896.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67897.1 - 1.7e-16 60.2 2.4 7.2e-16 58.2 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67897.1 - 1.7e-13 50.5 0.0 3.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67897.1 - 3.2e-07 30.0 1.6 8.6e-07 28.6 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67897.1 - 0.0031 17.2 0.5 0.0092 15.7 0.5 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM67897.1 - 0.032 14.3 0.4 0.11 12.6 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM67897.1 - 7.8 7.2 17.5 0.15 12.7 1.9 3.5 3 1 1 4 4 4 0 Homeodomain-like domain EphA2_TM PF14575.6 KFM67898.1 - 0.036 14.9 0.2 0.29 12.0 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LIM PF00412.22 KFM67900.1 - 1.1e-06 28.8 4.8 1.8e-06 28.0 4.8 1.4 1 0 0 1 1 1 1 LIM domain RNA_pol_Rpc34 PF05158.12 KFM67901.1 - 4e-08 33.0 0.0 4.4e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RNA_pol_Rpc34 PF05158.12 KFM67902.1 - 7.4e-11 42.0 0.0 1.4e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit zf-H2C2_2 PF13465.6 KFM67903.1 - 3.8e-108 349.5 105.6 1.2e-08 35.0 0.1 16.3 16 0 0 16 16 16 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67903.1 - 1.1e-83 271.3 145.6 1.6e-06 28.2 0.8 15.7 16 0 0 16 16 16 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67903.1 - 7.8e-52 169.4 127.7 0.00022 21.8 0.7 15.4 15 0 0 15 15 15 15 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM67903.1 - 2e-48 161.5 114.5 2.1e-05 24.4 0.2 15.5 15 0 0 15 15 15 15 C2H2-type zinc finger zf-met PF12874.7 KFM67903.1 - 5.6e-40 134.6 118.2 0.00044 20.5 0.6 15.5 15 0 0 15 15 15 15 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM67903.1 - 6.5e-31 106.0 91.0 0.0021 18.3 0.1 15.4 15 0 0 15 15 15 13 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM67903.1 - 8.8e-09 35.0 32.6 0.074 12.9 0.2 9.5 4 3 7 11 11 11 4 GAGA factor zf-C2H2_2 PF12756.7 KFM67903.1 - 5.4e-08 33.1 97.6 0.051 13.9 15.3 11.5 2 1 8 11 11 11 6 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM67903.1 - 6.5e-08 32.2 90.6 0.12 12.1 0.1 14.0 14 0 0 14 14 14 8 C2H2-type zinc-finger domain DUF4712 PF15830.5 KFM67903.1 - 3.1e-06 27.1 1.6 0.0012 18.6 0.2 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4712) zf-C2HC_2 PF13913.6 KFM67903.1 - 0.0001 22.1 63.9 0.36 10.8 0.1 13.9 14 0 0 14 14 14 4 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 KFM67903.1 - 0.0001 23.0 56.5 0.027 15.1 1.3 10.4 5 4 2 9 9 9 3 Zinc finger C2H2-type, 3 repeats ADK_lid PF05191.14 KFM67903.1 - 0.00099 19.0 57.1 0.006 16.5 2.2 9.8 5 3 2 7 7 7 1 Adenylate kinase, active site lid Cyclase_polyket PF04673.12 KFM67903.1 - 0.035 14.4 0.1 6.2 7.1 0.0 3.7 3 0 0 3 3 3 0 Polyketide synthesis cyclase BolA PF01722.18 KFM67903.1 - 0.17 12.2 31.8 3.3 8.1 1.0 9.2 2 2 7 9 9 9 0 BolA-like protein DUF2256 PF10013.9 KFM67903.1 - 0.17 12.0 50.9 29 4.9 0.0 13.8 15 0 0 15 15 15 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFM67903.1 - 1.2 9.9 60.8 3.9 8.3 2.1 7.8 3 3 5 8 8 8 0 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM67903.1 - 1.3 8.9 66.8 1 9.2 2.9 12.6 8 5 6 14 14 13 0 C2H2 type zinc-finger (1 copy) Flag1_repress PF03614.13 KFM67903.1 - 4.8 6.9 12.4 27 4.5 0.4 4.5 2 1 2 5 5 5 0 Repressor of phase-1 flagellin Pkinase_Tyr PF07714.17 KFM67905.1 - 3e-07 30.0 0.1 4.3e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM67905.1 - 0.029 13.7 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KFM67906.1 - 2.2e-77 259.9 0.0 2.8e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM67906.1 - 1.1e-37 129.8 0.0 1.5e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KFM67906.1 - 0.00036 19.6 0.0 0.00056 19.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM67906.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Focal_AT PF03623.13 KFM67908.1 - 2.4e-21 76.1 4.2 3.3e-21 75.7 4.2 1.2 1 0 0 1 1 1 1 Focal adhesion targeting region Sortase PF04203.13 KFM67910.1 - 0.17 11.7 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Sortase domain HLH PF00010.26 KFM67911.1 - 6.1e-10 38.9 3.5 1.5e-09 37.7 3.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 KFM67911.1 - 0.06 13.0 12.8 0.11 12.1 12.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein eIF3_N PF09440.10 KFM67912.1 - 1.3e-39 135.7 1.7 3.2e-39 134.4 1.7 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KFM67912.1 - 6.1e-18 65.3 0.5 1.7e-17 63.9 0.1 2.0 2 0 0 2 2 2 1 PCI domain rve PF00665.26 KFM67913.1 - 3.7e-18 65.8 0.0 6.4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KFM67913.1 - 0.00045 19.9 0.1 0.0016 18.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 KFM67913.1 - 0.057 13.5 0.0 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM67914.1 - 7.7e-10 38.9 3.9 1.3e-09 38.2 3.9 1.3 1 0 0 1 1 1 1 Transposase Dimer_Tnp_hAT PF05699.14 KFM67916.1 - 3.2e-05 23.6 0.3 3.5e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-3CxxC PF13695.6 KFM67918.1 - 2.4e-16 60.0 0.2 2.7e-16 59.9 0.2 1.0 1 0 0 1 1 1 1 Zinc-binding domain Uteroglobin PF01099.17 KFM67919.1 - 0.044 14.1 0.0 0.05 13.9 0.0 1.1 1 0 0 1 1 1 0 Uteroglobin family DEAD PF00270.29 KFM67920.1 - 0.0007 19.4 0.0 0.00073 19.4 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM67920.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFM67921.1 - 2.1e-07 31.2 0.0 2.2e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KFM67923.1 - 6e-20 71.5 0.0 1.4e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFM67923.1 - 1.6e-18 66.9 0.2 4.4e-18 65.4 0.1 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold CTNNBL PF08216.11 KFM67923.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear Glyco_transf_49 PF13896.6 KFM67924.1 - 1.8e-10 40.7 0.1 1.9e-10 40.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan zf-CCHC_4 PF14392.6 KFM67925.1 - 0.42 10.4 15.1 0.41 10.4 1.7 2.7 3 0 0 3 3 3 0 Zinc knuckle PX PF00787.24 KFM67926.1 - 1.9e-27 95.5 0.0 2.3e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 PX domain HTH_Tnp_Tc3_2 PF01498.18 KFM67927.1 - 2.4e-16 59.7 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67927.1 - 9.6e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM67928.1 - 5.2e-16 58.7 3.5 6.1e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67928.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67928.1 - 2.7e-07 30.2 1.6 7.5e-07 28.8 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67928.1 - 0.0028 17.4 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67928.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-CCHC PF00098.23 KFM67931.1 - 1.1e-05 25.3 2.4 1.6e-05 24.8 2.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KFM67931.1 - 3.4e-05 23.6 0.7 8.1e-05 22.4 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle HSBP1 PF06825.12 KFM67931.1 - 0.054 13.4 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 GrpE PF01025.19 KFM67931.1 - 0.074 12.7 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 GrpE Erythro-docking PF09277.11 KFM67931.1 - 0.11 12.4 0.8 0.67 9.9 0.8 2.1 1 1 0 1 1 1 0 Erythronolide synthase, docking Spuma_A9PTase PF03539.14 KFM67932.1 - 0.15 12.2 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) BTB PF00651.31 KFM67933.1 - 1.2e-05 25.5 0.7 0.00057 20.1 0.1 3.1 2 1 1 3 3 3 1 BTB/POZ domain DDE_3 PF13358.6 KFM67935.1 - 0.005 16.6 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SVWC PF15430.6 KFM67937.1 - 1.6e-08 34.7 5.1 2e-08 34.4 5.1 1.2 1 0 0 1 1 1 1 Single domain von Willebrand factor type C HTH_Tnp_Tc3_2 PF01498.18 KFM67938.1 - 2e-16 60.0 2.2 4.5e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67938.1 - 9.5e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HBB PF06777.11 KFM67940.1 - 0.044 13.4 0.1 0.062 13.0 0.1 1.3 1 0 0 1 1 1 0 Helical and beta-bridge domain tRNA-synt_1c PF00749.21 KFM67941.1 - 1.5e-83 280.3 0.0 1.7e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain CNDH2_C PF16858.5 KFM67943.1 - 0.0066 16.4 8.3 0.0066 16.4 8.3 2.3 1 1 1 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term LMBR1 PF04791.16 KFM67943.1 - 0.027 13.4 5.7 0.05 12.5 5.7 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Ureidogly_lyase PF04115.12 KFM67943.1 - 0.25 11.1 6.5 0.74 9.6 0.2 2.9 3 1 1 4 4 4 0 Ureidoglycolate lyase zf-CpG_bind_C PF12269.8 KFM67943.1 - 9.5 5.9 15.5 0.13 12.0 5.8 2.6 2 1 1 3 3 3 0 CpG binding protein zinc finger C terminal domain Helicase_C PF00271.31 KFM67945.1 - 9.4e-20 71.0 0.1 1.5e-18 67.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFM67945.1 - 9.8e-06 24.5 0.1 1.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain RNaseH_like PF04308.12 KFM67945.1 - 0.043 13.7 0.4 0.091 12.7 0.4 1.5 1 0 0 1 1 1 0 Ribonuclease H-like TFIIF_beta PF02270.15 KFM67945.1 - 0.053 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain CLIP_1 PF18322.1 KFM67946.1 - 3.8e-14 52.5 3.5 9.5e-14 51.2 3.5 1.7 1 0 0 1 1 1 1 Serine protease Clip domain PPAF-2 Trypsin PF00089.26 KFM67946.1 - 1.9e-07 31.1 0.1 3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KFM67947.1 - 7.5e-54 182.9 0.0 1.5e-53 181.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM67947.1 - 4e-05 24.5 0.0 0.00011 23.2 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain CLIP_1 PF18322.1 KFM67947.1 - 0.00046 20.2 4.0 0.0015 18.6 4.0 1.9 1 1 0 1 1 1 1 Serine protease Clip domain PPAF-2 DUF1986 PF09342.11 KFM67947.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Glycophorin_A PF01102.18 KFM67948.1 - 0.0053 17.0 0.1 0.0085 16.3 0.1 1.4 1 1 0 1 1 1 1 Glycophorin A Syndecan PF01034.20 KFM67948.1 - 0.022 14.6 0.6 0.022 14.6 0.6 1.9 2 0 0 2 2 2 0 Syndecan domain DUF2892 PF11127.8 KFM67948.1 - 0.083 12.9 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF4690 PF15756.5 KFM67948.1 - 0.17 12.5 1.3 0.34 11.5 1.3 1.5 1 1 0 1 1 1 0 Small Novel Rich in Cartilage SPRY PF00622.28 KFM67949.1 - 2.8e-09 37.1 1.1 3.5e-08 33.6 0.0 2.6 3 0 0 3 3 3 1 SPRY domain Amidase PF01425.21 KFM67950.1 - 3.1e-11 42.9 0.0 3.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KFM67951.1 - 9.6e-55 186.3 0.1 1.2e-54 186.1 0.1 1.1 1 0 0 1 1 1 1 Amidase Transposase_24 PF03004.14 KFM67952.1 - 0.0037 17.4 1.5 0.0097 16.0 0.3 2.0 2 1 0 2 2 2 1 Plant transposase (Ptta/En/Spm family) FrhB_FdhB_C PF04432.13 KFM67952.1 - 0.015 15.1 1.3 0.025 14.4 1.3 1.6 1 1 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Eclosion PF04736.12 KFM67953.1 - 1.1e-07 31.5 2.2 1.5e-07 31.0 2.2 1.2 1 0 0 1 1 1 1 Eclosion hormone UBZ_FAAP20 PF15750.5 KFM67953.1 - 0.039 13.9 0.4 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger CxC4 PF18717.1 KFM67953.1 - 0.046 13.6 2.9 0.3 10.9 2.0 2.2 1 1 1 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases DUF3499 PF12005.8 KFM67954.1 - 0.72 10.5 6.6 1.4 9.5 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Str_synth PF03088.16 KFM67955.1 - 4.5e-25 87.6 0.1 9.6e-25 86.5 0.1 1.6 1 0 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 KFM67955.1 - 2.6e-12 46.9 0.0 1.7e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KFM67955.1 - 0.14 12.4 0.0 1.1 9.5 0.0 2.3 2 1 1 3 3 3 0 Arylesterase PQQ_3 PF13570.6 KFM67955.1 - 0.17 12.4 0.5 0.68 10.5 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain zf-C2H2 PF00096.26 KFM67956.1 - 4.9e-38 127.5 90.4 1.3e-06 28.5 0.7 12.7 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67956.1 - 2.5e-34 115.0 85.7 0.00041 20.9 0.3 12.7 13 0 0 13 13 13 11 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM67956.1 - 4.8e-25 86.8 86.0 1.6e-05 25.1 0.4 12.7 13 1 0 13 13 12 10 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM67956.1 - 1e-18 67.1 46.6 0.012 15.8 0.3 10.8 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM67956.1 - 5.3e-17 61.6 60.9 0.019 15.3 1.8 11.5 12 0 0 12 12 11 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM67956.1 - 2.6e-05 24.1 3.5 0.0012 18.8 1.9 11.1 12 0 0 12 12 12 5 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM67956.1 - 0.0001 22.6 63.5 0.14 12.5 0.4 9.3 1 1 9 10 10 10 5 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFM67956.1 - 0.0022 17.7 0.1 0.0022 17.7 0.1 10.3 11 0 0 11 11 11 4 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 KFM67956.1 - 0.026 14.2 2.9 0.026 14.2 2.9 8.3 5 3 5 10 10 10 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2180 PF09947.9 KFM67956.1 - 0.036 14.0 0.7 0.036 14.0 0.7 5.5 4 4 0 4 4 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-H2C2_5 PF13909.6 KFM67956.1 - 0.051 13.3 69.5 0.12 12.1 1.3 12.1 12 1 0 12 12 12 0 C2H2-type zinc-finger domain Zn-C2H2_12 PF18112.1 KFM67956.1 - 0.14 12.6 30.6 1.1 9.8 0.3 8.6 9 0 0 9 9 9 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 KFM67956.1 - 0.35 10.5 45.4 1.6 8.4 1.3 9.2 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 KFM67956.1 - 0.58 10.3 0.1 0.58 10.3 0.1 9.5 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4764 PF15961.5 KFM67956.1 - 1.5 7.4 19.8 0.5 9.0 0.7 3.9 2 1 1 4 4 4 0 Domain of unknown function (DUF4764) zinc_ribbon_15 PF17032.5 KFM67956.1 - 4.1 8.2 51.4 0.6 10.9 2.3 6.8 1 1 6 7 7 7 0 zinc-ribbon family Myb_DNA-bind_5 PF13873.6 KFM67958.1 - 9.4e-15 54.5 1.1 1.3e-14 54.0 1.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFM67958.1 - 8.7e-08 32.4 0.6 1.3e-07 31.9 0.6 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM67958.1 - 0.0012 19.1 0.1 0.0019 18.5 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 KFM67958.1 - 0.028 14.6 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3020 PF11223.8 KFM67958.1 - 1.8 9.2 6.4 0.3 11.6 2.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) zf-H2C2_2 PF13465.6 KFM67959.1 - 1.8e-56 186.2 69.6 1.5e-07 31.5 0.7 11.7 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67959.1 - 5.9e-49 161.9 84.1 8.4e-06 26.0 2.7 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67959.1 - 1.2e-44 147.0 81.3 0.0001 22.8 1.0 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM67959.1 - 1.7e-25 88.6 78.1 0.0044 17.4 1.2 11.2 11 0 0 11 11 11 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM67959.1 - 7.2e-23 80.3 79.6 0.0047 17.2 0.2 11.8 10 1 1 11 11 11 9 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM67959.1 - 1.3e-13 51.0 1.0 0.37 11.1 0.0 7.7 1 1 6 8 8 8 3 BolA-like protein zf-C2H2_6 PF13912.6 KFM67959.1 - 1.5e-10 40.8 83.4 0.0034 17.3 0.3 11.7 12 0 0 12 12 12 8 C2H2-type zinc finger zf-Di19 PF05605.12 KFM67959.1 - 1.4e-06 28.5 55.3 0.0067 16.7 1.8 6.6 3 1 2 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFM67959.1 - 1.6e-05 25.1 63.3 0.2 12.0 1.0 10.6 1 1 10 11 11 11 5 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM67959.1 - 0.00014 21.6 1.0 0.024 14.5 0.0 10.5 11 0 0 11 11 11 4 zinc-finger of a C2HC-type GAGA PF09237.11 KFM67959.1 - 0.00028 20.6 17.2 5.5 6.9 0.1 7.4 2 1 7 9 9 9 4 GAGA factor Zf_RING PF16744.5 KFM67959.1 - 0.00082 19.4 52.7 2.3 8.4 4.2 10.4 1 1 7 9 9 9 2 KIAA1045 RING finger zf-MYST PF17772.1 KFM67959.1 - 0.011 15.3 52.3 0.34 10.6 0.2 9.7 6 3 5 11 11 11 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFM67959.1 - 0.097 13.4 44.8 0.22 12.3 1.4 6.0 3 3 3 6 6 6 0 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM67959.1 - 0.68 9.8 37.7 3.7 7.5 0.1 9.1 6 2 4 10 10 10 0 C2H2 type zinc-finger (1 copy) S36_mt PF10937.8 KFM67960.1 - 5.1e-08 34.5 0.0 6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial HTH_Tnp_Tc3_2 PF01498.18 KFM67961.1 - 4.2e-09 36.5 1.4 6.5e-09 35.9 1.4 1.3 1 0 0 1 1 1 1 Transposase FA PF08736.11 KFM67963.1 - 5e-15 55.3 3.4 1.3e-14 53.9 3.4 1.8 1 1 0 1 1 1 1 FERM adjacent (FA) Guanylate_kin PF00625.21 KFM67965.1 - 2.3e-38 131.7 0.0 3.2e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_5 PF07728.14 KFM67965.1 - 0.027 14.5 0.0 0.074 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YHS PF04945.13 KFM67965.1 - 0.22 11.6 0.0 0.22 11.6 0.0 2.4 3 0 0 3 3 3 0 YHS domain Lipase_3 PF01764.25 KFM67967.1 - 7.7e-16 58.2 0.0 1.4e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) BTB PF00651.31 KFM67969.1 - 0.00059 20.1 0.0 0.011 16.0 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain Pox_A9 PF04835.12 KFM67969.1 - 0.031 14.4 0.1 0.079 13.1 0.1 1.7 1 0 0 1 1 1 0 A9 protein conserved region HTH_Mga PF08280.11 KFM67969.1 - 0.093 12.8 0.3 0.29 11.2 0.3 1.8 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain hGDE_central PF14702.6 KFM67970.1 - 6.7 6.3 10.1 13 5.4 10.1 1.5 1 1 0 1 1 1 0 Central domain of human glycogen debranching enzyme DDE_3 PF13358.6 KFM67972.1 - 3.4e-09 36.6 0.0 4.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.32 KFM67976.1 - 0.07 14.0 1.4 47 5.1 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat DGF-1_C PF11040.8 KFM67978.1 - 1.5 8.9 4.8 1 9.4 2.2 2.0 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2398 PF09661.10 KFM67979.1 - 0.033 13.5 0.0 0.038 13.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) EGF PF00008.27 KFM67980.1 - 8.4 6.8 19.9 0.48 10.8 9.5 2.8 3 0 0 3 3 3 0 EGF-like domain CD36 PF01130.21 KFM67982.1 - 6.3e-96 321.7 0.0 7.2e-96 321.5 0.0 1.0 1 0 0 1 1 1 1 CD36 family PorA PF11271.8 KFM67982.1 - 0.18 11.0 0.1 0.34 10.2 0.0 1.4 2 0 0 2 2 2 0 Porin PorA Peptidase_C5 PF00770.18 KFM67983.1 - 0.019 14.7 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Adenovirus endoprotease CD36 PF01130.21 KFM67983.1 - 0.038 12.5 0.2 0.048 12.2 0.2 1.1 1 0 0 1 1 1 0 CD36 family CD36 PF01130.21 KFM67984.1 - 2.8e-140 467.9 0.1 3.3e-140 467.7 0.1 1.0 1 0 0 1 1 1 1 CD36 family DUF5305 PF17231.2 KFM67984.1 - 0.36 10.2 4.7 0.42 10.0 0.3 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5305) DUF3040 PF11239.8 KFM67984.1 - 4 7.8 5.8 4.6 7.6 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Phage_holin_3_6 PF07332.11 KFM67984.1 - 6 6.9 9.0 15 5.6 1.3 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HTH_Tnp_Tc3_2 PF01498.18 KFM67985.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM67985.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.22 KFM67986.1 - 9.8e-18 63.8 0.1 2e-17 62.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM67986.1 - 0.0096 15.8 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KFM67986.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM67986.1 - 0.054 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif Ndc1_Nup PF09531.10 KFM67986.1 - 0.17 10.6 15.9 0.17 10.5 15.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 KFM67986.1 - 3.4 6.8 29.8 4.4 6.4 29.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 KFM67986.1 - 4.3 6.0 20.3 7.1 5.3 20.3 1.4 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 KFM67986.1 - 9.6 5.2 21.9 12 4.8 21.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ldl_recept_a PF00057.18 KFM67987.1 - 1.8e-08 34.5 4.6 5.5e-08 32.9 4.6 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 KFM67988.1 - 1.9e-07 31.2 10.2 4.8e-07 29.9 10.2 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFM67988.1 - 2.6e-05 24.5 0.0 5.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 CUB domain HTH_Tnp_Tc3_2 PF01498.18 KFM67989.1 - 5.2e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM67989.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM67989.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM67989.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM67989.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Frizzled PF01534.17 KFM67990.1 - 9.4e-100 333.8 21.6 1.4e-99 333.2 21.6 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFM67990.1 - 4.8e-23 81.9 1.8 4.8e-23 81.9 1.8 2.0 2 0 0 2 2 2 1 Fz domain DUF373 PF04123.13 KFM67990.1 - 4.5 6.6 8.5 0.21 11.0 0.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Histone PF00125.24 KFM67991.1 - 7.4e-53 178.4 1.7 9.1e-53 178.1 1.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KFM67991.1 - 5e-05 23.6 0.0 8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFM67991.1 - 0.00036 20.6 0.5 0.0009 19.3 0.0 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFM67991.1 - 0.0022 18.6 1.7 0.0033 18.0 1.7 1.3 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KFM67991.1 - 0.0039 17.4 0.1 0.0086 16.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2408 PF10303.9 KFM67991.1 - 0.09 13.3 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) zf-H2C2_2 PF13465.6 KFM67992.1 - 1.8e-48 160.9 83.0 1.1e-08 35.1 0.9 10.5 10 1 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67992.1 - 1.1e-41 139.0 90.0 3e-05 24.2 2.0 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67992.1 - 6.2e-26 88.8 79.6 0.00084 20.0 1.1 9.4 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM67992.1 - 7.5e-25 86.4 73.5 1.1e-08 34.8 1.2 9.4 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM67992.1 - 1.1e-16 60.6 57.2 0.026 14.9 0.2 9.5 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM67992.1 - 2.2e-10 40.6 59.1 0.0021 18.3 0.3 9.1 8 1 1 9 9 9 7 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFM67992.1 - 0.00017 21.1 47.1 0.62 9.7 0.1 9.1 9 0 0 9 9 9 3 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 KFM67992.1 - 0.00038 20.4 36.7 0.0096 15.9 1.9 6.2 4 2 1 5 5 5 2 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 KFM67992.1 - 0.00045 20.3 31.6 0.17 12.0 1.7 5.8 4 2 1 5 5 5 4 Zinc ribbon domain zf-H2C2_5 PF13909.6 KFM67992.1 - 0.0073 16.0 0.7 0.0073 16.0 0.7 9.5 10 0 0 10 10 9 4 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 KFM67992.1 - 0.015 15.1 36.2 0.63 9.9 0.1 8.1 4 2 5 9 9 9 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM67992.1 - 0.038 13.9 37.7 1.5 8.8 0.5 9.1 9 0 0 9 9 9 0 zinc-finger of a C2HC-type HNH_5 PF14279.6 KFM67992.1 - 1 9.2 42.3 4 7.4 6.5 8.2 7 2 0 7 7 7 0 HNH endonuclease zinc_ribbon_15 PF17032.5 KFM67992.1 - 1.2 9.9 40.6 12 6.7 3.6 5.1 1 1 5 6 6 6 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 KFM67992.1 - 2.6 8.7 38.5 7 7.3 2.5 7.8 4 2 2 7 7 7 0 Zinc finger C2H2-type, 3 repeats DUF2225 PF09986.9 KFM67992.1 - 5.6 6.6 40.6 0.9 9.2 5.3 6.9 6 1 1 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_2 PF13465.6 KFM67993.1 - 4.7e-67 219.6 100.1 1e-09 38.4 3.1 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67993.1 - 1.4e-39 132.3 110.3 4.2e-05 23.8 0.3 11.2 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67993.1 - 5.5e-32 107.7 102.4 0.0013 19.4 0.2 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM67993.1 - 8.9e-20 70.2 90.0 0.00039 20.3 1.6 12.0 12 0 0 12 12 12 10 C2H2-type zinc finger zf-met PF12874.7 KFM67993.1 - 1.4e-16 60.3 91.3 0.0043 17.4 0.5 11.3 11 0 0 11 11 11 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM67993.1 - 5.3e-13 48.9 72.4 0.013 15.7 0.6 11.6 10 1 1 11 11 11 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM67993.1 - 6e-07 29.1 76.2 0.0049 16.6 0.2 11.7 11 0 0 11 11 11 7 C2H2-type zinc-finger domain BolA PF01722.18 KFM67993.1 - 1.2e-06 28.6 18.0 0.57 10.5 0.3 7.6 1 1 7 8 8 8 2 BolA-like protein zf-C2H2_11 PF16622.5 KFM67993.1 - 0.00093 18.9 0.6 0.00093 18.9 0.6 9.7 11 0 0 11 11 11 4 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM67993.1 - 0.0017 18.2 44.5 3.9 7.5 0.2 10.0 10 0 0 10 10 10 4 zinc-finger of a C2HC-type BHD_1 PF10403.9 KFM67993.1 - 0.0034 17.2 3.0 9.8 6.1 0.0 5.3 5 1 1 6 6 6 1 Rad4 beta-hairpin domain 1 zf-C2H2_2 PF12756.7 KFM67993.1 - 0.091 13.1 83.8 0.23 11.8 1.4 10.0 1 1 6 8 8 8 0 C2H2 type zinc-finger (2 copies) Complex1_49kDa PF00346.19 KFM67993.1 - 0.19 10.8 0.4 11 5.0 0.0 2.7 2 1 1 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DDE_Tnp_4 PF13359.6 KFM67994.1 - 5.8e-28 97.6 0.0 6.3e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM67994.1 - 3.5e-05 23.5 0.0 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFM67994.1 - 0.00024 20.8 0.0 0.0038 16.9 0.0 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 KFM67994.1 - 0.092 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain zf-H2C2_2 PF13465.6 KFM67995.1 - 8.9e-61 199.8 95.6 1.2e-07 31.9 0.1 16.0 16 0 0 16 16 16 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM67995.1 - 2.5e-56 185.1 118.3 6.1e-06 26.4 0.5 15.3 15 0 0 15 15 15 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM67995.1 - 2.6e-35 118.0 114.9 0.0064 17.2 1.0 15.8 16 0 0 16 16 16 14 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM67995.1 - 2.2e-20 72.1 96.0 0.0048 16.9 1.9 14.7 14 1 0 14 14 14 10 C2H2-type zinc finger zf-met PF12874.7 KFM67995.1 - 2.2e-14 53.3 98.2 0.00065 20.0 0.1 14.5 14 0 0 14 14 14 9 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFM67995.1 - 6e-10 38.5 55.0 0.043 13.4 0.1 13.0 13 0 0 13 13 13 4 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFM67995.1 - 5.8e-07 29.6 92.2 0.1 12.9 3.1 14.1 12 2 2 14 14 14 7 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM67995.1 - 7.8e-07 29.0 41.5 0.097 12.7 0.0 8.7 4 4 5 9 9 9 4 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM67995.1 - 0.00056 20.2 95.5 0.012 16.0 6.6 10.6 1 1 10 11 11 11 4 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.6 KFM67995.1 - 0.0024 17.7 59.4 0.36 10.7 3.0 12.0 8 4 2 10 10 10 4 HNH endonuclease Rho_N PF07498.12 KFM67995.1 - 0.065 13.2 0.6 95 3.1 0.0 4.6 4 1 0 4 4 4 0 Rho termination factor, N-terminal domain zf-RRPl_C4 PF17026.5 KFM67995.1 - 0.077 13.1 60.7 0.074 13.2 3.7 6.9 1 1 6 7 7 7 0 Putative ribonucleoprotein zinc-finger pf C4 type PEX-2N PF09263.10 KFM67995.1 - 0.13 12.6 0.8 36 4.8 0.0 3.5 3 0 0 3 3 3 0 Peroxisome biogenesis factor 1, N-terminal zf-C2H2_9 PF16293.5 KFM67995.1 - 0.13 12.1 0.2 0.13 12.1 0.2 11.6 8 5 6 14 14 14 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM67995.1 - 0.21 12.3 55.4 0.34 11.7 4.4 7.9 4 2 4 8 8 8 0 zinc-ribbon family Endonuclease_7 PF02945.15 KFM67995.1 - 0.28 11.1 74.1 0.5 10.3 12.8 8.6 2 2 2 5 5 5 0 Recombination endonuclease VII Cag12 PF13117.6 KFM67995.1 - 0.58 10.7 2.6 45 4.7 0.1 3.7 3 0 0 3 3 3 0 Cag pathogenicity island protein Cag12 Chal_sti_synt_N PF00195.19 KFM67995.1 - 2.2 7.6 6.2 1.2 8.5 0.2 2.9 1 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain GAGA PF09237.11 KFM67995.1 - 2.7 7.9 25.8 5.1 7.0 0.1 8.0 4 2 5 10 10 10 0 GAGA factor zf-C2H2 PF00096.26 KFM67999.1 - 9.9e-61 199.0 124.6 6.3e-06 26.4 0.5 14.6 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM67999.1 - 1.6e-60 199.0 107.5 6.9e-08 32.6 2.4 16.7 17 1 0 17 17 17 13 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM67999.1 - 4.1e-39 129.9 119.2 0.0064 17.2 3.1 15.2 15 0 0 15 15 15 14 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM67999.1 - 4.9e-22 77.4 99.5 4.9e-05 23.2 4.0 14.3 14 1 0 14 14 14 11 C2H2-type zinc finger zf-met PF12874.7 KFM67999.1 - 2e-20 72.5 105.1 8.5e-05 22.8 0.1 14.6 14 0 0 14 14 14 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM67999.1 - 1.3e-09 38.0 98.4 0.022 15.1 0.6 14.2 12 2 2 14 14 14 8 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM67999.1 - 2e-07 30.8 42.5 0.054 13.5 0.1 8.5 5 3 4 9 9 9 5 Adenylate kinase, active site lid zf_UBZ PF18439.1 KFM67999.1 - 6.1e-05 22.5 67.5 0.1 12.2 0.2 12.9 14 0 0 14 14 14 4 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM67999.1 - 0.00053 20.1 59.0 0.035 14.2 4.6 7.1 1 1 5 6 6 6 2 Putative ribonucleoprotein zinc-finger pf C4 type Rho_N PF07498.12 KFM67999.1 - 0.011 15.6 0.7 11 6.0 0.0 4.6 5 0 0 5 5 5 0 Rho termination factor, N-terminal domain YorP PF09629.10 KFM67999.1 - 0.069 13.3 10.5 3.6 7.8 0.1 5.1 3 2 2 5 5 5 0 YorP protein zinc_ribbon_15 PF17032.5 KFM67999.1 - 0.081 13.7 62.3 2 9.2 1.9 8.0 2 2 5 8 8 8 0 zinc-ribbon family Chal_sti_synt_N PF00195.19 KFM67999.1 - 0.086 12.3 0.2 0.086 12.3 0.2 3.0 1 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain zf-C2H2_2 PF12756.7 KFM67999.1 - 0.11 12.8 99.5 0.45 10.9 4.2 10.3 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.6 KFM67999.1 - 3.3 7.6 67.6 0.13 12.1 2.7 11.2 8 5 3 11 11 10 0 HNH endonuclease zf-H2C2_2 PF13465.6 KFM68000.1 - 2.2e-92 299.7 105.0 3.6e-08 33.5 0.1 14.0 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68000.1 - 8.3e-49 161.4 124.8 3.1e-05 24.2 1.1 13.5 13 1 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68000.1 - 1.3e-39 131.4 114.4 0.00098 19.8 0.4 13.1 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM68000.1 - 1.9e-29 101.1 95.8 0.0019 18.5 1.2 13.3 13 0 0 13 13 13 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM68000.1 - 1.2e-17 63.7 72.0 0.017 15.4 0.4 12.9 13 0 0 13 13 13 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM68000.1 - 6.3e-11 42.0 103.8 0.00019 21.3 0.3 14.0 14 0 0 14 14 14 8 C2H2-type zinc finger GAGA PF09237.11 KFM68000.1 - 1.1e-06 28.3 31.0 1.5 8.7 0.3 10.5 1 1 12 13 13 13 2 GAGA factor BolA PF01722.18 KFM68000.1 - 3.4e-06 27.2 16.2 0.47 10.8 0.0 6.7 3 3 3 6 6 6 2 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM68000.1 - 5.5e-06 26.3 40.7 2.5 8.2 0.1 11.9 8 3 5 13 13 13 1 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM68000.1 - 3e-05 23.8 55.9 4.5 7.2 0.2 12.6 3 3 10 13 13 13 2 C2H2 type zinc-finger (1 copy) DUF4825 PF16107.5 KFM68000.1 - 0.00025 21.1 0.2 4.7 7.4 0.0 5.4 2 2 5 7 7 7 1 Domain of unknown function (DUF4825) zf-C2H2_2 PF12756.7 KFM68000.1 - 0.00029 21.1 84.4 0.18 12.1 1.2 12.0 1 1 10 12 12 12 6 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM68000.1 - 0.00073 19.6 43.4 7.6 6.7 0.1 11.8 12 0 0 12 12 12 1 Uncharacterized protein conserved in bacteria (DUF2256) Baculo_IE-1 PF05290.11 KFM68000.1 - 0.0039 17.2 40.5 0.9 9.5 6.6 7.6 1 1 4 6 6 6 2 Baculovirus immediate-early protein (IE-0) zf-C2HC_2 PF13913.6 KFM68000.1 - 0.055 13.4 44.3 1.7 8.6 0.5 10.2 11 0 0 11 11 10 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM68000.1 - 0.12 13.2 47.6 5 7.9 1.0 6.7 3 2 4 7 7 7 0 zinc-ribbon family zf-DBF PF07535.12 KFM68000.1 - 0.35 11.0 56.1 0.73 10.0 0.7 10.5 11 0 0 11 11 11 0 DBF zinc finger TRAF6_Z2 PF18048.1 KFM68000.1 - 0.58 10.3 54.2 0.51 10.5 0.2 11.0 12 0 0 12 12 11 0 TNF receptor-associated factor 6 zinc finger 2 Zf_RING PF16744.5 KFM68000.1 - 4 7.6 62.5 3.8 7.7 0.6 11.7 1 1 10 11 11 11 0 KIAA1045 RING finger zf-RRPl_C4 PF17026.5 KFM68000.1 - 6.1 7.0 48.7 2 8.5 2.1 5.8 1 1 3 5 5 4 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 KFM68000.1 - 7.7 6.5 67.8 0.86 9.5 2.4 10.3 2 2 10 12 12 12 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YqaJ PF09588.10 KFM68002.1 - 3.8e-14 53.1 0.0 6.2e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain DDE_Tnp_4 PF13359.6 KFM68003.1 - 1.7e-40 138.3 0.0 3.3e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease THAP PF05485.12 KFM68003.1 - 1.7e-11 44.9 2.3 4e-11 43.7 2.3 1.7 1 0 0 1 1 1 1 THAP domain HTH_Tnp_4 PF13613.6 KFM68003.1 - 2.8e-10 39.7 0.3 5e-10 38.9 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KFM68003.1 - 1.5e-05 24.7 0.0 4.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 KFM68003.1 - 0.00045 20.5 0.7 0.0015 18.8 0.1 2.1 2 0 0 2 2 2 1 Transposase DDE domain RIH_assoc PF08454.11 KFM68003.1 - 0.026 14.4 0.5 0.071 13.0 0.5 1.7 1 0 0 1 1 1 0 RyR and IP3R Homology associated Pkinase PF00069.25 KFM68004.1 - 4.8e-142 472.0 0.0 8.7e-70 235.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM68004.1 - 5.7e-77 258.5 0.0 1.6e-40 139.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFM68004.1 - 7.5e-13 48.4 0.0 3.5e-06 26.6 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KFM68004.1 - 8.1e-12 44.9 0.0 5.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFM68004.1 - 8.6e-09 34.7 0.0 0.0027 16.5 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 KFM68004.1 - 2.1e-07 31.1 0.0 0.028 14.3 0.0 3.4 2 1 2 4 4 4 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFM68004.1 - 3.2e-06 26.8 0.0 0.00071 19.1 0.0 2.5 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pkinase_C PF00433.24 KFM68004.1 - 8.7e-06 26.3 1.4 3.1e-05 24.6 1.4 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 KFM68004.1 - 2.2e-05 24.2 0.4 3.5 7.2 0.0 4.2 4 0 0 4 4 4 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFM68004.1 - 0.00063 18.8 0.6 0.026 13.5 0.1 2.7 2 1 1 3 3 3 1 Haspin like kinase domain RIO1 PF01163.22 KFM68004.1 - 0.0013 18.4 1.3 0.031 13.9 0.2 2.7 3 1 0 3 3 3 1 RIO1 family DUF1258 PF06869.12 KFM68004.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Amidohydro_1 PF01979.20 KFM68005.1 - 6.8e-30 104.5 0.0 1.5e-29 103.4 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFM68005.1 - 9.9e-13 48.4 0.4 6.6e-06 25.9 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 KFM68005.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase HTH_Tnp_Tc3_2 PF01498.18 KFM68006.1 - 2.3e-14 53.4 1.0 5.9e-14 52.1 1.0 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68006.1 - 7.9e-14 51.6 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease ANF_receptor PF01094.28 KFM68007.1 - 0.00022 20.5 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region DDE_3 PF13358.6 KFM68008.1 - 5.6e-16 58.6 0.1 6.2e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68008.1 - 7.2e-16 58.2 6.5 1.5e-15 57.1 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68008.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68008.1 - 0.0027 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68008.1 - 0.016 15.4 0.1 0.068 13.3 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68008.1 - 0.037 14.1 2.6 0.037 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Suv3_N PF18114.1 KFM68009.1 - 1e-18 67.5 0.5 2.5e-18 66.3 0.5 1.7 1 0 0 1 1 1 1 Suv3 helical N-terminal domain SUV3_C PF12513.8 KFM68009.1 - 4.7e-16 58.4 0.1 2.9e-15 55.9 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 KFM68009.1 - 6e-15 54.8 0.4 1.2e-14 53.8 0.4 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 KFM68009.1 - 6.4e-12 45.8 0.0 1.8e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain P4Ha_N PF08336.11 KFM68009.1 - 0.042 13.9 2.1 0.081 12.9 2.1 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Prp19 PF08606.11 KFM68009.1 - 0.16 12.0 0.2 0.35 10.9 0.2 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like Synaptobrevin PF00957.21 KFM68009.1 - 0.21 11.4 1.0 0.42 10.4 1.0 1.5 1 0 0 1 1 1 0 Synaptobrevin PTEN_C2 PF10409.9 KFM68010.1 - 3.2e-19 69.0 0.0 4.3e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 KFM68010.1 - 2.3e-06 27.5 0.0 4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM68010.1 - 0.0008 19.0 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM68010.1 - 0.003 17.6 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM68010.1 - 0.038 14.1 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate PC4 PF02229.16 KFM68012.1 - 3e-06 26.8 0.0 4.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Alpha-amylase PF00128.24 KFM68013.1 - 2.2e-14 53.8 0.1 2.9e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DDE_3 PF13358.6 KFM68015.1 - 3.1e-06 27.0 0.0 6.5e-06 26.0 0.0 1.5 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_48 PF17906.1 KFM68018.1 - 0.00012 22.1 0.2 0.00021 21.3 0.2 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM68018.1 - 0.008 16.8 0.0 0.047 14.3 0.0 2.1 1 1 0 1 1 1 1 Homeodomain-like domain DUF4978 PF16349.5 KFM68019.1 - 0.18 11.4 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4978) Sigma70_ECF PF07638.11 KFM68020.1 - 0.11 12.4 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor THAP PF05485.12 KFM68023.1 - 3.3e-08 34.3 5.8 8.8e-08 33.0 5.8 1.8 1 0 0 1 1 1 1 THAP domain KorB_C PF06613.11 KFM68023.1 - 0.00081 19.3 0.4 71 3.5 0.0 5.7 4 3 2 6 6 6 0 KorB C-terminal beta-barrel domain protein_MS5 PF04776.12 KFM68023.1 - 0.17 12.0 13.2 1.5 9.0 2.2 3.6 1 1 3 4 4 4 0 Protein MS5 VraX PF17412.2 KFM68023.1 - 3 7.6 14.5 62 3.3 0.3 6.4 2 1 7 9 9 9 0 Family of unknown function Herpes_UL95 PF03038.14 KFM68023.1 - 5.7 6.0 9.7 12 4.9 0.4 3.7 1 1 0 2 2 2 0 UL95 family DDE_3 PF13358.6 KFM68024.1 - 6.1e-16 58.5 0.1 6.5e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68024.1 - 7.7e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68024.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68024.1 - 0.0027 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68024.1 - 0.017 15.3 0.1 0.067 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68024.1 - 0.036 14.1 2.6 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix AA_permease_2 PF13520.6 KFM68025.1 - 5.5e-45 154.0 37.7 5.5e-45 154.0 37.7 2.2 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFM68025.1 - 1.9e-29 102.6 31.4 1.9e-29 102.6 31.4 2.0 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFM68025.1 - 1.6e-18 66.5 5.3 1.6e-18 66.5 5.3 3.3 3 0 0 3 3 3 1 C-terminus of AA_permease zf-H2C2_2 PF13465.6 KFM68027.1 - 3.9e-08 33.4 1.0 3.9e-08 33.4 1.0 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68027.1 - 6.3e-05 23.2 6.5 6.3e-05 23.2 6.5 1.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68027.1 - 0.0013 19.3 3.9 0.0013 19.3 3.9 1.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM68027.1 - 0.037 14.1 5.1 0.11 12.5 5.1 1.9 1 1 0 1 1 1 0 C2H2-type zinc finger c-SKI_SMAD_bind PF08782.10 KFM68027.1 - 0.037 14.2 2.4 0.039 14.2 2.4 1.1 1 0 0 1 1 1 0 c-SKI Smad4 binding domain zf-met PF12874.7 KFM68027.1 - 0.038 14.4 2.5 0.038 14.4 2.5 1.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFM68028.1 - 4.7e-15 55.2 2.7 1.5e-08 34.7 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68028.1 - 5.2e-10 39.2 10.5 2.6e-06 27.6 1.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68028.1 - 1.6e-07 31.5 9.6 0.00016 22.2 1.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM68028.1 - 2.5e-07 30.5 5.5 0.0054 16.7 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM68028.1 - 0.00022 21.4 5.2 0.0086 16.3 0.6 2.7 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM68028.1 - 0.00033 20.9 4.5 0.0011 19.3 1.2 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type FYVE PF01363.21 KFM68028.1 - 0.003 17.7 5.8 0.004 17.3 5.8 1.2 1 1 0 1 1 1 1 FYVE zinc finger zf_UBZ PF18439.1 KFM68028.1 - 0.0032 17.0 3.7 0.93 9.1 0.6 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger C5HCH PF17982.1 KFM68028.1 - 0.0035 17.5 2.8 1.2 9.3 0.3 2.2 2 0 0 2 2 2 2 NSD Cys-His rich domain zf-C2HC_2 PF13913.6 KFM68028.1 - 0.0037 17.1 6.2 0.15 12.0 0.3 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type XPA_N PF01286.18 KFM68028.1 - 0.0052 16.8 3.8 0.51 10.4 0.6 2.4 2 0 0 2 2 2 2 XPA protein N-terminal DZR PF12773.7 KFM68028.1 - 0.023 14.7 0.8 0.032 14.2 0.8 1.2 1 0 0 1 1 1 0 Double zinc ribbon VATC PF18716.1 KFM68028.1 - 0.05 13.5 4.1 1.4 8.9 0.2 2.2 2 0 0 2 2 2 0 Vms1-associating treble clef domain C1_4 PF07975.12 KFM68028.1 - 0.055 13.7 7.5 0.079 13.2 6.9 1.6 1 1 1 2 2 2 0 TFIIH C1-like domain ADK_lid PF05191.14 KFM68028.1 - 0.081 12.9 2.7 4.2 7.4 3.2 2.3 1 1 1 2 2 2 0 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KFM68028.1 - 0.082 13.0 1.3 6 7.0 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger IBR PF01485.21 KFM68028.1 - 0.39 11.0 6.3 1.4 9.2 6.3 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_11 PF16622.5 KFM68028.1 - 3.6 7.4 9.8 0.88 9.4 0.9 2.4 2 1 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KFM68029.1 - 4.3e-74 241.9 83.8 1.4e-09 38.0 1.0 12.1 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68029.1 - 1.7e-49 163.6 102.7 9.2e-07 29.0 2.1 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68029.1 - 3.8e-38 126.9 97.2 0.00046 20.8 0.4 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM68029.1 - 8.8e-21 73.6 86.2 8.5e-05 22.8 0.8 11.5 11 0 0 11 11 11 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM68029.1 - 1.9e-17 62.8 76.9 0.00067 19.6 0.1 12.6 11 2 0 11 11 11 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM68029.1 - 1.7e-14 53.7 67.3 0.022 15.1 0.1 11.5 10 1 1 11 11 11 8 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM68029.1 - 2.9e-10 40.3 16.8 0.044 14.1 0.2 6.9 1 1 6 7 7 7 4 BolA-like protein zf-H2C2_5 PF13909.6 KFM68029.1 - 4.7e-07 29.4 85.2 0.0056 16.4 0.0 11.2 12 0 0 12 12 11 7 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM68029.1 - 0.00051 20.3 70.7 1 9.7 0.8 9.1 1 1 7 9 9 9 6 C2H2 type zinc-finger (2 copies) Baculo_IE-1 PF05290.11 KFM68029.1 - 0.045 13.7 34.6 4.9 7.1 0.1 8.6 1 1 6 8 8 8 0 Baculovirus immediate-early protein (IE-0) zf-C2HC_2 PF13913.6 KFM68029.1 - 0.06 13.3 40.2 4.7 7.2 0.1 10.1 11 0 0 11 11 11 0 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM68029.1 - 0.071 13.2 35.4 0.21 11.7 0.3 9.3 8 3 2 10 10 10 0 Sec23/Sec24 zinc finger PHF5 PF03660.14 KFM68029.1 - 0.091 13.0 30.2 0.3 11.3 1.8 5.1 1 1 4 6 6 6 0 PHF5-like protein zf-C2H2_11 PF16622.5 KFM68029.1 - 1.2 8.9 0.0 0.46 10.3 0.3 9.7 10 0 0 10 10 10 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KFM68030.1 - 1e-43 145.9 29.2 1.4e-09 38.0 0.7 6.1 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68030.1 - 8.8e-28 95.2 40.4 5.6e-05 23.4 0.7 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68030.1 - 1.3e-22 78.6 36.9 0.00075 20.1 0.6 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 KFM68030.1 - 8.5e-16 57.8 32.3 0.0034 17.7 0.5 6.2 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM68030.1 - 1.8e-13 50.1 31.7 0.0049 16.8 0.1 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM68030.1 - 6e-10 38.7 18.1 0.0032 17.2 0.2 5.5 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM68030.1 - 2.9e-09 37.0 27.4 0.029 14.7 0.4 6.2 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM68030.1 - 4e-08 32.9 10.0 0.78 9.6 0.1 5.5 1 1 5 6 6 6 3 GAGA factor zf-C2H2_9 PF16293.5 KFM68030.1 - 5.5e-05 22.9 18.9 0.84 9.5 0.1 5.3 2 2 4 6 6 6 2 C2H2 type zinc-finger (1 copy) zf-CHCC PF10276.9 KFM68030.1 - 6.5e-05 22.9 1.7 66 3.7 0.0 5.7 6 0 0 6 6 6 0 Zinc-finger domain BolA PF01722.18 KFM68030.1 - 0.00011 22.4 0.8 4.8 7.5 0.0 3.5 1 1 2 3 3 3 1 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM68030.1 - 0.00079 19.4 20.7 0.56 10.3 0.4 5.8 5 1 1 6 6 6 2 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM68030.1 - 0.00094 19.3 21.6 0.93 9.7 0.2 5.7 6 0 0 6 6 5 1 DBF zinc finger zf-C2H2_2 PF12756.7 KFM68030.1 - 0.0015 18.8 31.6 1.1 9.6 0.5 5.6 1 1 4 5 5 5 3 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM68030.1 - 0.0025 18.5 17.3 0.76 10.6 0.6 3.1 2 1 1 3 3 3 3 zinc-ribbon family zf-FPG_IleRS PF06827.14 KFM68030.1 - 0.0025 17.6 13.9 15 5.6 0.1 6.0 6 0 0 6 6 6 0 Zinc finger found in FPG and IleRS C1_1 PF00130.22 KFM68030.1 - 0.0084 16.0 27.3 3.4 7.6 2.3 5.6 1 1 5 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KFM68030.1 - 0.0095 15.8 22.6 0.087 12.8 0.3 5.9 6 0 0 6 6 6 1 Prokaryotic RING finger family 1 DUF2256 PF10013.9 KFM68030.1 - 0.043 13.9 22.3 4.3 7.5 0.1 6.0 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 KFM68030.1 - 0.11 12.6 27.9 0.14 12.4 12.7 3.5 2 2 0 2 2 2 0 FYVE zinc finger zf-HIT PF04438.16 KFM68030.1 - 0.15 12.0 28.4 12 5.8 0.2 6.1 6 0 0 6 6 6 0 HIT zinc finger zf-RRPl_C4 PF17026.5 KFM68030.1 - 0.19 11.8 20.9 0.21 11.7 6.8 3.1 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Zf_RING PF16744.5 KFM68030.1 - 0.21 11.7 26.6 11 6.2 6.1 5.7 1 1 3 4 4 4 0 KIAA1045 RING finger ADK_lid PF05191.14 KFM68030.1 - 0.25 11.3 21.2 0.57 10.2 1.0 4.2 1 1 3 4 4 4 0 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM68030.1 - 0.31 10.7 26.5 0.58 9.8 0.2 5.6 3 2 3 6 6 6 0 MYST family zinc finger domain zf-HC3 PF16827.5 KFM68030.1 - 0.93 9.7 8.2 67 3.8 0.0 5.0 6 0 0 6 6 6 0 zinc-finger HNH PF01844.23 KFM68030.1 - 1.7 8.8 25.8 6.4 7.0 0.5 5.9 6 0 0 6 6 6 0 HNH endonuclease A2L_zn_ribbon PF08792.10 KFM68030.1 - 2.6 7.9 23.1 9.5 6.1 0.2 6.1 6 0 0 6 6 6 0 A2L zinc ribbon domain zf-Paramyx-P PF13008.7 KFM68030.1 - 2.8 7.5 16.1 32 4.1 0.0 5.4 6 0 0 6 6 6 0 Zinc-binding domain of Paramyxoviridae V protein zf-UDP PF14569.6 KFM68030.1 - 5.3 7.2 16.7 0.27 11.4 3.0 3.3 1 1 2 3 3 3 0 Zinc-binding RING-finger Tnp_P_element PF12017.8 KFM68033.1 - 8e-35 120.2 0.1 8.6e-35 120.1 0.1 1.0 1 0 0 1 1 1 1 Transposase protein DDE_3 PF13358.6 KFM68034.1 - 0.017 14.8 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM68035.1 - 5.1e-56 184.7 60.5 9.2e-10 38.5 2.3 9.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68035.1 - 2.4e-39 131.6 75.6 1.8e-07 31.2 2.0 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68035.1 - 2.6e-29 99.4 68.6 1.2e-05 25.7 1.4 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM68035.1 - 1.4e-19 69.8 57.8 3e-05 24.2 1.0 8.1 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM68035.1 - 2e-15 56.3 54.2 7.6e-05 22.6 0.9 8.8 8 1 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM68035.1 - 6.2e-11 42.3 44.5 0.0034 17.6 0.7 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM68035.1 - 2.3e-08 33.9 28.1 0.012 15.7 0.0 7.6 5 2 2 7 7 7 4 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM68035.1 - 0.00038 20.2 19.4 1.2 9.0 0.3 6.5 1 1 7 8 8 8 2 GAGA factor zf-C2H2_2 PF12756.7 KFM68035.1 - 0.00041 20.6 54.4 0.31 11.4 1.4 7.8 1 1 6 7 7 7 2 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM68035.1 - 0.0031 17.6 35.9 0.074 13.2 7.2 3.3 1 1 2 3 3 3 2 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_9 PF16293.5 KFM68035.1 - 0.0033 17.2 32.4 4.4 7.2 0.1 7.8 2 2 6 8 8 8 2 C2H2 type zinc-finger (1 copy) C1_1 PF00130.22 KFM68035.1 - 0.0063 16.4 41.3 1.2 9.1 4.7 7.0 1 1 5 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 KFM68035.1 - 0.0091 15.9 35.8 0.98 9.4 0.2 7.0 7 0 0 7 7 7 4 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM68035.1 - 0.04 13.5 26.9 0.71 9.5 0.6 7.0 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger BolA PF01722.18 KFM68035.1 - 0.091 13.0 10.2 8.9 6.7 0.7 4.8 1 1 2 4 4 4 0 BolA-like protein Zn-ribbon_8 PF09723.10 KFM68035.1 - 0.33 11.1 26.1 0.21 11.7 2.7 5.6 2 2 5 7 7 7 0 Zinc ribbon domain ADK_lid PF05191.14 KFM68035.1 - 0.76 9.8 32.1 4.6 7.3 3.5 6.2 3 2 5 8 8 8 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM68035.1 - 2.3 9.0 33.0 0.43 11.4 2.7 4.5 1 1 5 6 6 6 0 zinc-ribbon family zf-HIT PF04438.16 KFM68035.1 - 3.5 7.6 43.2 4.3 7.3 0.8 8.1 8 0 0 8 8 8 0 HIT zinc finger Scramblase PF03803.15 KFM68035.1 - 4.7 6.5 7.8 0.85 8.9 1.1 2.2 1 1 1 2 2 2 0 Scramblase PHF5 PF03660.14 KFM68035.1 - 7.6 6.8 26.4 40 4.5 5.0 4.2 1 1 2 3 3 3 0 PHF5-like protein zf-FCS PF06467.14 KFM68035.1 - 9 6.3 33.0 8.1 6.5 0.2 7.2 5 3 3 8 8 8 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.6 KFM68036.1 - 2e-58 192.3 69.3 2.2e-09 37.3 0.5 10.1 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68036.1 - 4.9e-38 127.5 84.3 4.9e-07 29.9 0.3 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68036.1 - 1.7e-31 106.1 79.5 0.00022 21.8 0.4 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM68036.1 - 9.7e-18 63.7 65.0 0.00071 19.5 0.3 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM68036.1 - 3.7e-12 46.2 65.9 0.0027 18.0 6.4 9.4 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM68036.1 - 9.1e-11 41.8 52.8 0.0047 17.2 0.0 9.7 8 2 1 9 9 9 5 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM68036.1 - 9.4e-10 38.6 8.1 0.037 14.3 0.8 5.3 1 1 3 4 4 4 3 BolA-like protein zf-C2H2_11 PF16622.5 KFM68036.1 - 1.2e-05 24.9 40.5 0.022 14.5 0.7 8.3 8 0 0 8 8 8 2 zinc-finger C2H2-type Zf_RING PF16744.5 KFM68036.1 - 0.00023 21.2 36.1 0.032 14.3 0.6 7.8 1 1 7 8 8 8 2 KIAA1045 RING finger GAGA PF09237.11 KFM68036.1 - 0.0038 17.0 15.9 1.7 8.5 0.0 6.4 3 3 5 8 8 8 1 GAGA factor zf-H2C2_5 PF13909.6 KFM68036.1 - 0.0089 15.8 0.1 0.0089 15.8 0.1 9.5 9 2 0 9 9 9 3 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM68036.1 - 0.19 12.1 56.3 0.52 10.7 0.9 7.8 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) Prok-RING_1 PF14446.6 KFM68036.1 - 0.28 11.1 37.1 7.9 6.5 0.1 8.4 7 1 1 8 8 8 0 Prokaryotic RING finger family 1 zf-BED PF02892.15 KFM68036.1 - 0.85 9.7 63.2 0.14 12.2 0.7 8.5 2 2 7 9 9 9 0 BED zinc finger Scramblase PF03803.15 KFM68036.1 - 1.1 8.5 3.9 13 5.0 1.2 2.3 1 1 1 2 2 2 0 Scramblase Zn-ribbon_8 PF09723.10 KFM68036.1 - 3.7 7.8 29.5 0.45 10.7 0.9 5.9 3 2 1 6 6 6 0 Zinc ribbon domain YyzF PF14116.6 KFM68036.1 - 4.4 7.4 32.8 1.4 9.0 0.3 7.9 9 0 0 9 9 9 0 YyzF-like protein FYVE PF01363.21 KFM68036.1 - 4.5 7.5 52.6 0.6 10.3 11.0 6.3 1 1 4 5 5 5 0 FYVE zinc finger TRAF6_Z2 PF18048.1 KFM68036.1 - 4.6 7.4 24.0 4.6 7.4 0.2 6.1 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 Ta0938 PF11494.8 KFM68036.1 - 5.5 7.3 24.1 8.5 6.7 1.6 6.0 1 1 5 6 6 6 0 Ta0938 zf-CHCC PF10276.9 KFM68036.1 - 5.6 7.1 23.5 18 5.5 0.0 6.8 9 0 0 9 9 8 0 Zinc-finger domain DUF2256 PF10013.9 KFM68036.1 - 6.8 6.9 34.1 2.4 8.3 0.1 8.4 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFM68036.1 - 8.3 6.4 36.3 2.4 8.1 0.2 8.7 9 0 0 9 9 9 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFM68037.1 - 2e-79 258.8 81.5 5e-09 36.2 0.9 13.3 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68037.1 - 2.5e-54 178.8 126.0 7.7e-07 29.2 2.7 12.9 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68037.1 - 1.6e-33 112.5 114.6 0.00038 21.0 0.3 12.6 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM68037.1 - 3.2e-24 84.4 87.5 0.00048 20.1 0.1 12.9 12 1 0 12 12 12 9 C2H2-type zinc finger Baculo_IE-1 PF05290.11 KFM68037.1 - 4.6e-07 29.9 41.1 0.039 13.9 4.2 8.1 1 1 4 6 6 6 4 Baculovirus immediate-early protein (IE-0) zinc_ribbon_15 PF17032.5 KFM68037.1 - 8.9e-07 29.6 52.3 0.021 15.5 3.1 6.1 1 1 5 6 6 6 5 zinc-ribbon family zf-met PF12874.7 KFM68037.1 - 2.6e-05 24.5 95.8 0.0098 16.3 3.7 11.9 12 0 0 12 12 12 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM68037.1 - 0.00024 21.3 88.9 0.035 14.4 0.1 11.8 11 1 1 12 12 12 6 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM68037.1 - 0.001 18.8 26.0 0.22 11.4 0.3 7.2 4 2 4 9 9 9 4 GAGA factor Zn-ribbon_8 PF09723.10 KFM68037.1 - 0.0051 16.9 44.4 0.15 12.2 0.9 8.1 3 3 5 9 9 9 4 Zinc ribbon domain Prok-RING_1 PF14446.6 KFM68037.1 - 0.0082 16.1 43.8 5.3 7.0 0.2 11.2 11 1 1 12 12 12 2 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 KFM68037.1 - 0.019 14.5 62.2 2.5 7.7 0.2 11.7 12 0 0 12 12 12 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM68037.1 - 0.029 14.3 60.5 1.2 9.1 1.1 11.5 12 0 0 12 12 12 0 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM68037.1 - 0.2 11.7 0.2 0.2 11.7 0.2 10.4 12 0 0 12 12 12 0 Sec23/Sec24 zinc finger zf_ZIC PF18366.1 KFM68037.1 - 2.6 8.2 78.3 0.5 10.5 3.0 11.7 3 2 9 12 12 12 0 Zic proteins zinc finger domain PAD_M PF08527.10 KFM68037.1 - 5.3 6.7 6.9 17 5.0 0.7 3.4 1 1 2 4 4 4 0 Protein-arginine deiminase (PAD) middle domain IQ PF00612.27 KFM68038.1 - 1.3e-13 49.4 0.2 1.1e-05 24.7 0.1 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Apolipoprotein PF01442.18 KFM68038.1 - 1.5e-10 41.3 114.8 1e-05 25.5 15.7 6.0 1 1 4 5 5 5 4 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KFM68038.1 - 1.9e-05 25.2 104.7 0.0032 18.0 8.1 9.7 2 2 6 9 9 9 7 Bacterial protein of unknown function (DUF883) V-ATPase_G_2 PF16999.5 KFM68038.1 - 0.017 15.6 3.7 0.017 15.6 3.7 8.1 3 1 5 8 8 8 0 Vacuolar (H+)-ATPase G subunit NRD1_2 PF01995.16 KFM68038.1 - 0.11 11.7 9.1 0.13 11.5 0.1 4.0 3 1 1 4 4 4 0 NrpR regulatory domains NRD1 and 2 MRF_C1 PF13887.6 KFM68038.1 - 0.13 11.4 1.8 0.92 8.7 0.1 3.1 3 0 0 3 3 3 0 Myelin gene regulatory factor -C-terminal domain 1 DUF5104 PF17117.5 KFM68038.1 - 6.6 7.2 8.6 1.8 9.0 1.8 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF5104) HTH_Tnp_Tc3_2 PF01498.18 KFM68040.1 - 1.6e-16 60.3 1.6 3.1e-16 59.4 1.6 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68040.1 - 8.8e-05 23.1 7.5 0.00016 22.2 2.6 2.2 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM68040.1 - 0.004 17.0 0.1 1.5 8.8 0.0 2.5 2 0 0 2 2 2 2 MarR family PAX PF00292.18 KFM68040.1 - 0.025 14.5 0.0 0.046 13.6 0.0 1.4 1 1 0 1 1 1 0 'Paired box' domain HTH_24 PF13412.6 KFM68040.1 - 0.08 12.5 0.4 18 5.0 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM68040.1 - 0.22 11.4 1.4 11 6.0 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain Ras PF00071.22 KFM68042.1 - 1.4e-43 148.3 0.5 1.6e-43 148.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM68042.1 - 1e-28 99.9 0.1 1.6e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM68042.1 - 3.4e-14 52.7 0.0 4.1e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM68042.1 - 5.1e-08 32.6 0.0 7.3e-08 32.0 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM68042.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_C93 PF06035.11 KFM68042.1 - 0.017 14.9 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP G-alpha PF00503.20 KFM68042.1 - 0.086 12.0 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 KFM68042.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CLIP_SPH_mas PF18398.1 KFM68043.1 - 8.9e-25 86.8 50.5 4.3e-08 33.4 7.4 4.3 4 0 0 4 4 4 4 Clip-domain serine protease homolog masquerade Trypsin PF00089.26 KFM68043.1 - 0.00093 19.1 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KFM68044.1 - 2.5e-17 63.4 0.1 2.7e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin SAP PF02037.27 KFM68045.1 - 1.3e-12 47.2 0.1 5.7e-12 45.1 0.1 2.2 1 1 1 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 KFM68045.1 - 7.7 6.4 15.9 0.25 11.2 1.3 3.3 3 1 1 4 4 4 0 Tho1/MOS11 C-terminal domain Pkinase PF00069.25 KFM68047.1 - 2.5e-10 40.2 0.1 2.8e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM68047.1 - 0.021 14.1 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Imm7 PF15585.6 KFM68047.1 - 0.059 13.7 0.0 0.072 13.4 0.0 1.2 1 1 0 1 1 1 0 Immunity protein 7 Tetraspanin PF00335.20 KFM68048.1 - 2.1e-18 66.9 11.8 2.8e-18 66.5 11.8 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3493 PF11998.8 KFM68048.1 - 0.001 19.2 5.3 0.079 13.1 0.1 2.6 2 0 0 2 2 2 2 Low psii accumulation1 / Rep27 MARVEL PF01284.23 KFM68048.1 - 0.0063 16.6 7.3 0.01 15.9 7.3 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF2981 PF11200.8 KFM68048.1 - 0.24 11.1 4.4 0.3 10.8 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Ac76 PF05814.11 KFM68048.1 - 0.97 9.5 7.6 0.29 11.2 1.5 2.2 2 0 0 2 2 2 0 Orf76 (Ac76) HTH_Tnp_Tc3_2 PF01498.18 KFM68050.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68050.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68050.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68050.1 - 0.0027 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68050.1 - 2.1 9.0 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68051.1 - 4.2e-16 58.9 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68051.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68051.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68051.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68051.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68052.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68052.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68052.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68052.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68052.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68053.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68053.1 - 9e-14 51.4 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68054.1 - 2.7e-16 59.6 2.2 5e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68054.1 - 1.1e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-Nse PF11789.8 KFM68056.1 - 3.2e-14 52.5 0.7 6.2e-14 51.6 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KFM68056.1 - 5.6e-08 32.8 0.1 1.2e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 U-box domain SesA PF17107.5 KFM68056.1 - 9.7e-05 22.5 0.4 0.00032 20.9 0.2 1.9 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-rbx1 PF12678.7 KFM68056.1 - 0.0048 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFM68056.1 - 0.0073 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM68056.1 - 0.026 14.6 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFM68056.1 - 0.039 14.3 0.1 0.092 13.1 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain LLGL PF08366.13 KFM68057.1 - 3e-38 130.3 0.0 1.3e-37 128.3 0.0 2.1 1 0 0 1 1 1 1 LLGL2 ANAPC4_WD40 PF12894.7 KFM68057.1 - 7.8e-08 32.5 0.0 6.9 7.0 0.0 6.2 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 KFM68057.1 - 5.1e-07 28.7 0.2 1.1e-05 24.4 0.1 2.8 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KFM68057.1 - 1e-06 29.3 4.4 0.12 13.3 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Cas_Cas4 PF01930.17 KFM68057.1 - 0.61 10.2 5.0 1.3 9.1 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF83 DAGK_acc PF00609.19 KFM68058.1 - 4.4e-49 166.9 0.0 5.1e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DUF4407 PF14362.6 KFM68060.1 - 0.0001 21.8 2.0 0.00015 21.2 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) SNARE PF05739.19 KFM68060.1 - 0.00023 21.1 1.9 0.00023 21.1 1.9 2.1 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 KFM68060.1 - 0.0021 17.8 5.5 0.0048 16.7 5.5 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 Herpes_UL17 PF04559.12 KFM68060.1 - 0.088 11.6 0.1 0.094 11.5 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein zf-LITAF-like PF10601.9 KFM68060.1 - 0.17 12.1 0.6 0.31 11.3 0.6 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain SlyX PF04102.12 KFM68060.1 - 3.4 8.3 6.7 0.88 10.2 1.8 2.4 2 2 1 3 3 3 0 SlyX NTR PF01759.21 KFM68061.1 - 9.3e-19 67.2 0.2 1.1e-18 67.0 0.2 1.0 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.24 KFM68062.1 - 1.9e-18 66.3 27.8 1.1e-09 38.2 14.8 2.1 2 0 0 2 2 2 2 Laminin EGF domain EGF_2 PF07974.13 KFM68062.1 - 0.0059 16.9 6.4 0.0059 16.9 6.4 3.8 2 2 1 3 3 3 2 EGF-like domain TPR_10 PF13374.6 KFM68064.1 - 5e-16 58.0 2.4 3.2e-08 33.2 0.2 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM68064.1 - 8.9e-15 54.8 19.3 1.1e-07 32.1 2.6 6.6 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFM68064.1 - 0.0021 18.0 3.4 12 6.3 1.0 5.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM68064.1 - 0.031 14.5 11.6 0.078 13.2 1.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM68064.1 - 0.13 12.1 3.6 1.9 8.4 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_Tnp_Tc3_2 PF01498.18 KFM68065.1 - 4.5e-16 58.8 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68065.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68065.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68065.1 - 0.0026 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68065.1 - 2 9.1 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DUF4371 PF14291.6 KFM68066.1 - 3.9e-09 36.5 0.0 6.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) PepX_C PF08530.10 KFM68066.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain CTP_transf_like PF01467.26 KFM68067.1 - 7.4e-49 165.6 0.1 7.5e-30 104.0 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 KFM68067.1 - 0.007 16.3 0.3 1.6 8.6 0.0 2.8 2 0 0 2 2 2 2 FAD synthetase Pantoate_ligase PF02569.15 KFM68067.1 - 0.021 14.1 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase Oxidored_molyb PF00174.19 KFM68067.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain TMEM173 PF15009.6 KFM68069.1 - 5.4e-19 68.4 0.0 6.2e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 173 DUF1936 PF09151.10 KFM68069.1 - 0.2 11.6 2.3 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) DUF3810 PF12725.7 KFM68070.1 - 2.4 7.4 7.7 15 4.8 7.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3021 PF11457.8 KFM68070.1 - 4.1 7.7 15.4 0.23 11.8 10.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) p450 PF00067.22 KFM68071.1 - 3.1e-09 36.1 0.0 3.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM68072.1 - 1e-63 215.7 0.8 4.3e-63 213.7 0.8 1.8 1 1 0 1 1 1 1 Cytochrome P450 YlaC PF10777.9 KFM68072.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Inner membrane protein YlaC p450 PF00067.22 KFM68073.1 - 1.7e-31 109.5 0.1 2.2e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 KFM68074.1 - 7.3e-12 44.9 0.0 2.4e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GrpE PF01025.19 KFM68075.1 - 3.1e-48 163.6 8.7 4.1e-48 163.2 8.7 1.2 1 0 0 1 1 1 1 GrpE TERB2 PF15101.6 KFM68075.1 - 0.45 10.5 2.7 0.66 10.0 2.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Adhesin_P1_N PF18652.1 KFM68075.1 - 0.68 10.0 8.4 0.58 10.2 6.4 1.9 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain CLZ PF16526.5 KFM68075.1 - 0.86 10.0 8.0 0.31 11.4 4.5 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KASH_CCD PF14662.6 KFM68075.1 - 0.9 9.3 14.4 2.7 7.8 14.3 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Phage_lysis PF03245.13 KFM68075.1 - 3.3 7.9 13.1 0.27 11.4 7.7 2.0 2 1 0 2 2 2 0 Bacteriophage Rz lysis protein CAMSAP_CH PF11971.8 KFM68077.1 - 0.00043 20.1 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain MAF_flag10 PF01973.18 KFM68077.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 Sod_Cu PF00080.20 KFM68077.1 - 0.2 11.8 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.20 KFM68078.1 - 1.6e-31 109.4 0.0 5.4e-10 39.6 0.0 3.2 3 0 0 3 3 3 3 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.20 KFM68079.1 - 5.2e-06 26.7 0.0 0.00029 21.0 0.0 2.6 2 1 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) NatB_MDM20 PF09797.9 KFM68081.1 - 6.1e-88 295.3 3.2 6.1e-88 295.3 3.2 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KFM68081.1 - 1.4e-10 41.5 11.1 0.0031 18.0 0.9 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat NARP1 PF12569.8 KFM68081.1 - 5.9e-10 38.7 7.1 6.9e-08 31.8 0.1 2.8 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 KFM68081.1 - 4e-09 36.5 5.6 0.093 13.6 0.0 6.3 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM68081.1 - 1.4e-06 28.0 6.8 2.6 8.4 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM68081.1 - 5.5e-05 23.7 0.7 1.3 9.7 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM68081.1 - 0.0033 17.4 0.2 52 4.2 0.0 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM68081.1 - 0.0036 16.9 2.3 3.7 7.3 0.0 4.6 5 0 0 5 5 5 1 TPR repeat BTAD PF03704.17 KFM68081.1 - 0.0053 17.2 3.5 0.12 12.8 0.2 3.3 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 KFM68081.1 - 0.023 15.3 7.7 4.3 8.2 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM68081.1 - 0.062 13.5 12.9 1.1 9.5 0.2 4.4 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KFM68081.1 - 0.074 12.9 3.3 12 5.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TRIF-NTD PF17798.1 KFM68081.1 - 0.46 10.6 4.0 0.75 9.9 0.1 3.0 4 0 0 4 4 4 0 TRIF N-terminal domain Fis1_TPR_C PF14853.6 KFM68081.1 - 0.93 9.6 4.7 7.1 6.8 0.3 4.1 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 KFM68081.1 - 1.4 9.4 4.3 3.1 8.4 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM68081.1 - 4.3 7.8 8.7 15 6.1 0.2 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat SKA2 PF16740.5 KFM68082.1 - 6.1e-06 26.0 4.0 7.4e-06 25.7 4.0 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 DUF773 PF05600.12 KFM68082.1 - 0.016 14.0 1.7 0.018 13.8 1.7 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 NUDE_C PF04880.13 KFM68082.1 - 0.025 15.1 0.2 0.031 14.8 0.2 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Muted PF14942.6 KFM68082.1 - 0.095 13.0 3.2 0.12 12.7 3.2 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein SKA1 PF07160.12 KFM68082.1 - 1.6 8.6 6.2 5.4 6.8 0.5 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 SBF PF01758.16 KFM68083.1 - 1.8e-35 122.4 19.3 3.6e-35 121.4 19.3 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family Mem_trans PF03547.18 KFM68083.1 - 0.2 10.0 13.5 0.016 13.7 5.3 2.5 2 1 0 2 2 2 0 Membrane transport protein zf-CCHC_4 PF14392.6 KFM68084.1 - 0.13 12.1 8.6 2.1 8.1 3.6 2.7 2 0 0 2 2 2 0 Zinc knuckle PAS_3 PF08447.12 KFM68086.1 - 8.1e-21 74.1 0.0 7.3e-20 71.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KFM68086.1 - 8.9e-18 64.5 0.5 6.4e-17 61.7 0.1 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFM68086.1 - 0.00013 21.9 0.0 0.089 12.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFM68086.1 - 0.0027 18.0 0.0 0.0041 17.3 0.0 1.3 1 0 0 1 1 1 1 PAS domain SbcCD_C PF13558.6 KFM68088.1 - 3.1e-07 30.5 0.0 6.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KFM68088.1 - 1.6e-06 27.7 11.5 3.4e-06 26.7 11.5 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM68088.1 - 0.0002 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system NPV_P10 PF05531.12 KFM68088.1 - 0.072 13.6 5.3 4.6 7.8 0.6 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC_tran PF00005.27 KFM68088.1 - 0.12 12.9 4.9 2.4 8.7 4.9 2.8 1 1 0 1 1 1 0 ABC transporter DUF2461 PF09365.10 KFM68088.1 - 1.9 8.4 6.4 2.6 8.0 0.0 2.9 3 1 0 3 3 3 0 Conserved hypothetical protein (DUF2461) Muted PF14942.6 KFM68088.1 - 7.9 6.8 26.2 0.5 10.7 7.2 2.7 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Rad50_zn_hook PF04423.14 KFM68089.1 - 5.1e-11 42.2 0.7 5.1e-11 42.2 0.7 7.8 9 0 0 9 9 9 1 Rad50 zinc hook motif PEARLI-4 PF05278.12 KFM68089.1 - 0.0048 16.5 3.6 0.0048 16.5 3.6 6.2 4 2 2 7 7 7 2 Arabidopsis phospholipase-like protein (PEARLI 4) PRKG1_interact PF15898.5 KFM68089.1 - 0.0099 16.8 3.8 0.0099 16.8 3.8 7.4 3 2 3 6 6 6 1 cGMP-dependent protein kinase interacting domain BLOC1_2 PF10046.9 KFM68089.1 - 0.012 15.9 5.6 0.012 15.9 5.6 8.3 3 3 4 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 JIP_LZII PF16471.5 KFM68089.1 - 0.022 14.9 6.2 0.022 14.9 6.2 9.2 8 3 2 10 10 10 0 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 KFM68089.1 - 0.12 12.4 89.8 0.11 12.6 12.9 7.8 5 3 2 7 7 7 0 TPR/MLP1/MLP2-like protein DUF2353 PF09789.9 KFM68089.1 - 1 8.7 73.2 0.041 13.3 18.9 4.1 2 2 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) HrpB7 PF09486.10 KFM68089.1 - 2.3 8.6 39.7 0.66 10.4 3.4 5.2 4 1 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) SpecificRecomb PF10136.9 KFM68089.1 - 6.3 5.0 24.0 0.53 8.5 11.5 2.3 2 0 0 2 2 2 0 Site-specific recombinase DUF4806 PF16064.5 KFM68089.1 - 6.5 7.1 13.5 4.2 7.7 0.3 5.3 4 2 0 4 4 4 0 Domain of unknown function (DUF4806) WEMBL PF05701.11 KFM68089.1 - 6.7 5.3 73.6 2.4 6.8 21.4 3.9 2 2 0 2 2 2 0 Weak chloroplast movement under blue light Spc7 PF08317.11 KFM68089.1 - 7 5.4 95.2 0.21 10.4 12.0 6.2 3 2 3 6 6 6 0 Spc7 kinetochore protein AAA_23 PF13476.6 KFM68090.1 - 7.2e-25 88.7 0.0 8.2e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFM68090.1 - 1.6e-07 31.0 0.0 1.7e-07 30.9 0.0 1.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM68090.1 - 2.9e-07 30.6 0.0 3.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFM68090.1 - 1e-05 25.4 0.0 1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFM68090.1 - 4.5e-05 23.1 0.0 7.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KFM68090.1 - 0.00061 20.3 0.2 0.00087 19.8 0.2 1.4 1 1 0 1 1 1 1 ABC transporter AAA_13 PF13166.6 KFM68090.1 - 0.00078 18.2 0.0 0.0008 18.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM68090.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 KFM68090.1 - 0.04 13.5 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFM68090.1 - 0.051 13.6 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM68090.1 - 0.06 13.6 0.0 0.063 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KFM68090.1 - 0.064 13.5 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 KFM68090.1 - 0.076 13.3 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFM68090.1 - 0.088 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFM68090.1 - 0.15 12.6 0.0 0.18 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUSP PF06337.12 KFM68091.1 - 0.07 13.7 0.0 0.075 13.7 0.0 1.1 1 0 0 1 1 1 0 DUSP domain STAS PF01740.21 KFM68093.1 - 4.2e-08 32.8 0.0 5.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 STAS domain DDE_3 PF13358.6 KFM68094.1 - 5.7e-16 58.6 0.1 3.8e-15 55.9 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68094.1 - 1.6e-10 41.1 1.0 3.1e-10 40.1 1.0 1.5 1 0 0 1 1 1 1 Transposase HLH PF00010.26 KFM68095.1 - 6.9e-08 32.3 0.4 6.9e-08 32.3 0.4 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Mitofilin PF09731.9 KFM68096.1 - 4e-117 392.6 39.0 4.6e-117 392.4 39.0 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein T5orf172 PF10544.9 KFM68096.1 - 0.26 11.8 5.0 1.1 9.9 5.0 2.1 1 0 0 1 1 1 0 T5orf172 domain M_domain PF12938.7 KFM68096.1 - 0.71 9.6 5.3 0.42 10.4 2.7 1.9 2 0 0 2 2 2 0 M domain of GW182 HK97-gp10_like PF04883.12 KFM68096.1 - 1.9 9.5 7.9 1.8 9.6 0.4 3.5 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component Lectin_C PF00059.21 KFM68099.1 - 8.7e-31 106.9 1.3 5.6e-17 62.4 0.0 3.5 3 0 0 3 3 3 3 Lectin C-type domain UL45 PF05473.12 KFM68099.1 - 9.4e-06 25.4 1.6 0.00027 20.6 0.1 3.3 3 2 0 3 3 3 1 UL45 protein, carbohydrate-binding C-type lectin-like Vps55 PF04133.14 KFM68100.1 - 7e-33 113.1 2.8 7.8e-33 112.9 2.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Tmemb_9 PF05434.11 KFM68101.1 - 0.053 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 TMEM9 Ig_3 PF13927.6 KFM68102.1 - 5.9e-11 42.8 0.0 3.6e-06 27.5 0.0 2.9 2 1 1 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM68102.1 - 2.1e-08 34.1 0.0 0.011 15.8 0.0 2.7 2 1 1 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM68102.1 - 1.4e-06 28.5 0.0 8.2e-06 26.1 0.0 2.2 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 KFM68102.1 - 0.0019 18.3 0.1 0.029 14.5 0.1 2.8 3 1 0 3 3 3 1 Immunoglobulin domain Ig_6 PF18452.1 KFM68102.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFM68102.1 - 0.077 13.2 0.2 22 5.3 0.0 3.4 3 2 2 5 5 5 0 Immunoglobulin V-set domain HCV_NS2 PF01538.18 KFM68102.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 TPR_7 PF13176.6 KFM68103.1 - 0.11 12.5 0.5 0.21 11.7 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Voltage_CLC PF00654.20 KFM68104.1 - 1.6e-21 76.9 0.5 1.7e-21 76.9 0.5 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel Voltage_CLC PF00654.20 KFM68105.1 - 3.9e-41 141.5 12.5 4.6e-41 141.2 12.5 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel MAM PF00629.23 KFM68109.1 - 1e-11 45.0 0.3 1.9e-10 40.9 0.1 2.0 1 1 1 2 2 2 2 MAM domain, meprin/A5/mu ANAPC4_WD40 PF12894.7 KFM68111.1 - 0.011 16.0 0.0 7.6 6.9 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM68111.1 - 0.029 13.7 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 WD40-like domain DEAD PF00270.29 KFM68113.1 - 2.8e-23 82.6 0.1 9.2e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM68113.1 - 8e-22 77.7 0.5 4.7e-21 75.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain BTB PF00651.31 KFM68116.1 - 0.0015 18.8 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFM68117.1 - 3.3e-12 46.6 0.1 5.2e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM68117.1 - 5.8e-05 23.1 0.2 0.004 17.2 0.1 2.1 2 0 0 2 2 2 2 BTB And C-terminal Kelch DUF1322 PF07032.11 KFM68117.1 - 0.095 13.2 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) VPS13_mid_rpt PF16910.5 KFM68118.1 - 3.2e-10 39.8 0.0 3.4e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Repeating coiled region of VPS13 Sterol_MT_C PF08498.10 KFM68118.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal VPS13 PF16908.5 KFM68119.1 - 3e-06 27.2 4.8 3e-06 27.2 4.8 1.5 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal FF PF01846.19 KFM68119.1 - 0.11 12.7 1.5 13 6.1 0.1 2.6 2 0 0 2 2 2 0 FF domain Glycos_trans_3N PF02885.17 KFM68120.1 - 5.9e-16 58.1 0.1 7.4e-16 57.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_pol_B_2 PF03175.13 KFM68121.1 - 0.0003 19.8 0.1 0.00032 19.7 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral HTH_Tnp_Tc3_2 PF01498.18 KFM68122.1 - 6.8e-16 58.3 6.5 1.5e-15 57.2 6.5 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68122.1 - 2.4e-15 56.6 0.0 6.2e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM68122.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68122.1 - 0.0042 16.8 0.3 0.12 12.2 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68122.1 - 0.018 15.2 0.1 0.067 13.3 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68122.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.4 3 0 0 3 3 3 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM68123.1 - 2.1e-16 59.9 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68123.1 - 4.2e-13 49.3 0.0 6.8e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease p450 PF00067.22 KFM68124.1 - 3.8e-16 58.9 0.0 4.7e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SASP PF00269.20 KFM68125.1 - 0.0026 17.8 1.3 0.004 17.1 1.3 1.4 1 0 0 1 1 1 1 Small, acid-soluble spore proteins, alpha/beta type Mto2_bdg PF12808.7 KFM68125.1 - 0.027 14.7 2.6 0.039 14.3 2.6 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region YdjM PF04307.14 KFM68126.1 - 7.2e-09 35.2 3.2 9.6e-09 34.8 3.2 1.1 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase HJURP_C PF12347.8 KFM68127.1 - 1.1e-07 31.7 1.8 1.6e-07 31.3 1.8 1.3 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat AKNA PF12443.8 KFM68130.1 - 0.0013 19.4 0.1 0.002 18.7 0.1 1.4 1 0 0 1 1 1 1 AT-hook-containing transcription factor HTH_Tnp_Tc3_2 PF01498.18 KFM68131.1 - 2.6e-16 59.6 2.2 6.4e-16 58.4 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68131.1 - 1.5e-13 50.7 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68131.1 - 1.1e-06 28.3 1.5 2.6e-06 27.1 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68131.1 - 0.003 17.3 0.3 0.011 15.6 0.3 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68131.1 - 3 8.5 14.5 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68132.1 - 4.8e-16 58.8 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68132.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68132.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68132.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68132.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68133.1 - 2.6e-16 59.6 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68133.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68133.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68133.1 - 0.0023 17.7 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68133.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Hist_deacetyl PF00850.19 KFM68134.1 - 1.4e-84 284.2 0.0 1.4e-84 284.2 0.0 3.2 3 0 0 3 3 3 1 Histone deacetylase domain HDAC4_Gln PF12203.8 KFM68134.1 - 1.1e-08 35.1 38.8 1.1e-08 35.1 38.8 3.6 2 2 1 3 3 3 1 Glutamine rich N terminal domain of histone deacetylase 4 TFIIA PF03153.13 KFM68134.1 - 0.0018 18.4 30.7 0.11 12.4 16.3 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy_2 PF13532.6 KFM68135.1 - 2.6e-06 27.8 0.0 1.6e-05 25.2 0.0 2.2 2 1 1 3 3 3 1 2OG-Fe(II) oxygenase superfamily THOC7 PF05615.13 KFM68136.1 - 0.0026 18.0 7.9 0.0036 17.6 7.9 1.3 1 0 0 1 1 1 1 Tho complex subunit 7 Tropomyosin_1 PF12718.7 KFM68136.1 - 0.013 15.7 7.5 0.018 15.2 7.5 1.3 1 0 0 1 1 1 0 Tropomyosin like FliJ PF02050.16 KFM68136.1 - 0.35 11.1 8.0 3.3 8.0 5.4 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein MRPL52 PF18699.1 KFM68136.1 - 0.39 10.9 9.5 0.14 12.3 6.8 1.7 2 0 0 2 2 2 0 Mitoribosomal protein mL52 LMBR1 PF04791.16 KFM68136.1 - 1.2 8.0 7.0 1.4 7.8 7.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FATC PF02260.20 KFM68137.1 - 2.2e-11 43.3 0.3 7.5e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 FATC domain PI3_PI4_kinase PF00454.27 KFM68138.1 - 2.4e-40 138.9 0.0 2.8e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 KFM68139.1 - 1.8e-22 79.5 0.5 1.8e-22 79.5 0.5 2.7 3 0 0 3 3 3 1 Serine/threonine-protein kinase smg-1 PI3_PI4_kinase PF00454.27 KFM68139.1 - 2.1e-09 37.5 0.0 2.1e-09 37.5 0.0 2.4 4 0 0 4 4 4 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KFM68139.1 - 2.6e-06 27.8 6.3 0.00035 20.9 0.3 3.6 2 1 1 3 3 3 2 FKBP12-rapamycin binding domain Pneumovirus_M2 PF06436.11 KFM68139.1 - 0.0059 16.1 0.7 0.02 14.4 0.7 1.9 1 0 0 1 1 1 1 Pneumovirus matrix protein 2 (M2) HEAT PF02985.22 KFM68139.1 - 0.039 14.2 0.0 0.18 12.2 0.0 2.3 1 0 0 1 1 1 0 HEAT repeat mRNA_cap_enzyme PF01331.19 KFM68139.1 - 0.067 13.0 1.0 0.36 10.6 0.1 2.4 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain SMG1 PF15785.5 KFM68140.1 - 6.6e-76 256.0 0.0 7.6e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Serine/threonine-protein kinase smg-1 SMG1 PF15785.5 KFM68141.1 - 4.6e-26 91.4 0.1 4.6e-26 91.4 0.1 2.6 3 0 0 3 3 3 1 Serine/threonine-protein kinase smg-1 VPS53_C PF16854.5 KFM68141.1 - 0.085 12.7 1.8 17 5.2 0.0 3.3 2 1 1 3 3 3 0 Vacuolar protein sorting-associated protein 53 C-terminus TPR_8 PF13181.6 KFM68142.1 - 4e-08 32.8 7.7 3.9e-05 23.5 0.9 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM68142.1 - 4.3e-08 32.7 6.7 0.025 14.7 0.4 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM68142.1 - 5.7e-07 29.7 0.6 0.017 15.4 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM68142.1 - 0.0011 18.8 0.9 8.6 6.7 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM68142.1 - 0.013 14.9 0.0 0.036 13.4 0.0 1.6 1 1 0 1 1 1 0 MalT-like TPR region TPR_10 PF13374.6 KFM68142.1 - 0.068 13.1 0.3 2.5 8.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM68142.1 - 0.19 11.6 8.8 14 5.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Voldacs PF03517.13 KFM68143.1 - 1.2e-26 93.5 3.5 1.2e-26 93.5 3.5 2.0 1 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling PRE_C2HC PF07530.11 KFM68144.1 - 6.5e-11 42.2 0.0 1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Associated with zinc fingers DDE_Tnp_1_7 PF13843.6 KFM68145.1 - 2.1e-82 277.2 0.7 2.5e-82 277.0 0.7 1.1 1 0 0 1 1 1 1 Transposase IS4 Jnk-SapK_ap_N PF09744.9 KFM68146.1 - 0.0082 16.4 0.1 0.012 15.9 0.1 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Syntaxin_2 PF14523.6 KFM68146.1 - 0.048 14.0 0.0 0.14 12.6 0.1 1.8 2 0 0 2 2 2 0 Syntaxin-like protein DDE_3 PF13358.6 KFM68147.1 - 4.7e-16 58.8 0.1 5.8e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68147.1 - 7.7e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68147.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68147.1 - 0.0017 18.1 0.0 0.089 12.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68147.1 - 0.014 15.5 0.1 0.065 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68147.1 - 0.023 14.7 2.1 0.031 14.3 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM68147.1 - 0.081 13.0 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Ion_trans_2 PF07885.16 KFM68148.1 - 1.5e-07 31.3 0.1 1.6e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFM68148.1 - 0.028 13.7 0.1 0.028 13.7 0.1 1.1 1 0 0 1 1 1 0 Ion transport protein C9orf72-like PF15019.6 KFM68150.1 - 1.8e-17 63.7 1.2 2.7e-17 63.1 1.2 1.3 1 0 0 1 1 1 1 C9orf72-like protein family Death PF00531.22 KFM68151.1 - 2.5e-11 43.6 0.0 5.3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Death domain TIR PF01582.20 KFM68151.1 - 4.5e-06 26.6 0.0 7.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFM68151.1 - 5.4e-05 23.8 0.0 0.00017 22.2 0.0 1.8 2 0 0 2 2 2 1 TIR domain ARL2_Bind_BART PF11527.8 KFM68152.1 - 6.9e-36 122.9 1.2 6.9e-36 122.9 1.2 2.2 2 1 0 2 2 2 1 The ARF-like 2 binding protein BART Glyco_transf_54 PF04666.13 KFM68152.1 - 0.034 13.0 0.1 0.061 12.2 0.1 1.3 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF1700 PF08006.11 KFM68152.1 - 0.087 12.4 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) HEPN_RiboL-PSP PF18735.1 KFM68152.1 - 0.097 12.6 0.9 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 RiboL-PSP-HEPN Popeye PF04831.13 KFM68152.1 - 0.17 12.1 0.1 0.29 11.3 0.1 1.3 1 0 0 1 1 1 0 Popeye protein conserved region zf-nanos PF05741.13 KFM68153.1 - 2e-23 82.4 4.8 2e-23 82.4 4.8 2.8 4 0 0 4 4 4 1 Nanos RNA binding domain zf-CCHC_2 PF13696.6 KFM68153.1 - 2 8.3 6.9 0.5 10.3 0.5 2.7 2 0 0 2 2 2 0 Zinc knuckle SMK-1 PF04802.15 KFM68154.1 - 4.7e-78 261.4 7.9 4.7e-78 261.4 7.9 2.2 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.18 KFM68154.1 - 0.0014 18.8 0.0 0.0043 17.3 0.0 1.8 1 0 0 1 1 1 1 RanBP1 domain Rcd1 PF04078.13 KFM68154.1 - 0.0035 16.7 4.5 0.17 11.1 0.5 2.7 3 0 0 3 3 3 2 Cell differentiation family, Rcd1-like WH1 PF00568.23 KFM68154.1 - 0.016 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 WH1 domain Methyltransf_32 PF13679.6 KFM68155.1 - 2.4e-19 69.9 7.4 4.6e-19 69.0 7.4 1.5 1 0 0 1 1 1 1 Methyltransferase domain Prion PF00377.18 KFM68155.1 - 0.0025 17.7 0.1 0.0056 16.5 0.1 1.6 1 0 0 1 1 1 1 Prion/Doppel alpha-helical domain Methyltransf_25 PF13649.6 KFM68155.1 - 0.0026 18.4 0.0 0.0079 16.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFM68155.1 - 0.046 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MFS_1_like PF12832.7 KFM68156.1 - 1.6e-94 316.9 2.2 2.1e-94 316.5 2.2 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM68156.1 - 2e-26 92.8 28.0 2.4e-15 56.3 16.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFM68156.1 - 5.7e-12 45.3 20.7 2.5e-09 36.6 5.8 3.1 3 0 0 3 3 3 3 Nucleoside H+ symporter MFS_2 PF13347.6 KFM68156.1 - 4.2e-06 25.6 15.4 2.3e-05 23.1 0.2 3.3 3 1 0 3 3 3 2 MFS/sugar transport protein LacY_symp PF01306.19 KFM68156.1 - 2.4e-05 23.3 21.9 0.0092 14.8 0.1 3.2 3 0 0 3 3 3 2 LacY proton/sugar symporter MFS_3 PF05977.13 KFM68156.1 - 0.00047 18.7 3.0 0.015 13.7 0.4 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector DDE_3 PF13358.6 KFM68158.1 - 0.00013 21.7 0.1 0.00076 19.3 0.1 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M2 PF01401.18 KFM68159.1 - 8.6e-256 850.0 0.6 2.3e-255 848.6 0.6 1.7 1 0 0 1 1 1 1 Angiotensin-converting enzyme CLASP_N PF12348.8 KFM68160.1 - 8.9e-38 130.1 13.0 1.9e-09 37.4 1.8 6.6 5 2 1 6 6 6 5 CLASP N terminal HEAT PF02985.22 KFM68160.1 - 2.4e-19 67.7 21.0 0.0062 16.7 0.1 13.4 15 0 0 15 15 15 3 HEAT repeat HEAT_2 PF13646.6 KFM68160.1 - 1.6e-15 57.3 0.6 0.18 12.2 0.0 9.6 8 2 2 10 10 9 5 HEAT repeats Cnd1 PF12717.7 KFM68160.1 - 2.2e-10 40.8 27.9 0.004 17.2 0.2 10.2 8 4 3 11 11 11 5 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFM68160.1 - 1.9e-08 34.6 14.7 0.21 12.1 0.1 9.3 10 0 0 10 10 10 2 HEAT-like repeat Tti2 PF10521.9 KFM68160.1 - 2.2e-08 34.0 0.3 0.048 13.2 0.0 4.2 2 1 1 3 3 3 3 Tti2 family Vac14_Fab1_bd PF12755.7 KFM68160.1 - 1.7e-07 31.7 4.5 4.6 7.9 0.0 9.3 8 2 2 10 10 10 1 Vacuolar 14 Fab1-binding region Condensin2nSMC PF12422.8 KFM68160.1 - 0.00024 21.3 5.5 0.022 14.9 0.2 5.0 5 0 0 5 5 5 1 Condensin II non structural maintenance of chromosomes subunit Cohesin_HEAT PF12765.7 KFM68160.1 - 0.0054 17.0 0.1 28 5.1 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Spo0A_C PF08769.11 KFM68160.1 - 0.051 13.7 0.1 0.42 10.7 0.0 2.7 3 0 0 3 3 1 0 Sporulation initiation factor Spo0A C terminal MMS19_N PF14500.6 KFM68160.1 - 0.053 13.1 13.9 3.6 7.1 0.6 7.6 5 2 1 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II Peptidase_M75 PF09375.10 KFM68160.1 - 0.13 11.7 0.8 1.2 8.6 0.0 3.0 4 0 0 4 4 4 0 Imelysin FeoB_Cyto PF17910.1 KFM68160.1 - 0.23 12.1 2.0 1.2 9.7 0.0 3.5 3 0 0 3 3 2 0 FeoB cytosolic helical domain Kinesin PF00225.23 KFM68161.1 - 1.1e-78 264.5 2.0 1.1e-78 264.5 2.0 3.1 3 2 1 4 4 4 1 Kinesin motor domain WD40 PF00400.32 KFM68161.1 - 1.1e-16 60.9 18.3 0.00048 20.9 0.1 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Microtub_bd PF16796.5 KFM68161.1 - 0.00059 19.8 0.0 0.00059 19.8 0.0 2.8 2 1 0 2 2 2 1 Microtubule binding Prefoldin_2 PF01920.20 KFM68161.1 - 0.0019 18.2 8.7 0.0019 18.2 8.7 9.9 9 1 0 10 10 10 2 Prefoldin subunit ANAPC4_WD40 PF12894.7 KFM68161.1 - 0.0096 16.2 3.4 2.3 8.5 0.1 4.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM68161.1 - 0.011 15.1 1.1 0.4 10.0 0.2 2.7 2 0 0 2 2 2 0 WD40-like domain Csm1_N PF18504.1 KFM68161.1 - 0.025 14.9 1.1 0.025 14.9 1.1 10.1 8 1 3 11 11 11 0 Csm1 N-terminal domain DsrC PF04358.13 KFM68161.1 - 0.055 14.0 4.1 0.13 12.8 0.0 3.3 2 0 0 2 2 2 0 DsrC like protein Imm7 PF15585.6 KFM68161.1 - 0.45 10.8 2.9 3.2 8.1 0.1 3.8 3 0 0 3 3 3 0 Immunity protein 7 HTH_Tnp_Tc3_2 PF01498.18 KFM68162.1 - 2.3e-16 59.8 2.2 7e-16 58.2 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68162.1 - 1.7e-13 50.5 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68162.1 - 3.7e-07 29.8 1.6 8.4e-07 28.7 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68162.1 - 0.0028 17.4 0.5 0.0091 15.8 0.5 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68162.1 - 3.7 8.2 15.6 0.15 12.7 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68163.1 - 5.1e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68163.1 - 1.3e-13 50.9 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68163.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68163.1 - 0.0027 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68163.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Anoctamin PF04547.12 KFM68165.1 - 1.1e-25 90.4 0.1 1.2e-25 90.3 0.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoctamin PF04547.12 KFM68166.1 - 1.8e-09 37.0 0.0 2.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ASC PF00858.24 KFM68167.1 - 0.0054 15.8 12.8 0.0056 15.7 12.8 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Ole-e-6 PF09253.10 KFM68167.1 - 0.0072 16.3 5.0 0.0072 16.3 5.0 2.4 1 1 2 3 3 3 1 Pollen allergen ole e 6 Ras PF00071.22 KFM68168.1 - 1.3e-29 102.9 0.0 1.5e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM68168.1 - 4.5e-08 33.3 0.0 7.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PET117 PF15786.5 KFM68168.1 - 0.08 13.2 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Ras PF00071.22 KFM68170.1 - 8.1e-55 184.8 0.0 9.1e-55 184.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM68170.1 - 6.4e-20 71.6 0.0 9.6e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM68170.1 - 7.7e-09 35.2 0.0 9.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM68170.1 - 0.0057 16.2 0.3 0.03 13.9 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PET117 PF15786.5 KFM68170.1 - 0.0091 16.2 0.1 0.015 15.5 0.1 1.3 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Homeodomain PF00046.29 KFM68171.1 - 1.3e-05 24.9 0.3 2.7e-05 23.9 0.3 1.6 1 0 0 1 1 1 1 Homeodomain DUF2721 PF11026.8 KFM68171.1 - 0.027 14.4 0.4 0.038 13.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DDE_3 PF13358.6 KFM68172.1 - 4.3e-09 36.3 0.0 6.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4413 PF14372.6 KFM68172.1 - 0.24 11.8 0.0 0.34 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) HLH PF00010.26 KFM68173.1 - 1.8e-19 69.4 0.5 2.9e-19 68.8 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ARTD15_N PF18084.1 KFM68173.1 - 0.073 13.3 0.0 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 ARTD15 N-terminal domain IKKbetaNEMObind PF12179.8 KFM68173.1 - 0.1 12.6 0.6 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain DUF4363 PF14276.6 KFM68173.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Dicty_REP PF05086.12 KFM68173.1 - 8.2 4.3 7.6 10 4.0 7.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HTH_Tnp_Tc3_2 PF01498.18 KFM68174.1 - 4.5e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68174.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68174.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68174.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68174.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Ig_3 PF13927.6 KFM68176.1 - 2.1e-12 47.5 0.3 2.3e-06 28.1 0.0 2.8 2 1 1 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFM68176.1 - 2.2e-12 47.2 0.7 1.5e-05 25.3 0.0 3.2 2 2 1 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFM68176.1 - 1.2e-07 31.9 0.4 1.2e-06 28.6 0.0 2.4 2 1 1 3 3 3 1 Immunoglobulin V-set domain ig PF00047.25 KFM68176.1 - 7e-07 29.3 0.1 0.00076 19.6 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM68176.1 - 1.4e-06 28.3 0.0 0.0028 17.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFM68176.1 - 1.4e-05 25.0 0.3 5e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM68176.1 - 0.0054 17.0 0.1 9.9 6.5 0.0 3.5 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 KFM68176.1 - 0.15 12.3 0.1 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin C2-set domain CN_hydrolase PF00795.22 KFM68177.1 - 4.5e-34 118.0 0.0 6.3e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KFM68177.1 - 2.3e-09 36.7 0.0 7.3e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 NAD synthase Rota_NSP3 PF01665.16 KFM68177.1 - 0.047 12.8 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 DDE_3 PF13358.6 KFM68178.1 - 2.7e-13 49.9 0.0 3.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-SCNM1 PF15803.5 KFM68178.1 - 0.065 12.9 0.2 0.73 9.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 RVT_1 PF00078.27 KFM68180.1 - 8.1e-05 22.2 0.0 0.0055 16.3 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) CYTL1 PF15153.6 KFM68180.1 - 0.044 13.7 0.5 0.062 13.2 0.5 1.3 1 0 0 1 1 1 0 Cytokine-like protein 1 Ig_3 PF13927.6 KFM68181.1 - 2.8e-18 66.3 0.4 2.8e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM68181.1 - 3.4e-14 52.7 0.0 1.6e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM68181.1 - 2.6e-12 46.7 0.0 3.4e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM68181.1 - 5.9e-12 45.8 0.1 2.6e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM68181.1 - 1.8e-06 28.1 0.2 0.0098 16.1 0.0 3.1 2 1 1 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM68181.1 - 0.00039 20.4 1.0 0.0025 17.8 0.0 2.5 2 1 1 3 3 3 1 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFM68181.1 - 0.095 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 DDE_Tnp_1_7 PF13843.6 KFM68182.1 - 1.7e-27 96.7 0.1 1.9e-27 96.5 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 Ig_5 PF16681.5 KFM68183.1 - 7.3e-06 26.3 0.0 0.00037 20.9 0.0 2.0 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_3 PF13927.6 KFM68183.1 - 9.2e-06 26.2 0.0 1.5e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM68183.1 - 4.6e-05 23.7 0.0 8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM68183.1 - 0.00046 20.2 0.2 0.0023 18.0 0.2 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_4 PF16680.5 KFM68183.1 - 0.0016 18.6 0.0 0.0094 16.2 0.0 1.9 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 KFM68183.1 - 0.11 12.7 0.1 0.99 9.6 0.1 2.0 1 1 1 2 2 2 0 Immunoglobulin V-set domain SPG48 PF14764.6 KFM68184.1 - 2.8e-26 92.3 7.8 2.7e-25 89.1 1.2 3.3 3 1 0 3 3 3 2 AP-5 complex subunit, vesicle trafficking Ribosomal_60s PF00428.19 KFM68185.1 - 0.14 12.8 0.0 0.17 12.5 0.0 1.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein eRF1_2 PF03464.15 KFM68186.1 - 1.3e-48 164.6 0.0 2e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFM68186.1 - 3.3e-38 130.7 0.1 6.7e-38 129.6 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KFM68186.1 - 3.2e-20 72.4 0.0 9.8e-20 70.9 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 1 acVLRF1 PF18859.1 KFM68186.1 - 1.2e-10 41.8 0.0 1.8e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KFM68186.1 - 3.1e-09 37.2 0.0 5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Pro_isomerase PF00160.21 KFM68189.1 - 4.3e-49 166.8 0.1 1.2e-48 165.3 0.1 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD His_Phos_2 PF00328.22 KFM68191.1 - 6.5e-102 341.7 0.6 9.1e-102 341.3 0.6 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KFM68191.1 - 9e-43 144.4 0.3 2.2e-42 143.1 0.3 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KFM68191.1 - 0.00083 19.0 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain HTH_Tnp_Tc3_2 PF01498.18 KFM68193.1 - 2.6e-16 59.6 2.2 4.8e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68193.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68194.1 - 2e-16 60.0 2.2 4.3e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68194.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M13 PF01431.21 KFM68195.1 - 8e-20 71.3 0.8 3.1e-09 36.8 0.1 2.0 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM68196.1 - 2.7e-46 159.0 6.6 3.5e-46 158.6 6.6 1.1 1 0 0 1 1 1 1 Peptidase family M13 DUF5341 PF17276.2 KFM68196.1 - 0.92 9.7 5.7 3 8.0 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5341) zf-C2H2_jaz PF12171.8 KFM68197.1 - 5.5e-12 45.7 16.8 1.6e-10 41.0 3.8 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM68197.1 - 1.9e-09 37.6 11.0 1.7e-06 28.2 1.9 2.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFM68197.1 - 3e-09 37.1 5.9 0.00068 19.9 0.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM68197.1 - 3.7e-05 24.2 3.6 0.12 13.3 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM68197.1 - 0.0028 18.0 6.7 0.1 13.1 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF2256 PF10013.9 KFM68197.1 - 0.028 14.5 1.4 1.1 9.5 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM68197.1 - 0.11 12.6 11.1 0.23 11.6 0.4 3.0 4 0 0 4 4 4 0 DBF zinc finger zinc_ribbon_5 PF13719.6 KFM68197.1 - 0.14 12.0 0.8 0.78 9.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 KFM68197.1 - 0.89 9.6 7.9 0.85 9.7 1.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger 3HCDH_N PF02737.18 KFM68197.1 - 4.3 7.2 11.3 0.72 9.7 7.0 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-RVT PF13966.6 KFM68199.1 - 0.0058 17.3 0.1 0.0078 16.9 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.18 KFM68200.1 - 2.1e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68200.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68201.1 - 2.2e-16 59.9 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68201.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68202.1 - 5.1e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68202.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68202.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68202.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68202.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68203.1 - 5.1e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68203.1 - 2e-13 50.3 0.0 3.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68203.1 - 3.2e-07 30.0 2.1 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68203.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68203.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68204.1 - 4.8e-16 58.8 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68204.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68204.1 - 2e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68204.1 - 0.0025 17.6 0.6 0.0078 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68204.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68205.1 - 4.6e-16 58.8 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68205.1 - 1.2e-13 51.0 0.0 2.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68205.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68205.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68205.1 - 2.3 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DUF4371 PF14291.6 KFM68206.1 - 3.5e-05 23.6 0.0 7.5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) MCM_lid PF17855.1 KFM68206.1 - 0.042 14.3 2.3 0.092 13.2 1.2 2.1 1 1 1 2 2 2 0 MCM AAA-lid domain HTH_Tnp_Tc3_2 PF01498.18 KFM68207.1 - 4.9e-16 58.7 3.5 6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68207.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68207.1 - 2.2e-07 30.5 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68207.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68207.1 - 2 9.1 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain zf-C4H2 PF10146.9 KFM68209.1 - 4.4e-40 138.3 15.0 4.9e-40 138.1 15.0 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein KASH_CCD PF14662.6 KFM68209.1 - 0.0044 16.9 12.9 0.0053 16.6 12.9 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH ETC_C1_NDUFA5 PF04716.14 KFM68209.1 - 0.02 14.7 0.7 0.057 13.2 0.7 1.7 1 0 0 1 1 1 0 ETC complex I subunit conserved region XhlA PF10779.9 KFM68209.1 - 0.056 13.7 3.0 0.056 13.7 3.0 2.0 2 0 0 2 2 2 0 Haemolysin XhlA WAPL PF07814.13 KFM68209.1 - 0.1 11.3 3.9 0.12 11.1 3.9 1.1 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Spc7 PF08317.11 KFM68209.1 - 0.16 10.8 9.5 0.21 10.4 9.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4164 PF13747.6 KFM68209.1 - 0.65 10.3 7.5 0.37 11.1 2.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ERM PF00769.19 KFM68209.1 - 0.91 9.3 16.1 2.6 7.8 16.1 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family bZIP_2 PF07716.15 KFM68209.1 - 1.4 9.1 9.9 1.5 8.9 0.3 3.1 3 0 0 3 3 3 0 Basic region leucine zipper TGT PF01702.18 KFM68210.1 - 2.2e-66 224.4 0.0 2.7e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thiolase_N PF00108.23 KFM68212.1 - 4.4e-91 304.8 1.1 5.1e-91 304.6 1.1 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 KFM68212.1 - 3.6e-05 23.5 4.4 4e-05 23.3 2.0 2.1 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain RRM_1 PF00076.22 KFM68213.1 - 5.1e-21 74.3 0.0 8.3e-21 73.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM68213.1 - 0.00034 20.5 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFM68213.1 - 0.0023 17.5 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM68213.1 - 0.031 14.1 0.0 0.053 13.4 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KFM68213.1 - 0.058 13.6 0.0 2.3 8.4 0.0 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter SET_assoc PF11767.8 KFM68213.1 - 0.079 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Myb_DNA-binding PF00249.31 KFM68214.1 - 5.7e-08 32.8 0.4 1.3e-07 31.7 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KFM68214.1 - 1.2e-06 28.2 10.3 2.3e-06 27.3 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 KFM68214.1 - 0.00057 20.1 0.1 0.0015 18.8 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain NDC10_II PF16787.5 KFM68214.1 - 0.022 13.8 0.2 0.035 13.2 0.2 1.3 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 eIF3g PF12353.8 KFM68214.1 - 0.16 12.3 3.6 11 6.5 0.6 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G OST3_OST6 PF04756.13 KFM68215.1 - 5.6e-08 32.5 0.6 6.8e-08 32.2 0.6 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DmsC PF04976.12 KFM68215.1 - 0.0051 16.3 0.1 0.0088 15.6 0.1 1.3 1 0 0 1 1 1 1 DMSO reductase anchor subunit (DmsC) Death PF00531.22 KFM68221.1 - 0.02 15.1 0.0 0.067 13.4 0.0 1.9 2 0 0 2 2 2 0 Death domain DUF1045 PF06299.12 KFM68221.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) Glypican PF01153.19 KFM68222.1 - 1.7e-120 403.5 0.0 2.1e-120 403.2 0.0 1.0 1 0 0 1 1 1 1 Glypican Fz PF01392.22 KFM68222.1 - 0.01 16.4 0.5 0.022 15.4 0.5 1.5 1 0 0 1 1 1 0 Fz domain MINDY_DUB PF04424.13 KFM68224.1 - 0.0043 17.1 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase TSSC4 PF15264.6 KFM68224.1 - 0.033 14.4 0.2 0.043 14.1 0.2 1.1 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 P4Ha_N PF08336.11 KFM68225.1 - 0.058 13.4 0.1 0.068 13.2 0.1 1.1 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region P4Ha_N PF08336.11 KFM68226.1 - 9.4e-11 41.9 0.0 1e-10 41.7 0.0 1.0 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFM68228.1 - 0.0001 23.1 3.2 0.0062 17.4 0.1 2.6 2 1 1 3 3 3 2 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KFM68229.1 - 5.3e-49 167.0 13.7 6.2e-49 166.8 13.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM68229.1 - 4.4e-10 39.0 5.4 4.4e-10 39.0 5.4 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter NHL PF01436.21 KFM68231.1 - 2.2e-18 65.3 0.7 0.00089 19.2 0.0 5.1 4 0 0 4 4 4 4 NHL repeat Filamin PF00630.19 KFM68231.1 - 3.1e-12 47.2 0.3 8.6e-12 45.8 0.3 1.9 1 1 0 1 1 1 1 Filamin/ABP280 repeat DUF5128 PF17170.4 KFM68231.1 - 0.0073 15.5 1.4 5.9 5.9 0.0 3.6 1 1 2 3 3 3 1 6-bladed beta-propeller DUF3583 PF12126.8 KFM68231.1 - 0.011 15.2 2.8 0.017 14.6 2.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3583) AAA_13 PF13166.6 KFM68231.1 - 0.025 13.2 8.9 0.035 12.8 8.9 1.1 1 0 0 1 1 1 0 AAA domain ApoLp-III PF07464.11 KFM68231.1 - 0.033 14.3 8.0 0.068 13.3 8.0 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Invasin_D3 PF09134.10 KFM68231.1 - 0.067 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Invasin, domain 3 DUF3584 PF12128.8 KFM68231.1 - 0.075 10.6 7.1 0.1 10.1 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 KFM68231.1 - 0.11 12.9 5.7 0.55 10.7 0.3 2.4 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4795 PF16043.5 KFM68231.1 - 0.12 12.0 8.9 0.18 11.4 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) YkyA PF10368.9 KFM68231.1 - 0.2 11.3 11.8 0.34 10.6 11.8 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein EspB PF05802.11 KFM68231.1 - 0.26 11.2 2.4 0.42 10.6 2.4 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF948 PF06103.11 KFM68231.1 - 0.28 11.5 5.3 2.6 8.3 1.5 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 KFM68231.1 - 0.58 9.7 5.7 0.86 9.1 5.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tweety PF04906.13 KFM68231.1 - 0.61 8.7 4.2 1.4 7.6 4.1 1.5 1 1 1 2 2 2 0 Tweety Spc7 PF08317.11 KFM68231.1 - 0.71 8.7 10.3 1.1 8.0 10.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFM68231.1 - 0.95 9.5 14.7 2.8 7.9 14.7 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3251 PF11622.8 KFM68231.1 - 1.6 8.3 5.3 12 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3251) DUF1664 PF07889.12 KFM68231.1 - 2 8.5 8.2 6.5 6.8 7.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KFM68231.1 - 4.1 7.9 10.2 7.6 7.1 10.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Spectrin PF00435.21 KFM68231.1 - 4.8 7.7 6.5 20 5.8 0.5 2.3 1 1 1 2 2 2 0 Spectrin repeat CorA PF01544.18 KFM68231.1 - 5.6 6.2 6.0 5.1 6.3 0.7 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KFM68231.1 - 7.5 6.6 9.9 29 4.7 4.7 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-MYND PF01753.18 KFM68233.1 - 1.4e-09 37.9 14.1 2.4e-09 37.1 14.1 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KFM68233.1 - 1.3 9.4 12.2 23 5.4 12.2 2.2 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding AhpC-TSA PF00578.21 KFM68234.1 - 3.6e-31 107.7 0.0 4.6e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM68234.1 - 3.3e-16 59.3 0.0 4.6e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFM68234.1 - 3e-07 30.2 0.0 5.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 KFM68234.1 - 2.4e-06 27.6 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DEAD PF00270.29 KFM68235.1 - 5.9e-44 149.9 0.1 1e-43 149.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM68235.1 - 2e-33 115.0 0.1 3.1e-32 111.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KFM68235.1 - 9.9e-05 22.7 0.0 0.0011 19.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain UTP25 PF06862.12 KFM68235.1 - 0.0001 21.2 0.0 0.3 9.8 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_30 PF13604.6 KFM68235.1 - 0.00023 20.9 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFM68235.1 - 0.0036 17.3 0.0 0.0068 16.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KFM68235.1 - 0.038 13.5 0.2 0.075 12.5 0.1 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KFM68235.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KFM68235.1 - 0.26 11.5 0.9 1.6 9.0 0.9 2.1 1 1 0 1 1 1 0 AAA domain Lig_chan-Glu_bd PF10613.9 KFM68237.1 - 2.9e-19 69.4 0.0 3.5e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site HTH_Tnp_Tc3_2 PF01498.18 KFM68238.1 - 3.9e-16 59.1 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68238.1 - 1.5e-13 50.7 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68238.1 - 3.3e-07 30.0 1.6 7.7e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68238.1 - 0.0029 17.4 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68238.1 - 2.8 8.6 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain ANF_receptor PF01094.28 KFM68239.1 - 3.4e-05 23.1 0.0 3.8e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region HTH_28 PF13518.6 KFM68241.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM68241.1 - 2.6e-05 24.2 0.6 0.0014 18.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM68241.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.5 1 1 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 KFM68241.1 - 0.032 14.1 0.0 0.045 13.7 0.0 1.3 1 1 0 1 1 1 0 MarR family CENP-B_N PF04218.13 KFM68241.1 - 0.035 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Pterin_4a PF01329.19 KFM68242.1 - 1.1e-31 108.9 0.0 1.3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Kri1_C PF12936.7 KFM68243.1 - 1.3e-32 111.8 2.7 1.3e-32 111.8 2.7 6.2 7 0 0 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.12 KFM68243.1 - 4.1e-21 75.5 19.0 4.1e-21 75.5 19.0 7.9 4 3 1 6 6 6 1 KRI1-like family Ammonium_transp PF00909.21 KFM68244.1 - 1.1e-15 57.3 0.1 1.5e-15 56.8 0.1 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family FtsX PF02687.21 KFM68244.1 - 0.048 14.1 6.0 0.21 12.1 6.0 1.9 1 1 0 1 1 1 0 FtsX-like permease family Ammonium_transp PF00909.21 KFM68245.1 - 1.7e-09 36.9 1.7 1.7e-09 36.9 1.7 1.3 2 0 0 2 2 2 1 Ammonium Transporter Family Ammonium_transp PF00909.21 KFM68246.1 - 6.2e-26 91.0 8.2 7e-26 90.8 8.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 KFM68247.1 - 5.3e-33 114.3 8.0 8.6e-33 113.6 8.0 1.3 1 1 0 1 1 1 1 Ammonium Transporter Family APP_N PF02177.16 KFM68249.1 - 2.1e-11 44.0 0.1 2.8e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding ANF_receptor PF01094.28 KFM68251.1 - 4.3e-20 72.1 0.0 5.2e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region KAP PF05804.12 KFM68251.1 - 0.09 10.9 0.1 0.11 10.7 0.1 1.0 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) 7tm_3 PF00003.22 KFM68252.1 - 3.2e-54 184.2 11.0 3.6e-54 184.0 11.0 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF1418 PF07214.12 KFM68252.1 - 0.088 12.7 3.1 3.6 7.5 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1418) ABC2_membrane_2 PF12679.7 KFM68252.1 - 8.7 5.5 11.8 0.48 9.7 6.0 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein Cast PF10174.9 KFM68253.1 - 1.8 6.7 6.8 0.27 9.4 1.4 1.8 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone HTH_Tnp_Tc3_2 PF01498.18 KFM68254.1 - 6.3e-11 42.4 4.6 1.2e-10 41.5 4.6 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68254.1 - 3.4e-07 30.1 0.0 8.3e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Ploopntkinase1 PF18748.1 KFM68254.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 HTH_33 PF13592.6 KFM68254.1 - 0.064 12.9 0.2 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Winged helix-turn helix MgtE PF01769.16 KFM68255.1 - 1.8e-50 170.5 23.6 4.5e-28 98.1 2.2 3.2 2 1 1 3 3 3 2 Divalent cation transporter HTH_38 PF13936.6 KFM68256.1 - 0.00041 20.1 0.0 0.0007 19.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DDE_3 PF13358.6 KFM68256.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Bac_DnaA_C PF08299.11 KFM68256.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix PRANC PF09372.10 KFM68256.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 PRANC domain HTH_Tnp_Tc3_2 PF01498.18 KFM68257.1 - 7.2e-16 58.2 6.5 1.5e-15 57.2 6.5 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68257.1 - 1.4e-15 57.3 0.1 5.8e-15 55.3 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM68257.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.9 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68257.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68257.1 - 0.01 15.9 0.1 0.066 13.4 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68257.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix MgtE PF01769.16 KFM68259.1 - 1.6e-48 164.2 24.9 1.9e-26 92.8 2.5 3.1 3 0 0 3 3 3 2 Divalent cation transporter FbpA PF05833.11 KFM68260.1 - 1.8e-39 135.8 13.7 1.8e-39 135.8 13.7 2.1 3 0 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KFM68260.1 - 1.1e-34 119.3 0.9 2.7e-34 118.1 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 KFM68260.1 - 7.5e-30 103.0 0.0 7.5e-30 103.0 0.0 3.5 4 0 0 4 4 4 1 NFACT protein C-terminal domain HTH_IclR PF09339.10 KFM68261.1 - 2.8e-05 23.8 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_32 PF13565.6 KFM68261.1 - 0.0034 18.0 0.8 0.005 17.4 0.2 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68261.1 - 0.0065 16.2 0.6 0.01 15.6 0.6 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_AraC PF00165.23 KFM68261.1 - 0.033 14.3 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Nrap_D2 PF17403.2 KFM68261.1 - 0.088 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain RhoGAP PF00620.27 KFM68262.1 - 9.9e-48 161.8 1.3 4.4e-47 159.7 0.2 2.3 2 0 0 2 2 2 1 RhoGAP domain BAR_3 PF16746.5 KFM68262.1 - 1.9e-25 90.0 4.7 4.1e-25 88.9 4.7 1.6 1 0 0 1 1 1 1 BAR domain of APPL family SH3_9 PF14604.6 KFM68262.1 - 4.7e-11 42.4 0.1 9.2e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM68262.1 - 8.4e-08 31.8 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM68262.1 - 1.4e-07 31.0 0.0 2.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFM68262.1 - 2.1e-06 28.2 0.5 7e-06 26.5 0.1 2.2 2 0 0 2 2 2 1 PH domain DUF4924 PF16271.5 KFM68262.1 - 0.056 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) Nod1 PF17114.5 KFM68262.1 - 0.15 12.2 0.6 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 HTH_Tnp_Tc3_2 PF01498.18 KFM68263.1 - 2e-09 37.6 3.4 3.8e-09 36.7 3.4 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68263.1 - 0.00071 20.1 0.6 0.00071 20.1 0.6 2.1 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.6 KFM68263.1 - 0.0061 16.3 0.0 0.06 13.1 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68263.1 - 0.0067 16.2 3.5 0.055 13.2 0.1 3.4 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68263.1 - 0.76 9.7 0.1 0.76 9.7 0.1 3.2 5 0 0 5 5 5 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68264.1 - 4.3e-16 58.9 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68264.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68264.1 - 1.6e-07 31.0 1.2 6.8e-07 28.9 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68264.1 - 0.0023 17.7 1.2 0.0073 16.1 0.6 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68264.1 - 0.027 14.6 0.4 0.088 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM68264.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_1 PF03184.19 KFM68266.1 - 4.7e-39 133.8 0.6 9e-39 132.9 0.6 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM68266.1 - 2.2e-19 69.2 0.1 5.1e-19 68.1 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM68266.1 - 3.7e-08 32.9 0.6 7.3e-08 31.9 0.6 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_24 PF13412.6 KFM68266.1 - 0.00059 19.3 0.2 0.0014 18.2 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF2205 PF10224.9 KFM68266.1 - 0.11 12.5 2.6 0.4 10.7 0.3 2.3 2 0 0 2 2 2 0 Short coiled-coil protein HTH_Tnp_Tc3_2 PF01498.18 KFM68267.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68267.1 - 8.4e-14 51.5 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68268.1 - 1.2e-07 31.8 0.6 1.7e-07 31.4 0.6 1.2 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68268.1 - 0.0016 19.0 1.5 0.002 18.7 1.5 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_12 PF08461.10 KFM68268.1 - 0.029 14.3 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain NOA36 PF06524.12 KFM68269.1 - 7.7e-161 534.5 46.8 8.6e-161 534.3 46.8 1.0 1 0 0 1 1 1 1 NOA36 protein PPP4R2 PF09184.11 KFM68269.1 - 3.1 7.3 10.7 4.1 6.9 10.7 1.2 1 0 0 1 1 1 0 PPP4R2 Methyltransf_11 PF08241.12 KFM68271.1 - 2.6e-08 34.4 0.0 3.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM68271.1 - 9.2e-08 32.1 0.0 1e-07 31.9 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM68271.1 - 0.00021 21.9 0.0 0.00027 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM68271.1 - 0.00074 19.3 0.0 0.00084 19.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM68271.1 - 0.00088 20.0 0.0 0.0012 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_7 PF03492.15 KFM68271.1 - 0.017 14.4 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Ubie_methyltran PF01209.18 KFM68271.1 - 0.066 12.5 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Nop53 PF07767.11 KFM68273.1 - 1.3e-81 275.0 33.8 1.5e-81 274.9 33.8 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) MEA1 PF06910.11 KFM68274.1 - 7.1e-17 62.2 2.3 2.1e-16 60.7 2.3 1.8 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) I-set PF07679.16 KFM68275.1 - 7.8e-10 38.7 0.0 9.1e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM68275.1 - 2.9e-09 37.4 0.0 4.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM68275.1 - 1.3e-08 34.8 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM68275.1 - 6.8e-07 29.5 0.0 8.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Receptor_2B4 PF11465.8 KFM68275.1 - 0.0047 17.1 0.0 0.0058 16.8 0.0 1.1 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFM68275.1 - 0.043 13.9 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain V-set PF07686.17 KFM68275.1 - 0.057 13.6 0.0 2.7 8.2 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM68275.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Sec1 PF00995.23 KFM68276.1 - 0.0093 15.2 0.7 0.013 14.8 0.7 1.1 1 0 0 1 1 1 1 Sec1 family DDE_3 PF13358.6 KFM68277.1 - 5.2e-07 29.5 0.0 6.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease START PF01852.19 KFM68279.1 - 4.3e-20 72.0 0.4 7.3e-20 71.3 0.4 1.2 1 0 0 1 1 1 1 START domain 2OG-FeII_Oxy_3 PF13640.6 KFM68279.1 - 0.063 14.2 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SFTA2 PF15210.6 KFM68283.1 - 0.066 13.2 0.2 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 Surfactant-associated protein 2 SMI1_KNR4 PF09346.10 KFM68283.1 - 0.1 13.0 0.0 0.85 10.0 0.0 2.3 2 1 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KFM68283.1 - 0.1 13.0 0.0 20 5.6 0.0 2.8 2 1 0 2 2 2 0 SMI1-KNR4 cell-wall PQQ PF01011.21 KFM68283.1 - 0.13 12.2 0.0 23 5.2 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat PTPLA PF04387.14 KFM68284.1 - 5.7e-55 185.5 3.3 8.2e-55 185.0 3.3 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA C2 PF00168.30 KFM68286.1 - 1.4e-28 99.2 0.0 8.8e-13 48.4 0.0 2.7 3 0 0 3 3 3 2 C2 domain HTH_Tnp_Tc3_2 PF01498.18 KFM68287.1 - 1.2e-06 28.7 0.1 2.2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Transposase DUF4817 PF16087.5 KFM68287.1 - 1.4e-06 28.0 0.6 3.7e-06 26.6 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) CENP-B_N PF04218.13 KFM68287.1 - 0.0017 18.0 0.1 0.0033 17.0 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_6 PF01418.17 KFM68287.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family HTH_IclR PF09339.10 KFM68287.1 - 0.0039 16.9 0.3 0.0065 16.3 0.3 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_32 PF13565.6 KFM68287.1 - 0.0054 17.3 0.3 0.015 15.9 0.3 1.8 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 KFM68287.1 - 0.01 15.7 0.2 0.018 14.9 0.2 1.4 1 0 0 1 1 1 0 MarR family HTH_Tnp_ISL3 PF13542.6 KFM68287.1 - 0.031 13.7 0.3 0.066 12.6 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MarR PF01047.22 KFM68287.1 - 0.078 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 KFM68287.1 - 0.091 12.7 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 HTH domain DUF134 PF02001.16 KFM68287.1 - 0.15 12.6 0.0 0.26 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF134 DDE_3 PF13358.6 KFM68288.1 - 2.5e-11 43.6 0.0 4.4e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease AAA PF00004.29 KFM68290.1 - 2.7e-09 37.5 0.1 6.5e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 KFM68290.1 - 9.8e-08 32.0 0.1 3.1e-07 30.3 0.1 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 KFM68290.1 - 0.00039 20.2 0.0 0.0041 16.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KFM68290.1 - 0.0047 16.3 0.4 0.013 14.9 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KFM68290.1 - 0.0082 16.4 0.3 0.18 12.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFM68290.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KFM68290.1 - 0.022 14.5 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KFM68290.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KFM68290.1 - 0.11 11.9 0.0 0.57 9.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein PP2C PF00481.21 KFM68291.1 - 0.0088 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KFM68292.1 - 2.8e-21 76.3 0.0 3e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KFM68293.1 - 2.7e-18 66.5 0.0 2.9e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C TSP_1 PF00090.19 KFM68295.1 - 9.1e-35 118.6 69.1 1.5e-13 50.7 7.4 6.2 5 1 0 5 5 5 4 Thrombospondin type 1 domain Sema PF01403.19 KFM68295.1 - 1.4e-18 67.0 0.7 6e-18 64.9 0.1 2.1 1 1 1 2 2 2 1 Sema domain PSI PF01437.25 KFM68295.1 - 5.5e-07 30.0 3.7 5.5e-07 30.0 3.7 3.2 2 1 0 2 2 2 1 Plexin repeat PAP2 PF01569.21 KFM68295.1 - 0.55 10.0 1.9 0.76 9.6 0.7 1.8 2 0 0 2 2 2 0 PAP2 superfamily Ig_3 PF13927.6 KFM68296.1 - 1.5e-41 140.9 2.0 1.3e-13 51.3 0.0 4.8 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFM68296.1 - 4.3e-41 138.9 0.0 8.8e-12 44.9 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM68296.1 - 1.8e-30 105.1 3.5 1.3e-10 41.4 0.0 4.8 5 0 0 5 5 5 3 Immunoglobulin domain ig PF00047.25 KFM68296.1 - 2.9e-15 56.2 3.4 8.7e-06 25.8 0.0 5.5 5 2 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 KFM68296.1 - 2.5e-13 50.1 10.1 0.056 13.6 0.3 7.7 5 3 0 5 5 5 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM68296.1 - 2.7e-08 33.2 0.0 0.038 13.6 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFM68296.1 - 5.7e-07 29.5 0.3 2.1 8.5 0.0 3.8 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain C2-set PF05790.15 KFM68296.1 - 0.12 12.5 0.0 37 4.6 0.0 3.4 4 0 0 4 4 4 0 Immunoglobulin C2-set domain fn3 PF00041.21 KFM68297.1 - 8.8e-15 54.8 0.2 1.1e-14 54.5 0.2 1.0 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM68297.1 - 0.022 15.3 0.2 0.035 14.7 0.2 1.3 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFM68297.1 - 0.072 13.2 0.0 0.077 13.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin type III domain DUF4371 PF14291.6 KFM68298.1 - 1.3e-30 106.8 0.5 2.6e-30 105.8 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM68298.1 - 1.7e-09 37.3 0.0 4.3e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PAP_central PF04928.17 KFM68298.1 - 2.8 6.9 5.5 1.9 7.4 0.7 2.4 2 0 0 2 2 2 0 Poly(A) polymerase central domain Exonuc_VII_L PF02601.15 KFM68298.1 - 4.3 6.8 9.7 3.9 6.9 2.7 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit TDP43_N PF18694.1 KFM68299.1 - 3e-34 116.7 0.0 5.4e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 KFM68299.1 - 9.6e-28 95.8 0.2 8.8e-16 57.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM68299.1 - 7.4e-08 32.4 0.1 0.018 15.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RL PF17797.1 KFM68299.1 - 7.8e-05 22.5 0.0 0.0039 17.1 0.0 2.3 2 0 0 2 2 2 1 RL domain Nup35_RRM_2 PF14605.6 KFM68299.1 - 0.00058 19.8 0.0 0.5 10.4 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Aldo_ket_red PF00248.21 KFM68300.1 - 9.1e-60 202.3 0.0 1.2e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF5580 PF17743.1 KFM68300.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Bacillus_HBL PF05791.11 KFM68301.1 - 0.028 14.2 0.3 0.079 12.8 0.3 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4047 PF13256.6 KFM68301.1 - 0.038 14.2 0.8 0.074 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Cep57_CLD_2 PF14197.6 KFM68301.1 - 0.27 11.4 8.2 0.63 10.2 8.2 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 KxDL PF10241.9 KFM68301.1 - 0.8 10.0 6.1 0.47 10.8 2.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein UPF0242 PF06785.11 KFM68301.1 - 0.81 9.8 7.8 0.093 12.8 2.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Y_phosphatase PF00102.27 KFM68304.1 - 1.8e-47 161.9 0.5 1.8e-47 161.9 0.5 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM68304.1 - 5.9e-06 26.4 0.7 3.4e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KFM68304.1 - 0.074 12.9 0.0 0.074 12.9 0.0 3.8 4 0 0 4 4 4 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFM68304.1 - 0.13 12.4 0.0 0.13 12.4 0.0 3.3 3 0 0 3 3 3 0 Inositol hexakisphosphate BppL_N PF18338.1 KFM68304.1 - 0.14 12.0 0.6 0.41 10.5 0.6 1.8 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain Apolipoprotein PF01442.18 KFM68305.1 - 4.6e-06 26.6 14.0 6.4e-06 26.2 14.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 KFM68305.1 - 0.00089 19.3 16.2 0.023 14.7 4.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFM68305.1 - 0.0011 19.0 1.6 0.45 10.5 0.2 2.1 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KFM68305.1 - 0.0013 17.7 10.1 0.0016 17.4 10.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.9 KFM68305.1 - 0.0075 15.4 4.5 0.0092 15.1 4.5 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Phasin PF05597.11 KFM68305.1 - 0.0079 16.2 19.4 0.22 11.5 4.8 2.2 1 1 1 2 2 2 2 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF725 PF05267.12 KFM68305.1 - 0.031 14.3 4.7 0.46 10.5 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF725) FlaC_arch PF05377.11 KFM68305.1 - 0.047 14.1 2.9 0.047 14.1 2.9 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) ApoO PF09769.9 KFM68305.1 - 0.066 13.2 8.4 0.34 10.9 1.8 2.3 1 1 1 2 2 2 0 Apolipoprotein O Exonuc_VII_L PF02601.15 KFM68305.1 - 0.089 12.4 7.2 0.12 12.0 7.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S64 PF08192.11 KFM68305.1 - 0.093 11.2 5.3 0.11 11.0 5.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 COG2 PF06148.11 KFM68305.1 - 0.094 12.8 18.3 0.59 10.2 4.0 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 KFM68305.1 - 0.11 10.4 7.1 0.14 10.1 7.1 1.0 1 0 0 1 1 1 0 Prominin Bacillus_HBL PF05791.11 KFM68305.1 - 0.15 11.9 8.0 0.91 9.3 4.0 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) BRK PF07533.16 KFM68305.1 - 0.16 11.6 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 BRK domain Glyco_hydro_1 PF00232.18 KFM68305.1 - 0.2 10.0 2.1 0.26 9.7 1.9 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 1 V_ATPase_I PF01496.19 KFM68305.1 - 0.22 9.4 9.5 0.26 9.2 9.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBCC_N PF16752.5 KFM68305.1 - 0.23 11.9 12.1 0.23 11.9 1.2 2.4 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Phage_Mu_Gam PF07352.12 KFM68305.1 - 0.28 11.1 12.7 1.8 8.5 7.7 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein SNARE PF05739.19 KFM68305.1 - 0.35 10.9 3.3 0.51 10.4 0.3 2.7 2 1 1 3 3 3 0 SNARE domain PLAC9 PF15205.6 KFM68305.1 - 0.36 11.3 4.7 0.27 11.7 1.3 2.3 1 1 1 2 2 2 0 Placenta-specific protein 9 CdvA PF18822.1 KFM68305.1 - 0.4 10.5 16.9 0.84 9.5 8.3 2.6 1 1 3 4 4 4 0 CdvA-like coiled-coil domain DUF4890 PF16231.5 KFM68305.1 - 0.46 11.0 12.5 0.059 13.9 6.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4890) DUF4208 PF13907.6 KFM68305.1 - 0.47 10.9 5.0 0.34 11.4 2.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) DUF3584 PF12128.8 KFM68305.1 - 0.51 7.8 14.0 0.7 7.3 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LOH1CR12 PF10158.9 KFM68305.1 - 0.75 9.8 9.1 0.44 10.6 6.7 1.7 1 1 0 1 1 1 0 Tumour suppressor protein DUF5082 PF16888.5 KFM68305.1 - 0.87 9.9 11.7 2 8.7 11.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF713 PF05218.14 KFM68305.1 - 0.87 9.3 9.2 0.19 11.5 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF713) Baculo_p24 PF05073.12 KFM68305.1 - 0.9 9.3 7.7 0.31 10.8 1.9 2.0 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Spectrin PF00435.21 KFM68305.1 - 0.95 10.0 13.7 5.7 7.5 9.7 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF883 PF05957.13 KFM68305.1 - 0.98 10.1 13.8 1.7 9.3 1.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1640 PF07798.11 KFM68305.1 - 1.1 9.2 13.4 2.2 8.3 13.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) LMBR1 PF04791.16 KFM68305.1 - 1.2 8.0 5.0 1.5 7.7 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein KxDL PF10241.9 KFM68305.1 - 2.4 8.5 10.7 3.4 8.0 0.6 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein Tho2 PF11262.8 KFM68305.1 - 3 6.9 9.2 2.1 7.5 7.8 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Strep_SA_rep PF06696.11 KFM68305.1 - 3.1 7.9 11.5 1.8 8.6 0.8 3.3 3 0 0 3 3 3 0 Streptococcal surface antigen repeat ApoLp-III PF07464.11 KFM68305.1 - 3.3 7.8 21.4 1.5 8.9 4.7 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Presenilin PF01080.17 KFM68305.1 - 3.7 6.2 5.6 3.8 6.2 5.6 1.1 1 0 0 1 1 1 0 Presenilin PIN_8 PF18476.1 KFM68305.1 - 6.9 6.5 11.7 7.6 6.3 10.3 1.5 1 1 0 1 1 1 0 PIN like domain Cauli_AT PF03233.13 KFM68305.1 - 7.4 6.5 10.3 20 5.1 10.3 1.7 1 1 0 1 1 1 0 Aphid transmission protein TMPIT PF07851.13 KFM68305.1 - 9.8 5.3 15.1 6.1 6.0 10.8 1.9 1 1 1 2 2 2 0 TMPIT-like protein EF-hand_7 PF13499.6 KFM68306.1 - 5.2e-17 62.1 6.1 3.6e-12 46.6 1.1 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFM68306.1 - 5.7e-16 57.0 2.6 6.1e-07 28.9 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KFM68306.1 - 4e-15 54.1 6.5 2.2e-05 23.7 0.6 4.3 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 KFM68306.1 - 2.8e-08 32.9 3.7 0.00037 19.9 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFM68306.1 - 9.9e-08 31.7 5.1 0.016 15.1 0.3 3.6 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM68306.1 - 1e-06 29.1 0.8 0.00012 22.3 0.6 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFM68306.1 - 0.00077 19.4 0.8 0.0081 16.1 0.7 2.5 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand DIMCO_N PF16844.5 KFM68306.1 - 0.028 14.7 0.1 0.076 13.3 0.1 1.8 1 1 1 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal EF-hand_11 PF08976.11 KFM68306.1 - 0.034 15.0 0.2 6.5 7.7 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain HTH_23 PF13384.6 KFM68306.1 - 0.065 13.0 0.0 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain RST PF12174.8 KFM68306.1 - 0.077 12.9 0.3 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain HLH PF00010.26 KFM68307.1 - 7.2e-16 57.9 0.6 7.2e-16 57.9 0.6 1.7 2 0 0 2 2 1 1 Helix-loop-helix DNA-binding domain Uds1 PF15456.6 KFM68307.1 - 0.00095 19.3 3.6 0.00095 19.3 3.6 1.8 1 1 1 2 2 2 1 Up-regulated During Septation SlyX PF04102.12 KFM68307.1 - 0.0014 19.2 2.6 0.0015 19.1 1.1 1.8 2 0 0 2 2 1 1 SlyX DUF5082 PF16888.5 KFM68307.1 - 0.0019 18.4 1.8 0.0035 17.6 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) JAKMIP_CC3 PF16034.5 KFM68307.1 - 0.0023 17.9 1.3 0.0023 17.9 1.3 1.8 2 0 0 2 2 2 1 JAKMIP CC3 domain DUF5595 PF18077.1 KFM68307.1 - 0.032 14.3 0.5 0.069 13.2 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) TMF_DNA_bd PF12329.8 KFM68307.1 - 0.041 13.9 1.6 0.098 12.7 1.6 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KFM68307.1 - 0.046 14.2 1.4 0.091 13.2 1.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB CCDC106 PF15794.5 KFM68307.1 - 0.047 13.4 8.1 0.019 14.7 4.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 COE1_HLH PF16423.5 KFM68307.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain DUF3847 PF12958.7 KFM68307.1 - 0.093 12.9 0.3 0.093 12.9 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3847) Jnk-SapK_ap_N PF09744.9 KFM68307.1 - 0.13 12.5 3.2 0.2 11.9 3.2 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4577 PF15145.6 KFM68307.1 - 0.13 12.3 1.3 0.22 11.6 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) SLX9 PF15341.6 KFM68307.1 - 0.37 11.2 11.9 1.7 9.0 11.9 1.9 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DivIC PF04977.15 KFM68307.1 - 0.46 10.3 5.1 0.15 11.9 2.1 1.8 2 0 0 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 KFM68307.1 - 0.6 10.2 7.5 0.069 13.2 2.4 2.2 2 1 0 2 2 2 0 Basic region leucine zipper V_ATPase_I PF01496.19 KFM68307.1 - 0.96 7.3 5.6 1.1 7.0 5.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 7tm_1 PF00001.21 KFM68308.1 - 4.8e-21 75.3 10.3 6.3e-21 74.9 10.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFM68308.1 - 3.2e-13 49.7 17.5 5e-13 49.0 17.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFM68308.1 - 2.2e-11 43.6 13.4 3e-11 43.2 13.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFM68308.1 - 0.0001 22.2 6.6 0.0001 22.2 6.6 1.8 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFM68308.1 - 0.0001 22.0 11.2 0.0001 22.0 11.2 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3087 PF11286.8 KFM68308.1 - 0.95 8.9 4.0 0.67 9.4 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) Helicase_C PF00271.31 KFM68309.1 - 4.4e-28 97.8 0.1 2.8e-27 95.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM68309.1 - 2.7e-14 53.3 0.5 1.1e-12 48.1 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KFM68309.1 - 0.027 13.7 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_6 PF14835.6 KFM68311.1 - 3.5e-08 33.2 4.6 6.7e-08 32.3 4.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KFM68311.1 - 5.8e-08 32.5 10.3 1e-07 31.6 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM68311.1 - 4.9e-07 29.5 12.2 9.3e-07 28.6 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM68311.1 - 5.6e-07 29.3 9.5 1.4e-06 28.1 9.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFM68311.1 - 6.9e-06 25.9 11.0 1.5e-05 24.8 11.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM68311.1 - 9.3e-06 25.6 9.7 5.3e-05 23.2 9.7 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 KFM68311.1 - 9e-05 22.5 9.5 0.00011 22.2 8.4 1.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 KFM68311.1 - 0.00019 21.2 12.3 0.00019 21.2 12.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM68311.1 - 0.00048 20.4 11.4 0.00087 19.6 11.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CRD PF17979.1 KFM68311.1 - 0.0011 19.1 5.3 0.0014 18.7 5.3 1.3 1 1 0 1 1 1 1 Cysteine rich domain with multizinc binding regions zf-RING_4 PF14570.6 KFM68311.1 - 0.0013 18.4 4.0 0.0021 17.8 1.7 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFM68311.1 - 0.0014 18.8 9.7 0.009 16.2 10.1 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING RNF220 PF15926.5 KFM68311.1 - 0.013 15.2 0.3 0.019 14.6 0.3 1.4 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 zf-rbx1 PF12678.7 KFM68311.1 - 0.75 10.1 8.5 0.59 10.5 6.2 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain RecR PF02132.15 KFM68311.1 - 2.5 7.7 8.7 11 5.7 0.3 2.7 2 0 0 2 2 2 0 RecR protein zf-C3HC4_5 PF17121.5 KFM68311.1 - 9.5 6.2 11.3 7.2 6.6 3.9 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BRCT PF00533.26 KFM68312.1 - 2.9e-11 43.6 0.5 1.9e-07 31.4 0.9 2.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFM68312.1 - 9.1e-10 38.8 0.1 0.00084 19.7 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFM68312.1 - 5.9e-05 22.9 0.2 0.0001 22.1 0.2 1.3 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Ank_5 PF13857.6 KFM68312.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) COMM_domain PF07258.14 KFM68313.1 - 8e-10 38.7 1.2 1e-09 38.3 0.2 1.7 2 0 0 2 2 2 1 COMM domain zf-HIT PF04438.16 KFM68315.1 - 0.45 10.4 10.1 0.27 11.2 4.4 2.5 2 1 0 2 2 2 0 HIT zinc finger Tom37 PF10568.9 KFM68316.1 - 4.4e-28 98.1 0.0 7.2e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KFM68316.1 - 3.6e-25 87.5 0.2 6.6e-25 86.7 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFM68316.1 - 1.2e-23 83.7 0.0 2.2e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KFM68316.1 - 9.5e-07 28.8 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM68316.1 - 0.081 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-H2C2_2 PF13465.6 KFM68317.1 - 1.6e-30 104.2 55.5 7.2e-06 26.2 0.2 7.4 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68317.1 - 5.3e-30 102.2 55.2 6e-06 26.4 4.2 6.9 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68317.1 - 8.7e-18 63.5 56.0 0.0013 19.4 3.3 7.1 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM68317.1 - 1.1e-09 38.0 42.4 0.0012 18.8 3.3 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM68317.1 - 4.2e-07 30.1 36.3 0.11 12.9 0.6 6.6 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 KFM68317.1 - 0.0019 18.9 17.4 1.3 9.9 1.1 3.4 2 1 1 3 3 3 3 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM68317.1 - 0.0098 16.0 23.8 0.33 11.1 2.9 4.4 2 1 4 6 6 6 3 Zinc ribbon domain zf-met PF12874.7 KFM68317.1 - 0.013 15.8 33.9 0.046 14.1 0.4 6.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type OrfB_Zn_ribbon PF07282.11 KFM68317.1 - 0.08 12.9 0.2 0.08 12.9 0.2 5.1 2 1 4 6 6 6 0 Putative transposase DNA-binding domain zf-Di19 PF05605.12 KFM68317.1 - 0.093 13.0 34.6 0.49 10.7 6.3 4.4 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 KFM68317.1 - 0.093 13.0 13.3 9.4 6.6 0.2 5.0 5 1 0 5 5 5 0 zinc-ribbon zf_UBZ PF18439.1 KFM68317.1 - 0.13 11.9 0.1 0.13 11.9 0.1 5.9 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger BolA PF01722.18 KFM68317.1 - 0.14 12.5 2.5 15 5.9 0.1 2.9 2 2 0 2 2 2 0 BolA-like protein XPA_N PF01286.18 KFM68317.1 - 0.14 12.2 14.7 23 5.1 0.1 6.1 6 0 0 6 6 6 0 XPA protein N-terminal FYDLN_acid PF09538.10 KFM68317.1 - 0.33 11.7 9.8 48 4.7 1.9 4.7 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) GAGA PF09237.11 KFM68317.1 - 0.41 10.5 11.3 2.1 8.2 0.1 4.5 2 2 3 5 5 5 0 GAGA factor Mut7-C PF01927.16 KFM68317.1 - 0.42 10.7 0.0 0.42 10.7 0.0 4.0 2 1 2 4 4 4 0 Mut7-C RNAse domain zf-C2H2_3rep PF18868.1 KFM68317.1 - 0.44 11.2 22.1 3.9 8.2 0.2 5.1 1 1 4 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFM68317.1 - 0.48 10.2 0.1 0.48 10.2 0.1 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFM68317.1 - 0.89 9.4 13.1 6 6.8 0.1 4.8 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) TF_Zn_Ribbon PF08271.12 KFM68317.1 - 1.2 8.7 14.7 2.1 7.9 0.0 4.7 4 1 1 5 5 5 0 TFIIB zinc-binding FYVE PF01363.21 KFM68317.1 - 1.6 8.9 35.5 11 6.3 4.4 3.8 1 1 2 3 3 3 0 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 KFM68317.1 - 1.7 8.8 20.7 0.67 10.1 2.1 5.2 3 3 2 5 5 5 0 Sec23/Sec24 zinc finger Acetone_carb_G PF08882.11 KFM68317.1 - 1.7 8.8 8.0 14 5.8 0.0 3.5 1 1 2 4 4 4 0 Acetone carboxylase gamma subunit ADK_lid PF05191.14 KFM68317.1 - 3.7 7.6 33.5 0.1 12.6 1.4 5.2 3 2 2 5 5 5 0 Adenylate kinase, active site lid zf-GRF PF06839.12 KFM68318.1 - 8.7e-09 35.3 2.3 2.6e-08 33.8 2.3 1.8 1 0 0 1 1 1 1 GRF zinc finger SLM4 PF16818.5 KFM68318.1 - 0.0072 16.3 1.4 0.011 15.8 1.4 1.2 1 0 0 1 1 1 1 Protein SLM4 Vert_IL3-reg_TF PF06529.11 KFM68318.1 - 0.0082 15.3 2.7 0.011 14.8 2.7 1.1 1 0 0 1 1 1 1 Vertebrate interleukin-3 regulated transcription factor Exo_endo_phos PF03372.23 KFM68320.1 - 1.1e-06 28.3 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cnd1 PF12717.7 KFM68320.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HTH_Tnp_Tc3_2 PF01498.18 KFM68321.1 - 4.2e-16 58.9 3.5 5.6e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68321.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68321.1 - 4.3e-08 32.8 1.8 1.1e-07 31.5 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68321.1 - 0.00074 19.2 0.6 0.0021 17.8 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68321.1 - 0.012 15.7 0.5 0.038 14.1 0.5 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM68321.1 - 0.77 10.4 15.9 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_1 PF03184.19 KFM68323.1 - 2.3e-14 53.4 0.1 2.6e-14 53.2 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PP2C PF00481.21 KFM68324.1 - 4.2e-34 118.3 0.0 6.5e-18 65.3 0.0 3.4 3 1 0 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.12 KFM68324.1 - 0.00022 21.2 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Iso_dh PF00180.20 KFM68325.1 - 8.9e-66 222.4 0.0 1.1e-65 222.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Castor1_N PF18700.1 KFM68326.1 - 0.082 12.8 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Fasciclin PF02469.22 KFM68327.1 - 3.7e-90 298.8 0.0 4.5e-24 85.1 0.0 4.2 4 0 0 4 4 4 4 Fasciclin domain Voltage_CLC PF00654.20 KFM68328.1 - 6.2e-61 206.6 22.7 8.3e-61 206.2 22.7 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KFM68328.1 - 2.5e-07 31.0 0.5 0.00016 22.1 0.1 2.6 2 0 0 2 2 2 2 CBS domain THAP PF05485.12 KFM68330.1 - 9.9e-12 45.6 5.9 1.2e-11 45.3 5.9 1.1 1 0 0 1 1 1 1 THAP domain CxC6 PF18721.1 KFM68330.1 - 0.0085 16.3 4.6 0.015 15.5 2.6 2.0 1 1 1 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases DDE_3 PF13358.6 KFM68331.1 - 6.3e-15 55.2 0.1 3.6e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68331.1 - 1.2e-08 34.6 0.1 1.2e-08 34.6 0.1 2.9 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM68331.1 - 1.8e-05 24.9 0.7 3.8e-05 23.8 0.7 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_1 PF11427.8 KFM68331.1 - 0.00035 20.4 0.1 0.0006 19.6 0.1 1.4 1 0 0 1 1 1 1 Tc3 transposase HTH_32 PF13565.6 KFM68331.1 - 0.017 15.7 0.0 0.38 11.4 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 KFM68331.1 - 0.028 14.4 0.3 0.34 10.9 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn helix UreF PF01730.16 KFM68333.1 - 3.9e-08 34.0 0.2 6.4e-08 33.3 0.2 1.3 1 1 0 1 1 1 1 UreF p450 PF00067.22 KFM68335.1 - 7.4e-17 61.2 0.0 9e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_Tnp_Tc3_2 PF01498.18 KFM68336.1 - 2.5e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68336.1 - 9.1e-14 51.4 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68337.1 - 4.2e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68337.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68337.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68337.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68337.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Comm PF15957.5 KFM68338.1 - 0.013 15.8 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 0 Commissureless DUF4719 PF15843.5 KFM68338.1 - 0.017 15.3 0.1 0.021 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Sigma_reg_N PF13800.6 KFM68338.1 - 0.078 13.3 0.5 0.12 12.7 0.5 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Pkinase_Tyr PF07714.17 KFM68338.1 - 0.096 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Shisa PF13908.6 KFM68338.1 - 0.12 12.6 0.2 0.14 12.4 0.2 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KFM68338.1 - 0.14 13.0 0.0 0.15 13.0 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 KFM68339.1 - 2.7e-08 33.5 0.0 4.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM68339.1 - 1.5e-06 27.7 0.0 9.9e-06 25.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Vps16_N PF04841.13 KFM68340.1 - 2.9e-107 359.0 0.0 4.4e-107 358.4 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KFM68340.1 - 1.4e-90 303.7 10.0 1.9e-90 303.1 10.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region CHASE2 PF05226.11 KFM68340.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 CHASE2 domain DDE_3 PF13358.6 KFM68341.1 - 5.6e-16 58.6 0.1 6.2e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68341.1 - 7.9e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68341.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68341.1 - 0.0027 17.4 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68341.1 - 0.017 15.3 0.1 0.067 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68341.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix 2OG-FeII_Oxy_2 PF13532.6 KFM68342.1 - 3.4e-35 122.0 0.0 4.2e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dynein_IC2 PF11540.8 KFM68343.1 - 1.1e-12 47.7 4.0 1.1e-12 47.7 4.0 1.8 2 0 0 2 2 2 1 Cytoplasmic dynein 1 intermediate chain 2 RLL PF10036.9 KFM68343.1 - 0.02 14.7 0.9 0.019 14.8 0.9 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Mif2_N PF15624.6 KFM68343.1 - 2.7 8.7 9.2 2.8 8.7 8.6 1.3 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal WD40 PF00400.32 KFM68344.1 - 7.7e-09 36.1 18.2 0.02 15.8 1.6 7.4 7 0 0 7 7 7 3 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 KFM68344.1 - 0.0018 17.6 0.0 0.0046 16.3 0.0 1.6 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ANAPC4_WD40 PF12894.7 KFM68344.1 - 0.037 14.3 0.0 2.2 8.6 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Homeodomain PF00046.29 KFM68345.1 - 3.7e-22 77.9 8.2 7.6e-22 76.9 8.2 1.6 1 0 0 1 1 1 1 Homeodomain Paf1 PF03985.13 KFM68346.1 - 2.5e-11 43.2 2.5 2.8e-11 43.1 2.5 1.1 1 0 0 1 1 1 1 Paf1 Peptidase_C97 PF05903.14 KFM68347.1 - 6.5e-14 52.0 0.0 7.1e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_C97 PF05903.14 KFM68348.1 - 5.4e-12 45.8 0.2 6.3e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain Uteroglobin PF01099.17 KFM68349.1 - 0.085 13.2 0.0 0.086 13.2 0.0 1.0 1 0 0 1 1 1 0 Uteroglobin family HTH_Tnp_Tc3_2 PF01498.18 KFM68350.1 - 4.9e-16 58.7 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68350.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68350.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68350.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68350.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68351.1 - 2.1e-19 69.5 3.6 5.5e-19 68.2 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68351.1 - 4.4e-16 59.0 0.0 2.2e-15 56.7 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM68351.1 - 3.5e-07 30.8 2.0 3.5e-07 30.8 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KFM68351.1 - 3.6e-07 30.1 1.1 0.00014 21.9 0.0 2.7 3 0 0 3 3 2 2 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM68351.1 - 9.2e-07 28.9 2.3 7.4e-05 22.8 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68351.1 - 1.7e-06 27.6 3.4 2.4e-05 24.0 0.0 3.0 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM68351.1 - 2.7e-06 27.3 0.7 3.9e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM68351.1 - 0.0001 22.1 0.5 0.0016 18.3 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM68351.1 - 0.0011 18.9 0.3 0.016 15.2 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM68351.1 - 0.02 14.5 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM68351.1 - 0.048 13.7 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM68351.1 - 0.066 13.4 0.1 12 6.2 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM68351.1 - 0.14 11.7 0.2 0.79 9.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM68351.1 - 0.17 12.0 0.0 29 4.8 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM68351.1 - 0.28 11.0 3.9 1.4 8.8 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM68351.1 - 0.96 8.9 3.6 7 6.2 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 GMP_PDE_delta PF05351.11 KFM68352.1 - 1.1e-10 41.8 0.1 2.5e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 GMP-PDE, delta subunit GMP_PDE_delta PF05351.11 KFM68353.1 - 1.6e-41 142.0 2.5 1.7e-41 141.9 2.5 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit Ribosomal_L24e PF01246.20 KFM68354.1 - 1.2e-31 108.7 5.2 2.7e-31 107.6 5.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DUF3318 PF11780.8 KFM68354.1 - 0.0085 16.0 0.2 0.011 15.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3318) Seryl_tRNA_N PF02403.22 KFM68355.1 - 0.018 15.3 1.0 0.022 15.0 1.0 1.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 KFM68355.1 - 0.11 12.6 1.4 0.11 12.5 1.4 1.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_S6e PF01092.19 KFM68356.1 - 3.6e-27 94.8 0.1 3.6e-27 94.8 0.1 1.9 2 1 0 2 2 2 1 Ribosomal protein S6e zf-CCHC_4 PF14392.6 KFM68357.1 - 0.021 14.6 8.9 0.36 10.6 1.5 2.7 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 KFM68357.1 - 7.4 6.8 16.0 0.63 10.2 0.5 3.1 4 0 0 4 4 4 0 Zinc knuckle DDE_3 PF13358.6 KFM68359.1 - 4.9e-16 58.8 0.1 5.6e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68359.1 - 7.7e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68359.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain CLIP1_ZNF PF16641.5 KFM68360.1 - 1.7e-12 46.8 14.9 1.5e-07 31.1 5.6 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle DAP3 PF10236.9 KFM68360.1 - 0.084 12.0 0.3 0.084 12.0 0.3 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 UPF0184 PF03670.13 KFM68360.1 - 2.4 8.6 7.2 0.45 10.9 1.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) zf-U1 PF06220.12 KFM68360.1 - 8.1 6.3 6.7 2 8.3 1.7 2.1 2 0 0 2 2 2 0 U1 zinc finger MSA-2c PF12238.8 KFM68360.1 - 8.3 6.4 9.5 14 5.6 9.5 1.5 1 1 0 1 1 1 0 Merozoite surface antigen 2c zf-H2C2_2 PF13465.6 KFM68361.1 - 4.9e-44 146.9 75.4 4.6e-09 36.3 1.9 9.8 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68361.1 - 1.6e-27 94.3 87.7 0.00014 22.1 3.1 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68361.1 - 3.7e-25 86.4 81.1 0.0013 19.4 1.0 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM68361.1 - 9.7e-13 47.8 64.7 0.0028 17.6 2.9 9.2 9 0 0 9 9 9 7 C2H2-type zinc finger zf-met PF12874.7 KFM68361.1 - 1.1e-07 32.0 71.6 0.027 14.9 4.2 9.6 9 1 0 9 9 9 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM68361.1 - 1.9e-07 31.2 67.7 0.12 12.7 0.5 9.3 9 0 0 9 9 9 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM68361.1 - 0.00026 21.2 13.3 0.036 14.3 0.1 5.6 2 2 2 4 4 4 1 BolA-like protein C1_1 PF00130.22 KFM68361.1 - 0.0046 16.8 52.5 0.1 12.5 2.1 7.7 4 2 3 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM68361.1 - 0.01 15.6 14.5 3.3 7.6 0.3 5.9 2 1 4 6 6 6 0 GAGA factor DUF2256 PF10013.9 KFM68361.1 - 0.072 13.2 34.3 5.3 7.2 0.2 8.6 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KFM68361.1 - 0.15 12.4 61.7 1.7 9.0 0.7 8.5 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) Scramblase PF03803.15 KFM68361.1 - 0.29 10.4 11.4 1.3 8.2 2.1 2.6 1 1 2 3 3 3 0 Scramblase ADK_lid PF05191.14 KFM68361.1 - 0.34 10.9 0.1 0.34 10.9 0.1 5.3 4 3 1 5 5 4 0 Adenylate kinase, active site lid zf-C2H2_9 PF16293.5 KFM68361.1 - 0.6 10.0 35.1 6.6 6.7 0.2 8.5 4 3 5 9 9 9 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM68361.1 - 4.5 7.3 45.6 5.2 7.1 2.8 8.2 7 1 1 8 8 8 0 zinc-finger of a C2HC-type TRAF6_Z2 PF18048.1 KFM68361.1 - 6.2 7.0 30.8 4.4 7.5 0.4 7.1 7 0 0 7 7 7 0 TNF receptor-associated factor 6 zinc finger 2 DDE_3 PF13358.6 KFM68362.1 - 2.7e-15 56.4 0.0 3.8e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease EamA PF00892.20 KFM68363.1 - 4.8e-10 39.8 29.6 6.9e-08 32.8 10.5 2.6 2 1 0 2 2 2 2 EamA-like transporter family DoxX_2 PF13564.6 KFM68363.1 - 0.0008 19.5 3.0 0.0008 19.5 3.0 3.0 1 1 2 3 3 3 1 DoxX-like family XRN_M PF17846.1 KFM68363.1 - 0.15 11.0 2.7 0.2 10.5 2.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain YabA PF06156.13 KFM68363.1 - 0.16 12.6 1.1 0.3 11.8 1.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA CLZ PF16526.5 KFM68363.1 - 0.23 11.8 0.9 0.38 11.1 0.9 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels COG2 PF06148.11 KFM68363.1 - 0.24 11.5 1.8 0.4 10.8 1.8 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3087 PF11286.8 KFM68363.1 - 0.39 10.2 2.4 0.61 9.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Rax2 PF12768.7 KFM68363.1 - 1.8 7.9 4.9 0.62 9.5 0.3 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity EPL1 PF10513.9 KFM68363.1 - 1.9 8.9 5.4 2.9 8.3 5.4 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4758 PF15950.5 KFM68363.1 - 2.8 8.3 5.5 5.8 7.3 5.5 1.5 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein DUF1980 PF09323.10 KFM68363.1 - 3.6 7.5 5.6 3.9 7.3 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1980) DDE_3 PF13358.6 KFM68364.1 - 5.1e-16 58.7 0.1 6.3e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68364.1 - 7.8e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM68364.1 - 0.00069 19.3 0.0 0.029 14.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68364.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68364.1 - 0.012 15.7 0.1 0.049 13.8 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68364.1 - 0.023 14.7 2.1 0.033 14.2 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM68364.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase EamA PF00892.20 KFM68365.1 - 2.7e-15 56.7 32.1 6.4e-13 49.0 10.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family Rax2 PF12768.7 KFM68365.1 - 0.013 15.0 0.2 0.028 13.9 0.2 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EamA PF00892.20 KFM68366.1 - 3.7e-19 69.3 22.5 2e-17 63.6 8.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 KFM68366.1 - 6.3e-07 29.2 11.9 8.3e-07 28.8 11.9 1.1 1 0 0 1 1 1 1 Solute carrier family 35 TPT PF03151.16 KFM68366.1 - 3.1e-06 26.7 3.1 3.1e-06 26.7 3.1 1.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 KFM68366.1 - 0.00059 18.9 6.8 0.00066 18.7 5.8 1.6 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Lysis_col PF02402.16 KFM68366.1 - 0.022 14.4 0.6 0.088 12.5 0.1 2.3 2 0 0 2 2 2 0 Lysis protein DUF2085 PF09858.9 KFM68366.1 - 5.3 7.6 8.1 0.37 11.3 0.2 2.7 2 1 2 4 4 4 0 Predicted membrane protein (DUF2085) DDE_3 PF13358.6 KFM68367.1 - 1.4e-14 54.0 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease WW PF00397.26 KFM68368.1 - 1.3e-09 38.0 1.7 3.7e-09 36.5 1.7 1.8 1 0 0 1 1 1 1 WW domain Ank_4 PF13637.6 KFM68369.1 - 4.1e-41 138.8 4.8 2.6e-10 40.6 0.1 7.5 5 1 3 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM68369.1 - 1.1e-40 138.1 9.9 2.6e-14 53.6 0.2 6.3 2 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM68369.1 - 2.9e-37 122.4 9.0 2.8e-05 24.2 0.0 9.7 8 1 0 8 8 8 8 Ankyrin repeat Ank PF00023.30 KFM68369.1 - 8.7e-36 120.8 12.2 5.8e-05 23.3 0.1 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 KFM68369.1 - 3.3e-27 94.2 11.6 8.9e-06 25.9 0.1 8.7 3 2 5 8 8 8 7 Ankyrin repeats (many copies) HTH_Tnp_Tc3_2 PF01498.18 KFM68370.1 - 4.3e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68370.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68370.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68370.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68370.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ketoacyl-synt PF00109.26 KFM68371.1 - 1.1e-56 192.2 0.5 9.8e-56 189.1 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFM68371.1 - 6e-33 113.4 0.6 1.7e-32 111.9 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFM68371.1 - 0.0031 16.9 0.0 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain STAS PF01740.21 KFM68371.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 STAS domain ACP_syn_III PF08545.10 KFM68371.1 - 0.34 10.8 2.5 6.7 6.6 0.4 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MCU PF04678.13 KFM68372.1 - 0.3 11.2 3.2 0.45 10.6 3.2 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter MAT1 PF06391.13 KFM68372.1 - 0.37 10.6 8.1 0.58 9.9 8.1 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 HTH_Tnp_Tc3_2 PF01498.18 KFM68373.1 - 4.8e-16 58.8 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68373.1 - 7.1e-14 51.8 0.0 2.2e-13 50.2 0.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68373.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68373.1 - 0.0027 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68373.1 - 2.1 9.0 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Methyltransf_34 PF11312.8 KFM68374.1 - 3.7e-07 29.7 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Methyltransf_2 PF00891.18 KFM68374.1 - 0.063 12.6 0.7 0.16 11.2 0.1 1.9 2 1 0 2 2 2 0 O-methyltransferase domain HEPN_DZIP3 PF18738.1 KFM68374.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN Methyltransf_34 PF11312.8 KFM68375.1 - 1.1e-09 38.0 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase LETM1 PF07766.13 KFM68375.1 - 0.022 14.1 0.8 0.037 13.4 0.1 1.7 2 0 0 2 2 2 0 LETM1-like protein NAD_binding_10 PF13460.6 KFM68375.1 - 0.17 11.7 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Aa_trans PF01490.18 KFM68376.1 - 1.4e-61 208.5 25.9 1.6e-61 208.2 25.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein L6_membrane PF05805.12 KFM68376.1 - 0.023 14.3 0.7 0.023 14.3 0.7 2.7 3 0 0 3 3 3 0 L6 membrane protein DUF4407 PF14362.6 KFM68376.1 - 1.1 8.6 2.8 2.7 7.3 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDE_3 PF13358.6 KFM68377.1 - 6.2e-10 39.0 0.0 8.3e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Mito_carr PF00153.27 KFM68378.1 - 1.9e-15 56.5 0.1 3.4e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein SpoIIM PF01944.17 KFM68378.1 - 0.26 11.3 3.0 0.4 10.7 3.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein M TTL PF03133.15 KFM68379.1 - 5.6e-57 193.1 0.6 1.2e-56 192.0 0.6 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family 4HB_MCP_1 PF12729.7 KFM68379.1 - 0.016 14.7 0.4 0.028 14.0 0.4 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF1752 PF08550.10 KFM68379.1 - 0.077 12.9 0.1 13 5.7 0.0 3.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1752) fn3_4 PF16794.5 KFM68380.1 - 4.9e-31 106.7 0.1 1.2e-30 105.4 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-III type domain fn3 PF00041.21 KFM68380.1 - 0.00044 20.5 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DDE_3 PF13358.6 KFM68381.1 - 0.068 12.9 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF1794 PF08768.11 KFM68382.1 - 9.7e-31 106.7 0.0 1.1e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) DDE_3 PF13358.6 KFM68383.1 - 7.5e-08 32.3 0.0 9.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_92 PF01697.27 KFM68383.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 Actin PF00022.19 KFM68384.1 - 3.1e-23 82.1 0.0 3.7e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Actin PilM_2 PF11104.8 KFM68384.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; DUF3498 PF12004.8 KFM68385.1 - 3.8e-10 39.6 15.3 7.1e-10 38.7 15.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) PknG_rubred PF16919.5 KFM68385.1 - 0.049 13.8 0.6 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain DUF4407 PF14362.6 KFM68385.1 - 1.2 8.5 9.0 2.1 7.6 8.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 KFM68385.1 - 2.2 8.1 22.4 1.5 8.6 15.3 3.0 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Acyltransferase PF01553.21 KFM68386.1 - 8.5e-30 103.1 0.0 1e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase DDE_1 PF03184.19 KFM68387.1 - 8.7e-39 133.0 0.2 1.6e-38 132.1 0.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM68387.1 - 5.4e-15 55.2 0.3 1.5e-14 53.8 0.3 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM68387.1 - 1.1e-05 24.9 2.5 3.9e-05 23.2 2.5 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFM68387.1 - 0.0043 16.8 0.1 0.015 15.1 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_psq PF05225.16 KFM68387.1 - 0.024 14.3 0.0 0.075 12.8 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain zf-H2C2_2 PF13465.6 KFM68388.1 - 2.3e-85 277.5 87.0 5.9e-08 32.8 0.6 13.4 12 1 1 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68388.1 - 1.2e-48 160.9 108.4 5.9e-06 26.5 3.9 12.2 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68388.1 - 4.2e-43 142.3 101.5 0.00038 21.0 0.3 12.2 12 0 0 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM68388.1 - 9.8e-30 102.1 83.0 0.0018 18.6 2.2 12.6 12 0 0 12 12 12 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM68388.1 - 2.9e-24 84.8 60.8 0.004 17.4 0.9 12.5 11 1 1 12 12 12 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM68388.1 - 1.1e-19 70.0 81.7 0.0072 16.3 0.4 12.9 12 1 0 12 12 12 9 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM68388.1 - 7.1e-09 35.4 51.1 0.32 10.9 0.1 11.3 4 4 8 12 12 12 6 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 KFM68388.1 - 3.1e-05 23.9 44.6 0.5 10.4 0.4 7.1 5 1 2 7 7 7 6 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM68388.1 - 3.3e-05 24.2 82.3 1.3 9.4 0.8 11.4 1 1 9 10 10 10 6 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 KFM68388.1 - 3.8e-05 23.6 14.1 33 4.7 0.0 9.7 11 0 0 11 11 11 0 Zinc-finger domain zf-RRPl_C4 PF17026.5 KFM68388.1 - 6.9e-05 22.9 44.6 0.081 13.0 2.7 5.0 1 1 5 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type zf-Sec23_Sec24 PF04810.15 KFM68388.1 - 0.00037 20.5 42.3 3 8.0 0.0 11.2 10 2 2 12 12 12 1 Sec23/Sec24 zinc finger Tox-HNH-HHH PF15637.6 KFM68388.1 - 0.008 16.3 0.6 34 4.6 0.0 4.6 1 1 2 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-MYST PF17772.1 KFM68388.1 - 0.042 13.4 0.2 0.042 13.4 0.2 10.3 6 5 6 12 12 12 0 MYST family zinc finger domain NAD_kinase PF01513.21 KFM68388.1 - 0.1 11.7 1.9 20 4.2 1.9 3.9 1 1 0 1 1 1 0 ATP-NAD kinase BHD_1 PF10403.9 KFM68388.1 - 0.12 12.2 1.1 6 6.8 0.0 3.4 4 0 0 4 4 3 0 Rad4 beta-hairpin domain 1 zinc_ribbon_15 PF17032.5 KFM68388.1 - 0.14 13.0 44.3 1.1 10.0 0.2 6.3 3 2 3 6 6 6 0 zinc-ribbon family TRAF6_Z2 PF18048.1 KFM68388.1 - 0.31 11.2 42.3 1.2 9.3 0.2 10.3 10 0 0 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2HC_2 PF13913.6 KFM68388.1 - 0.35 10.8 49.8 12 6.0 0.7 11.6 12 0 0 12 12 12 0 zinc-finger of a C2HC-type PqqA PF08042.11 KFM68388.1 - 0.42 10.7 0.8 6.2e+02 0.7 0.0 4.8 5 0 0 5 5 5 0 PqqA family DUF2256 PF10013.9 KFM68388.1 - 2.5 8.3 48.5 4.3 7.5 0.1 11.4 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) C5HCH PF17982.1 KFM68388.1 - 2.8 8.2 61.3 3.3 7.9 0.8 11.4 6 1 5 12 12 12 0 NSD Cys-His rich domain FYVE PF01363.21 KFM68388.1 - 5.2 7.3 68.0 0.79 9.9 10.9 6.8 1 1 3 6 6 6 0 FYVE zinc finger zf-DBF PF07535.12 KFM68388.1 - 7.4 6.8 56.1 21 5.3 0.5 11.3 11 1 1 12 12 12 0 DBF zinc finger CBS PF00571.28 KFM68391.1 - 1.3e-14 54.4 1.9 4.3e-06 27.1 0.0 3.1 4 0 0 4 4 4 2 CBS domain DDE_3 PF13358.6 KFM68394.1 - 1.9e-16 60.1 0.1 1.8e-15 56.9 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68394.1 - 1.7e-10 41.0 1.0 3e-10 40.2 1.0 1.4 1 0 0 1 1 1 1 Transposase C2-set_2 PF08205.12 KFM68395.1 - 1e-06 28.7 0.0 1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM68395.1 - 0.00013 22.5 0.0 0.00013 22.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM68395.1 - 0.00019 21.7 0.0 0.0002 21.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM68395.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.25 KFM68395.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain Peptidase_A17 PF05380.13 KFM68396.1 - 2.6e-51 173.8 0.1 5e-51 172.9 0.1 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF5641 PF18701.1 KFM68396.1 - 5.1e-24 84.3 0.1 1.2e-23 83.1 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 KFM68396.1 - 1.8e-10 40.7 2.7 1.8e-10 40.7 2.7 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KFM68396.1 - 3.4e-09 36.9 0.0 7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KFM68396.1 - 0.00061 20.0 0.9 0.0019 18.3 0.9 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Ig_3 PF13927.6 KFM68397.1 - 3.7e-06 27.4 0.0 3.7e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM68397.1 - 2.6e-05 24.2 0.0 2.6e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM68397.1 - 0.00016 21.7 0.0 0.00016 21.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM68397.1 - 0.00025 21.3 0.0 0.00026 21.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM68397.1 - 0.00033 20.7 0.0 0.00033 20.7 0.0 1.0 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain E1-E2_ATPase PF00122.20 KFM68400.1 - 7e-45 152.8 0.8 6.6e-44 149.6 0.3 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFM68400.1 - 1.1e-42 145.9 0.0 1.1e-42 145.9 0.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFM68400.1 - 3.5e-21 76.5 0.2 4.2e-11 43.5 0.0 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFM68400.1 - 1.9e-20 72.7 0.1 3.5e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFM68400.1 - 2e-18 65.8 0.0 3.7e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFM68400.1 - 1.4e-06 28.3 1.2 0.00082 19.2 0.5 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM68400.1 - 0.009 16.4 0.2 0.092 13.1 0.1 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 KFM68400.1 - 0.78 8.4 3.7 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) HTH_psq PF05225.16 KFM68403.1 - 0.13 12.0 0.3 0.58 9.9 0.1 1.9 1 1 1 2 2 2 0 helix-turn-helix, Psq domain Bac_small_YrzI PF09501.10 KFM68403.1 - 1.4 9.2 7.2 3.3 7.9 0.4 2.1 1 1 1 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Carn_acyltransf PF00755.20 KFM68406.1 - 6.5e-161 536.9 0.0 7.3e-161 536.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DNA_pol_B_exo1 PF03104.19 KFM68408.1 - 3.6e-78 263.1 3.5 6.3e-78 262.3 3.5 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KFM68408.1 - 1e-15 57.5 0.8 3.7e-14 52.3 0.7 3.2 2 1 0 2 2 2 1 DNA polymerase family B RNase_H_2 PF13482.6 KFM68408.1 - 2.5e-08 34.1 0.3 1.1e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KFM68408.1 - 3.4e-08 33.4 2.4 1.5e-07 31.4 1.5 2.3 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB APP_N PF02177.16 KFM68408.1 - 0.0011 19.3 0.3 0.0026 18.1 0.3 1.6 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding Kinase-PPPase PF03618.14 KFM68408.1 - 0.026 14.3 1.0 0.86 9.3 0.7 3.0 2 1 0 2 2 2 0 Kinase/pyrophosphorylase NAPRTase_C PF17956.1 KFM68408.1 - 0.15 12.5 0.8 0.68 10.4 0.0 2.5 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF1744 PF08490.12 KFM68409.1 - 4.4e-131 437.2 0.0 8e-131 436.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) GPS PF01825.21 KFM68414.1 - 7e-10 39.3 7.5 1.1e-09 38.6 7.5 1.4 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif PKD_channel PF08016.12 KFM68416.1 - 1.7e-32 112.7 17.5 2e-32 112.4 17.5 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFM68416.1 - 7.7e-13 48.2 20.0 2.3e-12 46.7 20.0 1.7 1 1 0 1 1 1 1 Ion transport protein PspB PF06667.12 KFM68416.1 - 2.8 8.0 5.1 1.3 9.1 1.6 2.1 2 0 0 2 2 2 0 Phage shock protein B Glucosamine_iso PF01182.20 KFM68417.1 - 3.1e-68 230.0 0.0 3.5e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SKIP_SNW PF02731.15 KFM68418.1 - 1.6e-74 248.9 6.2 1.6e-74 248.9 6.2 2.7 3 0 0 3 3 3 1 SKIP/SNW domain HTH_Tnp_Tc3_2 PF01498.18 KFM68419.1 - 2.6e-15 56.4 1.5 6.3e-15 55.2 1.5 1.6 1 0 0 1 1 1 1 Transposase HTH_IclR PF09339.10 KFM68419.1 - 0.0018 18.1 0.0 0.0052 16.6 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_32 PF13565.6 KFM68419.1 - 0.0033 18.0 9.8 0.37 11.4 3.1 3.0 3 0 0 3 3 3 2 Homeodomain-like domain FeoC PF09012.10 KFM68419.1 - 0.19 11.8 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator PDCD2_C PF04194.13 KFM68421.1 - 3.4e-48 164.0 4.1 4.3e-47 160.4 1.2 2.7 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 KFM68421.1 - 0.00034 20.6 15.7 0.00034 20.6 15.7 3.4 3 1 0 3 3 3 1 MYND finger DUF842 PF05811.13 KFM68422.1 - 2.7e-47 159.8 15.6 3.1e-47 159.5 15.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) RasGAP_C PF03836.15 KFM68422.1 - 0.00048 20.3 1.5 0.00072 19.7 0.6 1.7 1 1 1 2 2 2 1 RasGAP C-terminus ACDC PF14733.6 KFM68422.1 - 0.00064 20.0 7.0 0.0039 17.5 4.9 2.6 1 1 0 2 2 2 1 AP2-coincident C-terminal MukF_M PF17192.4 KFM68422.1 - 0.0037 17.0 3.1 0.0039 16.9 2.7 1.3 1 1 0 1 1 1 1 MukF middle domain HOIP-UBA PF16678.5 KFM68422.1 - 0.0066 16.5 0.5 0.02 14.9 0.4 1.8 1 1 1 2 2 2 1 HOIP UBA domain pair FAM184 PF15665.5 KFM68422.1 - 0.015 15.1 0.1 0.017 14.9 0.1 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B ING PF12998.7 KFM68422.1 - 0.036 14.6 1.2 0.27 11.8 0.4 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF5082 PF16888.5 KFM68422.1 - 0.05 13.9 1.0 0.11 12.7 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) ApoLp-III PF07464.11 KFM68422.1 - 0.07 13.2 0.2 0.54 10.3 0.1 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 KFM68422.1 - 0.085 12.9 0.4 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ANAPC4 PF12896.7 KFM68422.1 - 0.096 12.2 2.1 0.54 9.7 1.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Muted PF14942.6 KFM68422.1 - 0.26 11.6 5.5 0.33 11.3 4.2 1.7 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Vicilin_N PF04702.12 KFM68422.1 - 0.58 10.0 12.6 1.1 9.0 12.4 1.6 1 1 0 1 1 1 0 Vicilin N terminal region Vanabin-2 PF11437.8 KFM68422.1 - 1.4 9.1 19.1 24 5.1 16.6 2.5 1 1 1 2 2 2 0 Vanadium-binding protein 2 PIG-X PF08320.12 KFM68423.1 - 5.8e-06 26.4 0.0 6.2e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 zf-H2C2_2 PF13465.6 KFM68424.1 - 2.1e-50 167.0 72.7 2.1e-07 31.1 1.0 9.8 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68424.1 - 3.7e-33 112.1 98.9 8.3e-05 22.8 5.0 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68424.1 - 2.8e-28 96.2 92.6 0.0013 19.4 4.2 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM68424.1 - 1.2e-19 70.0 83.4 0.00012 22.4 4.2 9.5 10 0 0 10 10 9 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM68424.1 - 7.3e-13 48.4 66.1 0.033 14.5 1.0 9.7 9 1 0 9 9 9 8 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM68424.1 - 2.1e-05 24.7 11.5 1.4 9.2 0.1 5.6 1 1 6 7 7 7 4 BolA-like protein zf-C2H2_6 PF13912.6 KFM68424.1 - 0.0015 18.5 84.0 0.39 10.8 2.0 10.3 10 1 0 10 10 10 6 C2H2-type zinc finger DUF3396 PF11876.8 KFM68424.1 - 0.062 12.8 0.0 7.3 6.0 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3396) BHD_1 PF10403.9 KFM68424.1 - 0.094 12.6 2.1 59 3.6 0.0 4.5 5 0 0 5 5 5 0 Rad4 beta-hairpin domain 1 GAGA PF09237.11 KFM68424.1 - 0.22 11.4 0.0 0.22 11.4 0.0 6.7 2 2 5 7 7 7 0 GAGA factor zf-Di19 PF05605.12 KFM68424.1 - 0.22 11.9 67.3 0.55 10.6 9.2 6.2 2 1 3 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 KFM68424.1 - 2.3 8.2 38.6 1.9 8.5 4.8 6.1 4 2 0 4 4 4 0 Adenylate kinase, active site lid Brix PF04427.18 KFM68425.1 - 8e-32 110.9 1.3 1.2e-31 110.3 1.3 1.3 1 0 0 1 1 1 1 Brix domain dCMP_cyt_deam_1 PF00383.23 KFM68426.1 - 0.0048 16.7 2.9 0.0069 16.2 2.9 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFM68426.1 - 0.073 12.8 0.2 0.083 12.6 0.2 1.2 1 0 0 1 1 1 0 MafB19-like deaminase Bd3614-deam PF14439.6 KFM68426.1 - 0.2 11.7 0.6 0.34 11.0 0.6 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase DUF639 PF04842.12 KFM68427.1 - 0.19 11.1 3.9 0.18 11.2 1.6 1.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF639) Reticulon PF02453.17 KFM68427.1 - 0.19 11.7 6.7 0.19 11.7 5.8 1.4 1 1 1 2 2 2 0 Reticulon MRI PF15325.6 KFM68429.1 - 0.93 10.6 8.4 3.3 8.8 1.3 2.1 1 1 1 2 2 2 0 Modulator of retrovirus infection ACBP PF00887.19 KFM68430.1 - 4.6e-27 94.1 0.6 5e-27 93.9 0.6 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DDE_3 PF13358.6 KFM68431.1 - 7.1e-16 58.3 0.1 6.7e-15 55.1 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68431.1 - 3.5e-15 56.0 5.4 8.6e-15 54.7 5.4 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68431.1 - 0.00044 20.8 1.4 0.00044 20.8 1.4 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68431.1 - 0.0032 17.2 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68431.1 - 0.018 15.1 0.1 0.072 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68431.1 - 0.039 14.0 0.4 0.039 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM68432.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68432.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68433.1 - 5.3e-18 65.0 1.9 9.2e-18 64.3 1.9 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68433.1 - 7.8e-05 23.2 2.4 7.8e-05 23.2 2.4 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM68433.1 - 0.00013 22.0 0.7 0.01 15.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix MarR_2 PF12802.7 KFM68433.1 - 0.00016 21.5 0.7 0.026 14.4 0.0 2.6 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM68433.1 - 0.00093 19.1 1.1 0.0098 15.9 0.1 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM68433.1 - 0.0058 16.2 1.4 0.32 10.6 0.0 2.9 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KFM68433.1 - 0.023 14.8 1.5 1.1 9.4 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 KFM68433.1 - 0.05 14.1 0.3 5.3 7.6 0.2 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain FUR PF01475.19 KFM68433.1 - 0.078 13.1 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_23 PF13384.6 KFM68433.1 - 0.081 12.7 3.6 0.81 9.6 0.1 2.9 3 0 0 3 3 3 0 Homeodomain-like domain TrmB PF01978.19 KFM68433.1 - 0.094 12.6 0.1 3.2 7.7 0.0 2.3 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Tnp_Tc3_2 PF01498.18 KFM68434.1 - 4.1e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68434.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68434.1 - 1.9e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68434.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68434.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM68435.1 - 1.8e-10 40.7 0.0 2.1e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM68436.1 - 2.8e-28 99.2 0.2 5.9e-28 98.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM68436.1 - 1.1e-09 37.9 0.2 3.7e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM68436.1 - 0.02 13.9 3.1 0.041 12.8 0.3 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4355 PF14265.6 KFM68436.1 - 2.9 8.1 5.5 5 7.4 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Peptidase_M13 PF01431.21 KFM68437.1 - 7.7e-05 22.4 0.0 7.9e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Hydrolase_4 PF12146.8 KFM68438.1 - 2.4e-16 59.8 0.1 2.9e-11 43.1 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM68438.1 - 4.6e-11 42.9 0.1 1.9e-08 34.3 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM68438.1 - 2e-10 41.6 0.1 5.8e-10 40.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFM68438.1 - 4e-05 23.6 0.0 5.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM68438.1 - 0.00082 18.9 0.0 0.0018 17.8 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFM68438.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KFM68438.1 - 0.003 17.4 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.18 KFM68438.1 - 0.024 14.2 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KFM68438.1 - 0.028 14.0 0.1 6.2 6.3 0.0 1.9 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 KFM68438.1 - 0.032 13.9 0.0 0.049 13.3 0.0 1.4 1 1 0 1 1 1 0 PGAP1-like protein BAAT_C PF08840.11 KFM68438.1 - 0.048 13.6 0.1 0.2 11.6 0.1 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF900 PF05990.12 KFM68438.1 - 0.18 11.3 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) TMEM100 PF16311.5 KFM68440.1 - 0.033 13.8 0.6 0.075 12.6 0.6 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 Claudin_2 PF13903.6 KFM68440.1 - 0.057 13.2 1.1 0.12 12.1 0.1 1.9 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction HTH_Tnp_Tc3_2 PF01498.18 KFM68441.1 - 7.8e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68441.1 - 1.1e-15 57.6 0.1 1.3e-14 54.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM68441.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68441.1 - 0.0021 17.8 0.0 0.09 12.6 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68441.1 - 0.017 15.3 0.1 0.065 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68441.1 - 0.023 14.7 2.1 0.032 14.3 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM68441.1 - 0.093 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DDE_3 PF13358.6 KFM68442.1 - 0.0004 20.2 0.0 0.00067 19.4 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM68443.1 - 7.7e-16 58.2 0.1 7.4e-15 55.0 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68443.1 - 9.5e-16 57.8 6.5 1.8e-15 57.0 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68443.1 - 0.00086 19.9 1.5 0.00086 19.9 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68443.1 - 0.0021 17.8 0.0 0.079 12.8 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68443.1 - 0.015 15.4 0.1 0.055 13.6 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68443.1 - 0.028 14.4 2.1 0.037 14.0 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix PI-PLC-Y PF00387.19 KFM68445.1 - 8.7e-43 145.3 0.2 8.7e-43 145.3 0.2 3.6 3 1 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain PLC-beta_C PF08703.10 KFM68445.1 - 2.4e-11 43.9 30.7 2.4e-11 43.9 30.7 3.0 1 1 1 2 2 2 1 PLC-beta C terminal PI-PLC-X PF00388.19 KFM68445.1 - 7.5e-06 25.6 0.1 2.3e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KFM68446.1 - 5.1e-34 116.9 0.1 5.9e-34 116.7 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain HTH_Tnp_Tc3_2 PF01498.18 KFM68448.1 - 4.9e-16 58.7 3.5 6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68448.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68448.1 - 2.2e-07 30.5 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68448.1 - 0.0027 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68448.1 - 2.3 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain gag-asp_proteas PF13975.6 KFM68449.1 - 8.3e-06 26.3 0.0 3.2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM68449.1 - 0.00027 21.5 0.0 0.00046 20.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM68449.1 - 0.00044 20.5 0.0 0.0011 19.2 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-CCHC_4 PF14392.6 KFM68449.1 - 0.0062 16.2 0.4 0.013 15.2 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CHC2 PF01807.20 KFM68449.1 - 0.039 13.7 0.2 0.067 13.0 0.2 1.4 1 0 0 1 1 1 0 CHC2 zinc finger zf-CCHC PF00098.23 KFM68449.1 - 0.16 12.1 1.5 0.3 11.3 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle MRNIP PF15749.5 KFM68449.1 - 1.6 9.5 7.9 2.4 8.9 0.2 2.4 1 1 1 2 2 2 0 MRN-interacting protein DDE_3 PF13358.6 KFM68450.1 - 0.00013 21.8 0.0 0.00037 20.3 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease MFS_1 PF07690.16 KFM68451.1 - 4.3e-22 78.5 8.8 6.6e-22 77.9 8.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM68451.1 - 1.5e-21 76.8 6.1 2.4e-21 76.1 6.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KFM68451.1 - 0.00015 20.4 5.4 0.00024 19.7 5.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PX PF00787.24 KFM68451.1 - 0.031 14.3 0.1 3.5 7.6 0.0 2.2 2 0 0 2 2 2 0 PX domain DUF5313 PF17240.2 KFM68451.1 - 0.11 12.9 3.2 0.22 12.0 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5313) DUF2070 PF09843.9 KFM68451.1 - 0.85 7.8 5.9 1 7.5 5.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 KFM68452.1 - 1.8e-06 27.2 0.3 1.8e-06 27.2 0.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM68452.1 - 0.0078 15.1 0.1 0.01 14.7 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3725 PF12523.8 KFM68454.1 - 0.074 13.4 0.0 0.083 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) Sugar_tr PF00083.24 KFM68455.1 - 3.9e-25 88.6 6.2 5e-25 88.3 6.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM68455.1 - 2.5e-17 62.9 22.7 7.8e-17 61.2 18.4 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KFM68455.1 - 0.0032 16.0 1.4 0.0044 15.5 1.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NifU_N PF01592.16 KFM68456.1 - 1.2e-58 196.8 0.2 1.5e-58 196.5 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Proteasome PF00227.26 KFM68456.1 - 0.11 12.0 0.2 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Proteasome subunit HTH_Tnp_Tc3_2 PF01498.18 KFM68457.1 - 1.5e-09 38.0 0.4 2e-09 37.6 0.4 1.2 1 0 0 1 1 1 1 Transposase WD40 PF00400.32 KFM68458.1 - 1.6e-22 79.4 7.2 0.00061 20.5 0.0 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM68458.1 - 1.5e-08 34.8 0.0 2.8 8.3 0.0 5.1 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM68458.1 - 0.0044 16.4 0.1 0.23 10.7 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 KFM68458.1 - 0.023 13.4 1.8 1.5 7.3 0.2 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PSP PF04046.16 KFM68460.1 - 8e-18 64.1 1.0 7.2e-16 57.8 0.0 2.6 2 0 0 2 2 2 2 PSP mTERF PF02536.14 KFM68461.1 - 2.5e-06 26.7 3.3 0.0044 16.0 0.4 2.4 2 0 0 2 2 2 2 mTERF INPP5B_PH PF16776.5 KFM68462.1 - 9.6e-26 90.2 0.0 1.8e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain RhoGAP PF00620.27 KFM68462.1 - 3e-22 79.1 0.0 6.6e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 KFM68462.1 - 8.2e-16 58.2 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OCRL_clath_bd PF16726.5 KFM68462.1 - 0.0011 19.1 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate 5-phosphatase clathrin binding domain Motile_Sperm PF00635.26 KFM68462.1 - 0.021 14.7 0.1 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 MSP (Major sperm protein) domain PapD-like PF14874.6 KFM68462.1 - 0.095 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Flagellar-associated PapD-like MutS_IV PF05190.18 KFM68462.1 - 0.5 10.7 2.0 0.71 10.3 0.5 2.0 2 0 0 2 2 2 0 MutS family domain IV PhyH PF05721.13 KFM68463.1 - 2.6e-06 27.9 0.0 3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Exo_endo_phos_2 PF14529.6 KFM68468.1 - 1.7e-14 53.7 0.9 2.1e-14 53.4 0.9 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM68468.1 - 0.0085 15.6 0.1 0.0085 15.6 0.1 1.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family C2-set_2 PF08205.12 KFM68469.1 - 1.7e-11 44.0 0.2 2.1e-11 43.7 0.2 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFM68469.1 - 9.7e-10 38.5 0.1 1.2e-09 38.2 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM68469.1 - 5.7e-08 33.3 0.1 7.1e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM68469.1 - 8.9e-07 29.2 0.1 1.2e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM68469.1 - 0.00086 19.3 0.0 0.00099 19.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain C1-set PF07654.15 KFM68469.1 - 0.0055 17.1 0.0 0.0066 16.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM68469.1 - 0.13 12.5 0.1 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain MFS_1 PF07690.16 KFM68470.1 - 1e-40 139.8 27.9 3.9e-23 81.9 11.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KFM68470.1 - 1.6 7.6 12.6 0.061 12.3 4.7 2.2 2 0 0 2 2 2 0 PUCC protein MIT_LIKE_ACTX PF17556.2 KFM68471.1 - 0.019 15.6 12.8 0.029 15.0 12.8 1.3 1 0 0 1 1 1 0 MIT-like atracotoxin family HTH_Tnp_Tc3_2 PF01498.18 KFM68472.1 - 2.4e-12 46.9 6.9 6e-12 45.6 6.9 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68472.1 - 0.0018 18.9 1.3 0.0018 18.9 1.3 2.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_12 PF08461.10 KFM68472.1 - 0.0058 16.5 0.6 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain HTH_38 PF13936.6 KFM68472.1 - 0.055 13.2 0.2 0.055 13.2 0.2 2.6 3 1 0 3 3 3 0 Helix-turn-helix domain bZIP_2 PF07716.15 KFM68473.1 - 1.2e-08 34.9 17.8 1.2e-08 34.9 17.8 2.8 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM68473.1 - 3.8e-07 30.1 19.5 3.8e-07 30.1 19.5 2.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KFM68473.1 - 0.00012 22.6 11.3 0.00012 22.6 11.3 2.1 1 1 1 2 2 2 1 bZIP Maf transcription factor CASP_C PF08172.12 KFM68473.1 - 0.0087 15.4 4.9 0.013 14.9 4.9 1.4 1 0 0 1 1 1 1 CASP C terminal LCD1 PF09798.9 KFM68473.1 - 0.02 13.5 7.4 0.022 13.3 7.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein AAA_23 PF13476.6 KFM68473.1 - 0.89 10.0 7.5 1.3 9.4 7.5 1.3 1 0 0 1 1 1 0 AAA domain YabA PF06156.13 KFM68473.1 - 2.5 8.8 13.9 0.55 10.9 9.1 2.0 1 1 1 2 2 2 0 Initiation control protein YabA TSC22 PF01166.18 KFM68473.1 - 3.6 8.0 12.9 4.5 7.7 0.6 3.3 1 1 2 3 3 3 0 TSC-22/dip/bun family DHR10 PF18595.1 KFM68474.1 - 0.0019 18.2 20.3 0.0019 18.2 20.3 5.2 2 1 2 5 5 5 1 Designed helical repeat protein 10 domain DUF1759 PF03564.15 KFM68474.1 - 0.0048 16.9 3.5 0.0048 16.9 3.5 4.5 2 2 2 4 4 4 1 Protein of unknown function (DUF1759) Vac_Fusion PF02346.16 KFM68474.1 - 0.07 12.8 0.3 0.07 12.8 0.3 5.3 4 1 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Dak2 PF02734.17 KFM68474.1 - 0.3 11.0 3.7 0.19 11.6 0.6 2.2 2 0 0 2 2 2 0 DAK2 domain Mce4_CUP1 PF11887.8 KFM68474.1 - 3.4 7.1 7.5 1.5 8.2 1.0 2.3 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Borealin PF10512.9 KFM68475.1 - 5.3e-12 45.8 0.5 1.7e-11 44.1 0.5 2.0 1 1 0 1 1 1 1 Cell division cycle-associated protein 8 Nbl1_Borealin_N PF10444.9 KFM68475.1 - 0.00068 19.2 0.2 0.0016 18.0 0.2 1.7 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Phasin PF05597.11 KFM68475.1 - 0.026 14.5 0.9 0.22 11.5 0.0 2.4 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Cyclin_N PF00134.23 KFM68476.1 - 2.1e-21 76.0 0.2 3e-21 75.5 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFM68476.1 - 0.0019 18.2 0.4 0.023 14.8 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain MFS_1 PF07690.16 KFM68477.1 - 1.5e-32 113.0 33.1 1.7e-22 79.8 18.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 KFM68478.1 - 5.1e-44 148.0 1.1 5.9e-16 58.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 KFM68478.1 - 1.2e-29 102.1 0.1 3.5e-29 100.5 0.0 1.8 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 KFM68478.1 - 3.5e-07 30.3 0.3 0.018 15.1 0.0 4.0 2 2 1 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 KFM68478.1 - 7.9e-07 28.7 0.0 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFM68478.1 - 0.0011 19.0 0.3 0.84 9.7 0.0 3.2 2 2 0 2 2 2 2 Limkain b1 RRM_occluded PF16842.5 KFM68478.1 - 0.0037 17.1 0.0 0.99 9.3 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KFM68478.1 - 0.0077 16.3 0.4 0.061 13.4 0.3 2.2 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFM68478.1 - 0.021 14.8 0.3 4.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFM68478.1 - 0.048 13.9 1.6 16 5.7 0.3 3.4 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter tRNA-synt_1 PF00133.22 KFM68479.1 - 3.8e-41 141.0 0.1 1.4e-27 96.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFM68479.1 - 6.4e-18 64.7 0.0 7.1e-09 34.9 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFM68479.1 - 2.1e-17 63.5 1.0 5e-17 62.3 1.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFM68479.1 - 3.9e-07 29.7 0.0 7.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain YxiJ PF14176.6 KFM68479.1 - 0.045 14.2 0.2 14 6.2 0.0 3.1 2 0 0 2 2 2 0 YxiJ-like protein OST-HTH PF12872.7 KFM68480.1 - 9.2e-18 63.8 0.2 6.5e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 OST-HTH/LOTUS domain TUDOR PF00567.24 KFM68481.1 - 6.9e-22 77.8 0.9 2.4e-21 76.0 0.0 2.3 3 0 0 3 3 3 1 Tudor domain OST-HTH PF12872.7 KFM68481.1 - 4.9e-11 42.3 0.2 0.0003 20.5 0.0 2.7 2 0 0 2 2 2 2 OST-HTH/LOTUS domain SMN PF06003.12 KFM68481.1 - 0.0019 17.5 0.0 0.0044 16.3 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) LBR_tudor PF09465.10 KFM68481.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain KGK PF08872.10 KFM68481.1 - 0.11 13.0 0.0 1.8 9.1 0.0 2.8 2 1 1 3 3 3 0 KGK domain ABC_tran_CTD PF16326.5 KFM68482.1 - 0.023 15.0 0.9 2.9 8.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain EzrA PF06160.12 KFM68482.1 - 0.044 12.0 0.6 0.06 11.5 0.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Transp_Tc5_C PF04236.15 KFM68482.1 - 0.085 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Tropomyosin PF00261.20 KFM68483.1 - 0.0035 16.7 7.2 0.0036 16.7 7.2 1.0 1 0 0 1 1 1 1 Tropomyosin Phage-scaffold PF09306.10 KFM68483.1 - 0.063 12.6 2.0 0.062 12.6 2.0 1.0 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein ADIP PF11559.8 KFM68483.1 - 0.066 13.3 8.4 0.067 13.3 8.4 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Aconitase PF00330.20 KFM68484.1 - 2.7e-147 491.5 0.0 3.4e-147 491.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFM68484.1 - 3.6e-11 43.5 0.0 6.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KFM68484.1 - 0.083 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) DDE_3 PF13358.6 KFM68488.1 - 1.4e-08 34.6 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Hydant_A_N PF05378.13 KFM68488.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region TyeA PF09059.10 KFM68488.1 - 0.028 14.5 1.2 2.9 8.1 0.6 2.7 3 0 0 3 3 3 0 TyeA RRM_1 PF00076.22 KFM68489.1 - 2.9e-19 68.7 0.0 3.7e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM68489.1 - 4.4e-06 26.3 0.0 5.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM68489.1 - 0.00014 21.9 0.0 0.00042 20.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KFM68489.1 - 0.00045 20.0 0.0 0.0006 19.6 0.0 1.1 1 0 0 1 1 1 1 Occluded RNA-recognition motif SET_assoc PF11767.8 KFM68489.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 KFM68489.1 - 0.055 13.5 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif HTH_48 PF17906.1 KFM68491.1 - 2.6e-06 27.5 0.2 6e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM68491.1 - 0.00017 22.2 0.0 0.001 19.6 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 KFM68491.1 - 0.0029 17.1 0.7 0.064 12.8 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_9 PF08221.11 KFM68491.1 - 0.0078 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF3375 PF11855.8 KFM68491.1 - 0.16 10.8 0.1 0.46 9.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) DDE_3 PF13358.6 KFM68492.1 - 4.5e-05 23.2 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GTP_cyclohydroI PF01227.22 KFM68493.1 - 5e-76 254.1 0.1 6.2e-76 253.8 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KFM68493.1 - 0.002 18.2 0.0 0.0053 16.9 0.0 1.7 1 0 0 1 1 1 1 QueF-like protein RVT_1 PF00078.27 KFM68494.1 - 3.4e-07 30.0 0.0 3.8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) P_proprotein PF01483.20 KFM68495.1 - 7e-26 90.1 0.3 1.9e-25 88.7 0.1 1.8 2 0 0 2 2 2 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 KFM68495.1 - 1.1e-23 84.0 0.4 1.5e-23 83.5 0.4 1.2 1 0 0 1 1 1 1 Subtilase family O-FucT PF10250.9 KFM68496.1 - 1.9e-82 277.7 0.0 2.3e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase zf-H2C2_2 PF13465.6 KFM68497.1 - 4.3e-67 219.8 81.3 8.4e-08 32.3 0.3 11.4 12 0 0 12 12 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68497.1 - 2.5e-48 159.9 108.9 1e-05 25.7 0.9 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68497.1 - 2.5e-38 127.4 99.3 0.0011 19.6 2.7 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM68497.1 - 9.5e-24 83.0 91.1 0.0004 20.7 0.9 11.3 11 0 0 11 11 11 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM68497.1 - 9e-22 76.6 61.7 0.00043 20.2 2.8 11.6 11 0 0 11 11 11 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM68497.1 - 4.5e-15 55.1 67.7 0.014 15.1 1.4 11.4 11 0 0 11 11 11 7 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM68497.1 - 2.3e-13 50.1 65.6 0.045 14.1 0.1 11.4 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM68497.1 - 2e-05 24.5 41.5 1.5 8.8 3.2 7.8 3 1 3 6 6 6 3 Adenylate kinase, active site lid BolA PF01722.18 KFM68497.1 - 4.7e-05 23.6 18.9 0.75 10.1 0.5 6.9 1 1 5 7 7 7 2 BolA-like protein zf-C2HC_2 PF13913.6 KFM68497.1 - 0.00083 19.2 47.4 1.1 9.2 0.2 10.7 11 0 0 11 11 11 3 zinc-finger of a C2HC-type GAGA PF09237.11 KFM68497.1 - 0.0089 15.8 36.1 1.8 8.4 0.1 8.0 2 2 6 8 8 8 4 GAGA factor TRAF6_Z2 PF18048.1 KFM68497.1 - 0.014 15.4 51.0 3.2 7.9 0.5 10.5 11 0 0 11 11 11 0 TNF receptor-associated factor 6 zinc finger 2 Plus-3 PF03126.18 KFM68497.1 - 0.048 14.2 0.4 11 6.6 0.1 3.1 2 1 0 2 2 2 0 Plus-3 domain zf-RRPl_C4 PF17026.5 KFM68497.1 - 0.057 13.5 44.3 0.19 11.9 6.1 5.0 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-CHCC PF10276.9 KFM68497.1 - 0.074 13.1 14.5 53 4.0 0.0 8.2 11 0 0 11 11 11 0 Zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM68497.1 - 0.077 13.1 43.4 9.3 6.4 0.2 10.2 7 3 4 11 11 11 0 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM68497.1 - 0.31 10.9 57.1 8.5 6.3 1.2 10.6 5 3 6 11 11 11 0 C2H2 type zinc-finger (1 copy) PqqA PF08042.11 KFM68497.1 - 0.35 11.0 0.9 5e+02 1.0 0.0 4.9 6 0 0 6 6 6 0 PqqA family FYVE PF01363.21 KFM68497.1 - 1.2 9.4 62.6 1.6 8.9 9.2 5.7 2 2 3 5 5 5 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM68497.1 - 8.4 7.2 42.0 1.9 9.3 1.6 5.7 1 1 4 6 6 5 0 zinc-ribbon family zf-H2C2_2 PF13465.6 KFM68498.1 - 8.6e-56 184.0 51.2 1.3e-07 31.7 0.2 9.1 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68498.1 - 1e-29 101.3 76.6 0.00018 21.8 1.4 9.1 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68498.1 - 3.1e-26 89.8 73.7 0.0009 19.9 1.1 9.0 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM68498.1 - 2e-20 72.2 36.0 0.0026 17.5 0.0 8.5 8 0 0 8 8 8 7 C2H2-type zinc-finger domain zf-met PF12874.7 KFM68498.1 - 2.7e-08 33.9 73.2 0.1 13.0 0.8 9.3 9 0 0 9 9 9 6 Zinc-finger of C2H2 type ADK_lid PF05191.14 KFM68498.1 - 0.00037 20.4 27.3 1.7 8.7 1.8 6.0 5 1 1 6 6 6 3 Adenylate kinase, active site lid TRAF6_Z2 PF18048.1 KFM68498.1 - 0.00042 20.3 39.4 1.5 9.0 0.4 8.0 7 1 0 8 8 8 3 TNF receptor-associated factor 6 zinc finger 2 BolA PF01722.18 KFM68498.1 - 0.00061 20.0 11.6 1.9 8.8 0.3 5.6 1 1 4 5 5 5 1 BolA-like protein zf-C2H2_6 PF13912.6 KFM68498.1 - 0.0022 18.0 55.6 0.27 11.3 0.3 9.5 9 0 0 9 9 9 4 C2H2-type zinc finger GAGA PF09237.11 KFM68498.1 - 0.0038 17.0 30.3 0.27 11.1 0.3 7.0 2 2 5 7 7 7 4 GAGA factor zf-C2H2_9 PF16293.5 KFM68498.1 - 0.0041 16.9 41.4 3 7.8 0.7 7.8 1 1 7 8 8 8 4 C2H2 type zinc-finger (1 copy) PqqA PF08042.11 KFM68498.1 - 0.021 14.9 3.0 3.3e+02 1.5 0.0 6.1 7 0 0 7 7 7 0 PqqA family zf-CHCC PF10276.9 KFM68498.1 - 0.024 14.7 12.1 33 4.7 0.0 7.6 9 0 0 9 9 9 0 Zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM68498.1 - 0.03 14.4 28.5 33 4.7 0.4 8.7 7 1 2 9 9 9 0 Sec23/Sec24 zinc finger DUF960 PF06124.11 KFM68498.1 - 0.062 14.0 1.1 15 6.3 0.0 3.6 2 2 2 4 4 4 0 Staphylococcal protein of unknown function (DUF960) FYVE PF01363.21 KFM68498.1 - 0.19 11.9 55.0 0.25 11.5 10.7 5.1 1 1 3 4 4 4 0 FYVE zinc finger zf-FPG_IleRS PF06827.14 KFM68498.1 - 0.97 9.4 30.9 12 5.8 0.2 8.6 9 0 0 9 9 9 0 Zinc finger found in FPG and IleRS zf-RRPl_C4 PF17026.5 KFM68498.1 - 4.6 7.4 41.8 18 5.5 12.9 4.1 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type MADF_DNA_bdg PF10545.9 KFM68500.1 - 1.2e-05 25.5 0.1 1.8e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DAP3 PF10236.9 KFM68500.1 - 0.06 12.5 0.1 0.077 12.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 zf-H2C2_2 PF13465.6 KFM68501.1 - 1.4e-45 151.7 49.6 3e-08 33.7 0.6 10.1 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68501.1 - 1.2e-33 113.7 67.8 4e-06 27.0 3.0 9.3 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68501.1 - 1e-30 103.7 62.9 0.00065 20.3 2.4 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM68501.1 - 4.9e-16 58.6 47.2 0.01 16.1 1.0 9.3 7 2 2 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM68501.1 - 2.8e-15 55.9 50.7 0.0084 16.1 0.3 9.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf-met PF12874.7 KFM68501.1 - 2.2e-10 40.6 53.3 0.015 15.7 2.1 9.5 9 1 0 9 9 9 4 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 KFM68501.1 - 0.00015 22.4 30.7 0.19 12.5 0.6 4.4 2 2 1 4 4 4 3 zinc-ribbon family zf_UBZ PF18439.1 KFM68501.1 - 0.0017 17.9 35.0 0.24 11.0 0.3 8.5 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KFM68501.1 - 0.0038 17.0 21.7 15 5.5 0.1 7.4 4 2 4 8 8 8 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFM68501.1 - 0.01 16.2 44.0 0.41 11.0 11.2 7.9 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.6 KFM68501.1 - 0.016 15.1 28.9 1.7 8.6 1.0 7.6 5 4 1 6 6 6 0 HNH endonuclease zf_Hakai PF18408.1 KFM68501.1 - 0.026 14.2 2.1 0.026 14.2 2.1 5.7 6 1 0 6 6 5 0 C2H2 Hakai zinc finger domain DUF2256 PF10013.9 KFM68501.1 - 0.034 14.2 29.6 20 5.4 0.1 8.6 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_9 PF14369.6 KFM68501.1 - 0.042 14.1 22.6 2.7 8.3 0.0 7.2 8 1 1 9 9 7 0 zinc-ribbon zf-C2HC_2 PF13913.6 KFM68501.1 - 0.046 13.6 38.0 0.77 9.7 0.1 8.1 9 0 0 9 9 8 0 zinc-finger of a C2HC-type zf_C2H2_13 PF18508.1 KFM68501.1 - 0.049 13.2 7.8 0.93 9.1 0.2 4.6 4 0 0 4 4 4 0 Zinc finger domain RNA_pol_Rpb2_2 PF04561.14 KFM68501.1 - 0.085 12.5 0.2 16 5.1 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 2 TRAF6_Z2 PF18048.1 KFM68501.1 - 0.13 12.4 7.8 0.66 10.1 0.3 4.4 5 0 0 5 5 4 0 TNF receptor-associated factor 6 zinc finger 2 Yop-YscD_ppl PF16693.5 KFM68501.1 - 0.16 11.4 0.0 15 4.9 0.0 2.1 2 0 0 2 2 2 0 Inner membrane component of T3SS, periplasmic domain Vps36-NZF-N PF16988.5 KFM68501.1 - 0.2 11.1 0.0 0.2 11.1 0.0 4.2 4 1 1 5 5 5 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_11 PF16622.5 KFM68501.1 - 0.6 9.9 0.1 0.54 10.1 0.3 7.3 7 0 0 7 7 7 0 zinc-finger C2H2-type Rpr2 PF04032.16 KFM68501.1 - 0.6 10.4 32.8 1.5 9.2 0.9 5.9 2 1 1 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RRPl_C4 PF17026.5 KFM68501.1 - 0.73 10.0 30.4 0.13 12.4 2.6 3.8 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type ADK_lid PF05191.14 KFM68501.1 - 0.78 9.8 22.7 2.1 8.4 1.4 5.4 2 2 5 7 7 7 0 Adenylate kinase, active site lid HypA PF01155.19 KFM68501.1 - 1.7 8.7 24.5 0.22 11.6 2.0 4.5 1 1 2 3 3 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KFM68501.1 - 2.1 8.5 26.5 0.15 12.2 0.7 5.5 3 2 4 7 7 6 0 Zinc ribbon domain zf-BED PF02892.15 KFM68501.1 - 2.6 8.1 49.6 0.12 12.5 1.4 8.3 3 2 5 8 8 7 0 BED zinc finger DUF3268 PF11672.8 KFM68501.1 - 9.4 6.6 23.5 5.3 7.4 0.5 4.7 2 1 2 5 5 5 0 zinc-finger-containing domain DDE_Tnp_IS1595 PF12762.7 KFM68502.1 - 5.4e-09 36.2 0.0 8.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KFM68502.1 - 0.00024 20.7 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family zf-HIT PF04438.16 KFM68502.1 - 0.02 14.8 0.2 0.073 13.0 0.2 2.0 1 0 0 1 1 1 0 HIT zinc finger zf-TFIIB PF13453.6 KFM68502.1 - 0.056 12.8 0.4 0.23 10.8 0.2 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-CCHC_4 PF14392.6 KFM68503.1 - 0.029 14.1 14.0 0.18 11.5 2.1 2.9 3 0 0 3 3 3 0 Zinc knuckle HARE-HTH PF05066.13 KFM68504.1 - 7.7e-10 39.0 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain ASXH PF13919.6 KFM68504.1 - 0.0079 16.2 0.0 0.026 14.6 0.0 1.9 1 0 0 1 1 1 1 Asx homology domain Mit_KHE1 PF10173.9 KFM68504.1 - 0.15 12.2 1.9 0.15 12.1 0.5 1.7 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Dimer_Tnp_hAT PF05699.14 KFM68505.1 - 1.5e-06 27.8 0.0 5.2e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4371 PF14291.6 KFM68505.1 - 3.5e-06 26.8 0.0 3.5e-06 26.8 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4371) Methyltransf_10 PF05971.12 KFM68505.1 - 0.021 14.2 0.5 0.25 10.6 0.1 2.2 2 0 0 2 2 2 0 RNA methyltransferase HTH_Tnp_Tc3_2 PF01498.18 KFM68506.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68506.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68506.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68506.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68506.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68507.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68507.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM68508.1 - 4.2e-16 59.0 0.1 3e-15 56.2 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68508.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase RHD_DNA_bind PF00554.22 KFM68510.1 - 9.1e-28 97.3 0.7 1.1e-27 97.1 0.7 1.1 1 0 0 1 1 1 1 Rel homology DNA-binding domain WDCP PF15390.6 KFM68510.1 - 0.04 12.3 0.3 0.046 12.1 0.3 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family P-mevalo_kinase PF04275.14 KFM68510.1 - 0.44 10.5 2.9 1.2 9.1 0.3 2.1 1 1 1 2 2 2 0 Phosphomevalonate kinase RVT_1 PF00078.27 KFM68512.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.7 KFM68513.1 - 6.8e-25 87.5 5.8 2e-12 47.5 0.2 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM68513.1 - 3.4e-23 79.2 1.2 0.0017 18.6 0.0 6.4 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KFM68513.1 - 5.5e-23 80.3 0.5 0.00029 21.1 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KFM68513.1 - 3.6e-21 75.0 0.7 3e-05 24.2 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM68513.1 - 9.1e-21 74.0 9.4 6.7e-07 29.7 0.0 4.9 1 1 5 6 6 6 5 Ankyrin repeats (many copies) NLRC4_HD PF17889.1 KFM68513.1 - 0.011 16.1 2.8 0.049 14.0 1.2 2.4 2 1 0 2 2 2 0 NLRC4 helical domain DDE_3 PF13358.6 KFM68514.1 - 6.3e-07 29.3 0.0 9.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 KFM68514.1 - 0.0002 21.3 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CdvA PF18822.1 KFM68515.1 - 0.011 15.6 1.9 0.013 15.3 1.9 1.2 1 0 0 1 1 1 0 CdvA-like coiled-coil domain DUF883 PF05957.13 KFM68515.1 - 0.083 13.5 0.9 0.085 13.5 0.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF1451 PF07295.11 KFM68515.1 - 0.12 12.4 2.5 0.12 12.4 2.5 1.0 1 0 0 1 1 1 0 Zinc-ribbon containing domain YtxH PF12732.7 KFM68515.1 - 0.9 10.1 5.3 1.3 9.7 5.3 1.4 1 1 0 1 1 1 0 YtxH-like protein Death PF00531.22 KFM68516.1 - 0.024 14.8 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 Death domain DUF5626 PF18540.1 KFM68517.1 - 0.25 11.9 5.4 0.13 12.8 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5626) FAD-oxidase_C PF02913.19 KFM68518.1 - 0.035 13.7 0.2 0.064 12.9 0.2 1.6 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain Imm70 PF15601.6 KFM68518.1 - 0.045 13.3 0.2 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 Immunity protein 70 RhoGAP PF00620.27 KFM68522.1 - 2e-22 79.7 0.0 3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Synaptobrevin PF00957.21 KFM68523.1 - 3.1e-12 46.1 1.7 3.5e-12 45.9 1.7 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF4736 PF15883.5 KFM68523.1 - 0.022 14.5 0.2 0.024 14.3 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) MCD_N PF17408.2 KFM68523.1 - 0.1 12.7 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM68524.1 - 1.3e-16 60.6 2.2 4.4e-16 58.9 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68524.1 - 6e-14 52.0 0.0 9.8e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM68527.1 - 1.6e-08 34.4 0.0 3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68528.1 - 2.2e-16 59.9 2.2 6.4e-16 58.4 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68528.1 - 1.5e-13 50.7 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68528.1 - 3.4e-07 29.9 1.6 7.8e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68528.1 - 0.0031 17.2 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68528.1 - 3.2 8.4 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain CBM_14 PF01607.24 KFM68529.1 - 3.3e-09 36.8 8.6 5.8e-09 36.0 8.6 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain ANAPC3 PF12895.7 KFM68530.1 - 4.7e-27 94.0 21.1 1e-20 73.7 2.4 5.7 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFM68530.1 - 3.7e-24 82.8 23.9 0.0025 17.8 0.1 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFM68530.1 - 8e-22 76.1 18.9 1.4e-05 24.7 0.2 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFM68530.1 - 1.4e-21 74.8 16.2 0.006 16.7 0.0 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFM68530.1 - 1.9e-15 56.9 19.9 1.8e-07 31.4 0.4 8.2 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFM68530.1 - 2.9e-12 45.7 12.4 6.3e-06 25.9 0.0 6.0 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFM68530.1 - 1.2e-11 44.0 5.6 0.002 18.0 0.1 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM68530.1 - 3.4e-09 37.1 5.6 0.063 13.8 0.0 6.0 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM68530.1 - 4.2e-09 36.9 7.9 0.41 11.3 0.1 5.3 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFM68530.1 - 2.3e-07 30.7 2.3 0.45 11.0 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM68530.1 - 1.2e-06 28.8 12.3 4 8.5 0.0 8.8 7 4 3 10 10 10 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM68530.1 - 1.3e-06 28.5 1.7 0.074 13.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM68530.1 - 7e-06 25.6 1.3 0.4 10.4 0.0 6.2 6 2 2 8 8 8 1 TPR repeat TPR_15 PF13429.6 KFM68530.1 - 4.8e-05 22.7 2.2 1.4 8.1 0.0 5.0 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM68530.1 - 8.7e-05 22.9 12.7 3.2 8.6 0.1 7.7 8 1 1 9 9 9 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFM68530.1 - 0.00063 19.7 7.3 0.0013 18.8 1.0 3.6 3 1 1 4 4 4 1 Putative TPR-like repeat MIT PF04212.18 KFM68530.1 - 0.0049 16.9 8.3 31 4.7 0.0 6.4 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain Foie-gras_1 PF11817.8 KFM68530.1 - 0.028 14.0 0.5 0.28 10.7 0.0 2.6 2 1 1 3 3 3 0 Foie gras liver health family 1 ANAPC8 PF04049.13 KFM68530.1 - 0.046 13.8 0.9 0.23 11.5 0.9 2.3 1 1 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 AAR2 PF05282.11 KFM68531.1 - 1.6e-100 337.0 0.3 1.8e-100 336.8 0.3 1.0 1 0 0 1 1 1 1 AAR2 protein ASC PF00858.24 KFM68532.1 - 5.3e-44 150.9 9.9 6e-44 150.7 9.9 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 KFM68533.1 - 7.3e-08 31.8 0.9 7.3e-08 31.8 0.9 1.4 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel SNARE PF05739.19 KFM68533.1 - 0.29 11.1 0.4 0.29 11.1 0.4 1.6 2 0 0 2 2 2 0 SNARE domain GCK PF07802.11 KFM68534.1 - 0.19 12.2 0.0 0.2 12.1 0.0 1.1 1 0 0 1 1 1 0 GCK domain ALAD PF00490.21 KFM68535.1 - 1.9e-113 378.9 0.0 2.2e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase FlpD PF02662.16 KFM68535.1 - 0.12 12.3 0.0 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit adh_short PF00106.25 KFM68535.1 - 0.13 11.7 1.2 15 4.9 0.0 3.0 2 1 1 3 3 3 0 short chain dehydrogenase Ion_trans PF00520.31 KFM68536.1 - 1e-12 47.9 0.1 1.2e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 Ion transport protein ENTH PF01417.20 KFM68537.1 - 3.2e-43 146.7 0.0 5.3e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFM68537.1 - 3.5e-05 22.9 0.0 5.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 ANTH domain TAF4 PF05236.14 KFM68537.1 - 0.0018 18.1 0.3 0.0045 16.8 0.3 1.6 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family NNMT_PNMT_TEMT PF01234.17 KFM68538.1 - 5.9e-20 71.5 0.0 6.5e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Phosphorylase PF00343.20 KFM68539.1 - 5.3e-62 210.1 2.7 5.9e-62 210.0 2.7 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Phosphorylase PF00343.20 KFM68540.1 - 4e-246 818.8 0.0 4.7e-246 818.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase V-ATPase_C PF03223.15 KFM68542.1 - 7.1e-158 525.8 4.8 8e-158 525.7 4.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Cep57_MT_bd PF06657.13 KFM68542.1 - 0.076 13.5 1.3 0.18 12.3 0.1 2.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 FliD_N PF02465.18 KFM68542.1 - 0.17 12.6 1.2 0.36 11.6 0.3 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Mod_r PF07200.13 KFM68542.1 - 2.8 8.0 8.5 0.96 9.5 4.8 2.1 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MyTH4 PF00784.17 KFM68543.1 - 9.8e-32 109.7 6.8 5e-29 101.0 5.6 3.4 2 1 0 2 2 2 1 MyTH4 domain FERM_M PF00373.18 KFM68543.1 - 4.1e-15 56.2 0.0 7.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFM68543.1 - 0.043 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 FERM N-terminal domain PH PF00169.29 KFM68544.1 - 0.0043 17.5 0.0 0.0044 17.5 0.0 1.1 1 0 0 1 1 1 1 PH domain PH PF00169.29 KFM68545.1 - 4.2e-18 65.8 0.5 1.1e-16 61.2 0.1 2.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFM68545.1 - 2.4e-07 31.1 3.8 2.4e-07 31.1 3.8 4.4 2 2 1 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 KFM68545.1 - 1e-06 28.9 1.0 8.5e-06 26.0 0.2 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFM68545.1 - 8.4e-05 22.6 2.7 0.0001 22.3 0.1 2.4 2 0 0 2 2 2 1 PH domain AAA-ATPase_like PF09820.9 KFM68545.1 - 0.002 17.6 0.6 0.002 17.6 0.6 2.4 2 0 0 2 2 2 1 Predicted AAA-ATPase DUF3584 PF12128.8 KFM68545.1 - 0.57 7.6 30.5 0.78 7.2 30.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-H PF05837.12 KFM68545.1 - 4.4 7.8 34.0 0.044 14.2 7.4 4.1 4 1 0 4 4 4 0 Centromere protein H (CENP-H) PPDK_N PF01326.19 KFM68546.1 - 1.4e-64 218.4 0.2 1.8e-64 218.1 0.2 1.1 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM68547.1 - 4.2e-16 58.9 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68547.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68547.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68547.1 - 0.0027 17.4 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68547.1 - 0.03 14.5 0.4 0.086 13.0 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM68547.1 - 2.3 8.9 15.1 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68548.1 - 2e-16 60.0 2.2 4.2e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68548.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68549.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68549.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.32 KFM68551.1 - 8.8e-23 80.2 3.3 6.2e-10 39.5 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Utp12 PF04003.12 KFM68551.1 - 3.6e-15 56.2 0.1 1.9e-14 53.8 0.1 2.0 1 1 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFM68551.1 - 5.6e-06 26.6 0.1 0.0073 16.6 0.1 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM68551.1 - 6.1e-06 26.2 0.1 9.3e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFM68551.1 - 0.00055 19.0 0.0 0.028 13.4 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein YccV-like PF08755.11 KFM68554.1 - 0.028 14.9 7.7 0.27 11.7 0.3 4.0 3 0 0 3 3 3 0 Hemimethylated DNA-binding protein YccV like BolA PF01722.18 KFM68554.1 - 1.8 8.9 6.7 0.8 10.0 0.0 3.8 4 0 0 4 4 4 0 BolA-like protein AT_hook PF02178.19 KFM68554.1 - 3.7 7.7 7.2 11 6.3 7.2 1.8 1 0 0 1 1 1 0 AT hook motif HTH_Tnp_Tc3_2 PF01498.18 KFM68555.1 - 2e-16 60.0 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68555.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease LIM PF00412.22 KFM68556.1 - 5.7e-30 103.3 23.5 5e-16 58.7 8.3 2.2 2 0 0 2 2 2 2 LIM domain PHD_4 PF16866.5 KFM68556.1 - 0.037 14.1 1.4 0.037 14.1 1.4 2.5 2 0 0 2 2 2 0 PHD-finger zf_UBZ PF18439.1 KFM68556.1 - 0.38 10.4 0.0 0.38 10.4 0.0 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger SR1P PF13790.6 KFM68556.1 - 1.2 9.3 0.0 1.2 9.3 0.0 4.0 4 0 0 4 4 4 0 SR1 protein Oxysterol_BP PF01237.18 KFM68558.1 - 6.3e-115 384.0 1.1 3.2e-114 381.7 1.1 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein HTH_Tnp_Tc3_2 PF01498.18 KFM68559.1 - 7.4e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68559.1 - 3.8e-15 55.9 0.1 4.5e-14 52.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM68559.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68560.1 - 5e-16 58.7 2.2 5e-16 58.7 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68560.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ax_dynein_light PF10211.9 KFM68561.1 - 3.7e-43 147.6 3.3 4.9e-43 147.3 3.3 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain BaffR-Tall_bind PF09256.10 KFM68561.1 - 0.014 15.1 1.8 0.041 13.6 1.8 1.8 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding PXA PF02194.15 KFM68561.1 - 0.025 14.6 0.6 0.42 10.6 0.3 2.1 2 0 0 2 2 2 0 PXA domain CHASE3 PF05227.13 KFM68561.1 - 0.032 14.1 1.1 0.062 13.2 1.1 1.4 1 0 0 1 1 1 0 CHASE3 domain Rootletin PF15035.6 KFM68561.1 - 0.05 13.6 3.3 0.098 12.7 1.8 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Ig_3 PF13927.6 KFM68563.1 - 7.2e-09 36.1 0.0 8.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM68563.1 - 2.2e-07 30.8 0.0 0.00094 19.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM68563.1 - 4.2e-06 26.8 0.0 0.0059 16.8 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM68563.1 - 9.8e-05 22.4 0.0 0.00025 21.0 0.0 1.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM68563.1 - 0.049 13.8 0.0 0.6 10.3 0.0 2.3 3 0 0 3 3 3 0 Immunoglobulin V-set domain BORCS7 PF16088.5 KFM68564.1 - 0.016 15.5 0.6 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 tRNA_NucTran2_2 PF13735.6 KFM68564.1 - 0.036 14.0 0.1 0.069 13.1 0.1 1.4 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Conotoxin PF02950.17 KFM68565.1 - 1.1 10.3 6.4 4.8 8.3 6.4 1.9 1 1 0 1 1 1 0 Conotoxin Toxin_7 PF05980.12 KFM68565.1 - 2.9 8.2 9.1 0.38 11.0 4.9 1.8 2 0 0 2 2 2 0 Toxin 7 HTH_Tnp_Tc3_2 PF01498.18 KFM68566.1 - 3.2e-14 52.9 1.0 6.2e-14 52.0 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68566.1 - 8.6e-14 51.5 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease BTB PF00651.31 KFM68567.1 - 1e-20 74.0 2.5 1.3e-11 44.6 0.1 4.5 2 2 2 4 4 4 3 BTB/POZ domain BACK PF07707.15 KFM68567.1 - 2e-07 31.1 3.1 1.4e-06 28.3 1.8 2.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFM68568.1 - 1.3e-16 60.8 0.3 2.6e-14 53.4 0.0 3.2 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFM68568.1 - 5.5e-09 36.0 0.3 1.4e-08 34.8 0.3 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF576 PF04507.12 KFM68568.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Csa1 family Antigen_Bd37 PF11641.8 KFM68569.1 - 0.078 12.5 0.0 0.078 12.5 0.0 1.0 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein HHH PF00633.23 KFM68570.1 - 0.042 13.7 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Glyco_hydro_31 PF01055.26 KFM68571.1 - 8.8e-83 278.9 0.7 1.1e-82 278.5 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFM68571.1 - 6.3e-24 84.4 0.3 1.4e-23 83.2 0.3 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFM68571.1 - 8.3e-13 48.5 0.1 4.3e-12 46.2 0.2 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Trefoil PF00088.18 KFM68571.1 - 2e-11 43.6 4.6 3.6e-11 42.7 4.6 1.5 1 0 0 1 1 1 1 Trefoil (P-type) domain DUF5110 PF17137.4 KFM68572.1 - 2.8e-08 33.9 1.7 4.5e-08 33.2 1.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5110) Glyco_hydro_31 PF01055.26 KFM68573.1 - 3.3e-83 280.3 1.1 3.7e-83 280.1 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_66 PF13199.6 KFM68573.1 - 0.029 13.0 0.5 0.043 12.5 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 FAM195 PF14799.6 KFM68574.1 - 2.4e-27 95.3 4.0 3.5e-27 94.7 4.0 1.2 1 0 0 1 1 1 1 FAM195 family DUF632 PF04782.12 KFM68574.1 - 0.007 15.7 0.0 0.0076 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF632) Myb_DNA-bind_4 PF13837.6 KFM68575.1 - 1.4e-06 28.5 1.9 9.1e-06 26.0 0.1 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF1476 PF07345.11 KFM68575.1 - 0.024 15.0 0.1 0.078 13.4 0.1 1.8 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Myb_DNA-bind_3 PF12776.7 KFM68575.1 - 0.11 13.5 0.1 0.11 13.5 0.1 2.3 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3287 PF11690.8 KFM68575.1 - 0.33 10.7 3.8 8.1 6.2 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) FlaC_arch PF05377.11 KFM68575.1 - 0.88 10.0 5.7 2.9 8.3 0.4 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DASH_Hsk3 PF08227.11 KFM68575.1 - 1 9.8 4.3 33 5.0 0.0 3.3 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF1664 PF07889.12 KFM68575.1 - 4.7 7.3 6.8 6.8 6.8 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ldl_recept_a PF00057.18 KFM68576.1 - 0.0033 17.6 14.9 0.0044 17.2 5.9 2.4 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A ADAM_spacer1 PF05986.14 KFM68578.1 - 1.3e-25 89.6 0.0 1.8e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Antifungal_pept PF11410.8 KFM68578.1 - 0.041 13.8 1.7 0.041 13.8 1.7 1.9 2 0 0 2 2 2 0 Antifungal peptide DAGK_cat PF00781.24 KFM68578.1 - 0.045 13.4 0.1 0.075 12.7 0.1 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain RRM_1 PF00076.22 KFM68579.1 - 6.9e-18 64.2 0.0 1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM68579.1 - 0.0057 16.5 0.0 0.0076 16.1 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-C4 PF00105.18 KFM68580.1 - 1.6e-16 60.5 5.1 1.9e-16 60.2 5.1 1.1 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) HTH_Tnp_Tc3_2 PF01498.18 KFM68581.1 - 4.7e-16 58.8 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68581.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68581.1 - 1.9e-07 30.7 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68581.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68581.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF1681 PF07933.14 KFM68582.1 - 2.5e-19 69.5 0.0 2.6e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Imm75 PF15660.6 KFM68582.1 - 0.055 13.7 0.1 0.061 13.6 0.1 1.2 1 0 0 1 1 1 0 Putative Immunity protein 75 PARG_cat PF05028.14 KFM68583.1 - 1.4e-07 31.2 0.0 3.6e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Poly (ADP-ribose) glycohydrolase (PARG) CBM_14 PF01607.24 KFM68584.1 - 6.9e-39 131.8 44.4 5.6e-10 39.2 6.1 5.4 5 0 0 5 5 5 5 Chitin binding Peritrophin-A domain NLPC_P60 PF00877.19 KFM68584.1 - 0.31 11.1 2.0 6.8 6.8 0.2 2.5 2 0 0 2 2 2 0 NlpC/P60 family ArenaCapSnatch PF17296.2 KFM68585.1 - 0.18 11.2 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain ArenaCapSnatch PF17296.2 KFM68586.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain DDE_3 PF13358.6 KFM68587.1 - 3.5e-13 49.5 0.0 6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68587.1 - 1.3e-10 41.4 1.0 2e-10 40.8 1.0 1.3 1 0 0 1 1 1 1 Transposase RXT2_N PF08595.11 KFM68587.1 - 0.19 11.7 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CUT PF02376.15 KFM68588.1 - 9.7e-80 262.8 0.3 1.2e-26 92.7 0.0 3.6 3 0 0 3 3 3 3 CUT domain Homeodomain PF00046.29 KFM68588.1 - 7.4e-17 60.9 0.2 1.9e-16 59.6 0.2 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM68588.1 - 6.6e-07 29.1 0.0 2.1e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Mit_KHE1 PF10173.9 KFM68588.1 - 0.58 10.2 3.4 1.7 8.7 3.4 1.8 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF2347 PF09804.9 KFM68588.1 - 6.7 6.2 6.3 0.52 9.9 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF1640 PF07798.11 KFM68589.1 - 4.7e-07 30.0 4.5 6.7e-07 29.5 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Apolipoprotein PF01442.18 KFM68589.1 - 5.5e-06 26.4 6.0 1.1e-05 25.5 6.0 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM68589.1 - 1.3e-05 25.3 0.1 0.00074 19.6 0.0 2.0 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Focal_AT PF03623.13 KFM68589.1 - 0.00045 20.2 3.8 0.00067 19.6 3.5 1.4 1 1 0 1 1 1 1 Focal adhesion targeting region Golgin_A5 PF09787.9 KFM68589.1 - 0.00047 19.7 8.7 0.00065 19.3 8.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 SF-assemblin PF06705.11 KFM68589.1 - 0.00052 19.4 7.4 0.00073 19.0 7.4 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin Fib_alpha PF08702.10 KFM68589.1 - 0.00061 20.0 3.3 0.00061 20.0 3.3 1.6 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family CCDC154 PF15450.6 KFM68589.1 - 0.00068 18.3 6.7 0.00082 18.0 6.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 DUF1664 PF07889.12 KFM68589.1 - 0.001 19.1 10.3 0.0051 16.8 9.9 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFM68589.1 - 0.0025 18.2 12.0 0.051 14.0 0.1 4.0 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) Spore_III_AB PF09548.10 KFM68589.1 - 0.0025 18.0 1.7 0.0036 17.4 1.7 1.2 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Mer2 PF09074.10 KFM68589.1 - 0.01 15.6 5.1 0.015 15.1 5.1 1.2 1 0 0 1 1 1 0 Mer2 Prominin PF05478.11 KFM68589.1 - 0.01 13.8 3.6 0.012 13.6 3.6 1.1 1 0 0 1 1 1 0 Prominin DUF148 PF02520.17 KFM68589.1 - 0.032 14.4 7.4 0.074 13.2 5.4 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF1451 PF07295.11 KFM68589.1 - 0.035 14.1 2.5 0.052 13.6 2.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain COG2 PF06148.11 KFM68589.1 - 0.057 13.5 11.3 0.81 9.8 0.7 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ApoLp-III PF07464.11 KFM68589.1 - 0.075 13.1 11.2 0.46 10.6 11.6 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ApoO PF09769.9 KFM68589.1 - 0.11 12.5 0.9 1.1 9.2 0.8 2.4 1 1 2 3 3 3 0 Apolipoprotein O Spc7 PF08317.11 KFM68589.1 - 0.12 11.2 9.5 0.22 10.4 9.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KFM68589.1 - 0.13 12.8 6.9 25 5.4 7.0 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Z1 PF10593.9 KFM68589.1 - 0.14 11.7 2.7 0.18 11.3 2.7 1.2 1 0 0 1 1 1 0 Z1 domain DUF883 PF05957.13 KFM68589.1 - 0.21 12.2 5.4 0.18 12.4 3.3 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4795 PF16043.5 KFM68589.1 - 0.21 11.1 8.4 0.67 9.5 7.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) ABC_tran_CTD PF16326.5 KFM68589.1 - 0.28 11.5 6.3 0.87 9.9 0.0 3.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain CdvA PF18822.1 KFM68589.1 - 0.33 10.8 10.1 3.6 7.4 7.9 2.8 1 1 2 3 3 3 0 CdvA-like coiled-coil domain DUF4164 PF13747.6 KFM68589.1 - 0.33 11.2 5.5 2.6 8.4 5.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TipAS PF07739.13 KFM68589.1 - 0.4 11.2 5.2 0.56 10.8 4.7 1.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain CCDC-167 PF15188.6 KFM68589.1 - 0.42 11.0 8.3 5 7.5 0.1 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 WXG100 PF06013.12 KFM68589.1 - 0.43 10.9 7.0 1.4 9.2 3.9 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG TMPIT PF07851.13 KFM68589.1 - 0.53 9.5 5.0 0.74 9.0 5.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein BCAS2 PF05700.11 KFM68589.1 - 0.58 9.8 6.4 1.1 8.9 6.0 1.6 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) FIN1 PF17300.2 KFM68589.1 - 0.61 9.6 6.0 0.89 9.0 6.0 1.2 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 DUF4140 PF13600.6 KFM68589.1 - 0.62 10.5 5.7 14 6.2 5.8 2.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) COMP PF11598.8 KFM68589.1 - 0.67 10.5 4.9 22 5.6 0.0 3.8 2 1 2 4 4 4 0 Cartilage oligomeric matrix protein Phasin PF05597.11 KFM68589.1 - 0.73 9.8 10.8 4.5 7.3 10.7 2.2 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fzo_mitofusin PF04799.13 KFM68589.1 - 1.2 8.7 7.1 5 6.6 6.6 1.9 1 1 1 2 2 2 0 fzo-like conserved region zf-CCHC_6 PF15288.6 KFM68590.1 - 3.7e-09 36.3 7.7 2.2e-05 24.2 1.0 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 KFM68590.1 - 3.3e-06 26.9 13.5 2.4e-05 24.2 2.3 3.5 3 0 0 3 3 3 2 Zinc knuckle zf-ribbon_3 PF13248.6 KFM68590.1 - 0.0081 15.5 7.5 0.33 10.4 0.4 3.5 3 0 0 3 3 3 2 zinc-ribbon domain zf-CCHC_2 PF13696.6 KFM68590.1 - 0.03 14.2 1.6 0.091 12.6 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFM68590.1 - 0.19 11.5 4.8 1.9 8.3 0.6 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-FCS PF06467.14 KFM68590.1 - 0.84 9.6 9.6 6.3 6.8 1.3 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HscB_4_cys PF18256.1 KFM68590.1 - 1.8 8.4 17.3 2 8.3 3.0 3.0 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif MLVIN_C PF18697.1 KFM68591.1 - 0.0038 17.3 0.1 0.0051 16.9 0.1 1.3 1 1 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF4904 PF16247.5 KFM68591.1 - 0.2 11.5 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) SlyX PF04102.12 KFM68592.1 - 0.0056 17.3 3.4 0.0067 17.0 3.4 1.2 1 0 0 1 1 1 1 SlyX DUF1493 PF07377.12 KFM68592.1 - 0.05 14.1 0.6 0.33 11.4 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) Pkinase PF00069.25 KFM68593.1 - 1e-29 103.7 0.0 1.1e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM68593.1 - 9.4e-11 41.5 0.0 1e-10 41.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM68593.1 - 1.2e-05 25.3 0.0 1.5e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM68593.1 - 9e-05 21.9 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFM68593.1 - 0.0014 18.3 0.1 0.0016 18.0 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFM68593.1 - 0.0018 17.9 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 KFM68593.1 - 0.023 14.2 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.6 KFM68593.1 - 0.026 13.9 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KFM68594.1 - 0.0022 17.4 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Frizzled PF01534.17 KFM68595.1 - 5.3e-37 127.6 6.3 5.3e-37 127.6 6.3 1.6 2 0 0 2 2 2 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFM68595.1 - 1.2e-12 48.4 1.4 2.3e-12 47.5 1.4 1.4 1 0 0 1 1 1 1 Fz domain UPF0220 PF05255.11 KFM68595.1 - 0.14 11.7 8.1 0.69 9.4 7.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0220) Oxidored_q3 PF00499.20 KFM68595.1 - 0.22 11.2 7.8 0.25 11.1 0.4 2.9 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Saf_2TM PF18303.1 KFM68595.1 - 1.9 8.1 5.3 1.5 8.4 2.5 2.3 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain DUF202 PF02656.15 KFM68595.1 - 4.4 7.8 10.1 12 6.4 0.0 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF202) Frizzled PF01534.17 KFM68596.1 - 3.5e-17 62.5 2.0 3.8e-17 62.3 2.0 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_1 PF00001.21 KFM68598.1 - 1.9e-10 40.5 4.7 2.5e-10 40.1 4.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1494 PF07379.11 KFM68598.1 - 0.061 13.2 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) HTH_Tnp_Tc3_2 PF01498.18 KFM68599.1 - 2.2e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68599.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease tRNA-synt_1c PF00749.21 KFM68600.1 - 1e-111 372.8 0.0 2.1e-111 371.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KFM68600.1 - 1.8e-50 171.1 5.5 1.8e-50 171.1 5.5 2.2 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KFM68600.1 - 7.8e-29 100.8 1.3 2.5e-28 99.1 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KFM68600.1 - 8.8e-26 90.7 5.0 2.4e-25 89.2 5.0 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF2102 PF09875.9 KFM68600.1 - 0.021 14.5 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) DDE_Tnp_1_7 PF13843.6 KFM68601.1 - 2.5e-35 122.4 0.0 3e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM68601.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.4 1 1 0 1 1 1 0 Transposase DDE domain DUF1758 PF05585.12 KFM68604.1 - 1.9e-10 40.8 0.1 2.7e-10 40.3 0.1 1.3 1 1 0 1 1 1 1 Putative peptidase (DUF1758) Peptidase_A17 PF05380.13 KFM68605.1 - 2.8e-06 27.4 0.1 3.3e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Pao retrotransposon peptidase Mre11_DNA_bind PF04152.14 KFM68606.1 - 0.05 13.9 0.2 0.058 13.7 0.2 1.0 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain SAND PF01342.21 KFM68606.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 SAND domain Exo_endo_phos_2 PF14529.6 KFM68610.1 - 3e-17 62.6 0.0 3.7e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM68610.1 - 4.8e-05 23.0 0.1 6.5e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ADAM_spacer1 PF05986.14 KFM68613.1 - 2e-23 82.6 0.0 3.9e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Ion_trans PF00520.31 KFM68614.1 - 2.7e-179 593.4 73.8 3.9e-70 235.9 15.7 3.1 3 0 0 3 3 3 3 Ion transport protein Na_trans_cytopl PF11933.8 KFM68614.1 - 2.5e-34 118.9 4.2 3.3e-33 115.3 4.2 2.3 1 1 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.13 KFM68614.1 - 3.2e-19 70.0 5.1 3.2e-19 70.0 5.1 2.6 3 0 0 3 3 3 1 Sodium ion transport-associated PKD_channel PF08016.12 KFM68614.1 - 9.1e-18 64.1 62.4 1.3e-05 24.1 2.2 8.0 5 2 2 7 7 7 7 Polycystin cation channel GPHH PF16905.5 KFM68614.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 KFM68614.1 - 0.009 15.5 0.0 0.032 13.8 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFM68614.1 - 0.12 12.8 1.2 23 5.5 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair RVT_1 PF00078.27 KFM68616.1 - 4.3e-10 39.5 0.1 9.7e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_6 PF15288.6 KFM68616.1 - 0.00012 21.8 0.6 0.00027 20.7 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KFM68616.1 - 0.0024 17.8 0.3 0.0064 16.5 0.3 1.8 1 0 0 1 1 1 1 Zinc knuckle RuvB_C PF05491.13 KFM68616.1 - 0.049 13.5 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 RuvB C-terminal winged helix domain Mu-like_Com PF10122.9 KFM68616.1 - 0.19 11.2 0.1 0.19 11.2 0.1 1.9 2 0 0 2 2 2 0 Mu-like prophage protein Com RT_RNaseH_2 PF17919.1 KFM68617.1 - 1e-30 105.7 0.0 2.8e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM68617.1 - 3e-29 102.1 1.3 4e-29 101.7 0.3 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM68617.1 - 2e-27 95.5 0.1 1.2e-26 93.0 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM68617.1 - 3.3e-18 65.5 0.0 8.8e-18 64.2 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM68617.1 - 6.6e-17 61.8 0.0 2.2e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFM68617.1 - 2.5e-06 27.6 0.4 6.1e-06 26.3 0.4 1.7 1 0 0 1 1 1 1 H2C2 zinc finger BH4 PF02180.17 KFM68617.1 - 0.038 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Bcl-2 homology region 4 DDE_Tnp_IS240 PF13610.6 KFM68617.1 - 0.093 13.0 2.0 0.14 12.4 0.2 2.2 2 0 0 2 2 2 0 DDE domain CRAL_TRIO PF00650.20 KFM68619.1 - 3.6e-30 104.8 0.1 5.4e-30 104.2 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM68619.1 - 2.3e-11 44.3 0.1 1.9e-05 25.2 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 KFM68619.1 - 4.2e-05 23.6 0.6 0.00012 22.2 0.2 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM68619.1 - 0.0076 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain C1q PF00386.21 KFM68619.1 - 0.016 15.4 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 C1q domain CRAL_TRIO PF00650.20 KFM68620.1 - 1.2e-28 99.8 0.1 2.5e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM68620.1 - 1.5e-09 38.4 0.3 0.00029 21.3 0.0 2.5 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 KFM68620.1 - 7.5e-05 22.8 0.1 0.00025 21.1 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM68620.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM68621.1 - 1.9e-28 99.2 0.0 3e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM68621.1 - 2.4e-12 47.5 0.4 1.2e-06 29.1 0.1 2.4 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 KFM68621.1 - 1.8e-05 24.8 0.1 5.1e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1759 PF03564.15 KFM68622.1 - 1.7e-18 66.9 0.1 1.6e-17 63.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) rve PF00665.26 KFM68622.1 - 6e-12 45.8 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KFM68622.1 - 3e-09 36.7 2.4 2.6e-08 33.6 0.0 3.2 3 1 1 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 KFM68622.1 - 3.6e-05 23.5 0.0 7.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 KFM68622.1 - 4.6e-05 24.0 0.0 0.00013 22.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM68622.1 - 6.3e-05 23.5 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 KFM68622.1 - 0.00046 20.0 0.1 0.00099 18.9 0.1 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Peptidase_A17 PF05380.13 KFM68622.1 - 0.00053 20.0 0.2 0.0019 18.3 0.0 2.1 2 0 0 2 2 2 1 Pao retrotransposon peptidase ATG11 PF10377.9 KFM68622.1 - 0.008 16.2 0.3 0.018 15.1 0.3 1.5 1 0 0 1 1 1 1 Autophagy-related protein 11 RVP PF00077.20 KFM68622.1 - 0.065 13.6 0.1 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease NDUF_B5 PF09781.9 KFM68623.1 - 0.014 15.0 0.4 0.021 14.4 0.4 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit CRAL_TRIO PF00650.20 KFM68626.1 - 9.1e-31 106.7 0.0 1.6e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM68626.1 - 6.8e-11 42.8 0.8 7.4e-06 26.5 0.2 2.8 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 KFM68626.1 - 8.2e-05 22.7 0.8 0.00022 21.3 0.8 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM68626.1 - 0.028 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain TSC22 PF01166.18 KFM68627.1 - 0.00073 19.8 0.9 0.00094 19.4 0.9 1.2 1 0 0 1 1 1 1 TSC-22/dip/bun family K-box PF01486.17 KFM68627.1 - 0.0011 19.0 1.7 0.0016 18.6 1.7 1.3 1 0 0 1 1 1 1 K-box region bZIP_1 PF00170.21 KFM68627.1 - 0.0038 17.3 1.9 0.0048 17.0 1.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor Syntaxin-6_N PF09177.11 KFM68627.1 - 0.017 15.7 0.7 0.019 15.5 0.7 1.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal GIT_CC PF16559.5 KFM68627.1 - 0.026 14.4 1.2 0.036 13.9 1.2 1.2 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 KFM68627.1 - 0.028 14.5 3.7 0.059 13.5 3.7 1.7 1 1 0 1 1 1 0 Basic region leucine zipper HflK_N PF12221.8 KFM68627.1 - 0.029 14.4 0.4 0.037 14.0 0.4 1.2 1 0 0 1 1 1 0 Bacterial membrane protein N terminal FlaC_arch PF05377.11 KFM68627.1 - 0.11 12.9 1.5 0.14 12.6 1.5 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 KFM68628.1 - 0.21 11.7 12.1 0.24 11.5 12.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPD52 PF04201.15 KFM68628.1 - 0.8 9.3 5.3 0.9 9.1 5.3 1.1 1 0 0 1 1 1 0 Tumour protein D52 family HOOK PF05622.12 KFM68629.1 - 0.024 12.8 38.6 0.03 12.5 38.6 1.1 1 0 0 1 1 1 0 HOOK protein bZIP_1 PF00170.21 KFM68629.1 - 0.042 13.9 0.6 0.042 13.9 0.6 5.7 6 1 0 6 6 6 0 bZIP transcription factor TSC22 PF01166.18 KFM68629.1 - 0.14 12.5 0.1 0.14 12.5 0.1 5.0 3 1 0 4 4 4 0 TSC-22/dip/bun family bZIP_2 PF07716.15 KFM68629.1 - 0.15 12.2 0.4 0.15 12.2 0.4 6.0 7 0 0 7 7 7 0 Basic region leucine zipper T3SS_needle_F PF09392.10 KFM68629.1 - 0.26 11.5 10.1 4.3 7.6 0.3 4.5 5 0 0 5 5 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF TolA_bind_tri PF16331.5 KFM68629.1 - 1.2 9.3 21.2 1.5 9.0 0.2 4.8 3 1 1 4 4 4 0 TolA binding protein trimerisation DUF4239 PF14023.6 KFM68629.1 - 2.3 7.9 6.3 1.7 8.4 1.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) Fib_alpha PF08702.10 KFM68629.1 - 4.9 7.3 31.0 1.5 9.0 11.4 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KFM68629.1 - 5.4 7.1 47.1 1.8 8.7 21.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TraF_2 PF13729.6 KFM68629.1 - 6.2 6.1 7.4 0.97 8.7 1.4 2.2 1 1 0 2 2 2 0 F plasmid transfer operon, TraF, protein DASH_Dam1 PF08653.10 KFM68629.1 - 6.8 6.6 12.5 16 5.4 0.2 4.4 4 0 0 4 4 4 0 DASH complex subunit Dam1 C2 PF00168.30 KFM68630.1 - 1e-06 29.0 0.0 1.3e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 C2 domain C2-C2_1 PF11618.8 KFM68630.1 - 2.9e-05 24.2 0.0 3.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 First C2 domain of RPGR-interacting protein 1 RPGR1_C PF18111.1 KFM68632.1 - 2.9e-08 33.8 0.0 3e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Retinitis pigmentosa G-protein regulator interacting C-terminal RPGR1_C PF18111.1 KFM68633.1 - 2.1e-10 40.7 0.0 2.3e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 Retinitis pigmentosa G-protein regulator interacting C-terminal RVT_1 PF00078.27 KFM68634.1 - 1.5e-09 37.7 0.1 2.3e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFM68635.1 - 0.0025 17.4 0.2 0.0039 16.7 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) FTO_CTD PF12934.7 KFM68636.1 - 0.0035 17.1 2.8 0.0045 16.8 2.4 1.3 1 1 0 1 1 1 1 FTO C-terminal domain mRNA_cap_C PF03919.15 KFM68636.1 - 0.012 16.2 6.3 0.033 14.8 6.3 1.7 1 1 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Equine_IAV_S2 PF06502.11 KFM68636.1 - 0.23 11.5 2.4 0.43 10.7 2.4 1.4 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein PRE_C2HC PF07530.11 KFM68637.1 - 1.4e-08 34.7 0.4 3e-08 33.6 0.4 1.5 1 0 0 1 1 1 1 Associated with zinc fingers JTB PF05439.12 KFM68637.1 - 4.3 7.4 10.5 7.7 6.6 4.9 2.3 1 1 1 2 2 2 0 Jumping translocation breakpoint protein (JTB) AAA_2 PF07724.14 KFM68638.1 - 3.6e-38 131.3 0.0 7.8e-38 130.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 KFM68638.1 - 1.3e-14 54.0 0.1 3.2e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KFM68638.1 - 6.4e-14 52.5 0.0 1.4e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM68638.1 - 2.6e-05 24.0 0.0 0.00022 21.0 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KFM68638.1 - 2.7e-05 24.2 0.0 7.8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFM68638.1 - 8.1e-05 22.1 0.1 0.02 14.3 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFM68638.1 - 0.00013 21.6 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFM68638.1 - 0.00068 19.9 0.1 0.0028 17.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFM68638.1 - 0.0012 18.6 0.1 0.0039 17.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KFM68638.1 - 0.0023 17.7 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KFM68638.1 - 0.0037 17.6 0.0 0.0088 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KFM68638.1 - 0.0051 15.9 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 KFM68638.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFM68638.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFM68638.1 - 0.016 15.2 0.0 0.044 13.7 0.0 1.8 2 0 0 2 2 1 0 NACHT domain AAA_29 PF13555.6 KFM68638.1 - 0.019 14.7 0.1 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KFM68638.1 - 0.023 15.0 0.2 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KFM68638.1 - 0.029 14.5 0.0 0.093 12.9 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain TIP49 PF06068.13 KFM68638.1 - 0.033 13.4 0.0 0.072 12.3 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KFM68638.1 - 0.042 13.6 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM68638.1 - 0.046 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.29 KFM68638.1 - 0.066 13.0 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase MCM PF00493.23 KFM68638.1 - 0.084 11.9 0.1 0.24 10.4 0.1 1.7 2 0 0 2 2 2 0 MCM P-loop domain AAA_25 PF13481.6 KFM68638.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain zinc_ribbon_4 PF13717.6 KFM68638.1 - 0.16 11.9 7.0 2.3 8.2 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain TackOD1 PF18551.1 KFM68638.1 - 0.18 11.5 3.8 0.069 12.8 1.0 1.6 2 0 0 2 2 1 0 Thaumarchaeal output domain 1 Zn_Tnp_IS1595 PF12760.7 KFM68638.1 - 0.73 9.9 3.9 1.6 8.7 3.9 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.6 KFM68638.1 - 3.5 7.4 6.1 9.3 6.1 6.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain HTH_Tnp_Tc3_2 PF01498.18 KFM68639.1 - 6.9e-16 58.3 6.5 1.7e-15 57.0 6.5 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68639.1 - 1.9e-15 56.9 0.1 2.2e-14 53.5 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM68639.1 - 0.00082 19.9 1.5 0.00082 19.9 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68639.1 - 0.003 17.3 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68639.1 - 0.016 15.3 0.1 0.073 13.2 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68639.1 - 0.04 14.0 0.4 0.04 14.0 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix DUF3082 PF11282.8 KFM68641.1 - 0.045 14.0 1.2 0.23 11.7 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3082) Translin PF01997.16 KFM68644.1 - 7.9e-53 179.5 0.7 1.1e-52 179.0 0.7 1.2 1 0 0 1 1 1 1 Translin family YhdB PF14148.6 KFM68644.1 - 0.33 11.1 3.3 2.1 8.5 0.9 2.6 2 0 0 2 2 2 0 YhdB-like protein Argos PF11581.8 KFM68645.1 - 7.9e-56 187.6 9.0 7.9e-56 187.6 9.0 1.7 2 0 0 2 2 2 1 Antagonist of EGFR signalling, Argos PapD_N PF00345.20 KFM68645.1 - 0.17 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Terminase_GpA PF05876.12 KFM68645.1 - 0.35 9.4 2.3 0.18 10.3 0.2 1.4 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) DUF2733 PF10813.8 KFM68646.1 - 0.48 10.3 1.9 15 5.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2733) GTP_EFTU_D2 PF03144.25 KFM68647.1 - 7.3e-11 42.3 0.0 2.7e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFM68647.1 - 5.2e-08 32.9 0.1 2.3e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.18 KFM68647.1 - 0.015 15.1 0.0 0.25 11.1 0.0 2.7 3 0 0 3 3 3 0 Elongation factor G, domain IV GTP_EFTU PF00009.27 KFM68650.1 - 1.5e-29 102.9 0.0 1.7e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM68650.1 - 0.022 14.8 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KFM68650.1 - 0.037 13.5 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFM68650.1 - 0.067 13.1 0.1 0.12 12.3 0.0 1.5 1 1 1 2 2 2 0 RsgA GTPase DUF5110 PF17137.4 KFM68652.1 - 0.038 14.3 0.3 0.066 13.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Glyco_hydro_31 PF01055.26 KFM68653.1 - 2.4e-41 142.3 0.1 2.9e-41 142.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF1736 PF08409.11 KFM68655.1 - 2.4e-32 110.8 0.9 2.4e-32 110.8 0.9 1.8 2 0 0 2 2 1 1 Domain of unknown function (DUF1736) TPR_1 PF00515.28 KFM68655.1 - 1.4e-29 100.7 8.9 1.8e-09 37.0 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFM68655.1 - 8e-25 84.9 4.2 1.2e-07 31.3 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFM68655.1 - 3.5e-24 82.9 9.4 9.9e-07 28.5 0.4 6.0 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM68655.1 - 4e-22 77.6 15.5 2.5e-13 49.5 0.4 6.5 4 2 3 7 7 6 5 TPR repeat TPR_17 PF13431.6 KFM68655.1 - 2.2e-18 65.2 11.7 1.4e-06 28.3 0.1 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFM68655.1 - 1.5e-17 63.6 5.1 0.00034 20.8 0.0 4.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM68655.1 - 7.7e-17 61.7 2.4 3.5e-11 43.6 0.0 3.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM68655.1 - 4.6e-15 54.5 2.0 0.0084 16.1 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM68655.1 - 1.5e-13 51.1 19.1 2.3e-08 34.4 0.8 4.1 1 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFM68655.1 - 1.5e-12 47.2 3.4 0.0095 16.7 0.0 5.7 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFM68655.1 - 1.7e-12 46.8 6.4 0.0044 16.9 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM68655.1 - 2.9e-08 33.8 0.8 0.0028 17.8 0.0 2.6 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFM68655.1 - 6.3e-07 29.5 0.1 0.0005 20.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM68655.1 - 1.2e-05 25.7 7.5 0.32 11.7 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat NARP1 PF12569.8 KFM68655.1 - 4.8e-05 22.5 3.9 0.0059 15.6 1.6 2.7 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 Rapsyn_N PF10579.9 KFM68655.1 - 0.00034 20.7 0.1 0.0031 17.6 0.0 2.5 3 0 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.14 KFM68655.1 - 0.00076 19.9 0.0 0.29 11.9 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KFM68655.1 - 0.001 18.6 0.3 0.013 14.9 0.3 2.1 1 1 1 2 2 2 2 Coatomer epsilon subunit TPR_21 PF09976.9 KFM68655.1 - 0.0024 17.6 0.1 0.055 13.2 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain SNAP PF14938.6 KFM68655.1 - 0.0085 15.5 0.8 0.13 11.7 0.1 2.3 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 KFM68655.1 - 0.017 15.2 0.0 0.059 13.4 0.0 2.0 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFM68655.1 - 0.026 14.5 1.4 4 7.4 0.2 2.5 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 PTPS_related PF10131.9 KFM68655.1 - 0.034 12.5 7.6 0.054 11.8 7.6 1.2 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein FAT PF02259.23 KFM68655.1 - 0.12 11.5 0.3 20 4.2 0.0 2.6 1 1 1 3 3 3 0 FAT domain Pex24p PF06398.11 KFM68655.1 - 5.1 6.0 5.0 23 3.8 1.4 2.8 2 1 0 3 3 3 0 Integral peroxisomal membrane peroxin TMEM252 PF15664.5 KFM68657.1 - 0.036 13.8 2.1 6.8 6.4 0.1 3.0 3 0 0 3 3 3 0 Transmembrane protein 252 family TctA PF01970.16 KFM68658.1 - 0.11 11.2 0.2 0.14 10.8 0.2 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Gal-3-0_sulfotr PF06990.11 KFM68659.1 - 9.1e-31 107.1 1.6 1.2e-30 106.8 1.6 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 KFM68659.1 - 0.00067 19.6 0.5 0.0012 18.9 0.5 1.3 1 0 0 1 1 1 1 Sulfotransferase family WRW PF10206.9 KFM68659.1 - 0.09 13.2 1.7 4.7 7.6 0.9 2.3 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f zf-H2C2_2 PF13465.6 KFM68660.1 - 0.006 17.0 1.4 0.078 13.4 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double domain Zn-C2H2_12 PF18112.1 KFM68660.1 - 0.022 15.2 1.6 4.9 7.7 0.7 3.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-met PF12874.7 KFM68660.1 - 0.036 14.5 0.3 0.15 12.5 0.3 2.1 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Mtf2_C PF14061.6 KFM68660.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 zf-C2H2_4 PF13894.6 KFM68660.1 - 0.14 13.1 0.3 0.14 13.1 0.3 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM68660.1 - 0.19 12.2 10.6 3.3 8.3 0.2 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type HTH_Tnp_Tc3_2 PF01498.18 KFM68663.1 - 7.4e-16 58.2 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68663.1 - 8.5e-14 51.5 0.1 8.3e-13 48.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM68663.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68663.1 - 0.003 17.3 0.1 0.14 12.0 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68663.1 - 0.019 15.1 0.1 0.075 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68663.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM68664.1 - 0.0027 17.5 0.0 0.0034 17.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3437 PF11919.8 KFM68665.1 - 0.033 14.1 4.0 4.1 7.4 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF4149 PF13664.6 KFM68666.1 - 5.3e-23 81.3 2.8 5.3e-23 81.3 2.8 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF5134 PF17197.4 KFM68666.1 - 0.5 10.3 7.5 19 5.2 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) HMG_box PF00505.19 KFM68667.1 - 6.8e-28 96.9 3.3 1.3e-27 96.0 3.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box SOXp PF12336.8 KFM68667.1 - 5.6e-23 81.8 7.0 5.6e-23 81.8 7.0 2.8 3 1 0 3 3 3 1 SOX transcription factor HMG_box_2 PF09011.10 KFM68667.1 - 1.6e-11 44.6 2.1 3.1e-11 43.7 2.1 1.5 1 0 0 1 1 1 1 HMG-box domain DDE_3 PF13358.6 KFM68668.1 - 3.1e-11 43.2 0.0 4.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68668.1 - 4e-07 30.2 0.3 9.1e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM68669.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68669.1 - 1.6e-13 50.6 0.0 2.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68669.1 - 3.1e-07 30.0 0.7 6.3e-07 29.1 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68669.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68669.1 - 1.8 9.2 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68670.1 - 4.8e-16 58.8 3.5 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68670.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68670.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68670.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68670.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68671.1 - 5e-16 58.7 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68671.1 - 2.7e-11 43.4 0.0 4.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68671.1 - 5.8e-07 29.2 1.7 7e-07 28.9 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68671.1 - 0.0025 17.5 0.6 0.0075 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68671.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_1 PF03184.19 KFM68672.1 - 4.5e-50 169.7 0.1 8.4e-50 168.8 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM68672.1 - 2.2e-12 46.8 0.0 1.7e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM68672.1 - 0.001 18.6 0.0 0.0033 17.0 0.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Carb_anhydrase PF00194.21 KFM68673.1 - 7.5e-16 58.4 0.0 8.3e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KFM68674.1 - 1.1e-29 103.7 0.0 1.3e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase PID PF00640.23 KFM68674.1 - 0.0078 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) HTH_Tnp_Tc3_2 PF01498.18 KFM68676.1 - 2.2e-16 59.9 2.2 4.5e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68676.1 - 9.6e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM68677.1 - 0.003 17.3 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RPM2 PF08579.11 KFM68677.1 - 0.11 13.0 0.0 0.12 12.7 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) CHGN PF05679.16 KFM68678.1 - 4.7e-186 619.6 0.1 5.8e-186 619.3 0.1 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 KFM68678.1 - 1.4e-17 64.0 0.0 2.6e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 KFM68678.1 - 6.2e-11 41.8 0.0 1.8e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 KFM68678.1 - 6.2e-06 26.1 0.0 0.0024 17.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KFM68678.1 - 8.2e-05 22.2 1.0 0.28 10.6 0.0 3.5 4 0 0 4 4 4 2 Glycosyltransferase like family 2 Galactosyl_T PF01762.21 KFM68678.1 - 0.0021 17.9 0.3 0.019 14.8 0.2 2.6 2 1 0 2 2 2 1 Galactosyltransferase Glyco_tranf_2_3 PF13641.6 KFM68678.1 - 0.05 13.5 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFM68678.1 - 0.13 11.7 0.0 0.42 10.1 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 21 NNMT_PNMT_TEMT PF01234.17 KFM68679.1 - 2.9e-32 111.9 0.0 3.4e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.6 KFM68679.1 - 0.028 14.2 0.0 0.077 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF3721 PF12518.8 KFM68679.1 - 0.11 12.4 0.5 0.29 11.0 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function NNMT_PNMT_TEMT PF01234.17 KFM68680.1 - 1.6e-29 102.8 0.0 1.9e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.6 KFM68680.1 - 0.13 12.0 0.0 0.41 10.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFM68680.1 - 0.15 12.8 0.0 0.34 11.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain UCR_6-4kD PF08997.10 KFM68681.1 - 9.4e-22 76.7 0.1 1e-21 76.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.9 KFM68681.1 - 0.2 11.7 1.0 0.75 9.9 1.0 1.8 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) HTH_48 PF17906.1 KFM68682.1 - 1.4e-06 28.3 1.3 2.3e-06 27.6 1.3 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Arrestin_C PF02752.22 KFM68683.1 - 5.4e-25 88.4 0.0 8.7e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFM68683.1 - 6e-23 81.5 0.0 1.8e-21 76.7 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KFM68683.1 - 0.0093 15.2 0.2 0.049 12.8 0.1 1.9 2 0 0 2 2 2 1 Rgp1 HTH_Tnp_Tc3_2 PF01498.18 KFM68684.1 - 4.7e-16 58.8 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68684.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68684.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68684.1 - 0.0026 17.5 0.6 0.0078 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68684.1 - 0.026 14.7 0.4 0.093 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM68684.1 - 7.8 7.2 17.8 0.13 12.9 2.0 3.4 3 1 1 4 4 4 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68685.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68685.1 - 4.5e-14 52.4 0.0 7.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Filament PF00038.21 KFM68686.1 - 5.3e-76 256.2 67.4 1.7e-74 251.2 67.4 2.0 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFM68686.1 - 1.4e-14 54.4 0.3 3e-14 53.3 0.3 1.6 1 0 0 1 1 1 1 Lamin Tail Domain FPP PF05911.11 KFM68686.1 - 2.2e-07 29.5 54.9 0.00028 19.3 31.9 2.2 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 KFM68686.1 - 0.00028 19.9 20.7 0.00028 19.9 20.7 3.2 1 1 2 3 3 3 1 Spc7 kinetochore protein DUF3450 PF11932.8 KFM68686.1 - 0.00077 18.8 24.9 0.004 16.5 2.8 5.7 1 1 4 6 6 6 3 Protein of unknown function (DUF3450) ATG16 PF08614.11 KFM68686.1 - 0.0018 18.5 72.1 0.0047 17.2 32.6 4.2 1 1 4 5 5 5 2 Autophagy protein 16 (ATG16) Macoilin PF09726.9 KFM68686.1 - 0.0026 16.4 55.5 0.011 14.3 55.4 2.0 1 1 0 1 1 1 1 Macoilin family Cep57_CLD_2 PF14197.6 KFM68686.1 - 0.0091 16.1 11.1 0.0091 16.1 11.1 5.6 3 2 1 4 4 3 1 Centrosome localisation domain of PPC89 GCN5L1 PF06320.13 KFM68686.1 - 0.011 15.9 7.1 0.011 15.9 7.1 4.6 2 2 2 5 5 5 0 GCN5-like protein 1 (GCN5L1) TPR_MLP1_2 PF07926.12 KFM68686.1 - 0.039 14.0 66.7 0.051 13.6 20.6 4.6 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.19 KFM68686.1 - 0.092 10.5 67.6 0.53 8.0 67.7 1.8 1 1 1 2 2 2 0 Myosin tail Phage_min_tail PF05939.13 KFM68686.1 - 0.13 12.6 0.2 0.41 11.1 0.2 1.8 1 0 0 1 1 1 0 Phage minor tail protein GIT_CC PF16559.5 KFM68686.1 - 0.21 11.5 27.3 0.73 9.7 0.2 5.5 4 1 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 KFM68686.1 - 1.1 9.1 62.6 8.1 6.2 27.6 3.8 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH SF-assemblin PF06705.11 KFM68686.1 - 1.1 8.6 50.1 0.015 14.6 14.6 3.1 1 1 2 3 3 3 0 SF-assemblin/beta giardin MAD PF05557.13 KFM68686.1 - 1.1 7.5 64.5 4.7 5.4 30.3 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein Sugarporin_N PF11471.8 KFM68686.1 - 1.9 8.5 9.2 11 6.0 0.1 3.6 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension LPP PF04728.13 KFM68686.1 - 2 8.9 14.6 44 4.6 0.1 4.5 3 1 0 3 3 3 0 Lipoprotein leucine-zipper HALZ PF02183.18 KFM68686.1 - 2.9 8.2 38.1 0.074 13.3 3.3 6.0 6 1 1 7 7 4 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 KFM68686.1 - 2.9 7.9 62.8 19 5.3 17.2 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KFM68686.1 - 3.2 7.8 32.8 0.37 10.8 4.7 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KFM68686.1 - 3.5 7.0 60.2 1.4 8.3 23.1 3.3 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF3584 PF12128.8 KFM68686.1 - 5.3 4.4 56.0 0.78 7.2 50.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1843 PF08898.10 KFM68686.1 - 5.5 7.6 11.1 12 6.5 0.2 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) APG6_N PF17675.1 KFM68686.1 - 5.9 7.4 71.5 49 4.5 9.2 4.8 1 1 3 4 4 3 0 Apg6 coiled-coil region GAS PF13851.6 KFM68686.1 - 8.3 5.7 64.2 4.6 6.5 35.5 3.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 KFM68686.1 - 9.2 6.3 69.4 0.027 14.5 10.0 7.0 2 2 4 6 6 6 0 TATA element modulatory factor 1 DNA binding ApoO PF09769.9 KFM68686.1 - 9.3 6.2 15.0 3.7 7.5 0.7 4.2 2 1 2 4 4 4 0 Apolipoprotein O HTH_Tnp_Tc3_2 PF01498.18 KFM68691.1 - 9.2e-16 57.9 6.5 1.7e-15 57.0 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68691.1 - 1.1e-15 57.7 0.1 1.1e-14 54.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease Thyroglobulin_1 PF00086.18 KFM68691.1 - 0.00038 20.1 0.6 0.00076 19.1 0.6 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat HTH_32 PF13565.6 KFM68691.1 - 0.00084 19.9 1.5 0.00084 19.9 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68691.1 - 0.0036 17.0 0.1 0.13 12.1 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68691.1 - 0.019 15.1 0.1 0.074 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68691.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix LapA_dom PF06305.11 KFM68692.1 - 0.0034 17.2 3.6 0.098 12.5 0.6 2.1 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain IncE PF17627.2 KFM68692.1 - 0.016 15.3 2.5 0.02 14.9 2.5 1.1 1 0 0 1 1 1 0 Inclusion membrane protein E DUF4381 PF14316.6 KFM68692.1 - 0.092 13.0 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ATPase_gene1 PF09527.10 KFM68692.1 - 3.3 7.9 8.0 0.62 10.3 2.2 2.0 1 1 1 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter HTH_32 PF13565.6 KFM68694.1 - 7.4e-08 32.9 0.3 2.1e-07 31.4 0.3 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68694.1 - 0.014 15.6 0.3 0.03 14.6 0.3 1.5 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.6 KFM68694.1 - 0.024 14.6 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 KFM68694.1 - 0.034 14.3 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain SpoIIID PF12116.8 KFM68694.1 - 0.089 12.9 0.1 0.18 11.9 0.1 1.6 2 0 0 2 2 2 0 Stage III sporulation protein D DDE_1 PF03184.19 KFM68695.1 - 1.2e-09 38.0 0.7 2.6e-09 37.0 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Feld-I_B PF09252.10 KFM68695.1 - 0.044 13.7 0.1 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Allergen Fel d I-B chain NadA PF02445.16 KFM68695.1 - 0.31 10.2 3.6 0.45 9.6 0.1 2.0 1 1 1 2 2 2 0 Quinolinate synthetase A protein ABC2_membrane PF01061.24 KFM68696.1 - 1.5e-36 125.8 20.0 1.5e-36 125.8 20.0 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFM68696.1 - 1.3e-23 84.0 0.0 2.6e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM68696.1 - 6e-05 23.0 0.9 0.079 12.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM68696.1 - 0.0097 15.4 0.4 0.55 9.6 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFM68696.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM68696.1 - 0.1 12.4 0.6 0.22 11.3 0.6 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM68696.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFM68696.1 - 0.12 12.3 0.3 0.22 11.4 0.3 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 KFM68696.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KFM68696.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KFM68696.1 - 0.16 12.4 0.9 0.28 11.6 0.9 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 KFM68696.1 - 0.18 11.1 4.1 0.28 10.4 3.7 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein RRM_1 PF00076.22 KFM68698.1 - 6.7e-19 67.5 0.1 8.1e-19 67.2 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peripla_BP_4 PF13407.6 KFM68698.1 - 0.029 13.9 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain RNA_bind PF08675.11 KFM68698.1 - 0.033 14.2 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain CRAL_TRIO_2 PF13716.6 KFM68700.1 - 8.6e-05 22.7 0.1 8.6e-05 22.7 0.1 1.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM68700.1 - 0.068 12.9 0.1 0.076 12.7 0.1 1.1 1 0 0 1 1 1 0 CRAL/TRIO domain DHHA2 PF02833.14 KFM68701.1 - 7.2e-22 78.1 0.1 1.3e-21 77.3 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain BNIP2 PF12496.8 KFM68701.1 - 6.6e-18 65.5 4.5 1.8e-17 64.0 4.4 1.8 1 1 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.6 KFM68701.1 - 1.4e-09 38.2 0.2 3.2e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Cnd1 PF12717.7 KFM68701.1 - 0.011 15.8 0.3 0.025 14.6 0.3 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 ATP-synt_F PF01990.17 KFM68702.1 - 3.9e-06 27.1 0.1 4.1e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit ubiquitin PF00240.23 KFM68704.1 - 4e-10 39.3 0.1 5.8e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFM68704.1 - 0.00065 19.5 0.1 0.00092 19.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KFM68704.1 - 0.0063 16.6 0.6 0.011 15.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFM68704.1 - 0.087 13.3 0.1 0.21 12.1 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Mtp PF03821.16 KFM68705.1 - 3.6e-15 56.2 4.4 4e-07 29.9 0.1 2.5 2 1 1 3 3 3 2 Golgi 4-transmembrane spanning transporter Ni_hydr_CYTB PF01292.20 KFM68705.1 - 0.058 13.0 2.3 0.16 11.5 2.3 1.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PRIMA1 PF16101.5 KFM68705.1 - 0.16 12.0 0.1 3.5 7.7 0.3 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF4728 PF15860.5 KFM68705.1 - 0.36 11.6 10.8 2.6 8.8 5.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4728) Transposase_1 PF01359.18 KFM68706.1 - 0.0009 19.0 0.7 0.018 14.9 0.7 2.1 1 1 0 1 1 1 1 Transposase (partial DDE domain) PGAP1 PF07819.13 KFM68708.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFM68708.1 - 0.017 15.8 0.0 0.043 14.4 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family HEAT_2 PF13646.6 KFM68708.1 - 0.033 14.6 0.0 0.38 11.2 0.0 2.5 2 1 0 2 2 2 0 HEAT repeats Arm PF00514.23 KFM68708.1 - 0.084 12.9 0.2 19 5.5 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Hydrolase_4 PF12146.8 KFM68708.1 - 0.088 12.1 0.0 0.32 10.2 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ABC_membrane PF00664.23 KFM68709.1 - 4.5e-12 46.2 7.7 4.5e-12 46.2 7.7 2.3 2 1 0 2 2 2 1 ABC transporter transmembrane region DUF885 PF05960.11 KFM68711.1 - 4.6e-61 208.1 0.2 5.1e-61 207.9 0.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Poxvirus PF06227.12 KFM68711.1 - 0.052 13.3 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 dsDNA Poxvirus Laminin_EGF PF00053.24 KFM68712.1 - 5.4e-05 23.2 38.1 0.00047 20.3 12.8 3.4 2 1 1 3 3 3 2 Laminin EGF domain fn3 PF00041.21 KFM68712.1 - 0.0045 17.3 0.0 0.0096 16.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Pkinase PF00069.25 KFM68713.1 - 1e-08 34.9 0.0 1.1e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM68713.1 - 6.1e-07 29.0 0.0 8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM68714.1 - 5e-13 49.0 0.0 7.1e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM68714.1 - 1.1e-12 47.8 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Death_2 PF14786.6 KFM68714.1 - 9e-07 28.9 0.1 2.7e-06 27.3 0.1 1.8 1 1 0 1 1 1 1 Tube Death domain Death PF00531.22 KFM68714.1 - 0.0012 18.9 0.2 0.0043 17.2 0.2 2.1 1 1 0 1 1 1 1 Death domain HMG_box PF00505.19 KFM68715.1 - 1.2e-33 115.3 8.0 5e-17 62.1 0.1 3.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM68715.1 - 4.6e-26 91.2 8.2 7.2e-17 61.7 2.4 3.4 3 1 0 3 3 2 2 HMG-box domain HMG_box_5 PF14887.6 KFM68715.1 - 0.0029 17.5 5.2 0.061 13.3 0.7 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF4769 PF15992.5 KFM68715.1 - 0.0039 17.0 6.3 0.0075 16.1 6.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4769) CDC45 PF02724.14 KFM68715.1 - 0.0063 14.9 9.0 0.011 14.1 9.0 1.4 1 0 0 1 1 1 1 CDC45-like protein eIF-3_zeta PF05091.12 KFM68715.1 - 0.0092 15.0 15.6 0.013 14.6 15.6 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 KFM68715.1 - 0.15 12.0 23.8 0.3 11.0 23.8 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GREB1 PF15782.5 KFM68715.1 - 0.16 9.0 21.6 0.23 8.5 21.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5427 PF10310.9 KFM68715.1 - 0.4 9.6 20.5 0.61 9.0 20.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Plasmodium_Vir PF05795.11 KFM68715.1 - 1.3 8.3 9.0 2.5 7.4 9.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Band_3_cyto PF07565.13 KFM68715.1 - 1.5 8.6 14.6 2.9 7.6 14.6 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SAPS PF04499.15 KFM68715.1 - 1.7 7.3 12.4 2.2 7.0 12.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Gti1_Pac2 PF09729.9 KFM68715.1 - 3.2 7.8 15.2 9.1 6.3 15.2 1.9 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4407 PF14362.6 KFM68715.1 - 3.3 7.0 19.1 1.5 8.1 16.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SLC12 PF03522.15 KFM68715.1 - 5.2 6.0 18.6 7.8 5.4 18.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 KFM68715.1 - 5.3 7.0 18.2 11 6.0 18.2 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 KFM68715.1 - 5.8 5.5 19.0 8.5 4.9 19.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ALMT PF11744.8 KFM68715.1 - 5.9 5.6 12.3 9.5 4.9 12.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4551 PF15087.6 KFM68715.1 - 7.1 5.3 21.5 11 4.7 21.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) V_ATPase_I PF01496.19 KFM68715.1 - 8 4.2 15.1 11 3.8 15.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 KFM68715.1 - 8.2 5.5 9.8 1.1 8.3 5.8 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Hamartin PF04388.12 KFM68715.1 - 8.9 4.8 22.1 15 4.0 22.1 1.4 1 0 0 1 1 1 0 Hamartin protein Band_7_C PF16200.5 KFM68716.1 - 5.9e-27 93.5 1.4 1.3e-26 92.5 1.4 1.6 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7 PF01145.25 KFM68717.1 - 6.9e-14 52.2 0.1 8.2e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Reprolysin_5 PF13688.6 KFM68718.1 - 0.00052 20.2 0.1 0.0018 18.4 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 TMEM219 PF14940.6 KFM68718.1 - 0.068 12.7 0.1 0.068 12.7 0.1 1.1 1 0 0 1 1 1 0 Transmembrane 219 wnt PF00110.19 KFM68719.1 - 3.4e-15 56.5 0.1 4e-15 56.2 0.1 1.0 1 0 0 1 1 1 1 wnt family UTP15_C PF09384.10 KFM68720.1 - 0.15 11.7 2.0 0.25 11.0 1.2 1.7 1 1 1 2 2 2 0 UTP15 C terminal Tetraspanin PF00335.20 KFM68722.1 - 9.1e-30 104.1 2.3 1e-29 103.9 2.3 1.0 1 0 0 1 1 1 1 Tetraspanin family p450 PF00067.22 KFM68725.1 - 1.9e-07 30.2 0.1 2.3e-07 29.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_28 PF13518.6 KFM68726.1 - 6e-07 29.5 0.0 6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68726.1 - 1.2e-06 28.1 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 KFM68726.1 - 1.4e-06 28.3 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase MarR_2 PF12802.7 KFM68726.1 - 0.00048 20.0 0.0 0.00057 19.7 0.0 1.1 1 0 0 1 1 1 1 MarR family CENP-B_N PF04218.13 KFM68726.1 - 0.0016 18.0 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 KFM68726.1 - 0.0022 17.7 0.0 0.0029 17.3 0.0 1.1 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_38 PF13936.6 KFM68726.1 - 0.0051 16.5 0.1 0.0067 16.2 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM68726.1 - 0.0079 16.2 0.1 0.0083 16.1 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_6 PF01418.17 KFM68726.1 - 0.012 15.6 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family MarR PF01047.22 KFM68726.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 MarR family HTH_Tnp_ISL3 PF13542.6 KFM68726.1 - 0.017 14.5 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.20 KFM68726.1 - 0.021 14.7 1.0 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Tnp_4 PF13613.6 KFM68726.1 - 0.079 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_24 PF13412.6 KFM68726.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 KFM68726.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Sigma-70, region 4 zf-C2H2_4 PF13894.6 KFM68727.1 - 1.3e-06 28.7 14.6 0.0073 17.1 0.5 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM68727.1 - 4.7e-06 26.8 20.2 0.028 14.9 1.1 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KFM68727.1 - 0.0009 19.9 5.2 0.0011 19.7 2.6 2.1 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 KFM68727.1 - 0.006 16.7 5.5 3.6 7.8 0.6 3.4 2 1 1 3 3 3 1 Zic proteins zinc finger domain zinc_ribbon_4 PF13717.6 KFM68727.1 - 0.0061 16.5 12.2 0.21 11.6 0.1 3.6 4 0 0 4 4 3 1 zinc-ribbon domain DUF678 PF05077.12 KFM68727.1 - 0.011 15.8 13.6 0.039 14.1 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF678) zf-C2H2_2 PF12756.7 KFM68727.1 - 0.015 15.6 15.1 0.67 10.3 1.1 3.1 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM68727.1 - 0.02 14.5 7.8 4.3 7.0 0.1 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger TBK1_CCD1 PF18394.1 KFM68727.1 - 0.02 14.4 0.8 0.02 14.4 0.8 1.6 2 0 0 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 FYVE PF01363.21 KFM68727.1 - 0.028 14.6 13.4 2.8 8.1 2.0 3.4 3 1 0 3 3 3 0 FYVE zinc finger HypA PF01155.19 KFM68727.1 - 0.029 14.4 10.4 1.1 9.3 4.3 2.9 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_jaz PF12171.8 KFM68727.1 - 0.034 14.4 0.5 0.034 14.4 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 KFM68727.1 - 0.041 13.9 8.6 1.2 9.2 0.3 3.4 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2HE PF16278.5 KFM68727.1 - 0.05 14.1 15.0 0.78 10.2 0.5 3.3 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KFM68727.1 - 0.086 13.3 0.9 0.086 13.3 0.9 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KFM68727.1 - 0.27 11.9 6.7 0.84 10.3 0.5 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zinc_ribbon_15 PF17032.5 KFM68727.1 - 0.27 12.0 18.1 1.3 9.8 1.9 2.3 1 1 0 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM68727.1 - 0.28 11.3 9.8 19 5.5 0.3 3.7 4 0 0 4 4 3 0 Zinc ribbon domain DUF629 PF04780.12 KFM68727.1 - 0.33 9.4 12.8 1.9 6.9 1.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zinc_ribbon_5 PF13719.6 KFM68727.1 - 0.53 10.1 10.3 0.92 9.3 1.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-RanBP PF00641.18 KFM68727.1 - 1 8.7 16.4 4.9 6.6 0.2 3.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.7 KFM68727.1 - 1.4 9.0 10.1 0.5 10.4 2.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_9 PF16293.5 KFM68727.1 - 2 8.3 10.6 1.7 8.6 0.7 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Jas PF16135.5 KFM68727.1 - 2.1 8.6 8.8 0.67 10.2 0.8 2.9 2 1 1 3 3 3 0 TPL-binding domain in jasmonate signalling zf-BED PF02892.15 KFM68727.1 - 2.6 8.2 15.1 3.9 7.6 0.7 3.4 2 1 1 3 3 3 0 BED zinc finger C1_4 PF07975.12 KFM68727.1 - 2.9 8.2 16.4 1.3 9.3 0.8 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain Mut7-C PF01927.16 KFM68727.1 - 5.4 7.1 10.1 0.54 10.4 4.0 1.9 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-C2H2_4 PF13894.6 KFM68728.1 - 1.4e-11 44.2 44.8 0.0044 17.7 3.7 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM68728.1 - 6.3e-08 32.6 45.1 0.0019 18.6 4.8 6.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-MYST PF17772.1 KFM68728.1 - 0.00012 21.6 16.4 1.5 8.5 0.0 4.6 3 1 1 4 4 4 4 MYST family zinc finger domain zf-met PF12874.7 KFM68728.1 - 0.002 18.4 4.0 0.014 15.7 1.9 6.7 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KFM68728.1 - 0.0072 17.0 26.7 0.14 12.9 1.4 5.2 2 1 4 6 6 6 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KFM68728.1 - 0.097 13.0 0.1 0.097 13.0 0.1 6.3 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM68728.1 - 0.15 12.4 25.7 1 9.8 0.6 4.9 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM68729.1 - 4.6e-06 27.0 59.7 0.023 15.5 3.1 7.7 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM68729.1 - 0.019 15.3 42.5 0.35 11.2 2.3 6.5 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM68729.1 - 0.031 14.0 4.7 0.031 14.0 4.7 5.3 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM68729.1 - 0.058 13.9 58.3 0.89 10.1 0.8 7.6 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM68729.1 - 0.11 13.0 1.1 0.11 13.0 1.1 7.8 7 1 0 7 7 7 0 Zinc-finger double domain PGI PF00342.19 KFM68729.1 - 0.14 10.7 0.5 0.49 8.9 0.3 1.8 1 1 1 2 2 2 0 Phosphoglucose isomerase DUF3847 PF12958.7 KFM68729.1 - 0.24 11.5 2.3 0.74 10.0 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) MH1 PF03165.16 KFM68730.1 - 0.008 16.4 0.3 0.0089 16.2 0.3 1.0 1 0 0 1 1 1 1 MH1 domain Lipase_GDSL_2 PF13472.6 KFM68731.1 - 0.00017 22.0 0.0 0.00022 21.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFM68731.1 - 0.00023 21.2 0.0 0.00024 21.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MASE2 PF05230.11 KFM68731.1 - 0.14 12.3 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 MASE2 domain HTH_32 PF13565.6 KFM68732.1 - 0.00022 21.7 0.1 0.00037 21.0 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68732.1 - 0.00088 19.0 1.5 0.013 15.3 0.2 2.4 2 1 1 3 3 3 1 Homeodomain-like domain HTH_10 PF04967.12 KFM68732.1 - 0.0021 17.8 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 HTH DNA binding domain HTH_24 PF13412.6 KFM68732.1 - 0.0024 17.4 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding ANT PF03374.14 KFM68732.1 - 0.0026 18.0 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 Phage antirepressor protein KilAC domain HTH_17 PF12728.7 KFM68732.1 - 0.0029 17.7 0.0 0.072 13.3 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM68732.1 - 0.0058 16.1 0.1 0.0093 15.5 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 KFM68732.1 - 0.016 14.6 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_19 PF12844.7 KFM68732.1 - 0.021 14.8 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r3 PF04539.16 KFM68732.1 - 0.055 13.6 0.1 0.12 12.5 0.1 1.5 1 1 1 2 2 2 0 Sigma-70 region 3 HTH_28 PF13518.6 KFM68732.1 - 0.061 13.5 0.5 0.65 10.2 0.1 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain DUF2309 PF10070.9 KFM68732.1 - 0.071 11.4 0.0 0.085 11.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) HTH_Mga PF08280.11 KFM68732.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain MarR_2 PF12802.7 KFM68732.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 1 0 2 2 2 0 MarR family Tetraspanin PF00335.20 KFM68733.1 - 4.2e-23 82.3 11.3 5.1e-23 82.0 11.3 1.1 1 0 0 1 1 1 1 Tetraspanin family YfhO PF09586.10 KFM68733.1 - 0.029 12.6 0.4 0.037 12.3 0.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Tmp39 PF10271.9 KFM68733.1 - 0.031 13.3 0.2 0.037 13.0 0.2 1.1 1 0 0 1 1 1 0 Putative transmembrane protein DUF3493 PF11998.8 KFM68733.1 - 1 9.6 0.0 1 9.6 0.0 2.7 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 DUF2981 PF11200.8 KFM68733.1 - 3 7.5 9.9 3.9 7.1 9.9 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) TMEM213 PF15192.6 KFM68733.1 - 8.9 6.4 6.7 0.79 9.7 1.1 2.1 2 0 0 2 2 2 0 TMEM213 family ABC2_membrane PF01061.24 KFM68733.1 - 9 5.6 18.9 0.48 9.8 12.4 2.0 2 1 0 2 2 2 0 ABC-2 type transporter Ricin_B_lectin PF00652.22 KFM68735.1 - 4.6e-21 75.4 0.3 6.5e-21 74.9 0.3 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFM68735.1 - 1.4e-05 24.7 0.1 2.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 KFM68735.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 OppC_N PF12911.7 KFM68736.1 - 0.024 14.6 1.8 0.043 13.8 1.8 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF5385 PF17359.2 KFM68736.1 - 0.17 11.4 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) OapA_N PF08525.11 KFM68736.1 - 0.46 10.5 4.4 0.69 9.9 4.4 1.3 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif SNARE PF05739.19 KFM68736.1 - 2.9 8.0 5.5 5.5 7.1 5.5 1.4 1 0 0 1 1 1 0 SNARE domain Fimbrial_PilY2 PF14481.6 KFM68738.1 - 0.078 12.6 0.2 0.078 12.6 0.2 1.1 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Gal-bind_lectin PF00337.22 KFM68738.1 - 0.09 12.3 0.0 0.095 12.2 0.0 1.0 1 0 0 1 1 1 0 Galactoside-binding lectin SOAR PF16533.5 KFM68741.1 - 0.035 14.1 0.1 0.039 13.9 0.1 1.1 1 0 0 1 1 1 0 STIM1 Orai1-activating region Peptidase_C2 PF00648.21 KFM68742.1 - 7.2e-40 136.8 0.0 1.2e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease HTH_Tnp_Tc3_2 PF01498.18 KFM68742.1 - 3.2e-16 59.3 2.2 8e-16 58.1 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68742.1 - 2.1e-13 50.3 0.0 3.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68742.1 - 1.3e-05 24.8 1.8 2.5e-05 24.0 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68742.1 - 0.011 15.5 0.5 0.032 14.0 0.5 1.9 1 0 0 1 1 1 0 Homeodomain-like domain ApoLp-III PF07464.11 KFM68743.1 - 2.2e-06 27.8 15.0 0.0005 20.2 7.0 3.5 2 1 1 3 3 3 1 Apolipophorin-III precursor (apoLp-III) DUF2252 PF10009.9 KFM68743.1 - 2.1e-05 23.8 0.3 2.4e-05 23.6 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) DUF883 PF05957.13 KFM68743.1 - 0.00014 22.4 4.2 0.0049 17.4 0.8 3.0 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KFM68743.1 - 0.00019 21.4 8.8 0.00038 20.4 7.4 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KFM68743.1 - 0.00076 20.0 9.5 1.3 9.6 3.7 3.6 2 1 1 3 3 3 1 YtxH-like protein Baculo_PEP_C PF04513.12 KFM68743.1 - 0.0023 18.0 2.4 0.29 11.2 1.4 2.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 KFM68743.1 - 0.0061 16.4 3.1 0.0061 16.4 3.1 2.7 1 1 2 3 3 3 1 CdvA-like coiled-coil domain SseC PF04888.12 KFM68743.1 - 0.0092 15.6 2.3 0.15 11.6 0.0 2.5 1 1 1 2 2 2 1 Secretion system effector C (SseC) like family FapA PF03961.13 KFM68743.1 - 0.011 14.3 1.7 0.014 14.1 1.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Nbl1_Borealin_N PF10444.9 KFM68743.1 - 0.013 15.1 1.1 31 4.3 0.2 3.4 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Prismane PF03063.20 KFM68743.1 - 0.016 14.0 1.7 0.018 13.7 1.7 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family LOH1CR12 PF10158.9 KFM68743.1 - 0.016 15.2 3.2 0.21 11.6 1.5 2.3 1 1 1 2 2 2 0 Tumour suppressor protein COG5 PF10392.9 KFM68743.1 - 0.023 14.9 8.2 0.51 10.5 1.9 2.5 2 1 1 3 3 2 0 Golgi transport complex subunit 5 VPS53_C PF16854.5 KFM68743.1 - 0.042 13.7 2.6 0.066 13.1 2.6 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus Exonuc_VII_L PF02601.15 KFM68743.1 - 0.043 13.4 0.8 0.05 13.2 0.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phasin PF05597.11 KFM68743.1 - 0.045 13.8 11.2 0.6 10.1 2.2 3.1 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HalX PF08663.10 KFM68743.1 - 0.048 14.0 1.3 4.6 7.6 0.2 2.7 2 1 1 3 3 2 0 HalX domain Perilipin PF03036.16 KFM68743.1 - 0.057 12.4 7.4 0.027 13.5 3.4 1.9 2 0 0 2 2 2 0 Perilipin family Prominin PF05478.11 KFM68743.1 - 0.078 10.9 6.1 0.085 10.8 3.3 2.0 2 0 0 2 2 2 0 Prominin TPD52 PF04201.15 KFM68743.1 - 0.078 12.6 4.6 1 8.9 4.7 2.3 1 1 0 1 1 1 0 Tumour protein D52 family ApoO PF09769.9 KFM68743.1 - 0.095 12.7 1.9 0.58 10.1 0.2 2.6 3 0 0 3 3 3 0 Apolipoprotein O DUF948 PF06103.11 KFM68743.1 - 0.1 12.9 9.9 5.4 7.3 1.6 3.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) PRD PF00874.20 KFM68743.1 - 0.12 12.6 6.5 0.39 11.1 2.8 2.5 1 1 1 2 2 2 0 PRD domain PIN_8 PF18476.1 KFM68743.1 - 0.14 12.0 6.3 0.81 9.5 5.5 2.2 1 1 0 1 1 1 0 PIN like domain PEP-utilisers_N PF05524.13 KFM68743.1 - 0.14 12.3 4.8 2.4 8.4 0.8 3.0 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal Z1 PF10593.9 KFM68743.1 - 0.15 11.6 2.4 0.26 10.7 2.1 1.5 1 1 0 1 1 1 0 Z1 domain GAT PF03127.14 KFM68743.1 - 0.26 11.6 6.0 0.82 10.0 1.8 3.1 2 1 2 4 4 3 0 GAT domain Syntaxin_2 PF14523.6 KFM68743.1 - 0.39 11.1 6.3 8.3 6.9 4.3 3.3 2 1 0 2 2 2 0 Syntaxin-like protein CARD PF00619.21 KFM68743.1 - 0.5 10.4 6.8 0.79 9.8 4.8 2.1 1 1 1 2 2 2 0 Caspase recruitment domain Serine_rich PF08824.10 KFM68743.1 - 0.67 9.9 7.0 8.4 6.4 0.2 3.1 2 2 1 3 3 3 0 Serine rich protein interaction domain DUF2203 PF09969.9 KFM68743.1 - 0.69 10.7 6.5 6.5 7.5 4.8 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AcylCoA_dehyd_C PF12186.8 KFM68743.1 - 0.7 10.0 9.3 2 8.6 0.8 3.7 2 2 2 4 4 4 0 Acyl-CoA dehydrogenase C terminal Sulfatase_C PF14707.6 KFM68743.1 - 1 10.1 2.9 3.1 8.6 1.2 2.1 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Vps54 PF07928.12 KFM68743.1 - 1.1 9.6 6.8 5.8 7.4 0.8 3.0 2 1 1 3 3 3 0 Vps54-like protein RFX5_N PF18326.1 KFM68743.1 - 1.3 8.9 5.7 38 4.1 0.0 3.5 3 1 0 3 3 3 0 RFX5 N-terminal domain DUF2277 PF10041.9 KFM68743.1 - 1.5 9.2 3.9 18 5.7 0.1 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2277) MtrG PF04210.13 KFM68743.1 - 1.5 8.8 6.0 11 6.0 0.9 3.1 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G SKA2 PF16740.5 KFM68743.1 - 1.9 8.3 9.5 17 5.3 7.1 3.2 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Fib_alpha PF08702.10 KFM68743.1 - 2.2 8.4 7.7 2.2 8.5 5.0 2.2 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family DASH_Dad3 PF08656.10 KFM68743.1 - 2.3 8.4 6.3 1.3 9.2 0.3 2.9 1 1 1 2 2 2 0 DASH complex subunit Dad3 LUC7 PF03194.15 KFM68743.1 - 2.5 7.7 6.4 12 5.5 6.3 2.0 1 1 0 1 1 1 0 LUC7 N_terminus Fzo_mitofusin PF04799.13 KFM68743.1 - 2.9 7.4 9.3 1.5 8.3 2.2 2.5 2 1 1 3 3 3 0 fzo-like conserved region DUF1664 PF07889.12 KFM68743.1 - 3.4 7.7 8.7 2.7 8.0 3.5 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DUF3713 PF12506.8 KFM68743.1 - 3.7 7.9 11.5 19 5.6 3.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3713) DUF16 PF01519.16 KFM68743.1 - 4.8 7.7 12.8 3.3e+02 1.8 10.7 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 ISG65-75 PF11727.8 KFM68743.1 - 9.5 5.4 8.6 9 5.4 6.0 2.1 2 1 0 2 2 2 0 Invariant surface glycoprotein HTH_Tnp_Tc3_2 PF01498.18 KFM68744.1 - 1.5e-12 47.6 3.7 2.5e-12 46.8 3.7 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68744.1 - 6.4e-09 35.7 0.0 1.5e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM68744.1 - 6.5 7.5 9.3 0.089 13.4 1.4 2.1 2 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68745.1 - 3.2e-11 43.3 3.1 7.3e-11 42.2 3.1 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68745.1 - 1e-10 41.5 0.0 1.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.18 KFM68745.1 - 0.0093 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain MarR_2 PF12802.7 KFM68745.1 - 0.06 13.2 0.6 0.57 10.1 0.1 2.5 1 1 1 2 2 2 0 MarR family HTH_32 PF13565.6 KFM68745.1 - 0.32 11.6 8.6 0.31 11.7 0.6 2.9 2 1 1 3 3 3 0 Homeodomain-like domain wnt PF00110.19 KFM68746.1 - 2.2e-40 139.2 0.1 2.4e-40 139.0 0.1 1.0 1 0 0 1 1 1 1 wnt family HTH_Tnp_Tc3_2 PF01498.18 KFM68747.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68747.1 - 1.8e-13 50.5 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SNARE PF05739.19 KFM68748.1 - 4.6 7.3 5.9 0.83 9.7 0.5 2.2 2 0 0 2 2 2 0 SNARE domain wnt PF00110.19 KFM68749.1 - 1.1e-22 81.0 0.1 1.2e-22 80.9 0.1 1.0 1 0 0 1 1 1 1 wnt family Atx10homo_assoc PF09759.9 KFM68750.1 - 7.9e-11 41.9 0.0 8.5e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Atx10homo_assoc PF09759.9 KFM68752.1 - 0.00011 22.1 0.0 0.0046 17.0 0.1 3.2 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Granulin PF00396.18 KFM68753.1 - 1.5e-26 92.5 50.2 1.9e-15 56.9 21.9 3.9 4 0 0 4 4 4 2 Granulin RVT_1 PF00078.27 KFM68755.1 - 4.4e-41 140.8 1.2 1.2e-40 139.4 1.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KFM68755.1 - 4.8e-17 62.5 1.0 1.3e-16 61.0 0.0 2.4 2 0 0 2 2 2 1 RNase H Exo_endo_phos_2 PF14529.6 KFM68755.1 - 1.6e-14 53.8 0.1 7.8e-14 51.5 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM68755.1 - 0.0028 17.2 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_N PF13655.6 KFM68755.1 - 0.0074 16.5 0.6 0.019 15.2 0.6 1.7 1 0 0 1 1 1 1 N-terminal domain of reverse transcriptase RVT_3 PF13456.6 KFM68755.1 - 0.021 14.6 0.1 0.052 13.4 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Usher_TcfC PF17271.2 KFM68755.1 - 0.044 12.6 0.1 0.07 11.9 0.1 1.2 1 0 0 1 1 1 0 TcfC Usher-like barrel domain HMG_box PF00505.19 KFM68756.1 - 0.00013 22.3 0.0 0.0002 21.7 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HTH_23 PF13384.6 KFM68757.1 - 1.8e-05 24.4 0.5 1.9e-05 24.3 0.5 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 KFM68757.1 - 6.9e-05 22.5 0.3 0.00013 21.6 0.3 1.6 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM68757.1 - 0.0037 17.1 0.0 0.0043 16.9 0.0 1.1 1 0 0 1 1 1 1 Tc3 transposase HTH_29 PF13551.6 KFM68757.1 - 0.021 14.8 0.8 0.024 14.7 0.8 1.1 1 0 0 1 1 1 0 Winged helix-turn helix HTH_DeoR PF08220.12 KFM68757.1 - 0.031 14.0 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Grp7_allergen PF16984.5 KFM68761.1 - 3.4e-05 24.0 0.0 0.00011 22.3 0.0 1.9 1 1 0 1 1 1 1 Group 7 allergen JHBP PF06585.11 KFM68762.1 - 5.1e-23 81.5 0.0 1.2e-16 60.6 0.0 2.1 2 0 0 2 2 2 2 Haemolymph juvenile hormone binding protein (JHBP) Grp7_allergen PF16984.5 KFM68762.1 - 0.0094 16.0 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 1 Group 7 allergen Grp7_allergen PF16984.5 KFM68763.1 - 3.3e-05 24.0 0.0 0.00019 21.5 0.0 2.2 1 1 0 1 1 1 1 Group 7 allergen HTH_Tnp_Tc3_2 PF01498.18 KFM68764.1 - 8e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68764.1 - 6e-15 55.3 0.0 6.4e-14 51.9 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM68764.1 - 0.00077 20.0 1.5 0.00077 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68764.1 - 0.0032 17.2 0.1 0.12 12.2 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68764.1 - 0.018 15.1 0.1 0.068 13.3 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68764.1 - 0.037 14.0 0.4 0.037 14.0 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix DUF2102 PF09875.9 KFM68764.1 - 0.072 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Mlh1_C PF16413.5 KFM68765.1 - 0.011 15.1 0.2 0.89 8.9 0.2 2.0 1 1 1 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus WD40 PF00400.32 KFM68766.1 - 2.5e-05 24.9 2.2 0.0049 17.7 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat GLTSCR1 PF15249.6 KFM68768.1 - 3.2e-29 101.4 0.1 1.1e-28 99.6 0.1 2.1 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein RUN PF02759.19 KFM68768.1 - 0.068 13.1 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 RUN domain DUF3811 PF11656.8 KFM68768.1 - 0.98 9.8 2.9 1.1 9.7 0.6 2.3 2 0 0 2 2 2 0 YjbD family (DUF3811) cEGF PF12662.7 KFM68769.1 - 0.0022 17.9 0.1 0.0044 16.9 0.1 1.5 1 0 0 1 1 1 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFM68769.1 - 0.035 14.4 0.2 0.056 13.7 0.2 1.3 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site DDE_3 PF13358.6 KFM68770.1 - 8.1e-09 35.4 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease UDPGP PF01704.18 KFM68771.1 - 3.2e-49 167.7 0.0 4e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KFM68771.1 - 0.012 16.0 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain KN_motif PF12075.8 KFM68772.1 - 0.0038 17.0 0.1 0.0054 16.5 0.1 1.2 1 0 0 1 1 1 1 KN motif Band_7 PF01145.25 KFM68773.1 - 9.1e-22 77.9 0.0 9.1e-22 77.9 0.0 3.4 3 1 0 3 3 3 1 SPFH domain / Band 7 family Flot PF15975.5 KFM68773.1 - 5.1e-09 36.4 8.7 5.1e-09 36.4 8.7 3.8 2 2 1 3 3 3 2 Flotillin EphA2_TM PF14575.6 KFM68775.1 - 0.0078 17.1 0.1 0.023 15.6 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain PRIMA1 PF16101.5 KFM68775.1 - 0.01 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TMEM154 PF15102.6 KFM68775.1 - 0.02 14.8 0.7 0.041 13.8 0.1 1.8 2 0 0 2 2 2 0 TMEM154 protein family Shisa PF13908.6 KFM68775.1 - 0.1 12.8 0.7 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator I-set PF07679.16 KFM68776.1 - 6.3e-19 67.8 0.3 1.3e-12 47.6 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain fn3 PF00041.21 KFM68776.1 - 4.2e-17 62.3 1.7 1.4e-16 60.6 0.3 2.3 3 0 0 3 3 3 1 Fibronectin type III domain Ig_3 PF13927.6 KFM68776.1 - 4.6e-13 49.6 0.3 4.4e-09 36.8 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFM68776.1 - 4.9e-12 45.8 0.0 1e-08 35.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM68776.1 - 1.5e-11 44.5 0.1 1.1e-05 25.7 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFM68776.1 - 1.3e-07 31.7 1.7 0.022 14.9 0.0 3.4 3 1 0 3 3 3 2 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFM68776.1 - 2.8e-07 31.0 0.3 6.1e-07 29.9 0.1 1.7 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain C2-set PF05790.15 KFM68776.1 - 0.036 14.3 0.1 1.6 9.0 0.0 2.7 3 0 0 3 3 3 0 Immunoglobulin C2-set domain HTH_Tnp_Tc3_2 PF01498.18 KFM68777.1 - 7.5e-14 51.7 0.2 1.9e-13 50.5 0.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68777.1 - 2.7e-12 46.6 0.0 4.6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 KFM68777.1 - 0.00084 19.3 0.3 0.0046 17.0 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KFM68777.1 - 0.0014 19.2 5.4 0.084 13.5 0.0 3.6 3 1 1 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68777.1 - 0.024 14.8 0.1 0.38 10.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.6 KFM68778.1 - 4.8e-16 58.8 0.1 5.8e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68778.1 - 7.7e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68778.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68778.1 - 0.0024 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68778.1 - 0.014 15.5 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68778.1 - 0.033 14.2 2.6 0.034 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM68779.1 - 7.4e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68779.1 - 1.3e-15 57.5 0.1 1.5e-14 54.0 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM68779.1 - 0.00068 20.2 1.5 0.00068 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68779.1 - 0.0018 18.0 0.3 0.11 12.3 0.0 3.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68779.1 - 0.013 15.7 0.1 0.062 13.4 0.1 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68779.1 - 0.032 14.2 2.6 0.033 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix 7tm_1 PF00001.21 KFM68780.1 - 3.6e-12 46.2 0.7 4.8e-12 45.8 0.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) bacHORMA_2 PF18173.1 KFM68781.1 - 0.092 12.6 0.0 0.094 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial HORMA domain 2 HTH_Tnp_Tc3_2 PF01498.18 KFM68782.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68782.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68782.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68782.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68782.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ion_trans_2 PF07885.16 KFM68783.1 - 0.00065 19.6 0.2 0.022 14.7 0.0 2.2 2 0 0 2 2 2 2 Ion channel Transposase_1 PF01359.18 KFM68784.1 - 2.3e-18 65.8 0.0 3.7e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM68784.1 - 0.00018 21.3 0.0 0.037 13.8 0.1 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease RNA_pol_Rpb2_4 PF04566.13 KFM68784.1 - 1.2 9.4 3.7 23 5.4 0.4 2.4 1 1 1 2 2 2 0 RNA polymerase Rpb2, domain 4 MULE PF10551.9 KFM68785.1 - 2e-14 53.8 5.2 5.8e-14 52.3 0.4 3.0 3 0 0 3 3 3 1 MULE transposase domain zf-C2H2_4 PF13894.6 KFM68785.1 - 0.047 14.5 0.2 0.047 14.5 0.2 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger Hydrolase_3 PF08282.12 KFM68785.1 - 3.2 7.4 7.3 2.8 7.6 0.5 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase EGF PF00008.27 KFM68786.1 - 5.2e-10 39.5 19.7 1.4e-07 31.7 9.0 3.2 3 0 0 3 3 3 2 EGF-like domain EGF_3 PF12947.7 KFM68786.1 - 4.8e-07 29.9 5.1 0.00027 21.1 3.1 2.5 2 0 0 2 2 2 2 EGF domain hEGF PF12661.7 KFM68786.1 - 7.5e-06 26.4 11.4 0.00093 19.7 5.5 2.8 2 0 0 2 2 2 2 Human growth factor-like EGF FXa_inhibition PF14670.6 KFM68786.1 - 4.6e-05 23.6 11.1 0.016 15.5 5.8 2.5 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 KFM68786.1 - 0.00042 20.6 17.5 0.0031 17.8 9.0 3.0 3 0 0 3 3 3 2 EGF-like domain EGF_CA PF07645.15 KFM68786.1 - 0.00073 19.7 21.3 0.00097 19.3 9.3 2.8 2 1 1 3 3 3 2 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 KFM68786.1 - 0.0047 17.2 5.4 0.0047 17.2 5.4 2.9 2 1 0 3 3 3 1 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 KFM68786.1 - 0.0064 16.5 3.2 0.0064 16.5 3.2 2.5 2 0 0 2 2 2 1 MSP1 EGF domain 1 cEGF PF12662.7 KFM68786.1 - 0.25 11.3 12.8 0.2 11.6 0.7 2.7 2 1 0 2 2 2 0 Complement Clr-like EGF-like HR1 PF02185.16 KFM68787.1 - 0.11 12.7 0.4 0.21 11.7 0.4 1.4 1 0 0 1 1 1 0 Hr1 repeat Ribophorin_II PF05817.14 KFM68788.1 - 1.8e-219 730.5 5.1 2.2e-219 730.2 5.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PIG-F PF06699.11 KFM68788.1 - 0.028 14.6 2.3 0.033 14.3 0.1 2.2 3 0 0 3 3 3 0 GPI biosynthesis protein family Pig-F MFS_1 PF07690.16 KFM68789.1 - 4.6e-32 111.3 33.7 5.8e-32 111.0 33.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFM68789.1 - 5.2e-07 28.8 23.5 2.8e-06 26.4 1.6 4.1 1 1 1 2 2 2 2 MFS_1 like family DHODB_Fe-S_bind PF10418.9 KFM68789.1 - 0.079 12.8 2.7 0.18 11.7 2.7 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B HTH_Tnp_Tc3_2 PF01498.18 KFM68791.1 - 2.9e-14 53.1 1.0 5.5e-14 52.2 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68791.1 - 7.3e-14 51.8 0.0 9.4e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease ATP-gua_Ptrans PF00217.19 KFM68792.1 - 1.1e-87 292.9 0.0 1.5e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFM68792.1 - 1.3e-29 102.4 0.0 7.7e-29 99.9 0.0 2.1 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain DUF3158 PF11358.8 KFM68792.1 - 0.089 12.5 0.2 0.26 11.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) tRNA-synt_1d PF00750.19 KFM68794.1 - 2.6e-14 53.0 1.8 3.4e-14 52.6 1.8 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KFM68794.1 - 1.4e-06 28.4 0.1 4.3e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 KFM68796.1 - 5e-11 42.1 0.0 7.2e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.19 KFM68796.1 - 0.0043 16.4 0.0 0.0055 16.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GST_N PF02798.20 KFM68797.1 - 2.2e-16 60.0 0.1 5.7e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFM68797.1 - 8.5e-14 51.6 2.2 1.1e-13 51.2 1.7 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM68797.1 - 5.9e-09 36.0 0.2 1.1e-08 35.1 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM68797.1 - 0.00026 20.9 0.1 0.0014 18.6 0.0 2.3 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFM68797.1 - 0.0072 16.1 0.3 0.022 14.6 0.3 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM68797.1 - 0.032 14.7 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain YHS PF04945.13 KFM68797.1 - 0.39 10.9 0.0 0.39 10.9 0.0 2.3 3 0 0 3 3 3 0 YHS domain GST_N PF02798.20 KFM68798.1 - 1.9e-14 53.8 0.0 3.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFM68798.1 - 0.00063 20.1 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFM68798.1 - 0.023 15.0 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DDE_1 PF03184.19 KFM68800.1 - 4.1e-17 62.4 0.2 6.8e-17 61.7 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM68800.1 - 3.1e-13 49.5 0.5 7e-13 48.4 0.5 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM68800.1 - 0.0042 16.8 0.0 0.014 15.2 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3372 PF11852.8 KFM68800.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Pou PF00157.17 KFM68801.1 - 1e-37 127.9 0.1 1.7e-37 127.2 0.1 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFM68801.1 - 6.6e-19 67.5 0.4 6.6e-19 67.5 0.4 1.8 2 0 0 2 2 2 1 Homeodomain HTH_31 PF13560.6 KFM68801.1 - 0.0096 16.2 0.0 0.099 13.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.11 KFM68801.1 - 0.015 15.2 0.1 0.063 13.2 0.0 2.1 2 0 0 2 2 2 0 Homeobox KN domain ABC_trans_N PF14510.6 KFM68801.1 - 0.12 13.0 0.5 0.28 11.8 0.5 1.6 1 0 0 1 1 1 0 ABC-transporter N-terminal DDE_3 PF13358.6 KFM68803.1 - 4.4e-13 49.2 0.0 6.3e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68803.1 - 3e-06 27.4 0.1 6.7e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_Crp_2 PF13545.6 KFM68803.1 - 0.037 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM68803.1 - 0.069 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KFM68803.1 - 0.078 12.9 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 MarR family DDE_3 PF13358.6 KFM68804.1 - 5.7e-16 58.6 0.1 6.4e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68804.1 - 8.3e-16 58.0 6.5 1.5e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68804.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68804.1 - 0.0021 17.8 0.0 0.093 12.6 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68804.1 - 0.016 15.4 0.1 0.068 13.3 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68804.1 - 0.024 14.7 2.1 0.033 14.2 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM68804.1 - 0.097 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF5335 PF17269.2 KFM68805.1 - 0.21 11.5 0.1 0.41 10.5 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5335) Baculo_PEP_C PF04513.12 KFM68806.1 - 6.8e-06 26.2 0.7 0.0003 20.8 0.4 2.4 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KFM68806.1 - 0.00019 21.3 16.5 0.0015 18.4 13.2 2.6 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF1640 PF07798.11 KFM68806.1 - 0.01 15.9 10.9 0.01 15.9 10.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Phasin PF05597.11 KFM68806.1 - 0.012 15.6 4.8 0.012 15.6 4.8 3.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CLZ PF16526.5 KFM68806.1 - 0.045 14.1 6.0 7.4 7.0 0.7 3.8 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Exonuc_VII_L PF02601.15 KFM68806.1 - 0.054 13.1 7.6 6.1 6.3 0.0 2.4 2 1 0 2 2 2 0 Exonuclease VII, large subunit Peptidase_M75 PF09375.10 KFM68806.1 - 0.075 12.5 6.5 0.042 13.3 4.4 1.6 2 0 0 2 2 2 0 Imelysin MnmE_helical PF12631.7 KFM68806.1 - 0.1 12.7 7.2 0.057 13.6 4.2 2.3 1 1 1 2 2 2 0 MnmE helical domain Mitofilin PF09731.9 KFM68806.1 - 0.27 10.0 17.0 0.037 12.9 13.4 1.3 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Fib_alpha PF08702.10 KFM68806.1 - 0.42 10.8 13.3 0.2 11.8 6.1 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 KFM68806.1 - 0.56 8.1 9.1 1.1 7.1 9.0 1.5 1 1 0 1 1 1 0 Prominin ABC_tran_CTD PF16326.5 KFM68806.1 - 0.7 10.2 8.8 9.5 6.6 0.4 3.6 1 1 1 3 3 3 0 ABC transporter C-terminal domain DUF842 PF05811.13 KFM68806.1 - 2.8 7.6 11.0 1.6 8.4 1.9 2.4 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) ApoO PF09769.9 KFM68806.1 - 3 7.8 8.0 0.72 9.8 1.2 2.8 2 1 1 3 3 3 0 Apolipoprotein O T3SS_needle_F PF09392.10 KFM68806.1 - 3.6 7.8 9.3 1.6 9.0 0.4 3.7 3 2 2 5 5 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF FlaC_arch PF05377.11 KFM68806.1 - 4 7.9 17.2 18 5.9 2.6 4.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KFM68806.1 - 4.9 6.4 8.2 9.9 5.4 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 KFM68806.1 - 5.1 7.2 23.2 29 4.7 8.7 4.3 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Tnp_22_trimer PF17489.2 KFM68806.1 - 8.1 6.5 19.8 0.18 11.8 0.5 4.7 4 1 2 6 6 5 0 L1 transposable element trimerization domain RT_RNaseH_2 PF17919.1 KFM68808.1 - 5.9e-31 106.5 0.0 1.6e-30 105.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM68808.1 - 3.1e-28 98.8 1.2 7.1e-28 97.6 0.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM68808.1 - 4.7e-28 97.5 0.0 1.5e-27 96.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM68808.1 - 7.1e-20 70.9 0.2 2.8e-19 69.0 0.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM68808.1 - 5.7e-18 65.2 0.0 1.6e-15 57.3 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KFM68808.1 - 2.7e-09 37.5 0.0 8.8e-09 35.8 0.0 1.9 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM68808.1 - 1.4e-05 25.7 0.0 3.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM68808.1 - 1.5e-05 25.2 0.0 4.6e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KFM68808.1 - 4.7e-05 23.5 1.0 0.00012 22.2 1.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KFM68808.1 - 7.7e-05 22.5 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_3 PF13456.6 KFM68808.1 - 0.0024 17.7 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Asp_protease PF09668.10 KFM68808.1 - 0.0031 17.3 0.1 0.007 16.2 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease BH4 PF02180.17 KFM68808.1 - 0.057 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 DUF3437 PF11919.8 KFM68808.1 - 0.32 10.9 5.5 6 6.9 0.8 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF3437) Utp11 PF03998.13 KFM68810.1 - 1.6e-59 201.8 25.3 1.9e-59 201.6 25.3 1.0 1 0 0 1 1 1 1 Utp11 protein Ribo_biogen_C PF04034.13 KFM68810.1 - 0.056 13.2 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Ribosome biogenesis protein, C-terminal SLATT_5 PF18160.1 KFM68810.1 - 0.36 10.1 13.2 0.042 13.2 6.1 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 MRPL52 PF18699.1 KFM68810.1 - 3.8 7.8 11.0 0.77 10.0 0.8 3.2 3 0 0 3 3 3 0 Mitoribosomal protein mL52 NMD3 PF04981.13 KFM68812.1 - 9.5e-81 270.8 6.8 1.4e-80 270.3 6.8 1.2 1 0 0 1 1 1 1 NMD3 family DUF1289 PF06945.13 KFM68812.1 - 0.17 11.7 2.8 6.9 6.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) NinF PF05810.12 KFM68812.1 - 2.5 8.0 6.6 1.1 9.2 0.3 3.1 3 0 0 3 3 3 0 NinF protein DZR PF12773.7 KFM68812.1 - 7.5 6.7 11.5 3.8e+02 1.2 11.5 2.9 1 1 0 1 1 1 0 Double zinc ribbon DUF3053 PF11254.8 KFM68813.1 - 0.058 13.0 0.7 0.12 11.9 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3053) Chal_sti_synt_N PF00195.19 KFM68813.1 - 0.19 11.2 1.9 0.29 10.5 0.6 1.7 1 1 1 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain BRE1 PF08647.11 KFM68813.1 - 0.73 9.9 5.5 0.23 11.6 1.0 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HisK_sensor PF18698.1 KFM68813.1 - 1.4 9.3 12.1 0.3 11.5 6.4 2.2 1 1 1 2 2 2 0 Histidine kinase sensor domain Phage_HK97_TLTM PF06120.11 KFM68813.1 - 5.7 6.0 9.6 1.8 7.7 1.0 2.0 1 1 1 2 2 2 0 Tail length tape measure protein DUF1759 PF03564.15 KFM68814.1 - 1.7e-19 70.3 0.1 2.3e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) RRM_1 PF00076.22 KFM68815.1 - 3e-40 135.9 0.0 2.3e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM68815.1 - 2.2e-06 27.7 0.1 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KFM68815.1 - 9.4e-05 22.0 0.0 0.1 12.2 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KFM68815.1 - 0.022 14.4 0.2 0.51 10.1 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Longin PF13774.6 KFM68816.1 - 9.8e-26 89.6 0.4 2.6e-25 88.3 0.4 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KFM68816.1 - 1.4e-15 56.8 0.4 3.7e-15 55.5 0.2 1.7 2 0 0 2 2 2 1 Synaptobrevin Sec20 PF03908.13 KFM68816.1 - 0.0058 16.5 0.8 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Sec20 BTB PF00651.31 KFM68817.1 - 2.5e-10 40.6 0.0 4.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF5318 PF17249.2 KFM68817.1 - 0.71 9.6 3.2 1.7 8.4 0.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5318) BTB PF00651.31 KFM68818.1 - 2.5e-43 146.8 0.8 5e-29 100.8 0.4 2.4 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM68818.1 - 2.3e-06 27.6 0.7 0.00058 19.9 0.3 2.8 2 0 0 2 2 2 2 BTB And C-terminal Kelch BTB_3 PF16017.5 KFM68818.1 - 0.014 15.5 0.1 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 BTB/POZ domain Skp1_POZ PF03931.15 KFM68818.1 - 0.025 14.7 0.1 1.9 8.7 0.0 2.8 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain DUF3219 PF11514.8 KFM68818.1 - 0.075 13.1 0.0 3.4 7.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3219) BTB PF00651.31 KFM68819.1 - 7e-36 122.8 0.2 4.8e-25 88.0 0.1 2.7 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM68819.1 - 0.00051 20.1 0.6 0.0022 18.1 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch MATH PF00917.26 KFM68819.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.8 3 1 0 3 3 3 0 MATH domain TonB_C PF03544.14 KFM68819.1 - 0.18 12.3 0.0 15 6.1 0.0 2.7 2 0 0 2 2 2 0 Gram-negative bacterial TonB protein C-terminal BTB PF00651.31 KFM68820.1 - 4.9e-38 129.8 0.3 1e-26 93.3 0.2 2.4 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM68820.1 - 0.0056 16.8 0.9 0.03 14.4 0.1 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF4952 PF16310.5 KFM68820.1 - 0.065 13.5 1.1 0.24 11.7 0.4 2.2 2 0 0 2 2 2 0 Domian of unknown function (DUF4952) DUF1758 PF05585.12 KFM68821.1 - 5.4e-06 26.3 0.1 7.5e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 KFM68822.1 - 2.6e-05 24.2 0.6 4.5e-05 23.5 0.6 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain BTB PF00651.31 KFM68823.1 - 1.9e-37 127.9 1.6 8.8e-26 90.3 0.7 2.6 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM68823.1 - 0.0011 19.0 0.2 0.0011 19.0 0.2 3.2 4 0 0 4 4 4 1 BTB And C-terminal Kelch DUF3931 PF13082.6 KFM68823.1 - 0.0066 16.6 0.7 0.019 15.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3931) T2SSE PF00437.20 KFM68824.1 - 0.027 13.5 0.0 0.027 13.5 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KFM68824.1 - 0.054 13.0 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KFM68824.1 - 0.072 12.8 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 KFM68824.1 - 0.094 12.0 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 KaiC zf-CCHC PF00098.23 KFM68825.1 - 3.1e-05 23.8 1.8 5.9e-05 23.0 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 KFM68825.1 - 0.00019 21.9 0.0 0.00053 20.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SCAN PF02023.17 KFM68825.1 - 0.00036 20.3 1.7 0.00039 20.2 0.0 2.0 2 0 0 2 2 2 1 SCAN domain Asp_protease_2 PF13650.6 KFM68825.1 - 0.0031 18.1 0.0 0.0084 16.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF5384 PF17358.2 KFM68825.1 - 0.0041 17.2 12.8 0.011 15.8 12.8 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5384) Phage_sheath_1C PF17482.2 KFM68825.1 - 0.0048 16.8 0.1 0.0048 16.8 0.1 2.3 2 0 0 2 2 2 1 Phage tail sheath C-terminal domain RVP PF00077.20 KFM68825.1 - 0.0052 17.1 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1667 PF07892.11 KFM68825.1 - 0.039 14.0 1.2 0.039 14.0 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1667) HET-s_218-289 PF11558.8 KFM68825.1 - 0.044 13.8 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Het-s 218-289 zf-CCHC_4 PF14392.6 KFM68825.1 - 0.12 12.1 1.1 0.28 10.9 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle HTH_Tnp_Tc3_2 PF01498.18 KFM68827.1 - 2.2e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68827.1 - 8.9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease FMO-like PF00743.19 KFM68828.1 - 2.2e-180 600.6 0.1 2.4e-180 600.4 0.1 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM68828.1 - 2.9e-26 92.4 0.1 8.7e-22 77.7 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM68828.1 - 5.6e-17 61.9 0.0 1.3e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM68828.1 - 7.1e-10 38.6 0.5 4.7e-07 29.3 0.0 3.3 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFM68828.1 - 3e-06 27.7 3.0 0.15 12.7 0.0 3.7 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM68828.1 - 7.1e-06 26.2 0.3 2.1e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFM68828.1 - 8.5e-06 25.2 0.3 0.0066 15.7 0.1 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KFM68828.1 - 1.1e-05 25.2 0.2 0.63 9.6 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 KFM68828.1 - 3.2e-05 23.2 1.1 0.035 13.2 0.2 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A IlvN PF07991.12 KFM68828.1 - 6.3e-05 22.6 0.1 0.0079 15.8 0.0 2.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_2 PF00890.24 KFM68828.1 - 0.00011 21.4 4.2 0.00024 20.3 0.7 2.4 2 1 1 3 3 3 1 FAD binding domain Peptidase_M17_N PF02789.17 KFM68828.1 - 0.00024 20.9 0.1 0.002 18.0 0.0 2.2 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain HI0933_like PF03486.14 KFM68828.1 - 0.00034 19.4 3.0 0.0048 15.6 0.7 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KFM68828.1 - 0.00038 20.5 0.3 0.16 11.9 0.0 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KFM68828.1 - 0.0011 18.3 0.1 0.24 10.7 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KFM68828.1 - 0.004 16.5 2.4 0.0093 15.4 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFM68828.1 - 0.006 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KFM68828.1 - 0.011 15.2 0.2 0.88 8.9 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KFM68828.1 - 0.02 14.8 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KFM68828.1 - 0.1 12.6 0.1 4.9 7.2 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KFM68828.1 - 0.15 11.3 0.6 0.68 9.1 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM68829.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68829.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68829.1 - 2e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68829.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68829.1 - 0.026 14.6 0.4 0.087 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM68829.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ATP-gua_Ptrans PF00217.19 KFM68830.1 - 6.8e-87 290.4 0.0 9.9e-87 289.9 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFM68830.1 - 7.5e-32 109.5 0.0 6.7e-31 106.5 0.0 2.2 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain SIR4_SID PF16991.5 KFM68830.1 - 0.15 12.1 0.2 0.27 11.3 0.2 1.3 1 0 0 1 1 1 0 Sir4 SID domain HTH_Tnp_Tc3_2 PF01498.18 KFM68833.1 - 9.3e-10 38.6 2.6 2.1e-09 37.5 2.6 1.6 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 KFM68833.1 - 5.8e-05 22.8 0.7 5.8e-05 22.8 0.7 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM68833.1 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Tc3 transposase HTH_32 PF13565.6 KFM68833.1 - 0.12 12.9 7.9 0.65 10.6 3.5 2.5 1 1 1 2 2 2 0 Homeodomain-like domain HTH_23 PF13384.6 KFM68833.1 - 0.85 9.5 5.4 0.21 11.4 0.4 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68834.1 - 5.2e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68834.1 - 2.3e-13 50.1 0.0 4.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68834.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68834.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68834.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain BACK PF07707.15 KFM68835.1 - 1e-13 51.2 4.8 1.4e-11 44.4 1.3 3.3 2 1 1 3 3 3 2 BTB And C-terminal Kelch BTB PF00651.31 KFM68835.1 - 0.00076 19.7 0.5 0.0031 17.7 0.5 2.0 1 0 0 1 1 1 1 BTB/POZ domain MTS_N PF08468.11 KFM68835.1 - 0.017 15.2 0.4 0.04 14.0 0.4 1.6 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Ferritin PF00210.24 KFM68836.1 - 9.5e-36 122.8 2.2 1.1e-35 122.6 2.2 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KFM68836.1 - 3.3e-06 27.5 0.4 4.3e-06 27.2 0.4 1.3 1 0 0 1 1 1 1 Rubrerythrin FCH PF00611.23 KFM68836.1 - 0.047 14.0 0.9 0.11 12.7 0.9 1.8 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain HTH_Tnp_Tc3_2 PF01498.18 KFM68837.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68837.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68837.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68837.1 - 0.0024 17.6 0.6 0.0068 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68837.1 - 1.8 9.2 15.7 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Acyl_transf_3 PF01757.22 KFM68839.1 - 7.8e-07 28.5 17.9 1e-06 28.1 17.9 1.1 1 0 0 1 1 1 1 Acyltransferase family COQ7 PF03232.13 KFM68839.1 - 0.024 14.4 0.9 2 8.2 0.1 2.2 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 DUF5357 PF17310.2 KFM68839.1 - 0.08 11.5 0.0 0.08 11.5 0.0 2.3 3 1 0 3 3 3 0 Family of unknown function (DUF5357) DUF2856 PF11043.8 KFM68843.1 - 0.028 14.5 0.3 0.043 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Defensin_beta_2 PF13841.6 KFM68843.1 - 1.9 9.1 6.4 0.25 11.9 1.3 2.1 2 0 0 2 2 2 0 Beta defensin SOUL PF04832.12 KFM68844.1 - 7e-48 163.0 0.0 8e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein Ubiquitin_2 PF14560.6 KFM68844.1 - 0.18 12.3 0.0 0.79 10.2 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain Peptidase_S66 PF02016.15 KFM68845.1 - 0.1 12.7 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain RINGv PF12906.7 KFM68846.1 - 1.5e-13 50.7 4.4 3.8e-13 49.3 4.4 1.8 1 0 0 1 1 1 1 RING-variant domain DUF1084 PF06454.11 KFM68846.1 - 1.1e-05 24.9 11.0 1.7e-05 24.3 11.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) EGF_Tenascin PF18720.1 KFM68846.1 - 0.0065 16.5 12.7 0.017 15.1 12.7 1.8 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 KFM68846.1 - 0.23 11.9 17.1 0.6 10.5 17.1 1.8 1 0 0 1 1 1 0 EGF-like domain CwfJ_C_1 PF04677.15 KFM68848.1 - 2.4e-32 111.4 0.1 4.7e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KFM68848.1 - 1.4e-08 35.5 0.1 3.4e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF4817 PF16087.5 KFM68849.1 - 3e-10 39.7 0.3 5.6e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) HTH_23 PF13384.6 KFM68849.1 - 6.4e-05 22.6 0.3 0.017 14.9 0.1 2.6 3 0 0 3 3 3 2 Homeodomain-like domain HTH_32 PF13565.6 KFM68849.1 - 0.00029 21.4 0.2 0.0007 20.2 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68849.1 - 0.0023 18.0 0.1 0.61 10.3 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain CENP-B_N PF04218.13 KFM68849.1 - 0.0049 16.5 0.2 0.027 14.1 0.0 2.3 3 0 0 3 3 3 1 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 KFM68849.1 - 0.027 14.5 0.3 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM68849.1 - 0.055 13.7 0.2 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 Transposase HTH_24 PF13412.6 KFM68849.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 KFM68850.1 - 3.9e-16 59.0 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68850.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68850.1 - 3.1e-07 30.0 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68850.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68850.1 - 0.033 14.3 0.4 0.098 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM68850.1 - 2.8 8.6 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Laminin_G_2 PF02210.24 KFM68851.1 - 4.1e-25 88.8 0.1 5.4e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM68851.1 - 1.7e-22 80.1 0.0 2.4e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 KFM68851.1 - 0.00013 22.2 10.4 0.00022 21.5 10.4 1.4 1 0 0 1 1 1 1 EGF-like domain TRI12 PF06609.13 KFM68851.1 - 0.071 11.5 0.2 0.09 11.2 0.2 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Laminin_G_3 PF13385.6 KFM68851.1 - 0.076 13.2 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 KFM68852.1 - 7.7e-28 97.6 0.0 8.5e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM68852.1 - 1.3e-23 83.7 0.0 1.6e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFM68852.1 - 0.017 15.3 0.1 0.019 15.1 0.1 1.1 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 KFM68853.1 - 2.4e-05 24.9 0.0 2.8e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM68853.1 - 0.002 18.3 0.0 0.0023 18.1 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain HTH_Tnp_Tc3_2 PF01498.18 KFM68854.1 - 4.3e-16 58.9 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68854.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68854.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68854.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68854.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain eIF2_C PF09173.11 KFM68855.1 - 2e-36 124.1 0.3 6.3e-36 122.5 0.3 1.9 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KFM68855.1 - 6.6e-23 81.3 0.7 6.5e-22 78.0 0.7 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFM68855.1 - 2.8e-13 50.0 0.9 6.8e-13 48.8 0.9 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KFM68855.1 - 0.0009 19.2 0.6 0.012 15.5 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFM68855.1 - 0.0039 17.2 0.0 0.01 15.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KFM68855.1 - 0.022 14.8 0.2 0.047 13.7 0.2 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SLAIN PF15301.6 KFM68856.1 - 1.2e-12 47.9 19.0 1.2e-12 47.9 19.0 2.2 1 1 1 2 2 2 1 SLAIN motif-containing family DDE_Tnp_4 PF13359.6 KFM68856.1 - 0.1 12.2 0.1 0.29 10.8 0.1 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_48 PF17906.1 KFM68857.1 - 2.7e-09 37.0 0.0 4.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM68857.1 - 3.3e-06 27.6 8.0 6e-05 23.6 1.5 3.3 2 1 1 3 3 3 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KFM68857.1 - 0.00091 18.7 0.2 0.0024 17.3 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 KFM68857.1 - 0.001 18.8 0.0 0.0067 16.2 0.0 2.3 2 0 0 2 2 2 1 HTH DNA binding domain HTH_23 PF13384.6 KFM68857.1 - 0.0011 18.7 2.3 0.054 13.3 0.2 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_17 PF12728.7 KFM68857.1 - 0.0015 18.6 0.1 0.091 13.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KFM68857.1 - 0.005 16.8 0.4 0.011 15.7 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM68857.1 - 0.008 15.6 0.0 0.034 13.5 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 KFM68857.1 - 0.0092 15.5 0.1 0.023 14.2 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 KFM68857.1 - 0.017 15.4 4.2 0.021 15.0 1.2 2.6 2 2 1 3 3 3 0 Transposase PCI PF01399.27 KFM68857.1 - 0.018 15.6 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 PCI domain ANT PF03374.14 KFM68857.1 - 0.025 14.9 0.1 0.04 14.2 0.1 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain Sigma70_r3 PF04539.16 KFM68857.1 - 0.029 14.5 0.3 0.085 13.0 0.0 1.9 3 0 0 3 3 1 0 Sigma-70 region 3 HTH_28 PF13518.6 KFM68857.1 - 0.038 14.1 2.0 1.1 9.4 0.1 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Mga PF08280.11 KFM68857.1 - 0.042 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF3071 PF11268.8 KFM68857.1 - 0.18 11.8 6.5 0.16 12.0 5.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3071) VIT1 PF01988.19 KFM68857.1 - 0.89 9.4 2.4 5 6.9 2.4 2.1 1 1 1 2 2 2 0 VIT family Kelch_1 PF01344.25 KFM68858.1 - 5.6e-66 217.9 13.9 3.9e-16 58.4 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFM68858.1 - 2.4e-39 132.4 6.4 7.5e-08 32.4 0.2 6.4 2 2 4 6 6 6 6 Kelch motif BTB PF00651.31 KFM68858.1 - 1.6e-32 112.0 1.9 3.1e-32 111.1 1.3 1.9 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM68858.1 - 1.1e-31 109.0 1.8 1.1e-31 109.0 1.8 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFM68858.1 - 2e-26 90.9 10.0 3.2e-06 26.9 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KFM68858.1 - 9.4e-22 76.8 3.0 0.004 17.4 0.2 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFM68858.1 - 1.1e-17 63.7 5.0 0.00019 21.4 0.0 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM68858.1 - 1.1e-15 57.2 6.4 0.0073 16.3 0.0 5.8 5 0 0 5 5 5 5 Kelch motif DUF3342 PF11822.8 KFM68858.1 - 0.0044 17.2 0.5 0.013 15.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) HTH_Tnp_Tc3_2 PF01498.18 KFM68859.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68859.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68859.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68859.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68859.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain FARP PF01581.16 KFM68860.1 - 0.01 16.2 1.1 12 7.0 0.1 3.0 2 0 0 2 2 2 0 FMRFamide related peptide family Lambda_tail_I PF06805.12 KFM68860.1 - 0.15 12.4 0.1 1.3 9.4 0.0 2.1 1 1 1 2 2 2 0 Bacteriophage lambda tail assembly protein I Lactamase_B_6 PF16661.5 KFM68862.1 - 6.3e-05 22.5 0.1 7.9e-05 22.2 0.1 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFM68862.1 - 0.0025 17.1 0.0 0.0029 16.9 0.0 1.1 1 0 0 1 1 1 1 Putative beta-lactamase-like family Thioredoxin PF00085.20 KFM68865.1 - 1.6e-60 201.5 0.0 1.3e-30 105.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KFM68865.1 - 3.1e-08 34.0 2.2 0.013 15.9 0.1 4.2 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM68865.1 - 1.2e-05 25.5 0.1 0.43 10.9 0.0 4.0 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KFM68865.1 - 2e-05 24.6 0.0 0.4 10.9 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KFM68865.1 - 0.00013 21.9 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 KFM68865.1 - 0.00044 20.0 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 KFM68865.1 - 0.0021 18.1 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain DDE_Tnp_1_2 PF13586.6 KFM68865.1 - 0.0062 16.9 0.0 8.1 6.9 0.0 3.2 2 1 0 2 2 2 1 Transposase DDE domain TraF PF13728.6 KFM68865.1 - 0.027 14.3 0.0 3.8 7.3 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein zf-FLZ PF04570.14 KFM68866.1 - 2.4 7.7 7.9 2 7.9 0.0 4.1 5 0 0 5 5 5 0 zinc-finger of the FCS-type, C2-C2 YabA PF06156.13 KFM68870.1 - 0.0078 16.8 2.2 0.009 16.6 2.2 1.1 1 0 0 1 1 1 1 Initiation control protein YabA GIT_CC PF16559.5 KFM68870.1 - 0.052 13.4 2.7 0.12 12.2 2.6 1.7 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 KFM68870.1 - 0.24 11.5 4.5 0.21 11.7 1.0 2.0 2 0 0 2 2 2 0 bZIP transcription factor Fip1 PF05182.13 KFM68871.1 - 1.7e-25 88.3 2.3 2.7e-25 87.6 2.3 1.4 1 0 0 1 1 1 1 Fip1 motif RXT2_N PF08595.11 KFM68871.1 - 0.52 10.3 4.5 0.81 9.7 4.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Defensin_propep PF00879.18 KFM68871.1 - 7.1 7.0 5.0 19 5.6 5.0 1.7 1 0 0 1 1 1 0 Defensin propeptide TAFII55_N PF04658.13 KFM68872.1 - 1.4e-54 184.1 0.9 1.4e-54 184.1 0.9 2.0 2 0 0 2 2 2 1 TAFII55 protein conserved region DUF3850 PF12961.7 KFM68872.1 - 0.096 12.7 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) Big_3_3 PF13750.6 KFM68873.1 - 0.00031 20.4 0.9 0.014 15.0 0.1 2.8 3 0 0 3 3 3 2 Bacterial Ig-like domain (group 3) Ninjurin PF04923.12 KFM68874.1 - 2.8e-22 78.6 4.1 4.1e-22 78.1 4.1 1.2 1 0 0 1 1 1 1 Ninjurin DUF5453 PF17534.2 KFM68874.1 - 0.024 14.6 1.9 0.034 14.1 1.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5453) DUF4231 PF14015.6 KFM68874.1 - 0.088 13.3 0.9 0.21 12.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Ninjurin PF04923.12 KFM68875.1 - 2.6e-24 85.1 2.9 3.3e-24 84.8 2.9 1.1 1 0 0 1 1 1 1 Ninjurin DUF5383 PF17355.2 KFM68875.1 - 0.12 12.7 1.1 0.19 12.1 1.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5383) bZIP_2 PF07716.15 KFM68876.1 - 7.9e-14 51.5 9.3 1.2e-13 50.9 9.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM68876.1 - 5.8e-06 26.3 10.2 9e-06 25.7 10.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFM68876.1 - 0.011 16.2 5.3 0.017 15.6 5.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DnaJ PF00226.31 KFM68877.1 - 3.9e-16 58.9 0.7 6.6e-16 58.2 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain TM2 PF05154.16 KFM68877.1 - 2e-09 37.6 15.0 2e-09 37.6 15.0 2.1 2 0 0 2 2 2 1 TM2 domain HTH_23 PF13384.6 KFM68878.1 - 0.00024 20.8 0.1 0.027 14.3 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain DUF4817 PF16087.5 KFM68878.1 - 0.0055 16.5 0.4 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) HTH_28 PF13518.6 KFM68878.1 - 0.1 12.7 0.0 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 KFM68878.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB zf-C2H2_4 PF13894.6 KFM68880.1 - 4.4e-08 33.3 12.6 0.0003 21.4 3.2 2.9 2 1 1 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM68880.1 - 2e-07 31.1 14.1 8.6e-06 25.9 4.4 3.0 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KFM68880.1 - 0.0015 18.8 7.2 0.002 18.4 7.2 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFM68880.1 - 0.0028 17.9 6.1 0.01 16.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM68880.1 - 0.0095 16.3 2.1 0.49 10.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM68880.1 - 0.02 14.9 2.8 0.02 14.9 2.8 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 KFM68880.1 - 0.04 13.9 0.9 0.061 13.3 0.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF3039 PF11238.8 KFM68880.1 - 0.047 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-H2C2_2 PF13465.6 KFM68880.1 - 0.048 14.1 4.2 0.048 14.1 4.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Spt46 PF17734.1 KFM68880.1 - 0.069 13.0 0.8 0.084 12.7 0.8 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 GAGA PF09237.11 KFM68880.1 - 0.22 11.3 3.2 1.3 8.9 0.9 2.2 1 1 1 2 2 2 0 GAGA factor zf-MYST PF17772.1 KFM68880.1 - 0.57 9.8 6.2 0.53 9.9 0.9 2.2 2 0 0 2 2 2 0 MYST family zinc finger domain zf-BED PF02892.15 KFM68880.1 - 1.9 8.6 11.1 1.2 9.3 2.4 2.4 1 1 1 2 2 2 0 BED zinc finger DUF2256 PF10013.9 KFM68880.1 - 3.3 7.9 6.9 2.8 8.1 1.0 2.4 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 KFM68880.1 - 3.6 7.8 11.1 8.5 6.6 2.6 2.2 1 1 1 2 2 2 0 FYVE zinc finger GTP_cyclohydro2 PF00925.20 KFM68882.1 - 0.0045 16.6 0.0 0.0047 16.5 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase II Sugar_tr PF00083.24 KFM68883.1 - 7.4e-25 87.7 8.7 8.1e-25 87.6 8.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PRA1 PF03208.19 KFM68883.1 - 0.14 11.8 4.1 0.23 11.1 3.6 1.6 1 1 1 2 2 2 0 PRA1 family protein NAD_binding_5 PF07994.12 KFM68884.1 - 6.3e-148 492.4 0.0 7.6e-148 492.2 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KFM68884.1 - 1.4e-48 163.6 0.1 2.5e-48 162.8 0.1 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF4041 PF13250.6 KFM68884.1 - 0.053 13.4 0.3 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) DDE_3 PF13358.6 KFM68885.1 - 2.7e-12 46.7 0.0 4.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68885.1 - 9e-11 41.9 2.6 1.9e-10 40.8 2.6 1.6 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.6 KFM68885.1 - 0.0037 16.9 0.3 0.0098 15.5 0.3 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_12 PF08461.10 KFM68885.1 - 0.022 14.7 0.8 0.035 14.1 0.1 1.7 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain ecTbetaR2 PF08917.10 KFM68885.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain zf-H2C2_2 PF13465.6 KFM68888.1 - 7.2e-48 159.0 49.9 4.7e-08 33.1 0.3 8.8 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68888.1 - 3.4e-38 128.0 64.2 8.6e-06 25.9 1.1 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68888.1 - 1.1e-27 94.4 56.8 0.00094 19.8 0.7 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM68888.1 - 3.9e-19 68.4 49.6 0.0031 17.8 0.6 8.5 7 1 1 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM68888.1 - 3.1e-14 52.8 30.7 0.15 12.4 0.2 8.3 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM68888.1 - 3.9e-11 42.7 44.6 0.057 13.4 1.1 8.4 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM68888.1 - 6.6e-07 29.0 36.1 0.071 12.9 0.5 7.2 8 0 0 8 8 7 4 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM68888.1 - 6.8e-06 25.9 28.5 0.2 11.6 0.3 7.5 8 0 0 8 8 7 2 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM68888.1 - 4.4e-05 23.5 24.2 1.9 8.6 0.1 7.0 6 1 1 7 7 7 1 Sec23/Sec24 zinc finger BolA PF01722.18 KFM68888.1 - 0.0004 20.6 10.2 0.72 10.2 0.1 5.6 1 1 4 6 6 6 2 BolA-like protein GAGA PF09237.11 KFM68888.1 - 0.0026 17.5 17.1 0.36 10.7 0.0 5.7 1 1 6 7 7 7 2 GAGA factor Ribosomal_L21e PF01157.18 KFM68888.1 - 0.0064 16.3 0.7 0.053 13.4 0.1 2.5 1 1 2 3 3 3 1 Ribosomal protein L21e C1_1 PF00130.22 KFM68888.1 - 0.024 14.5 34.1 8.2 6.4 6.1 6.8 1 1 5 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.7 KFM68888.1 - 0.027 14.8 47.4 2.3 8.6 0.7 7.8 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) DHHA2 PF02833.14 KFM68888.1 - 0.033 14.4 0.1 0.2 11.8 0.0 2.0 1 1 1 2 2 2 0 DHHA2 domain zf-C2H2_9 PF16293.5 KFM68888.1 - 0.047 13.5 29.5 1 9.3 0.4 7.3 2 1 6 8 8 8 0 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 KFM68888.1 - 0.084 12.9 21.7 0.69 9.9 0.6 5.1 4 2 2 6 6 6 0 Adenylate kinase, active site lid zf-CHCC PF10276.9 KFM68888.1 - 0.093 12.8 7.1 32 4.7 0.0 5.9 7 0 0 7 7 7 0 Zinc-finger domain zf-RRPl_C4 PF17026.5 KFM68888.1 - 0.097 12.8 24.9 0.17 12.0 3.9 3.6 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type HNH_5 PF14279.6 KFM68888.1 - 0.21 11.4 33.0 9.8 6.1 3.9 7.0 3 3 1 4 4 4 0 HNH endonuclease zf-DBF PF07535.12 KFM68888.1 - 0.27 11.4 24.2 2.5 8.3 0.1 6.3 7 0 0 7 7 7 0 DBF zinc finger Prok-RING_1 PF14446.6 KFM68888.1 - 0.5 10.3 28.0 5.8 6.9 0.1 7.1 7 1 1 8 8 7 0 Prokaryotic RING finger family 1 zf-RING_11 PF17123.5 KFM68888.1 - 0.51 10.1 19.9 4.1 7.2 2.2 6.2 7 0 0 7 7 7 0 RING-like zinc finger zf-LYAR PF08790.11 KFM68888.1 - 0.61 10.0 19.4 8.7 6.4 0.1 6.8 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger zinc_ribbon_15 PF17032.5 KFM68888.1 - 0.8 10.5 23.9 5.9 7.7 0.8 3.9 1 1 3 4 4 4 0 zinc-ribbon family Zf_RING PF16744.5 KFM68888.1 - 1.2 9.3 30.2 7.4 6.8 0.1 6.8 1 1 3 4 4 4 0 KIAA1045 RING finger zf-C2H2_11 PF16622.5 KFM68888.1 - 1.7 8.4 30.1 0.73 9.6 1.1 5.9 6 0 0 6 6 6 0 zinc-finger C2H2-type DUF4764 PF15961.5 KFM68888.1 - 2.1 6.9 19.6 4.1 6.0 0.5 4.8 1 1 2 5 5 5 0 Domain of unknown function (DUF4764) zf-MYST PF17772.1 KFM68888.1 - 4.4 7.0 31.5 1.9 8.2 0.1 7.0 5 2 3 8 8 7 0 MYST family zinc finger domain DUF2256 PF10013.9 KFM68888.1 - 4.8 7.4 26.0 25 5.1 0.1 7.2 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) SoxD PF04267.12 KFM68890.1 - 0.074 13.2 0.1 0.084 13.0 0.1 1.1 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family HTH_24 PF13412.6 KFM68892.1 - 0.0024 17.4 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KFM68892.1 - 0.035 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain GerE PF00196.19 KFM68892.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_20 PF12840.7 KFM68892.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain BTB PF00651.31 KFM68893.1 - 0.00012 22.3 0.2 0.00021 21.5 0.2 1.5 1 1 0 1 1 1 1 BTB/POZ domain DUF2111 PF09884.9 KFM68893.1 - 0.013 15.6 0.1 0.015 15.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) Skp1_POZ PF03931.15 KFM68893.1 - 0.066 13.4 0.1 0.14 12.4 0.1 1.6 2 1 0 2 2 2 0 Skp1 family, tetramerisation domain NP1-WLL PF11733.8 KFM68895.1 - 0.078 12.7 0.1 0.085 12.6 0.1 1.0 1 0 0 1 1 1 0 Non-capsid protein NP1 CholecysA-Rec_N PF09193.10 KFM68895.1 - 0.092 12.8 0.1 0.26 11.3 0.1 1.7 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal DDE_3 PF13358.6 KFM68896.1 - 1.7e-14 53.8 0.0 2.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68896.1 - 5e-14 52.3 0.4 9.3e-14 51.4 0.4 1.4 1 0 0 1 1 1 1 Transposase Peptidase_M3 PF01432.20 KFM68897.1 - 5.3e-105 352.3 0.0 6.4e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M32 PF02074.15 KFM68897.1 - 0.013 14.3 0.3 0.19 10.4 0.2 2.3 2 1 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase Aldose_epim PF01263.20 KFM68899.1 - 2.9e-46 158.2 0.2 3.3e-46 158.0 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase E1-E2_ATPase PF00122.20 KFM68900.1 - 9.2e-22 77.4 0.0 3.3e-21 75.6 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase DUF805 PF05656.14 KFM68900.1 - 2 8.8 6.7 19 5.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF805) Hydrolase PF00702.26 KFM68901.1 - 3.7e-11 43.7 0.0 0.00031 21.1 0.0 2.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM68901.1 - 0.00026 20.8 0.4 0.38 10.5 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFM68901.1 - 0.00036 20.6 0.3 0.0016 18.5 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) DrrA_P4M PF14860.6 KFM68901.1 - 0.1 12.5 0.3 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Sas10_Utp3 PF04000.15 KFM68901.1 - 0.36 11.5 5.1 35 5.1 0.0 3.7 3 1 0 3 3 3 0 Sas10/Utp3/C1D family Dynein_light PF01221.18 KFM68902.1 - 7.4e-20 71.1 0.3 8.1e-20 70.9 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4728 PF15860.5 KFM68903.1 - 0.008 16.8 0.5 0.008 16.8 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4728) REF PF05755.12 KFM68903.1 - 0.026 14.3 0.1 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Kei1 PF08552.11 KFM68903.1 - 0.11 12.3 0.2 0.11 12.3 0.2 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LAX PF15681.5 KFM68903.1 - 0.16 10.7 0.1 0.16 10.7 0.1 1.0 1 0 0 1 1 1 0 Lymphocyte activation family X Pyridoxal_deC PF00282.19 KFM68904.1 - 9.2e-130 432.7 0.0 1e-129 432.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KFM68904.1 - 0.0032 16.7 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFM68904.1 - 0.027 13.7 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase SepSecS PF05889.13 KFM68904.1 - 0.067 11.9 0.0 0.099 11.3 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS zf-H2C2_2 PF13465.6 KFM68906.1 - 1.4e-59 196.0 70.0 4.9e-09 36.2 1.5 9.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68906.1 - 3.2e-41 137.5 72.8 1e-07 32.0 0.7 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68906.1 - 1.9e-27 93.5 68.9 0.00036 21.1 0.6 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM68906.1 - 1.8e-23 82.1 65.3 0.00046 20.5 1.2 8.3 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM68906.1 - 2.1e-15 56.5 38.5 0.017 15.4 0.6 8.5 8 0 0 8 8 8 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM68906.1 - 5e-12 45.5 57.9 0.049 13.7 0.5 8.8 8 1 0 8 8 8 7 C2H2-type zinc finger BolA PF01722.18 KFM68906.1 - 4.8e-08 33.2 11.3 0.15 12.4 0.9 4.7 1 1 3 4 4 4 2 BolA-like protein zf-H2C2_5 PF13909.6 KFM68906.1 - 8.5e-08 31.8 48.3 0.015 15.1 0.8 8.3 8 0 0 8 8 8 4 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM68906.1 - 9.8e-07 28.7 19.2 0.17 11.9 0.1 5.3 3 2 2 5 5 5 4 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM68906.1 - 1.6e-06 28.2 3.0 0.21 11.7 0.1 4.1 1 1 4 5 5 5 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2HC_2 PF13913.6 KFM68906.1 - 2.6e-06 27.2 31.0 0.7 9.9 0.5 8.3 8 0 0 8 8 8 2 zinc-finger of a C2HC-type zf-Dof PF02701.15 KFM68906.1 - 6.5e-06 26.2 21.5 0.45 10.7 3.6 6.7 1 1 5 7 7 7 2 Dof domain, zinc finger DUF2256 PF10013.9 KFM68906.1 - 9.4e-06 25.7 25.5 15 5.8 0.1 8.1 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 KFM68906.1 - 0.0003 20.9 41.3 0.11 12.7 14.9 4.4 1 1 2 3 3 3 2 FYVE zinc finger zf-DBF PF07535.12 KFM68906.1 - 0.003 17.6 37.4 4.4 7.5 0.5 7.8 8 0 0 8 8 8 2 DBF zinc finger C5HCH PF17982.1 KFM68906.1 - 0.0045 17.1 33.7 6.2 7.1 4.1 8.0 6 1 2 8 8 8 0 NSD Cys-His rich domain TRAF6_Z2 PF18048.1 KFM68906.1 - 0.0059 16.7 47.0 0.091 12.9 5.5 7.7 8 0 0 8 8 8 3 TNF receptor-associated factor 6 zinc finger 2 zf-CHCC PF10276.9 KFM68906.1 - 0.013 15.6 14.8 24 5.1 0.1 7.3 8 0 0 8 8 8 0 Zinc-finger domain HNH_5 PF14279.6 KFM68906.1 - 0.015 15.1 40.2 2.4 8.1 2.7 7.5 5 3 0 5 5 5 0 HNH endonuclease zf-C2H2_9 PF16293.5 KFM68906.1 - 0.023 14.5 36.4 3.3 7.6 0.1 7.8 2 1 6 8 8 8 0 C2H2 type zinc-finger (1 copy) DUF3338 PF11819.8 KFM68906.1 - 0.034 14.1 0.0 14 5.7 0.0 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF3338) zf-RRPl_C4 PF17026.5 KFM68906.1 - 0.037 14.1 30.1 2.5 8.3 0.5 4.2 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Complex1_49kDa PF00346.19 KFM68906.1 - 0.12 11.5 0.0 27 3.7 0.0 2.9 1 1 2 4 4 4 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit C1_1 PF00130.22 KFM68906.1 - 0.22 11.4 49.9 9.7 6.2 0.3 8.0 1 1 5 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM68906.1 - 0.24 11.2 23.9 0.77 9.6 0.2 6.1 1 1 7 8 8 8 0 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM68906.1 - 0.31 11.1 33.1 13 5.9 0.1 7.9 4 2 4 8 8 7 0 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM68906.1 - 0.36 10.5 0.2 0.36 10.5 0.2 7.4 4 3 4 8 8 8 0 MYST family zinc finger domain PqqA PF08042.11 KFM68906.1 - 0.44 10.6 4.0 2.9e+02 1.7 0.0 5.3 7 0 0 7 7 6 0 PqqA family zf_UBZ PF18439.1 KFM68906.1 - 0.81 9.3 43.7 6.6 6.4 0.2 8.2 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KFM68906.1 - 0.81 10.5 31.0 9.2 7.1 3.4 4.5 1 1 5 6 6 6 0 zinc-ribbon family zf-RING_UBOX PF13445.6 KFM68906.1 - 5.8 7.0 25.6 47 4.1 0.0 7.5 8 0 0 8 8 8 0 RING-type zinc-finger zf-HIT PF04438.16 KFM68906.1 - 7.3 6.6 40.1 23 5.0 0.3 8.0 8 0 0 8 8 8 0 HIT zinc finger zf-C2H2_2 PF12756.7 KFM68906.1 - 9.3 6.7 56.3 3.2 8.1 0.5 7.8 1 1 6 7 7 6 0 C2H2 type zinc-finger (2 copies) Exo_endo_phos_2 PF14529.6 KFM68908.1 - 1.3e-17 63.8 0.1 1.6e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM68908.1 - 0.0051 16.4 0.1 0.0066 16.0 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DDE_3 PF13358.6 KFM68910.1 - 4.8e-14 52.3 0.1 4.7e-13 49.1 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68910.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM68911.1 - 1.6e-16 60.3 2.6 3.9e-16 59.1 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68911.1 - 7.8e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68912.1 - 2.4e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68912.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Laminin_G_2 PF02210.24 KFM68913.1 - 2.7e-07 31.2 0.0 2.8e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM68913.1 - 1.8e-05 25.0 0.0 1.8e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFM68913.1 - 0.0057 16.8 0.0 0.006 16.7 0.0 1.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 KFM68915.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.5 2 0 0 2 2 2 0 Laminin G domain Laminin_G_2 PF02210.24 KFM68915.1 - 0.045 14.3 0.0 0.068 13.7 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain Laminin_G_1 PF00054.23 KFM68917.1 - 1.5e-09 38.1 0.0 1.8e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFM68917.1 - 3.9e-07 30.7 0.0 4.2e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFM68918.1 - 3.7e-20 72.8 0.3 4.4e-15 56.4 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFM68918.1 - 2e-17 63.6 0.1 1.2e-12 48.1 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 KFM68918.1 - 0.028 14.6 0.0 0.091 12.9 0.0 1.7 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily ING PF12998.7 KFM68919.1 - 0.0039 17.8 7.3 0.072 13.7 7.3 3.0 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding CcdA PF07362.12 KFM68919.1 - 0.0066 16.9 0.1 0.0066 16.9 0.1 2.3 3 0 0 3 3 3 1 Post-segregation antitoxin CcdA Laminin_II PF06009.12 KFM68919.1 - 0.0068 16.4 3.0 0.0068 16.4 3.0 4.0 3 1 1 4 4 4 2 Laminin Domain II DUF1664 PF07889.12 KFM68919.1 - 0.94 9.5 22.5 0.31 11.1 2.1 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 KFM68919.1 - 1.1 8.5 6.8 3.9 6.6 2.0 2.3 1 1 1 2 2 2 0 TMPIT-like protein Laminin_B PF00052.18 KFM68921.1 - 3.2e-23 82.1 0.0 3.9e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_EGF PF00053.24 KFM68921.1 - 4.2e-20 71.6 56.1 7.4e-08 32.4 13.5 4.2 4 0 0 4 4 4 4 Laminin EGF domain RecR PF02132.15 KFM68921.1 - 1.8 8.2 10.5 0.86 9.2 0.9 3.0 2 0 0 2 2 2 0 RecR protein DUF4282 PF14110.6 KFM68922.1 - 8.1 7.3 9.9 60 4.5 9.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) Laminin_EGF PF00053.24 KFM68923.1 - 2.8e-21 75.4 22.2 3.6e-12 46.2 9.6 2.1 2 0 0 2 2 2 2 Laminin EGF domain EGF_2 PF07974.13 KFM68923.1 - 0.35 11.3 33.9 0.14 12.5 5.2 4.1 3 1 1 4 4 4 0 EGF-like domain Stress-antifung PF01657.17 KFM68923.1 - 3.9 8.2 13.1 2 9.1 2.4 2.2 1 1 1 2 2 2 0 Salt stress response/antifungal Sre PF03125.18 KFM68924.1 - 0.017 14.3 3.6 0.019 14.2 3.6 1.0 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Laminin_N PF00055.17 KFM68927.1 - 9.1e-56 189.1 0.0 1.1e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) HTH_Tnp_Tc3_2 PF01498.18 KFM68928.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68928.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease BRO1 PF03097.18 KFM68931.1 - 5.4e-89 298.7 0.1 6.1e-89 298.5 0.1 1.0 1 0 0 1 1 1 1 BRO1-like domain BRO1 PF03097.18 KFM68932.1 - 7.6e-23 80.9 0.0 8.1e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KFM68933.1 - 9.3e-10 38.3 1.9 1e-09 38.2 1.9 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Muted PF14942.6 KFM68933.1 - 0.002 18.5 2.0 0.0024 18.2 2.0 1.1 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein MRPL52 PF18699.1 KFM68933.1 - 0.17 12.1 6.9 0.52 10.5 2.1 2.0 1 1 1 2 2 2 0 Mitoribosomal protein mL52 ALIX_LYPXL_bnd PF13949.6 KFM68934.1 - 4.7e-13 49.1 6.7 4.8e-13 49.1 6.7 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV ALIX_LYPXL_bnd PF13949.6 KFM68935.1 - 8.7e-06 25.2 0.1 1.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Y_phosphatase PF00102.27 KFM68936.1 - 2.1e-59 201.0 0.4 2.8e-59 200.5 0.1 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM68936.1 - 2.7e-06 27.2 0.0 5.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFM68936.1 - 0.0099 16.0 0.0 0.024 14.7 0.0 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFM68936.1 - 0.049 13.6 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PDGF PF00341.17 KFM68937.1 - 9.2e-09 35.5 4.4 1.3e-08 35.0 4.4 1.2 1 0 0 1 1 1 1 PDGF/VEGF domain p47_phox_C PF08944.11 KFM68937.1 - 0.024 14.1 0.5 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain PDGF PF00341.17 KFM68938.1 - 1.1e-07 32.1 3.2 1.1e-07 32.1 3.2 1.7 2 0 0 2 2 2 1 PDGF/VEGF domain Amidase PF01425.21 KFM68941.1 - 0.00069 18.7 0.0 0.00074 18.6 0.0 1.1 1 0 0 1 1 1 1 Amidase HemX PF04375.14 KFM68942.1 - 7e-05 22.3 2.2 7.3e-05 22.2 2.2 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3450 PF11932.8 KFM68942.1 - 0.0008 18.8 3.8 0.0009 18.6 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) FapA PF03961.13 KFM68942.1 - 0.0043 15.7 0.5 0.0043 15.7 0.5 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A LPP PF04728.13 KFM68942.1 - 0.0045 17.3 2.8 0.016 15.6 0.9 2.3 1 1 1 2 2 2 1 Lipoprotein leucine-zipper ADIP PF11559.8 KFM68942.1 - 0.0069 16.5 5.0 0.0077 16.3 5.0 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Shisa PF13908.6 KFM68942.1 - 0.0077 16.5 2.1 0.0083 16.4 2.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4446 PF14584.6 KFM68942.1 - 0.015 15.3 0.7 0.026 14.5 0.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) CENP-K PF11802.8 KFM68942.1 - 0.017 14.7 1.7 0.018 14.7 1.7 1.0 1 0 0 1 1 1 0 Centromere-associated protein K Nsp1_C PF05064.13 KFM68942.1 - 0.025 14.4 1.4 0.039 13.7 1.4 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF1664 PF07889.12 KFM68942.1 - 0.063 13.3 1.3 0.087 12.9 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 KFM68942.1 - 0.068 13.6 2.5 0.088 13.3 2.5 1.1 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Noelin-1 PF12308.8 KFM68942.1 - 0.12 12.4 4.8 0.16 12.0 4.8 1.2 1 0 0 1 1 1 0 Neurogenesis glycoprotein YabA PF06156.13 KFM68942.1 - 0.14 12.8 3.0 0.19 12.4 3.0 1.2 1 0 0 1 1 1 0 Initiation control protein YabA YojJ PF10372.9 KFM68942.1 - 0.17 12.0 2.8 0.64 10.1 0.4 2.1 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus XhlA PF10779.9 KFM68942.1 - 0.29 11.4 4.9 0.72 10.1 2.5 2.3 1 1 1 2 2 2 0 Haemolysin XhlA FUSC PF04632.12 KFM68942.1 - 3.6 6.0 5.8 1.9 6.9 4.2 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family HTH_Tnp_Tc3_2 PF01498.18 KFM68943.1 - 2.5e-16 59.7 2.8 6.3e-16 58.4 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM68943.1 - 1.3e-13 51.0 0.0 2.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68943.1 - 3.3e-07 30.0 1.6 7.7e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68943.1 - 0.0031 17.3 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68943.1 - 2.8 8.6 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68944.1 - 5.2e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68944.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68944.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68944.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68944.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain TIL PF01826.17 KFM68945.1 - 2.3e-09 37.4 42.5 1.8e-07 31.3 18.9 2.2 2 0 0 2 2 2 2 Trypsin Inhibitor like cysteine rich domain 3HCDH PF00725.22 KFM68946.1 - 1.7e-19 70.2 0.0 1.9e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain BMP2K_C PF15282.6 KFM68947.1 - 0.006 16.5 22.4 0.084 12.7 0.6 5.3 4 2 1 5 5 5 4 BMP-2-inducible protein kinase C-terminus Pkinase PF00069.25 KFM68949.1 - 1.1e-40 139.6 0.0 1.6e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM68949.1 - 7.9e-20 71.2 0.0 1.2e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM68949.1 - 4.9e-08 32.6 0.0 2.1e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFM68949.1 - 0.0029 16.4 0.1 0.0048 15.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM68949.1 - 0.013 14.5 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFM68949.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PMD PF10536.9 KFM68949.1 - 0.16 11.0 0.9 0.26 10.4 0.1 1.6 2 0 0 2 2 2 0 Plant mobile domain Kdo PF06293.14 KFM68949.1 - 0.24 10.7 0.2 0.52 9.6 0.1 1.5 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPRY PF00622.28 KFM68950.1 - 1.9e-13 50.6 0.1 1.5e-05 25.1 0.0 3.0 2 0 0 2 2 2 2 SPRY domain PHD PF00628.29 KFM68950.1 - 1.6e-05 24.7 8.7 3.9e-05 23.4 8.7 1.7 1 0 0 1 1 1 1 PHD-finger LAP1C PF05609.12 KFM68950.1 - 0.22 10.6 9.4 0.38 9.8 9.4 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GRA6 PF05084.13 KFM68950.1 - 1.4 8.8 8.4 2.3 8.1 8.4 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) PARG_cat PF05028.14 KFM68951.1 - 6.2e-126 420.2 0.3 6.7e-82 275.5 0.2 2.1 2 0 0 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) HTH_Tnp_Tc3_2 PF01498.18 KFM68951.1 - 4.9e-10 39.5 1.0 1e-09 38.5 1.0 1.6 1 0 0 1 1 1 1 Transposase MAM PF00629.23 KFM68954.1 - 0 2333.0 104.1 3.3e-37 127.9 0.1 28.6 28 1 0 28 28 28 28 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 KFM68954.1 - 3e-51 171.3 150.5 1.5e-08 34.7 6.5 9.9 9 0 0 9 9 9 9 Low-density lipoprotein receptor domain class A Hen1_Lam_C PF18441.1 KFM68954.1 - 0.087 12.7 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain RRM_1 PF00076.22 KFM68955.1 - 0.097 12.5 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRAM PF02893.20 KFM68956.1 - 2.4e-18 66.0 0.0 4.3e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Inv-AAD PF18785.1 KFM68957.1 - 0.12 12.2 1.0 0.13 12.1 1.0 1.1 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase DUF2107 PF09880.9 KFM68960.1 - 0.013 15.6 0.8 0.02 15.0 0.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) Vac14_Fig4_bd PF11916.8 KFM68961.1 - 7.1e-76 253.8 11.6 1.7e-75 252.6 11.6 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KFM68961.1 - 5.8e-45 151.8 0.5 6.9e-41 138.8 0.0 4.2 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KFM68961.1 - 3.9e-11 42.2 1.9 0.00066 19.7 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KFM68961.1 - 1.3e-07 31.8 2.5 1.1 9.3 0.0 4.3 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFM68961.1 - 1.2e-06 28.9 0.4 0.0057 17.1 0.0 3.1 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.6 KFM68961.1 - 8.2e-05 22.9 0.1 2.7 8.4 0.0 4.2 5 0 0 5 5 4 1 HEAT repeats TyeA PF09059.10 KFM68961.1 - 0.0071 16.4 0.3 4.3 7.5 0.1 3.2 2 0 0 2 2 2 1 TyeA RTP1_C1 PF10363.9 KFM68961.1 - 0.018 15.2 3.3 0.76 10.0 0.0 3.9 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KFM68961.1 - 0.023 14.7 0.0 1.7 8.8 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KFM68961.1 - 0.077 13.3 0.1 0.8 10.1 0.1 2.7 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain RasGEF_N_2 PF14663.6 KFM68961.1 - 0.8 10.1 6.7 3.3 8.2 0.0 4.3 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MARVEL PF01284.23 KFM68962.1 - 1.1e-05 25.5 5.1 1.3e-05 25.2 5.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain Ndr PF03096.14 KFM68963.1 - 7e-100 333.4 0.0 9.6e-100 332.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 KFM68963.1 - 3.8e-07 30.0 0.5 1.3e-06 28.3 0.0 1.9 2 1 1 3 3 3 1 alpha/beta hydrolase fold Aminotran_1_2 PF00155.21 KFM68964.1 - 5.1e-39 134.5 0.0 5.7e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-CCHC_4 PF14392.6 KFM68965.1 - 0.07 12.9 15.3 0.089 12.5 2.0 2.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC PF00098.23 KFM68965.1 - 0.14 12.3 2.4 0.14 12.3 2.4 3.8 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_6 PF15288.6 KFM68965.1 - 0.24 11.3 14.4 2 8.3 2.9 3.3 3 0 0 3 3 3 0 Zinc knuckle CLIP1_ZNF PF16641.5 KFM68965.1 - 3.5 7.6 6.5 27 4.8 1.2 3.0 3 1 0 3 3 3 0 CLIP1 zinc knuckle Dimer_Tnp_hAT PF05699.14 KFM68966.1 - 1e-08 34.8 0.3 3.7e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Baculo_LEF-11 PF06385.12 KFM68966.1 - 0.3 11.6 2.6 20 5.8 0.1 3.2 1 1 1 2 2 2 0 Baculovirus LEF-11 protein HTH_Tnp_Tc3_2 PF01498.18 KFM68968.1 - 5.4e-16 58.6 2.2 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68968.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68968.1 - 1.5e-07 31.1 1.1 5.6e-07 29.2 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68968.1 - 0.0017 18.1 0.6 0.005 16.6 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68968.1 - 0.0085 16.2 0.5 0.027 14.6 0.5 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM68968.1 - 2.4 8.9 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain VHP PF02209.19 KFM68970.1 - 5.8e-17 61.5 7.3 1.1e-16 60.5 1.2 2.8 3 0 0 3 3 3 2 Villin headpiece domain AbLIM_anchor PF16182.5 KFM68970.1 - 1.4e-11 44.9 7.3 2e-10 41.1 7.3 2.3 1 1 0 1 1 1 1 Putative adherens-junction anchoring region of AbLIM LIM PF00412.22 KFM68970.1 - 3.3e-08 33.6 6.6 5.6e-07 29.7 2.1 2.6 2 1 0 2 2 2 2 LIM domain ANAPC4_WD40 PF12894.7 KFM68971.1 - 3.4e-11 43.3 1.2 1.5e-05 25.2 0.1 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM68971.1 - 1.4e-10 41.6 19.4 8.1e-05 23.3 0.1 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFM68971.1 - 5.2e-05 22.4 0.7 0.13 11.2 0.0 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFM68971.1 - 0.0015 18.0 0.6 0.014 14.7 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain WD40_3 PF15911.5 KFM68971.1 - 0.02 14.9 0.2 11 6.2 0.0 4.4 4 1 0 4 4 4 0 WD domain, G-beta repeat zf-H2C2_2 PF13465.6 KFM68973.1 - 3e-48 160.2 61.1 4.8e-09 36.2 2.0 8.2 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM68973.1 - 7.7e-35 117.4 63.6 2.7e-06 27.5 1.9 7.3 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM68973.1 - 3.3e-27 92.8 56.9 0.00017 22.1 1.0 7.4 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 KFM68973.1 - 5.6e-24 83.8 53.9 0.00012 22.3 1.1 7.4 7 0 0 7 7 7 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM68973.1 - 1.7e-13 50.5 38.7 0.033 14.5 0.1 7.6 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM68973.1 - 8.7e-12 44.6 41.6 0.00017 21.3 0.3 7.0 7 0 0 7 7 7 5 zinc-finger C2H2-type BolA PF01722.18 KFM68973.1 - 3.2e-11 43.3 12.3 0.00046 20.4 0.7 4.8 1 1 3 5 5 5 4 BolA-like protein zf-C2H2_6 PF13912.6 KFM68973.1 - 3.1e-07 30.2 44.9 0.15 12.1 0.5 7.7 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM68973.1 - 1.4e-06 28.0 46.5 0.04 13.7 0.2 7.5 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM68973.1 - 2.2e-06 27.4 26.9 0.5 10.3 0.4 7.3 7 0 0 7 7 7 2 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM68973.1 - 2.4e-06 27.5 23.1 0.72 9.9 1.0 7.4 4 4 4 8 8 8 2 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM68973.1 - 1.2e-05 25.0 31.4 0.43 10.5 0.4 6.9 2 1 5 7 7 7 3 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM68973.1 - 7.2e-05 23.5 25.1 0.16 12.7 1.7 4.1 1 1 2 4 4 4 2 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM68973.1 - 0.00028 21.0 29.8 0.14 12.3 6.1 3.9 1 1 4 5 5 5 4 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM68973.1 - 0.00032 20.8 22.3 6.7 6.9 0.2 7.1 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_1 PF00130.22 KFM68973.1 - 0.002 18.0 35.3 0.086 12.7 2.3 6.1 2 1 4 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Tox-HNH-HHH PF15637.6 KFM68973.1 - 0.0029 17.7 3.7 3.3 7.9 0.2 3.3 1 1 2 3 3 3 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-DBF PF07535.12 KFM68973.1 - 0.0048 17.0 35.9 3.5 7.8 0.4 7.3 7 0 0 7 7 7 1 DBF zinc finger Zn_ribbon_SprT PF17283.2 KFM68973.1 - 0.005 16.7 14.4 0.24 11.3 0.3 5.4 5 2 1 6 6 6 1 SprT-like zinc ribbon domain zf-FPG_IleRS PF06827.14 KFM68973.1 - 0.018 14.9 19.5 11 6.0 0.0 7.3 7 1 0 7 7 7 0 Zinc finger found in FPG and IleRS Baculo_IE-1 PF05290.11 KFM68973.1 - 0.031 14.2 22.5 5.7 6.9 5.4 5.7 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) Zf_RING PF16744.5 KFM68973.1 - 0.033 14.3 31.5 8.1 6.6 1.6 6.9 1 1 4 5 5 5 0 KIAA1045 RING finger GAGA PF09237.11 KFM68973.1 - 0.042 13.6 11.7 12 5.7 0.0 5.2 2 1 4 6 6 6 0 GAGA factor FYDLN_acid PF09538.10 KFM68973.1 - 0.053 14.2 12.3 2 9.2 0.0 5.4 1 1 6 7 7 7 0 Protein of unknown function (FYDLN_acid) zf-C2H2_2 PF12756.7 KFM68973.1 - 0.058 13.7 53.9 4.1 7.8 1.3 7.0 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zinc-ribbons_6 PF07191.12 KFM68973.1 - 0.062 13.3 26.9 9 6.4 3.1 5.7 1 1 4 5 5 5 0 zinc-ribbons C1_4 PF07975.12 KFM68973.1 - 0.097 12.9 31.4 0.12 12.7 3.0 5.1 2 2 2 5 5 5 0 TFIIH C1-like domain DUF2039 PF10217.9 KFM68973.1 - 0.14 12.5 29.3 0.42 11.0 5.8 3.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2039) zf-RING_UBOX PF13445.6 KFM68973.1 - 0.16 12.0 9.6 36 4.5 0.0 6.1 7 0 0 7 7 7 0 RING-type zinc-finger zf-Dof PF02701.15 KFM68973.1 - 0.17 12.1 19.5 2.8 8.1 1.1 5.3 1 1 4 5 5 5 0 Dof domain, zinc finger ADK_lid PF05191.14 KFM68973.1 - 0.19 11.7 28.8 8.2 6.5 2.5 5.9 2 2 5 7 7 7 0 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM68973.1 - 0.34 10.6 36.5 1.5 8.5 0.4 6.9 2 2 5 7 7 7 0 MYST family zinc finger domain FYVE PF01363.21 KFM68973.1 - 4 7.6 36.2 1.5 9.0 10.2 4.4 1 1 4 5 5 5 0 FYVE zinc finger CxC5 PF18718.1 KFM68973.1 - 4.3 7.4 16.0 3.3 7.8 1.5 3.4 1 1 2 3 3 3 0 CxC5 like cysteine cluster associated with KDZ transposases zf_C2H2_ZHX PF18387.1 KFM68973.1 - 9.5 6.0 36.2 0.21 11.3 2.1 4.5 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain LRR_1 PF00560.33 KFM68974.1 - 0.00052 20.2 13.0 2.1 9.2 0.0 5.0 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.7 KFM68974.1 - 0.0061 16.9 10.4 0.83 10.2 0.3 4.4 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM68974.1 - 0.37 10.9 11.5 2.1 8.6 0.2 4.9 5 0 0 5 5 5 0 Leucine Rich repeat THAP PF05485.12 KFM68976.1 - 2.9e-12 47.3 0.5 6.5e-12 46.2 0.1 1.7 2 0 0 2 2 2 1 THAP domain HHA PF05321.11 KFM68976.1 - 0.071 13.4 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Haemolysin expression modulating protein DUF2180 PF09947.9 KFM68976.1 - 0.082 12.9 0.7 0.25 11.3 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) Sec20 PF03908.13 KFM68977.1 - 2.5e-07 30.5 0.2 2.9e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Sec20 APG17 PF04108.12 KFM68977.1 - 0.066 12.3 0.0 0.078 12.1 0.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 HTH_Tnp_Tc3_2 PF01498.18 KFM68978.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68978.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68978.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68978.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68978.1 - 2.4 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68979.1 - 2.3e-16 59.8 2.2 6.4e-16 58.4 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68979.1 - 1.5e-13 50.7 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68979.1 - 3.3e-07 30.0 1.6 7.8e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68979.1 - 0.003 17.3 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68979.1 - 3.1 8.5 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68980.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68980.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68981.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68981.1 - 8.3e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68982.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68982.1 - 8.4e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease 7TM_GPCR_Srw PF10324.9 KFM68983.1 - 8.5e-42 143.5 16.2 1.1e-41 143.2 16.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KFM68983.1 - 1.4e-16 60.7 16.3 1.8e-16 60.2 16.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM68983.1 - 1.9e-09 37.5 16.7 3.5e-09 36.7 16.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx HTH_Tnp_Tc3_2 PF01498.18 KFM68984.1 - 3.4e-16 59.2 3.0 6.3e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68984.1 - 9.4e-14 51.4 0.0 2.6e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68984.1 - 3.1e-07 30.0 1.6 7.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68984.1 - 0.0029 17.4 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68984.1 - 2.9 8.6 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM68985.1 - 2.3e-16 59.8 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM68985.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SWIM PF04434.17 KFM68986.1 - 0.028 14.1 9.9 0.053 13.2 8.8 2.1 2 0 0 2 2 2 0 SWIM zinc finger Baculo_p74_N PF08404.10 KFM68986.1 - 0.043 12.9 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Ku_PK_bind PF08785.11 KFM68988.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Ku C terminal domain like HTH_Tnp_Tc3_2 PF01498.18 KFM68989.1 - 4.7e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM68989.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM68989.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM68989.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM68989.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM68990.1 - 5.4e-16 58.7 0.1 5.8e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM68990.1 - 7.2e-16 58.2 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM68990.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM68990.1 - 0.0025 17.6 0.1 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM68990.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM68990.1 - 0.034 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix I-set PF07679.16 KFM68991.1 - 8.3e-32 109.1 0.0 6.8e-16 58.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM68991.1 - 1.2e-28 99.5 0.0 4.7e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM68991.1 - 4e-17 62.3 0.0 1.3e-09 38.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain fn3 PF00041.21 KFM68991.1 - 3.5e-16 59.3 0.1 4.5e-15 55.8 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III domain ig PF00047.25 KFM68991.1 - 1.1e-15 57.6 0.0 3.9e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM68991.1 - 1.9e-12 47.3 0.1 6.3e-05 23.1 0.0 4.0 2 2 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM68991.1 - 8.7e-06 25.7 0.0 0.05 13.7 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM68991.1 - 0.0065 17.0 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 KFM68991.1 - 0.036 14.1 0.0 6.9 6.8 0.0 2.7 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFM68991.1 - 0.14 12.4 0.0 2.6 8.3 0.0 2.4 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 fn3 PF00041.21 KFM68992.1 - 4.5e-16 59.0 0.2 3.3e-08 33.7 0.1 3.1 3 0 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM68992.1 - 0.0021 18.6 0.1 0.0021 18.6 0.1 2.9 3 1 1 4 4 4 1 Purple acid Phosphatase, N-terminal domain Shisa PF13908.6 KFM68992.1 - 0.021 15.1 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 KFM68992.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 KFM68992.1 - 0.09 12.2 5.1 0.16 11.4 5.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MIP PF00230.20 KFM68993.1 - 2.5e-41 141.9 7.9 3.2e-41 141.5 7.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein 7tm_1 PF00001.21 KFM68994.1 - 1.6e-12 47.3 12.1 1.7e-12 47.2 12.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KFM68995.1 - 1.5e-06 27.8 0.4 2.2e-06 27.2 0.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tetraspanin PF00335.20 KFM68996.1 - 6.1e-43 147.2 7.6 7.3e-43 146.9 7.6 1.0 1 0 0 1 1 1 1 Tetraspanin family CDCA PF18484.1 KFM68996.1 - 0.0059 16.5 0.1 0.013 15.4 0.1 1.6 2 0 0 2 2 2 1 Cadmium carbonic anhydrase repeat DUF4477 PF14780.6 KFM68997.1 - 4.2e-13 49.4 0.3 4.7e-13 49.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Peptidase_M1 PF01433.20 KFM68999.1 - 2.7e-41 141.5 3.6 3.3e-41 141.2 3.6 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain DUF4364 PF14277.6 KFM68999.1 - 0.0092 15.7 0.0 0.031 14.0 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4364) ERAP1_C PF11838.8 KFM69000.1 - 3.6e-77 260.0 0.6 5e-77 259.5 0.6 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFM69000.1 - 5e-43 147.2 1.0 2.2e-42 145.1 0.3 2.3 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFM69000.1 - 7.1e-14 52.4 0.0 1.5e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Cys_Met_Meta_PP PF01053.20 KFM69001.1 - 3.1e-73 246.5 0.1 3.5e-73 246.4 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AA_permease_2 PF13520.6 KFM69002.1 - 8.2e-17 61.1 6.1 8.9e-17 61.0 6.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM69002.1 - 1.9e-08 33.3 7.5 2.2e-08 33.2 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 KFM69002.1 - 0.0062 15.6 3.8 0.0077 15.3 3.8 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 KFM69002.1 - 0.074 11.7 3.9 0.094 11.4 3.9 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein UPF0220 PF05255.11 KFM69002.1 - 0.09 12.3 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) HTH_Tnp_Tc3_2 PF01498.18 KFM69003.1 - 5e-16 58.7 4.2 5.4e-16 58.6 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM69003.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69003.1 - 1.8e-07 30.8 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69003.1 - 0.0025 17.6 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69003.1 - 1.9 9.2 15.6 0.12 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain GRAM PF02893.20 KFM69004.1 - 9e-22 77.1 0.3 2e-21 76.0 0.3 1.5 1 0 0 1 1 1 1 GRAM domain DUF4227 PF14004.6 KFM69004.1 - 0.27 11.2 2.5 0.75 9.8 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) HTH_Tnp_Tc3_2 PF01498.18 KFM69006.1 - 9.7e-19 67.4 3.8 1.3e-18 67.0 2.1 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69006.1 - 1.2e-14 54.3 0.0 1.5e-13 50.8 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM69006.1 - 3.9e-07 30.6 2.0 8.1e-07 29.6 2.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain RRM_7 PF16367.5 KFM69006.1 - 1e-05 25.6 0.0 3.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 KFM69006.1 - 0.0008 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MarR_2 PF12802.7 KFM69006.1 - 0.0013 18.6 0.4 0.011 15.6 0.0 2.4 1 1 1 2 2 2 1 MarR family HTH_29 PF13551.6 KFM69006.1 - 0.0044 17.0 0.2 0.046 13.7 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 KFM69006.1 - 0.0059 16.6 0.4 0.044 13.8 0.0 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM69006.1 - 0.006 16.7 0.8 0.62 10.2 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM69006.1 - 0.084 13.0 0.2 17 5.6 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM69006.1 - 0.1 12.4 1.3 2.5 8.0 0.0 2.7 2 1 0 2 2 2 0 Homeodomain-like domain RRM_1 PF00076.22 KFM69007.1 - 6.2e-12 45.2 0.0 2.1e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4371 PF14291.6 KFM69007.1 - 2.9e-05 23.8 0.1 7.3e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Lebercilin PF15619.6 KFM69007.1 - 0.017 14.8 2.5 0.032 13.9 2.5 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Csm2_III-A PF03750.13 KFM69007.1 - 0.16 12.8 0.6 12 6.7 0.0 3.2 3 0 0 3 3 3 0 Csm2 Type III-A Mito_carr PF00153.27 KFM69008.1 - 1.3e-49 166.1 3.6 5.7e-18 64.6 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4244 PF14029.6 KFM69008.1 - 1.1 8.7 5.6 13 5.3 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4244) RVT_1 PF00078.27 KFM69009.1 - 3.2e-46 157.6 0.0 4.6e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMA7 PF09072.10 KFM69010.1 - 2.7e-21 76.2 17.6 3e-21 76.0 17.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 RRM_1 PF00076.22 KFM69011.1 - 1.3e-17 63.4 0.0 1.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med11 PF10280.9 KFM69012.1 - 7.3e-14 52.4 4.2 9e-14 52.1 4.2 1.2 1 0 0 1 1 1 1 Mediator complex protein DUF4806 PF16064.5 KFM69012.1 - 0.017 15.4 0.8 0.057 13.7 0.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4806) HTH_WhiA PF02650.14 KFM69012.1 - 0.075 13.4 1.5 0.16 12.3 0.2 2.0 2 0 0 2 2 2 0 WhiA C-terminal HTH domain 4HB_MCP_1 PF12729.7 KFM69012.1 - 0.18 11.3 2.3 0.13 11.8 0.5 1.6 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction FapA PF03961.13 KFM69012.1 - 9.3 4.7 7.2 2.1 6.8 0.9 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A Dimer_Tnp_hAT PF05699.14 KFM69013.1 - 1.5e-11 43.9 0.0 3.5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KFM69013.1 - 4.4e-07 29.9 1.2 0.0062 16.4 0.6 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Propep_M14 PF02244.16 KFM69013.1 - 1.2 9.6 4.7 4.3 7.8 0.7 3.2 4 0 0 4 4 4 0 Carboxypeptidase activation peptide DDE_3 PF13358.6 KFM69014.1 - 3e-13 49.8 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PRiA4_ORF3 PF07929.11 KFM69014.1 - 0.057 13.1 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein DDE_3 PF13358.6 KFM69015.1 - 5.3e-16 58.7 0.1 6e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69015.1 - 7.5e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69015.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69015.1 - 0.0026 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69015.1 - 0.016 15.3 0.1 0.066 13.3 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69015.1 - 0.034 14.2 2.6 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM69016.1 - 4.3e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69016.1 - 1.1e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69016.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69016.1 - 0.0025 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69016.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Cytochrom_C PF00034.21 KFM69018.1 - 4.6e-14 53.3 0.0 6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFM69018.1 - 1.7e-07 31.5 2.1 7.2e-07 29.4 2.1 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFM69018.1 - 0.00075 19.2 0.1 0.0024 17.6 0.1 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain Pox_P4A PF03395.14 KFM69019.1 - 0.018 12.7 0.2 0.018 12.7 0.2 1.0 1 0 0 1 1 1 0 Poxvirus P4A protein z-alpha PF02295.17 KFM69019.1 - 0.041 13.9 0.0 0.052 13.6 0.0 1.3 1 1 0 1 1 1 0 Adenosine deaminase z-alpha domain Zip PF02535.22 KFM69021.1 - 1e-78 264.9 11.8 1e-78 264.9 11.8 2.5 3 0 0 3 3 3 1 ZIP Zinc transporter ZIP4_domain PF18292.1 KFM69021.1 - 0.023 14.7 0.3 0.061 13.2 0.3 1.8 1 0 0 1 1 1 0 Zinc transporter ZIP4 domain FAM220 PF15487.6 KFM69021.1 - 0.65 9.6 5.9 1.6 8.3 5.9 1.6 1 0 0 1 1 1 0 FAM220 family SirB PF04247.12 KFM69021.1 - 1.2 9.3 6.6 4.8 7.3 0.8 2.6 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB MTABC_N PF16185.5 KFM69022.1 - 5.6e-31 107.9 2.8 6.2e-31 107.8 2.8 1.0 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region Phage_Coat_Gp8 PF05371.12 KFM69022.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Phage major coat protein, Gp8 DUF3285 PF11688.8 KFM69022.1 - 0.22 11.5 2.4 0.39 10.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) DnaJ_C PF01556.18 KFM69023.1 - 1.1e-40 139.2 0.1 1.4e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFM69023.1 - 6.2e-26 90.3 1.9 1.2e-25 89.4 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain Reprolysin PF01421.19 KFM69025.1 - 4.8e-28 98.4 0.1 7.3e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFM69025.1 - 1.4e-21 76.7 10.0 1.4e-21 76.7 10.0 2.8 3 0 0 3 3 3 1 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFM69025.1 - 2e-18 67.3 1.0 3.2e-18 66.6 1.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFM69025.1 - 7.6e-13 49.1 0.2 1.2e-12 48.5 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFM69025.1 - 2.7e-11 43.7 1.3 7.1e-11 42.4 1.3 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.19 KFM69025.1 - 8.9e-08 32.2 3.2 8.9e-08 32.2 3.2 3.4 4 1 0 4 4 3 1 Thrombospondin type 1 domain Reprolysin_4 PF13583.6 KFM69025.1 - 2.1e-07 30.8 0.1 3.1e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4575 PF15143.6 KFM69025.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4575) Peptidase_M10 PF00413.24 KFM69025.1 - 0.064 13.1 0.9 0.15 11.9 0.4 1.4 1 1 0 1 1 1 0 Matrixin DUF4953 PF16313.5 KFM69025.1 - 0.2 10.8 0.2 0.35 10.0 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 KFM69025.1 - 0.32 9.9 1.4 0.49 9.3 1.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Tetraspanin PF00335.20 KFM69026.1 - 1.2e-25 90.6 0.6 1.6e-25 90.1 0.6 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2244 PF10003.9 KFM69026.1 - 6.9 6.4 6.9 30 4.3 0.9 2.9 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) Ectatomin PF06457.11 KFM69027.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Ectatomin Ribosomal_S17_N PF16205.5 KFM69029.1 - 4.1e-34 116.8 1.6 6.4e-34 116.2 1.6 1.3 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KFM69029.1 - 3.6e-08 33.4 1.3 6.2e-08 32.6 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 PRF PF06875.11 KFM69029.1 - 0.044 13.2 0.1 0.058 12.8 0.1 1.1 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF CD36 PF01130.21 KFM69030.1 - 5.8e-135 450.4 1.4 6.8e-135 450.2 1.4 1.0 1 0 0 1 1 1 1 CD36 family DUF5337 PF17272.2 KFM69030.1 - 0.045 13.6 0.2 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Prokineticin PF06607.11 KFM69031.1 - 1.5e-06 28.5 4.2 2.8e-06 27.5 4.2 1.5 1 1 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM69031.1 - 4.9e-05 23.8 10.6 0.0006 20.4 10.6 2.1 1 1 0 1 1 1 1 MIT-like atracotoxin family DX PF01666.17 KFM69031.1 - 0.0088 16.5 0.3 0.0088 16.5 0.3 2.1 1 1 1 2 2 2 1 DX module EB PF01683.18 KFM69032.1 - 2.5e-18 66.1 32.4 1e-06 28.9 1.1 4.1 1 1 3 4 4 4 4 EB module cEGF PF12662.7 KFM69032.1 - 0.00064 19.6 12.8 0.001 18.9 0.2 3.7 3 0 0 3 3 3 2 Complement Clr-like EGF-like TIL PF01826.17 KFM69032.1 - 0.0075 16.5 38.8 0.19 12.0 3.3 4.4 3 1 1 4 4 4 4 Trypsin Inhibitor like cysteine rich domain Ldl_recept_a PF00057.18 KFM69033.1 - 3e-20 72.1 41.6 8.7e-12 45.1 8.6 4.0 3 1 1 4 4 4 3 Low-density lipoprotein receptor domain class A ADAM_CR PF08516.12 KFM69033.1 - 2.2 8.7 23.0 1.1 9.7 4.6 2.9 1 1 1 2 2 2 0 ADAM cysteine-rich Arfaptin PF06456.13 KFM69034.1 - 3.1e-27 95.6 1.0 3.1e-27 95.6 1.0 2.1 1 1 1 2 2 2 1 Arfaptin-like domain ICA69 PF04629.14 KFM69034.1 - 2.8e-14 54.1 17.3 5e-14 53.2 17.3 1.4 1 0 0 1 1 1 1 Islet cell autoantigen ICA69, C-terminal domain tRNA_NucTran2_2 PF13735.6 KFM69034.1 - 2.1 8.3 5.5 8.7 6.3 0.1 2.3 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Arfaptin PF06456.13 KFM69035.1 - 7e-26 91.2 0.9 7.7e-26 91.1 0.9 1.0 1 0 0 1 1 1 1 Arfaptin-like domain CRISPR_Cas9_WED PF18061.1 KFM69035.1 - 0.12 12.5 0.1 0.32 11.1 0.1 1.6 1 1 0 1 1 1 0 CRISPR-Cas9 WED domain zf-C2H2 PF00096.26 KFM69036.1 - 4.6e-18 64.6 43.8 3e-05 24.2 1.7 5.9 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69036.1 - 2e-08 34.3 36.3 0.02 15.7 1.9 6.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFM69036.1 - 3.1e-08 33.8 18.3 0.00011 22.4 3.1 4.1 3 0 0 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFM69036.1 - 3.9e-07 30.2 32.9 0.079 13.3 3.8 5.7 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFM69036.1 - 0.00028 21.2 4.3 0.00028 21.2 4.3 6.4 7 0 0 7 7 7 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM69036.1 - 0.00029 20.5 6.7 0.00029 20.5 6.7 4.3 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFM69036.1 - 0.0051 17.2 39.1 0.74 10.3 0.6 5.8 5 0 0 5 5 5 4 Zinc-finger of C2H2 type GAGA PF09237.11 KFM69036.1 - 1 9.2 5.8 1.3 8.9 0.3 3.3 3 0 0 3 3 3 0 GAGA factor zf-BED PF02892.15 KFM69036.1 - 2.8 8.0 20.4 0.16 12.0 0.5 4.0 3 1 1 4 4 4 0 BED zinc finger zf-C2H2_jaz PF12171.8 KFM69037.1 - 8.1e-14 51.5 0.6 1.5e-06 28.3 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFM69037.1 - 5.6e-13 48.6 1.4 1.1e-05 25.6 0.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69037.1 - 1.4e-12 47.3 1.8 1.2e-05 25.7 0.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM69037.1 - 6.9e-12 45.3 4.2 3e-05 24.3 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM69037.1 - 1.7e-09 37.4 2.3 0.00054 19.9 0.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM69037.1 - 5.6e-07 29.7 0.4 0.00016 21.9 0.0 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2HC_2 PF13913.6 KFM69037.1 - 5.8e-05 22.9 0.2 0.00043 20.1 0.0 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFM69037.1 - 0.00012 21.8 3.5 0.012 15.4 0.2 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-BED PF02892.15 KFM69037.1 - 0.00033 20.6 1.3 0.029 14.4 0.1 2.2 1 1 1 2 2 2 1 BED zinc finger zf-Di19 PF05605.12 KFM69037.1 - 0.0012 19.0 1.1 0.0033 17.7 1.1 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 KFM69037.1 - 0.0022 18.4 1.8 0.015 15.7 0.4 2.1 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFM69037.1 - 0.0044 17.3 1.6 0.054 13.8 0.2 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM69037.1 - 0.0082 15.7 0.0 3 7.5 0.0 2.1 2 0 0 2 2 2 2 MYST family zinc finger domain zf_UBZ PF18439.1 KFM69037.1 - 0.0094 15.5 0.6 2 8.1 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 KFM69037.1 - 0.012 16.1 0.4 0.066 13.7 0.0 2.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Actin_micro PF17003.5 KFM69037.1 - 0.012 14.8 0.5 1.5 7.9 0.0 2.0 1 1 1 2 2 2 0 Putative actin-like family zf-C2H2_9 PF16293.5 KFM69037.1 - 0.068 13.0 0.9 3 7.8 0.0 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFM69037.1 - 0.077 13.1 0.2 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM69037.1 - 0.087 12.9 0.2 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 DBF zinc finger Armet PF10208.9 KFM69038.1 - 1.8e-66 222.5 8.6 2.1e-66 222.3 8.6 1.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding 7tm_1 PF00001.21 KFM69039.1 - 4.9e-25 88.4 6.5 6.2e-25 88.0 6.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM69039.1 - 1e-05 25.4 6.1 1e-05 25.4 6.1 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx HTH_Tnp_Tc3_2 PF01498.18 KFM69040.1 - 1.6e-16 60.3 2.2 2.9e-16 59.5 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69040.1 - 0.00016 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_H PF00075.24 KFM69041.1 - 1.3e-05 25.4 0.1 2.3e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 RNase H CLCA PF08434.11 KFM69042.1 - 1.2e-77 260.8 0.0 1.8e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA PF00092.28 KFM69042.1 - 5.3e-20 72.4 0.0 1.1e-19 71.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFM69042.1 - 1.6e-14 54.5 0.0 3.3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFM69042.1 - 4.4e-08 32.8 0.0 7.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 KFM69042.1 - 0.00013 22.1 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF1194 PF06707.11 KFM69042.1 - 0.00015 21.0 0.1 0.00059 19.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) Sushi PF00084.20 KFM69043.1 - 2.9e-34 117.5 14.8 1.1e-09 38.7 0.1 4.6 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) HRM PF02793.22 KFM69043.1 - 4e-07 30.2 8.2 1.9 8.9 0.1 4.4 4 0 0 4 4 4 4 Hormone receptor domain Borrelia_P83 PF05262.11 KFM69043.1 - 5.1 5.5 39.2 7.5 4.9 39.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein EphA2_TM PF14575.6 KFM69043.1 - 5.2 8.0 0.0 5.2 8.0 0.0 3.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RhoGAP PF00620.27 KFM69044.1 - 6.4e-36 123.5 0.2 8.1e-36 123.1 0.2 1.1 1 0 0 1 1 1 1 RhoGAP domain SH2 PF00017.24 KFM69045.1 - 8.8e-17 61.0 0.3 2.2e-16 59.7 0.1 1.7 2 0 0 2 2 2 1 SH2 domain EF-hand_7 PF13499.6 KFM69046.1 - 4.2e-07 30.3 2.4 0.00043 20.7 0.3 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM69046.1 - 5.9e-07 28.9 5.8 0.00013 21.6 0.5 4.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KFM69046.1 - 0.008 15.7 4.1 0.12 12.0 0.1 3.5 4 0 0 4 4 4 1 EF hand NTR2 PF15458.6 KFM69046.1 - 0.024 14.2 0.2 0.033 13.7 0.2 1.1 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DDE_3 PF13358.6 KFM69047.1 - 5.6e-08 32.7 0.0 8.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_11 PF01531.16 KFM69049.1 - 3.1e-54 184.2 0.0 3.8e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 DUF92 PF01940.16 KFM69050.1 - 8.3e-46 156.3 4.1 8.9e-46 156.2 4.1 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 BTB PF00651.31 KFM69052.1 - 1.8e-12 47.5 0.1 3.2e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFM69053.1 - 1.5e-39 134.7 0.4 6e-27 94.1 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM69053.1 - 0.00026 21.0 1.9 0.03 14.4 0.2 2.9 2 0 0 2 2 2 2 BTB And C-terminal Kelch RT_RNaseH_2 PF17919.1 KFM69055.1 - 1.8e-37 127.4 0.0 2.7e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM69055.1 - 1.4e-32 112.0 0.0 2.3e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase EF-hand_1 PF00036.32 KFM69056.1 - 2.1e-11 42.5 2.8 0.00047 19.5 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFM69056.1 - 4.5e-10 38.6 1.7 0.00019 21.1 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFM69056.1 - 1.7e-09 38.0 3.9 0.003 18.0 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFM69056.1 - 1.1e-07 31.0 0.7 0.0042 16.5 0.0 3.5 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 KFM69056.1 - 4.3e-05 23.6 0.2 0.0012 18.9 0.0 2.8 3 0 0 3 3 3 1 Dockerin type I domain EF-hand_8 PF13833.6 KFM69056.1 - 0.0015 18.4 4.4 1.3 9.0 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM69056.1 - 0.011 16.1 0.7 17 5.8 0.2 3.0 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 KFM69056.1 - 0.031 14.2 3.9 1.7 8.5 0.1 2.7 1 1 2 3 3 3 0 Caleosin related protein EF-hand_4 PF12763.7 KFM69056.1 - 0.033 14.2 0.9 5.5 7.0 0.2 2.7 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand HTH_Tnp_Tc3_2 PF01498.18 KFM69057.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69057.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69058.1 - 5.5e-16 58.6 3.9 6e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69058.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69058.1 - 6.4e-06 25.8 1.0 2.5e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69058.1 - 0.0069 16.2 0.4 0.02 14.7 0.4 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM69059.1 - 1.8e-15 56.9 6.5 1.8e-15 56.9 6.5 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69059.1 - 9.5e-14 51.4 0.1 1.1e-12 48.0 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM69059.1 - 0.00089 19.8 1.5 0.00089 19.8 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69059.1 - 0.0032 17.2 0.1 0.14 12.0 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69059.1 - 0.02 15.0 0.1 0.078 13.1 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69059.1 - 0.043 13.9 0.4 0.043 13.9 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM69060.1 - 2e-14 53.6 0.1 2.6e-13 50.0 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69060.1 - 1.1e-10 41.6 1.0 2.8e-10 40.3 1.0 1.7 1 0 0 1 1 1 1 Transposase DUF1917 PF08939.10 KFM69063.1 - 0.0086 16.0 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DUF1917 PF08939.10 KFM69064.1 - 0.00048 20.1 1.3 0.0012 18.8 1.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) MCR_C PF04609.12 KFM69064.1 - 0.04 13.0 0.0 0.083 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C HTH_Tnp_Tc3_2 PF01498.18 KFM69065.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69065.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MMR_HSR1 PF01926.23 KFM69066.1 - 4.6e-13 49.3 0.0 6.5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM69066.1 - 0.00014 21.8 0.0 0.00017 21.5 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KFM69066.1 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFM69066.1 - 0.065 13.3 0.4 1.1 9.4 0.3 2.1 1 1 0 2 2 2 0 Dynamin family SRPRB PF09439.10 KFM69066.1 - 0.084 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ank_2 PF12796.7 KFM69067.1 - 4.5e-09 36.8 0.0 7.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM69067.1 - 7.4e-09 35.1 0.1 0.00032 20.9 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat BTB PF00651.31 KFM69067.1 - 1.2e-08 35.1 0.1 2e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ank_4 PF13637.6 KFM69067.1 - 2.3e-08 34.4 0.0 4.7e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM69067.1 - 7.2e-07 29.4 0.1 2e-06 27.9 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM69067.1 - 1.7e-05 25.1 0.0 0.0035 17.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat PDGF PF00341.17 KFM69070.1 - 4.6e-12 46.1 4.5 4.6e-12 46.1 4.5 2.5 1 1 1 2 2 2 1 PDGF/VEGF domain CXCXC PF03128.14 KFM69070.1 - 0.011 16.1 12.2 0.035 14.5 4.1 5.1 4 0 0 4 4 4 0 CXCXC repeat AF-4 PF05110.13 KFM69071.1 - 9.8e-35 120.0 12.5 1.6e-34 119.3 12.5 1.3 1 1 0 1 1 1 1 AF-4 proto-oncoprotein Bestrophin PF01062.21 KFM69073.1 - 1.1e-35 123.5 3.4 1.2e-35 123.3 3.4 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel NGF PF00243.18 KFM69075.1 - 2.7e-07 30.8 1.7 5.6e-07 29.8 1.5 1.7 1 1 0 1 1 1 1 Nerve growth factor family HLH PF00010.26 KFM69076.1 - 2.7e-12 46.5 4.8 4.8e-12 45.6 4.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Basic PF01586.16 KFM69076.1 - 1.2e-08 36.0 5.5 1.2e-08 36.0 5.5 3.1 2 1 1 3 3 3 1 Myogenic Basic domain Myf5 PF12232.8 KFM69076.1 - 1.8e-05 25.4 0.1 1.8e-05 25.4 0.1 3.1 2 1 1 3 3 3 1 Myogenic determination factor 5 BSP_II PF05432.11 KFM69076.1 - 0.027 14.2 0.2 0.027 14.2 0.2 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PI3_PI4_kinase PF00454.27 KFM69077.1 - 1.5e-58 198.6 0.1 4.9e-58 196.9 0.1 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFM69077.1 - 1.8e-51 174.2 3.4 3.5e-51 173.2 3.4 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_p85B PF02192.16 KFM69077.1 - 1.1e-30 105.2 0.2 2.6e-30 104.0 0.2 1.7 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_C2 PF00792.24 KFM69077.1 - 2.3e-21 76.2 0.1 5e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 KFM69077.1 - 6e-21 74.6 0.3 2.5e-20 72.6 0.1 2.2 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 KFM69077.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DDE_Tnp_1_7 PF13843.6 KFM69078.1 - 7e-59 199.9 0.1 8.4e-59 199.6 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM69078.1 - 3.1 8.7 8.8 4.6 8.1 5.9 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon I-set PF07679.16 KFM69081.1 - 4.7e-15 55.4 0.0 5.4e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM69081.1 - 8e-10 39.2 0.0 1.3e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM69081.1 - 8.5e-08 32.3 0.1 1.6e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM69081.1 - 8.9e-08 32.3 0.6 2.9e-07 30.6 0.6 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM69081.1 - 1.2e-05 25.5 0.6 3.1e-05 24.2 0.6 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM69081.1 - 0.0027 17.7 0.1 0.0047 17.0 0.1 1.6 1 1 0 1 1 1 1 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFM69081.1 - 0.0032 17.2 0.6 0.0042 16.8 0.6 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 KFM69081.1 - 0.012 15.1 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain LRR_8 PF13855.6 KFM69082.1 - 1.4e-42 143.3 41.7 2.4e-12 46.4 3.7 6.6 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFM69082.1 - 7.7e-22 77.0 38.8 0.00058 20.2 4.4 7.7 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM69082.1 - 2.4e-13 50.1 0.1 2e-05 24.5 0.0 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM69082.1 - 2.8e-10 40.0 8.1 8.3e-06 25.4 2.4 4.0 2 1 3 5 5 5 2 Leucine-rich repeat LRR_1 PF00560.33 KFM69082.1 - 0.00024 21.2 38.2 1.2 10.0 0.0 10.7 9 3 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 KFM69082.1 - 0.069 13.2 23.6 4.1 7.7 0.0 8.4 11 0 0 11 11 11 0 Leucine Rich repeat FNIP PF05725.12 KFM69082.1 - 0.14 12.4 5.9 0.15 12.3 1.6 3.3 3 2 0 3 3 3 0 FNIP Repeat MULE PF10551.9 KFM69083.1 - 7.7e-19 67.9 0.6 2e-18 66.6 0.6 1.8 1 0 0 1 1 1 1 MULE transposase domain zf-C2H2 PF00096.26 KFM69083.1 - 0.0011 19.3 1.6 0.0011 19.3 1.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69083.1 - 0.0073 17.1 1.3 0.0073 17.1 1.3 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger RusA PF05866.11 KFM69083.1 - 2.2 8.8 5.4 0.59 10.7 0.1 2.7 3 0 0 3 3 3 0 Endodeoxyribonuclease RusA DDE_Tnp_1_7 PF13843.6 KFM69084.1 - 2.6e-93 313.1 4.0 3.1e-93 312.9 4.0 1.1 1 0 0 1 1 1 1 Transposase IS4 TIR PF01582.20 KFM69085.1 - 8.7e-06 25.6 0.1 4e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFM69085.1 - 5.3e-05 23.8 0.0 6.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 TIR domain HTH_Tnp_Tc3_2 PF01498.18 KFM69088.1 - 4.9e-16 58.7 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69088.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69088.1 - 2.2e-07 30.5 1.2 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69088.1 - 0.0026 17.5 0.6 0.0078 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69088.1 - 0.028 14.5 0.4 0.094 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM69088.1 - 2.4 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain zf-CCCH_4 PF18044.1 KFM69089.1 - 0.018 14.8 2.7 0.049 13.4 2.7 1.7 1 1 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFM69089.1 - 0.033 14.7 2.2 0.056 13.9 2.2 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFM69089.1 - 0.038 13.9 5.4 0.51 10.3 5.4 2.2 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM69089.1 - 0.33 11.1 4.8 8 6.7 0.1 2.3 2 0 0 2 2 2 0 Zinc finger domain HTH_Tnp_Tc3_2 PF01498.18 KFM69090.1 - 4.7e-16 58.8 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69090.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69090.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69090.1 - 0.0026 17.5 0.6 0.0076 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69090.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM69091.1 - 2.8e-16 59.6 0.1 3e-15 56.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69091.1 - 8.3e-16 58.0 6.5 1.4e-15 57.3 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69091.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69091.1 - 0.0024 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69091.1 - 0.016 15.3 0.1 0.064 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69091.1 - 0.034 14.1 0.4 0.034 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM69092.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69092.1 - 9.1e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69093.1 - 4.6e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69093.1 - 7.6e-12 45.2 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69093.1 - 1.9e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69093.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69093.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM69094.1 - 2.2e-16 59.9 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69094.1 - 5.4e-13 48.9 0.0 8.7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69095.1 - 5e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69095.1 - 3.1e-11 43.2 0.0 5.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69095.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69095.1 - 0.0027 17.5 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69095.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM69096.1 - 2.1e-16 59.9 2.2 4.7e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69096.1 - 9.8e-14 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2 PF00096.26 KFM69097.1 - 0.00011 22.4 0.1 0.00011 22.4 0.1 2.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69097.1 - 0.00052 20.6 0.3 0.00052 20.6 0.3 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM69097.1 - 0.053 13.8 0.2 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM69097.1 - 0.15 12.1 0.5 0.15 12.1 0.5 2.2 3 0 0 3 3 3 0 C2H2-type zinc finger Nuc_recep-AF1 PF11825.8 KFM69097.1 - 5.3 7.1 13.3 21 5.2 1.1 2.8 1 1 2 3 3 3 0 Nuclear/hormone receptor activator site AF-1 LRR_9 PF14580.6 KFM69098.1 - 4.3e-11 42.6 5.3 1.7e-10 40.7 5.2 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFM69098.1 - 2.3e-05 24.6 20.1 0.0015 18.9 6.8 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM69098.1 - 0.0015 18.2 12.4 0.014 15.2 2.6 3.0 1 1 0 2 2 2 2 Leucine rich repeat DDE_3 PF13358.6 KFM69099.1 - 4.2e-16 59.0 0.1 5.5e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69099.1 - 7.3e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69099.1 - 0.00068 20.2 1.5 0.00068 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69099.1 - 0.0023 17.7 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69099.1 - 0.014 15.5 0.1 0.062 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69099.1 - 0.033 14.2 2.6 0.033 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM69100.1 - 4e-16 59.0 3.5 5.5e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69100.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69100.1 - 1.9e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69100.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69100.1 - 0.025 14.7 0.4 0.088 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM69100.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain L_HMGIC_fpl PF10242.9 KFM69101.1 - 6.1e-22 78.7 0.6 8e-22 78.3 0.6 1.2 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Katanin_con80 PF13925.6 KFM69102.1 - 3.7e-47 160.3 0.5 5.1e-47 159.9 0.5 1.2 1 0 0 1 1 1 1 con80 domain of Katanin Lipase PF00151.19 KFM69103.1 - 6.9e-10 38.7 0.0 7.7e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Lipase MFS_1 PF07690.16 KFM69104.1 - 1.1e-37 129.8 71.0 2.3e-29 102.4 42.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFM69104.1 - 4.1e-05 22.6 28.4 0.057 12.3 0.5 3.9 2 2 0 3 3 3 3 MFS_1 like family BT1 PF03092.16 KFM69104.1 - 0.0041 15.4 7.8 0.075 11.2 0.2 2.4 2 1 0 2 2 2 2 BT1 family UPF0060 PF02694.15 KFM69104.1 - 0.014 15.7 6.9 0.035 14.4 0.4 3.3 3 1 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family FragX_IP PF05994.11 KFM69106.1 - 1.7e-112 377.1 0.1 1.7e-112 377.1 0.1 1.5 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 KFM69106.1 - 0.0013 18.0 0.7 0.0031 16.8 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) TbpB_A PF17484.2 KFM69106.1 - 0.0016 19.2 0.0 0.0049 17.6 0.0 1.8 1 0 0 1 1 1 1 N-Lobe handle Tf-binding protein B Tnp_22_trimer PF17489.2 KFM69106.1 - 0.083 12.9 0.1 0.89 9.6 0.0 2.6 2 0 0 2 2 2 0 L1 transposable element trimerization domain FragX_IP PF05994.11 KFM69107.1 - 4.2e-281 934.8 0.0 4.7e-281 934.7 0.0 1.0 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family WD40 PF00400.32 KFM69109.1 - 3e-25 88.0 1.9 6.3e-05 23.7 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM69109.1 - 4.9e-13 49.2 0.0 0.022 15.1 0.0 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TIMP PF00965.17 KFM69109.1 - 0.035 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase WD40_like PF17005.5 KFM69109.1 - 0.058 12.7 0.0 26 4.0 0.0 3.6 4 0 0 4 4 4 0 WD40-like domain CARM1 PF11531.8 KFM69110.1 - 0.12 12.6 0.4 0.16 12.2 0.4 1.1 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal THAP PF05485.12 KFM69111.1 - 2.8e-07 31.4 0.1 2.8e-07 31.4 0.1 1.0 1 0 0 1 1 1 1 THAP domain HTH_Tnp_Tc3_2 PF01498.18 KFM69112.1 - 2.2e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69112.1 - 5e-13 49.0 0.0 8.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69113.1 - 3.9e-16 59.1 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69113.1 - 1.5e-13 50.7 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69113.1 - 3.2e-07 30.0 1.6 7.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69113.1 - 0.003 17.3 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69113.1 - 0.034 14.3 0.4 0.099 12.8 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM69113.1 - 2.9 8.6 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain OATP PF03137.20 KFM69114.1 - 3e-76 256.9 8.9 3.5e-76 256.6 8.9 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.15 KFM69114.1 - 0.00016 21.7 10.5 0.00034 20.7 10.5 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM69114.1 - 0.0017 18.3 3.8 0.0047 16.9 3.8 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain VMA21 PF09446.10 KFM69114.1 - 0.0038 17.3 1.8 0.006 16.7 0.4 2.1 2 0 0 2 2 2 1 VMA21-like domain MFS_1 PF07690.16 KFM69114.1 - 0.0094 14.9 13.1 0.01 14.8 4.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3533 PF12051.8 KFM69114.1 - 0.1 11.5 3.7 0.19 10.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) MFS_MOT1 PF16983.5 KFM69114.1 - 3.2 8.2 8.3 0.95 9.9 0.3 2.6 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily DDE_3 PF13358.6 KFM69116.1 - 0.00015 21.5 0.0 0.00015 21.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Nbas_N PF15492.6 KFM69118.1 - 1e-72 244.9 0.1 1.3e-72 244.5 0.1 1.1 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 KFM69118.1 - 0.00012 22.3 0.0 0.47 10.8 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Sec39 PF08314.11 KFM69122.1 - 6.2e-13 48.1 0.7 6.2e-13 48.1 0.7 2.6 3 0 0 3 3 3 1 Secretory pathway protein Sec39 DAN PF03045.15 KFM69122.1 - 0.078 13.0 2.2 0.12 12.4 0.7 2.1 2 0 0 2 2 2 0 DAN domain DDE_1 PF03184.19 KFM69123.1 - 3.5e-12 46.3 0.2 3.6e-12 46.3 0.2 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Zip PF02535.22 KFM69124.1 - 2.5e-64 217.6 12.1 3.9e-64 217.0 12.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter S8_pro-domain PF16470.5 KFM69125.1 - 0.00071 20.3 0.0 0.001 19.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase S8 pro-domain SVWC PF15430.6 KFM69126.1 - 2.5e-09 37.2 3.5 2.9e-09 37.0 3.5 1.2 1 0 0 1 1 1 1 Single domain von Willebrand factor type C HTH_Tnp_Tc3_2 PF01498.18 KFM69127.1 - 3.7e-17 62.3 6.1 4.5e-16 58.9 2.2 2.3 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM69127.1 - 9.6e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_22 PF03901.17 KFM69129.1 - 3.4e-18 66.1 6.7 4.2e-18 65.8 6.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_transf_22 PF03901.17 KFM69130.1 - 8.7e-62 209.7 28.8 9.8e-62 209.5 28.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 KFM69130.1 - 5.8e-08 33.1 8.6 5.8e-08 33.1 8.6 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Uma2 PF05685.12 KFM69131.1 - 0.00058 19.4 0.4 0.0013 18.3 0.4 1.5 1 0 0 1 1 1 1 Putative restriction endonuclease NUC153 PF08159.12 KFM69131.1 - 4.4 7.2 12.0 0.43 10.4 0.8 3.7 3 1 1 4 4 4 0 NUC153 domain HTH_24 PF13412.6 KFM69132.1 - 0.00075 19.0 0.0 0.0015 18.0 0.0 1.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r3 PF04539.16 KFM69132.1 - 0.057 13.5 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-70 region 3 SpoIIID PF12116.8 KFM69132.1 - 0.076 13.1 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D DDE_3 PF13358.6 KFM69133.1 - 6.8e-08 32.4 0.0 9.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM69133.1 - 0.00071 20.1 0.9 0.0057 17.2 0.3 2.3 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM69133.1 - 0.0024 17.7 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 MarR family PPO1_DWL PF12142.8 KFM69133.1 - 0.026 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Polyphenol oxidase middle domain HTH_Tnp_Tc3_2 PF01498.18 KFM69133.1 - 0.047 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Transposase PAX PF00292.18 KFM69133.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.7 1 1 1 2 2 2 0 'Paired box' domain HTH_24 PF13412.6 KFM69133.1 - 0.17 11.5 0.1 20 4.9 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Helicase_C PF00271.31 KFM69134.1 - 3e-31 108.0 0.1 2e-30 105.4 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM69134.1 - 2.3e-19 69.8 0.2 5.1e-19 68.7 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KFM69134.1 - 2.1e-07 30.4 0.0 3.6e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_lid_5 PF17865.1 KFM69134.1 - 0.073 13.2 0.0 0.87 9.7 0.0 2.5 3 1 0 3 3 3 0 Midasin AAA lid domain Gly_acyl_tr_C PF08444.10 KFM69134.1 - 0.31 11.3 0.8 5.3 7.4 0.3 2.4 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DEAD PF00270.29 KFM69135.1 - 2.4e-13 50.2 0.2 3.1e-13 49.9 0.2 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase HMG-CoA_red PF00368.18 KFM69136.1 - 2.5e-141 470.9 0.1 3.3e-141 470.5 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KFM69136.1 - 1.1e-14 54.5 4.7 2.5e-14 53.4 4.7 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFM69136.1 - 3e-07 28.9 1.3 4.7e-07 28.3 1.3 1.2 1 0 0 1 1 1 1 Patched family DUF4371 PF14291.6 KFM69137.1 - 2.8e-06 27.2 1.3 3.4e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM69137.1 - 0.059 13.2 0.0 0.19 11.5 0.0 2.0 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region TRC8_N PF13705.6 KFM69138.1 - 2.7e-133 445.5 33.5 3.3e-133 445.2 33.5 1.1 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-C3HC4_2 PF13923.6 KFM69138.1 - 9.5e-09 35.0 10.1 9.5e-09 35.0 10.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM69138.1 - 2e-08 34.4 11.2 4.2e-08 33.4 11.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFM69138.1 - 2.2e-06 27.8 10.2 6.3e-06 26.4 10.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFM69138.1 - 4.5e-06 26.4 6.2 8.6e-06 25.5 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM69138.1 - 4.7e-06 26.4 9.5 4.7e-06 26.4 9.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM69138.1 - 0.00014 21.8 7.6 0.00014 21.8 7.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM69138.1 - 0.00015 21.7 9.8 0.0003 20.7 9.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM69138.1 - 0.00099 18.9 8.5 0.002 17.9 8.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFM69138.1 - 0.0042 16.8 8.1 0.012 15.3 8.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KFM69138.1 - 0.012 15.2 6.3 0.034 13.8 6.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 KFM69138.1 - 0.04 13.6 7.8 0.12 12.0 7.8 1.9 1 1 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 KFM69138.1 - 0.049 13.7 8.4 0.21 11.7 7.7 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KFM69138.1 - 0.13 12.4 4.2 0.46 10.7 4.2 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-HC5HC2H PF13771.6 KFM69138.1 - 0.15 12.3 4.3 0.12 12.7 2.4 1.8 2 0 0 2 2 1 0 PHD-like zinc-binding domain RINGv PF12906.7 KFM69138.1 - 0.35 11.0 8.4 0.74 10.0 8.4 1.6 1 0 0 1 1 1 0 RING-variant domain Zf_RING PF16744.5 KFM69138.1 - 0.84 9.8 4.7 1.8 8.8 4.7 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger Xpo1 PF08389.12 KFM69139.1 - 0.031 14.3 0.6 0.037 14.1 0.6 1.1 1 0 0 1 1 1 0 Exportin 1-like protein HLH PF00010.26 KFM69140.1 - 1e-11 44.6 0.2 1.6e-11 44.0 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SVIP PF15811.5 KFM69140.1 - 0.041 14.3 1.3 0.053 14.0 1.3 1.2 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Sugar_tr PF00083.24 KFM69142.1 - 1.1e-07 31.1 0.0 1.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Pentapeptide_3 PF13576.6 KFM69142.1 - 0.00014 21.9 2.9 0.00045 20.3 2.7 1.9 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 KFM69142.1 - 0.00071 19.7 5.2 0.0028 17.8 5.2 1.9 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KFM69142.1 - 0.014 15.0 0.1 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) MFS_1 PF07690.16 KFM69143.1 - 1e-12 47.7 1.1 1.1e-12 47.6 1.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM69143.1 - 2.4e-06 26.7 0.5 2.5e-06 26.6 0.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KFM69143.1 - 9.4e-05 21.1 0.1 0.0001 21.0 0.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein ADK PF00406.22 KFM69145.1 - 1.7e-51 174.3 0.0 2e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFM69145.1 - 8.7e-39 133.1 0.0 1e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM69145.1 - 5.6e-09 36.6 0.0 7.4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM69145.1 - 2.5e-08 34.2 0.0 3.9e-08 33.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFM69145.1 - 0.0078 16.6 0.2 0.072 13.5 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFM69145.1 - 0.013 15.9 0.5 0.024 15.0 0.1 1.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KFM69145.1 - 0.014 15.0 0.1 0.79 9.4 0.0 2.1 1 1 1 2 2 2 0 Thymidylate kinase Cytidylate_kin PF02224.18 KFM69145.1 - 0.019 14.7 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase NTPase_1 PF03266.15 KFM69145.1 - 0.028 14.3 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase eIF3g PF12353.8 KFM69146.1 - 3.9e-41 140.4 1.7 6.9e-41 139.6 1.7 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KFM69146.1 - 1.3e-18 66.5 0.0 2.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM69146.1 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif CDV3 PF15359.6 KFM69146.1 - 0.0044 17.5 1.6 0.0075 16.7 1.6 1.4 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 Nup35_RRM_2 PF14605.6 KFM69146.1 - 0.036 14.1 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 KFM69146.1 - 0.093 12.8 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 RNA binding domain DUF4743 PF15916.5 KFM69147.1 - 0.0027 17.7 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4743) DDE_Tnp_1_7 PF13843.6 KFM69148.1 - 6.1e-17 61.9 0.3 7.5e-17 61.7 0.3 1.1 1 0 0 1 1 1 1 Transposase IS4 C1_2 PF03107.16 KFM69148.1 - 4.1e-05 23.8 2.9 7.9e-05 22.9 2.9 1.5 1 0 0 1 1 1 1 C1 domain Tnp_zf-ribbon_2 PF13842.6 KFM69148.1 - 0.00062 20.5 10.3 0.0014 19.4 10.3 1.6 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon zf-B_box PF00643.24 KFM69148.1 - 0.22 11.7 4.7 0.34 11.1 4.7 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-HIT PF04438.16 KFM69148.1 - 1.5 8.7 8.5 2.8 7.9 8.5 1.5 1 0 0 1 1 1 0 HIT zinc finger RhoGEF PF00621.20 KFM69150.1 - 1.2e-47 162.5 3.0 2.2e-47 161.7 3.0 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_2 PF07653.17 KFM69150.1 - 3.1e-11 42.8 0.0 8.3e-11 41.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFM69150.1 - 1.8e-10 40.5 0.1 9.2e-10 38.2 0.3 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFM69150.1 - 3.6e-10 39.3 1.4 3e-09 36.3 2.6 2.1 2 0 0 2 2 2 1 SH3 domain PH PF00169.29 KFM69150.1 - 3.6e-09 37.1 0.7 1.1e-08 35.5 0.7 1.8 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFM69150.1 - 0.13 12.1 3.1 0.36 10.6 1.5 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain FCH PF00611.23 KFM69150.1 - 0.15 12.3 0.3 1.9 8.9 0.0 2.7 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain BTB PF00651.31 KFM69151.1 - 3.4e-38 130.3 5.6 2.4e-25 88.9 1.9 2.9 2 1 1 3 3 3 2 BTB/POZ domain MATH PF00917.26 KFM69151.1 - 1.1e-08 35.2 3.8 5.1e-05 23.4 0.0 2.9 3 0 0 3 3 3 2 MATH domain BACK PF07707.15 KFM69151.1 - 0.0087 16.1 2.2 0.071 13.2 0.2 3.4 3 0 0 3 3 3 1 BTB And C-terminal Kelch Glypican PF01153.19 KFM69152.1 - 8.4e-78 262.6 0.2 9.8e-78 262.3 0.2 1.0 1 0 0 1 1 1 1 Glypican DUF999 PF06198.11 KFM69152.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF999) SCA7 PF08313.12 KFM69152.1 - 0.023 14.6 0.1 0.056 13.3 0.1 1.6 1 0 0 1 1 1 0 SCA7, zinc-binding domain GlutR_dimer PF00745.20 KFM69152.1 - 0.026 14.9 0.0 0.11 13.0 0.1 1.8 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Glypican PF01153.19 KFM69153.1 - 1.7e-29 103.2 0.1 2.2e-29 102.7 0.1 1.2 1 1 0 1 1 1 1 Glypican zf-H2C2_2 PF13465.6 KFM69154.1 - 4.3e-103 333.5 101.0 9.1e-09 35.4 0.2 16.0 16 0 0 16 16 16 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69154.1 - 6.6e-72 234.2 132.6 8e-06 26.0 1.3 15.1 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69154.1 - 7e-50 163.4 118.7 0.00065 20.3 0.1 15.1 15 0 0 15 15 15 15 C2H2-type zinc finger zf-met PF12874.7 KFM69154.1 - 4e-46 154.1 123.3 6e-05 23.3 2.0 15.2 15 0 0 15 15 15 15 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM69154.1 - 1.4e-23 82.6 81.3 0.0047 17.2 0.6 15.3 15 0 0 15 15 15 12 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM69154.1 - 7.2e-23 80.1 91.3 0.0015 18.4 0.1 15.3 15 0 0 15 15 15 9 C2H2-type zinc finger BolA PF01722.18 KFM69154.1 - 1.9e-12 47.3 23.0 0.13 12.5 0.3 8.8 2 1 8 10 10 10 5 BolA-like protein zf-H2C2_5 PF13909.6 KFM69154.1 - 1.9e-12 46.7 78.1 0.13 12.1 0.4 15.4 15 0 0 15 15 15 7 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM69154.1 - 2.6e-08 33.8 64.0 0.11 12.6 0.1 13.0 10 5 4 14 14 14 3 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM69154.1 - 3.1e-06 26.9 75.3 0.22 11.4 0.2 14.1 3 2 12 15 15 15 6 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM69154.1 - 5.4e-06 26.1 35.0 1.1 9.2 0.2 11.3 2 2 12 14 14 14 1 GAGA factor zf-RRPl_C4 PF17026.5 KFM69154.1 - 2.1e-05 24.5 65.6 0.2 11.7 6.9 6.8 1 1 7 8 8 8 7 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 KFM69154.1 - 5.3e-05 23.0 80.3 1.5 8.8 3.1 11.6 5 5 5 10 10 10 5 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KFM69154.1 - 7.2e-05 22.7 53.7 3.8 7.6 1.4 8.6 2 1 2 4 4 3 2 Double zinc ribbon ADK_lid PF05191.14 KFM69154.1 - 0.00067 19.6 62.6 0.42 10.6 1.5 10.0 7 2 3 10 10 10 5 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM69154.1 - 0.0025 17.9 59.3 1.6 8.9 0.3 14.4 15 0 0 15 15 15 2 Uncharacterized protein conserved in bacteria (DUF2256) Chal_sti_synt_N PF00195.19 KFM69154.1 - 0.041 13.3 0.5 0.041 13.3 0.5 4.9 1 1 3 5 5 5 0 Chalcone and stilbene synthases, N-terminal domain DUF2441 PF10386.9 KFM69154.1 - 0.044 13.8 0.0 7.2 6.6 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2441) zf-CHCC PF10276.9 KFM69154.1 - 0.077 13.1 24.0 9.2 6.4 0.0 11.0 14 0 0 14 14 14 0 Zinc-finger domain zf-DBF PF07535.12 KFM69154.1 - 0.11 12.6 65.1 11 6.2 0.1 13.2 14 0 0 14 14 14 0 DBF zinc finger zinc_ribbon_15 PF17032.5 KFM69154.1 - 1.5 9.7 64.0 1.3 9.9 1.3 7.9 1 1 7 9 9 9 0 zinc-ribbon family VirE1 PF12189.8 KFM69154.1 - 2.4 8.4 14.7 5 7.3 0.1 6.8 5 2 4 9 9 9 0 Single-strand DNA-binding protein DUF3268 PF11672.8 KFM69154.1 - 4.1 7.8 38.7 1 9.7 0.3 6.5 6 1 1 7 7 7 0 zinc-finger-containing domain NADH_u_ox_C PF12853.7 KFM69156.1 - 0.0053 16.7 0.5 1.4 9.0 0.1 2.1 1 1 1 2 2 2 2 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DDE_3 PF13358.6 KFM69157.1 - 1.8e-10 40.8 0.0 2.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69159.1 - 2.4e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69159.1 - 9.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69160.1 - 4.4e-16 58.9 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69160.1 - 1.3e-13 50.9 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69160.1 - 2e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69160.1 - 0.0026 17.5 0.6 0.0076 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69160.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM69161.1 - 4.6e-16 58.8 3.5 6e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69161.1 - 2.5e-13 50.0 0.0 5.8e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69161.1 - 2.1e-07 30.6 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69161.1 - 0.0027 17.4 0.6 0.008 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_48 PF17906.1 KFM69162.1 - 7.1e-05 22.8 0.1 0.0001 22.3 0.1 1.2 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM69162.1 - 0.0036 17.9 0.0 0.007 17.0 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain Ins_allergen_rp PF06757.13 KFM69162.1 - 0.16 12.0 0.0 15 5.5 0.0 2.1 1 1 1 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification PheRS_DBD3 PF18553.1 KFM69162.1 - 0.18 12.1 0.0 0.6 10.4 0.0 1.8 2 0 0 2 2 2 0 PheRS DNA binding domain 3 DUF525 PF04379.14 KFM69163.1 - 7.7e-25 87.0 0.0 1.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 ApaG domain F-box-like PF12937.7 KFM69163.1 - 5.9e-09 35.7 0.2 1.4e-08 34.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM69163.1 - 1e-08 34.8 0.2 2e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain SMI1_KNR4 PF09346.10 KFM69163.1 - 8.4e-05 23.0 0.0 0.00026 21.4 0.0 1.9 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) F-box_4 PF15966.5 KFM69163.1 - 0.055 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 F-box RRM_1 PF00076.22 KFM69164.1 - 1.3e-34 117.8 0.0 1.2e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM69164.1 - 1.4e-05 25.1 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM69164.1 - 0.00013 21.9 0.0 0.041 13.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 KFM69164.1 - 0.00084 19.3 0.0 0.078 13.0 0.0 2.7 2 0 0 2 2 2 1 RNA binding domain PHM7_cyt PF14703.6 KFM69164.1 - 0.0065 16.7 0.1 4.1 7.6 0.0 3.3 2 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 KFM69165.1 - 4.4e-20 71.3 0.1 7.3e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFM69165.1 - 0.0042 17.1 0.0 0.0091 16.0 0.0 1.5 1 1 0 1 1 1 1 RNA binding domain DUF4817 PF16087.5 KFM69168.1 - 1.4e-08 34.4 2.1 2.2e-08 33.7 2.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_48 PF17906.1 KFM69168.1 - 0.0014 18.7 5.0 0.0028 17.7 5.0 1.5 2 0 0 2 2 2 1 HTH domain in Mos1 transposase MogR_DNAbind PF12181.8 KFM69169.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) MADF_DNA_bdg PF10545.9 KFM69170.1 - 7.7e-15 55.0 0.4 8.6e-15 54.8 0.4 1.0 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 KFM69170.1 - 0.0013 18.7 0.3 0.0017 18.4 0.3 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KFM69170.1 - 0.0057 16.8 0.4 0.012 15.8 0.4 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFM69170.1 - 0.037 14.4 0.1 0.046 14.1 0.1 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 KFM69171.1 - 9e-09 35.2 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM69171.1 - 0.0018 17.9 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein RNase_H PF00075.24 KFM69173.1 - 0.00018 21.7 0.0 0.0002 21.6 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM69173.1 - 0.02 14.7 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like Sec63 PF02889.16 KFM69174.1 - 9e-172 569.0 5.2 1.2e-89 299.9 1.3 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KFM69174.1 - 2.8e-51 173.8 0.1 1.2e-26 93.6 0.1 3.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KFM69174.1 - 3.3e-36 123.8 0.3 1.7e-35 121.6 0.3 2.3 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KFM69174.1 - 4.5e-26 91.9 0.1 9.1e-14 51.8 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFM69174.1 - 3.5e-13 49.9 0.7 3.5e-06 27.3 0.0 4.0 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFM69174.1 - 1.3e-07 32.0 0.2 0.049 13.9 0.1 3.9 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KFM69174.1 - 5e-07 29.6 0.0 0.065 13.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KFM69174.1 - 0.00018 21.9 0.0 0.062 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFM69174.1 - 0.0011 18.1 0.0 2.4 7.2 0.0 3.5 3 0 0 3 3 3 2 Type II/IV secretion system protein PhoH PF02562.16 KFM69174.1 - 0.0053 16.2 0.0 0.52 9.7 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 KFM69174.1 - 0.0061 16.4 2.5 0.32 10.7 0.0 3.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KFM69174.1 - 0.12 12.1 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein UvrD-helicase PF00580.21 KFM69174.1 - 1.3 8.5 8.4 12 5.3 0.0 3.9 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain DDE_3 PF13358.6 KFM69175.1 - 1.6e-12 47.4 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69176.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69176.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69176.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69176.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69176.1 - 2.1 9.0 15.6 0.12 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Kinesin PF00225.23 KFM69180.1 - 2.4e-20 72.7 0.1 2.8e-20 72.5 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM69180.1 - 2.1e-16 60.2 0.0 2.5e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding ResIII PF04851.15 KFM69180.1 - 0.15 12.1 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 KFM69180.1 - 0.21 10.6 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Kinesin PF00225.23 KFM69181.1 - 1.5e-49 168.8 0.4 1.5e-49 168.8 0.4 2.1 2 0 0 2 2 2 1 Kinesin motor domain Fmp27_WPPW PF10359.9 KFM69181.1 - 0.0054 15.6 2.0 0.0078 15.1 2.0 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Spore_GerAC PF05504.11 KFM69181.1 - 0.0063 16.7 0.2 0.0063 16.7 0.2 1.7 2 0 0 2 2 2 1 Spore germination B3/ GerAC like, C-terminal Cnn_1N PF07989.11 KFM69181.1 - 0.023 14.9 2.2 0.023 14.9 2.2 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 KFM69181.1 - 0.037 12.9 9.6 0.11 11.3 9.6 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF484 PF04340.12 KFM69181.1 - 0.045 13.4 0.4 0.072 12.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF484 FlxA PF14282.6 KFM69181.1 - 0.046 13.7 10.2 0.31 11.1 2.3 2.4 1 1 1 2 2 2 0 FlxA-like protein DUF885 PF05960.11 KFM69181.1 - 0.05 13.3 0.2 0.066 12.8 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) IKBKB_SDD PF18397.1 KFM69181.1 - 0.082 12.2 4.8 0.12 11.7 4.8 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain GAS PF13851.6 KFM69181.1 - 0.14 11.4 9.4 0.74 9.1 6.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 KFM69181.1 - 0.21 11.9 9.5 0.3 11.4 3.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 KFM69181.1 - 0.37 11.3 8.3 0.51 10.9 7.5 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 KFM69181.1 - 0.87 10.1 12.8 0.25 11.8 5.8 2.6 1 1 1 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 KFM69181.1 - 1.2 9.8 5.0 14 6.4 0.2 2.8 1 1 1 2 2 2 0 SlyX DUF16 PF01519.16 KFM69181.1 - 2.5 8.6 8.6 17 5.9 3.6 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF5320 PF17253.2 KFM69181.1 - 2.7 9.1 5.2 23 6.2 0.0 2.7 2 1 1 3 3 2 0 Family of unknown function (DUF5320) DHR10 PF18595.1 KFM69181.1 - 2.7 8.0 11.0 7.3 6.7 5.1 2.7 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain THOC7 PF05615.13 KFM69181.1 - 2.8 8.2 9.2 31 4.9 3.9 3.0 1 1 1 2 2 2 0 Tho complex subunit 7 YabA PF06156.13 KFM69181.1 - 2.8 8.6 9.0 3.9 8.2 5.1 2.6 2 1 1 3 3 3 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 KFM69181.1 - 3 8.2 8.4 0.98 9.7 4.1 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4140 PF13600.6 KFM69181.1 - 3.2 8.3 6.1 9.1 6.8 0.1 2.7 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF2408 PF10303.9 KFM69181.1 - 3.4 8.2 7.1 35 5.0 7.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TMPIT PF07851.13 KFM69181.1 - 4.3 6.5 5.9 5 6.3 0.8 2.0 1 1 1 2 2 2 0 TMPIT-like protein Virul_fac_BrkB PF03631.15 KFM69182.1 - 0.067 12.8 0.0 0.086 12.4 0.0 1.0 1 0 0 1 1 1 0 Virulence factor BrkB UxuA PF03786.13 KFM69182.1 - 0.17 10.7 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) HALZ PF02183.18 KFM69183.1 - 1.1e-05 25.5 13.5 0.00041 20.5 2.3 3.5 2 2 2 4 4 4 2 Homeobox associated leucine zipper HAP1_N PF04849.13 KFM69183.1 - 0.00025 20.4 21.3 0.0006 19.1 4.4 2.0 1 1 1 2 2 2 2 HAP1 N-terminal conserved region ZapB PF06005.12 KFM69183.1 - 0.00051 20.4 24.9 0.0044 17.4 9.8 3.1 1 1 2 3 3 3 1 Cell division protein ZapB bZIP_2 PF07716.15 KFM69183.1 - 0.00065 19.7 3.3 0.00065 19.7 3.3 3.9 2 1 2 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM69183.1 - 0.0034 17.4 4.3 0.0034 17.4 4.3 3.3 1 1 2 4 4 4 1 bZIP transcription factor Spc7 PF08317.11 KFM69183.1 - 0.0037 16.2 17.2 0.0042 16.0 17.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TSC22 PF01166.18 KFM69183.1 - 0.0077 16.5 21.6 0.2 12.0 1.7 3.9 2 1 2 4 4 4 3 TSC-22/dip/bun family GAS PF13851.6 KFM69183.1 - 0.018 14.4 20.6 0.06 12.7 20.6 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Taxilin PF09728.9 KFM69183.1 - 0.021 14.0 19.3 0.036 13.2 19.3 1.4 1 1 0 1 1 1 0 Myosin-like coiled-coil protein JIP_LZII PF16471.5 KFM69183.1 - 0.022 14.9 15.8 0.15 12.3 2.5 3.0 3 1 1 4 4 3 0 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 KFM69183.1 - 0.032 14.3 21.2 0.016 15.2 18.0 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 KFM69183.1 - 0.089 12.6 21.3 0.42 10.4 5.3 3.4 2 1 3 5 5 5 0 Septum formation initiator K-box PF01486.17 KFM69183.1 - 0.096 12.9 17.4 0.43 10.8 2.7 3.4 2 2 0 2 2 2 0 K-box region Macoilin PF09726.9 KFM69183.1 - 0.11 11.0 10.8 0.12 10.9 10.8 1.1 1 0 0 1 1 1 0 Macoilin family MbeD_MobD PF04899.12 KFM69183.1 - 0.19 11.9 5.7 0.31 11.2 3.8 2.3 1 1 2 3 3 3 0 MbeD/MobD like MCC-bdg_PDZ PF10506.9 KFM69183.1 - 0.24 11.5 14.0 2.9 8.0 0.1 2.6 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome GIT1_C PF12205.8 KFM69183.1 - 0.26 11.4 7.1 0.35 11.0 7.1 1.2 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term YabA PF06156.13 KFM69183.1 - 0.27 11.9 16.5 0.43 11.2 4.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 KFM69183.1 - 0.27 11.3 19.8 0.54 10.3 9.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 KFM69183.1 - 0.28 11.2 20.8 1.1 9.3 4.5 2.4 1 1 1 2 2 2 0 FlxA-like protein Atg14 PF10186.9 KFM69183.1 - 0.28 10.2 13.9 0.36 9.9 13.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3347 PF11827.8 KFM69183.1 - 0.31 11.2 8.0 0.59 10.3 5.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3347) LPP PF04728.13 KFM69183.1 - 0.38 11.2 7.1 0.2 12.1 1.0 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Jnk-SapK_ap_N PF09744.9 KFM69183.1 - 0.51 10.6 20.0 0.53 10.5 19.2 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KFM69183.1 - 1.1 9.3 8.5 1 9.4 5.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 KFM69183.1 - 1.6 7.5 13.8 0.55 9.0 9.4 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain MctB PF11382.8 KFM69183.1 - 1.7 8.3 6.4 3 7.4 1.3 2.1 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB UPF0242 PF06785.11 KFM69183.1 - 1.9 8.6 20.7 3.5 7.7 18.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Shugoshin_N PF07558.11 KFM69183.1 - 4.6 7.2 15.3 0.16 11.9 0.7 3.8 4 0 0 4 4 3 0 Shugoshin N-terminal coiled-coil region Cep57_CLD_2 PF14197.6 KFM69183.1 - 4.9 7.3 17.8 6.7 6.9 8.4 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 V_ATPase_I PF01496.19 KFM69183.1 - 5.7 4.7 11.0 6 4.7 11.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Swi5 PF07061.11 KFM69183.1 - 6.6 6.9 19.5 2.8 8.1 3.1 3.0 2 1 1 3 3 3 0 Swi5 XhlA PF10779.9 KFM69183.1 - 7.1 6.9 8.8 0.35 11.1 1.7 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF3450 PF11932.8 KFM69183.1 - 9.2 5.5 16.5 4.1 6.6 8.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TDH PF03347.13 KFM69184.1 - 0.023 14.3 0.1 0.64 9.6 0.0 2.2 2 0 0 2 2 2 0 Vibrio thermostable direct hemolysin NTS PF15447.6 KFM69184.1 - 0.19 12.3 1.6 0.33 11.5 0.1 2.2 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 SlyX PF04102.12 KFM69184.1 - 4 8.1 7.2 4.2 8.1 0.0 3.1 2 1 1 3 3 3 0 SlyX Neur_chan_memb PF02932.16 KFM69185.1 - 4.3e-22 79.3 3.6 7.4e-22 78.6 3.6 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ig_2 PF13895.6 KFM69186.1 - 2.8e-12 46.8 0.2 7.3e-05 23.0 0.1 3.8 3 2 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM69186.1 - 4.6e-11 42.6 0.1 0.00047 20.2 0.0 2.9 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM69186.1 - 2.2e-09 37.8 2.2 0.00035 21.1 0.1 3.9 3 2 1 4 4 4 2 Immunoglobulin domain ig PF00047.25 KFM69186.1 - 0.00039 20.5 0.1 13 6.0 0.0 4.0 4 0 0 4 4 4 1 Immunoglobulin domain C1-set PF07654.15 KFM69186.1 - 0.0012 19.1 0.0 1.1 9.7 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin C1-set domain I-set PF07679.16 KFM69186.1 - 0.002 18.2 0.2 0.32 11.1 0.0 3.6 3 2 0 3 3 3 1 Immunoglobulin I-set domain V-set PF07686.17 KFM69186.1 - 0.004 17.3 0.4 1.8 8.8 0.0 3.7 3 2 1 4 4 4 1 Immunoglobulin V-set domain SNX17_FERM_C PF18116.1 KFM69190.1 - 8.4e-39 131.9 0.0 1.6e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain PX PF00787.24 KFM69190.1 - 6.6e-16 58.3 0.0 6e-14 52.0 0.0 2.3 2 0 0 2 2 2 1 PX domain FERM_M PF00373.18 KFM69190.1 - 0.0078 16.6 0.0 0.035 14.5 0.0 2.2 1 1 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFM69190.1 - 0.092 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 FERM N-terminal domain AbbA_antirepres PF14156.6 KFM69190.1 - 0.17 11.8 2.6 12 5.9 1.1 2.5 2 0 0 2 2 2 0 Antirepressor AbbA EGF PF00008.27 KFM69191.1 - 1.7e-08 34.6 22.0 4.9e-05 23.5 7.9 2.4 2 0 0 2 2 2 2 EGF-like domain EGF_CA PF07645.15 KFM69191.1 - 3.7e-06 27.0 20.9 1.5e-05 25.1 3.1 2.3 2 0 0 2 2 2 2 Calcium-binding EGF domain hEGF PF12661.7 KFM69191.1 - 0.00066 20.2 17.5 0.14 12.8 4.2 2.7 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_2 PF07974.13 KFM69191.1 - 0.017 15.5 23.5 0.053 13.9 12.0 2.5 2 0 0 2 2 2 0 EGF-like domain EGF_MSP1_1 PF12946.7 KFM69191.1 - 0.028 14.5 4.3 0.028 14.5 4.3 2.7 2 1 0 2 2 2 0 MSP1 EGF domain 1 FXa_inhibition PF14670.6 KFM69191.1 - 0.05 13.9 19.6 0.48 10.8 3.1 2.4 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KFM69191.1 - 0.064 13.6 24.1 0.76 10.1 4.6 2.8 2 1 1 3 3 3 0 Pvs28 EGF domain EGF_3 PF12947.7 KFM69191.1 - 0.55 10.5 18.9 2.1 8.6 4.0 2.5 2 0 0 2 2 2 0 EGF domain AAA PF00004.29 KFM69193.1 - 2.4e-17 63.6 0.0 5e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM69193.1 - 0.00023 21.4 0.1 0.0024 18.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFM69193.1 - 0.0014 18.4 0.1 0.028 14.1 0.0 2.7 2 1 1 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFM69193.1 - 0.0016 18.8 0.0 0.0059 17.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_16 PF13191.6 KFM69193.1 - 0.0042 17.5 0.0 0.083 13.3 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFM69193.1 - 0.0072 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFM69193.1 - 0.011 15.8 0.0 0.035 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM69193.1 - 0.015 15.8 0.0 0.034 14.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF3637 PF12337.8 KFM69193.1 - 0.016 15.5 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) AAA_7 PF12775.7 KFM69193.1 - 0.02 14.4 0.4 0.07 12.6 0.0 2.1 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFM69193.1 - 0.087 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFM69193.1 - 0.12 11.8 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KFM69194.1 - 5.1e-44 149.9 0.0 6.4e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM69194.1 - 7.1e-07 29.3 0.0 1e-05 25.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFM69194.1 - 5.5e-05 23.4 0.0 7.9e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFM69194.1 - 6.1e-05 22.8 0.0 0.00037 20.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM69194.1 - 0.00016 22.1 0.1 0.0044 17.4 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 KFM69194.1 - 0.0013 19.2 0.1 0.012 16.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFM69194.1 - 0.0032 16.9 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFM69194.1 - 0.0043 16.6 0.0 0.021 14.4 0.0 2.1 3 0 0 3 3 3 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KFM69194.1 - 0.0043 17.4 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.15 KFM69194.1 - 0.0062 16.5 0.0 0.018 15.0 0.0 1.7 1 1 1 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 KFM69194.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KFM69194.1 - 0.029 14.4 0.0 0.046 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM69194.1 - 0.034 14.4 0.0 2.7 8.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KFM69194.1 - 0.048 13.4 0.0 0.82 9.3 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 KFM69194.1 - 0.052 13.7 0.0 0.066 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFM69194.1 - 0.057 13.3 0.0 0.086 12.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KFM69194.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KFM69194.1 - 0.1 12.7 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain E2 PF08199.11 KFM69195.1 - 0.065 13.2 3.0 0.12 12.3 3.0 1.5 1 0 0 1 1 1 0 Bacteriophage E2-like protein DUF2616 PF11077.8 KFM69195.1 - 0.08 12.7 4.2 0.089 12.5 4.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2616) BetaGal_dom4_5 PF13364.6 KFM69196.1 - 0.018 15.6 0.0 0.14 12.8 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Utp12 PF04003.12 KFM69197.1 - 6.7e-13 48.9 3.6 6.7e-13 48.9 3.6 1.6 2 0 0 2 2 2 1 Dip2/Utp12 Family MgtE_N PF03448.17 KFM69197.1 - 0.0011 19.6 0.9 0.0057 17.2 0.3 2.0 2 0 0 2 2 2 1 MgtE intracellular N domain Hrs_helical PF12210.8 KFM69197.1 - 0.021 15.3 5.0 1.9 9.1 0.3 2.9 1 1 2 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate PucR PF07905.11 KFM69197.1 - 0.071 13.4 0.1 0.096 13.0 0.1 1.3 1 1 0 1 1 1 0 Purine catabolism regulatory protein-like family DUF445 PF04286.12 KFM69197.1 - 0.08 12.7 3.2 0.099 12.4 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CorA PF01544.18 KFM69197.1 - 0.086 12.1 2.9 0.17 11.2 2.7 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SLED PF12140.8 KFM69197.1 - 0.098 13.2 0.4 0.16 12.5 0.3 1.4 1 1 0 1 1 1 0 SLED domain ECF_trnsprt PF12822.7 KFM69200.1 - 0.34 11.0 11.8 0.98 9.5 11.9 1.8 1 1 0 1 1 1 0 ECF transporter, substrate-specific component DUF3341 PF11821.8 KFM69200.1 - 3 7.4 6.7 6 6.5 2.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3341) Guanylate_cyc PF00211.20 KFM69201.1 - 2.6e-55 186.9 0.0 3.1e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain zf-H2C2_2 PF13465.6 KFM69202.1 - 7.8e-40 133.6 50.3 2.3e-09 37.3 1.2 7.1 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69202.1 - 2.7e-24 84.2 62.1 2.9e-05 24.3 1.6 6.9 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69202.1 - 5e-18 64.2 55.9 0.0018 19.0 2.3 6.5 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM69202.1 - 4.5e-13 49.1 35.4 0.00013 22.1 0.6 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM69202.1 - 1e-12 48.0 45.7 0.00023 21.4 1.9 6.5 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM69202.1 - 5.6e-10 39.0 46.6 0.043 13.8 0.3 7.1 5 1 1 6 6 6 5 C2H2-type zinc finger GAGA PF09237.11 KFM69202.1 - 3.7e-07 29.8 11.6 0.0001 22.0 0.1 4.9 1 1 5 6 6 6 2 GAGA factor zf_UBZ PF18439.1 KFM69202.1 - 0.0032 17.0 26.1 0.41 10.3 0.2 6.2 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM69202.1 - 0.0042 17.4 12.1 0.0042 17.4 12.1 5.1 1 1 2 4 4 4 1 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFM69202.1 - 0.0058 16.9 6.1 8.3 6.8 0.2 4.3 1 1 2 3 3 3 0 BolA-like protein zf-C2HC_2 PF13913.6 KFM69202.1 - 0.0082 16.0 28.2 1.7 8.7 0.0 6.6 6 1 0 6 6 6 1 zinc-finger of a C2HC-type FYVE PF01363.21 KFM69202.1 - 0.016 15.3 30.3 1.9 8.7 3.9 3.8 2 1 1 3 3 3 0 FYVE zinc finger zf-H2C2_5 PF13909.6 KFM69202.1 - 0.024 14.4 39.9 0.26 11.1 0.3 7.4 7 0 0 7 7 7 0 C2H2-type zinc-finger domain HNH_5 PF14279.6 KFM69202.1 - 0.025 14.5 26.6 2.7 7.9 0.3 5.9 5 1 0 5 5 5 0 HNH endonuclease ADK_lid PF05191.14 KFM69202.1 - 0.047 13.7 20.3 0.37 10.8 0.6 4.7 3 2 0 3 3 3 0 Adenylate kinase, active site lid YyzF PF14116.6 KFM69202.1 - 0.12 12.4 17.6 5.7 7.0 0.1 5.7 6 0 0 6 6 6 0 YyzF-like protein zf-C2H2_9 PF16293.5 KFM69202.1 - 0.14 12.1 21.0 3.4 7.6 0.2 5.8 1 1 5 6 6 6 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 KFM69202.1 - 0.17 12.0 26.5 2.5 8.3 0.8 6.1 1 1 5 6 6 6 0 KIAA1045 RING finger YceD PF02620.17 KFM69202.1 - 0.61 10.2 7.8 1.3 9.1 0.1 3.9 3 2 1 4 4 4 0 Large ribosomal RNA subunit accumulation protein YceD RecR PF02132.15 KFM69202.1 - 1.7 8.3 17.8 13 5.5 0.0 5.7 6 0 0 6 6 6 0 RecR protein DUF5330 PF17264.2 KFM69202.1 - 3.9 7.6 6.9 63 3.7 0.1 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5330) zinc_ribbon_15 PF17032.5 KFM69202.1 - 4 8.3 20.0 8.4 7.2 1.5 3.4 1 1 2 3 3 3 0 zinc-ribbon family zf-HIT PF04438.16 KFM69202.1 - 7.4 6.5 29.8 1.1 9.2 0.8 6.2 6 0 0 6 6 6 0 HIT zinc finger HRM PF02793.22 KFM69203.1 - 4.5e-13 49.3 11.6 4.5e-13 49.3 11.6 2.1 3 0 0 3 3 3 1 Hormone receptor domain 7tm_2 PF00002.24 KFM69204.1 - 3e-48 164.3 6.6 3e-48 164.3 6.6 1.4 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KFM69204.1 - 0.0044 16.2 7.0 0.0044 16.2 7.0 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Tmemb_185A PF10269.9 KFM69204.1 - 0.0056 16.4 2.6 0.091 12.4 1.2 2.3 1 1 1 2 2 2 1 Transmembrane Fragile-X-F protein DUF2339 PF10101.9 KFM69204.1 - 0.03 12.9 2.1 0.034 12.8 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Abhydrolase_9_N PF15420.6 KFM69204.1 - 0.066 13.2 2.2 0.095 12.7 2.2 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus CLP_protease PF00574.23 KFM69205.1 - 1.3e-45 155.5 0.0 1.6e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease Nop PF01798.18 KFM69206.1 - 5.5e-72 242.0 0.1 5.5e-72 242.0 0.1 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin FATC PF02260.20 KFM69206.1 - 0.39 10.6 0.9 0.65 9.9 0.0 1.9 2 0 0 2 2 2 0 FATC domain NOP5NT PF08156.13 KFM69207.1 - 6.1e-16 58.6 0.2 6.8e-16 58.4 0.2 1.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Transketolase_N PF00456.21 KFM69208.1 - 3.5e-38 131.4 0.0 6.1e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFM69208.1 - 2.4e-36 125.0 0.0 3.8e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFM69208.1 - 1.3e-27 96.2 0.0 2.5e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KFM69208.1 - 2.6e-07 30.2 0.0 0.00028 20.2 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KFM69208.1 - 1.3e-06 27.6 0.0 2.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFM69208.1 - 0.00013 21.8 0.1 0.0035 17.1 0.1 3.0 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFOR_II PF17147.4 KFM69208.1 - 0.017 15.4 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II XFP_N PF09364.10 KFM69208.1 - 0.027 13.3 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 XFP N-terminal domain EB PF01683.18 KFM69209.1 - 6e-06 26.4 18.8 0.0023 18.2 0.5 2.6 3 0 0 3 3 3 2 EB module EphA2_TM PF14575.6 KFM69209.1 - 0.0098 16.8 0.1 0.027 15.3 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM52 PF14979.6 KFM69209.1 - 0.038 13.9 4.6 0.31 11.0 0.0 3.0 2 1 1 3 3 3 0 Transmembrane 52 DUF202 PF02656.15 KFM69209.1 - 0.34 11.4 1.6 1.2 9.6 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF202) EGF_2 PF07974.13 KFM69209.1 - 3 8.3 23.1 0.93 9.9 5.1 4.0 4 0 0 4 4 4 0 EGF-like domain Ras PF00071.22 KFM69211.1 - 7.6e-23 80.9 0.0 8.7e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM69211.1 - 0.0022 18.2 0.0 0.0047 17.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase HTH_psq PF05225.16 KFM69213.1 - 5.9e-16 57.9 0.1 8.3e-16 57.5 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_psq PF05225.16 KFM69214.1 - 7.5e-15 54.4 0.0 1.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain AAA_33 PF13671.6 KFM69215.1 - 2e-27 96.1 0.0 3.2e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM69215.1 - 0.0084 16.7 0.0 0.015 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM69215.1 - 0.01 15.1 0.0 0.024 13.9 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KFM69215.1 - 0.083 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KFM69215.1 - 0.21 11.0 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 HTH_Tnp_Tc3_2 PF01498.18 KFM69216.1 - 2.7e-16 59.5 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69216.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69216.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69216.1 - 0.0024 17.6 0.6 0.0068 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69216.1 - 1.8 9.2 15.7 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_1 PF03184.19 KFM69218.1 - 2.9e-13 49.8 0.0 4.4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HD_5 PF13487.6 KFM69219.1 - 0.075 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 HD domain HR1 PF02185.16 KFM69220.1 - 6.9 6.9 8.8 0.4 10.8 1.0 3.0 4 0 0 4 4 4 0 Hr1 repeat Cadherin PF00028.17 KFM69222.1 - 1.5e-109 358.7 16.6 2.1e-20 73.0 0.0 7.1 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 KFM69222.1 - 9.6e-10 38.2 0.0 0.65 9.9 0.0 6.4 6 0 0 6 6 6 2 Cadherin-like RET_CLD1 PF17756.1 KFM69222.1 - 4.4e-08 33.4 0.0 0.24 11.7 0.0 4.9 5 0 0 5 5 5 2 RET Cadherin like domain 1 Cadherin_3 PF16184.5 KFM69222.1 - 4.9e-08 32.9 7.4 0.12 12.3 0.0 6.9 7 0 0 7 7 7 1 Cadherin-like Cadherin_pro PF08758.11 KFM69222.1 - 7.7e-05 22.8 0.9 1.8 8.8 0.0 5.2 6 0 0 6 6 6 1 Cadherin prodomain like TagA PF12561.8 KFM69222.1 - 0.01 16.3 0.0 0.19 12.2 0.1 2.5 2 1 0 2 2 2 1 ToxR activated gene A lipoprotein domain Cadherin_4 PF17803.1 KFM69222.1 - 0.029 15.0 5.4 29 5.4 0.5 4.8 4 1 0 4 4 4 0 Bacterial cadherin-like domain DUF2808 PF10989.8 KFM69222.1 - 0.044 13.8 0.5 0.43 10.5 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2808) Big_9 PF17963.1 KFM69222.1 - 0.05 14.3 16.7 0.14 12.9 1.0 5.0 4 1 1 5 5 5 0 Bacterial Ig domain He_PIG PF05345.12 KFM69222.1 - 5.2 7.3 9.5 1.3 9.3 0.1 4.1 3 0 0 3 3 3 0 Putative Ig domain Cadherin PF00028.17 KFM69223.1 - 2.7e-39 133.5 0.7 9.4e-18 64.5 0.0 3.7 4 0 0 4 4 4 3 Cadherin domain Cadherin_3 PF16184.5 KFM69223.1 - 0.00019 21.4 0.3 0.0075 16.3 0.1 2.5 2 0 0 2 2 2 1 Cadherin-like Cadherin_2 PF08266.12 KFM69223.1 - 0.00079 19.2 0.0 0.77 9.6 0.0 2.6 2 1 0 2 2 2 2 Cadherin-like Cadherin PF00028.17 KFM69224.1 - 8.1e-146 474.9 3.4 1.8e-22 79.5 0.2 8.2 8 0 0 8 8 8 8 Cadherin domain Cadherin_3 PF16184.5 KFM69224.1 - 1.5e-13 50.7 11.7 0.017 15.1 0.1 6.9 6 0 0 6 6 6 5 Cadherin-like Cadherin_2 PF08266.12 KFM69224.1 - 6.4e-10 38.7 0.0 0.068 13.0 0.0 6.4 7 0 0 7 7 7 3 Cadherin-like RET_CLD1 PF17756.1 KFM69224.1 - 9.1e-05 22.7 0.1 8.2 6.7 0.0 5.4 4 2 2 6 6 6 1 RET Cadherin like domain 1 EGF PF00008.27 KFM69224.1 - 0.00026 21.2 7.3 0.00026 21.2 7.3 3.2 3 0 0 3 3 3 1 EGF-like domain Cadherin_4 PF17803.1 KFM69224.1 - 0.00069 20.2 17.4 0.0024 18.5 2.0 5.8 5 0 0 5 5 5 1 Bacterial cadherin-like domain DUF2551 PF10826.8 KFM69224.1 - 0.016 15.4 0.0 2.3 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) hEGF PF12661.7 KFM69224.1 - 2.5 8.9 13.9 1.7 9.4 4.7 3.3 3 0 0 3 3 3 0 Human growth factor-like EGF Laminin_EGF PF00053.24 KFM69224.1 - 7.2 6.8 15.7 98 3.2 6.0 2.4 1 1 1 2 2 2 0 Laminin EGF domain He_PIG PF05345.12 KFM69224.1 - 8.5 6.6 7.6 6.7 7.0 0.1 4.2 5 0 0 5 5 5 0 Putative Ig domain EGF PF00008.27 KFM69225.1 - 4.2e-22 78.1 53.1 1.8e-08 34.5 6.7 4.6 4 0 0 4 4 4 4 EGF-like domain Laminin_G_2 PF02210.24 KFM69225.1 - 1.2e-21 77.6 0.0 1.7e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM69225.1 - 8.6e-15 55.1 0.0 1.4e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFM69225.1 - 4.1e-11 43.1 47.6 0.00024 21.6 6.2 5.2 4 0 0 4 4 4 4 Human growth factor-like EGF EGF_CA PF07645.15 KFM69225.1 - 4.2e-07 30.1 21.1 9.3e-07 29.0 4.5 4.5 4 0 0 4 4 4 2 Calcium-binding EGF domain Orthoreo_P10 PF07204.11 KFM69225.1 - 0.00036 20.4 1.2 0.00079 19.3 1.2 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 RCR PF12273.8 KFM69225.1 - 0.0031 18.1 0.0 0.0055 17.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red MLANA PF14991.6 KFM69225.1 - 0.0034 17.7 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 Protein melan-A EGF_3 PF12947.7 KFM69225.1 - 0.0095 16.1 51.1 0.014 15.6 7.5 4.6 3 1 1 4 4 4 3 EGF domain TMEM100 PF16311.5 KFM69225.1 - 0.021 14.4 0.3 0.043 13.4 0.3 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 DAG1 PF05454.11 KFM69225.1 - 0.027 13.9 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Laminin_G_3 PF13385.6 KFM69225.1 - 0.034 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Adeno_E3_CR2 PF02439.15 KFM69225.1 - 0.044 13.5 2.0 0.075 12.8 2.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PgaD PF13994.6 KFM69225.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein MIG-14_Wnt-bd PF06664.12 KFM69225.1 - 0.14 11.4 0.1 0.19 10.9 0.1 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion EphA2_TM PF14575.6 KFM69225.1 - 0.15 13.0 0.0 0.25 12.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EGF_2 PF07974.13 KFM69225.1 - 2.8 8.4 60.6 0.64 10.4 8.7 4.5 4 0 0 4 4 4 0 EGF-like domain zf-H2C2_2 PF13465.6 KFM69226.1 - 3.3e-82 267.5 83.5 2.5e-08 34.0 0.8 13.0 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69226.1 - 7.4e-62 202.5 121.5 1.5e-06 28.3 1.1 12.9 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-met PF12874.7 KFM69226.1 - 9.5e-38 127.5 107.8 0.00018 21.8 2.4 12.4 12 0 0 12 12 12 11 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM69226.1 - 1.2e-37 125.3 112.0 0.0021 18.7 3.4 12.8 13 0 0 13 13 13 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM69226.1 - 5.4e-19 68.0 80.6 0.073 13.4 1.3 12.6 12 0 0 12 12 12 10 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM69226.1 - 2.7e-13 49.4 76.2 0.0034 17.1 0.2 13.1 13 0 0 13 13 13 9 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM69226.1 - 1.6e-09 37.5 28.2 0.43 10.6 0.3 7.5 2 2 3 7 7 7 7 Adenylate kinase, active site lid zf-C2H2_6 PF13912.6 KFM69226.1 - 9.7e-09 35.0 98.4 0.15 12.1 1.8 14.0 14 1 0 14 14 14 7 C2H2-type zinc finger Mga PF05043.13 KFM69226.1 - 0.00011 22.7 12.1 1 10.0 0.1 5.4 6 0 0 6 6 5 1 Mga helix-turn-helix domain zf-C2HC_2 PF13913.6 KFM69226.1 - 0.00054 19.8 50.1 6.2 6.9 0.1 11.9 12 0 0 12 12 12 1 zinc-finger of a C2HC-type Tox-HNH-HHH PF15637.6 KFM69226.1 - 0.00072 19.7 11.7 5.4 7.2 0.1 5.4 1 1 5 7 7 7 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-RRPl_C4 PF17026.5 KFM69226.1 - 0.0017 18.4 52.9 0.042 14.0 8.6 5.3 1 1 4 5 5 5 3 Putative ribonucleoprotein zinc-finger pf C4 type DUF952 PF06108.12 KFM69226.1 - 0.0021 18.0 2.5 3.2 7.8 0.0 4.7 1 1 4 5 5 5 1 Protein of unknown function (DUF952) FAM110_N PF14161.6 KFM69226.1 - 0.0031 17.7 0.1 17 5.7 0.0 4.2 1 1 4 5 5 5 0 Centrosome-associated N terminus DUF3396 PF11876.8 KFM69226.1 - 0.0088 15.5 0.0 36 3.7 0.0 4.5 1 1 3 5 5 5 0 Protein of unknown function (DUF3396) C1_1 PF00130.22 KFM69226.1 - 0.009 15.9 65.7 0.46 10.4 5.9 9.9 3 3 6 9 9 9 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHCC PF10276.9 KFM69226.1 - 0.019 15.0 14.2 41 4.3 0.0 8.0 11 0 0 11 11 9 0 Zinc-finger domain DUF2256 PF10013.9 KFM69226.1 - 0.022 14.8 44.1 12 6.1 0.1 10.6 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) Nore1-SARAH PF16517.5 KFM69226.1 - 0.035 14.0 0.0 13 5.7 0.0 4.6 5 0 0 5 5 4 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain BolA PF01722.18 KFM69226.1 - 0.049 13.9 27.9 2.6 8.4 0.8 7.2 1 1 7 8 8 8 0 BolA-like protein zf-DBF PF07535.12 KFM69226.1 - 0.11 12.7 59.2 9.5 6.4 1.0 11.1 11 1 1 12 12 11 0 DBF zinc finger NAD_kinase PF01513.21 KFM69226.1 - 0.28 10.4 5.7 21 4.2 0.1 4.5 1 1 1 2 2 2 0 ATP-NAD kinase YyzF PF14116.6 KFM69226.1 - 1.2 9.3 34.9 22 5.2 0.1 10.2 11 0 0 11 11 11 0 YyzF-like protein zf-Sec23_Sec24 PF04810.15 KFM69226.1 - 1.3 9.2 46.8 5.8 7.0 0.1 10.6 11 1 1 12 12 12 0 Sec23/Sec24 zinc finger Baculo_IE-1 PF05290.11 KFM69226.1 - 2.3 8.2 40.9 4.2 7.3 3.2 6.8 1 1 4 5 5 5 0 Baculovirus immediate-early protein (IE-0) Flag1_repress PF03614.13 KFM69226.1 - 3.9 7.2 8.9 2.8 7.7 0.6 3.5 1 1 3 4 4 4 0 Repressor of phase-1 flagellin FYVE PF01363.21 KFM69226.1 - 9.5 6.4 69.7 1.1 9.5 10.5 7.0 1 1 7 8 8 8 0 FYVE zinc finger zf-H2C2_2 PF13465.6 KFM69227.1 - 1.7e-46 154.7 39.4 1.3e-08 34.9 1.1 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69227.1 - 5.6e-30 102.1 53.1 1.9e-06 28.0 0.2 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69227.1 - 1.9e-23 81.1 50.7 0.0003 21.4 0.2 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFM69227.1 - 3.9e-15 55.7 47.3 0.00023 21.4 0.4 6.5 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM69227.1 - 4.6e-09 36.3 33.0 0.12 12.7 0.3 6.6 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM69227.1 - 1.1e-08 34.8 39.6 0.13 12.3 1.5 6.8 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM69227.1 - 1.1e-07 31.4 33.4 0.017 14.9 1.0 6.4 6 0 0 6 6 6 4 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM69227.1 - 0.00047 20.1 21.3 0.027 14.5 3.4 4.4 4 0 0 4 4 4 2 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KFM69227.1 - 0.00048 20.1 29.0 0.93 9.6 0.5 6.1 5 1 1 6 6 6 2 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM69227.1 - 0.0017 18.2 25.6 1.3 9.1 0.6 6.5 6 0 0 6 6 6 1 zinc-finger of a C2HC-type BolA PF01722.18 KFM69227.1 - 0.0032 17.7 3.1 10 6.5 0.0 3.8 1 1 1 2 2 2 0 BolA-like protein zf_UBZ PF18439.1 KFM69227.1 - 0.012 15.2 25.9 0.91 9.2 0.4 6.2 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM69227.1 - 0.015 15.4 19.8 1.1 9.5 1.5 4.6 4 1 0 4 4 4 0 Zinc ribbon domain TRAF6_Z2 PF18048.1 KFM69227.1 - 0.03 14.4 33.7 3.7 7.7 0.2 6.2 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 Tox-HNH-HHH PF15637.6 KFM69227.1 - 0.035 14.3 0.1 1.8 8.8 0.1 2.9 1 1 4 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Zf_RING PF16744.5 KFM69227.1 - 0.071 13.2 31.1 0.74 10.0 1.0 5.8 1 1 3 5 5 5 0 KIAA1045 RING finger zf-MYST PF17772.1 KFM69227.1 - 0.074 12.7 0.1 0.074 12.7 0.1 5.6 3 3 3 6 6 6 0 MYST family zinc finger domain zf-CCHC_2 PF13696.6 KFM69227.1 - 0.11 12.4 1.2 0.11 12.4 1.2 6.3 6 0 0 6 6 6 0 Zinc knuckle C1_4 PF07975.12 KFM69227.1 - 0.28 11.5 31.9 0.75 10.1 8.4 3.9 1 1 3 4 4 4 0 TFIIH C1-like domain FYVE PF01363.21 KFM69227.1 - 0.38 10.9 36.9 0.11 12.6 11.1 3.5 1 1 0 2 2 2 0 FYVE zinc finger zf-RRPl_C4 PF17026.5 KFM69227.1 - 0.49 10.5 27.2 0.32 11.1 7.8 3.0 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type YyzF PF14116.6 KFM69227.1 - 0.64 10.1 13.7 15 5.7 0.1 5.4 6 0 0 6 6 6 0 YyzF-like protein zf-C2H2_9 PF16293.5 KFM69227.1 - 0.84 9.5 28.6 5.1 7.0 0.6 5.8 3 2 3 6 6 6 0 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFM69227.1 - 1.1 9.4 24.2 12 6.1 0.0 6.2 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_3rep PF18868.1 KFM69227.1 - 2.5 8.8 26.7 0.35 11.6 1.5 4.5 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-trcl PF13451.6 KFM69227.1 - 7 6.6 22.3 26 4.8 0.1 6.2 6 0 0 6 6 6 0 Probable zinc-ribbon domain zf-C2H2_2 PF12756.7 KFM69227.1 - 7.2 7.0 44.2 5.1 7.5 2.7 5.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM69228.1 - 7.2e-72 234.9 67.2 2.9e-09 36.9 0.2 11.8 11 1 0 11 11 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69228.1 - 8.9e-49 161.3 83.7 2.6e-05 24.4 2.0 11.2 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69228.1 - 2.3e-33 111.9 77.3 0.0012 19.5 1.2 10.8 11 0 0 11 11 11 10 C2H2-type zinc finger zf-met PF12874.7 KFM69228.1 - 5e-20 71.2 71.1 0.00032 21.0 3.3 10.6 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM69228.1 - 2.6e-19 68.8 72.7 0.00046 20.1 1.6 11.5 12 0 0 12 12 11 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM69228.1 - 1.5e-11 44.2 54.6 0.076 13.3 0.7 10.9 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM69228.1 - 4.8e-08 32.7 17.5 1.2 9.0 0.1 8.3 1 1 8 9 9 9 3 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM69228.1 - 9.7e-06 25.5 32.2 4.8 7.3 0.0 9.8 7 2 3 10 10 10 1 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM69228.1 - 0.00018 21.3 38.0 0.91 9.4 0.6 10.3 4 2 7 11 11 11 2 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM69228.1 - 0.0012 19.0 34.6 0.017 15.2 5.9 5.0 1 1 5 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type zf-H2C2_5 PF13909.6 KFM69228.1 - 0.0025 17.5 74.3 0.14 11.9 0.7 11.0 12 0 0 12 12 12 5 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM69228.1 - 0.023 14.4 0.6 0.023 14.4 0.6 9.7 10 1 0 10 10 10 0 zinc-finger C2H2-type zf-FPG_IleRS PF06827.14 KFM69228.1 - 0.029 14.2 26.2 8.3 6.4 0.1 8.5 9 0 0 9 9 9 0 Zinc finger found in FPG and IleRS Complex1_49kDa PF00346.19 KFM69228.1 - 0.037 13.1 0.2 2 7.4 0.0 3.1 1 1 3 4 4 4 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Tox-HNH-HHH PF15637.6 KFM69228.1 - 0.038 14.1 1.4 5.8 7.1 0.1 3.2 2 2 1 3 3 3 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif C1_4 PF07975.12 KFM69228.1 - 0.051 13.8 38.3 3.3 8.0 1.2 6.9 2 1 5 8 8 8 0 TFIIH C1-like domain zf_UBZ PF18439.1 KFM69228.1 - 0.15 11.7 32.9 8.4 6.1 0.1 9.2 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger CxC5 PF18718.1 KFM69228.1 - 0.3 11.2 19.8 0.33 11.0 0.7 4.8 3 1 1 5 5 5 0 CxC5 like cysteine cluster associated with KDZ transposases zf-MYST PF17772.1 KFM69228.1 - 0.38 10.4 43.2 0.25 11.0 0.2 9.3 5 3 5 10 10 10 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 KFM69228.1 - 0.44 10.9 62.4 8.8 6.7 3.0 9.5 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM69228.1 - 0.45 11.3 32.8 2.2 9.1 1.2 5.7 1 1 3 6 6 6 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM69228.1 - 0.65 10.2 30.1 3.2 7.9 2.6 6.8 3 3 5 8 8 8 0 Zinc ribbon domain Zf_RING PF16744.5 KFM69228.1 - 0.76 9.9 42.3 9.6 6.4 2.6 9.4 2 2 6 8 8 8 0 KIAA1045 RING finger zf-C2HC_2 PF13913.6 KFM69228.1 - 1.5 8.8 34.9 16 5.6 0.1 9.6 10 0 0 10 10 10 0 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM69228.1 - 2.1 8.4 29.7 0.83 9.7 0.9 6.7 4 2 2 6 6 6 0 Adenylate kinase, active site lid zf-H2C2_2 PF13465.6 KFM69229.1 - 1.3e-66 218.2 52.7 4.9e-08 33.0 0.5 10.1 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69229.1 - 1.7e-48 160.4 69.4 6.4e-07 29.5 1.6 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69229.1 - 4.2e-33 111.1 65.5 0.00016 22.2 0.2 9.2 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM69229.1 - 8.3e-20 70.3 52.5 0.0011 18.9 0.5 9.4 9 0 0 9 9 9 7 C2H2-type zinc finger zf-met PF12874.7 KFM69229.1 - 1.8e-19 69.4 63.0 0.0011 19.3 1.2 9.3 9 0 0 9 9 9 7 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM69229.1 - 4.5e-18 64.7 47.1 0.00037 20.2 0.4 9.4 9 0 0 9 9 9 7 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM69229.1 - 1.9e-12 47.1 50.8 0.0022 18.2 0.7 9.6 9 1 1 10 10 10 6 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM69229.1 - 1.5e-07 31.1 21.8 0.091 12.6 0.1 6.8 2 2 6 8 8 8 4 GAGA factor BolA PF01722.18 KFM69229.1 - 1.1e-06 28.8 10.6 0.29 11.5 0.3 5.4 1 1 3 5 5 5 2 BolA-like protein zf_UBZ PF18439.1 KFM69229.1 - 2.1e-06 27.2 33.9 1.2 8.8 0.1 8.0 8 0 0 8 8 8 4 Ubiquitin-Binding Zinc Finger HNH_5 PF14279.6 KFM69229.1 - 6.1e-06 26.0 38.0 2.6 8.0 0.1 8.4 6 2 1 7 7 7 3 HNH endonuclease zf-C2H2_9 PF16293.5 KFM69229.1 - 1e-05 25.3 34.1 1.8 8.5 0.2 8.2 4 4 4 8 8 8 3 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM69229.1 - 3e-05 23.8 30.0 1.3 9.0 0.0 8.4 8 0 0 8 8 8 2 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM69229.1 - 0.00016 21.2 38.3 0.61 9.7 0.1 8.3 3 2 6 9 9 9 4 MYST family zinc finger domain zf-RRPl_C4 PF17026.5 KFM69229.1 - 0.0002 21.4 35.2 0.022 14.9 6.4 4.0 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFM69229.1 - 0.00034 21.3 32.5 0.45 11.3 1.9 5.0 2 1 3 5 5 5 3 zinc-ribbon family Tox-HNH-HHH PF15637.6 KFM69229.1 - 0.00053 20.1 0.7 6.3 7.0 0.0 4.1 1 1 5 6 6 6 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Herpes_ORF11 PF04797.13 KFM69229.1 - 0.00058 18.8 1.4 0.23 10.2 0.1 2.2 1 1 0 2 2 2 2 Herpesvirus dUTPase protein zf-C2H2_2 PF12756.7 KFM69229.1 - 0.00069 19.9 57.4 1.5 9.2 1.2 8.6 1 1 7 8 8 8 2 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.15 KFM69229.1 - 0.00075 19.5 34.6 0.49 10.5 0.4 8.3 8 1 1 9 9 9 3 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM69229.1 - 0.0018 18.2 28.2 1 9.4 0.7 6.1 2 1 6 8 8 8 3 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 KFM69229.1 - 0.0038 17.1 33.6 2 8.4 0.2 8.8 9 0 0 9 9 9 1 Prokaryotic RING finger family 1 DUF2256 PF10013.9 KFM69229.1 - 0.0082 16.2 33.6 13 6.0 0.6 8.9 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) Zf_RING PF16744.5 KFM69229.1 - 0.03 14.4 39.1 9 6.5 0.5 8.6 1 1 7 8 8 8 0 KIAA1045 RING finger FBA_3 PF08268.12 KFM69229.1 - 0.064 13.2 0.7 12 5.8 0.0 3.2 1 1 1 3 3 3 0 F-box associated domain Zn-ribbon_8 PF09723.10 KFM69229.1 - 0.083 13.0 30.0 1.6 8.9 0.7 6.2 3 2 4 7 7 7 0 Zinc ribbon domain C1_1 PF00130.22 KFM69229.1 - 0.14 12.1 46.3 9 6.3 0.5 8.0 1 1 5 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYDLN_acid PF09538.10 KFM69229.1 - 0.37 11.5 18.5 7.2 7.4 0.4 6.1 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) FYVE PF01363.21 KFM69229.1 - 0.49 10.6 45.8 0.097 12.8 7.3 5.5 3 2 2 5 5 5 0 FYVE zinc finger C5HCH PF17982.1 KFM69229.1 - 4.5 7.5 36.5 0.85 9.8 1.7 7.7 5 2 3 8 8 8 0 NSD Cys-His rich domain TRAF6_Z2 PF18048.1 KFM69229.1 - 4.7 7.4 47.2 1.7 8.8 1.1 8.8 9 1 0 9 9 9 0 TNF receptor-associated factor 6 zinc finger 2 zf-HIT PF04438.16 KFM69229.1 - 8.4 6.4 44.5 18 5.3 0.5 9.0 9 0 0 9 9 9 0 HIT zinc finger zf-H2C2_2 PF13465.6 KFM69230.1 - 3e-73 239.2 81.8 9.1e-09 35.4 2.6 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69230.1 - 2.3e-51 169.5 87.7 5.7e-06 26.5 2.1 11.2 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69230.1 - 3.8e-36 120.6 82.7 0.0012 19.5 1.7 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM69230.1 - 4.2e-15 55.5 72.1 0.00017 21.9 1.4 11.3 11 0 0 11 11 11 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM69230.1 - 5.2e-15 55.0 77.5 0.0034 17.3 0.4 12.5 11 2 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM69230.1 - 1.4e-07 31.1 66.3 0.019 14.7 0.3 11.6 11 1 0 11 11 11 4 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM69230.1 - 4e-07 30.0 36.1 0.038 14.0 0.4 10.4 10 1 1 11 11 11 2 Sec23/Sec24 zinc finger BolA PF01722.18 KFM69230.1 - 4.1e-05 23.8 11.3 0.28 11.5 0.3 6.1 1 1 3 5 5 5 1 BolA-like protein zf-RRPl_C4 PF17026.5 KFM69230.1 - 0.00012 22.1 40.3 1.3 9.1 4.4 5.1 1 1 4 5 5 5 4 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_9 PF16293.5 KFM69230.1 - 0.00025 20.8 38.5 3.1 7.7 0.3 10.0 3 3 8 11 11 11 2 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM69230.1 - 0.00073 19.3 23.3 1.5 8.6 0.0 8.0 2 2 8 10 10 10 1 GAGA factor zf-C2H2_jaz PF12171.8 KFM69230.1 - 0.0016 18.6 57.4 0.34 11.3 0.4 11.2 11 1 0 11 11 10 4 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 KFM69230.1 - 0.0023 17.5 49.6 0.48 10.1 0.9 10.4 4 2 7 11 11 11 4 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFM69230.1 - 0.0046 17.7 37.9 3.1 8.6 1.5 5.8 2 2 4 6 6 6 3 zinc-ribbon family DUF3338 PF11819.8 KFM69230.1 - 0.012 15.5 2.5 16 5.5 0.2 4.4 3 3 2 5 5 5 0 Domain of unknown function (DUF3338) DUF2256 PF10013.9 KFM69230.1 - 0.013 15.6 37.6 5.4 7.2 0.1 10.5 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KFM69230.1 - 0.055 13.8 69.7 2.2 8.7 2.4 10.0 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) Complex1_49kDa PF00346.19 KFM69230.1 - 0.064 12.3 0.2 7.5 5.5 0.0 2.5 1 1 1 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf_UBZ PF18439.1 KFM69230.1 - 0.12 12.0 46.4 4.6 6.9 0.1 10.8 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM69230.1 - 0.2 11.8 38.0 2.8 8.1 0.7 7.2 4 4 4 8 8 8 0 Zinc ribbon domain BHD_1 PF10403.9 KFM69230.1 - 0.35 10.7 6.1 27 4.7 0.0 4.4 3 2 0 3 3 3 0 Rad4 beta-hairpin domain 1 ADK_lid PF05191.14 KFM69230.1 - 0.43 10.6 34.3 0.22 11.5 1.2 7.0 3 1 4 7 7 7 0 Adenylate kinase, active site lid Zf_RING PF16744.5 KFM69230.1 - 1.7 8.8 46.6 1.8 8.7 2.0 9.9 1 1 10 11 11 10 0 KIAA1045 RING finger TRAF6_Z2 PF18048.1 KFM69230.1 - 1.9 8.7 50.2 0.63 10.2 0.5 9.9 10 0 0 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 Z1 PF10593.9 KFM69230.1 - 5.1 6.5 6.7 27 4.1 0.4 3.3 4 0 0 4 4 4 0 Z1 domain FYVE PF01363.21 KFM69230.1 - 5.6 7.2 51.3 5 7.3 0.1 7.5 2 1 3 5 5 4 0 FYVE zinc finger ARL6IP6 PF15062.6 KFM69232.1 - 0.072 13.2 0.0 0.088 13.0 0.0 1.1 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Lipoprotein_2 PF00921.17 KFM69233.1 - 0.013 15.0 0.3 0.015 14.9 0.3 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein SNF PF00209.18 KFM69234.1 - 6.4e-37 127.4 2.3 7e-37 127.3 2.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3865 PF12981.7 KFM69235.1 - 0.053 13.4 0.0 0.056 13.3 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) DUF2090 PF09863.9 KFM69237.1 - 0.015 14.4 0.0 0.018 14.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Flp_C PF05202.12 KFM69237.1 - 0.036 13.6 0.2 0.036 13.6 0.2 1.1 1 0 0 1 1 1 0 Recombinase Flp protein Zincin_1 PF06262.11 KFM69237.1 - 0.061 13.4 0.0 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase Basic PF01586.16 KFM69238.1 - 2.6e-10 41.3 1.1 2.6e-10 41.3 1.1 4.0 3 1 2 5 5 5 1 Myogenic Basic domain HLH PF00010.26 KFM69238.1 - 0.013 15.4 7.0 0.035 14.1 7.0 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain adh_short PF00106.25 KFM69240.1 - 9.2e-46 155.8 0.1 1.2e-45 155.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM69240.1 - 1.8e-29 103.0 0.0 2.6e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM69240.1 - 9.4e-11 41.9 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 KFM69240.1 - 0.03 14.4 0.2 0.89 9.6 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Kunitz_BPTI PF00014.23 KFM69242.1 - 4.6e-130 423.8 135.0 1.8e-19 69.7 7.4 11.3 10 0 0 10 10 10 8 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.16 KFM69242.1 - 1.3e-37 127.7 0.0 3.7e-15 55.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM69242.1 - 7.8e-33 112.9 0.1 1.2e-11 45.0 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFM69242.1 - 9.4e-26 89.8 0.0 2.3e-11 43.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM69242.1 - 1e-23 83.4 0.0 1.1e-07 32.1 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM69242.1 - 6.1e-15 55.3 5.8 1.7e-05 25.0 0.0 6.6 6 2 1 7 7 7 3 Immunoglobulin V-set domain PLAC PF08686.11 KFM69242.1 - 2.6e-07 31.3 7.6 2.6e-07 31.3 7.6 5.5 5 0 0 5 5 5 1 PLAC (protease and lacunin) domain Ig_6 PF18452.1 KFM69242.1 - 1.6e-06 27.6 0.0 0.22 11.1 0.0 4.1 3 0 0 3 3 3 3 Immunoglobulin domain Receptor_2B4 PF11465.8 KFM69242.1 - 2.5e-06 27.6 0.0 0.0053 16.9 0.0 3.3 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFM69242.1 - 0.0037 17.3 0.0 0.44 10.6 0.0 2.6 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain DUF2380 PF09533.10 KFM69243.1 - 2.7 7.6 5.2 3.2 7.3 5.2 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) DUF1743 PF08489.11 KFM69244.1 - 0.047 13.7 0.0 0.047 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) zf-H2C2_2 PF13465.6 KFM69245.1 - 1.6e-69 227.4 95.9 1.9e-08 34.3 0.5 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69245.1 - 4.3e-54 178.0 112.9 1.3e-06 28.5 1.9 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69245.1 - 1.2e-41 137.7 101.4 0.00024 21.7 1.1 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM69245.1 - 4.2e-27 93.6 91.2 2.8e-05 24.0 0.1 12.5 12 1 0 12 12 12 10 C2H2-type zinc finger zf-met PF12874.7 KFM69245.1 - 3.1e-24 84.6 96.5 0.00036 20.8 0.7 12.8 12 1 0 12 12 12 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM69245.1 - 7.1e-16 58.0 89.5 0.012 15.9 0.3 12.7 10 3 2 12 12 12 9 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM69245.1 - 4.1e-07 30.2 10.1 1.5 9.1 0.0 6.1 2 2 2 4 4 4 3 BolA-like protein Zn-ribbon_8 PF09723.10 KFM69245.1 - 0.0012 18.9 35.3 2 8.6 1.1 8.1 6 1 3 9 9 9 3 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFM69245.1 - 0.012 15.5 47.0 0.25 11.3 0.1 11.0 12 0 0 12 12 12 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM69245.1 - 0.047 13.3 45.9 5.6 6.6 0.1 11.1 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 KFM69245.1 - 0.45 11.0 62.8 0.44 11.0 2.0 9.6 3 2 7 10 10 10 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.21 KFM69245.1 - 1.3 9.3 57.9 3.9 7.7 8.3 6.6 2 1 5 7 7 7 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM69245.1 - 1.5 9.6 45.3 2.5 8.9 0.3 6.3 3 2 5 8 8 8 0 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM69245.1 - 1.7 9.0 69.4 0.9 9.9 0.1 10.2 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) Ta0938 PF11494.8 KFM69245.1 - 2.4 8.5 28.2 0.97 9.7 0.3 7.4 1 1 5 7 7 7 0 Ta0938 zf-H2C2_2 PF13465.6 KFM69246.1 - 5.9e-68 222.5 67.4 5.5e-08 32.9 0.3 11.1 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69246.1 - 1.4e-50 167.0 83.5 1.1e-05 25.6 1.7 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69246.1 - 7.4e-37 122.8 77.0 0.0011 19.7 1.1 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM69246.1 - 4.1e-20 71.3 58.9 0.0071 16.3 0.3 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM69246.1 - 2.2e-15 56.5 65.7 0.016 15.6 0.2 10.5 10 0 0 10 10 10 7 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM69246.1 - 1.3e-13 50.4 58.1 0.072 12.9 0.2 10.5 10 0 0 10 10 10 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM69246.1 - 2.1e-08 34.2 48.3 0.14 12.5 0.1 10.5 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM69246.1 - 6.8e-07 29.0 30.2 0.1 12.5 0.1 9.0 9 0 0 9 9 9 2 zinc-finger of a C2HC-type BolA PF01722.18 KFM69246.1 - 1e-05 25.7 11.2 0.25 11.7 0.4 6.0 1 1 6 7 7 7 1 BolA-like protein GAGA PF09237.11 KFM69246.1 - 1.4e-05 24.8 28.6 0.5 10.2 0.2 8.6 2 2 8 10 10 10 3 GAGA factor zf-C2H2_9 PF16293.5 KFM69246.1 - 0.00035 20.3 39.1 2.4 8.0 0.2 9.3 4 3 6 10 10 10 1 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFM69246.1 - 0.00067 19.7 34.7 2.8 8.2 0.6 9.7 10 0 0 10 10 10 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KFM69246.1 - 0.0009 19.5 60.4 3.8 7.9 0.2 9.4 1 1 8 9 9 9 2 C2H2 type zinc-finger (2 copies) Ndufs5 PF10200.9 KFM69246.1 - 0.0014 18.8 9.4 16 5.8 0.1 6.0 1 1 6 7 7 7 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa zf-MYST PF17772.1 KFM69246.1 - 0.0071 15.9 40.7 0.74 9.5 0.3 8.9 7 2 3 10 10 10 2 MYST family zinc finger domain Prok-RING_1 PF14446.6 KFM69246.1 - 0.014 15.3 34.8 25 4.9 0.2 9.8 10 0 0 10 10 10 0 Prokaryotic RING finger family 1 PH_3 PF14593.6 KFM69246.1 - 0.015 15.4 0.5 6.6 6.9 0.0 4.1 1 1 2 4 4 4 0 PH domain DUF2039 PF10217.9 KFM69246.1 - 0.047 14.0 31.0 0.77 10.1 0.8 5.2 1 1 4 5 5 5 0 Uncharacterized conserved protein (DUF2039) K_oxygenase PF13434.6 KFM69246.1 - 0.056 12.6 0.4 0.73 8.9 0.1 2.7 1 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) ADK_lid PF05191.14 KFM69246.1 - 0.065 13.2 38.6 0.65 10.0 2.3 6.8 6 1 1 7 7 7 0 Adenylate kinase, active site lid C1_1 PF00130.22 KFM69246.1 - 0.17 11.8 46.3 2 8.4 5.3 8.0 2 1 7 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFM69246.1 - 0.19 12.5 32.6 0.52 11.1 1.3 5.2 1 1 4 5 5 5 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 KFM69246.1 - 0.25 11.4 33.4 1.1 9.4 0.4 8.3 8 2 1 9 9 9 0 Sec23/Sec24 zinc finger DNA_primase_S PF01896.19 KFM69246.1 - 0.95 9.5 9.5 2.5 8.1 3.5 3.7 1 1 0 2 2 2 0 DNA primase small subunit zf-DBF PF07535.12 KFM69246.1 - 1.1 9.4 31.4 9.7 6.4 0.1 7.3 9 0 0 9 9 8 0 DBF zinc finger Zn-ribbon_8 PF09723.10 KFM69246.1 - 3 8.0 31.1 1.1 9.5 1.2 6.3 3 3 5 8 8 8 0 Zinc ribbon domain Tnp_P_element PF12017.8 KFM69247.1 - 0.013 14.9 1.7 0.059 12.8 0.1 2.1 2 0 0 2 2 2 0 Transposase protein BLM10_mid PF16507.5 KFM69249.1 - 5e-07 28.7 0.1 8.5e-07 28.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region BLM10_mid PF16507.5 KFM69250.1 - 1.6e-64 218.5 0.7 1e-62 212.5 0.7 2.1 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region FH2 PF02181.23 KFM69251.1 - 0.0027 16.9 0.3 0.0028 16.9 0.3 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain PatG_C PF18065.1 KFM69251.1 - 0.15 12.0 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 PatG C-terminal Ig_3 PF13927.6 KFM69253.1 - 3.4e-83 274.3 6.4 1e-15 58.0 0.1 7.1 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KFM69253.1 - 9.9e-83 272.3 0.2 5.1e-17 61.7 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain ig PF00047.25 KFM69253.1 - 2.4e-53 178.3 1.1 6.5e-11 42.3 0.1 6.4 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 KFM69253.1 - 9.9e-49 163.6 1.9 9.2e-09 35.5 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 KFM69253.1 - 4.3e-40 135.9 5.9 8.5e-14 51.7 0.2 4.7 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 KFM69253.1 - 2.9e-25 88.6 12.1 4e-05 23.8 0.1 10.8 7 5 2 9 9 9 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM69253.1 - 1.4e-13 50.7 2.2 0.094 12.8 0.0 6.2 6 0 0 6 6 6 4 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM69253.1 - 6.6e-10 39.1 0.9 1.7 9.0 0.0 5.2 5 0 0 5 5 5 4 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFM69253.1 - 1.5e-09 37.3 0.0 0.91 9.1 0.0 5.2 6 0 0 6 6 6 4 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM69253.1 - 3.9e-06 26.8 3.3 1.9 8.6 0.0 7.2 6 1 1 8 8 8 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFM69253.1 - 9.4e-05 22.4 1.1 5.6 7.1 0.0 5.0 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain C2-set PF05790.15 KFM69253.1 - 0.00021 21.4 0.7 22 5.3 0.0 5.1 6 0 0 6 6 5 0 Immunoglobulin C2-set domain Pur_ac_phosph_N PF16656.5 KFM69253.1 - 0.044 14.4 0.0 0.35 11.5 0.0 2.6 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain V-set_CD47 PF08204.11 KFM69253.1 - 0.074 13.0 3.3 13 5.7 0.1 4.2 4 1 0 4 4 4 0 CD47 immunoglobulin-like domain RNase_PH_C PF03725.15 KFM69254.1 - 1.1e-06 28.6 0.6 1.8e-06 27.9 0.4 1.5 1 1 1 2 2 2 1 3' exoribonuclease family, domain 2 zf-CCCH_6 PF18585.1 KFM69255.1 - 0.047 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF4817 PF16087.5 KFM69256.1 - 2.2e-07 30.6 0.1 2.9e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) DDE_Tnp_1_7 PF13843.6 KFM69258.1 - 0.0036 16.7 0.0 0.0044 16.4 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 DUF4371 PF14291.6 KFM69259.1 - 3.1e-08 33.6 0.8 3.1e-08 33.6 0.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Zip PF02535.22 KFM69259.1 - 0.28 10.4 3.0 0.31 10.2 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 KFM69259.1 - 0.51 9.1 10.1 0.85 8.3 10.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPL5 PF18168.1 KFM69259.1 - 2.7 7.2 9.5 5.3 6.2 9.5 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 KFM69259.1 - 6.5 5.4 13.9 9.8 4.8 13.9 1.2 1 0 0 1 1 1 0 Presenilin I-set PF07679.16 KFM69260.1 - 2.6e-12 46.6 0.0 3.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM69260.1 - 1.5e-11 44.7 0.1 2.3e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain IGFBP PF00219.18 KFM69260.1 - 4.9e-09 36.7 19.2 4.9e-09 36.7 19.2 2.1 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Kazal_1 PF00050.21 KFM69260.1 - 2.5e-08 33.8 1.4 8e-08 32.2 1.4 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Ig_2 PF13895.6 KFM69260.1 - 1.3e-07 31.8 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.15 KFM69260.1 - 1.1e-06 28.6 2.4 1.1e-06 28.6 2.4 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain ig PF00047.25 KFM69260.1 - 4.9e-06 26.6 0.0 8.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM69260.1 - 0.0012 18.9 0.0 0.0033 17.6 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Lectin_N PF03954.14 KFM69261.1 - 0.077 12.7 0.2 0.099 12.4 0.2 1.1 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DDE_Tnp_4 PF13359.6 KFM69262.1 - 4.4e-15 55.7 0.0 9.5e-15 54.6 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF2102 PF09875.9 KFM69262.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Lamp PF01299.17 KFM69263.1 - 9.6e-17 61.2 1.4 1.5e-16 60.6 1.4 1.3 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Rax2 PF12768.7 KFM69263.1 - 0.00039 19.9 0.1 0.0009 18.8 0.1 1.7 2 0 0 2 2 2 1 Cortical protein marker for cell polarity CTV_P6 PF06706.11 KFM69263.1 - 0.021 14.5 0.4 0.052 13.2 0.4 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein PRCC PF10253.9 KFM69263.1 - 0.05 14.4 2.8 0.057 14.2 2.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Endomucin PF07010.12 KFM69263.1 - 0.22 11.5 22.0 0.95 9.4 20.2 2.1 2 0 0 2 2 2 0 Endomucin MFS_1 PF07690.16 KFM69265.1 - 2.9e-37 128.4 30.8 2.4e-21 76.0 12.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFM69265.1 - 1.5e-07 31.1 16.3 1.1e-06 28.2 2.3 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 KFM69265.1 - 4.6e-05 22.2 5.4 4.6e-05 22.2 5.4 1.8 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like DUF2065 PF09838.9 KFM69265.1 - 4.1 7.5 9.4 1.4 9.0 0.8 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) Lamp PF01299.17 KFM69267.1 - 1.4e-18 67.2 0.4 1.8e-18 66.8 0.4 1.2 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFM69267.1 - 0.00024 21.0 0.3 0.00038 20.3 0.3 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) MetRS-N PF09635.10 KFM69267.1 - 0.013 16.1 0.1 0.021 15.3 0.1 1.3 1 0 0 1 1 1 0 MetRS-N binding domain TMEM154 PF15102.6 KFM69267.1 - 0.22 11.4 2.2 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family CcmD PF04995.14 KFM69267.1 - 0.27 11.3 2.3 0.48 10.5 2.3 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) HTH_Tnp_Tc3_2 PF01498.18 KFM69268.1 - 4.4e-16 58.9 3.5 5.6e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69268.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69268.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69268.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69268.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Glyco_transf_49 PF13896.6 KFM69269.1 - 5.1e-70 236.4 0.0 6.8e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Tmemb_9 PF05434.11 KFM69269.1 - 0.042 13.8 0.6 0.071 13.0 0.6 1.3 1 0 0 1 1 1 0 TMEM9 ECSCR PF15820.5 KFM69269.1 - 0.16 11.8 0.1 0.76 9.6 0.0 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF4371 PF14291.6 KFM69270.1 - 4e-10 39.8 0.0 7.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF771 PF05595.11 KFM69270.1 - 0.022 14.7 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF771) PepX_C PF08530.10 KFM69270.1 - 0.24 11.3 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Zip PF02535.22 KFM69273.1 - 2.4e-16 59.9 1.9 2.4e-16 59.9 1.9 3.2 2 1 0 2 2 2 1 ZIP Zinc transporter ZIP4_domain PF18292.1 KFM69273.1 - 0.0084 16.1 0.6 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 Zinc transporter ZIP4 domain ZIP4_domain PF18292.1 KFM69274.1 - 1.7e-08 34.6 0.9 2e-08 34.3 0.9 1.1 1 0 0 1 1 1 1 Zinc transporter ZIP4 domain Hexapep PF00132.24 KFM69275.1 - 0.00016 21.3 6.0 0.00054 19.6 0.2 3.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DDE_Tnp_1_7 PF13843.6 KFM69276.1 - 2e-10 40.6 0.1 5e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM69276.1 - 2e-07 31.7 11.5 4.1e-07 30.7 11.5 1.5 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.16 KFM69276.1 - 0.0051 17.1 2.7 0.011 16.0 2.7 1.6 1 0 0 1 1 1 1 C1 domain DUF2318 PF10080.9 KFM69276.1 - 0.07 13.3 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-B_box PF00643.24 KFM69276.1 - 0.094 12.9 6.4 0.17 12.0 6.4 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-CCHC_2 PF13696.6 KFM69276.1 - 0.2 11.5 11.3 0.6 10.0 0.3 2.7 3 0 0 3 3 3 0 Zinc knuckle zf-HIT PF04438.16 KFM69276.1 - 2.8 7.9 8.8 9.2 6.2 8.8 1.8 1 1 0 1 1 1 0 HIT zinc finger DDE_3 PF13358.6 KFM69279.1 - 0.092 12.5 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.6 KFM69280.1 - 0.035 13.9 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69281.1 - 2.6e-16 59.6 2.2 7.4e-16 58.2 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69281.1 - 1.9e-13 50.4 0.0 3.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69281.1 - 3.6e-07 29.9 1.6 8.7e-07 28.6 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69281.1 - 0.0039 16.9 2.1 0.0094 15.7 0.5 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69281.1 - 0.033 14.3 0.4 0.11 12.6 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM69281.1 - 3.3 8.4 15.6 0.16 12.6 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain p450 PF00067.22 KFM69283.1 - 2.7e-26 92.3 0.1 3e-26 92.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM69284.1 - 7.4e-05 21.7 0.0 7.4e-05 21.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM69286.1 - 1.8e-15 56.7 0.0 1.8e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FlbD PF06289.11 KFM69287.1 - 0.04 13.5 0.0 0.054 13.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins p450 PF00067.22 KFM69288.1 - 3.4e-57 194.2 0.1 4.2e-57 193.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM69289.1 - 1.7e-81 274.3 0.0 2e-81 274.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM69290.1 - 9e-78 262.1 0.0 1.1e-77 261.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4848 PF16140.5 KFM69290.1 - 0.1 12.2 0.0 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4848) LPMO_10 PF03067.15 KFM69291.1 - 4e-32 112.5 0.4 5e-32 112.1 0.4 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Chitin_bind_4 PF00379.23 KFM69292.1 - 2e-10 41.0 6.4 2e-10 41.0 6.4 2.3 3 0 0 3 3 3 1 Insect cuticle protein DUF5476 PF17570.2 KFM69292.1 - 0.37 11.2 3.5 5.2 7.5 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5476) Ank_3 PF13606.6 KFM69293.1 - 3.7e-09 36.1 0.0 2.1e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFM69293.1 - 1.8e-08 34.9 0.0 2.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM69293.1 - 1.8e-06 28.4 0.0 3.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM69293.1 - 2.8e-06 27.5 0.0 0.00019 21.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KFM69293.1 - 6.2e-06 26.4 0.0 7.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 KFM69293.1 - 0.0083 16.1 0.1 0.052 13.5 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) HIGH_NTase1_ass PF16581.5 KFM69293.1 - 0.08 12.9 0.2 1.5 8.8 0.2 2.0 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Aminotran_3 PF00202.21 KFM69294.1 - 6.1e-80 268.8 0.0 7.6e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Transposase_1 PF01359.18 KFM69297.1 - 0.0002 21.2 0.1 0.00024 20.9 0.1 1.2 1 0 0 1 1 1 1 Transposase (partial DDE domain) TGFb_propeptide PF00688.18 KFM69298.1 - 2.8e-25 89.5 0.0 4.6e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFM69298.1 - 3e-13 50.6 0.0 6.7e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Porin_3 PF01459.22 KFM69299.1 - 2.8e-77 259.8 3.8 3.1e-77 259.7 3.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin Porin_4 PF13609.6 KFM69299.1 - 0.014 15.2 2.5 0.027 14.3 0.4 2.4 1 1 2 3 3 3 0 Gram-negative porin Qn_am_d_aII PF14930.6 KFM69299.1 - 0.11 12.8 0.1 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II SAM_1 PF00536.30 KFM69300.1 - 1.6e-13 50.9 0.1 2.4e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM69300.1 - 1.4e-05 25.1 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 KFM69300.1 - 0.00011 22.0 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFM69300.1 - 0.16 12.0 0.1 0.45 10.5 0.1 1.7 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain tRNA_int_endo_N PF02778.14 KFM69300.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Ish1 PF10281.9 KFM69300.1 - 0.45 10.8 2.0 0.8 10.1 0.1 2.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein PAP2_C PF14360.6 KFM69301.1 - 0.00013 22.4 0.7 0.00013 22.4 0.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily C-terminal HEAT_2 PF13646.6 KFM69302.1 - 7.4e-28 96.8 0.1 1.8e-12 47.5 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 KFM69302.1 - 7.4e-21 72.7 0.0 0.0045 17.5 0.0 6.7 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KFM69302.1 - 9.2e-09 34.8 2.7 1.3 9.5 0.0 5.6 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 KFM69302.1 - 1.3e-06 28.8 0.2 2 9.0 0.0 5.4 5 1 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 KFM69302.1 - 0.00024 21.2 4.4 0.2 11.7 0.3 4.1 1 1 3 4 4 4 3 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 KFM69302.1 - 0.01 16.2 0.1 20 5.6 0.0 3.7 2 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Caenor_Her-1 PF09232.10 KFM69302.1 - 0.074 13.2 3.4 2.9 8.0 0.1 2.7 2 1 0 2 2 2 0 Caenorhabditis elegans Her-1 zf-H2C2_2 PF13465.6 KFM69303.1 - 2.3e-80 261.7 108.9 8.8e-09 35.4 1.3 14.1 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69303.1 - 1.9e-62 204.4 119.8 1.2e-05 25.5 2.5 13.2 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69303.1 - 3.4e-48 158.1 111.1 0.00023 21.7 2.5 13.2 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM69303.1 - 7.7e-26 89.7 106.7 0.028 14.8 1.1 13.5 13 0 0 13 13 13 13 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM69303.1 - 4e-22 78.0 89.0 0.0088 16.3 0.1 14.0 12 2 1 13 13 13 10 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM69303.1 - 4.7e-17 61.4 46.1 0.062 13.2 0.5 13.2 13 0 0 13 13 13 7 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFM69303.1 - 9e-11 41.3 82.0 0.066 13.0 0.1 13.4 13 0 0 13 13 13 8 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM69303.1 - 2.1e-09 37.2 104.2 0.29 11.2 0.5 15.3 13 4 0 13 13 13 8 C2H2-type zinc finger ADK_lid PF05191.14 KFM69303.1 - 2e-05 24.4 42.2 0.39 10.8 0.7 8.1 5 3 2 7 7 7 5 Adenylate kinase, active site lid TRAF6_Z2 PF18048.1 KFM69303.1 - 0.0015 18.6 3.7 0.022 14.9 0.2 11.8 13 0 0 13 13 12 4 TNF receptor-associated factor 6 zinc finger 2 zf-CHCC PF10276.9 KFM69303.1 - 0.0032 17.5 19.9 10 6.3 0.0 9.3 11 0 0 11 11 11 0 Zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM69303.1 - 0.019 15.0 57.5 2.7 8.1 0.2 12.7 12 1 1 13 13 13 0 Sec23/Sec24 zinc finger zf_UBZ PF18439.1 KFM69303.1 - 0.022 14.4 58.4 8.4 6.1 0.3 12.9 13 0 0 13 13 13 0 Ubiquitin-Binding Zinc Finger BMP2K_C PF15282.6 KFM69303.1 - 0.051 13.4 0.3 7.4 6.4 0.0 2.5 2 0 0 2 2 2 0 BMP-2-inducible protein kinase C-terminus FYVE PF01363.21 KFM69303.1 - 0.16 12.1 73.6 4.4 7.5 10.5 8.0 2 2 4 7 7 7 0 FYVE zinc finger DUF302 PF03625.14 KFM69303.1 - 0.62 10.0 4.6 3.2 7.7 0.0 4.1 6 0 0 6 6 5 0 Domain of unknown function DUF302 BolA PF01722.18 KFM69303.1 - 0.66 10.3 32.1 1.3 9.4 0.6 6.7 3 2 4 7 7 7 0 BolA-like protein BHD_1 PF10403.9 KFM69303.1 - 2 8.3 10.2 21 5.0 0.0 5.7 6 1 0 6 6 5 0 Rad4 beta-hairpin domain 1 zinc_ribbon_15 PF17032.5 KFM69303.1 - 3.1 8.6 58.3 6.4 7.6 2.3 7.0 1 1 4 8 8 8 0 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM69303.1 - 4.5 7.4 59.3 0.65 10.1 8.0 5.9 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM69303.1 - 5.8 7.1 45.8 18 5.5 0.1 11.7 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) Endonuc-MspI PF09208.10 KFM69303.1 - 9.9 5.5 9.1 5.4 6.3 1.9 2.6 1 1 0 2 2 2 0 Restriction endonuclease MspI THAP PF05485.12 KFM69304.1 - 1.9e-20 73.6 0.5 2.5e-20 73.2 0.5 1.2 1 0 0 1 1 1 1 THAP domain PBC PF03792.13 KFM69305.1 - 0.002 17.9 1.2 0.0037 17.0 1.2 1.4 1 0 0 1 1 1 1 PBC domain DUF1168 PF06658.12 KFM69305.1 - 0.021 14.6 3.2 0.021 14.6 3.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) SlyX PF04102.12 KFM69305.1 - 0.023 15.3 1.5 0.042 14.5 1.1 1.7 1 1 0 1 1 1 0 SlyX DUF745 PF05335.13 KFM69305.1 - 0.031 14.0 0.8 0.063 13.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1780 PF08682.10 KFM69305.1 - 0.1 12.3 0.3 0.14 11.8 0.3 1.2 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) T4bSS_IcmS PF12608.8 KFM69305.1 - 0.1 12.9 1.1 0.21 11.9 1.1 1.5 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment HTH_Tnp_Tc3_2 PF01498.18 KFM69306.1 - 7.4e-07 29.3 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Transposase Ig_2 PF13895.6 KFM69307.1 - 0.017 15.5 0.0 0.03 14.6 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM69308.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69308.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69308.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69308.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69308.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ctr PF04145.15 KFM69311.1 - 4.8e-34 118.1 8.5 4.8e-34 118.1 8.5 2.3 2 1 0 2 2 2 1 Ctr copper transporter family TMPIT PF07851.13 KFM69312.1 - 0.17 11.1 7.3 0.3 10.3 7.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein NAD_binding_2 PF03446.15 KFM69312.1 - 0.23 11.6 0.2 0.4 10.8 0.2 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase G6PD_N PF00479.22 KFM69312.1 - 0.51 11.0 3.3 1 10.0 3.3 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain LSDAT_euk PF18139.1 KFM69314.1 - 3.5e-17 62.7 0.1 4.5e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 KFM69314.1 - 0.00036 19.8 0.0 0.00066 19.0 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Adeno_PIX PF03955.14 KFM69314.1 - 0.037 14.2 0.1 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Patatin PF01734.22 KFM69315.1 - 6e-25 88.6 0.0 1.1e-24 87.8 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Pkinase PF00069.25 KFM69316.1 - 7.8e-73 245.1 0.0 1.4e-72 244.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM69316.1 - 4.3e-47 160.6 0.0 6.5e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.18 KFM69316.1 - 3.1e-33 113.7 2.4 1.2e-18 66.9 1.8 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KFM69316.1 - 3.5e-05 23.4 2.7 0.01 15.6 0.5 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM69316.1 - 0.00015 21.6 3.8 0.083 13.0 0.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Kdo PF06293.14 KFM69316.1 - 0.00055 19.4 0.0 0.0016 17.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.6 KFM69316.1 - 0.00085 19.6 0.1 2.2 8.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Kinase-like PF14531.6 KFM69316.1 - 0.0014 18.0 0.0 0.0058 16.0 0.0 2.0 1 1 0 1 1 1 1 Kinase-like TPR_7 PF13176.6 KFM69316.1 - 0.0016 18.3 0.1 1.8 8.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM69316.1 - 0.0024 17.5 1.1 1 9.1 0.1 2.9 2 0 0 2 2 2 2 TPR repeat MAS20 PF02064.15 KFM69316.1 - 0.0098 16.0 0.2 0.41 10.7 0.0 2.4 1 1 0 2 2 2 1 MAS20 protein import receptor TPR_MalT PF17874.1 KFM69316.1 - 0.012 15.0 0.1 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 MalT-like TPR region HEPN PF05168.14 KFM69316.1 - 0.021 15.0 2.8 4.6 7.4 0.1 3.0 2 1 0 2 2 2 0 HEPN domain APH PF01636.23 KFM69316.1 - 0.082 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SPC25 PF06703.11 KFM69318.1 - 0.28 10.9 1.9 0.49 10.2 1.1 1.7 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Phosphodiest PF01663.22 KFM69319.1 - 2.1e-12 47.3 0.1 2.9e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFM69319.1 - 1.6e-07 31.0 0.0 2.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KFM69319.1 - 0.00056 19.3 0.1 0.00085 18.8 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily APH PF01636.23 KFM69321.1 - 8.5e-16 58.6 0.0 1.2e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFM69321.1 - 0.0061 15.9 0.3 0.01 15.2 0.3 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KFM69321.1 - 0.022 14.3 1.9 0.07 12.7 0.6 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Glyco_hydro_31 PF01055.26 KFM69322.1 - 4.3e-35 121.7 0.0 5.6e-34 118.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Chloroplast_duf PF14476.6 KFM69322.1 - 0.062 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Petal formation-expressed KAP PF05804.12 KFM69323.1 - 7.7e-261 867.3 26.1 9.4e-261 867.0 26.1 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 KFM69323.1 - 0.00054 20.0 3.7 0.36 10.9 0.1 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KFM69323.1 - 0.02 14.9 6.1 2.9 8.0 0.0 5.7 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat zf-H2C2_2 PF13465.6 KFM69324.1 - 2.4e-17 62.5 35.3 3.8e-08 33.4 1.7 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69324.1 - 8.6e-17 60.6 38.4 8.5e-06 25.9 1.9 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69324.1 - 5.2e-11 42.4 40.6 0.0004 21.0 1.4 6.1 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM69324.1 - 2.4e-07 30.9 24.2 0.0031 17.8 0.1 5.6 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM69324.1 - 0.00017 21.5 31.1 0.0011 18.9 1.9 5.3 5 0 0 5 5 5 2 C2H2-type zinc finger zf-LYAR PF08790.11 KFM69324.1 - 0.018 14.9 16.9 0.64 10.0 0.9 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger ADK_lid PF05191.14 KFM69324.1 - 0.024 14.6 12.0 0.051 13.6 3.0 3.7 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-BED PF02892.15 KFM69324.1 - 0.088 12.8 28.7 0.24 11.5 1.8 5.3 4 1 1 5 5 5 0 BED zinc finger XPA_N PF01286.18 KFM69324.1 - 0.14 12.2 10.2 5.5 7.1 0.1 4.3 4 0 0 4 4 4 0 XPA protein N-terminal zf_UBZ PF18439.1 KFM69324.1 - 0.19 11.4 0.1 0.19 11.4 0.1 4.4 5 0 0 5 5 4 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFM69324.1 - 0.27 11.7 0.1 0.27 11.7 0.1 4.6 5 0 0 5 5 4 0 Zinc-finger of C2H2 type GAGA PF09237.11 KFM69324.1 - 1.5 8.7 6.2 8.3 6.3 0.0 3.9 3 1 1 4 4 4 0 GAGA factor zf-C2HC_2 PF13913.6 KFM69324.1 - 4.2 7.4 23.9 2.4 8.1 0.3 5.5 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM69324.1 - 6 7.7 15.9 5.9 7.7 0.5 3.5 2 1 1 3 3 3 0 zinc-ribbon family zf-CHCC PF10276.9 KFM69324.1 - 6.2 7.0 14.4 6.9 6.8 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger domain zf-C2HE PF16278.5 KFM69324.1 - 6.6 7.3 22.2 4.3 7.9 1.2 5.4 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 KFM69324.1 - 8.3 6.4 15.0 16 5.5 1.0 4.8 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_2 PF13465.6 KFM69326.1 - 9.8e-32 108.0 39.4 5.5e-08 32.9 1.7 6.0 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69326.1 - 2e-27 94.1 40.2 3.3e-06 27.3 1.3 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69326.1 - 1.1e-21 75.6 38.4 7.4e-05 23.3 1.4 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM69326.1 - 1.6e-15 56.6 29.9 0.0035 17.3 2.2 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM69326.1 - 3.1e-14 52.8 16.7 0.0032 17.7 0.1 5.5 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM69326.1 - 7.9e-09 35.6 27.7 0.00032 21.0 0.6 5.1 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KFM69326.1 - 1.1e-05 25.2 21.7 0.67 9.9 0.3 5.5 5 0 0 5 5 5 3 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM69326.1 - 3.3e-05 23.4 15.3 0.29 10.8 0.1 5.3 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 KFM69326.1 - 9.2e-05 22.3 18.8 0.032 14.1 2.9 3.6 2 1 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_3rep PF18868.1 KFM69326.1 - 0.00023 21.9 16.9 0.049 14.3 2.0 4.4 1 1 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats HNH_5 PF14279.6 KFM69326.1 - 0.00026 20.8 14.4 1.7 8.6 0.9 5.1 3 2 1 4 4 4 2 HNH endonuclease Ta0938 PF11494.8 KFM69326.1 - 0.00031 21.0 0.8 0.075 13.3 0.1 2.7 2 1 0 2 2 2 1 Ta0938 zf-C2H2_11 PF16622.5 KFM69326.1 - 0.00032 20.4 22.5 1.2 8.9 0.4 5.3 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-BED PF02892.15 KFM69326.1 - 0.00032 20.7 25.8 0.13 12.3 2.4 5.1 2 1 3 5 5 5 2 BED zinc finger Prok-RING_1 PF14446.6 KFM69326.1 - 0.00046 20.0 14.4 4.4 7.3 0.1 5.2 4 1 0 4 4 4 0 Prokaryotic RING finger family 1 zinc_ribbon_15 PF17032.5 KFM69326.1 - 0.00065 20.4 11.4 0.3 11.9 1.5 3.0 1 1 2 3 3 3 3 zinc-ribbon family zf-AN1 PF01428.16 KFM69326.1 - 0.00079 19.5 20.4 2.3 8.5 1.0 5.3 4 1 1 5 5 5 2 AN1-like Zinc finger PyrI_C PF02748.15 KFM69326.1 - 0.0015 18.3 11.8 0.57 10.1 0.1 4.9 4 1 1 5 5 5 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 KFM69326.1 - 0.0023 18.0 20.8 1.3 9.2 0.6 4.4 2 2 3 5 5 5 3 Zinc ribbon domain zf-MYND PF01753.18 KFM69326.1 - 0.0023 18.0 9.4 0.0088 16.1 1.1 3.5 2 2 0 2 2 2 1 MYND finger GAGA PF09237.11 KFM69326.1 - 0.0029 17.4 7.1 0.92 9.4 0.4 3.6 2 2 2 4 4 4 2 GAGA factor zf-Di19 PF05605.12 KFM69326.1 - 0.003 17.8 24.1 0.009 16.3 4.5 4.0 2 1 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.9 KFM69326.1 - 0.0057 16.7 13.8 0.18 11.9 0.3 4.5 5 0 0 5 5 5 2 Zinc-finger domain zf-C2H2_8 PF15909.5 KFM69326.1 - 0.0062 16.8 17.7 0.1 12.9 4.5 2.8 1 1 2 3 3 3 2 C2H2-type zinc ribbon HypA PF01155.19 KFM69326.1 - 0.0092 16.0 10.7 0.31 11.1 3.6 2.9 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HNH PF01844.23 KFM69326.1 - 0.012 15.8 21.1 0.76 10.0 0.7 5.2 5 0 0 5 5 5 0 HNH endonuclease BolA PF01722.18 KFM69326.1 - 0.018 15.3 9.6 2.4 8.5 0.3 3.7 1 1 1 3 3 3 0 BolA-like protein Zf_RING PF16744.5 KFM69326.1 - 0.024 14.7 16.8 3.3 7.9 0.5 4.9 1 1 4 5 5 5 0 KIAA1045 RING finger XPA_N PF01286.18 KFM69326.1 - 0.04 14.0 17.8 3.3 7.8 0.6 5.1 5 0 0 5 5 5 0 XPA protein N-terminal FYVE PF01363.21 KFM69326.1 - 0.041 14.0 22.6 0.65 10.2 4.3 3.6 1 1 2 3 3 3 0 FYVE zinc finger YhfH PF14149.6 KFM69326.1 - 0.045 13.7 9.2 8.1 6.5 0.2 4.1 3 1 1 4 4 4 0 YhfH-like protein zf-LYAR PF08790.11 KFM69326.1 - 0.051 13.5 18.7 2.5 8.1 1.4 5.1 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 KFM69326.1 - 0.061 13.5 15.3 6.9 6.9 0.1 5.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Elf1 PF05129.13 KFM69326.1 - 0.068 13.2 16.3 0.057 13.5 2.2 3.3 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like CpXC PF14353.6 KFM69326.1 - 0.07 13.2 13.2 21 5.2 1.8 4.7 1 1 3 4 4 4 0 CpXC protein zinc-ribbons_6 PF07191.12 KFM69326.1 - 0.13 12.2 14.1 5.5 7.0 2.3 4.0 1 1 2 4 4 4 0 zinc-ribbons Cript PF10235.9 KFM69326.1 - 0.15 12.7 16.4 1.9 9.1 4.0 3.6 1 1 3 4 4 4 0 Microtubule-associated protein CRIPT zf-C2H2_2 PF12756.7 KFM69326.1 - 0.16 12.3 24.4 1.8 9.0 0.2 5.0 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFM69326.1 - 0.19 12.2 24.5 2 8.9 1.7 5.0 1 1 4 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger FYDLN_acid PF09538.10 KFM69326.1 - 0.21 12.3 8.9 53 4.6 0.1 4.3 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) LIM PF00412.22 KFM69326.1 - 0.34 11.2 18.9 12 6.2 1.4 4.3 1 1 3 4 4 4 0 LIM domain DZR PF12773.7 KFM69326.1 - 0.52 10.4 17.3 52 4.0 17.3 3.0 1 1 0 1 1 1 0 Double zinc ribbon ADK_lid PF05191.14 KFM69326.1 - 0.56 10.2 14.0 4.7 7.3 1.2 4.2 3 1 1 4 4 4 0 Adenylate kinase, active site lid Yippee-Mis18 PF03226.14 KFM69326.1 - 0.78 10.0 10.1 2.5 8.3 0.3 3.0 1 1 3 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cys_rich_CPXG PF14255.6 KFM69326.1 - 1.1 9.2 9.2 6.1 6.8 1.0 4.0 3 2 1 4 4 4 0 Cysteine-rich CPXCG Zn_ribbon_recom PF13408.6 KFM69326.1 - 1.2 9.7 17.0 47 4.6 0.2 4.5 3 1 2 5 5 5 0 Recombinase zinc beta ribbon domain Evr1_Alr PF04777.13 KFM69326.1 - 1.6 9.2 16.2 9.1 6.8 0.4 4.3 1 1 2 3 3 3 0 Erv1 / Alr family Ribosomal_L28 PF00830.19 KFM69326.1 - 2.1 8.6 11.9 4.1 7.7 0.4 4.4 4 1 0 4 4 4 0 Ribosomal L28 family DUF3268 PF11672.8 KFM69326.1 - 2.6 8.4 10.7 6 7.2 2.2 3.3 1 1 3 4 4 4 0 zinc-finger-containing domain HTH_Tnp_Tc3_2 PF01498.18 KFM69327.1 - 4.8e-16 58.8 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69327.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69327.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69327.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69327.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM69328.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69328.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69328.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69328.1 - 0.0011 18.6 0.5 0.0074 16.1 0.6 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69328.1 - 0.011 15.9 0.3 0.088 12.9 0.4 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM69328.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain MADF_DNA_bdg PF10545.9 KFM69329.1 - 3.3e-21 75.4 0.7 3.3e-21 75.4 0.7 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 KFM69329.1 - 3.6e-09 36.3 0.5 6.3e-09 35.5 0.5 1.4 1 0 0 1 1 1 1 BESS motif Myb_DNA-bind_5 PF13873.6 KFM69329.1 - 0.042 13.9 2.8 0.056 13.5 0.6 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain zf-H2C2_2 PF13465.6 KFM69330.1 - 1.7e-86 281.1 94.4 2.8e-09 37.0 0.7 12.9 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69330.1 - 2.8e-55 181.8 121.5 1.5e-05 25.2 3.8 12.4 13 0 0 13 13 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69330.1 - 1.5e-39 131.2 113.8 0.0012 19.6 2.1 12.5 13 0 0 13 13 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM69330.1 - 9.3e-36 121.2 106.3 0.00087 19.6 1.0 12.5 13 0 0 13 13 12 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM69330.1 - 1.5e-21 76.1 78.4 0.014 15.7 0.4 12.3 12 0 0 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM69330.1 - 1.4e-18 66.3 72.5 0.022 14.5 0.2 13.4 13 1 0 13 13 13 9 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM69330.1 - 3.3e-18 65.1 83.7 0.073 12.9 2.5 12.3 12 0 0 12 12 12 11 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM69330.1 - 6.3e-16 57.9 96.8 0.004 17.1 2.0 12.2 12 0 0 12 12 12 9 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM69330.1 - 1.7e-09 37.6 40.0 1.7 8.7 0.2 11.4 9 3 3 12 12 12 4 Sec23/Sec24 zinc finger BolA PF01722.18 KFM69330.1 - 2.6e-09 37.2 27.2 0.18 12.1 0.1 8.3 1 1 5 8 8 8 4 BolA-like protein zf-C2HC_2 PF13913.6 KFM69330.1 - 4.2e-05 23.3 54.9 0.29 11.1 3.1 11.8 12 0 0 12 12 12 3 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM69330.1 - 0.028 15.2 58.6 0.61 10.9 0.9 6.3 3 1 2 6 6 6 0 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM69330.1 - 0.15 12.0 57.6 4.9 7.1 0.5 11.8 2 2 10 12 12 12 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM69330.1 - 0.23 11.3 31.0 4.5 7.2 0.0 8.7 3 3 7 10 10 10 0 GAGA factor Baculo_IE-1 PF05290.11 KFM69330.1 - 0.26 11.2 47.6 8 6.4 0.2 8.2 1 1 4 6 6 6 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_2 PF12756.7 KFM69330.1 - 0.44 10.9 94.9 1.3 9.4 1.7 11.7 1 1 11 12 12 12 0 C2H2 type zinc-finger (2 copies) eRF1_2 PF03464.15 KFM69330.1 - 0.61 10.4 5.3 12 6.2 0.0 3.7 4 0 0 4 4 4 0 eRF1 domain 2 zf-DBF PF07535.12 KFM69330.1 - 2.6 8.3 65.3 7.4 6.8 0.2 12.1 11 1 1 12 12 12 0 DBF zinc finger C1_1 PF00130.22 KFM69330.1 - 4.7 7.2 77.6 0.71 9.8 0.8 9.9 3 3 6 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DDE_3 PF13358.6 KFM69331.1 - 2.9e-16 59.6 0.1 3.5e-15 56.0 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69331.1 - 1.5e-10 41.1 1.0 3e-10 40.2 1.0 1.5 1 0 0 1 1 1 1 Transposase Guanylate_kin PF00625.21 KFM69332.1 - 6.6e-61 205.2 0.0 1.1e-60 204.4 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KFM69332.1 - 3.6e-11 42.6 0.0 7.7e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 KFM69332.1 - 7.7e-10 39.0 0.1 1.5e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 KFM69332.1 - 6.9e-09 35.2 0.9 4.6e-08 32.5 0.9 2.3 1 1 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 KFM69332.1 - 2.7e-05 23.9 0.1 6.2e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KFM69332.1 - 0.0015 18.4 0.1 0.004 17.0 0.1 1.7 1 1 0 1 1 1 1 Variant SH3 domain DDE_Tnp_1_2 PF13586.6 KFM69333.1 - 0.024 15.0 0.2 0.059 13.7 0.1 1.7 1 1 0 1 1 1 0 Transposase DDE domain DUF1451 PF07295.11 KFM69334.1 - 0.0042 17.1 7.1 0.0043 17.1 7.1 1.0 1 0 0 1 1 1 1 Zinc-ribbon containing domain DUF5424 PF17462.2 KFM69334.1 - 0.12 12.3 0.3 0.13 12.2 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5424) Strep_SA_rep PF06696.11 KFM69334.1 - 0.16 12.0 9.7 0.75 9.9 0.3 3.4 3 2 1 4 4 4 0 Streptococcal surface antigen repeat Myb_Cef PF11831.8 KFM69334.1 - 0.16 11.5 8.5 0.14 11.7 7.0 1.7 1 1 0 1 1 1 0 pre-mRNA splicing factor component DUF883 PF05957.13 KFM69334.1 - 0.4 11.3 6.2 0.47 11.1 6.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KFM69334.1 - 2.7 8.6 6.8 3.8 8.1 6.8 1.4 1 0 0 1 1 1 0 YtxH-like protein DUF5641 PF18701.1 KFM69335.1 - 4.8e-20 71.5 0.2 7.7e-20 70.9 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Rieske PF00355.26 KFM69336.1 - 2.4e-16 59.4 0.0 5e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KFM69336.1 - 0.0027 17.6 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain SMC_N PF02463.19 KFM69337.1 - 8.6e-28 97.3 6.6 2.1e-27 96.0 6.5 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFM69337.1 - 3.6e-16 59.5 0.0 1.1e-15 58.0 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFM69337.1 - 7e-06 26.1 0.1 7e-06 26.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KFM69337.1 - 0.22 12.0 18.4 4.9e+02 1.2 18.4 3.5 1 1 0 1 1 1 0 ABC transporter FGGY_N PF00370.21 KFM69338.1 - 2.9e-18 66.3 0.1 9.9e-18 64.6 0.1 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Raco_middle PF17651.1 KFM69338.1 - 0.0035 17.0 0.2 0.0054 16.4 0.2 1.3 1 0 0 1 1 1 1 RACo middle region BcrAD_BadFG PF01869.20 KFM69338.1 - 0.028 13.9 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.21 KFM69338.1 - 0.039 13.9 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Hexokinase DAO PF01266.24 KFM69339.1 - 4.1e-07 29.9 0.0 4.4e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KFM69340.1 - 3.6e-32 112.3 0.0 4.2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM69340.1 - 0.0011 18.3 0.1 0.0055 16.0 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM69340.1 - 0.0018 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFM69340.1 - 0.0057 15.9 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KFM69340.1 - 0.008 16.7 0.2 0.59 10.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFM69340.1 - 0.016 14.5 0.0 0.037 13.3 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF1948 PF09185.10 KFM69340.1 - 0.029 14.3 0.2 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1948) ApbA PF02558.16 KFM69340.1 - 0.031 13.9 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 KFM69340.1 - 0.058 12.7 0.0 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KFM69340.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C2H2 PF00096.26 KFM69341.1 - 3.5e-14 52.3 21.7 1.3e-05 25.4 1.6 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM69341.1 - 6.7e-12 45.3 18.0 2.7e-05 24.4 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM69341.1 - 9.3e-11 41.6 18.8 9.4e-05 22.9 1.2 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM69341.1 - 2.7e-08 33.9 14.9 0.00017 21.9 1.1 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM69341.1 - 1.5e-06 28.3 11.6 0.0016 18.7 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFM69341.1 - 0.00011 22.6 13.1 0.032 14.7 0.8 3.0 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFM69341.1 - 0.00038 20.7 11.8 0.4 11.0 0.5 3.0 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM69341.1 - 0.00058 19.6 14.6 0.0041 16.8 6.7 3.5 4 0 0 4 4 4 2 C2H2-type zinc-finger domain Elf1 PF05129.13 KFM69341.1 - 0.001 19.1 6.9 0.0076 16.3 0.9 2.1 1 1 1 2 2 2 2 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.6 KFM69341.1 - 0.016 15.2 1.0 0.016 15.2 1.0 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger IQ_SEC7_PH PF16453.5 KFM69341.1 - 0.022 14.7 0.6 0.029 14.4 0.6 1.2 1 0 0 1 1 1 0 PH domain zf-BED PF02892.15 KFM69341.1 - 0.044 13.8 16.2 0.29 11.2 1.0 3.1 1 1 2 3 3 3 0 BED zinc finger zf-MYST PF17772.1 KFM69341.1 - 0.071 12.7 7.1 0.66 9.6 0.1 2.5 2 1 0 2 2 2 0 MYST family zinc finger domain PriA_CRR PF18319.1 KFM69341.1 - 0.091 12.8 2.0 0.091 12.8 2.0 2.6 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Endonuclease_7 PF02945.15 KFM69341.1 - 0.39 10.7 5.8 0.22 11.5 1.4 2.0 1 1 1 2 2 2 0 Recombination endonuclease VII DUF2256 PF10013.9 KFM69341.1 - 0.75 10.0 5.0 4 7.6 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 KFM69341.1 - 1 9.2 13.4 0.19 11.5 1.5 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KFM69342.1 - 3.1e-17 62.1 11.7 9.6e-09 35.3 2.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69342.1 - 7.2e-09 35.6 15.1 0.00013 22.2 5.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69342.1 - 4.4e-08 33.3 13.4 0.00024 21.7 1.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM69342.1 - 5.3e-08 33.0 11.3 0.00035 20.9 2.9 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM69342.1 - 3.2e-05 24.1 7.9 0.029 14.7 1.4 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM69342.1 - 0.00012 22.0 8.8 0.083 12.9 3.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM69342.1 - 0.00051 19.7 5.3 0.026 14.3 0.6 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM69342.1 - 0.0023 17.9 2.4 1.2 9.3 0.1 2.1 1 1 1 2 2 2 2 Sec23/Sec24 zinc finger zinc_ribbon_15 PF17032.5 KFM69342.1 - 0.007 17.1 1.1 0.0078 16.9 1.1 1.0 1 0 0 1 1 1 1 zinc-ribbon family zf-MYST PF17772.1 KFM69342.1 - 0.0081 15.8 3.5 0.54 9.9 0.3 2.1 2 0 0 2 2 2 2 MYST family zinc finger domain Zf_RING PF16744.5 KFM69342.1 - 0.022 14.9 3.5 1 9.5 0.2 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger BolA PF01722.18 KFM69342.1 - 0.035 14.4 0.8 0.42 10.9 0.2 1.9 1 1 1 2 2 2 0 BolA-like protein zf-CCHC_2 PF13696.6 KFM69342.1 - 0.08 12.8 4.2 2.2 8.2 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_2 PF12756.7 KFM69342.1 - 0.16 12.3 5.9 0.61 10.4 1.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM69342.1 - 0.43 10.5 0.3 0.43 10.5 0.3 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KFM69342.1 - 0.52 10.8 8.9 0.43 11.0 2.1 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.21 KFM69342.1 - 5.3 7.2 9.5 13 6.0 1.8 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2 PF00096.26 KFM69343.1 - 2.1e-10 40.4 8.6 7.2e-08 32.5 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM69343.1 - 4.3e-10 39.6 2.5 4.3e-10 39.6 2.5 1.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM69343.1 - 1.5e-07 31.7 7.9 2.1e-05 24.9 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM69343.1 - 9.8e-07 29.0 2.3 0.008 16.5 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM69343.1 - 2e-05 24.7 3.3 0.017 15.4 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM69343.1 - 0.00095 19.1 10.4 0.096 12.7 1.9 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM69343.1 - 0.0042 17.1 2.2 0.058 13.4 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM69343.1 - 0.0096 15.7 1.9 0.021 14.6 0.1 1.9 1 1 1 2 2 2 1 GAGA factor zinc-ribbons_6 PF07191.12 KFM69343.1 - 0.012 15.6 0.5 0.014 15.4 0.5 1.2 1 0 0 1 1 1 0 zinc-ribbons DUF2256 PF10013.9 KFM69343.1 - 0.012 15.8 3.0 0.45 10.7 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) LIM PF00412.22 KFM69343.1 - 0.015 15.5 5.0 0.12 12.6 0.3 2.0 1 1 1 2 2 2 0 LIM domain zf-MYST PF17772.1 KFM69343.1 - 0.028 14.0 0.8 0.06 13.0 0.0 1.8 1 1 1 2 2 2 0 MYST family zinc finger domain C1_4 PF07975.12 KFM69343.1 - 0.03 14.6 2.5 0.045 14.0 2.3 1.4 1 1 0 1 1 1 0 TFIIH C1-like domain Prok-RING_1 PF14446.6 KFM69343.1 - 0.037 13.9 2.0 2.1 8.3 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 KFM69343.1 - 0.041 14.2 2.9 0.93 9.9 0.2 2.1 1 1 1 2 2 2 0 C1 domain zf_UBZ PF18439.1 KFM69343.1 - 0.047 13.3 3.1 0.68 9.6 0.4 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HNH PF01844.23 KFM69343.1 - 0.053 13.7 2.1 0.91 9.8 0.1 2.1 2 0 0 2 2 2 0 HNH endonuclease zf-H2C2_5 PF13909.6 KFM69343.1 - 0.055 13.2 1.1 0.055 13.2 1.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-CHY PF05495.12 KFM69343.1 - 0.064 13.8 3.5 0.16 12.4 0.3 2.0 1 1 1 2 2 2 0 CHY zinc finger Zf_RING PF16744.5 KFM69343.1 - 0.1 12.7 2.0 5.9 7.1 2.0 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KFM69343.1 - 0.12 12.7 0.2 0.12 12.7 0.2 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-HIT PF04438.16 KFM69343.1 - 0.25 11.2 3.7 7.2 6.6 0.3 2.1 2 0 0 2 2 2 0 HIT zinc finger XPA_N PF01286.18 KFM69343.1 - 0.27 11.3 4.1 7 6.8 0.3 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2HE PF16278.5 KFM69343.1 - 0.31 11.5 5.0 2.8 8.4 0.5 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF4764 PF15961.5 KFM69343.1 - 0.94 8.1 4.9 1.7 7.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) HTH_48 PF17906.1 KFM69344.1 - 1.4e-05 25.1 0.2 2.4e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_29 PF13551.6 KFM69344.1 - 0.015 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix zf-H2C2_2 PF13465.6 KFM69345.1 - 3.1e-11 43.2 23.3 1.4e-08 34.8 1.4 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69345.1 - 3.5e-11 42.9 29.2 1.1e-06 28.7 2.6 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69345.1 - 6.9e-07 29.6 25.9 0.0064 17.2 2.0 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM69345.1 - 1.8e-06 28.1 22.1 0.00022 21.5 1.2 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM69345.1 - 0.0022 18.2 0.4 0.0022 18.2 0.4 4.0 3 2 0 3 3 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM69345.1 - 0.0049 16.6 2.2 0.0049 16.6 2.2 3.6 3 1 0 3 3 3 1 C2H2-type zinc-finger domain Spt46 PF17734.1 KFM69345.1 - 0.005 16.7 3.9 0.0062 16.4 3.5 1.4 1 1 0 1 1 1 1 Spermatogenesis-associated protein 46 zf_C2H2_ZHX PF18387.1 KFM69345.1 - 0.043 13.5 2.6 0.043 13.5 2.6 2.3 2 2 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 KFM69345.1 - 0.082 13.4 14.6 0.24 11.9 4.0 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 KFM69345.1 - 0.18 11.7 3.4 0.28 11.0 0.1 2.1 1 1 1 2 2 2 0 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM69345.1 - 0.2 11.7 12.8 12 6.1 7.2 3.6 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger C2-set_2 PF08205.12 KFM69345.1 - 0.32 11.1 4.1 0.87 9.7 3.6 1.9 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain TRAF6_Z2 PF18048.1 KFM69345.1 - 0.37 10.9 0.3 0.37 10.9 0.3 2.9 2 1 1 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Elf1 PF05129.13 KFM69345.1 - 0.45 10.6 12.9 3.7 7.7 5.0 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zf_RING PF16744.5 KFM69345.1 - 3 8.0 10.8 12 6.1 4.4 2.9 1 1 2 3 3 3 0 KIAA1045 RING finger zf-C2H2_11 PF16622.5 KFM69345.1 - 4.3 7.2 16.8 0.29 10.9 2.7 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFM69345.1 - 6.6 7.1 18.6 0.74 10.2 2.7 2.9 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM69345.1 - 6.9 6.9 12.4 3.6 7.8 0.2 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF1854 PF08909.11 KFM69346.1 - 0.15 11.9 0.0 0.88 9.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1854) zf-C2H2 PF00096.26 KFM69347.1 - 7e-08 32.5 1.9 1.1e-07 31.9 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69347.1 - 1.6e-05 25.3 1.0 2.4e-05 24.8 1.0 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM69347.1 - 6.4e-05 23.2 0.9 6.4e-05 23.2 0.9 1.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-met PF12874.7 KFM69347.1 - 0.0012 19.1 0.5 0.0012 19.1 0.5 1.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM69347.1 - 0.005 16.8 2.3 0.0086 16.1 2.3 1.5 1 1 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM69347.1 - 0.018 15.4 0.5 0.023 15.0 0.5 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 KFM69347.1 - 0.079 12.6 0.2 0.086 12.5 0.2 1.1 1 0 0 1 1 1 0 MYST family zinc finger domain Atg14 PF10186.9 KFM69347.1 - 0.087 11.9 0.5 0.077 12.1 0.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PSCyt1 PF07635.11 KFM69347.1 - 0.19 12.4 0.9 0.98 10.1 0.2 1.9 2 0 0 2 2 2 0 Planctomycete cytochrome C PDZ PF00595.24 KFM69348.1 - 5.1e-21 74.8 0.4 8.4e-21 74.1 0.4 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM69348.1 - 7.5e-12 44.9 0.0 1.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 KFM69348.1 - 7.9e-08 31.8 0.3 3e-07 30.0 0.3 2.0 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM69348.1 - 1.2e-07 31.3 0.0 2.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 KFM69348.1 - 5.1e-05 23.5 0.0 0.00028 21.1 0.0 2.0 2 0 0 2 2 2 1 PDZ domain SH3_9 PF14604.6 KFM69348.1 - 0.015 15.1 0.1 0.037 13.9 0.1 1.7 1 0 0 1 1 1 0 Variant SH3 domain Guanylate_kin PF00625.21 KFM69349.1 - 1.4e-63 213.9 0.1 1.6e-63 213.7 0.1 1.0 1 0 0 1 1 1 1 Guanylate kinase Folate_rec PF03024.14 KFM69350.1 - 7.9e-44 149.6 26.8 1e-43 149.2 26.8 1.1 1 0 0 1 1 1 1 Folate receptor family Glycoprot_B_PH2 PF17417.2 KFM69351.1 - 0.0074 16.6 0.0 0.0096 16.2 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B PH-like domain Sema PF01403.19 KFM69352.1 - 1.2e-21 77.0 0.0 2e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFM69352.1 - 3.4e-08 33.9 5.6 5.8e-08 33.1 5.3 1.6 1 1 0 1 1 1 1 Plexin repeat stn_TNFRSF12A PF12191.8 KFM69352.1 - 0.063 13.5 0.8 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DHHC PF01529.20 KFM69352.1 - 1.1 9.4 3.1 2.1 8.4 2.2 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase Sema PF01403.19 KFM69353.1 - 2.7e-78 263.7 0.5 3e-78 263.6 0.5 1.0 1 0 0 1 1 1 1 Sema domain DRMBL PF07522.14 KFM69358.1 - 6.3e-12 45.7 1.5 3.3e-11 43.4 1.5 2.0 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 KFM69358.1 - 0.00029 20.7 0.1 0.00059 19.7 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Ribul_P_3_epim PF00834.19 KFM69361.1 - 2.9e-68 229.2 0.0 3.4e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KFM69361.1 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.6 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.14 KFM69361.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 KFM69361.1 - 0.021 14.4 0.1 0.031 13.9 0.1 1.3 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Linker_histone PF00538.19 KFM69362.1 - 0.12 12.7 0.1 0.98 9.8 0.0 2.0 2 0 0 2 2 2 0 linker histone H1 and H5 family Chromo PF00385.24 KFM69365.1 - 4.1e-15 55.4 1.6 1.2e-14 54.0 1.6 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CXXC PF02008.20 KFM69365.1 - 6.1e-08 32.6 11.5 6.1e-08 32.6 11.5 6.0 6 0 0 6 6 6 1 CXXC zinc finger domain zf-C2H2 PF00096.26 KFM69365.1 - 1.3e-07 31.6 119.0 0.0017 18.7 2.2 17.3 18 0 0 18 18 18 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69365.1 - 1.6e-05 25.4 141.2 0.003 18.2 1.2 18.5 20 0 0 20 20 20 10 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM69365.1 - 0.0024 18.2 91.6 0.0035 17.6 2.3 9.4 5 3 6 11 11 11 6 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM69365.1 - 0.0028 18.0 0.5 0.0028 18.0 0.5 14.0 16 0 0 16 16 16 5 Zinc-finger double domain p450 PF00067.22 KFM69367.1 - 6.2e-10 38.4 0.0 7.2e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_Tnp_Tc3_2 PF01498.18 KFM69368.1 - 2.2e-16 59.8 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69368.1 - 3.9e-15 55.9 0.0 6.5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69369.1 - 2.6e-16 59.6 2.2 5.8e-16 58.5 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69369.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69369.1 - 2.4e-05 24.0 0.7 0.00012 21.8 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Ras PF00071.22 KFM69370.1 - 9.4e-46 155.4 0.2 2.5e-45 154.0 0.0 1.6 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFM69370.1 - 6e-24 84.6 0.0 1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM69370.1 - 2.6e-12 46.5 0.2 9.5e-10 38.2 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM69370.1 - 2.7e-06 27.0 0.5 0.0002 21.0 0.2 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFM69370.1 - 7.2e-05 22.3 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFM69370.1 - 0.00088 19.2 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFM69370.1 - 0.00095 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFM69370.1 - 0.068 13.5 0.1 0.16 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFM69370.1 - 0.094 13.1 0.1 1.1 9.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFM69370.1 - 0.12 12.3 0.5 0.67 9.8 0.1 2.1 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 KFM69370.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 KFM69371.1 - 3.8e-20 72.1 0.1 5.7e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM69371.1 - 0.0002 21.5 0.1 0.00056 20.1 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SUZ PF12752.7 KFM69371.1 - 0.071 13.9 0.2 0.12 13.1 0.2 1.4 1 0 0 1 1 1 0 SUZ domain IMPa_N_2 PF18650.1 KFM69371.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain COesterase PF00135.28 KFM69372.1 - 1.4e-19 70.4 0.1 1.4e-19 70.3 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM69372.1 - 0.0002 21.3 0.0 0.0002 21.3 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold HTH_Tnp_Tc3_2 PF01498.18 KFM69373.1 - 1.7e-16 60.2 0.2 3.4e-16 59.2 0.2 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69373.1 - 4.9e-05 23.9 1.6 4.9e-05 23.9 1.6 2.2 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM69373.1 - 0.00099 19.0 0.1 0.077 12.9 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_3 PF01381.22 KFM69373.1 - 0.0033 17.5 0.1 0.24 11.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM69373.1 - 0.0047 16.9 0.2 0.082 12.9 0.0 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain PAX PF00292.18 KFM69373.1 - 0.027 14.4 0.0 0.048 13.6 0.0 1.5 1 1 0 1 1 1 0 'Paired box' domain HTH_28 PF13518.6 KFM69373.1 - 0.051 13.7 1.5 0.64 10.2 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 KFM69373.1 - 0.1 13.1 0.3 6.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 KFM69373.1 - 0.18 11.4 0.4 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM69373.1 - 3 7.7 5.6 3.2 7.7 0.1 2.9 3 0 0 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM69374.1 - 1.3e-16 60.7 0.1 5.7e-15 55.4 0.0 2.6 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69374.1 - 7.4e-16 58.2 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69374.1 - 0.0011 19.6 1.6 0.0011 19.6 1.6 2.7 2 1 0 2 2 2 1 Homeodomain-like domain ECH_1 PF00378.20 KFM69376.1 - 7.8e-41 140.0 0.2 1.1e-40 139.5 0.2 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM69376.1 - 7.8e-25 88.1 0.0 1e-24 87.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH_N PF02737.18 KFM69376.1 - 4.2e-11 43.1 0.8 1e-10 41.8 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFM69376.1 - 0.0096 16.1 0.4 0.15 12.2 0.1 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFM69376.1 - 0.12 11.9 1.3 0.5 9.9 0.1 2.3 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lipoprotein_10 PF03202.13 KFM69377.1 - 0.19 12.2 3.0 1 9.8 3.0 2.3 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region DUF1090 PF06476.12 KFM69377.1 - 0.39 10.8 4.5 1 9.5 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) HTH_Tnp_Tc3_2 PF01498.18 KFM69379.1 - 2.1e-16 59.9 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69379.1 - 7.7e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Abi_HHR PF07815.14 KFM69380.1 - 9.3e-35 118.6 0.7 2.1e-34 117.5 0.7 1.6 1 0 0 1 1 1 1 Abl-interactor HHR SH3_9 PF14604.6 KFM69380.1 - 1.1e-17 63.6 0.5 3.1e-16 59.0 0.3 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFM69380.1 - 9.5e-15 54.0 0.2 1.7e-14 53.2 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM69380.1 - 1.8e-11 43.5 0.8 8.9e-11 41.3 0.1 2.4 2 1 1 3 3 3 1 Variant SH3 domain ATP-synt_ab_Xtn PF16886.5 KFM69380.1 - 0.026 14.4 0.1 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 ATPsynthase alpha/beta subunit N-term extension CNTF PF01110.17 KFM69380.1 - 0.048 13.0 0.3 0.075 12.4 0.3 1.3 1 0 0 1 1 1 0 Ciliary neurotrophic factor SDF PF00375.18 KFM69381.1 - 4.2e-57 193.9 11.9 4.6e-57 193.8 11.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KFM69382.1 - 2.1e-32 112.6 2.7 2.7e-32 112.3 2.7 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Tetraspanin PF00335.20 KFM69382.1 - 0.027 14.2 0.3 0.092 12.4 0.1 1.9 2 0 0 2 2 2 0 Tetraspanin family DUF4064 PF13273.6 KFM69382.1 - 1.9 8.8 8.0 8 6.8 7.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ECH_1 PF00378.20 KFM69383.1 - 3.3e-35 121.6 0.1 6.9e-35 120.6 0.1 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM69383.1 - 1.9e-20 73.6 0.5 1.9e-20 73.6 0.5 2.5 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase IMUP PF15761.5 KFM69384.1 - 0.026 15.2 3.6 0.027 15.1 3.6 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein PMSR PF01625.21 KFM69385.1 - 3.8e-37 127.8 0.1 6.5e-37 127.1 0.1 1.3 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HTH_Tnp_Tc3_2 PF01498.18 KFM69386.1 - 4.3e-16 58.9 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69386.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69386.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69386.1 - 0.0021 17.8 0.6 0.0076 16.0 0.6 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69386.1 - 1.9 9.2 15.6 0.12 13.0 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM69387.1 - 4.3e-16 58.9 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69387.1 - 1.2e-13 51.0 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69387.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69387.1 - 0.0026 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69387.1 - 2.1 9.0 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Homeodomain PF00046.29 KFM69388.1 - 5.5e-22 77.4 2.0 5.5e-22 77.4 2.0 1.5 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFM69388.1 - 0.00048 20.0 0.6 0.0012 18.7 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain Pilt PF15453.6 KFM69388.1 - 0.018 14.5 0.0 0.019 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Homez PF11569.8 KFM69388.1 - 0.03 13.8 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez FliG_C PF01706.16 KFM69388.1 - 0.077 13.2 0.5 0.14 12.3 0.5 1.4 1 1 0 1 1 1 0 FliG C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM69389.1 - 1.2e-06 28.6 0.3 1.4e-06 28.4 0.3 1.1 1 0 0 1 1 1 1 Transposase BRCT_3 PF18428.1 KFM69389.1 - 0.026 14.6 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Glyco_transf_92 PF01697.27 KFM69391.1 - 3.3e-31 108.9 0.8 3.3e-31 108.9 0.8 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFM69391.1 - 0.00021 21.7 0.1 0.0013 19.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Tissue_fac PF01108.17 KFM69391.1 - 0.029 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Tissue factor HHH_9 PF17674.1 KFM69391.1 - 0.092 13.7 0.0 0.19 12.7 0.0 1.5 1 0 0 1 1 1 0 HHH domain PAP_assoc PF03828.19 KFM69393.1 - 4.7e-18 65.1 0.1 1.1e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF1830 PF08865.11 KFM69393.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Cu2_monooxygen PF01082.20 KFM69395.1 - 5.3e-30 104.3 0.0 6.4e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 KFM69396.1 - 1.8e-21 76.3 1.2 2e-21 76.1 1.2 1.0 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Hexokinase_2 PF03727.16 KFM69399.1 - 1.5e-89 299.6 0.0 1.9e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFM69399.1 - 1.8e-66 223.9 0.0 2.6e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase PTE PF02126.18 KFM69400.1 - 8.9e-63 212.5 0.0 9.8e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family TatD_DNase PF01026.21 KFM69400.1 - 0.00033 20.1 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Aminotran_1_2 PF00155.21 KFM69400.1 - 0.065 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF4276 PF14103.6 KFM69402.1 - 0.0023 18.2 0.5 0.0028 17.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4276) DUF1040 PF06288.13 KFM69402.1 - 0.031 14.7 1.7 0.043 14.2 1.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1040) Bcl-2 PF00452.19 KFM69403.1 - 0.00015 22.4 0.0 0.00027 21.6 0.0 1.5 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family EcoR124_C PF12008.8 KFM69403.1 - 0.028 14.1 0.3 0.034 13.8 0.3 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal OrfB_IS605 PF01385.19 KFM69403.1 - 0.041 14.1 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 Probable transposase NAD-GH PF10712.9 KFM69403.1 - 0.12 10.8 0.2 0.13 10.6 0.2 1.1 1 0 0 1 1 1 0 NAD-specific glutamate dehydrogenase BID PF06393.11 KFM69403.1 - 0.18 11.3 0.5 0.25 10.9 0.5 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) DDE_3 PF13358.6 KFM69404.1 - 3.1e-16 59.4 0.1 3e-15 56.3 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69404.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Sel1 PF08238.12 KFM69405.1 - 4.2e-18 65.4 4.5 6.5e-06 26.7 0.1 4.7 5 0 0 5 5 5 4 Sel1 repeat PHM7_cyt PF14703.6 KFM69405.1 - 0.11 12.7 2.4 0.62 10.3 0.4 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Fer4_21 PF14697.6 KFM69405.1 - 0.15 12.2 2.1 0.29 11.3 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain 7tm_1 PF00001.21 KFM69407.1 - 4.9e-34 117.8 2.0 6.1e-34 117.5 2.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM69407.1 - 8.8e-07 28.6 0.6 1.2e-06 28.2 0.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM69407.1 - 0.0014 18.3 0.6 0.0018 17.9 0.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Macoilin PF09726.9 KFM69408.1 - 5.2e-07 28.6 0.5 6.3e-07 28.4 0.5 1.1 1 0 0 1 1 1 1 Macoilin family Prenyltransf PF01255.19 KFM69409.1 - 1.4e-73 247.1 0.1 2.1e-73 246.6 0.1 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase MCR_alpha PF02249.17 KFM69409.1 - 0.087 13.3 0.8 12 6.3 0.0 3.0 3 0 0 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain R_equi_Vir PF05526.11 KFM69409.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein TFIIB PF00382.19 KFM69409.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat WD40 PF00400.32 KFM69410.1 - 9.8e-36 121.2 11.9 7e-06 26.7 0.0 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM69410.1 - 1.1e-07 32.0 0.1 0.13 12.5 0.2 5.8 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM69410.1 - 0.0016 17.4 0.1 0.51 9.2 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein HTH_Tnp_Tc3_2 PF01498.18 KFM69413.1 - 2.6e-07 30.8 0.4 4.4e-07 30.1 0.3 1.4 1 1 0 1 1 1 1 Transposase DEAD PF00270.29 KFM69414.1 - 4.7e-51 173.0 0.0 1.4e-50 171.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM69414.1 - 6.8e-31 106.9 0.0 1.6e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KFM69414.1 - 0.13 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Arf PF00025.21 KFM69416.1 - 2.4e-74 248.6 0.0 2.7e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFM69416.1 - 4.2e-15 56.0 0.0 6.1e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM69416.1 - 2.6e-14 53.2 0.0 3e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFM69416.1 - 5.4e-12 45.6 0.5 9.4e-08 31.6 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFM69416.1 - 1e-10 41.4 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFM69416.1 - 3.9e-10 39.5 0.0 4.8e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM69416.1 - 1.7e-05 24.8 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KFM69416.1 - 0.0019 18.8 0.0 0.0026 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KFM69416.1 - 0.0047 16.5 0.1 0.039 13.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFM69416.1 - 0.021 13.8 0.3 1.1 8.1 0.0 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 KFM69416.1 - 0.027 14.2 0.2 3.5 7.4 0.1 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KFM69416.1 - 0.031 13.9 0.2 6.9 6.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KFM69416.1 - 0.071 13.6 0.3 0.21 12.1 0.3 1.8 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 KFM69416.1 - 0.16 11.5 1.0 0.84 9.1 1.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B BTB PF00651.31 KFM69417.1 - 5.5e-29 100.6 5.5 1.5e-14 54.1 0.2 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ras PF00071.22 KFM69417.1 - 6.6e-29 100.6 0.0 1.8e-28 99.1 0.0 1.8 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM69417.1 - 1.1e-10 41.8 0.0 3.5e-10 40.1 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Lectin_leg-like PF03388.13 KFM69418.1 - 4.3e-95 317.5 0.1 5.2e-95 317.2 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFM69418.1 - 8.4e-13 48.8 0.2 1.1e-12 48.4 0.2 1.1 1 0 0 1 1 1 1 Bacterial lectin Laminin_G_2 PF02210.24 KFM69418.1 - 0.00011 22.7 0.1 0.0024 18.5 0.1 2.1 2 0 0 2 2 2 1 Laminin G domain Lectin_legB PF00139.19 KFM69418.1 - 0.00078 19.1 0.0 0.11 12.1 0.0 2.2 1 1 0 1 1 1 1 Legume lectin domain RhoGAP PF00620.27 KFM69419.1 - 5.7e-35 120.4 0.0 1.6e-34 118.9 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain RA PF00788.23 KFM69419.1 - 2.3e-08 34.6 0.0 7.3e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain IQ_SEC7_PH PF16453.5 KFM69419.1 - 0.0025 17.8 0.3 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 PH domain FERM_f0 PF16511.5 KFM69419.1 - 0.011 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 KFM69419.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 FERM N-terminal domain ADH_N PF08240.12 KFM69421.1 - 5e-27 93.9 1.8 7.3e-27 93.4 0.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM69421.1 - 2.1e-20 73.0 0.1 3.6e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2249 PF10006.9 KFM69421.1 - 0.0023 17.7 0.1 0.0098 15.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2249) Peptidase_M43 PF05572.13 KFM69421.1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Glu_dehyd_C PF16912.5 KFM69421.1 - 0.029 13.9 0.0 0.12 11.9 0.0 2.0 2 1 0 2 2 2 0 Glucose dehydrogenase C-terminus Met_10 PF02475.16 KFM69421.1 - 0.078 12.7 0.0 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Met-10+ like-protein Cytochrom_B561 PF03188.16 KFM69422.1 - 1.3e-39 135.5 9.1 1.3e-39 135.5 9.1 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4231 PF14015.6 KFM69422.1 - 0.01 16.3 2.8 0.16 12.5 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Ni_hydr_CYTB PF01292.20 KFM69422.1 - 0.039 13.6 13.2 0.014 15.0 4.6 2.6 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 PepSY_TM PF03929.16 KFM69422.1 - 0.046 13.4 0.5 0.046 13.4 0.5 3.1 2 2 1 3 3 3 0 PepSY-associated TM region CD47 PF04549.14 KFM69422.1 - 0.28 11.4 10.3 0.099 12.8 2.6 2.1 1 1 1 2 2 2 0 CD47 transmembrane region DUF2070 PF09843.9 KFM69422.1 - 3.8 5.7 8.3 4.7 5.4 8.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cpn60_TCP1 PF00118.24 KFM69423.1 - 5.4e-85 285.9 15.3 2.1e-84 283.9 15.3 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF126 PF01989.16 KFM69423.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Aconitase X swivel domain Phe_tRNA-synt_N PF02912.18 KFM69423.1 - 5.2 7.1 6.9 18 5.3 0.2 3.1 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Cpn10 PF00166.21 KFM69424.1 - 1.3e-30 105.3 0.0 1.4e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Peptidase_M22 PF00814.25 KFM69425.1 - 1.3e-41 143.2 0.0 1.5e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family HTH_Tnp_Tc3_2 PF01498.18 KFM69429.1 - 1e-15 57.7 6.5 1.7e-15 57.0 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69429.1 - 1.7e-15 57.1 0.1 2.9e-14 53.0 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM69429.1 - 0.00085 19.9 1.5 0.00085 19.9 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69429.1 - 0.0021 17.8 0.0 0.069 13.0 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69429.1 - 0.016 15.3 0.1 0.054 13.6 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69429.1 - 0.029 14.4 2.1 0.036 14.1 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM69429.1 - 0.032 14.1 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase ATP-synt_DE_N PF02823.16 KFM69430.1 - 2.5e-19 68.9 0.0 3.3e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DDE_3 PF13358.6 KFM69431.1 - 0.00011 22.0 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ham1p_like PF01725.16 KFM69432.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Ham1 family PI-PLC-Y PF00387.19 KFM69434.1 - 1.1e-29 103.1 0.8 1.1e-29 103.1 0.8 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KFM69434.1 - 2.4e-17 63.1 0.0 5.6e-17 61.9 0.0 1.6 1 1 0 1 1 1 1 C2 domain PI-PLC-X PF00388.19 KFM69435.1 - 1.6e-36 125.0 0.1 1.9e-36 124.8 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PH_12 PF16457.5 KFM69436.1 - 5.9e-15 56.0 0.3 1.7e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain EF-hand_7 PF13499.6 KFM69436.1 - 0.0029 18.0 0.4 0.015 15.8 0.2 2.4 2 1 0 2 2 2 1 EF-hand domain pair PH PF00169.29 KFM69436.1 - 0.022 15.3 0.0 0.056 14.0 0.0 1.7 1 0 0 1 1 1 0 PH domain EF-hand_6 PF13405.6 KFM69436.1 - 0.092 12.7 0.1 3.5 7.8 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Mcp5_PH PF12814.7 KFM69436.1 - 0.099 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_1 PF00036.32 KFM69436.1 - 0.11 12.0 0.0 6.1 6.6 0.0 2.6 2 0 0 2 2 2 0 EF hand EGF_CA PF07645.15 KFM69438.1 - 5.2e-10 39.4 17.9 2.1e-08 34.2 8.2 2.3 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF PF00008.27 KFM69438.1 - 3.5e-05 24.0 6.7 3.5e-05 24.0 6.7 2.3 2 0 0 2 2 2 1 EGF-like domain EGF_3 PF12947.7 KFM69438.1 - 6.3e-05 23.1 6.9 6.3e-05 23.1 6.9 2.3 2 0 0 2 2 2 1 EGF domain hEGF PF12661.7 KFM69438.1 - 0.00068 20.2 2.5 0.00068 20.2 2.5 3.2 3 0 0 3 3 3 1 Human growth factor-like EGF SEA PF01390.20 KFM69438.1 - 0.0046 17.0 0.6 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 SEA domain cEGF PF12662.7 KFM69438.1 - 0.14 12.1 8.3 0.13 12.2 0.6 2.6 2 0 0 2 2 2 0 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 KFM69438.1 - 1.1 9.6 5.0 2.8 8.3 5.0 1.6 1 0 0 1 1 1 0 Pvs28 EGF domain FXa_inhibition PF14670.6 KFM69438.1 - 1.9 8.9 16.1 0.23 11.8 5.4 2.4 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 KFM69438.1 - 2.3 8.4 11.6 0.57 10.3 3.8 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 EGF_2 PF07974.13 KFM69438.1 - 4.3 7.8 17.6 0.51 10.8 5.6 2.3 2 0 0 2 2 2 0 EGF-like domain TIL PF01826.17 KFM69438.1 - 8.4 6.7 13.0 1.5 9.1 2.4 2.3 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain DUF3730 PF12530.8 KFM69439.1 - 8.4e-14 51.7 0.7 8.4e-14 51.7 0.7 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3730) Focadhesin PF11229.8 KFM69440.1 - 1e-56 192.5 9.2 6.1e-49 166.8 0.9 2.2 1 1 1 2 2 2 2 Focadhesin JTB PF05439.12 KFM69441.1 - 5e-33 113.4 5.4 5e-33 113.4 5.4 1.5 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) DUF5083 PF16890.5 KFM69441.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5083) PIF1 PF05970.14 KFM69446.1 - 0.091 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase PI3_PI4_kinase PF00454.27 KFM69447.1 - 7.2e-36 124.3 0.1 3.5e-27 95.8 0.1 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFM69447.1 - 0.005 16.3 0.2 0.011 15.2 0.2 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KFM69447.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Tmemb_185A PF10269.9 KFM69449.1 - 1.4e-09 38.0 16.9 1.9e-08 34.3 16.1 1.9 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein CytochromB561_N PF09786.9 KFM69450.1 - 1.6e-83 281.7 1.0 2e-83 281.3 1.0 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal NPCC PF08058.11 KFM69450.1 - 0.011 15.7 1.2 0.039 14.0 0.0 2.5 2 0 0 2 2 2 0 Nuclear pore complex component EF-hand_7 PF13499.6 KFM69451.1 - 9.1e-18 64.5 2.8 1.9e-10 41.0 0.1 3.3 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM69451.1 - 3e-15 54.5 2.3 7.2e-06 25.2 0.2 5.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFM69451.1 - 2.6e-12 45.6 0.2 0.00049 19.8 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KFM69451.1 - 3.2e-09 35.9 0.1 0.00042 19.7 0.4 4.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KFM69451.1 - 7e-09 35.4 6.6 5.8e-05 22.8 1.4 4.4 4 1 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM69451.1 - 0.00026 21.3 0.1 0.00026 21.3 0.1 2.6 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFM69451.1 - 0.0014 18.4 2.6 0.072 13.0 0.1 2.7 2 0 0 2 2 2 1 EF hand CCD48 PF15799.5 KFM69451.1 - 0.012 14.0 0.1 0.26 9.6 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 48 EF-hand_4 PF12763.7 KFM69451.1 - 0.09 12.7 1.9 0.56 10.2 0.2 2.7 2 2 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Ashwin PF15323.6 KFM69451.1 - 0.67 9.9 7.0 1.3 9.0 7.0 1.5 1 0 0 1 1 1 0 Developmental protein XK-related PF09815.9 KFM69452.1 - 9.7e-87 291.2 26.7 1.2e-86 290.8 26.7 1.0 1 0 0 1 1 1 1 XK-related protein RUN PF02759.19 KFM69454.1 - 7.6e-07 29.2 0.0 8.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 RUN domain PH_RBD PF12068.8 KFM69455.1 - 1.5e-40 138.4 0.7 3.9e-40 137.1 0.0 1.9 2 0 0 2 2 2 1 Rab-binding domain (RBD) RabGAP-TBC PF00566.18 KFM69457.1 - 1.3e-09 38.0 1.5 1.3e-09 38.0 1.5 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ribosomal_S30 PF04758.14 KFM69458.1 - 0.16 12.2 0.3 0.3 11.3 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S30 PDZ PF00595.24 KFM69460.1 - 5.6e-08 33.0 0.2 3.6e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 PDZ domain DUF2681 PF10883.8 KFM69460.1 - 0.011 16.1 0.4 0.011 16.1 0.4 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2681) PDZ_2 PF13180.6 KFM69460.1 - 0.017 15.4 2.3 0.06 13.7 0.0 3.0 3 0 0 3 3 3 0 PDZ domain PDZ_6 PF17820.1 KFM69460.1 - 0.1 12.4 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 PDZ domain Phage_holin_2_4 PF16082.5 KFM69460.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like QVR PF17064.5 KFM69462.1 - 0.0058 16.8 9.7 0.011 16.0 9.7 1.5 1 1 0 1 1 1 1 Sleepless protein DUF753 PF05444.12 KFM69462.1 - 0.29 11.1 11.4 1 9.3 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF753) HTH_Tnp_Tc3_2 PF01498.18 KFM69463.1 - 5.1e-16 58.7 3.5 6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69463.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69463.1 - 1.1e-07 31.5 2.0 7.3e-07 28.8 0.2 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69463.1 - 0.0027 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69463.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Chitin_bind_4 PF00379.23 KFM69465.1 - 3.4e-07 30.7 1.4 3.4e-07 30.7 1.4 2.2 2 0 0 2 2 2 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM69467.1 - 1.5e-07 31.8 5.2 1.5e-07 31.8 5.2 1.6 2 0 0 2 2 2 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM69468.1 - 5.7e-06 26.8 4.9 1e-05 26.0 4.9 1.5 1 0 0 1 1 1 1 Insect cuticle protein HTH_23 PF13384.6 KFM69469.1 - 2.4e-10 39.9 0.8 4.4e-10 39.1 0.1 1.9 2 0 0 2 2 1 1 Homeodomain-like domain HTH_29 PF13551.6 KFM69469.1 - 4.8e-09 36.1 0.5 1.7e-08 34.3 0.4 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM69469.1 - 6.8e-09 35.7 0.9 1.8e-08 34.4 0.3 2.1 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KFM69469.1 - 2.3e-06 27.3 0.1 5.1e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Terminase_5 PF06056.12 KFM69469.1 - 0.00017 21.4 0.1 0.00035 20.4 0.1 1.5 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_Crp_2 PF13545.6 KFM69469.1 - 0.00074 19.4 1.8 0.004 17.1 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_7 PF02796.15 KFM69469.1 - 0.0014 18.6 0.0 0.0038 17.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 KFM69469.1 - 0.003 17.5 0.1 0.82 9.7 0.0 2.4 2 0 0 2 2 2 1 HTH domain HTH_30 PF13556.6 KFM69469.1 - 0.0089 15.8 0.2 0.19 11.6 0.0 2.3 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_IclR PF09339.10 KFM69469.1 - 0.012 15.4 0.1 0.066 13.0 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_AraC PF00165.23 KFM69469.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Sigma70_r4_2 PF08281.12 KFM69469.1 - 0.035 13.8 0.2 0.097 12.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 DDE_3 PF13358.6 KFM69469.1 - 0.049 13.4 0.7 0.07 12.9 0.0 1.7 2 0 0 2 2 1 0 DDE superfamily endonuclease HTH_40 PF14493.6 KFM69469.1 - 0.16 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KFM69469.1 - 0.18 11.6 1.2 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_36 PF13730.6 KFM69469.1 - 0.22 11.5 0.7 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Crp PF00325.20 KFM69469.1 - 0.52 10.0 1.7 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family HTH_32 PF13565.6 KFM69469.1 - 6.9 7.4 9.4 0.38 11.4 0.4 3.1 3 1 0 3 3 3 0 Homeodomain-like domain zf-DNA_Pol PF08996.10 KFM69470.1 - 4e-42 144.0 8.7 4.9e-42 143.8 8.7 1.1 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger MCM PF00493.23 KFM69470.1 - 0.057 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Alpha-amylase_N PF02903.14 KFM69470.1 - 0.26 11.5 1.2 0.63 10.2 0.3 1.9 2 0 0 2 2 2 0 Alpha amylase, N-terminal ig-like domain DNA_pol_B PF00136.21 KFM69471.1 - 1.2e-41 142.9 0.3 1.3e-41 142.8 0.3 1.0 1 0 0 1 1 1 1 DNA polymerase family B DUF4940 PF16298.5 KFM69471.1 - 0.073 12.7 0.4 0.41 10.3 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4940) DNA_pol_B PF00136.21 KFM69472.1 - 6e-63 213.1 0.0 7.6e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFM69472.1 - 6.7e-24 84.7 0.0 3.9e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 KFM69472.1 - 0.00052 19.0 0.1 0.00099 18.1 0.1 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KFM69472.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB INCENP_N PF12178.8 KFM69473.1 - 0.027 14.5 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal DNA_pol_alpha_N PF12254.8 KFM69474.1 - 1.4e-18 66.7 2.1 1.4e-18 66.7 2.1 2.8 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal TPR_8 PF13181.6 KFM69476.1 - 7.3e-13 47.6 4.0 3.4e-05 23.7 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM69476.1 - 1.1e-12 47.1 4.5 0.00043 20.2 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM69476.1 - 1.1e-12 47.1 2.2 1.9e-05 24.3 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM69476.1 - 6.2e-11 41.8 1.4 6.5e-07 28.9 1.1 3.3 3 1 1 4 4 4 2 TPR repeat TPR_17 PF13431.6 KFM69476.1 - 7.1e-09 35.4 0.9 0.0041 17.4 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM69476.1 - 8.5e-07 29.2 3.0 0.002 18.4 0.1 4.6 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM69476.1 - 4.1e-06 27.3 1.7 0.0041 17.7 0.5 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM69476.1 - 1.4e-05 25.5 6.2 0.0011 19.4 0.3 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM69476.1 - 2.4e-05 24.8 5.5 0.14 13.1 0.1 5.6 4 2 3 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM69476.1 - 6e-05 22.4 6.2 0.17 11.0 0.8 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM69476.1 - 6.4e-05 22.7 6.0 3.6 7.8 0.1 4.7 3 2 2 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM69476.1 - 0.0087 16.3 1.4 0.0087 16.3 1.4 3.9 2 2 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFM69476.1 - 0.0099 15.7 4.6 19 5.3 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 KFM69476.1 - 0.28 11.5 3.8 0.6 10.4 0.6 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein zf-H2C2_2 PF13465.6 KFM69477.1 - 9.2e-92 297.7 104.9 5.2e-08 33.0 0.6 16.2 16 0 0 16 16 16 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69477.1 - 6.1e-57 187.0 141.6 4e-06 27.0 0.5 15.3 17 0 0 17 17 15 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69477.1 - 1.6e-50 165.4 122.7 0.00011 22.8 2.2 15.5 15 0 0 15 15 15 13 C2H2-type zinc finger zf-met PF12874.7 KFM69477.1 - 3.8e-43 144.7 111.4 0.00056 20.2 1.3 14.5 14 0 0 14 14 14 13 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM69477.1 - 9.2e-21 73.4 106.2 0.0024 17.8 1.3 14.6 15 0 0 15 15 15 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM69477.1 - 7.1e-17 61.2 93.7 0.021 15.1 0.7 14.5 13 2 1 14 14 13 11 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM69477.1 - 1.7e-06 28.2 16.7 3.7 7.9 0.1 8.5 1 1 6 8 8 8 3 BolA-like protein GAGA PF09237.11 KFM69477.1 - 4.8e-05 23.1 19.7 8.6 6.2 0.2 9.8 3 2 8 11 11 11 1 GAGA factor zf-C2H2_9 PF16293.5 KFM69477.1 - 0.00032 20.5 54.3 2 8.3 0.1 13.0 8 3 7 15 15 15 4 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM69477.1 - 0.0016 18.5 65.4 1 9.5 0.8 13.0 14 0 0 14 14 14 5 DBF zinc finger zf-C2H2_11 PF16622.5 KFM69477.1 - 0.013 15.2 73.8 0.074 12.8 0.3 11.9 12 0 0 12 12 11 0 zinc-finger C2H2-type YqzL PF14006.6 KFM69477.1 - 0.2 12.1 0.0 31 5.0 0.0 3.4 3 0 0 3 3 3 0 YqzL-like protein Thioredoxin_16 PF18569.1 KFM69477.1 - 0.89 9.7 11.2 2.7 8.2 0.0 4.5 4 2 1 5 5 5 0 Thioredoxin-like domain zf-C2HC_2 PF13913.6 KFM69477.1 - 2.2 8.3 65.1 5.2 7.1 0.2 12.7 13 0 0 13 13 13 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM69477.1 - 9.7 5.9 59.0 2 8.1 2.0 11.6 8 5 5 13 13 13 0 MYST family zinc finger domain TPR_20 PF14561.6 KFM69480.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_5 PF12688.7 KFM69480.1 - 0.12 12.7 0.8 0.36 11.1 0.4 1.9 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_4 PF07721.14 KFM69480.1 - 0.46 11.2 4.3 4.4 8.2 0.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.16 KFM69482.1 - 3.8e-15 55.7 0.0 6.9e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Kdo PF06293.14 KFM69483.1 - 3.3e-09 36.4 0.0 4.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFM69483.1 - 3.3e-08 33.2 0.0 3.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM69483.1 - 3.5e-07 29.8 0.0 4.2e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFM69483.1 - 7e-06 25.8 0.1 3.4e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFM69483.1 - 0.00064 19.7 0.0 0.0018 18.3 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFM69483.1 - 0.021 14.1 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Kinase-like PF14531.6 KFM69483.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DAGK_cat PF00781.24 KFM69484.1 - 5.1e-25 87.5 0.4 7.8e-25 86.9 0.4 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 KFM69484.1 - 6.2e-05 22.0 0.0 0.0001 21.2 0.0 1.4 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Peptidase_S51 PF03575.17 KFM69484.1 - 0.0066 16.1 0.1 0.017 14.8 0.1 1.6 1 1 0 1 1 1 1 Peptidase family S51 Tnp_P_element_C PF12596.8 KFM69485.1 - 5.1e-08 33.4 0.0 9.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 87kDa Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM69486.1 - 4.5e-16 58.8 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69486.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69486.1 - 2e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69486.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69486.1 - 7.7 7.2 18.3 0.12 13.0 1.9 3.5 3 1 1 4 4 4 0 Homeodomain-like domain UPF0016 PF01169.19 KFM69487.1 - 1.2e-08 35.1 0.1 2.1e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized protein family UPF0016 Apolipoprotein PF01442.18 KFM69487.1 - 4.4e-07 30.0 11.1 7.5e-05 22.7 1.4 2.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Phasin PF05597.11 KFM69487.1 - 5.9e-07 29.5 20.4 1.7e-06 28.1 6.3 2.3 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 KFM69487.1 - 0.00027 21.0 19.7 0.0019 18.2 7.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Prominin PF05478.11 KFM69487.1 - 0.00028 19.0 5.7 0.00039 18.5 5.7 1.2 1 0 0 1 1 1 1 Prominin Spc7 PF08317.11 KFM69487.1 - 0.00035 19.6 16.7 0.00052 19.0 16.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KFM69487.1 - 0.00056 20.0 0.2 0.092 12.8 0.1 2.6 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 KFM69487.1 - 0.0007 19.6 5.1 0.45 10.5 0.3 3.0 1 1 2 3 3 2 2 Apolipoprotein O DUF3584 PF12128.8 KFM69487.1 - 0.0016 16.1 9.3 0.0019 15.8 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CdvA PF18822.1 KFM69487.1 - 0.0026 17.6 19.9 0.48 10.3 2.2 3.3 2 1 1 3 3 3 2 CdvA-like coiled-coil domain Tweety PF04906.13 KFM69487.1 - 0.003 16.3 1.4 0.003 16.3 1.4 1.8 1 1 1 2 2 2 1 Tweety DUF1640 PF07798.11 KFM69487.1 - 0.0031 17.6 16.4 0.0078 16.3 12.7 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1640) SNARE PF05739.19 KFM69487.1 - 0.0049 16.8 2.1 0.95 9.5 0.1 2.9 2 1 0 2 2 2 1 SNARE domain NPV_P10 PF05531.12 KFM69487.1 - 0.007 16.8 10.8 0.38 11.3 1.6 3.6 1 1 3 4 4 4 1 Nucleopolyhedrovirus P10 protein DUF5446 PF17522.2 KFM69487.1 - 0.0074 16.4 0.4 0.0074 16.4 0.4 3.7 1 1 3 4 4 3 1 Family of unknown function (DUF5446) ApoLp-III PF07464.11 KFM69487.1 - 0.012 15.7 19.2 0.045 13.8 19.3 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) AAA_13 PF13166.6 KFM69487.1 - 0.013 14.2 9.3 0.017 13.8 9.3 1.2 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.11 KFM69487.1 - 0.015 15.7 5.6 0.015 15.7 5.6 4.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) HSBP1 PF06825.12 KFM69487.1 - 0.017 15.0 0.5 0.71 9.8 0.1 3.2 2 1 1 3 3 3 0 Heat shock factor binding protein 1 DUF4407 PF14362.6 KFM69487.1 - 0.022 14.1 11.4 0.1 12.0 11.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PMEI PF04043.15 KFM69487.1 - 0.023 15.0 3.8 0.13 12.6 3.8 1.9 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Exonuc_VII_L PF02601.15 KFM69487.1 - 0.031 13.8 3.1 0.051 13.1 3.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.7 KFM69487.1 - 0.034 14.3 21.3 0.05 13.8 19.3 1.9 1 1 1 2 2 2 0 Tropomyosin like ABC_tran_CTD PF16326.5 KFM69487.1 - 0.041 14.1 12.5 0.051 13.8 0.8 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain SF-assemblin PF06705.11 KFM69487.1 - 0.041 13.2 20.4 0.32 10.3 12.7 2.2 1 1 1 2 2 2 0 SF-assemblin/beta giardin HrpB7 PF09486.10 KFM69487.1 - 0.041 14.3 10.9 0.12 12.8 10.7 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Dynamitin PF04912.14 KFM69487.1 - 0.051 12.9 16.8 0.064 12.6 5.0 2.4 1 1 1 2 2 2 0 Dynamitin AAA_32 PF13654.6 KFM69487.1 - 0.076 11.8 11.3 0.11 11.2 11.3 1.2 1 0 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 KFM69487.1 - 0.099 12.1 18.5 0.21 11.0 18.5 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 CHASE3 PF05227.13 KFM69487.1 - 0.1 12.5 3.7 0.24 11.3 1.7 2.2 1 1 1 2 2 2 0 CHASE3 domain GP41 PF00517.17 KFM69487.1 - 0.11 12.4 5.8 2.5 8.0 0.7 2.5 1 1 1 2 2 2 0 Retroviral envelope protein FlgN PF05130.12 KFM69487.1 - 0.11 13.0 2.8 0.28 11.7 0.5 2.4 1 1 1 2 2 2 0 FlgN protein FlxA PF14282.6 KFM69487.1 - 0.12 12.3 12.3 0.45 10.5 1.4 2.4 1 1 1 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 KFM69487.1 - 0.13 12.5 13.3 0.055 13.7 3.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 KFM69487.1 - 0.16 11.7 6.8 0.24 11.1 0.9 2.6 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain UPF0184 PF03670.13 KFM69487.1 - 0.19 12.1 1.5 0.85 10.1 0.8 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DHR10 PF18595.1 KFM69487.1 - 0.19 11.8 17.5 0.08 13.0 14.2 2.1 2 0 0 2 2 1 0 Designed helical repeat protein 10 domain Spectrin PF00435.21 KFM69487.1 - 0.2 12.2 12.2 1.6 9.3 9.5 2.9 1 1 1 2 2 2 0 Spectrin repeat DUF725 PF05267.12 KFM69487.1 - 0.21 11.6 6.8 2.2 8.3 0.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF725) HalX PF08663.10 KFM69487.1 - 0.26 11.6 2.5 29 5.1 0.1 3.5 1 1 2 3 3 3 0 HalX domain COG2 PF06148.11 KFM69487.1 - 0.27 11.3 19.1 0.55 10.3 6.9 3.3 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.13 KFM69487.1 - 0.29 11.7 10.2 3.7 8.2 2.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Uso1_p115_C PF04871.13 KFM69487.1 - 0.3 11.5 18.5 0.7 10.3 1.4 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4795 PF16043.5 KFM69487.1 - 0.34 10.5 17.0 3.2 7.3 17.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) CLZ PF16526.5 KFM69487.1 - 0.34 11.3 10.0 0.25 11.7 0.6 3.2 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4988 PF16378.5 KFM69487.1 - 0.37 10.4 6.2 0.96 9.1 0.7 3.1 1 1 2 3 3 3 0 Domain of unknown function Snapin_Pallidin PF14712.6 KFM69487.1 - 0.41 11.1 12.0 0.4 11.1 1.7 3.2 1 1 2 3 3 3 0 Snapin/Pallidin SKA2 PF16740.5 KFM69487.1 - 0.42 10.4 13.1 0.31 10.8 0.5 3.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4709 PF15821.5 KFM69487.1 - 0.48 10.7 9.5 0.28 11.5 4.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) MIS13 PF08202.11 KFM69487.1 - 0.48 9.7 10.3 1.5 8.0 10.3 1.7 1 1 0 1 1 1 0 Mis12-Mtw1 protein family DUF148 PF02520.17 KFM69487.1 - 0.48 10.5 15.7 4.6 7.4 8.7 3.2 1 1 2 3 3 3 0 Domain of unknown function DUF148 Occludin_ELL PF07303.13 KFM69487.1 - 0.59 10.9 9.6 0.63 10.8 5.7 2.6 1 1 2 3 3 3 0 Occludin homology domain Prefoldin_2 PF01920.20 KFM69487.1 - 0.63 10.0 21.0 0.088 12.8 2.0 3.3 1 1 2 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.9 KFM69487.1 - 1 9.7 13.8 0.5 10.7 4.1 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glycoprot_B_PH2 PF17417.2 KFM69487.1 - 1 9.7 6.0 4.5 7.7 1.1 3.2 1 1 2 3 3 3 0 Herpesvirus Glycoprotein B PH-like domain DUF2433 PF10360.9 KFM69487.1 - 1.4 9.1 4.7 5.8 7.0 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) Peptidase_S64 PF08192.11 KFM69487.1 - 1.5 7.2 11.8 3.3 6.1 11.7 1.4 1 1 0 1 1 1 0 Peptidase family S64 FliT PF05400.13 KFM69487.1 - 1.5 9.7 4.5 8.3 7.3 0.4 2.9 1 1 1 2 2 2 0 Flagellar protein FliT YkyA PF10368.9 KFM69487.1 - 1.6 8.3 21.9 0.48 10.1 18.8 1.6 2 0 0 2 2 1 0 Putative cell-wall binding lipoprotein TPR_MLP1_2 PF07926.12 KFM69487.1 - 1.7 8.7 19.2 0.62 10.1 15.4 2.1 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein Mod_r PF07200.13 KFM69487.1 - 2.3 8.3 9.8 6.1 6.9 1.3 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Syntaxin-6_N PF09177.11 KFM69487.1 - 2.5 8.7 12.8 2.1 9.0 4.9 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.13 KFM69487.1 - 2.5 7.6 13.9 3 7.4 3.1 3.0 1 1 2 3 3 3 0 fzo-like conserved region PIN_8 PF18476.1 KFM69487.1 - 2.8 7.7 13.2 25 4.6 13.2 2.1 1 1 0 1 1 1 0 PIN like domain HIP1_clath_bdg PF16515.5 KFM69487.1 - 2.8 8.6 17.9 8.8 7.0 2.8 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2400 PF09674.10 KFM69487.1 - 2.9 7.8 6.1 15 5.5 6.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) Med9 PF07544.13 KFM69487.1 - 2.9 8.0 9.0 4 7.6 2.5 2.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.11 KFM69487.1 - 3.2 8.1 10.5 25 5.2 5.5 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CCDC53 PF10152.9 KFM69487.1 - 3.4 8.1 10.6 0.11 12.9 2.5 2.1 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex DUF16 PF01519.16 KFM69487.1 - 3.9 8.0 21.8 4.5 7.8 6.3 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 ATG16 PF08614.11 KFM69487.1 - 4 7.6 12.2 5.8 7.1 9.7 2.2 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KFM69487.1 - 4.4 7.7 17.8 9.1 6.7 17.8 1.5 1 1 0 1 1 1 0 Fez1 MtrG PF04210.13 KFM69487.1 - 5 7.1 8.6 2.9 7.8 0.4 3.6 2 1 2 4 4 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G ADIP PF11559.8 KFM69487.1 - 5 7.2 11.9 10 6.2 2.9 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FAP206 PF12018.8 KFM69487.1 - 5.3 6.5 9.5 5.3 6.5 6.9 2.2 1 1 1 2 2 2 0 Domain of unknown function DASH_Duo1 PF08651.10 KFM69487.1 - 5.9 6.7 7.4 40 4.1 0.2 3.9 2 1 1 4 4 3 0 DASH complex subunit Duo1 DUF5082 PF16888.5 KFM69487.1 - 6.4 7.1 16.0 18 5.6 12.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Seryl_tRNA_N PF02403.22 KFM69487.1 - 6.5 7.0 23.1 1.1 9.5 8.1 3.1 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FH2 PF02181.23 KFM69487.1 - 6.6 5.7 14.2 68 2.4 14.2 2.2 1 1 0 1 1 1 0 Formin Homology 2 Domain WASH_WAHD PF11945.8 KFM69487.1 - 6.7 6.1 15.1 6.6 6.2 1.9 3.1 1 1 2 3 3 3 0 WAHD domain of WASH complex TMPIT PF07851.13 KFM69487.1 - 8 5.6 16.4 1.6 7.9 6.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF4404 PF14357.6 KFM69487.1 - 8.1 7.2 9.0 3.9 8.2 0.2 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4404) Atg14 PF10186.9 KFM69487.1 - 9.2 5.2 12.1 15 4.5 12.1 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 gag-asp_proteas PF13975.6 KFM69488.1 - 1.1e-11 45.1 0.0 2.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM69488.1 - 8.6e-10 39.1 0.0 1.9e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 KFM69488.1 - 1.3e-09 37.6 9.2 0.00024 21.0 1.8 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFM69488.1 - 5.3e-09 35.8 9.1 0.00035 20.3 2.2 2.5 2 0 0 2 2 2 2 Zinc knuckle Asp_protease PF09668.10 KFM69488.1 - 0.00028 20.7 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_4 PF14392.6 KFM69488.1 - 0.0077 15.9 5.3 0.99 9.2 0.5 2.7 2 0 0 2 2 2 2 Zinc knuckle RVP PF00077.20 KFM69488.1 - 0.014 15.7 0.0 0.053 13.8 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF4407 PF14362.6 KFM69488.1 - 0.035 13.5 1.6 0.065 12.6 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2_10 PF16588.5 KFM69488.1 - 0.051 13.3 9.2 1.6 8.6 1.0 2.6 2 0 0 2 2 2 0 C2H2 zinc-finger HSBP1 PF06825.12 KFM69488.1 - 0.14 12.1 0.1 0.44 10.4 0.1 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 V_ATPase_I PF01496.19 KFM69488.1 - 0.23 9.3 0.1 0.37 8.6 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HscB_4_cys PF18256.1 KFM69488.1 - 0.3 10.9 12.1 0.28 11.0 3.2 2.7 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif PrgH PF09480.10 KFM69489.1 - 0.098 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) CNRIP1 PF15043.6 KFM69490.1 - 1.1e-40 138.7 0.3 1.3e-40 138.6 0.3 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 zf-RING_UBOX PF13445.6 KFM69491.1 - 5.9e-08 32.6 9.6 1.5e-07 31.3 9.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM69491.1 - 1.3e-07 31.4 9.3 2.6e-07 30.5 9.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFM69491.1 - 8.2e-07 29.3 8.5 1.6e-06 28.4 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM69491.1 - 1.3e-06 28.2 6.7 2.4e-06 27.3 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFM69491.1 - 1.2e-05 25.3 8.9 3.1e-05 24.0 8.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFM69491.1 - 2.3e-05 24.1 8.8 5.4e-05 23.0 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM69491.1 - 3.1e-05 23.7 8.5 0.0004 20.2 3.2 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 FYVE PF01363.21 KFM69491.1 - 7e-05 22.9 0.2 0.0001 22.4 0.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 KFM69491.1 - 0.00037 20.3 8.7 0.00086 19.1 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFM69491.1 - 0.12 12.2 4.6 0.83 9.6 4.6 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 KFM69491.1 - 0.28 11.1 6.4 0.8 9.6 6.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Elf1 PF05129.13 KFM69491.1 - 0.42 10.7 3.3 0.96 9.5 3.3 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-RING_11 PF17123.5 KFM69491.1 - 1 9.1 6.9 0.38 10.6 1.1 2.5 2 0 0 2 2 2 0 RING-like zinc finger DUF4428 PF14471.6 KFM69491.1 - 1.2 9.2 6.6 1.5 8.8 4.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) ROQ_II PF18386.1 KFM69492.1 - 1.1e-31 108.4 0.1 2e-31 107.6 0.1 1.4 1 0 0 1 1 1 1 Roquin II domain zf-CCCH PF00642.24 KFM69492.1 - 4.4e-07 29.6 1.3 9.6e-07 28.6 1.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM69492.1 - 0.00026 20.9 0.5 0.00078 19.4 0.5 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFM69492.1 - 0.0093 15.8 0.4 0.019 14.7 0.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Wax2_C PF12076.8 KFM69492.1 - 0.021 14.6 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 WAX2 C-terminal domain DUF4928 PF16280.5 KFM69493.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) AIP3 PF03915.13 KFM69496.1 - 5.1e-23 81.8 14.5 2.6e-12 46.6 0.2 2.7 3 0 0 3 3 3 2 Actin interacting protein 3 LssY_C PF14067.6 KFM69496.1 - 0.022 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 LssY C-terminus Prominin PF05478.11 KFM69496.1 - 5.6 4.8 5.8 8.8 4.1 5.8 1.2 1 0 0 1 1 1 0 Prominin HECT PF00632.25 KFM69497.1 - 1.3e-26 93.8 0.1 1.4e-26 93.7 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 KFM69498.1 - 1.9e-10 41.4 0.6 5.9e-07 30.2 0.0 3.4 3 2 0 3 3 3 2 Filamin/ABP280 repeat Bac_A_amyl_C PF18612.1 KFM69499.1 - 0.09 12.6 0.0 0.33 10.8 0.0 1.9 1 1 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain RE_R_Pab1 PF09522.10 KFM69500.1 - 0.01 15.9 0.2 0.017 15.2 0.2 1.3 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease TTL PF03133.15 KFM69501.1 - 1.4e-26 93.4 0.2 1.6e-26 93.1 0.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFM69501.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KFM69501.1 - 0.03 13.9 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 KFM69501.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF778 PF05608.12 KFM69502.1 - 4.7e-43 147.8 5.2 1.1e-22 81.4 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Auto_anti-p27 PF06677.12 KFM69502.1 - 1.6 8.9 6.8 0.82 9.9 0.3 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PKD PF00801.20 KFM69503.1 - 0.025 14.4 0.2 1 9.3 0.1 2.6 2 1 0 2 2 2 0 PKD domain Crystall_2 PF09076.10 KFM69503.1 - 0.19 11.6 1.3 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 Beta/Gamma crystallin TNFR_16_TM PF18422.1 KFM69503.1 - 0.25 11.3 3.2 0.63 10.0 3.2 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain RasGAP_C PF03836.15 KFM69504.1 - 2.6e-28 98.9 12.7 3.4e-28 98.5 12.7 1.2 1 0 0 1 1 1 1 RasGAP C-terminus LMP PF04778.12 KFM69504.1 - 0.019 14.9 5.4 0.03 14.2 5.4 1.3 1 0 0 1 1 1 0 LMP repeated region COG5 PF10392.9 KFM69504.1 - 0.092 12.9 2.2 0.17 12.1 2.2 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Histone PF00125.24 KFM69505.1 - 1.9e-19 70.4 0.0 2.3e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFM69505.1 - 3.7e-13 49.0 0.6 7.6e-13 48.0 0.6 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFM69505.1 - 0.0046 17.2 0.0 0.0075 16.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.25 KFM69506.1 - 9.8e-35 120.2 0.2 1.3e-34 119.7 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM69506.1 - 3.6e-15 55.9 0.1 5.3e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CortBP2 PF09727.9 KFM69507.1 - 0.0089 16.0 0.8 0.0089 16.0 0.8 1.0 1 0 0 1 1 1 1 Cortactin-binding protein-2 MRVI1 PF05781.12 KFM69508.1 - 1.6e-45 155.9 14.0 2.3e-45 155.3 14.0 1.2 1 0 0 1 1 1 1 MRVI1 protein CS PF04969.16 KFM69509.1 - 7.2e-13 49.4 0.2 1.1e-12 48.8 0.2 1.3 1 0 0 1 1 1 1 CS domain HTH_Tnp_Tc3_2 PF01498.18 KFM69510.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69510.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease LETM1 PF07766.13 KFM69511.1 - 1.1e-106 356.1 7.6 1.1e-106 356.1 7.6 3.4 2 1 0 3 3 3 1 LETM1-like protein SAP PF02037.27 KFM69511.1 - 0.0087 15.8 3.4 0.082 12.7 0.0 3.6 3 0 0 3 3 3 1 SAP domain UCH PF00443.29 KFM69511.1 - 0.041 13.4 0.2 3.3 7.1 0.0 3.1 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase EF-hand_6 PF13405.6 KFM69511.1 - 0.064 13.2 0.1 24 5.2 0.0 4.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 KFM69511.1 - 1.3 9.5 7.8 0.27 11.7 0.4 3.5 3 1 1 4 4 4 0 EF-hand domain pair DUF2746 PF10874.8 KFM69511.1 - 7 7.1 7.2 1.1 9.8 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2746) Sod_Cu PF00080.20 KFM69512.1 - 1.8e-19 70.3 0.0 4.9e-06 26.8 0.0 3.9 3 1 0 3 3 3 3 Copper/zinc superoxide dismutase (SODC) Adipokin_hormo PF06377.11 KFM69513.1 - 0.035 14.5 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 Adipokinetic hormone Corazonin PF17308.2 KFM69514.1 - 6.4e-07 29.8 0.4 8.4e-07 29.4 0.4 1.2 1 0 0 1 1 1 1 Pro-corazonin Gastrin PF00918.17 KFM69514.1 - 0.087 13.8 0.1 0.1 13.5 0.1 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family 7tm_1 PF00001.21 KFM69515.1 - 1.7e-78 263.6 4.7 2.3e-78 263.2 4.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFM69515.1 - 9.7e-08 32.1 0.7 9.7e-08 32.1 0.7 1.9 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFM69515.1 - 8.1e-06 25.4 10.1 0.00048 19.6 5.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM69515.1 - 0.0004 20.1 10.4 0.0004 20.1 10.4 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx HTH_Tnp_Tc3_2 PF01498.18 KFM69516.1 - 2.4e-16 59.8 2.2 4.8e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69516.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ACAS_N PF16177.5 KFM69516.1 - 0.21 11.6 1.9 7.4 6.6 0.8 2.4 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus P16-Arc PF04699.14 KFM69517.1 - 0.11 12.9 0.1 1.4 9.4 0.1 2.2 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) CCDC142 PF14923.6 KFM69518.1 - 8.5e-10 38.0 1.5 1.3e-09 37.4 1.5 1.2 1 0 0 1 1 1 1 Coiled-coil protein 142 EF-hand_7 PF13499.6 KFM69519.1 - 2e-24 85.8 0.4 1.8e-18 66.7 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM69519.1 - 1.9e-21 74.0 0.8 2.3e-07 29.9 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFM69519.1 - 6.4e-19 66.2 1.1 0.00011 21.8 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFM69519.1 - 5e-15 54.2 1.7 3.5e-06 26.3 0.2 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFM69519.1 - 1.7e-12 47.0 3.8 0.00015 21.5 0.6 3.2 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM69519.1 - 1.5e-05 25.3 0.1 0.0034 17.7 0.1 2.8 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFM69519.1 - 0.0016 18.3 0.7 2.4 8.1 0.0 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFM69519.1 - 0.0048 17.1 0.9 0.067 13.4 0.4 2.6 2 1 0 2 2 2 1 Dockerin type I domain EF-hand_9 PF14658.6 KFM69519.1 - 0.023 15.0 0.1 4.1 7.8 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain p25-alpha PF05517.12 KFM69519.1 - 0.12 12.6 0.1 6.1 7.0 0.1 2.2 1 1 1 2 2 2 0 p25-alpha FG-GAP PF01839.23 KFM69519.1 - 0.12 12.5 2.4 0.76 10.0 0.1 2.8 3 0 0 3 3 3 0 FG-GAP repeat Ku_PK_bind PF08785.11 KFM69519.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Ku C terminal domain like EF-hand_3 PF09069.11 KFM69519.1 - 0.18 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand Caleosin PF05042.13 KFM69519.1 - 1.2 9.1 5.0 9.9 6.1 0.4 3.2 3 1 1 4 4 4 0 Caleosin related protein RVP PF00077.20 KFM69520.1 - 0.00016 21.9 0.1 0.00037 20.8 0.1 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KFM69520.1 - 0.0018 18.8 0.0 0.0027 18.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KFM69520.1 - 0.0036 17.1 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 KFM69520.1 - 0.017 15.7 0.1 0.048 14.3 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease zf-MYND PF01753.18 KFM69521.1 - 2.2e-06 27.6 8.2 2.2e-06 27.6 8.2 2.4 2 0 0 2 2 2 1 MYND finger Glyco_hydro_31 PF01055.26 KFM69525.1 - 3.4e-12 46.3 0.0 5.1e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 KFM69525.1 - 0.031 14.5 0.1 0.089 13.1 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5110) SNRNP27 PF08648.12 KFM69527.1 - 0.0067 16.5 0.0 0.0072 16.4 0.0 1.0 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DIX PF00778.17 KFM69529.1 - 2.3e-29 101.0 0.0 4e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 DIX domain RabGAP-TBC PF00566.18 KFM69530.1 - 8.1e-18 64.9 1.9 1.9e-17 63.6 2.1 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 KFM69530.1 - 6.4e-06 26.6 0.5 2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Carboxyl_trans PF01039.22 KFM69531.1 - 3.6e-07 29.2 0.0 3.7e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain VHS PF00790.19 KFM69532.1 - 4.3e-30 104.4 1.0 9.7e-30 103.3 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KFM69532.1 - 2.6e-26 92.1 0.1 6.9e-26 90.7 0.1 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 KFM69532.1 - 6.4e-20 70.5 5.0 6.4e-20 70.5 5.0 2.1 2 0 0 2 2 2 1 GGA N-GAT domain GAT PF03127.14 KFM69532.1 - 6.4e-18 64.8 3.6 9.5e-18 64.3 0.3 3.0 3 0 0 3 3 3 1 GAT domain Complex1_LYR_2 PF13233.6 KFM69532.1 - 0.48 11.2 1.7 1.3 9.8 1.7 1.7 1 0 0 1 1 1 0 Complex1_LYR-like DUF719 PF05334.13 KFM69532.1 - 3.6 7.8 11.9 0.55 10.4 5.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF719) Josephin PF02099.17 KFM69533.1 - 2.2e-25 89.6 1.5 9.1e-24 84.4 1.5 2.4 1 1 0 1 1 1 1 Josephin Peptidase_C12 PF01088.21 KFM69533.1 - 0.005 16.6 0.3 0.086 12.6 0.3 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ac81 PF05820.11 KFM69533.1 - 0.044 13.3 4.3 0.069 12.7 4.0 1.5 1 1 0 1 1 1 0 Baculoviridae AC81 DUF4860 PF16152.5 KFM69533.1 - 0.059 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4860) PX PF00787.24 KFM69534.1 - 1.7e-17 63.4 1.2 2.4e-17 63.0 1.0 1.3 1 1 0 1 1 1 1 PX domain Surfac_D-trimer PF09006.11 KFM69535.1 - 0.026 14.4 0.3 2.5 8.0 0.3 2.8 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DUF3847 PF12958.7 KFM69535.1 - 0.035 14.2 3.2 3.4 7.9 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) DUF1411 PF07199.11 KFM69535.1 - 0.036 13.7 0.1 0.042 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) ABC_tran_CTD PF16326.5 KFM69535.1 - 0.18 12.0 3.6 0.76 10.1 0.6 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Spc42p PF11544.8 KFM69535.1 - 0.57 10.2 3.9 1.5 8.9 2.4 2.2 1 1 0 1 1 1 0 Spindle pole body component Spc42p LRR_8 PF13855.6 KFM69536.1 - 2.4e-17 62.4 4.2 6.8e-09 35.4 0.7 3.5 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM69536.1 - 1.5e-10 41.1 1.3 0.00088 19.6 0.1 3.6 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM69536.1 - 6.2e-09 35.6 2.3 0.0003 20.3 0.3 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFM69536.1 - 8.5e-09 35.4 1.8 3.1e-06 27.2 0.4 2.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 KFM69537.1 - 1.1e-19 70.0 6.5 9.4e-09 34.9 0.0 4.0 3 2 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFM69537.1 - 9.5e-12 44.9 2.7 0.00032 21.0 0.0 3.7 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM69537.1 - 1.1e-07 31.5 1.6 0.0015 18.1 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFM69537.1 - 2e-07 31.0 3.5 3.2e-05 23.9 0.7 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM69537.1 - 0.0035 17.7 0.0 5.7 7.9 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 KFM69537.1 - 0.016 15.2 0.6 34 4.8 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 KFM69538.1 - 5.9e-32 109.2 31.7 5.1e-10 39.0 0.3 3.5 1 1 4 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 KFM69538.1 - 5.4e-10 39.3 1.7 2.9e-06 27.3 0.1 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM69538.1 - 7.9e-07 28.7 8.8 0.0021 17.6 2.2 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFM69538.1 - 3e-06 27.4 24.7 0.0066 16.8 0.6 4.6 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM69538.1 - 2.3 9.1 9.3 34 5.5 0.0 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 KFM69539.1 - 2.6e-18 65.5 9.5 2.1e-07 30.6 0.2 3.6 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFM69539.1 - 3.3e-09 36.9 15.4 0.0042 17.5 0.2 4.5 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM69539.1 - 4.2e-08 32.9 5.9 0.00028 20.4 1.5 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFM69539.1 - 5.2e-07 29.7 0.1 0.0004 20.3 0.0 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFM69539.1 - 0.022 14.8 4.4 34 4.8 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KFM69539.1 - 1 10.2 8.8 37 5.4 0.0 5.3 6 1 0 6 6 6 0 Leucine Rich Repeat CUB PF00431.20 KFM69540.1 - 6.3e-05 23.3 1.5 0.00086 19.6 0.0 2.4 3 0 0 3 3 3 2 CUB domain SDF PF00375.18 KFM69541.1 - 8.1e-131 436.6 28.9 9.5e-131 436.4 28.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 KFM69542.1 - 1.6e-132 442.2 27.9 1.9e-132 442.0 27.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family PI3K_rbd PF00794.18 KFM69542.1 - 0.078 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain DUF3155 PF11352.8 KFM69543.1 - 0.064 13.7 2.0 4.3 7.8 0.0 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3155) Pkinase PF00069.25 KFM69545.1 - 4.6e-24 85.2 0.0 9e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM69545.1 - 5.1e-19 68.6 0.0 4.3e-18 65.5 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 KFM69545.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family mRNA_decap_C PF16741.5 KFM69545.1 - 0.021 14.1 1.0 0.053 12.8 1.0 1.7 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus GMC_oxred_C PF05199.13 KFM69546.1 - 1.9e-19 70.6 0.4 2.6e-19 70.2 0.4 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Ald_Xan_dh_C PF01315.22 KFM69546.1 - 0.067 13.6 0.1 0.071 13.5 0.1 1.1 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain GMC_oxred_N PF00732.19 KFM69547.1 - 3.2e-29 102.3 0.0 3.4e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase HTH_Tnp_Tc3_2 PF01498.18 KFM69548.1 - 4.5e-16 58.8 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69548.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69548.1 - 2e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69548.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69548.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Peptidase_C65 PF10275.9 KFM69549.1 - 1.4e-44 152.4 0.0 1.5e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain SAICAR_synt PF01259.18 KFM69550.1 - 3.3e-54 184.2 0.1 4.4e-54 183.8 0.1 1.1 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 KFM69550.1 - 4e-28 97.9 0.0 7e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 AIR carboxylase Cnd1 PF12717.7 KFM69552.1 - 0.00082 19.4 1.0 0.0054 16.8 1.0 2.3 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Pribosyl_synth PF14572.6 KFM69556.1 - 2.7e-45 154.6 3.8 2.8e-39 135.1 1.6 2.1 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFM69556.1 - 8.8e-18 64.3 0.2 1.2e-17 63.9 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFM69556.1 - 4.2e-06 26.4 0.1 5.6e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DDE_1 PF03184.19 KFM69557.1 - 0.01 15.5 0.0 0.011 15.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease AtuA PF07287.11 KFM69558.1 - 2e-116 388.5 0.0 2.6e-116 388.2 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA BBS2_Mid PF14783.6 KFM69559.1 - 0.0017 18.4 1.4 0.13 12.3 0.0 2.5 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 KFM69559.1 - 0.031 14.6 0.1 0.16 12.3 0.0 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4683 PF15735.5 KFM69559.1 - 0.85 9.2 3.8 0.19 11.3 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4683) Med21 PF11221.8 KFM69559.1 - 1.1 9.5 6.6 2.1 8.6 0.2 2.3 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DUF1917 PF08939.10 KFM69560.1 - 0.0025 17.8 0.2 0.0081 16.1 0.0 1.8 1 1 0 2 2 2 1 Domain of unknown function (DUF1917) FERM_f0 PF16511.5 KFM69560.1 - 0.068 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM 7tm_2 PF00002.24 KFM69561.1 - 7e-16 58.3 4.5 7.2e-16 58.2 4.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Herpes_LMP1 PF05297.11 KFM69561.1 - 0.35 10.0 4.3 0.34 10.0 4.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) HTH_Tnp_Tc3_2 PF01498.18 KFM69562.1 - 3.8e-16 59.1 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69562.1 - 1.2e-13 51.0 0.0 2.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69562.1 - 3.2e-07 30.0 1.6 7.7e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69562.1 - 0.0028 17.4 0.6 0.0083 15.9 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain PLDc_2 PF13091.6 KFM69563.1 - 1.7e-13 50.6 0.0 5.6e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFM69563.1 - 0.02 15.1 1.7 1.2 9.4 0.1 3.2 2 1 0 2 2 2 0 Phospholipase D Active site motif PP-binding PF00550.25 KFM69564.1 - 1.6e-08 34.7 0.1 2.6e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KFM69564.1 - 0.019 15.2 0.1 0.031 14.5 0.1 1.4 1 0 0 1 1 1 0 Acyl-carrier Chitin_bind_4 PF00379.23 KFM69565.1 - 6.8e-12 45.7 6.3 9.8e-12 45.2 6.3 1.2 1 0 0 1 1 1 1 Insect cuticle protein TraW_N PF12477.8 KFM69565.1 - 0.34 10.9 0.2 0.34 10.9 0.2 2.3 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal HTH_Tnp_Tc3_2 PF01498.18 KFM69566.1 - 1.9e-16 60.1 2.2 4.3e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69566.1 - 8.9e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1241 PF06840.11 KFM69567.1 - 3.3e-64 215.0 0.2 3.7e-64 214.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Cas_Csn2 PF09711.10 KFM69567.1 - 0.0098 15.6 0.5 0.031 14.0 0.2 1.8 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Csn2) FmiP_Thoc5 PF09766.9 KFM69567.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 BLOC1_2 PF10046.9 KFM69567.1 - 0.032 14.5 0.4 0.058 13.7 0.1 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATP-synt_10 PF05176.14 KFM69567.1 - 0.075 12.3 0.0 0.093 12.0 0.0 1.1 1 0 0 1 1 1 0 ATP10 protein DDE_3 PF13358.6 KFM69568.1 - 6.1e-16 58.5 0.1 6.6e-15 55.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69568.1 - 8.4e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69568.1 - 0.00078 20.0 1.5 0.00078 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69568.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69568.1 - 0.018 15.2 0.1 0.069 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69568.1 - 0.038 14.0 0.4 0.038 14.0 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HECT PF00632.25 KFM69569.1 - 1.1e-93 314.1 1.1 1.4e-93 313.8 1.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Suppressor_P21 PF11479.8 KFM69569.1 - 0.14 12.4 0.0 0.72 10.1 0.0 2.2 2 0 0 2 2 2 0 RNA silencing suppressor P21 C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM69570.1 - 2.2e-19 69.4 3.8 4.9e-19 68.4 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69570.1 - 3.5e-16 59.3 0.0 1.8e-15 56.9 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM69570.1 - 2.9e-07 31.0 4.3 3.1e-07 30.9 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM69570.1 - 0.00031 20.6 0.7 0.0049 16.7 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_29 PF13551.6 KFM69570.1 - 0.00096 19.1 0.3 0.02 14.9 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM69570.1 - 0.0014 18.8 1.2 0.28 11.4 0.0 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM69570.1 - 0.0029 17.5 2.2 0.018 15.0 0.0 2.6 2 1 1 3 3 3 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KFM69570.1 - 0.022 14.5 1.8 1.1 9.1 0.0 3.0 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 KFM69570.1 - 0.029 14.5 0.7 8.3 6.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 KFM69570.1 - 0.11 12.7 0.1 19 5.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain zf-CCHC PF00098.23 KFM69571.1 - 3.3e-06 26.9 6.8 4.8e-05 23.3 1.4 2.7 3 0 0 3 3 3 2 Zinc knuckle Retrotran_gag_2 PF14223.6 KFM69571.1 - 0.0047 16.6 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 KFM69571.1 - 0.017 14.8 0.6 0.032 14.0 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle MRJP PF03022.16 KFM69571.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Major royal jelly protein HEAT_2 PF13646.6 KFM69572.1 - 4.9e-06 26.8 0.0 0.0002 21.7 0.1 2.8 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KFM69572.1 - 0.00019 21.4 2.2 0.86 10.0 0.0 4.3 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KFM69572.1 - 0.0067 16.5 0.6 0.71 9.9 0.0 3.3 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 KFM69572.1 - 0.008 16.5 0.6 19 5.7 0.4 3.9 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 KFM69572.1 - 0.053 12.7 0.2 0.35 10.0 0.1 2.2 1 1 1 2 2 2 0 Nuclear condensing complex subunits, C-term domain NRDE-2 PF08424.10 KFM69572.1 - 0.06 12.5 0.4 0.09 11.9 0.4 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Homeodomain PF00046.29 KFM69573.1 - 2.1e-23 81.9 6.7 3.2e-23 81.3 6.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM69573.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain zf-MYST PF17772.1 KFM69574.1 - 0.087 12.4 4.9 0.2 11.3 4.9 1.7 1 0 0 1 1 1 0 MYST family zinc finger domain DrsE PF02635.15 KFM69574.1 - 0.13 12.6 0.0 0.64 10.4 0.0 2.0 2 0 0 2 2 2 0 DsrE/DsrF-like family Endonuclease_7 PF02945.15 KFM69574.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.5 2 0 0 2 2 2 0 Recombination endonuclease VII SKICH PF17751.1 KFM69575.1 - 5.1e-21 75.1 0.0 1.5e-20 73.6 0.0 1.9 1 0 0 1 1 1 1 SKICH domain DUF5340 PF17275.2 KFM69575.1 - 4.5 7.5 8.1 1.6 8.9 2.0 3.5 2 1 1 3 3 3 0 Family of unknown function (DUF5340) MIT_LIKE_ACTX PF17556.2 KFM69577.1 - 0.00048 20.7 7.8 0.00048 20.7 7.8 1.5 1 1 0 1 1 1 1 MIT-like atracotoxin family Prokineticin PF06607.11 KFM69577.1 - 0.0018 18.6 8.1 0.0032 17.7 8.1 1.4 1 1 0 1 1 1 1 Prokineticin DX PF01666.17 KFM69577.1 - 0.022 15.2 6.0 0.022 15.2 6.0 2.2 2 1 0 2 2 2 0 DX module Dickkopf_N PF04706.12 KFM69577.1 - 0.45 11.0 15.6 1.9 9.1 15.6 2.1 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Nodulin_late PF07127.11 KFM69577.1 - 5.2 7.5 10.6 0.16 12.3 3.5 2.0 2 1 0 2 2 2 0 Late nodulin protein MIT_LIKE_ACTX PF17556.2 KFM69578.1 - 1.3e-06 28.9 7.3 1.3e-06 28.9 7.3 1.9 2 0 0 2 2 2 1 MIT-like atracotoxin family Prokineticin PF06607.11 KFM69578.1 - 0.0021 18.3 6.2 0.0028 17.9 6.2 1.2 1 0 0 1 1 1 1 Prokineticin Dickkopf_N PF04706.12 KFM69578.1 - 3.2 8.3 16.6 0.079 13.4 7.8 2.4 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region MIT_LIKE_ACTX PF17556.2 KFM69579.1 - 4.3e-07 30.4 8.0 6.6e-07 29.8 8.0 1.3 1 0 0 1 1 1 1 MIT-like atracotoxin family Prokineticin PF06607.11 KFM69579.1 - 0.00018 21.8 5.2 0.00021 21.5 5.2 1.1 1 0 0 1 1 1 1 Prokineticin DUF2856 PF11043.8 KFM69579.1 - 0.037 14.2 0.4 0.045 13.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Prokineticin PF06607.11 KFM69580.1 - 0.41 11.0 6.0 0.69 10.3 6.0 1.4 1 1 0 1 1 1 0 Prokineticin HlyIII PF03006.20 KFM69581.1 - 3.4e-36 125.0 8.8 5.1e-36 124.5 8.8 1.3 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.20 KFM69582.1 - 1.2e-19 71.0 4.6 1.4e-19 70.7 4.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related Urm1 PF09138.11 KFM69583.1 - 0.0093 16.3 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) Spaetzle PF16077.5 KFM69584.1 - 2.3e-24 85.8 0.2 4.6e-24 84.8 0.2 1.6 1 0 0 1 1 1 1 Spaetzle UCH PF00443.29 KFM69585.1 - 1.7e-20 73.6 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM69585.1 - 1.2e-06 28.3 3.4 2.6e-06 27.3 3.4 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SCAB-ABD PF16711.5 KFM69586.1 - 0.0024 17.7 0.0 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 Actin-binding domain of plant-specific actin-binding protein DUF1697 PF08002.11 KFM69586.1 - 0.53 10.7 2.9 0.6 10.6 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1697) HTH_23 PF13384.6 KFM69588.1 - 2.8e-08 33.3 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KFM69588.1 - 8.3e-07 28.6 0.1 9.2e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 KFM69588.1 - 3.2e-06 27.0 0.1 4.2e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_50 PF18024.1 KFM69588.1 - 2.1e-05 24.1 0.2 2.8e-05 23.6 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KFM69588.1 - 2.5e-05 24.0 0.2 3.4e-05 23.5 0.2 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM69588.1 - 2.8e-05 23.4 0.0 3.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KFM69588.1 - 3.8e-05 23.7 0.0 5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM69588.1 - 0.00035 20.0 0.1 0.00044 19.7 0.1 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 UPF0122 PF04297.14 KFM69588.1 - 0.00061 20.0 0.0 0.00069 19.8 0.0 1.1 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_24 PF13412.6 KFM69588.1 - 0.0016 18.0 0.1 0.0018 17.8 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_IS630 PF01710.16 KFM69588.1 - 0.0022 18.0 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Transposase Mor PF08765.11 KFM69588.1 - 0.0087 16.0 0.4 0.01 15.8 0.4 1.2 1 0 0 1 1 1 1 Mor transcription activator family HTH_7 PF02796.15 KFM69588.1 - 0.0098 16.0 0.2 0.016 15.3 0.2 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain of resolvase TnsD PF15978.5 KFM69588.1 - 0.0098 14.9 0.1 0.0098 14.9 0.1 1.0 1 0 0 1 1 1 1 Tn7-like transposition protein D HTH_1 PF00126.27 KFM69588.1 - 0.011 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_1 PF01527.20 KFM69588.1 - 0.011 16.0 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 0 Transposase DUF3791 PF12668.7 KFM69588.1 - 0.034 14.2 0.1 0.05 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) HTH_40 PF14493.6 KFM69588.1 - 0.04 14.4 0.1 0.045 14.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 KFM69588.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix bZIP_Maf PF03131.17 KFM69589.1 - 7e-28 97.0 14.2 1.1e-27 96.4 14.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFM69589.1 - 8.2e-06 25.8 11.6 1.3e-05 25.2 11.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM69589.1 - 0.024 14.7 11.9 0.041 14.0 11.9 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DUF1192 PF06698.11 KFM69589.1 - 0.065 13.3 3.3 1.6 8.9 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Rnk_N PF14760.6 KFM69589.1 - 0.19 12.3 0.4 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Rnk N-terminus TMF_TATA_bd PF12325.8 KFM69589.1 - 0.19 12.0 4.0 0.098 12.9 1.3 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Tctex-1 PF03645.13 KFM69593.1 - 7.8e-14 51.8 1.0 8.4e-14 51.7 1.0 1.0 1 0 0 1 1 1 1 Tctex-1 family zf-RING_2 PF13639.6 KFM69594.1 - 1.6e-05 25.1 5.4 1.6e-05 25.1 5.4 4.7 5 1 1 6 6 6 1 Ring finger domain zf-RING_UBOX PF13445.6 KFM69594.1 - 1.9e-05 24.6 5.8 1.9e-05 24.6 5.8 3.4 3 0 0 3 3 3 1 RING-type zinc-finger ubiquitin PF00240.23 KFM69594.1 - 0.00094 18.9 0.0 0.0046 16.7 0.0 2.2 1 0 0 1 1 1 1 Ubiquitin family zf-C3HC4_2 PF13923.6 KFM69594.1 - 0.001 18.8 5.1 0.001 18.8 5.1 4.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM69594.1 - 0.0016 18.2 5.1 0.0016 18.2 5.1 5.5 6 1 1 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM69594.1 - 0.006 16.5 5.4 0.006 16.5 5.4 4.9 4 1 0 4 4 4 1 zinc-RING finger domain IBR PF01485.21 KFM69594.1 - 0.007 16.6 5.0 0.007 16.6 5.0 4.6 5 0 0 5 5 5 2 IBR domain, a half RING-finger domain zf-Nse PF11789.8 KFM69594.1 - 3.5 7.5 13.6 8.5 6.3 1.0 4.4 4 0 0 4 4 4 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 KFM69594.1 - 6.5 6.6 11.2 4 7.3 7.2 2.8 2 0 0 2 2 2 0 RING-like zinc finger ORC3_N PF07034.11 KFM69596.1 - 1.7e-16 60.3 0.3 2.1e-16 60.0 0.3 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus YusW PF14039.6 KFM69596.1 - 0.082 13.4 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 YusW-like protein IceA2 PF05862.11 KFM69596.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein ORC3_N PF07034.11 KFM69597.1 - 1.4e-36 126.2 3.5 1.8e-36 125.9 3.5 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus SNAP PF14938.6 KFM69597.1 - 0.045 13.2 0.1 0.063 12.7 0.1 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP ORC_WH_C PF18137.1 KFM69598.1 - 4.7e-32 111.0 0.0 1.3e-30 106.3 0.0 2.3 1 1 0 1 1 1 1 Origin recognition complex winged helix C-terminal DUF4485 PF14846.6 KFM69598.1 - 0.079 13.0 4.0 0.19 11.8 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4485) Lectin_C PF00059.21 KFM69599.1 - 8.5e-07 29.7 0.6 2e-06 28.5 0.6 1.6 1 0 0 1 1 1 1 Lectin C-type domain WSC PF01822.19 KFM69599.1 - 1.4e-05 25.2 4.4 3.4e-05 23.9 4.4 1.7 1 0 0 1 1 1 1 WSC domain Lipocalin PF00061.23 KFM69601.1 - 1.7e-06 28.3 0.1 0.0021 18.3 0.0 2.0 2 0 0 2 2 2 2 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFM69601.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 2 0 0 2 2 2 0 Lipocalin-like domain Lipocalin_2 PF08212.12 KFM69602.1 - 9.7e-27 93.7 0.1 1.2e-26 93.4 0.1 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 KFM69602.1 - 1e-19 71.2 1.0 1.2e-19 70.9 1.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 KFM69602.1 - 1.4e-06 28.3 0.4 1.8e-06 27.9 0.4 1.2 1 0 0 1 1 1 1 Triabin DDE_3 PF13358.6 KFM69603.1 - 2.2e-05 24.2 0.0 2.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Pyrophosphatase PF00719.19 KFM69604.1 - 9e-59 197.9 0.4 1.2e-58 197.4 0.4 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase zf-CCHC PF00098.23 KFM69605.1 - 0.0037 17.3 4.3 0.0037 17.3 4.3 5.0 5 0 0 5 5 5 2 Zinc knuckle GvpL_GvpF PF06386.11 KFM69605.1 - 0.17 11.8 1.6 0.32 10.9 1.6 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF zf-CCHC_4 PF14392.6 KFM69605.1 - 5.9 6.7 36.2 0.17 11.7 0.4 5.4 4 1 1 5 5 5 0 Zinc knuckle zf-C3HC4_3 PF13920.6 KFM69606.1 - 6.1e-06 26.0 8.4 6.1e-06 26.0 8.4 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFM69606.1 - 9.3e-05 22.1 6.1 9.3e-05 22.1 6.1 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain Sina PF03145.16 KFM69606.1 - 0.004 17.1 5.6 0.0079 16.2 5.6 1.5 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4 PF00097.25 KFM69606.1 - 0.0094 15.8 5.4 0.0094 15.8 5.4 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2321 PF10083.9 KFM69606.1 - 0.012 15.2 2.5 0.027 14.1 2.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-TRAF_2 PF15965.5 KFM69606.1 - 0.017 15.6 11.1 0.017 15.6 11.1 2.0 1 1 1 2 2 2 0 TRAF-like zinc-finger zf-TRAF PF02176.18 KFM69606.1 - 0.037 14.7 5.7 0.037 14.7 5.7 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger zf-RING_14 PF17978.1 KFM69606.1 - 0.044 14.2 3.5 0.044 14.2 3.5 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFM69606.1 - 1.3 9.0 15.3 0.038 13.8 7.0 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 CBM_14 PF01607.24 KFM69607.1 - 2e-10 40.7 4.5 3.6e-10 39.9 4.5 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain SasG_E PF17041.5 KFM69607.1 - 0.025 14.6 0.1 0.072 13.1 0.1 1.7 1 0 0 1 1 1 0 E domain Inhibitor_Mig-6 PF11555.8 KFM69607.1 - 0.061 13.4 1.4 0.15 12.2 1.4 1.7 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 DUSP PF06337.12 KFM69607.1 - 0.66 10.6 5.1 3 8.5 5.1 2.2 1 1 0 1 1 1 0 DUSP domain BTB PF00651.31 KFM69608.1 - 3.4e-23 82.0 0.2 5.5e-23 81.3 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain HTH_Tnp_Tc3_2 PF01498.18 KFM69609.1 - 4.6e-16 58.8 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69609.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69609.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69609.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69609.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain BTB PF00651.31 KFM69610.1 - 1.1e-22 80.3 0.1 2.2e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain HTH_Tnp_Tc5 PF03221.16 KFM69611.1 - 0.00041 20.3 0.0 0.00053 20.0 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PCMT PF01135.19 KFM69612.1 - 4.3e-79 265.1 0.1 5.1e-79 264.9 0.1 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KFM69612.1 - 7.9e-08 32.2 0.0 1.6e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM69612.1 - 1.6e-06 28.7 0.0 3.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM69612.1 - 9.3e-06 25.1 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KFM69612.1 - 1.1e-05 26.0 0.0 2.9e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFM69612.1 - 0.00034 20.1 0.0 0.00048 19.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KFM69612.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM69612.1 - 0.0029 17.2 0.1 0.0062 16.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 KFM69612.1 - 0.0068 15.6 0.1 0.04 13.1 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_32 PF13679.6 KFM69612.1 - 0.0086 16.1 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM69612.1 - 0.044 13.6 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 KFM69612.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.13 KFM69612.1 - 0.24 10.9 0.1 1.3 8.5 0.2 2.0 1 1 1 2 2 2 0 Histone methylation protein DOT1 PhyH PF05721.13 KFM69613.1 - 9.1e-24 84.9 0.0 1.1e-23 84.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Na_Ca_ex PF01699.24 KFM69614.1 - 2.1e-49 167.3 51.1 8.6e-27 93.9 28.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein zf-B_box PF00643.24 KFM69615.1 - 7.7e-09 35.6 18.5 1.6e-08 34.5 3.7 4.7 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_4 PF15227.6 KFM69615.1 - 9.4e-07 28.9 5.9 9.4e-07 28.9 5.9 4.9 4 2 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFM69615.1 - 4.9e-06 26.5 5.0 4.9e-06 26.5 5.0 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFM69615.1 - 1e-05 25.3 3.4 1e-05 25.3 3.4 5.4 5 1 1 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM69615.1 - 3e-05 23.8 4.2 3e-05 23.8 4.2 4.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) CEBP_ZZ PF16366.5 KFM69615.1 - 0.00065 19.9 4.0 0.00065 19.9 4.0 3.4 4 1 0 4 4 4 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Zn-C2H2_12 PF18112.1 KFM69615.1 - 0.17 12.4 6.8 1.8 9.1 1.2 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_5 PF14634.6 KFM69615.1 - 3.9 7.5 37.1 0.088 12.8 7.6 5.1 4 1 1 5 5 5 0 zinc-RING finger domain zf-C4pol PF14260.6 KFM69615.1 - 8.8 6.9 28.3 0.35 11.4 1.6 4.0 3 1 1 4 4 4 0 C4-type zinc-finger of DNA polymerase delta PRY PF13765.6 KFM69617.1 - 2.1e-07 30.5 0.1 3.7e-07 29.7 0.1 1.5 1 1 1 2 2 2 1 SPRY-associated domain SPRY PF00622.28 KFM69618.1 - 1.4e-08 34.9 0.0 1.8e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 SPRY domain TBCC PF07986.12 KFM69620.1 - 2.4e-44 149.9 1.5 3.9e-44 149.2 1.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KFM69620.1 - 2.1e-28 99.1 6.2 3.2e-28 98.5 6.2 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain CAP_C PF08603.11 KFM69620.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal DUF2205 PF10224.9 KFM69620.1 - 0.12 12.4 1.9 2.4 8.2 0.3 2.5 2 0 0 2 2 2 0 Short coiled-coil protein HTH_11 PF08279.12 KFM69620.1 - 0.2 11.7 0.0 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 HTH domain Baculo_LEF-2 PF03041.14 KFM69620.1 - 3 7.5 7.5 0.38 10.4 0.4 2.5 2 1 0 2 2 2 0 lef-2 Methyltransf_23 PF13489.6 KFM69621.1 - 1.3e-06 28.3 0.0 5.1e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KFM69621.1 - 0.008 16.9 0.2 1.1 10.0 0.1 2.4 1 1 1 2 2 2 2 Methyltransferase domain CoA_transf_3 PF02515.17 KFM69622.1 - 2.3e-122 408.7 0.0 2.7e-122 408.5 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III SAM_4 PF18017.1 KFM69622.1 - 0.0065 16.4 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RRM_1 PF00076.22 KFM69623.1 - 3.8e-05 23.4 0.1 7.9e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_3 PF13358.6 KFM69624.1 - 7.6e-16 58.2 0.1 8.4e-15 54.8 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69624.1 - 8.2e-16 58.0 6.5 1.4e-15 57.3 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69624.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69624.1 - 0.0024 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69624.1 - 0.015 15.4 0.1 0.063 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69624.1 - 0.034 14.2 0.4 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DUF4371 PF14291.6 KFM69625.1 - 3.9e-10 39.8 0.0 7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) HTH_Tnp_Tc3_2 PF01498.18 KFM69626.1 - 2.3e-16 59.8 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69626.1 - 9.9e-14 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69627.1 - 4.2e-16 58.9 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69627.1 - 1.1e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69627.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69627.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69627.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM69628.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69628.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69628.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69628.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69628.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Aldolase_II PF00596.21 KFM69629.1 - 8.5e-43 146.4 0.1 1.8e-42 145.4 0.1 1.6 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GerD PF17898.1 KFM69629.1 - 0.027 14.4 1.7 0.19 11.7 0.5 2.8 2 0 0 2 2 2 0 Spore germination GerD central core domain RelE PF06296.12 KFM69629.1 - 0.047 13.8 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system MEF2_binding PF09047.10 KFM69629.1 - 0.2 11.5 2.2 3.4 7.6 0.3 2.8 2 0 0 2 2 2 0 MEF2 binding Claudin_2 PF13903.6 KFM69632.1 - 0.0023 17.7 9.5 0.0031 17.3 9.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 KFM69632.1 - 0.005 16.8 8.4 0.052 13.5 8.3 2.1 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Amastin PF07344.11 KFM69632.1 - 0.024 14.5 6.9 0.036 13.9 6.9 1.3 1 1 0 1 1 1 0 Amastin surface glycoprotein NPCC PF08058.11 KFM69632.1 - 0.17 11.9 2.3 0.38 10.8 2.3 1.6 1 1 0 1 1 1 0 Nuclear pore complex component Phage_Gp23 PF10669.9 KFM69632.1 - 0.78 10.1 2.7 5.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) SUR7 PF06687.12 KFM69632.1 - 2.9 7.4 9.4 8.8 5.9 9.4 1.7 1 1 0 1 1 1 0 SUR7/PalI family HTH_Tnp_Tc3_2 PF01498.18 KFM69634.1 - 4.8e-15 55.6 0.2 1.2e-14 54.2 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM69634.1 - 0.00012 22.2 4.5 0.00021 21.4 0.1 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM69634.1 - 0.00075 19.5 4.1 0.0021 18.0 0.2 3.0 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.6 KFM69634.1 - 0.0038 17.0 2.0 0.032 14.0 0.0 3.2 4 0 0 4 4 4 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KFM69634.1 - 0.0058 16.0 0.5 0.11 11.9 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_20 PF12840.7 KFM69634.1 - 0.015 15.3 0.0 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KFM69634.1 - 0.052 13.9 0.3 0.11 12.8 0.3 1.6 1 0 0 1 1 1 0 Transposase MarR_2 PF12802.7 KFM69634.1 - 0.081 12.8 1.0 0.2 11.6 0.0 2.2 3 0 0 3 3 3 0 MarR family CENP-B_N PF04218.13 KFM69634.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 KFM69634.1 - 8.2 7.1 9.0 8.7 7.0 0.5 2.8 2 1 1 3 3 3 0 Homeodomain-like domain S8_pro-domain PF16470.5 KFM69635.1 - 1.3e-15 58.0 0.2 1.5e-15 57.7 0.2 1.1 1 0 0 1 1 1 1 Peptidase S8 pro-domain c-SKI_SMAD_bind PF08782.10 KFM69635.1 - 0.022 15.0 0.1 0.023 14.9 0.1 1.2 1 0 0 1 1 1 0 c-SKI Smad4 binding domain Sgf11 PF08209.11 KFM69635.1 - 0.041 13.5 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Peptidase_S8 PF00082.22 KFM69636.1 - 2.7e-24 86.0 0.4 1.5e-23 83.5 0.8 1.8 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 KFM69636.1 - 1.1e-22 79.9 0.0 2.1e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Furin-like_2 PF15913.5 KFM69636.1 - 1.1e-12 48.0 150.9 7e-06 26.2 10.7 8.7 1 1 7 8 8 8 6 Furin-like repeat, cysteine-rich VSP PF03302.13 KFM69636.1 - 4.4e-09 35.7 133.5 0.0055 15.6 6.2 7.9 1 1 4 6 6 6 6 Giardia variant-specific surface protein GF_recep_IV PF14843.6 KFM69636.1 - 1.6e-06 27.9 153.4 0.0011 18.7 28.3 6.5 1 1 5 6 6 6 3 Growth factor receptor domain IV DNA_pol_E_B PF04042.16 KFM69638.1 - 3.7e-39 134.3 0.2 7.3e-39 133.3 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KFM69638.1 - 1.7e-08 34.8 0.0 4.1e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DUF4371 PF14291.6 KFM69639.1 - 1e-07 31.8 0.3 2.1e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) UPF0122 PF04297.14 KFM69639.1 - 0.097 12.9 2.0 5.9 7.2 0.3 3.0 3 0 0 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like Mto2_bdg PF12808.7 KFM69640.1 - 0.0039 17.5 2.9 0.0039 17.5 2.9 2.0 2 0 0 2 2 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Tup_N PF08581.10 KFM69640.1 - 0.021 15.1 1.2 0.021 15.1 1.2 2.0 2 0 0 2 2 2 0 Tup N-terminal TEX13 PF15186.6 KFM69640.1 - 0.12 12.0 2.6 0.14 11.8 2.6 1.2 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF3987 PF13148.6 KFM69640.1 - 0.59 9.1 4.7 0.64 9.0 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) HTH_Tnp_Tc3_2 PF01498.18 KFM69641.1 - 4.3e-10 39.7 0.3 9.2e-10 38.6 0.3 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69641.1 - 1.4e-08 34.6 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_21 PF13276.6 KFM69641.1 - 0.024 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 HTH-like domain HTH_33 PF13592.6 KFM69641.1 - 0.073 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix fn3 PF00041.21 KFM69643.1 - 2.8e-10 40.4 0.3 7.8e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III domain GtrA PF04138.14 KFM69643.1 - 0.022 15.0 0.4 0.033 14.4 0.4 1.2 1 0 0 1 1 1 0 GtrA-like protein Codanin-1_C PF15296.6 KFM69644.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Codanin-1 C-terminus Ig_3 PF13927.6 KFM69645.1 - 6.3e-14 52.3 0.0 9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM69645.1 - 3.4e-11 43.1 0.0 1.1e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFM69645.1 - 2.9e-09 37.1 0.0 3.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM69645.1 - 1.7e-08 34.7 0.0 6.8e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM69645.1 - 4.4e-08 33.2 0.0 5.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM69645.1 - 0.0048 16.9 0.1 0.0062 16.6 0.1 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.16 KFM69645.1 - 0.029 13.1 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ig_3 PF13927.6 KFM69646.1 - 0.0027 18.3 0.0 0.0034 18.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM69646.1 - 0.005 17.0 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain DUF4600 PF15372.6 KFM69647.1 - 1.1e-19 71.1 5.0 1.1e-19 71.1 5.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4600) RT_RNaseH PF17917.1 KFM69647.1 - 1.1e-15 57.7 0.3 3.5e-15 56.2 0.3 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM69647.1 - 3.9e-15 56.0 0.1 1e-14 54.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFM69647.1 - 1.9e-09 37.4 0.2 1.1e-08 35.0 0.2 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KFM69647.1 - 0.00039 20.6 0.0 0.00092 19.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 KFM69647.1 - 0.043 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM69647.1 - 0.054 14.1 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF4686 PF15742.5 KFM69648.1 - 0.0012 18.1 2.6 0.0013 18.0 2.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) DUF3618 PF12277.8 KFM69648.1 - 0.028 14.7 2.6 2.8 8.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Spc29 PF17082.5 KFM69648.1 - 0.031 14.1 1.3 0.033 14.0 1.3 1.0 1 0 0 1 1 1 0 Spindle Pole Component 29 BST2 PF16716.5 KFM69648.1 - 0.037 14.6 1.9 0.039 14.5 1.9 1.1 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 FlaC_arch PF05377.11 KFM69648.1 - 0.076 13.4 1.7 0.14 12.6 1.7 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 KFM69648.1 - 0.16 12.1 4.1 0.47 10.5 2.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Asp PF00026.23 KFM69649.1 - 5.3e-127 423.6 0.4 6e-127 423.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFM69649.1 - 7.2e-17 62.2 1.4 7.6e-15 55.6 1.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KFM69649.1 - 9.3e-06 25.5 0.0 3.2e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KFM69649.1 - 0.0017 18.9 0.1 1.2 9.9 0.1 3.2 2 1 0 2 2 2 1 Aspartyl protease LRR_9 PF14580.6 KFM69650.1 - 1.4e-07 31.2 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFM69650.1 - 1.9e-05 24.9 0.5 0.0027 18.1 0.0 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM69650.1 - 0.0002 21.1 0.4 0.0037 17.2 0.0 2.6 3 0 0 3 3 3 1 Leucine Rich repeat LRR_8 PF13855.6 KFM69650.1 - 0.00039 20.1 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 Leucine rich repeat PWI PF01480.17 KFM69653.1 - 4.4e-13 49.3 0.4 1.3e-12 47.9 0.4 1.9 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KFM69653.1 - 2e-08 33.9 0.0 4.3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bZIP_1 PF00170.21 KFM69654.1 - 0.00041 20.4 6.8 0.012 15.6 0.8 2.2 2 0 0 2 2 2 2 bZIP transcription factor DUF1664 PF07889.12 KFM69654.1 - 0.0028 17.7 2.1 0.0031 17.5 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Atg14 PF10186.9 KFM69654.1 - 0.0035 16.5 10.5 0.0036 16.5 10.5 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Med2 PF11214.8 KFM69654.1 - 0.0047 17.1 2.7 0.0053 16.9 2.5 1.2 1 1 0 1 1 1 1 Mediator complex subunit 2 ADIP PF11559.8 KFM69654.1 - 0.0071 16.4 10.4 0.0076 16.3 10.4 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 KFM69654.1 - 0.012 15.6 7.2 0.015 15.4 7.2 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KFM69654.1 - 0.017 15.3 8.8 0.76 10.1 0.9 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ax_dynein_light PF10211.9 KFM69654.1 - 0.018 15.0 8.3 0.02 14.8 8.3 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain vATP-synt_E PF01991.18 KFM69654.1 - 0.019 14.4 6.3 0.021 14.2 6.3 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit HMMR_C PF15908.5 KFM69654.1 - 0.019 15.2 5.3 0.027 14.7 5.3 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal KASH_CCD PF14662.6 KFM69654.1 - 0.021 14.7 7.8 0.024 14.4 7.8 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4404 PF14357.6 KFM69654.1 - 0.022 15.4 5.7 0.022 15.4 5.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ATG16 PF08614.11 KFM69654.1 - 0.027 14.7 9.5 0.03 14.5 9.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Med9 PF07544.13 KFM69654.1 - 0.028 14.5 2.3 0.028 14.5 2.3 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_2 PF07716.15 KFM69654.1 - 0.03 14.4 6.8 0.68 10.1 1.3 2.5 2 0 0 2 2 2 0 Basic region leucine zipper JAKMIP_CC3 PF16034.5 KFM69654.1 - 0.033 14.1 5.0 0.051 13.5 5.0 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain Fungal_TACC PF12709.7 KFM69654.1 - 0.034 14.6 5.4 0.7 10.4 5.4 2.1 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1465 PF07323.12 KFM69654.1 - 0.047 13.5 2.7 0.051 13.4 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) COG2 PF06148.11 KFM69654.1 - 0.056 13.5 3.8 0.035 14.2 1.9 1.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TolA_bind_tri PF16331.5 KFM69654.1 - 0.062 13.4 7.4 0.082 13.0 7.4 1.4 1 1 0 1 1 1 0 TolA binding protein trimerisation Mod_r PF07200.13 KFM69654.1 - 0.063 13.4 7.6 0.075 13.1 7.6 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2203 PF09969.9 KFM69654.1 - 0.064 14.0 2.2 0.078 13.7 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 KFM69654.1 - 0.094 13.0 7.8 0.097 13.0 7.8 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 KFM69654.1 - 0.095 13.1 6.6 1.6 9.1 1.3 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMCO5 PF14992.6 KFM69654.1 - 0.1 12.1 6.6 0.12 12.0 6.6 1.1 1 0 0 1 1 1 0 TMCO5 family APG6_N PF17675.1 KFM69654.1 - 0.12 12.9 8.2 0.13 12.8 8.2 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Snapin_Pallidin PF14712.6 KFM69654.1 - 0.13 12.6 7.5 0.45 11.0 7.5 1.8 1 1 0 1 1 1 0 Snapin/Pallidin YabA PF06156.13 KFM69654.1 - 0.15 12.7 6.2 0.41 11.3 4.1 2.0 1 1 1 2 2 2 0 Initiation control protein YabA NPV_P10 PF05531.12 KFM69654.1 - 0.17 12.4 4.2 0.27 11.7 4.2 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Uso1_p115_C PF04871.13 KFM69654.1 - 0.31 11.4 9.8 0.43 11.0 9.8 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.8 KFM69654.1 - 0.32 10.3 8.5 0.33 10.2 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 KFM69654.1 - 0.34 9.8 7.8 0.36 9.6 7.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 KFM69654.1 - 0.41 9.1 0.8 0.39 9.2 0.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSCB_C PF07743.13 KFM69654.1 - 0.44 11.1 4.2 0.53 10.8 1.4 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain ZapB PF06005.12 KFM69654.1 - 0.65 10.5 12.0 1.9 9.0 10.7 2.0 1 1 1 2 2 2 0 Cell division protein ZapB UPF0449 PF15136.6 KFM69654.1 - 1.3 9.6 7.7 14 6.2 7.7 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 TMPIT PF07851.13 KFM69654.1 - 1.5 8.0 5.9 1.6 7.9 5.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 KFM69654.1 - 1.7 8.5 10.7 4.2 7.2 1.2 2.1 1 1 1 2 2 2 0 Septum formation initiator UPF0449 PF15136.6 KFM69656.1 - 4.4e-15 56.0 1.0 5.6e-15 55.6 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 tRNA-synt_2 PF00152.20 KFM69657.1 - 1.2e-90 303.8 0.0 1.5e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFM69657.1 - 1.2e-09 38.0 0.6 2.4e-09 37.1 0.6 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 KFM69657.1 - 2.6e-08 34.0 0.0 5.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 KFM69657.1 - 0.022 14.3 0.2 0.049 13.1 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Methyltransf_23 PF13489.6 KFM69658.1 - 1.4e-08 34.7 0.0 1.9e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM69658.1 - 4.6e-07 30.5 0.0 8.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM69658.1 - 0.0001 22.9 0.0 0.0002 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM69658.1 - 0.00022 21.9 0.0 0.00042 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM69658.1 - 0.00044 20.1 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFM69658.1 - 0.02 14.8 0.0 0.056 13.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Ins134_P3_kin PF05770.11 KFM69658.1 - 0.062 12.8 0.1 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Pkinase PF00069.25 KFM69659.1 - 9.4e-59 198.9 0.0 1.8e-58 198.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM69659.1 - 9.7e-43 146.3 0.0 1.6e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM69659.1 - 1.9e-08 34.0 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM69659.1 - 0.00016 20.8 0.0 0.0018 17.3 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFM69659.1 - 0.00037 19.6 0.1 0.00072 18.7 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KFM69659.1 - 0.0034 17.3 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM69659.1 - 0.015 14.1 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KFM69659.1 - 0.056 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 KFM69659.1 - 0.058 12.7 0.0 0.72 9.2 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM69659.1 - 0.095 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Ins145_P3_rec PF08709.11 KFM69659.1 - 0.099 11.8 0.0 0.35 10.0 0.0 1.8 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Ferric_reduct PF01794.19 KFM69661.1 - 0.064 13.4 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Syndecan PF01034.20 KFM69661.1 - 0.33 10.9 1.1 2.7 8.0 0.2 2.3 2 0 0 2 2 2 0 Syndecan domain gag-asp_proteas PF13975.6 KFM69664.1 - 0.00023 21.7 0.0 0.00041 20.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM69664.1 - 0.00039 21.0 0.0 0.00071 20.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Apolipoprotein PF01442.18 KFM69665.1 - 0.00033 20.6 5.2 0.00044 20.2 5.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1451 PF07295.11 KFM69665.1 - 0.0038 17.3 6.9 0.0054 16.8 6.2 1.5 1 1 0 1 1 1 1 Zinc-ribbon containing domain KH_5 PF13184.6 KFM69665.1 - 0.007 16.4 0.5 0.015 15.4 0.5 1.6 1 0 0 1 1 1 1 NusA-like KH domain Golgin_A5 PF09787.9 KFM69665.1 - 0.01 15.3 9.2 0.012 15.0 9.2 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phasin PF05597.11 KFM69665.1 - 0.012 15.6 9.1 0.012 15.6 9.1 1.4 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 KFM69665.1 - 0.019 15.0 6.9 0.29 11.2 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 KFM69665.1 - 0.033 14.3 5.3 0.041 13.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Prominin PF05478.11 KFM69665.1 - 0.036 12.1 1.8 0.037 12.0 1.8 1.0 1 0 0 1 1 1 0 Prominin DUF842 PF05811.13 KFM69665.1 - 0.053 13.2 2.9 0.52 10.0 2.0 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF4635 PF15466.6 KFM69665.1 - 0.071 12.6 2.1 0.11 12.0 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Tox-ODYAM1 PF15642.6 KFM69665.1 - 0.12 11.3 5.5 0.14 11.1 5.5 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Fib_alpha PF08702.10 KFM69665.1 - 0.16 12.2 4.2 0.2 11.8 4.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 KFM69665.1 - 0.17 11.4 2.9 0.23 11.0 2.6 1.3 1 1 0 1 1 1 0 fzo-like conserved region ApoO PF09769.9 KFM69665.1 - 0.22 11.5 1.0 0.77 9.7 0.6 2.0 1 1 1 2 2 2 0 Apolipoprotein O HIP1_clath_bdg PF16515.5 KFM69665.1 - 0.43 11.2 9.1 0.38 11.4 3.2 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4666 PF15697.5 KFM69665.1 - 0.69 10.6 6.1 2.7 8.7 6.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) COG2 PF06148.11 KFM69665.1 - 2.5 8.2 10.0 1.3 9.2 2.1 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.13 KFM69665.1 - 4.6 7.9 6.9 8.2 7.1 4.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FlaC_arch PF05377.11 KFM69665.1 - 5 7.6 8.4 60 4.1 0.0 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Cpn60_TCP1 PF00118.24 KFM69666.1 - 2.4e-163 544.3 9.4 2.9e-163 544.0 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TFIIIC_delta PF12657.7 KFM69667.1 - 1.8e-11 44.3 0.2 3.9e-11 43.2 0.2 1.6 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KFM69667.1 - 2.6e-07 30.5 6.0 2.6e-07 30.5 6.0 2.5 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex BRF1 PF07741.13 KFM69667.1 - 0.15 12.5 5.2 0.27 11.6 5.2 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain AP3D1 PF06375.11 KFM69667.1 - 0.58 10.4 6.2 1.1 9.5 6.2 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 FAM117 PF15388.6 KFM69668.1 - 1.4e-53 182.4 17.5 3.6e-51 174.5 17.5 2.0 1 1 0 1 1 1 1 Protein Family FAM117 DDE_3 PF13358.6 KFM69669.1 - 2.2e-06 27.5 0.0 2.3e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M13_N PF05649.13 KFM69672.1 - 1.8e-21 77.3 0.4 1.9e-21 77.2 0.4 1.0 1 0 0 1 1 1 1 Peptidase family M13 DDE_3 PF13358.6 KFM69672.1 - 2.8e-05 23.9 0.0 7.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM69674.1 - 7.1e-12 45.3 0.0 7.1e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease An_peroxidase PF03098.15 KFM69675.1 - 1.1e-23 83.6 0.0 1.5e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Sprouty PF05210.13 KFM69676.1 - 5.4e-31 107.0 20.6 8.6e-31 106.4 20.6 1.3 1 0 0 1 1 1 1 Sprouty protein (Spry) WH1 PF00568.23 KFM69676.1 - 1.1e-12 47.8 0.0 2.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 WH1 domain IMS PF00817.20 KFM69677.1 - 5.3e-40 136.8 0.0 1.3e-39 135.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFM69677.1 - 8e-14 52.3 0.0 2.9e-13 50.6 0.0 2.0 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 KFM69677.1 - 1.6e-12 47.6 0.2 2.9e-12 46.8 0.2 1.4 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain BRCT_2 PF16589.5 KFM69677.1 - 1.2e-06 28.9 0.0 4.2e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 KFM69677.1 - 5.3e-06 26.4 0.0 2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.26 KFM69677.1 - 2.7e-05 24.5 3.4 0.00051 20.4 0.2 3.8 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFM69677.1 - 0.0019 18.5 0.1 0.0074 16.6 0.1 2.1 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain DUF1805 PF08827.11 KFM69677.1 - 0.0054 17.0 0.0 0.08 13.3 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1805) Cdd1 PF11731.8 KFM69677.1 - 0.0063 16.7 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Pathogenicity locus UBM PF14377.6 KFM69677.1 - 0.0072 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin binding region mCpol PF18182.1 KFM69677.1 - 0.08 13.3 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 minimal CRISPR polymerase domain HTH_Tnp_Tc3_2 PF01498.18 KFM69679.1 - 3.8e-15 55.9 2.1 9.4e-15 54.6 0.9 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69679.1 - 1.6e-12 47.4 0.0 2.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.18 KFM69679.1 - 8.9e-06 25.6 0.1 2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.6 KFM69679.1 - 1.1e-05 25.5 5.0 0.00011 22.2 0.4 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM69679.1 - 0.00025 21.6 14.1 0.0026 18.3 5.0 3.4 3 1 0 3 3 3 2 Homeodomain-like domain HTH_23 PF13384.6 KFM69679.1 - 0.0003 20.5 1.7 0.021 14.6 0.1 3.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 KFM69679.1 - 0.0015 18.2 0.2 0.0015 18.2 0.2 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM69679.1 - 0.0068 16.4 2.0 0.056 13.5 0.3 2.5 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM69679.1 - 0.011 15.6 2.2 0.043 13.7 0.1 2.7 3 0 0 3 3 3 0 MarR family TrmB PF01978.19 KFM69679.1 - 0.095 12.6 0.1 1.6 8.7 0.0 2.5 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_3 PF01381.22 KFM69679.1 - 0.12 12.5 0.8 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_37 PF13744.6 KFM69679.1 - 0.21 11.6 0.1 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 KFM69679.1 - 0.98 9.6 3.2 2.3 8.4 1.1 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KFM69680.1 - 5.2e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69680.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69680.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69680.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69680.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM69681.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69681.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69681.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69681.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69681.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_1 PF03184.19 KFM69682.1 - 4.6e-50 169.7 0.1 8.4e-50 168.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM69682.1 - 2.2e-12 46.8 0.0 1.7e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM69682.1 - 0.001 18.7 0.0 0.0033 17.0 0.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DUF659 PF04937.15 KFM69683.1 - 0.00019 21.3 0.2 0.00064 19.6 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM69683.1 - 0.00031 20.4 0.3 0.0012 18.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) AAA_12 PF13087.6 KFM69684.1 - 4.9e-35 121.0 0.5 1.1e-34 119.9 0.5 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM69684.1 - 5.6e-24 85.3 0.3 8.9e-23 81.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM69684.1 - 3.6e-10 40.3 0.1 1.5e-09 38.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM69684.1 - 8.6e-09 35.4 0.0 5.7e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KFM69684.1 - 0.00015 21.1 0.0 0.00032 20.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFM69684.1 - 0.0007 19.6 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFM69684.1 - 0.009 15.5 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 KFM69684.1 - 0.0094 15.5 0.0 0.032 13.7 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KFM69684.1 - 0.024 14.4 0.0 0.21 11.3 0.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 KFM69684.1 - 0.073 13.5 0.1 0.4 11.1 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PCAF_N PF06466.11 KFM69685.1 - 6.8e-30 104.4 1.3 8.8e-30 104.1 1.3 1.1 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Band_7 PF01145.25 KFM69687.1 - 3.4e-18 66.3 0.2 6.4e-18 65.4 0.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family Tub PF01167.18 KFM69687.1 - 0.19 11.5 4.2 0.47 10.2 3.5 1.8 1 1 1 2 2 2 0 Tub family IFRD PF05004.13 KFM69689.1 - 0.028 13.5 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KFM69691.1 - 0.00021 21.6 0.0 0.0027 18.0 0.0 2.5 3 0 0 3 3 3 1 HEAT repeats RNA_binding PF01877.17 KFM69694.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA binding TPR_2 PF07719.17 KFM69697.1 - 0.023 14.8 0.0 0.37 11.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat bZIP_2 PF07716.15 KFM69697.1 - 0.63 10.2 8.3 1.8 8.7 2.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper CUB PF00431.20 KFM69698.1 - 5.4e-16 58.9 0.2 8.7e-09 35.7 0.1 3.8 3 0 0 3 3 3 3 CUB domain Ldl_recept_a PF00057.18 KFM69698.1 - 4.2e-09 36.5 9.8 1.3e-08 34.9 9.8 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A rve PF00665.26 KFM69699.1 - 5e-13 49.3 0.0 8e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF4771 PF15995.5 KFM69699.1 - 0.023 14.9 0.2 0.029 14.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) YARHG PF13308.6 KFM69699.1 - 0.038 13.9 0.1 0.074 13.0 0.0 1.5 2 0 0 2 2 2 0 YARHG domain Asp_protease_2 PF13650.6 KFM69702.1 - 3.4e-07 30.8 0.0 4.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM69702.1 - 3.6e-06 27.4 0.0 5.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Pput2613-deam PF14427.6 KFM69702.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Pput_2613-like deaminase GCV_T PF01571.21 KFM69704.1 - 1.6e-10 40.8 0.0 2.4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain LIM PF00412.22 KFM69706.1 - 1.1e-46 156.8 40.7 3.5e-13 49.5 8.9 4.2 4 0 0 4 4 4 4 LIM domain DUF4749 PF15936.5 KFM69706.1 - 5.6e-16 59.5 1.0 1.7e-15 57.9 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFM69706.1 - 2.5e-13 50.2 0.2 5.1e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM69706.1 - 6.3e-10 38.8 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM69706.1 - 0.00019 21.7 0.0 0.00043 20.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF4746 PF15928.5 KFM69707.1 - 0.057 12.8 17.4 0.074 12.5 17.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2052 PF09747.9 KFM69707.1 - 0.1 12.7 16.6 0.14 12.2 16.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NOA36 PF06524.12 KFM69707.1 - 0.12 11.6 11.1 0.15 11.4 11.1 1.1 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 KFM69707.1 - 0.22 11.8 16.5 0.3 11.3 16.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4820 PF16091.5 KFM69707.1 - 0.56 9.5 5.0 0.69 9.2 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Myc_N PF01056.18 KFM69707.1 - 0.61 9.9 12.1 0.93 9.3 12.1 1.4 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.11 KFM69707.1 - 0.61 10.1 11.6 0.81 9.7 11.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleo_P87 PF07267.11 KFM69707.1 - 0.67 8.7 4.5 0.67 8.7 4.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.12 KFM69707.1 - 0.72 8.0 15.1 0.78 7.9 15.1 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KFM69707.1 - 2.1 7.9 16.3 2.6 7.5 16.3 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 KFM69707.1 - 2.1 6.5 11.4 2.4 6.4 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 KFM69707.1 - 2.2 7.2 19.3 2.8 6.9 19.3 1.1 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.14 KFM69707.1 - 3.2 7.5 13.9 5.2 6.8 13.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP_sp32 PF07222.12 KFM69707.1 - 5 6.5 14.8 7.3 6.0 14.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TFB6 PF17110.5 KFM69707.1 - 8.6 6.1 10.3 12 5.6 10.3 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH JMY PF15871.5 KFM69708.1 - 2.2e-75 254.2 18.8 4.4e-75 253.2 18.8 1.5 1 1 0 1 1 1 1 Junction-mediating and -regulatory protein WHAMM-JMY_N PF15920.5 KFM69708.1 - 1e-11 44.5 0.2 2.7e-11 43.1 0.2 1.7 1 0 0 1 1 1 1 N-terminal of Junction-mediating and WASP homolog-associated Ribosomal_L13e PF01294.18 KFM69709.1 - 0.0079 16.1 1.3 0.017 15.0 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L13e p450 PF00067.22 KFM69710.1 - 2.1e-84 283.9 0.0 2.4e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_Tnp_Tc3_2 PF01498.18 KFM69712.1 - 2.2e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69712.1 - 9.3e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Chitin_synth_2 PF03142.15 KFM69713.1 - 5.9e-15 54.9 1.7 1.1e-10 40.8 0.4 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFM69713.1 - 1.8e-05 24.8 1.8 1.8e-05 24.8 1.8 2.0 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Cauli_AT PF03233.13 KFM69713.1 - 0.31 10.9 3.1 0.25 11.2 0.6 2.2 2 0 0 2 2 2 0 Aphid transmission protein S1FA PF04689.13 KFM69713.1 - 6.1 7.1 6.0 4.1 7.6 1.6 2.7 2 0 0 2 2 2 0 DNA binding protein S1FA HTH_Tnp_Tc3_2 PF01498.18 KFM69715.1 - 3.9e-16 59.1 3.5 5.6e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69715.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69715.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69715.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69715.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RT_RNaseH_2 PF17919.1 KFM69716.1 - 3.8e-36 123.1 0.0 8.9e-36 121.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM69716.1 - 8.8e-31 106.3 0.0 2.2e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM69716.1 - 5.3e-23 81.7 0.0 1.1e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KFM69716.1 - 6.8e-19 67.7 0.6 2e-18 66.2 0.6 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM69716.1 - 3.3e-17 62.8 0.0 8.8e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain SCAN PF02023.17 KFM69716.1 - 2.1e-05 24.3 0.9 7.1e-05 22.5 0.9 2.0 1 0 0 1 1 1 1 SCAN domain zf-H2C2 PF09337.10 KFM69716.1 - 9.4e-05 22.6 0.0 0.0011 19.1 0.0 2.6 2 0 0 2 2 2 1 H2C2 zinc finger zf-CCHC PF00098.23 KFM69716.1 - 0.00065 19.7 0.3 0.0019 18.2 0.3 1.9 1 0 0 1 1 1 1 Zinc knuckle ATG11 PF10377.9 KFM69716.1 - 1.4 9.0 7.8 0.24 11.5 0.1 3.2 3 0 0 3 3 3 0 Autophagy-related protein 11 DUF4371 PF14291.6 KFM69717.1 - 5.5e-10 39.3 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DAO PF01266.24 KFM69718.1 - 3.5e-22 79.5 0.0 4.3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM69718.1 - 0.0014 17.8 0.1 0.0022 17.1 0.1 1.4 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KFM69718.1 - 0.0025 17.2 0.1 0.003 17.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KFM69718.1 - 0.0047 16.0 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KFM69718.1 - 0.024 13.9 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_34 PF11312.8 KFM69718.1 - 0.037 13.3 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase 3HCDH_N PF02737.18 KFM69718.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO_C PF16901.5 KFM69719.1 - 9.2e-41 138.7 0.1 2.1e-40 137.5 0.1 1.6 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase DAO PF01266.24 KFM69719.1 - 5.5e-18 65.7 0.0 8.5e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.6 KFM69719.1 - 7e-12 45.6 0.4 2.5e-11 43.8 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM69719.1 - 1.9e-09 36.4 0.1 0.0027 17.1 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFM69719.1 - 3.9e-07 29.8 0.2 6.6e-06 25.9 0.1 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM69719.1 - 2.8e-06 26.8 0.1 0.0012 18.6 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KFM69719.1 - 4.4e-05 22.8 0.1 0.19 11.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KFM69719.1 - 0.0033 17.7 0.1 0.0075 16.6 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain FliX PF10768.9 KFM69719.1 - 0.018 15.6 0.1 0.042 14.4 0.1 1.6 1 0 0 1 1 1 0 Class II flagellar assembly regulator EFhand_Ca_insen PF08726.10 KFM69719.1 - 0.023 14.8 0.1 0.074 13.2 0.0 2.0 2 0 0 2 2 1 0 Ca2+ insensitive EF hand HTH_Tnp_Tc3_2 PF01498.18 KFM69719.1 - 0.054 13.8 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Transposase SPARC_Ca_bdg PF10591.9 KFM69719.1 - 0.066 13.5 0.4 0.12 12.6 0.4 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFM69719.1 - 0.077 13.2 0.1 0.3 11.3 0.0 2.1 2 0 0 2 2 1 0 Dockerin type I domain EF-hand_4 PF12763.7 KFM69719.1 - 0.11 12.5 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF745 PF05335.13 KFM69721.1 - 0.17 11.6 4.7 0.23 11.2 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 KFM69721.1 - 0.23 11.0 8.6 0.44 10.1 8.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit HEPN_Cthe2314 PF18730.1 KFM69723.1 - 0.0076 16.3 0.6 0.0076 16.3 0.6 1.1 1 0 0 1 1 1 1 Cthe_2314-like HEPN EamA PF00892.20 KFM69726.1 - 8.6e-11 42.2 34.9 1.6e-08 34.8 15.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF1835 PF08874.10 KFM69727.1 - 0.14 12.3 0.1 0.2 11.9 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1835) DUF3987 PF13148.6 KFM69728.1 - 4.3e-11 42.4 0.1 2.7e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) Corona_NS1 PF06145.11 KFM69728.1 - 0.11 12.0 0.2 0.38 10.3 0.2 1.8 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 RRF PF01765.19 KFM69729.1 - 7e-37 126.9 8.1 1.7e-36 125.7 5.5 2.0 2 0 0 2 2 2 1 Ribosome recycling factor RNA_pol_Rpb1_1 PF04997.12 KFM69729.1 - 0.00076 18.9 2.1 0.0017 17.8 2.1 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 HTH_32 PF13565.6 KFM69729.1 - 0.0098 16.5 0.1 0.022 15.3 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DUF733 PF05306.11 KFM69729.1 - 0.3 11.4 7.7 0.67 10.3 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF733) RraB PF06877.11 KFM69729.1 - 0.45 11.3 3.1 1 10.1 0.5 2.3 2 1 0 2 2 2 0 Regulator of ribonuclease activity B YtxH PF12732.7 KFM69729.1 - 0.87 10.2 4.5 0.85 10.2 0.5 2.4 2 1 0 2 2 2 0 YtxH-like protein CCDC-167 PF15188.6 KFM69729.1 - 2.5 8.5 8.5 0.9 9.9 0.3 2.7 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 AAA_23 PF13476.6 KFM69730.1 - 2.3e-14 54.4 42.3 9.1e-09 36.1 42.3 3.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFM69730.1 - 2e-10 40.5 15.5 7.1e-10 38.7 15.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KFM69730.1 - 1.5e-05 24.9 29.7 0.00044 20.1 29.7 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFM69730.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KFM69730.1 - 0.029 14.2 5.4 0.021 14.6 3.5 1.8 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Mustang PF15682.5 KFM69730.1 - 0.17 12.0 1.7 1.6 8.9 0.6 2.7 2 0 0 2 2 2 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 CALCOCO1 PF07888.11 KFM69730.1 - 3.3 6.5 39.7 0.31 9.9 25.0 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 KFM69730.1 - 9.9 5.5 41.6 9.2 5.6 16.1 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 SMC_N PF02463.19 KFM69731.1 - 2.5e-06 27.1 14.0 4.8e-06 26.2 14.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF3632 PF12311.8 KFM69731.1 - 0.15 12.5 0.9 0.27 11.7 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) TACC_C PF05010.14 KFM69731.1 - 0.16 11.8 37.6 0.15 11.8 21.5 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal F-actin_cap_A PF01267.17 KFM69731.1 - 0.26 10.7 7.7 0.29 10.5 6.5 1.5 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Lectin_N PF03954.14 KFM69731.1 - 1.9 8.3 8.4 10 5.9 0.9 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Ground-like PF04155.18 KFM69731.1 - 2.6 8.8 6.9 0.71 10.6 2.1 2.6 2 0 0 2 2 2 0 Ground-like domain PDEase_I PF00233.19 KFM69732.1 - 2.7e-25 89.5 0.1 2.9e-25 89.4 0.1 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MFS_1 PF07690.16 KFM69733.1 - 3.2e-05 23.0 0.1 3.4e-05 22.9 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM69733.1 - 0.0036 16.2 4.6 0.0042 16.0 4.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFM69733.1 - 0.011 14.6 0.0 0.011 14.6 0.0 1.0 1 0 0 1 1 1 0 MFS_1 like family MFS_1_like PF12832.7 KFM69734.1 - 9.8e-06 24.7 1.4 1.2e-05 24.4 0.7 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM69734.1 - 1.4e-05 24.3 7.2 1.5e-05 24.1 7.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFM69734.1 - 0.0036 15.9 5.0 0.0036 15.9 5.0 1.5 2 0 0 2 2 2 1 MFS/sugar transport protein OATP PF03137.20 KFM69734.1 - 0.067 11.5 5.5 0.02 13.2 1.4 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SPC12 PF06645.13 KFM69734.1 - 7.2 6.8 8.8 0.34 11.0 2.3 2.2 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.16 KFM69735.1 - 2.1e-15 56.5 10.5 2.7e-15 56.2 10.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AKAP2_C PF15304.6 KFM69737.1 - 6.7e-14 52.0 15.0 1.4e-08 34.5 4.3 7.2 2 2 2 7 7 7 5 A-kinase anchor protein 2 C-terminus RVT_1 PF00078.27 KFM69738.1 - 2.1e-11 43.8 0.0 4.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CX9C PF16860.5 KFM69739.1 - 0.072 13.1 0.5 0.6 10.2 0.0 2.6 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, E3_UbLigase_RBR PF18091.1 KFM69740.1 - 0.14 12.3 2.5 1.4 9.1 0.6 2.4 2 0 0 2 2 2 0 E3 Ubiquitin Ligase RBR C-terminal domain Imm30 PF15565.6 KFM69742.1 - 0.026 14.6 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 30 VHP PF02209.19 KFM69744.1 - 1.3e-16 60.4 1.0 1.9e-16 59.8 1.0 1.3 1 0 0 1 1 1 1 Villin headpiece domain AbLIM_anchor PF16182.5 KFM69744.1 - 0.00027 20.9 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 Putative adherens-junction anchoring region of AbLIM zf-MYND PF01753.18 KFM69746.1 - 8.3e-06 25.8 10.0 8.3e-06 25.8 10.0 2.0 2 0 0 2 2 2 1 MYND finger H2TH PF06831.14 KFM69746.1 - 0.078 13.0 0.1 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain HABP4_PAI-RBP1 PF04774.15 KFM69747.1 - 2.4e-24 86.4 11.2 2.4e-24 86.4 11.2 4.1 3 2 0 3 3 3 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 KFM69747.1 - 7.8e-17 62.4 17.0 7.8e-17 62.4 17.0 2.8 2 1 1 3 3 3 1 Intracellular hyaluronan-binding protein 4 N-terminal DUF3439 PF11921.8 KFM69747.1 - 0.26 11.2 0.7 0.54 10.2 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) IER PF05760.12 KFM69747.1 - 3.7 7.8 7.6 10 6.3 0.6 2.1 2 0 0 2 2 2 0 Immediate early response protein (IER) LRR_8 PF13855.6 KFM69749.1 - 5.2e-37 125.4 56.6 7.5e-13 48.0 4.6 6.2 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFM69749.1 - 1.1e-24 86.8 26.1 1.7e-10 41.0 3.4 3.2 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM69749.1 - 1.6e-16 60.1 41.0 0.00057 20.2 2.1 7.3 3 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM69749.1 - 8.7e-08 31.9 18.2 5.9e-06 25.9 1.5 3.3 1 1 2 3 3 3 3 Leucine-rich repeat ADPrib_exo_Tox PF03496.14 KFM69749.1 - 0.013 14.9 0.8 0.016 14.5 0.2 1.5 2 0 0 2 2 2 0 ADP-ribosyltransferase exoenzyme DDE_3 PF13358.6 KFM69749.1 - 0.013 15.3 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease LRR_1 PF00560.33 KFM69749.1 - 0.11 13.1 31.4 2.9 8.8 0.2 9.6 9 3 1 10 10 10 0 Leucine Rich Repeat LRR_6 PF13516.6 KFM69749.1 - 0.11 12.6 26.8 17 5.8 0.3 9.6 11 0 0 11 11 11 0 Leucine Rich repeat NosD PF05048.13 KFM69749.1 - 0.84 8.9 9.6 0.8 8.9 3.4 2.5 2 1 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Innexin PF00876.18 KFM69751.1 - 9e-24 84.4 0.1 9.1e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 Innexin DUF4674 PF15719.5 KFM69752.1 - 1.6e-13 51.1 10.0 1.6e-13 51.1 10.0 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4674) Rpr2 PF04032.16 KFM69752.1 - 0.00049 20.3 0.8 0.00049 20.3 0.8 2.5 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF5641 PF18701.1 KFM69753.1 - 0.00015 21.9 0.1 0.0002 21.5 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF2464 PF10240.9 KFM69754.1 - 0.01 15.4 0.2 0.14 11.8 0.0 2.0 1 1 0 2 2 2 0 Multivesicular body subunit 12 DENN PF02141.21 KFM69755.1 - 1.1e-13 51.6 0.1 1.4e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFM69755.1 - 8.5e-06 26.4 0.0 1.7e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 uDENN domain DENN PF02141.21 KFM69756.1 - 9e-22 77.9 2.6 1e-21 77.8 2.6 1.0 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KFM69757.1 - 1.6e-09 37.6 2.0 3.5e-09 36.5 2.0 1.6 1 0 0 1 1 1 1 dDENN domain LPD25 PF18840.1 KFM69757.1 - 0.094 13.3 0.2 0.14 12.7 0.2 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 25 APC_u5 PF16630.5 KFM69759.1 - 0.05 14.6 0.5 0.094 13.8 0.4 1.6 1 1 0 1 1 1 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs HSP70 PF00012.20 KFM69761.1 - 1.3e-255 849.2 1.8 1.5e-255 849.0 1.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM69761.1 - 3.3e-16 59.0 0.0 8.6e-15 54.4 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KFM69761.1 - 0.0058 15.9 0.3 0.026 13.8 0.1 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.6 KFM69761.1 - 0.0078 16.6 0.5 9.9 6.6 0.0 3.3 3 1 0 3 3 3 2 Cell division protein FtsA DUF1894 PF08979.11 KFM69761.1 - 0.019 15.3 0.0 24 5.4 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1894) StbA PF06406.11 KFM69761.1 - 0.049 12.9 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 StbA protein FGGY_C PF02782.16 KFM69761.1 - 0.057 13.1 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 KFM69761.1 - 0.1 11.8 5.7 0.18 11.0 5.7 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 TBCA PF02970.16 KFM69761.1 - 4.4 7.7 9.7 2.7 8.4 7.4 1.9 2 0 0 2 2 2 0 Tubulin binding cofactor A HSP70 PF00012.20 KFM69762.1 - 1e-255 849.6 1.9 1.1e-255 849.5 1.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM69762.1 - 3.3e-16 59.0 0.0 8.6e-15 54.4 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KFM69762.1 - 0.006 15.9 0.3 0.026 13.8 0.1 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.6 KFM69762.1 - 0.0076 16.7 0.5 9.9 6.6 0.0 3.3 3 1 0 3 3 3 2 Cell division protein FtsA DUF1894 PF08979.11 KFM69762.1 - 0.019 15.3 0.0 24 5.4 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1894) StbA PF06406.11 KFM69762.1 - 0.037 13.3 0.1 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 StbA protein FGGY_C PF02782.16 KFM69762.1 - 0.058 13.1 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 KFM69762.1 - 0.13 11.5 5.9 0.23 10.7 5.9 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 PIG-S PF10510.9 KFM69763.1 - 1.9e-109 366.8 4.2 2.2e-109 366.6 4.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Acyltransferase PF01553.21 KFM69765.1 - 7.7e-08 32.0 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DHHC PF01529.20 KFM69766.1 - 1.2e-34 119.3 17.4 1.2e-34 119.3 17.4 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase 7TMR-DISM_7TM PF07695.11 KFM69766.1 - 0.0082 16.1 4.6 0.0082 16.1 4.6 2.0 2 0 0 2 2 2 1 7TM diverse intracellular signalling LacY_symp PF01306.19 KFM69766.1 - 0.016 14.0 5.1 0.026 13.3 5.1 1.2 1 0 0 1 1 1 0 LacY proton/sugar symporter ATG22 PF11700.8 KFM69766.1 - 0.1 11.2 1.0 0.18 10.4 1.0 1.3 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF3290 PF11694.8 KFM69766.1 - 9.2 6.2 6.5 20 5.2 6.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Pkinase PF00069.25 KFM69767.1 - 4.8e-71 239.2 0.0 9.3e-71 238.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM69767.1 - 1.8e-41 142.2 0.3 3.3e-41 141.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM69767.1 - 2.8e-09 36.7 0.1 5.9e-08 32.4 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KFM69767.1 - 0.017 14.5 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ge1_WD40 PF16529.5 KFM69768.1 - 5.6e-05 22.3 0.3 5.6e-05 22.3 0.3 1.7 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5345 PF17280.2 KFM69768.1 - 0.059 13.3 0.1 0.25 11.4 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5345) YpjP PF14005.6 KFM69768.1 - 0.1 12.6 1.8 1 9.4 0.3 2.9 1 1 2 3 3 3 0 YpjP-like protein Rnk_N PF14760.6 KFM69768.1 - 0.17 12.4 0.8 7.3 7.2 0.1 2.9 2 0 0 2 2 2 0 Rnk N-terminus partial_CstF PF15861.5 KFM69768.1 - 0.2 11.5 2.1 24 4.8 0.0 2.8 1 1 1 2 2 2 0 Partial cleavage stimulation factor domain baeRF_family12 PF18856.1 KFM69768.1 - 0.22 12.1 2.1 1.8 9.1 0.3 2.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 T5orf172 PF10544.9 KFM69768.1 - 0.38 11.3 1.9 1.6 9.3 0.3 2.8 3 0 0 3 3 3 0 T5orf172 domain OmpH PF03938.14 KFM69768.1 - 6.8 7.0 21.4 6 7.2 7.3 3.1 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-RING_9 PF13901.6 KFM69769.1 - 2e-46 158.6 2.7 2.2e-46 158.4 2.7 1.0 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon DnaJ_CXXCXGXG PF00684.19 KFM69769.1 - 0.37 11.2 12.7 2.5 8.5 6.9 2.6 1 1 1 2 2 2 0 DnaJ central domain zf-RING_2 PF13639.6 KFM69769.1 - 0.98 9.8 13.7 0.12 12.8 8.7 2.0 1 1 1 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.6 KFM69769.1 - 5.4 7.0 13.9 33 4.5 13.9 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PhnA_Zn_Ribbon PF08274.12 KFM69769.1 - 5.7 7.0 9.7 21 5.2 3.3 3.2 2 1 0 2 2 2 0 PhnA Zinc-Ribbon HTH_Tnp_Tc3_2 PF01498.18 KFM69770.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69770.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM69772.1 - 9.8e-11 41.6 0.0 1.1e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Homeodomain PF00046.29 KFM69773.1 - 3.3e-20 71.7 7.1 5.6e-20 70.9 7.1 1.4 1 0 0 1 1 1 1 Homeodomain Abdominal-A PF12407.8 KFM69773.1 - 1.8e-08 33.7 1.8 4.5e-08 32.5 1.8 1.6 1 0 0 1 1 1 1 Homeobox protein DUF2870 PF11069.8 KFM69773.1 - 0.13 12.6 2.1 0.24 11.8 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Homeobox_KN PF05920.11 KFM69773.1 - 0.15 12.0 0.5 0.43 10.5 0.5 1.8 1 0 0 1 1 1 0 Homeobox KN domain Stn1 PF10451.9 KFM69773.1 - 0.26 10.2 1.8 0.38 9.7 1.8 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 HTH_Tnp_Tc3_2 PF01498.18 KFM69774.1 - 7.6e-17 61.3 2.1 5.6e-16 58.5 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69774.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69774.1 - 6.7e-07 29.0 0.5 3.4e-06 26.7 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69774.1 - 0.011 15.5 0.3 0.033 14.0 0.3 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM69774.1 - 8 7.2 14.4 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM69775.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69775.1 - 2e-13 50.3 0.0 3.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DAN PF03045.15 KFM69776.1 - 2.2e-06 27.7 1.8 2.6e-06 27.4 1.8 1.1 1 0 0 1 1 1 1 DAN domain Ion_trans_2 PF07885.16 KFM69778.1 - 0.0055 16.6 0.4 0.086 12.8 0.2 2.1 2 0 0 2 2 2 2 Ion channel DUF4590 PF15257.6 KFM69779.1 - 5e-33 113.4 0.2 1.1e-32 112.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) Mito_carr PF00153.27 KFM69780.1 - 2.1e-24 85.3 1.0 2.7e-22 78.5 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein LRR_8 PF13855.6 KFM69782.1 - 2.2e-07 30.5 0.2 3.5e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KFM69782.1 - 6.2e-07 29.6 0.2 9.4e-07 29.1 0.2 1.4 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM69782.1 - 0.00098 19.4 0.6 0.58 10.9 0.1 2.6 2 1 0 2 2 2 2 Leucine Rich Repeat LRR_6 PF13516.6 KFM69782.1 - 0.0012 18.7 0.2 1.6 9.0 0.1 2.4 2 0 0 2 2 2 2 Leucine Rich repeat Suppressor_P21 PF11479.8 KFM69782.1 - 0.008 16.3 0.1 0.017 15.3 0.1 1.6 1 1 0 1 1 1 1 RNA silencing suppressor P21 C-terminal domain LRR_8 PF13855.6 KFM69783.1 - 1.1e-23 82.7 2.5 3e-12 46.1 0.3 4.5 4 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFM69783.1 - 6.2e-13 48.7 3.6 1.2e-06 28.7 0.5 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM69783.1 - 7.2e-12 45.4 1.2 1.2e-07 31.7 0.0 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM69783.1 - 1.8e-05 24.3 0.7 0.0036 16.8 0.1 2.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KFM69783.1 - 0.0011 18.9 0.8 8.3 6.8 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 KFM69783.1 - 0.0013 19.0 4.9 1.4 9.7 0.0 5.1 5 2 0 5 5 5 1 Leucine Rich Repeat DUF4052 PF13261.6 KFM69783.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4052) Transposase_1 PF01359.18 KFM69784.1 - 0.0062 16.3 0.1 0.0079 16.0 0.1 1.1 1 0 0 1 1 1 1 Transposase (partial DDE domain) DUF769 PF05590.11 KFM69784.1 - 0.093 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) LRR_8 PF13855.6 KFM69785.1 - 2.6e-16 59.1 0.8 5.1e-08 32.5 0.2 3.6 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM69785.1 - 5.3e-13 48.9 4.0 1.4e-06 28.5 0.3 4.0 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM69785.1 - 6.2e-08 32.7 0.5 2.1e-06 27.7 0.0 2.6 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM69785.1 - 0.00059 20.0 0.6 3.5 8.5 0.0 5.6 5 2 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 KFM69785.1 - 0.0008 18.9 0.0 0.019 14.5 0.0 2.2 1 1 0 2 2 2 1 Leucine-rich repeat SH3_1 PF00018.28 KFM69786.1 - 4.4e-08 32.6 0.0 7.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM69786.1 - 7.2e-07 29.0 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM69786.1 - 0.00025 20.7 0.0 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFM69786.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Rit1_C PF17184.4 KFM69786.1 - 0.038 13.4 0.1 0.04 13.4 0.1 1.1 1 0 0 1 1 1 0 Rit1 N-terminal domain SH3_16 PF18348.1 KFM69786.1 - 0.049 13.4 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain RhoGEF PF00621.20 KFM69787.1 - 9.4e-42 143.3 2.9 3.2e-41 141.6 2.2 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFM69787.1 - 2.2e-06 28.1 0.1 7.2e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_10 PF15411.6 KFM69787.1 - 7.5e-05 23.0 1.0 0.00025 21.3 0.0 2.3 2 1 1 3 3 3 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFM69787.1 - 0.015 15.3 0.0 0.067 13.2 0.0 2.0 2 0 0 2 2 2 0 PH domain Neur_chan_memb PF02932.16 KFM69790.1 - 6.7e-16 59.1 0.3 2.5e-13 50.7 1.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region E1-E2_ATPase PF00122.20 KFM69790.1 - 0.56 9.7 2.0 0.66 9.5 0.0 1.9 2 1 0 2 2 2 0 E1-E2 ATPase Neur_chan_LBD PF02931.23 KFM69791.1 - 6.6e-22 78.0 0.1 7.9e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain RhoGAP PF00620.27 KFM69793.1 - 3.2e-41 140.7 0.0 1.4e-40 138.6 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain PDZ PF00595.24 KFM69793.1 - 4e-09 36.7 0.0 8.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain C2 PF00168.30 KFM69793.1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 C2 domain PDZ_6 PF17820.1 KFM69793.1 - 0.019 14.8 1.1 0.14 12.0 0.2 2.5 1 1 1 2 2 2 0 PDZ domain Tetraspanin PF00335.20 KFM69794.1 - 5.6e-40 137.5 8.0 6.4e-40 137.3 8.0 1.0 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.23 KFM69794.1 - 0.013 15.6 1.2 0.013 15.6 1.2 1.8 2 0 0 2 2 2 0 Membrane-associating domain DUF2650 PF10853.8 KFM69794.1 - 0.07 12.9 1.2 0.07 12.9 1.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2650) DUF411 PF04214.13 KFM69794.1 - 0.16 11.9 0.0 25 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF ETRAMP PF09716.10 KFM69794.1 - 0.98 9.5 6.7 2.4 8.3 0.0 3.3 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) SUR7 PF06687.12 KFM69794.1 - 3.1 7.4 10.8 0.43 10.2 6.0 1.9 2 0 0 2 2 2 0 SUR7/PalI family PrgI PF12666.7 KFM69794.1 - 9.1 7.1 12.1 0.46 11.2 1.3 2.9 3 0 0 3 3 3 0 PrgI family protein HTH_Tnp_Tc3_2 PF01498.18 KFM69795.1 - 5.1e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69795.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69795.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69795.1 - 0.0027 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69795.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RVT_1 PF00078.27 KFM69796.1 - 7.3e-13 48.5 0.3 8.5e-13 48.3 0.3 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TEX15 PF15326.6 KFM69796.1 - 0.022 14.5 0.1 0.026 14.2 0.1 1.1 1 0 0 1 1 1 0 Testis expressed sequence 15 AMP-binding PF00501.28 KFM69798.1 - 6.7e-48 163.3 0.0 9.8e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM69798.1 - 2.5e-07 30.5 8.1 5.4e-07 29.4 8.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DDE_3 PF13358.6 KFM69799.1 - 2.7e-16 59.7 0.1 2.9e-15 56.3 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69799.1 - 1.3e-10 41.4 1.0 2.7e-10 40.4 1.0 1.6 1 0 0 1 1 1 1 Transposase Cpn60_TCP1 PF00118.24 KFM69800.1 - 0.0015 17.3 0.0 0.0018 17.0 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAPS_reduct PF01507.19 KFM69801.1 - 6.6e-32 110.9 0.1 6.7e-21 75.1 0.0 2.5 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 KFM69801.1 - 3.6e-30 104.5 0.0 6.3e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF4371 PF14291.6 KFM69802.1 - 7.4e-10 38.9 0.2 1.2e-09 38.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM69802.1 - 7.1e-06 25.7 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2_12 PF18658.1 KFM69802.1 - 0.005 16.4 0.5 0.013 15.0 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger C2H2-type BORCS6 PF10157.9 KFM69802.1 - 0.11 12.7 0.1 0.27 11.5 0.1 1.6 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 Pkinase PF00069.25 KFM69803.1 - 9.2e-76 254.7 0.1 1.1e-75 254.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM69803.1 - 7.1e-47 159.9 0.0 9e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM69803.1 - 2.6e-06 27.0 0.0 8.2e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFM69803.1 - 0.00093 18.6 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Spindle_Spc25 PF08234.12 KFM69804.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 Pkinase_Tyr PF07714.17 KFM69805.1 - 1.9e-91 305.9 0.0 2.6e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM69805.1 - 8.5e-41 140.1 0.0 1.3e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 KFM69805.1 - 1.2e-23 83.2 2.7 2.9e-23 82.0 2.7 1.7 1 0 0 1 1 1 1 Kringle domain Fz PF01392.22 KFM69805.1 - 4.5e-11 43.3 1.4 1.1e-10 42.1 1.4 1.7 1 0 0 1 1 1 1 Fz domain Ig_3 PF13927.6 KFM69805.1 - 4.9e-09 36.7 0.5 1.1e-08 35.5 0.2 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM69805.1 - 9.7e-09 35.5 0.2 3.4e-08 33.7 0.2 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM69805.1 - 3.6e-07 30.2 0.0 9.9e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFM69805.1 - 8.8e-06 25.7 0.1 2.5e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFM69805.1 - 0.00042 20.4 0.7 0.00094 19.3 0.7 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Haspin_kinase PF12330.8 KFM69805.1 - 0.057 12.4 0.1 0.4 9.6 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain HTH_Tnp_Tc3_2 PF01498.18 KFM69806.1 - 4.2e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69806.1 - 1.1e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69806.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69806.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69806.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ANAPC10 PF03256.16 KFM69807.1 - 1.3e-61 207.4 0.1 1.5e-61 207.3 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KFM69807.1 - 0.00013 22.1 0.1 0.0002 21.5 0.1 1.3 1 1 0 1 1 1 1 F5/8 type C domain SH3_2 PF07653.17 KFM69808.1 - 0.00082 19.0 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Amelogenin PF02948.15 KFM69808.1 - 0.003 18.2 2.1 0.003 18.2 2.1 1.5 2 0 0 2 2 2 1 Amelogenin SH3_1 PF00018.28 KFM69808.1 - 0.18 11.4 1.9 1.1 9.0 0.1 2.9 3 1 0 3 3 3 0 SH3 domain CAF1A PF12253.8 KFM69809.1 - 2e-23 82.4 5.5 2e-23 82.4 5.5 5.6 6 1 1 7 7 7 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 KFM69809.1 - 0.0025 17.5 84.8 0.0025 17.5 84.8 5.5 4 2 2 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2345 PF10106.9 KFM69811.1 - 0.0041 17.0 0.0 55 3.6 0.0 6.9 6 1 1 7 7 7 1 Uncharacterized protein conserved in bacteria (DUF2345) Nramp PF01566.18 KFM69813.1 - 6.9e-104 347.7 7.3 8.2e-104 347.4 7.3 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein HTH_Tnp_Tc3_2 PF01498.18 KFM69814.1 - 5.2e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69814.1 - 5.1e-14 52.3 0.0 9.2e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69814.1 - 5.1e-08 32.5 0.8 7.3e-07 28.9 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69814.1 - 0.0024 17.6 0.6 0.0078 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69814.1 - 0.026 14.6 0.4 0.093 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM69814.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF5090 PF17009.5 KFM69815.1 - 2.4 8.1 15.0 5 7.0 15.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Granulin PF00396.18 KFM69816.1 - 0.062 13.6 55.7 0.32 11.4 6.2 5.0 2 2 3 5 5 5 0 Granulin Chitin_bind_4 PF00379.23 KFM69817.1 - 4.6e-12 46.3 10.2 4.6e-12 46.3 10.2 2.4 3 0 0 3 3 3 1 Insect cuticle protein DUF1759 PF03564.15 KFM69819.1 - 0.0036 17.3 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF4817 PF16087.5 KFM69819.1 - 0.013 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) EGF PF00008.27 KFM69821.1 - 7.2e-05 23.0 16.7 0.00045 20.4 9.1 6.2 6 3 0 6 6 6 3 EGF-like domain EGF_2 PF07974.13 KFM69821.1 - 0.0087 16.4 8.9 0.0087 16.4 8.9 5.8 4 1 0 5 5 5 3 EGF-like domain hEGF PF12661.7 KFM69821.1 - 0.034 14.8 2.1 0.034 14.8 2.1 6.6 6 0 0 6 6 6 0 Human growth factor-like EGF EB PF01683.18 KFM69821.1 - 9 6.7 52.8 0.092 13.0 4.1 4.9 3 2 1 4 4 4 0 EB module CBM_14 PF01607.24 KFM69822.1 - 6.1e-11 42.3 7.3 9.5e-11 41.7 7.3 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain HTH_Tnp_Tc3_2 PF01498.18 KFM69823.1 - 4.8e-16 58.8 0.5 1.1e-15 57.6 0.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69823.1 - 1.3e-06 28.9 2.7 1.3e-05 25.7 0.3 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM69823.1 - 0.0046 16.9 0.9 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_26 PF13443.6 KFM69823.1 - 0.021 15.3 0.4 4.2 7.9 0.2 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 KFM69823.1 - 0.026 14.6 0.4 0.82 9.8 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix MarR_2 PF12802.7 KFM69823.1 - 0.059 13.3 0.4 1.3 9.0 0.0 2.6 2 1 1 3 3 3 0 MarR family HTH_33 PF13592.6 KFM69823.1 - 0.12 12.0 0.1 0.12 12.0 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM69824.1 - 2.1e-16 59.9 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69824.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PTS_IIA PF02255.16 KFM69826.1 - 0.038 14.0 0.6 0.062 13.3 0.6 1.4 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Laminin_G_2 PF02210.24 KFM69827.1 - 1.2e-62 210.0 3.6 1.9e-21 76.9 0.0 4.3 4 0 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.23 KFM69827.1 - 1.4e-43 148.3 0.1 9e-19 68.0 0.0 4.8 4 1 0 4 4 4 4 Laminin G domain Laminin_G_3 PF13385.6 KFM69827.1 - 7.1e-13 49.0 1.5 0.0024 18.0 0.0 4.3 4 0 0 4 4 4 4 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFM69827.1 - 1.9e-05 24.9 27.4 0.0086 16.4 10.7 3.1 2 0 0 2 2 2 2 EGF-like domain Fibrinogen_C PF00147.18 KFM69827.1 - 0.056 13.2 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Laminin_G_2 PF02210.24 KFM69828.1 - 8e-21 74.9 1.0 1.5e-12 48.2 0.4 2.4 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFM69828.1 - 7.1e-14 52.1 0.1 2.4e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFM69828.1 - 7.8e-12 45.3 18.5 3.6e-07 30.4 5.5 2.5 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFM69828.1 - 0.0075 16.9 1.9 0.0075 16.9 1.9 2.7 2 0 0 2 2 2 1 Human growth factor-like EGF m04gp34like PF12216.8 KFM69828.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Immune evasion protein BicD PF09730.9 KFM69829.1 - 6.7e-215 715.8 73.0 6.7e-215 715.8 73.0 1.6 2 0 0 2 2 2 1 Microtubule-associated protein Bicaudal-D CENP-F_leu_zip PF10473.9 KFM69829.1 - 0.003 17.6 5.4 0.003 17.6 5.4 8.1 4 2 3 7 7 7 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFM69829.1 - 0.96 8.3 102.4 0.1 11.4 6.3 6.1 4 2 2 6 6 6 0 Spc7 kinetochore protein DUF1759 PF03564.15 KFM69829.1 - 6.1 6.8 20.5 0.071 13.0 5.1 4.4 3 1 0 4 4 4 0 Protein of unknown function (DUF1759) Mce4_CUP1 PF11887.8 KFM69829.1 - 7 6.0 14.2 2.9 7.3 0.7 3.6 3 1 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative Exo_endo_phos_2 PF14529.6 KFM69830.1 - 1.2e-23 83.2 5.3 1.2e-23 83.2 5.3 2.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM69830.1 - 0.0014 18.2 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_Tnp_Tc3_2 PF01498.18 KFM69831.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69831.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69831.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69831.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69831.1 - 1.8 9.2 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain GDI PF00996.18 KFM69832.1 - 1e-231 769.0 0.1 1.2e-231 768.8 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SH3_14 PF18343.1 KFM69832.1 - 0.0089 16.1 0.1 7.3 6.7 0.0 2.6 2 0 0 2 2 2 2 Dda helicase SH3 domain CECR6_TMEM121 PF14997.6 KFM69833.1 - 1.8e-50 171.5 11.2 2.9e-50 170.8 11.2 1.3 1 0 0 1 1 1 1 CECR6/TMEM121 family ECF_trnsprt PF12822.7 KFM69833.1 - 0.00044 20.4 0.5 0.00044 20.4 0.5 2.0 2 1 0 2 2 2 1 ECF transporter, substrate-specific component VKOR PF07884.14 KFM69833.1 - 0.032 14.4 0.7 0.032 14.4 0.7 2.6 2 1 0 2 2 2 0 Vitamin K epoxide reductase family Noggin PF05806.12 KFM69834.1 - 6e-69 232.2 6.5 7e-69 232.0 6.5 1.0 1 0 0 1 1 1 1 Noggin Noggin PF05806.12 KFM69835.1 - 1.3e-35 123.3 3.5 1.9e-35 122.8 3.5 1.2 1 0 0 1 1 1 1 Noggin GDPD PF03009.17 KFM69836.1 - 0.00024 20.9 0.0 0.00028 20.7 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DDE_3 PF13358.6 KFM69837.1 - 9.4e-10 38.4 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69837.1 - 9.3e-09 35.4 0.2 1.9e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 Transposase 7tm_1 PF00001.21 KFM69838.1 - 6.2e-53 179.8 17.5 8.1e-53 179.4 17.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM69838.1 - 8.2e-19 68.0 19.7 1.1e-18 67.6 19.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM69838.1 - 1.1e-09 38.4 23.1 1.7e-09 37.7 23.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFM69838.1 - 0.014 15.2 8.7 0.025 14.3 8.7 1.4 1 0 0 1 1 1 0 Olfactory receptor UPF0542 PF15086.6 KFM69838.1 - 0.24 11.4 1.5 1.2 9.2 1.5 2.2 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 Asp4 PF16996.5 KFM69838.1 - 8.3 6.3 6.4 1.1 9.1 0.1 2.7 3 0 0 3 3 3 0 Accessory secretory protein Sec Asp4 DAO PF01266.24 KFM69840.1 - 8.5e-26 91.4 0.0 9.9e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM69840.1 - 3.8e-05 23.1 0.0 0.062 12.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM69840.1 - 0.0023 16.7 0.0 0.26 10.0 0.0 2.1 1 1 1 2 2 2 2 HI0933-like protein Phi-29_GP3 PF05435.11 KFM69840.1 - 0.019 14.5 0.1 0.025 14.1 0.1 1.1 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 Amino_oxidase PF01593.24 KFM69840.1 - 0.04 13.2 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM69840.1 - 0.075 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HBD PF18534.1 KFM69840.1 - 0.082 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Helical bundle domain NAD_binding_9 PF13454.6 KFM69840.1 - 0.092 12.7 0.5 2.1 8.3 0.5 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KFM69840.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KFM69841.1 - 9.9e-07 28.6 0.0 1.1e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KFM69842.1 - 3.1e-07 30.3 0.0 3.3e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Myb_DNA-bind_6 PF13921.6 KFM69843.1 - 6.9e-07 29.4 1.8 7.1e-05 23.0 0.1 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFM69843.1 - 0.0005 20.2 0.4 0.074 13.3 0.1 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain COG5 PF10392.9 KFM69843.1 - 0.57 10.4 4.7 0.15 12.2 0.7 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Transposase_22 PF02994.14 KFM69843.1 - 0.61 10.3 4.7 2.2 8.5 0.4 3.0 3 1 0 3 3 3 0 L1 transposable element RBD-like domain Glyco_hydro_18 PF00704.28 KFM69844.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 SAS4 PF15460.6 KFM69844.1 - 0.12 12.5 0.6 0.64 10.1 0.0 2.5 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 HTH_Tnp_Tc3_2 PF01498.18 KFM69846.1 - 7.2e-10 39.0 0.1 1.5e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69846.1 - 2.6e-09 37.0 0.0 3.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Trypsin PF00089.26 KFM69848.1 - 8.7e-66 221.9 0.3 2e-65 220.7 0.0 1.8 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 KFM69848.1 - 1.1e-07 32.2 0.0 2.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFM69848.1 - 4.8e-05 24.3 0.1 0.00012 23.0 0.1 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF4490 PF14892.6 KFM69849.1 - 1.4e-23 82.9 4.6 8.4e-21 74.0 1.6 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4490) CAV_VP3 PF04771.12 KFM69849.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein HTH_Tnp_Tc3_2 PF01498.18 KFM69852.1 - 8.1e-16 58.0 6.5 1.5e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69852.1 - 8.6e-16 58.0 0.1 8.7e-15 54.7 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM69852.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69852.1 - 0.0028 17.4 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69852.1 - 0.016 15.3 0.1 0.068 13.3 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69852.1 - 0.036 14.1 2.6 0.037 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix OATP PF03137.20 KFM69853.1 - 8.1e-36 123.4 1.6 9.3e-36 123.2 1.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFM69853.1 - 0.0015 17.5 2.5 0.0038 16.2 3.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KFM69854.1 - 1.8e-14 53.0 0.1 2e-14 52.8 0.1 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family HTH_Tnp_Tc3_2 PF01498.18 KFM69855.1 - 2.1e-16 59.9 2.2 3.6e-16 59.2 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69855.1 - 2.6e-13 50.0 0.0 4.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SWIM PF04434.17 KFM69856.1 - 0.044 13.5 0.1 0.092 12.4 0.1 1.5 1 0 0 1 1 1 0 SWIM zinc finger CSD2 PF17876.1 KFM69857.1 - 0.09 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Cold shock domain RRM_1 PF00076.22 KFM69858.1 - 4.8e-21 74.4 0.1 8.1e-21 73.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM69858.1 - 1.2e-05 24.9 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM69858.1 - 2.3e-05 24.1 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif SET_assoc PF11767.8 KFM69858.1 - 0.00086 18.9 0.0 0.0032 17.1 0.0 2.1 1 1 0 1 1 1 1 Histone lysine methyltransferase SET associated zf-CCHC PF00098.23 KFM69858.1 - 0.0011 18.9 1.9 0.0021 18.1 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KFM69858.1 - 0.0045 16.9 1.4 0.0091 15.9 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KFM69858.1 - 0.01 15.6 1.6 0.028 14.2 1.0 2.1 2 0 0 2 2 2 0 Zinc knuckle RRM_7 PF16367.5 KFM69858.1 - 0.014 15.5 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Limkain-b1 PF11608.8 KFM69858.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 RRM_8 PF11835.8 KFM69858.1 - 0.05 13.8 0.0 0.072 13.3 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain HTH_27 PF13463.6 KFM69858.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain MutS_II PF05188.17 KFM69858.1 - 0.057 13.7 0.5 0.3 11.4 0.1 2.0 2 0 0 2 2 2 0 MutS domain II RRM_Rrp7 PF17799.1 KFM69858.1 - 0.11 12.2 1.6 1.3 8.8 0.1 2.6 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain NADH_oxidored PF08040.11 KFM69858.1 - 0.12 12.0 0.0 0.41 10.4 0.0 1.9 1 0 0 1 1 1 0 MNLL subunit HD PF01966.22 KFM69858.1 - 0.27 11.5 1.2 0.49 10.6 1.2 1.3 1 0 0 1 1 1 0 HD domain TMEM237 PF15383.6 KFM69859.1 - 2.2e-11 43.3 0.0 2.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 237 PDZ_6 PF17820.1 KFM69861.1 - 3.7e-14 52.3 0.0 8.2e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM69861.1 - 1.4e-10 41.3 0.0 4e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM69861.1 - 1.1e-07 32.0 0.0 2.1e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 KFM69861.1 - 0.012 15.9 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain PUFD PF16553.5 KFM69861.1 - 0.042 14.0 0.3 0.098 12.8 0.3 1.6 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain Tricorn_PDZ PF14685.6 KFM69861.1 - 0.18 11.8 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain DDE_1 PF03184.19 KFM69863.1 - 4e-11 42.9 0.1 5.2e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease EntA_Immun PF08951.10 KFM69863.1 - 0.019 15.3 0.1 0.03 14.7 0.1 1.3 1 0 0 1 1 1 0 Enterocin A Immunity HSP20 PF00011.21 KFM69864.1 - 1e-18 67.3 0.0 2.8e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Hsp20/alpha crystallin family SKA1 PF07160.12 KFM69864.1 - 0.025 14.4 0.7 0.034 14.0 0.7 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 ADIP PF11559.8 KFM69864.1 - 0.04 14.0 0.6 0.065 13.3 0.1 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GPS2_interact PF15784.5 KFM69864.1 - 0.089 13.2 2.0 0.13 12.7 1.2 1.7 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Trimer_CC PF08954.11 KFM69864.1 - 0.13 11.9 1.2 0.29 10.7 1.2 1.6 1 0 0 1 1 1 0 Trimerisation motif ArsA_HSP20 PF17886.1 KFM69864.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Methyltransf_5 PF01795.19 KFM69865.1 - 6e-82 275.6 0.0 9.9e-82 274.9 0.0 1.3 1 1 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 KFM69865.1 - 0.0016 19.1 0.0 0.092 13.5 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFM69865.1 - 0.0029 17.3 0.0 0.0069 16.0 0.0 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 KFM69865.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TMEM117 PF15113.6 KFM69866.1 - 7.8e-55 186.5 10.7 8.7e-55 186.3 10.7 1.0 1 0 0 1 1 1 1 TMEM117 protein family TMEM117 PF15113.6 KFM69867.1 - 4.9e-44 150.9 0.4 6.8e-44 150.4 0.4 1.2 1 0 0 1 1 1 1 TMEM117 protein family COPIIcoated_ERV PF07970.12 KFM69868.1 - 1e-44 153.1 1.0 1.1e-44 152.9 0.2 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFM69868.1 - 4.4e-27 94.3 0.3 8.3e-27 93.4 0.3 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PdxJ PF03740.13 KFM69869.1 - 0.012 14.7 1.8 0.014 14.5 0.1 1.9 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ HTH_Tnp_Tc3_2 PF01498.18 KFM69870.1 - 2.5e-16 59.7 2.2 5e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69870.1 - 6.8e-13 48.6 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69871.1 - 2.3e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69871.1 - 9.6e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM69872.1 - 1.8e-67 220.9 67.1 1.1e-08 35.1 0.4 11.1 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69872.1 - 3.2e-54 178.5 75.3 2.9e-07 30.6 0.8 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69872.1 - 2.1e-42 140.1 70.9 0.00024 21.7 0.2 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM69872.1 - 4e-20 71.5 65.2 0.00046 20.5 1.5 10.3 10 0 0 10 10 10 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM69872.1 - 2.3e-19 69.1 46.6 0.022 15.0 0.1 10.0 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 KFM69872.1 - 1e-15 57.0 40.4 0.15 11.6 0.2 10.0 2 2 8 10 10 10 8 MYST family zinc finger domain zf-C2H2_6 PF13912.6 KFM69872.1 - 1.1e-12 47.6 64.9 0.0021 18.0 0.6 10.4 10 0 0 10 10 10 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM69872.1 - 4.5e-11 42.3 56.4 0.051 13.3 0.5 10.8 10 1 0 10 10 10 7 C2H2-type zinc-finger domain BolA PF01722.18 KFM69872.1 - 1.9e-10 40.9 9.6 0.079 13.3 0.3 6.7 3 2 2 5 5 5 3 BolA-like protein zf-Di19 PF05605.12 KFM69872.1 - 1.6e-07 31.5 45.9 0.13 12.5 3.8 7.2 3 2 3 6 6 6 5 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KFM69872.1 - 8.9e-07 28.8 53.2 0.037 14.0 0.9 9.0 2 1 6 8 8 8 4 BED zinc finger Tox-HNH-HHH PF15637.6 KFM69872.1 - 1.3e-06 28.5 1.2 0.021 14.9 0.0 4.4 1 1 5 6 6 6 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_2 PF12756.7 KFM69872.1 - 5.7e-06 26.6 54.7 0.79 10.1 1.0 9.9 1 1 9 10 10 10 3 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFM69872.1 - 6.9e-05 22.6 18.3 4.6 7.1 0.1 7.7 3 3 5 8 8 8 1 GAGA factor Zn_ribbon_SprT PF17283.2 KFM69872.1 - 7.4e-05 22.6 33.5 0.0093 15.9 1.7 7.5 4 3 5 9 9 9 3 SprT-like zinc ribbon domain DUF4825 PF16107.5 KFM69872.1 - 9e-05 22.5 0.1 9.9 6.4 0.0 4.7 2 2 2 4 4 4 0 Domain of unknown function (DUF4825) zf_UBZ PF18439.1 KFM69872.1 - 0.00021 20.8 40.2 0.34 10.5 0.4 9.4 10 0 0 10 10 10 3 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KFM69872.1 - 0.00074 19.5 32.6 1.8e+04 -17.0 32.6 5.7 1 1 0 1 1 0 0 Double zinc ribbon zf-DBF PF07535.12 KFM69872.1 - 0.0035 17.4 30.5 10 6.3 0.0 8.2 8 0 0 8 8 8 0 DBF zinc finger zf-Sec23_Sec24 PF04810.15 KFM69872.1 - 0.0035 17.3 28.7 7.6 6.7 0.1 9.4 9 1 1 10 10 10 0 Sec23/Sec24 zinc finger DUF2256 PF10013.9 KFM69872.1 - 0.0049 17.0 37.8 5.6 7.2 0.2 9.7 10 0 0 10 10 10 1 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFM69872.1 - 0.008 16.9 40.5 0.15 12.8 2.8 5.4 1 1 3 6 6 6 4 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM69872.1 - 0.01 15.7 33.2 3.7 7.5 0.2 9.1 5 3 5 10 10 10 0 C2H2 type zinc-finger (1 copy) NusB PF01029.18 KFM69872.1 - 0.023 14.9 0.3 33 4.7 0.1 3.6 2 1 2 4 4 4 0 NusB family Zn-ribbon_8 PF09723.10 KFM69872.1 - 0.084 13.0 38.8 2.2 8.5 0.7 7.1 4 3 4 8 8 8 0 Zinc ribbon domain Zf_RING PF16744.5 KFM69872.1 - 0.17 12.0 43.1 7.4 6.8 0.2 9.3 1 1 6 8 8 8 0 KIAA1045 RING finger zf-C2HC_2 PF13913.6 KFM69872.1 - 1.2 9.1 0.0 1.2 9.1 0.0 7.9 8 0 0 8 8 8 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 KFM69872.1 - 2 9.0 42.7 3.4 8.2 0.8 8.8 9 0 0 9 9 9 0 Autophagy receptor zinc finger-C2H2 domain UPF0728 PF15092.6 KFM69872.1 - 2.7 7.9 7.6 13 5.7 0.0 4.3 4 1 0 5 5 4 0 Uncharacterised protein family UPF0728 zf-RRPl_C4 PF17026.5 KFM69872.1 - 5.9 7.0 40.2 2.5 8.2 6.1 4.4 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Guanylate_cyc PF00211.20 KFM69873.1 - 6.8e-16 58.4 0.0 9.1e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFM69874.1 - 1.6e-09 37.4 1.0 1.7e-09 37.3 1.0 1.0 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region HNOBA PF07701.14 KFM69874.1 - 0.034 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Heme NO binding associated DUF2642 PF10842.8 KFM69874.1 - 0.1 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) RNase_H PF00075.24 KFM69878.1 - 1.4e-05 25.3 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNase H Ribosomal_L19e PF01280.20 KFM69879.1 - 0.1 12.7 0.6 0.12 12.5 0.6 1.1 1 0 0 1 1 1 0 Ribosomal protein L19e Ank_2 PF12796.7 KFM69880.1 - 9.3e-20 71.0 0.0 3.7e-10 40.2 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM69880.1 - 4.6e-19 68.5 0.3 0.00016 22.2 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM69880.1 - 4.2e-16 58.8 0.0 1.5e-07 31.5 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM69880.1 - 8e-16 56.5 0.2 0.022 15.3 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KFM69880.1 - 2.1e-15 56.3 0.3 0.0002 21.7 0.0 5.4 5 1 0 5 5 5 4 Ankyrin repeat DNA_binding_1 PF01035.20 KFM69881.1 - 1.7e-27 95.4 0.0 2.9e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SNAPc19 PF15497.6 KFM69883.1 - 0.0069 16.8 2.1 0.0073 16.7 2.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 FlaC_arch PF05377.11 KFM69883.1 - 0.12 12.8 1.1 0.16 12.4 1.1 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CREPT PF16566.5 KFM69884.1 - 1.4e-25 90.2 0.1 1.5e-25 90.1 0.1 1.0 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour YscO-like PF16789.5 KFM69884.1 - 0.0018 18.3 2.0 0.0022 18.0 2.0 1.0 1 0 0 1 1 1 1 YscO-like protein Takusan PF04822.13 KFM69884.1 - 0.0026 17.6 0.8 0.0033 17.3 0.8 1.1 1 0 0 1 1 1 1 Takusan Uds1 PF15456.6 KFM69884.1 - 0.012 15.8 1.5 0.014 15.6 1.5 1.0 1 0 0 1 1 1 0 Up-regulated During Septation Sulfatase_C PF14707.6 KFM69884.1 - 0.14 12.9 0.1 0.15 12.8 0.1 1.0 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase CREPT PF16566.5 KFM69885.1 - 1.7e-27 96.4 1.8 1.8e-27 96.3 1.8 1.0 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 KFM69886.1 - 4.1e-13 49.9 0.1 4.1e-13 49.9 0.1 1.9 2 1 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 KFM69886.1 - 6.1e-07 29.5 0.4 7.8e-07 29.1 0.4 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Sod_Fe_N PF00081.22 KFM69886.1 - 0.031 14.7 1.3 0.055 14.0 1.1 1.5 1 1 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Sipho_Gp37 PF14594.6 KFM69886.1 - 0.16 10.9 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein COX4 PF02936.14 KFM69887.1 - 2.9e-51 173.1 0.0 3.5e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV SNF PF00209.18 KFM69889.1 - 2.7e-10 39.5 2.2 3.1e-10 39.4 2.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF1206 PF06724.11 KFM69889.1 - 0.019 15.1 0.2 0.024 14.7 0.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) SNF PF00209.18 KFM69890.1 - 5.4e-56 190.4 0.1 6e-56 190.2 0.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFM69891.1 - 1.1e-64 219.0 5.7 1.5e-64 218.6 5.7 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family fn3 PF00041.21 KFM69893.1 - 6.1e-15 55.3 0.2 1.8e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III domain fn3_2 PF16893.5 KFM69893.1 - 2.5e-05 24.3 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain fn3_4 PF16794.5 KFM69893.1 - 0.036 14.0 0.0 0.27 11.2 0.0 2.0 1 1 0 1 1 1 0 Fibronectin-III type domain DUF4998 PF16389.5 KFM69893.1 - 0.04 13.5 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function Insulin_TMD PF17870.1 KFM69894.1 - 0.016 15.3 2.4 0.03 14.4 2.4 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Sclerostin PF05463.11 KFM69894.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Sclerostin (SOST) Dscam_C PF12355.8 KFM69895.1 - 0.07 14.1 0.1 0.071 14.1 0.1 1.1 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Na_Ca_ex PF01699.24 KFM69896.1 - 8.4e-51 171.9 39.1 6.5e-26 91.1 16.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 KFM69896.1 - 3.3e-45 152.4 2.5 5.1e-22 77.9 0.2 2.8 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex_C PF16494.5 KFM69896.1 - 3.2e-05 24.4 0.1 6.8e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain DUF4843 PF16132.5 KFM69896.1 - 0.033 13.7 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4843) Hex_IIIa PF02455.16 KFM69896.1 - 0.087 11.6 0.0 0.34 9.6 0.0 1.9 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) adh_short PF00106.25 KFM69898.1 - 2.6e-52 177.1 0.5 2.9e-52 177.0 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM69898.1 - 2.7e-44 151.5 0.1 3.1e-44 151.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM69898.1 - 3.7e-15 56.3 0.3 4.8e-15 55.9 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM69898.1 - 9.6e-07 28.5 0.2 1.9e-06 27.5 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFM69898.1 - 2.3e-06 27.6 0.4 2.7e-06 27.4 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFM69898.1 - 0.00011 21.4 0.2 0.00014 21.1 0.2 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain ApbA PF02558.16 KFM69898.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KFM69898.1 - 0.0011 19.0 0.1 0.002 18.2 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KFM69898.1 - 0.0058 16.0 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KFM69898.1 - 0.0068 15.7 0.1 0.013 14.8 0.1 1.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 KFM69898.1 - 0.0089 16.3 0.7 0.014 15.6 0.2 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KFM69898.1 - 0.013 14.6 0.6 0.015 14.5 0.6 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 KFM69898.1 - 0.022 15.2 0.2 0.047 14.1 0.2 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 KFM69898.1 - 0.048 13.9 0.5 0.19 12.0 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain Dak1 PF02733.17 KFM69898.1 - 0.072 12.0 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Dak1 domain Methyltransf_25 PF13649.6 KFM69898.1 - 0.11 13.2 0.1 0.45 11.3 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain DUF1776 PF08643.10 KFM69898.1 - 0.13 11.6 0.0 0.52 9.6 0.0 1.7 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) HTH_Tnp_Tc3_2 PF01498.18 KFM69899.1 - 0.088 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Transposase zf-H2C2_2 PF13465.6 KFM69900.1 - 6e-17 61.2 18.5 6.3e-08 32.7 2.3 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM69900.1 - 2.7e-15 55.9 17.6 5.1e-05 23.5 0.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM69900.1 - 5.9e-11 42.2 14.1 0.002 18.8 2.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM69900.1 - 0.001 18.9 8.4 0.23 11.4 0.5 3.4 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFM69900.1 - 0.0018 18.5 2.4 12 6.3 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KFM69900.1 - 0.012 15.6 7.4 0.88 9.7 7.4 2.6 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.6 KFM69900.1 - 0.048 13.7 5.9 0.96 9.5 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Zf_RING PF16744.5 KFM69900.1 - 0.38 10.9 3.9 0.83 9.8 0.1 2.8 2 1 1 3 3 3 0 KIAA1045 RING finger zinc_ribbon_15 PF17032.5 KFM69900.1 - 0.77 10.6 4.1 2.1 9.2 1.6 2.8 2 1 1 3 3 3 0 zinc-ribbon family ketoacyl-synt PF00109.26 KFM69900.1 - 1.7 8.2 6.5 0.19 11.3 0.5 2.3 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain zf-C2H2_11 PF16622.5 KFM69900.1 - 2 8.2 7.3 17 5.2 0.1 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type Suf PF05843.14 KFM69900.1 - 4.2 7.3 12.8 1 9.3 1.2 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) zf-C2H2_3rep PF18868.1 KFM69900.1 - 9.6 6.9 10.5 0.33 11.6 2.7 2.5 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats Sox17_18_mid PF12067.8 KFM69901.1 - 0.00011 22.2 0.4 0.00043 20.3 0.0 2.3 2 0 0 2 2 2 1 Sox 17/18 central domain Glyco_hydro_59M PF17387.2 KFM69902.1 - 0.0014 18.8 0.0 0.0014 18.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain BROMI PF14961.6 KFM69903.1 - 1.9e-23 82.0 9.2 4.2e-23 80.9 9.0 1.6 1 1 0 1 1 1 1 Broad-minded protein XPG_N PF00752.17 KFM69903.1 - 0.11 13.0 0.1 0.37 11.3 0.1 1.9 1 1 1 2 2 2 0 XPG N-terminal domain BROMI PF14961.6 KFM69904.1 - 1.4e-25 89.1 4.9 3.4e-25 87.8 4.9 1.7 1 1 0 1 1 1 1 Broad-minded protein MIP PF00230.20 KFM69905.1 - 3.9e-33 115.1 4.4 4.5e-33 114.9 4.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein ThrE PF06738.12 KFM69905.1 - 0.0065 15.9 0.1 0.027 13.9 0.0 1.8 2 0 0 2 2 2 1 Putative threonine/serine exporter WWE PF02825.20 KFM69906.1 - 3.4e-16 59.6 2.3 6.2e-16 58.7 2.3 1.4 1 0 0 1 1 1 1 WWE domain zf-C3HC4_3 PF13920.6 KFM69906.1 - 9.2e-09 35.0 13.1 2e-08 34.0 13.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM69906.1 - 1.2e-05 25.6 12.9 2.6e-05 24.5 12.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFM69906.1 - 2.3e-05 24.2 13.7 5.1e-05 23.0 13.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM69906.1 - 6.1e-05 22.9 13.7 0.00014 21.7 13.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM69906.1 - 0.00061 19.6 10.8 0.0013 18.6 10.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFM69906.1 - 0.00073 19.5 10.1 0.0014 18.7 9.5 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 KFM69906.1 - 0.0011 19.0 8.0 0.0026 17.9 8.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 KFM69906.1 - 0.0059 16.4 14.1 0.011 15.5 14.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFM69906.1 - 0.045 13.9 12.7 0.045 13.9 12.7 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING JAB PF01398.21 KFM69907.1 - 2e-15 56.8 0.1 2.3e-15 56.6 0.1 1.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RRM_1 PF00076.22 KFM69908.1 - 5.9e-08 32.4 0.0 7.3e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM69908.1 - 0.014 15.5 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif F_actin_cap_B PF01115.17 KFM69909.1 - 2.5e-107 357.9 0.0 3e-107 357.7 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 KFM69909.1 - 0.049 13.1 0.4 0.33 10.3 0.2 2.5 1 1 0 1 1 1 0 F-actin capping protein alpha subunit zf-CCHC_4 PF14392.6 KFM69911.1 - 0.1 12.3 15.3 0.11 12.2 2.0 2.7 3 0 0 3 3 3 0 Zinc knuckle GYF_2 PF14237.6 KFM69911.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 GYF domain 2 zf-CCHC_6 PF15288.6 KFM69911.1 - 0.62 10.0 14.7 2.5 8.0 2.9 3.3 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC PF00098.23 KFM69911.1 - 4.1 7.6 17.3 0.18 12.0 2.4 3.8 4 0 0 4 4 4 0 Zinc knuckle CLIP1_ZNF PF16641.5 KFM69911.1 - 8 6.5 7.0 32 4.6 1.2 3.0 3 1 0 3 3 3 0 CLIP1 zinc knuckle Tup_N PF08581.10 KFM69912.1 - 0.00019 21.7 7.3 0.00024 21.3 7.3 1.2 1 0 0 1 1 1 1 Tup N-terminal Med30 PF11315.8 KFM69912.1 - 0.0057 16.9 0.6 0.0064 16.7 0.6 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 Cytochrom_C_2 PF01322.20 KFM69912.1 - 0.024 15.5 4.3 0.029 15.3 4.3 1.1 1 0 0 1 1 1 0 Cytochrome C' HEPN_SAV_6107 PF18726.1 KFM69912.1 - 0.039 14.4 0.3 0.045 14.3 0.3 1.0 1 0 0 1 1 1 0 SAV_6107-like HEPN DUF3450 PF11932.8 KFM69912.1 - 0.15 11.3 6.9 0.17 11.2 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cgr1 PF03879.14 KFM69912.1 - 0.32 11.4 13.7 0.45 10.9 13.7 1.3 1 0 0 1 1 1 0 Cgr1 family Mto2_bdg PF12808.7 KFM69912.1 - 0.46 10.8 0.3 0.46 10.8 0.3 2.9 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF349 PF03993.12 KFM69912.1 - 1.5 9.2 8.6 0.48 10.7 4.7 1.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Myb_DNA-binding PF00249.31 KFM69913.1 - 2.4e-22 78.9 1.1 1.8e-13 50.4 0.0 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM69913.1 - 5e-15 55.5 1.2 5.8e-08 32.9 0.5 4.7 2 1 3 5 5 5 3 Myb-like DNA-binding domain SLIDE PF09111.10 KFM69913.1 - 4.3e-07 29.9 7.2 0.0061 16.6 0.0 4.2 3 1 1 4 4 4 2 SLIDE SANT_DAMP1_like PF16282.5 KFM69913.1 - 0.0017 18.5 1.9 0.21 11.8 0.2 2.9 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 KFM69913.1 - 0.0042 16.9 0.3 0.0042 16.9 0.3 4.1 3 1 1 4 4 4 1 Myb DNA-binding like SPT6_acidic PF14632.6 KFM69913.1 - 0.011 16.3 2.4 0.011 16.3 2.4 4.0 3 1 0 3 3 3 0 Acidic N-terminal SPT6 GST_N_4 PF17172.4 KFM69913.1 - 0.031 15.0 0.2 0.22 12.3 0.1 2.2 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Myb_DNA-bind_2 PF08914.11 KFM69913.1 - 0.045 13.9 0.3 1.9 8.8 0.1 3.3 1 1 1 2 2 2 0 Rap1 Myb domain SecIII_SopE_N PF05364.14 KFM69913.1 - 0.14 12.3 0.6 0.45 10.6 0.5 1.9 2 0 0 2 2 2 0 Salmonella type III secretion SopE effector N-terminus PdaC PF13739.6 KFM69913.1 - 2 9.5 3.8 22 6.1 0.0 3.6 3 0 0 3 3 3 0 Deacetylase PdaC HTH_Tnp_Tc3_2 PF01498.18 KFM69914.1 - 4.9e-16 58.7 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69914.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69914.1 - 2e-07 30.7 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69914.1 - 0.0023 17.7 0.6 0.0075 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69914.1 - 0.027 14.6 0.4 0.09 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM69914.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Integrase_H2C2 PF17921.1 KFM69915.1 - 1.1e-07 31.8 2.7 1.1e-07 31.8 2.7 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM69915.1 - 0.00051 20.2 1.0 0.0014 18.8 1.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Ribosomal_L14e PF01929.17 KFM69916.1 - 3.8e-26 91.4 10.6 5.1e-26 91.0 10.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KFM69916.1 - 0.038 14.0 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 KOW motif Transposase_1 PF01359.18 KFM69917.1 - 2.8e-05 23.8 0.0 3.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Transposase (partial DDE domain) Pkinase PF00069.25 KFM69918.1 - 8.4e-61 205.6 0.0 1.1e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM69918.1 - 8e-46 156.4 0.0 1.2e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFM69918.1 - 4.4e-21 74.9 0.4 1.1e-20 73.6 0.4 1.7 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 KFM69918.1 - 4.1e-06 25.8 0.2 1.3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFM69918.1 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like CPSF100_C PF13299.6 KFM69918.1 - 0.053 13.7 0.5 0.12 12.6 0.5 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SMC_N PF02463.19 KFM69920.1 - 2.7e-27 95.6 21.9 2.7e-27 95.6 21.9 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFM69920.1 - 2.4e-23 82.7 0.0 8.2e-23 80.9 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain KRTDAP PF15200.6 KFM69920.1 - 0.031 14.0 0.6 0.13 12.1 0.6 2.1 1 0 0 1 1 1 0 Keratinocyte differentiation-associated DUF2019 PF09450.10 KFM69920.1 - 0.081 12.9 6.9 0.079 12.9 0.3 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2019) Alph_Pro_TM PF09608.10 KFM69920.1 - 4.5 7.0 7.7 0.74 9.6 1.1 2.9 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) DDE_Tnp_1_7 PF13843.6 KFM69921.1 - 2.7e-66 224.3 3.2 3.4e-66 223.9 3.2 1.1 1 0 0 1 1 1 1 Transposase IS4 Peptidase_M54 PF07998.11 KFM69921.1 - 0.018 15.0 0.2 0.043 13.8 0.2 1.6 1 0 0 1 1 1 0 Peptidase family M54 Pex14_N PF04695.13 KFM69921.1 - 0.044 14.4 0.4 0.11 13.1 0.4 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rad50_zn_hook PF04423.14 KFM69921.1 - 2.5 8.0 5.6 20 5.1 0.8 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif DM13 PF10517.9 KFM69922.1 - 1.6e-32 112.2 0.1 2e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 Electron transfer DM13 DM13 PF10517.9 KFM69923.1 - 9.5e-50 167.5 0.1 7.2e-31 106.9 0.1 2.6 2 0 0 2 2 2 2 Electron transfer DM13 DOMON PF03351.17 KFM69923.1 - 8.1e-23 81.0 0.0 1.8e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 DOMON domain Inhibitor_I71 PF12628.7 KFM69923.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DEAD PF00270.29 KFM69924.1 - 3.9e-48 163.5 0.0 1.5e-47 161.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM69924.1 - 6.2e-32 110.2 0.0 2.1e-30 105.3 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 KFM69924.1 - 0.00053 19.9 2.5 0.00096 19.1 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Helicase_C_4 PF13871.6 KFM69924.1 - 0.00086 19.1 1.4 0.37 10.4 0.6 2.4 2 0 0 2 2 2 2 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 KFM69924.1 - 0.001 19.1 0.0 0.003 17.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KFM69924.1 - 0.0021 16.9 0.0 0.0072 15.1 0.0 1.8 1 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SecA_DEAD PF07517.14 KFM69924.1 - 0.01 15.1 0.4 0.034 13.5 0.3 1.9 2 1 0 2 2 2 0 SecA DEAD-like domain FKBP_N PF01346.18 KFM69924.1 - 0.081 13.9 3.5 0.35 11.8 3.5 2.2 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase zf-CCHC_4 PF14392.6 KFM69924.1 - 0.21 11.4 1.5 0.51 10.1 0.4 2.1 2 0 0 2 2 2 0 Zinc knuckle FAP206 PF12018.8 KFM69925.1 - 1.2e-05 25.0 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function YHS PF04945.13 KFM69925.1 - 0.057 13.5 0.2 0.098 12.8 0.2 1.4 1 0 0 1 1 1 0 YHS domain FAP206 PF12018.8 KFM69926.1 - 5.8e-19 68.6 3.8 9.5e-19 68.0 3.8 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF2746 PF10874.8 KFM69926.1 - 0.065 13.7 0.1 0.15 12.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2746) STAR_dimer PF16544.5 KFM69926.1 - 0.55 9.9 3.4 0.3 10.7 0.6 2.1 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein DCB PF16213.5 KFM69927.1 - 0.0031 17.2 2.3 0.54 9.9 0.5 2.1 1 1 1 2 2 2 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF629 PF04780.12 KFM69927.1 - 0.12 10.9 3.3 0.21 10.1 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) UbiA PF01040.18 KFM69928.1 - 3.1e-47 161.0 11.2 3.6e-47 160.8 11.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Arteri_Gl PF00951.18 KFM69928.1 - 0.12 12.2 1.3 0.2 11.5 1.3 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein NYD-SP28_assoc PF14775.6 KFM69930.1 - 0.022 14.8 0.2 0.037 14.1 0.2 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF5311 PF17238.2 KFM69930.1 - 0.1 12.5 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5311) zf-C2H2_4 PF13894.6 KFM69931.1 - 2.4e-10 40.4 16.3 0.0056 17.4 0.1 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM69931.1 - 1.9e-08 34.3 21.9 0.00083 19.7 0.1 4.4 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM69931.1 - 4.9e-07 29.6 7.9 0.00069 19.6 0.1 3.7 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM69931.1 - 1.1e-05 25.6 9.0 5.8e-05 23.3 0.2 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Gin PF10764.9 KFM69931.1 - 0.0026 17.7 0.6 0.5 10.4 0.1 2.7 2 0 0 2 2 2 1 Inhibitor of sigma-G Gin zf_C2H2_ZHX PF18387.1 KFM69931.1 - 0.0038 16.8 7.9 0.059 13.0 0.2 3.4 3 0 0 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain gp32 PF08804.10 KFM69931.1 - 0.013 15.5 1.0 0.018 15.1 1.0 1.2 1 0 0 1 1 1 0 gp32 DNA binding protein like zf_UBZ PF18439.1 KFM69931.1 - 0.023 14.3 6.2 1.6 8.4 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFM69931.1 - 0.03 14.7 12.1 0.11 13.0 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFM69931.1 - 0.034 14.6 14.5 1.9 9.1 0.1 4.6 3 2 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM69931.1 - 0.05 13.4 0.1 0.05 13.4 0.1 5.2 6 2 0 6 6 6 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM69931.1 - 0.11 12.8 10.9 0.3 11.4 1.1 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding PhnA_Zn_Ribbon PF08274.12 KFM69931.1 - 2.5 8.1 7.3 41 4.2 0.3 3.6 3 0 0 3 3 3 0 PhnA Zinc-Ribbon E6 PF00518.17 KFM69931.1 - 3.9 8.0 9.8 3.6 8.1 2.0 2.7 1 1 2 3 3 3 0 Early Protein (E6) DUF4833 PF16117.5 KFM69932.1 - 0.019 15.0 0.1 0.029 14.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4833) Nup35_RRM PF05172.13 KFM69933.1 - 1.1e-14 54.2 0.2 2.3e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KFM69933.1 - 1.1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4171 PF13775.6 KFM69933.1 - 0.87 10.0 5.7 0.55 10.7 2.4 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4171) CLTH PF10607.9 KFM69936.1 - 1.3e-35 122.4 4.8 1.8e-35 122.0 4.8 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFM69936.1 - 7.2e-10 38.5 0.0 1.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 LisH TINF2_N PF14973.6 KFM69936.1 - 0.0042 17.4 3.0 0.0056 17.0 0.5 2.2 1 1 1 2 2 2 1 TERF1-interacting nuclear factor 2 N-terminus MutS_III PF05192.18 KFM69936.1 - 0.063 13.5 6.0 0.13 12.5 6.0 1.5 1 1 0 1 1 1 0 MutS domain III HTH_3 PF01381.22 KFM69936.1 - 0.44 10.7 3.0 3.9 7.6 0.6 3.0 3 0 0 3 3 3 0 Helix-turn-helix IBN_N PF03810.19 KFM69940.1 - 7.3e-11 41.8 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KFM69940.1 - 0.0014 19.0 0.1 0.0017 18.7 0.1 1.1 1 0 0 1 1 1 1 HEAT repeats DDE_3 PF13358.6 KFM69943.1 - 3.2e-12 46.4 0.1 3.2e-12 46.4 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69945.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69945.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69945.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69945.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69945.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain MBOAT PF03062.19 KFM69946.1 - 1.5 8.1 14.4 1.8 7.8 14.4 1.1 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family Ig_3 PF13927.6 KFM69949.1 - 3.7e-56 187.6 1.6 4.2e-15 56.1 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFM69949.1 - 1.7e-52 175.5 0.3 1e-15 57.6 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM69949.1 - 6.5e-40 135.3 0.2 5.4e-09 36.3 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFM69949.1 - 1.1e-36 124.9 0.1 2.6e-08 33.9 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 KFM69949.1 - 8.1e-23 80.6 0.0 1.2e-10 41.6 0.0 3.2 3 0 0 3 3 3 2 Fibronectin type III domain V-set PF07686.17 KFM69949.1 - 1.1e-19 70.6 4.7 0.00068 19.8 0.0 7.4 6 2 2 8 8 8 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM69949.1 - 1.6e-09 37.7 0.1 0.27 11.4 0.0 4.5 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM69949.1 - 4.1e-06 27.0 0.3 2.4 8.5 0.0 5.5 6 0 0 6 6 5 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFM69949.1 - 0.00014 21.4 0.0 0.85 9.2 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 KFM69949.1 - 0.00033 21.0 0.5 4.5 7.7 0.0 5.6 6 1 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFM69949.1 - 0.0016 18.4 0.1 5.2 7.2 0.0 4.9 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM69949.1 - 0.0021 18.6 0.2 0.75 10.4 0.0 3.2 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Amnionless PF14828.6 KFM69949.1 - 0.009 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Amnionless Rtt102p PF09510.10 KFM69950.1 - 0.051 13.8 1.6 1.6 9.0 0.1 2.1 1 1 1 2 2 2 0 Rtt102p-like transcription regulator protein Torus PF16131.5 KFM69950.1 - 0.19 12.5 2.2 2.1 9.1 0.8 2.5 1 1 1 2 2 2 0 Torus domain DDE_3 PF13358.6 KFM69951.1 - 0.0096 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Casc1 PF12366.8 KFM69951.1 - 0.13 11.8 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DDE_3 PF13358.6 KFM69952.1 - 6.1e-16 58.5 0.1 7.3e-15 55.0 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69952.1 - 8.1e-16 58.0 6.5 1.7e-15 57.0 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69952.1 - 0.00085 19.9 1.5 0.00085 19.9 1.5 3.3 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69952.1 - 0.0012 18.6 0.0 0.051 13.4 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM69952.1 - 0.0025 17.6 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Tc3 transposase HTH_28 PF13518.6 KFM69952.1 - 0.014 15.5 0.1 0.066 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69952.1 - 0.026 14.5 2.1 0.037 14.1 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM69955.1 - 6.2e-16 58.5 0.1 7.7e-15 54.9 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69955.1 - 8.2e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69955.1 - 0.00093 19.8 2.1 0.00093 19.8 2.1 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69955.1 - 0.0041 16.9 0.2 0.17 11.7 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69955.1 - 0.022 14.9 0.1 0.088 12.9 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69955.1 - 0.045 13.8 2.4 0.048 13.7 0.3 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM69957.1 - 2.4e-16 59.7 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69957.1 - 9.8e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69958.1 - 2.7e-16 59.6 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69958.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69958.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69958.1 - 0.0023 17.7 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69958.1 - 0.025 14.7 0.4 0.082 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM69958.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Prokineticin PF06607.11 KFM69959.1 - 3e-06 27.4 2.2 3.9e-06 27.1 2.2 1.2 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM69959.1 - 3.9e-06 27.4 8.6 3.9e-06 27.4 8.6 1.3 1 1 0 1 1 1 1 MIT-like atracotoxin family Dickkopf_N PF04706.12 KFM69959.1 - 0.2 12.2 8.4 2.7 8.6 8.4 2.2 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region ACI44 PF15270.6 KFM69959.1 - 0.84 9.9 7.7 9.1 6.6 7.7 2.2 1 1 0 1 1 1 0 Metallo-carboxypeptidase inhibitor DX PF01666.17 KFM69959.1 - 2.1 8.9 9.2 0.99 9.9 4.1 2.2 1 1 1 2 2 2 0 DX module Prokineticin PF06607.11 KFM69960.1 - 5.9e-06 26.5 4.1 7.7e-06 26.2 4.1 1.2 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM69960.1 - 0.002 18.7 6.4 0.0029 18.1 6.4 1.3 1 0 0 1 1 1 1 MIT-like atracotoxin family Colipase_C PF02740.14 KFM69960.1 - 0.021 15.0 0.7 0.021 15.0 0.7 2.3 2 0 0 2 2 2 0 Colipase, C-terminal domain Prokineticin PF06607.11 KFM69961.1 - 4e-07 30.2 6.1 5e-07 30.0 6.1 1.1 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM69961.1 - 0.0035 17.9 8.7 0.0055 17.3 8.7 1.3 1 0 0 1 1 1 1 MIT-like atracotoxin family ACI44 PF15270.6 KFM69961.1 - 0.48 10.7 10.9 18 5.6 10.9 2.3 1 1 0 1 1 1 0 Metallo-carboxypeptidase inhibitor HTH_Tnp_Tc3_2 PF01498.18 KFM69962.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69962.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69963.1 - 2.5e-16 59.7 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69963.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69963.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69963.1 - 0.0023 17.7 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM69963.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM69964.1 - 6.5e-16 58.3 6.5 1.4e-15 57.3 6.5 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69964.1 - 8.4e-16 58.0 0.0 1.2e-14 54.3 0.0 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM69964.1 - 0.00069 20.2 1.5 0.00069 20.2 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69964.1 - 0.0014 18.4 0.6 0.11 12.3 0.0 3.6 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69964.1 - 0.014 15.5 0.1 0.063 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69964.1 - 0.032 14.3 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM69964.1 - 0.089 12.9 0.1 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase RPA_C PF08784.11 KFM69965.1 - 7.1e-08 33.1 0.3 8.6e-08 32.8 0.3 1.2 1 0 0 1 1 1 1 Replication protein A C terminal RNA_pol_Rpb2_7 PF04560.20 KFM69965.1 - 0.12 12.8 0.1 0.26 11.7 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 AMP-binding PF00501.28 KFM69966.1 - 9.3e-50 169.4 0.0 1.1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM69966.1 - 1.7e-08 34.2 2.9 3.8e-08 33.1 2.9 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PNISR PF15996.5 KFM69968.1 - 3.6e-34 118.8 18.8 3.6e-34 118.8 18.8 5.5 2 2 2 4 4 4 1 Arginine/serine-rich protein PNISR Rotamase_2 PF13145.6 KFM69969.1 - 0.03 15.1 3.2 0.042 14.7 3.2 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain Linker_histone PF00538.19 KFM69972.1 - 2.3e-24 85.5 0.9 5.2e-24 84.4 0.9 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF4777 PF16007.5 KFM69972.1 - 0.059 13.6 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Yuri_gagarin PF15934.5 KFM69973.1 - 0.043 13.7 4.1 1.2 8.9 0.8 2.0 1 1 1 2 2 2 0 Yuri gagarin ETAA1 PF15350.6 KFM69973.1 - 0.058 11.7 6.6 0.062 11.6 6.6 1.1 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue DEAD PF00270.29 KFM69974.1 - 3.1e-08 33.6 0.0 3.3e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM69974.1 - 0.025 14.6 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFM69975.1 - 2.2e-10 40.8 0.0 5e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM69975.1 - 1.4e-07 31.5 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase RQC PF09382.10 KFM69976.1 - 2.1e-19 69.4 0.0 5e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 KFM69976.1 - 2.7e-18 65.7 0.0 6e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 HRDC domain HTH_40 PF14493.6 KFM69976.1 - 3.6e-15 56.2 0.0 7.4e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain RecQ_Zn_bind PF16124.5 KFM69976.1 - 8.3e-07 29.6 1.8 2.3e-06 28.2 1.8 1.8 1 0 0 1 1 1 1 RecQ zinc-binding Sigma70_r4_2 PF08281.12 KFM69976.1 - 0.32 10.7 1.8 0.57 9.9 0.2 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_Tc3_2 PF01498.18 KFM69977.1 - 1.9e-16 60.0 2.2 4.5e-16 58.8 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM69977.1 - 9.6e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CRF PF00473.17 KFM69978.1 - 8.4e-12 45.0 4.4 1.3e-11 44.3 4.4 1.3 1 0 0 1 1 1 1 Corticotropin-releasing factor family Selenoprotein_S PF06936.11 KFM69978.1 - 0.022 14.6 0.2 0.033 14.0 0.2 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) ELH PF02323.15 KFM69978.1 - 0.035 13.5 0.9 0.058 12.8 1.0 1.4 1 1 0 1 1 1 0 Egg-laying hormone precursor Acyl_transf_3 PF01757.22 KFM69979.1 - 9.9e-08 31.4 28.4 1.2e-07 31.1 28.4 1.1 1 0 0 1 1 1 1 Acyltransferase family OAD_gamma PF04277.13 KFM69980.1 - 0.054 14.1 0.1 0.2 12.3 0.0 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF3671 PF12420.8 KFM69980.1 - 0.082 13.0 0.7 0.39 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function F-box-like PF12937.7 KFM69981.1 - 6.1e-07 29.2 1.6 1.6e-06 27.9 1.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM69981.1 - 2.1e-06 27.4 0.6 5.3e-06 26.2 0.6 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 KFM69981.1 - 1.3e-05 25.9 1.7 0.0031 18.3 0.1 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat F-box_4 PF15966.5 KFM69981.1 - 0.057 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 F-box DM4_12 PF07841.13 KFM69982.1 - 0.0096 16.6 0.6 0.019 15.6 0.6 1.4 1 0 0 1 1 1 1 DM4/DM12 family HHV-5_US34A PF17087.5 KFM69982.1 - 0.044 13.9 0.7 0.097 12.8 0.2 1.9 2 0 0 2 2 2 0 Herpesvirus US34A protein family T6PP_N PF18572.1 KFM69982.1 - 0.072 12.9 0.0 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain HTH_Tnp_Tc3_2 PF01498.18 KFM69983.1 - 3e-16 59.4 3.0 6.3e-16 58.4 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM69983.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM69983.1 - 3e-07 30.1 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM69983.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69983.1 - 0.03 14.5 0.4 0.098 12.8 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM69983.1 - 2.8 8.6 15.6 0.13 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain SLC35F PF06027.12 KFM69984.1 - 3.7e-13 49.6 5.1 5.7e-13 49.0 5.1 1.2 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KFM69984.1 - 2.6e-09 37.4 16.6 2.8e-07 30.8 7.1 2.7 2 2 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KFM69984.1 - 1.5e-08 34.2 1.9 1.7e-08 34.0 1.9 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 KFM69984.1 - 8.8e-07 28.2 7.7 1.3e-06 27.6 7.7 1.3 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KFM69984.1 - 0.00071 19.0 2.1 0.0013 18.2 2.1 1.6 1 0 0 1 1 1 1 Triose-phosphate Transporter family UPF0060 PF02694.15 KFM69984.1 - 0.019 15.2 1.8 0.063 13.5 1.8 1.8 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family BTB PF00651.31 KFM69985.1 - 1.6e-23 83.0 0.0 2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain CBM_14 PF01607.24 KFM69986.1 - 1.6e-35 121.0 28.3 1.3e-12 47.7 3.5 3.3 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain DUF3853 PF12964.7 KFM69986.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) DSPc PF00782.20 KFM69987.1 - 2.4e-26 92.1 0.0 4.4e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KFM69987.1 - 0.0012 18.5 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KFM69987.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Exog_C PF18026.1 KFM69987.1 - 0.093 12.8 0.1 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Zn_Tnp_IS1 PF03811.13 KFM69987.1 - 8.2 6.3 8.0 34 4.3 0.1 2.5 2 0 0 2 2 2 0 InsA N-terminal domain Mtf2_C PF14061.6 KFM69988.1 - 2e-22 79.1 0.0 4.6e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Chromo PF00385.24 KFM69988.1 - 0.045 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Tudor_2 PF18104.1 KFM69990.1 - 1.4e-11 43.9 0.0 2.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain PHD PF00628.29 KFM69990.1 - 2e-11 43.6 5.6 3e-11 43.0 5.6 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KFM69990.1 - 0.0011 18.9 4.6 0.0011 18.9 4.6 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 KFM69990.1 - 0.0036 16.9 2.4 0.0064 16.1 2.4 1.5 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHF5 PF03660.14 KFM69990.1 - 0.0048 17.1 2.7 0.008 16.4 2.7 1.3 1 0 0 1 1 1 1 PHF5-like protein LBR_tudor PF09465.10 KFM69990.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain PHD_2 PF13831.6 KFM69990.1 - 0.012 15.1 9.7 0.012 15.1 9.7 2.4 2 1 0 2 2 2 0 PHD-finger Ephrin_rec_like PF07699.13 KFM69990.1 - 0.47 10.3 6.7 0.82 9.5 2.7 2.3 2 0 0 2 2 2 0 Putative ephrin-receptor like DOMON PF03351.17 KFM69991.1 - 2.3e-09 37.6 0.0 3.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 DOMON domain RRP36 PF06102.12 KFM69992.1 - 1.9e-43 148.3 24.8 2.2e-43 148.1 24.8 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 Macoilin PF09726.9 KFM69992.1 - 1.9 7.0 14.4 2.3 6.7 14.4 1.1 1 0 0 1 1 1 0 Macoilin family TF_Zn_Ribbon PF08271.12 KFM69993.1 - 2.6e-09 36.5 0.2 2.9e-09 36.3 0.2 1.1 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KFM69993.1 - 0.0022 17.3 0.5 0.024 14.0 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain A2L_zn_ribbon PF08792.10 KFM69993.1 - 0.039 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain DDE_3 PF13358.6 KFM69994.1 - 5.4e-16 58.7 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM69994.1 - 8e-16 58.1 6.5 1.4e-15 57.3 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM69994.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM69994.1 - 0.0021 17.8 0.1 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM69994.1 - 0.014 15.5 0.1 0.063 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM69994.1 - 0.032 14.2 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix TFIIB PF00382.19 KFM69995.1 - 2.6e-54 181.2 1.5 1.2e-27 95.7 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.23 KFM69995.1 - 3.1e-06 27.0 0.0 0.003 17.3 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFM69995.1 - 4.4e-05 23.6 0.1 0.056 13.5 0.0 2.2 2 1 0 2 2 2 2 Cyclin, C-terminal domain RB_B PF01857.20 KFM69995.1 - 0.00072 19.6 0.0 0.0015 18.5 0.0 1.7 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Sigma70_r4 PF04545.16 KFM69995.1 - 0.027 14.0 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HcyBio PF01837.16 KFM69995.1 - 0.092 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation Trypsin PF00089.26 KFM69996.1 - 9.4e-63 212.0 0.0 1.2e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 KFM69996.1 - 6.9e-07 29.1 0.0 0.0038 16.8 0.0 2.3 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.11 KFM69996.1 - 4e-06 27.2 0.0 9.5e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) CLIP PF12032.8 KFM69996.1 - 5.8e-06 26.5 1.7 1.8e-05 24.9 1.7 1.9 1 1 0 1 1 1 1 Regulatory CLIP domain of proteinases Trypsin_2 PF13365.6 KFM69996.1 - 3.1e-05 24.9 0.0 6.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain SNAP PF14938.6 KFM69997.1 - 1.6e-78 264.0 11.8 1.8e-78 263.8 11.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KFM69997.1 - 1.5e-06 27.9 15.4 0.0021 18.0 0.3 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM69997.1 - 6.3e-06 26.4 11.6 8.8e-05 22.7 1.9 3.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM69997.1 - 0.00015 21.5 7.1 0.24 11.5 0.2 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM69997.1 - 0.00037 20.0 2.0 0.00052 19.5 2.0 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_6 PF13174.6 KFM69997.1 - 0.0018 18.8 7.4 3 8.7 0.2 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 KFM69997.1 - 0.0085 16.1 16.5 0.074 13.1 1.0 5.2 4 2 1 5 5 5 1 MIT (microtubule interacting and transport) domain NSF PF02071.20 KFM69997.1 - 0.011 16.3 16.3 5.1 8.3 0.4 6.9 7 0 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat Spatacsin_C PF14649.6 KFM69997.1 - 0.013 14.6 7.3 0.5 9.4 1.4 2.8 1 1 2 3 3 3 0 Spatacsin C-terminus TPR_14 PF13428.6 KFM69997.1 - 0.02 15.7 7.7 0.38 11.7 0.2 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 KFM69997.1 - 0.025 14.3 1.6 0.081 12.6 0.1 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 HrpF PF06266.12 KFM69997.1 - 0.037 14.3 0.0 0.17 12.2 0.0 2.1 1 0 0 1 1 1 0 HrpF protein TPR_8 PF13181.6 KFM69997.1 - 0.11 12.8 8.9 0.71 10.2 0.2 4.2 4 1 0 4 4 3 0 Tetratricopeptide repeat DUF4368 PF14287.6 KFM69997.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) TPR_10 PF13374.6 KFM69997.1 - 0.12 12.2 5.8 9.3 6.3 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat PhageMin_Tail PF10145.9 KFM69997.1 - 0.14 12.0 3.0 0.18 11.7 0.2 2.2 2 1 0 2 2 2 0 Phage-related minor tail protein TPR_1 PF00515.28 KFM69997.1 - 0.18 11.7 0.3 0.18 11.7 0.3 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFM69997.1 - 0.2 12.3 2.6 3.9 8.4 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Stress-antifung PF01657.17 KFM69997.1 - 0.31 11.7 3.1 0.45 11.2 1.6 2.1 1 1 1 2 2 2 0 Salt stress response/antifungal CBP PF12192.8 KFM69997.1 - 0.6 10.3 3.8 2.3 8.5 0.0 3.0 4 0 0 4 4 2 0 Fungal calcium binding protein TPR_19 PF14559.6 KFM69997.1 - 0.66 10.5 9.1 2.4 8.7 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM69997.1 - 1.1 9.0 6.5 0.69 9.6 0.5 3.3 3 0 0 3 3 3 0 TPR repeat FRB_dom PF08771.11 KFM69997.1 - 1.2 9.6 5.5 1.7 9.1 0.2 3.0 3 1 0 3 3 3 0 FKBP12-rapamycin binding domain TPR_16 PF13432.6 KFM69997.1 - 2.8 8.6 10.3 0.87 10.3 0.7 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 KFM69997.1 - 7.2 6.3 9.4 2.4 7.8 5.4 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) BACK PF07707.15 KFM69998.1 - 6.7e-17 61.5 0.2 5.2e-16 58.6 0.2 2.3 1 1 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFM69999.1 - 2e-22 79.5 0.2 2.2e-21 76.1 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM69999.1 - 1.2e-10 41.4 5.9 3.2e-08 33.6 1.3 3.9 2 2 2 4 4 4 2 BTB And C-terminal Kelch RVT_1 PF00078.27 KFM70000.1 - 1.3e-38 132.8 1.4 2e-38 132.1 1.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 KFM70001.1 - 3.8e-16 59.2 0.1 6.3e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70001.1 - 7.8e-16 58.1 6.5 1.4e-15 57.3 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM70001.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70001.1 - 0.0024 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70001.1 - 0.015 15.4 0.1 0.063 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM70001.1 - 0.034 14.2 0.4 0.034 14.2 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM70002.1 - 6.4e-16 58.4 6.5 1e-15 57.7 6.5 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM70002.1 - 0.0005 20.6 1.5 0.0005 20.6 1.5 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM70002.1 - 0.015 15.3 1.9 0.027 14.5 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 KFM70002.1 - 0.02 14.7 1.9 0.21 11.5 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Sec3_C_2 PF15278.6 KFM70003.1 - 0.032 14.6 1.1 0.16 12.4 0.3 2.2 1 1 1 2 2 2 0 Sec3 exocyst complex subunit BING4CT PF08149.11 KFM70003.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 BING4CT (NUC141) domain SET PF00856.28 KFM70004.1 - 5.8e-16 59.3 0.1 1.1e-15 58.5 0.0 1.4 2 0 0 2 2 2 1 SET domain RibD_C PF01872.17 KFM70004.1 - 0.087 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 RibD C-terminal domain SRI PF08236.11 KFM70005.1 - 4.8e-25 87.5 5.4 4.8e-25 87.5 5.4 2.4 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 KFM70005.1 - 1e-09 38.3 2.5 1e-09 38.3 2.5 2.3 2 0 0 2 2 2 1 WW domain Rhomboid_SP PF12595.8 KFM70005.1 - 0.0035 16.7 0.2 0.0091 15.4 0.2 1.7 1 0 0 1 1 1 1 Rhomboid serine protease Med26 PF08711.11 KFM70005.1 - 0.44 10.6 0.0 0.44 10.6 0.0 3.3 3 1 0 3 3 3 0 TFIIS helical bundle-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM70006.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70006.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Alpha_L_fucos PF01120.17 KFM70007.1 - 4.2e-122 407.9 6.8 5.8e-122 407.5 6.8 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 KFM70007.1 - 2.3e-24 85.8 0.5 4.2e-24 84.9 0.5 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain GHL6 PF14871.6 KFM70007.1 - 0.021 15.0 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Ras PF00071.22 KFM70010.1 - 3.6e-40 137.2 0.0 5e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM70010.1 - 3.3e-13 49.9 0.0 5.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM70010.1 - 4.5e-09 36.0 0.0 6.1e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFM70010.1 - 1.5e-05 25.0 0.1 0.0013 18.6 0.2 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFM70010.1 - 3.4e-05 23.5 0.1 7.6e-05 22.3 0.1 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PAP2 PF01569.21 KFM70012.1 - 3.3e-26 91.7 0.9 7e-26 90.6 0.9 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFM70012.1 - 1.6e-07 31.2 0.1 7.3e-07 29.1 0.1 2.0 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFM70012.1 - 4.8e-07 30.2 4.1 4.8e-07 30.2 4.1 1.8 2 0 0 2 2 1 1 PAP2 superfamily C-terminal DUF996 PF06195.13 KFM70012.1 - 0.024 14.9 1.9 0.071 13.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF996) YbjM PF11045.8 KFM70012.1 - 0.067 13.4 1.2 0.13 12.5 1.2 1.4 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae MNHE PF01899.16 KFM70012.1 - 0.15 11.8 2.0 1.4 8.7 0.6 2.6 2 1 1 3 3 3 0 Na+/H+ ion antiporter subunit DUF2976 PF11190.8 KFM70012.1 - 0.48 10.3 4.7 0.45 10.3 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2976) Colicin_V PF02674.16 KFM70012.1 - 0.7 9.9 7.4 0.091 12.7 1.1 2.5 3 0 0 3 3 3 0 Colicin V production protein HKR_ArcB_TM PF18415.1 KFM70012.1 - 1.8 9.4 7.1 0.3 11.9 1.7 2.4 2 1 1 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain DUF4149 PF13664.6 KFM70012.1 - 2.2 8.7 6.1 19 5.6 2.8 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Polysacc_synt_C PF14667.6 KFM70012.1 - 3.9 7.5 9.1 0.22 11.6 3.1 1.9 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain CENP-T_C PF15511.6 KFM70013.1 - 5.8e-07 29.6 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFM70013.1 - 5.9e-06 26.7 0.2 8.8e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFM70013.1 - 1.5e-05 25.0 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KFM70013.1 - 0.0038 17.6 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein AbiEi_4 PF13338.6 KFM70013.1 - 0.016 15.4 0.6 0.03 14.5 0.6 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Bromo_TP PF07524.13 KFM70013.1 - 0.027 14.5 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated TFIID-18kDa PF02269.16 KFM70013.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.7 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit MFS_1 PF07690.16 KFM70014.1 - 1.4e-27 96.6 47.1 1.3e-23 83.6 32.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM70014.1 - 1.1e-25 90.4 16.7 1.9e-25 89.7 16.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3236 PF11576.8 KFM70014.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) YtpI PF14007.6 KFM70014.1 - 0.83 9.8 7.0 3.4 7.9 7.0 2.0 1 0 0 1 1 1 0 YtpI-like protein Nkap_C PF06047.11 KFM70015.1 - 2e-48 162.7 5.5 2.3e-48 162.5 5.5 1.0 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain MFS_1 PF07690.16 KFM70016.1 - 2.3e-38 132.1 22.5 1.5e-22 80.0 7.3 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 KFM70016.1 - 0.0088 14.7 4.5 0.018 13.7 4.5 1.5 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KFM70019.1 - 4.9e-30 104.7 25.1 3.4e-13 49.2 0.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 KFM70019.1 - 9.1e-10 38.4 14.0 3.9e-09 36.3 11.2 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KFM70019.1 - 0.0025 16.8 14.8 0.009 14.9 3.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.8 KFM70019.1 - 0.0036 16.0 4.0 0.0061 15.2 4.0 1.4 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like TMEM61 PF15105.6 KFM70019.1 - 0.0089 15.9 1.8 1.1 9.1 0.2 2.6 2 0 0 2 2 2 2 TMEM61 protein family EGF_CA PF07645.15 KFM70020.1 - 5.3e-11 42.5 7.3 5.3e-11 42.5 7.3 7.8 5 1 1 7 7 7 1 Calcium-binding EGF domain cEGF PF12662.7 KFM70020.1 - 1.7e-07 31.0 48.4 0.0033 17.3 0.5 7.5 7 0 0 7 7 7 5 Complement Clr-like EGF-like EGF PF00008.27 KFM70020.1 - 2.2e-05 24.6 22.4 0.00013 22.1 6.8 7.8 7 0 0 7 7 7 3 EGF-like domain EGF_3 PF12947.7 KFM70020.1 - 0.00014 22.0 9.7 0.00014 22.0 9.7 8.3 6 2 1 7 7 7 3 EGF domain FXa_inhibition PF14670.6 KFM70020.1 - 0.0033 17.7 7.0 0.0033 17.7 7.0 9.5 5 3 3 8 8 8 2 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 KFM70020.1 - 0.0095 16.0 13.8 0.021 14.9 5.0 6.8 8 0 0 8 8 8 2 MSP1 EGF domain 1 Syndecan PF01034.20 KFM70020.1 - 0.011 15.6 0.3 0.023 14.6 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain EB PF01683.18 KFM70020.1 - 0.013 15.7 3.1 0.013 15.7 3.1 7.8 5 1 0 5 5 5 0 EB module MFS_2 PF13347.6 KFM70020.1 - 0.022 13.3 0.0 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Antistasin PF02822.14 KFM70020.1 - 0.027 15.1 0.4 0.027 15.1 0.4 7.3 6 1 1 7 7 7 0 Antistasin family Arrestin_C PF02752.22 KFM70021.1 - 2.6e-23 82.9 0.0 3.6e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFM70021.1 - 2.3e-14 53.7 0.0 7.8e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KFM70021.1 - 0.034 13.3 0.1 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Rgp1 PBP_GOBP PF01395.22 KFM70022.1 - 0.024 14.8 2.2 0.04 14.1 2.2 1.5 1 0 0 1 1 1 0 PBP/GOBP family WD40_4 PF16300.5 KFM70023.1 - 2.3e-22 78.6 0.1 4.1e-22 77.8 0.1 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFM70023.1 - 3e-13 50.0 2.8 1.5e-05 25.7 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM70023.1 - 5.4e-07 29.8 0.2 0.026 14.8 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Fib_alpha PF08702.10 KFM70023.1 - 0.0025 18.0 0.7 0.004 17.3 0.7 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF1667 PF07892.11 KFM70023.1 - 0.03 14.4 0.4 0.057 13.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) ATP_bind_1 PF03029.17 KFM70025.1 - 1.7e-41 142.6 0.0 1.9e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFM70025.1 - 0.0024 18.3 0.0 0.0076 16.7 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFM70025.1 - 0.0026 18.2 0.0 0.0034 17.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CLP1_P PF16575.5 KFM70025.1 - 0.0066 16.3 0.0 0.009 15.8 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 KFM70025.1 - 0.0067 16.8 0.0 0.0085 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KFM70025.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM70025.1 - 0.019 15.2 0.0 0.03 14.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM70025.1 - 0.023 15.0 0.0 0.051 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KFM70025.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KFM70025.1 - 0.024 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ArsA_ATPase PF02374.15 KFM70025.1 - 0.028 13.6 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_24 PF13479.6 KFM70025.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFM70025.1 - 0.033 14.1 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 KFM70025.1 - 0.038 13.7 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KFM70025.1 - 0.042 14.4 0.0 0.047 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KFM70025.1 - 0.091 13.2 0.1 0.17 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFM70025.1 - 0.16 12.1 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFM70025.1 - 0.17 11.9 0.0 0.2 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KFM70025.1 - 0.17 10.8 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KFM70025.1 - 0.2 12.2 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 KFM70025.1 - 0.22 10.7 0.0 0.29 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.7 KFM70025.1 - 0.23 10.3 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain MINDY_DUB PF04424.13 KFM70026.1 - 4.1e-27 94.5 0.3 1.3e-26 92.9 0.0 2.1 2 1 0 2 2 2 1 MINDY deubiquitinase SBP_bac_3 PF00497.20 KFM70026.1 - 0.12 11.8 0.3 0.22 10.9 0.2 1.3 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Glyco_hydro_8 PF01270.17 KFM70026.1 - 0.14 11.0 0.0 2 7.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 8 CCDC50_N PF15295.6 KFM70026.1 - 0.27 11.4 12.2 0.74 10.0 12.2 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus MFS_1 PF07690.16 KFM70027.1 - 0.0077 15.2 4.7 0.0095 14.9 4.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM70 PF06979.12 KFM70027.1 - 2.5 8.5 8.5 0.73 10.2 1.4 2.1 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex DMAP1 PF05499.12 KFM70028.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.7 1 1 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF3545 PF12065.8 KFM70028.1 - 0.12 12.4 2.7 0.31 11.1 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) I-set PF07679.16 KFM70029.1 - 5e-39 132.3 0.0 7.7e-14 51.5 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin I-set domain fn3 PF00041.21 KFM70029.1 - 2.9e-38 130.1 3.7 1e-17 64.2 0.1 3.7 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.6 KFM70029.1 - 2.9e-34 117.5 4.2 1.8e-10 41.2 0.1 4.5 5 0 0 5 5 5 3 Immunoglobulin domain ig PF00047.25 KFM70029.1 - 6.9e-26 90.2 0.0 8.5e-08 32.3 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM70029.1 - 1e-20 73.9 0.2 4.3e-06 27.0 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM70029.1 - 1.6e-12 47.5 3.7 5.7e-05 23.3 0.0 5.2 4 2 0 4 4 4 3 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFM70029.1 - 2.4e-08 34.4 0.4 0.00062 20.3 0.0 3.7 4 1 0 4 4 3 2 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 KFM70029.1 - 2.3e-06 27.1 0.1 0.031 13.9 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM70029.1 - 7.9e-06 25.9 0.0 0.0052 16.8 0.0 3.2 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM70029.1 - 4.1e-05 23.9 0.0 0.016 15.6 0.0 3.6 4 0 0 4 4 4 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFM70029.1 - 0.00048 20.1 0.0 1.2 9.3 0.0 3.1 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFM70029.1 - 0.0031 17.5 0.1 2.6 8.0 0.0 2.8 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain Interfer-bind PF09294.10 KFM70029.1 - 0.0075 16.6 0.0 5.9 7.3 0.0 2.8 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III PhoD_N PF16655.5 KFM70029.1 - 0.026 15.0 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain DUF2369 PF10179.9 KFM70029.1 - 0.059 13.8 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Ig_3 PF13927.6 KFM70030.1 - 1.1e-21 77.3 0.0 1.2e-13 51.4 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM70030.1 - 1.7e-21 76.1 0.0 5.6e-13 48.8 0.0 2.5 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 KFM70030.1 - 5.8e-15 55.2 0.1 3.9e-08 33.4 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFM70030.1 - 3.1e-13 49.8 0.0 2.5e-08 34.2 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFM70030.1 - 5.5e-06 26.5 0.3 0.53 10.5 0.0 3.5 3 1 1 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM70030.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM70031.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70031.1 - 7.4e-15 55.0 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70031.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70031.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70031.1 - 0.023 14.8 0.4 0.085 13.0 0.4 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM70031.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM70032.1 - 4.8e-09 36.1 0.0 7.1e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70033.1 - 2.5e-16 59.7 2.2 5e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70033.1 - 1.1e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C3HC4_3 PF13920.6 KFM70034.1 - 2.1e-08 33.9 15.6 3.2e-08 33.3 15.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM70034.1 - 0.0004 20.6 18.1 0.00063 20.0 18.1 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFM70034.1 - 0.0011 18.8 13.7 0.0017 18.2 13.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 KFM70034.1 - 0.043 13.5 13.0 0.076 12.7 13.0 1.4 1 0 0 1 1 1 0 P-11 zinc finger Birna_VP3 PF01767.16 KFM70034.1 - 0.093 12.8 0.3 0.11 12.6 0.3 1.1 1 0 0 1 1 1 0 Birnavirus VP3 protein zf-C3HC4_2 PF13923.6 KFM70034.1 - 1.1 9.1 18.8 2.6 8.0 18.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM70034.1 - 6.5 6.8 17.7 14 5.8 17.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain AAA PF00004.29 KFM70035.1 - 4.7e-47 159.7 0.0 1.1e-46 158.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM70035.1 - 1e-10 41.3 0.0 1.7e-05 24.5 0.0 2.6 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KFM70035.1 - 2.4e-06 28.0 0.1 0.0012 19.2 0.1 3.3 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KFM70035.1 - 2.4e-05 24.1 0.0 8.2e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFM70035.1 - 0.00027 21.2 0.1 0.013 15.8 0.0 3.0 1 1 2 3 3 3 1 AAA domain AAA_18 PF13238.6 KFM70035.1 - 0.0018 18.9 0.0 0.0057 17.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KFM70035.1 - 0.0019 18.2 0.1 0.019 15.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFM70035.1 - 0.0031 16.9 1.1 0.0073 15.7 0.1 2.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFM70035.1 - 0.0042 17.3 0.0 0.0091 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFM70035.1 - 0.0047 16.2 0.0 0.0088 15.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 KFM70035.1 - 0.0052 16.4 0.0 0.015 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFM70035.1 - 0.0081 15.4 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Vps4_C PF09336.10 KFM70035.1 - 0.0084 16.1 0.1 0.052 13.6 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 KFM70035.1 - 0.0093 16.1 0.0 0.039 14.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KFM70035.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KFM70035.1 - 0.011 15.5 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KFM70035.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KFM70035.1 - 0.012 16.1 0.2 0.2 12.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 KFM70035.1 - 0.015 14.6 0.5 0.35 10.2 0.0 2.6 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.22 KFM70035.1 - 0.028 13.6 0.1 0.58 9.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RHH_6 PF16762.5 KFM70035.1 - 0.035 14.7 0.1 0.13 12.9 0.0 2.0 2 0 0 2 2 1 0 Ribbon-helix-helix domain NACHT PF05729.12 KFM70035.1 - 0.052 13.5 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 1 0 NACHT domain PhoH PF02562.16 KFM70035.1 - 0.053 13.0 0.0 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Viral_helicase1 PF01443.18 KFM70035.1 - 0.081 12.7 0.0 0.98 9.1 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KFM70035.1 - 0.092 12.5 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFM70035.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KFM70035.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFM70035.1 - 0.2 11.9 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Varsurf_PPLC PF03490.13 KFM70036.1 - 0.003 17.5 0.6 0.0088 16.0 0.0 2.1 3 0 0 3 3 3 1 Variant-surface-glycoprotein phospholipase C PI-PLC-X PF00388.19 KFM70036.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain FANCI_S4 PF14678.6 KFM70037.1 - 0.0017 17.5 2.3 0.0021 17.3 2.3 1.2 1 0 0 1 1 1 1 FANCI solenoid 4 Tma16 PF11176.8 KFM70037.1 - 0.0054 16.6 1.8 0.0078 16.1 1.8 1.2 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF3464 PF11947.8 KFM70037.1 - 0.055 13.2 0.2 0.055 13.2 0.2 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SR-25 PF10500.9 KFM70037.1 - 0.065 12.8 14.5 0.073 12.7 14.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.10 KFM70037.1 - 0.13 12.3 6.4 0.15 12.1 6.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OAD_gamma PF04277.13 KFM70037.1 - 0.41 11.3 1.8 0.56 10.8 1.8 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AP3D1 PF06375.11 KFM70037.1 - 0.7 10.1 13.5 0.83 9.9 13.5 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Med19 PF10278.9 KFM70037.1 - 1.5 8.7 15.0 1.9 8.4 15.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 ETRAMP PF09716.10 KFM70037.1 - 3.8 7.6 13.0 5.9 7.0 13.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4604 PF15377.6 KFM70037.1 - 8.1 6.8 15.1 9.6 6.6 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Tropomyosin PF00261.20 KFM70038.1 - 0.0017 17.8 11.8 0.0017 17.8 11.8 2.7 1 1 1 2 2 1 1 Tropomyosin NYD-SP28_assoc PF14775.6 KFM70038.1 - 0.0017 18.4 15.0 1.3 9.2 0.1 4.2 4 1 0 4 4 3 3 Sperm tail C-terminal domain SLATT_4 PF18186.1 KFM70038.1 - 0.022 14.4 0.6 0.022 14.4 0.6 2.6 3 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 HOOK PF05622.12 KFM70038.1 - 0.03 12.5 38.8 0.0094 14.2 23.1 2.0 1 1 0 2 2 2 0 HOOK protein ZapB PF06005.12 KFM70038.1 - 0.047 14.1 4.5 0.047 14.1 4.5 5.1 3 2 1 4 4 4 0 Cell division protein ZapB Nup54 PF13874.6 KFM70038.1 - 0.14 12.3 18.9 1.9 8.6 11.7 3.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF4407 PF14362.6 KFM70038.1 - 0.14 11.5 16.1 0.024 14.0 6.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_C12 PF01088.21 KFM70038.1 - 0.19 11.5 3.9 0.88 9.3 0.5 2.3 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Jnk-SapK_ap_N PF09744.9 KFM70038.1 - 0.23 11.7 36.2 0.73 10.1 16.0 2.9 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 CCCAP PF15964.5 KFM70038.1 - 0.53 8.5 35.5 0.71 8.1 35.5 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family FAM184 PF15665.5 KFM70038.1 - 1.2 8.9 38.3 0.37 10.6 10.6 3.3 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B ApoO PF09769.9 KFM70038.1 - 1.4 8.9 8.0 9 6.3 0.1 3.3 3 1 0 3 3 3 0 Apolipoprotein O Filament PF00038.21 KFM70038.1 - 1.7 8.1 33.8 4e+02 0.4 32.5 2.5 1 1 0 1 1 1 0 Intermediate filament protein CCDC92 PF14916.6 KFM70038.1 - 3 7.7 18.8 0.095 12.5 0.8 4.0 4 1 1 5 5 5 0 Coiled-coil domain of unknown function DUF724 PF05266.14 KFM70038.1 - 7.5 6.3 28.9 0.052 13.4 9.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) YabA PF06156.13 KFM70039.1 - 0.0041 17.7 4.9 0.0041 17.7 4.9 2.4 1 1 1 2 2 2 1 Initiation control protein YabA ZapB PF06005.12 KFM70039.1 - 0.029 14.8 2.8 0.029 14.8 2.8 3.1 2 1 0 2 2 2 0 Cell division protein ZapB Phe_tRNA-synt_N PF02912.18 KFM70039.1 - 0.03 14.2 11.0 0.096 12.6 0.3 3.4 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF1732 PF08340.11 KFM70039.1 - 0.039 13.9 3.2 0.24 11.4 2.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) Spc7 PF08317.11 KFM70039.1 - 0.041 12.8 15.8 0.13 11.2 15.8 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4158 PF13700.6 KFM70039.1 - 0.043 13.7 0.9 0.058 13.2 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) DUF3926 PF13080.6 KFM70039.1 - 0.07 13.1 3.2 0.17 11.8 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3926) SKA2 PF16740.5 KFM70039.1 - 0.26 11.1 8.4 0.088 12.6 1.1 2.7 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 Mod_r PF07200.13 KFM70039.1 - 1.1 9.4 15.0 0.31 11.2 5.7 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Macoilin PF09726.9 KFM70039.1 - 2.9 6.3 12.4 3.4 6.1 12.4 1.0 1 0 0 1 1 1 0 Macoilin family Plus-3 PF03126.18 KFM70040.1 - 6.1e-34 116.8 0.0 6.1e-34 116.8 0.0 3.2 3 0 0 3 3 3 1 Plus-3 domain NTP_transferase PF00483.23 KFM70041.1 - 7e-54 183.0 0.0 1.1e-53 182.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KFM70041.1 - 6.3e-12 44.7 11.8 1.6e-10 40.3 2.2 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KFM70041.1 - 4.8e-10 40.0 0.0 6.1e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KFM70041.1 - 4.8e-07 29.4 5.2 2.8e-05 23.8 2.0 3.4 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 KFM70041.1 - 0.022 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase IspD PF01128.19 KFM70041.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.12 KFM70041.1 - 0.096 11.6 0.4 0.46 9.4 0.2 2.1 2 1 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 KFM70041.1 - 0.18 9.9 0.3 0.73 7.9 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) EGF_CA PF07645.15 KFM70042.1 - 4e-79 260.6 144.6 1.7e-12 47.3 4.4 11.8 10 1 1 11 11 11 9 Calcium-binding EGF domain cEGF PF12662.7 KFM70042.1 - 1.5e-48 162.3 102.1 1.7e-08 34.2 0.6 12.1 13 0 0 13 13 13 10 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFM70042.1 - 5.2e-26 90.6 150.4 1.3e-06 28.5 4.0 11.2 10 1 1 11 11 11 10 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFM70042.1 - 1.3e-25 89.3 137.6 9.1e-05 22.7 5.8 12.2 11 1 0 11 11 11 10 EGF-like domain hEGF PF12661.7 KFM70042.1 - 1.3e-18 66.9 139.8 0.0013 19.2 6.3 13.7 13 2 1 14 14 14 9 Human growth factor-like EGF EGF_3 PF12947.7 KFM70042.1 - 5.2e-15 55.3 133.1 0.00031 20.9 3.3 11.6 11 0 0 11 11 11 9 EGF domain TB PF00683.17 KFM70042.1 - 1.2e-14 53.7 10.1 1.2e-14 53.7 10.1 3.5 4 0 0 4 4 4 1 TB domain EGF_MSP1_1 PF12946.7 KFM70042.1 - 8e-05 22.6 16.7 0.00053 20.0 2.3 10.1 10 0 0 10 10 10 3 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 KFM70042.1 - 0.0057 16.9 4.2 0.0057 16.9 4.2 10.8 9 1 1 10 10 10 5 Pvs28 EGF domain HTH_Tnp_Tc5 PF03221.16 KFM70044.1 - 1e-07 31.9 0.1 2.3e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KFM70044.1 - 1.5e-05 24.8 0.2 0.012 15.3 0.0 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 KFM70044.1 - 0.15 12.4 0.1 1.5 9.2 0.1 2.2 2 0 0 2 2 2 0 Transposase HRM PF02793.22 KFM70045.1 - 6.3e-22 77.6 11.8 1.8e-11 44.2 4.3 2.5 2 0 0 2 2 2 2 Hormone receptor domain 7tm_2 PF00002.24 KFM70046.1 - 1.3e-11 44.3 1.5 1.3e-11 44.3 1.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Insulin_TMD PF17870.1 KFM70046.1 - 0.013 15.6 0.3 0.016 15.2 0.3 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DEAD PF00270.29 KFM70047.1 - 0.052 13.3 0.8 0.064 13.0 0.8 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase RNase_HII PF01351.18 KFM70047.1 - 0.057 13.3 1.0 0.092 12.6 1.0 1.3 1 0 0 1 1 1 0 Ribonuclease HII FapA PF03961.13 KFM70047.1 - 0.093 11.3 2.1 0.11 11.1 2.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF16 PF01519.16 KFM70047.1 - 0.21 12.1 6.8 3.6 8.1 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 RasGAP_C PF03836.15 KFM70047.1 - 0.28 11.3 5.1 0.078 13.1 2.1 1.6 2 0 0 2 2 2 0 RasGAP C-terminus Fib_alpha PF08702.10 KFM70047.1 - 0.59 10.3 10.1 0.67 10.1 2.9 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 KFM70047.1 - 7.4 6.9 7.8 1.6 9.0 2.3 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF641 PF04859.12 KFM70047.1 - 8.5 6.7 8.3 14 6.0 0.3 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) BAH PF01426.18 KFM70048.1 - 4.7e-32 110.4 1.2 2e-31 108.4 1.2 1.8 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.24 KFM70048.1 - 1.5e-09 38.4 0.1 2.5e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 ELM2 domain zf-H2C2_2 PF13465.6 KFM70049.1 - 1e-35 120.6 58.9 1.1e-08 35.2 1.5 7.7 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM70049.1 - 1.8e-26 91.1 59.9 1e-05 25.7 4.6 6.3 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-met PF12874.7 KFM70049.1 - 5.4e-24 83.8 50.9 0.00013 22.2 1.3 6.3 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM70049.1 - 2e-19 68.6 55.6 0.00051 20.7 3.5 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM70049.1 - 1.4e-07 31.6 44.7 0.1 12.9 0.2 6.7 5 2 2 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM70049.1 - 1.3e-05 25.1 16.0 0.33 11.0 0.9 5.9 2 2 4 6 6 6 2 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM70049.1 - 5e-05 23.4 22.9 0.001 19.2 6.2 3.0 1 1 2 3 3 3 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_6 PF13912.6 KFM70049.1 - 0.00019 21.3 48.6 0.23 11.5 1.0 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger DUF2256 PF10013.9 KFM70049.1 - 0.0064 16.6 21.8 4.5 7.5 0.1 6.0 6 0 0 6 6 6 2 Uncharacterized protein conserved in bacteria (DUF2256) YyzF PF14116.6 KFM70049.1 - 0.0088 16.0 17.0 22 5.2 0.1 6.0 6 0 0 6 6 6 0 YyzF-like protein zf-C2H2_9 PF16293.5 KFM70049.1 - 0.022 14.6 26.6 6.5 6.7 0.2 6.1 1 1 5 6 6 6 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM70049.1 - 0.033 14.0 9.2 2.5 8.0 0.0 4.9 1 1 5 6 6 6 0 GAGA factor zinc_ribbon_15 PF17032.5 KFM70049.1 - 0.078 13.7 23.4 1.9 9.3 2.0 3.5 1 1 4 5 5 5 0 zinc-ribbon family TRAF6_Z2 PF18048.1 KFM70049.1 - 0.1 12.7 19.2 0.63 10.2 0.4 5.7 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 BolA PF01722.18 KFM70049.1 - 0.13 12.6 7.6 5.3 7.4 1.1 3.6 1 1 2 3 3 3 0 BolA-like protein zf-C2H2_2 PF12756.7 KFM70049.1 - 0.27 11.6 43.2 3.5 8.0 1.1 6.1 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM70049.1 - 0.45 10.5 26.9 0.55 10.2 0.7 6.1 6 0 0 6 6 6 0 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM70049.1 - 0.57 10.2 24.0 1.6 8.7 1.9 4.8 4 1 1 5 5 5 0 Adenylate kinase, active site lid zf-DBF PF07535.12 KFM70049.1 - 0.73 10.0 34.9 6.5 7.0 0.3 6.6 7 0 0 7 7 7 0 DBF zinc finger DUF5330 PF17264.2 KFM70049.1 - 5.2 7.2 11.8 71 3.5 0.1 5.3 7 0 0 7 7 5 0 Family of unknown function (DUF5330) FYVE PF01363.21 KFM70049.1 - 5.7 7.1 31.6 32 4.7 1.4 4.4 1 1 3 4 4 4 0 FYVE zinc finger GTP_EFTU PF00009.27 KFM70050.1 - 1.6e-49 168.1 0.1 2.8e-49 167.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFM70050.1 - 8e-27 93.8 0.3 2.2e-26 92.3 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFM70050.1 - 5.2e-09 36.2 0.2 0.00012 22.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KFM70050.1 - 2.8e-06 27.6 0.1 6e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 KFM70050.1 - 0.0084 16.3 0.5 0.78 10.0 0.1 2.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KFM70050.1 - 0.042 13.4 0.1 8.3 6.0 0.0 3.0 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KFM70050.1 - 0.049 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KFM70050.1 - 0.053 12.4 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase HTH_Tnp_Tc3_2 PF01498.18 KFM70051.1 - 4.2e-16 59.0 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70051.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70051.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70051.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70051.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM70052.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70052.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70052.1 - 1.9e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70052.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70052.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM70053.1 - 5.5e-16 58.6 0.1 5.9e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70053.1 - 8e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM70053.1 - 0.0015 19.1 1.6 0.0015 19.1 1.6 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70053.1 - 0.0026 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70053.1 - 0.016 15.3 0.1 0.066 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM70053.1 - 0.14 12.2 4.0 0.077 13.0 0.8 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM70054.1 - 2.3e-16 59.8 2.2 7.1e-16 58.2 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70054.1 - 1.5e-13 50.7 0.0 3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70054.1 - 3.4e-07 29.9 1.6 8.4e-07 28.6 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70054.1 - 0.0031 17.3 0.5 0.0091 15.8 0.5 1.9 1 0 0 1 1 1 1 Homeodomain-like domain Apolipoprotein PF01442.18 KFM70054.1 - 0.0038 17.1 3.3 0.0075 16.2 3.3 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ABC_tran_CTD PF16326.5 KFM70054.1 - 0.011 16.0 2.6 0.043 14.1 2.2 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain Exonuc_VII_L PF02601.15 KFM70054.1 - 0.011 15.3 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 KFM70054.1 - 0.019 15.1 3.9 0.024 14.7 2.7 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CLZ PF16526.5 KFM70054.1 - 0.021 15.2 0.8 0.074 13.4 0.8 1.9 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 KFM70054.1 - 0.027 14.5 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.6 KFM70054.1 - 0.04 14.3 3.3 0.067 13.5 3.3 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.12 KFM70054.1 - 0.045 13.8 5.2 0.085 12.9 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HSBP1 PF06825.12 KFM70054.1 - 0.066 13.1 0.4 0.51 10.2 0.1 2.1 1 1 1 2 2 2 0 Heat shock factor binding protein 1 FlaC_arch PF05377.11 KFM70054.1 - 0.1 13.0 5.4 0.22 11.9 4.5 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 KFM70054.1 - 0.14 12.7 1.7 0.86 10.1 0.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Zw10 PF06248.13 KFM70054.1 - 0.15 10.6 2.1 0.19 10.2 2.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Tnp_22_trimer PF17489.2 KFM70054.1 - 0.19 11.7 7.6 1.7 8.6 0.7 3.4 1 1 2 3 3 3 0 L1 transposable element trimerization domain DUF16 PF01519.16 KFM70054.1 - 0.63 10.6 4.6 1.2 9.6 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 HTH_Tnp_Tc3_2 PF01498.18 KFM70055.1 - 4.6e-16 58.8 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70055.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70055.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70055.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70055.1 - 1.9 9.2 15.6 0.12 13.0 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain TF_AP-2 PF03299.14 KFM70056.1 - 9.7e-64 215.0 0.0 1.4e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 CABIT PF12736.7 KFM70058.1 - 4e-06 26.3 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, HTH_Tnp_Tc3_2 PF01498.18 KFM70060.1 - 4.1e-16 59.0 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70060.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70060.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70060.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70060.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Retrotrans_gag PF03732.17 KFM70062.1 - 0.00038 20.7 0.6 0.00081 19.6 0.6 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein SCAN PF02023.17 KFM70062.1 - 0.00073 19.3 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 SCAN domain POTRA_TamA_1 PF17243.2 KFM70062.1 - 0.0018 18.3 0.4 0.037 14.1 0.1 2.9 3 0 0 3 3 3 1 POTRA domain TamA domain 1 Coatamer_beta_C PF07718.12 KFM70062.1 - 0.0088 16.0 2.4 0.021 14.8 2.4 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region CelTOS PF18659.1 KFM70062.1 - 0.019 15.4 2.6 0.05 14.0 2.2 2.0 1 1 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites DUF659 PF04937.15 KFM70062.1 - 0.022 14.6 2.1 0.56 10.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) CHASE3 PF05227.13 KFM70062.1 - 0.053 13.4 0.4 0.17 11.8 0.2 2.0 1 1 0 1 1 1 0 CHASE3 domain Nop PF01798.18 KFM70062.1 - 0.25 10.8 7.3 0.032 13.7 2.4 1.8 1 1 1 2 2 2 0 snoRNA binding domain, fibrillarin Epimerase PF01370.21 KFM70064.1 - 1e-20 74.2 0.0 1.3e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM70064.1 - 9.6e-15 54.8 0.0 8e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFM70064.1 - 3.1e-09 36.3 0.0 4.3e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFM70064.1 - 8.1e-09 34.9 0.0 1.3e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFM70064.1 - 8.9e-08 31.6 0.0 6.5e-07 28.8 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFM70064.1 - 5.2e-06 25.8 0.0 8.6e-05 21.8 0.0 2.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KFM70064.1 - 0.021 14.7 0.2 1.3 8.9 0.0 2.6 2 1 1 3 3 3 0 KR domain CENP-B_N PF04218.13 KFM70065.1 - 0.0002 20.9 0.5 0.00054 19.5 0.5 1.8 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 KFM70065.1 - 0.00025 21.0 0.1 0.00093 19.2 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF4371 PF14291.6 KFM70065.1 - 0.00049 19.8 0.3 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-BED PF02892.15 KFM70065.1 - 0.0072 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 BED zinc finger HTH_23 PF13384.6 KFM70065.1 - 0.015 15.1 0.0 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain dsDNA_bind PF01984.20 KFM70065.1 - 0.12 12.6 0.6 4.9 7.5 0.0 2.8 2 0 0 2 2 2 0 Double-stranded DNA-binding domain HTH_28 PF13518.6 KFM70065.1 - 0.16 12.1 0.0 0.5 10.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_45 PF14947.6 KFM70065.1 - 1.3 9.1 3.7 3.8 7.5 0.2 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix TMEM220 PF15071.6 KFM70066.1 - 5.8e-22 78.4 0.3 9.4e-22 77.7 0.3 1.3 1 0 0 1 1 1 1 Transmembrane family 220, helix Tctex-1 PF03645.13 KFM70067.1 - 1.1e-34 118.7 2.9 1.4e-34 118.4 2.9 1.1 1 0 0 1 1 1 1 Tctex-1 family Phasin PF05597.11 KFM70067.1 - 0.017 15.1 1.0 0.023 14.7 1.0 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PP2C PF00481.21 KFM70068.1 - 3.8e-38 131.6 0.1 3.2e-36 125.3 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFM70068.1 - 3.6e-05 23.8 0.1 0.0014 18.5 0.1 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFM70068.1 - 0.00055 19.6 0.0 0.0016 18.2 0.0 1.8 2 1 0 2 2 2 1 Protein phosphatase 2C HALZ PF02183.18 KFM70068.1 - 0.099 12.9 1.7 0.36 11.1 0.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Dymeclin PF09742.9 KFM70069.1 - 4.1e-13 48.6 0.2 4.3e-13 48.6 0.2 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KFM70069.1 - 1.1e-10 40.4 0.2 1.1e-10 40.3 0.2 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Hid1 PF12722.7 KFM70070.1 - 1.9e-244 813.5 6.4 9.4e-195 649.2 2.3 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KFM70070.1 - 8.9e-215 714.8 1.6 1e-214 714.6 1.6 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF4749 PF15936.5 KFM70072.1 - 8.9e-07 29.9 13.2 0.023 15.8 0.9 4.8 1 1 2 4 4 4 4 Domain of unknown function (DUF4749) P2X_receptor PF00864.19 KFM70074.1 - 3.2e-47 161.4 0.4 3.7e-47 161.2 0.4 1.0 1 0 0 1 1 1 1 ATP P2X receptor NodZ PF05830.11 KFM70074.1 - 0.075 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Glyco_hydro_38N PF01074.22 KFM70076.1 - 0.00022 20.7 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38N PF01074.22 KFM70077.1 - 2.5e-20 73.0 0.0 2.7e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 KFM70078.1 - 2.9e-17 62.6 0.0 3.1e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 KFM70079.1 - 1.5e-08 35.0 0.0 1.6e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain CLP1_P PF16575.5 KFM70080.1 - 8.8e-38 130.0 0.3 3.5e-37 128.0 0.0 2.1 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 KFM70080.1 - 0.001 19.0 0.0 0.001 19.0 0.0 2.4 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFM70080.1 - 0.02 14.9 0.0 0.099 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Clp1 PF06807.14 KFM70080.1 - 0.067 13.6 0.5 0.32 11.4 0.0 2.4 2 1 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 RNA_helicase PF00910.22 KFM70080.1 - 0.084 13.3 0.0 0.4 11.1 0.0 2.2 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 KFM70080.1 - 0.093 12.8 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFM70080.1 - 0.15 12.4 0.0 0.48 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain 7tm_1 PF00001.21 KFM70081.1 - 2.4e-09 36.9 0.5 3.4e-09 36.4 0.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-H2C2_2 PF13465.6 KFM70083.1 - 9.4e-56 183.9 75.9 2.9e-09 36.9 2.0 9.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM70083.1 - 2.2e-42 141.2 82.8 1.2e-06 28.6 0.3 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70083.1 - 1.3e-28 97.2 78.2 0.00028 21.4 0.3 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM70083.1 - 1.3e-22 79.4 69.8 0.0013 19.0 0.6 8.3 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM70083.1 - 2.4e-16 59.2 50.9 0.03 14.1 0.5 8.5 8 0 0 8 8 8 7 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM70083.1 - 1.8e-14 53.6 60.1 0.027 14.8 1.2 8.3 7 1 1 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM70083.1 - 2.7e-08 33.6 73.9 0.037 14.0 3.5 9.4 8 2 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM70083.1 - 6.7e-06 25.7 54.3 0.056 13.2 0.4 8.2 8 0 0 8 8 8 4 zinc-finger C2H2-type BolA PF01722.18 KFM70083.1 - 0.00021 21.5 16.8 2.1 8.7 0.3 6.0 1 1 5 6 6 6 2 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM70083.1 - 0.00046 20.2 28.6 0.62 10.2 1.4 7.6 4 2 3 7 7 7 2 Sec23/Sec24 zinc finger DUF2256 PF10013.9 KFM70083.1 - 0.0005 20.1 29.0 7.8 6.7 0.1 7.9 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RRPl_C4 PF17026.5 KFM70083.1 - 0.002 18.2 38.6 0.076 13.1 7.8 4.0 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_9 PF16293.5 KFM70083.1 - 0.0046 16.8 40.5 2.5 8.0 0.2 7.9 2 1 6 8 8 8 3 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM70083.1 - 0.011 15.6 12.1 19 5.2 0.2 5.8 1 1 7 8 8 8 0 GAGA factor zf-DBF PF07535.12 KFM70083.1 - 0.017 15.2 41.5 3.4 7.9 0.1 8.1 8 0 0 8 8 8 0 DBF zinc finger zf-C2H2_2 PF12756.7 KFM70083.1 - 0.023 15.0 65.9 2.9 8.3 1.3 8.0 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) VirE1 PF12189.8 KFM70083.1 - 0.06 13.5 1.2 3.1 8.0 0.1 3.0 3 0 0 3 3 3 0 Single-strand DNA-binding protein zinc_ribbon_15 PF17032.5 KFM70083.1 - 0.061 14.1 37.2 0.67 10.7 2.7 4.2 1 1 1 4 4 4 0 zinc-ribbon family zf-C2HC_2 PF13913.6 KFM70083.1 - 0.2 11.6 41.7 1.7 8.7 0.5 8.2 8 1 0 8 8 7 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFM70083.1 - 0.32 11.1 40.0 11 6.2 0.2 7.7 1 1 4 5 5 5 0 KIAA1045 RING finger zf_UBZ PF18439.1 KFM70083.1 - 0.53 9.9 0.1 0.53 9.9 0.1 7.9 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger DUF2039 PF10217.9 KFM70083.1 - 0.54 10.6 37.7 5.9 7.3 3.5 4.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2039) FYVE PF01363.21 KFM70083.1 - 2.2 8.5 50.2 2.1 8.5 11.7 5.0 1 1 4 5 5 5 0 FYVE zinc finger zf-Dof PF02701.15 KFM70083.1 - 4.2 7.6 27.5 4.1 7.6 0.0 6.8 1 1 6 7 7 6 0 Dof domain, zinc finger Scramblase PF03803.15 KFM70083.1 - 5.1 6.3 8.3 0.72 9.1 1.8 2.3 1 1 2 3 3 3 0 Scramblase C1_1 PF00130.22 KFM70083.1 - 5.1 7.1 53.1 2.5 8.1 3.3 7.1 2 2 5 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF5402 PF17393.2 KFM70083.1 - 7.8 6.5 24.5 9.4 6.2 0.2 6.7 1 1 5 7 7 7 0 Family of unknown function (DUF5402) zf-BED PF02892.15 KFM70083.1 - 9.5 6.3 72.9 0.68 10.0 3.4 8.0 1 1 7 8 8 8 0 BED zinc finger zf-C2H2 PF00096.26 KFM70084.1 - 0.0068 16.8 1.1 0.022 15.2 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM70084.1 - 0.57 10.7 0.2 0.57 10.7 0.2 2.7 3 1 1 4 4 4 0 Zinc-finger double domain SWIM PF04434.17 KFM70085.1 - 0.0016 18.0 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF4760 PF15956.5 KFM70085.1 - 0.022 14.9 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) DDE_3 PF13358.6 KFM70086.1 - 6.3e-16 58.4 0.1 7.1e-15 55.0 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70086.1 - 1.5e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HLH PF00010.26 KFM70088.1 - 7.3e-18 64.3 0.5 1e-17 63.8 0.5 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-UBR PF02207.20 KFM70089.1 - 4.9e-21 74.7 9.6 4.9e-21 74.7 9.6 2.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KFM70089.1 - 2.2e-20 72.2 0.1 6e-20 70.8 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-C3HC4_2 PF13923.6 KFM70089.1 - 0.056 13.3 0.2 0.056 13.3 0.2 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Herpes_UL56 PF04534.12 KFM70089.1 - 0.076 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL56 protein DBINO PF13892.6 KFM70089.1 - 0.15 12.4 4.1 11 6.4 0.0 2.5 2 0 0 2 2 2 0 DNA-binding domain AT_hook PF02178.19 KFM70090.1 - 0.0028 17.3 18.1 0.012 15.4 0.7 3.4 3 0 0 3 3 3 2 AT hook motif zf-H2C2_2 PF13465.6 KFM70091.1 - 4.7e-11 42.6 47.7 3.2e-05 24.1 3.5 7.5 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM70091.1 - 1.2e-10 41.2 71.2 1.3e-05 25.3 3.5 8.6 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70091.1 - 6e-08 32.9 59.5 0.004 17.9 2.0 8.8 8 0 0 8 8 8 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM70091.1 - 3.8e-05 23.4 1.7 3.8e-05 23.4 1.7 6.9 6 1 0 6 6 6 4 C2H2-type zinc-finger domain zf-met PF12874.7 KFM70091.1 - 0.00064 20.0 1.0 0.00064 20.0 1.0 7.1 8 0 0 8 8 8 3 Zinc-finger of C2H2 type DUF1736 PF08409.11 KFM70092.1 - 7.7e-29 99.5 0.1 1.1e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) HTH_Tnp_Tc3_2 PF01498.18 KFM70093.1 - 4.8e-16 58.8 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70093.1 - 1.1e-13 51.2 0.0 2.2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70093.1 - 2e-07 30.7 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70093.1 - 0.0027 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70093.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM70094.1 - 3e-14 53.0 0.0 3.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FF PF01846.19 KFM70098.1 - 1.3e-08 34.9 0.4 2.1e-08 34.2 0.4 1.4 1 0 0 1 1 1 1 FF domain Gemini_AL1_M PF08283.11 KFM70098.1 - 0.0077 16.3 0.5 0.0096 16.0 0.5 1.3 1 1 0 1 1 1 1 Geminivirus rep protein central domain WW PF00397.26 KFM70099.1 - 1e-08 35.1 1.0 2e-08 34.1 1.0 1.5 1 0 0 1 1 1 1 WW domain Mt_ATP-synt_D PF05873.12 KFM70100.1 - 1.3e-54 184.3 7.4 1.4e-54 184.1 7.4 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Plant_NMP1 PF06694.11 KFM70100.1 - 0.12 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Bax1-I PF01027.20 KFM70101.1 - 1.3e-39 136.2 23.4 1.5e-39 136.0 23.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF1772 PF08592.11 KFM70101.1 - 6.2 7.1 7.1 4.8 7.5 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) HNOB PF07700.15 KFM70102.1 - 3.9e-58 196.0 0.3 5.3e-58 195.6 0.3 1.2 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 KFM70102.1 - 3.4e-43 147.6 0.4 1.7e-42 145.4 0.4 2.0 1 1 0 1 1 1 1 Heme NO binding associated HTH_Tnp_Tc3_2 PF01498.18 KFM70103.1 - 1.9e-16 60.1 2.2 5e-16 58.7 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70103.1 - 8.1e-14 51.6 0.0 1.8e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r4_2 PF08281.12 KFM70103.1 - 0.0026 17.4 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sybindin PF04099.12 KFM70104.1 - 0.02 14.9 0.0 0.025 14.5 0.0 1.2 1 1 0 1 1 1 0 Sybindin-like family LRR_8 PF13855.6 KFM70105.1 - 2.5e-15 56.0 4.9 1.3e-06 28.0 0.2 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFM70105.1 - 5.8e-11 42.4 7.9 6.7e-05 23.2 0.6 3.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM70105.1 - 0.0053 16.7 3.8 0.6 10.3 0.1 3.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 KFM70105.1 - 0.19 12.4 7.6 8.9 7.3 1.3 4.9 3 1 1 4 4 4 0 Leucine Rich Repeat CH PF00307.31 KFM70106.1 - 2.4e-09 37.4 0.0 4.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF2070 PF09843.9 KFM70107.1 - 3.1 6.0 7.5 3 6.0 7.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 7tm_1 PF00001.21 KFM70108.1 - 2.6e-22 79.4 0.1 3.6e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM70108.1 - 4.7e-05 22.9 0.2 6.9e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Androgen_recep PF02166.16 KFM70108.1 - 0.047 12.5 1.3 0.076 11.9 1.3 1.2 1 0 0 1 1 1 0 Androgen receptor DUF4602 PF15375.6 KFM70109.1 - 3e-19 69.7 18.0 3.8e-19 69.4 18.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) LNP1 PF15419.6 KFM70109.1 - 0.061 13.6 6.7 0.075 13.3 6.7 1.3 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 TMEMspv1-c74-12 PF11044.8 KFM70109.1 - 4.6 7.3 0.0 4.6 7.3 0.0 3.3 4 0 0 4 4 4 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Phospholip_B PF04916.13 KFM70110.1 - 8.2e-128 427.3 0.1 9.2e-128 427.1 0.1 1.0 1 0 0 1 1 1 1 Phospholipase B DUP PF00674.18 KFM70110.1 - 0.078 13.1 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 DUP family Phospholip_B PF04916.13 KFM70112.1 - 3.6e-127 425.2 0.0 4e-127 425.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase B RhoGAP PF00620.27 KFM70113.1 - 4.1e-49 166.3 0.1 5.5e-49 165.9 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain RhoGEF PF00621.20 KFM70115.1 - 1e-30 107.3 1.0 1.1e-30 107.2 1.0 1.0 1 0 0 1 1 1 1 RhoGEF domain PBC PF03792.13 KFM70118.1 - 1.2e-18 67.5 0.9 1.7e-18 67.1 0.9 1.2 1 0 0 1 1 1 1 PBC domain PBC PF03792.13 KFM70119.1 - 1.4e-60 204.3 0.1 2.1e-60 203.8 0.1 1.3 1 0 0 1 1 1 1 PBC domain Homeodomain PF00046.29 KFM70119.1 - 5.6e-20 71.0 0.8 1.3e-19 69.8 0.8 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM70119.1 - 6.6e-16 57.9 0.0 1.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Nucleoporin_FG2 PF15967.5 KFM70119.1 - 1.7e-05 23.6 0.5 2.8e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeated region YdaS_antitoxin PF15943.5 KFM70119.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KFM70119.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Sec15 PF04091.12 KFM70119.1 - 0.05 13.0 1.4 0.08 12.3 1.4 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like CENP-B_N PF04218.13 KFM70119.1 - 0.073 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF3391 PF11871.8 KFM70119.1 - 0.08 13.5 0.3 0.68 10.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) HTH_23 PF13384.6 KFM70119.1 - 0.11 12.3 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain LZ3wCH PF18517.1 KFM70119.1 - 0.11 12.6 0.0 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 Leucine zipper with capping helix domain HTH_26 PF13443.6 KFM70119.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain NUC130_3NT PF08158.12 KFM70119.1 - 0.25 11.7 1.5 22 5.5 0.1 3.2 3 1 0 3 3 3 0 NUC130/3NT domain Self-incomp_S1 PF05938.11 KFM70120.1 - 0.067 13.7 1.8 0.085 13.4 1.8 1.1 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 MnmE_helical PF12631.7 KFM70121.1 - 0.013 15.7 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 MnmE helical domain CX9C PF16860.5 KFM70122.1 - 1.4e-10 41.0 11.1 1.3e-09 37.9 1.4 2.8 2 1 1 3 3 3 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KFM70122.1 - 6.4e-06 26.2 6.7 0.0002 21.4 2.1 2.5 2 1 0 2 2 2 2 CHCH domain Cmc1 PF08583.10 KFM70122.1 - 0.00095 19.1 11.2 0.093 12.8 1.1 2.5 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NOG1_N PF17835.1 KFM70122.1 - 0.019 14.9 0.0 0.47 10.4 0.0 2.0 1 1 2 3 3 2 0 NOG1 N-terminal helical domain UPF0203 PF05254.12 KFM70122.1 - 0.029 14.6 12.5 0.47 10.7 8.5 3.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.9 KFM70122.1 - 0.031 14.6 10.3 0.69 10.3 5.2 2.7 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 RuBisCO_small PF00101.20 KFM70122.1 - 0.1 12.6 0.9 3.8 7.6 0.1 2.2 1 1 1 2 2 2 0 Ribulose bisphosphate carboxylase, small chain NDUF_B7 PF05676.13 KFM70122.1 - 0.1 12.3 15.9 0.081 12.7 4.8 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.13 KFM70122.1 - 1.1 9.7 9.3 5.2 7.5 0.1 3.1 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) PADR1 PF08063.12 KFM70122.1 - 1.9 8.3 7.5 15 5.5 0.3 3.4 1 1 3 4 4 4 0 PADR1 (NUC008) domain UCR_hinge PF02320.16 KFM70122.1 - 3.1 8.1 13.7 5.2 7.4 2.9 3.2 2 2 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Dimer_Tnp_hAT PF05699.14 KFM70124.1 - 2.6e-11 43.1 0.0 5.9e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KFM70124.1 - 0.0046 16.8 0.4 0.18 11.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) SesA PF17107.5 KFM70124.1 - 0.11 12.7 1.3 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TGT PF01702.18 KFM70124.1 - 0.12 11.5 0.0 0.43 9.7 0.0 1.8 1 1 0 2 2 2 0 Queuine tRNA-ribosyltransferase Propep_M14 PF02244.16 KFM70124.1 - 0.27 11.6 3.0 2.9 8.4 0.7 3.0 3 0 0 3 3 3 0 Carboxypeptidase activation peptide CLIP_SPH_mas PF18398.1 KFM70127.1 - 0.0027 18.1 16.4 0.011 16.1 6.8 2.2 2 0 0 2 2 2 2 Clip-domain serine protease homolog masquerade Tti2 PF10521.9 KFM70129.1 - 0.0012 18.4 0.1 0.0019 17.8 0.1 1.4 1 1 0 1 1 1 1 Tti2 family TIR_2 PF13676.6 KFM70131.1 - 0.00012 22.6 0.0 0.00015 22.4 0.0 1.1 1 0 0 1 1 1 1 TIR domain SOBP PF15279.6 KFM70132.1 - 0.0044 17.7 0.3 0.0044 17.7 0.3 1.1 1 0 0 1 1 1 1 Sine oculis-binding protein OSCP PF00213.18 KFM70133.1 - 9e-43 146.4 0.8 1e-42 146.2 0.8 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit UCH_C PF18031.1 KFM70133.1 - 0.0049 16.8 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases IRS PF02174.17 KFM70134.1 - 1.7e-24 85.6 0.0 3.2e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFM70134.1 - 5.9e-08 33.2 0.0 2e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 PH domain Toxin_31 PF08119.11 KFM70134.1 - 0.0016 18.1 0.2 0.004 16.9 0.2 1.6 1 0 0 1 1 1 1 Scorpion acidic alpha-KTx toxin family DDE_3 PF13358.6 KFM70135.1 - 0.0039 17.0 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease G_glu_transpept PF01019.21 KFM70136.1 - 1.4e-72 245.1 0.0 1.6e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Afaf PF15339.6 KFM70137.1 - 0.0055 16.5 0.0 0.006 16.3 0.0 1.1 1 0 0 1 1 1 1 Acrosome formation-associated factor LRRC37AB_C PF14914.6 KFM70137.1 - 0.036 14.0 0.1 0.043 13.7 0.1 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Cortexin PF11057.8 KFM70137.1 - 0.052 13.4 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Cortexin of kidney Synaptobrevin PF00957.21 KFM70137.1 - 0.13 12.0 1.2 0.17 11.7 1.2 1.1 1 0 0 1 1 1 0 Synaptobrevin Neurensin PF14927.6 KFM70137.1 - 0.17 11.6 0.6 0.24 11.1 0.4 1.4 1 1 0 1 1 1 0 Neurensin Insulin_TMD PF17870.1 KFM70137.1 - 1.5 8.9 9.0 2.4 8.3 5.5 2.1 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment SET PF00856.28 KFM70139.1 - 7.4e-08 33.0 0.1 7.4e-08 33.0 0.1 2.4 2 1 0 2 2 2 1 SET domain HTH_Tnp_Tc3_2 PF01498.18 KFM70140.1 - 2.4e-16 59.7 2.2 6.9e-16 58.3 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70140.1 - 1.6e-13 50.6 0.0 2.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70140.1 - 2.8e-07 30.2 1.6 8.3e-07 28.7 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70140.1 - 0.0031 17.3 0.5 0.0089 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70140.1 - 6.8 7.4 17.8 0.15 12.7 2.0 3.6 3 1 1 4 4 4 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM70141.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70141.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70141.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70141.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70141.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Castor1_N PF18700.1 KFM70143.1 - 0.11 12.3 0.1 10 6.1 0.0 2.1 1 1 1 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain fn3_4 PF16794.5 KFM70146.1 - 7.2e-34 115.8 0.0 1.2e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-III type domain fn3 PF00041.21 KFM70146.1 - 0.00045 20.5 0.0 0.00086 19.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Laminin_EGF PF00053.24 KFM70147.1 - 0.0024 18.0 4.6 0.0024 18.0 4.6 4.3 4 0 0 4 4 4 3 Laminin EGF domain Exo_endo_phos_2 PF14529.6 KFM70149.1 - 0.00016 21.5 0.1 0.00073 19.4 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DEAD PF00270.29 KFM70150.1 - 1.1e-46 158.8 3.0 1.9e-46 158.0 0.1 2.7 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM70150.1 - 2.9e-32 111.3 0.4 3.5e-30 104.6 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM70150.1 - 2e-07 31.2 0.0 2e-07 31.2 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KFM70150.1 - 0.064 13.6 0.1 0.92 9.9 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_12 PF13087.6 KFM70150.1 - 0.07 12.7 0.2 0.07 12.7 0.2 2.5 3 0 0 3 3 3 0 AAA domain BIV_Env PF05858.12 KFM70150.1 - 0.11 10.6 0.2 0.33 9.1 0.1 1.7 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) MCR_C PF04609.12 KFM70150.1 - 0.35 9.9 8.4 1.7 7.7 0.5 3.4 2 1 1 3 3 3 0 Methyl-coenzyme M reductase operon protein C AAA_22 PF13401.6 KFM70150.1 - 0.41 10.9 3.2 0.9 9.8 1.0 2.7 2 1 0 2 2 2 0 AAA domain Curto_V2 PF07325.11 KFM70150.1 - 5.7 6.8 8.1 2.8 7.8 1.4 2.9 3 0 0 3 3 3 0 Curtovirus V2 protein Pkinase PF00069.25 KFM70151.1 - 1.9e-05 24.2 0.0 1.9e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM70151.1 - 0.024 13.9 0.0 0.027 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase GST_C_3 PF14497.6 KFM70153.1 - 2.8e-14 53.1 0.0 4.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM70153.1 - 2e-08 34.4 0.0 2.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM70153.1 - 0.00012 22.4 0.0 0.00032 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFM70153.1 - 0.00026 21.3 0.0 0.00066 20.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFM70153.1 - 0.0078 16.2 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GABP-alpha PF11620.8 KFM70153.1 - 0.014 15.6 0.1 0.024 14.8 0.1 1.4 1 0 0 1 1 1 0 GA-binding protein alpha chain UMP1 PF05348.11 KFM70154.1 - 3.7e-23 82.0 0.0 4.5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Solute_trans_a PF03619.16 KFM70155.1 - 2.6e-95 318.9 17.2 3.7e-95 318.4 17.2 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Senescence PF06911.12 KFM70156.1 - 6.8e-44 150.4 1.0 1.1e-43 149.7 1.0 1.3 1 0 0 1 1 1 1 Senescence-associated protein TPR_1 PF00515.28 KFM70156.1 - 0.014 15.2 0.6 0.033 14.0 0.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HrcA PF01628.21 KFM70156.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 HrcA protein C terminal domain Methyltransf_11 PF08241.12 KFM70157.1 - 7.8e-20 71.3 0.0 1.4e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM70157.1 - 4.7e-16 59.3 0.0 7.9e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM70157.1 - 3.8e-11 43.0 0.0 8.2e-11 41.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM70157.1 - 1.2e-08 35.6 0.0 3.2e-08 34.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM70157.1 - 7.2e-08 32.0 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFM70157.1 - 2.2e-05 24.3 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KFM70157.1 - 7.9e-05 21.4 0.0 0.00011 21.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KFM70157.1 - 0.00048 19.7 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KFM70157.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KFM70157.1 - 0.0035 16.9 0.3 0.0063 16.1 0.0 1.6 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 KFM70157.1 - 0.0045 17.0 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFM70157.1 - 0.0063 15.8 0.0 0.0076 15.6 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KFM70157.1 - 0.0084 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_8 PF05148.15 KFM70157.1 - 0.017 15.0 0.1 0.052 13.4 0.1 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_4 PF02390.17 KFM70157.1 - 0.019 14.4 0.1 0.038 13.4 0.1 1.6 1 1 0 1 1 1 0 Putative methyltransferase tRNA_U5-meth_tr PF05958.11 KFM70157.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 KFM70157.1 - 0.036 13.5 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB NodS PF05401.11 KFM70157.1 - 0.038 13.6 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.12 KFM70157.1 - 0.072 12.2 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.13 KFM70157.1 - 0.097 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KFM70157.1 - 0.14 12.0 0.0 2.4 7.9 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF938) SF3A3 PF16837.5 KFM70157.1 - 0.17 12.4 2.2 0.41 11.2 2.2 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Solute_trans_a PF03619.16 KFM70158.1 - 1.2e-51 175.8 3.8 1.4e-51 175.6 3.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Solute_trans_a PF03619.16 KFM70159.1 - 8.7e-10 38.6 0.4 1.2e-09 38.0 0.4 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2584 PF10763.9 KFM70160.1 - 0.081 13.1 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) Het-C PF07217.11 KFM70160.1 - 0.1 11.1 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C HTH_Tnp_Tc3_2 PF01498.18 KFM70161.1 - 3.3e-11 43.3 4.3 3.7e-11 43.1 2.4 2.0 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM70161.1 - 1.3e-05 25.7 1.9 1.3e-05 25.7 1.9 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 KFM70161.1 - 2.8e-05 23.8 2.2 0.00017 21.3 0.0 3.0 2 2 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70161.1 - 0.0011 18.7 1.5 0.019 14.7 0.3 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_12 PF08461.10 KFM70161.1 - 0.0017 18.3 0.1 0.0039 17.1 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_33 PF13592.6 KFM70161.1 - 0.017 14.8 0.0 0.05 13.2 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.6 KFM70161.1 - 0.033 13.7 0.2 0.19 11.3 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KFM70161.1 - 0.044 13.8 1.5 0.13 12.2 0.0 2.4 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain SecA_SW PF07516.13 KFM70161.1 - 0.097 12.7 0.3 0.12 12.5 0.3 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain DDE_3 PF13358.6 KFM70162.1 - 1.9e-12 47.1 0.0 2.9e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70162.1 - 5.7e-07 29.7 1.6 1.3e-06 28.6 1.6 1.6 1 0 0 1 1 1 1 Transposase AF-4 PF05110.13 KFM70163.1 - 4e-09 35.2 44.3 1.5e-05 23.4 0.0 3.1 2 2 0 3 3 3 2 AF-4 proto-oncoprotein HTH_Tnp_Tc3_2 PF01498.18 KFM70164.1 - 7.6e-15 54.9 1.8 1.5e-14 53.9 1.8 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70164.1 - 3.6e-13 49.5 0.0 6.1e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM70164.1 - 0.00025 21.6 6.1 0.0079 16.8 0.9 2.9 3 0 0 3 3 3 2 Homeodomain-like domain MarR_2 PF12802.7 KFM70164.1 - 0.0041 17.0 0.6 0.22 11.4 0.0 2.6 2 1 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM70164.1 - 0.011 15.7 0.9 0.042 13.8 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain FAM176 PF14851.6 KFM70165.1 - 0.01 15.5 2.0 0.012 15.3 0.2 1.7 1 1 1 2 2 2 0 FAM176 family Ctr PF04145.15 KFM70165.1 - 1.4 9.6 5.1 4.1 8.0 5.1 1.8 1 1 0 1 1 1 0 Ctr copper transporter family DAGAT PF03982.13 KFM70166.1 - 5.1e-115 383.5 0.0 6e-115 383.2 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Torus PF16131.5 KFM70167.1 - 0.08 13.7 0.2 0.12 13.1 0.2 1.3 1 0 0 1 1 1 0 Torus domain HTH_Tnp_Tc3_2 PF01498.18 KFM70169.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70169.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease ASC PF00858.24 KFM70170.1 - 5.5e-13 48.7 0.3 6.4e-13 48.5 0.3 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel PIF1 PF05970.14 KFM70171.1 - 5.3e-19 68.6 0.0 6.7e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase KAP_NTPase PF07693.14 KFM70171.1 - 1.5e-05 24.4 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 KFM70171.1 - 0.0012 19.3 0.0 0.0021 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2791 PF10923.8 KFM70171.1 - 0.018 13.9 0.1 0.035 13.0 0.1 1.4 1 1 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AFG1_ATPase PF03969.16 KFM70171.1 - 0.038 12.9 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_30 PF13604.6 KFM70171.1 - 0.044 13.5 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 KFM70171.1 - 0.075 13.1 0.3 0.23 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Hira PF07569.11 KFM70175.1 - 3.1e-32 112.1 0.0 3.8e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 TUP1-like enhancer of split HIRA_B PF09453.10 KFM70176.1 - 1.1e-06 28.4 0.0 3.1e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 HIRA B motif AMP-binding PF00501.28 KFM70176.1 - 0.044 12.4 0.2 0.12 11.0 0.4 1.6 2 0 0 2 2 2 0 AMP-binding enzyme TFIIA PF03153.13 KFM70176.1 - 0.51 10.3 11.9 0.65 9.9 11.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0302 PF08864.10 KFM70177.1 - 0.0028 17.7 0.1 0.0052 16.8 0.1 1.4 1 0 0 1 1 1 1 UPF0302 domain Metallophos PF00149.28 KFM70178.1 - 6e-41 141.2 0.2 7.6e-41 140.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFM70178.1 - 1.6e-23 82.8 2.2 2.3e-23 82.4 1.3 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain VWA PF00092.28 KFM70180.1 - 2.2e-35 122.5 0.1 2.9e-35 122.1 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFM70180.1 - 1.9e-13 51.0 0.1 3.4e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ephrin_rec_like PF07699.13 KFM70180.1 - 6.5e-07 29.0 8.9 2.7e-06 27.1 8.9 2.2 1 0 0 1 1 1 1 Putative ephrin-receptor like Sushi PF00084.20 KFM70180.1 - 3.2e-06 27.6 0.7 3.2e-06 27.6 0.7 2.8 4 0 0 4 4 3 1 Sushi repeat (SCR repeat) VWA_3 PF13768.6 KFM70180.1 - 0.00061 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFM70180.1 - 0.0023 17.4 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 KFM70180.1 - 0.027 13.7 0.1 0.16 11.2 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1194) SMC_Nse1 PF07574.13 KFM70180.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex PH_11 PF15413.6 KFM70180.1 - 0.22 12.0 0.2 0.79 10.2 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain D_CNTX PF17492.2 KFM70180.1 - 0.37 11.0 24.7 0.04 14.1 17.3 2.6 2 0 0 2 2 2 0 Delta Ctenitoxins EGF_MSP1_1 PF12946.7 KFM70180.1 - 4.9 7.3 20.0 0.15 12.1 0.6 3.1 3 0 0 3 3 3 0 MSP1 EGF domain 1 HTH_Tnp_Tc3_2 PF01498.18 KFM70181.1 - 2.5e-16 59.7 2.2 6.7e-16 58.3 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70181.1 - 1.7e-13 50.6 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70181.1 - 3.5e-07 29.9 1.6 8.1e-07 28.7 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70181.1 - 0.0033 17.2 0.5 0.0087 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70181.1 - 3.2 8.4 15.6 0.14 12.7 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RVT_1 PF00078.27 KFM70182.1 - 0.027 14.0 0.0 0.027 14.0 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ShK PF01549.24 KFM70184.1 - 1.2 9.7 5.1 7.5 7.2 1.7 2.5 2 0 0 2 2 2 0 ShK domain-like UPF0061 PF02696.14 KFM70186.1 - 0.059 12.1 0.2 0.064 12.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family WD40 PF00400.32 KFM70187.1 - 7.3e-47 156.4 12.3 8.6e-07 29.6 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM70187.1 - 8.3e-12 45.3 0.1 0.29 11.5 0.0 5.6 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM70187.1 - 1.2e-07 31.0 0.2 0.036 13.0 0.0 4.0 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFM70187.1 - 9.8e-06 25.4 0.4 3.3 7.8 0.0 3.7 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KFM70187.1 - 0.15 12.0 0.0 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat PX PF00787.24 KFM70189.1 - 4e-11 42.9 0.0 1.3e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 PX domain SL4P PF17618.2 KFM70189.1 - 0.0055 16.7 0.2 0.018 15.1 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized Strongylid L4 protein HAD_2 PF13419.6 KFM70190.1 - 2e-15 57.4 0.0 3.5e-15 56.5 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM70190.1 - 2.9e-14 53.9 0.0 3.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM70190.1 - 2.2e-07 30.8 0.0 5.3e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Acyl_transf_3 PF01757.22 KFM70191.1 - 9e-23 80.9 48.6 9e-23 80.9 48.6 1.5 2 0 0 2 2 2 1 Acyltransferase family DUF5344 PF17279.2 KFM70192.1 - 0.0011 19.5 1.9 0.029 14.9 0.3 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5344) zf-C4H2 PF10146.9 KFM70192.1 - 0.004 17.5 1.3 0.005 17.2 1.3 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein CREPT PF16566.5 KFM70192.1 - 0.032 14.4 4.4 0.026 14.7 2.5 1.8 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour VPS28 PF03997.12 KFM70192.1 - 0.12 12.1 1.4 0.28 10.8 1.4 1.6 1 1 0 1 1 1 0 VPS28 protein T4SS PF07996.11 KFM70192.1 - 0.16 12.4 2.3 1.3 9.4 0.8 2.0 1 1 1 2 2 2 0 Type IV secretion system proteins YlqD PF11068.8 KFM70192.1 - 0.64 10.4 2.8 0.44 10.9 1.3 1.6 1 1 1 2 2 2 0 YlqD protein zf-C2HC PF01530.18 KFM70193.1 - 4.9e-15 55.4 9.8 1.1e-14 54.3 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C2HC type MYT1 PF08474.11 KFM70193.1 - 0.023 14.6 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 Myelin transcription factor 1 Retrotran_gag_2 PF14223.6 KFM70195.1 - 7.8e-07 28.8 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Cullin PF00888.22 KFM70196.1 - 1.1e-51 176.3 4.9 1.3e-51 176.0 4.9 1.0 1 0 0 1 1 1 1 Cullin family GA-like PF17573.2 KFM70196.1 - 0.096 12.6 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 GA-like domain RtcB PF01139.17 KFM70197.1 - 1.1e-141 472.8 0.2 1.2e-141 472.6 0.2 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Ca_chan_IQ PF08763.11 KFM70198.1 - 9.6e-31 105.8 0.0 1.9e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KFM70198.1 - 2e-28 97.9 0.1 4.6e-28 96.7 0.1 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ion_trans PF00520.31 KFM70198.1 - 2.5e-27 95.7 1.3 3.5e-27 95.2 1.3 1.2 1 0 0 1 1 1 1 Ion transport protein CAC1F_C PF16885.5 KFM70198.1 - 1.1e-14 55.0 3.4 6e-09 36.0 0.0 2.4 2 1 0 2 2 2 2 Voltage-gated calcium channel subunit alpha, C-term PKD_channel PF08016.12 KFM70198.1 - 0.081 11.6 0.2 0.12 11.1 0.2 1.2 1 0 0 1 1 1 0 Polycystin cation channel EF-hand_11 PF08976.11 KFM70198.1 - 0.087 13.7 0.0 0.34 11.8 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Ion_trans PF00520.31 KFM70199.1 - 6.6e-24 84.5 5.1 6.6e-24 84.5 5.1 1.9 2 0 0 2 2 2 1 Ion transport protein DHHC PF01529.20 KFM70199.1 - 0.22 11.6 4.4 0.6 10.2 2.4 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase SUR7 PF06687.12 KFM70199.1 - 0.35 10.5 3.8 0.39 10.3 3.6 1.4 1 1 0 1 1 1 0 SUR7/PalI family DUF1676 PF07898.13 KFM70200.1 - 0.16 12.0 5.6 0.22 11.6 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Ion_trans PF00520.31 KFM70203.1 - 2.8e-25 89.0 4.0 3e-25 88.9 4.0 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM70203.1 - 1.2e-05 24.3 1.2 1.5e-05 23.9 1.2 1.2 1 0 0 1 1 1 1 Polycystin cation channel MRVI1 PF05781.12 KFM70203.1 - 0.089 11.5 0.1 0.1 11.3 0.1 1.0 1 0 0 1 1 1 0 MRVI1 protein DUF3989 PF13150.6 KFM70204.1 - 0.018 14.7 0.1 0.021 14.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Ion_trans PF00520.31 KFM70205.1 - 5.2e-19 68.4 0.0 5.2e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM70205.1 - 0.011 14.5 0.3 0.012 14.3 0.3 1.0 1 0 0 1 1 1 0 Polycystin cation channel Sigma_reg_N PF13800.6 KFM70205.1 - 0.056 13.7 0.2 0.074 13.4 0.2 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal HTH_Tnp_Tc3_2 PF01498.18 KFM70207.1 - 4.6e-16 58.8 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70207.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70207.1 - 2e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70207.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70207.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain KCNQ2_u3 PF16642.5 KFM70208.1 - 3.1 8.9 9.6 15 6.7 6.2 2.2 1 1 1 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 DDE_3 PF13358.6 KFM70209.1 - 5.3e-16 58.7 0.1 6.1e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70209.1 - 7.2e-16 58.2 6.5 1.5e-15 57.2 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM70209.1 - 0.0011 19.5 1.6 0.0011 19.5 1.6 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70209.1 - 0.0014 18.4 0.1 0.063 13.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM70209.1 - 0.0058 16.6 0.4 0.0058 16.6 0.4 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 KFM70209.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KFM70210.1 - 3.2e-16 59.3 3.4 5.3e-16 58.6 2.2 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70210.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70210.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70210.1 - 0.0011 18.7 1.2 0.0071 16.1 0.6 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70210.1 - 1.7 9.3 15.6 0.11 13.1 1.9 3.3 2 1 1 3 3 3 0 Homeodomain-like domain Ig_3 PF13927.6 KFM70211.1 - 2e-07 31.5 0.0 3e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM70211.1 - 6.3e-06 26.2 0.0 1.5e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM70211.1 - 0.00069 19.9 0.0 0.001 19.4 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM70211.1 - 0.00095 19.2 0.1 0.0013 18.8 0.1 1.5 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM70212.1 - 2.3e-16 59.8 2.2 4.9e-16 58.7 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70212.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70213.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70213.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM70214.1 - 3.9e-09 36.4 0.0 4.5e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HR1 PF02185.16 KFM70215.1 - 0.0005 20.1 2.2 0.00084 19.4 2.2 1.4 1 0 0 1 1 1 1 Hr1 repeat Fez1 PF06818.15 KFM70215.1 - 0.0045 17.5 3.6 0.0047 17.4 3.6 1.0 1 0 0 1 1 1 1 Fez1 SlyX PF04102.12 KFM70215.1 - 0.016 15.8 1.9 0.12 13.0 1.6 2.0 1 1 1 2 2 2 0 SlyX Cnn_1N PF07989.11 KFM70215.1 - 0.02 15.0 4.9 0.033 14.3 1.9 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 MT PF12777.7 KFM70215.1 - 0.021 13.9 0.6 0.023 13.8 0.6 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor USP8_interact PF08941.10 KFM70215.1 - 0.15 11.8 2.1 0.18 11.6 2.1 1.1 1 0 0 1 1 1 0 USP8 interacting Lectin_C PF00059.21 KFM70216.1 - 3.7e-12 46.9 1.3 2.1e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 KFM70216.1 - 0.023 14.6 9.6 0.14 12.1 9.6 2.2 1 1 0 1 1 1 0 PAN domain Ferritin PF00210.24 KFM70218.1 - 5.2e-25 88.0 5.1 6e-25 87.8 5.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KFM70218.1 - 0.0001 22.7 1.5 0.00016 22.1 1.5 1.3 1 0 0 1 1 1 1 Rubrerythrin DUF2811 PF10929.8 KFM70218.1 - 0.024 14.9 0.1 0.054 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) ACOX PF01756.19 KFM70218.1 - 0.025 14.2 0.6 0.061 12.9 0.1 1.7 2 0 0 2 2 2 0 Acyl-CoA oxidase Rhomboid_N PF12122.8 KFM70218.1 - 0.034 14.3 0.0 0.12 12.6 0.0 2.1 1 1 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease Shikimate_dh_N PF08501.11 KFM70218.1 - 0.099 12.9 0.1 0.23 11.8 0.1 1.8 1 1 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain Carboxyl_trans PF01039.22 KFM70219.1 - 8.9e-62 209.3 0.6 1e-61 209.1 0.6 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Actin PF00022.19 KFM70219.1 - 0.00071 18.3 0.1 0.0017 17.1 0.0 1.5 1 1 1 2 2 2 1 Actin Carboxyl_trans PF01039.22 KFM70220.1 - 1.4e-38 132.8 0.0 1.7e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KFM70220.1 - 0.16 11.4 0.4 0.22 11.0 0.4 1.2 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) Collagen PF01391.18 KFM70222.1 - 9e-17 60.6 68.5 5.5e-07 29.2 21.9 3.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) PINIT PF14324.6 KFM70226.1 - 3.7e-32 111.7 2.8 7.4e-32 110.7 0.6 2.3 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.20 KFM70226.1 - 5.3e-20 70.9 4.6 1e-19 70.0 4.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFM70226.1 - 0.0017 18.1 1.9 0.0043 16.8 1.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KFM70226.1 - 0.0041 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 SAP domain PHD PF00628.29 KFM70226.1 - 0.93 9.4 3.1 2.5 8.1 3.1 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.25 KFM70226.1 - 2.6 8.0 5.7 5.8 6.9 5.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH_13 PF16652.5 KFM70227.1 - 0.00018 21.4 0.4 0.00022 21.1 0.4 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFM70227.1 - 0.0039 17.7 0.2 0.0064 17.0 0.1 1.5 1 1 0 1 1 1 1 PH domain DDE_3 PF13358.6 KFM70229.1 - 1e-15 57.8 0.0 1.5e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70229.1 - 1.7e-07 31.4 0.1 3.9e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Transposase SDF PF00375.18 KFM70230.1 - 2e-36 125.9 11.0 2.2e-36 125.7 11.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Otopetrin PF03189.13 KFM70231.1 - 2.4e-158 527.6 20.6 3.1e-158 527.2 20.6 1.1 1 0 0 1 1 1 1 Otopetrin S1FA PF04689.13 KFM70231.1 - 0.22 11.7 0.6 1.9 8.7 0.8 2.5 2 0 0 2 2 2 0 DNA binding protein S1FA SOCS_box PF07525.16 KFM70232.1 - 8.5e-11 42.0 2.8 8.5e-11 42.0 2.8 2.6 2 0 0 2 2 2 1 SOCS box zf-RanBP PF00641.18 KFM70233.1 - 0.0024 17.2 3.2 0.0084 15.4 3.2 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Na_Ca_ex_C PF16494.5 KFM70233.1 - 0.17 12.3 2.8 0.37 11.3 2.8 1.5 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain PH_13 PF16652.5 KFM70234.1 - 1.4e-52 177.7 4.0 2.4e-52 176.9 4.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KFM70234.1 - 3.4e-27 95.9 1.2 3.4e-27 95.9 1.2 2.0 2 0 0 2 2 2 1 RhoGEF domain C2 PF00168.30 KFM70234.1 - 2.7e-25 88.6 0.1 7.5e-25 87.2 0.0 1.7 2 0 0 2 2 2 1 C2 domain PH_16 PF17838.1 KFM70234.1 - 4.7e-05 23.2 0.4 8.1e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 PH domain PH PF00169.29 KFM70234.1 - 0.00075 20.0 0.5 0.0024 18.3 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_5 PF15405.6 KFM70234.1 - 0.3 11.2 2.7 2.8 8.0 2.7 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain SH3_9 PF14604.6 KFM70235.1 - 6.2e-66 218.1 7.5 5.7e-16 58.1 0.1 5.5 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.28 KFM70235.1 - 9.6e-59 194.8 14.2 1.9e-14 53.0 0.0 5.9 5 1 1 6 6 6 5 SH3 domain SH3_2 PF07653.17 KFM70235.1 - 6.9e-54 179.4 9.5 5e-12 45.3 0.0 6.1 5 1 1 6 6 6 5 Variant SH3 domain EF-hand_4 PF12763.7 KFM70235.1 - 1.9e-31 108.1 0.0 3.9e-14 52.5 0.0 3.0 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFM70235.1 - 1.7e-10 39.6 0.0 0.0016 17.9 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFM70235.1 - 4.1e-09 35.6 0.1 0.14 12.1 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KFM70235.1 - 8.1e-08 32.6 0.0 0.00087 19.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFM70235.1 - 0.0072 16.1 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair DUF1664 PF07889.12 KFM70235.1 - 0.0073 16.3 16.7 0.17 11.9 6.1 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) LPP PF04728.13 KFM70235.1 - 0.019 15.3 6.5 1 9.8 0.1 3.6 2 1 1 3 3 3 0 Lipoprotein leucine-zipper EF-hand_5 PF13202.6 KFM70235.1 - 0.021 14.3 0.1 2.4 7.8 0.0 2.7 2 0 0 2 2 2 0 EF hand NPV_P10 PF05531.12 KFM70235.1 - 2.6 8.6 16.9 5.1 7.6 3.2 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 KFM70235.1 - 6.4 5.5 53.0 10 4.9 53.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 KFM70235.1 - 9.9 6.7 18.7 2.1 8.8 1.6 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) UCH PF00443.29 KFM70236.1 - 2e-31 109.5 31.0 3.5e-30 105.3 31.0 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFM70236.1 - 1.3e-15 57.4 6.6 1.3e-15 57.4 6.6 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Arm PF00514.23 KFM70237.1 - 6.7e-06 26.0 0.1 0.021 14.8 0.0 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 KFM70237.1 - 1.1e-05 24.9 0.5 1.3e-05 24.6 0.5 1.1 1 0 0 1 1 1 1 V-ATPase subunit H Cnd1 PF12717.7 KFM70237.1 - 8.8e-05 22.6 0.1 0.00012 22.1 0.1 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFM70237.1 - 0.00011 22.1 0.1 0.23 11.8 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KFM70237.1 - 0.00068 20.0 0.0 0.0012 19.1 0.0 1.5 1 1 0 1 1 1 1 HEAT repeats MMS19_C PF12460.8 KFM70237.1 - 0.0017 17.5 0.2 0.0031 16.7 0.1 1.5 1 1 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 KFM70237.1 - 0.0022 18.5 0.2 0.64 10.6 0.0 2.8 2 1 1 3 3 3 2 HEAT-like repeat TPR_1 PF00515.28 KFM70237.1 - 0.0083 15.9 0.1 0.03 14.2 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat V-ATPase_H_C PF11698.8 KFM70237.1 - 0.0092 16.1 0.3 0.09 12.9 0.0 2.1 1 1 1 2 2 2 1 V-ATPase subunit H TPR_8 PF13181.6 KFM70237.1 - 0.012 15.8 0.6 0.11 12.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Rcd1 PF04078.13 KFM70237.1 - 0.027 13.8 0.1 1.8 7.8 0.0 2.1 1 1 1 2 2 2 0 Cell differentiation family, Rcd1-like Sec7_N PF12783.7 KFM70237.1 - 0.029 14.3 0.3 2.3 8.1 0.0 2.1 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_2 PF07719.17 KFM70237.1 - 0.097 12.8 0.3 2 8.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RT_RNaseH PF17917.1 KFM70238.1 - 2.7e-05 24.4 0.2 8.7e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KFM70238.1 - 9.5e-05 22.6 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain IL2 PF00715.17 KFM70238.1 - 0.048 13.6 0.2 0.16 11.9 0.2 1.9 1 0 0 1 1 1 0 Interleukin 2 EMP24_GP25L PF01105.24 KFM70239.1 - 3.7e-53 180.2 0.1 4.5e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF658 PF04936.12 KFM70239.1 - 0.089 12.5 0.0 0.17 11.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF658) SdrD_B PF17210.3 KFM70239.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 SdrD B-like domain Rab5-bind PF09311.11 KFM70241.1 - 0.00062 19.2 13.7 0.00062 19.2 13.7 3.8 1 1 3 4 4 4 1 Rabaptin-like protein DUF4407 PF14362.6 KFM70241.1 - 0.00063 19.2 9.8 0.00063 19.2 9.8 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4407) DUF5082 PF16888.5 KFM70241.1 - 0.0042 17.4 20.8 0.0042 17.4 20.8 4.1 1 1 3 4 4 4 1 Domain of unknown function (DUF5082) SF-assemblin PF06705.11 KFM70241.1 - 0.0051 16.2 57.4 0.012 15.0 11.7 3.3 1 1 2 3 3 3 3 SF-assemblin/beta giardin NRho PF16733.5 KFM70241.1 - 0.066 13.3 1.0 25 5.0 0.0 3.5 3 0 0 3 3 3 0 Rhomboid N-terminal domain ZYG-11_interact PF05884.12 KFM70241.1 - 6 6.2 16.7 1.5 8.2 1.2 3.0 2 1 1 3 3 3 0 Interactor of ZYG-11 Baculo_PEP_C PF04513.12 KFM70241.1 - 9.4 6.3 20.9 1.1 9.2 3.7 5.0 3 1 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KFM70242.1 - 0.0014 19.0 0.4 0.0066 16.8 0.1 2.0 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) APG6_N PF17675.1 KFM70242.1 - 0.044 14.3 8.2 0.062 13.8 8.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-Q PF13094.6 KFM70242.1 - 0.048 13.9 8.3 0.025 14.8 6.4 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit GIT_CC PF16559.5 KFM70242.1 - 0.11 12.4 2.4 0.21 11.5 2.4 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Bap31_Bap29_C PF18035.1 KFM70242.1 - 0.11 12.5 7.3 0.27 11.3 2.6 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 KFM70242.1 - 0.13 11.6 1.6 0.14 11.5 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.6 KFM70242.1 - 0.28 11.3 9.6 0.11 12.6 6.0 2.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 PilO PF04350.13 KFM70242.1 - 0.31 11.2 3.9 0.38 10.9 3.0 1.6 1 1 1 2 2 2 0 Pilus assembly protein, PilO DUF4250 PF14056.6 KFM70243.1 - 0.00023 21.0 3.9 0.0011 18.9 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4250) NYD-SP28 PF14772.6 KFM70243.1 - 0.023 14.7 15.5 0.019 15.0 13.6 1.9 1 1 0 1 1 1 0 Sperm tail FliD_N PF02465.18 KFM70243.1 - 0.073 13.8 3.7 0.088 13.5 2.8 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus 60KD_IMP PF02096.20 KFM70243.1 - 0.081 12.8 1.2 0.13 12.1 1.2 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Phasin PF05597.11 KFM70243.1 - 0.083 12.9 6.7 0.32 11.0 1.6 2.4 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TcpS PF17456.2 KFM70243.1 - 0.13 12.3 6.9 0.09 12.8 5.2 1.5 1 1 0 1 1 1 0 Toxin-coregulated pilus protein S SKA2 PF16740.5 KFM70243.1 - 0.19 11.5 14.1 2 8.3 13.2 2.8 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 FUSC PF04632.12 KFM70243.1 - 1.1 7.7 4.3 1.1 7.7 4.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin_2 PF14523.6 KFM70243.1 - 1.9 8.9 17.2 0.69 10.3 11.2 2.3 1 1 1 2 2 2 0 Syntaxin-like protein NPV_P10 PF05531.12 KFM70243.1 - 1.9 9.0 7.5 0.56 10.7 0.9 2.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein ACCA PF03255.14 KFM70243.1 - 4.9 7.0 9.4 20 5.0 9.4 2.1 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4337 PF14235.6 KFM70243.1 - 9.7 6.3 12.1 1.3 9.1 7.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DNTTIP1_dimer PF18192.1 KFM70244.1 - 1.1e-27 96.1 1.0 2e-27 95.3 1.0 1.4 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain AT_hook PF02178.19 KFM70244.1 - 9 6.5 10.5 1.9 8.6 1.2 2.9 2 0 0 2 2 2 0 AT hook motif CAP PF00188.26 KFM70245.1 - 7e-20 72.1 2.0 7e-20 72.1 2.0 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family WD40 PF00400.32 KFM70246.1 - 7e-27 93.2 25.4 8e-06 26.5 0.1 10.6 11 0 0 11 11 11 7 WD domain, G-beta repeat BBS2_Mid PF14783.6 KFM70246.1 - 0.072 13.1 0.1 14 5.8 0.0 3.7 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 KFM70246.1 - 0.29 11.8 1.7 8.1 7.1 0.0 3.8 4 1 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella dsrm PF00035.26 KFM70247.1 - 6e-34 116.6 0.5 2.6e-15 56.8 0.1 3.3 3 0 0 3 3 3 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFM70247.1 - 9.3e-16 57.9 4.9 4.7e-08 33.2 0.1 3.5 3 2 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 Staufen_C PF16482.5 KFM70247.1 - 0.00082 19.5 0.4 0.037 14.2 0.0 3.0 3 1 0 3 3 3 1 Staufen C-terminal domain LPP20 PF02169.16 KFM70247.1 - 0.013 15.8 5.1 0.09 13.1 0.4 2.8 3 1 0 3 3 3 0 LPP20 lipoprotein Dicer_dimer PF03368.14 KFM70247.1 - 0.042 14.0 0.3 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Dicer dimerisation domain FLYWCH PF04500.16 KFM70248.1 - 0.023 14.8 0.3 0.068 13.3 0.1 1.7 2 0 0 2 2 2 0 FLYWCH zinc finger domain C1_1 PF00130.22 KFM70249.1 - 1.4e-09 37.7 10.8 1.5e-09 37.5 10.8 1.0 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFM70249.1 - 0.015 15.6 7.3 0.023 15.0 7.3 1.3 1 0 0 1 1 1 0 C1 domain G-patch_2 PF12656.7 KFM70252.1 - 4.4e-24 84.3 0.2 4.4e-24 84.3 0.2 2.2 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 KFM70252.1 - 5.8e-09 35.7 0.7 1.1e-08 34.9 0.7 1.4 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 KFM70252.1 - 6e-06 26.0 0.2 8.1e-05 22.4 0.0 2.8 3 0 0 3 3 3 1 KOW motif KN17_SH3 PF18131.1 KFM70252.1 - 0.009 16.1 0.1 0.028 14.5 0.1 1.9 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain RR_TM4-6 PF06459.12 KFM70252.1 - 4.3 7.1 19.8 0.099 12.5 11.2 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KFM70252.1 - 5.3 5.2 17.4 0.26 9.5 12.1 1.5 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.22 KFM70252.1 - 7.7 5.6 8.7 14 4.8 8.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.25 KFM70253.1 - 6.4e-49 166.7 0.2 8.7e-49 166.3 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM70253.1 - 3.2e-22 79.0 0.1 9.7e-21 74.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase SDP_N PF12278.8 KFM70254.1 - 0.0056 16.8 0.3 0.0056 16.8 0.3 4.5 5 1 1 6 6 6 1 Sex determination protein N terminal Cytochrom_B559a PF00284.20 KFM70254.1 - 10 6.0 7.6 14 5.5 0.0 3.9 4 0 0 4 4 4 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit DDE_3 PF13358.6 KFM70257.1 - 1.5e-13 50.7 0.0 2.1e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease WGR PF05406.15 KFM70258.1 - 2.8e-19 69.0 0.3 5.1e-19 68.1 0.3 1.5 1 0 0 1 1 1 1 WGR domain PARP_reg PF02877.14 KFM70258.1 - 1.4e-18 67.3 0.1 4.7e-18 65.6 0.2 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain PARP PF00644.20 KFM70258.1 - 1e-15 57.8 0.2 2e-15 56.9 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain HTH_48 PF17906.1 KFM70259.1 - 0.0017 18.4 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase RT_RNaseH_2 PF17919.1 KFM70260.1 - 1.2e-30 105.5 0.0 2.9e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM70260.1 - 2.6e-27 95.2 0.0 1.2e-26 93.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM70260.1 - 1.5e-24 86.8 0.7 2.7e-24 85.9 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KFM70260.1 - 3.5e-18 65.5 0.0 9e-18 64.1 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM70260.1 - 7.1e-17 61.7 0.0 2.2e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFM70260.1 - 2.9e-06 27.4 0.4 6.3e-06 26.3 0.4 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DDE_Tnp_IS240 PF13610.6 KFM70260.1 - 0.028 14.7 0.2 0.14 12.4 0.2 2.2 1 0 0 1 1 1 0 DDE domain BH4 PF02180.17 KFM70260.1 - 0.038 13.8 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Bcl-2 homology region 4 Abhydrolase_1 PF00561.20 KFM70261.1 - 0.067 12.8 0.0 0.076 12.6 0.0 1.0 1 0 0 1 1 1 0 alpha/beta hydrolase fold HTH_24 PF13412.6 KFM70262.1 - 0.012 15.2 1.4 0.062 12.9 0.1 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Trp_repressor PF01371.19 KFM70262.1 - 0.015 15.4 1.8 0.046 13.9 0.7 2.1 1 1 1 2 2 2 0 Trp repressor protein HTH_38 PF13936.6 KFM70262.1 - 0.021 14.6 1.6 0.047 13.5 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_36 PF13730.6 KFM70262.1 - 0.03 14.3 3.2 0.39 10.7 0.2 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 KFM70262.1 - 0.034 14.2 1.0 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM70262.1 - 0.035 14.1 0.0 0.067 13.2 0.0 1.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KFM70262.1 - 0.05 13.4 0.6 0.91 9.4 0.1 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Mrr_cat_2 PF13156.6 KFM70262.1 - 0.08 12.8 0.9 0.12 12.3 0.9 1.3 1 0 0 1 1 1 0 Restriction endonuclease CENP-B_N PF04218.13 KFM70262.1 - 0.11 12.1 2.1 0.59 9.8 0.2 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_19 PF12844.7 KFM70262.1 - 0.15 12.1 0.9 13 5.9 0.9 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain Ndr PF03096.14 KFM70263.1 - 0.15 10.7 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 KFM70264.1 - 2.4e-20 73.3 0.0 2.7e-19 69.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM70264.1 - 1.5e-16 61.7 0.0 1.9e-16 61.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM70264.1 - 7.6e-08 31.9 0.0 1.4e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 KFM70264.1 - 3.7e-05 22.4 0.2 7.6e-05 21.4 0.1 1.8 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 KFM70264.1 - 0.00065 19.4 0.0 0.0018 18.0 0.0 1.7 2 1 0 2 2 2 1 Putative esterase PGAP1 PF07819.13 KFM70264.1 - 0.0035 17.1 0.0 0.024 14.4 0.1 2.0 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_2 PF02230.16 KFM70264.1 - 0.0041 16.9 0.0 4.7 7.0 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KFM70264.1 - 0.032 13.2 0.0 0.065 12.1 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF915 PF06028.11 KFM70264.1 - 0.041 13.2 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydro_lipase PF04083.16 KFM70264.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.7 KFM70264.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family DDE_3 PF13358.6 KFM70265.1 - 7.5e-16 58.2 0.1 6.2e-15 55.2 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70265.1 - 8e-16 58.1 6.5 1.5e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM70265.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70265.1 - 0.0022 17.8 0.2 0.12 12.2 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70265.1 - 0.016 15.4 0.1 0.068 13.3 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM70265.1 - 0.031 14.3 2.6 0.037 14.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix Abhydrolase_1 PF00561.20 KFM70266.1 - 9.8e-16 58.2 0.0 1.2e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM70266.1 - 2e-13 51.5 0.0 2.1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM70266.1 - 7.4e-08 31.9 0.0 8.3e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFM70266.1 - 1.8e-06 27.9 0.1 0.0018 18.1 0.2 2.1 1 1 1 2 2 2 2 PGAP1-like protein PAF-AH_p_II PF03403.13 KFM70266.1 - 0.0002 20.0 0.1 0.0081 14.7 0.0 2.1 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 KFM70266.1 - 0.0003 20.6 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.20 KFM70266.1 - 0.0022 17.7 0.0 0.0068 16.1 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 KFM70266.1 - 0.0076 16.0 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 KFM70266.1 - 0.015 14.9 0.0 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF915 PF06028.11 KFM70266.1 - 0.024 14.0 0.0 0.21 10.9 0.0 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 KFM70266.1 - 0.042 12.8 0.0 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme GvpH PF05455.11 KFM70266.1 - 0.14 12.2 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 GvpH Abhydrolase_1 PF00561.20 KFM70267.1 - 1.2e-11 44.8 0.1 1.3e-11 44.6 0.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM70267.1 - 2.4e-08 34.8 0.0 2.8e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM70267.1 - 1.1e-06 28.1 0.0 1.4e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFM70267.1 - 0.0074 16.0 0.6 0.24 11.1 0.0 2.0 1 1 1 2 2 2 1 PGAP1-like protein DUF915 PF06028.11 KFM70267.1 - 0.047 13.0 0.0 3.1 7.0 0.0 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.13 KFM70267.1 - 0.071 11.6 0.1 0.78 8.2 0.0 1.9 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydro_lipase PF04083.16 KFM70267.1 - 0.089 12.4 0.0 0.59 9.8 0.0 2.2 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_2 PF02230.16 KFM70267.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase HTH_Tnp_Tc3_2 PF01498.18 KFM70268.1 - 2.8e-15 56.3 1.3 1.1e-14 54.4 1.3 2.1 1 0 0 1 1 1 1 Transposase Integrase_H2C2 PF17921.1 KFM70268.1 - 3.3e-09 36.7 1.1 5.9e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KFM70268.1 - 0.00011 22.4 0.0 0.00043 20.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain HTH_28 PF13518.6 KFM70268.1 - 0.00037 20.6 6.1 1 9.5 0.1 3.6 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_3 PF01381.22 KFM70268.1 - 0.00044 20.2 1.2 0.054 13.6 0.0 3.1 2 0 0 2 2 2 1 Helix-turn-helix HTH_23 PF13384.6 KFM70268.1 - 0.0012 18.5 4.6 2.4 8.0 0.1 3.7 3 0 0 3 3 3 2 Homeodomain-like domain HTH_32 PF13565.6 KFM70268.1 - 0.0021 18.6 1.4 0.0021 18.6 1.4 4.3 4 1 1 5 5 5 1 Homeodomain-like domain MarR_2 PF12802.7 KFM70268.1 - 0.0029 17.5 0.7 0.21 11.5 0.0 3.1 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM70268.1 - 0.012 15.6 1.9 0.051 13.5 0.0 2.8 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM70268.1 - 0.077 12.6 1.9 1.3 8.6 0.0 3.3 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding FUR PF01475.19 KFM70268.1 - 0.094 12.9 0.1 1.6 8.9 0.1 2.5 2 0 0 2 2 2 0 Ferric uptake regulator family HTH_11 PF08279.12 KFM70268.1 - 0.5 10.4 2.7 14 5.7 0.2 3.7 4 0 0 4 4 4 0 HTH domain Abhydrolase_1 PF00561.20 KFM70269.1 - 2.4e-14 53.6 0.0 7.7e-14 52.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM70269.1 - 1.7e-10 41.9 0.0 3.5e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM70269.1 - 2.3e-07 30.4 0.0 4.9e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KFM70269.1 - 0.0063 16.2 0.0 0.019 14.6 0.0 1.8 1 1 1 2 2 2 1 Putative esterase Ndr PF03096.14 KFM70269.1 - 0.034 12.8 0.0 0.059 12.1 0.0 1.4 1 1 0 1 1 1 0 Ndr family PAF-AH_p_II PF03403.13 KFM70269.1 - 0.062 11.8 0.0 0.093 11.2 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II FBA_3 PF08268.12 KFM70269.1 - 0.079 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 F-box associated domain Abhydrolase_5 PF12695.7 KFM70269.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFM70269.1 - 0.12 12.2 0.0 2.2 8.0 0.0 2.6 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KFM70270.1 - 0.00033 20.4 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM70270.1 - 0.0011 18.4 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KFM70270.1 - 0.0016 18.2 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KFM70270.1 - 0.0034 17.2 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KFM70270.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KFM70270.1 - 0.026 15.1 0.0 0.027 15.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 KFM70270.1 - 0.044 13.1 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 KFM70270.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase ATP-grasp_2 PF08442.10 KFM70270.1 - 0.14 11.7 0.1 0.69 9.4 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain FhuF PF06276.12 KFM70270.1 - 0.15 12.5 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Abhydrolase_1 PF00561.20 KFM70271.1 - 7.8e-15 55.2 0.0 1.2e-14 54.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM70271.1 - 3.8e-11 44.0 0.0 4.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM70271.1 - 1e-05 25.0 0.0 1.2e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Pkinase_Tyr PF07714.17 KFM70272.1 - 9.8e-94 313.4 0.0 1.3e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM70272.1 - 1.8e-41 142.3 0.0 2.4e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFM70272.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Recep_L_domain PF01030.24 KFM70273.1 - 2.2e-54 182.3 0.2 2.7e-26 91.9 0.3 2.7 2 0 0 2 2 2 2 Receptor L domain Furin-like PF00757.20 KFM70273.1 - 2.6e-28 98.8 42.2 2.6e-28 98.8 42.2 1.8 2 0 0 2 2 2 1 Furin-like cysteine rich region fn3 PF00041.21 KFM70273.1 - 1.4e-19 70.2 5.4 2.4e-07 31.0 0.1 4.7 4 1 0 4 4 4 4 Fibronectin type III domain HTH_Tnp_Tc3_2 PF01498.18 KFM70275.1 - 7.7e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70275.1 - 4.8e-14 52.3 0.2 5.9e-13 48.8 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM70275.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70275.1 - 0.0025 17.6 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70275.1 - 0.014 15.5 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM70275.1 - 0.032 14.3 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM70276.1 - 2.4e-16 59.7 2.2 4.9e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70276.1 - 9.6e-14 51.4 0.0 1.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70277.1 - 2.2e-16 59.9 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70277.1 - 9.1e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70278.1 - 1.1e-15 57.6 2.7 6.6e-15 55.1 1.9 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70278.1 - 1.3e-11 44.4 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM70278.1 - 0.027 15.1 6.3 0.18 12.4 1.1 2.8 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM70278.1 - 0.18 11.8 0.8 0.98 9.4 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Rsm22 PF09243.10 KFM70279.1 - 4.9e-60 203.1 0.0 6.7e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_25 PF13649.6 KFM70279.1 - 0.012 16.3 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFM70279.1 - 0.046 14.5 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MmoB_DmpM PF02406.17 KFM70279.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 MmoB/DmpM family Peptidase_M74 PF03411.13 KFM70279.1 - 0.15 11.6 1.6 0.3 10.6 1.6 1.4 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase RVT_1 PF00078.27 KFM70281.1 - 1.9e-14 53.7 0.1 2.7e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_4 PF13637.6 KFM70282.1 - 2.3e-25 88.6 1.1 5.7e-15 55.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM70282.1 - 1.5e-18 66.6 1.7 9.8e-10 38.5 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM70282.1 - 1.5e-18 67.1 0.4 2.3e-18 66.5 0.4 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM70282.1 - 2.2e-16 59.5 0.5 1.5e-06 28.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFM70282.1 - 7e-15 53.7 0.4 3.1e-05 24.0 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat VWA_3_C PF18571.1 KFM70282.1 - 0.14 12.0 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM70283.1 - 4.3e-19 68.5 3.9 9.3e-19 67.5 2.1 2.4 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70283.1 - 1e-15 57.8 0.0 4.3e-15 55.7 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM70283.1 - 4.6e-07 29.8 0.8 0.00021 21.3 0.0 3.0 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM70283.1 - 5.8e-07 30.0 2.0 5.8e-07 30.0 2.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70283.1 - 2.3e-06 27.6 2.5 0.00012 22.2 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70283.1 - 3.9e-06 26.5 3.1 3.8e-05 23.3 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM70283.1 - 5.7e-06 26.3 0.5 6.2e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM70283.1 - 0.00022 21.1 0.5 0.0026 17.6 0.0 2.6 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM70283.1 - 0.0018 18.2 0.3 0.025 14.6 0.0 2.5 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 KFM70283.1 - 0.0027 17.7 0.0 3 8.0 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain GntR PF00392.21 KFM70283.1 - 0.037 13.7 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_22 PF13309.6 KFM70283.1 - 0.18 11.9 0.2 47 4.2 0.0 3.1 3 0 0 3 3 3 0 HTH domain HTH_30 PF13556.6 KFM70283.1 - 0.46 10.3 3.3 2.1 8.2 0.0 2.9 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain SH3_1 PF00018.28 KFM70284.1 - 2e-11 43.3 0.0 2.9e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM70284.1 - 1.8e-08 33.9 0.0 3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFM70284.1 - 4.3e-08 32.9 0.0 6.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain rve PF00665.26 KFM70285.1 - 7.4e-11 42.3 0.0 1.5e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KFM70285.1 - 0.00076 19.7 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 DDE domain P30 PF07390.11 KFM70285.1 - 0.0072 16.4 0.2 0.014 15.5 0.2 1.4 1 0 0 1 1 1 1 Mycoplasma P30 protein EBA-175_VI PF11556.8 KFM70285.1 - 0.0095 16.2 3.8 0.024 15.0 3.8 1.6 1 0 0 1 1 1 1 Erythrocyte binding antigen 175 Dehyd-heme_bind PF09098.10 KFM70285.1 - 0.049 13.3 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding YjeF_N PF03853.15 KFM70286.1 - 2.7e-35 121.8 0.0 3.2e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.25 KFM70286.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme AC_N PF16214.5 KFM70287.1 - 2.2e-18 66.6 0.1 2.3e-18 66.6 0.1 1.0 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region TMEM220 PF15071.6 KFM70287.1 - 0.043 14.6 0.0 0.043 14.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane family 220, helix DUF1053 PF06327.14 KFM70288.1 - 8.2e-08 32.8 0.2 1.2e-07 32.2 0.2 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) Guanylate_cyc PF00211.20 KFM70288.1 - 0.2 11.3 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain PRKCSH-like PF12999.7 KFM70292.1 - 1.9e-36 125.5 6.7 1.9e-36 125.5 6.7 2.6 2 1 1 3 3 3 1 Glucosidase II beta subunit-like EF-hand_5 PF13202.6 KFM70292.1 - 1.9e-07 30.2 0.8 0.026 14.0 0.3 3.1 2 1 1 3 3 3 2 EF hand EF-hand_1 PF00036.32 KFM70292.1 - 2.7e-07 29.6 1.4 0.002 17.6 0.0 3.0 1 1 1 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM70292.1 - 5.1e-06 26.0 1.4 0.011 15.6 0.0 2.9 1 1 1 2 2 2 2 EF-hand domain PRKCSH PF07915.13 KFM70292.1 - 0.0023 18.9 2.9 0.0028 18.6 0.1 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein EF-hand_8 PF13833.6 KFM70292.1 - 0.0069 16.2 2.0 1.4 8.8 0.5 3.1 1 1 1 2 2 2 2 EF-hand domain pair PRKCSH_1 PF13015.6 KFM70292.1 - 0.008 15.9 1.6 0.0092 15.7 0.1 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein EF-hand_7 PF13499.6 KFM70292.1 - 0.011 16.2 7.3 0.02 15.3 1.7 3.4 1 1 1 2 2 2 0 EF-hand domain pair Ldl_recept_a PF00057.18 KFM70292.1 - 0.012 15.9 16.6 0.15 12.3 4.3 2.8 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A DDE_Tnp_1_7 PF13843.6 KFM70293.1 - 3.2e-43 148.4 0.6 3.6e-43 148.2 0.6 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM70293.1 - 7.5e-06 25.7 0.0 9.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain IBR PF01485.21 KFM70294.1 - 3.3e-08 33.6 16.4 3.3e-08 33.6 16.4 2.5 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain V-ATPase_G_2 PF16999.5 KFM70294.1 - 0.1 13.0 0.3 0.45 11.0 0.2 2.0 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Ank_4 PF13637.6 KFM70295.1 - 6.1e-14 52.2 0.2 0.00023 21.7 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM70295.1 - 1.2e-13 51.5 2.0 1.1e-07 32.3 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFM70295.1 - 1.8e-13 50.3 1.2 0.00012 22.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat IBR PF01485.21 KFM70295.1 - 1.8e-12 47.3 2.6 1.8e-12 47.3 2.6 3.2 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain Ank_5 PF13857.6 KFM70295.1 - 8.5e-11 41.9 0.0 3.5e-05 24.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM70295.1 - 2.1e-08 33.8 0.8 0.11 13.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat zf-RING_2 PF13639.6 KFM70295.1 - 4.1e-05 23.8 16.6 0.00014 22.1 5.8 3.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM70295.1 - 0.00047 19.9 3.6 0.00047 19.9 3.6 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) CEBP_ZZ PF16366.5 KFM70295.1 - 0.0017 18.6 7.8 0.0036 17.5 0.4 2.8 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_UBOX PF13445.6 KFM70295.1 - 0.0076 16.3 19.2 0.016 15.2 2.6 3.5 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM70295.1 - 0.013 15.4 6.0 0.013 15.4 6.0 3.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM70295.1 - 0.018 15.0 4.8 0.018 15.0 4.8 3.9 4 0 0 4 4 4 0 zinc-RING finger domain Dus PF01207.17 KFM70296.1 - 2.8e-26 92.3 0.0 3.2e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KFM70296.1 - 0.028 13.9 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Beta_helix PF13229.6 KFM70297.1 - 0.0049 16.7 0.0 0.0056 16.5 0.0 1.1 1 0 0 1 1 1 1 Right handed beta helix region Beta_helix PF13229.6 KFM70298.1 - 2e-74 248.7 66.9 1.7e-27 96.2 16.1 4.7 1 1 4 5 5 5 4 Right handed beta helix region NosD PF05048.13 KFM70298.1 - 1.2e-31 109.8 26.7 7.9e-15 54.8 6.6 3.3 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) zf-UBR PF02207.20 KFM70298.1 - 6.9e-10 39.0 12.9 1.5e-09 37.9 12.9 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Phage_GPA PF05840.13 KFM70298.1 - 0.08 12.0 0.0 7.9 5.5 0.0 2.9 3 0 0 3 3 3 0 Bacteriophage replication gene A protein (GPA) FH2 PF02181.23 KFM70299.1 - 2e-80 270.7 5.5 2e-80 270.7 5.5 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Fer4_16 PF13484.6 KFM70299.1 - 1 10.3 2.6 15 6.6 2.6 3.3 1 0 0 1 1 1 0 4Fe-4S double cluster binding domain Neur_chan_LBD PF02931.23 KFM70300.1 - 0.079 12.4 0.0 0.099 12.1 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain HTH_28 PF13518.6 KFM70301.1 - 0.0002 21.4 0.0 0.00023 21.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM70301.1 - 0.0046 16.3 0.0 0.0054 16.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KFM70301.1 - 0.013 15.2 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Homeodomain-like domain Terminase_5 PF06056.12 KFM70301.1 - 0.04 13.8 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_38 PF13936.6 KFM70301.1 - 0.055 13.2 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 KFM70301.1 - 0.064 13.3 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_24 PF13412.6 KFM70301.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Neur_chan_LBD PF02931.23 KFM70302.1 - 3.4e-08 33.2 0.0 4.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2070 PF09843.9 KFM70302.1 - 0.0005 18.5 4.1 0.00061 18.2 4.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Neur_chan_memb PF02932.16 KFM70302.1 - 0.00058 20.0 3.7 0.00071 19.7 3.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF19 PF01579.18 KFM70303.1 - 0.003 17.4 5.8 0.013 15.3 5.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF19) Rhomboid PF01694.22 KFM70304.1 - 1.4e-23 83.6 5.1 2.3e-23 82.8 5.1 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KFM70304.1 - 0.0025 18.3 2.3 0.003 18.1 0.2 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) UIM PF02809.20 KFM70304.1 - 0.026 14.4 3.8 0.046 13.6 3.8 1.4 1 0 0 1 1 1 0 Ubiquitin interaction motif HTH_Tnp_Tc3_2 PF01498.18 KFM70306.1 - 6.7e-16 58.3 2.2 6.7e-16 58.3 2.2 2.4 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70306.1 - 1.2e-13 51.0 0.0 2.7e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70306.1 - 2.5e-12 46.4 5.7 8.1e-07 28.7 0.2 3.2 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.6 KFM70306.1 - 3.3e-12 45.8 2.5 7e-07 28.9 0.1 2.8 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 KFM70306.1 - 1.7e-09 37.7 2.1 4e-05 23.7 0.1 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KFM70306.1 - 8.2e-08 31.8 0.2 2.2e-05 24.0 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 KFM70306.1 - 1e-06 28.7 2.8 8.4e-05 22.5 0.1 2.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_50 PF18024.1 KFM70306.1 - 2.6e-05 23.7 0.4 0.0013 18.3 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM70306.1 - 0.00022 20.6 1.0 0.00092 18.6 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 KFM70306.1 - 0.00031 20.3 0.3 0.031 13.8 0.1 2.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_7 PF02796.15 KFM70306.1 - 0.0022 18.0 0.6 0.43 10.7 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase TnsD PF15978.5 KFM70306.1 - 0.0028 16.7 2.2 0.88 8.5 0.2 2.2 2 0 0 2 2 2 2 Tn7-like transposition protein D Sigma70_r4 PF04545.16 KFM70306.1 - 0.0062 16.0 1.5 0.01 15.3 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_1 PF00126.27 KFM70306.1 - 0.018 15.0 0.1 0.21 11.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family UPF0122 PF04297.14 KFM70306.1 - 0.02 15.1 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_Tnp_1 PF01527.20 KFM70306.1 - 0.051 13.9 1.6 0.48 10.8 0.0 2.6 2 0 0 2 2 2 0 Transposase HTH_Tnp_IS630 PF01710.16 KFM70306.1 - 0.063 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Transposase HTH_40 PF14493.6 KFM70306.1 - 0.078 13.4 0.3 3.2 8.3 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Mor PF08765.11 KFM70306.1 - 0.11 12.5 0.3 0.24 11.4 0.3 1.6 1 0 0 1 1 1 0 Mor transcription activator family HTH_32 PF13565.6 KFM70306.1 - 4.1 8.1 21.1 0.14 12.7 2.0 4.2 3 2 1 4 4 4 0 Homeodomain-like domain DSPc PF00782.20 KFM70307.1 - 1.4e-44 151.1 0.8 2e-44 150.6 0.1 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFM70307.1 - 5.3e-10 39.8 0.1 1.5e-08 35.1 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 KFM70307.1 - 4.6e-06 26.4 0.0 6.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KFM70307.1 - 0.0063 16.6 0.1 0.016 15.4 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate CDKN3 PF05706.12 KFM70307.1 - 0.0085 15.8 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 KFM70307.1 - 0.02 15.2 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Myotub-related PF06602.14 KFM70307.1 - 0.033 13.1 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain ERGIC_N PF13850.6 KFM70308.1 - 5.8e-17 61.8 0.3 6.6e-17 61.7 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF4817 PF16087.5 KFM70309.1 - 7e-13 48.2 0.5 1.2e-12 47.4 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) Retrotran_gag_2 PF14223.6 KFM70310.1 - 4.7e-27 94.3 3.6 7.9e-27 93.6 3.6 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KFM70310.1 - 3.4e-07 30.0 3.2 3.4e-07 30.0 3.2 2.3 1 1 0 2 2 2 1 GAG-pre-integrase domain rve PF00665.26 KFM70310.1 - 1.1e-06 28.9 0.0 0.0025 18.0 0.0 2.6 1 1 1 2 2 2 2 Integrase core domain zf-CCHC PF00098.23 KFM70310.1 - 0.00014 21.8 17.3 0.0067 16.5 2.9 3.0 3 0 0 3 3 3 2 Zinc knuckle YmgB PF10798.8 KFM70310.1 - 0.14 12.0 2.1 0.24 11.3 0.5 2.0 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR zf-CCHC_4 PF14392.6 KFM70310.1 - 0.25 11.1 9.9 3 7.6 0.5 3.6 3 0 0 3 3 3 0 Zinc knuckle DivIC PF04977.15 KFM70312.1 - 6.1 6.7 6.5 5.9 6.7 1.2 2.2 1 1 1 2 2 2 0 Septum formation initiator Lge1 PF11488.8 KFM70313.1 - 0.059 13.6 14.3 0.55 10.5 0.7 3.2 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 DUF2590 PF10761.9 KFM70313.1 - 0.086 13.0 0.7 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2590) FRB_dom PF08771.11 KFM70313.1 - 0.097 13.1 11.4 2.1 8.8 0.6 3.0 1 1 2 3 3 3 0 FKBP12-rapamycin binding domain Wbp11 PF09429.10 KFM70313.1 - 0.13 12.6 19.8 0.58 10.6 2.7 3.2 2 1 1 3 3 3 0 WW domain binding protein 11 HdeA PF06411.11 KFM70313.1 - 0.64 10.2 5.5 5.6 7.2 0.5 2.4 1 1 1 2 2 2 0 HdeA/HdeB family FapA PF03961.13 KFM70313.1 - 2.5 6.6 8.9 3.6 6.1 8.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A OrfB_IS605 PF01385.19 KFM70313.1 - 2.7 8.2 13.1 11 6.3 0.3 3.0 1 1 2 3 3 3 0 Probable transposase EST1_DNA_bind PF10373.9 KFM70313.1 - 2.8 7.4 7.3 25 4.2 7.3 1.9 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain LMBR1 PF04791.16 KFM70313.1 - 3 6.6 5.3 3.3 6.5 5.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-H PF05837.12 KFM70313.1 - 9.7 6.7 19.3 1 9.8 9.1 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Ras PF00071.22 KFM70314.1 - 1e-58 197.5 0.0 1.2e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM70314.1 - 3.8e-33 114.2 0.0 5.9e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM70314.1 - 8.2e-13 48.2 0.0 9.4e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM70314.1 - 4.2e-07 30.0 0.0 6.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM70314.1 - 2e-05 24.1 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFM70314.1 - 8.5e-05 22.5 0.1 0.003 17.5 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFM70314.1 - 0.00012 21.6 0.0 0.011 15.3 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KFM70314.1 - 0.0015 18.2 0.0 0.0049 16.5 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KFM70314.1 - 0.002 18.4 0.0 0.0066 16.7 0.0 1.9 1 1 1 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KFM70314.1 - 0.002 17.9 0.1 0.062 13.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 KFM70314.1 - 0.0027 17.0 0.3 0.015 14.6 0.1 2.0 2 1 0 2 2 2 1 Septin AAA_16 PF13191.6 KFM70314.1 - 0.0076 16.7 0.1 0.018 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KFM70314.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KFM70314.1 - 0.012 15.1 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KFM70314.1 - 0.015 15.0 0.1 0.11 12.2 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KFM70314.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFM70314.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFM70314.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 NTPase G-alpha PF00503.20 KFM70314.1 - 0.052 12.7 0.9 0.23 10.6 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit ATPase_2 PF01637.18 KFM70314.1 - 0.053 13.4 0.2 0.099 12.5 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 KFM70314.1 - 0.06 12.7 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KFM70314.1 - 0.089 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KFM70314.1 - 0.097 11.8 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KFM70314.1 - 0.13 12.7 0.0 0.39 11.1 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 KFM70314.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain RuvB_N PF05496.12 KFM70314.1 - 0.19 11.4 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DDE_Tnp_1_7 PF13843.6 KFM70315.1 - 0.00018 20.9 0.1 0.00019 20.8 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 AKAP7_NLS PF10469.9 KFM70316.1 - 0.00045 20.2 0.0 0.00045 20.2 0.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain AKAP7_NLS PF10469.9 KFM70317.1 - 5.3e-19 68.9 0.4 7.5e-19 68.4 0.4 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain CNP_C_terminal PF17839.1 KFM70317.1 - 0.04 14.7 0.1 0.1 13.4 0.1 1.6 1 0 0 1 1 1 0 C-terminal domain of cyclic nucleotide phosphodiesterase DDE_1 PF03184.19 KFM70318.1 - 1.9e-17 63.5 0.1 3.2e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM70318.1 - 5.5e-12 45.5 0.4 1.2e-11 44.5 0.4 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM70318.1 - 0.0039 16.9 0.0 0.013 15.3 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease CSD PF00313.22 KFM70319.1 - 7.4e-74 243.6 16.8 9e-14 51.1 0.0 10.1 10 0 0 10 10 10 7 'Cold-shock' DNA-binding domain S1-like PF14444.6 KFM70319.1 - 2.9e-13 49.5 2.5 0.13 12.2 0.1 6.9 7 0 0 7 7 7 3 S1-like SUZ-C PF12901.7 KFM70319.1 - 2e-07 30.9 0.2 5.4e-07 29.5 0.2 1.8 1 0 0 1 1 1 1 SUZ-C motif CusF_Ec PF11604.8 KFM70319.1 - 3.3e-06 27.0 3.9 34 4.5 0.0 8.1 9 0 0 9 9 9 0 Copper binding periplasmic protein CusF DUF11 PF01345.18 KFM70319.1 - 0.0016 18.7 0.0 12 6.2 0.0 4.7 6 0 0 6 6 6 1 Domain of unknown function DUF11 DUF2196 PF09962.9 KFM70319.1 - 0.0034 17.4 0.2 0.62 10.1 0.1 3.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2196) OB_RNB PF08206.11 KFM70319.1 - 7.3 6.4 11.5 8.2 6.2 0.5 4.4 4 0 0 4 4 4 0 Ribonuclease B OB domain Sushi PF00084.20 KFM70320.1 - 2.5e-62 207.3 45.2 2.2e-12 47.4 2.4 9.6 9 0 0 9 9 9 9 Sushi repeat (SCR repeat) HRM PF02793.22 KFM70320.1 - 2.8e-08 33.9 24.7 0.032 14.5 0.5 7.0 7 0 0 7 7 7 5 Hormone receptor domain DUF3589 PF12141.8 KFM70320.1 - 0.038 12.6 0.1 0.056 12.0 0.1 1.1 1 0 0 1 1 1 0 Beta-mannosyltransferases cEGF PF12662.7 KFM70320.1 - 0.058 13.3 13.3 15 5.6 0.2 5.5 4 0 0 4 4 4 0 Complement Clr-like EGF-like SAND PF01342.21 KFM70320.1 - 0.068 12.9 0.3 0.43 10.3 0.1 2.4 2 0 0 2 2 2 0 SAND domain NNMT_PNMT_TEMT PF01234.17 KFM70321.1 - 2.7e-33 115.3 0.0 3.1e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family p450 PF00067.22 KFM70322.1 - 9.4e-99 331.2 0.0 1.1e-98 331.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_holin_2_1 PF04971.12 KFM70322.1 - 0.13 12.3 0.1 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage P21 holin S LRR_6 PF13516.6 KFM70323.1 - 0.0002 21.1 2.6 0.0043 17.0 0.1 3.5 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.7 KFM70323.1 - 0.0034 17.8 25.8 0.67 10.5 0.7 6.4 4 3 3 7 7 7 4 Leucine Rich repeats (2 copies) Cbl_N2 PF02761.14 KFM70323.1 - 0.13 12.9 1.0 1.3 9.8 0.8 2.6 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain zf-H2C2_2 PF13465.6 KFM70324.1 - 8.5e-64 209.3 92.1 3.4e-08 33.6 0.5 11.1 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM70324.1 - 1.8e-48 160.3 101.6 2.7e-06 27.5 3.4 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70324.1 - 1.8e-33 112.3 93.4 0.0012 19.5 1.2 10.2 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM70324.1 - 1.1e-19 70.1 69.6 0.0054 17.1 0.8 10.4 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM70324.1 - 2.2e-17 62.8 62.4 0.029 14.7 0.8 11.2 9 2 1 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM70324.1 - 2.2e-15 56.2 67.5 0.0021 18.0 2.3 10.8 10 1 0 10 10 10 6 C2H2-type zinc finger zf-CHCC PF10276.9 KFM70324.1 - 6.3e-06 26.1 8.8 35 4.6 0.0 8.3 9 0 0 9 9 9 0 Zinc-finger domain zf-C2H2_9 PF16293.5 KFM70324.1 - 8.2e-06 25.6 41.0 1.2 9.1 0.3 9.0 3 3 7 10 10 10 4 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM70324.1 - 0.00025 20.8 24.2 0.052 13.4 0.2 7.2 3 3 5 8 8 8 2 GAGA factor ADK_lid PF05191.14 KFM70324.1 - 0.00063 19.7 37.0 0.18 11.8 1.2 6.3 5 1 1 6 6 6 3 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM70324.1 - 0.002 18.4 68.0 0.49 10.8 1.3 9.4 1 1 8 9 9 9 3 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM70324.1 - 0.0027 17.8 36.0 0.81 9.8 6.2 4.2 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM70324.1 - 0.0031 17.6 38.2 6.4 7.0 0.1 9.7 10 0 0 10 10 10 1 Uncharacterized protein conserved in bacteria (DUF2256) C1_1 PF00130.22 KFM70324.1 - 0.0068 16.3 54.6 1 9.3 3.8 9.1 3 3 5 8 8 8 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFM70324.1 - 0.06 14.1 34.8 1 10.2 1.7 5.4 1 1 6 7 7 7 0 zinc-ribbon family DUF2039 PF10217.9 KFM70324.1 - 0.11 12.9 37.1 0.66 10.4 5.2 5.1 1 1 3 5 5 5 0 Uncharacterized conserved protein (DUF2039) Zn-ribbon_8 PF09723.10 KFM70324.1 - 0.12 12.5 35.2 0.22 11.6 0.9 6.6 3 2 4 7 7 7 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.15 KFM70324.1 - 0.19 11.8 33.8 2 8.6 0.0 8.9 5 3 4 9 9 9 0 Sec23/Sec24 zinc finger zf-met2 PF12907.7 KFM70324.1 - 1.2 9.4 30.0 7.2 6.8 0.3 9.1 9 0 0 9 9 9 0 Zinc-binding XPA_N PF01286.18 KFM70324.1 - 2.6 8.1 36.5 6.1 7.0 0.1 9.6 10 0 0 10 10 10 0 XPA protein N-terminal zf-MYST PF17772.1 KFM70324.1 - 4.1 7.1 50.1 0.086 12.5 1.0 9.3 3 2 7 10 10 10 0 MYST family zinc finger domain zf-H2C2_5 PF13909.6 KFM70324.1 - 4.5 7.1 72.9 0.3 10.9 1.5 10.3 10 0 0 10 10 10 0 C2H2-type zinc-finger domain ig PF00047.25 KFM70325.1 - 0.00014 21.9 0.0 0.00015 21.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFM70325.1 - 0.0013 18.3 0.0 0.0013 18.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM70325.1 - 0.0016 18.5 0.0 0.0016 18.5 0.0 1.0 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain V-set PF07686.17 KFM70325.1 - 0.0048 17.1 0.0 0.0051 17.0 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFM70325.1 - 0.0082 16.2 0.0 0.0082 16.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM70325.1 - 0.013 16.0 0.0 0.016 15.8 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 KFM70325.1 - 0.03 14.6 0.0 0.03 14.6 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Chitin_bind_4 PF00379.23 KFM70326.1 - 3.5e-08 33.9 9.0 3.5e-08 33.9 9.0 1.9 2 0 0 2 2 2 1 Insect cuticle protein DUF1283 PF06932.11 KFM70327.1 - 0.064 13.5 0.3 0.064 13.5 0.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1283) Band_7 PF01145.25 KFM70331.1 - 1.8e-14 54.1 0.0 2e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFM70331.1 - 0.0054 16.5 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 SPFH domain-Band 7 family NitrOD5 PF11537.8 KFM70331.1 - 0.072 13.2 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 HTH_Tnp_Tc3_2 PF01498.18 KFM70332.1 - 2e-17 63.2 1.6 5.5e-16 58.6 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70332.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70334.1 - 4.9e-16 58.7 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70334.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70334.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70334.1 - 0.0027 17.5 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain DUF725 PF05267.12 KFM70336.1 - 0.047 13.7 0.6 0.087 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF725) NTP_transf_2 PF01909.23 KFM70336.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Peripla_BP_7 PF18610.1 KFM70336.1 - 0.12 12.5 0.3 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain Chitin_bind_4 PF00379.23 KFM70338.1 - 8.3e-11 42.3 1.4 3.8e-10 40.1 1.4 2.3 1 0 0 1 1 1 1 Insect cuticle protein DUF2790 PF10976.8 KFM70338.1 - 0.054 13.5 0.3 0.23 11.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2790) adh_short PF00106.25 KFM70343.1 - 1.6e-45 155.0 0.1 2e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM70343.1 - 2.1e-38 132.2 0.0 2.8e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM70343.1 - 7e-11 42.4 0.4 1.8e-10 41.0 0.5 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM70343.1 - 0.00027 20.5 0.1 0.00051 19.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM70343.1 - 0.00029 19.9 0.0 0.00039 19.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFM70343.1 - 0.007 15.5 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFM70343.1 - 0.14 11.3 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF5641 PF18701.1 KFM70344.1 - 2.1e-17 63.0 0.7 2.1e-17 63.0 0.7 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5641) Ca_bind_SSO6904 PF18249.1 KFM70344.1 - 0.01 16.1 6.8 2.4 8.6 1.0 3.4 3 0 0 3 3 3 0 Calcium binding protein SSO6904 3HCDH_N PF02737.18 KFM70344.1 - 0.65 9.9 3.6 1.3 8.9 3.6 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF5641 PF18701.1 KFM70345.1 - 5.9e-18 64.8 2.8 7.8e-18 64.4 2.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5641) adh_short PF00106.25 KFM70346.1 - 3.9e-47 160.3 0.0 4.9e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM70346.1 - 7.1e-43 146.8 0.0 8.6e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM70346.1 - 4e-12 46.4 0.1 1.9e-11 44.2 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM70346.1 - 1.1e-06 28.4 0.0 2.7e-06 27.0 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFM70346.1 - 1.2e-05 25.5 0.0 3e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KFM70346.1 - 0.0001 21.5 0.0 0.0002 20.6 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFM70346.1 - 0.00063 19.3 0.0 0.00089 18.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFM70346.1 - 0.009 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFM70346.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 KFM70346.1 - 0.016 15.1 0.0 0.039 13.8 0.0 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KFM70346.1 - 0.031 13.4 0.4 1.2 8.2 0.4 2.6 1 1 0 1 1 1 0 Male sterility protein DFP PF04127.15 KFM70346.1 - 0.11 12.3 0.0 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.17 KFM70346.1 - 0.15 12.7 0.1 0.33 11.6 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DDE_3 PF13358.6 KFM70347.1 - 2.1e-13 50.3 0.0 3.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Tnp_P_element PF12017.8 KFM70347.1 - 1.7e-11 44.0 0.6 5.4e-11 42.3 0.3 1.7 2 0 0 2 2 2 1 Transposase protein HTH_Tnp_Tc3_2 PF01498.18 KFM70347.1 - 2.4e-07 30.9 0.4 5.8e-06 26.5 0.7 2.4 2 0 0 2 2 2 1 Transposase adh_short PF00106.25 KFM70348.1 - 8.2e-48 162.5 0.1 9.7e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM70348.1 - 1.4e-43 149.1 0.0 1.8e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM70348.1 - 1.5e-09 38.1 1.3 6.8e-09 35.9 1.3 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM70348.1 - 0.00053 19.5 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFM70348.1 - 0.0032 16.6 0.1 0.005 16.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KFM70348.1 - 0.0034 17.6 0.1 0.0052 17.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain EphA2_TM PF14575.6 KFM70349.1 - 0.0046 17.8 0.0 0.0066 17.3 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 KFM70349.1 - 0.0046 17.6 0.0 0.0092 16.6 0.0 1.4 1 0 0 1 1 1 1 WW domain-binding protein 1 TMEM51 PF15345.6 KFM70349.1 - 0.017 15.0 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Vpu PF00558.19 KFM70349.1 - 0.018 14.8 0.2 0.026 14.3 0.2 1.2 1 0 0 1 1 1 0 Vpu protein DUF4051 PF13260.6 KFM70349.1 - 0.045 13.5 0.2 0.072 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DUF4307 PF14155.6 KFM70349.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) TMEM132D_C PF15706.5 KFM70349.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Orf78 PF06024.12 KFM70349.1 - 0.14 12.4 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) TMEM52 PF14979.6 KFM70349.1 - 0.18 11.7 2.4 15 5.5 0.0 2.9 1 1 1 2 2 2 0 Transmembrane 52 EB PF01683.18 KFM70350.1 - 4.5e-07 30.1 1.5 7.5e-07 29.3 1.5 1.3 1 0 0 1 1 1 1 EB module Ig_3 PF13927.6 KFM70350.1 - 3.4e-05 24.4 0.0 5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM70350.1 - 0.056 13.6 0.1 0.1 12.8 0.1 1.4 1 1 0 1 1 1 0 Immunoglobulin domain Nodulin_late PF07127.11 KFM70350.1 - 0.074 13.4 3.1 0.31 11.4 1.8 2.3 2 0 0 2 2 2 0 Late nodulin protein Ig_2 PF13895.6 KFM70350.1 - 0.078 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Ion_trans PF00520.31 KFM70351.1 - 4.5e-42 144.0 0.5 5e-42 143.8 0.5 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM70351.1 - 0.00014 20.7 4.3 0.056 12.1 0.4 2.2 1 1 1 2 2 2 2 Polycystin cation channel DUF2975 PF11188.8 KFM70351.1 - 0.028 14.3 3.0 0.094 12.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Ca_chan_IQ PF08763.11 KFM70352.1 - 1.1e-29 102.4 0.1 2.2e-29 101.5 0.1 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain Ion_trans PF00520.31 KFM70352.1 - 1.2e-21 77.1 0.0 1.2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM70352.1 - 0.0033 16.2 0.3 0.0051 15.5 0.3 1.3 1 0 0 1 1 1 1 Polycystin cation channel CAC1F_C PF16885.5 KFM70352.1 - 0.018 14.7 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Ank_2 PF12796.7 KFM70353.1 - 7.2e-45 151.5 10.0 2.6e-11 43.9 0.1 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM70353.1 - 1.9e-40 136.7 9.7 2.4e-11 43.9 0.5 7.4 6 1 2 8 8 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM70353.1 - 3.3e-37 126.1 10.4 1.2e-08 35.0 0.5 7.0 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KFM70353.1 - 8.2e-32 108.3 15.0 6.2e-06 26.4 0.0 8.7 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KFM70353.1 - 7.5e-30 99.7 13.1 0.0003 21.0 0.0 9.5 9 0 0 9 9 9 7 Ankyrin repeat Death PF00531.22 KFM70353.1 - 2.2e-12 47.0 0.3 1.4e-11 44.4 0.0 2.6 3 0 0 3 3 3 1 Death domain COR PF16095.5 KFM70353.1 - 1.4e-05 25.0 1.0 2.8e-05 24.0 1.0 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 KFM70353.1 - 0.00038 20.7 0.1 1.1 9.5 0.1 2.7 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFM70353.1 - 0.0015 18.5 0.1 0.04 13.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase Ras PF00071.22 KFM70353.1 - 0.01 15.4 0.0 5.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Ras family DUF3737 PF12541.8 KFM70353.1 - 0.087 12.0 0.6 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3737) AAA_16 PF13191.6 KFM70353.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain MutS_III PF05192.18 KFM70353.1 - 0.12 12.6 0.1 47 4.1 0.0 3.3 3 0 0 3 3 3 0 MutS domain III AAA_23 PF13476.6 KFM70353.1 - 0.15 12.5 0.3 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fe-ADH PF00465.19 KFM70354.1 - 7.2e-111 370.5 0.0 8.2e-111 370.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KFM70354.1 - 1.6e-15 57.5 0.0 8.3e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF2321 PF10083.9 KFM70355.1 - 0.27 10.9 8.4 0.038 13.6 3.7 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Ogr_Delta PF04606.12 KFM70355.1 - 0.51 10.4 0.1 0.51 10.4 0.1 3.5 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger RecR PF02132.15 KFM70355.1 - 0.79 9.3 6.7 11 5.7 4.3 2.5 2 0 0 2 2 2 0 RecR protein RFC1 PF08519.12 KFM70356.1 - 5e-57 192.5 0.0 1.3e-56 191.2 0.0 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 KFM70356.1 - 5.3e-17 62.5 0.0 1.7e-16 60.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 KFM70356.1 - 4.1e-15 55.9 0.0 2.1e-14 53.6 0.0 2.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 KFM70356.1 - 1.4e-06 28.3 2.2 8.9e-06 25.7 0.1 3.2 2 1 0 2 2 2 1 Rad17 P-loop domain PTCB-BRCT PF12738.7 KFM70356.1 - 0.0001 22.2 0.1 0.00026 20.9 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain AAA_16 PF13191.6 KFM70356.1 - 0.00018 21.9 0.0 0.00056 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM70356.1 - 0.0002 21.6 0.0 0.00063 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFM70356.1 - 0.00037 20.5 0.0 0.0014 18.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM70356.1 - 0.00083 19.4 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) BRCT_2 PF16589.5 KFM70356.1 - 0.0011 19.3 0.0 0.0039 17.6 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain AAA_18 PF13238.6 KFM70356.1 - 0.0013 19.3 0.0 0.009 16.6 0.0 2.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM70356.1 - 0.0016 18.2 0.0 0.0044 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFM70356.1 - 0.0026 18.1 0.0 0.014 15.7 0.0 2.3 1 1 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 KFM70356.1 - 0.0031 17.3 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFM70356.1 - 0.0075 16.4 0.0 0.022 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KFM70356.1 - 0.028 14.7 1.2 15 6.0 0.0 4.0 4 0 0 4 4 3 0 AAA C-terminal domain NTPase_1 PF03266.15 KFM70356.1 - 0.045 13.7 0.9 0.47 10.3 0.1 2.6 1 1 1 2 2 2 0 NTPase NACHT PF05729.12 KFM70356.1 - 0.075 13.0 0.0 0.33 10.9 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 KFM70356.1 - 0.078 13.4 4.5 0.08 13.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain PAS_9 PF13426.7 KFM70358.1 - 5e-05 23.5 0.0 0.00029 21.0 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFM70358.1 - 0.06 13.3 0.0 0.85 9.6 0.0 2.3 3 0 0 3 3 3 0 PAS fold PAS_8 PF13188.7 KFM70358.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.5 1 1 0 1 1 1 0 PAS domain Pkinase PF00069.25 KFM70359.1 - 5.1e-54 183.4 0.0 7.8e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM70359.1 - 6.5e-24 84.6 0.0 8.9e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM70359.1 - 3.7e-05 22.7 0.1 8.2e-05 21.5 0.1 1.7 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM70359.1 - 0.00012 21.1 0.9 0.00023 20.2 0.9 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM70359.1 - 0.00051 19.4 0.0 0.00079 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM70359.1 - 0.0037 16.7 0.1 0.0061 15.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFM70359.1 - 0.0039 16.8 0.1 0.0077 15.9 0.1 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFM70359.1 - 0.011 15.6 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KFM70361.1 - 4.1e-33 114.9 0.0 6.2e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM70361.1 - 8.6e-20 71.1 0.0 1.2e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM70361.1 - 0.0025 16.7 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM70361.1 - 0.013 15.5 0.0 1.3 8.9 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Acyl_transf_3 PF01757.22 KFM70362.1 - 0.086 11.9 2.0 0.094 11.8 0.8 1.7 2 0 0 2 2 2 0 Acyltransferase family CBM_14 PF01607.24 KFM70365.1 - 1.6e-246 796.7 385.5 1.4e-12 47.5 4.5 26.5 26 0 0 26 26 26 26 Chitin binding Peritrophin-A domain DUF5401 PF17380.2 KFM70365.1 - 0.009 14.1 32.1 0.031 12.4 1.1 7.5 2 2 6 8 8 8 4 Family of unknown function (DUF5401) OATP PF03137.20 KFM70366.1 - 0.076 11.3 8.1 0.055 11.7 6.3 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CbtA PF09490.10 KFM70366.1 - 0.2 11.4 8.9 0.089 12.6 4.4 2.1 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) MFS_1 PF07690.16 KFM70368.1 - 1.3e-34 119.7 43.9 1.7e-32 112.8 32.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Cytochrome-c551 PF10643.9 KFM70368.1 - 0.03 13.9 0.9 0.082 12.5 0.9 1.7 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF373 PF04123.13 KFM70368.1 - 3.7 6.9 9.3 0.34 10.3 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) HTH_Tnp_Tc3_2 PF01498.18 KFM70369.1 - 2.8e-16 59.5 2.2 5.1e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70369.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70370.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70370.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70370.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70370.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70370.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Retrotran_gag_2 PF14223.6 KFM70371.1 - 3.3e-40 136.9 2.6 5.5e-40 136.2 2.6 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KFM70371.1 - 0.0031 17.2 5.7 0.0095 15.6 5.7 1.8 1 0 0 1 1 1 1 C2H2 zinc-finger TraY PF05509.11 KFM70371.1 - 0.029 14.4 0.3 0.069 13.2 0.3 1.7 1 0 0 1 1 1 0 TraY domain zf-CCHC_4 PF14392.6 KFM70371.1 - 0.1 12.4 1.7 0.22 11.3 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle HTH_Tnp_Tc3_2 PF01498.18 KFM70372.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70372.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease C2-set_2 PF08205.12 KFM70374.1 - 6.9e-05 22.8 0.0 9.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFM70374.1 - 0.0002 21.6 0.0 0.00035 20.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM70374.1 - 0.00049 20.6 0.0 0.00085 19.9 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM70374.1 - 0.17 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain DUF21 PF01595.20 KFM70376.1 - 2.2e-29 102.4 0.1 3e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KFM70376.1 - 2.2e-09 37.6 0.2 0.0027 18.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain KorB PF08535.10 KFM70376.1 - 0.049 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 KorB domain DegS PF05384.11 KFM70376.1 - 0.21 11.1 2.7 0.29 10.6 0.9 2.0 2 0 0 2 2 2 0 Sensor protein DegS cNMP_binding PF00027.29 KFM70377.1 - 0.00065 19.7 0.0 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Endonuc-PvuII PF09225.10 KFM70377.1 - 0.023 14.4 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease PvuII rve PF00665.26 KFM70378.1 - 0.019 15.1 0.0 0.58 10.4 0.0 2.3 2 1 0 2 2 2 0 Integrase core domain BTB_2 PF02214.22 KFM70379.1 - 3.7e-12 46.4 0.0 8.2e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 KFM70379.1 - 0.52 11.3 5.1 1e+02 4.0 0.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat HTH_Tnp_Tc3_2 PF01498.18 KFM70381.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70381.1 - 7.3e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70382.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70382.1 - 8.4e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease IF4E PF01652.18 KFM70383.1 - 5.5e-45 153.0 0.8 6.9e-45 152.7 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Aminotran_1_2 PF00155.21 KFM70384.1 - 0.00029 20.1 0.0 0.00035 19.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3692 PF12469.8 KFM70384.1 - 0.066 13.4 0.0 0.25 11.6 0.0 1.7 1 1 0 2 2 2 0 CRISPR-associated protein VioE PF18234.1 KFM70384.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE Hyccin PF09790.9 KFM70385.1 - 3.4e-58 197.3 0.1 4.3e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 Hyccin Hyccin PF09790.9 KFM70386.1 - 1.3e-15 57.4 0.1 1.4e-15 57.2 0.1 1.0 1 0 0 1 1 1 1 Hyccin 3HCDH_N PF02737.18 KFM70387.1 - 2.9e-39 134.8 0.0 3.7e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFM70387.1 - 1.9e-11 44.4 0.0 4.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain KIX PF02172.16 KFM70387.1 - 0.075 13.3 0.0 11 6.4 0.0 2.4 2 0 0 2 2 2 0 KIX domain TFA2_Winged_2 PF18121.1 KFM70387.1 - 0.1 12.3 0.1 14 5.5 0.0 2.8 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 HTH_Tnp_Tc3_2 PF01498.18 KFM70388.1 - 4.7e-16 58.8 3.5 5.6e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70388.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70388.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70388.1 - 0.0026 17.5 0.6 0.0074 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70388.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM70389.1 - 2.7e-16 59.6 2.2 4.9e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70389.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM70390.1 - 0.08 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70391.1 - 2.5e-16 59.7 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70391.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Phospholip_A2_2 PF05826.12 KFM70393.1 - 0.016 15.5 2.9 0.023 14.9 2.9 1.3 1 0 0 1 1 1 0 Phospholipase A2 CD20 PF04103.15 KFM70393.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 CD20-like family TMEM51 PF15345.6 KFM70393.1 - 0.083 12.7 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DDE_1 PF03184.19 KFM70394.1 - 0.00019 21.1 0.2 0.00022 20.9 0.2 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease THAP PF05485.12 KFM70396.1 - 7.3e-08 33.2 1.4 1.2e-07 32.6 1.4 1.3 1 1 0 1 1 1 1 THAP domain Gly_acyl_tr_C PF08444.10 KFM70397.1 - 0.017 15.3 0.1 0.029 14.6 0.1 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region XendoU PF09412.10 KFM70398.1 - 0.036 13.3 0.0 0.04 13.1 0.0 1.0 1 0 0 1 1 1 0 Endoribonuclease XendoU DUF1759 PF03564.15 KFM70399.1 - 1.2e-15 57.8 0.0 1.7e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) HTH_Tnp_Tc5 PF03221.16 KFM70400.1 - 7.1e-15 54.8 0.0 8.1e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain GCV_H PF01597.19 KFM70400.1 - 0.024 14.5 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage H-protein HTH_32 PF13565.6 KFM70401.1 - 0.0031 18.1 0.0 0.0081 16.8 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_48 PF17906.1 KFM70401.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Tnp_zf-ribbon_2 PF13842.6 KFM70404.1 - 0.013 16.3 9.8 0.019 15.8 9.8 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF2118 PF09891.9 KFM70404.1 - 0.074 13.0 0.0 0.076 13.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DDE_Tnp_1_7 PF13843.6 KFM70405.1 - 5.2e-26 91.8 2.1 6.2e-26 91.5 2.1 1.1 1 0 0 1 1 1 1 Transposase IS4 ubiquitin PF00240.23 KFM70406.1 - 6.8e-07 29.0 0.2 2e-06 27.4 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KFM70406.1 - 4.6e-06 27.0 0.1 3.2e-05 24.3 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 KFM70406.1 - 0.023 14.5 0.2 0.09 12.6 0.2 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_3 PF14836.6 KFM70406.1 - 0.052 13.5 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain PI3K_rbd PF00794.18 KFM70406.1 - 0.08 13.1 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain ECSIT PF06239.11 KFM70408.1 - 1.2e-73 247.0 1.9 1.9e-73 246.3 1.9 1.2 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway ECSIT_C PF14784.6 KFM70408.1 - 7.9e-41 139.5 0.0 1.5e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of the ECSIT protein Pox_G9-A16 PF03003.16 KFM70408.1 - 0.035 13.8 0.5 0.066 12.9 0.5 1.4 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 Imm2 PF14426.6 KFM70408.1 - 0.045 13.8 0.0 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm2 Sushi PF00084.20 KFM70409.1 - 4.6e-05 23.9 11.7 0.00055 20.5 1.7 2.5 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Phospholip_A2_1 PF00068.19 KFM70410.1 - 1e-19 71.0 1.3 1.3e-19 70.8 1.3 1.1 1 0 0 1 1 1 1 Phospholipase A2 PNRC PF15365.6 KFM70412.1 - 0.00043 20.0 0.4 0.00043 20.0 0.4 2.2 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif DAZAP2 PF11029.8 KFM70412.1 - 0.016 16.2 1.2 0.019 15.9 1.2 1.1 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) SWIM PF04434.17 KFM70413.1 - 0.00025 20.6 2.5 0.00048 19.7 2.5 1.5 1 0 0 1 1 1 1 SWIM zinc finger 2-Hacid_dh_C PF02826.19 KFM70414.1 - 5.3e-05 22.6 0.2 6.7e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIIE_beta PF02186.15 KFM70416.1 - 3.7e-21 75.2 0.3 1.2e-20 73.6 0.1 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 KFM70416.1 - 1.9e-08 33.8 0.5 6e-08 32.3 0.1 2.0 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 Coprogen_oxidas PF01218.18 KFM70416.1 - 0.016 14.0 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase ANF_receptor PF01094.28 KFM70416.1 - 0.041 13.0 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region PhoQ_Sensor PF08918.10 KFM70416.1 - 0.074 12.9 0.9 0.12 12.2 0.9 1.3 1 0 0 1 1 1 0 PhoQ Sensor UNC-79 PF14776.6 KFM70418.1 - 2.5e-219 729.4 16.9 2.1e-143 478.9 5.8 2.0 1 1 1 2 2 2 2 Cation-channel complex subunit UNC-79 Swi6_N PF18530.1 KFM70418.1 - 0.0065 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Swi6 N-terminal domain zinc_ribbon_15 PF17032.5 KFM70418.1 - 0.67 10.7 7.5 0.6 10.9 1.1 2.5 2 0 0 2 2 2 0 zinc-ribbon family HEAT PF02985.22 KFM70420.1 - 0.056 13.7 0.0 6.9 7.2 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat Cobalamin_bind PF01122.19 KFM70424.1 - 1.4e-19 70.2 0.3 2.6e-19 69.3 0.3 1.3 1 1 0 1 1 1 1 Eukaryotic cobalamin-binding protein Ldl_recept_a PF00057.18 KFM70424.1 - 5.7e-17 61.6 30.6 1.9e-09 37.6 8.4 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A TED_complement PF07678.14 KFM70424.1 - 0.00077 18.6 0.1 0.01 14.9 0.1 2.2 2 0 0 2 2 2 1 A-macroglobulin TED domain SQHop_cyclase_C PF13243.6 KFM70424.1 - 0.017 14.2 0.4 0.06 12.4 0.1 1.9 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain DUF3439 PF11921.8 KFM70424.1 - 0.72 9.8 5.9 1.9 8.5 5.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Exo_endo_phos PF03372.23 KFM70425.1 - 8.1e-06 25.5 0.0 8.6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF789 PF05623.12 KFM70425.1 - 0.19 11.4 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Phosphonate-bd PF12974.7 KFM70426.1 - 1.2e-32 113.5 0.0 1.5e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein zf-C2H2 PF00096.26 KFM70428.1 - 1.4e-09 37.8 45.1 0.0001 22.5 1.4 7.1 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70428.1 - 4.1e-08 33.4 47.8 0.0011 19.6 0.8 7.2 7 1 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 KFM70428.1 - 0.0002 21.6 32.7 0.0033 17.8 0.8 6.2 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM70428.1 - 0.00033 20.9 31.2 0.00035 20.8 1.2 6.1 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM70428.1 - 0.0027 17.7 30.9 0.038 14.0 1.2 5.8 5 1 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM70428.1 - 0.0048 17.2 28.3 1.3 9.5 0.7 5.5 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFM70428.1 - 0.12 12.7 1.6 18 5.7 0.1 3.1 1 1 2 3 3 3 0 BolA-like protein DUF4187 PF13821.6 KFM70428.1 - 0.24 11.2 5.1 4.1 7.3 0.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf-BED PF02892.15 KFM70428.1 - 0.36 10.9 27.2 4.7 7.3 1.4 5.8 4 2 1 5 5 5 0 BED zinc finger zf-H2C2_2 PF13465.6 KFM70428.1 - 1.2 9.7 0.1 1.2 9.7 0.1 7.1 7 1 0 7 7 7 0 Zinc-finger double domain DDE_1 PF03184.19 KFM70429.1 - 2.3e-16 60.0 0.0 2.9e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 KFM70430.1 - 3.8e-65 219.9 0.0 6.1e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM70430.1 - 8.8e-48 162.8 0.0 1.7e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KFM70430.1 - 2.9e-15 56.3 2.4 1.8e-14 53.7 2.4 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) MIT PF04212.18 KFM70430.1 - 0.00046 20.2 2.1 0.0023 17.9 0.4 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Kdo PF06293.14 KFM70430.1 - 0.0015 18.0 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM70430.1 - 0.038 13.3 0.0 0.16 11.2 0.0 2.0 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KFM70430.1 - 0.041 12.7 0.0 0.09 11.5 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase 2OG-FeII_Oxy_2 PF13532.6 KFM70431.1 - 1.3e-17 64.7 0.0 3.3e-17 63.3 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 KFM70431.1 - 3e-16 59.8 0.1 7.2e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM70431.1 - 1.5e-13 51.2 0.1 3.6e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 KFM70431.1 - 2.7e-10 39.9 0.0 5.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.6 KFM70431.1 - 1.5e-07 31.4 0.1 3e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM70431.1 - 1.6e-06 28.1 0.0 2.7e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFM70431.1 - 5.5e-06 26.4 0.3 1.1e-05 25.4 0.3 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.12 KFM70431.1 - 1.8e-05 25.4 0.1 5.9e-05 23.7 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM70431.1 - 3.7e-05 23.2 0.0 0.00053 19.4 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family RRM_occluded PF16842.5 KFM70431.1 - 0.00087 19.1 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif MetW PF07021.12 KFM70431.1 - 0.0012 18.4 0.1 0.0023 17.6 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW ARS2 PF04959.13 KFM70431.1 - 0.021 15.2 0.1 0.046 14.1 0.1 1.5 1 0 0 1 1 1 0 Arsenite-resistance protein 2 NodS PF05401.11 KFM70431.1 - 0.084 12.5 0.3 0.23 11.0 0.3 1.7 1 1 0 1 1 1 0 Nodulation protein S (NodS) DEAD PF00270.29 KFM70435.1 - 6.7e-53 179.1 0.0 3.2e-52 176.8 0.0 2.0 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM70435.1 - 1.4e-32 112.4 0.2 2.4e-31 108.4 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM70435.1 - 2.4e-06 27.7 0.0 1e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFM70435.1 - 0.00023 20.5 0.1 0.00035 19.9 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 KFM70435.1 - 0.0013 18.5 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFM70435.1 - 0.0056 17.0 0.0 0.94 9.8 0.0 2.6 1 1 1 2 2 2 2 AAA domain Helicase_C_2 PF13307.6 KFM70435.1 - 0.056 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain SecA_DEAD PF07517.14 KFM70435.1 - 0.067 12.5 0.1 11 5.2 0.0 2.7 3 0 0 3 3 3 0 SecA DEAD-like domain DUF5335 PF17269.2 KFM70435.1 - 0.1 12.4 0.8 0.28 11.1 0.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Helicase_RecD PF05127.14 KFM70435.1 - 0.13 12.1 0.0 3.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Helicase DUF1871 PF08958.10 KFM70435.1 - 0.22 11.9 1.0 2.2 8.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1871) zf-C2H2_4 PF13894.6 KFM70436.1 - 1e-20 72.6 45.6 0.0069 17.1 1.4 7.4 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM70436.1 - 6.9e-19 67.2 50.1 0.00035 20.9 2.7 7.5 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM70436.1 - 6.3e-17 61.2 58.7 6.4e-05 23.2 0.5 8.2 8 1 0 8 8 8 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM70436.1 - 9.4e-07 29.0 38.0 0.041 14.2 0.0 7.4 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFM70436.1 - 0.00053 20.2 22.5 0.001 19.3 2.2 4.0 1 1 3 4 4 4 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFM70436.1 - 0.0017 18.6 30.6 0.56 10.6 0.5 6.7 1 1 6 7 7 7 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFM70436.1 - 0.0025 18.2 24.2 1.4 9.4 0.6 6.0 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM70436.1 - 0.34 11.0 44.4 0.094 12.7 0.9 7.2 7 1 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM70436.1 - 0.99 9.3 9.6 0.92 9.4 0.1 4.3 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) PyrI_C PF02748.15 KFM70436.1 - 1.1 9.2 18.9 0.5 10.3 0.6 4.6 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KFM70436.1 - 2.7 8.8 19.7 12 6.8 1.4 3.6 1 1 3 4 4 4 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM70436.1 - 7.6 6.8 22.4 3.4 7.9 2.4 4.6 4 1 0 4 4 4 0 Zinc ribbon domain zf-C2HE PF16278.5 KFM70436.1 - 8.6 6.9 42.0 0.16 12.5 0.7 5.4 4 3 1 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C4pol PF14260.6 KFM70436.1 - 9.6 6.8 18.4 0.72 10.4 0.6 3.8 3 2 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Got1 PF04178.12 KFM70437.1 - 1.1e-26 93.5 10.9 1.6e-26 93.0 10.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family VGCC_beta4Aa_N PF12052.8 KFM70437.1 - 0.07 13.3 2.6 0.18 11.9 2.6 1.7 1 1 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Claudin_2 PF13903.6 KFM70437.1 - 0.21 11.3 5.3 0.039 13.7 0.9 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction HTH_Tnp_Tc3_2 PF01498.18 KFM70438.1 - 1.9e-16 60.1 2.2 4.2e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70438.1 - 1.3e-13 50.9 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Chorein_N PF12624.7 KFM70439.1 - 1.1e-34 119.0 0.0 1.2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 PAS_11 PF14598.6 KFM70440.1 - 1e-36 125.5 0.6 2.4e-33 114.6 0.4 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KFM70440.1 - 2.8e-10 40.2 0.1 0.00027 20.9 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.12 KFM70440.1 - 1.8e-09 37.7 0.0 4.4e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFM70440.1 - 0.00022 21.5 0.1 0.009 16.3 0.1 2.8 2 1 0 2 2 2 1 PAS domain SATase_N PF06426.14 KFM70440.1 - 0.072 13.5 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Gal4_dimer PF03902.13 KFM70440.1 - 0.84 9.9 3.0 2.9 8.1 0.8 2.8 2 0 0 2 2 2 0 Gal4-like dimerisation domain HTH_Tnp_Tc3_2 PF01498.18 KFM70441.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70441.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM70442.1 - 3.8e-16 59.2 0.1 4.6e-15 55.6 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70442.1 - 6.8e-16 58.3 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM70442.1 - 0.00068 20.2 1.5 0.00068 20.2 1.5 2.7 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70442.1 - 0.0022 17.7 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70442.1 - 0.014 15.5 0.1 0.061 13.5 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM70442.1 - 0.031 14.3 2.6 0.033 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM70443.1 - 2.3e-10 40.4 0.0 2.6e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease MAM PF00629.23 KFM70444.1 - 2.7e-263 862.8 22.3 1.2e-32 113.0 0.0 10.8 10 1 0 10 10 10 10 MAM domain, meprin/A5/mu FBA_3 PF08268.12 KFM70444.1 - 0.058 13.3 0.2 10 6.1 0.0 2.9 3 0 0 3 3 3 0 F-box associated domain Ldl_recept_a PF00057.18 KFM70444.1 - 2.3 8.5 8.8 8.3 6.7 8.8 2.0 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A MAM PF00629.23 KFM70445.1 - 0 2234.4 90.7 7.5e-37 126.7 0.0 26.3 26 0 0 26 26 26 26 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 KFM70445.1 - 1.5e-90 297.1 244.2 3.5e-09 36.7 8.2 14.9 14 0 0 14 14 14 14 Low-density lipoprotein receptor domain class A Hen1_Lam_C PF18441.1 KFM70445.1 - 0.012 15.4 0.8 0.35 10.7 0.2 3.2 3 0 0 3 3 3 0 Hen1 La-motif C-terminal domain zf-C2H2 PF00096.26 KFM70446.1 - 4.1e-10 39.5 16.6 1.3e-05 25.4 0.7 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70446.1 - 1.5e-08 34.8 23.5 0.0029 18.3 0.7 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger CENP-P PF13096.6 KFM70446.1 - 0.00032 20.4 0.1 0.00075 19.2 0.1 1.6 1 0 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P zf-H2C2_2 PF13465.6 KFM70446.1 - 0.00035 20.9 13.6 0.0055 17.1 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM70446.1 - 0.0038 17.5 5.1 0.026 14.8 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM70446.1 - 0.036 14.3 8.4 0.065 13.5 4.1 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFM70446.1 - 0.14 11.9 0.2 0.14 11.9 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf_UBZ PF18439.1 KFM70446.1 - 0.22 11.1 5.2 1.4 8.6 0.2 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 KFM70446.1 - 0.25 11.0 0.2 0.25 11.0 0.2 4.3 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain AMP-binding PF00501.28 KFM70447.1 - 1.3e-54 185.5 0.0 1.6e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UBM PF14377.6 KFM70448.1 - 7.9e-29 98.2 12.4 3e-12 45.5 1.8 3.9 3 0 0 3 3 3 3 Ubiquitin binding region Phage_Arf PF17585.2 KFM70448.1 - 0.48 10.4 5.1 0.86 9.6 1.3 2.6 2 0 0 2 2 2 0 Accessory recombination function protein SDA1 PF05285.12 KFM70449.1 - 0.15 11.4 11.5 0.3 10.5 11.5 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KFM70449.1 - 1.2 7.3 13.9 1.7 6.7 13.9 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 KFM70449.1 - 1.5 7.5 4.7 2.4 6.8 4.7 1.3 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 KFM70449.1 - 1.7 8.1 17.4 1.9 8.0 13.0 2.6 3 0 0 3 3 3 0 PPP4R2 DUF913 PF06025.12 KFM70450.1 - 1.9e-90 303.5 0.9 5.2e-90 302.1 0.0 2.3 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) WWE PF02825.20 KFM70450.1 - 4.1e-13 49.7 1.6 1e-12 48.5 1.6 1.7 1 0 0 1 1 1 1 WWE domain UBA PF00627.31 KFM70450.1 - 2.3e-06 27.4 0.2 3.3e-05 23.7 0.0 2.8 3 0 0 3 3 3 1 UBA/TS-N domain UIM PF02809.20 KFM70450.1 - 0.0045 16.8 0.6 0.012 15.4 0.6 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Pinin_SDK_N PF04697.13 KFM70450.1 - 0.11 13.2 0.3 0.34 11.6 0.3 1.8 1 0 0 1 1 1 0 pinin/SDK conserved region DUF5638 PF18688.1 KFM70451.1 - 0.12 12.6 0.5 0.25 11.7 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5638) 14-3-3 PF00244.20 KFM70452.1 - 2.9e-107 357.2 4.3 3.4e-107 357.0 4.3 1.1 1 0 0 1 1 1 1 14-3-3 protein HTH_Tnp_Tc3_2 PF01498.18 KFM70453.1 - 5.2e-16 58.7 3.7 5.6e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70453.1 - 2.9e-13 49.8 0.0 5.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70453.1 - 3.2e-07 30.0 1.3 1e-06 28.4 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70453.1 - 0.012 15.4 0.7 0.033 14.0 0.7 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM70453.1 - 2.9 8.6 16.1 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM70454.1 - 3.9e-16 59.0 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70454.1 - 1.5e-13 50.7 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70454.1 - 3.3e-07 30.0 1.6 7.7e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70454.1 - 0.003 17.3 0.6 0.0083 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70454.1 - 3.1 8.5 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain SPOC PF07744.13 KFM70455.1 - 8.1e-27 94.0 0.0 1.7e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 SPOC domain HTH_Tnp_Tc3_2 PF01498.18 KFM70456.1 - 8.2e-11 42.0 2.9 1.4e-10 41.3 2.9 1.4 1 0 0 1 1 1 1 Transposase Kelch_1 PF01344.25 KFM70457.1 - 2.7e-12 46.0 1.7 1.8e-05 24.2 0.0 3.8 3 2 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KFM70457.1 - 2.8e-09 36.9 0.3 0.0019 18.2 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM70457.1 - 6.3e-08 32.6 1.6 0.0043 17.3 0.0 3.8 3 2 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 KFM70457.1 - 7.5e-08 32.2 0.0 0.0039 17.1 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KFM70457.1 - 2e-07 30.7 0.0 0.27 11.3 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 KFM70457.1 - 0.00047 20.4 0.0 1 9.7 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Ion_trans_2 PF07885.16 KFM70458.1 - 1.1e-19 70.1 2.2 1.7e-19 69.6 2.2 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFM70458.1 - 0.0084 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein zf-LITAF-like PF10601.9 KFM70458.1 - 0.042 14.1 0.2 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF5641 PF18701.1 KFM70459.1 - 3e-21 75.4 0.0 4.3e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) HTH_Tnp_Tc3_2 PF01498.18 KFM70460.1 - 2.6e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70460.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70460.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70460.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70460.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM70461.1 - 2.1e-16 59.9 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70461.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM70462.1 - 4.6e-07 29.7 0.0 8.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease KTI12 PF08433.10 KFM70463.1 - 1e-10 41.5 3.4 1.8e-10 40.7 3.4 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KFM70463.1 - 0.001 19.4 0.3 0.0056 17.1 0.0 2.3 2 1 1 3 3 3 1 RNA helicase AAA_33 PF13671.6 KFM70463.1 - 0.0048 17.1 0.6 0.083 13.0 0.6 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM70463.1 - 0.0063 17.1 3.9 0.041 14.4 0.3 3.2 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KFM70463.1 - 0.04 14.0 0.1 0.13 12.3 0.0 1.9 2 1 2 4 4 4 0 AAA domain Zeta_toxin PF06414.12 KFM70463.1 - 0.064 12.5 0.0 0.41 9.9 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 KFM70463.1 - 0.99 8.8 8.5 1.3 8.4 1.4 3.2 2 1 1 3 3 3 0 Poxvirus A32 protein TUDOR PF00567.24 KFM70465.1 - 3.3e-09 36.8 0.2 3.9e-09 36.6 0.2 1.1 1 0 0 1 1 1 1 Tudor domain OST-HTH PF12872.7 KFM70466.1 - 4.1e-22 77.8 2.0 1.9e-12 46.8 0.2 3.3 3 0 0 3 3 3 3 OST-HTH/LOTUS domain RL PF17797.1 KFM70466.1 - 0.11 12.5 0.7 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 RL domain Nop53 PF07767.11 KFM70467.1 - 0.13 11.6 0.0 0.15 11.5 0.0 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Glyco_hydro_20 PF00728.22 KFM70469.1 - 2e-20 73.5 0.2 3.7e-20 72.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KFM70469.1 - 5.6e-20 72.4 0.0 7.2e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like BRCA-2_OB3 PF09104.10 KFM70469.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 TPT PF03151.16 KFM70470.1 - 1.2e-19 70.8 17.8 1.5e-19 70.4 17.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM70470.1 - 1.4e-07 31.8 34.2 3.1e-05 24.2 12.2 2.7 2 1 0 2 2 2 2 EamA-like transporter family HTH_Tnp_Tc3_2 PF01498.18 KFM70471.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70471.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70471.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70471.1 - 0.0027 17.5 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70471.1 - 0.029 14.5 0.4 0.091 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM70471.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF3094 PF11293.8 KFM70472.1 - 0.058 13.1 0.1 0.08 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Tmemb_14 PF03647.13 KFM70473.1 - 5.7e-27 94.3 10.8 6.5e-27 94.1 10.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C FHA PF00498.26 KFM70474.1 - 4.7e-15 55.7 0.0 8.4e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain AAA_11 PF13086.6 KFM70475.1 - 1.3e-59 202.1 0.6 1.3e-59 202.1 0.6 3.4 2 2 0 2 2 1 1 AAA domain AAA_12 PF13087.6 KFM70475.1 - 7.5e-54 182.4 0.0 7.5e-54 182.4 0.0 3.3 4 0 0 4 4 4 1 AAA domain R3H PF01424.22 KFM70475.1 - 2.2e-15 56.4 0.5 7.3e-15 54.7 0.5 2.0 1 0 0 1 1 1 1 R3H domain AAA_30 PF13604.6 KFM70475.1 - 1.2e-11 44.7 0.0 4.5e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFM70475.1 - 2e-09 37.9 0.1 1e-08 35.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KFM70475.1 - 2.9e-06 27.4 0.0 4.8e-05 23.4 0.0 2.6 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit zf-AN1 PF01428.16 KFM70475.1 - 7.4e-06 26.0 15.0 7.4e-06 26.0 15.0 1.8 2 0 0 2 2 1 1 AN1-like Zinc finger Viral_helicase1 PF01443.18 KFM70475.1 - 0.00026 20.8 7.4 0.63 9.7 0.0 4.7 5 0 0 5 5 5 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KFM70475.1 - 0.00027 20.7 1.8 0.0022 17.8 0.3 2.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.6 KFM70475.1 - 0.00055 20.4 0.0 0.0021 18.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.14 KFM70475.1 - 0.00085 19.2 0.6 0.14 12.0 0.0 3.8 4 0 0 4 4 4 1 Helicase Flavi_DEAD PF07652.14 KFM70475.1 - 0.0024 17.8 0.6 0.011 15.7 0.1 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA PF00004.29 KFM70475.1 - 0.0038 17.7 0.6 0.017 15.6 0.6 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM70475.1 - 0.0052 17.1 0.0 0.019 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFM70475.1 - 0.0059 15.7 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 KFM70475.1 - 0.0089 15.5 0.1 0.021 14.3 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.6 KFM70475.1 - 0.0098 15.5 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFM70475.1 - 0.034 13.7 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD_C_2 PF13538.6 KFM70475.1 - 0.041 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 KFM70475.1 - 0.047 13.7 0.4 0.75 9.8 0.0 3.1 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFM70475.1 - 0.072 12.5 0.2 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFM70475.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFM70475.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain FG-GAP PF01839.23 KFM70475.1 - 0.16 12.1 0.2 0.33 11.1 0.2 1.5 1 0 0 1 1 1 0 FG-GAP repeat NTPase_1 PF03266.15 KFM70475.1 - 0.16 11.9 3.4 4.7 7.1 0.2 3.5 3 1 0 3 3 3 0 NTPase ABC_tran PF00005.27 KFM70475.1 - 0.25 11.9 0.0 0.25 11.9 0.0 3.1 2 1 0 3 3 3 0 ABC transporter Transp_Tc5_C PF04236.15 KFM70475.1 - 1.2 9.5 11.8 4 7.9 11.8 1.9 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain 7tm_1 PF00001.21 KFM70476.1 - 5.7 6.2 9.0 9.5 5.5 9.0 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) HTH_Tnp_Tc3_2 PF01498.18 KFM70477.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70477.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70477.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70477.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70477.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain KH_1 PF00013.29 KFM70478.1 - 2.3e-09 36.9 1.0 3.8e-09 36.2 0.4 1.7 2 0 0 2 2 2 1 KH domain RRM_1 PF00076.22 KFM70478.1 - 3e-08 33.3 0.0 4.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.17 KFM70478.1 - 0.0033 17.2 0.0 0.013 15.3 0.1 1.8 2 0 0 2 2 2 1 KH domain KH_5 PF13184.6 KFM70478.1 - 0.14 12.3 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 NusA-like KH domain zf-H2C2_2 PF13465.6 KFM70479.1 - 6.2e-67 219.2 51.4 8.9e-10 38.6 0.5 9.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM70479.1 - 4.8e-40 133.8 71.4 1.5e-06 28.3 3.0 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70479.1 - 7.1e-32 107.3 67.0 0.00028 21.5 1.5 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM70479.1 - 4e-23 81.0 66.0 4e-05 23.8 1.8 8.4 8 0 0 8 8 8 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM70479.1 - 1.3e-15 56.9 57.3 0.0024 17.8 1.1 8.7 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM70479.1 - 1.1e-12 47.8 48.4 0.0076 16.5 0.6 8.4 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM70479.1 - 7.6e-12 44.8 45.8 0.022 14.5 0.2 8.7 9 0 0 9 9 9 6 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM70479.1 - 4.7e-06 26.5 28.9 1.7 8.7 0.4 8.0 5 3 3 8 8 8 3 Sec23/Sec24 zinc finger BolA PF01722.18 KFM70479.1 - 1.7e-05 25.0 11.5 0.74 10.1 0.4 5.2 1 1 5 6 6 6 2 BolA-like protein zf-C2H2_9 PF16293.5 KFM70479.1 - 0.00015 21.5 34.2 2 8.3 0.1 8.0 2 2 6 8 8 8 3 C2H2 type zinc-finger (1 copy) TRAF6_Z2 PF18048.1 KFM70479.1 - 0.0013 18.7 46.8 0.87 9.7 0.6 8.3 8 1 0 8 8 8 3 TNF receptor-associated factor 6 zinc finger 2 GAGA PF09237.11 KFM70479.1 - 0.0074 16.1 19.7 1.2 9.1 0.2 6.2 1 1 6 7 7 7 1 GAGA factor C1_4 PF07975.12 KFM70479.1 - 0.015 15.5 3.7 0.015 15.5 3.7 5.0 2 2 3 5 5 5 0 TFIIH C1-like domain zf-C2H2_2 PF12756.7 KFM70479.1 - 0.018 15.4 58.9 0.24 11.8 1.2 7.7 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM70479.1 - 0.034 14.1 18.7 4.3 7.4 0.3 5.4 2 2 3 5 5 5 0 Adenylate kinase, active site lid C5HCH PF17982.1 KFM70479.1 - 0.28 11.4 37.7 2.1 8.5 1.2 8.0 6 2 2 8 8 8 0 NSD Cys-His rich domain Zf_RING PF16744.5 KFM70479.1 - 0.29 11.3 39.6 2.5 8.3 0.5 7.5 1 1 6 7 7 7 0 KIAA1045 RING finger FYVE PF01363.21 KFM70479.1 - 0.5 10.5 46.6 2.8 8.2 2.8 4.9 1 1 4 5 5 5 0 FYVE zinc finger zf-CHCC PF10276.9 KFM70479.1 - 2.1 8.5 11.9 62 3.8 0.0 6.0 8 0 0 8 8 6 0 Zinc-finger domain zf-RRPl_C4 PF17026.5 KFM70479.1 - 3 8.0 34.5 6.6 6.9 8.7 4.2 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2HC_2 PF13913.6 KFM70479.1 - 3.6 7.6 38.8 0.97 9.4 0.1 7.9 8 1 0 8 8 8 0 zinc-finger of a C2HC-type zf-FPG_IleRS PF06827.14 KFM70479.1 - 5 7.1 18.7 13 5.7 0.1 5.9 6 0 0 6 6 6 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 KFM70479.1 - 8.4 6.6 30.7 8.9 6.5 0.8 5.1 2 2 2 5 5 5 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 KFM70480.1 - 1e-51 171.1 58.3 6.1e-09 35.9 1.4 8.7 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM70480.1 - 2.5e-36 122.1 68.7 7e-06 26.2 1.0 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70480.1 - 1.9e-25 87.4 65.4 0.00041 20.9 0.6 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM70480.1 - 3e-14 52.9 56.3 0.00042 20.6 0.9 8.2 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM70480.1 - 1e-10 41.6 36.3 0.0015 18.8 0.2 7.8 8 0 0 8 8 7 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM70480.1 - 2.1e-10 40.2 33.9 0.039 13.7 0.3 8.5 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM70480.1 - 5.5e-10 39.0 63.0 0.014 15.4 0.3 9.4 9 0 0 9 9 9 7 C2H2-type zinc finger BolA PF01722.18 KFM70480.1 - 1.2e-08 35.1 3.8 0.014 15.7 0.0 5.3 1 1 5 6 6 6 2 BolA-like protein Tox-HNH-HHH PF15637.6 KFM70480.1 - 2.2e-05 24.5 0.4 2.6 8.2 0.0 4.1 1 1 4 5 5 5 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-CHCC PF10276.9 KFM70480.1 - 0.00052 20.0 7.6 28 4.9 0.0 6.2 7 0 0 7 7 7 0 Zinc-finger domain zf-MYST PF17772.1 KFM70480.1 - 0.0021 17.6 28.6 0.76 9.4 0.2 6.8 1 1 6 7 7 7 3 MYST family zinc finger domain zf-DBF PF07535.12 KFM70480.1 - 0.0045 17.1 27.5 3.2 7.9 0.1 7.3 7 0 0 7 7 7 1 DBF zinc finger GAGA PF09237.11 KFM70480.1 - 0.011 15.5 20.8 4.3 7.2 0.1 6.4 1 1 6 7 7 7 0 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM70480.1 - 0.012 15.7 19.5 2.9 8.0 0.2 6.6 5 2 2 7 7 7 0 Sec23/Sec24 zinc finger DUF2256 PF10013.9 KFM70480.1 - 0.045 13.9 28.3 9.2 6.5 0.1 7.2 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-FPG_IleRS PF06827.14 KFM70480.1 - 0.069 13.0 19.1 13 5.8 0.1 6.1 7 0 0 7 7 6 0 Zinc finger found in FPG and IleRS zf-C2H2_9 PF16293.5 KFM70480.1 - 0.11 12.4 27.7 7.5 6.5 0.1 7.5 2 2 6 8 8 8 0 C2H2 type zinc-finger (1 copy) TRAF6_Z2 PF18048.1 KFM70480.1 - 0.13 12.4 43.0 1 9.5 0.1 8.0 8 0 0 8 8 8 0 TNF receptor-associated factor 6 zinc finger 2 FYVE PF01363.21 KFM70480.1 - 0.22 11.7 35.5 0.8 9.9 2.7 4.0 1 1 0 3 3 3 0 FYVE zinc finger Prok-RING_1 PF14446.6 KFM70480.1 - 0.29 11.1 29.4 19 5.3 0.1 7.2 6 1 0 6 6 6 0 Prokaryotic RING finger family 1 zf-RRPl_C4 PF17026.5 KFM70480.1 - 0.36 10.9 24.4 1.8 8.7 6.7 3.5 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2HC_2 PF13913.6 KFM70480.1 - 1.7 8.7 0.0 1.7 8.7 0.0 7.1 7 0 0 7 7 6 0 zinc-finger of a C2HC-type VGCC_alpha2 PF08473.11 KFM70480.1 - 1.9 7.1 7.7 0.78 8.5 0.6 2.2 1 1 1 2 2 2 0 Neuronal voltage-dependent calcium channel alpha 2acd zf-C2H2_2 PF12756.7 KFM70480.1 - 9.7 6.6 51.2 2.3 8.6 0.4 7.7 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) LIM PF00412.22 KFM70482.1 - 5.5e-32 109.8 20.6 3.5e-16 59.2 8.6 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFM70482.1 - 1.8e-19 69.3 4.7 2.7e-19 68.7 4.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM70482.1 - 2e-05 24.4 0.1 4e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFM70482.1 - 0.0072 15.8 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez TNFR_c6 PF00020.18 KFM70482.1 - 6.4 7.3 12.3 7.2 7.1 1.3 3.7 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region TMEM52 PF14979.6 KFM70483.1 - 3.1e-05 23.9 2.3 0.052 13.5 0.0 2.3 1 1 1 2 2 2 2 Transmembrane 52 Tox-ART-HYD1 PF15633.6 KFM70483.1 - 0.11 13.2 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 HYD1 signature containing ADP-ribosyltransferase BTG PF07742.12 KFM70485.1 - 1.2e-40 138.0 0.0 3.5e-40 136.5 0.0 1.7 2 0 0 2 2 2 1 BTG family Tim17 PF02466.19 KFM70486.1 - 7.6e-28 97.1 4.2 9.4e-28 96.8 4.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.6 KFM70486.1 - 0.098 12.5 13.6 0.9 9.4 8.3 2.7 2 0 0 2 2 2 0 Glycine-zipper domain STALD PF18185.1 KFM70486.1 - 0.19 11.0 0.4 0.25 10.7 0.4 1.2 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family MULE PF10551.9 KFM70488.1 - 8.8e-09 35.7 0.0 1.1e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 MULE transposase domain Pkinase PF00069.25 KFM70489.1 - 8.8e-70 235.1 0.1 1.3e-69 234.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 KFM70489.1 - 2.3e-42 143.0 1.1 5.4e-23 81.0 0.4 2.9 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 KFM70489.1 - 1.1e-37 129.7 0.0 1.7e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM70489.1 - 1.6e-06 27.6 0.0 3.6e-05 23.2 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFM70489.1 - 8.5e-05 21.5 0.1 0.00012 21.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM70489.1 - 0.02 13.9 0.8 0.033 13.1 0.8 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFM70489.1 - 0.036 13.4 0.2 0.26 10.6 0.1 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Endopep_inhib PF16800.5 KFM70489.1 - 0.04 13.9 0.3 0.12 12.3 0.3 1.8 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor IRF PF00605.17 KFM70490.1 - 2.2e-08 34.3 1.8 2.4e-08 34.2 1.8 1.0 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Ets PF00178.22 KFM70490.1 - 0.00026 21.4 1.9 0.0003 21.2 1.9 1.2 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFM70490.1 - 0.15 12.0 2.5 0.15 12.0 1.4 1.6 1 1 1 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain HTH_Tnp_Tc3_2 PF01498.18 KFM70491.1 - 3.9e-16 59.0 3.5 5.8e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70491.1 - 1.3e-13 51.0 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70491.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70491.1 - 0.0027 17.5 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70491.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-C2H2_4 PF13894.6 KFM70492.1 - 2.1e-08 34.3 26.6 0.021 15.6 0.3 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM70492.1 - 0.00027 21.2 26.2 0.86 10.2 4.4 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-CRD PF17979.1 KFM70492.1 - 0.0004 20.5 14.3 0.29 11.2 4.6 4.0 1 1 1 2 2 2 2 Cysteine rich domain with multizinc binding regions Yippee-Mis18 PF03226.14 KFM70492.1 - 0.0059 16.8 7.8 0.025 14.8 0.5 3.0 1 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_2 PF12756.7 KFM70492.1 - 0.0087 16.4 12.5 0.019 15.3 4.3 2.8 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFM70492.1 - 0.009 16.4 23.6 1.3 9.5 2.3 4.9 4 1 0 4 4 4 2 Zinc-finger of C2H2 type C1_2 PF03107.16 KFM70492.1 - 0.17 12.3 15.3 1.9 8.9 0.1 4.3 3 1 1 4 4 4 0 C1 domain VATC PF18716.1 KFM70492.1 - 0.28 11.0 15.1 6.6 6.7 0.1 4.3 4 0 0 4 4 4 0 Vms1-associating treble clef domain zf-C2H2_3rep PF18868.1 KFM70492.1 - 0.61 10.8 10.2 28 5.4 0.1 3.7 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-AN1 PF01428.16 KFM70492.1 - 1 9.6 15.1 20 5.4 0.1 4.4 4 0 0 4 4 4 0 AN1-like Zinc finger zf-B_box PF00643.24 KFM70492.1 - 1.1 9.5 13.8 2.1 8.6 0.6 4.1 4 0 0 4 4 4 0 B-box zinc finger zf-C3HC PF07967.13 KFM70492.1 - 1.4 9.0 13.9 4.1 7.4 0.3 4.0 3 1 1 4 4 4 0 C3HC zinc finger-like zf_UBZ PF18439.1 KFM70492.1 - 1.9 8.1 14.8 5 6.8 0.1 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger LIM PF00412.22 KFM70492.1 - 3.3 8.0 18.2 33 4.8 1.0 4.2 4 0 0 4 4 4 0 LIM domain zf-CRD PF17979.1 KFM70493.1 - 8.8e-05 22.7 12.4 0.047 13.8 4.6 2.6 1 1 1 2 2 2 2 Cysteine rich domain with multizinc binding regions zf-C2H2_4 PF13894.6 KFM70493.1 - 0.00062 20.4 14.7 0.2 12.6 3.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM70493.1 - 0.00079 19.8 15.5 0.056 13.9 4.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Tox-HNH-HHH PF15637.6 KFM70493.1 - 0.16 12.1 0.9 0.67 10.1 0.2 2.2 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-met PF12874.7 KFM70493.1 - 0.19 12.1 15.6 2.1 8.8 4.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-B_box PF00643.24 KFM70493.1 - 0.33 11.2 11.3 0.63 10.2 1.5 2.4 2 0 0 2 2 2 0 B-box zinc finger zf-C2H2_3rep PF18868.1 KFM70493.1 - 0.48 11.1 5.6 6.4 7.5 0.3 2.9 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-AN1 PF01428.16 KFM70493.1 - 0.71 10.1 10.4 1.6 9.0 1.0 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger C5HCH PF17982.1 KFM70493.1 - 0.89 9.8 7.9 6.8 6.9 0.9 2.7 2 0 0 2 2 2 0 NSD Cys-His rich domain zf-C2H2_jaz PF12171.8 KFM70493.1 - 0.97 9.8 21.3 3.5 8.0 6.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.22 KFM70494.1 - 1.9e-39 133.3 0.1 1.2e-20 73.1 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM70494.1 - 1.8e-05 24.3 0.0 0.0095 15.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM70494.1 - 0.0016 18.3 0.0 0.0036 17.1 0.0 1.6 1 1 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFM70494.1 - 0.0041 17.2 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 Limkain b1 RRM_3 PF08777.11 KFM70494.1 - 0.049 13.7 0.0 9.3 6.4 0.0 2.8 2 2 0 2 2 2 0 RNA binding motif RNA_bind PF08675.11 KFM70494.1 - 0.12 12.4 0.0 1.8 8.6 0.0 2.6 3 1 0 3 3 3 0 RNA binding domain Glyco_tran_10_N PF17039.5 KFM70495.1 - 4e-26 91.6 1.0 4e-26 91.6 1.0 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal OSK PF17182.4 KFM70495.1 - 0.078 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 OSK domain Trypsin PF00089.26 KFM70496.1 - 7.4e-49 166.5 0.8 9.2e-49 166.2 0.8 1.1 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFM70496.1 - 1.5e-07 31.7 0.0 3.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 CUB domain Trypsin_2 PF13365.6 KFM70496.1 - 2.6e-07 31.7 0.0 5.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ldl_recept_a PF00057.18 KFM70496.1 - 1e-05 25.6 14.9 3.1e-05 24.1 14.9 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 KFM70496.1 - 0.0007 20.0 0.0 0.0021 18.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) zf-TAZ PF02135.16 KFM70496.1 - 1.1 9.8 4.6 2.2 8.8 0.8 2.3 2 0 0 2 2 2 0 TAZ zinc finger KH_6 PF15985.5 KFM70497.1 - 1.2e-08 35.2 0.1 1.8e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 KFM70498.1 - 1e-13 50.8 0.0 1.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 KFM70498.1 - 0.018 15.6 1.4 0.31 11.7 0.3 2.2 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 CAML PF14963.6 KFM70499.1 - 2.7e-05 24.4 11.9 0.00011 22.4 11.9 2.0 1 1 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand DUF3776 PF12618.8 KFM70499.1 - 0.21 12.2 6.4 1.9 9.1 4.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3776) HTH_Tnp_Tc3_2 PF01498.18 KFM70501.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70501.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70501.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70501.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70501.1 - 2.1 9.0 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM70502.1 - 5e-16 58.7 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70502.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70502.1 - 6.7e-08 32.2 1.9 1.6e-07 31.0 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70502.1 - 0.0027 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70502.1 - 3.2 8.4 16.4 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain MAM PF00629.23 KFM70503.1 - 3.1e-13 49.9 3.7 1.2e-12 48.1 0.0 2.8 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu Somatomedin_B PF01033.17 KFM70503.1 - 4.3e-07 30.2 17.5 6.7e-07 29.6 17.5 1.3 1 0 0 1 1 1 1 Somatomedin B domain DUF4748 PF15932.5 KFM70503.1 - 0.0039 16.9 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) DUF4366 PF14283.6 KFM70503.1 - 0.49 10.4 0.0 0.49 10.4 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) HTH_Tnp_Tc3_2 PF01498.18 KFM70504.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Transposase DUF1835 PF08874.10 KFM70504.1 - 0.24 11.6 2.0 0.31 11.2 1.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1835) DDE_Tnp_IS1595 PF12762.7 KFM70505.1 - 8e-07 29.2 0.0 1.5e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 ISXO2-like transposase domain DUF2946 PF11162.8 KFM70506.1 - 0.055 14.1 7.1 0.065 13.9 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) SelP_N PF04592.14 KFM70506.1 - 3.7 6.9 9.5 4.6 6.6 9.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2946 PF11162.8 KFM70507.1 - 0.052 14.2 4.0 0.061 14.0 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) SelP_N PF04592.14 KFM70507.1 - 3.2 7.1 9.3 4.2 6.7 9.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HTH_Tnp_Tc3_2 PF01498.18 KFM70509.1 - 2.4e-16 59.7 2.2 4.3e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70509.1 - 2.3e-13 50.2 0.0 3.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease STAG PF08514.11 KFM70510.1 - 4.6e-41 139.3 0.4 2.3e-40 137.0 0.4 2.3 1 0 0 1 1 1 1 STAG domain Prismane PF03063.20 KFM70510.1 - 0.011 14.4 0.8 0.66 8.6 0.5 2.9 3 0 0 3 3 3 0 Prismane/CO dehydrogenase family TIMELESS PF04821.14 KFM70511.1 - 3.1e-42 144.8 3.8 3.5e-42 144.6 3.8 1.0 1 0 0 1 1 1 1 Timeless protein Dpy-30 PF05186.13 KFM70511.1 - 0.075 12.7 0.0 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 Dpy-30 motif TIMELESS_C PF05029.13 KFM70512.1 - 1.1e-66 226.2 101.4 1.2e-55 189.8 16.0 6.1 4 1 3 7 7 7 4 Timeless protein C terminal region HrcA_DNA-bdg PF03444.15 KFM70512.1 - 0.081 12.6 0.2 0.31 10.7 0.2 2.0 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_27 PF13463.6 KFM70512.1 - 7 7.2 14.4 5.3 7.6 0.3 4.9 6 0 0 6 6 6 0 Winged helix DNA-binding domain RT_RNaseH_2 PF17919.1 KFM70513.1 - 3.1e-33 113.8 0.0 5.5e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM70513.1 - 4.8e-31 107.2 0.0 8.3e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Spectrin PF00435.21 KFM70514.1 - 1.9e-281 912.2 184.4 4.9e-21 75.2 6.7 17.4 17 0 0 17 17 17 17 Spectrin repeat CH PF00307.31 KFM70514.1 - 1.4e-48 163.5 2.8 6.5e-25 87.4 0.0 4.2 4 0 0 4 4 4 2 Calponin homology (CH) domain PH_9 PF15410.6 KFM70514.1 - 6.5e-20 71.7 0.6 6.5e-20 71.7 0.6 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KFM70514.1 - 5.5e-13 49.3 1.7 2.2e-12 47.4 0.2 2.9 3 0 0 3 3 3 1 PH domain CAMSAP_CH PF11971.8 KFM70514.1 - 6e-08 32.4 0.1 4.9e-06 26.3 0.0 3.0 2 0 0 2 2 2 1 CAMSAP CH domain DUF2498 PF10692.9 KFM70514.1 - 0.1 12.5 0.7 1.5 8.8 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2498) PGK PF00162.19 KFM70514.1 - 0.33 9.9 3.6 0.21 10.5 0.6 2.1 2 0 0 2 2 2 0 Phosphoglycerate kinase CnrY PF17524.2 KFM70514.1 - 1.7 8.9 9.0 8.1 6.7 0.2 4.3 5 0 0 5 5 5 0 Anti-sigma factor CnrY Myb_DNA-binding PF00249.31 KFM70515.1 - 3.9e-16 59.0 0.0 8e-09 35.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain ELM2 PF01448.24 KFM70515.1 - 3.2e-11 43.8 0.1 1e-10 42.2 0.1 1.9 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 KFM70515.1 - 6.7e-08 32.3 1.3 0.00077 19.3 0.1 2.6 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KFM70515.1 - 0.00066 19.9 0.1 0.13 12.5 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain MSA-2c PF12238.8 KFM70515.1 - 0.023 14.7 1.7 0.066 13.2 0.2 2.5 3 0 0 3 3 3 0 Merozoite surface antigen 2c GATA PF00320.27 KFM70515.1 - 0.031 13.9 4.6 0.067 12.8 4.6 1.6 1 0 0 1 1 1 0 GATA zinc finger I-set PF07679.16 KFM70517.1 - 3.2e-29 100.8 0.2 9.3e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM70517.1 - 2.6e-25 88.8 1.3 2.9e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM70517.1 - 9e-20 70.7 0.6 2.4e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM70517.1 - 1e-18 67.4 0.3 1.1e-09 38.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 KFM70517.1 - 2.9e-08 34.0 0.1 0.00058 20.2 0.1 2.4 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 KFM70517.1 - 2.9e-08 33.8 4.0 0.0045 17.1 0.6 3.5 2 2 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM70517.1 - 3.1e-05 23.9 0.4 0.036 14.1 0.1 2.5 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM70517.1 - 0.00056 20.2 0.3 0.24 11.8 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFM70517.1 - 0.00062 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 C17orf99 Ig domain Ig_6 PF18452.1 KFM70517.1 - 0.0094 15.5 0.1 0.068 12.7 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 KFM70517.1 - 0.022 15.0 0.1 2.4 8.5 0.0 2.7 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 KFM70517.1 - 0.022 14.5 0.6 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Izumo-Ig PF16706.5 KFM70517.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFM70517.1 - 0.099 12.6 0.9 0.32 11.0 0.9 1.8 1 1 0 1 1 1 0 CD47 immunoglobulin-like domain I-set PF07679.16 KFM70518.1 - 1.3e-48 162.9 1.0 1.5e-15 57.0 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM70518.1 - 6.4e-42 142.0 6.3 2.1e-15 57.1 0.0 5.0 5 0 0 5 5 4 3 Immunoglobulin domain fn3 PF00041.21 KFM70518.1 - 7.5e-39 132.0 17.8 3.7e-16 59.2 0.8 4.9 4 1 0 4 4 4 3 Fibronectin type III domain Ig_2 PF13895.6 KFM70518.1 - 1.3e-29 102.4 2.1 6.3e-10 39.3 0.1 4.0 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFM70518.1 - 2.4e-29 101.4 3.1 2.5e-09 37.2 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFM70518.1 - 2.1e-10 40.8 8.8 1.9e-05 24.8 0.0 5.5 4 3 0 4 4 3 2 Immunoglobulin V-set domain Interfer-bind PF09294.10 KFM70518.1 - 1.5e-07 31.7 0.0 0.013 15.8 0.0 3.5 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Ig_6 PF18452.1 KFM70518.1 - 8.2e-07 28.5 0.0 0.66 9.6 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 KFM70518.1 - 8.8e-06 26.0 0.3 1 9.8 0.1 3.9 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFM70518.1 - 2.4e-05 24.6 2.0 0.34 11.3 0.1 3.5 4 0 0 4 4 4 2 Immunoglobulin C1-set domain C2-set_2 PF08205.12 KFM70518.1 - 2.4e-05 24.3 0.3 0.061 13.4 0.1 3.6 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM70518.1 - 4.4e-05 23.5 0.0 0.68 10.0 0.0 3.8 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM70518.1 - 0.00029 21.3 11.9 0.029 14.9 0.2 4.6 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 KFM70518.1 - 0.00047 20.1 0.0 4.4 7.4 0.0 3.8 2 1 1 3 3 3 1 C17orf99 Ig domain Myotub-related PF06602.14 KFM70519.1 - 2.5e-129 431.2 0.0 3.2e-129 430.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain 3-PAP PF12578.8 KFM70519.1 - 0.0072 16.1 0.3 0.014 15.1 0.3 1.4 1 0 0 1 1 1 1 Myotubularin-associated protein Hydrolase_6 PF13344.6 KFM70519.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CAMP_factor PF07373.11 KFM70520.1 - 0.0027 17.3 0.2 0.0029 17.3 0.2 1.0 1 0 0 1 1 1 1 CAMP factor (Cfa) FANCI_S1 PF14675.6 KFM70522.1 - 0.018 14.6 0.3 0.023 14.3 0.3 1.3 1 1 0 1 1 1 0 FANCI solenoid 1 MOR2-PAG1_C PF14225.6 KFM70522.1 - 0.072 12.9 0.8 0.23 11.3 0.3 1.8 2 0 0 2 2 2 0 Cell morphogenesis C-terminal DHC_N1 PF08385.12 KFM70525.1 - 0.00013 20.8 0.0 0.14 10.8 0.0 2.1 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 Rota_NS6 PF04866.12 KFM70525.1 - 0.0052 17.0 0.0 0.011 15.9 0.0 1.5 2 0 0 2 2 2 1 Rotavirus non-structural protein 6 DHC_N1 PF08385.12 KFM70526.1 - 1.4e-08 33.9 0.4 1.5e-08 33.8 0.4 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 F1F0-ATPsyn_F PF10791.9 KFM70526.1 - 0.1 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi DHC_N2 PF08393.13 KFM70528.1 - 4.3e-43 147.9 1.3 4.7e-43 147.8 1.3 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 KFM70529.1 - 1.2e-120 402.5 0.1 1.4e-120 402.2 0.1 1.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 KFM70529.1 - 4e-05 23.6 0.0 0.001 19.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFM70529.1 - 0.00096 18.9 0.1 0.0026 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFM70529.1 - 0.023 15.1 0.0 0.075 13.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Katanin_con80 PF13925.6 KFM70529.1 - 0.039 14.0 0.2 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 con80 domain of Katanin DUF613 PF04764.12 KFM70529.1 - 0.19 11.8 3.0 0.16 12.1 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF613) AAA_7 PF12775.7 KFM70531.1 - 4.8e-13 49.0 0.0 8.6e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_1 PF17857.1 KFM70531.1 - 0.022 15.0 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA+ lid domain DUF4478 PF14793.6 KFM70532.1 - 0.011 15.6 0.5 0.011 15.6 0.5 1.0 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases MIT_C PF16565.5 KFM70532.1 - 0.096 12.7 1.3 0.1 12.6 1.3 1.1 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT DUF5453 PF17534.2 KFM70532.1 - 0.19 11.6 0.3 0.2 11.6 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) Atg14 PF10186.9 KFM70532.1 - 0.81 8.7 5.6 0.77 8.8 5.6 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MT PF12777.7 KFM70533.1 - 0.0042 16.2 0.2 0.0048 16.0 0.2 1.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 KFM70534.1 - 2.8e-54 183.6 4.6 3.3e-54 183.4 4.6 1.1 1 0 0 1 1 1 1 ATP-binding dynein motor region MAT1 PF06391.13 KFM70534.1 - 0.02 14.7 1.3 0.027 14.3 1.3 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Dynein_C PF18199.1 KFM70535.1 - 3.3e-42 144.8 0.0 4.9e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KFM70535.1 - 4.1e-40 137.3 0.0 7e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KFM70535.1 - 2e-32 111.8 0.2 4.5e-32 110.6 0.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain V-SNARE_C PF12352.8 KFM70536.1 - 1.7e-14 53.8 3.2 1.7e-14 53.8 3.2 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KFM70536.1 - 3.4e-14 53.0 2.2 3.4e-14 53.0 2.2 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 KFM70536.1 - 0.00055 19.8 1.8 0.00055 19.8 1.8 3.1 2 2 1 3 3 3 1 Sec20 GCP_N_terminal PF17681.1 KFM70536.1 - 0.0088 15.7 0.3 0.015 14.9 0.2 1.4 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal Cir_Bir_Yir PF06022.11 KFM70536.1 - 0.0094 15.5 0.9 0.012 15.1 0.9 1.4 1 1 0 1 1 1 1 Plasmodium variant antigen protein Cir/Yir/Bir DUF4407 PF14362.6 KFM70536.1 - 0.015 14.6 5.6 0.024 14.0 5.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PRKCSH PF07915.13 KFM70536.1 - 0.19 12.8 0.0 0.35 11.9 0.0 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Phage_GPO PF05929.11 KFM70536.1 - 0.22 11.1 4.2 0.095 12.3 0.7 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.15 KFM70536.1 - 0.23 11.0 9.5 0.44 10.1 9.5 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fusion_gly PF00523.18 KFM70536.1 - 0.28 9.4 4.9 0.087 11.1 1.5 1.8 1 1 0 2 2 2 0 Fusion glycoprotein F0 DUF3376 PF11856.8 KFM70536.1 - 0.8 8.6 6.3 0.26 10.2 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3376) EzrA PF06160.12 KFM70536.1 - 1.1 7.3 16.4 0.0043 15.3 5.5 2.3 2 1 0 2 2 1 0 Septation ring formation regulator, EzrA Syntaxin-6_N PF09177.11 KFM70536.1 - 1.3 9.6 5.7 28 5.3 5.7 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HIP1_clath_bdg PF16515.5 KFM70536.1 - 2.5 8.7 9.1 1.4 9.6 2.7 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SKA2 PF16740.5 KFM70536.1 - 3 7.7 7.2 6.5 6.6 0.0 3.5 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Sec8_exocyst PF04048.14 KFM70536.1 - 4.2 7.3 8.9 17 5.3 0.2 2.7 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DDE_3 PF13358.6 KFM70537.1 - 3.3e-10 39.9 0.0 4.6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70537.1 - 3.5e-07 30.4 0.2 7.3e-07 29.3 0.2 1.5 1 0 0 1 1 1 1 Transposase AMP-binding PF00501.28 KFM70538.1 - 0.003 16.2 0.0 0.004 15.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Put_Phosphatase PF06888.12 KFM70538.1 - 0.056 12.8 0.1 0.08 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative Phosphatase AMP-binding PF00501.28 KFM70539.1 - 1.4e-35 122.7 0.0 1.7e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM70539.1 - 7.2e-08 32.2 4.1 7.2e-08 32.2 4.1 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM70540.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70540.1 - 1.3e-12 47.6 0.0 2.4e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70540.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70540.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70540.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain AMP-binding PF00501.28 KFM70541.1 - 3.4e-43 147.8 0.0 4.8e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM70541.1 - 1e-08 35.0 4.0 2.2e-08 33.9 4.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KFM70541.1 - 0.0015 19.4 0.0 0.0053 17.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM70542.1 - 2.5e-16 59.7 2.2 4.4e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70542.1 - 9.7e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease WAP PF00095.21 KFM70543.1 - 8e-05 23.0 9.8 0.00011 22.6 9.8 1.2 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' KCNQC3-Ank-G_bd PF11956.8 KFM70543.1 - 0.15 12.3 0.1 0.17 12.2 0.1 1.2 1 1 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 Kri1 PF05178.12 KFM70546.1 - 0.025 15.1 0.1 0.029 14.9 0.1 1.1 1 0 0 1 1 1 0 KRI1-like family zf-RRN7 PF11781.8 KFM70547.1 - 1.1e-05 25.0 4.2 1.6e-05 24.5 4.2 1.2 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 KFM70547.1 - 0.0042 16.6 1.3 0.0076 15.7 1.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding PHF5 PF03660.14 KFM70547.1 - 0.03 14.5 0.5 0.043 14.0 0.5 1.3 1 0 0 1 1 1 0 PHF5-like protein DZR PF12773.7 KFM70547.1 - 0.058 13.4 1.1 0.074 13.1 0.5 1.6 2 0 0 2 2 2 0 Double zinc ribbon zf-RRPl_C4 PF17026.5 KFM70547.1 - 0.085 13.0 1.2 0.11 12.6 0.7 1.5 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2318 PF10080.9 KFM70547.1 - 0.086 13.0 2.5 0.16 12.1 2.5 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) MqsA_antitoxin PF15731.5 KFM70547.1 - 0.098 12.8 1.7 1.3 9.1 0.2 2.4 2 1 1 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA C1_2 PF03107.16 KFM70547.1 - 0.44 10.9 3.0 0.76 10.1 3.0 1.4 1 0 0 1 1 1 0 C1 domain JAB PF01398.21 KFM70548.1 - 1.7e-22 79.6 0.6 2.3e-22 79.2 0.6 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFM70548.1 - 0.12 12.8 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Myb_DNA-bind_5 PF13873.6 KFM70549.1 - 1.7e-16 60.0 3.9 2.3e-16 59.6 3.9 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFM70549.1 - 0.053 13.9 2.1 0.081 13.3 2.1 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 KFM70550.1 - 1.6e-27 96.1 0.0 1.8e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM70550.1 - 7.5e-07 29.0 0.0 1.7e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFM70550.1 - 0.0019 17.9 0.3 0.044 13.4 0.0 2.0 1 1 1 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 KFM70550.1 - 0.16 12.4 0.5 0.27 11.6 0.5 1.6 1 1 0 1 1 1 0 Transposase DDE domain LRRNT PF01462.18 KFM70552.1 - 5e-05 22.9 0.8 7.4e-05 22.3 0.8 1.3 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Lip_prot_lig_C PF10437.9 KFM70552.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus LRR_8 PF13855.6 KFM70553.1 - 3e-40 135.8 83.7 6.9e-12 44.9 7.8 6.6 3 1 6 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 KFM70553.1 - 8.3e-15 54.7 39.2 9.3e-05 22.7 5.5 6.8 3 2 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM70553.1 - 1.6e-13 50.7 17.2 3.6e-08 33.4 3.2 4.3 2 2 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 KFM70553.1 - 1e-10 42.1 0.2 6.7e-10 39.4 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM70553.1 - 7.8e-10 38.7 0.0 8.8e-09 35.3 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM70553.1 - 1.5e-06 28.5 0.1 9.4e-05 22.7 0.1 2.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM70553.1 - 2.2e-06 27.7 0.0 9.7e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 KFM70553.1 - 0.00073 19.1 2.8 0.00073 19.1 2.8 4.1 2 2 3 5 5 5 3 Leucine-rich repeat V-set PF07686.17 KFM70553.1 - 0.0015 18.7 0.0 0.0048 17.1 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_1 PF00560.33 KFM70553.1 - 0.017 15.6 31.6 20 6.3 0.2 9.6 8 2 0 8 8 8 0 Leucine Rich Repeat Suppressor_P21 PF11479.8 KFM70553.1 - 0.82 9.9 7.8 6.6 7.0 0.6 3.6 1 1 1 3 3 3 0 RNA silencing suppressor P21 C-terminal domain LRR_6 PF13516.6 KFM70553.1 - 1 9.6 32.5 1.9 8.7 0.1 8.1 7 1 1 8 8 8 0 Leucine Rich repeat TAF6_C PF07571.13 KFM70553.1 - 1.8 9.0 4.6 5 7.5 1.4 3.2 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Phage_Mu_Gam PF07352.12 KFM70553.1 - 5.4 6.9 7.6 2.6e+02 1.5 7.6 2.4 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Exonuc_VII_L PF02601.15 KFM70553.1 - 7.3 6.1 9.4 14 5.2 9.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit BRCA2 PF00634.18 KFM70556.1 - 2.1e-08 33.7 2.6 2.7e-08 33.4 0.1 2.5 3 0 0 3 3 3 1 BRCA2 repeat Vinculin PF01044.19 KFM70557.1 - 1.2e-21 76.8 0.1 1.4e-21 76.6 0.1 1.0 1 0 0 1 1 1 1 Vinculin family zf-TFIIIC PF12660.7 KFM70557.1 - 0.13 12.2 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex YtxH PF12732.7 KFM70558.1 - 1e-05 26.0 0.8 0.0051 17.3 0.8 2.4 1 1 0 1 1 1 1 YtxH-like protein 4HB_MCP_1 PF12729.7 KFM70558.1 - 0.027 14.0 0.4 0.24 10.9 0.3 2.0 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Vinculin PF01044.19 KFM70559.1 - 1.1e-21 76.9 0.6 1.3e-21 76.7 0.6 1.0 1 0 0 1 1 1 1 Vinculin family AA_permease_2 PF13520.6 KFM70560.1 - 1.3e-36 126.4 15.9 1.4e-36 126.3 15.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM70560.1 - 1.2e-20 73.6 13.8 1.5e-20 73.3 13.8 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 KFM70560.1 - 0.00066 18.8 14.1 0.001 18.2 14.1 1.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family TcpE PF12648.7 KFM70560.1 - 0.43 11.2 0.2 0.43 11.2 0.2 2.8 3 0 0 3 3 3 0 TcpE family AA_permease_2 PF13520.6 KFM70561.1 - 0.00026 20.0 3.5 0.00027 19.9 3.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2475 PF10629.9 KFM70562.1 - 5.5e-16 58.5 5.4 0.017 15.3 0.1 5.1 4 1 1 5 5 5 4 Protein of unknown function (DUF2475) TERF2_RBM PF16772.5 KFM70562.1 - 0.027 13.9 0.2 0.082 12.3 0.0 1.9 2 0 0 2 2 2 0 Telomeric repeat-binding factor 2 Rap1-binding motif MRP-S34 PF16053.5 KFM70562.1 - 0.11 12.2 0.3 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S34 HTH_Tnp_Tc3_2 PF01498.18 KFM70563.1 - 1.7e-13 50.6 2.1 2.6e-13 50.0 1.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70563.1 - 3.1e-09 36.7 0.0 2.7e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Ion_trans PF00520.31 KFM70563.1 - 9.3e-05 21.8 1.7 0.00013 21.3 1.7 1.2 1 0 0 1 1 1 1 Ion transport protein HTH_IclR PF09339.10 KFM70563.1 - 0.00046 19.9 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF962 PF06127.11 KFM70563.1 - 0.0038 17.3 1.0 0.0094 16.0 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF962) HTH_23 PF13384.6 KFM70563.1 - 0.05 13.4 0.1 0.17 11.8 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM70563.1 - 0.059 14.0 0.2 0.059 14.0 0.2 3.4 1 1 2 3 3 3 0 Homeodomain-like domain HTH_31 PF13560.6 KFM70563.1 - 0.26 11.7 4.5 0.36 11.2 2.6 2.3 1 1 0 1 1 1 0 Helix-turn-helix domain BNIP3 PF06553.12 KFM70564.1 - 2.6e-45 154.5 5.7 6.6e-45 153.2 5.7 1.5 1 1 0 1 1 1 1 BNIP3 Sarcoglycan_1 PF04790.13 KFM70565.1 - 2.6e-53 181.0 0.0 3.1e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein Exo_endo_phos_2 PF14529.6 KFM70567.1 - 0.012 15.4 0.1 0.013 15.3 0.1 1.1 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Kelch_1 PF01344.25 KFM70568.1 - 1.8e-29 101.0 1.2 4.9e-15 54.8 0.1 2.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 KFM70568.1 - 6.9e-17 61.1 0.1 8.2e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 KFM70568.1 - 2.4e-10 40.0 0.3 0.00098 19.0 0.3 2.6 2 1 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 KFM70568.1 - 7e-09 35.6 1.0 0.0003 20.7 0.0 2.3 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KFM70568.1 - 3.2e-08 33.7 0.0 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain BACK PF07707.15 KFM70569.1 - 8e-27 93.4 0.1 1.9e-26 92.2 0.0 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 KFM70569.1 - 2.4e-23 81.4 0.4 7.2e-15 54.3 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 KFM70569.1 - 1.9e-14 53.3 0.5 8.8e-10 38.5 0.0 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.15 KFM70569.1 - 3.2e-09 36.4 1.4 1.4e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 KFM70569.1 - 6.3e-09 35.7 1.4 1.2e-05 25.2 0.0 2.3 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KFM70569.1 - 6.3e-07 29.5 0.1 0.014 15.7 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM70569.1 - 0.00034 20.5 0.0 0.2 11.7 0.0 2.5 2 0 0 2 2 2 2 Kelch motif HTH_Tnp_Tc3_2 PF01498.18 KFM70570.1 - 4.9e-16 58.7 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70570.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70570.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70570.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70570.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM70571.1 - 2.4e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70571.1 - 9.4e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease TraD_N PF12615.8 KFM70572.1 - 0.11 13.3 1.0 0.11 13.3 1.0 1.6 2 0 0 2 2 2 0 F sex factor protein N terminal TUDOR_5 PF18359.1 KFM70573.1 - 2.9e-27 94.1 1.1 4.1e-26 90.4 0.2 3.1 3 0 0 3 3 3 1 Histone methyltransferase Tudor domain 1 Tudor_4 PF18358.1 KFM70573.1 - 7.3e-19 67.1 2.2 9.1e-17 60.4 0.3 2.4 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain Tudor_3 PF18115.1 KFM70573.1 - 0.0016 18.3 1.0 2.2 8.2 0.0 3.2 3 0 0 3 3 3 2 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 KFM70573.1 - 0.22 12.0 1.2 1.6 9.3 0.0 2.9 4 0 0 4 4 4 0 Agenet domain HTH_Tnp_Tc3_2 PF01498.18 KFM70576.1 - 2.2e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70576.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Sushi PF00084.20 KFM70577.1 - 4.4e-06 27.2 2.1 0.003 18.1 0.2 2.6 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Cnd1 PF12717.7 KFM70579.1 - 8e-10 39.0 0.0 9.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HTH_Tnp_Tc3_2 PF01498.18 KFM70581.1 - 2.2e-16 59.8 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70581.1 - 9.7e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease FERM_N PF09379.10 KFM70582.1 - 7e-14 51.5 0.3 9.5e-14 51.1 0.3 1.2 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 KFM70583.1 - 0.0021 18.5 0.0 0.0021 18.5 0.0 1.0 1 0 0 1 1 1 1 FERM central domain Y_phosphatase PF00102.27 KFM70585.1 - 7.4e-75 251.5 0.2 1e-74 251.1 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PDZ PF00595.24 KFM70585.1 - 1.5e-19 70.1 0.0 3.2e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain FA PF08736.11 KFM70585.1 - 2.9e-15 56.1 5.7 6.5e-15 54.9 5.7 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) PDZ_6 PF17820.1 KFM70585.1 - 1e-07 31.7 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain FERM_C PF09380.10 KFM70585.1 - 5.4e-05 23.5 1.0 0.00065 20.0 0.2 2.5 2 0 0 2 2 2 1 FERM C-terminal PH-like domain Y_phosphatase3 PF13350.6 KFM70585.1 - 0.00047 20.2 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFM70585.1 - 0.00068 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFM70585.1 - 0.012 15.8 0.1 0.26 11.4 0.0 2.5 2 1 0 2 2 2 0 Inositol hexakisphosphate PDZ_2 PF13180.6 KFM70585.1 - 0.023 15.0 0.0 0.059 13.7 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Como_SCP PF02248.16 KFM70585.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Small coat protein COX16 PF14138.6 KFM70586.1 - 1e-23 83.6 0.1 1.4e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Peptidase_M1 PF01433.20 KFM70587.1 - 4.7e-14 52.5 1.1 1e-13 51.3 0.5 2.0 2 1 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFM70587.1 - 2.5e-05 24.6 0.3 0.00016 21.9 0.1 2.4 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 KFM70587.1 - 0.00022 21.6 0.0 0.09 13.2 0.0 3.2 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.22 KFM70587.1 - 0.0017 18.4 0.4 21 5.7 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat FBA_2 PF07735.17 KFM70587.1 - 0.055 13.6 0.3 0.16 12.1 0.3 1.8 1 0 0 1 1 1 0 F-box associated DUF2457 PF10446.9 KFM70587.1 - 0.7 9.0 10.6 1.1 8.3 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Homeodomain PF00046.29 KFM70588.1 - 6.5e-24 83.5 5.2 1.4e-23 82.5 5.0 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFM70588.1 - 0.0056 16.6 0.3 0.013 15.3 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFM70588.1 - 0.07 12.6 0.9 0.087 12.3 0.0 1.6 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez HAUS-augmin3 PF14932.6 KFM70589.1 - 0.023 14.3 0.7 0.023 14.3 0.7 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 SPO22 PF08631.10 KFM70589.1 - 0.074 12.5 0.2 0.074 12.5 0.2 1.0 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like 4HB_MCP_1 PF12729.7 KFM70590.1 - 0.042 13.4 0.4 0.065 12.8 0.3 1.5 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction Vmethyltransf PF01660.17 KFM70590.1 - 0.08 11.8 0.0 0.08 11.8 0.0 1.0 1 0 0 1 1 1 0 Viral methyltransferase TPR_1 PF00515.28 KFM70590.1 - 0.16 11.8 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM70590.1 - 0.2 11.8 0.3 0.48 10.7 0.3 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat SNF2_N PF00176.23 KFM70592.1 - 1.6e-38 132.3 0.5 2.2e-37 128.6 0.5 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KFM70592.1 - 5.4e-11 42.8 0.0 1e-10 41.9 0.0 1.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KFM70592.1 - 6.7e-06 25.2 0.0 9.2e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 KFM70592.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KFM70592.1 - 0.00029 20.6 0.0 0.00064 19.5 0.0 1.6 1 1 0 1 1 1 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 KFM70592.1 - 0.068 13.2 0.0 0.19 11.7 0.0 1.7 1 1 1 2 2 2 0 AAA domain Peptidase_A17 PF05380.13 KFM70593.1 - 5.6e-31 107.7 0.2 1.8e-30 106.1 0.2 1.9 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 KFM70593.1 - 5.2e-29 101.1 0.1 2e-28 99.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF5641 PF18701.1 KFM70593.1 - 1e-18 67.3 3.2 3.3e-18 65.6 3.2 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1758 PF05585.12 KFM70593.1 - 2.7e-16 59.8 0.1 1.8e-15 57.1 0.0 2.4 2 0 0 2 2 2 1 Putative peptidase (DUF1758) rve PF00665.26 KFM70593.1 - 2.1e-14 53.7 0.1 6e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KFM70593.1 - 6.6e-09 35.6 0.2 3.6e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KFM70593.1 - 1.6e-07 31.3 2.5 1.6e-07 31.3 2.5 2.8 3 0 0 3 3 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 KFM70593.1 - 0.017 15.7 0.0 0.071 13.8 0.0 2.1 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.6 KFM70593.1 - 0.046 13.5 0.0 0.49 10.2 0.0 2.6 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH_2 PF17919.1 KFM70593.1 - 0.099 12.7 0.0 0.46 10.5 0.0 2.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-CCHC_4 PF14392.6 KFM70593.1 - 0.56 10.0 5.1 7.7 6.3 1.0 2.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KFM70593.1 - 1.1 9.2 14.9 0.034 14.0 1.3 2.9 3 0 0 3 3 3 0 Zinc knuckle zf-H2C2 PF09337.10 KFM70593.1 - 4.6 7.5 8.8 0.091 13.0 0.9 2.5 2 0 0 2 2 1 0 H2C2 zinc finger HobA PF12163.8 KFM70594.1 - 0.68 9.5 6.1 7.8 6.0 0.6 2.4 2 0 0 2 2 2 0 DNA replication regulator EMP24_GP25L PF01105.24 KFM70595.1 - 2.6e-50 170.9 0.1 3.9e-50 170.3 0.1 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 KFM70595.1 - 0.0034 17.6 0.2 0.0067 16.6 0.2 1.5 1 1 0 1 1 1 1 SdrD B-like domain YcbB PF08664.10 KFM70595.1 - 0.038 14.0 0.1 0.059 13.4 0.1 1.2 1 0 0 1 1 1 0 YcbB domain Snapin_Pallidin PF14712.6 KFM70595.1 - 0.05 14.0 0.3 0.084 13.3 0.3 1.3 1 0 0 1 1 1 0 Snapin/Pallidin TerD PF02342.18 KFM70595.1 - 0.075 12.5 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 TerD domain Elong_Iki1 PF10483.9 KFM70595.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 Peptidase_M23 PF01551.22 KFM70595.1 - 0.089 13.0 0.3 0.22 11.8 0.1 1.9 1 1 0 1 1 1 0 Peptidase family M23 HDAC4_Gln PF12203.8 KFM70595.1 - 0.096 12.9 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 DEAD PF00270.29 KFM70596.1 - 2.1e-31 109.0 0.0 3.4e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM70596.1 - 1e-28 99.8 0.4 4.6e-28 97.8 0.1 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM70596.1 - 8.2e-06 25.9 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFM70596.1 - 0.007 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 KFM70596.1 - 0.057 12.6 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Cobalamin_bind PF01122.19 KFM70597.1 - 6.4e-26 91.0 0.7 7.9e-23 80.8 0.3 2.1 2 0 0 2 2 2 2 Eukaryotic cobalamin-binding protein Ldl_recept_a PF00057.18 KFM70597.1 - 6.2e-09 35.9 7.5 6.2e-09 35.9 7.5 1.7 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFM70597.1 - 0.00083 19.7 1.3 0.002 18.5 1.3 1.6 1 0 0 1 1 1 1 CUB domain DUF4430 PF14478.6 KFM70597.1 - 0.099 13.3 0.1 0.27 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) EGF PF00008.27 KFM70600.1 - 1.6e-70 232.9 285.3 1e-06 28.9 9.6 20.0 19 1 0 19 19 19 16 EGF-like domain EGF_2 PF07974.13 KFM70600.1 - 4.8e-19 68.4 305.5 0.0082 16.5 7.2 20.0 18 3 2 20 20 20 16 EGF-like domain hEGF PF12661.7 KFM70600.1 - 1.4e-09 38.2 232.3 0.011 16.4 3.9 22.0 21 1 0 21 21 21 13 Human growth factor-like EGF GluR_Homer-bdg PF10606.9 KFM70600.1 - 0.081 13.1 1.6 0.23 11.7 0.3 2.6 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor AMP-binding PF00501.28 KFM70604.1 - 1e-101 340.6 0.0 1.3e-101 340.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM70604.1 - 3.2e-19 69.7 0.0 2.5e-18 66.8 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Glyco_hydro2_C5 PF18565.1 KFM70604.1 - 0.04 13.7 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 Myelin_PLP PF01275.19 KFM70606.1 - 7.1e-28 98.1 7.6 7.8e-28 97.9 7.6 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) Phage_holin_3_6 PF07332.11 KFM70606.1 - 0.97 9.5 5.6 1.3 9.1 5.6 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DHHC PF01529.20 KFM70606.1 - 1.5 8.9 7.2 1.8 8.6 7.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Myelin_PLP PF01275.19 KFM70607.1 - 2.1e-08 34.4 12.2 3.1e-08 33.8 12.2 1.3 1 1 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) Presenilin PF01080.17 KFM70607.1 - 0.056 12.2 1.8 0.056 12.2 1.8 1.0 1 0 0 1 1 1 0 Presenilin p450 PF00067.22 KFM70608.1 - 1.5e-96 323.9 0.0 1.8e-96 323.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.6 KFM70609.1 - 6.5e-16 58.4 0.1 5.7e-15 55.3 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70609.1 - 7.7e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM70609.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70609.1 - 0.0026 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70609.1 - 0.016 15.3 0.1 0.065 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM70609.1 - 0.034 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM70610.1 - 2.8e-16 59.5 2.0 6.1e-16 58.4 2.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70610.1 - 4.7e-11 42.6 0.0 8.4e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 KFM70610.1 - 0.0058 16.7 4.6 0.027 14.6 0.0 3.2 1 1 3 4 4 4 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM70610.1 - 0.032 13.7 0.3 3 7.3 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 KFM70610.1 - 0.078 13.0 1.9 0.15 12.1 0.0 2.3 2 1 0 2 2 2 0 Winged helix-turn helix Spt4 PF06093.13 KFM70611.1 - 3e-08 33.6 0.1 3.6e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger SASP PF00269.20 KFM70613.1 - 0.0026 17.8 1.3 0.004 17.1 1.3 1.4 1 0 0 1 1 1 1 Small, acid-soluble spore proteins, alpha/beta type Mto2_bdg PF12808.7 KFM70613.1 - 0.027 14.7 2.6 0.039 14.3 2.6 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HTH_Tnp_Tc3_2 PF01498.18 KFM70614.1 - 4.5e-16 58.8 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70614.1 - 2.8e-13 49.8 0.0 4.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70614.1 - 1.6e-07 30.9 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70614.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70614.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RAM PF15320.6 KFM70615.1 - 2.3e-12 47.3 16.0 2.3e-12 47.3 16.0 2.1 1 1 1 2 2 2 1 mRNA cap methylation, RNMT-activating mini protein Presenilin PF01080.17 KFM70615.1 - 7.8 5.1 4.6 8.5 5.0 4.6 1.0 1 0 0 1 1 1 0 Presenilin Ion_trans_N PF08412.10 KFM70616.1 - 2.3e-26 91.1 0.1 4.8e-26 90.1 0.1 1.5 2 0 0 2 2 2 1 Ion transport protein N-terminal PID_2 PF14719.6 KFM70617.1 - 7.5e-06 25.9 0.1 0.0074 16.2 0.1 2.3 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) Rpp20 PF12328.8 KFM70617.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P CAP_N PF01213.19 KFM70617.1 - 2.8 7.4 12.2 0.054 13.0 1.5 2.5 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal HTH_Tnp_Tc3_2 PF01498.18 KFM70620.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70620.1 - 8.4e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70622.1 - 5.5e-16 58.6 3.5 6e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70622.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70622.1 - 2.2e-07 30.5 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70622.1 - 0.0029 17.3 0.6 0.008 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70622.1 - 0.027 14.6 0.4 0.095 12.8 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM70622.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain EGF PF00008.27 KFM70624.1 - 3.4e-13 49.6 63.7 6.9e-08 32.7 9.1 11.7 9 4 0 10 10 10 6 EGF-like domain hEGF PF12661.7 KFM70624.1 - 5.6e-05 23.6 17.8 0.0015 19.0 6.8 12.2 10 1 0 10 10 10 5 Human growth factor-like EGF Coatomer_WDAD PF04053.14 KFM70627.1 - 1.6e-170 567.9 0.1 2.5e-170 567.3 0.1 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KFM70627.1 - 7.8e-42 140.5 4.8 2.5e-07 31.3 0.0 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM70627.1 - 7.4e-08 32.6 0.3 2.3 8.6 0.0 6.3 3 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KFM70627.1 - 0.00051 20.0 0.1 3 7.9 0.0 4.3 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KFM70627.1 - 0.038 13.3 0.1 4.8 6.4 0.0 3.2 2 1 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 KFM70627.1 - 0.26 9.9 2.3 10 4.6 0.0 3.6 1 1 2 4 4 4 0 Nucleoporin Nup120/160 Complex1_LYR PF05347.15 KFM70629.1 - 8e-12 45.0 0.0 8.9e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFM70629.1 - 0.00013 22.7 0.0 0.00014 22.6 0.0 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Frag1 PF10277.9 KFM70630.1 - 4.3e-39 134.3 21.4 5.1e-39 134.1 21.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SH3_9 PF14604.6 KFM70631.1 - 9.6e-34 115.0 0.3 1.1e-16 60.3 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFM70631.1 - 4.9e-29 99.7 2.2 8.1e-14 51.0 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KFM70631.1 - 5.4e-25 86.8 0.1 4.8e-12 45.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Fib_alpha PF08702.10 KFM70631.1 - 5.3 7.2 9.7 0.3 11.3 1.3 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family COMM_domain PF07258.14 KFM70632.1 - 8.9e-15 54.6 0.6 1.5e-14 53.8 0.6 1.3 1 0 0 1 1 1 1 COMM domain Sld5 PF05916.11 KFM70632.1 - 0.066 13.7 0.1 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 GINS complex protein DUF3827 PF12877.7 KFM70634.1 - 5.2e-08 31.7 10.1 2.5e-05 22.9 0.0 3.1 2 1 0 3 3 3 2 Domain of unknown function (DUF3827) Shisa PF13908.6 KFM70634.1 - 0.011 16.0 1.7 0.031 14.5 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF3481 PF11980.8 KFM70634.1 - 0.031 14.0 1.1 0.061 13.0 1.1 1.4 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Adeno_E3_CR2 PF02439.15 KFM70634.1 - 0.43 10.4 5.3 0.88 9.4 5.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FAM176 PF14851.6 KFM70634.1 - 8.1 6.1 5.7 5.5 6.6 0.0 2.4 2 1 0 2 2 2 0 FAM176 family NGP1NT PF08153.12 KFM70637.1 - 7.1e-49 165.3 0.2 1.7e-48 164.1 0.2 1.7 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KFM70637.1 - 1.4e-17 63.8 0.0 3.2e-13 49.7 0.0 3.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM70637.1 - 6.3e-06 25.8 0.1 4.1e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM70637.1 - 3.2e-05 23.9 0.0 0.00012 22.0 0.0 2.0 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 KFM70637.1 - 0.00015 21.3 0.2 0.22 11.0 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KFM70637.1 - 0.023 14.9 0.2 10 6.3 0.0 4.0 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_C47 PF05543.13 KFM70637.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 DUF3894 PF13033.6 KFM70638.1 - 0.0072 16.4 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3894) ANAPC2 PF08672.11 KFM70638.1 - 0.028 14.9 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 Topoisom_bac PF01131.20 KFM70639.1 - 1.3e-79 268.2 0.0 1.6e-79 267.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase HypA PF01155.19 KFM70639.1 - 0.23 11.5 0.1 0.23 11.5 0.1 3.3 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Toprim PF01751.22 KFM70640.1 - 1.3e-19 70.3 0.0 1.8e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Toprim domain Topoisom_bac PF01131.20 KFM70640.1 - 0.00026 20.1 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase NUP50 PF08911.11 KFM70641.1 - 1.7e-12 47.8 0.1 1.7e-12 47.8 0.1 2.9 3 0 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KFM70641.1 - 5.7e-05 23.4 0.0 0.00037 20.7 0.0 2.2 2 0 0 2 2 2 1 RanBP1 domain PHD PF00628.29 KFM70643.1 - 3.8e-09 36.3 7.5 6.3e-09 35.6 7.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KFM70643.1 - 0.074 13.2 3.4 0.068 13.3 1.7 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain DUF3450 PF11932.8 KFM70643.1 - 0.12 11.7 3.1 0.17 11.2 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RCDG1 PF15725.5 KFM70643.1 - 0.13 12.7 7.6 0.44 11.0 4.5 2.2 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein zf-HIT PF04438.16 KFM70643.1 - 2.1 8.3 5.9 0.88 9.5 0.4 2.7 3 0 0 3 3 3 0 HIT zinc finger His_Phos_1 PF00300.22 KFM70645.1 - 2.3e-10 40.5 3.2 4.7e-06 26.4 0.0 5.0 4 1 1 5 5 5 2 Histidine phosphatase superfamily (branch 1) Vac_Fusion PF02346.16 KFM70645.1 - 0.0089 15.6 1.6 3.9 7.2 0.1 3.5 2 0 0 2 2 2 2 Chordopoxvirus multifunctional envelope protein A27 NYD-SP28_assoc PF14775.6 KFM70645.1 - 0.099 12.8 0.1 8.5 6.6 0.1 2.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain DNA_ligase_A_N PF04675.14 KFM70645.1 - 1.4 9.2 12.2 0.032 14.6 1.1 3.3 2 1 0 2 2 2 0 DNA ligase N terminus His_Phos_1 PF00300.22 KFM70646.1 - 1.1e-13 51.3 0.0 2.5e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF5315 PF17242.2 KFM70647.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) Transferase PF02458.15 KFM70647.1 - 0.098 11.3 0.1 0.098 11.3 0.1 1.0 1 0 0 1 1 1 0 Transferase family 7tm_1 PF00001.21 KFM70648.1 - 2.4e-12 46.8 1.9 3.7e-12 46.1 1.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFM70648.1 - 0.00095 19.0 3.2 0.0012 18.6 3.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFM70648.1 - 0.0036 17.0 4.8 0.0036 17.0 4.8 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx RGS PF00615.19 KFM70649.1 - 2.7e-30 105.0 0.5 2.7e-30 105.0 0.5 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain PDZ PF00595.24 KFM70649.1 - 1.1e-14 54.6 0.0 2.9e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM70649.1 - 4.3e-12 45.7 0.1 9.4e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PID PF00640.23 KFM70649.1 - 1.7e-05 24.9 0.0 0.00011 22.2 0.0 2.4 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ_2 PF13180.6 KFM70649.1 - 0.00035 20.8 0.0 0.0014 18.9 0.0 2.0 1 0 0 1 1 1 1 PDZ domain Tnp_P_element PF12017.8 KFM70650.1 - 2.7e-06 27.0 0.1 4.3e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Transposase protein Mg_trans_NIPA PF05653.14 KFM70652.1 - 1.5e-21 76.8 1.8 1.7e-21 76.6 1.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA Mg_trans_NIPA PF05653.14 KFM70653.1 - 1.8e-60 204.5 14.7 2.2e-60 204.3 14.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF5383 PF17355.2 KFM70653.1 - 1.2 9.5 0.0 1.2 9.5 0.0 2.7 3 1 0 3 3 3 0 Family of unknown function (DUF5383) Lzipper-MIP1 PF14389.6 KFM70654.1 - 0.023 15.0 5.6 0.061 13.6 0.5 2.6 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 NPA PF16469.5 KFM70654.1 - 0.17 12.4 0.0 0.27 11.8 0.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF3024 PF11225.8 KFM70655.1 - 0.0075 16.5 0.9 0.016 15.5 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3024) Somatomedin_B PF01033.17 KFM70655.1 - 0.0098 16.3 8.4 0.0098 16.3 8.4 2.8 3 0 0 3 3 3 1 Somatomedin B domain DHOR PF06537.11 KFM70655.1 - 0.15 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase Somatomedin_B PF01033.17 KFM70656.1 - 0.0043 17.4 11.0 0.0043 17.4 11.0 2.4 2 0 0 2 2 2 1 Somatomedin B domain SP24 PF16504.5 KFM70657.1 - 0.0067 16.4 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative virion membrane protein of plant and insect virus Somatomedin_B PF01033.17 KFM70658.1 - 0.0017 18.7 10.1 0.0017 18.7 10.1 3.1 3 0 0 3 3 3 1 Somatomedin B domain Somatomedin_B PF01033.17 KFM70659.1 - 0.00067 20.0 9.7 0.00067 20.0 9.7 3.4 4 0 0 4 4 4 1 Somatomedin B domain HTH_Tnp_Tc3_2 PF01498.18 KFM70660.1 - 5.8e-11 42.5 0.6 1e-10 41.7 0.6 1.4 1 0 0 1 1 1 1 Transposase HTH_3 PF01381.22 KFM70660.1 - 0.00041 20.3 0.7 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix HTH_32 PF13565.6 KFM70660.1 - 0.00054 20.5 4.6 0.00059 20.4 1.8 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM70660.1 - 0.003 17.4 0.5 0.34 10.8 0.0 2.5 1 1 1 2 2 2 1 MarR family HTH_28 PF13518.6 KFM70660.1 - 0.0039 17.3 0.9 0.25 11.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM70660.1 - 0.006 16.5 1.9 0.075 13.0 0.1 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KFM70660.1 - 0.016 15.0 2.3 0.25 11.2 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain HTH_20 PF12840.7 KFM70660.1 - 0.025 14.6 0.1 0.51 10.4 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 KFM70660.1 - 0.027 14.9 0.3 2.3 8.7 0.2 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 KFM70660.1 - 0.04 13.5 1.0 1.5 8.4 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding FUR PF01475.19 KFM70660.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family Somatomedin_B PF01033.17 KFM70661.1 - 0.00029 21.2 9.5 0.00029 21.2 9.5 3.2 4 0 0 4 4 4 1 Somatomedin B domain Somatomedin_B PF01033.17 KFM70662.1 - 0.00066 20.0 8.9 0.00066 20.0 8.9 3.4 4 0 0 4 4 4 1 Somatomedin B domain DUF4969 PF16339.5 KFM70662.1 - 0.087 13.2 0.2 0.18 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) Somatomedin_B PF01033.17 KFM70663.1 - 0.00061 20.1 11.0 0.00061 20.1 11.0 3.1 4 0 0 4 4 4 1 Somatomedin B domain TPR_MLP1_2 PF07926.12 KFM70664.1 - 8.5e-28 97.0 26.4 8.5e-28 97.0 26.4 9.1 4 2 5 10 10 10 4 TPR/MLP1/MLP2-like protein Cnn_1N PF07989.11 KFM70664.1 - 0.00039 20.5 3.6 0.00039 20.5 3.6 10.9 5 5 4 9 9 9 1 Centrosomin N-terminal motif 1 Pox_A_type_inc PF04508.12 KFM70664.1 - 0.25 11.3 7.5 0.057 13.3 0.4 4.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat HTH_Tnp_Tc3_2 PF01498.18 KFM70665.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70665.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2_4 PF13894.6 KFM70667.1 - 0.015 16.1 19.4 0.037 14.9 2.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM70667.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 KFM70667.1 - 0.13 11.5 5.1 0.14 11.3 5.1 1.2 1 0 0 1 1 1 0 Putative actin-like family Elf1 PF05129.13 KFM70667.1 - 0.18 11.9 7.2 0.33 11.0 3.3 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like C1_1 PF00130.22 KFM70667.1 - 0.24 11.3 11.4 0.49 10.3 6.4 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.6 KFM70667.1 - 0.52 10.8 18.1 3.2 8.3 0.5 3.4 3 1 0 3 3 3 0 Zinc-finger double domain DUF629 PF04780.12 KFM70667.1 - 0.65 8.5 11.9 0.91 8.0 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 KFM70668.1 - 1.1e-11 44.5 17.0 0.0096 16.3 1.7 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70668.1 - 1.9e-07 31.3 20.9 0.25 12.3 0.1 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger ADK_lid PF05191.14 KFM70668.1 - 0.00027 20.9 2.7 0.0005 20.0 0.2 2.2 2 0 0 2 2 2 1 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 KFM70668.1 - 0.00028 21.0 4.1 0.27 11.4 0.2 2.5 2 1 0 2 2 2 2 Zinc ribbon domain DZR PF12773.7 KFM70668.1 - 0.0014 18.6 5.9 0.008 16.2 2.9 2.5 2 1 1 3 3 3 1 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KFM70668.1 - 0.0056 16.2 0.7 4.6 6.8 0.0 3.0 3 0 0 3 3 3 1 TFIIB zinc-binding zinc_ribbon_15 PF17032.5 KFM70668.1 - 0.0058 17.4 3.2 0.031 15.0 3.2 2.0 1 1 0 1 1 1 1 zinc-ribbon family zf_UBZ PF18439.1 KFM70668.1 - 0.02 14.5 4.5 3.9 7.2 0.1 3.5 4 0 0 4 4 3 0 Ubiquitin-Binding Zinc Finger zf-HIT PF04438.16 KFM70668.1 - 0.055 13.4 4.9 15 5.6 0.0 3.3 3 0 0 3 3 3 0 HIT zinc finger XPA_N PF01286.18 KFM70668.1 - 0.06 13.4 3.9 3.7 7.7 0.1 3.2 3 0 0 3 3 3 0 XPA protein N-terminal zf-Mss51 PF13824.6 KFM70668.1 - 0.063 13.4 5.9 2.2 8.5 1.2 2.8 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Rtf2 PF04641.12 KFM70668.1 - 0.064 12.6 0.5 0.21 10.9 0.5 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger C1_4 PF07975.12 KFM70668.1 - 0.09 13.0 7.1 0.82 9.9 2.1 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain Methyltransf_13 PF08421.11 KFM70668.1 - 0.092 13.0 1.6 0.42 10.9 0.2 2.2 1 1 1 2 2 2 0 Putative zinc binding domain zinc-ribbons_6 PF07191.12 KFM70668.1 - 0.22 11.5 4.9 14 5.7 4.9 2.5 1 1 0 1 1 1 0 zinc-ribbons Cas_CXXC_CXXC PF09706.10 KFM70668.1 - 0.29 11.4 4.1 6.3 7.1 0.1 3.1 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) Rpr2 PF04032.16 KFM70668.1 - 0.44 10.9 3.8 0.95 9.8 3.8 1.6 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_10 PF10058.9 KFM70668.1 - 0.48 10.2 7.5 3.2 7.6 1.8 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein FYVE PF01363.21 KFM70668.1 - 0.5 10.6 7.0 7.7 6.7 6.9 2.6 1 1 1 2 2 2 0 FYVE zinc finger C1_2 PF03107.16 KFM70668.1 - 2.1 8.8 9.8 6.7 7.1 1.6 3.1 1 1 0 2 2 2 0 C1 domain zf-C2H2_11 PF16622.5 KFM70668.1 - 3 7.7 11.9 0.93 9.3 0.4 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-AN1 PF01428.16 KFM70668.1 - 5.2 7.3 9.3 18 5.6 0.2 3.7 3 1 1 4 4 4 0 AN1-like Zinc finger Ldl_recept_a PF00057.18 KFM70669.1 - 1.1e-06 28.7 7.3 3e-06 27.3 7.3 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Rogdi_lz PF10259.9 KFM70671.1 - 0.00079 19.0 0.0 0.00086 18.8 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein DUF1987 PF09345.10 KFM70672.1 - 0.063 13.0 0.2 0.074 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) EamA PF00892.20 KFM70674.1 - 0.00039 20.6 0.7 0.00046 20.4 0.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family Renin_r PF07850.14 KFM70674.1 - 0.0027 18.3 0.0 0.0035 17.9 0.0 1.2 1 0 0 1 1 1 1 Renin receptor-like protein THAP PF05485.12 KFM70675.1 - 1.2e-17 64.6 4.5 1.2e-17 64.6 4.5 1.9 2 1 0 2 2 2 1 THAP domain Ada_Zn_binding PF02805.16 KFM70675.1 - 0.12 12.4 2.8 0.31 11.1 1.9 2.0 2 0 0 2 2 2 0 Metal binding domain of Ada DUF1759 PF03564.15 KFM70677.1 - 5.8e-25 88.0 0.0 7.1e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) PriX PF18689.1 KFM70677.1 - 0.14 12.5 0.2 0.28 11.6 0.2 1.4 1 0 0 1 1 1 0 Primase X PHD PF00628.29 KFM70678.1 - 1.2e-08 34.7 6.6 2.7e-08 33.6 6.6 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KFM70678.1 - 0.023 14.6 3.4 0.023 14.6 3.4 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 KFM70678.1 - 0.049 14.0 0.7 0.049 14.0 0.7 2.6 3 0 0 3 3 3 0 C1 domain zf-RING_2 PF13639.6 KFM70678.1 - 0.06 13.7 3.9 0.06 13.7 3.9 1.8 1 1 0 1 1 1 0 Ring finger domain Excalibur PF05901.11 KFM70678.1 - 0.13 12.9 0.0 0.42 11.3 0.0 1.9 2 0 0 2 2 2 0 Excalibur calcium-binding domain zf-PHD-like PF15446.6 KFM70678.1 - 0.17 11.5 2.6 0.33 10.5 2.6 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RING_11 PF17123.5 KFM70678.1 - 0.68 9.7 6.1 1.6 8.5 6.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger PHD_2 PF13831.6 KFM70678.1 - 1.8 8.2 11.7 0.13 11.8 3.7 3.0 2 1 1 3 3 3 0 PHD-finger ubiquitin PF00240.23 KFM70679.1 - 0 996.9 46.3 1.6e-33 114.3 0.3 9.0 9 0 0 9 9 9 9 Ubiquitin family Rad60-SLD PF11976.8 KFM70679.1 - 1.5e-146 476.5 48.2 1.7e-15 56.6 0.4 9.0 9 0 0 9 9 9 9 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFM70679.1 - 1.1e-54 182.8 22.3 0.00038 20.9 0.1 11.3 9 9 0 9 9 9 9 Ubiquitin-like domain TBK1_ULD PF18396.1 KFM70679.1 - 1.2e-33 114.8 16.3 0.075 13.0 0.0 9.2 9 0 0 9 9 9 9 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KFM70679.1 - 9.7e-30 102.8 21.3 0.16 12.3 0.1 9.1 9 0 0 9 9 9 9 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFM70679.1 - 1.3e-29 102.6 15.9 0.25 11.4 0.0 10.2 9 0 0 9 9 9 9 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFM70679.1 - 1.1e-25 90.1 5.3 1.7 9.2 0.0 9.2 1 1 3 9 9 9 9 DUF2407 ubiquitin-like domain DUF2870 PF11069.8 KFM70679.1 - 1.3e-12 47.9 0.0 80 3.7 0.0 9.6 9 0 0 9 9 9 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 KFM70679.1 - 4.7e-11 42.8 15.2 17 5.6 0.0 8.6 9 0 0 9 9 9 0 UDP-glucose:Glycoprotein Glucosyltransferase RBD PF02196.15 KFM70679.1 - 6.4e-11 42.2 0.0 1e+02 3.1 0.0 9.1 9 0 0 9 9 9 0 Raf-like Ras-binding domain DUF969 PF06149.12 KFM70679.1 - 3.6e-09 36.4 0.6 69 2.8 0.0 8.4 9 0 0 9 9 9 0 Protein of unknown function (DUF969) Ubiquitin_4 PF18036.1 KFM70679.1 - 7.6e-08 32.3 58.4 69 3.6 0.0 17.5 18 0 0 18 18 18 0 Ubiquitin-like domain Big_7 PF17957.1 KFM70679.1 - 1.6e-07 32.0 0.0 4.1e+02 1.8 0.0 8.5 9 0 0 9 9 9 0 Bacterial Ig domain ORF11CD3 PF10549.9 KFM70679.1 - 2.5e-07 30.7 0.0 2.5e+02 1.9 0.0 8.8 9 0 0 9 9 9 0 ORF11CD3 domain DUF3861 PF12977.7 KFM70679.1 - 1.4e-06 28.3 11.4 1.3e+02 2.8 0.0 8.9 9 0 0 9 9 9 0 Domain of Unknown Function with PDB structure (DUF3861) TraK PF06586.11 KFM70679.1 - 0.00018 21.3 4.9 2.6e+02 1.1 0.0 8.0 9 0 0 9 9 9 0 TraK protein CorA PF01544.18 KFM70679.1 - 0.026 13.8 10.4 2.3e+02 0.9 0.0 7.8 9 0 0 9 9 9 0 CorA-like Mg2+ transporter protein FlgD_ig PF13860.6 KFM70679.1 - 0.034 14.0 22.3 1.6e+02 2.3 0.1 8.9 9 0 0 9 9 9 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 KFM70679.1 - 0.052 14.0 16.7 1.8e+02 2.7 0.4 8.1 1 1 1 2 2 1 0 Phage tail sheath protein beta-sandwich domain ProRS-C_2 PF09181.10 KFM70679.1 - 0.14 12.3 16.5 3.4e+02 1.5 0.0 8.3 9 0 0 9 9 9 0 Prolyl-tRNA synthetase, C-terminal Spidroin_N PF16763.5 KFM70680.1 - 1.3e-05 25.2 0.5 2.1e-05 24.6 0.5 1.3 1 0 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term DDE_3 PF13358.6 KFM70681.1 - 7.8e-16 58.1 0.1 7.7e-15 54.9 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70681.1 - 8.2e-16 58.0 6.5 1.5e-15 57.2 6.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM70681.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.7 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70681.1 - 0.003 17.3 0.2 0.12 12.2 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70681.1 - 0.018 15.2 0.1 0.065 13.4 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM70681.1 - 0.035 14.1 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Fam20C PF06702.12 KFM70684.1 - 5.7e-95 317.3 0.0 1e-94 316.5 0.0 1.3 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 KFM70684.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 FAM198 protein Mab-21 PF03281.14 KFM70685.1 - 2e-15 56.9 0.1 2.3e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 Mab-21 protein HECW1_helix PF18436.1 KFM70685.1 - 0.0062 16.6 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 Mab-21 PF03281.14 KFM70686.1 - 1e-10 41.4 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein IRF PF00605.17 KFM70687.1 - 6.8e-06 26.3 0.1 1.2e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor RNA_pol_Rpc4 PF05132.14 KFM70688.1 - 2.4e-14 54.0 7.6 3.4e-13 50.3 0.5 3.2 2 1 0 2 2 2 1 RNA polymerase III RPC4 SNF PF00209.18 KFM70690.1 - 1.8e-15 56.7 1.5 2.1e-15 56.5 1.5 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFM70692.1 - 6.9e-45 153.7 7.2 7.6e-45 153.6 7.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RP1-2 PF12042.8 KFM70693.1 - 3e-109 362.3 457.6 1.5e-11 44.4 7.8 28.7 13 6 15 28 28 28 26 Tubuliform egg casing silk strands structural domain Spidroin_N PF16763.5 KFM70693.1 - 6.7e-31 106.9 2.3 6.7e-31 106.9 2.3 11.9 12 1 1 13 13 13 1 Major ampullate spidroin 1, spider silk protein 1, N-term GST_C PF00043.25 KFM70693.1 - 0.009 16.2 3.7 4.3 7.6 0.3 3.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain DUF1128 PF06569.11 KFM70693.1 - 0.0093 15.9 0.0 1.4e+02 2.6 0.0 5.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1128) DUF3562 PF12085.8 KFM70693.1 - 0.035 13.7 0.1 5 6.8 0.0 3.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) HTH_Tnp_Tc3_2 PF01498.18 KFM70694.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70694.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70694.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70694.1 - 0.0023 17.7 0.6 0.0068 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70694.1 - 1.8 9.3 15.7 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain rve PF00665.26 KFM70695.1 - 9.3e-05 22.6 0.0 0.00012 22.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.18 KFM70696.1 - 8.7e-11 41.9 0.8 8.7e-11 41.9 0.8 2.3 3 0 0 3 3 3 1 Transposase HTH_23 PF13384.6 KFM70696.1 - 5.4e-07 29.2 0.8 1.4e-05 24.7 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 KFM70696.1 - 3.4e-05 23.5 0.2 0.039 13.7 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM70696.1 - 0.00032 20.2 0.1 0.0008 18.9 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_7 PF02796.15 KFM70696.1 - 0.0029 17.7 0.5 0.36 10.9 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM70696.1 - 0.0042 17.2 2.0 0.014 15.5 0.1 2.9 4 0 0 4 4 4 1 Helix-turn-helix domain SpoIIID PF12116.8 KFM70696.1 - 0.0089 16.1 0.5 0.9 9.7 0.3 2.4 1 1 1 2 2 2 1 Stage III sporulation protein D PAX PF00292.18 KFM70696.1 - 0.014 15.3 0.3 0.031 14.2 0.2 1.8 1 1 0 1 1 1 0 'Paired box' domain HTH_32 PF13565.6 KFM70696.1 - 0.031 14.9 1.2 0.067 13.8 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_DeoR PF08220.12 KFM70696.1 - 0.077 12.8 0.1 9.2 6.1 0.0 2.4 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Sigma70_ECF PF07638.11 KFM70696.1 - 0.14 12.0 0.3 0.47 10.3 0.1 2.0 2 1 0 2 2 2 0 ECF sigma factor HTH_Tnp_Tc3_1 PF11427.8 KFM70696.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.0 3 2 1 4 4 4 0 Tc3 transposase ABC_tran PF00005.27 KFM70698.1 - 3.5e-31 108.5 0.0 5.8e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM70698.1 - 1.4e-07 31.6 0.0 0.01 15.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM70698.1 - 1e-06 28.3 0.0 3.9e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFM70698.1 - 1e-05 25.5 0.6 1.9e-05 24.7 0.6 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KFM70698.1 - 0.0015 18.2 0.4 0.0043 16.8 0.4 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFM70698.1 - 0.0052 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KFM70698.1 - 0.0056 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KFM70698.1 - 0.0061 17.1 0.2 0.013 16.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM70698.1 - 0.0071 16.6 0.0 0.051 13.8 0.1 2.1 1 1 1 2 2 2 1 AAA domain CHAD PF05235.14 KFM70698.1 - 0.011 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 CHAD domain SbcCD_C PF13558.6 KFM70698.1 - 0.012 15.8 0.0 0.11 12.8 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KFM70698.1 - 0.014 15.8 0.1 0.03 14.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KFM70698.1 - 0.034 13.9 0.2 0.061 13.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 KFM70698.1 - 0.045 12.6 0.1 0.071 11.9 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 KFM70698.1 - 0.051 14.1 0.0 0.097 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFM70698.1 - 0.055 13.2 0.0 0.74 9.5 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain ABC2_membrane PF01061.24 KFM70699.1 - 7.5e-42 143.1 27.3 1e-41 142.7 27.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KFM70699.1 - 0.0019 17.4 26.9 0.0019 17.4 26.9 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF5310 PF17237.2 KFM70699.1 - 0.098 12.5 0.9 0.098 12.5 0.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5310) DUF1440 PF07274.12 KFM70699.1 - 0.47 10.8 5.8 4.9 7.5 4.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1440) DUF2070 PF09843.9 KFM70699.1 - 0.8 7.9 18.4 1 7.6 18.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4229 PF14012.6 KFM70699.1 - 3.1 8.0 7.2 4.2 7.5 4.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Ig_3 PF13927.6 KFM70700.1 - 4.1e-34 117.0 0.7 1.8e-10 41.3 0.1 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM70700.1 - 8.2e-33 112.3 0.0 2.7e-10 40.2 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFM70700.1 - 2.1e-26 91.9 0.2 3.8e-09 36.6 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM70700.1 - 9.3e-22 77.3 0.8 1.4e-08 34.8 0.1 4.5 4 1 0 4 4 4 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM70700.1 - 4.8e-19 68.5 0.7 4.1e-07 30.2 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain fn3 PF00041.21 KFM70700.1 - 1.1e-08 35.3 0.0 3.4e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Ig_6 PF18452.1 KFM70700.1 - 1.1e-07 31.3 0.0 0.0091 15.5 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFM70700.1 - 0.0007 19.6 0.2 0.06 13.4 0.0 3.7 3 2 1 4 4 4 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM70700.1 - 0.09 12.8 0.1 7.3 6.7 0.0 3.6 3 2 0 3 3 3 0 C17orf99 Ig domain C2-set PF05790.15 KFM70700.1 - 0.097 12.9 0.2 31 4.8 0.0 3.9 4 0 0 4 4 4 0 Immunoglobulin C2-set domain DUF2451 PF10474.9 KFM70701.1 - 5.7e-79 265.2 0.8 7.2e-79 264.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF1329 PF07044.11 KFM70701.1 - 0.008 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) Med30 PF11315.8 KFM70701.1 - 0.043 14.0 0.1 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 Mediator complex subunit 30 Vps54_N PF10475.9 KFM70702.1 - 3e-14 53.0 0.9 3e-14 53.0 0.9 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Vps54_N PF10475.9 KFM70703.1 - 1.7e-09 37.4 0.1 1.8e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Vps54_N PF10475.9 KFM70704.1 - 3.1e-35 121.9 4.1 3.7e-35 121.6 4.1 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex HTH_Tnp_Tc3_2 PF01498.18 KFM70705.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70705.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ricin_B_lectin PF00652.22 KFM70706.1 - 1.5e-31 109.3 1.5 2.2e-31 108.8 1.5 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KFM70706.1 - 3.8e-07 30.7 0.2 0.0008 20.1 0.4 2.5 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_transf_7C PF02709.14 KFM70706.1 - 3.3e-05 23.4 0.4 6.5e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DSPc PF00782.20 KFM70707.1 - 7.2e-32 110.0 0.0 9.2e-32 109.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM70707.1 - 0.005 16.4 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase AAA_30 PF13604.6 KFM70707.1 - 0.087 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF5641 PF18701.1 KFM70709.1 - 1.1e-22 79.9 0.3 1.8e-22 79.3 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5641) HTH_Tnp_Tc3_2 PF01498.18 KFM70710.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70710.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SPA PF08616.10 KFM70711.1 - 4.1e-10 39.6 0.1 1e-09 38.4 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KFM70711.1 - 4.2e-06 25.7 0.2 0.0013 17.5 0.1 2.1 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 KFM70711.1 - 0.00018 21.2 0.1 0.00051 19.7 0.1 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DDE_3 PF13358.6 KFM70712.1 - 0.00084 19.1 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Oscp1 PF10188.9 KFM70713.1 - 3.7e-62 209.5 8.4 4e-62 209.4 7.2 1.6 2 0 0 2 2 2 1 Organic solute transport protein 1 DUF3016 PF11454.8 KFM70713.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) DDE_3 PF13358.6 KFM70714.1 - 6.6e-13 48.6 0.0 7.5e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_92 PF01697.27 KFM70714.1 - 0.025 14.3 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 92 SAM_1 PF00536.30 KFM70716.1 - 5.3e-07 30.0 0.3 1.9e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM70716.1 - 2.1e-06 27.8 0.0 8.6e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) FYTT PF07078.11 KFM70716.1 - 0.065 12.6 0.2 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Forty-two-three protein BTB PF00651.31 KFM70719.1 - 1.1e-36 125.4 0.7 1.6e-25 89.5 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain SID-1_RNA_chan PF13965.6 KFM70720.1 - 0.037 12.4 0.3 0.044 12.2 0.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 KFM70720.1 - 0.15 11.3 0.3 0.21 10.8 0.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PRCC PF10253.9 KFM70720.1 - 0.18 12.6 9.0 0.23 12.2 9.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CPSF100_C PF13299.6 KFM70720.1 - 2.9 8.1 7.6 4.3 7.5 7.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_alkylation PF08713.11 KFM70721.1 - 0.0092 15.7 0.0 0.0098 15.6 0.0 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme DDE_Tnp_4 PF13359.6 KFM70722.1 - 7.3e-27 94.0 0.0 9.3e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM70722.1 - 2.2e-06 27.5 0.0 2.8e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein zf-H2C2_2 PF13465.6 KFM70723.1 - 8.3e-43 143.0 38.9 1.5e-08 34.7 0.5 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM70723.1 - 7.1e-35 117.5 44.6 2.1e-07 31.0 1.5 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70723.1 - 3.4e-25 86.5 40.1 0.00059 20.5 0.9 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFM70723.1 - 1.3e-20 73.1 41.3 0.00066 20.0 2.4 6.4 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM70723.1 - 4.1e-13 49.2 30.8 0.02 15.2 0.6 6.5 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM70723.1 - 3e-09 36.5 18.6 0.12 12.4 0.1 6.7 6 1 0 6 6 6 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFM70723.1 - 3.4e-09 36.5 41.7 0.037 14.0 0.4 7.5 6 2 1 7 7 7 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM70723.1 - 8.9e-09 35.0 27.7 0.00054 19.6 0.4 5.9 6 0 0 6 6 5 4 C2H2-type zinc-finger domain zf_UBZ PF18439.1 KFM70723.1 - 3e-06 26.7 23.7 0.23 11.1 0.2 6.2 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger zf-Sec23_Sec24 PF04810.15 KFM70723.1 - 9.4e-06 25.6 21.8 0.057 13.5 0.3 6.1 5 1 1 6 6 6 1 Sec23/Sec24 zinc finger DUF2256 PF10013.9 KFM70723.1 - 1.6e-05 24.9 11.2 9.7 6.4 0.0 6.1 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM70723.1 - 1.9e-05 24.5 16.1 0.047 13.7 1.0 4.1 2 1 3 5 5 5 4 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM70723.1 - 4.3e-05 23.6 0.2 0.019 15.1 0.0 2.7 1 1 0 2 2 2 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif BolA PF01722.18 KFM70723.1 - 9.1e-05 22.7 4.3 2.1 8.7 0.1 4.1 2 2 2 4 4 4 1 BolA-like protein FYVE PF01363.21 KFM70723.1 - 0.00017 21.7 25.4 0.39 10.9 2.2 4.5 1 1 3 4 4 4 1 FYVE zinc finger zf-MYST PF17772.1 KFM70723.1 - 0.00018 21.0 23.1 2.7 7.7 0.1 6.0 3 2 3 6 6 6 1 MYST family zinc finger domain zf-DBF PF07535.12 KFM70723.1 - 0.00035 20.6 23.5 4.8 7.4 0.1 6.3 6 0 0 6 6 6 0 DBF zinc finger Rep_fac-A_C PF08646.10 KFM70723.1 - 0.0038 17.0 16.2 0.069 12.9 2.1 4.6 1 1 3 4 4 4 1 Replication factor-A C terminal domain zinc_ribbon_15 PF17032.5 KFM70723.1 - 0.0068 17.1 17.8 0.67 10.7 0.4 3.1 2 1 1 3 3 3 2 zinc-ribbon family C5HCH PF17982.1 KFM70723.1 - 0.013 15.7 20.9 4 7.7 2.7 5.9 4 2 2 6 6 6 0 NSD Cys-His rich domain Zn-ribbon_8 PF09723.10 KFM70723.1 - 0.016 15.3 16.3 3.8 7.7 2.1 4.5 2 2 1 3 3 3 0 Zinc ribbon domain GAGA PF09237.11 KFM70723.1 - 0.031 14.1 9.8 0.1 12.4 0.1 4.0 2 2 3 5 5 5 0 GAGA factor XPA_N PF01286.18 KFM70723.1 - 0.05 13.6 16.5 41 4.3 0.1 6.1 6 0 0 6 6 6 0 XPA protein N-terminal DZR PF12773.7 KFM70723.1 - 0.051 13.6 14.4 1.1e+02 2.9 10.1 3.8 1 1 1 2 2 2 0 Double zinc ribbon zf-BED PF02892.15 KFM70723.1 - 0.061 13.4 42.3 0.17 11.9 1.8 6.1 1 1 5 6 6 6 0 BED zinc finger zinc-ribbons_6 PF07191.12 KFM70723.1 - 0.064 13.2 19.2 21 5.2 0.1 4.8 1 1 2 3 3 3 0 zinc-ribbons UBZ_FAAP20 PF15750.5 KFM70723.1 - 0.084 12.8 11.0 14 5.7 0.0 5.6 6 0 0 6 6 6 0 Ubiquitin-binding zinc-finger Mga PF05043.13 KFM70723.1 - 0.087 13.4 0.4 10 6.8 0.0 2.7 2 1 1 3 3 2 0 Mga helix-turn-helix domain zf-RRPl_C4 PF17026.5 KFM70723.1 - 0.098 12.8 20.3 1.4 9.1 3.5 3.4 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF3338 PF11819.8 KFM70723.1 - 0.13 12.2 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) zf-C2H2_11 PF16622.5 KFM70723.1 - 0.17 11.6 0.2 0.17 11.6 0.2 5.3 6 0 0 6 6 5 0 zinc-finger C2H2-type TRAF6_Z2 PF18048.1 KFM70723.1 - 0.18 11.9 0.4 0.18 11.9 0.4 5.0 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_9 PF16293.5 KFM70723.1 - 0.31 10.9 21.6 8.2 6.4 0.1 5.5 3 2 3 6 6 6 0 C2H2 type zinc-finger (1 copy) Prok-RING_2 PF14445.6 KFM70723.1 - 0.44 10.8 11.5 15 5.9 0.1 5.3 5 1 1 6 6 6 0 Prokaryotic RING finger family 2 zf-Dof PF02701.15 KFM70723.1 - 0.47 10.6 11.4 37 4.6 0.0 4.9 1 1 4 5 5 5 0 Dof domain, zinc finger zf-C2H2_3rep PF18868.1 KFM70723.1 - 0.61 10.8 20.2 46 4.7 0.3 5.2 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-trcl PF13451.6 KFM70723.1 - 1 9.3 18.3 26 4.8 0.2 5.8 6 0 0 6 6 6 0 Probable zinc-ribbon domain zf-CCHC_2 PF13696.6 KFM70723.1 - 1.1 9.2 33.0 0.55 10.1 0.5 6.2 6 0 0 6 6 6 0 Zinc knuckle zf-RING_UBOX PF13445.6 KFM70723.1 - 1.3 9.1 15.7 36 4.5 0.1 5.7 6 0 0 6 6 6 0 RING-type zinc-finger C1_4 PF07975.12 KFM70723.1 - 2.3 8.5 24.5 0.73 10.1 4.0 4.2 1 1 4 5 5 4 0 TFIIH C1-like domain TerY_C PF15616.6 KFM70723.1 - 2.8 8.1 12.5 18 5.5 1.3 3.7 1 1 3 4 4 4 0 TerY-C metal binding domain zf-RRN7 PF11781.8 KFM70723.1 - 5.4 6.8 16.6 40 4.0 0.1 5.8 6 0 0 6 6 6 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-CCHC_4 PF14392.6 KFM70725.1 - 0.00063 19.4 7.0 0.1 12.3 1.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFM70725.1 - 4.1 7.3 15.4 1.8 8.5 1.6 3.6 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFM70726.1 - 0.0029 17.3 7.2 0.12 12.2 1.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFM70726.1 - 3.7 7.5 13.0 2 8.3 1.6 3.5 3 0 0 3 3 3 0 Zinc knuckle HTH_Tnp_Tc3_2 PF01498.18 KFM70727.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70727.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70727.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70727.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70727.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ig_3 PF13927.6 KFM70728.1 - 0.0028 18.2 0.0 0.0046 17.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM70728.1 - 0.0078 16.5 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM70728.1 - 0.01 15.9 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFM70728.1 - 0.032 14.3 0.1 0.23 11.5 0.1 2.0 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DDE_Tnp_1_7 PF13843.6 KFM70729.1 - 2.3e-56 191.6 0.1 2.9e-56 191.3 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM70729.1 - 3.8 8.4 8.8 5.3 7.9 5.9 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon HTH_Tnp_Tc3_2 PF01498.18 KFM70730.1 - 4.9e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70730.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70730.1 - 2e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70730.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70730.1 - 2.4 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM70731.1 - 1.4e-07 31.1 0.0 1.5e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 RNA_pol_I_A49 PF06870.12 KFM70732.1 - 2.8e-32 112.0 0.1 3.7e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor HTH_Tnp_Tc5 PF03221.16 KFM70733.1 - 6.3e-12 45.3 0.2 9.4e-12 44.8 0.0 1.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF3748 PF12566.8 KFM70733.1 - 0.064 13.2 0.1 1.1 9.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3748) Zip PF02535.22 KFM70734.1 - 1.6e-11 44.0 0.3 1.8e-11 43.9 0.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter T2SSF PF00482.23 KFM70734.1 - 0.02 14.9 0.0 0.022 14.7 0.0 1.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Adeno_PX PF05829.12 KFM70734.1 - 0.83 9.6 6.5 1.6 8.6 6.5 1.5 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) PetM PF08041.11 KFM70734.1 - 1.4 8.5 4.5 9.8 5.9 0.3 2.1 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 PDZ PF00595.24 KFM70736.1 - 1.1e-08 35.3 0.1 2.6e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM70736.1 - 0.038 14.3 0.2 0.58 10.5 0.0 2.7 4 0 0 4 4 4 0 PDZ domain TPP_enzyme_N PF02776.18 KFM70737.1 - 2.2e-46 157.6 0.3 4.1e-46 156.7 0.3 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFM70737.1 - 1.5e-26 93.0 0.0 8.8e-26 90.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFM70737.1 - 1.9e-17 63.3 0.0 1.3e-16 60.5 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain ArfGap PF01412.18 KFM70738.1 - 8.8e-05 22.6 0.8 0.00014 22.0 0.1 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DIL PF01843.19 KFM70739.1 - 3.3e-29 101.2 2.2 3.3e-29 101.2 2.2 2.1 2 0 0 2 2 2 1 DIL domain Ac76 PF05814.11 KFM70739.1 - 0.14 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Orf76 (Ac76) Myosin_head PF00063.21 KFM70740.1 - 2.9e-97 326.5 3.6 2.9e-97 326.5 3.6 3.0 2 1 1 3 3 3 2 Myosin head (motor domain) IQ PF00612.27 KFM70740.1 - 4.1e-19 66.5 41.4 7.8e-05 22.1 0.4 6.6 6 0 0 6 6 6 6 IQ calmodulin-binding motif TBPIP PF07106.13 KFM70740.1 - 0.02 14.8 0.1 0.11 12.5 0.1 2.3 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain GIT_CC PF16559.5 KFM70740.1 - 5.8 6.9 38.4 0.025 14.5 4.5 6.8 6 1 1 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor Myosin_head PF00063.21 KFM70741.1 - 5.7e-151 504.0 1.8 6.5e-151 503.8 1.8 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KFM70741.1 - 1.6e-08 34.2 1.1 3.5e-08 33.1 0.9 1.7 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFM70741.1 - 0.0044 17.3 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain 4_1_CTD PF05902.13 KFM70741.1 - 0.017 15.2 0.2 0.035 14.2 0.2 1.5 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) AAA_16 PF13191.6 KFM70741.1 - 0.021 15.2 0.2 0.044 14.2 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.7 KFM70741.1 - 0.026 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain T2SSE PF00437.20 KFM70741.1 - 0.062 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein QIL1 PF15884.5 KFM70742.1 - 2.1e-08 34.6 0.1 3.8e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 MICOS complex subunit MIC13, QIL1 RPN7 PF10602.9 KFM70742.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DUF1572 PF07609.11 KFM70742.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) RVT_1 PF00078.27 KFM70747.1 - 0.091 12.3 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KFM70749.1 - 3.9e-05 23.5 0.7 6.5e-05 22.8 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle PNMA PF14893.6 KFM70749.1 - 0.0013 18.2 0.2 0.0054 16.2 0.0 1.9 2 0 0 2 2 2 1 PNMA SKA2 PF16740.5 KFM70749.1 - 0.02 14.7 2.1 3.4 7.5 0.1 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Retrotrans_gag PF03732.17 KFM70749.1 - 0.091 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 KFM70749.1 - 0.23 11.2 0.7 0.42 10.4 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle SlyX PF04102.12 KFM70749.1 - 0.34 11.5 2.4 1.2 9.8 0.7 2.5 2 0 0 2 2 2 0 SlyX Fib_alpha PF08702.10 KFM70749.1 - 0.43 10.8 4.4 1 9.5 0.3 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Cep57_MT_bd PF06657.13 KFM70749.1 - 3.1 8.3 4.6 20 5.7 0.0 2.7 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 KFM70749.1 - 6.9 5.9 7.4 15 4.8 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 KFM70750.1 - 1.8e-14 53.8 0.1 3.2e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Neur_chan_LBD PF02931.23 KFM70751.1 - 6.2e-07 29.1 0.3 6.3e-07 29.1 0.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain GST_C_3 PF14497.6 KFM70752.1 - 1.2e-15 57.5 0.1 1.9e-15 56.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFM70752.1 - 2.7e-13 50.1 0.0 6.3e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFM70752.1 - 4.4e-10 39.6 0.1 7.1e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM70752.1 - 4.7e-07 29.7 0.2 8.2e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM70752.1 - 0.0014 19.0 0.1 0.0025 18.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KFM70752.1 - 0.01 15.6 0.6 0.059 13.2 0.6 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ADAM_CR_2 PF17771.1 KFM70753.1 - 7.2e-20 71.3 9.4 7.2e-20 71.3 9.4 1.7 2 1 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin PF01421.19 KFM70753.1 - 1.1e-05 25.4 0.2 1.8e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease UPF0506 PF11703.8 KFM70753.1 - 0.033 14.6 8.0 0.2 12.1 6.0 2.5 2 0 0 2 2 2 0 UPF0506 ADAM_spacer1 PF05986.14 KFM70755.1 - 0.012 15.7 0.0 0.012 15.7 0.0 1.0 1 0 0 1 1 1 0 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFM70756.1 - 2e-23 82.3 66.0 3.7e-06 27.1 7.0 6.5 6 0 0 6 6 6 5 Thrombospondin type 1 domain GON PF08685.11 KFM70758.1 - 3.1e-59 200.2 1.0 5e-59 199.6 1.0 1.3 1 0 0 1 1 1 1 GON domain Ion_trans_2 PF07885.16 KFM70759.1 - 1.4e-06 28.1 6.6 4.7e-05 23.3 3.2 2.3 2 0 0 2 2 2 2 Ion channel MFS_Mycoplasma PF07672.13 KFM70759.1 - 0.0055 16.0 0.6 0.0056 16.0 0.6 1.0 1 0 0 1 1 1 1 Mycoplasma MFS transporter HTH_Tnp_Tc3_2 PF01498.18 KFM70760.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70760.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_34 PF11312.8 KFM70763.1 - 0.0068 15.7 0.1 0.0083 15.4 0.1 1.3 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase DDE_3 PF13358.6 KFM70764.1 - 0.00061 19.6 0.0 0.00086 19.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70765.1 - 2.4e-16 59.7 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70765.1 - 9.8e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 KFM70767.1 - 2.5e-51 174.6 0.0 3.1e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM70767.1 - 1.9e-22 79.8 0.1 2.4e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM70767.1 - 0.00032 20.7 0.0 0.00066 19.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFM70767.1 - 0.00038 20.1 0.1 0.0007 19.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KFM70767.1 - 0.00046 19.6 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM70767.1 - 0.002 17.5 0.1 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFM70767.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFM70767.1 - 0.17 10.8 0.1 0.31 9.9 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain THAP PF05485.12 KFM70769.1 - 0.018 16.0 0.3 0.026 15.4 0.3 1.3 1 0 0 1 1 1 0 THAP domain DUF4364 PF14277.6 KFM70769.1 - 0.047 13.4 1.2 0.076 12.8 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) COPR5 PF15340.6 KFM70769.1 - 0.1 13.2 0.1 0.13 12.9 0.1 1.2 1 0 0 1 1 1 0 Cooperator of PRMT5 family SCP2 PF02036.17 KFM70770.1 - 9e-09 35.8 0.2 1.3e-08 35.3 0.2 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Band_7 PF01145.25 KFM70771.1 - 3.3e-14 53.3 0.0 5.7e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family ORF45 PF17620.2 KFM70773.1 - 0.00032 20.9 0.4 0.00043 20.5 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function SCAN PF02023.17 KFM70773.1 - 0.00066 19.5 0.7 0.0019 18.0 0.4 2.0 2 0 0 2 2 2 1 SCAN domain AMP-binding PF00501.28 KFM70774.1 - 5.4e-21 74.7 0.0 7.4e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KFM70775.1 - 1.9e-61 208.0 0.0 2.2e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM70775.1 - 7.1e-07 30.1 0.0 1.4e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VKG_Carbox PF05090.14 KFM70776.1 - 2.2e-66 224.5 4.2 2.5e-66 224.3 4.2 1.0 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase VKG_Carbox PF05090.14 KFM70777.1 - 7.3e-37 127.2 2.0 8.4e-37 127.0 2.0 1.0 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase Cupin_2 PF07883.11 KFM70778.1 - 0.0042 16.8 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain MMS1_N PF10433.9 KFM70779.1 - 0.063 11.9 0.0 0.063 11.9 0.0 1.0 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4371 PF14291.6 KFM70780.1 - 2.5e-06 27.3 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KFM70780.1 - 7.7e-06 25.8 0.5 1.2e-05 25.3 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PHD_2 PF13831.6 KFM70781.1 - 0.066 12.8 0.1 0.088 12.4 0.1 1.2 1 0 0 1 1 1 0 PHD-finger Folliculin PF11704.8 KFM70782.1 - 1.6e-44 152.0 0.0 2.3e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Sterile PF03015.19 KFM70782.1 - 0.14 12.4 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein Folliculin_C PF16692.5 KFM70783.1 - 1.1e-57 195.3 0.1 1.5e-57 194.9 0.1 1.1 1 0 0 1 1 1 1 Folliculin C-terminal domain Folliculin PF11704.8 KFM70783.1 - 2e-09 37.6 0.0 3.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DDE_3 PF13358.6 KFM70784.1 - 0.024 14.4 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease LCAT PF02450.15 KFM70785.1 - 1.3e-78 264.9 1.2 2.4e-69 234.4 0.3 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 KFM70785.1 - 0.00069 19.3 0.0 0.0025 17.5 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM70785.1 - 0.0047 16.2 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFM70785.1 - 0.082 12.6 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_M20 PF01546.28 KFM70786.1 - 0.00041 20.1 0.2 0.00058 19.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PDZ PF00595.24 KFM70788.1 - 2.3e-10 40.7 0.0 6e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM70788.1 - 8.2e-09 35.2 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM70788.1 - 0.00099 19.4 0.0 0.0033 17.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain DUF4371 PF14291.6 KFM70789.1 - 0.0091 15.7 0.9 0.0099 15.5 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) RNase_H PF00075.24 KFM70790.1 - 1.4e-15 57.7 0.0 1.9e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM70790.1 - 0.0078 16.0 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like Arm_2 PF04826.13 KFM70791.1 - 4.6e-13 49.2 1.3 5.2e-13 49.0 1.3 1.0 1 0 0 1 1 1 1 Armadillo-like PTS_EIIA_2 PF00359.22 KFM70791.1 - 0.12 12.3 0.3 0.3 11.0 0.1 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF1899 PF08953.11 KFM70792.1 - 0.098 12.5 0.4 0.43 10.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) HTH_Tnp_Tc3_2 PF01498.18 KFM70793.1 - 4.8e-16 58.8 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70793.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70793.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70793.1 - 0.0025 17.5 0.6 0.0076 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70793.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Insulin PF00049.18 KFM70794.1 - 1.1e-13 52.0 1.3 2.6e-13 50.8 1.3 1.6 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFM70794.1 - 6.6e-06 26.0 2.2 0.059 13.4 0.0 2.3 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type AAA PF00004.29 KFM70795.1 - 9e-09 35.8 0.2 5.9e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 KFM70795.1 - 0.00067 19.2 0.2 0.0021 17.7 0.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif RuvB_N PF05496.12 KFM70795.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KFM70795.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase HTH_Tnp_Tc3_2 PF01498.18 KFM70796.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70796.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70796.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70796.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70796.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM70797.1 - 2.1e-16 59.9 2.2 4.8e-16 58.8 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70797.1 - 9.2e-14 51.4 0.0 1.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3730 PF12530.8 KFM70797.1 - 0.11 12.1 0.2 6.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) Prokineticin PF06607.11 KFM70798.1 - 1.8e-06 28.2 7.5 2.7e-06 27.6 7.5 1.2 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM70798.1 - 0.11 13.1 8.9 0.24 12.0 8.9 1.6 1 0 0 1 1 1 0 MIT-like atracotoxin family Prokineticin PF06607.11 KFM70799.1 - 1.5e-05 25.2 7.6 2.3e-05 24.6 7.6 1.2 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM70799.1 - 0.044 14.4 8.8 0.1 13.2 8.8 1.6 1 0 0 1 1 1 0 MIT-like atracotoxin family Peptidase_A17 PF05380.13 KFM70800.1 - 8.5e-05 22.6 0.1 9.3e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Pao retrotransposon peptidase SIX1_SD PF16878.5 KFM70801.1 - 2.8e-33 114.7 0.2 3.2e-33 114.5 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain GAIN PF16489.5 KFM70803.1 - 0.0015 18.0 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain DDE_3 PF13358.6 KFM70804.1 - 2.4e-16 59.8 0.1 3.1e-15 56.2 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70804.1 - 1.5e-10 41.2 1.0 2.8e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Transposase_1 PF01359.18 KFM70806.1 - 6.7e-14 51.5 0.4 1.4e-13 50.4 0.1 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM70806.1 - 7.4e-09 35.5 0.1 1.3e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_48 PF17906.1 KFM70806.1 - 1.2e-06 28.5 0.0 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_29 PF13551.6 KFM70806.1 - 6.4e-06 26.1 1.1 0.013 15.5 0.0 3.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_32 PF13565.6 KFM70806.1 - 0.00021 21.8 3.8 0.00044 20.8 0.3 3.1 2 1 1 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70806.1 - 0.00024 21.2 2.0 0.0064 16.6 0.1 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70806.1 - 0.0076 16.0 5.8 0.021 14.6 0.0 3.4 4 0 0 4 4 4 1 Homeodomain-like domain Ninjurin PF04923.12 KFM70808.1 - 1.5e-35 121.2 11.3 1.9e-35 120.9 11.3 1.1 1 0 0 1 1 1 1 Ninjurin Tetraspanin PF00335.20 KFM70808.1 - 0.11 12.2 0.9 0.14 11.9 0.9 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF4231 PF14015.6 KFM70808.1 - 0.48 10.9 4.0 0.48 10.9 2.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF5383 PF17355.2 KFM70808.1 - 0.7 10.3 3.8 7.1 7.0 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5383) Ninjurin PF04923.12 KFM70809.1 - 1.3e-35 121.4 8.6 1.7e-35 121.1 8.6 1.1 1 0 0 1 1 1 1 Ninjurin HTH_Tnp_Tc3_2 PF01498.18 KFM70810.1 - 1.9e-16 60.0 2.5 4.2e-16 58.9 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70810.1 - 9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DCB PF16213.5 KFM70813.1 - 4.1e-10 39.6 0.3 5.4e-10 39.2 0.3 1.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KFM70814.1 - 5.9e-83 279.4 0.3 8.3e-83 278.9 0.3 1.2 1 0 0 1 1 1 1 C-terminal region of Mon2 protein Sec7_N PF12783.7 KFM70814.1 - 1.6e-22 80.1 1.5 1.6e-22 80.1 1.5 2.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KFM70814.1 - 7.6e-18 64.1 0.9 5.2e-16 58.3 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) HEAT PF02985.22 KFM70814.1 - 0.43 11.0 2.0 1.6e+02 3.0 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat Mon2_C PF16206.5 KFM70815.1 - 3.3e-50 171.1 0.6 3.9e-50 170.9 0.6 1.0 1 0 0 1 1 1 1 C-terminal region of Mon2 protein RmuC PF02646.16 KFM70815.1 - 0.069 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 RmuC family Mon2_C PF16206.5 KFM70816.1 - 2.8e-33 115.1 0.0 3e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 C-terminal region of Mon2 protein Mon2_C PF16206.5 KFM70817.1 - 6.5e-27 94.0 0.3 7.1e-27 93.9 0.3 1.0 1 0 0 1 1 1 1 C-terminal region of Mon2 protein RAMP PF04901.13 KFM70817.1 - 0.019 15.0 0.4 0.029 14.4 0.4 1.4 1 1 0 1 1 1 0 Receptor activity modifying family HTH_Tnp_Tc3_2 PF01498.18 KFM70818.1 - 3.6e-14 52.8 2.1 4.2e-14 52.5 1.0 1.7 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 KFM70818.1 - 1.4e-07 31.5 1.1 1.8e-05 24.7 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.18 KFM70818.1 - 4.3e-06 26.6 0.2 8.2e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFM70818.1 - 3.7e-05 23.4 4.1 0.0032 17.2 0.0 3.1 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM70818.1 - 0.0003 20.8 1.4 0.0048 16.9 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KFM70818.1 - 0.00032 21.3 4.7 0.00032 21.3 4.7 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_37 PF13744.6 KFM70818.1 - 0.0015 18.5 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 KFM70818.1 - 0.009 16.1 0.3 0.29 11.2 0.1 2.3 2 0 0 2 2 2 1 Transposase HTH_3 PF01381.22 KFM70818.1 - 0.013 15.5 0.4 0.43 10.7 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.6 KFM70818.1 - 0.015 15.1 3.7 0.023 14.5 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM70818.1 - 0.03 13.7 0.7 1.7 8.1 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 KFM70818.1 - 0.035 14.2 3.8 0.88 9.7 1.8 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_22 PF13309.6 KFM70818.1 - 0.052 13.6 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_Tnp_Tc3_2 PF01498.18 KFM70819.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70819.1 - 8.9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70820.1 - 7.4e-16 58.2 6.5 1.3e-15 57.4 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70820.1 - 8.4e-15 54.8 0.1 3.9e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM70820.1 - 0.00059 20.4 1.4 0.00059 20.4 1.4 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70820.1 - 0.003 17.3 0.2 0.11 12.3 0.0 3.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM70820.1 - 0.065 13.3 2.4 0.082 12.9 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM70821.1 - 4.1e-16 59.0 3.5 5.7e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70821.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70821.1 - 7e-07 28.9 0.2 7e-07 28.9 0.2 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70821.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70821.1 - 0.026 14.6 0.4 0.09 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM70821.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain B2-adapt-app_C PF09066.10 KFM70822.1 - 1.4e-36 124.9 0.6 4.2e-36 123.4 0.3 1.8 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Alpha_adaptinC2 PF02883.20 KFM70822.1 - 1e-06 29.0 1.5 1e-06 29.0 1.5 1.9 2 1 1 3 3 3 1 Adaptin C-terminal domain Adaptin_N PF01602.20 KFM70823.1 - 1.5e-160 535.3 14.9 1.8e-160 534.9 14.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFM70823.1 - 1.3e-65 220.3 12.5 6.9e-63 211.5 1.3 4.0 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM70823.1 - 1.9e-23 82.6 8.4 3.8e-06 27.2 0.0 6.7 2 2 5 8 8 8 6 HEAT repeats HEAT PF02985.22 KFM70823.1 - 2.1e-13 49.3 9.5 0.029 14.6 0.0 8.3 8 0 0 8 8 7 3 HEAT repeat Arm PF00514.23 KFM70823.1 - 8.6e-10 38.3 4.5 0.002 18.1 0.1 6.3 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 KFM70823.1 - 2.2e-06 27.1 5.0 8.3e-06 25.2 0.2 3.1 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 KFM70823.1 - 7.4e-06 25.7 3.4 0.015 14.8 0.1 4.4 2 2 1 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 KFM70823.1 - 7e-05 23.0 7.4 0.54 10.5 0.1 5.0 1 1 3 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KFM70823.1 - 0.00031 21.2 8.5 0.41 11.2 0.1 6.5 6 2 1 7 7 7 1 HEAT-like repeat Sec7_N PF12783.7 KFM70823.1 - 0.0018 18.2 0.7 0.0018 18.2 0.7 3.4 3 1 2 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal API5 PF05918.11 KFM70823.1 - 0.042 12.7 2.6 0.14 10.9 0.1 2.8 2 2 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Epimerase PF01370.21 KFM70823.1 - 0.13 11.7 0.1 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF5578 PF17741.1 KFM70823.1 - 0.25 10.7 6.2 2.1 7.7 0.3 4.0 2 2 1 4 4 4 0 Family of unknown function (DUF5578) RasGEF_N_2 PF14663.6 KFM70823.1 - 0.3 11.5 5.4 31 5.0 0.1 4.8 3 1 2 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RIX1 PF08167.12 KFM70823.1 - 1.4 8.6 9.3 3.2 7.4 0.0 3.6 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis HTH_Tnp_Tc3_2 PF01498.18 KFM70824.1 - 2e-16 60.0 2.2 4.2e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70824.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1758 PF05585.12 KFM70827.1 - 0.00017 21.4 0.0 0.00018 21.3 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Peptidase_A17 PF05380.13 KFM70828.1 - 1e-21 77.6 0.1 1.1e-21 77.5 0.1 1.1 1 0 0 1 1 1 1 Pao retrotransposon peptidase Glyco_hydro_31 PF01055.26 KFM70830.1 - 1.1e-54 186.3 2.1 1.6e-54 185.8 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Fibrinogen_C PF00147.18 KFM70831.1 - 2.5e-62 210.6 9.0 3e-62 210.3 9.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Tektin PF03148.14 KFM70832.1 - 8.1e-05 21.5 4.4 0.00014 20.7 4.4 1.3 1 0 0 1 1 1 1 Tektin family Prominin PF05478.11 KFM70832.1 - 5.5 4.8 8.6 2.5 5.9 4.9 1.8 2 0 0 2 2 2 0 Prominin betaPIX_CC PF16523.5 KFM70832.1 - 8.5 6.3 12.7 1 9.2 4.3 2.6 2 0 0 2 2 2 0 betaPIX coiled coil LcnG-beta PF11632.8 KFM70833.1 - 0.21 11.6 0.2 0.48 10.4 0.2 1.5 1 0 0 1 1 1 0 Lactococcin G-beta MAP7 PF05672.11 KFM70833.1 - 3.5 7.3 45.9 0.41 10.3 2.9 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family HHH_3 PF12836.7 KFM70834.1 - 6.2e-37 125.7 0.0 6.1e-19 68.0 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH PF00633.23 KFM70834.1 - 9.6e-09 34.7 0.0 0.0002 21.1 0.0 4.3 4 0 0 4 4 4 2 Helix-hairpin-helix motif T2SSK PF03934.13 KFM70834.1 - 4.2e-07 29.6 0.1 0.0031 17.0 0.0 2.3 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein K HHH_6 PF14579.6 KFM70834.1 - 1.7e-06 28.2 0.0 0.048 13.9 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KFM70834.1 - 0.0024 18.4 0.1 0.32 11.6 0.0 3.6 4 0 0 4 4 4 1 Helix-hairpin-helix domain PsbU PF06514.11 KFM70834.1 - 0.0089 16.0 0.2 0.92 9.5 0.0 3.3 4 0 0 4 4 4 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_2 PF12826.7 KFM70834.1 - 0.025 14.7 0.0 0.67 10.1 0.0 2.9 3 1 1 4 4 4 0 Helix-hairpin-helix motif CAV_VP3 PF04771.12 KFM70834.1 - 0.16 12.1 0.2 0.39 10.9 0.2 1.6 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein hNIFK_binding PF12196.8 KFM70835.1 - 0.14 11.7 1.3 0.16 11.5 0.2 1.7 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK DUF2129 PF09902.9 KFM70835.1 - 0.2 11.7 0.0 0.28 11.3 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) Toxin_30 PF08117.11 KFM70836.1 - 0.088 13.1 3.6 0.18 12.1 3.6 1.4 1 0 0 1 1 1 0 Ptu family Conotoxin PF02950.17 KFM70836.1 - 0.38 11.8 5.4 1.1 10.3 5.4 1.8 1 1 0 1 1 1 0 Conotoxin Toxin_35 PF10530.9 KFM70837.1 - 0.057 13.4 0.6 0.089 12.8 0.6 1.3 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold Toxin_30 PF08117.11 KFM70837.1 - 3 8.2 9.4 0.29 11.4 3.2 2.1 2 0 0 2 2 2 0 Ptu family Conotoxin PF02950.17 KFM70838.1 - 0.078 14.0 5.7 0.27 12.3 5.7 1.9 1 1 0 1 1 1 0 Conotoxin MIP-T3 PF10243.9 KFM70838.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain RT_RNaseH_2 PF17919.1 KFM70839.1 - 1.3e-30 105.4 0.0 5.6e-30 103.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM70839.1 - 3.4e-29 101.2 0.0 1.6e-28 99.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM70839.1 - 2.6e-28 99.1 0.1 6.5e-28 97.8 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM70839.1 - 2.6e-18 66.3 0.0 4.1e-17 62.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM70839.1 - 2.7e-16 59.4 0.0 8.8e-16 57.8 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Exo_endo_phos_2 PF14529.6 KFM70839.1 - 4.4e-16 58.8 0.0 1.3e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Arc_C PF18162.1 KFM70839.1 - 4.9e-05 23.1 1.7 0.00015 21.5 0.4 2.6 3 0 0 3 3 3 1 Arc C-lobe zf-H2C2 PF09337.10 KFM70839.1 - 0.0018 18.4 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM70839.1 - 0.029 14.6 2.8 0.26 11.6 0.0 3.7 3 0 0 3 3 3 0 Retrotransposon gag protein GIY-YIG PF01541.24 KFM70840.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 GIY-YIG catalytic domain Spectrin PF00435.21 KFM70841.1 - 0.12 12.9 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Spectrin repeat Conotoxin PF02950.17 KFM70841.1 - 0.98 10.5 4.5 2.7 9.1 4.5 1.8 1 1 0 1 1 1 0 Conotoxin Toxin_30 PF08117.11 KFM70841.1 - 1.5 9.2 8.0 0.36 11.1 3.3 2.1 2 0 0 2 2 2 0 Ptu family Jiv90 PF14901.6 KFM70842.1 - 0.6 10.3 3.5 1.2 9.3 3.5 1.5 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone zf-CCHC_3 PF13917.6 KFM70842.1 - 2.4 8.2 11.0 0.18 11.8 5.0 2.2 2 0 0 2 2 2 0 Zinc knuckle Spectrin PF00435.21 KFM70843.1 - 0.025 15.0 0.0 0.035 14.6 0.0 1.1 1 0 0 1 1 1 0 Spectrin repeat Conotoxin PF02950.17 KFM70843.1 - 0.12 13.4 4.0 0.51 11.4 4.0 1.9 1 1 0 1 1 1 0 Conotoxin DDE_3 PF13358.6 KFM70844.1 - 5.3e-27 94.4 0.0 2.1e-12 47.0 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70844.1 - 4.2e-07 30.1 0.4 9.7e-06 25.7 0.6 2.4 2 0 0 2 2 2 1 Transposase Spectrin PF00435.21 KFM70845.1 - 0.051 14.1 0.0 0.07 13.6 0.0 1.2 1 0 0 1 1 1 0 Spectrin repeat Herpeto_peptide PF14409.6 KFM70845.1 - 0.093 13.0 0.3 21 5.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Herpetosiphon Conotoxin PF02950.17 KFM70845.1 - 0.3 12.1 4.0 0.73 10.9 4.0 1.7 1 1 0 1 1 1 0 Conotoxin Alk_phosphatase PF00245.20 KFM70846.1 - 2.4e-75 254.0 0.0 2.7e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Prokineticin PF06607.11 KFM70848.1 - 0.021 15.1 2.5 0.028 14.7 2.5 1.3 1 0 0 1 1 1 0 Prokineticin HTH_Tnp_Tc3_2 PF01498.18 KFM70849.1 - 5.9e-13 48.9 0.6 5.9e-13 48.9 0.6 1.7 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM70849.1 - 0.0016 18.2 0.1 0.0045 16.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM70849.1 - 0.0038 17.8 1.3 0.0061 17.2 1.3 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 KFM70849.1 - 0.0096 16.0 0.0 0.029 14.4 0.0 1.9 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase Lumazine_bd_2 PF12893.7 KFM70849.1 - 0.0099 16.5 0.1 0.012 16.3 0.1 1.1 1 0 0 1 1 1 1 Putative lumazine-binding HTH_Tnp_ISL3 PF13542.6 KFM70849.1 - 0.014 14.8 4.0 0.24 10.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.6 KFM70849.1 - 0.065 13.4 0.3 0.38 10.9 0.2 2.0 2 0 0 2 2 2 0 HTH-like domain HTH_28 PF13518.6 KFM70849.1 - 0.08 13.1 0.1 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain NNMT_PNMT_TEMT PF01234.17 KFM70850.1 - 2e-38 132.0 0.0 2.5e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 KFM70850.1 - 0.00033 20.5 0.0 0.00047 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM70850.1 - 0.002 18.8 0.0 0.018 15.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM70850.1 - 0.034 14.8 0.0 0.82 10.4 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KFM70850.1 - 0.086 12.7 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase CMAS PF02353.20 KFM70850.1 - 0.088 12.1 0.0 1 8.6 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase NNMT_PNMT_TEMT PF01234.17 KFM70851.1 - 6.5e-35 120.5 0.1 6.9e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 KFM70851.1 - 0.0028 18.4 0.0 0.009 16.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM70851.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain GP3 PF03076.14 KFM70851.1 - 0.068 13.2 0.1 0.12 12.4 0.1 1.4 2 0 0 2 2 2 0 Equine arteritis virus GP3 Methyltransf_31 PF13847.6 KFM70851.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KFM70851.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KFM70851.1 - 0.12 13.1 0.0 0.35 11.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MRP-S27 PF10037.9 KFM70852.1 - 2e-80 270.6 2.9 2.2e-80 270.5 2.9 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.6 KFM70852.1 - 1.9e-05 24.8 0.2 4.1e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.6 KFM70852.1 - 0.01 15.9 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 0 Pentatricopeptide repeat domain SIX1_SD PF16878.5 KFM70852.1 - 0.012 16.1 0.6 0.026 15.0 0.6 1.6 1 1 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain PPR_1 PF12854.7 KFM70852.1 - 0.042 13.6 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 PPR repeat HTH_Tnp_Tc3_2 PF01498.18 KFM70853.1 - 2.3e-16 59.8 2.2 4.9e-16 58.7 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70853.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GBP PF02263.19 KFM70854.1 - 4.7e-95 317.8 0.0 8.9e-95 316.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KFM70854.1 - 5.6e-06 26.0 0.4 8.3e-06 25.4 0.4 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 KFM70854.1 - 0.03 14.7 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain zf-C2H2 PF00096.26 KFM70855.1 - 1.7e-06 28.2 0.5 3.3e-06 27.2 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70855.1 - 0.00016 22.2 0.9 0.00033 21.2 0.5 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM70855.1 - 0.00054 19.9 0.6 0.0011 18.9 0.2 1.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM70855.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFM70855.1 - 0.0035 17.6 0.1 0.0061 16.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFM70856.1 - 0.005 17.2 2.0 0.013 16.0 2.0 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM70856.1 - 0.016 16.0 1.8 0.016 16.0 1.8 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM70856.1 - 0.19 12.2 0.3 0.19 12.2 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double domain ELM2 PF01448.24 KFM70857.1 - 9.4e-06 26.3 0.0 0.00031 21.4 0.0 2.5 2 0 0 2 2 2 1 ELM2 domain RVT_1 PF00078.27 KFM70858.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4467 PF14729.6 KFM70858.1 - 0.077 13.4 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) COX7C PF02935.16 KFM70860.1 - 1.2e-18 67.1 0.9 1.4e-18 66.9 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc ERG4_ERG24 PF01222.17 KFM70862.1 - 1.2e-35 123.2 2.9 1.3e-35 123.0 2.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KFM70862.1 - 8.1e-08 32.1 0.2 1.2e-07 31.5 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KFM70862.1 - 1.6e-05 25.2 1.3 4.6e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KFM70862.1 - 0.0016 18.8 0.4 0.0027 18.1 0.4 1.5 1 1 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.11 KFM70862.1 - 0.018 14.5 0.1 0.023 14.2 0.1 1.3 1 1 0 1 1 1 0 NnrU protein LBR_tudor PF09465.10 KFM70863.1 - 2.9e-12 46.2 0.6 5.4e-12 45.3 0.1 1.8 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain ERG4_ERG24 PF01222.17 KFM70863.1 - 5.4e-10 38.6 7.0 6.7e-10 38.3 7.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Tudor_3 PF18115.1 KFM70863.1 - 1.1e-06 28.3 0.0 2.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Tudor_2 PF18104.1 KFM70863.1 - 0.00033 20.3 0.3 0.00033 20.3 0.3 2.4 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain 53-BP1_Tudor PF09038.10 KFM70863.1 - 0.0046 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor TUDOR_5 PF18359.1 KFM70863.1 - 0.0086 15.8 0.1 0.021 14.5 0.1 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 TUDOR PF00567.24 KFM70863.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Tudor domain DUF4537 PF15057.6 KFM70863.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) DDE_3 PF13358.6 KFM70864.1 - 0.026 14.3 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease WH1 PF00568.23 KFM70865.1 - 1.3e-32 112.0 0.1 2.6e-32 111.1 0.1 1.5 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 KFM70865.1 - 1.6e-09 37.2 4.9 1.6e-09 37.2 4.9 1.9 3 0 0 3 3 3 1 VASP tetramerisation domain Ran_BP1 PF00638.18 KFM70865.1 - 6.5e-05 23.2 0.6 0.00013 22.2 0.0 1.7 2 0 0 2 2 2 1 RanBP1 domain HTH_Tnp_Tc3_2 PF01498.18 KFM70867.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70867.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM70868.1 - 5.5e-16 58.6 0.1 5.8e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70868.1 - 7.6e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM70868.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70868.1 - 0.0017 18.1 0.1 0.079 12.8 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM70868.1 - 0.0049 16.9 1.6 0.009 16.0 0.2 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM70868.1 - 0.016 15.3 0.1 0.074 13.2 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 KFM70868.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Fer2 PF00111.27 KFM70869.1 - 8.4e-09 35.3 0.4 1e-08 35.0 0.4 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain WD40 PF00400.32 KFM70871.1 - 3.3e-25 87.8 19.4 5.7e-07 30.1 0.0 6.1 6 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM70871.1 - 3.3e-08 33.7 0.4 1.1 9.6 0.0 5.6 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM70871.1 - 0.0025 17.7 0.0 0.16 11.9 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFM70871.1 - 0.028 13.4 0.0 0.9 8.4 0.0 3.0 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Kelch_6 PF13964.6 KFM70871.1 - 0.039 14.3 0.6 12 6.4 0.1 3.0 2 0 0 2 2 2 0 Kelch motif PD40 PF07676.12 KFM70871.1 - 0.12 12.4 0.5 69 3.6 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Antifungal_prot PF11402.8 KFM70871.1 - 3.7 7.9 5.9 54 4.1 0.1 3.7 4 0 0 4 4 4 0 Antifungal protein UQ_con PF00179.26 KFM70872.1 - 4.7e-50 168.9 0.0 5.3e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UPF0121 PF03661.13 KFM70873.1 - 6.5e-83 277.8 11.3 7.4e-83 277.6 11.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) SHP PF03579.13 KFM70873.1 - 1.1 9.3 5.6 0.66 10.0 0.8 2.9 2 1 0 2 2 2 0 Small hydrophobic protein DDE_3 PF13358.6 KFM70874.1 - 0.00024 20.9 0.0 0.00027 20.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_2 PF07727.14 KFM70876.1 - 5.9e-06 26.1 0.1 6.2e-06 26.0 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Isochorismatase PF00857.20 KFM70878.1 - 7.8e-29 101.1 0.3 1.4e-28 100.2 0.3 1.4 1 1 0 1 1 1 1 Isochorismatase family EF-hand_1 PF00036.32 KFM70878.1 - 2e-05 23.8 2.5 7.5e-05 22.0 0.2 2.9 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 KFM70878.1 - 4.3e-05 22.8 2.7 5e-05 22.6 0.1 2.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KFM70878.1 - 0.00017 21.2 0.1 0.00083 19.1 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFM70878.1 - 0.0016 18.8 0.5 0.004 17.6 0.5 1.8 1 1 0 1 1 1 1 EF-hand domain pair Ig_2 PF13895.6 KFM70879.1 - 2.8e-05 24.3 0.1 0.00014 22.2 0.0 2.1 2 1 1 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM70879.1 - 5.1e-05 23.3 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM70879.1 - 0.00051 20.6 0.1 0.0018 18.8 0.0 1.9 1 1 1 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM70879.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin V-set domain DDE_3 PF13358.6 KFM70880.1 - 5.1e-16 58.7 0.1 5.6e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70880.1 - 6.2e-16 58.4 6.5 1.4e-15 57.3 6.5 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM70880.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM70880.1 - 0.0022 17.7 0.1 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM70880.1 - 0.014 15.6 0.1 0.064 13.4 0.1 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM70880.1 - 0.03 14.3 2.6 0.034 14.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM70880.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KFM70881.1 - 1.7e-16 60.2 2.2 3.8e-16 59.1 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70881.1 - 7.7e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70883.1 - 2.4e-16 59.7 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70883.1 - 2.3e-13 50.1 0.0 3.7e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM70884.1 - 2e-15 56.8 0.0 3.5e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70884.1 - 1.6e-10 41.0 1.0 2.6e-10 40.4 1.0 1.4 1 0 0 1 1 1 1 Transposase Orthopox_A5L PF06193.11 KFM70884.1 - 0.12 11.7 0.2 0.62 9.5 0.0 1.9 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like DDE_Tnp_1_7 PF13843.6 KFM70885.1 - 5.8e-80 269.2 0.9 7.5e-80 268.9 0.9 1.1 1 0 0 1 1 1 1 Transposase IS4 Pex14_N PF04695.13 KFM70885.1 - 0.0078 16.9 0.4 0.013 16.1 0.4 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region HTH_Tnp_Tc3_2 PF01498.18 KFM70886.1 - 2.6e-16 59.6 2.2 5.1e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70886.1 - 1e-13 51.3 0.0 1.9e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease LIM PF00412.22 KFM70887.1 - 2.8e-29 101.1 18.8 2.3e-14 53.3 2.4 2.5 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFM70887.1 - 3.6e-15 55.6 0.2 6.2e-15 54.8 0.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM70887.1 - 4.3e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain DDE_3 PF13358.6 KFM70888.1 - 2.3e-16 59.8 0.1 3e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70888.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM70889.1 - 4.2e-16 59.0 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70889.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70889.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70889.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70889.1 - 2 9.1 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain RRM_1 PF00076.22 KFM70891.1 - 3.8e-35 119.5 0.1 3.4e-17 62.0 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM70891.1 - 4.3e-08 33.2 0.1 0.0038 17.3 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM70891.1 - 0.00061 19.7 0.1 0.72 9.9 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 KFM70891.1 - 0.027 14.4 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 RL domain OB_RNB PF08206.11 KFM70891.1 - 0.032 13.9 0.4 0.84 9.4 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain DDE_3 PF13358.6 KFM70892.1 - 0.041 13.6 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease CRAL_TRIO PF00650.20 KFM70895.1 - 1e-32 113.0 1.4 1.5e-32 112.6 1.4 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM70895.1 - 5.6e-09 36.6 0.2 0.0012 19.4 0.0 2.4 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 KFM70895.1 - 2e-06 27.9 1.8 5e-06 26.6 1.8 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_hydro_18 PF00704.28 KFM70896.1 - 4.7e-26 92.3 0.1 5.2e-26 92.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KFM70897.1 - 1.2e-24 87.6 0.0 1.3e-24 87.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 KFM70897.1 - 0.0097 15.4 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_85 PF03644.13 KFM70897.1 - 0.019 14.4 0.0 0.023 14.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Prenyltrans PF00432.21 KFM70897.1 - 0.12 12.1 0.2 0.93 9.3 0.1 2.2 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat DUF2852 PF11014.8 KFM70897.1 - 0.13 12.4 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DDE_3 PF13358.6 KFM70898.1 - 1.2e-16 60.7 0.1 1.3e-15 57.5 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70898.1 - 1.5e-10 41.2 1.0 2.8e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Bcl-2 PF00452.19 KFM70900.1 - 5.5e-10 39.8 0.1 8.6e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family DDE_3 PF13358.6 KFM70902.1 - 1.8e-09 37.5 0.0 2.4e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM70905.1 - 1.2e-16 60.8 0.1 1.4e-15 57.3 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70905.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase AntA PF08346.12 KFM70905.1 - 0.14 12.7 0.7 0.71 10.5 0.2 2.1 2 0 0 2 2 2 0 AntA/AntB antirepressor HTH_Tnp_Tc3_2 PF01498.18 KFM70906.1 - 1.7e-16 60.2 2.2 4e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70906.1 - 1.3e-13 50.9 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Deltameth_res PF16020.5 KFM70907.1 - 9.7e-06 25.4 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Deltamethrin resistance EGF_3 PF12947.7 KFM70909.1 - 5.1e-12 45.8 159.3 2.2e-05 24.6 2.4 14.9 12 3 1 14 14 14 9 EGF domain EGF_CA PF07645.15 KFM70909.1 - 2.5e-11 43.6 17.6 2e-07 31.1 4.0 14.0 10 4 4 14 14 14 4 Calcium-binding EGF domain EGF PF00008.27 KFM70909.1 - 9.8e-09 35.4 18.2 2.3e-06 27.8 6.7 15.0 12 3 0 12 12 12 6 EGF-like domain cEGF PF12662.7 KFM70909.1 - 7.3e-05 22.6 95.4 0.0001 22.2 1.2 11.7 11 0 0 11 11 11 6 Complement Clr-like EGF-like hEGF PF12661.7 KFM70909.1 - 0.00016 22.2 7.0 0.00016 22.2 7.0 15.6 14 0 0 14 14 14 7 Human growth factor-like EGF FXa_inhibition PF14670.6 KFM70909.1 - 0.0026 18.0 7.4 0.0026 18.0 7.4 13.2 9 3 3 12 12 12 3 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KFM70909.1 - 0.51 10.7 124.3 0.13 12.6 1.7 13.3 13 0 0 13 13 13 0 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 KFM70909.1 - 3.6 7.7 156.9 0.071 13.2 6.1 14.0 13 1 0 13 13 13 0 MSP1 EGF domain 1 EGF_CA PF07645.15 KFM70911.1 - 1.9e-11 44.0 2.6 1.9e-11 44.0 2.6 3.2 2 1 1 3 3 3 1 Calcium-binding EGF domain cEGF PF12662.7 KFM70911.1 - 1.8e-07 31.0 8.6 2.2e-05 24.3 1.3 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFM70911.1 - 9.5e-07 28.9 27.3 1.8e-06 28.0 5.6 3.0 2 1 1 3 3 3 2 EGF domain EGF PF00008.27 KFM70911.1 - 6.6e-06 26.3 29.9 9e-06 25.9 8.2 3.6 2 1 1 3 3 3 1 EGF-like domain FXa_inhibition PF14670.6 KFM70911.1 - 3e-05 24.2 21.0 0.0013 19.0 4.9 2.6 2 1 0 2 2 2 2 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KFM70911.1 - 6.6e-05 23.1 15.9 0.0026 18.0 1.1 2.5 3 0 0 3 3 3 2 Pvs28 EGF domain hEGF PF12661.7 KFM70911.1 - 0.12 13.1 5.2 0.12 13.1 5.2 4.4 3 1 1 4 4 4 0 Human growth factor-like EGF EGF_3 PF12947.7 KFM70912.1 - 8e-06 25.9 27.9 0.00044 20.4 0.6 33.1 31 4 2 34 34 34 17 EGF domain EGF PF00008.27 KFM70912.1 - 0.00058 20.1 7.1 0.00058 20.1 7.1 38.1 32 10 6 38 38 38 12 EGF-like domain EGF_CA PF07645.15 KFM70914.1 - 1e-22 80.0 33.1 5.8e-10 39.2 2.9 17.4 11 7 6 17 17 17 6 Calcium-binding EGF domain cEGF PF12662.7 KFM70914.1 - 2.4e-12 46.5 101.9 0.00012 21.9 0.4 13.4 13 0 0 13 13 13 7 Complement Clr-like EGF-like EGF_3 PF12947.7 KFM70914.1 - 6.2e-11 42.3 26.8 3.1e-06 27.3 4.9 16.5 15 3 2 17 17 17 10 EGF domain EGF PF00008.27 KFM70914.1 - 3.7e-06 27.1 222.3 0.0012 19.1 10.0 17.2 16 4 0 16 16 16 9 EGF-like domain hEGF PF12661.7 KFM70914.1 - 5.6e-05 23.6 34.3 0.0011 19.5 8.0 16.2 16 1 1 17 17 17 5 Human growth factor-like EGF EB PF01683.18 KFM70914.1 - 0.00069 19.8 33.9 0.0076 16.5 4.0 16.5 3 3 11 14 14 14 6 EB module Plasmod_Pvs28 PF06247.11 KFM70914.1 - 0.0059 16.9 2.1 0.0059 16.9 2.1 13.2 13 1 0 13 13 13 6 Pvs28 EGF domain FXa_inhibition PF14670.6 KFM70914.1 - 0.007 16.6 22.5 0.0099 16.1 4.0 15.3 11 4 2 13 13 13 6 Coagulation Factor Xa inhibitory site CNH PF00780.22 KFM70915.1 - 2.9e-42 145.2 0.1 8.7e-42 143.6 0.1 1.8 1 0 0 1 1 1 1 CNH domain PH PF00169.29 KFM70915.1 - 5e-06 27.0 0.1 5e-06 27.0 0.1 3.6 4 0 0 4 4 4 1 PH domain C1_1 PF00130.22 KFM70915.1 - 7.9e-06 25.7 11.4 2e-05 24.4 11.4 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 KFM70916.1 - 3e-62 210.4 0.0 3.8e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM70916.1 - 5.8e-31 107.7 0.0 7.7e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM70916.1 - 2.2e-12 46.9 0.0 4.5e-11 42.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFM70916.1 - 1.2e-06 27.8 0.1 1.5e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 KFM70916.1 - 4.1e-05 24.2 0.7 0.00012 22.7 0.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KFM70916.1 - 9.5e-05 21.3 0.0 0.0002 20.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFM70916.1 - 0.00026 20.4 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFM70916.1 - 0.0076 15.3 0.3 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.23 KFM70916.1 - 0.011 15.7 0.1 0.025 14.5 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAST_1 PF06743.15 KFM70916.1 - 0.054 13.4 0.2 0.94 9.5 0.0 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 HAP1_N PF04849.13 KFM70917.1 - 8.8e-08 31.7 2.3 8.8e-08 31.7 2.3 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region INPP5B_PH PF16776.5 KFM70917.1 - 0.0066 16.2 0.1 0.0069 16.1 0.1 1.1 1 0 0 1 1 1 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Spherulin4 PF12138.8 KFM70917.1 - 0.082 12.5 0.2 0.088 12.4 0.2 1.0 1 0 0 1 1 1 0 Spherulation-specific family 4 Ras PF00071.22 KFM70918.1 - 2e-60 203.0 0.4 2.9e-60 202.5 0.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM70918.1 - 8e-35 119.7 1.5 9.3e-35 119.4 0.2 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM70918.1 - 3.6e-16 59.1 0.7 3.6e-16 59.1 0.7 1.7 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM70918.1 - 2.1e-07 30.7 1.2 9.4e-07 28.6 0.2 2.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM70918.1 - 6.7e-06 26.2 0.9 2e-05 24.7 0.1 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM70918.1 - 6.9e-05 22.8 1.5 0.029 14.3 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFM70918.1 - 8.7e-05 22.0 1.1 0.00028 20.3 1.1 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KFM70918.1 - 0.0002 20.9 0.6 0.001 18.7 0.6 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KFM70918.1 - 0.0015 18.2 0.2 0.1 12.4 0.2 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KFM70918.1 - 0.0018 18.7 0.0 0.004 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM70918.1 - 0.005 17.1 0.1 0.017 15.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFM70918.1 - 0.0064 16.2 2.2 0.047 13.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFM70918.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KFM70918.1 - 0.025 13.6 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 KFM70918.1 - 0.038 14.0 0.2 0.087 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KFM70918.1 - 0.038 13.4 0.2 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 KFM70918.1 - 0.053 13.1 0.1 0.3 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFM70918.1 - 0.055 14.0 4.1 0.1 13.1 4.1 1.3 1 1 0 1 1 1 0 AAA domain CBM9_2 PF16011.5 KFM70918.1 - 0.081 12.6 0.3 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Carbohydrate-binding family 9 AAA PF00004.29 KFM70918.1 - 0.1 13.0 0.3 1.3 9.5 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KFM70918.1 - 0.7 10.4 4.7 1.9 9.0 4.7 1.9 1 1 0 1 1 1 0 ABC transporter RabGAP-TBC PF00566.18 KFM70919.1 - 3.1e-13 49.9 1.1 4.4e-13 49.4 1.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mhr1 PF12829.7 KFM70920.1 - 0.085 13.0 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination MatP_C PF17414.2 KFM70922.1 - 0.0017 18.5 0.5 0.59 10.4 0.0 2.1 1 1 1 2 2 2 2 MatP C-terminal ribbon-helix-helix domain TcpA PF05946.12 KFM70926.1 - 0.0033 17.5 3.0 5.6 7.1 0.1 3.5 1 1 2 3 3 3 3 Toxin-coregulated pilus subunit TcpA Bravo_FIGEY PF13882.6 KFM70926.1 - 0.077 14.4 2.8 0.3 12.5 0.1 2.8 2 1 1 3 3 3 0 Bravo-like intracellular region EcsC PF12787.7 KFM70928.1 - 0.015 15.0 0.9 43 3.7 0.9 8.0 1 0 0 1 1 1 0 EcsC protein family DivIC PF04977.15 KFM70928.1 - 0.23 11.3 1.0 0.34 10.7 1.0 1.1 1 0 0 1 1 1 0 Septum formation initiator EzrA PF06160.12 KFM70928.1 - 0.26 9.4 0.6 0.37 8.9 0.6 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TPP_enzyme_N PF02776.18 KFM70929.1 - 4.8e-12 45.8 0.3 5.2e-12 45.7 0.3 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF2007 PF09413.10 KFM70929.1 - 0.0042 17.2 0.1 0.38 10.9 0.0 2.2 1 1 1 2 2 2 2 Putative prokaryotic signal transducing protein NMT1_3 PF16868.5 KFM70929.1 - 0.01 15.3 0.1 0.01 15.3 0.1 1.0 1 0 0 1 1 1 0 NMT1-like family TPP_enzyme_M PF00205.22 KFM70930.1 - 1e-28 99.8 0.0 3.8e-28 97.9 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFM70930.1 - 5.2e-25 88.0 0.0 1.1e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 KFM70930.1 - 1.9e-15 56.9 0.0 2.5e-14 53.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PP2C PF00481.21 KFM70932.1 - 5e-32 111.6 9.7 5.5e-25 88.5 0.2 2.9 3 0 0 3 3 3 2 Protein phosphatase 2C Caldesmon PF02029.15 KFM70932.1 - 0.01 14.6 29.3 0.015 14.1 29.3 1.1 1 0 0 1 1 1 0 Caldesmon Mitofilin PF09731.9 KFM70932.1 - 0.012 14.6 15.9 0.015 14.2 15.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PIG-S PF10510.9 KFM70932.1 - 0.11 11.3 5.0 0.15 10.9 5.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein TFIIF_alpha PF05793.12 KFM70932.1 - 0.15 10.7 25.9 0.22 10.1 25.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Stimulus_sens_1 PF13756.6 KFM70932.1 - 0.15 12.7 2.9 0.58 10.8 2.9 2.0 1 0 0 1 1 1 0 Stimulus-sensing domain Borrelia_P83 PF05262.11 KFM70932.1 - 0.49 8.8 16.8 0.63 8.5 16.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SID-1_RNA_chan PF13965.6 KFM70932.1 - 0.64 8.4 5.0 0.83 8.0 5.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Mpp10 PF04006.12 KFM70932.1 - 0.82 8.0 32.9 1.2 7.5 32.9 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 KFM70932.1 - 0.99 8.8 31.4 1.6 8.1 31.4 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KFM70932.1 - 1.4 7.1 19.5 2 6.6 19.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KFM70932.1 - 2.6 6.1 12.0 2.9 5.9 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BUD22 PF09073.10 KFM70932.1 - 4.3 6.6 25.8 6.3 6.0 25.8 1.2 1 0 0 1 1 1 0 BUD22 SLC12 PF03522.15 KFM70932.1 - 4.5 6.2 13.8 6.2 5.7 13.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Mem_trans PF03547.18 KFM70932.1 - 6.9 4.9 6.5 8.6 4.6 6.5 1.1 1 0 0 1 1 1 0 Membrane transport protein HTH_Tnp_Tc3_2 PF01498.18 KFM70933.1 - 2.7e-16 59.6 3.2 4.1e-16 59.0 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70933.1 - 8.6e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase_Tyr PF07714.17 KFM70934.1 - 7.5e-13 48.4 0.0 8.9e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM70934.1 - 4.1e-10 39.5 0.0 5.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFM70934.1 - 0.0058 16.0 0.0 0.007 15.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DUF1593 PF07632.11 KFM70934.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) RBD PF02196.15 KFM70935.1 - 2.7e-27 94.7 0.0 4.1e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 KFM70935.1 - 5.7e-11 42.1 9.3 1.1e-10 41.3 9.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 KFM70935.1 - 0.00044 20.5 7.4 0.001 19.3 7.4 1.6 1 0 0 1 1 1 1 RING-like domain C1_2 PF03107.16 KFM70935.1 - 0.005 17.1 5.4 0.005 17.1 5.4 1.7 2 0 0 2 2 2 1 C1 domain TUG-UBL1 PF11470.8 KFM70935.1 - 0.0074 16.5 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain ubiquitin PF00240.23 KFM70936.1 - 1.9e-34 117.2 0.4 2.3e-34 116.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KFM70936.1 - 4.5e-29 100.1 11.6 7e-29 99.5 11.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KFM70936.1 - 1.8e-16 59.8 0.5 2.3e-16 59.4 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFM70936.1 - 1.5e-05 25.4 0.1 5.3e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KFM70936.1 - 0.003 17.9 0.1 0.0048 17.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KFM70936.1 - 0.0049 16.8 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFM70936.1 - 0.0064 16.6 0.1 0.012 15.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KFM70936.1 - 0.014 15.5 1.2 3.9 7.6 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 KFM70936.1 - 0.03 14.9 0.0 0.04 14.5 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain DIM1 PF02966.16 KFM70937.1 - 2.1e-43 147.3 0.3 2.3e-43 147.1 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 EF-hand_1 PF00036.32 KFM70938.1 - 5.7e-20 69.3 6.8 0.0055 16.2 0.0 6.0 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 KFM70938.1 - 3.4e-19 69.1 6.9 3.9e-08 33.6 0.3 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFM70938.1 - 6.5e-15 53.9 5.8 0.00052 19.4 0.0 5.7 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KFM70938.1 - 5e-13 47.8 4.7 0.044 13.7 0.1 5.6 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 KFM70938.1 - 8.2e-09 35.2 4.9 0.0086 15.9 0.1 5.4 5 0 0 5 5 5 3 EF-hand domain pair Dockerin_1 PF00404.18 KFM70938.1 - 0.0034 17.6 0.0 1.6 9.0 0.0 3.5 3 0 0 3 3 3 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KFM70938.1 - 0.0046 17.2 9.8 0.25 11.7 3.0 3.6 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Glyco_hydro_71 PF03659.14 KFM70938.1 - 0.0051 15.7 0.1 0.007 15.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DNA_primase_S PF01896.19 KFM70939.1 - 1.9e-13 50.9 0.0 2e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 DNA primase small subunit DUF2471 PF10616.9 KFM70939.1 - 0.076 13.6 0.0 0.085 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2471) DNA_primase_S PF01896.19 KFM70940.1 - 2.4e-39 135.2 0.3 4.5e-39 134.3 0.3 1.4 1 0 0 1 1 1 1 DNA primase small subunit Sugar_tr PF00083.24 KFM70941.1 - 2.8e-36 125.4 7.6 4e-36 124.8 7.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM70941.1 - 2.2e-28 99.2 13.7 2.2e-28 99.2 13.7 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily PAX PF00292.18 KFM70944.1 - 2.2e-07 30.8 0.0 2.6e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.6 KFM70944.1 - 7.7e-05 22.7 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KFM70944.1 - 0.0009 19.0 0.1 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70944.1 - 0.0021 17.8 0.1 0.0021 17.8 0.1 1.9 2 1 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM70944.1 - 0.015 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_3 PF01381.22 KFM70944.1 - 0.057 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_32 PF13565.6 KFM70944.1 - 0.068 13.8 2.6 0.11 13.1 2.6 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 KFM70944.1 - 0.076 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Transposase I-set PF07679.16 KFM70946.1 - 5.8e-08 32.7 0.0 6.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM70946.1 - 4.8e-06 27.1 0.0 5.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM70946.1 - 0.00021 21.4 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM70946.1 - 0.00037 20.6 0.0 0.0004 20.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM70946.1 - 0.0035 17.6 0.0 0.0042 17.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFM70946.1 - 0.056 13.0 0.1 0.12 12.0 0.1 1.6 1 1 0 1 1 1 0 Immunoglobulin domain Seryl_tRNA_N PF02403.22 KFM70947.1 - 0.12 12.6 3.0 0.21 11.8 1.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Uds1 PF15456.6 KFM70947.1 - 2 8.6 15.8 0.13 12.4 1.7 3.0 2 1 0 2 2 2 0 Up-regulated During Septation tRNA-synt_His PF13393.6 KFM70948.1 - 1.2e-19 70.8 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2 PF00152.20 KFM70948.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KFM70948.1 - 0.03 13.8 0.0 0.063 12.7 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) Tubulin PF00091.25 KFM70949.1 - 3.9e-60 203.4 0.0 7.1e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM70949.1 - 5.1e-43 146.2 0.1 8.1e-43 145.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFM70949.1 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFM70949.1 - 0.015 14.5 0.1 0.033 13.4 0.0 1.6 2 0 0 2 2 2 0 Tubulin like Transposase_1 PF01359.18 KFM70950.1 - 9.1e-22 76.7 0.1 3.2e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 Transposase (partial DDE domain) PRE_C2HC PF07530.11 KFM70950.1 - 0.11 12.6 1.3 0.25 11.5 1.3 1.6 1 0 0 1 1 1 0 Associated with zinc fingers MBOAT PF03062.19 KFM70951.1 - 8.4e-51 173.3 3.9 8.4e-51 173.3 3.9 1.6 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DDE_3 PF13358.6 KFM70952.1 - 0.0033 17.2 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease IPK PF03770.16 KFM70953.1 - 4.8e-38 131.0 0.1 6.4e-38 130.6 0.1 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF2358 PF10184.9 KFM70954.1 - 6.5e-25 87.6 3.6 9.3e-25 87.1 0.7 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) BTB PF00651.31 KFM70955.1 - 6.1e-40 135.9 2.2 2.6e-26 92.0 0.3 2.8 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM70955.1 - 4.5e-05 23.5 0.1 0.035 14.2 0.0 3.0 2 0 0 2 2 2 2 BTB And C-terminal Kelch MATH PF00917.26 KFM70955.1 - 5.3e-05 23.3 0.1 0.00021 21.4 0.1 2.0 1 0 0 1 1 1 1 MATH domain BTB_2 PF02214.22 KFM70955.1 - 0.0016 18.7 0.1 3.4 8.1 0.0 2.9 2 0 0 2 2 2 2 BTB/POZ domain BTB_3 PF16017.5 KFM70955.1 - 0.024 14.7 1.0 4.1 7.6 0.1 3.2 2 1 1 3 3 3 0 BTB/POZ domain Tnp_P_element PF12017.8 KFM70956.1 - 5.4e-59 199.3 5.4 5.4e-59 199.3 5.4 1.9 1 1 1 2 2 2 1 Transposase protein Tnp_P_element_C PF12596.8 KFM70956.1 - 0.0053 17.3 1.5 0.018 15.6 0.0 2.5 3 0 0 3 3 3 1 87kDa Transposase DUF4817 PF16087.5 KFM70956.1 - 0.093 12.6 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) TMF_TATA_bd PF12325.8 KFM70956.1 - 0.17 12.1 5.3 0.49 10.6 5.3 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Occludin_ELL PF07303.13 KFM70956.1 - 3.2 8.5 11.9 3.7 8.3 9.1 2.6 2 1 1 3 3 3 0 Occludin homology domain Ig_3 PF13927.6 KFM70957.1 - 0.00015 22.3 0.0 0.00025 21.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM70957.1 - 0.0002 21.5 0.0 0.00026 21.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM70957.1 - 0.00024 21.3 0.0 0.00029 21.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFM70957.1 - 0.00067 19.7 0.0 0.00084 19.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain HTH_Tnp_Tc3_2 PF01498.18 KFM70958.1 - 2.2e-16 59.9 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM70958.1 - 9.5e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CRF PF00473.17 KFM70959.1 - 2.9e-10 40.0 4.7 4.9e-10 39.3 4.7 1.4 1 0 0 1 1 1 1 Corticotropin-releasing factor family TRAM_LAG1_CLN8 PF03798.16 KFM70960.1 - 4.7e-08 33.0 14.2 5.3e-08 32.8 14.2 1.0 1 0 0 1 1 1 1 TLC domain KASH_CCD PF14662.6 KFM70961.1 - 0.00066 19.6 15.3 0.001 18.9 15.3 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH PAD PF03068.15 KFM70961.1 - 0.1 11.6 1.3 0.14 11.2 1.1 1.3 1 1 0 1 1 1 0 Protein-arginine deiminase (PAD) FapA PF03961.13 KFM70961.1 - 0.37 9.3 6.6 0.43 9.1 6.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HMMR_C PF15908.5 KFM70961.1 - 0.49 10.7 9.3 0.73 10.1 5.5 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal GIT_CC PF16559.5 KFM70961.1 - 1.1 9.2 16.7 0.06 13.2 4.2 2.8 1 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PCRF PF03462.18 KFM70961.1 - 1.8 8.4 6.9 2.6 7.9 6.9 1.1 1 0 0 1 1 1 0 PCRF domain zf-C4H2 PF10146.9 KFM70961.1 - 2.6 8.3 10.0 4.4 7.6 9.8 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein ZapB PF06005.12 KFM70961.1 - 4.1 7.9 21.6 0.29 11.6 8.4 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF2968 PF11180.8 KFM70961.1 - 4.7 6.8 11.1 6.6 6.3 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) RP-C_C PF11800.8 KFM70962.1 - 0.018 15.2 1.5 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF3704 PF12488.8 KFM70963.1 - 0.041 13.5 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Spermine_synth PF01564.17 KFM70964.1 - 2.8e-32 111.7 0.1 5.5e-32 110.7 0.0 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KFM70964.1 - 8.2e-11 41.6 0.0 1.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KFM70964.1 - 0.00027 21.6 0.0 0.00053 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM70964.1 - 0.004 17.9 0.0 0.011 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 KFM70964.1 - 0.016 14.5 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_31 PF13847.6 KFM70964.1 - 0.048 13.5 0.2 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain ELO PF01151.18 KFM70965.1 - 2.7e-38 131.9 17.1 3.4e-38 131.6 17.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MWFE PF15879.5 KFM70965.1 - 0.14 12.4 0.1 0.37 11.0 0.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit ELO PF01151.18 KFM70966.1 - 5.1e-12 45.9 0.4 6.1e-12 45.6 0.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family CTD PF12815.7 KFM70967.1 - 5.5e-08 33.3 43.7 1.2e-05 25.8 40.2 4.1 2 1 0 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 KFM70967.1 - 1.7e-05 24.6 3.7 0.0031 17.4 0.1 3.2 3 0 0 3 3 3 2 KOW motif DUF3912 PF13051.6 KFM70967.1 - 0.0002 21.5 0.0 0.00039 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3912) Cg6151-P PF10233.9 KFM70968.1 - 9.2e-27 93.6 6.4 1.1e-26 93.4 6.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Glyco_hydro_47 PF01532.20 KFM70969.1 - 0.063 12.2 0.0 0.072 12.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 DUF1327 PF07041.11 KFM70969.1 - 0.078 13.0 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1327) Ku_PK_bind PF08785.11 KFM70970.1 - 0.013 15.7 1.7 2.9 8.1 0.0 3.6 2 1 2 4 4 4 0 Ku C terminal domain like DOCK-C2 PF14429.6 KFM70971.1 - 6.7e-10 39.1 0.3 8.7e-10 38.7 0.3 1.2 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Cse1 PF08506.10 KFM70971.1 - 0.0013 17.6 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Cse1 DOCK_N PF16172.5 KFM70972.1 - 3.4e-109 365.2 0.0 4.1e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KFM70972.1 - 5.6e-17 62.2 0.1 7e-16 58.6 0.0 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_2 PF07653.17 KFM70972.1 - 5.8e-08 32.3 0.1 1.3e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFM70972.1 - 1.5e-07 31.1 0.0 2.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM70972.1 - 9.8e-07 28.3 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Ribosomal_L26 PF16906.5 KFM70972.1 - 0.029 14.8 0.1 0.29 11.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal BPL_LplA_LipB PF03099.19 KFM70974.1 - 0.051 13.5 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family LCE6A PF15858.5 KFM70974.1 - 0.096 13.4 0.9 0.15 12.9 0.9 1.2 1 0 0 1 1 1 0 Late cornified envelope protein 6A family PPDK_N PF01326.19 KFM70975.1 - 2e-56 191.7 0.0 3.5e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 KFM70975.1 - 1.7e-19 69.3 0.1 6.9e-19 67.4 0.0 2.1 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain Peptidase_C101 PF16218.5 KFM70975.1 - 0.038 13.3 0.2 0.061 12.6 0.2 1.3 1 0 0 1 1 1 0 Peptidase family C101 MIEAP PF16026.5 KFM70978.1 - 1.4e-60 204.9 0.5 1.4e-59 201.7 0.0 2.4 2 0 0 2 2 2 1 Mitochondria-eating protein ADIP PF11559.8 KFM70978.1 - 0.0048 17.0 2.8 0.011 15.8 1.9 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 KFM70978.1 - 0.038 13.3 1.2 0.089 12.1 1.2 1.5 1 0 0 1 1 1 0 FAM76 protein HTH_19 PF12844.7 KFM70978.1 - 0.051 13.6 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_MLP1_2 PF07926.12 KFM70978.1 - 0.065 13.3 2.9 0.2 11.7 2.9 1.8 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.6 KFM70978.1 - 0.083 13.3 0.0 0.34 11.4 0.0 2.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.6 KFM70978.1 - 0.23 11.5 3.1 0.52 10.3 1.7 2.3 2 0 0 2 2 2 0 FlxA-like protein DivIC PF04977.15 KFM70978.1 - 0.6 9.9 2.7 2.1 8.1 1.7 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF3847 PF12958.7 KFM70978.1 - 1 9.5 7.9 0.35 11.0 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) LIM_bind PF01803.16 KFM70980.1 - 1.9e-58 197.8 0.0 3.9e-56 190.3 0.0 2.4 1 1 0 1 1 1 1 LIM-domain binding protein LID PF17916.1 KFM70980.1 - 1.1e-19 69.7 2.6 2.2e-19 68.8 2.6 1.5 1 0 0 1 1 1 1 LIM interaction domain (LID) DUF4371 PF14291.6 KFM70981.1 - 3.4e-10 40.0 0.1 1.2e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM70981.1 - 0.0025 17.3 0.8 0.0025 17.3 0.8 2.3 2 1 0 2 2 2 1 Zinc-finger C2H2-type An_peroxidase PF03098.15 KFM70982.1 - 0 1276.4 0.0 1.5e-196 654.1 0.0 2.1 2 0 0 2 2 2 2 Animal haem peroxidase TetR_C_30 PF17939.1 KFM70982.1 - 0.047 13.9 0.0 42 4.4 0.0 3.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM70983.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM70983.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM70983.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM70983.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM70983.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain eIF3g PF12353.8 KFM70985.1 - 0.0015 18.9 0.0 0.0017 18.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Y_phosphatase PF00102.27 KFM70986.1 - 8.5e-114 379.0 2.1 8.9e-76 254.5 0.5 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KFM70986.1 - 0.019 15.1 0.0 0.095 12.8 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFM70986.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3119 PF11317.8 KFM70986.1 - 0.019 15.2 0.1 0.061 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3119) Methyltransf_PK PF05891.12 KFM70986.1 - 0.05 13.1 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DSPc PF00782.20 KFM70986.1 - 0.14 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DDE_3 PF13358.6 KFM70987.1 - 3.4e-16 59.3 0.1 3e-15 56.2 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM70987.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase USP8_dimer PF08969.11 KFM70990.1 - 1e-16 61.1 1.5 1.8e-16 60.3 0.2 2.1 2 1 0 2 2 2 1 USP8 dimerisation domain JAB PF01398.21 KFM70990.1 - 3.9e-16 59.1 0.0 3.9e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KFM70990.1 - 1.4e-06 28.1 0.1 3.4e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RPN2_C PF18004.1 KFM70990.1 - 0.24 11.3 8.9 0.38 10.7 8.9 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain MRP-S33 PF08293.11 KFM70991.1 - 2.4e-24 85.4 0.7 2.7e-24 85.2 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Nucleoporin_N PF08801.11 KFM70992.1 - 0.00041 19.2 0.0 0.00055 18.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KFM70993.1 - 7.7e-30 104.2 15.7 2.9e-29 102.3 11.4 2.6 2 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Se-cys_synth_N PF12390.8 KFM70994.1 - 0.04 14.1 0.1 0.049 13.9 0.1 1.1 1 0 0 1 1 1 0 Selenocysteine synthase N terminal DUF4407 PF14362.6 KFM70996.1 - 0.62 9.4 1.5 1.8 7.9 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pheromone PF08015.11 KFM70996.1 - 3.1 8.9 11.7 0.35 11.9 4.3 3.3 2 0 0 2 2 2 0 Fungal mating-type pheromone gp37_C PF12604.8 KFM70997.1 - 0.14 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Tail fibre protein gp37 C terminal Methyltr_RsmB-F PF01189.17 KFM70998.1 - 7.7e-39 133.4 0.0 3.5e-38 131.3 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFM70998.1 - 0.0001 22.5 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase HTH_Tnp_Tc3_2 PF01498.18 KFM71001.1 - 7.2e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71001.1 - 7.3e-16 58.2 0.1 8.8e-15 54.7 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71001.1 - 0.00067 20.2 1.1 0.00067 20.2 1.1 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71001.1 - 0.0014 18.3 0.1 0.069 13.0 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM71001.1 - 0.02 14.9 2.6 0.02 14.9 0.3 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 KFM71001.1 - 0.022 14.9 0.1 0.096 12.8 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM71002.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71002.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Neur_chan_memb PF02932.16 KFM71003.1 - 3e-18 66.7 6.2 3.9e-18 66.4 6.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM71003.1 - 5.9e-09 35.7 0.0 7.3e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain ANAPC4_WD40 PF12894.7 KFM71004.1 - 1.5e-10 41.2 0.3 0.0089 16.3 0.0 5.3 4 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM71004.1 - 2.1e-05 25.2 9.8 0.35 11.8 0.0 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat KH_6 PF15985.5 KFM71004.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 KH domain IKI3 PF04762.12 KFM71004.1 - 0.053 11.5 0.0 5.1 5.0 0.0 2.6 2 1 0 3 3 3 0 IKI3 family Coatomer_WDAD PF04053.14 KFM71006.1 - 0.0003 20.0 0.1 0.00051 19.2 0.1 1.4 1 0 0 1 1 1 1 Coatomer WD associated region Clathrin PF00637.20 KFM71006.1 - 0.0017 18.2 2.5 0.004 17.0 0.1 2.5 2 1 2 4 4 4 1 Region in Clathrin and VPS TPR_19 PF14559.6 KFM71006.1 - 0.04 14.4 3.2 19 5.8 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM71006.1 - 0.41 10.9 12.8 0.67 10.2 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM71006.1 - 1 9.3 0.0 1 9.3 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DZR PF12773.7 KFM71007.1 - 0.0003 20.7 4.7 0.0061 16.6 4.7 2.4 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KFM71007.1 - 0.001 18.7 8.3 0.0036 17.0 2.2 3.6 3 0 0 3 3 3 1 zinc-ribbon domain Cript PF10235.9 KFM71007.1 - 0.0028 18.2 2.8 0.0028 18.2 2.8 1.9 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT Phage_connect_1 PF05135.13 KFM71007.1 - 0.069 13.7 0.3 0.17 12.4 0.3 1.8 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein Clathrin PF00637.20 KFM71007.1 - 0.24 11.3 2.1 6.5 6.6 0.0 3.2 3 1 1 4 4 4 0 Region in Clathrin and VPS DUF2616 PF11077.8 KFM71007.1 - 0.3 10.8 7.8 9.5 5.9 7.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2616) TPR_19 PF14559.6 KFM71007.1 - 0.39 11.3 2.3 21 5.7 0.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2089 PF09862.9 KFM71007.1 - 0.79 9.8 3.7 2.6 8.1 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2089) Rad50_zn_hook PF04423.14 KFM71007.1 - 0.93 9.4 7.6 13 5.7 0.5 3.7 2 1 1 3 3 3 0 Rad50 zinc hook motif zf-Di19 PF05605.12 KFM71007.1 - 0.96 9.8 16.3 2.7 8.4 8.3 3.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding ANAPC3 PF12895.7 KFM71007.1 - 1.2 9.4 4.9 2.9 8.2 0.3 3.7 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 zinc_ribbon_15 PF17032.5 KFM71007.1 - 1.5 9.6 7.5 0.2 12.4 1.0 2.6 2 1 1 3 3 3 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM71007.1 - 6.4 7.0 11.1 5.2 7.3 0.1 3.7 2 1 1 3 3 3 0 Zinc ribbon domain Ank_2 PF12796.7 KFM71008.1 - 3.3e-84 277.6 22.8 7.3e-15 55.3 0.4 8.1 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM71008.1 - 5.2e-73 240.5 26.6 1.3e-09 38.4 0.0 12.0 3 2 10 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 KFM71008.1 - 1.5e-64 211.7 32.7 6.8e-07 29.5 0.0 15.3 16 0 0 16 16 16 13 Ankyrin repeat Ank_5 PF13857.6 KFM71008.1 - 6.7e-62 204.7 21.0 2.4e-09 37.3 0.0 12.5 4 2 9 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM71008.1 - 2.6e-54 174.8 25.9 0.0012 19.1 0.0 16.3 16 0 0 16 16 16 13 Ankyrin repeat IQ PF00612.27 KFM71008.1 - 7.7e-05 22.2 4.8 0.02 14.6 0.6 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif NDK PF00334.19 KFM71009.1 - 1.6e-53 180.4 0.0 1.9e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Benyvirus_14KDa PF07255.11 KFM71009.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Benyvirus 14KDa protein Chitin_bind_4 PF00379.23 KFM71010.1 - 1.4e-07 31.9 6.1 3.2e-07 30.8 6.1 1.7 1 0 0 1 1 1 1 Insect cuticle protein Cadherin_5 PF17892.1 KFM71010.1 - 0.25 11.3 0.7 1.6 8.7 0.1 2.3 1 1 2 3 3 3 0 Cadherin-like domain CoA_binding PF02629.19 KFM71011.1 - 6.5e-31 106.9 1.2 6.5e-31 106.9 1.2 2.0 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 KFM71011.1 - 4.3e-22 78.6 0.4 8.7e-22 77.6 0.1 1.7 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 KFM71011.1 - 1.4e-07 31.4 0.0 2.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KFM71011.1 - 0.00016 22.1 0.0 0.00049 20.6 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Chitin_bind_4 PF00379.23 KFM71012.1 - 5.2e-07 30.1 1.0 8.6e-07 29.4 1.0 1.4 1 0 0 1 1 1 1 Insect cuticle protein GLTT PF01744.20 KFM71012.1 - 0.11 12.3 1.8 0.29 10.9 1.8 1.8 1 0 0 1 1 1 0 GLTT repeat (6 copies) Chitin_bind_4 PF00379.23 KFM71013.1 - 9e-08 32.5 0.5 1.4e-07 31.9 0.5 1.3 1 0 0 1 1 1 1 Insect cuticle protein GLTT PF01744.20 KFM71013.1 - 0.11 12.3 1.8 0.29 10.9 1.8 1.8 1 0 0 1 1 1 0 GLTT repeat (6 copies) Chitin_bind_4 PF00379.23 KFM71014.1 - 1.8e-08 34.8 0.6 2.9e-08 34.1 0.6 1.3 1 0 0 1 1 1 1 Insect cuticle protein GLTT PF01744.20 KFM71014.1 - 0.11 12.2 1.8 0.29 10.9 1.8 1.7 1 0 0 1 1 1 0 GLTT repeat (6 copies) Chitin_bind_4 PF00379.23 KFM71015.1 - 5.9e-08 33.1 0.7 9.8e-08 32.4 0.7 1.4 1 0 0 1 1 1 1 Insect cuticle protein GLTT PF01744.20 KFM71015.1 - 0.098 12.4 1.8 0.29 10.9 1.8 1.9 1 0 0 1 1 1 0 GLTT repeat (6 copies) RT_RNaseH_2 PF17919.1 KFM71016.1 - 1e-30 105.7 0.1 4.1e-30 103.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM71016.1 - 2.4e-29 102.5 0.3 6.1e-29 101.1 0.3 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM71016.1 - 3.4e-27 94.8 0.0 1.7e-26 92.5 0.0 2.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM71016.1 - 1.7e-18 66.4 0.0 5.5e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM71016.1 - 1.1e-16 61.1 0.0 3.2e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KFM71016.1 - 3.7e-06 27.1 0.4 8.6e-06 25.9 0.4 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Arc_C PF18162.1 KFM71016.1 - 0.00036 20.3 2.5 0.00052 19.8 0.4 2.4 3 0 0 3 3 3 1 Arc C-lobe Retrotrans_gag PF03732.17 KFM71016.1 - 0.00094 19.4 1.5 0.0063 16.8 0.0 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein BH4 PF02180.17 KFM71016.1 - 0.055 13.3 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 Bcl-2 homology region 4 DDE_Tnp_IS240 PF13610.6 KFM71016.1 - 0.075 13.3 1.6 0.2 11.9 0.2 2.5 2 0 0 2 2 2 0 DDE domain TRF PF08558.10 KFM71016.1 - 4.8 6.7 7.9 32 4.0 3.4 2.9 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) RT_RNaseH_2 PF17919.1 KFM71017.1 - 1.2e-30 105.4 0.0 3.4e-30 104.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM71017.1 - 4.3e-29 101.6 1.5 5e-29 101.4 0.3 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM71017.1 - 2.9e-27 95.0 0.0 1.4e-26 92.8 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM71017.1 - 1.6e-18 66.6 0.0 4.1e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM71017.1 - 8.5e-17 61.4 0.0 2.6e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFM71017.1 - 3.1e-06 27.3 0.4 7.3e-06 26.1 0.4 1.7 1 0 0 1 1 1 1 H2C2 zinc finger BH4 PF02180.17 KFM71017.1 - 0.046 13.5 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Bcl-2 homology region 4 DDE_Tnp_IS240 PF13610.6 KFM71017.1 - 0.14 12.4 3.0 0.17 12.1 0.2 2.6 2 0 0 2 2 2 0 DDE domain HTH_Tnp_Tc3_2 PF01498.18 KFM71018.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71018.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Chitin_bind_4 PF00379.23 KFM71019.1 - 1.1e-08 35.4 2.5 1.9e-08 34.7 2.5 1.3 1 0 0 1 1 1 1 Insect cuticle protein HTH_Tnp_Tc3_2 PF01498.18 KFM71022.1 - 7.7e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71022.1 - 2.7e-15 56.4 0.0 6.7e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71022.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71022.1 - 0.063 13.1 1.8 0.8 9.6 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HMG_box PF00505.19 KFM71024.1 - 2.4e-28 98.3 2.7 3.6e-28 97.8 2.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM71024.1 - 2.5e-11 44.0 1.0 4.3e-11 43.2 1.0 1.4 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.8 KFM71024.1 - 0.0023 19.0 0.3 0.0043 18.1 0.3 1.5 1 0 0 1 1 1 1 SOX transcription factor DUF4108 PF13390.6 KFM71025.1 - 0.2 11.6 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) zf-H2C2_2 PF13465.6 KFM71027.1 - 1.1e-73 240.6 136.7 2e-09 37.4 2.4 14.4 14 1 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71027.1 - 1.2e-33 113.7 148.7 2e-05 24.8 0.4 13.4 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71027.1 - 3.3e-33 111.5 132.1 0.00071 20.2 0.4 13.3 13 0 0 13 13 13 12 C2H2-type zinc finger zf-met PF12874.7 KFM71027.1 - 3.1e-17 62.3 131.7 0.027 14.9 0.2 13.4 13 0 0 13 13 13 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM71027.1 - 2.5e-13 49.6 119.3 0.019 15.0 3.9 13.8 13 1 0 13 13 13 10 C2H2-type zinc finger BolA PF01722.18 KFM71027.1 - 3.4e-06 27.2 20.0 1.2 9.5 0.1 7.1 2 1 4 6 6 6 4 BolA-like protein zf-H2C2_5 PF13909.6 KFM71027.1 - 4.7e-06 26.2 7.4 0.016 14.9 1.2 13.6 13 1 0 13 13 13 6 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFM71028.1 - 9.9e-12 44.7 7.6 1.3e-09 38.0 2.3 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71028.1 - 6.5e-09 35.8 7.7 3.4e-06 27.2 2.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71028.1 - 1.4e-06 28.6 7.2 0.00011 22.8 2.0 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM71028.1 - 8.8e-06 25.6 5.1 0.0045 16.9 0.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger ARS2 PF04959.13 KFM71028.1 - 0.003 18.0 2.0 0.003 18.0 2.0 1.1 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-HIT PF04438.16 KFM71028.1 - 0.0035 17.2 3.9 0.064 13.1 0.2 2.2 2 0 0 2 2 2 1 HIT zinc finger ZZ PF00569.17 KFM71028.1 - 0.0045 16.8 1.6 1.7 8.5 0.1 2.2 2 0 0 2 2 2 2 Zinc finger, ZZ type zf-met PF12874.7 KFM71028.1 - 0.0048 17.3 4.7 0.13 12.7 0.5 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_1 PF00130.22 KFM71028.1 - 0.015 15.2 2.5 0.18 11.7 2.6 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) VATC PF18716.1 KFM71028.1 - 0.02 14.7 2.8 0.14 12.1 0.4 2.1 2 0 0 2 2 2 0 Vms1-associating treble clef domain zf-C2HC_2 PF13913.6 KFM71028.1 - 0.044 13.7 6.2 0.068 13.1 1.0 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.15 KFM71028.1 - 0.048 13.7 4.5 1.8 8.6 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger Desulfoferrod_N PF06397.12 KFM71028.1 - 0.082 12.5 0.7 2.9 7.6 0.1 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-FCS PF06467.14 KFM71028.1 - 0.085 12.8 4.4 3.1 7.8 5.3 2.1 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.8 KFM71028.1 - 0.093 13.1 5.4 3 8.3 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM71028.1 - 0.13 12.1 3.4 3 7.7 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FYVE PF01363.21 KFM71028.1 - 0.13 12.4 2.5 0.52 10.5 2.5 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-CCHC_2 PF13696.6 KFM71028.1 - 0.29 11.0 4.4 1.3 8.9 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-H2C2_2 PF13465.6 KFM71029.1 - 2.1e-96 312.4 95.8 1.1e-10 41.4 0.6 12.2 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71029.1 - 7.4e-57 186.8 109.0 4.1e-06 27.0 0.8 12.2 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71029.1 - 3.8e-45 148.6 98.2 0.0001 22.8 0.6 12.2 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM71029.1 - 5e-24 83.8 92.4 0.00012 21.9 0.4 12.9 12 1 0 12 12 12 11 C2H2-type zinc finger zf-met PF12874.7 KFM71029.1 - 1.7e-14 53.6 87.0 0.00083 19.7 0.6 12.3 12 0 0 12 12 12 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM71029.1 - 1e-13 51.1 72.3 0.00075 19.7 0.1 12.3 11 1 1 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM71029.1 - 2.2e-05 24.1 67.3 0.0026 17.5 0.1 11.8 12 0 0 12 12 12 4 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM71029.1 - 0.00014 21.5 6.1 0.017 14.8 0.1 13.9 13 3 0 13 13 12 6 C2H2-type zinc-finger domain BolA PF01722.18 KFM71029.1 - 0.00035 20.8 17.3 16 5.8 0.0 6.8 3 2 3 6 6 6 0 BolA-like protein zf-C2HC_2 PF13913.6 KFM71029.1 - 0.0096 15.8 0.1 0.0096 15.8 0.1 10.8 12 0 0 12 12 11 3 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM71029.1 - 0.04 14.6 51.2 0.52 11.1 1.9 6.1 2 1 4 6 6 6 0 zinc-ribbon family Complex1_49kDa PF00346.19 KFM71029.1 - 0.13 11.3 0.6 1.9 7.5 0.0 2.6 1 1 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Baculo_IE-1 PF05290.11 KFM71029.1 - 0.14 12.1 40.2 4 7.4 0.8 8.1 1 1 3 5 5 5 0 Baculovirus immediate-early protein (IE-0) Scramblase PF03803.15 KFM71029.1 - 0.2 10.9 10.0 0.49 9.7 1.1 3.4 2 1 1 3 3 3 0 Scramblase zf-C2H2_3rep PF18868.1 KFM71029.1 - 0.56 10.9 43.5 6 7.6 0.1 8.7 2 2 5 7 7 7 0 Zinc finger C2H2-type, 3 repeats GAGA PF09237.11 KFM71029.1 - 1.2 9.0 21.9 4.2 7.2 0.1 5.9 3 2 3 6 6 6 0 GAGA factor Zn-ribbon_8 PF09723.10 KFM71029.1 - 3.2 8.0 54.8 1.5 9.0 3.7 8.4 5 2 3 8 8 8 0 Zinc ribbon domain C1_4 PF07975.12 KFM71029.1 - 3.3 8.0 65.7 0.18 12.0 4.7 8.0 3 2 7 10 10 10 0 TFIIH C1-like domain Adaptin_N PF01602.20 KFM71030.1 - 1.8e-56 191.8 0.6 2.5e-56 191.4 0.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KFM71030.1 - 2.8e-33 114.5 2.8 5.3e-33 113.6 2.8 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF5578 PF17741.1 KFM71030.1 - 0.023 14.1 0.2 0.047 13.1 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5578) Cnd1 PF12717.7 KFM71030.1 - 0.06 13.4 0.9 0.19 11.8 0.7 1.7 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 fn3 PF00041.21 KFM71032.1 - 2.5e-12 46.9 0.4 1.8e-10 41.0 0.1 2.1 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM71032.1 - 0.038 14.5 0.2 0.051 14.2 0.2 1.4 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KFM71033.1 - 1.8e-06 28.2 0.1 1.8e-06 28.2 0.1 1.0 1 0 0 1 1 1 1 Fibronectin type III domain zf-C4 PF00105.18 KFM71034.1 - 2.9e-31 107.7 12.4 2.9e-31 107.7 12.4 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFM71034.1 - 3.5e-25 88.8 0.5 5.6e-25 88.1 0.5 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ins134_P3_kin PF05770.11 KFM71035.1 - 2.8e-35 121.7 0.0 1.4e-34 119.4 0.0 1.8 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 KFM71035.1 - 6.9e-26 90.5 0.0 1.4e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain DUF726 PF05277.12 KFM71036.1 - 8.4e-37 126.9 2.6 9.5e-37 126.7 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Phage_holin_3_6 PF07332.11 KFM71036.1 - 0.049 13.7 6.2 0.071 13.1 6.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RseC_MucC PF04246.12 KFM71036.1 - 0.33 10.9 1.0 0.48 10.4 1.0 1.4 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC TraT PF05818.12 KFM71036.1 - 0.85 9.3 6.4 1.1 8.9 6.4 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF726 PF05277.12 KFM71037.1 - 1.7e-35 122.6 0.0 2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Di19_C PF14571.6 KFM71037.1 - 0.032 14.8 1.3 0.07 13.7 1.3 1.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal DUF4332 PF14229.6 KFM71037.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DDE_3 PF13358.6 KFM71038.1 - 5.8e-15 55.3 0.0 2.4e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71038.1 - 0.015 15.5 0.6 0.025 14.8 0.6 1.4 1 0 0 1 1 1 0 Transposase adh_short PF00106.25 KFM71039.1 - 2.1e-16 60.0 0.0 2.7e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM71039.1 - 2.9e-08 33.6 0.0 4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM71039.1 - 4.5e-05 23.4 0.1 7.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM71039.1 - 0.0025 17.3 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KFM71039.1 - 0.0068 17.0 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KFM71039.1 - 0.0079 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KFM71039.1 - 0.049 13.5 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KFM71039.1 - 0.055 13.1 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 KFM71039.1 - 0.068 13.0 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 KFM71039.1 - 0.072 12.4 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFM71039.1 - 0.086 13.1 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 KFM71040.1 - 7.6e-20 71.2 0.2 9.7e-20 70.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM71040.1 - 6.7e-11 42.2 0.0 8.3e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HTH_Tnp_Tc3_2 PF01498.18 KFM71041.1 - 9.6e-16 57.8 6.5 1.6e-15 57.1 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71041.1 - 2.4e-12 46.8 0.0 5.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71041.1 - 0.00079 20.0 1.5 0.00079 20.0 1.5 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71041.1 - 0.0027 17.4 0.1 0.064 13.1 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71041.1 - 0.017 15.2 0.1 0.051 13.7 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71041.1 - 0.027 14.5 2.1 0.034 14.2 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM71041.1 - 0.029 14.2 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase HTH_Tnp_Tc3_2 PF01498.18 KFM71042.1 - 1.6e-17 63.5 1.2 3.6e-17 62.4 1.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71042.1 - 6.9e-14 51.8 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71042.1 - 3.4e-05 24.4 8.0 4.9e-05 23.9 1.8 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_3 PF01381.22 KFM71042.1 - 0.0023 17.9 1.3 0.053 13.6 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 KFM71042.1 - 0.011 15.9 1.6 0.24 11.6 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 KFM71042.1 - 0.016 15.1 0.4 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_23 PF13384.6 KFM71042.1 - 0.035 13.9 1.7 0.72 9.7 0.1 2.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM71042.1 - 0.065 13.2 2.1 0.17 11.9 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM71042.1 - 0.14 11.7 1.9 1.7 8.3 0.0 2.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding Y_phosphatase PF00102.27 KFM71044.1 - 1.5e-81 273.4 0.4 2.9e-81 272.5 0.4 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 KFM71044.1 - 1.3e-65 217.7 19.6 3.7e-13 49.6 0.1 9.3 9 0 0 9 9 9 8 Fibronectin type III domain Interfer-bind PF09294.10 KFM71044.1 - 7.9e-10 39.0 0.1 2.7 8.4 0.0 7.1 7 0 0 7 7 7 1 Interferon-alpha/beta receptor, fibronectin type III PTP_tm PF18861.1 KFM71044.1 - 3.2e-08 33.8 2.8 7e-07 29.4 2.8 2.6 1 1 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Pur_ac_phosph_N PF16656.5 KFM71044.1 - 3.5e-07 30.7 14.0 1.6 9.3 0.1 7.3 7 2 1 8 8 7 4 Purple acid Phosphatase, N-terminal domain DUF4249 PF14054.6 KFM71044.1 - 1.2e-06 28.4 12.9 0.00036 20.3 1.4 4.0 3 2 2 5 5 5 3 Domain of unknown function (DUF4249) DSPc PF00782.20 KFM71044.1 - 0.0003 20.6 0.0 0.00081 19.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2369 PF10179.9 KFM71044.1 - 0.00099 19.4 0.7 59 4.1 0.0 6.1 6 0 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) CBM_4_9 PF02018.17 KFM71044.1 - 0.015 15.6 0.4 1.6 9.0 0.0 4.2 6 0 0 6 6 6 0 Carbohydrate binding domain RAMP PF04901.13 KFM71044.1 - 0.11 12.5 0.5 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Receptor activity modifying family SKG6 PF08693.10 KFM71044.1 - 1.8 8.0 5.8 3.2 7.2 5.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM71045.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71045.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71045.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71045.1 - 0.0024 17.6 0.6 0.0072 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71045.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM71047.1 - 1.6e-12 47.4 0.0 2.2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RhoGAP PF00620.27 KFM71048.1 - 0.0091 15.8 1.8 0.017 14.9 0.2 2.3 2 0 0 2 2 2 1 RhoGAP domain Neur_chan_memb PF02932.16 KFM71049.1 - 0.00084 19.5 0.2 0.00086 19.4 0.2 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 KFM71050.1 - 2.1e-24 86.9 0.7 2.2e-24 86.8 0.7 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PET117 PF15786.5 KFM71050.1 - 0.24 11.7 0.5 0.53 10.6 0.4 1.6 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Neur_chan_LBD PF02931.23 KFM71051.1 - 1e-08 34.9 0.1 1.1e-08 34.8 0.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFM71052.1 - 4.9e-11 42.5 0.0 5.2e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM71054.1 - 2.2e-17 63.0 2.4 6.1e-16 58.4 2.2 2.7 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM71054.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71054.1 - 1.2e-07 31.4 2.1 2.3e-07 30.4 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71054.1 - 0.00086 19.0 0.7 0.0026 17.5 0.7 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71054.1 - 1.3 9.7 16.2 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71056.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71056.1 - 8.8e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Amidase_2 PF01510.25 KFM71057.1 - 2.4e-13 50.6 1.8 2.5e-13 50.6 0.7 1.5 2 0 0 2 2 2 1 N-acetylmuramoyl-L-alanine amidase Ninjurin PF04923.12 KFM71058.1 - 2.6e-34 117.2 3.0 3.2e-34 116.9 3.0 1.1 1 0 0 1 1 1 1 Ninjurin DUF2694 PF10904.8 KFM71058.1 - 0.11 12.6 0.0 7.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2694) Ninjurin PF04923.12 KFM71059.1 - 3.3e-21 75.2 1.4 3.9e-21 74.9 1.4 1.1 1 0 0 1 1 1 1 Ninjurin TBK1_ULD PF18396.1 KFM71063.1 - 9.8e-11 41.4 0.6 1.1e-10 41.2 0.6 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain ubiquitin PF00240.23 KFM71063.1 - 0.0025 17.5 0.3 0.0032 17.2 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family TBK1_CCD1 PF18394.1 KFM71065.1 - 1.5e-17 64.0 6.0 1.5e-17 64.0 6.0 1.9 1 1 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 DUF3450 PF11932.8 KFM71065.1 - 0.15 11.3 7.0 0.34 10.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) LOH1CR12 PF10158.9 KFM71065.1 - 0.77 9.8 5.0 2.5 8.1 0.4 2.8 1 1 1 3 3 3 0 Tumour suppressor protein Pkinase PF00069.25 KFM71066.1 - 1.9e-48 165.1 0.0 2.7e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM71066.1 - 1.1e-33 116.7 0.0 1.7e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_ULD PF18396.1 KFM71066.1 - 6.8e-17 61.2 2.7 2.4e-15 56.2 1.5 2.3 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain RIO1 PF01163.22 KFM71066.1 - 0.00011 21.8 1.2 0.03 13.9 0.9 2.6 1 1 1 2 2 2 2 RIO1 family TBK1_CCD1 PF18394.1 KFM71066.1 - 0.00029 20.5 0.1 0.0006 19.5 0.1 1.5 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Pkinase_fungal PF17667.1 KFM71066.1 - 0.0019 17.1 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase ubiquitin PF00240.23 KFM71066.1 - 0.0028 17.3 0.2 0.0075 16.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin family Kinase-like PF14531.6 KFM71066.1 - 0.011 15.0 0.0 0.059 12.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Rad60-SLD PF11976.8 KFM71066.1 - 0.054 13.3 0.9 0.16 11.8 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like APH PF01636.23 KFM71066.1 - 0.072 13.0 0.0 1.2 9.0 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM71066.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.19 KFM71067.1 - 2.1e-59 201.2 0.0 4e-58 197.0 0.0 1.9 1 1 0 1 1 1 1 Actin DEAD PF00270.29 KFM71068.1 - 4.2e-12 46.2 0.0 5.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM71069.1 - 7.6e-28 97.1 0.0 1.5e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM71069.1 - 3.4e-22 79.1 0.0 6.2e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Acyl-thio_N PF12590.8 KFM71073.1 - 0.097 13.2 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 Acyl-ATP thioesterase HTH_Tnp_Tc3_2 PF01498.18 KFM71074.1 - 4.6e-16 58.8 3.5 6e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71074.1 - 3.4e-11 43.1 0.0 6.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71074.1 - 2.2e-07 30.5 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71074.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71074.1 - 2 9.1 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM71075.1 - 7.1e-65 219.6 0.1 8.5e-65 219.3 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Fasciclin PF02469.22 KFM71076.1 - 6e-113 372.4 0.0 3.9e-26 91.8 0.0 6.2 6 0 0 6 6 6 6 Fasciclin domain GRP PF07172.11 KFM71078.1 - 7.1 7.4 12.3 17 6.2 12.3 1.6 1 0 0 1 1 1 0 Glycine rich protein family NtCtMGAM_N PF16863.5 KFM71079.1 - 0.011 16.0 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase DUF4968 PF16338.5 KFM71079.1 - 0.018 15.3 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) Glyco_hydro_31 PF01055.26 KFM71080.1 - 2.7e-149 498.1 6.0 3.3e-149 497.8 6.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFM71080.1 - 4.8e-10 39.6 0.2 4.8e-08 33.2 0.0 2.8 2 1 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KFM71080.1 - 1.4e-06 28.5 0.0 3.7e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Peptidase_C2 PF00648.21 KFM71081.1 - 1.1e-124 415.3 0.0 1.6e-124 414.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFM71081.1 - 5e-52 175.9 0.0 9.4e-52 175.0 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 KFM71081.1 - 4.6e-12 44.6 0.5 0.00069 19.0 0.0 4.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFM71081.1 - 3.1e-09 36.0 0.2 0.0022 17.8 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFM71081.1 - 2.1e-07 30.6 8.2 1.4e-05 24.9 1.0 4.3 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_7 PF13499.6 KFM71081.1 - 6.7e-06 26.5 8.1 0.28 11.7 0.1 4.7 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM71081.1 - 2.5e-05 23.6 0.0 0.13 11.8 0.0 3.1 2 0 0 2 2 2 2 EF hand THAP PF05485.12 KFM71083.1 - 0.00027 21.8 0.1 0.00038 21.3 0.1 1.3 1 1 0 1 1 1 1 THAP domain Pro_racemase PF05544.11 KFM71084.1 - 1.5e-99 333.2 0.0 1.7e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Proline racemase DAP_epimerase PF01678.19 KFM71084.1 - 0.025 14.8 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Diaminopimelate epimerase DUF4566 PF15130.6 KFM71085.1 - 0.14 11.5 0.1 0.15 11.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) HTH_Tnp_Tc3_2 PF01498.18 KFM71086.1 - 7.4e-12 45.3 0.1 1.7e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71086.1 - 1.2e-09 38.1 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 KFM71086.1 - 0.0088 16.2 0.5 0.41 10.8 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM71086.1 - 0.089 12.2 1.7 2.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 KFM71086.1 - 2.2 9.0 9.0 0.68 10.6 0.2 3.4 3 1 1 4 4 4 0 Homeodomain-like domain DDE_3 PF13358.6 KFM71087.1 - 5.7e-16 58.6 0.1 6.1e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71087.1 - 7.9e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71087.1 - 0.001 19.7 1.7 0.001 19.7 1.7 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71087.1 - 0.0019 17.9 0.0 0.084 12.7 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71087.1 - 0.0079 16.3 0.2 0.062 13.4 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM71087.1 - 0.026 14.5 2.0 0.037 14.1 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM71087.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase CPG4 PF15481.6 KFM71088.1 - 0.00041 20.9 0.5 0.00053 20.5 0.5 1.1 1 0 0 1 1 1 1 Chondroitin proteoglycan 4 DUF1397 PF07165.11 KFM71088.1 - 0.0082 15.6 0.4 0.011 15.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1397) zf-C3HC4_3 PF13920.6 KFM71089.1 - 2.7e-09 36.8 14.2 2.7e-09 36.8 14.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM71089.1 - 1.6e-07 31.5 16.2 1.6e-07 31.5 16.2 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM71089.1 - 8.5e-07 28.7 16.8 8.5e-07 28.7 16.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM71089.1 - 9.3e-07 28.8 10.1 2.5e-06 27.4 7.8 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM71089.1 - 1.9e-06 27.6 18.0 1.9e-06 27.6 18.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM71089.1 - 6.9e-06 25.8 12.7 6.9e-06 25.8 12.7 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFM71089.1 - 8.8e-06 25.9 13.4 2.6e-05 24.4 13.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM71089.1 - 1.5e-05 24.9 16.8 1.5e-05 24.9 16.8 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM71089.1 - 4.6e-05 23.5 10.9 4.6e-05 23.5 10.9 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-CCHC PF00098.23 KFM71089.1 - 5.4e-05 23.1 3.2 5.4e-05 23.1 3.2 2.1 2 0 0 2 2 2 1 Zinc knuckle Granin PF01271.17 KFM71089.1 - 0.00038 19.5 2.5 0.00066 18.7 2.5 1.3 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) zf-ANAPC11 PF12861.7 KFM71089.1 - 0.0012 18.9 6.0 0.0025 17.8 6.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PRP38_assoc PF12871.7 KFM71089.1 - 0.0023 18.5 5.5 0.0037 17.8 5.5 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-CCHC_5 PF14787.6 KFM71089.1 - 0.005 16.5 4.0 0.005 16.5 4.0 1.8 2 0 0 2 2 1 1 GAG-polyprotein viral zinc-finger zf-RING_10 PF16685.5 KFM71089.1 - 0.0067 16.5 10.9 0.013 15.7 10.9 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KFM71089.1 - 0.033 14.4 0.3 0.073 13.2 0.0 1.7 2 0 0 2 2 1 0 U-box domain zf-RING_6 PF14835.6 KFM71089.1 - 0.035 14.0 5.2 0.083 12.8 5.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RHD3 PF05879.12 KFM71089.1 - 0.33 9.0 7.3 0.45 8.6 7.3 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF2325 PF10087.9 KFM71089.1 - 0.79 9.9 4.2 2.3 8.4 4.2 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Corona_nucleoca PF00937.18 KFM71089.1 - 1.2 8.1 5.9 0.13 11.3 1.5 1.5 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DZR PF12773.7 KFM71089.1 - 2.5 8.2 12.7 18 5.5 10.0 2.8 2 1 0 2 2 2 0 Double zinc ribbon DDE_Tnp_1_7 PF13843.6 KFM71090.1 - 2.5e-63 214.5 3.8 3e-63 214.2 3.8 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM71090.1 - 0.07 12.8 0.1 0.14 11.8 0.0 1.5 1 1 1 2 2 2 0 Transposase DDE domain Prok-TraM PF09228.10 KFM71091.1 - 0.07 13.5 0.6 0.17 12.3 0.2 1.9 2 1 1 3 3 3 0 Prokaryotic Transcriptional repressor TraM DNA_pol_phi PF04931.13 KFM71091.1 - 0.085 11.0 7.8 0.091 10.8 7.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KFM71091.1 - 1.4 7.1 8.1 1.5 7.0 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Acyl-CoA_dh_1 PF00441.24 KFM71092.1 - 1.8e-43 148.4 0.2 2.4e-43 147.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM71092.1 - 2.8e-27 95.6 0.0 5.1e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM71092.1 - 1e-20 73.7 0.0 1.7e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM71092.1 - 2.5e-15 57.0 0.0 3.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFM71092.1 - 0.055 13.1 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Metallophos PF00149.28 KFM71094.1 - 1.6e-25 90.8 1.1 2.7e-25 90.1 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KFM71094.1 - 7.2e-23 81.2 0.1 3.1e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KFM71094.1 - 1.1e-17 64.4 0.0 2.2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 KFM71094.1 - 0.0021 18.3 0.0 0.011 15.9 0.1 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Zona_pellucida PF00100.23 KFM71095.1 - 0.00077 19.3 0.0 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 Zona pellucida-like domain Insulin_TMD PF17870.1 KFM71095.1 - 0.2 11.8 0.2 0.5 10.5 0.2 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment FH2 PF02181.23 KFM71096.1 - 2.7e-87 293.3 10.8 2.7e-87 293.3 10.8 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain IBB PF01749.20 KFM71096.1 - 0.0079 16.6 2.0 0.0079 16.6 2.0 4.3 3 0 0 3 3 3 1 Importin beta binding domain DUF4007 PF13182.6 KFM71096.1 - 0.11 11.6 2.0 0.28 10.3 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) Mt_ATP-synt_D PF05873.12 KFM71096.1 - 0.46 10.3 6.7 1.6 8.5 1.2 3.5 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Lectin_N PF03954.14 KFM71096.1 - 0.62 9.8 8.3 0.34 10.7 3.7 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.12 KFM71096.1 - 1.4 9.0 10.7 0.081 13.0 3.8 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5344 PF17279.2 KFM71096.1 - 4.2 8.0 16.1 3.1 8.4 6.5 4.5 4 0 0 4 4 4 0 Family of unknown function (DUF5344) Osmo_CC PF08946.10 KFM71096.1 - 7.6 6.9 12.1 0.073 13.3 0.7 3.1 3 0 0 3 3 3 0 Osmosensory transporter coiled coil SNF2_N PF00176.23 KFM71097.1 - 1.8e-69 234.1 2.9 1.8e-69 234.1 2.9 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM71097.1 - 1.7e-20 73.4 0.4 1.6e-19 70.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 KFM71097.1 - 1.9e-19 69.8 11.2 1.9e-19 69.8 11.2 4.3 2 1 1 3 3 3 1 HSA gag-asp_proteas PF13975.6 KFM71098.1 - 2.5e-13 50.4 0.0 7.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM71098.1 - 6.8e-11 42.7 0.0 1.4e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KFM71098.1 - 0.00089 19.1 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM71098.1 - 0.028 14.7 0.1 0.11 12.8 0.1 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease Spuma_A9PTase PF03539.14 KFM71098.1 - 0.035 14.2 0.1 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) UPF0086 PF01868.16 KFM71098.1 - 0.067 13.1 0.5 0.2 11.6 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function UPF0086 DUF3794 PF12673.7 KFM71098.1 - 0.07 13.4 0.2 0.2 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3794) MLVIN_C PF18697.1 KFM71099.1 - 0.0015 18.6 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain CBF PF03914.17 KFM71101.1 - 3.2e-08 33.8 0.0 3.5e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 CBF/Mak21 family SM-ATX PF14438.6 KFM71103.1 - 2.9e-19 69.0 0.0 7.6e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 KFM71103.1 - 1.1e-13 51.5 2.1 1.1e-13 51.5 2.1 2.7 2 1 1 3 3 3 1 LsmAD domain PAM2 PF07145.15 KFM71103.1 - 1.3e-07 30.8 7.2 0.0017 17.9 2.0 2.7 1 1 1 2 2 2 2 Ataxin-2 C-terminal region LSM PF01423.22 KFM71103.1 - 0.0063 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 LSM domain QRPTase_C PF01729.19 KFM71104.1 - 3.2e-55 186.5 0.0 4e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KFM71104.1 - 1.7e-18 66.5 0.0 5.4e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain zf-H2C2_2 PF13465.6 KFM71105.1 - 9.3e-19 66.9 32.8 2.5e-07 30.8 3.4 3.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71105.1 - 1.8e-07 31.2 38.2 7.7e-05 22.9 3.8 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM71105.1 - 0.00065 19.4 45.4 0.001 18.8 5.3 4.8 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM71105.1 - 0.00065 20.3 33.2 0.0039 17.9 1.7 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger C1_1 PF00130.22 KFM71105.1 - 0.023 14.6 3.5 0.023 14.6 3.5 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrsD PF12013.8 KFM71105.1 - 0.03 14.8 14.6 0.064 13.7 1.8 3.1 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 KFM71105.1 - 0.037 14.3 9.6 0.037 14.3 9.6 4.2 4 3 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM71105.1 - 0.046 13.6 3.0 0.13 12.2 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM71105.1 - 0.062 13.1 1.0 0.062 13.1 1.0 2.1 1 1 1 2 2 2 0 GAGA factor DUF629 PF04780.12 KFM71105.1 - 0.37 9.3 10.0 0.034 12.7 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF629) Fer4_8 PF13183.6 KFM71105.1 - 0.53 10.8 15.5 3.1 8.3 0.9 3.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain zf-C2H2_2 PF12756.7 KFM71105.1 - 1.1 9.6 16.9 3.4 8.0 9.3 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.6 KFM71105.1 - 5.3 7.2 24.2 8 6.6 2.5 3.2 1 1 2 3 3 3 0 Zinc-finger Actin_micro PF17003.5 KFM71105.1 - 5.6 6.0 14.3 0.58 9.3 7.4 2.3 1 1 1 2 2 2 0 Putative actin-like family MMR_HSR1_Xtn PF16897.5 KFM71106.1 - 1.3e-41 140.9 1.4 2.4e-41 140.0 0.9 1.7 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KFM71106.1 - 1.4e-23 82.7 0.1 2.6e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KFM71106.1 - 9.4e-21 74.0 0.0 2.7e-20 72.5 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM71106.1 - 5.8e-11 42.2 0.2 5.1e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KFM71106.1 - 0.00085 18.4 0.5 0.026 13.5 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KFM71106.1 - 0.0018 18.4 0.2 0.95 9.5 0.2 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KFM71106.1 - 0.027 14.0 0.1 8.6 5.8 0.0 3.5 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM71106.1 - 0.084 12.8 0.5 1.5 8.7 0.0 2.7 2 1 1 3 3 3 0 RsgA GTPase Mg_chelatase PF01078.21 KFM71106.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PigN PF04987.14 KFM71107.1 - 1.4e-19 70.4 9.7 1.4e-19 70.4 9.7 1.3 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) PigN PF04987.14 KFM71108.1 - 3.1e-05 23.1 0.1 3.3e-05 23.0 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KFM71109.1 - 1.7e-05 24.6 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFM71109.1 - 0.00055 19.4 0.0 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KFM71109.1 - 0.072 12.4 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily HisKA PF00512.25 KFM71109.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Phosphodiest PF01663.22 KFM71110.1 - 0.0012 18.6 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase zf-C2H2 PF00096.26 KFM71111.1 - 2.2e-07 30.9 13.7 0.0073 16.7 0.2 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KFM71111.1 - 0.00023 21.8 2.8 0.00023 21.8 2.8 1.8 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 KFM71111.1 - 0.00082 20.0 10.1 0.071 14.0 0.2 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_12 PF18658.1 KFM71111.1 - 0.13 11.9 3.5 0.12 12.0 1.1 2.1 1 1 1 2 2 2 0 Zinc-finger C2H2-type RelA_SpoT PF04607.17 KFM71111.1 - 0.2 12.0 1.4 3.3 8.0 0.3 2.2 1 1 1 2 2 2 0 Region found in RelA / SpoT proteins DUF629 PF04780.12 KFM71111.1 - 0.68 8.4 8.3 0.52 8.8 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.8 KFM71111.1 - 1.5 9.2 9.2 0.66 10.3 1.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Exonuc_VIII PF06630.11 KFM71112.1 - 0.036 13.9 0.0 0.036 13.9 0.0 1.0 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII p450 PF00067.22 KFM71112.1 - 0.16 10.7 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 DUF1295 PF06966.12 KFM71113.1 - 1.9e-13 50.5 0.5 2.2e-13 50.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4773 PF15998.5 KFM71114.1 - 2.5e-31 108.6 1.1 3.2e-31 108.3 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) GlyL_C PF12524.8 KFM71114.1 - 0.49 10.6 6.2 1.6 8.9 0.0 3.1 3 0 0 3 3 3 0 dsDNA virus glycoprotein L C terminal zf-H2C2_2 PF13465.6 KFM71115.1 - 1.1e-88 288.0 76.5 6.4e-09 35.8 0.8 13.1 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71115.1 - 1.6e-62 204.6 83.0 1.6e-06 28.3 0.3 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71115.1 - 5.5e-45 148.1 80.6 0.00034 21.2 1.2 11.5 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM71115.1 - 9.4e-36 121.2 75.7 0.00072 19.9 0.7 12.2 12 0 0 12 12 12 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM71115.1 - 8.1e-23 79.9 62.9 0.012 15.6 0.9 11.6 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM71115.1 - 1.6e-20 72.9 50.8 0.0074 16.6 0.2 12.0 11 1 1 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM71115.1 - 6.7e-19 67.3 47.5 0.013 15.2 0.2 11.6 11 0 0 11 11 11 7 C2H2-type zinc-finger domain GAGA PF09237.11 KFM71115.1 - 1.1e-10 41.1 22.1 0.00011 21.9 1.0 7.7 3 2 5 8 8 8 3 GAGA factor zf-C2H2_2 PF12756.7 KFM71115.1 - 3.6e-08 33.7 62.1 0.36 11.2 1.5 10.4 1 1 9 10 10 10 5 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFM71115.1 - 1.3e-07 31.8 7.0 0.11 12.8 0.0 6.2 2 2 4 6 6 6 1 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM71115.1 - 2e-07 30.9 35.8 0.69 10.0 0.0 10.7 8 1 3 11 11 11 4 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM71115.1 - 2.8e-07 30.4 29.5 0.41 10.7 0.5 7.4 3 3 3 6 6 6 3 Adenylate kinase, active site lid zf-DBF PF07535.12 KFM71115.1 - 9.9e-06 25.6 41.5 4.1 7.6 0.1 10.7 11 0 0 11 11 10 1 DBF zinc finger zf-C2HC_2 PF13913.6 KFM71115.1 - 1e-05 25.3 44.1 0.27 11.2 0.2 10.7 11 0 0 11 11 11 2 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM71115.1 - 6.7e-05 22.6 35.7 1.1 9.1 0.0 10.6 5 4 6 11 11 11 1 C2H2 type zinc-finger (1 copy) C1_1 PF00130.22 KFM71115.1 - 8e-05 22.4 51.1 1.1 9.2 4.3 9.3 5 3 4 9 9 9 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 KFM71115.1 - 0.00037 20.2 51.4 0.049 13.4 0.5 9.3 10 0 0 10 10 10 3 zinc-finger C2H2-type DUF2256 PF10013.9 KFM71115.1 - 0.00078 19.5 40.0 27 5.0 0.0 10.9 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 KFM71115.1 - 0.0012 18.3 42.8 2.6 7.7 0.1 10.7 11 0 0 11 11 11 2 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM71115.1 - 0.002 17.7 47.3 5.7 6.6 0.2 10.9 5 3 6 11 11 11 1 MYST family zinc finger domain zf-RRPl_C4 PF17026.5 KFM71115.1 - 0.0044 17.1 36.7 0.084 13.0 4.5 5.4 1 1 5 6 6 6 2 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 KFM71115.1 - 0.0049 16.9 37.7 0.68 10.1 0.4 7.5 5 3 2 7 7 7 3 Zinc ribbon domain GATase_2 PF00310.21 KFM71115.1 - 0.037 12.7 0.1 0.26 9.9 0.0 2.0 1 1 1 2 2 2 0 Glutamine amidotransferases class-II zinc_ribbon_15 PF17032.5 KFM71115.1 - 0.12 13.1 37.3 2.6 8.9 0.8 6.2 3 2 5 8 8 8 0 zinc-ribbon family DUF4825 PF16107.5 KFM71115.1 - 0.14 12.3 0.0 7.1 6.8 0.0 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4825) Prok-RING_1 PF14446.6 KFM71115.1 - 0.27 11.2 38.8 28 4.7 0.1 10.4 10 1 1 11 11 11 0 Prokaryotic RING finger family 1 HNH_5 PF14279.6 KFM71115.1 - 0.56 10.1 43.2 9.1 6.2 0.0 10.5 9 2 2 11 11 11 0 HNH endonuclease Zf_RING PF16744.5 KFM71115.1 - 0.65 10.2 48.0 1.9 8.7 0.3 10.3 2 2 5 8 8 8 0 KIAA1045 RING finger 7tm_1 PF00001.21 KFM71117.1 - 6.7e-31 107.6 11.8 9e-31 107.1 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM71117.1 - 9.5e-12 44.8 10.5 1.4e-11 44.3 10.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM71117.1 - 0.00011 21.9 20.9 0.00011 21.9 20.9 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 KFM71117.1 - 0.0057 16.2 17.5 0.014 14.9 17.5 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc Ig_3 PF13927.6 KFM71118.1 - 4.2e-41 139.4 3.9 1.5e-14 54.3 0.1 3.1 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM71118.1 - 1e-40 137.7 0.1 5.3e-13 48.9 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM71118.1 - 4.5e-28 97.4 1.5 6.4e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM71118.1 - 4.8e-20 71.5 0.5 3.7e-05 23.8 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM71118.1 - 6.5e-20 71.3 4.2 8.6e-10 38.8 0.1 4.9 4 1 0 4 4 4 4 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM71118.1 - 1.1e-08 35.2 0.0 0.17 12.2 0.0 4.3 3 1 0 3 3 3 3 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM71118.1 - 5.1e-08 33.2 0.3 0.018 15.4 0.0 4.5 3 2 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM71118.1 - 1.1e-07 31.8 0.0 0.04 14.0 0.0 3.1 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KFM71118.1 - 3.5e-05 23.8 0.5 0.017 15.1 0.1 3.3 3 1 0 3 3 3 1 CD47 immunoglobulin-like domain Ig_6 PF18452.1 KFM71118.1 - 0.00016 21.2 0.0 7.3 6.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFM71118.1 - 0.0065 16.2 1.9 5 7.0 0.0 3.7 3 1 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFM71118.1 - 0.023 14.7 0.0 7.3 6.7 0.0 3.6 3 1 0 3 3 3 0 C17orf99 Ig domain Apc13p PF05839.11 KFM71119.1 - 2.9e-13 49.8 0.3 4.2e-13 49.3 0.3 1.2 1 0 0 1 1 1 1 Apc13p protein DDE_3 PF13358.6 KFM71121.1 - 4e-08 33.1 0.0 6.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 KFM71122.1 - 2.8e-34 118.6 0.1 6.1e-34 117.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM71122.1 - 5.8e-06 26.1 0.3 1.9e-05 24.5 0.3 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HAD_2 PF13419.6 KFM71122.1 - 0.52 10.4 2.9 1.3 9.1 2.4 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Glyco_tran_28_C PF04101.16 KFM71122.1 - 1.2 9.1 3.2 0.61 10.0 0.2 2.0 2 1 1 3 3 3 0 Glycosyltransferase family 28 C-terminal domain DDRGK PF09756.9 KFM71123.1 - 0.55 9.8 28.1 0.85 9.2 27.6 1.5 1 1 0 1 1 1 0 DDRGK domain Paramyxo_ncap PF00973.19 KFM71123.1 - 5.2 5.9 7.9 6.7 5.5 7.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC37_N PF03234.14 KFM71123.1 - 9 7.2 19.0 1.9 9.4 4.6 2.6 1 1 2 3 3 3 0 Cdc37 N terminal kinase binding DUF5641 PF18701.1 KFM71124.1 - 4.5e-23 81.2 0.0 1.2e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1759 PF03564.15 KFM71124.1 - 6.6e-22 78.0 0.2 2.7e-21 76.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM71124.1 - 4.6e-10 39.5 0.0 9.8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 KFM71124.1 - 0.017 15.8 0.0 0.14 12.8 0.0 2.5 3 0 0 3 3 3 0 Aspartyl protease eIF3g PF12353.8 KFM71124.1 - 0.16 12.4 2.6 2 8.8 0.5 3.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Ank PF00023.30 KFM71125.1 - 2.1e-07 31.1 0.0 2.1e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KFM71125.1 - 1.1e-06 29.1 0.0 1.1e-06 29.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM71125.1 - 1.7e-06 27.9 0.0 1.9e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 KFM71125.1 - 1.1e-05 25.6 0.0 1.2e-05 25.5 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM71125.1 - 0.00069 20.1 0.0 0.00085 19.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) UPA_2 PF17809.1 KFM71126.1 - 2e-54 182.9 0.4 1.1e-53 180.6 0.1 2.3 2 0 0 2 2 2 1 UPA domain ZU5 PF00791.20 KFM71126.1 - 4.8e-34 116.6 0.9 2.8e-26 91.7 0.0 2.8 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 KFM71126.1 - 5.4e-16 58.5 2.3 1.3e-15 57.3 2.3 1.7 1 0 0 1 1 1 1 Death domain Ank_5 PF13857.6 KFM71126.1 - 1.8e-12 47.3 0.1 4.7e-12 45.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM71126.1 - 1.6e-09 38.2 0.1 6.8e-09 36.2 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM71126.1 - 4.1e-08 33.6 0.0 3.2e-05 24.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM71126.1 - 1.2e-06 28.7 0.1 7.4e-05 23.0 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KFM71126.1 - 2.2e-05 24.5 0.0 0.00064 20.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Topoisom_I_N PF02919.15 KFM71127.1 - 0.0073 15.8 0.2 0.041 13.4 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Prefoldin PF02996.17 KFM71127.1 - 4.7 7.2 7.7 1.4 8.9 0.3 3.8 3 1 0 3 3 3 0 Prefoldin subunit FTA4 PF13093.6 KFM71128.1 - 0.0052 16.7 5.8 0.11 12.3 0.5 2.6 2 0 0 2 2 2 2 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 APG6_N PF17675.1 KFM71128.1 - 0.012 16.1 18.8 0.049 14.2 9.8 3.1 2 0 0 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 KFM71128.1 - 0.09 12.1 15.0 0.12 11.7 7.6 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PCRF PF03462.18 KFM71128.1 - 0.17 11.8 6.8 2.6 7.8 0.7 2.6 2 0 0 2 2 2 0 PCRF domain SKA2 PF16740.5 KFM71128.1 - 0.2 11.5 6.3 0.73 9.6 0.2 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DHR10 PF18595.1 KFM71128.1 - 1.2 9.2 14.7 0.3 11.2 6.8 2.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 KFM71128.1 - 1.9 9.0 5.9 36 4.8 0.1 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 KFM71128.1 - 2.3 8.7 6.2 5.5 7.5 1.1 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.6 KFM71128.1 - 3.6 7.9 10.9 0.84 9.9 5.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) FapA PF03961.13 KFM71128.1 - 6.5 5.2 7.3 11 4.5 1.5 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A YabA PF06156.13 KFM71128.1 - 8 7.2 10.5 21 5.8 3.7 2.9 2 0 0 2 2 2 0 Initiation control protein YabA DDE_3 PF13358.6 KFM71129.1 - 5e-16 58.8 0.1 5.5e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71129.1 - 6.8e-16 58.3 5.9 1.2e-15 57.4 5.9 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71129.1 - 0.00064 20.3 1.2 0.00064 20.3 1.2 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71129.1 - 0.0021 17.8 0.1 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71129.1 - 0.014 15.5 0.1 0.063 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71129.1 - 0.045 13.8 0.8 0.045 13.8 0.8 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM71130.1 - 2.9e-16 59.5 0.1 3.1e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71130.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Innexin PF00876.18 KFM71131.1 - 8.3e-94 314.7 13.2 9.4e-94 314.6 13.2 1.0 1 0 0 1 1 1 1 Innexin DUF4371 PF14291.6 KFM71132.1 - 3.3e-07 30.2 0.0 4.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KFM71132.1 - 0.00088 19.2 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) HTH_Tnp_Tc3_2 PF01498.18 KFM71133.1 - 5.8e-16 58.5 2.2 5.8e-16 58.5 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM71133.1 - 1.3e-13 51.0 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71133.1 - 1.6e-07 30.9 1.2 7.1e-07 28.9 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71133.1 - 0.0027 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71133.1 - 2.3 8.9 15.6 0.12 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71134.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71134.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71135.1 - 9e-17 61.1 1.2 1.9e-16 60.1 1.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71135.1 - 2.5e-14 53.3 0.0 4.1e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71135.1 - 0.00011 22.8 7.9 0.00026 21.5 0.9 3.1 3 0 0 3 3 3 1 Homeodomain-like domain LptD PF04453.14 KFM71135.1 - 0.073 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 LPS transport system D HTH_Tnp_Tc3_2 PF01498.18 KFM71136.1 - 2.2e-16 59.9 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71136.1 - 9.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 KFM71137.1 - 2.5e-31 108.9 0.2 3.2e-31 108.6 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Adap_comp_sub PF00928.21 KFM71138.1 - 8e-62 209.0 0.0 9.9e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFM71138.1 - 2e-09 37.5 0.0 3.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sod_Cu PF00080.20 KFM71141.1 - 3.5e-39 134.2 1.2 5.2e-39 133.6 1.2 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 KFM71141.1 - 2.7e-11 43.7 0.3 6.4e-11 42.5 0.3 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Myb_DNA-binding PF00249.31 KFM71142.1 - 5.9e-06 26.4 0.1 1.1e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain GATA PF00320.27 KFM71142.1 - 0.00079 19.0 5.1 0.00079 19.0 5.1 1.8 2 0 0 2 2 2 1 GATA zinc finger Myb_DNA-bind_7 PF15963.5 KFM71142.1 - 0.015 15.1 0.2 0.023 14.6 0.2 1.4 1 1 0 1 1 1 0 Myb DNA-binding like MTA_R1 PF17226.2 KFM71143.1 - 3.1e-29 101.0 2.6 6.1e-28 96.8 0.1 2.3 2 0 0 2 2 2 2 MTA R1 domain PH_6 PF15406.6 KFM71144.1 - 0.053 13.8 0.0 0.062 13.6 0.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain PhaP_Bmeg PF09602.10 KFM71145.1 - 0.044 13.7 0.7 0.055 13.4 0.7 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) KHA PF11834.8 KFM71145.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel ADH_N PF08240.12 KFM71146.1 - 7.9e-27 93.3 4.4 8.8e-27 93.1 2.8 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM71146.1 - 4.4e-22 78.4 0.7 6.9e-22 77.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFM71146.1 - 0.014 14.8 0.1 0.048 13.0 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFM71146.1 - 0.12 12.6 0.1 0.29 11.4 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KFM71146.1 - 0.15 11.6 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DDE_3 PF13358.6 KFM71147.1 - 9e-10 38.5 0.0 9.1e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease ADK PF00406.22 KFM71148.1 - 1.5e-06 28.4 0.1 1.7e-05 25.0 0.0 2.7 2 1 0 2 2 2 1 Adenylate kinase MARVEL PF01284.23 KFM71149.1 - 1.5e-20 73.7 17.6 1.9e-20 73.4 17.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF973 PF06157.11 KFM71149.1 - 0.03 13.4 4.6 0.043 12.9 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) EOS1 PF12326.8 KFM71149.1 - 0.044 13.7 1.7 0.076 12.9 0.4 1.9 1 1 1 2 2 2 0 N-glycosylation protein Nudc_N PF14050.6 KFM71150.1 - 1.9e-17 63.0 0.1 3.1e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 KFM71150.1 - 1.4e-13 51.7 0.4 2.2e-13 51.0 0.4 1.4 1 0 0 1 1 1 1 CS domain Thioredoxin_2 PF13098.6 KFM71150.1 - 0.028 14.9 0.3 0.085 13.3 0.1 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain Evr1_Alr PF04777.13 KFM71151.1 - 9.6e-15 54.9 2.7 1.6e-14 54.2 0.2 2.0 2 0 0 2 2 2 1 Erv1 / Alr family zf-H2C2_2 PF13465.6 KFM71152.1 - 7.5e-45 149.4 23.7 5.4e-11 42.4 0.6 5.1 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71152.1 - 1.4e-29 100.9 29.6 3.2e-06 27.3 0.3 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71152.1 - 3.2e-18 64.8 30.7 0.00042 20.9 0.3 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.7 KFM71152.1 - 2e-17 62.9 28.4 9.4e-05 22.7 0.4 6.0 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM71152.1 - 1.2e-12 47.4 12.6 0.0025 17.5 0.1 5.1 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM71152.1 - 8.7e-09 35.4 16.8 0.16 12.3 0.2 5.5 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM71152.1 - 6.9e-07 29.1 30.5 0.28 11.2 0.4 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-DBF PF07535.12 KFM71152.1 - 2.4e-06 27.5 13.8 1.5 9.0 0.1 5.4 5 0 0 5 5 5 1 DBF zinc finger zf-C2H2_11 PF16622.5 KFM71152.1 - 4.1e-06 26.5 16.0 0.26 11.1 0.3 5.2 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM71152.1 - 9.1e-05 22.4 14.6 1.3 9.1 0.1 5.0 4 1 1 5 5 5 2 Sec23/Sec24 zinc finger zf-CHCC PF10276.9 KFM71152.1 - 9.5e-05 22.4 1.6 51 4.0 0.0 5.0 5 0 0 5 5 5 0 Zinc-finger domain DUF2256 PF10013.9 KFM71152.1 - 0.00015 21.8 10.6 2.3 8.4 0.1 5.1 5 0 0 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM71152.1 - 0.00029 20.7 11.5 0.051 13.6 0.8 3.7 1 1 4 5 5 5 4 Adenylate kinase, active site lid DUF2757 PF10955.8 KFM71152.1 - 0.00035 20.8 10.7 1.2 9.4 0.2 4.9 5 0 0 5 5 5 1 Protein of unknown function (DUF2757) BolA PF01722.18 KFM71152.1 - 0.00049 20.3 1.4 2.1 8.7 0.1 3.4 1 1 2 3 3 3 2 BolA-like protein zf-Di19 PF05605.12 KFM71152.1 - 0.0013 19.0 26.9 0.61 10.4 1.1 4.9 1 1 2 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.22 KFM71152.1 - 0.0015 18.4 18.0 0.78 9.7 2.2 4.8 1 1 3 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KFM71152.1 - 0.0053 16.7 13.3 3.3 7.7 0.1 5.0 5 0 0 5 5 5 1 Prokaryotic RING finger family 1 zinc_ribbon_15 PF17032.5 KFM71152.1 - 0.024 15.4 12.9 1.2 9.9 1.0 2.9 1 1 1 2 2 2 0 zinc-ribbon family Tox-HNH-HHH PF15637.6 KFM71152.1 - 0.034 14.3 0.4 4.3 7.5 0.1 2.7 1 1 2 3 3 3 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2HC_2 PF13913.6 KFM71152.1 - 0.042 13.7 18.2 0.77 9.7 0.1 5.5 6 0 0 6 6 5 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM71152.1 - 0.047 13.3 17.4 1.9 8.1 0.2 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger PqqA PF08042.11 KFM71152.1 - 0.068 13.2 0.7 2.1e+02 2.2 0.0 4.5 5 0 0 5 5 5 0 PqqA family zf-C2H2_9 PF16293.5 KFM71152.1 - 0.084 12.7 16.8 0.53 10.2 0.2 4.5 3 1 3 6 6 5 0 C2H2 type zinc-finger (1 copy) YyzF PF14116.6 KFM71152.1 - 0.088 12.8 11.8 23 5.1 0.1 4.9 4 1 1 5 5 5 0 YyzF-like protein zf-Dof PF02701.15 KFM71152.1 - 0.12 12.6 9.9 23 5.2 0.0 4.6 1 1 4 5 5 5 0 Dof domain, zinc finger Ntox34 PF15606.6 KFM71152.1 - 0.13 12.4 0.6 1.9 8.7 0.1 2.8 2 1 1 3 3 2 0 Bacterial toxin 34 zf-RRPl_C4 PF17026.5 KFM71152.1 - 0.24 11.5 11.0 10 6.2 11.0 2.5 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type FYVE PF01363.21 KFM71152.1 - 0.26 11.5 19.1 12 6.1 7.1 3.3 1 1 1 2 2 2 0 FYVE zinc finger zf-HIT PF04438.16 KFM71152.1 - 0.26 11.2 19.5 13 5.7 0.3 5.1 5 0 0 5 5 5 0 HIT zinc finger zf-FPG_IleRS PF06827.14 KFM71152.1 - 0.36 10.8 13.9 25 4.8 0.2 4.9 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS HNH_5 PF14279.6 KFM71152.1 - 0.44 10.5 16.2 15 5.6 3.7 4.7 3 2 0 3 3 3 0 HNH endonuclease zf-MYST PF17772.1 KFM71152.1 - 0.46 10.1 14.5 13 5.4 0.1 5.0 1 1 4 5 5 5 0 MYST family zinc finger domain XPA_N PF01286.18 KFM71152.1 - 0.73 9.9 15.3 29 4.8 0.2 4.9 5 0 0 5 5 5 0 XPA protein N-terminal Laminin_N PF00055.17 KFM71152.1 - 0.85 9.2 7.0 1 8.9 4.4 2.3 1 1 1 2 2 2 0 Laminin N-terminal (Domain VI) DUF4764 PF15961.5 KFM71152.1 - 1 7.9 10.9 0.95 8.1 1.4 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4764) Zn-ribbon_8 PF09723.10 KFM71152.1 - 1.5 9.0 13.8 6.9 6.9 1.0 3.7 1 1 4 5 5 5 0 Zinc ribbon domain DUF5330 PF17264.2 KFM71152.1 - 1.9 8.6 11.3 71 3.5 0.1 4.8 5 0 0 5 5 5 0 Family of unknown function (DUF5330) zf-C2H2_2 PF12756.7 KFM71152.1 - 2 8.8 20.0 2.3 8.6 8.5 3.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFM71152.1 - 3.5 7.5 14.1 4.6 7.1 0.0 4.3 1 1 4 5 5 5 0 GAGA factor zf-trcl PF13451.6 KFM71152.1 - 4 7.4 16.8 24 4.9 0.1 4.9 5 0 0 5 5 5 0 Probable zinc-ribbon domain zf-Paramyx-P PF13008.7 KFM71152.1 - 5.3 6.6 12.6 38 3.8 0.1 4.7 5 0 0 5 5 5 0 Zinc-binding domain of Paramyxoviridae V protein DEK_C PF08766.11 KFM71154.1 - 1e-06 28.6 1.6 1.4e-06 28.1 0.1 2.1 3 0 0 3 3 3 1 DEK C terminal domain Lzipper-MIP1 PF14389.6 KFM71156.1 - 0.12 12.7 0.4 0.12 12.7 0.4 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DEK_C PF08766.11 KFM71157.1 - 1.1e-07 31.6 0.0 3.1e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 DEK C terminal domain zf-H2C2_2 PF13465.6 KFM71158.1 - 3.4e-95 308.6 137.5 1.2e-07 31.8 0.1 18.0 18 0 0 18 18 18 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71158.1 - 9.3e-60 195.9 156.0 3.2e-05 24.1 3.1 16.8 17 0 0 17 17 17 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71158.1 - 4.4e-46 151.5 147.1 0.0039 17.9 0.3 16.4 17 0 0 17 17 16 15 C2H2-type zinc finger zf-met PF12874.7 KFM71158.1 - 1.2e-21 76.4 135.7 0.0006 20.1 2.6 17.0 17 0 0 17 17 17 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM71158.1 - 1.9e-16 59.6 125.0 0.0028 17.6 0.8 16.3 17 0 0 17 17 17 10 C2H2-type zinc finger GAGA PF09237.11 KFM71158.1 - 8.6e-08 31.9 41.4 0.33 10.8 0.2 10.2 3 2 6 11 11 11 5 GAGA factor zf-C2H2_jaz PF12171.8 KFM71158.1 - 1.1e-07 31.9 107.3 0.047 14.0 0.1 16.2 16 1 1 17 17 17 8 Zinc-finger double-stranded RNA-binding zf-RRPl_C4 PF17026.5 KFM71158.1 - 3.4e-05 23.9 78.1 1.2 9.3 0.8 7.8 1 1 7 8 8 8 6 Putative ribonucleoprotein zinc-finger pf C4 type zf-H2C2_5 PF13909.6 KFM71158.1 - 9.4e-05 22.1 111.5 0.063 13.1 0.4 16.1 17 0 0 17 17 16 10 C2H2-type zinc-finger domain DUF3396 PF11876.8 KFM71158.1 - 0.00013 21.5 0.0 0.56 9.6 0.0 3.9 4 1 1 5 5 5 1 Protein of unknown function (DUF3396) zf-C2H2_9 PF16293.5 KFM71158.1 - 0.00028 20.6 72.9 0.95 9.4 0.3 14.9 3 3 13 16 16 16 3 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFM71158.1 - 0.00055 19.6 102.4 0.082 12.7 1.4 15.4 16 0 0 16 16 16 8 zinc-finger C2H2-type Tox-HNH-HHH PF15637.6 KFM71158.1 - 0.00097 19.3 13.7 2.2 8.5 0.0 6.8 2 2 6 8 8 8 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif FYVE PF01363.21 KFM71158.1 - 0.017 15.2 89.7 0.041 14.0 12.5 8.1 2 1 4 6 6 5 0 FYVE zinc finger zf-DBF PF07535.12 KFM71158.1 - 0.018 15.1 71.7 5.2 7.3 0.3 14.6 15 0 0 15 15 15 0 DBF zinc finger NAD_kinase PF01513.21 KFM71158.1 - 0.08 12.1 0.1 6.6 5.8 0.0 3.1 1 1 2 3 3 3 0 ATP-NAD kinase BolA PF01722.18 KFM71158.1 - 0.083 13.2 31.5 2 8.7 0.0 8.5 3 1 4 9 9 8 0 BolA-like protein OSTMP1 PF09777.9 KFM71158.1 - 1.6 8.1 61.1 0.095 12.1 23.3 4.9 1 1 1 3 3 3 0 Osteopetrosis-associated transmembrane protein 1 precursor DNA_pol3_chi PF04364.13 KFM71158.1 - 8.3 6.6 7.8 28 4.9 0.1 5.0 3 2 1 6 6 6 0 DNA polymerase III chi subunit, HolC Polbeta PF18765.1 KFM71159.1 - 0.094 12.8 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-H2C2_2 PF13465.6 KFM71160.1 - 4e-74 242.0 70.4 3.1e-08 33.7 1.0 11.1 11 0 0 11 11 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71160.1 - 3.6e-47 156.2 81.3 2.6e-06 27.6 3.7 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71160.1 - 4.8e-36 120.3 76.2 0.00032 21.3 1.2 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM71160.1 - 4.3e-25 87.3 74.6 0.00023 21.4 1.6 10.4 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM71160.1 - 3.1e-19 68.5 59.5 0.0082 16.1 0.6 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM71160.1 - 2.2e-15 56.4 58.7 0.0022 18.2 0.4 10.3 9 1 1 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM71160.1 - 2.9e-15 55.7 49.9 0.09 12.6 0.0 10.6 10 0 0 10 10 10 7 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 KFM71160.1 - 2.1e-08 33.9 43.5 2.6 8.0 0.2 10.0 2 2 8 10 10 10 3 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM71160.1 - 1.5e-06 27.9 31.7 0.27 11.2 0.1 9.1 9 0 0 9 9 9 2 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM71160.1 - 3e-06 27.2 35.4 0.1 12.7 2.5 9.0 9 1 1 10 10 10 3 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM71160.1 - 1.8e-05 24.5 23.2 0.14 12.0 0.5 7.7 2 1 5 8 8 8 2 GAGA factor zf-MYST PF17772.1 KFM71160.1 - 5.2e-05 22.8 42.4 0.56 9.9 1.2 9.2 5 3 5 10 10 10 4 MYST family zinc finger domain Tox-HNH-HHH PF15637.6 KFM71160.1 - 9.8e-05 22.5 3.9 8.2 6.6 0.0 5.0 1 1 4 6 6 6 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif BolA PF01722.18 KFM71160.1 - 0.00012 22.3 14.7 1.3 9.3 0.4 5.7 1 1 4 6 6 6 2 BolA-like protein zf-RRPl_C4 PF17026.5 KFM71160.1 - 0.00017 21.7 39.2 0.17 12.0 3.8 4.7 1 1 5 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM71160.1 - 0.00036 20.6 44.5 4.6 7.4 0.5 9.4 10 0 0 10 10 10 3 DBF zinc finger ADK_lid PF05191.14 KFM71160.1 - 0.0013 18.6 32.0 0.21 11.6 0.8 6.4 5 1 2 7 7 7 3 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 KFM71160.1 - 0.0065 16.2 3.9 0.03 14.1 0.7 8.7 10 0 0 10 10 10 4 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFM71160.1 - 0.019 15.3 71.1 3.6 8.0 0.7 9.8 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KFM71160.1 - 0.04 14.1 51.5 1 9.6 6.9 5.0 1 1 3 4 4 3 0 FYVE zinc finger DUF2256 PF10013.9 KFM71160.1 - 0.047 13.8 37.4 15 5.8 0.1 9.8 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFM71160.1 - 0.11 13.2 40.7 2.1 9.2 0.7 5.4 2 1 2 6 6 6 0 zinc-ribbon family DUF952 PF06108.12 KFM71160.1 - 0.14 12.2 0.2 1.1e+02 3.0 0.0 4.1 2 2 3 5 5 5 0 Protein of unknown function (DUF952) HNH_5 PF14279.6 KFM71160.1 - 9.5 6.2 42.6 0.12 12.3 1.4 7.7 6 4 0 6 6 6 0 HNH endonuclease DUF5641 PF18701.1 KFM71161.1 - 2.2e-17 63.0 0.1 3.5e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5641) zf-H2C2_2 PF13465.6 KFM71162.1 - 3.4e-53 175.8 63.2 1e-07 32.0 0.7 9.5 10 0 0 10 10 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71162.1 - 4.9e-36 121.2 72.9 3.2e-06 27.3 1.2 9.1 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71162.1 - 3.8e-24 83.3 68.4 0.001 19.7 1.0 8.6 9 0 0 9 9 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM71162.1 - 5.3e-15 55.2 54.9 0.013 15.9 1.4 8.5 8 0 0 8 8 8 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM71162.1 - 4.7e-13 48.8 56.9 0.0096 15.9 0.9 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM71162.1 - 1.9e-11 44.0 43.6 0.0025 18.0 0.3 8.4 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM71162.1 - 2.9e-08 33.3 41.0 0.044 13.6 0.1 8.3 8 0 0 8 8 8 5 C2H2-type zinc-finger domain GAGA PF09237.11 KFM71162.1 - 1.7e-07 30.9 10.6 3.5 7.5 0.0 6.8 2 2 6 8 8 8 3 GAGA factor zf-C2H2_9 PF16293.5 KFM71162.1 - 5.1e-07 29.4 27.2 3 7.7 0.2 8.1 1 1 7 8 8 8 2 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM71162.1 - 3.8e-05 23.9 11.8 0.0081 16.4 0.2 4.5 1 1 4 5 5 5 2 BolA-like protein ADK_lid PF05191.14 KFM71162.1 - 4.3e-05 23.4 21.4 0.0024 17.8 0.2 5.8 3 2 3 6 6 6 2 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM71162.1 - 0.0011 19.1 1.5 8.4 6.6 0.1 4.0 1 1 4 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-RRPl_C4 PF17026.5 KFM71162.1 - 0.0019 18.2 29.4 0.2 11.7 6.7 4.2 1 1 4 5 5 5 3 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 KFM71162.1 - 0.0032 17.3 42.3 1.2 9.1 5.9 7.9 2 2 5 8 8 8 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHCC PF10276.9 KFM71162.1 - 0.006 16.6 9.1 15 5.8 0.0 6.5 7 0 0 7 7 7 0 Zinc-finger domain zinc_ribbon_15 PF17032.5 KFM71162.1 - 0.01 16.6 27.4 1.6 9.5 0.9 4.4 1 1 1 4 4 4 0 zinc-ribbon family DZR PF12773.7 KFM71162.1 - 0.025 14.6 24.7 0.67 10.0 0.4 4.7 1 1 1 2 2 1 0 Double zinc ribbon zf-C2H2_11 PF16622.5 KFM71162.1 - 0.033 13.9 0.2 0.033 13.9 0.2 7.5 8 0 0 8 8 8 0 zinc-finger C2H2-type DUF2256 PF10013.9 KFM71162.1 - 0.042 14.0 28.6 17 5.6 0.1 8.0 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) PqqA PF08042.11 KFM71162.1 - 0.045 13.8 4.2 83 3.4 0.0 5.6 6 0 0 6 6 6 0 PqqA family zf-C2H2_2 PF12756.7 KFM71162.1 - 0.088 13.2 54.7 2.3 8.6 2.0 8.0 1 1 5 7 7 7 0 C2H2 type zinc-finger (2 copies) DUF5330 PF17264.2 KFM71162.1 - 0.091 12.8 16.8 20 5.3 0.0 7.0 7 0 0 7 7 7 0 Family of unknown function (DUF5330) zf-HIT PF04438.16 KFM71162.1 - 0.21 11.5 41.1 2.1 8.3 1.3 8.0 8 0 0 8 8 8 0 HIT zinc finger zf-MYST PF17772.1 KFM71162.1 - 0.22 11.2 42.0 0.66 9.6 1.0 7.9 2 2 6 8 8 8 0 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 KFM71162.1 - 0.22 11.6 21.1 3.5 7.7 0.1 7.2 8 0 0 8 8 8 0 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM71162.1 - 0.32 11.1 35.8 7.1 6.8 0.2 7.7 7 1 1 8 8 8 0 DBF zinc finger zf-met2 PF12907.7 KFM71162.1 - 0.36 11.0 0.2 0.36 11.0 0.2 7.7 8 1 0 8 8 8 0 Zinc-binding zf-C2HC_2 PF13913.6 KFM71162.1 - 0.65 10.0 31.1 1.6 8.7 0.1 7.5 8 0 0 8 8 7 0 zinc-finger of a C2HC-type zf-FPG_IleRS PF06827.14 KFM71162.1 - 0.9 9.5 25.1 58 3.7 0.1 7.6 8 0 0 8 8 8 0 Zinc finger found in FPG and IleRS PknG_rubred PF16919.5 KFM71162.1 - 2.2 8.4 5.0 34 4.6 0.0 3.8 2 1 1 4 4 4 0 Protein kinase G rubredoxin domain FYVE PF01363.21 KFM71162.1 - 3.2 8.0 39.8 1.9 8.7 8.4 5.1 1 1 4 5 5 5 0 FYVE zinc finger Scramblase PF03803.15 KFM71162.1 - 4.8 6.4 6.6 1.1 8.5 0.7 2.4 1 1 2 3 3 3 0 Scramblase DDE_Tnp_1_7 PF13843.6 KFM71163.1 - 6.1e-11 42.2 0.1 6.6e-11 42.1 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 zf-CCHC PF00098.23 KFM71164.1 - 9.5e-18 63.4 23.3 7.8e-05 22.6 0.8 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KFM71164.1 - 7.2e-05 22.5 26.5 0.0073 16.1 1.1 4.3 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 KFM71164.1 - 0.0018 17.9 20.5 0.31 10.8 0.8 4.6 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.6 KFM71164.1 - 0.02 14.8 0.8 0.02 14.8 0.8 4.2 3 1 1 4 4 4 0 Zinc knuckle TPM_phosphatase PF04536.14 KFM71164.1 - 0.02 15.0 0.4 3.3 7.9 0.0 3.0 3 0 0 3 3 3 0 TPM domain PID PF00640.23 KFM71165.1 - 9.1e-35 119.7 0.0 1.4e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KFM71165.1 - 2.5e-16 59.5 0.0 4.6e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 SH2 domain NICE-3 PF07406.11 KFM71166.1 - 0.00068 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 NICE-3 protein FXa_inhibition PF14670.6 KFM71168.1 - 8.9e-23 80.3 27.4 3.8e-10 39.9 8.4 3.0 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFM71168.1 - 1.2e-17 63.5 5.9 4.1e-06 26.6 0.4 3.6 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_3 PF12947.7 KFM71168.1 - 0.004 17.3 28.2 0.13 12.5 3.8 3.6 3 0 0 3 3 3 2 EGF domain Tme5_EGF_like PF09064.10 KFM71168.1 - 0.0051 16.7 17.8 0.58 10.1 3.3 3.4 3 0 0 3 3 3 3 Thrombomodulin like fifth domain, EGF-like EGF_CA PF07645.15 KFM71168.1 - 0.086 13.1 23.0 1.2 9.4 5.5 3.3 3 0 0 3 3 3 0 Calcium-binding EGF domain TIL PF01826.17 KFM71168.1 - 0.23 11.8 22.9 4.9 7.5 1.2 3.5 1 1 2 3 3 3 0 Trypsin Inhibitor like cysteine rich domain Omega-toxin PF06357.11 KFM71168.1 - 0.34 10.7 12.4 3.7 7.4 0.6 3.3 1 1 1 2 2 2 0 Omega-atracotoxin RANK_CRD_2 PF18278.1 KFM71168.1 - 2.4 8.4 14.6 2.5 8.3 0.5 3.3 3 0 0 3 3 3 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 PIF3 PF05006.12 KFM71168.1 - 5.3 7.1 19.8 9.1 6.4 10.4 2.9 1 1 2 3 3 3 0 Per os infectivity factor 3 EGF PF00008.27 KFM71168.1 - 6.3 7.2 24.1 26 5.2 0.1 3.8 2 1 0 3 3 3 0 EGF-like domain Albumin_I_a PF16720.5 KFM71168.1 - 7.4 6.6 12.9 1.3 9.0 3.0 2.5 2 0 0 2 2 2 0 Albumin I chain a Toxin_21 PF08091.11 KFM71168.1 - 7.4 6.6 13.8 6.2 6.8 2.6 2.9 2 1 0 2 2 2 0 Spider insecticidal peptide DUF4215 PF13948.6 KFM71168.1 - 9 6.8 26.1 24 5.5 7.0 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4215) Laminin_EGF PF00053.24 KFM71170.1 - 9.3e-25 86.5 125.3 1.1e-05 25.4 15.0 8.5 2 2 6 8 8 8 8 Laminin EGF domain EGF_2 PF07974.13 KFM71170.1 - 1e-12 48.1 151.1 0.033 14.5 5.9 13.0 10 4 1 11 11 11 9 EGF-like domain hEGF PF12661.7 KFM71170.1 - 3.6e-08 33.7 107.5 3.1e-05 24.4 2.8 11.2 11 0 0 11 11 11 6 Human growth factor-like EGF DSL PF01414.19 KFM71170.1 - 7.5e-06 26.1 126.5 7.2e-05 23.0 8.6 7.3 6 1 1 7 7 7 5 Delta serrate ligand EGF PF00008.27 KFM71170.1 - 0.0021 18.3 123.2 0.021 15.2 10.9 11.6 10 3 0 10 10 10 5 EGF-like domain APG6_N PF17675.1 KFM71171.1 - 0.0015 19.0 7.9 0.0015 19.0 7.9 7.4 1 1 6 7 7 7 3 Apg6 coiled-coil region Spc7 PF08317.11 KFM71171.1 - 0.0017 17.3 25.1 0.0017 17.3 25.1 5.0 2 1 3 5 5 5 3 Spc7 kinetochore protein Fib_alpha PF08702.10 KFM71171.1 - 0.71 10.0 83.7 0.44 10.7 10.9 6.3 3 1 3 6 6 6 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 KFM71171.1 - 1.1 7.4 93.3 0.058 11.6 10.1 4.2 1 1 3 4 4 4 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 KFM71171.1 - 1.2 9.2 72.9 0.14 12.2 5.1 7.0 3 1 5 8 8 8 0 Protein of unknown function (DUF1664) ComX PF05952.12 KFM71171.1 - 2.6 8.1 6.2 1.1 9.2 0.7 2.7 2 0 0 2 2 2 0 Bacillus competence pheromone ComX DUF4371 PF14291.6 KFM71172.1 - 1e-29 103.9 2.4 1.8e-29 103.0 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM71172.1 - 1.5e-11 43.9 0.4 3.6e-11 42.7 0.4 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KFM71172.1 - 0.044 13.6 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) PfUIS3 PF11567.8 KFM71172.1 - 0.25 11.7 5.7 0.12 12.8 1.4 2.8 2 1 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein Rootletin PF15035.6 KFM71173.1 - 9.2e-16 58.4 20.6 6.8e-15 55.6 6.6 5.5 2 2 2 4 4 4 3 Ciliary rootlet component, centrosome cohesion DDE_Tnp_1_7 PF13843.6 KFM71173.1 - 1.7e-15 57.2 3.4 3.5e-15 56.2 0.0 2.8 3 1 0 4 4 4 1 Transposase IS4 Pex14_N PF04695.13 KFM71173.1 - 0.31 11.7 0.0 0.31 11.7 0.0 2.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosom_S12_S23 PF00164.25 KFM71174.1 - 3.8e-52 174.7 0.6 4.6e-52 174.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 KFM71174.1 - 0.072 12.7 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase An_peroxidase PF03098.15 KFM71175.1 - 1.1e-20 73.8 0.0 1.1e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 KFM71176.1 - 4.8e-29 101.3 0.0 5e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase NRD1_2 PF01995.16 KFM71177.1 - 0.27 10.5 0.0 0.31 10.3 0.0 1.0 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 Pro_dh PF01619.18 KFM71178.1 - 8.1e-65 219.3 0.1 1.1e-64 218.8 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Pro_dh PF01619.18 KFM71179.1 - 1e-11 44.9 0.0 1.3e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase Pro_dh PF01619.18 KFM71180.1 - 7.8e-12 45.3 0.3 8.2e-12 45.3 0.3 1.0 1 0 0 1 1 1 1 Proline dehydrogenase NifW PF03206.14 KFM71183.1 - 0.083 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Nitrogen fixation protein NifW DUF937 PF06078.11 KFM71185.1 - 0.048 14.3 0.0 0.057 14.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) KH_9 PF17904.1 KFM71188.1 - 7.6e-29 99.9 0.2 2e-28 98.6 0.2 1.8 1 0 0 1 1 1 1 FMRP KH0 domain Tudor_FRX1 PF18336.1 KFM71188.1 - 1.9e-26 91.7 0.8 4.3e-26 90.6 0.1 1.9 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain KH_1 PF00013.29 KFM71188.1 - 9e-16 57.5 2.7 8.7e-08 31.9 1.6 2.9 3 0 0 3 3 3 2 KH domain Agenet PF05641.12 KFM71188.1 - 4.2e-14 52.8 3.4 1.6e-07 31.7 0.2 3.5 4 0 0 4 4 4 2 Agenet domain FXMRP1_C_core PF12235.8 KFM71188.1 - 7.8e-14 52.5 15.1 7.8e-14 52.5 15.1 3.0 2 1 0 2 2 2 1 Fragile X-related 1 protein core C terminal KH_2 PF07650.17 KFM71188.1 - 0.023 14.5 2.5 0.86 9.5 0.0 2.7 2 0 0 2 2 2 0 KH domain SH3_1 PF00018.28 KFM71188.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 SH3 domain KH_4 PF13083.6 KFM71188.1 - 0.11 12.4 3.5 1.8 8.5 0.7 2.9 2 1 1 3 3 3 0 KH domain KH_5 PF13184.6 KFM71188.1 - 0.13 12.4 1.1 1 9.5 0.6 2.4 2 0 0 2 2 2 0 NusA-like KH domain Yip1 PF04893.17 KFM71190.1 - 7e-10 38.9 10.2 9.7e-10 38.4 10.2 1.2 1 0 0 1 1 1 1 Yip1 domain CsgF PF10614.9 KFM71190.1 - 0.4 10.9 1.7 0.61 10.3 1.7 1.2 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein Actin PF00022.19 KFM71192.1 - 1.5e-86 290.5 0.0 1.1e-85 287.7 0.0 1.8 1 1 0 1 1 1 1 Actin adh_short PF00106.25 KFM71193.1 - 3.3e-28 98.5 0.0 4.4e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM71193.1 - 3e-15 56.4 0.0 3.7e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM71193.1 - 1.2e-05 25.3 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF2791 PF10923.8 KFM71195.1 - 0.039 12.8 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) COesterase PF00135.28 KFM71196.1 - 6.5e-94 315.6 0.0 7.8e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM71196.1 - 3.1e-10 40.3 0.0 7.2e-10 39.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM71196.1 - 0.011 15.2 0.1 0.02 14.4 0.1 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF5075 PF16825.5 KFM71196.1 - 0.044 13.5 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 IGP family C-type lectin domain LysM PF01476.20 KFM71197.1 - 6.4e-10 38.9 0.2 3.2e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 LysM domain DUF3719 PF12516.8 KFM71197.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Ras PF00071.22 KFM71198.1 - 7.5e-15 54.9 0.3 1.7e-14 53.7 0.3 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFM71198.1 - 8.6e-08 32.4 0.1 2.2e-06 27.9 0.1 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KFM71198.1 - 0.0041 16.9 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM71198.1 - 0.01 15.8 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFM71198.1 - 0.013 14.8 0.0 0.055 12.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KFM71198.1 - 0.017 15.6 0.0 0.034 14.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFM71198.1 - 0.039 13.5 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2179 PF10035.9 KFM71198.1 - 0.04 13.7 0.6 0.2 11.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) AAA_22 PF13401.6 KFM71198.1 - 0.057 13.7 0.0 0.22 11.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFM71198.1 - 0.068 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KFM71198.1 - 0.09 11.7 0.4 1.6 7.5 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Ras PF00071.22 KFM71202.1 - 4.1e-23 81.8 0.2 6.6e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM71202.1 - 2.3e-05 24.6 0.0 0.00069 19.8 0.0 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFM71202.1 - 0.00026 21.0 0.1 0.025 14.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 KFM71202.1 - 0.064 13.6 0.1 0.23 11.9 0.1 2.0 1 1 0 1 1 1 0 RNA helicase HTH_Tnp_Tc3_2 PF01498.18 KFM71203.1 - 2.1e-16 59.9 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71203.1 - 8.9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L14 PF00238.19 KFM71204.1 - 8.1e-33 113.1 0.6 9.6e-33 112.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e GKAP PF03359.13 KFM71205.1 - 5.4e-37 128.1 14.4 1.8e-36 126.5 14.4 1.9 1 1 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein Ribosomal_L35p PF01632.19 KFM71206.1 - 8.2e-11 42.2 0.2 1.1e-10 41.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 CBM_3 PF00942.18 KFM71207.1 - 0.026 14.9 0.1 0.028 14.8 0.1 1.1 1 0 0 1 1 1 0 Cellulose binding domain Guanylate_kin PF00625.21 KFM71208.1 - 6.3e-69 231.3 0.3 9.7e-69 230.7 0.3 1.3 1 0 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.28 KFM71208.1 - 1.4e-08 34.2 0.2 3.5e-08 32.9 0.2 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM71208.1 - 2.5e-08 33.5 0.0 5.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFM71208.1 - 0.00097 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_L18_c PF14204.6 KFM71208.1 - 0.1 13.5 0.2 0.1 13.5 0.2 2.1 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region SF3A2 PF16835.5 KFM71209.1 - 2.4e-38 130.4 0.1 3.7e-38 129.8 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KFM71209.1 - 3.7e-07 30.3 2.0 7.7e-07 29.3 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KFM71209.1 - 0.0003 20.7 0.2 0.00058 19.8 0.2 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KFM71209.1 - 0.073 12.6 3.2 0.12 11.9 3.2 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like TBPIP PF07106.13 KFM71210.1 - 2.7e-24 84.9 0.5 6.1e-24 83.7 0.5 1.6 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 KFM71210.1 - 1.8e-12 47.1 0.8 5.9e-12 45.5 0.8 1.9 1 0 0 1 1 1 1 Leucine zipper with capping helix domain HR1 PF02185.16 KFM71210.1 - 0.0011 19.0 2.7 0.0033 17.5 2.7 1.8 1 0 0 1 1 1 1 Hr1 repeat Penicillinase_R PF03965.16 KFM71210.1 - 0.003 17.9 0.6 0.0066 16.8 0.2 2.0 2 1 0 2 2 2 1 Penicillinase repressor Laminin_II PF06009.12 KFM71210.1 - 0.0038 17.2 4.6 0.0071 16.4 4.6 1.4 1 0 0 1 1 1 1 Laminin Domain II Fez1 PF06818.15 KFM71210.1 - 0.0051 17.3 9.2 0.0076 16.7 9.2 1.3 1 0 0 1 1 1 1 Fez1 Cnn_1N PF07989.11 KFM71210.1 - 0.0071 16.5 10.0 0.011 15.8 3.8 2.6 2 1 0 2 2 2 1 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 KFM71210.1 - 0.023 14.7 9.7 0.33 11.0 9.7 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KFM71210.1 - 0.028 14.5 1.8 0.053 13.6 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) YgaB PF14182.6 KFM71210.1 - 0.039 14.3 4.8 1.3 9.5 0.4 3.1 1 1 2 3 3 3 0 YgaB-like protein SlyX PF04102.12 KFM71210.1 - 0.048 14.3 4.3 0.25 12.0 1.8 2.4 1 1 1 2 2 2 0 SlyX DUF148 PF02520.17 KFM71210.1 - 0.14 12.3 8.4 0.36 11.0 2.1 2.7 1 1 1 2 2 2 0 Domain of unknown function DUF148 Allexi_40kDa PF05549.11 KFM71210.1 - 0.16 11.5 3.0 0.2 11.2 3.0 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein USP8_interact PF08941.10 KFM71210.1 - 0.34 10.7 3.5 0.36 10.6 2.3 1.7 2 0 0 2 2 2 0 USP8 interacting FlxA PF14282.6 KFM71210.1 - 0.37 10.8 7.0 1.9 8.5 7.0 2.2 1 1 0 1 1 1 0 FlxA-like protein DUF4140 PF13600.6 KFM71210.1 - 1.6 9.2 4.5 17 5.9 0.1 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Muted PF14942.6 KFM71210.1 - 1.7 9.0 10.3 2.1 8.7 9.2 1.8 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein APG6_N PF17675.1 KFM71210.1 - 2.4 8.7 14.1 9.2 6.8 12.5 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF2203 PF09969.9 KFM71210.1 - 8.3 7.2 7.4 4.5 8.0 2.4 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) LMBR1 PF04791.16 KFM71210.1 - 9.1 5.1 5.4 9.9 4.9 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PIP5K PF01504.18 KFM71211.1 - 1.5e-93 313.0 0.1 2.2e-93 312.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase RTC4 PF14474.6 KFM71211.1 - 0.013 15.7 0.1 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 RTC4-like domain DDE_3 PF13358.6 KFM71212.1 - 6.6e-16 58.4 0.1 8.1e-15 54.8 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71212.1 - 1.4e-10 41.2 1.0 2.8e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase gag-asp_proteas PF13975.6 KFM71215.1 - 4.9e-06 27.0 0.0 5.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM71215.1 - 4.9e-05 23.9 0.0 5.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM71215.1 - 5.6e-05 23.4 0.0 6.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KFM71215.1 - 0.0095 15.7 0.0 0.0098 15.7 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KFM71215.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.2 1 1 0 1 1 1 0 Aspartyl protease C2 PF00168.30 KFM71216.1 - 9.2e-14 51.6 0.0 1.1e-13 51.3 0.0 1.0 1 0 0 1 1 1 1 C2 domain Flu_NS1 PF00600.19 KFM71216.1 - 0.017 14.7 0.0 0.019 14.5 0.0 1.0 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) Self-incomp_S1 PF05938.11 KFM71221.1 - 1.2e-11 45.0 0.1 2e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Plant self-incompatibility protein S1 DDE_3 PF13358.6 KFM71222.1 - 1.4e-09 37.9 0.0 2.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5641 PF18701.1 KFM71222.1 - 0.00016 21.7 2.0 0.0014 18.7 0.3 2.9 3 0 0 3 3 3 1 Family of unknown function (DUF5641) HTH_3 PF01381.22 KFM71222.1 - 0.012 15.6 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM71222.1 - 0.016 15.2 0.1 0.044 13.8 0.1 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KFM71222.1 - 0.022 14.7 0.3 0.057 13.3 0.3 1.7 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 KFM71222.1 - 0.098 12.5 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KFM71222.1 - 0.12 12.5 1.5 0.27 11.4 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain CPG4 PF15481.6 KFM71224.1 - 3 8.5 8.4 0.64 10.7 4.5 2.0 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 HTH_Tnp_Tc3_2 PF01498.18 KFM71225.1 - 2.5e-16 59.7 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71225.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71225.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71225.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71225.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain I-set PF07679.16 KFM71227.1 - 0 1102.2 76.4 1.1e-22 79.9 0.1 18.0 18 0 0 18 18 18 18 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM71227.1 - 1.2e-218 708.4 30.2 8.9e-15 55.1 0.1 17.4 17 0 0 17 17 17 17 Immunoglobulin domain Ig_2 PF13895.6 KFM71227.1 - 6.5e-123 401.3 31.5 2e-09 37.7 0.1 17.2 17 0 0 17 17 17 16 Immunoglobulin domain ig PF00047.25 KFM71227.1 - 6.5e-117 382.0 66.0 9.5e-11 41.7 0.6 17.1 18 0 0 18 18 18 16 Immunoglobulin domain V-set PF07686.17 KFM71227.1 - 8.8e-58 193.2 57.2 5.9e-05 23.2 0.5 22.7 15 11 1 16 16 16 13 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM71227.1 - 1.7e-33 114.5 12.4 0.3 11.2 0.0 15.7 15 0 0 15 15 15 7 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM71227.1 - 4.4e-33 112.6 7.9 0.014 14.9 0.0 13.8 15 0 0 15 15 15 7 Immunoglobulin domain Receptor_2B4 PF11465.8 KFM71227.1 - 7.4e-29 100.1 30.1 0.014 15.6 0.1 14.2 13 1 1 14 14 14 6 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFM71227.1 - 6.8e-23 80.5 34.1 0.23 11.5 0.1 15.0 16 0 0 16 16 16 7 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFM71227.1 - 9.3e-21 74.0 41.4 0.084 13.3 0.2 15.6 15 0 0 15 15 15 5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM71227.1 - 8.8e-19 67.5 44.4 0.43 10.9 0.1 15.6 15 0 0 15 15 15 5 T-cell surface glycoprotein CD3 delta chain Egh16-like PF11327.8 KFM71227.1 - 2.9e-13 50.6 25.3 0.017 15.6 0.5 10.1 6 3 2 10 10 10 3 Egh16-like virulence factor C1-set PF07654.15 KFM71227.1 - 4.8e-12 46.1 30.5 0.87 10.0 0.2 14.1 15 0 0 15 15 15 2 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFM71227.1 - 8.6e-11 41.7 19.0 7.3 6.7 0.0 13.6 15 0 0 15 15 15 0 C17orf99 Ig domain C2-set PF05790.15 KFM71227.1 - 2.7e-08 33.9 42.2 0.62 10.3 0.3 13.3 12 2 1 13 13 13 2 Immunoglobulin C2-set domain V-set_CD47 PF08204.11 KFM71227.1 - 4.4e-08 33.2 45.3 0.74 9.8 0.2 13.9 14 1 0 14 14 14 3 CD47 immunoglobulin-like domain BiPBP_C PF06832.12 KFM71227.1 - 3.1e-07 30.3 0.0 2 8.5 0.0 9.3 12 0 0 12 12 11 1 Penicillin-Binding Protein C-terminus Family SLAM PF06214.11 KFM71227.1 - 0.0003 20.8 1.9 4.4 7.3 0.1 5.2 6 0 0 6 6 5 2 Signaling lymphocytic activation molecule (SLAM) protein V-set_2 PF15910.5 KFM71227.1 - 0.00068 19.7 11.4 11 6.1 0.0 8.7 9 1 1 10 10 9 0 ICOS V-set domain Pup_ligase PF03136.15 KFM71227.1 - 0.094 11.7 1.4 0.72 8.8 0.8 2.4 1 1 2 3 3 3 0 Pup-ligase protein MBG_2 PF18676.1 KFM71227.1 - 0.13 12.9 54.0 1.2 9.9 0.2 13.4 13 1 0 14 14 13 0 MBG domain (YGX type) PEGA PF08308.11 KFM71227.1 - 0.16 11.9 3.3 28 4.7 0.1 4.7 3 0 0 3 3 3 0 PEGA domain TIG_plexin PF17960.1 KFM71227.1 - 0.17 11.9 21.1 0.73 9.9 0.1 8.1 9 0 0 9 9 9 0 TIG domain DUF3724 PF12521.8 KFM71227.1 - 0.18 11.7 12.2 27 4.9 0.0 6.5 8 0 0 8 8 7 0 Protein of unknown function (DUF3724) CarboxypepD_reg PF13620.6 KFM71227.1 - 0.31 11.3 16.0 29 5.0 0.0 7.7 8 1 0 8 8 5 0 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 KFM71227.1 - 0.46 10.8 44.9 1.1 9.6 0.2 10.8 6 2 2 11 11 11 0 Domain of unknown function (DUF4198) WBS_methylT PF12589.8 KFM71227.1 - 0.55 11.0 3.1 4.1 8.2 0.8 3.5 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Calci_bind_CcbP PF11535.8 KFM71227.1 - 0.69 10.4 3.9 1.4 9.4 0.0 3.6 3 0 0 3 3 2 0 Calcium binding DUF1533 PF07550.11 KFM71227.1 - 0.81 9.6 22.9 2.3 8.2 0.1 7.5 8 0 0 8 8 6 0 Protein of unknown function (DUF1533) BsuPI PF12690.7 KFM71227.1 - 8.6 6.5 13.2 71 3.5 0.1 7.4 9 1 0 9 9 5 0 Intracellular proteinase inhibitor I-set PF07679.16 KFM71228.1 - 1.5e-32 111.5 0.0 1.6e-16 60.1 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM71228.1 - 5.8e-23 81.3 0.0 3e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM71228.1 - 3.3e-11 43.2 0.0 0.00015 21.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM71228.1 - 3.6e-08 33.6 0.0 0.00017 21.8 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM71228.1 - 4e-07 30.2 0.0 0.033 14.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM71228.1 - 5.9e-05 23.1 0.0 0.06 13.4 0.0 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 KFM71228.1 - 0.0042 17.3 0.0 0.037 14.2 0.0 2.1 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 MBG_2 PF18676.1 KFM71228.1 - 0.016 15.8 0.1 0.038 14.6 0.1 1.6 1 0 0 1 1 1 0 MBG domain (YGX type) Izumo-Ig PF16706.5 KFM71228.1 - 0.099 12.7 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain I-set PF07679.16 KFM71229.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFM71229.1 - 0.016 15.4 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM71229.1 - 0.12 13.0 0.1 0.24 12.0 0.0 1.5 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 KFM71230.1 - 8.1e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM71230.1 - 0.0017 18.9 0.0 0.0044 17.6 0.0 1.7 1 1 1 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFM71230.1 - 0.007 16.5 0.0 0.014 15.5 0.0 1.5 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM71230.1 - 0.036 14.4 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain PID PF00640.23 KFM71231.1 - 3.5e-05 23.9 2.0 7.8e-05 22.7 1.9 1.8 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) TbpB_A PF17484.2 KFM71231.1 - 0.16 12.7 1.3 0.27 12.0 0.4 1.8 2 1 0 2 2 2 0 N-Lobe handle Tf-binding protein B DDE_3 PF13358.6 KFM71232.1 - 3.6e-16 59.2 0.1 6.2e-15 55.2 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71232.1 - 7.5e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71232.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71232.1 - 0.0026 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71232.1 - 0.015 15.4 0.1 0.066 13.3 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71232.1 - 0.035 14.1 2.6 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix zf-C2H2 PF00096.26 KFM71234.1 - 4.1e-13 49.0 32.4 2.7e-05 24.4 5.0 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM71234.1 - 7e-13 48.4 10.5 9.6e-09 35.3 2.4 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM71234.1 - 1.5e-06 28.5 31.5 0.00045 20.8 4.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KFM71234.1 - 0.0042 17.4 6.9 0.081 13.3 1.2 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM71234.1 - 0.025 14.9 0.3 0.025 14.9 0.3 3.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KFM71234.1 - 2.6 8.8 12.9 2.4 8.9 2.5 2.9 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFM71234.1 - 2.6 8.1 17.0 0.28 11.2 3.8 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger Haspin_kinase PF12330.8 KFM71235.1 - 1.1e-29 103.6 1.2 1.2e-29 103.4 1.2 1.0 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_Tyr PF07714.17 KFM71235.1 - 0.00039 19.8 0.0 0.0018 17.6 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFM71235.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family HTH_Tnp_Tc3_2 PF01498.18 KFM71236.1 - 3.6e-16 59.2 3.0 6.3e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71236.1 - 1.4e-13 50.9 0.0 2.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71236.1 - 2.9e-07 30.1 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71236.1 - 0.0029 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71236.1 - 0.032 14.3 0.4 0.098 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM71236.1 - 2.7 8.7 15.6 0.13 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 KFM71238.1 - 1.4e-54 180.2 94.1 9.6e-09 35.3 0.4 12.1 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71238.1 - 3.8e-40 134.1 108.2 2.6e-05 24.4 1.6 11.6 12 0 0 12 12 12 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71238.1 - 3.2e-26 89.7 97.6 0.00064 20.3 1.2 11.6 12 0 0 12 12 12 10 C2H2-type zinc finger zf-met PF12874.7 KFM71238.1 - 4.6e-24 84.0 81.2 0.00067 20.0 0.5 11.3 11 0 0 11 11 11 9 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM71238.1 - 2.9e-14 52.5 58.8 0.0027 17.4 1.7 10.5 11 0 0 11 11 11 7 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM71238.1 - 7.4e-14 51.6 56.7 0.0031 17.7 0.2 10.6 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM71238.1 - 6e-13 48.3 72.9 8.9e-07 28.6 1.5 11.5 12 0 0 12 12 12 6 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM71238.1 - 3.2e-12 46.1 81.9 0.019 14.9 0.9 11.7 12 0 0 12 12 12 7 C2H2-type zinc finger zf-RRPl_C4 PF17026.5 KFM71238.1 - 1.2e-06 28.6 49.0 0.0012 18.9 8.8 5.1 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM71238.1 - 1e-05 25.5 45.4 0.57 10.3 0.3 9.8 10 0 0 10 10 10 4 Uncharacterized protein conserved in bacteria (DUF2256) zf-Sec23_Sec24 PF04810.15 KFM71238.1 - 0.00017 21.5 34.5 1.2 9.3 0.2 9.5 4 2 6 10 10 10 1 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM71238.1 - 0.00034 20.3 23.4 3 7.7 0.0 7.9 3 2 6 9 9 9 2 GAGA factor BolA PF01722.18 KFM71238.1 - 0.038 14.3 24.0 0.62 10.4 0.3 6.8 2 2 6 8 8 8 0 BolA-like protein zf-C2H2_9 PF16293.5 KFM71238.1 - 0.08 12.8 46.8 2.7 7.9 0.2 9.5 6 3 5 11 11 10 0 C2H2 type zinc-finger (1 copy) zf-CHCC PF10276.9 KFM71238.1 - 0.094 12.8 17.3 55 3.9 0.0 8.0 9 0 0 9 9 9 0 Zinc-finger domain zf-MYST PF17772.1 KFM71238.1 - 0.15 11.6 0.2 0.15 11.6 0.2 9.0 8 2 2 10 10 10 0 MYST family zinc finger domain C1_1 PF00130.22 KFM71238.1 - 0.26 11.2 69.4 1.5 8.8 3.1 9.4 5 3 2 8 8 8 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 KFM71238.1 - 0.54 10.4 60.4 3.9 7.7 9.0 6.1 1 1 5 6 6 5 0 FYVE zinc finger YyzF PF14116.6 KFM71238.1 - 0.76 9.9 36.8 14 5.9 0.3 9.2 10 0 0 10 10 10 0 YyzF-like protein ADK_lid PF05191.14 KFM71238.1 - 0.92 9.5 40.9 1.1 9.4 3.8 7.4 4 2 6 10 10 10 0 Adenylate kinase, active site lid Mga PF05043.13 KFM71238.1 - 1.1 9.9 6.9 27 5.4 0.4 4.1 3 2 2 5 5 5 0 Mga helix-turn-helix domain zf-C2H2_2 PF12756.7 KFM71238.1 - 1.2 9.5 83.3 3 8.2 0.4 9.1 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM71239.1 - 2.6e-15 56.0 12.9 1.2e-08 34.9 1.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71239.1 - 8e-10 38.6 15.9 1.1e-05 25.6 3.6 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71239.1 - 2.1e-07 31.2 14.0 0.00039 21.0 2.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM71239.1 - 1.5e-06 28.3 6.2 0.012 15.9 0.6 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM71239.1 - 3.9e-06 27.1 11.9 0.0018 18.6 2.4 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM71239.1 - 9.3e-05 22.1 6.5 0.025 14.3 0.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM71239.1 - 0.00012 22.0 8.9 0.017 15.1 2.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM71239.1 - 0.00043 20.0 7.4 0.032 14.0 0.7 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type GAGA PF09237.11 KFM71239.1 - 0.00057 19.6 0.1 0.24 11.3 0.0 2.0 1 1 1 2 2 2 2 GAGA factor zf-RRPl_C4 PF17026.5 KFM71239.1 - 0.0029 17.7 1.2 0.0032 17.5 1.2 1.1 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM71239.1 - 0.0058 16.7 1.4 0.76 9.9 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KFM71239.1 - 0.012 15.9 10.8 0.21 11.9 1.8 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Inhibitor_I67 PF11405.8 KFM71239.1 - 0.013 15.8 0.5 4.9 7.5 0.2 2.1 2 0 0 2 2 2 0 Bromelain inhibitor VI C1_1 PF00130.22 KFM71239.1 - 0.017 15.0 7.1 0.72 9.8 0.7 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TRAF6_Z2 PF18048.1 KFM71239.1 - 0.032 14.3 4.7 0.18 11.9 0.7 2.6 2 2 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_8 PF15909.5 KFM71239.1 - 0.048 14.0 4.4 0.052 13.8 4.4 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-Paramyx-P PF13008.7 KFM71239.1 - 0.08 12.4 1.0 9.8 5.7 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein DUF2072 PF09845.9 KFM71239.1 - 0.13 12.5 3.4 5.7 7.2 0.2 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein zf-C2H2_9 PF16293.5 KFM71239.1 - 0.17 11.8 3.9 4.4 7.2 0.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM71239.1 - 0.19 11.9 5.5 0.37 11.0 5.5 1.5 1 1 0 1 1 1 0 FYVE zinc finger YyzF PF14116.6 KFM71239.1 - 0.19 11.7 4.5 4.1 7.5 0.4 2.2 1 1 1 2 2 2 0 YyzF-like protein zf-DBF PF07535.12 KFM71239.1 - 0.21 11.7 4.3 0.69 10.1 1.0 2.4 2 1 0 2 2 2 0 DBF zinc finger zf-C2HC_2 PF13913.6 KFM71239.1 - 0.23 11.4 4.7 4.8 7.2 0.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 KFM71239.1 - 0.28 11.7 7.3 5 7.7 0.3 2.5 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Vps39_2 PF10367.9 KFM71239.1 - 0.34 11.4 7.4 4.2 7.9 0.8 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF5402 PF17393.2 KFM71239.1 - 0.39 10.7 2.3 5.4 7.0 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5402) zf-BED PF02892.15 KFM71239.1 - 0.4 10.7 9.4 0.31 11.1 2.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf_ZIC PF18366.1 KFM71239.1 - 2.8 8.1 8.4 0.86 9.8 1.1 2.1 1 1 1 2 2 2 0 Zic proteins zinc finger domain Snf7 PF03357.21 KFM71242.1 - 4.6e-45 153.3 29.1 5.4e-45 153.1 29.1 1.0 1 0 0 1 1 1 1 Snf7 HTH_6 PF01418.17 KFM71242.1 - 0.029 14.3 0.4 0.093 12.7 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Exonuc_VII_L PF02601.15 KFM71242.1 - 0.54 9.8 7.2 0.8 9.2 7.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit GCR1_C PF12550.8 KFM71242.1 - 0.56 10.6 5.2 0.86 10.0 2.0 2.4 2 1 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Tctex-1 PF03645.13 KFM71242.1 - 0.72 10.1 5.4 10 6.4 5.5 2.4 1 1 1 2 2 2 0 Tctex-1 family DUF4047 PF13256.6 KFM71242.1 - 4.6 7.5 11.1 0.43 10.8 3.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) DUF2229 PF09989.9 KFM71242.1 - 4.9 6.7 9.8 1.8 8.2 2.4 2.2 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) HTH_23 PF13384.6 KFM71243.1 - 0.0021 17.8 0.1 0.0025 17.6 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KFM71243.1 - 0.017 15.1 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn helix PAX PF00292.18 KFM71243.1 - 0.026 14.5 0.0 0.029 14.3 0.0 1.0 1 0 0 1 1 1 0 'Paired box' domain MarR_2 PF12802.7 KFM71243.1 - 0.046 13.6 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 MarR family Acatn PF13000.7 KFM71244.1 - 1.2e-119 400.4 24.2 2e-73 247.8 9.5 3.4 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 CBM_14 PF01607.24 KFM71245.1 - 2.4e-33 114.0 20.1 6.1e-14 51.9 2.0 4.3 2 1 2 4 4 4 4 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 KFM71246.1 - 2.7e-23 81.9 18.0 1.2e-11 44.6 4.3 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain SelP_C PF04593.14 KFM71246.1 - 0.009 16.0 3.0 0.012 15.6 2.3 1.6 1 1 0 1 1 1 1 Selenoprotein P, C terminal region bZIP_1 PF00170.21 KFM71247.1 - 2.4e-10 40.4 16.7 4e-10 39.6 16.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM71247.1 - 5.6e-07 29.5 15.0 9.8e-07 28.8 15.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper tRNA-synt_1f PF01921.18 KFM71247.1 - 0.0018 17.2 0.1 0.0031 16.5 0.1 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (K) bZIP_Maf PF03131.17 KFM71247.1 - 0.022 15.3 7.3 0.037 14.5 7.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Pro-MCH PF05824.12 KFM71247.1 - 0.033 14.1 0.3 0.082 12.8 0.3 1.6 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) DUF1515 PF07439.11 KFM71247.1 - 0.46 10.5 2.7 0.94 9.5 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Seryl_tRNA_N PF02403.22 KFM71247.1 - 3.1 8.1 12.2 1.1 9.5 8.0 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 KFM71247.1 - 8 6.3 13.1 0.2 11.5 3.0 2.3 1 1 1 2 2 2 0 Septum formation initiator Ribosomal_L7Ae PF01248.26 KFM71248.1 - 1.2e-26 92.2 0.5 1.4e-26 92.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KFM71248.1 - 0.00024 20.9 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 KFM71248.1 - 0.0026 17.8 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PhyH PF05721.13 KFM71249.1 - 5.9e-53 180.3 0.0 6.9e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KFM71249.1 - 0.0047 17.3 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase HTH_Tnp_Tc3_2 PF01498.18 KFM71250.1 - 2.4e-15 56.5 1.7 4.4e-15 55.7 1.7 1.5 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM71250.1 - 0.00047 20.2 1.3 0.0009 19.3 0.1 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM71250.1 - 0.0067 17.0 1.4 0.0067 17.0 1.4 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71250.1 - 0.031 14.1 0.0 0.088 12.6 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain CENP-B_N PF04218.13 KFM71250.1 - 0.11 12.2 0.0 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain PAX PF00292.18 KFM71250.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain HTH_Tnp_ISL3 PF13542.6 KFM71250.1 - 0.15 11.5 2.2 0.3 10.5 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Tox-GHH PF15636.6 KFM71252.1 - 8.5e-25 86.5 0.1 2.6e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.13 KFM71252.1 - 2.9e-21 75.5 142.7 5.4e-05 23.5 7.9 9.4 9 0 0 9 9 9 8 EGF-like domain RHS_repeat PF05593.14 KFM71252.1 - 2.1e-11 44.0 12.0 0.22 12.1 0.2 9.5 9 2 2 11 11 11 3 RHS Repeat NHL PF01436.21 KFM71252.1 - 3.5e-06 26.8 0.0 2.2 8.5 0.0 5.0 5 0 0 5 5 5 2 NHL repeat EGF PF00008.27 KFM71252.1 - 0.00081 19.6 4.4 0.00081 19.6 4.4 9.0 7 1 1 8 8 8 3 EGF-like domain CarboxypepD_reg PF13620.6 KFM71252.1 - 0.0049 17.1 0.1 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain EGF_Tenascin PF18720.1 KFM71252.1 - 0.038 14.0 114.6 0.016 15.3 10.0 9.6 9 0 0 9 9 9 0 Tenascin EGF domain RHS PF03527.14 KFM71252.1 - 0.053 13.3 0.0 0.21 11.4 0.0 2.1 1 0 0 1 1 1 0 RHS protein HTH_Tnp_Tc3_2 PF01498.18 KFM71253.1 - 3.9e-16 59.1 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71253.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71253.1 - 3.2e-07 30.0 1.6 7.6e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71253.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71253.1 - 0.028 14.5 0.4 0.098 12.8 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM71253.1 - 3 8.5 15.6 0.13 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71254.1 - 2.4e-16 59.7 2.2 7e-16 58.2 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71254.1 - 6.3e-15 55.2 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71254.1 - 3.3e-07 29.9 1.6 8.4e-07 28.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71254.1 - 0.0033 17.2 0.5 0.009 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71254.1 - 0.037 14.2 0.4 0.11 12.7 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Fea1 PF07692.11 KFM71254.1 - 0.12 11.4 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein HTH_32 PF13565.6 KFM71254.1 - 3.4 8.3 15.6 0.15 12.7 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain EGF PF00008.27 KFM71256.1 - 1.8e-16 60.1 74.5 2.5e-07 30.9 7.6 7.3 7 2 0 7 7 7 4 EGF-like domain hEGF PF12661.7 KFM71256.1 - 2.6e-06 27.9 20.4 3.8e-05 24.1 8.3 8.0 10 0 0 10 10 10 4 Human growth factor-like EGF EGF_2 PF07974.13 KFM71256.1 - 0.0076 16.6 15.7 0.0076 16.6 15.7 7.4 5 1 2 7 7 7 4 EGF-like domain EGF_3 PF12947.7 KFM71256.1 - 4.5 7.6 63.9 0.89 9.8 1.1 6.4 4 2 1 5 5 5 0 EGF domain I-set PF07679.16 KFM71257.1 - 0.00014 21.9 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFM71257.1 - 0.00055 20.1 0.0 0.00067 19.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFM71257.1 - 0.00082 19.5 0.0 0.00094 19.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM71257.1 - 0.0027 17.7 0.0 0.0035 17.4 0.0 1.2 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 KFM71257.1 - 0.027 15.1 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 KFM71257.1 - 0.055 13.8 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Ig_6 PF18452.1 KFM71257.1 - 0.19 11.3 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFM71258.1 - 0.005 17.4 0.0 0.008 16.8 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM71258.1 - 0.008 16.2 0.1 0.022 14.8 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain FAF PF11250.8 KFM71258.1 - 0.084 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Fantastic Four meristem regulator Ig_2 PF13895.6 KFM71258.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.3 1 1 0 1 1 1 0 Immunoglobulin domain Zona_pellucida PF00100.23 KFM71259.1 - 2.1e-17 63.8 0.5 2.8e-17 63.4 0.5 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF4094 PF13334.6 KFM71259.1 - 0.35 11.3 0.9 2.9 8.4 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) HTH_Tnp_Tc3_2 PF01498.18 KFM71260.1 - 2e-15 56.8 1.4 4.1e-15 55.8 1.4 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71260.1 - 7.6e-05 23.2 6.4 0.0002 21.9 1.3 2.4 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM71260.1 - 0.00035 20.4 0.1 0.025 14.4 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_3 PF01381.22 KFM71260.1 - 0.0031 17.5 0.1 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix PAX PF00292.18 KFM71260.1 - 0.0032 17.4 0.0 0.0068 16.3 0.0 1.6 1 1 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFM71260.1 - 0.0034 17.1 0.1 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM71260.1 - 0.0066 16.4 0.4 0.023 14.7 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM71260.1 - 0.0098 15.4 0.2 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KFM71260.1 - 0.023 14.8 0.8 0.046 13.9 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_33 PF13592.6 KFM71260.1 - 0.078 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM71261.1 - 2.7e-16 59.5 2.2 4.9e-16 58.7 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71261.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71262.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71262.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71262.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71262.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71262.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71263.1 - 4.7e-16 58.8 3.5 5.6e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71263.1 - 6.1e-10 39.0 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71263.1 - 2.3e-07 30.5 0.2 6.9e-07 28.9 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71263.1 - 0.0024 17.6 0.6 0.0074 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain ASC PF00858.24 KFM71264.1 - 1.4e-05 24.2 0.1 1.4e-05 24.2 0.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Y_phosphatase PF00102.27 KFM71265.1 - 1.7e-52 178.4 0.0 2e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 KFM71266.1 - 2.5e-27 96.0 0.9 2.7e-27 95.9 0.9 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 KFM71268.1 - 0.0044 17.3 0.0 1.2 9.6 0.0 3.6 4 0 0 4 4 4 1 Fibronectin type III domain fn3 PF00041.21 KFM71269.1 - 1.3e-08 35.1 0.0 1.6e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM71269.1 - 0.0012 19.4 0.0 0.0053 17.3 0.0 1.8 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain ChitinaseA_N PF08329.10 KFM71269.1 - 0.091 12.4 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Chitinase A, N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM71271.1 - 2e-16 60.0 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71271.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM71272.1 - 7.5e-16 58.2 0.0 5.9e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71272.1 - 7.5e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71272.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71272.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71272.1 - 0.016 15.3 0.1 0.066 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71272.1 - 0.036 14.1 2.6 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DDT PF02791.17 KFM71274.1 - 0.053 13.8 0.0 0.071 13.4 0.0 1.3 1 1 0 1 1 1 0 DDT domain Pkinase PF00069.25 KFM71276.1 - 4.3e-72 242.6 0.0 5.6e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM71276.1 - 4.5e-35 121.2 0.0 6.4e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM71276.1 - 2.8e-08 33.4 0.0 4.3e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like POR PF01558.18 KFM71276.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase HTH_Tnp_Tc3_2 PF01498.18 KFM71279.1 - 2.2e-16 59.8 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71279.1 - 9.8e-14 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM71280.1 - 3.7e-13 49.5 0.0 4.9e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 KFM71281.1 - 8.1e-32 110.5 0.5 1.5e-31 109.7 0.2 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 KFM71281.1 - 2.5e-05 24.1 0.1 5.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease RdRP PF05183.12 KFM71282.1 - 7.5e-22 77.7 0.4 7.5e-22 77.7 0.4 1.4 2 0 0 2 2 2 1 RNA dependent RNA polymerase GAS PF13851.6 KFM71282.1 - 0.012 15.0 11.3 0.016 14.6 11.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Baculo_p24 PF05073.12 KFM71282.1 - 0.019 14.7 2.3 0.034 13.9 2.3 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein DUF1657 PF07870.11 KFM71282.1 - 0.024 14.5 0.5 0.061 13.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) DUF2968 PF11180.8 KFM71282.1 - 0.042 13.5 4.1 0.061 13.0 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Cor1 PF04803.12 KFM71282.1 - 0.12 12.5 12.9 0.062 13.5 1.5 2.7 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF1640 PF07798.11 KFM71282.1 - 0.28 11.2 10.1 0.79 9.7 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) CENP-B_N PF04218.13 KFM71282.1 - 0.5 10.0 3.1 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain YabA PF06156.13 KFM71282.1 - 7.4 7.3 10.9 4.6 7.9 2.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA RVT_1 PF00078.27 KFM71284.1 - 6.4e-08 32.4 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFM71285.1 - 1.5e-35 122.7 0.0 3.4e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1759 PF03564.15 KFM71285.1 - 1e-27 96.9 0.0 3.4e-27 95.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Integrase_H2C2 PF17921.1 KFM71285.1 - 1.7e-09 37.6 1.4 1.7e-09 37.6 1.4 2.9 4 0 0 4 4 4 1 Integrase zinc binding domain DUF5641 PF18701.1 KFM71285.1 - 8.4e-05 22.7 1.4 8.4e-05 22.7 1.4 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5641) zf-H2C2 PF09337.10 KFM71285.1 - 0.27 11.5 2.1 0.58 10.4 2.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM71286.1 - 3.1e-16 59.4 2.2 1e-15 57.7 2.2 2.0 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71286.1 - 2.9e-13 49.8 0.0 5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71286.1 - 5e-07 29.4 1.6 1.2e-06 28.2 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71286.1 - 0.0046 16.7 0.5 0.013 15.3 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain RdRP PF05183.12 KFM71287.1 - 3.2e-162 541.2 0.0 4.1e-162 540.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase FERM_f0 PF16511.5 KFM71287.1 - 0.043 14.1 0.2 0.22 11.8 0.1 2.3 3 0 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM Peptidase_A17 PF05380.13 KFM71288.1 - 5.3e-56 189.1 0.0 1.2e-55 188.0 0.0 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF5641 PF18701.1 KFM71288.1 - 8.4e-26 90.0 1.6 2.6e-25 88.4 1.6 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1758 PF05585.12 KFM71288.1 - 5.4e-13 49.0 0.8 1.3e-12 47.8 0.8 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) rve PF00665.26 KFM71288.1 - 5.9e-09 36.1 0.0 3.4e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM71288.1 - 2.9e-07 30.5 0.6 1.4e-06 28.3 0.6 2.3 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 KFM71288.1 - 3.3e-07 30.1 0.0 7.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFM71288.1 - 0.054 13.5 0.0 0.32 11.1 0.0 2.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 KFM71288.1 - 0.056 13.7 0.3 0.18 12.1 0.3 1.9 1 0 0 1 1 1 0 H2C2 zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM71289.1 - 4.6e-17 62.0 1.6 1.3e-15 57.4 2.2 2.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71289.1 - 8.1e-13 48.4 0.0 2.1e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71289.1 - 3.3e-07 30.0 0.4 1.4e-06 28.0 0.2 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain Apolipoprotein PF01442.18 KFM71289.1 - 0.0016 18.4 9.1 0.0038 17.1 9.1 1.6 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain HTH_23 PF13384.6 KFM71289.1 - 0.0046 16.7 0.5 0.015 15.1 0.5 1.9 1 0 0 1 1 1 1 Homeodomain-like domain Rab5-bind PF09311.11 KFM71289.1 - 0.017 14.5 12.8 0.032 13.6 12.8 1.3 1 0 0 1 1 1 0 Rabaptin-like protein Exonuc_VII_L PF02601.15 KFM71289.1 - 0.039 13.5 3.0 0.074 12.6 3.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4843 PF16132.5 KFM71289.1 - 0.043 13.4 3.9 0.08 12.5 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4843) HTH_28 PF13518.6 KFM71289.1 - 0.064 13.4 0.5 0.19 11.9 0.5 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain FapA PF03961.13 KFM71289.1 - 0.23 10.1 10.2 0.32 9.6 10.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Peptidase_S64 PF08192.11 KFM71289.1 - 0.37 9.2 6.1 0.63 8.5 6.1 1.3 1 0 0 1 1 1 0 Peptidase family S64 Fib_alpha PF08702.10 KFM71289.1 - 0.41 10.8 15.6 0.22 11.7 12.4 2.1 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFM71289.1 - 0.54 10.3 13.6 4.2 7.4 12.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Z1 PF10593.9 KFM71289.1 - 2.3 7.7 7.1 4.7 6.7 7.1 1.5 1 0 0 1 1 1 0 Z1 domain OmpH PF03938.14 KFM71289.1 - 2.6 8.4 17.5 4.7 7.6 17.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1690 PF07956.11 KFM71289.1 - 2.7 8.4 16.3 2.9 8.3 2.1 2.4 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) NPV_P10 PF05531.12 KFM71289.1 - 3.3 8.2 7.7 16 6.1 1.3 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 KFM71289.1 - 3.5 7.9 6.2 20 5.5 0.3 3.2 2 1 1 3 3 3 0 Haemolysin XhlA PIN_8 PF18476.1 KFM71289.1 - 4.6 7.0 10.7 8.2 6.2 10.7 1.4 1 0 0 1 1 1 0 PIN like domain Phage_GPO PF05929.11 KFM71289.1 - 6.4 6.3 13.6 33 4.0 13.8 1.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HTH_32 PF13565.6 KFM71289.1 - 7.4 7.3 15.6 0.26 11.9 1.9 3.5 2 1 1 3 3 2 0 Homeodomain-like domain Bacillus_HBL PF05791.11 KFM71289.1 - 9.9 6.0 8.7 6.2 6.6 2.1 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Tup_N PF08581.10 KFM71291.1 - 0.0045 17.3 1.8 0.0045 17.3 1.8 3.2 4 0 0 4 4 4 1 Tup N-terminal SASP PF00269.20 KFM71291.1 - 0.0092 16.0 1.3 0.026 14.5 1.3 1.8 1 0 0 1 1 1 1 Small, acid-soluble spore proteins, alpha/beta type Mo25 PF08569.11 KFM71291.1 - 0.2 11.0 2.4 0.3 10.4 2.4 1.3 1 0 0 1 1 1 0 Mo25-like Mto2_bdg PF12808.7 KFM71291.1 - 0.42 10.9 9.1 0.15 12.4 4.9 2.3 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF883 PF05957.13 KFM71291.1 - 1.4 9.5 5.6 2.4 8.8 4.5 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Paramyxo_ncap PF00973.19 KFM71291.1 - 2.1 7.1 8.8 3.3 6.5 8.8 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Rotamase PF00639.21 KFM71291.1 - 2.8 9.0 10.3 1.8 9.6 4.8 3.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Spc7 PF08317.11 KFM71291.1 - 6.1 5.6 22.5 1.8 7.4 17.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Rotamase_3 PF13616.6 KFM71291.1 - 6.6 7.3 7.9 1.8 9.2 3.4 2.3 2 1 0 2 2 2 0 PPIC-type PPIASE domain RdRP PF05183.12 KFM71292.1 - 3e-159 531.4 0.0 3.7e-159 531.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Methyltransf_16 PF10294.9 KFM71293.1 - 4.9e-38 130.6 0.0 6.2e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KFM71293.1 - 0.0023 17.4 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFM71293.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Neurensin PF14927.6 KFM71294.1 - 3.1e-28 98.1 0.0 4.1e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Neurensin DUF3784 PF12650.7 KFM71294.1 - 0.018 15.2 0.9 1.8 8.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) TMEM100 PF16311.5 KFM71294.1 - 0.31 10.6 0.8 6 6.5 0.0 2.5 3 0 0 3 3 3 0 Transmembrane protein 100 SelR PF01641.18 KFM71295.1 - 1e-18 67.6 0.7 1.2e-18 67.4 0.7 1.0 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.8 KFM71295.1 - 0.019 15.2 0.4 0.044 14.0 0.4 1.5 1 1 1 2 2 2 0 C-terminal domain of RIG-I Yippee-Mis18 PF03226.14 KFM71295.1 - 0.022 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF983 PF06170.12 KFM71295.1 - 0.062 13.7 0.4 0.77 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zinc_ribbon_2 PF13240.6 KFM71295.1 - 0.34 10.7 4.2 8.2 6.3 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain HTH_Tnp_Tc3_2 PF01498.18 KFM71296.1 - 2.3e-16 59.8 2.2 6.8e-16 58.3 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71296.1 - 1.6e-13 50.6 0.0 2.8e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71296.1 - 3.5e-07 29.9 1.6 8.1e-07 28.7 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71296.1 - 0.0032 17.2 0.5 0.0088 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Ank_2 PF12796.7 KFM71297.1 - 4.7e-55 184.1 4.6 3.6e-10 40.3 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM71297.1 - 1.6e-43 146.6 9.2 6.4e-08 33.0 0.0 10.0 7 2 2 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM71297.1 - 7.3e-40 134.5 10.2 5.4e-08 33.0 0.0 9.5 7 2 2 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM71297.1 - 3.9e-32 106.7 9.3 0.00051 20.3 0.0 11.9 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 KFM71297.1 - 2.8e-30 103.4 13.4 0.00059 20.2 0.0 10.5 10 0 0 10 10 10 7 Ankyrin repeat Dpy-30 PF05186.13 KFM71297.1 - 3.6e-12 45.8 0.1 9.1e-12 44.5 0.1 1.7 1 0 0 1 1 1 1 Dpy-30 motif GATase_7 PF13537.6 KFM71297.1 - 4.4e-08 33.1 3.0 8.8 6.3 0.0 8.1 8 1 1 9 9 9 2 Glutamine amidotransferase domain DUF587 PF04532.12 KFM71297.1 - 0.0024 17.2 0.1 0.79 9.0 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF587) HTH_Tnp_Tc3_2 PF01498.18 KFM71298.1 - 4.3e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71298.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71298.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71298.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71298.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Pkinase_Tyr PF07714.17 KFM71299.1 - 2.9e-44 151.3 0.0 5.5e-44 150.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFM71299.1 - 2.5e-29 102.4 0.0 4.9e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFM71299.1 - 0.0063 15.9 0.2 0.2 10.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFM71299.1 - 0.012 15.0 0.5 0.022 14.1 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4371 PF14291.6 KFM71300.1 - 2.2e-30 106.1 0.5 4.2e-30 105.1 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM71300.1 - 2.3e-08 33.7 0.2 8.6e-08 31.9 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM71300.1 - 0.024 13.6 7.4 0.042 12.8 0.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MAT1 PF06391.13 KFM71300.1 - 1.5 8.6 7.4 2 8.2 2.0 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Exonuc_VII_L PF02601.15 KFM71300.1 - 4.8 6.6 6.9 7.6 6.0 0.9 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4371 PF14291.6 KFM71301.1 - 3e-30 105.6 0.5 5.9e-30 104.7 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM71301.1 - 2e-09 37.1 0.2 7.8e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM71301.1 - 1.3 8.0 15.0 0.054 12.5 0.4 3.1 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 KFM71301.1 - 7.1 6.1 9.7 6.2 6.3 1.1 3.0 3 0 0 3 3 3 0 Exonuclease VII, large subunit RhoGEF PF00621.20 KFM71302.1 - 2.9e-28 99.4 0.4 7.4e-28 98.0 0.4 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 KFM71302.1 - 7.4e-25 87.5 1.4 5.3e-13 49.4 0.1 3.0 3 0 0 3 3 3 2 PH domain FERM_C PF09380.10 KFM71302.1 - 1.4e-22 79.9 0.7 3e-22 78.8 0.7 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFM71302.1 - 9.2e-16 57.7 8.5 2.6e-15 56.2 8.5 1.9 1 0 0 1 1 1 1 FERM adjacent (FA) PH_13 PF16652.5 KFM71302.1 - 1.3e-07 31.5 2.4 0.017 15.0 0.2 3.8 3 1 0 3 3 3 2 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFM71302.1 - 0.00013 21.9 0.0 0.00038 20.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFM71302.1 - 0.035 14.5 1.5 0.17 12.3 1.0 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain FERM_M PF00373.18 KFM71302.1 - 0.088 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 FERM central domain PH_11 PF15413.6 KFM71302.1 - 0.91 10.0 10.3 0.72 10.3 1.5 4.0 3 1 0 3 3 3 0 Pleckstrin homology domain FERM_N PF09379.10 KFM71303.1 - 1.6e-16 60.0 0.1 2.3e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 FERM N-terminal domain SNF5 PF04855.12 KFM71304.1 - 6.7e-57 193.0 0.5 4.6e-53 180.5 0.5 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF3685 PF12452.8 KFM71305.1 - 0.03 14.0 0.6 0.034 13.9 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) APG9 PF04109.16 KFM71306.1 - 1.8e-08 33.9 0.1 1.8e-08 33.9 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 APG9 PF04109.16 KFM71307.1 - 1.2e-69 235.6 0.3 1.4e-69 235.4 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 APG9 PF04109.16 KFM71308.1 - 3.3e-33 115.4 0.8 4.1e-33 115.1 0.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 PHR PF08005.12 KFM71310.1 - 0.0091 16.7 0.1 0.019 15.6 0.0 1.5 1 1 0 1 1 1 1 PHR domain tRNA-synt_2c PF01411.19 KFM71311.1 - 1.1e-13 50.6 0.1 1.3e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA-synt_2c PF01411.19 KFM71312.1 - 4.2e-16 58.6 0.2 4.4e-16 58.5 0.2 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA-synt_2c PF01411.19 KFM71313.1 - 4.8e-21 74.9 0.0 5.3e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA-synt_2c PF01411.19 KFM71314.1 - 1.2e-09 37.2 0.6 4.5e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFM71314.1 - 7.9e-06 25.9 0.1 2e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF948 PF06103.11 KFM71314.1 - 0.0049 17.1 0.4 0.013 15.7 0.1 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Vip3A_N PF12495.8 KFM71314.1 - 0.17 11.8 0.8 0.36 10.7 0.8 1.5 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal tRNA_SAD PF07973.14 KFM71315.1 - 3.9e-07 30.1 0.5 8.3e-07 29.0 0.1 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain NTP_transf_2 PF01909.23 KFM71315.1 - 0.094 13.0 0.1 0.17 12.2 0.0 1.7 2 1 0 2 2 2 0 Nucleotidyltransferase domain Neur_chan_memb PF02932.16 KFM71317.1 - 3.8e-12 46.8 0.0 6.6e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Prominin PF05478.11 KFM71317.1 - 0.0017 16.4 0.1 0.0022 16.0 0.1 1.1 1 0 0 1 1 1 1 Prominin Neur_chan_LBD PF02931.23 KFM71318.1 - 4.9e-73 245.1 3.0 5.8e-73 244.9 3.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM71318.1 - 1.6e-20 74.2 4.0 1.6e-20 74.2 4.0 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region NYN PF01936.18 KFM71318.1 - 0.039 14.4 0.0 0.085 13.3 0.0 1.6 1 1 0 1 1 1 0 NYN domain HTH_Tnp_Tc3_2 PF01498.18 KFM71319.1 - 4.6e-16 58.8 3.7 4.9e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71319.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71319.1 - 2.7e-07 30.2 1.3 9.3e-07 28.5 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71319.1 - 0.01 15.6 0.7 0.03 14.1 0.7 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM71319.1 - 2.2 9.0 16.1 0.11 13.1 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM71321.1 - 0.002 17.9 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Aldo_ket_red PF00248.21 KFM71322.1 - 4.2e-11 42.6 0.1 4.5e-11 42.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase_Tyr PF07714.17 KFM71323.1 - 1.4e-87 293.3 0.0 1.8e-87 292.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM71323.1 - 8.6e-39 133.5 0.0 1.2e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GF_recep_IV PF14843.6 KFM71323.1 - 0.00041 20.2 42.1 0.0019 18.0 19.1 3.3 1 1 0 2 2 2 2 Growth factor receptor domain IV Haspin_kinase PF12330.8 KFM71323.1 - 0.0035 16.3 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM71323.1 - 0.0086 15.4 0.0 0.02 14.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFM71323.1 - 0.048 13.6 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Furin-like PF00757.20 KFM71323.1 - 6 6.7 45.1 1.9 8.4 11.6 3.3 1 1 1 3 3 3 0 Furin-like cysteine rich region Recep_L_domain PF01030.24 KFM71324.1 - 5.1e-41 139.3 0.0 2.1e-25 89.0 0.0 2.2 2 0 0 2 2 2 2 Receptor L domain Furin-like PF00757.20 KFM71324.1 - 6.3e-26 91.0 40.4 1.2e-25 90.2 40.4 1.4 1 0 0 1 1 1 1 Furin-like cysteine rich region GF_recep_IV PF14843.6 KFM71324.1 - 6.9e-06 25.9 45.9 0.032 14.0 21.9 4.7 1 1 2 3 3 3 3 Growth factor receptor domain IV Sugar_tr PF00083.24 KFM71326.1 - 1.9e-15 56.7 2.2 2.1e-15 56.5 2.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4191 PF13829.6 KFM71326.1 - 0.017 14.5 0.1 0.021 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PCMT PF01135.19 KFM71327.1 - 2e-24 86.6 0.0 3.4e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 KFM71327.1 - 0.00037 20.8 8.2 0.16 12.4 1.4 2.5 2 0 0 2 2 2 2 SOCS box GCD14 PF08704.10 KFM71327.1 - 0.0015 18.3 3.7 0.0085 15.8 0.0 3.0 2 1 1 3 3 3 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KFM71327.1 - 0.033 14.0 0.0 0.079 12.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KFM71327.1 - 0.035 13.6 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Fibrinogen_C PF00147.18 KFM71328.1 - 3.7e-75 252.5 4.4 5e-75 252.1 4.4 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CHDCT2 PF08074.11 KFM71328.1 - 0.6 10.3 2.8 0.88 9.7 2.8 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain HECT PF00632.25 KFM71329.1 - 7.2e-84 281.9 0.8 1.3e-83 281.1 0.8 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WWE PF02825.20 KFM71329.1 - 9.4e-16 58.2 0.9 3.2e-15 56.5 0.9 2.0 1 0 0 1 1 1 1 WWE domain HEAT_2 PF13646.6 KFM71329.1 - 0.042 14.2 0.2 0.39 11.2 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats Spore_permease PF03845.13 KFM71329.1 - 0.12 11.2 0.1 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 Spore germination protein S-antigen PF05756.11 KFM71329.1 - 0.64 10.4 2.8 14 6.1 0.2 3.0 2 0 0 2 2 2 0 S-antigen protein DDE_Tnp_1_7 PF13843.6 KFM71330.1 - 3.7e-18 66.0 0.0 4.7e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 C1_1 PF00130.22 KFM71330.1 - 0.13 12.2 7.0 0.47 10.4 7.0 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFM71330.1 - 0.45 10.9 7.6 0.15 12.4 4.4 1.9 2 0 0 2 2 2 0 C1 domain PFK PF00365.20 KFM71331.1 - 4.3e-157 521.7 0.4 5.6e-94 314.6 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase HTH_Tnp_Tc3_2 PF01498.18 KFM71332.1 - 1.1e-08 35.2 1.7 2.2e-08 34.2 1.7 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71332.1 - 0.00026 20.8 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.22 KFM71333.1 - 2.4e-12 46.5 0.0 3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM71333.1 - 0.028 14.0 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_3 PF13358.6 KFM71334.1 - 1.3e-07 31.5 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease THAP PF05485.12 KFM71334.1 - 0.034 15.1 0.0 0.08 13.9 0.0 1.7 1 1 0 1 1 1 0 THAP domain pRN1_helical PF13010.6 KFM71334.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Primase helical domain DDE_1 PF03184.19 KFM71335.1 - 1.1e-40 139.2 0.7 1.7e-40 138.5 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM71335.1 - 7.8e-14 51.5 0.2 2.3e-13 50.0 0.2 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM71335.1 - 1.1e-05 25.0 2.7 3.4e-05 23.4 2.7 1.9 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFM71335.1 - 0.014 15.2 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.16 KFM71335.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Ada3 PF10198.9 KFM71335.1 - 0.12 12.5 0.9 0.29 11.3 0.3 1.9 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 Med13_N PF11597.8 KFM71336.1 - 5.5e-17 62.1 0.1 7.8e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 KFM71337.1 - 1.7e-107 359.5 1.4 1.7e-107 359.5 1.4 6.3 5 1 1 6 6 6 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 KFM71337.1 - 2.1e-73 247.2 0.3 2.1e-73 247.2 0.3 3.5 2 1 1 3 3 3 1 MID domain of medPIWI Condensin2nSMC PF12422.8 KFM71337.1 - 0.063 13.5 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DDE_3 PF13358.6 KFM71338.1 - 2.7e-13 49.9 0.0 3.2e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PH PF00169.29 KFM71339.1 - 1.1e-23 83.7 0.1 1.7e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFM71339.1 - 6.3e-06 26.4 0.5 1.3e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KFM71339.1 - 0.00015 22.2 1.3 0.0022 18.4 1.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFM71339.1 - 0.01 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.6 KFM71339.1 - 0.027 14.8 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_5 PF15405.6 KFM71339.1 - 0.035 14.2 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Bcr-Abl_Oligo PF09036.10 KFM71340.1 - 8.4e-06 25.7 0.5 1.8e-05 24.7 0.5 1.5 1 0 0 1 1 1 1 Bcr-Abl oncoprotein oligomerisation domain DNA_pol_B_2 PF03175.13 KFM71341.1 - 0.039 12.8 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DUF559 PF04480.12 KFM71341.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF559) HTH_Tnp_Tc3_2 PF01498.18 KFM71342.1 - 5.1e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71342.1 - 1.4e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71342.1 - 2.1e-07 30.6 1.2 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71342.1 - 0.003 17.3 0.6 0.0078 16.0 0.6 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71342.1 - 0.033 14.3 0.4 0.093 12.9 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM71342.1 - 2.5 8.8 15.1 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Vps55 PF04133.14 KFM71344.1 - 4.9e-33 113.6 2.3 5.4e-33 113.4 2.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 HTH_Tnp_Tc3_2 PF01498.18 KFM71345.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71345.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol_phi PF04931.13 KFM71348.1 - 0.00016 19.9 0.3 0.00032 19.0 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase phi DNA_pol_phi PF04931.13 KFM71349.1 - 1.9e-116 390.1 16.9 1.9e-116 390.1 16.9 1.3 2 0 0 2 2 2 1 DNA polymerase phi Ntox35 PF15534.6 KFM71349.1 - 1 9.9 3.6 23 5.5 0.3 3.1 3 0 0 3 3 3 0 Bacterial toxin 35 DDE_3 PF13358.6 KFM71350.1 - 1.4e-13 50.9 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71350.1 - 9.8e-08 32.1 0.8 3.5e-06 27.2 1.1 2.5 2 1 0 2 2 2 1 Transposase APA3_viroporin PF11289.8 KFM71351.1 - 0.095 12.2 0.9 0.1 12.1 0.9 1.0 1 0 0 1 1 1 0 Coronavirus accessory protein 3a HTH_Tnp_Tc3_2 PF01498.18 KFM71352.1 - 7.3e-05 22.9 0.2 0.00011 22.4 0.2 1.2 1 0 0 1 1 1 1 Transposase DNA_ligase_A_M PF01068.21 KFM71353.1 - 4.4e-64 215.9 1.2 7.9e-64 215.1 1.2 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFM71353.1 - 5.9e-44 150.4 0.2 1.5e-43 149.1 0.2 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KFM71353.1 - 5e-25 88.0 0.0 1.8e-24 86.2 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KFM71353.1 - 7e-06 26.4 0.5 1.6e-05 25.3 0.5 1.6 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 KFM71353.1 - 0.0011 18.8 2.4 0.086 12.7 0.3 3.1 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain DDE_Tnp_4 PF13359.6 KFM71354.1 - 2.8e-21 75.8 0.0 5.2e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM71354.1 - 1.1e-10 41.5 0.0 1.8e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein zf-met PF12874.7 KFM71355.1 - 2.1e-23 82.0 24.7 9.5e-05 22.7 0.2 5.5 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM71355.1 - 2.2e-18 66.0 19.2 0.0008 19.6 0.1 5.5 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM71355.1 - 8.2e-13 48.6 19.7 0.031 14.6 0.4 5.2 4 1 1 5 5 5 5 C2H2 type zinc-finger (2 copies) DUF3449 PF11931.8 KFM71355.1 - 2e-08 34.2 7.5 0.14 12.0 0.0 5.3 4 1 2 6 6 6 3 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.6 KFM71355.1 - 4.6e-08 33.2 20.9 0.24 12.3 1.7 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM71355.1 - 6.5e-06 26.3 25.2 0.82 10.3 0.1 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type DUF629 PF04780.12 KFM71355.1 - 0.00019 20.1 17.5 0.67 8.4 0.1 5.0 3 1 2 5 5 5 4 Protein of unknown function (DUF629) zf-DBF PF07535.12 KFM71355.1 - 0.0013 18.8 22.2 1.2 9.3 0.2 5.5 5 0 0 5 5 5 3 DBF zinc finger DUF4150 PF13665.6 KFM71355.1 - 0.0019 18.3 0.2 1.1 9.5 0.0 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4150) VATC PF18716.1 KFM71355.1 - 0.053 13.4 19.6 1.6 8.6 0.3 4.8 5 0 0 5 5 5 0 Vms1-associating treble clef domain zf-Di19 PF05605.12 KFM71355.1 - 0.064 13.6 1.5 0.064 13.6 1.5 3.8 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.22 KFM71355.1 - 1.1 9.2 13.2 8.6 6.3 0.3 4.8 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KFM71355.1 - 3.6 7.5 13.8 0.096 12.6 2.0 3.3 2 2 1 4 4 4 0 Putative zinc-RING and/or ribbon DUF5402 PF17393.2 KFM71355.1 - 4.1 7.4 6.1 21 5.1 0.0 3.4 3 1 1 4 4 4 0 Family of unknown function (DUF5402) Fer4_16 PF13484.6 KFM71355.1 - 5.1 8.1 10.6 22 6.1 0.2 4.4 4 1 0 4 4 4 0 4Fe-4S double cluster binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM71356.1 - 1.9e-19 69.7 3.6 5.6e-19 68.2 2.1 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71356.1 - 4.4e-16 59.0 0.0 2.2e-15 56.7 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM71356.1 - 2.1e-07 30.9 0.4 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM71356.1 - 3.5e-07 30.7 2.0 3.5e-07 30.7 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71356.1 - 9.3e-07 28.9 2.3 7.5e-05 22.8 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71356.1 - 1.8e-06 27.5 3.4 2.5e-05 23.9 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM71356.1 - 2.8e-06 27.2 0.7 3.9e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM71356.1 - 0.00011 22.0 0.6 0.0017 18.2 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM71356.1 - 0.001 19.0 0.3 0.016 15.2 0.0 2.4 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM71356.1 - 0.021 14.5 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM71356.1 - 0.051 13.6 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM71356.1 - 0.088 13.0 0.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM71356.1 - 0.15 11.6 0.2 0.8 9.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM71356.1 - 0.16 12.0 0.0 29 4.8 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM71356.1 - 0.29 11.0 3.9 1.4 8.7 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM71356.1 - 1.1 8.7 3.6 7 6.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.6 KFM71357.1 - 2.7e-16 59.6 0.1 3e-15 56.3 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71357.1 - 1.4e-10 41.2 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase Transposase_1 PF01359.18 KFM71358.1 - 3.1e-12 46.1 0.0 3.9e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Transposase (partial DDE domain) TMEM100 PF16311.5 KFM71358.1 - 0.049 13.2 0.3 0.069 12.7 0.2 1.3 1 1 0 1 1 1 0 Transmembrane protein 100 Lig_chan PF00060.26 KFM71359.1 - 1.8e-09 37.6 5.2 2.3e-09 37.3 5.2 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Nramp PF01566.18 KFM71359.1 - 0.016 14.2 2.3 0.028 13.4 0.2 1.8 1 1 1 2 2 2 0 Natural resistance-associated macrophage protein DUF21 PF01595.20 KFM71359.1 - 0.028 14.1 1.1 0.12 12.0 0.2 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Iron_traffic PF04362.14 KFM71359.1 - 0.069 12.9 0.4 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking EI24 PF07264.11 KFM71359.1 - 1.6 9.0 10.4 53 4.0 11.8 1.9 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) ApoL PF05461.11 KFM71360.1 - 0.048 13.0 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein L Vps35 PF03635.17 KFM71361.1 - 1.2e-148 496.8 12.3 1.5e-148 496.5 12.3 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Vps62 PF06101.11 KFM71361.1 - 0.00074 17.9 1.4 0.035 12.4 0.2 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 DUF745 PF05335.13 KFM71361.1 - 0.02 14.6 2.6 0.041 13.6 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1943 PF09172.11 KFM71361.1 - 0.033 13.5 1.0 0.045 13.0 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Cauli_AT PF03233.13 KFM71361.1 - 0.13 12.2 3.9 0.12 12.3 1.3 2.3 2 0 0 2 2 2 0 Aphid transmission protein LSM PF01423.22 KFM71362.1 - 5e-12 45.3 3.2 6.1e-12 45.1 3.2 1.1 1 0 0 1 1 1 1 LSM domain HDA2-3 PF11496.8 KFM71362.1 - 0.075 12.2 0.3 0.078 12.1 0.3 1.1 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 SKA1 PF07160.12 KFM71363.1 - 0.00028 20.8 1.7 0.00032 20.6 1.7 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF3461 PF11944.8 KFM71363.1 - 0.024 14.8 0.7 0.047 13.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Rsd_AlgQ PF04353.13 KFM71363.1 - 0.031 14.2 0.6 0.76 9.7 0.1 2.1 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ SKA2 PF16740.5 KFM71363.1 - 0.16 11.8 4.9 5.1 6.9 0.4 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF643 PF04867.12 KFM71363.1 - 0.16 12.6 3.1 1.4 9.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF643) MarB PF13999.6 KFM71365.1 - 0.15 11.9 0.0 0.4 10.6 0.0 1.6 2 0 0 2 2 2 0 MarB protein TSP_1 PF00090.19 KFM71366.1 - 7e-19 67.8 150.3 3.6e-10 39.9 2.2 17.6 18 1 0 18 18 18 12 Thrombospondin type 1 domain DDE_3 PF13358.6 KFM71367.1 - 0.00029 20.6 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71368.1 - 2.2e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71368.1 - 9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease EPL1 PF10513.9 KFM71369.1 - 3.9e-11 43.6 2.7 4.4e-11 43.4 0.2 2.0 2 0 0 2 2 2 1 Enhancer of polycomb-like CAF1A PF12253.8 KFM71369.1 - 0.0036 17.4 0.1 0.0084 16.3 0.1 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A GH3 PF03321.13 KFM71369.1 - 0.025 13.4 0.1 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Keratin_matx PF04579.12 KFM71370.1 - 0.056 13.8 4.4 0.43 10.9 1.7 2.5 1 1 1 2 2 2 0 Keratin, high-sulphur matrix protein DUF1759 PF03564.15 KFM71372.1 - 1.9e-35 122.0 0.5 2.7e-35 121.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM71372.1 - 0.00024 20.9 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) I-set PF07679.16 KFM71373.1 - 1.1e-67 224.2 0.8 2.6e-16 59.4 0.0 5.5 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM71373.1 - 2.5e-61 204.2 8.4 3.7e-16 59.5 0.2 5.9 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.21 KFM71373.1 - 1.6e-48 162.9 2.1 2.9e-13 50.0 0.0 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.6 KFM71373.1 - 4.7e-38 129.4 6.0 4.5e-10 39.7 0.0 5.4 6 0 0 6 6 6 4 Immunoglobulin domain ig PF00047.25 KFM71373.1 - 1.1e-37 128.1 4.9 8.3e-11 41.9 0.0 5.4 7 0 0 7 7 6 4 Immunoglobulin domain Bravo_FIGEY PF13882.6 KFM71373.1 - 3.2e-23 82.9 3.9 7.6e-23 81.7 3.9 1.7 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 KFM71373.1 - 9.3e-23 80.5 13.6 0.0017 18.5 0.1 9.7 6 4 1 7 7 7 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM71373.1 - 1.4e-11 44.3 0.7 0.012 15.7 0.0 4.5 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM71373.1 - 1.5e-10 41.3 0.1 0.12 12.7 0.0 4.7 4 0 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM71373.1 - 3.4e-09 36.8 1.7 0.037 14.3 0.0 4.8 5 0 0 5 5 5 3 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFM71373.1 - 1.1e-07 32.1 0.6 0.033 14.6 0.0 4.5 4 0 0 4 4 4 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFM71373.1 - 1.4e-07 30.9 0.0 0.034 13.7 0.0 4.4 4 0 0 4 4 4 2 Immunoglobulin domain Herpes_gE PF02480.16 KFM71373.1 - 0.0026 16.6 0.1 4.5 5.9 0.0 3.6 3 1 0 4 4 4 2 Alphaherpesvirus glycoprotein E Pur_ac_phosph_N PF16656.5 KFM71373.1 - 0.0075 16.8 0.3 2.8 8.6 0.0 4.0 5 0 0 5 5 2 1 Purple acid Phosphatase, N-terminal domain Glyco_hydro_36C PF16874.5 KFM71373.1 - 0.11 13.0 0.0 0.48 11.0 0.0 2.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 C-terminal domain DDE_Tnp_4 PF13359.6 KFM71375.1 - 3.9e-36 124.1 0.0 5.1e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM71375.1 - 1.7e-09 37.6 0.0 6.6e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Plant transposon protein PAP_assoc PF03828.19 KFM71378.1 - 7.3e-15 54.9 0.0 1.8e-10 40.9 0.0 2.8 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFM71378.1 - 5e-06 26.7 0.0 1.2e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KFM71378.1 - 0.0023 18.0 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase CLIP1_ZNF PF16641.5 KFM71378.1 - 1.8 8.6 9.0 5 7.1 0.1 3.3 2 1 0 2 2 2 0 CLIP1 zinc knuckle zf-CCHC PF00098.23 KFM71378.1 - 6.4 7.0 16.9 0.29 11.3 2.0 3.0 3 0 0 3 3 3 0 Zinc knuckle EOS1 PF12326.8 KFM71380.1 - 5.5 6.9 6.4 2.2 8.2 3.6 1.7 2 0 0 2 2 2 0 N-glycosylation protein NTP_transf_2 PF01909.23 KFM71382.1 - 4.9e-05 23.6 0.0 9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KFM71382.1 - 0.00071 19.6 0.0 0.0022 18.1 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase DUF3128 PF11326.8 KFM71382.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Retrotran_gag_2 PF14223.6 KFM71383.1 - 0.022 14.5 0.2 0.022 14.5 0.2 1.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KFM71383.1 - 0.21 11.7 2.9 0.36 11.0 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle CLIP1_ZNF PF16641.5 KFM71384.1 - 0.013 15.4 1.1 0.02 14.8 1.1 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle LRR_8 PF13855.6 KFM71385.1 - 9.2e-14 51.0 9.7 1.9e-06 27.5 0.1 3.8 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM71385.1 - 3.4e-10 40.0 19.0 0.00031 21.1 2.7 5.2 2 2 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM71385.1 - 3e-06 27.0 6.2 1.6 9.6 1.0 5.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_5 PF13306.6 KFM71385.1 - 3.5e-06 27.0 4.0 4.5e-06 26.7 0.5 2.3 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM71385.1 - 0.00013 21.5 0.4 0.029 13.9 0.0 2.7 1 1 2 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 KFM71385.1 - 0.017 15.1 5.0 13 6.1 0.5 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRRNT PF01462.18 KFM71385.1 - 0.035 13.8 0.2 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain p450 PF00067.22 KFM71387.1 - 1.9e-63 214.8 0.2 2.1e-63 214.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ_CXXCXGXG PF00684.19 KFM71388.1 - 0.044 14.1 3.5 0.044 14.1 3.5 3.3 1 1 1 2 2 2 0 DnaJ central domain PfkB PF00294.24 KFM71389.1 - 1.4e-44 152.6 0.0 1.8e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF2118 PF09891.9 KFM71389.1 - 0.0036 17.3 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) HK PF02110.15 KFM71389.1 - 0.051 12.9 0.2 0.078 12.4 0.2 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family CUB PF00431.20 KFM71390.1 - 4.3e-80 265.2 0.2 2.1e-25 89.2 0.1 3.6 3 0 0 3 3 3 3 CUB domain Trypsin PF00089.26 KFM71390.1 - 2.4e-63 213.9 0.0 3.8e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin I-set PF07679.16 KFM71390.1 - 6.2e-18 64.7 0.0 5.6e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM71390.1 - 3.8e-15 56.2 0.0 2.6e-07 31.1 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM71390.1 - 1.6e-11 44.4 0.0 1.2e-05 25.5 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFM71390.1 - 1.7e-11 44.2 0.0 1.8e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFM71390.1 - 2.3e-06 27.1 0.0 0.037 13.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM71390.1 - 3.2e-06 27.3 0.0 0.0043 17.2 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM71390.1 - 0.0017 18.7 0.0 0.42 11.1 0.0 2.9 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM71390.1 - 0.0047 17.2 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain GST_C_3 PF14497.6 KFM71390.1 - 0.13 12.4 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MBOAT PF03062.19 KFM71392.1 - 9.9e-09 35.0 0.5 9.9e-09 35.0 0.5 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 KFM71393.1 - 0.00083 18.8 2.0 0.0011 18.4 2.0 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PET PF06297.14 KFM71395.1 - 2.2e-36 124.0 0.3 5.4e-36 122.8 0.3 1.7 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 KFM71395.1 - 6.6e-28 96.7 37.6 1.4e-11 44.4 8.5 3.8 4 0 0 4 4 4 3 LIM domain Vasculin PF15337.6 KFM71395.1 - 0.091 13.6 0.1 0.091 13.6 0.1 2.6 2 1 0 3 3 3 0 Vascular protein family Vasculin-like 1 Dehydrin PF00257.19 KFM71395.1 - 3.2 8.3 12.5 0.57 10.7 1.6 2.6 2 0 0 2 2 2 0 Dehydrin DUF2678 PF10856.8 KFM71396.1 - 1.2e-35 122.0 1.0 1.3e-35 121.9 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) DUF2417 PF10329.9 KFM71396.1 - 0.001 18.5 3.2 0.0015 18.0 3.2 1.3 1 1 0 1 1 1 1 Region of unknown function (DUF2417) CoA_binding_3 PF13727.6 KFM71396.1 - 2.9 7.9 4.7 0.86 9.6 0.4 1.8 1 1 1 2 2 2 0 CoA-binding domain LIN37 PF15306.6 KFM71397.1 - 2.5e-41 141.5 3.1 2.5e-41 141.5 3.1 1.9 1 1 1 2 2 2 1 LIN37 RabGAP-TBC PF00566.18 KFM71398.1 - 5.6e-49 166.7 0.1 5.6e-49 166.7 0.1 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4570 PF15134.6 KFM71398.1 - 0.14 12.1 2.8 0.36 10.9 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DDE_Tnp_IS1595 PF12762.7 KFM71399.1 - 1.5e-20 73.8 0.0 1.9e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KFM71399.1 - 0.005 16.4 0.0 0.0064 16.0 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family DDE_3 PF13358.6 KFM71399.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 DDE superfamily endonuclease MAAL_C PF07476.11 KFM71399.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Drf_GBD PF06371.13 KFM71400.1 - 0.045 13.3 0.1 0.045 13.3 0.1 1.0 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain EF-hand_1 PF00036.32 KFM71401.1 - 1.3e-18 65.0 4.6 6e-06 25.4 0.7 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFM71401.1 - 1.7e-15 55.6 2.6 2.3e-06 27.1 0.8 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFM71401.1 - 3.1e-15 56.4 0.2 7.2e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFM71401.1 - 2.9e-10 39.8 2.8 1.2e-05 25.1 0.0 3.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFM71401.1 - 6.8e-10 38.0 5.8 0.00014 21.2 0.8 3.5 3 0 0 3 3 3 2 EF hand DUF3741 PF12552.8 KFM71401.1 - 0.015 15.2 0.2 0.043 13.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) Caleosin PF05042.13 KFM71401.1 - 0.034 14.1 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Caleosin related protein SurA_N_2 PF13623.6 KFM71401.1 - 0.044 13.7 0.2 0.31 10.9 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain LXG PF04740.12 KFM71401.1 - 0.057 13.1 0.3 2 8.1 0.0 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily EF-hand_9 PF14658.6 KFM71401.1 - 0.074 13.4 0.0 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Ig_3 PF13927.6 KFM71402.1 - 0.0017 18.9 0.0 0.0024 18.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM71402.1 - 0.043 13.9 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain HTH_Tnp_Tc3_2 PF01498.18 KFM71403.1 - 7e-18 64.7 1.0 4.8e-16 58.8 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71403.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71404.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71404.1 - 7.6e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_H PF00075.24 KFM71405.1 - 0.0074 16.5 0.0 0.0074 16.5 0.0 1.1 1 0 0 1 1 1 1 RNase H SNN_linker PF09050.10 KFM71405.1 - 0.26 11.1 0.2 0.72 9.7 0.1 1.7 2 0 0 2 2 2 0 Stannin unstructured linker MTP18 PF10558.9 KFM71406.1 - 0.07 13.1 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) HTH_Tnp_Tc3_2 PF01498.18 KFM71407.1 - 8.7e-12 45.1 2.2 8.7e-12 45.1 2.2 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71407.1 - 6e-09 35.8 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM71407.1 - 0.0002 21.0 2.3 0.025 14.4 0.2 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.6 KFM71407.1 - 0.00031 21.3 3.1 0.00031 21.3 3.1 3.5 2 1 1 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 KFM71407.1 - 0.00073 19.1 0.5 0.0019 17.8 0.5 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.6 KFM71407.1 - 0.0062 16.3 1.5 0.0094 15.7 0.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Nterm_IS4 PF13006.7 KFM71407.1 - 0.087 13.0 0.8 0.81 9.9 0.0 2.6 2 1 1 3 3 3 0 Insertion element 4 transposase N-terminal HTH_29 PF13551.6 KFM71407.1 - 0.11 12.5 4.6 0.17 11.9 0.8 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 KFM71407.1 - 5.7 7.2 8.0 3.4 7.9 0.5 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain DDE_1 PF03184.19 KFM71408.1 - 2.9e-47 160.6 1.5 5.4e-47 159.7 1.5 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM71408.1 - 1.2e-11 44.5 0.0 3.2e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM71408.1 - 0.015 15.1 0.0 0.074 12.8 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease CENP-B_dimeris PF09026.10 KFM71408.1 - 2.4 8.6 9.7 0.28 11.6 2.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HTH_Tnp_Tc3_2 PF01498.18 KFM71409.1 - 5.2e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71409.1 - 5.3e-15 55.4 0.0 9.2e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71409.1 - 2.4e-08 33.6 1.6 6.8e-08 32.2 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71409.1 - 0.0077 16.0 0.7 0.022 14.6 0.7 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71409.1 - 0.012 15.7 0.5 0.036 14.2 0.5 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM71409.1 - 0.49 11.0 16.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Hexokinase_2 PF03727.16 KFM71410.1 - 6.4e-80 268.0 0.0 1.2e-79 267.2 0.0 1.4 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFM71410.1 - 4.2e-71 239.0 0.0 5.9e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase zf-RING_2 PF13639.6 KFM71411.1 - 6.1e-14 52.1 5.2 1.2e-13 51.1 5.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM71411.1 - 3.4e-11 42.8 5.5 8e-11 41.6 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM71411.1 - 1.5e-10 40.9 3.2 3.6e-10 39.7 3.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFM71411.1 - 5.4e-09 36.2 5.4 7.8e-09 35.7 3.9 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM71411.1 - 1.3e-08 34.5 3.9 3.2e-08 33.3 3.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM71411.1 - 1.1e-07 31.7 2.4 2.6e-07 30.5 2.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFM71411.1 - 3.4e-07 29.9 2.2 8.1e-07 28.7 2.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFM71411.1 - 6.3e-07 29.1 2.6 1.4e-06 28.1 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFM71411.1 - 8.6e-06 25.7 2.0 1.7e-05 24.8 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFM71411.1 - 0.00019 21.0 2.1 0.00044 19.8 2.1 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KFM71411.1 - 0.00042 20.1 6.3 0.0056 16.5 6.4 2.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFM71411.1 - 0.0017 18.5 5.2 0.006 16.7 5.2 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFM71411.1 - 0.0057 16.4 4.7 0.012 15.4 4.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KFM71411.1 - 0.018 15.2 2.8 0.089 13.0 2.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3450 PF11932.8 KFM71411.1 - 0.019 14.2 15.9 0.031 13.6 7.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) RINGv PF12906.7 KFM71411.1 - 0.023 14.8 2.9 0.023 14.8 2.9 2.0 2 0 0 2 2 1 0 RING-variant domain APG6_N PF17675.1 KFM71411.1 - 0.029 14.9 28.3 0.057 13.9 12.3 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-B_N PF04218.13 KFM71411.1 - 0.03 14.0 0.2 0.49 10.1 0.0 2.8 2 1 1 3 3 3 0 CENP-B N-terminal DNA-binding domain GAS PF13851.6 KFM71411.1 - 0.042 13.2 25.0 0.5 9.7 17.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prok-RING_1 PF14446.6 KFM71411.1 - 0.063 13.2 4.5 0.076 13.0 2.1 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 KFM71411.1 - 0.1 12.8 1.7 0.39 10.9 1.7 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger Baculo_PEP_C PF04513.12 KFM71411.1 - 0.1 12.7 11.9 0.14 12.2 4.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HrpB7 PF09486.10 KFM71411.1 - 0.11 12.9 4.2 0.37 11.2 0.9 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 KFM71411.1 - 0.11 11.3 24.1 0.83 8.5 10.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFM71411.1 - 0.22 11.5 26.1 0.055 13.5 9.0 3.1 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-Nse PF11789.8 KFM71411.1 - 0.28 11.0 2.1 0.78 9.6 2.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1640 PF07798.11 KFM71411.1 - 0.69 9.9 15.9 0.44 10.6 0.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1640) zf-RING-like PF08746.11 KFM71411.1 - 0.76 10.1 3.3 1.8 9.0 3.3 1.7 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KFM71411.1 - 0.94 9.4 5.3 0.79 9.7 2.9 2.2 2 0 0 2 2 1 0 PHD-finger UPF0242 PF06785.11 KFM71411.1 - 1 9.5 23.1 5.6 7.0 9.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 KFM71411.1 - 1.2 9.6 21.4 3 8.2 21.4 1.7 1 1 0 1 1 1 0 Fez1 ATG16 PF08614.11 KFM71411.1 - 1.4 9.1 24.7 2.9 8.1 15.5 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 KFM71411.1 - 1.6 9.6 25.4 0.29 12.0 14.1 2.7 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain HMMR_N PF15905.5 KFM71411.1 - 2.1 7.8 29.3 4.4 6.7 18.4 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HemX PF04375.14 KFM71411.1 - 2.2 7.5 16.5 0.3 10.3 6.3 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3677 PF12432.8 KFM71411.1 - 3.8 7.9 8.8 8.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) Tropomyosin_1 PF12718.7 KFM71411.1 - 7.2 6.8 28.1 0.53 10.4 14.2 3.5 2 1 1 3 3 3 0 Tropomyosin like Fungal_TACC PF12709.7 KFM71411.1 - 7.6 7.1 25.0 15 6.1 4.4 4.5 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins TMF_DNA_bd PF12329.8 KFM71411.1 - 8.3 6.5 33.2 0.068 13.2 20.5 3.0 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mlf1IP PF10248.9 KFM71412.1 - 7.1e-07 29.3 1.4 7.1e-07 29.3 1.4 2.1 2 0 0 2 2 2 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein DUF892 PF05974.12 KFM71412.1 - 0.098 12.7 0.1 14 5.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF892) HTH_Tnp_Tc3_2 PF01498.18 KFM71413.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71413.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease G-patch PF01585.23 KFM71414.1 - 0.00041 20.2 0.0 0.00073 19.4 0.0 1.4 1 0 0 1 1 1 1 G-patch domain PDDEXK_2 PF12784.7 KFM71417.1 - 0.0073 15.9 0.1 0.0073 15.9 0.1 1.0 1 0 0 1 1 1 1 PD-(D/E)XK nuclease family transposase GTP_EFTU_D2 PF03144.25 KFM71418.1 - 2.4e-15 56.6 0.5 3.5e-15 56.1 0.5 1.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KFM71418.1 - 3.8e-14 52.9 0.1 1.3e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D4 PF14578.6 KFM71418.1 - 0.0041 17.0 0.2 0.0063 16.4 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu domain 4 5HT_transport_N PF03491.13 KFM71418.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus ASC PF00858.24 KFM71419.1 - 0.013 14.5 0.0 0.014 14.4 0.0 1.0 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel MULE PF10551.9 KFM71421.1 - 1.2e-12 48.0 0.2 1.8e-12 47.5 0.2 1.3 1 0 0 1 1 1 1 MULE transposase domain LpxB PF02684.15 KFM71421.1 - 0.11 11.3 0.2 0.15 10.9 0.2 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase SWIM PF04434.17 KFM71422.1 - 0.0056 16.3 2.4 0.013 15.2 2.4 1.6 1 0 0 1 1 1 1 SWIM zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM71423.1 - 2.5e-16 59.6 2.2 8.1e-16 58.0 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71423.1 - 1.9e-13 50.4 0.0 3.6e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71423.1 - 4.2e-07 29.6 1.6 9.5e-07 28.5 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71423.1 - 0.0038 17.0 0.5 0.01 15.6 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71423.1 - 5.5 7.7 15.9 0.17 12.5 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71424.1 - 5.2e-09 36.2 1.4 1.1e-08 35.2 1.4 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71424.1 - 0.00031 20.5 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_12 PF08461.10 KFM71424.1 - 0.04 13.9 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain TRAM_LAG1_CLN8 PF03798.16 KFM71426.1 - 0.52 10.0 5.8 0.65 9.7 5.8 1.1 1 0 0 1 1 1 0 TLC domain TRAM_LAG1_CLN8 PF03798.16 KFM71427.1 - 4.5e-15 55.9 8.2 4.5e-15 55.9 8.2 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFM71427.1 - 2.7e-06 26.9 0.1 5.8e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 TRAM1-like protein zf-H2C2_2 PF13465.6 KFM71430.1 - 1.1e-102 332.3 96.0 2.4e-08 34.1 0.3 15.1 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71430.1 - 4.9e-68 222.0 118.4 2.5e-05 24.5 0.5 14.8 15 0 0 15 15 15 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71430.1 - 1.5e-46 153.0 109.3 0.0012 19.5 0.4 14.7 15 0 0 15 15 14 13 C2H2-type zinc finger zf-met PF12874.7 KFM71430.1 - 1e-33 114.7 118.9 0.0017 18.7 1.9 15.3 16 0 0 16 16 15 12 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM71430.1 - 9.1e-18 63.8 108.4 0.0093 15.9 0.2 15.4 16 0 0 16 16 15 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM71430.1 - 1.9e-15 56.7 86.8 0.044 14.1 1.6 14.2 14 1 1 15 15 15 9 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM71430.1 - 3.3e-15 55.5 73.9 0.069 12.9 0.4 13.5 13 0 0 13 13 13 8 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM71430.1 - 1.4e-10 41.0 39.8 0.046 13.7 0.0 9.0 2 2 8 11 11 11 7 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM71430.1 - 6.4e-09 35.9 14.5 0.012 15.8 0.1 6.6 1 1 5 7 7 7 3 HNH/Endo VII superfamily nuclease toxin with a HHH motif BolA PF01722.18 KFM71430.1 - 1.8e-06 28.1 22.5 1.1 9.6 0.1 6.9 1 1 8 9 9 9 2 BolA-like protein DUF2256 PF10013.9 KFM71430.1 - 0.00036 20.6 50.2 12 6.1 0.1 13.9 15 0 0 15 15 15 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3396 PF11876.8 KFM71430.1 - 0.0009 18.8 0.0 18 4.7 0.0 5.6 2 2 6 8 8 8 0 Protein of unknown function (DUF3396) zinc_ribbon_15 PF17032.5 KFM71430.1 - 0.0018 19.0 51.8 4.8 8.0 3.9 7.3 3 2 2 7 7 7 3 zinc-ribbon family zf-MYST PF17772.1 KFM71430.1 - 0.004 16.7 57.0 0.52 10.0 0.3 12.4 7 2 6 13 13 13 1 MYST family zinc finger domain TRAF6_Z2 PF18048.1 KFM71430.1 - 0.012 15.7 65.6 0.19 11.8 0.4 12.4 13 0 0 13 13 13 0 TNF receptor-associated factor 6 zinc finger 2 FYVE PF01363.21 KFM71430.1 - 0.014 15.6 71.0 0.58 10.3 5.3 7.3 1 1 5 7 7 6 0 FYVE zinc finger zf-C2HC_2 PF13913.6 KFM71430.1 - 0.014 15.3 60.7 9.1 6.3 0.5 13.7 14 0 0 14 14 14 0 zinc-finger of a C2HC-type GATase_2 PF00310.21 KFM71430.1 - 0.032 13.0 0.2 1.6 7.3 0.0 2.7 1 1 2 3 3 3 0 Glutamine amidotransferases class-II zf-C2H2_9 PF16293.5 KFM71430.1 - 0.057 13.3 61.0 4.8 7.1 0.1 13.0 5 4 9 14 14 14 0 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM71430.1 - 0.21 11.7 53.3 0.1 12.7 4.2 6.2 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type HNH_5 PF14279.6 KFM71430.1 - 0.29 11.0 69.7 0.56 10.1 2.0 11.9 6 4 6 12 12 12 0 HNH endonuclease zf-CHCC PF10276.9 KFM71430.1 - 0.52 10.4 21.8 83 3.4 0.0 9.9 12 0 0 12 12 11 0 Zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM71430.1 - 1.2 9.3 58.0 6 7.0 4.1 12.2 8 3 6 14 14 14 0 Sec23/Sec24 zinc finger C1_1 PF00130.22 KFM71430.1 - 1.6 8.7 75.0 10 6.1 0.7 12.6 1 1 12 13 13 13 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM71430.1 - 6.2 6.7 24.3 3.6 7.5 0.0 7.8 3 2 7 10 10 10 0 GAGA factor zf-Dof PF02701.15 KFM71430.1 - 6.2 7.0 40.5 2.8 8.2 0.3 9.8 1 1 10 11 11 11 0 Dof domain, zinc finger zf-DBF PF07535.12 KFM71430.1 - 6.4 7.0 60.4 6.2 7.0 0.5 11.7 13 0 0 13 13 13 0 DBF zinc finger Neur_chan_memb PF02932.16 KFM71431.1 - 6.3e-07 29.7 2.0 0.0034 17.5 0.2 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Roughex PF06020.11 KFM71431.1 - 0.052 12.6 0.1 0.059 12.5 0.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Neur_chan_LBD PF02931.23 KFM71432.1 - 1.2e-37 129.5 0.3 1.5e-37 129.2 0.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM71432.1 - 0.0016 18.5 1.3 0.0024 18.0 1.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region LRR_6 PF13516.6 KFM71433.1 - 5e-30 101.0 34.3 0.0028 17.6 0.1 11.2 11 0 0 11 11 11 9 Leucine Rich repeat LRR_4 PF12799.7 KFM71433.1 - 7.7e-17 61.1 24.1 0.00016 22.0 1.8 7.3 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KFM71433.1 - 6.5e-10 38.7 0.4 2.7e-09 36.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 KFM71433.1 - 1.1e-07 31.4 26.3 2.8 8.8 0.1 10.2 10 1 0 10 10 10 3 Leucine Rich Repeat F-box PF00646.33 KFM71433.1 - 3.3e-06 26.8 0.3 0.00048 19.9 0.0 3.6 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.6 KFM71433.1 - 0.00078 19.2 25.9 0.25 11.1 0.8 6.6 5 2 0 5 5 5 3 Leucine rich repeat HTH_5 PF01022.20 KFM71433.1 - 0.012 15.4 2.0 0.47 10.4 0.2 2.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family SAM_Ste50p PF09235.10 KFM71433.1 - 0.056 13.7 4.2 1.1 9.6 0.1 3.8 2 2 3 5 5 5 0 Ste50p, sterile alpha motif NAP PF00956.18 KFM71435.1 - 2.9e-26 92.3 8.0 1.4e-20 73.7 0.9 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Cytochrom_B562 PF07361.11 KFM71435.1 - 0.0018 18.9 1.6 0.003 18.2 1.6 1.4 1 0 0 1 1 1 1 Cytochrome b562 KaiA PF07688.12 KFM71435.1 - 0.004 17.3 0.4 0.0056 16.8 0.4 1.2 1 0 0 1 1 1 1 KaiA C-terminal domain Phage_Mu_Gam PF07352.12 KFM71435.1 - 0.0057 16.6 4.3 0.0083 16.1 3.7 1.6 1 1 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF98 PF01947.16 KFM71435.1 - 0.029 14.3 0.0 0.039 13.9 0.0 1.1 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase BBP1_C PF15272.6 KFM71435.1 - 0.062 13.1 3.4 0.087 12.6 3.4 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF4407 PF14362.6 KFM71435.1 - 0.071 12.4 0.4 0.089 12.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec34 PF04136.15 KFM71435.1 - 0.17 11.8 2.9 0.43 10.5 2.9 1.6 1 1 0 1 1 1 0 Sec34-like family SAS4 PF15460.6 KFM71435.1 - 0.17 12.0 4.0 0.14 12.3 2.2 1.6 1 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 ZapB PF06005.12 KFM71435.1 - 0.42 11.1 4.3 0.11 13.0 1.3 1.6 2 0 0 2 2 2 0 Cell division protein ZapB Nore1-SARAH PF16517.5 KFM71435.1 - 0.59 10.1 0.2 0.59 10.1 0.2 3.4 2 1 1 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain wnt PF00110.19 KFM71436.1 - 5.1e-120 400.7 21.1 5.9e-120 400.5 21.1 1.0 1 0 0 1 1 1 1 wnt family SDF PF00375.18 KFM71437.1 - 3.1e-67 227.3 13.6 3.5e-67 227.1 13.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SAM_1 PF00536.30 KFM71438.1 - 1.6e-22 79.7 0.2 5.3e-10 39.6 0.0 2.9 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM71438.1 - 1.1e-16 60.7 0.2 1e-07 32.0 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KFM71438.1 - 1.3e-07 31.2 0.0 2.7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM71438.1 - 0.00065 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain zf-H2C2_2 PF13465.6 KFM71439.1 - 6.3e-93 301.4 91.9 1.5e-08 34.7 0.5 14.1 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71439.1 - 5.9e-62 202.8 126.3 9.6e-07 28.9 1.3 14.6 15 0 0 15 15 14 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71439.1 - 2.8e-41 136.6 116.9 0.00041 20.9 1.2 14.4 14 1 1 15 15 15 11 C2H2-type zinc finger zf-met PF12874.7 KFM71439.1 - 6.7e-28 96.2 111.7 0.0045 17.3 0.9 13.1 14 0 0 14 14 13 12 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM71439.1 - 6.5e-20 70.6 73.2 0.019 14.7 0.4 12.6 12 0 0 12 12 12 10 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM71439.1 - 5e-18 64.6 85.1 0.0012 18.8 0.8 13.0 12 0 0 12 12 12 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM71439.1 - 6e-15 55.1 80.2 0.059 13.7 1.1 12.9 13 0 0 13 13 13 9 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM71439.1 - 3.7e-09 36.3 29.6 0.061 13.1 0.1 9.6 2 2 9 11 11 11 3 GAGA factor BolA PF01722.18 KFM71439.1 - 4.8e-09 36.4 22.2 0.5 10.7 0.9 7.8 1 1 8 9 9 9 4 BolA-like protein zf-C2HC_2 PF13913.6 KFM71439.1 - 1.8e-07 30.8 51.7 0.42 10.6 0.2 12.4 12 1 0 12 12 12 4 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM71439.1 - 3.2e-07 30.3 63.5 5.8 7.1 0.5 13.4 13 0 0 13 13 13 1 DBF zinc finger TRAF6_Z2 PF18048.1 KFM71439.1 - 3.5e-07 30.2 81.1 0.042 13.9 1.1 12.4 14 0 0 14 14 13 6 TNF receptor-associated factor 6 zinc finger 2 zf-Sec23_Sec24 PF04810.15 KFM71439.1 - 6.3e-07 29.3 47.8 0.44 10.6 0.0 11.9 6 4 7 13 13 12 2 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM71439.1 - 9.5e-07 28.6 61.6 1.4 8.8 0.5 12.0 2 1 10 12 12 12 5 C2H2 type zinc-finger (1 copy) Tox-HNH-HHH PF15637.6 KFM71439.1 - 2.6e-05 24.3 12.6 3.1 8.0 0.1 5.9 1 1 7 8 8 8 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-RRPl_C4 PF17026.5 KFM71439.1 - 0.00038 20.5 56.4 0.016 15.3 5.5 6.0 1 1 4 5 5 5 2 Putative ribonucleoprotein zinc-finger pf C4 type DUF3396 PF11876.8 KFM71439.1 - 0.00099 18.6 0.0 26 4.2 0.0 4.9 1 1 4 6 6 6 0 Protein of unknown function (DUF3396) IGPD PF00475.18 KFM71439.1 - 0.027 14.8 14.2 3.6 7.9 0.0 5.5 1 1 4 6 6 6 0 Imidazoleglycerol-phosphate dehydratase zinc_ribbon_15 PF17032.5 KFM71439.1 - 0.03 15.1 58.0 0.66 10.8 2.4 6.9 3 3 3 7 7 7 0 zinc-ribbon family zf-MYST PF17772.1 KFM71439.1 - 0.039 13.5 49.3 3.8 7.2 0.1 11.2 9 1 2 11 11 11 0 MYST family zinc finger domain FYVE PF01363.21 KFM71439.1 - 0.04 14.1 68.1 0.6 10.3 10.2 6.5 1 1 4 6 6 6 0 FYVE zinc finger C1_1 PF00130.22 KFM71439.1 - 0.18 11.7 79.6 1.5 8.7 7.0 11.0 1 1 11 12 12 12 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD_kinase PF01513.21 KFM71439.1 - 0.28 10.3 0.7 37 3.4 0.2 3.4 1 1 1 2 2 2 0 ATP-NAD kinase DUF2256 PF10013.9 KFM71439.1 - 0.42 10.8 50.2 9.4 6.5 0.1 12.4 14 0 0 14 14 12 0 Uncharacterized protein conserved in bacteria (DUF2256) PqqA PF08042.11 KFM71439.1 - 1.6 8.8 8.2 5.2e+02 0.9 0.0 6.9 9 0 0 9 9 9 0 PqqA family zf-C2H2_2 PF12756.7 KFM71439.1 - 4.9 7.5 92.4 2 8.8 2.5 11.4 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) Ribosomal_L35p PF01632.19 KFM71439.1 - 5.4 7.6 24.2 6.8 7.3 0.5 7.3 4 4 3 7 7 7 0 Ribosomal protein L35 zf-H2C2_2 PF13465.6 KFM71440.1 - 3e-78 255.0 111.2 1.1e-08 35.1 1.9 14.1 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71440.1 - 1.4e-58 192.2 137.0 2.2e-06 27.8 3.4 14.1 14 0 0 14 14 14 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71440.1 - 5.9e-37 123.1 127.9 0.00053 20.6 2.7 13.9 14 0 0 14 14 14 12 C2H2-type zinc finger zf-met PF12874.7 KFM71440.1 - 7.3e-33 112.0 106.7 0.00034 20.9 2.3 13.1 11 1 1 12 12 12 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM71440.1 - 1.8e-18 66.3 72.6 0.011 16.0 0.4 13.5 12 1 1 13 13 13 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM71440.1 - 1e-10 41.4 89.8 0.0049 16.8 0.6 13.6 13 0 0 13 13 13 6 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM71440.1 - 5.9e-10 39.0 40.7 2.8 8.1 0.2 12.2 9 3 4 13 13 13 4 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM71440.1 - 4.7e-09 36.1 36.6 0.058 13.4 0.8 8.4 4 4 5 9 9 9 6 Adenylate kinase, active site lid zf-CHCC PF10276.9 KFM71440.1 - 9.5e-07 28.8 12.1 28 4.9 0.0 10.2 12 0 0 12 12 12 0 Zinc-finger domain zf-RRPl_C4 PF17026.5 KFM71440.1 - 0.00014 21.9 51.2 0.81 9.8 8.6 5.5 1 1 3 5 5 5 5 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM71440.1 - 0.00069 19.7 48.2 8 6.7 0.2 11.4 10 1 1 11 11 11 0 DBF zinc finger Tox-HNH-HHH PF15637.6 KFM71440.1 - 0.0024 18.0 4.8 6 7.1 0.0 4.7 1 1 5 6 6 6 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif BolA PF01722.18 KFM71440.1 - 0.0035 17.6 32.4 6.9 7.0 1.9 7.5 1 1 6 7 7 7 2 BolA-like protein PqqA PF08042.11 KFM71440.1 - 0.023 14.7 0.7 1e+02 3.2 0.0 5.7 7 0 0 7 7 7 0 PqqA family C1_1 PF00130.22 KFM71440.1 - 0.049 13.5 76.8 1 9.3 3.1 11.2 2 1 8 11 11 11 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.6 KFM71440.1 - 0.062 13.1 100.5 0.087 12.6 0.9 14.1 14 0 0 14 14 14 0 C2H2-type zinc-finger domain TRAF6_Z2 PF18048.1 KFM71440.1 - 0.073 13.2 83.5 0.13 12.3 0.8 13.0 14 0 0 14 14 13 0 TNF receptor-associated factor 6 zinc finger 2 DUF2256 PF10013.9 KFM71440.1 - 0.11 12.6 47.7 6.1 7.1 0.1 11.7 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 KFM71440.1 - 0.11 12.6 65.3 0.45 10.7 11.1 6.5 1 1 5 6 6 5 0 FYVE zinc finger Mga PF05043.13 KFM71440.1 - 0.18 12.4 14.3 7 7.3 0.1 5.5 1 1 3 5 5 5 0 Mga helix-turn-helix domain Complex1_49kDa PF00346.19 KFM71440.1 - 0.25 10.4 2.3 2.9 6.9 0.3 2.9 1 1 2 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit GAGA PF09237.11 KFM71440.1 - 3.8 7.4 36.3 0.51 10.2 0.5 8.4 2 2 9 11 11 11 0 GAGA factor YyzF PF14116.6 KFM71440.1 - 5.1 7.2 42.7 35 4.5 0.1 11.2 12 0 0 12 12 12 0 YyzF-like protein Methyltransf_31 PF13847.6 KFM71441.1 - 3.1e-10 40.0 0.2 4.5e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM71441.1 - 4.2e-10 40.2 0.1 7.4e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM71441.1 - 1.6e-07 31.0 0.4 3.5e-07 29.9 0.4 1.6 1 1 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 KFM71441.1 - 2e-07 30.4 1.6 1.4e-06 27.5 1.6 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KFM71441.1 - 9.7e-07 28.5 0.3 1.6e-06 27.8 0.3 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 KFM71441.1 - 3e-06 26.7 0.4 5.8e-06 25.8 0.1 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KFM71441.1 - 5.2e-06 26.1 0.6 7.5e-06 25.5 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KFM71441.1 - 5.5e-06 26.5 0.1 7.8e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM71441.1 - 1.1e-05 25.9 0.1 2.1e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM71441.1 - 2.2e-05 24.4 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM71441.1 - 0.00018 21.2 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 KFM71441.1 - 0.00022 20.8 0.1 0.0004 19.9 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 KFM71441.1 - 0.0011 19.6 0.1 0.0024 18.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFM71441.1 - 0.0033 17.2 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KFM71441.1 - 0.0091 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Met_10 PF02475.16 KFM71441.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.18 KFM71441.1 - 0.012 15.3 1.0 0.53 9.9 0.5 2.7 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KFM71441.1 - 0.022 14.7 1.5 0.024 14.6 0.3 1.8 2 1 0 2 2 2 0 Methyltransferase domain MethyltransfD12 PF02086.15 KFM71441.1 - 0.031 14.0 0.5 0.069 12.8 0.1 1.8 2 1 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_20 PF12147.8 KFM71441.1 - 0.045 12.9 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase AviRa PF11599.8 KFM71441.1 - 0.051 13.0 0.3 0.22 11.0 0.1 2.0 2 0 0 2 2 2 0 RRNA methyltransferase AviRa Pox_MCEL PF03291.16 KFM71441.1 - 0.062 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme FtsJ PF01728.19 KFM71441.1 - 0.069 13.2 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.14 KFM71441.1 - 0.071 12.5 0.5 0.12 11.8 0.5 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB NodS PF05401.11 KFM71441.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) RhoGEF PF00621.20 KFM71442.1 - 4.1e-43 147.7 3.4 4.1e-43 147.7 3.4 1.6 2 0 0 2 2 2 1 RhoGEF domain FCH PF00611.23 KFM71442.1 - 0.00011 22.4 0.4 0.11 12.8 0.1 2.9 2 0 0 2 2 2 2 Fes/CIP4, and EFC/F-BAR homology domain PH PF00169.29 KFM71442.1 - 0.013 16.0 0.3 0.69 10.5 0.1 2.6 2 0 0 2 2 2 0 PH domain RBD PF02196.15 KFM71443.1 - 3e-05 24.0 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Raf-like Ras-binding domain PDZ PF00595.24 KFM71443.1 - 6.1e-05 23.3 0.0 9.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM71443.1 - 0.0014 18.9 0.0 0.0024 18.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM71443.1 - 0.0042 16.9 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tiam_CC_Ex PF18385.1 KFM71444.1 - 1.3e-19 70.4 0.0 1.8e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain PH PF00169.29 KFM71444.1 - 3.7e-06 27.4 0.0 1.8e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KFM71444.1 - 1.3e-05 25.5 0.0 8.5e-05 22.9 0.0 1.9 1 1 1 2 2 2 1 Pleckstrin homology domain MYO10_CC PF16735.5 KFM71444.1 - 0.00014 21.8 2.4 0.00035 20.6 2.4 1.6 1 1 0 1 1 1 1 Unconventional myosin-X coiled coil domain eIF-4B PF06273.11 KFM71444.1 - 0.018 14.1 0.2 0.024 13.7 0.2 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Jnk-SapK_ap_N PF09744.9 KFM71444.1 - 0.039 14.2 0.9 0.052 13.8 0.9 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HTH_Tnp_Tc3_2 PF01498.18 KFM71445.1 - 2.3e-16 59.8 2.2 5.2e-16 58.6 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71445.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71445.1 - 9.5e-08 31.7 0.7 4.4e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71445.1 - 0.00086 19.0 0.3 0.0025 17.6 0.3 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71445.1 - 0.0028 17.7 0.2 0.0086 16.2 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM71445.1 - 0.92 10.2 14.5 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Macoilin PF09726.9 KFM71446.1 - 6.7 5.1 20.4 61 2.0 20.4 2.0 1 1 0 1 1 1 0 Macoilin family HTH_Tnp_Tc3_2 PF01498.18 KFM71448.1 - 2.3e-16 59.8 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71448.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3987 PF13148.6 KFM71449.1 - 2.3 7.1 5.8 2.6 7.0 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) WH2 PF02205.20 KFM71450.1 - 1.2e-05 24.9 0.4 2.5e-05 23.9 0.4 1.6 1 0 0 1 1 1 1 WH2 motif zf-C3HC4_3 PF13920.6 KFM71451.1 - 1.6e-14 53.5 12.3 3.5e-14 52.4 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM71451.1 - 6.6e-10 38.7 12.4 1.5e-09 37.5 12.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rad10 PF03834.14 KFM71451.1 - 0.0016 18.4 0.2 0.0031 17.5 0.2 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) zf-RING_2 PF13639.6 KFM71451.1 - 0.0048 17.2 14.3 0.0048 17.2 14.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFM71451.1 - 7.7 6.6 19.8 0.067 13.2 11.4 2.0 2 0 0 2 2 2 0 zinc-RING finger domain LRR_4 PF12799.7 KFM71452.1 - 1.2e-06 28.8 14.3 0.012 16.0 1.1 6.1 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM71452.1 - 0.0023 17.8 7.4 0.056 13.5 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich repeat GRAM PF02893.20 KFM71452.1 - 0.0058 16.5 0.5 0.022 14.6 0.1 2.1 2 0 0 2 2 2 1 GRAM domain TetR_C_8 PF14278.6 KFM71452.1 - 0.31 11.2 3.4 0.35 11.0 1.8 1.9 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region zf-C2H2_jaz PF12171.8 KFM71453.1 - 9.4e-10 38.5 5.3 1.4e-09 38.0 5.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM71453.1 - 0.0037 17.6 1.2 0.0063 16.8 1.1 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM71453.1 - 0.045 14.6 1.7 0.091 13.6 1.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM71453.1 - 0.3 11.6 3.9 0.62 10.6 3.9 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type PDZ PF00595.24 KFM71454.1 - 1.8e-43 146.8 7.0 1.5e-21 76.6 1.1 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM71454.1 - 5.4e-13 48.6 2.3 1.1e-05 25.2 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFM71454.1 - 6e-11 42.5 3.6 2.9e-05 24.3 0.1 2.2 2 0 0 2 2 2 2 PDZ domain Ras PF00071.22 KFM71456.1 - 2.5e-14 53.2 0.1 2.8e-14 53.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM71456.1 - 1.5e-12 47.8 0.1 1.9e-12 47.4 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM71456.1 - 0.036 13.5 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family MG2 PF01835.19 KFM71459.1 - 2.6e-07 31.0 0.0 2.8e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 MG2 domain MG3 PF17791.1 KFM71459.1 - 1.5e-05 25.2 0.0 4.4e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG4 PF17789.1 KFM71460.1 - 0.0016 18.5 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 Macroglobulin domain MG4 Coatomer_E PF04733.14 KFM71460.1 - 0.034 13.6 0.6 0.12 11.8 0.0 1.8 1 1 1 2 2 2 0 Coatomer epsilon subunit A2M_BRD PF07703.14 KFM71461.1 - 1.2e-11 45.1 0.1 3e-11 43.8 0.1 1.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFM71461.1 - 4.5e-09 36.0 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Alpha-2-macroglobulin family Ldl_recept_a PF00057.18 KFM71461.1 - 3.4e-05 24.0 11.2 5.5e-05 23.3 11.2 1.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TED_complement PF07678.14 KFM71462.1 - 0.0038 16.3 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 KFM71462.1 - 0.0053 17.4 0.0 0.0093 16.6 0.0 1.5 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM71463.1 - 4.3e-16 58.9 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71463.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71463.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71463.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71463.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM71464.1 - 1.6e-10 40.9 0.0 1.8e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM71467.1 - 3.1e-93 302.4 102.5 2.1e-08 34.2 2.8 15.0 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71467.1 - 5.7e-63 206.0 135.1 1.9e-06 28.0 2.7 14.1 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71467.1 - 3.1e-44 145.8 127.5 0.00029 21.4 1.6 14.1 14 0 0 14 14 14 13 C2H2-type zinc finger zf-met PF12874.7 KFM71467.1 - 4e-25 87.4 122.2 0.0038 17.6 2.5 14.2 13 1 0 14 14 14 11 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM71467.1 - 3.2e-18 65.1 74.7 0.0034 17.1 0.2 14.3 14 0 0 14 14 14 9 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM71467.1 - 1.8e-16 59.7 110.9 0.00077 19.4 1.0 14.8 14 1 0 14 14 14 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM71467.1 - 2.7e-08 33.9 92.2 0.0065 16.7 0.9 13.5 13 1 1 14 14 14 7 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM71467.1 - 8.3e-06 25.8 53.8 0.22 11.6 0.2 13.1 6 3 8 14 14 14 2 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM71467.1 - 4.4e-05 23.2 30.0 1.1 9.1 0.0 9.3 2 2 9 11 11 11 3 GAGA factor TRAF6_Z2 PF18048.1 KFM71467.1 - 5.1e-05 23.3 74.7 0.17 12.0 0.2 13.5 14 0 0 14 14 14 4 TNF receptor-associated factor 6 zinc finger 2 zf-RRPl_C4 PF17026.5 KFM71467.1 - 0.00044 20.3 64.1 0.3 11.2 3.6 6.7 1 1 6 7 7 7 4 Putative ribonucleoprotein zinc-finger pf C4 type FYVE PF01363.21 KFM71467.1 - 0.0045 17.1 77.3 0.083 13.0 4.4 6.9 1 1 4 6 6 6 2 FYVE zinc finger zf-C2H2_2 PF12756.7 KFM71467.1 - 0.0069 16.7 102.6 0.43 10.9 2.9 12.2 1 1 9 10 10 10 3 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM71467.1 - 0.0074 16.1 70.5 1.7 8.5 1.4 13.3 2 1 12 14 14 14 1 C2H2 type zinc-finger (1 copy) TAFII28 PF04719.14 KFM71467.1 - 0.013 15.6 0.2 20 5.4 0.0 4.1 2 1 1 4 4 4 0 hTAFII28-like protein conserved region Tox-HNH-HHH PF15637.6 KFM71467.1 - 0.014 15.5 13.5 1.4 9.1 0.5 5.4 2 2 6 8 8 8 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif ADK_lid PF05191.14 KFM71467.1 - 0.016 15.2 56.0 1.7 8.7 0.9 9.1 5 2 1 7 7 7 0 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 KFM71467.1 - 0.093 12.5 0.6 0.093 12.5 0.6 12.5 13 0 0 13 13 12 0 zinc-finger C2H2-type BolA PF01722.18 KFM71467.1 - 0.25 11.6 31.8 0.75 10.1 0.8 7.6 1 1 7 8 8 8 0 BolA-like protein zf-DBF PF07535.12 KFM71467.1 - 0.39 10.9 0.0 0.39 10.9 0.0 11.3 12 1 1 13 13 13 0 DBF zinc finger zinc_ribbon_15 PF17032.5 KFM71467.1 - 2.5 8.9 62.9 7 7.5 1.7 7.4 1 1 8 9 9 9 0 zinc-ribbon family PqqA PF08042.11 KFM71467.1 - 7.1 6.8 5.3 3.2e+02 1.6 0.0 4.7 5 0 0 5 5 5 0 PqqA family zf-H2C2_2 PF13465.6 KFM71468.1 - 2.2e-42 141.7 47.0 7e-08 32.6 1.0 7.7 7 0 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71468.1 - 2.4e-17 62.4 59.1 3.3e-05 24.1 1.0 7.7 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-met PF12874.7 KFM71468.1 - 4.7e-16 58.6 44.4 0.00056 20.2 0.9 6.5 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM71468.1 - 3.3e-12 46.2 55.0 0.00054 20.6 0.8 7.7 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM71468.1 - 4.4e-12 46.0 25.6 0.0051 17.1 0.2 5.9 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM71468.1 - 2.6e-06 27.3 39.2 0.077 13.0 0.4 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger BolA PF01722.18 KFM71468.1 - 4.4e-05 23.7 4.2 0.18 12.1 0.1 3.1 2 1 2 4 4 3 2 BolA-like protein GAGA PF09237.11 KFM71468.1 - 0.015 15.1 9.8 2.8 7.8 0.3 4.5 1 1 4 5 5 5 0 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM71468.1 - 0.026 14.5 15.7 17 5.6 0.9 6.8 5 2 2 7 7 7 0 Sec23/Sec24 zinc finger Zf_RING PF16744.5 KFM71468.1 - 0.077 13.1 30.8 2.5 8.3 7.1 5.9 1 1 4 5 5 5 0 KIAA1045 RING finger zf-DBF PF07535.12 KFM71468.1 - 0.37 10.9 17.9 8.7 6.5 0.1 5.5 5 0 0 5 5 5 0 DBF zinc finger zf-CHCC PF10276.9 KFM71468.1 - 0.41 10.7 7.7 14 5.9 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KFM71468.1 - 1.9 8.5 20.8 18 5.3 0.2 5.5 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFM71469.1 - 2.7e-86 280.4 103.9 2.1e-08 34.2 0.3 16.2 16 0 0 16 16 16 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71469.1 - 7.1e-47 155.3 124.7 2.4e-05 24.5 4.4 14.7 15 0 0 15 15 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71469.1 - 1.3e-37 125.2 117.7 0.0011 19.6 2.0 14.8 15 0 0 15 15 15 13 C2H2-type zinc finger zf-met PF12874.7 KFM71469.1 - 2.4e-16 59.5 105.7 0.0062 16.9 0.6 14.0 14 0 0 14 14 13 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM71469.1 - 2e-12 46.8 96.9 0.0045 17.0 2.2 13.8 15 0 0 15 15 13 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM71469.1 - 1.6e-11 43.8 84.6 0.018 14.8 0.5 14.7 15 0 0 15 15 15 6 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM71469.1 - 1e-06 28.8 75.6 0.052 13.9 0.4 13.1 13 0 0 13 13 13 6 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM71469.1 - 1.8e-05 24.6 43.4 0.74 9.9 0.1 8.5 6 2 1 7 7 7 4 Adenylate kinase, active site lid zf-C2H2_9 PF16293.5 KFM71469.1 - 7.1e-05 22.6 56.3 2.7 7.9 0.3 12.8 6 3 7 13 13 13 3 C2H2 type zinc-finger (1 copy) RsfS PF02410.15 KFM71469.1 - 0.0018 18.7 2.9 1.4 9.4 0.0 4.5 1 1 1 3 3 3 1 Ribosomal silencing factor during starvation GAGA PF09237.11 KFM71469.1 - 0.013 15.2 34.7 4.5 7.2 0.1 9.2 4 3 7 11 11 11 0 GAGA factor Tox-HNH-HHH PF15637.6 KFM71469.1 - 0.024 14.8 7.4 34 4.7 0.0 5.4 2 1 3 7 7 7 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif TRAF6_Z2 PF18048.1 KFM71469.1 - 0.047 13.8 1.7 0.047 13.8 1.7 13.5 15 0 0 15 15 15 0 TNF receptor-associated factor 6 zinc finger 2 zf-Sec23_Sec24 PF04810.15 KFM71469.1 - 0.061 13.4 48.5 0.075 13.1 0.3 11.6 11 2 2 13 13 13 0 Sec23/Sec24 zinc finger FYVE PF01363.21 KFM71469.1 - 0.51 10.5 71.8 0.52 10.5 8.2 7.5 2 2 6 8 8 8 0 FYVE zinc finger PqqA PF08042.11 KFM71469.1 - 1.3 9.1 6.2 2.7e+02 1.8 0.1 6.5 9 0 0 9 9 9 0 PqqA family zf-RRPl_C4 PF17026.5 KFM71469.1 - 2.2 8.5 57.1 2.3 8.3 1.5 6.4 2 2 4 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM71469.1 - 2.8 8.1 55.0 14 5.9 0.1 11.9 13 0 0 13 13 12 0 DBF zinc finger zf-MYST PF17772.1 KFM71469.1 - 7.5 6.2 61.3 0.47 10.1 0.5 11.5 7 5 5 12 12 12 0 MYST family zinc finger domain Viral_cys_rich PF08008.12 KFM71469.1 - 7.9 6.6 13.6 27 4.9 0.2 5.1 3 2 2 5 5 5 0 Viral cysteine rich Dimer_Tnp_hAT PF05699.14 KFM71470.1 - 9.6e-09 34.9 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HTH_Tnp_Tc3_2 PF01498.18 KFM71472.1 - 7.7e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71472.1 - 1.6e-15 57.1 0.1 1.9e-14 53.6 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71472.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71472.1 - 0.0025 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71472.1 - 0.016 15.3 0.1 0.065 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71472.1 - 0.035 14.1 0.4 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix RVT_1 PF00078.27 KFM71474.1 - 3.6e-16 59.4 0.2 8.1e-16 58.2 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.22 KFM71475.1 - 3.7e-73 246.8 0.2 4.1e-73 246.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nt_Gln_amidase PF09764.9 KFM71476.1 - 1.7e-58 197.2 0.3 2.1e-58 197.0 0.3 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase Nramp PF01566.18 KFM71477.1 - 1e-117 393.1 11.0 2e-117 392.2 11.0 1.5 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein RMI1_C PF16099.5 KFM71478.1 - 1.7e-05 24.7 0.4 1.7e-05 24.7 0.4 1.0 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold HTH_Tnp_Tc3_2 PF01498.18 KFM71479.1 - 1.8e-09 37.7 0.4 3.6e-09 36.8 0.4 1.5 1 0 0 1 1 1 1 Transposase MarR_2 PF12802.7 KFM71479.1 - 0.00059 19.7 0.0 0.038 13.9 0.0 2.5 2 1 0 2 2 2 1 MarR family HTH_20 PF12840.7 KFM71479.1 - 0.00079 19.4 0.0 0.038 14.1 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM71479.1 - 0.0018 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 KFM71479.1 - 0.0077 16.3 0.2 0.077 13.1 0.0 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase MarR PF01047.22 KFM71479.1 - 0.031 14.2 0.0 2.8 7.9 0.0 2.7 3 0 0 3 3 3 0 MarR family HTH_32 PF13565.6 KFM71479.1 - 1.1 10.0 4.5 8.9 7.0 0.4 2.3 1 1 1 2 2 2 0 Homeodomain-like domain RMI1_N PF08585.12 KFM71480.1 - 5.2e-20 72.1 1.6 8e-20 71.5 0.1 1.9 2 0 0 2 2 2 1 RecQ mediated genome instability protein RMI1_N PF08585.12 KFM71481.1 - 1.4e-22 80.5 0.1 1.7e-22 80.3 0.1 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein CNOT1_HEAT PF16418.5 KFM71481.1 - 0.094 12.8 0.3 0.26 11.4 0.2 1.7 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF5361 PF17318.2 KFM71482.1 - 0.014 15.6 1.2 2 8.7 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5361) UPRTase PF14681.6 KFM71484.1 - 1.6e-53 181.3 0.0 2e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFM71484.1 - 0.00011 21.8 0.2 0.0002 20.9 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DUF302 PF03625.14 KFM71484.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF302 DnaJ_C PF01556.18 KFM71486.1 - 5.4e-25 88.2 0.0 7.6e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFM71486.1 - 1.4e-06 28.5 16.3 3.5e-06 27.3 16.4 1.6 1 1 0 1 1 1 1 DnaJ central domain PTEN_C2 PF10409.9 KFM71486.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein zinc_ribbon_4 PF13717.6 KFM71486.1 - 0.61 10.0 8.6 9.6 6.2 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.6 KFM71486.1 - 1.8 8.6 8.6 4.4 7.4 8.8 1.9 1 1 0 1 1 1 0 CpXC protein TackOD1 PF18551.1 KFM71486.1 - 9.9 5.8 11.5 7 6.3 8.8 1.9 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DnaJ PF00226.31 KFM71487.1 - 5.8e-28 96.8 3.6 1e-27 96.0 3.6 1.4 1 0 0 1 1 1 1 DnaJ domain Dimer_Tnp_hAT PF05699.14 KFM71489.1 - 2.1e-07 30.7 0.0 5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KFM71489.1 - 5.1e-07 29.7 1.0 0.0079 16.1 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Propep_M14 PF02244.16 KFM71489.1 - 2.9 8.4 5.5 4.3 7.8 0.7 3.1 4 0 0 4 4 4 0 Carboxypeptidase activation peptide Ig_3 PF13927.6 KFM71491.1 - 1.9e-13 50.8 0.0 2.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM71491.1 - 3.4e-13 49.5 0.0 4.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM71491.1 - 3.2e-11 43.4 0.0 4.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM71491.1 - 4.1e-08 33.3 0.0 6.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM71491.1 - 0.00026 21.1 0.0 0.029 14.5 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM71491.1 - 0.0013 18.8 0.0 0.0018 18.3 0.0 1.4 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM71491.1 - 0.013 15.8 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin C1-set domain Serpin PF00079.20 KFM71492.1 - 1.6e-94 317.3 0.5 1.7e-94 317.2 0.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFM71493.1 - 3.5e-81 273.4 1.0 3.9e-81 273.2 1.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) E1-E2_ATPase PF00122.20 KFM71494.1 - 1.7e-37 128.7 2.5 2.1e-37 128.4 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 KFM71494.1 - 8.4e-25 87.3 0.1 1.8e-24 86.2 0.1 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KFM71494.1 - 2.2e-15 57.5 0.0 4.5e-05 23.8 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFM71494.1 - 2.3e-06 27.6 0.0 5.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFM71494.1 - 1.6e-05 24.5 0.0 3.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus 6PGD PF00393.19 KFM71495.1 - 3e-126 420.7 0.0 3.4e-126 420.5 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFM71495.1 - 5.2e-32 111.2 0.0 7.7e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFM71495.1 - 0.0048 17.1 0.0 0.024 14.9 0.0 2.1 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DDE_3 PF13358.6 KFM71496.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.6 KFM71497.1 - 8.6e-16 58.0 0.1 1e-14 54.5 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71497.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM71498.1 - 2.6e-19 69.2 3.9 5.4e-19 68.2 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71498.1 - 4.2e-16 59.0 0.0 2.1e-15 56.8 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71498.1 - 4.5e-07 30.4 1.9 4.5e-07 30.4 1.9 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KFM71498.1 - 5.1e-07 29.7 0.9 0.00024 21.1 0.0 2.8 3 0 0 3 3 2 2 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM71498.1 - 5.6e-06 26.4 2.4 0.00043 20.4 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM71498.1 - 3.8e-05 23.6 0.7 0.0005 20.0 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KFM71498.1 - 5.3e-05 22.9 3.8 0.00056 19.6 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM71498.1 - 0.00016 21.5 0.6 0.0026 17.6 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM71498.1 - 0.0013 18.6 0.3 0.021 14.8 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM71498.1 - 0.026 14.1 0.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TrmB PF01978.19 KFM71498.1 - 0.077 12.9 0.2 6.5 6.7 0.0 3.0 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_22 PF13309.6 KFM71498.1 - 0.12 12.5 0.0 24 5.1 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_17 PF12728.7 KFM71498.1 - 0.12 12.5 0.1 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.6 KFM71499.1 - 5.2e-16 58.7 0.1 5.9e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71499.1 - 7.9e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71499.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71499.1 - 0.0026 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71499.1 - 0.016 15.3 0.1 0.065 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71499.1 - 0.035 14.1 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM71500.1 - 2.2e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71500.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Calsequestrin PF01216.17 KFM71502.1 - 3.5e-41 141.5 0.0 4.4e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.6 KFM71502.1 - 3e-11 43.6 0.0 6.9e-11 42.4 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain Ig_3 PF13927.6 KFM71502.1 - 1.2e-05 25.8 0.2 2.9e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM71502.1 - 0.00062 19.8 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFM71502.1 - 0.0046 17.1 0.2 0.039 14.1 0.2 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain PGDYG PF14083.6 KFM71502.1 - 0.021 15.1 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 PGDYG protein T-box PF00907.22 KFM71503.1 - 1.4e-32 113.4 0.1 1.5e-32 113.3 0.1 1.0 1 0 0 1 1 1 1 T-box HTH_Tnp_Tc3_2 PF01498.18 KFM71504.1 - 1.9e-16 60.1 2.2 4.3e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71504.1 - 9.1e-14 51.4 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3539 PF12058.8 KFM71507.1 - 0.13 12.4 0.0 0.51 10.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) Sushi PF00084.20 KFM71508.1 - 7.2e-47 157.8 31.4 3.4e-08 34.0 0.9 6.2 6 0 0 6 6 6 6 Sushi repeat (SCR repeat) Trypsin PF00089.26 KFM71509.1 - 8.5e-45 153.2 0.0 1.3e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin VWA PF00092.28 KFM71509.1 - 5.3e-38 131.0 0.4 1.8e-37 129.3 0.2 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFM71509.1 - 1.8e-13 51.0 0.0 6.2e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Sushi PF00084.20 KFM71509.1 - 6.7e-07 29.8 0.2 1.6e-06 28.6 0.2 1.7 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF1986 PF09342.11 KFM71509.1 - 9.3e-07 29.2 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) VWA_CoxE PF05762.14 KFM71509.1 - 0.00052 19.5 0.0 0.00086 18.8 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Trypsin_2 PF13365.6 KFM71509.1 - 0.0016 19.4 0.0 0.0028 18.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain zf-UBP_var PF17807.1 KFM71510.1 - 0.014 15.2 0.4 0.11 12.3 0.0 2.0 1 1 1 2 2 2 0 Variant UBP zinc finger V-ATPase_G PF03179.15 KFM71511.1 - 1.9e-31 108.7 15.6 2.1e-31 108.6 15.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit CpeT PF06206.11 KFM71511.1 - 0.0062 16.5 0.7 0.007 16.3 0.7 1.1 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) DCB PF16213.5 KFM71511.1 - 0.02 14.6 6.4 0.021 14.5 6.4 1.0 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF3928 PF13065.6 KFM71511.1 - 0.029 15.1 0.6 0.047 14.4 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3928) DDHD PF02862.17 KFM71511.1 - 0.19 11.8 1.7 0.2 11.8 1.7 1.1 1 0 0 1 1 1 0 DDHD domain SNARE PF05739.19 KFM71511.1 - 0.28 11.2 4.2 0.54 10.3 0.1 2.7 2 1 2 4 4 3 0 SNARE domain DUF3573 PF12097.8 KFM71511.1 - 1.2 7.8 2.7 1.4 7.7 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF883 PF05957.13 KFM71511.1 - 3.7 8.2 9.2 1.6 9.4 4.6 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Ras PF00071.22 KFM71513.1 - 1.1e-19 70.7 0.0 1.5e-19 70.2 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFM71513.1 - 0.00056 20.1 0.1 0.0097 16.1 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Piwi PF02171.17 KFM71514.1 - 1.9e-86 290.0 0.4 1.9e-86 290.0 0.4 1.5 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.22 KFM71514.1 - 1.2e-33 115.8 0.2 2.5e-33 114.8 0.2 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KFM71514.1 - 5.4e-05 22.8 0.0 0.00016 21.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KFM71514.1 - 0.01 16.4 0.1 0.028 15.0 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of argonaute ArgoMid PF16487.5 KFM71514.1 - 0.1 12.9 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 Mid domain of argonaute Gtr1_RagA PF04670.12 KFM71515.1 - 1.2e-71 240.7 2.1 1.7e-71 240.2 2.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM71515.1 - 2.4e-05 23.8 0.0 5.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFM71515.1 - 5e-05 23.5 0.0 9.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM71515.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM71515.1 - 0.0016 18.0 0.3 0.0022 17.6 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM71515.1 - 0.0019 18.3 0.0 0.0055 16.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KFM71515.1 - 0.0063 16.1 0.2 0.011 15.3 0.2 1.5 1 0 0 1 1 1 1 Ras family AAA_14 PF13173.6 KFM71515.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM71515.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_L5 PF00281.19 KFM71516.1 - 1e-21 77.0 0.1 1e-20 73.8 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KFM71516.1 - 2e-21 76.0 0.0 3.3e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus HTH_ABP1_N PF18107.1 KFM71516.1 - 0.13 11.9 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain PKI PF02827.16 KFM71518.1 - 1.8e-15 56.9 0.4 2.2e-15 56.6 0.4 1.2 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor YTH PF04146.15 KFM71520.1 - 2.5e-42 144.6 0.0 2.5e-42 144.6 0.0 4.1 2 2 0 2 2 2 1 YT521-B-like domain Peptidase_C12 PF01088.21 KFM71521.1 - 4.1e-63 212.9 0.5 4.6e-63 212.8 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HTH_Tnp_Tc3_2 PF01498.18 KFM71522.1 - 2.4e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71522.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Homeodomain PF00046.29 KFM71523.1 - 0.0021 17.8 4.0 0.0021 17.8 4.0 1.9 2 0 0 2 2 2 1 Homeodomain Cnn_1N PF07989.11 KFM71524.1 - 0.0074 16.4 6.3 0.011 15.8 6.3 1.3 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 FAM76 PF16046.5 KFM71524.1 - 0.11 11.8 3.0 0.11 11.8 3.0 1.0 1 0 0 1 1 1 0 FAM76 protein HTH_Tnp_Tc3_2 PF01498.18 KFM71525.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71525.1 - 8.4e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease partial_CstF PF15861.5 KFM71526.1 - 0.033 14.0 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain zf-H2C2_2 PF13465.6 KFM71531.1 - 1.7e-46 154.6 56.3 3.7e-08 33.4 0.4 9.5 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71531.1 - 2.4e-39 131.6 67.2 2.8e-06 27.5 1.8 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71531.1 - 5.2e-30 101.5 62.6 0.00024 21.7 1.7 9.3 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM71531.1 - 5.3e-21 74.0 41.2 0.01 15.6 0.4 9.4 9 0 0 9 9 9 8 C2H2-type zinc-finger domain zf-met PF12874.7 KFM71531.1 - 7.1e-21 73.9 63.6 0.00021 21.5 1.1 9.3 10 1 0 10 10 9 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM71531.1 - 5.4e-12 45.7 41.4 0.029 14.7 0.2 8.6 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM71531.1 - 6.1e-10 38.7 53.0 0.0029 17.3 1.6 8.6 9 0 0 9 9 9 4 zinc-finger C2H2-type BolA PF01722.18 KFM71531.1 - 4.7e-09 36.4 6.0 0.18 12.1 0.2 5.9 1 1 4 5 5 5 2 BolA-like protein zf-MYST PF17772.1 KFM71531.1 - 1.4e-06 27.8 37.1 0.025 14.2 0.2 7.9 2 1 6 8 8 8 4 MYST family zinc finger domain zf-C2HC_2 PF13913.6 KFM71531.1 - 8.7e-06 25.5 30.0 0.12 12.4 0.1 8.3 9 0 0 9 9 9 2 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM71531.1 - 3.9e-05 23.4 34.1 1.7 8.5 0.1 7.9 4 2 4 8 8 8 3 C2H2 type zinc-finger (1 copy) Tox-HNH-HHH PF15637.6 KFM71531.1 - 0.00027 21.0 0.6 9.1 6.5 0.0 4.3 1 1 4 6 6 6 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_6 PF13912.6 KFM71531.1 - 0.00043 20.2 49.3 0.13 12.3 0.6 9.0 8 1 0 8 8 8 3 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM71531.1 - 0.0072 16.4 29.0 1 9.4 0.2 7.9 6 2 2 8 8 8 1 Sec23/Sec24 zinc finger Baculo_IE-1 PF05290.11 KFM71531.1 - 0.022 14.7 29.9 0.13 12.2 5.7 6.0 1 1 3 4 4 4 0 Baculovirus immediate-early protein (IE-0) zf-DBF PF07535.12 KFM71531.1 - 0.033 14.3 36.2 8.5 6.6 0.4 8.2 8 0 0 8 8 8 0 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM71531.1 - 0.17 12.0 38.3 0.2 11.8 3.2 4.0 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM71531.1 - 0.26 11.5 30.2 4.5 7.5 0.2 7.7 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Zf_RING PF16744.5 KFM71531.1 - 0.34 11.1 37.6 7.8 6.7 0.7 7.4 1 1 4 6 6 6 0 KIAA1045 RING finger GAGA PF09237.11 KFM71531.1 - 0.39 10.6 16.7 14 5.6 0.2 6.4 2 1 4 7 7 7 0 GAGA factor zinc_ribbon_15 PF17032.5 KFM71531.1 - 3.3 8.5 37.1 1 10.1 2.6 4.9 1 1 1 3 3 3 0 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM71531.1 - 6 7.3 57.5 3.1 8.2 14.8 7.6 1 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-Dof PF02701.15 KFM71531.1 - 7.3 6.8 24.3 26 5.0 0.1 6.6 1 1 5 6 6 6 0 Dof domain, zinc finger Chorion_3 PF05387.11 KFM71532.1 - 1 8.9 5.9 1.1 8.8 5.9 1.0 1 0 0 1 1 1 0 Chorion family 3 Peptidase_M14 PF00246.24 KFM71537.1 - 2.5e-82 277.0 0.0 2.9e-82 276.7 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFM71537.1 - 0.0031 17.9 0.1 0.0078 16.6 0.1 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Ig_3 PF13927.6 KFM71538.1 - 7.6e-16 58.5 7.5 2.6e-09 37.6 0.2 3.5 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM71538.1 - 5.9e-11 42.3 0.3 2.7e-09 37.0 0.1 2.7 2 0 0 2 2 2 1 Immunoglobulin I-set domain F5_F8_type_C PF00754.25 KFM71538.1 - 1.8e-10 41.0 0.0 3.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain ig PF00047.25 KFM71538.1 - 1.7e-09 37.7 4.4 5.3e-05 23.3 0.3 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM71538.1 - 2.6e-09 37.3 4.9 4.1e-06 27.0 0.2 2.7 2 0 0 2 2 2 2 Immunoglobulin domain CUB PF00431.20 KFM71538.1 - 4.8e-09 36.5 0.1 2.9e-06 27.6 0.0 2.8 2 0 0 2 2 2 2 CUB domain Sad1_UNC PF07738.13 KFM71538.1 - 0.0044 17.0 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ig_5 PF16681.5 KFM71538.1 - 0.015 15.7 0.2 0.051 14.0 0.2 1.9 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 KFM71538.1 - 0.026 14.3 0.1 0.11 12.3 0.1 2.1 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 V-set PF07686.17 KFM71538.1 - 0.038 14.2 3.7 0.11 12.7 0.2 3.2 3 1 0 3 3 3 0 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM71538.1 - 0.14 12.5 2.8 0.19 12.0 0.3 2.6 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Ras PF00071.22 KFM71540.1 - 2.7e-34 118.1 0.0 3.7e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM71540.1 - 1.8e-21 76.5 0.1 2.6e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM71540.1 - 1.3e-07 31.3 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM71540.1 - 9.6e-05 22.0 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DNA_pol3_delta2 PF13177.6 KFM71541.1 - 0.072 12.9 0.2 0.078 12.8 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Trypsin PF00089.26 KFM71542.1 - 9.9e-27 94.2 0.0 2.5e-26 92.8 0.0 1.8 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 KFM71544.1 - 4e-27 94.1 44.1 1.9e-11 43.9 12.0 3.1 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A DVL PF08137.12 KFM71545.1 - 0.013 15.3 0.7 0.024 14.5 0.7 1.3 1 0 0 1 1 1 0 DVL family Ldl_recept_a PF00057.18 KFM71546.1 - 5.2e-14 52.2 28.5 8.8e-08 32.2 5.3 2.3 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Phytochelatin PF05023.14 KFM71547.1 - 0.1 11.8 0.7 0.17 11.0 0.7 1.3 1 1 0 1 1 1 0 Phytochelatin synthase DUF1053 PF06327.14 KFM71548.1 - 0.073 13.6 0.7 0.36 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) DUF4006 PF13179.6 KFM71548.1 - 0.12 12.3 0.5 0.32 10.9 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF2171 PF09939.9 KFM71548.1 - 0.13 12.6 0.2 19 5.6 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2171) FinO_N PF12602.8 KFM71548.1 - 0.18 12.1 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Fertility inhibition protein N terminal TarH PF02203.15 KFM71548.1 - 0.42 10.5 0.8 0.71 9.8 0.2 1.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue STT3 PF02516.14 KFM71549.1 - 1.6e-23 83.4 2.3 1.8e-23 83.2 2.3 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PhoR PF11808.8 KFM71550.1 - 0.034 14.6 0.0 0.046 14.1 0.0 1.3 1 1 0 1 1 1 0 Phosphate regulon sensor protein PhoR NhaB PF06450.12 KFM71550.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial Na+/H+ antiporter B (NhaB) MHYT PF03707.16 KFM71551.1 - 6.4 7.0 7.9 42 4.4 7.0 2.3 1 1 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF4371 PF14291.6 KFM71552.1 - 5.3e-10 39.4 0.0 9.3e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DDE_3 PF13358.6 KFM71553.1 - 6e-09 35.8 0.0 9.5e-09 35.2 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M20 PF01546.28 KFM71554.1 - 1.4e-34 119.7 0.0 3.3e-34 118.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFM71554.1 - 4.2e-17 62.0 0.0 7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFM71554.1 - 0.002 17.9 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 HTH_48 PF17906.1 KFM71555.1 - 0.0024 18.0 0.2 0.0074 16.4 0.1 1.9 2 0 0 2 2 2 1 HTH domain in Mos1 transposase Transposase_1 PF01359.18 KFM71556.1 - 0.0086 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) Ank_2 PF12796.7 KFM71557.1 - 1.5e-19 70.4 2.6 1.1e-10 41.9 1.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM71557.1 - 8.6e-16 58.1 1.1 2e-07 31.4 0.4 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM71557.1 - 1.2e-14 54.2 4.9 3.7e-06 27.1 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFM71557.1 - 2e-14 53.3 0.4 1.9e-05 24.9 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFM71557.1 - 3.1e-13 48.6 1.9 7.6e-05 22.8 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Big_1 PF02369.16 KFM71557.1 - 0.16 12.0 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Adenyl_cycl_N PF12633.7 KFM71558.1 - 0.0024 17.8 0.1 0.0027 17.6 0.1 1.1 1 0 0 1 1 1 1 Adenylate cyclase NT domain Nucleoporin2 PF04096.14 KFM71558.1 - 0.03 14.5 0.2 0.037 14.2 0.2 1.1 1 0 0 1 1 1 0 Nucleoporin autopeptidase SAE2 PF08573.10 KFM71559.1 - 1.9e-06 29.0 1.0 1.9e-06 29.0 1.0 6.0 4 2 1 5 5 5 2 DNA repair protein endonuclease SAE2/CtIP C-terminus ObR_Ig PF18589.1 KFM71559.1 - 0.21 12.0 0.1 0.21 12.0 0.1 4.1 3 0 0 3 3 3 0 Obesity receptor immunoglobulin like domain DDE_3 PF13358.6 KFM71560.1 - 1.6e-10 40.9 0.0 1.8e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_A17 PF05380.13 KFM71562.1 - 2.8e-55 186.7 0.1 6.5e-55 185.6 0.1 1.7 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 KFM71562.1 - 5e-36 123.9 2.5 7.1e-36 123.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM71562.1 - 1.7e-16 60.4 0.1 7.1e-16 58.4 0.1 2.1 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF5641 PF18701.1 KFM71562.1 - 8.5e-15 54.7 2.4 2e-14 53.5 1.0 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5641) HTH_Tnp_Tc3_2 PF01498.18 KFM71562.1 - 2e-13 50.4 1.8 6e-13 48.8 1.8 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71562.1 - 3.5e-13 49.5 0.0 2e-11 43.8 0.0 2.7 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.26 KFM71562.1 - 3.1e-12 46.7 0.0 1.1e-10 41.7 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM71562.1 - 6e-12 45.5 0.2 2.4e-11 43.5 0.2 2.2 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 KFM71562.1 - 1.1e-09 38.2 1.3 3e-09 36.7 0.2 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SSF PF00474.17 KFM71562.1 - 3.9e-08 32.6 3.1 6.6e-08 31.8 3.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family BBIP10 PF14777.6 KFM71562.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 RESP18 PF14948.6 KFM71562.1 - 0.037 14.3 0.2 0.12 12.7 0.2 1.8 1 0 0 1 1 1 0 RESP18 domain PBS_linker_poly PF00427.21 KFM71562.1 - 0.097 12.7 0.2 2.8 8.0 0.1 2.7 2 0 0 2 2 2 0 Phycobilisome Linker polypeptide Asp_protease_2 PF13650.6 KFM71562.1 - 0.098 13.3 0.0 0.37 11.5 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 KFM71562.1 - 0.13 12.5 0.7 0.34 11.2 0.2 2.1 2 0 0 2 2 1 0 H2C2 zinc finger HTH_32 PF13565.6 KFM71562.1 - 5.2 7.7 6.1 5.6 7.7 2.3 2.8 2 0 0 2 2 2 0 Homeodomain-like domain GST_C_3 PF14497.6 KFM71563.1 - 4.8e-17 62.0 0.2 7.7e-17 61.3 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFM71563.1 - 6.4e-12 45.7 0.2 2.3e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFM71563.1 - 1.4e-10 41.2 0.1 2.1e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM71563.1 - 5.5e-07 29.5 0.2 9.8e-07 28.7 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFM71563.1 - 0.0054 16.5 0.4 0.028 14.2 0.4 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM71563.1 - 0.032 14.6 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RCC_reductase PF06405.11 KFM71563.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) PDZ PF00595.24 KFM71564.1 - 1.6e-42 143.7 5.5 1.6e-14 54.0 0.1 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFM71564.1 - 3.4e-24 84.5 0.9 1.6e-10 40.7 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFM71564.1 - 3.7e-15 56.0 6.5 3.7e-07 30.4 0.0 3.4 2 1 1 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 KFM71564.1 - 5.9e-14 52.1 0.2 6.3e-13 48.8 0.2 2.4 2 0 0 2 2 2 1 Guanylate kinase SH3_2 PF07653.17 KFM71564.1 - 3.8e-11 42.5 0.7 1.7e-10 40.4 0.5 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFM71564.1 - 0.015 14.9 0.0 0.045 13.4 0.0 1.9 1 0 0 1 1 1 0 SH3 domain Glyco_transf_10 PF00852.19 KFM71565.1 - 1.8e-38 132.0 1.0 2.1e-38 131.8 1.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term SF3A3 PF16837.5 KFM71565.1 - 0.078 13.5 0.1 0.078 13.5 0.1 1.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 PBD PF00786.28 KFM71566.1 - 7.3e-07 29.4 0.5 1.1e-06 28.9 0.5 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain zf-CDGSH PF09360.10 KFM71567.1 - 1.5e-19 69.9 2.5 9.1e-11 41.8 0.1 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type TSP_NTD PF17804.1 KFM71568.1 - 0.0083 16.4 0.0 0.0099 16.2 0.0 1.0 1 0 0 1 1 1 1 Tail specific protease N-terminal domain FAM104 PF15434.6 KFM71569.1 - 2.8e-06 27.8 2.3 5.6e-06 26.9 2.3 1.5 1 1 0 1 1 1 1 Family 104 WRW PF10206.9 KFM71570.1 - 1e-44 151.0 0.4 1.2e-44 150.8 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f F1F0-ATPsyn_F PF10791.9 KFM71570.1 - 2e-05 25.0 0.0 2.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi DDE_3 PF13358.6 KFM71571.1 - 0.00016 21.4 0.0 0.00016 21.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Actin PF00022.19 KFM71572.1 - 1e-149 498.6 0.0 3.4e-149 496.9 0.0 1.7 1 1 0 1 1 1 1 Actin BAR PF03114.18 KFM71574.1 - 1.1e-13 51.4 3.1 1.3e-13 51.2 3.1 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KFM71574.1 - 0.0052 16.0 1.1 0.0058 15.8 1.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF1110 PF06533.12 KFM71574.1 - 0.011 15.7 0.3 0.011 15.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) YojJ PF10372.9 KFM71574.1 - 0.016 15.3 0.5 0.028 14.5 0.2 1.6 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus BAR PF03114.18 KFM71575.1 - 1.5e-15 57.5 1.1 1.6e-15 57.4 1.1 1.0 1 0 0 1 1 1 1 BAR domain Nab1 PF04902.12 KFM71575.1 - 0.036 14.5 0.0 0.052 14.0 0.0 1.2 1 1 0 1 1 1 0 Conserved region in Nab1 zf-C2H2_4 PF13894.6 KFM71576.1 - 0.00051 20.7 47.9 0.057 14.3 0.3 7.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM71576.1 - 0.00054 20.3 43.2 0.16 12.5 2.8 6.8 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-met PF12874.7 KFM71576.1 - 0.025 15.0 25.4 0.27 11.7 1.2 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Astacin PF01400.24 KFM71577.1 - 5.5e-52 176.2 0.0 6.5e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) KASH_CCD PF14662.6 KFM71578.1 - 0.0027 17.6 23.3 0.0027 17.6 23.3 2.1 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH Prominin PF05478.11 KFM71578.1 - 0.49 8.3 14.6 0.61 8.0 14.6 1.3 1 0 0 1 1 1 0 Prominin Mod_r PF07200.13 KFM71578.1 - 1.1 9.3 39.5 0.057 13.5 12.4 2.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein mCpol PF18182.1 KFM71578.1 - 1.3 9.4 5.3 0.59 10.5 0.6 2.5 2 1 0 2 2 2 0 minimal CRISPR polymerase domain Cnn_1N PF07989.11 KFM71578.1 - 2.8 8.2 35.0 0.15 12.3 2.8 4.6 1 1 4 5 5 5 0 Centrosomin N-terminal motif 1 Fez1 PF06818.15 KFM71578.1 - 4.9 7.5 35.9 4.1 7.8 7.3 2.2 1 1 1 2 2 2 0 Fez1 Lzipper-MIP1 PF14389.6 KFM71578.1 - 5.7 7.3 33.5 1.2 9.4 4.0 4.4 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.6 KFM71579.1 - 0.058 12.7 17.8 0.52 9.6 6.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BST2 PF16716.5 KFM71579.1 - 0.081 13.5 14.1 0.3 11.7 2.1 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 MitMem_reg PF13012.6 KFM71579.1 - 0.093 13.1 2.4 0.15 12.5 2.4 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF659 PF04937.15 KFM71579.1 - 0.13 12.1 0.4 0.13 12.1 0.4 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF 659) Nrap_D6 PF17407.2 KFM71579.1 - 0.16 12.2 1.4 0.39 10.9 1.4 1.7 1 1 0 1 1 1 0 Nrap protein domain 6 DUF3450 PF11932.8 KFM71579.1 - 0.58 9.4 12.8 0.31 10.3 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 KFM71579.1 - 0.67 9.0 14.6 0.78 8.8 14.6 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KFM71579.1 - 0.69 10.0 9.1 1.4 9.0 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YbaB_DNA_bd PF02575.16 KFM71579.1 - 0.69 10.2 6.0 12 6.3 1.0 2.7 2 1 0 2 2 2 0 YbaB/EbfC DNA-binding family Bap31_Bap29_C PF18035.1 KFM71579.1 - 0.75 9.8 15.5 0.33 11.0 0.8 3.2 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1515 PF07439.11 KFM71579.1 - 1.2 9.2 7.0 0.53 10.3 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF4375 PF14300.6 KFM71579.1 - 6.2 7.1 8.4 2.3 8.5 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) FMO-like PF00743.19 KFM71581.1 - 3.4e-83 279.9 0.0 4.1e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM71581.1 - 0.00042 19.7 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RT_RNaseH PF17917.1 KFM71582.1 - 4.7e-34 116.8 0.0 1.2e-33 115.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KFM71582.1 - 1.5e-33 114.8 0.0 3.7e-33 113.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM71582.1 - 6.5e-27 94.5 0.3 1.6e-26 93.2 0.3 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM71582.1 - 3.2e-20 72.5 0.0 8.2e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM71582.1 - 7.9e-19 67.5 0.2 1.8e-18 66.4 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM71582.1 - 1.1e-06 28.7 0.1 2.9e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 KFM71582.1 - 4.7e-05 23.3 1.8 0.00018 21.4 1.8 2.1 1 0 0 1 1 1 1 Zinc knuckle SCAN PF02023.17 KFM71582.1 - 0.00037 20.2 0.0 0.0015 18.3 0.0 2.1 1 0 0 1 1 1 1 SCAN domain gag-asp_proteas PF13975.6 KFM71582.1 - 0.0011 19.4 0.0 0.003 18.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KFM71582.1 - 0.0026 18.0 0.0 0.075 13.4 0.0 2.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Phage_sheath_1C PF17482.2 KFM71582.1 - 0.0031 17.5 0.2 0.018 15.0 0.1 2.4 2 0 0 2 2 2 1 Phage tail sheath C-terminal domain DUF1667 PF07892.11 KFM71582.1 - 0.027 14.5 1.0 0.09 12.8 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) rve_3 PF13683.6 KFM71582.1 - 0.042 13.6 0.0 0.042 13.6 0.0 3.2 3 0 0 3 3 3 0 Integrase core domain DUF5384 PF17358.2 KFM71582.1 - 0.055 13.5 14.1 0.12 12.4 14.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5384) DDE_Tnp_IS66_C PF13817.6 KFM71582.1 - 0.074 13.3 0.0 12 6.2 0.0 3.5 3 0 0 3 3 3 0 IS66 C-terminal element Asp_protease_2 PF13650.6 KFM71582.1 - 0.092 13.4 0.0 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease HET-s_218-289 PF11558.8 KFM71582.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Het-s 218-289 PLAT PF01477.23 KFM71583.1 - 3.7e-16 59.7 0.1 9.5e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain DUF2956 PF11169.8 KFM71583.1 - 0.021 15.0 1.9 0.047 13.9 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) LAP1C PF05609.12 KFM71583.1 - 0.099 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PKD_channel PF08016.12 KFM71584.1 - 7.7e-80 268.6 2.3 8.7e-80 268.5 2.3 1.0 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFM71584.1 - 9.3e-06 25.0 12.1 5.5e-05 22.5 12.1 2.0 1 1 0 1 1 1 1 Ion transport protein KASH PF10541.9 KFM71584.1 - 0.12 12.6 1.0 0.47 10.8 1.0 2.0 1 0 0 1 1 1 0 Nuclear envelope localisation domain Kelch_4 PF13418.6 KFM71585.1 - 1.1e-25 89.4 11.6 1.3e-08 34.7 0.9 5.3 3 1 2 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFM71585.1 - 6e-25 87.0 14.2 1.2e-08 35.1 0.3 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM71585.1 - 8.2e-24 83.0 7.1 1.3e-06 28.5 0.0 4.9 3 1 1 4 4 4 4 Kelch motif Kelch_5 PF13854.6 KFM71585.1 - 2.7e-22 78.3 0.7 3.2e-05 23.8 0.0 4.9 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 KFM71585.1 - 1.2e-20 72.8 3.2 1.5e-07 30.9 0.7 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 KFM71585.1 - 5.1e-18 64.3 6.5 6e-07 29.2 0.2 5.1 4 1 0 4 4 4 3 Kelch motif F-box-like PF12937.7 KFM71585.1 - 2.2e-08 33.8 0.1 5.6e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM71585.1 - 1.1e-05 25.2 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain GDP_Man_Dehyd PF16363.5 KFM71586.1 - 2.3e-57 194.9 0.0 2.7e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFM71586.1 - 1.9e-50 171.6 0.0 2.4e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM71586.1 - 4.6e-17 61.9 0.0 4.5e-16 58.7 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFM71586.1 - 4.7e-13 48.9 0.0 2e-11 43.6 0.0 2.4 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFM71586.1 - 2.6e-10 39.9 0.0 3.9e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFM71586.1 - 2e-07 31.1 0.0 9.4e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFM71586.1 - 4.7e-05 22.7 0.0 0.00041 19.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KFM71586.1 - 0.0015 18.1 0.0 0.0081 15.7 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 KFM71586.1 - 0.0095 15.9 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 1 KR domain DapB_N PF01113.20 KFM71586.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ATP-synt_F6 PF05511.11 KFM71587.1 - 3.4e-26 91.5 0.2 4.1e-26 91.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 Amidohydro_3 PF07969.11 KFM71588.1 - 1.3e-19 71.0 1.7 3.1e-12 46.7 0.1 2.5 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KFM71588.1 - 6.4e-16 58.6 2.3 4.7e-15 55.7 2.3 2.0 1 1 0 1 1 1 1 Amidohydrolase family DUF3363 PF11843.8 KFM71588.1 - 0.028 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) Na_H_Exchanger PF00999.21 KFM71589.1 - 2.7e-15 56.0 0.9 3.3e-15 55.8 0.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1325 PF07039.11 KFM71589.1 - 0.035 14.2 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 SGF29 tudor-like domain DUF3682 PF12446.8 KFM71589.1 - 1.7 9.1 9.6 3.3 8.2 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) 7tm_7 PF08395.12 KFM71590.1 - 7.2e-11 41.9 13.5 1e-10 41.4 13.5 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor Trehalose_recp PF06151.13 KFM71590.1 - 9e-09 34.4 11.1 1.1e-08 34.1 11.1 1.0 1 0 0 1 1 1 1 Trehalose receptor 7tm_6 PF02949.20 KFM71590.1 - 0.00029 20.0 6.5 0.00029 20.0 6.5 1.7 1 1 0 2 2 2 1 7tm Odorant receptor HTH_Tnp_Tc3_2 PF01498.18 KFM71591.1 - 2.2e-16 59.8 2.7 3.9e-16 59.0 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71591.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM71592.1 - 2.8e-13 49.9 0.0 4.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Crp_2 PF13545.6 KFM71592.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PAX PF00292.18 KFM71592.1 - 0.043 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain MarR_2 PF12802.7 KFM71592.1 - 0.095 12.6 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 MarR family DUF5456 PF17539.2 KFM71592.1 - 0.21 11.4 0.4 16 5.3 0.1 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5456) HTH_32 PF13565.6 KFM71592.1 - 0.52 11.0 5.5 0.39 11.4 2.5 2.4 2 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71593.1 - 5.1e-16 58.7 3.5 6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71593.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71593.1 - 2.2e-07 30.5 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71593.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71593.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71594.1 - 4.1e-16 59.0 3.2 6e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71594.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71594.1 - 5.8e-07 29.2 1.5 1.6e-06 27.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71594.1 - 0.018 14.8 0.5 0.05 13.4 0.5 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM71594.1 - 1.4 9.5 15.9 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ion_trans PF00520.31 KFM71595.1 - 5.9e-09 35.5 0.2 6.3e-09 35.4 0.2 1.0 1 0 0 1 1 1 1 Ion transport protein Carb_anhydrase PF00194.21 KFM71596.1 - 1.3e-35 123.2 0.0 1.5e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF4371 PF14291.6 KFM71597.1 - 6.1e-06 26.0 0.0 7.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KFM71597.1 - 0.0038 17.1 0.3 0.0045 16.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) COesterase PF00135.28 KFM71598.1 - 1.6e-26 93.3 0.4 2.4e-26 92.7 0.4 1.3 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KFM71599.1 - 1.1e-16 60.9 0.0 1.1e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Neur_chan_LBD PF02931.23 KFM71602.1 - 7.7e-44 149.7 3.1 9.4e-44 149.4 3.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain AHJR-like PF18743.1 KFM71602.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 REase_AHJR-like DEAD PF00270.29 KFM71603.1 - 1.8e-39 135.3 0.0 3.3e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM71603.1 - 2.7e-29 101.7 0.0 1.1e-28 99.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM71603.1 - 5.7e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KFM71603.1 - 0.0015 18.5 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 Helicase SNF2_N PF00176.23 KFM71603.1 - 0.0071 15.1 0.0 0.018 13.8 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 KFM71603.1 - 0.031 14.6 0.0 0.29 11.4 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 KFM71603.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cupin_8 PF13621.6 KFM71604.1 - 0.00015 21.6 0.3 0.014 15.1 0.1 2.1 1 1 1 2 2 2 2 Cupin-like domain DUF5388 PF17363.2 KFM71604.1 - 0.099 12.9 0.5 0.26 11.5 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5388) FHA PF00498.26 KFM71605.1 - 3.6e-15 56.1 0.0 5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM71605.1 - 4.5e-08 33.3 0.1 1.6e-06 28.3 0.1 2.0 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain NIBRIN_BRCT_II PF16508.5 KFM71606.1 - 2.5e-21 76.2 0.0 6.2e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein Nbs1_C PF08599.10 KFM71606.1 - 7.7e-07 29.2 0.0 2.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 DNA damage repair protein Nbs1 BRCT PF00533.26 KFM71606.1 - 0.0016 18.8 0.1 0.022 15.1 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KFM71606.1 - 0.0029 17.4 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KFM71606.1 - 0.043 13.8 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain DUF3641 PF12345.8 KFM71607.1 - 0.0016 18.5 0.6 0.0016 18.5 0.6 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF3641) zf-CCHC_3 PF13917.6 KFM71607.1 - 6.2 6.9 17.3 12 6.0 10.4 2.7 1 1 1 2 2 2 0 Zinc knuckle MCU PF04678.13 KFM71607.1 - 8.7 6.4 6.7 0.81 9.8 0.5 2.3 3 0 0 3 3 3 0 Mitochondrial calcium uniporter HEAT PF02985.22 KFM71608.1 - 6.8e-14 50.8 0.1 0.00022 21.2 0.0 5.3 6 0 0 6 6 4 2 HEAT repeat HEAT_EZ PF13513.6 KFM71608.1 - 2.2e-10 40.8 0.0 0.0015 18.9 0.0 4.1 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KFM71608.1 - 3.1e-06 27.3 4.1 0.17 11.9 0.1 3.9 2 2 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM71608.1 - 6.7e-06 26.4 0.0 0.22 11.9 0.0 2.9 2 1 1 3 3 3 3 HEAT repeats RIX1 PF08167.12 KFM71608.1 - 2.2e-05 24.3 0.1 0.14 11.9 0.0 2.9 3 1 0 3 3 3 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 KFM71608.1 - 9.3e-05 23.0 0.0 29 5.4 0.0 4.6 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KFM71608.1 - 0.00039 19.7 1.2 0.47 9.5 0.0 3.6 1 1 2 3 3 3 2 RNAPII transcription regulator C-terminal Cnd3 PF12719.7 KFM71608.1 - 0.00062 19.0 0.1 1 8.5 0.0 2.8 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KFM71608.1 - 0.0012 18.8 0.0 5.3 7.2 0.0 3.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat CARD_2 PF16739.5 KFM71608.1 - 0.025 14.6 0.4 2.5 8.2 0.1 3.5 4 0 0 4 4 4 0 Caspase recruitment domain CLASP_N PF12348.8 KFM71608.1 - 0.025 14.1 0.2 19 4.7 0.0 3.8 3 2 0 3 3 3 0 CLASP N terminal Dopey_N PF04118.14 KFM71608.1 - 0.034 13.2 0.1 0.11 11.6 0.1 2.0 1 1 1 2 2 2 0 Dopey, N-terminal Ipi1_N PF12333.8 KFM71608.1 - 0.079 13.6 0.0 0.51 11.0 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation HTH_Tnp_Tc3_2 PF01498.18 KFM71609.1 - 4.9e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71609.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71609.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71609.1 - 0.0025 17.6 0.6 0.0076 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71609.1 - 1.9 9.1 15.6 0.12 13.0 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain Sulfatase PF00884.23 KFM71610.1 - 7.3e-14 51.9 0.0 1.3e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF3740 PF12548.8 KFM71613.1 - 6.3e-05 23.4 0.2 7.2e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 Sulfatase protein Lsr2 PF11774.8 KFM71614.1 - 0.09 12.9 0.3 0.15 12.3 0.3 1.3 1 0 0 1 1 1 0 Lsr2 DUF659 PF04937.15 KFM71615.1 - 0.00012 22.0 0.2 0.00046 20.1 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM71615.1 - 0.00019 21.2 0.3 0.0009 18.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-BED PF02892.15 KFM71615.1 - 0.0042 17.1 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 BED zinc finger DUF4772 PF15997.5 KFM71616.1 - 1.1e-29 103.4 0.2 2e-28 99.3 0.2 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4772) FOXP-CC PF16159.5 KFM71616.1 - 0.00079 20.0 0.3 0.0022 18.6 0.3 1.7 1 0 0 1 1 1 1 FOXP coiled-coil domain DUF3678 PF12435.8 KFM71616.1 - 0.035 13.5 2.8 0.2 11.1 2.8 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) zf-C2H2_4 PF13894.6 KFM71616.1 - 4.5 8.4 8.3 0.2 12.6 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ig_mannosidase PF17753.1 KFM71617.1 - 0.00042 20.0 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 KFM71618.1 - 0.025 13.7 0.1 0.17 11.0 0.0 2.2 2 1 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain IPPT PF01715.17 KFM71619.1 - 8.4e-63 212.2 0.1 1.9e-62 211.0 0.1 1.5 1 1 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.8 KFM71619.1 - 1e-08 35.3 0.8 2.5e-08 34.0 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM71619.1 - 2.2e-07 31.0 1.5 1.1e-06 28.8 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type AAA_18 PF13238.6 KFM71619.1 - 2.1e-06 28.3 0.1 0.007 16.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF3449 PF11931.8 KFM71619.1 - 1.2e-05 25.2 0.0 3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) IPT PF01745.16 KFM71619.1 - 2e-05 24.1 0.1 5.9e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 KFM71619.1 - 4.6e-05 23.6 0.1 0.024 14.8 0.0 2.9 3 1 0 3 3 3 1 AAA domain SKI PF01202.22 KFM71619.1 - 0.022 14.9 0.0 7.1 6.7 0.1 3.2 3 0 0 3 3 3 0 Shikimate kinase zf-C2H2_2 PF12756.7 KFM71619.1 - 0.037 14.4 0.2 0.08 13.3 0.2 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_22 PF13401.6 KFM71619.1 - 0.041 14.2 0.1 0.15 12.3 0.1 2.0 1 1 1 2 2 2 0 AAA domain zf-DBF PF07535.12 KFM71619.1 - 0.18 11.9 1.3 0.31 11.2 0.2 2.0 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2 PF00096.26 KFM71619.1 - 0.42 11.2 2.2 0.38 11.3 0.2 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type IF-2 PF11987.8 KFM71621.1 - 9.7e-30 102.8 0.1 3.1e-29 101.2 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KFM71621.1 - 0.00087 19.6 0.2 0.39 11.2 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu domain 2 DUF1744 PF08490.12 KFM71621.1 - 0.019 13.6 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) GTP_EFTU PF00009.27 KFM71622.1 - 3.2e-29 101.9 4.8 4.4e-27 94.9 4.8 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM71622.1 - 8.8e-12 45.1 0.0 1e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFM71622.1 - 1.6e-05 24.4 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFM71622.1 - 0.00013 22.1 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KFM71622.1 - 0.00042 19.9 0.1 0.001 18.7 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 KFM71622.1 - 0.0012 18.5 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFM71622.1 - 0.0021 17.5 0.2 0.0057 16.1 0.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KFM71622.1 - 0.0034 17.4 0.0 0.68 10.0 0.0 2.2 1 1 1 2 2 2 2 Dynamin family SIS_2 PF13580.6 KFM71622.1 - 0.03 14.4 0.4 0.23 11.5 0.2 1.8 1 1 1 2 2 2 0 SIS domain PduV-EutP PF10662.9 KFM71622.1 - 0.046 13.5 0.1 0.1 12.4 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KFM71622.1 - 0.095 12.6 2.6 3.9 7.3 0.1 2.3 1 1 1 2 2 2 0 RsgA GTPase DFP PF04127.15 KFM71624.1 - 5.4e-21 75.3 0.0 3.3e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein LRR_8 PF13855.6 KFM71625.1 - 2.2e-05 24.1 7.0 0.0086 15.8 0.0 3.9 3 1 2 5 5 5 3 Leucine rich repeat Beta_helix PF13229.6 KFM71625.1 - 0.0039 17.1 8.4 0.012 15.5 7.5 2.0 1 1 0 1 1 1 1 Right handed beta helix region Toxin_35 PF10530.9 KFM71625.1 - 0.075 13.0 1.1 0.16 12.0 1.1 1.5 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold SSF PF00474.17 KFM71626.1 - 8.5e-14 51.2 2.5 1.3e-13 50.6 2.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family SOUL PF04832.12 KFM71627.1 - 2.7e-11 43.9 0.0 3.4e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein SSF PF00474.17 KFM71628.1 - 7.7e-19 67.8 7.4 1.1e-18 67.4 7.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3042 PF11240.8 KFM71628.1 - 0.27 11.3 0.0 0.27 11.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) DUF5359 PF17313.2 KFM71629.1 - 0.089 12.8 3.7 0.12 12.4 3.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5359) zf-A20 PF01754.16 KFM71631.1 - 0.0067 16.3 2.9 0.0067 16.3 2.9 2.5 2 0 0 2 2 2 2 A20-like zinc finger OCRE PF17780.1 KFM71632.1 - 3e-18 65.6 19.2 6.2e-18 64.6 19.2 1.6 1 0 0 1 1 1 1 OCRE domain G-patch PF01585.23 KFM71632.1 - 5.1e-13 48.7 7.5 9.8e-13 47.8 7.5 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KFM71632.1 - 2.5e-11 43.2 0.0 1.5e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KFM71632.1 - 4e-10 39.6 1.4 1.7e-09 37.6 1.4 2.2 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 KFM71632.1 - 5.6e-06 25.6 4.5 1.1e-05 24.6 4.5 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C2H2_jaz PF12171.8 KFM71632.1 - 0.074 13.4 0.6 0.16 12.3 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DZR PF12773.7 KFM71632.1 - 0.12 12.4 2.3 0.18 11.9 1.1 1.8 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_11 PF16622.5 KFM71632.1 - 0.22 11.3 2.6 0.27 11.0 0.3 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFM71632.1 - 1.8 9.0 3.9 0.7 10.3 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) WD40 PF00400.32 KFM71634.1 - 1.7e-19 69.8 6.9 4.7e-07 30.4 0.3 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM71634.1 - 1.6e-13 50.7 0.7 0.0079 16.5 0.0 4.1 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM71634.1 - 0.0036 16.0 2.4 0.068 11.8 0.1 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFM71634.1 - 0.011 14.8 1.9 0.057 12.4 1.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TMEM219 PF14940.6 KFM71635.1 - 1.4e-37 129.5 0.0 1.9e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Transmembrane 219 Peptidase_M14 PF00246.24 KFM71636.1 - 2.6e-211 700.3 3.3 1.4e-84 284.3 0.1 6.3 5 1 0 5 5 5 5 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFM71636.1 - 7.9e-49 163.9 6.1 2.1e-12 47.1 0.1 4.5 4 0 0 4 4 4 4 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFM71636.1 - 2.2e-31 107.7 1.4 1.8e-06 27.8 0.2 4.7 4 0 0 4 4 4 4 CarboxypepD_reg-like domain PEGA PF08308.11 KFM71636.1 - 6.6e-13 48.4 1.9 0.0068 16.3 0.0 4.5 4 0 0 4 4 4 3 PEGA domain AstE_AspA PF04952.14 KFM71636.1 - 6.6e-08 32.0 0.5 0.013 14.6 0.0 3.3 3 0 0 3 3 3 2 Succinylglutamate desuccinylase / Aspartoacylase family Big_1 PF02369.16 KFM71636.1 - 0.037 14.0 0.1 19 5.3 0.1 3.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) DUF1533 PF07550.11 KFM71636.1 - 0.039 13.9 0.0 2.7 8.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1533) L_lac_phage_MSP PF06488.11 KFM71636.1 - 0.15 11.3 0.5 6.1 6.0 0.0 3.4 5 0 0 5 5 5 0 Phage tail tube protein DUF3823 PF12866.7 KFM71636.1 - 0.17 12.2 0.4 11 6.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3823) N-terminal domain Sen15 PF09631.10 KFM71637.1 - 6.7e-08 32.7 0.0 1.1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein DUF4481 PF14800.6 KFM71639.1 - 0.0024 17.4 0.0 0.0028 17.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) DDE_3 PF13358.6 KFM71640.1 - 4.8e-12 45.9 0.1 7.8e-12 45.2 0.1 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF4481 PF14800.6 KFM71641.1 - 0.011 15.3 4.9 0.017 14.6 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) HTH_Tnp_Tc3_2 PF01498.18 KFM71642.1 - 9.3e-24 83.5 7.6 1e-15 57.7 0.2 2.7 3 0 0 3 3 3 2 Transposase PAX PF00292.18 KFM71642.1 - 0.0087 16.0 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFM71642.1 - 0.015 15.1 0.4 0.054 13.3 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain RT_RNaseH_2 PF17919.1 KFM71643.1 - 6.2e-37 125.7 0.0 1.6e-36 124.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM71643.1 - 2.9e-35 120.7 0.0 1.3e-34 118.6 0.0 2.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM71643.1 - 9.5e-30 103.8 0.3 2.5e-29 102.4 0.3 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM71643.1 - 1.1e-21 77.3 0.2 4.1e-21 75.4 0.1 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM71643.1 - 1.7e-20 72.8 0.3 4.9e-20 71.4 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM71643.1 - 1.5e-15 57.2 2.2 4.5e-15 55.7 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71643.1 - 5.2e-14 52.2 0.1 3e-12 46.5 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease zf-H2C2 PF09337.10 KFM71643.1 - 8.7e-05 22.7 0.0 0.00083 19.5 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 KFM71643.1 - 0.0002 21.1 0.1 0.00082 19.1 0.1 2.1 1 0 0 1 1 1 1 Integrase core domain Spuma_A9PTase PF03539.14 KFM71643.1 - 0.0032 17.6 3.7 0.004 17.3 0.6 2.7 3 1 0 4 4 4 1 Spumavirus aspartic protease (A9) HTH_32 PF13565.6 KFM71643.1 - 1.4 9.6 4.7 3.2 8.4 1.9 2.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71644.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71644.1 - 1.5e-13 50.8 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 KFM71645.1 - 3.8e-34 116.7 0.1 1e-33 115.3 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM71645.1 - 5e-33 113.5 0.0 1.2e-32 112.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM71645.1 - 6.1e-25 88.0 0.0 1.5e-24 86.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM71645.1 - 9.7e-20 70.9 0.0 2.1e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM71645.1 - 1.4e-15 57.1 0.6 4e-15 55.7 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVP PF00077.20 KFM71645.1 - 1e-06 29.0 0.0 3.1e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 KFM71645.1 - 0.0057 16.4 0.0 0.024 14.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 KFM71645.1 - 0.007 16.4 0.9 0.015 15.4 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 KFM71645.1 - 0.069 13.4 0.3 0.19 11.9 0.3 1.9 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 KFM71645.1 - 0.071 13.7 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM71645.1 - 0.091 13.4 0.0 0.55 10.9 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Ig_3 PF13927.6 KFM71646.1 - 2.6e-16 60.0 0.0 3e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM71646.1 - 1.7e-10 40.8 0.0 2.3e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFM71646.1 - 2e-08 34.3 0.0 2.5e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM71646.1 - 2.6e-08 34.1 0.0 1.4e-05 25.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM71646.1 - 1.2e-05 25.5 0.7 0.057 13.6 0.0 3.7 2 2 0 3 3 3 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM71646.1 - 0.079 12.5 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.6 KFM71647.1 - 1.9e-19 70.1 0.1 2.4e-13 50.4 0.2 3.1 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM71647.1 - 7.8e-17 61.1 0.0 4.5e-10 39.5 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM71647.1 - 3.6e-13 49.6 0.1 3.8e-10 40.0 0.1 3.1 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 KFM71647.1 - 8.9e-10 38.6 0.0 1.2e-06 28.6 0.1 2.6 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFM71647.1 - 2.7e-07 30.7 0.3 0.11 12.7 0.2 3.5 3 1 1 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM71647.1 - 3e-06 26.7 0.0 0.048 13.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Lep_receptor_Ig PF06328.11 KFM71647.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Ig-like C2-type domain Ig_5 PF16681.5 KFM71647.1 - 0.019 15.4 0.0 0.37 11.2 0.0 2.8 3 1 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFM71647.1 - 0.019 15.0 0.0 0.14 12.3 0.0 2.2 2 1 0 2 2 2 0 C17orf99 Ig domain fn3 PF00041.21 KFM71649.1 - 1.2e-10 41.5 0.1 1.7e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Big_1 PF02369.16 KFM71649.1 - 0.11 12.6 0.3 11 6.1 0.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) fn3 PF00041.21 KFM71651.1 - 1.4e-07 31.7 0.1 0.00013 22.3 0.0 2.1 2 0 0 2 2 2 2 Fibronectin type III domain HTH_Tnp_Tc3_2 PF01498.18 KFM71653.1 - 1.9e-16 60.0 1.9 5.5e-16 58.6 1.9 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71653.1 - 1.5e-13 50.7 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71653.1 - 3.5e-07 29.9 1.6 8e-07 28.7 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71653.1 - 0.003 17.3 0.6 0.0086 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71653.1 - 0.035 14.7 1.2 0.035 14.7 1.2 3.1 2 1 1 3 3 3 0 Homeodomain-like domain adh_short PF00106.25 KFM71654.1 - 6.3e-39 133.5 0.0 9.1e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM71654.1 - 1.5e-25 90.2 0.0 2.1e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM71654.1 - 4.8e-05 23.4 0.0 9.5e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Peptidase_C47 PF05543.13 KFM71654.1 - 0.061 12.9 0.3 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 Staphopain peptidase C47 Eno-Rase_NADH_b PF12242.8 KFM71654.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase QVR PF17064.5 KFM71656.1 - 1.4e-06 28.5 9.2 2.9e-06 27.4 9.2 1.5 1 1 0 1 1 1 1 Sleepless protein DUF493 PF04359.14 KFM71656.1 - 0.023 15.3 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF493) zf-HC5HC2H PF13771.6 KFM71656.1 - 0.46 10.8 6.0 1.3 9.3 0.1 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFM71656.1 - 0.7 10.1 8.3 1.8 8.8 0.4 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71658.1 - 2.6e-16 59.6 2.2 4.9e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71658.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease UPF0239 PF06783.11 KFM71659.1 - 5.1e-16 58.6 0.0 7.1e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) MscL PF01741.18 KFM71659.1 - 0.045 14.0 0.0 0.051 13.9 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL HTH_Tnp_Tc3_2 PF01498.18 KFM71660.1 - 5.1e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71660.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71660.1 - 1.8e-06 27.6 1.2 6.1e-06 25.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71660.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71660.1 - 8.3 7.1 15.8 0.13 12.9 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM71661.1 - 5e-16 58.8 0.1 5.8e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71661.1 - 7.8e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71661.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71661.1 - 0.0024 17.6 0.1 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71661.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71661.1 - 0.034 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM71662.1 - 7.6e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71662.1 - 2.2e-15 56.7 0.0 5.7e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71662.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71662.1 - 0.0038 17.0 0.3 0.11 12.3 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71662.1 - 0.018 15.2 0.1 0.063 13.4 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71662.1 - 0.031 14.3 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Lipocalin PF00061.23 KFM71663.1 - 1.9e-07 31.4 0.0 5.1e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFM71663.1 - 0.00088 19.2 0.0 0.037 14.0 0.0 2.4 1 1 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.13 KFM71663.1 - 0.0011 18.9 0.2 0.0018 18.2 0.2 1.4 1 1 0 1 1 1 1 Triabin VDE PF07137.11 KFM71663.1 - 0.061 12.9 0.1 0.14 11.7 0.1 1.6 1 1 0 1 1 1 0 VDE lipocalin domain LINES_C PF14695.6 KFM71665.1 - 0.039 13.4 0.3 0.078 12.4 0.3 1.5 1 0 0 1 1 1 0 Lines C-terminus PseudoU_synth_1 PF01416.20 KFM71666.1 - 5.6e-31 107.2 0.0 4.2e-29 101.2 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Cut8 PF08559.10 KFM71666.1 - 0.0028 17.3 0.1 0.0063 16.2 0.1 1.5 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein RVT_1 PF00078.27 KFM71667.1 - 6.8e-55 186.0 0.0 1e-54 185.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC13_N PF16853.5 KFM71667.1 - 0.031 13.8 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus Transposase_1 PF01359.18 KFM71668.1 - 2.5e-08 33.6 0.1 2.9e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Transposase (partial DDE domain) CoA_transf_3 PF02515.17 KFM71669.1 - 9.1e-77 258.7 0.0 1.3e-76 258.1 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III ABC_tran_CTD PF16326.5 KFM71670.1 - 0.02 15.1 0.9 0.029 14.6 0.1 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Defensin_big PF14862.6 KFM71670.1 - 0.021 15.1 1.7 2.9 8.3 1.7 2.6 1 1 0 1 1 1 0 Big defensin Csm1_N PF18504.1 KFM71670.1 - 0.044 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain AsmA_2 PF13502.6 KFM71670.1 - 0.1 12.1 1.5 1.8 8.1 0.4 2.1 1 1 1 2 2 2 0 AsmA-like C-terminal region SPT16 PF08644.11 KFM71670.1 - 0.13 12.4 0.1 0.79 9.9 0.1 2.0 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) COMM_domain PF07258.14 KFM71670.1 - 2.8 8.1 5.2 1.2 9.3 1.0 2.2 2 1 0 2 2 2 0 COMM domain DUF4745 PF15923.5 KFM71671.1 - 0.029 14.3 0.5 0.034 14.1 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4745) Jnk-SapK_ap_N PF09744.9 KFM71671.1 - 0.049 13.9 5.7 0.053 13.7 5.7 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Ribonuc_red_lgC PF02867.15 KFM71671.1 - 0.092 11.3 3.2 0.099 11.2 3.2 1.0 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain MMPL PF03176.15 KFM71672.1 - 0.73 8.7 2.4 4.5 6.1 0.1 2.0 1 1 1 2 2 2 0 MMPL family HLH PF00010.26 KFM71673.1 - 7.1e-15 54.7 3.5 7.9e-15 54.6 2.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFM71673.1 - 1.6e-13 50.6 0.4 3.8e-13 49.4 0.4 1.7 1 0 0 1 1 1 1 Hairy Orange DUF5600 PF18150.1 KFM71674.1 - 1.4e-42 144.6 2.7 3.1e-42 143.5 2.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KFM71674.1 - 4e-21 74.9 0.1 1.4e-20 73.2 0.1 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 KFM71674.1 - 2e-16 59.6 2.9 2e-16 59.6 2.9 2.0 2 0 0 2 2 2 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 KFM71674.1 - 1.9e-15 57.3 0.0 7e-15 55.5 0.0 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFM71674.1 - 3.9e-08 33.4 0.0 1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KFM71674.1 - 0.00017 20.9 0.2 0.00076 18.9 0.2 2.2 1 0 0 1 1 1 1 EF hand GTP_EFTU PF00009.27 KFM71674.1 - 0.00055 19.5 0.0 0.0015 18.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KFM71674.1 - 0.0038 17.4 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 KFM71674.1 - 0.0097 16.3 0.3 0.038 14.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFM71674.1 - 0.014 15.3 0.2 0.068 13.1 0.2 2.2 1 0 0 1 1 1 0 EF-hand domain Septin PF00735.18 KFM71674.1 - 0.021 14.1 0.3 0.2 10.9 0.0 2.4 2 1 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 KFM71674.1 - 0.024 14.5 0.0 6.4 6.6 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase AAA_28 PF13521.6 KFM71674.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KFM71674.1 - 0.053 13.0 0.0 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 KFM71674.1 - 0.062 13.8 0.4 8 7.0 0.0 3.2 2 1 1 3 3 3 0 AAA domain EF-hand_8 PF13833.6 KFM71674.1 - 0.075 12.9 1.5 3.4 7.6 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KFM71674.1 - 0.12 12.0 1.2 0.23 11.0 0.1 2.1 2 0 0 2 2 2 0 EF hand AIG1 PF04548.16 KFM71674.1 - 0.13 11.6 0.0 0.61 9.4 0.0 2.0 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 KFM71674.1 - 0.16 11.6 0.0 16 5.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4482 PF14818.6 KFM71674.1 - 0.18 12.6 1.6 9.6 7.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) EMI PF07546.13 KFM71675.1 - 9.4 7.1 9.3 1.3 9.8 0.3 3.5 3 0 0 3 3 3 0 EMI domain Pkinase PF00069.25 KFM71676.1 - 2e-30 106.0 0.0 2.5e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM71676.1 - 1.7e-19 70.1 0.0 2.1e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM71676.1 - 2.9e-05 23.1 0.0 3.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM71676.1 - 0.0012 18.8 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM71676.1 - 0.0017 17.8 0.1 0.003 17.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2465 PF10239.9 KFM71677.1 - 7.1e-107 357.4 0.5 8.7e-107 357.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) DUF4682 PF15733.5 KFM71677.1 - 0.24 12.0 1.3 0.85 10.2 1.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4682) COMM_domain PF07258.14 KFM71678.1 - 8.8e-14 51.4 2.2 2.1e-13 50.2 2.2 1.6 1 0 0 1 1 1 1 COMM domain L27 PF02828.16 KFM71678.1 - 0.027 14.2 0.0 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 L27 domain PAX PF00292.18 KFM71679.1 - 0.0022 17.9 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_Tnp_Tc3_2 PF01498.18 KFM71680.1 - 1.9e-17 63.3 1.5 7.3e-16 58.2 2.2 2.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71680.1 - 1.8e-13 50.5 0.0 3.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71680.1 - 3.7e-07 29.8 1.6 8.7e-07 28.6 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71680.1 - 0.0029 17.3 0.5 0.0094 15.7 0.5 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71680.1 - 3.2 8.4 15.6 0.16 12.6 1.9 3.3 2 1 1 3 3 3 0 Homeodomain-like domain L27_2 PF09045.10 KFM71681.1 - 2.1e-08 34.0 2.7 3.5e-08 33.3 2.7 1.4 1 0 0 1 1 1 1 L27_2 L27_1 PF09058.10 KFM71681.1 - 2.8e-05 24.0 0.4 5.9e-05 23.0 0.4 1.6 1 0 0 1 1 1 1 L27_1 PDZ PF00595.24 KFM71681.1 - 0.04 14.3 0.0 0.089 13.2 0.0 1.6 2 0 0 2 2 2 0 PDZ domain LRR_4 PF12799.7 KFM71682.1 - 2.3e-07 31.0 8.1 0.00026 21.3 0.1 4.5 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM71682.1 - 7e-07 28.8 8.6 0.85 9.8 0.0 6.2 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KFM71682.1 - 0.00035 20.7 9.3 3.3 8.6 0.3 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.6 KFM71682.1 - 0.006 16.3 2.3 3.9 7.3 0.6 4.1 2 2 1 3 3 3 2 Leucine rich repeat F-box-like PF12937.7 KFM71683.1 - 3.3e-14 52.5 0.9 4e-14 52.2 0.9 1.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM71683.1 - 1.6e-12 46.9 2.1 2e-12 46.7 2.1 1.1 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFM71683.1 - 0.056 13.3 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 F-box Cyto_heme_lyase PF01265.17 KFM71685.1 - 2.4e-67 227.6 9.4 1.3e-66 225.2 9.4 1.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase HTH_Tnp_Tc3_2 PF01498.18 KFM71686.1 - 2e-16 60.0 2.2 4.4e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71686.1 - 9.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71687.1 - 1.9e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71687.1 - 7.7e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Trypsin PF00089.26 KFM71689.1 - 9.3e-09 35.4 0.0 9.9e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 Trypsin HRG PF16954.5 KFM71690.1 - 0.00031 21.1 1.7 0.00031 21.1 1.7 2.9 2 1 0 2 2 2 1 Haem-transporter, endosomal/lysosomal, haem-responsive gene Voltage_CLC PF00654.20 KFM71692.1 - 1.3e-05 24.6 0.3 1.4e-05 24.6 0.3 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel Ndc1_Nup PF09531.10 KFM71692.1 - 0.064 11.9 2.0 0.064 11.9 2.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Voltage_CLC PF00654.20 KFM71693.1 - 0.012 14.9 0.1 0.013 14.8 0.1 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel Voltage_CLC PF00654.20 KFM71694.1 - 2.9e-19 69.6 1.7 3.2e-19 69.4 1.7 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel zf-H2C2_2 PF13465.6 KFM71698.1 - 8.2e-19 67.1 15.5 2.7e-07 30.7 1.0 3.4 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71698.1 - 2.9e-08 33.7 17.5 0.00043 20.6 1.2 4.1 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71698.1 - 1.3e-06 28.7 17.0 0.0017 19.1 1.3 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM71698.1 - 1.8e-05 24.6 15.3 0.027 14.5 0.5 3.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM71698.1 - 0.0013 19.0 7.5 4.3 7.7 0.3 3.7 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM71698.1 - 0.0093 15.8 8.3 0.53 10.3 0.2 3.3 3 0 0 3 3 3 2 zinc-finger of a C2HC-type VATC PF18716.1 KFM71698.1 - 0.011 15.5 4.8 6.6 6.7 0.1 3.3 3 0 0 3 3 3 0 Vms1-associating treble clef domain zf-met PF12874.7 KFM71698.1 - 0.013 15.8 12.5 4 8.0 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FYVE PF01363.21 KFM71698.1 - 0.02 15.0 6.2 0.074 13.2 6.2 2.0 1 1 0 1 1 1 0 FYVE zinc finger C1_1 PF00130.22 KFM71698.1 - 0.021 14.7 8.6 0.033 14.1 2.4 2.9 2 1 1 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Sec23_Sec24 PF04810.15 KFM71698.1 - 0.05 13.7 2.0 12 6.1 0.1 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 KFM71698.1 - 0.14 11.6 1.5 0.24 10.8 0.4 1.9 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_11 PF16622.5 KFM71698.1 - 0.18 11.6 7.8 0.3 10.9 0.7 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KFM71698.1 - 1.2 8.8 6.8 16 5.2 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger C5HCH PF17982.1 KFM71698.1 - 1.7 8.9 9.0 28 5.0 0.2 3.9 4 0 0 4 4 4 0 NSD Cys-His rich domain zf-H2C2_5 PF13909.6 KFM71698.1 - 2.8 7.8 7.2 8.9 6.2 2.6 3.5 3 1 0 3 3 3 0 C2H2-type zinc-finger domain RecR PF02132.15 KFM71698.1 - 3 7.5 7.4 2.7 7.6 0.2 2.9 3 0 0 3 3 3 0 RecR protein zf-H2C2_2 PF13465.6 KFM71699.1 - 3.7e-39 131.4 29.8 4.6e-11 42.6 1.3 5.1 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71699.1 - 8.2e-30 101.6 37.2 5.6e-07 29.7 2.4 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71699.1 - 9.6e-22 75.8 34.0 3.1e-05 24.4 1.6 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KFM71699.1 - 1.7e-17 63.1 34.2 4.2e-05 23.8 2.0 5.5 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM71699.1 - 1.4e-14 53.6 30.0 7.3e-05 22.7 1.6 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM71699.1 - 6.1e-12 45.5 30.6 0.0049 17.1 0.1 5.3 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM71699.1 - 5.3e-09 36.2 3.5 0.074 13.3 1.5 4.5 1 1 3 4 4 4 3 BolA-like protein Baculo_IE-1 PF05290.11 KFM71699.1 - 3.5e-08 33.5 16.2 0.027 14.4 0.4 4.8 1 1 4 5 5 5 3 Baculovirus immediate-early protein (IE-0) zf-H2C2_5 PF13909.6 KFM71699.1 - 1.2e-07 31.3 40.6 0.007 16.1 2.2 5.3 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM71699.1 - 5.7e-06 26.1 20.0 1.5 8.9 1.3 5.7 5 2 0 5 5 5 2 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM71699.1 - 9.7e-05 22.3 13.8 3 8.0 0.1 5.0 4 1 1 5 5 5 2 Sec23/Sec24 zinc finger zf_UBZ PF18439.1 KFM71699.1 - 0.00036 20.1 20.7 0.33 10.6 0.2 5.2 5 0 0 5 5 5 1 Ubiquitin-Binding Zinc Finger zf-FCS PF06467.14 KFM71699.1 - 0.00041 20.2 21.2 1.7 8.6 0.3 5.1 4 1 1 5 5 5 2 MYM-type Zinc finger with FCS sequence motif C1_1 PF00130.22 KFM71699.1 - 0.00079 19.3 22.8 0.18 11.7 3.1 4.6 2 2 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KFM71699.1 - 0.00087 19.4 19.8 0.66 10.1 0.7 5.0 1 1 4 5 5 5 1 KIAA1045 RING finger YyzF PF14116.6 KFM71699.1 - 0.0022 18.0 17.6 1.5 8.9 0.3 5.1 5 0 0 5 5 5 1 YyzF-like protein zf-C2H2_2 PF12756.7 KFM71699.1 - 0.0026 18.1 29.3 0.15 12.4 2.0 4.7 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) ZZ PF00569.17 KFM71699.1 - 0.0037 17.0 20.3 1.6 8.6 0.1 5.2 5 0 0 5 5 5 2 Zinc finger, ZZ type zinc-ribbons_6 PF07191.12 KFM71699.1 - 0.0047 16.9 20.7 6.3 6.9 3.0 4.7 1 1 3 4 4 4 0 zinc-ribbons zf-C2H2_11 PF16622.5 KFM71699.1 - 0.0048 16.6 21.6 0.33 10.7 0.6 4.7 5 0 0 5 5 5 3 zinc-finger C2H2-type VATC PF18716.1 KFM71699.1 - 0.012 15.4 13.9 12 5.9 0.2 5.1 5 0 0 5 5 5 0 Vms1-associating treble clef domain Zn-ribbon_8 PF09723.10 KFM71699.1 - 0.018 15.2 19.2 0.77 9.9 3.5 4.4 2 1 1 4 4 4 0 Zinc ribbon domain FYVE PF01363.21 KFM71699.1 - 0.045 13.9 25.0 5.7 7.2 9.7 3.9 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_3rep PF18868.1 KFM71699.1 - 0.08 13.6 13.1 1.8 9.2 7.2 3.5 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF3290 PF11694.8 KFM71699.1 - 0.086 12.8 0.4 17 5.4 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3290) zf-AN1 PF01428.16 KFM71699.1 - 0.092 12.9 26.3 2.5 8.3 1.3 5.2 2 1 3 5 5 5 0 AN1-like Zinc finger zf-BED PF02892.15 KFM71699.1 - 0.093 12.8 32.6 0.14 12.2 5.6 5.0 1 1 4 5 5 5 0 BED zinc finger C1_4 PF07975.12 KFM71699.1 - 0.098 12.9 22.9 2 8.7 4.6 3.9 1 1 3 4 4 4 0 TFIIH C1-like domain Sprouty PF05210.13 KFM71699.1 - 0.13 12.6 18.4 1.1 9.7 6.7 2.1 1 1 1 2 2 2 0 Sprouty protein (Spry) XPA_N PF01286.18 KFM71699.1 - 0.16 12.0 16.9 16 5.7 0.2 5.1 5 0 0 5 5 5 0 XPA protein N-terminal YceD PF02620.17 KFM71699.1 - 0.24 11.5 4.7 5 7.3 0.0 3.5 1 1 3 4 4 4 0 Large ribosomal RNA subunit accumulation protein YceD ADK_lid PF05191.14 KFM71699.1 - 0.31 11.0 13.3 0.17 11.9 1.8 3.8 4 0 0 4 4 4 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM71699.1 - 0.33 11.7 21.1 0.57 11.0 2.8 3.0 1 1 2 3 3 3 0 zinc-ribbon family C1_2 PF03107.16 KFM71699.1 - 0.66 10.3 30.9 57 4.2 7.2 4.9 1 1 2 3 3 3 0 C1 domain zf-C2H2_9 PF16293.5 KFM71699.1 - 0.73 9.7 16.4 5.9 6.8 0.2 4.4 1 1 4 5 5 5 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM71699.1 - 0.78 9.6 12.0 7.2 6.5 0.2 4.4 1 1 4 5 5 5 0 GAGA factor HNH_5 PF14279.6 KFM71699.1 - 0.85 9.5 19.9 5.7 6.9 3.9 4.9 3 2 0 3 3 3 0 HNH endonuclease TRAF6_Z2 PF18048.1 KFM71699.1 - 1.4 9.1 15.7 11 6.2 2.3 4.5 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-HIT PF04438.16 KFM71699.1 - 1.5 8.7 25.9 7.8 6.5 1.8 5.2 5 0 0 5 5 5 0 HIT zinc finger PHF5 PF03660.14 KFM71699.1 - 1.8 8.8 14.5 7.8 6.8 6.7 2.6 1 1 2 3 3 3 0 PHF5-like protein Zn-C2H2_12 PF18112.1 KFM71699.1 - 2.4 8.7 24.6 5.5 7.6 3.0 5.1 5 0 0 5 5 4 0 Autophagy receptor zinc finger-C2H2 domain C5HCH PF17982.1 KFM71699.1 - 4.1 7.6 22.3 7.1 6.9 1.6 4.9 2 1 2 5 5 5 0 NSD Cys-His rich domain zf-MYST PF17772.1 KFM71699.1 - 4.2 7.1 22.7 5.1 6.8 0.1 4.6 1 1 4 5 5 5 0 MYST family zinc finger domain UBZ_FAAP20 PF15750.5 KFM71699.1 - 6.8 6.7 13.0 71 3.5 0.0 4.9 5 0 0 5 5 5 0 Ubiquitin-binding zinc-finger DUF3449 PF11931.8 KFM71699.1 - 8.7 6.1 23.1 8.4 6.1 2.6 4.8 1 1 4 5 5 5 0 Domain of unknown function (DUF3449) HTH_Tnp_Tc3_2 PF01498.18 KFM71700.1 - 1.6e-09 37.9 1.6 2.7e-09 37.1 1.6 1.4 1 0 0 1 1 1 1 Transposase HTH_12 PF08461.10 KFM71700.1 - 0.0076 16.2 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain DDE_3 PF13358.6 KFM71702.1 - 0.0025 17.6 0.1 0.0035 17.1 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Cofilin_ADF PF00241.20 KFM71703.1 - 9.6e-26 90.0 1.7 1.1e-25 89.7 1.7 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2004 PF09406.10 KFM71703.1 - 0.043 14.2 0.4 0.11 12.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) PAH PF02671.21 KFM71703.1 - 0.48 10.6 4.6 0.33 11.1 0.9 2.4 2 1 0 2 2 2 0 Paired amphipathic helix repeat BBS2_Mid PF14783.6 KFM71705.1 - 0.0031 17.5 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KFM71705.1 - 0.044 13.1 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain PH_10 PF15411.6 KFM71706.1 - 0.15 12.4 0.1 0.19 12.0 0.1 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 KFM71706.1 - 0.16 12.5 0.1 0.2 12.2 0.1 1.2 1 0 0 1 1 1 0 PH domain Lzipper-MIP1 PF14389.6 KFM71707.1 - 0.0027 18.0 0.1 0.0029 17.9 0.1 1.2 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 RhoGEF PF00621.20 KFM71708.1 - 2.3e-17 63.8 0.8 2.3e-17 63.8 0.8 1.4 2 0 0 2 2 2 1 RhoGEF domain GSDH PF07995.11 KFM71708.1 - 0.098 11.9 0.2 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase RhoGEF PF00621.20 KFM71709.1 - 1.5e-12 48.1 0.2 1.8e-12 47.9 0.2 1.1 1 0 0 1 1 1 1 RhoGEF domain HLH PF00010.26 KFM71712.1 - 2.8e-11 43.2 1.9 4.8e-11 42.4 1.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM71714.1 - 5.2e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71714.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71714.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71714.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Cytochrom_B561 PF03188.16 KFM71715.1 - 1.1e-44 151.9 11.1 1.1e-44 151.9 11.1 2.2 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Ferric_reduct PF01794.19 KFM71715.1 - 0.0072 16.5 3.8 0.0072 16.5 3.8 2.8 1 1 2 3 3 3 2 Ferric reductase like transmembrane component DUF1980 PF09323.10 KFM71715.1 - 0.63 9.9 3.6 1.2 9.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4231 PF14015.6 KFM71715.1 - 0.72 10.4 4.3 1.6 9.2 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF4079 PF13301.6 KFM71715.1 - 1.2 9.2 11.9 2.2 8.4 10.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 KFM71715.1 - 3.8 7.1 18.8 39 3.8 18.8 2.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2254 PF10011.9 KFM71715.1 - 6.7 5.4 6.7 1.6 7.5 0.6 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) Homeodomain PF00046.29 KFM71716.1 - 1.1e-06 28.4 0.1 1.2e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Homeodomain PspC PF04024.12 KFM71716.1 - 0.088 12.6 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 PspC domain ABC2_membrane_3 PF12698.7 KFM71718.1 - 0.16 11.0 3.8 0.18 10.9 3.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Clathrin PF00637.20 KFM71721.1 - 2.5e-25 89.0 8.7 5.1e-25 88.0 1.7 3.4 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.9 KFM71721.1 - 0.00029 21.1 1.5 0.028 14.7 0.1 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KFM71721.1 - 0.00068 20.1 0.4 0.00068 20.1 0.4 2.0 2 0 0 2 2 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 KFM71721.1 - 0.0066 16.2 0.8 0.0066 16.2 0.8 2.3 2 0 0 2 2 2 1 RING-like zinc finger ANAPC4_WD40 PF12894.7 KFM71721.1 - 0.011 16.1 0.6 3.7 7.9 0.0 3.4 2 2 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM71721.1 - 0.019 15.8 0.3 1.4 9.9 0.1 3.3 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-RING_5 PF14634.6 KFM71721.1 - 0.027 14.4 9.0 0.077 13.0 9.0 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM71721.1 - 0.18 11.7 12.2 0.9 9.5 4.4 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFM71721.1 - 0.48 10.8 11.5 0.9 9.9 10.0 2.2 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 KFM71721.1 - 2.4 8.1 7.2 2.2 8.2 3.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KFM71721.1 - 3 8.0 6.4 1 9.5 1.7 2.4 2 0 0 2 2 2 0 Zinc-finger HTH_Tnp_Tc5 PF03221.16 KFM71722.1 - 2.9e-17 62.4 0.1 5.4e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM71722.1 - 3.1e-07 29.9 0.1 6.2e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFM71722.1 - 1.9e-05 24.3 0.0 0.00017 21.3 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71722.1 - 0.00048 20.2 0.0 0.01 15.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM71722.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 zf-H2C2_2 PF13465.6 KFM71723.1 - 1.7e-154 496.0 146.4 8.6e-10 38.6 0.7 19.3 19 0 0 19 19 19 19 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71723.1 - 1e-99 321.8 178.3 8.5e-07 29.1 0.8 19.1 19 0 0 19 19 19 19 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71723.1 - 4.6e-70 226.1 159.2 0.00019 22.0 1.0 19.1 19 0 0 19 19 19 19 C2H2-type zinc finger zf-met PF12874.7 KFM71723.1 - 1.4e-59 196.9 151.1 0.00016 21.9 2.5 19.2 19 0 0 19 19 19 18 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM71723.1 - 1.3e-35 120.9 111.4 0.0065 16.7 0.3 18.7 19 0 0 19 19 18 17 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM71723.1 - 1.7e-34 117.1 127.2 0.011 15.7 3.0 19.0 19 0 0 19 19 19 17 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM71723.1 - 1.3e-27 95.5 71.1 0.0047 16.9 0.1 18.2 13 4 5 18 18 18 10 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.6 KFM71723.1 - 3.1e-26 90.8 104.6 0.0013 18.5 0.1 18.9 19 0 0 19 19 19 12 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM71723.1 - 1e-19 70.0 111.4 0.083 12.7 0.2 18.8 19 0 0 19 19 19 9 zinc-finger C2H2-type BolA PF01722.18 KFM71723.1 - 3.2e-17 62.6 33.2 1.2 9.5 0.0 13.3 1 1 11 13 13 13 7 BolA-like protein GAGA PF09237.11 KFM71723.1 - 2.1e-09 37.0 30.8 0.59 10.0 0.1 12.4 3 3 10 14 14 14 3 GAGA factor Yop-YscD_ppl PF16693.5 KFM71723.1 - 2.3e-08 33.8 0.0 1.1 8.7 0.0 5.1 3 1 3 6 6 6 3 Inner membrane component of T3SS, periplasmic domain zf-C2HC_2 PF13913.6 KFM71723.1 - 2.5e-08 33.6 87.8 0.25 11.3 0.1 18.1 18 0 0 18 18 18 4 zinc-finger of a C2HC-type C1_4 PF07975.12 KFM71723.1 - 2.1e-06 27.8 93.5 0.044 14.0 6.0 11.3 3 2 9 14 14 14 6 TFIIH C1-like domain Baculo_IE-1 PF05290.11 KFM71723.1 - 2.4e-05 24.3 68.1 0.74 9.8 3.3 14.2 1 1 9 10 10 10 3 Baculovirus immediate-early protein (IE-0) zinc_ribbon_15 PF17032.5 KFM71723.1 - 4.1e-05 24.2 87.3 0.86 10.4 2.2 9.6 2 2 9 12 12 12 6 zinc-ribbon family VirE1 PF12189.8 KFM71723.1 - 9.6e-05 22.4 14.8 6.2 7.0 0.1 9.5 7 4 3 10 10 10 1 Single-strand DNA-binding protein Zf_RING PF16744.5 KFM71723.1 - 0.00016 21.7 96.0 2.9 8.1 0.8 18.0 1 1 16 17 17 17 1 KIAA1045 RING finger Tox-HNH-HHH PF15637.6 KFM71723.1 - 0.00043 20.4 11.2 4 7.7 0.0 6.5 1 1 6 8 8 8 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif CIA30 PF08547.12 KFM71723.1 - 0.0012 18.9 0.0 42 4.1 0.0 5.1 1 1 4 6 6 6 0 Complex I intermediate-associated protein 30 (CIA30) Zn_ribbon_SprT PF17283.2 KFM71723.1 - 0.0078 16.1 73.3 1.7 8.6 1.2 15.9 11 5 5 16 16 16 1 SprT-like zinc ribbon domain DUF2256 PF10013.9 KFM71723.1 - 0.016 15.3 74.0 41 4.4 0.1 17.7 18 0 0 18 18 18 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM71723.1 - 0.028 14.5 101.0 8.6 6.6 0.5 16.9 17 2 0 17 17 17 0 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM71723.1 - 0.3 11.2 93.4 0.45 10.6 6.4 8.0 1 1 9 10 10 10 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-C2H2_12 PF18112.1 KFM71723.1 - 0.82 10.2 94.7 3.9 8.0 0.5 18.0 18 0 0 18 18 18 0 Autophagy receptor zinc finger-C2H2 domain Complex1_49kDa PF00346.19 KFM71723.1 - 1.7 7.7 18.2 3.9 6.5 0.2 4.6 1 1 3 5 5 5 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Zn-ribbon_8 PF09723.10 KFM71723.1 - 5.4 7.2 75.8 9.7 6.4 1.5 11.3 1 1 14 16 16 16 0 Zinc ribbon domain Retrotran_gag_2 PF14223.6 KFM71724.1 - 2e-19 69.6 0.0 2.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KFM71724.1 - 0.00015 21.4 1.3 0.00029 20.4 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-H2C2_2 PF13465.6 KFM71725.1 - 1.4e-28 97.9 23.3 5.4e-09 36.1 0.9 4.1 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71725.1 - 4.2e-17 61.6 27.8 2.1e-06 27.8 1.9 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71725.1 - 1.3e-12 47.4 23.8 0.00032 21.3 0.5 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 KFM71725.1 - 4.3e-12 46.0 26.1 4.8e-06 26.8 1.0 4.7 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM71725.1 - 2.4e-08 34.0 18.5 0.0025 18.1 0.0 4.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM71725.1 - 8.2e-07 29.0 1.4 0.29 11.2 0.0 3.3 2 1 1 3 3 3 2 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 KFM71725.1 - 2.5e-06 27.1 14.7 0.058 13.2 0.3 4.2 4 0 0 4 4 4 2 zinc-finger C2H2-type Zf_RING PF16744.5 KFM71725.1 - 0.00018 21.5 8.5 0.27 11.4 0.1 3.6 1 1 2 3 3 3 2 KIAA1045 RING finger zf-C2H2_9 PF16293.5 KFM71725.1 - 0.0013 18.5 8.6 0.65 9.9 0.2 3.5 2 1 2 4 4 4 2 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM71725.1 - 0.0034 17.4 7.7 0.46 10.6 0.4 3.3 3 0 0 3 3 3 2 DBF zinc finger Baculo_IE-1 PF05290.11 KFM71725.1 - 0.0044 17.0 3.4 1.5 8.7 0.1 3.1 1 1 2 3 3 3 1 Baculovirus immediate-early protein (IE-0) zf-Di19 PF05605.12 KFM71725.1 - 0.0053 17.0 11.1 0.035 14.4 2.7 2.9 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFM71725.1 - 0.0077 16.2 19.3 0.015 15.3 0.2 4.4 5 0 0 5 5 4 2 C2H2-type zinc finger A_deaminase PF00962.22 KFM71725.1 - 0.012 15.0 0.5 1.3 8.3 0.0 2.5 1 1 2 3 3 3 0 Adenosine/AMP deaminase zf-Dof PF02701.15 KFM71725.1 - 0.017 15.2 5.3 4.2 7.6 0.0 3.3 1 1 1 2 2 2 0 Dof domain, zinc finger zinc-ribbons_6 PF07191.12 KFM71725.1 - 0.022 14.8 8.7 4.1 7.5 4.8 3.1 1 1 2 3 3 3 0 zinc-ribbons C1_4 PF07975.12 KFM71725.1 - 0.023 15.0 9.3 1.2 9.4 3.8 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain zf_UBZ PF18439.1 KFM71725.1 - 0.026 14.1 4.9 17 5.1 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM71725.1 - 0.026 14.4 9.6 0.82 9.6 0.2 4.6 4 1 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KFM71725.1 - 0.048 14.1 1.5 0.048 14.1 1.5 3.4 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 KFM71725.1 - 0.11 13.2 6.3 0.64 10.7 0.9 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats HNH PF01844.23 KFM71725.1 - 0.16 12.2 9.0 10 6.4 0.3 3.4 3 0 0 3 3 3 0 HNH endonuclease Zn-ribbon_8 PF09723.10 KFM71725.1 - 0.16 12.1 9.3 2.8 8.1 1.5 3.1 2 2 1 3 3 3 0 Zinc ribbon domain HypA PF01155.19 KFM71725.1 - 0.18 11.9 5.0 0.28 11.2 2.5 2.2 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_2 PF03107.16 KFM71725.1 - 0.23 11.8 13.5 30 5.0 9.2 3.5 2 1 0 2 2 2 0 C1 domain zf-MYST PF17772.1 KFM71725.1 - 0.26 10.9 12.1 3.9 7.2 0.5 3.4 2 1 2 4 4 3 0 MYST family zinc finger domain FYVE PF01363.21 KFM71725.1 - 0.38 10.9 13.0 1.9 8.7 9.1 2.8 1 1 1 2 2 2 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM71725.1 - 0.47 11.2 9.8 1.3 9.9 1.3 2.2 1 1 1 2 2 2 0 zinc-ribbon family zf-CCHC_2 PF13696.6 KFM71725.1 - 0.48 10.3 16.8 2.5 8.0 0.4 3.5 4 0 0 4 4 3 0 Zinc knuckle DUF2197 PF09963.9 KFM71725.1 - 0.54 10.5 13.0 7.6 6.9 0.4 3.5 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-AN1 PF01428.16 KFM71725.1 - 0.69 10.1 9.5 27 5.0 0.1 3.9 4 0 0 4 4 4 0 AN1-like Zinc finger UBZ_FAAP20 PF15750.5 KFM71725.1 - 1.1 9.3 5.1 11 6.0 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-BED PF02892.15 KFM71725.1 - 1.1 9.3 17.4 1.5 8.9 0.7 3.7 1 1 2 3 3 3 0 BED zinc finger zf_C2H2_ZHX PF18387.1 KFM71725.1 - 1.7 8.3 10.9 0.96 9.1 1.2 3.0 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFM71725.1 - 2.6 8.5 19.0 33 4.9 7.1 3.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.6 KFM71725.1 - 2.9 7.8 9.2 30 4.6 0.1 3.4 3 1 0 3 3 3 0 Probable zinc-ribbon domain Vps39_2 PF10367.9 KFM71725.1 - 5.2 7.5 14.6 13 6.3 0.2 3.6 1 1 3 4 4 4 0 Vacuolar sorting protein 39 domain 2 Zn-C2H2_12 PF18112.1 KFM71725.1 - 5.6 7.5 13.2 11 6.6 0.1 4.3 5 0 0 5 5 4 0 Autophagy receptor zinc finger-C2H2 domain DUF629 PF04780.12 KFM71725.1 - 9.2 4.7 14.5 2.9 6.3 2.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.6 KFM71726.1 - 1.1e-49 164.7 45.6 8.9e-10 38.6 1.1 6.5 7 0 0 7 7 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71726.1 - 9.2e-33 110.9 52.5 1.4e-05 25.2 2.1 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71726.1 - 1.8e-23 81.2 46.9 0.001 19.7 1.6 7.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 KFM71726.1 - 1.1e-17 63.8 43.2 0.0013 19.1 0.4 7.1 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM71726.1 - 8.8e-13 48.2 32.1 0.019 15.3 0.4 7.2 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM71726.1 - 4.4e-12 45.9 12.6 0.029 14.4 0.0 6.0 4 2 2 6 6 6 3 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 KFM71726.1 - 1.6e-07 31.2 49.6 0.061 13.3 0.2 7.8 8 0 0 8 8 7 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM71726.1 - 3.8e-07 29.8 30.1 0.019 14.7 0.2 6.7 7 0 0 7 7 7 3 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM71726.1 - 1.3e-05 24.9 34.3 0.074 12.8 0.5 6.6 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-DBF PF07535.12 KFM71726.1 - 1.4e-05 25.0 27.4 1.8 8.7 0.3 6.5 5 1 1 6 6 6 2 DBF zinc finger BolA PF01722.18 KFM71726.1 - 4.5e-05 23.6 6.2 0.23 11.8 1.1 4.5 1 1 3 4 4 4 1 BolA-like protein GAGA PF09237.11 KFM71726.1 - 0.00014 21.6 6.2 5.3 6.9 0.0 5.1 1 1 5 6 6 6 0 GAGA factor zf-C2HC_2 PF13913.6 KFM71726.1 - 0.00022 21.0 20.9 3.5 7.6 0.1 7.2 7 0 0 7 7 7 1 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFM71726.1 - 0.00023 21.2 24.7 3.4 7.8 0.2 6.0 1 1 4 5 5 5 1 KIAA1045 RING finger zinc_ribbon_15 PF17032.5 KFM71726.1 - 0.00091 19.9 24.0 0.41 11.4 3.1 4.0 1 1 3 4 4 4 2 zinc-ribbon family A_deaminase PF00962.22 KFM71726.1 - 0.00096 18.6 7.5 0.8 9.0 0.8 3.1 1 1 2 3 3 3 3 Adenosine/AMP deaminase zf-C2H2_9 PF16293.5 KFM71726.1 - 0.0012 18.6 23.8 0.2 11.6 0.2 6.1 3 1 4 7 7 7 1 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM71726.1 - 0.0018 18.4 24.7 0.0041 17.2 8.3 3.2 1 1 2 3 3 3 2 Putative ribonucleoprotein zinc-finger pf C4 type Amidohydro_1 PF01979.20 KFM71726.1 - 0.0027 17.1 6.5 2.9 7.1 0.2 3.9 1 1 3 4 4 4 1 Amidohydrolase family DUF2256 PF10013.9 KFM71726.1 - 0.0043 17.1 22.7 8.9 6.5 0.0 6.4 7 0 0 7 7 6 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4825 PF16107.5 KFM71726.1 - 0.0064 16.6 0.0 14 5.9 0.0 4.0 1 1 3 5 5 5 0 Domain of unknown function (DUF4825) Yop-YscD_ppl PF16693.5 KFM71726.1 - 0.0072 15.8 0.0 1.6 8.1 0.0 2.1 1 1 0 2 2 2 1 Inner membrane component of T3SS, periplasmic domain zinc-ribbons_6 PF07191.12 KFM71726.1 - 0.012 15.5 23.0 1.2 9.2 2.0 5.2 1 1 2 3 3 3 0 zinc-ribbons zf-C2H2_8 PF15909.5 KFM71726.1 - 0.015 15.5 24.8 0.42 11.0 6.0 3.9 1 1 1 3 3 3 0 C2H2-type zinc ribbon zf-RING_UBOX PF13445.6 KFM71726.1 - 0.037 14.1 6.3 89 3.2 0.0 5.5 6 0 0 6 6 6 0 RING-type zinc-finger YyzF PF14116.6 KFM71726.1 - 0.072 13.1 17.0 20 5.3 0.1 5.9 6 0 0 6 6 6 0 YyzF-like protein zf-MYST PF17772.1 KFM71726.1 - 0.1 12.3 28.2 1.6 8.4 0.4 5.9 1 1 5 6 6 6 0 MYST family zinc finger domain Zn-C2H2_12 PF18112.1 KFM71726.1 - 0.14 12.6 26.5 8.5 6.9 0.5 7.3 7 0 0 7 7 7 0 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 KFM71726.1 - 0.28 11.3 23.9 1.6 8.9 2.3 4.6 2 2 3 5 5 5 0 Zinc ribbon domain Vps39_2 PF10367.9 KFM71726.1 - 0.32 11.5 32.6 5.5 7.5 1.1 6.1 1 1 5 6 6 6 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_2 PF12756.7 KFM71726.1 - 0.39 11.1 41.3 1.1 9.6 2.3 6.2 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Z1 PF10593.9 KFM71726.1 - 0.54 9.7 3.0 0.21 11.0 0.3 1.7 2 0 0 2 2 2 0 Z1 domain C1_4 PF07975.12 KFM71726.1 - 0.58 10.4 29.0 1.9 8.8 2.6 4.9 1 1 5 6 6 6 0 TFIIH C1-like domain HNH PF01844.23 KFM71726.1 - 0.82 9.9 29.7 7 6.9 0.2 6.6 7 0 0 7 7 7 0 HNH endonuclease Trm112p PF03966.16 KFM71726.1 - 1.3 9.7 5.9 6.5 7.4 0.1 3.1 2 1 0 2 2 2 0 Trm112p-like protein LIM PF00412.22 KFM71726.1 - 1.4 9.2 27.4 30 4.9 3.4 5.8 1 1 5 6 6 6 0 LIM domain DUF3268 PF11672.8 KFM71726.1 - 1.4 9.3 14.4 11 6.4 2.9 3.3 1 1 3 4 4 4 0 zinc-finger-containing domain zf-Paramyx-P PF13008.7 KFM71726.1 - 1.7 8.2 14.8 45 3.6 0.0 5.4 6 0 0 6 6 6 0 Zinc-binding domain of Paramyxoviridae V protein zf_C2H2_ZHX PF18387.1 KFM71726.1 - 1.9 8.2 25.8 2.1 8.0 1.0 4.4 2 2 3 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-HIT PF04438.16 KFM71726.1 - 3.4 7.6 25.7 19 5.2 0.3 6.2 6 0 0 6 6 6 0 HIT zinc finger A2L_zn_ribbon PF08792.10 KFM71726.1 - 3.6 7.4 27.0 11 5.9 0.2 6.1 6 0 0 6 6 6 0 A2L zinc ribbon domain zf_UBZ PF18439.1 KFM71726.1 - 4 7.1 25.6 21 4.8 0.4 6.9 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 KFM71726.1 - 5.5 7.0 23.3 20 5.2 0.2 6.0 6 0 0 6 6 6 0 Probable zinc-ribbon domain DUF2197 PF09963.9 KFM71726.1 - 5.8 7.2 29.7 4 7.8 5.3 5.7 1 1 5 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-AN1 PF01428.16 KFM71726.1 - 5.9 7.2 22.8 24 5.2 0.1 6.3 7 0 0 7 7 6 0 AN1-like Zinc finger zf-H2C2_2 PF13465.6 KFM71727.1 - 1.1e-60 199.4 63.5 4.4e-09 36.4 0.5 8.6 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71727.1 - 2.5e-38 128.4 67.6 7.9e-06 26.1 2.5 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71727.1 - 1.3e-24 84.7 61.6 0.0012 19.6 1.0 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.7 KFM71727.1 - 4.3e-21 74.6 63.1 3.8e-05 23.9 2.2 8.3 8 0 0 8 8 8 7 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.15 KFM71727.1 - 2.4e-10 40.3 21.1 0.24 11.5 0.1 7.1 3 2 4 7 7 7 3 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.6 KFM71727.1 - 1.7e-08 34.0 56.1 0.06 13.1 0.8 8.4 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM71727.1 - 6e-08 32.8 46.3 0.19 12.0 0.6 7.9 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM71727.1 - 2.2e-05 24.2 7.9 3 7.7 0.0 5.6 2 2 4 6 6 6 2 GAGA factor zf-C2H2_6 PF13912.6 KFM71727.1 - 2.6e-05 24.1 60.0 0.026 14.5 0.5 8.9 8 2 0 8 8 8 5 C2H2-type zinc finger DUF4825 PF16107.5 KFM71727.1 - 0.00015 21.9 0.2 3.3 7.9 0.0 4.6 1 1 4 5 5 5 1 Domain of unknown function (DUF4825) zf-DBF PF07535.12 KFM71727.1 - 0.00024 21.1 28.5 3.5 7.8 0.4 6.8 7 0 0 7 7 6 3 DBF zinc finger zf-C2H2_11 PF16622.5 KFM71727.1 - 0.00031 20.4 43.4 0.039 13.7 0.2 7.8 8 0 0 8 8 8 3 zinc-finger C2H2-type Yop-YscD_ppl PF16693.5 KFM71727.1 - 0.0022 17.5 0.0 0.8 9.1 0.0 2.3 1 1 0 2 2 2 1 Inner membrane component of T3SS, periplasmic domain Tox-HNH-HHH PF15637.6 KFM71727.1 - 0.0041 17.3 0.2 4.2 7.6 0.0 3.3 1 1 1 3 3 3 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_9 PF16293.5 KFM71727.1 - 0.0086 15.9 34.7 0.25 11.2 0.1 7.6 2 1 6 8 8 8 2 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM71727.1 - 0.0095 15.8 26.1 2.1 8.3 0.2 6.8 7 0 0 7 7 7 2 zinc-finger of a C2HC-type A_deaminase PF00962.22 KFM71727.1 - 0.017 14.5 10.3 0.23 10.7 0.4 3.6 1 1 1 3 3 3 0 Adenosine/AMP deaminase C1_1 PF00130.22 KFM71727.1 - 0.021 14.7 39.9 0.89 9.5 6.3 5.7 1 1 4 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KFM71727.1 - 0.024 14.8 36.1 3.1 8.0 0.2 7.0 1 1 6 7 7 7 0 KIAA1045 RING finger C1_4 PF07975.12 KFM71727.1 - 0.031 14.5 36.7 2 8.7 3.1 5.6 1 1 4 6 6 6 0 TFIIH C1-like domain NusB PF01029.18 KFM71727.1 - 0.04 14.1 0.3 11 6.3 0.0 3.4 2 2 3 5 5 5 0 NusB family DZR PF12773.7 KFM71727.1 - 0.043 13.8 32.1 14 5.8 0.2 4.5 1 1 2 3 3 3 0 Double zinc ribbon ProQ PF04352.13 KFM71727.1 - 0.057 13.3 0.3 25 4.8 0.0 3.6 2 2 1 4 4 4 0 ProQ/FINO family zf-RRPl_C4 PF17026.5 KFM71727.1 - 0.096 12.8 35.8 5.1 7.2 9.8 4.0 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Complex1_49kDa PF00346.19 KFM71727.1 - 0.1 11.6 1.0 2.1 7.3 0.1 2.2 1 1 1 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zinc_ribbon_15 PF17032.5 KFM71727.1 - 0.39 11.5 34.8 1.7 9.5 1.7 4.2 1 1 1 4 4 4 0 zinc-ribbon family DUF2039 PF10217.9 KFM71727.1 - 3.5 8.0 36.2 6.3 7.2 11.3 3.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2039) DUF5330 PF17264.2 KFM71727.1 - 3.6 7.7 20.8 14 5.7 0.1 6.1 7 0 0 7 7 7 0 Family of unknown function (DUF5330) zf-H2C2_2 PF13465.6 KFM71728.1 - 1e-77 253.3 67.6 1.2e-09 38.1 0.6 10.8 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71728.1 - 1.1e-55 183.0 75.2 3.3e-06 27.2 0.5 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71728.1 - 3.9e-38 126.8 68.8 0.00028 21.5 0.9 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM71728.1 - 1.2e-36 124.0 70.6 0.00012 22.4 0.5 10.2 10 0 0 10 10 10 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM71728.1 - 9.9e-20 70.3 50.5 0.01 16.1 0.1 10.2 10 0 0 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM71728.1 - 3e-16 59.2 25.9 0.12 12.4 0.3 9.1 5 3 4 9 9 9 6 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.6 KFM71728.1 - 2.7e-15 55.8 57.5 0.098 12.4 0.5 10.4 10 0 0 10 10 10 8 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM71728.1 - 1.6e-14 53.3 49.3 0.0084 15.9 0.2 10.0 10 0 0 10 10 10 5 zinc-finger C2H2-type BolA PF01722.18 KFM71728.1 - 1.7e-10 41.0 11.6 0.35 11.2 0.2 6.9 1 1 6 7 7 7 4 BolA-like protein zf-C2HC_2 PF13913.6 KFM71728.1 - 1e-07 31.7 37.5 0.64 10.0 0.4 9.9 11 0 0 11 11 10 3 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM71728.1 - 2.5e-07 30.4 40.9 1.2 9.1 0.1 9.9 2 2 8 10 10 10 3 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 KFM71728.1 - 3.6e-07 30.0 82.1 0.0091 16.0 0.2 11.8 12 1 0 12 12 12 6 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFM71728.1 - 3.6e-06 27.6 37.2 0.025 15.3 2.1 5.2 2 1 2 5 5 5 5 zinc-ribbon family Baculo_IE-1 PF05290.11 KFM71728.1 - 6.9e-06 26.1 29.9 0.26 11.2 0.4 8.1 1 1 5 6 6 6 1 Baculovirus immediate-early protein (IE-0) zf-DBF PF07535.12 KFM71728.1 - 1.1e-05 25.4 42.5 1.9 8.7 0.2 9.5 10 0 0 10 10 9 2 DBF zinc finger Zf_RING PF16744.5 KFM71728.1 - 2.3e-05 24.4 39.6 4.1 7.6 0.1 9.2 1 1 7 8 8 8 1 KIAA1045 RING finger zf-FPG_IleRS PF06827.14 KFM71728.1 - 3.6e-05 23.5 22.0 1 9.3 0.0 8.4 9 0 0 9 9 9 2 Zinc finger found in FPG and IleRS zf-MYST PF17772.1 KFM71728.1 - 0.00027 20.5 45.0 1 9.0 0.3 9.0 3 3 6 9 9 9 3 MYST family zinc finger domain DUF2256 PF10013.9 KFM71728.1 - 0.00031 20.8 34.0 8 6.7 0.1 9.3 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) Amidohydro_1 PF01979.20 KFM71728.1 - 0.00061 19.2 14.8 4 6.6 0.1 5.8 1 1 6 7 7 7 1 Amidohydrolase family GAGA PF09237.11 KFM71728.1 - 0.00087 19.0 14.6 12 5.8 0.0 7.3 1 1 7 9 9 9 0 GAGA factor zinc-ribbons_6 PF07191.12 KFM71728.1 - 0.002 18.1 38.1 2.8 8.0 2.0 7.5 1 1 5 6 6 5 1 zinc-ribbons C1_1 PF00130.22 KFM71728.1 - 0.0038 17.1 42.3 0.62 10.0 2.1 7.6 1 1 3 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 KFM71728.1 - 0.0066 16.5 38.3 0.024 14.8 6.6 4.5 1 1 2 3 3 3 2 Putative ribonucleoprotein zinc-finger pf C4 type Complex1_49kDa PF00346.19 KFM71728.1 - 0.0096 15.0 4.5 1.3 8.1 0.1 2.9 1 1 4 5 5 5 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Tox-HNH-HHH PF15637.6 KFM71728.1 - 0.023 14.9 1.8 17 5.6 0.0 3.7 1 1 5 6 6 6 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif C1_4 PF07975.12 KFM71728.1 - 0.04 14.2 45.0 0.085 13.1 1.7 6.9 2 2 6 8 8 8 0 TFIIH C1-like domain zf_UBZ PF18439.1 KFM71728.1 - 0.059 13.0 34.8 4.4 7.0 0.1 9.0 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger DUF2039 PF10217.9 KFM71728.1 - 0.11 12.9 39.5 2.5 8.5 6.2 4.5 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2039) Mga PF05043.13 KFM71728.1 - 0.14 12.7 3.3 0.78 10.4 0.3 3.2 3 2 0 3 3 3 0 Mga helix-turn-helix domain zf-C2H2_2 PF12756.7 KFM71728.1 - 0.15 12.4 66.5 1.4 9.3 2.9 9.7 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM71728.1 - 0.16 12.0 0.3 0.16 12.0 0.3 6.5 5 2 1 7 7 7 0 Adenylate kinase, active site lid M-factor PF03855.13 KFM71728.1 - 0.4 10.9 5.9 85 3.4 0.0 4.7 5 0 0 5 5 4 0 M-factor TRAF6_Z2 PF18048.1 KFM71728.1 - 2.6 8.2 53.2 0.36 11.0 3.1 9.0 10 0 0 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 Zn-ribbon_8 PF09723.10 KFM71728.1 - 2.7 8.2 35.0 3.2 7.9 2.3 6.7 3 2 5 8 8 8 0 Zinc ribbon domain zf-Dof PF02701.15 KFM71728.1 - 3.9 7.7 27.0 23 5.2 0.0 7.8 3 1 4 7 7 7 0 Dof domain, zinc finger LIM PF00412.22 KFM71728.1 - 8.8 6.6 46.4 23 5.3 2.9 8.7 2 2 3 7 7 7 0 LIM domain zf-H2C2_2 PF13465.6 KFM71729.1 - 8.2e-12 45.0 14.0 3.1e-07 30.5 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71729.1 - 4.2e-11 42.7 12.8 1.1e-05 25.6 0.6 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 KFM71729.1 - 2.5e-09 37.2 10.4 0.00014 22.2 2.7 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM71729.1 - 1.9e-07 31.3 12.7 0.00075 20.1 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM71729.1 - 3e-06 27.1 4.8 0.014 15.3 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM71729.1 - 0.0025 17.6 3.5 0.23 11.4 0.1 2.7 3 0 0 3 3 2 2 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFM71729.1 - 0.0077 16.0 5.1 0.011 15.5 0.2 2.4 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-DBF PF07535.12 KFM71729.1 - 0.0099 16.0 5.4 0.74 10.0 1.5 2.4 2 0 0 2 2 2 2 DBF zinc finger zf-C2H2_9 PF16293.5 KFM71729.1 - 0.013 15.4 6.1 0.69 9.8 1.6 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 KFM71729.1 - 0.013 15.5 2.7 0.33 11.0 0.5 2.3 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 KFM71729.1 - 0.028 14.7 12.8 0.47 10.8 0.5 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-FPG_IleRS PF06827.14 KFM71729.1 - 0.029 14.2 0.6 0.49 10.3 0.3 2.5 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-Sec23_Sec24 PF04810.15 KFM71729.1 - 0.071 13.2 3.4 0.57 10.3 0.1 2.9 1 1 2 3 3 3 0 Sec23/Sec24 zinc finger Amidohydro_1 PF01979.20 KFM71729.1 - 0.099 11.9 1.1 1.8 7.8 0.1 1.9 1 1 1 2 2 2 0 Amidohydrolase family DUF2256 PF10013.9 KFM71729.1 - 0.16 12.1 4.6 4.3 7.5 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Di19 PF05605.12 KFM71729.1 - 0.17 12.2 9.0 0.92 9.9 9.0 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFM71729.1 - 0.79 9.4 3.8 5.8 6.6 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 KFM71729.1 - 1.3 9.6 7.3 1.6 9.2 0.8 2.9 3 1 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 KFM71729.1 - 1.5 9.2 12.1 3.5 8.0 0.5 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Vps39_2 PF10367.9 KFM71729.1 - 1.7 9.2 7.8 8.5 6.9 0.4 2.6 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 C1_4 PF07975.12 KFM71729.1 - 2.6 8.4 8.4 0.77 10.0 3.5 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain TRAF6_Z2 PF18048.1 KFM71729.1 - 4.3 7.5 12.2 2.4 8.3 2.4 2.9 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-MYST PF17772.1 KFM71729.1 - 5.5 6.7 9.5 0.55 9.9 0.6 2.5 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2H2 PF00096.26 KFM71731.1 - 7.6e-09 35.5 3.8 0.00023 21.4 0.6 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71731.1 - 5.5e-07 29.9 4.1 0.00066 20.3 0.6 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFM71731.1 - 0.0012 19.0 5.2 0.0014 18.8 5.2 1.0 1 0 0 1 1 1 1 Aberrant zinc-finger zf-BED PF02892.15 KFM71731.1 - 0.0016 18.4 0.9 0.0016 18.4 0.9 2.2 2 1 0 2 2 2 1 BED zinc finger zf-C2H2_jaz PF12171.8 KFM71731.1 - 0.0045 17.2 1.1 0.0045 17.2 1.1 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM71731.1 - 0.0084 16.1 5.0 0.31 11.1 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM71731.1 - 0.0093 16.3 4.6 0.03 14.7 1.2 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KFM71731.1 - 0.014 16.0 1.3 0.85 10.3 0.2 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain Med4 PF10018.9 KFM71731.1 - 0.081 12.6 0.5 0.09 12.4 0.5 1.0 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 zf-H2C2_2 PF13465.6 KFM71731.1 - 0.13 12.7 0.7 0.13 12.7 0.7 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Arf PF00025.21 KFM71734.1 - 6.1e-07 29.1 0.0 8.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFM71734.1 - 0.0088 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFM71734.1 - 0.019 14.1 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KFM71734.1 - 0.037 14.1 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KFM71734.1 - 0.061 13.6 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFM71734.1 - 0.081 13.5 0.0 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF533 PF04391.12 KFM71734.1 - 0.15 11.6 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) TniB PF05621.11 KFM71734.1 - 0.18 11.2 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein zf-C2H2 PF00096.26 KFM71735.1 - 8.3e-24 82.7 46.1 3.3e-05 24.1 3.0 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM71735.1 - 3.7e-16 58.7 48.8 1.2e-07 31.8 1.5 7.5 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM71735.1 - 1.3e-12 47.4 48.2 0.0095 16.7 3.0 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM71735.1 - 2.9e-05 23.7 36.3 2.9e-05 23.7 4.4 5.3 5 0 0 5 5 5 3 C2H2-type zinc-finger domain GAGA PF09237.11 KFM71735.1 - 0.0036 17.1 9.4 0.24 11.2 0.7 3.5 2 1 1 3 3 3 2 GAGA factor DUF3268 PF11672.8 KFM71735.1 - 0.0061 16.9 14.6 0.06 13.7 0.9 2.8 2 1 1 3 3 3 2 zinc-finger-containing domain zinc_ribbon_2 PF13240.6 KFM71735.1 - 0.084 12.6 1.8 0.44 10.3 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_7 PF15269.6 KFM71735.1 - 0.31 11.2 17.0 0.23 11.5 1.2 3.3 2 1 1 3 3 3 0 Zinc-finger BolA PF01722.18 KFM71735.1 - 0.62 10.4 3.3 35 4.8 0.0 2.7 2 0 0 2 2 2 0 BolA-like protein zf-C2H2_jaz PF12171.8 KFM71735.1 - 2 8.8 31.4 1.7 9.0 2.0 5.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Merozoite_SPAM PF07133.11 KFM71735.1 - 5.4 7.0 32.9 8.7 6.3 32.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Peptidase_M13 PF01431.21 KFM71737.1 - 3.6e-13 49.6 0.3 7.5e-13 48.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM71737.1 - 2e-12 47.5 2.0 3.3e-12 46.8 2.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 HTH_Tnp_Tc3_2 PF01498.18 KFM71738.1 - 4.3e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71738.1 - 1.1e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71738.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71738.1 - 0.0025 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71738.1 - 0.025 14.7 0.4 0.084 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM71738.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Endonuclease_7 PF02945.15 KFM71739.1 - 2.9e-07 30.3 0.1 9.4e-07 28.7 0.1 1.8 1 0 0 1 1 1 1 Recombination endonuclease VII zf-MYST PF17772.1 KFM71739.1 - 0.0019 17.8 0.4 0.0084 15.7 0.4 2.2 1 0 0 1 1 1 1 MYST family zinc finger domain zf-C2H2_8 PF15909.5 KFM71739.1 - 0.2 11.9 1.4 0.66 10.3 1.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon DDE_3 PF13358.6 KFM71740.1 - 1.4e-10 41.1 0.0 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71740.1 - 1.7e-09 37.8 0.1 4.7e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71740.1 - 5.6e-06 26.9 2.4 5.6e-06 26.9 2.4 2.2 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM71740.1 - 0.00056 19.7 0.6 0.042 13.7 0.1 2.5 2 0 0 2 2 2 1 MarR family HTH_3 PF01381.22 KFM71740.1 - 0.00058 19.9 0.8 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 KFM71740.1 - 0.0011 19.1 2.6 0.012 15.7 0.3 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.18 KFM71740.1 - 0.0067 16.4 0.0 0.016 15.1 0.0 1.6 1 1 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFM71740.1 - 0.012 15.4 1.5 0.24 11.3 0.1 2.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM71740.1 - 0.017 15.1 1.8 0.063 13.3 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM71740.1 - 0.035 13.7 2.0 0.41 10.2 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 KFM71740.1 - 0.1 13.1 0.4 18 5.9 0.1 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain TrmB PF01978.19 KFM71740.1 - 0.14 12.1 0.1 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Tnp_Tc3_2 PF01498.18 KFM71741.1 - 1.8e-19 69.8 3.6 6.2e-19 68.0 2.1 2.4 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71741.1 - 5.5e-16 58.6 0.0 2.6e-15 56.5 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM71741.1 - 2.2e-07 30.9 0.4 0.00015 21.8 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM71741.1 - 3.7e-07 30.7 4.4 3.9e-07 30.6 2.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71741.1 - 1.1e-06 28.7 2.3 8.2e-05 22.7 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71741.1 - 2e-06 27.4 3.3 2.7e-05 23.8 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM71741.1 - 2.5e-06 27.4 0.7 4.3e-05 23.4 0.1 2.6 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM71741.1 - 8.9e-05 22.3 2.6 0.0018 18.1 0.0 3.4 3 1 1 4 4 4 1 MarR family HTH_Crp_2 PF13545.6 KFM71741.1 - 0.001 19.0 0.3 0.018 15.0 0.0 2.5 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM71741.1 - 0.018 14.7 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM71741.1 - 0.058 13.5 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM71741.1 - 0.096 12.9 0.1 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 KFM71741.1 - 0.099 12.7 0.2 32 4.7 0.0 3.1 3 0 0 3 3 3 0 HTH domain Anti-TRAP PF15777.5 KFM71741.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein HTH_30 PF13556.6 KFM71741.1 - 0.29 11.0 3.9 1.5 8.6 0.0 3.1 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM71741.1 - 1.2 8.6 3.6 7.6 6.0 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Retrotrans_gag PF03732.17 KFM71742.1 - 0.00098 19.4 1.8 0.0016 18.7 0.5 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 KFM71742.1 - 0.0053 16.4 0.3 0.0094 15.6 0.3 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4848 PF16140.5 KFM71742.1 - 0.11 12.0 2.7 0.2 11.2 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4848) His_Phos_2 PF00328.22 KFM71744.1 - 1.4e-28 100.3 0.6 5e-28 98.5 0.6 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 KFM71744.1 - 0.0014 18.3 0.0 0.0062 16.3 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DDE_3 PF13358.6 KFM71745.1 - 8.5e-10 38.6 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HypA PF01155.19 KFM71746.1 - 0.0023 17.9 0.6 0.0024 17.9 0.6 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2321 PF10083.9 KFM71746.1 - 0.24 11.0 8.0 0.31 10.7 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2HC_2 PF13913.6 KFM71747.1 - 2.1e-08 33.8 1.2 3.6e-08 33.1 1.2 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KFM71747.1 - 0.0038 17.6 0.1 0.012 16.1 0.1 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type Vezatin PF12632.7 KFM71747.1 - 0.0063 15.9 0.1 0.0072 15.7 0.1 1.1 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes zf-C2H2_4 PF13894.6 KFM71747.1 - 0.056 14.3 0.9 0.11 13.4 0.2 1.9 2 1 0 2 2 2 0 C2H2-type zinc finger Chitin_bind_4 PF00379.23 KFM71749.1 - 7.8e-20 71.1 18.5 3.2e-12 46.8 5.2 2.6 2 0 0 2 2 2 2 Insect cuticle protein SPC12 PF06645.13 KFM71750.1 - 0.061 13.4 0.7 0.1 12.7 0.7 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) CBP_BcsF PF11120.8 KFM71750.1 - 0.069 13.3 0.9 0.069 13.3 0.9 1.6 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsF LapA_dom PF06305.11 KFM71750.1 - 1.3 8.9 9.0 1.2 9.0 1.3 2.2 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3867 PF12983.7 KFM71751.1 - 0.054 13.5 3.2 0.062 13.3 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) EMC3_TMCO1 PF01956.16 KFM71751.1 - 2.9 7.6 5.4 3 7.5 5.4 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Peptidase_S49_N PF08496.10 KFM71751.1 - 3.1 7.8 8.2 3 7.9 8.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Thyroglobulin_1 PF00086.18 KFM71752.1 - 7.9e-22 76.7 38.4 2.4e-10 39.9 1.1 4.7 5 0 0 5 5 5 4 Thyroglobulin type-1 repeat amfpi-1 PF12190.8 KFM71752.1 - 0.025 15.2 11.9 0.025 15.2 11.9 3.2 3 1 1 4 4 4 0 Fungal protease inhibitor HTH_Tnp_Tc3_2 PF01498.18 KFM71753.1 - 1.5e-17 63.5 1.4 4.5e-16 58.9 2.2 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71753.1 - 9.6e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Chitin_bind_4 PF00379.23 KFM71758.1 - 6.5e-12 45.8 6.0 1.3e-11 44.9 6.0 1.5 1 0 0 1 1 1 1 Insect cuticle protein PIF1 PF05970.14 KFM71761.1 - 1.1e-07 31.4 0.1 1.2e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Chitin_bind_4 PF00379.23 KFM71762.1 - 1e-11 45.2 5.0 2e-11 44.3 5.0 1.5 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM71763.1 - 9e-11 42.1 4.8 1.4e-10 41.6 4.8 1.3 1 0 0 1 1 1 1 Insect cuticle protein Membralin PF09746.9 KFM71764.1 - 0.22 10.6 3.5 0.34 9.9 3.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein PA26 PF04636.13 KFM71764.1 - 8.6 5.2 7.1 11 4.7 7.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Chitin_bind_4 PF00379.23 KFM71765.1 - 1.7e-22 79.7 19.7 6.4e-11 42.6 5.9 2.5 2 0 0 2 2 2 2 Insect cuticle protein THB PF18362.1 KFM71765.1 - 0.001 18.6 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 Tri-helix bundle domain DUF903 PF06004.12 KFM71765.1 - 0.14 12.1 0.3 30 4.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) Chitin_bind_4 PF00379.23 KFM71766.1 - 9.2e-12 45.3 4.9 1.5e-11 44.6 4.9 1.4 1 0 0 1 1 1 1 Insect cuticle protein DDE_Tnp_1_7 PF13843.6 KFM71767.1 - 2.5e-35 122.4 0.1 1.1e-22 80.8 0.0 2.1 1 1 1 2 2 2 2 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM71767.1 - 0.0012 18.6 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 KFM71768.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71768.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ig_3 PF13927.6 KFM71770.1 - 2.8e-11 43.9 0.2 5.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM71770.1 - 2.4e-07 31.0 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM71770.1 - 3e-06 27.2 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM71770.1 - 4.8e-06 26.7 0.0 0.049 13.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain PKD PF00801.20 KFM71770.1 - 0.00043 20.1 0.3 0.00068 19.4 0.3 1.3 1 0 0 1 1 1 1 PKD domain V-set PF07686.17 KFM71770.1 - 0.012 15.8 0.0 1.8 8.8 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin V-set domain Prok-E2_A PF14457.6 KFM71770.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A Ig_C17orf99 PF17736.1 KFM71770.1 - 0.044 13.8 0.0 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 C17orf99 Ig domain Izumo-Ig PF16706.5 KFM71770.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain RCC1_2 PF13540.6 KFM71770.1 - 0.061 13.1 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Ig_5 PF16681.5 KFM71770.1 - 0.08 13.4 0.1 2.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM71770.1 - 0.097 12.9 0.2 0.33 11.2 0.1 1.9 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Ig_3 PF13927.6 KFM71771.1 - 1.3e-16 61.0 0.0 2e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM71771.1 - 2.8e-14 52.9 0.0 5.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFM71771.1 - 2.9e-13 49.8 0.0 1.7e-06 28.1 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM71771.1 - 3.2e-12 46.6 0.0 9.9e-06 25.8 0.1 2.4 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM71771.1 - 1.5e-11 44.2 0.0 0.00014 21.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Lep_receptor_Ig PF06328.11 KFM71771.1 - 0.00024 21.0 0.3 0.0086 16.0 0.1 2.8 3 0 0 3 3 3 1 Ig-like C2-type domain MLANA PF14991.6 KFM71774.1 - 0.0017 18.6 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein melan-A DUF3611 PF12263.8 KFM71774.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) TMEM100 PF16311.5 KFM71774.1 - 0.18 11.4 0.2 0.37 10.4 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 TMEM154 PF15102.6 KFM71774.1 - 0.33 10.9 0.0 0.33 10.9 0.0 3.3 5 0 0 5 5 5 0 TMEM154 protein family EGF PF00008.27 KFM71775.1 - 5e-10 39.5 8.0 9.1e-10 38.7 8.0 1.4 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 KFM71775.1 - 4.4e-05 23.8 5.8 8.7e-05 22.8 5.8 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFM71775.1 - 0.00019 21.9 4.7 0.00019 21.9 4.7 1.8 2 0 0 2 2 2 1 Human growth factor-like EGF EGF_CA PF07645.15 KFM71775.1 - 0.00034 20.7 2.5 0.00068 19.8 2.5 1.6 1 0 0 1 1 1 1 Calcium-binding EGF domain Laminin_G_2 PF02210.24 KFM71775.1 - 0.017 15.7 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain EGF_3 PF12947.7 KFM71775.1 - 0.048 13.9 3.9 0.089 13.0 3.9 1.5 1 0 0 1 1 1 0 EGF domain FXa_inhibition PF14670.6 KFM71775.1 - 0.19 12.0 4.5 0.51 10.7 4.5 1.7 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFM71776.1 - 0.018 15.4 5.3 0.018 15.4 5.3 2.9 3 0 0 3 3 3 0 EGF-like domain Laminin_EGF PF00053.24 KFM71776.1 - 0.17 12.1 14.2 0.23 11.6 3.4 2.5 1 1 1 2 2 2 0 Laminin EGF domain EGF_3 PF12947.7 KFM71776.1 - 4.3 7.6 12.9 3.2 8.0 0.2 2.9 3 0 0 3 3 3 0 EGF domain Cadherin PF00028.17 KFM71778.1 - 8.4e-19 67.8 0.0 2.4e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 Cadherin domain Cadherin_3 PF16184.5 KFM71778.1 - 0.0095 15.9 0.2 0.025 14.6 0.2 1.7 1 1 0 1 1 1 1 Cadherin-like Cadherin_4 PF17803.1 KFM71778.1 - 0.1 13.3 3.1 0.29 11.8 3.0 2.0 1 1 0 1 1 1 0 Bacterial cadherin-like domain SCP2_2 PF13530.6 KFM71778.1 - 0.17 12.3 0.0 0.46 10.9 0.0 1.7 1 1 1 2 2 2 0 Sterol carrier protein domain Cadherin PF00028.17 KFM71779.1 - 1.7e-30 105.3 0.1 1.9e-15 57.1 0.1 3.1 3 0 0 3 3 3 3 Cadherin domain Cadherin_3 PF16184.5 KFM71779.1 - 1.5e-05 25.0 0.2 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 Cadherin-like Cadherin_4 PF17803.1 KFM71779.1 - 0.0038 17.8 0.4 0.76 10.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial cadherin-like domain Cadherin_2 PF08266.12 KFM71779.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Cadherin-like Cadherin PF00028.17 KFM71780.1 - 0.0022 18.4 0.1 0.0023 18.3 0.1 1.0 1 0 0 1 1 1 1 Cadherin domain Cadherin PF00028.17 KFM71781.1 - 6.5e-67 222.0 8.7 1.6e-19 70.1 0.1 5.1 5 0 0 5 5 5 5 Cadherin domain Cadherin_pro PF08758.11 KFM71781.1 - 1.9e-08 34.3 0.0 0.00065 19.8 0.0 4.1 4 0 0 4 4 4 1 Cadherin prodomain like Cadherin_2 PF08266.12 KFM71781.1 - 2.8e-06 27.1 0.1 3.6 7.5 0.0 4.3 4 1 0 4 4 4 3 Cadherin-like RET_CLD1 PF17756.1 KFM71781.1 - 1.5e-05 25.3 0.0 0.64 10.3 0.0 3.8 2 1 1 3 3 3 2 RET Cadherin like domain 1 NAGLU_N PF12971.7 KFM71781.1 - 0.023 14.5 0.1 8.5 6.2 0.0 2.8 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Cadherin_4 PF17803.1 KFM71781.1 - 0.036 14.7 4.4 0.25 12.0 1.1 3.2 4 0 0 4 4 4 0 Bacterial cadherin-like domain Big_9 PF17963.1 KFM71781.1 - 0.14 12.9 8.9 0.26 12.1 2.0 3.1 4 0 0 4 4 4 0 Bacterial Ig domain Cadherin PF00028.17 KFM71782.1 - 1e-22 80.4 0.2 9.7e-20 70.8 0.0 2.1 2 0 0 2 2 2 2 Cadherin domain HTH_Tnp_Tc3_2 PF01498.18 KFM71784.1 - 2.2e-16 59.8 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71784.1 - 9.3e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Cadherin PF00028.17 KFM71785.1 - 1.1e-65 218.1 0.0 1e-17 64.3 0.0 4.0 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.12 KFM71785.1 - 2.1e-05 24.3 0.0 0.41 10.5 0.0 3.8 4 1 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFM71785.1 - 0.00022 21.2 0.7 0.19 11.7 0.1 3.7 4 2 0 4 4 4 2 Cadherin-like RET_CLD1 PF17756.1 KFM71785.1 - 0.039 14.2 0.0 5.6 7.3 0.0 3.3 2 1 1 3 3 3 0 RET Cadherin like domain 1 PFU PF09070.11 KFM71785.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Cadherin PF00028.17 KFM71786.1 - 1.4e-07 31.8 0.0 2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Cadherin domain Cadherin PF00028.17 KFM71787.1 - 3.4e-49 165.2 2.1 1.2e-16 61.0 0.0 5.2 5 0 0 5 5 5 4 Cadherin domain Cadherin_2 PF08266.12 KFM71787.1 - 0.057 13.3 0.0 1.9 8.4 0.0 3.2 3 1 1 4 4 4 0 Cadherin-like Cadherin_4 PF17803.1 KFM71787.1 - 8.9 7.0 12.6 2.3 8.9 0.0 3.9 4 1 0 4 4 4 0 Bacterial cadherin-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71788.1 - 7.5e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71788.1 - 1e-14 54.5 0.1 1.2e-13 51.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71788.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71788.1 - 0.0033 17.2 0.1 0.17 11.7 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71788.1 - 0.0092 16.1 0.1 0.04 14.1 0.1 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM71788.1 - 0.045 13.8 2.6 0.046 13.7 0.3 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM71789.1 - 5.5e-16 58.6 3.5 6e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71789.1 - 4.2e-13 49.3 0.0 7.2e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71789.1 - 2.3e-07 30.5 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71789.1 - 0.0029 17.4 0.6 0.008 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71789.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71790.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71790.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71790.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71790.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71790.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71791.1 - 7.7e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71791.1 - 4.6e-15 55.6 0.1 5.6e-14 52.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71791.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71791.1 - 0.0023 17.7 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71791.1 - 0.012 15.8 0.1 0.065 13.4 0.1 2.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71791.1 - 0.035 14.1 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix MBA1 PF07961.11 KFM71792.1 - 0.0048 16.0 0.2 0.0048 16.0 0.2 1.1 1 0 0 1 1 1 1 MBA1-like protein YfhO PF09586.10 KFM71793.1 - 0.21 9.8 4.0 0.28 9.4 4.0 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO PHD PF00628.29 KFM71794.1 - 4.9e-11 42.4 11.6 4.9e-11 42.4 11.6 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KFM71794.1 - 3e-08 33.9 27.4 3.9e-06 27.1 6.7 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 KFM71794.1 - 1.4e-05 24.8 6.2 1.4e-05 24.8 6.2 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM71794.1 - 1.8e-05 24.5 7.7 1.8e-05 24.5 7.7 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM71794.1 - 6e-05 23.0 9.4 6e-05 23.0 9.4 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM71794.1 - 0.0022 17.8 7.4 0.0022 17.8 7.4 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM71794.1 - 0.0041 17.1 6.3 0.0041 17.1 6.3 3.6 2 2 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFM71794.1 - 0.0043 17.3 4.3 0.0043 17.3 4.3 3.4 3 1 0 3 3 3 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFM71794.1 - 2.4 8.1 23.7 0.045 13.6 8.2 3.9 3 2 1 4 4 4 0 Prokaryotic RING finger family 4 Pep_M12B_propep PF01562.19 KFM71796.1 - 7e-09 36.0 1.7 2e-08 34.5 0.0 2.3 2 1 0 3 3 3 1 Reprolysin family propeptide YkyA PF10368.9 KFM71796.1 - 0.014 15.1 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Disintegrin PF00200.23 KFM71797.1 - 2e-10 41.3 20.3 2e-10 41.3 20.3 1.6 2 0 0 2 2 2 1 Disintegrin Glycos_transf_3 PF00591.21 KFM71800.1 - 9.6e-25 87.6 0.4 1.2e-24 87.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 KFM71800.1 - 0.013 15.2 0.1 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Acetyltransf_18 PF18014.1 KFM71801.1 - 2.6e-17 62.8 0.0 8.4e-17 61.2 0.0 1.8 2 1 2 4 4 4 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM71801.1 - 9.9e-07 29.0 0.1 2.6e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM71801.1 - 1.4e-06 28.3 0.0 9e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM71801.1 - 0.00011 22.5 0.1 0.0008 19.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM71801.1 - 0.0035 17.3 0.0 0.095 12.7 0.0 2.5 2 1 0 2 2 2 1 FR47-like protein RINGv PF12906.7 KFM71804.1 - 1.7e-14 53.7 10.5 2.9e-14 52.9 10.5 1.4 1 0 0 1 1 1 1 RING-variant domain DUF2517 PF10725.9 KFM71804.1 - 0.001 18.8 0.6 0.0036 17.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2517) zf-RING_2 PF13639.6 KFM71804.1 - 0.0024 18.1 6.2 0.0053 17.1 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KFM71804.1 - 0.013 15.7 5.7 0.025 14.7 5.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFM71804.1 - 0.073 12.9 6.0 0.17 11.7 6.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CSL PF05207.13 KFM71804.1 - 0.095 12.4 1.2 0.25 11.1 1.2 1.6 1 0 0 1 1 1 0 CSL zinc finger PHD PF00628.29 KFM71804.1 - 0.21 11.5 9.1 0.36 10.8 9.1 1.4 1 0 0 1 1 1 0 PHD-finger TRAF6_Z2 PF18048.1 KFM71804.1 - 4.4 7.5 5.8 0.91 9.7 0.5 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 DDE_3 PF13358.6 KFM71805.1 - 1.6e-15 57.1 0.0 2.9e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71805.1 - 7.1e-14 51.8 2.8 8.2e-14 51.6 0.8 2.1 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 KFM71805.1 - 1.2e-05 25.3 3.6 0.00073 19.6 0.4 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71805.1 - 0.0002 21.1 7.0 0.0021 17.8 0.2 3.3 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM71805.1 - 0.00029 20.8 1.2 0.0054 16.7 0.2 2.6 2 0 0 2 2 2 1 Winged helix-turn helix PAX PF00292.18 KFM71805.1 - 0.00031 20.7 0.3 0.00067 19.6 0.3 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 KFM71805.1 - 0.00031 21.3 5.0 0.00031 21.3 5.0 3.3 3 1 0 3 3 3 1 Homeodomain-like domain HTH_37 PF13744.6 KFM71805.1 - 0.0046 16.9 0.2 0.095 12.7 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_22 PF13309.6 KFM71805.1 - 0.073 13.2 0.1 0.24 11.5 0.1 1.9 1 0 0 1 1 1 0 HTH domain HTH_33 PF13592.6 KFM71805.1 - 0.09 12.4 0.2 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix HTH_17 PF12728.7 KFM71805.1 - 0.098 12.9 0.2 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF5447 PF17525.2 KFM71805.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5447) MarR_2 PF12802.7 KFM71805.1 - 0.14 12.1 0.4 0.14 12.1 0.4 2.9 3 0 0 3 3 3 0 MarR family HTH_3 PF01381.22 KFM71805.1 - 0.14 12.2 1.4 1.8 8.7 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix HTH_7 PF02796.15 KFM71805.1 - 0.18 11.9 1.6 0.77 9.9 1.6 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase COPIIcoated_ERV PF07970.12 KFM71806.1 - 4.4e-36 124.8 0.3 7.6e-36 124.0 0.3 1.3 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter CRAL_TRIO PF00650.20 KFM71807.1 - 0.0044 16.8 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain DUF842 PF05811.13 KFM71808.1 - 0.0014 18.3 2.8 0.0017 18.0 2.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) ApoLp-III PF07464.11 KFM71808.1 - 0.0019 18.3 5.6 0.0024 18.0 5.6 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF1640 PF07798.11 KFM71808.1 - 0.0025 17.9 8.4 0.0029 17.7 8.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) CCDC154 PF15450.6 KFM71808.1 - 0.0037 15.9 8.6 0.0039 15.8 8.6 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 Apolipoprotein PF01442.18 KFM71808.1 - 0.0046 16.9 7.8 0.0053 16.7 7.8 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Spectrin PF00435.21 KFM71808.1 - 0.011 16.2 7.8 0.018 15.5 7.8 1.4 1 1 0 1 1 1 0 Spectrin repeat Spore_III_AB PF09548.10 KFM71808.1 - 0.012 15.7 4.4 0.015 15.4 4.4 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Atg14 PF10186.9 KFM71808.1 - 0.019 14.1 4.2 0.021 13.9 4.2 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Strep_SA_rep PF06696.11 KFM71808.1 - 0.022 14.7 8.1 0.21 11.6 0.2 3.2 3 1 0 3 3 3 0 Streptococcal surface antigen repeat EKAL PF17986.1 KFM71808.1 - 0.033 14.2 4.2 0.033 14.2 4.2 1.5 2 0 0 2 2 1 0 EMP3-KAHRP-like N-terminal domain RRF PF01765.19 KFM71808.1 - 0.047 13.6 11.1 0.052 13.5 11.1 1.0 1 0 0 1 1 1 0 Ribosome recycling factor Focal_AT PF03623.13 KFM71808.1 - 0.057 13.4 4.2 0.074 13.0 4.2 1.3 1 1 0 1 1 1 0 Focal adhesion targeting region dCache_2 PF08269.11 KFM71808.1 - 0.066 12.4 4.2 0.069 12.3 4.2 1.0 1 0 0 1 1 1 0 Cache domain Halo_GVPC PF05465.13 KFM71808.1 - 0.068 13.4 4.4 8.4 6.8 0.2 3.0 2 1 1 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat Spc7 PF08317.11 KFM71808.1 - 0.07 12.0 9.6 0.081 11.8 9.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein WXG100 PF06013.12 KFM71808.1 - 0.082 13.1 5.6 3.7 7.9 5.8 2.0 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Cluap1 PF10234.9 KFM71808.1 - 0.1 12.0 8.2 0.12 11.8 8.2 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 COG2 PF06148.11 KFM71808.1 - 0.11 12.6 9.0 0.15 12.1 8.0 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.13 KFM71808.1 - 0.12 12.9 4.5 0.23 12.1 4.5 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF148 PF02520.17 KFM71808.1 - 0.2 11.7 8.6 2.1 8.5 8.6 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF148 Prominin PF05478.11 KFM71808.1 - 0.3 9.0 3.5 0.29 9.1 3.5 1.0 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.8 KFM71808.1 - 0.3 8.5 8.9 0.35 8.3 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) T3SS_needle_F PF09392.10 KFM71808.1 - 0.3 11.3 4.2 2.1 8.6 1.4 2.2 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Golgin_A5 PF09787.9 KFM71808.1 - 0.32 10.4 10.9 0.38 10.2 10.9 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 OmpH PF03938.14 KFM71808.1 - 0.34 11.2 14.4 0.43 10.9 14.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BCAS2 PF05700.11 KFM71808.1 - 0.4 10.4 6.8 0.48 10.1 6.8 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) tRNA_bind_2 PF13725.6 KFM71808.1 - 0.43 10.2 10.1 0.48 10.1 10.1 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain HisKA_3 PF07730.13 KFM71808.1 - 0.68 10.5 3.5 2.6 8.6 1.0 2.1 1 1 1 2 2 2 0 Histidine kinase Lectin_N PF03954.14 KFM71808.1 - 0.95 9.2 4.0 1.2 8.9 4.0 1.4 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF349 PF03993.12 KFM71808.1 - 1.2 9.4 8.4 1.5 9.2 8.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) TMPIT PF07851.13 KFM71808.1 - 1.3 8.1 7.9 1.5 8.0 7.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein LPP PF04728.13 KFM71808.1 - 4.5 7.7 7.1 3.2e+02 1.8 7.1 2.7 1 1 0 1 1 1 0 Lipoprotein leucine-zipper YtxH PF12732.7 KFM71808.1 - 5.2 7.7 12.8 36 5.0 12.8 2.0 1 1 0 1 1 1 0 YtxH-like protein DDE_Tnp_1_7 PF13843.6 KFM71809.1 - 2.4e-52 178.4 0.0 2.8e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 PBECR4 PF18813.1 KFM71811.1 - 0.023 14.9 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 DDE_3 PF13358.6 KFM71812.1 - 4.6e-16 58.9 0.1 6.3e-15 55.2 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71812.1 - 7.2e-16 58.2 6.5 1.5e-15 57.2 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71812.1 - 0.00064 20.3 1.7 0.00064 20.3 1.7 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71812.1 - 0.0016 18.2 0.1 0.073 12.9 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71812.1 - 0.018 15.1 0.2 0.078 13.1 0.2 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71812.1 - 0.02 14.9 0.4 0.02 14.9 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM71813.1 - 2.3e-16 59.8 2.9 4.2e-16 58.9 2.2 1.8 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM71813.1 - 2.3e-07 30.5 0.2 5.5e-07 29.2 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain DDE_3 PF13358.6 KFM71813.1 - 0.00056 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM71813.1 - 0.0019 17.9 0.6 0.0059 16.4 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71813.1 - 0.02 15.0 0.4 0.071 13.2 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain ALMS_motif PF15309.6 KFM71814.1 - 0.00072 20.0 4.5 0.0018 18.8 4.5 1.7 1 0 0 1 1 1 1 ALMS motif DUF771 PF05595.11 KFM71814.1 - 0.017 15.1 4.1 0.04 13.9 0.0 3.5 4 1 1 5 5 5 0 Domain of unknown function (DUF771) SEA PF01390.20 KFM71815.1 - 0.04 14.0 0.4 0.066 13.3 0.4 1.5 1 1 0 1 1 1 0 SEA domain MAM PF00629.23 KFM71816.1 - 4.9e-80 267.1 4.3 2e-22 79.9 0.0 4.0 4 0 0 4 4 4 4 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 KFM71818.1 - 1.8e-08 34.5 12.6 2.1e-08 34.3 11.7 1.6 1 1 0 1 1 1 1 Low-density lipoprotein receptor domain class A HTH_38 PF13936.6 KFM71819.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM71820.1 - 6.7e-16 58.3 6.5 1.7e-15 57.0 6.5 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71820.1 - 9.3e-15 54.7 0.1 1.2e-13 51.1 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71820.1 - 0.00085 19.9 1.5 0.00085 19.9 1.5 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71820.1 - 0.0037 17.0 0.9 0.13 12.1 0.0 3.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_29 PF13551.6 KFM71820.1 - 0.041 13.9 0.4 0.041 13.9 0.4 2.7 3 0 0 3 3 3 0 Winged helix-turn helix DDE_3 PF13358.6 KFM71821.1 - 1.6e-07 31.2 0.0 2.1e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2564 PF10819.8 KFM71824.1 - 0.075 13.4 6.8 0.36 11.3 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) Erp_C PF06780.11 KFM71824.1 - 0.1 12.6 2.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Erp protein C-terminus TMF_TATA_bd PF12325.8 KFM71824.1 - 0.18 12.0 12.1 2.1 8.6 0.1 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding RIC3 PF15361.6 KFM71824.1 - 0.19 12.1 0.8 0.36 11.2 0.8 1.6 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF1090 PF06476.12 KFM71824.1 - 2.1 8.5 14.3 0.11 12.6 6.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1090) Tnp_P_element_C PF12596.8 KFM71825.1 - 0.023 15.2 0.1 0.069 13.7 0.0 1.7 1 1 0 2 2 2 0 87kDa Transposase Carbpep_Y_N PF05388.11 KFM71825.1 - 0.042 14.4 0.0 0.073 13.6 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide PgaD PF13994.6 KFM71826.1 - 0.055 13.5 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 PgaD-like protein Ribosomal_L36 PF00444.18 KFM71826.1 - 0.23 11.7 1.8 0.24 11.6 0.3 1.8 2 0 0 2 2 2 0 Ribosomal protein L36 SieB PF14163.6 KFM71827.1 - 0.024 14.1 0.1 0.025 14.1 0.1 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B CAF-1_p150 PF11600.8 KFM71829.1 - 0.096 12.4 18.1 0.09 12.5 18.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3807 PF12720.7 KFM71829.1 - 0.25 11.6 8.5 0.24 11.6 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) WD40 PF00400.32 KFM71830.1 - 4e-17 62.3 10.0 7e-08 33.0 0.2 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM71830.1 - 0.00044 20.5 1.2 3.6 8.0 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM71830.1 - 0.051 12.9 0.2 6.3 6.0 0.0 3.0 3 0 0 3 3 3 0 WD40-like domain Tli4_N PF18443.1 KFM71831.1 - 0.028 14.8 0.8 0.029 14.7 0.8 1.1 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain AAA_32 PF13654.6 KFM71831.1 - 0.037 12.8 1.2 0.034 13.0 1.2 1.0 1 0 0 1 1 1 0 AAA domain LMSTEN PF07988.12 KFM71831.1 - 0.11 12.0 3.6 0.14 11.7 3.6 1.2 1 0 0 1 1 1 0 LMSTEN motif AI-2E_transport PF01594.16 KFM71831.1 - 0.23 10.6 0.2 0.25 10.5 0.2 1.0 1 0 0 1 1 1 0 AI-2E family transporter HTH_Tnp_Tc3_2 PF01498.18 KFM71832.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71832.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71832.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71832.1 - 0.0023 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71832.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain TPR_MalT PF17874.1 KFM71834.1 - 0.14 11.5 0.1 0.2 11.0 0.0 1.4 2 0 0 2 2 2 0 MalT-like TPR region DUF4688 PF15752.5 KFM71834.1 - 0.19 10.9 0.0 0.19 10.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) Pkinase PF00069.25 KFM71835.1 - 1e-28 100.4 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM71835.1 - 1.7e-18 66.8 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM71835.1 - 1.2e-09 37.5 0.1 2.1e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM71835.1 - 0.00019 21.4 0.2 0.00066 19.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFM71835.1 - 0.029 13.3 0.2 0.05 12.6 0.2 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFM71835.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ASFV_J13L PF05568.11 KFM71835.1 - 0.71 9.6 6.2 1.1 9.0 6.2 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein CTP_transf_3 PF02348.19 KFM71836.1 - 2.4e-33 115.9 0.0 3e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 KFM71836.1 - 5.4e-06 26.8 0.0 6.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain PH PF00169.29 KFM71837.1 - 4.7e-24 84.9 0.1 5.4e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFM71837.1 - 1.2e-05 25.7 5.6 0.04 14.3 0.9 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KFM71837.1 - 9e-05 22.7 0.1 0.063 13.6 0.1 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain ArfGap PF01412.18 KFM71837.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH_2 PF08458.10 KFM71837.1 - 0.13 12.7 0.0 1.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Plant pleckstrin homology-like region 3HCDH_N PF02737.18 KFM71838.1 - 8e-64 214.8 0.6 9.3e-64 214.6 0.6 1.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFM71838.1 - 1.1e-06 28.1 0.3 2.1e-06 27.2 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KFM71838.1 - 2.6e-06 27.7 0.6 1.8e-05 25.0 0.6 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KFM71838.1 - 1.6e-05 24.3 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KFM71838.1 - 2.2e-05 24.1 0.8 5.6e-05 22.8 0.8 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH PF00725.22 KFM71838.1 - 5.2e-05 23.8 0.2 0.00017 22.1 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain F420_oxidored PF03807.17 KFM71838.1 - 6.2e-05 23.5 1.2 0.0012 19.4 1.2 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KFM71838.1 - 8.5e-05 22.6 0.4 0.00023 21.2 0.4 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 KFM71838.1 - 0.00042 20.8 0.9 0.00095 19.7 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 KFM71838.1 - 0.00073 19.2 0.1 0.0012 18.4 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KFM71838.1 - 0.0009 19.5 0.2 0.0023 18.2 0.2 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KFM71838.1 - 0.0026 17.2 0.1 0.0047 16.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.15 KFM71838.1 - 0.006 16.4 0.8 0.011 15.6 0.3 1.6 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NAD_binding_7 PF13241.6 KFM71838.1 - 0.019 15.4 0.2 0.035 14.6 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NES_C_h PF18208.1 KFM71838.1 - 0.02 15.2 1.6 0.068 13.4 0.4 2.1 1 1 1 2 2 2 0 Nicking enzyme C-terminal middle helical domain GIDA PF01134.22 KFM71838.1 - 0.033 13.3 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 KFM71838.1 - 0.038 14.2 0.1 0.08 13.2 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 KFM71838.1 - 0.047 13.1 0.1 0.067 12.6 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Pex19 PF04614.12 KFM71838.1 - 0.048 13.4 0.1 0.071 12.9 0.1 1.2 1 0 0 1 1 1 0 Pex19 protein family Methyltransf_25 PF13649.6 KFM71838.1 - 0.065 13.9 0.0 0.17 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain ApbA PF02558.16 KFM71838.1 - 0.076 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_12 PF08242.12 KFM71838.1 - 0.077 13.8 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DAO PF01266.24 KFM71838.1 - 0.084 12.4 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM71838.1 - 0.18 12.0 0.1 0.4 11.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KFM71838.1 - 1 9.4 4.1 16 5.5 4.1 2.3 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TraG_N PF07916.11 KFM71839.1 - 0.7 8.7 21.3 0.86 8.4 21.3 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF3810 PF12725.7 KFM71839.1 - 0.87 8.9 12.5 1 8.7 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) HTH_Tnp_Tc3_2 PF01498.18 KFM71840.1 - 5.2e-15 55.5 0.6 5.2e-15 55.5 0.6 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71840.1 - 1.9e-10 40.7 0.0 3.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 KFM71840.1 - 1.1e-05 25.5 3.8 0.00043 20.4 0.3 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.18 KFM71840.1 - 5.1e-05 23.2 0.1 0.0001 22.2 0.1 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 KFM71840.1 - 0.0001 22.8 5.0 0.00025 21.6 5.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KFM71840.1 - 0.0048 16.3 2.9 1.7 8.1 0.5 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 KFM71840.1 - 0.013 15.4 2.9 0.031 14.1 0.1 2.2 2 0 0 2 2 2 0 MarR family HTH_22 PF13309.6 KFM71840.1 - 0.014 15.5 0.1 0.053 13.6 0.1 2.0 2 0 0 2 2 2 0 HTH domain HTH_23 PF13384.6 KFM71840.1 - 0.015 15.1 8.8 0.044 13.6 0.3 2.8 3 0 0 3 3 3 0 Homeodomain-like domain TrmB PF01978.19 KFM71840.1 - 0.018 14.9 0.1 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 KFM71840.1 - 0.025 14.6 2.3 1.3 9.1 0.2 2.4 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM71840.1 - 0.03 14.4 0.6 0.065 13.3 0.2 1.8 2 0 0 2 2 1 0 Helix-turn-helix domain of resolvase HTH_33 PF13592.6 KFM71840.1 - 0.034 13.8 0.1 0.086 12.5 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.6 KFM71840.1 - 0.28 10.8 1.0 14 5.4 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 KFM71840.1 - 0.71 10.0 2.0 5.1 7.2 0.1 2.5 2 1 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.6 KFM71840.1 - 2.3 8.0 6.9 0.87 9.4 0.2 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM71840.1 - 5.5 7.0 6.1 0.97 9.5 0.2 2.5 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain EGF_2 PF07974.13 KFM71841.1 - 0.0019 18.5 38.3 0.0026 18.1 14.6 53.9 39 12 16 55 55 55 18 EGF-like domain EGF PF00008.27 KFM71841.1 - 0.0083 16.4 7.9 0.0083 16.4 7.9 52.8 53 2 1 54 54 54 13 EGF-like domain MLANA PF14991.6 KFM71841.1 - 0.036 14.3 0.3 0.11 12.8 0.3 1.8 1 0 0 1 1 1 0 Protein melan-A YoaP PF14268.6 KFM71841.1 - 0.51 9.9 2.1 31 4.2 0.1 3.6 4 0 0 4 4 4 0 YoaP-like 2-Hacid_dh PF00389.30 KFM71841.1 - 2.4 7.8 10.0 78 2.9 0.0 5.9 7 0 0 7 7 7 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain EGF PF00008.27 KFM71842.1 - 0.0048 17.2 4.2 0.0048 17.2 4.2 25.2 22 2 2 25 25 25 9 EGF-like domain Miga PF10265.9 KFM71843.1 - 3.7e-37 128.5 0.6 3.9e-37 128.5 0.6 1.0 1 0 0 1 1 1 1 Mitoguardin Miga PF10265.9 KFM71844.1 - 1.5e-28 100.1 0.1 1.7e-28 99.9 0.1 1.0 1 0 0 1 1 1 1 Mitoguardin Miga PF10265.9 KFM71845.1 - 1.4e-09 37.5 0.2 4.6e-09 35.8 0.2 1.7 1 1 0 1 1 1 1 Mitoguardin MFS_1 PF07690.16 KFM71846.1 - 1e-41 143.1 24.9 1e-41 143.1 24.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KFM71846.1 - 4.4e-16 58.3 19.5 5.4e-06 25.0 0.1 4.3 1 1 2 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KFM71846.1 - 6.6e-12 45.0 6.1 6.6e-12 45.0 6.1 2.2 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 KFM71846.1 - 4.1e-07 28.9 18.4 0.00016 20.4 9.9 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein DUF4190 PF13828.6 KFM71846.1 - 0.043 13.6 1.1 0.29 10.9 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Mntp PF02659.15 KFM71846.1 - 0.44 10.3 6.8 0.86 9.3 0.2 3.0 2 1 1 3 3 3 0 Putative manganese efflux pump Amastin PF07344.11 KFM71846.1 - 1.2 9.0 12.8 0.3 10.9 7.1 2.5 2 0 0 2 2 2 0 Amastin surface glycoprotein DNApol_Exo PF18136.1 KFM71847.1 - 0.0073 15.5 0.5 0.0089 15.2 0.5 1.1 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain Metallopep PF12044.8 KFM71847.1 - 0.11 11.1 0.3 0.14 10.7 0.3 1.1 1 0 0 1 1 1 0 Putative peptidase family CREPT PF16566.5 KFM71848.1 - 0.045 13.9 3.2 0.067 13.4 3.2 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour FlgN PF05130.12 KFM71848.1 - 0.092 13.3 1.7 6.5 7.3 0.3 2.2 2 0 0 2 2 2 0 FlgN protein YscO-like PF16789.5 KFM71848.1 - 0.11 12.5 5.8 0.17 11.9 5.7 1.3 1 1 0 1 1 1 0 YscO-like protein DUF16 PF01519.16 KFM71848.1 - 1.4 9.5 7.9 2.9 8.4 7.9 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Acyltransferase PF01553.21 KFM71849.1 - 9.3e-32 109.5 0.1 1.3e-31 109.0 0.1 1.2 1 0 0 1 1 1 1 Acyltransferase MDM1 PF15501.6 KFM71850.1 - 1.7e-20 73.7 14.9 2.9e-20 72.9 14.9 1.4 1 0 0 1 1 1 1 Nuclear protein MDM1 NAP PF00956.18 KFM71851.1 - 2.7e-31 108.7 12.1 2e-28 99.3 3.6 3.1 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 KFM71851.1 - 0.0063 16.4 4.0 0.011 15.6 2.5 2.1 2 0 0 2 2 2 1 Bacteriophage Mu Gam like protein Cytochrom_B562 PF07361.11 KFM71851.1 - 0.011 16.4 1.6 0.011 16.4 1.6 2.6 3 0 0 3 3 3 0 Cytochrome b562 KaiA PF07688.12 KFM71851.1 - 0.013 15.6 0.4 0.022 14.9 0.4 1.3 1 0 0 1 1 1 0 KaiA C-terminal domain DUF98 PF01947.16 KFM71851.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase DUF4407 PF14362.6 KFM71851.1 - 0.47 9.7 2.2 0.23 10.8 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Allantoicase PF03561.15 KFM71852.1 - 1.7 8.6 5.2 9.7 6.2 0.0 4.6 2 1 2 4 4 4 0 Allantoicase repeat L_HMGIC_fpl PF10242.9 KFM71853.1 - 4.2e-57 193.3 11.0 5e-57 193.0 11.0 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 KFM71853.1 - 2.7e-07 30.5 15.9 2.4e-06 27.4 15.8 2.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Atthog PF18800.1 KFM71853.1 - 0.00013 21.8 3.2 0.00027 20.9 3.2 1.5 1 0 0 1 1 1 1 Attenuator of Hedgehog PMP22_Claudin PF00822.20 KFM71853.1 - 0.004 17.0 8.5 0.0063 16.4 8.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family HTH_Tnp_Tc3_2 PF01498.18 KFM71854.1 - 2e-16 60.0 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71854.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5641 PF18701.1 KFM71855.1 - 3.7e-22 78.3 0.6 4.1e-22 78.1 0.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DDE_1 PF03184.19 KFM71856.1 - 3.9e-50 169.9 0.1 7.1e-50 169.1 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM71856.1 - 1.8e-12 47.1 0.0 1.5e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM71856.1 - 0.00088 18.9 0.0 0.003 17.1 0.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MyTH4 PF00784.17 KFM71858.1 - 1.4e-32 112.4 0.1 1.3e-31 109.2 0.0 2.8 2 0 0 2 2 2 1 MyTH4 domain SH3_9 PF14604.6 KFM71858.1 - 3.9e-09 36.2 0.0 9.2e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM71858.1 - 6.6e-09 35.3 0.0 1.6e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM71858.1 - 9e-07 28.4 0.0 1.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain FERM_M PF00373.18 KFM71858.1 - 1.7e-05 25.2 0.0 1.7e-05 25.2 0.0 4.1 5 0 0 5 5 5 1 FERM central domain IQ PF00612.27 KFM71859.1 - 9.9e-10 37.4 11.0 2.5e-06 26.8 1.6 2.3 2 0 0 2 2 2 2 IQ calmodulin-binding motif Myosin_head PF00063.21 KFM71859.1 - 0.029 12.6 0.0 0.054 11.7 0.0 1.4 2 0 0 2 2 2 0 Myosin head (motor domain) HTH_17 PF12728.7 KFM71859.1 - 0.1 12.8 1.5 11 6.3 0.5 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain Myosin_head PF00063.21 KFM71860.1 - 1.6e-20 72.9 0.0 1.7e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 KFM71860.1 - 0.063 13.5 0.0 0.088 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM71860.1 - 0.065 13.6 0.1 0.072 13.5 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFM71860.1 - 0.096 12.6 0.1 0.096 12.6 0.1 1.1 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 KFM71860.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Myosin_head PF00063.21 KFM71861.1 - 0.0054 15.0 0.1 0.0062 14.8 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CH PF00307.31 KFM71862.1 - 8.5e-08 32.3 0.0 9.8e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM71862.1 - 2.5e-05 24.0 0.0 3e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 CAMSAP CH domain PPR_long PF17177.4 KFM71863.1 - 8e-14 51.5 0.4 1.5e-06 27.8 0.0 3.8 3 1 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KFM71863.1 - 7.9e-13 48.4 10.6 5.4e-05 23.3 0.0 7.8 6 1 4 10 10 10 3 PPR repeat family PPR_3 PF13812.6 KFM71863.1 - 2e-11 43.8 9.4 8.9e-07 28.9 0.1 6.6 7 1 1 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.20 KFM71863.1 - 2.9e-09 36.6 22.2 0.049 13.9 0.4 9.8 11 0 0 11 11 11 3 PPR repeat PPR_1 PF12854.7 KFM71863.1 - 5.2e-09 35.6 1.1 0.002 17.8 0.0 6.2 6 0 0 6 6 6 2 PPR repeat TPR_8 PF13181.6 KFM71863.1 - 0.029 14.6 0.7 61 4.2 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Clathrin PF00637.20 KFM71863.1 - 2.3 8.1 10.3 39 4.1 0.0 5.4 3 2 3 6 6 6 0 Region in Clathrin and VPS COesterase PF00135.28 KFM71865.1 - 7.1e-129 431.0 0.0 8e-129 430.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM71865.1 - 1.9e-10 41.0 0.6 5.2e-10 39.5 0.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM71865.1 - 0.089 12.3 0.4 0.2 11.1 0.4 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DDE_3 PF13358.6 KFM71866.1 - 3.3e-10 39.9 0.0 5.1e-09 36.0 0.0 2.5 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71866.1 - 2.6e-09 37.2 3.9 5.5e-09 36.2 3.9 1.6 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.6 KFM71866.1 - 0.017 14.7 0.2 0.041 13.5 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_12 PF08461.10 KFM71866.1 - 0.034 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DDE_3 PF13358.6 KFM71867.1 - 1e-10 41.6 0.0 1.1e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM71868.1 - 7.6e-16 58.2 0.1 7.4e-15 55.0 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71868.1 - 9.1e-16 57.9 6.5 1.7e-15 57.0 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71868.1 - 0.00086 19.9 1.5 0.00086 19.9 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71868.1 - 0.0034 17.1 0.1 0.14 12.0 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71868.1 - 0.019 15.1 0.1 0.076 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71868.1 - 0.041 13.9 0.4 0.041 13.9 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM71869.1 - 4.9e-16 58.7 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71869.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71869.1 - 2.2e-07 30.5 1.2 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71869.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71869.1 - 1.8 9.2 15.0 0.12 13.0 1.8 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Fz PF01392.22 KFM71870.1 - 6.8e-29 100.7 1.5 9.3e-29 100.3 1.5 1.2 1 0 0 1 1 1 1 Fz domain T-box PF00907.22 KFM71871.1 - 7.5e-37 127.4 1.8 8.4e-37 127.2 1.8 1.0 1 0 0 1 1 1 1 T-box zf-H2C2_2 PF13465.6 KFM71873.1 - 7.6e-90 291.7 116.7 2.7e-07 30.7 2.6 15.1 15 0 0 15 15 15 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM71873.1 - 8.1e-70 227.6 122.9 1.7e-06 28.1 1.7 14.1 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM71873.1 - 1.5e-48 159.2 120.8 0.00053 20.6 0.4 14.1 14 0 0 14 14 14 14 C2H2-type zinc finger zf-met PF12874.7 KFM71873.1 - 1e-39 133.8 115.4 0.00073 19.8 2.7 14.7 13 1 1 14 14 14 14 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM71873.1 - 2.3e-24 84.8 108.3 0.01 15.8 1.6 14.6 14 0 0 14 14 14 12 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM71873.1 - 3.8e-17 61.7 85.1 0.002 17.8 0.2 13.2 13 0 0 13 13 13 10 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM71873.1 - 2.7e-15 56.2 94.6 0.056 13.7 1.1 15.7 14 3 1 15 15 15 9 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM71873.1 - 3.5e-06 26.7 77.4 0.018 14.8 0.3 13.7 14 0 0 14 14 14 5 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM71873.1 - 7.8e-05 22.6 51.5 0.045 13.8 1.0 12.6 8 3 6 14 14 14 2 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM71873.1 - 8.9e-05 22.5 51.9 9.7 6.4 0.3 12.7 13 0 0 13 13 13 0 DBF zinc finger ADK_lid PF05191.14 KFM71873.1 - 0.00056 19.8 59.6 0.13 12.3 1.1 8.7 5 3 2 7 7 7 3 Adenylate kinase, active site lid Mga PF05043.13 KFM71873.1 - 0.0015 19.0 10.7 0.15 12.7 0.2 5.5 5 2 1 6 6 5 1 Mga helix-turn-helix domain C1_1 PF00130.22 KFM71873.1 - 0.0015 18.3 90.9 2.1 8.3 0.9 13.0 5 3 7 12 12 12 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 KFM71873.1 - 0.002 18.0 63.2 2.7 8.0 0.1 14.1 14 0 0 14 14 14 1 zinc-finger of a C2HC-type PqqA PF08042.11 KFM71873.1 - 0.0023 17.9 10.2 98 3.2 0.0 8.8 11 0 0 11 11 11 0 PqqA family BolA PF01722.18 KFM71873.1 - 0.0099 16.1 22.3 0.44 10.9 0.1 7.4 1 1 6 7 7 7 1 BolA-like protein zf-RRPl_C4 PF17026.5 KFM71873.1 - 0.02 15.0 68.6 1.1 9.4 2.6 5.9 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type ATP-grasp_4 PF13535.6 KFM71873.1 - 0.028 14.0 0.6 9.5 5.8 0.0 4.4 2 2 2 5 5 5 0 ATP-grasp domain FYVE PF01363.21 KFM71873.1 - 0.037 14.2 77.3 0.84 9.8 8.7 7.2 1 1 4 6 6 6 0 FYVE zinc finger Complex1_49kDa PF00346.19 KFM71873.1 - 0.038 13.1 6.3 3.2 6.8 0.1 3.5 1 1 1 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF2256 PF10013.9 KFM71873.1 - 0.13 12.4 69.5 1.5 9.0 0.3 13.8 14 0 0 14 14 14 0 Uncharacterized protein conserved in bacteria (DUF2256) UvsY PF11056.8 KFM71873.1 - 0.14 12.5 1.7 3.6 8.0 0.0 3.5 3 2 1 4 4 4 0 Recombination, repair and ssDNA binding protein UvsY GAGA PF09237.11 KFM71873.1 - 0.15 11.9 29.1 7.3 6.5 0.1 9.1 4 4 6 10 10 10 0 GAGA factor zf-CHCC PF10276.9 KFM71873.1 - 0.41 10.7 31.7 32 4.7 0.1 11.5 14 0 0 14 14 14 0 Zinc-finger domain FAM110_N PF14161.6 KFM71873.1 - 0.43 10.8 4.4 18 5.6 0.0 4.7 2 2 4 7 7 7 0 Centrosome-associated N terminus zf-C2H2_9 PF16293.5 KFM71873.1 - 2.2 8.2 69.5 3.5 7.5 0.2 13.5 2 2 12 14 14 14 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 KFM71873.1 - 5.6 7.2 53.0 0.55 10.4 1.0 8.8 4 3 7 11 11 11 0 Zinc ribbon domain TRAF6_Z2 PF18048.1 KFM71873.1 - 6.2 7.0 61.4 6.2 7.0 0.5 13.1 14 0 0 14 14 14 0 TNF receptor-associated factor 6 zinc finger 2 SH2 PF00017.24 KFM71874.1 - 2.7e-24 85.1 0.0 3e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 KFM71874.1 - 0.048 13.0 0.0 0.078 12.4 0.0 1.3 1 1 0 1 1 1 0 SH2 domain HTH_Tnp_Tc3_2 PF01498.18 KFM71875.1 - 8.3e-16 58.0 6.5 1.5e-15 57.2 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71875.1 - 1.2e-15 57.6 0.1 1.3e-14 54.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM71875.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71875.1 - 0.0024 17.6 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM71875.1 - 0.015 15.4 0.1 0.066 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM71875.1 - 0.035 14.1 2.6 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix BTB PF00651.31 KFM71876.1 - 8.1e-25 87.2 0.1 1.2e-24 86.6 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain RFX5_DNA_bdg PF14621.6 KFM71876.1 - 0.0027 17.5 3.0 0.0045 16.8 3.0 1.3 1 0 0 1 1 1 1 RFX5 DNA-binding domain AT_hook PF02178.19 KFM71876.1 - 0.2 11.7 6.5 0.38 10.8 6.5 1.5 1 0 0 1 1 1 0 AT hook motif zf-C2H2_4 PF13894.6 KFM71877.1 - 2.7e-05 24.7 2.4 0.043 14.7 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KFM71877.1 - 0.00016 21.9 3.7 0.17 12.2 0.5 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KFM71877.1 - 0.0024 17.5 0.7 0.067 12.8 0.1 2.2 2 0 0 2 2 2 1 MYST family zinc finger domain zf-C2H2 PF00096.26 KFM71877.1 - 0.0043 17.4 3.7 0.069 13.6 0.6 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type GAGA PF09237.11 KFM71877.1 - 0.0084 15.9 0.1 2.3 8.1 0.0 2.6 2 1 0 2 2 2 1 GAGA factor zf-C2H2_2 PF12756.7 KFM71877.1 - 0.013 15.8 1.5 3 8.2 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFM71877.1 - 0.014 15.7 2.3 2.4 8.5 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF4451 PF14616.6 KFM71877.1 - 0.031 14.5 2.1 0.12 12.6 2.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) zf-BED PF02892.15 KFM71877.1 - 0.035 14.1 2.7 4.9 7.3 0.3 2.4 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KFM71877.1 - 0.56 10.7 5.3 10 6.8 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Exo_endo_phos_2 PF14529.6 KFM71878.1 - 8.9e-15 54.6 0.7 2.3e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KFM71878.1 - 2.6e-10 40.2 0.1 2.2e-08 33.9 0.0 2.9 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 KFM71878.1 - 0.0051 16.4 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family VATC PF18716.1 KFM71879.1 - 0.059 13.2 3.4 1.4 8.8 0.6 2.3 2 0 0 2 2 2 0 Vms1-associating treble clef domain Multi-haem_cyto PF13447.6 KFM71879.1 - 0.062 12.5 3.2 0.073 12.3 3.2 1.1 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH PADR1 PF08063.12 KFM71879.1 - 0.14 11.9 4.1 0.25 11.2 4.1 1.4 1 0 0 1 1 1 0 PADR1 (NUC008) domain Vps39_2 PF10367.9 KFM71879.1 - 0.18 12.3 3.7 0.31 11.5 0.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-Di19 PF05605.12 KFM71879.1 - 0.32 11.3 8.2 0.23 11.8 5.9 1.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFM71879.1 - 0.58 10.2 0.3 0.58 10.2 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM71879.1 - 1.4 9.5 9.3 9.5 6.8 1.5 2.9 2 1 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 KFM71879.1 - 4.1 7.6 7.6 6.1 7.0 0.9 2.6 2 1 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.21 KFM71879.1 - 4.3 7.6 11.3 5.6 7.2 9.2 2.1 2 1 0 2 2 2 0 FYVE zinc finger zf-C2H2_4 PF13894.6 KFM71879.1 - 6.2 7.9 11.6 12 7.0 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger RVT_1 PF00078.27 KFM71881.1 - 3.9e-54 183.5 0.3 6.6e-54 182.8 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 KFM71882.1 - 4.4e-16 58.9 0.1 5.4e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71882.1 - 7.3e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM71882.1 - 0.00067 20.2 1.5 0.00067 20.2 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM71882.1 - 0.0018 18.0 0.0 0.082 12.7 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM71882.1 - 0.023 14.7 2.4 0.028 14.4 0.3 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM71882.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Nup192 PF11894.8 KFM71883.1 - 1.4e-282 940.8 0.6 1.7e-282 940.5 0.6 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 HTH_32 PF13565.6 KFM71884.1 - 7.7e-05 23.2 1.5 0.00095 19.7 0.0 2.4 1 1 1 2 2 2 1 Homeodomain-like domain DUF3453 PF11935.8 KFM71884.1 - 0.026 14.2 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) HTH_Tnp_Tc3_2 PF01498.18 KFM71884.1 - 0.084 13.1 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 Transposase LIF_OSM PF01291.17 KFM71884.1 - 0.096 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 LIF / OSM family HTH_24 PF13412.6 KFM71884.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 KFM71884.1 - 0.37 10.8 1.8 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn helix bZIP_2 PF07716.15 KFM71885.1 - 2.9e-16 59.3 15.2 5.6e-16 58.4 11.3 2.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM71885.1 - 8.4e-07 29.0 12.0 9.8e-05 22.4 7.6 2.5 2 0 0 2 2 2 2 bZIP transcription factor Mto2_bdg PF12808.7 KFM71885.1 - 0.36 11.2 10.4 0.59 10.5 4.7 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HTH_Tnp_Tc3_2 PF01498.18 KFM71886.1 - 4.2e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71886.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71886.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71886.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71886.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71887.1 - 5.1e-16 58.7 3.5 6.1e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71887.1 - 1.4e-13 50.8 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71887.1 - 2.3e-07 30.5 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71887.1 - 0.0028 17.4 0.6 0.008 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71887.1 - 2.4 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain MIF4G PF02854.19 KFM71888.1 - 3.7e-41 141.1 7.9 3.7e-41 141.1 7.9 2.2 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.17 KFM71888.1 - 2.8e-06 27.3 1.4 1.2e-05 25.2 0.6 2.4 2 0 0 2 2 2 1 MA3 domain HD_2 PF12917.7 KFM71888.1 - 0.053 13.3 0.3 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme EutA PF06277.11 KFM71888.1 - 0.056 12.3 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA PaREP1 PF05942.11 KFM71888.1 - 0.088 12.7 0.0 0.36 10.8 0.0 2.0 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family FANCI_S2 PF14676.6 KFM71888.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.7 3 1 0 3 3 3 0 FANCI solenoid 2 Tai4 PF16695.5 KFM71888.1 - 0.15 12.6 1.0 32 5.1 0.1 3.2 3 0 0 3 3 3 0 Type VI secretion system (T6SS), amidase immunity protein HTH_29 PF13551.6 KFM71889.1 - 1.6e-07 31.2 0.2 1.6e-07 31.2 0.2 1.4 2 0 0 2 2 2 1 Winged helix-turn helix PAX PF00292.18 KFM71889.1 - 0.00011 22.1 0.1 0.00013 21.9 0.1 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFM71889.1 - 0.00016 21.3 0.2 0.00022 20.9 0.2 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM71889.1 - 0.00041 20.3 0.0 0.0005 20.0 0.0 1.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM71889.1 - 0.00069 19.7 0.5 0.00069 19.7 0.5 1.4 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KFM71889.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_31 PF13560.6 KFM71889.1 - 0.01 16.2 0.4 0.015 15.6 0.2 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 KFM71889.1 - 0.023 14.5 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_38 PF13936.6 KFM71889.1 - 0.025 14.3 0.1 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.16 KFM71889.1 - 0.054 13.3 0.1 0.12 12.2 0.0 1.6 1 1 1 2 2 2 0 helix-turn-helix, Psq domain HTH_7 PF02796.15 KFM71889.1 - 0.058 13.5 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Ribosomal_S19e PF01090.19 KFM71889.1 - 0.06 13.0 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S19e DUF4817 PF16087.5 KFM71889.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) MarR PF01047.22 KFM71889.1 - 0.096 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 MarR family CENP-B_N PF04218.13 KFM71889.1 - 0.2 11.3 0.2 0.32 10.7 0.1 1.4 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Coprogen_oxidas PF01218.18 KFM71890.1 - 8.5e-138 458.0 0.2 1.1e-137 457.6 0.2 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF1758 PF05585.12 KFM71892.1 - 2.8e-17 63.0 0.1 7.1e-17 61.7 0.1 1.7 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 KFM71892.1 - 0.025 15.2 0.0 0.052 14.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_5 PF14787.6 KFM71892.1 - 0.69 9.7 7.0 2.6 7.8 0.7 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Lectin_C PF00059.21 KFM71894.1 - 3.3e-05 24.6 0.1 4e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Lectin C-type domain ComX PF05952.12 KFM71894.1 - 0.017 15.1 0.1 0.081 12.9 0.1 1.9 1 1 1 2 2 2 0 Bacillus competence pheromone ComX DUF2625 PF10946.8 KFM71894.1 - 0.071 12.2 0.0 0.084 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF2625 CUB PF00431.20 KFM71895.1 - 1.7e-23 83.0 0.0 1.6e-14 54.1 0.0 2.0 2 0 0 2 2 2 2 CUB domain OAD_gamma PF04277.13 KFM71896.1 - 0.023 15.3 0.0 0.035 14.7 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Syndecan PF01034.20 KFM71896.1 - 0.36 10.8 1.6 0.6 10.1 1.6 1.3 1 0 0 1 1 1 0 Syndecan domain PDEase_I PF00233.19 KFM71898.1 - 1.1e-92 310.1 3.4 1.4e-92 309.8 3.4 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TIR PF01582.20 KFM71900.1 - 1.6e-23 83.4 0.6 2.4e-23 82.8 0.6 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 KFM71900.1 - 2.4e-19 68.8 28.5 1.2e-10 41.0 8.3 4.6 3 1 1 4 4 4 4 Leucine rich repeat TIR_2 PF13676.6 KFM71900.1 - 6.2e-16 59.1 0.2 1.1e-15 58.3 0.2 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 KFM71900.1 - 2.7e-07 30.8 36.3 0.021 15.2 3.7 6.1 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM71900.1 - 3.6e-07 30.2 1.0 1.7e-06 28.0 0.4 2.2 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM71900.1 - 0.00077 19.0 5.7 0.0014 18.2 4.2 2.1 1 1 0 1 1 1 1 Leucine-rich repeat Conotoxin PF02950.17 KFM71902.1 - 0.0014 19.6 1.6 0.018 16.0 0.0 2.6 2 0 0 2 2 2 1 Conotoxin Presenilin PF01080.17 KFM71902.1 - 2.2 7.0 4.9 2.8 6.6 4.9 1.1 1 0 0 1 1 1 0 Presenilin Trefoil PF00088.18 KFM71903.1 - 3.4e-07 30.0 6.4 3.4e-07 30.0 6.4 2.2 2 0 0 2 2 2 1 Trefoil (P-type) domain COesterase PF00135.28 KFM71904.1 - 0.0001 21.3 0.9 0.00012 21.1 0.9 1.1 1 0 0 1 1 1 1 Carboxylesterase family DnaJ PF00226.31 KFM71905.1 - 9.3e-21 73.7 0.2 2.4e-20 72.4 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain EMC3_TMCO1 PF01956.16 KFM71905.1 - 0.1 12.3 0.2 0.2 11.4 0.0 1.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF4140 PF13600.6 KFM71907.1 - 1.2 9.7 6.7 0.27 11.7 0.2 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DM4_12 PF07841.13 KFM71909.1 - 1.1e-05 26.0 0.0 2.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 DM4/DM12 family DDE_3 PF13358.6 KFM71910.1 - 2.4e-16 59.8 0.1 3.2e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71910.1 - 1.1e-10 41.5 1.0 2.8e-10 40.3 1.0 1.7 1 0 0 1 1 1 1 Transposase Homeodomain PF00046.29 KFM71912.1 - 8.2e-22 76.8 2.8 1.2e-21 76.3 2.8 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM71912.1 - 0.02 14.8 0.1 0.041 13.8 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 KFM71912.1 - 0.16 11.5 1.2 0.21 11.1 0.1 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Aldedh PF00171.22 KFM71913.1 - 1.4e-183 610.7 0.0 1.6e-183 610.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 3HCDH PF00725.22 KFM71913.1 - 0.036 14.7 0.0 15 6.3 0.0 3.6 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM71914.1 - 4.2e-16 58.9 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71914.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71914.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71914.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71914.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM71915.1 - 2.7e-16 59.6 2.2 5e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71915.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RhoGAP PF00620.27 KFM71917.1 - 2.6e-18 66.3 0.1 3.3e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 KFM71918.1 - 0.049 13.8 0.1 0.064 13.4 0.1 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Sulfotransfer_1 PF00685.27 KFM71918.1 - 0.055 12.9 0.1 0.06 12.8 0.1 1.0 1 0 0 1 1 1 0 Sulfotransferase domain DUF3128 PF11326.8 KFM71920.1 - 8e-15 55.0 5.6 1.2e-14 54.4 5.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Aminoglyc_resit PF10706.9 KFM71920.1 - 0.035 13.9 0.2 0.045 13.5 0.2 1.3 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase UCR_hinge PF02320.16 KFM71920.1 - 2.7 8.3 5.3 19 5.5 2.6 2.7 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DDE_3 PF13358.6 KFM71924.1 - 2.5e-11 43.5 0.0 3.3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM71926.1 - 3e-16 59.5 0.1 3.4e-15 56.1 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM71926.1 - 1.2e-10 41.4 1.0 2.9e-10 40.3 1.0 1.7 1 0 0 1 1 1 1 Transposase Fibrinogen_C PF00147.18 KFM71927.1 - 4.7e-60 203.1 3.2 7.6e-60 202.5 3.2 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Med14 PF08638.11 KFM71927.1 - 0.017 14.5 1.0 0.043 13.2 0.7 1.8 1 1 0 1 1 1 0 Mediator complex subunit MED14 Imm63 PF15599.6 KFM71927.1 - 1.6 9.2 6.2 4.9 7.6 3.9 2.9 2 1 0 2 2 2 0 Immunity protein 63 WD40 PF00400.32 KFM71928.1 - 0.019 15.8 0.2 0.056 14.3 0.0 1.9 2 0 0 2 2 2 0 WD domain, G-beta repeat LVIVD PF08309.11 KFM71928.1 - 0.11 11.8 0.3 0.2 11.0 0.3 1.5 1 0 0 1 1 1 0 LVIVD repeat SH3_1 PF00018.28 KFM71929.1 - 8.7e-13 47.7 0.1 1.5e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM71929.1 - 1.7e-11 43.8 0.0 2.5e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM71929.1 - 4.7e-10 39.0 0.0 8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Shikimate_dh_N PF08501.11 KFM71929.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain RhoGEF PF00621.20 KFM71930.1 - 3.1e-47 161.2 5.8 5.5e-47 160.4 4.6 2.0 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 KFM71930.1 - 1.4e-16 60.6 0.2 3.6e-16 59.3 0.2 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM71930.1 - 1.8e-15 56.5 0.3 4.6e-15 55.2 0.3 1.7 1 0 0 1 1 1 1 CAMSAP CH domain C1_1 PF00130.22 KFM71930.1 - 1.2e-12 47.6 2.5 2.8e-12 46.3 2.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFM71930.1 - 7.6e-11 42.5 0.9 2.6e-10 40.7 0.9 2.0 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 KFM71930.1 - 9.7e-07 28.4 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM71930.1 - 2.6e-05 23.7 0.0 5.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH_10 PF15411.6 KFM71930.1 - 2.7e-05 24.4 3.2 0.00017 21.8 0.1 2.6 1 1 1 2 2 2 1 Pleckstrin homology domain SH3_9 PF14604.6 KFM71930.1 - 0.0011 18.8 0.0 0.0032 17.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain IQ_SEC7_PH PF16453.5 KFM71930.1 - 0.0039 17.2 0.1 0.012 15.6 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 KFM71930.1 - 0.0044 16.8 3.0 0.022 14.6 3.0 2.1 1 1 0 1 1 1 1 PH domain PH_5 PF15405.6 KFM71930.1 - 0.0055 16.8 4.6 0.062 13.4 0.5 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain C1_2 PF03107.16 KFM71930.1 - 0.012 15.9 5.1 0.012 15.9 3.0 2.1 2 0 0 2 2 2 0 C1 domain CDC24 PF06395.11 KFM71930.1 - 0.017 15.4 0.3 0.056 13.7 0.3 1.9 1 0 0 1 1 1 0 CDC24 Calponin zf-RING-like PF08746.11 KFM71930.1 - 0.094 13.0 4.5 0.5 10.7 4.5 2.3 1 0 0 1 1 1 0 RING-like domain Zf_RING PF16744.5 KFM71930.1 - 0.14 12.3 1.2 0.54 10.4 1.2 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger PHD_2 PF13831.6 KFM71930.1 - 0.15 11.7 2.7 0.44 10.1 2.7 1.8 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 KFM71930.1 - 0.21 11.6 2.6 0.58 10.1 2.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_3 PF13922.6 KFM71930.1 - 8.1 6.9 6.2 1.3 9.4 1.4 2.3 2 0 0 2 2 1 0 PHD domain of transcriptional enhancer, Asx DSPc PF00782.20 KFM71931.1 - 1.4e-08 34.7 0.0 1.6e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFM71931.1 - 0.0069 16.5 0.0 0.0088 16.2 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFM71931.1 - 0.054 13.1 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HTH_48 PF17906.1 KFM71932.1 - 2.7e-10 40.2 0.7 7.4e-10 38.8 0.7 1.7 1 1 0 1 1 1 1 HTH domain in Mos1 transposase ABC_tran PF00005.27 KFM71933.1 - 3.2e-45 154.0 0.0 1.6e-22 80.5 0.0 4.0 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 KFM71933.1 - 9.4e-17 61.8 11.7 4.3e-06 26.7 0.0 4.9 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFM71933.1 - 2.4e-15 57.1 1.2 0.00045 20.0 0.0 3.8 2 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 KFM71933.1 - 9.9e-09 35.6 0.5 0.0064 16.8 0.2 3.3 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 KFM71933.1 - 1.6e-08 34.3 16.6 0.00056 19.4 0.0 4.9 3 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KFM71933.1 - 7.1e-07 29.5 2.1 0.0039 17.3 0.0 3.7 3 2 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KFM71933.1 - 2.5e-06 28.0 4.0 0.021 15.3 0.2 4.4 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 KFM71933.1 - 2.7e-06 27.8 0.5 0.096 13.1 0.0 3.3 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFM71933.1 - 3.2e-06 27.2 0.0 0.076 12.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KFM71933.1 - 4.9e-06 27.0 0.4 0.016 15.6 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KFM71933.1 - 5.7e-06 26.0 2.1 0.0076 16.0 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KFM71933.1 - 1.2e-05 25.1 0.5 0.055 13.2 0.1 3.3 2 2 1 3 3 3 2 AAA domain AAA_24 PF13479.6 KFM71933.1 - 1.2e-05 25.1 2.4 0.09 12.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KFM71933.1 - 1.6e-05 24.9 0.8 0.3 11.1 0.0 3.8 5 0 0 5 5 3 2 AAA domain AAA_23 PF13476.6 KFM71933.1 - 1.8e-05 25.3 0.2 0.0006 20.4 0.0 5.0 3 2 1 4 4 2 2 AAA domain AAA_28 PF13521.6 KFM71933.1 - 1.9e-05 25.0 0.0 0.23 11.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFM71933.1 - 2e-05 24.9 0.1 0.38 11.2 0.0 3.7 3 0 0 3 3 3 2 RNA helicase AAA_5 PF07728.14 KFM71933.1 - 5.3e-05 23.2 1.5 0.26 11.3 0.1 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KFM71933.1 - 0.00012 22.1 0.2 0.091 12.8 0.2 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 KFM71933.1 - 0.00015 21.7 16.6 0.00015 21.7 16.6 4.2 4 1 0 4 4 2 1 ABC transporter cobW PF02492.19 KFM71933.1 - 0.0003 20.4 0.1 0.17 11.4 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KFM71933.1 - 0.00046 19.4 0.0 0.45 9.7 0.0 3.0 2 0 0 2 2 2 1 NB-ARC domain SRP54 PF00448.22 KFM71933.1 - 0.00059 19.5 0.9 1.4 8.5 0.0 3.0 3 0 0 3 3 2 2 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KFM71933.1 - 0.00099 19.1 5.6 0.4 10.6 0.0 3.5 3 1 1 4 4 3 2 RsgA GTPase NTPase_1 PF03266.15 KFM71933.1 - 0.0011 18.9 2.1 0.87 9.5 0.0 3.5 3 1 0 3 3 3 1 NTPase AAA_7 PF12775.7 KFM71933.1 - 0.0012 18.4 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KFM71933.1 - 0.0013 18.4 0.0 0.51 9.9 0.1 3.1 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 KFM71933.1 - 0.002 18.1 0.0 3.3 7.7 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KFM71933.1 - 0.014 15.6 5.2 2.7 8.2 0.0 3.5 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KFM71933.1 - 0.023 14.5 0.0 2.9 7.6 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KFM71933.1 - 0.035 14.4 5.0 4.7 7.5 0.1 3.7 3 1 0 3 3 3 0 AAA domain CLP1_P PF16575.5 KFM71933.1 - 0.062 13.1 1.8 12 5.7 0.0 3.8 4 0 0 4 4 4 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RuvB_N PF05496.12 KFM71933.1 - 0.072 12.8 0.4 8.6 6.1 0.0 2.7 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KFM71933.1 - 0.074 12.8 0.1 13 5.4 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 KFM71933.1 - 0.077 12.6 0.0 0.77 9.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 KFM71933.1 - 0.1 12.9 0.5 3.2 8.1 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KFM71933.1 - 0.22 11.6 0.0 0.22 11.6 0.0 4.7 3 1 2 5 5 4 0 Helicase HerA, central domain ATPase_2 PF01637.18 KFM71933.1 - 0.51 10.2 0.0 0.51 10.2 0.0 4.2 4 1 0 4 4 3 0 ATPase domain predominantly from Archaea MobB PF03205.14 KFM71933.1 - 0.65 9.9 7.0 2.4 8.1 0.0 3.3 4 0 0 4 4 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 KFM71933.1 - 1.2 8.9 6.2 3.4 7.4 0.0 3.9 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein DUF572 PF04502.13 KFM71934.1 - 5.2e-76 256.4 3.6 5.6e-76 256.3 3.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) ZZ PF00569.17 KFM71934.1 - 0.15 11.9 1.1 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type Glyco_transf_7C PF02709.14 KFM71936.1 - 6.9e-06 25.6 0.7 1.2e-05 24.9 0.7 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Ricin_B_lectin PF00652.22 KFM71936.1 - 0.00044 20.5 0.1 0.00068 19.9 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KFM71936.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain HLH PF00010.26 KFM71937.1 - 9.4e-07 28.7 3.1 2.7e-06 27.3 3.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain XPG_I_2 PF12813.7 KFM71939.1 - 2.4e-09 37.0 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 KFM71939.1 - 2.6e-07 31.1 0.0 3.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc_N PF02739.16 KFM71939.1 - 3e-06 27.2 0.0 9.8e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain XPG_I PF00867.18 KFM71939.1 - 0.0065 16.8 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 XPG I-region DUF3384 PF11864.8 KFM71940.1 - 1.7e-32 112.9 3.1 4.9e-32 111.5 3.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3384) DUF3384 PF11864.8 KFM71941.1 - 0.0017 17.4 0.0 0.0018 17.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Tuberin PF03542.16 KFM71942.1 - 2.1e-61 208.0 0.4 2.1e-61 208.0 0.4 1.6 2 0 0 2 2 2 1 Tuberin HEAT PF02985.22 KFM71942.1 - 0.075 13.3 0.0 0.56 10.6 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat Rap_GAP PF02145.15 KFM71943.1 - 1e-41 142.5 0.3 2.2e-41 141.4 0.3 1.6 1 0 0 1 1 1 1 Rap/ran-GAP DUF3070 PF11270.8 KFM71943.1 - 0.044 14.0 1.0 0.12 12.6 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) 5_nucleotid_C PF02872.18 KFM71944.1 - 4.6e-38 130.9 0.0 8e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KFM71944.1 - 0.00024 21.7 0.0 0.00062 20.3 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase RED_N PF07808.13 KFM71946.1 - 7.9e-73 244.9 6.4 7.9e-73 244.9 6.4 2.2 2 0 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 KFM71946.1 - 5.3e-53 178.2 2.3 5.3e-53 178.2 2.3 2.9 3 1 1 4 4 4 1 RED-like protein C-terminal region RVT_1 PF00078.27 KFM71947.1 - 3.2e-46 157.6 0.0 7.5e-46 156.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM71947.1 - 5.4e-15 55.3 0.0 2.1e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM71947.1 - 4.8e-09 36.1 0.0 8.8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RMI1_N PF08585.12 KFM71949.1 - 9.9e-17 61.4 0.3 2.2e-11 44.0 0.0 3.2 2 1 1 3 3 3 2 RecQ mediated genome instability protein TUDOR PF00567.24 KFM71949.1 - 6.7e-09 35.8 0.1 2.8e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 KFM71949.1 - 1.2e-05 24.8 0.2 1.2e-05 24.8 0.2 2.1 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) DUF1325 PF07039.11 KFM71949.1 - 0.0018 18.3 0.5 0.0046 17.0 0.1 1.8 2 0 0 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.6 KFM71949.1 - 0.0041 17.1 0.1 0.01 15.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 KFM71949.1 - 0.058 13.3 0.1 0.058 13.3 0.1 1.8 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Oberon_cc PF16312.5 KFM71949.1 - 0.067 13.1 1.4 0.14 12.1 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil region of Oberon DDE_3 PF13358.6 KFM71950.1 - 2.3e-13 50.1 0.0 5.3e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease Endonuclease_7 PF02945.15 KFM71951.1 - 5.9e-06 26.1 0.6 1.3e-05 25.0 0.6 1.6 1 0 0 1 1 1 1 Recombination endonuclease VII Hemopexin PF00045.19 KFM71952.1 - 6.6e-111 362.1 53.2 1.2e-16 60.3 1.1 9.4 9 0 0 9 9 9 8 Hemopexin Peptidase_M10 PF00413.24 KFM71952.1 - 1e-68 230.1 1.8 9.8e-56 188.0 0.2 2.8 3 0 0 3 3 3 2 Matrixin PG_binding_1 PF01471.18 KFM71952.1 - 4e-09 36.5 0.4 1.2e-08 35.0 0.4 1.9 1 1 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_4 PF13583.6 KFM71952.1 - 1.1e-06 28.5 0.3 0.0036 17.0 0.0 2.2 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFM71952.1 - 0.0001 22.0 1.1 0.36 10.4 0.0 3.3 3 0 0 3 3 3 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 KFM71952.1 - 0.00014 22.1 1.0 0.039 14.1 0.1 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12 DUF4953 PF16313.5 KFM71952.1 - 0.00014 21.2 0.7 0.048 12.9 0.1 2.3 2 0 0 2 2 2 2 Met-zincin Peptidase_M66 PF10462.9 KFM71952.1 - 0.00091 18.3 0.6 0.88 8.5 0.1 2.2 2 0 0 2 2 2 2 Peptidase M66 Reprolysin_3 PF13582.6 KFM71952.1 - 0.0019 18.7 4.3 0.12 12.9 0.7 2.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFM71952.1 - 0.0035 17.3 0.9 0.61 10.0 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KFM71952.1 - 0.0044 17.0 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M54 DUF3833 PF12915.7 KFM71952.1 - 0.0073 15.9 0.3 1.9 8.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3833) Metallopep PF12044.8 KFM71952.1 - 0.022 13.4 0.0 3.6 6.1 0.0 2.1 2 0 0 2 2 2 0 Putative peptidase family Peptidase_M43 PF05572.13 KFM71952.1 - 0.061 13.2 0.2 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Peptidase_M57 PF12388.8 KFM71952.1 - 0.089 12.4 0.8 0.72 9.4 0.1 2.2 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase DUF4430 PF14478.6 KFM71952.1 - 0.35 11.5 3.4 16 6.2 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4430) Pkinase_Tyr PF07714.17 KFM71953.1 - 9.3e-51 172.6 0.0 1.4e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SH2 PF00017.24 KFM71953.1 - 1.9e-35 120.8 0.4 2.2e-18 66.1 0.0 2.6 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.7 KFM71953.1 - 5.8e-33 113.3 2.2 3.6e-13 49.9 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Pkinase PF00069.25 KFM71953.1 - 1.8e-27 96.3 0.0 3e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 KFM71953.1 - 2.9e-20 72.4 2.2 2.5e-06 27.9 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM71953.1 - 1.8e-17 62.9 2.6 0.0026 18.1 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFM71953.1 - 1.6e-16 60.1 0.5 0.0003 21.0 0.0 4.1 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM71953.1 - 2.1e-15 55.3 0.3 0.0071 16.8 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Haspin_kinase PF12330.8 KFM71953.1 - 0.0057 15.7 0.0 0.0095 14.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain TetR_C_20 PF17925.1 KFM71953.1 - 0.05 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase_Tyr PF07714.17 KFM71954.1 - 4.1e-07 29.5 0.1 4.2e-07 29.5 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_Tnp_Tc3_2 PF01498.18 KFM71955.1 - 3.2e-16 59.3 3.3 5.6e-16 58.5 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM71955.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM71955.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM71955.1 - 0.0025 17.6 0.6 0.0075 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM71955.1 - 2.2 9.0 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain GMC_oxred_N PF00732.19 KFM71956.1 - 4.8e-15 55.7 0.0 5.3e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KFM71957.1 - 1.1e-14 54.5 0.0 1.3e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KFM71958.1 - 1.6e-07 31.0 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFM71958.1 - 0.00026 20.2 0.1 0.00032 19.9 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFM71958.1 - 0.00092 19.4 0.1 0.0015 18.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFM71958.1 - 0.0038 16.5 0.0 0.0047 16.2 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KFM71958.1 - 0.006 15.8 0.0 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFM71958.1 - 0.014 15.0 0.2 0.016 14.8 0.2 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFM71958.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KFM71958.1 - 0.13 11.0 0.1 0.22 10.3 0.1 1.3 1 1 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.16 KFM71958.1 - 0.15 11.7 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KFM71958.1 - 0.17 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM71959.1 - 1.3e-17 63.8 1.6 4.7e-16 58.8 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM71959.1 - 1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4758 PF15950.5 KFM71961.1 - 1e-11 45.3 0.7 1.1e-11 45.2 0.7 1.0 1 0 0 1 1 1 1 Putative sperm flagellar membrane protein DUF4758 PF15950.5 KFM71963.1 - 4.3e-140 460.9 383.7 1.9e-12 47.7 0.1 28.4 25 5 5 30 30 30 24 Putative sperm flagellar membrane protein CRF-BP PF05428.11 KFM71964.1 - 5.3e-05 22.2 0.0 5.6e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Corticotropin-releasing factor binding protein (CRF-BP) INTS5_C PF14838.6 KFM71965.1 - 3.1e-125 419.5 7.7 4e-125 419.1 7.7 1.1 1 0 0 1 1 1 1 Integrator complex subunit 5 C-terminus PDH PF02153.17 KFM71965.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase DUF2111 PF09884.9 KFM71966.1 - 0.15 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) INTS5_N PF14837.6 KFM71967.1 - 2.6e-67 226.5 0.5 3.9e-67 225.9 0.5 1.2 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus INTS5_C PF14838.6 KFM71967.1 - 6.7e-20 71.3 1.2 9.1e-18 64.3 0.1 2.1 2 0 0 2 2 2 2 Integrator complex subunit 5 C-terminus ETC_C1_NDUFA5 PF04716.14 KFM71968.1 - 2e-25 88.4 0.5 2.7e-25 87.9 0.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF1151 PF06625.11 KFM71969.1 - 1.5e-17 63.5 9.7 1.5e-17 63.5 9.7 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1151) CdiI_2 PF18593.1 KFM71970.1 - 0.13 13.0 0.1 0.22 12.2 0.1 1.3 1 0 0 1 1 1 0 CdiI immunity protein DDE_1 PF03184.19 KFM71972.1 - 9.1e-28 97.1 0.5 1.3e-27 96.5 0.5 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM71972.1 - 9.8e-12 44.7 0.1 2.1e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF4371 PF14291.6 KFM71973.1 - 3.6e-30 105.4 0.5 6.7e-30 104.5 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM71973.1 - 4e-09 36.1 0.0 4e-09 36.1 0.0 2.4 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM71973.1 - 0.047 12.7 7.6 0.06 12.3 0.4 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MAT1 PF06391.13 KFM71973.1 - 2.3 8.0 7.3 2.8 7.7 2.0 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Exonuc_VII_L PF02601.15 KFM71973.1 - 6.5 6.2 7.3 8.4 5.9 1.4 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit ARPC4 PF05856.12 KFM71974.1 - 3.1e-82 274.2 6.0 3.6e-82 273.9 6.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 KFM71974.1 - 0.023 14.8 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 Sm_like domain HTH_Tnp_Tc3_1 PF11427.8 KFM71974.1 - 0.041 13.7 0.2 0.095 12.6 0.2 1.5 1 0 0 1 1 1 0 Tc3 transposase Octopine_DH PF02317.17 KFM71974.1 - 0.048 13.8 0.1 0.064 13.3 0.1 1.2 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Par3_HAL_N_term PF12053.8 KFM71975.1 - 3.5e-10 40.0 0.0 4.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Cytokin_check_N PF10407.9 KFM71975.1 - 0.13 12.2 0.1 0.34 10.9 0.1 1.6 1 1 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Lyase_aromatic PF00221.19 KFM71977.1 - 8.7e-91 304.9 0.0 1e-90 304.7 0.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase 7tm_1 PF00001.21 KFM71978.1 - 6.8e-40 137.1 22.2 9.1e-40 136.6 22.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM71978.1 - 2.8e-10 40.3 28.7 5.1e-10 39.4 28.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFM71978.1 - 2e-09 37.2 23.5 2.8e-09 36.7 23.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFM71978.1 - 2.9 7.5 18.0 22 4.6 18.0 2.1 1 1 0 1 1 1 0 Olfactory receptor USP8_interact PF08941.10 KFM71979.1 - 1.2e-19 70.8 0.3 2.3e-19 69.9 0.3 1.4 1 0 0 1 1 1 1 USP8 interacting zf-C3HC4_2 PF13923.6 KFM71979.1 - 1.8e-10 40.5 7.9 1.8e-10 40.5 7.9 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM71979.1 - 6.2e-08 32.4 8.2 6.2e-08 32.4 8.2 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM71979.1 - 8.4e-08 32.4 8.1 8.4e-08 32.4 8.1 2.5 3 1 0 3 3 3 1 Ring finger domain U-box PF04564.15 KFM71979.1 - 2.1e-07 31.0 0.1 6.7e-07 29.4 0.1 1.9 2 0 0 2 2 2 1 U-box domain zf-C3HC4_3 PF13920.6 KFM71979.1 - 6.2e-07 29.2 4.7 6.2e-07 29.2 4.7 2.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFM71979.1 - 8e-07 28.8 0.7 2.6e-06 27.2 0.7 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KFM71979.1 - 1.5e-06 28.2 7.3 1.5e-06 28.2 7.3 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFM71979.1 - 1.7e-06 27.9 9.2 1.7e-06 27.9 9.2 2.4 4 0 0 4 4 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM71979.1 - 4.3e-06 26.6 6.0 1.6e-05 24.8 6.0 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFM71979.1 - 4.7e-06 26.8 8.9 4.7e-06 26.8 8.9 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KFM71979.1 - 1e-05 25.2 2.6 1e-05 25.2 2.6 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Sina PF03145.16 KFM71979.1 - 0.00031 20.8 3.0 0.00052 20.0 3.0 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-ANAPC11 PF12861.7 KFM71979.1 - 0.00037 20.5 1.8 0.00037 20.5 1.8 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KFM71979.1 - 0.0028 17.7 4.3 0.0028 17.7 4.3 2.2 2 1 0 2 2 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KFM71979.1 - 0.015 15.2 9.2 0.41 10.5 9.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Plavaka PF18759.1 KFM71979.1 - 0.042 13.1 0.2 0.065 12.5 0.2 1.2 1 0 0 1 1 1 0 Plavaka transposase zf-TRAF PF02176.18 KFM71979.1 - 0.073 13.8 2.4 0.073 13.8 2.4 3.5 2 1 1 3 3 3 0 TRAF-type zinc finger zf-RING_4 PF14570.6 KFM71979.1 - 0.18 11.6 5.9 6.1 6.7 6.7 2.8 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain TRAF6_Z2 PF18048.1 KFM71979.1 - 0.77 9.9 8.9 0.16 12.0 4.6 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-C3HC4_5 PF17121.5 KFM71979.1 - 1.2 9.1 8.0 8.7 6.3 7.8 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 KFM71979.1 - 1.3 9.3 11.3 0.26 11.5 4.1 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Sulfotransfer_1 PF00685.27 KFM71981.1 - 1.6e-59 201.6 0.4 2.2e-59 201.2 0.4 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM71981.1 - 5.6e-08 33.4 0.2 2.5e-07 31.3 0.2 1.8 1 1 1 2 2 2 1 Sulfotransferase family Caprin-1_dimer PF18293.1 KFM71982.1 - 0.033 14.7 0.7 10 6.6 0.1 2.3 2 0 0 2 2 2 0 Caprin-1 dimerization domain RNase_H PF00075.24 KFM71983.1 - 3.5e-09 37.0 0.1 2.2e-08 34.4 0.1 1.8 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM71983.1 - 0.019 14.7 0.2 0.031 14.1 0.2 1.4 1 1 0 1 1 1 0 Reverse transcriptase-like ICAT PF06384.11 KFM71983.1 - 0.084 13.1 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT HTH_48 PF17906.1 KFM71984.1 - 0.0052 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_24 PF13412.6 KFM71984.1 - 0.05 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 KFM71984.1 - 0.075 13.7 0.0 0.2 12.3 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain DUF2043 PF09740.9 KFM71985.1 - 1.2e-34 119.2 2.3 1.5e-34 118.9 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) HTH_Tnp_Tc3_2 PF01498.18 KFM71986.1 - 2.4e-16 59.8 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71986.1 - 1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Hydrolase_6 PF13344.6 KFM71988.1 - 1.9e-33 114.6 0.0 3.3e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM71988.1 - 2.6e-15 56.2 0.0 6e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KFM71988.1 - 4.1e-13 50.1 0.0 1.9e-07 31.6 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFM71988.1 - 8.2e-06 26.0 0.0 0.079 13.0 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KFM71988.1 - 0.038 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.10 KFM71988.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase ABC_membrane_2 PF06472.15 KFM71989.1 - 2.8e-17 63.0 0.2 3.8e-17 62.6 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFM71989.1 - 2.8e-15 57.0 0.0 5.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM71989.1 - 0.0066 16.3 0.3 0.021 14.7 0.1 1.9 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM71989.1 - 0.12 12.2 0.3 0.25 11.1 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane_2 PF06472.15 KFM71990.1 - 0.0084 15.5 0.1 0.01 15.3 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Peptidase_M14 PF00246.24 KFM71991.1 - 2.9e-14 53.6 0.0 4.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KFM71991.1 - 2.1e-10 40.9 0.0 3e-09 37.2 0.0 2.2 1 1 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM71994.1 - 2.2e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM71994.1 - 2.8e-14 53.1 0.0 4.6e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease BTB PF00651.31 KFM71996.1 - 1.2e-34 118.9 1.0 6.1e-26 90.8 1.6 2.5 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFM71996.1 - 9.1e-09 35.4 1.5 1.6e-06 28.1 0.2 2.9 2 0 0 2 2 2 2 BTB And C-terminal Kelch DUF1160 PF06648.11 KFM71996.1 - 0.017 15.1 0.1 0.052 13.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Integrase_H2C2 PF17921.1 KFM71997.1 - 0.0018 18.3 0.1 0.0034 17.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain BTB PF00651.31 KFM71998.1 - 6.9e-35 119.6 3.0 2.2e-26 92.3 0.3 3.1 2 1 1 3 3 3 2 BTB/POZ domain BACK PF07707.15 KFM71998.1 - 0.0001 22.4 4.5 0.00034 20.7 0.5 2.8 3 0 0 3 3 3 1 BTB And C-terminal Kelch DNA_pol3_alpha PF07733.12 KFM71998.1 - 0.038 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain BTB PF00651.31 KFM71999.1 - 1.7e-11 44.3 0.0 3.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 KFM71999.1 - 6.8e-05 23.0 0.1 0.00014 22.0 0.1 1.6 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 KFM72000.1 - 6.6e-28 97.2 0.3 1.1e-27 96.5 0.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM72000.1 - 9.1e-06 25.7 0.1 0.0016 18.5 0.0 2.4 2 0 0 2 2 2 2 BTB And C-terminal Kelch AMP-binding_C_2 PF14535.6 KFM72000.1 - 0.057 13.7 0.0 0.14 12.5 0.0 1.6 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain C2 PF00168.30 KFM72001.1 - 6.4e-22 77.8 0.0 9.8e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 KFM72002.1 - 3e-55 187.4 0.0 4.2e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM72002.1 - 1.9e-32 112.6 0.0 2.4e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFM72002.1 - 2.8e-06 27.9 3.2 7e-06 26.7 3.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFM72002.1 - 0.0069 15.4 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM72002.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KFM72002.1 - 0.016 15.1 0.2 0.029 14.3 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFM72002.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2726 PF10881.8 KFM72004.1 - 0.016 15.1 0.3 52 3.7 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2726) BTB PF00651.31 KFM72007.1 - 5.3e-14 52.4 0.5 9.8e-14 51.5 0.5 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM72007.1 - 0.00017 21.6 1.7 0.0092 16.1 0.3 2.2 2 0 0 2 2 2 2 BTB And C-terminal Kelch YtxC PF08812.11 KFM72007.1 - 0.0013 18.3 0.2 0.0016 18.1 0.2 1.2 1 0 0 1 1 1 1 YtxC-like family BTB PF00651.31 KFM72008.1 - 3.6e-16 59.4 0.0 6.9e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF3707 PF12499.8 KFM72008.1 - 0.11 13.1 0.1 0.21 12.2 0.1 1.4 1 0 0 1 1 1 0 Pherophorin DUF535 PF04393.13 KFM72008.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF535) zf-C2H2_2 PF12756.7 KFM72010.1 - 8.1e-11 42.2 13.8 0.002 18.4 0.3 4.2 3 1 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFM72010.1 - 8.9e-11 41.6 14.6 0.0017 18.7 0.5 4.8 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72010.1 - 5.9e-10 39.1 12.0 0.039 14.8 0.2 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM72010.1 - 1.1e-08 34.8 9.1 0.018 15.0 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HE PF16278.5 KFM72010.1 - 0.015 15.7 6.4 4.8 7.7 0.3 4.0 3 1 1 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF4187 PF13821.6 KFM72010.1 - 0.016 15.0 1.0 6.4 6.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf-FCS PF06467.14 KFM72010.1 - 0.052 13.5 8.0 1.6 8.8 0.3 3.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif BIR PF00653.21 KFM72010.1 - 0.095 13.4 7.5 0.16 12.7 0.2 3.6 4 0 0 4 4 3 0 Inhibitor of Apoptosis domain Sgf11 PF08209.11 KFM72010.1 - 0.1 12.2 0.1 0.1 12.2 0.1 2.8 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) VATC PF18716.1 KFM72010.1 - 0.23 11.4 1.6 21 5.1 0.0 3.0 3 0 0 3 3 3 0 Vms1-associating treble clef domain zf-C2H2_9 PF16293.5 KFM72010.1 - 0.23 11.4 5.4 3.5 7.5 0.1 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-CpG_bind_C PF12269.8 KFM72010.1 - 1.1 9.0 11.4 0.11 12.3 2.7 2.8 2 1 2 4 4 4 0 CpG binding protein zinc finger C terminal domain zf_ZIC PF18366.1 KFM72010.1 - 1.1 9.5 6.4 19 5.4 0.2 3.6 3 1 0 3 3 3 0 Zic proteins zinc finger domain zf_C2HC_14 PF18574.1 KFM72010.1 - 1.6 8.6 4.2 2.3 8.1 0.4 2.6 2 0 0 2 2 2 0 C2HC Zing finger domain Actin_micro PF17003.5 KFM72010.1 - 5 6.2 11.1 0.39 9.9 2.2 3.0 2 1 2 4 4 4 0 Putative actin-like family HypA PF01155.19 KFM72010.1 - 5.2 7.1 9.2 17 5.5 0.2 3.7 3 1 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBR PF01485.21 KFM72010.1 - 6.8 7.0 7.1 8 6.8 0.2 3.2 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DUF4451 PF14616.6 KFM72010.1 - 8.3 6.6 10.5 29 4.9 3.3 4.3 3 2 1 4 4 4 0 Domain of unknown function (DUF4451) PSI_integrin PF17205.3 KFM72010.1 - 9.5 6.1 8.3 3.5 7.4 0.2 3.1 3 0 0 3 3 3 0 Integrin plexin domain zf-C2H2_4 PF13894.6 KFM72011.1 - 0.074 13.9 3.4 0.16 12.9 3.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM72011.1 - 0.18 12.3 3.9 0.39 11.3 3.9 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Actin_micro PF17003.5 KFM72011.1 - 0.25 10.5 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative actin-like family DUF4371 PF14291.6 KFM72012.1 - 2.5e-30 105.9 0.5 5.1e-30 104.8 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM72012.1 - 1.3e-09 37.7 0.2 4.8e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM72012.1 - 0.034 13.1 7.6 0.049 12.6 0.4 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MAT1 PF06391.13 KFM72012.1 - 2.1 8.1 7.7 2.3 8.0 2.0 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4355 PF14265.6 KFM72012.1 - 3 8.1 5.7 3.6 7.8 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Exonuc_VII_L PF02601.15 KFM72012.1 - 5.9 6.4 8.9 6 6.3 1.2 2.9 3 0 0 3 3 3 0 Exonuclease VII, large subunit HTH_Tnp_Tc3_2 PF01498.18 KFM72013.1 - 4.2e-16 58.9 3.5 5.8e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72013.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72013.1 - 2e-07 30.7 1.2 7.2e-07 28.9 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72013.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72013.1 - 2.3 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_5 PF13909.6 KFM72014.1 - 0.0052 16.5 6.9 0.01 15.6 6.9 1.5 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFM72014.1 - 0.1 13.0 5.8 3.8 8.1 1.2 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_7 PF15269.6 KFM72014.1 - 0.16 12.1 5.1 0.22 11.6 5.1 1.2 1 0 0 1 1 1 0 Zinc-finger zf-H2C2_2 PF13465.6 KFM72015.1 - 1.2e-18 66.6 68.3 1.2e-06 28.6 0.8 9.5 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72015.1 - 8.5e-14 51.2 86.2 0.00056 20.2 1.0 9.5 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72015.1 - 3.8e-09 36.6 82.7 0.02 15.7 0.9 9.5 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM72015.1 - 7.1e-07 28.9 59.4 0.00057 19.6 3.1 7.6 7 1 0 7 7 7 4 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM72015.1 - 0.00043 20.5 5.3 0.00043 20.5 5.3 5.6 3 2 3 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFM72015.1 - 0.0012 19.1 4.0 0.0012 19.1 4.0 4.1 2 2 2 4 4 4 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KFM72015.1 - 0.0013 18.4 1.1 0.0013 18.4 1.1 6.0 8 0 0 8 8 7 1 zinc-finger C2H2-type DUF3268 PF11672.8 KFM72015.1 - 0.0052 17.1 0.6 0.0052 17.1 0.6 4.0 3 2 1 4 4 4 1 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 KFM72015.1 - 0.031 14.6 0.1 0.031 14.6 0.1 7.1 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM72015.1 - 0.19 12.1 0.3 0.19 12.1 0.3 6.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Ribosomal_L34e PF01199.18 KFM72015.1 - 9 6.7 9.1 0.26 11.6 0.5 2.9 3 1 1 4 4 4 0 Ribosomal protein L34e ECH_1 PF00378.20 KFM72016.1 - 7.1e-42 143.4 0.0 8.3e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM72016.1 - 3.3e-25 89.3 0.2 1.3e-24 87.3 0.2 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Plectin PF00681.20 KFM72016.1 - 0.051 13.5 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat COBRA PF04833.15 KFM72017.1 - 0.01 15.7 0.2 0.096 12.6 0.0 1.9 1 1 1 2 2 2 0 COBRA-like protein Retinal PF15449.6 KFM72017.1 - 0.12 10.1 0.0 0.13 10.0 0.0 1.0 1 0 0 1 1 1 0 Retinal protein ECH_1 PF00378.20 KFM72019.1 - 2.4e-10 40.2 0.0 2.5e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 KFM72020.1 - 2.1e-30 104.8 0.7 3.6e-30 104.0 0.3 1.5 2 0 0 2 2 2 1 Acyl CoA binding protein ECH_1 PF00378.20 KFM72020.1 - 3.1e-11 43.1 0.1 4.7e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM72020.1 - 1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase COG4 PF08318.12 KFM72021.1 - 2.3e-94 316.2 8.9 5.6e-94 314.9 8.9 1.7 1 0 0 1 1 1 1 COG4 transport protein S-AdoMet_synt_C PF02773.16 KFM72021.1 - 0.033 14.2 0.4 4.8 7.2 0.1 2.6 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, C-terminal domain AAA_assoc PF14363.6 KFM72021.1 - 0.056 13.8 1.8 0.63 10.4 0.1 3.4 2 1 1 3 3 3 0 Domain associated at C-terminal with AAA MotB_plug PF13677.6 KFM72021.1 - 0.085 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB IMS PF00817.20 KFM72021.1 - 0.3 11.1 5.1 0.18 11.8 0.6 3.0 2 2 0 2 2 2 0 impB/mucB/samB family Pullulanase_Ins PF18494.1 KFM72021.1 - 4.5 7.8 6.6 11 6.6 0.2 4.3 4 0 0 4 4 4 0 Pullulanase Ins domain Ada3 PF10198.9 KFM72022.1 - 1.2e-11 44.9 3.7 1.2e-11 44.9 3.7 2.5 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Phostensin PF13914.6 KFM72023.1 - 0.0033 18.1 0.0 0.011 16.3 0.0 1.9 1 0 0 1 1 1 1 Phostensin PP1-binding and SH3-binding region DDE_3 PF13358.6 KFM72024.1 - 4.5e-16 58.9 0.1 4.8e-15 55.6 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72024.1 - 1.5e-10 41.1 1.0 2.7e-10 40.3 1.0 1.4 1 0 0 1 1 1 1 Transposase Hormone_recep PF00104.30 KFM72025.1 - 4e-42 144.2 0.0 5.6e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TMEM214 PF10151.9 KFM72027.1 - 3.8e-144 481.7 10.1 4.7e-144 481.4 10.1 1.0 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator TFIIA PF03153.13 KFM72028.1 - 1.1e-19 71.7 0.4 1.3e-19 71.6 0.4 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Kinesin_assoc PF16183.5 KFM72028.1 - 0.0096 16.1 0.1 0.0096 16.1 0.1 1.1 1 0 0 1 1 1 1 Kinesin-associated TFIIA PF03153.13 KFM72029.1 - 6.6e-57 194.4 2.7 8.8e-57 194.0 2.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 KFM72029.1 - 0.04 12.0 12.6 0.043 11.9 12.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KFM72029.1 - 0.26 9.5 11.0 0.31 9.2 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KFM72029.1 - 0.59 9.4 13.1 0.79 9.0 13.1 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KFM72029.1 - 1.2 8.6 9.9 1.3 8.3 9.9 1.1 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 KFM72029.1 - 1.2 8.9 8.1 1.6 8.5 8.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.10 KFM72029.1 - 2.1 7.6 8.7 2.4 7.4 8.7 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KFM72029.1 - 3.8 5.7 8.5 4.4 5.5 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 KFM72029.1 - 6.8 6.5 11.8 10 6.0 11.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CREPT PF16566.5 KFM72030.1 - 0.14 12.4 0.2 0.14 12.4 0.2 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour NTPase_I-T PF01931.18 KFM72032.1 - 4.3e-11 42.9 0.0 6.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF84 SapB_1 PF05184.15 KFM72033.1 - 0.17 11.9 0.0 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 Saposin-like type B, region 1 Mad3_BUB1_I PF08311.12 KFM72034.1 - 2.5e-39 134.1 0.6 5.6e-39 133.0 0.6 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KFM72034.1 - 7.8e-19 68.1 2.0 1.7e-18 66.9 2.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM72034.1 - 2.5e-11 43.3 0.2 4.7e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S7 PF00177.21 KFM72035.1 - 1.2e-39 135.3 0.1 1.6e-39 135.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e PKD_2 PF16407.5 KFM72035.1 - 0.015 15.5 0.0 0.024 14.8 0.0 1.5 1 1 0 1 1 1 0 PKD-like family DSBA PF01323.20 KFM72035.1 - 0.03 14.1 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain PAS_11 PF14598.6 KFM72036.1 - 5.6e-29 100.5 0.5 1.2e-23 83.4 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KFM72036.1 - 3.2e-08 33.6 0.0 7.4e-06 25.9 0.0 3.3 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KFM72036.1 - 6.6e-08 32.7 0.0 0.0029 17.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFM72036.1 - 1.9e-05 24.5 0.7 4.9e-05 23.2 0.7 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFM72036.1 - 0.00056 20.1 0.1 0.033 14.4 0.0 2.8 2 0 0 2 2 2 1 PAS domain Gtr1_RagA PF04670.12 KFM72037.1 - 2.9e-49 167.5 0.1 3.2e-49 167.4 0.1 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KFM72037.1 - 4.5e-08 33.3 0.0 6.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM72037.1 - 1e-07 31.7 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFM72037.1 - 5.3e-07 29.7 0.0 5.8e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFM72037.1 - 1.5e-06 27.8 0.0 1.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 KFM72037.1 - 0.0092 15.7 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KFM72037.1 - 0.0096 16.4 0.0 0.0096 16.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter G-alpha PF00503.20 KFM72037.1 - 0.011 15.0 2.5 1.2 8.3 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 KFM72037.1 - 0.019 14.7 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFM72037.1 - 0.024 13.8 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KFM72037.1 - 0.079 12.5 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KFM72037.1 - 0.086 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 KFM72037.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 KFM72037.1 - 0.11 12.3 0.5 0.17 11.7 0.5 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPR PF01535.20 KFM72039.1 - 0.0032 17.6 0.0 0.048 13.9 0.1 2.9 3 0 0 3 3 3 1 PPR repeat Syntaxin-6_N PF09177.11 KFM72039.1 - 0.011 16.3 0.8 0.14 12.7 0.1 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PPR_2 PF13041.6 KFM72039.1 - 0.034 14.3 0.1 0.17 12.1 0.2 2.1 2 0 0 2 2 2 0 PPR repeat family DUF3319 PF11782.8 KFM72039.1 - 0.18 11.8 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) Ras PF00071.22 KFM72041.1 - 4.1e-51 172.8 0.0 4.9e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM72041.1 - 3.4e-33 114.4 0.0 5.4e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM72041.1 - 2.3e-15 56.5 0.0 2.9e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM72041.1 - 2e-08 33.9 0.0 5e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM72041.1 - 5.6e-08 32.9 0.0 8.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFM72041.1 - 7.7e-06 25.6 0.1 0.00082 19.0 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFM72041.1 - 2.1e-05 24.0 0.0 3.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFM72041.1 - 0.00012 21.4 0.3 0.0033 16.6 0.2 2.3 1 1 1 2 2 2 1 G-protein alpha subunit TniB PF05621.11 KFM72041.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.7 1 1 0 1 1 1 1 Bacterial TniB protein Sof1 PF04158.14 KFM72042.1 - 7.4e-34 115.9 13.1 1.3e-33 115.1 13.1 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KFM72042.1 - 1.4e-22 79.5 10.0 4.7e-05 24.1 1.3 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM72042.1 - 1.5e-08 34.8 0.1 0.028 14.7 0.0 4.4 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM72042.1 - 0.00011 22.2 0.0 0.2 11.5 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 KFM72042.1 - 0.0015 18.5 0.1 9.1 6.4 0.0 4.2 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Coatomer_WDAD PF04053.14 KFM72042.1 - 0.02 13.9 0.0 0.29 10.1 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region Nup160 PF11715.8 KFM72042.1 - 0.035 12.8 0.1 0.13 10.9 0.0 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 NARP1 PF12569.8 KFM72043.1 - 4.9e-218 725.2 20.8 4.9e-218 725.2 20.8 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KFM72043.1 - 7.2e-16 57.0 25.4 0.0055 16.7 0.0 9.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFM72043.1 - 2.9e-15 55.1 13.7 0.0029 17.7 0.0 7.3 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFM72043.1 - 1.1e-11 45.1 14.1 0.0039 17.7 0.2 6.7 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM72043.1 - 1.9e-11 43.3 27.9 0.0083 15.9 0.1 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFM72043.1 - 2e-09 37.5 6.2 2.1 9.4 0.2 8.7 6 2 3 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM72043.1 - 3.7e-08 33.5 21.3 0.012 15.8 1.7 7.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM72043.1 - 3.9e-08 32.9 2.7 0.00018 21.1 0.0 5.0 5 0 0 5 5 5 1 TPR repeat TPR_9 PF13371.6 KFM72043.1 - 1.5e-07 31.4 7.4 0.063 13.4 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM72043.1 - 1.2e-06 28.6 23.0 0.0049 17.1 0.6 5.7 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFM72043.1 - 0.00011 22.3 3.4 0.4 11.2 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM72043.1 - 0.00014 21.2 6.6 0.0025 17.1 0.3 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM72043.1 - 0.00014 21.6 12.6 0.13 12.4 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM72043.1 - 0.00034 20.1 1.5 0.099 12.0 0.1 3.0 2 1 0 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 KFM72043.1 - 0.00066 20.3 6.4 25 5.6 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 KFM72043.1 - 0.005 16.9 4.3 4.5 7.4 0.0 5.1 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KFM72043.1 - 0.038 13.9 6.7 29 4.7 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM72043.1 - 0.043 14.5 14.1 9.9 7.0 0.1 7.4 8 1 0 8 8 7 0 Tetratricopeptide repeat MAS20 PF02064.15 KFM72043.1 - 0.091 12.9 3.5 1.1 9.4 4.1 2.5 2 0 0 2 2 2 0 MAS20 protein import receptor Pox_H7 PF04787.12 KFM72043.1 - 0.92 10.0 4.5 1.2 9.6 1.7 2.6 2 0 0 2 2 2 0 Late protein H7 Fis1_TPR_C PF14853.6 KFM72043.1 - 1.5 8.9 8.0 1.2e+02 2.9 0.1 5.2 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat Zona_pellucida PF00100.23 KFM72044.1 - 2.4e-19 70.1 0.4 3.5e-19 69.6 0.4 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain BPL_LplA_LipB PF03099.19 KFM72045.1 - 8.7e-09 35.4 0.1 1.4e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Scramblase PF03803.15 KFM72046.1 - 9.3e-83 276.9 0.0 1.1e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 Scramblase DUF4186 PF13811.6 KFM72046.1 - 0.45 10.6 0.1 0.45 10.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4186) Ig_3 PF13927.6 KFM72047.1 - 3.4e-07 30.8 1.1 7.2e-07 29.7 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM72047.1 - 0.00023 21.4 0.6 0.00063 20.0 0.6 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM72047.1 - 0.0013 18.9 1.0 0.0033 17.6 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 KFM72047.1 - 0.0018 17.8 0.5 0.0047 16.5 0.5 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM72047.1 - 0.013 15.7 0.2 0.045 13.9 0.2 2.0 1 1 0 1 1 1 0 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM72047.1 - 0.061 13.7 0.4 0.16 12.4 0.4 1.6 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pam16 PF03656.13 KFM72048.1 - 3.2e-44 150.0 2.6 3.5e-44 149.9 2.6 1.0 1 0 0 1 1 1 1 Pam16 Integrase_Zn PF02022.19 KFM72048.1 - 0.032 14.2 1.0 4.2 7.4 1.4 2.4 2 0 0 2 2 2 0 Integrase Zinc binding domain LEA_3 PF03242.13 KFM72048.1 - 0.3 11.8 2.6 0.34 11.7 2.1 1.4 1 1 0 1 1 1 0 Late embryogenesis abundant protein Fzo_mitofusin PF04799.13 KFM72049.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region ABA_GPCR PF12430.8 KFM72050.1 - 1e-40 139.4 10.1 1e-40 139.4 10.1 1.8 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KFM72050.1 - 4.5e-25 87.5 0.6 1.7e-24 85.7 0.1 2.2 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Herpes_UL95 PF03038.14 KFM72051.1 - 0.0061 15.7 0.0 0.0065 15.7 0.0 1.0 1 0 0 1 1 1 1 UL95 family Sec2p PF06428.11 KFM72053.1 - 0.031 14.2 0.5 0.057 13.4 0.5 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Peptidase_C14 PF00656.22 KFM72054.1 - 6.6e-16 59.0 0.2 3e-15 56.8 0.1 1.8 1 1 0 2 2 2 1 Caspase domain CARD PF00619.21 KFM72054.1 - 0.088 12.8 0.0 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 Caspase recruitment domain RNase_H PF00075.24 KFM72055.1 - 2.9e-05 24.3 0.0 2.9e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 RNase H SelP_N PF04592.14 KFM72056.1 - 1.5e-24 86.7 0.5 1.5e-24 86.7 0.5 2.5 2 0 0 2 2 2 2 Selenoprotein P, N terminal region HTH_Tnp_Tc3_2 PF01498.18 KFM72057.1 - 2.4e-16 59.7 2.2 4.2e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72057.1 - 1.7e-12 47.3 0.0 3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease I-set PF07679.16 KFM72059.1 - 3.5e-14 52.6 0.0 1.4e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM72059.1 - 6.2e-14 52.4 0.0 1.6e-11 44.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM72059.1 - 1.1e-09 38.3 0.0 4.8e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM72059.1 - 2.3e-09 37.5 0.0 3.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM72059.1 - 9.6e-07 28.8 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFM72059.1 - 8.7e-06 25.7 0.0 2.3e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 C17orf99 Ig domain Ig_6 PF18452.1 KFM72059.1 - 0.043 13.4 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFM72060.1 - 3.3e-11 43.1 0.0 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM72060.1 - 7e-10 39.4 0.1 0.00029 21.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM72060.1 - 5.7e-09 36.2 0.0 0.0022 18.3 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM72060.1 - 1.5e-07 31.6 0.0 0.00036 20.7 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 KFM72060.1 - 4.2e-07 30.0 0.0 0.0029 17.8 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFM72060.1 - 0.1 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Ig_5 PF16681.5 KFM72060.1 - 0.12 12.8 0.0 5 7.6 0.0 2.1 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain HTH_Tnp_Tc3_2 PF01498.18 KFM72061.1 - 3.6e-16 59.2 7.1 7.7e-16 58.1 5.0 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72061.1 - 1.4e-09 37.8 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 KFM72061.1 - 1.3e-06 28.4 1.5 1.3e-05 25.3 0.0 3.1 2 1 2 4 4 4 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM72061.1 - 7.2e-06 26.5 3.9 7.2e-06 26.5 3.9 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KFM72061.1 - 1.3e-05 25.1 0.3 0.0017 18.4 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM72061.1 - 7.9e-05 22.3 0.0 7.9e-05 22.3 0.0 4.1 5 0 0 5 5 4 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM72061.1 - 0.0017 18.0 0.5 0.0067 16.0 0.0 2.3 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 KFM72061.1 - 0.0033 17.2 0.0 0.012 15.4 0.0 2.0 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_38 PF13936.6 KFM72061.1 - 0.011 15.5 0.1 0.043 13.6 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 KFM72061.1 - 0.011 15.6 0.8 0.035 14.0 0.0 2.2 3 0 0 3 3 3 0 MarR family HTH_Tnp_Tc3_1 PF11427.8 KFM72061.1 - 0.068 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Tc3 transposase Sigma70_r4 PF04545.16 KFM72061.1 - 0.1 12.2 1.3 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 Tox-REase-7 PF15649.6 KFM72061.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 SOAR PF16533.5 KFM72062.1 - 3.5e-42 142.5 0.2 3.5e-42 142.5 0.2 3.3 4 1 0 4 4 4 1 STIM1 Orai1-activating region DUF3290 PF11694.8 KFM72062.1 - 0.011 15.7 0.9 0.15 12.1 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) DUF4446 PF14584.6 KFM72062.1 - 0.019 14.9 1.4 0.019 14.9 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Ribosomal_S17 PF00366.20 KFM72062.1 - 0.068 13.3 0.2 0.55 10.4 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S17 DUF1616 PF07760.11 KFM72062.1 - 0.11 11.8 0.2 0.18 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) GntR PF00392.21 KFM72062.1 - 0.19 11.4 0.6 0.45 10.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF4407 PF14362.6 KFM72062.1 - 0.57 9.5 9.4 0.88 8.9 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KFM72062.1 - 1 9.7 17.0 6.1 7.2 9.5 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3829 PF12889.7 KFM72062.1 - 2 7.8 16.5 0.18 11.3 10.9 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3829) DHR10 PF18595.1 KFM72062.1 - 8.1 6.5 27.3 1.6 8.8 0.8 3.4 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain DUF4845 PF16137.5 KFM72062.1 - 8.4 7.3 8.1 3.4 8.6 2.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4845) JUPITER PF17054.5 KFM72063.1 - 1e-11 44.9 8.8 5.5e-10 39.3 0.0 3.3 2 1 1 3 3 3 2 Microtubule-Associated protein Jupiter CN_hydrolase PF00795.22 KFM72064.1 - 2.4e-10 40.2 0.0 3.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Proteasome PF00227.26 KFM72065.1 - 1.1e-41 142.4 0.0 1.3e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MHC_II_alpha PF00993.20 KFM72066.1 - 0.045 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain Retrotran_gag_2 PF14223.6 KFM72067.1 - 1.7e-13 50.4 2.1 3.6e-13 49.4 2.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KFM72067.1 - 4.9e-06 26.3 0.8 1.6e-05 24.7 0.8 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain Urocanase PF01175.18 KFM72069.1 - 1.1e-81 273.5 0.0 2.2e-81 272.5 0.0 1.5 2 0 0 2 2 2 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 KFM72069.1 - 6.5e-77 257.4 0.2 9.5e-77 256.9 0.2 1.2 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase_N PF17391.2 KFM72069.1 - 1.9e-55 186.0 0.2 4e-55 184.9 0.2 1.6 1 0 0 1 1 1 1 Urocanase N-terminal domain DUF3668 PF12416.8 KFM72072.1 - 0.0045 16.8 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Cep120 protein DUF3668 PF12416.8 KFM72073.1 - 5.4e-22 78.7 0.0 2.2e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 Cep120 protein C2 PF00168.30 KFM72073.1 - 0.15 12.3 0.1 0.34 11.2 0.0 1.6 2 0 0 2 2 2 0 C2 domain LRR_8 PF13855.6 KFM72075.1 - 6.2e-27 93.1 2.4 3.9e-13 48.9 0.2 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM72075.1 - 4.7e-14 52.3 4.9 2.3e-05 24.7 0.0 4.9 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM72075.1 - 1.7e-10 41.0 0.0 8.5e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM72075.1 - 2.8e-07 30.2 0.3 0.00056 19.4 0.0 2.6 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 KFM72075.1 - 4.3e-07 29.6 3.5 28 5.8 0.0 7.7 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.6 KFM72075.1 - 0.058 13.5 5.1 15 5.9 0.0 5.0 5 1 0 5 5 5 0 Leucine Rich repeat DUF2269 PF10027.9 KFM72076.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) LRR_8 PF13855.6 KFM72077.1 - 2.7e-21 75.1 2.7 2.2e-08 33.7 0.0 4.8 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 KFM72077.1 - 7.1e-09 35.4 0.3 0.00031 20.3 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFM72077.1 - 2.8e-08 33.9 4.8 0.021 15.2 0.0 4.7 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM72077.1 - 1.1e-06 28.6 0.0 4.5e-05 23.4 0.0 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM72077.1 - 0.00023 21.3 1.2 28 5.8 0.0 6.2 5 1 0 5 5 5 1 Leucine Rich Repeat PIG-H PF10181.9 KFM72078.1 - 1.1e-16 60.4 0.6 1.8e-16 59.8 0.1 1.7 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component Lantibiotic_a PF14867.6 KFM72078.1 - 0.00032 20.4 0.8 0.00063 19.4 0.8 1.5 1 0 0 1 1 1 1 Lantibiotic alpha N-glycanase_C PF09113.10 KFM72078.1 - 0.1 12.3 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal DUF2768 PF10966.8 KFM72078.1 - 0.13 12.7 0.2 0.13 12.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) ARL2_Bind_BART PF11527.8 KFM72079.1 - 2.6e-12 46.9 0.7 2.6e-12 46.9 0.7 2.0 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Asp-B-Hydro_N PF05279.11 KFM72079.1 - 0.51 10.4 24.0 0.92 9.5 24.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Macoilin PF09726.9 KFM72079.1 - 0.68 8.4 14.0 0.81 8.2 14.0 1.1 1 0 0 1 1 1 0 Macoilin family PP2C_C PF07830.13 KFM72079.1 - 2.5 8.6 18.0 1.3 9.5 1.5 3.3 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain CUB PF00431.20 KFM72081.1 - 2e-24 86.0 0.2 1.8e-17 63.6 0.1 2.1 2 0 0 2 2 2 2 CUB domain DDE_3 PF13358.6 KFM72082.1 - 3.7e-16 59.2 0.2 5.7e-15 55.3 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72082.1 - 6.7e-16 58.3 6.5 1.5e-15 57.2 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72082.1 - 0.00095 19.7 1.5 0.00095 19.7 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain Ras PF00071.22 KFM72083.1 - 1.5e-55 187.2 0.1 2e-55 186.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM72083.1 - 3.4e-34 117.6 0.1 5e-34 117.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM72083.1 - 8.4e-17 61.2 0.1 1e-16 60.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM72083.1 - 1.9e-05 24.3 0.1 0.00011 21.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM72083.1 - 0.00016 21.8 0.1 0.00038 20.5 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFM72083.1 - 0.0003 20.7 0.9 0.0059 16.4 0.1 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 KFM72083.1 - 0.0012 18.2 0.0 0.0014 18.0 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFM72083.1 - 0.0021 18.0 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFM72083.1 - 0.0037 16.7 0.0 0.0065 15.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KFM72083.1 - 0.014 14.9 0.2 0.13 11.8 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SOGA PF11365.8 KFM72084.1 - 0.11 13.6 1.2 0.86 10.8 0.7 2.1 2 0 0 2 2 2 0 Protein SOGA ATP-synt_C PF00137.21 KFM72085.1 - 1.8e-24 85.9 40.6 4.6e-13 49.3 14.7 2.7 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 KFM72085.1 - 0.16 11.3 1.9 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 zf-H2C2_2 PF13465.6 KFM72086.1 - 6.7e-59 193.8 65.8 1.8e-08 34.4 0.5 10.1 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72086.1 - 1.4e-45 151.3 81.8 8.3e-06 26.0 1.6 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72086.1 - 6.7e-32 107.4 77.4 0.00087 19.9 1.4 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM72086.1 - 1.4e-20 73.0 62.4 0.00081 19.7 0.3 9.9 8 1 1 9 9 9 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM72086.1 - 3.3e-16 59.1 52.3 0.032 14.5 0.2 9.8 9 1 1 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM72086.1 - 7.2e-15 54.6 66.6 0.013 15.5 2.1 9.4 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM72086.1 - 1.6e-06 27.8 35.6 0.18 11.6 0.1 8.7 3 1 6 9 9 9 3 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFM72086.1 - 1.8e-06 28.2 61.7 0.36 11.2 1.2 8.9 1 1 8 9 9 9 5 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFM72086.1 - 5.6e-06 26.1 18.4 0.48 10.3 0.0 7.4 2 1 7 9 9 9 1 GAGA factor zf-CHCC PF10276.9 KFM72086.1 - 7.4e-05 22.7 8.5 11 6.2 0.0 7.3 8 0 0 8 8 8 0 Zinc-finger domain BolA PF01722.18 KFM72086.1 - 0.00041 20.6 10.3 0.95 9.8 0.2 5.1 1 1 2 4 4 4 2 BolA-like protein zf-RRPl_C4 PF17026.5 KFM72086.1 - 0.00093 19.3 31.3 0.59 10.3 4.8 4.0 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type FYVE PF01363.21 KFM72086.1 - 0.0013 18.9 42.9 0.15 12.2 6.8 4.6 3 1 1 4 4 4 3 FYVE zinc finger Tox-HNH-HHH PF15637.6 KFM72086.1 - 0.0092 16.1 0.4 5.6 7.2 0.0 3.2 1 1 2 3 3 3 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-MYST PF17772.1 KFM72086.1 - 0.012 15.2 43.6 0.045 13.4 0.6 8.8 6 3 3 9 9 9 0 MYST family zinc finger domain HNH_5 PF14279.6 KFM72086.1 - 0.02 14.8 38.1 0.29 11.0 0.3 8.4 7 2 1 8 8 8 0 HNH endonuclease ADK_lid PF05191.14 KFM72086.1 - 0.5 10.4 33.7 4.7 7.3 0.1 6.3 3 2 1 4 4 3 0 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM72086.1 - 0.61 10.2 34.6 9.7 6.4 0.1 8.5 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM72086.1 - 1.5 9.0 36.6 14 5.9 0.1 8.5 9 0 0 9 9 9 0 DBF zinc finger XPA_N PF01286.18 KFM72086.1 - 1.5 8.9 33.5 3.9 7.6 0.1 8.3 9 0 0 9 9 9 0 XPA protein N-terminal zf-HIT PF04438.16 KFM72086.1 - 2.2 8.2 48.0 7.2 6.6 0.4 8.9 9 0 0 9 9 9 0 HIT zinc finger TRAF6_Z2 PF18048.1 KFM72086.1 - 2.7 8.2 34.8 4.2 7.5 1.5 8.4 9 0 0 9 9 9 0 TNF receptor-associated factor 6 zinc finger 2 zf-Sec23_Sec24 PF04810.15 KFM72086.1 - 3.1 7.9 29.9 2.5 8.2 0.1 8.1 9 0 0 9 9 9 0 Sec23/Sec24 zinc finger Flag1_repress PF03614.13 KFM72086.1 - 3.8 7.3 8.8 21 4.9 0.1 3.9 1 1 0 3 3 3 0 Repressor of phase-1 flagellin DUF3337 PF11816.8 KFM72087.1 - 8.1e-22 77.9 0.0 9e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) Ribosomal_60s PF00428.19 KFM72087.1 - 0.017 15.7 0.7 0.023 15.3 0.7 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein RAWUL PF16207.5 KFM72087.1 - 0.18 12.5 0.0 0.25 12.1 0.0 1.2 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF3337 PF11816.8 KFM72088.1 - 0.25 11.2 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) WD40 PF00400.32 KFM72089.1 - 2.7e-05 24.8 0.0 0.0035 18.1 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat DNase_NucA_NucB PF14040.6 KFM72092.1 - 0.032 14.6 0.1 0.044 14.2 0.1 1.1 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB DUF1216 PF06746.11 KFM72092.1 - 0.048 13.7 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) Skp1_POZ PF03931.15 KFM72092.1 - 0.28 11.4 2.4 0.24 11.6 1.1 1.5 1 1 0 1 1 1 0 Skp1 family, tetramerisation domain adh_short_C2 PF13561.6 KFM72093.1 - 6.1e-67 225.6 0.2 7.4e-67 225.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM72093.1 - 1.4e-54 184.5 0.9 1.9e-54 184.1 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM72093.1 - 4e-20 72.5 0.2 6e-20 71.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFM72093.1 - 0.0029 16.8 0.1 0.0047 16.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFM72093.1 - 0.0046 16.1 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFM72093.1 - 0.0072 15.8 0.0 0.0098 15.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KFM72093.1 - 0.035 14.0 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPF0146 PF03686.13 KFM72093.1 - 0.081 12.8 0.0 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) GDP_Man_Dehyd PF16363.5 KFM72093.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase UQ_con PF00179.26 KFM72095.1 - 1e-20 73.8 0.0 2.1e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM72095.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B MBT PF02820.18 KFM72096.1 - 1.4e-84 278.4 0.4 5.9e-21 74.6 0.2 4.2 4 0 0 4 4 4 4 mbt repeat STIMATE PF12400.8 KFM72097.1 - 5.8e-08 33.3 0.1 1.2e-07 32.4 0.1 1.5 1 0 0 1 1 1 1 STIMATE family STIMATE PF12400.8 KFM72098.1 - 0.0011 19.5 0.2 0.0011 19.5 0.2 1.0 1 0 0 1 1 1 1 STIMATE family HTH_Tnp_Tc3_2 PF01498.18 KFM72099.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72099.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PSS PF03034.15 KFM72100.1 - 2.5e-45 155.4 6.6 2.7e-45 155.3 6.6 1.0 1 0 0 1 1 1 1 Phosphatidyl serine synthase Runt PF00853.19 KFM72104.1 - 6.6e-35 119.5 0.0 7.8e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 Runt domain PapA_C PF16911.5 KFM72105.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus FH2 PF02181.23 KFM72106.1 - 8.7e-100 334.4 11.9 8.7e-100 334.4 11.9 2.9 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KFM72106.1 - 4.1e-41 140.7 15.1 1.3e-40 139.2 15.1 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFM72106.1 - 9.3e-24 84.0 9.2 9.3e-24 84.0 9.2 4.8 4 2 0 4 4 4 1 Diaphanous GTPase-binding Domain zf-C4H2 PF10146.9 KFM72106.1 - 0.0016 18.8 2.7 0.0016 18.8 2.7 3.3 3 1 0 3 3 3 1 Zinc finger-containing protein MafB19-deam PF14437.6 KFM72106.1 - 0.02 14.6 0.3 0.07 12.9 0.3 1.9 1 0 0 1 1 1 0 MafB19-like deaminase DDHD PF02862.17 KFM72106.1 - 0.48 10.6 5.7 19 5.3 0.0 2.3 2 0 0 2 2 2 0 DDHD domain PMEI PF04043.15 KFM72106.1 - 1.9 8.8 6.2 0.58 10.5 1.5 2.6 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Crust_neurohorm PF01147.17 KFM72107.1 - 4.7e-28 96.8 7.1 7.3e-28 96.2 7.1 1.3 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family Topoisom_I_N PF02919.15 KFM72107.1 - 0.1 12.1 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Crust_neurohorm PF01147.17 KFM72108.1 - 4.6e-28 96.8 6.8 6.3e-28 96.4 6.8 1.2 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family Topoisom_I_N PF02919.15 KFM72108.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Crust_neurohorm PF01147.17 KFM72109.1 - 2.4e-14 52.9 1.0 3.6e-14 52.3 1.0 1.3 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family PH_16 PF17838.1 KFM72110.1 - 0.098 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 PH domain HNOB PF07700.15 KFM72111.1 - 4.9e-11 42.8 0.0 5.2e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Haem-NO-binding DUF5315 PF17242.2 KFM72111.1 - 0.098 12.5 0.0 0.098 12.5 0.0 1.1 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) HTH_Tnp_Tc3_2 PF01498.18 KFM72112.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72112.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72112.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72112.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72112.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM72113.1 - 5.8e-16 58.5 2.2 5.8e-16 58.5 2.2 2.3 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM72113.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72113.1 - 3.3e-08 33.2 1.4 9.7e-08 31.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72113.1 - 0.00078 19.2 0.8 0.0022 17.7 0.8 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72113.1 - 0.51 11.0 16.4 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain tRNA_int_endo PF01974.17 KFM72114.1 - 3e-19 68.9 0.1 8.2e-19 67.5 0.1 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KFM72114.1 - 5e-10 38.9 0.3 6.3e-05 22.6 0.1 2.6 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Strabismus PF06638.11 KFM72114.1 - 0.99 8.0 3.8 1.4 7.5 3.8 1.1 1 0 0 1 1 1 0 Strabismus protein FYDLN_acid PF09538.10 KFM72114.1 - 3.7 8.3 11.7 15 6.3 10.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) HTH_Tnp_Tc3_2 PF01498.18 KFM72116.1 - 7.3e-16 58.2 6.5 1.3e-15 57.4 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72116.1 - 2.1e-15 56.7 0.0 5.2e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM72116.1 - 0.00066 20.2 1.5 0.00066 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72116.1 - 0.0036 17.1 0.3 0.11 12.3 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72116.1 - 0.017 15.2 0.1 0.06 13.5 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM72116.1 - 0.031 14.3 2.6 0.032 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix CRAL_TRIO_N PF03765.15 KFM72117.1 - 0.00011 22.3 0.2 0.00014 22.0 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM72118.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72118.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CRAL_TRIO PF00650.20 KFM72119.1 - 1.4e-33 115.9 0.0 1.9e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM72119.1 - 6.5e-07 29.4 0.4 1.5e-06 28.3 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM72119.1 - 0.00017 21.8 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain GOLD_2 PF13897.6 KFM72119.1 - 0.041 14.4 0.0 0.071 13.6 0.0 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking HTH_Tnp_Tc3_2 PF01498.18 KFM72120.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72120.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Cation_efflux PF01545.21 KFM72121.1 - 2e-49 168.0 17.0 2.5e-49 167.7 17.0 1.1 1 0 0 1 1 1 1 Cation efflux family I-set PF07679.16 KFM72123.1 - 2.3e-19 69.2 0.2 1.5e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM72123.1 - 5.1e-19 68.6 2.3 1.8e-11 44.5 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM72123.1 - 1.6e-14 53.8 1.3 3.8e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM72123.1 - 1.6e-13 50.8 2.4 2.2e-06 27.8 0.5 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM72123.1 - 3.9e-11 43.1 1.5 2.6e-07 30.9 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFM72123.1 - 2.1e-06 28.0 1.6 0.00036 20.8 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFM72123.1 - 1.9e-05 25.0 0.0 0.058 13.8 0.0 2.8 2 2 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM72123.1 - 0.0011 19.1 0.2 1.4 9.2 0.0 3.0 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFM72123.1 - 0.0027 17.3 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Receptor_2B4 PF11465.8 KFM72123.1 - 0.027 14.7 0.1 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 HTH_Tnp_Tc3_2 PF01498.18 KFM72124.1 - 5.9e-18 64.9 3.5 1.1e-17 64.0 3.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72124.1 - 1.8e-12 47.3 0.0 3.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM72124.1 - 0.00038 21.0 1.1 0.00038 21.0 1.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM72124.1 - 0.00065 19.7 0.8 0.034 14.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_33 PF13592.6 KFM72124.1 - 0.0071 16.0 0.3 0.021 14.5 0.3 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KFM72124.1 - 0.0073 16.4 1.0 1.7 8.8 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 KFM72124.1 - 0.034 14.0 1.8 2 8.3 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_26 PF13443.6 KFM72124.1 - 0.17 12.4 0.4 16 6.0 0.2 2.5 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 KFM72124.1 - 0.31 10.6 1.7 7 6.3 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 KFM72125.1 - 4.5e-16 58.9 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72125.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72125.1 - 1.9e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72125.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72125.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM72126.1 - 6.9e-16 58.3 0.1 7.4e-15 55.0 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72126.1 - 1.3e-10 41.4 1.0 2.7e-10 40.4 1.0 1.6 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM72128.1 - 5.2e-16 58.6 2.2 5.2e-16 58.6 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM72128.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72128.1 - 1.9e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72128.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72128.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Filament PF00038.21 KFM72129.1 - 0.0031 17.1 76.5 0.02 14.5 20.0 4.2 1 1 3 4 4 4 2 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 KFM72129.1 - 0.0058 16.9 19.4 0.0058 16.9 19.4 4.6 1 1 3 4 4 4 1 JNK_SAPK-associated protein-1 DUF3642 PF12182.8 KFM72129.1 - 2.4 8.5 11.0 0.3 11.4 2.3 3.0 3 0 0 3 3 3 0 Bacterial lipoprotein DUF4320 PF14208.6 KFM72129.1 - 8.2 6.5 8.3 2.2 8.4 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) Pkinase PF00069.25 KFM72131.1 - 6.1e-59 199.5 0.0 7.2e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM72131.1 - 1.2e-30 106.7 0.0 1.5e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM72131.1 - 7.4e-10 38.6 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM72131.1 - 1.9e-05 23.8 0.0 2.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM72131.1 - 0.00077 19.5 0.7 0.0054 16.7 0.6 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFM72131.1 - 0.014 14.5 0.2 0.026 13.6 0.2 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KFM72131.1 - 0.021 14.2 0.5 0.045 13.1 0.1 1.7 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFM72131.1 - 0.059 12.1 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Mucin-like PF16058.5 KFM72133.1 - 2e-08 34.2 15.9 2.8e-08 33.7 15.9 1.3 1 0 0 1 1 1 1 Mucin-like PHD PF00628.29 KFM72134.1 - 3.8e-07 29.9 15.4 4.6e-07 29.6 13.4 1.9 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 KFM72134.1 - 0.00012 21.5 12.4 0.0017 17.9 6.3 2.1 2 0 0 2 2 2 2 PHD-finger C1_2 PF03107.16 KFM72134.1 - 0.0014 18.9 3.7 0.0014 18.9 3.7 1.8 2 0 0 2 2 2 1 C1 domain C1_1 PF00130.22 KFM72134.1 - 0.0033 17.3 6.7 0.0033 17.3 6.7 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) bZIP_Maf PF03131.17 KFM72135.1 - 8.3e-17 61.5 5.5 1.7e-16 60.5 5.5 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFM72135.1 - 6.3e-07 29.4 3.8 6.3e-07 29.4 3.8 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFM72135.1 - 0.0029 17.7 5.8 0.0029 17.7 5.8 2.0 2 0 0 2 2 2 1 Basic region leucine zipper DDE_3 PF13358.6 KFM72136.1 - 9.7e-08 31.9 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Phosphorylase PF00343.20 KFM72138.1 - 0 1166.4 0.0 0 1166.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DDE_3 PF13358.6 KFM72139.1 - 1.2e-13 51.1 0.0 1.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72139.1 - 9.8e-08 32.1 1.6 3.9e-06 27.0 2.1 2.4 2 0 0 2 2 2 1 Transposase MFS_1 PF07690.16 KFM72140.1 - 9.9e-21 74.0 33.9 9.9e-21 74.0 33.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily HTH_Tnp_Tc3_2 PF01498.18 KFM72141.1 - 6.9e-17 61.5 2.7 1.4e-16 60.5 2.7 1.5 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM72141.1 - 0.00084 19.4 3.6 0.0011 19.1 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_3 PF13358.6 KFM72141.1 - 0.0034 17.2 0.1 1 9.1 0.0 3.3 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM72141.1 - 0.032 14.0 0.9 0.54 10.1 0.1 2.7 2 0 0 2 2 2 0 Homeodomain-like domain CENP-B_N PF04218.13 KFM72141.1 - 0.036 13.7 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_ISL3 PF13542.6 KFM72141.1 - 0.4 10.1 0.1 0.4 10.1 0.1 3.1 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 FOXP-CC PF16159.5 KFM72142.1 - 0.011 16.4 0.5 0.013 16.1 0.5 1.1 1 0 0 1 1 1 0 FOXP coiled-coil domain Bacteroid_pep PF14406.6 KFM72142.1 - 0.21 12.0 0.9 0.21 12.0 0.9 2.3 2 1 0 3 3 3 0 Ribosomally synthesized peptide in Bacteroidetes HTH_Tnp_Tc3_2 PF01498.18 KFM72146.1 - 5.5e-16 58.6 2.2 1.4e-15 57.3 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72146.1 - 4.1e-13 49.3 0.0 7.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease FYVE PF01363.21 KFM72146.1 - 2.2e-09 37.3 8.7 2.2e-09 37.3 8.7 1.8 2 0 0 2 2 2 1 FYVE zinc finger HTH_38 PF13936.6 KFM72146.1 - 1.5e-06 27.9 0.2 1.5e-06 27.9 0.2 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain zinc_ribbon_9 PF14369.6 KFM72146.1 - 0.0021 18.3 2.0 0.0054 17.0 2.0 1.7 1 0 0 1 1 1 1 zinc-ribbon HTH_23 PF13384.6 KFM72146.1 - 0.0065 16.2 0.5 0.016 15.0 0.5 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72146.1 - 0.074 13.2 0.5 0.21 11.8 0.5 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain zf-RING_2 PF13639.6 KFM72146.1 - 0.33 11.3 7.7 1.2 9.5 7.7 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 KFM72146.1 - 2.1 8.6 5.7 3.2 8.0 3.9 2.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Acyl-CoA_dh_1 PF00441.24 KFM72147.1 - 1.4e-29 103.2 0.1 3.2e-29 102.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 KFM72147.1 - 2.6e-17 63.2 0.0 4.4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM72147.1 - 4.9e-14 52.3 0.0 9.8e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM72147.1 - 3.2e-08 33.9 0.0 5.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HTH_3 PF01381.22 KFM72147.1 - 0.13 12.4 0.1 0.57 10.3 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix Ras PF00071.22 KFM72148.1 - 1.7e-47 161.0 0.0 1.9e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM72148.1 - 4.1e-23 81.9 0.0 5.1e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM72148.1 - 1.3e-09 37.8 0.0 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM72148.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM72148.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ldh_1_N PF00056.23 KFM72148.1 - 0.06 13.4 0.0 12 6.0 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain GTP_EFTU PF00009.27 KFM72148.1 - 0.091 12.3 0.1 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Lipoxygenase PF00305.19 KFM72149.1 - 5.2e-61 206.9 0.0 8.8e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.23 KFM72149.1 - 1.9e-16 60.6 0.2 4e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain GpcrRhopsn4 PF10192.9 KFM72150.1 - 4.5e-05 23.0 6.6 8.1e-05 22.1 6.6 1.5 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain COX15-CtaA PF02628.15 KFM72150.1 - 0.0024 17.0 0.0 0.0035 16.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF2207 PF09972.9 KFM72150.1 - 0.004 16.0 6.1 0.32 9.7 0.1 2.1 1 1 1 2 2 2 2 Predicted membrane protein (DUF2207) ALS2CR11 PF15729.5 KFM72150.1 - 1.7 7.7 6.7 2.3 7.3 6.7 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 SSTK-IP PF15836.5 KFM72151.1 - 0.15 12.2 0.2 0.15 12.2 0.2 1.0 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Ricin_B_lectin PF00652.22 KFM72152.1 - 5.4e-06 26.7 0.1 6.4e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain zf-H2C2_2 PF13465.6 KFM72153.1 - 3.8e-78 254.7 96.6 2e-08 34.3 0.7 13.1 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72153.1 - 5e-56 184.2 115.7 2.6e-06 27.6 2.0 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72153.1 - 2e-40 133.9 107.7 0.00035 21.2 1.1 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM72153.1 - 3.2e-23 81.3 105.3 0.0013 19.1 2.4 12.2 12 0 0 12 12 12 11 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM72153.1 - 4.6e-20 71.0 66.1 0.028 14.1 0.2 12.9 12 1 0 12 12 12 9 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM72153.1 - 1.7e-15 56.8 75.8 0.042 14.1 0.2 12.2 12 1 0 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM72153.1 - 1.8e-10 40.6 93.4 0.00011 22.0 0.3 12.6 12 1 0 12 12 12 7 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM72153.1 - 1.1e-09 38.0 58.9 0.79 9.6 1.1 11.5 3 2 9 12 12 12 8 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM72153.1 - 2.9e-08 33.9 21.9 0.5 10.7 0.1 7.6 1 1 6 7 7 7 4 BolA-like protein zf-RRPl_C4 PF17026.5 KFM72153.1 - 4.9e-07 29.8 50.4 0.023 14.8 3.7 5.2 1 1 5 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type GAGA PF09237.11 KFM72153.1 - 0.0002 21.1 23.1 1.3 8.9 0.1 9.0 1 1 9 11 11 11 1 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM72153.1 - 0.00026 21.0 41.4 9.5 6.4 0.1 10.9 8 2 4 12 12 12 0 Sec23/Sec24 zinc finger Tox-HNH-HHH PF15637.6 KFM72153.1 - 0.0023 18.0 6.5 12 6.1 0.0 4.9 1 1 5 6 6 6 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_11 PF16622.5 KFM72153.1 - 0.0055 16.4 79.2 0.016 15.0 0.1 11.9 12 0 0 12 12 12 5 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM72153.1 - 0.026 14.4 49.5 1.1 9.2 0.2 10.3 11 1 0 11 11 10 0 zinc-finger of a C2HC-type Complex1_49kDa PF00346.19 KFM72153.1 - 0.028 13.5 4.5 2.7 7.0 0.1 3.3 1 1 2 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zinc_ribbon_15 PF17032.5 KFM72153.1 - 0.091 13.5 52.4 10 7.0 1.9 6.6 1 1 6 7 7 7 0 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM72153.1 - 0.18 12.1 96.5 1.6 9.1 1.1 11.8 1 1 11 12 12 12 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KFM72153.1 - 2 8.6 65.5 0.68 10.1 8.9 6.1 1 1 5 7 7 7 0 FYVE zinc finger DUF2256 PF10013.9 KFM72153.1 - 2.7 8.2 48.8 18 5.5 0.7 10.9 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) TRAF6_Z2 PF18048.1 KFM72153.1 - 3 8.0 64.2 0.062 13.4 3.1 11.5 12 0 0 12 12 12 0 TNF receptor-associated factor 6 zinc finger 2 C1_1 PF00130.22 KFM72153.1 - 4.9 7.1 78.0 7.1 6.6 0.4 10.6 2 2 8 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HLH PF00010.26 KFM72154.1 - 6e-17 61.3 4.3 7.5e-17 61.0 4.3 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DDE_3 PF13358.6 KFM72156.1 - 1.4e-15 57.3 0.1 3.2e-15 56.1 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72156.1 - 1.5e-10 41.2 1.0 2.8e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM72157.1 - 5.1e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72157.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72157.1 - 2.2e-07 30.5 1.2 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72157.1 - 0.0029 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72157.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain PBD PF00786.28 KFM72158.1 - 2.1e-17 63.2 0.0 4.3e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Ets PF00178.22 KFM72159.1 - 8e-37 125.6 0.6 2.4e-36 124.0 0.6 1.9 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFM72159.1 - 2.7e-27 94.6 0.2 7.4e-27 93.2 0.1 1.8 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain PEN-2 PF10251.9 KFM72160.1 - 4.5e-32 110.3 4.6 5e-32 110.2 4.6 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase RVT_1 PF00078.27 KFM72161.1 - 2.2e-09 37.2 0.0 2.2e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FERM_C PF09380.10 KFM72162.1 - 3.1e-25 88.4 0.0 6.4e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain 4_1_CTD PF05902.13 KFM72162.1 - 1.6e-23 82.8 7.4 1.6e-23 82.8 7.4 2.8 2 1 0 2 2 2 1 4.1 protein C-terminal domain (CTD) FERM_M PF00373.18 KFM72162.1 - 3.5e-21 75.8 0.8 1.4e-20 73.8 0.2 2.2 2 0 0 2 2 2 1 FERM central domain FA PF08736.11 KFM72162.1 - 1.4e-17 63.5 2.1 4.1e-17 62.0 2.1 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 KFM72162.1 - 5.4e-15 55.1 0.2 2.6e-14 52.9 0.1 2.3 2 0 0 2 2 2 1 FERM N-terminal domain EF-hand_1 PF00036.32 KFM72164.1 - 1.2e-12 46.3 3.8 1.4e-05 24.3 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFM72164.1 - 2.8e-12 46.9 5.0 1.2e-11 44.9 1.6 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFM72164.1 - 4e-12 45.0 2.7 6.1e-05 22.6 0.2 3.4 3 1 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFM72164.1 - 3.4e-10 38.9 0.4 0.00082 18.8 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFM72164.1 - 2.9e-05 23.8 3.6 0.019 14.8 1.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM72164.1 - 0.00012 22.3 0.2 0.0004 20.7 0.1 1.8 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFM72164.1 - 0.019 15.2 0.0 0.096 12.9 0.0 1.6 1 1 1 2 2 2 0 Dockerin type I domain Salt_tol_Pase PF09506.10 KFM72164.1 - 0.027 13.3 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) EF-hand_4 PF12763.7 KFM72164.1 - 0.085 12.8 1.9 1.7 8.6 0.0 2.6 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand PHD PF00628.29 KFM72165.1 - 1e-09 38.1 6.0 3.2e-09 36.5 6.0 2.0 1 0 0 1 1 1 1 PHD-finger DDE_3 PF13358.6 KFM72166.1 - 7.1e-16 58.3 0.1 8.9e-15 54.7 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72166.1 - 9.8e-16 57.8 6.5 2e-15 56.8 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72166.1 - 0.00096 19.7 1.5 0.00096 19.7 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72166.1 - 0.0044 16.8 0.1 0.15 11.9 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72166.1 - 0.018 15.2 0.1 0.083 13.0 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM72166.1 - 0.045 13.8 0.4 0.045 13.8 0.4 2.4 3 0 0 3 3 3 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM72167.1 - 3.3e-15 56.1 1.7 5.8e-15 55.3 1.7 1.4 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM72167.1 - 7e-05 22.9 2.5 0.00022 21.3 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72167.1 - 0.0016 18.2 0.4 0.078 12.8 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KFM72167.1 - 0.022 14.1 0.7 0.097 12.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 KFM72167.1 - 0.038 13.6 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain PAX PF00292.18 KFM72167.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain Aldo_ket_red PF00248.21 KFM72168.1 - 2.2e-59 201.1 0.1 3.4e-59 200.4 0.1 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family DDE_3 PF13358.6 KFM72169.1 - 6.4e-16 58.4 0.1 6.1e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72169.1 - 7.4e-16 58.2 6.5 1.5e-15 57.2 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72169.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72169.1 - 0.0028 17.4 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72169.1 - 0.016 15.3 0.1 0.067 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM72169.1 - 0.037 14.1 0.4 0.037 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM72170.1 - 6.4e-16 58.4 6.5 1e-15 57.7 6.5 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72170.1 - 0.0005 20.6 1.5 0.0005 20.6 1.5 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72170.1 - 0.01 15.6 2.1 0.086 12.7 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.6 KFM72170.1 - 0.014 15.5 0.1 0.047 13.8 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM72170.1 - 0.019 15.0 2.4 0.025 14.6 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM72170.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DDE_3 PF13358.6 KFM72171.1 - 1.9e-11 43.9 0.0 3.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease TACC_C PF05010.14 KFM72172.1 - 3e-29 102.3 38.8 5.4e-29 101.4 38.8 1.4 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Aconitase_C PF00694.19 KFM72172.1 - 0.035 14.4 6.8 0.34 11.2 2.6 2.9 1 1 1 2 2 2 0 Aconitase C-terminal domain ASL_C PF08328.11 KFM72172.1 - 0.042 13.9 2.9 0.12 12.5 2.9 1.8 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal ADIP PF11559.8 KFM72172.1 - 0.19 11.8 33.9 0.07 13.2 16.3 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HTH_6 PF01418.17 KFM72172.1 - 0.22 11.5 7.4 1 9.4 2.7 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Spc7 PF08317.11 KFM72172.1 - 0.28 10.0 35.8 0.16 10.9 19.3 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein BRX_N PF13713.6 KFM72172.1 - 0.33 10.7 6.3 0.085 12.6 0.9 2.7 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain GAS PF13851.6 KFM72172.1 - 0.72 9.2 41.1 0.031 13.6 30.5 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ArAE_2_N PF10337.9 KFM72172.1 - 1.2 8.1 9.2 1.9 7.5 9.2 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Lebercilin PF15619.6 KFM72172.1 - 2 8.1 42.6 0.4 10.3 29.9 2.9 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 KFM72172.1 - 2.1 8.1 37.2 2.2 8.0 10.9 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Las1 PF04031.13 KFM72173.1 - 2.6e-41 141.3 1.3 3.6e-41 140.8 1.3 1.2 1 0 0 1 1 1 1 Las1-like RNase_Zc3h12a PF11977.8 KFM72175.1 - 2.2e-65 219.2 0.0 4e-65 218.4 0.0 1.5 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFM72175.1 - 1e-16 60.6 0.8 2.6e-16 59.3 0.2 2.0 2 0 0 2 2 2 1 UBA-like domain Regnase_1_C PF18561.1 KFM72175.1 - 1.5e-07 31.0 0.0 4.4e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain zf-CCCH_4 PF18044.1 KFM72175.1 - 0.00036 20.2 7.1 0.00068 19.4 7.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KFM72175.1 - 0.031 14.2 6.0 0.11 12.5 6.0 1.9 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PRORP PF16953.5 KFM72175.1 - 0.039 13.5 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-only RNase P DUF5615 PF18480.1 KFM72175.1 - 0.14 11.9 0.0 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5615) Omega-toxin PF06357.11 KFM72175.1 - 0.92 9.4 5.6 2 8.3 5.6 1.5 1 0 0 1 1 1 0 Omega-atracotoxin Ldt_C PF17969.1 KFM72175.1 - 1.9 9.3 4.6 13 6.6 0.0 2.9 3 0 0 3 3 3 0 L,D-transpeptidase C-terminal domain zf_CCCH_4 PF18345.1 KFM72175.1 - 2.2 8.4 7.1 6.8 6.9 7.1 1.9 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 KFM72175.1 - 3.4 8.3 9.9 7 7.3 9.9 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RVT_1 PF00078.27 KFM72176.1 - 5.3e-05 22.8 0.0 0.00011 21.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Homeodomain PF00046.29 KFM72177.1 - 3.2e-21 74.9 5.7 5e-21 74.3 5.7 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFM72177.1 - 0.057 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Myc_target_1 PF15179.6 KFM72178.1 - 0.025 14.5 0.3 0.026 14.4 0.3 1.1 1 0 0 1 1 1 0 Myc target protein 1 DDE_3 PF13358.6 KFM72179.1 - 5.7e-16 58.6 0.1 6.3e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72179.1 - 8.3e-16 58.0 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72179.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72179.1 - 0.0015 18.3 0.0 0.062 13.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72179.1 - 0.013 15.6 0.1 0.049 13.8 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM72179.1 - 0.024 14.6 2.1 0.033 14.2 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM72179.1 - 0.029 14.2 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase HTH_Tnp_Tc3_2 PF01498.18 KFM72180.1 - 4.2e-16 58.9 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72180.1 - 2.5e-11 43.5 0.0 4.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72180.1 - 2.7e-07 30.2 1.8 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72180.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72180.1 - 2.1 9.1 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Spond_N PF06468.13 KFM72181.1 - 1.2e-66 224.6 0.1 2e-66 223.8 0.1 1.4 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 KFM72181.1 - 2.4e-06 27.7 2.0 5.6e-06 26.5 2.0 1.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain DDE_3 PF13358.6 KFM72182.1 - 1.8e-12 47.2 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TACC_C PF05010.14 KFM72183.1 - 5.2e-41 140.7 26.4 5.2e-41 140.7 26.4 1.8 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Lzipper-MIP1 PF14389.6 KFM72183.1 - 0.0055 17.0 8.0 0.0055 17.0 8.0 2.9 2 1 1 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 Prefoldin_2 PF01920.20 KFM72183.1 - 0.3 11.0 20.4 0.34 10.9 5.4 3.8 3 1 0 3 3 3 0 Prefoldin subunit DUF745 PF05335.13 KFM72183.1 - 0.71 9.6 15.4 0.39 10.4 11.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 KFM72183.1 - 0.86 9.6 9.2 0.61 10.1 4.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KFM72183.1 - 3.1 7.0 17.0 1.3e+02 1.7 16.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) cwf21 PF08312.12 KFM72183.1 - 6.5 7.0 9.3 8.8 6.6 1.9 3.3 2 0 0 2 2 2 0 cwf21 domain SH3BP5 PF05276.14 KFM72184.1 - 2.3e-89 299.2 24.5 3.9e-89 298.4 24.5 1.4 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF948 PF06103.11 KFM72184.1 - 0.17 12.2 3.1 0.36 11.1 0.2 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) AvrPphF-ORF-2 PF09143.10 KFM72184.1 - 0.2 11.6 2.1 1.1 9.2 0.2 2.4 1 1 1 2 2 2 0 AvrPphF-ORF-2 UCR_hinge PF02320.16 KFM72184.1 - 2.7 8.2 5.8 2.1 8.6 0.3 3.1 4 0 0 4 4 4 0 Ubiquinol-cytochrome C reductase hinge protein CP2 PF04516.15 KFM72185.1 - 3.3e-44 150.9 0.8 5.1e-44 150.3 0.8 1.3 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFM72185.1 - 5.6e-18 64.5 0.0 3.5e-17 62.0 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Prokineticin PF06607.11 KFM72188.1 - 5.7e-05 23.4 5.8 7e-05 23.1 5.8 1.1 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM72188.1 - 0.0082 16.7 6.4 0.013 16.1 6.4 1.3 1 0 0 1 1 1 1 MIT-like atracotoxin family Colipase_C PF02740.14 KFM72188.1 - 0.024 14.8 0.2 0.024 14.8 0.2 2.4 3 0 0 3 3 3 0 Colipase, C-terminal domain zf-TFIIIC PF12660.7 KFM72189.1 - 0.078 12.9 0.2 0.088 12.8 0.2 1.2 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Importin_rep PF18773.1 KFM72189.1 - 0.079 12.7 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Importin 13 repeat Syntaxin_2 PF14523.6 KFM72190.1 - 0.0015 18.9 1.1 0.0061 16.9 0.0 2.5 3 0 0 3 3 3 1 Syntaxin-like protein Mod_r PF07200.13 KFM72190.1 - 0.04 14.0 4.1 0.081 13.0 0.1 2.4 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF2161 PF09929.9 KFM72190.1 - 0.22 11.6 1.2 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) FAM184 PF15665.5 KFM72190.1 - 0.25 11.1 3.6 1.7 8.4 0.1 2.3 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 KFM72190.1 - 0.76 9.0 4.0 8 5.6 0.1 2.2 2 0 0 2 2 2 0 TMPIT-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM72191.1 - 2.3e-16 59.8 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72191.1 - 9.5e-14 51.4 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72192.1 - 5.1e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72192.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72192.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72192.1 - 0.0027 17.4 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72192.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 KFM72193.1 - 9.4e-38 127.0 54.6 3.1e-08 33.7 1.0 7.8 8 1 0 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72193.1 - 2.3e-25 87.6 73.3 1.3e-05 25.4 2.1 7.2 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72193.1 - 2e-20 71.7 63.1 0.00076 20.1 2.1 7.2 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 KFM72193.1 - 2.7e-17 62.5 59.3 0.0026 18.1 0.9 7.7 8 0 0 8 8 7 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM72193.1 - 1.9e-14 53.2 45.5 0.059 13.4 0.3 7.4 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM72193.1 - 1.2e-09 38.2 47.9 0.0036 17.6 0.3 7.3 7 1 0 7 7 6 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM72193.1 - 7.7e-08 32.0 38.0 0.0021 17.7 0.5 7.7 7 0 0 7 7 7 4 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM72193.1 - 1.4e-05 24.9 28.5 0.032 14.2 2.5 5.9 3 3 2 5 5 5 2 Adenylate kinase, active site lid GAGA PF09237.11 KFM72193.1 - 0.00012 21.8 25.1 0.043 13.6 0.1 6.3 1 1 6 7 7 7 3 GAGA factor Mga PF05043.13 KFM72193.1 - 0.00015 22.3 0.2 7.1 7.3 0.0 4.0 3 1 1 4 4 4 1 Mga helix-turn-helix domain BolA PF01722.18 KFM72193.1 - 0.00088 19.5 5.3 2.7 8.3 0.6 4.5 1 1 4 5 5 5 1 BolA-like protein Tox-HNH-HHH PF15637.6 KFM72193.1 - 0.0071 16.5 0.6 5.4 7.2 0.0 3.4 1 1 3 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif PqqA PF08042.11 KFM72193.1 - 0.017 15.2 0.6 49 4.2 0.1 4.1 5 0 0 5 5 5 0 PqqA family A_deaminase PF00962.22 KFM72193.1 - 0.052 12.9 6.5 6 6.1 0.5 3.3 1 1 1 3 3 3 0 Adenosine/AMP deaminase Ndufs5 PF10200.9 KFM72193.1 - 0.41 10.9 8.6 3.5 7.9 1.0 3.6 1 1 3 4 4 4 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa C1_1 PF00130.22 KFM72193.1 - 2.8 7.9 47.2 11 6.0 7.6 7.0 3 3 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFM72193.1 - 4.2 7.1 36.2 0.4 10.3 0.6 7.0 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger Ta0938 PF11494.8 KFM72193.1 - 6.2 7.2 26.9 7.6 6.9 0.4 6.3 1 1 4 5 5 5 0 Ta0938 zf_ZIC PF18366.1 KFM72193.1 - 8.8 6.5 31.6 0.53 10.4 0.3 6.2 1 1 6 7 7 7 0 Zic proteins zinc finger domain RhoGEF PF00621.20 KFM72194.1 - 3.3e-36 125.2 2.0 3.3e-36 125.2 2.0 3.0 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 KFM72194.1 - 7.7e-19 67.6 7.4 1.9e-18 66.3 7.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFM72194.1 - 3.3e-12 46.9 19.7 2.1e-10 41.1 0.0 5.6 5 0 0 5 5 5 2 PH domain IQ_SEC7_PH PF16453.5 KFM72194.1 - 1.4e-05 25.1 0.7 7.5e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFM72194.1 - 0.0014 19.1 4.4 0.52 10.8 1.4 4.4 3 0 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 KFM72194.1 - 0.0066 16.7 0.0 0.042 14.1 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain FYVE_2 PF02318.16 KFM72194.1 - 1.4 9.2 10.6 2.5 8.3 8.6 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger DZR PF12773.7 KFM72194.1 - 5.6 7.1 7.1 16 5.6 7.1 1.8 1 1 0 1 1 1 0 Double zinc ribbon HTH_Tnp_Tc3_2 PF01498.18 KFM72195.1 - 6.8e-22 77.5 7.1 6.1e-16 58.4 2.2 2.4 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM72195.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PH PF00169.29 KFM72196.1 - 0.0023 18.4 0.0 0.0024 18.3 0.0 1.0 1 0 0 1 1 1 1 PH domain SPRY PF00622.28 KFM72197.1 - 3.2e-24 85.3 0.3 5.4e-24 84.6 0.3 1.4 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 KFM72197.1 - 4.7e-06 26.4 12.4 4.7e-06 26.4 12.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM72197.1 - 0.0071 16.2 12.9 0.0071 16.2 12.9 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM72197.1 - 0.23 11.8 19.5 0.017 15.5 13.1 2.6 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 KFM72197.1 - 0.56 10.1 17.5 0.72 9.8 14.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFM72197.1 - 5.3 7.0 22.9 0.066 13.1 14.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hist_deacetyl PF00850.19 KFM72198.1 - 1.8e-83 280.6 0.1 2.7e-83 280.0 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RNA_polI_A34 PF08208.11 KFM72198.1 - 0.3 11.2 9.7 0.46 10.6 9.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.9 KFM72198.1 - 5.8 6.8 12.2 13 5.7 10.6 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 HTH_Tnp_Tc3_2 PF01498.18 KFM72199.1 - 4.5e-16 58.9 2.2 4.5e-16 58.9 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72199.1 - 1.6e-12 47.4 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM72200.1 - 3.8e-10 39.7 0.0 6.9e-10 38.9 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Snf7 PF03357.21 KFM72201.1 - 2.8e-12 46.6 11.6 3.2e-12 46.4 11.6 1.1 1 0 0 1 1 1 1 Snf7 FbpA PF05833.11 KFM72201.1 - 0.007 15.2 5.7 0.007 15.2 5.7 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) GNVR PF13807.6 KFM72201.1 - 0.019 14.9 1.5 0.023 14.6 1.5 1.2 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase PTPlike_phytase PF14566.6 KFM72201.1 - 0.023 14.8 1.5 0.025 14.7 1.5 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF5352 PF17303.2 KFM72201.1 - 0.07 13.0 0.8 0.081 12.8 0.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5352) MCU PF04678.13 KFM72201.1 - 0.1 12.7 2.3 0.12 12.5 2.3 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1090 PF06476.12 KFM72201.1 - 0.19 11.9 10.5 0.11 12.6 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) Exonuc_VII_L PF02601.15 KFM72201.1 - 0.43 10.1 5.8 0.48 9.9 5.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0767 PF15990.5 KFM72201.1 - 0.83 9.8 3.5 1.4 9.1 3.5 1.6 1 1 0 1 1 1 0 UPF0767 family DDE_3 PF13358.6 KFM72202.1 - 2e-08 34.1 0.3 2.8e-08 33.6 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Helicase_RecD PF05127.14 KFM72202.1 - 0.099 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Helicase NEMO PF11577.8 KFM72202.1 - 0.11 12.5 0.8 0.19 11.8 0.8 1.3 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO zf-H2C2_2 PF13465.6 KFM72203.1 - 4e-48 159.8 47.2 7.8e-08 32.4 2.0 7.2 6 1 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72203.1 - 6.4e-29 98.8 58.3 4.7e-05 23.6 1.9 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72203.1 - 7.2e-19 66.9 56.2 0.001 19.7 1.6 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM72203.1 - 4.8e-15 55.4 49.5 0.0057 17.0 1.4 7.2 7 0 0 7 7 7 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM72203.1 - 7.2e-11 42.1 37.5 0.019 15.2 0.5 7.3 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-RRPl_C4 PF17026.5 KFM72203.1 - 9.9e-06 25.6 22.7 0.033 14.3 6.3 3.4 1 1 1 2 2 2 2 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_6 PF13912.6 KFM72203.1 - 1.3e-05 25.0 45.2 0.015 15.2 0.7 7.6 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM72203.1 - 0.0029 17.4 22.2 0.56 10.1 0.2 5.8 1 1 5 6 6 6 2 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM72203.1 - 0.0039 17.2 17.7 13 5.9 0.5 6.2 4 3 3 7 7 7 0 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM72203.1 - 0.016 15.0 13.8 2.9 7.7 0.1 5.8 1 1 6 7 7 7 0 GAGA factor DUF2256 PF10013.9 KFM72203.1 - 0.027 14.6 25.6 12 6.2 0.3 6.8 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CHCC PF10276.9 KFM72203.1 - 0.049 13.7 11.8 47 4.1 0.0 6.2 7 0 0 7 7 7 0 Zinc-finger domain PqqA PF08042.11 KFM72203.1 - 0.095 12.8 0.9 33 4.7 0.0 3.9 4 0 0 4 4 4 0 PqqA family zf-C2H2_2 PF12756.7 KFM72203.1 - 0.13 12.6 42.9 0.92 9.9 1.2 6.2 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-FPG_IleRS PF06827.14 KFM72203.1 - 0.23 11.3 15.2 13 5.8 0.1 6.3 7 0 0 7 7 7 0 Zinc finger found in FPG and IleRS zinc_ribbon_15 PF17032.5 KFM72203.1 - 0.28 12.0 22.5 2.9 8.7 1.8 3.8 1 1 4 5 5 5 0 zinc-ribbon family DZR PF12773.7 KFM72203.1 - 0.37 10.9 21.3 1.8e+04 -9.3 21.3 4.2 1 1 0 1 1 0 0 Double zinc ribbon zf-HIT PF04438.16 KFM72203.1 - 0.42 10.5 35.5 12 5.9 0.6 7.0 7 0 0 7 7 7 0 HIT zinc finger zf-DBF PF07535.12 KFM72203.1 - 0.48 10.6 31.1 11 6.2 0.2 6.9 7 0 0 7 7 7 0 DBF zinc finger FYVE PF01363.21 KFM72203.1 - 1.6 8.9 32.5 4.1e+02 1.2 10.5 4.0 1 1 1 2 2 1 0 FYVE zinc finger Zf_RING PF16744.5 KFM72203.1 - 2.6 8.2 30.0 15 5.8 0.3 6.6 1 1 5 6 6 6 0 KIAA1045 RING finger ADK_lid PF05191.14 KFM72203.1 - 5.9 7.0 25.2 3.9 7.5 1.9 5.1 4 2 1 5 5 5 0 Adenylate kinase, active site lid C5HCH PF17982.1 KFM72203.1 - 7.1 6.9 30.1 4.7 7.4 1.4 6.5 4 2 2 7 7 7 0 NSD Cys-His rich domain zf-C2HC_2 PF13913.6 KFM72203.1 - 7.6 6.6 25.3 1.3 9.0 0.7 6.6 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFM72204.1 - 1e-37 126.9 30.5 8.1e-09 35.5 1.0 5.1 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72204.1 - 3.3e-25 87.1 40.2 2.1e-07 31.0 1.4 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72204.1 - 9e-17 60.3 38.5 4.9e-05 23.8 1.3 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM72204.1 - 1.1e-10 41.1 27.2 0.0017 18.0 0.2 5.7 5 1 0 5 5 5 4 C2H2-type zinc-finger domain zf-met PF12874.7 KFM72204.1 - 4e-08 33.4 28.6 0.0054 17.1 1.8 4.6 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM72204.1 - 7.6e-07 29.3 26.2 0.1 12.9 0.4 4.4 2 1 2 4 4 4 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM72204.1 - 1.4e-05 24.8 9.0 0.12 12.2 0.1 4.4 1 1 4 5 5 5 2 GAGA factor zf-C2H2_6 PF13912.6 KFM72204.1 - 8e-05 22.5 30.8 0.024 14.6 2.0 5.2 4 1 0 4 4 4 2 C2H2-type zinc finger Zf_RING PF16744.5 KFM72204.1 - 0.00045 20.3 16.5 0.15 12.1 0.1 4.0 1 1 3 4 4 4 2 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KFM72204.1 - 0.00059 20.1 26.7 0.18 12.2 1.6 3.8 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KFM72204.1 - 0.0019 18.3 11.1 0.0019 18.3 11.1 2.3 1 1 1 2 2 2 1 FYVE zinc finger zf-C2HC_2 PF13913.6 KFM72204.1 - 0.0024 17.7 5.9 0.22 11.5 0.1 3.9 4 0 0 4 4 3 1 zinc-finger of a C2HC-type BolA PF01722.18 KFM72204.1 - 0.003 17.8 4.4 0.52 10.6 0.5 3.3 1 1 1 2 2 2 1 BolA-like protein DUF2256 PF10013.9 KFM72204.1 - 0.0097 16.0 13.8 2.5 8.3 0.2 4.2 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2256) TRAF6_Z2 PF18048.1 KFM72204.1 - 0.014 15.4 2.7 0.014 15.4 2.7 4.9 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 zf-RRPl_C4 PF17026.5 KFM72204.1 - 0.023 14.8 12.9 1.2 9.3 12.9 2.1 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-Paramyx-P PF13008.7 KFM72204.1 - 0.026 14.0 6.2 22 4.6 0.1 4.1 4 0 0 4 4 4 0 Zinc-binding domain of Paramyxoviridae V protein C1_1 PF00130.22 KFM72204.1 - 0.034 14.0 21.5 2.3 8.2 1.2 3.7 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 KFM72204.1 - 0.038 13.7 0.6 0.038 13.7 0.6 4.9 5 0 0 5 5 5 0 zinc-finger C2H2-type Baculo_IE-1 PF05290.11 KFM72204.1 - 0.048 13.6 11.4 0.18 11.7 9.9 2.6 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_9 PF16293.5 KFM72204.1 - 0.058 13.2 13.3 1.3 8.9 0.2 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (1 copy) Complex1_49kDa PF00346.19 KFM72204.1 - 0.098 11.7 0.1 1.8 7.6 0.0 1.9 1 1 1 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Zn-ribbon_8 PF09723.10 KFM72204.1 - 0.31 11.2 10.3 0.5 10.5 2.0 3.2 2 1 1 3 3 3 0 Zinc ribbon domain C1_4 PF07975.12 KFM72204.1 - 0.42 10.9 16.0 0.42 10.9 1.5 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain ADK_lid PF05191.14 KFM72204.1 - 0.45 10.5 11.5 15 5.6 0.3 3.3 2 1 0 2 2 2 0 Adenylate kinase, active site lid FYDLN_acid PF09538.10 KFM72204.1 - 0.53 11.0 7.5 41 4.9 1.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-Dof PF02701.15 KFM72204.1 - 0.61 10.3 0.1 0.61 10.3 0.1 3.5 2 1 1 3 3 3 0 Dof domain, zinc finger Zn_ribbon_SprT PF17283.2 KFM72204.1 - 0.87 9.5 10.2 10 6.1 0.2 3.6 2 2 1 3 3 3 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 KFM72204.1 - 0.9 9.6 12.8 95 3.1 13.0 2.8 1 1 1 2 2 2 0 zinc-ribbons HNH_5 PF14279.6 KFM72204.1 - 0.91 9.4 12.0 27 4.7 2.2 3.9 3 1 0 3 3 3 0 HNH endonuclease zf-HIT PF04438.16 KFM72204.1 - 1.3 9.0 19.7 6.5 6.7 0.4 4.2 4 0 0 4 4 4 0 HIT zinc finger XPA_N PF01286.18 KFM72204.1 - 1.6 8.8 12.7 5.1 7.2 0.2 4.4 5 0 0 5 5 5 0 XPA protein N-terminal DUF5330 PF17264.2 KFM72204.1 - 1.7 8.7 8.6 16 5.6 0.2 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5330) zinc_ribbon_15 PF17032.5 KFM72204.1 - 1.9 9.3 13.0 3.7 8.4 1.5 2.3 1 1 1 2 2 2 0 zinc-ribbon family zf-DBF PF07535.12 KFM72204.1 - 1.9 8.7 11.6 2.7 8.2 0.1 3.6 4 0 0 4 4 3 0 DBF zinc finger C5HCH PF17982.1 KFM72204.1 - 2.2 8.5 14.2 11 6.2 0.7 4.1 3 1 0 4 4 4 0 NSD Cys-His rich domain zf_UBZ PF18439.1 KFM72204.1 - 3.2 7.4 14.9 0.8 9.4 0.2 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger NADH-G_4Fe-4S_3 PF10588.9 KFM72204.1 - 7.2 6.2 11.9 10 5.7 0.5 4.0 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-BED PF02892.15 KFM72204.1 - 7.6 6.7 30.0 1.6 8.9 2.9 4.6 1 1 3 4 4 4 0 BED zinc finger RRM_1 PF00076.22 KFM72205.1 - 0.061 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) rve PF00665.26 KFM72206.1 - 1.2e-14 54.5 0.0 1.5e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain CIDE-N PF02017.15 KFM72206.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 CIDE-N domain GATA PF00320.27 KFM72207.1 - 6e-27 93.0 25.5 7.1e-15 54.3 6.5 2.9 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFM72207.1 - 0.0011 18.4 11.4 0.036 13.6 1.1 2.9 3 0 0 3 3 3 2 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 KFM72207.1 - 0.011 15.6 6.3 0.92 9.5 0.3 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 KFM72207.1 - 0.13 12.4 4.0 3.5 7.8 0.1 3.2 3 0 0 3 3 3 0 Zinc ribbon domain Vps36-NZF-N PF16988.5 KFM72207.1 - 0.58 9.6 4.1 0.52 9.7 0.3 2.9 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Auto_anti-p27 PF06677.12 KFM72207.1 - 1 9.6 10.4 2.2 8.5 0.2 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KFM72207.1 - 2.1 8.3 9.0 1.1 9.1 0.8 2.8 3 0 0 3 3 3 0 Domain found in IF2B/IF5 DZR PF12773.7 KFM72207.1 - 3 7.9 9.4 17 5.5 0.2 3.2 2 1 2 4 4 4 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.12 KFM72207.1 - 3.1 8.2 8.5 1.2 9.5 1.1 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase RVT_1 PF00078.27 KFM72209.1 - 0.022 14.2 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FA_hydroxylase PF04116.13 KFM72211.1 - 2e-22 80.0 17.1 2e-22 80.0 17.1 2.0 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily HTH_Tnp_Tc3_2 PF01498.18 KFM72212.1 - 1e-13 51.3 1.9 2.2e-13 50.2 1.9 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72212.1 - 1.7e-11 44.0 0.0 2.8e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM72212.1 - 0.0037 17.8 2.3 0.0037 17.8 2.3 2.8 3 0 0 3 3 3 1 Homeodomain-like domain PAX PF00292.18 KFM72212.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain HTH_3 PF01381.22 KFM72212.1 - 0.019 15.0 0.7 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix HTH_28 PF13518.6 KFM72212.1 - 0.25 11.5 2.4 3.3 7.9 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2428 PF10350.9 KFM72214.1 - 3.4e-61 206.9 0.0 4.2e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KFM72215.1 - 0.018 15.2 0.2 0.12 12.6 0.1 2.2 2 0 0 2 2 2 0 HEAT repeat DUF4885 PF16226.5 KFM72216.1 - 0.012 14.7 0.2 0.016 14.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) Globin PF00042.22 KFM72217.1 - 3.4e-18 66.2 0.3 4.6e-18 65.8 0.3 1.2 1 0 0 1 1 1 1 Globin DUF4375 PF14300.6 KFM72217.1 - 0.0027 18.0 2.4 0.028 14.7 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4375) YojJ PF10372.9 KFM72217.1 - 0.01 15.9 1.8 0.042 13.9 0.5 2.4 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus Com_YlbF PF06133.11 KFM72217.1 - 0.02 15.5 0.9 0.036 14.7 0.9 1.5 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA IFN-gamma PF00714.17 KFM72217.1 - 0.026 14.4 0.6 0.043 13.7 0.6 1.3 1 0 0 1 1 1 0 Interferon gamma HTH_Tnp_Tc3_2 PF01498.18 KFM72218.1 - 2.2e-19 69.4 3.6 5.7e-19 68.1 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72218.1 - 4.9e-16 58.8 0.0 2.3e-15 56.6 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM72218.1 - 2.1e-07 30.9 0.4 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM72218.1 - 3.5e-07 30.7 4.4 3.6e-07 30.7 2.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72218.1 - 9.4e-07 28.9 2.3 7.6e-05 22.8 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72218.1 - 2e-06 27.5 3.4 2.5e-05 23.9 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM72218.1 - 2.8e-06 27.2 0.7 4e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM72218.1 - 0.00011 22.0 0.6 0.0017 18.2 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM72218.1 - 0.0012 18.8 0.3 0.016 15.1 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM72218.1 - 0.021 14.4 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM72218.1 - 0.062 13.4 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM72218.1 - 0.089 13.0 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM72218.1 - 0.16 11.5 0.2 0.81 9.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM72218.1 - 0.17 12.0 0.0 30 4.8 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM72218.1 - 0.3 10.9 3.9 1.4 8.7 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM72218.1 - 1.1 8.7 3.6 7.1 6.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HLH PF00010.26 KFM72219.1 - 2.7e-17 62.5 0.0 5.8e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Geminin PF07412.12 KFM72219.1 - 0.0071 16.1 1.2 0.013 15.3 1.2 1.4 1 0 0 1 1 1 1 Geminin PEP-utilisers_N PF05524.13 KFM72219.1 - 0.044 13.9 0.3 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal UPF0242 PF06785.11 KFM72219.1 - 0.054 13.6 0.5 0.071 13.2 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 KFM72219.1 - 0.36 11.1 2.8 1.2 9.4 2.6 1.9 1 1 0 1 1 1 0 Homeobox associated leucine zipper Zn_ribbon_recom PF13408.6 KFM72220.1 - 0.0001 22.7 3.1 0.00015 22.2 3.1 1.2 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain HNH_5 PF14279.6 KFM72220.1 - 0.055 13.3 0.4 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease DUF2797 PF10977.8 KFM72220.1 - 0.082 12.8 0.2 0.087 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Fe_hyd_SSU PF02256.17 KFM72221.1 - 0.019 15.1 0.3 0.044 13.9 0.3 1.6 1 0 0 1 1 1 0 Iron hydrogenase small subunit SET PF00856.28 KFM72222.1 - 7.9e-10 39.4 0.2 1.2e-09 38.7 0.2 1.3 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFM72223.1 - 1.5e-05 24.9 19.8 1.5e-05 24.9 19.8 2.1 2 0 0 2 2 2 1 MYND finger adh_short PF00106.25 KFM72224.1 - 5.6e-29 101.0 0.1 8.8e-29 100.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM72224.1 - 7.8e-18 64.9 0.0 1.3e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM72224.1 - 0.00021 21.3 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFM72224.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding DDE_3 PF13358.6 KFM72225.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72226.1 - 2.5e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72226.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PITH PF06201.13 KFM72227.1 - 3.8e-39 134.3 0.4 5.4e-39 133.8 0.4 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KFM72227.1 - 2e-27 95.2 0.1 3.3e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM72227.1 - 3.2e-05 24.3 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KFM72227.1 - 0.0001 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFM72227.1 - 0.00021 21.6 0.0 0.00058 20.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KFM72227.1 - 0.00041 19.8 0.0 0.0009 18.7 0.0 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFM72227.1 - 0.0034 17.3 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KFM72227.1 - 0.0054 16.5 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 KFM72227.1 - 0.0095 16.1 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KFM72227.1 - 0.043 13.6 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Dis3l2_C_term PF17877.1 KFM72227.1 - 0.15 12.4 0.0 1.4 9.3 0.0 2.2 1 1 1 2 2 2 0 DIS3-like exonuclease 2 C terminal DUF953 PF06110.11 KFM72227.1 - 0.15 11.7 0.0 0.83 9.3 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) LIM PF00412.22 KFM72228.1 - 2.2e-12 47.0 6.1 2.8e-12 46.7 6.1 1.2 1 0 0 1 1 1 1 LIM domain zf_UBZ PF18439.1 KFM72228.1 - 0.0075 15.8 6.6 0.13 11.9 2.4 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DNA_RNApol_7kD PF03604.13 KFM72228.1 - 0.19 11.5 6.1 1.3 8.7 1.7 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf_C2H2_13 PF18508.1 KFM72228.1 - 0.2 11.2 4.3 1 9.0 0.2 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-RanBP PF00641.18 KFM72228.1 - 0.21 10.9 5.6 1 8.7 1.7 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF3725 PF12523.8 KFM72228.1 - 1.3 9.4 4.2 9.9 6.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) HypA PF01155.19 KFM72228.1 - 2.3 8.2 5.0 0.63 10.1 0.6 1.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KFM72228.1 - 2.4 8.0 11.4 3.8 7.4 0.6 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2 PF00096.26 KFM72228.1 - 2.7 8.6 7.9 8.4 7.1 0.5 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type RA PF00788.23 KFM72229.1 - 3.3e-08 34.1 0.0 6.9e-08 33.0 0.0 1.5 1 1 1 2 2 2 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 KFM72229.1 - 0.0021 17.9 3.3 0.0035 17.2 3.3 1.4 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Fasciclin PF02469.22 KFM72230.1 - 6.1e-11 42.7 0.0 4.1e-06 27.0 0.0 2.5 2 1 0 2 2 2 2 Fasciclin domain HTH_Tnp_Tc3_2 PF01498.18 KFM72232.1 - 2.6e-16 59.6 2.2 4.9e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72232.1 - 1.1e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ABC2_membrane_3 PF12698.7 KFM72236.1 - 1.8e-13 50.4 5.4 1.9e-13 50.3 5.4 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein Ferlin_C PF16165.5 KFM72236.1 - 6.5 6.7 5.9 6.6 6.7 5.4 1.3 1 1 0 1 1 1 0 Ferlin C-terminus DUF397 PF04149.12 KFM72237.1 - 0.035 14.2 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF397) ABC_tran PF00005.27 KFM72238.1 - 2.1e-31 109.2 0.1 3.3e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM72238.1 - 3.3e-12 46.8 0.4 1.7e-07 31.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFM72238.1 - 0.008 16.1 0.2 0.014 15.3 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KFM72238.1 - 0.016 15.8 3.1 0.031 14.8 3.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM72238.1 - 0.025 14.3 0.4 0.05 13.3 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KFM72238.1 - 0.026 14.3 0.1 0.052 13.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFM72238.1 - 0.045 13.5 0.0 0.22 11.2 0.2 1.9 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KFM72238.1 - 0.068 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.22 KFM72238.1 - 0.075 12.7 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 KFM72238.1 - 0.076 12.4 0.0 8.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 KFM72238.1 - 0.12 11.8 0.3 3.1 7.2 0.2 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KFM72239.1 - 0.0011 18.2 0.2 0.0019 17.4 0.2 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein DDE_3 PF13358.6 KFM72240.1 - 4.6e-13 49.1 0.0 6.6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72241.1 - 3e-14 53.0 1.0 5.8e-14 52.1 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72241.1 - 7.9e-14 51.6 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2 PF00096.26 KFM72242.1 - 1.7e-08 34.4 18.5 2.1e-05 24.7 0.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM72242.1 - 6.4e-06 26.4 14.3 1.7e-05 25.0 0.7 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM72242.1 - 0.00022 21.8 12.1 0.087 13.7 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFM72242.1 - 0.0034 18.0 5.0 0.51 11.0 0.3 2.6 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 KFM72243.1 - 5.9e-15 54.8 23.1 2.9e-05 24.3 0.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM72243.1 - 7.4e-12 45.1 24.1 1.4e-07 31.6 1.1 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM72243.1 - 8.6e-09 35.5 21.3 0.0021 18.8 3.0 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFM72243.1 - 0.0018 18.8 6.0 0.3 11.7 0.1 3.0 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KFM72243.1 - 0.026 14.3 2.7 1.5 8.7 1.0 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM72243.1 - 0.13 12.6 4.8 2.8 8.3 1.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM72243.1 - 0.3 11.5 6.5 5.8 7.5 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KFM72243.1 - 0.94 10.2 4.8 0.62 10.8 1.0 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_8 PF15909.5 KFM72243.1 - 2.1 8.7 9.9 0.22 11.9 4.9 2.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon Jnk-SapK_ap_N PF09744.9 KFM72244.1 - 1.5e-54 184.4 22.0 1.5e-54 184.4 22.0 4.8 5 1 1 6 6 6 1 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 KFM72244.1 - 1.2e-30 105.5 11.4 1.2e-30 105.5 11.4 4.7 3 1 1 4 4 4 1 JNK-interacting protein leucine zipper II RILP PF11461.8 KFM72244.1 - 0.0049 17.1 17.1 0.039 14.2 0.1 3.7 3 0 0 3 3 3 2 Rab interacting lysosomal protein TAP35_44 PF07265.11 KFM72244.1 - 0.04 13.9 0.2 0.27 11.3 0.2 2.4 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 DUF1974 PF09317.11 KFM72244.1 - 0.24 10.9 12.2 1.1 8.8 4.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) DUF5365 PF17326.2 KFM72244.1 - 0.24 11.8 3.5 1.2 9.6 3.2 2.5 1 1 0 1 1 1 0 Family of unknown function (DUF5365) WD40_alt PF14077.6 KFM72244.1 - 0.34 10.8 3.3 0.41 10.5 0.7 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif SseC PF04888.12 KFM72244.1 - 0.59 9.7 4.2 1.1 8.8 2.4 2.3 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF1759 PF03564.15 KFM72244.1 - 1.1 9.2 11.3 0.032 14.1 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Pox_A_type_inc PF04508.12 KFM72244.1 - 2 8.4 5.0 4.4 7.3 3.3 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat THAP PF05485.12 KFM72245.1 - 2.4e-12 47.6 0.8 2.7e-12 47.4 0.8 1.0 1 0 0 1 1 1 1 THAP domain Nop14 PF04147.12 KFM72246.1 - 3.2e-119 399.6 39.5 9.1e-78 262.4 25.1 2.0 1 1 1 2 2 2 2 Nop14-like family Nop14 PF04147.12 KFM72247.1 - 1.6e-22 79.6 8.4 1.7e-22 79.6 8.4 1.0 1 0 0 1 1 1 1 Nop14-like family DAG1 PF05454.11 KFM72247.1 - 0.011 15.1 0.8 0.012 15.0 0.8 1.0 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) P66_CC PF16563.5 KFM72247.1 - 0.21 11.2 10.7 0.79 9.4 0.7 2.4 2 0 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Pribosyltran_N PF13793.6 KFM72248.1 - 2.7e-48 162.7 0.6 1.3e-47 160.6 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFM72248.1 - 2.4e-41 141.8 0.5 5.9e-34 117.7 0.1 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFM72248.1 - 7.4e-15 54.8 1.2 1.9e-14 53.5 0.2 2.1 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFM72248.1 - 0.00011 21.7 0.1 0.00021 20.8 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase zf-C2H2_6 PF13912.6 KFM72250.1 - 2.2e-07 30.7 10.3 0.00043 20.2 0.6 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM72250.1 - 3e-07 30.5 8.5 0.0035 17.7 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72250.1 - 5.1e-06 26.9 10.1 0.0061 17.3 0.2 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFM72250.1 - 0.00029 20.4 3.2 0.016 14.8 0.3 2.1 2 0 0 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KFM72250.1 - 0.00038 20.7 2.0 0.0079 16.5 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFM72250.1 - 0.00039 20.0 1.1 0.33 10.6 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger ArfGap PF01412.18 KFM72250.1 - 0.012 15.6 2.3 0.13 12.4 0.3 2.0 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf ADK_lid PF05191.14 KFM72250.1 - 0.047 13.7 3.1 0.21 11.6 3.1 1.9 1 1 1 2 2 2 0 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KFM72250.1 - 3.4 7.5 10.1 2.8 7.8 3.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain TUDOR PF00567.24 KFM72251.1 - 2.7e-101 334.1 7.6 2.8e-28 98.4 0.0 5.5 5 0 0 5 5 5 5 Tudor domain Agenet PF05641.12 KFM72251.1 - 2.4e-09 37.5 1.3 0.035 14.6 0.0 4.4 4 0 0 4 4 4 3 Agenet domain SMN PF06003.12 KFM72251.1 - 0.00016 21.1 0.0 0.014 14.6 0.0 3.3 3 0 0 3 3 3 1 Survival motor neuron protein (SMN) DUF4537 PF15057.6 KFM72251.1 - 0.00023 21.2 0.2 0.42 10.7 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4537) SNase PF00565.17 KFM72251.1 - 0.003 18.0 0.0 0.75 10.3 0.0 3.4 3 0 0 3 3 3 1 Staphylococcal nuclease homologue DUF1325 PF07039.11 KFM72251.1 - 0.023 14.8 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 0 SGF29 tudor-like domain DUF1462 PF07315.11 KFM72251.1 - 0.057 13.7 0.0 2.8 8.3 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1462) LBR_tudor PF09465.10 KFM72251.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.9 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain TUDOR PF00567.24 KFM72252.1 - 3.4e-18 65.8 0.1 5.3e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 KFM72252.1 - 0.0013 19.2 0.2 0.03 14.8 0.1 2.2 2 0 0 2 2 2 1 Agenet domain SMN PF06003.12 KFM72252.1 - 0.048 12.9 0.1 0.066 12.5 0.1 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) FMN_dh PF01070.18 KFM72253.1 - 1.3e-138 461.8 0.0 1.5e-138 461.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFM72253.1 - 3.3e-06 26.4 1.0 6.6e-06 25.3 0.9 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFM72253.1 - 1.1e-05 24.8 0.3 1.7e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KFM72253.1 - 0.0029 16.9 2.2 0.25 10.6 0.4 2.4 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KFM72253.1 - 0.0041 16.6 0.1 0.013 15.0 0.0 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 KFM72253.1 - 0.028 13.8 0.1 6.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 KFM72253.1 - 0.11 11.9 0.4 0.16 11.3 0.4 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase N_Asn_amidohyd PF14736.6 KFM72254.1 - 6.6e-116 386.2 0.0 7.6e-116 386.0 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase Sema PF01403.19 KFM72255.1 - 4e-127 424.6 0.8 5e-127 424.2 0.8 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFM72255.1 - 2.3e-08 34.4 6.0 6.4e-08 33.0 6.0 1.8 1 0 0 1 1 1 1 Plexin repeat HTH_Tnp_Tc3_2 PF01498.18 KFM72256.1 - 2e-16 60.0 4.3 4.8e-16 58.7 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72256.1 - 5.9e-14 52.0 0.0 1.8e-13 50.5 0.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease Aldolase_II PF00596.21 KFM72257.1 - 7e-39 133.7 0.3 3.7e-38 131.3 0.1 2.1 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM72258.1 - 1.7e-17 63.4 1.3 4e-17 62.2 1.3 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72258.1 - 1.1e-09 38.2 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM72258.1 - 1e-06 29.2 5.2 7.2e-06 26.5 1.9 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM72258.1 - 0.002 18.1 0.5 0.093 12.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix MarR_2 PF12802.7 KFM72258.1 - 0.01 15.7 0.2 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 MarR family HTH_28 PF13518.6 KFM72258.1 - 0.03 14.5 1.0 1.4 9.1 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM72258.1 - 0.034 14.1 1.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain PAX PF00292.18 KFM72258.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 1 0 1 1 1 0 'Paired box' domain HTH_26 PF13443.6 KFM72258.1 - 0.17 12.3 0.3 11 6.5 0.2 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 KFM72258.1 - 0.19 11.3 1.7 3.3 7.3 0.0 2.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM72258.1 - 0.4 10.5 4.3 2.7 7.9 0.1 3.2 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM72259.1 - 3e-14 53.0 1.0 6.7e-14 51.9 1.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72259.1 - 8.6e-14 51.5 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Tnp_P_element PF12017.8 KFM72260.1 - 6.3e-09 35.6 2.5 8.9e-09 35.1 2.5 1.3 1 0 0 1 1 1 1 Transposase protein DUF5082 PF16888.5 KFM72260.1 - 8.9e-05 22.8 0.5 0.00031 21.0 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) Exonuc_VII_L PF02601.15 KFM72260.1 - 0.0078 15.8 0.6 0.0088 15.6 0.6 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Imm6 PF14434.6 KFM72260.1 - 0.071 13.0 2.0 0.13 12.2 2.0 1.5 1 0 0 1 1 1 0 Immunity protein Imm6 YtxH PF12732.7 KFM72260.1 - 0.29 11.7 1.3 7.1 7.2 1.3 2.6 1 1 0 1 1 1 0 YtxH-like protein FeoA PF04023.14 KFM72261.1 - 0.012 15.8 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 FeoA domain Rhodanese PF00581.20 KFM72262.1 - 1.8e-06 28.4 0.0 3.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain RabGAP-TBC PF00566.18 KFM72262.1 - 0.0023 17.6 0.1 0.0033 17.1 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 KFM72264.1 - 1.2e-06 28.2 0.1 1.8e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0051 PF01458.17 KFM72264.1 - 0.095 12.4 1.8 0.12 12.1 1.7 1.3 1 1 0 1 1 1 0 Uncharacterized protein family (UPF0051) RRM_5 PF13893.6 KFM72264.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RR_TM4-6 PF06459.12 KFM72264.1 - 9.7 5.9 10.5 11 5.7 10.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 KFM72265.1 - 1.3e-47 159.5 1.9 4.9e-22 77.5 0.2 3.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM72265.1 - 1.9e-07 30.9 4.6 0.076 13.0 0.1 4.6 5 0 0 5 5 5 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFM72265.1 - 4e-06 26.8 6.0 0.0038 17.2 0.3 3.4 2 1 1 3 3 3 2 RNA binding motif RRM_7 PF16367.5 KFM72265.1 - 2.1e-05 24.5 0.2 0.16 12.1 0.0 3.9 3 1 0 3 3 3 1 RNA recognition motif RNA_bind PF08675.11 KFM72265.1 - 0.00015 21.7 1.9 0.23 11.5 0.3 3.6 2 1 1 3 3 3 2 RNA binding domain RRM_occluded PF16842.5 KFM72265.1 - 0.00021 21.1 0.3 0.0031 17.4 0.0 2.7 3 1 0 3 3 3 1 Occluded RNA-recognition motif BRAP2 PF07576.12 KFM72265.1 - 0.0077 16.4 0.8 0.33 11.2 0.1 2.5 2 1 0 2 2 2 1 BRCA1-associated protein 2 Limkain-b1 PF11608.8 KFM72265.1 - 0.028 14.5 0.3 0.78 9.9 0.0 3.0 3 1 0 3 3 3 0 Limkain b1 PHM7_cyt PF14703.6 KFM72265.1 - 0.037 14.3 5.6 0.71 10.1 2.7 3.7 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter GNAT_acetyltran PF12746.7 KFM72265.1 - 0.41 10.2 3.5 1.6 8.2 0.8 2.3 2 1 0 2 2 2 0 GNAT acetyltransferase Bac_DNA_binding PF00216.21 KFM72265.1 - 0.64 10.3 4.0 0.25 11.5 0.3 2.2 2 1 1 3 3 3 0 Bacterial DNA-binding protein Claudin_2 PF13903.6 KFM72266.1 - 5e-34 117.8 0.6 6.4e-34 117.4 0.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFM72266.1 - 1.1e-05 25.4 8.9 0.00012 22.0 8.4 2.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 KFM72266.1 - 0.27 10.8 11.1 0.2 11.3 6.9 2.5 2 1 0 2 2 2 0 SUR7/PalI family Ank_4 PF13637.6 KFM72269.1 - 8.5e-47 157.0 5.4 4.8e-12 46.1 0.0 6.4 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM72269.1 - 3.3e-42 143.0 17.6 4.3e-13 49.7 1.7 5.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KFM72269.1 - 7.3e-38 127.4 11.1 6.8e-08 32.6 0.1 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 KFM72269.1 - 9e-36 117.9 9.7 5.3e-06 26.4 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFM72269.1 - 3.7e-34 116.3 10.7 5e-12 45.8 0.1 6.9 5 1 1 6 6 6 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFM72269.1 - 0.00032 21.0 0.4 0.00087 19.6 0.4 1.9 1 0 0 1 1 1 1 SOCS box Glyco_transf_92 PF01697.27 KFM72270.1 - 6.1e-55 186.7 2.2 9.2e-55 186.1 2.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFM72270.1 - 4e-06 27.3 0.3 1.6e-05 25.4 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 HECT PF00632.25 KFM72271.1 - 5e-103 344.8 0.0 5.7e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HTH_Tnp_Tc3_2 PF01498.18 KFM72272.1 - 5.6e-16 58.5 2.2 5.6e-16 58.5 2.2 2.0 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM72272.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72272.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72272.1 - 0.0027 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72272.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM72273.1 - 1.9e-13 50.5 6.5 2.5e-13 50.1 5.2 1.8 1 1 1 2 2 2 1 Transposase HTH_12 PF08461.10 KFM72273.1 - 0.046 13.7 0.3 0.08 12.9 0.3 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_32 PF13565.6 KFM72273.1 - 0.053 14.1 1.5 0.053 14.1 1.5 2.2 1 1 1 2 2 2 0 Homeodomain-like domain Rap1a PF18602.1 KFM72273.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Rap1a immunity proteins HTH_Tnp_Tc3_2 PF01498.18 KFM72274.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72274.1 - 9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72276.1 - 2.4e-16 59.7 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72276.1 - 9.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease I-set PF07679.16 KFM72277.1 - 1.1e-21 76.7 0.0 1.4e-12 47.5 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM72277.1 - 4.7e-19 68.3 0.1 2.4e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFM72277.1 - 9.8e-18 64.5 0.0 9.4e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM72277.1 - 2.6e-13 50.1 1.9 0.00013 22.1 0.0 3.0 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM72277.1 - 4.3e-12 46.2 0.1 9.7e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFM72277.1 - 9e-08 31.6 0.0 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 KFM72277.1 - 3.7e-07 30.5 0.0 0.0031 17.9 0.0 2.1 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Herpes_gE PF02480.16 KFM72277.1 - 1.7e-05 23.7 0.1 0.011 14.6 0.0 2.0 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.8 KFM72277.1 - 0.0028 17.8 0.1 0.041 14.1 0.0 2.2 2 1 0 2 2 2 1 Natural killer cell receptor 2B4 Ig_4 PF16680.5 KFM72277.1 - 0.0034 17.6 0.1 0.41 10.9 0.0 2.4 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 KFM72277.1 - 0.0077 16.4 0.0 0.063 13.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 KFM72277.1 - 0.0093 16.0 0.0 2.5 8.2 0.0 2.3 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain F-box-like PF12937.7 KFM72278.1 - 1.4e-12 47.3 0.5 3.4e-12 46.0 0.5 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFM72278.1 - 6.3e-11 42.3 8.7 0.004 17.5 0.0 5.5 4 2 1 6 6 6 3 Leucine Rich repeats (2 copies) F-box PF00646.33 KFM72278.1 - 8e-07 28.8 0.7 3.4e-06 26.8 0.1 2.4 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 KFM72278.1 - 5.7e-05 22.8 1.5 0.036 13.8 0.0 4.1 3 1 3 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 KFM72278.1 - 0.0002 21.4 4.2 50 5.0 0.0 6.7 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 KFM72278.1 - 0.00045 20.0 7.3 11 6.3 0.1 5.9 6 0 0 6 6 6 2 Leucine Rich repeat TRAPPC-Trs85 PF12739.7 KFM72279.1 - 8.6e-122 407.0 0.8 1.3e-121 406.5 0.8 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.6 KFM72279.1 - 0.0024 17.3 0.2 0.0024 17.3 0.2 2.3 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP EGF PF00008.27 KFM72280.1 - 6.4e-06 26.4 5.1 6.4e-06 26.4 5.1 1.6 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 KFM72280.1 - 0.00012 22.5 2.2 0.0003 21.3 0.7 2.2 2 1 0 2 2 2 1 Human growth factor-like EGF I-set PF07679.16 KFM72280.1 - 0.0037 17.3 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain EGF_2 PF07974.13 KFM72280.1 - 0.015 15.6 1.3 0.031 14.6 1.3 1.6 1 1 0 1 1 1 0 EGF-like domain TruD PF01142.18 KFM72282.1 - 4.9e-73 246.3 0.0 1.1e-68 232.1 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF3091 PF11291.8 KFM72282.1 - 0.0054 16.9 1.6 0.16 12.2 0.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3091) DUF1616 PF07760.11 KFM72282.1 - 0.15 11.4 0.9 0.25 10.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Laminin_N PF00055.17 KFM72283.1 - 5.1e-06 26.3 0.0 6.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) zf-RING_2 PF13639.6 KFM72284.1 - 7.5e-12 45.4 4.5 1.3e-11 44.7 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFM72284.1 - 9.2e-10 38.1 3.0 9.2e-10 38.1 3.0 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFM72284.1 - 2e-07 30.7 4.1 3.3e-07 30.0 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM72284.1 - 5.9e-07 29.4 2.4 1.3e-06 28.3 2.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM72284.1 - 2.5e-06 27.3 2.3 2.5e-06 27.3 2.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM72284.1 - 4.5e-05 23.2 1.3 4.5e-05 23.2 1.3 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM72284.1 - 9.9e-05 22.2 1.9 0.00025 20.9 1.9 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KFM72284.1 - 0.00011 21.8 2.3 0.0002 20.9 2.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KFM72284.1 - 0.00012 22.2 9.3 0.001 19.3 9.3 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain FANCL_C PF11793.8 KFM72284.1 - 0.037 14.2 6.4 0.53 10.5 6.4 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain QueC PF06508.13 KFM72284.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Prok-RING_4 PF14447.6 KFM72284.1 - 0.15 12.0 6.5 0.12 12.2 4.0 2.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KFM72284.1 - 0.27 11.3 5.2 0.69 10.0 5.2 1.8 1 1 0 1 1 1 0 Zinc-finger zf-ANAPC11 PF12861.7 KFM72284.1 - 1.2 9.2 6.1 7.9 6.6 6.1 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger adh_short PF00106.25 KFM72285.1 - 7.2e-26 90.9 0.0 8.6e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM72285.1 - 1.6e-15 57.3 0.0 2.2e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM72285.1 - 1.1e-06 28.7 0.0 1.2e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Hpr_kinase_C PF07475.12 KFM72285.1 - 0.0013 18.3 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain DDE_3 PF13358.6 KFM72286.1 - 5.1e-16 58.7 0.1 5.8e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72286.1 - 7.7e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72286.1 - 0.00093 19.8 1.0 0.00093 19.8 1.0 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72286.1 - 0.0025 17.6 0.1 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72286.1 - 0.016 15.3 0.1 0.064 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM72286.1 - 0.018 15.1 1.5 0.036 14.1 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix FAM181 PF15238.6 KFM72287.1 - 9.5e-07 28.9 0.2 9.5e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 FAM181 GYF_2 PF14237.6 KFM72288.1 - 3.4e-19 68.4 0.3 7e-19 67.4 0.3 1.6 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 KFM72288.1 - 3.5e-15 55.9 0.1 3.5e-15 55.9 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain Arm PF00514.23 KFM72288.1 - 0.015 15.3 6.2 0.084 13.0 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DDE_3 PF13358.6 KFM72290.1 - 1e-11 44.8 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72291.1 - 2.1e-16 59.9 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72291.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72292.1 - 1.1e-16 60.8 2.6 2.8e-16 59.5 1.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72292.1 - 8.4e-16 58.0 0.0 2e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM72292.1 - 5e-07 29.3 0.5 2e-05 24.3 0.0 2.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72292.1 - 5.9e-07 30.0 1.7 5.9e-07 30.0 1.7 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KFM72292.1 - 2.5e-06 27.5 0.9 0.0011 19.0 0.1 2.8 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM72292.1 - 8.2e-06 25.8 0.4 0.00014 21.8 0.1 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM72292.1 - 2.7e-05 24.2 1.9 0.0026 17.8 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KFM72292.1 - 0.00037 20.3 0.4 0.0029 17.4 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM72292.1 - 0.0022 17.9 0.8 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_22 PF13309.6 KFM72292.1 - 0.087 12.9 0.0 19 5.4 0.0 2.5 2 0 0 2 2 2 0 HTH domain GntR PF00392.21 KFM72292.1 - 0.089 12.5 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_30 PF13556.6 KFM72292.1 - 0.49 10.2 3.2 4.2 7.3 0.0 3.1 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM72293.1 - 2.4e-16 59.7 2.2 4.3e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72293.1 - 2.5e-13 50.0 0.0 4.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72294.1 - 2.4e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72294.1 - 5.4e-13 48.9 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72295.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72295.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72295.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72295.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72295.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ABC_membrane PF00664.23 KFM72296.1 - 2.4e-58 197.9 5.4 3.2e-58 197.5 5.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFM72296.1 - 2.6e-34 118.7 0.0 5.7e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM72296.1 - 2.2e-08 33.8 0.6 3.6e-07 29.9 0.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KFM72296.1 - 9.6e-05 21.4 0.0 0.00028 19.8 0.0 1.7 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 KFM72296.1 - 0.0015 18.9 0.3 0.014 15.6 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM72296.1 - 0.003 18.0 0.2 0.015 15.7 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFM72296.1 - 0.0064 16.4 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 KFM72296.1 - 0.017 14.4 0.2 0.043 13.1 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin G-alpha PF00503.20 KFM72296.1 - 0.024 13.8 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit SbcCD_C PF13558.6 KFM72296.1 - 0.028 14.6 0.6 0.31 11.3 0.6 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KFM72296.1 - 0.032 13.9 0.1 0.17 11.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFM72296.1 - 0.037 14.4 0.1 0.64 10.5 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KFM72296.1 - 0.056 13.1 0.0 0.056 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 KFM72296.1 - 0.069 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KFM72296.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KFM72296.1 - 0.12 12.4 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KFM72296.1 - 0.12 12.3 0.0 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 KFM72296.1 - 0.12 12.7 0.1 3 8.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 KFM72296.1 - 0.17 11.7 0.1 0.5 10.1 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 KFM72297.1 - 5.3e-120 400.2 28.0 1.6e-64 218.2 9.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFM72297.1 - 1.2e-73 246.0 5.0 3.3e-36 124.8 0.0 3.3 4 0 0 4 4 2 2 ABC transporter SMC_N PF02463.19 KFM72297.1 - 4.1e-17 62.4 2.6 1.3e-07 31.3 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFM72297.1 - 4.7e-10 40.1 4.1 0.00019 21.9 0.1 3.6 4 0 0 4 4 3 2 AAA ATPase domain ABC_ATPase PF09818.9 KFM72297.1 - 7.2e-09 34.9 1.0 0.00025 20.0 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KFM72297.1 - 5e-08 33.3 0.7 0.03 14.6 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFM72297.1 - 7.1e-08 32.1 1.5 0.06 13.1 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM72297.1 - 8.3e-08 32.3 0.1 0.011 15.7 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 KFM72297.1 - 2.5e-07 30.8 0.0 0.0084 16.0 0.0 3.0 3 0 0 3 3 3 2 Rad17 P-loop domain AAA PF00004.29 KFM72297.1 - 3.6e-07 30.7 0.4 0.034 14.6 0.0 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM72297.1 - 2.7e-06 27.4 0.3 0.15 12.1 0.0 3.8 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KFM72297.1 - 3.1e-06 27.1 0.0 0.076 12.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KFM72297.1 - 4.5e-06 26.1 0.9 0.023 14.0 0.0 3.3 4 0 0 4 4 4 2 Zeta toxin AAA_30 PF13604.6 KFM72297.1 - 1.5e-05 24.8 1.4 0.31 10.7 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KFM72297.1 - 4.4e-05 23.4 0.0 0.11 12.3 0.0 3.7 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFM72297.1 - 4.8e-05 23.0 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KFM72297.1 - 0.00021 21.1 0.0 0.084 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFM72297.1 - 0.00026 21.2 0.1 1 9.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 KFM72297.1 - 0.00028 20.1 0.0 0.51 9.5 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF815) AAA_28 PF13521.6 KFM72297.1 - 0.00033 21.0 0.0 0.54 10.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain G-alpha PF00503.20 KFM72297.1 - 0.00052 19.3 0.1 0.1 11.8 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit APS_kinase PF01583.20 KFM72297.1 - 0.00065 19.6 0.1 0.44 10.4 0.0 2.7 3 0 0 3 3 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 KFM72297.1 - 0.0011 18.6 0.0 0.62 9.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain PRK PF00485.18 KFM72297.1 - 0.0011 18.7 0.4 1.5 8.5 0.0 3.0 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KFM72297.1 - 0.0014 17.9 0.4 0.97 8.6 0.0 2.6 3 0 0 3 3 2 2 NB-ARC domain RNA_helicase PF00910.22 KFM72297.1 - 0.0016 18.8 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 KFM72297.1 - 0.0018 18.3 0.4 6.4 6.8 0.0 4.2 5 0 0 5 5 4 0 AAA domain NACHT PF05729.12 KFM72297.1 - 0.0057 16.6 0.2 4.5 7.2 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 KFM72297.1 - 0.0059 17.2 0.0 1.9 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFM72297.1 - 0.0095 16.5 1.0 2.3 8.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KFM72297.1 - 0.018 15.1 0.0 3.3 7.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KFM72297.1 - 0.02 14.6 1.6 8.2 6.1 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KFM72297.1 - 0.021 14.6 0.1 3.8 7.2 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.6 KFM72297.1 - 0.023 15.0 10.3 0.69 10.2 0.3 4.4 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KFM72297.1 - 0.031 13.9 0.1 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 KFM72297.1 - 0.034 14.5 0.1 5.7 7.3 0.1 3.1 2 1 0 2 2 2 0 AAA domain MoaE PF02391.17 KFM72297.1 - 0.043 14.1 0.5 3.2 8.0 0.1 2.7 2 0 0 2 2 2 0 MoaE protein NTPase_1 PF03266.15 KFM72297.1 - 0.055 13.4 0.1 6.5 6.6 0.0 2.9 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 KFM72297.1 - 0.11 12.5 1.9 5.6 7.0 0.0 3.2 4 0 0 4 4 2 0 Helicase HerA, central domain TsaE PF02367.17 KFM72297.1 - 0.12 12.4 0.1 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4191 PF13829.6 KFM72297.1 - 0.56 9.5 3.0 1.8 7.9 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) RNase_H PF00075.24 KFM72299.1 - 3e-06 27.5 0.0 4.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 RNase H Pkinase PF00069.25 KFM72301.1 - 1.1e-17 64.3 0.1 1.2e-17 64.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM72301.1 - 2.2e-11 43.6 0.0 2.3e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCHC_4 PF14392.6 KFM72302.1 - 0.42 10.4 15.1 0.41 10.4 1.7 2.7 3 0 0 3 3 3 0 Zinc knuckle LRRNT PF01462.18 KFM72304.1 - 0.00085 18.9 2.9 0.0013 18.4 2.9 1.3 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Toxin_11 PF07473.11 KFM72304.1 - 0.043 13.9 1.5 0.072 13.2 1.5 1.4 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species DDE_3 PF13358.6 KFM72305.1 - 4e-11 42.9 0.0 7e-11 42.1 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-Tim10_DDP PF02953.15 KFM72307.1 - 6e-24 83.5 1.2 7.7e-24 83.1 1.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF543 PF04418.12 KFM72307.1 - 0.13 12.3 1.2 4.2 7.4 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF543) DDE_Tnp_1_7 PF13843.6 KFM72308.1 - 9.1e-35 120.6 0.3 8e-34 117.5 0.3 1.9 1 1 0 1 1 1 1 Transposase IS4 P53 PF00870.18 KFM72309.1 - 3.2e-59 200.0 0.1 4.1e-59 199.6 0.1 1.1 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.11 KFM72309.1 - 0.0033 16.7 3.9 0.0033 16.7 3.9 1.8 2 0 0 2 2 2 1 P53 tetramerisation motif Laminin_II PF06009.12 KFM72311.1 - 0.011 15.8 0.4 0.013 15.6 0.4 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF16 PF01519.16 KFM72312.1 - 0.0073 16.8 1.3 0.79 10.2 1.3 2.4 1 1 0 1 1 1 1 Protein of unknown function DUF16 Vac14_Fab1_bd PF12755.7 KFM72312.1 - 0.098 13.3 1.2 2.1 9.0 0.0 2.7 2 2 1 3 3 3 0 Vacuolar 14 Fab1-binding region DEAD PF00270.29 KFM72313.1 - 3.3e-24 85.6 0.1 6.4e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM72313.1 - 2.1e-10 40.9 0.2 1.8e-09 37.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain rve PF00665.26 KFM72314.1 - 4.5e-05 23.6 0.0 4.5e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain FERM_M PF00373.18 KFM72315.1 - 2e-13 50.8 0.0 3e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 FERM central domain FERM_N PF09379.10 KFM72315.1 - 7.8e-13 48.2 0.0 2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain zf-C3HC4_3 PF13920.6 KFM72315.1 - 6.5e-09 35.5 18.3 6.5e-09 35.5 18.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FERM_C PF09380.10 KFM72315.1 - 0.00011 22.5 0.0 0.00038 20.8 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Prok-RING_4 PF14447.6 KFM72315.1 - 0.53 10.2 19.6 2 8.3 19.6 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFM72316.1 - 2.4e-11 43.3 5.9 4.1e-11 42.6 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM72316.1 - 1e-05 25.3 7.5 2.1e-05 24.3 7.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFM72316.1 - 0.00016 21.9 9.6 0.00035 20.8 9.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM72316.1 - 0.0018 18.2 8.2 0.0018 18.2 8.2 1.7 2 0 0 2 2 2 1 zinc-RING finger domain Cript PF10235.9 KFM72316.1 - 0.018 15.6 3.7 0.036 14.6 3.7 1.6 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT DUF2039 PF10217.9 KFM72316.1 - 0.074 13.4 3.7 0.11 12.9 3.7 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_UBOX PF13445.6 KFM72316.1 - 0.42 10.7 7.3 2.9 8.0 7.3 2.3 1 1 0 1 1 1 0 RING-type zinc-finger Zn-C2H2_12 PF18112.1 KFM72316.1 - 1.2 9.7 6.6 12 6.4 0.8 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain SPRY PF00622.28 KFM72317.1 - 9.3e-07 29.0 0.6 1.3e-06 28.5 0.6 1.2 1 0 0 1 1 1 1 SPRY domain DUF2214 PF09980.9 KFM72317.1 - 0.034 14.0 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) Ntox17 PF15524.6 KFM72317.1 - 0.082 13.2 0.1 0.17 12.2 0.0 1.5 2 0 0 2 2 2 0 Novel toxin 17 Coilin_N PF15862.5 KFM72319.1 - 0.15 11.9 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus rve PF00665.26 KFM72322.1 - 2.6e-21 76.0 0.1 3.9e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM72322.1 - 2.1e-11 43.7 0.6 4.2e-11 42.8 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_IS240 PF13610.6 KFM72322.1 - 6.5e-05 23.2 0.6 0.00011 22.4 0.6 1.4 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 KFM72322.1 - 7.4e-05 22.4 0.6 0.0052 16.5 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFM72322.1 - 0.0021 18.2 0.1 0.0057 16.8 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DDE_3 PF13358.6 KFM72322.1 - 0.013 15.2 0.2 0.021 14.6 0.2 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease ATG11 PF10377.9 KFM72322.1 - 0.098 12.7 0.5 4.7 7.3 0.1 2.3 2 0 0 2 2 2 0 Autophagy-related protein 11 tRNA-synt_1b PF00579.25 KFM72324.1 - 9.7e-08 31.7 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF4817 PF16087.5 KFM72325.1 - 6.7e-11 41.8 0.2 1.2e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 KFM72325.1 - 0.00051 20.6 0.4 0.00081 20.0 0.4 1.3 1 0 0 1 1 1 1 Homeodomain-like domain DUF772 PF05598.11 KFM72325.1 - 0.096 12.7 0.2 9.3 6.3 0.0 2.5 2 1 0 2 2 2 0 Transposase domain (DUF772) HTH_23 PF13384.6 KFM72325.1 - 0.31 10.9 2.6 24 4.9 0.1 2.9 3 0 0 3 3 3 0 Homeodomain-like domain FKBP_C PF00254.28 KFM72327.1 - 4.8e-34 116.6 0.0 3.8e-24 84.8 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 KFM72327.1 - 6.3e-11 41.5 1.5 0.00045 20.1 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM72327.1 - 5.5e-09 35.5 2.4 0.00026 20.7 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM72327.1 - 3.8e-06 26.7 1.6 0.0047 17.0 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM72327.1 - 0.00016 21.7 0.0 0.005 17.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM72327.1 - 0.00021 21.9 0.0 0.19 12.7 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM72327.1 - 0.0021 17.7 0.0 0.018 14.7 0.0 2.4 1 1 1 2 2 2 1 TPR repeat Fis1_TPR_C PF14853.6 KFM72327.1 - 0.0064 16.5 0.1 0.098 12.7 0.1 2.6 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 KFM72327.1 - 0.031 14.7 0.3 0.39 11.2 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM72327.1 - 0.039 14.6 0.1 4.4 8.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM72327.1 - 0.042 14.1 0.1 2.9 8.2 0.3 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM72327.1 - 0.075 13.6 0.3 0.17 12.4 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM72327.1 - 0.14 12.2 0.1 1.1 9.4 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM72327.1 - 0.15 12.8 0.0 37 5.1 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM72327.1 - 0.28 11.4 1.8 1.2 9.5 0.9 2.1 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TMEM169 PF15052.6 KFM72328.1 - 1.6e-21 76.8 0.8 2.3e-21 76.3 0.8 1.2 1 0 0 1 1 1 1 TMEM169 protein family HTH_Tnp_Tc3_2 PF01498.18 KFM72329.1 - 1.5e-17 63.6 1.6 5.1e-16 58.7 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72329.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_1 PF00001.21 KFM72330.1 - 5.4e-13 48.9 2.6 5.8e-13 48.8 2.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM72330.1 - 0.00017 21.3 0.2 0.00019 21.2 0.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFM72330.1 - 0.00084 18.8 1.5 0.00095 18.6 1.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFM72330.1 - 0.0023 17.7 0.1 0.0025 17.6 0.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFM72331.1 - 5.4e-14 52.1 0.3 6.6e-14 51.9 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFM72331.1 - 0.0013 18.1 1.0 0.0017 17.7 1.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Peptidase_C12 PF01088.21 KFM72334.1 - 1.1e-26 93.9 0.1 1.2e-26 93.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DDE_3 PF13358.6 KFM72335.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF659 PF04937.15 KFM72335.1 - 0.00023 21.0 0.2 0.00074 19.4 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM72335.1 - 0.00038 20.2 0.3 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) HTH_Tnp_Tc3_2 PF01498.18 KFM72336.1 - 2e-16 60.0 2.2 4.7e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72336.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Homeodomain PF00046.29 KFM72337.1 - 2.6e-61 203.3 19.0 3.9e-17 61.8 0.6 4.8 4 0 0 4 4 4 4 Homeodomain zf-C2H2 PF00096.26 KFM72337.1 - 6.3e-22 76.8 149.5 0.0071 16.7 0.7 22.6 24 0 0 24 24 24 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72337.1 - 1.8e-19 68.7 125.7 0.017 16.0 0.4 22.5 22 0 0 22 22 22 12 C2H2-type zinc finger Homeobox_KN PF05920.11 KFM72337.1 - 8.6e-13 48.0 1.2 0.0015 18.4 0.0 4.9 4 0 0 4 4 4 3 Homeobox KN domain zf-met PF12874.7 KFM72337.1 - 1.4e-06 28.4 103.6 0.00034 20.9 1.1 15.2 17 1 0 17 17 16 8 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM72337.1 - 3.2e-06 27.3 4.2 3.2e-06 27.3 4.2 13.5 14 2 2 16 16 15 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFM72337.1 - 0.00026 20.7 1.3 0.00026 20.7 1.3 10.7 12 0 0 12 12 11 4 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM72337.1 - 0.0029 17.9 132.4 0.17 12.2 3.0 20.8 15 5 7 22 22 21 7 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 KFM72337.1 - 0.24 11.6 0.0 0.24 11.6 0.0 12.8 14 1 1 15 15 14 0 A-kinase anchoring protein 95 (AKAP95) zf-Sec23_Sec24 PF04810.15 KFM72337.1 - 0.71 10.0 0.0 0.71 10.0 0.0 10.7 13 1 0 13 13 13 0 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM72337.1 - 1.7 8.7 27.7 15 5.6 0.3 8.5 8 0 0 8 8 7 0 Adenylate kinase, active site lid HTH_Tnp_Tc3_2 PF01498.18 KFM72339.1 - 2.6e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72339.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Tn7_TnsC_Int PF11426.8 KFM72340.1 - 0.2 11.9 1.0 0.28 11.4 1.0 1.2 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC Glyco_transf_10 PF00852.19 KFM72341.1 - 9.1e-26 90.6 0.0 1.3e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term AIP3 PF03915.13 KFM72342.1 - 1.5e-08 34.1 13.5 1.5e-08 34.1 13.5 2.3 2 1 0 2 2 2 1 Actin interacting protein 3 MmgE_PrpD PF03972.14 KFM72342.1 - 0.043 12.3 0.1 0.074 11.6 0.1 1.3 1 0 0 1 1 1 0 MmgE/PrpD family DUF4760 PF15956.5 KFM72343.1 - 0.031 14.4 0.1 0.049 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) DDE_Tnp_4 PF13359.6 KFM72344.1 - 3.9e-11 42.9 0.0 4.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM72344.1 - 1.3e-05 25.0 0.0 1.6e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Na_H_Exchanger PF00999.21 KFM72345.1 - 3.1e-11 42.7 0.1 3.2e-11 42.7 0.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Inhibitor_I78 PF11720.8 KFM72345.1 - 0.13 12.3 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Na_H_Exchanger PF00999.21 KFM72346.1 - 4.6e-17 61.9 2.9 4.9e-17 61.8 2.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 KFM72347.1 - 4.5e-05 22.4 2.5 6.4e-05 21.9 2.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Bul1_N PF04425.12 KFM72347.1 - 0.14 10.8 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Bul1 N terminus rve PF00665.26 KFM72348.1 - 1.2e-13 51.2 0.0 2.1e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM72348.1 - 1.6e-08 34.5 0.0 3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM72349.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72349.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SCAN PF02023.17 KFM72351.1 - 6.8e-05 22.6 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 SCAN domain PPDK_N PF01326.19 KFM72354.1 - 0.00041 19.7 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Exostosin PF03016.15 KFM72355.1 - 0.019 14.2 0.0 0.05 12.8 0.0 1.5 1 1 0 1 1 1 0 Exostosin family Herpes_glycoH_C PF17488.2 KFM72355.1 - 0.045 13.6 0.3 7.8 6.3 0.0 3.1 3 0 0 3 3 3 0 Herpesvirus glycoprotein H C-terminal domain DDE_Tnp_IS1595 PF12762.7 KFM72356.1 - 1.5e-20 73.7 0.0 3.5e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 ISXO2-like transposase domain MOZART2 PF12926.7 KFM72356.1 - 5.7e-18 64.3 0.0 1.1e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DDE_Tnp_1_7 PF13843.6 KFM72356.1 - 0.0028 17.0 0.1 0.0059 16.0 0.1 1.5 1 0 0 1 1 1 1 Transposase IS4 Img2 PF05046.14 KFM72357.1 - 6.3e-14 52.0 0.1 1.1e-13 51.2 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Sulfolobus_pRN PF05584.11 KFM72357.1 - 0.13 12.3 0.2 0.31 11.1 0.1 1.6 1 1 1 2 2 2 0 Sulfolobus plasmid regulatory protein Spermine_synth PF01564.17 KFM72358.1 - 3.5e-62 209.2 0.0 5.2e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KFM72358.1 - 2.7e-21 75.2 0.1 4.5e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KFM72358.1 - 0.00014 22.5 0.0 0.00036 21.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM72358.1 - 0.018 15.8 0.0 0.097 13.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFM72358.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_L22e PF01776.17 KFM72359.1 - 1.4e-48 163.8 3.2 1.8e-48 163.4 3.2 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family RPT PF13446.6 KFM72359.1 - 0.1 12.6 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein Pkinase PF00069.25 KFM72363.1 - 1.2e-60 205.2 0.0 1.5e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM72363.1 - 1.2e-24 87.1 0.0 1.9e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM72363.1 - 0.0098 15.3 0.1 0.026 13.9 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM72363.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFM72363.1 - 0.017 14.1 0.2 0.67 8.9 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PGAP1 PF07819.13 KFM72364.1 - 7.1e-08 32.4 0.1 9.9e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Tox-GHH PF15636.6 KFM72364.1 - 0.032 14.2 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Thioredoxin PF00085.20 KFM72367.1 - 7.2e-58 193.0 2.5 1.2e-05 25.2 0.0 14.2 15 0 0 15 15 15 11 Thioredoxin Thioredoxin_2 PF13098.6 KFM72367.1 - 3.8e-39 133.5 37.6 6.9e-05 23.3 0.0 20.2 16 7 0 16 16 16 10 Thioredoxin-like domain HyaE PF07449.11 KFM72367.1 - 2.5e-26 91.8 11.8 0.018 15.0 0.0 12.8 13 0 0 13 13 13 6 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KFM72367.1 - 6.3e-25 87.0 0.0 0.37 10.9 0.0 12.6 13 0 0 13 13 13 5 Thioredoxin domain AhpC-TSA PF00578.21 KFM72367.1 - 1.4e-23 83.2 15.5 0.041 13.8 0.0 12.1 12 0 0 12 12 12 7 AhpC/TSA family TraF PF13728.6 KFM72367.1 - 2.1e-20 73.5 5.0 0.017 14.9 0.0 12.4 12 2 0 12 12 12 4 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KFM72367.1 - 4.4e-20 71.8 18.4 0.85 10.0 0.0 15.5 16 1 1 17 17 16 4 Thioredoxin-like DUF836 PF05768.14 KFM72367.1 - 2.7e-14 53.3 10.2 0.052 14.0 0.0 8.8 8 0 0 8 8 8 4 Glutaredoxin-like domain (DUF836) W2 PF02020.18 KFM72367.1 - 3.7e-10 39.8 41.0 0.5 10.5 0.6 13.4 15 1 0 15 15 13 3 eIF4-gamma/eIF5/eIF2-epsilon Redoxin PF08534.10 KFM72367.1 - 6.8e-10 38.8 1.0 0.037 13.7 0.0 7.0 9 0 0 9 9 9 2 Redoxin Thioredoxin_5 PF13743.6 KFM72367.1 - 2.3e-08 33.9 11.8 3.5 7.3 0.0 10.4 13 1 1 14 14 14 1 Thioredoxin DUF393 PF04134.12 KFM72367.1 - 2.7e-08 35.1 10.9 0.077 14.3 0.0 7.8 9 0 0 9 9 8 2 Protein of unknown function, DUF393 Glutaredoxin PF00462.24 KFM72367.1 - 0.0063 16.7 2.0 43 4.4 0.0 5.7 5 0 0 5 5 5 0 Glutaredoxin DiS_P_DiS PF06750.13 KFM72367.1 - 0.0088 16.1 5.5 1.9 8.7 0.1 6.0 9 0 0 9 9 8 1 Bacterial Peptidase A24 N-terminal domain FYVE PF01363.21 KFM72367.1 - 0.037 14.2 1.6 0.3 11.3 0.5 3.0 2 0 0 2 2 2 0 FYVE zinc finger zf-HC3 PF16827.5 KFM72367.1 - 0.076 13.2 2.7 70 3.7 0.0 4.9 6 0 0 6 6 5 0 zinc-finger Peripla_BP_7 PF18610.1 KFM72367.1 - 0.092 12.9 0.1 6 7.1 0.0 4.0 3 0 0 3 3 3 0 Periplasmic binding protein domain Lipase_GDSL_3 PF14606.6 KFM72367.1 - 0.11 12.6 0.2 4.4 7.4 0.0 3.0 2 1 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family DUF2284 PF10050.9 KFM72367.1 - 0.34 10.6 2.4 33 4.2 0.0 4.3 7 0 0 7 7 6 0 Predicted metal-binding protein (DUF2284) zf-H2C2_2 PF13465.6 KFM72368.1 - 9.5e-28 95.4 19.0 6.4e-11 42.2 0.6 4.1 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72368.1 - 5.1e-19 67.6 24.4 2.8e-06 27.5 4.0 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72368.1 - 2.8e-15 55.7 21.2 9.6e-05 22.9 2.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf_UBZ PF18439.1 KFM72368.1 - 3.5e-06 26.5 7.6 0.31 10.7 0.1 3.3 3 0 0 3 3 3 3 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 KFM72368.1 - 2.3e-05 24.3 4.5 0.037 14.0 1.9 2.5 2 0 0 2 2 2 2 Adenylate kinase, active site lid Baculo_IE-1 PF05290.11 KFM72368.1 - 3.5e-05 23.8 2.6 0.64 10.0 0.0 3.0 1 1 2 3 3 3 2 Baculovirus immediate-early protein (IE-0) zf-met PF12874.7 KFM72368.1 - 5.8e-05 23.3 18.9 0.067 13.6 2.0 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM72368.1 - 0.00033 20.6 23.3 0.2 11.7 3.2 4.2 3 2 0 3 3 3 2 C2H2-type zinc finger zf-MYST PF17772.1 KFM72368.1 - 0.00047 19.7 12.8 0.37 10.4 0.1 3.1 1 1 2 3 3 3 3 MYST family zinc finger domain XPA_N PF01286.18 KFM72368.1 - 0.00084 19.3 5.2 3.3 7.8 0.3 3.2 3 0 0 3 3 3 1 XPA protein N-terminal Prok-RING_2 PF14445.6 KFM72368.1 - 0.0015 18.7 1.4 6.8 6.9 0.0 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 zf-AN1 PF01428.16 KFM72368.1 - 0.0034 17.5 13.8 0.22 11.7 3.0 3.1 2 1 1 3 3 3 2 AN1-like Zinc finger zf-C2H2_jaz PF12171.8 KFM72368.1 - 0.0038 17.5 16.5 0.59 10.5 1.1 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DZR PF12773.7 KFM72368.1 - 0.0074 16.3 5.5 0.24 11.5 5.5 2.1 1 1 0 1 1 1 1 Double zinc ribbon zf-CCHC_2 PF13696.6 KFM72368.1 - 0.01 15.7 11.8 0.15 11.9 0.5 3.2 3 0 0 3 3 3 2 Zinc knuckle zinc_ribbon_15 PF17032.5 KFM72368.1 - 0.011 16.5 6.6 0.14 12.9 6.6 2.0 1 1 0 1 1 1 0 zinc-ribbon family zf-C2HC_2 PF13913.6 KFM72368.1 - 0.014 15.3 9.1 1.8 8.5 0.1 3.5 3 1 0 3 3 3 0 zinc-finger of a C2HC-type GAGA PF09237.11 KFM72368.1 - 0.016 15.0 1.8 4 7.3 0.2 2.6 1 1 2 3 3 3 0 GAGA factor Zf_RING PF16744.5 KFM72368.1 - 0.027 14.6 6.8 2.4 8.3 0.4 3.0 1 1 2 3 3 3 0 KIAA1045 RING finger C1_1 PF00130.22 KFM72368.1 - 0.029 14.3 9.7 1.1 9.2 0.7 3.1 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 KFM72368.1 - 0.03 14.3 7.1 5.1 7.2 7.1 2.6 1 1 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KFM72368.1 - 0.034 14.3 6.1 0.74 10.0 1.8 2.7 1 1 2 3 3 3 0 Zinc ribbon domain zf_ZIC PF18366.1 KFM72368.1 - 0.039 14.1 10.9 2.8 8.1 1.1 3.2 1 1 2 3 3 3 0 Zic proteins zinc finger domain DUF2757 PF10955.8 KFM72368.1 - 0.057 13.7 6.2 5.8 7.3 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2757) C5HCH PF17982.1 KFM72368.1 - 0.059 13.5 9.6 1.6 8.9 0.5 3.1 2 1 1 3 3 3 0 NSD Cys-His rich domain zf-Sec23_Sec24 PF04810.15 KFM72368.1 - 0.066 13.3 5.7 6 7.0 0.1 3.0 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Laminin_EGF PF00053.24 KFM72368.1 - 0.076 13.2 5.1 6.7 6.9 0.4 3.1 2 1 1 3 3 3 0 Laminin EGF domain zf-RRPl_C4 PF17026.5 KFM72368.1 - 0.13 12.3 5.7 0.23 11.6 5.7 1.5 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type FYVE_2 PF02318.16 KFM72368.1 - 0.15 12.3 6.2 4.6 7.5 6.4 2.1 1 1 0 1 1 1 0 FYVE-type zinc finger Rep_fac-A_C PF08646.10 KFM72368.1 - 0.18 11.5 7.2 7.3 6.3 0.1 2.8 1 1 2 3 3 3 0 Replication factor-A C terminal domain Ta0938 PF11494.8 KFM72368.1 - 0.19 12.0 3.4 9.3 6.6 0.5 2.7 1 1 1 2 2 2 0 Ta0938 HNH_5 PF14279.6 KFM72368.1 - 0.21 11.5 10.8 13 5.8 0.1 3.0 1 1 2 3 3 3 0 HNH endonuclease CpXC PF14353.6 KFM72368.1 - 0.22 11.6 7.5 1.4 9.0 0.2 2.9 1 1 2 3 3 3 0 CpXC protein zf-C2H2_2 PF12756.7 KFM72368.1 - 0.24 11.8 17.5 4.2 7.8 4.3 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-nanos PF05741.13 KFM72368.1 - 0.25 11.6 8.9 29 5.0 6.3 3.1 2 1 0 2 2 2 0 Nanos RNA binding domain PHD PF00628.29 KFM72368.1 - 0.3 11.0 9.9 8.1 6.4 9.9 2.5 1 1 0 1 1 1 0 PHD-finger DUF4428 PF14471.6 KFM72368.1 - 0.32 11.0 8.4 1.2 9.1 3.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) Rpr2 PF04032.16 KFM72368.1 - 0.34 11.2 6.8 3 8.2 2.3 2.5 1 1 2 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2197 PF09963.9 KFM72368.1 - 0.41 10.9 9.7 6.9 7.0 5.1 3.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) LIM PF00412.22 KFM72368.1 - 0.59 10.4 10.0 14 6.0 5.9 2.7 1 1 0 2 2 2 0 LIM domain zf-trcl PF13451.6 KFM72368.1 - 0.73 9.8 5.9 16 5.5 0.2 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-C2H2_9 PF16293.5 KFM72368.1 - 1.3 9.0 9.6 2.8 7.9 0.4 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-AD PF07776.15 KFM72368.1 - 1.3 9.3 9.0 0.89 9.8 0.3 2.9 1 1 2 3 3 3 0 Zinc-finger associated domain (zf-AD) C1_4 PF07975.12 KFM72368.1 - 1.7 8.9 12.0 2.2 8.6 3.0 2.5 1 1 2 3 3 3 0 TFIIH C1-like domain FYVE PF01363.21 KFM72368.1 - 2.7 8.2 12.9 12 6.1 10.3 2.8 1 1 1 2 2 2 0 FYVE zinc finger TRAF6_Z2 PF18048.1 KFM72368.1 - 6.2 7.0 12.6 6.9 6.9 3.3 3.1 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf_C2H2_ZHX PF18387.1 KFM72368.1 - 7.6 6.3 15.2 1.4 8.6 1.8 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain AAA_33 PF13671.6 KFM72369.1 - 3.7e-07 30.4 0.0 4.8e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM72369.1 - 0.011 16.3 0.0 0.016 15.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFM72369.1 - 0.048 13.4 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFM72369.1 - 0.049 13.6 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KFM72369.1 - 0.076 13.4 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFM72369.1 - 0.092 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 KFM72369.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 KFM72369.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.7 1 1 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 KFM72369.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 NACHT domain Hydin_ADK PF17213.3 KFM72369.1 - 0.14 12.5 0.0 0.23 11.7 0.0 1.3 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain Ploopntkinase3 PF18751.1 KFM72369.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.7 1 1 0 2 2 2 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KFM72369.1 - 0.15 12.6 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 KFM72369.1 - 0.18 11.2 0.3 0.35 10.2 0.1 1.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFM72370.1 - 1.1e-08 35.3 0.0 3.6e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFM72370.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM72370.1 - 0.057 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KFM72370.1 - 0.078 12.2 0.3 3.1 7.0 0.3 3.0 2 1 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KFM72370.1 - 0.13 12.8 0.0 0.5 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 KFM72370.1 - 0.14 12.4 0.0 0.45 10.8 0.0 1.8 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA PF00004.29 KFM72370.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nup84_Nup100 PF04121.13 KFM72371.1 - 2.4e-182 607.9 16.9 2.7e-182 607.7 16.9 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF2063 PF09836.9 KFM72371.1 - 0.12 12.6 0.2 8.3 6.7 0.2 2.7 2 0 0 2 2 2 0 Putative DNA-binding domain Dimer_Tnp_hAT PF05699.14 KFM72372.1 - 1.6e-06 27.8 0.3 9.3e-06 25.3 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KFM72372.1 - 0.06 13.7 0.9 0.11 12.9 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Cadherin_3 PF16184.5 KFM72374.1 - 1.3e-34 118.6 0.2 1.2e-22 80.0 0.0 2.3 2 0 0 2 2 2 2 Cadherin-like Laminin_G_2 PF02210.24 KFM72374.1 - 1.1e-12 48.6 0.3 4.6e-12 46.6 0.2 2.1 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.23 KFM72374.1 - 6.5e-10 39.3 0.0 1.6e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 Laminin G domain Big_9 PF17963.1 KFM72374.1 - 0.0036 18.0 0.1 0.041 14.6 0.1 2.5 2 1 0 2 2 2 1 Bacterial Ig domain Laminin_G_3 PF13385.6 KFM72374.1 - 0.017 15.3 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 KFM72374.1 - 0.12 13.1 1.5 0.32 11.7 1.5 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_3 PF12947.7 KFM72374.1 - 2 8.7 5.2 3.9 7.8 5.2 1.5 1 0 0 1 1 1 0 EGF domain Cadherin_3 PF16184.5 KFM72375.1 - 8.3e-145 473.3 32.1 1.7e-31 108.5 0.1 10.3 10 0 0 10 10 10 10 Cadherin-like Cadherin_4 PF17803.1 KFM72375.1 - 2.6e-05 24.7 20.9 0.33 11.6 3.1 5.7 5 0 0 5 5 5 4 Bacterial cadherin-like domain LRR19-TM PF15176.6 KFM72375.1 - 0.0076 16.2 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain EphA2_TM PF14575.6 KFM72375.1 - 0.11 13.4 0.0 0.3 12.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KFM72375.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator OAD_gamma PF04277.13 KFM72376.1 - 0.2 12.3 4.0 0.23 12.1 4.0 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SR-25 PF10500.9 KFM72376.1 - 1.2 8.7 17.2 1.1 8.8 17.2 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 KFM72376.1 - 3.1 8.0 13.5 2.9 8.1 13.5 1.0 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 LapA_dom PF06305.11 KFM72376.1 - 9.7 6.1 7.7 13 5.7 7.7 1.3 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PAS_11 PF14598.6 KFM72377.1 - 6.3e-18 65.0 0.2 5.8e-14 52.2 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 KFM72377.1 - 3.3e-14 52.9 0.1 2e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFM72377.1 - 2e-10 40.4 2.0 2.5e-10 40.1 0.5 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 KFM72377.1 - 8.1e-08 32.3 0.0 0.00044 20.2 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFM72377.1 - 0.00021 21.5 0.0 0.095 13.0 0.0 2.9 2 0 0 2 2 2 2 PAS domain HTH_Tnp_Tc3_2 PF01498.18 KFM72378.1 - 2.2e-17 63.0 2.7 4.9e-17 61.9 2.7 1.6 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KFM72378.1 - 2.3e-05 24.4 0.1 2.3e-05 24.4 0.1 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72378.1 - 0.00065 19.4 1.0 0.019 14.7 0.1 2.6 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM72378.1 - 0.0063 16.1 0.0 0.029 14.0 0.0 2.1 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 KFM72378.1 - 0.0076 16.8 1.7 0.0076 16.8 1.7 2.7 3 0 0 3 3 3 1 Homeodomain-like domain DDE_3 PF13358.6 KFM72378.1 - 0.015 15.1 0.3 1 9.1 0.1 2.4 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.6 KFM72378.1 - 0.04 13.3 2.8 0.061 12.7 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 KFM72378.1 - 0.063 13.2 0.4 3.6 7.6 0.0 2.7 1 1 1 2 2 2 0 MarR family RVT_1 PF00078.27 KFM72378.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PAX PF00292.18 KFM72378.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain Cu2_monoox_C PF03712.15 KFM72379.1 - 3.8e-40 137.0 0.0 7.1e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KFM72379.1 - 1.1e-38 132.4 0.9 1.9e-38 131.7 0.9 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 KFM72379.1 - 5.5e-32 110.6 0.0 1.2e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 DOMON domain CDH-cyt PF16010.5 KFM72379.1 - 0.0019 17.9 0.0 0.0066 16.1 0.0 1.9 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase Hormone_recep PF00104.30 KFM72382.1 - 3.9e-46 157.2 0.1 5.5e-46 156.8 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ig_3 PF13927.6 KFM72383.1 - 1.7e-10 41.3 0.0 4.2e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM72383.1 - 1.6e-07 31.4 0.0 3.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM72383.1 - 5.7e-07 29.5 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFM72383.1 - 1e-06 28.9 0.0 5.7e-05 23.2 0.0 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM72383.1 - 2.7e-05 24.4 0.0 6.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain TSP_1 PF00090.19 KFM72383.1 - 0.00019 21.6 0.7 0.00042 20.5 0.7 1.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain Ig_6 PF18452.1 KFM72383.1 - 0.0087 15.6 0.0 0.027 14.0 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain PLAC PF08686.11 KFM72384.1 - 2.9e-07 31.1 9.1 7.7e-07 29.8 9.1 1.7 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain BORCS8 PF10167.9 KFM72385.1 - 8.6e-44 148.1 6.7 1e-43 147.8 6.7 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 Fzo_mitofusin PF04799.13 KFM72385.1 - 0.052 13.1 1.0 0.11 12.0 1.0 1.6 1 1 1 2 2 2 0 fzo-like conserved region zf-RING_2 PF13639.6 KFM72386.1 - 6e-13 48.9 17.5 1.6e-12 47.5 8.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM72386.1 - 2.8e-09 36.6 8.4 2.8e-09 36.6 8.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KFM72386.1 - 1.3e-08 34.9 2.0 1.3e-08 34.9 2.0 2.6 2 0 0 2 2 2 1 zinc-ribbon zf-RING_11 PF17123.5 KFM72386.1 - 1.6e-08 34.2 4.7 1.6e-08 34.2 4.7 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KFM72386.1 - 7.3e-07 29.4 6.2 7.3e-07 29.4 6.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM72386.1 - 4.8e-06 26.5 2.3 4.8e-06 26.5 2.3 3.2 2 2 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM72386.1 - 5e-06 26.4 16.6 1.5e-05 24.9 6.5 2.3 2 0 0 2 2 2 2 zinc-RING finger domain HypA PF01155.19 KFM72386.1 - 3.5e-05 23.8 4.8 0.0019 18.2 0.2 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4 PF00097.25 KFM72386.1 - 5.9e-05 22.9 7.3 5.9e-05 22.9 7.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM72386.1 - 0.00018 21.3 11.7 0.0059 16.4 5.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM72386.1 - 0.00055 19.8 11.9 0.061 13.2 5.8 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFM72386.1 - 0.0021 18.1 4.3 0.0021 18.1 4.3 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KFM72386.1 - 0.0033 17.4 7.2 0.011 15.8 0.5 2.4 2 1 0 2 2 2 1 Double zinc ribbon zf-Nse PF11789.8 KFM72386.1 - 0.0084 15.9 4.0 0.018 14.8 4.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf_UBZ PF18439.1 KFM72386.1 - 0.027 14.1 5.9 4 7.1 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C4_Topoisom PF01396.19 KFM72386.1 - 0.073 12.9 0.3 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-C3HC4_4 PF15227.6 KFM72386.1 - 0.13 12.4 12.9 1.4 9.2 5.1 3.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 KFM72386.1 - 0.34 10.9 9.7 0.35 10.9 0.3 2.9 2 1 0 2 2 2 0 zinc-ribbons zf-RING_6 PF14835.6 KFM72386.1 - 0.46 10.4 5.5 0.07 13.0 1.0 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFM72386.1 - 0.48 10.6 7.8 0.19 11.9 3.3 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 Zn_ribbon_SprT PF17283.2 KFM72386.1 - 2.3 8.2 9.1 14 5.7 0.1 3.7 3 1 0 3 3 3 0 SprT-like zinc ribbon domain zf-HC5HC2H PF13771.6 KFM72386.1 - 4.2 7.7 7.6 0.64 10.3 2.8 2.1 2 1 0 2 2 2 0 PHD-like zinc-binding domain zf-HIT PF04438.16 KFM72386.1 - 4.6 7.2 10.3 2.4 8.1 1.4 3.0 3 0 0 3 3 3 0 HIT zinc finger zf-RING_4 PF14570.6 KFM72386.1 - 5.2 6.9 14.1 3 7.7 5.0 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KFM72386.1 - 5.7 6.9 17.4 30 4.6 7.0 3.8 2 2 2 4 4 4 0 PHD-finger DDE_3 PF13358.6 KFM72387.1 - 1.6e-05 24.7 0.0 2.9e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease fn3 PF00041.21 KFM72389.1 - 1.5e-07 31.7 0.0 3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain TMEM156 PF15106.6 KFM72389.1 - 0.0018 17.7 0.5 0.0027 17.2 0.5 1.2 1 0 0 1 1 1 1 TMEM156 protein family Shisa PF13908.6 KFM72389.1 - 0.0041 17.4 0.1 0.0067 16.7 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 KFM72389.1 - 0.0046 16.9 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 KFM72389.1 - 0.0065 17.3 0.0 0.012 16.5 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 KFM72389.1 - 0.028 14.9 0.3 0.051 14.0 0.3 1.5 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Cadherin_C_2 PF16492.5 KFM72389.1 - 0.043 14.6 0.2 0.12 13.2 0.2 1.7 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Pns11_12 PF17464.2 KFM72389.1 - 0.049 13.3 1.7 0.078 12.7 1.7 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 CD34_antigen PF06365.12 KFM72389.1 - 0.056 13.0 0.1 0.077 12.6 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DAG1 PF05454.11 KFM72389.1 - 0.097 12.0 0.1 0.19 11.1 0.0 1.4 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) fn3 PF00041.21 KFM72390.1 - 7.1e-09 35.9 0.1 9.2e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Ig_3 PF13927.6 KFM72392.1 - 3.2e-56 187.9 0.2 1.4e-13 51.2 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 KFM72392.1 - 2.9e-55 184.3 0.0 1.9e-14 53.5 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM72392.1 - 6.2e-38 129.0 0.1 4.8e-09 36.4 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFM72392.1 - 3.6e-32 110.4 0.0 3.3e-08 33.6 0.0 4.4 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFM72392.1 - 5.7e-23 81.2 8.3 0.0007 19.7 0.1 7.5 5 3 1 6 6 6 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM72392.1 - 4.2e-12 46.3 0.0 0.0072 16.7 0.0 5.0 4 1 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM72392.1 - 6.2e-11 41.7 0.0 0.093 12.3 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain Izumo-Ig PF16706.5 KFM72392.1 - 4.4e-08 33.1 0.0 0.71 10.0 0.0 4.5 4 0 0 4 4 4 3 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFM72392.1 - 4.6e-07 29.8 0.1 0.11 12.6 0.0 4.3 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM72392.1 - 1.5e-06 28.3 0.0 0.068 13.4 0.0 4.5 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFM72392.1 - 0.0007 19.9 0.2 3.8 7.9 0.0 3.9 3 1 0 3 3 3 2 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 KFM72392.1 - 0.0039 17.4 0.0 3.5 7.9 0.0 3.4 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Pox_C7_F8A PF03287.14 KFM72392.1 - 0.0076 16.2 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 Poxvirus C7/F8A protein DUF3954 PF13128.6 KFM72392.1 - 0.012 15.4 0.1 6.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3954) tRNA_Me_trans PF03054.16 KFM72394.1 - 0.082 11.7 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase TFIIF_beta_N PF17683.1 KFM72396.1 - 5.9e-14 52.9 0.0 8.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus eIF-6 PF01912.18 KFM72397.1 - 2.8e-81 271.6 0.6 4.4e-81 271.0 0.6 1.3 1 0 0 1 1 1 1 eIF-6 family Glyco_transf_22 PF03901.17 KFM72398.1 - 1.5e-25 90.3 22.8 1.2e-15 57.7 12.3 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family WASH_WAHD PF11945.8 KFM72399.1 - 3.7e-91 305.7 1.9 5.9e-91 305.0 1.9 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.20 KFM72399.1 - 0.059 13.2 4.9 0.22 11.4 2.4 2.7 2 1 0 2 2 2 0 WH2 motif RVT_1 PF00078.27 KFM72400.1 - 4e-10 39.6 0.0 1.6e-09 37.6 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 KFM72400.1 - 0.00055 20.4 0.0 0.0016 19.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KFM72400.1 - 0.006 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 KFM72400.1 - 0.03 14.4 3.2 0.03 14.4 3.2 2.6 2 0 0 2 2 2 0 Zinc knuckle Asp_protease_2 PF13650.6 KFM72400.1 - 0.036 14.7 0.0 0.085 13.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 KFM72400.1 - 0.069 13.5 0.0 0.58 10.5 0.0 2.6 3 0 0 3 3 3 0 Retroviral aspartyl protease G-patch PF01585.23 KFM72401.1 - 1.3e-14 53.7 4.9 3e-14 52.6 4.9 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFM72401.1 - 8.9e-05 22.5 2.6 8.9e-05 22.5 2.6 2.6 3 0 0 3 3 3 1 G-patch domain DM13 PF10517.9 KFM72402.1 - 2e-06 28.3 0.1 2.6e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Electron transfer DM13 DOMON PF03351.17 KFM72403.1 - 5e-22 78.4 0.1 2.4e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 DOMON domain DM13 PF10517.9 KFM72403.1 - 6.2e-21 74.9 0.5 4.1e-20 72.3 0.0 2.8 3 0 0 3 3 3 1 Electron transfer DM13 SSP160 PF06933.11 KFM72403.1 - 0.18 9.9 2.4 0.32 9.1 2.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DDE_Tnp_IS1595 PF12762.7 KFM72405.1 - 4.3e-14 52.8 0.0 6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain zf-H2C2_2 PF13465.6 KFM72406.1 - 8.6e-100 323.1 101.6 1.2e-08 35.0 0.6 14.8 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72406.1 - 2.4e-58 191.5 116.1 1.1e-05 25.6 0.7 14.1 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72406.1 - 5.4e-48 157.5 104.4 0.001 19.7 1.3 14.1 14 0 0 14 14 14 13 C2H2-type zinc finger zf-met PF12874.7 KFM72406.1 - 6.2e-39 131.3 97.5 0.0025 18.2 1.7 14.2 14 0 0 14 14 14 14 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM72406.1 - 1.6e-27 95.1 67.0 0.061 13.6 0.6 14.2 14 0 0 14 14 14 13 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM72406.1 - 1.2e-19 69.7 72.3 0.0073 16.0 0.5 13.9 14 0 0 14 14 14 10 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM72406.1 - 1.7e-19 69.3 84.4 0.027 14.5 0.6 14.6 14 0 0 14 14 14 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM72406.1 - 1.1e-13 50.6 67.1 0.17 11.7 0.1 13.5 13 0 0 13 13 13 7 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM72406.1 - 5e-09 36.1 48.8 0.0076 16.3 1.1 12.6 9 2 4 13 13 13 3 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM72406.1 - 1.4e-07 31.2 64.5 0.17 11.8 0.4 13.8 14 0 0 14 14 14 3 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM72406.1 - 1.7e-06 28.1 52.1 0.22 11.6 5.2 5.9 1 1 4 5 5 5 4 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM72406.1 - 8e-06 25.9 54.7 3.1 8.0 0.2 12.4 13 0 0 13 13 13 2 DBF zinc finger Tox-HNH-HHH PF15637.6 KFM72406.1 - 0.00019 21.6 6.7 0.5 10.6 0.0 5.4 1 1 5 7 7 7 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF2256 PF10013.9 KFM72406.1 - 0.00028 20.9 53.3 13 6.0 0.1 13.0 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 KFM72406.1 - 0.00048 19.9 31.5 0.86 9.5 0.9 9.2 1 1 10 12 12 12 3 GAGA factor zinc_ribbon_15 PF17032.5 KFM72406.1 - 0.0055 17.4 54.6 0.5 11.2 2.5 7.2 1 1 10 11 11 11 3 zinc-ribbon family C1_1 PF00130.22 KFM72406.1 - 0.017 15.0 72.6 4.2 7.3 3.3 11.7 1 1 12 13 13 13 0 Phorbol esters/diacylglycerol binding domain (C1 domain) BolA PF01722.18 KFM72406.1 - 0.021 15.1 19.7 6.9 7.0 0.0 7.8 1 1 6 7 7 7 0 BolA-like protein ADK_lid PF05191.14 KFM72406.1 - 0.053 13.5 0.8 0.053 13.5 0.8 8.1 5 3 2 7 7 7 0 Adenylate kinase, active site lid NusB PF01029.18 KFM72406.1 - 0.17 12.1 0.2 16 5.7 0.0 3.3 2 2 2 4 4 4 0 NusB family zf-C2H2_9 PF16293.5 KFM72406.1 - 0.63 9.9 52.5 6.7 6.6 0.1 12.6 4 4 10 14 14 14 0 C2H2 type zinc-finger (1 copy) zf-RING_UBOX PF13445.6 KFM72406.1 - 1.8 8.7 22.9 1.5e+02 2.5 0.1 9.9 12 0 0 12 12 12 0 RING-type zinc-finger zf-Paramyx-P PF13008.7 KFM72406.1 - 2.7 7.5 45.4 0.25 10.8 0.6 11.3 12 0 0 12 12 12 0 Zinc-binding domain of Paramyxoviridae V protein HTH_Tnp_Tc3_2 PF01498.18 KFM72407.1 - 2.2e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72407.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM72408.1 - 3.2e-11 43.2 0.0 4.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72409.1 - 4.8e-16 58.8 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72409.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72409.1 - 2e-07 30.7 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72409.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain RVT_1 PF00078.27 KFM72410.1 - 1.3e-28 100.0 0.2 2.6e-28 99.0 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 KFM72410.1 - 9.7e-10 38.9 0.0 3.7e-09 37.0 0.0 2.0 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM72410.1 - 5.8e-06 26.9 0.0 1.5e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM72410.1 - 9.2e-06 25.9 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KFM72410.1 - 4.4e-05 23.3 0.0 8.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KFM72410.1 - 0.0016 18.2 0.1 0.0029 17.4 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Arc_C PF18162.1 KFM72410.1 - 0.011 15.6 2.7 0.022 14.6 0.5 2.4 2 0 0 2 2 2 0 Arc C-lobe BH4 PF02180.17 KFM72410.1 - 0.025 14.4 0.1 0.063 13.1 0.1 1.7 1 0 0 1 1 1 0 Bcl-2 homology region 4 VirB3 PF05101.13 KFM72411.1 - 0.023 14.9 0.8 0.032 14.5 0.8 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM72412.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72412.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72412.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72412.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72412.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF1758 PF05585.12 KFM72413.1 - 2.4e-11 43.7 1.8 2.8e-11 43.4 0.1 2.0 2 0 0 2 2 1 1 Putative peptidase (DUF1758) Apolipoprotein PF01442.18 KFM72413.1 - 2.7e-06 27.4 9.3 4.6e-06 26.6 9.3 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain gag-asp_proteas PF13975.6 KFM72413.1 - 0.00038 21.0 0.1 0.0016 18.9 0.0 2.1 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM72413.1 - 0.0006 20.4 0.0 0.0018 18.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DNA_primase_lrg PF04104.14 KFM72413.1 - 0.001 18.5 0.5 0.001 18.5 0.5 2.3 2 1 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit ApoLp-III PF07464.11 KFM72413.1 - 0.0015 18.7 14.3 0.022 14.8 16.1 2.0 2 0 0 2 2 1 1 Apolipophorin-III precursor (apoLp-III) YniB PF14002.6 KFM72413.1 - 0.0016 18.3 0.2 0.0054 16.5 0.2 1.9 1 0 0 1 1 1 1 YniB-like protein Baculo_PEP_C PF04513.12 KFM72413.1 - 0.0022 18.1 1.5 0.065 13.3 0.1 3.3 3 1 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 KFM72413.1 - 0.0038 17.2 4.0 0.0038 17.2 4.0 2.6 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) BLOC1_2 PF10046.9 KFM72413.1 - 0.0071 16.6 4.5 0.033 14.5 4.5 2.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KFM72413.1 - 0.0099 15.9 10.5 0.0099 15.9 10.5 1.9 2 0 0 2 2 1 1 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFM72413.1 - 0.028 14.8 6.8 0.028 14.8 6.8 3.4 3 2 0 3 3 2 0 Flagella accessory protein C (FlaC) Tweety PF04906.13 KFM72413.1 - 0.03 13.0 1.3 0.048 12.3 0.6 1.7 1 1 0 1 1 1 0 Tweety HSBP1 PF06825.12 KFM72413.1 - 0.031 14.1 0.5 0.11 12.3 0.3 2.1 1 1 1 2 2 2 0 Heat shock factor binding protein 1 Tropomyosin_1 PF12718.7 KFM72413.1 - 0.037 14.2 11.6 0.091 12.9 11.6 1.6 1 0 0 1 1 1 0 Tropomyosin like RVP PF00077.20 KFM72413.1 - 0.038 14.3 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 1 0 Retroviral aspartyl protease Exonuc_VII_L PF02601.15 KFM72413.1 - 0.039 13.5 1.1 0.07 12.7 1.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4795 PF16043.5 KFM72413.1 - 0.056 13.0 10.7 0.045 13.4 8.5 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4795) bZIP_1 PF00170.21 KFM72413.1 - 0.077 13.1 2.0 0.15 12.2 1.2 2.0 1 1 0 1 1 1 0 bZIP transcription factor Asp_protease PF09668.10 KFM72413.1 - 0.08 12.7 2.1 0.52 10.1 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease ApoO PF09769.9 KFM72413.1 - 0.09 12.7 3.2 1.4 8.9 0.5 3.3 2 1 1 3 3 2 0 Apolipoprotein O DUF1640 PF07798.11 KFM72413.1 - 0.18 11.9 12.3 0.055 13.5 9.2 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1640) Tup_N PF08581.10 KFM72413.1 - 0.2 12.0 6.4 0.76 10.1 6.4 2.1 1 0 0 1 1 1 0 Tup N-terminal Med9 PF07544.13 KFM72413.1 - 0.25 11.5 2.2 0.68 10.1 1.6 2.1 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.11 KFM72413.1 - 0.26 11.4 14.4 0.033 14.3 4.0 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SKA1 PF07160.12 KFM72413.1 - 0.26 11.1 5.9 0.3 10.9 4.2 2.0 2 0 0 2 2 1 0 Spindle and kinetochore-associated protein 1 DUF5082 PF16888.5 KFM72413.1 - 0.31 11.3 6.4 1.8 8.9 6.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) HrpB7 PF09486.10 KFM72413.1 - 0.35 11.2 5.6 0.58 10.5 5.6 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) SKA2 PF16740.5 KFM72413.1 - 0.36 10.6 7.0 0.6 9.9 5.4 2.3 2 1 0 2 2 1 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 KFM72413.1 - 0.47 9.3 12.2 0.76 8.6 12.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KFM72413.1 - 0.49 9.7 3.7 0.85 8.9 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 KFM72413.1 - 0.49 10.6 10.6 3.4 7.9 0.5 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF883 PF05957.13 KFM72413.1 - 0.59 10.8 7.6 2.3 8.9 0.7 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF148 PF02520.17 KFM72413.1 - 0.67 10.1 8.6 3.7 7.7 8.6 2.3 1 1 0 1 1 1 0 Domain of unknown function DUF148 Spectrin PF00435.21 KFM72413.1 - 0.7 10.4 5.4 2.3 8.8 4.8 2.3 2 1 0 2 2 1 0 Spectrin repeat Phage_Mu_Gam PF07352.12 KFM72413.1 - 0.7 9.8 10.0 1.1 9.1 0.7 2.6 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF4854 PF16146.5 KFM72413.1 - 0.72 10.2 9.9 5.6 7.4 6.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4854) CdvA PF18822.1 KFM72413.1 - 1 9.2 18.9 1.2 9.0 2.4 3.4 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Snapin_Pallidin PF14712.6 KFM72413.1 - 1.1 9.8 5.6 3 8.3 4.5 2.5 2 1 0 2 2 1 0 Snapin/Pallidin DUF948 PF06103.11 KFM72413.1 - 1.1 9.6 8.4 0.15 12.3 1.4 3.0 3 1 1 4 4 2 0 Bacterial protein of unknown function (DUF948) PIN_8 PF18476.1 KFM72413.1 - 1.3 8.8 7.4 3.6 7.4 7.4 1.7 1 0 0 1 1 1 0 PIN like domain ABC_tran_CTD PF16326.5 KFM72413.1 - 1.6 9.1 6.1 1 9.7 1.0 3.0 1 1 2 3 3 3 0 ABC transporter C-terminal domain MtrG PF04210.13 KFM72413.1 - 1.6 8.7 3.3 4.4 7.2 0.2 2.5 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G XhlA PF10779.9 KFM72413.1 - 1.9 8.7 5.8 1.5 9.1 2.9 2.4 1 1 1 2 2 2 0 Haemolysin XhlA DUF3584 PF12128.8 KFM72413.1 - 2.5 5.5 10.9 3.3 5.1 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YojJ PF10372.9 KFM72413.1 - 2.5 8.3 5.4 6.4 7.0 1.7 2.8 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus Fib_alpha PF08702.10 KFM72413.1 - 2.5 8.3 7.5 14 5.9 7.5 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 KFM72413.1 - 2.6 8.0 16.0 0.41 10.6 2.6 3.3 1 1 2 3 3 3 0 Prefoldin subunit Osmo_CC PF08946.10 KFM72413.1 - 2.8 8.3 6.5 8.5 6.7 1.6 3.0 1 1 2 3 3 3 0 Osmosensory transporter coiled coil DUF2884 PF11101.8 KFM72413.1 - 3.3 7.2 12.9 11 5.5 10.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2884) Fzo_mitofusin PF04799.13 KFM72413.1 - 3.5 7.2 10.0 7.7 6.0 3.5 2.5 1 1 1 2 2 2 0 fzo-like conserved region End3 PF12761.7 KFM72413.1 - 4.6 7.4 8.1 56 3.8 8.2 2.3 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 TPR_MLP1_2 PF07926.12 KFM72413.1 - 6.5 6.8 12.3 27 4.8 12.3 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 KFM72413.1 - 6.6 5.9 6.8 12 5.0 6.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein Laminin_II PF06009.12 KFM72413.1 - 6.9 6.7 15.2 0.61 10.1 8.6 2.5 3 0 0 3 3 2 0 Laminin Domain II Peptidase_M16 PF00675.20 KFM72414.1 - 6.5e-36 123.6 0.0 9.9e-35 119.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFM72414.1 - 2.2e-35 122.3 0.0 3.7e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF2695 PF10905.8 KFM72414.1 - 0.0049 17.1 0.1 0.012 15.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2695) DUF4788 PF16032.5 KFM72414.1 - 0.11 11.4 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) MeaB PF03308.16 KFM72415.1 - 8.2e-91 303.7 0.0 1.1e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KFM72415.1 - 4.2e-10 39.5 0.0 7.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KFM72415.1 - 3.1e-05 23.9 0.3 8.4e-05 22.5 0.1 1.8 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KFM72415.1 - 5.3e-05 23.0 0.2 0.0001 22.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFM72415.1 - 0.00011 22.1 0.2 0.00024 21.1 0.2 1.5 1 0 0 1 1 1 1 NTPase CbiA PF01656.23 KFM72415.1 - 0.00044 20.3 0.0 0.00081 19.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KFM72415.1 - 0.0011 19.5 1.2 0.0053 17.3 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFM72415.1 - 0.0012 19.1 0.3 0.0063 16.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFM72415.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFM72415.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Thymidylate kinase SRP54 PF00448.22 KFM72415.1 - 0.0027 17.4 0.0 0.042 13.5 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KFM72415.1 - 0.0031 17.6 0.1 0.036 14.2 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KFM72415.1 - 0.0035 17.1 0.1 0.0072 16.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CLP1_P PF16575.5 KFM72415.1 - 0.0048 16.7 0.1 0.013 15.3 0.0 1.7 1 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ABC_tran PF00005.27 KFM72415.1 - 0.007 16.9 0.3 0.018 15.6 0.2 1.7 1 1 0 1 1 1 1 ABC transporter KTI12 PF08433.10 KFM72415.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.14 KFM72415.1 - 0.015 15.2 0.1 0.038 13.9 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KFM72415.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM72415.1 - 0.025 14.5 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase PRK PF00485.18 KFM72415.1 - 0.025 14.3 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 KFM72415.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_31 PF13614.6 KFM72415.1 - 0.035 14.0 0.2 0.27 11.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KFM72415.1 - 0.048 13.0 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.14 KFM72415.1 - 0.05 12.8 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.17 KFM72415.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 KFM72415.1 - 0.06 13.7 0.2 0.21 11.9 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 KFM72415.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 KFM72415.1 - 0.071 13.4 0.7 0.34 11.2 0.3 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFM72415.1 - 0.075 13.0 0.4 0.15 12.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 KFM72415.1 - 0.089 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM72416.1 - 1.6e-17 63.5 1.4 3.4e-17 62.5 1.4 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72416.1 - 3.8e-10 39.7 0.0 6.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM72416.1 - 4.6e-06 27.2 2.3 4.6e-06 27.2 2.3 2.7 3 0 0 3 3 3 1 Homeodomain-like domain MarR_2 PF12802.7 KFM72416.1 - 0.001 18.9 0.2 0.084 12.8 0.0 2.5 2 0 0 2 2 2 1 MarR family HTH_28 PF13518.6 KFM72416.1 - 0.0023 18.0 1.0 0.069 13.3 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KFM72416.1 - 0.0044 17.0 0.5 0.17 11.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_23 PF13384.6 KFM72416.1 - 0.0052 16.6 0.6 0.21 11.4 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM72416.1 - 0.0076 16.2 0.8 0.059 13.3 0.0 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain PAX PF00292.18 KFM72416.1 - 0.0092 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_24 PF13412.6 KFM72416.1 - 0.039 13.5 0.8 1.1 8.9 0.0 2.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding rve PF00665.26 KFM72417.1 - 0.0015 18.7 0.0 0.0058 16.8 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain rve_3 PF13683.6 KFM72417.1 - 0.03 14.1 0.0 0.09 12.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain DUF1775 PF07987.11 KFM72417.1 - 0.041 14.1 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) DDE_Tnp_1_7 PF13843.6 KFM72419.1 - 2.4e-78 263.9 0.0 3.2e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Strep_SA_rep PF06696.11 KFM72419.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DDE_3 PF13358.6 KFM72421.1 - 2.6e-07 30.5 0.0 2.8e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease LRRFIP PF09738.9 KFM72422.1 - 1.1e-32 113.8 10.8 1.2e-32 113.6 10.8 1.0 1 0 0 1 1 1 1 LRRFIP family Syntaxin_2 PF14523.6 KFM72422.1 - 0.0022 18.3 3.0 0.0022 18.3 3.0 2.3 1 1 1 2 2 2 1 Syntaxin-like protein BRE1 PF08647.11 KFM72422.1 - 0.0073 16.4 6.1 0.012 15.7 6.1 1.4 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase HALZ PF02183.18 KFM72422.1 - 0.0079 16.4 4.0 0.0079 16.4 4.0 2.5 1 1 1 2 2 2 1 Homeobox associated leucine zipper GAS PF13851.6 KFM72422.1 - 0.016 14.6 10.6 0.021 14.2 10.6 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KFM72422.1 - 0.019 15.0 12.1 0.032 14.3 12.1 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2951 PF11166.8 KFM72422.1 - 0.021 15.0 3.6 0.029 14.6 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) She9_MDM33 PF05546.11 KFM72422.1 - 0.028 14.2 7.0 0.03 14.1 6.8 1.3 1 1 0 1 1 1 0 She9 / Mdm33 family DUF1664 PF07889.12 KFM72422.1 - 0.075 13.1 2.5 0.11 12.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PI_PP_I PF18363.1 KFM72422.1 - 0.098 12.8 1.1 0.14 12.4 1.1 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain DUF948 PF06103.11 KFM72422.1 - 0.12 12.6 1.7 0.41 10.9 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TSC22 PF01166.18 KFM72422.1 - 0.21 11.9 9.4 0.18 12.1 2.9 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family FAM76 PF16046.5 KFM72422.1 - 0.4 10.0 8.4 1.4 8.2 3.0 2.0 1 1 1 2 2 2 0 FAM76 protein FapA PF03961.13 KFM72422.1 - 0.44 9.1 7.5 0.46 9.0 7.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 KFM72422.1 - 0.45 10.9 13.5 0.11 12.8 10.3 1.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.22 KFM72422.1 - 0.57 10.4 8.6 0.086 13.1 2.4 2.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Csm1_N PF18504.1 KFM72422.1 - 0.74 10.2 11.9 3.3 8.1 3.7 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain YabA PF06156.13 KFM72422.1 - 0.95 10.1 7.0 1.4 9.6 7.0 1.5 1 1 0 1 1 1 0 Initiation control protein YabA bZIP_1 PF00170.21 KFM72422.1 - 0.97 9.6 15.2 2.4 8.3 1.4 3.0 3 0 0 3 3 3 0 bZIP transcription factor TMPIT PF07851.13 KFM72422.1 - 1 8.5 4.8 1 8.5 4.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 KFM72422.1 - 1.4 9.4 7.3 0.47 10.9 3.1 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 KFM72422.1 - 1.4 9.4 12.7 0.83 10.1 10.2 2.0 2 1 0 2 2 1 0 Cell division protein ZapB V_ATPase_I PF01496.19 KFM72422.1 - 1.5 6.6 6.1 1.6 6.6 6.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 KFM72422.1 - 2.4 8.3 14.8 0.1 12.7 3.5 3.1 2 1 1 3 3 3 0 Basic region leucine zipper LMBR1 PF04791.16 KFM72422.1 - 4.9 6.0 4.7 5.2 5.9 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LRRFIP PF09738.9 KFM72423.1 - 7.1e-18 65.1 5.7 7.8e-18 65.0 5.7 1.0 1 0 0 1 1 1 1 LRRFIP family G-gamma PF00631.22 KFM72423.1 - 0.5 10.4 4.4 0.19 11.8 1.9 1.5 2 0 0 2 2 2 0 GGL domain DUF5600 PF18150.1 KFM72424.1 - 2.1e-45 153.7 1.7 3.6e-45 153.0 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KFM72424.1 - 1.4e-20 73.2 0.0 3.6e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFM72424.1 - 0.0012 18.3 1.6 0.0014 18.1 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFM72424.1 - 0.027 14.4 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain EHD_N PF16880.5 KFM72425.1 - 7e-18 64.2 4.2 1.2e-17 63.5 4.2 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 KFM72425.1 - 1.3e-12 48.1 0.0 7.7e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFM72425.1 - 7.2e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KFM72425.1 - 0.013 15.8 0.1 0.024 14.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KFM72425.1 - 0.038 13.3 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Septin CLP1_P PF16575.5 KFM72425.1 - 0.069 12.9 0.0 9.7 5.9 0.0 2.8 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 KFM72425.1 - 0.079 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KFM72425.1 - 0.17 12.1 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KFM72425.1 - 0.2 11.9 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase zf-Tim10_DDP PF02953.15 KFM72426.1 - 1.8e-20 72.4 0.2 2.2e-20 72.1 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Rhodanese PF00581.20 KFM72427.1 - 3.7e-08 33.9 0.3 2.2e-07 31.4 0.0 2.5 2 1 0 2 2 2 1 Rhodanese-like domain USP8_dimer PF08969.11 KFM72428.1 - 1.3e-20 73.7 1.3 1.6e-20 73.4 1.1 1.3 1 1 0 1 1 1 1 USP8 dimerisation domain MIT PF04212.18 KFM72428.1 - 0.0029 17.7 1.5 0.0029 17.6 0.3 1.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain RVT_1 PF00078.27 KFM72429.1 - 6.2e-17 61.9 0.0 8.7e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_39 PF14090.6 KFM72432.1 - 0.057 13.2 0.1 0.22 11.3 0.0 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain zf-H2C2_2 PF13465.6 KFM72433.1 - 2.1e-108 350.3 116.7 1.5e-09 37.8 0.6 19.0 19 0 0 19 19 19 17 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72433.1 - 7.2e-82 265.5 146.3 3e-06 27.4 0.7 17.5 18 0 0 18 18 17 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72433.1 - 1.3e-63 206.1 129.1 0.00044 20.9 0.5 17.4 17 0 0 17 17 17 17 C2H2-type zinc finger zf-met PF12874.7 KFM72433.1 - 9.6e-37 124.3 120.7 0.0016 18.7 0.3 17.3 17 0 0 17 17 17 14 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM72433.1 - 2.5e-32 110.3 117.7 4.9e-05 23.2 0.6 17.9 17 1 0 17 17 17 13 C2H2-type zinc finger BolA PF01722.18 KFM72433.1 - 1e-14 54.5 25.3 0.034 14.4 0.6 10.0 2 2 3 7 7 7 4 BolA-like protein zf-C2H2_jaz PF12171.8 KFM72433.1 - 1.3e-11 44.5 97.3 0.0082 16.4 0.1 16.8 17 0 0 17 17 17 7 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM72433.1 - 1.2e-10 41.0 39.3 0.071 12.9 0.6 12.8 6 5 8 14 14 14 3 GAGA factor zf-H2C2_5 PF13909.6 KFM72433.1 - 4.3e-10 39.1 93.9 0.34 10.7 0.1 16.9 16 1 0 16 16 16 8 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM72433.1 - 9.5e-06 25.9 107.1 0.51 10.7 10.1 15.6 1 1 14 16 16 16 4 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM72433.1 - 1.3e-05 24.7 76.1 3.8 7.2 0.1 16.4 9 5 8 17 17 17 2 MYST family zinc finger domain zf-C2H2_9 PF16293.5 KFM72433.1 - 5.3e-05 23.0 70.0 2.5 8.0 0.6 16.1 8 3 9 17 17 17 1 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM72433.1 - 0.0012 19.0 70.7 0.51 10.5 5.9 8.1 1 1 8 9 9 9 4 Putative ribonucleoprotein zinc-finger pf C4 type KRTDAP PF15200.6 KFM72433.1 - 0.0094 15.7 1.4 42 4.0 0.2 6.0 6 1 0 6 6 6 0 Keratinocyte differentiation-associated ADK_lid PF05191.14 KFM72433.1 - 0.012 15.6 0.8 0.012 15.6 0.8 11.0 5 3 7 12 12 12 0 Adenylate kinase, active site lid DUF952 PF06108.12 KFM72433.1 - 0.012 15.5 5.7 69 3.5 0.0 6.1 6 2 2 8 8 7 0 Protein of unknown function (DUF952) C1_1 PF00130.22 KFM72433.1 - 0.019 14.8 82.5 1.7 8.6 0.6 14.3 8 3 8 16 16 16 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Sec23_Sec24 PF04810.15 KFM72433.1 - 0.028 14.5 63.6 0.35 11.0 0.1 15.5 9 2 8 17 17 17 0 Sec23/Sec24 zinc finger TAFII28 PF04719.14 KFM72433.1 - 0.066 13.3 0.2 94 3.2 0.0 4.6 3 2 2 5 5 5 0 hTAFII28-like protein conserved region zinc_ribbon_15 PF17032.5 KFM72433.1 - 0.14 12.9 65.0 0.61 10.9 0.7 8.9 3 2 5 9 9 9 0 zinc-ribbon family zf-C2H2_11 PF16622.5 KFM72433.1 - 0.16 11.7 0.2 0.16 11.7 0.2 14.8 16 1 1 17 17 17 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KFM72433.1 - 0.2 11.3 78.4 3.9 7.2 0.1 15.7 17 0 0 17 17 17 0 Ubiquitin-Binding Zinc Finger Tox-HNH-HHH PF15637.6 KFM72433.1 - 0.59 10.3 10.6 5 7.3 0.0 5.4 5 2 3 8 8 8 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif PknG_rubred PF16919.5 KFM72433.1 - 3.2 7.9 20.7 2.5 8.3 0.0 6.7 4 4 1 6 6 6 0 Protein kinase G rubredoxin domain zf-C2HC_2 PF13913.6 KFM72433.1 - 4.1 7.4 80.4 3.7 7.6 0.2 16.1 17 0 0 17 17 17 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFM72434.1 - 5.2e-44 146.8 29.7 1.3e-07 31.7 0.2 7.2 7 0 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72434.1 - 2.9e-28 96.7 49.8 6.5e-05 23.2 0.2 6.5 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72434.1 - 2.1e-21 74.7 47.8 0.0017 19.1 1.3 6.8 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM72434.1 - 2.9e-14 52.5 16.1 0.019 14.7 0.0 6.7 6 0 0 6 6 6 5 C2H2-type zinc-finger domain zf-met PF12874.7 KFM72434.1 - 5.9e-14 51.9 42.4 0.00044 20.6 0.7 6.4 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM72434.1 - 1.1e-07 31.6 39.8 0.034 14.2 0.4 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger GAGA PF09237.11 KFM72434.1 - 1.2e-07 31.5 12.2 0.18 11.7 0.0 5.6 1 1 5 6 6 6 3 GAGA factor BolA PF01722.18 KFM72434.1 - 4.6e-05 23.6 0.5 1.4 9.3 0.0 4.1 1 1 2 4 4 4 1 BolA-like protein zf-MYST PF17772.1 KFM72434.1 - 0.00085 18.9 31.4 0.38 10.4 0.4 6.0 2 2 4 6 6 6 3 MYST family zinc finger domain zf-C2H2_9 PF16293.5 KFM72434.1 - 0.0039 17.0 21.4 1.6 8.7 0.1 5.9 4 1 2 6 6 6 2 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM72434.1 - 0.0059 16.7 32.2 0.58 10.3 3.3 4.1 2 1 2 4 4 4 3 FYVE zinc finger C1_4 PF07975.12 KFM72434.1 - 0.009 16.2 34.6 0.052 13.8 1.5 5.0 1 1 4 5 5 5 2 TFIIH C1-like domain zf-DBF PF07535.12 KFM72434.1 - 0.039 14.1 28.6 3.2 7.9 0.5 6.4 5 1 1 6 6 6 0 DBF zinc finger zf-Sec23_Sec24 PF04810.15 KFM72434.1 - 0.083 13.0 21.3 17 5.6 0.1 6.2 5 1 1 6 6 6 0 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM72434.1 - 0.11 12.5 20.6 0.17 11.9 0.9 4.6 2 2 3 5 5 4 0 Adenylate kinase, active site lid DUF4825 PF16107.5 KFM72434.1 - 0.17 12.0 0.0 17 5.6 0.0 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4825) zf-C2H2_jaz PF12171.8 KFM72434.1 - 0.2 12.0 31.6 3.7 7.9 0.6 6.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding PHD PF00628.29 KFM72434.1 - 0.36 10.7 25.4 1.3 9.0 3.1 4.1 2 1 2 4 4 4 0 PHD-finger zf-C2H2_8 PF15909.5 KFM72434.1 - 0.4 11.0 26.5 1.2 9.5 1.4 3.8 1 1 3 4 4 4 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFM72434.1 - 0.44 11.3 24.0 0.54 11.0 2.4 3.2 1 1 0 3 3 3 0 zinc-ribbon family C5HCH PF17982.1 KFM72434.1 - 1 9.5 30.2 6.5 7.0 0.3 6.3 6 1 1 7 7 6 0 NSD Cys-His rich domain zf-FPG_IleRS PF06827.14 KFM72434.1 - 4.8 7.1 18.7 16 5.5 0.1 5.9 6 0 0 6 6 6 0 Zinc finger found in FPG and IleRS zf-HIT PF04438.16 KFM72434.1 - 6.3 6.8 30.4 8.8 6.3 1.7 6.1 6 0 0 6 6 6 0 HIT zinc finger A2L_zn_ribbon PF08792.10 KFM72434.1 - 6.7 6.5 27.4 4 7.3 0.1 6.2 6 0 0 6 6 6 0 A2L zinc ribbon domain zf-Dof PF02701.15 KFM72434.1 - 6.8 6.9 22.7 0.63 10.2 0.7 4.9 1 1 4 5 5 5 0 Dof domain, zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM72436.1 - 1.9e-16 60.0 2.2 6.5e-16 58.3 2.2 2.0 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72436.1 - 1.5e-13 50.7 0.0 2.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72436.1 - 3.3e-07 29.9 1.6 7.9e-07 28.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72436.1 - 0.0031 17.2 0.6 0.0085 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72436.1 - 0.033 14.3 0.4 0.1 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM72436.1 - 3.3 8.4 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain AA_permease_2 PF13520.6 KFM72437.1 - 1.3e-66 225.2 43.0 1.5e-66 225.0 43.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM72437.1 - 3.8e-25 88.4 33.3 6e-25 87.8 33.3 1.2 1 0 0 1 1 1 1 Amino acid permease RVT_1 PF00078.27 KFM72438.1 - 0.00022 20.8 0.0 0.00022 20.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAP PF02037.27 KFM72438.1 - 0.033 13.9 0.1 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 SAP domain RRM_5 PF13893.6 KFM72439.1 - 0.035 13.7 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFM72439.1 - 0.22 11.4 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KFM72440.1 - 5.8e-76 255.3 0.0 1.3e-75 254.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM72440.1 - 5e-45 153.8 0.0 7.6e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFM72440.1 - 7e-20 70.6 0.0 1.3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KFM72440.1 - 2.6e-06 27.0 0.0 5.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFM72440.1 - 0.0013 18.4 0.2 0.0029 17.2 0.2 1.5 1 0 0 1 1 1 1 RIO1 family UBA PF00627.31 KFM72440.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_2 PF08587.11 KFM72440.1 - 0.0067 16.5 0.4 0.022 14.9 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kdo PF06293.14 KFM72440.1 - 0.0077 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3723 PF12520.8 KFM72440.1 - 0.011 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Haspin_kinase PF12330.8 KFM72440.1 - 0.032 13.2 0.0 0.082 11.8 0.0 1.7 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFM72440.1 - 0.21 11.5 0.0 0.6 10.0 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 KFM72441.1 - 3.3e-71 240.5 10.6 3.8e-71 240.3 10.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM72441.1 - 5.1e-29 101.3 9.8 6.4e-29 101.0 9.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KFM72441.1 - 0.11 10.8 8.9 0.014 13.7 1.2 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PNMA PF14893.6 KFM72442.1 - 0.0044 16.5 1.3 0.0045 16.4 1.3 1.1 1 0 0 1 1 1 1 PNMA Sugar_tr PF00083.24 KFM72443.1 - 9.3e-28 97.3 3.6 1.2e-27 96.9 3.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM72443.1 - 0.0047 15.9 3.0 0.008 15.1 3.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TypeIII_RM_meth PF12564.8 KFM72443.1 - 0.026 14.6 0.1 0.049 13.8 0.1 1.4 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit CBFB_NFYA PF02045.15 KFM72446.1 - 9.9e-14 51.7 1.3 1.3e-13 51.3 1.3 1.2 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ANTH PF07651.16 KFM72447.1 - 2e-52 177.9 0.6 3.1e-52 177.3 0.6 1.3 1 0 0 1 1 1 1 ANTH domain KCNQ_channel PF03520.14 KFM72448.1 - 7.4e-34 117.3 4.1 3e-33 115.3 4.1 1.9 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 KFM72448.1 - 1.6e-27 96.3 12.7 2.1e-27 95.9 12.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFM72448.1 - 1e-13 51.0 5.1 3.2e-13 49.4 5.1 1.9 1 0 0 1 1 1 1 Ion channel DHC_N1 PF08385.12 KFM72448.1 - 0.018 13.7 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Fib_alpha PF08702.10 KFM72448.1 - 0.14 12.3 0.5 0.34 11.1 0.5 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Adaptin_N PF01602.20 KFM72450.1 - 7.3e-62 209.6 0.1 8.1e-62 209.5 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFM72450.1 - 4.6e-10 39.8 0.0 7.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM72450.1 - 0.00019 21.8 0.0 0.065 13.6 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KFM72450.1 - 0.0006 19.8 0.0 0.06 13.6 0.0 2.9 3 0 0 3 3 3 1 HEAT repeat RTP1_C1 PF10363.9 KFM72450.1 - 0.021 15.0 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 PPTA PF01239.22 KFM72450.1 - 0.16 11.7 0.9 14 5.5 0.1 2.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat EMP70 PF02990.16 KFM72451.1 - 0.16 10.6 9.8 0.24 10.0 9.8 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 DDE_3 PF13358.6 KFM72453.1 - 4.8e-16 58.8 0.1 5.7e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72453.1 - 7.3e-16 58.2 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72453.1 - 0.00065 20.3 1.4 0.00065 20.3 1.4 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72453.1 - 0.0023 17.7 0.1 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72453.1 - 0.013 15.6 0.1 0.064 13.4 0.1 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 KFM72453.1 - 0.085 12.9 0.2 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM72453.1 - 0.15 12.1 4.2 0.086 12.9 1.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM72454.1 - 7.4e-17 61.4 1.6 6.6e-16 58.3 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72454.1 - 1.3e-13 51.0 0.0 2.7e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72454.1 - 1.8e-07 30.8 1.4 7.9e-07 28.7 0.2 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72454.1 - 0.0027 17.5 1.0 0.0086 15.9 0.6 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72454.1 - 0.015 15.4 0.4 0.1 12.7 0.4 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM72454.1 - 2.2 8.9 15.6 0.14 12.8 2.0 3.4 2 1 1 3 3 3 0 Homeodomain-like domain Melibiase_2 PF16499.5 KFM72456.1 - 2e-117 391.4 0.9 2.7e-117 391.0 0.9 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 KFM72456.1 - 9.3e-07 29.0 0.0 2.9e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 KFM72456.1 - 7.4e-05 22.8 0.0 0.00033 20.6 0.0 2.1 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFM72456.1 - 0.00043 19.3 0.0 0.00082 18.4 0.0 1.4 2 0 0 2 2 2 1 Melibiase Melibiase_2 PF16499.5 KFM72458.1 - 7.4e-13 48.3 0.4 8.1e-13 48.2 0.4 1.1 1 0 0 1 1 1 1 Alpha galactosidase A YL1 PF05764.13 KFM72459.1 - 3.1e-29 102.8 37.0 3.5e-29 102.7 37.0 1.0 1 0 0 1 1 1 1 YL1 nuclear protein TIR_2 PF13676.6 KFM72461.1 - 2e-09 38.1 0.0 2.1e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 TIR domain DUF4062 PF13271.6 KFM72461.1 - 0.014 15.8 0.0 0.014 15.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) TIR PF01582.20 KFM72461.1 - 0.027 14.3 0.0 0.029 14.2 0.0 1.0 1 0 0 1 1 1 0 TIR domain RRM_1 PF00076.22 KFM72463.1 - 1.8e-13 50.1 0.0 2.8e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Somatomedin_B PF01033.17 KFM72465.1 - 0.012 16.0 13.0 0.012 16.0 13.0 2.6 2 0 0 2 2 2 0 Somatomedin B domain FTZ PF03867.14 KFM72466.1 - 4.8 6.6 9.5 0.74 9.3 5.3 1.7 1 1 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region NAD_kinase PF01513.21 KFM72467.1 - 2.3e-67 227.2 0.0 2.8e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFM72467.1 - 0.028 14.1 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain USP7_ICP0_bdg PF12436.8 KFM72468.1 - 6.2e-76 254.9 0.0 1.4e-75 253.7 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KFM72468.1 - 6.2e-70 235.1 0.9 1.9e-69 233.5 0.5 2.1 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KFM72468.1 - 1.2e-51 175.7 0.3 1.9e-51 175.1 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM72468.1 - 5.9e-21 75.4 0.0 2e-20 73.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KFM72468.1 - 1e-19 70.8 0.5 3.1e-18 66.0 0.0 2.9 3 0 0 3 3 3 1 MATH domain Peptidase_C98 PF15499.6 KFM72468.1 - 0.024 14.1 0.1 6.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase COMPASS-Shg1 PF05205.12 KFM72470.1 - 5.3e-16 59.2 0.1 5.3e-16 59.2 0.1 3.9 3 1 1 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component shg1 PRIMA1 PF16101.5 KFM72470.1 - 0.066 13.2 5.1 0.25 11.4 5.1 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Sec1 PF00995.23 KFM72471.1 - 8.2e-78 263.1 0.0 9.1e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ParA PF10609.9 KFM72472.1 - 2.6e-99 331.7 1.4 3.1e-99 331.4 1.4 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFM72472.1 - 2.4e-10 40.6 0.0 3.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KFM72472.1 - 5.3e-09 35.9 1.4 8.6e-08 31.9 1.4 2.3 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 KFM72472.1 - 2.4e-06 27.6 4.0 4.5e-06 26.7 1.3 2.1 1 1 0 2 2 2 1 AAA domain MipZ PF09140.11 KFM72472.1 - 4.6e-06 26.1 0.0 7.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KFM72472.1 - 0.00029 20.1 2.3 0.00079 18.7 0.7 2.2 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 KFM72472.1 - 0.04 13.5 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 KFM72472.1 - 0.061 12.6 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 VirC1 protein PhoH PF02562.16 KFM72472.1 - 0.17 11.3 0.1 0.63 9.5 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein MIEAP PF16026.5 KFM72475.1 - 1.1e-38 133.5 0.0 1.2e-38 133.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondria-eating protein Dpy-30 PF05186.13 KFM72475.1 - 0.14 11.9 0.3 10 5.9 0.0 2.6 2 1 0 2 2 2 0 Dpy-30 motif MIEAP PF16026.5 KFM72476.1 - 2.3e-11 44.3 0.3 3.4e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Mitochondria-eating protein Taxilin PF09728.9 KFM72476.1 - 0.022 13.9 0.8 0.032 13.4 0.8 1.3 1 1 0 1 1 1 0 Myosin-like coiled-coil protein EMP24_GP25L PF01105.24 KFM72476.1 - 0.051 13.5 0.8 0.068 13.1 0.8 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF745 PF05335.13 KFM72476.1 - 0.12 12.0 0.6 0.18 11.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Imm5 PF14423.6 KFM72477.1 - 0.037 14.3 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Immunity protein Imm5 DUF2383 PF09537.10 KFM72477.1 - 0.039 14.3 0.3 0.57 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) DUF3926 PF13080.6 KFM72477.1 - 0.22 11.5 2.9 15 5.6 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) HTH_Tnp_Tc3_2 PF01498.18 KFM72478.1 - 1.8e-16 60.1 2.6 4.6e-16 58.8 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72478.1 - 9.9e-14 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KFM72479.1 - 1.6e-17 63.7 0.1 2.6e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM72479.1 - 3.8e-12 46.0 0.3 8.4e-12 44.9 0.3 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM72479.1 - 0.0034 17.1 0.0 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3372 PF11852.8 KFM72479.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) HTH_Tnp_Tc3_2 PF01498.18 KFM72480.1 - 2.4e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72480.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ig_2 PF13895.6 KFM72481.1 - 1.1e-05 25.7 0.0 1.1e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM72481.1 - 0.0075 16.8 0.0 0.0078 16.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM72481.1 - 0.013 15.6 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin V-set domain ig PF00047.25 KFM72481.1 - 0.027 14.7 0.0 0.032 14.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFM72481.1 - 0.077 13.1 0.0 0.079 13.0 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain Peptidase_M13_N PF05649.13 KFM72482.1 - 4.6e-10 39.7 0.0 4.9e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM72483.1 - 5.9e-33 115.1 0.8 7e-33 114.8 0.8 1.0 1 0 0 1 1 1 1 Peptidase family M13 TIL PF01826.17 KFM72484.1 - 1.1e-12 48.0 45.0 3.8e-10 39.9 15.3 2.5 2 0 0 2 2 2 2 Trypsin Inhibitor like cysteine rich domain WD40 PF00400.32 KFM72486.1 - 1.6e-05 25.5 20.1 0.02 15.7 0.2 7.5 7 1 1 8 8 8 3 WD domain, G-beta repeat Rav1p_C PF12234.8 KFM72486.1 - 0.03 12.7 0.2 0.72 8.2 0.1 2.5 2 1 0 2 2 2 0 RAVE protein 1 C terminal Rav1p_C PF12234.8 KFM72487.1 - 1.3e-72 245.2 2.0 1.2e-63 215.6 0.7 3.5 3 0 0 3 3 3 3 RAVE protein 1 C terminal WD40 PF00400.32 KFM72487.1 - 4.3e-09 36.9 1.3 4.1 8.4 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM72487.1 - 0.0027 18.0 0.0 0.17 12.2 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PTE PF02126.18 KFM72487.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotriesterase family A_deaminase PF00962.22 KFM72488.1 - 7.6e-41 140.5 0.0 8.6e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KFM72488.1 - 0.027 13.8 0.0 0.052 12.8 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase family HTH_Tnp_Tc3_2 PF01498.18 KFM72491.1 - 3.9e-16 59.1 0.9 7.7e-16 58.1 0.9 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72491.1 - 1.8e-14 53.7 0.0 2.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM72491.1 - 0.0027 18.3 0.7 0.0027 18.3 0.7 2.9 3 0 0 3 3 3 1 Homeodomain-like domain DUF2525 PF10733.9 KFM72492.1 - 0.03 14.6 0.1 0.061 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) HTH_11 PF08279.12 KFM72492.1 - 0.046 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 HTH domain ANT PF03374.14 KFM72492.1 - 0.095 13.0 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain HTH_24 PF13412.6 KFM72492.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 KFM72492.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain LacI PF00356.21 KFM72492.1 - 0.14 11.9 0.2 1.1 9.2 0.2 2.2 1 1 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_Tnp_Tc3_2 PF01498.18 KFM72493.1 - 2.4e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72493.1 - 9.8e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72494.1 - 1.9e-16 60.0 2.2 6.5e-16 58.4 2.2 2.0 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72494.1 - 1.4e-13 50.8 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72494.1 - 7.8e-07 28.8 0.2 7.8e-07 28.8 0.2 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72494.1 - 0.0027 17.4 3.0 0.0084 15.9 0.6 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM72494.1 - 0.079 12.8 1.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Tc3 transposase 2-Hacid_dh_C PF02826.19 KFM72495.1 - 9.5e-58 194.5 0.0 1.5e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFM72495.1 - 1e-32 112.6 0.0 1.2e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFM72495.1 - 3.7e-06 27.2 0.1 6.3e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFM72495.1 - 0.00013 22.5 0.1 0.00026 21.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KFM72495.1 - 0.001 19.2 0.2 0.0025 17.9 0.1 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 KFM72495.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3320 PF11784.8 KFM72495.1 - 0.073 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) TrkA_N PF02254.18 KFM72495.1 - 0.079 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain RT_RNaseH PF17917.1 KFM72496.1 - 1.2e-30 105.9 0.7 3.7e-30 104.3 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KFM72496.1 - 4.1e-30 103.8 0.8 1.3e-29 102.2 0.1 2.3 3 0 0 3 3 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM72496.1 - 2e-22 79.8 0.1 4.7e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KFM72496.1 - 1.2e-15 57.3 0.2 3.4e-15 55.9 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 KFM72496.1 - 1.1e-12 48.4 0.0 1.6e-08 35.1 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KFM72496.1 - 3.8e-09 37.0 0.0 1e-05 26.0 0.0 3.1 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 KFM72496.1 - 3.7e-08 33.1 11.8 7.4e-05 22.6 0.7 3.1 3 0 0 3 3 3 2 Zinc knuckle RVP_2 PF08284.11 KFM72496.1 - 0.001 18.8 0.0 0.51 10.1 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease zf-CCHC_4 PF14392.6 KFM72496.1 - 0.079 12.7 6.3 0.56 10.0 0.3 2.8 2 0 0 2 2 2 0 Zinc knuckle DUF3990 PF13151.6 KFM72496.1 - 0.28 10.9 3.3 0.77 9.4 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) CDC45 PF02724.14 KFM72496.1 - 0.72 8.1 9.0 1.2 7.3 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM72497.1 - 5.7e-13 48.9 12.1 3.8e-12 46.3 2.5 2.7 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM72497.1 - 3.1e-11 43.2 0.0 7.5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM72497.1 - 0.0023 18.5 19.3 0.025 15.2 0.5 4.6 4 1 1 5 5 5 2 Homeodomain-like domain HTH_7 PF02796.15 KFM72497.1 - 0.028 14.5 0.6 9.7 6.4 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_24 PF13412.6 KFM72497.1 - 0.15 11.7 0.8 1.2 8.7 0.0 2.6 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding Troponin PF00992.20 KFM72497.1 - 0.64 10.3 2.0 0.77 10.1 1.0 1.6 2 0 0 2 2 2 0 Troponin DDE_3 PF13358.6 KFM72498.1 - 6.1e-16 58.5 0.1 6.6e-15 55.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72498.1 - 8.2e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72498.1 - 0.00078 20.0 1.5 0.00078 20.0 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72498.1 - 0.0044 16.8 0.1 0.18 11.6 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM72498.1 - 0.038 14.0 0.4 0.038 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM72504.1 - 3.5e-14 52.8 0.9 6.3e-14 52.0 0.2 1.7 2 0 0 2 2 2 1 Transposase Zip PF02535.22 KFM72505.1 - 5e-30 104.8 5.4 9.1e-30 104.0 5.4 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter PDR_CDR PF06422.12 KFM72505.1 - 0.11 12.4 0.9 12 5.9 0.0 2.9 3 0 0 3 3 3 0 CDR ABC transporter DUF2062 PF09835.9 KFM72505.1 - 5.5 6.8 10.2 0.14 12.0 2.9 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) CRAL_TRIO PF00650.20 KFM72507.1 - 1.3e-29 102.9 0.0 3.3e-29 101.6 0.0 1.6 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM72507.1 - 8e-08 32.3 0.3 2.5e-07 30.7 0.3 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM72507.1 - 0.00045 20.4 0.5 0.0009 19.4 0.4 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain P4Ha_N PF08336.11 KFM72508.1 - 3.9e-40 137.0 1.4 7.8e-40 136.0 1.4 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SPO22 PF08631.10 KFM72508.1 - 0.0048 16.4 1.1 0.055 13.0 0.1 2.6 2 1 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like 2OG-FeII_Oxy_3 PF13640.6 KFM72508.1 - 0.031 15.1 0.0 0.079 13.9 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 KFM72508.1 - 0.053 13.6 0.2 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1910 PF08928.10 KFM72508.1 - 0.31 11.0 2.4 0.28 11.2 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) CENP-Q PF13094.6 KFM72508.1 - 0.81 9.9 3.3 2.6 8.2 3.3 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HLH PF00010.26 KFM72510.1 - 8e-17 60.9 2.2 2e-16 59.7 2.1 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFM72510.1 - 3.1e-07 30.6 0.1 1.9e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFM72510.1 - 3.5e-07 30.2 0.1 1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KFM72510.1 - 7.4e-07 29.4 0.0 3.7e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KFM72510.1 - 0.002 18.2 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain HAUS-augmin3 PF14932.6 KFM72510.1 - 0.035 13.7 0.3 0.045 13.3 0.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 PAS_2 PF08446.11 KFM72510.1 - 0.045 14.4 0.0 0.095 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold HORMA PF02301.18 KFM72511.1 - 2.2e-18 66.6 0.5 4.4e-18 65.6 0.5 1.5 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 KFM72511.1 - 0.04 13.8 0.2 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial HORMA domain 2 HTH_Tnp_Tc3_2 PF01498.18 KFM72512.1 - 4e-16 59.0 3.4 5.2e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72512.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72512.1 - 1.1e-07 31.5 0.7 5.2e-07 29.3 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72512.1 - 0.0025 17.5 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72512.1 - 0.028 14.6 0.4 0.083 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM72512.1 - 1.1 9.9 14.8 0.1 13.2 1.8 3.3 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM72513.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72513.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ig_2 PF13895.6 KFM72514.1 - 1.8e-08 34.6 0.0 0.002 18.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFM72514.1 - 3.1e-06 27.1 0.1 1e-05 25.5 0.1 2.0 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM72514.1 - 3.8e-06 27.4 0.5 0.019 15.5 0.0 3.2 2 1 1 3 3 3 2 Immunoglobulin domain Ses_B PF17046.5 KFM72514.1 - 0.07 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein ig PF00047.25 KFM72514.1 - 0.1 12.8 0.1 17 5.7 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin domain Ig_2 PF13895.6 KFM72515.1 - 1.1e-05 25.7 0.0 1.1e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM72515.1 - 0.0044 17.6 0.0 0.0046 17.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM72515.1 - 0.017 15.3 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin V-set domain ig PF00047.25 KFM72515.1 - 0.019 15.1 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFM72515.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain HTH_Tnp_Tc3_2 PF01498.18 KFM72516.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72516.1 - 9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72517.1 - 2.8e-16 59.5 2.2 5.1e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72517.1 - 1.2e-13 51.0 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RVP PF00077.20 KFM72518.1 - 0.00023 21.4 0.0 0.00048 20.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 KFM72518.1 - 0.00035 20.5 0.6 0.0011 19.0 0.6 1.9 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 KFM72518.1 - 0.069 13.7 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_3 PF13358.6 KFM72519.1 - 3.2e-15 56.1 0.1 3.6e-14 52.7 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72519.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM72520.1 - 2e-16 60.0 2.2 4.6e-16 58.8 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72520.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72522.1 - 1.5e-17 63.6 1.3 3.2e-17 62.5 1.3 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72522.1 - 2.8e-14 53.1 0.0 4.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM72522.1 - 5.6e-05 23.7 2.2 5.6e-05 23.7 2.2 2.9 3 0 0 3 3 3 1 Homeodomain-like domain MarR_2 PF12802.7 KFM72522.1 - 0.011 15.6 0.4 0.78 9.7 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_3 PF01381.22 KFM72522.1 - 0.012 15.7 0.4 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_23 PF13384.6 KFM72522.1 - 0.023 14.5 0.6 1.1 9.2 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 KFM72522.1 - 0.025 14.7 0.5 0.85 9.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM72522.1 - 0.068 13.2 1.2 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain PAX PF00292.18 KFM72522.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 'Paired box' domain HTH_Tnp_Tc3_2 PF01498.18 KFM72523.1 - 1.4e-16 60.5 2.0 4e-16 59.0 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72523.1 - 8.3e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM72524.1 - 2.8e-10 40.1 0.0 3.5e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72525.1 - 2.7e-16 59.6 2.2 4.9e-16 58.7 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72525.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72526.1 - 2e-16 60.0 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72526.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_28 PF13521.6 KFM72527.1 - 0.0016 18.7 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 KFM72527.1 - 0.0016 17.7 0.0 0.0016 17.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 KTI12 PF08433.10 KFM72527.1 - 0.0053 16.2 0.0 0.0058 16.1 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Pox_A32 PF04665.12 KFM72527.1 - 0.15 11.5 0.0 0.15 11.5 0.0 1.0 1 0 0 1 1 1 0 Poxvirus A32 protein DUF2812 PF11193.8 KFM72527.1 - 0.18 12.1 0.0 0.18 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) NTPase_1 PF03266.15 KFM72527.1 - 0.19 11.6 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 KFM72527.1 - 0.24 10.4 0.0 0.25 10.3 0.0 1.0 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 KFM72528.1 - 2.8e-08 34.2 0.1 5.3e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain Phospholip_A2_2 PF05826.12 KFM72530.1 - 3e-36 123.5 3.3 6.9e-36 122.4 3.3 1.6 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 KFM72530.1 - 0.0025 18.3 10.4 0.27 11.7 1.3 2.7 1 1 1 2 2 2 2 Phospholipase A2 Polbeta PF18765.1 KFM72533.1 - 0.013 15.6 0.0 0.036 14.2 0.0 1.8 1 1 1 2 2 2 0 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KFM72533.1 - 0.021 15.1 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Y_phosphatase PF00102.27 KFM72534.1 - 5e-164 543.4 0.8 2e-81 273.0 0.1 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFM72534.1 - 7e-91 298.7 29.7 7e-18 64.8 0.1 7.8 7 0 0 7 7 7 7 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM72534.1 - 3.7e-18 65.9 21.0 0.011 16.3 0.1 8.1 7 0 0 7 7 7 7 Purple acid Phosphatase, N-terminal domain DSPc PF00782.20 KFM72534.1 - 7e-09 35.6 0.0 0.0027 17.5 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM72534.1 - 1.6e-07 31.6 0.0 0.018 15.0 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM72534.1 - 5.5e-05 23.3 0.1 0.054 13.6 0.0 2.9 3 0 0 3 3 3 2 Inositol hexakisphosphate fn3_2 PF16893.5 KFM72534.1 - 0.00016 21.8 4.0 0.45 10.7 0.0 5.4 6 0 0 6 6 6 1 Fibronectin type III domain Arylsulfotran_N PF17425.2 KFM72534.1 - 0.0019 18.2 1.1 0.054 13.5 0.1 2.7 2 0 0 2 2 2 1 Arylsulfotransferase Ig-like domain DUF2369 PF10179.9 KFM72534.1 - 0.0061 16.9 0.0 5.5 7.4 0.0 4.0 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2369) DUF3377 PF11857.8 KFM72534.1 - 0.015 15.2 0.2 0.041 13.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) SusE PF14292.6 KFM72534.1 - 0.025 14.8 4.8 4.8 7.5 0.0 4.6 5 0 0 5 5 5 0 SusE outer membrane protein TMEM154 PF15102.6 KFM72534.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family HTH_Tnp_Tc3_2 PF01498.18 KFM72535.1 - 4.4e-16 58.9 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72535.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72535.1 - 2e-07 30.7 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72535.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72535.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RPAP1_C PF08620.10 KFM72538.1 - 6.5e-26 90.2 0.2 1.4e-25 89.2 0.2 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KFM72538.1 - 4.3e-12 45.6 3.9 4.7e-12 45.5 0.6 2.6 2 0 0 2 2 2 1 RPAP1-like, N-terminal YopX PF09643.10 KFM72538.1 - 0.42 10.7 11.3 0.43 10.6 1.1 2.8 1 1 1 2 2 2 0 YopX protein WD40 PF00400.32 KFM72539.1 - 1.5e-32 111.1 12.3 1.7e-08 35.0 0.0 10.6 13 0 0 13 13 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM72539.1 - 6.4e-24 84.1 0.0 0.00025 21.3 0.0 9.3 2 2 7 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KFM72539.1 - 1.9e-23 82.8 0.1 3.2e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KFM72539.1 - 5.7e-13 48.5 1.9 0.0054 15.7 0.0 5.2 3 3 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFM72539.1 - 2.2e-10 40.7 1.0 0.0011 18.9 0.1 5.6 2 2 4 6 6 6 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFM72539.1 - 1.3e-05 24.7 1.6 0.012 14.9 0.1 4.2 2 1 0 2 2 2 1 WD40-like domain Utp13 PF08625.11 KFM72539.1 - 0.0017 18.2 0.4 0.0047 16.8 0.4 1.7 1 1 0 1 1 1 1 Utp13 specific WD40 associated domain PD40 PF07676.12 KFM72539.1 - 0.0041 17.0 0.0 62 3.7 0.0 5.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 KFM72539.1 - 0.0096 15.0 0.1 0.5 9.3 0.0 3.0 2 1 0 3 3 3 1 Coatomer WD associated region Utp21 PF04192.12 KFM72539.1 - 0.016 14.7 0.2 0.016 14.7 0.2 1.8 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain DUF1513 PF07433.11 KFM72539.1 - 0.018 14.1 0.1 0.063 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) RAB3GAP2_N PF14655.6 KFM72539.1 - 0.043 13.1 0.0 37 3.4 0.0 4.4 4 1 1 5 5 5 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DPPIV_N PF00930.21 KFM72539.1 - 0.12 11.2 0.0 0.54 8.9 0.0 2.3 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region UTP15_C PF09384.10 KFM72539.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 UTP15 C terminal Katanin_con80 PF13925.6 KFM72539.1 - 0.16 12.0 0.1 0.26 11.3 0.1 1.3 1 0 0 1 1 1 0 con80 domain of Katanin Arrestin_N PF00339.29 KFM72540.1 - 0.0026 17.8 0.0 0.0026 17.8 0.0 1.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Cullin_binding PF03556.15 KFM72541.1 - 0.13 12.7 5.5 3 8.3 0.6 2.3 1 1 0 2 2 2 0 Cullin binding LSM PF01423.22 KFM72542.1 - 4.8e-20 71.0 0.2 6.3e-20 70.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain Glutaredoxin PF00462.24 KFM72542.1 - 0.0058 16.8 0.1 0.012 15.8 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin DUF150_C PF17384.2 KFM72542.1 - 0.063 13.4 0.3 0.11 12.6 0.3 1.4 1 1 0 1 1 1 0 RimP C-terminal SH3 domain AAA_lid_1 PF17857.1 KFM72542.1 - 0.14 12.4 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA+ lid domain SpoU_methylase PF00588.19 KFM72543.1 - 6.6e-32 110.6 0.0 1e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KFM72543.1 - 6.5e-10 39.2 0.0 2.5e-09 37.3 0.0 2.0 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF4969 PF16339.5 KFM72543.1 - 0.13 12.6 1.0 2.3 8.6 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4969) GTP_EFTU PF00009.27 KFM72544.1 - 3.1e-62 209.6 0.1 5.1e-62 208.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KFM72544.1 - 2.8e-25 88.2 0.0 8.5e-25 86.6 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFM72544.1 - 3.7e-22 78.2 0.0 7e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 KFM72544.1 - 1.8e-15 56.8 0.1 4.5e-15 55.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 KFM72544.1 - 3e-07 30.3 0.0 6.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 KFM72544.1 - 2.8e-05 24.4 0.0 0.00017 21.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM72544.1 - 7.2e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM72544.1 - 0.083 12.4 0.1 0.3 10.6 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KFM72544.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ank_2 PF12796.7 KFM72545.1 - 2.8e-41 140.0 3.6 1.3e-14 54.5 0.0 5.5 4 3 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM72545.1 - 1.5e-40 137.0 6.1 4.5e-12 46.2 0.1 7.6 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM72545.1 - 4e-38 125.1 11.3 0.00036 20.8 0.0 9.7 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 KFM72545.1 - 5.6e-37 124.6 14.8 0.0003 21.1 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KFM72545.1 - 1.1e-24 86.2 11.2 2e-06 27.9 0.0 7.2 5 2 3 8 8 8 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFM72545.1 - 6.7e-07 29.6 0.0 1.9e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 SOCS box HEAT PF02985.22 KFM72547.1 - 1.5e-17 62.1 6.4 0.0016 18.5 0.0 7.2 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 KFM72547.1 - 1.1e-08 35.4 0.5 1.4 9.4 0.3 5.0 4 1 0 5 5 5 4 HEAT repeats Cnd1 PF12717.7 KFM72547.1 - 4.8e-05 23.5 2.8 0.63 10.1 0.1 4.0 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 WRNPLPNID PF15017.6 KFM72547.1 - 0.001 19.9 0.2 0.001 19.9 0.2 2.6 2 1 1 3 3 3 1 Putative WW-binding domain and destruction box COBRA1 PF06209.13 KFM72547.1 - 0.002 17.1 0.0 0.0046 15.9 0.0 1.5 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Telomere_reg-2 PF10193.9 KFM72547.1 - 0.022 15.2 1.4 0.24 11.9 0.2 2.5 2 0 0 2 2 2 0 Telomere length regulation protein CLASP_N PF12348.8 KFM72547.1 - 0.028 14.0 0.1 6 6.3 0.0 3.0 3 0 0 3 3 3 0 CLASP N terminal Sulfotransfer_1 PF00685.27 KFM72548.1 - 6.2e-53 180.0 0.6 7.8e-53 179.7 0.6 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM72548.1 - 7.6e-09 36.3 0.0 3.5e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family DUF4371 PF14291.6 KFM72551.1 - 1.8e-30 106.3 0.5 3.5e-30 105.4 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM72551.1 - 2e-09 37.1 0.2 8.5e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM72551.1 - 0.049 12.6 7.6 0.059 12.3 0.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MAT1 PF06391.13 KFM72551.1 - 3.1 7.6 7.7 2.7 7.7 2.0 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Exonuc_VII_L PF02601.15 KFM72551.1 - 5.7 6.4 7.3 8.3 5.9 1.4 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Cyclin_N PF00134.23 KFM72552.1 - 0.023 14.5 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFM72553.1 - 1e-16 61.1 0.0 1.3e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain DRIM PF07539.12 KFM72554.1 - 1.2e-15 56.9 0.1 1.2e-15 56.9 0.1 5.2 6 2 1 7 7 7 1 Down-regulated in metastasis DUF4042 PF13251.6 KFM72554.1 - 2.6e-05 24.0 2.7 0.0021 17.8 0.0 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT PF02985.22 KFM72554.1 - 5.7e-05 23.0 1.0 0.08 13.2 0.2 4.7 5 0 0 5 5 5 1 HEAT repeat Erf4 PF10256.9 KFM72554.1 - 0.3 11.2 4.9 6.3 6.9 0.0 4.9 4 3 1 5 5 5 0 Golgin subfamily A member 7/ERF4 family SurA_N_2 PF13623.6 KFM72554.1 - 0.33 10.8 0.0 0.33 10.8 0.0 2.9 4 0 0 4 4 4 0 SurA N-terminal domain MMS19_N PF14500.6 KFM72554.1 - 2.4 7.7 13.4 0.33 10.5 1.4 4.6 3 3 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II DRIM PF07539.12 KFM72555.1 - 2e-114 383.2 7.7 2e-114 383.2 7.7 2.2 2 0 0 2 2 2 2 Down-regulated in metastasis Myc_N PF01056.18 KFM72555.1 - 0.14 12.0 6.7 0.28 11.0 6.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region NYD-SP28 PF14772.6 KFM72556.1 - 0.024 14.7 0.5 0.05 13.7 0.1 1.7 2 0 0 2 2 2 0 Sperm tail Cnd3 PF12719.7 KFM72556.1 - 0.049 12.8 3.1 2.9 7.0 1.8 2.1 1 1 1 2 2 2 0 Nuclear condensing complex subunits, C-term domain HTH_Tnp_Tc3_2 PF01498.18 KFM72557.1 - 5.3e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72557.1 - 5.3e-12 45.7 0.0 9.1e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72557.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72557.1 - 0.0027 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72557.1 - 2.2 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Bestrophin PF01062.21 KFM72558.1 - 1.3e-105 353.1 3.2 1.6e-105 352.7 3.2 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 KFM72559.1 - 3.6e-67 226.8 0.3 5.3e-67 226.3 0.3 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PH PF00169.29 KFM72561.1 - 7.5e-09 36.1 0.0 1.2e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 PH domain Laminin_G_3 PF13385.6 KFM72561.1 - 0.021 15.0 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Anillin PF08174.11 KFM72562.1 - 6.1e-20 72.1 0.4 6.8e-20 71.9 0.4 1.0 1 0 0 1 1 1 1 Cell division protein anillin HPS3_N PF14761.6 KFM72563.1 - 6.9e-61 205.5 3.0 9e-61 205.1 3.0 1.1 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 HPS3_Mid PF14762.6 KFM72563.1 - 1.5e-21 76.6 0.3 2.8e-21 75.7 0.3 1.4 1 1 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region UNC80 PF15778.5 KFM72564.1 - 2.3e-08 33.9 0.4 2.4e-08 33.8 0.4 1.0 1 0 0 1 1 1 1 Cation channel complex component UNC80 UNC80 PF15778.5 KFM72565.1 - 1e-45 155.6 0.1 1.3e-45 155.3 0.1 1.1 1 0 0 1 1 1 1 Cation channel complex component UNC80 Fe_dep_repr_C PF02742.15 KFM72568.1 - 0.088 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain UXS1_N PF11803.8 KFM72572.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal Pinin_SDK_memA PF04696.13 KFM72573.1 - 0.1 12.7 6.7 0.19 11.8 6.7 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Lactate_perm PF02652.14 KFM72573.1 - 0.23 10.1 0.0 0.31 9.7 0.0 1.1 1 0 0 1 1 1 0 L-lactate permease TetR_C_18 PF17923.1 KFM72576.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RVT_1 PF00078.27 KFM72577.1 - 0.0069 15.9 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TSC22 PF01166.18 KFM72579.1 - 1.8e-27 95.4 6.4 1.8e-27 95.4 6.4 1.7 2 0 0 2 2 2 1 TSC-22/dip/bun family YabA PF06156.13 KFM72579.1 - 0.00057 20.5 2.2 0.0023 18.6 1.5 1.9 2 0 0 2 2 2 1 Initiation control protein YabA CCDC106 PF15794.5 KFM72579.1 - 0.0047 16.7 0.1 0.009 15.8 0.1 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 TBK1_CCD1 PF18394.1 KFM72579.1 - 0.013 15.1 0.2 0.019 14.6 0.2 1.2 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 Shugoshin_N PF07558.11 KFM72579.1 - 0.035 14.0 1.4 0.062 13.2 1.4 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Herpes_UL6 PF01763.16 KFM72579.1 - 0.052 12.1 0.3 0.065 11.8 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like LUC7 PF03194.15 KFM72579.1 - 0.16 11.6 3.3 0.35 10.5 3.3 1.4 1 1 0 1 1 1 0 LUC7 N_terminus DivIC PF04977.15 KFM72579.1 - 0.21 11.4 1.6 0.38 10.6 1.0 1.7 1 1 0 1 1 1 0 Septum formation initiator Fzo_mitofusin PF04799.13 KFM72579.1 - 0.72 9.4 4.7 0.26 10.8 2.0 1.6 2 0 0 2 2 2 0 fzo-like conserved region ZapB PF06005.12 KFM72579.1 - 1.2 9.7 8.9 0.46 11.0 5.9 1.9 2 1 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 KFM72579.1 - 1.2 9.2 4.6 1.4 9.0 2.8 2.0 2 1 0 2 2 2 0 Basic region leucine zipper DDE_3 PF13358.6 KFM72580.1 - 4e-16 59.1 0.1 4.8e-15 55.6 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72580.1 - 7.6e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72580.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72580.1 - 0.0014 18.4 0.0 0.058 13.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72580.1 - 0.012 15.8 0.1 0.046 13.8 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM72580.1 - 0.022 14.8 2.1 0.031 14.3 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM72580.1 - 0.026 14.4 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase zf-BED PF02892.15 KFM72581.1 - 0.0027 17.7 1.8 0.0058 16.6 1.8 1.5 1 0 0 1 1 1 1 BED zinc finger zf-H2C2_2 PF13465.6 KFM72581.1 - 0.025 15.0 1.6 0.067 13.7 1.6 1.8 1 0 0 1 1 1 0 Zinc-finger double domain Ycf54 PF10674.9 KFM72581.1 - 0.029 14.6 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) DUF2666 PF10869.8 KFM72581.1 - 0.067 13.4 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) zf-C2H2 PF00096.26 KFM72581.1 - 0.077 13.5 1.0 0.077 13.5 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KFM72581.1 - 0.12 12.3 2.7 0.27 11.2 2.7 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Filament PF00038.21 KFM72581.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Intermediate filament protein adh_short PF00106.25 KFM72582.1 - 5.2e-34 117.4 0.0 2.8e-33 115.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM72582.1 - 2.6e-21 76.3 0.0 7.4e-21 74.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM72582.1 - 5.5e-10 39.4 0.0 8.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM72582.1 - 5e-06 26.2 0.0 7.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM72582.1 - 0.00016 21.2 0.0 0.00029 20.4 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Hpr_kinase_C PF07475.12 KFM72582.1 - 0.032 13.7 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain 2-Hacid_dh_C PF02826.19 KFM72582.1 - 0.053 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 KFM72582.1 - 0.056 11.9 0.1 1.8 6.8 0.0 2.1 1 1 1 2 2 2 0 Flavin-binding monooxygenase-like DUF3719 PF12516.8 KFM72587.1 - 8.9e-10 38.1 0.0 1.4e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3719) DUF759 PF05537.11 KFM72587.1 - 0.1 11.5 0.6 0.16 10.8 0.6 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) DDE_3 PF13358.6 KFM72588.1 - 3.1e-05 23.8 0.0 4.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 KFM72589.1 - 0.00011 21.7 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1951 PF09188.10 KFM72589.1 - 0.11 12.5 0.3 0.12 12.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) Ion_trans_2 PF07885.16 KFM72590.1 - 1.5e-19 69.7 2.6 2.5e-19 69.0 2.6 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFM72590.1 - 0.017 14.4 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein DDE_3 PF13358.6 KFM72591.1 - 1.7e-10 40.9 0.0 1.9e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease V-set PF07686.17 KFM72592.1 - 2.6e-06 27.6 0.0 3.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM72592.1 - 2.8e-05 24.6 0.1 0.00018 22.0 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 KFM72592.1 - 0.00022 20.7 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM72592.1 - 0.00052 20.1 0.1 0.0012 19.0 0.0 1.9 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM72592.1 - 0.00078 19.5 0.0 0.0025 17.8 0.0 1.9 1 1 1 2 2 2 1 Immunoglobulin I-set domain Izumo-Ig PF16706.5 KFM72592.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.4 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 KFM72592.1 - 0.02 15.2 0.1 0.068 13.5 0.1 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFM72593.1 - 1.3e-20 73.7 0.1 5e-11 43.0 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFM72593.1 - 2.3e-17 63.1 0.1 6.3e-10 39.3 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM72593.1 - 8.9e-14 51.4 0.5 2.7e-06 27.5 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM72593.1 - 5.4e-12 45.6 0.0 1.3e-09 38.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFM72593.1 - 2.7e-05 24.3 0.1 0.055 13.7 0.0 3.7 3 1 1 4 4 4 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM72593.1 - 9.6e-05 22.4 0.6 0.0065 16.5 0.0 3.2 3 2 0 3 3 3 1 CD80-like C2-set immunoglobulin domain DUF3146 PF11344.8 KFM72593.1 - 0.098 12.3 0.0 7.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) zf-BED PF02892.15 KFM72594.1 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_4 PF13894.6 KFM72594.1 - 0.1 13.5 0.2 0.32 12.0 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM72594.1 - 0.16 12.3 1.1 0.37 11.1 0.5 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HTH_Tnp_Tc3_2 PF01498.18 KFM72597.1 - 1.8e-16 60.1 2.2 4.2e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72597.1 - 8.4e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Reprolysin PF01421.19 KFM72598.1 - 1.1e-48 165.8 0.4 1.3e-48 165.5 0.4 1.1 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KFM72598.1 - 2.9e-14 53.7 0.8 3.7e-14 53.3 0.8 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFM72598.1 - 1.6e-12 48.0 0.1 2.2e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFM72598.1 - 1.5e-09 37.8 2.5 3e-09 36.8 2.5 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFM72598.1 - 2.8e-06 27.4 4.1 4.6e-06 26.7 4.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFM72598.1 - 1.1 9.1 2.9 2.6 7.9 3.0 1.6 1 1 0 1 1 1 0 Matrixin FAO_M PF16350.5 KFM72599.1 - 0.18 12.2 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase central domain HTH_Tnp_Tc3_2 PF01498.18 KFM72600.1 - 4.5e-16 58.8 3.5 5.7e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72600.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72600.1 - 2.8e-07 30.2 0.2 7e-07 28.9 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72600.1 - 0.0024 17.6 0.6 0.0075 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72600.1 - 1.8 9.2 15.6 0.12 13.0 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM72601.1 - 5.3e-05 23.0 0.0 6e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72602.1 - 5.3e-16 58.6 3.5 6.2e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72602.1 - 1.4e-13 50.9 0.0 2.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72602.1 - 3e-07 30.1 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72602.1 - 0.0029 17.4 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72602.1 - 0.031 14.4 0.4 0.097 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM72602.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HRM PF02793.22 KFM72604.1 - 5.3e-17 61.9 5.8 6e-17 61.7 5.8 1.1 1 0 0 1 1 1 1 Hormone receptor domain 7tm_2 PF00002.24 KFM72605.1 - 4.3e-28 98.3 2.9 4.5e-28 98.2 2.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) zf-H2C2_2 PF13465.6 KFM72606.1 - 4e-78 254.6 94.1 1.5e-08 34.7 0.6 13.4 13 1 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72606.1 - 9.5e-65 211.6 92.4 9.7e-06 25.8 2.4 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72606.1 - 5.4e-48 157.5 87.1 0.00066 20.3 0.4 12.1 11 1 1 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM72606.1 - 3e-36 122.8 84.1 0.00035 20.9 1.3 12.4 12 0 0 12 12 12 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM72606.1 - 3.3e-28 97.3 65.9 0.0066 16.7 0.1 12.2 12 0 0 12 12 12 10 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM72606.1 - 8.5e-21 73.4 58.2 0.0065 16.2 0.1 12.0 12 0 0 12 12 12 9 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM72606.1 - 6.3e-18 64.2 70.4 0.07 12.9 1.1 12.5 12 0 0 12 12 12 9 C2H2-type zinc-finger domain GAGA PF09237.11 KFM72606.1 - 3.7e-15 55.5 1.6 0.63 9.9 0.0 8.6 2 2 8 10 10 10 3 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM72606.1 - 1.6e-13 50.4 33.8 0.77 9.9 0.1 10.7 8 2 3 11 11 11 3 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 KFM72606.1 - 2.2e-13 49.8 80.7 0.01 15.8 1.4 12.4 11 1 1 12 12 12 9 C2H2-type zinc finger BolA PF01722.18 KFM72606.1 - 1.8e-11 44.1 20.7 0.065 13.5 0.2 8.5 1 1 7 8 8 8 3 BolA-like protein DUF4825 PF16107.5 KFM72606.1 - 2.3e-08 34.0 0.4 3.4 7.8 0.0 6.2 2 2 5 7 7 7 1 Domain of unknown function (DUF4825) zf-C2H2_9 PF16293.5 KFM72606.1 - 3.3e-08 33.3 50.2 0.45 10.4 0.2 11.7 4 3 8 12 12 12 2 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KFM72606.1 - 4.8e-08 32.5 55.1 0.38 10.4 0.3 10.8 4 4 7 11 11 11 6 MYST family zinc finger domain zf-C2HC_2 PF13913.6 KFM72606.1 - 1.3e-06 28.2 41.7 2.9 7.9 0.1 11.1 11 1 0 11 11 10 4 zinc-finger of a C2HC-type DUF952 PF06108.12 KFM72606.1 - 5.2e-06 26.4 0.7 5.5 7.1 0.1 5.7 2 2 4 7 7 7 0 Protein of unknown function (DUF952) zf-RRPl_C4 PF17026.5 KFM72606.1 - 5.5e-06 26.4 54.0 0.2 11.8 9.1 5.8 1 1 4 5 5 5 4 Putative ribonucleoprotein zinc-finger pf C4 type Zf_RING PF16744.5 KFM72606.1 - 1.2e-05 25.3 52.1 3.2 7.9 1.0 10.8 1 1 5 8 8 8 2 KIAA1045 RING finger EKR PF10371.9 KFM72606.1 - 2.3e-05 24.1 0.0 12 5.7 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function zinc_ribbon_15 PF17032.5 KFM72606.1 - 4.1e-05 24.3 50.2 1.3 9.9 1.6 6.3 1 1 3 6 6 6 5 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM72606.1 - 5.7e-05 23.4 90.6 4.3 7.7 2.8 11.4 1 1 11 12 12 12 3 C2H2 type zinc-finger (2 copies) Tox-HNH-HHH PF15637.6 KFM72606.1 - 0.00011 22.3 4.1 5.2 7.3 0.1 4.3 1 1 2 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-DBF PF07535.12 KFM72606.1 - 0.00013 22.0 51.2 5.9 7.1 0.5 11.0 11 0 0 11 11 11 0 DBF zinc finger DUF2256 PF10013.9 KFM72606.1 - 0.00024 21.2 40.5 18 5.6 0.2 11.4 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) Baculo_IE-1 PF05290.11 KFM72606.1 - 0.00029 20.8 42.1 0.59 10.1 2.1 8.1 1 1 5 6 6 6 3 Baculovirus immediate-early protein (IE-0) C1_1 PF00130.22 KFM72606.1 - 0.0068 16.3 63.2 1.5 8.8 5.1 10.1 3 3 7 10 10 10 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Imm25 PF15564.6 KFM72606.1 - 0.007 16.3 0.2 33 4.4 0.0 4.4 2 1 0 3 3 3 0 Immunity protein 25 zf-C2H2_8 PF15909.5 KFM72606.1 - 0.018 15.3 55.2 0.089 13.1 3.2 6.8 1 1 5 6 6 6 0 C2H2-type zinc ribbon Glyco_hydro_20 PF00728.22 KFM72606.1 - 0.26 10.7 9.1 3.2 7.0 2.3 3.4 1 1 2 3 3 3 0 Glycosyl hydrolase family 20, catalytic domain Complex1_49kDa PF00346.19 KFM72606.1 - 0.42 9.7 11.3 7.4 5.6 0.1 3.3 1 1 1 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf_UBZ PF18439.1 KFM72606.1 - 0.66 9.6 46.0 14 5.4 0.1 11.0 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger DUF2645 PF10840.8 KFM72606.1 - 1.7 9.3 7.3 20 5.9 0.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2645) Mga PF05043.13 KFM72606.1 - 5 7.8 8.8 78 4.0 0.2 4.4 4 0 0 4 4 4 0 Mga helix-turn-helix domain LIM PF00412.22 KFM72606.1 - 8.4 6.7 57.9 16 5.9 4.9 10.1 3 2 4 8 8 8 0 LIM domain zf-H2C2_2 PF13465.6 KFM72608.1 - 2.3e-67 220.6 76.2 8.5e-09 35.5 1.2 10.9 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72608.1 - 2.1e-45 150.7 82.7 2.6e-05 24.4 0.9 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72608.1 - 4.8e-36 120.3 77.4 0.00083 20.0 1.6 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM72608.1 - 9.2e-29 99.0 73.3 0.00038 20.8 0.9 10.2 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM72608.1 - 3.2e-16 59.1 53.9 0.057 13.7 0.5 10.3 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM72608.1 - 2.8e-12 46.5 32.4 0.18 11.9 0.9 9.8 9 1 1 10 10 10 5 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 KFM72608.1 - 2.6e-11 43.1 58.4 0.00038 20.1 0.3 9.6 10 0 0 10 10 10 6 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM72608.1 - 9.5e-11 41.3 63.5 0.05 13.4 0.4 10.7 11 0 0 11 11 11 7 C2H2-type zinc-finger domain GAGA PF09237.11 KFM72608.1 - 3.6e-06 26.7 9.8 1.8 8.4 0.0 6.3 3 2 4 7 7 7 2 GAGA factor BolA PF01722.18 KFM72608.1 - 1.5e-05 25.2 13.2 2.5 8.4 0.0 5.8 1 1 4 6 6 6 1 BolA-like protein zf-RRPl_C4 PF17026.5 KFM72608.1 - 1.6e-05 25.0 46.3 0.078 13.1 5.3 4.4 1 1 4 5 5 5 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_8 PF15909.5 KFM72608.1 - 2.4e-05 24.5 43.6 0.022 15.0 2.0 6.0 1 1 5 6 6 6 3 C2H2-type zinc ribbon Tox-HNH-HHH PF15637.6 KFM72608.1 - 2.6e-05 24.3 0.6 3.9 7.7 0.0 4.2 1 1 2 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_6 PF13912.6 KFM72608.1 - 6.1e-05 22.9 71.0 0.13 12.3 1.3 10.2 10 1 0 10 10 10 4 C2H2-type zinc finger zf-MYST PF17772.1 KFM72608.1 - 0.00057 19.4 54.0 0.0086 15.7 0.8 9.9 5 4 5 10 10 10 1 MYST family zinc finger domain zf-C2H2_9 PF16293.5 KFM72608.1 - 0.0008 19.2 43.4 1.7 8.5 0.2 9.5 3 2 7 10 10 10 3 C2H2 type zinc-finger (1 copy) C1_4 PF07975.12 KFM72608.1 - 0.0024 18.1 48.5 0.0039 17.4 4.1 6.9 3 2 5 8 8 8 2 TFIIH C1-like domain zf-DBF PF07535.12 KFM72608.1 - 0.0046 17.0 49.5 4.4 7.5 0.1 10.1 9 1 1 10 10 10 1 DBF zinc finger zinc_ribbon_15 PF17032.5 KFM72608.1 - 0.0088 16.8 46.4 0.067 13.9 1.3 5.9 1 1 3 5 5 5 2 zinc-ribbon family DUF1493 PF07377.12 KFM72608.1 - 0.15 12.5 0.2 14 6.1 0.0 3.2 1 1 1 4 4 4 0 Protein of unknown function (DUF1493) Mga PF05043.13 KFM72608.1 - 0.17 12.5 2.9 2.6 8.7 0.1 3.4 3 1 1 4 4 4 0 Mga helix-turn-helix domain zf-C2HC_2 PF13913.6 KFM72608.1 - 0.39 10.7 39.6 9.6 6.2 0.5 9.1 9 0 0 9 9 9 0 zinc-finger of a C2HC-type Complex1_49kDa PF00346.19 KFM72608.1 - 0.48 9.5 5.0 1.3 8.0 0.7 2.6 1 1 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Z1 PF10593.9 KFM72608.1 - 0.86 9.1 9.9 6.2 6.2 0.6 3.4 1 1 2 3 3 3 0 Z1 domain zf-Dof PF02701.15 KFM72608.1 - 1.2 9.3 40.5 2.4 8.4 0.1 8.2 1 1 6 7 7 7 0 Dof domain, zinc finger zf-C2H2_2 PF12756.7 KFM72608.1 - 2.6 8.4 72.3 2.5 8.5 1.3 9.6 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 KFM72608.1 - 4.1 7.6 48.6 23 5.2 0.1 9.4 1 1 8 9 9 9 0 KIAA1045 RING finger RVT_1 PF00078.27 KFM72609.1 - 4.9e-09 36.0 0.0 5.6e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Corona_NS4 PF03905.13 KFM72609.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Coronavirus non-structural protein NS4 HTH_Tnp_Tc3_2 PF01498.18 KFM72611.1 - 2.2e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72611.1 - 8.9e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ig_3 PF13927.6 KFM72613.1 - 1.8e-39 134.2 0.0 1e-11 45.3 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 KFM72613.1 - 9.4e-36 121.8 0.0 3.3e-11 43.1 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM72613.1 - 9.6e-31 106.0 0.1 2.4e-09 37.4 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFM72613.1 - 1.2e-15 57.4 0.2 0.00046 20.3 0.0 5.2 4 2 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFM72613.1 - 1.5e-08 34.8 6.5 0.084 13.1 0.4 6.9 5 3 0 5 5 5 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM72613.1 - 6.4e-08 32.0 0.0 0.051 13.2 0.0 3.6 4 0 0 4 4 4 3 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM72613.1 - 0.0028 17.7 0.2 1.3 9.1 0.0 3.9 4 2 0 4 4 4 1 C17orf99 Ig domain C2-set_2 PF08205.12 KFM72613.1 - 0.015 15.3 0.3 12 6.0 0.0 3.3 4 0 0 4 4 4 0 CD80-like C2-set immunoglobulin domain Lep_receptor_Ig PF06328.11 KFM72613.1 - 0.15 12.1 0.1 1.8 8.6 0.0 2.6 3 0 0 3 3 3 0 Ig-like C2-type domain Ras PF00071.22 KFM72615.1 - 3.2e-06 26.8 0.0 3.3e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Aldedh PF00171.22 KFM72617.1 - 2.8e-85 286.6 0.0 3.5e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Myb_DNA-bind_6 PF13921.6 KFM72619.1 - 3.8e-37 126.3 9.3 2.3e-19 69.4 0.9 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFM72619.1 - 1.7e-36 124.2 17.4 1.6e-17 63.4 1.6 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFM72619.1 - 7.1e-06 25.8 2.3 0.0013 18.6 0.1 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KFM72619.1 - 3.5e-05 23.9 4.9 0.18 12.0 0.2 3.0 1 1 2 3 3 3 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 KFM72619.1 - 0.00033 20.7 0.3 0.0089 16.0 0.1 2.7 1 1 1 2 2 2 1 SLIDE WIYLD PF10440.9 KFM72619.1 - 0.011 15.5 0.4 0.79 9.6 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF4085 PF13315.6 KFM72619.1 - 0.032 13.9 0.1 1.9 8.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) Rap1_C PF11626.8 KFM72619.1 - 0.068 13.3 5.7 1.4 9.1 0.4 2.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KFM72619.1 - 0.94 9.9 11.9 3.2 8.2 1.4 3.3 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Cmyb_C PF09316.10 KFM72620.1 - 2.4e-06 27.3 0.0 5.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 C-myb, C-terminal Folate_rec PF03024.14 KFM72620.1 - 0.0034 17.3 0.5 0.0034 17.3 0.5 2.0 2 0 0 2 2 2 1 Folate receptor family DUF4539 PF15072.6 KFM72621.1 - 1.8e-13 50.3 0.4 4.2e-13 49.2 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Importin_rep_3 PF18806.1 KFM72622.1 - 5e-31 106.6 0.1 4e-30 103.7 0.0 2.6 3 0 0 3 3 3 1 Importin 13 repeat ORC5_C PF14630.6 KFM72622.1 - 0.0017 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus PCP PF02429.15 KFM72622.1 - 0.028 14.8 0.3 0.68 10.3 0.0 2.9 3 0 0 3 3 3 0 Peridinin-chlorophyll A binding protein DUF3938 PF13074.6 KFM72622.1 - 0.039 14.2 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Xpo1 PF08389.12 KFM72623.1 - 3.7e-16 59.5 3.1 8.8e-16 58.3 3.1 1.7 1 0 0 1 1 1 1 Exportin 1-like protein Importin_rep PF18773.1 KFM72623.1 - 7.4e-13 48.0 4.2 2e-12 46.6 4.2 1.8 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 KFM72623.1 - 2.5e-08 33.7 0.5 1.2e-07 31.5 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF2181 PF10223.9 KFM72624.1 - 9.6e-69 231.5 0.0 1.1e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) PDZ PF00595.24 KFM72625.1 - 4.3e-65 216.0 11.4 7.3e-18 64.7 0.7 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFM72625.1 - 1.5e-37 127.2 3.2 2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFM72625.1 - 7.3e-24 83.9 3.1 0.00012 22.3 0.1 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_4 PF17816.1 KFM72625.1 - 0.00061 20.2 0.3 18 5.8 0.0 4.5 4 1 0 4 4 4 1 PDZ domain GRASP55_65 PF04495.14 KFM72625.1 - 0.0023 18.3 0.0 0.013 15.8 0.0 2.0 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain zf-H2C2_2 PF13465.6 KFM72626.1 - 4.4e-107 346.2 85.1 3.7e-08 33.4 0.6 15.1 15 0 0 15 15 15 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72626.1 - 4.2e-61 200.1 122.7 4.2e-05 23.7 1.2 15.2 15 0 0 15 15 15 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72626.1 - 2.4e-50 164.8 114.6 0.00092 19.9 0.9 15.1 15 0 0 15 15 15 14 C2H2-type zinc finger zf-met PF12874.7 KFM72626.1 - 1.1e-23 82.8 106.8 0.012 16.0 0.6 15.3 15 0 0 15 15 15 12 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM72626.1 - 6.7e-21 73.7 82.4 0.028 14.2 0.1 15.1 15 0 0 15 15 15 11 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM72626.1 - 8.8e-14 51.4 79.9 0.0012 19.1 2.6 14.2 14 1 1 15 15 14 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM72626.1 - 4.7e-13 48.8 87.0 0.26 11.3 0.1 14.9 15 0 0 15 15 14 10 C2H2-type zinc finger BolA PF01722.18 KFM72626.1 - 1.2e-09 38.3 21.0 0.52 10.6 0.1 8.3 2 2 6 8 8 8 3 BolA-like protein ADK_lid PF05191.14 KFM72626.1 - 1.5e-08 34.5 35.6 0.55 10.3 2.8 9.3 3 3 5 8 8 8 3 Adenylate kinase, active site lid GAGA PF09237.11 KFM72626.1 - 3.6e-06 26.7 33.0 0.78 9.6 0.1 9.6 2 2 7 10 10 10 4 GAGA factor zf-C2HC_2 PF13913.6 KFM72626.1 - 4.2e-06 26.5 62.6 0.74 9.8 0.2 13.7 14 0 0 14 14 14 4 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM72626.1 - 1.2e-05 25.3 56.6 4.5 7.5 0.2 13.7 14 0 0 14 14 14 2 DBF zinc finger zinc_ribbon_15 PF17032.5 KFM72626.1 - 0.0012 19.5 53.2 0.73 10.6 0.3 7.4 5 2 3 8 8 8 3 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM72626.1 - 0.0017 18.4 54.5 0.2 11.7 6.5 6.2 1 1 7 8 8 8 3 Putative ribonucleoprotein zinc-finger pf C4 type Tox-HNH-HHH PF15637.6 KFM72626.1 - 0.0049 17.0 8.3 4.4 7.5 0.3 5.1 3 2 1 5 5 5 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Sec23_Sec24 PF04810.15 KFM72626.1 - 0.034 14.2 54.5 4.4 7.4 0.1 13.4 12 1 2 14 14 14 0 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM72626.1 - 0.049 13.3 59.1 0.88 9.2 0.1 13.1 7 4 7 14 14 14 0 MYST family zinc finger domain Plus-3 PF03126.18 KFM72626.1 - 0.067 13.7 1.5 22 5.6 0.1 3.8 3 1 1 4 4 3 0 Plus-3 domain FYVE PF01363.21 KFM72626.1 - 0.53 10.5 74.4 0.99 9.6 10.7 7.2 2 2 5 7 7 7 0 FYVE zinc finger PqqA PF08042.11 KFM72626.1 - 1.4 9.1 7.8 5.9e+02 0.7 0.0 7.2 10 0 0 10 10 10 0 PqqA family zf-C2H2_9 PF16293.5 KFM72626.1 - 2 8.3 56.8 4 7.3 1.0 12.6 5 4 10 15 15 15 0 C2H2 type zinc-finger (1 copy) DUF4990 PF16380.5 KFM72626.1 - 7.5 6.7 11.9 86 3.2 0.0 6.8 10 0 0 10 10 9 0 Domain of unknown function MULE PF10551.9 KFM72627.1 - 0.00019 21.8 0.1 0.00025 21.4 0.1 1.1 1 0 0 1 1 1 1 MULE transposase domain zf-H2C2_2 PF13465.6 KFM72628.1 - 5.6e-97 314.2 91.3 5.1e-09 36.2 0.8 14.1 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72628.1 - 5.4e-71 231.3 105.8 2e-06 27.9 1.2 13.6 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72628.1 - 1.6e-51 168.5 99.3 0.00035 21.2 0.7 13.2 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM72628.1 - 4.3e-41 138.1 102.0 0.00018 21.8 1.6 13.4 13 0 0 13 13 13 13 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM72628.1 - 8.1e-24 83.4 69.7 0.0011 19.2 0.1 13.4 13 0 0 13 13 13 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM72628.1 - 1.6e-16 59.9 99.0 0.00033 20.6 1.1 14.3 13 1 0 13 13 13 9 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM72628.1 - 1.1e-14 53.9 71.7 0.035 13.9 0.1 14.1 14 0 0 14 14 14 8 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM72628.1 - 1.8e-11 43.6 47.1 0.23 11.4 0.3 12.9 13 0 0 13 13 13 3 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM72628.1 - 6.4e-10 38.8 41.0 0.022 14.7 0.2 8.7 3 3 9 12 12 12 7 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM72628.1 - 8.1e-10 38.8 5.1 0.12 12.5 0.1 5.8 2 2 4 6 6 6 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-DBF PF07535.12 KFM72628.1 - 2.1e-07 30.9 57.7 5.4 7.2 0.1 13.2 13 0 0 13 13 13 1 DBF zinc finger BolA PF01722.18 KFM72628.1 - 1.9e-06 28.1 20.5 0.1 12.9 0.3 7.6 2 2 5 7 7 7 1 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM72628.1 - 3.7e-05 23.7 49.1 9 6.4 0.2 12.5 10 3 3 13 13 13 0 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM72628.1 - 5.3e-05 23.3 50.1 0.83 9.8 0.9 6.3 1 1 5 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type zf-CHCC PF10276.9 KFM72628.1 - 0.0081 16.2 18.3 1e+02 3.1 0.0 9.9 12 0 0 12 12 11 0 Zinc-finger domain DUF2256 PF10013.9 KFM72628.1 - 0.027 14.6 43.9 23 5.2 0.0 12.5 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_1 PF00130.22 KFM72628.1 - 0.074 13.0 70.2 13 5.7 0.1 11.9 1 1 10 11 11 11 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Complex1_49kDa PF00346.19 KFM72628.1 - 0.13 11.3 0.3 3.8 6.5 0.0 2.8 2 1 1 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit XPA_N PF01286.18 KFM72628.1 - 0.15 12.1 49.7 10 6.2 0.3 12.4 13 0 0 13 13 13 0 XPA protein N-terminal GAGA PF09237.11 KFM72628.1 - 0.18 11.6 28.3 6.8 6.6 0.0 8.9 2 2 7 10 10 10 0 GAGA factor zf-C2H2_2 PF12756.7 KFM72628.1 - 0.27 11.6 83.1 1.7 9.0 1.7 12.3 1 1 11 12 12 12 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM72628.1 - 0.33 10.6 50.4 11 5.7 0.2 11.9 9 3 4 13 13 13 0 MYST family zinc finger domain zf-C2H2_9 PF16293.5 KFM72628.1 - 0.33 10.8 55.9 28 4.6 0.7 12.6 2 1 11 13 13 13 0 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 KFM72628.1 - 0.35 10.5 60.1 2.1 8.0 0.2 12.9 13 0 0 13 13 13 0 Ubiquitin-Binding Zinc Finger PqqA PF08042.11 KFM72628.1 - 0.44 10.6 8.3 5.1e+02 0.9 0.0 7.5 10 0 0 10 10 10 0 PqqA family FYVE PF01363.21 KFM72628.1 - 0.54 10.4 66.2 0.11 12.6 7.5 7.2 1 1 4 5 5 4 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM72628.1 - 0.63 10.8 54.4 0.36 11.6 2.0 7.0 1 1 7 8 8 7 0 zinc-ribbon family zf-Dof PF02701.15 KFM72628.1 - 1.2 9.4 34.4 0.27 11.4 0.7 8.8 2 2 8 10 10 10 0 Dof domain, zinc finger TRAF6_Z2 PF18048.1 KFM72628.1 - 2.6 8.2 64.6 0.42 10.8 0.5 12.7 14 0 0 14 14 13 0 TNF receptor-associated factor 6 zinc finger 2 Flag1_repress PF03614.13 KFM72628.1 - 2.7 7.8 5.6 25 4.6 0.0 3.6 1 1 3 5 5 5 0 Repressor of phase-1 flagellin Scramblase PF03803.15 KFM72628.1 - 3.8 6.7 9.9 1.3 8.3 0.2 3.4 2 1 2 4 4 4 0 Scramblase Zn-ribbon_8 PF09723.10 KFM72628.1 - 6 7.1 48.5 3 8.1 2.9 8.3 3 3 8 11 11 11 0 Zinc ribbon domain JAB PF01398.21 KFM72629.1 - 1.6e-32 112.0 0.0 3e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFM72629.1 - 1.6e-14 54.3 1.0 2.7e-14 53.5 1.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KFM72629.1 - 2.4e-06 27.3 0.0 4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HTH_38 PF13936.6 KFM72630.1 - 4.4e-07 29.6 0.0 8.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72630.1 - 0.00018 21.2 0.1 0.00042 20.0 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Bac_DnaA_C PF08299.11 KFM72630.1 - 0.0086 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix Sigma70_r4 PF04545.16 KFM72630.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_50 PF18024.1 KFM72630.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KFM72630.1 - 0.15 11.7 0.0 0.54 10.0 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 KFM72630.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding WD40 PF00400.32 KFM72632.1 - 0.00054 20.7 0.0 1.2 10.1 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat VID27 PF08553.10 KFM72632.1 - 0.033 13.2 0.0 0.087 11.9 0.0 1.5 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 KFM72632.1 - 0.061 12.3 0.0 1.6 7.6 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CNH PF00780.22 KFM72632.1 - 0.063 12.9 0.2 1.3 8.6 0.1 2.8 2 1 0 2 2 2 0 CNH domain NPL4 PF05021.15 KFM72634.1 - 2e-115 385.4 0.0 2.5e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KFM72634.1 - 8.2e-60 201.2 1.1 8.2e-60 201.2 1.1 2.1 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KFM72634.1 - 8.6e-15 55.0 0.0 2.4e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.18 KFM72634.1 - 0.0026 17.0 1.8 0.0026 17.0 1.8 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DDE_Tnp_4 PF13359.6 KFM72635.1 - 4.5e-39 133.7 0.0 5.1e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 KFM72635.1 - 0.15 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Neur_chan_memb PF02932.16 KFM72637.1 - 2.8e-29 102.9 3.8 9.7e-25 88.0 0.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM72637.1 - 4.5e-08 32.8 0.3 6.7e-08 32.2 0.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain WD40 PF00400.32 KFM72641.1 - 1.4e-11 44.7 3.7 0.00051 20.8 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_like PF17005.5 KFM72641.1 - 0.0003 20.2 0.0 0.051 12.9 0.0 1.7 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 KFM72641.1 - 0.00078 19.7 0.0 6.6 7.1 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM72641.1 - 0.039 12.9 0.7 11 4.8 0.0 3.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NHL PF01436.21 KFM72642.1 - 0.0061 16.6 0.7 0.011 15.7 0.7 1.4 1 0 0 1 1 1 1 NHL repeat Pkinase PF00069.25 KFM72644.1 - 3.7e-39 134.7 0.0 4.5e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM72644.1 - 6.9e-19 68.1 0.0 7.9e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM72644.1 - 1.2e-07 31.4 0.0 2.1e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Sec63 PF02889.16 KFM72645.1 - 9.7e-21 74.1 6.2 1.8e-10 40.4 0.5 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 KFM72645.1 - 2.2e-18 66.1 0.2 2.2e-18 66.1 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain FliG_N PF14842.6 KFM72645.1 - 0.088 13.4 0.1 0.27 11.8 0.1 1.9 1 1 0 1 1 1 0 FliG N-terminal domain PHC2_SAM_assoc PF16616.5 KFM72645.1 - 1.6 9.5 10.3 3.7 8.4 10.3 1.6 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Fibrinogen_C PF00147.18 KFM72646.1 - 4e-61 206.6 11.3 5.6e-61 206.1 11.3 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain COLFI PF01410.18 KFM72646.1 - 0.041 13.2 1.1 0.07 12.4 1.1 1.4 1 1 0 1 1 1 0 Fibrillar collagen C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM72647.1 - 5.1e-16 58.7 3.5 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72647.1 - 3.3e-13 49.6 0.0 5.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72647.1 - 2.9e-07 30.1 0.2 6.9e-07 28.9 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72647.1 - 0.0025 17.5 0.6 0.0074 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72647.1 - 0.03 14.5 0.4 0.089 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM72647.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM72648.1 - 4.7e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72648.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72648.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72648.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72648.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain AMP-binding PF00501.28 KFM72649.1 - 5e-17 61.6 0.1 5.4e-17 61.5 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DDE_3 PF13358.6 KFM72652.1 - 1.2e-16 60.8 0.1 1.4e-15 57.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72652.1 - 6.9e-16 58.3 6.5 1.4e-15 57.3 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72652.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72652.1 - 0.0024 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72652.1 - 0.014 15.5 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM72652.1 - 0.033 14.2 2.6 0.034 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix zf-H2C2_2 PF13465.6 KFM72653.1 - 4.7e-91 295.5 120.7 1.5e-09 37.8 0.8 17.4 17 1 0 17 17 17 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72653.1 - 6.5e-68 221.6 150.4 1.9e-05 24.8 0.4 16.2 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72653.1 - 1.5e-47 156.1 138.0 0.00027 21.5 1.8 16.2 16 0 0 16 16 16 16 C2H2-type zinc finger zf-met PF12874.7 KFM72653.1 - 2.8e-29 100.6 112.3 0.0002 21.7 1.2 16.3 16 0 0 16 16 16 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM72653.1 - 4.3e-23 80.8 115.5 0.0017 18.3 1.1 16.1 16 0 0 16 16 16 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM72653.1 - 1.1e-14 54.3 91.9 0.0028 17.9 0.7 15.5 15 1 1 16 16 16 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM72653.1 - 2.8e-08 33.4 105.4 0.01 15.5 0.3 16.6 16 0 0 16 16 16 7 C2H2-type zinc-finger domain zf-RRPl_C4 PF17026.5 KFM72653.1 - 9.1e-06 25.7 66.0 0.051 13.7 7.7 7.4 1 1 7 8 8 8 6 Putative ribonucleoprotein zinc-finger pf C4 type BolA PF01722.18 KFM72653.1 - 9.9e-06 25.8 23.5 6.9 7.0 0.3 8.4 2 2 5 8 8 8 1 BolA-like protein Complex1_49kDa PF00346.19 KFM72653.1 - 0.00026 20.2 0.4 0.3 10.2 0.2 3.0 2 1 0 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zinc_ribbon_15 PF17032.5 KFM72653.1 - 0.0006 20.5 58.9 1.2 9.9 0.2 8.4 2 1 6 8 8 8 4 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM72653.1 - 0.0059 16.4 68.7 2.4 8.1 0.3 15.0 7 5 9 16 16 16 2 C2H2 type zinc-finger (1 copy) TRAF6_Z2 PF18048.1 KFM72653.1 - 0.13 12.4 0.2 0.13 12.4 0.2 13.6 15 0 0 15 15 15 0 TNF receptor-associated factor 6 zinc finger 2 NusB PF01029.18 KFM72653.1 - 0.16 12.2 0.8 8.9 6.5 0.0 3.7 5 0 0 5 5 4 0 NusB family GAGA PF09237.11 KFM72653.1 - 0.3 10.9 39.6 3.9 7.4 0.2 10.7 4 3 10 14 14 14 0 GAGA factor DUF2256 PF10013.9 KFM72653.1 - 1.5 9.0 62.2 18 5.6 0.1 14.5 16 0 0 16 16 16 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM72653.1 - 2.7 8.0 55.5 0.25 11.3 1.9 9.7 7 4 2 9 9 9 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM72653.1 - 7 7.0 113.4 0.48 10.8 1.1 14.7 1 1 12 13 13 12 0 C2H2 type zinc-finger (2 copies) RVT_2 PF07727.14 KFM72654.1 - 8.5e-65 218.8 0.1 1.6e-64 217.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 KFM72656.1 - 1.6e-149 480.4 173.6 3.3e-09 36.7 0.3 25.9 26 0 0 26 26 26 23 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72656.1 - 8e-106 341.0 207.0 1.4e-05 25.3 0.7 24.9 25 0 0 25 25 25 23 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72656.1 - 2.5e-66 214.5 196.8 0.00098 19.8 1.4 24.9 25 0 0 25 25 25 23 C2H2-type zinc finger zf-met PF12874.7 KFM72656.1 - 1.2e-61 203.5 179.0 1.7e-05 25.0 2.4 23.5 23 0 0 23 23 23 21 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM72656.1 - 5.5e-40 134.7 156.5 0.0021 18.0 0.7 23.7 23 0 0 23 23 23 17 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM72656.1 - 1.4e-25 88.9 130.9 0.0081 16.4 0.3 22.3 22 0 0 22 22 22 13 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM72656.1 - 7.2e-08 32.6 34.1 7.7 6.9 0.1 12.3 3 3 7 11 11 11 2 BolA-like protein ADK_lid PF05191.14 KFM72656.1 - 1.1e-06 28.5 90.0 0.0028 17.6 0.4 13.3 7 2 7 14 14 14 5 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM72656.1 - 6.5e-06 25.7 107.2 0.24 11.0 0.7 20.0 9 5 13 22 22 22 9 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFM72656.1 - 0.00021 22.0 87.8 1.9 9.3 1.2 11.3 3 2 9 13 13 13 7 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM72656.1 - 0.00053 20.1 95.1 0.86 9.7 6.5 9.6 2 2 8 10 10 10 6 Putative ribonucleoprotein zinc-finger pf C4 type GAGA PF09237.11 KFM72656.1 - 0.00066 19.4 49.2 1.6 8.6 0.5 13.9 5 4 13 18 18 18 3 GAGA factor Complex1_49kDa PF00346.19 KFM72656.1 - 0.036 13.2 4.3 1.5 7.9 0.1 4.1 3 3 2 5 5 5 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit SspN PF08177.11 KFM72656.1 - 0.041 13.8 1.1 0.45 10.5 1.1 3.0 1 0 0 1 1 1 0 Small acid-soluble spore protein N family zf-C2H2_11 PF16622.5 KFM72656.1 - 0.069 12.9 0.3 0.069 12.9 0.3 20.9 22 0 0 22 22 22 0 zinc-finger C2H2-type TRAF6_Z2 PF18048.1 KFM72656.1 - 0.35 11.0 0.1 0.35 11.0 0.1 17.1 18 1 1 19 19 19 0 TNF receptor-associated factor 6 zinc finger 2 zf-Sec23_Sec24 PF04810.15 KFM72656.1 - 3.3 7.8 83.5 2.4 8.3 1.0 18.7 17 3 5 22 22 22 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.6 KFM72658.1 - 3.6e-34 115.7 28.8 6.9e-07 29.4 0.2 6.1 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72658.1 - 5.4e-27 92.7 40.6 5.7e-06 26.5 1.9 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72658.1 - 7.6e-21 73.0 38.1 0.00036 21.1 1.5 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM72658.1 - 2.6e-16 59.4 37.6 0.0058 17.0 1.4 5.9 4 1 2 6 6 6 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM72658.1 - 2.4e-12 46.3 19.6 9e-05 22.1 0.7 5.8 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM72658.1 - 1.9e-10 40.8 34.9 0.00026 21.2 1.0 6.0 6 1 0 6 6 5 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM72658.1 - 7.1e-08 32.3 39.9 0.094 12.7 1.1 5.9 5 2 0 5 5 5 5 C2H2-type zinc finger zf_UBZ PF18439.1 KFM72658.1 - 0.00022 20.7 24.3 0.38 10.4 0.3 5.3 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KFM72658.1 - 0.00066 19.5 16.0 1.4 8.8 0.5 5.0 2 2 3 5 5 5 2 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 KFM72658.1 - 0.00069 19.5 14.5 0.14 12.2 1.5 3.6 3 0 0 3 3 3 2 Adenylate kinase, active site lid BolA PF01722.18 KFM72658.1 - 0.00086 19.5 4.5 0.014 15.7 0.6 3.1 1 1 1 3 3 3 1 BolA-like protein TRAF6_Z2 PF18048.1 KFM72658.1 - 0.0013 18.8 25.3 2 8.6 0.3 5.5 5 0 0 5 5 5 2 TNF receptor-associated factor 6 zinc finger 2 zf-MYST PF17772.1 KFM72658.1 - 0.0049 16.4 21.2 0.28 10.8 1.6 5.0 4 1 1 5 5 5 1 MYST family zinc finger domain DUF2256 PF10013.9 KFM72658.1 - 0.0059 16.7 13.6 5.9 7.1 0.2 5.1 5 0 0 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2256) Sprouty PF05210.13 KFM72658.1 - 0.032 14.6 5.1 0.032 14.6 5.1 2.7 1 1 1 3 3 3 0 Sprouty protein (Spry) zf-C2H2_2 PF12756.7 KFM72658.1 - 0.032 14.5 33.6 1.4 9.3 1.0 5.1 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) C5HCH PF17982.1 KFM72658.1 - 0.042 14.0 21.7 0.17 12.0 1.3 5.1 4 1 1 5 5 5 0 NSD Cys-His rich domain zf-RRPl_C4 PF17026.5 KFM72658.1 - 0.046 13.8 20.4 0.87 9.7 5.9 3.4 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFM72658.1 - 0.053 14.3 17.0 0.82 10.5 3.2 3.1 1 1 3 4 4 4 0 zinc-ribbon family HNH_5 PF14279.6 KFM72658.1 - 0.095 12.6 19.9 4.1 7.3 0.2 5.1 4 1 0 4 4 4 0 HNH endonuclease DUF2757 PF10955.8 KFM72658.1 - 0.13 12.5 18.3 3 8.2 0.2 4.9 2 2 3 5 5 5 0 Protein of unknown function (DUF2757) C1_1 PF00130.22 KFM72658.1 - 0.14 12.0 25.0 5.4 7.0 0.3 4.7 1 1 3 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 KFM72658.1 - 0.6 10.1 17.3 3.2 7.7 0.5 5.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type XPA_N PF01286.18 KFM72658.1 - 2.2 8.4 18.9 7.7 6.7 0.4 5.2 5 0 0 5 5 5 0 XPA protein N-terminal GAGA PF09237.11 KFM72658.1 - 2.6 7.9 12.9 2.6 7.9 0.1 4.1 3 2 2 5 5 5 0 GAGA factor Zn-ribbon_8 PF09723.10 KFM72658.1 - 3 8.0 16.9 19 5.5 1.7 3.9 2 1 1 3 3 3 0 Zinc ribbon domain zf-HIT PF04438.16 KFM72658.1 - 6 6.8 24.7 10 6.1 0.3 5.2 5 0 0 5 5 5 0 HIT zinc finger zf-DBF PF07535.12 KFM72658.1 - 6.9 6.9 24.7 6.4 7.0 0.1 5.4 5 1 0 5 5 5 0 DBF zinc finger zf-C2H2_11 PF16622.5 KFM72658.1 - 7.9 6.3 25.0 0.3 10.9 0.5 4.6 5 0 0 5 5 5 0 zinc-finger C2H2-type hSac2 PF12456.8 KFM72659.1 - 1.2e-18 66.9 0.0 3.4e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 Inositol phosphatase PMP22_Claudin PF00822.20 KFM72660.1 - 4.4e-14 52.7 3.7 6.3e-14 52.2 3.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFM72660.1 - 8.5e-05 22.4 10.8 8.5e-05 22.4 10.8 2.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 KFM72660.1 - 0.001 19.3 8.7 0.0024 18.1 8.7 1.6 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein BacA PF02673.18 KFM72660.1 - 0.0049 16.6 0.9 0.04 13.6 0.0 2.0 2 0 0 2 2 2 1 Bacitracin resistance protein BacA DUF1218 PF06749.12 KFM72660.1 - 0.0077 16.7 6.5 0.12 12.9 3.0 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1218) ECSCR PF15820.5 KFM72660.1 - 0.021 14.6 3.1 0.087 12.7 1.7 2.2 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator SUR7 PF06687.12 KFM72660.1 - 0.19 11.3 11.0 0.064 12.9 3.4 2.2 2 0 0 2 2 2 0 SUR7/PalI family Fumarate_red_D PF02313.17 KFM72660.1 - 0.81 9.8 7.3 1.4 9.0 3.3 2.4 2 1 0 2 2 2 0 Fumarate reductase subunit D Amastin PF07344.11 KFM72660.1 - 3.2 7.6 13.5 0.2 11.5 5.2 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein NB PF04159.13 KFM72660.1 - 3.3 7.8 6.2 2.7 8.1 1.7 2.5 3 0 0 3 3 3 0 NB glycoprotein Pkinase_Tyr PF07714.17 KFM72661.1 - 4.6e-86 288.3 0.2 1e-85 287.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFM72661.1 - 5.3e-46 157.1 0.0 1.3e-45 155.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain PBD PF00786.28 KFM72661.1 - 1.6e-06 28.4 0.1 7.1e-06 26.3 0.1 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain SH3_2 PF07653.17 KFM72661.1 - 0.0022 17.6 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain HBS1_N PF08938.10 KFM72661.1 - 0.0049 17.1 1.7 0.6 10.4 0.0 3.4 3 1 1 4 4 4 1 HBS1 N-terminus Haspin_kinase PF12330.8 KFM72661.1 - 0.015 14.3 0.2 0.045 12.7 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain SH3_9 PF14604.6 KFM72661.1 - 0.016 15.0 0.0 0.057 13.3 0.0 1.9 1 0 0 1 1 1 0 Variant SH3 domain Kinase-like PF14531.6 KFM72661.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4476 PF14771.6 KFM72661.1 - 0.11 12.9 0.1 1.5 9.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) DuoxA PF10204.9 KFM72662.1 - 2.2e-39 135.2 10.3 2.4e-39 135.0 10.3 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Herpes_UL73 PF03554.13 KFM72662.1 - 0.53 10.3 4.4 0.58 10.2 0.5 2.3 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein Mito_carr PF00153.27 KFM72665.1 - 4.2e-70 231.7 2.3 7e-25 86.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Patatin PF01734.22 KFM72666.1 - 4.4e-16 59.7 2.1 1.3e-15 58.1 0.5 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase DEAD PF00270.29 KFM72667.1 - 9.8e-32 110.1 0.1 1.6e-31 109.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM72667.1 - 2.1e-25 89.2 0.1 6.1e-25 87.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM72667.1 - 8.5e-07 29.1 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFM72667.1 - 9.6e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KFM72667.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Peptidase_C78 PF07910.13 KFM72667.1 - 0.087 12.3 0.0 0.31 10.5 0.0 1.8 2 1 0 2 2 2 0 Peptidase family C78 EGF_2 PF07974.13 KFM72669.1 - 0.00045 20.5 12.4 0.00045 20.5 12.4 2.1 2 0 0 2 2 2 1 EGF-like domain Coilin_N PF15862.5 KFM72669.1 - 0.00066 19.5 10.8 0.0012 18.6 10.8 1.6 1 0 0 1 1 1 1 Coilin N-terminus Paf1 PF03985.13 KFM72669.1 - 0.2 10.6 27.5 0.25 10.3 27.5 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 KFM72669.1 - 0.28 11.0 25.0 0.38 10.5 25.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RPN2_C PF18004.1 KFM72669.1 - 0.31 11.0 30.9 0.49 10.3 30.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SAPS PF04499.15 KFM72669.1 - 4.1 6.1 13.5 5.2 5.7 13.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_11 PF13086.6 KFM72669.1 - 7.5 6.3 15.4 9.8 5.9 15.4 1.1 1 0 0 1 1 1 0 AAA domain CLCA PF08434.11 KFM72670.1 - 1.7e-34 119.3 3.0 4.7e-34 117.9 3.0 1.6 1 1 0 1 1 1 1 Calcium-activated chloride channel N terminal tRNA_m1G_MT PF01746.21 KFM72672.1 - 8.1e-25 87.7 0.0 2.1e-24 86.3 0.0 1.7 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF3128 PF11326.8 KFM72672.1 - 0.051 14.0 0.1 0.051 14.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) Chitin_bind_4 PF00379.23 KFM72673.1 - 2e-10 41.0 2.1 4.7e-10 39.8 2.1 1.7 1 0 0 1 1 1 1 Insect cuticle protein Transposase_1 PF01359.18 KFM72676.1 - 5.2e-23 80.7 0.4 1.1e-22 79.7 0.4 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) DUF4795 PF16043.5 KFM72677.1 - 0.0086 15.7 4.4 0.0099 15.5 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 KFM72677.1 - 0.06 13.4 2.5 0.097 12.7 2.5 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Integrin_alpha PF00357.20 KFM72678.1 - 0.055 13.5 2.5 0.66 10.1 3.0 2.6 2 0 0 2 2 2 0 Integrin alpha cytoplasmic region Cpn60_TCP1 PF00118.24 KFM72679.1 - 9.9e-153 509.3 6.0 1.1e-152 509.1 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-UBP PF02148.19 KFM72681.1 - 5.5e-15 55.4 11.3 1.3e-14 54.3 11.3 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF4191 PF13829.6 KFM72684.1 - 0.12 11.6 1.0 0.16 11.3 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) TEX13 PF15186.6 KFM72684.1 - 0.21 11.3 12.4 0.024 14.3 5.1 2.1 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family HAUS6_N PF14661.6 KFM72684.1 - 0.21 11.1 9.5 0.24 10.9 9.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Cep57_CLD_2 PF14197.6 KFM72684.1 - 0.35 11.0 11.6 0.058 13.5 4.2 3.0 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 YabA PF06156.13 KFM72684.1 - 1.6 9.4 10.7 57 4.4 10.7 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Atg14 PF10186.9 KFM72684.1 - 2.1 7.3 12.4 2.3 7.2 12.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MCM_lid PF17855.1 KFM72686.1 - 2.2e-15 56.8 0.7 4e-15 56.0 0.7 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KFM72687.1 - 0.00017 21.4 4.6 0.00024 21.0 4.6 1.1 1 0 0 1 1 1 1 MCM OB domain DDE_3 PF13358.6 KFM72689.1 - 2.5e-09 37.1 0.0 4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72689.1 - 6.2e-07 29.6 0.1 1.3e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_3 PF01381.22 KFM72689.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix EIF_2_alpha PF07541.12 KFM72690.1 - 2.2e-35 121.2 0.2 6.6e-35 119.7 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KFM72690.1 - 3.3e-16 59.4 0.9 5.9e-16 58.6 0.9 1.4 1 0 0 1 1 1 1 S1 RNA binding domain DUF4453 PF14627.6 KFM72690.1 - 0.043 13.9 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Swi3 PF07962.12 KFM72692.1 - 3.6e-06 26.9 0.0 9.3e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 YtfJ_HI0045 PF09695.10 KFM72692.1 - 0.12 12.0 1.9 0.16 11.6 0.3 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (YtfJ_HI0045) DDE_Tnp_1_7 PF13843.6 KFM72693.1 - 6.5e-06 25.7 0.0 7.7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 HTH_Tnp_Tc3_2 PF01498.18 KFM72694.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72694.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72694.1 - 2e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72694.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72694.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RVT_1 PF00078.27 KFM72695.1 - 4.5e-05 23.1 0.0 4.8e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HECT PF00632.25 KFM72696.1 - 3.4e-76 256.7 0.0 5.6e-76 255.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 KFM72696.1 - 1.2e-23 83.2 1.8 2.4e-23 82.2 1.8 1.6 1 0 0 1 1 1 1 Mib_herc2 SDA1 PF05285.12 KFM72696.1 - 0.38 10.1 4.2 4.3 6.7 2.9 2.4 2 0 0 2 2 2 0 SDA1 Trypsin PF00089.26 KFM72697.1 - 1.8e-63 214.3 0.1 4.7e-63 213.0 0.1 1.7 1 0 0 1 1 1 1 Trypsin Sushi PF00084.20 KFM72697.1 - 5.5e-41 139.0 25.1 3.6e-11 43.5 0.3 6.8 6 0 0 6 6 6 5 Sushi repeat (SCR repeat) LCCL PF03815.19 KFM72697.1 - 1.4e-21 76.3 0.2 4.9e-21 74.6 0.2 1.9 1 0 0 1 1 1 1 LCCL domain Skp1 PF01466.19 KFM72697.1 - 0.0035 17.4 0.1 0.0068 16.5 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain DUF1986 PF09342.11 KFM72697.1 - 0.0038 17.6 0.0 0.0081 16.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFM72697.1 - 0.0043 18.0 0.0 0.012 16.5 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain ATP-gua_Ptrans PF00217.19 KFM72697.1 - 0.047 13.2 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain DUF1279 PF06916.13 KFM72698.1 - 3.3e-09 37.2 0.1 1.2e-08 35.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) GRDP-like PF07173.12 KFM72698.1 - 0.012 16.2 0.1 0.014 16.1 0.1 1.2 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like Tom22 PF04281.13 KFM72699.1 - 1.8e-13 50.4 1.1 2.4e-13 50.0 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 LCAT PF02450.15 KFM72700.1 - 2e-68 231.4 0.8 1.1e-66 225.6 0.8 2.1 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KFM72700.1 - 1.2e-05 24.8 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM72700.1 - 0.052 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KFM72700.1 - 0.065 12.9 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein DUF676 PF05057.14 KFM72700.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 KFM72700.1 - 0.094 12.6 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Cyclase PF04199.13 KFM72704.1 - 2.5e-35 121.7 0.1 3.4e-35 121.3 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.13 KFM72705.1 - 2.2e-24 86.2 0.0 2.6e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.13 KFM72706.1 - 1.4e-32 112.7 0.3 1.8e-32 112.4 0.3 1.1 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.13 KFM72707.1 - 4e-36 124.3 0.2 5e-36 123.9 0.2 1.1 1 0 0 1 1 1 1 Putative cyclase Cullin PF00888.22 KFM72708.1 - 2e-208 694.0 14.2 2.4e-208 693.7 14.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFM72708.1 - 2.8e-21 75.3 1.1 2.8e-21 75.3 1.1 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain Ndc80_HEC PF03801.13 KFM72709.1 - 9.4e-23 80.5 0.6 9.4e-23 80.5 0.6 3.2 3 0 0 3 3 3 1 HEC/Ndc80p family CBM_14 PF01607.24 KFM72710.1 - 1.8e-92 303.4 154.7 6.8e-13 48.6 3.1 10.3 10 0 0 10 10 10 10 Chitin binding Peritrophin-A domain Mucin PF01456.17 KFM72710.1 - 0.0057 16.7 2.1 0.0057 16.7 2.1 3.3 2 1 1 3 3 3 1 Mucin-like glycoprotein CBM_14 PF01607.24 KFM72711.1 - 3.6e-39 132.7 53.1 8.2e-12 45.1 3.3 4.4 4 0 0 4 4 4 4 Chitin binding Peritrophin-A domain RolB_RolC PF02027.17 KFM72711.1 - 0.00052 19.7 0.1 1.2 8.7 0.0 2.8 2 0 0 2 2 2 2 RolB/RolC glucosidase family DUF3122 PF11320.8 KFM72711.1 - 0.033 14.3 12.8 4 7.5 0.0 6.7 8 0 0 8 8 8 0 Protein of unknown function (DUF3122) Rap_GAP PF02145.15 KFM72712.1 - 1.2e-67 227.0 0.4 1.9e-67 226.4 0.4 1.3 1 0 0 1 1 1 1 Rap/ran-GAP CNH PF00780.22 KFM72712.1 - 3.1e-54 184.5 0.1 7.4e-54 183.2 0.0 1.6 2 0 0 2 2 2 1 CNH domain Peptidase_C97 PF05903.14 KFM72716.1 - 2e-12 47.2 0.0 2.2e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain YHS PF04945.13 KFM72716.1 - 0.17 12.0 0.5 0.27 11.4 0.5 1.3 1 0 0 1 1 1 0 YHS domain DUF4371 PF14291.6 KFM72717.1 - 7.2e-10 38.9 0.1 1e-09 38.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Kelch_1 PF01344.25 KFM72719.1 - 1.2e-91 300.1 21.9 1.3e-16 59.9 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFM72719.1 - 9.7e-37 124.1 8.1 4.2e-06 26.9 0.0 6.6 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFM72719.1 - 4.9e-35 118.2 11.9 5.2e-06 26.2 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFM72719.1 - 4.8e-31 106.5 9.0 1.9e-05 24.6 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFM72719.1 - 4e-26 90.7 12.0 6.9e-06 26.2 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFM72719.1 - 1.2e-20 73.8 0.1 2.3e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM72719.1 - 5.3e-06 26.5 0.2 1.1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 KFM72719.1 - 7.7e-06 25.8 12.3 0.2 11.7 0.0 6.3 6 0 0 6 6 6 2 Kelch motif PQQ_3 PF13570.6 KFM72719.1 - 0.013 15.9 9.8 1.4 9.5 0.2 5.1 6 0 0 6 6 5 0 PQQ-like domain WYL_2 PF10902.8 KFM72719.1 - 0.021 15.2 0.1 14 6.1 0.0 3.6 3 0 0 3 3 3 0 WYL_2, Sm-like SH3 beta-barrel fold Glyoxal_oxid_N PF07250.11 KFM72719.1 - 0.46 9.6 3.8 1.5 8.0 0.1 2.7 1 1 1 2 2 2 0 Glyoxal oxidase N-terminus Transposase_1 PF01359.18 KFM72720.1 - 2.2e-22 78.6 0.7 3.7e-22 77.9 0.7 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM72720.1 - 0.0066 16.2 0.2 0.009 15.8 0.2 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Sulfotransfer_2 PF03567.14 KFM72721.1 - 1.3e-33 117.0 0.4 1.7e-33 116.6 0.4 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM72721.1 - 0.07 12.6 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 Sulfotransferase domain SET PF00856.28 KFM72722.1 - 3.1e-19 70.0 0.1 1.9e-18 67.4 0.1 2.2 1 1 0 1 1 1 1 SET domain ATG11 PF10377.9 KFM72722.1 - 0.036 14.1 0.2 0.12 12.5 0.2 2.0 1 1 0 1 1 1 0 Autophagy-related protein 11 XRN_N PF03159.18 KFM72723.1 - 3.1e-95 318.2 0.0 4.8e-95 317.6 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KFM72723.1 - 6.3e-25 88.0 0.8 8.6e-25 87.6 0.8 1.1 1 0 0 1 1 1 1 Xrn1 helical domain HSF_DNA-bind PF00447.17 KFM72723.1 - 0.063 13.9 0.2 0.19 12.4 0.2 1.8 1 0 0 1 1 1 0 HSF-type DNA-binding XRN1_D1 PF18332.1 KFM72724.1 - 1.7e-36 125.8 0.4 3.5e-36 124.8 0.4 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 KFM72724.1 - 1.4e-19 69.9 0.0 6.4e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 KFM72724.1 - 1.2e-07 31.8 0.1 9.8e-07 28.9 0.0 2.5 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain EGF_CA PF07645.15 KFM72725.1 - 1.4e-71 236.4 128.1 7.5e-11 42.1 5.4 9.9 10 0 0 10 10 10 9 Calcium-binding EGF domain cEGF PF12662.7 KFM72725.1 - 8e-47 156.8 89.0 1.3e-10 41.0 1.6 11.5 11 0 0 11 11 11 10 Complement Clr-like EGF-like G2F PF07474.12 KFM72725.1 - 1.1e-45 155.7 0.0 2.1e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 G2F domain FXa_inhibition PF14670.6 KFM72725.1 - 2.2e-37 127.0 117.0 8.8e-08 32.3 8.6 10.9 9 1 1 10 10 10 7 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFM72725.1 - 1e-13 51.2 102.9 0.003 17.7 7.1 10.5 9 2 0 9 9 9 8 EGF domain EGF PF00008.27 KFM72725.1 - 2e-12 47.1 107.2 0.00021 21.5 5.3 10.4 9 1 0 9 9 9 6 EGF-like domain TSP_1 PF00090.19 KFM72725.1 - 1.7e-08 34.6 3.1 1.7e-08 34.6 3.1 3.9 3 0 0 3 3 3 1 Thrombospondin type 1 domain hEGF PF12661.7 KFM72725.1 - 3.4e-05 24.3 85.0 0.044 14.4 2.0 11.5 10 0 0 10 10 10 5 Human growth factor-like EGF Cadherin PF00028.17 KFM72725.1 - 0.0036 17.7 0.1 0.0084 16.5 0.1 1.6 1 0 0 1 1 1 1 Cadherin domain EGF_MSP1_1 PF12946.7 KFM72725.1 - 0.0069 16.4 3.2 0.0069 16.4 3.2 10.5 9 2 1 10 10 10 4 MSP1 EGF domain 1 V-set PF07686.17 KFM72726.1 - 7.9e-10 38.9 0.0 9.9e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM72726.1 - 1.5e-06 28.7 0.0 2.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM72726.1 - 6.8e-05 22.9 0.0 0.00022 21.3 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM72726.1 - 0.00015 22.0 0.0 0.00058 20.2 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM72726.1 - 0.0003 20.9 0.0 0.0012 18.9 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFM72726.1 - 0.0004 19.9 0.0 0.00074 19.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM72726.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain CHD5 PF04420.14 KFM72727.1 - 4.4e-28 98.1 0.1 5.7e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 CHD5-like protein Voltage_CLC PF00654.20 KFM72727.1 - 0.54 9.4 6.8 2.6 7.2 6.8 2.1 1 1 0 1 1 1 0 Voltage gated chloride channel RCC1 PF00415.18 KFM72728.1 - 1.9e-33 114.9 10.5 2.8e-08 34.3 0.2 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM72728.1 - 7.6e-20 70.2 19.1 4.7e-08 32.6 1.1 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PagP PF07017.11 KFM72728.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Ribosomal_L27 PF01016.19 KFM72728.1 - 0.1 12.6 0.3 0.96 9.5 0.0 2.5 3 0 0 3 3 3 0 Ribosomal L27 protein FlaC_arch PF05377.11 KFM72729.1 - 0.048 14.0 1.9 0.19 12.2 0.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FliJ PF02050.16 KFM72729.1 - 0.083 13.1 4.2 0.61 10.3 1.4 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein T2SSG PF08334.11 KFM72729.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G ADIP PF11559.8 KFM72729.1 - 0.29 11.2 12.2 0.028 14.5 7.6 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 KFM72729.1 - 0.55 10.7 6.2 0.83 10.2 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Bcr-Abl_Oligo PF09036.10 KFM72729.1 - 1.2 9.2 8.0 2.4 8.2 0.6 3.1 2 1 2 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain HTH_Tnp_Tc3_2 PF01498.18 KFM72731.1 - 2.3e-16 59.8 2.2 5e-16 58.7 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72731.1 - 1.1e-13 51.1 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_48 PF17906.1 KFM72731.1 - 2.1e-06 27.7 0.1 4.2e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase RBD PF02196.15 KFM72732.1 - 1.7e-08 34.4 0.4 0.00057 19.9 0.0 3.1 3 0 0 3 3 3 2 Raf-like Ras-binding domain Cobl PF09469.10 KFM72732.1 - 0.0013 18.9 0.0 0.0049 17.1 0.0 1.9 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain TUG-UBL1 PF11470.8 KFM72732.1 - 0.005 17.0 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 2 TUG ubiquitin-like domain HECT PF00632.25 KFM72733.1 - 2.1e-57 194.9 0.0 3.5e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 KFM72733.1 - 8.7e-32 109.5 5.8 1.1e-14 54.8 0.1 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM72733.1 - 2.3e-13 49.6 10.7 4.1e-06 26.4 0.2 3.6 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat HTH_Tnp_Tc3_2 PF01498.18 KFM72734.1 - 4.8e-16 58.8 3.5 6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72734.1 - 5.6e-13 48.9 0.0 9.8e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72734.1 - 2.9e-07 30.2 1.6 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72734.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72734.1 - 2.2 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain SHMT PF00464.19 KFM72735.1 - 3.1e-202 671.4 0.0 3.7e-202 671.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 KFM72735.1 - 0.096 12.0 0.1 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Lipoprotein_16 PF03923.13 KFM72735.1 - 0.19 11.4 0.5 2.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized lipoprotein KH_1 PF00013.29 KFM72736.1 - 6.4e-56 186.1 13.2 2.9e-20 71.9 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFM72736.1 - 8.9e-16 57.5 7.3 4.3e-05 23.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFM72736.1 - 9.1e-09 35.1 3.1 0.054 13.4 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFM72736.1 - 6.4e-06 26.2 7.7 0.3 11.2 0.5 3.3 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KFM72736.1 - 0.014 15.3 0.0 0.92 9.6 0.0 2.7 3 0 0 3 3 3 0 KH-like RNA-binding domain Alba PF01918.21 KFM72736.1 - 0.034 14.0 0.3 2 8.3 0.0 2.8 3 0 0 3 3 3 0 Alba MFS_1 PF07690.16 KFM72738.1 - 1.3e-35 123.0 30.1 1.4e-32 113.1 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KFM72738.1 - 0.00035 19.1 4.1 0.08 11.3 0.2 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.19 KFM72738.1 - 0.00035 19.5 1.6 0.00035 19.5 1.6 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter MFS_4 PF06779.14 KFM72738.1 - 0.44 9.8 12.1 0.28 10.4 2.4 2.2 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB 7tm_1 PF00001.21 KFM72739.1 - 3.4e-27 95.4 16.4 4.5e-27 95.0 16.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM72739.1 - 0.0022 17.7 15.8 0.0022 17.7 15.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFM72739.1 - 0.0044 16.4 16.7 0.0061 16.0 16.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx HTH_Tnp_Tc3_2 PF01498.18 KFM72740.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72740.1 - 7.6e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72741.1 - 4.6e-16 58.8 3.5 5.6e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72741.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72741.1 - 2e-07 30.6 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72741.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72741.1 - 2.2 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HLH PF00010.26 KFM72742.1 - 2.5e-18 65.7 0.5 2.5e-18 65.7 0.5 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Atg14 PF10186.9 KFM72742.1 - 0.032 13.3 0.2 0.049 12.7 0.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Alpha-2-MRAP_C PF06401.11 KFM72742.1 - 0.11 12.4 0.2 0.16 11.9 0.2 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain PC4 PF02229.16 KFM72743.1 - 2.1e-26 91.3 0.1 3e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DTHCT PF08070.11 KFM72743.1 - 1.4 9.7 10.9 1.6 9.5 10.7 1.3 1 1 0 1 1 1 0 DTHCT (NUC029) region RVT_1 PF00078.27 KFM72744.1 - 0.0026 17.3 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Yos1 PF08571.10 KFM72745.1 - 1.8e-33 114.6 0.4 2e-33 114.5 0.4 1.0 1 0 0 1 1 1 1 Yos1-like MAT1 PF06391.13 KFM72747.1 - 0.024 14.5 13.5 0.025 14.4 13.5 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DDE_1 PF03184.19 KFM72749.1 - 3.5e-09 36.6 0.0 3.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72751.1 - 4.6e-16 58.8 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72751.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72751.1 - 2e-07 30.7 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72751.1 - 0.0027 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72751.1 - 0.022 14.9 0.4 0.092 12.9 0.4 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM72751.1 - 1.9 9.2 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM72752.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72752.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72753.1 - 4.1e-16 59.0 3.5 5.8e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72753.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72753.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72753.1 - 0.0027 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72753.1 - 2.2 9.0 15.6 0.12 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain SLATT_5 PF18160.1 KFM72754.1 - 0.028 13.7 2.6 0.04 13.3 2.6 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DDE_1 PF03184.19 KFM72755.1 - 1.4e-41 142.1 0.1 2.4e-41 141.3 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM72755.1 - 5.7e-15 55.1 0.3 1.7e-14 53.5 0.3 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM72755.1 - 9e-06 25.2 2.7 2.9e-05 23.6 2.7 1.9 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFM72755.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Ada3 PF10198.9 KFM72755.1 - 0.025 14.7 0.6 0.069 13.3 0.2 2.0 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 HTH_psq PF05225.16 KFM72755.1 - 0.028 14.1 0.0 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain DUF2181 PF10223.9 KFM72756.1 - 1.2e-50 172.2 0.0 1.3e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) DDE_3 PF13358.6 KFM72757.1 - 5.4e-16 58.7 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72757.1 - 7.5e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM72757.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM72757.1 - 0.0024 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72757.1 - 0.015 15.4 0.1 0.063 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM72757.1 - 0.033 14.2 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix CABIT PF12736.7 KFM72758.1 - 1.1e-42 146.3 0.0 2e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, DDE_3 PF13358.6 KFM72759.1 - 3.1e-12 46.5 0.0 4.3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Acyl-CoA_dh_1 PF00441.24 KFM72760.1 - 1.5e-22 80.4 0.0 3.5e-21 76.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM72760.1 - 2.8e-19 69.8 0.0 5.1e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM72760.1 - 7.9e-19 67.7 0.1 1.4e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM72760.1 - 6e-08 33.1 0.0 1.3e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_L18A PF01775.17 KFM72761.1 - 2.6e-56 188.9 0.3 3.1e-56 188.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF5496 PF17600.2 KFM72761.1 - 0.028 14.4 0.8 1.3 9.1 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5496) DUF1508 PF07411.12 KFM72761.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) CdvA PF18822.1 KFM72763.1 - 0.0019 18.0 9.7 0.25 11.2 1.4 2.6 2 0 0 2 2 2 2 CdvA-like coiled-coil domain HSBP1 PF06825.12 KFM72763.1 - 0.02 14.7 0.1 0.94 9.4 0.0 2.7 1 1 1 2 2 2 0 Heat shock factor binding protein 1 ApoO PF09769.9 KFM72763.1 - 0.024 14.6 1.6 0.12 12.3 0.3 2.3 1 1 1 2 2 2 0 Apolipoprotein O CHDCT2 PF08074.11 KFM72763.1 - 0.05 13.8 3.5 0.12 12.6 3.5 1.5 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Baculo_PEP_C PF04513.12 KFM72763.1 - 0.053 13.6 0.4 0.23 11.5 0.2 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DDE_Tnp_1_7 PF13843.6 KFM72763.1 - 0.06 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Transposase IS4 Apolipoprotein PF01442.18 KFM72763.1 - 0.17 11.7 9.5 0.083 12.8 6.7 2.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Peptidase_M75 PF09375.10 KFM72763.1 - 0.21 11.0 1.4 0.36 10.3 1.4 1.3 1 0 0 1 1 1 0 Imelysin CLZ PF16526.5 KFM72763.1 - 0.28 11.6 7.2 0.26 11.7 1.2 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels COG2 PF06148.11 KFM72763.1 - 0.4 10.8 11.2 0.41 10.7 2.3 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KFM72763.1 - 0.5 10.4 10.7 1.7 8.7 5.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Flagellar_rod PF05149.12 KFM72763.1 - 0.63 9.4 9.4 1.1 8.7 9.4 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein DUF4407 PF14362.6 KFM72763.1 - 0.8 9.0 5.1 1.6 8.0 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2_3rep PF18868.1 KFM72763.1 - 0.8 10.4 3.1 4.7 7.9 0.0 3.3 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats NPV_P10 PF05531.12 KFM72763.1 - 0.99 9.9 4.6 6.6 7.3 2.3 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF677 PF05055.12 KFM72763.1 - 1.2 8.0 12.2 2.1 7.2 12.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF677) IFT57 PF10498.9 KFM72763.1 - 1.2 8.0 14.7 0.51 9.3 8.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Prominin PF05478.11 KFM72763.1 - 1.2 7.0 6.9 4.2 5.2 6.4 1.8 1 1 0 1 1 1 0 Prominin DUF3135 PF11333.8 KFM72763.1 - 1.6 9.0 3.8 4 7.7 0.1 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF3135) ApoLp-III PF07464.11 KFM72763.1 - 3.2 7.8 14.5 8.4 6.5 12.1 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) eIF-4B PF06273.11 KFM72763.1 - 3.4 6.6 9.1 13 4.7 0.1 2.9 3 0 0 3 3 3 0 Plant specific eukaryotic initiation factor 4B Phasin PF05597.11 KFM72763.1 - 4.7 7.2 18.0 0.18 11.8 4.9 3.0 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Histone_HNS PF00816.21 KFM72763.1 - 5.5 7.9 8.8 30 5.5 2.9 2.8 3 0 0 3 3 2 0 H-NS histone family DUF1690 PF07956.11 KFM72763.1 - 6.8 7.1 15.2 17 5.8 0.2 2.9 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Transketolase_C PF02780.20 KFM72766.1 - 5.5e-40 136.1 0.0 9.9e-40 135.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KFM72766.1 - 7.4e-25 87.6 0.0 1.3e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 KFM72766.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Tnp_P_element PF12017.8 KFM72767.1 - 4.8e-39 134.1 0.0 5.3e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Transposase protein MAGE PF01454.19 KFM72768.1 - 3.9e-25 88.8 7.3 1.5e-16 60.8 0.0 2.7 2 2 1 3 3 3 2 MAGE family DTHCT PF08070.11 KFM72768.1 - 0.32 11.8 25.3 2.2 9.1 19.1 2.3 1 1 1 2 2 2 0 DTHCT (NUC029) region CDC45 PF02724.14 KFM72768.1 - 1.2 7.4 14.1 1.5 7.0 14.1 1.2 1 0 0 1 1 1 0 CDC45-like protein HTH_Tnp_Tc5 PF03221.16 KFM72769.1 - 2.5e-15 56.2 0.0 3.8e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM72770.1 - 1.4e-10 41.1 0.0 1.5e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HSCB_C PF07743.13 KFM72771.1 - 0.027 15.0 1.2 0.059 13.9 0.2 2.0 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF1664 PF07889.12 KFM72771.1 - 0.058 13.4 0.2 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 KFM72771.1 - 0.22 10.7 1.2 0.43 9.8 1.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein Snapin_Pallidin PF14712.6 KFM72771.1 - 0.45 11.0 2.3 0.74 10.3 0.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin YiaAB PF05360.14 KFM72773.1 - 0.019 15.2 0.0 0.027 14.7 0.0 1.3 1 1 0 1 1 1 0 yiaA/B two helix domain I-set PF07679.16 KFM72774.1 - 3.4e-39 132.8 0.0 2.6e-15 56.3 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM72774.1 - 1.4e-37 128.1 0.7 4.8e-15 55.9 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM72774.1 - 2.6e-26 91.8 0.1 3e-11 43.5 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM72774.1 - 7e-23 80.6 0.1 1.2e-06 28.6 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM72774.1 - 1e-14 54.6 1.2 0.017 15.3 0.2 5.1 4 1 0 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM72774.1 - 3.5e-08 33.4 0.1 0.0018 18.3 0.0 2.5 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM72774.1 - 9.8e-07 28.2 0.0 0.074 12.6 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain C1-set PF07654.15 KFM72774.1 - 1.9e-06 28.1 0.3 0.11 12.9 0.0 2.7 3 1 0 3 3 2 2 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM72774.1 - 4.2e-05 23.7 0.0 0.062 13.6 0.0 3.8 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM72774.1 - 0.0001 22.3 0.0 2.2 8.4 0.0 3.3 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFM72774.1 - 0.00029 21.2 0.0 0.15 12.5 0.0 3.5 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFM72774.1 - 0.012 15.6 0.0 2 8.5 0.0 2.7 3 0 0 3 3 3 0 C17orf99 Ig domain Ig_3 PF13927.6 KFM72775.1 - 1.1e-14 54.7 0.0 1.7e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM72775.1 - 3.5e-13 49.4 0.0 4.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM72775.1 - 2.9e-08 33.8 0.1 4.6e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM72775.1 - 5.6e-08 33.0 0.0 7.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM72775.1 - 3.4e-05 24.0 0.1 0.021 15.0 0.1 2.1 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM72775.1 - 0.0049 16.4 0.1 0.011 15.3 0.0 1.6 1 1 1 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM72775.1 - 0.007 16.4 0.0 0.011 15.8 0.0 1.4 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM72775.1 - 0.01 15.9 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFM72775.1 - 0.055 13.9 0.0 0.08 13.4 0.0 1.2 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM72775.1 - 0.074 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain fn3 PF00041.21 KFM72777.1 - 3.6e-08 33.6 1.5 1.3e-05 25.5 0.2 2.1 2 0 0 2 2 2 2 Fibronectin type III domain fn3_2 PF16893.5 KFM72777.1 - 0.007 16.5 1.1 3.3 7.9 0.1 2.1 2 0 0 2 2 2 2 Fibronectin type III domain fn3 PF00041.21 KFM72780.1 - 1.3e-35 121.5 10.2 4.7e-13 49.3 0.3 3.3 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM72780.1 - 7e-05 23.3 13.2 0.14 12.7 0.8 3.9 4 0 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain Shisa PF13908.6 KFM72780.1 - 0.0019 18.5 0.0 0.0055 17.0 0.0 1.9 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 KFM72780.1 - 0.0025 17.7 0.4 0.036 14.0 0.0 2.3 2 0 0 2 2 2 1 TMEM154 protein family fn3_2 PF16893.5 KFM72780.1 - 0.003 17.7 0.5 0.065 13.4 0.0 2.6 3 0 0 3 3 3 1 Fibronectin type III domain DUF4998 PF16389.5 KFM72780.1 - 0.0033 17.0 0.4 0.0058 16.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function Cadherin_C_2 PF16492.5 KFM72780.1 - 0.0047 17.7 0.1 0.045 14.5 0.0 2.4 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal Interfer-bind PF09294.10 KFM72780.1 - 0.0073 16.6 1.1 15 5.9 0.1 3.5 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III DUF1180 PF06679.12 KFM72780.1 - 0.0075 16.7 0.1 0.0075 16.7 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1180) TMEM174 PF15029.6 KFM72780.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 SusE PF14292.6 KFM72780.1 - 0.022 15.0 0.1 0.067 13.4 0.1 1.8 1 0 0 1 1 1 0 SusE outer membrane protein SIT PF15330.6 KFM72780.1 - 0.05 14.1 0.0 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT EphA2_TM PF14575.6 KFM72780.1 - 0.061 14.2 0.0 0.16 12.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F5_F8_type_C PF00754.25 KFM72780.1 - 0.084 13.0 0.2 0.084 13.0 0.2 2.8 4 1 0 4 4 4 0 F5/8 type C domain Ig_3 PF13927.6 KFM72782.1 - 1.3e-13 51.3 0.1 3.5e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM72782.1 - 3.8e-11 42.9 0.0 2.3e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFM72782.1 - 8.2e-07 29.1 0.4 9.7e-05 22.5 0.2 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM72782.1 - 7.2e-06 26.3 0.1 3.5e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM72782.1 - 0.0079 16.2 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM72782.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.5 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain HTH_Tnp_Tc3_2 PF01498.18 KFM72783.1 - 2.1e-16 59.9 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72783.1 - 7.8e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72784.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72784.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72784.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72784.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72784.1 - 2 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain PH PF00169.29 KFM72785.1 - 6.9e-20 71.5 0.1 1.2e-13 51.4 0.0 2.1 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFM72785.1 - 2.1e-06 28.1 8.3 0.028 14.9 0.9 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KFM72785.1 - 5.8e-05 23.4 1.5 0.0091 16.4 0.0 3.0 2 1 1 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 KFM72785.1 - 0.0066 16.7 2.7 0.7 10.2 0.0 2.4 2 1 0 2 2 2 2 Pleckstrin homology domain DDE_1 PF03184.19 KFM72786.1 - 4.1e-50 169.8 0.1 7.8e-50 168.9 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM72786.1 - 2e-12 47.0 0.0 1.6e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM72786.1 - 0.0011 18.6 0.0 0.0032 17.1 0.0 1.9 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM72787.1 - 3.9e-16 59.1 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72787.1 - 2.9e-13 49.8 0.0 5.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72787.1 - 3.1e-07 30.1 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72787.1 - 0.0028 17.4 0.6 0.0082 15.9 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72787.1 - 2.6 8.7 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Calpain_III PF01067.22 KFM72788.1 - 1.7e-24 86.7 0.1 1.9e-24 86.5 0.1 1.0 1 0 0 1 1 1 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 KFM72789.1 - 2.2e-104 348.7 0.0 2.5e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease DDE_3 PF13358.6 KFM72790.1 - 2.9e-16 59.5 0.1 3.1e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72790.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM72791.1 - 2.2e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72791.1 - 5.5e-14 52.1 0.0 8.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72792.1 - 4.9e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72792.1 - 1.3e-13 51.0 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72792.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72792.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72792.1 - 2.6 8.7 15.3 0.12 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain WW PF00397.26 KFM72793.1 - 4e-10 39.6 2.0 8.4e-10 38.6 2.0 1.6 1 0 0 1 1 1 1 WW domain Red1 PF07964.11 KFM72793.1 - 0.049 11.9 1.3 0.066 11.5 1.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 CDC45 PF02724.14 KFM72793.1 - 0.5 8.6 6.5 0.77 8.0 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 KFM72793.1 - 4.1 7.1 8.8 0.19 11.5 2.0 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Pkinase PF00069.25 KFM72795.1 - 4.5e-58 196.7 0.5 4.4e-41 141.0 0.4 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM72795.1 - 1.4e-27 96.7 0.1 8.2e-20 71.2 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM72795.1 - 1.2e-07 31.1 2.9 1.2e-07 31.1 2.9 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KFM72795.1 - 0.00024 20.5 0.4 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFM72795.1 - 0.0026 17.7 1.5 0.018 15.0 0.2 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM72795.1 - 0.021 14.2 0.7 0.065 12.6 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFM72795.1 - 0.027 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 KFM72795.1 - 0.085 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DKNYY PF13644.6 KFM72795.1 - 1 10.2 3.0 4.3 8.1 2.9 1.9 1 1 0 1 1 1 0 DKNYY family DUF1856 PF08983.10 KFM72797.1 - 0.043 14.0 0.0 0.053 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) IL4_i_Ig PF18258.1 KFM72797.1 - 0.079 13.2 0.0 0.088 13.0 0.0 1.1 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain WD40 PF00400.32 KFM72797.1 - 0.089 13.7 1.4 0.12 13.3 0.6 1.6 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-C2H2_4 PF13894.6 KFM72799.1 - 1.2e-06 28.9 25.6 0.089 13.7 0.2 6.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM72799.1 - 2.3e-06 27.8 15.0 0.22 12.0 0.2 5.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM72799.1 - 7.3e-05 22.9 12.6 0.55 10.6 0.0 5.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM72799.1 - 9e-05 22.7 18.1 0.098 13.1 0.1 5.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type DUF5301 PF17225.3 KFM72799.1 - 0.61 10.6 5.2 0.78 10.2 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) Prok-RING_1 PF14446.6 KFM72799.1 - 1.4 8.9 9.7 7.1 6.6 0.3 4.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 C1_4 PF07975.12 KFM72799.1 - 2.9 8.2 20.2 0.067 13.4 9.1 4.2 3 1 0 3 3 3 0 TFIIH C1-like domain DUF1168 PF06658.12 KFM72800.1 - 0.37 10.6 29.6 12 5.7 29.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1168) Nop25 PF09805.9 KFM72800.1 - 1.3 9.5 20.5 1.4 9.4 20.5 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SURF2 PF05477.11 KFM72800.1 - 6.2 6.4 17.6 7.1 6.2 17.6 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) FAM60A PF15396.6 KFM72800.1 - 8.3 6.3 14.5 11 5.9 14.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A HTH_Tnp_Tc3_2 PF01498.18 KFM72802.1 - 5.4e-16 58.6 3.5 6.2e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72802.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72802.1 - 7.5e-07 28.8 0.2 7.5e-07 28.8 0.2 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72802.1 - 0.0029 17.3 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72802.1 - 2.9 8.6 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DSS1_SEM1 PF05160.13 KFM72803.1 - 1.2e-22 79.7 20.6 1.5e-22 79.4 20.6 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 KFM72803.1 - 0.0033 17.3 3.2 0.0035 17.2 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) DNA_pol_phi PF04931.13 KFM72803.1 - 1.5 6.8 7.2 1.5 6.9 7.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Pescadillo_N PF06732.11 KFM72804.1 - 4.2e-21 75.7 0.1 1.1e-20 74.4 0.1 1.7 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 KFM72804.1 - 1.1e-08 35.3 0.0 2.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFM72804.1 - 0.00013 22.2 0.0 0.00044 20.5 0.0 1.9 1 1 0 1 1 1 1 DNA ligase 3 BRCT domain KNTase_C PF07827.11 KFM72804.1 - 0.055 13.3 0.2 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 KNTase C-terminal domain YqfQ PF14181.6 KFM72804.1 - 0.42 10.8 7.9 3.9 7.6 5.3 2.2 2 0 0 2 2 2 0 YqfQ-like protein 7tm_1 PF00001.21 KFM72805.1 - 9.6e-32 110.3 1.0 1.3e-31 109.9 1.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM72805.1 - 7.3e-05 22.3 0.3 0.00011 21.6 0.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFM72805.1 - 0.017 14.4 1.5 0.12 11.6 0.1 2.1 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw TAS2R PF05296.13 KFM72805.1 - 0.027 13.6 1.0 0.21 10.6 0.1 2.0 1 1 0 2 2 2 0 Taste receptor protein (TAS2R) Thiolase_N PF00108.23 KFM72806.1 - 1.2e-89 300.2 0.0 2.6e-89 299.0 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFM72806.1 - 2.4e-47 159.6 0.5 4.9e-47 158.6 0.2 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFM72806.1 - 0.0034 17.0 1.1 0.0034 17.0 1.1 2.8 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain TMEM65 PF10507.9 KFM72807.1 - 9.5e-47 157.5 1.7 1.3e-46 157.0 1.7 1.2 1 0 0 1 1 1 1 Transmembrane protein 65 Sushi PF00084.20 KFM72810.1 - 1.7e-43 147.0 14.5 8.9e-11 42.2 0.5 4.0 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) HRM PF02793.22 KFM72810.1 - 1.8e-06 28.1 14.6 0.5 10.7 0.2 4.4 4 1 0 4 4 4 4 Hormone receptor domain VERL PF11386.8 KFM72810.1 - 0.12 12.6 5.3 3.3 7.9 0.3 3.2 3 0 0 3 3 3 0 Vitelline envelope receptor for lysin Myb_Cef PF11831.8 KFM72811.1 - 6.5e-74 248.5 11.0 6.5e-74 248.5 11.0 4.0 5 1 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KFM72811.1 - 2.5e-20 72.4 6.1 1.3e-11 44.5 1.9 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM72811.1 - 4.1e-19 68.6 4.5 6.7e-13 48.7 3.7 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KFM72811.1 - 4.5 7.4 7.8 0.2 11.8 0.2 2.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pox_A_type_inc PF04508.12 KFM72811.1 - 5 7.1 7.7 1.6 8.7 1.7 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CDC27 PF09507.10 KFM72812.1 - 1.5e-14 54.3 44.9 1.8e-14 54.0 44.9 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 CDC27 PF09507.10 KFM72813.1 - 5.7e-29 101.7 1.5 6.5e-29 101.6 1.5 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-H2C2_2 PF13465.6 KFM72814.1 - 1.8e-39 132.4 79.9 2.4e-06 27.7 0.6 13.4 13 0 0 13 13 13 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72814.1 - 3.1e-36 121.8 105.5 8.6e-05 22.8 4.1 12.3 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72814.1 - 4e-33 111.2 91.4 0.00039 21.0 2.3 12.3 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM72814.1 - 1e-16 60.7 57.9 0.0045 17.2 0.6 11.9 10 2 2 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM72814.1 - 5.2e-15 55.3 73.3 0.016 15.6 1.5 12.6 13 1 1 14 14 14 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM72814.1 - 1.2e-08 34.8 80.6 0.0042 17.0 0.3 12.3 12 0 0 12 12 12 5 C2H2-type zinc finger zf-Di19 PF05605.12 KFM72814.1 - 9.6e-07 29.0 59.9 0.014 15.7 7.7 7.6 4 2 5 9 9 9 6 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KFM72814.1 - 0.0042 17.5 37.6 0.06 13.8 0.5 9.0 10 0 0 10 10 10 3 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_11 PF16622.5 KFM72814.1 - 0.0051 16.5 3.6 0.0051 16.5 3.6 9.6 11 1 1 12 12 11 3 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM72814.1 - 0.0083 16.0 54.7 0.027 14.3 0.0 11.1 12 0 0 12 12 12 3 zinc-finger of a C2HC-type Elf1 PF05129.13 KFM72814.1 - 0.018 15.1 2.8 0.018 15.1 2.8 7.4 2 2 7 9 9 9 0 Transcription elongation factor Elf1 like BolA PF01722.18 KFM72814.1 - 0.039 14.2 17.2 0.67 10.3 0.5 5.3 3 1 2 5 5 5 0 BolA-like protein Pneumo_ncap PF03246.13 KFM72814.1 - 0.046 12.5 0.2 0.083 11.6 0.2 1.3 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein zf-H2C2_5 PF13909.6 KFM72814.1 - 0.18 11.6 0.1 0.18 11.6 0.1 9.8 11 0 0 11 11 11 0 C2H2-type zinc-finger domain C1_1 PF00130.22 KFM72814.1 - 0.18 11.7 0.2 0.18 11.7 0.2 8.8 4 2 5 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFM72814.1 - 1.2 10.0 49.9 3.1 8.6 1.7 7.0 2 2 5 7 7 6 0 zinc-ribbon family zinc_ribbon_4 PF13717.6 KFM72814.1 - 3.3 7.7 0.0 3.3 7.7 0.0 8.9 10 2 1 11 11 10 0 zinc-ribbon domain ADK_lid PF05191.14 KFM72814.1 - 6.9 6.8 40.7 0.6 10.1 0.7 8.1 6 4 2 8 8 8 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 KFM72814.1 - 8.4 6.6 47.0 2.3 8.4 1.2 8.7 4 3 6 10 10 10 0 Zinc ribbon domain GAGA PF09237.11 KFM72814.1 - 8.5 6.3 34.9 0.14 12.0 1.8 6.8 4 2 5 9 9 8 0 GAGA factor HTH_Tnp_Tc3_2 PF01498.18 KFM72815.1 - 5.2e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72815.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72815.1 - 2.2e-07 30.5 1.2 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72815.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72815.1 - 0.028 14.6 0.4 0.094 12.9 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM72815.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM72816.1 - 2.5e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72816.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM72817.1 - 3.5e-12 46.2 0.4 6.7e-12 45.3 0.4 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KFM72817.1 - 1.3e-09 38.0 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM72817.1 - 0.0066 16.2 0.0 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3372 PF11852.8 KFM72817.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Tox-GHH PF15636.6 KFM72818.1 - 3.8e-31 106.9 0.5 3.8e-31 106.9 0.5 1.7 2 0 0 2 2 2 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin RHS_repeat PF05593.14 KFM72818.1 - 2.4e-08 34.3 16.3 0.058 13.9 0.0 8.9 9 1 0 9 9 9 2 RHS Repeat DUF4595 PF15283.6 KFM72818.1 - 0.00037 20.6 5.1 0.56 10.2 0.2 4.5 3 1 1 4 4 4 2 Domain of unknown function (DUF4595) with porin-like fold FliC PF12445.8 KFM72818.1 - 0.22 11.9 0.8 0.57 10.5 0.8 1.7 1 0 0 1 1 1 0 Flagellin protein polyprenyl_synt PF00348.17 KFM72819.1 - 1.3e-69 234.2 0.5 1.5e-69 233.9 0.5 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KFM72819.1 - 0.01 15.4 0.5 0.015 14.9 0.5 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 HEAT_PBS PF03130.16 KFM72819.1 - 0.17 12.6 0.8 0.45 11.3 0.8 1.8 1 0 0 1 1 1 0 PBS lyase HEAT-like repeat HTH_33 PF13592.6 KFM72820.1 - 0.04 13.6 0.1 0.068 12.8 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix ERAP1_C PF11838.8 KFM72821.1 - 0.00017 21.2 0.0 0.00023 20.8 0.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Tnp_P_element PF12017.8 KFM72822.1 - 1.1e-15 57.7 1.1 2.5e-15 56.5 1.1 1.6 1 0 0 1 1 1 1 Transposase protein THAP PF05485.12 KFM72822.1 - 3.9e-14 53.4 0.6 3.9e-14 53.4 0.6 2.3 2 0 0 2 2 2 1 THAP domain Peptidase_M1 PF01433.20 KFM72823.1 - 9.6e-69 231.3 7.8 1.2e-68 230.9 7.8 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFM72823.1 - 3.9e-29 102.2 0.7 6.8e-29 101.4 0.7 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Aminopep PF10023.9 KFM72823.1 - 0.016 14.5 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Putative aminopeptidase Peptidase_M48 PF01435.18 KFM72823.1 - 0.023 14.5 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_M1_N PF17900.1 KFM72824.1 - 9.3e-51 172.7 0.8 1.2e-50 172.3 0.8 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF5060 PF16586.5 KFM72824.1 - 0.055 13.8 0.4 0.22 11.9 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5060) Fimbrial_PilY2 PF14481.6 KFM72824.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 DUF5641 PF18701.1 KFM72825.1 - 5.9e-14 52.0 0.0 6.6e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5641) HTH_Tnp_Tc3_2 PF01498.18 KFM72826.1 - 2.1e-16 59.9 2.2 4.4e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72826.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease FAD_binding_1 PF00667.20 KFM72827.1 - 1.4e-35 122.9 0.0 2.1e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KFM72827.1 - 7.1e-16 58.8 0.0 2.3e-15 57.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SIS_2 PF13580.6 KFM72827.1 - 0.011 15.8 0.1 0.034 14.2 0.1 1.8 2 0 0 2 2 2 0 SIS domain EF-hand_10 PF14788.6 KFM72827.1 - 0.19 11.6 1.5 3.6 7.5 0.0 2.9 3 0 0 3 3 3 0 EF hand Zn_ribbon_recom PF13408.6 KFM72829.1 - 0.053 14.0 0.7 11 6.7 0.0 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Pkinase_Tyr PF07714.17 KFM72830.1 - 9.8e-96 320.0 0.0 1.3e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM72830.1 - 1.1e-41 143.0 0.0 1.6e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 KFM72830.1 - 1.4e-21 76.6 3.4 4.6e-21 74.9 3.4 2.0 1 0 0 1 1 1 1 Kringle domain Fz PF01392.22 KFM72830.1 - 2.4e-09 37.8 3.3 6.5e-09 36.4 3.3 1.8 1 0 0 1 1 1 1 Fz domain Haspin_kinase PF12330.8 KFM72830.1 - 0.095 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PP2C_2 PF13672.6 KFM72831.1 - 6.6e-13 48.8 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFM72831.1 - 0.0074 16.2 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) SARS_lipid_bind PF09399.10 KFM72831.1 - 0.078 13.2 0.0 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 SARS lipid binding protein zf-H2C2_2 PF13465.6 KFM72832.1 - 4.9e-73 238.5 72.8 1e-08 35.2 0.9 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72832.1 - 3.9e-50 165.6 86.0 9e-06 25.9 0.8 12.2 12 0 0 12 12 12 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72832.1 - 4.9e-39 129.6 83.5 0.00033 21.2 0.6 12.1 12 0 0 12 12 12 10 C2H2-type zinc finger zf-met PF12874.7 KFM72832.1 - 3.1e-21 75.1 60.9 0.012 16.0 0.5 11.0 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM72832.1 - 2.2e-18 65.8 72.0 0.0082 16.1 4.2 11.2 11 0 0 11 11 11 9 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM72832.1 - 1.8e-14 53.2 61.6 0.037 13.8 0.1 12.1 12 0 0 12 12 12 7 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM72832.1 - 4.1e-12 46.0 54.7 0.0096 16.2 1.7 10.8 9 1 1 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM72832.1 - 3.2e-10 39.6 38.4 0.4 10.6 0.1 10.7 10 0 0 10 10 10 4 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM72832.1 - 1e-09 38.2 24.1 0.15 12.1 1.1 7.2 4 2 2 6 6 6 4 Adenylate kinase, active site lid BolA PF01722.18 KFM72832.1 - 2.7e-08 33.9 20.1 0.047 14.0 0.0 6.6 1 1 5 6 6 6 3 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM72832.1 - 4.2e-07 29.9 36.0 0.18 11.9 1.9 9.9 7 3 3 10 10 10 2 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM72832.1 - 7.5e-06 25.7 28.0 0.64 9.9 0.2 8.8 3 1 7 10 10 10 2 GAGA factor zf-C2H2_9 PF16293.5 KFM72832.1 - 1.5e-05 24.8 42.7 2.5 8.0 0.2 11.0 3 3 9 12 12 12 1 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM72832.1 - 5.3e-05 23.2 34.7 6 7.1 0.1 9.8 10 0 0 10 10 10 2 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM72832.1 - 8.5e-05 22.6 39.4 0.15 12.2 1.6 4.6 1 1 4 5 5 5 5 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_1 PF14446.6 KFM72832.1 - 0.003 17.4 33.5 10 6.2 0.1 9.8 10 0 0 10 10 10 0 Prokaryotic RING finger family 1 PqqA PF08042.11 KFM72832.1 - 0.0048 16.9 3.0 12 6.1 0.1 6.2 8 0 0 8 8 8 0 PqqA family HNH_5 PF14279.6 KFM72832.1 - 0.0078 16.1 40.1 5.4 6.9 0.4 9.1 6 3 2 8 8 8 1 HNH endonuclease TRAF6_Z2 PF18048.1 KFM72832.1 - 0.2 11.8 0.2 0.2 11.8 0.2 10.1 11 0 0 11 11 11 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_15 PF17032.5 KFM72832.1 - 0.22 12.3 39.1 1.8 9.3 2.9 6.2 1 1 4 7 7 7 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM72832.1 - 0.5 10.5 37.6 0.23 11.6 1.3 7.4 6 2 3 9 9 9 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KFM72832.1 - 0.65 10.4 68.5 1.4 9.3 2.0 9.3 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM72832.1 - 0.99 9.1 45.9 3.1 7.5 0.1 9.9 6 4 4 10 10 10 0 MYST family zinc finger domain DUF2256 PF10013.9 KFM72832.1 - 3.4 7.9 38.8 7.6 6.7 0.1 9.3 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) Macoilin PF09726.9 KFM72833.1 - 0.006 15.2 3.7 0.0065 15.1 3.7 1.0 1 0 0 1 1 1 1 Macoilin family LNP1 PF15419.6 KFM72833.1 - 0.0087 16.3 1.7 0.0087 16.3 1.7 1.4 2 0 0 2 2 2 1 Leukemia NUP98 fusion partner 1 Rhodanese PF00581.20 KFM72834.1 - 0.0014 19.2 0.0 0.0014 19.1 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain AA_permease PF00324.21 KFM72835.1 - 0.01 14.5 2.2 0.011 14.3 2.2 1.1 1 0 0 1 1 1 0 Amino acid permease O_anti_polymase PF01901.16 KFM72835.1 - 0.021 14.1 0.8 0.032 13.5 0.8 1.3 1 1 0 1 1 1 0 Putative O-antigen polymerase Claudin_3 PF06653.11 KFM72835.1 - 0.04 13.9 2.7 0.064 13.2 2.6 1.3 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Sid-5 PF17204.3 KFM72835.1 - 0.049 13.8 0.1 0.091 12.9 0.1 1.6 1 0 0 1 1 1 0 Sid-5 family Tetraspanin PF00335.20 KFM72835.1 - 0.38 10.4 2.8 2.1 8.0 0.1 2.0 1 1 0 2 2 2 0 Tetraspanin family ATP-synt_S1 PF05827.12 KFM72835.1 - 9.4 6.1 6.2 0.78 9.6 0.6 1.8 1 1 1 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) RVT_1 PF00078.27 KFM72836.1 - 0.0015 18.1 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chitin_bind_4 PF00379.23 KFM72837.1 - 1.7e-09 38.0 14.6 3.6e-09 37.0 14.6 1.6 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM72838.1 - 1.6e-12 47.7 9.2 3.3e-12 46.7 9.2 1.6 1 0 0 1 1 1 1 Insect cuticle protein Lectin_C PF00059.21 KFM72841.1 - 1.9e-15 57.5 0.1 4.7e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 Lectin C-type domain WSC PF01822.19 KFM72841.1 - 0.0021 18.2 4.8 0.0021 18.2 4.8 2.1 3 0 0 3 3 3 1 WSC domain SNF PF00209.18 KFM72842.1 - 3.6e-141 471.4 42.0 2.8e-139 465.2 42.0 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family HTH_Tnp_Tc3_2 PF01498.18 KFM72844.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72844.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72844.1 - 2.3e-05 24.1 0.4 0.00013 21.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM72845.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72845.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72845.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72845.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72845.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM72848.1 - 2.4e-16 59.7 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72848.1 - 9.6e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease LRR_6 PF13516.6 KFM72850.1 - 7.7e-12 44.3 1.5 0.19 11.9 0.0 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 KFM72850.1 - 2.7e-10 40.3 3.8 0.092 13.2 0.6 5.2 3 3 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM72850.1 - 4.3e-08 32.6 4.3 2.3 9.1 0.0 6.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.6 KFM72850.1 - 0.00012 21.8 4.3 0.97 9.2 0.0 4.2 3 2 0 3 3 3 2 Leucine rich repeat Gp58 PF07902.11 KFM72850.1 - 0.097 10.9 0.1 0.7 8.1 0.1 1.9 2 0 0 2 2 2 0 gp58-like protein F-box-like PF12937.7 KFM72851.1 - 4.5e-09 36.1 0.0 7.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM72851.1 - 1.6e-08 34.2 0.0 3.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KFM72851.1 - 3.4e-08 32.9 0.0 4.2e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 F-box LRR_4 PF12799.7 KFM72851.1 - 0.062 13.7 0.0 1.8 9.1 0.0 2.6 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) F-box_4 PF15966.5 KFM72851.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 F-box HTH_Tnp_Tc3_2 PF01498.18 KFM72853.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72853.1 - 7.6e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease BAR_3 PF16746.5 KFM72854.1 - 5.8e-05 22.9 9.8 7.9e-05 22.5 9.8 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Vps5 PF09325.10 KFM72854.1 - 0.00044 19.9 7.2 0.0015 18.1 7.2 1.7 1 1 0 1 1 1 1 Vps5 C terminal like DUF2989 PF11207.8 KFM72854.1 - 0.019 14.7 7.0 1 9.1 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2989) Bep_C_terminal PF17841.1 KFM72854.1 - 0.084 13.1 0.3 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) DUF632 PF04782.12 KFM72854.1 - 0.46 9.8 8.3 0.96 8.7 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF632) TFR_dimer PF04253.15 KFM72854.1 - 1.9 8.6 4.6 14 5.8 0.7 3.1 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain DUF737 PF05300.11 KFM72854.1 - 2.1 8.7 9.6 5.4 7.3 9.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF737) HDV_ag PF01517.18 KFM72854.1 - 6.2 6.6 7.3 10 5.8 0.6 2.8 2 1 1 3 3 3 0 Hepatitis delta virus delta antigen HECT PF00632.25 KFM72855.1 - 4.4e-65 220.2 0.0 4.8e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 KFM72856.1 - 4.1e-13 49.5 0.1 2.3e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) OrfB_Zn_ribbon PF07282.11 KFM72857.1 - 0.032 14.1 1.1 0.051 13.5 1.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.7 KFM72857.1 - 0.041 13.9 0.7 0.069 13.2 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon Rpr2 PF04032.16 KFM72857.1 - 0.11 12.8 0.3 0.3 11.4 0.3 1.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_L32p PF01783.23 KFM72857.1 - 0.38 11.1 1.7 1.1 9.6 0.1 2.4 3 0 0 3 3 3 0 Ribosomal L32p protein family YacG PF03884.14 KFM72857.1 - 0.38 10.5 3.6 0.65 9.8 3.6 1.3 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG zinc_ribbon_9 PF14369.6 KFM72857.1 - 0.52 10.6 4.6 8.7 6.7 1.1 2.6 1 1 1 2 2 2 0 zinc-ribbon zf-ribbon_3 PF13248.6 KFM72857.1 - 0.84 9.1 5.6 11 5.6 5.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain AA_permease_2 PF13520.6 KFM72858.1 - 1.4e-16 60.3 15.2 1.7e-16 60.1 15.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM72858.1 - 4e-05 22.4 11.2 5.2e-05 22.0 11.2 1.2 1 0 0 1 1 1 1 Amino acid permease SecG PF03840.14 KFM72858.1 - 0.039 14.0 0.2 0.14 12.2 0.2 2.0 1 0 0 1 1 1 0 Preprotein translocase SecG subunit GPR_Gpa2_C PF11970.8 KFM72858.1 - 6.1 7.0 7.8 2.3 8.4 0.8 2.8 3 1 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Fumble PF03630.14 KFM72859.1 - 3.5e-119 397.8 0.3 4.1e-119 397.6 0.3 1.0 1 0 0 1 1 1 1 Fumble WD40 PF00400.32 KFM72860.1 - 3e-13 50.0 6.4 0.0096 16.8 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Calreticulin PF00262.18 KFM72861.1 - 2.2e-140 467.7 10.9 2.6e-140 467.5 10.9 1.0 1 0 0 1 1 1 1 Calreticulin family End_beta_propel PF12217.8 KFM72861.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase HTH_Tnp_Tc3_2 PF01498.18 KFM72862.1 - 2e-16 60.0 2.2 4.2e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72862.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Astacin PF01400.24 KFM72864.1 - 2.6e-44 151.1 0.0 3.3e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM72864.1 - 0.04 13.8 0.1 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 Matrixin Astacin PF01400.24 KFM72865.1 - 2.8e-49 167.4 0.1 3.5e-49 167.0 0.1 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM72865.1 - 0.015 15.1 2.2 2.3 8.1 0.2 2.6 1 1 0 2 2 2 0 Matrixin DUF3361 PF11841.8 KFM72866.1 - 1.9e-59 200.0 2.0 3.1e-59 199.3 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) FERM_N PF09379.10 KFM72866.1 - 0.014 15.3 0.0 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 FERM N-terminal domain EFG_IV PF03764.18 KFM72866.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G, domain IV PH_12 PF16457.5 KFM72867.1 - 9.5e-40 136.2 0.0 2.2e-39 135.1 0.0 1.6 2 0 0 2 2 2 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 KFM72867.1 - 8.5e-25 87.9 0.1 1.8e-24 86.8 0.1 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family ZFYVE21_C PF16696.5 KFM72867.1 - 0.0097 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Zinc finger FYVE domain-containing protein 21 C-terminus MADF_DNA_bdg PF10545.9 KFM72868.1 - 6.6e-06 26.3 0.2 7.5e-06 26.2 0.2 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 KFM72868.1 - 0.014 15.7 0.4 0.015 15.7 0.4 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-CCHC_3 PF13917.6 KFM72869.1 - 0.15 12.1 0.1 0.42 10.6 0.1 1.7 2 0 0 2 2 2 0 Zinc knuckle AFP PF02420.15 KFM72871.1 - 0.12 12.8 1.1 10 6.9 0.2 2.4 2 0 0 2 2 2 0 Insect antifreeze protein repeat DnaJ PF00226.31 KFM72872.1 - 1.1e-23 83.1 2.1 1.1e-23 83.1 2.1 2.3 3 0 0 3 3 3 1 DnaJ domain RRM_1 PF00076.22 KFM72872.1 - 1.5e-06 27.9 0.3 5.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alpha_E3_glycop PF01563.16 KFM72872.1 - 0.014 15.5 0.0 0.04 14.0 0.0 1.8 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein SSI PF00720.17 KFM72872.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Subtilisin inhibitor-like PHM7_cyt PF14703.6 KFM72872.1 - 2.9 8.1 12.0 4.7 7.4 0.0 2.6 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter GFRP PF06399.13 KFM72873.1 - 4.8e-39 132.1 0.0 5.3e-39 132.0 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) eIF-5_eIF-2B PF01873.17 KFM72874.1 - 2.9e-40 136.8 0.2 8.9e-40 135.2 0.0 1.9 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 KFM72874.1 - 8.4e-24 83.5 3.4 2.4e-23 82.1 3.4 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF2387 PF09526.10 KFM72874.1 - 0.001 19.1 1.0 0.0055 16.8 0.0 2.4 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) Spectrin PF00435.21 KFM72874.1 - 0.027 15.0 1.2 0.027 15.0 1.2 2.2 2 0 0 2 2 2 0 Spectrin repeat Elf1 PF05129.13 KFM72874.1 - 1.3 9.1 4.8 1.3 9.2 0.1 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Cytomega_UL84 PF06284.11 KFM72874.1 - 4.7 5.5 6.8 2.2 6.6 0.8 2.0 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein CENP-B_dimeris PF09026.10 KFM72874.1 - 6.9 7.1 16.6 10 6.6 6.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HTH_Tnp_Tc3_2 PF01498.18 KFM72875.1 - 2.3e-16 59.8 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72875.1 - 9.9e-14 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM72876.1 - 2.7e-16 59.7 0.1 3.1e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72876.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72877.1 - 0.092 12.5 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72878.1 - 2.4e-16 59.7 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72878.1 - 9.7e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 KFM72879.1 - 0.036 13.6 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 KFM72880.1 - 0.054 13.3 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease RNA_GG_bind PF10258.9 KFM72881.1 - 1.1e-28 99.0 1.0 2.7e-28 97.8 1.0 1.7 1 0 0 1 1 1 1 PHAX RNA-binding domain Peptidase_S49_N PF08496.10 KFM72881.1 - 2.1 8.4 6.5 6.7 6.8 6.5 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RRM_1 PF00076.22 KFM72882.1 - 9e-44 147.2 1.3 4.8e-16 58.3 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM72882.1 - 8e-07 28.8 0.0 0.16 11.9 0.0 3.3 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_3 PF08777.11 KFM72882.1 - 6.4e-06 26.2 0.3 0.1 12.6 0.0 2.8 3 0 0 3 3 3 2 RNA binding motif RRM_5 PF13893.6 KFM72882.1 - 0.00013 21.6 0.1 0.086 12.4 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFM72882.1 - 0.01 15.9 0.1 1.1 9.3 0.0 2.8 2 1 0 2 2 2 1 Limkain b1 PseudoU_synth_2 PF00849.22 KFM72883.1 - 5.3e-30 104.6 0.0 9.1e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KFM72883.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 S4 domain FAD_oxidored PF12831.7 KFM72883.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF5104 PF17117.5 KFM72883.1 - 3.5 8.1 7.0 0.28 11.7 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5104) Elongin_A PF06881.11 KFM72886.1 - 0.00023 21.7 0.4 0.00037 21.0 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 KFM72886.1 - 0.037 13.9 0.1 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 F-box domain Not3 PF04065.15 KFM72887.1 - 1.8e-92 309.0 30.9 1.8e-92 309.0 30.9 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KFM72887.1 - 1.8e-30 105.7 4.7 1.8e-30 105.7 4.7 2.5 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family PI3K_P85_iSH2 PF16454.5 KFM72887.1 - 0.071 12.7 24.4 0.14 11.7 4.7 3.4 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain IGR PF09597.10 KFM72887.1 - 0.44 10.7 3.6 6.1 7.0 1.0 2.8 2 0 0 2 2 2 0 IGR protein motif PulA_N1 PF17999.1 KFM72887.1 - 4 8.3 5.5 1.3 9.8 1.3 2.5 2 1 0 2 2 2 0 Pullulanase N1-terminal domain Lectin_C PF00059.21 KFM72888.1 - 5e-10 40.1 0.2 2e-07 31.7 0.1 2.2 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 KFM72888.1 - 0.0056 16.4 0.0 0.58 9.8 0.0 2.1 2 0 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like DDE_3 PF13358.6 KFM72889.1 - 2.3e-10 40.4 0.0 2.7e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.6 KFM72890.1 - 6.2e-19 68.2 2.2 6.2e-19 68.2 2.2 2.9 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Glycos_transf_N PF04413.16 KFM72890.1 - 0.0004 20.1 0.0 0.00088 19.0 0.0 1.5 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Myb_DNA-binding PF00249.31 KFM72890.1 - 0.019 15.2 0.2 0.059 13.6 0.2 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain DUF573 PF04504.14 KFM72890.1 - 0.022 15.4 1.8 0.022 15.4 1.8 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.6 KFM72890.1 - 0.031 14.5 0.3 0.096 12.9 0.3 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM72890.1 - 0.07 13.4 0.6 0.07 13.4 0.6 2.6 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 KFM72890.1 - 0.071 14.1 0.4 0.071 14.1 0.4 2.9 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Allexi_40kDa PF05549.11 KFM72890.1 - 1.4 8.4 9.1 0.12 11.9 3.1 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein DDE_Tnp_1_7 PF13843.6 KFM72891.1 - 3.5e-70 237.1 1.0 4.2e-70 236.8 1.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Myb_DNA-bind_4 PF13837.6 KFM72893.1 - 1.6e-15 57.3 0.2 2.3e-15 56.7 0.2 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 KFM72893.1 - 0.0034 18.0 0.2 0.0034 18.0 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF573 Myb_DNA-bind_3 PF12776.7 KFM72893.1 - 0.0036 18.3 0.1 0.0073 17.3 0.0 1.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM72893.1 - 0.034 14.4 0.2 0.055 13.8 0.2 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like EC042_2821 PF18740.1 KFM72893.1 - 0.047 13.6 0.4 0.063 13.2 0.4 1.2 1 0 0 1 1 1 0 EC042_2821-lke REase Myb_DNA-bind_6 PF13921.6 KFM72893.1 - 0.09 13.0 0.1 0.63 10.3 0.1 2.2 1 1 1 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFM72893.1 - 0.097 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain HGTP_anticodon PF03129.20 KFM72893.1 - 0.11 12.6 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Anticodon binding domain Sulfakinin PF08257.11 KFM72895.1 - 0.00047 19.8 4.8 0.0015 18.2 4.8 1.9 1 0 0 1 1 1 1 Sulfakinin family DDE_3 PF13358.6 KFM72897.1 - 1.1e-28 99.8 0.0 5.5e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72897.1 - 4e-25 87.9 7.0 1.1e-15 57.6 2.2 3.3 3 0 0 3 3 3 2 Transposase ACAS_N PF16177.5 KFM72897.1 - 1.9 8.5 7.3 14 5.7 0.8 2.6 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus Trypsin PF00089.26 KFM72898.1 - 2.7e-38 132.0 0.0 3.1e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM72898.1 - 0.00025 22.0 0.4 0.00099 20.0 0.4 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFM72899.1 - 2.3e-16 60.3 0.0 2.5e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 KFM72900.1 - 5e-52 176.9 0.0 5.8e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM72900.1 - 6.9e-05 23.8 0.0 0.00015 22.7 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM72900.1 - 0.0048 17.3 0.0 0.0082 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Bin3 PF06859.12 KFM72901.1 - 2.4e-21 76.4 0.3 4.8e-21 75.4 0.3 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 KFM72901.1 - 2.7e-12 46.8 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM72901.1 - 3.6e-06 27.6 0.0 8.9e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM72901.1 - 1.8e-05 25.3 0.0 3.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM72901.1 - 9.9e-05 22.2 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM72901.1 - 0.00011 22.9 0.1 0.00018 22.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFM72901.1 - 0.00045 20.2 0.0 0.00053 20.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFM72901.1 - 0.02 15.0 0.0 0.026 14.6 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KFM72901.1 - 0.07 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KFM72901.1 - 0.092 12.2 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase zf-Tim10_DDP PF02953.15 KFM72902.1 - 8.3e-23 79.8 1.4 1.2e-22 79.3 1.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger zinc_ribbon_10 PF10058.9 KFM72904.1 - 2.7e-21 75.0 1.5 5.4e-21 74.1 1.5 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF4512 PF14975.6 KFM72904.1 - 2.8 8.8 6.7 0.48 11.2 1.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) RMI2 PF16100.5 KFM72905.1 - 0.0026 17.6 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 AAA_5 PF07728.14 KFM72906.1 - 1.1e-102 339.7 0.1 2.3e-36 124.8 0.0 3.4 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM72906.1 - 1.7e-09 38.3 2.7 0.38 11.1 0.2 5.3 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KFM72906.1 - 2e-06 28.1 2.1 0.035 14.4 0.1 4.6 4 1 0 4 4 4 2 AAA domain Mg_chelatase PF01078.21 KFM72906.1 - 4.8e-06 26.1 0.4 0.18 11.1 0.0 4.3 4 1 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFM72906.1 - 1.2e-05 25.4 0.6 0.098 12.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KFM72906.1 - 1.9e-05 25.1 0.0 0.081 13.4 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 KFM72906.1 - 4.8e-05 23.2 0.2 0.45 10.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KFM72906.1 - 5.5e-05 23.4 0.7 0.27 11.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 KFM72906.1 - 6.2e-05 23.5 0.0 0.96 10.0 0.0 3.9 3 0 0 3 3 3 2 ABC transporter TniB PF05621.11 KFM72906.1 - 0.00058 19.3 0.1 1.7 8.0 0.0 3.4 3 1 1 4 4 4 2 Bacterial TniB protein AAA_7 PF12775.7 KFM72906.1 - 0.00063 19.3 0.0 1.5 8.3 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region CbbQ_C PF08406.10 KFM72906.1 - 0.0008 19.6 0.0 0.26 11.6 0.0 2.8 3 0 0 3 3 2 1 CbbQ/NirQ/NorQ C-terminal Roc PF08477.13 KFM72906.1 - 0.0016 18.7 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFM72906.1 - 0.0034 17.1 0.0 1.2 8.9 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain NACHT PF05729.12 KFM72906.1 - 0.0037 17.2 0.5 0.55 10.1 0.4 3.7 3 1 0 3 3 3 1 NACHT domain DUF262 PF03235.14 KFM72906.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF262 AAA_33 PF13671.6 KFM72906.1 - 0.033 14.4 0.1 3.6 7.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KFM72906.1 - 0.041 13.6 0.6 2.5 7.8 0.0 3.3 3 1 0 3 3 3 0 Sigma-54 interaction domain ATPase PF06745.13 KFM72906.1 - 0.053 12.9 0.0 1.5 8.1 0.0 2.9 3 0 0 3 3 3 0 KaiC VWA PF00092.28 KFM72907.1 - 7.8e-08 32.8 0.0 1.5e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFM72907.1 - 0.00034 21.2 0.0 0.00084 20.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain DASH_Dad1 PF08649.10 KFM72907.1 - 0.57 10.4 2.6 0.83 9.9 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad1 HTH_Tnp_Tc3_2 PF01498.18 KFM72908.1 - 1.8e-16 60.1 2.2 3.7e-16 59.1 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72908.1 - 7.4e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease LRR_8 PF13855.6 KFM72911.1 - 1.4e-109 357.8 168.5 1.4e-15 56.8 6.8 13.6 7 2 7 16 16 16 15 Leucine rich repeat LRR_4 PF12799.7 KFM72911.1 - 6.4e-40 134.5 117.0 3e-05 24.3 2.6 16.3 9 4 6 17 17 17 14 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM72911.1 - 4.3e-35 120.5 16.1 3.2e-09 36.8 0.2 6.7 3 1 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) TIR_2 PF13676.6 KFM72911.1 - 2.5e-16 60.3 0.4 2e-15 57.5 0.2 2.4 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 KFM72911.1 - 1.4e-15 57.5 0.1 2.7e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 KFM72911.1 - 3.2e-14 52.8 54.4 2.5e-05 23.9 2.3 8.8 3 1 7 10 10 10 5 Leucine-rich repeat LRR_1 PF00560.33 KFM72911.1 - 1.6e-08 33.9 102.7 0.13 12.9 1.0 23.1 24 3 0 24 24 24 6 Leucine Rich Repeat DUF1863 PF08937.11 KFM72911.1 - 7e-05 23.1 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) HTH_Tnp_Tc3_2 PF01498.18 KFM72912.1 - 2.4e-16 59.7 2.2 6.4e-16 58.4 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72912.1 - 1.5e-13 50.7 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72912.1 - 3.4e-07 29.9 1.6 7.8e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72912.1 - 0.0031 17.3 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72912.1 - 0.033 14.3 0.4 0.1 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM72912.1 - 3.2 8.4 15.6 0.14 12.8 2.0 3.0 2 1 1 3 3 3 0 Homeodomain-like domain DUF3437 PF11919.8 KFM72913.1 - 0.033 14.1 4.0 4.1 7.4 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) HTH_Tnp_Tc3_2 PF01498.18 KFM72914.1 - 2.1e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72914.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72915.1 - 1.9e-16 60.1 2.2 3.9e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72915.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2 PF00096.26 KFM72916.1 - 3e-26 90.4 62.1 1.4e-05 25.3 0.4 7.8 8 0 0 8 8 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72916.1 - 4.1e-19 67.6 60.9 8.9e-05 23.0 0.2 9.0 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM72916.1 - 1.7e-17 63.0 66.8 2.3e-05 24.6 1.9 10.2 10 2 0 10 10 9 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM72916.1 - 1.2e-11 44.6 39.8 4.4e-05 23.6 0.4 8.6 7 1 1 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM72916.1 - 1.9e-08 34.4 5.6 5.9e-05 23.3 0.2 8.5 9 1 0 9 9 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM72916.1 - 5.4e-06 26.3 56.3 0.038 14.0 0.1 8.5 9 0 0 9 9 8 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM72916.1 - 0.00072 19.4 32.0 0.0035 17.2 1.1 7.3 7 0 0 7 7 7 2 zinc-finger of a C2HC-type FYVE PF01363.21 KFM72916.1 - 0.0032 17.6 36.2 0.011 15.9 3.0 5.7 2 1 2 4 4 4 2 FYVE zinc finger zf-C2H2_9 PF16293.5 KFM72916.1 - 0.0041 16.9 12.9 1.9 8.4 0.2 5.7 4 2 2 6 6 6 1 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KFM72916.1 - 0.016 14.8 0.8 0.016 14.8 0.8 4.9 5 2 2 7 7 6 0 MYST family zinc finger domain DUF3886 PF13025.6 KFM72916.1 - 0.091 13.0 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) zinc_ribbon_9 PF14369.6 KFM72916.1 - 0.093 13.0 20.8 11 6.3 0.2 7.9 9 0 0 9 9 9 0 zinc-ribbon zf-Di19 PF05605.12 KFM72916.1 - 0.23 11.8 34.2 2.4 8.5 1.7 5.5 4 2 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 KFM72916.1 - 0.23 11.5 26.1 0.47 10.5 2.3 6.4 6 1 2 8 8 8 0 Adenylate kinase, active site lid C1_4 PF07975.12 KFM72916.1 - 0.37 11.1 35.9 1.3 9.3 1.4 6.4 2 2 4 7 7 7 0 TFIIH C1-like domain Acetone_carb_G PF08882.11 KFM72916.1 - 0.68 10.1 2.8 1.3 9.1 0.0 2.7 3 0 0 3 3 3 0 Acetone carboxylase gamma subunit zf-Dof PF02701.15 KFM72916.1 - 1 9.5 36.0 0.63 10.2 0.9 7.1 3 3 5 8 8 8 0 Dof domain, zinc finger DUF3741 PF12552.8 KFM72916.1 - 2.7 8.0 4.5 1.3 9.0 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3741) zinc_ribbon_15 PF17032.5 KFM72916.1 - 2.8 8.8 33.9 0.68 10.7 2.0 4.9 2 2 2 5 5 5 0 zinc-ribbon family Ribosomal_S14 PF00253.21 KFM72916.1 - 3.7 7.4 0.0 3.7 7.4 0.0 4.3 5 1 0 5 5 4 0 Ribosomal protein S14p/S29e p450 PF00067.22 KFM72917.1 - 3.7e-08 32.6 0.0 3.9e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM72918.1 - 8.4e-101 338.0 0.0 9.5e-101 337.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M50 PF02163.22 KFM72919.1 - 1.1e-15 57.5 0.0 8e-15 54.8 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 KFM72919.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Dickkopf_N PF04706.12 KFM72919.1 - 1.3 9.5 5.8 2.9 8.4 5.8 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DDE_Tnp_1_7 PF13843.6 KFM72920.1 - 0.0009 18.6 0.0 0.0009 18.6 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Tnp_P_element PF12017.8 KFM72922.1 - 1e-22 80.7 0.0 3.2e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 Transposase protein Tnp_P_element_C PF12596.8 KFM72922.1 - 0.0016 19.0 0.0 0.0033 17.9 0.0 1.6 1 0 0 1 1 1 1 87kDa Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM72923.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72923.1 - 9.4e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DAHP_snth_FXD PF18152.1 KFM72924.1 - 0.012 15.4 0.0 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain DUF918 PF06033.11 KFM72924.1 - 0.019 15.0 0.4 0.022 14.8 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Dopey_N PF04118.14 KFM72925.1 - 1e-63 215.3 0.0 1.1e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Dopey, N-terminal Dopey_N PF04118.14 KFM72926.1 - 4e-07 29.4 0.2 8.2e-07 28.4 0.2 1.6 1 0 0 1 1 1 1 Dopey, N-terminal Pik1 PF11522.8 KFM72926.1 - 0.047 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 7tm_2 PF00002.24 KFM72928.1 - 4e-28 98.4 21.3 5.8e-28 97.8 21.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ocular_alb PF02101.15 KFM72928.1 - 0.01 14.8 0.7 0.01 14.8 0.7 2.6 2 1 0 2 2 2 0 Ocular albinism type 1 protein 7tm_1 PF00001.21 KFM72928.1 - 0.047 13.0 19.4 0.35 10.2 19.4 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1801 PF08818.11 KFM72928.1 - 0.091 13.3 0.1 0.48 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DU1801) HTH_Tnp_Tc3_2 PF01498.18 KFM72929.1 - 4.2e-16 59.0 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72929.1 - 2.5e-13 50.0 0.0 4.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72929.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72929.1 - 0.0026 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72929.1 - 2 9.1 15.6 0.12 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Glyco_transf_22 PF03901.17 KFM72932.1 - 3.1e-15 56.3 5.6 3.4e-15 56.2 5.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_transf_22 PF03901.17 KFM72933.1 - 9.6e-34 117.3 11.4 1.1e-33 117.1 11.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gaa1 PF04114.14 KFM72933.1 - 0.0094 15.0 1.7 0.012 14.6 1.7 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component SLAC1 PF03595.17 KFM72933.1 - 0.03 13.6 4.8 0.23 10.7 4.5 1.8 1 1 0 1 1 1 0 Voltage-dependent anion channel DPM3 PF08285.11 KFM72933.1 - 3.1 8.0 6.4 1.6 9.0 1.4 2.4 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DDE_3 PF13358.6 KFM72936.1 - 0.00063 19.5 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72937.1 - 4.7e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM72937.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM72937.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72937.1 - 0.0025 17.6 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM72937.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-RING_2 PF13639.6 KFM72940.1 - 3.4e-14 52.9 8.7 4.6e-14 52.5 8.7 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFM72940.1 - 1.6e-09 37.3 4.2 2.9e-09 36.5 4.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFM72940.1 - 4.5e-09 36.0 8.7 6.4e-09 35.5 8.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM72940.1 - 6.5e-08 32.7 10.1 2.4e-07 30.9 10.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM72940.1 - 1.5e-07 31.1 8.5 2.4e-07 30.5 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM72940.1 - 1.9e-07 30.9 8.2 2.5e-07 30.5 8.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM72940.1 - 2e-06 27.7 5.8 3.1e-06 27.1 5.8 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFM72940.1 - 6.7e-06 25.9 5.7 9.4e-06 25.4 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFM72940.1 - 0.00036 20.5 4.3 0.0026 17.8 4.3 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFM72940.1 - 0.001 18.9 6.0 0.0018 18.1 6.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KFM72940.1 - 0.0011 18.5 5.3 0.0019 17.8 5.3 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KFM72940.1 - 0.015 15.1 4.8 0.021 14.6 4.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KFM72940.1 - 0.088 13.0 4.7 0.28 11.4 4.8 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KFM72940.1 - 0.088 12.9 7.5 0.22 11.6 7.5 1.8 1 1 0 1 1 1 0 Zinc-finger FYVE_2 PF02318.16 KFM72940.1 - 0.13 12.5 6.2 0.19 12.0 6.2 1.2 1 1 0 1 1 1 0 FYVE-type zinc finger FANCL_C PF11793.8 KFM72940.1 - 0.2 11.9 7.0 0.83 9.9 7.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFM72940.1 - 0.22 11.4 5.1 0.45 10.3 5.1 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KFM72940.1 - 0.25 11.3 9.4 2.6 8.0 9.5 2.1 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.22 KFM72940.1 - 0.38 10.7 9.9 1.6 8.7 5.7 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 KFM72940.1 - 0.8 9.9 7.3 2.9 8.1 7.1 1.9 1 1 1 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 KFM72940.1 - 2.3 8.6 8.7 5.3 7.4 8.4 1.8 1 1 1 2 2 2 0 RING-like domain Myb_DNA-bind_5 PF13873.6 KFM72941.1 - 1e-12 48.0 0.6 2.1e-12 46.9 0.6 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Prokineticin PF06607.11 KFM72942.1 - 6.3e-08 32.8 4.2 8.9e-08 32.4 4.2 1.2 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM72942.1 - 0.0001 22.8 4.7 0.00025 21.6 4.7 1.7 1 0 0 1 1 1 1 MIT-like atracotoxin family Colipase_C PF02740.14 KFM72942.1 - 0.11 12.7 0.8 0.11 12.7 0.8 2.2 3 0 0 3 3 3 0 Colipase, C-terminal domain Prokineticin PF06607.11 KFM72943.1 - 4.9e-06 26.8 9.2 5e-06 26.8 8.7 1.3 1 1 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM72943.1 - 0.00014 22.4 8.5 0.0003 21.3 8.5 1.6 1 1 0 1 1 1 1 MIT-like atracotoxin family Colipase_C PF02740.14 KFM72943.1 - 0.0018 18.4 0.4 0.0018 18.4 0.4 2.0 2 1 0 2 2 2 1 Colipase, C-terminal domain CarbpepA_inh PF02977.15 KFM72943.1 - 0.012 15.4 7.7 0.015 15.0 4.9 2.4 2 2 0 2 2 2 0 Carboxypeptidase A inhibitor DUF659 PF04937.15 KFM72944.1 - 6.6e-05 22.8 0.2 0.00022 21.1 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM72944.1 - 0.00043 20.0 0.4 0.0015 18.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) DDE_3 PF13358.6 KFM72945.1 - 0.00092 19.0 0.0 0.00099 18.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM72946.1 - 1.9e-09 37.5 0.3 3.9e-09 36.5 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM72946.1 - 0.0019 17.8 0.2 0.0043 16.6 0.1 1.7 1 1 0 1 1 1 1 Zinc-finger C2H2-type GAGA PF09237.11 KFM72946.1 - 0.098 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 GAGA factor TIG_2 PF18020.1 KFM72948.1 - 0.048 14.3 0.0 0.062 13.9 0.0 1.1 1 0 0 1 1 1 0 TIG domain found in plexin DUF4817 PF16087.5 KFM72950.1 - 5.9e-07 29.2 0.0 2.2e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) HTH_Tnp_Tc3_2 PF01498.18 KFM72950.1 - 1.1e-06 28.7 0.2 2.4e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM72950.1 - 0.002 18.7 0.9 0.002 18.7 0.9 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 KFM72950.1 - 0.02 14.4 0.2 0.037 13.6 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 KFM72950.1 - 0.05 13.2 1.5 0.078 12.6 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM72950.1 - 0.06 12.8 0.6 0.16 11.4 0.6 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_6 PF01418.17 KFM72950.1 - 0.19 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family TPR_1 PF00515.28 KFM72951.1 - 5.9e-22 76.5 49.1 8.3e-06 25.4 0.0 10.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFM72951.1 - 4e-21 73.4 32.1 0.00079 19.5 0.0 11.3 10 1 0 10 10 10 5 Tetratricopeptide repeat ANAPC8 PF04049.13 KFM72951.1 - 1.5e-18 67.2 11.5 1.8e-18 67.0 4.5 3.0 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.17 KFM72951.1 - 5.3e-18 63.6 47.0 0.00042 20.2 0.0 10.9 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFM72951.1 - 4.2e-11 42.7 23.5 0.073 13.9 0.0 8.9 8 2 2 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFM72951.1 - 1.5e-09 37.6 21.9 0.33 11.4 0.0 9.0 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM72951.1 - 2.9e-09 36.5 19.2 3.3e-06 26.7 0.1 6.1 5 1 1 6 6 6 2 TPR repeat TPR_19 PF14559.6 KFM72951.1 - 4e-09 36.9 20.6 0.24 11.9 0.3 8.5 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFM72951.1 - 2.6e-08 33.3 16.0 0.8 9.9 0.0 9.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM72951.1 - 5.8e-07 29.7 32.1 1.9 9.3 0.0 10.3 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM72951.1 - 5e-06 27.1 24.8 0.0023 18.5 0.0 8.0 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM72951.1 - 7.6e-05 22.8 3.2 0.4 10.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM72951.1 - 0.00098 18.6 3.6 0.0017 17.8 1.3 2.3 3 0 0 3 3 3 1 MalT-like TPR region TPR_12 PF13424.6 KFM72951.1 - 0.0014 18.9 36.4 0.047 14.0 0.2 7.6 6 3 4 10 10 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM72951.1 - 0.021 15.0 34.8 0.39 11.0 3.2 6.2 5 2 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 ORC2 PF04084.14 KFM72951.1 - 0.029 13.3 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 2 TPR_10 PF13374.6 KFM72951.1 - 0.71 9.8 18.0 9.7 6.2 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 KFM72951.1 - 3.6 7.3 20.0 7.5 6.2 5.0 4.4 3 2 0 4 4 4 0 26S proteasome subunit RPN7 DUF4508 PF14969.6 KFM72952.1 - 8.9e-22 77.2 4.6 9.9e-22 77.0 4.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) UBA PF00627.31 KFM72953.1 - 3e-09 36.6 0.0 3.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 UBA/TS-N domain LRR_8 PF13855.6 KFM72957.1 - 1.4e-13 50.4 0.6 1.2e-06 28.2 0.0 4.0 2 1 2 4 4 4 2 Leucine rich repeat LRR_5 PF13306.6 KFM72957.1 - 0.0047 16.9 0.0 0.043 13.8 0.0 2.2 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM72957.1 - 0.02 14.4 0.2 0.04 13.4 0.0 1.5 2 0 0 2 2 2 0 Leucine-rich repeat LRR_4 PF12799.7 KFM72957.1 - 0.26 11.8 0.1 0.26 11.8 0.1 3.1 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) HTH_Tnp_Tc3_2 PF01498.18 KFM72958.1 - 2.1e-16 59.9 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72958.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_2 PF00002.24 KFM72959.1 - 1.2e-40 139.4 17.2 1.8e-40 138.8 17.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFM72959.1 - 6.9e-35 120.4 0.0 9.9e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.18 KFM72959.1 - 4e-19 68.8 0.6 1.3e-18 67.2 0.6 2.0 1 0 0 1 1 1 1 Galactose binding lectin domain GPS PF01825.21 KFM72959.1 - 2e-13 50.6 7.6 4.8e-13 49.4 7.6 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFM72959.1 - 0.0051 17.1 2.7 0.0051 17.1 2.7 3.0 2 0 0 2 2 2 1 Hormone receptor domain Tape_meas_lam_C PF09718.10 KFM72959.1 - 0.049 13.8 0.1 2.7 8.2 0.0 2.6 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF4371 PF14291.6 KFM72960.1 - 4e-10 39.8 0.1 1.3e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM72960.1 - 0.0029 17.1 0.8 0.0029 17.1 0.8 2.3 2 1 0 2 2 2 1 Zinc-finger C2H2-type DNA_pol3_beta PF00712.19 KFM72960.1 - 0.18 11.9 1.7 0.27 11.4 0.3 2.0 2 0 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain Acyltransferase PF01553.21 KFM72961.1 - 0.00031 20.4 0.1 0.00081 19.0 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase DUF3992 PF13157.6 KFM72961.1 - 0.11 13.2 0.1 0.16 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) TUDOR PF00567.24 KFM72963.1 - 4.2e-83 275.4 16.3 2.4e-22 79.2 0.0 5.3 5 0 0 5 5 5 5 Tudor domain DUF4537 PF15057.6 KFM72963.1 - 4.5e-08 33.1 0.6 0.92 9.5 0.0 4.8 4 0 0 4 4 4 4 Domain of unknown function (DUF4537) SMN PF06003.12 KFM72963.1 - 0.00018 20.8 0.2 0.041 13.2 0.0 3.0 3 0 0 3 3 3 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KFM72963.1 - 0.00048 20.5 3.5 36 4.9 0.0 4.9 4 0 0 4 4 4 0 Agenet domain Tudor_2 PF18104.1 KFM72963.1 - 0.02 14.6 7.1 6.6 6.5 0.2 4.2 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain Tudor-knot PF11717.8 KFM72963.1 - 0.089 12.7 0.3 75 3.3 0.0 3.8 4 0 0 4 4 4 0 RNA binding activity-knot of a chromodomain TUDOR PF00567.24 KFM72964.1 - 1.7e-34 118.5 0.9 6.4e-23 81.1 0.0 2.4 2 0 0 2 2 2 2 Tudor domain Agenet PF05641.12 KFM72964.1 - 3.5e-06 27.4 0.1 0.093 13.2 0.0 2.6 2 0 0 2 2 2 2 Agenet domain DUF4537 PF15057.6 KFM72964.1 - 0.0042 17.1 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) TUDOR PF00567.24 KFM72965.1 - 5.4e-10 39.4 0.4 2e-09 37.5 0.4 2.1 1 0 0 1 1 1 1 Tudor domain RRM_1 PF00076.22 KFM72965.1 - 1.7e-07 30.9 0.1 6.2e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-MYND PF01753.18 KFM72965.1 - 1e-05 25.5 10.2 1e-05 25.5 10.2 2.1 2 0 0 2 2 2 1 MYND finger YtxH PF12732.7 KFM72966.1 - 8.8e-06 26.2 20.3 0.12 13.0 1.3 5.4 1 1 1 2 2 2 1 YtxH-like protein PSK_trans_fac PF07704.11 KFM72966.1 - 3.3e-05 24.5 2.7 0.00034 21.3 2.7 2.7 1 1 0 1 1 1 1 Rv0623-like transcription factor RHD3 PF05879.12 KFM72966.1 - 6.9e-05 21.2 5.1 6.9e-05 21.2 5.1 2.0 1 1 1 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) Apolipoprotein PF01442.18 KFM72966.1 - 0.00013 21.9 9.6 0.01 15.7 9.6 2.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KFM72966.1 - 0.00056 20.5 9.0 0.018 15.6 1.7 4.3 2 2 2 4 4 4 1 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 KFM72966.1 - 0.00065 19.8 14.4 0.0099 16.0 1.7 3.9 1 1 2 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 KFM72966.1 - 0.0017 16.5 6.2 0.0023 16.0 6.2 1.3 1 0 0 1 1 1 1 Prominin Spore_III_AB PF09548.10 KFM72966.1 - 0.0049 17.0 16.4 0.0095 16.1 8.7 2.6 1 1 1 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) Death PF00531.22 KFM72966.1 - 0.0049 17.0 3.9 4.1 7.6 0.6 3.6 1 1 2 3 3 3 0 Death domain DUF1805 PF08827.11 KFM72966.1 - 0.011 16.1 0.4 0.097 13.0 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1805) Snapin_Pallidin PF14712.6 KFM72966.1 - 0.022 15.2 3.2 0.022 15.2 3.2 3.6 1 1 0 2 2 2 0 Snapin/Pallidin Fe_dep_repr_C PF02742.15 KFM72966.1 - 0.024 14.7 4.0 1 9.5 0.1 3.8 1 1 2 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain OmpH PF03938.14 KFM72966.1 - 0.025 14.9 16.9 0.23 11.8 6.2 3.1 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) LEA_4 PF02987.16 KFM72966.1 - 0.034 14.2 5.9 1.1 9.4 0.3 3.4 3 1 0 3 3 2 0 Late embryogenesis abundant protein SseC PF04888.12 KFM72966.1 - 0.049 13.2 4.7 0.1 12.2 1.2 2.8 1 1 0 2 2 2 0 Secretion system effector C (SseC) like family TMP PF05017.14 KFM72966.1 - 0.062 13.9 1.6 0.56 11.0 0.2 3.4 2 0 0 2 2 1 0 TMP repeat Herpes_UL6 PF01763.16 KFM72966.1 - 0.069 11.7 6.8 0.028 12.9 1.3 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF2884 PF11101.8 KFM72966.1 - 0.093 12.2 11.5 0.014 15.0 4.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2884) DUF885 PF05960.11 KFM72966.1 - 0.17 11.5 2.2 0.27 10.8 1.5 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Ku_PK_bind PF08785.11 KFM72966.1 - 0.21 11.8 10.8 0.7 10.1 0.4 3.3 2 1 0 2 2 2 0 Ku C terminal domain like DUF3502 PF12010.8 KFM72966.1 - 0.26 11.9 7.7 3 8.5 0.3 3.1 2 2 1 3 3 2 0 Domain of unknown function (DUF3502) LEA_1 PF03760.15 KFM72966.1 - 0.34 11.6 3.3 14 6.5 0.2 2.8 1 1 1 2 2 2 0 Late embryogenesis abundant (LEA) group 1 COG5 PF10392.9 KFM72966.1 - 0.38 10.9 7.0 3.4 7.9 0.4 2.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 7TMR-HDED PF07697.11 KFM72966.1 - 0.42 10.7 9.4 1.7 8.8 9.4 2.1 1 1 0 1 1 1 0 7TM-HD extracellular F_actin_bind PF08919.10 KFM72966.1 - 0.46 10.6 3.9 6.1 7.0 2.2 2.9 1 1 2 3 3 3 0 F-actin binding Peptidase_M41 PF01434.18 KFM72966.1 - 0.52 10.1 12.3 0.17 11.7 0.9 3.4 1 1 3 4 4 4 0 Peptidase family M41 DUF4145 PF13643.6 KFM72966.1 - 0.53 10.4 10.9 2.6 8.2 0.8 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4145) DnaI_N PF07319.11 KFM72966.1 - 0.54 11.0 14.3 0.22 12.2 1.7 4.0 2 1 2 4 4 4 0 Primosomal protein DnaI N-terminus VEG PF06257.11 KFM72966.1 - 0.55 10.3 11.1 0.35 10.9 0.2 4.0 3 1 2 5 5 4 0 Biofilm formation stimulator VEG DUF1664 PF07889.12 KFM72966.1 - 0.7 9.9 16.3 0.2 11.7 3.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CRR7 PF12095.8 KFM72966.1 - 0.72 10.3 5.6 1.8 9.1 0.1 3.4 2 1 2 4 4 3 0 Protein CHLORORESPIRATORY REDUCTION 7 PIN_8 PF18476.1 KFM72966.1 - 0.79 9.5 15.5 0.17 11.7 8.1 2.5 1 1 1 3 3 3 0 PIN like domain DUF1690 PF07956.11 KFM72966.1 - 0.84 10.1 18.2 0.26 11.7 5.8 3.2 1 1 1 3 3 3 0 Protein of Unknown function (DUF1690) DUF1771 PF08590.10 KFM72966.1 - 1.5 9.3 3.8 42 4.6 0.2 3.3 4 0 0 4 4 2 0 Domain of unknown function (DUF1771) Exonuc_VII_L PF02601.15 KFM72966.1 - 1.5 8.3 10.3 1.7 8.1 9.1 1.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF2203 PF09969.9 KFM72966.1 - 1.9 9.3 11.0 0.88 10.3 3.4 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) MnmE_helical PF12631.7 KFM72966.1 - 2.1 8.5 14.3 1.4 9.0 12.0 2.0 1 1 1 2 2 2 0 MnmE helical domain DYW_deaminase PF14432.6 KFM72966.1 - 2.4 8.0 4.7 6 6.8 0.7 2.6 1 1 0 2 2 2 0 DYW family of nucleic acid deaminases Glyoxalase_2 PF12681.7 KFM72966.1 - 2.5 8.1 10.2 31 4.5 0.4 3.9 1 1 4 5 5 5 0 Glyoxalase-like domain DcpS_C PF11969.8 KFM72966.1 - 3 8.3 7.4 34 5.0 0.0 3.8 2 1 1 4 4 4 0 Scavenger mRNA decapping enzyme C-term binding Phasin PF05597.11 KFM72966.1 - 3.1 7.8 11.0 3.7 7.6 4.1 3.5 1 1 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) IlvC PF01450.19 KFM72966.1 - 3.2 8.0 10.0 0.37 11.1 1.2 3.0 1 1 1 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF4404 PF14357.6 KFM72966.1 - 3.3 8.4 9.0 12 6.6 3.1 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) PIN_12 PF16289.5 KFM72966.1 - 4.2 7.8 21.4 3.2 8.2 4.3 3.2 1 1 2 3 3 3 0 PIN domain EnY2 PF10163.9 KFM72966.1 - 5.1 7.6 12.8 3.4 8.1 1.7 4.0 1 1 2 3 3 3 0 Transcription factor e(y)2 PurS PF02700.14 KFM72966.1 - 5.7 7.2 8.2 4.9 7.4 0.6 3.6 2 1 2 4 4 3 0 Phosphoribosylformylglycinamidine (FGAM) synthase YojJ PF10372.9 KFM72966.1 - 6.1 7.0 12.6 6.9 6.8 0.5 4.4 3 2 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus RecG_N PF17190.4 KFM72966.1 - 7.3 7.4 21.1 1.1 10.0 3.1 3.9 1 1 2 3 3 3 0 RecG N-terminal helical domain NPA PF16469.5 KFM72966.1 - 8.3 7.0 22.0 8.6 7.0 9.6 3.9 2 1 2 4 4 4 0 Nematode polyprotein allergen ABA-1 LIN52 PF10044.9 KFM72966.1 - 8.4 7.2 10.2 12 6.7 0.3 3.4 2 1 2 4 4 3 0 Retinal tissue protein Sld5 PF05916.11 KFM72966.1 - 8.5 6.9 10.7 97 3.5 4.3 3.4 1 1 1 2 2 2 0 GINS complex protein CDC37_N PF03234.14 KFM72966.1 - 8.6 7.3 13.0 5 8.1 4.7 3.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Spore_II_R PF09551.10 KFM72966.1 - 9.7 6.7 10.1 5.4 7.5 1.9 3.2 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) A_deaminase PF00962.22 KFM72967.1 - 7.7e-68 229.2 0.0 8.9e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Chitin_bind_4 PF00379.23 KFM72968.1 - 1.3e-11 44.9 2.3 1.8e-11 44.4 2.3 1.3 1 0 0 1 1 1 1 Insect cuticle protein BAMBI PF06211.12 KFM72970.1 - 0.005 17.1 0.9 0.014 15.7 0.9 1.8 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Activin_recp PF01064.23 KFM72970.1 - 0.1 13.7 2.9 0.1 13.7 1.8 1.6 2 0 0 2 2 2 0 Activin types I and II receptor domain HemY_N PF07219.13 KFM72970.1 - 0.12 12.6 1.0 0.18 12.0 1.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus zf-H2C2_2 PF13465.6 KFM72971.1 - 7.4e-52 171.6 67.4 1e-07 32.0 0.3 10.1 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72971.1 - 8.8e-36 120.4 87.0 4.8e-06 26.7 4.8 9.9 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72971.1 - 5.2e-28 95.3 81.2 0.00059 20.5 3.4 10.0 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFM72971.1 - 1.1e-17 63.8 64.0 0.023 15.1 2.9 10.2 10 0 0 10 10 10 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM72971.1 - 6.4e-09 35.9 52.5 0.17 12.2 1.2 9.7 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM72971.1 - 1.2e-05 25.0 37.1 0.96 9.3 0.1 9.2 2 1 8 10 10 9 2 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM72971.1 - 2.9e-05 24.1 39.5 2.2 8.5 1.2 8.7 9 0 0 9 9 8 1 DBF zinc finger zf-C2H2_6 PF13912.6 KFM72971.1 - 3.5e-05 23.7 63.6 0.2 11.7 1.4 8.6 8 0 0 8 8 8 4 C2H2-type zinc finger AMP_N PF05195.16 KFM72971.1 - 0.00043 20.0 0.0 0.28 10.9 0.0 3.0 2 1 0 3 3 3 1 Aminopeptidase P, N-terminal domain DUF2757 PF10955.8 KFM72971.1 - 0.00049 20.3 31.1 3.4 8.0 0.2 8.1 8 1 0 8 8 8 2 Protein of unknown function (DUF2757) zf-Sec23_Sec24 PF04810.15 KFM72971.1 - 0.0031 17.5 29.8 2 8.5 0.2 8.0 6 2 2 8 8 8 2 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM72971.1 - 0.008 16.3 34.5 1.2 9.3 5.0 4.3 1 1 3 4 4 4 2 Putative ribonucleoprotein zinc-finger pf C4 type GAGA PF09237.11 KFM72971.1 - 0.0081 16.0 30.6 1.7 8.5 0.1 8.1 1 1 8 9 9 9 2 GAGA factor ADK_lid PF05191.14 KFM72971.1 - 0.013 15.5 33.7 1.4 9.0 1.2 5.5 4 2 1 5 5 5 0 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM72971.1 - 0.034 14.1 32.0 3.6 7.6 0.2 8.0 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM72971.1 - 0.07 12.7 37.5 1.8 8.2 0.3 7.9 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 KFM72971.1 - 0.12 12.3 31.1 14 5.7 2.1 7.8 6 2 0 6 6 6 0 Prokaryotic RING finger family 1 NAD_kinase PF01513.21 KFM72971.1 - 0.12 11.5 0.5 16 4.5 0.1 2.8 1 1 0 2 2 2 0 ATP-NAD kinase DUF2256 PF10013.9 KFM72971.1 - 0.16 12.1 32.6 9.4 6.5 0.1 8.3 9 0 0 9 9 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Suppressor_P21 PF11479.8 KFM72971.1 - 0.24 11.6 2.2 18 5.6 0.0 3.5 3 1 1 4 4 3 0 RNA silencing suppressor P21 C-terminal domain zinc_ribbon_15 PF17032.5 KFM72971.1 - 0.26 12.1 33.2 3.1 8.6 3.7 4.7 1 1 2 4 4 4 0 zinc-ribbon family PqqA PF08042.11 KFM72971.1 - 0.28 11.3 5.9 2.2e+02 2.1 0.0 5.9 7 0 0 7 7 7 0 PqqA family zf-CHCC PF10276.9 KFM72971.1 - 0.29 11.2 17.1 25 5.0 0.0 6.9 8 0 0 8 8 7 0 Zinc-finger domain K_oxygenase PF13434.6 KFM72971.1 - 0.45 9.6 4.0 7.6 5.6 0.1 3.5 1 1 3 5 5 5 0 L-lysine 6-monooxygenase (NADPH-requiring) Zn-ribbon_8 PF09723.10 KFM72971.1 - 0.76 9.9 32.7 2.3 8.4 2.1 5.5 3 2 3 6 6 6 0 Zinc ribbon domain zf-MYST PF17772.1 KFM72971.1 - 0.99 9.1 46.3 1.2 8.8 0.3 8.3 4 4 4 8 8 8 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 KFM72971.1 - 2.8 8.3 61.3 16 5.9 0.8 8.3 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.6 KFM72971.1 - 4.3 7.3 32.2 27 4.7 0.1 7.6 6 3 0 6 6 6 0 HNH endonuclease FYVE PF01363.21 KFM72971.1 - 6.5 7.0 44.4 7.5 6.8 17.0 5.0 1 1 4 5 5 5 0 FYVE zinc finger Scramblase PF03803.15 KFM72971.1 - 6.9 5.9 7.7 9.2 5.5 0.9 2.7 1 1 2 3 3 3 0 Scramblase zf-H2C2_2 PF13465.6 KFM72972.1 - 3.7e-41 137.8 36.3 1.5e-08 34.7 1.0 6.1 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM72972.1 - 4.4e-26 89.8 46.3 3.2e-06 27.3 1.3 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM72972.1 - 2.1e-19 68.5 45.3 0.00025 21.6 1.4 5.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM72972.1 - 1.9e-18 66.2 38.5 0.00011 22.4 1.6 5.2 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM72972.1 - 4.9e-11 42.3 42.3 0.022 14.7 2.7 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM72972.1 - 5.6e-09 35.9 11.0 0.23 11.5 0.1 5.1 3 1 2 5 5 5 3 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KFM72972.1 - 1.6e-08 34.6 28.6 0.15 12.4 0.2 5.7 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 KFM72972.1 - 1.1e-06 28.6 15.0 3.7 7.8 0.5 5.3 5 0 0 5 5 5 2 DBF zinc finger zf_UBZ PF18439.1 KFM72972.1 - 2.5e-06 27.0 22.7 0.6 9.8 0.1 5.1 5 0 0 5 5 5 4 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KFM72972.1 - 1.2e-05 25.0 21.2 1.9 8.4 0.4 5.0 2 2 3 5 5 5 4 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KFM72972.1 - 2.1e-05 24.0 20.2 0.43 10.2 0.2 5.0 2 1 3 5 5 5 2 MYST family zinc finger domain DUF2256 PF10013.9 KFM72972.1 - 0.00023 21.2 15.9 1.7 8.8 0.2 5.1 5 0 0 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2256) TRAF6_Z2 PF18048.1 KFM72972.1 - 0.00024 21.1 17.8 2.4 8.3 0.7 5.3 5 0 0 5 5 5 2 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_2 PF12756.7 KFM72972.1 - 0.00036 20.8 33.3 0.88 9.9 0.8 5.0 1 1 4 5 5 5 4 C2H2 type zinc-finger (2 copies) DUF2757 PF10955.8 KFM72972.1 - 0.00057 20.1 11.0 11 6.3 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2757) zf-C2H2_11 PF16622.5 KFM72972.1 - 0.0011 18.6 38.7 0.19 11.5 1.8 5.1 5 0 0 5 5 5 4 zinc-finger C2H2-type GAGA PF09237.11 KFM72972.1 - 0.0013 18.5 8.0 2 8.3 0.0 4.6 1 1 4 5 5 5 1 GAGA factor BolA PF01722.18 KFM72972.1 - 0.0021 18.3 7.3 1.5 9.2 0.5 3.5 1 1 3 4 4 4 1 BolA-like protein zf-RRPl_C4 PF17026.5 KFM72972.1 - 0.0023 18.0 18.3 0.055 13.6 3.1 2.7 1 1 1 2 2 2 2 Putative ribonucleoprotein zinc-finger pf C4 type zf-BED PF02892.15 KFM72972.1 - 0.0032 17.4 32.0 2 8.5 1.3 5.1 1 1 4 5 5 5 2 BED zinc finger Zf_RING PF16744.5 KFM72972.1 - 0.0061 16.7 19.4 10 6.3 3.8 4.9 1 1 3 4 4 4 0 KIAA1045 RING finger C1_1 PF00130.22 KFM72972.1 - 0.0063 16.4 28.7 0.83 9.6 6.8 4.5 2 1 2 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 KFM72972.1 - 0.0066 16.3 20.7 2.4 8.1 1.3 5.0 5 0 0 5 5 5 1 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM72972.1 - 0.01 15.8 15.2 0.25 11.4 3.3 3.5 2 2 2 4 4 4 0 Adenylate kinase, active site lid zf-C2H2_3rep PF18868.1 KFM72972.1 - 0.012 16.3 12.6 13 6.5 0.4 4.8 3 2 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats Fe_hyd_SSU PF02256.17 KFM72972.1 - 0.023 14.8 15.6 0.89 9.7 0.7 4.6 3 2 2 5 5 5 0 Iron hydrogenase small subunit Prok-RING_1 PF14446.6 KFM72972.1 - 0.074 13.0 17.3 21 5.1 3.4 4.9 4 1 0 4 4 4 0 Prokaryotic RING finger family 1 TRPM_tetra PF16519.5 KFM72972.1 - 0.081 13.0 1.6 60 3.8 0.1 3.8 4 0 0 4 4 4 0 Tetramerisation domain of TRPM FYVE PF01363.21 KFM72972.1 - 0.11 12.7 26.4 18 5.6 13.8 3.1 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_UBOX PF13445.6 KFM72972.1 - 0.11 12.6 12.6 38 4.4 0.3 5.0 5 0 0 5 5 5 0 RING-type zinc-finger DUF5330 PF17264.2 KFM72972.1 - 0.14 12.1 9.1 25 5.0 0.0 4.8 5 0 0 5 5 5 0 Family of unknown function (DUF5330) PqqA PF08042.11 KFM72972.1 - 0.25 11.4 2.8 31 4.8 0.0 3.8 4 0 0 4 4 4 0 PqqA family Cas_CXXC_CXXC PF09706.10 KFM72972.1 - 0.36 11.1 14.4 17 5.7 1.3 4.7 1 1 4 5 5 5 0 CRISPR-associated protein (Cas_CXXC_CXXC) zinc_ribbon_15 PF17032.5 KFM72972.1 - 0.46 11.3 19.0 56 4.6 9.9 3.0 1 1 1 2 2 2 0 zinc-ribbon family HNH PF01844.23 KFM72972.1 - 0.73 10.0 18.9 21 5.4 0.2 5.1 5 0 0 5 5 5 0 HNH endonuclease FYDLN_acid PF09538.10 KFM72972.1 - 0.93 10.2 10.5 20 5.9 1.0 4.2 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) zf-HIT PF04438.16 KFM72972.1 - 0.94 9.4 23.7 11 6.0 0.4 5.2 5 0 0 5 5 5 0 HIT zinc finger C1_4 PF07975.12 KFM72972.1 - 1.1 9.5 21.9 3 8.2 4.9 3.3 2 1 0 3 3 3 0 TFIIH C1-like domain Sgf11 PF08209.11 KFM72972.1 - 1.3 8.6 16.5 22 4.7 0.2 5.1 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) Ribosomal_L35p PF01632.19 KFM72972.1 - 1.9 9.1 9.2 18 5.9 0.1 4.0 3 2 1 4 4 4 0 Ribosomal protein L35 OTU PF02338.19 KFM72973.1 - 0.0011 19.4 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Med12 PF09497.10 KFM72974.1 - 4.4e-17 62.1 0.2 8.7e-17 61.2 0.2 1.5 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 HTH_7 PF02796.15 KFM72975.1 - 1.6e-07 31.3 0.4 0.00034 20.6 0.0 2.6 2 1 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM72975.1 - 1.5e-06 28.7 2.3 2e-06 28.3 2.2 1.2 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM72975.1 - 9.7e-06 25.6 0.7 6.4e-05 23.0 0.0 2.2 1 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72975.1 - 1.6e-05 24.5 3.1 0.00024 20.8 0.0 2.4 3 0 0 3 3 3 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM72975.1 - 0.00026 20.5 0.2 0.0013 18.3 0.0 2.0 2 1 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR_2 PF12802.7 KFM72975.1 - 0.0013 18.5 0.1 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 KFM72975.1 - 0.0018 18.0 0.0 0.0054 16.5 0.0 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM72975.1 - 0.0026 18.0 2.7 0.014 15.6 1.1 2.1 2 0 0 2 2 2 1 Transposase Sigma70_r4 PF04545.16 KFM72975.1 - 0.003 17.0 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Sigma-70, region 4 Tox-REase-7 PF15649.6 KFM72975.1 - 0.0073 16.6 0.0 0.0078 16.5 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 7 HTH_38 PF13936.6 KFM72975.1 - 0.02 14.6 0.4 0.074 12.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM72975.1 - 0.045 13.8 0.2 0.11 12.5 0.1 1.8 1 1 0 1 1 1 0 Winged helix-turn helix TrmB PF01978.19 KFM72975.1 - 0.063 13.2 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 KFM72975.1 - 0.067 13.1 0.7 0.18 11.7 0.0 2.0 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family HTH_6 PF01418.17 KFM72975.1 - 0.068 13.2 0.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family CRAL_TRIO PF00650.20 KFM72976.1 - 7.2e-28 97.3 0.0 1.3e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM72976.1 - 6e-09 36.5 0.7 5.7e-06 26.9 0.0 2.6 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.6 KFM72976.1 - 0.0023 18.1 0.0 0.0054 16.9 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM72976.1 - 0.011 15.9 0.2 0.031 14.4 0.2 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 KFM72977.1 - 2.9e-31 108.3 0.1 4.8e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM72977.1 - 9e-12 45.7 0.0 0.00015 22.3 0.0 2.4 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 KFM72977.1 - 1.4e-06 28.3 0.7 3e-06 27.3 0.7 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM72977.1 - 0.0012 19.0 0.5 0.0022 18.2 0.1 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain C1q PF00386.21 KFM72977.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 C1q domain Ku_PK_bind PF08785.11 KFM72977.1 - 0.28 11.4 2.2 0.86 9.8 0.7 2.1 2 0 0 2 2 2 0 Ku C terminal domain like TF_AP-2 PF03299.14 KFM72977.1 - 0.3 11.0 1.6 0.51 10.3 0.1 1.9 2 0 0 2 2 2 0 Transcription factor AP-2 DDE_3 PF13358.6 KFM72979.1 - 2e-16 60.0 0.0 5.7e-13 48.9 0.0 2.7 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72979.1 - 3.9e-16 59.1 2.2 1.1e-15 57.6 2.2 1.9 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 KFM72979.1 - 6.9e-07 28.9 1.6 1.3e-06 28.1 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM72979.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.3 2 0 0 2 2 2 0 Homeodomain-like domain UL41A PF17591.2 KFM72979.1 - 0.14 12.3 0.7 0.29 11.3 0.7 1.5 1 0 0 1 1 1 0 Herpesvirus UL41A DUF2207 PF09972.9 KFM72979.1 - 0.26 10.0 0.4 0.45 9.2 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PRE_C2HC PF07530.11 KFM72980.1 - 0.00041 20.4 0.3 0.0007 19.7 0.3 1.4 1 0 0 1 1 1 1 Associated with zinc fingers Pkinase PF00069.25 KFM72981.1 - 1.1e-41 142.9 5.4 3.2e-22 79.2 0.2 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM72981.1 - 2.8e-11 43.2 0.1 1.3e-09 37.8 0.1 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM72981.1 - 0.0015 17.4 1.5 0.002 17.0 0.9 1.5 1 1 0 1 1 1 1 Fungal protein kinase DUF382 PF04037.13 KFM72981.1 - 0.056 13.6 1.9 0.12 12.6 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF382) RIO1 PF01163.22 KFM72981.1 - 1.4 8.5 4.4 0.2 11.2 0.1 1.7 2 0 0 2 2 2 0 RIO1 family Tubulin PF00091.25 KFM72982.1 - 1.7e-52 178.5 0.0 2e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFM72982.1 - 0.00012 21.8 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.17 KFM72983.1 - 4.6e-35 120.5 0.0 6e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain PDZ PF00595.24 KFM72984.1 - 3.9e-68 225.8 9.6 7e-19 68.0 0.5 4.7 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFM72984.1 - 6.2e-38 128.4 0.7 3.1e-12 46.1 0.0 4.5 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFM72984.1 - 2.5e-27 95.0 3.3 9.7e-10 38.6 0.3 4.9 4 0 0 4 4 4 4 PDZ domain PDZ_4 PF17816.1 KFM72984.1 - 0.00015 22.1 0.8 4.5 7.7 0.0 4.3 4 1 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 KFM72984.1 - 0.00053 19.9 1.6 1.7 8.7 0.1 4.4 4 0 0 4 4 4 1 Tricorn protease PDZ domain DNA_pol_alpha_N PF12254.8 KFM72984.1 - 0.52 10.4 2.7 1.6 8.8 2.7 1.9 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal DDE_3 PF13358.6 KFM72986.1 - 2e-12 47.1 0.1 2.4e-11 43.6 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72986.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM72987.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72987.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM72988.1 - 2.1e-16 59.9 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM72988.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-RING_2 PF13639.6 KFM72989.1 - 1.4e-11 44.5 5.9 1.4e-11 44.5 5.9 1.5 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KFM72989.1 - 5.2e-11 42.1 5.0 5.2e-11 42.1 5.0 2.0 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFM72989.1 - 4.5e-08 32.8 5.9 7.1e-08 32.2 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM72989.1 - 1.1e-07 31.8 3.0 2.8e-07 30.4 3.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM72989.1 - 3.1e-07 30.2 3.9 5.5e-07 29.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM72989.1 - 2.1e-06 27.5 2.2 3.3e-06 26.8 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM72989.1 - 3.2e-06 27.3 7.5 1.5e-05 25.2 7.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM72989.1 - 2.2e-05 24.3 2.8 3.3e-05 23.8 2.2 1.6 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM72989.1 - 0.00012 21.9 2.0 0.00022 21.0 2.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KFM72989.1 - 0.00062 19.3 4.3 0.0012 18.4 4.3 1.5 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KFM72989.1 - 0.031 14.3 4.1 0.073 13.1 4.1 1.7 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KFM72989.1 - 0.065 13.4 7.3 1.3 9.2 7.3 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.6 KFM72989.1 - 0.086 12.7 1.6 0.16 11.9 1.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KFM72989.1 - 0.15 12.3 3.0 0.38 11.0 3.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFM72989.1 - 0.25 11.4 6.1 4.2 7.5 6.5 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 KFM72989.1 - 1.4 9.3 4.4 2.5 8.5 4.0 1.7 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.7 KFM72989.1 - 1.6 8.9 5.2 6.9 6.9 5.0 2.0 1 1 1 2 2 2 0 RING-variant domain ANAPC4_WD40 PF12894.7 KFM72991.1 - 0.16 12.3 0.0 0.92 9.9 0.0 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4482 PF14818.6 KFM72992.1 - 0.025 15.4 12.4 0.66 10.8 3.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) Cwf_Cwc_15 PF04889.12 KFM72992.1 - 0.44 10.2 10.9 0.95 9.1 10.9 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HPPK PF01288.20 KFM72993.1 - 0.13 12.8 0.1 0.44 11.1 0.0 2.0 2 0 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) APG6_N PF17675.1 KFM72993.1 - 0.17 12.4 5.4 1.2 9.7 5.4 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region IRF-2BP1_2 PF11261.8 KFM72994.1 - 2.2e-30 104.0 0.9 2.2e-30 104.0 0.9 1.8 2 0 0 2 2 2 1 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4 PF00097.25 KFM72994.1 - 1.7e-05 24.6 4.5 1.7e-05 24.6 4.5 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM72994.1 - 0.012 15.5 5.0 0.012 15.5 5.0 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM72994.1 - 0.016 15.0 7.7 0.061 13.2 7.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cobalamin_bind PF01122.19 KFM72995.1 - 6.6e-16 58.1 0.2 8.5e-16 57.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF4430 PF14478.6 KFM72995.1 - 0.014 16.0 0.5 0.03 14.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) DDE_3 PF13358.6 KFM72996.1 - 0.0046 16.7 0.7 0.005 16.6 0.7 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease HLH PF00010.26 KFM72997.1 - 3.4e-15 55.7 1.5 3.4e-15 55.7 1.5 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4142 PF13628.6 KFM72997.1 - 0.067 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Macoilin PF09726.9 KFM72997.1 - 0.44 9.1 9.2 0.44 9.0 9.2 1.2 1 0 0 1 1 1 0 Macoilin family RXLR PF16810.5 KFM72997.1 - 0.46 10.9 4.5 1 9.8 4.5 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Tmemb_cc2 PF10267.9 KFM72997.1 - 0.47 9.5 7.7 0.71 9.0 7.7 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Dicty_REP PF05086.12 KFM72997.1 - 1 7.2 11.1 1.4 6.8 11.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Menin PF05053.13 KFM72997.1 - 3 6.1 7.2 3.8 5.8 7.2 1.1 1 0 0 1 1 1 0 Menin Zip PF02535.22 KFM72998.1 - 1.6e-11 44.1 2.9 1.9e-11 43.7 2.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Arfaptin PF06456.13 KFM73000.1 - 1.3e-75 254.0 3.4 1.6e-75 253.6 3.4 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR_3 PF16746.5 KFM73000.1 - 0.0016 18.2 1.3 0.026 14.2 1.3 2.2 1 1 0 1 1 1 1 BAR domain of APPL family DUF3929 PF13066.6 KFM73000.1 - 0.096 12.8 0.1 0.33 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) DUF3385 PF11865.8 KFM73001.1 - 0.064 13.2 0.6 9.7 6.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) NopRA1 PF16201.5 KFM73003.1 - 4.7e-49 166.7 1.1 1.4e-48 165.1 0.5 2.0 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 An_peroxidase PF03098.15 KFM73005.1 - 3.2e-185 616.7 0.0 4.9e-185 616.1 0.0 1.3 1 0 0 1 1 1 1 Animal haem peroxidase Ndc1_Nup PF09531.10 KFM73006.1 - 9.9e-06 24.5 8.5 1.2e-05 24.3 8.5 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Ndc1_Nup PF09531.10 KFM73007.1 - 9.8e-21 74.1 0.0 1.2e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Importin_rep_2 PF18786.1 KFM73007.1 - 0.056 13.3 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Importin 13 repeat TC1 PF15063.6 KFM73007.1 - 0.094 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Thyroid cancer protein 1 DER1 PF04511.15 KFM73008.1 - 1e-73 247.3 15.6 1.2e-73 247.1 15.6 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 KFM73008.1 - 0.00034 20.3 0.8 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 Oleosin Radial_spoke_3 PF06098.11 KFM73010.1 - 3.8e-35 121.6 11.2 4.7e-35 121.3 11.2 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 Swi5 PF07061.11 KFM73011.1 - 0.0081 16.2 0.4 0.017 15.2 0.4 1.4 1 0 0 1 1 1 1 Swi5 FlaC_arch PF05377.11 KFM73011.1 - 0.021 15.2 2.0 0.039 14.3 2.0 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 KFM73011.1 - 0.023 15.0 0.2 0.048 14.0 0.2 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels COG2 PF06148.11 KFM73011.1 - 0.029 14.5 0.4 0.043 13.9 0.4 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Csm1_N PF18504.1 KFM73011.1 - 0.03 14.7 0.4 12 6.3 0.0 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain Prefoldin_2 PF01920.20 KFM73011.1 - 0.041 13.8 0.5 0.075 13.0 0.5 1.5 1 0 0 1 1 1 0 Prefoldin subunit ABC_tran_CTD PF16326.5 KFM73011.1 - 0.063 13.5 2.2 3.7 7.9 0.0 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain HMMR_N PF15905.5 KFM73011.1 - 0.11 12.0 1.8 0.13 11.8 1.7 1.3 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4371 PF14291.6 KFM73012.1 - 4.3e-05 23.3 0.0 7.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) MCM_lid PF17855.1 KFM73012.1 - 0.032 14.7 0.6 0.078 13.4 0.6 1.6 1 0 0 1 1 1 0 MCM AAA-lid domain NPA PF16469.5 KFM73012.1 - 0.094 13.3 0.8 0.45 11.1 0.3 2.3 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 RT_RNaseH_2 PF17919.1 KFM73013.1 - 5.8e-25 87.2 0.0 8.7e-25 86.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM73013.1 - 2e-18 66.6 0.0 4.6e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM73013.1 - 2.8e-10 40.1 0.0 4.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YWFCY PF14293.6 KFM73013.1 - 0.46 10.8 0.2 0.46 10.8 0.2 2.0 2 0 0 2 2 2 0 YWFCY protein Pkinase PF00069.25 KFM73014.1 - 1e-14 54.5 0.0 2.1e-14 53.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73014.1 - 1.2e-07 31.3 0.0 6.7e-07 28.8 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM73014.1 - 2e-05 24.1 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM73014.1 - 0.028 14.4 0.0 0.067 13.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFM73014.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family HEAT PF02985.22 KFM73015.1 - 1.1e-19 68.9 1.1 0.0001 22.2 0.2 5.6 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 KFM73015.1 - 2.1e-07 31.2 0.0 0.0031 17.9 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KFM73015.1 - 3.7e-07 30.7 1.9 0.32 11.6 0.0 4.5 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFM73015.1 - 4.2e-07 30.3 0.0 5.9e-06 26.7 0.0 2.9 3 0 0 3 3 3 1 HEAT-like repeat IFRD PF05004.13 KFM73015.1 - 0.00078 18.6 0.0 0.046 12.8 0.0 2.5 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 KFM73015.1 - 0.0019 18.2 0.0 0.082 12.9 0.0 3.2 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KFM73015.1 - 0.0023 17.6 0.0 2.9 7.4 0.0 3.6 3 1 1 4 4 4 1 CLASP N terminal MMS19_N PF14500.6 KFM73015.1 - 0.049 13.2 0.1 3.4 7.2 0.0 2.7 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II UME PF08064.13 KFM73015.1 - 0.051 13.5 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 UME (NUC010) domain T_hemolysin PF12261.8 KFM73015.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Thermostable hemolysin HTH_Tnp_Tc3_2 PF01498.18 KFM73016.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73016.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73016.1 - 1.8e-07 30.8 1.2 6.7e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73016.1 - 0.0011 18.7 0.2 0.0072 16.1 0.6 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73016.1 - 0.026 14.6 0.4 0.086 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM73016.1 - 2 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM73017.1 - 8.1e-11 41.9 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73017.1 - 1e-08 35.3 0.8 2.1e-08 34.3 0.8 1.5 1 0 0 1 1 1 1 Transposase Peripla_BP_2 PF01497.18 KFM73019.1 - 0.0024 17.5 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein DUF1270 PF06900.11 KFM73019.1 - 0.0041 17.5 0.4 0.0097 16.3 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1270) TatC PF00902.18 KFM73020.1 - 0.0086 15.9 0.2 0.018 14.9 0.2 1.4 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF2298 PF10060.9 KFM73020.1 - 0.016 14.0 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) DUF3165 PF11364.8 KFM73020.1 - 0.098 13.0 1.8 7.9 6.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) ATP-grasp_4 PF13535.6 KFM73022.1 - 5.9e-05 22.7 0.0 0.00026 20.6 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain TauD PF02668.16 KFM73022.1 - 8.7e-05 22.4 0.1 0.00049 20.0 0.0 2.1 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family ATP-grasp PF02222.22 KFM73022.1 - 0.0002 21.0 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFM73022.1 - 0.0003 20.4 0.0 0.0021 17.6 0.0 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KFM73022.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RNase_H PF00075.24 KFM73022.1 - 0.034 14.3 0.6 0.081 13.1 0.6 1.6 1 0 0 1 1 1 0 RNase H Sigma_M_inh PF17453.2 KFM73024.1 - 0.0062 16.9 0.8 0.02 15.3 0.1 2.2 2 0 0 2 2 2 1 Sigma-M inhibitor DUF2417 PF10329.9 KFM73024.1 - 0.2 11.1 7.5 0.15 11.4 0.3 2.6 2 1 0 2 2 2 0 Region of unknown function (DUF2417) ATP-synt_A PF00119.20 KFM73024.1 - 0.86 9.5 10.5 2.8 7.8 8.8 2.5 2 1 0 2 2 2 0 ATP synthase A chain DHHC PF01529.20 KFM73024.1 - 1.2 9.2 8.7 7.3 6.7 0.2 3.1 2 1 1 3 3 3 0 DHHC palmitoyltransferase PAC2 PF09754.9 KFM73025.1 - 2.5e-26 93.0 0.0 3e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 PAC2 family FCH PF00611.23 KFM73026.1 - 1.2e-15 57.6 0.0 1.2e-15 57.6 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain zf-C2H2 PF00096.26 KFM73027.1 - 7.7e-23 79.6 39.9 1.2e-05 25.5 1.0 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM73027.1 - 1.1e-20 73.0 42.6 7.7e-09 35.6 0.4 6.1 6 0 0 6 6 5 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM73027.1 - 6.1e-17 60.9 38.6 0.00036 21.1 1.0 5.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM73027.1 - 8.1e-16 57.8 34.9 5e-05 23.5 0.7 5.0 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM73027.1 - 3.6e-10 39.4 28.5 2.1e-06 27.4 1.7 5.5 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM73027.1 - 1.1e-07 31.9 39.0 0.0039 17.5 2.7 5.6 5 1 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-CCHC_2 PF13696.6 KFM73027.1 - 0.0017 18.1 22.8 0.38 10.6 0.6 4.4 4 0 0 4 4 4 2 Zinc knuckle HypA PF01155.19 KFM73027.1 - 0.0051 16.8 10.4 7.9 6.5 0.6 2.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA BolA PF01722.18 KFM73027.1 - 0.0061 16.8 1.5 2 8.8 0.2 3.3 1 1 2 3 3 3 1 BolA-like protein NusB PF01029.18 KFM73027.1 - 0.0089 16.3 0.1 0.6 10.4 0.0 2.5 1 1 2 3 3 3 1 NusB family zf-Dof PF02701.15 KFM73027.1 - 0.014 15.5 1.0 0.014 15.5 1.0 3.4 1 1 2 3 3 3 0 Dof domain, zinc finger zf_UBZ PF18439.1 KFM73027.1 - 0.066 12.8 14.9 3.6 7.3 0.6 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM73027.1 - 0.071 13.2 12.0 7.4 6.8 2.4 3.9 1 1 3 4 4 4 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFM73027.1 - 0.1 12.6 36.5 0.14 12.2 0.5 5.8 5 3 0 5 5 5 0 C2H2-type zinc finger DUF3785 PF12653.7 KFM73027.1 - 0.1 12.7 5.5 0.4 10.8 0.7 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3785) Zn_ribbon_SprT PF17283.2 KFM73027.1 - 0.12 12.3 17.4 1.1 9.3 0.1 4.3 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf-C2H2_2 PF12756.7 KFM73027.1 - 0.17 12.2 30.0 4.4 7.7 0.9 5.0 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF2039 PF10217.9 KFM73027.1 - 0.5 10.7 15.1 0.71 10.3 5.6 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.12 KFM73027.1 - 0.63 10.1 16.9 1.9 8.5 1.3 3.8 1 1 2 3 3 3 0 zinc-ribbons zf-C2HC_2 PF13913.6 KFM73027.1 - 0.67 9.9 0.2 0.67 9.9 0.2 6.0 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFM73027.1 - 1.3 9.2 17.1 22 5.2 3.8 4.0 1 1 2 3 3 3 0 KIAA1045 RING finger FYVE PF01363.21 KFM73027.1 - 3.2 7.9 19.2 4.1 7.6 9.7 3.3 1 1 2 3 3 3 0 FYVE zinc finger zf-MYST PF17772.1 KFM73027.1 - 3.5 7.3 27.9 1.9 8.2 0.4 4.7 1 1 4 5 5 5 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFM73027.1 - 5.3 7.9 16.6 6.7 7.5 4.0 2.9 1 1 1 3 3 3 0 zinc-ribbon family PRE_C2HC PF07530.11 KFM73028.1 - 0.0034 17.4 2.1 0.0084 16.2 2.1 1.7 1 0 0 1 1 1 1 Associated with zinc fingers PyocinActivator PF11112.8 KFM73028.1 - 0.064 13.4 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Pyocin activator protein PrtN zf-CCHC PF00098.23 KFM73028.1 - 0.39 10.9 7.2 0.17 12.1 0.8 2.9 2 1 0 2 2 2 0 Zinc knuckle CBM_14 PF01607.24 KFM73030.1 - 1e-22 80.0 27.6 1.7e-09 37.7 5.6 3.6 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Tai4 PF16695.5 KFM73030.1 - 0.044 14.3 0.2 0.18 12.3 0.2 2.1 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein HGTP_anticodon PF03129.20 KFM73031.1 - 2.2e-08 34.1 0.0 4.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain DDE_Tnp_4 PF13359.6 KFM73032.1 - 8.9e-15 54.7 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM73032.1 - 1.1e-06 28.4 0.0 1.4e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein amfpi-1 PF12190.8 KFM73032.1 - 0.0059 17.2 0.7 0.013 16.1 0.8 1.5 1 1 1 2 2 2 1 Fungal protease inhibitor DDE_Tnp_1_2 PF13586.6 KFM73032.1 - 0.13 12.7 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain ST7 PF04184.12 KFM73033.1 - 5.4e-109 365.1 0.2 6.3e-109 364.9 0.2 1.0 1 0 0 1 1 1 1 ST7 protein ST7 PF04184.12 KFM73034.1 - 2.6e-165 550.9 0.9 2.9e-165 550.8 0.9 1.0 1 0 0 1 1 1 1 ST7 protein Clathrin PF00637.20 KFM73034.1 - 0.00074 19.4 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_6 PF13174.6 KFM73034.1 - 0.059 14.0 0.0 0.24 12.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Ceramidase_alk PF04734.13 KFM73035.1 - 6.4e-10 38.3 0.4 7.1e-10 38.1 0.4 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal LPAM_2 PF13627.6 KFM73035.1 - 3.4 7.6 5.6 6.4 6.8 5.6 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site HTH_Tnp_Tc3_2 PF01498.18 KFM73036.1 - 2.2e-16 59.9 2.8 5.3e-16 58.6 2.2 2.0 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM73036.1 - 7e-13 48.6 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73036.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73036.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73036.1 - 2.1 9.0 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ASXH PF13919.6 KFM73037.1 - 2.5e-10 40.5 0.1 2.5e-10 40.5 0.1 1.0 1 0 0 1 1 1 1 Asx homology domain Sushi PF00084.20 KFM73039.1 - 1.3e-35 121.8 19.6 5.4e-12 46.1 2.2 4.5 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) Lectin_C PF00059.21 KFM73039.1 - 1.2e-12 48.5 0.5 2.8e-12 47.3 0.5 1.7 1 0 0 1 1 1 1 Lectin C-type domain F5_F8_type_C PF00754.25 KFM73039.1 - 0.0034 17.5 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain EphA2_TM PF14575.6 KFM73039.1 - 0.057 14.3 0.0 0.12 13.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2970 PF11174.8 KFM73039.1 - 0.14 12.0 1.8 0.24 11.3 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) zf-CCCH_4 PF18044.1 KFM73040.1 - 9.2e-07 28.5 5.1 3e-06 26.9 5.1 1.9 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFM73040.1 - 5.8e-06 26.2 8.5 1.6e-05 24.7 8.5 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFM73040.1 - 0.0015 18.4 4.0 0.0015 18.4 4.0 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFM73040.1 - 0.0018 19.0 0.0 0.0018 19.0 0.0 3.2 2 1 1 3 3 3 1 Torus domain Pep_M12B_propep PF01562.19 KFM73041.1 - 1.3e-09 38.4 0.0 1.6e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Reprolysin family propeptide UPF0370 PF13980.6 KFM73042.1 - 0.0042 17.1 0.2 0.0066 16.4 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0370) BPD_transp_2 PF02653.16 KFM73042.1 - 0.056 12.6 0.1 0.065 12.4 0.1 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component EGF_3 PF12947.7 KFM73042.1 - 0.073 13.3 3.2 0.35 11.1 0.4 2.5 2 0 0 2 2 2 0 EGF domain HTH_28 PF13518.6 KFM73043.1 - 2.3e-05 24.4 0.1 2.3e-05 24.4 0.1 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73043.1 - 0.00089 19.0 0.1 0.0022 17.8 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM73043.1 - 0.0054 16.3 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_ISL3 PF13542.6 KFM73043.1 - 0.0085 15.5 0.9 0.037 13.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1 PF01527.20 KFM73043.1 - 0.012 15.9 0.1 0.014 15.7 0.1 1.3 1 1 0 1 1 1 0 Transposase Zip PF02535.22 KFM73044.1 - 0.26 10.5 0.8 0.29 10.3 0.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SpoVAE PF14097.6 KFM73045.1 - 0.12 12.0 0.1 0.73 9.5 0.0 2.1 1 1 1 2 2 2 0 Stage V sporulation protein AE1 I-set PF07679.16 KFM73046.1 - 4.7e-10 39.4 0.0 5.7e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM73046.1 - 1.9e-08 34.8 0.2 2.3e-08 34.5 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM73046.1 - 4.8e-08 33.2 0.2 5.8e-08 33.0 0.2 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM73046.1 - 7.4e-07 29.3 0.0 8.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain C1-set PF07654.15 KFM73046.1 - 0.023 15.1 0.2 0.056 13.8 0.2 1.7 1 1 0 1 1 1 0 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM73046.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.4 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Ig_3 PF13927.6 KFM73047.1 - 1.6e-15 57.5 0.4 2.6e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM73047.1 - 4.5e-13 49.1 0.1 2.9e-08 33.7 0.0 2.3 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM73047.1 - 1.6e-08 34.8 0.1 0.00055 20.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM73047.1 - 7.9e-07 29.2 0.0 6.4e-05 23.1 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFM73047.1 - 4e-06 26.9 0.1 0.00072 19.7 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM73047.1 - 0.026 14.5 0.0 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 C17orf99 Ig domain G6B PF15096.6 KFM73047.1 - 0.2 11.4 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 G6B family I-set PF07679.16 KFM73048.1 - 1.6e-52 175.5 0.0 1.7e-17 63.2 0.0 4.0 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM73048.1 - 8.8e-52 173.6 0.2 6.8e-16 58.6 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFM73048.1 - 5.5e-30 103.4 0.0 1.7e-09 37.7 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFM73048.1 - 8.6e-29 99.7 0.0 1.5e-09 38.0 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFM73048.1 - 4.8e-15 55.7 0.8 0.026 14.7 0.0 6.4 4 3 2 6 6 6 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM73048.1 - 2.5e-14 53.1 0.1 2e-06 27.8 0.0 4.1 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM73048.1 - 2.5e-06 27.8 0.0 0.034 14.6 0.0 3.8 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM73048.1 - 0.00068 19.2 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM73048.1 - 0.0062 16.5 0.3 4.8 7.3 0.0 3.8 4 1 0 4 4 4 1 C17orf99 Ig domain C1-set PF07654.15 KFM73048.1 - 0.033 14.6 0.1 0.91 9.9 0.0 3.2 4 1 0 4 4 4 0 Immunoglobulin C1-set domain Lep_receptor_Ig PF06328.11 KFM73048.1 - 0.042 13.8 0.4 2 8.4 0.0 2.9 4 0 0 4 4 4 0 Ig-like C2-type domain I-set PF07679.16 KFM73049.1 - 7.1e-16 58.1 0.0 7.5e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM73049.1 - 2.6e-13 50.4 0.0 2.9e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM73049.1 - 6.6e-11 42.4 0.0 7.1e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM73049.1 - 4.2e-09 36.5 0.0 5.2e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM73049.1 - 0.00057 20.0 0.2 0.0041 17.3 0.1 1.9 1 1 1 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM73049.1 - 0.0078 16.3 0.0 0.0084 16.2 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM73049.1 - 0.013 15.9 0.1 0.028 14.8 0.1 1.5 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM73049.1 - 0.043 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFM73050.1 - 2.6e-36 123.6 0.1 4.5e-13 49.1 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM73050.1 - 6.7e-36 122.7 1.6 1.1e-15 58.0 0.1 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM73050.1 - 4.3e-24 84.7 0.6 2.3e-08 34.3 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM73050.1 - 6.9e-18 64.6 0.2 2.7e-05 24.3 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM73050.1 - 9.1e-07 29.0 1.9 2.8 8.2 0.0 4.8 3 2 1 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM73050.1 - 1.7e-06 27.5 0.3 0.17 11.4 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFM73050.1 - 2.5e-06 27.2 1.7 0.34 10.7 0.1 3.3 3 0 0 3 3 3 2 Adenovirus E3 region protein CR1 Receptor_2B4 PF11465.8 KFM73050.1 - 3.4e-06 27.2 0.6 0.37 11.0 0.0 3.1 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 Herpes_gE PF02480.16 KFM73050.1 - 0.00094 18.0 0.0 1.1 7.9 0.0 3.0 3 0 0 3 3 3 1 Alphaherpesvirus glycoprotein E Ig_4 PF16680.5 KFM73050.1 - 0.0014 18.9 0.2 2.4 8.5 0.0 3.4 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM73050.1 - 0.0019 18.2 0.0 0.53 10.4 0.0 3.0 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFM73050.1 - 0.027 14.5 0.0 0.62 10.2 0.0 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFM73051.1 - 1.5e-103 339.1 0.5 9.7e-18 64.0 0.1 7.1 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM73051.1 - 9e-89 292.2 7.4 2.8e-14 53.5 0.2 7.1 7 0 0 7 7 7 7 Immunoglobulin domain Ig_2 PF13895.6 KFM73051.1 - 8.5e-69 227.9 0.5 2e-10 40.9 0.0 7.1 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 KFM73051.1 - 4.9e-54 180.5 0.0 2.3e-07 30.9 0.1 7.4 7 0 0 7 7 7 7 Immunoglobulin domain V-set PF07686.17 KFM73051.1 - 1.8e-20 73.1 8.5 0.19 11.9 0.0 11.0 7 4 1 8 8 8 5 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM73051.1 - 7.3e-20 70.3 0.0 0.00087 18.8 0.0 7.3 7 0 0 7 7 7 5 Immunoglobulin domain Ig_5 PF16681.5 KFM73051.1 - 5.3e-18 65.2 0.0 0.052 13.9 0.0 8.1 7 1 0 7 7 7 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM73051.1 - 6.7e-17 61.3 0.0 0.0039 17.2 0.0 6.5 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM73051.1 - 7.5e-16 58.2 1.0 0.84 9.9 0.1 8.7 7 4 0 7 7 7 4 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFM73051.1 - 5.6e-11 42.7 0.3 0.084 13.3 0.0 6.3 6 0 0 6 6 6 2 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFM73051.1 - 1.3e-09 37.9 0.3 1.2 9.3 0.0 7.3 7 1 0 7 7 7 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFM73051.1 - 5.2e-09 36.0 0.2 4.3 7.5 0.0 6.6 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 KFM73051.1 - 7.1e-08 32.5 0.0 0.23 11.7 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin C2-set domain Herpes_gE PF02480.16 KFM73051.1 - 1.8e-05 23.7 0.1 3.8 6.2 0.0 5.3 4 1 0 5 5 5 1 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.8 KFM73051.1 - 5.7e-05 23.3 2.1 22 5.3 0.0 5.9 7 0 0 7 7 7 0 Natural killer cell receptor 2B4 Herpes_gI PF01688.17 KFM73051.1 - 0.018 15.0 0.0 39 4.1 0.0 3.8 4 0 0 4 4 4 0 Alphaherpesvirus glycoprotein I DUF3954 PF13128.6 KFM73051.1 - 0.04 13.7 0.2 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3954) I-set PF07679.16 KFM73052.1 - 1.1e-12 47.8 0.1 5e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM73052.1 - 7.9e-10 39.2 0.4 6e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM73052.1 - 4.8e-09 36.4 0.2 0.00034 20.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM73052.1 - 0.00017 21.7 0.0 0.4 10.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM73052.1 - 0.0054 16.9 0.0 0.29 11.3 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM73052.1 - 0.039 13.5 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 KFM73053.1 - 1.2e-130 425.9 0.0 1.2e-17 63.8 0.0 8.3 8 0 0 8 8 8 8 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM73053.1 - 8e-117 382.1 13.7 5.8e-17 62.1 0.1 8.3 8 0 0 8 8 8 8 Immunoglobulin domain Ig_2 PF13895.6 KFM73053.1 - 1e-81 269.3 1.0 1.9e-11 44.1 0.0 8.3 8 0 0 8 8 8 8 Immunoglobulin domain ig PF00047.25 KFM73053.1 - 3.8e-79 260.9 0.3 2.1e-12 47.0 0.0 8.7 8 0 0 8 8 8 8 Immunoglobulin domain TSP_1 PF00090.19 KFM73053.1 - 9.4e-35 118.6 37.3 1.1e-11 44.7 7.4 3.5 3 0 0 3 3 3 3 Thrombospondin type 1 domain V-set PF07686.17 KFM73053.1 - 4.7e-32 110.4 17.0 0.0049 17.0 0.0 14.3 8 7 2 10 10 10 7 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM73053.1 - 4.8e-31 107.0 0.0 6.1e-05 23.3 0.0 8.5 8 0 0 8 8 8 8 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM73053.1 - 1.9e-30 104.8 0.1 0.00089 19.3 0.0 7.6 7 0 0 7 7 7 7 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM73053.1 - 2.7e-23 81.3 0.0 0.052 13.1 0.0 8.6 8 0 0 8 8 8 6 Immunoglobulin domain Ig_4 PF16680.5 KFM73053.1 - 5.8e-22 77.7 0.0 0.032 14.5 0.0 8.2 8 0 0 8 8 8 6 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFM73053.1 - 2.9e-15 56.1 2.8 0.016 15.3 0.0 8.4 7 2 1 8 8 8 3 C17orf99 Ig domain C1-set PF07654.15 KFM73053.1 - 1.4e-10 41.4 0.8 0.59 10.5 0.0 7.6 7 1 0 7 7 7 2 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFM73053.1 - 2.7e-08 33.8 0.0 5.2 7.2 0.0 7.9 9 0 0 9 9 9 1 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFM73053.1 - 3.7e-07 29.8 0.2 3.9 7.3 0.0 6.9 7 0 0 7 7 7 1 Adenovirus E3 region protein CR1 Receptor_2B4 PF11465.8 KFM73053.1 - 0.005 17.0 5.4 0.81 9.9 0.0 5.6 7 1 1 8 8 8 1 Natural killer cell receptor 2B4 LVIVD PF08309.11 KFM73053.1 - 0.037 13.3 6.4 20 4.6 0.1 4.6 5 0 0 5 5 5 0 LVIVD repeat PhoLip_ATPase_C PF16212.5 KFM73054.1 - 1.6e-18 67.4 13.4 1.9e-18 67.1 13.4 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal DUF1240 PF06836.12 KFM73054.1 - 0.23 12.0 3.2 0.13 12.8 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) Ldl_recept_a PF00057.18 KFM73056.1 - 2.4e-23 82.0 50.7 3.4e-10 40.0 11.1 4.2 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A DUF5478 PF17572.2 KFM73056.1 - 2 8.6 8.5 0.18 11.9 0.9 2.6 1 1 2 3 3 3 0 Family of unknown function (DUF5478) Hist_deacetyl PF00850.19 KFM73057.1 - 1.9e-82 277.2 0.0 3.5e-82 276.3 0.0 1.4 1 1 1 2 2 2 1 Histone deacetylase domain HTH_Tnp_Tc3_2 PF01498.18 KFM73058.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73058.1 - 9.9e-14 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM73059.1 - 3.6e-14 52.7 0.0 5.5e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.18 KFM73059.1 - 1.9e-05 24.6 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.6 KFM73059.1 - 0.0007 19.7 0.1 0.0014 18.7 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain SAB PF04382.13 KFM73059.1 - 0.081 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 SAB domain Toxin_37 PF11415.8 KFM73059.1 - 0.21 11.4 1.1 0.69 9.8 0.8 1.9 2 0 0 2 2 2 0 Antifungal peptide termicin HTH_Tnp_Tc3_2 PF01498.18 KFM73061.1 - 6.1e-16 58.4 8.2 1.1e-15 57.6 8.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73061.1 - 7.7e-16 58.2 0.8 5.7e-15 55.3 0.0 2.5 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM73061.1 - 0.00072 20.1 2.5 0.00072 20.1 2.5 2.9 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM73061.1 - 0.0022 17.7 0.2 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73061.1 - 0.014 15.5 0.1 0.063 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM73061.1 - 0.032 14.3 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix PIF1 PF05970.14 KFM73062.1 - 3.3e-16 59.4 0.1 4.6e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase HTH_Tnp_Tc3_2 PF01498.18 KFM73063.1 - 2.6e-16 59.6 2.8 4.8e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73063.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73063.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73063.1 - 0.0023 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73063.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM73064.1 - 2.7e-08 33.7 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 KFM73065.1 - 1.1e-30 105.6 0.0 5e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM73065.1 - 2.9e-29 101.4 0.0 1.4e-28 99.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM73065.1 - 2.2e-28 99.3 0.1 5.8e-28 97.9 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM73065.1 - 2.1e-18 66.6 0.0 3.7e-17 62.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM73065.1 - 2.3e-16 59.6 0.0 8e-16 57.9 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Arc_C PF18162.1 KFM73065.1 - 4e-05 23.4 1.7 0.00014 21.7 0.4 2.6 3 0 0 3 3 3 1 Arc C-lobe 7tm_1 PF00001.21 KFM73065.1 - 5.7e-05 22.6 0.0 8.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-H2C2 PF09337.10 KFM73065.1 - 0.0016 18.6 0.0 0.0042 17.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM73065.1 - 0.025 14.8 2.8 0.24 11.7 0.0 3.7 3 0 0 3 3 3 0 Retrotransposon gag protein Chitin_bind_4 PF00379.23 KFM73066.1 - 1.4e-10 41.5 4.9 1.9e-10 41.1 4.9 1.2 1 0 0 1 1 1 1 Insect cuticle protein AhpC-TSA_2 PF13911.6 KFM73067.1 - 0.00012 22.2 0.0 0.00014 22.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme CRAL_TRIO_2 PF13716.6 KFM73067.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain ACBP PF00887.19 KFM73068.1 - 3.8e-27 94.3 0.1 6.6e-27 93.6 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein MCC-bdg_PDZ PF10506.9 KFM73068.1 - 0.29 11.2 1.6 0.32 11.0 0.2 1.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ion_trans_2 PF07885.16 KFM73069.1 - 3.5e-14 52.5 15.4 6.2e-11 42.1 1.0 2.6 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFM73069.1 - 0.00017 20.9 7.8 0.0017 17.6 0.1 2.6 2 1 0 2 2 2 2 Ion transport protein IRK PF01007.20 KFM73069.1 - 3.1 7.6 7.8 5.7 6.7 0.0 3.4 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain Transposase_1 PF01359.18 KFM73071.1 - 5.6e-12 45.3 0.1 7.3e-12 45.0 0.1 1.2 1 0 0 1 1 1 1 Transposase (partial DDE domain) zf-DNA_Pol PF08996.10 KFM73071.1 - 0.076 12.8 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger ZZ PF00569.17 KFM73072.1 - 2e-12 46.7 6.4 3.5e-12 45.9 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KFM73072.1 - 5.5e-05 23.4 5.2 0.00011 22.4 5.2 1.5 1 0 0 1 1 1 1 C1 domain EF-hand_3 PF09069.11 KFM73072.1 - 0.015 15.7 0.7 0.015 15.7 0.7 2.4 2 1 0 2 2 2 0 EF-hand Jnk-SapK_ap_N PF09744.9 KFM73072.1 - 0.059 13.6 10.9 0.1 12.9 10.9 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 KFM73072.1 - 0.066 11.8 8.5 0.085 11.4 8.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Dict-STAT-coil PF09267.10 KFM73072.1 - 0.081 13.3 6.2 0.18 12.2 6.2 1.5 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil DehI PF10778.9 KFM73072.1 - 0.1 12.7 0.8 0.19 11.9 0.8 1.4 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI Macoilin PF09726.9 KFM73072.1 - 0.17 10.4 5.4 0.2 10.2 5.4 1.1 1 0 0 1 1 1 0 Macoilin family STAT_alpha PF01017.20 KFM73072.1 - 0.21 11.5 11.3 0.35 10.8 11.3 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain Seryl_tRNA_N PF02403.22 KFM73072.1 - 0.27 11.5 9.3 0.48 10.7 9.3 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TolA_bind_tri PF16331.5 KFM73072.1 - 0.39 10.8 17.5 0.47 10.6 11.7 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF2312 PF10073.9 KFM73072.1 - 0.54 9.9 5.8 0.34 10.6 0.6 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) APG6_N PF17675.1 KFM73072.1 - 0.71 10.4 17.2 3.2 8.3 8.0 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 KFM73072.1 - 0.98 7.9 5.4 1.3 7.5 5.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CRISPR_Cse2 PF09485.10 KFM73072.1 - 2 9.0 7.8 3.7 8.1 7.5 1.6 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) WDCP PF15390.6 KFM73072.1 - 2.3 6.5 6.1 3 6.1 6.1 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family CENP-H PF05837.12 KFM73072.1 - 2.6 8.5 15.2 2.3 8.7 7.0 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Prefoldin_2 PF01920.20 KFM73072.1 - 3.3 7.7 13.2 1.7 8.7 3.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.15 KFM73072.1 - 3.9 7.3 11.5 20 5.0 4.6 2.3 1 1 1 2 2 2 0 Septum formation initiator kleA_kleC PF17383.2 KFM73072.1 - 8.3 6.8 7.2 0.71 10.2 1.3 2.0 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A EF-hand_2 PF09068.11 KFM73073.1 - 3.7e-40 136.9 0.4 4.7e-40 136.5 0.4 1.1 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 KFM73073.1 - 1.1e-13 51.4 0.0 3.9e-13 49.6 0.0 1.9 3 0 0 3 3 3 1 EF-hand Ig_2 PF13895.6 KFM73074.1 - 4e-08 33.5 0.0 1.1e-07 32.1 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM73074.1 - 5.1e-08 33.4 0.0 7.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM73074.1 - 3.5e-07 30.4 0.0 4.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFM73074.1 - 4.9e-07 29.8 0.0 3.4e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM73074.1 - 0.00015 21.7 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain DUF5066 PF16728.5 KFM73074.1 - 0.038 13.3 0.0 0.044 13.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) Izumo-Ig PF16706.5 KFM73074.1 - 0.076 13.1 0.2 0.14 12.3 0.0 1.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM73075.1 - 2e-19 69.6 3.6 5.7e-19 68.1 2.1 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73075.1 - 3.7e-16 59.2 0.0 2.3e-15 56.6 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM73075.1 - 2.2e-07 30.8 0.4 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM73075.1 - 3.6e-07 30.7 2.0 3.6e-07 30.7 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73075.1 - 9.4e-07 28.9 2.3 7.6e-05 22.8 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73075.1 - 1.9e-06 27.5 3.4 2.5e-05 23.9 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM73075.1 - 2.8e-06 27.2 0.7 4e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM73075.1 - 0.00012 21.9 0.7 0.0017 18.2 0.0 2.5 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM73075.1 - 0.0009 19.2 0.7 0.016 15.2 0.0 2.6 2 1 1 3 3 3 1 Crp-like helix-turn-helix domain TrmB PF01978.19 KFM73075.1 - 0.0044 16.9 0.1 7.7 6.5 0.0 3.3 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB GntR PF00392.21 KFM73075.1 - 0.0088 15.7 0.1 0.11 12.2 0.0 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM73075.1 - 0.055 13.5 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM73075.1 - 0.078 13.2 0.1 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 KFM73075.1 - 0.14 12.3 0.0 30 4.8 0.0 2.7 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM73075.1 - 0.29 11.0 3.9 1.4 8.7 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM73075.1 - 0.98 8.9 3.6 7.1 6.1 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Hairy_orange PF07527.13 KFM73076.1 - 2.7e-19 69.1 0.3 5.6e-19 68.1 0.3 1.6 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 KFM73076.1 - 5.4e-16 58.3 6.4 9.2e-16 57.5 6.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM73077.1 - 1.7e-13 50.6 1.0 3.3e-13 49.7 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73077.1 - 3.7e-12 46.2 0.0 6.2e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM73077.1 - 0.00026 21.5 1.7 0.00026 21.5 1.7 2.0 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM73077.1 - 0.012 15.4 1.0 1 9.3 0.0 2.7 1 1 1 2 2 2 0 MarR family HTH_24 PF13412.6 KFM73077.1 - 0.044 13.4 1.2 6.6 6.4 0.0 3.2 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 KFM73077.1 - 0.071 13.2 0.1 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix HTH_23 PF13384.6 KFM73077.1 - 0.24 11.2 2.8 0.48 10.3 0.0 2.7 3 1 0 3 3 3 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM73077.1 - 0.28 11.2 1.7 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM73078.1 - 2.4e-16 59.8 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73078.1 - 9.7e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank_2 PF12796.7 KFM73079.1 - 1.4e-31 108.9 0.3 6.2e-15 55.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM73079.1 - 5.8e-31 106.5 2.5 3.8e-11 43.3 0.0 3.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFM73079.1 - 3.7e-29 99.9 0.9 1.8e-07 31.3 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KFM73079.1 - 2.4e-28 95.0 0.1 1.5e-05 25.0 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KFM73079.1 - 7e-27 93.2 1.9 8.8e-07 29.1 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF2520 PF10728.9 KFM73079.1 - 0.036 13.8 0.1 6.6 6.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2520) Ion_trans PF00520.31 KFM73080.1 - 2.4e-05 23.7 30.2 5e-05 22.7 30.2 1.6 1 1 0 1 1 1 1 Ion transport protein ERCC4 PF02732.15 KFM73082.1 - 3.2e-28 98.9 0.1 6e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain DDE_3 PF13358.6 KFM73084.1 - 2.9e-16 59.5 0.1 3.1e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73084.1 - 1.3e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73085.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease CSN8_PSD8_EIF3K PF10075.9 KFM73086.1 - 5e-32 110.9 0.0 6.8e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 KFM73086.1 - 0.00057 20.4 0.1 0.0023 18.4 0.1 2.0 1 1 0 1 1 1 1 PCI domain Paf67 PF10255.9 KFM73086.1 - 0.013 14.5 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 RVT_1 PF00078.27 KFM73087.1 - 0.032 13.8 0.4 0.16 11.5 0.1 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PRE_C2HC PF07530.11 KFM73088.1 - 5.6e-15 55.2 0.3 1.3e-14 54.0 0.3 1.7 1 0 0 1 1 1 1 Associated with zinc fingers GIT_CC PF16559.5 KFM73088.1 - 0.032 14.1 0.4 0.089 12.7 0.4 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Bac_RepA_C PF18008.1 KFM73088.1 - 0.073 13.4 5.4 0.045 14.1 2.0 2.5 2 0 0 2 2 2 0 Replication initiator protein A C-terminal domain Mto2_bdg PF12808.7 KFM73088.1 - 0.076 13.3 0.3 0.23 11.8 0.3 1.8 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Galactosyl_T PF01762.21 KFM73089.1 - 7.6e-31 107.5 0.1 1e-30 107.0 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF1638 PF07796.11 KFM73089.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) IL7 PF01415.16 KFM73090.1 - 0.77 9.8 7.1 0.66 10.0 4.8 2.0 1 1 1 2 2 2 0 Interleukin 7/9 family UCH PF00443.29 KFM73091.1 - 1.7e-25 90.0 0.1 3.3e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM73091.1 - 9.7e-19 68.1 0.0 2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.8 KFM73091.1 - 0.0033 16.4 2.5 0.29 10.0 0.2 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF3517) zf-ribbon_3 PF13248.6 KFM73091.1 - 0.037 13.4 0.3 0.13 11.7 0.3 1.9 1 0 0 1 1 1 0 zinc-ribbon domain DUF2841 PF11001.8 KFM73091.1 - 0.068 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) DNA_RNApol_7kD PF03604.13 KFM73091.1 - 0.29 10.9 1.4 3.8 7.3 1.1 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit UCH PF00443.29 KFM73092.1 - 8.3e-16 58.2 0.6 1.5e-15 57.4 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM73092.1 - 6.1e-05 22.8 2.1 7.2e-05 22.5 1.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HEAT PF02985.22 KFM73092.1 - 0.0042 17.2 0.2 7.9 7.0 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KFM73092.1 - 0.038 14.4 0.2 15 6.0 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats Atx10homo_assoc PF09759.9 KFM73092.1 - 0.15 12.1 0.0 0.58 10.2 0.0 1.9 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Nup188 PF10487.9 KFM73095.1 - 0.0034 15.4 0.1 0.0039 15.2 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DDE_1 PF03184.19 KFM73097.1 - 4.2e-50 169.8 0.1 7.6e-50 169.0 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM73097.1 - 1.9e-12 47.0 0.0 1.6e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM73097.1 - 0.00089 18.8 0.0 0.0031 17.1 0.0 2.1 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain CIMR PF00878.18 KFM73098.1 - 9.8e-25 87.3 0.1 1.7e-24 86.5 0.1 1.3 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat CIMR PF00878.18 KFM73099.1 - 1.2e-10 41.7 1.2 1.1e-09 38.5 0.4 2.0 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 KFM73099.1 - 2.7e-07 30.4 0.1 4e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.15 KFM73099.1 - 0.0014 17.8 0.5 0.026 13.6 0.0 2.0 2 0 0 2 2 2 2 Mannose-6-phosphate receptor CIMR PF00878.18 KFM73100.1 - 4.8e-40 136.9 5.5 4e-23 82.1 1.5 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KFM73100.1 - 1.6e-08 34.8 6.9 0.013 15.4 0.1 3.6 1 1 2 3 3 3 3 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KFM73100.1 - 3.1e-06 26.5 0.4 2.3e-05 23.6 0.2 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate receptor PRKCSH_1 PF13015.6 KFM73100.1 - 9.9e-05 22.1 0.2 0.00021 21.0 0.0 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein CIMR PF00878.18 KFM73101.1 - 9.8e-44 148.9 15.7 2.5e-18 66.5 1.5 4.1 4 0 0 4 4 4 4 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 KFM73101.1 - 1.7e-06 27.3 8.7 0.071 12.2 0.1 4.4 2 2 2 4 4 4 4 Mannose-6-phosphate receptor ATG27 PF09451.10 KFM73101.1 - 3e-06 27.3 12.8 0.0022 17.9 3.0 4.1 2 1 2 4 4 4 3 Autophagy-related protein 27 Methyltransf_25 PF13649.6 KFM73102.1 - 6.1e-12 46.1 0.0 1.1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFM73102.1 - 1.3e-10 41.1 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KFM73102.1 - 1e-09 38.9 0.0 2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM73102.1 - 2.7e-09 37.0 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM73102.1 - 3.1e-08 33.6 0.0 4.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFM73102.1 - 5.9e-07 29.0 0.1 8.1e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KFM73102.1 - 7.1e-06 26.7 0.0 1.2e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFM73102.1 - 2.4e-05 23.4 0.1 3.4e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KFM73102.1 - 9.2e-05 22.1 0.1 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KFM73102.1 - 0.00041 20.3 0.2 0.00067 19.6 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFM73102.1 - 0.00052 19.8 0.0 0.0025 17.6 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KFM73102.1 - 0.0036 16.7 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFM73102.1 - 0.0058 16.4 0.1 0.009 15.8 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_32 PF13679.6 KFM73102.1 - 0.0062 16.5 0.0 0.0098 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFM73102.1 - 0.014 16.4 0.0 0.025 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KFM73102.1 - 0.025 14.4 0.1 0.053 13.4 0.0 1.5 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase MetW PF07021.12 KFM73102.1 - 0.06 12.9 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 KFM73102.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase HTH_Tnp_ISL3 PF13542.6 KFM73103.1 - 0.00021 20.6 1.3 0.00024 20.5 0.4 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KFM73103.1 - 0.00068 19.4 0.1 0.00068 19.4 0.1 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73103.1 - 0.00095 19.2 0.5 0.0018 18.4 0.5 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM73103.1 - 0.00096 18.6 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 CENP-B_N PF04218.13 KFM73103.1 - 0.0058 16.2 0.1 0.026 14.2 0.0 1.8 1 1 1 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_37 PF13744.6 KFM73103.1 - 0.0076 16.2 0.1 0.0096 15.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 KFM73103.1 - 0.013 15.8 0.5 0.024 15.0 0.5 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM73103.1 - 0.014 15.4 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_38 PF13936.6 KFM73103.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 KFM73103.1 - 0.024 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix MarR_2 PF12802.7 KFM73103.1 - 0.036 13.9 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.6 KFM73103.1 - 0.041 13.9 0.2 0.06 13.4 0.2 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DUF134 PF02001.16 KFM73103.1 - 0.053 14.1 0.0 0.059 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_24 PF13412.6 KFM73103.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.7 KFM73103.1 - 0.079 13.2 0.1 0.19 11.9 0.0 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 KFM73103.1 - 0.17 11.8 0.5 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 HTH domain BTD PF09270.10 KFM73104.1 - 1.4e-76 255.9 0.0 2.3e-76 255.2 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 KFM73104.1 - 1.4e-49 168.6 0.6 4.1e-49 167.1 0.0 2.1 2 0 0 2 2 2 1 LAG1, DNA binding TIG PF01833.24 KFM73104.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 IPT/TIG domain NtA PF03146.15 KFM73109.1 - 1.6e-26 92.3 0.1 2.5e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 Agrin NtA domain Kazal_2 PF07648.15 KFM73109.1 - 2.8e-08 33.8 10.3 2.8e-08 33.8 10.3 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM73109.1 - 3.6e-08 33.3 9.4 3.6e-08 33.3 9.4 2.1 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Tnp_P_element PF12017.8 KFM73110.1 - 8.6e-23 80.9 0.0 1.2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Transposase protein TB2_DP1_HVA22 PF03134.19 KFM73114.1 - 0.0019 18.1 0.1 0.0033 17.3 0.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family LDcluster4 PF18306.1 KFM73115.1 - 1e-06 28.4 0.1 2.1e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 SLOG cluster4 family STALD PF18185.1 KFM73115.1 - 0.0018 17.6 0.0 0.41 10.0 0.0 2.2 2 0 0 2 2 2 2 Sir2- and TIR-associating SLOG family LD_cluster3 PF18180.1 KFM73115.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster3 family TGS PF02824.21 KFM73115.1 - 0.07 13.2 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 TGS domain CBFB_NFYA PF02045.15 KFM73115.1 - 0.089 13.4 2.1 0.94 10.1 0.0 2.4 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B SIMPL PF04402.14 KFM73115.1 - 0.42 11.0 4.0 18 5.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF541) TIR_2 PF13676.6 KFM73116.1 - 0.0024 18.4 0.0 1.9 9.1 0.0 2.5 2 0 0 2 2 2 2 TIR domain FTA4 PF13093.6 KFM73116.1 - 0.039 13.9 1.9 0.082 12.8 1.9 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 NleF_casp_inhib PF16809.5 KFM73116.1 - 0.057 13.3 0.3 0.096 12.6 0.3 1.3 1 0 0 1 1 1 0 NleF caspase inhibitor TIR_2 PF13676.6 KFM73117.1 - 5.9e-10 39.8 0.0 1.1e-09 39.0 0.0 1.4 1 0 0 1 1 1 1 TIR domain DDE_Tnp_1_7 PF13843.6 KFM73118.1 - 1.6e-34 119.8 0.0 1.9e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 G5 PF07501.12 KFM73118.1 - 0.31 11.5 2.2 0.26 11.7 0.6 1.7 2 0 0 2 2 2 0 G5 domain Ig_3 PF13927.6 KFM73119.1 - 2.8e-10 40.7 1.5 2.7e-05 24.7 0.1 3.1 2 1 1 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFM73119.1 - 5e-10 39.6 0.9 8.3e-05 22.8 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM73119.1 - 4.2e-06 26.9 0.4 0.0091 16.1 0.1 2.6 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM73119.1 - 1.5e-05 25.0 0.1 5.8e-05 23.1 0.0 2.0 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM73119.1 - 0.00041 20.5 1.5 0.22 11.7 0.1 2.7 2 1 1 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.16 KFM73119.1 - 0.0015 18.6 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set_2 PF15910.5 KFM73119.1 - 0.014 15.5 0.0 0.76 9.9 0.0 2.3 2 0 0 2 2 2 0 ICOS V-set domain Ig_4 PF16680.5 KFM73119.1 - 0.087 13.1 1.7 3.3 8.0 0.1 2.8 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain VWD PF00094.25 KFM73120.1 - 3.4e-27 95.6 0.2 3.4e-27 95.6 0.2 1.6 2 0 0 2 2 2 1 von Willebrand factor type D domain Sushi PF00084.20 KFM73120.1 - 2.1e-05 25.0 20.1 0.00095 19.7 4.9 3.2 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) Como_SCP PF02248.16 KFM73120.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Small coat protein Cpn60_TCP1 PF00118.24 KFM73121.1 - 2.1e-140 468.6 7.7 2.4e-140 468.4 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MMM1 PF10296.9 KFM73121.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 dsrm PF00035.26 KFM73122.1 - 1.2e-20 74.0 4.8 6.5e-08 33.2 0.1 4.9 4 0 0 4 4 4 4 Double-stranded RNA binding motif XTBD PF11952.8 KFM73122.1 - 1.7e-20 72.5 0.1 4.7e-20 71.1 0.1 1.8 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD R3H PF01424.22 KFM73122.1 - 1.6e-08 34.4 0.1 6.4e-08 32.5 0.1 2.1 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KFM73122.1 - 2e-08 34.0 1.7 4.5e-08 32.9 1.7 1.7 1 0 0 1 1 1 1 G-patch domain LPP20 PF02169.16 KFM73122.1 - 0.65 10.4 14.6 1.5 9.2 0.0 5.1 5 0 0 5 5 5 0 LPP20 lipoprotein Pkinase PF00069.25 KFM73124.1 - 3e-41 141.6 0.0 4.4e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73124.1 - 3e-16 59.5 0.0 5.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KFM73124.1 - 0.074 12.6 0.1 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase EMP24_GP25L PF01105.24 KFM73125.1 - 1.7e-22 80.3 0.3 2e-22 80.0 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Caudo_bapla_RBP PF08931.10 KFM73125.1 - 0.051 13.0 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Receptor-binding protein of phage tail base-plate Siphoviridae, head DDE_3 PF13358.6 KFM73126.1 - 2.6e-16 59.7 0.1 3.4e-15 56.1 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73126.1 - 1.4e-10 41.3 1.0 2.9e-10 40.3 1.0 1.6 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM73128.1 - 2.5e-16 59.6 2.2 4.6e-16 58.8 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73128.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_H PF00075.24 KFM73128.1 - 0.003 17.8 0.0 0.0061 16.7 0.0 1.5 1 0 0 1 1 1 1 RNase H HTH_Tnp_Tc3_2 PF01498.18 KFM73129.1 - 5.4e-16 58.6 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73129.1 - 1.3e-12 47.7 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73129.1 - 3.2e-07 30.0 0.2 7.2e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73129.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73129.1 - 2.3 8.9 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM73130.1 - 4.2e-16 59.0 0.1 5.1e-15 55.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73130.1 - 7.1e-16 58.2 6.5 1.3e-15 57.4 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM73130.1 - 0.00065 20.3 1.5 0.00065 20.3 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM73130.1 - 0.002 17.9 0.1 0.11 12.4 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73130.1 - 0.013 15.6 0.1 0.059 13.5 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM73130.1 - 0.025 14.6 2.4 0.032 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM73131.1 - 1.9e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73131.1 - 7.4e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM73132.1 - 4.2e-16 59.0 0.1 5.1e-15 55.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73132.1 - 7.1e-16 58.2 6.5 1.3e-15 57.4 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM73132.1 - 0.00065 20.3 1.5 0.00065 20.3 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM73132.1 - 0.002 17.9 0.1 0.11 12.4 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73132.1 - 0.013 15.6 0.1 0.059 13.5 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM73132.1 - 0.025 14.6 2.4 0.032 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Toxin_38 PF14866.6 KFM73133.1 - 0.0015 18.8 2.8 0.0016 18.7 2.8 1.1 1 0 0 1 1 1 1 Potassium channel toxin Toxin_3 PF00537.18 KFM73133.1 - 0.006 16.8 5.9 0.0077 16.4 5.9 1.2 1 0 0 1 1 1 1 Scorpion toxin-like domain DUF4018 PF13210.6 KFM73133.1 - 0.017 14.9 0.0 0.018 14.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Defensin_2 PF01097.18 KFM73133.1 - 0.15 12.0 4.7 0.2 11.6 4.7 1.3 1 0 0 1 1 1 0 Arthropod defensin DDE_3 PF13358.6 KFM73134.1 - 0.00017 21.4 0.0 0.00018 21.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KFM73135.1 - 1.6e-17 63.7 0.1 2.7e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM73135.1 - 4.7e-12 45.8 0.4 1.1e-11 44.6 0.4 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM73135.1 - 0.0022 17.7 0.0 0.0073 16.1 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73136.1 - 8.7e-16 57.9 6.5 1.5e-15 57.2 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73136.1 - 2.2e-12 47.0 0.0 5.5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM73136.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM73136.1 - 0.0042 16.8 0.3 0.12 12.2 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73136.1 - 0.018 15.2 0.1 0.065 13.4 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM73136.1 - 0.035 14.1 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM73137.1 - 4e-16 59.0 3.0 6.2e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73137.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73137.1 - 3.2e-07 30.0 1.6 7.6e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73137.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73137.1 - 3 8.5 15.6 0.13 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF4371 PF14291.6 KFM73138.1 - 0.012 15.2 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) DUF659 PF04937.15 KFM73139.1 - 4.3e-07 29.9 1.0 0.0071 16.2 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KFM73139.1 - 2.4e-06 27.3 0.0 5.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Propep_M14 PF02244.16 KFM73139.1 - 1.4 9.3 4.5 3.9 7.9 0.7 3.1 4 0 0 4 4 4 0 Carboxypeptidase activation peptide polyprenyl_synt PF00348.17 KFM73140.1 - 1.1e-75 254.0 0.0 1.4e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Elongin_A PF06881.11 KFM73141.1 - 5.1e-23 81.6 0.2 5.1e-23 81.6 0.2 2.6 2 1 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A JAB PF01398.21 KFM73142.1 - 4e-30 104.2 0.1 7.2e-30 103.4 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KFM73142.1 - 3.2e-11 44.0 0.0 7.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KFM73142.1 - 1.9e-05 24.4 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KFM73142.1 - 0.0078 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DDE_3 PF13358.6 KFM73143.1 - 0.00061 19.6 0.0 0.00074 19.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease UPF0767 PF15990.5 KFM73146.1 - 1.3e-29 102.1 0.0 1.5e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 UPF0767 family Phage_holin_5_2 PF16079.5 KFM73146.1 - 0.063 13.6 0.4 0.084 13.2 0.4 1.3 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V CaM-KIIN PF15170.6 KFM73146.1 - 0.076 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor MADF_DNA_bdg PF10545.9 KFM73148.1 - 8.6e-13 48.4 0.0 2e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 KFM73148.1 - 0.0062 16.9 0.2 0.014 15.8 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain BESS PF02944.20 KFM73148.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 BESS motif DAO PF01266.24 KFM73149.1 - 1.1e-50 173.2 0.0 1.3e-50 173.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM73149.1 - 0.0026 18.0 0.0 0.0066 16.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KFM73149.1 - 0.054 12.0 0.0 0.082 11.4 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) 3HCDH_N PF02737.18 KFM73149.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KFM73150.1 - 7.5e-60 203.1 0.1 3e-59 201.1 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFM73150.1 - 6.5e-53 179.7 0.1 8.3e-53 179.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM73150.1 - 8.7e-13 47.9 0.0 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFM73150.1 - 8.4e-10 38.2 0.1 6.8e-05 22.2 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KFM73150.1 - 1.6e-09 37.3 0.0 2.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFM73150.1 - 4.7e-09 35.8 0.5 1.4e-05 24.4 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 KFM73150.1 - 0.012 15.0 0.0 0.052 13.0 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.6 KFM73150.1 - 0.017 15.0 0.0 0.056 13.3 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding NAD_binding_7 PF13241.6 KFM73150.1 - 0.14 12.7 0.0 0.23 11.9 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding LPMO_10 PF03067.15 KFM73151.1 - 1.5e-37 130.2 0.7 2.3e-37 129.5 0.7 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading RT_RNaseH_2 PF17919.1 KFM73152.1 - 6.1e-31 106.4 0.0 1.7e-30 105.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM73152.1 - 3.6e-28 98.6 1.2 7.5e-28 97.6 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM73152.1 - 4.9e-28 97.5 0.0 1.5e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM73152.1 - 7.8e-20 70.7 0.2 2.9e-19 68.9 0.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM73152.1 - 6.5e-18 65.0 0.0 1.7e-15 57.2 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KFM73152.1 - 2.8e-09 37.4 0.0 9.2e-09 35.8 0.0 2.0 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM73152.1 - 1.5e-05 25.6 0.0 3.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM73152.1 - 1.7e-05 25.0 0.0 4.9e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KFM73152.1 - 5.2e-05 23.4 1.0 0.00013 22.1 1.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KFM73152.1 - 8.3e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Arc_C PF18162.1 KFM73152.1 - 0.00017 21.4 3.1 0.00018 21.3 0.6 2.3 2 0 0 2 2 2 1 Arc C-lobe RVT_3 PF13456.6 KFM73152.1 - 0.0026 17.6 0.1 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Asp_protease PF09668.10 KFM73152.1 - 0.0033 17.2 0.1 0.0074 16.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease BH4 PF02180.17 KFM73152.1 - 0.06 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 DDE_3 PF13358.6 KFM73153.1 - 2.9e-16 59.5 0.1 3.1e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73153.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM73154.1 - 1.9e-16 60.1 2.3 4.4e-16 58.9 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73154.1 - 9.4e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Med13_C PF06333.12 KFM73155.1 - 0.11 11.7 5.4 0.12 11.6 5.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF3328 PF11807.8 KFM73155.1 - 0.13 12.0 0.1 0.15 11.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Alpha_GJ PF03229.13 KFM73155.1 - 0.58 10.7 8.2 0.78 10.3 8.2 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J SSP160 PF06933.11 KFM73155.1 - 0.66 8.1 11.8 0.73 8.0 11.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BTB PF00651.31 KFM73156.1 - 4.4e-22 78.4 0.2 1.1e-21 77.2 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain FHIPEP PF00771.20 KFM73156.1 - 0.27 9.6 0.0 0.82 8.1 0.0 1.6 1 1 1 2 2 2 0 FHIPEP family HTH_Tnp_Tc3_2 PF01498.18 KFM73158.1 - 2.2e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73158.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MFAP1 PF06991.11 KFM73159.1 - 1.3e-73 247.5 28.1 1.3e-73 247.5 28.1 2.6 1 1 0 2 2 2 1 Microfibril-associated/Pre-mRNA processing HTH_Tnp_Tc3_2 PF01498.18 KFM73160.1 - 2.2e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73160.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73161.1 - 1.2e-14 54.2 0.8 2.1e-14 53.5 0.8 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73161.1 - 2e-12 47.1 0.0 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73164.1 - 2.6e-16 59.6 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73164.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73164.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73164.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73164.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain C2-set_2 PF08205.12 KFM73165.1 - 2.7e-06 27.3 0.0 3.7e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM73165.1 - 1.9e-05 25.1 0.1 7.2e-05 23.3 0.2 1.8 1 1 1 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFM73165.1 - 0.00032 20.8 0.1 0.0015 18.6 0.1 1.8 1 1 1 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM73165.1 - 0.00073 19.8 0.0 0.0025 18.1 0.0 1.9 1 1 1 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM73165.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain FA_hydroxylase PF04116.13 KFM73166.1 - 4.2e-20 72.5 19.3 4.2e-20 72.5 19.3 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Prokineticin PF06607.11 KFM73167.1 - 0.11 12.9 9.7 0.87 9.9 9.7 2.1 1 1 0 1 1 1 0 Prokineticin DUF1643 PF07799.12 KFM73167.1 - 0.16 12.2 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Fe-S_biosyn PF01521.20 KFM73168.1 - 0.0029 17.8 5.3 0.02 15.1 0.7 2.4 1 1 0 2 2 2 2 Iron-sulphur cluster biosynthesis SUa-2TM PF18179.1 KFM73168.1 - 0.013 14.8 3.3 0.018 14.4 3.0 1.4 1 1 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain CENP-L PF13092.6 KFM73168.1 - 3.3 7.9 5.0 4.9 7.3 5.0 1.3 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 Annexin PF00191.20 KFM73169.1 - 3.8e-95 312.0 5.5 7.3e-26 90.0 0.2 4.0 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFM73169.1 - 0.007 16.2 0.0 6.7 6.7 0.0 3.7 4 0 0 4 4 4 1 Myb DNA-binding like RT_RNaseH PF17917.1 KFM73170.1 - 5e-25 87.8 0.0 2.4e-24 85.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KFM73170.1 - 4.4e-24 84.4 0.2 1.6e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Ald_Xan_dh_C2 PF02738.18 KFM73170.1 - 0.27 9.6 0.0 0.38 9.1 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Annexin PF00191.20 KFM73171.1 - 9.8e-94 307.4 4.2 2.3e-27 94.9 0.0 4.3 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFM73171.1 - 0.12 12.3 0.0 1e+02 2.9 0.0 3.3 4 0 0 4 4 4 0 Myb DNA-binding like MMS22L_C PF14911.6 KFM73172.1 - 9.4e-43 146.7 2.8 1.1e-42 146.5 2.8 1.0 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal MMS22L_N PF14910.6 KFM73173.1 - 1.6e-12 46.7 0.3 1.8e-12 46.6 0.3 1.0 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal TC1 PF15063.6 KFM73173.1 - 0.047 13.6 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Thyroid cancer protein 1 DUF1989 PF09347.10 KFM73173.1 - 0.06 13.0 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) DUF1211 PF06736.11 KFM73174.1 - 0.047 14.1 0.2 0.058 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) BLOC1_2 PF10046.9 KFM73175.1 - 1e-26 93.0 0.9 1.2e-26 92.8 0.9 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1351 PF07083.11 KFM73175.1 - 0.0055 16.5 0.1 0.0061 16.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) Peptidase_M9_N PF08453.10 KFM73175.1 - 0.042 13.6 0.1 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M9 N-terminal DASH_Dad4 PF08650.10 KFM73175.1 - 0.16 12.0 0.8 0.95 9.5 0.8 2.2 1 1 0 1 1 1 0 DASH complex subunit Dad4 XhlA PF10779.9 KFM73175.1 - 0.19 11.9 0.7 4.3 7.6 0.0 2.2 1 1 1 2 2 2 0 Haemolysin XhlA HCO3_cotransp PF00955.21 KFM73177.1 - 4.5e-19 68.7 0.1 5.5e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.22 KFM73177.1 - 1.8e-05 24.6 0.0 2.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.13 KFM73177.1 - 0.00011 22.2 0.1 0.00013 21.9 0.1 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DDE_3 PF13358.6 KFM73178.1 - 3.1e-16 59.5 0.1 3.3e-15 56.1 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73178.1 - 1.5e-10 41.2 1.0 2.9e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Cupin_8 PF13621.6 KFM73180.1 - 1.6e-24 87.0 0.1 2e-24 86.7 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Integrase_H2C2 PF17921.1 KFM73181.1 - 3.2e-13 49.6 0.5 4e-13 49.3 0.5 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM73181.1 - 5e-05 23.4 0.4 8.8e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 H2C2 zinc finger QueC PF06508.13 KFM73181.1 - 0.11 11.9 0.8 0.15 11.5 0.8 1.3 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC FA PF08736.11 KFM73183.1 - 4.9e-10 39.3 11.5 1.1e-09 38.2 11.5 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) Myosin_head PF00063.21 KFM73184.1 - 7.4e-206 685.4 4.1 7.4e-206 685.4 4.1 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin-VI_CBD PF16521.5 KFM73184.1 - 2.9e-42 142.5 0.4 2.8e-41 139.4 0.1 2.6 2 0 0 2 2 2 1 Myosin VI cargo binding domain AAA_22 PF13401.6 KFM73184.1 - 0.005 17.1 0.2 0.21 11.8 0.0 3.5 4 0 0 4 4 4 1 AAA domain Seryl_tRNA_N PF02403.22 KFM73184.1 - 0.0051 17.0 6.3 0.0051 17.0 6.3 2.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain AAA_16 PF13191.6 KFM73184.1 - 0.0053 17.2 1.0 0.031 14.6 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain IQ PF00612.27 KFM73184.1 - 0.024 14.4 0.9 0.067 13.0 0.9 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF413 PF04219.12 KFM73184.1 - 0.025 14.6 1.6 2.3 8.3 1.6 3.3 2 0 0 2 2 2 0 Protein of unknown function, DUF DUF4686 PF15742.5 KFM73184.1 - 0.12 11.4 46.4 0.28 10.3 46.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) ZYG-11_interact PF05884.12 KFM73184.1 - 3.5 7.0 4.8 7 6.0 4.8 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 OmpH PF03938.14 KFM73184.1 - 3.6 7.9 41.2 0.024 15.0 18.3 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Glyco_tranf_2_4 PF13704.6 KFM73185.1 - 3.6e-11 43.4 0.4 1.2e-10 41.7 0.5 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Anp1 PF03452.14 KFM73185.1 - 1.5e-07 31.1 0.1 4e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KFM73185.1 - 0.0037 17.1 0.1 0.86 9.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 SAPS PF04499.15 KFM73186.1 - 1.2e-69 235.4 21.2 4.7e-44 151.0 4.5 3.0 3 1 1 4 4 4 2 SIT4 phosphatase-associated protein AA_permease_2 PF13520.6 KFM73188.1 - 2.7e-18 66.0 11.3 2.9e-18 65.9 11.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM73188.1 - 9.4e-07 27.8 10.0 1.1e-06 27.6 10.0 1.0 1 0 0 1 1 1 1 Amino acid permease DDE_Tnp_1_7 PF13843.6 KFM73190.1 - 1.3e-52 179.3 0.0 1.7e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 YL1 PF05764.13 KFM73190.1 - 0.00082 19.6 1.7 0.0012 19.1 1.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DNA_pol_phi PF04931.13 KFM73190.1 - 2.7 6.0 10.3 4 5.4 8.8 1.9 2 0 0 2 2 2 0 DNA polymerase phi Exo_endo_phos_2 PF14529.6 KFM73191.1 - 5.1e-17 61.8 1.0 2.7e-16 59.5 0.0 2.6 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM73191.1 - 1.7e-06 27.8 0.0 6e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCCH_6 PF18585.1 KFM73191.1 - 0.073 13.0 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 RVT_1 PF00078.27 KFM73192.1 - 2.6e-40 138.3 0.1 4.9e-40 137.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KFM73192.1 - 1.4e-10 41.5 0.2 4.2e-10 40.0 0.2 1.8 1 1 0 1 1 1 1 RNase H SNF PF00209.18 KFM73192.1 - 1.2e-06 27.6 0.1 1.9e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RVT_3 PF13456.6 KFM73192.1 - 7.7e-05 22.5 0.1 0.00016 21.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like HTH_Tnp_Tc3_2 PF01498.18 KFM73193.1 - 7.9e-16 58.1 6.5 1.2e-15 57.5 6.5 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73193.1 - 1.5e-14 54.0 0.0 3.6e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM73193.1 - 0.00061 20.4 1.5 0.00061 20.4 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM73193.1 - 0.0036 17.0 0.4 0.1 12.4 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73193.1 - 0.015 15.4 0.1 0.056 13.6 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM73193.1 - 0.025 14.6 2.4 0.03 14.3 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM73194.1 - 8.4e-16 58.0 6.5 1.4e-15 57.3 6.5 1.3 1 0 0 1 1 1 1 Transposase SNF PF00209.18 KFM73194.1 - 1.2e-11 44.1 1.3 1.7e-11 43.6 1.3 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family HTH_32 PF13565.6 KFM73194.1 - 0.00067 20.2 1.5 0.00067 20.2 1.5 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM73194.1 - 0.0041 16.9 0.3 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73194.1 - 0.02 15.0 0.1 0.061 13.5 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM73194.1 - 0.033 14.2 0.4 0.033 14.2 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix LMBR1 PF04791.16 KFM73194.1 - 0.11 11.3 0.3 0.19 10.6 0.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Transketolase_N PF00456.21 KFM73195.1 - 5.2e-46 157.1 0.0 1.2e-45 156.0 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFM73195.1 - 5.5e-40 136.9 0.0 8.7e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFM73195.1 - 9.2e-30 103.1 0.1 2.5e-29 101.7 0.1 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 KFM73195.1 - 1.4e-08 34.1 0.0 2.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFM73195.1 - 5.7e-08 32.3 0.0 3.8e-05 23.0 0.0 2.7 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 KFM73195.1 - 4.3e-05 22.5 0.0 6.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain TPP_enzyme_C PF02775.21 KFM73195.1 - 4.4e-05 23.3 0.4 0.0016 18.3 0.0 3.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM73196.1 - 6.2e-16 58.4 2.2 6.2e-16 58.4 2.2 2.3 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM73196.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73196.1 - 3.1e-07 30.0 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73196.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73196.1 - 2.8 8.6 15.6 0.13 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73197.1 - 2.2e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73197.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73198.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73198.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73199.1 - 2.2e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73199.1 - 1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease ELO PF01151.18 KFM73200.1 - 2e-56 191.4 21.8 2.5e-56 191.0 21.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CstA PF02554.14 KFM73200.1 - 0.0031 16.5 10.1 0.0031 16.5 10.1 1.3 1 1 0 1 1 1 1 Carbon starvation protein CstA DEK_C PF08766.11 KFM73201.1 - 4.2e-18 65.0 1.4 1.3e-17 63.5 1.4 1.9 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.27 KFM73201.1 - 0.00014 21.5 0.1 0.00038 20.1 0.1 1.8 1 0 0 1 1 1 1 SAP domain SDA1 PF05285.12 KFM73201.1 - 0.0034 16.9 53.9 0.072 12.5 37.3 2.2 2 0 0 2 2 2 2 SDA1 HTH_Tnp_Tc3_2 PF01498.18 KFM73202.1 - 3.3e-14 52.9 1.0 6.2e-14 52.0 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73202.1 - 8.8e-14 51.5 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Penaeidin PF05927.11 KFM73203.1 - 4.4 8.1 9.9 12 6.7 9.9 1.8 1 1 0 1 1 1 0 Penaeidin Cadherin_C_2 PF16492.5 KFM73205.1 - 0.014 16.2 0.2 0.017 15.9 0.2 1.1 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal TrbC PF04956.13 KFM73205.1 - 0.1 12.9 0.0 0.11 12.7 0.0 1.0 1 0 0 1 1 1 0 TrbC/VIRB2 family Penaeidin PF05927.11 KFM73205.1 - 3.1 8.6 13.6 57 4.6 13.6 2.0 1 1 0 1 1 1 0 Penaeidin UAA PF08449.11 KFM73208.1 - 8.2e-64 215.7 29.1 1e-63 215.4 29.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFM73208.1 - 1.9e-05 24.8 27.7 0.00031 20.9 16.8 2.6 2 1 0 2 2 2 2 EamA-like transporter family CPP1-like PF11833.8 KFM73208.1 - 2.5 7.7 12.7 0.035 13.8 1.4 2.7 2 1 1 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fibrinogen_aC PF12160.8 KFM73209.1 - 1.4e-10 40.8 47.6 1 9.3 0.1 12.5 12 0 0 12 12 12 8 Fibrinogen alpha C domain SEEK1 PF15357.6 KFM73209.1 - 0.78 9.9 5.8 40 4.3 0.2 5.8 6 1 1 7 7 7 0 Psoriasis susceptibility 1 candidate 1 CAP160 PF07918.11 KFM73209.1 - 1.9 8.3 5.8 74 3.2 0.0 4.4 5 0 0 5 5 5 0 CAP160 repeat Troponin-I_N PF11636.8 KFM73209.1 - 7.9 6.5 7.2 14 5.7 2.6 3.0 2 0 0 2 2 2 0 Troponin I residues 1-32 Chitin_bind_4 PF00379.23 KFM73210.1 - 5.6e-07 30.0 2.0 1.4e-06 28.7 2.0 1.7 1 0 0 1 1 1 1 Insect cuticle protein LexA_DNA_bind PF01726.16 KFM73210.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 LexA DNA binding domain Chitin_bind_4 PF00379.23 KFM73211.1 - 4.7e-09 36.6 3.4 4.7e-09 36.6 3.4 2.5 3 0 0 3 3 3 1 Insect cuticle protein Mab-21 PF03281.14 KFM73212.1 - 4.9e-38 131.1 2.5 4.9e-38 131.1 2.5 1.6 2 0 0 2 2 2 1 Mab-21 protein CxC5 PF18718.1 KFM73212.1 - 0.06 13.4 2.8 0.11 12.5 2.8 1.5 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Ig_3 PF13927.6 KFM73213.1 - 6e-48 161.4 0.4 1.5e-17 63.9 0.1 5.7 5 1 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFM73213.1 - 1.3e-39 134.2 0.0 1.9e-15 56.7 0.0 5.3 5 0 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.25 KFM73213.1 - 7.7e-34 115.7 0.0 2.7e-10 40.3 0.0 4.8 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 KFM73213.1 - 4.3e-29 100.7 0.4 1.2e-11 44.8 0.2 5.0 5 0 0 5 5 5 3 Immunoglobulin domain fn3 PF00041.21 KFM73213.1 - 1.2e-23 83.3 0.1 3e-12 46.7 0.1 3.3 3 0 0 3 3 3 2 Fibronectin type III domain V-set PF07686.17 KFM73213.1 - 4.7e-13 49.3 9.5 0.23 11.6 0.0 7.6 6 3 3 9 9 9 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM73213.1 - 5.3e-07 29.1 0.0 0.36 10.4 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFM73213.1 - 4.5e-06 26.4 0.7 0.021 14.6 0.1 3.8 3 2 0 3 3 3 2 Adenovirus E3 region protein CR1 C2-set_2 PF08205.12 KFM73213.1 - 3.3e-05 23.9 0.1 0.054 13.6 0.0 3.4 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM73213.1 - 0.00043 20.3 0.1 2.5 8.2 0.0 3.7 3 1 0 3 3 3 2 Izumo-like Immunoglobulin domain UL141 PF16758.5 KFM73213.1 - 0.00058 19.6 0.8 0.99 9.1 0.0 3.9 4 1 0 4 4 4 1 Herpes-like virus membrane glycoprotein UL141 Lep_receptor_Ig PF06328.11 KFM73213.1 - 0.0058 16.6 0.0 2.9 7.9 0.0 3.3 3 0 0 3 3 3 1 Ig-like C2-type domain C1-set PF07654.15 KFM73213.1 - 0.0076 16.6 0.4 0.16 12.4 0.0 3.4 5 0 0 5 5 4 1 Immunoglobulin C1-set domain Cadherin_C_2 PF16492.5 KFM73213.1 - 0.075 13.8 0.0 0.33 11.7 0.0 2.2 2 0 0 2 2 1 0 Cadherin cytoplasmic C-terminal HTH_Tnp_Tc3_2 PF01498.18 KFM73214.1 - 1.7e-11 44.2 0.2 3.4e-11 43.2 0.1 1.5 1 1 0 1 1 1 1 Transposase adh_short_C2 PF13561.6 KFM73216.1 - 0.00011 21.8 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM73216.1 - 0.00044 19.8 0.0 0.00063 19.3 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.25 KFM73217.1 - 1.2e-17 64.0 0.0 1.3e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM73217.1 - 1.8e-07 30.9 0.0 2e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM73217.1 - 3.7e-06 27.0 0.0 4.3e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFM73217.1 - 0.0033 17.3 0.0 0.0034 17.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase_2 PF02350.19 KFM73217.1 - 0.0094 14.8 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase PRMT5 PF05185.16 KFM73217.1 - 0.013 15.3 0.0 0.018 14.9 0.0 1.3 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase ADH_zinc_N PF00107.26 KFM73217.1 - 0.022 14.7 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase G_glu_transpept PF01019.21 KFM73217.1 - 0.042 12.6 0.1 0.13 11.0 0.1 1.6 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase PK_C PF02887.16 KFM73217.1 - 0.05 13.8 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain RrnaAD PF00398.20 KFM73217.1 - 0.091 11.8 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase IFT57 PF10498.9 KFM73218.1 - 2.1e-79 267.1 20.5 2.4e-79 267.0 20.5 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Spc7 PF08317.11 KFM73218.1 - 0.0016 17.4 14.6 0.0016 17.4 14.6 1.7 1 1 0 1 1 1 1 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KFM73218.1 - 0.013 15.1 9.2 0.019 14.6 9.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 KFM73218.1 - 0.017 15.2 15.6 0.28 11.3 1.1 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KFM73218.1 - 0.024 14.7 9.3 0.095 12.7 7.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 KFM73218.1 - 0.025 14.1 12.9 0.051 13.1 12.9 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain SLATT_4 PF18186.1 KFM73218.1 - 0.038 13.6 1.1 0.057 13.1 0.4 1.6 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Sec34 PF04136.15 KFM73218.1 - 0.073 13.0 8.3 0.077 12.9 1.7 2.2 1 1 1 2 2 2 0 Sec34-like family DASH_Dad1 PF08649.10 KFM73218.1 - 0.092 12.9 6.3 2 8.7 0.6 2.9 3 0 0 3 3 2 0 DASH complex subunit Dad1 Seryl_tRNA_N PF02403.22 KFM73218.1 - 0.16 12.2 12.4 0.17 12.2 0.9 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Radical_SAM PF04055.21 KFM73218.1 - 0.16 12.3 0.1 0.4 11.0 0.1 1.6 1 1 0 1 1 1 0 Radical SAM superfamily Phage_Mu_Gam PF07352.12 KFM73218.1 - 0.17 11.8 7.1 0.41 10.5 7.0 1.9 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein WXG100 PF06013.12 KFM73218.1 - 0.18 12.1 4.5 5.7 7.2 2.2 3.0 1 1 1 2 2 2 0 Proteins of 100 residues with WXG MCPsignal PF00015.21 KFM73218.1 - 0.18 11.6 2.9 0.84 9.4 0.7 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.12 KFM73218.1 - 0.19 11.8 5.8 0.42 10.6 3.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HrpB7 PF09486.10 KFM73218.1 - 0.19 12.1 5.9 6.3 7.2 1.3 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Prominin PF05478.11 KFM73218.1 - 0.22 9.4 6.3 0.27 9.1 6.3 1.1 1 0 0 1 1 1 0 Prominin PhaP_Bmeg PF09602.10 KFM73218.1 - 0.24 11.3 11.6 1.4 8.9 8.9 2.7 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Laminin_II PF06009.12 KFM73218.1 - 0.3 11.1 6.6 7.2 6.6 6.4 2.4 1 1 0 1 1 1 0 Laminin Domain II Occludin_ELL PF07303.13 KFM73218.1 - 0.45 11.3 6.5 4.7 8.0 1.9 2.6 1 1 1 2 2 2 0 Occludin homology domain PI3K_P85_iSH2 PF16454.5 KFM73218.1 - 0.57 9.8 16.1 0.21 11.2 1.1 3.1 2 1 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain COG2 PF06148.11 KFM73218.1 - 0.59 10.2 9.5 7.2 6.7 3.3 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2203 PF09969.9 KFM73218.1 - 0.63 10.8 8.2 3 8.6 1.0 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 KFM73218.1 - 0.71 10.2 6.1 95 3.4 5.8 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3347 PF11827.8 KFM73218.1 - 0.76 9.9 7.3 4.1 7.5 0.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) DUF883 PF05957.13 KFM73218.1 - 0.81 10.3 5.0 16 6.1 0.3 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.14 KFM73218.1 - 0.94 9.8 9.4 16 5.8 9.4 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 KFM73218.1 - 1.1 8.4 9.0 4.9 6.3 9.0 1.9 1 1 0 1 1 1 0 TMPIT-like protein Syntaxin_2 PF14523.6 KFM73218.1 - 1.2 9.5 15.0 0.27 11.6 5.9 2.3 2 0 0 2 2 2 0 Syntaxin-like protein YojJ PF10372.9 KFM73218.1 - 1.3 9.1 9.7 8.2 6.6 0.2 3.9 3 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus GAS PF13851.6 KFM73218.1 - 1.5 8.1 19.2 0.11 11.8 13.3 2.1 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4446 PF14584.6 KFM73218.1 - 1.9 8.5 6.0 5.6 6.9 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Fez1 PF06818.15 KFM73218.1 - 1.9 8.9 19.0 0.7 10.3 12.9 2.7 1 1 1 2 2 2 0 Fez1 FapA PF03961.13 KFM73218.1 - 2.2 6.8 11.5 2.2 6.8 9.2 2.0 1 1 0 1 1 1 0 Flagellar Assembly Protein A Nup54 PF13874.6 KFM73218.1 - 3.7 7.7 11.8 7.7 6.6 11.6 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF2703 PF10865.8 KFM73218.1 - 5.2 7.3 7.7 8.6 6.6 0.1 3.3 2 1 1 4 4 3 0 Domain of unknown function (DUF2703) DUF1043 PF06295.12 KFM73218.1 - 6.4 6.8 12.6 16 5.5 1.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) KxDL PF10241.9 KFM73218.1 - 8.1 6.8 9.8 8.1 6.8 0.8 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein Oxysterol_BP PF01237.18 KFM73219.1 - 5.6e-62 209.7 7.0 7.2e-60 202.8 7.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PDCD9 PF07147.12 KFM73219.1 - 0.025 13.8 0.2 0.044 13.0 0.1 1.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) PH PF00169.29 KFM73220.1 - 0.00034 21.1 0.0 0.0016 18.9 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 KFM73220.1 - 0.00084 19.6 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFM73220.1 - 0.0018 18.1 0.1 0.0071 16.2 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 KFM73220.1 - 0.021 15.2 0.0 0.53 10.7 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 KFM73220.1 - 0.091 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Sulfatase_C PF14707.6 KFM73220.1 - 0.11 13.3 0.1 1.3 9.8 0.0 2.3 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase RUN PF02759.19 KFM73221.1 - 3.6e-25 88.5 0.0 1.1e-24 87.0 0.0 1.8 1 0 0 1 1 1 1 RUN domain DUF3964 PF13107.6 KFM73221.1 - 0.054 13.9 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) Mycoplasma_p37 PF06646.11 KFM73221.1 - 0.11 11.7 0.8 0.19 10.9 0.4 1.6 2 0 0 2 2 2 0 High affinity transport system protein p37 TMEM192 PF14802.6 KFM73221.1 - 3.1 6.8 7.4 11 5.1 3.5 2.2 1 1 1 2 2 2 0 TMEM192 family DUF2120 PF09893.9 KFM73221.1 - 3.2 7.9 7.4 3 8.0 2.6 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) YlqD PF11068.8 KFM73221.1 - 4.4 7.7 14.2 8 6.8 8.9 2.7 2 0 0 2 2 2 0 YlqD protein CemA PF03040.14 KFM73221.1 - 5.8 6.8 6.4 3.8 7.4 2.8 2.1 1 1 1 2 2 2 0 CemA family HTH_Tnp_Tc3_2 PF01498.18 KFM73222.1 - 3.1e-18 65.8 3.9 3.9e-18 65.5 1.6 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73222.1 - 2.5e-16 59.7 0.0 1.5e-15 57.2 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM73222.1 - 1.3e-05 25.7 4.4 1.4e-05 25.7 2.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM73222.1 - 0.00025 20.8 0.6 0.012 15.4 0.0 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM73222.1 - 0.0019 18.2 0.6 0.033 14.2 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM73222.1 - 0.0026 17.9 0.8 0.64 10.2 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM73222.1 - 0.0078 16.2 1.5 0.051 13.6 0.2 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_17 PF12728.7 KFM73222.1 - 0.0093 16.1 0.1 1.4 9.1 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM73222.1 - 0.025 14.7 2.4 8 6.6 0.0 3.3 2 1 1 3 3 3 0 Helix-turn-helix domain of resolvase MarR_2 PF12802.7 KFM73222.1 - 0.067 13.1 1.4 0.19 11.7 0.1 2.3 3 0 0 3 3 3 0 MarR family HTH_Tnp_Tc3_2 PF01498.18 KFM73223.1 - 4.9e-16 58.7 3.5 5.6e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73223.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73223.1 - 5.2e-07 29.3 1.4 6.9e-07 28.9 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73223.1 - 0.0026 17.5 0.6 0.0074 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73224.1 - 4.2e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73224.1 - 1.1e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73224.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73224.1 - 0.0025 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73224.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Beta-TrCP_D PF12125.8 KFM73225.1 - 1.6e-17 63.1 2.8 2.8e-17 62.3 2.8 1.4 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.7 KFM73225.1 - 8.7e-11 41.5 0.2 2.3e-10 40.2 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFM73225.1 - 3.7e-08 33.0 0.1 8.2e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KFM73225.1 - 0.00068 19.2 0.7 0.0022 17.5 0.7 1.9 1 1 0 1 1 1 1 F-box RUN PF02759.19 KFM73226.1 - 3.2e-20 72.5 0.0 2.8e-19 69.4 0.0 2.5 1 1 0 1 1 1 1 RUN domain rve PF00665.26 KFM73226.1 - 1.7e-17 63.7 0.0 5.1e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_48 PF17906.1 KFM73226.1 - 1.8e-05 24.7 0.0 4.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 HTH domain in Mos1 transposase TRAF_BIRC3_bd PF16673.5 KFM73226.1 - 0.016 15.0 4.9 0.055 13.3 4.9 1.9 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain UPF0242 PF06785.11 KFM73226.1 - 0.31 11.1 6.2 0.68 10.0 6.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ribosomal_L16 PF00252.18 KFM73227.1 - 1.9e-44 150.8 0.1 2.2e-44 150.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Piwi PF02171.17 KFM73228.1 - 6.6e-83 278.4 0.1 1.5e-82 277.3 0.0 1.6 2 0 0 2 2 2 1 Piwi domain ArgoN PF16486.5 KFM73228.1 - 8.6e-15 55.6 0.3 2.1e-14 54.3 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KFM73228.1 - 9.1e-12 45.0 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KFM73228.1 - 1.3e-09 38.2 0.0 3.6e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL1 PF08699.10 KFM73228.1 - 2.7e-09 36.6 0.3 6.8e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFM73228.1 - 6.9e-06 26.3 0.0 2.2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain FMN_dh PF01070.18 KFM73229.1 - 1.2e-92 310.7 0.0 6e-57 193.2 0.1 2.7 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KFM73229.1 - 1.8e-07 30.5 2.7 8.7e-07 28.3 0.1 2.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFM73229.1 - 1.6e-05 24.2 0.0 1.6e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase MspA PF09203.11 KFM73229.1 - 0.015 15.1 19.8 0.31 10.9 5.9 4.4 2 2 1 3 3 3 0 MspA Ntox6 PF15544.6 KFM73229.1 - 0.18 11.3 0.0 0.18 11.3 0.0 2.6 3 0 0 3 3 3 0 Bacterial toxin 6 OMP_b-brl PF13505.6 KFM73229.1 - 0.73 9.9 13.8 0.16 12.1 5.1 3.6 3 1 0 3 3 3 0 Outer membrane protein beta-barrel domain FMN_dh PF01070.18 KFM73230.1 - 3e-98 329.1 0.0 3.7e-98 328.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFM73230.1 - 8.1e-06 25.1 1.4 2.5e-05 23.4 0.9 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFM73230.1 - 4.8e-05 22.7 0.2 7e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KFM73230.1 - 0.0098 15.3 1.1 0.016 14.6 1.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KFM73230.1 - 0.01 15.3 0.1 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.14 KFM73230.1 - 0.04 13.2 0.3 1.4 8.2 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Dus PF01207.17 KFM73230.1 - 0.17 11.0 0.5 3 6.8 0.2 2.3 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) Sec3_C PF09763.9 KFM73231.1 - 0.36 9.1 1.4 0.37 9.1 1.4 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 Presenilin PF01080.17 KFM73231.1 - 0.94 8.2 3.6 1.1 8.0 3.6 1.2 1 0 0 1 1 1 0 Presenilin DUF2981 PF11200.8 KFM73231.1 - 1.2 8.8 5.6 1.4 8.6 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF908 PF06012.12 KFM73231.1 - 1.4 8.3 5.1 1.4 8.2 5.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SPX PF03105.19 KFM73231.1 - 4.9 7.0 11.4 5.2 6.9 11.4 1.0 1 0 0 1 1 1 0 SPX domain SAPS PF04499.15 KFM73231.1 - 9 5.0 7.8 9.6 4.9 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1180 PF06679.12 KFM73233.1 - 0.012 16.0 5.5 0.017 15.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SpoIIIAH PF12685.7 KFM73233.1 - 0.037 13.9 9.3 0.045 13.6 9.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein tRNA_anti-like PF12869.7 KFM73233.1 - 0.22 11.2 1.8 2.7 7.6 1.8 2.0 1 1 0 1 1 1 0 tRNA_anti-like Presenilin PF01080.17 KFM73233.1 - 0.24 10.1 2.0 0.28 9.9 2.0 1.1 1 0 0 1 1 1 0 Presenilin EVI2A PF05399.11 KFM73233.1 - 0.55 9.8 8.4 0.67 9.5 8.4 1.0 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Ndc1_Nup PF09531.10 KFM73233.1 - 2.2 6.9 7.0 2.5 6.7 7.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.15 KFM73233.1 - 2.2 6.9 7.5 2.3 6.9 7.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HTH_Tnp_Tc3_2 PF01498.18 KFM73235.1 - 2.2e-16 59.9 2.2 4e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73235.1 - 8.3e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73237.1 - 4.4e-16 58.9 3.5 6.2e-16 58.4 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73237.1 - 1.4e-13 50.9 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73237.1 - 2.6e-07 30.3 1.6 7.5e-07 28.8 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73237.1 - 0.0022 17.8 0.6 0.0081 15.9 0.6 2.1 1 0 0 1 1 1 1 Homeodomain-like domain Pkinase PF00069.25 KFM73238.1 - 3.5e-27 95.4 0.0 4.4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73238.1 - 7.3e-15 54.9 0.0 9.1e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM73238.1 - 5.3e-11 41.9 0.0 6.2e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KFM73238.1 - 0.043 12.8 0.1 0.065 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KFM73238.1 - 0.047 13.6 0.0 0.95 9.3 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM73238.1 - 0.15 11.4 0.7 0.19 11.1 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HATPase_c_3 PF13589.6 KFM73239.1 - 4.3e-12 46.0 0.0 5.5e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFM73239.1 - 3.5e-08 33.9 0.0 4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NTNH_C PF08470.10 KFM73239.1 - 0.17 11.7 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal Mlh1_C PF16413.5 KFM73240.1 - 3.2e-83 279.2 0.8 4.1e-83 278.9 0.1 1.5 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KFM73240.1 - 1.4e-34 118.3 0.6 2.3e-34 117.6 0.6 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Chitin_bind_4 PF00379.23 KFM73243.1 - 1.7e-09 38.1 3.2 3e-09 37.3 3.2 1.4 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM73244.1 - 6e-10 39.5 3.9 6e-10 39.5 3.9 2.3 2 0 0 2 2 2 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM73245.1 - 7.8e-10 39.1 3.5 1.5e-09 38.2 3.5 1.5 1 0 0 1 1 1 1 Insect cuticle protein Peptidase_M7 PF02031.16 KFM73245.1 - 0.0047 17.1 1.3 0.0074 16.4 1.3 1.4 1 1 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Cuticle_3 PF11018.8 KFM73245.1 - 0.35 11.1 32.8 0.035 14.3 28.3 1.6 2 0 0 2 2 2 0 Pupal cuticle protein C1 DUF3432 PF11914.8 KFM73245.1 - 2.1 8.6 15.5 0.29 11.4 11.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) 2OG-FeII_Oxy_2 PF13532.6 KFM73246.1 - 2.5e-19 70.2 0.0 3.1e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Chitin_bind_4 PF00379.23 KFM73247.1 - 2.2e-08 34.5 3.3 4.5e-08 33.5 3.3 1.5 1 0 0 1 1 1 1 Insect cuticle protein Cuticle_3 PF11018.8 KFM73247.1 - 0.00031 21.0 29.8 0.00031 21.0 29.8 1.7 2 0 0 2 2 2 1 Pupal cuticle protein C1 Cornifin PF02389.15 KFM73247.1 - 0.13 12.5 4.9 0.17 12.0 4.9 1.2 1 0 0 1 1 1 0 Cornifin (SPRR) family Chitin_bind_4 PF00379.23 KFM73248.1 - 1.1e-09 38.7 3.1 2.2e-09 37.7 3.1 1.5 1 0 0 1 1 1 1 Insect cuticle protein Cuticle_3 PF11018.8 KFM73248.1 - 0.95 9.7 26.7 0.19 11.9 22.7 1.8 2 0 0 2 2 2 0 Pupal cuticle protein C1 DUF3432 PF11914.8 KFM73248.1 - 1.8 8.8 12.5 0.21 11.8 8.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) Chitin_bind_4 PF00379.23 KFM73249.1 - 1.2e-10 41.8 0.3 2e-10 41.1 0.3 1.4 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM73250.1 - 4.7e-08 33.4 2.5 9.2e-08 32.5 1.7 1.8 2 0 0 2 2 2 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM73251.1 - 2.1e-07 31.4 7.2 2.1e-07 31.4 7.2 2.5 2 0 0 2 2 2 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM73252.1 - 3.8e-08 33.7 2.3 8.5e-08 32.6 2.3 1.6 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM73253.1 - 1.4e-08 35.1 3.1 3.3e-08 33.9 3.1 1.7 1 0 0 1 1 1 1 Insect cuticle protein HTH_Tnp_Tc3_2 PF01498.18 KFM73254.1 - 2.3e-16 59.8 1.7 2.3e-16 59.8 1.7 1.7 2 0 0 2 2 2 1 Transposase MarR_2 PF12802.7 KFM73254.1 - 2.2e-05 24.2 0.2 0.001 18.9 0.0 2.6 1 1 1 2 2 2 1 MarR family HTH_23 PF13384.6 KFM73254.1 - 6.6e-05 22.6 1.7 0.00054 19.7 0.0 2.8 3 1 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73254.1 - 0.00016 21.7 3.0 0.00059 19.9 0.2 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.18 KFM73254.1 - 0.00023 21.1 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_3 PF01381.22 KFM73254.1 - 0.00045 20.2 0.3 0.014 15.5 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix HTH_32 PF13565.6 KFM73254.1 - 0.00085 19.9 10.5 0.0017 18.9 3.5 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM73254.1 - 0.0012 18.8 0.4 0.005 16.8 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM73254.1 - 0.0031 17.1 0.8 0.044 13.4 0.0 3.0 3 1 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 KFM73254.1 - 0.016 15.6 0.3 6.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.16 KFM73254.1 - 0.028 13.9 0.1 0.028 13.9 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_20 PF12840.7 KFM73254.1 - 0.043 13.9 0.1 5.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_8 PF02954.19 KFM73254.1 - 0.05 13.4 0.1 3.7 7.4 0.4 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family TrmB PF01978.19 KFM73254.1 - 0.19 11.7 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_31 PF13560.6 KFM73254.1 - 0.2 12.0 0.2 0.2 12.0 0.2 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM73256.1 - 4.8e-16 58.8 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73256.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73256.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73256.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73256.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DUF2236 PF09995.9 KFM73258.1 - 0.029 14.6 0.4 0.03 14.5 0.4 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) Amnionless PF14828.6 KFM73258.1 - 0.049 12.5 1.5 0.051 12.4 1.5 1.0 1 0 0 1 1 1 0 Amnionless Orf78 PF06024.12 KFM73258.1 - 0.058 13.7 0.5 0.064 13.6 0.5 1.2 1 0 0 1 1 1 0 Orf78 (ac78) EssA PF10661.9 KFM73258.1 - 0.097 12.5 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA TMEM154 PF15102.6 KFM73258.1 - 0.13 12.1 0.2 0.14 12.1 0.2 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF3619 PF12279.8 KFM73258.1 - 0.22 11.8 1.3 0.25 11.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Insulin_TMD PF17870.1 KFM73258.1 - 4 7.6 7.4 0.25 11.5 2.6 1.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Lig_chan PF00060.26 KFM73260.1 - 8.5e-54 181.4 0.5 1.2e-53 181.0 0.5 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFM73260.1 - 3.3e-43 146.5 0.2 5.5e-43 145.8 0.2 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM73260.1 - 6e-23 81.4 0.0 8.8e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFM73260.1 - 0.00068 18.8 0.1 0.001 18.3 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Cellulase PF00150.18 KFM73260.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Pyr_redox_2 PF07992.14 KFM73261.1 - 1.3e-14 54.2 0.0 3.9e-14 52.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM73261.1 - 0.0034 16.7 0.0 0.029 13.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM73261.1 - 0.019 15.5 0.0 0.04 14.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM73261.1 - 0.056 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Glu_synthase PF01645.17 KFM73262.1 - 2.2e-136 454.8 0.4 3.1e-136 454.4 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GXGXG PF01493.19 KFM73262.1 - 8e-78 260.4 1.9 1.3e-77 259.7 1.9 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 KFM73262.1 - 8.8e-21 73.8 0.4 2.2e-20 72.5 0.4 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KFM73262.1 - 1e-07 32.0 0.4 1e-07 32.0 0.4 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFM73262.1 - 1.2e-05 24.2 0.1 2.5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KFM73262.1 - 7.9e-05 21.9 0.5 0.00022 20.5 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFM73262.1 - 0.00019 20.8 0.1 0.00031 20.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFM73262.1 - 0.00031 20.2 0.1 0.00045 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KFM73262.1 - 0.00057 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KFM73262.1 - 0.0013 18.1 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFM73262.1 - 0.0041 16.8 0.1 0.0067 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFM73262.1 - 0.0084 15.4 0.5 0.017 14.4 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM73262.1 - 0.0091 15.3 0.3 0.024 13.9 0.3 1.6 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KFM73262.1 - 0.013 14.6 0.5 0.02 14.0 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KFM73262.1 - 0.057 14.0 0.6 0.16 12.6 0.1 2.1 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FMN_dh PF01070.18 KFM73262.1 - 0.1 11.6 0.2 0.31 10.0 0.2 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lycopene_cycl PF05834.12 KFM73262.1 - 0.23 10.4 0.1 0.36 9.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Glu_syn_central PF04898.14 KFM73263.1 - 7.8e-103 343.8 0.0 9.1e-103 343.6 0.0 1.0 1 0 0 1 1 1 1 Glutamate synthase central domain GATase_2 PF00310.21 KFM73264.1 - 1.7e-73 247.7 0.1 2e-73 247.5 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KFM73265.1 - 8.1e-08 31.4 0.9 8.5e-08 31.3 0.9 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF5398 PF17376.2 KFM73265.1 - 0.047 14.3 0.1 0.057 14.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5398) BAP PF06639.11 KFM73265.1 - 0.072 13.4 0.3 0.08 13.3 0.3 1.2 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) MFS_1 PF07690.16 KFM73267.1 - 3.2e-40 138.2 12.0 3.1e-26 92.2 6.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM73267.1 - 0.0011 17.9 8.3 0.0011 17.9 8.3 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KFM73267.1 - 0.0043 16.0 25.7 0.07 12.0 9.8 3.1 2 2 1 3 3 3 3 MFS_1 like family DDE_3 PF13358.6 KFM73268.1 - 7.9e-05 22.4 0.0 9.7e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.18 KFM73268.1 - 0.15 11.9 0.0 0.49 10.3 0.0 1.8 1 1 0 1 1 1 0 Transposase (partial DDE domain) TPR_1 PF00515.28 KFM73270.1 - 0.019 14.7 2.3 0.61 10.0 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM73270.1 - 0.049 13.8 3.7 0.56 10.4 0.6 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat kleA_kleC PF17383.2 KFM73270.1 - 0.081 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Arb2 PF09757.9 KFM73270.1 - 0.2 10.7 0.0 0.23 10.6 0.0 1.0 1 0 0 1 1 1 0 Arb2 domain SET PF00856.28 KFM73274.1 - 4.9e-08 33.6 0.4 4.9e-08 33.6 0.4 2.0 2 1 0 2 2 2 1 SET domain TPR_12 PF13424.6 KFM73274.1 - 0.0098 16.2 0.8 0.028 14.7 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Globin PF00042.22 KFM73274.1 - 0.065 13.8 0.2 0.17 12.4 0.1 1.7 2 0 0 2 2 2 0 Globin Hormone_recep PF00104.30 KFM73275.1 - 3.7e-19 69.1 1.4 2.1e-18 66.6 1.4 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ldl_recept_a PF00057.18 KFM73277.1 - 1.3e-25 89.3 43.9 2.3e-11 43.7 12.1 3.2 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFM73279.1 - 1.1e-25 89.9 0.1 1.4e-06 28.7 0.1 5.6 6 0 0 6 6 6 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFM73279.1 - 3.9e-07 30.2 2.6 6.7e-07 29.5 2.6 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site SGL PF08450.12 KFM73279.1 - 4.9e-07 29.6 0.2 0.00012 21.7 0.0 2.5 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KFM73279.1 - 7.2e-07 29.3 1.9 0.25 11.6 0.7 4.2 3 1 1 4 4 4 2 Arylesterase cEGF PF12662.7 KFM73279.1 - 0.0035 17.3 0.2 0.0081 16.1 0.2 1.6 1 0 0 1 1 1 1 Complement Clr-like EGF-like DUF2963 PF11178.8 KFM73279.1 - 0.13 12.0 1.8 0.25 11.1 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) FXa_inhibition PF14670.6 KFM73280.1 - 0.00033 20.9 22.1 0.0025 18.0 10.6 2.5 1 1 1 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFM73280.1 - 0.00041 20.2 1.0 0.00041 20.2 1.0 3.1 3 1 0 3 3 3 1 Complement Clr-like EGF-like EGF PF00008.27 KFM73280.1 - 0.0012 19.1 24.6 0.021 15.1 6.6 3.0 1 1 0 2 2 2 2 EGF-like domain EGF_MSP1_1 PF12946.7 KFM73280.1 - 0.33 11.0 15.7 1.9 8.6 13.5 2.7 1 1 0 1 1 1 0 MSP1 EGF domain 1 EGF_3 PF12947.7 KFM73280.1 - 4.6 7.5 25.5 0.11 12.7 11.7 3.0 2 2 0 2 2 2 0 EGF domain EGF_CA PF07645.15 KFM73280.1 - 6.3 7.1 24.8 0.06 13.6 14.8 2.6 1 1 1 2 2 2 0 Calcium-binding EGF domain zf-H2C2_2 PF13465.6 KFM73281.1 - 6.7e-132 424.6 122.5 6.8e-09 35.8 0.3 19.1 19 0 0 19 19 19 18 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73281.1 - 6.7e-88 284.5 151.6 1.1e-06 28.7 0.8 18.1 18 0 0 18 18 18 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73281.1 - 2.8e-59 192.6 152.5 0.00019 22.0 0.6 18.3 18 0 0 18 18 18 18 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM73281.1 - 5e-27 93.3 120.3 0.00046 20.1 0.3 18.7 18 0 0 18 18 18 14 C2H2-type zinc finger zf-met PF12874.7 KFM73281.1 - 9.1e-27 92.6 129.1 0.012 16.0 0.7 18.4 18 0 0 18 18 18 15 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM73281.1 - 2.2e-14 53.3 97.3 0.11 12.8 0.2 18.1 18 0 0 18 18 18 8 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM73281.1 - 2.7e-12 46.5 66.7 0.27 11.3 0.0 17.4 10 5 8 18 18 18 6 Sec23/Sec24 zinc finger BolA PF01722.18 KFM73281.1 - 8.3e-10 38.8 18.4 0.75 10.1 0.1 11.6 1 1 9 10 10 10 2 BolA-like protein zf-H2C2_5 PF13909.6 KFM73281.1 - 6.7e-08 32.1 114.8 0.19 11.5 1.1 18.3 18 0 0 18 18 18 11 C2H2-type zinc-finger domain DUF4825 PF16107.5 KFM73281.1 - 1.1e-07 31.8 0.0 12 6.1 0.0 7.8 4 2 5 9 9 9 0 Domain of unknown function (DUF4825) Tox-HNH-HHH PF15637.6 KFM73281.1 - 8.7e-05 22.6 0.7 11 6.2 0.0 6.2 1 1 7 10 10 10 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_11 PF16622.5 KFM73281.1 - 0.00017 21.3 113.2 0.077 12.8 0.7 16.9 18 0 0 18 18 18 8 zinc-finger C2H2-type Yop-YscD_ppl PF16693.5 KFM73281.1 - 0.016 14.6 0.0 13 5.1 0.0 3.6 4 0 0 4 4 4 0 Inner membrane component of T3SS, periplasmic domain zf-MYST PF17772.1 KFM73281.1 - 0.066 12.8 99.0 0.65 9.7 0.2 16.8 7 4 11 18 18 18 0 MYST family zinc finger domain GATase_2 PF00310.21 KFM73281.1 - 0.14 10.8 0.9 0.75 8.4 0.1 2.4 2 1 1 3 3 3 0 Glutamine amidotransferases class-II FAM110_N PF14161.6 KFM73281.1 - 0.44 10.8 1.4 12 6.2 0.0 3.8 5 1 0 5 5 5 0 Centrosome-associated N terminus Tnp_P_element PF12017.8 KFM73282.1 - 2e-05 24.1 0.0 2.4e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Transposase protein zf-H2C2_2 PF13465.6 KFM73283.1 - 2.7e-70 229.9 39.8 1.4e-09 38.0 1.1 8.1 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73283.1 - 1.9e-39 131.9 59.1 1.1e-06 28.7 1.0 8.5 9 0 0 9 9 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73283.1 - 2e-30 102.8 60.1 0.00011 22.7 0.8 8.8 9 0 0 9 9 9 7 C2H2-type zinc finger zf-met PF12874.7 KFM73283.1 - 1.7e-16 60.0 65.8 0.0092 16.3 1.3 8.6 9 0 0 9 9 9 7 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM73283.1 - 1.7e-13 50.0 37.5 0.031 14.0 0.6 8.4 8 0 0 8 8 8 7 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM73283.1 - 6.8e-11 41.7 38.4 0.036 13.8 0.1 8.3 8 0 0 8 8 8 5 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM73283.1 - 5.1e-10 39.2 24.5 0.27 11.3 0.5 8.0 6 2 2 8 8 8 2 Sec23/Sec24 zinc finger BolA PF01722.18 KFM73283.1 - 5.3e-10 39.4 3.3 0.38 11.0 0.0 5.5 1 1 3 4 4 4 3 BolA-like protein zf-C2H2_jaz PF12171.8 KFM73283.1 - 8.7e-08 32.3 45.1 0.036 14.4 0.1 8.2 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM73283.1 - 1.4e-06 28.1 54.6 0.19 11.8 0.4 8.2 8 0 0 8 8 7 6 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM73283.1 - 6.8e-05 22.6 23.1 1.4 8.9 0.1 7.8 7 0 0 7 7 7 1 zinc-finger of a C2HC-type Tox-HNH-HHH PF15637.6 KFM73283.1 - 8.3e-05 22.7 0.3 5.2 7.3 0.0 3.8 1 1 3 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif Zf_RING PF16744.5 KFM73283.1 - 0.00014 21.9 34.7 1.9 8.7 0.4 7.2 1 1 5 6 6 6 2 KIAA1045 RING finger zf-C2H2_9 PF16293.5 KFM73283.1 - 0.00019 21.2 27.2 2.6 8.0 0.2 7.1 2 2 5 7 7 7 3 C2H2 type zinc-finger (1 copy) Suc_Fer-like PF06999.12 KFM73283.1 - 0.00025 21.0 1.0 0.16 11.9 0.2 4.1 1 1 3 4 4 4 1 Sucrase/ferredoxin-like C1_1 PF00130.22 KFM73283.1 - 0.0044 16.9 38.6 0.071 13.0 3.4 5.9 1 1 4 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFM73283.1 - 0.0072 15.9 29.5 4.2 7.0 0.1 7.4 7 0 0 7 7 7 1 Ubiquitin-Binding Zinc Finger TRAF6_Z2 PF18048.1 KFM73283.1 - 0.011 15.8 40.1 0.077 13.1 0.6 7.9 8 0 0 8 8 8 0 TNF receptor-associated factor 6 zinc finger 2 GAGA PF09237.11 KFM73283.1 - 0.025 14.4 11.9 7.8 6.4 0.0 5.9 1 1 6 7 7 7 0 GAGA factor zf-C2H2_2 PF12756.7 KFM73283.1 - 0.028 14.8 41.9 3.4 8.1 0.6 7.0 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM73283.1 - 0.043 13.4 33.4 1.3 8.7 0.5 7.1 1 1 6 7 7 7 0 MYST family zinc finger domain FYVE PF01363.21 KFM73283.1 - 0.048 13.8 36.3 0.35 11.0 10.4 4.3 1 1 3 4 4 4 0 FYVE zinc finger DUF5511 PF17630.2 KFM73283.1 - 0.07 13.3 2.2 7.6 6.8 0.1 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5511) zinc_ribbon_15 PF17032.5 KFM73283.1 - 0.15 12.9 30.0 1.8 9.4 1.2 4.1 1 1 3 4 4 4 0 zinc-ribbon family XPA_N PF01286.18 KFM73283.1 - 0.16 12.0 28.0 1.3 9.2 0.1 7.0 7 0 0 7 7 7 0 XPA protein N-terminal ADK_lid PF05191.14 KFM73283.1 - 0.2 11.7 25.6 2 8.5 1.4 5.1 3 3 1 4 4 4 0 Adenylate kinase, active site lid Amidohydro_1 PF01979.20 KFM73283.1 - 0.28 10.5 2.1 19 4.5 0.0 3.6 1 1 4 5 5 5 0 Amidohydrolase family C1_2 PF03107.16 KFM73283.1 - 0.83 10.0 46.5 2 8.8 5.7 7.3 2 2 4 6 6 6 0 C1 domain zf-FPG_IleRS PF06827.14 KFM73283.1 - 1.5 8.8 18.9 23 5.0 0.0 6.3 6 1 1 7 7 6 0 Zinc finger found in FPG and IleRS PHD PF00628.29 KFM73283.1 - 1.5 8.7 36.4 0.15 12.0 5.1 5.1 5 1 0 5 5 5 0 PHD-finger DUF2256 PF10013.9 KFM73283.1 - 3.2 8.0 29.1 23 5.2 0.5 7.1 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_4 PF07975.12 KFM73283.1 - 4.1 7.7 37.0 1.5 9.1 1.4 5.6 2 1 3 6 6 6 0 TFIIH C1-like domain A2L_zn_ribbon PF08792.10 KFM73283.1 - 5.1 6.9 35.5 3.6 7.4 0.1 7.6 8 0 0 8 8 8 0 A2L zinc ribbon domain Viral_cys_rich PF08008.12 KFM73283.1 - 6.4 6.9 16.3 3.4 7.8 0.4 4.1 4 1 1 5 5 5 0 Viral cysteine rich Sclerostin PF05463.11 KFM73284.1 - 0.017 14.9 0.2 0.019 14.7 0.2 1.0 1 0 0 1 1 1 0 Sclerostin (SOST) MADF_DNA_bdg PF10545.9 KFM73285.1 - 1.6e-06 28.3 0.3 9.1e-05 22.7 0.2 2.3 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 KFM73285.1 - 0.044 14.2 0.4 0.11 12.8 0.2 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 KFM73286.1 - 4.4e-12 46.0 0.0 6.9e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 KFM73287.1 - 3e-92 299.3 79.4 1.3e-09 38.0 2.2 12.9 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73287.1 - 7.3e-57 186.8 105.1 2.1e-06 27.9 1.0 13.9 14 0 0 14 14 14 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73287.1 - 1.8e-40 134.1 99.5 0.00053 20.6 1.3 13.9 14 0 0 14 14 14 10 C2H2-type zinc finger zf-met PF12874.7 KFM73287.1 - 5.7e-25 86.9 85.3 0.0083 16.5 1.4 12.3 12 0 0 12 12 12 11 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM73287.1 - 1.7e-11 43.6 74.9 0.019 14.7 1.0 12.6 14 0 0 14 14 13 6 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM73287.1 - 3.7e-11 43.0 61.7 0.0021 18.3 0.4 11.8 12 0 0 12 12 11 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM73287.1 - 2e-10 40.4 84.4 0.006 16.6 1.1 12.8 12 1 0 12 12 12 6 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM73287.1 - 3.1e-10 39.9 38.2 1.2 9.2 0.1 11.4 11 1 1 12 12 12 6 Sec23/Sec24 zinc finger BolA PF01722.18 KFM73287.1 - 1.6e-08 34.7 13.6 5.1 7.5 0.0 8.2 1 1 8 9 9 9 2 BolA-like protein zf-H2C2_5 PF13909.6 KFM73287.1 - 1.1e-07 31.4 70.6 0.091 12.5 0.1 12.8 13 0 0 13 13 13 7 C2H2-type zinc-finger domain Tox-HNH-HHH PF15637.6 KFM73287.1 - 8.8e-06 25.8 0.7 2.5 8.3 0.0 4.5 2 2 0 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif GAGA PF09237.11 KFM73287.1 - 4.6e-05 23.1 27.8 0.72 9.7 0.1 9.2 2 2 9 11 11 11 3 GAGA factor zf-C2H2_9 PF16293.5 KFM73287.1 - 0.008 16.0 45.2 6.7 6.6 1.1 10.7 3 1 8 11 11 11 3 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 KFM73287.1 - 0.078 13.1 57.2 0.64 10.2 0.3 11.2 1 1 9 11 11 11 0 KIAA1045 RING finger zinc_ribbon_15 PF17032.5 KFM73287.1 - 0.24 12.2 47.1 3.9 8.3 1.5 6.1 1 1 3 6 6 6 0 zinc-ribbon family Baculo_IE-1 PF05290.11 KFM73287.1 - 0.62 10.0 48.6 0.18 11.7 4.0 8.8 1 1 4 5 5 5 0 Baculovirus immediate-early protein (IE-0) zf-DBF PF07535.12 KFM73287.1 - 2.4 8.3 56.2 7.6 6.7 0.3 11.0 11 0 0 11 11 11 0 DBF zinc finger zf-C2HC_2 PF13913.6 KFM73287.1 - 3 7.8 46.4 0.94 9.5 0.1 10.9 11 0 0 11 11 11 0 zinc-finger of a C2HC-type Aa_trans PF01490.18 KFM73288.1 - 1.9e-55 188.2 11.1 2.3e-55 188.0 11.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 KFM73288.1 - 0.0038 16.1 0.3 0.0038 16.1 0.3 2.6 1 1 1 3 3 3 1 Spore germination protein Ytp1 PF10355.9 KFM73288.1 - 0.055 12.7 1.1 0.37 10.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (Ytp1) DUF4269 PF14091.6 KFM73289.1 - 0.11 12.7 5.3 2.7 8.2 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4269) TMC PF07810.13 KFM73290.1 - 4.2e-38 130.4 2.1 4.2e-38 130.4 2.1 3.4 3 1 0 3 3 3 1 TMC domain SAP130_C PF16014.5 KFM73291.1 - 3.9e-39 134.9 7.9 4.1e-38 131.5 0.6 7.1 3 2 5 8 8 8 3 Histone deacetylase complex subunit SAP130 C-terminus DUF1319 PF07028.11 KFM73291.1 - 0.054 13.7 0.9 0.12 12.6 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) MLVIN_C PF18697.1 KFM73295.1 - 0.058 13.5 0.1 0.094 12.8 0.1 1.4 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_Tnp_1_7 PF13843.6 KFM73296.1 - 2e-07 30.7 0.0 2.6e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 HTH_48 PF17906.1 KFM73297.1 - 1.1e-07 31.9 0.4 2.5e-07 30.7 0.4 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM73297.1 - 7.6e-05 23.2 0.0 0.00049 20.7 0.0 2.2 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73297.1 - 0.0086 16.3 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 Transposase HTH_24 PF13412.6 KFM73297.1 - 0.021 14.4 0.7 0.066 12.8 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_9 PF08221.11 KFM73297.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DDE_3 PF13358.6 KFM73299.1 - 7.6e-15 54.9 0.0 1.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73299.1 - 2.9e-07 30.6 0.1 6.9e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM73300.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73300.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73300.1 - 1.7e-07 30.9 1.2 6.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73300.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73300.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DnaJ PF00226.31 KFM73301.1 - 2.6e-20 72.3 0.8 2.6e-20 72.3 0.8 2.0 2 0 0 2 2 2 1 DnaJ domain DUF1266 PF06889.11 KFM73301.1 - 0.0041 17.2 1.9 0.0045 17.1 0.3 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1266) Indigoidine_A PF04227.12 KFM73301.1 - 0.085 12.2 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Indigoidine synthase A like protein DUF5641 PF18701.1 KFM73305.1 - 3.1e-11 43.3 0.1 3.4e-11 43.2 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5641) CLU PF13236.6 KFM73307.1 - 6.1e-89 297.6 0.0 1.6e-88 296.2 0.0 1.8 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 KFM73307.1 - 4.3e-54 183.2 1.1 8.1e-54 182.3 0.1 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KFM73307.1 - 1.8e-21 76.2 7.1 2.3e-11 43.8 0.1 3.5 1 1 1 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.6 KFM73307.1 - 9.5e-15 54.7 0.1 3e-14 53.1 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KFM73307.1 - 5.3e-13 48.4 5.6 5.2e-05 23.0 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM73307.1 - 1.6e-06 27.8 1.5 3e-06 26.9 1.2 1.5 1 1 0 1 1 1 1 MalT-like TPR region DUF727 PF05303.12 KFM73307.1 - 2e-05 24.6 0.0 7.6e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 KFM73307.1 - 0.0003 20.7 3.1 0.63 10.3 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM73307.1 - 0.00079 19.5 0.2 0.63 10.4 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM73307.1 - 0.033 14.0 0.1 0.033 14.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad60-SLD PF11976.8 KFM73307.1 - 0.066 13.1 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DARPP-32 PF05395.12 KFM73307.1 - 0.14 12.3 3.6 0.61 10.3 3.6 2.0 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 RPA_interact_C PF14768.6 KFM73308.1 - 1.1e-17 64.4 8.0 2e-17 63.5 8.0 1.5 1 0 0 1 1 1 1 Replication protein A interacting C-terminal RPA_interact_N PF14766.6 KFM73308.1 - 4e-15 55.1 5.8 7.7e-15 54.3 5.8 1.5 1 0 0 1 1 1 1 Replication protein A interacting N-terminal NS3 PF17530.2 KFM73308.1 - 0.0048 16.5 0.2 0.011 15.3 0.1 1.7 1 1 0 1 1 1 1 Non-structural protein NS3 RPA_interact_M PF14767.6 KFM73308.1 - 0.019 15.5 10.4 0.019 15.5 10.4 1.8 2 0 0 2 2 2 0 Replication protein A interacting middle DNA_pol_alpha_N PF12254.8 KFM73308.1 - 0.22 11.6 1.1 2.9 8.1 0.1 2.4 1 1 1 2 2 2 0 DNA polymerase alpha subunit p180 N terminal MFS_1 PF07690.16 KFM73310.1 - 1.6e-34 119.4 60.8 5.3e-30 104.5 40.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFM73310.1 - 1.3e-10 40.7 28.6 1.5e-09 37.2 26.4 2.9 1 1 0 1 1 1 1 MFS_1 like family HEAT PF02985.22 KFM73311.1 - 0.032 14.5 0.1 1.7e+02 2.9 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat zf-H2C2_2 PF13465.6 KFM73312.1 - 4.9e-43 143.7 71.1 1e-10 41.5 1.4 11.5 11 1 0 11 11 11 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73312.1 - 2.1e-34 116.1 78.2 7.1e-06 26.2 0.6 10.6 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73312.1 - 3.5e-32 108.3 75.6 2.4e-05 24.8 0.9 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM73312.1 - 1.6e-14 53.7 51.4 0.035 14.4 1.1 10.4 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM73312.1 - 7.3e-08 32.5 58.6 0.00084 19.6 1.5 9.9 10 0 0 10 10 10 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM73312.1 - 1e-07 31.7 67.1 0.0009 19.2 0.5 10.2 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2HE PF16278.5 KFM73312.1 - 0.00048 20.5 65.3 0.0027 18.1 1.2 10.1 2 2 7 9 9 9 4 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KFM73312.1 - 0.001 18.7 64.6 0.69 9.7 1.0 10.5 11 0 0 11 11 11 6 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFM73312.1 - 0.0019 18.5 51.6 0.99 9.8 0.3 9.9 2 2 8 10 10 10 4 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFM73312.1 - 0.0031 17.6 42.0 0.021 14.9 0.8 7.4 3 2 6 9 9 9 4 Zinc ribbon domain zf-trcl PF13451.6 KFM73312.1 - 0.02 14.7 1.0 0.02 14.7 1.0 8.3 9 1 0 9 9 9 0 Probable zinc-ribbon domain CpXC PF14353.6 KFM73312.1 - 0.12 12.5 0.4 0.12 12.5 0.4 7.1 2 2 4 7 7 7 0 CpXC protein zinc_ribbon_15 PF17032.5 KFM73312.1 - 0.29 11.9 39.4 0.29 11.9 0.4 6.4 2 2 3 6 6 6 0 zinc-ribbon family zf-MYST PF17772.1 KFM73312.1 - 0.95 9.1 0.0 0.95 9.1 0.0 6.9 5 2 2 7 7 7 0 MYST family zinc finger domain zf_C2H2_13 PF18508.1 KFM73312.1 - 0.99 9.0 13.7 28 4.4 0.0 6.4 6 0 0 6 6 6 0 Zinc finger domain HypA PF01155.19 KFM73312.1 - 1.4 8.9 33.0 3.9 7.5 2.6 5.8 2 2 3 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PyrI_C PF02748.15 KFM73312.1 - 4.5 7.2 38.4 1.2 9.1 2.3 8.8 7 3 3 10 10 10 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_UBZ PF18439.1 KFM73312.1 - 8.5 6.1 34.1 12 5.5 0.1 9.0 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger Rad21_Rec8 PF04824.16 KFM73314.1 - 8.7e-09 34.5 0.8 1.2e-08 34.1 0.8 1.2 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein GRAS PF03514.14 KFM73314.1 - 0.0095 14.9 0.1 0.011 14.7 0.1 1.0 1 0 0 1 1 1 1 GRAS domain family DUF4852 PF16144.5 KFM73314.1 - 0.019 15.1 0.4 0.022 14.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) O-FucT PF10250.9 KFM73314.1 - 0.043 13.5 0.3 0.044 13.5 0.3 1.0 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Tox-PLDMTX PF15645.6 KFM73315.1 - 0.031 14.6 1.0 0.048 13.9 0.5 1.6 1 1 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold Pkinase PF00069.25 KFM73316.1 - 5.8e-48 163.5 0.0 7e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73316.1 - 4.5e-18 65.5 0.0 5.8e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM73316.1 - 0.0018 17.3 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain CDC4_D PF16856.5 KFM73316.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain DDE_3 PF13358.6 KFM73317.1 - 3.5e-06 26.8 0.0 3.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73318.1 - 1.5e-07 31.1 0.1 1.8e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM73318.1 - 0.0042 16.9 0.0 0.0052 16.6 0.0 1.1 1 0 0 1 1 1 1 Tc3 transposase HTH_23 PF13384.6 KFM73318.1 - 0.0098 15.7 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_50 PF18024.1 KFM73318.1 - 0.066 12.8 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3762 PF12591.8 KFM73318.1 - 0.12 12.7 1.2 0.75 10.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3762) HTH_24 PF13412.6 KFM73318.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding BSD PF03909.17 KFM73320.1 - 3.6e-14 52.5 0.7 7.2e-14 51.5 0.7 1.5 1 0 0 1 1 1 1 BSD domain DUF1451 PF07295.11 KFM73320.1 - 0.21 11.6 1.6 0.59 10.2 1.4 1.8 1 1 0 1 1 1 0 Zinc-ribbon containing domain Tetraspanin PF00335.20 KFM73321.1 - 2.8e-24 86.1 10.9 3.3e-24 85.9 10.9 1.1 1 0 0 1 1 1 1 Tetraspanin family LST1 PF05083.13 KFM73321.1 - 0.042 14.1 0.3 0.086 13.1 0.3 1.6 1 0 0 1 1 1 0 LST-1 protein CD20 PF04103.15 KFM73321.1 - 0.083 13.0 12.2 0.21 11.7 12.0 1.9 1 1 0 1 1 1 0 CD20-like family DUF2981 PF11200.8 KFM73321.1 - 0.11 12.2 0.4 0.14 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF3487 PF11990.8 KFM73321.1 - 1.3 8.9 8.7 9.3 6.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) Fun_ATP-synt_8 PF05933.13 KFM73321.1 - 5.1 7.3 10.4 0.27 11.4 0.3 2.9 3 0 0 3 3 3 0 Fungal ATP synthase protein 8 (A6L) DDE_3 PF13358.6 KFM73323.1 - 3.7e-16 59.2 0.1 3e-15 56.3 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73323.1 - 1.4e-10 41.2 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM73324.1 - 4e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73324.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73324.1 - 1.9e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73324.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73324.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 KFM73325.1 - 9.1e-93 300.9 107.9 1.8e-08 34.5 1.4 13.1 13 0 0 13 13 13 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73325.1 - 7.8e-55 180.4 129.8 1.1e-05 25.6 3.2 13.1 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73325.1 - 1.6e-40 134.2 113.7 0.00083 20.0 1.7 13.1 13 0 0 13 13 13 12 C2H2-type zinc finger zf-met PF12874.7 KFM73325.1 - 1e-25 89.3 111.9 0.00085 19.6 2.4 13.2 13 0 0 13 13 13 12 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM73325.1 - 3.6e-24 84.2 72.0 0.028 14.2 0.2 12.4 12 0 0 12 12 12 11 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM73325.1 - 9.8e-22 76.7 82.6 0.029 14.7 0.8 13.1 13 0 0 13 13 13 11 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM73325.1 - 2.1e-20 72.1 81.2 0.013 15.2 0.5 13.2 13 0 0 13 13 12 11 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM73325.1 - 1.6e-14 53.5 101.2 0.031 14.3 1.0 13.5 13 0 0 13 13 13 9 C2H2-type zinc finger zf-RRPl_C4 PF17026.5 KFM73325.1 - 6.7e-07 29.4 62.3 0.024 14.7 9.2 6.2 1 1 5 6 6 6 5 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFM73325.1 - 1.4e-05 25.7 59.6 0.21 12.4 1.7 6.7 4 2 1 6 6 6 5 zinc-ribbon family DUF2039 PF10217.9 KFM73325.1 - 1.5e-05 25.2 54.1 0.34 11.3 2.9 6.8 1 1 5 6 6 6 4 Uncharacterized conserved protein (DUF2039) zf-Sec23_Sec24 PF04810.15 KFM73325.1 - 8.2e-05 22.6 51.2 3.8 7.6 0.2 11.7 5 5 7 12 12 12 2 Sec23/Sec24 zinc finger Tox-HNH-HHH PF15637.6 KFM73325.1 - 0.00046 20.3 15.0 2 8.6 0.8 5.1 1 1 4 5 5 5 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2HC_2 PF13913.6 KFM73325.1 - 0.0038 17.1 49.9 3.8 7.5 0.1 12.8 13 0 0 13 13 13 1 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM73325.1 - 0.0063 16.6 48.7 29 4.9 0.1 12.7 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM73325.1 - 0.014 15.4 50.9 1.7 8.7 1.7 8.8 3 2 6 9 9 9 0 Adenylate kinase, active site lid zf-C2H2_9 PF16293.5 KFM73325.1 - 0.033 14.0 56.3 1.5 8.7 0.3 11.8 1 1 11 12 12 12 0 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM73325.1 - 0.073 13.2 65.9 7.5 6.8 0.2 12.5 13 0 0 13 13 12 0 DBF zinc finger NAD_kinase PF01513.21 KFM73325.1 - 0.31 10.2 3.1 47 3.0 2.8 4.0 1 1 1 2 2 2 0 ATP-NAD kinase Amidohydro_1 PF01979.20 KFM73325.1 - 1.4 8.1 26.3 6.2 6.0 0.6 6.3 1 1 6 7 7 7 0 Amidohydrolase family C1_1 PF00130.22 KFM73325.1 - 2.4 8.1 85.2 6.2 6.8 0.7 12.2 4 3 6 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SKA2 PF16740.5 KFM73325.1 - 3.2 7.6 6.8 11 5.9 0.0 4.4 2 2 4 6 6 6 0 Spindle and kinetochore-associated protein 2 GAGA PF09237.11 KFM73325.1 - 3.3 7.6 31.1 9.2 6.2 0.2 8.3 1 1 9 11 11 11 0 GAGA factor zf-Paramyx-P PF13008.7 KFM73325.1 - 4.3 6.9 46.1 18 4.9 0.1 11.4 13 0 0 13 13 13 0 Zinc-binding domain of Paramyxoviridae V protein YyzF PF14116.6 KFM73325.1 - 7.1 6.7 55.8 25 5.0 0.2 12.5 13 0 0 13 13 13 0 YyzF-like protein zf-C2H2 PF00096.26 KFM73328.1 - 8.7 7.0 35.1 0.84 10.2 0.2 6.5 6 0 0 6 6 6 0 Zinc finger, C2H2 type Hairy_orange PF07527.13 KFM73331.1 - 1.1e-12 47.9 0.2 2.2e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 Hairy Orange zf-MIZ PF02891.20 KFM73331.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger MRP-S35 PF10246.9 KFM73332.1 - 4.7e-23 81.1 0.0 6.9e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 RRM_1 PF00076.22 KFM73334.1 - 2e-18 65.9 0.0 2.7e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFM73334.1 - 3.1e-06 27.0 5.5 7.5e-06 25.8 5.5 1.7 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 KFM73334.1 - 0.00024 20.7 0.0 0.00033 20.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_5 PF14787.6 KFM73334.1 - 0.0017 18.0 2.6 0.0048 16.6 2.6 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KFM73334.1 - 0.043 13.8 2.7 0.08 12.9 2.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_S27e PF01667.17 KFM73335.1 - 5.5e-29 99.6 6.0 7.2e-29 99.3 6.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 DDE_3 PF13358.6 KFM73336.1 - 2.3e-20 72.8 0.0 1.7e-13 50.5 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73336.1 - 2.3e-16 59.8 2.2 4.8e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase Neur_chan_memb PF02932.16 KFM73337.1 - 2.8e-35 122.5 1.6 3.2e-35 122.3 1.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RDD PF06271.12 KFM73337.1 - 0.2 11.8 4.2 0.3 11.3 4.2 1.2 1 0 0 1 1 1 0 RDD family Ig_3 PF13927.6 KFM73339.1 - 2.4e-23 82.5 4.9 5.5e-12 46.1 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM73339.1 - 7.7e-17 61.2 0.6 2.1e-11 43.7 0.1 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM73339.1 - 8.5e-16 58.1 2.6 3.5e-08 33.7 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM73339.1 - 7.5e-15 54.9 4.2 4.6e-05 23.5 0.3 3.3 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFM73339.1 - 9.9e-10 38.4 0.3 6.4e-07 29.4 0.0 3.3 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM73339.1 - 3.5e-05 23.9 0.7 0.12 12.6 0.1 3.4 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM73339.1 - 0.0014 18.8 1.2 0.43 10.9 0.1 3.2 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM73339.1 - 0.024 15.0 0.8 0.34 11.3 0.1 2.9 3 0 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 KFM73339.1 - 0.095 12.5 0.9 0.45 10.3 0.9 2.2 1 1 0 1 1 1 0 Adenovirus E3 region protein CR1 RCC1_2 PF13540.6 KFM73339.1 - 0.12 12.2 0.4 0.26 11.2 0.4 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat FeoB_associated PF12669.7 KFM73339.1 - 1.7 9.1 3.6 3.3 8.2 3.6 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein zf-C2H2 PF00096.26 KFM73340.1 - 1.8e-16 59.6 16.0 6.7e-06 26.3 1.4 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73340.1 - 3.6e-12 46.0 14.4 0.00021 21.8 1.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM73340.1 - 0.00011 22.3 8.8 0.16 12.3 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM73340.1 - 0.00013 21.9 12.8 0.11 12.6 0.4 3.2 2 1 1 3 3 3 2 C2H2-type zinc finger C1_4 PF07975.12 KFM73340.1 - 0.0004 20.5 2.6 0.0012 19.1 1.4 1.9 2 0 0 2 2 2 1 TFIIH C1-like domain zf-H2C2_2 PF13465.6 KFM73340.1 - 0.00049 20.4 15.7 0.0022 18.3 0.6 3.8 4 0 0 4 4 4 2 Zinc-finger double domain LIM PF00412.22 KFM73340.1 - 0.00058 20.0 5.0 0.0012 19.1 3.0 2.1 1 1 1 2 2 2 2 LIM domain zf-met PF12874.7 KFM73340.1 - 0.00087 19.6 11.1 0.12 12.9 0.6 3.5 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KFM73340.1 - 0.0085 16.0 6.9 1.7 8.6 0.3 3.1 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger EGF_CA PF07645.15 KFM73340.1 - 0.017 15.3 3.0 0.97 9.7 0.3 2.4 2 1 0 3 3 3 0 Calcium-binding EGF domain zf_C2H2_ZHX PF18387.1 KFM73340.1 - 0.02 14.5 5.7 0.47 10.1 0.2 2.5 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Prok-RING_1 PF14446.6 KFM73340.1 - 0.027 14.4 1.0 5.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Actin_micro PF17003.5 KFM73340.1 - 0.027 13.6 5.8 0.32 10.2 0.7 2.0 1 1 1 2 2 2 0 Putative actin-like family zf-C2H2_3 PF13878.6 KFM73340.1 - 0.033 14.0 4.6 1.7 8.5 0.1 3.2 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_11 PF16622.5 KFM73340.1 - 0.037 13.8 0.2 0.037 13.8 0.2 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFM73340.1 - 0.043 14.5 3.9 1.9 9.2 0.3 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KFM73340.1 - 0.046 13.3 3.8 0.66 9.6 0.2 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger SPARC_Ca_bdg PF10591.9 KFM73340.1 - 0.07 13.5 1.6 1.3 9.4 0.2 2.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region zf-Di19 PF05605.12 KFM73340.1 - 0.07 13.4 6.7 0.12 12.6 0.6 2.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 KFM73340.1 - 0.14 12.3 3.4 0.48 10.6 0.2 2.6 1 1 2 3 3 3 0 Zic proteins zinc finger domain DUF629 PF04780.12 KFM73340.1 - 0.16 10.4 5.9 0.27 9.7 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Zn_Tnp_IS1595 PF12760.7 KFM73340.1 - 0.23 11.5 4.6 6 6.9 0.6 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 KFM73340.1 - 0.26 11.8 8.0 0.98 9.9 1.3 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_4 PF13717.6 KFM73340.1 - 0.3 11.0 3.8 4.6 7.3 3.8 2.3 1 1 1 2 2 2 0 zinc-ribbon domain zf-C2H2_8 PF15909.5 KFM73340.1 - 0.32 11.3 6.2 2.7 8.3 6.2 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon RIG-I_C-RD PF11648.8 KFM73340.1 - 0.87 9.8 4.9 11 6.3 0.1 2.6 1 1 2 3 3 3 0 C-terminal domain of RIG-I FYVE PF01363.21 KFM73340.1 - 1.1 9.4 9.9 2.6 8.3 7.5 2.1 1 1 1 2 2 2 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 KFM73340.1 - 3.8 7.7 6.6 12 6.1 4.4 2.4 2 1 1 3 3 3 0 Zinc ribbon domain zf-H2C2_5 PF13909.6 KFM73340.1 - 6.2 6.7 16.2 9 6.2 0.1 3.9 3 1 0 3 3 3 0 C2H2-type zinc-finger domain DDE_3 PF13358.6 KFM73341.1 - 3e-16 59.5 0.1 3.2e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73341.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Asp23 PF03780.13 KFM73342.1 - 1.6e-12 47.8 8.3 1.6 9.2 0.2 7.5 1 1 7 8 8 8 8 Asp23 family, cell envelope-related function PUA PF01472.20 KFM73342.1 - 9.3e-12 44.7 26.9 6.1 6.9 0.2 9.7 1 1 17 18 18 18 17 PUA domain RE_CfrBI PF09516.10 KFM73342.1 - 4.7e-09 36.0 4.0 5 6.5 3.9 7.2 1 1 1 2 2 2 2 CfrBI restriction endonuclease DUF2857 PF11198.8 KFM73342.1 - 1.9e-08 34.3 9.6 6.8 6.4 0.1 7.1 1 1 9 10 10 10 9 Protein of unknown function (DUF2857) RPA_C PF08784.11 KFM73342.1 - 1.9e-07 31.7 8.5 9.8 6.9 0.3 6.6 1 1 7 8 8 8 2 Replication protein A C terminal HTH_9 PF08221.11 KFM73342.1 - 3.5e-05 23.8 15.1 1.4e+02 2.7 0.1 8.3 1 1 17 18 18 18 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM73343.1 - 4.2e-16 58.9 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73343.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73343.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73343.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73343.1 - 9.2 7.0 18.1 0.11 13.1 1.9 3.4 3 1 1 4 4 4 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM73344.1 - 1.4e-69 235.1 1.5 1.7e-69 234.8 1.5 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM73344.1 - 2.8e-05 24.8 7.9 2.8e-05 24.8 7.9 1.9 2 0 0 2 2 2 1 DDE_Tnp_1-like zinc-ribbon zf-B_box PF00643.24 KFM73344.1 - 0.063 13.4 3.8 0.13 12.5 3.8 1.5 1 0 0 1 1 1 0 B-box zinc finger IBR PF01485.21 KFM73344.1 - 0.078 13.2 7.3 0.22 11.8 7.3 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain C1_2 PF03107.16 KFM73344.1 - 1.1 9.7 7.5 2.9 8.3 7.5 1.8 1 1 0 1 1 1 0 C1 domain PHD PF00628.29 KFM73344.1 - 2.7 8.0 8.6 0.69 9.8 4.6 2.1 2 0 0 2 2 2 0 PHD-finger DUF4817 PF16087.5 KFM73345.1 - 7.8e-06 25.6 0.0 2.6e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain (DUF4817) PI3_PI4_kinase PF00454.27 KFM73350.1 - 4.8e-51 174.0 0.1 4.4e-36 125.0 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 KFM73350.1 - 0.0026 17.1 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) zf-C2H2_11 PF16622.5 KFM73350.1 - 0.073 12.8 0.6 0.13 12.0 0.6 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type Na_sulph_symp PF00939.19 KFM73351.1 - 1.7e-19 70.3 10.9 1.9e-19 70.1 10.9 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFM73351.1 - 2.5e-06 26.9 10.5 2.6e-06 26.8 10.5 1.0 1 0 0 1 1 1 1 Citrate transporter DUF1071 PF06378.11 KFM73351.1 - 0.027 14.1 0.0 0.043 13.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1071) DUF5584 PF17822.1 KFM73351.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5584) TRAPP PF04051.16 KFM73352.1 - 2.5e-39 134.3 0.1 2.8e-39 134.1 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ricin_B_lectin PF00652.22 KFM73354.1 - 4.4e-14 52.8 0.2 5.9e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KFM73354.1 - 0.17 12.6 0.0 4.2 8.2 0.0 2.2 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like DDE_3 PF13358.6 KFM73355.1 - 2.5e-10 40.3 0.0 3.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease US30 PF17624.2 KFM73357.1 - 0.11 11.5 0.3 0.13 11.2 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function THEG PF14912.6 KFM73357.1 - 0.11 12.9 0.1 0.25 11.8 0.1 1.8 1 1 0 1 1 1 0 Testicular haploid expressed repeat DUF4371 PF14291.6 KFM73358.1 - 1.1e-09 38.3 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) HTH_Tnp_Tc3_2 PF01498.18 KFM73359.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73359.1 - 8.9e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73360.1 - 8.9e-21 73.9 0.7 2.3e-19 69.4 1.8 2.4 3 0 0 3 3 2 1 Transposase DDE_3 PF13358.6 KFM73360.1 - 5.7e-17 61.8 0.7 1.4e-09 37.9 0.0 4.0 3 1 1 4 4 4 3 DDE superfamily endonuclease HTH_7 PF02796.15 KFM73360.1 - 2.1e-07 30.9 0.4 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM73360.1 - 3.5e-07 30.7 2.0 3.5e-07 30.7 2.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73360.1 - 9.9e-07 28.8 2.5 7.5e-05 22.8 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73360.1 - 1.7e-06 27.6 3.4 2.5e-05 23.9 0.0 3.0 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM73360.1 - 2.8e-06 27.2 0.7 3.9e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM73360.1 - 0.00018 21.3 1.4 0.0017 18.2 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KFM73360.1 - 0.0011 18.9 0.3 0.016 15.2 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM73360.1 - 0.02 14.6 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM73360.1 - 0.043 13.9 0.1 1.9 8.6 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM73360.1 - 0.09 13.0 0.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM73360.1 - 0.13 11.8 0.2 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM73360.1 - 0.17 12.0 0.0 29 4.8 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM73360.1 - 0.22 11.3 3.9 1.4 8.7 0.0 3.2 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM73360.1 - 1.1 8.8 3.6 7 6.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.6 KFM73361.1 - 1.5e-10 41.0 0.0 1.7e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73362.1 - 2.6e-16 59.6 2.2 5e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73362.1 - 4.4e-14 52.5 0.0 7.2e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM73364.1 - 1.6e-15 57.2 0.0 2.4e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73364.1 - 2.3e-10 40.6 2.9 2.7e-10 40.3 1.0 2.0 2 0 0 2 2 2 1 Transposase RNase_H PF00075.24 KFM73364.1 - 5.3e-07 29.9 0.0 8.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 RNase H Prefoldin_2 PF01920.20 KFM73365.1 - 3.5e-19 68.7 7.4 4.2e-19 68.5 7.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.9 KFM73365.1 - 0.0036 17.3 7.9 0.0069 16.4 2.3 2.1 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PI3K_P85_iSH2 PF16454.5 KFM73365.1 - 0.0042 16.7 7.6 0.0056 16.3 7.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Herpes_UL6 PF01763.16 KFM73365.1 - 0.039 12.5 2.3 0.047 12.2 2.3 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like Met_asp_mut_E PF06368.11 KFM73365.1 - 0.053 12.0 0.0 0.054 12.0 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) STAT_alpha PF01017.20 KFM73365.1 - 0.1 12.5 5.7 0.13 12.2 5.7 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain MutS_II PF05188.17 KFM73365.1 - 0.17 12.2 2.2 0.25 11.6 0.2 1.9 2 0 0 2 2 2 0 MutS domain II TMPIT PF07851.13 KFM73365.1 - 0.35 10.1 4.3 0.43 9.8 4.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Uds1 PF15456.6 KFM73365.1 - 0.52 10.5 8.0 0.78 9.9 1.4 2.2 1 1 1 2 2 2 0 Up-regulated During Septation Snapin_Pallidin PF14712.6 KFM73365.1 - 0.64 10.5 9.0 0.2 12.1 1.2 2.3 2 1 0 2 2 2 0 Snapin/Pallidin Integrase_H2C2 PF17921.1 KFM73366.1 - 2.3e-07 30.8 0.5 3.8e-07 30.1 0.5 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM73366.1 - 0.0045 17.2 0.2 0.01 16.1 0.2 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Fanconi_A_N PF15865.5 KFM73366.1 - 0.061 12.7 0.1 0.087 12.2 0.1 1.2 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus SPECT1 PF18680.1 KFM73367.1 - 0.031 13.9 0.1 0.032 13.9 0.1 1.1 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 DUF1759 PF03564.15 KFM73368.1 - 5.4e-08 32.9 0.0 6.1e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DNA_pol3_delt_C PF14840.6 KFM73368.1 - 0.02 15.2 0.5 0.023 15.0 0.5 1.1 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Nup188 PF10487.9 KFM73368.1 - 0.043 11.7 0.0 0.044 11.7 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 HTH_Tnp_Tc3_2 PF01498.18 KFM73369.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73369.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73369.1 - 1.9e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73369.1 - 0.0025 17.5 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73369.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain AAA_18 PF13238.6 KFM73370.1 - 9.9e-12 45.5 0.0 1.4e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFM73370.1 - 0.0016 18.8 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM73370.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KFM73370.1 - 0.0079 16.0 0.0 0.41 10.3 0.0 2.3 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 KFM73370.1 - 0.019 15.1 0.0 0.04 14.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase IFS PF16718.5 KFM73370.1 - 0.026 14.6 0.0 0.062 13.4 0.0 1.6 1 1 0 1 1 1 0 Immunity factor for SPN CoaE PF01121.20 KFM73370.1 - 0.031 13.9 0.0 0.049 13.3 0.0 1.4 1 1 0 1 1 1 0 Dephospho-CoA kinase Zeta_toxin PF06414.12 KFM73370.1 - 0.054 12.8 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 KFM73370.1 - 0.063 13.5 0.0 0.092 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM73370.1 - 0.12 12.7 0.1 0.92 9.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain NRDE-2 PF08424.10 KFM73371.1 - 5.1e-07 29.1 11.9 0.0012 18.0 0.3 4.4 1 1 3 4 4 4 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KFM73371.1 - 2.4e-05 24.8 4.6 0.64 11.0 0.1 4.8 4 2 2 6 6 6 2 Tetratricopeptide repeat FlgM PF04316.13 KFM73371.1 - 0.035 14.5 0.3 0.1 13.0 0.3 1.8 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM B12-binding_2 PF02607.17 KFM73371.1 - 0.035 14.5 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 B12 binding domain FB_lectin PF07367.11 KFM73371.1 - 0.041 13.8 0.9 0.11 12.4 0.9 1.8 1 1 0 1 1 1 0 Fungal fruit body lectin HD_4 PF13328.6 KFM73371.1 - 0.11 12.2 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 HD domain FtsX_ECD PF18075.1 KFM73371.1 - 2 9.1 5.3 14 6.4 0.0 3.3 2 1 1 3 3 3 0 FtsX extracellular domain YL1 PF05764.13 KFM73371.1 - 2.8 8.0 7.5 26 4.8 0.0 2.3 2 0 0 2 2 2 0 YL1 nuclear protein RRM_1 PF00076.22 KFM73372.1 - 6.8e-19 67.5 0.0 1.3e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM73372.1 - 0.0051 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFM73372.1 - 0.0055 16.7 2.3 0.013 15.5 0.0 2.6 3 0 0 3 3 3 1 RNA binding motif COG2 PF06148.11 KFM73372.1 - 0.0073 16.4 0.2 0.025 14.6 0.1 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Nup35_RRM PF05172.13 KFM73372.1 - 0.016 15.2 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif KCNQ2_u3 PF16642.5 KFM73372.1 - 0.098 13.7 7.2 0.13 13.2 2.0 2.7 2 1 1 3 3 3 0 Unstructured region on Potassium channel subunit alpha KvLQT2 CENP-Q PF13094.6 KFM73372.1 - 0.3 11.3 7.2 0.4 10.9 6.0 2.0 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YabA PF06156.13 KFM73372.1 - 5 7.8 8.9 0.65 10.7 2.0 2.8 3 1 1 4 4 4 0 Initiation control protein YabA CENP-H PF05837.12 KFM73372.1 - 5.7 7.4 8.6 0.51 10.8 3.0 2.0 2 1 0 2 2 2 0 Centromere protein H (CENP-H) LSM_int_assoc PF16605.5 KFM73373.1 - 3.1e-08 33.6 4.1 6.4e-08 32.6 4.1 1.7 1 1 0 1 1 1 1 LSM-interacting associated unstructured Ig_3 PF13927.6 KFM73375.1 - 6.2e-76 251.0 9.4 8e-12 45.6 0.0 7.5 7 0 0 7 7 7 7 Immunoglobulin domain Ig_2 PF13895.6 KFM73375.1 - 1.9e-62 207.6 5.2 7.2e-09 35.9 0.0 8.0 7 1 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 KFM73375.1 - 5.2e-57 189.9 0.3 4.6e-14 52.3 0.0 8.9 7 3 0 7 7 7 7 Immunoglobulin I-set domain ig PF00047.25 KFM73375.1 - 3.9e-48 161.6 1.5 4e-08 33.3 0.0 8.7 7 2 0 7 7 7 7 Immunoglobulin domain C2-set_2 PF08205.12 KFM73375.1 - 1.7e-23 82.5 1.4 1.5e-08 34.6 0.0 6.1 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM73375.1 - 1.2e-20 73.7 13.4 0.0024 18.0 0.0 10.4 6 5 4 10 10 10 4 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM73375.1 - 2.1e-14 53.5 0.2 0.012 15.9 0.0 7.1 7 0 0 7 7 7 3 T-cell surface glycoprotein CD3 delta chain fn3 PF00041.21 KFM73375.1 - 2.1e-11 44.0 0.1 2e-10 40.9 0.1 2.7 3 0 0 3 3 3 1 Fibronectin type III domain C1-set PF07654.15 KFM73375.1 - 1e-09 38.7 0.0 0.24 11.8 0.0 5.6 6 0 0 6 6 6 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFM73375.1 - 4.8e-06 26.1 0.1 2.5 7.7 0.0 5.3 6 0 0 6 6 6 1 Immunoglobulin domain V-set_CD47 PF08204.11 KFM73375.1 - 0.03 14.3 0.0 2.5 8.1 0.0 3.4 2 1 1 3 3 3 0 CD47 immunoglobulin-like domain TMIE PF16038.5 KFM73375.1 - 0.036 13.9 0.6 0.069 13.0 0.6 1.3 1 0 0 1 1 1 0 TMIE protein LST1 PF05083.13 KFM73375.1 - 0.044 14.1 0.5 0.044 14.1 0.5 2.6 3 0 0 3 3 3 0 LST-1 protein EphA2_TM PF14575.6 KFM73375.1 - 0.047 14.6 0.0 0.1 13.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pur_ac_phosph_N PF16656.5 KFM73375.1 - 0.076 13.6 0.2 1.8 9.2 0.2 3.3 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Orthoreo_P10 PF07204.11 KFM73375.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Shisa PF13908.6 KFM73375.1 - 0.086 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Cadherin_C_2 PF16492.5 KFM73375.1 - 0.14 12.9 0.0 0.47 11.2 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal FAM176 PF14851.6 KFM73375.1 - 0.17 11.5 0.1 0.34 10.5 0.1 1.4 1 0 0 1 1 1 0 FAM176 family Sec16_C PF12931.7 KFM73376.1 - 4.1e-08 33.2 1.1 5.2e-06 26.3 1.1 2.5 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 KFM73376.1 - 2.9e-05 24.7 12.2 0.077 13.9 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Prp18 PF02840.15 KFM73376.1 - 0.00056 20.0 0.2 0.0011 19.0 0.2 1.4 1 0 0 1 1 1 1 Prp18 domain SRA1 PF07304.11 KFM73376.1 - 0.0062 16.3 0.0 0.0062 16.3 0.0 2.9 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) DUF3958 PF13125.6 KFM73376.1 - 0.035 14.3 1.4 0.075 13.2 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Peptidase_C65 PF10275.9 KFM73376.1 - 0.11 11.9 0.1 9.2 5.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain DUF4404 PF14357.6 KFM73376.1 - 1.6 9.4 3.5 2.1 9.0 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) HTH_Tnp_Tc3_2 PF01498.18 KFM73377.1 - 2.1e-16 59.9 2.2 3.9e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73377.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease COesterase PF00135.28 KFM73379.1 - 7.7e-31 107.5 0.4 9e-31 107.3 0.4 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KFM73380.1 - 1.7e-99 334.1 0.0 1.9e-99 333.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM73380.1 - 1.2e-08 35.0 0.0 2.8e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM73380.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.3 1 1 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 KFM73381.1 - 5.7e-37 127.7 0.1 6.2e-37 127.6 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KFM73382.1 - 2.6e-88 297.1 0.0 3.2e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM73382.1 - 4.7e-08 33.2 0.1 1.5e-07 31.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM73382.1 - 0.079 12.4 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Y_phosphatase PF00102.27 KFM73383.1 - 3.7e-46 157.6 0.0 9.8e-46 156.2 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM73383.1 - 0.004 17.0 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM73383.1 - 0.085 12.8 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family DDE_3 PF13358.6 KFM73384.1 - 2.1e-12 47.0 0.1 3.3e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease KH_1 PF00013.29 KFM73385.1 - 7.7e-16 57.7 2.5 1.4e-15 56.8 2.5 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 KFM73385.1 - 0.0045 16.8 0.5 0.015 15.1 0.5 1.9 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KFM73385.1 - 0.015 15.1 0.1 0.043 13.7 0.1 1.8 1 0 0 1 1 1 0 KH domain Imm40 PF15569.6 KFM73386.1 - 0.034 14.3 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 40 Prok-E2_E PF14462.6 KFM73386.1 - 0.049 13.4 0.0 0.06 13.2 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family E EMP70 PF02990.16 KFM73388.1 - 6.6e-167 556.3 20.8 8.8e-167 555.9 20.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 EVC2_like PF12297.8 KFM73388.1 - 0.51 9.0 1.2 17 3.9 0.0 2.2 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Exo_endo_phos PF03372.23 KFM73389.1 - 3.3e-21 75.9 0.0 1.5e-20 73.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cbl_N3 PF02762.14 KFM73389.1 - 0.13 12.1 0.1 0.41 10.5 0.1 1.8 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73390.1 - 1.2e-19 70.3 3.1 4.2e-19 68.6 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73390.1 - 2.7e-16 59.6 0.0 1.5e-15 57.2 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM73390.1 - 5.1e-06 27.0 4.3 5.4e-06 26.9 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM73390.1 - 0.05 13.5 0.4 1.2 9.1 0.0 2.6 2 1 1 3 3 3 0 MarR family Spaetzle PF16077.5 KFM73391.1 - 2.8e-21 75.9 10.1 5.3e-21 75.0 9.5 1.7 2 0 0 2 2 2 1 Spaetzle Coagulin PF02035.15 KFM73391.1 - 3.2e-07 30.4 1.7 3.8e-07 30.2 1.7 1.1 1 0 0 1 1 1 1 Coagulin Ribosomal_S24e PF01282.19 KFM73392.1 - 5.9e-40 135.1 0.0 7.5e-40 134.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S24e Brix PF04427.18 KFM73394.1 - 1.2e-31 110.3 0.1 1.7e-31 109.8 0.1 1.2 1 0 0 1 1 1 1 Brix domain HTH_Tnp_Tc3_2 PF01498.18 KFM73395.1 - 3.8e-16 59.1 3.5 5.5e-16 58.6 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73395.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73395.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73395.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73395.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain SCAN PF02023.17 KFM73396.1 - 0.00018 21.3 0.5 0.00065 19.5 0.3 2.1 2 0 0 2 2 2 1 SCAN domain RVP PF00077.20 KFM73396.1 - 0.00036 20.8 0.0 0.00081 19.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 KFM73396.1 - 0.00072 19.5 0.6 0.0016 18.5 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 KFM73396.1 - 0.089 13.4 0.1 0.33 11.5 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Xpo1 PF08389.12 KFM73396.1 - 0.14 12.2 1.3 0.34 11.0 0.1 2.4 3 0 0 3 3 3 0 Exportin 1-like protein dUTPase PF00692.19 KFM73397.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 dUTPase HTH_Tnp_Tc3_2 PF01498.18 KFM73398.1 - 5.2e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73398.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73398.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73398.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73398.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_48 PF17906.1 KFM73399.1 - 4.9e-05 23.4 0.0 8.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Arc_C PF18162.1 KFM73400.1 - 0.00033 20.4 0.4 0.0011 18.8 0.4 1.8 1 0 0 1 1 1 1 Arc C-lobe Retrotrans_gag PF03732.17 KFM73400.1 - 0.026 14.8 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein HTH_Tnp_Tc3_2 PF01498.18 KFM73401.1 - 1.2e-16 60.7 2.7 1.2e-16 60.7 2.7 1.9 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 KFM73401.1 - 0.00033 20.7 1.6 0.0014 18.7 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM73401.1 - 0.067 12.6 1.3 0.16 11.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.6 KFM73403.1 - 2.8e-16 59.6 0.1 3.2e-15 56.1 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73403.1 - 1.4e-10 41.3 1.0 2.8e-10 40.3 1.0 1.6 1 0 0 1 1 1 1 Transposase DDE_1 PF03184.19 KFM73405.1 - 4.7e-15 55.7 0.3 6.3e-11 42.2 0.0 2.6 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM73405.1 - 4e-13 49.2 0.1 7e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM73405.1 - 0.00023 20.7 0.1 0.00047 19.7 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 KFM73405.1 - 0.037 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Peptidase_M24_C PF16188.5 KFM73405.1 - 0.086 12.9 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 HTH_psq PF05225.16 KFM73405.1 - 0.16 11.7 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain zf-C2H2 PF00096.26 KFM73406.1 - 1e-19 69.8 23.3 6.7e-06 26.3 0.4 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM73406.1 - 1.3e-17 63.4 20.8 1.8e-07 31.2 0.2 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM73406.1 - 9.3e-14 51.0 20.5 0.0077 17.0 0.2 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFM73406.1 - 0.0011 19.1 8.2 0.55 10.3 0.2 3.2 1 1 1 3 3 3 2 Aberrant zinc-finger zf-TRAF PF02176.18 KFM73406.1 - 0.0034 18.0 12.5 1.8 9.3 0.1 3.2 1 1 2 3 3 3 2 TRAF-type zinc finger Transpos_assoc PF13963.6 KFM73406.1 - 0.0041 17.4 5.2 0.24 11.7 0.1 3.1 2 1 2 4 4 4 1 Transposase-associated domain CHORD PF04968.12 KFM73406.1 - 0.0043 17.7 11.2 4 8.2 2.3 3.7 1 1 3 4 4 4 1 CHORD zinc_ribbon_9 PF14369.6 KFM73406.1 - 0.0077 16.5 2.4 0.68 10.2 0.1 3.2 3 0 0 3 3 3 1 zinc-ribbon Raffinose_syn PF05691.12 KFM73406.1 - 0.008 14.0 0.0 0.0092 13.8 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 IBR PF01485.21 KFM73406.1 - 0.01 16.1 7.6 0.01 16.0 1.5 2.7 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 KFM73406.1 - 0.014 15.6 12.0 3.1 8.2 0.4 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CCAP PF11105.8 KFM73406.1 - 0.015 15.2 4.6 0.28 11.1 0.7 2.2 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-CGNR PF11706.8 KFM73406.1 - 0.016 15.1 6.6 2 8.3 0.1 3.5 4 0 0 4 4 4 0 CGNR zinc finger zf-C2H2_11 PF16622.5 KFM73406.1 - 0.039 13.7 7.2 1.3 8.9 0.4 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KFM73406.1 - 0.1 12.2 3.6 1.1 8.9 0.2 3.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KFM73406.1 - 0.11 12.8 7.1 1.4 9.2 1.0 2.9 1 1 2 3 3 3 0 C2H2-type zinc ribbon XPA_N PF01286.18 KFM73406.1 - 0.28 11.3 4.6 1.1 9.3 0.1 3.1 4 0 0 4 4 3 0 XPA protein N-terminal zf-LYAR PF08790.11 KFM73406.1 - 0.43 10.5 5.8 70 3.5 0.1 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger FOXP-CC PF16159.5 KFM73406.1 - 1.4 9.6 8.8 7.2 7.3 1.9 3.0 3 1 0 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 KFM73406.1 - 4.3 7.8 11.1 3 8.4 0.3 3.5 4 0 0 4 4 3 0 Zinc-finger of C2H2 type DUF629 PF04780.12 KFM73406.1 - 6.3 5.2 6.5 6.8 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Chitin_synth_2 PF03142.15 KFM73408.1 - 1.4e-28 99.8 8.1 8.5e-26 90.6 0.3 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFM73408.1 - 2e-12 47.4 6.5 1.3e-11 44.7 6.5 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFM73408.1 - 1e-08 35.4 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1129 PF06570.11 KFM73408.1 - 3.9 6.9 11.8 0.27 10.7 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Pkinase PF00069.25 KFM73409.1 - 4.7e-15 55.7 0.0 6.1e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73409.1 - 8.3e-07 28.5 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM73410.1 - 2.2e-41 142.0 0.5 3.5e-41 141.3 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73410.1 - 2.9e-27 95.6 1.0 4.8e-27 94.9 1.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM73410.1 - 0.00013 21.0 0.1 0.00013 21.0 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFM73410.1 - 0.0031 17.5 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM73410.1 - 0.018 14.4 0.1 0.072 12.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KFM73410.1 - 0.064 12.6 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM73410.1 - 0.56 9.8 7.3 0.037 13.6 1.3 2.1 2 1 0 2 2 2 0 RIO1 family Det1 PF09737.9 KFM73412.1 - 3e-189 629.3 6.0 3.7e-189 629.0 6.0 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 ELP6 PF09807.9 KFM73413.1 - 2.2e-31 109.2 9.5 2.6e-31 108.9 9.5 1.0 1 0 0 1 1 1 1 Elongation complex protein 6 DDE_1 PF03184.19 KFM73415.1 - 0.0024 17.5 0.1 0.0025 17.5 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM73416.1 - 1.3e-50 167.7 75.5 3.7e-09 36.6 0.5 11.8 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73416.1 - 6.7e-40 133.4 90.5 2.5e-05 24.5 0.4 11.9 12 0 0 12 12 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73416.1 - 7.9e-29 97.9 88.6 0.0016 19.1 0.2 12.4 13 0 0 13 13 13 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM73416.1 - 1.5e-21 76.1 45.7 4e-05 23.8 0.7 11.1 8 2 2 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM73416.1 - 8.5e-21 73.7 70.1 3.8e-05 23.9 0.1 12.1 12 0 0 12 12 12 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM73416.1 - 6.2e-19 67.5 89.0 9.5e-05 22.3 0.9 12.1 13 0 0 13 13 12 9 C2H2-type zinc finger DUF3268 PF11672.8 KFM73416.1 - 0.013 15.8 24.6 0.095 13.0 2.3 5.1 4 1 1 5 5 5 0 zinc-finger-containing domain zf-C2H2_2 PF12756.7 KFM73416.1 - 0.019 15.3 67.9 2.2 8.7 2.0 10.0 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) DUF4428 PF14471.6 KFM73416.1 - 0.034 14.1 0.4 0.034 14.1 0.4 6.7 7 1 0 7 7 7 0 Domain of unknown function (DUF4428) Ta0938 PF11494.8 KFM73416.1 - 0.045 14.0 18.9 0.077 13.3 0.0 6.0 2 2 5 8 8 8 0 Ta0938 zf_UBZ PF18439.1 KFM73416.1 - 0.24 11.0 41.2 0.63 9.7 0.0 10.0 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KFM73416.1 - 0.54 11.1 47.8 0.37 11.6 3.1 6.1 1 1 5 7 7 7 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM73416.1 - 1.9 8.7 42.8 0.24 11.6 1.4 8.0 7 1 1 8 8 8 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFM73416.1 - 2 8.4 0.0 2 8.4 0.0 9.2 11 0 0 11 11 11 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM73416.1 - 4.1 7.1 37.7 3.9 7.2 0.2 8.2 5 2 3 8 8 8 0 MYST family zinc finger domain DUF2115 PF09888.9 KFM73417.1 - 0.017 15.6 0.1 0.019 15.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DDE_3 PF13358.6 KFM73418.1 - 4.5e-07 29.7 0.0 4.5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease p450 PF00067.22 KFM73419.1 - 6.5e-22 77.9 0.0 7.6e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4006 PF13179.6 KFM73419.1 - 0.0078 16.1 0.2 0.014 15.2 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF4006) p450 PF00067.22 KFM73420.1 - 1.8e-48 165.5 1.8 6.8e-48 163.5 1.8 1.7 1 1 0 1 1 1 1 Cytochrome P450 RPT PF13446.6 KFM73420.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein oligo_HPY PF08352.12 KFM73420.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region p450 PF00067.22 KFM73421.1 - 1.1e-40 139.8 0.5 1.3e-40 139.6 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM73422.1 - 8.3e-11 41.3 0.0 9.6e-11 41.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M13 PF01431.21 KFM73424.1 - 0.087 12.4 0.0 0.087 12.4 0.0 1.0 1 0 0 1 1 1 0 Peptidase family M13 zf-H2C2_2 PF13465.6 KFM73425.1 - 2.1e-61 201.8 56.5 4.6e-09 36.3 0.7 9.1 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73425.1 - 9.2e-45 148.7 69.1 3e-07 30.5 1.8 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73425.1 - 7.7e-31 104.1 63.9 8e-05 23.2 1.2 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM73425.1 - 2.2e-27 94.6 66.1 1.7e-05 25.1 1.1 8.3 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM73425.1 - 9.7e-19 66.8 47.0 0.00015 21.4 2.0 7.7 8 0 0 8 8 8 6 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM73425.1 - 1e-18 67.1 49.0 0.0021 18.3 0.5 8.3 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM73425.1 - 1.3e-15 56.8 45.2 0.0032 17.2 0.4 8.9 9 0 0 9 9 8 6 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM73425.1 - 9e-15 54.3 56.9 0.021 14.8 1.8 8.3 8 0 0 8 8 8 8 C2H2-type zinc finger BolA PF01722.18 KFM73425.1 - 6.7e-11 42.3 14.7 0.1 12.9 0.0 6.7 1 1 5 6 6 6 4 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM73425.1 - 1.1e-07 31.7 26.4 2.4 8.3 0.1 8.0 2 2 6 8 8 8 2 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM73425.1 - 1.3e-07 31.6 34.2 1.4 9.1 0.3 8.4 8 0 0 8 8 8 2 DBF zinc finger DZR PF12773.7 KFM73425.1 - 1.5e-07 31.3 20.9 0.13 12.3 0.6 4.4 4 0 0 4 4 4 4 Double zinc ribbon DUF2256 PF10013.9 KFM73425.1 - 2.5e-07 30.7 27.5 3.2 7.9 0.1 8.1 8 0 0 8 8 8 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFM73425.1 - 3.9e-07 29.8 37.9 0.72 9.8 0.5 8.2 8 0 0 8 8 8 5 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM73425.1 - 2.7e-05 24.2 38.0 0.069 13.3 8.5 3.4 1 1 2 3 3 3 3 Putative ribonucleoprotein zinc-finger pf C4 type GAGA PF09237.11 KFM73425.1 - 4.5e-05 23.2 10.8 0.26 11.1 0.2 5.4 2 1 4 6 6 6 2 GAGA factor zf-C2H2_9 PF16293.5 KFM73425.1 - 9.2e-05 22.2 37.7 0.89 9.4 0.3 7.9 1 1 7 8 8 8 1 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 KFM73425.1 - 0.00024 21.1 35.9 5.8 7.1 0.1 7.8 1 1 6 7 7 7 0 KIAA1045 RING finger Tox-HNH-HHH PF15637.6 KFM73425.1 - 0.00037 20.6 2.1 3.6 7.8 0.1 3.8 1 1 3 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF952 PF06108.12 KFM73425.1 - 0.00054 19.9 0.2 1.4 8.9 0.0 4.2 1 1 3 5 5 5 1 Protein of unknown function (DUF952) zf-MYST PF17772.1 KFM73425.1 - 0.00087 18.8 37.6 0.72 9.5 0.3 7.7 2 2 6 8 8 8 3 MYST family zinc finger domain zf-C2H2_2 PF12756.7 KFM73425.1 - 0.01 16.2 58.3 1.5 9.2 1.4 7.9 1 1 6 7 7 6 0 C2H2 type zinc-finger (2 copies) YyzF PF14116.6 KFM73425.1 - 0.019 15.0 24.6 18 5.4 0.1 7.9 8 0 0 8 8 8 0 YyzF-like protein zinc-ribbons_6 PF07191.12 KFM73425.1 - 0.043 13.8 35.8 10 6.2 2.5 6.1 1 1 3 4 4 4 0 zinc-ribbons zinc_ribbon_15 PF17032.5 KFM73425.1 - 0.048 14.4 37.8 0.38 11.5 2.4 4.8 1 1 5 6 6 6 0 zinc-ribbon family FYVE PF01363.21 KFM73425.1 - 0.068 13.3 45.8 0.93 9.7 10.3 5.6 1 1 4 5 5 5 0 FYVE zinc finger C5HCH PF17982.1 KFM73425.1 - 0.13 12.5 28.7 37 4.6 0.1 7.7 7 1 0 8 8 8 0 NSD Cys-His rich domain AMP_N PF05195.16 KFM73425.1 - 0.15 11.8 0.1 41 3.9 0.0 3.4 2 1 2 4 4 4 0 Aminopeptidase P, N-terminal domain Zn-C2H2_12 PF18112.1 KFM73425.1 - 0.38 11.3 42.1 6.7 7.3 0.3 8.3 8 0 0 8 8 8 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_UBOX PF13445.6 KFM73425.1 - 0.56 10.3 18.4 89 3.2 0.0 7.5 8 0 0 8 8 8 0 RING-type zinc-finger IGPD PF00475.18 KFM73425.1 - 0.61 10.4 5.9 6.7 7.0 0.2 3.2 3 1 0 3 3 3 0 Imidazoleglycerol-phosphate dehydratase C1_4 PF07975.12 KFM73425.1 - 0.67 10.2 44.3 3.8 7.8 4.8 6.1 1 1 7 8 8 8 0 TFIIH C1-like domain ADK_lid PF05191.14 KFM73425.1 - 1.6 8.8 31.5 0.91 9.6 0.7 5.1 4 2 1 5 5 5 0 Adenylate kinase, active site lid zf_UBZ PF18439.1 KFM73425.1 - 2.6 7.7 35.4 17 5.1 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger F-box-like_2 PF13013.6 KFM73425.1 - 3.7 7.6 7.3 31 4.6 1.1 3.3 1 1 1 2 2 2 0 F-box-like domain zf-FCS PF06467.14 KFM73425.1 - 7.2 6.6 39.5 15 5.7 0.3 7.9 6 2 2 8 8 8 0 MYM-type Zinc finger with FCS sequence motif zf-trcl PF13451.6 KFM73425.1 - 7.7 6.5 30.3 34 4.4 0.1 7.7 8 0 0 8 8 8 0 Probable zinc-ribbon domain zf-HIT PF04438.16 KFM73425.1 - 8.7 6.3 37.7 11 6.0 1.3 7.9 8 0 0 8 8 8 0 HIT zinc finger Mga PF05043.13 KFM73425.1 - 9.5 6.9 7.8 69 4.1 0.1 3.4 3 2 1 4 4 4 0 Mga helix-turn-helix domain zf-H2C2_2 PF13465.6 KFM73426.1 - 3.2e-61 201.2 61.8 1.9e-08 34.4 0.6 10.1 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73426.1 - 2.2e-42 141.2 86.5 1.1e-06 28.8 0.9 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73426.1 - 1.2e-32 109.7 79.4 0.00051 20.7 1.0 10.2 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFM73426.1 - 1.7e-28 98.1 74.6 3.8e-05 23.9 0.9 10.4 9 1 1 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM73426.1 - 5.2e-18 64.8 52.9 0.018 15.3 1.7 10.3 9 1 1 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM73426.1 - 8.5e-15 54.2 32.9 0.0052 16.5 0.3 8.6 8 1 0 8 8 8 6 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM73426.1 - 1.7e-08 34.3 69.6 0.14 12.2 0.9 10.6 10 0 0 10 10 10 6 C2H2-type zinc finger BolA PF01722.18 KFM73426.1 - 6.3e-08 32.8 13.8 0.24 11.7 0.4 6.3 1 1 5 6 6 6 4 BolA-like protein zf-DBF PF07535.12 KFM73426.1 - 6.4e-07 29.4 42.7 3.8 7.7 0.6 9.4 8 1 1 9 9 9 3 DBF zinc finger zf-C2HC_2 PF13913.6 KFM73426.1 - 0.00017 21.4 44.6 0.74 9.8 0.4 9.4 10 0 0 10 10 10 5 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFM73426.1 - 0.00058 19.6 58.3 0.0089 15.8 0.8 8.8 9 0 0 9 9 9 4 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM73426.1 - 0.0007 19.6 34.8 0.51 10.4 0.1 8.7 7 1 2 9 9 9 2 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM73426.1 - 0.0038 17.0 40.8 1.6 8.6 0.2 9.0 2 2 8 10 10 10 2 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM73426.1 - 0.014 15.5 44.1 0.35 11.0 2.3 4.4 1 1 2 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 KFM73426.1 - 0.033 14.1 56.4 0.72 9.8 4.3 6.7 1 1 6 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 KFM73426.1 - 0.056 13.6 57.1 0.053 13.7 11.5 6.4 1 1 3 4 4 4 0 FYVE zinc finger Zf_RING PF16744.5 KFM73426.1 - 0.21 11.7 49.5 5.5 7.2 6.9 8.6 2 1 6 8 8 8 0 KIAA1045 RING finger ADK_lid PF05191.14 KFM73426.1 - 0.67 10.0 37.5 3.4 7.7 4.0 7.4 4 4 3 7 7 7 0 Adenylate kinase, active site lid C5HCH PF17982.1 KFM73426.1 - 2.6 8.3 44.8 18 5.5 0.0 9.0 6 1 3 9 9 9 0 NSD Cys-His rich domain YyzF PF14116.6 KFM73426.1 - 3.7 7.7 33.9 27 4.9 0.2 8.9 9 1 0 9 9 9 0 YyzF-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM73427.1 - 4.4e-16 58.9 3.5 5.6e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73427.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73427.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73427.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73427.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM73428.1 - 0.0019 18.0 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM73429.1 - 3.1e-30 105.6 0.5 6e-30 104.6 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM73429.1 - 1.4e-09 37.6 0.2 4.9e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IFT57 PF10498.9 KFM73429.1 - 0.043 12.8 7.6 0.055 12.4 0.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MAT1 PF06391.13 KFM73429.1 - 2.7 7.8 7.7 2.6 7.8 2.0 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Exonuc_VII_L PF02601.15 KFM73429.1 - 4 6.9 6.9 6.3 6.3 1.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1057 PF06342.12 KFM73430.1 - 1.8e-07 30.5 0.0 2.1e-07 30.3 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Torsin PF06309.11 KFM73430.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Torsin DUF1759 PF03564.15 KFM73431.1 - 1e-35 122.8 0.5 1.7e-35 122.1 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM73431.1 - 0.00033 20.5 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Aminotran_1_2 PF00155.21 KFM73433.1 - 1.2e-49 169.5 0.0 1.4e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFM73433.1 - 0.2 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFM73434.1 - 9e-50 169.8 0.0 1.1e-49 169.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_Tnp_Tc3_2 PF01498.18 KFM73435.1 - 1.9e-17 63.2 1.3 6.4e-16 58.4 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73435.1 - 1.4e-13 50.8 0.0 2.6e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Aminotran_1_2 PF00155.21 KFM73436.1 - 8.1e-49 166.7 0.0 1e-48 166.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Rab_bind PF16704.5 KFM73437.1 - 2e-15 56.5 4.4 2e-15 56.5 4.4 5.5 5 0 0 5 5 5 1 Rab binding domain GRIP PF01465.20 KFM73437.1 - 3.8e-13 49.1 0.4 1.3e-12 47.4 0.4 2.1 1 0 0 1 1 1 1 GRIP domain Tup_N PF08581.10 KFM73437.1 - 0.0036 17.6 9.0 0.0036 17.6 9.0 17.8 11 3 6 18 18 18 2 Tup N-terminal DUF2968 PF11180.8 KFM73437.1 - 0.0088 15.7 1.6 0.0088 15.7 1.6 12.6 7 3 7 14 14 14 1 Protein of unknown function (DUF2968) PPO1_DWL PF12142.8 KFM73437.1 - 0.031 14.0 0.2 0.13 12.1 0.2 2.1 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Mce4_CUP1 PF11887.8 KFM73437.1 - 0.26 10.7 4.2 0.25 10.8 0.6 3.0 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative WD40 PF00400.32 KFM73438.1 - 1.5e-39 133.2 23.3 6.6e-07 29.9 0.0 7.8 8 0 0 8 8 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 KFM73438.1 - 2.1e-17 62.7 2.2 4e-17 61.8 2.2 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 KFM73438.1 - 1.2e-11 44.8 2.1 0.0016 18.7 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KFM73438.1 - 5.4e-10 39.0 0.4 1.3e-09 37.8 0.1 1.8 2 0 0 2 2 1 1 F-box-like WD40_like PF17005.5 KFM73438.1 - 4.2e-08 32.9 1.6 8.9e-05 22.0 1.1 2.2 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 KFM73438.1 - 2.2e-07 29.9 8.1 0.053 12.2 0.1 4.8 1 1 2 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.33 KFM73438.1 - 1.2e-06 28.2 0.1 2.6e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain eIF2A PF08662.11 KFM73438.1 - 0.0038 17.1 0.1 0.47 10.3 0.1 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF5046 PF16465.5 KFM73438.1 - 0.0072 15.8 0.2 33 3.8 0.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF5046) DUF4508 PF14969.6 KFM73438.1 - 0.0083 16.4 0.2 0.022 15.0 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4508) F-box_5 PF18511.1 KFM73438.1 - 0.016 14.8 0.3 0.052 13.1 0.3 1.9 1 1 0 1 1 1 0 F-box DUF1513 PF07433.11 KFM73438.1 - 0.09 11.8 0.0 4.1 6.4 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) 120_Rick_ant PF12574.8 KFM73438.1 - 0.13 11.4 0.1 0.83 8.8 0.0 1.9 1 1 1 2 2 2 0 120 KDa Rickettsia surface antigen DAGK_cat PF00781.24 KFM73440.1 - 1.6e-26 92.4 0.0 2.4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFM73440.1 - 4.7e-22 77.6 24.5 2.7e-11 43.2 8.4 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFM73440.1 - 1.4e-06 28.5 14.0 0.00028 21.2 3.2 2.7 2 0 0 2 2 2 2 C1 domain DAGK_acc PF00609.19 KFM73442.1 - 3.4e-31 108.7 0.0 5.3e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain SAM_1 PF00536.30 KFM73442.1 - 4.1e-19 68.8 0.3 9.2e-19 67.6 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM73442.1 - 1e-17 63.9 0.1 2.3e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 KFM73442.1 - 0.033 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF229 PF02995.17 KFM73443.1 - 1.7e-116 389.8 1.2 2.1e-116 389.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 KFM73443.1 - 3.8e-05 23.2 0.0 0.00026 20.5 0.0 2.0 2 0 0 2 2 2 1 Sulfatase Ycf66_N PF07444.11 KFM73445.1 - 0.096 12.8 1.3 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 Ycf66 protein N-terminus DUF4728 PF15860.5 KFM73445.1 - 0.12 13.0 4.9 0.15 12.8 3.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4728) Neur_chan_LBD PF02931.23 KFM73446.1 - 1.1e-11 44.6 0.2 1.3e-11 44.4 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFM73448.1 - 9e-09 35.1 0.0 9.9e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM73449.1 - 6.2e-27 95.2 0.2 2.3e-26 93.3 0.2 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region 7tm_1 PF00001.21 KFM73450.1 - 4.6e-10 39.3 0.3 4.6e-10 39.3 0.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFM73450.1 - 0.016 15.0 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor HTH_Tnp_Tc3_2 PF01498.18 KFM73452.1 - 2.2e-16 59.9 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73452.1 - 8.6e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3342 PF11822.8 KFM73454.1 - 2.2e-14 53.4 0.0 3e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.31 KFM73454.1 - 6.6e-05 23.1 0.1 7.7e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM73454.1 - 0.083 13.0 0.1 0.6 10.2 0.1 1.9 2 0 0 2 2 2 0 BTB And C-terminal Kelch DUF2182 PF09948.9 KFM73454.1 - 0.14 12.0 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) PAP2 PF01569.21 KFM73456.1 - 2.3e-15 56.6 5.9 2.3e-15 56.6 5.9 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFM73456.1 - 0.11 12.1 16.3 1.6 8.4 16.3 2.5 1 1 0 1 1 1 0 PAP2 superfamily bZIP_1 PF00170.21 KFM73457.1 - 9.8e-12 44.8 14.9 1.4e-11 44.3 14.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM73457.1 - 3.1e-07 30.4 15.3 4.6e-07 29.8 15.3 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFM73457.1 - 1.1e-05 25.9 13.0 1.2e-05 25.7 12.1 1.5 1 1 1 2 2 2 1 bZIP Maf transcription factor Fungal_TACC PF12709.7 KFM73457.1 - 0.063 13.7 2.2 0.11 12.9 2.2 1.4 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1088 PF06469.11 KFM73457.1 - 0.3 10.8 4.5 0.46 10.2 4.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) RasGEF_N PF00618.20 KFM73458.1 - 8.1e-18 64.6 0.2 1.6e-17 63.7 0.2 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.19 KFM73458.1 - 2.5e-10 40.9 0.0 4.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF PF00617.19 KFM73459.1 - 6.7e-09 36.2 0.0 1.2e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RA PF00788.23 KFM73461.1 - 9e-13 48.7 0.0 1.2e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Mtc PF03820.17 KFM73463.1 - 3.4e-140 466.5 0.0 3.8e-140 466.3 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier HTH_Tnp_Tc3_2 PF01498.18 KFM73464.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73464.1 - 1.4e-11 44.4 0.0 2.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73466.1 - 1.9e-16 60.1 2.2 4.2e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73466.1 - 7.6e-13 48.5 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM73467.1 - 9.2e-13 48.2 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Sulfotransfer_1 PF00685.27 KFM73468.1 - 2.5e-32 112.4 0.0 3.3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM73468.1 - 4.1e-14 53.5 0.0 5e-10 40.1 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFM73468.1 - 0.0061 16.5 0.0 0.034 14.1 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family Fasciclin PF02469.22 KFM73469.1 - 3.2e-20 72.6 0.2 4.4e-20 72.2 0.2 1.1 1 0 0 1 1 1 1 Fasciclin domain ING PF12998.7 KFM73469.1 - 0.1 13.2 2.4 0.17 12.5 2.4 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding EMI PF07546.13 KFM73470.1 - 0.052 14.3 2.2 0.11 13.3 2.2 1.6 1 0 0 1 1 1 0 EMI domain Stathmin PF00836.19 KFM73471.1 - 2.3e-45 153.9 58.5 8.1e-33 113.3 15.2 3.8 1 1 3 4 4 4 4 Stathmin family DUF883 PF05957.13 KFM73471.1 - 0.28 11.8 23.2 0.21 12.2 1.6 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) P53_C PF11619.8 KFM73471.1 - 1.8 8.7 7.7 9.9 6.3 1.8 3.3 1 1 0 2 2 2 0 Transcription factor P53 - C terminal domain Glyco_hydro_52 PF03512.13 KFM73474.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 Aminotran_5 PF00266.19 KFM73475.1 - 0.0014 17.7 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V HEM4 PF02602.15 KFM73475.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Aminotran_5 PF00266.19 KFM73476.1 - 1.1e-22 80.6 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V HTH_Tnp_Tc3_2 PF01498.18 KFM73477.1 - 2.2e-16 59.8 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73477.1 - 2.9e-14 53.1 0.0 4.6e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73478.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73478.1 - 9.4e-14 51.4 0.0 2.2e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73478.1 - 1.9e-07 30.7 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73478.1 - 0.0024 17.6 0.6 0.0076 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73478.1 - 0.028 14.5 0.4 0.091 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM73478.1 - 2 9.1 15.6 0.12 13.0 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73479.1 - 4.2e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73479.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73479.1 - 1.7e-07 30.8 1.2 6.6e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73479.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73479.1 - 0.022 14.8 0.4 0.085 13.0 0.4 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM73479.1 - 2 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain TSP_C PF05735.12 KFM73480.1 - 8.9e-100 332.6 0.3 1.1e-99 332.3 0.3 1.1 1 0 0 1 1 1 1 Thrombospondin C-terminal region PID PF00640.23 KFM73481.1 - 1.9e-34 118.7 0.1 3.5e-34 117.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 KFM73481.1 - 6.5e-28 96.9 7.1 1.6e-13 50.8 0.4 2.7 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KFM73481.1 - 4.9e-17 61.5 1.5 2.3e-07 30.6 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFM73481.1 - 3.3e-07 30.5 0.1 3.2e-05 24.2 0.0 2.5 1 1 1 2 2 2 1 PDZ domain NRho PF16733.5 KFM73481.1 - 0.0012 18.9 0.2 0.0044 17.0 0.1 2.0 2 0 0 2 2 2 1 Rhomboid N-terminal domain Tricorn_PDZ PF14685.6 KFM73481.1 - 0.0087 16.0 1.2 2.9 7.9 0.0 2.8 3 0 0 3 3 3 2 Tricorn protease PDZ domain DUF1435 PF07256.12 KFM73481.1 - 0.15 12.2 0.1 0.41 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) PRKCSH-like PF12999.7 KFM73482.1 - 1.7e-39 135.5 9.2 1.7e-39 135.5 9.2 3.0 2 1 1 3 3 3 1 Glucosidase II beta subunit-like EF-hand_1 PF00036.32 KFM73482.1 - 2.5e-07 29.7 1.3 0.0099 15.4 0.4 2.7 1 1 1 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM73482.1 - 6.8e-06 25.6 0.9 0.063 13.2 0.3 2.7 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFM73482.1 - 3.6e-05 23.1 6.2 0.0013 18.1 1.1 3.2 2 1 1 3 3 3 2 EF hand Ldl_recept_a PF00057.18 KFM73482.1 - 0.00035 20.7 18.5 0.0045 17.2 2.5 2.6 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A EF-hand_7 PF13499.6 KFM73482.1 - 0.0067 16.8 10.0 0.053 14.0 1.2 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KFM73482.1 - 0.017 14.9 0.6 0.13 12.1 0.2 2.4 1 1 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM73482.1 - 0.94 9.8 9.2 6.9 7.0 8.7 2.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Ank PF00023.30 KFM73483.1 - 1.5e-11 44.2 0.7 0.00019 21.8 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFM73483.1 - 1.8e-09 38.1 0.2 0.00033 21.2 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM73483.1 - 2.5e-09 37.5 0.4 6.4e-05 23.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM73483.1 - 2.7e-06 27.3 0.2 0.00026 21.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KFM73483.1 - 6.7e-05 23.1 0.6 0.11 12.8 0.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HTH_3 PF01381.22 KFM73483.1 - 0.13 12.3 0.2 0.26 11.3 0.2 1.6 1 1 0 1 1 1 0 Helix-turn-helix C2 PF00168.30 KFM73484.1 - 2.4e-57 191.6 0.5 8.5e-30 103.1 0.1 2.2 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 KFM73484.1 - 0.00048 19.7 0.1 0.21 11.2 0.0 2.5 1 1 1 2 2 2 2 CEP76 C2 domain Comm PF15957.5 KFM73484.1 - 0.016 15.5 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Commissureless DOCK-C2 PF14429.6 KFM73484.1 - 0.028 14.2 0.1 3.9 7.2 0.1 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Shisa PF13908.6 KFM73484.1 - 0.03 14.6 0.3 0.054 13.7 0.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PTEN_C2 PF10409.9 KFM73484.1 - 0.033 14.0 0.8 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein TMEM52 PF14979.6 KFM73484.1 - 0.052 13.5 3.2 0.14 12.1 3.2 1.7 1 0 0 1 1 1 0 Transmembrane 52 Transglut_C PF00927.22 KFM73484.1 - 0.12 12.5 0.5 7.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Herpes_gE PF02480.16 KFM73484.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MAP17 PF15807.5 KFM73484.1 - 0.39 10.9 2.6 1.2 9.4 2.6 1.8 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMIE PF16038.5 KFM73484.1 - 2.3 8.1 10.3 1.2 9.1 6.9 2.2 2 0 0 2 2 2 0 TMIE protein UEV PF05743.13 KFM73485.1 - 1.1e-44 151.2 0.7 2e-44 150.3 0.1 1.8 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.10 KFM73485.1 - 8.2e-25 86.5 1.6 2.8e-24 84.8 0.0 2.2 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 KFM73485.1 - 0.00066 19.3 0.3 0.0018 17.9 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PL48 PF15903.5 KFM73485.1 - 0.014 14.4 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 Fmp27_WPPW PF10359.9 KFM73485.1 - 0.03 13.2 5.2 0.041 12.8 5.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Exonuc_VII_L PF02601.15 KFM73485.1 - 0.068 12.7 2.3 0.094 12.3 2.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc29 PF17082.5 KFM73485.1 - 0.071 12.9 2.6 0.13 12.1 2.6 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 Herpes_UL6 PF01763.16 KFM73485.1 - 0.079 11.5 4.3 0.11 10.9 4.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF3450 PF11932.8 KFM73485.1 - 0.22 10.8 8.4 0.34 10.2 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cortex-I_coil PF09304.10 KFM73485.1 - 0.28 11.4 10.5 0.6 10.4 10.5 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil FapA PF03961.13 KFM73485.1 - 0.36 9.4 7.8 0.56 8.8 7.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 KFM73485.1 - 0.36 11.1 13.6 0.68 10.2 13.6 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding RasGAP_C PF03836.15 KFM73485.1 - 0.39 10.9 8.9 1.1 9.5 8.9 1.7 1 1 0 1 1 1 0 RasGAP C-terminus DUF1664 PF07889.12 KFM73485.1 - 0.51 10.4 5.9 1.3 9.1 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KFM73485.1 - 0.74 8.6 12.3 1.3 7.9 12.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DHquinase_II PF01220.19 KFM73485.1 - 0.77 9.4 2.6 1.6 8.4 2.3 1.5 1 1 0 1 1 1 0 Dehydroquinase class II LMBR1 PF04791.16 KFM73485.1 - 0.91 8.4 2.3 1.3 7.8 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Prefoldin_2 PF01920.20 KFM73485.1 - 1.2 9.1 16.2 0.18 11.8 8.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit Prominin PF05478.11 KFM73485.1 - 1.7 6.5 5.6 2.3 6.0 5.6 1.1 1 0 0 1 1 1 0 Prominin APG6_N PF17675.1 KFM73485.1 - 3.4 8.2 13.2 6.8 7.2 13.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KFM73485.1 - 5.5 6.8 12.5 2.9 7.7 5.0 2.4 1 1 1 2 2 2 0 Septum formation initiator KxDL PF10241.9 KFM73485.1 - 6.5 7.1 9.1 0.95 9.8 4.0 2.2 2 1 0 2 2 1 0 Uncharacterized conserved protein Spc24 PF08286.11 KFM73485.1 - 9.7 6.5 11.8 2.2 8.5 6.7 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PIP49_C PF12260.8 KFM73487.1 - 0.0022 17.7 0.0 0.0022 17.7 0.0 1.0 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_C PF12260.8 KFM73488.1 - 0.00016 21.4 0.0 0.0002 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 tRNA_bind_3 PF17176.4 KFM73488.1 - 0.019 15.2 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 tRNA-binding domain Ovate PF04844.13 KFM73488.1 - 0.058 13.4 0.3 0.1 12.6 0.3 1.4 1 1 0 1 1 1 0 Transcriptional repressor, ovate Atg14 PF10186.9 KFM73490.1 - 4.1e-08 32.7 0.5 4.1e-08 32.7 0.5 2.1 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KFM73490.1 - 4e-05 22.7 0.2 4e-05 22.7 0.2 2.5 3 0 0 3 3 3 1 Vacuolar protein sorting 38 Homeodomain PF00046.29 KFM73490.1 - 0.13 12.1 1.0 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 Homeodomain COG2 PF06148.11 KFM73491.1 - 0.0076 16.3 9.5 0.087 12.9 2.2 2.1 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 RPW8 PF05659.11 KFM73491.1 - 0.029 14.1 8.8 0.43 10.3 1.1 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Lebercilin PF15619.6 KFM73491.1 - 0.029 14.0 13.0 0.042 13.5 13.0 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Flu_NS2 PF00601.19 KFM73491.1 - 0.031 14.6 3.5 0.047 14.0 3.0 1.6 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) RILP PF11461.8 KFM73491.1 - 0.079 13.2 5.5 0.15 12.3 3.0 2.5 2 1 0 2 2 1 0 Rab interacting lysosomal protein DUF2924 PF11149.8 KFM73491.1 - 0.14 12.5 2.1 0.19 12.1 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) CENP-F_N PF10481.9 KFM73491.1 - 0.18 11.5 13.8 0.066 12.8 7.2 2.0 1 1 1 2 2 2 0 Cenp-F N-terminal domain DUF3450 PF11932.8 KFM73491.1 - 0.37 10.0 10.6 0.041 13.2 5.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FAM76 PF16046.5 KFM73491.1 - 0.39 10.0 10.4 0.59 9.4 10.3 1.3 1 1 0 1 1 1 0 FAM76 protein UPF0242 PF06785.11 KFM73491.1 - 0.59 10.2 13.4 1.4 9.0 13.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ECM11 PF15463.6 KFM73491.1 - 0.92 10.1 8.3 2.8 8.5 1.1 2.4 3 0 0 3 3 2 0 Extracellular mutant protein 11 FliD_C PF07195.12 KFM73491.1 - 1.1 8.7 7.1 4.6 6.6 1.5 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Phage_GPO PF05929.11 KFM73491.1 - 1.7 8.2 6.0 0.56 9.8 2.0 1.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.9 KFM73491.1 - 1.9 7.5 13.3 3.5 6.6 13.3 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KFM73491.1 - 3 7.9 7.2 5.8 7.0 2.8 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 KFM73491.1 - 3.5 8.3 13.0 1.6 9.4 4.8 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 KFM73491.1 - 6.1 7.1 11.2 6.2 7.1 3.0 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain VPS38 PF17649.1 KFM73492.1 - 0.00094 18.2 0.1 0.00099 18.1 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 38 Pkinase PF00069.25 KFM73493.1 - 4.8e-73 245.8 0.0 6.7e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73493.1 - 2.6e-46 158.0 0.0 4.1e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFM73493.1 - 2.3e-25 88.7 0.1 6.3e-25 87.3 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KFM73493.1 - 9e-06 24.7 0.0 2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM73493.1 - 3.8e-05 23.2 0.0 0.0016 17.8 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KFM73493.1 - 0.0069 16.3 0.0 2.8 7.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFM73493.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4806 PF16064.5 KFM73494.1 - 9.4e-12 45.1 0.0 1.9e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4806) HTH_Tnp_Tc3_2 PF01498.18 KFM73494.1 - 0.036 14.3 0.6 12 6.2 0.0 2.9 2 1 0 2 2 2 0 Transposase Med26_M PF15694.5 KFM73495.1 - 0.024 14.7 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain DDE_3 PF13358.6 KFM73496.1 - 1.3e-05 25.0 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73497.1 - 3.5e-15 56.0 2.7 6.5e-15 55.1 2.7 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73497.1 - 8e-14 51.6 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ANF_receptor PF01094.28 KFM73499.1 - 3.1e-72 243.6 0.3 3.8e-72 243.4 0.3 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KFM73499.1 - 6.3e-10 39.2 0.1 8.7e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein HTH_Tnp_Tc3_2 PF01498.18 KFM73500.1 - 2.3e-16 59.8 2.2 4.2e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73500.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73501.1 - 4.7e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73501.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73501.1 - 1.9e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73501.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73501.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Hemocyanin_C PF03723.14 KFM73502.1 - 3.4e-68 229.7 0.1 4.2e-68 229.4 0.1 1.1 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_M PF00372.19 KFM73502.1 - 2.3e-22 79.5 0.0 3.7e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Tyrosinase PF00264.20 KFM73502.1 - 2.1e-07 31.5 0.1 3.5e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Hemocyanin_M PF00372.19 KFM73503.1 - 5.9e-73 245.4 0.0 8.1e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Hemocyanin_C PF03723.14 KFM73503.1 - 1.2e-68 231.1 0.0 1.6e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_N PF03722.14 KFM73503.1 - 4.2e-22 79.0 0.0 1e-21 77.7 0.0 1.6 1 0 0 1 1 1 1 Hemocyanin, all-alpha domain Tyrosinase PF00264.20 KFM73503.1 - 5.4e-08 33.4 0.6 9e-08 32.7 0.6 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase cNMP_binding PF00027.29 KFM73504.1 - 4e-21 74.9 0.0 6e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RIIa PF02197.17 KFM73504.1 - 1.5e-07 30.9 0.0 3.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Orn_DAP_Arg_deC PF00278.22 KFM73504.1 - 0.012 15.9 0.1 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Strep_SA_rep PF06696.11 KFM73505.1 - 0.01 15.8 4.6 1.1 9.3 0.1 4.0 2 1 2 4 4 4 0 Streptococcal surface antigen repeat DUF842 PF05811.13 KFM73505.1 - 0.011 15.5 3.3 0.013 15.1 3.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Apolipoprotein PF01442.18 KFM73505.1 - 0.015 15.2 4.0 0.016 15.0 4.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phasin_2 PF09361.10 KFM73505.1 - 0.015 15.5 4.2 0.021 15.1 4.2 1.3 1 0 0 1 1 1 0 Phasin protein DUF1451 PF07295.11 KFM73505.1 - 0.022 14.8 5.1 0.026 14.5 5.1 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Tox-REase-3 PF15647.6 KFM73505.1 - 0.087 13.1 4.7 0.11 12.7 4.7 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 RNase_H PF00075.24 KFM73506.1 - 0.00021 21.5 0.0 0.00076 19.7 0.0 2.0 1 0 0 1 1 1 1 RNase H zf-CCHC PF00098.23 KFM73507.1 - 6.2e-11 41.9 11.1 3.1e-05 23.8 1.5 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFM73507.1 - 3.9e-10 39.4 11.4 3.1e-05 23.7 2.9 2.5 2 0 0 2 2 2 2 Zinc knuckle gag-asp_proteas PF13975.6 KFM73507.1 - 1.9e-08 34.7 0.0 7.7e-08 32.8 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Apolipoprotein PF01442.18 KFM73507.1 - 1.8e-06 28.0 23.1 1.8e-06 28.0 23.1 2.7 3 1 0 3 3 3 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM73507.1 - 6.2e-06 26.3 6.9 0.0055 16.7 0.3 4.5 3 2 1 5 5 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus Asp_protease_2 PF13650.6 KFM73507.1 - 5e-05 23.9 0.0 0.00018 22.1 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease PNMA PF14893.6 KFM73507.1 - 5.9e-05 22.6 0.1 5.9e-05 22.6 0.1 2.6 2 0 0 2 2 1 1 PNMA Phasin PF05597.11 KFM73507.1 - 9.3e-05 22.4 8.1 9.3e-05 22.4 8.1 4.4 3 1 1 4 4 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) HSBP1 PF06825.12 KFM73507.1 - 0.00039 20.2 1.9 1.7 8.6 0.2 4.0 3 1 1 4 4 4 1 Heat shock factor binding protein 1 zf-CCHC_4 PF14392.6 KFM73507.1 - 0.0023 17.6 5.4 0.26 11.1 0.6 2.6 2 0 0 2 2 2 2 Zinc knuckle DUF1351 PF07083.11 KFM73507.1 - 0.004 16.9 22.5 0.13 12.0 14.4 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1351) DUF1664 PF07889.12 KFM73507.1 - 0.0052 16.8 25.5 0.077 13.0 8.0 3.7 2 2 2 4 4 4 3 Protein of unknown function (DUF1664) DUF1640 PF07798.11 KFM73507.1 - 0.007 16.4 29.7 0.0072 16.4 10.6 3.2 3 2 1 4 4 4 2 Protein of unknown function (DUF1640) NPV_P10 PF05531.12 KFM73507.1 - 0.028 14.9 18.7 1.4 9.4 1.5 6.0 4 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein HalX PF08663.10 KFM73507.1 - 0.041 14.2 6.4 7.5 7.0 0.0 4.5 3 1 1 4 4 4 0 HalX domain HscB_4_cys PF18256.1 KFM73507.1 - 0.041 13.7 12.4 0.57 10.1 3.8 2.5 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Vps36-NZF-N PF16988.5 KFM73507.1 - 0.16 11.4 3.1 2.8 7.4 0.2 3.1 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FAD_SOX PF18371.1 KFM73507.1 - 0.36 11.2 2.7 1 9.7 0.0 3.0 3 1 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase ApoO PF09769.9 KFM73507.1 - 0.44 10.5 8.6 4.6 7.2 2.7 3.5 1 1 1 2 2 2 0 Apolipoprotein O Mu-like_Com PF10122.9 KFM73507.1 - 0.54 9.7 5.3 4.3 6.9 0.8 3.4 3 0 0 3 3 3 0 Mu-like prophage protein Com SF-assemblin PF06705.11 KFM73507.1 - 0.97 8.7 29.1 0.38 10.0 24.4 2.6 2 1 0 2 2 2 0 SF-assemblin/beta giardin zf-ribbon_3 PF13248.6 KFM73507.1 - 1.1 8.7 7.8 1.3 8.5 0.9 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KFM73507.1 - 3.2 7.6 5.5 21 5.0 0.7 3.0 2 0 0 2 2 2 0 zinc-ribbon domain Prominin PF05478.11 KFM73507.1 - 3.4 5.5 23.1 0.063 11.2 9.2 2.6 2 1 1 3 3 3 0 Prominin CdvA PF18822.1 KFM73507.1 - 4 7.3 26.8 3.8 7.4 2.3 5.0 2 1 3 5 5 4 0 CdvA-like coiled-coil domain FliG_M PF14841.6 KFM73507.1 - 4.1 7.7 8.1 5.8 7.2 0.1 3.4 3 1 1 4 4 4 0 FliG middle domain DUF883 PF05957.13 KFM73507.1 - 5.2 7.7 21.6 5.8 7.6 5.1 3.7 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 KFM73507.1 - 5.6 6.2 22.7 5.1 6.4 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) zf-C2H2_10 PF16588.5 KFM73507.1 - 5.8 6.8 9.7 4.2 7.2 0.9 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger ApoLp-III PF07464.11 KFM73507.1 - 9 6.4 31.1 1.9 8.6 19.7 2.9 2 1 1 3 3 2 0 Apolipophorin-III precursor (apoLp-III) HTH_Tnp_Tc3_2 PF01498.18 KFM73508.1 - 4.6e-30 103.7 14.1 2.1e-15 56.7 6.5 2.5 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM73508.1 - 6.8e-16 58.3 0.1 9.6e-15 54.6 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM73508.1 - 4.6e-06 27.2 20.6 0.00085 19.9 2.1 3.5 3 1 0 3 3 3 2 Homeodomain-like domain HTH_23 PF13384.6 KFM73508.1 - 0.00039 20.1 0.3 0.12 12.2 0.1 4.1 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73508.1 - 0.007 16.5 1.5 0.063 13.4 0.2 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM73508.1 - 0.0084 16.1 5.4 0.049 13.7 0.4 3.1 3 0 0 3 3 3 1 Winged helix-turn helix HTH_7 PF02796.15 KFM73508.1 - 0.067 13.3 0.1 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DDE_3 PF13358.6 KFM73509.1 - 8.5e-14 51.5 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73509.1 - 1.4e-09 38.0 0.0 4.1e-08 33.4 0.1 2.3 2 0 0 2 2 2 1 Transposase Pex14_N PF04695.13 KFM73510.1 - 0.0025 18.5 0.1 0.0033 18.1 0.1 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-3 PF04882.12 KFM73510.1 - 0.007 15.4 0.7 0.0084 15.1 0.7 1.0 1 0 0 1 1 1 1 Peroxin-3 HNF-1_N PF04814.13 KFM73510.1 - 0.044 14.4 0.7 0.061 13.9 0.7 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus PBP1_TM PF14812.6 KFM73510.1 - 0.23 11.9 6.7 0.2 12.0 0.6 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CAP PF00188.26 KFM73511.1 - 1.5e-21 77.5 0.1 3.2e-21 76.5 0.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ost5 PF05251.12 KFM73511.1 - 0.027 14.7 0.3 3 8.2 0.3 2.3 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Neur_chan_memb PF02932.16 KFM73512.1 - 5.2e-15 56.2 3.8 6.3e-15 55.9 3.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF1929 PF09118.11 KFM73513.1 - 0.21 11.9 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) HTH_Tnp_Tc3_2 PF01498.18 KFM73514.1 - 1.9e-16 60.1 2.2 6.4e-16 58.4 2.2 2.0 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73514.1 - 1.5e-13 50.7 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73514.1 - 3.3e-07 29.9 1.6 7.8e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73514.1 - 0.0033 17.2 0.6 0.0084 15.9 0.6 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73514.1 - 0.034 14.3 0.4 0.1 12.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM73514.1 - 3.6 8.3 13.9 0.14 12.8 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain PDZ PF00595.24 KFM73515.1 - 1.4e-06 28.5 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM73515.1 - 2.4e-06 27.3 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM73515.1 - 0.00066 19.9 0.0 0.00091 19.5 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Dabb PF07876.12 KFM73516.1 - 0.026 15.1 0.1 0.11 13.1 0.1 2.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Paramyxo_ncap PF00973.19 KFM73516.1 - 0.35 9.7 8.0 0.59 9.0 8.0 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TRCF PF03461.15 KFM73516.1 - 0.39 11.1 5.9 7.9 6.9 0.9 2.6 2 0 0 2 2 2 0 TRCF domain Prominin PF05478.11 KFM73516.1 - 0.63 7.9 6.8 0.92 7.4 6.8 1.2 1 0 0 1 1 1 0 Prominin GAS PF13851.6 KFM73516.1 - 1 8.7 17.3 0.19 11.0 9.8 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3037 PF11236.8 KFM73516.1 - 1.6 9.2 4.1 6.8 7.2 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) DDE_3 PF13358.6 KFM73517.1 - 1.4e-10 41.1 0.0 1.5e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HVSL PF09749.9 KFM73520.1 - 7.9e-53 179.4 0.1 9.9e-53 179.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Tom7 PF08038.12 KFM73521.1 - 1.1e-15 56.9 0.2 1.3e-15 56.7 0.2 1.0 1 0 0 1 1 1 1 TOM7 family Cdc6_C PF09079.11 KFM73522.1 - 6.9e-14 51.6 0.7 1.4e-13 50.6 0.7 1.5 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA PF00004.29 KFM73522.1 - 1.2e-12 48.4 0.2 4.1e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM73522.1 - 9.1e-11 42.2 0.0 5.4e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFM73522.1 - 3.7e-07 30.2 0.0 6.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFM73522.1 - 4.9e-07 30.3 0.1 0.00021 21.7 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KFM73522.1 - 2.2e-06 28.1 0.2 0.00034 21.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KFM73522.1 - 2.8e-05 23.5 0.0 4.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_lid_10 PF17872.1 KFM73522.1 - 3.8e-05 23.7 0.4 3.8e-05 23.7 0.4 2.2 3 0 0 3 3 3 1 AAA lid domain AAA_7 PF12775.7 KFM73522.1 - 0.00018 21.1 0.2 0.00044 19.8 0.3 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 KFM73522.1 - 0.0055 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM73522.1 - 0.0072 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 KFM73522.1 - 0.011 15.2 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 KFM73522.1 - 0.023 15.1 0.1 0.055 13.8 0.1 1.7 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KFM73522.1 - 0.031 13.4 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KFM73522.1 - 0.04 13.6 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFM73522.1 - 0.05 13.4 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KFM73522.1 - 0.092 12.1 0.2 0.2 11.0 0.1 1.6 1 1 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 KFM73522.1 - 0.16 11.7 0.4 1.7 8.3 0.4 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain FYRC PF05965.14 KFM73524.1 - 0.065 13.4 0.1 0.081 13.1 0.1 1.2 1 1 0 1 1 1 0 F/Y rich C-terminus 2-ph_phosp PF04029.14 KFM73524.1 - 0.09 11.9 0.1 0.098 11.8 0.1 1.0 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase PIF1 PF05970.14 KFM73525.1 - 2.3e-54 185.0 0.2 2.6e-54 184.8 0.2 1.0 1 0 0 1 1 1 1 PIF1-like helicase RasGAP_C PF03836.15 KFM73525.1 - 0.08 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 RasGAP C-terminus dNK PF01712.19 KFM73526.1 - 3.7e-41 141.3 0.4 5.1e-41 140.8 0.4 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 KFM73526.1 - 9.4e-08 32.0 0.1 4.1e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 KFM73526.1 - 2.6e-07 31.3 0.4 2.5e-06 28.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KFM73526.1 - 1.5e-06 28.4 0.0 3.7e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KFM73526.1 - 8.9e-06 25.9 0.3 0.05 13.7 0.2 2.7 3 0 0 3 3 3 2 Shikimate kinase TsaE PF02367.17 KFM73526.1 - 0.0026 17.7 0.2 0.0096 15.9 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 KFM73526.1 - 0.0062 16.3 0.0 0.038 13.7 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 KFM73526.1 - 0.0063 16.9 0.0 0.56 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain 8TM_micro PF17028.5 KFM73526.1 - 0.025 14.3 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain Ploopntkinase1 PF18748.1 KFM73526.1 - 0.044 13.3 0.0 0.48 9.9 0.0 2.5 3 0 0 3 3 3 0 P-loop Nucleotide Kinase1 AAA_22 PF13401.6 KFM73526.1 - 0.072 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM73526.1 - 0.19 11.5 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ANAPC4_WD40 PF12894.7 KFM73529.1 - 0.0083 16.4 0.1 0.068 13.5 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM73530.1 - 6.3e-10 39.5 4.6 0.0021 18.8 0.2 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM73530.1 - 2.3e-05 24.6 0.1 0.033 14.5 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM73530.1 - 0.028 13.4 0.2 0.052 12.5 0.0 1.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Orbi_VP4 PF05059.12 KFM73530.1 - 0.22 9.5 0.0 0.24 9.4 0.0 1.0 1 0 0 1 1 1 0 Orbivirus VP4 core protein Insulin PF00049.18 KFM73531.1 - 2.1e-05 25.4 3.3 0.017 16.1 0.8 2.2 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFM73531.1 - 0.0079 16.2 2.0 0.0079 16.2 2.0 2.5 2 1 0 2 2 2 1 Nematode insulin-related peptide beta type Insulin PF00049.18 KFM73533.1 - 1.2e-14 55.1 0.4 1.8e-14 54.5 0.4 1.3 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFM73533.1 - 0.00036 20.5 4.3 0.073 13.1 0.1 2.3 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type Insulin PF00049.18 KFM73534.1 - 1.4e-11 45.3 0.7 2.7e-11 44.3 0.7 1.5 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFM73534.1 - 0.00011 22.2 2.8 0.091 12.8 0.0 2.2 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type Guanylate_cyc PF00211.20 KFM73535.1 - 3.4e-25 88.7 0.0 4.9e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFM73536.1 - 1e-11 44.7 5.1 1.6e-11 44.0 5.1 1.2 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region Guanylate_cyc PF00211.20 KFM73536.1 - 3e-05 23.7 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HTH_23 PF13384.6 KFM73537.1 - 0.0084 15.9 0.2 0.01 15.6 0.2 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73537.1 - 0.021 15.4 0.6 0.11 13.1 0.7 1.8 1 1 1 2 2 2 0 Homeodomain-like domain HTH_IclR PF09339.10 KFM73537.1 - 0.12 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain DDE_3 PF13358.6 KFM73538.1 - 1.7e-10 40.8 0.0 2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM73539.1 - 2.9e-10 40.2 0.1 1e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM73539.1 - 0.0024 17.4 0.9 0.0024 17.4 0.9 2.3 2 1 0 2 2 2 1 Zinc-finger C2H2-type Cytochrom_B561 PF03188.16 KFM73540.1 - 0.0016 18.6 9.0 0.006 16.7 6.7 2.0 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 MARVEL PF01284.23 KFM73540.1 - 0.024 14.7 12.4 0.076 13.0 12.4 1.8 1 1 0 1 1 1 0 Membrane-associating domain SLATT_fungal PF18142.1 KFM73540.1 - 0.33 10.9 3.4 0.3 11.1 1.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain ETRAMP PF09716.10 KFM73542.1 - 0.09 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RT_RNaseH_2 PF17919.1 KFM73543.1 - 6.1e-31 106.4 0.0 1.7e-30 105.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM73543.1 - 3.7e-28 98.6 1.2 7.5e-28 97.6 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM73543.1 - 4.9e-28 97.5 0.0 1.5e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM73543.1 - 7.8e-20 70.7 0.2 2.9e-19 68.9 0.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM73543.1 - 6.5e-18 65.0 0.0 1.7e-15 57.2 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KFM73543.1 - 2.9e-09 37.4 0.0 9.2e-09 35.7 0.0 1.9 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM73543.1 - 1.5e-05 25.6 0.0 3.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM73543.1 - 1.7e-05 25.0 0.0 4.9e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KFM73543.1 - 5.2e-05 23.4 1.0 0.00013 22.1 1.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KFM73543.1 - 8.3e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Arc_C PF18162.1 KFM73543.1 - 0.00017 21.4 3.1 0.00018 21.3 0.6 2.3 2 0 0 2 2 2 1 Arc C-lobe RVT_3 PF13456.6 KFM73543.1 - 0.0026 17.5 0.1 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Asp_protease PF09668.10 KFM73543.1 - 0.0033 17.2 0.1 0.0074 16.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease BH4 PF02180.17 KFM73543.1 - 0.06 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 KRTAP PF11759.8 KFM73545.1 - 0.013 16.0 77.5 19 5.9 29.0 3.2 1 1 1 2 2 2 0 Keratin-associated matrix HTH_Tnp_Tc3_2 PF01498.18 KFM73548.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73548.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73548.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73548.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73548.1 - 2.1 9.0 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73549.1 - 8.1e-11 42.0 1.2 1.7e-10 41.0 1.2 1.5 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 KFM73549.1 - 2.7e-07 30.2 0.0 6.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73549.1 - 4.7e-05 23.1 0.8 0.00032 20.4 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KFM73549.1 - 0.0077 15.7 0.1 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_50 PF18024.1 KFM73549.1 - 0.0078 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KFM73549.1 - 0.022 14.4 0.4 0.075 12.7 0.0 2.0 3 0 0 3 3 3 0 Sigma-70, region 4 Slx4 PF09494.10 KFM73549.1 - 0.098 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Slx4 endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73550.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73550.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73550.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73550.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73550.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain BTB PF00651.31 KFM73551.1 - 1.5e-23 83.2 0.0 5.1e-22 78.2 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM73551.1 - 2.8e-10 40.2 0.1 6.5e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF5102 PF17104.5 KFM73551.1 - 3.8 7.5 8.4 0.62 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) HTH_Tnp_Tc3_2 PF01498.18 KFM73552.1 - 2.7e-16 59.6 2.2 4.9e-16 58.7 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73552.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ldl_recept_a PF00057.18 KFM73553.1 - 2.4e-10 40.4 6.7 3e-10 40.2 6.7 1.1 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFM73554.1 - 6e-08 33.0 0.0 0.00016 22.0 0.0 2.4 1 1 1 2 2 2 2 CUB domain CUB PF00431.20 KFM73555.1 - 0.015 15.7 0.0 1.6 9.1 0.0 3.0 2 1 0 3 3 3 0 CUB domain Pkinase_Tyr PF07714.17 KFM73556.1 - 1.5e-92 309.5 0.0 2.6e-92 308.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Focal_AT PF03623.13 KFM73556.1 - 3.9e-52 175.8 1.2 3.9e-52 175.8 1.2 2.1 2 0 0 2 2 2 1 Focal adhesion targeting region Pkinase PF00069.25 KFM73556.1 - 1.4e-47 162.3 0.0 5e-47 160.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain FERM_M PF00373.18 KFM73556.1 - 5.3e-13 49.4 0.1 2e-12 47.5 0.1 2.0 1 0 0 1 1 1 1 FERM central domain FERM_N_2 PF18038.1 KFM73556.1 - 9.8e-10 39.1 2.2 3.3e-09 37.5 1.3 2.4 2 0 0 2 2 2 1 FERM N-terminal domain Haspin_kinase PF12330.8 KFM73556.1 - 0.0002 20.4 0.2 0.00051 19.1 0.2 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM73556.1 - 0.0068 15.7 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DUF1759 PF03564.15 KFM73558.1 - 1.2e-06 28.5 0.0 1.4e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) NTF2 PF02136.20 KFM73559.1 - 7e-18 65.3 0.3 7.7e-18 65.2 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain NTF2 PF02136.20 KFM73560.1 - 0.0011 19.5 0.1 0.0013 19.3 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Pkinase PF00069.25 KFM73562.1 - 1.7e-53 181.7 0.0 1.9e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73562.1 - 3.8e-24 85.4 0.0 4.4e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM73562.1 - 2e-06 27.3 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM73562.1 - 4.9e-06 25.7 0.1 6.5e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM73562.1 - 0.00058 19.3 0.0 0.00081 18.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM73562.1 - 0.0012 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFM73562.1 - 0.0098 15.5 0.2 0.018 14.6 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFM73562.1 - 0.012 14.5 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KFM73562.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YukC PF10140.9 KFM73562.1 - 0.16 10.7 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Alpha-amylase_C PF02806.18 KFM73565.1 - 4e-27 94.5 0.1 7.6e-27 93.6 0.1 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain HTH_Tnp_Tc3_2 PF01498.18 KFM73566.1 - 2.1e-16 59.9 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73566.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73567.1 - 4.8e-16 58.8 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73567.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73567.1 - 1.9e-07 30.7 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73567.1 - 0.0027 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73567.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_1 PF03184.19 KFM73568.1 - 3.8e-50 169.9 0.1 7e-50 169.1 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM73568.1 - 2e-12 47.0 0.0 1.6e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM73568.1 - 0.00073 19.1 0.0 0.0032 17.1 0.0 2.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain 7tm_1 PF00001.21 KFM73569.1 - 7.9e-45 153.2 7.6 1.1e-44 152.8 7.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM73569.1 - 1.7e-05 24.3 14.4 3e-05 23.6 14.4 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM73569.1 - 0.00023 20.9 18.1 0.0005 19.8 18.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFM73569.1 - 0.0055 16.5 11.6 0.0079 16.0 11.4 1.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 KFM73569.1 - 0.12 11.7 12.0 0.17 11.1 12.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw SpmSyn_N PF17950.1 KFM73570.1 - 0.082 13.1 0.3 0.21 11.8 0.1 1.8 1 1 1 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal DUF2757 PF10955.8 KFM73570.1 - 0.12 12.7 1.8 0.21 11.9 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) Lig_chan PF00060.26 KFM73571.1 - 1.9e-25 89.5 0.0 2.7e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 KFM73571.1 - 2.2e-09 37.1 0.0 3.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Microcin PF03526.13 KFM73571.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein OppC_N PF12911.7 KFM73571.1 - 0.12 12.3 5.1 0.67 10.0 0.0 3.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C ANF_receptor PF01094.28 KFM73572.1 - 3.9e-20 72.3 0.1 3.2e-18 66.0 0.1 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFM73572.1 - 2.2e-07 31.1 0.2 1.1e-06 28.8 0.0 2.2 2 1 1 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site Antifungal_pept PF11410.8 KFM73572.1 - 3.8 7.5 6.0 1.3 8.9 1.1 2.4 3 0 0 3 3 3 0 Antifungal peptide Str_synth PF03088.16 KFM73574.1 - 5.4e-23 80.9 0.3 3.4e-22 78.4 0.0 2.3 3 0 0 3 3 3 1 Strictosidine synthase SGL PF08450.12 KFM73574.1 - 8e-13 48.5 0.0 2.6e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region MORN_2 PF07661.13 KFM73574.1 - 0.014 15.6 0.0 0.1 12.9 0.0 2.6 1 1 0 1 1 1 0 MORN repeat variant Mic1 PF07035.12 KFM73575.1 - 2.4e-59 199.6 4.7 2.4e-59 199.6 4.7 1.8 1 1 1 2 2 2 1 Colon cancer-associated protein Mic1-like Fanconi_A_N PF15865.5 KFM73575.1 - 0.00081 18.9 3.4 0.0016 17.9 3.4 1.5 1 0 0 1 1 1 1 Fanconi anaemia group A protein N terminus Imm6 PF14434.6 KFM73576.1 - 0.0079 16.1 0.0 0.0088 16.0 0.0 1.1 1 0 0 1 1 1 1 Immunity protein Imm6 Acyl-CoA_dh_1 PF00441.24 KFM73577.1 - 0.11 12.7 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Spuma_A9PTase PF03539.14 KFM73578.1 - 0.017 15.2 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) DUF4665 PF15679.5 KFM73578.1 - 0.066 13.8 0.0 0.099 13.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4665) ATP-synt PF00231.19 KFM73578.1 - 0.079 12.7 0.0 0.093 12.4 0.0 1.0 1 0 0 1 1 1 0 ATP synthase CBM_14 PF01607.24 KFM73579.1 - 2e-10 40.7 4.6 6.7e-10 39.0 4.6 2.0 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Tetraspanin PF00335.20 KFM73580.1 - 1.9e-29 103.0 5.8 2.1e-29 102.9 5.8 1.0 1 0 0 1 1 1 1 Tetraspanin family PsaM PF07465.13 KFM73580.1 - 0.13 12.0 1.9 0.26 11.0 1.9 1.5 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) SUR7 PF06687.12 KFM73580.1 - 6.9 6.2 10.1 0.46 10.1 4.9 1.6 1 1 1 2 2 2 0 SUR7/PalI family SPT2 PF08243.11 KFM73581.1 - 1.5e-18 67.3 14.7 1.5e-18 67.3 14.7 4.0 3 1 2 5 5 5 1 SPT2 chromatin protein zf-CCHC PF00098.23 KFM73582.1 - 1.6e-06 27.9 2.5 2.5e-06 27.3 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM73582.1 - 0.037 13.7 0.6 0.064 13.0 0.6 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM73582.1 - 0.058 13.1 0.8 0.094 12.5 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle DDE_3 PF13358.6 KFM73583.1 - 5.1e-14 52.3 0.0 8.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73583.1 - 1.4e-10 41.3 1.0 2.1e-10 40.7 1.0 1.3 1 0 0 1 1 1 1 Transposase XRCC4 PF06632.12 KFM73584.1 - 3e-22 79.0 16.3 3.8e-22 78.6 16.3 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 ALMT PF11744.8 KFM73584.1 - 1.5 7.6 10.7 2.1 7.1 10.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TGF_beta PF00019.20 KFM73585.1 - 1.1e-25 90.6 9.0 2.6e-25 89.4 3.2 3.0 4 0 0 4 4 4 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFM73585.1 - 1.9e-13 50.8 0.0 2.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide GW PF13457.6 KFM73585.1 - 0.1 13.2 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 GW (Gly-Tryp) dipeptide domain CN_hydrolase PF00795.22 KFM73586.1 - 1.6e-11 44.1 0.0 2.4e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LRR_8 PF13855.6 KFM73587.1 - 2.4e-16 59.2 8.7 2.9e-10 39.7 0.7 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM73587.1 - 6.8e-10 39.1 11.2 7.1e-06 26.3 4.8 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM73587.1 - 2.9e-06 27.0 9.3 0.42 11.3 0.8 4.5 3 1 1 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 KFM73587.1 - 0.00014 21.6 10.0 0.22 11.7 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 KFM73587.1 - 0.0022 17.5 1.4 0.034 13.6 1.2 2.0 1 1 1 2 2 2 1 Leucine-rich repeat COesterase PF00135.28 KFM73588.1 - 2.1e-45 155.6 0.0 2.3e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family CBM_14 PF01607.24 KFM73589.1 - 6.4e-32 109.5 28.3 6e-11 42.3 4.2 3.3 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Baculo_VP91_N PF08475.10 KFM73589.1 - 5.9 6.5 19.5 0.39 10.4 1.7 3.9 2 2 1 3 3 3 0 Viral capsid protein 91 N-terminal CBM_14 PF01607.24 KFM73590.1 - 4.7e-42 141.9 54.1 1.2e-09 38.2 3.9 6.2 6 0 0 6 6 6 6 Chitin binding Peritrophin-A domain Brr6_like_C_C PF10104.9 KFM73590.1 - 1.6 8.5 12.8 2.8 7.7 0.7 4.3 3 1 1 4 4 4 0 Di-sulfide bridge nucleocytoplasmic transport domain Baculo_VP91_N PF08475.10 KFM73590.1 - 8.8 6.0 10.4 0.16 11.7 1.8 2.4 3 0 0 3 3 3 0 Viral capsid protein 91 N-terminal 2OG-FeII_Oxy_2 PF13532.6 KFM73591.1 - 1.7e-16 61.0 0.0 4.2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RE_NgoBV PF09564.10 KFM73591.1 - 0.014 14.8 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 NgoBV restriction endonuclease DDE_3 PF13358.6 KFM73592.1 - 4.3e-20 72.0 0.0 1.3e-12 47.7 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73592.1 - 3.8e-16 59.1 2.2 7.8e-16 58.1 2.2 1.6 1 0 0 1 1 1 1 Transposase TRAP-gamma PF07074.12 KFM73593.1 - 8.2e-86 285.8 6.7 9.4e-86 285.6 6.7 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Renin_r PF07850.14 KFM73593.1 - 0.034 14.8 0.8 0.66 10.6 0.3 2.2 2 0 0 2 2 2 0 Renin receptor-like protein YoaP PF14268.6 KFM73593.1 - 1 8.9 3.4 3.4 7.3 0.9 2.3 2 0 0 2 2 2 0 YoaP-like DUF4203 PF13886.6 KFM73594.1 - 1.5e-40 139.1 39.7 1.7e-40 138.8 39.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF983 PF06170.12 KFM73594.1 - 1.3 9.4 13.8 4.6 7.7 5.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF983) NDUF_B12 PF08122.12 KFM73594.1 - 2 8.5 4.8 16 5.6 0.2 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Mito_carr PF00153.27 KFM73595.1 - 9.4e-66 217.8 6.7 2.9e-23 81.6 0.1 3.6 2 2 1 3 3 3 3 Mitochondrial carrier protein ECF_trnsprt PF12822.7 KFM73595.1 - 0.024 14.7 2.1 0.19 11.8 1.1 2.4 1 1 0 1 1 1 0 ECF transporter, substrate-specific component CbiM PF01891.16 KFM73595.1 - 0.031 14.1 3.5 0.68 9.7 0.5 2.5 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region DNA_III_psi PF03603.13 KFM73595.1 - 0.051 13.8 0.1 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III psi subunit FAIM1 PF06905.13 KFM73596.1 - 3.5e-69 232.0 2.8 3.9e-69 231.8 2.8 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) PCC_BT PF18140.1 KFM73596.1 - 0.23 11.8 4.0 2.2 8.6 0.4 2.2 1 1 1 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain Asp_protease_2 PF13650.6 KFM73598.1 - 0.0059 17.2 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM73598.1 - 0.0063 17.0 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DDE_Tnp_1_7 PF13843.6 KFM73599.1 - 1.9e-46 159.0 1.4 2.5e-46 158.6 1.4 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM73599.1 - 4.2e-08 33.9 9.4 1.2e-07 32.4 9.4 1.8 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon DDE_Tnp_1 PF01609.21 KFM73599.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain PIP5K PF01504.18 KFM73599.1 - 0.024 13.8 0.2 0.043 13.0 0.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase C1_2 PF03107.16 KFM73599.1 - 0.027 14.8 3.5 0.074 13.4 3.5 1.8 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.24 KFM73599.1 - 0.24 11.6 5.7 0.6 10.3 5.7 1.7 1 0 0 1 1 1 0 B-box zinc finger zf-HIT PF04438.16 KFM73599.1 - 0.37 10.7 6.7 0.73 9.8 6.7 1.5 1 0 0 1 1 1 0 HIT zinc finger I-set PF07679.16 KFM73600.1 - 3e-50 168.2 0.0 7.3e-18 64.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM73600.1 - 2.4e-47 159.4 0.0 6.9e-15 55.4 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM73600.1 - 4.8e-32 110.1 0.1 2.3e-10 40.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM73600.1 - 7.9e-30 102.9 0.6 2.6e-12 46.7 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain LRR_8 PF13855.6 KFM73600.1 - 4e-26 90.5 5.8 3.8e-13 49.0 0.2 2.6 2 0 0 2 2 2 2 Leucine rich repeat V-set PF07686.17 KFM73600.1 - 1e-17 64.2 3.9 2.5e-07 30.8 0.1 5.6 3 2 0 3 3 3 3 Immunoglobulin V-set domain LRR_5 PF13306.6 KFM73600.1 - 1.2e-12 47.9 0.3 4e-12 46.2 0.3 1.8 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM73600.1 - 2.4e-12 46.8 5.7 9.4e-06 25.9 0.1 4.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) C2-set_2 PF08205.12 KFM73600.1 - 1.6e-11 44.1 0.0 0.0002 21.3 0.0 3.5 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM73600.1 - 1.8e-07 31.5 0.3 0.062 13.7 0.0 4.2 3 2 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM73600.1 - 2.9e-06 26.7 0.1 2.8 7.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain C1-set PF07654.15 KFM73600.1 - 1e-05 25.8 0.1 0.002 18.4 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin C1-set domain LRR_9 PF14580.6 KFM73600.1 - 1.9e-05 24.3 1.8 0.053 13.0 0.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Izumo-Ig PF16706.5 KFM73600.1 - 2.7e-05 24.1 0.5 3.9 7.6 0.0 4.2 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFM73600.1 - 0.00034 20.8 0.1 0.33 11.2 0.0 3.6 3 1 1 4 4 4 1 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 KFM73600.1 - 0.00054 19.9 0.0 6.4 6.9 0.0 3.6 3 0 0 3 3 3 2 C17orf99 Ig domain LRR_1 PF00560.33 KFM73600.1 - 0.016 15.7 0.4 83 4.4 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat LRRCT PF01463.24 KFM73600.1 - 0.042 14.4 0.1 0.18 12.4 0.1 2.2 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain DOT1 PF08123.13 KFM73600.1 - 0.054 13.0 0.2 0.77 9.3 0.0 2.3 1 1 1 2 2 2 0 Histone methylation protein DOT1 LRR_6 PF13516.6 KFM73600.1 - 0.062 13.4 8.3 1.3 9.2 0.3 4.6 4 0 0 4 4 4 0 Leucine Rich repeat C2-set PF05790.15 KFM73600.1 - 0.084 13.1 0.1 17 5.7 0.0 4.0 5 0 0 5 5 4 0 Immunoglobulin C2-set domain DUF2749 PF10907.8 KFM73600.1 - 0.093 12.9 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) HTH_Tnp_Tc3_2 PF01498.18 KFM73601.1 - 1.9e-17 63.3 1.4 3.9e-17 62.2 1.4 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73601.1 - 2.6e-14 53.2 0.0 4.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM73601.1 - 4.4e-06 27.2 9.9 5.4e-06 26.9 2.3 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_3 PF01381.22 KFM73601.1 - 0.001 19.1 0.7 0.032 14.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix MarR_2 PF12802.7 KFM73601.1 - 0.001 18.9 0.5 0.067 13.1 0.0 2.5 2 0 0 2 2 2 1 MarR family PAX PF00292.18 KFM73601.1 - 0.006 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.6 KFM73601.1 - 0.011 15.8 2.1 0.17 12.0 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM73601.1 - 0.011 15.5 1.5 0.25 11.2 0.1 2.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM73601.1 - 0.012 15.6 1.5 0.048 13.6 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM73601.1 - 0.063 12.8 1.6 0.86 9.2 0.0 2.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF5345 PF17280.2 KFM73602.1 - 0.33 10.9 1.0 0.71 9.9 1.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) MITF_TFEB_C_3_N PF15951.5 KFM73603.1 - 4.6e-25 89.0 8.0 4.6e-25 89.0 8.0 2.3 2 0 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus HLH PF00010.26 KFM73603.1 - 4.5e-13 48.9 0.9 1.1e-12 47.7 0.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Striatin PF08232.12 KFM73603.1 - 0.0088 16.6 8.5 0.18 12.4 0.3 2.7 3 0 0 3 3 3 2 Striatin family Sigma70_r3 PF04539.16 KFM73603.1 - 0.024 14.7 0.1 0.21 11.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-70 region 3 MHC_I_2 PF14586.6 KFM73603.1 - 0.056 13.3 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 HTH_Tnp_Tc3_2 PF01498.18 KFM73604.1 - 4.1e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73604.1 - 1.7e-14 53.8 0.0 3.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73604.1 - 2.5e-07 30.3 1.6 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73604.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73604.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DHFR_1 PF00186.19 KFM73605.1 - 4.4e-39 133.8 0.0 5.3e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Phage_term_smal PF05944.12 KFM73605.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage small terminase subunit Josephin PF02099.17 KFM73605.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Josephin HTH_Tnp_Tc3_2 PF01498.18 KFM73606.1 - 2.4e-16 59.7 2.2 6.4e-16 58.4 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73606.1 - 1.6e-13 50.7 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73606.1 - 3.3e-07 29.9 1.6 7.8e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73606.1 - 0.0032 17.2 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73606.1 - 3.2 8.4 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_IS1595 PF12762.7 KFM73607.1 - 2.5e-06 27.6 0.7 3.2e-06 27.2 0.7 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain PAP_PilO PF06864.12 KFM73607.1 - 0.047 12.5 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) zf-H2C2_2 PF13465.6 KFM73608.1 - 5e-15 55.2 14.3 1.1e-07 31.9 2.4 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73608.1 - 1.3e-10 41.1 13.5 5e-05 23.5 2.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 KFM73608.1 - 6.7e-09 35.8 11.8 0.00016 22.0 2.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM73608.1 - 1.7e-07 31.5 15.5 0.0008 20.0 2.9 2.7 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM73608.1 - 0.00059 19.5 11.4 0.053 13.3 1.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM73608.1 - 0.00085 19.3 17.8 0.06 13.4 4.6 3.9 2 2 0 2 2 2 1 C2H2-type zinc finger TRAF6_Z2 PF18048.1 KFM73608.1 - 0.0016 18.5 3.3 1.1 9.4 0.1 2.5 2 1 0 2 2 2 2 TNF receptor-associated factor 6 zinc finger 2 DUF2256 PF10013.9 KFM73608.1 - 0.0025 17.9 1.1 1.7 8.8 0.1 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) C5HCH PF17982.1 KFM73608.1 - 0.0031 17.6 3.8 0.64 10.2 0.3 2.1 1 1 1 2 2 2 2 NSD Cys-His rich domain zf-C2H2_jaz PF12171.8 KFM73608.1 - 0.0032 17.7 11.1 0.13 12.6 2.4 2.8 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-SNAP50_C PF12251.8 KFM73608.1 - 0.0034 17.1 2.7 0.0037 17.0 2.7 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C2HC_2 PF13913.6 KFM73608.1 - 0.0079 16.1 0.5 4.1 7.4 0.1 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-HIT PF04438.16 KFM73608.1 - 0.01 15.7 4.9 1.2 9.1 0.5 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-Di19 PF05605.12 KFM73608.1 - 0.014 15.7 8.8 0.05 13.9 1.0 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding YyzF PF14116.6 KFM73608.1 - 0.018 15.1 1.1 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 YyzF-like protein DZR PF12773.7 KFM73608.1 - 0.038 14.0 0.3 0.056 13.5 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon BHD_1 PF10403.9 KFM73608.1 - 0.051 13.4 0.5 3.2 7.7 0.1 2.2 1 1 1 2 2 2 0 Rad4 beta-hairpin domain 1 Nore1-SARAH PF16517.5 KFM73608.1 - 0.081 12.8 0.0 9.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain zf-C2H2_2 PF12756.7 KFM73608.1 - 0.15 12.4 10.4 1.7 9.0 2.1 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KFM73608.1 - 0.17 12.0 11.5 0.27 11.3 4.7 2.3 1 1 1 2 2 2 0 BED zinc finger Laminin_N PF00055.17 KFM73608.1 - 0.2 11.2 2.7 6 6.4 0.3 2.0 1 1 1 2 2 2 0 Laminin N-terminal (Domain VI) zf_UBZ PF18439.1 KFM73608.1 - 0.28 10.8 3.5 5.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 KFM73608.1 - 0.44 10.7 5.8 1.1 9.5 5.8 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-MYST PF17772.1 KFM73608.1 - 1.2 8.8 8.3 1.6 8.4 0.5 2.6 3 0 0 3 3 3 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 KFM73609.1 - 9.5e-75 244.0 75.7 2.5e-09 37.1 1.0 11.0 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73609.1 - 2.6e-52 172.4 89.3 1.3e-06 28.5 0.8 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73609.1 - 3.9e-40 133.0 84.2 0.00016 22.3 0.8 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM73609.1 - 3e-27 94.1 74.2 0.00061 20.1 0.7 10.3 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM73609.1 - 3.3e-19 68.7 59.8 0.017 15.4 0.3 10.5 9 1 1 10 10 10 10 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM73609.1 - 1.5e-15 56.6 61.4 0.096 12.5 0.1 10.6 10 0 0 10 10 10 10 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM73609.1 - 3.2e-07 30.3 36.4 1.2 9.2 0.5 9.3 10 0 0 10 10 10 4 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM73609.1 - 9.7e-06 25.5 28.9 0.88 9.6 1.4 6.9 5 2 2 7 7 7 4 Adenylate kinase, active site lid zf-C2H2_6 PF13912.6 KFM73609.1 - 2.5e-05 24.2 79.7 0.062 13.3 0.8 12.1 12 0 0 12 12 12 5 C2H2-type zinc finger BolA PF01722.18 KFM73609.1 - 0.00011 22.4 13.7 1.9 8.8 0.7 5.8 1 1 2 5 5 5 2 BolA-like protein GAGA PF09237.11 KFM73609.1 - 0.00029 20.6 14.8 1.1 9.1 0.1 6.5 3 2 4 7 7 7 2 GAGA factor Tox-HNH-HHH PF15637.6 KFM73609.1 - 0.0035 17.5 2.3 2.7 8.2 0.0 4.6 1 1 5 6 6 6 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF2256 PF10013.9 KFM73609.1 - 0.0036 17.4 35.2 4.3 7.5 0.3 9.7 10 0 0 10 10 10 1 Uncharacterized protein conserved in bacteria (DUF2256) BHD_1 PF10403.9 KFM73609.1 - 0.0078 16.0 2.8 19 5.2 0.0 5.0 4 2 1 5 5 5 0 Rad4 beta-hairpin domain 1 YyzF PF14116.6 KFM73609.1 - 0.0084 16.1 31.8 4.5 7.4 0.2 9.3 10 0 0 10 10 10 1 YyzF-like protein FYDLN_acid PF09538.10 KFM73609.1 - 0.0098 16.6 16.4 21 5.8 0.3 6.6 3 1 2 5 5 5 0 Protein of unknown function (FYDLN_acid) PqqA PF08042.11 KFM73609.1 - 0.012 15.6 0.5 2.2e+02 2.1 0.0 5.2 5 0 0 5 5 5 0 PqqA family zf-C2H2_2 PF12756.7 KFM73609.1 - 0.026 14.9 65.2 2.6 8.4 0.4 9.7 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) TRAF6_Z2 PF18048.1 KFM73609.1 - 0.029 14.5 0.1 0.029 14.5 0.1 9.9 10 0 0 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 GATase_2 PF00310.21 KFM73609.1 - 0.041 12.6 0.1 5 5.7 0.0 2.6 1 1 1 3 3 3 0 Glutamine amidotransferases class-II FAM83 PF07894.12 KFM73609.1 - 0.069 12.7 1.8 2.4 7.7 0.2 2.4 2 1 0 2 2 2 0 FAM83 A-H zf-MYST PF17772.1 KFM73609.1 - 0.15 11.7 46.5 3.6 7.3 0.1 9.7 4 2 6 10 10 10 0 MYST family zinc finger domain zf_UBZ PF18439.1 KFM73609.1 - 0.16 11.6 43.9 8.8 6.0 0.1 10.0 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM73609.1 - 0.67 10.1 36.5 0.91 9.7 4.8 4.5 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFM73609.1 - 1.5 9.6 37.4 3.8 8.3 2.5 5.4 1 1 6 7 7 7 0 zinc-ribbon family TerY_C PF15616.6 KFM73609.1 - 3 8.0 23.3 2.4 8.3 0.9 5.0 1 1 5 6 6 6 0 TerY-C metal binding domain zf-CHCC PF10276.9 KFM73609.1 - 6.2 7.0 20.0 66 3.7 0.0 8.0 10 0 0 10 10 10 0 Zinc-finger domain zf-H2C2_2 PF13465.6 KFM73610.1 - 2.2e-84 274.4 77.7 5.6e-09 36.0 0.9 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73610.1 - 6.1e-62 202.8 87.6 1.2e-06 28.7 0.5 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73610.1 - 7.6e-43 141.5 83.7 0.00076 20.1 1.3 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM73610.1 - 1.3e-32 111.2 80.2 0.0022 18.3 0.9 11.3 11 0 0 11 11 11 11 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM73610.1 - 2.8e-18 65.4 59.0 0.0026 17.5 0.1 11.3 11 0 0 11 11 11 6 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM73610.1 - 2.5e-17 62.7 65.4 0.051 13.9 0.5 11.5 11 0 0 11 11 11 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM73610.1 - 2.5e-16 59.2 80.5 0.047 13.7 0.8 12.0 11 1 0 11 11 11 10 C2H2-type zinc finger BolA PF01722.18 KFM73610.1 - 4e-09 36.6 14.6 0.0075 16.5 0.5 6.1 2 1 4 6 6 6 2 BolA-like protein ADK_lid PF05191.14 KFM73610.1 - 2.4e-08 33.8 34.6 0.0063 16.5 2.2 6.7 4 2 3 7 7 7 5 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM73610.1 - 1.2e-07 31.4 34.1 2.6 8.1 0.1 11.1 11 0 0 11 11 11 2 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFM73610.1 - 6.1e-07 29.1 57.8 0.093 12.5 1.0 10.3 11 0 0 11 11 11 6 zinc-finger C2H2-type GAGA PF09237.11 KFM73610.1 - 1.6e-06 27.8 13.5 1.2 9.0 0.4 7.4 2 1 5 8 8 8 2 GAGA factor C5HCH PF17982.1 KFM73610.1 - 9.5e-05 22.5 48.8 13 6.1 0.2 10.9 5 2 6 11 11 11 0 NSD Cys-His rich domain zf-Sec23_Sec24 PF04810.15 KFM73610.1 - 0.00013 22.0 36.0 0.46 10.6 0.0 9.8 9 2 2 11 11 11 3 Sec23/Sec24 zinc finger FYVE PF01363.21 KFM73610.1 - 0.00024 21.2 51.9 0.45 10.7 6.2 6.0 1 1 4 5 5 5 2 FYVE zinc finger DUF2256 PF10013.9 KFM73610.1 - 0.00025 21.1 33.9 15 5.8 0.1 10.7 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) Tox-HNH-HHH PF15637.6 KFM73610.1 - 0.00033 20.8 5.9 3.8 7.7 0.1 4.6 1 1 4 5 5 5 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_9 PF16293.5 KFM73610.1 - 0.0011 18.8 43.0 3.4 7.6 0.1 10.4 2 2 9 11 11 11 1 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM73610.1 - 0.0034 17.5 41.5 0.24 11.5 11.3 4.7 1 1 2 4 4 4 2 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM73610.1 - 0.0059 16.7 46.2 9.2 6.5 1.0 10.9 11 0 0 11 11 11 0 DBF zinc finger C1_1 PF00130.22 KFM73610.1 - 0.0061 16.4 59.5 0.56 10.1 7.6 9.6 2 2 8 10 10 10 2 Phorbol esters/diacylglycerol binding domain (C1 domain) TRAF6_Z2 PF18048.1 KFM73610.1 - 0.011 15.8 54.7 0.44 10.7 1.8 10.9 11 0 0 11 11 11 0 TNF receptor-associated factor 6 zinc finger 2 zf-Dof PF02701.15 KFM73610.1 - 0.091 12.9 25.0 11 6.2 0.2 8.7 2 2 6 8 8 8 0 Dof domain, zinc finger zinc_ribbon_15 PF17032.5 KFM73610.1 - 0.12 13.2 44.3 2 9.2 2.2 5.9 1 1 4 6 6 6 0 zinc-ribbon family zf-MYST PF17772.1 KFM73610.1 - 0.12 12.0 46.9 1.2 8.8 0.5 10.4 6 4 5 11 11 11 0 MYST family zinc finger domain Mga PF05043.13 KFM73610.1 - 0.19 12.3 4.1 24 5.6 0.0 4.1 5 0 0 5 5 4 0 Mga helix-turn-helix domain zf-CHCC PF10276.9 KFM73610.1 - 0.52 10.4 18.6 47 4.1 0.0 8.7 11 0 0 11 11 11 0 Zinc-finger domain zf-C2H2_2 PF12756.7 KFM73610.1 - 0.55 10.6 76.3 2.1 8.7 3.0 10.4 1 1 9 10 10 10 0 C2H2 type zinc-finger (2 copies) Scramblase PF03803.15 KFM73610.1 - 1.4 8.2 9.4 1 8.6 0.7 2.9 1 1 3 4 4 4 0 Scramblase DUF4764 PF15961.5 KFM73610.1 - 1.5 7.4 38.6 4.1 6.0 0.1 7.8 2 2 6 8 8 8 0 Domain of unknown function (DUF4764) PqqA PF08042.11 KFM73610.1 - 2.3 8.4 5.4 4.6e+02 1.1 0.0 5.5 7 0 0 7 7 7 0 PqqA family zf-H2C2_2 PF13465.6 KFM73612.1 - 4.8e-76 248.1 84.9 1.5e-08 34.7 0.6 12.1 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73612.1 - 2e-49 163.3 107.1 7.7e-05 22.9 4.4 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73612.1 - 2e-35 118.4 102.7 0.00034 21.2 1.7 11.1 11 0 0 11 11 11 10 C2H2-type zinc finger zf-met PF12874.7 KFM73612.1 - 2.8e-25 87.9 93.3 0.0033 17.7 2.9 11.5 10 1 2 12 12 12 10 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM73612.1 - 5.4e-16 58.0 66.1 0.0098 15.6 0.6 11.4 11 0 0 11 11 11 9 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM73612.1 - 1.6e-15 56.6 98.3 0.00076 19.4 2.0 11.4 11 0 0 11 11 11 7 C2H2-type zinc finger BolA PF01722.18 KFM73612.1 - 7e-10 39.0 12.3 0.43 10.9 1.5 7.5 1 1 8 9 9 9 3 BolA-like protein GAGA PF09237.11 KFM73612.1 - 2.1e-07 30.6 19.8 0.16 11.8 0.3 7.2 2 2 6 8 8 8 3 GAGA factor zf-C2H2_jaz PF12171.8 KFM73612.1 - 2.9e-06 27.4 80.9 0.02 15.2 1.4 11.3 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM73612.1 - 2.6e-05 24.2 37.2 1.6 8.8 0.1 10.5 6 4 4 10 10 10 2 Sec23/Sec24 zinc finger Zf_RING PF16744.5 KFM73612.1 - 0.0031 17.6 63.2 2.1 8.5 0.4 10.7 2 2 6 8 8 8 2 KIAA1045 RING finger Tox-HNH-HHH PF15637.6 KFM73612.1 - 0.007 16.5 1.5 16 5.7 0.1 4.4 1 1 5 6 6 6 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Complex1_49kDa PF00346.19 KFM73612.1 - 0.23 10.6 0.4 8 5.5 0.1 2.6 1 1 3 4 4 4 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Closter_coat PF01785.17 KFM73612.1 - 0.73 9.1 5.1 0.92 8.7 0.3 2.8 3 1 0 4 4 4 0 Closterovirus coat protein zf-DBF PF07535.12 KFM73612.1 - 0.73 10.0 61.0 12 6.1 0.1 11.2 11 0 0 11 11 11 0 DBF zinc finger zf-C2H2_9 PF16293.5 KFM73612.1 - 1 9.3 52.7 8 6.4 0.3 10.5 2 2 9 11 11 11 0 C2H2 type zinc-finger (1 copy) zf-Paramyx-P PF13008.7 KFM73612.1 - 1.1 8.8 23.3 31 4.1 0.1 7.5 7 0 0 7 7 7 0 Zinc-binding domain of Paramyxoviridae V protein zf-C2H2_11 PF16622.5 KFM73612.1 - 1.1 9.1 67.6 0.48 10.2 0.3 10.5 11 0 0 11 11 11 0 zinc-finger C2H2-type C1_4 PF07975.12 KFM73612.1 - 2 8.7 63.3 6.3 7.1 4.7 7.8 2 1 6 8 8 8 0 TFIIH C1-like domain Viral_cys_rich PF08008.12 KFM73612.1 - 4.4 7.4 18.6 9.2 6.4 0.6 5.2 2 2 4 6 6 6 0 Viral cysteine rich DUF4371 PF14291.6 KFM73613.1 - 2.8e-07 30.4 0.0 5.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM73613.1 - 0.023 14.5 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region SH3_1 PF00018.28 KFM73615.1 - 3e-36 122.8 0.4 8.1e-17 60.6 0.0 3.3 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KFM73615.1 - 9.4e-32 108.6 0.0 6.4e-17 61.2 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH2 PF00017.24 KFM73615.1 - 1e-23 83.2 0.1 2.2e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_2 PF07653.17 KFM73615.1 - 2.5e-22 78.3 0.0 1.6e-11 43.7 0.0 3.1 2 1 2 4 4 4 2 Variant SH3 domain SH2_2 PF14633.6 KFM73615.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 KFM73615.1 - 0.0018 18.5 0.1 0.21 11.9 0.0 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain TUDOR PF00567.24 KFM73615.1 - 0.04 13.9 0.0 7 6.7 0.0 2.3 2 0 0 2 2 2 0 Tudor domain DUF5093 PF17011.5 KFM73615.1 - 0.049 13.9 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) SH3_10 PF17902.1 KFM73615.1 - 0.18 11.9 0.0 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 SH3 domain DUF5348 PF17295.2 KFM73615.1 - 0.31 11.0 3.0 22 5.1 1.4 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5348) Nop25 PF09805.9 KFM73616.1 - 1.8e-12 47.9 12.1 1.8e-12 47.9 12.1 2.3 1 1 1 2 2 1 1 Nucleolar protein 12 (25kDa) TSC22 PF01166.18 KFM73616.1 - 0.059 13.7 1.1 0.059 13.7 1.1 2.7 2 1 0 2 2 2 0 TSC-22/dip/bun family NPR2 PF06218.11 KFM73616.1 - 0.1 11.3 3.1 0.042 12.6 0.5 1.6 1 1 1 2 2 2 0 Nitrogen permease regulator 2 MnmE_helical PF12631.7 KFM73616.1 - 0.16 12.1 3.9 0.22 11.7 3.9 1.3 1 0 0 1 1 1 0 MnmE helical domain DUF4065 PF13274.6 KFM73616.1 - 0.17 12.8 6.1 0.27 12.1 5.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) DUF2990 PF11693.8 KFM73616.1 - 0.17 12.1 0.2 7.5 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Sld5 PF05916.11 KFM73616.1 - 0.18 12.3 4.7 0.47 10.9 4.6 1.8 1 1 0 1 1 1 0 GINS complex protein SNARE PF05739.19 KFM73616.1 - 0.33 11.0 6.4 0.13 12.3 2.3 2.3 2 0 0 2 2 2 0 SNARE domain DUF3492 PF11997.8 KFM73616.1 - 0.61 9.8 10.3 0.43 10.3 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) Sen15 PF09631.10 KFM73616.1 - 0.73 10.2 4.3 2.1 8.7 4.0 2.1 1 1 0 1 1 1 0 Sen15 protein NLRC4_HD2 PF17776.1 KFM73616.1 - 1.3 9.6 6.9 1.8 9.1 0.9 2.3 2 0 0 2 2 2 0 NLRC4 helical domain HD2 FeoB_Cyto PF17910.1 KFM73616.1 - 2.3 8.8 9.7 3 8.5 1.6 2.4 2 1 0 2 2 2 0 FeoB cytosolic helical domain DUF4358 PF14270.6 KFM73616.1 - 3.9 7.8 8.3 1.8 8.9 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) HTH_Tnp_Tc5 PF03221.16 KFM73617.1 - 2e-16 59.7 0.0 3.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM73617.1 - 3.2e-10 39.5 0.4 7.9e-10 38.2 0.4 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain FbpC_C_terminal PF17845.1 KFM73617.1 - 0.17 12.0 0.2 0.51 10.5 0.0 1.9 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain zf-C2H2 PF00096.26 KFM73618.1 - 5.6e-06 26.5 17.9 0.0011 19.3 1.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73618.1 - 0.00052 20.6 13.0 0.01 16.6 0.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM73618.1 - 0.015 15.6 10.7 0.43 11.0 4.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFM73618.1 - 0.016 15.6 10.5 0.17 12.4 3.4 3.0 3 0 0 3 3 3 0 Zinc-finger double domain BolA PF01722.18 KFM73618.1 - 0.053 13.8 0.5 0.094 13.0 0.5 1.3 1 0 0 1 1 1 0 BolA-like protein zf-CCHC_2 PF13696.6 KFM73618.1 - 0.21 11.5 19.0 1.1 9.1 1.2 3.3 2 1 0 2 2 2 0 Zinc knuckle zf-Sec23_Sec24 PF04810.15 KFM73618.1 - 1.2 9.3 11.1 0.47 10.5 0.6 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM73618.1 - 2.8 7.6 8.5 0.77 9.4 0.5 2.3 1 1 1 2 2 2 0 MYST family zinc finger domain zf-H2C2_5 PF13909.6 KFM73618.1 - 4.1 7.2 15.7 5.9 6.7 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Diphthamide_syn PF01866.17 KFM73619.1 - 1.2e-41 143.1 0.3 1.6e-41 142.7 0.3 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Tnp_P_element PF12017.8 KFM73620.1 - 2.1e-11 43.7 0.1 3e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Transposase protein Fer2_3 PF13085.6 KFM73622.1 - 0.12 12.4 0.4 0.28 11.2 0.1 1.8 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DUF5526 PF17664.1 KFM73622.1 - 1.3 8.6 14.5 0.17 11.4 9.4 1.9 1 1 0 2 2 2 0 Family of unknown function (DUF5526) DUF4200 PF13863.6 KFM73622.1 - 2.9 8.3 26.0 0.5 10.8 14.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF3552 PF12072.8 KFM73622.1 - 4.9 6.5 18.6 0.75 9.2 11.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) eIF_4EBP PF05456.11 KFM73624.1 - 0.088 12.8 0.0 0.089 12.7 0.0 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) EIF4E-T PF10477.9 KFM73624.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.3 1 1 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E WAP PF00095.21 KFM73625.1 - 1.4e-05 25.3 12.4 1.4e-05 25.3 12.4 2.3 4 0 0 4 4 4 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Hormone_3 PF00159.18 KFM73625.1 - 0.0093 16.0 0.2 0.016 15.2 0.2 1.4 1 0 0 1 1 1 1 Pancreatic hormone peptide RNase_H PF00075.24 KFM73627.1 - 5e-12 46.2 0.0 1.4e-10 41.6 0.0 2.6 2 1 0 2 2 2 1 RNase H Exo_endo_phos_2 PF14529.6 KFM73627.1 - 5.7e-10 39.1 0.4 2.7e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DDE_3 PF13358.6 KFM73628.1 - 2.1e-08 34.0 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease EF-hand_1 PF00036.32 KFM73629.1 - 5.3e-31 103.8 12.7 2.5e-09 36.0 1.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFM73629.1 - 2.2e-28 98.5 11.5 1.5e-18 67.0 3.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM73629.1 - 6.1e-25 85.0 10.5 3.4e-08 32.8 0.0 4.4 3 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFM73629.1 - 8.2e-20 70.4 15.4 2.7e-12 46.3 3.8 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KFM73629.1 - 2.8e-18 66.0 1.1 7.7e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFM73629.1 - 6.8e-14 50.6 13.8 7.6e-05 22.0 0.9 4.6 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 KFM73629.1 - 1.1e-06 28.5 2.3 0.012 15.5 0.4 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KFM73629.1 - 0.00085 19.3 1.6 3 7.8 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein ERAP1_C PF11838.8 KFM73629.1 - 0.011 15.3 0.1 0.66 9.5 0.0 2.2 1 1 1 2 2 2 0 ERAP1-like C-terminal domain DUF2059 PF09832.9 KFM73629.1 - 0.012 15.7 2.7 0.6 10.2 0.2 2.7 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2059) EF-hand_11 PF08976.11 KFM73629.1 - 0.034 15.0 0.3 7.9 7.4 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain DUF2666 PF10869.8 KFM73629.1 - 0.036 14.3 0.3 4.3 7.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Glutaredoxin PF00462.24 KFM73629.1 - 0.037 14.3 0.5 0.57 10.4 0.0 2.6 2 1 1 3 3 3 0 Glutaredoxin DUF2179 PF10035.9 KFM73629.1 - 0.038 13.8 0.7 0.49 10.2 0.0 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF3024 PF11225.8 KFM73629.1 - 0.044 14.1 2.3 17 5.8 0.0 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3024) Ribosomal_S20p PF01649.18 KFM73629.1 - 0.065 13.9 0.0 30 5.4 0.0 2.8 2 1 1 3 3 3 0 Ribosomal protein S20 SPARC_Ca_bdg PF10591.9 KFM73629.1 - 0.068 13.5 2.0 0.83 10.0 0.1 2.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GPHH PF16905.5 KFM73629.1 - 0.071 12.9 0.1 5.3 6.9 0.0 3.0 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated DUF3349 PF11829.8 KFM73629.1 - 0.082 13.7 2.4 4.7 8.1 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF1722 PF08349.11 KFM73629.1 - 0.096 13.0 0.0 6.3 7.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) DUF5580 PF17743.1 KFM73629.1 - 0.14 10.6 0.0 0.7 8.4 0.0 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5580) MgtE_N PF03448.17 KFM73629.1 - 0.67 10.6 7.2 0.88 10.2 0.8 2.5 1 1 1 2 2 2 0 MgtE intracellular N domain NIF PF03031.18 KFM73630.1 - 4.1e-49 166.3 0.0 5.4e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Lyase_1 PF00206.20 KFM73631.1 - 1.3e-117 392.6 0.0 1.7e-117 392.3 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KFM73631.1 - 1.1e-27 96.2 0.2 3.5e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 Fumarase C C-terminus AAA PF00004.29 KFM73632.1 - 1.5e-42 145.2 0.0 3.8e-42 143.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM73632.1 - 1e-11 44.5 0.6 1.9e-11 43.5 0.6 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFM73632.1 - 5.5e-11 42.2 0.2 1.2e-10 41.1 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KFM73632.1 - 7.1e-07 29.5 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFM73632.1 - 1.9e-06 28.2 0.1 0.0012 19.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFM73632.1 - 2e-05 23.9 0.0 3.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFM73632.1 - 4.7e-05 23.2 0.0 9.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM73632.1 - 5e-05 23.7 0.1 0.0022 18.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFM73632.1 - 5.4e-05 23.2 0.4 0.00046 20.2 0.2 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Prot_ATP_OB_N PF17758.1 KFM73632.1 - 0.00037 20.1 0.1 0.0015 18.2 0.0 2.1 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 KFM73632.1 - 0.0018 17.9 0.6 0.27 10.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFM73632.1 - 0.0019 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFM73632.1 - 0.0023 18.5 0.5 0.0042 17.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KFM73632.1 - 0.0028 17.8 0.0 0.006 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFM73632.1 - 0.0029 17.0 0.1 0.17 11.2 0.0 2.7 2 1 1 3 3 3 1 KaiC RNA_helicase PF00910.22 KFM73632.1 - 0.0043 17.4 0.0 0.011 16.1 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_28 PF13521.6 KFM73632.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFM73632.1 - 0.0093 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KFM73632.1 - 0.011 15.2 0.0 0.061 12.8 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.13 KFM73632.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KFM73632.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFM73632.1 - 0.022 14.6 0.1 0.078 12.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFM73632.1 - 0.032 13.9 0.8 0.072 12.8 0.2 1.9 2 1 0 2 2 1 0 AAA domain SKI PF01202.22 KFM73632.1 - 0.033 14.3 0.0 8.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_17 PF13207.6 KFM73632.1 - 0.037 14.4 0.2 0.54 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFM73632.1 - 0.038 13.7 0.2 0.12 12.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM73632.1 - 0.047 13.6 0.0 0.45 10.4 0.0 2.2 1 1 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KFM73632.1 - 0.049 13.1 1.5 0.071 12.6 0.1 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 KFM73632.1 - 0.068 12.9 0.1 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM73632.1 - 0.078 13.5 0.1 0.22 12.0 0.1 2.1 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 KFM73632.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KFM73632.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KFM73632.1 - 0.11 12.3 0.3 1.3 8.8 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFM73632.1 - 0.11 11.6 0.0 0.4 9.8 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 KFM73632.1 - 0.13 12.0 0.0 0.44 10.2 0.0 1.9 3 0 0 3 3 2 0 Sigma-54 interaction domain HTH_Tnp_Tc3_2 PF01498.18 KFM73633.1 - 2.2e-08 34.2 0.2 2.4e-08 34.1 0.2 1.0 1 0 0 1 1 1 1 Transposase CDRN PF05174.12 KFM73633.1 - 0.28 10.9 3.8 0.38 10.5 3.8 1.3 1 1 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus T_cell_tran_alt PF15128.6 KFM73634.1 - 0.021 14.6 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 T-cell leukemia translocation-altered NRIP1_repr_3 PF15689.5 KFM73635.1 - 0.0036 17.6 1.3 0.0058 16.9 1.0 1.5 1 1 0 1 1 1 1 Nuclear receptor-interacting protein 1 repression 3 Acyltransf_C PF16076.5 KFM73636.1 - 1.8e-14 53.6 0.2 6.4e-14 51.8 0.2 1.9 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KFM73636.1 - 7.9e-09 35.2 0.1 1.5e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase DUF4051 PF13260.6 KFM73637.1 - 0.035 13.8 1.7 0.078 12.7 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Shisa PF13908.6 KFM73637.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.6 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator ATP-synt_D PF01813.17 KFM73638.1 - 1.3e-76 256.8 5.6 1.6e-76 256.5 5.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit D AA_permease_2 PF13520.6 KFM73640.1 - 8.5e-50 169.8 39.2 1.4e-49 169.1 27.2 2.3 2 1 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFM73640.1 - 2.9e-31 108.6 29.5 2.9e-31 108.6 29.5 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFM73640.1 - 1.5e-21 76.2 7.3 1.5e-21 76.2 7.3 3.3 3 0 0 3 3 3 1 C-terminus of AA_permease DUF751 PF05421.11 KFM73640.1 - 0.32 11.8 11.7 0.95 10.2 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF751) IRF PF00605.17 KFM73641.1 - 2.5e-16 59.9 0.5 3.8e-16 59.3 0.5 1.2 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor UQ_con PF00179.26 KFM73643.1 - 2.9e-39 133.9 0.0 3.7e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM73643.1 - 0.13 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B F-box-like PF12937.7 KFM73644.1 - 2e-11 43.6 0.1 2e-11 43.6 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFM73644.1 - 1.8e-09 37.2 0.1 3.8e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFM73644.1 - 3.1e-06 27.1 1.0 7.1e-06 25.9 1.0 1.6 1 1 0 1 1 1 1 F-box F-box_5 PF18511.1 KFM73644.1 - 0.56 9.8 2.8 3.8 7.1 2.8 2.3 1 1 0 1 1 1 0 F-box Ephrin_rec_like PF07699.13 KFM73644.1 - 0.77 9.6 8.7 14 5.5 0.1 2.4 2 0 0 2 2 2 0 Putative ephrin-receptor like CCAP PF11105.8 KFM73646.1 - 0.012 15.6 0.2 0.02 14.8 0.2 1.4 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a CPL PF08144.11 KFM73646.1 - 0.12 12.7 2.2 2.6 8.4 1.5 2.0 1 1 1 2 2 2 0 CPL (NUC119) domain Glyco_transf_10 PF00852.19 KFM73647.1 - 1.3e-58 197.6 6.7 1.5e-58 197.4 6.7 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_transf_10 PF00852.19 KFM73648.1 - 2.5e-60 203.2 6.6 3e-60 202.9 6.6 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term An_peroxidase PF03098.15 KFM73649.1 - 9.5e-201 667.9 0.0 1.4e-200 667.4 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.16 KFM73649.1 - 2.6e-77 255.0 0.0 1.7e-19 69.6 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM73649.1 - 1.6e-68 227.3 1.0 9.3e-16 58.2 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFM73649.1 - 1.3e-46 156.8 0.0 8.7e-13 48.4 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFM73649.1 - 2.4e-44 149.4 0.0 3e-10 40.1 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFM73649.1 - 8.1e-25 87.1 5.9 0.00064 19.9 0.2 7.5 4 3 0 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM73649.1 - 3.5e-10 39.8 0.1 0.34 11.0 0.0 5.5 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFM73649.1 - 9.1e-10 38.4 0.0 0.14 12.2 0.1 4.7 4 0 0 4 4 4 2 C17orf99 Ig domain Ig_6 PF18452.1 KFM73649.1 - 9.6e-08 31.5 0.3 1.2 8.8 0.0 4.8 5 0 0 5 5 4 2 Immunoglobulin domain VWC PF00093.18 KFM73649.1 - 1e-05 25.8 21.5 1e-05 25.8 21.5 2.7 2 0 0 2 2 2 1 von Willebrand factor type C domain C2-set PF05790.15 KFM73649.1 - 0.0016 18.6 0.1 2.5 8.3 0.0 4.9 6 0 0 6 6 6 1 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 KFM73649.1 - 0.0017 18.4 0.1 1.3 9.1 0.0 3.7 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain BLOC1_2 PF10046.9 KFM73649.1 - 0.0036 17.6 0.4 0.01 16.1 0.4 1.7 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 LRRCT PF01463.24 KFM73649.1 - 0.025 15.1 0.1 0.087 13.4 0.1 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain DUF16 PF01519.16 KFM73649.1 - 0.12 12.9 1.0 0.24 11.9 0.5 1.8 2 0 0 2 2 1 0 Protein of unknown function DUF16 TILa PF12714.7 KFM73649.1 - 8.5 6.4 21.4 0.35 10.8 12.0 2.7 2 0 0 2 2 2 0 TILa domain 4HBT PF03061.22 KFM73650.1 - 5.2e-15 55.6 0.0 1.7e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 KFM73650.1 - 0.00054 20.3 0.0 0.0025 18.1 0.0 1.8 2 0 0 2 2 2 1 Thioesterase-like superfamily zf-C2H2 PF00096.26 KFM73650.1 - 0.00069 19.9 11.8 0.0077 16.6 7.6 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type FAR1 PF03101.15 KFM73650.1 - 0.0021 18.7 0.7 0.0021 18.7 0.7 1.7 2 0 0 2 2 2 1 FAR1 DNA-binding domain zf-C2H2_6 PF13912.6 KFM73650.1 - 0.0025 17.8 5.4 0.61 10.2 3.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM73650.1 - 0.0062 16.8 5.1 1.7 9.1 0.2 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFM73650.1 - 0.017 15.4 2.4 0.21 11.9 2.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM73650.1 - 0.066 13.6 2.2 0.38 11.2 2.4 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM73650.1 - 0.1 13.5 13.0 1.5 9.9 6.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM73652.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73652.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73652.1 - 1.7e-07 30.9 1.2 6.7e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73652.1 - 0.0025 17.6 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73652.1 - 2.1 9.0 15.6 0.12 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM73653.1 - 5.7e-88 295.6 0.0 7e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Acetyltransf_1 PF00583.25 KFM73654.1 - 7e-14 52.1 0.0 9.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM73654.1 - 4.3e-07 30.3 0.0 7.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM73654.1 - 1.7e-06 27.9 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KFM73654.1 - 3.2e-06 27.1 0.0 1.2e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KFM73654.1 - 0.00047 19.7 0.3 0.0025 17.3 0.4 1.9 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 KFM73654.1 - 0.006 16.7 0.0 0.04 14.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KFM73654.1 - 0.05 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 KFM73654.1 - 0.052 14.2 0.0 0.073 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1952 PF09189.10 KFM73654.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) Acetyltransf_CG PF14542.6 KFM73654.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SURF6 PF04935.12 KFM73655.1 - 1.5e-33 116.3 50.9 1.5e-33 116.3 50.9 2.5 1 1 2 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KFM73655.1 - 5.2e-07 30.2 2.5 5.2e-07 30.2 2.5 6.4 4 1 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 TROVE PF05731.11 KFM73656.1 - 2.4e-16 59.8 3.3 2.8e-15 56.3 3.3 1.9 1 1 0 1 1 1 1 TROVE domain Sushi PF00084.20 KFM73658.1 - 1e-40 138.1 17.5 5.8e-12 46.0 1.0 4.1 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) HRM PF02793.22 KFM73658.1 - 3.6e-06 27.2 17.3 0.0017 18.6 0.2 4.7 4 1 0 4 4 4 4 Hormone receptor domain Sushi PF00084.20 KFM73659.1 - 6.7e-40 135.5 37.4 3.8e-08 33.8 0.7 8.5 9 0 0 9 9 9 8 Sushi repeat (SCR repeat) SpoU_methylas_C PF12105.8 KFM73659.1 - 0.018 14.7 0.1 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 SpoU, rRNA methylase, C-terminal cEGF PF12662.7 KFM73659.1 - 2.1 8.3 15.2 4.2 7.4 0.3 5.4 5 0 0 5 5 5 0 Complement Clr-like EGF-like Spectrin PF00435.21 KFM73660.1 - 1.8e-62 208.4 23.4 3e-23 82.3 9.1 4.3 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 KFM73660.1 - 7.4e-56 187.0 1.7 1.9e-28 98.8 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFM73660.1 - 3.1e-28 97.7 0.0 1.3e-27 95.7 0.0 2.2 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 KFM73660.1 - 1.6e-10 39.7 0.1 0.0007 19.0 0.0 3.3 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.8 KFM73660.1 - 3.4e-10 39.6 0.1 1.5e-08 34.4 0.1 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_6 PF13405.6 KFM73660.1 - 7.1e-07 28.7 0.4 0.0021 17.8 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFM73660.1 - 3.9e-06 27.2 0.5 3.2e-05 24.3 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFM73660.1 - 0.00016 21.4 0.1 0.0033 17.3 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair Aminotran_1_2 PF00155.21 KFM73661.1 - 1.7e-16 60.4 0.0 2.3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1759 PF03564.15 KFM73662.1 - 8.3e-26 90.7 4.9 8.3e-26 90.7 4.9 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1759) HBM PF16591.5 KFM73662.1 - 0.097 12.1 1.3 0.4 10.1 0.1 2.2 2 0 0 2 2 2 0 Helical bimodular sensor domain PTPlike_phytase PF14566.6 KFM73662.1 - 0.098 12.8 0.1 0.26 11.4 0.1 1.8 1 1 0 1 1 1 0 Inositol hexakisphosphate DUF4298 PF14131.6 KFM73662.1 - 0.48 10.4 5.6 0.45 10.5 0.5 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF4298) UQ_con PF00179.26 KFM73663.1 - 1.9e-17 63.2 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM73663.1 - 0.075 13.3 0.0 0.081 13.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain Septin PF00735.18 KFM73665.1 - 1.1e-122 408.7 0.0 1.1e-122 408.7 0.0 2.1 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFM73665.1 - 2.8e-07 30.6 1.0 8.3e-07 29.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFM73665.1 - 0.00056 19.3 0.0 0.00056 19.3 0.0 2.2 2 1 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KFM73665.1 - 0.00086 19.3 0.4 0.00086 19.3 0.4 3.1 3 1 0 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 KFM73665.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 2.6 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KFM73665.1 - 0.0049 17.4 3.5 0.078 13.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Ras PF00071.22 KFM73665.1 - 0.0069 16.0 0.2 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KFM73665.1 - 0.017 15.5 0.5 0.068 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KFM73665.1 - 0.028 14.7 0.0 0.09 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM73665.1 - 0.041 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KFM73665.1 - 0.048 13.9 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Coiled-coil_56 PF09813.9 KFM73665.1 - 0.058 13.4 4.9 8.5 6.5 6.2 3.0 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 56 AAA_7 PF12775.7 KFM73665.1 - 0.076 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Unstab_antitox PF09720.10 KFM73665.1 - 0.084 12.9 1.5 0.19 11.8 1.5 1.5 1 0 0 1 1 1 0 Putative addiction module component FeoB_N PF02421.18 KFM73665.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B Exonuc_VII_L PF02601.15 KFM73665.1 - 0.33 10.5 10.6 0.51 9.9 10.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 KFM73665.1 - 0.62 10.1 4.2 19 5.2 3.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain LMBR1 PF04791.16 KFM73665.1 - 1.2 8.0 4.3 1.8 7.4 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Shisa PF13908.6 KFM73666.1 - 0.0027 18.0 1.2 0.0027 18.0 1.2 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Ni_hydr_CYTB PF01292.20 KFM73666.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Chordopox_G3 PF06129.12 KFM73666.1 - 0.14 12.9 0.1 0.14 12.9 0.1 1.6 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Orf78 PF06024.12 KFM73666.1 - 0.81 10.0 2.7 2 8.8 0.5 2.0 2 0 0 2 2 2 0 Orf78 (ac78) DUF4389 PF14333.6 KFM73666.1 - 7.7 6.5 6.9 3.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Arif-1 PF06770.11 KFM73667.1 - 0.00062 19.5 0.1 0.00084 19.1 0.1 1.2 1 0 0 1 1 1 1 Actin-rearrangement-inducing factor (Arif-1) DDE_3 PF13358.6 KFM73669.1 - 0.003 17.3 0.0 0.0068 16.2 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease ETRAMP PF09716.10 KFM73673.1 - 0.22 11.6 0.6 0.33 11.0 0.6 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ldl_recept_a PF00057.18 KFM73673.1 - 0.39 11.0 6.2 0.57 10.4 6.2 1.3 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A WD40 PF00400.32 KFM73674.1 - 2.9e-21 75.4 12.4 0.0003 21.5 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM73674.1 - 2.9e-09 37.1 3.8 0.16 12.3 0.1 4.8 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM73674.1 - 2.9e-06 26.8 0.0 0.00015 21.2 0.0 2.1 1 1 1 2 2 2 2 WD40-like domain DUF3368 PF11848.8 KFM73676.1 - 0.2 11.5 0.0 0.2 11.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Peptidase_M13_N PF05649.13 KFM73677.1 - 1.9e-24 87.1 0.1 1.9e-24 87.1 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M13 HTH_Tnp_Tc3_2 PF01498.18 KFM73678.1 - 1.8e-16 60.1 2.2 6.4e-16 58.4 2.2 2.0 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73678.1 - 5e-14 52.3 0.0 8.5e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73678.1 - 3.3e-07 30.0 1.6 7.8e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73678.1 - 0.0031 17.3 0.6 0.0084 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73678.1 - 3.1 8.5 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73679.1 - 3.9e-16 59.1 3.0 6.4e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73679.1 - 1.4e-13 50.9 0.0 2.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73679.1 - 3.2e-07 30.0 1.6 7.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73679.1 - 0.0028 17.4 0.6 0.0083 15.9 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73679.1 - 2.7 8.7 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73681.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73681.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73681.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73681.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73681.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ubiquitin PF00240.23 KFM73682.1 - 6.1e-14 51.5 0.1 9.6e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFM73682.1 - 8.6e-05 22.3 0.2 8.6e-05 22.3 0.2 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like SAD_SRA PF02182.17 KFM73683.1 - 2.6e-57 192.9 0.2 4.8e-57 192.1 0.2 1.4 1 0 0 1 1 1 1 SAD/SRA domain TTD PF12148.8 KFM73683.1 - 3.3e-38 131.0 2.2 3.3e-38 131.0 2.2 2.5 3 0 0 3 3 3 1 Tandem tudor domain within UHRF1 PHD PF00628.29 KFM73683.1 - 1.1e-10 41.2 8.4 1.1e-10 41.2 8.4 3.4 3 0 0 3 3 3 1 PHD-finger Hep_59 PF07052.11 KFM73683.1 - 1.1 10.0 6.1 0.74 10.6 2.9 2.2 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Ank_5 PF13857.6 KFM73684.1 - 1.1e-07 32.0 0.0 4.6e-06 26.8 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM73684.1 - 2.3e-07 31.2 0.0 2.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM73684.1 - 6.3e-06 26.7 0.0 7.3e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM73684.1 - 8.7e-05 22.6 0.0 0.016 15.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KFM73684.1 - 0.00042 20.6 0.1 0.064 13.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat APG12 PF04110.13 KFM73685.1 - 4.6e-30 103.9 0.1 5.8e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KFM73685.1 - 3.8e-06 27.0 0.0 4.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like DUF2362 PF10154.9 KFM73686.1 - 3.3e-199 663.0 2.4 3.7e-199 662.8 2.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) DUF5448 PF17526.2 KFM73686.1 - 0.011 15.9 0.2 1.8 8.8 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5448) UNC-93 PF05978.16 KFM73687.1 - 2.7e-49 166.9 13.7 7.2e-49 165.5 13.7 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 ApoL PF05461.11 KFM73688.1 - 2.7e-17 63.1 0.0 1.1e-07 31.5 0.0 2.1 2 0 0 2 2 2 2 Apolipoprotein L AIP3 PF03915.13 KFM73688.1 - 0.012 14.7 1.5 0.012 14.7 1.5 1.5 2 0 0 2 2 2 0 Actin interacting protein 3 DUF4781 PF16013.5 KFM73688.1 - 0.017 13.9 2.3 0.093 11.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4781) Z1 PF10593.9 KFM73688.1 - 0.33 10.4 2.2 0.34 10.4 1.1 1.6 2 0 0 2 2 2 0 Z1 domain DDE_Tnp_1_7 PF13843.6 KFM73689.1 - 1.4e-79 267.9 3.0 1.8e-79 267.6 3.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Peptidase_M54 PF07998.11 KFM73689.1 - 0.021 14.8 0.3 0.053 13.5 0.3 1.7 1 0 0 1 1 1 0 Peptidase family M54 Pex14_N PF04695.13 KFM73689.1 - 0.06 14.0 0.4 0.13 12.9 0.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RGS PF00615.19 KFM73690.1 - 4.7e-14 52.7 4.2 3.1e-09 37.1 0.0 3.4 3 0 0 3 3 3 3 Regulator of G protein signaling domain HD-ZIP_N PF04618.12 KFM73690.1 - 0.039 14.5 1.5 0.1 13.1 1.5 1.6 1 0 0 1 1 1 0 HD-ZIP protein N terminus CotE PF10628.9 KFM73690.1 - 0.082 12.5 1.6 0.12 12.0 0.9 1.5 1 1 0 1 1 1 0 Outer spore coat protein E (CotE) REC114-like PF15165.6 KFM73692.1 - 7.7e-23 81.5 0.1 5.3e-20 72.2 0.0 2.0 1 1 1 2 2 2 2 Meiotic recombination protein REC114-like IATP PF04568.12 KFM73693.1 - 2.8e-25 88.6 1.5 2.9e-25 88.5 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PI3Ka PF00613.20 KFM73694.1 - 7.7e-57 191.7 1.5 7.7e-57 191.7 1.5 2.0 3 0 0 3 3 3 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFM73694.1 - 9.4e-56 189.4 0.7 4.4e-55 187.2 0.7 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_p85B PF02192.16 KFM73694.1 - 1.5e-30 104.7 0.1 3.6e-30 103.5 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 KFM73694.1 - 1.1e-26 93.1 0.4 1.8e-25 89.2 0.3 2.5 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFM73694.1 - 9.6e-22 77.4 0.0 2.1e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Tim17 PF02466.19 KFM73695.1 - 0.15 12.5 7.9 0.22 11.9 7.5 1.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Bystin PF05291.11 KFM73696.1 - 6.7e-41 140.5 0.2 7.3e-41 140.4 0.2 1.0 1 0 0 1 1 1 1 Bystin CTP_synth_N PF06418.14 KFM73696.1 - 0.077 12.3 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 CTP synthase N-terminus NUC130_3NT PF08158.12 KFM73696.1 - 0.086 13.2 0.1 0.23 11.8 0.1 1.6 2 0 0 2 2 2 0 NUC130/3NT domain Bystin PF05291.11 KFM73697.1 - 3.6e-36 124.9 0.7 3.9e-36 124.8 0.7 1.0 1 0 0 1 1 1 1 Bystin Bap31 PF05529.12 KFM73698.1 - 6.7e-44 149.0 4.9 6.7e-44 149.0 4.9 1.6 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KFM73698.1 - 3.8e-13 49.2 12.4 3.8e-13 49.2 12.4 3.0 2 1 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Fib_alpha PF08702.10 KFM73698.1 - 5.9e-05 23.3 8.3 5.9e-05 23.3 8.3 1.7 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF812 PF05667.11 KFM73698.1 - 0.00054 19.0 11.4 0.00066 18.7 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF4407 PF14362.6 KFM73698.1 - 0.0032 16.9 9.6 0.0052 16.2 9.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FAM184 PF15665.5 KFM73698.1 - 0.0049 16.7 22.8 0.0088 15.8 22.8 1.4 1 1 0 1 1 1 1 Family with sequence similarity 184, A and B DUF4515 PF14988.6 KFM73698.1 - 0.0077 16.1 15.8 0.0077 16.1 15.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) LCIB_C_CA PF18599.1 KFM73698.1 - 0.014 14.7 3.1 0.021 14.1 3.1 1.3 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF3498 PF12004.8 KFM73698.1 - 0.021 14.0 10.3 0.024 13.9 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) DUF4337 PF14235.6 KFM73698.1 - 0.03 14.5 8.6 0.05 13.7 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Spc7 PF08317.11 KFM73698.1 - 0.033 13.1 19.7 0.06 12.2 19.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein MPS2 PF17060.5 KFM73698.1 - 0.045 13.0 12.4 0.067 12.4 12.4 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Tropomyosin_1 PF12718.7 KFM73698.1 - 0.054 13.7 24.7 0.092 12.9 24.7 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF724 PF05266.14 KFM73698.1 - 0.11 12.3 15.1 0.21 11.4 15.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cluap1 PF10234.9 KFM73698.1 - 0.52 9.7 18.9 0.93 8.8 18.9 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 Exonuc_VII_L PF02601.15 KFM73698.1 - 0.78 9.3 13.6 1.4 8.5 13.6 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Rootletin PF15035.6 KFM73698.1 - 0.84 9.6 22.7 0.21 11.6 19.2 1.6 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion GP24_25 PF17388.2 KFM73698.1 - 0.92 9.5 6.3 0.21 11.5 2.0 1.9 1 1 1 2 2 2 0 Tail assembly gene products 24 & 25 DUF1664 PF07889.12 KFM73698.1 - 1.1 9.3 5.4 2.4 8.2 4.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 KFM73698.1 - 1.4 6.3 21.5 0.6 7.6 10.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) FapA PF03961.13 KFM73698.1 - 1.4 7.4 11.9 2 6.9 11.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tmemb_18A PF09771.9 KFM73698.1 - 1.4 9.3 3.9 3.2 8.2 2.5 2.0 1 1 1 2 2 2 0 Transmembrane protein 188 EMP24_GP25L PF01105.24 KFM73698.1 - 1.5 8.7 6.2 3.3 7.6 6.2 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SHE3 PF17078.5 KFM73698.1 - 1.7 8.3 19.2 0.048 13.4 9.1 2.3 2 1 1 3 3 2 0 SWI5-dependent HO expression protein 3 Phage_Mu_Gam PF07352.12 KFM73698.1 - 1.8 8.5 16.0 1.3 8.9 13.1 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Sec34 PF04136.15 KFM73698.1 - 2 8.3 12.1 2.3 8.1 5.2 2.3 1 1 1 2 2 2 0 Sec34-like family DUF2564 PF10819.8 KFM73698.1 - 2.3 8.6 10.4 1.3 9.5 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) DUF3450 PF11932.8 KFM73698.1 - 2.7 7.3 17.8 2.7 7.2 16.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 KFM73698.1 - 3.1 8.1 8.6 5 7.5 1.2 2.8 3 1 0 3 3 1 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 KFM73698.1 - 4.1 7.5 30.1 0.064 13.3 17.0 3.0 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 KFM73698.1 - 4.5 7.8 31.6 2.2 8.8 27.5 2.2 1 1 1 2 2 1 0 Apg6 coiled-coil region CRA PF06589.11 KFM73698.1 - 5.1 7.2 12.7 3.5 7.7 9.5 2.2 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) V_ATPase_I PF01496.19 KFM73698.1 - 5.3 4.8 17.3 0.36 8.7 12.2 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 KFM73698.1 - 5.5 6.0 13.9 8 5.4 13.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Glutaredoxin2_C PF04399.13 KFM73698.1 - 5.6 6.8 8.2 7 6.5 2.3 2.5 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain RIC3 PF15361.6 KFM73698.1 - 5.9 7.3 12.6 13 6.2 12.6 1.9 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 FUSC PF04632.12 KFM73698.1 - 7.3 5.0 10.5 0.36 9.3 5.3 1.6 2 1 0 2 2 2 0 Fusaric acid resistance protein family HIP1_clath_bdg PF16515.5 KFM73698.1 - 7.6 7.2 22.3 2.9 8.6 17.6 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Phage_lysozyme2 PF18013.1 KFM73698.1 - 8.1 6.5 9.4 2.8 7.9 1.5 2.2 1 1 1 2 2 2 0 Phage tail lysozyme SOAR PF16533.5 KFM73698.1 - 8.5 6.4 14.9 28 4.8 11.3 2.9 1 1 0 2 2 2 0 STIM1 Orai1-activating region Nup88 PF10168.9 KFM73698.1 - 8.7 4.0 13.7 13 3.5 13.7 1.3 1 0 0 1 1 1 0 Nuclear pore component DUF3899 PF13038.6 KFM73699.1 - 0.00059 20.3 0.7 0.0077 16.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3899) Flp1_like PF16982.5 KFM73699.1 - 0.0042 16.4 2.2 0.0087 15.4 2.2 1.6 1 0 0 1 1 1 1 Putative Flagellin, Flp1-like, domain DUF4366 PF14283.6 KFM73699.1 - 0.022 14.8 0.5 0.054 13.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) LRR19-TM PF15176.6 KFM73699.1 - 0.022 14.7 0.1 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Glt_symporter PF03616.14 KFM73699.1 - 0.022 13.4 0.2 0.032 12.9 0.2 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter EphA2_TM PF14575.6 KFM73699.1 - 0.024 15.5 0.0 1.4 9.9 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2304 PF10066.9 KFM73699.1 - 0.036 14.3 2.2 1.9 8.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) SID-1_RNA_chan PF13965.6 KFM73699.1 - 0.038 12.4 0.1 0.045 12.2 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Orf78 PF06024.12 KFM73699.1 - 0.042 14.2 0.9 0.084 13.2 0.4 1.8 1 1 1 2 2 2 0 Orf78 (ac78) DUF3149 PF11346.8 KFM73699.1 - 0.044 13.4 1.5 0.044 13.4 1.5 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3149) Ni_hydr_CYTB PF01292.20 KFM73699.1 - 0.054 13.1 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4448 PF14610.6 KFM73699.1 - 0.072 12.9 0.3 0.62 9.8 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) DUF3377 PF11857.8 KFM73699.1 - 0.097 12.6 0.0 0.097 12.6 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF3377) SARAF PF06682.12 KFM73699.1 - 0.12 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1180 PF06679.12 KFM73699.1 - 0.14 12.5 3.9 0.29 11.5 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) PBP1_TM PF14812.6 KFM73699.1 - 0.21 12.0 1.3 1.7 9.1 0.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ig_3 PF13927.6 KFM73701.1 - 0.0032 18.0 0.4 0.0032 18.0 0.4 1.7 2 0 0 2 2 2 1 Immunoglobulin domain RCC1_2 PF13540.6 KFM73701.1 - 0.0064 16.3 0.3 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat ig PF00047.25 KFM73701.1 - 0.042 14.0 0.2 0.042 14.0 0.2 1.7 2 0 0 2 2 2 0 Immunoglobulin domain DUF2828 PF11443.8 KFM73702.1 - 0.027 12.6 2.2 0.026 12.6 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GatB_N PF02934.15 KFM73703.1 - 2.4e-39 135.4 0.0 3.3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KFM73703.1 - 4.6e-07 29.8 0.0 8.4e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 GatB domain GatB_N PF02934.15 KFM73704.1 - 8.6e-48 163.1 0.0 9.9e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 GatB/GatE catalytic domain Dna2 PF08696.11 KFM73706.1 - 9.2e-52 175.8 1.4 2.2e-51 174.6 1.4 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 KFM73706.1 - 1.6e-33 116.6 1.5 4.2e-19 69.3 0.1 2.7 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 KFM73706.1 - 5.3e-12 46.3 0.1 1.1e-11 45.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM73706.1 - 9.8e-12 45.0 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KFM73706.1 - 3.6e-10 40.2 0.0 6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 KFM73706.1 - 9.1e-05 22.3 0.4 0.3 10.8 0.0 2.7 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 KFM73706.1 - 0.00011 22.3 4.9 0.053 13.6 1.5 3.2 2 1 0 2 2 2 2 Domain of unknown function DUF83 UvrD-helicase PF00580.21 KFM73706.1 - 0.0019 17.8 2.5 0.55 9.7 0.2 3.0 2 1 0 3 3 3 2 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KFM73706.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_18 PF13238.6 KFM73706.1 - 0.011 16.3 0.0 0.043 14.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KFM73706.1 - 0.013 15.1 0.1 0.04 13.5 0.1 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF853 PF05872.12 KFM73706.1 - 0.021 13.4 0.1 0.034 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF2075 PF09848.9 KFM73706.1 - 0.026 13.8 0.1 0.061 12.6 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_6 PF12774.7 KFM73706.1 - 0.037 13.0 0.7 5.7 5.8 0.0 2.6 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 KFM73706.1 - 0.057 12.9 0.4 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 KFM73706.1 - 0.094 11.8 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KFM73706.1 - 0.1 12.4 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.23 KFM73706.1 - 0.12 12.4 2.7 0.47 10.5 0.6 2.7 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 KFM73706.1 - 0.12 12.3 0.4 0.44 10.5 0.5 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 KFM73706.1 - 0.14 12.6 0.7 0.41 11.1 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KFM73706.1 - 0.16 11.5 8.6 0.27 10.8 0.8 2.8 3 0 0 3 3 3 0 AAA domain cwf21 PF08312.12 KFM73706.1 - 0.22 11.7 1.9 0.59 10.3 1.9 1.7 1 0 0 1 1 1 0 cwf21 domain NTPase_1 PF03266.15 KFM73706.1 - 0.48 10.3 6.3 0.96 9.3 0.4 3.4 4 0 0 4 4 4 0 NTPase DUF87 PF01935.17 KFM73706.1 - 1.1 9.3 3.3 1.7 8.7 1.1 2.3 2 1 0 2 2 2 0 Helicase HerA, central domain L51_S25_CI-B8 PF05047.16 KFM73708.1 - 8.2e-06 25.7 0.1 1.2e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HTH_Tnp_Tc3_2 PF01498.18 KFM73709.1 - 2.5e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73709.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.32 KFM73710.1 - 2.1e-35 120.1 18.6 1.2e-07 32.2 2.3 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM73710.1 - 3.2e-20 72.2 1.2 2.6e-07 30.8 0.0 5.0 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM73710.1 - 2.1e-07 30.2 4.6 0.092 11.7 0.1 4.7 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFM73710.1 - 6.2e-06 25.8 0.8 0.023 14.0 0.0 3.3 2 1 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 KFM73710.1 - 6.5e-06 25.1 0.3 0.038 12.7 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFM73710.1 - 9.5e-05 21.1 0.0 0.013 14.1 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 KFM73710.1 - 0.0011 18.9 1.2 0.23 11.5 0.0 2.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF5046 PF16465.5 KFM73710.1 - 0.0036 16.8 0.0 0.05 13.0 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) IKI3 PF04762.12 KFM73710.1 - 0.012 13.7 0.0 0.019 13.0 0.0 1.3 1 0 0 1 1 1 0 IKI3 family DUF5114 PF17141.4 KFM73710.1 - 0.035 14.6 0.4 0.54 10.8 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5114) VID27 PF08553.10 KFM73710.1 - 0.053 12.6 0.1 0.61 9.1 0.1 2.1 1 1 0 2 2 2 0 VID27 C-terminal WD40-like domain PALB2_WD40 PF16756.5 KFM73710.1 - 0.054 12.4 0.8 1 8.2 0.0 2.6 2 2 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Big_3_5 PF16640.5 KFM73710.1 - 0.12 12.5 0.2 0.34 11.1 0.1 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Sugar_tr PF00083.24 KFM73711.1 - 1.6e-18 66.8 3.6 2.2e-18 66.3 3.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Sec1 PF00995.23 KFM73712.1 - 8.2e-123 411.6 0.3 9.2e-123 411.5 0.3 1.0 1 0 0 1 1 1 1 Sec1 family CCDC117 PF15810.5 KFM73713.1 - 6.9e-05 23.2 1.3 0.00012 22.4 1.3 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 117 PPDFL PF15060.6 KFM73713.1 - 0.04 14.4 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 Differentiation and proliferation regulator Oxysterol_BP PF01237.18 KFM73714.1 - 2.1e-112 375.6 2.0 2.4e-112 375.5 2.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF1107 PF06526.12 KFM73714.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1107) WRC PF08879.10 KFM73714.1 - 0.29 10.8 8.9 0.49 10.1 0.1 2.9 3 0 0 3 3 3 0 WRC MACPF PF01823.19 KFM73716.1 - 0.035 14.2 0.1 0.078 13.1 0.1 1.8 1 1 1 2 2 2 0 MAC/Perforin domain PAN_1 PF00024.26 KFM73717.1 - 0.0002 21.3 0.1 0.00034 20.5 0.1 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KFM73717.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 PAN domain YebG PF07130.12 KFM73717.1 - 0.049 13.5 0.5 0.23 11.3 0.7 1.9 2 0 0 2 2 2 0 YebG protein MS_channel PF00924.18 KFM73717.1 - 0.076 12.6 0.1 6.6 6.2 0.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel DUF4874 PF16173.5 KFM73717.1 - 0.097 12.3 0.4 0.18 11.5 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4874) SID PF11778.8 KFM73717.1 - 0.12 12.5 0.6 0.61 10.2 0.2 2.0 2 0 0 2 2 2 0 Septation initiation EF-hand_6 PF13405.6 KFM73718.1 - 6.1e-06 25.8 3.7 0.017 15.0 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFM73718.1 - 7.8e-06 26.3 4.4 1.3e-05 25.5 2.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM73718.1 - 3e-05 23.2 4.5 0.0023 17.3 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFM73718.1 - 0.00025 20.8 5.3 0.16 11.9 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM73718.1 - 0.01 15.3 0.1 0.01 15.3 0.1 1.8 2 0 0 2 2 2 0 EF hand Polysacc_deac_1 PF01522.21 KFM73718.1 - 0.034 14.1 2.0 3.7 7.5 0.4 2.1 2 0 0 2 2 2 0 Polysaccharide deacetylase AAA_29 PF13555.6 KFM73719.1 - 0.006 16.3 0.0 0.0077 16.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KFM73719.1 - 0.077 12.3 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 KFM73719.1 - 0.13 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Helicase_RecD PF05127.14 KFM73719.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Helicase Y_phosphatase PF00102.27 KFM73719.1 - 0.17 11.4 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HEAT PF02985.22 KFM73721.1 - 8.2e-24 81.7 18.8 0.00021 21.3 0.1 11.1 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.6 KFM73721.1 - 6.3e-11 42.5 1.0 0.16 12.4 0.0 5.6 4 2 1 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 KFM73721.1 - 0.00081 19.8 5.4 34 5.1 0.0 6.9 7 1 1 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFM73721.1 - 0.0068 17.0 7.3 1.6 9.4 0.0 5.3 5 2 1 6 6 6 2 Vacuolar 14 Fab1-binding region WRNPLPNID PF15017.6 KFM73721.1 - 0.017 16.0 3.0 0.017 16.0 3.0 3.4 2 2 0 2 2 2 0 Putative WW-binding domain and destruction box SCAMP PF04144.13 KFM73722.1 - 3.1e-45 154.6 26.3 3.7e-45 154.3 26.3 1.1 1 0 0 1 1 1 1 SCAMP family DUF1077 PF06417.12 KFM73722.1 - 0.65 10.0 7.1 0.2 11.7 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) MFS_MOT1 PF16983.5 KFM73722.1 - 0.74 10.2 11.3 0.16 12.4 7.5 2.0 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily zf-C2HC_2 PF13913.6 KFM73723.1 - 1.3e-11 44.1 3.1 1.3e-11 44.1 3.1 2.6 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KFM73723.1 - 0.34 11.9 0.6 0.34 11.9 0.6 2.1 2 1 0 2 2 2 0 C2H2-type zinc finger Bcl-2 PF00452.19 KFM73724.1 - 1.1e-07 32.4 0.2 1.8e-07 31.8 0.2 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family ANXA2R PF15721.5 KFM73724.1 - 0.011 16.3 0.1 0.015 15.9 0.1 1.1 1 0 0 1 1 1 0 Annexin-2 receptor ApoLp-III PF07464.11 KFM73725.1 - 9e-05 22.6 9.3 0.00027 21.0 9.3 1.7 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Focal_AT PF03623.13 KFM73725.1 - 0.0013 18.7 3.9 0.0023 17.9 3.9 1.4 1 0 0 1 1 1 1 Focal adhesion targeting region Prominin PF05478.11 KFM73725.1 - 0.0017 16.4 3.8 0.002 16.2 3.8 1.0 1 0 0 1 1 1 1 Prominin Apolipoprotein PF01442.18 KFM73725.1 - 0.0028 17.5 4.7 0.0039 17.1 4.7 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM73725.1 - 0.0039 17.3 2.0 0.0094 16.0 2.0 1.5 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus OTCace_N PF02729.21 KFM73725.1 - 0.0076 16.3 0.6 0.012 15.6 0.6 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain MCPsignal PF00015.21 KFM73725.1 - 0.012 15.4 5.3 0.023 14.5 5.3 1.5 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain REF PF05755.12 KFM73725.1 - 0.014 15.2 1.6 0.02 14.7 1.6 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) UvrA_inter PF17760.1 KFM73725.1 - 0.023 14.7 1.1 0.039 14.0 1.1 1.4 1 0 0 1 1 1 0 UvrA interaction domain GLE1 PF07817.13 KFM73725.1 - 0.025 13.8 0.5 0.037 13.2 0.5 1.4 1 0 0 1 1 1 0 GLE1-like protein Syntaxin_2 PF14523.6 KFM73725.1 - 0.029 14.7 4.3 0.2 12.1 3.3 2.3 1 1 1 2 2 2 0 Syntaxin-like protein BAR_3_WASP_bdg PF10456.9 KFM73725.1 - 0.049 13.1 0.2 0.06 12.8 0.2 1.2 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein IZUMO PF15005.6 KFM73725.1 - 0.055 14.0 1.6 0.077 13.5 1.6 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated DUF3086 PF11285.8 KFM73725.1 - 0.085 11.9 1.3 0.1 11.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) HSCB_C PF07743.13 KFM73725.1 - 0.37 11.3 2.4 1.4 9.5 2.4 2.0 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF3461 PF11944.8 KFM73725.1 - 0.41 10.8 4.0 0.57 10.3 3.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) DUF948 PF06103.11 KFM73725.1 - 0.46 10.8 4.9 1.7 9.0 4.9 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CdvA PF18822.1 KFM73725.1 - 2.4 8.0 8.1 1.9 8.3 1.3 2.8 2 1 1 3 3 3 0 CdvA-like coiled-coil domain BCAS2 PF05700.11 KFM73725.1 - 3.7 7.2 7.2 8.9 6.0 5.2 2.1 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DegQ PF08181.11 KFM73725.1 - 6.1 7.0 6.3 7.5 6.7 0.1 3.1 2 1 2 4 4 3 0 DegQ (SacQ) family DDE_3 PF13358.6 KFM73726.1 - 0.004 16.9 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 KFM73727.1 - 5.5e-27 95.0 1.6 6.6e-27 94.7 1.6 1.1 1 0 0 1 1 1 1 Transposase IS4 NAGidase PF07555.13 KFM73728.1 - 1.5e-19 70.4 0.0 2.2e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Acetyltransf_4 PF13420.7 KFM73728.1 - 0.00092 19.4 0.0 0.0044 17.2 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain NAGidase PF07555.13 KFM73729.1 - 3.5e-30 105.4 0.1 4e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase DDE_3 PF13358.6 KFM73731.1 - 1.9e-10 40.6 0.0 2.5e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Amidase02_C PF12123.8 KFM73731.1 - 0.23 11.2 1.6 0.4 10.4 1.6 1.3 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase SAM_1 PF00536.30 KFM73732.1 - 1.4e-10 41.4 0.0 2.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM73732.1 - 2.7e-08 33.8 0.0 5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KFM73732.1 - 0.0002 21.5 0.4 0.0051 17.0 0.0 2.3 2 0 0 2 2 2 1 Ste50p, sterile alpha motif zf-FCS PF06467.14 KFM73734.1 - 4.4e-05 23.3 1.9 4.4e-05 23.3 1.9 1.7 2 1 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif SLED PF12140.8 KFM73735.1 - 4e-35 120.7 0.0 7.4e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 SLED domain MBT PF02820.18 KFM73735.1 - 1.6e-13 50.8 0.1 3e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 mbt repeat SAM_1 PF00536.30 KFM73735.1 - 1.4e-12 47.8 0.4 2.1e-12 47.3 0.4 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM73735.1 - 0.00033 20.7 0.1 0.00068 19.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFM73735.1 - 0.00049 20.0 0.0 0.00096 19.1 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ibs_toxin PF13956.6 KFM73736.1 - 0.0096 15.9 0.3 0.0096 15.9 0.3 2.6 3 0 0 3 3 3 1 Toxin Ibs, type I toxin-antitoxin system FHA PF00498.26 KFM73737.1 - 2.6e-19 69.3 0.2 6.8e-19 68.0 0.2 1.8 1 0 0 1 1 1 1 FHA domain G-patch PF01585.23 KFM73737.1 - 6.6e-11 41.9 1.5 1.3e-10 41.0 1.5 1.5 1 0 0 1 1 1 1 G-patch domain Yop-YscD_cpl PF16697.5 KFM73737.1 - 1.6e-08 34.8 0.0 4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain G-patch_2 PF12656.7 KFM73737.1 - 0.017 15.2 0.3 0.017 15.2 0.3 2.8 2 1 1 3 3 3 0 G-patch domain OCRE PF17780.1 KFM73738.1 - 2.2e-20 72.4 34.8 1.4e-15 57.1 15.9 3.3 3 0 0 3 3 3 2 OCRE domain Spc42p PF11544.8 KFM73738.1 - 0.019 14.9 0.6 0.054 13.5 0.6 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p DUF4200 PF13863.6 KFM73738.1 - 0.052 13.9 2.8 0.1 13.0 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Gly_acyl_tr_N PF06021.11 KFM73738.1 - 0.073 13.2 2.1 0.14 12.3 0.2 2.0 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Csm1_N PF18504.1 KFM73738.1 - 0.079 13.3 2.2 0.24 11.8 2.2 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain Med9 PF07544.13 KFM73738.1 - 0.59 10.3 3.6 0.83 9.8 1.8 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CKS PF01111.19 KFM73739.1 - 3.7e-38 129.6 1.8 4.3e-38 129.4 1.8 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1965 PF09248.10 KFM73739.1 - 0.026 14.3 0.1 0.04 13.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1965) WD40 PF00400.32 KFM73740.1 - 3e-17 62.7 16.8 0.00082 20.1 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM73740.1 - 0.00039 20.7 0.4 13 6.2 0.0 5.2 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM73740.1 - 0.00053 19.1 0.3 0.044 12.7 0.1 3.1 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFM73740.1 - 0.0014 18.6 0.0 0.017 15.0 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KFM73740.1 - 0.059 11.9 0.0 0.19 10.2 0.0 1.8 1 1 0 1 1 1 0 Cytochrome D1 heme domain THAP PF05485.12 KFM73741.1 - 9.1e-14 52.2 2.5 1.7e-13 51.3 2.5 1.5 1 0 0 1 1 1 1 THAP domain DUF2048 PF09752.9 KFM73742.1 - 1.7e-82 277.3 0.0 2.3e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 Abhydrolase domain containing 18 DDE_3 PF13358.6 KFM73743.1 - 9.7e-06 25.4 0.0 1e-05 25.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PPO1_DWL PF12142.8 KFM73743.1 - 0.087 12.6 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Polyphenol oxidase middle domain DUF2048 PF09752.9 KFM73744.1 - 1.8e-42 145.8 0.0 2e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Abhydrolase domain containing 18 HydF_dimer PF18128.1 KFM73744.1 - 0.062 13.4 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain DUF2205 PF10224.9 KFM73746.1 - 2.8e-28 97.7 0.2 2.8e-28 97.7 0.2 1.9 2 0 0 2 2 2 1 Short coiled-coil protein CENP-H PF05837.12 KFM73746.1 - 0.00028 21.3 0.9 0.00028 21.3 0.9 1.6 2 0 0 2 2 2 1 Centromere protein H (CENP-H) YabA PF06156.13 KFM73746.1 - 0.0019 18.8 0.7 0.0019 18.8 0.7 1.9 2 0 0 2 2 2 1 Initiation control protein YabA bZIP_1 PF00170.21 KFM73746.1 - 0.0097 16.0 2.9 0.019 15.0 2.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor FlaC_arch PF05377.11 KFM73746.1 - 0.019 15.3 3.0 0.019 15.3 3.0 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 KFM73746.1 - 0.023 14.9 6.7 0.4 10.9 1.5 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper DASH_Dad4 PF08650.10 KFM73746.1 - 0.029 14.3 1.2 0.029 14.3 1.2 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad4 ZapB PF06005.12 KFM73746.1 - 0.029 14.8 4.6 0.029 14.8 4.6 2.0 2 0 0 2 2 2 0 Cell division protein ZapB Sas10_Utp3 PF04000.15 KFM73746.1 - 0.032 14.8 0.7 0.032 14.8 0.7 1.9 2 0 0 2 2 2 0 Sas10/Utp3/C1D family FliT PF05400.13 KFM73746.1 - 0.1 13.4 3.8 0.057 14.2 1.4 1.9 1 1 1 2 2 2 0 Flagellar protein FliT DASH_Hsk3 PF08227.11 KFM73746.1 - 0.11 12.9 0.2 0.35 11.3 0.2 1.8 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DivIC PF04977.15 KFM73746.1 - 0.11 12.2 1.5 0.28 11.0 1.5 1.7 1 0 0 1 1 1 0 Septum formation initiator RabGAP-TBC PF00566.18 KFM73747.1 - 6.5e-36 124.0 5.5 1.3e-33 116.5 1.1 3.0 2 1 0 2 2 2 2 Rab-GTPase-TBC domain DDE_3 PF13358.6 KFM73749.1 - 4.1e-16 59.0 0.4 7.1e-15 55.0 0.0 2.7 1 1 2 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73749.1 - 1.7e-10 41.0 1.0 4.6e-10 39.6 1.0 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73750.1 - 1.5e-10 41.0 0.1 4.7e-05 23.2 0.1 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease MM_CoA_mutase PF01642.22 KFM73751.1 - 7.1e-241 800.2 0.0 8.5e-241 799.9 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KFM73751.1 - 1e-15 57.8 0.3 5e-15 55.6 0.1 2.2 2 0 0 2 2 2 1 B12 binding domain MCM PF00493.23 KFM73752.1 - 2.3e-70 236.2 0.0 3e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 KFM73752.1 - 2.1e-10 40.4 0.3 3.2e-08 33.2 0.1 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_lid PF17855.1 KFM73752.1 - 6.1e-08 33.0 0.3 1e-07 32.3 0.3 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 KFM73752.1 - 3.1e-07 30.5 0.0 5.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFM73752.1 - 4.4e-05 23.4 0.0 0.00012 21.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM73752.1 - 0.0015 18.2 0.0 0.019 14.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.6 KFM73752.1 - 0.031 14.6 0.1 7.5 6.9 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA PF00004.29 KFM73752.1 - 0.05 14.0 0.1 0.12 12.8 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFM73752.1 - 0.054 13.2 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KFM73752.1 - 0.096 12.6 0.1 3.7 7.4 0.0 2.3 1 1 0 2 2 2 0 NTPase AAA_22 PF13401.6 KFM73752.1 - 0.098 12.9 0.2 0.37 11.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM73752.1 - 0.11 12.9 0.1 0.21 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KFM73752.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SMC_N PF02463.19 KFM73752.1 - 0.12 11.8 0.3 16 4.8 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Vip3A_N PF12495.8 KFM73752.1 - 0.12 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Rrf2 PF02082.20 KFM73753.1 - 0.068 13.5 0.1 0.075 13.4 0.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 KFM73753.1 - 0.089 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Oxysterol_BP PF01237.18 KFM73754.1 - 5.1e-73 246.0 6.0 5.5e-71 239.4 6.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF3677 PF12432.8 KFM73755.1 - 5.1e-32 110.0 13.9 6e-32 109.8 3.0 4.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3677) Cnd1 PF12717.7 KFM73755.1 - 0.023 14.7 0.2 0.023 14.7 0.2 3.0 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HTH_Tnp_Tc3_2 PF01498.18 KFM73756.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73756.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73757.1 - 4.3e-16 58.9 3.4 5.4e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73757.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73757.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73757.1 - 0.0025 17.6 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73757.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73758.1 - 2.3e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73758.1 - 9.3e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease fn3 PF00041.21 KFM73760.1 - 2.9e-05 24.3 0.0 3.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fibronectin type III domain DDE_Tnp_4 PF13359.6 KFM73761.1 - 5.6e-27 94.4 0.0 6.7e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM73761.1 - 4.9e-08 32.8 0.0 7.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFM73761.1 - 0.036 13.7 0.0 4.7 6.8 0.0 2.1 1 1 1 2 2 2 0 Transposase DDE domain Myb_DNA-bind_5 PF13873.6 KFM73762.1 - 1.3e-13 50.8 0.0 2.2e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFM73762.1 - 0.0014 19.0 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM73762.1 - 0.0017 18.6 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2590 PF10761.9 KFM73763.1 - 0.026 14.6 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) Pkinase PF00069.25 KFM73764.1 - 1.1e-58 198.7 0.0 1.4e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73764.1 - 4.6e-28 98.2 0.0 6e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFM73764.1 - 9.3e-07 29.5 1.4 1.7e-06 28.6 1.4 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFM73764.1 - 6.4e-06 25.7 0.0 1.1e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM73764.1 - 0.009 15.0 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM73764.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM73764.1 - 0.059 12.7 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 KFM73765.1 - 5.3e-10 39.1 0.0 9.7e-10 38.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM73765.1 - 0.0045 16.7 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Prok-E2_A PF14457.6 KFM73765.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family A DUF563 PF04577.14 KFM73767.1 - 2.7e-23 83.2 0.0 4.9e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) NAD_binding_4 PF07993.12 KFM73769.1 - 3.9e-77 258.9 0.0 4.9e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 KFM73769.1 - 3e-25 88.2 0.1 8e-25 86.9 0.1 1.8 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KFM73769.1 - 5.4e-08 32.2 0.0 3.8e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFM73769.1 - 5.3e-07 29.3 0.2 4.1e-06 26.4 0.2 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM73769.1 - 2.7e-05 23.7 0.3 0.00023 20.7 0.3 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFM73769.1 - 0.00017 20.9 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PIF1 PF05970.14 KFM73771.1 - 1.9e-23 83.2 0.2 3.1e-23 82.5 0.2 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFM73771.1 - 0.014 15.1 0.1 0.029 14.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain UNC45-central PF11701.8 KFM73771.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central Sulfatase PF00884.23 KFM73772.1 - 2e-09 37.3 0.0 2e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFM73773.1 - 0.00011 22.9 0.1 0.00012 22.8 0.1 1.1 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KFM73773.1 - 0.0011 18.8 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function Ric8 PF10165.9 KFM73774.1 - 1.9e-59 201.9 0.1 2.2e-59 201.7 0.1 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Ric8 PF10165.9 KFM73775.1 - 1.3e-10 41.0 1.1 1.4e-10 40.8 1.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Ric8 PF10165.9 KFM73776.1 - 3e-28 99.1 1.7 4e-28 98.7 1.7 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Pkinase PF00069.25 KFM73778.1 - 9e-50 169.5 0.0 1.1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73778.1 - 1.3e-23 83.7 0.0 2.1e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM73778.1 - 0.00024 20.0 0.0 0.00036 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM73778.1 - 0.00079 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM73778.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM73778.1 - 0.026 13.9 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Tnp_P_element PF12017.8 KFM73780.1 - 2.6e-08 33.6 0.1 4.2e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Transposase protein Plasmodium_HRP PF05403.11 KFM73782.1 - 1.1 9.0 93.3 0.12 12.1 79.0 2.0 1 1 1 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) DDE_3 PF13358.6 KFM73783.1 - 7.8e-10 38.7 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RhoGEF PF00621.20 KFM73784.1 - 1.6e-27 96.9 0.3 2.3e-27 96.4 0.3 1.2 1 0 0 1 1 1 1 RhoGEF domain zf-RVT PF13966.6 KFM73784.1 - 0.028 15.1 0.0 0.094 13.4 0.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.18 KFM73785.1 - 5.2e-16 58.7 3.5 6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73785.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73785.1 - 2.2e-07 30.5 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73785.1 - 0.0025 17.6 0.6 0.0079 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73785.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73786.1 - 2.6e-16 59.6 2.2 4.7e-16 58.8 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73786.1 - 1.1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-ANAPC11 PF12861.7 KFM73788.1 - 1.6e-42 143.4 16.0 2e-42 143.2 16.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFM73788.1 - 5.2e-21 74.7 19.6 7.6e-21 74.2 19.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFM73788.1 - 7.5e-06 26.2 24.3 0.00011 22.5 24.1 2.3 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFM73788.1 - 0.44 10.6 15.2 0.96 9.5 13.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger SEFIR PF08357.11 KFM73789.1 - 3.3e-11 43.7 0.1 7.6e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 SEFIR domain E1-E2_ATPase PF00122.20 KFM73790.1 - 7.4e-44 149.4 1.0 7.4e-44 149.4 1.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFM73790.1 - 5.1e-23 81.0 0.0 9.6e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFM73790.1 - 8.1e-18 63.9 0.0 1.4e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFM73790.1 - 0.0028 18.0 0.0 0.026 14.8 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_efflux PF01545.21 KFM73790.1 - 0.0051 16.6 2.2 0.045 13.5 3.0 2.1 2 1 0 2 2 2 1 Cation efflux family MgtE PF01769.16 KFM73790.1 - 0.012 16.0 6.3 1.3 9.5 4.7 2.3 2 0 0 2 2 2 0 Divalent cation transporter DUF2207 PF09972.9 KFM73790.1 - 0.45 9.2 0.0 0.45 9.2 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 KFM73790.1 - 0.84 9.7 10.2 11 6.0 5.3 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Exo_endo_phos_2 PF14529.6 KFM73791.1 - 0.036 13.9 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase BAR_3 PF16746.5 KFM73792.1 - 2.1e-10 40.7 0.0 2.6e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 KFM73792.1 - 4.2e-05 23.3 0.0 4.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 BAR domain IMD PF08397.11 KFM73792.1 - 0.051 13.0 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain p450 PF00067.22 KFM73793.1 - 3.1e-32 111.9 0.2 3.1e-32 111.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 RT_RNaseH_2 PF17919.1 KFM73794.1 - 5.7e-31 106.5 0.0 1.5e-30 105.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM73794.1 - 3.4e-28 98.7 1.3 6.8e-28 97.7 0.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM73794.1 - 4.6e-28 97.6 0.0 1.4e-27 96.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM73794.1 - 6.7e-20 71.0 0.2 2.7e-19 69.0 0.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM73794.1 - 5.7e-18 65.2 0.0 1.6e-15 57.4 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KFM73794.1 - 2.5e-09 37.6 0.0 8.4e-09 35.9 0.0 2.0 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM73794.1 - 1.3e-05 25.7 0.0 3.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM73794.1 - 1.5e-05 25.2 0.0 4.5e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KFM73794.1 - 4.6e-05 23.5 1.0 0.00012 22.3 1.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KFM73794.1 - 7.4e-05 22.5 0.0 0.0002 21.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_3 PF13456.6 KFM73794.1 - 0.0023 17.7 0.1 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Asp_protease PF09668.10 KFM73794.1 - 0.003 17.4 0.1 0.0067 16.2 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease BH4 PF02180.17 KFM73794.1 - 0.056 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 BEN PF10523.9 KFM73794.1 - 0.15 12.3 0.5 3.4 8.0 0.0 3.1 2 0 0 2 2 2 0 BEN domain DEAD PF00270.29 KFM73796.1 - 1.4e-45 155.2 0.0 3.7e-45 153.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM73796.1 - 7.3e-26 90.7 0.2 1.4e-24 86.6 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain KH_1 PF00013.29 KFM73796.1 - 1.2e-15 57.1 0.9 1.2e-15 57.1 0.9 1.8 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 KFM73796.1 - 0.00075 19.3 0.2 0.0024 17.6 0.2 1.8 1 0 0 1 1 1 1 KH domain ResIII PF04851.15 KFM73796.1 - 0.0021 18.1 0.0 0.0067 16.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MOEP19 PF16005.5 KFM73796.1 - 0.0067 16.4 0.0 0.024 14.6 0.0 2.0 1 0 0 1 1 1 1 KH-like RNA-binding domain KH_5 PF13184.6 KFM73796.1 - 0.0092 16.1 0.2 0.03 14.4 0.2 1.9 1 0 0 1 1 1 1 NusA-like KH domain CMS1 PF14617.6 KFM73796.1 - 0.025 13.9 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 KFM73796.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_ScpB PF04079.16 KFM73796.1 - 0.14 11.8 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB His_Phos_2 PF00328.22 KFM73797.1 - 3.7e-18 66.1 3.6 3.1e-15 56.4 1.7 3.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-C3HC4_2 PF13923.6 KFM73798.1 - 4.2e-09 36.1 11.7 1.3e-08 34.6 11.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM73798.1 - 5e-08 33.2 10.6 5e-08 33.2 10.6 2.3 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM73798.1 - 9.5e-07 28.7 11.6 3.1e-06 27.1 11.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFM73798.1 - 1.3e-06 28.0 3.2 3.4e-06 26.7 1.8 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KFM73798.1 - 2.9e-06 27.0 10.9 9.4e-06 25.4 10.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM73798.1 - 5.2e-06 26.2 11.3 5.2e-06 26.2 11.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM73798.1 - 1e-05 25.7 9.5 4.2e-05 23.7 9.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFM73798.1 - 0.00014 21.6 10.0 0.00014 21.6 10.0 2.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFM73798.1 - 0.00019 21.4 3.5 0.00019 21.4 3.5 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFM73798.1 - 0.017 15.2 4.6 0.017 15.2 4.6 2.6 2 1 1 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 KFM73798.1 - 0.063 13.3 5.9 0.28 11.3 5.9 2.1 1 1 0 1 1 1 0 Zinc-finger DUF2615 PF11027.8 KFM73799.1 - 0.019 15.1 0.1 0.03 14.5 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) SieB PF14163.6 KFM73799.1 - 0.39 10.2 4.1 2.8 7.4 4.1 1.9 1 1 0 1 1 1 0 Super-infection exclusion protein B DUF498 PF04430.14 KFM73800.1 - 2.5e-29 101.5 0.0 3.3e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) RrnaAD PF00398.20 KFM73800.1 - 0.068 12.2 0.0 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ig_3 PF13927.6 KFM73801.1 - 8e-35 119.3 5.3 1.6e-12 47.9 0.2 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM73801.1 - 6.5e-29 99.8 2.0 9.6e-11 41.6 0.0 4.3 3 2 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM73801.1 - 1.5e-28 98.9 0.5 1.9e-08 34.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM73801.1 - 9.7e-19 67.3 1.2 1.9e-06 28.0 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM73801.1 - 3.9e-06 27.0 0.7 0.05 13.8 0.1 4.7 3 2 0 3 3 3 1 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM73801.1 - 5.8e-06 26.6 4.9 2.8 8.4 0.0 4.6 4 2 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM73801.1 - 3.3e-05 24.0 0.3 1.7 9.0 0.0 3.7 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFM73801.1 - 5.2e-05 23.2 0.4 1.9 8.6 0.0 4.2 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM73801.1 - 0.0068 16.8 0.7 4.4 7.7 0.2 3.9 3 1 0 3 3 3 1 Immunoglobulin C1-set domain EphA2_TM PF14575.6 KFM73801.1 - 0.0098 16.8 0.7 0.026 15.4 0.7 1.8 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain C2-set PF05790.15 KFM73801.1 - 0.013 15.6 0.0 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin C2-set domain PRIMA1 PF16101.5 KFM73801.1 - 0.059 13.4 0.1 0.21 11.6 0.1 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Izumo-Ig PF16706.5 KFM73801.1 - 0.11 12.5 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain DUF4834 PF16118.5 KFM73801.1 - 0.18 12.8 0.0 0.41 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Shisa PF13908.6 KFM73801.1 - 0.22 11.7 2.2 0.82 9.9 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2076 PF09849.9 KFM73801.1 - 1.3 9.0 5.7 9.1 6.2 3.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) V-set PF07686.17 KFM73802.1 - 1.4e-07 31.7 0.0 1.5e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM73802.1 - 0.00011 22.7 0.0 0.0002 21.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM73802.1 - 0.00032 20.8 0.0 0.00053 20.1 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM73802.1 - 0.00039 20.4 0.0 0.00061 19.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM73802.1 - 0.04 14.2 0.0 0.064 13.6 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain DDE_Tnp_1_7 PF13843.6 KFM73803.1 - 9.3e-15 54.8 0.1 1e-14 54.7 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 DUF4070 PF13282.6 KFM73803.1 - 0.00087 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4070) DDE_Tnp_1_7 PF13843.6 KFM73804.1 - 7.7e-06 25.4 0.0 7.9e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Caveolin PF01146.17 KFM73806.1 - 6.5e-14 52.0 0.8 7.1e-14 51.9 0.8 1.0 1 0 0 1 1 1 1 Caveolin XOO_2897-deam PF14440.6 KFM73806.1 - 0.16 12.1 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DUF928 PF06051.12 KFM73807.1 - 0.033 14.1 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) EF-hand_6 PF13405.6 KFM73808.1 - 4.8e-10 38.6 1.4 6.9e-05 22.5 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KFM73808.1 - 2.5e-07 29.8 1.3 0.014 14.9 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFM73808.1 - 1.3e-06 28.8 2.8 3.5e-06 27.4 1.5 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM73808.1 - 0.00042 19.7 0.1 0.0077 15.7 0.0 2.8 2 0 0 2 2 2 1 EF hand FixH PF05751.11 KFM73808.1 - 0.25 11.4 0.0 0.25 11.4 0.0 1.4 2 0 0 2 2 2 0 FixH GIDA PF01134.22 KFM73809.1 - 6.1e-148 493.1 0.0 8.8e-148 492.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KFM73809.1 - 1.4e-52 178.9 1.8 2e-52 178.4 1.8 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KFM73809.1 - 1.5e-06 27.9 0.1 2e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM73809.1 - 4.5e-06 26.1 1.0 2.4e-05 23.8 0.9 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM73809.1 - 0.0021 17.2 1.9 0.0026 16.9 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KFM73809.1 - 0.0027 17.0 0.0 0.077 12.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFM73809.1 - 0.0035 16.7 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KFM73809.1 - 0.0044 17.6 0.1 0.012 16.1 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM73809.1 - 0.0079 14.9 1.6 0.022 13.5 0.2 2.3 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 KFM73809.1 - 0.12 11.9 0.1 27 4.2 0.0 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFM73809.1 - 0.16 11.0 0.1 1.2 8.1 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KFM73809.1 - 0.17 11.1 0.2 0.65 9.2 0.0 1.9 2 0 0 2 2 2 0 Thi4 family DASH_Dam1 PF08653.10 KFM73813.1 - 0.55 10.1 4.8 0.43 10.4 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 TCR PF03638.15 KFM73813.1 - 4.2 7.8 16.5 8.6 6.8 16.5 1.6 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Osmo_CC PF08946.10 KFM73813.1 - 5.9 7.2 10.7 2.3 8.5 0.1 3.4 3 0 0 3 3 3 0 Osmosensory transporter coiled coil NPV_P10 PF05531.12 KFM73813.1 - 7.9 7.0 10.1 27 5.3 3.3 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Octopine_DH PF02317.17 KFM73814.1 - 0.14 12.2 0.4 0.24 11.5 0.4 1.4 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF5082 PF16888.5 KFM73814.1 - 0.23 11.7 8.1 3.5 7.9 1.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) WD40_alt PF14077.6 KFM73814.1 - 3.1 7.7 8.0 0.33 10.9 0.5 2.6 1 1 2 3 3 3 0 Alternative WD40 repeat motif DivIC PF04977.15 KFM73814.1 - 4.3 7.2 10.6 2.5 7.9 1.5 2.9 1 1 1 2 2 2 0 Septum formation initiator HTH_Tnp_Tc3_2 PF01498.18 KFM73815.1 - 2.2e-16 59.8 2.2 3.9e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73815.1 - 7.8e-13 48.4 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73816.1 - 2.6e-12 46.8 6.3 5.6e-12 45.7 6.3 1.6 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 KFM73816.1 - 2.3e-07 30.5 0.1 3.4e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73816.1 - 0.012 15.4 1.5 0.065 13.1 0.1 2.6 3 0 0 3 3 3 0 Homeodomain-like domain Bac_DnaA_C PF08299.11 KFM73816.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix SulA PF03846.14 KFM73816.1 - 0.06 13.3 0.6 0.11 12.4 0.2 1.7 2 0 0 2 2 2 0 Cell division inhibitor SulA Peptidase_C32 PF05411.12 KFM73816.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase HTH_32 PF13565.6 KFM73816.1 - 5.9 7.6 10.2 0.18 12.4 2.0 2.5 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73817.1 - 2.1e-16 59.9 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73817.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73818.1 - 4.9e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73818.1 - 3.3e-13 49.6 0.0 5.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73818.1 - 7.4e-08 32.0 0.8 7.2e-07 28.9 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73818.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73818.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain LRR_8 PF13855.6 KFM73819.1 - 1e-26 92.4 7.4 1.1e-12 47.5 0.0 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFM73819.1 - 8e-15 54.7 9.6 2.6e-06 27.7 0.1 4.1 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) I-set PF07679.16 KFM73819.1 - 3.8e-14 52.5 0.0 7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM73819.1 - 2.8e-13 50.3 0.1 1.1e-12 48.4 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFM73819.1 - 9.9e-10 38.5 0.0 2.4e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFM73819.1 - 2.3e-08 33.4 12.7 0.76 10.6 0.0 7.1 5 1 0 5 5 5 2 Leucine Rich Repeat Ig_2 PF13895.6 KFM73819.1 - 1.2e-06 28.8 0.1 5e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain LRR_5 PF13306.6 KFM73819.1 - 4.3e-06 26.7 0.0 9.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) V-set PF07686.17 KFM73819.1 - 0.00013 22.1 0.0 0.00055 20.1 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRRCT PF01463.24 KFM73819.1 - 0.0083 16.6 0.2 0.086 13.4 0.1 2.9 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain Adeno_E3_CR1 PF02440.15 KFM73819.1 - 0.014 15.2 0.9 0.022 14.6 0.0 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 LRR_9 PF14580.6 KFM73819.1 - 0.037 13.5 1.5 0.25 10.8 1.4 1.8 1 1 1 2 2 2 0 Leucine-rich repeat Ig_6 PF18452.1 KFM73819.1 - 0.068 12.8 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain DUF1326 PF07040.11 KFM73819.1 - 0.16 12.0 0.2 0.28 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) LRR_6 PF13516.6 KFM73819.1 - 0.67 10.2 14.0 0.82 9.9 0.4 5.0 5 0 0 5 5 5 0 Leucine Rich repeat C2 PF00168.30 KFM73821.1 - 5e-08 33.2 0.0 4.2e-06 27.0 0.0 2.4 2 1 0 2 2 2 1 C2 domain G6B PF15096.6 KFM73821.1 - 0.016 15.0 0.1 0.031 14.1 0.0 1.4 1 1 0 1 1 1 0 G6B family Ndc1_Nup PF09531.10 KFM73821.1 - 0.067 11.9 1.4 0.079 11.6 1.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2062 PF09835.9 KFM73821.1 - 0.21 11.5 0.1 0.3 10.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) 2-Hacid_dh_C PF02826.19 KFM73822.1 - 1.1e-48 164.9 0.0 1.4e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFM73822.1 - 0.0077 16.4 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KFM73822.1 - 0.09 12.4 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PspC PF04024.12 KFM73823.1 - 0.13 12.0 2.8 0.18 11.7 2.8 1.2 1 0 0 1 1 1 0 PspC domain RINGv PF12906.7 KFM73826.1 - 1.8e-15 56.7 7.5 5.5e-15 55.2 7.5 1.9 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KFM73826.1 - 0.0069 16.7 13.0 0.0083 16.4 8.4 2.6 2 0 0 2 2 2 1 Ring finger domain 2-Hacid_dh_C PF02826.19 KFM73827.1 - 1.3e-58 197.3 0.0 1.8e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFM73827.1 - 2.9e-31 107.9 0.0 3.4e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFM73827.1 - 3.4e-06 27.3 0.0 6.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 KFM73827.1 - 0.0021 17.5 0.1 0.0072 15.7 0.1 1.8 2 0 0 2 2 2 1 ThiF family NAD_binding_7 PF13241.6 KFM73827.1 - 0.014 15.8 0.0 0.099 13.1 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KFM73827.1 - 0.016 15.8 0.0 0.042 14.4 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KFM73827.1 - 0.046 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Peptidase_M14 PF00246.24 KFM73828.1 - 4.7e-77 259.6 0.0 6.7e-69 232.9 0.1 2.1 1 1 1 2 2 2 2 Zinc carboxypeptidase Propep_M14 PF02244.16 KFM73828.1 - 6.8e-18 64.8 0.2 1.5e-17 63.8 0.2 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Thioredoxin_8 PF13905.6 KFM73828.1 - 0.02 15.2 0.2 0.52 10.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like VWA_N PF08399.11 KFM73829.1 - 2.8e-29 102.1 0.2 2.8e-29 102.1 0.2 2.6 3 0 0 3 3 2 1 VWA N-terminal VGCC_alpha2 PF08473.11 KFM73829.1 - 1.8e-12 46.8 0.2 5e-12 45.3 0.1 1.8 2 0 0 2 2 2 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA PF00092.28 KFM73829.1 - 1e-11 45.4 0.0 2.8e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFM73829.1 - 4.2e-11 43.4 0.1 2.8e-10 40.8 0.1 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFM73829.1 - 5.7e-11 42.6 0.0 1.5e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 KFM73829.1 - 2.7e-06 27.4 2.3 1.3e-05 25.2 0.1 2.6 3 0 0 3 3 3 1 Cache domain Apolipoprotein PF01442.18 KFM73829.1 - 0.0047 16.8 10.8 0.016 15.1 10.8 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain rve PF00665.26 KFM73829.1 - 0.0089 16.2 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain YtxH PF12732.7 KFM73829.1 - 0.023 15.2 7.9 0.54 10.8 1.5 2.7 2 0 0 2 2 2 0 YtxH-like protein Baculo_PEP_C PF04513.12 KFM73829.1 - 0.025 14.6 0.1 0.14 12.2 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 KFM73829.1 - 0.089 12.7 3.3 0.43 10.5 2.6 2.5 1 1 1 2 2 2 0 Heat shock factor binding protein 1 Phasin PF05597.11 KFM73829.1 - 0.13 12.3 14.9 0.057 13.4 3.9 2.8 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.13 KFM73829.1 - 0.39 11.3 9.8 1.9 9.2 3.3 3.1 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF883) Med9 PF07544.13 KFM73829.1 - 0.44 10.7 2.7 1.6 8.9 2.3 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4795 PF16043.5 KFM73829.1 - 0.45 10.1 10.3 0.57 9.7 4.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) ApoO PF09769.9 KFM73829.1 - 0.67 9.9 3.4 1.6 8.7 0.9 2.5 1 1 1 2 2 2 0 Apolipoprotein O FAP206 PF12018.8 KFM73829.1 - 0.71 9.3 5.2 1.8 8.0 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function ApoLp-III PF07464.11 KFM73829.1 - 0.88 9.6 12.7 5.5 7.1 12.7 2.2 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) COG2 PF06148.11 KFM73829.1 - 0.93 9.6 12.8 0.072 13.2 4.0 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2884 PF11101.8 KFM73829.1 - 0.95 8.9 11.0 0.76 9.2 8.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) DUF1664 PF07889.12 KFM73829.1 - 3.1 7.9 14.6 0.47 10.5 2.4 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DUF148 PF02520.17 KFM73829.1 - 4.8 7.3 8.7 30 4.8 1.7 2.9 1 1 1 2 2 2 0 Domain of unknown function DUF148 CdvA PF18822.1 KFM73829.1 - 9.3 6.1 15.4 0.49 10.2 1.6 3.3 3 0 0 3 3 3 0 CdvA-like coiled-coil domain FlaC_arch PF05377.11 KFM73829.1 - 10 6.6 14.5 0.29 11.5 3.8 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) VGCC_alpha2 PF08473.11 KFM73830.1 - 6e-08 31.9 1.1 6.8e-08 31.7 1.1 1.0 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA PF00092.28 KFM73831.1 - 5.4e-07 30.0 0.0 5.7e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VGCC_alpha2 PF08473.11 KFM73832.1 - 7.1e-12 44.8 0.0 7.9e-12 44.7 0.0 1.0 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd Endonuc_Holl PF10107.9 KFM73833.1 - 0.2 11.5 0.0 0.2 11.5 0.0 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DDE_Tnp_1_7 PF13843.6 KFM73835.1 - 2.1e-14 53.6 0.1 2.3e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 DUF4817 PF16087.5 KFM73837.1 - 1.3e-08 34.5 0.4 3.7e-08 33.1 0.4 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_23 PF13384.6 KFM73837.1 - 0.0003 20.5 0.2 0.0012 18.5 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.6 KFM73837.1 - 0.0008 19.2 0.0 0.0089 15.8 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73837.1 - 0.049 13.9 0.2 0.088 13.1 0.2 1.5 1 0 0 1 1 1 0 Transposase HTH_IclR PF09339.10 KFM73837.1 - 0.062 13.1 0.0 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_29 PF13551.6 KFM73837.1 - 0.069 13.2 0.4 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix SSP160 PF06933.11 KFM73837.1 - 0.24 9.6 0.1 0.31 9.2 0.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HTH_Tnp_Tc3_2 PF01498.18 KFM73838.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73838.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PBC PF03792.13 KFM73839.1 - 4.2e-20 72.3 1.1 5.5e-20 71.9 1.1 1.2 1 0 0 1 1 1 1 PBC domain Prefoldin_2 PF01920.20 KFM73841.1 - 0.0037 17.2 0.6 0.0057 16.6 0.3 1.5 2 0 0 2 2 2 1 Prefoldin subunit T6SS_TssG PF06996.11 KFM73841.1 - 0.096 11.9 0.0 0.1 11.8 0.0 1.0 1 0 0 1 1 1 0 Type VI secretion, TssG HNF-1_N PF04814.13 KFM73842.1 - 2.8e-22 80.3 7.0 9.9e-20 72.0 7.0 2.7 1 1 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 KFM73842.1 - 4.6e-07 29.6 0.9 1.8e-06 27.7 0.1 2.4 3 0 0 3 3 3 1 Homeodomain HTH_3 PF01381.22 KFM73842.1 - 0.00012 22.1 0.0 0.0036 17.3 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_37 PF13744.6 KFM73842.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Homeobox_KN PF05920.11 KFM73842.1 - 0.023 14.6 0.4 0.27 11.1 0.0 2.6 3 0 0 3 3 3 0 Homeobox KN domain HTH_31 PF13560.6 KFM73842.1 - 0.15 12.4 0.0 4.8 7.6 0.0 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain Glyco_transf_8 PF01501.20 KFM73844.1 - 1.9e-13 50.6 0.1 2.7e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KFM73844.1 - 0.0027 17.7 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Flu_B_NS1 PF02942.14 KFM73844.1 - 0.015 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) MgtE PF01769.16 KFM73846.1 - 3.1e-06 27.6 0.0 4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Divalent cation transporter MgtE PF01769.16 KFM73847.1 - 7.2e-08 32.9 0.1 7.4e-08 32.8 0.1 1.0 1 0 0 1 1 1 1 Divalent cation transporter MgtE PF01769.16 KFM73848.1 - 0.00054 20.3 2.3 0.00059 20.2 2.3 1.0 1 0 0 1 1 1 1 Divalent cation transporter DUF4598 PF15370.6 KFM73850.1 - 1e-06 29.2 0.6 1e-06 29.2 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) EF-G-binding_N PF07299.11 KFM73850.1 - 0.0016 18.9 0.3 0.0021 18.5 0.3 1.4 1 1 0 1 1 1 1 Elongation factor G-binding protein, N-terminal Zona_pellucida PF00100.23 KFM73851.1 - 0.00036 20.4 4.9 0.00036 20.4 4.9 1.4 2 0 0 2 2 2 1 Zona pellucida-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73853.1 - 4.5e-14 52.4 0.9 8.8e-14 51.5 0.9 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73853.1 - 1.4e-12 47.6 0.0 2.4e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM73853.1 - 0.00046 20.8 5.4 0.001 19.6 1.7 2.5 2 0 0 2 2 2 1 Homeodomain-like domain Gly_rich PF12810.7 KFM73853.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycine rich protein HMG_box PF00505.19 KFM73854.1 - 2.1e-27 95.3 3.4 3.4e-27 94.7 3.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM73854.1 - 4.6e-10 39.9 1.5 8.4e-10 39.1 1.5 1.4 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 KFM73855.1 - 3.2e-12 46.7 0.1 3.5e-12 46.6 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM73855.1 - 8.7e-10 38.6 0.1 1.1e-09 38.3 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 KFM73855.1 - 0.0054 16.5 0.1 0.0066 16.2 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) C2-set_2 PF08205.12 KFM73856.1 - 1.6e-06 28.1 0.1 2.3e-06 27.6 0.1 1.3 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM73856.1 - 1.2e-05 25.8 0.3 0.00017 22.1 0.3 2.1 1 1 1 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM73856.1 - 1.6e-05 25.2 0.2 9.2e-05 22.7 0.2 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Transposase_1 PF01359.18 KFM73857.1 - 1.1e-14 54.0 0.3 2.5e-14 52.9 0.1 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM73857.1 - 7.9e-14 51.5 0.2 1.6e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_50 PF18024.1 KFM73857.1 - 0.00024 20.6 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM73857.1 - 0.00038 20.6 0.0 0.00077 19.7 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_11 PF08279.12 KFM73857.1 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_28 PF13518.6 KFM73857.1 - 0.026 14.6 0.3 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 KFM73857.1 - 0.043 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain DDE_Tnp_1_7 PF13843.6 KFM73858.1 - 3e-77 260.3 0.0 4e-77 259.9 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM73858.1 - 1.2e-07 31.6 0.0 3.7e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Transposase DDE domain Peptidase_C71 PF12386.8 KFM73858.1 - 0.045 13.4 0.2 0.18 11.4 0.2 1.9 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei RVT_1 PF00078.27 KFM73861.1 - 1.9e-28 99.5 0.1 2.3e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.18 KFM73862.1 - 4.3e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73862.1 - 8.8e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73862.1 - 2.7e-07 30.2 1.1 6.6e-07 29.0 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73862.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73862.1 - 1.7 9.3 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM73863.1 - 4.2e-11 42.8 0.0 4.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease MULE PF10551.9 KFM73864.1 - 2.1e-14 53.7 4.8 7e-14 52.0 0.4 3.2 3 0 0 3 3 3 1 MULE transposase domain zf-C2H2_4 PF13894.6 KFM73864.1 - 0.0056 17.4 5.4 0.055 14.3 0.2 5.8 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM73864.1 - 0.11 12.4 4.6 0.37 10.7 0.0 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Hydrolase_3 PF08282.12 KFM73864.1 - 4.5 6.9 7.2 3.2 7.4 0.6 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Enkurin PF13864.6 KFM73864.1 - 9 6.8 10.2 2.5 8.6 1.9 3.8 3 1 1 4 4 4 0 Calmodulin-binding ERM PF00769.19 KFM73866.1 - 3.8e-55 187.4 42.6 3.8e-55 187.4 42.6 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 KFM73866.1 - 4.8e-26 91.0 1.0 7e-26 90.5 0.1 1.8 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFM73866.1 - 7.2e-25 87.7 0.4 7.2e-25 87.7 0.4 3.4 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFM73866.1 - 1.6e-12 47.1 2.8 1.3e-11 44.2 0.2 3.3 3 0 0 3 3 3 1 FERM N-terminal domain ACBP PF00887.19 KFM73866.1 - 0.0048 17.1 1.6 0.0084 16.3 0.1 2.2 2 0 0 2 2 2 1 Acyl CoA binding protein Ala_racemase_N PF01168.20 KFM73868.1 - 1.9e-13 50.6 0.0 2.1e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain 2-Hacid_dh PF00389.30 KFM73868.1 - 0.099 12.3 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Lipocalin_2 PF08212.12 KFM73870.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.5 1 1 1 2 2 2 0 Lipocalin-like domain InaF-motif PF15018.6 KFM73871.1 - 1.5e-18 66.3 4.0 2e-18 65.9 4.0 1.2 1 0 0 1 1 1 1 TRP-interacting helix SDF PF00375.18 KFM73871.1 - 0.078 12.0 0.0 0.095 11.7 0.0 1.0 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family SOCS_box PF07525.16 KFM73872.1 - 0.00047 20.5 2.7 0.0012 19.1 2.7 1.7 1 0 0 1 1 1 1 SOCS box Herpes_UL1 PF05259.11 KFM73872.1 - 0.19 11.8 1.2 0.94 9.6 0.3 2.2 1 1 1 2 2 2 0 Herpesvirus glycoprotein L Sulfatase PF00884.23 KFM73873.1 - 1e-10 41.5 0.0 1.2e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Sulfatase PF00884.23 KFM73874.1 - 2.1e-14 53.7 0.1 2.3e-14 53.5 0.1 1.0 1 0 0 1 1 1 1 Sulfatase Pro_isomerase PF00160.21 KFM73876.1 - 1.1e-44 152.5 0.1 1.6e-44 152.0 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KFM73877.1 - 1.2e-06 28.2 0.0 1.3e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM73877.1 - 0.014 15.5 0.0 0.015 15.4 0.0 1.0 1 0 0 1 1 1 0 RNA recognition motif RVT_1 PF00078.27 KFM73878.1 - 6.6e-23 81.4 0.0 2e-22 79.8 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM73878.1 - 1.3e-17 64.1 0.0 3e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM73878.1 - 2.2e-16 59.7 0.5 6.5e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain DDE_3 PF13358.6 KFM73878.1 - 3.5e-15 56.0 0.0 2.1e-10 40.5 0.0 3.1 3 0 0 3 3 3 2 DDE superfamily endonuclease zf-H2C2 PF09337.10 KFM73878.1 - 0.0011 19.1 0.0 0.0034 17.6 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM73879.1 - 1.3e-05 25.3 0.2 2.1e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Transposase NDUF_B5 PF09781.9 KFM73880.1 - 2.1e-53 180.7 1.2 2.5e-53 180.5 1.2 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Photo_RC PF00124.19 KFM73880.1 - 0.0034 16.7 0.0 0.004 16.4 0.0 1.1 1 0 0 1 1 1 1 Photosynthetic reaction centre protein GMP_PDE_delta PF05351.11 KFM73881.1 - 7.5e-46 156.0 0.0 9.7e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit ANF_receptor PF01094.28 KFM73883.1 - 0.018 14.1 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region ANF_receptor PF01094.28 KFM73884.1 - 0.0054 15.9 0.2 0.0057 15.8 0.2 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region DUF3235 PF11574.8 KFM73885.1 - 6.6 7.7 9.0 79 4.2 1.3 4.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3235) Ank_2 PF12796.7 KFM73886.1 - 6.6e-33 113.2 2.8 4.1e-15 56.1 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM73886.1 - 3.5e-29 100.5 9.5 9.8e-08 32.1 0.0 5.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM73886.1 - 9.1e-29 99.5 4.4 1.3e-09 38.4 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM73886.1 - 1.9e-26 89.2 4.7 1.8e-05 24.8 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KFM73886.1 - 3.9e-26 90.3 5.3 6.6e-05 23.2 0.1 6.2 6 0 0 6 6 6 5 Ankyrin repeat Rootletin PF15035.6 KFM73886.1 - 0.24 11.4 1.2 0.6 10.1 0.1 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SET PF00856.28 KFM73887.1 - 2.9e-25 89.6 0.2 9.8e-25 87.9 0.1 1.9 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 KFM73887.1 - 9.1e-18 64.9 16.1 2.5e-17 63.5 12.3 2.2 2 0 0 2 2 2 1 Pre-SET motif RabGAP-TBC PF00566.18 KFM73888.1 - 1.8e-53 181.4 0.9 1.8e-53 181.4 0.9 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF287 PF03384.14 KFM73897.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 FSA_C PF10479.9 KFM73899.1 - 7.1e-101 338.5 0.3 7.1e-101 338.5 0.3 1.6 2 0 0 2 2 2 1 Fragile site-associated protein C-terminus FSA_C PF10479.9 KFM73900.1 - 3.8e-137 458.4 1.9 2e-96 323.7 0.1 2.0 1 1 1 2 2 2 2 Fragile site-associated protein C-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM73901.1 - 4.2e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73901.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73901.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73901.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73901.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DRY_EERY PF09750.9 KFM73903.1 - 0.0062 16.8 1.1 0.007 16.6 1.1 1.1 1 0 0 1 1 1 1 Alternative splicing regulator Ank_2 PF12796.7 KFM73904.1 - 4.6e-09 36.7 1.0 0.0017 18.9 0.5 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) TRP_2 PF08344.11 KFM73904.1 - 2.2e-07 31.0 4.2 4.7e-07 29.9 4.2 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_3 PF13606.6 KFM73904.1 - 5.1e-07 29.5 1.1 0.029 14.9 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KFM73904.1 - 2.2e-06 28.1 0.3 0.038 14.6 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM73904.1 - 1.4e-05 25.3 0.0 0.058 13.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM73904.1 - 0.00048 20.4 0.1 0.28 11.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 KFM73904.1 - 0.022 14.7 4.4 0.072 13.1 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) Ion_trans PF00520.31 KFM73905.1 - 2.5e-20 72.7 19.3 3.8e-20 72.1 19.3 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 KFM73905.1 - 1.1e-19 70.4 1.8 2.6e-19 69.2 1.8 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 KFM73905.1 - 3.8e-07 30.6 0.1 0.07 13.7 0.1 3.6 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM73905.1 - 2.8e-06 27.8 0.0 0.011 16.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM73905.1 - 0.021 15.3 0.1 1.9 9.3 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KFM73905.1 - 0.034 14.5 0.6 0.49 10.8 0.1 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) LRRFIP PF09738.9 KFM73905.1 - 0.37 10.2 4.6 1.3 8.5 0.5 2.1 2 0 0 2 2 2 0 LRRFIP family DM4_12 PF07841.13 KFM73906.1 - 1.4e-08 35.3 0.1 3.8e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 DM4/DM12 family Lin-8 PF03353.15 KFM73906.1 - 0.014 15.0 4.8 0.02 14.5 4.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 KFM73906.1 - 0.03 13.1 0.9 0.043 12.6 0.9 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KFM73906.1 - 0.037 13.3 0.7 0.048 12.9 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 KFM73906.1 - 0.19 9.8 1.2 0.2 9.8 1.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Trypan_PARP PF05887.11 KFM73906.1 - 0.83 9.6 14.0 1.9 8.5 14.0 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Asp-B-Hydro_N PF05279.11 KFM73906.1 - 9.7 6.2 12.3 16 5.4 12.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spidroin_N PF16763.5 KFM73910.1 - 4.9e-31 107.3 3.6 8.9e-31 106.5 3.6 1.4 1 0 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term Spaetzle PF16077.5 KFM73911.1 - 0.0059 17.1 0.4 0.0098 16.4 0.4 1.4 1 0 0 1 1 1 1 Spaetzle NGF PF00243.18 KFM73911.1 - 0.025 14.8 0.3 0.049 13.9 0.3 1.4 1 0 0 1 1 1 0 Nerve growth factor family zf-H2C2_2 PF13465.6 KFM73914.1 - 1e-15 57.3 10.8 4e-09 36.5 1.5 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73914.1 - 3.1e-12 46.2 25.6 3.6e-05 24.0 4.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73914.1 - 2.6e-09 37.1 23.6 0.0064 17.2 3.2 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM73914.1 - 8.5e-07 28.6 15.1 1.7e-06 27.7 1.2 3.3 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM73914.1 - 0.00013 22.2 10.0 0.0002 21.6 2.6 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFM73914.1 - 0.002 18.5 17.9 0.022 15.1 2.5 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KFM73914.1 - 0.041 13.8 6.5 0.35 10.8 0.5 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger HypA PF01155.19 KFM73914.1 - 0.056 13.5 4.5 0.13 12.3 2.8 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-UBR PF02207.20 KFM73914.1 - 0.071 13.3 9.6 0.13 12.5 9.6 1.6 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_11 PF16622.5 KFM73914.1 - 0.08 12.7 13.0 0.41 10.5 1.0 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type C1_1 PF00130.22 KFM73914.1 - 0.1 12.5 12.1 0.13 12.2 0.9 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KFM73914.1 - 0.12 12.5 0.5 0.12 12.5 0.5 2.9 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 KFM73914.1 - 0.61 10.6 13.3 3.6 8.1 1.9 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zf_RING PF16744.5 KFM73914.1 - 0.68 10.1 7.9 6.7 6.9 2.7 2.8 1 1 1 2 2 2 0 KIAA1045 RING finger FYVE PF01363.21 KFM73914.1 - 0.68 10.1 9.5 4.3 7.6 0.9 2.2 1 1 0 2 2 2 0 FYVE zinc finger zf-C2H2_jaz PF12171.8 KFM73914.1 - 0.7 10.2 18.2 0.32 11.3 1.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TFIIS_C PF01096.18 KFM73914.1 - 1.1 9.2 0.1 1.1 9.2 0.1 3.0 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 KFM73914.1 - 1.2 9.2 14.0 1.1 9.3 6.9 2.5 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_15 PF17032.5 KFM73914.1 - 4.2 8.2 12.7 37 5.1 12.7 2.0 1 1 0 1 1 1 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 KFM73914.1 - 7.3 6.3 16.3 1.9 8.2 1.2 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DDE_3 PF13358.6 KFM73915.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 1 1 2 2 2 0 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM73916.1 - 7e-17 61.0 22.5 5.1e-08 33.0 4.6 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM73916.1 - 1.4e-11 44.2 22.2 4.7e-05 23.9 1.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM73916.1 - 1e-09 38.3 24.2 1.3e-06 28.5 1.7 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM73916.1 - 3e-06 26.9 4.9 3e-06 26.9 4.9 3.2 3 1 0 3 3 2 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFM73916.1 - 5.6e-06 26.6 0.6 5.6e-06 26.6 0.6 3.0 4 0 0 4 4 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM73916.1 - 0.00036 20.7 9.6 0.0005 20.3 1.5 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFM73916.1 - 0.00041 20.6 0.1 0.00041 20.6 0.1 3.7 3 1 0 3 3 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KFM73916.1 - 0.0017 18.3 15.5 0.061 13.4 1.7 3.1 1 1 2 3 3 3 2 BED zinc finger zf-C2H2_6 PF13912.6 KFM73916.1 - 0.0026 17.7 0.4 0.0026 17.7 0.4 4.0 3 2 0 3 3 3 1 C2H2-type zinc finger A2L_zn_ribbon PF08792.10 KFM73916.1 - 0.028 14.2 8.5 1.6 8.5 0.3 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-C2HE PF16278.5 KFM73916.1 - 0.034 14.6 0.6 0.034 14.6 0.6 2.7 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Sec23_Sec24 PF04810.15 KFM73916.1 - 0.041 13.9 4.9 4.7 7.3 1.9 2.6 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf_C2H2_ZHX PF18387.1 KFM73916.1 - 0.051 13.2 14.0 0.057 13.1 0.3 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3268 PF11672.8 KFM73916.1 - 0.092 13.1 4.1 0.8 10.0 0.6 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain zf-CHCC PF10276.9 KFM73916.1 - 0.092 12.8 9.6 0.3 11.2 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_2 PF12756.7 KFM73916.1 - 0.11 12.9 0.9 0.11 12.9 0.9 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) HypA PF01155.19 KFM73916.1 - 0.24 11.4 2.2 0.67 10.0 2.2 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-MYST PF17772.1 KFM73916.1 - 0.27 10.9 0.2 0.27 10.9 0.2 3.0 1 1 2 3 3 3 0 MYST family zinc finger domain zf-AN1 PF01428.16 KFM73916.1 - 0.29 11.3 8.9 1.6 8.9 0.2 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger zf-nanos PF05741.13 KFM73916.1 - 0.3 11.4 9.4 2.1 8.6 4.1 3.1 2 1 0 2 2 2 0 Nanos RNA binding domain YyzF PF14116.6 KFM73916.1 - 0.37 10.9 3.8 3.5 7.7 0.1 2.8 3 0 0 3 3 3 0 YyzF-like protein Zf_RING PF16744.5 KFM73916.1 - 0.37 10.9 7.0 3.8 7.7 0.3 2.6 1 1 1 2 2 2 0 KIAA1045 RING finger zf_UBZ PF18439.1 KFM73916.1 - 0.48 10.1 7.6 1.7 8.3 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF2225 PF09986.9 KFM73916.1 - 0.62 9.8 5.1 0.14 11.9 0.9 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_15 PF17032.5 KFM73916.1 - 0.66 10.8 7.7 3.2 8.6 7.7 1.9 1 1 1 2 2 2 0 zinc-ribbon family Nudix_N_2 PF14803.6 KFM73916.1 - 0.78 9.7 6.6 3.3 7.7 0.0 3.6 4 1 0 4 4 4 0 Nudix N-terminal zinc-ribbons_6 PF07191.12 KFM73916.1 - 0.97 9.5 8.6 1e+02 3.0 7.6 2.9 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_3rep PF18868.1 KFM73916.1 - 1.1 9.9 6.5 2 9.1 4.6 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Cas_CXXC_CXXC PF09706.10 KFM73916.1 - 1.4 9.2 9.8 2.6 8.3 0.3 3.0 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-HIT PF04438.16 KFM73916.1 - 1.5 8.8 14.1 5.7 6.9 3.2 3.2 3 0 0 3 3 3 0 HIT zinc finger Zn-ribbon_8 PF09723.10 KFM73916.1 - 2.5 8.3 12.2 4.3 7.5 6.4 2.9 1 1 2 3 3 3 0 Zinc ribbon domain PyrI_C PF02748.15 KFM73916.1 - 3.2 7.7 15.1 0.96 9.4 1.8 3.1 1 1 2 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C4_ClpX PF06689.13 KFM73916.1 - 5.9 6.9 10.6 5.8 6.9 0.3 2.9 2 1 0 2 2 2 0 ClpX C4-type zinc finger zf-H2C2_2 PF13465.6 KFM73917.1 - 9.3e-21 73.3 20.8 1.9e-09 37.5 1.3 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73917.1 - 2e-20 72.0 20.7 1.9e-07 31.2 0.9 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73917.1 - 1e-15 57.0 17.6 1.5e-05 25.4 0.6 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM73917.1 - 7.9e-11 42.0 18.4 0.00012 22.3 0.9 3.5 4 0 0 4 4 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM73917.1 - 5.3e-08 32.9 16.4 0.004 17.4 1.3 4.1 3 1 1 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM73917.1 - 4.4e-07 29.5 4.4 0.0056 16.4 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-BED PF02892.15 KFM73917.1 - 1.1e-05 25.4 16.9 0.0064 16.5 1.7 3.2 1 1 2 3 3 3 3 BED zinc finger zf-Di19 PF05605.12 KFM73917.1 - 5.7e-05 23.3 6.6 0.0026 18.0 1.0 2.2 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Zf_RING PF16744.5 KFM73917.1 - 8.1e-05 22.7 7.0 0.61 10.2 0.2 3.1 1 1 2 3 3 3 2 KIAA1045 RING finger C1_2 PF03107.16 KFM73917.1 - 9.4e-05 22.6 9.3 0.21 11.9 0.3 3.1 1 1 2 3 3 3 3 C1 domain zf-C2H2_11 PF16622.5 KFM73917.1 - 0.00033 20.3 11.8 0.54 10.1 2.7 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type BolA PF01722.18 KFM73917.1 - 0.0004 20.6 0.6 0.26 11.6 0.3 2.5 1 1 2 3 3 3 1 BolA-like protein zf-C2H2_3rep PF18868.1 KFM73917.1 - 0.00043 20.9 7.5 0.51 11.0 0.1 3.0 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats GAGA PF09237.11 KFM73917.1 - 0.00047 19.9 4.3 0.012 15.4 0.2 2.9 1 1 2 3 3 3 1 GAGA factor zf-C2H2_2 PF12756.7 KFM73917.1 - 0.00048 20.4 9.8 0.26 11.6 0.2 3.0 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM73917.1 - 0.00069 20.3 9.9 0.01 16.5 1.3 2.0 1 1 1 2 2 2 2 zinc-ribbon family zf-C2H2_6 PF13912.6 KFM73917.1 - 0.0013 18.7 13.6 0.53 10.3 1.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger FYVE PF01363.21 KFM73917.1 - 0.004 17.3 11.9 0.088 13.0 11.9 2.4 1 1 0 1 1 1 1 FYVE zinc finger HNH_5 PF14279.6 KFM73917.1 - 0.0041 17.0 6.4 0.17 11.8 1.6 3.1 2 1 0 2 2 2 1 HNH endonuclease zf-C2HC_2 PF13913.6 KFM73917.1 - 0.0044 16.9 11.6 2.3 8.2 0.2 3.5 3 1 0 3 3 3 1 zinc-finger of a C2HC-type Prok-RING_1 PF14446.6 KFM73917.1 - 0.012 15.6 5.2 7.9 6.5 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Cript PF10235.9 KFM73917.1 - 0.017 15.7 9.0 0.077 13.6 2.6 2.3 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Zn-C2H2_12 PF18112.1 KFM73917.1 - 0.018 15.5 4.0 6 7.4 0.3 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 KFM73917.1 - 0.018 14.6 6.7 1 9.0 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C3HC4 PF00097.25 KFM73917.1 - 0.018 14.9 3.1 22 5.0 0.0 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_2 PF13696.6 KFM73917.1 - 0.019 14.8 10.5 0.35 10.7 1.3 3.5 3 0 0 3 3 3 0 Zinc knuckle C1_4 PF07975.12 KFM73917.1 - 0.021 15.1 7.5 0.45 10.8 1.2 2.2 1 1 0 2 2 2 0 TFIIH C1-like domain DUF2256 PF10013.9 KFM73917.1 - 0.022 14.8 5.6 2.8 8.1 0.2 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 KFM73917.1 - 0.031 14.7 13.7 0.27 11.7 0.6 2.9 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Elf1 PF05129.13 KFM73917.1 - 0.034 14.2 9.5 0.17 11.9 3.0 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.19 KFM73917.1 - 0.047 13.7 5.6 0.77 9.8 5.6 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2175 PF09943.9 KFM73917.1 - 0.051 13.9 3.5 26 5.2 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-AN1 PF01428.16 KFM73917.1 - 0.054 13.7 12.7 5 7.4 0.5 3.2 1 1 2 3 3 3 0 AN1-like Zinc finger zf-TRAF PF02176.18 KFM73917.1 - 0.055 14.2 2.1 0.055 14.2 2.1 2.1 1 1 0 2 2 2 0 TRAF-type zinc finger C1_1 PF00130.22 KFM73917.1 - 0.059 13.3 8.5 0.64 10.0 1.6 2.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KFM73917.1 - 0.064 13.4 4.4 0.2 11.8 0.6 2.1 1 1 1 2 2 2 0 PHD-finger PyrI_C PF02748.15 KFM73917.1 - 0.086 12.8 9.9 2.8 7.9 0.1 3.1 1 1 2 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-LYAR PF08790.11 KFM73917.1 - 0.092 12.7 11.6 0.44 10.5 0.1 3.4 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger zf-FCS PF06467.14 KFM73917.1 - 0.098 12.6 9.3 2.1 8.3 0.2 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DZR PF12773.7 KFM73917.1 - 0.13 12.3 6.9 3.4 7.8 6.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon Sprouty PF05210.13 KFM73917.1 - 0.14 12.5 4.1 0.25 11.8 4.1 1.5 1 1 0 1 1 1 0 Sprouty protein (Spry) zf-Dof PF02701.15 KFM73917.1 - 0.15 12.2 9.8 5.3 7.3 0.3 3.1 1 1 2 3 3 3 0 Dof domain, zinc finger Sgf11 PF08209.11 KFM73917.1 - 0.17 11.5 6.9 3.6 7.2 0.2 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zinc-ribbons_6 PF07191.12 KFM73917.1 - 0.18 11.8 8.8 1.4 9.0 2.7 2.4 1 1 2 3 3 3 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KFM73917.1 - 0.18 12.0 9.1 1.3 9.1 3.0 2.9 1 1 1 2 2 2 0 Zinc ribbon domain LIM PF00412.22 KFM73917.1 - 0.18 12.0 10.9 1.2 9.4 0.9 3.0 1 1 1 2 2 2 0 LIM domain Actin_micro PF17003.5 KFM73917.1 - 0.22 10.7 9.8 2.4 7.3 5.7 2.7 1 1 1 2 2 2 0 Putative actin-like family zf-trcl PF13451.6 KFM73917.1 - 0.23 11.4 6.7 10 6.1 0.4 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain DUF2225 PF09986.9 KFM73917.1 - 0.25 11.0 9.5 2.1 8.0 2.3 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF629 PF04780.12 KFM73917.1 - 0.34 9.4 10.0 1.1 7.6 0.6 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF629) CpXC PF14353.6 KFM73917.1 - 0.34 10.9 8.2 1.4 9.0 0.3 2.8 1 1 2 3 3 3 0 CpXC protein zf-HYPF PF07503.12 KFM73917.1 - 0.37 10.6 6.4 9.3 6.1 0.1 2.8 2 1 0 2 2 2 0 HypF finger Rpr2 PF04032.16 KFM73917.1 - 0.47 10.8 7.0 2.9 8.2 7.0 2.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-nanos PF05741.13 KFM73917.1 - 0.49 10.7 8.9 31 4.9 0.1 3.2 2 1 0 2 2 2 0 Nanos RNA binding domain HNH PF01844.23 KFM73917.1 - 0.51 10.6 6.9 15 5.8 0.2 3.1 3 0 0 3 3 3 0 HNH endonuclease Rubredoxin PF00301.20 KFM73917.1 - 0.57 10.2 4.4 7 6.8 0.4 3.0 3 0 0 3 3 3 0 Rubredoxin zf-met2 PF12907.7 KFM73917.1 - 0.58 10.3 10.2 9.5 6.5 0.5 3.3 3 0 0 3 3 3 0 Zinc-binding zf-MYST PF17772.1 KFM73917.1 - 0.6 9.8 9.5 1.1 8.9 1.0 3.1 2 1 2 4 4 4 0 MYST family zinc finger domain DUF3449 PF11931.8 KFM73917.1 - 0.68 9.7 12.1 1.8 8.3 0.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3449) Zn_ribbon_SprT PF17283.2 KFM73917.1 - 0.71 9.8 12.6 5.9 6.9 0.8 3.0 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Zn_ribbon_recom PF13408.6 KFM73917.1 - 0.72 10.4 7.4 6.9 7.3 3.0 2.9 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain FYDLN_acid PF09538.10 KFM73917.1 - 0.9 10.2 2.9 11 6.8 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) TRAF6_Z2 PF18048.1 KFM73917.1 - 1.3 9.1 7.6 6.7 6.9 1.2 3.0 2 1 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Desulfoferrod_N PF06397.12 KFM73917.1 - 1.4 8.6 6.8 13 5.6 0.4 3.1 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf_C2H2_ZHX PF18387.1 KFM73917.1 - 1.6 8.5 7.0 3.1 7.5 0.6 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain UBZ_FAAP20 PF15750.5 KFM73917.1 - 3.1 7.8 5.1 19 5.3 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Vps39_2 PF10367.9 KFM73917.1 - 4.9 7.6 8.1 8.5 6.9 0.7 2.9 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 TFIIS_C PF01096.18 KFM73917.1 - 7.2 6.6 10.0 19 5.2 0.3 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Tnp_zf-ribbon_2 PF13842.6 KFM73917.1 - 9 7.2 10.6 15 6.5 0.4 3.2 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon DUF4764 PF15961.5 KFM73917.1 - 9.9 4.7 8.7 0.81 8.3 3.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) HTH_Tnp_Tc3_2 PF01498.18 KFM73918.1 - 4.2e-16 58.9 3.5 5.8e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73918.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73918.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73918.1 - 0.0027 17.5 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73918.1 - 2.4 8.8 15.6 0.12 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73919.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73919.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73919.1 - 1.5e-07 31.1 1.2 6.7e-07 29.0 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73919.1 - 0.0025 17.6 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73919.1 - 0.027 14.6 0.4 0.086 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM73919.1 - 2.1 9.0 15.6 0.12 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM73920.1 - 2.2e-16 59.8 2.2 4.7e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73920.1 - 9.7e-14 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PND PF17949.1 KFM73922.1 - 4.9e-26 91.4 0.0 6.4e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 FANCM pseudonuclease domain HHH_2 PF12826.7 KFM73922.1 - 8.5e-06 25.8 0.2 3.7e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 KFM73922.1 - 0.015 15.1 0.2 2 8.4 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KFM73922.1 - 0.029 15.0 0.2 0.046 14.3 0.2 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain TPR_1 PF00515.28 KFM73923.1 - 1.5e-06 27.8 12.3 0.0017 18.1 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM73923.1 - 3e-05 23.8 14.8 0.0022 18.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM73923.1 - 0.0002 21.5 4.0 0.34 11.4 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM73923.1 - 0.00056 19.9 14.1 0.061 13.6 0.1 5.2 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM73923.1 - 0.00073 19.2 0.9 0.012 15.2 0.0 2.8 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 KFM73923.1 - 0.0049 17.3 0.2 0.091 13.3 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM73923.1 - 0.076 13.9 0.8 15 6.7 0.0 3.4 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM73923.1 - 0.23 11.4 4.3 20 5.2 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM73923.1 - 1 9.5 5.3 13 6.0 0.5 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KFM73923.1 - 1 9.7 10.2 0.81 10.0 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM73923.1 - 1.4 9.1 5.5 17 5.7 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM73927.1 - 0.012 15.4 0.3 0.17 11.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM73927.1 - 0.051 13.7 1.5 0.41 10.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat STAT6_C PF14596.6 KFM73927.1 - 0.086 12.8 2.4 0.24 11.4 0.0 2.5 2 0 0 2 2 2 0 STAT6 C-terminal TPR_9 PF13371.6 KFM73927.1 - 0.12 12.6 0.0 0.63 10.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN1_RPN2_N PF17781.1 KFM73928.1 - 2e-120 401.9 2.3 2e-120 401.9 2.3 1.8 3 0 0 3 3 3 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 KFM73928.1 - 4e-27 93.2 26.7 7.2e-07 29.3 0.1 9.1 9 0 0 9 9 9 5 Proteasome/cyclosome repeat RPN1_C PF18051.1 KFM73928.1 - 4.9e-23 80.9 0.5 9.5e-23 80.0 0.5 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 KFM73928.1 - 2.2e-05 24.8 0.2 0.19 12.1 0.1 3.8 2 1 1 3 3 3 2 HEAT repeats GP67 PF17634.2 KFM73928.1 - 0.0044 17.4 1.9 0.0044 17.4 1.9 2.5 2 0 0 2 2 2 1 Gene product 67 THAP PF05485.12 KFM73928.1 - 0.11 13.5 0.3 0.27 12.2 0.3 1.6 1 0 0 1 1 1 0 THAP domain PCRF PF03462.18 KFM73929.1 - 6.6e-50 169.7 0.2 2e-49 168.1 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KFM73929.1 - 2.8e-36 124.0 2.1 2.8e-36 124.0 2.1 2.0 3 0 0 3 3 3 1 RF-1 domain rRNA_proc-arch PF13234.6 KFM73930.1 - 1.7e-85 287.3 1.9 3.1e-85 286.4 1.9 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KFM73930.1 - 1.9e-57 193.5 0.4 4.7e-57 192.2 0.4 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KFM73930.1 - 1.4e-18 67.3 0.1 9.7e-18 64.5 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM73930.1 - 8.5e-06 26.1 0.0 5.5e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ATPase_2 PF01637.18 KFM73930.1 - 0.022 14.7 0.1 0.099 12.5 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KFM73930.1 - 0.041 14.2 0.0 0.38 11.0 0.0 2.7 2 1 1 3 3 3 0 AAA domain Transcrip_act PF04949.13 KFM73931.1 - 2e-08 34.3 17.6 4.6e-08 33.1 17.6 1.6 1 0 0 1 1 1 1 Transcriptional activator DUF4417 PF14386.6 KFM73931.1 - 0.061 12.9 0.0 4.2 6.9 0.0 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4417) DUF2533 PF10752.9 KFM73931.1 - 0.064 13.7 0.6 0.064 13.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Mid2 PF04478.12 KFM73932.1 - 0.073 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Histone PF00125.24 KFM73933.1 - 2.3e-18 66.8 0.0 2.8e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFM73933.1 - 1.6e-13 50.1 0.9 7.6e-13 48.0 0.6 2.1 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFM73933.1 - 0.015 15.6 0.1 0.026 14.8 0.0 1.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hexapep PF00132.24 KFM73934.1 - 4.3e-09 35.7 10.0 2.8e-07 30.0 1.0 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KFM73934.1 - 9.4e-08 31.9 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KFM73934.1 - 0.00097 18.8 0.9 0.018 14.8 0.5 3.0 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFM73934.1 - 0.057 11.5 0.1 0.085 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) ABC_tran PF00005.27 KFM73936.1 - 3.2e-36 124.9 0.0 5.2e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KFM73936.1 - 2.1e-22 80.1 7.2 2.8e-22 79.7 7.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KFM73936.1 - 1.7e-08 34.2 0.2 1.5e-05 24.5 0.0 2.5 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain DEAD PF00270.29 KFM73936.1 - 6.5e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_5 PF07728.14 KFM73936.1 - 0.00015 21.7 0.1 0.0047 16.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM73936.1 - 0.0006 20.1 0.0 0.024 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KFM73936.1 - 0.0039 17.2 0.2 0.43 10.6 0.0 3.4 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KFM73936.1 - 0.0049 17.3 0.2 0.017 15.5 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KFM73936.1 - 0.0082 15.7 0.0 0.038 13.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFM73936.1 - 0.0092 16.5 0.0 0.026 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFM73936.1 - 0.01 16.2 0.2 0.14 12.6 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KFM73936.1 - 0.011 15.5 0.1 0.033 13.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KFM73936.1 - 0.012 15.5 0.1 0.036 13.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFM73936.1 - 0.017 15.0 0.1 0.045 13.7 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase APS_kinase PF01583.20 KFM73936.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 KFM73936.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFM73936.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KFM73936.1 - 0.029 14.9 0.2 0.092 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KFM73936.1 - 0.032 13.9 0.1 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase SbcCD_C PF13558.6 KFM73936.1 - 0.039 14.2 0.2 0.78 10.0 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KFM73936.1 - 0.041 14.0 0.1 0.092 12.8 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_30 PF13604.6 KFM73936.1 - 0.042 13.6 0.0 0.09 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFM73936.1 - 0.054 13.2 0.1 0.96 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KFM73936.1 - 0.086 12.9 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Sigma54_activat PF00158.26 KFM73936.1 - 0.094 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KFM73936.1 - 0.14 12.2 0.5 3 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain VIT1 PF01988.19 KFM73936.1 - 2 8.2 5.1 1.1 9.1 0.6 2.2 2 0 0 2 2 2 0 VIT family Exo_endo_phos_2 PF14529.6 KFM73937.1 - 2.1e-17 63.1 0.4 4.6e-17 62.0 0.1 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM73937.1 - 0.041 13.4 0.3 0.069 12.6 0.3 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PHD PF00628.29 KFM73938.1 - 1.1e-05 25.2 15.8 1.1e-05 25.2 15.8 2.5 2 0 0 2 2 2 1 PHD-finger Tudor-knot PF11717.8 KFM73938.1 - 0.00011 22.0 2.2 0.0048 16.8 0.7 3.3 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 KFM73938.1 - 0.00042 19.9 0.1 0.0016 18.1 0.1 2.1 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 KFM73938.1 - 0.0021 18.1 0.1 0.0072 16.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) MBT PF02820.18 KFM73938.1 - 0.016 15.5 0.0 0.061 13.7 0.0 2.0 1 0 0 1 1 1 0 mbt repeat TraI_2B PF18340.1 KFM73938.1 - 0.045 13.8 1.1 0.19 11.8 0.1 2.5 2 0 0 2 2 2 0 DNA relaxase TraI 2B/2B-like domain Peptidase_S24 PF00717.23 KFM73938.1 - 0.061 13.3 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Peptidase S24-like NitrOD1 PF18549.1 KFM73938.1 - 2.2 8.3 5.4 7 6.7 0.2 3.3 4 0 0 4 4 4 0 Nitrosopumilus output domain 1 Agenet PF05641.12 KFM73938.1 - 3.4 8.2 8.6 6 7.4 0.4 4.3 3 0 0 3 3 3 0 Agenet domain DUF35_N PF12172.8 KFM73939.1 - 0.16 11.8 3.2 0.3 11.0 3.2 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HTH_Tnp_Tc3_2 PF01498.18 KFM73940.1 - 4.8e-14 52.3 1.4 9.5e-14 51.4 1.4 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73940.1 - 3.1e-09 36.7 0.0 5.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM73940.1 - 1.9e-06 28.4 5.6 3.1e-06 27.7 1.6 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM73940.1 - 0.023 14.6 1.1 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_3 PF01381.22 KFM73940.1 - 0.025 14.6 0.3 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix PAX PF00292.18 KFM73940.1 - 0.051 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain HTH_23 PF13384.6 KFM73940.1 - 0.12 12.2 2.2 2.7 7.9 0.3 3.0 2 1 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 KFM73940.1 - 0.24 11.5 2.8 4.4 7.5 0.5 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM73941.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73941.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73941.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73941.1 - 0.0026 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73941.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain MRC1 PF09444.10 KFM73944.1 - 0.061 13.8 21.3 0.11 13.1 21.3 1.4 1 1 0 1 1 1 0 MRC1-like domain DUF5352 PF17303.2 KFM73944.1 - 0.4 10.5 4.0 0.39 10.6 4.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5352) PDDEXK_6 PF04720.12 KFM73944.1 - 6 6.7 8.7 6.1 6.7 8.7 1.0 1 0 0 1 1 1 0 PDDEXK-like family of unknown function HemY_N PF07219.13 KFM73945.1 - 0.092 12.9 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 HemY protein N-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM73947.1 - 2.1e-16 59.9 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73947.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3459 PF11941.8 KFM73948.1 - 0.0061 16.9 0.0 0.0082 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) DDE_3 PF13358.6 KFM73949.1 - 5.4e-16 58.7 0.1 6.1e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73949.1 - 8.1e-16 58.0 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM73949.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM73949.1 - 0.0026 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73949.1 - 0.016 15.3 0.1 0.066 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM73949.1 - 0.034 14.2 2.6 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix ASC PF00858.24 KFM73950.1 - 7.4e-08 31.8 0.7 8.4e-08 31.6 0.7 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ACOX PF01756.19 KFM73950.1 - 0.0064 16.1 0.0 0.0076 15.8 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA oxidase AGOG PF09171.10 KFM73950.1 - 0.1 11.9 0.2 0.12 11.6 0.2 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Ter PF05472.11 KFM73951.1 - 0.039 13.0 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) HTH_Tnp_Tc3_2 PF01498.18 KFM73952.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73952.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM73952.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM73952.1 - 0.0024 17.6 0.6 0.0069 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM73952.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain 7tm_1 PF00001.21 KFM73953.1 - 6.9e-43 146.9 4.5 9.5e-43 146.4 4.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFM73953.1 - 1.1e-10 41.7 7.9 1.6e-10 41.2 7.9 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFM73953.1 - 2.1e-10 40.7 13.1 2.8e-10 40.3 13.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFM73953.1 - 3.6e-07 29.8 9.1 5.1e-07 29.3 9.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFM73953.1 - 1.2e-05 24.8 11.8 2e-05 24.1 11.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFM73953.1 - 1.9e-05 24.2 11.5 2.8e-05 23.6 11.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4834 PF16118.5 KFM73953.1 - 1.4 10.0 0.0 1.4 10.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) HTH_Tnp_Tc3_2 PF01498.18 KFM73954.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73954.1 - 9.4e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73955.1 - 2.2e-16 59.9 2.2 7.5e-16 58.1 2.2 2.0 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM73955.1 - 1.5e-13 50.7 0.0 3.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM73955.1 - 6.2e-10 38.6 3.0 8.2e-05 22.3 0.1 2.7 2 0 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 KFM73955.1 - 2.5e-09 36.7 6.3 8.8e-07 28.6 0.2 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_29 PF13551.6 KFM73955.1 - 2e-05 24.5 5.1 0.00033 20.6 0.3 2.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM73955.1 - 2.7e-05 24.2 2.5 0.12 12.5 0.5 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KFM73955.1 - 0.00037 20.1 0.2 0.097 12.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_50 PF18024.1 KFM73955.1 - 0.0013 18.2 0.7 0.052 13.2 0.3 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM73955.1 - 0.0018 17.8 1.3 0.0037 16.8 0.1 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 TnsD PF15978.5 KFM73955.1 - 0.0061 15.6 3.8 0.72 8.8 0.5 2.2 2 0 0 2 2 2 2 Tn7-like transposition protein D HTH_24 PF13412.6 KFM73955.1 - 0.011 15.3 1.2 0.6 9.7 0.3 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding UPF0122 PF04297.14 KFM73955.1 - 0.012 15.8 0.1 0.025 14.8 0.1 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_Tnp_ISL3 PF13542.6 KFM73955.1 - 0.013 14.9 1.1 0.049 13.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_46 PF15977.5 KFM73955.1 - 0.23 11.5 1.2 2.6 8.1 0.1 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding HTH_32 PF13565.6 KFM73955.1 - 0.34 11.6 22.6 0.16 12.6 2.0 4.6 3 2 2 5 5 5 0 Homeodomain-like domain HTH_7 PF02796.15 KFM73955.1 - 0.36 10.9 2.9 32 4.7 0.1 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Ribosomal_L7Ae PF01248.26 KFM73958.1 - 4.3e-29 100.1 1.6 5e-29 99.9 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ldh_1_C PF02866.18 KFM73959.1 - 1.1e-51 175.0 0.0 2.8e-51 173.8 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFM73959.1 - 3.9e-47 159.9 0.1 5.7e-47 159.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFM73959.1 - 0.003 16.6 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KFM73959.1 - 0.0031 17.9 0.0 0.0082 16.6 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KFM73959.1 - 0.0032 16.8 0.4 0.02 14.2 0.0 2.4 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 KFM73959.1 - 0.0058 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KFM73959.1 - 0.056 13.7 0.1 3.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 KFM73960.1 - 1.7e-62 211.1 0.0 2.3e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM73960.1 - 3.8e-31 108.3 0.0 5.5e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM73960.1 - 4.2e-05 22.7 0.0 6.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM73960.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM73960.1 - 0.0051 15.6 0.0 0.0098 14.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM73960.1 - 0.04 13.8 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DDE_3 PF13358.6 KFM73961.1 - 7.6e-16 58.2 0.1 7.5e-15 54.9 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM73961.1 - 8.8e-16 57.9 6.5 1.8e-15 56.9 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM73961.1 - 0.00087 19.9 1.5 0.00087 19.9 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM73961.1 - 0.0036 17.1 0.2 0.14 12.0 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM73961.1 - 0.018 15.2 0.1 0.077 13.1 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF668 PF05003.12 KFM73961.1 - 0.032 14.7 0.2 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF668) HTH_29 PF13551.6 KFM73961.1 - 0.042 13.9 0.4 0.042 13.9 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix SP_C-Propep PF08999.10 KFM73962.1 - 0.15 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide HTH_Tnp_Tc3_2 PF01498.18 KFM73963.1 - 3.7e-16 59.1 3.3 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM73963.1 - 6.5e-14 51.9 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.7 KFM73964.1 - 1.7e-21 76.8 0.0 2.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KFM73964.1 - 0.00093 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family zf-HIT PF04438.16 KFM73964.1 - 0.036 13.9 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 HIT zinc finger DDE_3 PF13358.6 KFM73964.1 - 0.094 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-TFIIB PF13453.6 KFM73964.1 - 0.12 11.8 0.4 0.39 10.1 0.2 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger Peptidase_M13_N PF05649.13 KFM73965.1 - 1.7e-35 123.4 0.0 2.2e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 bMG5 PF17972.1 KFM73967.1 - 0.096 13.1 0.9 3.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG5 domain zf-H2C2_2 PF13465.6 KFM73969.1 - 5.9e-69 225.6 74.4 2.1e-08 34.2 1.1 11.8 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73969.1 - 1.7e-39 132.1 93.2 1.5e-05 25.2 3.7 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73969.1 - 1.2e-34 115.9 86.8 0.0003 21.4 3.0 10.4 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM73969.1 - 1.1e-15 57.1 74.9 0.0024 17.8 0.9 10.5 10 0 0 10 10 10 8 C2H2-type zinc finger zf-met PF12874.7 KFM73969.1 - 2.1e-12 47.0 85.4 0.019 15.4 3.4 10.5 10 0 0 10 10 10 7 Zinc-finger of C2H2 type BolA PF01722.18 KFM73969.1 - 8.3e-08 32.4 8.7 0.65 10.3 0.1 5.3 2 1 3 5 5 5 3 BolA-like protein zf-C2H2_jaz PF12171.8 KFM73969.1 - 4.5e-07 30.0 65.8 0.019 15.3 1.0 10.5 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM73969.1 - 6.6e-06 26.1 43.3 0.074 13.1 1.8 9.1 6 3 2 8 8 8 4 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.6 KFM73969.1 - 8.2e-06 25.5 70.5 0.021 14.6 1.9 10.8 11 1 0 11 11 11 5 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM73969.1 - 0.0017 18.1 12.6 0.01 15.6 4.0 9.6 10 0 0 10 10 10 4 zinc-finger C2H2-type Zf_RING PF16744.5 KFM73969.1 - 0.67 10.1 51.3 0.056 13.6 2.2 7.5 2 1 6 8 8 8 0 KIAA1045 RING finger ADK_lid PF05191.14 KFM73969.1 - 1.2 9.2 37.6 6.1 6.9 1.9 6.9 5 1 1 6 6 6 0 Adenylate kinase, active site lid zf-CCHC_2 PF13696.6 KFM73969.1 - 1.4 8.8 33.3 8.6 6.3 0.2 7.8 7 0 0 7 7 7 0 Zinc knuckle FYVE PF01363.21 KFM73969.1 - 2.1 8.5 65.9 0.6 10.3 11.6 6.6 2 2 4 6 6 6 0 FYVE zinc finger C1_4 PF07975.12 KFM73969.1 - 5.2 7.4 63.6 1.1 9.6 3.7 7.3 2 2 5 8 8 8 0 TFIIH C1-like domain THAP PF05485.12 KFM73970.1 - 0.0021 19.0 0.1 0.0035 18.2 0.1 1.5 1 1 1 2 2 2 1 THAP domain HTH_48 PF17906.1 KFM73972.1 - 4.7e-06 26.6 0.1 5.4e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase zf-H2C2_2 PF13465.6 KFM73973.1 - 5.3e-84 273.2 105.3 4.7e-09 36.3 0.5 13.9 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM73973.1 - 4.7e-53 174.8 134.4 1.9e-05 24.9 0.5 14.2 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM73973.1 - 3.5e-38 126.9 119.8 0.001 19.7 1.2 14.2 14 0 0 14 14 14 13 C2H2-type zinc finger zf-met PF12874.7 KFM73973.1 - 1.2e-22 79.5 122.2 0.0029 17.9 3.2 14.0 15 0 0 15 15 14 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM73973.1 - 1.7e-10 40.6 118.5 0.029 14.4 2.2 15.8 16 1 0 16 16 16 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM73973.1 - 2e-05 24.7 97.2 0.036 14.4 4.7 14.2 12 2 1 13 13 13 5 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM73973.1 - 0.0019 18.0 32.8 0.76 9.6 0.0 9.0 3 2 7 11 11 11 3 GAGA factor Tox-HNH-HHH PF15637.6 KFM73973.1 - 0.022 14.9 5.0 52 4.1 0.0 4.6 4 1 1 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Sec23_Sec24 PF04810.15 KFM73973.1 - 0.12 12.5 61.9 1.8 8.7 0.0 12.7 8 3 4 12 12 12 0 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM73973.1 - 0.26 10.9 0.1 0.26 10.9 0.1 10.9 4 4 9 13 13 13 0 MYST family zinc finger domain BolA PF01722.18 KFM73973.1 - 1.5 9.2 23.7 4.2 7.7 0.6 6.7 1 1 8 9 9 9 0 BolA-like protein ADK_lid PF05191.14 KFM73973.1 - 7.9 6.6 61.6 3.1 7.9 2.5 9.3 3 1 6 9 9 9 0 Adenylate kinase, active site lid zf-H2C2_2 PF13465.6 KFM73974.1 - 6e-55 181.3 70.6 7.3e-10 38.8 2.0 10.2 9 1 1 10 10 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM73974.1 - 9.3e-31 103.9 72.6 0.00023 21.7 2.0 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM73974.1 - 2.4e-29 100.1 84.4 1.6e-05 25.1 1.8 8.8 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM73974.1 - 7.7e-11 41.6 49.8 0.00036 20.2 0.3 9.0 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-met PF12874.7 KFM73974.1 - 9.6e-11 41.7 71.6 0.00034 20.9 6.7 9.1 8 1 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM73974.1 - 8.4e-10 38.4 70.2 0.0021 18.0 0.1 9.3 8 2 1 9 9 9 5 C2H2-type zinc finger BolA PF01722.18 KFM73974.1 - 5e-07 29.9 8.2 2.2 8.6 0.1 6.0 1 1 5 6 6 6 3 BolA-like protein zf-C2H2_jaz PF12171.8 KFM73974.1 - 0.0014 18.9 63.9 0.048 14.0 0.5 9.0 8 1 0 8 8 7 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM73974.1 - 0.044 13.6 23.4 0.21 11.4 0.4 6.2 2 2 4 7 7 7 0 GAGA factor SIP1 PF04938.12 KFM73974.1 - 0.052 13.3 0.9 0.074 12.8 0.9 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) BHD_1 PF10403.9 KFM73974.1 - 0.062 13.1 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 zf-C2H2_2 PF12756.7 KFM73974.1 - 0.13 12.6 0.7 0.13 12.6 0.7 7.2 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) Ndufs5 PF10200.9 KFM73974.1 - 0.24 11.7 10.3 1.1 9.6 4.1 3.4 2 2 1 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa YyzF PF14116.6 KFM73974.1 - 1.4 9.0 26.2 7.1 6.7 0.2 7.5 8 0 0 8 8 8 0 YyzF-like protein FYVE PF01363.21 KFM73974.1 - 5.8 7.1 54.0 0.43 10.8 4.4 6.4 1 1 3 5 5 5 0 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 KFM73974.1 - 6 7.0 33.8 0.66 10.1 0.7 7.9 7 1 1 8 8 8 0 Sec23/Sec24 zinc finger zf-C2H2 PF00096.26 KFM73975.1 - 1.1e-08 35.1 14.5 0.00034 20.9 4.8 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 KFM73975.1 - 1.9e-05 24.9 9.1 0.00036 20.8 4.4 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM73975.1 - 2e-05 25.0 12.5 0.00079 20.1 3.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM73975.1 - 0.0001 22.5 7.9 0.14 12.5 3.6 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFM73975.1 - 0.00071 19.9 1.4 0.00071 19.9 1.4 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-MYST PF17772.1 KFM73975.1 - 0.0021 17.6 7.2 0.0039 16.8 0.4 2.1 1 1 1 2 2 2 1 MYST family zinc finger domain zf-FCS PF06467.14 KFM73975.1 - 0.0038 17.1 1.9 0.0038 17.1 1.9 2.1 1 1 1 2 2 2 1 MYM-type Zinc finger with FCS sequence motif zf-Sec23_Sec24 PF04810.15 KFM73975.1 - 0.0072 16.3 3.3 1.6 8.8 0.2 2.2 1 1 1 2 2 2 2 Sec23/Sec24 zinc finger Cytochrome_C7 PF14522.6 KFM73975.1 - 0.0098 15.9 8.7 0.016 15.2 8.7 1.3 1 1 0 1 1 1 1 Cytochrome c7 and related cytochrome c zf_UBZ PF18439.1 KFM73975.1 - 0.021 14.4 8.9 0.19 11.3 0.1 2.6 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-CHY PF05495.12 KFM73975.1 - 0.04 14.4 9.9 0.088 13.3 9.0 1.8 1 1 0 1 1 1 0 CHY zinc finger zf-C2H2_6 PF13912.6 KFM73975.1 - 0.041 13.9 13.9 0.071 13.1 0.7 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger Fer4_21 PF14697.6 KFM73975.1 - 0.051 13.7 3.2 0.076 13.2 3.2 1.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Cas_CXXC_CXXC PF09706.10 KFM73975.1 - 0.13 12.5 3.7 0.67 10.2 0.6 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) FYVE PF01363.21 KFM73975.1 - 0.34 11.1 6.8 3.2 8.0 0.4 2.1 1 1 2 3 3 3 0 FYVE zinc finger PhnA_Zn_Ribbon PF08274.12 KFM73975.1 - 0.7 9.9 6.4 16 5.5 7.2 2.1 1 1 1 2 2 2 0 PhnA Zinc-Ribbon C1_2 PF03107.16 KFM73975.1 - 0.91 9.9 9.7 2.9 8.3 0.8 2.2 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 KFM73975.1 - 2 8.5 11.7 1.9 8.6 5.6 2.2 1 1 1 2 2 2 0 BED zinc finger HRM PF02793.22 KFM73976.1 - 0.0046 17.2 1.5 0.0074 16.6 1.5 1.3 1 0 0 1 1 1 1 Hormone receptor domain Ig_2 PF13895.6 KFM73976.1 - 0.039 14.3 0.0 0.085 13.2 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFM73976.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain DDE_3 PF13358.6 KFM73977.1 - 6.3e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 1 1 2 2 2 2 DDE superfamily endonuclease DNA_pol_D_N PF18018.1 KFM73978.1 - 4.8e-33 114.0 0.0 6e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KFM73979.1 - 1.9e-34 118.9 0.4 2.2e-34 118.6 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B HLH PF00010.26 KFM73980.1 - 6.1e-16 58.1 1.2 6.1e-16 58.1 1.2 2.3 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 KFM73980.1 - 0.25 9.6 4.8 0.27 9.5 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein fn3 PF00041.21 KFM73981.1 - 9.6e-35 118.8 0.8 7.2e-17 61.5 0.3 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM73981.1 - 1.6e-08 35.0 1.7 0.00018 22.0 0.2 2.7 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM73981.1 - 4.3e-06 27.0 0.0 0.024 14.9 0.0 2.5 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III I-set PF07679.16 KFM73981.1 - 0.00038 20.5 0.5 0.0081 16.2 0.0 2.8 3 1 0 3 3 3 1 Immunoglobulin I-set domain DUF2369 PF10179.9 KFM73981.1 - 0.021 15.2 0.0 0.87 10.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) Ig_3 PF13927.6 KFM73981.1 - 0.038 14.6 1.8 0.28 11.8 0.0 2.8 3 2 0 3 3 3 0 Immunoglobulin domain ig PF00047.25 KFM73981.1 - 0.056 13.6 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Glyco_hydro_36C PF16874.5 KFM73981.1 - 0.097 13.2 0.0 11 6.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 36 C-terminal domain SusE PF14292.6 KFM73981.1 - 0.11 12.8 1.0 1.5 9.1 0.1 2.7 2 1 1 3 3 3 0 SusE outer membrane protein Big_4 PF07532.11 KFM73981.1 - 0.54 10.0 3.6 1.1 9.0 0.2 2.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 4) Ig_3 PF13927.6 KFM73982.1 - 1.1e-23 83.6 1.3 8.8e-15 55.1 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM73982.1 - 1.7e-22 79.3 0.3 1.3e-13 50.8 0.1 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM73982.1 - 8.7e-15 54.7 0.2 1.8e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM73982.1 - 6.4e-14 52.0 0.2 4e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM73982.1 - 5.9e-11 42.5 0.8 6e-06 26.4 0.2 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM73982.1 - 8.8e-07 28.4 0.1 0.00016 21.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM73982.1 - 8.1e-05 22.6 0.1 0.029 14.4 0.0 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM73982.1 - 0.00012 22.3 0.1 0.3 11.4 0.1 2.9 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM73982.1 - 0.00038 20.8 0.0 0.23 11.9 0.0 2.3 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFM73982.1 - 0.00092 19.2 0.0 0.25 11.4 0.0 2.2 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFM73982.1 - 0.0077 16.4 1.2 0.18 12.0 0.4 2.7 2 1 0 2 2 2 1 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 KFM73982.1 - 0.0091 16.0 0.1 0.25 11.3 0.0 2.2 2 0 0 2 2 2 1 CD47 immunoglobulin-like domain Ig_3 PF13927.6 KFM73983.1 - 1.5e-35 121.7 0.3 7.9e-17 61.6 0.2 3.1 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM73983.1 - 1.5e-33 114.7 0.0 2.5e-13 49.9 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM73983.1 - 2.7e-25 88.5 0.0 1.7e-13 50.7 0.1 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM73983.1 - 1.3e-21 76.6 0.0 2.4e-10 40.5 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM73983.1 - 1.4e-12 47.7 2.0 0.035 14.3 0.5 4.6 4 1 0 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM73983.1 - 4.6e-06 26.6 0.2 0.023 14.8 0.0 3.3 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM73983.1 - 0.00011 22.5 0.3 0.026 14.9 0.0 3.5 3 1 0 3 3 3 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFM73983.1 - 0.0011 18.5 0.0 0.37 10.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 KFM73983.1 - 0.0016 18.7 0.0 6.6 7.1 0.0 3.7 3 2 1 4 4 4 1 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 KFM73983.1 - 0.0078 16.4 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin C2-set domain BiPBP_C PF06832.12 KFM73983.1 - 0.036 14.1 0.0 0.36 10.9 0.0 2.4 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family Izumo-Ig PF16706.5 KFM73983.1 - 0.077 13.1 0.0 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM73983.1 - 0.14 12.2 0.0 0.59 10.2 0.0 2.0 2 1 0 2 2 2 0 C17orf99 Ig domain E3_UbLigase_EDD PF11547.8 KFM73984.1 - 9.9e-30 102.0 2.7 3.3e-29 100.3 2.7 2.0 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD HTH_48 PF17906.1 KFM73985.1 - 3e-05 24.0 1.1 4.6e-05 23.5 1.1 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM73985.1 - 0.00045 20.8 0.0 0.00074 20.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 KFM73985.1 - 0.00056 19.7 0.0 0.00095 18.9 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KFM73985.1 - 0.00064 19.2 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 KFM73985.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain C2 PF00168.30 KFM73986.1 - 9.2e-17 61.2 0.0 1.4e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 KFM73987.1 - 2.2e-14 53.6 0.0 4.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 KFM73987.1 - 8.9e-13 47.9 0.1 1.5e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM73987.1 - 5.7e-09 36.2 0.1 9.8e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM73987.1 - 2.6e-05 24.4 0.1 6.5e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain DUF4351 PF14261.6 KFM73987.1 - 0.049 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) PTH2 PF01981.16 KFM73988.1 - 1.4e-32 112.4 0.1 2.2e-32 111.8 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 UBA PF00627.31 KFM73988.1 - 0.00033 20.5 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Calponin PF00402.18 KFM73988.1 - 0.055 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Calponin family repeat Metallophos PF00149.28 KFM73989.1 - 2.6e-05 24.8 0.0 3.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Syntaphilin PF15290.6 KFM73990.1 - 1.5e-08 34.7 4.6 1.5e-08 34.7 4.6 2.9 1 1 1 2 2 2 1 Golgi-localised syntaxin-1-binding clamp Spc7 PF08317.11 KFM73990.1 - 1.1e-05 24.5 28.3 1.4e-05 24.2 6.9 2.7 2 1 1 3 3 3 2 Spc7 kinetochore protein GRIP PF01465.20 KFM73990.1 - 8.8e-05 22.3 0.1 0.00023 21.0 0.1 1.8 1 0 0 1 1 1 1 GRIP domain TetR_C_24 PF17932.1 KFM73990.1 - 0.016 15.4 4.2 0.051 13.8 0.5 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Sec8_exocyst PF04048.14 KFM73990.1 - 0.052 13.4 12.2 0.22 11.4 2.6 3.3 2 2 0 2 2 2 0 Sec8 exocyst complex component specific domain Tropomyosin PF00261.20 KFM73990.1 - 0.12 11.8 30.2 0.036 13.4 7.0 3.5 2 1 0 3 3 3 0 Tropomyosin Baculo_PEP_C PF04513.12 KFM73990.1 - 0.13 12.3 3.2 0.77 9.8 0.2 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1796 PF08795.10 KFM73990.1 - 0.15 12.0 3.0 0.46 10.4 3.0 1.8 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Exonuc_VII_L PF02601.15 KFM73990.1 - 0.18 11.3 27.7 0.81 9.2 4.6 2.7 2 1 0 2 2 2 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 KFM73990.1 - 0.42 10.8 37.4 0.036 14.3 9.8 3.3 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KFM73990.1 - 0.72 9.9 10.6 0.41 10.7 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.12 KFM73990.1 - 1 9.3 4.2 4.5 7.3 0.1 3.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.11 KFM73990.1 - 2.3 8.7 13.1 0.73 10.3 0.3 4.0 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Rubrerythrin PF02915.17 KFM73990.1 - 2.6 8.4 12.4 0.048 14.0 1.0 2.8 2 1 2 4 4 4 0 Rubrerythrin SHE3 PF17078.5 KFM73990.1 - 3.2 7.4 32.5 0.054 13.2 10.2 3.4 3 2 1 4 4 4 0 SWI5-dependent HO expression protein 3 HrpB7 PF09486.10 KFM73990.1 - 3.5 8.0 19.9 0.1 13.0 1.2 3.1 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) ApoO PF09769.9 KFM73990.1 - 4.7 7.2 4.8 3.7 7.5 0.5 2.5 2 1 0 2 2 2 0 Apolipoprotein O DUF5082 PF16888.5 KFM73990.1 - 4.7 7.5 21.1 9.1 6.6 6.9 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) YtxH PF12732.7 KFM73990.1 - 6.4 7.4 5.5 3 8.5 0.3 3.0 2 1 1 3 3 3 0 YtxH-like protein TMPIT PF07851.13 KFM73990.1 - 8.5 5.5 20.8 3.2 6.9 4.6 2.7 2 1 1 3 3 3 0 TMPIT-like protein Thioredoxin PF00085.20 KFM73991.1 - 3.1e-81 268.0 2.5 9.8e-28 96.2 0.4 3.1 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 KFM73991.1 - 1.7e-17 63.8 0.6 4.2e-06 27.2 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 KFM73991.1 - 6.7e-09 35.5 0.1 0.042 13.2 0.0 3.4 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFM73991.1 - 2.4e-08 34.2 6.0 0.094 13.1 0.0 5.6 3 2 3 6 6 6 3 Thioredoxin-like Thioredoxin_7 PF13899.6 KFM73991.1 - 4.1e-08 33.3 1.9 0.0062 16.7 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_3 PF13192.6 KFM73991.1 - 1.4e-05 25.0 0.3 0.022 14.8 0.1 3.0 3 0 0 3 3 3 2 Thioredoxin domain TraF PF13728.6 KFM73991.1 - 0.0002 21.3 0.0 3.4 7.4 0.0 3.3 3 0 0 3 3 3 2 F plasmid transfer operon protein HyaE PF07449.11 KFM73991.1 - 0.00029 20.7 0.0 0.12 12.4 0.0 3.3 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 KFM73991.1 - 0.0027 17.4 0.6 0.67 9.7 0.1 2.4 2 0 0 2 2 2 2 Redoxin Glutaredoxin PF00462.24 KFM73991.1 - 0.0034 17.6 2.7 4 7.7 0.1 3.7 3 1 0 3 3 3 1 Glutaredoxin Ribosomal_60s PF00428.19 KFM73992.1 - 7.5e-29 100.2 5.8 9e-29 99.9 5.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DHHA1 PF02272.19 KFM73992.1 - 0.072 13.5 2.5 0.11 13.0 2.5 1.4 1 1 0 1 1 1 0 DHHA1 domain Cytomega_UL84 PF06284.11 KFM73992.1 - 0.17 10.3 0.3 0.19 10.1 0.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Vta1 PF04652.16 KFM73993.1 - 8.9e-51 171.7 0.5 1.8e-49 167.5 0.2 2.0 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KFM73993.1 - 1.3e-18 66.4 0.1 1.3e-18 66.4 0.1 1.8 2 0 0 2 2 2 1 Vta1 C-terminal domain 4F5 PF04419.14 KFM73994.1 - 5.7e-11 43.1 9.6 5.7e-11 43.1 9.6 2.2 2 0 0 2 2 2 2 4F5 protein family GCV_T PF01571.21 KFM73995.1 - 1.3e-15 57.5 0.0 1.9e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Mito_carr PF00153.27 KFM73996.1 - 2.7e-78 258.0 1.1 4.5e-26 90.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NT-C2 PF10358.9 KFM73998.1 - 9.3e-27 93.5 0.0 1.4e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Macoilin PF09726.9 KFM73998.1 - 2.6 6.5 4.6 3.5 6.1 4.6 1.1 1 0 0 1 1 1 0 Macoilin family GST_N PF02798.20 KFM73999.1 - 5.9e-12 45.8 0.0 2.1e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFM73999.1 - 9.8e-11 41.7 0.1 1.8e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM73999.1 - 1.6e-10 41.0 0.2 2.6e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM73999.1 - 1.8e-10 41.1 0.0 3.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFM73999.1 - 4.7e-06 26.5 0.1 1.3e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFM73999.1 - 9.6e-06 25.8 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HTH_32 PF13565.6 KFM74000.1 - 0.08 13.6 2.4 0.21 12.2 0.4 2.6 1 1 2 3 3 3 0 Homeodomain-like domain Transposase_1 PF01359.18 KFM74000.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Transposase (partial DDE domain) Transposase_1 PF01359.18 KFM74002.1 - 3.3e-16 58.9 0.2 5.1e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) DUF1668 PF07893.13 KFM74002.1 - 0.065 12.6 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) PH_3 PF14593.6 KFM74002.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 PH domain DNA_pol3_theta PF06440.11 KFM74004.1 - 0.031 13.9 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III, theta subunit DUF5395 PF17373.2 KFM74005.1 - 0.041 14.5 0.0 0.26 12.0 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5395) DUF4116 PF13475.6 KFM74005.1 - 0.077 12.7 0.1 0.22 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) RNase_H PF00075.24 KFM74007.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.5 1 1 0 1 1 1 0 RNase H Metallophos PF00149.28 KFM74008.1 - 4.2e-21 76.4 1.0 5.3e-21 76.0 1.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM74008.1 - 0.00037 20.7 0.1 0.035 14.3 0.1 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF5553 PF17707.1 KFM74008.1 - 0.11 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5553) DUF4552 PF15089.6 KFM74010.1 - 0.0024 17.0 0.1 0.0036 16.4 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4552) Cpn60_TCP1 PF00118.24 KFM74011.1 - 0.0051 15.5 0.0 0.0051 15.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KFM74012.1 - 0.0013 17.5 0.0 0.0013 17.4 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family KH_1 PF00013.29 KFM74013.1 - 6.9e-64 211.6 14.5 4.1e-17 61.8 0.2 4.3 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFM74013.1 - 1.8e-17 62.9 9.0 5.5e-06 26.1 0.2 4.6 4 0 0 4 4 4 4 KH domain RRM_1 PF00076.22 KFM74013.1 - 4.6e-12 45.6 0.0 8.2e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_4 PF13083.6 KFM74013.1 - 4.5e-11 42.5 7.4 0.0016 18.3 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 KFM74013.1 - 1.5e-09 37.8 6.1 0.25 11.4 0.1 4.4 4 0 0 4 4 4 4 NusA-like KH domain MOEP19 PF16005.5 KFM74013.1 - 6.3e-09 35.7 0.0 0.082 12.9 0.0 4.4 3 1 1 4 4 4 2 KH-like RNA-binding domain UPF0126 PF03458.13 KFM74013.1 - 0.025 14.4 0.7 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 UPF0126 domain Nup35_RRM_2 PF14605.6 KFM74013.1 - 0.058 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFM74013.1 - 0.067 13.1 0.0 0.33 10.8 0.0 2.2 2 1 0 2 2 2 0 Occluded RNA-recognition motif WAPL PF07814.13 KFM74016.1 - 1.5e-53 181.9 11.6 1.5e-53 181.9 11.6 1.5 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin Atx10homo_assoc PF09759.9 KFM74016.1 - 0.015 15.3 0.6 0.086 12.9 0.2 2.5 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF4410 PF14366.6 KFM74016.1 - 0.22 11.4 0.4 0.41 10.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) DUF4337 PF14235.6 KFM74016.1 - 0.27 11.3 3.9 0.55 10.3 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) WAPL PF07814.13 KFM74017.1 - 1.6e-22 79.9 0.0 1.6e-22 79.9 0.0 2.3 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin zf-Tim10_DDP PF02953.15 KFM74018.1 - 6.2e-18 64.2 6.6 9.4e-18 63.6 6.6 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vicilin_N PF04702.12 KFM74018.1 - 0.11 12.3 4.8 0.13 12.1 4.8 1.2 1 0 0 1 1 1 0 Vicilin N terminal region LisH_2 PF16045.5 KFM74021.1 - 0.012 14.6 4.0 0.013 14.5 0.2 2.6 3 0 0 3 3 3 0 LisH Ribosomal_L26 PF16906.5 KFM74024.1 - 4.8e-40 135.9 4.7 6.6e-40 135.5 4.7 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KFM74024.1 - 5.7e-08 32.4 5.1 5.7e-08 32.4 5.1 1.9 2 0 0 2 2 2 1 KOW motif BTB PF00651.31 KFM74025.1 - 9.9e-24 83.7 0.9 2.6e-23 82.4 0.5 1.9 1 1 1 2 2 2 1 BTB/POZ domain C1_1 PF00130.22 KFM74027.1 - 7.3e-06 25.8 8.7 1.1e-05 25.2 8.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Tropomodulin PF03250.14 KFM74027.1 - 0.093 12.8 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Tropomodulin C1_2 PF03107.16 KFM74027.1 - 0.17 12.2 5.7 0.32 11.4 5.7 1.5 1 0 0 1 1 1 0 C1 domain Sgf11 PF08209.11 KFM74027.1 - 1.8 8.2 6.6 6.6 6.4 2.0 2.4 1 1 1 2 2 2 0 Sgf11 (transcriptional regulation protein) PH_16 PF17838.1 KFM74028.1 - 3.5e-39 133.5 1.0 1e-38 132.0 0.2 2.3 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.20 KFM74028.1 - 1.2e-33 116.9 2.5 1.2e-33 116.9 2.5 2.5 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFM74028.1 - 0.062 13.8 0.1 0.19 12.2 0.1 1.9 1 0 0 1 1 1 0 PH domain DUF5344 PF17279.2 KFM74028.1 - 0.59 10.7 6.1 22 5.7 0.2 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5344) HTH_Tnp_Tc3_2 PF01498.18 KFM74029.1 - 8.7e-16 57.9 1.5 1.7e-15 57.0 1.5 1.4 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM74029.1 - 0.00078 19.2 0.7 0.0044 16.8 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74029.1 - 0.0017 18.9 6.6 0.024 15.2 2.3 2.2 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM74029.1 - 0.0098 15.9 1.4 0.1 12.6 0.1 2.4 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_3 PF01381.22 KFM74029.1 - 0.049 13.7 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix MarR_2 PF12802.7 KFM74029.1 - 0.052 13.4 1.3 0.48 10.4 0.1 2.7 1 1 1 2 2 2 0 MarR family PAX PF00292.18 KFM74029.1 - 0.058 13.3 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain HTH_24 PF13412.6 KFM74029.1 - 0.066 12.8 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding RVT_1 PF00078.27 KFM74030.1 - 0.085 12.4 0.0 0.088 12.3 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCCH PF00642.24 KFM74031.1 - 3.7e-20 71.3 43.3 9.2e-07 28.6 0.5 5.8 6 0 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM74031.1 - 8.2e-16 57.5 53.7 9.8e-07 28.6 2.6 7.0 6 1 0 6 6 6 4 Zinc finger domain zf-CCCH_3 PF15663.5 KFM74031.1 - 5.7e-12 45.8 23.2 1.2e-09 38.4 8.1 2.6 2 1 1 3 3 3 2 Zinc-finger containing family Torus PF16131.5 KFM74031.1 - 1.8e-11 44.7 30.7 0.00045 20.9 0.5 5.4 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 KFM74031.1 - 2.6e-11 43.1 38.1 4.4e-06 26.4 0.3 5.0 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCHC PF00098.23 KFM74031.1 - 6.2e-08 32.4 21.9 2.3e-06 27.4 3.0 4.0 4 0 0 4 4 4 2 Zinc knuckle zf-CCCH_2 PF14608.6 KFM74031.1 - 0.00024 21.4 50.1 0.039 14.4 1.2 6.8 7 1 0 7 7 7 4 RNA-binding, Nab2-type zinc finger zf-CCHC_3 PF13917.6 KFM74031.1 - 0.00047 20.0 4.0 0.061 13.3 0.3 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 KFM74031.1 - 0.036 13.8 2.4 0.036 13.8 2.4 3.4 3 0 0 3 3 3 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 KFM74031.1 - 0.51 10.2 20.9 0.096 12.5 2.2 4.8 4 0 0 4 4 4 0 Zinc knuckle zf-C3H1 PF10650.9 KFM74031.1 - 8.8 6.2 20.3 5 6.9 0.4 5.3 4 1 0 4 4 4 0 Putative zinc-finger domain TMEM208_SND2 PF05620.11 KFM74032.1 - 2.9e-40 137.8 6.1 3.2e-40 137.7 6.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 HTH_Tnp_Tc3_2 PF01498.18 KFM74033.1 - 2.7e-14 53.1 1.0 5.2e-14 52.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74033.1 - 3.1e-14 53.0 0.0 4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 KFM74035.1 - 5.8e-31 106.5 0.0 1.6e-30 105.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM74035.1 - 3.3e-28 98.7 1.3 7.1e-28 97.6 0.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM74035.1 - 4.7e-28 97.6 0.0 1.4e-27 96.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM74035.1 - 7.1e-20 70.9 0.2 2.8e-19 69.0 0.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFM74035.1 - 6e-18 65.2 0.0 1.6e-15 57.3 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KFM74035.1 - 2.7e-09 37.5 0.0 8.7e-09 35.8 0.0 1.9 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM74035.1 - 1.4e-05 25.7 0.0 3.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM74035.1 - 1.6e-05 25.1 0.0 4.6e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KFM74035.1 - 4.7e-05 23.5 1.0 0.00012 22.2 1.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KFM74035.1 - 7.8e-05 22.5 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_3 PF13456.6 KFM74035.1 - 0.0025 17.6 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Asp_protease PF09668.10 KFM74035.1 - 0.0031 17.3 0.1 0.007 16.2 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease BH4 PF02180.17 KFM74035.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 DUF3437 PF11919.8 KFM74035.1 - 0.13 12.1 6.6 1.7 8.6 1.3 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF3437) BEN PF10523.9 KFM74035.1 - 0.13 12.5 0.5 3.5 7.9 0.0 3.3 2 0 0 2 2 2 0 BEN domain HTH_48 PF17906.1 KFM74038.1 - 6.3e-18 64.6 0.6 1.1e-17 63.9 0.6 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Asp_protease_2 PF13650.6 KFM74040.1 - 5.2e-06 27.0 0.1 1.1e-05 26.0 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM74040.1 - 5e-05 23.8 0.1 0.00014 22.3 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_5 PF14787.6 KFM74040.1 - 0.001 18.7 2.1 0.001 18.7 2.1 1.8 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 KFM74040.1 - 0.012 15.7 3.6 0.012 15.7 3.6 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 KFM74040.1 - 0.024 14.6 1.1 0.024 14.6 1.1 2.4 2 0 0 2 2 2 0 Zinc knuckle Asp_protease PF09668.10 KFM74040.1 - 0.15 11.9 1.9 0.35 10.7 0.2 2.2 2 0 0 2 2 2 0 Aspartyl protease 7tm_1 PF00001.21 KFM74041.1 - 7.8e-15 54.9 12.2 1.1e-14 54.4 12.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SUR7 PF06687.12 KFM74041.1 - 5.2e-05 23.0 8.7 0.0064 16.2 1.1 2.2 2 0 0 2 2 2 2 SUR7/PalI family DUF3377 PF11857.8 KFM74041.1 - 0.0014 18.5 0.5 0.0014 18.5 0.5 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3377) 7TM_GPCR_Srx PF10328.9 KFM74041.1 - 0.014 15.0 13.5 0.021 14.4 13.5 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx CcmH PF03918.14 KFM74041.1 - 0.059 12.7 0.0 0.059 12.7 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein YrhC PF14143.6 KFM74041.1 - 10 6.3 6.6 2.4 8.3 2.6 2.1 2 0 0 2 2 2 0 YrhC-like protein Flu_NP PF00506.18 KFM74042.1 - 0.033 12.9 0.0 0.033 12.9 0.0 1.0 1 0 0 1 1 1 0 Influenza virus nucleoprotein HTH_Tnp_Tc3_2 PF01498.18 KFM74043.1 - 4.9e-16 58.7 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74043.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74043.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74043.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74043.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain BTB PF00651.31 KFM74044.1 - 8.9e-24 83.9 0.2 1.4e-23 83.2 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain DDE_1 PF03184.19 KFM74046.1 - 1.4e-11 44.4 1.3 1.7e-11 44.1 0.4 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease TGS PF02824.21 KFM74046.1 - 0.082 13.0 0.8 11 6.1 0.0 2.3 2 0 0 2 2 2 0 TGS domain PH_17 PF18012.1 KFM74049.1 - 1.8e-09 37.2 0.1 2e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 PH domain PH PF00169.29 KFM74049.1 - 0.0021 18.5 0.0 0.0023 18.4 0.0 1.1 1 0 0 1 1 1 1 PH domain DUF4720 PF15846.5 KFM74049.1 - 0.16 11.8 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) PDZ PF00595.24 KFM74050.1 - 6.1e-15 55.3 0.9 8.9e-15 54.8 0.9 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM74050.1 - 3.4e-06 26.8 0.1 5.3e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM74050.1 - 0.00046 20.4 0.0 0.00082 19.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain CDP-OH_P_transf PF01066.21 KFM74051.1 - 3.5e-17 62.9 0.0 3.5e-17 62.9 0.0 3.2 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase RAI16-like PF10257.9 KFM74053.1 - 6.7e-40 137.1 0.3 8.4e-40 136.7 0.3 1.0 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein FCH PF00611.23 KFM74054.1 - 7.8e-16 58.1 0.3 2.6e-15 56.5 0.3 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFM74054.1 - 2.4e-10 39.9 0.4 2.4e-10 39.9 0.4 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFM74054.1 - 6.7e-06 25.9 0.4 6.7e-06 25.9 0.4 2.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 KFM74054.1 - 0.0026 17.4 0.0 0.0066 16.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3BP5 PF05276.14 KFM74054.1 - 0.023 14.5 9.6 0.37 10.6 3.0 2.5 2 1 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) DUF4041 PF13250.6 KFM74054.1 - 0.085 12.7 0.3 0.45 10.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) ARD PF03079.14 KFM74054.1 - 0.34 11.1 8.6 0.13 12.4 4.4 2.4 1 1 1 2 2 2 0 ARD/ARD' family Rho_Binding PF08912.11 KFM74054.1 - 1 10.2 6.1 2.6 8.9 0.6 3.3 2 0 0 2 2 2 0 Rho Binding Nse4_C PF08743.10 KFM74055.1 - 1.2e-21 76.8 0.1 1.1e-20 73.7 0.1 2.3 2 0 0 2 2 2 1 Nse4 C-terminal EF-hand_6 PF13405.6 KFM74056.1 - 1.6e-05 24.4 0.0 7.7e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFM74056.1 - 0.00077 18.8 0.0 0.0036 16.8 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFM74056.1 - 0.0013 19.1 0.1 0.0013 19.1 0.1 3.9 3 2 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM74056.1 - 0.0049 16.3 0.6 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 EF hand RVT_connect PF06815.13 KFM74056.1 - 0.1 12.9 3.0 0.97 9.7 2.2 2.4 1 1 1 2 2 2 0 Reverse transcriptase connection domain Glyco_hydro_88 PF07470.13 KFM74056.1 - 0.13 11.4 1.2 0.3 10.1 1.2 1.6 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 rve PF00665.26 KFM74057.1 - 4e-09 36.7 0.0 5.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain SSB PF00436.25 KFM74060.1 - 1.3e-26 92.7 0.0 1.6e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Rax2 PF12768.7 KFM74060.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Ribosomal_S9 PF00380.19 KFM74061.1 - 3.9e-28 98.4 0.0 4.7e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Glycos_transf_2 PF00535.26 KFM74062.1 - 6.8e-36 123.6 0.0 8.3e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFM74062.1 - 5e-13 49.5 0.0 6.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFM74062.1 - 3.2e-06 26.8 0.0 4.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFM74062.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KFM74062.1 - 0.018 15.6 0.0 0.036 14.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 PIH1_CS PF18201.1 KFM74063.1 - 1.7e-11 44.3 0.0 3.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain CS PF04969.16 KFM74063.1 - 0.053 14.5 0.2 0.26 12.4 0.2 2.1 1 1 1 2 2 2 0 CS domain Bep_C_terminal PF17841.1 KFM74063.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) EF-hand_1 PF00036.32 KFM74065.1 - 2e-18 64.5 13.2 0.0002 20.7 0.4 5.7 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 KFM74065.1 - 1.9e-13 50.6 19.1 4.2e-07 30.3 1.9 3.8 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFM74065.1 - 2.5e-13 48.8 17.7 0.0015 18.3 0.2 5.6 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 KFM74065.1 - 3.5e-11 42.0 17.5 0.00012 21.4 0.4 5.0 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFM74065.1 - 4.6e-07 29.6 12.7 0.16 11.8 0.2 4.8 5 0 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM74065.1 - 2.7 8.4 18.9 3 8.2 7.8 3.4 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFM74065.1 - 3.3 7.6 9.4 11 5.9 0.0 4.0 4 1 1 5 5 5 0 EF hand Cation_efflux PF01545.21 KFM74066.1 - 4.3e-23 82.1 16.6 7.2e-23 81.4 16.6 1.3 1 1 0 1 1 1 1 Cation efflux family MARVEL PF01284.23 KFM74066.1 - 0.055 13.5 6.8 0.2 11.7 0.7 2.7 1 1 2 3 3 3 0 Membrane-associating domain CX PF01705.19 KFM74066.1 - 0.37 11.4 8.4 8.3 7.0 3.5 2.4 2 0 0 2 2 2 0 CX module DUF2975 PF11188.8 KFM74066.1 - 0.43 10.5 11.5 0.066 13.1 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) GTP1_OBG PF01018.22 KFM74067.1 - 2.1e-48 163.9 5.8 2.7e-48 163.5 5.8 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 KFM74067.1 - 8.3e-26 90.3 0.0 1.9e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM74067.1 - 3.6e-11 42.8 0.0 2.1e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KFM74067.1 - 1.5e-05 24.5 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFM74067.1 - 0.0002 21.0 0.0 0.00036 20.2 0.0 1.4 1 1 0 1 1 1 1 Ras family NOG1 PF06858.14 KFM74067.1 - 0.0013 18.5 0.0 0.0034 17.1 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) Dynamin_N PF00350.23 KFM74067.1 - 0.015 15.3 0.0 7 6.7 0.0 2.3 1 1 1 2 2 2 0 Dynamin family ABC_tran PF00005.27 KFM74067.1 - 0.042 14.4 0.0 0.071 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KFM74067.1 - 0.15 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFM74067.1 - 0.17 11.4 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pep3_Vps18 PF05131.14 KFM74068.1 - 1.7e-13 50.6 0.2 5.9e-13 48.9 0.2 2.0 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KFM74068.1 - 6.4e-13 48.8 14.6 2.2e-10 40.6 5.6 4.1 3 1 1 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KFM74068.1 - 9.9e-08 32.4 1.6 2.2e-07 31.3 0.7 2.2 2 0 0 2 2 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 KFM74068.1 - 0.00014 21.4 0.9 0.00014 21.4 0.9 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KFM74068.1 - 0.0064 16.4 0.9 0.018 15.0 0.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFM74068.1 - 0.034 13.9 4.4 0.12 12.2 4.4 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 KFM74068.1 - 0.04 14.3 1.2 0.13 12.6 1.2 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KFM74068.1 - 0.046 13.6 2.0 0.14 12.0 2.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM74068.1 - 0.06 13.6 1.2 0.19 12.0 1.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain IL3 PF02059.15 KFM74068.1 - 0.066 13.3 0.2 0.26 11.3 0.2 2.0 1 0 0 1 1 1 0 Interleukin-3 zf-ANAPC11 PF12861.7 KFM74068.1 - 0.14 12.2 0.2 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KFM74068.1 - 0.18 11.7 1.1 0.57 10.1 1.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 KFM74068.1 - 0.26 11.5 2.4 0.46 10.7 1.2 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain YabA PF06156.13 KFM74068.1 - 0.27 11.9 5.0 0.46 11.1 0.1 3.4 4 0 0 4 4 3 0 Initiation control protein YabA TPR_8 PF13181.6 KFM74068.1 - 0.84 10.0 12.6 23 5.5 0.5 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5101 PF17031.5 KFM74068.1 - 2.4 8.3 7.5 0.33 11.1 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5101) zf-C3H2C3 PF17122.5 KFM74068.1 - 2.9 8.0 7.6 0.66 10.1 3.7 2.0 2 0 0 2 2 1 0 Zinc-finger TPR_1 PF00515.28 KFM74068.1 - 6.6 6.7 7.8 28 4.8 1.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat BLOC1_2 PF10046.9 KFM74069.1 - 0.21 11.9 5.2 1.2 9.5 5.2 2.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CREPT PF16566.5 KFM74069.1 - 0.58 10.3 9.8 0.19 11.9 6.2 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Sec1 PF00995.23 KFM74070.1 - 6.7e-18 65.2 0.4 3.4e-16 59.6 0.4 2.1 1 1 0 1 1 1 1 Sec1 family Bap31 PF05529.12 KFM74071.1 - 1.9e-40 137.9 11.0 2.4e-40 137.5 11.0 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF1385 PF07136.11 KFM74071.1 - 0.0038 16.5 4.2 0.0042 16.4 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1385) LMF1 PF06762.14 KFM74071.1 - 0.042 13.0 3.5 0.051 12.7 3.5 1.1 1 0 0 1 1 1 0 Lipase maturation factor DUF4083 PF13314.6 KFM74071.1 - 0.058 13.3 0.3 0.058 13.3 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) ATP-synt_C PF00137.21 KFM74073.1 - 1.1e-10 41.7 12.4 2e-10 40.9 12.4 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DDE_3 PF13358.6 KFM74075.1 - 7.7e-06 25.7 0.0 8.4e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease UPF0047 PF01894.17 KFM74076.1 - 1.5e-14 54.1 0.0 1.6e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 UCH_1 PF13423.6 KFM74077.1 - 6.6e-93 311.8 8.5 8.6e-93 311.4 8.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KFM74077.1 - 2.2e-21 77.1 0.0 3.7e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KFM74077.1 - 3.1e-07 30.2 4.1 2.2e-06 27.4 4.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_pol_A_exo1 PF01612.20 KFM74077.1 - 0.0031 17.2 0.1 0.0076 16.0 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease zf-CCCH_2 PF14608.6 KFM74077.1 - 0.089 13.3 2.7 0.24 11.9 2.7 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger eIF2A PF08662.11 KFM74078.1 - 0.059 13.2 0.1 0.52 10.2 0.0 2.3 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A zf-C2H2 PF00096.26 KFM74079.1 - 7.3e-14 51.4 36.8 5.1e-05 23.5 0.9 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74079.1 - 3e-11 43.2 30.5 0.0014 19.3 2.9 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM74079.1 - 2.7e-06 27.5 36.9 0.00014 22.1 1.1 5.7 6 0 0 6 6 5 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFM74079.1 - 5.6e-06 26.2 21.1 0.00047 20.1 2.3 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFM74079.1 - 0.00027 21.5 7.1 0.63 10.7 0.1 3.9 1 1 3 4 4 4 2 FOXP coiled-coil domain MAGP PF05507.11 KFM74079.1 - 0.0055 17.1 0.5 0.0088 16.5 0.5 1.5 1 0 0 1 1 1 1 Microfibril-associated glycoprotein (MAGP) zf-C2H2_jaz PF12171.8 KFM74079.1 - 0.0064 16.8 8.8 0.13 12.6 0.6 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KFM74079.1 - 0.015 15.9 6.5 0.2 12.4 0.8 3.0 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 KFM74079.1 - 0.019 15.2 9.3 0.019 15.2 9.3 3.6 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-met PF12874.7 KFM74079.1 - 0.11 12.9 0.9 0.11 12.9 0.9 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.12 KFM74079.1 - 0.2 11.7 16.6 0.95 9.5 0.0 3.2 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Yippee-Mis18 PF03226.14 KFM74079.1 - 0.27 11.5 6.8 0.44 10.8 5.2 2.1 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2HE PF16278.5 KFM74079.1 - 2.7 8.5 11.0 3.2 8.3 3.5 3.0 3 1 0 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger DHHC PF01529.20 KFM74080.1 - 1.6e-30 106.0 12.8 1.6e-30 106.0 12.8 2.9 2 2 0 2 2 2 1 DHHC palmitoyltransferase DUF2207 PF09972.9 KFM74080.1 - 6.4 5.4 11.0 3.6 6.3 1.5 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) L51_S25_CI-B8 PF05047.16 KFM74082.1 - 0.0004 20.3 0.1 0.00076 19.3 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2441 PF10386.9 KFM74082.1 - 0.055 13.5 0.0 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2441) Glft2_N PF17994.1 KFM74082.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Galactofuranosyltransferase 2 N-terminal Histone_H2A_C PF16211.5 KFM74083.1 - 9.9e-14 50.8 0.3 3.1e-13 49.2 0.3 1.9 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM74083.1 - 1.1e-06 29.0 2.1 5.3e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Macro PF01661.21 KFM74084.1 - 4e-09 36.5 0.1 5.9e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Macro domain DDE_1 PF03184.19 KFM74085.1 - 4.5e-27 94.8 0.1 7.6e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM74085.1 - 2.4e-11 43.5 0.1 5e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM74086.1 - 9.8e-11 41.6 0.0 1.6e-10 40.9 0.0 1.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74087.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74087.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74087.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74087.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74087.1 - 2 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain WD40 PF00400.32 KFM74088.1 - 3e-16 59.5 5.5 2.7e-06 28.0 0.3 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM74088.1 - 3.9e-06 27.1 0.0 0.36 11.2 0.0 3.5 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain SF-assemblin PF06705.11 KFM74089.1 - 0.016 14.5 0.8 0.036 13.4 0.8 1.5 1 0 0 1 1 1 0 SF-assemblin/beta giardin Arfaptin PF06456.13 KFM74089.1 - 0.018 14.6 2.4 0.031 13.9 2.4 1.4 1 0 0 1 1 1 0 Arfaptin-like domain DUF4047 PF13256.6 KFM74089.1 - 0.028 14.6 1.8 0.039 14.1 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Jnk-SapK_ap_N PF09744.9 KFM74089.1 - 0.038 14.2 2.8 0.068 13.4 2.8 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Bacillus_HBL PF05791.11 KFM74089.1 - 0.11 12.3 2.8 0.18 11.6 2.8 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.12 KFM74089.1 - 0.16 12.1 4.2 0.31 11.1 4.2 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 KFM74089.1 - 0.32 11.0 2.9 2.5 8.1 1.7 2.6 2 1 1 3 3 3 0 Laminin Domain II DUF4898 PF16239.5 KFM74090.1 - 0.51 10.3 5.2 1.1 9.2 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4898) Galactosyl_T PF01762.21 KFM74091.1 - 7.2e-20 71.6 0.1 9.7e-20 71.2 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase WD40 PF00400.32 KFM74092.1 - 0.0013 19.5 0.8 0.0083 17.0 0.8 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Thioredoxin_8 PF13905.6 KFM74094.1 - 2.5e-28 98.2 0.0 3.2e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KFM74094.1 - 3.1e-11 43.2 0.0 3.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 KFM74094.1 - 2.8e-10 40.2 0.0 3.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM74094.1 - 4.1e-09 36.3 0.0 5.3e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 KFM74094.1 - 1.4e-05 25.5 0.0 2.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KFM74094.1 - 0.0019 18.0 0.1 0.036 13.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin TraF PF13728.6 KFM74094.1 - 0.0083 16.0 0.1 0.044 13.6 0.1 1.9 1 1 0 1 1 1 1 F plasmid transfer operon protein SCO1-SenC PF02630.14 KFM74094.1 - 0.0086 16.0 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC DUF953 PF06110.11 KFM74094.1 - 0.022 14.4 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 KFM74094.1 - 0.092 13.0 0.2 1.3 9.2 0.2 2.2 1 1 0 1 1 1 0 Glutaredoxin Pkinase PF00069.25 KFM74096.1 - 2.1e-34 119.1 0.0 2.5e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM74096.1 - 5.1e-23 81.7 0.0 1.5e-21 76.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase EBP PF05241.12 KFM74096.1 - 0.043 13.3 0.1 0.067 12.6 0.1 1.3 1 0 0 1 1 1 0 Emopamil binding protein hGDE_N PF14699.6 KFM74097.1 - 1.3e-16 60.5 0.0 1.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme hDGE_amylase PF14701.6 KFM74098.1 - 1.3e-40 139.9 0.1 1.4e-40 139.8 0.1 1.0 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase PF00128.24 KFM74098.1 - 0.00014 21.5 0.0 0.00016 21.4 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KFM74099.1 - 8.4e-10 38.3 0.0 8.4e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain hDGE_amylase PF14701.6 KFM74100.1 - 3.3e-57 194.5 0.1 3.8e-57 194.3 0.1 1.0 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain RNase_H PF00075.24 KFM74101.1 - 0.00023 21.4 0.0 0.00025 21.2 0.0 1.1 1 0 0 1 1 1 1 RNase H hGDE_central PF14702.6 KFM74102.1 - 1.1e-05 25.3 0.0 1.2e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_central PF14702.6 KFM74103.1 - 5e-40 137.8 0.2 6e-40 137.5 0.2 1.1 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme GDE_C PF06202.14 KFM74104.1 - 6.5e-79 265.6 0.0 7.9e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase EAGR_box PF16713.5 KFM74104.1 - 0.47 10.2 3.9 9.5 6.0 0.2 2.7 2 0 0 2 2 2 0 Enriched in aromatic and glycine Residues box CBM_14 PF01607.24 KFM74105.1 - 2.5e-23 82.0 18.9 1.9e-08 34.3 4.5 3.5 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Mur_ligase_C PF02875.21 KFM74106.1 - 6.2e-05 23.2 0.0 0.00026 21.2 0.0 2.1 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain HTH_Tnp_Tc3_2 PF01498.18 KFM74107.1 - 2.2e-16 59.8 2.2 4e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74107.1 - 3.1e-13 49.7 0.0 5e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74108.1 - 4.5e-09 36.4 0.5 7.2e-09 35.8 0.5 1.4 1 0 0 1 1 1 1 Transposase fn3 PF00041.21 KFM74109.1 - 2e-45 153.0 16.4 1.7e-12 47.5 0.3 7.9 7 0 0 7 7 7 5 Fibronectin type III domain Ig_3 PF13927.6 KFM74109.1 - 0.00014 22.4 0.1 0.0036 17.9 0.0 3.7 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFM74109.1 - 0.00028 21.0 0.0 0.0012 18.9 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM74109.1 - 0.00049 20.2 0.0 0.00049 20.2 0.0 3.9 5 0 0 5 5 5 1 Immunoglobulin V-set domain EpoR_lig-bind PF09067.10 KFM74109.1 - 0.0026 17.9 1.5 0.046 13.9 0.2 3.6 4 1 0 4 4 4 1 Erythropoietin receptor, ligand binding Ig_2 PF13895.6 KFM74109.1 - 0.0027 18.0 1.7 0.078 13.3 0.1 3.5 2 0 0 2 2 2 1 Immunoglobulin domain IL6Ra-bind PF09240.10 KFM74109.1 - 0.0029 18.0 0.2 0.016 15.6 0.2 2.4 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding Interfer-bind PF09294.10 KFM74109.1 - 0.0043 17.4 15.7 1.3 9.4 1.3 4.8 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III I-set PF07679.16 KFM74109.1 - 0.014 15.4 0.0 0.073 13.2 0.0 2.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Tissue_fac PF01108.17 KFM74109.1 - 0.034 14.0 0.3 0.034 14.0 0.3 4.5 4 0 0 4 4 4 0 Tissue factor Pur_ac_phosph_N PF16656.5 KFM74109.1 - 1.4 9.5 8.3 2 9.1 0.2 4.3 5 0 0 5 5 4 0 Purple acid Phosphatase, N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM74110.1 - 2.5e-16 59.7 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74110.1 - 9.9e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Adaptin_N PF01602.20 KFM74111.1 - 1.2e-117 393.7 11.1 1.6e-117 393.3 11.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KFM74111.1 - 3.3e-59 198.8 0.1 3.3e-59 198.8 0.1 2.2 2 0 0 2 2 2 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KFM74111.1 - 8.7e-57 190.6 0.0 1.9e-56 189.6 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KFM74111.1 - 7.2e-10 39.1 5.7 4.7e-06 26.7 0.1 3.8 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFM74111.1 - 1.9e-09 37.0 0.3 0.023 14.9 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KFM74111.1 - 2.3e-09 37.5 0.6 0.024 15.0 0.0 5.1 3 3 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 KFM74111.1 - 7.9e-08 32.6 0.5 0.3 11.6 0.0 5.4 5 0 0 5 5 5 2 HEAT-like repeat MMS19_N PF14500.6 KFM74111.1 - 9.1e-05 22.2 1.9 0.00026 20.7 0.1 2.6 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.23 KFM74111.1 - 0.0016 18.4 0.3 0.86 9.7 0.0 3.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 KFM74111.1 - 0.002 17.6 4.3 1.1 8.6 0.3 3.1 1 1 2 3 3 3 2 Family of unknown function (DUF5578) Izumo-Ig PF16706.5 KFM74111.1 - 0.13 12.3 0.1 0.53 10.4 0.1 2.0 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain DUF3437 PF11919.8 KFM74111.1 - 0.16 11.9 0.0 0.53 10.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) HLH PF00010.26 KFM74112.1 - 7.5e-19 67.4 0.6 1.2e-18 66.8 0.6 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ARTD15_N PF18084.1 KFM74112.1 - 0.041 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 ARTD15 N-terminal domain MREG PF15812.5 KFM74112.1 - 0.1 12.9 0.9 0.41 10.9 0.1 2.0 2 0 0 2 2 2 0 Melanoregulin HTH_Tnp_Tc3_2 PF01498.18 KFM74113.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74113.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_1 PF11427.8 KFM74115.1 - 0.00068 19.4 0.1 0.0012 18.6 0.0 1.5 2 0 0 2 2 2 1 Tc3 transposase HTH_38 PF13936.6 KFM74115.1 - 0.0039 16.9 0.3 0.0039 16.9 0.3 2.5 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74115.1 - 0.0056 16.5 5.1 0.012 15.4 3.4 2.3 2 1 0 2 2 2 1 Homeodomain-like domain MRP-S34 PF16053.5 KFM74115.1 - 0.074 12.7 0.8 0.096 12.4 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 FeoC PF09012.10 KFM74115.1 - 0.078 13.1 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator LRR_8 PF13855.6 KFM74116.1 - 1.8e-27 94.9 5.4 6e-14 51.5 0.6 3.4 3 0 0 3 3 3 3 Leucine rich repeat I-set PF07679.16 KFM74116.1 - 1.5e-17 63.5 0.1 2.9e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM74116.1 - 1.4e-15 57.6 0.1 3.3e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_4 PF12799.7 KFM74116.1 - 4.6e-14 52.3 5.5 0.00014 22.2 0.3 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 KFM74116.1 - 4e-12 46.3 0.1 1e-11 45.0 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFM74116.1 - 2.5e-09 36.4 2.2 1.2 10.0 0.1 6.5 6 0 0 6 6 6 1 Leucine Rich Repeat ig PF00047.25 KFM74116.1 - 3.7e-08 33.4 0.2 3.7e-08 33.4 0.2 1.9 2 0 0 2 2 1 1 Immunoglobulin domain LRR_5 PF13306.6 KFM74116.1 - 2.3e-06 27.6 0.0 7.7e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) V-set PF07686.17 KFM74116.1 - 2.4e-05 24.5 0.8 6e-05 23.2 0.1 2.1 2 1 0 2 2 2 1 Immunoglobulin V-set domain Herpes_gE PF02480.16 KFM74116.1 - 0.0012 17.7 1.1 0.024 13.4 1.0 2.1 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E LRR_9 PF14580.6 KFM74116.1 - 0.0059 16.1 0.6 0.69 9.4 0.0 2.3 1 1 1 2 2 2 1 Leucine-rich repeat CD34_antigen PF06365.12 KFM74116.1 - 0.0063 16.1 0.2 0.01 15.4 0.2 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Amnionless PF14828.6 KFM74116.1 - 0.016 14.0 0.1 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Amnionless TMEM51 PF15345.6 KFM74116.1 - 0.028 14.3 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 LRR_6 PF13516.6 KFM74116.1 - 0.041 14.0 9.4 6.6 7.1 0.2 5.2 5 0 0 5 5 5 0 Leucine Rich repeat EphA2_TM PF14575.6 KFM74116.1 - 0.07 14.0 0.1 0.16 12.9 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TraL PF07178.11 KFM74116.1 - 0.076 13.5 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 TraL protein DUF4448 PF14610.6 KFM74116.1 - 0.08 12.7 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ig_6 PF18452.1 KFM74116.1 - 0.082 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Adeno_E3_CR2 PF02439.15 KFM74116.1 - 0.083 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Transposase_1 PF01359.18 KFM74117.1 - 7.3e-14 51.4 0.4 1.6e-13 50.3 0.1 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM74117.1 - 5.6e-10 39.2 0.0 9.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_24 PF13412.6 KFM74117.1 - 0.0059 16.1 0.1 0.035 13.7 0.0 2.3 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding rve PF00665.26 KFM74117.1 - 0.049 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain HTH_10 PF04967.12 KFM74117.1 - 0.091 12.6 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain ParB PF08775.10 KFM74117.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 ParB family DUF937 PF06078.11 KFM74117.1 - 0.22 12.1 0.1 0.37 11.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) HTH_32 PF13565.6 KFM74117.1 - 0.84 10.3 6.8 0.52 11.0 1.4 3.1 2 1 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 KFM74117.1 - 1.8 8.6 4.3 47 4.1 0.2 3.4 3 0 0 3 3 3 0 Winged helix-turn helix Bcl-2 PF00452.19 KFM74118.1 - 5.5e-16 59.1 0.1 9.3e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family HTH_38 PF13936.6 KFM74119.1 - 0.0001 22.0 0.2 0.0001 22.0 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Aa_trans PF01490.18 KFM74120.1 - 0.00037 19.3 2.2 0.00051 18.9 2.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 KFM74120.1 - 0.018 15.5 0.2 0.028 14.9 0.2 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein DUF2371 PF10177.9 KFM74120.1 - 0.03 14.5 0.1 0.12 12.5 0.1 2.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF4064 PF13273.6 KFM74120.1 - 0.2 11.9 3.0 0.52 10.6 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) AtuA PF07287.11 KFM74120.1 - 1.1 7.9 3.9 1.8 7.2 3.9 1.2 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA Aa_trans PF01490.18 KFM74121.1 - 6.7e-25 87.6 11.5 7.9e-25 87.4 11.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM74121.1 - 9e-07 28.3 11.1 1.2e-06 27.9 11.1 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF2684 PF10885.8 KFM74121.1 - 0.096 12.8 0.8 0.23 11.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) T4SS_CagC PF16943.5 KFM74121.1 - 0.12 12.5 2.3 6.2 7.0 0.0 2.7 3 0 0 3 3 3 0 Cag pathogenicity island, type IV secretory system D123 PF07065.14 KFM74122.1 - 2e-101 339.2 0.1 2.4e-101 338.9 0.1 1.1 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 KFM74122.1 - 0.00091 19.3 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 KFM74122.1 - 0.0068 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 Ig_5 PF16681.5 KFM74122.1 - 0.057 13.8 1.2 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Cast PF10174.9 KFM74124.1 - 5.5e-71 239.9 112.5 3.3e-58 197.6 90.3 3.0 1 1 1 3 3 3 3 RIM-binding protein of the cytomatrix active zone AAA_13 PF13166.6 KFM74124.1 - 0.0011 17.7 32.9 0.0011 17.7 32.9 3.8 2 2 1 3 3 3 1 AAA domain Cep57_MT_bd PF06657.13 KFM74124.1 - 0.0058 17.0 9.0 0.0058 17.0 9.0 9.4 4 2 5 10 10 10 1 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 KFM74124.1 - 0.076 13.2 109.1 0.06 13.6 19.3 5.9 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KFM74124.1 - 0.11 11.9 78.0 0.18 11.1 15.9 4.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KFM74124.1 - 0.22 10.4 112.3 0.14 11.0 29.4 5.4 1 1 4 5 5 5 0 Spc7 kinetochore protein DUF3584 PF12128.8 KFM74124.1 - 1.7 6.0 102.8 3.4 5.1 58.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) HOOK PF05622.12 KFM74124.1 - 7.7 4.5 117.7 0.049 11.8 23.0 5.9 1 1 5 6 6 6 0 HOOK protein GPHR_N PF12537.8 KFM74124.1 - 9.1 6.5 8.6 23 5.2 0.8 4.6 2 1 1 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal Cast PF10174.9 KFM74126.1 - 9.9e-22 77.0 2.4 1.2e-21 76.7 2.4 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone SPX PF03105.19 KFM74126.1 - 0.033 14.1 4.1 0.047 13.6 4.1 1.2 1 0 0 1 1 1 0 SPX domain KELK PF15796.5 KFM74126.1 - 0.066 13.7 2.1 0.11 12.9 2.1 1.4 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DDE_3 PF13358.6 KFM74127.1 - 5.4e-08 32.7 0.0 6.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PhetRS_B1 PF18262.1 KFM74127.1 - 0.17 12.1 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain zf-H2C2_2 PF13465.6 KFM74128.1 - 2.7e-42 141.3 46.0 2.6e-08 33.9 0.4 8.3 7 1 1 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74128.1 - 1.1e-29 101.2 64.1 2.8e-05 24.3 3.7 8.0 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74128.1 - 1.8e-23 81.2 59.7 0.00011 22.8 0.5 8.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM74128.1 - 2.6e-12 46.2 30.6 0.025 14.4 0.3 7.2 7 0 0 7 7 7 6 C2H2-type zinc-finger domain zf-met PF12874.7 KFM74128.1 - 2.8e-09 37.1 50.0 0.02 15.3 0.8 7.4 7 0 0 7 7 7 5 Zinc-finger of C2H2 type GAGA PF09237.11 KFM74128.1 - 2.5e-08 33.6 16.6 0.031 14.1 0.2 5.3 2 1 2 5 5 5 4 GAGA factor zf-C2H2_6 PF13912.6 KFM74128.1 - 4.7e-05 23.3 42.1 0.011 15.7 1.6 6.7 6 0 0 6 6 6 3 C2H2-type zinc finger BolA PF01722.18 KFM74128.1 - 0.00076 19.7 9.2 0.3 11.4 0.1 4.9 1 1 4 5 5 5 1 BolA-like protein zf-C2HC_2 PF13913.6 KFM74128.1 - 0.012 15.5 16.6 1.4 8.9 0.2 6.0 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFM74128.1 - 0.044 14.1 43.3 0.12 12.6 0.1 7.4 7 0 0 7 7 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM74128.1 - 0.1 12.5 26.6 1.6 8.6 0.1 6.8 1 1 6 7 7 7 0 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 KFM74128.1 - 0.11 12.5 18.1 6.8 6.8 1.8 4.4 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-DBF PF07535.12 KFM74128.1 - 0.33 11.1 30.1 4.2 7.6 0.1 6.3 6 0 0 6 6 6 0 DBF zinc finger zf_UBZ PF18439.1 KFM74128.1 - 0.56 9.8 0.1 0.56 9.8 0.1 5.6 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM74128.1 - 0.58 9.8 31.9 1.6 8.4 0.3 6.1 3 1 3 6 6 6 0 MYST family zinc finger domain C1_1 PF00130.22 KFM74128.1 - 2 8.3 38.9 1.5 8.8 6.5 5.0 3 2 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RVT PF13966.6 KFM74129.1 - 0.081 13.7 1.3 0.13 13.0 0.5 1.8 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KFM74130.1 - 1e-11 44.8 0.0 1e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2512 PF10710.9 KFM74132.1 - 0.23 11.1 2.1 0.29 10.8 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) HTH_Tnp_Tc3_2 PF01498.18 KFM74133.1 - 1.9e-16 60.1 2.2 4.5e-16 58.9 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74133.1 - 9.7e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Syntaxin-5_N PF11416.8 KFM74134.1 - 5.2e-07 28.7 0.0 1.8e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KFM74134.1 - 8.1e-06 25.6 12.7 0.0056 16.4 1.5 2.2 2 0 0 2 2 2 2 Syntaxin DUF5063 PF16702.5 KFM74134.1 - 0.023 15.1 1.6 0.3 11.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) NPC1_N PF16414.5 KFM74134.1 - 0.026 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus UPF0242 PF06785.11 KFM74134.1 - 0.028 14.5 11.2 0.096 12.8 3.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TRPM_tetra PF16519.5 KFM74134.1 - 0.12 12.5 2.6 0.15 12.2 0.3 2.3 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF16 PF01519.16 KFM74134.1 - 0.37 11.3 12.2 0.41 11.1 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 Spectrin PF00435.21 KFM74134.1 - 0.45 11.0 10.9 0.75 10.3 1.0 3.1 2 1 0 2 2 2 0 Spectrin repeat DUF4094 PF13334.6 KFM74134.1 - 0.68 10.4 3.4 1.7 9.1 0.2 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) MCPsignal PF00015.21 KFM74134.1 - 3.3 7.5 8.9 0.36 10.6 2.7 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SKA1 PF07160.12 KFM74134.1 - 3.8 7.3 12.5 4.4 7.1 2.0 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 APG6_N PF17675.1 KFM74134.1 - 4.4 7.8 7.7 4.1 7.9 0.8 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region KxDL PF10241.9 KFM74134.1 - 4.9 7.5 13.7 6.6 7.1 0.1 3.7 3 1 0 3 3 3 0 Uncharacterized conserved protein adh_short PF00106.25 KFM74135.1 - 1.3e-34 119.4 1.1 1.5e-34 119.2 1.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM74135.1 - 2e-25 89.8 0.2 2.2e-25 89.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM74135.1 - 2.1e-11 44.1 0.4 2.5e-11 43.8 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM74135.1 - 5.7e-06 26.0 0.1 7.2e-06 25.6 0.1 1.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM74135.1 - 0.00013 21.4 0.0 0.00026 20.5 0.0 1.4 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFM74135.1 - 0.0003 20.7 0.1 0.00036 20.5 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFM74135.1 - 0.0094 15.1 0.4 0.011 14.9 0.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TSCPD PF12637.7 KFM74135.1 - 0.011 16.0 1.0 0.011 16.0 1.0 1.9 2 0 0 2 2 2 0 TSCPD domain 3Beta_HSD PF01073.19 KFM74135.1 - 0.013 14.6 0.2 0.014 14.4 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KFM74135.1 - 0.021 15.4 0.2 0.035 14.7 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 KFM74135.1 - 0.029 13.7 0.6 0.046 13.0 0.6 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KFM74135.1 - 0.059 12.5 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF5354 PF17305.2 KFM74135.1 - 0.085 13.1 0.4 0.48 10.7 0.4 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5354) FIBP PF05427.11 KFM74135.1 - 0.093 12.0 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) adh_short PF00106.25 KFM74136.1 - 7.8e-49 165.8 0.1 9.5e-49 165.5 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM74136.1 - 2.9e-37 128.5 0.1 3.3e-37 128.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM74136.1 - 7.5e-11 42.3 0.1 1e-10 41.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM74136.1 - 2.3e-05 24.0 0.0 4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFM74136.1 - 0.00031 20.7 0.0 0.00035 20.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFM74136.1 - 0.0018 17.8 0.0 0.0044 16.5 0.0 1.5 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFM74136.1 - 0.0047 16.1 0.1 0.008 15.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFM74136.1 - 0.0052 15.8 0.0 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFM74136.1 - 0.0072 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF5354 PF17305.2 KFM74136.1 - 0.064 13.5 0.9 0.42 10.8 0.4 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5354) F420_oxidored PF03807.17 KFM74136.1 - 0.099 13.2 0.1 0.6 10.7 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.8 KFM74136.1 - 0.91 9.3 3.4 14 5.5 0.6 2.9 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HTH_Tnp_Tc3_2 PF01498.18 KFM74137.1 - 4.8e-16 58.8 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74137.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74137.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74137.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM74137.1 - 0.029 14.5 0.4 0.089 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM74137.1 - 2.3 8.9 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain GCFC PF07842.12 KFM74139.1 - 1.1e-18 67.9 0.7 4.8e-18 65.7 0.2 2.4 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein DUF1664 PF07889.12 KFM74139.1 - 0.11 12.5 2.0 0.28 11.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ldl_recept_a PF00057.18 KFM74140.1 - 1.2e-07 31.8 9.6 1.2e-07 31.8 9.6 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Syndecan PF01034.20 KFM74140.1 - 0.28 11.1 2.7 0.54 10.2 2.7 1.3 1 0 0 1 1 1 0 Syndecan domain Cation_ATPase_C PF00689.21 KFM74141.1 - 5.3e-41 140.3 5.7 5.3e-41 140.3 5.7 2.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFM74141.1 - 1.2e-35 122.7 15.7 1.9e-27 96.0 1.0 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 KFM74141.1 - 1.3e-19 70.0 0.0 3e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFM74141.1 - 3.8e-16 58.5 0.0 8e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus ATP_Ca_trans_C PF12424.8 KFM74141.1 - 2.6e-15 56.6 0.5 1.2e-14 54.5 0.5 2.3 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.26 KFM74141.1 - 3e-14 53.8 0.7 1.8e-12 48.0 0.7 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM74141.1 - 4.4e-08 33.2 1.5 2.2e-05 24.3 0.4 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase ATG22 PF11700.8 KFM74141.1 - 0.012 14.3 0.4 0.05 12.2 0.0 2.1 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like tRNA_synt_1c_R2 PF04557.15 KFM74141.1 - 0.063 14.2 2.1 0.2 12.6 2.1 1.8 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 tRNA-synt_1 PF00133.22 KFM74142.1 - 8.3e-189 628.7 0.3 5.1e-188 626.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFM74142.1 - 6.6e-27 94.3 0.0 8.4e-26 90.7 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFM74142.1 - 6.6e-08 31.7 0.2 0.018 13.8 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KFM74142.1 - 0.0017 17.7 0.0 0.012 15.0 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DASH_Hsk3 PF08227.11 KFM74143.1 - 0.012 15.9 2.3 12 6.4 0.0 3.6 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like MbeD_MobD PF04899.12 KFM74143.1 - 0.042 14.0 9.8 0.054 13.6 0.6 3.6 3 2 0 3 3 3 0 MbeD/MobD like ETC_C1_NDUFA4 PF04800.12 KFM74143.1 - 0.13 12.5 0.7 12 6.2 0.1 2.6 2 0 0 2 2 2 0 ETC complex I subunit conserved region SlyX PF04102.12 KFM74143.1 - 0.18 12.5 5.4 22 5.7 0.4 3.6 3 0 0 3 3 3 0 SlyX DUF4140 PF13600.6 KFM74143.1 - 0.21 12.1 1.8 1.4 9.4 0.3 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Syntaxin PF00804.25 KFM74143.1 - 0.23 11.1 12.9 0.1 12.2 8.7 2.2 1 1 2 3 3 3 0 Syntaxin PI3K_P85_iSH2 PF16454.5 KFM74143.1 - 0.4 10.3 16.0 7.6 6.1 0.1 3.4 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DivIC PF04977.15 KFM74143.1 - 1.6 8.6 6.1 4.4 7.2 2.0 2.9 2 0 0 2 2 2 0 Septum formation initiator SKA2 PF16740.5 KFM74143.1 - 3 7.7 12.3 0.67 9.8 3.8 3.3 1 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 NPV_P10 PF05531.12 KFM74143.1 - 5.7 7.5 8.6 4.5 7.8 0.5 3.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Lipocalin_2 PF08212.12 KFM74144.1 - 0.0011 18.9 0.1 0.0014 18.6 0.1 1.3 1 1 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 KFM74144.1 - 0.0079 16.4 0.0 0.013 15.7 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PX PF00787.24 KFM74144.1 - 0.09 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 PX domain WD40 PF00400.32 KFM74145.1 - 3.4e-14 53.0 0.8 1.1e-06 29.2 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM74145.1 - 0.0016 18.7 0.0 0.0042 17.4 0.0 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM74145.1 - 0.014 14.4 0.3 3.5 6.5 0.2 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Zn_ribbon_17 PF17120.5 KFM74147.1 - 4e-08 32.8 17.1 4e-08 32.8 17.1 1.5 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 KFM74147.1 - 0.00016 21.9 3.7 0.00016 21.9 3.7 1.9 1 1 1 2 2 2 1 Zinc-ribbon like family MCR PF18509.1 KFM74147.1 - 0.24 11.0 7.8 0.82 9.3 7.8 1.9 1 1 0 1 1 1 0 Magnetochrome domain zf-4CXXC_R1 PF10497.9 KFM74147.1 - 3.3 8.0 15.8 3.1 8.1 10.3 2.0 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 HTH_Tnp_Tc3_2 PF01498.18 KFM74148.1 - 6.8e-16 58.3 0.8 1.5e-15 57.1 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74148.1 - 2.4e-09 37.1 0.0 3.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MarR_2 PF12802.7 KFM74148.1 - 0.0023 17.8 0.2 0.064 13.1 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_32 PF13565.6 KFM74148.1 - 0.0055 17.3 1.1 0.0055 17.3 1.1 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_3 PF01381.22 KFM74148.1 - 0.0098 15.9 0.4 0.033 14.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM74148.1 - 0.024 14.6 0.5 0.055 13.4 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain PAX PF00292.18 KFM74148.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 'Paired box' domain HTH_23 PF13384.6 KFM74148.1 - 0.056 13.2 0.1 0.27 11.1 0.1 2.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KFM74148.1 - 0.092 12.9 1.1 0.23 11.6 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KFM74148.1 - 0.12 11.9 1.0 0.91 9.1 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding FMO-like PF00743.19 KFM74149.1 - 6.6e-81 272.3 0.0 7.6e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM74149.1 - 0.014 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Inos-1-P_synth PF01658.17 KFM74149.1 - 0.087 13.1 0.1 0.9 9.8 0.0 2.2 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase FMO-like PF00743.19 KFM74150.1 - 2.1e-42 145.3 1.3 2.4e-42 145.1 1.3 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM74150.1 - 3e-09 36.6 0.1 4.1e-09 36.1 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM74150.1 - 0.00016 20.9 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KFM74150.1 - 0.0036 16.6 0.0 0.0037 16.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFM74151.1 - 1e-167 558.8 0.0 1.2e-167 558.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM74151.1 - 1.2e-19 70.7 0.0 8.9e-14 51.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM74151.1 - 7.4e-15 54.9 0.0 1.2e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM74151.1 - 2.2e-09 36.9 0.0 1.8e-05 24.1 0.0 3.5 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFM74151.1 - 6e-05 23.5 0.5 0.054 14.1 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM74151.1 - 0.00015 21.9 0.1 0.001 19.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KFM74151.1 - 0.012 14.9 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KFM74151.1 - 0.014 15.0 0.1 12 5.4 0.0 3.3 3 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM74151.1 - 0.045 12.8 0.0 5.1 6.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KFM74151.1 - 0.058 12.6 0.0 0.73 9.0 0.0 2.2 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KFM74151.1 - 0.12 11.4 0.2 1.3 8.0 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KFM74151.1 - 0.24 11.4 1.5 28 4.7 0.0 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding FMO-like PF00743.19 KFM74152.1 - 1.4e-185 617.8 0.4 1.6e-185 617.5 0.4 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM74152.1 - 6.9e-21 74.8 0.2 1.4e-16 60.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM74152.1 - 1.3e-13 50.8 0.0 8.4e-11 41.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM74152.1 - 1.3e-09 37.7 0.5 9.4e-07 28.3 0.1 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFM74152.1 - 6e-05 23.5 0.5 0.14 12.7 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM74152.1 - 0.00021 20.6 0.1 0.083 12.1 0.1 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KFM74152.1 - 0.00041 20.5 0.1 0.0017 18.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFM74152.1 - 0.011 15.7 2.0 0.44 10.5 0.1 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding Peptidase_M17_N PF02789.17 KFM74152.1 - 0.025 14.4 0.1 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain HI0933_like PF03486.14 KFM74152.1 - 0.03 13.0 1.2 4.7 5.8 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 KFM74152.1 - 0.034 13.7 0.2 16 4.9 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFM74152.1 - 0.055 12.7 0.8 0.53 9.5 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 KFM74152.1 - 0.067 13.3 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KFM74152.1 - 0.22 10.8 0.3 8.9 5.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KFM74152.1 - 1.2 8.2 3.0 2.4 7.1 0.2 2.7 3 1 1 4 4 4 0 Glucose inhibited division protein A DDE_3 PF13358.6 KFM74153.1 - 1.6e-15 57.1 0.0 3e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74153.1 - 1.9e-13 50.5 0.4 4.1e-13 49.4 0.1 1.7 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 KFM74153.1 - 7.1e-06 26.1 1.6 6.3e-05 23.0 0.1 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain PAX PF00292.18 KFM74153.1 - 0.00015 21.7 0.1 0.00029 20.7 0.1 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 KFM74153.1 - 0.00082 19.9 1.2 0.00082 19.9 1.2 2.6 2 1 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM74153.1 - 0.012 15.5 0.3 0.24 11.3 0.0 2.7 2 0 0 2 2 2 0 MarR family HTH_37 PF13744.6 KFM74153.1 - 0.061 13.3 0.0 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM74153.1 - 0.063 13.1 2.8 0.24 11.2 0.0 3.1 4 0 0 4 4 4 0 Homeodomain-like domain DUF5447 PF17525.2 KFM74153.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5447) FMO-like PF00743.19 KFM74154.1 - 5.5e-165 549.8 0.1 7e-165 549.4 0.1 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM74154.1 - 6.1e-17 61.8 0.3 1.1e-11 44.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM74154.1 - 2e-12 47.0 0.0 2.3e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM74154.1 - 1.2e-11 44.3 0.0 6e-08 32.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFM74154.1 - 4.2e-08 33.3 0.1 2.5e-06 27.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFM74154.1 - 1.4e-06 28.7 1.0 0.0069 16.9 0.1 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM74154.1 - 0.00011 21.6 0.1 0.023 14.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KFM74154.1 - 0.00012 21.4 0.8 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFM74154.1 - 0.00081 18.7 0.2 0.0099 15.2 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KFM74154.1 - 0.0014 18.6 0.2 0.1 12.6 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KFM74154.1 - 0.011 15.3 0.0 2.5 7.6 0.1 3.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.22 KFM74154.1 - 0.018 14.2 0.7 3.4 6.6 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 KFM74154.1 - 0.019 13.7 2.0 0.15 10.7 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.20 KFM74154.1 - 0.027 14.5 0.3 5.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KFM74154.1 - 0.034 14.6 0.0 5.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFM74154.1 - 0.059 12.7 0.1 9.5 5.5 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_10 PF05971.12 KFM74154.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase DNA_pol_viral_N PF00242.17 KFM74154.1 - 0.21 11.0 0.1 0.37 10.2 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM74155.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74155.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74155.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74155.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74155.1 - 2 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM74156.1 - 4.7e-16 58.8 3.5 6.1e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74156.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74156.1 - 3e-07 30.1 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74156.1 - 0.0028 17.4 0.6 0.008 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74156.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_4 PF13359.6 KFM74160.1 - 2e-32 112.0 0.0 4.2e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM74160.1 - 2.2e-11 43.8 0.0 3.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFM74160.1 - 1.2e-05 25.0 0.0 0.00058 19.6 0.0 2.3 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 KFM74160.1 - 0.018 14.8 0.0 0.054 13.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.6 KFM74161.1 - 1.2e-15 57.7 0.1 1.4e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM74161.1 - 0.0023 18.2 0.1 0.0033 17.7 0.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF573 PF04504.14 KFM74161.1 - 0.01 16.5 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF573 NADH_B2 PF14813.6 KFM74161.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Myb_DNA-bind_3 PF12776.7 KFM74161.1 - 0.031 15.3 0.0 0.043 14.8 0.0 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_1 PF03184.19 KFM74162.1 - 2.6e-07 30.5 0.1 3.3e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM74163.1 - 1.1e-90 294.4 93.4 7.9e-09 35.6 1.1 14.2 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74163.1 - 2.2e-59 194.7 105.7 3.9e-06 27.0 0.3 13.2 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74163.1 - 1e-43 144.2 100.9 0.00079 20.1 1.3 13.2 13 0 0 13 13 13 12 C2H2-type zinc finger zf-met PF12874.7 KFM74163.1 - 2e-35 120.2 82.7 0.0008 19.7 1.9 12.6 12 0 0 12 12 12 12 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74163.1 - 2.8e-22 78.2 77.5 0.0055 16.7 0.7 12.5 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74163.1 - 1.9e-18 66.2 54.7 0.068 13.5 0.2 12.2 12 0 0 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM74163.1 - 4e-15 55.2 59.1 0.025 14.3 0.4 12.9 13 0 0 13 13 13 7 C2H2-type zinc-finger domain GAGA PF09237.11 KFM74163.1 - 2.8e-09 36.6 22.9 0.00022 21.0 0.9 8.0 4 3 4 8 8 8 3 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM74163.1 - 3.3e-07 30.2 37.0 1.2 9.2 0.1 11.2 9 2 3 12 12 12 3 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM74163.1 - 3.8e-07 30.0 30.6 1.3 9.1 1.3 8.1 4 3 2 6 6 6 3 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM74163.1 - 6.8e-06 25.8 46.9 1.5 8.8 0.1 11.5 11 0 0 11 11 11 4 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFM74163.1 - 7.4e-06 26.2 71.7 0.58 10.5 0.9 11.2 1 1 9 10 10 10 4 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFM74163.1 - 5.6e-05 22.9 59.6 0.27 11.2 1.6 10.3 5 3 5 10 10 10 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-DBF PF07535.12 KFM74163.1 - 0.00013 22.0 47.9 10 6.3 0.1 11.6 12 0 0 12 12 11 0 DBF zinc finger BolA PF01722.18 KFM74163.1 - 0.00017 21.8 14.4 4.4 7.7 0.9 6.8 2 1 2 5 5 5 1 BolA-like protein zf-C2H2_9 PF16293.5 KFM74163.1 - 0.00046 20.0 41.9 6.2 6.8 0.2 11.5 6 4 6 12 12 12 1 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM74163.1 - 0.0034 17.5 39.7 0.075 13.1 4.1 5.2 1 1 3 4 4 4 2 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM74163.1 - 0.0039 17.3 43.2 26 5.1 0.3 11.7 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 KFM74163.1 - 0.018 14.7 45.6 2.2 7.9 0.1 11.3 12 0 0 12 12 12 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM74163.1 - 0.018 15.1 38.7 1.1 9.5 1.5 7.6 6 1 1 7 7 7 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFM74163.1 - 0.019 14.7 67.5 0.084 12.7 0.7 10.9 12 0 0 12 12 12 0 zinc-finger C2H2-type zf-MYST PF17772.1 KFM74163.1 - 0.033 13.8 56.3 2 8.1 0.3 11.7 4 4 8 12 12 12 0 MYST family zinc finger domain HNH_5 PF14279.6 KFM74163.1 - 0.55 10.1 42.7 5.3 7.0 0.1 10.1 10 2 0 10 10 10 0 HNH endonuclease zinc_ribbon_15 PF17032.5 KFM74163.1 - 1.3 9.8 43.0 14 6.5 1.6 6.7 1 1 8 9 9 9 0 zinc-ribbon family FadR_C PF07840.12 KFM74164.1 - 0.042 13.8 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 FadR C-terminal domain PLDc_2 PF13091.6 KFM74166.1 - 4.6e-27 94.5 0.1 6.3e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 KFM74166.1 - 0.00071 19.6 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 Phospholipase D Active site motif FAM83 PF07894.12 KFM74166.1 - 0.089 12.3 0.3 0.17 11.4 0.3 1.6 1 1 0 1 1 1 0 FAM83 A-H WD40 PF00400.32 KFM74167.1 - 3.9e-26 90.8 0.3 0.0026 18.6 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 KFM74167.1 - 0.00018 21.5 0.7 0.027 14.3 0.0 3.4 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFM74167.1 - 0.00022 21.5 0.0 8.1 6.8 0.0 5.0 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM74167.1 - 0.0019 17.2 0.0 0.82 8.6 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFM74167.1 - 0.0062 15.2 0.2 0.053 12.2 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_3 PF15911.5 KFM74167.1 - 0.038 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF3821 PF12863.7 KFM74167.1 - 0.1 12.5 0.3 1.8 8.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3821) Fe_hyd_lg_C PF02906.14 KFM74168.1 - 1.6e-54 185.1 0.0 2.3e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain COR PF16095.5 KFM74168.1 - 0.0051 16.7 0.0 0.046 13.5 0.0 2.1 1 1 1 2 2 2 1 C-terminal of Roc, COR, domain HTH_Tnp_Tc3_2 PF01498.18 KFM74169.1 - 2.4e-16 59.7 2.2 4.3e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74169.1 - 4.3e-13 49.3 0.0 6.8e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease GYF PF02213.16 KFM74170.1 - 4.7e-20 71.0 0.8 1.1e-19 69.8 0.8 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KFM74170.1 - 0.00076 19.2 0.1 0.0039 17.0 0.0 2.4 2 0 0 2 2 2 1 GYF domain 2 SPC12 PF06645.13 KFM74171.1 - 2.9e-19 68.9 3.4 3.4e-19 68.7 3.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3754 PF12576.8 KFM74171.1 - 0.058 13.4 0.0 0.064 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) DUF3040 PF11239.8 KFM74171.1 - 0.11 12.8 0.2 0.12 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Rep_fac-A_C PF08646.10 KFM74172.1 - 3.3e-49 166.4 9.1 2.2e-47 160.5 6.8 2.6 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KFM74172.1 - 1e-33 115.1 1.6 2.8e-33 113.7 1.6 1.8 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KFM74172.1 - 5.2e-24 84.2 0.5 1.2e-22 79.8 0.3 2.5 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KFM74172.1 - 2.7e-12 46.5 0.1 7.9e-11 41.8 0.0 2.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KFM74172.1 - 1.9e-05 24.5 0.9 0.0065 16.2 0.4 2.2 2 0 0 2 2 2 2 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 KFM74172.1 - 0.016 15.5 0.6 0.038 14.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF223 Transposase_1 PF01359.18 KFM74173.1 - 2.2e-06 27.4 0.0 2.5e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_Tnp_Tc3_2 PF01498.18 KFM74175.1 - 4.1e-16 59.0 3.4 5.2e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74175.1 - 1.1e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74175.1 - 1.4e-07 31.1 1.2 6.6e-07 29.0 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74175.1 - 0.0019 17.9 0.6 0.007 16.1 0.6 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM74176.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74176.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74177.1 - 1e-14 54.5 1.0 2e-14 53.6 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74177.1 - 7.8e-14 51.7 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Glycos_transf_2 PF00535.26 KFM74179.1 - 7e-37 126.8 0.0 1.1e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFM74179.1 - 2.5e-29 102.1 3.4 3.8e-29 101.5 3.4 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KFM74179.1 - 4e-07 30.7 0.4 0.015 16.0 0.0 2.8 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Glyco_transf_7C PF02709.14 KFM74179.1 - 5.8e-06 25.9 0.1 1.4e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 KFM74179.1 - 7.9e-05 22.7 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFM74179.1 - 0.00043 19.8 0.0 0.0013 18.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 zf-CCHC PF00098.23 KFM74180.1 - 8.7e-11 41.4 8.9 8.5e-06 25.6 0.9 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFM74180.1 - 7.8e-09 35.2 10.0 1.9e-05 24.4 1.7 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KFM74180.1 - 8.3e-05 22.2 4.8 0.025 14.3 0.6 2.3 2 0 0 2 2 2 2 Zinc knuckle HscB_4_cys PF18256.1 KFM74180.1 - 0.011 15.5 10.6 0.35 10.7 1.7 2.6 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif DUF4407 PF14362.6 KFM74180.1 - 0.015 14.6 0.1 0.017 14.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mu-like_Com PF10122.9 KFM74180.1 - 0.025 14.0 3.4 0.037 13.5 0.4 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com HSBP1 PF06825.12 KFM74180.1 - 0.061 13.2 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 zf-C2H2_10 PF16588.5 KFM74180.1 - 0.26 11.1 9.1 1.3 8.8 0.6 2.3 2 0 0 2 2 2 0 C2H2 zinc-finger DUF2703 PF10865.8 KFM74180.1 - 0.49 10.6 3.9 2.1 8.5 0.1 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF2703) zf-FCS PF06467.14 KFM74180.1 - 0.76 9.8 8.9 2.2 8.3 1.5 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.6 KFM74180.1 - 1.4 8.5 6.9 0.39 10.2 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_2 PF13696.6 KFM74180.1 - 7.2 6.5 9.2 11 5.9 1.4 2.2 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 KFM74181.1 - 5.1e-44 150.4 0.2 6.8e-44 150.0 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sema PF01403.19 KFM74182.1 - 4e-45 154.4 0.2 5e-45 154.1 0.2 1.0 1 0 0 1 1 1 1 Sema domain BTB PF00651.31 KFM74183.1 - 3.8e-14 52.8 0.3 5.1e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 BTB/POZ domain An_peroxidase PF03098.15 KFM74184.1 - 1.2e-150 502.6 0.1 1.9e-150 502.0 0.1 1.3 1 0 0 1 1 1 1 Animal haem peroxidase LAMTOR PF15454.6 KFM74185.1 - 7.6e-09 36.1 0.0 3.1e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Methyltransf_11 PF08241.12 KFM74186.1 - 5e-14 52.7 0.0 1.2e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM74186.1 - 1.3e-13 51.1 0.0 1.8e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM74186.1 - 2.1e-13 50.8 0.0 2.3e-12 47.4 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM74186.1 - 1.6e-12 47.4 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM74186.1 - 1.7e-11 44.8 0.0 2.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM74186.1 - 1.9e-06 27.6 0.0 3.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KFM74186.1 - 5.8e-06 26.1 0.0 9.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KFM74186.1 - 7.6e-05 22.2 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KFM74186.1 - 0.0029 17.1 0.0 0.0053 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Pox_MCEL PF03291.16 KFM74186.1 - 0.0046 16.1 0.0 0.051 12.7 0.0 2.2 1 1 0 1 1 1 1 mRNA capping enzyme PCMT PF01135.19 KFM74186.1 - 0.0071 16.1 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rsm22 PF09243.10 KFM74186.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 HTH_Tnp_Tc3_2 PF01498.18 KFM74188.1 - 3.2e-14 52.9 1.0 6e-14 52.0 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74188.1 - 8.2e-14 51.6 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 KFM74188.1 - 2.6e-06 27.4 0.0 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM74188.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.18 KFM74189.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74189.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74189.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74189.1 - 0.0027 17.4 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74189.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Hormone_recep PF00104.30 KFM74191.1 - 2.2e-11 43.8 1.0 2.6e-11 43.5 1.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor IBV_3B PF03622.13 KFM74191.1 - 0.087 13.0 0.1 0.26 11.4 0.0 1.8 2 1 0 2 2 2 0 IBV 3B protein p450 PF00067.22 KFM74193.1 - 0.00053 18.8 0.0 0.0007 18.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PID_2 PF14719.6 KFM74194.1 - 2.1e-74 249.4 0.6 2.7e-74 249.0 0.6 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DUF3964 PF13107.6 KFM74195.1 - 0.065 13.6 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) adh_short PF00106.25 KFM74196.1 - 0.03 13.8 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.25 KFM74197.1 - 4e-07 29.7 0.2 7.5e-07 28.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 KFM74197.1 - 0.025 14.0 0.1 0.032 13.7 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KFM74197.1 - 0.08 12.8 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 KR domain p25-alpha PF05517.12 KFM74200.1 - 2.5e-08 34.2 0.0 3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 p25-alpha C2 PF00168.30 KFM74202.1 - 4.7e-14 52.5 0.0 8.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain zf-H2C2_2 PF13465.6 KFM74203.1 - 1e-91 297.6 90.2 1.6e-09 37.7 0.3 14.1 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74203.1 - 4.7e-51 168.5 123.2 2.5e-06 27.6 1.1 13.1 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74203.1 - 1.6e-36 121.8 116.8 0.0013 19.4 1.5 13.1 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM74203.1 - 9e-28 95.8 113.3 0.00023 21.5 1.5 13.2 13 0 0 13 13 13 12 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM74203.1 - 3.7e-18 64.9 71.3 0.052 13.3 0.0 13.6 13 0 0 13 13 13 9 C2H2-type zinc-finger domain BolA PF01722.18 KFM74203.1 - 1.2e-09 38.2 18.5 0.26 11.6 0.3 9.0 1 1 7 8 8 8 4 BolA-like protein zf-C2H2_jaz PF12171.8 KFM74203.1 - 6.7e-09 35.8 71.0 0.13 12.6 1.0 13.0 13 0 0 13 13 13 5 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM74203.1 - 1.2e-08 34.7 34.9 1.4 8.8 0.3 11.2 1 1 12 13 13 13 4 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM74203.1 - 6.6e-07 29.3 49.6 1.6 8.9 0.1 12.0 7 4 6 13 13 13 4 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM74203.1 - 0.00022 21.0 68.8 2.9 7.8 0.5 12.6 2 2 11 13 13 13 6 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM74203.1 - 0.0021 18.2 66.6 7.1 6.8 0.3 13.0 13 0 0 13 13 13 3 DBF zinc finger zf-C2H2_11 PF16622.5 KFM74203.1 - 0.0034 17.1 9.5 0.0091 15.7 2.6 12.8 13 0 0 13 13 13 3 zinc-finger C2H2-type BHD_1 PF10403.9 KFM74203.1 - 0.029 14.2 0.6 45 4.0 0.0 4.5 3 1 1 4 4 4 0 Rad4 beta-hairpin domain 1 zf-RRPl_C4 PF17026.5 KFM74203.1 - 0.03 14.4 55.9 1.3 9.1 8.3 5.2 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_6 PF13912.6 KFM74203.1 - 0.089 12.8 93.7 0.1 12.6 0.9 13.1 13 0 0 13 13 13 0 C2H2-type zinc finger C1_1 PF00130.22 KFM74203.1 - 0.17 11.8 76.8 0.2 11.6 1.8 9.8 2 2 7 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 KFM74203.1 - 3.6 7.8 74.3 2.9 8.1 10.1 7.2 2 2 3 5 5 4 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM74203.1 - 3.6 8.4 55.4 1.5 9.7 1.2 7.0 1 1 4 6 6 6 0 zinc-ribbon family ADK_lid PF05191.14 KFM74203.1 - 4 7.5 48.3 8 6.5 1.6 8.6 3 2 6 10 10 10 0 Adenylate kinase, active site lid Mga PF05043.13 KFM74203.1 - 8.6 7.0 7.4 50 4.6 0.1 4.4 2 1 3 5 5 5 0 Mga helix-turn-helix domain zf-H2C2_2 PF13465.6 KFM74204.1 - 5.5e-47 156.2 37.0 2.8e-08 33.8 0.2 7.6 8 0 0 8 8 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74204.1 - 1.6e-33 113.3 46.4 1e-05 25.7 0.2 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74204.1 - 1.3e-25 87.9 45.7 0.00023 21.7 0.2 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM74204.1 - 1.7e-16 60.0 40.5 0.0023 18.3 0.7 7.2 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM74204.1 - 1.2e-09 37.7 25.2 0.0095 15.7 0.0 6.5 6 0 0 6 6 6 5 C2H2-type zinc-finger domain BolA PF01722.18 KFM74204.1 - 1.9e-07 31.2 1.2 0.78 10.1 0.1 4.2 1 1 1 3 3 3 2 BolA-like protein GAGA PF09237.11 KFM74204.1 - 3.2e-07 30.0 9.3 0.12 12.2 0.0 5.5 1 1 4 6 6 6 2 GAGA factor zf-C2H2_jaz PF12171.8 KFM74204.1 - 3.8e-07 30.2 28.3 0.13 12.6 0.0 7.3 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM74204.1 - 2.1e-06 27.6 43.3 0.14 12.2 0.3 7.5 7 1 0 7 7 7 4 C2H2-type zinc finger zf-DBF PF07535.12 KFM74204.1 - 2e-05 24.6 20.1 1.6 8.9 0.5 6.4 6 0 0 6 6 6 1 DBF zinc finger zf-C2H2_9 PF16293.5 KFM74204.1 - 3.5e-05 23.6 18.7 0.47 10.3 0.1 6.0 2 1 4 6 6 6 1 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM74204.1 - 5.6e-05 23.1 15.1 0.95 9.6 0.0 6.1 5 1 1 6 6 6 1 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM74204.1 - 6.2e-05 22.5 25.2 0.86 9.3 0.1 6.1 1 1 5 6 6 6 3 MYST family zinc finger domain Prok-RING_1 PF14446.6 KFM74204.1 - 0.0022 17.9 19.9 4.4 7.3 0.1 6.7 7 0 0 7 7 7 1 Prokaryotic RING finger family 1 Complex1_49kDa PF00346.19 KFM74204.1 - 0.0047 16.1 0.2 1.3 8.1 0.0 2.9 1 1 2 3 3 3 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF4825 PF16107.5 KFM74204.1 - 0.021 14.9 0.1 19 5.4 0.0 3.7 1 1 4 5 5 5 0 Domain of unknown function (DUF4825) Tox-HNH-HHH PF15637.6 KFM74204.1 - 0.029 14.5 0.0 15 5.8 0.0 2.9 1 1 2 3 3 3 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_11 PF16622.5 KFM74204.1 - 0.046 13.5 0.2 0.046 13.5 0.2 5.7 6 0 0 6 6 6 0 zinc-finger C2H2-type Zf_RING PF16744.5 KFM74204.1 - 0.058 13.5 27.5 14 5.9 0.1 6.7 1 1 5 6 6 6 0 KIAA1045 RING finger C1_4 PF07975.12 KFM74204.1 - 0.06 13.6 28.8 0.39 11.0 1.4 4.7 1 1 3 5 5 4 0 TFIIH C1-like domain ADK_lid PF05191.14 KFM74204.1 - 0.12 12.4 0.3 0.12 12.4 0.3 4.6 1 1 6 7 7 7 0 Adenylate kinase, active site lid zf-RRPl_C4 PF17026.5 KFM74204.1 - 0.18 12.0 19.7 1.2 9.3 5.4 3.2 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-FCS PF06467.14 KFM74204.1 - 0.2 11.6 22.6 0.4 10.7 0.6 6.0 4 2 2 6 6 6 0 MYM-type Zinc finger with FCS sequence motif C5HCH PF17982.1 KFM74204.1 - 0.25 11.5 26.4 11 6.3 0.6 6.6 3 2 4 7 7 7 0 NSD Cys-His rich domain DUF4764 PF15961.5 KFM74204.1 - 0.27 9.9 13.9 3.1 6.4 0.3 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4764) zinc_ribbon_15 PF17032.5 KFM74204.1 - 0.35 11.6 21.2 1.9 9.3 1.2 3.9 1 1 3 5 5 5 0 zinc-ribbon family FYVE PF01363.21 KFM74204.1 - 0.4 10.9 28.5 18 5.6 9.7 4.4 1 1 2 3 3 3 0 FYVE zinc finger zf-RING_UBOX PF13445.6 KFM74204.1 - 0.48 10.5 10.9 31 4.7 0.1 5.7 6 1 1 7 7 6 0 RING-type zinc-finger zf-CHCC PF10276.9 KFM74204.1 - 0.55 10.3 6.8 22 5.2 0.0 4.4 5 0 0 5 5 4 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KFM74204.1 - 0.66 10.0 22.0 11 6.1 0.0 6.6 7 0 0 7 7 7 0 zinc-finger of a C2HC-type C1_1 PF00130.22 KFM74204.1 - 0.7 9.8 28.8 1.5 8.8 2.8 5.9 1 1 6 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_8 PF15909.5 KFM74204.1 - 0.73 10.2 22.0 0.37 11.1 2.8 3.5 1 1 3 4 4 4 0 C2H2-type zinc ribbon DUF2256 PF10013.9 KFM74204.1 - 0.9 9.7 23.0 31 4.8 0.1 6.3 7 0 0 7 7 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KFM74204.1 - 1.1 9.7 36.8 3.9 7.9 1.1 6.1 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM74204.1 - 1.2 8.8 23.7 4.1 7.1 0.1 6.4 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-Dof PF02701.15 KFM74204.1 - 1.5 9.0 18.1 1.4 9.2 1.1 5.4 1 1 4 5 5 5 0 Dof domain, zinc finger zf-UDP PF14569.6 KFM74204.1 - 1.7 8.8 15.0 4.9 7.3 2.8 4.0 1 1 3 5 5 5 0 Zinc-binding RING-finger TRAF6_Z2 PF18048.1 KFM74204.1 - 1.8 8.8 28.8 0.91 9.7 0.4 6.4 7 0 0 7 7 6 0 TNF receptor-associated factor 6 zinc finger 2 zf-FPG_IleRS PF06827.14 KFM74204.1 - 6.4 6.7 16.6 48 3.9 0.1 5.5 6 0 0 6 6 5 0 Zinc finger found in FPG and IleRS Arf PF00025.21 KFM74205.1 - 2e-58 196.7 0.0 2.5e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFM74205.1 - 1.7e-13 50.5 0.0 2.1e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM74205.1 - 4.8e-13 49.4 0.0 6.1e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFM74205.1 - 1.5e-12 47.3 0.0 2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFM74205.1 - 8.9e-05 21.8 0.0 0.00078 18.7 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFM74205.1 - 0.00014 21.9 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM74205.1 - 0.0016 17.8 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM74205.1 - 0.0081 15.7 0.0 0.021 14.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.18 KFM74205.1 - 0.025 13.9 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.17 KFM74205.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Microvir_J PF04726.13 KFM74205.1 - 0.083 12.9 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Microvirus J protein Yippee-Mis18 PF03226.14 KFM74206.1 - 2.9e-05 24.2 1.2 3.6e-05 23.9 1.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Jas PF16135.5 KFM74206.1 - 0.014 15.6 0.5 0.014 15.6 0.5 1.6 1 1 1 2 2 2 0 TPL-binding domain in jasmonate signalling ATPgrasp_YheCD PF14398.6 KFM74206.1 - 0.032 13.5 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 YheC/D like ATP-grasp Med15_fungi PF05397.12 KFM74207.1 - 0.055 13.7 0.1 0.057 13.7 0.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 15 CCDC92 PF14916.6 KFM74208.1 - 3.3e-12 46.0 3.7 3.3e-12 46.0 3.7 2.7 2 1 1 3 3 3 1 Coiled-coil domain of unknown function APP_E2 PF12925.7 KFM74208.1 - 0.0017 18.1 0.4 0.0029 17.3 0.4 1.4 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein Jnk-SapK_ap_N PF09744.9 KFM74208.1 - 0.0017 18.6 6.3 0.0035 17.6 6.3 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Lebercilin PF15619.6 KFM74208.1 - 0.12 12.0 9.9 0.26 10.9 9.4 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 KFM74208.1 - 0.14 11.6 9.8 0.7 9.3 5.2 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Nas2_N PF18265.1 KFM74208.1 - 0.36 10.8 5.0 0.22 11.4 0.2 3.0 4 0 0 4 4 4 0 Nas2 N_terminal domain NYD-SP28_assoc PF14775.6 KFM74208.1 - 0.54 10.4 5.2 7.7 6.7 0.8 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain HAP1_N PF04849.13 KFM74208.1 - 2.6 7.2 13.1 9.4 5.3 13.1 1.8 1 1 0 1 1 1 0 HAP1 N-terminal conserved region TMF_DNA_bd PF12329.8 KFM74208.1 - 4.1 7.5 14.8 0.29 11.2 5.0 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KFM74208.1 - 4.6 7.3 13.0 18 5.4 12.9 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 KFM74208.1 - 6.8 6.9 12.2 0.89 9.7 3.7 3.4 3 0 0 3 3 3 0 bZIP transcription factor DUF2207 PF09972.9 KFM74210.1 - 0.00068 18.5 0.1 0.00082 18.3 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) AAA_lid_9 PF17871.1 KFM74210.1 - 0.044 13.7 1.0 0.079 12.9 0.0 1.9 3 0 0 3 3 3 0 AAA lid domain DUF3139 PF11337.8 KFM74210.1 - 1.7 9.4 3.9 1.3 9.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) SNF PF00209.18 KFM74211.1 - 3.9e-100 336.0 30.9 1e-76 258.7 21.2 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family DUF962 PF06127.11 KFM74211.1 - 0.041 14.0 4.8 0.14 12.3 0.2 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF962) YWFCY PF14293.6 KFM74211.1 - 0.72 10.2 5.8 13 6.2 1.1 2.8 2 0 0 2 2 2 0 YWFCY protein SNF PF00209.18 KFM74212.1 - 1.9e-11 43.4 0.8 2.2e-11 43.2 0.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family HTH_Tnp_Tc3_2 PF01498.18 KFM74213.1 - 4.4e-16 58.9 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74213.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74213.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74213.1 - 0.0026 17.5 0.6 0.0074 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Cadherin_3 PF16184.5 KFM74215.1 - 0.28 11.2 15.2 3.6 7.6 0.9 5.0 6 0 0 6 6 6 0 Cadherin-like DHHC PF01529.20 KFM74217.1 - 2.7e-29 102.0 12.6 2.7e-29 102.0 12.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Prenyltransf PF01255.19 KFM74218.1 - 1.3e-05 24.8 0.0 5e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Arrestin_N PF00339.29 KFM74219.1 - 1.5e-31 109.4 0.3 1.4e-27 96.6 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFM74219.1 - 6e-23 81.8 0.1 1e-21 77.8 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF2393 PF09624.10 KFM74219.1 - 0.1 12.6 0.4 0.21 11.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) zf-C2H2 PF00096.26 KFM74220.1 - 3.1e-16 58.8 47.9 3.1e-05 24.2 0.4 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74220.1 - 4.8e-14 51.8 42.3 0.0047 17.6 0.2 7.4 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM74220.1 - 5.1e-13 48.8 50.1 3e-05 24.2 0.7 8.8 8 1 0 8 8 8 4 Zinc-finger double domain zf-met PF12874.7 KFM74220.1 - 2.6e-06 27.6 32.8 0.13 12.7 0.1 7.4 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM74220.1 - 1.2e-05 25.5 41.9 0.098 13.0 0.0 8.3 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFM74220.1 - 0.0076 15.8 26.7 0.034 13.7 0.2 6.0 7 0 0 7 7 7 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFM74220.1 - 0.011 16.4 3.7 0.011 16.4 3.7 3.6 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 KFM74220.1 - 0.064 13.3 35.2 0.14 12.1 1.2 6.7 6 0 0 6 6 6 0 C2H2-type zinc finger Ig_2 PF13895.6 KFM74220.1 - 0.1 13.0 1.1 0.83 10.0 0.1 2.6 3 0 0 3 3 3 0 Immunoglobulin domain ADK_lid PF05191.14 KFM74220.1 - 0.12 12.4 0.1 0.12 12.4 0.1 4.4 3 1 2 5 5 5 0 Adenylate kinase, active site lid Evr1_Alr PF04777.13 KFM74220.1 - 0.38 11.2 13.8 0.59 10.6 0.0 3.7 2 1 1 3 3 3 0 Erv1 / Alr family Zn-ribbon_8 PF09723.10 KFM74220.1 - 0.54 10.4 26.2 0.16 12.1 1.4 5.2 3 3 1 4 4 4 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFM74220.1 - 1.3 9.0 0.1 0.94 9.5 0.3 6.4 8 0 0 8 8 7 0 zinc-finger of a C2HC-type zf-CHY PF05495.12 KFM74220.1 - 1.4 9.5 31.8 1.1 9.7 6.0 3.8 2 2 1 3 3 3 0 CHY zinc finger zinc_ribbon_15 PF17032.5 KFM74220.1 - 1.5 9.6 25.8 1.9 9.3 0.4 3.9 1 1 2 4 4 4 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 KFM74220.1 - 2.1 8.4 30.9 0.18 11.8 6.3 4.1 2 2 1 3 3 3 0 zinc-ribbons LRR_8 PF13855.6 KFM74221.1 - 4.7e-24 83.9 13.0 1.3e-09 37.6 0.9 4.1 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFM74221.1 - 3e-13 49.7 8.4 6.8e-06 26.3 0.6 4.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM74221.1 - 1.8e-12 45.9 3.3 0.0082 16.5 0.1 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_5 PF13306.6 KFM74221.1 - 3.3e-08 33.5 0.1 5.8e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFM74221.1 - 1.5e-07 30.9 4.5 0.45 10.7 0.1 5.2 5 0 0 5 5 5 3 Leucine Rich repeat S-AdoMet_synt_C PF02773.16 KFM74223.1 - 4e-68 227.7 0.1 8.1e-68 226.7 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 KFM74223.1 - 2.4e-45 153.3 0.4 1.4e-44 150.8 0.2 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 KFM74223.1 - 4.3e-44 149.6 0.0 9.7e-44 148.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 KFM74223.1 - 0.014 14.2 0.3 0.4 9.4 0.1 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) DDE_3 PF13358.6 KFM74225.1 - 1.7e-16 60.3 0.1 2.3e-15 56.6 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74225.1 - 8.4e-16 58.0 6.5 1.5e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM74225.1 - 0.00076 20.0 1.5 0.00076 20.0 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM74225.1 - 0.0028 17.4 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM74225.1 - 0.016 15.3 0.1 0.068 13.3 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM74225.1 - 0.037 14.1 0.4 0.037 14.1 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM74225.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Biopterin_H PF00351.21 KFM74226.1 - 2.3e-19 69.7 0.1 3.4e-19 69.1 0.1 1.3 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT_4 PF13291.6 KFM74226.1 - 0.00081 19.9 0.1 0.0016 19.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain Bestrophin PF01062.21 KFM74227.1 - 3e-115 384.7 3.6 3.7e-115 384.4 3.6 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel SHMT PF00464.19 KFM74228.1 - 1.1e-10 40.7 0.0 1.3e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase SHMT PF00464.19 KFM74229.1 - 0.00016 20.4 0.0 0.00018 20.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase zf-FLZ PF04570.14 KFM74229.1 - 0.025 14.1 0.8 0.029 13.8 0.8 1.2 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 zf-H2C2_2 PF13465.6 KFM74230.1 - 1.5e-67 221.2 96.4 8.6e-08 32.3 2.5 12.6 13 0 0 13 13 13 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74230.1 - 2.9e-49 162.8 103.7 1.2e-05 25.4 0.1 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74230.1 - 5.3e-36 120.2 95.8 0.0008 20.0 0.6 12.1 12 0 0 12 12 12 11 C2H2-type zinc finger zf-met PF12874.7 KFM74230.1 - 5.2e-26 90.2 83.5 0.0003 21.1 0.6 12.2 12 0 0 12 12 12 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM74230.1 - 1.6e-22 79.3 63.1 0.0016 18.7 0.1 11.9 12 0 0 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM74230.1 - 5.3e-11 42.2 88.0 0.0016 18.4 0.8 12.1 12 0 0 12 12 12 6 C2H2-type zinc finger GAGA PF09237.11 KFM74230.1 - 4.3e-07 29.6 16.8 1.7 8.5 0.4 7.8 2 2 6 8 8 8 3 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM74230.1 - 2.1e-06 27.7 38.4 0.12 12.5 0.7 9.4 8 3 2 10 10 10 3 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.6 KFM74230.1 - 0.00025 20.7 60.6 0.017 14.9 0.8 11.5 12 0 0 12 12 11 4 C2H2-type zinc-finger domain BolA PF01722.18 KFM74230.1 - 0.0019 18.4 18.3 5.4 7.4 0.5 7.1 1 1 6 7 7 7 1 BolA-like protein zf-C2H2_2 PF12756.7 KFM74230.1 - 0.0019 18.5 72.1 2.2 8.7 0.4 10.6 1 1 9 10 10 10 4 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM74230.1 - 0.0039 17.3 44.7 0.013 15.6 6.1 5.1 1 1 4 5 5 5 1 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_9 PF16293.5 KFM74230.1 - 0.0061 16.4 45.0 0.18 11.7 0.0 10.3 5 4 6 11 11 11 1 C2H2 type zinc-finger (1 copy) DUF952 PF06108.12 KFM74230.1 - 0.014 15.4 0.0 5.7 7.0 0.0 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF952) DUF4764 PF15961.5 KFM74230.1 - 0.024 13.3 0.2 0.024 13.3 0.2 4.0 1 1 3 5 5 5 0 Domain of unknown function (DUF4764) PH_3 PF14593.6 KFM74230.1 - 0.069 13.3 1.9 16 5.7 0.4 3.9 3 1 0 3 3 3 0 PH domain zf-C2H2_11 PF16622.5 KFM74230.1 - 0.14 11.9 46.9 1.5 8.6 0.1 8.7 9 0 0 9 9 8 0 zinc-finger C2H2-type FYVE PF01363.21 KFM74230.1 - 7.1 6.8 56.8 52 4.1 2.2 7.2 3 2 2 5 5 5 0 FYVE zinc finger zf-DBF PF07535.12 KFM74230.1 - 8.5 6.6 50.7 6.6 6.9 0.7 10.5 11 0 0 11 11 11 0 DBF zinc finger THAP PF05485.12 KFM74232.1 - 0.005 17.7 0.1 0.008 17.1 0.1 1.3 1 0 0 1 1 1 1 THAP domain DUF630 PF04783.12 KFM74232.1 - 0.097 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF630) HTH_Tnp_Tc3_2 PF01498.18 KFM74234.1 - 2.3e-16 59.8 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74234.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease gag-asp_proteas PF13975.6 KFM74235.1 - 7.3e-11 42.5 0.0 2.5e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM74235.1 - 6.4e-09 36.3 0.0 1.9e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Apolipoprotein PF01442.18 KFM74235.1 - 9.8e-05 22.3 12.4 9.8e-05 22.3 12.4 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM74235.1 - 0.00031 20.8 0.5 3.2 7.8 0.2 3.1 2 1 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Asp_protease PF09668.10 KFM74235.1 - 0.00051 19.8 0.5 0.024 14.4 0.0 2.6 2 1 0 2 2 2 1 Aspartyl protease NPV_P10 PF05531.12 KFM74235.1 - 0.0078 16.6 11.1 3.6 8.1 1.0 4.2 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein RVP PF00077.20 KFM74235.1 - 0.014 15.7 0.0 0.3 11.4 0.0 2.7 2 0 0 2 2 2 0 Retroviral aspartyl protease HSBP1 PF06825.12 KFM74235.1 - 0.015 15.2 0.3 5.1 7.0 0.0 2.9 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF1640 PF07798.11 KFM74235.1 - 0.036 14.1 12.4 0.13 12.3 8.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF2884 PF11101.8 KFM74235.1 - 0.067 12.7 10.2 0.14 11.7 10.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) TPR_MLP1_2 PF07926.12 KFM74235.1 - 0.07 13.2 10.5 0.21 11.6 9.8 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1359 PF07097.11 KFM74235.1 - 0.092 13.0 3.2 0.14 12.4 1.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1359) FAD_SOX PF18371.1 KFM74235.1 - 0.24 11.8 2.3 4 7.8 0.0 3.1 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase ApoO PF09769.9 KFM74235.1 - 0.25 11.3 1.2 3.8 7.5 0.5 2.5 1 1 1 2 2 2 0 Apolipoprotein O DUF4709 PF15821.5 KFM74235.1 - 0.34 11.2 6.6 66 3.8 6.1 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4709) tRNA-synt_2c PF01411.19 KFM74235.1 - 0.35 9.3 5.5 0.55 8.7 5.5 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (A) CLZ PF16526.5 KFM74235.1 - 0.44 10.9 7.2 0.69 10.3 0.3 3.5 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MIS13 PF08202.11 KFM74235.1 - 0.8 8.9 7.5 0.61 9.3 5.4 1.8 2 0 0 2 2 2 0 Mis12-Mtw1 protein family DUF1664 PF07889.12 KFM74235.1 - 0.83 9.7 16.5 0.14 12.2 8.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KFM74235.1 - 0.92 8.8 5.7 4.5 6.5 5.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mer2 PF09074.10 KFM74235.1 - 1.1 9.0 9.5 4.1 7.2 9.5 2.0 1 1 0 1 1 1 0 Mer2 Exonuc_VII_L PF02601.15 KFM74235.1 - 1.1 8.7 8.3 2.1 7.8 8.3 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4164 PF13747.6 KFM74235.1 - 1.4 9.3 11.0 1.1 9.6 2.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Phasin PF05597.11 KFM74235.1 - 1.9 8.5 16.8 1.1e+02 2.8 0.0 3.5 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoLp-III PF07464.11 KFM74235.1 - 2.6 8.1 14.8 6.1 6.9 14.8 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PKK PF12474.8 KFM74235.1 - 2.9 8.0 13.8 0.29 11.3 8.3 2.0 1 1 0 1 1 1 0 Polo kinase kinase FAM25 PF15825.5 KFM74235.1 - 3.8 7.9 9.8 21 5.6 5.1 2.8 1 1 1 2 2 2 0 FAM25 family CdvA PF18822.1 KFM74235.1 - 3.9 7.3 12.0 7.9 6.3 6.1 3.1 2 1 1 3 3 2 0 CdvA-like coiled-coil domain HalX PF08663.10 KFM74235.1 - 4.6 7.6 5.4 42 4.6 1.2 3.5 3 1 1 4 4 3 0 HalX domain JIP_LZII PF16471.5 KFM74235.1 - 5.1 7.4 10.2 42 4.4 0.0 4.1 2 1 2 4 4 4 0 JNK-interacting protein leucine zipper II UXS1_N PF11803.8 KFM74235.1 - 6.2 7.3 5.4 2 8.9 0.4 2.6 2 1 1 3 3 2 0 UDP-glucuronate decarboxylase N-terminal Focal_AT PF03623.13 KFM74235.1 - 6.2 6.8 10.5 0.6 10.1 4.2 2.4 2 1 1 3 3 2 0 Focal adhesion targeting region Spectrin PF00435.21 KFM74235.1 - 6.9 7.2 8.9 1.5 9.3 4.4 2.2 2 1 0 2 2 2 0 Spectrin repeat TipAS PF07739.13 KFM74235.1 - 8.5 7.0 7.9 21 5.7 6.6 2.3 2 1 1 3 3 2 0 TipAS antibiotic-recognition domain Integrase_H2C2 PF17921.1 KFM74236.1 - 7.5e-11 42.0 0.4 9.3e-11 41.7 0.4 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM74236.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 H2C2 zinc finger ABC_trans_CmpB PF06541.11 KFM74237.1 - 2.9e-10 40.6 12.3 3.9e-10 40.2 12.3 1.2 1 0 0 1 1 1 1 Putative ABC-transporter type IV Kelch_3 PF13415.6 KFM74238.1 - 2.8e-30 104.0 16.2 1.8e-07 31.3 0.0 7.7 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM74238.1 - 2.6e-29 100.7 6.1 6.7e-05 22.8 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFM74238.1 - 7.7e-29 99.0 8.1 2.4e-09 37.1 0.0 5.9 5 1 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 KFM74238.1 - 1.1e-27 95.4 12.0 6.4e-08 32.1 0.0 6.5 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFM74238.1 - 1.6e-27 95.3 14.8 2.8e-09 36.8 0.1 6.7 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFM74238.1 - 2.1e-27 94.0 13.2 9.9e-06 25.3 0.0 6.5 6 1 0 6 6 6 5 Kelch motif HTH_Tnp_Tc3_2 PF01498.18 KFM74239.1 - 1.3e-11 44.6 0.7 2.3e-11 43.8 0.7 1.4 1 0 0 1 1 1 1 Transposase PAX PF00292.18 KFM74239.1 - 0.0022 17.9 0.0 0.0058 16.6 0.0 1.6 1 1 1 2 2 2 1 'Paired box' domain HTH_32 PF13565.6 KFM74239.1 - 0.068 13.8 7.7 0.93 10.1 1.6 2.4 1 1 1 2 2 2 0 Homeodomain-like domain HTH_3 PF01381.22 KFM74239.1 - 0.08 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix DDE_3 PF13358.6 KFM74240.1 - 6.7e-16 58.4 0.1 6.9e-15 55.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74240.1 - 8.9e-16 57.9 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM74240.1 - 0.0008 20.0 1.5 0.0008 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM74240.1 - 0.0031 17.2 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM74240.1 - 0.018 15.2 0.1 0.071 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM74240.1 - 0.039 14.0 0.4 0.039 14.0 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix ATG11 PF10377.9 KFM74241.1 - 0.022 14.8 0.1 0.03 14.4 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 MLVIN_C PF18697.1 KFM74241.1 - 0.046 13.8 0.2 0.17 12.0 0.0 2.0 2 1 1 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF4537 PF15057.6 KFM74241.1 - 0.05 13.6 0.1 0.091 12.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Acylphosphatase PF00708.18 KFM74242.1 - 8.6e-10 38.9 0.0 9.2e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase IBR PF01485.21 KFM74243.1 - 4.2e-14 52.5 24.8 1.2e-08 35.0 3.9 5.4 5 0 0 5 5 5 2 IBR domain, a half RING-finger domain HA2 PF04408.23 KFM74243.1 - 6.7e-10 39.2 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) SLS PF14611.6 KFM74243.1 - 0.004 17.0 2.2 0.025 14.4 0.2 2.7 3 0 0 3 3 3 1 Mitochondrial inner-membrane-bound regulator NitrOD2 PF18550.1 KFM74243.1 - 0.062 13.4 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Nitrososphaera output domain 2 KH_1 PF00013.29 KFM74243.1 - 0.082 12.7 0.1 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 KH domain Get5_bdg PF16843.5 KFM74244.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein IBR PF01485.21 KFM74245.1 - 3.8e-13 49.5 24.8 1.2e-08 35.1 5.5 4.6 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain RRM_1 PF00076.22 KFM74245.1 - 0.0003 20.6 0.2 4.6 7.1 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SLS PF14611.6 KFM74245.1 - 0.00036 20.4 6.3 0.0035 17.2 0.3 3.5 3 1 0 3 3 3 1 Mitochondrial inner-membrane-bound regulator KH_1 PF00013.29 KFM74245.1 - 0.027 14.3 0.7 3.5 7.5 0.1 3.7 3 0 0 3 3 3 0 KH domain KH_2 PF07650.17 KFM74245.1 - 0.028 14.2 3.5 0.029 14.2 0.7 2.5 2 0 0 2 2 2 0 KH domain CAF1 PF04857.20 KFM74245.1 - 0.053 12.7 0.1 0.087 12.0 0.1 1.4 1 0 0 1 1 1 0 CAF1 family ribonuclease HA2 PF04408.23 KFM74246.1 - 1.3e-10 41.5 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Retrotrans_gag PF03732.17 KFM74247.1 - 0.38 11.1 2.2 0.84 10.0 0.1 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein EF-G-binding_N PF07299.11 KFM74247.1 - 0.5 10.9 3.9 1.1 9.8 0.3 2.6 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF2072 PF09845.9 KFM74247.1 - 2.5 8.4 6.7 0.37 11.0 2.0 1.9 2 0 0 2 2 2 0 Zn-ribbon containing protein DUF4274 PF14096.6 KFM74248.1 - 0.049 13.6 0.1 2.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4274) E3_UbLigase_RBR PF18091.1 KFM74250.1 - 3e-20 72.1 0.5 3e-20 72.1 0.5 3.6 3 0 0 3 3 3 1 E3 Ubiquitin Ligase RBR C-terminal domain IBR PF01485.21 KFM74250.1 - 2.1e-06 27.9 6.2 2.1e-06 27.9 6.2 4.8 5 0 0 5 5 5 2 IBR domain, a half RING-finger domain DDE_1 PF03184.19 KFM74251.1 - 3.9e-50 169.9 0.1 7e-50 169.1 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM74251.1 - 1.8e-12 47.1 0.0 1.5e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM74251.1 - 0.00087 18.9 0.0 0.003 17.2 0.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM74252.1 - 2.2e-16 59.8 2.2 4.1e-16 59.0 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74252.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Thioredoxin PF00085.20 KFM74253.1 - 5.2e-30 103.5 0.3 6.1e-30 103.3 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KFM74253.1 - 1.4e-08 34.7 0.2 1.5e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFM74253.1 - 2.6e-08 34.1 0.5 5.7e-05 23.4 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KFM74253.1 - 4.2e-07 30.4 0.1 1.2e-05 25.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KFM74253.1 - 4.5e-07 29.7 0.0 5.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFM74253.1 - 1.2e-05 24.8 0.1 1.4e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KFM74253.1 - 5.4e-05 22.9 0.0 6.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 KFM74253.1 - 5.7e-05 23.2 0.3 9.8e-05 22.5 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.16 KFM74253.1 - 0.0016 18.3 0.3 0.0016 18.2 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_3 PF13192.6 KFM74253.1 - 0.0039 17.2 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.11 KFM74253.1 - 0.026 14.5 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE T4_deiodinase PF00837.17 KFM74253.1 - 0.035 13.4 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase TraF PF13728.6 KFM74253.1 - 0.054 13.3 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Tim44 PF04280.15 KFM74254.1 - 5.4e-05 23.3 0.1 0.00012 22.2 0.1 1.5 1 0 0 1 1 1 1 Tim44-like domain PX PF00787.24 KFM74255.1 - 1e-19 70.6 0.8 3.4e-19 68.9 0.1 2.2 3 0 0 3 3 3 1 PX domain PDZ PF00595.24 KFM74255.1 - 1.1e-16 60.9 0.5 2.3e-16 59.9 0.5 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM74255.1 - 7.1e-16 57.8 0.6 1.8e-15 56.5 0.2 1.9 2 0 0 2 2 2 1 PDZ domain RA PF00788.23 KFM74255.1 - 2.2e-12 47.5 0.1 4e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ_2 PF13180.6 KFM74255.1 - 1.2e-05 25.5 0.8 3.8e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 PDZ domain SNX17_FERM_C PF18116.1 KFM74255.1 - 0.00062 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain TLC PF03219.14 KFM74255.1 - 0.013 14.2 0.1 0.019 13.7 0.1 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter USP7_C2 PF14533.6 KFM74255.1 - 0.017 14.8 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal RBD PF02196.15 KFM74255.1 - 0.023 14.8 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Raf-like Ras-binding domain Ras_bdg_2 PF14847.6 KFM74255.1 - 0.024 15.0 0.1 0.084 13.2 0.0 1.9 2 0 0 2 2 2 0 Ras-binding domain of Byr2 FERM_N PF09379.10 KFM74255.1 - 0.088 12.8 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 FERM N-terminal domain Tricorn_PDZ PF14685.6 KFM74255.1 - 0.2 11.6 1.0 1.2 9.1 0.3 2.5 2 1 1 3 3 2 0 Tricorn protease PDZ domain CDC37_M PF08565.11 KFM74256.1 - 5.6e-26 90.8 11.9 1.3e-25 89.6 3.3 2.3 2 0 0 2 2 2 2 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 KFM74256.1 - 1.4e-13 51.9 17.1 1.4e-13 51.9 17.1 2.9 2 2 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 KFM74256.1 - 2.1e-13 50.2 0.0 2.1e-13 50.2 0.0 3.5 3 1 1 4 4 4 1 Cdc37 C terminal domain GIT_CC PF16559.5 KFM74256.1 - 0.47 10.4 7.3 17 5.4 6.0 2.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2730 PF10805.8 KFM74256.1 - 0.49 10.5 5.4 1.5 8.9 5.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 KFM74256.1 - 6.3 6.1 6.6 1.7 7.9 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MBD_C PF14048.6 KFM74257.1 - 6.6e-33 113.3 0.2 9.9e-33 112.7 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa PF16564.5 KFM74257.1 - 2.4e-29 101.3 0.3 2.4e-29 101.3 0.3 1.6 2 0 0 2 2 2 1 p55-binding region of Methyl-CpG-binding domain proteins MBD MBD PF01429.19 KFM74257.1 - 7.7e-28 96.0 0.3 1.5e-20 72.7 0.1 2.3 1 1 1 2 2 2 2 Methyl-CpG binding domain RVT_1 PF00078.27 KFM74258.1 - 8.1e-14 51.7 0.0 8.6e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTR2 PF00854.21 KFM74259.1 - 3.8e-110 368.4 19.2 3.3e-100 335.7 3.6 2.4 3 0 0 3 3 3 2 POT family TMEM223 PF14640.6 KFM74260.1 - 5.4e-39 134.0 0.2 8.1e-39 133.4 0.2 1.3 1 0 0 1 1 1 1 Transmembrane protein 223 MADF_DNA_bdg PF10545.9 KFM74261.1 - 6.9e-06 26.3 7.5 1.3e-05 25.4 6.9 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like FliS PF02561.14 KFM74261.1 - 0.022 15.0 1.3 0.027 14.7 1.3 1.3 1 0 0 1 1 1 0 Flagellar protein FliS DUF5311 PF17238.2 KFM74261.1 - 0.13 12.1 2.2 0.21 11.4 1.9 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5311) Myb_DNA-bind_4 PF13837.6 KFM74261.1 - 0.14 12.6 9.0 3.1 8.3 9.0 2.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain 7TM_GPCR_Srab PF10292.9 KFM74262.1 - 0.11 11.4 0.3 0.11 11.4 0.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor DDE_3 PF13358.6 KFM74264.1 - 1.6e-12 47.4 0.0 2.5e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74264.1 - 1.8e-05 24.9 0.2 3.9e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Transposase Alpha_kinase PF02816.18 KFM74265.1 - 1.4e-58 198.1 0.1 3.1e-58 196.9 0.1 1.6 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 KFM74265.1 - 1e-07 32.4 9.8 0.14 12.9 0.1 4.4 4 0 0 4 4 4 3 Sel1 repeat COX6B PF02297.17 KFM74266.1 - 5.1e-18 65.1 6.2 6.1e-18 64.8 6.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb tRNA_int_endo_N PF02778.14 KFM74267.1 - 0.085 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain tRNA_int_endo_N PF02778.14 KFM74268.1 - 0.002 17.7 0.0 0.0051 16.5 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain tRNA_int_end_N2 PF12928.7 KFM74268.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term DUF2371 PF10177.9 KFM74268.1 - 0.15 12.3 0.0 0.69 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF4371 PF14291.6 KFM74271.1 - 9.8e-08 31.9 0.0 1.1e-07 31.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) PIF1 PF05970.14 KFM74272.1 - 4.2e-41 141.3 0.0 5.1e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFM74272.1 - 4.9e-10 39.5 0.0 6.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM74272.1 - 0.0093 16.4 0.0 0.016 15.6 0.0 1.6 1 1 1 2 2 2 1 AAA ATPase domain DDE_1 PF03184.19 KFM74273.1 - 2.5e-33 115.2 0.1 3.8e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease P21-Arc PF04062.14 KFM74274.1 - 2.5e-66 223.0 0.0 2.7e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Tugs PF17840.1 KFM74274.1 - 0.048 13.8 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain dNK PF01712.19 KFM74274.1 - 0.055 13.3 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase Hormone_3 PF00159.18 KFM74274.1 - 0.15 12.1 0.1 0.37 10.9 0.1 1.6 1 0 0 1 1 1 0 Pancreatic hormone peptide Zona_pellucida PF00100.23 KFM74276.1 - 5e-10 39.6 0.0 6.7e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain zf-H2C2_2 PF13465.6 KFM74277.1 - 1.9e-84 274.6 81.4 9.6e-09 35.3 0.3 12.4 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74277.1 - 1.9e-52 172.9 96.9 5.4e-06 26.6 0.5 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74277.1 - 1.2e-37 125.2 93.0 0.0011 19.7 2.1 11.5 12 0 0 12 12 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM74277.1 - 2e-30 104.3 85.5 0.00047 20.5 1.3 11.4 11 0 0 11 11 11 10 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74277.1 - 2e-18 65.9 83.4 0.0049 16.8 1.1 12.7 12 1 0 12 12 12 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74277.1 - 1.5e-15 57.0 64.8 0.086 13.1 0.6 11.7 11 0 0 11 11 11 9 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM74277.1 - 2.9e-12 46.1 53.7 0.26 11.1 1.2 10.9 11 0 0 11 11 11 7 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM74277.1 - 1.5e-06 27.9 48.3 3.5 7.6 0.1 12.1 12 0 0 12 12 12 2 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM74277.1 - 6.4e-06 26.0 37.2 0.13 12.3 1.4 6.6 4 1 2 6 6 6 5 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 KFM74277.1 - 2.5e-05 23.9 4.5 0.0049 16.6 0.4 10.1 10 0 0 10 10 10 3 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM74277.1 - 0.00015 21.7 42.5 0.88 9.7 0.2 10.4 7 3 4 11 11 11 2 Sec23/Sec24 zinc finger Tox-HNH-HHH PF15637.6 KFM74277.1 - 0.00021 21.4 3.2 15 5.8 0.1 4.8 1 1 3 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif YyzF PF14116.6 KFM74277.1 - 0.00029 20.8 31.1 13 5.9 0.0 10.5 11 0 0 11 11 11 0 YyzF-like protein BHD_1 PF10403.9 KFM74277.1 - 0.00059 19.6 2.1 0.21 11.5 0.0 4.4 4 2 1 5 5 5 1 Rad4 beta-hairpin domain 1 DUF2790 PF10976.8 KFM74277.1 - 0.0027 17.7 0.3 0.42 10.6 0.0 3.9 4 1 0 4 4 3 1 Protein of unknown function (DUF2790) FYVE PF01363.21 KFM74277.1 - 0.0028 17.8 57.3 2.3 8.4 8.7 6.7 1 1 5 6 6 6 4 FYVE zinc finger zf-CHCC PF10276.9 KFM74277.1 - 0.0037 17.3 10.3 1.4e+02 2.6 0.0 8.3 10 0 0 10 10 9 0 Zinc-finger domain BolA PF01722.18 KFM74277.1 - 0.0039 17.4 13.5 0.73 10.2 0.4 5.6 1 1 3 5 5 5 1 BolA-like protein C1_1 PF00130.22 KFM74277.1 - 0.014 15.3 60.0 1.3 9.0 2.4 10.4 1 1 9 11 11 11 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KFM74277.1 - 0.024 14.8 31.5 1.7 8.8 1.2 7.0 3 3 4 7 7 7 0 Zinc ribbon domain DUF2256 PF10013.9 KFM74277.1 - 0.041 14.0 40.2 22 5.3 0.1 11.0 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFM74277.1 - 0.11 13.3 43.6 14 6.5 7.0 6.2 1 1 6 7 7 7 0 zinc-ribbon family DZR PF12773.7 KFM74277.1 - 0.2 11.7 37.7 18 5.4 4.1 6.2 1 1 2 3 3 2 0 Double zinc ribbon zf_UBZ PF18439.1 KFM74277.1 - 0.39 10.3 51.6 1.2 8.8 0.2 10.9 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger TerY_C PF15616.6 KFM74277.1 - 1.8 8.7 26.8 0.23 11.5 2.6 5.5 1 1 6 7 7 7 0 TerY-C metal binding domain zf-RRPl_C4 PF17026.5 KFM74277.1 - 6.9 6.8 45.3 4.1 7.6 6.5 5.5 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type Synaptobrevin PF00957.21 KFM74279.1 - 1.6e-14 53.5 0.2 2.2e-14 53.0 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFM74279.1 - 2.2e-07 30.8 0.0 6.8e-07 29.2 0.0 1.8 1 1 1 2 2 2 1 Regulated-SNARE-like domain Ctf8 PF09696.10 KFM74281.1 - 0.043 14.1 0.3 0.15 12.4 0.3 2.0 1 1 0 1 1 1 0 Ctf8 VGCC_alpha2 PF08473.11 KFM74283.1 - 0.13 11.0 0.0 0.28 9.9 0.0 1.3 1 1 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd VGCC_alpha2 PF08473.11 KFM74284.1 - 1.8e-07 30.3 0.0 8.6e-07 28.1 0.0 1.8 1 1 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd Usher_TcfC PF17271.2 KFM74284.1 - 0.034 12.9 0.1 0.043 12.6 0.1 1.1 1 0 0 1 1 1 0 TcfC Usher-like barrel domain Pkinase PF00069.25 KFM74286.1 - 3.3e-12 46.4 0.0 4e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM74286.1 - 3.5e-07 29.8 0.0 4.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PGM_PMM_II PF02879.16 KFM74287.1 - 8e-17 61.7 0.1 2.1e-16 60.4 0.1 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KFM74287.1 - 4.1e-15 56.0 0.0 6.1e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KFM74287.1 - 1.8e-05 24.8 0.0 3.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.16 KFM74288.1 - 4e-30 104.3 0.0 5.4e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Dzip-like_N PF13815.6 KFM74288.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal YL1 PF05764.13 KFM74289.1 - 7.6e-16 59.0 14.3 1.1e-15 58.5 14.3 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 KFM74289.1 - 1.6e-12 46.9 0.2 5.9e-12 45.1 0.2 2.0 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Pinin_SDK_memA PF04696.13 KFM74289.1 - 0.036 14.1 10.7 0.064 13.3 10.7 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region TerD PF02342.18 KFM74289.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 TerD domain PTPlike_phytase PF14566.6 KFM74289.1 - 0.11 12.6 6.5 0.13 12.3 5.6 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate EGF PF00008.27 KFM74290.1 - 1.8e-05 25.0 1.3 4.6e-05 23.6 1.3 1.8 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFM74290.1 - 0.0013 19.3 0.7 0.0042 17.7 0.7 2.0 1 0 0 1 1 1 1 Human growth factor-like EGF Laminin_EGF PF00053.24 KFM74290.1 - 0.42 10.8 3.2 0.93 9.7 3.2 1.6 1 1 0 1 1 1 0 Laminin EGF domain DDE_3 PF13358.6 KFM74292.1 - 9.1e-16 57.9 0.1 1e-14 54.5 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74292.1 - 1.3e-10 41.3 1.0 2.8e-10 40.3 1.0 1.6 1 0 0 1 1 1 1 Transposase G6PD_N PF00479.22 KFM74292.1 - 0.091 13.4 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Amidase PF01425.21 KFM74293.1 - 2.1e-10 40.2 0.0 2.6e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KFM74294.1 - 8.5e-65 219.5 0.0 1.2e-64 219.0 0.0 1.2 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KFM74295.1 - 2.2e-07 30.2 0.0 2.4e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Amidase TMEM169 PF15052.6 KFM74295.1 - 0.01 15.9 0.1 0.047 13.8 0.1 1.8 2 0 0 2 2 2 0 TMEM169 protein family Amidase PF01425.21 KFM74296.1 - 6.6e-72 242.9 0.0 9.4e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Amidase Arf PF00025.21 KFM74297.1 - 0.00018 21.0 0.0 0.00037 20.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF4164 PF13747.6 KFM74297.1 - 0.003 17.8 9.4 0.009 16.3 9.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) PIEZO PF15917.5 KFM74297.1 - 0.013 15.0 3.5 0.013 15.0 3.5 1.5 2 0 0 2 2 2 0 Piezo SRP-alpha_N PF04086.13 KFM74297.1 - 0.016 15.2 4.7 0.024 14.6 4.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Spore_III_AF PF09581.10 KFM74297.1 - 2.7 8.0 8.0 5 7.1 8.0 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) USP19_linker PF16602.5 KFM74297.1 - 4.9 7.7 7.4 0.33 11.5 0.3 2.5 1 1 1 2 2 2 0 Linker region of USP19 deubiquitinase HTH_Tnp_Tc3_2 PF01498.18 KFM74299.1 - 1.6e-08 34.7 0.0 3.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_IS630 PF01710.16 KFM74299.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE_3 PF13358.6 KFM74301.1 - 0.0002 21.1 0.0 0.00021 21.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM74302.1 - 7.7e-75 244.2 74.0 2e-09 37.4 1.2 12.0 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74302.1 - 5.2e-55 181.0 92.0 3.4e-06 27.2 1.5 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74302.1 - 9.9e-43 141.1 85.9 0.00045 20.8 1.2 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM74302.1 - 1.2e-27 95.4 81.1 0.00026 21.3 0.7 11.3 11 0 0 11 11 11 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM74302.1 - 8.8e-19 67.3 61.6 0.039 14.3 0.3 11.5 10 1 1 11 11 11 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM74302.1 - 7.9e-14 51.3 83.7 0.0016 18.4 0.2 12.1 12 1 0 12 12 12 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM74302.1 - 3.6e-12 45.8 59.9 0.029 14.1 1.0 11.3 11 0 0 11 11 11 6 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM74302.1 - 1.5e-08 34.5 46.8 0.82 9.8 0.3 11.1 7 4 5 12 12 12 5 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 KFM74302.1 - 3.6e-06 27.2 75.2 0.62 10.4 0.4 10.9 1 1 9 10 10 10 4 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFM74302.1 - 8e-06 25.6 24.9 0.75 9.6 0.2 8.0 2 2 5 8 8 8 4 GAGA factor zf-C2H2_9 PF16293.5 KFM74302.1 - 1.4e-05 24.8 47.7 0.092 12.6 0.7 10.6 2 2 9 11 11 11 4 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM74302.1 - 7.2e-05 23.0 20.1 0.72 10.2 0.7 7.1 1 1 7 8 8 8 3 BolA-like protein zf-MYST PF17772.1 KFM74302.1 - 0.00027 20.5 49.1 0.25 11.0 0.4 9.7 4 3 6 10 10 10 2 MYST family zinc finger domain DUF2256 PF10013.9 KFM74302.1 - 0.00073 19.6 41.4 9.6 6.4 0.1 10.7 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) Tox-HNH-HHH PF15637.6 KFM74302.1 - 0.001 19.2 4.1 0.88 9.8 0.1 4.3 2 2 3 5 5 5 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2HC_2 PF13913.6 KFM74302.1 - 0.0017 18.2 44.7 0.5 10.3 0.1 10.5 11 1 0 11 11 11 3 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM74302.1 - 0.02 15.0 46.3 2 8.5 8.1 5.1 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type ADK_lid PF05191.14 KFM74302.1 - 0.021 14.8 36.9 3 7.9 0.8 7.5 5 3 0 5 5 5 0 Adenylate kinase, active site lid TRAF6_Z2 PF18048.1 KFM74302.1 - 0.039 14.1 55.6 0.39 10.9 0.6 10.5 11 0 0 11 11 11 0 TNF receptor-associated factor 6 zinc finger 2 zf-DBF PF07535.12 KFM74302.1 - 0.16 12.1 49.1 9.5 6.4 0.4 10.0 11 0 0 11 11 9 0 DBF zinc finger Baculo_IE-1 PF05290.11 KFM74302.1 - 0.38 10.7 37.0 1.1 9.2 6.2 7.2 1 1 3 4 4 4 0 Baculovirus immediate-early protein (IE-0) Ribosomal_L35p PF01632.19 KFM74302.1 - 0.56 10.7 13.1 47 4.6 0.0 5.6 3 2 2 6 6 6 0 Ribosomal protein L35 Zf_RING PF16744.5 KFM74302.1 - 1.2 9.3 52.6 4.4 7.5 0.4 10.1 1 1 7 9 9 9 0 KIAA1045 RING finger zinc_ribbon_15 PF17032.5 KFM74302.1 - 1.4 9.7 46.1 1.8 9.3 3.0 5.8 1 1 6 8 8 8 0 zinc-ribbon family C1_1 PF00130.22 KFM74302.1 - 2.1 8.3 60.1 13 5.8 0.5 10.0 2 2 8 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.6 KFM74303.1 - 1.7e-57 189.4 75.9 6.8e-08 32.6 1.5 11.1 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74303.1 - 5.9e-51 168.2 80.9 4.5e-06 26.8 1.2 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74303.1 - 1e-33 113.0 77.3 0.001 19.7 1.0 10.2 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM74303.1 - 3.3e-23 81.3 71.4 0.00085 19.6 0.6 10.6 9 1 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74303.1 - 2e-16 59.5 70.1 0.00037 20.4 0.5 11.2 11 0 0 11 11 11 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74303.1 - 3.3e-11 43.2 58.7 0.036 14.4 0.4 10.8 10 1 1 11 11 11 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM74303.1 - 1.9e-07 30.7 61.0 0.11 12.2 0.2 10.6 10 0 0 10 10 10 4 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM74303.1 - 6.2e-07 29.4 35.4 0.63 10.1 1.3 9.5 6 2 4 10 10 10 5 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM74303.1 - 1.1e-06 28.4 23.9 0.062 13.1 0.3 7.1 2 1 5 8 8 8 2 GAGA factor zf-C2H2_9 PF16293.5 KFM74303.1 - 4.8e-06 26.3 46.2 0.15 11.9 0.4 9.9 2 1 8 10 10 10 4 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM74303.1 - 2.7e-05 24.2 41.2 6 7.1 0.1 10.0 10 0 0 10 10 10 1 DBF zinc finger BolA PF01722.18 KFM74303.1 - 0.00014 22.0 25.0 0.44 10.9 1.0 7.5 1 1 7 8 8 8 2 BolA-like protein zf-C2H2_2 PF12756.7 KFM74303.1 - 0.0007 19.9 72.2 0.69 10.3 2.8 9.5 1 1 7 8 8 8 4 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM74303.1 - 0.0012 18.9 41.0 0.17 12.0 6.7 4.5 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type ADK_lid PF05191.14 KFM74303.1 - 0.0033 17.4 26.8 0.21 11.6 1.8 6.2 2 1 5 7 7 7 3 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM74303.1 - 0.0056 17.4 38.7 2 9.2 2.5 5.2 2 1 2 5 5 5 4 zinc-ribbon family zf-CHCC PF10276.9 KFM74303.1 - 0.0095 16.0 13.8 69 3.6 0.0 7.9 10 0 0 10 10 10 0 Zinc-finger domain zf-MYST PF17772.1 KFM74303.1 - 0.041 13.5 48.0 0.25 11.0 0.6 9.7 3 2 7 10 10 10 0 MYST family zinc finger domain YyzF PF14116.6 KFM74303.1 - 0.61 10.2 31.9 16 5.6 0.1 9.0 10 0 0 10 10 10 0 YyzF-like protein zf-C2HC_2 PF13913.6 KFM74303.1 - 2.6 8.0 44.8 3.7 7.6 0.2 10.0 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFM74304.1 - 2.8e-67 220.4 72.4 2.6e-08 33.9 1.8 10.1 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74304.1 - 1.2e-44 148.3 88.2 2.4e-05 24.5 1.3 9.2 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74304.1 - 1e-30 103.7 80.6 0.0014 19.3 1.3 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM74304.1 - 1.8e-24 85.3 78.3 0.0062 16.9 1.3 9.3 9 0 0 9 9 9 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM74304.1 - 1e-14 54.4 54.2 0.014 15.6 0.2 9.4 9 0 0 9 9 9 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM74304.1 - 2.2e-13 49.7 45.1 0.032 14.0 0.1 9.5 9 0 0 9 9 9 6 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM74304.1 - 1.1e-10 41.2 66.7 0.06 13.4 1.1 9.6 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM74304.1 - 2.5e-10 40.0 41.2 0.93 9.4 0.2 9.0 1 1 8 9 9 9 5 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM74304.1 - 7.9e-09 35.2 39.2 0.1 12.5 0.3 9.4 9 0 0 9 9 9 3 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM74304.1 - 5.8e-08 32.7 39.3 3.7 7.7 0.0 9.2 9 0 0 9 9 9 2 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM74304.1 - 6.6e-08 32.6 35.0 0.0037 17.3 6.4 4.2 1 1 4 5 5 5 5 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM74304.1 - 4.5e-07 29.9 30.5 9.1 6.5 0.1 9.1 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) TRAF6_Z2 PF18048.1 KFM74304.1 - 8.3e-07 29.0 44.0 0.0071 16.4 2.5 8.8 9 0 0 9 9 9 3 TNF receptor-associated factor 6 zinc finger 2 BolA PF01722.18 KFM74304.1 - 4e-06 27.0 18.6 0.16 12.3 1.2 5.8 1 1 4 6 6 6 3 BolA-like protein zf-C2H2_11 PF16622.5 KFM74304.1 - 4.5e-05 23.1 56.8 0.036 13.8 0.1 8.8 9 0 0 9 9 9 4 zinc-finger C2H2-type Tox-HNH-HHH PF15637.6 KFM74304.1 - 0.00012 22.1 9.3 4.7 7.4 0.3 4.8 1 1 4 5 5 5 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF3396 PF11876.8 KFM74304.1 - 0.00015 21.3 0.0 0.83 9.1 0.0 4.5 1 1 5 6 6 6 1 Protein of unknown function (DUF3396) C1_1 PF00130.22 KFM74304.1 - 0.00063 19.6 54.1 0.26 11.2 7.5 8.1 1 1 7 8 8 8 1 Phorbol esters/diacylglycerol binding domain (C1 domain) YyzF PF14116.6 KFM74304.1 - 0.001 19.0 25.6 33 4.6 0.1 8.9 9 0 0 9 9 9 0 YyzF-like protein GAGA PF09237.11 KFM74304.1 - 0.0021 17.8 23.0 0.081 12.7 0.1 6.9 2 1 7 9 9 9 1 GAGA factor zinc_ribbon_15 PF17032.5 KFM74304.1 - 0.0096 16.6 35.7 4.7 8.0 2.1 4.9 1 1 2 4 4 4 2 zinc-ribbon family DUF952 PF06108.12 KFM74304.1 - 0.015 15.3 3.0 30 4.7 0.1 4.7 1 1 4 6 6 6 0 Protein of unknown function (DUF952) ADK_lid PF05191.14 KFM74304.1 - 0.087 12.8 40.9 0.56 10.2 2.9 6.6 4 1 3 7 7 7 0 Adenylate kinase, active site lid FYVE PF01363.21 KFM74304.1 - 0.13 12.4 47.5 1.4 9.1 9.3 4.7 1 1 5 6 6 6 0 FYVE zinc finger zf-Dof PF02701.15 KFM74304.1 - 0.14 12.3 27.6 3.2 8.0 0.5 7.3 2 1 6 8 8 8 0 Dof domain, zinc finger NAD_kinase PF01513.21 KFM74304.1 - 0.18 11.0 2.2 17 4.5 0.9 3.8 1 1 0 2 2 2 0 ATP-NAD kinase VirE1 PF12189.8 KFM74304.1 - 0.29 11.3 4.4 6.1 7.0 0.1 3.6 4 2 2 6 6 4 0 Single-strand DNA-binding protein zf-Sec23_Sec24 PF04810.15 KFM74304.1 - 0.37 10.9 29.7 36 4.5 1.1 8.6 5 4 5 10 10 10 0 Sec23/Sec24 zinc finger zf-HIT PF04438.16 KFM74304.1 - 0.76 9.7 45.6 2.3 8.2 0.6 9.0 9 0 0 9 9 9 0 HIT zinc finger Viral_cys_rich PF08008.12 KFM74304.1 - 1.1 9.3 10.8 1.9 8.5 0.2 4.5 3 2 3 6 6 6 0 Viral cysteine rich Ribosomal_L35p PF01632.19 KFM74304.1 - 1.6 9.3 18.9 15 6.1 0.4 6.0 3 3 3 6 6 6 0 Ribosomal protein L35 PqqA PF08042.11 KFM74304.1 - 2.7 8.2 5.1 4.5e+02 1.1 0.0 5.2 8 0 0 8 8 5 0 PqqA family zf-FPG_IleRS PF06827.14 KFM74304.1 - 3.9 7.4 34.0 54 3.8 0.1 9.1 8 2 2 10 10 10 0 Zinc finger found in FPG and IleRS Caveolin PF01146.17 KFM74305.1 - 1.9e-47 160.5 0.8 2.5e-47 160.2 0.8 1.1 1 0 0 1 1 1 1 Caveolin LMBR1 PF04791.16 KFM74305.1 - 0.0067 15.4 0.0 0.0084 15.1 0.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein PPL5 PF18168.1 KFM74305.1 - 0.012 14.9 4.0 0.015 14.6 4.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Draxin PF15550.6 KFM74305.1 - 0.034 14.0 8.5 0.042 13.7 8.5 1.0 1 0 0 1 1 1 0 Draxin DUF913 PF06025.12 KFM74305.1 - 0.3 10.0 4.1 0.36 9.7 4.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3807 PF12720.7 KFM74305.1 - 0.47 10.7 14.4 0.6 10.4 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2828 PF11443.8 KFM74305.1 - 0.54 8.3 6.8 0.67 8.0 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NARP1 PF12569.8 KFM74305.1 - 0.62 8.9 12.8 0.76 8.6 12.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Tim54 PF11711.8 KFM74305.1 - 0.81 8.4 8.5 1 8.1 8.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FGF-BP1 PF06473.12 KFM74305.1 - 1.2 8.9 9.8 1.5 8.6 9.8 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) CDC45 PF02724.14 KFM74305.1 - 1.3 7.3 13.7 1.5 7.0 13.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 KFM74305.1 - 1.4 8.6 15.5 1.9 8.3 15.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 KFM74305.1 - 1.5 9.2 11.0 2.2 8.7 11.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RRN3 PF05327.11 KFM74305.1 - 1.7 7.1 7.8 2 6.9 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RP-C_C PF11800.8 KFM74305.1 - 2.6 8.1 5.4 3.3 7.7 5.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Sporozoite_P67 PF05642.11 KFM74305.1 - 3.1 5.8 12.1 3.8 5.5 12.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_S49_N PF08496.10 KFM74305.1 - 5.2 7.1 10.2 9.4 6.3 10.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMEM214 PF10151.9 KFM74305.1 - 7.9 4.8 13.4 9.1 4.6 13.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Cgr1 PF03879.14 KFM74308.1 - 3e-17 62.9 31.1 3.6e-17 62.7 31.1 1.0 1 0 0 1 1 1 1 Cgr1 family SPG4 PF17325.2 KFM74308.1 - 0.2 12.8 5.9 0.3 12.2 5.9 1.2 1 0 0 1 1 1 0 Stationary phase protein 4 Atrophin-1 PF03154.15 KFM74308.1 - 0.73 8.1 15.1 0.73 8.0 15.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family Auts2 PF15336.6 KFM74308.1 - 1.3 9.1 11.4 1.9 8.6 11.4 1.3 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Mem_trans PF03547.18 KFM74308.1 - 2.1 6.7 4.9 2.5 6.4 4.9 1.0 1 0 0 1 1 1 0 Membrane transport protein CSG2 PF16965.5 KFM74308.1 - 2.8 6.8 3.6 3.4 6.5 3.6 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator AAA_11 PF13086.6 KFM74308.1 - 3.7 7.3 14.0 4.5 7.0 14.0 1.0 1 0 0 1 1 1 0 AAA domain Peptidase_S49_N PF08496.10 KFM74308.1 - 5.3 7.1 11.5 7 6.7 11.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 KFM74308.1 - 7.1 6.4 12.4 8.1 6.2 12.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3732 PF12532.8 KFM74309.1 - 0.19 11.3 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) NPV_P10 PF05531.12 KFM74310.1 - 5.1e-05 23.7 5.9 0.0039 17.6 0.4 2.3 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.18 KFM74310.1 - 0.00045 20.2 1.8 0.0042 17.0 0.7 1.8 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 KFM74310.1 - 0.0068 16.4 3.4 0.0068 16.4 3.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 KFM74310.1 - 0.012 14.5 3.4 0.013 14.4 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KFM74310.1 - 0.025 15.0 9.7 0.068 13.6 1.9 3.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF1640 PF07798.11 KFM74310.1 - 0.026 14.6 2.9 0.033 14.3 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) WASH_WAHD PF11945.8 KFM74310.1 - 0.026 14.1 5.1 0.029 13.9 1.8 2.3 1 1 1 2 2 2 0 WAHD domain of WASH complex ABC_tran_CTD PF16326.5 KFM74310.1 - 0.03 14.6 0.3 0.03 14.6 0.3 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain CLZ PF16526.5 KFM74310.1 - 0.05 14.0 0.9 0.92 9.9 0.9 2.3 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5446 PF17522.2 KFM74310.1 - 0.076 13.2 0.4 0.076 13.2 0.4 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5446) DUF3584 PF12128.8 KFM74310.1 - 0.086 10.4 4.2 0.1 10.1 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KFM74310.1 - 0.092 12.8 0.3 0.26 11.3 0.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CALCOCO1 PF07888.11 KFM74310.1 - 0.1 11.4 4.5 0.13 11.1 4.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HSBP1 PF06825.12 KFM74310.1 - 0.11 12.4 0.4 2.4 8.1 0.1 2.6 1 1 3 4 4 4 0 Heat shock factor binding protein 1 Transcrip_act PF04949.13 KFM74310.1 - 0.11 12.4 6.0 0.76 9.6 6.0 1.9 1 1 0 1 1 1 0 Transcriptional activator LPP PF04728.13 KFM74310.1 - 0.17 12.3 6.9 14 6.1 1.2 3.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper ApoO PF09769.9 KFM74310.1 - 0.17 11.9 1.5 1.8 8.6 0.1 2.1 1 1 1 2 2 2 0 Apolipoprotein O COG2 PF06148.11 KFM74310.1 - 0.18 11.9 7.2 0.56 10.3 0.3 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.14 KFM74310.1 - 0.23 11.8 10.6 0.64 10.3 11.0 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KFM74310.1 - 0.24 10.7 3.8 0.29 10.4 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF148 PF02520.17 KFM74310.1 - 0.25 11.5 8.2 13 6.0 8.2 2.2 1 1 0 1 1 1 0 Domain of unknown function DUF148 DUF5082 PF16888.5 KFM74310.1 - 0.27 11.5 6.4 4.1 7.7 6.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 KFM74310.1 - 0.29 11.1 13.3 5.5 7.0 4.7 3.0 1 1 1 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.9 KFM74310.1 - 0.34 11.2 4.5 2.4 8.5 4.5 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KFM74310.1 - 0.36 11.0 5.2 0.27 11.4 3.5 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Dynamitin PF04912.14 KFM74310.1 - 0.53 9.5 7.5 1.5 8.1 2.2 2.2 1 1 1 2 2 2 0 Dynamitin DUF16 PF01519.16 KFM74310.1 - 0.6 10.6 9.8 36 4.9 8.7 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 ApoLp-III PF07464.11 KFM74310.1 - 0.63 10.1 9.1 1.8 8.6 9.1 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF730 PF05325.11 KFM74310.1 - 1.1 9.3 4.8 1.1 9.2 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Atg14 PF10186.9 KFM74310.1 - 1.2 8.1 4.7 1.5 7.8 4.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 KFM74310.1 - 1.4 9.2 5.9 11 6.4 0.4 3.1 2 1 0 2 2 2 0 TSC-22/dip/bun family Seryl_tRNA_N PF02403.22 KFM74310.1 - 3.4 7.9 12.3 1.7 8.9 1.6 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DDE_3 PF13358.6 KFM74311.1 - 1.3e-08 34.7 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FCH PF00611.23 KFM74312.1 - 3.4e-13 49.7 0.2 3.4e-13 49.7 0.2 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFM74312.1 - 3.4e-10 39.4 0.8 3.4e-10 39.4 0.8 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFM74312.1 - 5.7e-06 26.1 0.5 5.7e-06 26.1 0.5 2.3 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 KFM74312.1 - 0.0018 17.9 0.0 0.0048 16.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3BP5 PF05276.14 KFM74312.1 - 0.011 15.5 13.5 0.14 12.0 13.8 2.3 1 1 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF4407 PF14362.6 KFM74312.1 - 0.11 11.8 0.5 0.23 10.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LemA PF04011.12 KFM74312.1 - 0.19 11.6 3.5 0.66 9.8 3.5 2.0 1 1 0 1 1 1 0 LemA family FliJ PF02050.16 KFM74312.1 - 0.47 10.7 8.8 0.63 10.3 4.6 2.8 1 1 2 3 3 3 0 Flagellar FliJ protein DUF1664 PF07889.12 KFM74312.1 - 0.7 9.9 3.4 1.3 9.0 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 KFM74312.1 - 1.5 9.0 10.1 5.7 7.2 8.4 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PSII_Pbs27 PF13326.6 KFM74312.1 - 1.6 9.0 5.2 8.4 6.7 0.0 2.7 2 1 0 2 2 2 0 Photosystem II Pbs27 AcylCoA_dehyd_C PF12186.8 KFM74312.1 - 4.1 7.6 6.7 6.4 6.9 0.5 2.9 3 1 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal Acyl_transf_1 PF00698.21 KFM74313.1 - 4.1e-71 240.1 0.0 6.4e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 KFM74313.1 - 1.7e-64 217.9 0.0 2.8e-64 217.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFM74313.1 - 4.3e-43 147.3 0.0 7.8e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KFM74313.1 - 2.3e-37 127.6 0.0 6.1e-37 126.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFM74313.1 - 1.2e-29 103.0 0.0 7.1e-29 100.5 0.0 2.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thioesterase PF00975.20 KFM74313.1 - 2.8e-21 76.7 0.0 5.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain ADH_zinc_N_2 PF13602.6 KFM74313.1 - 3.8e-16 60.3 0.0 4e-15 57.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PS-DH PF14765.6 KFM74313.1 - 9.1e-16 57.9 0.0 2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.26 KFM74313.1 - 9.9e-15 54.7 0.0 4e-14 52.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFM74313.1 - 1.4e-07 31.1 0.0 4.7e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 KFM74313.1 - 5.8e-05 23.4 0.1 0.00017 21.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KFM74313.1 - 0.0014 18.1 0.1 0.0028 17.1 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.13 KFM74313.1 - 0.024 14.5 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short_C2 PF13561.6 KFM74313.1 - 0.049 13.2 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KFM74313.1 - 0.08 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HTH_Tnp_Tc3_2 PF01498.18 KFM74314.1 - 2.6e-16 59.6 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74314.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74314.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74314.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74314.1 - 1.8 9.3 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM74315.1 - 1.2e-13 51.1 0.4 2.8e-13 49.9 0.4 1.7 1 0 0 1 1 1 1 Transposase Band_7 PF01145.25 KFM74316.1 - 7.5e-32 110.8 0.3 1.1e-31 110.3 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFM74316.1 - 0.0029 17.4 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 KFM74316.1 - 0.066 13.6 0.8 0.17 12.3 0.6 1.8 1 1 0 1 1 1 0 Phage protein Gp68 Band_7 PF01145.25 KFM74317.1 - 1.3e-33 116.5 0.3 1.7e-33 116.1 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFM74317.1 - 0.0006 19.6 0.1 0.00086 19.1 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 KFM74317.1 - 0.0071 16.7 1.7 0.014 15.8 1.3 1.7 1 1 0 1 1 1 1 Phage protein Gp68 COLFI PF01410.18 KFM74318.1 - 1.1e-79 267.1 0.0 1.2e-79 266.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Collagen PF01391.18 KFM74319.1 - 8e-32 108.8 108.7 4.9e-10 39.0 29.0 4.0 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) Collagen PF01391.18 KFM74320.1 - 1e-67 223.8 265.0 1.6e-09 37.4 33.8 8.1 1 1 7 8 8 8 8 Collagen triple helix repeat (20 copies) Collagen PF01391.18 KFM74321.1 - 1.3e-36 124.2 115.1 3.6e-10 39.5 30.1 4.3 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 KFM74322.1 - 1.2e-29 101.8 88.0 2.6e-09 36.7 24.0 4.3 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Laminin_G_3 PF13385.6 KFM74322.1 - 6.4e-05 23.1 0.1 0.0001 22.5 0.1 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 KFM74322.1 - 0.00027 21.5 0.0 0.00048 20.7 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM74322.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain Glyco_trans_1_3 PF13528.6 KFM74323.1 - 0.072 12.3 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 SNF PF00209.18 KFM74324.1 - 1.7e-205 683.7 45.5 4.9e-205 682.1 45.5 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Gate PF07670.14 KFM74324.1 - 2.2 8.6 14.2 4.7 7.5 10.0 3.4 2 1 0 2 2 2 0 Nucleoside recognition SAM_2 PF07647.17 KFM74325.1 - 2.5e-23 81.9 0.4 1.6e-12 47.3 0.1 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM74325.1 - 1.5e-19 70.2 0.4 6.6e-12 45.7 0.1 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 KFM74325.1 - 3.4e-12 47.0 2.2 9.7e-12 45.5 0.0 2.8 2 0 0 2 2 2 1 TIR domain Arm PF00514.23 KFM74325.1 - 0.00015 21.6 0.6 1 9.5 0.1 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat SAM_3 PF18016.1 KFM74325.1 - 0.0035 17.1 0.1 0.088 12.6 0.0 3.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) V-ATPase_H_C PF11698.8 KFM74325.1 - 0.0036 17.4 0.2 2.4 8.3 0.1 3.2 3 0 0 3 3 3 2 V-ATPase subunit H NIF PF03031.18 KFM74325.1 - 0.049 13.4 0.4 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase DUF3881 PF12997.7 KFM74325.1 - 0.057 12.7 3.2 0.15 11.3 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) zf-HIT PF04438.16 KFM74326.1 - 1.5e-05 24.7 14.4 2.2e-05 24.2 14.4 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-met PF12874.7 KFM74326.1 - 4.8 7.7 10.8 21 5.7 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DEAD PF00270.29 KFM74328.1 - 8.3e-15 55.0 0.0 1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM74328.1 - 3.4e-14 53.2 0.1 4.6e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFM74328.1 - 0.0007 18.9 0.0 0.00092 18.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 KFM74328.1 - 0.038 13.7 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA PF00004.29 KFM74328.1 - 0.08 13.4 0.4 0.79 10.1 0.2 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribonuclease_3 PF00636.26 KFM74329.1 - 4.5e-37 126.9 3.3 2e-20 73.4 0.1 3.5 3 0 0 3 3 3 2 Ribonuclease III domain Dicer_dimer PF03368.14 KFM74329.1 - 6.1e-21 74.4 0.4 5.3e-20 71.4 0.1 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KFM74329.1 - 2.7e-20 72.8 0.2 5.6e-12 45.9 0.0 4.0 3 1 0 3 3 3 2 Ribonuclease-III-like PAZ PF02170.22 KFM74329.1 - 1.6e-19 70.0 5.2 4.3e-19 68.7 1.0 2.5 2 0 0 2 2 2 1 PAZ domain Helicase_C PF00271.31 KFM74329.1 - 1e-18 67.7 0.0 3.3e-18 66.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromosome_seg PF13889.6 KFM74331.1 - 3.2e-20 72.0 0.2 8.3e-20 70.7 0.2 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 KFM74331.1 - 1.3e-18 67.3 0.1 3.3e-18 66.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) DUF1959 PF09218.10 KFM74331.1 - 0.1 12.8 0.4 0.26 11.4 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) FAM178 PF14816.6 KFM74333.1 - 1 8.2 7.6 1 8.2 2.0 2.3 2 0 0 2 2 2 0 Family of unknown function, FAM178 TPH PF13868.6 KFM74333.1 - 9 4.7 41.6 3.6 6.0 9.1 3.1 3 0 0 3 3 3 0 Trichohyalin-plectin-homology domain Clat_adaptor_s PF01217.20 KFM74334.1 - 8.9e-53 178.0 3.0 1e-52 177.8 3.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CDO_I PF05995.12 KFM74335.1 - 1.2e-18 67.0 0.0 2.3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I DDE_1 PF03184.19 KFM74335.1 - 9.6e-12 44.9 0.0 2.1e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM74335.1 - 1.2e-11 44.4 0.8 2.6e-11 43.4 0.4 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM74335.1 - 0.0014 18.4 0.0 0.0068 16.2 0.0 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease ig PF00047.25 KFM74336.1 - 2.6e-09 37.1 0.1 6.4e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM74336.1 - 3.6e-08 33.6 0.1 1.1e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM74336.1 - 4.5e-08 33.6 0.3 1.7e-07 31.7 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Sushi PF00084.20 KFM74336.1 - 2.4e-07 31.2 1.8 1.7e-06 28.5 0.2 2.8 3 0 0 3 3 3 1 Sushi repeat (SCR repeat) Ig_2 PF13895.6 KFM74336.1 - 3.4e-06 27.3 0.0 1.5e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM74336.1 - 2.1e-05 24.5 0.0 4.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain C1-set PF07654.15 KFM74336.1 - 0.017 15.5 0.1 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFM74336.1 - 0.043 14.2 0.0 0.19 12.2 0.0 2.0 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain zf-H2C2_2 PF13465.6 KFM74337.1 - 6.3e-12 45.4 24.5 0.00031 21.0 0.3 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM74337.1 - 6.6e-10 39.0 22.1 0.004 17.9 1.8 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM74337.1 - 1.3e-09 38.0 23.7 0.00021 21.6 2.6 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.7 KFM74337.1 - 3.8e-06 27.1 16.5 0.0066 16.8 1.0 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.15 KFM74337.1 - 3.4e-05 23.8 4.4 0.092 12.8 0.0 3.6 3 1 1 4 4 4 2 Sec23/Sec24 zinc finger Zf_RING PF16744.5 KFM74337.1 - 0.0017 18.4 9.2 1.1 9.4 0.7 3.0 1 1 2 3 3 3 2 KIAA1045 RING finger DUF2256 PF10013.9 KFM74337.1 - 0.032 14.3 5.0 6.1 7.1 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_jaz PF12171.8 KFM74337.1 - 0.051 13.9 10.8 0.71 10.2 0.3 3.5 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.21 KFM74337.1 - 0.074 13.2 9.4 0.27 11.4 9.2 1.9 1 1 1 2 2 2 0 FYVE zinc finger zf-HIT PF04438.16 KFM74337.1 - 0.12 12.3 12.2 1.3 8.9 2.4 3.1 3 0 0 3 3 3 0 HIT zinc finger A2L_zn_ribbon PF08792.10 KFM74337.1 - 0.15 11.8 8.4 0.75 9.6 0.1 3.3 3 1 0 3 3 3 0 A2L zinc ribbon domain zf-C2H2_6 PF13912.6 KFM74337.1 - 0.16 12.0 0.3 0.16 12.0 0.3 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.12 KFM74337.1 - 0.25 11.6 13.2 1.6 9.0 12.9 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain zf-met2 PF12907.7 KFM74337.1 - 0.25 11.5 14.7 1.1 9.5 0.5 3.4 3 0 0 3 3 3 0 Zinc-binding XPA_N PF01286.18 KFM74337.1 - 0.26 11.4 3.4 17 5.5 0.1 2.9 3 0 0 3 3 3 0 XPA protein N-terminal zf-CCHC_2 PF13696.6 KFM74337.1 - 0.28 11.1 15.4 3 7.8 0.8 4.0 4 0 0 4 4 4 0 Zinc knuckle zf-MYST PF17772.1 KFM74337.1 - 0.28 10.8 13.2 0.28 10.8 0.2 3.0 1 1 2 3 3 3 0 MYST family zinc finger domain TRAF6_Z2 PF18048.1 KFM74337.1 - 0.3 11.2 10.3 3.5 7.8 0.1 3.2 3 1 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-trcl PF13451.6 KFM74337.1 - 0.58 10.1 6.1 5.7 6.9 0.1 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain Cas_CXXC_CXXC PF09706.10 KFM74337.1 - 0.91 9.8 8.6 4.4 7.6 0.4 3.1 1 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF4764 PF15961.5 KFM74337.1 - 1.9 7.1 4.7 2.9 6.5 4.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4764) Sulfatase PF00884.23 KFM74338.1 - 3.2e-78 263.3 0.0 4.7e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFM74338.1 - 7.6e-26 91.3 0.1 1.1e-25 90.7 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFM74338.1 - 0.00044 19.9 0.0 0.095 12.3 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase SAM_4 PF18017.1 KFM74339.1 - 9.7e-26 89.5 0.0 2.2e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5577 PF17740.1 KFM74339.1 - 6.5e-21 75.3 13.3 9.1e-21 74.8 13.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5577) SAM_1 PF00536.30 KFM74339.1 - 0.0066 16.9 0.0 0.029 14.8 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM74339.1 - 0.016 15.3 0.1 0.053 13.6 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Frag1 PF10277.9 KFM74340.1 - 4.2e-14 52.6 4.7 4.9e-14 52.4 4.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3437 PF11919.8 KFM74341.1 - 4.9e-35 119.3 0.0 3.2e-34 116.7 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KFM74341.1 - 0.00015 21.7 4.0 0.0066 16.6 0.0 4.7 4 1 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 KFM74341.1 - 0.021 14.4 0.6 0.041 13.4 0.6 1.5 1 0 0 1 1 1 0 CLASP N terminal HEAT_2 PF13646.6 KFM74341.1 - 0.1 13.0 0.1 2 8.9 0.1 2.8 2 1 1 3 3 3 0 HEAT repeats Vac14_Fab1_bd PF12755.7 KFM74341.1 - 0.13 12.9 0.0 6.5 7.4 0.1 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KFM74341.1 - 0.14 11.3 1.1 0.2 10.7 0.1 1.8 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Cupin_4 PF08007.12 KFM74342.1 - 1.1e-11 44.7 0.4 1.6e-11 44.3 0.0 1.4 2 0 0 2 2 2 1 Cupin superfamily protein Mei5 PF10376.9 KFM74342.1 - 0.13 12.1 4.8 0.19 11.6 4.8 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein PMP22_Claudin PF00822.20 KFM74342.1 - 0.28 11.0 0.2 1.3 8.9 0.1 2.0 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family 7tm_2 PF00002.24 KFM74343.1 - 2e-32 112.4 6.4 2.6e-32 112.1 6.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) FlaG PF03646.15 KFM74343.1 - 0.14 12.3 0.6 0.26 11.5 0.6 1.4 1 0 0 1 1 1 0 FlaG protein CrgA PF06781.12 KFM74343.1 - 0.42 10.7 2.8 0.28 11.3 0.5 2.0 2 0 0 2 2 2 0 Cell division protein CrgA DUF2304 PF10066.9 KFM74343.1 - 4.6 7.5 7.1 4.7 7.5 3.6 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Copper-bind PF00127.20 KFM74344.1 - 0.03 14.8 1.4 0.035 14.6 0.9 1.4 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Cadherin PF00028.17 KFM74346.1 - 2.9e-56 187.9 9.6 3.8e-19 68.9 0.5 5.6 5 0 0 5 5 5 5 Cadherin domain Laminin_G_2 PF02210.24 KFM74346.1 - 5.4e-53 178.9 0.8 1.5e-28 99.9 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain Cadherin_C PF01049.17 KFM74346.1 - 2.2e-52 177.2 0.0 4.4e-52 176.3 0.0 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_1 PF00054.23 KFM74346.1 - 2e-32 112.2 0.0 2.1e-20 73.3 0.0 2.5 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFM74346.1 - 1.4e-08 34.9 65.4 1.8e-06 28.1 9.5 5.2 5 0 0 5 5 5 3 EGF-like domain Laminin_G_3 PF13385.6 KFM74346.1 - 9.8e-06 25.8 0.0 0.032 14.4 0.0 2.9 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.15 KFM74346.1 - 0.0044 17.2 6.2 0.0044 17.2 6.2 6.5 5 1 0 5 5 4 1 Calcium-binding EGF domain hEGF PF12661.7 KFM74346.1 - 0.0077 16.8 8.5 0.0077 16.8 8.5 5.7 6 0 0 6 6 5 2 Human growth factor-like EGF EGF_2 PF07974.13 KFM74346.1 - 0.011 16.0 10.7 0.011 16.0 10.7 4.9 5 1 0 5 5 3 0 EGF-like domain TMEM154 PF15102.6 KFM74346.1 - 0.022 14.7 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 KFM74346.1 - 0.12 12.1 0.2 0.29 10.9 0.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DER1 PF04511.15 KFM74347.1 - 3.7e-63 212.9 17.5 4.2e-63 212.7 17.5 1.0 1 0 0 1 1 1 1 Der1-like family DDE_3 PF13358.6 KFM74348.1 - 4.2e-16 59.0 0.1 5.1e-15 55.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74348.1 - 7.1e-16 58.2 6.5 1.3e-15 57.4 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM74348.1 - 0.00065 20.3 1.5 0.00065 20.3 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM74348.1 - 0.002 17.9 0.1 0.11 12.4 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM74348.1 - 0.013 15.6 0.1 0.059 13.5 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM74348.1 - 0.025 14.6 2.4 0.032 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix PhoLip_ATPase_N PF16209.5 KFM74349.1 - 1.2e-27 95.4 5.0 1.9e-27 94.7 5.0 1.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KFM74349.1 - 7.3e-06 25.6 0.1 2.4e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Ribosomal_L27 PF01016.19 KFM74349.1 - 0.084 12.9 0.0 1.5 8.9 0.0 2.4 1 1 1 2 2 2 0 Ribosomal L27 protein PhoLip_ATPase_C PF16212.5 KFM74350.1 - 4.4e-40 138.0 12.4 6.2e-40 137.5 12.4 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 KFM74350.1 - 5.5e-11 42.4 0.0 8.7e-10 38.6 0.0 2.4 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFM74350.1 - 5.7e-10 39.8 1.2 0.0004 20.7 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM74350.1 - 0.0011 18.8 0.1 0.0036 17.1 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MIP-T3_C PF17749.1 KFM74351.1 - 9.9e-39 132.8 8.9 1.4e-38 132.3 8.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region CorA PF01544.18 KFM74351.1 - 0.13 11.6 4.1 0.17 11.2 4.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 KFM74351.1 - 1.2 9.3 6.7 1.1 9.5 5.1 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family zf-CpG_bind_C PF12269.8 KFM74351.1 - 1.8 8.3 5.8 0.25 11.1 1.4 1.7 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain LMBR1 PF04791.16 KFM74351.1 - 2.2 7.1 5.2 2.8 6.8 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein adh_short PF00106.25 KFM74352.1 - 1.3e-38 132.5 0.0 1.6e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM74352.1 - 6.3e-27 94.6 0.0 1.5e-26 93.4 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM74352.1 - 2.1e-08 34.3 0.0 3.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFM74352.1 - 1.5e-06 27.8 0.0 3.8e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) HIM1 PF08732.10 KFM74352.1 - 0.00027 20.5 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 HIM1 Ldl_recept_a PF00057.18 KFM74353.1 - 9.4e-86 281.7 171.8 1.3e-13 50.9 12.7 9.5 9 1 1 10 10 10 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFM74353.1 - 6.1e-39 132.2 6.6 5.9e-14 52.3 0.1 5.5 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFM74353.1 - 1.6e-20 73.1 38.6 2e-10 40.8 5.8 6.5 6 1 1 7 7 7 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFM74353.1 - 5.5e-13 48.6 21.8 2.4e-09 37.0 3.2 5.5 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_CA PF07645.15 KFM74353.1 - 1.6e-07 31.4 7.0 1.6e-07 31.4 7.0 11.8 6 3 2 8 8 8 2 Calcium-binding EGF domain SGL PF08450.12 KFM74353.1 - 1.4e-06 28.1 0.1 0.0037 16.9 0.0 3.2 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KFM74353.1 - 0.00032 20.8 0.1 0.16 12.2 0.0 3.6 4 1 0 4 4 4 1 Arylesterase DUF5050 PF16472.5 KFM74353.1 - 0.0036 16.6 0.0 0.011 15.0 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5050) EGF PF00008.27 KFM74353.1 - 0.025 14.9 6.5 0.025 14.9 6.5 10.1 10 1 0 10 10 10 0 EGF-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM74354.1 - 2.5e-16 59.7 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74354.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SWIB PF02201.18 KFM74355.1 - 8.3e-26 89.7 0.4 1.7e-25 88.7 0.2 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 KFM74355.1 - 1.8e-15 56.6 0.6 4.4e-15 55.3 0.6 1.7 1 0 0 1 1 1 1 DEK C terminal domain YL1 PF05764.13 KFM74355.1 - 0.051 13.7 20.2 0.074 13.2 20.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein AF-4 PF05110.13 KFM74355.1 - 0.093 10.8 26.4 0.14 10.3 26.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LAP1C PF05609.12 KFM74355.1 - 0.32 10.0 17.5 0.39 9.7 17.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 KFM74355.1 - 0.37 7.9 17.3 0.44 7.6 17.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 KFM74355.1 - 2.4 6.6 18.0 2.9 6.3 18.0 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 KFM74355.1 - 2.9 6.3 19.5 3.6 6.0 19.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 V_ATPase_I PF01496.19 KFM74355.1 - 4.4 5.1 7.2 5.5 4.8 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apt1 PF10351.9 KFM74355.1 - 6.4 5.5 22.4 9.1 5.0 22.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MULE PF10551.9 KFM74356.1 - 0.065 13.7 0.0 0.084 13.3 0.0 1.1 1 0 0 1 1 1 0 MULE transposase domain PhoLip_ATPase_N PF16209.5 KFM74359.1 - 8.4e-26 89.5 7.5 8.4e-26 89.5 7.5 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFM74359.1 - 5.5e-11 42.4 0.0 1.8e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFM74359.1 - 3.3e-07 30.0 0.0 1.3e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase BfiI_DBD PF18243.1 KFM74359.1 - 0.00019 21.1 0.1 0.00033 20.3 0.1 1.3 1 0 0 1 1 1 1 Metal-independent restriction enzyme BfiI DNA binding domain FimH_man-bind PF09160.10 KFM74359.1 - 0.11 12.2 0.1 17 5.1 0.0 2.3 2 0 0 2 2 2 0 FimH, mannose binding SecG PF03840.14 KFM74359.1 - 2.6 8.2 6.3 8 6.6 0.4 2.7 2 0 0 2 2 2 0 Preprotein translocase SecG subunit PhoLip_ATPase_C PF16212.5 KFM74360.1 - 3.9e-80 269.2 29.3 4.9e-80 268.9 29.3 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KFM74360.1 - 3.5e-07 30.7 0.0 0.012 15.9 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM74360.1 - 0.00088 19.1 0.1 0.0018 18.0 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF805 PF05656.14 KFM74361.1 - 0.42 11.0 0.1 0.42 11.0 0.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Mito_carr PF00153.27 KFM74362.1 - 2.1e-69 229.5 1.2 5.9e-23 80.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM74362.1 - 0.00058 19.1 0.3 6.5 5.8 0.0 3.3 2 1 1 3 3 3 3 Gammaproteobacterial serine protease DUF4519 PF15012.6 KFM74363.1 - 4.6e-22 77.9 2.6 5.3e-22 77.8 2.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF4448 PF14610.6 KFM74363.1 - 0.00014 21.7 0.0 0.00015 21.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) E1-E2_ATPase PF00122.20 KFM74363.1 - 0.0076 15.8 0.1 0.0082 15.7 0.1 1.0 1 0 0 1 1 1 1 E1-E2 ATPase DUF3671 PF12420.8 KFM74363.1 - 0.016 15.3 1.4 0.017 15.2 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF515 PF04415.12 KFM74363.1 - 0.017 13.5 1.3 0.017 13.6 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2207 PF09972.9 KFM74363.1 - 0.024 13.4 0.2 0.024 13.4 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 KFM74363.1 - 0.025 14.9 0.1 0.027 14.8 0.1 1.1 1 0 0 1 1 1 0 Orf78 (ac78) APG9 PF04109.16 KFM74363.1 - 0.044 12.8 0.4 0.043 12.8 0.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg9 TMEM154 PF15102.6 KFM74363.1 - 0.058 13.3 0.1 0.067 13.1 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family FeoB_associated PF12669.7 KFM74363.1 - 0.19 12.2 1.0 0.19 12.2 1.0 1.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Baculo_11_kDa PF06143.11 KFM74363.1 - 2.9 7.5 5.6 1.9 8.1 1.1 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family SKG6 PF08693.10 KFM74363.1 - 3.9 7.0 5.9 6.2 6.3 5.9 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEMspv1-c74-12 PF11044.8 KFM74363.1 - 8.6 6.4 14.4 1.4 9.0 1.3 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Fibrinogen_C PF00147.18 KFM74364.1 - 5.1e-61 206.3 6.2 7e-61 205.8 6.2 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Baculo_PEP_C PF04513.12 KFM74364.1 - 0.00052 20.1 14.4 0.041 13.9 0.1 4.0 3 1 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 KFM74364.1 - 0.0046 17.5 8.2 0.21 12.2 0.2 3.5 1 1 2 3 3 3 2 Syntaxin 6, N-terminal EspB PF05802.11 KFM74364.1 - 0.22 11.5 3.7 6.5 6.7 0.2 2.3 2 0 0 2 2 2 0 Enterobacterial EspB protein DUF1664 PF07889.12 KFM74364.1 - 0.29 11.2 13.7 6.2 6.9 0.1 4.4 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KFM74364.1 - 0.29 11.4 4.8 5.9 7.2 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) KIP1 PF07765.12 KFM74364.1 - 0.63 10.2 10.9 5.4 7.2 0.1 4.6 4 1 0 4 4 4 0 KIP1-like protein Apolipoprotein PF01442.18 KFM74364.1 - 0.72 9.7 5.5 54 3.6 5.0 2.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF5082 PF16888.5 KFM74364.1 - 1.6 9.0 13.0 0.96 9.7 0.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) YlqD PF11068.8 KFM74364.1 - 2.3 8.6 8.5 1.2 9.5 0.1 3.0 4 0 0 4 4 3 0 YlqD protein Fib_alpha PF08702.10 KFM74364.1 - 3.9 7.6 12.5 6.8 6.9 2.5 3.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DASH_Dad3 PF08656.10 KFM74364.1 - 4.3 7.5 11.5 45 4.2 0.2 3.7 2 1 1 3 3 3 0 DASH complex subunit Dad3 DUF3450 PF11932.8 KFM74364.1 - 9.9 5.4 8.8 2.3 7.5 3.4 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF2152 PF10222.9 KFM74365.1 - 1.8e-128 429.5 0.2 2e-128 429.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) Vps26 PF03643.15 KFM74367.1 - 3.1e-50 170.7 2.1 4.7e-50 170.1 2.1 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFM74367.1 - 3.2e-07 30.5 0.0 8.5e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFM74367.1 - 0.094 13.2 0.3 0.094 13.2 0.3 2.7 3 1 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain 7tm_1 PF00001.21 KFM74369.1 - 1.7e-31 109.5 5.8 1.8e-31 109.5 5.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFM74369.1 - 3.8e-05 23.2 3.3 4.4e-05 23.0 3.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFM74369.1 - 0.0018 18.1 5.6 0.0029 17.4 5.6 1.3 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFM74369.1 - 0.017 14.8 11.8 0.034 13.8 11.8 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF1761 PF08570.10 KFM74369.1 - 0.19 12.0 5.9 0.94 9.7 5.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) HTH_Tnp_Tc3_2 PF01498.18 KFM74370.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74370.1 - 9e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74371.1 - 1.9e-08 34.4 0.0 2e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Transposase Aminotran_1_2 PF00155.21 KFM74372.1 - 7.1e-15 55.0 0.0 8.7e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3432 PF11914.8 KFM74376.1 - 0.016 15.4 0.2 0.028 14.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) RRM_1 PF00076.22 KFM74377.1 - 1.7e-18 66.2 0.1 2.3e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFM74377.1 - 1.3e-06 28.2 4.7 2.8e-06 27.1 4.7 1.6 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 KFM74377.1 - 5.8e-06 25.9 0.0 8.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFM74377.1 - 9.3e-05 22.4 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Limkain b1 zf-CCHC_3 PF13917.6 KFM74377.1 - 0.00033 20.5 0.4 0.00074 19.4 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle RNA_bind PF08675.11 KFM74377.1 - 0.014 15.4 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain RRM_7 PF16367.5 KFM74377.1 - 0.019 15.1 0.0 0.052 13.7 0.0 1.8 1 1 1 2 2 2 0 RNA recognition motif DbpA PF03880.15 KFM74377.1 - 0.037 14.0 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 DbpA RNA binding domain zf-CCHC_5 PF14787.6 KFM74377.1 - 0.064 13.0 6.0 0.12 12.1 6.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KFM74377.1 - 0.076 12.8 4.8 0.14 12.0 4.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFM74377.1 - 0.11 12.2 0.3 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle RRM_occluded PF16842.5 KFM74377.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif UPF0113_N PF17833.1 KFM74378.1 - 5.4e-23 81.3 0.1 8.1e-23 80.8 0.1 1.5 1 1 0 1 1 1 1 UPF0113 Pre-PUA domain TcpS PF17456.2 KFM74378.1 - 0.46 10.5 3.3 0.94 9.5 2.3 1.8 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S Laminin_G_2 PF02210.24 KFM74379.1 - 2.1e-23 83.2 0.0 2.8e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM74379.1 - 4.3e-23 82.0 0.0 5.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFM74379.1 - 0.00049 20.3 0.1 0.00065 19.9 0.1 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Dimer_Tnp_hAT PF05699.14 KFM74380.1 - 1.5e-11 43.9 0.0 3.7e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KFM74380.1 - 4.8e-07 29.7 1.0 0.0076 16.1 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Propep_M14 PF02244.16 KFM74380.1 - 1.4 9.3 4.8 4.2 7.8 0.7 3.1 4 0 0 4 4 4 0 Carboxypeptidase activation peptide I-set PF07679.16 KFM74381.1 - 1.4e-08 34.7 0.1 2.2e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM74381.1 - 2e-08 34.3 0.1 3.7e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ldl_recept_a PF00057.18 KFM74381.1 - 3e-08 33.8 4.4 3e-08 33.8 4.4 2.8 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Ig_3 PF13927.6 KFM74381.1 - 8.2e-08 32.8 0.1 1.4e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM74381.1 - 4.5e-07 30.0 0.4 0.0011 19.2 0.0 2.4 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM74381.1 - 1e-05 25.8 0.1 1.9e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFM74381.1 - 0.00068 19.1 0.2 0.0018 17.8 0.2 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM74381.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.6 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain DUF692 PF05114.13 KFM74381.1 - 0.084 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF692) Ku_N PF03731.15 KFM74382.1 - 1.2e-49 169.1 0.8 2e-49 168.3 0.8 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 KFM74382.1 - 2.2e-43 148.4 0.1 4.5e-43 147.3 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 KFM74382.1 - 4.2e-19 69.0 0.3 1.8e-18 67.0 0.1 2.2 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Rho_N PF07498.12 KFM74382.1 - 0.04 13.9 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain VWA PF00092.28 KFM74382.1 - 0.12 12.7 0.1 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain AAA_25 PF13481.6 KFM74383.1 - 1.4e-20 73.7 0.0 2.3e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KFM74383.1 - 2.4e-09 36.9 0.0 4.7e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 KFM74383.1 - 3.2e-07 30.0 0.0 9.5e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 KFM74383.1 - 2.1e-06 28.1 0.0 4.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM74383.1 - 0.014 15.7 0.0 0.025 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFM74383.1 - 0.037 13.8 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KFM74383.1 - 0.077 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KFM74383.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFM74383.1 - 0.09 12.3 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KFM74383.1 - 0.1 13.1 0.2 0.23 12.0 0.2 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM74383.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase DUF1712 PF08217.11 KFM74384.1 - 1.4e-69 235.2 17.6 4.3e-62 210.5 11.8 3.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) HisK_N PF09385.10 KFM74384.1 - 0.043 13.8 0.3 0.13 12.2 0.3 1.8 1 0 0 1 1 1 0 Histidine kinase N terminal TetR_C_19 PF17924.1 KFM74384.1 - 0.46 11.1 6.1 0.15 12.7 1.5 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Thioredoxin PF00085.20 KFM74385.1 - 9.8e-28 96.2 0.2 1.3e-27 95.8 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KFM74385.1 - 1e-06 28.8 0.1 1.8e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFM74385.1 - 6.5e-06 26.6 0.1 0.00022 21.7 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KFM74385.1 - 4.8e-05 22.9 0.1 5.9e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KFM74385.1 - 0.00013 21.7 0.1 0.00017 21.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 KFM74385.1 - 0.00027 21.3 0.0 0.00053 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_8 PF13905.6 KFM74385.1 - 0.0006 20.1 0.0 0.11 12.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.6 KFM74385.1 - 0.001 19.1 0.1 0.0029 17.6 0.1 1.7 1 1 1 2 2 2 1 Thioredoxin domain DSBA PF01323.20 KFM74385.1 - 0.028 14.2 0.1 1.1 8.9 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Herpes_TK PF00693.18 KFM74385.1 - 0.039 13.2 0.0 0.043 13.0 0.0 1.1 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus RVT_1 PF00078.27 KFM74386.1 - 8.6e-11 41.8 0.0 8.8e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.18 KFM74387.1 - 4.5e-16 58.8 3.5 6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74387.1 - 3.4e-12 46.3 0.0 5.9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74387.1 - 2.2e-07 30.5 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74387.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74387.1 - 2.2 9.0 15.6 0.13 12.9 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain Aminotran_1_2 PF00155.21 KFM74388.1 - 8.7e-85 285.1 0.0 9.8e-85 284.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II UPF0449 PF15136.6 KFM74388.1 - 0.22 12.0 0.0 12 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Ndr PF03096.14 KFM74389.1 - 7.6e-96 320.1 0.5 9.4e-96 319.8 0.5 1.0 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 KFM74389.1 - 0.014 14.7 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Mei4 PF13971.6 KFM74389.1 - 0.026 14.0 0.2 0.05 13.1 0.2 1.4 1 1 0 1 1 1 0 Meiosis-specific protein Mei4 Abhydrolase_1 PF00561.20 KFM74389.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold PsiA PF06952.11 KFM74389.1 - 0.088 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 PsiA protein VCBS PF13517.6 KFM74390.1 - 2e-05 25.1 1.4 0.0036 17.9 0.4 3.2 2 1 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.6 KFM74390.1 - 0.0026 17.4 0.0 0.32 10.6 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 KFM74390.1 - 0.011 16.1 0.0 2 9.0 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain TMEM132D_C PF15706.5 KFM74390.1 - 0.026 14.3 0.4 0.061 13.1 0.4 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term FG-GAP PF01839.23 KFM74390.1 - 0.14 12.4 2.2 2 8.6 0.8 2.5 2 0 0 2 2 2 0 FG-GAP repeat Cyclin PF08613.11 KFM74391.1 - 3e-09 37.5 0.1 7.3e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFM74391.1 - 1.1e-05 25.2 0.2 2.4e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4371 PF14291.6 KFM74392.1 - 1.3e-32 113.4 1.1 2.9e-32 112.2 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) RVT_2 PF07727.14 KFM74392.1 - 5.2e-08 32.8 0.2 1.4e-07 31.4 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UreE_N PF02814.15 KFM74392.1 - 0.047 13.3 0.3 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain bPH_4 PF06713.11 KFM74392.1 - 0.055 13.6 0.0 0.23 11.5 0.0 2.1 1 0 0 1 1 1 0 Bacterial PH domain zf-CCHC_2 PF13696.6 KFM74392.1 - 0.06 13.2 4.9 0.14 12.0 4.9 1.7 1 0 0 1 1 1 0 Zinc knuckle BIR PF00653.21 KFM74392.1 - 1.2 9.9 6.0 5.6 7.7 0.3 3.5 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain DUF1216 PF06746.11 KFM74392.1 - 7 6.7 7.4 0.35 10.9 0.1 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1216) PDH PF02153.17 KFM74393.1 - 0.00024 20.2 13.3 1.3 8.0 0.1 5.3 2 2 2 4 4 4 4 Prephenate dehydrogenase RNase_PH PF01138.21 KFM74393.1 - 0.00033 21.2 1.3 1.4 9.4 0.1 3.0 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 PRO8NT PF08082.11 KFM74393.1 - 0.026 14.5 2.9 5.4 6.9 0.2 2.8 2 0 0 2 2 2 0 PRO8NT (NUC069), PrP8 N-terminal domain Rot1 PF10681.9 KFM74393.1 - 0.029 13.9 8.8 0.85 9.1 0.0 3.3 4 0 0 4 4 4 0 Chaperone for protein-folding within the ER, fungal MAT1-1-2 PF17043.5 KFM74393.1 - 0.066 13.1 3.0 10 6.0 0.1 3.2 2 2 0 2 2 2 0 Mating type protein 1-1-2 of unknown function Peptidase_M99 PF17033.5 KFM74393.1 - 0.082 12.3 10.9 3.6 6.9 0.6 3.5 2 1 1 3 3 3 0 Carboxypeptidase controlling helical cell shape catalytic NUDIX_2 PF13869.6 KFM74393.1 - 0.093 12.3 4.2 5.7 6.5 0.3 2.8 2 0 0 2 2 2 0 Nucleotide hydrolase EIID-AGA PF03613.14 KFM74393.1 - 0.25 10.5 1.3 16 4.5 0.1 2.3 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component GF_recep_IV PF14843.6 KFM74393.1 - 4.4 7.1 30.8 3.3 7.5 2.3 4.0 2 1 1 3 3 3 0 Growth factor receptor domain IV Haspin_kinase PF12330.8 KFM74394.1 - 0.00014 21.0 0.0 0.00015 20.8 0.0 1.0 1 0 0 1 1 1 1 Haspin like kinase domain Polo_box_2 PF18531.1 KFM74394.1 - 0.021 15.0 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Polo box domain DUF1759 PF03564.15 KFM74395.1 - 0.037 14.0 0.0 0.077 12.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) FMN_dh PF01070.18 KFM74396.1 - 9e-98 327.5 0.0 2.1e-97 326.3 0.0 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFM74396.1 - 1.1e-07 31.2 0.3 5e-07 29.0 0.1 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFM74396.1 - 5.4e-06 25.8 0.0 9.4e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DUF1943 PF09172.11 KFM74396.1 - 0.0036 16.6 1.4 0.017 14.4 1.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1943) Porin_3 PF01459.22 KFM74396.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic porin MspA PF09203.11 KFM74396.1 - 0.25 11.2 10.4 5.8 6.7 1.7 3.9 3 1 1 4 4 4 0 MspA zf-H2C2_2 PF13465.6 KFM74397.1 - 1.2e-49 164.5 51.7 1.1e-08 35.1 0.4 8.1 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74397.1 - 5.6e-36 121.0 64.0 4.2e-06 26.9 2.8 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-met PF12874.7 KFM74397.1 - 2.9e-25 87.9 60.1 0.00018 21.8 1.1 8.2 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM74397.1 - 1e-23 81.9 58.9 0.0012 19.4 0.9 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74397.1 - 1.6e-14 53.8 37.5 0.075 13.3 0.9 8.4 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM74397.1 - 1.3e-08 34.6 49.5 0.085 12.9 0.8 8.3 8 0 0 8 8 8 6 C2H2-type zinc finger BolA PF01722.18 KFM74397.1 - 3e-08 33.8 6.7 0.045 14.0 0.3 4.9 1 1 4 5 5 5 2 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM74397.1 - 1.8e-05 24.7 32.2 0.045 13.8 0.1 7.2 4 3 3 7 7 7 2 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM74397.1 - 9.8e-05 22.3 24.4 0.12 12.4 1.0 5.1 4 1 0 5 5 5 3 Adenylate kinase, active site lid zf-RRPl_C4 PF17026.5 KFM74397.1 - 0.00013 22.0 29.1 0.069 13.3 7.0 3.3 1 1 2 3 3 3 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_9 PF16293.5 KFM74397.1 - 0.00021 21.1 35.4 0.29 11.0 0.2 7.0 1 1 6 7 7 7 3 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFM74397.1 - 0.0015 18.3 34.9 0.45 10.3 0.2 7.0 7 0 0 7 7 7 4 zinc-finger C2H2-type DUF2256 PF10013.9 KFM74397.1 - 0.0086 16.2 30.4 1.5 9.0 0.3 8.0 7 1 1 8 8 8 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-CHCC PF10276.9 KFM74397.1 - 0.0099 15.9 10.8 80 3.4 0.0 7.1 8 0 0 8 8 8 0 Zinc-finger domain zf-DBF PF07535.12 KFM74397.1 - 0.012 15.7 28.1 7.2 6.8 0.3 7.0 7 0 0 7 7 7 0 DBF zinc finger zf-C2HC_2 PF13913.6 KFM74397.1 - 0.17 11.8 26.7 21 5.2 0.0 8.0 8 0 0 8 8 8 0 zinc-finger of a C2HC-type GAGA PF09237.11 KFM74397.1 - 0.23 11.3 16.0 5.2 6.9 0.1 6.0 1 1 7 8 8 8 0 GAGA factor TRAF6_Z2 PF18048.1 KFM74397.1 - 0.28 11.3 32.3 4.8 7.4 0.3 7.1 7 0 0 7 7 7 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_15 PF17032.5 KFM74397.1 - 0.79 10.5 30.0 1.6 9.5 2.1 4.4 1 1 4 5 5 5 0 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM74397.1 - 0.94 9.9 51.4 3 8.2 0.4 7.1 1 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) Cas_CXXC_CXXC PF09706.10 KFM74397.1 - 5.7 7.2 30.0 2.9 8.2 0.4 7.4 2 2 5 7 7 7 0 CRISPR-associated protein (Cas_CXXC_CXXC) PHF5 PF03660.14 KFM74397.1 - 8.9 6.6 22.4 0.95 9.7 3.0 3.9 1 1 3 4 4 4 0 PHF5-like protein zf-H2C2_2 PF13465.6 KFM74398.1 - 2.1e-63 208.1 58.6 1.2e-07 31.8 0.4 10.2 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74398.1 - 1.7e-39 132.1 74.9 6.9e-06 26.2 0.9 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74398.1 - 3.5e-30 102.1 71.9 0.00032 21.3 0.6 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM74398.1 - 4.4e-20 71.2 56.1 0.0037 17.2 0.7 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM74398.1 - 1.5e-11 44.2 66.4 0.0092 16.3 1.7 9.1 9 0 0 9 9 9 6 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM74398.1 - 2.2e-11 43.3 47.2 0.25 11.1 0.1 9.7 10 0 0 10 10 10 6 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM74398.1 - 4e-10 39.7 51.2 0.035 14.4 0.3 9.3 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM74398.1 - 1.6e-08 34.2 38.0 0.036 13.9 0.1 8.8 2 1 7 9 9 9 3 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM74398.1 - 1.1e-06 28.3 25.2 0.49 10.2 0.0 7.8 1 1 8 9 9 9 3 GAGA factor zf-C2H2_2 PF12756.7 KFM74398.1 - 0.00048 20.4 59.8 0.72 10.2 1.5 8.9 1 1 8 9 9 9 4 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM74398.1 - 0.0012 18.9 35.0 1.1 9.4 13.2 4.1 1 1 2 3 3 3 3 Putative ribonucleoprotein zinc-finger pf C4 type Tox-HNH-HHH PF15637.6 KFM74398.1 - 0.0018 18.4 3.4 9.6 6.4 0.1 4.2 1 1 3 6 6 6 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-CHCC PF10276.9 KFM74398.1 - 0.012 15.6 11.4 26 5.0 0.0 7.5 9 0 0 9 9 9 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KFM74398.1 - 0.014 15.3 35.6 4.6 7.3 0.1 8.2 8 1 0 8 8 8 0 zinc-finger of a C2HC-type Ndufs5 PF10200.9 KFM74398.1 - 0.017 15.4 8.7 4.5 7.6 0.5 5.3 1 1 3 5 5 5 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa BolA PF01722.18 KFM74398.1 - 0.021 15.1 15.8 3.7 7.9 0.3 5.5 1 1 5 6 6 6 0 BolA-like protein HNH_5 PF14279.6 KFM74398.1 - 0.026 14.4 34.3 2.1 8.3 0.8 7.0 4 3 2 6 6 6 0 HNH endonuclease DUF2256 PF10013.9 KFM74398.1 - 0.08 13.1 37.7 11 6.3 0.2 8.8 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) Alk_phosphatase PF00245.20 KFM74398.1 - 0.082 11.8 0.2 2.4 7.0 0.1 2.2 2 1 0 2 2 2 0 Alkaline phosphatase zinc_ribbon_15 PF17032.5 KFM74398.1 - 0.13 13.0 34.2 4.6 8.1 1.2 4.8 2 1 3 6 6 6 0 zinc-ribbon family Ribosomal_L35p PF01632.19 KFM74398.1 - 0.15 12.6 11.5 29 5.3 0.0 5.6 1 1 5 6 6 6 0 Ribosomal protein L35 ADK_lid PF05191.14 KFM74398.1 - 0.19 11.7 32.3 0.77 9.8 0.4 6.3 2 1 5 7 7 7 0 Adenylate kinase, active site lid C1_1 PF00130.22 KFM74398.1 - 0.35 10.8 48.6 4.6 7.2 2.0 8.3 3 2 4 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 KFM74398.1 - 1.4 9.1 48.1 20 5.4 8.7 5.1 1 1 3 4 4 3 0 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 KFM74398.1 - 1.8 8.7 33.8 5.6 7.1 0.4 8.6 5 2 3 9 9 9 0 Sec23/Sec24 zinc finger zf-HC3 PF16827.5 KFM74398.1 - 2 8.7 13.4 22 5.4 0.1 6.2 8 0 0 8 8 8 0 zinc-finger Ras PF00071.22 KFM74399.1 - 3.5e-37 127.5 0.0 4.4e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM74399.1 - 3.8e-15 56.2 0.0 5.1e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM74399.1 - 1.5e-07 31.0 0.0 1.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM74399.1 - 0.00087 18.9 0.0 0.0041 16.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM74399.1 - 0.0031 17.4 0.0 0.79 9.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFM74399.1 - 0.0079 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KFM74399.1 - 0.015 15.1 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.20 KFM74399.1 - 0.05 12.8 0.0 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 KFM74399.1 - 0.063 13.5 0.5 1.6 9.0 0.5 2.6 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFM74399.1 - 0.08 12.6 0.3 0.2 11.4 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM74399.1 - 0.095 13.1 0.0 0.14 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain BAR PF03114.18 KFM74401.1 - 1.1e-70 238.0 9.0 1.3e-70 237.7 9.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFM74401.1 - 3.8e-15 55.2 0.2 7.7e-15 54.2 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFM74401.1 - 3.9e-15 55.4 0.0 7.1e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFM74401.1 - 3.2e-12 46.2 9.4 2.8e-09 36.5 3.7 2.1 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_2 PF07653.17 KFM74401.1 - 6.3e-11 41.8 0.0 1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KFM74401.1 - 5.2e-05 23.1 4.6 0.00015 21.6 4.0 1.9 1 1 1 2 2 2 1 BAR domain of APPL family Coatomer_WDAD PF04053.14 KFM74401.1 - 0.071 12.1 0.7 0.094 11.7 0.7 1.1 1 0 0 1 1 1 0 Coatomer WD associated region TraG_N PF07916.11 KFM74401.1 - 0.27 10.0 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region tRNA-synt_2b PF00587.25 KFM74402.1 - 4.2e-36 124.6 0.0 9.4e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TGS PF02824.21 KFM74402.1 - 1.5e-16 60.2 0.0 3.6e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 TGS domain HGTP_anticodon PF03129.20 KFM74402.1 - 4.3e-14 52.4 0.0 1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KFM74402.1 - 2.3e-12 46.8 0.0 5.6e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain YscW PF09619.10 KFM74402.1 - 0.15 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) Na_Ca_ex PF01699.24 KFM74403.1 - 1.3e-55 187.5 46.0 5.2e-28 97.9 23.4 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Sulfotransfer_1 PF00685.27 KFM74404.1 - 3.5e-51 174.2 1.0 2.2e-49 168.3 1.0 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM74404.1 - 4.4e-09 37.0 0.0 1.6e-06 28.7 0.0 2.2 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM74405.1 - 4.6e-49 167.3 0.0 8.1e-49 166.5 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM74405.1 - 2.5e-09 37.8 0.0 6.6e-06 26.7 0.0 2.2 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFM74405.1 - 0.0073 16.2 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM74406.1 - 1.5e-36 126.2 0.0 2e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM74406.1 - 3.1e-05 24.5 0.1 0.044 14.2 0.1 2.1 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM74407.1 - 2.5e-47 161.6 0.3 4.9e-47 160.7 0.3 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM74407.1 - 2.5e-05 24.8 0.0 0.22 11.9 0.0 2.5 2 0 0 2 2 2 2 Sulfotransferase family DDE_Tnp_4 PF13359.6 KFM74408.1 - 9.3e-38 129.4 0.0 1.6e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease THAP PF05485.12 KFM74408.1 - 1.8e-18 67.2 7.0 4.7e-18 65.9 7.0 1.8 1 0 0 1 1 1 1 THAP domain HTH_Tnp_4 PF13613.6 KFM74408.1 - 1.1e-11 44.2 0.0 2.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KFM74408.1 - 6e-07 29.3 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain CAP_GLY PF01302.25 KFM74409.1 - 1.7e-45 152.8 2.1 1.2e-22 79.7 0.1 2.3 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 KFM74409.1 - 1.3e-07 31.3 6.0 2.5e-07 30.4 6.0 1.5 1 0 0 1 1 1 1 CLIP1 zinc knuckle GCD14_N PF14801.6 KFM74409.1 - 0.007 16.2 0.2 0.042 13.7 0.0 2.5 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term ATG16 PF08614.11 KFM74409.1 - 0.0081 16.4 33.1 0.0081 16.4 33.1 6.1 1 1 5 6 6 6 3 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KFM74409.1 - 0.081 12.9 160.4 0.089 12.8 10.9 8.7 2 2 6 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 p450 PF00067.22 KFM74410.1 - 4.3e-37 127.9 0.8 5.2e-37 127.7 0.8 1.0 1 0 0 1 1 1 1 Cytochrome P450 XRCC1_N PF01834.16 KFM74411.1 - 1.9e-63 212.9 1.5 3.2e-63 212.2 0.1 2.1 2 0 0 2 2 2 1 XRCC1 N terminal domain BRCT_2 PF16589.5 KFM74411.1 - 1.8e-25 89.2 3.6 3.3e-17 62.7 0.2 3.1 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFM74411.1 - 7.2e-23 80.8 0.3 7.1e-13 48.7 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFM74411.1 - 4.2e-13 49.0 0.0 1.1e-11 44.5 0.0 2.5 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 KFM74411.1 - 1.3e-09 38.2 0.1 3.2e-06 27.3 0.1 2.9 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KFM74411.1 - 1.7e-05 24.6 0.1 0.00065 19.5 0.0 2.6 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain 7tm_1 PF00001.21 KFM74412.1 - 8.2e-22 77.8 0.0 1.6e-21 76.8 0.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4448 PF14610.6 KFM74412.1 - 0.02 14.7 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) 7TM_GPCR_Srsx PF10320.9 KFM74412.1 - 0.061 12.7 0.2 0.081 12.3 0.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx ERO1 PF04137.15 KFM74413.1 - 6.5e-17 61.7 0.2 7.7e-17 61.5 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) NitrOD1 PF18549.1 KFM74413.1 - 0.13 12.3 0.7 0.22 11.5 0.7 1.4 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 DUF4760 PF15956.5 KFM74414.1 - 0.031 14.4 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) ARID PF01388.21 KFM74415.1 - 3.8e-19 69.2 0.1 1.4e-18 67.3 0.1 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DDE_1 PF03184.19 KFM74416.1 - 1.2e-17 64.2 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ErmC PF06308.11 KFM74416.1 - 0.019 15.3 0.2 0.04 14.3 0.2 1.4 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) AcetylCoA_hydro PF02550.15 KFM74416.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain MFS_1 PF07690.16 KFM74418.1 - 2e-13 50.0 17.3 2.9e-13 49.5 17.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3671 PF12420.8 KFM74418.1 - 8 6.6 7.6 1.6 8.8 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function Lebercilin PF15619.6 KFM74421.1 - 0.011 15.4 22.3 0.041 13.5 22.1 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease BSP PF04450.12 KFM74421.1 - 0.02 14.7 0.1 0.038 13.8 0.1 1.4 1 1 0 1 1 1 0 Peptidase of plants and bacteria HR1 PF02185.16 KFM74421.1 - 0.035 14.2 18.9 0.14 12.3 5.5 2.6 2 1 0 2 2 2 0 Hr1 repeat Csm1_N PF18504.1 KFM74421.1 - 0.039 14.3 3.8 0.039 14.3 3.8 2.8 3 0 0 3 3 3 0 Csm1 N-terminal domain NPV_P10 PF05531.12 KFM74421.1 - 0.089 13.3 5.4 0.77 10.3 1.7 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 KFM74421.1 - 0.11 11.8 11.3 0.074 12.3 9.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DASH_Dad4 PF08650.10 KFM74421.1 - 0.11 12.5 4.8 0.12 12.3 1.3 2.5 1 1 0 2 2 2 0 DASH complex subunit Dad4 DUF3053 PF11254.8 KFM74421.1 - 0.31 10.6 6.1 0.28 10.8 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) CC2-LZ PF16516.5 KFM74421.1 - 0.35 11.3 16.8 0.95 9.9 5.9 2.5 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF641 PF04859.12 KFM74421.1 - 0.54 10.6 19.0 0.55 10.6 6.6 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FapA PF03961.13 KFM74421.1 - 1.1 7.7 15.1 1.7 7.2 15.0 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A P4Ha_N PF08336.11 KFM74421.1 - 1.4 8.9 14.8 0.045 13.8 3.8 2.4 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TolA_bind_tri PF16331.5 KFM74421.1 - 1.4 9.0 13.1 0.067 13.3 3.2 2.8 1 1 2 3 3 3 0 TolA binding protein trimerisation Sec2p PF06428.11 KFM74421.1 - 1.5 8.9 21.0 4.6 7.3 4.8 2.6 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p PCRF PF03462.18 KFM74421.1 - 1.6 8.6 11.4 2 8.2 10.6 1.6 1 1 0 1 1 1 0 PCRF domain DUF4407 PF14362.6 KFM74421.1 - 2 7.7 9.4 2.4 7.4 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1635 PF07795.11 KFM74421.1 - 2.1 8.1 15.5 8.2 6.2 15.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) V_ATPase_I PF01496.19 KFM74421.1 - 2.2 6.1 12.7 2.7 5.8 12.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KFM74421.1 - 2.6 8.1 9.0 5.9 7.0 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF5320 PF17253.2 KFM74421.1 - 2.7 9.1 9.3 0.23 12.5 2.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) BST2 PF16716.5 KFM74421.1 - 3.4 8.3 17.1 8.2 7.1 10.0 2.6 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 CENP-H PF05837.12 KFM74421.1 - 4.6 7.7 17.5 0.41 11.1 11.5 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.15 KFM74421.1 - 5.3 6.5 11.6 7.7 6.0 11.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliD_N PF02465.18 KFM74421.1 - 5.4 7.8 13.2 11 6.7 2.0 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus OmpH PF03938.14 KFM74421.1 - 6 7.2 19.2 0.5 10.7 2.9 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) YabA PF06156.13 KFM74421.1 - 6.5 7.5 18.5 2.4 8.8 4.3 2.7 1 1 2 3 3 3 0 Initiation control protein YabA Atg14 PF10186.9 KFM74421.1 - 7.9 5.5 18.6 3.5 6.6 16.3 1.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med4 PF10018.9 KFM74421.1 - 8.5 6.0 14.6 1.3e+02 2.1 14.6 2.2 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4404 PF14357.6 KFM74421.1 - 9.6 6.9 15.7 3.8 8.2 2.8 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4404) Sulfotransfer_1 PF00685.27 KFM74422.1 - 7.5e-77 258.4 0.6 1e-76 257.9 0.6 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM74422.1 - 5.2e-12 46.6 0.0 1.6e-08 35.2 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family CFAP91 PF14738.6 KFM74426.1 - 0.0022 18.1 0.1 0.0033 17.5 0.1 1.3 1 0 0 1 1 1 1 Cilia- and flagella-associated protein 91 DUF720 PF05302.11 KFM74426.1 - 0.0033 17.3 0.4 0.0058 16.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF720) zf-CCCH_7 PF18586.1 KFM74426.1 - 0.063 13.6 0.8 0.24 11.8 0.3 2.2 1 1 2 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 SprT-like PF10263.9 KFM74427.1 - 8.8e-26 90.0 0.9 1.5e-25 89.2 0.2 1.7 2 0 0 2 2 2 1 SprT-like family Aminopep PF10023.9 KFM74427.1 - 0.094 12.1 3.0 6.6 6.0 0.0 2.4 2 1 0 2 2 2 0 Putative aminopeptidase BNIP2 PF12496.8 KFM74427.1 - 0.49 10.8 3.4 0.78 10.2 3.4 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 YfhD PF14151.6 KFM74427.1 - 3.8 7.7 5.9 6.1 7.1 0.7 2.6 1 1 1 2 2 2 0 YfhD-like protein NinF PF05810.12 KFM74427.1 - 5.2 7.0 7.0 1.1 9.2 0.5 2.8 3 0 0 3 3 3 0 NinF protein Trypsin PF00089.26 KFM74428.1 - 1.3e-59 201.7 0.0 1.8e-59 201.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFM74428.1 - 2.5e-17 63.2 0.0 4.2e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 CUB domain Trypsin_2 PF13365.6 KFM74428.1 - 4.6e-07 30.8 0.0 8.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ldl_recept_a PF00057.18 KFM74428.1 - 2.9e-06 27.4 10.1 6.1e-06 26.4 10.1 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 KFM74428.1 - 4.9e-06 26.9 0.1 8.6e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Peptidase_A17 PF05380.13 KFM74429.1 - 8e-34 117.0 4.4 2.6e-21 76.3 0.6 2.9 2 1 1 3 3 3 2 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 KFM74429.1 - 2.6e-11 43.5 4.0 3.8e-11 42.9 0.6 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM74429.1 - 8e-05 22.8 0.2 0.00029 21.0 0.2 2.0 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 KFM74429.1 - 0.00016 21.3 0.0 0.00052 19.6 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 KFM74429.1 - 0.013 15.3 0.7 0.034 14.0 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KFM74429.1 - 0.62 10.2 2.2 0.58 10.3 0.1 2.1 2 0 0 2 2 2 0 Zinc knuckle 5-FTHF_cyc-lig PF01812.20 KFM74430.1 - 2e-31 109.3 0.0 2.2e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family GYF PF02213.16 KFM74431.1 - 6.9e-14 51.3 4.9 8.1e-14 51.0 2.9 2.2 2 0 0 2 2 2 1 GYF domain Carb_anhydrase PF00194.21 KFM74432.1 - 6.2e-102 340.5 0.1 7.2e-102 340.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KFM74434.1 - 1.2e-91 306.7 0.0 1.4e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MFS_1 PF07690.16 KFM74436.1 - 2.1e-19 69.7 25.9 2.1e-19 69.7 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPP1 PF10341.9 KFM74436.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD PAN_1 PF00024.26 KFM74437.1 - 5.6e-19 67.9 27.3 2.6e-11 43.3 2.0 4.4 5 0 0 5 5 5 3 PAN domain PAN_2 PF08276.11 KFM74437.1 - 0.0015 18.6 11.5 0.017 15.3 0.1 3.8 4 0 0 4 4 4 2 PAN-like domain PAN_4 PF14295.6 KFM74437.1 - 0.069 13.1 0.4 0.069 13.1 0.4 4.4 4 1 0 4 4 4 0 PAN domain DDE_1 PF03184.19 KFM74438.1 - 4e-50 169.9 0.1 7.2e-50 169.0 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM74438.1 - 1.8e-12 47.1 0.0 1.6e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM74438.1 - 0.00091 18.8 0.0 0.003 17.1 0.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain PI3K_P85_iSH2 PF16454.5 KFM74439.1 - 1.4e-44 151.6 16.9 1.4e-44 151.6 16.9 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 KFM74439.1 - 5.2e-38 129.0 0.0 1.8e-17 63.2 0.0 2.8 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 KFM74439.1 - 4.6e-26 91.5 1.1 4.6e-26 91.5 1.1 2.0 2 0 0 2 2 2 1 RhoGAP domain SAM_2 PF07647.17 KFM74439.1 - 1.5e-06 28.2 0.1 4.6e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM74439.1 - 7.9e-06 26.2 0.6 1.8e-05 25.1 0.2 1.8 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) C1_1 PF00130.22 KFM74439.1 - 0.0011 18.8 9.0 0.0011 18.8 9.0 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KFM74439.1 - 0.17 11.8 6.9 0.58 10.1 6.9 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KFM74439.1 - 0.35 10.5 5.7 1.4 8.5 0.1 2.7 2 0 0 2 2 2 0 PHD-finger zf-C2HC5 PF06221.13 KFM74439.1 - 0.39 10.8 4.5 0.99 9.4 4.5 1.7 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Fib_alpha PF08702.10 KFM74439.1 - 0.84 9.8 9.9 0.21 11.8 5.5 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family SYCE1 PF15233.6 KFM74439.1 - 1.3 9.0 12.7 0.033 14.2 5.3 2.0 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 APG6_N PF17675.1 KFM74439.1 - 1.4 9.5 14.8 7.7 7.1 14.2 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Tup_N PF08581.10 KFM74439.1 - 2.3 8.6 9.4 2.1 8.7 1.5 2.9 2 0 0 2 2 2 0 Tup N-terminal DUF16 PF01519.16 KFM74439.1 - 2.5 8.6 9.1 2.7 8.6 7.1 2.2 2 1 0 2 2 1 0 Protein of unknown function DUF16 Rab_bind PF16704.5 KFM74439.1 - 4 7.5 7.9 11 6.2 1.2 3.8 2 1 2 4 4 4 0 Rab binding domain HALZ PF02183.18 KFM74439.1 - 4.3 7.6 9.1 5 7.4 3.8 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3450 PF11932.8 KFM74439.1 - 5.1 6.3 11.2 0.38 10.0 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Glypican PF01153.19 KFM74440.1 - 7.3e-13 48.2 0.5 8.5e-13 48.0 0.5 1.0 1 0 0 1 1 1 1 Glypican Amidase PF01425.21 KFM74441.1 - 6.6e-74 249.5 0.0 9.4e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KFM74442.1 - 2.8e-75 254.0 0.0 3.7e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 Amidase TIP49_C PF17856.1 KFM74442.1 - 0.32 11.2 1.3 11 6.2 0.0 2.9 3 0 0 3 3 3 0 TIP49 AAA-lid domain Orn_Arg_deC_N PF02784.16 KFM74443.1 - 5.6e-63 212.6 0.0 7.1e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFM74443.1 - 8.1e-23 80.5 0.0 1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 KFM74443.1 - 0.00022 20.9 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain SF3A3 PF16837.5 KFM74444.1 - 0.097 13.2 0.3 0.29 11.7 0.3 1.8 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 HTH_Tnp_Tc3_2 PF01498.18 KFM74445.1 - 3e-16 59.4 2.7 3e-16 59.4 2.7 2.5 3 0 0 3 3 2 1 Transposase DDE_3 PF13358.6 KFM74445.1 - 6.3e-10 39.0 0.0 2.8e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.23 KFM74445.1 - 5.7e-05 23.0 0.7 0.00012 22.0 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle HTH_28 PF13518.6 KFM74445.1 - 9.7e-05 22.4 3.1 0.00012 22.1 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain RVT_1 PF00078.27 KFM74445.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PNMA PF14893.6 KFM74445.1 - 0.0041 16.6 0.2 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 PNMA HTH_23 PF13384.6 KFM74445.1 - 0.015 15.1 0.9 0.14 12.0 0.1 2.6 2 0 0 2 2 2 0 Homeodomain-like domain SKA2 PF16740.5 KFM74445.1 - 0.039 13.7 1.7 6.6 6.6 0.1 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 CENP-B_N PF04218.13 KFM74445.1 - 0.073 12.7 0.0 0.27 10.9 0.0 2.0 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Retrotrans_gag PF03732.17 KFM74445.1 - 0.15 12.4 0.0 0.47 10.8 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein PAM2 PF07145.15 KFM74445.1 - 0.17 11.6 0.4 0.46 10.3 0.4 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region HTH_Tnp_ISL3 PF13542.6 KFM74445.1 - 0.2 11.1 2.3 0.29 10.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Fib_alpha PF08702.10 KFM74445.1 - 0.21 11.8 1.1 2.4 8.3 0.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HTH_32 PF13565.6 KFM74445.1 - 2.4 8.8 13.2 0.069 13.8 2.3 3.4 4 0 0 4 4 3 0 Homeodomain-like domain Prokineticin PF06607.11 KFM74446.1 - 1.8e-06 28.2 3.2 2.2e-06 27.9 3.2 1.1 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM74446.1 - 0.0058 17.2 9.6 0.0098 16.5 9.6 1.4 1 0 0 1 1 1 1 MIT-like atracotoxin family HTH_Tnp_Tc3_2 PF01498.18 KFM74447.1 - 4e-16 59.0 3.5 5.8e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74447.1 - 1.3e-13 51.0 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74447.1 - 2e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74447.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74447.1 - 2.4 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain MIT_LIKE_ACTX PF17556.2 KFM74448.1 - 0.01 16.4 9.4 0.021 15.4 9.4 1.5 1 0 0 1 1 1 0 MIT-like atracotoxin family Prokineticin PF06607.11 KFM74448.1 - 0.015 15.6 1.6 0.024 15.0 1.6 1.4 1 0 0 1 1 1 0 Prokineticin Colipase_C PF02740.14 KFM74448.1 - 0.021 15.0 2.4 0.032 14.4 1.7 1.8 1 1 0 1 1 1 0 Colipase, C-terminal domain Nodulin_late PF07127.11 KFM74448.1 - 0.035 14.5 0.1 0.035 14.5 0.1 2.5 3 1 0 3 3 3 0 Late nodulin protein Dickkopf_N PF04706.12 KFM74448.1 - 8.9 6.9 14.6 4.8 7.8 4.1 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Prokineticin PF06607.11 KFM74449.1 - 4.5e-05 23.7 1.7 5.9e-05 23.3 1.7 1.2 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFM74449.1 - 0.0024 18.4 6.3 0.0063 17.1 6.3 1.8 1 1 0 1 1 1 1 MIT-like atracotoxin family Nodulin_late PF07127.11 KFM74449.1 - 0.026 14.8 1.4 0.026 14.8 1.4 2.2 2 0 0 2 2 2 0 Late nodulin protein Metallothio_6 PF05522.11 KFM74449.1 - 0.72 10.4 10.9 1.6 9.3 3.2 2.2 1 1 1 2 2 2 0 Metallothionein HTH_48 PF17906.1 KFM74450.1 - 0.00071 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Rnk_N PF14760.6 KFM74450.1 - 1 9.9 9.5 0.23 11.9 4.1 2.4 3 0 0 3 3 3 0 Rnk N-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM74451.1 - 3.8e-09 36.7 3.0 3.8e-09 36.7 3.0 2.3 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM74451.1 - 2e-06 27.6 0.1 1e-05 25.3 0.1 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74451.1 - 0.05 13.4 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Nterm_IS4 PF13006.7 KFM74451.1 - 0.078 13.2 0.2 0.36 11.0 0.0 2.2 2 1 0 2 2 2 0 Insertion element 4 transposase N-terminal PH PF00169.29 KFM74452.1 - 6.2e-10 39.5 0.2 1.8e-09 38.0 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM74452.1 - 1.3e-05 25.6 2.6 6.3e-05 23.4 2.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFM74452.1 - 0.0021 18.3 1.2 0.027 14.8 0.4 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain zf-H2C2_2 PF13465.6 KFM74453.1 - 1.7e-52 173.6 79.4 1.8e-07 31.3 2.6 10.8 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74453.1 - 6.2e-39 130.3 96.3 1.9e-05 24.8 0.7 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-met PF12874.7 KFM74453.1 - 2.2e-26 91.4 74.1 0.0041 17.5 3.4 10.3 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM74453.1 - 4.7e-25 86.1 88.5 0.00056 20.5 0.5 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74453.1 - 8.2e-18 64.2 60.2 0.013 15.8 0.5 10.3 10 0 0 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM74453.1 - 1.7e-07 31.1 70.8 0.00079 19.4 0.4 9.8 10 0 0 10 10 10 6 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM74453.1 - 0.00047 20.1 42.8 1.5 8.9 2.0 9.4 5 3 5 10 10 10 3 Sec23/Sec24 zinc finger BolA PF01722.18 KFM74453.1 - 0.00062 20.0 14.4 8 6.8 0.0 6.0 1 1 6 7 7 7 3 BolA-like protein zf_UBZ PF18439.1 KFM74453.1 - 0.0096 15.5 45.8 0.61 9.7 0.3 9.8 9 1 1 10 10 10 4 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFM74453.1 - 0.019 14.7 0.1 0.019 14.7 0.1 9.7 9 1 1 10 10 10 0 zinc-finger C2H2-type DUF4428 PF14471.6 KFM74453.1 - 0.02 14.8 36.3 0.83 9.6 1.6 6.7 5 2 1 6 6 6 0 Domain of unknown function (DUF4428) zf-H2C2_5 PF13909.6 KFM74453.1 - 0.025 14.3 0.4 0.025 14.3 0.4 9.7 9 1 0 9 9 9 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 KFM74453.1 - 0.23 11.6 39.8 0.69 10.1 0.5 7.1 5 2 0 6 6 6 0 Zinc ribbon domain DUF3268 PF11672.8 KFM74453.1 - 0.26 11.6 28.3 2 8.8 1.7 5.0 4 1 0 5 5 5 0 zinc-finger-containing domain zf-C2HC_2 PF13913.6 KFM74453.1 - 0.34 10.9 47.2 0.7 9.9 0.1 9.9 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM74453.1 - 0.48 10.3 26.2 6.3 6.7 0.2 7.3 5 2 3 8 8 8 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM74453.1 - 1.2 10.0 39.9 2.3 9.0 3.2 5.4 1 1 5 6 6 6 0 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM74453.1 - 3.1 7.9 41.3 3.2 7.9 1.2 4.8 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type EGF PF00008.27 KFM74454.1 - 1.4e-27 95.6 69.7 1.2e-07 31.9 8.8 5.5 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 KFM74454.1 - 2.7e-13 50.0 51.7 7.9e-05 23.1 5.9 5.8 5 0 0 5 5 5 5 Human growth factor-like EGF Cadherin PF00028.17 KFM74454.1 - 1.8e-10 41.1 0.0 7.5e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Cadherin domain GPS PF01825.21 KFM74454.1 - 2.1e-10 40.9 0.1 2.1e-10 40.9 0.1 4.2 6 0 0 6 6 6 1 GPCR proteolysis site, GPS, motif EGF_2 PF07974.13 KFM74454.1 - 9.7e-09 35.5 75.0 0.0091 16.3 8.8 5.6 5 0 0 5 5 5 5 EGF-like domain fn3 PF00041.21 KFM74454.1 - 7.2e-08 32.7 0.5 2e-07 31.3 0.5 1.8 1 0 0 1 1 1 1 Fibronectin type III domain EGF_CA PF07645.15 KFM74454.1 - 0.00042 20.5 9.8 0.00042 20.5 9.8 5.7 2 1 3 5 5 5 1 Calcium-binding EGF domain 7tm_2 PF00002.24 KFM74455.1 - 7.1e-30 104.1 12.0 1e-29 103.5 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) CactinC_cactus PF09732.9 KFM74456.1 - 9e-57 190.4 9.8 1.5e-56 189.7 9.8 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 KFM74457.1 - 2.1e-49 167.9 9.2 2.1e-49 167.9 9.2 1.6 2 1 0 2 2 2 1 Conserved mid region of cactin TMEM247 PF15444.6 KFM74457.1 - 4.7 7.2 10.1 12 5.9 10.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 TSSC4 PF15264.6 KFM74458.1 - 2.9e-11 43.7 0.9 4.2e-10 40.0 0.9 2.3 1 1 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 Tnp_P_element PF12017.8 KFM74459.1 - 0.0038 16.7 0.4 0.0059 16.1 0.4 1.3 1 0 0 1 1 1 1 Transposase protein BAR PF03114.18 KFM74461.1 - 1.6e-27 96.7 5.4 1.9e-27 96.4 5.4 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 KFM74461.1 - 0.0014 18.3 1.7 0.0014 18.3 1.7 1.5 1 1 0 1 1 1 1 Arfaptin-like domain Aminopep PF10023.9 KFM74461.1 - 0.0026 17.2 3.3 0.0033 16.8 3.3 1.2 1 0 0 1 1 1 1 Putative aminopeptidase DUF1664 PF07889.12 KFM74461.1 - 0.035 14.1 2.4 3.7 7.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CX9C PF16860.5 KFM74461.1 - 0.047 13.7 1.7 0.23 11.5 0.2 2.5 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ACP_PD PF04336.12 KFM74461.1 - 0.11 12.9 1.4 0.35 11.3 0.1 2.1 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase HTH_Tnp_Tc3_2 PF01498.18 KFM74462.1 - 1.5e-14 53.9 0.7 3.2e-14 52.9 0.7 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74462.1 - 1.9e-14 53.7 0.0 3.4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM74462.1 - 9.5e-06 26.1 8.3 1.6e-05 25.4 1.5 3.1 3 0 0 3 3 3 1 Homeodomain-like domain NCD2 PF04905.13 KFM74463.1 - 5.2e-60 200.9 0.0 1.2e-59 199.8 0.0 1.6 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) NCD1 PF04904.13 KFM74463.1 - 4.7e-44 148.3 0.1 9e-44 147.4 0.1 1.5 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) tRNA-synt_1b PF00579.25 KFM74463.1 - 0.13 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) SKA2 PF16740.5 KFM74463.1 - 1 9.2 6.7 4.8 7.0 0.9 2.9 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 KFM74463.1 - 1.1 9.1 5.5 5.8 6.8 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator Prefoldin_2 PF01920.20 KFM74463.1 - 1.5 8.9 7.7 2.5 8.1 1.2 2.6 1 1 1 2 2 2 0 Prefoldin subunit Collagen PF01391.18 KFM74465.1 - 2.2e-40 136.2 155.1 1.6e-10 40.5 30.7 5.8 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWC PF00093.18 KFM74465.1 - 1.9e-11 44.1 15.6 2.7e-11 43.6 15.6 1.2 1 0 0 1 1 1 1 von Willebrand factor type C domain TILa PF12714.7 KFM74465.1 - 0.00016 21.6 7.4 0.00027 20.8 7.4 1.4 1 0 0 1 1 1 1 TILa domain CFC PF09443.10 KFM74465.1 - 0.064 13.1 1.5 0.12 12.2 1.5 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Amnionless PF14828.6 KFM74465.1 - 7.4 5.3 13.3 10 4.8 13.3 1.1 1 0 0 1 1 1 0 Amnionless Collagen PF01391.18 KFM74466.1 - 3.2e-116 379.1 451.6 2.4e-10 40.0 33.5 13.7 1 1 11 12 12 12 10 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFM74466.1 - 6.5e-79 264.5 1.5 7.9e-79 264.2 1.5 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain C2 PF00168.30 KFM74467.1 - 0.00042 20.6 0.0 0.00093 19.5 0.0 1.5 1 1 0 1 1 1 1 C2 domain CH PF00307.31 KFM74467.1 - 0.11 12.7 0.4 0.92 9.7 0.1 2.1 1 1 1 2 2 2 0 Calponin homology (CH) domain KIF1B PF12423.8 KFM74468.1 - 1.3e-07 31.9 1.6 2.9e-07 30.8 1.6 1.6 1 0 0 1 1 1 1 Kinesin protein 1B Activator-TraM PF11657.8 KFM74468.1 - 0.082 12.8 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Transcriptional activator TraM DCA16 PF15349.6 KFM74468.1 - 0.23 11.0 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Kinesin PF00225.23 KFM74469.1 - 2.8e-21 75.8 0.3 5.4e-21 74.9 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 KFM74469.1 - 5.4e-06 26.7 2.8 1.1e-05 25.7 2.8 1.5 1 1 0 1 1 1 1 Kinesin-associated DDE_Tnp_2 PF04693.12 KFM74469.1 - 0.0096 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal putative transposase ISC1217 Wtap PF17098.5 KFM74469.1 - 0.031 14.2 5.2 0.059 13.3 4.6 1.6 1 1 0 1 1 1 0 WTAP/Mum2p family eIF-4B PF06273.11 KFM74469.1 - 0.032 13.3 4.5 0.036 13.1 4.5 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Microtub_bind PF13931.6 KFM74469.1 - 0.046 14.1 1.4 0.071 13.5 1.4 1.3 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding GAS PF13851.6 KFM74469.1 - 0.55 9.6 13.5 2.1 7.6 0.4 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 KFM74469.1 - 0.56 10.3 7.0 3.2 7.9 1.3 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 HTH_Tnp_Tc3_2 PF01498.18 KFM74470.1 - 1.3e-17 63.8 1.8 6.4e-16 58.4 2.2 2.7 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM74470.1 - 1.5e-13 50.7 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74470.1 - 1.8e-06 27.6 1.8 4e-06 26.5 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74470.1 - 0.0093 15.7 0.5 0.029 14.2 0.5 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74470.1 - 0.86 10.3 14.6 0.14 12.8 1.9 3.4 3 1 1 4 4 4 0 Homeodomain-like domain RabGAP-TBC PF00566.18 KFM74472.1 - 1.9e-41 142.1 0.1 2.2e-40 138.6 0.0 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 KFM74472.1 - 0.00081 19.8 3.6 0.027 14.9 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM74472.1 - 0.0012 18.6 0.3 0.011 15.7 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFM74472.1 - 0.0058 16.1 1.9 0.0095 15.4 0.2 2.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFM74472.1 - 0.046 13.6 0.2 0.15 11.9 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KFM74472.1 - 0.067 12.7 0.7 0.23 11.0 0.7 2.0 1 0 0 1 1 1 0 EF hand Arg_repressor PF01316.21 KFM74474.1 - 0.086 12.6 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain GRAM PF02893.20 KFM74475.1 - 3.6e-15 55.8 0.2 5.5e-15 55.2 0.2 1.3 1 0 0 1 1 1 1 GRAM domain LRR_8 PF13855.6 KFM74476.1 - 1.4e-34 117.6 23.7 1.2e-11 44.2 2.9 7.6 4 1 2 7 7 7 6 Leucine rich repeat TIR PF01582.20 KFM74476.1 - 1.1e-19 70.9 0.2 1.3e-18 67.4 0.0 2.1 2 0 0 2 2 2 1 TIR domain LRR_5 PF13306.6 KFM74476.1 - 2.4e-16 59.9 13.6 5.5e-08 32.8 0.2 4.2 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM74476.1 - 9.9e-16 57.6 27.5 0.0034 17.8 0.0 8.1 3 1 8 11 11 11 8 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 KFM74476.1 - 5e-14 52.9 0.1 1.6e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.6 KFM74476.1 - 0.022 14.3 8.9 0.32 10.5 0.4 3.4 3 1 1 4 4 4 0 Leucine-rich repeat DUF1863 PF08937.11 KFM74476.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.8 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) LRR_1 PF00560.33 KFM74476.1 - 2.5 9.0 26.1 85 4.3 0.0 9.3 11 0 0 11 11 11 0 Leucine Rich Repeat PAP2 PF01569.21 KFM74477.1 - 1e-24 86.8 2.3 1.9e-24 86.0 2.3 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFM74477.1 - 0.001 19.6 3.5 0.0033 17.9 3.5 1.9 1 0 0 1 1 1 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 KFM74477.1 - 0.022 14.4 0.5 0.022 14.4 0.5 1.7 2 0 0 2 2 2 0 PAP2 superfamily MNHE PF01899.16 KFM74477.1 - 0.04 13.7 2.0 2.1 8.1 0.2 2.3 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit LrgB PF04172.16 KFM74477.1 - 0.084 12.4 0.7 0.15 11.5 0.4 1.6 2 0 0 2 2 2 0 LrgB-like family DUF1516 PF07457.11 KFM74477.1 - 0.092 13.0 1.7 0.59 10.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1516) DDE_3 PF13358.6 KFM74479.1 - 1.3e-09 37.9 0.0 1.8e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PPO1_DWL PF12142.8 KFM74479.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Polyphenol oxidase middle domain AATF-Che1 PF13339.6 KFM74481.1 - 3.2e-28 99.2 11.8 3.2e-28 99.2 11.8 3.9 3 3 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 KFM74481.1 - 1.4e-24 86.4 0.9 1.4e-24 86.4 0.9 2.7 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal DUF4570 PF15134.6 KFM74481.1 - 0.056 13.5 5.7 0.2 11.7 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Gpi1 PF05024.15 KFM74484.1 - 2.4e-14 53.8 2.8 2.4e-14 53.8 2.8 1.9 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ig_3 PF13927.6 KFM74486.1 - 2.8e-23 82.3 0.1 6.4e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM74486.1 - 1.9e-21 75.9 0.0 9.8e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM74486.1 - 1e-17 64.2 0.0 2.4e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM74486.1 - 4.1e-16 58.9 0.0 1.6e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM74486.1 - 4.2e-08 33.1 0.0 0.00039 20.4 0.0 2.4 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM74486.1 - 8.7e-07 29.3 0.0 0.00089 19.6 0.0 2.7 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM74486.1 - 3.9e-06 27.0 0.1 0.0012 19.1 0.1 2.8 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 KFM74486.1 - 0.00034 20.8 1.8 0.69 10.1 0.0 3.9 2 2 1 3 3 3 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM74486.1 - 0.00061 19.3 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain CBF_beta PF02312.17 KFM74487.1 - 1.5e-24 86.5 0.7 1.8e-24 86.3 0.7 1.1 1 0 0 1 1 1 1 Core binding factor beta subunit MIP PF00230.20 KFM74489.1 - 4.8e-47 160.6 10.0 5.9e-47 160.3 10.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein hEGF PF12661.7 KFM74491.1 - 2.7e-05 24.6 7.6 2.7e-05 24.6 7.6 2.4 2 1 1 3 3 3 1 Human growth factor-like EGF EGF_2 PF07974.13 KFM74491.1 - 0.0017 18.7 9.2 0.0036 17.7 9.3 1.6 1 1 0 1 1 1 1 EGF-like domain EGF PF00008.27 KFM74491.1 - 0.013 15.8 13.6 0.036 14.4 13.6 1.9 1 1 0 1 1 1 0 EGF-like domain EB PF01683.18 KFM74491.1 - 0.021 15.1 8.7 0.034 14.5 8.8 1.3 1 1 0 1 1 1 0 EB module cEGF PF12662.7 KFM74491.1 - 7.7 6.5 13.5 1.4 8.9 1.6 2.5 2 1 0 2 2 2 0 Complement Clr-like EGF-like Laminin_EGF PF00053.24 KFM74492.1 - 7.7e-09 35.6 44.3 0.00048 20.2 12.8 4.2 2 1 2 4 4 4 3 Laminin EGF domain DSL PF01414.19 KFM74492.1 - 7.1e-05 23.0 12.8 7.1e-05 23.0 12.8 3.2 3 0 0 3 3 3 2 Delta serrate ligand EGF_2 PF07974.13 KFM74492.1 - 0.0062 16.9 62.1 1.1 9.7 9.1 6.6 3 3 2 5 5 5 3 EGF-like domain FBA PF04300.13 KFM74494.1 - 5.8e-08 32.6 0.1 6e-08 32.6 0.1 1.0 1 0 0 1 1 1 1 F-box associated region FBA PF04300.13 KFM74495.1 - 1.3e-17 64.1 0.0 2.6e-17 63.1 0.0 1.5 2 0 0 2 2 2 1 F-box associated region F-box-like PF12937.7 KFM74495.1 - 8.3e-11 41.6 0.2 1.4e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM74495.1 - 2.2e-10 40.1 0.7 4.1e-10 39.3 0.7 1.4 1 0 0 1 1 1 1 F-box domain Ribonuc_red_lgC PF02867.15 KFM74496.1 - 2.2e-191 637.0 0.1 3.1e-191 636.5 0.1 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KFM74496.1 - 2.7e-24 85.0 0.0 7.6e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KFM74496.1 - 7.3e-11 42.5 0.2 4.7e-10 39.9 0.0 2.6 3 0 0 3 3 3 1 ATP cone domain DUF1126 PF06565.12 KFM74498.1 - 4.2e-50 167.9 8.7 1.6e-21 76.1 0.0 5.1 4 1 0 4 4 4 3 DUF1126 PH-like domain NUDIX_2 PF13869.6 KFM74498.1 - 0.026 14.1 0.1 0.057 13.0 0.1 1.5 1 0 0 1 1 1 0 Nucleotide hydrolase THAP PF05485.12 KFM74499.1 - 6.9e-09 36.5 1.8 6.9e-09 36.5 1.8 1.7 2 0 0 2 2 2 1 THAP domain YqaJ PF09588.10 KFM74500.1 - 3.6e-14 53.2 0.0 5.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain zf-C2H2 PF00096.26 KFM74501.1 - 9.4e-32 107.7 79.4 0.00013 22.3 1.3 10.5 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74501.1 - 4.4e-23 80.0 77.2 0.019 15.8 0.3 10.7 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM74501.1 - 1.6e-21 75.7 75.9 0.002 18.5 0.4 11.0 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFM74501.1 - 1.9e-13 50.0 61.3 0.0024 17.8 0.4 9.8 9 0 0 9 9 9 6 C2H2-type zinc finger zf-met PF12874.7 KFM74501.1 - 3.2e-10 40.0 57.4 0.037 14.4 0.6 10.6 10 0 0 10 10 10 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM74501.1 - 1.2e-07 31.8 51.0 0.011 16.0 0.2 10.1 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM74501.1 - 0.0017 18.6 4.2 0.0017 18.6 4.2 5.8 4 2 1 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.6 KFM74501.1 - 0.0043 16.8 1.4 0.0043 16.8 1.4 7.0 6 2 0 6 6 6 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFM74501.1 - 0.0073 16.4 36.7 0.6 10.3 0.7 7.3 6 1 1 7 7 7 3 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 KFM74501.1 - 0.018 15.0 5.3 0.018 15.0 5.3 5.5 5 1 1 6 6 6 0 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM74501.1 - 0.055 14.2 42.3 0.64 10.8 4.4 5.9 4 2 1 5 5 5 0 zinc-ribbon family FYVE PF01363.21 KFM74501.1 - 0.081 13.1 50.6 1 9.6 6.7 6.2 3 1 1 4 4 4 0 FYVE zinc finger DUF5435 PF17503.2 KFM74501.1 - 0.42 10.3 5.4 0.11 12.2 0.7 2.0 1 1 0 2 2 2 0 Family of unknown function (DUF5435) ADK_lid PF05191.14 KFM74501.1 - 7.7 6.6 31.6 1.8 8.6 3.1 5.8 4 2 1 5 5 5 0 Adenylate kinase, active site lid zf-FCS PF06467.14 KFM74501.1 - 8.7 6.4 26.2 3.1 7.8 0.3 6.6 6 1 0 6 6 6 0 MYM-type Zinc finger with FCS sequence motif T-box PF00907.22 KFM74503.1 - 2.9e-75 252.6 0.0 3.7e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 T-box C1_2 PF03107.16 KFM74504.1 - 0.65 10.4 11.7 6.5 7.2 4.8 3.7 1 1 1 2 2 2 0 C1 domain RNase_PH PF01138.21 KFM74506.1 - 8.6e-11 42.5 0.0 1.1e-10 42.1 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFM74507.1 - 7.7e-05 22.6 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1590 PF07629.11 KFM74507.1 - 0.21 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) HTH_Tnp_Tc3_2 PF01498.18 KFM74508.1 - 0.00098 19.3 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Transposase Tantalus PF15386.6 KFM74509.1 - 5.6e-10 39.2 2.4 5.6e-10 39.2 2.4 2.9 3 0 0 3 3 3 1 Drosophila Tantalus-like DnaJ PF00226.31 KFM74510.1 - 3e-22 78.5 0.5 6e-22 77.6 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Integrase_H2C2 PF17921.1 KFM74511.1 - 2.5e-19 69.1 0.1 3.7e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM74511.1 - 2e-05 24.7 0.0 4.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 KFM74511.1 - 0.001 19.2 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.18 KFM74512.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74512.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74512.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74512.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74512.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ELO PF01151.18 KFM74513.1 - 7.7e-22 78.0 12.8 8.4e-22 77.9 12.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Pkinase PF00069.25 KFM74514.1 - 2.1e-68 230.5 0.0 5.6e-68 229.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 KFM74514.1 - 1.3e-41 140.5 0.0 5.9e-20 71.1 0.0 3.0 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KFM74514.1 - 2.1e-35 122.3 0.0 4.1e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM74514.1 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFM74514.1 - 0.034 14.1 0.0 0.14 12.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Annexin PF00191.20 KFM74515.1 - 1.2e-31 108.5 1.6 1.1e-17 63.9 0.1 3.0 3 0 0 3 3 3 3 Annexin DUF5638 PF18688.1 KFM74515.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5638) BTB PF00651.31 KFM74518.1 - 9.6e-16 58.0 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HTH_Tnp_Tc3_2 PF01498.18 KFM74519.1 - 5e-12 45.9 0.1 5e-12 45.9 0.1 2.0 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM74519.1 - 1.7e-11 44.1 0.0 1.2e-10 41.4 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74519.1 - 3.5e-06 26.7 4.4 1.1e-05 25.1 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM74519.1 - 0.00015 22.3 12.1 0.024 15.3 5.0 2.8 1 1 1 2 2 2 2 Homeodomain-like domain HTH_50 PF18024.1 KFM74519.1 - 0.014 15.0 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM74519.1 - 0.029 14.2 3.2 0.03 14.1 0.2 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KFM74519.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Tc3 transposase Helicase_C_4 PF13871.6 KFM74519.1 - 0.12 12.0 0.3 0.22 11.2 0.3 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue HTH_29 PF13551.6 KFM74519.1 - 0.15 12.1 4.5 0.16 12.0 3.1 1.9 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.6 KFM74520.1 - 2.7e-16 59.7 0.1 3e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74520.1 - 1.4e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM74521.1 - 1.7e-16 60.2 2.2 5.3e-16 58.6 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74521.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74521.1 - 3.6e-07 29.8 1.7 9.3e-07 28.5 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74521.1 - 0.0027 17.5 1.1 0.0077 16.0 1.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74521.1 - 4.1 8.1 17.2 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM74522.1 - 1.6e-19 69.9 3.6 4.8e-19 68.4 2.1 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74522.1 - 5.1e-11 42.5 0.1 1.5e-07 31.2 0.0 3.2 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_7 PF02796.15 KFM74522.1 - 2.5e-07 30.6 0.9 0.00012 22.0 0.0 2.7 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM74522.1 - 2.7e-07 31.1 4.3 3e-07 31.0 2.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM74522.1 - 1.4e-06 28.4 3.1 6.5e-05 23.0 0.2 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74522.1 - 1.5e-06 27.8 3.5 2.2e-05 24.1 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM74522.1 - 2.4e-06 27.5 0.7 3.4e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM74522.1 - 0.00011 22.1 0.7 0.0014 18.5 0.0 2.5 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM74522.1 - 0.00084 19.3 0.3 0.014 15.3 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM74522.1 - 0.016 14.9 0.1 0.094 12.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM74522.1 - 0.035 14.2 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM74522.1 - 0.075 13.2 0.1 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM74522.1 - 0.13 11.8 0.2 0.71 9.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM74522.1 - 0.14 12.3 0.0 26 5.0 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM74522.1 - 0.14 11.9 3.9 1.3 8.9 0.0 3.3 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM74522.1 - 0.8 9.2 3.6 6.2 6.3 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DDE_Tnp_1_7 PF13843.6 KFM74523.1 - 3.8e-77 260.0 0.0 5.7e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 Nbl1_Borealin_N PF10444.9 KFM74523.1 - 0.61 9.8 5.3 4.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal SASP PF00269.20 KFM74525.1 - 0.014 15.4 1.1 0.021 14.8 1.1 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type Mto2_bdg PF12808.7 KFM74525.1 - 0.11 12.8 3.7 0.16 12.3 3.7 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Transposase_1 PF01359.18 KFM74526.1 - 2.1e-16 59.5 0.4 4.2e-16 58.5 0.1 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM74526.1 - 3.6e-06 27.0 0.1 1.3e-05 25.2 0.1 1.9 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM74526.1 - 0.00026 21.5 0.0 0.00061 20.3 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM74526.1 - 0.0021 18.3 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Transposase Pkinase PF00069.25 KFM74527.1 - 0.0038 16.6 0.0 0.0041 16.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DDE_3 PF13358.6 KFM74528.1 - 8.9e-09 35.3 0.0 9.8e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease BNR PF02012.20 KFM74529.1 - 0.00021 20.8 10.4 0.17 12.0 0.1 5.0 4 0 0 4 4 4 2 BNR/Asp-box repeat EGF_2 PF07974.13 KFM74529.1 - 0.0085 16.4 9.9 0.019 15.3 9.9 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 KFM74529.1 - 0.13 12.4 4.2 0.44 10.6 4.2 1.9 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 KFM74529.1 - 0.22 12.2 5.6 0.76 10.5 5.6 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 KFM74530.1 - 2.5e-08 34.1 38.3 7.2e-05 23.1 15.4 2.9 2 0 0 2 2 2 2 EGF-like domain BNR PF02012.20 KFM74530.1 - 1.7e-05 24.1 9.7 0.77 10.0 0.4 5.1 4 0 0 4 4 4 2 BNR/Asp-box repeat hEGF PF12661.7 KFM74530.1 - 0.0003 21.3 19.9 0.028 15.0 6.1 2.9 2 0 0 2 2 2 2 Human growth factor-like EGF CHB_HEX_C PF03174.13 KFM74530.1 - 0.00067 19.6 0.0 9.2 6.3 0.0 4.1 4 0 0 4 4 4 1 Chitobiase/beta-hexosaminidase C-terminal domain EB PF01683.18 KFM74530.1 - 0.0017 18.6 11.2 0.036 14.4 2.0 2.9 2 0 0 2 2 2 2 EB module Sortilin-Vps10 PF15902.5 KFM74530.1 - 0.0054 15.6 0.4 28 3.3 0.0 3.9 4 0 0 4 4 4 0 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 KFM74530.1 - 0.011 15.1 0.0 3.9 6.7 0.0 3.2 4 0 0 4 4 4 0 BNR repeat-like domain I-EGF_1 PF18372.1 KFM74530.1 - 0.018 15.1 7.3 0.018 15.1 7.3 3.3 3 0 0 3 3 3 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 KFM74530.1 - 0.051 13.9 26.6 0.85 10.0 10.9 2.8 2 0 0 2 2 2 0 EGF-like domain EGF_Tenascin PF18720.1 KFM74530.1 - 0.78 9.9 29.6 0.025 14.6 8.6 3.1 3 0 0 3 3 3 0 Tenascin EGF domain Laminin_EGF PF00053.24 KFM74530.1 - 0.8 9.9 26.2 4.6 7.5 9.4 2.8 2 0 0 2 2 2 0 Laminin EGF domain EGF_Tenascin PF18720.1 KFM74531.1 - 1.5e-05 24.9 5.4 3.2e-05 23.9 5.4 1.6 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 KFM74531.1 - 2.9e-05 24.3 10.9 7.9e-05 22.9 10.9 1.8 1 0 0 1 1 1 1 EGF-like domain I-EGF_1 PF18372.1 KFM74531.1 - 0.056 13.6 7.1 0.15 12.1 7.1 1.8 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 BNR PF02012.20 KFM74531.1 - 0.11 12.6 0.3 0.43 10.8 0.3 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat EGF PF00008.27 KFM74531.1 - 0.14 12.5 7.5 0.32 11.3 7.5 1.7 1 0 0 1 1 1 0 EGF-like domain EB PF01683.18 KFM74531.1 - 1.5 9.1 9.9 0.57 10.5 5.5 2.6 2 1 0 2 2 2 0 EB module HTH_Tnp_Tc3_2 PF01498.18 KFM74532.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74532.1 - 5.9e-13 48.8 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74532.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74532.1 - 0.0025 17.6 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74532.1 - 2.1 9.0 15.6 0.12 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 KFM74534.1 - 3.1e-76 248.7 100.7 1.7e-08 34.5 1.0 14.6 15 0 0 15 15 15 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74534.1 - 8.5e-60 196.0 108.9 6.8e-06 26.2 1.9 13.4 14 0 0 14 14 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74534.1 - 1.4e-43 143.7 94.1 0.00021 21.9 1.6 13.2 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM74534.1 - 4e-28 96.9 87.3 0.00052 20.3 1.0 13.2 13 0 0 13 13 13 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74534.1 - 7.2e-20 70.5 84.0 0.044 13.8 2.1 13.3 13 0 0 13 13 13 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74534.1 - 9.7e-15 54.4 74.1 0.023 15.0 1.4 12.7 13 0 0 13 13 13 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM74534.1 - 7.6e-14 51.8 24.6 0.016 15.5 1.0 9.0 1 1 8 10 10 10 5 BolA-like protein GAGA PF09237.11 KFM74534.1 - 3.3e-08 33.2 34.7 0.024 14.4 0.2 9.4 3 3 9 12 12 12 4 GAGA factor zf-H2C2_5 PF13909.6 KFM74534.1 - 2.3e-07 30.4 71.9 0.065 13.0 0.1 13.4 13 1 1 14 14 14 5 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM74534.1 - 1.1e-06 28.6 50.4 0.031 14.3 0.1 11.5 8 3 4 12 12 12 2 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM74534.1 - 1.9e-05 24.1 66.7 0.25 11.0 0.6 11.6 3 2 9 12 12 12 7 MYST family zinc finger domain zf-C2H2_9 PF16293.5 KFM74534.1 - 0.00032 20.5 44.0 0.34 10.8 0.1 11.4 5 3 7 12 12 12 2 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM74534.1 - 0.0034 17.5 54.2 0.21 11.7 3.5 5.1 1 1 4 5 5 5 3 Putative ribonucleoprotein zinc-finger pf C4 type DUF952 PF06108.12 KFM74534.1 - 0.0076 16.2 6.7 5.7 7.0 0.0 5.5 1 1 4 5 5 5 1 Protein of unknown function (DUF952) zinc_ribbon_15 PF17032.5 KFM74534.1 - 0.078 13.7 53.2 0.83 10.4 1.5 6.7 1 1 5 8 8 8 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM74534.1 - 0.23 11.6 55.9 4.6 7.4 0.9 8.8 4 4 6 10 10 10 0 Zinc ribbon domain zf_UBZ PF18439.1 KFM74534.1 - 0.29 10.7 62.5 1.3 8.7 0.2 12.3 13 0 0 13 13 13 0 Ubiquitin-Binding Zinc Finger Ndufs5 PF10200.9 KFM74534.1 - 0.32 11.3 19.2 0.28 11.5 0.5 4.6 2 2 3 5 5 5 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa ADK_lid PF05191.14 KFM74534.1 - 1.8 8.6 43.5 0.12 12.4 1.1 6.9 4 2 1 5 5 5 0 Adenylate kinase, active site lid DUF2039 PF10217.9 KFM74534.1 - 2.1 8.8 51.2 0.43 10.9 2.6 6.2 1 1 5 6 6 6 0 Uncharacterized conserved protein (DUF2039) zf_ZIC PF18366.1 KFM74534.1 - 2.1 8.5 28.9 8.9 6.5 0.1 8.6 5 4 4 9 9 9 0 Zic proteins zinc finger domain PI3_PI4_kinase PF00454.27 KFM74535.1 - 6.1e-58 196.6 0.0 7.2e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Toxin_16 PF07945.11 KFM74535.1 - 0.062 13.2 5.2 0.11 12.4 5.2 1.3 1 0 0 1 1 1 0 Janus-atracotoxin RNase_H PF00075.24 KFM74537.1 - 0.00057 20.1 0.1 0.0016 18.7 0.0 1.7 2 0 0 2 2 2 1 RNase H Glyco_hydro_97 PF10566.9 KFM74537.1 - 0.074 12.3 0.2 0.082 12.2 0.2 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 zf-H2C2_2 PF13465.6 KFM74539.1 - 1.2e-15 57.1 25.6 5.9e-07 29.6 3.6 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74539.1 - 5.3e-14 51.8 32.3 4.1e-06 27.0 4.3 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74539.1 - 6e-10 39.1 26.1 0.0004 21.0 2.0 3.6 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM74539.1 - 4.9e-09 36.3 16.7 0.0016 18.7 0.3 3.8 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM74539.1 - 2.9e-08 33.8 12.1 0.00046 20.4 0.5 3.8 4 0 0 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KFM74539.1 - 4.9e-06 26.3 11.2 0.016 15.1 0.3 3.4 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 KFM74539.1 - 0.00021 21.6 8.7 0.41 11.0 0.2 3.2 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFM74539.1 - 0.0075 16.7 11.3 2.9 8.4 1.0 3.3 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFM74539.1 - 0.0095 15.9 0.9 0.0095 15.9 0.9 3.9 5 0 0 5 5 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFM74539.1 - 0.014 15.5 6.7 5.7 7.2 0.2 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFM74539.1 - 0.016 15.0 15.2 0.067 13.0 1.3 3.6 3 1 0 3 3 3 0 zinc-finger C2H2-type GATA PF00320.27 KFM74539.1 - 0.028 14.0 5.7 0.39 10.3 0.1 3.2 2 1 0 2 2 2 0 GATA zinc finger HypA PF01155.19 KFM74539.1 - 0.039 14.0 2.1 0.16 12.0 2.1 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Actin_micro PF17003.5 KFM74539.1 - 0.058 12.6 5.3 1.7 7.7 0.0 2.7 1 1 1 2 2 2 0 Putative actin-like family zinc_ribbon_15 PF17032.5 KFM74539.1 - 0.12 13.1 4.2 0.81 10.5 4.3 2.0 1 1 0 1 1 1 0 zinc-ribbon family HalOD2 PF18547.1 KFM74539.1 - 0.13 12.2 4.3 5.4 7.0 0.3 3.6 3 1 0 3 3 3 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 KFM74539.1 - 0.27 11.2 10.9 3.7 7.5 0.3 3.7 3 1 0 3 3 3 0 SprT-like zinc ribbon domain DZR PF12773.7 KFM74539.1 - 0.33 11.0 4.6 1.3 9.2 4.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_recom PF13408.6 KFM74539.1 - 0.35 11.4 10.9 0.96 10.0 7.7 2.5 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain LIM PF00412.22 KFM74539.1 - 0.36 11.1 8.0 20 5.5 3.6 3.1 2 1 0 2 2 2 0 LIM domain zf-UBR PF02207.20 KFM74539.1 - 0.45 10.7 9.7 2.2 8.5 4.0 2.2 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF629 PF04780.12 KFM74539.1 - 0.46 8.9 8.5 0.95 7.9 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf_UBZ PF18439.1 KFM74539.1 - 0.66 9.6 5.6 2.7 7.7 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KFM74539.1 - 1.1 9.5 11.6 7.3 7.0 3.5 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon TFIIS_C PF01096.18 KFM74539.1 - 1.3 8.9 7.1 7.4 6.5 0.2 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-Mss51 PF13824.6 KFM74539.1 - 2.2 8.4 6.8 5 7.3 1.8 2.5 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-AN1 PF01428.16 KFM74539.1 - 3.6 7.8 14.7 6 7.1 0.4 3.3 2 1 1 3 3 3 0 AN1-like Zinc finger zf-trcl PF13451.6 KFM74539.1 - 5 7.1 9.8 24 4.9 3.9 3.0 2 1 0 2 2 2 0 Probable zinc-ribbon domain PH_9 PF15410.6 KFM74540.1 - 3e-48 163.1 2.6 6.3e-48 162.1 0.2 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain Sec7 PF01369.20 KFM74540.1 - 5.9e-39 133.6 0.3 2e-38 131.9 0.2 2.0 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 KFM74540.1 - 3.5e-09 37.1 0.6 8e-09 36.0 0.1 1.9 2 0 0 2 2 2 1 PH domain PH_2 PF08458.10 KFM74540.1 - 0.0084 16.4 0.1 0.036 14.4 0.0 2.1 2 0 0 2 2 2 1 Plant pleckstrin homology-like region DUF695 PF05117.12 KFM74540.1 - 0.0099 16.1 0.2 0.57 10.4 0.0 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF695) DUF2655 PF10848.8 KFM74540.1 - 0.16 12.3 0.0 0.5 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) HTH_Tnp_Tc3_2 PF01498.18 KFM74541.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74541.1 - 9.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_3 PF00003.22 KFM74543.1 - 0.00012 21.9 0.5 0.00013 21.8 0.5 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR 7tm_3 PF00003.22 KFM74544.1 - 1.1e-17 64.6 2.3 1.1e-17 64.6 2.3 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Arena_RNA_pol PF06317.11 KFM74544.1 - 0.2 8.8 0.5 0.22 8.7 0.5 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase IBR PF01485.21 KFM74547.1 - 0.0049 17.1 3.3 0.0097 16.1 3.3 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain FAD_binding_1 PF00667.20 KFM74548.1 - 7.1e-36 123.9 0.0 1.9e-35 122.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 KFM74548.1 - 1.9e-27 96.2 0.0 3.9e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFM74548.1 - 2.1e-18 67.0 0.0 6.6e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SIS_2 PF13580.6 KFM74548.1 - 0.0029 17.6 0.2 0.054 13.5 0.2 2.7 3 0 0 3 3 3 1 SIS domain PGM_PMM_I PF02878.16 KFM74548.1 - 0.0056 16.4 0.1 0.025 14.3 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF915 PF06028.11 KFM74548.1 - 0.025 13.9 0.4 0.044 13.1 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) NAD_binding_6 PF08030.12 KFM74548.1 - 0.084 13.0 0.2 0.96 9.6 0.0 2.3 1 1 0 2 2 2 0 Ferric reductase NAD binding domain F-box PF00646.33 KFM74549.1 - 8.7e-10 38.2 0.1 3.6e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFM74549.1 - 2.8e-07 30.3 0.0 1e-05 25.3 0.1 2.3 2 0 0 2 2 2 1 F-box-like HTH_28 PF13518.6 KFM74550.1 - 2.4e-07 30.8 0.2 5.9e-07 29.5 0.0 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM74550.1 - 6.3e-07 29.4 0.5 0.00015 21.8 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM74550.1 - 2.8e-06 26.9 0.4 5e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KFM74550.1 - 0.00032 20.3 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 KFM74550.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KFM74550.1 - 0.0012 18.7 0.1 0.0019 18.1 0.1 1.6 1 1 1 2 2 2 1 MarR family HTH_38 PF13936.6 KFM74550.1 - 0.0016 18.2 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM74550.1 - 0.0027 17.7 0.5 0.0037 17.3 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM74550.1 - 0.0055 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Tc3 transposase HTH_32 PF13565.6 KFM74550.1 - 0.013 16.1 0.5 0.024 15.3 0.5 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_5 PF01022.20 KFM74550.1 - 0.073 12.9 0.4 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.16 KFM74550.1 - 0.078 12.5 0.1 0.078 12.5 0.1 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 DZR PF12773.7 KFM74552.1 - 0.078 13.0 19.5 1.1 9.3 0.4 3.7 3 1 1 4 4 4 0 Double zinc ribbon zf-C2H2 PF00096.26 KFM74552.1 - 0.081 13.4 0.1 0.081 13.4 0.1 4.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type RT_RNaseH_2 PF17919.1 KFM74554.1 - 1e-30 105.7 0.0 4.8e-30 103.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM74554.1 - 2.7e-29 101.5 0.0 1.3e-28 99.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM74554.1 - 2e-28 99.4 0.1 5.6e-28 98.0 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM74554.1 - 2e-18 66.7 0.0 3.6e-17 62.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM74554.1 - 2.1e-16 59.7 0.0 7.7e-16 58.0 0.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain Arc_C PF18162.1 KFM74554.1 - 3.6e-05 23.5 1.7 0.00013 21.7 0.4 2.7 3 0 0 3 3 3 1 Arc C-lobe zf-H2C2 PF09337.10 KFM74554.1 - 0.0015 18.7 0.0 0.004 17.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM74554.1 - 0.021 15.1 2.8 0.23 11.8 0.0 3.7 3 0 0 3 3 3 0 Retrotransposon gag protein HTH_Tnp_Tc3_2 PF01498.18 KFM74555.1 - 2.4e-16 59.7 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74555.1 - 9.9e-14 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4817 PF16087.5 KFM74558.1 - 1e-11 44.4 0.0 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 KFM74558.1 - 0.00043 20.8 2.9 0.00081 20.0 1.5 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM74558.1 - 0.03 14.4 0.7 0.23 11.5 0.2 2.4 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 KFM74558.1 - 0.045 13.9 0.1 2.6 8.2 0.0 3.1 4 0 0 4 4 4 0 Helix-turn-helix domain Trypsin PF00089.26 KFM74559.1 - 1.2e-35 123.3 0.0 1.6e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM74559.1 - 3.4e-05 24.2 0.0 6.2e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFM74559.1 - 0.00015 22.7 0.0 0.00021 22.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Zwilch PF09817.9 KFM74560.1 - 4.3e-25 88.2 2.8 7.7e-25 87.4 2.8 1.3 1 1 0 1 1 1 1 RZZ complex, subunit zwilch Zwilch PF09817.9 KFM74561.1 - 1e-11 44.0 0.0 1.1e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 RZZ complex, subunit zwilch Mito_carr PF00153.27 KFM74563.1 - 1.2e-49 166.1 0.9 1.3e-25 89.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM74563.1 - 0.022 13.9 0.3 0.74 8.9 0.0 2.6 3 1 0 3 3 3 0 Gammaproteobacterial serine protease CRAL_TRIO_2 PF13716.6 KFM74564.1 - 3.3e-34 118.0 0.5 4.7e-34 117.5 0.5 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain BNIP2 PF12496.8 KFM74564.1 - 3.3e-11 43.8 27.2 1.1e-09 38.9 25.7 3.7 2 1 0 2 2 2 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO PF00650.20 KFM74564.1 - 6.3e-07 29.2 0.1 1.1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain THAP PF05485.12 KFM74565.1 - 2.8e-07 31.4 0.1 2.8e-07 31.4 0.1 1.0 1 0 0 1 1 1 1 THAP domain DDE_3 PF13358.6 KFM74567.1 - 2.8e-07 30.4 0.1 3.6e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KFM74569.1 - 1.3e-29 103.1 0.3 2.1e-29 102.4 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM74569.1 - 4.2e-11 42.7 0.2 4.2e-11 42.7 0.2 2.2 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain BrkDBD PF09607.10 KFM74569.1 - 7.1e-09 35.3 0.3 1.9e-08 33.9 0.3 1.7 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_1 PF01527.20 KFM74569.1 - 0.00077 19.7 3.1 0.00077 19.7 3.1 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74569.1 - 0.01 15.6 0.0 0.099 12.4 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease LolA PF03548.15 KFM74569.1 - 0.025 14.3 0.0 0.07 12.8 0.0 1.8 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Homeodomain PF00046.29 KFM74570.1 - 4.2e-23 80.9 2.3 4.2e-23 80.9 2.3 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFM74570.1 - 0.0012 18.7 0.1 0.0028 17.5 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFM74570.1 - 0.036 13.5 0.1 0.074 12.5 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFM74570.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT GerE PF00196.19 KFM74570.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family SET PF00856.28 KFM74571.1 - 1.3e-17 64.7 6.1 1.4e-17 64.6 1.9 2.9 2 1 0 2 2 2 1 SET domain Bromodomain PF00439.25 KFM74571.1 - 9.1e-16 57.7 0.4 2.5e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 Bromodomain AWS PF17907.1 KFM74571.1 - 2.3e-07 30.8 3.3 2.3e-07 30.8 3.3 2.6 3 0 0 3 3 3 1 AWS domain PHD PF00628.29 KFM74571.1 - 1.3e-05 25.0 15.1 1.8e-05 24.5 12.7 2.4 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFM74571.1 - 0.038 13.6 8.1 0.11 12.1 8.1 1.9 1 0 0 1 1 1 0 PHD-finger Colicin_immun PF09204.10 KFM74571.1 - 0.46 11.1 4.1 21 5.7 0.2 3.9 3 1 1 4 4 4 0 Bacterial self-protective colicin-like immunity BAH PF01426.18 KFM74572.1 - 1.9e-18 66.5 0.3 1.9e-18 66.5 0.3 1.7 2 0 0 2 2 2 1 BAH domain Peptidase_C14 PF00656.22 KFM74574.1 - 2.1e-15 57.3 0.2 2.3e-15 57.2 0.2 1.0 1 0 0 1 1 1 1 Caspase domain DUF3510 PF12022.8 KFM74574.1 - 0.079 13.4 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) ssDNA_TraI_N PF18272.1 KFM74574.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain MHC_I_3 PF16497.5 KFM74575.1 - 0.058 12.9 0.1 0.058 12.9 0.1 1.0 1 0 0 1 1 1 0 MHC-I family domain Pyridoxal_deC PF00282.19 KFM74577.1 - 4.9e-131 436.9 0.0 6e-131 436.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFM74577.1 - 0.00067 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFM74577.1 - 0.0017 17.4 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KFM74577.1 - 0.0022 16.8 0.0 0.003 16.3 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain F-box_5 PF18511.1 KFM74577.1 - 0.098 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 F-box SepSecS PF05889.13 KFM74577.1 - 0.14 10.8 0.0 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF2704 PF10866.8 KFM74577.1 - 0.15 11.9 0.7 0.32 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2704) FGGY_C PF02782.16 KFM74579.1 - 4.6e-22 78.7 0.0 6.9e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFM74580.1 - 0.00042 19.9 0.0 0.00044 19.9 0.0 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_N PF00370.21 KFM74582.1 - 0.0016 18.1 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM74584.1 - 1.9e-31 108.1 16.3 1.6e-15 57.1 2.2 2.7 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM74584.1 - 1.4e-30 106.0 0.0 1.9e-14 53.6 0.0 3.2 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74584.1 - 6.8e-08 32.2 4.0 1.7e-06 27.7 0.2 3.9 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74584.1 - 1.2e-07 31.3 2.0 0.018 14.8 0.5 4.0 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 KFM74584.1 - 1.4e-05 25.1 3.1 0.1 12.7 0.1 3.1 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM74584.1 - 0.00012 21.8 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 Tc3 transposase HTH_32 PF13565.6 KFM74584.1 - 0.0018 18.9 1.5 0.0018 18.9 1.5 4.8 4 1 1 5 5 5 2 Homeodomain-like domain HTH_7 PF02796.15 KFM74584.1 - 0.0058 16.7 0.1 0.73 10.0 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM74584.1 - 0.012 15.7 6.3 0.071 13.1 0.2 3.2 3 0 0 3 3 3 0 Winged helix-turn helix eIF-3_zeta PF05091.12 KFM74585.1 - 2.5 7.0 9.6 3 6.7 9.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Melibiase_2 PF16499.5 KFM74586.1 - 7e-71 238.7 0.1 8.4e-71 238.4 0.1 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 KFM74586.1 - 2.6e-15 56.4 0.0 5.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 KFM74586.1 - 1.4e-08 34.7 0.0 5.3e-08 32.8 0.0 2.0 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Pkinase_Tyr PF07714.17 KFM74587.1 - 2.6e-96 321.9 0.0 4.4e-96 321.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM74587.1 - 3.9e-49 167.4 0.1 1.1e-48 165.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 KFM74587.1 - 3.8e-13 49.3 0.0 1.3e-12 47.6 0.0 2.0 1 0 0 1 1 1 1 SH2 domain FCH PF00611.23 KFM74587.1 - 2.6e-07 30.8 2.5 2.8e-07 30.7 0.3 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Fez1 PF06818.15 KFM74587.1 - 0.021 15.3 1.3 0.021 15.3 1.3 2.2 2 0 0 2 2 2 0 Fez1 Ribosomal_L29 PF00831.23 KFM74587.1 - 0.049 13.6 3.1 0.074 13.0 1.0 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein TPR_MLP1_2 PF07926.12 KFM74587.1 - 0.87 9.7 10.4 1.4 9.0 1.4 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ras PF00071.22 KFM74589.1 - 3.5e-12 46.2 0.1 3.8e-12 46.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM74589.1 - 9.4e-12 45.2 0.0 1e-11 45.1 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFM74589.1 - 0.00024 20.5 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial TniB protein Arf PF00025.21 KFM74589.1 - 0.00063 19.2 0.0 0.00063 19.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFM74589.1 - 0.013 15.0 0.0 0.013 15.0 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KFM74589.1 - 0.026 14.1 0.0 0.026 14.1 0.0 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KFM74589.1 - 0.029 14.1 0.1 0.031 14.0 0.1 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KFM74589.1 - 0.054 13.6 0.0 0.054 13.6 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KFM74589.1 - 0.094 12.4 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 KFM74590.1 - 1.4e-83 280.6 0.1 1.7e-83 280.3 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM74590.1 - 4e-32 111.4 0.2 5.6e-32 110.9 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Globin PF00042.22 KFM74592.1 - 8.3e-20 71.4 0.0 1.2e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Globin SH2 PF00017.24 KFM74593.1 - 3e-08 33.7 0.0 4.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 SH2 domain DDE_3 PF13358.6 KFM74594.1 - 3.1e-05 23.8 0.0 5.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1759 PF03564.15 KFM74595.1 - 1.4e-28 99.7 3.9 1.4e-28 99.7 3.9 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM74595.1 - 4.7e-13 49.2 0.0 9.3e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 KFM74595.1 - 0.00033 21.2 0.0 0.0011 19.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM74595.1 - 0.092 13.3 0.0 0.37 11.4 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease PseudoU_synth_2 PF00849.22 KFM74596.1 - 8e-30 104.0 0.1 1.6e-29 103.1 0.1 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KFM74596.1 - 0.0002 21.0 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ub-Mut7C PF14451.6 KFM74596.1 - 0.0023 17.7 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 Mut7-C ubiquitin TGS PF02824.21 KFM74596.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 TGS domain UCH PF00443.29 KFM74598.1 - 1.5e-79 267.1 0.4 2.2e-79 266.6 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 KFM74598.1 - 3.7e-36 123.0 0.1 7.6e-36 122.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUSP PF06337.12 KFM74598.1 - 8.7e-24 84.0 0.3 4.2e-23 81.8 0.3 2.3 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KFM74598.1 - 1.5e-15 57.6 0.3 9.5e-09 35.3 0.2 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KFM74598.1 - 1e-10 41.7 0.1 8.9e-09 35.3 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 KFM74598.1 - 4.2e-05 23.0 0.1 0.0003 20.2 0.0 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 Ubiquitin_2 PF14560.6 KFM74598.1 - 0.022 15.2 1.4 0.22 12.0 0.4 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Pkinase PF00069.25 KFM74602.1 - 3.9e-47 160.8 0.0 5e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM74602.1 - 6.1e-17 61.8 0.0 8.2e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM74602.1 - 0.00032 20.1 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM74602.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFM74602.1 - 0.075 12.6 0.2 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Peptidase_A17 PF05380.13 KFM74603.1 - 4.2e-51 173.2 0.1 1.8e-50 171.1 0.1 2.2 2 0 0 2 2 2 1 Pao retrotransposon peptidase DUF5641 PF18701.1 KFM74603.1 - 1.2e-23 83.1 0.1 3.9e-23 81.4 0.1 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1759 PF03564.15 KFM74603.1 - 1.3e-17 64.1 0.4 5e-17 62.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Exo_endo_phos_2 PF14529.6 KFM74603.1 - 2.3e-15 56.5 0.0 7.1e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1758 PF05585.12 KFM74603.1 - 2.8e-13 50.0 0.2 6.8e-13 48.7 0.2 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 KFM74603.1 - 1.1e-10 41.5 2.7 5.5e-10 39.2 2.7 2.3 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 KFM74603.1 - 1.3e-10 41.1 0.1 1.9e-06 27.6 0.0 2.8 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM74603.1 - 5e-09 36.4 0.0 2.6e-08 34.1 0.0 2.3 1 0 0 1 1 1 1 Integrase core domain Exo_endo_phos PF03372.23 KFM74603.1 - 0.00048 19.7 0.0 0.00095 18.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-H2C2 PF09337.10 KFM74603.1 - 0.0017 18.5 0.9 0.0057 16.8 0.9 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 KFM74603.1 - 0.023 15.3 0.0 0.079 13.6 0.0 1.9 1 1 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 KFM74603.1 - 0.031 14.8 0.0 0.13 12.8 0.0 2.1 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease GF_recep_IV PF14843.6 KFM74603.1 - 1 9.2 13.4 0.2 11.5 8.8 2.1 2 0 0 2 2 2 0 Growth factor receptor domain IV DDE_Tnp_1_7 PF13843.6 KFM74604.1 - 0.00073 18.9 0.7 0.00091 18.6 0.1 1.4 2 0 0 2 2 2 1 Transposase IS4 Ribosomal_L6e PF01159.19 KFM74604.1 - 0.33 11.5 6.2 1.5 9.4 0.2 2.6 1 1 1 2 2 2 0 Ribosomal protein L6e Glycogen_syn PF05693.13 KFM74606.1 - 0 1152.6 0.0 0 1152.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KFM74606.1 - 3.1e-08 33.3 0.0 2.6e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM74606.1 - 7.6e-06 26.4 0.0 0.0016 18.9 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFM74606.1 - 1.3e-05 25.2 0.2 2.5e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KFM74606.1 - 0.00014 22.3 0.0 0.0004 20.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DDE_1 PF03184.19 KFM74607.1 - 2.8e-16 59.7 3.1 3.8e-12 46.2 0.7 2.7 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM74607.1 - 5.8e-13 48.7 0.6 4.6e-12 45.8 0.0 2.8 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain FA_FANCE PF11510.8 KFM74607.1 - 1.8e-07 30.8 0.4 3.7e-07 29.8 0.4 1.4 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE HTH_48 PF17906.1 KFM74607.1 - 0.00019 21.5 4.5 0.00042 20.4 0.2 3.4 3 0 0 3 3 3 1 HTH domain in Mos1 transposase CENP-B_N PF04218.13 KFM74607.1 - 0.0035 16.9 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 KFM74607.1 - 0.0068 16.5 0.0 0.023 14.8 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM74607.1 - 0.022 14.6 0.0 0.59 10.0 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain FKBP_C PF00254.28 KFM74608.1 - 1.2e-50 169.8 0.8 2e-32 111.4 0.0 2.5 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KFM74608.1 - 4.3e-17 61.1 9.4 4.2e-06 26.3 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM74608.1 - 4.5e-13 48.2 5.8 4.1e-05 23.4 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM74608.1 - 1.9e-11 43.2 8.7 5.1e-05 23.2 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM74608.1 - 2.5e-08 34.1 3.0 6.8e-06 26.3 1.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM74608.1 - 3.8e-05 24.0 1.0 0.14 12.8 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM74608.1 - 0.00043 20.5 5.7 0.0077 16.4 2.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFM74608.1 - 0.00058 20.1 2.6 0.091 13.2 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM74608.1 - 0.001 19.6 0.1 0.24 12.1 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM74608.1 - 0.0024 17.8 3.1 1.2 9.4 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM74608.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM74608.1 - 0.064 13.0 11.1 0.54 10.0 0.6 3.5 3 1 1 4 4 4 0 TPR repeat TPR_19 PF14559.6 KFM74608.1 - 0.064 13.8 4.6 0.08 13.5 0.6 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM74608.1 - 0.086 12.9 8.7 0.5 10.5 0.3 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KFM74608.1 - 0.12 13.2 0.0 8 7.6 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat NIPSNAP PF07978.13 KFM74609.1 - 1.7e-29 102.0 1.5 5.2e-23 81.2 0.7 2.2 2 0 0 2 2 2 2 NIPSNAP DUF1911 PF08929.10 KFM74609.1 - 0.064 14.1 0.3 0.11 13.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Dimer_Tnp_hAT PF05699.14 KFM74610.1 - 0.00015 21.5 0.1 0.00015 21.5 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Put_DNA-bind_N PF06971.13 KFM74610.1 - 0.17 11.9 2.4 0.19 11.8 0.1 2.0 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus DDE_3 PF13358.6 KFM74611.1 - 3.2e-06 27.0 0.0 5.1e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease SPT16 PF08644.11 KFM74612.1 - 4.4e-59 199.0 0.2 4.4e-59 199.0 0.2 3.0 2 1 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KFM74612.1 - 7.7e-51 172.1 0.7 7.7e-51 172.1 0.7 3.0 2 1 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KFM74612.1 - 1.5e-29 103.2 0.0 2.6e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KFM74612.1 - 8e-18 64.7 0.0 2.9e-17 62.8 0.0 2.1 1 0 0 1 1 1 1 Histone chaperone Rttp106-like LSM PF01423.22 KFM74614.1 - 2e-16 59.4 0.2 2.3e-16 59.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF1644 PF07800.12 KFM74614.1 - 0.073 13.1 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Cation_ATPase_C PF00689.21 KFM74615.1 - 1.1e-42 145.8 7.4 1.7e-42 145.2 7.4 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFM74615.1 - 7e-19 68.9 0.6 2.6e-18 67.1 0.6 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFM74615.1 - 4.2e-15 55.6 0.0 8.3e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFM74615.1 - 0.0017 18.2 1.1 0.0028 17.5 1.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFM74616.1 - 5.9e-38 130.2 0.3 5.1e-37 127.1 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFM74616.1 - 1.5e-19 69.4 0.0 3.3e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM74617.1 - 1.7e-16 60.2 2.2 3.9e-16 59.0 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74617.1 - 8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease An_peroxidase PF03098.15 KFM74618.1 - 8.3e-44 150.0 0.0 9.1e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 KFM74619.1 - 1.5e-43 149.2 0.0 1.6e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Glycos_transf_2 PF00535.26 KFM74622.1 - 1.2e-08 35.0 0.1 1.7e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Fasciclin PF02469.22 KFM74623.1 - 2.7e-95 315.4 3.5 2.2e-25 89.4 0.0 4.2 4 0 0 4 4 4 4 Fasciclin domain DUF4993 PF16384.5 KFM74623.1 - 0.093 11.7 0.0 3.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function Hexokinase_2 PF03727.16 KFM74624.1 - 0.001 18.5 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF4494 PF14902.6 KFM74624.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4494) TPR_11 PF13414.6 KFM74625.1 - 0.02 14.6 0.4 0.04 13.6 0.2 1.6 2 0 0 2 2 2 0 TPR repeat GTP-bdg_N PF13167.6 KFM74625.1 - 0.081 13.6 0.8 0.26 12.0 0.8 1.8 1 1 0 1 1 1 0 GTP-binding GTPase N-terminal TPR_1 PF00515.28 KFM74625.1 - 0.089 12.7 2.0 0.12 12.2 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1699 PF08004.11 KFM74626.1 - 0.017 14.8 2.0 0.019 14.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) WD40_alt PF14077.6 KFM74626.1 - 0.98 9.3 6.1 0.31 10.9 1.7 2.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF2408 PF10303.9 KFM74628.1 - 0.089 13.4 4.4 0.11 13.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Spore_II_R PF09551.10 KFM74628.1 - 0.094 13.2 1.9 0.13 12.7 1.4 1.4 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) V_ATPase_I PF01496.19 KFM74628.1 - 0.78 7.6 5.7 0.86 7.4 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps5 PF09325.10 KFM74629.1 - 0.0016 18.0 1.2 0.0019 17.8 1.2 1.1 1 0 0 1 1 1 1 Vps5 C terminal like HTH_Tnp_Tc3_2 PF01498.18 KFM74630.1 - 3.8e-16 59.1 3.4 5.2e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74630.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74630.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74630.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74630.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Transposase_1 PF01359.18 KFM74631.1 - 7.1e-15 54.6 0.0 1.4e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM74631.1 - 2.2e-06 27.5 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_48 PF17906.1 KFM74631.1 - 4.3e-06 26.7 0.5 1.4e-05 25.1 0.3 2.1 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_24 PF13412.6 KFM74631.1 - 0.0039 16.7 0.6 0.011 15.3 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_9 PF08221.11 KFM74631.1 - 0.012 15.6 0.1 0.029 14.4 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM74631.1 - 0.014 15.6 0.1 0.039 14.2 0.1 1.8 1 0 0 1 1 1 0 Transposase 7tm_1 PF00001.21 KFM74632.1 - 1.7e-48 165.3 22.6 2e-48 165.0 22.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFM74632.1 - 3.5e-07 29.8 11.9 5.7e-07 29.1 11.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFM74632.1 - 3.8e-07 29.7 17.8 4.7e-07 29.4 17.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFM74632.1 - 3.7e-06 26.5 12.7 4.8e-06 26.2 12.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFM74632.1 - 0.015 15.0 19.7 0.013 15.2 18.1 1.7 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFM74632.1 - 0.038 13.7 8.1 0.14 11.9 8.1 1.9 1 1 0 1 1 1 0 Olfactory receptor AAA PF00004.29 KFM74633.1 - 7.9e-78 259.3 0.1 1.7e-45 154.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM74633.1 - 2.2e-17 62.6 0.0 2.2e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 KFM74633.1 - 4.4e-09 36.7 0.0 7.9e-05 22.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFM74633.1 - 1.3e-08 35.4 0.1 0.00034 21.1 0.0 3.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KFM74633.1 - 3.2e-07 30.4 0.0 0.00018 21.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KFM74633.1 - 8.2e-07 29.4 0.3 0.052 13.8 0.1 4.4 2 1 2 4 4 4 1 AAA domain RuvB_N PF05496.12 KFM74633.1 - 2.1e-05 24.3 0.1 0.00035 20.4 0.0 2.9 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFM74633.1 - 2.6e-05 24.3 0.4 0.046 13.7 0.1 3.6 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFM74633.1 - 0.00051 19.7 0.3 1 8.9 0.0 3.2 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 KFM74633.1 - 0.00053 20.3 0.0 0.0024 18.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 KFM74633.1 - 0.00071 18.9 0.0 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase_2 PF01637.18 KFM74633.1 - 0.00075 19.5 0.1 0.01 15.7 0.1 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea TsaE PF02367.17 KFM74633.1 - 0.0028 17.7 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vps4_C PF09336.10 KFM74633.1 - 0.0084 16.1 0.1 7.7 6.6 0.0 3.2 2 1 1 3 3 3 0 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KFM74633.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFM74633.1 - 0.035 13.5 0.2 0.11 11.9 0.1 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFM74633.1 - 0.038 13.7 0.0 0.31 10.7 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 KFM74633.1 - 0.039 14.5 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFM74633.1 - 0.042 13.4 0.0 0.27 10.7 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KFM74633.1 - 0.056 14.0 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KFM74633.1 - 0.058 13.3 0.1 0.32 10.9 0.0 2.2 3 0 0 3 3 3 0 NACHT domain DUF815 PF05673.13 KFM74633.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 KFM74633.1 - 0.059 13.2 0.1 0.43 10.4 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein Zeta_toxin PF06414.12 KFM74633.1 - 0.089 12.1 0.0 0.32 10.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 KFM74633.1 - 0.13 12.0 0.1 0.48 10.1 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM74633.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain HTH_Tnp_Tc3_2 PF01498.18 KFM74635.1 - 4.4e-09 36.5 0.8 7.7e-09 35.7 0.8 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM74635.1 - 3.3e-05 24.4 0.9 6.5e-05 23.5 0.9 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 KFM74635.1 - 0.00075 19.1 0.2 0.0014 18.2 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Apolipoprotein PF01442.18 KFM74635.1 - 0.0021 17.9 11.9 0.003 17.5 11.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lant_dehydr_C PF14028.6 KFM74635.1 - 0.27 10.7 3.3 0.38 10.3 3.3 1.3 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term DUF842 PF05811.13 KFM74635.1 - 0.69 9.6 11.1 2.8 7.6 11.0 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2570 PF10828.8 KFM74635.1 - 1.3 8.8 12.1 0.15 11.9 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) PIN_8 PF18476.1 KFM74635.1 - 1.4 8.7 7.8 1.9 8.3 7.8 1.2 1 0 0 1 1 1 0 PIN like domain AvrM-A PF18241.1 KFM74635.1 - 1.9 8.9 14.2 16 5.8 14.2 2.3 1 1 0 1 1 1 0 Flax-rust effector AvrM-A Paf1 PF03985.13 KFM74635.1 - 2.5 7.0 15.9 3.3 6.6 15.9 1.1 1 0 0 1 1 1 0 Paf1 ING PF12998.7 KFM74635.1 - 3.5 8.3 13.0 4.5 7.9 3.3 2.9 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding FAM25 PF15825.5 KFM74635.1 - 5.8 7.3 21.2 23 5.4 6.0 3.4 1 1 3 4 4 4 0 FAM25 family Pkinase PF00069.25 KFM74636.1 - 1.4e-71 240.9 0.0 1.7e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM74636.1 - 6e-26 91.3 0.0 7.5e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM74636.1 - 1.9e-07 30.7 0.0 4.9e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KFM74636.1 - 0.0006 19.8 0.0 0.013 15.4 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM74636.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFM74636.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 KFM74636.1 - 0.036 14.2 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 ABC1 family FTA2 PF13095.6 KFM74636.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 KASH PF10541.9 KFM74637.1 - 2.7e-13 50.0 5.3 3.1e-13 49.8 2.1 2.5 2 0 0 2 2 2 1 Nuclear envelope localisation domain Spectrin PF00435.21 KFM74637.1 - 0.0078 16.7 15.8 1.1 9.8 0.3 5.1 4 0 0 4 4 4 3 Spectrin repeat DASH_Dam1 PF08653.10 KFM74637.1 - 0.17 11.7 2.1 28 4.6 0.1 3.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 Xan_ur_permease PF00860.20 KFM74638.1 - 1.1e-61 208.8 11.7 1.4e-61 208.4 11.7 1.0 1 0 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 KFM74639.1 - 5.4e-19 68.2 5.9 7.8e-19 67.6 5.9 1.2 1 0 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 KFM74640.1 - 6.3e-61 206.2 16.3 8.7e-61 205.7 16.3 1.1 1 0 0 1 1 1 1 Permease family RabGAP-TBC PF00566.18 KFM74642.1 - 0.058 13.0 0.1 0.087 12.5 0.1 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DDE_3 PF13358.6 KFM74643.1 - 5.8e-16 58.6 0.1 6.6e-15 55.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74643.1 - 8.6e-16 57.9 6.5 1.7e-15 57.0 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM74643.1 - 0.00082 19.9 1.5 0.00082 19.9 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain DUF5589 PF17672.1 KFM74643.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5589) ARD PF03079.14 KFM74644.1 - 1.2e-52 178.3 0.1 1.3e-52 178.1 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KFM74644.1 - 6.4e-07 29.0 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KFM74644.1 - 7.1e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KFM74644.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Cupin Cas9_b_hairpin PF17893.1 KFM74644.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain zf-H2C2_2 PF13465.6 KFM74645.1 - 3.6e-110 355.9 97.2 1e-09 38.4 0.3 16.1 15 1 1 16 16 16 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74645.1 - 9.9e-66 214.7 110.1 8.6e-07 29.1 1.0 15.0 15 0 0 15 15 15 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74645.1 - 6.4e-53 172.8 108.6 7.4e-05 23.3 0.7 15.0 15 0 0 15 15 15 14 C2H2-type zinc finger zf-met PF12874.7 KFM74645.1 - 4e-29 100.1 102.9 0.00078 19.8 0.6 14.4 15 0 0 15 15 14 13 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.15 KFM74645.1 - 7.2e-22 77.2 39.3 0.0026 17.8 0.2 12.3 8 3 4 12 12 12 8 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 KFM74645.1 - 9.6e-20 70.1 87.3 0.00029 20.8 0.2 14.0 14 0 0 14 14 14 9 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM74645.1 - 9.4e-19 66.9 69.4 0.068 12.9 0.2 14.6 15 0 0 15 15 15 10 C2H2-type zinc-finger domain BolA PF01722.18 KFM74645.1 - 7.3e-15 55.0 20.9 0.057 13.7 0.3 10.3 2 1 3 7 7 7 5 BolA-like protein zf-C2H2_jaz PF12171.8 KFM74645.1 - 5.5e-13 48.8 73.5 0.059 13.7 0.2 13.9 14 0 0 14 14 14 7 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM74645.1 - 9.2e-12 44.5 86.0 0.12 12.2 3.3 13.5 13 0 0 13 13 13 8 zinc-finger C2H2-type Tox-HNH-HHH PF15637.6 KFM74645.1 - 7.7e-10 38.9 0.9 0.24 11.6 0.0 6.0 1 1 5 7 7 7 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif GAGA PF09237.11 KFM74645.1 - 0.00019 21.2 27.7 0.36 10.7 0.0 9.3 3 2 8 11 11 11 1 GAGA factor zf-C2H2_9 PF16293.5 KFM74645.1 - 0.0007 19.4 61.2 1.9 8.4 0.1 13.3 4 3 10 14 14 14 2 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 KFM74645.1 - 0.011 15.3 55.0 1.5 8.5 0.0 12.2 13 0 0 13 13 13 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM74645.1 - 0.065 12.9 81.3 0.27 10.9 0.2 13.7 4 3 11 15 15 15 0 MYST family zinc finger domain DUF3396 PF11876.8 KFM74645.1 - 0.069 12.6 0.0 17 4.8 0.0 3.7 2 1 4 6 6 6 0 Protein of unknown function (DUF3396) TRAF6_Z2 PF18048.1 KFM74645.1 - 0.076 13.1 53.2 0.55 10.4 1.0 12.0 13 0 0 13 13 13 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2HC_2 PF13913.6 KFM74645.1 - 0.23 11.4 46.7 23 5.0 0.0 12.3 13 0 0 13 13 13 0 zinc-finger of a C2HC-type DUF5330 PF17264.2 KFM74645.1 - 0.28 11.2 32.2 19 5.4 0.1 10.6 12 0 0 12 12 11 0 Family of unknown function (DUF5330) zf-C2H2_2 PF12756.7 KFM74645.1 - 1.7 9.0 87.7 2.4 8.5 0.6 13.1 1 1 9 12 12 11 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFM74645.1 - 3.7 7.7 55.7 10 6.3 4.7 9.6 3 1 9 12 12 12 0 Zinc ribbon domain zf-FPG_IleRS PF06827.14 KFM74645.1 - 3.9 7.4 41.8 56 3.7 0.6 11.7 13 0 0 13 13 13 0 Zinc finger found in FPG and IleRS HTH_36 PF13730.6 KFM74646.1 - 0.072 13.1 0.7 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain IMD PF08397.11 KFM74647.1 - 3.8e-09 36.3 0.1 3.9e-09 36.2 0.1 1.0 1 0 0 1 1 1 1 IRSp53/MIM homology domain DNA_III_psi PF03603.13 KFM74652.1 - 0.14 12.4 0.0 0.15 12.3 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase III psi subunit PH_11 PF15413.6 KFM74653.1 - 0.045 14.2 0.2 6 7.3 0.0 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain Gal-bind_lectin PF00337.22 KFM74654.1 - 4.3e-68 227.0 0.0 7.1e-24 83.9 0.0 3.0 3 0 0 3 3 3 3 Galactoside-binding lectin CAF1 PF04857.20 KFM74655.1 - 1.7e-85 287.0 6.2 1.7e-85 287.0 6.2 1.4 2 0 0 2 2 2 1 CAF1 family ribonuclease RNA_bind PF08675.11 KFM74655.1 - 1.3e-24 86.0 0.0 2.8e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding domain R3H PF01424.22 KFM74655.1 - 2.7e-06 27.3 0.1 6e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 R3H domain DUF2682 PF10909.8 KFM74655.1 - 0.0031 18.0 0.2 0.059 13.9 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2682) DUF4473 PF14747.6 KFM74655.1 - 0.067 13.7 1.1 0.22 12.1 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) TetR_C_17 PF17922.1 KFM74655.1 - 0.13 12.4 0.3 5.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Peptidase_A17 PF05380.13 KFM74656.1 - 1.1e-15 58.0 0.1 1.6e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Pao retrotransposon peptidase RNase_H PF00075.24 KFM74656.1 - 0.0062 16.7 0.0 0.0075 16.5 0.0 1.2 1 0 0 1 1 1 1 RNase H BBIP10 PF14777.6 KFM74656.1 - 0.13 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 DUF1433 PF07252.11 KFM74656.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1433) ABC2_membrane PF01061.24 KFM74661.1 - 3.4e-16 59.3 16.3 3.4e-16 59.3 16.3 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFM74661.1 - 1.2e-07 32.3 0.0 2.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KFM74661.1 - 0.00067 18.9 2.6 0.0011 18.1 2.6 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.12 KFM74661.1 - 0.76 9.7 2.8 2 8.4 0.2 2.8 3 0 0 3 3 3 0 CDR ABC transporter DDE_3 PF13358.6 KFM74662.1 - 2.7e-11 43.4 0.0 4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.32 KFM74666.1 - 5.9e-13 49.1 16.3 0.0042 17.9 1.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM74666.1 - 3.7e-11 43.2 0.0 0.015 15.6 0.0 4.3 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain MraZ PF02381.18 KFM74666.1 - 0.0048 16.9 0.0 0.12 12.4 0.0 2.8 3 0 0 3 3 3 1 MraZ protein, putative antitoxin-like BBS2_Mid PF14783.6 KFM74666.1 - 0.16 12.1 0.0 7.9 6.6 0.0 2.9 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Tmemb_9 PF05434.11 KFM74667.1 - 1e-60 203.8 3.9 1.6e-60 203.2 3.9 1.3 1 0 0 1 1 1 1 TMEM9 Sigma_reg_N PF13800.6 KFM74667.1 - 0.024 14.9 2.8 0.23 11.8 0.2 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal PGG PF13962.6 KFM74667.1 - 0.042 13.7 1.1 3.1 7.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function 7tm_1 PF00001.21 KFM74667.1 - 0.069 12.5 1.2 0.075 12.3 0.1 1.6 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Cadherin_C_2 PF16492.5 KFM74667.1 - 0.095 13.5 0.1 1.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Gemini_mov PF01708.16 KFM74667.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein Tetraspanin PF00335.20 KFM74667.1 - 0.81 9.4 6.0 0.097 12.4 1.6 1.6 1 1 1 2 2 2 0 Tetraspanin family DUF2852 PF11014.8 KFM74668.1 - 0.027 14.6 0.4 0.04 14.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) SPX PF03105.19 KFM74668.1 - 0.56 10.1 5.5 1.2 9.0 5.5 1.6 1 1 0 1 1 1 0 SPX domain DUF1298 PF06974.13 KFM74669.1 - 1.9e-26 92.7 0.1 4.8e-26 91.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 KFM74669.1 - 3.6e-10 40.1 0.0 7.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1427 PF07235.11 KFM74669.1 - 0.088 12.8 0.3 0.22 11.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) GAS2 PF02187.17 KFM74671.1 - 8.6e-25 86.6 0.5 1.9e-24 85.5 0.5 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFM74671.1 - 3.6e-13 49.6 0.2 1e-12 48.2 0.2 1.8 1 1 0 1 1 1 1 Calponin homology (CH) domain Aldedh PF00171.22 KFM74672.1 - 1.3e-82 277.8 0.0 6.8e-49 166.6 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFM74672.1 - 3.4e-08 33.2 0.1 1.5e-07 31.1 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Aldedh PF00171.22 KFM74673.1 - 2e-11 43.1 0.0 2.4e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YihI PF04220.12 KFM74673.1 - 0.078 12.7 0.1 0.097 12.4 0.1 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) PAN_1 PF00024.26 KFM74676.1 - 3.8e-26 90.9 21.1 1.5e-12 47.2 2.8 3.0 3 0 0 3 3 3 3 PAN domain ALO PF04030.14 KFM74677.1 - 2.1e-79 267.0 4.4 2.4e-79 266.9 4.4 1.0 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase p450 PF00067.22 KFM74679.1 - 1.7e-106 356.8 0.0 5.1e-75 253.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Phosphodiest PF01663.22 KFM74681.1 - 4e-17 62.8 0.0 4.6e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Phosphodiest PF01663.22 KFM74682.1 - 1e-34 120.7 0.1 1.2e-34 120.4 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFM74682.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily PglZ PF08665.12 KFM74682.1 - 0.025 14.7 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 PglZ domain HTH_48 PF17906.1 KFM74683.1 - 8.5e-10 38.6 0.2 1.7e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM74683.1 - 0.013 16.1 0.3 0.1 13.3 0.0 2.5 2 1 0 2 2 2 0 Homeodomain-like domain Ribosomal_L34e PF01199.18 KFM74683.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.3 3 1 0 3 3 3 0 Ribosomal protein L34e DDE_3 PF13358.6 KFM74684.1 - 4.5e-16 58.9 0.2 6.3e-15 55.2 0.0 2.6 1 1 2 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74684.1 - 8.2e-16 58.0 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM74684.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM74684.1 - 0.0027 17.4 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM74684.1 - 0.017 15.3 0.1 0.067 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM74684.1 - 0.032 14.3 2.6 0.036 14.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix Toxin_7 PF05980.12 KFM74685.1 - 0.2 11.9 3.9 0.53 10.6 0.4 2.2 2 0 0 2 2 2 0 Toxin 7 UPRTase PF14681.6 KFM74686.1 - 8.2e-36 123.4 0.0 8.9e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 KFM74687.1 - 1.9e-58 197.5 0.1 2.3e-58 197.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFM74687.1 - 2.8e-07 31.1 0.0 4.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KFM74687.1 - 3.8e-05 23.6 0.0 6.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein CoaE PF01121.20 KFM74687.1 - 4.7e-05 23.1 0.6 0.00025 20.8 0.6 1.9 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 KFM74687.1 - 9.5e-05 22.6 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFM74687.1 - 0.00089 19.7 0.6 0.0084 16.5 0.6 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFM74687.1 - 0.001 18.8 0.6 0.35 10.6 0.0 2.2 1 1 0 2 2 2 2 Cytidylate kinase Zeta_toxin PF06414.12 KFM74687.1 - 0.014 14.7 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.14 KFM74687.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 KFM74687.1 - 0.11 12.4 0.3 0.32 10.9 0.0 2.2 2 1 0 2 2 2 0 Adenylylsulphate kinase HTH_Tnp_Tc3_2 PF01498.18 KFM74688.1 - 1.9e-12 47.2 1.2 3.2e-12 46.5 1.2 1.4 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 KFM74688.1 - 0.008 15.9 0.2 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM74688.1 - 0.03 14.3 0.1 0.074 13.1 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_IclR PF09339.10 KFM74688.1 - 0.032 14.0 0.6 0.063 13.1 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 KFM74688.1 - 0.045 13.6 1.5 1.7 8.5 0.1 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM74688.1 - 0.055 13.4 0.3 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM74688.1 - 0.069 12.7 0.1 0.41 10.2 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM74688.1 - 0.11 12.3 1.3 0.18 11.7 0.2 1.9 2 0 0 2 2 2 0 Homeodomain-like domain RSB_motif PF16294.5 KFM74689.1 - 1.2e-18 67.2 23.0 1.2e-18 67.2 23.0 9.0 4 3 2 6 6 6 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 KFM74689.1 - 1.2e-09 37.7 3.8 1.2e-09 37.7 3.8 1.9 2 0 0 2 2 2 1 SAP domain RRM_1 PF00076.22 KFM74689.1 - 1.6e-06 27.8 0.0 7e-06 25.8 0.0 2.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4686 PF15742.5 KFM74690.1 - 8.3e-05 21.9 50.0 8.3e-05 21.9 50.0 2.6 1 1 0 2 2 2 1 Domain of unknown function (DUF4686) DUF4407 PF14362.6 KFM74690.1 - 0.0013 18.2 15.2 0.0013 18.2 15.2 3.1 1 1 0 3 3 3 1 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 KFM74690.1 - 0.0016 18.7 21.7 0.0016 18.7 21.7 5.3 2 1 3 5 5 5 2 JNK_SAPK-associated protein-1 Spc7 PF08317.11 KFM74690.1 - 0.0027 16.7 26.2 0.0027 16.7 26.2 3.8 2 1 1 3 3 3 1 Spc7 kinetochore protein DUF3450 PF11932.8 KFM74690.1 - 0.0059 15.9 12.1 0.0059 15.9 12.1 5.0 2 1 3 5 5 5 2 Protein of unknown function (DUF3450) DASH_Hsk3 PF08227.11 KFM74690.1 - 1.2 9.5 0.0 1.2 9.5 0.0 4.7 5 2 0 5 5 5 0 DASH complex subunit Hsk3 like FtsL PF04999.13 KFM74690.1 - 1.7 8.7 21.5 3.9 7.6 1.2 4.0 3 1 0 3 3 3 0 Cell division protein FtsL Cyt-b5 PF00173.28 KFM74691.1 - 3.1e-25 88.1 0.0 4e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NOB1_Zn_bind PF08772.11 KFM74693.1 - 1.8e-30 104.9 1.5 3.3e-30 104.1 1.5 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KFM74693.1 - 1.2e-29 102.6 0.0 4.1e-29 100.9 0.0 1.9 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 KFM74693.1 - 0.028 14.1 0.3 0.99 9.1 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF1272 PF06906.11 KFM74693.1 - 0.054 13.6 0.5 0.12 12.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 KFM74693.1 - 0.055 13.5 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 KFM74693.1 - 0.11 12.5 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 Nudix N-terminal HypA PF01155.19 KFM74693.1 - 0.14 12.2 0.8 0.59 10.2 0.2 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NTF2 PF02136.20 KFM74694.1 - 6.4e-34 117.1 0.1 1.2e-33 116.2 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KFM74694.1 - 8.2e-13 48.0 0.1 3.4e-12 46.0 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM74694.1 - 5.6e-07 29.6 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif DUF1179 PF06678.11 KFM74694.1 - 3 7.9 10.7 1.2 9.2 4.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1179) BCA_ABC_TP_C PF12399.8 KFM74695.1 - 0.24 11.4 0.9 0.54 10.2 0.2 2.0 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter CUB PF00431.20 KFM74696.1 - 1.4e-41 141.3 1.6 4.9e-29 100.9 0.1 2.2 2 0 0 2 2 2 2 CUB domain HTH_Tnp_Tc3_2 PF01498.18 KFM74697.1 - 5e-16 58.7 3.5 6.1e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74697.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74697.1 - 3.1e-07 30.0 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74697.1 - 0.0027 17.4 0.6 0.0081 15.9 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM74697.1 - 0.03 14.5 0.4 0.096 12.8 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM74697.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM74698.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74698.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74698.1 - 1.4e-06 28.0 1.2 4.8e-06 26.2 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74698.1 - 0.0034 17.1 0.6 0.0096 15.7 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM74699.1 - 1.2e-18 67.1 1.7 1.8e-18 66.5 1.7 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74699.1 - 3.1e-16 59.5 0.0 1.5e-15 57.2 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM74699.1 - 0.028 15.0 1.1 0.082 13.5 0.3 2.1 2 0 0 2 2 2 0 Homeodomain-like domain MADF_DNA_bdg PF10545.9 KFM74700.1 - 7.9e-16 58.1 4.2 7.9e-16 58.1 4.2 2.0 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 KFM74700.1 - 3.6e-05 23.5 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 BESS motif Myb_DNA-bind_5 PF13873.6 KFM74700.1 - 7.2e-05 22.8 0.6 7.2e-05 22.8 0.6 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF3533 PF12051.8 KFM74700.1 - 0.22 10.4 0.1 0.27 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) WAP PF00095.21 KFM74701.1 - 0.055 13.9 16.1 0.11 12.9 16.1 1.5 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.21 KFM74702.1 - 0.26 11.7 18.2 0.43 11.0 18.2 1.4 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.21 KFM74703.1 - 0.00062 20.1 17.0 0.00078 19.8 17.0 1.2 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.21 KFM74704.1 - 0.0015 18.9 14.4 0.0022 18.3 14.4 1.3 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' DDE_3 PF13358.6 KFM74705.1 - 4.9e-10 39.3 0.0 8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MarR_2 PF12802.7 KFM74705.1 - 0.0019 18.0 0.3 0.024 14.5 0.0 2.5 2 1 1 3 3 3 1 MarR family PAX PF00292.18 KFM74705.1 - 0.014 15.4 0.0 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain HTH_Crp_2 PF13545.6 KFM74705.1 - 0.051 13.5 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain N_BRCA1_IG PF16158.5 KFM74708.1 - 2.6e-33 114.8 0.4 4.5e-33 114.0 0.4 1.4 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 KFM74708.1 - 1.6e-10 40.7 0.1 3.5e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UPF0444 PF15475.6 KFM74709.1 - 2e-06 28.0 8.7 6.4e-06 26.4 8.3 1.8 1 1 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 WD40 PF00400.32 KFM74712.1 - 0.00074 20.3 1.2 0.96 10.4 0.4 3.7 2 1 0 2 2 2 2 WD domain, G-beta repeat PRORP PF16953.5 KFM74714.1 - 2.4e-67 227.0 2.1 2.6e-67 226.8 1.2 1.5 1 1 1 2 2 2 1 Protein-only RNase P BACK PF07707.15 KFM74714.1 - 0.0012 18.9 1.9 0.39 10.8 0.1 3.2 2 1 0 2 2 2 2 BTB And C-terminal Kelch DUF3437 PF11919.8 KFM74714.1 - 0.0099 15.8 0.1 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) ATP-synt_Eps PF04627.13 KFM74714.1 - 0.056 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain AvrM_N PF18247.1 KFM74714.1 - 0.12 12.4 0.3 0.48 10.4 0.0 2.2 2 0 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain zf-H2C2_2 PF13465.6 KFM74715.1 - 5.4e-90 292.2 119.2 2.7e-08 33.8 0.6 17.8 18 0 0 18 18 18 17 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74715.1 - 1.5e-71 233.0 159.4 3.8e-06 27.0 0.3 17.3 17 0 0 17 17 17 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74715.1 - 2e-52 171.3 145.5 0.00034 21.2 0.2 17.2 17 0 0 17 17 17 17 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM74715.1 - 1.7e-26 91.7 114.8 6.5e-05 22.8 0.5 17.7 17 0 0 17 17 17 12 C2H2-type zinc finger zf-met PF12874.7 KFM74715.1 - 2.5e-17 62.7 123.9 0.023 15.1 0.3 17.7 16 1 1 17 17 17 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM74715.1 - 1.2e-10 41.3 107.9 0.024 14.9 0.0 17.3 16 1 1 17 17 17 8 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM74715.1 - 0.016 15.5 17.5 2.5 8.5 3.2 6.7 4 2 2 6 6 6 0 BolA-like protein zf-C2H2_2 PF12756.7 KFM74715.1 - 0.85 10.0 109.0 2.7 8.4 3.0 12.4 1 1 9 11 11 11 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM74715.1 - 7.9 6.6 45.3 0.95 9.5 2.4 9.4 6 4 1 7 7 7 0 Adenylate kinase, active site lid zf-H2C2_2 PF13465.6 KFM74716.1 - 1.9e-26 91.3 52.3 3.8e-06 27.1 0.6 7.8 6 1 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74716.1 - 1.7e-21 75.4 58.9 0.00021 21.5 0.6 7.7 8 0 0 8 8 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74716.1 - 1e-18 66.4 48.7 0.00075 20.1 0.3 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM74716.1 - 3.4e-12 46.0 56.2 0.0038 17.2 0.2 8.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74716.1 - 2.6e-08 33.9 33.7 0.012 15.8 0.0 7.4 6 1 1 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM74716.1 - 2e-05 24.8 41.3 1 9.9 0.8 7.7 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFM74716.1 - 0.0019 17.7 22.0 0.38 10.4 0.0 6.7 7 0 0 7 7 7 2 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KFM74716.1 - 0.0052 16.6 12.7 1 9.2 0.4 4.9 5 0 0 5 5 5 2 GAGA factor HJURP_mid PF12346.8 KFM74716.1 - 0.027 14.9 0.6 0.027 14.9 0.6 1.9 1 1 1 2 2 2 0 Holliday junction recognition protein-associated repeat DUF2180 PF09947.9 KFM74716.1 - 0.028 14.4 1.0 0.028 14.4 1.0 3.3 3 2 0 3 3 2 0 Uncharacterized protein conserved in archaea (DUF2180) GATA PF00320.27 KFM74716.1 - 0.074 12.7 4.5 2.1 8.0 0.1 3.4 3 1 0 3 3 3 0 GATA zinc finger ECH_2 PF16113.5 KFM74716.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase zf-C2H2_2 PF12756.7 KFM74716.1 - 0.14 12.5 34.8 1.1 9.6 0.2 6.2 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) Rpr2 PF04032.16 KFM74716.1 - 0.34 11.2 24.5 2 8.8 4.5 4.1 2 2 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_15 PF17032.5 KFM74716.1 - 0.79 10.5 24.4 0.34 11.7 5.5 3.8 2 2 1 3 3 3 0 zinc-ribbon family Sprouty PF05210.13 KFM74716.1 - 1.6 9.1 18.8 0.15 12.5 3.2 3.4 3 1 1 4 4 4 0 Sprouty protein (Spry) DUF4428 PF14471.6 KFM74716.1 - 2.5 8.1 19.9 5.4 7.0 2.8 4.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4428) C1_2 PF03107.16 KFM74716.1 - 4.1 7.8 33.2 20 5.6 2.5 6.5 2 2 3 5 5 5 0 C1 domain HNH_5 PF14279.6 KFM74716.1 - 4.4 7.3 24.0 0.13 12.1 1.2 5.2 6 1 0 6 6 6 0 HNH endonuclease FYDLN_acid PF09538.10 KFM74716.1 - 5.7 7.7 7.0 13 6.6 0.1 3.9 2 2 0 3 3 3 0 Protein of unknown function (FYDLN_acid) YceD PF02620.17 KFM74716.1 - 6.9 6.8 6.3 4.1 7.5 0.1 3.5 3 2 2 5 5 5 0 Large ribosomal RNA subunit accumulation protein YceD Zn-ribbon_8 PF09723.10 KFM74716.1 - 8 6.7 14.2 1.3 9.2 0.4 4.2 4 1 0 4 4 4 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 KFM74718.1 - 5.9e-70 228.8 76.9 2.5e-09 37.1 0.7 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74718.1 - 2.6e-42 141.0 97.1 4.6e-06 26.8 0.5 12.2 13 0 0 13 13 12 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74718.1 - 1.2e-35 119.1 90.8 0.00019 22.0 0.7 12.0 12 0 0 12 12 12 10 C2H2-type zinc finger zf-met PF12874.7 KFM74718.1 - 9e-20 70.4 87.6 0.0025 18.1 0.8 12.4 12 0 0 12 12 12 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74718.1 - 1.8e-16 59.7 84.6 0.00052 19.9 0.8 11.9 11 1 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74718.1 - 2.1e-15 56.6 82.0 0.0025 18.0 1.9 11.7 11 1 1 12 12 12 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM74718.1 - 2.1e-12 47.2 11.3 0.26 11.6 0.3 8.3 1 1 7 8 8 8 4 BolA-like protein zf-H2C2_5 PF13909.6 KFM74718.1 - 4.9e-08 32.6 56.9 0.0053 16.5 0.5 10.1 10 0 0 10 10 10 5 C2H2-type zinc-finger domain GAGA PF09237.11 KFM74718.1 - 0.022 14.6 29.3 0.15 11.9 0.5 7.6 4 3 5 9 9 9 0 GAGA factor Zf_RING PF16744.5 KFM74718.1 - 0.05 13.7 0.4 0.05 13.7 0.4 9.2 3 1 7 10 10 10 0 KIAA1045 RING finger zf-C2H2_11 PF16622.5 KFM74718.1 - 0.21 11.4 0.1 0.21 11.4 0.1 8.0 9 0 0 9 9 9 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM74718.1 - 0.46 10.5 49.5 9.6 6.2 0.1 11.5 11 1 0 11 11 11 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFM74718.1 - 0.9 9.9 70.9 0.68 10.3 0.7 8.7 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM74718.1 - 9 7.1 54.1 1.9 9.3 2.4 6.1 1 1 5 6 6 6 0 zinc-ribbon family zf-H2C2_2 PF13465.6 KFM74719.1 - 7.4e-70 228.5 52.0 5.2e-09 36.1 0.1 10.1 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74719.1 - 7.7e-48 158.4 85.2 3.3e-07 30.4 0.4 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74719.1 - 2e-33 112.2 75.2 0.00032 21.3 0.8 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM74719.1 - 1.9e-18 66.2 68.9 0.016 15.6 2.3 10.3 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74719.1 - 1.2e-17 63.4 64.4 4.8e-07 29.6 0.9 10.4 10 1 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74719.1 - 1.8e-14 53.5 54.5 0.028 14.7 0.2 10.3 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM74719.1 - 3.3e-07 29.9 51.4 0.1 12.4 1.0 8.9 9 0 0 9 9 9 6 C2H2-type zinc-finger domain GAGA PF09237.11 KFM74719.1 - 3e-06 26.9 19.4 0.4 10.5 0.1 6.2 3 2 5 8 8 7 4 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM74719.1 - 7.5e-05 22.7 36.9 5.1 7.2 0.1 9.8 10 0 0 10 10 10 1 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM74719.1 - 9e-05 22.4 33.7 2.2 8.3 1.9 7.1 4 3 2 6 6 6 3 Adenylate kinase, active site lid BolA PF01722.18 KFM74719.1 - 0.00032 20.9 13.4 0.46 10.8 0.3 5.6 3 2 2 5 5 5 1 BolA-like protein zf-C2HC_2 PF13913.6 KFM74719.1 - 0.00046 20.0 40.8 0.38 10.7 0.3 10.1 10 1 0 10 10 10 1 zinc-finger of a C2HC-type FYVE PF01363.21 KFM74719.1 - 0.028 14.6 11.7 0.028 14.6 11.7 6.6 1 1 4 5 5 4 0 FYVE zinc finger zf-C2HE PF16278.5 KFM74719.1 - 0.029 14.8 0.5 0.029 14.8 0.5 7.3 3 2 3 6 6 5 0 C2HE / C2H2 / C2HC zinc-binding finger Mga PF05043.13 KFM74719.1 - 0.09 13.4 0.1 25 5.6 0.0 3.8 2 1 2 4 4 4 0 Mga helix-turn-helix domain DUF3268 PF11672.8 KFM74719.1 - 0.11 12.8 33.5 0.08 13.3 1.8 5.0 3 1 3 6 6 6 0 zinc-finger-containing domain zf-MYST PF17772.1 KFM74719.1 - 0.21 11.2 46.5 1.4 8.6 0.5 9.0 3 2 7 10 10 10 0 MYST family zinc finger domain Ta0938 PF11494.8 KFM74719.1 - 0.26 11.6 33.2 1.6 9.1 0.3 7.6 1 1 6 7 7 7 0 Ta0938 zf-trcl PF13451.6 KFM74719.1 - 2.3 8.2 41.9 4.8 7.1 0.9 8.7 9 0 0 9 9 9 0 Probable zinc-ribbon domain zf-CCHC_2 PF13696.6 KFM74719.1 - 5.9 6.8 49.9 2.1 8.2 0.5 9.7 10 0 0 10 10 10 0 Zinc knuckle Zn-ribbon_8 PF09723.10 KFM74719.1 - 6.1 7.1 37.0 1.6 8.9 1.1 7.0 3 2 2 6 6 6 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM74719.1 - 6.1 7.7 39.1 6.5 7.6 2.9 5.1 2 1 2 4 4 4 0 zinc-ribbon family C5HCH PF17982.1 KFM74719.1 - 8.6 6.6 40.0 13 6.1 1.0 9.2 9 1 0 10 10 10 0 NSD Cys-His rich domain zf_UBZ PF18439.1 KFM74719.1 - 8.9 6.0 46.9 3.9 7.2 0.1 9.6 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger SCAN PF02023.17 KFM74720.1 - 2.2e-07 30.6 0.1 3.2e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 SCAN domain MFS_1 PF07690.16 KFM74722.1 - 1.8e-17 63.3 15.4 8.2e-14 51.3 9.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM74722.1 - 2e-06 26.9 6.4 2e-06 26.9 6.4 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter zf-H2C2_2 PF13465.6 KFM74724.1 - 1.5e-21 75.8 35.2 6.4e-08 32.7 0.1 6.3 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74724.1 - 1e-19 69.8 38.2 3.9e-05 23.9 0.3 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74724.1 - 1.4e-18 66.0 33.0 0.00011 22.7 1.3 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM74724.1 - 1.9e-12 46.8 27.2 0.0054 16.7 1.2 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM74724.1 - 3.2e-11 43.2 23.8 0.00091 19.5 1.8 5.3 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM74724.1 - 7.6e-10 38.8 20.3 0.032 14.5 1.6 5.3 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM74724.1 - 2.5e-08 33.6 24.5 0.011 15.6 0.4 5.7 5 1 0 5 5 5 3 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFM74724.1 - 1.3e-05 24.9 12.9 0.51 10.2 0.2 4.8 2 2 3 5 5 5 3 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFM74724.1 - 1.5e-05 24.6 24.9 0.021 14.6 0.2 5.2 5 0 0 5 5 5 3 zinc-finger C2H2-type FYVE PF01363.21 KFM74724.1 - 0.0057 16.8 8.9 0.0057 16.8 8.9 3.8 1 1 2 3 3 3 1 FYVE zinc finger Zn-ribbon_8 PF09723.10 KFM74724.1 - 0.013 15.6 14.5 0.027 14.6 0.8 4.2 3 2 0 3 3 3 0 Zinc ribbon domain Rad50_zn_hook PF04423.14 KFM74724.1 - 0.096 12.5 0.0 0.096 12.5 0.0 3.6 4 2 1 5 5 5 0 Rad50 zinc hook motif zf_UBZ PF18439.1 KFM74724.1 - 0.098 12.3 19.7 6.6 6.4 0.2 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 KFM74724.1 - 0.21 11.9 0.1 0.21 11.9 0.1 3.7 5 1 0 5 5 3 0 zinc-ribbon YceD PF02620.17 KFM74724.1 - 0.36 10.9 4.8 9.9 6.3 0.0 3.2 1 1 2 4 4 4 0 Large ribosomal RNA subunit accumulation protein YceD Ribosomal_L28 PF00830.19 KFM74724.1 - 0.37 11.0 16.0 32 4.8 2.3 5.0 4 1 0 4 4 4 0 Ribosomal L28 family DUF2256 PF10013.9 KFM74724.1 - 0.37 10.9 19.9 2.8 8.1 0.3 5.2 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM74724.1 - 0.65 10.0 21.0 6.5 6.8 2.4 4.6 3 2 0 3 3 3 0 Adenylate kinase, active site lid DUF4428 PF14471.6 KFM74724.1 - 1 9.4 19.7 13 5.8 7.9 5.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4428) zf-C2H2_2 PF12756.7 KFM74724.1 - 1.3 9.4 23.3 23 5.4 9.2 4.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Prim_Zn_Ribbon PF08273.12 KFM74724.1 - 2.1 8.7 18.5 6.5 7.1 0.1 5.0 5 0 0 5 5 5 0 Zinc-binding domain of primase-helicase DUF2225 PF09986.9 KFM74724.1 - 3.1 7.5 20.1 2.7 7.7 1.4 4.1 3 2 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_8 PF15909.5 KFM74724.1 - 5 7.5 18.5 3 8.2 9.8 2.9 1 1 2 3 3 3 0 C2H2-type zinc ribbon HTH_23 PF13384.6 KFM74725.1 - 2.8e-08 33.3 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KFM74725.1 - 8.3e-07 28.6 0.1 9.2e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 KFM74725.1 - 3.2e-06 27.0 0.1 4.2e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_50 PF18024.1 KFM74725.1 - 2.1e-05 24.1 0.2 2.8e-05 23.6 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KFM74725.1 - 2.5e-05 24.0 0.2 3.4e-05 23.5 0.2 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM74725.1 - 2.8e-05 23.4 0.0 3.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KFM74725.1 - 3.8e-05 23.7 0.0 5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM74725.1 - 0.00035 20.0 0.1 0.00044 19.7 0.1 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 UPF0122 PF04297.14 KFM74725.1 - 0.00061 20.0 0.0 0.00069 19.8 0.0 1.1 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_24 PF13412.6 KFM74725.1 - 0.0016 18.0 0.1 0.0018 17.8 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_IS630 PF01710.16 KFM74725.1 - 0.0022 18.0 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Transposase Mor PF08765.11 KFM74725.1 - 0.0087 16.0 0.4 0.01 15.8 0.4 1.2 1 0 0 1 1 1 1 Mor transcription activator family HTH_7 PF02796.15 KFM74725.1 - 0.0098 16.0 0.2 0.016 15.3 0.2 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain of resolvase TnsD PF15978.5 KFM74725.1 - 0.0098 14.9 0.1 0.0098 14.9 0.1 1.0 1 0 0 1 1 1 1 Tn7-like transposition protein D HTH_1 PF00126.27 KFM74725.1 - 0.011 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_1 PF01527.20 KFM74725.1 - 0.011 16.0 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 0 Transposase DUF3791 PF12668.7 KFM74725.1 - 0.034 14.2 0.1 0.05 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) HTH_40 PF14493.6 KFM74725.1 - 0.04 14.4 0.1 0.045 14.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 KFM74725.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix ASC PF00858.24 KFM74726.1 - 5.4e-12 45.4 0.2 6e-12 45.3 0.2 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel VirB8 PF04335.13 KFM74727.1 - 0.045 13.6 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 VirB8 protein EGF_Tenascin PF18720.1 KFM74728.1 - 3.4e-07 30.2 12.2 1.4e-05 25.0 4.2 2.4 3 0 0 3 3 3 2 Tenascin EGF domain EGF_2 PF07974.13 KFM74728.1 - 2.1e-06 28.0 25.0 0.00024 21.4 7.8 3.2 3 0 0 3 3 3 2 EGF-like domain I-EGF_1 PF18372.1 KFM74728.1 - 0.00022 21.2 19.8 0.0022 18.0 6.9 3.4 3 0 0 3 3 3 2 Integrin beta epidermal growth factor like domain 1 Laminin_EGF PF00053.24 KFM74728.1 - 0.18 12.0 17.4 0.54 10.5 1.9 2.7 1 1 1 2 2 2 0 Laminin EGF domain EGF_alliinase PF04863.13 KFM74728.1 - 2.2 8.7 20.7 1.2 9.6 6.8 3.6 2 1 1 3 3 3 0 Alliinase EGF-like domain DSL PF01414.19 KFM74728.1 - 6.5 7.1 20.1 0.82 10.0 14.6 2.3 1 1 1 2 2 2 0 Delta serrate ligand Toxin_6 PF05453.12 KFM74728.1 - 7.5 7.1 13.5 0.47 10.9 1.5 3.4 3 1 0 3 3 3 0 BmTXKS1/BmP02 toxin family EGF_2 PF07974.13 KFM74729.1 - 1.2e-12 48.0 93.1 6e-05 23.3 12.2 6.1 6 0 0 6 6 6 5 EGF-like domain CarboxypepD_reg PF13620.6 KFM74729.1 - 0.00059 20.1 0.1 0.00083 19.6 0.1 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain EGF PF00008.27 KFM74729.1 - 0.00071 19.8 6.9 0.00071 19.8 6.9 6.4 7 0 0 7 7 7 2 EGF-like domain EGF_Tenascin PF18720.1 KFM74729.1 - 0.98 9.5 51.2 0.48 10.5 10.4 6.1 5 1 0 5 5 5 0 Tenascin EGF domain Urm1 PF09138.11 KFM74731.1 - 2e-17 63.3 0.1 2.2e-17 63.2 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KFM74731.1 - 0.0033 18.0 0.0 0.0034 18.0 0.0 1.0 1 0 0 1 1 1 1 ThiS family Urm1 PF09138.11 KFM74732.1 - 1.5e-10 41.3 0.0 1.6e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) BRX_N PF13713.6 KFM74732.1 - 0.043 13.6 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain CFIA_Pcf11 PF11526.8 KFM74734.1 - 1.8 9.1 0.0 1.8 9.1 0.0 4.0 2 1 1 3 3 3 0 Subunit of cleavage factor IA Pcf11 zf_UBZ PF18439.1 KFM74734.1 - 4.1 7.1 8.9 0.58 9.8 0.7 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DDE_3 PF13358.6 KFM74735.1 - 2.7e-10 40.2 0.0 6.9e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74736.1 - 5.1e-16 58.7 3.5 5.6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74736.1 - 1.2e-12 47.8 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74736.1 - 2.9e-07 30.1 0.2 7e-07 28.9 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74736.1 - 0.0027 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74736.1 - 2.4 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ABC_tran_CTD PF16326.5 KFM74737.1 - 0.0045 17.2 0.2 0.0052 17.0 0.2 1.1 1 0 0 1 1 1 1 ABC transporter C-terminal domain FlaC_arch PF05377.11 KFM74737.1 - 0.0099 16.2 0.4 0.012 16.0 0.4 1.1 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) HSBP1 PF06825.12 KFM74737.1 - 0.015 15.2 0.2 0.016 15.0 0.2 1.2 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Osmo_CC PF08946.10 KFM74737.1 - 0.046 14.0 0.8 0.066 13.5 0.8 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Prefoldin_2 PF01920.20 KFM74737.1 - 0.05 13.6 0.3 0.05 13.6 0.3 1.0 1 0 0 1 1 1 0 Prefoldin subunit MtrG PF04210.13 KFM74737.1 - 0.065 13.1 0.2 0.066 13.1 0.2 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DDE_Tnp_1_7 PF13843.6 KFM74738.1 - 1.5e-08 34.3 0.3 1.8e-08 34.1 0.3 1.1 1 0 0 1 1 1 1 Transposase IS4 RVT_1 PF00078.27 KFM74739.1 - 4.9e-12 45.8 0.0 6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFM74740.1 - 5e-05 22.9 0.0 5.6e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.18 KFM74741.1 - 3.4e-16 59.2 1.7 7.9e-16 58.1 1.7 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74741.1 - 8e-16 58.1 0.0 1.4e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM74741.1 - 3.6e-06 27.5 8.4 1.1e-05 26.0 3.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM74741.1 - 0.0013 18.6 0.6 0.059 13.3 0.1 2.4 2 0 0 2 2 2 1 MarR family HTH_3 PF01381.22 KFM74741.1 - 0.0028 17.7 0.4 0.028 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM74741.1 - 0.0034 17.3 1.8 0.03 14.3 0.1 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KFM74741.1 - 0.0096 15.7 0.7 0.22 11.4 0.1 2.8 2 0 0 2 2 2 1 Homeodomain-like domain PAX PF00292.18 KFM74741.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain HTH_28 PF13518.6 KFM74741.1 - 0.032 14.4 3.0 0.15 12.2 0.4 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KFM74741.1 - 0.1 12.2 1.3 0.76 9.4 0.0 2.4 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding CARD_2 PF16739.5 KFM74742.1 - 0.038 14.0 0.3 0.19 11.8 0.3 1.9 1 1 0 1 1 1 0 Caspase recruitment domain zinc_ribbon_11 PF11682.8 KFM74742.1 - 0.096 12.7 0.2 0.26 11.3 0.1 1.6 2 0 0 2 2 2 0 Probable zinc-ribbon THAP PF05485.12 KFM74746.1 - 1.1e-18 67.9 0.6 1.3e-18 67.7 0.6 1.1 1 0 0 1 1 1 1 THAP domain fn3 PF00041.21 KFM74747.1 - 5.9e-20 71.4 0.7 2.7e-10 40.5 0.1 2.1 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM74747.1 - 1.2e-07 32.2 1.6 0.0083 16.7 0.0 2.3 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM74747.1 - 0.0001 22.6 0.1 0.2 12.0 0.1 2.2 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFM74747.1 - 0.0054 17.1 0.0 0.3 11.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) Y_Y_Y PF07495.13 KFM74747.1 - 0.012 15.6 0.2 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 Y_Y_Y domain PhoD_N PF16655.5 KFM74747.1 - 0.046 14.3 0.1 1.5 9.4 0.0 2.2 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain HepII_C PF18675.1 KFM74747.1 - 0.13 12.3 0.1 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 Heparinase II C-terminal domain DUF3437 PF11919.8 KFM74747.1 - 0.16 11.9 0.4 5.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) fn3 PF00041.21 KFM74748.1 - 2.4e-10 40.6 0.9 3.6e-10 40.0 0.9 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Ig_3 PF13927.6 KFM74748.1 - 0.033 14.8 0.6 0.092 13.4 0.0 1.9 2 1 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 KFM74749.1 - 2.7e-50 168.4 0.0 6.5e-18 64.6 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM74749.1 - 1.5e-47 160.1 0.4 3.7e-16 59.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM74749.1 - 4.3e-35 119.9 0.4 1.4e-11 44.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM74749.1 - 1.2e-28 99.1 0.4 1.3e-09 38.0 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM74749.1 - 5.2e-20 71.7 7.6 1.2e-08 35.1 0.1 4.9 3 3 0 3 3 3 3 Immunoglobulin V-set domain fn3 PF00041.21 KFM74749.1 - 3.5e-15 56.1 0.1 5.8e-14 52.2 0.0 2.6 2 0 0 2 2 2 1 Fibronectin type III domain C2-set_2 PF08205.12 KFM74749.1 - 5.3e-14 52.1 0.3 0.00047 20.2 0.0 3.5 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM74749.1 - 6.8e-10 39.2 0.0 0.13 12.7 0.0 4.0 3 2 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFM74749.1 - 9.2e-10 38.8 0.1 0.0063 16.9 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFM74749.1 - 8.5e-08 31.7 0.0 0.011 15.3 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFM74749.1 - 2.2e-07 31.0 0.2 1.3 9.3 0.0 4.8 3 3 0 3 3 3 3 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFM74749.1 - 4e-05 23.8 0.1 0.37 11.0 0.0 2.9 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 KFM74749.1 - 0.0057 16.7 0.8 30 4.7 0.0 4.5 4 2 0 4 4 4 0 C17orf99 Ig domain SusE PF14292.6 KFM74749.1 - 0.0076 16.5 0.1 2 8.7 0.0 3.2 3 0 0 3 3 3 1 SusE outer membrane protein C2-set PF05790.15 KFM74749.1 - 0.045 13.9 0.2 5.1 7.4 0.0 3.5 2 1 0 3 3 3 0 Immunoglobulin C2-set domain Pur_ac_phosph_N PF16656.5 KFM74749.1 - 0.065 13.8 0.3 2.5 8.7 0.0 2.9 4 0 0 4 4 3 0 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 KFM74749.1 - 0.12 12.4 0.1 6.7 6.8 0.0 3.1 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain I-set PF07679.16 KFM74750.1 - 8.4e-38 128.3 0.0 2.2e-14 53.3 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM74750.1 - 2e-35 121.2 0.0 1.6e-12 47.9 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM74750.1 - 2.8e-26 91.6 0.0 1.3e-09 38.3 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM74750.1 - 9.8e-23 80.1 0.0 6.1e-08 32.7 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM74750.1 - 2.6e-12 46.9 0.2 0.016 15.3 0.0 4.4 3 2 1 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM74750.1 - 3e-07 30.4 0.0 0.47 10.5 0.0 3.4 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM74750.1 - 7.1e-07 29.4 0.0 0.00027 21.1 0.0 3.2 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM74750.1 - 5.2e-06 26.8 0.0 0.22 11.9 0.0 3.5 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM74750.1 - 6e-05 22.5 0.0 0.036 13.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFM74750.1 - 0.00058 20.2 0.0 1.2 9.5 0.1 3.4 3 1 0 3 3 3 1 Immunoglobulin C1-set domain zf-Mss51 PF13824.6 KFM74750.1 - 0.0021 18.1 0.0 1.5 9.0 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 Ig_C17orf99 PF17736.1 KFM74750.1 - 0.047 13.7 0.0 1.2 9.2 0.0 2.7 2 1 0 2 2 2 0 C17orf99 Ig domain Izumo-Ig PF16706.5 KFM74750.1 - 0.087 12.9 0.0 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 KFM74750.1 - 0.16 10.7 0.0 0.38 9.5 0.0 1.6 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E HTH_Tnp_Tc3_2 PF01498.18 KFM74751.1 - 4.3e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74751.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74751.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74751.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74751.1 - 2.1 9.0 15.6 0.12 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain BAH PF01426.18 KFM74752.1 - 1.2e-13 50.9 0.0 6.5e-13 48.6 0.0 2.2 1 1 0 1 1 1 1 BAH domain Rap_GAP PF02145.15 KFM74753.1 - 7.9e-66 221.2 0.0 1.5e-65 220.2 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP ICAP-1_inte_bdg PF10480.9 KFM74753.1 - 0.087 12.8 0.3 0.087 12.8 0.3 2.1 2 0 0 2 2 2 0 Beta-1 integrin binding protein GoLoco PF02188.17 KFM74753.1 - 0.1 12.2 3.8 0.49 10.0 3.8 2.2 1 1 0 1 1 1 0 GoLoco motif DIX PF00778.17 KFM74754.1 - 0.046 13.5 0.3 0.084 12.7 0.3 1.4 1 0 0 1 1 1 0 DIX domain BRE PF06113.12 KFM74755.1 - 1.2e-67 228.1 4.2 1.4e-67 227.8 4.2 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) UQ_con PF00179.26 KFM74755.1 - 0.071 12.8 0.3 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme DDE_3 PF13358.6 KFM74756.1 - 7.7e-08 32.2 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74757.1 - 5e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74757.1 - 1e-13 51.3 0.0 2.3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74757.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74757.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM74757.1 - 0.03 14.4 0.4 0.092 12.9 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM74757.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM74758.1 - 1.8e-16 60.1 2.2 3.9e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74758.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM74759.1 - 4.3e-16 59.0 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74759.1 - 7.5e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM74759.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM74759.1 - 0.0068 16.2 0.1 0.4 10.5 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.15 KFM74759.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM74759.1 - 0.1 12.7 0.4 0.1 12.7 0.4 2.5 3 0 0 3 3 3 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM74760.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74760.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74760.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74760.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74760.1 - 2 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain RasGEF PF00617.19 KFM74762.1 - 1.3e-52 178.6 2.6 6.6e-52 176.3 2.6 2.2 1 1 0 1 1 1 1 RasGEF domain PH PF00169.29 KFM74762.1 - 7e-12 45.8 0.1 1.4e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM74762.1 - 0.022 15.1 0.0 0.085 13.3 0.0 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain EMC3_TMCO1 PF01956.16 KFM74763.1 - 2.3e-41 141.3 0.3 2.9e-41 141.0 0.3 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like XhlA PF10779.9 KFM74763.1 - 0.0039 17.4 0.4 0.0067 16.6 0.4 1.5 1 0 0 1 1 1 1 Haemolysin XhlA Vpu PF00558.19 KFM74763.1 - 0.022 14.5 0.7 0.043 13.6 0.7 1.5 1 1 0 1 1 1 0 Vpu protein DivIC PF04977.15 KFM74763.1 - 0.028 14.2 5.9 0.3 10.9 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Nucleoside_tran PF01733.18 KFM74763.1 - 0.033 13.6 0.7 0.057 12.8 0.2 1.5 1 1 0 2 2 2 0 Nucleoside transporter ATG19_autophagy PF12744.7 KFM74763.1 - 0.048 12.8 1.1 0.064 12.5 1.1 1.1 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding TRAM1 PF08390.11 KFM74763.1 - 0.058 13.1 0.1 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 TRAM1-like protein CbiC PF02570.15 KFM74763.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Precorrin-8X methylmutase LapA_dom PF06305.11 KFM74763.1 - 5.1 7.0 12.8 1.4 8.8 0.1 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Alg14 PF08660.11 KFM74764.1 - 2.6 7.9 4.2 8 6.4 4.2 1.8 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Presenilin PF01080.17 KFM74765.1 - 7.3e-167 555.1 3.2 1.1e-166 554.6 3.2 1.3 1 0 0 1 1 1 1 Presenilin GlgX_C PF18390.1 KFM74765.1 - 0.17 11.7 0.5 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme C-terminal domain ATP-synt_S1 PF05827.12 KFM74765.1 - 1.1 9.0 4.6 9.5 6.0 1.1 2.6 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) WD40 PF00400.32 KFM74766.1 - 1.3e-06 29.0 7.1 3.3e-05 24.6 0.3 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFM74766.1 - 0.0016 17.5 0.1 0.0032 16.5 0.0 1.4 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KFM74766.1 - 0.015 15.6 0.1 0.85 10.0 0.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM74766.1 - 0.051 12.9 0.0 7.8 5.7 0.0 2.0 1 1 1 2 2 2 0 WD40-like domain DUF4371 PF14291.6 KFM74768.1 - 3.5e-10 39.9 0.1 1.2e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM74768.1 - 0.00021 20.8 0.7 0.00021 20.8 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger C2H2-type SNF PF00209.18 KFM74769.1 - 4.5e-55 187.3 43.6 5.7e-55 187.0 43.6 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Tmemb_9 PF05434.11 KFM74769.1 - 0.085 12.8 0.2 0.085 12.8 0.2 2.5 2 0 0 2 2 2 0 TMEM9 DDE_1 PF03184.19 KFM74771.1 - 1.6e-17 63.7 0.1 2.6e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM74771.1 - 4.6e-12 45.8 0.4 1e-11 44.7 0.4 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM74771.1 - 0.0034 17.1 0.0 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3372 PF11852.8 KFM74771.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) CAP PF00188.26 KFM74772.1 - 7.6e-22 78.5 0.4 1.7e-21 77.4 0.4 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KFM74773.1 - 2.3e-08 34.9 0.1 3.7e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DDE_3 PF13358.6 KFM74774.1 - 0.0018 18.0 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3375 PF11855.8 KFM74775.1 - 0.022 13.7 0.4 0.029 13.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF3545 PF12065.8 KFM74775.1 - 0.15 12.1 2.6 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) SPATA3 PF15662.5 KFM74775.1 - 0.27 11.9 5.5 0.31 11.7 5.5 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family GCN5L1 PF06320.13 KFM74776.1 - 8.4e-47 158.0 8.8 9.4e-47 157.9 8.8 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Trehalose_recp PF06151.13 KFM74776.1 - 0.0015 17.2 0.0 0.0019 16.9 0.0 1.0 1 0 0 1 1 1 1 Trehalose receptor Sec2p PF06428.11 KFM74776.1 - 0.035 14.1 6.0 0.058 13.4 5.5 1.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Prominin PF05478.11 KFM74776.1 - 0.53 8.2 6.1 0.81 7.6 5.5 1.5 1 1 1 2 2 2 0 Prominin Syntaxin-18_N PF10496.9 KFM74776.1 - 0.67 10.2 4.7 7.7 6.8 4.7 2.1 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus LMBR1 PF04791.16 KFM74776.1 - 0.81 8.5 2.3 0.89 8.4 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RAG1 PF12940.7 KFM74778.1 - 0.094 10.8 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase FUSC PF04632.12 KFM74779.1 - 2.6 6.5 5.9 6.7 5.1 5.9 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family HTH_Tnp_Tc3_2 PF01498.18 KFM74780.1 - 8.5e-08 32.3 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM74780.1 - 0.029 15.0 0.0 0.058 14.0 0.0 1.6 1 1 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 KFM74780.1 - 0.039 13.7 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain PDZ PF00595.24 KFM74781.1 - 4.1e-42 142.4 5.2 4.7e-15 55.7 0.5 3.6 3 0 0 3 3 3 3 PDZ domain ZU5 PF00791.20 KFM74781.1 - 3.4e-37 126.7 0.0 1.1e-36 125.1 0.0 1.9 1 0 0 1 1 1 1 ZU5 domain PDZ_6 PF17820.1 KFM74781.1 - 2e-22 78.8 3.4 7.1e-08 32.2 0.2 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFM74781.1 - 2.3e-12 47.0 3.8 0.0024 18.1 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 KFM74781.1 - 2.9e-11 43.4 0.0 3.7e-10 39.8 0.0 2.4 1 1 1 2 2 2 1 Guanylate kinase SH3_2 PF07653.17 KFM74781.1 - 1.9e-10 40.2 0.1 2.1e-09 36.9 0.1 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFM74781.1 - 0.0022 17.6 0.1 0.0092 15.6 0.0 2.2 2 0 0 2 2 2 1 SH3 domain C2 PF00168.30 KFM74782.1 - 3.6e-22 78.6 0.0 4.7e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 C2 domain Bacillus_HBL PF05791.11 KFM74782.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Ost5 PF05251.12 KFM74783.1 - 4e-29 100.7 8.3 4.6e-29 100.5 8.3 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 CbtB PF09489.10 KFM74783.1 - 0.98 9.6 6.6 5 7.3 1.5 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) SSPI PF14098.6 KFM74783.1 - 6.3 7.0 6.0 34 4.7 2.9 2.1 2 0 0 2 2 2 0 Small, acid-soluble spore protein I Ribosomal_S10 PF00338.22 KFM74784.1 - 2.8e-24 85.2 0.1 3.3e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ELO PF01151.18 KFM74785.1 - 4.6e-62 209.8 19.0 5.8e-62 209.5 19.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family TssO PF17561.2 KFM74785.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.5 3 0 0 3 3 3 0 Type VI secretion system, TssO DUF1736 PF08409.11 KFM74788.1 - 2.6e-30 104.2 4.3 2.6e-30 104.2 4.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 KFM74789.1 - 1.7e-11 43.3 0.3 8.8e-05 22.3 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM74789.1 - 3.6e-11 42.4 0.1 1.6e-05 24.5 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM74789.1 - 2.1e-09 37.6 3.5 0.0024 18.1 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM74789.1 - 4e-09 36.6 1.0 4.9e-05 23.8 0.1 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM74789.1 - 8.5e-09 34.9 0.1 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM74789.1 - 6.4e-08 32.1 0.5 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM74789.1 - 1.5e-07 31.1 4.6 0.0048 16.7 0.4 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM74789.1 - 2e-07 31.5 0.1 3.4e-07 30.8 0.1 1.4 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM74789.1 - 4.6e-07 29.4 0.2 1.7e-06 27.6 0.0 2.0 2 1 1 3 3 3 1 TPR repeat TPR_19 PF14559.6 KFM74789.1 - 4.5e-06 27.1 0.2 1e-05 26.0 0.1 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM74789.1 - 0.00026 21.2 0.0 0.027 14.8 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM74789.1 - 0.0095 16.1 0.8 0.027 14.6 0.4 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 KFM74789.1 - 0.024 13.6 0.0 0.027 13.4 0.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KFM74789.1 - 0.059 14.0 0.1 12 6.8 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM74789.1 - 0.13 12.5 0.4 1.3 9.2 0.3 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-H2C2_2 PF13465.6 KFM74790.1 - 6.7e-06 26.3 4.1 9.3e-06 25.9 4.1 1.3 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74790.1 - 0.14 12.7 5.9 1.8 9.2 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 KFM74790.1 - 0.19 12.2 5.3 0.66 10.5 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type RNase_H PF00075.24 KFM74791.1 - 0.00084 19.5 0.0 0.0017 18.6 0.0 1.4 1 1 0 1 1 1 1 RNase H zf-H2C2_2 PF13465.6 KFM74792.1 - 1.2e-09 38.1 12.9 4.2e-08 33.2 2.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74792.1 - 1.2e-07 31.8 13.5 8.8e-05 22.8 2.2 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM74792.1 - 2.7e-07 30.7 5.5 0.0064 16.8 1.5 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFM74792.1 - 7.1e-06 26.4 9.8 0.0063 17.3 2.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM74792.1 - 2.8e-05 24.4 9.3 0.011 16.2 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM74792.1 - 0.0051 17.1 3.9 0.009 16.3 3.9 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-Sec23_Sec24 PF04810.15 KFM74792.1 - 0.099 12.7 3.4 9.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 KFM74792.1 - 0.1 12.9 4.9 2.2 8.7 0.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.15 KFM74792.1 - 0.12 12.3 3.8 1.5 8.8 0.5 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.16 KFM74792.1 - 2.1 8.6 11.3 4.5 7.5 1.3 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2H2_6 PF13912.6 KFM74792.1 - 2.8 8.0 11.9 2.1 8.4 1.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KFM74792.1 - 3.4 7.8 9.7 0.95 9.5 0.5 2.5 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_2 PF13465.6 KFM74793.1 - 7.6e-12 45.1 17.1 2.4e-09 37.2 5.3 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74793.1 - 7.5e-08 32.4 16.7 7.1e-05 23.1 3.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74793.1 - 0.0011 19.7 18.7 0.023 15.5 2.3 2.4 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74793.1 - 0.0034 17.6 1.4 0.0034 17.6 1.4 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM74793.1 - 0.0044 17.3 9.5 0.0074 16.6 0.6 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM74793.1 - 0.011 15.5 2.7 0.011 15.5 2.7 3.2 4 0 0 4 4 3 0 C2H2-type zinc-finger domain PyrI_C PF02748.15 KFM74793.1 - 0.015 15.2 8.9 0.13 12.2 0.9 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 KFM74793.1 - 0.039 14.0 2.2 0.039 14.0 2.2 2.3 1 1 1 2 2 2 0 BED zinc finger zf-TRAF PF02176.18 KFM74793.1 - 0.048 14.3 7.6 0.055 14.2 7.6 1.1 1 0 0 1 1 1 0 TRAF-type zinc finger Ribosomal_L22e PF01776.17 KFM74793.1 - 0.058 13.8 0.1 0.06 13.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal L22e protein family zf-C2HE PF16278.5 KFM74793.1 - 0.079 13.4 2.4 0.079 13.4 2.4 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 KFM74793.1 - 0.13 12.6 7.2 0.13 12.6 7.2 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon DUF2225 PF09986.9 KFM74793.1 - 0.26 11.0 4.7 0.4 10.4 4.7 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.12 KFM74793.1 - 0.53 10.6 11.2 1.9 8.8 10.9 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFM74793.1 - 0.8 9.5 9.0 0.79 9.5 1.5 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KFM74793.1 - 4.2 7.9 20.3 0.24 11.9 1.1 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HTH_Tnp_Tc3_2 PF01498.18 KFM74795.1 - 2.4e-13 50.1 0.3 3.5e-13 49.6 0.3 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM74795.1 - 0.044 13.6 0.4 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain RCC1 PF00415.18 KFM74797.1 - 2.4e-51 172.2 20.2 5.8e-16 58.9 0.3 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM74797.1 - 2.3e-41 138.8 23.4 5.2e-09 35.7 0.1 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Kelch_1 PF01344.25 KFM74797.1 - 0.0062 16.1 3.5 0.81 9.3 0.4 2.7 2 0 0 2 2 2 2 Kelch motif PQQ_3 PF13570.6 KFM74797.1 - 0.009 16.5 7.1 9.1 6.9 0.1 4.5 3 1 0 3 3 3 1 PQQ-like domain Kelch_6 PF13964.6 KFM74797.1 - 0.011 16.0 5.9 2.3 8.7 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Mcl1_mid PF12341.8 KFM74797.1 - 0.1 11.9 0.1 1.5 8.1 0.0 2.6 2 1 1 3 3 3 0 Minichromosome loss protein, Mcl1, middle region Peptidase_C25_C PF03785.14 KFM74797.1 - 0.14 12.1 0.1 3.1 7.7 0.0 3.1 5 0 0 5 5 5 0 Peptidase family C25, C terminal ig-like domain Kelch_4 PF13418.6 KFM74797.1 - 0.46 10.5 12.4 30 4.7 0.0 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain UPA_2 PF17809.1 KFM74798.1 - 0.078 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 UPA domain GOLD_2 PF13897.6 KFM74798.1 - 0.78 10.2 10.9 0.088 13.3 1.7 2.6 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking DUF1358 PF07096.11 KFM74801.1 - 3.9e-38 130.0 0.1 5.2e-38 129.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) Phage_holin_3_6 PF07332.11 KFM74801.1 - 0.021 14.9 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HTH_48 PF17906.1 KFM74802.1 - 8.1e-05 22.7 0.1 0.00017 21.6 0.1 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF4817 PF16087.5 KFM74802.1 - 0.012 15.4 0.0 0.04 13.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) HTH_24 PF13412.6 KFM74802.1 - 0.026 14.1 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KFM74802.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CheC PF04509.12 KFM74802.1 - 0.16 11.9 0.1 0.41 10.6 0.0 1.7 2 0 0 2 2 2 0 CheC-like family Laminin_I PF06008.14 KFM74803.1 - 0.032 13.9 0.5 0.039 13.7 0.5 1.1 1 0 0 1 1 1 0 Laminin Domain I Sulfotransfer_4 PF17784.1 KFM74803.1 - 0.038 13.8 0.1 0.039 13.8 0.1 1.0 1 0 0 1 1 1 0 Sulfotransferase domain AvrPto PF11592.8 KFM74803.1 - 0.069 13.2 0.2 0.075 13.1 0.2 1.1 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto DUF883 PF05957.13 KFM74803.1 - 0.12 13.0 0.2 0.18 12.4 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) BLOC1_2 PF10046.9 KFM74804.1 - 0.0088 16.3 2.6 0.014 15.7 0.5 2.0 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 KFM74804.1 - 0.034 14.5 5.4 0.073 13.5 0.7 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF4988 PF16378.5 KFM74804.1 - 0.041 13.5 1.1 0.48 10.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function Surfac_D-trimer PF09006.11 KFM74804.1 - 0.042 13.7 0.2 0.071 13.0 0.2 1.4 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation FlxA PF14282.6 KFM74804.1 - 0.046 13.7 3.9 0.046 13.7 3.9 1.6 2 0 0 2 2 2 0 FlxA-like protein Phage_GP20 PF06810.11 KFM74804.1 - 0.052 13.4 0.9 0.058 13.2 0.1 1.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 XhlA PF10779.9 KFM74804.1 - 0.057 13.6 0.8 0.1 12.8 0.8 1.4 1 0 0 1 1 1 0 Haemolysin XhlA DUF2730 PF10805.8 KFM74804.1 - 0.066 13.3 0.9 0.11 12.6 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) bZIP_2 PF07716.15 KFM74804.1 - 0.079 13.0 2.5 0.23 11.6 2.5 1.8 1 0 0 1 1 1 0 Basic region leucine zipper Syntaxin-6_N PF09177.11 KFM74804.1 - 0.081 13.5 1.1 0.17 12.4 0.6 1.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.20 KFM74804.1 - 0.11 12.4 4.2 0.081 12.9 2.5 1.6 2 0 0 2 2 2 0 Prefoldin subunit Fzo_mitofusin PF04799.13 KFM74804.1 - 0.15 11.6 2.5 0.11 12.0 1.0 1.5 2 0 0 2 2 2 0 fzo-like conserved region DivIC PF04977.15 KFM74804.1 - 0.96 9.3 5.9 0.46 10.3 2.9 2.0 2 1 1 3 3 3 0 Septum formation initiator HTH_Tnp_Tc3_2 PF01498.18 KFM74805.1 - 1.3e-14 54.2 1.5 2.8e-14 53.1 1.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM74805.1 - 3.8e-06 27.4 2.3 1.2e-05 25.8 2.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain FUR PF01475.19 KFM74805.1 - 0.1 12.7 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Ferric uptake regulator family Retrotran_gag_2 PF14223.6 KFM74806.1 - 5.6e-12 45.5 0.1 2e-11 43.7 0.1 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KFM74806.1 - 3.4e-07 30.0 0.2 1.5e-06 27.9 0.2 2.2 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 KFM74806.1 - 0.086 13.0 3.2 0.18 11.9 3.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Baculo_gp41 PF04700.12 KFM74806.1 - 0.094 12.5 3.4 1.7 8.4 0.2 2.3 2 0 0 2 2 2 0 Structural glycoprotein p40/gp41 conserved region Copper-fist PF00649.18 KFM74806.1 - 0.39 10.3 3.4 0.64 9.6 1.0 2.4 2 0 0 2 2 2 0 Copper fist DNA binding domain Ribosomal_L44 PF00935.19 KFM74806.1 - 0.41 11.1 3.3 1.5 9.3 3.3 2.0 1 1 0 1 1 1 0 Ribosomal protein L44 zf-CCHC_2 PF13696.6 KFM74806.1 - 2.5 8.0 5.9 1.4 8.8 2.4 2.3 3 0 0 3 3 3 0 Zinc knuckle AT_hook PF02178.19 KFM74806.1 - 5 7.3 7.7 2.6 8.2 2.2 2.7 2 0 0 2 2 2 0 AT hook motif Joubert PF15392.6 KFM74806.1 - 5.5 6.6 8.2 0.52 10.0 0.1 2.4 3 0 0 3 3 3 0 Joubert syndrome-associated SH3_1 PF00018.28 KFM74807.1 - 4.9e-08 32.5 0.0 6.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM74807.1 - 0.00018 21.3 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM74807.1 - 0.0026 17.4 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SspH PF08141.12 KFM74808.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Small acid-soluble spore protein H family LSM PF01423.22 KFM74809.1 - 2e-10 40.2 0.0 2.6e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.8 KFM74809.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) RT_RNaseH_2 PF17919.1 KFM74810.1 - 2.5e-12 46.7 0.0 5.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM74810.1 - 0.014 15.7 0.0 0.048 13.9 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Vps52 PF04129.12 KFM74811.1 - 1.7e-72 244.8 3.4 1.7e-72 244.8 3.4 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family Vps52 PF04129.12 KFM74812.1 - 9.5e-77 258.9 13.8 1e-76 258.7 13.8 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KFM74812.1 - 0.00048 18.7 4.0 0.00048 18.7 4.0 1.6 1 1 0 2 2 2 1 Exocyst complex component Sec3 Cauli_DNA-bind PF03310.13 KFM74812.1 - 0.2 11.7 2.0 0.14 12.3 0.5 1.5 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Cas9_Topo PF17894.1 KFM74812.1 - 0.21 11.7 1.9 0.27 11.3 0.1 2.1 2 1 1 3 3 3 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 RVT_2 PF07727.14 KFM74814.1 - 2.9e-66 223.5 1.8 4.6e-66 222.9 1.8 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.19 KFM74814.1 - 3.9e-35 121.1 0.1 1.2e-34 119.5 0.1 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 KFM74814.1 - 6.9e-24 84.3 0.0 1.4e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 KFM74814.1 - 4.4e-23 81.5 0.0 1e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KFM74814.1 - 1.5e-13 50.4 0.2 8e-13 48.1 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 KFM74814.1 - 0.0019 17.9 0.0 0.0063 16.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 KFM74814.1 - 0.02 14.9 1.3 0.05 13.7 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Sigma70_r4 PF04545.16 KFM74814.1 - 0.029 13.9 0.3 0.072 12.6 0.3 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 RVT_1 PF00078.27 KFM74814.1 - 0.055 13.0 0.1 0.2 11.1 0.1 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M13_N PF05649.13 KFM74815.1 - 6.8e-80 269.6 0.0 9.3e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM74815.1 - 6e-40 137.0 0.0 1e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Connexin PF00029.19 KFM74815.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Connexin DUF3671 PF12420.8 KFM74815.1 - 0.03 14.4 0.2 0.11 12.6 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function Ninjurin PF04923.12 KFM74815.1 - 0.079 12.9 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Ninjurin Baculo_11_kDa PF06143.11 KFM74815.1 - 0.34 10.5 1.9 0.86 9.2 1.9 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family HTH_48 PF17906.1 KFM74816.1 - 8.2e-07 29.0 0.0 2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_24 PF13412.6 KFM74816.1 - 0.058 13.0 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding zf-H2C2_2 PF13465.6 KFM74818.1 - 5.5e-115 371.2 108.4 2.6e-09 37.1 0.1 16.1 16 0 0 16 16 16 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74818.1 - 7.6e-69 224.5 142.1 4e-06 27.0 2.5 15.1 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74818.1 - 1.7e-49 162.2 126.3 0.00016 22.2 1.7 15.2 15 0 0 15 15 15 15 C2H2-type zinc finger zf-met PF12874.7 KFM74818.1 - 5.3e-42 141.0 124.6 3.8e-05 23.9 2.0 15.3 15 0 0 15 15 15 13 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM74818.1 - 1.9e-29 101.3 83.1 0.0013 18.9 0.7 15.1 15 0 0 15 15 15 11 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM74818.1 - 2.4e-21 75.5 58.2 0.0084 16.1 1.7 14.4 5 4 10 15 15 15 9 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 KFM74818.1 - 8.1e-16 57.6 96.5 0.00013 21.8 0.9 15.6 15 0 0 15 15 15 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM74818.1 - 1.3e-14 53.6 99.7 0.075 12.8 0.2 15.7 15 0 0 15 15 15 9 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 KFM74818.1 - 3.7e-10 39.5 80.2 0.2 11.5 0.2 14.8 3 2 12 15 15 15 5 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM74818.1 - 8.1e-10 38.4 47.5 0.91 9.5 0.3 12.2 12 1 0 12 12 12 5 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM74818.1 - 2.1e-09 37.4 63.8 8.1 6.7 0.3 15.2 15 0 0 15 15 15 0 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM74818.1 - 5.7e-06 26.4 65.5 0.14 12.2 5.1 7.0 1 1 6 7 7 7 4 Putative ribonucleoprotein zinc-finger pf C4 type BolA PF01722.18 KFM74818.1 - 2.7e-05 24.4 40.4 1.4 9.2 0.2 9.8 1 1 4 8 8 8 4 BolA-like protein DUF2256 PF10013.9 KFM74818.1 - 2.8e-05 24.1 54.0 15 5.8 0.1 14.7 15 0 0 15 15 15 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFM74818.1 - 4.3e-05 23.0 76.1 0.3 10.7 0.3 14.4 7 4 8 15 15 15 5 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFM74818.1 - 0.0018 19.0 66.5 1.5 9.6 1.4 7.9 1 1 7 8 8 8 5 zinc-ribbon family NusB PF01029.18 KFM74818.1 - 0.0043 17.3 0.1 9.7 6.4 0.0 4.7 2 1 5 7 7 7 0 NusB family GAGA PF09237.11 KFM74818.1 - 0.013 15.3 33.6 1.5 8.7 0.0 9.9 2 2 11 13 13 13 0 GAGA factor Zf_RING PF16744.5 KFM74818.1 - 0.046 13.8 74.9 3.4 7.8 3.8 14.2 1 1 10 12 12 12 0 KIAA1045 RING finger Yop-YscD_ppl PF16693.5 KFM74818.1 - 0.06 12.8 0.0 7.7 5.9 0.0 3.5 2 1 3 5 5 5 0 Inner membrane component of T3SS, periplasmic domain zf-C2H2_11 PF16622.5 KFM74818.1 - 0.13 12.0 0.3 0.13 12.0 0.3 13.5 15 0 0 15 15 14 0 zinc-finger C2H2-type CBP_BcsQ PF06564.12 KFM74818.1 - 0.44 10.0 4.6 8.7 5.7 0.3 3.6 2 1 2 4 4 4 0 Cellulose biosynthesis protein BcsQ LZ3wCH PF18517.1 KFM74818.1 - 0.64 10.2 5.1 22 5.2 0.0 5.2 9 0 0 9 9 4 0 Leucine zipper with capping helix domain NAD_kinase PF01513.21 KFM74818.1 - 1.2 8.2 5.5 23 4.0 0.1 4.0 1 1 1 2 2 2 0 ATP-NAD kinase Zn_ribbon_SprT PF17283.2 KFM74818.1 - 6.4 6.8 48.5 4.7 7.2 1.4 10.7 8 4 2 10 10 10 0 SprT-like zinc ribbon domain DUF5330 PF17264.2 KFM74818.1 - 6.6 6.8 26.9 64 3.7 0.0 9.4 10 0 0 10 10 10 0 Family of unknown function (DUF5330) BTB_3 PF16017.5 KFM74820.1 - 6.6e-51 170.8 0.0 1.1e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KFM74820.1 - 0.15 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 KFM74820.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Wzy_C PF04932.15 KFM74821.1 - 0.01 15.5 0.9 0.012 15.3 0.9 1.1 1 0 0 1 1 1 1 O-Antigen ligase BCCT PF02028.17 KFM74821.1 - 1 7.8 6.9 0.43 9.0 4.4 1.5 1 1 1 2 2 2 0 BCCT, betaine/carnitine/choline family transporter VWC PF00093.18 KFM74822.1 - 3e-14 53.0 43.9 2.5e-09 37.3 17.9 3.9 3 1 0 3 3 3 2 von Willebrand factor type C domain EGF_CA PF07645.15 KFM74822.1 - 8.9e-13 48.2 19.4 1.2e-08 35.0 9.6 5.4 4 2 0 4 4 4 2 Calcium-binding EGF domain EGF_3 PF12947.7 KFM74822.1 - 3.4e-07 30.3 15.4 8.9e-05 22.6 0.8 5.2 4 2 0 4 4 4 2 EGF domain cEGF PF12662.7 KFM74822.1 - 1.7e-06 27.8 1.3 1.7e-06 27.8 1.3 5.1 4 0 0 4 4 4 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFM74822.1 - 0.022 15.1 3.4 0.022 15.1 3.4 5.7 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site VWC PF00093.18 KFM74823.1 - 5.3e-17 61.9 34.2 7.6e-12 45.4 12.0 4.5 5 0 0 5 5 4 2 von Willebrand factor type C domain EGF_CA PF07645.15 KFM74823.1 - 3.3e-09 36.8 23.1 1.3e-07 31.7 5.0 4.7 5 0 0 5 5 3 2 Calcium-binding EGF domain Laminin_G_3 PF13385.6 KFM74823.1 - 3.3e-09 37.1 0.2 6.4e-09 36.1 0.0 1.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF_3 PF12947.7 KFM74823.1 - 5.6e-08 32.9 12.5 5.6e-08 32.9 12.5 4.8 5 0 0 5 5 4 2 EGF domain cEGF PF12662.7 KFM74823.1 - 1e-06 28.5 2.8 1e-06 28.5 2.8 5.3 6 0 0 6 6 6 2 Complement Clr-like EGF-like hEGF PF12661.7 KFM74823.1 - 4.9e-06 27.0 12.3 0.0001 22.8 2.7 4.9 6 0 0 6 6 3 2 Human growth factor-like EGF EGF PF00008.27 KFM74823.1 - 2.3e-05 24.6 19.6 6e-05 23.3 8.0 5.0 5 1 0 5 5 4 2 EGF-like domain Laminin_G_2 PF02210.24 KFM74823.1 - 3.8e-05 24.3 0.2 6.5e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 Laminin G domain EGF_MSP1_1 PF12946.7 KFM74823.1 - 0.00014 21.8 23.2 0.0082 16.2 7.5 3.7 3 0 0 3 3 3 2 MSP1 EGF domain 1 CFC PF09443.10 KFM74823.1 - 0.00038 20.2 19.1 0.0041 16.9 2.8 3.8 3 0 0 3 3 3 2 Cripto_Frl-1_Cryptic (CFC) TILa PF12714.7 KFM74823.1 - 0.0006 19.7 5.6 0.0006 19.7 5.6 5.5 2 2 2 5 5 4 1 TILa domain Laminin_G_1 PF00054.23 KFM74823.1 - 0.08 13.2 0.1 0.17 12.1 0.1 1.4 1 1 0 1 1 1 0 Laminin G domain TMF_DNA_bd PF12329.8 KFM74823.1 - 0.087 12.8 0.4 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DASH_Dad3 PF08656.10 KFM74823.1 - 0.13 12.4 0.5 4.8 7.3 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Cep57_CLD_2 PF14197.6 KFM74823.1 - 0.27 11.3 1.3 0.53 10.4 1.3 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Pyr_redox_2 PF07992.14 KFM74824.1 - 1e-08 34.8 0.0 5e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM74824.1 - 1.7e-08 34.1 0.0 3.5e-07 29.8 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM74824.1 - 0.08 12.1 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-HC5HC2H PF13771.6 KFM74826.1 - 6.6e-12 45.5 6.1 1e-11 44.9 6.1 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFM74826.1 - 1.2e-09 38.3 6.0 1.6e-09 37.9 6.0 1.2 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 KFM74826.1 - 0.016 15.2 3.9 0.029 14.4 3.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_12 PF18658.1 KFM74828.1 - 0.0096 15.5 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger C2H2-type DNA_pol_D_N PF18018.1 KFM74828.1 - 0.12 12.4 0.0 0.14 12.3 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Nnf1 PF03980.14 KFM74829.1 - 3.3e-14 53.2 2.8 5.7e-14 52.4 2.8 1.4 1 0 0 1 1 1 1 Nnf1 HCNGP PF07818.13 KFM74829.1 - 0.0029 18.2 0.2 0.0054 17.3 0.2 1.6 1 0 0 1 1 1 1 HCNGP-like protein Baculo_p24 PF05073.12 KFM74829.1 - 0.036 13.9 3.1 0.054 13.3 2.5 1.6 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF4211 PF13926.6 KFM74829.1 - 0.058 13.4 1.2 0.15 12.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) YojJ PF10372.9 KFM74829.1 - 0.24 11.5 6.9 0.16 12.1 0.7 2.8 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM74831.1 - 4.7e-16 58.8 3.5 6.1e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74831.1 - 2.2e-12 46.9 0.0 3.8e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74831.1 - 2.3e-07 30.5 1.2 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74831.1 - 0.0029 17.4 0.6 0.008 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74831.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain F-box-like PF12937.7 KFM74832.1 - 3.7e-11 42.7 2.1 3.9e-11 42.7 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFM74832.1 - 1.2e-08 34.6 1.5 1.2e-08 34.6 1.5 2.2 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 KFM74832.1 - 0.023 14.3 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 F-box Wound_ind PF08186.11 KFM74832.1 - 0.061 13.8 0.3 0.13 12.7 0.3 1.5 1 0 0 1 1 1 0 Wound-inducible basic protein family PAW PF04721.17 KFM74833.1 - 6.5e-63 212.1 1.0 1.1e-62 211.4 1.0 1.3 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Rad4 PF03835.15 KFM74833.1 - 2.8e-09 36.8 0.7 2.8e-09 36.8 0.7 1.6 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KFM74833.1 - 0.7 10.4 2.7 1.6 9.2 0.7 2.5 3 0 0 3 3 3 0 Transglutaminase-like superfamily MoCF_biosynth PF00994.24 KFM74835.1 - 1e-27 96.6 0.0 2e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 KFM74835.1 - 1e-27 97.3 0.0 2.3e-18 66.9 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF1858 PF08984.11 KFM74835.1 - 0.051 13.8 0.0 5 7.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) Tropomyosin PF00261.20 KFM74836.1 - 1.4e-85 286.5 72.0 7.6e-80 267.7 54.2 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFM74836.1 - 1.5e-31 109.5 68.8 5.6e-29 101.1 35.0 3.7 1 1 3 4 4 4 4 Tropomyosin like Laminin_II PF06009.12 KFM74836.1 - 0.00011 22.2 34.8 0.0013 18.8 9.1 3.8 1 1 3 4 4 4 3 Laminin Domain II ATG16 PF08614.11 KFM74836.1 - 0.0091 16.2 60.5 0.07 13.4 24.2 3.1 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) DUF745 PF05335.13 KFM74836.1 - 0.011 15.5 24.2 0.011 15.5 24.2 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF745) COG5 PF10392.9 KFM74836.1 - 0.011 15.9 10.6 0.011 15.9 10.6 2.9 1 1 1 3 3 3 0 Golgi transport complex subunit 5 Trimer_CC PF08954.11 KFM74836.1 - 0.012 15.2 0.6 0.012 15.2 0.6 5.5 5 1 1 6 6 6 0 Trimerisation motif CLZ PF16526.5 KFM74836.1 - 0.025 14.9 9.5 0.025 14.9 9.5 5.5 1 1 4 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fez1 PF06818.15 KFM74836.1 - 0.057 13.9 48.9 1.9 8.9 23.1 2.8 1 1 1 2 2 2 0 Fez1 BST2 PF16716.5 KFM74836.1 - 0.24 12.0 40.6 0.34 11.5 5.1 4.8 1 1 4 5 5 5 0 Bone marrow stromal antigen 2 DUF2007 PF09413.10 KFM74836.1 - 0.52 10.5 8.4 0.98 9.6 0.1 4.2 3 2 1 4 4 4 0 Putative prokaryotic signal transducing protein SIM_C PF06621.12 KFM74836.1 - 0.78 9.7 3.4 15 5.5 1.2 2.3 2 1 0 2 2 2 0 Single-minded protein C-terminus Fib_alpha PF08702.10 KFM74836.1 - 0.89 9.7 34.5 0.65 10.2 6.4 3.8 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFM74836.1 - 0.95 9.5 32.6 1.5 8.9 1.4 4.2 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Uds1 PF15456.6 KFM74836.1 - 1.2 9.3 44.3 0.72 10.0 3.6 3.9 1 1 3 4 4 4 0 Up-regulated During Septation DUF16 PF01519.16 KFM74836.1 - 1.7 9.2 38.1 4.2 7.9 7.3 4.3 1 1 2 3 3 2 0 Protein of unknown function DUF16 HrpB7 PF09486.10 KFM74836.1 - 1.7 9.0 54.8 2.4 8.6 10.4 4.4 1 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF1794 PF08768.11 KFM74836.1 - 1.8 8.5 7.0 8.4 6.3 0.3 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1794) XhlA PF10779.9 KFM74836.1 - 2 8.7 39.9 1.2 9.4 0.8 5.8 2 2 6 8 8 8 0 Haemolysin XhlA HemX PF04375.14 KFM74836.1 - 2.1 7.6 42.7 2.2 7.5 1.0 3.0 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF948 PF06103.11 KFM74836.1 - 2.2 8.6 12.2 4.1 7.7 0.7 3.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Lebercilin PF15619.6 KFM74836.1 - 3.8 7.1 63.1 0.54 9.9 22.4 3.3 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF4200 PF13863.6 KFM74836.1 - 4.3 7.8 67.9 6.3 7.2 13.0 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) FH2 PF02181.23 KFM74836.1 - 4.9 6.2 27.4 0.37 9.8 9.0 2.9 1 1 2 3 3 3 0 Formin Homology 2 Domain AAA_13 PF13166.6 KFM74836.1 - 5.7 5.4 45.7 2.3 6.7 34.0 2.2 1 1 1 2 2 2 0 AAA domain DUF1796 PF08795.10 KFM74836.1 - 6.4 6.7 12.7 0.67 9.9 1.1 3.5 2 2 2 4 4 4 0 Putative papain-like cysteine peptidase (DUF1796) DUF3450 PF11932.8 KFM74836.1 - 8.5 5.6 48.1 0.22 10.8 13.1 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) SNARE_assoc PF09335.11 KFM74837.1 - 1.1e-19 71.1 11.4 1.1e-19 71.1 7.5 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein zf-C2H2 PF00096.26 KFM74838.1 - 1.9e-15 56.4 52.4 0.0026 18.1 4.3 7.9 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74838.1 - 4.1e-10 39.6 50.3 0.031 15.1 4.4 7.8 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM74838.1 - 1.6e-09 37.8 36.5 9.4e-05 22.7 0.5 7.2 7 0 0 7 7 7 3 Zinc-finger double domain zf-met PF12874.7 KFM74838.1 - 9.9e-09 35.3 29.5 0.027 14.9 0.3 7.2 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM74838.1 - 4e-07 30.2 31.2 0.005 17.1 3.9 4.6 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.18 KFM74838.1 - 0.0088 16.7 2.0 0.0088 16.7 2.0 4.1 5 0 0 5 5 5 1 TRAF-type zinc finger Trm112p PF03966.16 KFM74838.1 - 0.047 14.3 0.2 1.6 9.4 0.0 3.1 2 0 0 2 2 2 0 Trm112p-like protein zf-C2H2_6 PF13912.6 KFM74838.1 - 0.058 13.4 24.8 0.083 12.9 0.0 5.4 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM74838.1 - 0.77 10.1 24.4 0.21 11.9 0.5 5.7 2 2 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM74838.1 - 6.7 6.4 14.1 3.6 7.3 0.2 5.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KFM74839.1 - 6.1e-78 254.0 67.8 3.5e-08 33.5 0.4 11.7 12 0 0 12 12 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74839.1 - 1.2e-48 161.0 87.2 6.6e-06 26.3 0.7 11.2 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74839.1 - 1.1e-38 128.6 84.3 6.3e-05 23.5 0.8 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM74839.1 - 1.4e-22 79.3 67.6 0.0081 16.5 0.7 11.4 11 0 0 11 11 11 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74839.1 - 2.4e-22 78.4 70.0 0.00052 20.0 0.4 12.2 11 1 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74839.1 - 6.4e-22 77.3 57.7 0.0014 18.9 0.2 11.2 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM74839.1 - 2.6e-09 36.6 60.3 0.00019 21.1 0.7 11.2 11 0 0 11 11 11 4 C2H2-type zinc-finger domain BolA PF01722.18 KFM74839.1 - 1.3e-07 31.8 11.3 0.0041 17.4 0.1 5.9 4 3 1 5 5 5 2 BolA-like protein Baculo_IE-1 PF05290.11 KFM74839.1 - 2e-06 27.8 33.0 0.037 14.0 1.1 8.0 1 1 5 7 7 7 1 Baculovirus immediate-early protein (IE-0) zf-C2HC_2 PF13913.6 KFM74839.1 - 3.9e-06 26.6 29.5 2.7 8.0 0.1 9.7 9 0 0 9 9 9 2 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM74839.1 - 7.1e-05 23.5 37.3 0.23 12.3 3.0 5.7 2 1 4 6 6 6 4 zinc-ribbon family ADK_lid PF05191.14 KFM74839.1 - 0.00011 22.1 28.7 0.021 14.8 1.0 7.4 5 3 1 6 6 6 2 Adenylate kinase, active site lid zf_UBZ PF18439.1 KFM74839.1 - 0.0016 18.0 48.6 2.3 7.9 0.4 10.6 11 0 0 11 11 11 3 Ubiquitin-Binding Zinc Finger Zf_RING PF16744.5 KFM74839.1 - 0.002 18.2 44.4 2.1 8.5 0.1 9.9 1 1 9 10 10 9 2 KIAA1045 RING finger Complex1_49kDa PF00346.19 KFM74839.1 - 0.028 13.5 0.0 4.9 6.2 0.0 2.6 1 1 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-MYST PF17772.1 KFM74839.1 - 0.066 12.8 42.2 2 8.1 0.4 8.9 4 2 5 9 9 9 0 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 KFM74839.1 - 0.14 12.3 39.3 3.1 7.9 0.6 9.8 11 0 0 11 11 11 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 KFM74839.1 - 2.8 8.3 54.9 0.24 11.7 7.3 8.2 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 KFM74839.1 - 3.1 8.1 58.0 6.2 7.1 5.7 7.6 3 1 5 8 8 8 0 TFIIH C1-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM74840.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74840.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease p450 PF00067.22 KFM74841.1 - 3.6e-114 382.1 0.1 4.4e-114 381.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 SgrR_N PF12793.7 KFM74841.1 - 0.011 15.9 0.2 0.024 14.9 0.2 1.5 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term FixQ PF05545.11 KFM74841.1 - 0.03 14.3 0.9 0.078 13.0 0.9 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Beach PF02138.18 KFM74841.1 - 0.12 11.7 0.0 0.73 9.2 0.0 2.1 2 0 0 2 2 2 0 Beige/BEACH domain WW PF00397.26 KFM74842.1 - 1.4e-21 76.3 5.3 5e-10 39.3 2.3 2.6 2 0 0 2 2 2 2 WW domain FAM181 PF15238.6 KFM74842.1 - 1.2e-05 25.3 3.1 3e-05 24.0 3.1 1.6 1 0 0 1 1 1 1 FAM181 TFIIA PF03153.13 KFM74842.1 - 8.6 6.2 27.2 0.13 12.3 4.3 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit ArfGap PF01412.18 KFM74843.1 - 1e-26 93.3 0.0 2.2e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Surp PF01805.20 KFM74845.1 - 7.9e-20 70.6 0.1 2e-19 69.3 0.1 1.8 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 KFM74845.1 - 1.6e-14 53.4 0.0 3.5e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.12 KFM74845.1 - 1.1e-11 44.7 5.4 3.9e-11 42.9 5.4 2.1 1 0 0 1 1 1 1 cwf21 domain CTD_bind PF04818.13 KFM74845.1 - 3.2e-06 27.9 0.2 2.6e-05 25.0 0.2 2.7 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 KFM74845.1 - 6.7e-06 26.1 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 RRM_7 PF16367.5 KFM74845.1 - 0.064 13.4 0.0 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif Spore_III_AF PF09581.10 KFM74845.1 - 5.2 7.0 15.1 1.7 8.7 3.7 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Ig_3 PF13927.6 KFM74846.1 - 0.0054 17.3 0.0 0.0063 17.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain LRR_3 PF07725.12 KFM74847.1 - 0.033 14.0 0.2 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Leucine Rich Repeat Ig_3 PF13927.6 KFM74848.1 - 7e-38 129.1 0.0 3.6e-12 46.7 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 KFM74848.1 - 1.3e-36 124.5 0.0 2.5e-11 43.5 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM74848.1 - 4.8e-28 97.3 0.0 4.2e-08 33.4 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFM74848.1 - 2.6e-17 62.8 0.0 9.1e-05 22.6 0.0 3.8 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFM74848.1 - 1.6e-08 34.6 0.5 0.97 9.6 0.0 5.1 4 1 1 5 5 5 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM74848.1 - 2.2e-08 34.1 0.0 0.18 11.9 0.0 4.2 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM74848.1 - 1.1e-05 24.9 0.0 0.00038 20.0 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain Ig_5 PF16681.5 KFM74848.1 - 2.3e-05 24.7 0.0 0.017 15.5 0.0 3.3 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFM74848.1 - 0.0058 16.6 0.0 11 6.1 0.0 3.4 3 0 0 3 3 3 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFM74848.1 - 0.0067 16.5 0.0 6.1 7.0 0.0 3.0 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFM74848.1 - 0.031 14.3 0.0 5.7 6.9 0.0 2.7 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain Alveol-reg_P311 PF11092.8 KFM74848.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) HTH_Tnp_Tc3_2 PF01498.18 KFM74849.1 - 4e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74849.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74849.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74849.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74849.1 - 2.1 9.0 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain I-set PF07679.16 KFM74850.1 - 1.5e-11 44.2 0.2 0.00014 21.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM74850.1 - 2e-11 44.3 0.4 4.4e-07 30.4 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM74850.1 - 3e-11 43.3 0.1 2.1e-07 31.0 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM74850.1 - 2.1e-10 40.7 0.2 5.3e-05 23.4 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM74850.1 - 4e-10 39.6 0.1 6.2e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFM74850.1 - 5.6e-09 36.2 0.0 1.2e-06 28.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFM74850.1 - 3e-08 33.9 0.0 9e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM74850.1 - 0.00032 20.9 0.1 0.88 9.9 0.1 3.1 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM74850.1 - 0.048 14.1 0.1 2.6 8.5 0.2 2.6 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_3 PF13927.6 KFM74851.1 - 1.2e-14 54.7 1.5 2e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM74851.1 - 3.1e-12 46.7 0.3 2.9e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM74851.1 - 1.4e-10 41.1 0.2 1.1e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFM74851.1 - 3.8e-10 39.8 0.2 5e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM74851.1 - 4.7e-09 36.2 0.3 0.00017 21.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFM74851.1 - 0.00025 21.2 0.2 0.39 10.9 0.1 2.9 2 1 1 3 3 3 2 Immunoglobulin V-set domain Sushi PF00084.20 KFM74851.1 - 0.099 13.3 0.0 4.4 8.0 0.0 2.6 3 0 0 3 3 3 0 Sushi repeat (SCR repeat) Ig_4 PF16680.5 KFM74851.1 - 0.11 12.8 0.0 2.3 8.6 0.0 2.3 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Ig_3 PF13927.6 KFM74852.1 - 2.9e-48 162.4 0.1 2.5e-10 40.8 0.0 4.9 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFM74852.1 - 2.4e-42 142.9 0.0 2.3e-10 40.4 0.0 4.8 5 0 0 5 5 5 4 Immunoglobulin I-set domain ig PF00047.25 KFM74852.1 - 2.2e-31 107.9 0.9 1.4e-06 28.4 0.1 4.8 4 1 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFM74852.1 - 1.8e-28 98.7 0.0 4.4e-08 33.3 0.1 4.5 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 KFM74852.1 - 8.3e-11 42.1 0.2 2.3e-10 40.6 0.2 1.8 1 0 0 1 1 1 1 Fibronectin type III domain V-set PF07686.17 KFM74852.1 - 3.4e-09 36.8 2.4 3.2 8.0 0.0 6.0 4 3 1 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM74852.1 - 3.1e-08 33.6 0.5 7e-06 26.0 0.1 4.0 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFM74852.1 - 8.6e-05 22.5 0.1 14 5.8 0.1 6.0 6 1 0 6 6 6 0 C17orf99 Ig domain Ig_4 PF16680.5 KFM74852.1 - 0.00018 21.7 0.4 0.49 10.7 0.2 4.4 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM74852.1 - 0.00046 20.5 1.2 1.9 9.0 0.2 4.1 4 1 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFM74852.1 - 0.00053 20.3 0.0 1.2 9.6 0.0 4.0 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFM74852.1 - 0.051 13.6 0.0 8.3 6.6 0.0 3.6 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain TMEM154 PF15102.6 KFM74852.1 - 0.14 12.1 0.4 0.7 9.8 0.0 2.1 1 1 1 2 2 2 0 TMEM154 protein family Ig_6 PF18452.1 KFM74852.1 - 0.15 11.6 0.0 1.7 8.3 0.0 2.7 3 0 0 3 3 3 0 Immunoglobulin domain Ion_trans_2 PF07885.16 KFM74853.1 - 4.8e-20 71.3 3.2 5.6e-20 71.1 3.2 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFM74853.1 - 0.0092 15.2 1.2 0.01 15.1 1.2 1.1 1 0 0 1 1 1 1 Ion transport protein zf-LITAF-like PF10601.9 KFM74853.1 - 0.13 12.6 0.4 0.21 11.9 0.1 1.5 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain MAS20 PF02064.15 KFM74854.1 - 2.2e-39 134.5 0.0 3.1e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 MAS20 protein import receptor Wzz PF02706.15 KFM74855.1 - 8.9 6.7 12.6 37 4.7 0.1 4.8 4 0 0 4 4 4 0 Chain length determinant protein Ank_2 PF12796.7 KFM74856.1 - 1.3e-25 89.8 0.3 4.1e-11 43.3 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM74856.1 - 5.7e-22 77.8 4.0 9.1e-07 29.3 0.0 6.1 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM74856.1 - 4.4e-19 66.6 2.0 7.6e-05 22.8 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KFM74856.1 - 2.8e-17 62.3 7.2 0.00038 20.8 0.2 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFM74856.1 - 5.4e-16 58.5 3.6 0.00029 21.1 0.0 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 KFM74856.1 - 0.00085 19.2 0.1 0.0026 17.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) p450 PF00067.22 KFM74858.1 - 4.2e-20 71.9 0.0 4.4e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM74859.1 - 4.4e-10 38.9 0.2 4.9e-10 38.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM74860.1 - 9.3e-06 24.6 0.0 1.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.27 KFM74861.1 - 4.2e-06 26.4 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM74861.1 - 0.00071 19.8 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF5641 PF18701.1 KFM74861.1 - 0.0014 18.7 2.4 0.0027 17.8 2.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) ALS2CR8 PF15299.6 KFM74861.1 - 0.11 12.4 0.4 0.18 11.7 0.4 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 RRM_1 PF00076.22 KFM74863.1 - 2.8e-18 65.5 0.0 4.1e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFM74863.1 - 6e-06 26.1 5.2 1.4e-05 24.9 5.2 1.7 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 KFM74863.1 - 0.00018 21.1 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_5 PF14787.6 KFM74863.1 - 0.0021 17.7 2.6 0.0061 16.2 2.6 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RRM_occluded PF16842.5 KFM74863.1 - 0.053 13.4 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-CCHC_3 PF13917.6 KFM74863.1 - 0.35 10.9 2.9 0.71 9.9 2.9 1.6 1 1 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 KFM74864.1 - 0.0042 17.3 0.0 0.0049 17.1 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein MFS_1 PF07690.16 KFM74865.1 - 1e-14 54.3 1.4 1e-14 54.2 1.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Myb_DNA-bind_5 PF13873.6 KFM74866.1 - 3e-09 36.8 0.1 5.9e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFM74866.1 - 6.7e-05 23.2 0.2 8.4e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM74866.1 - 0.0053 17.1 0.1 0.0073 16.6 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3020 PF11223.8 KFM74866.1 - 0.15 12.6 7.0 0.82 10.2 6.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3020) FPN1 PF06963.12 KFM74870.1 - 0.054 12.0 0.0 0.062 11.9 0.0 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Ldl_recept_a PF00057.18 KFM74871.1 - 3.1e-34 116.9 73.0 7.7e-11 42.0 8.9 5.4 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A EB PF01683.18 KFM74871.1 - 0.0023 18.2 12.7 0.0023 18.2 12.7 6.7 1 1 4 5 5 5 1 EB module EB PF01683.18 KFM74872.1 - 1.7e-07 31.4 2.1 2e-07 31.2 2.1 1.1 1 0 0 1 1 1 1 EB module cEGF PF12662.7 KFM74872.1 - 0.01 15.8 1.3 0.01 15.8 1.3 1.7 2 0 0 2 2 2 1 Complement Clr-like EGF-like DDE_3 PF13358.6 KFM74874.1 - 1.4e-14 54.0 0.0 2.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74874.1 - 2.4e-08 34.1 0.2 4.8e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Transposase Peptidase_M14 PF00246.24 KFM74875.1 - 6e-74 249.5 0.0 8.2e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFM74875.1 - 4.4e-14 52.5 0.2 8.4e-14 51.6 0.2 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFM74875.1 - 4.4e-09 36.2 0.0 9.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KFM74875.1 - 0.004 16.3 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family HTH_Tnp_Tc3_2 PF01498.18 KFM74878.1 - 4.9e-16 58.7 2.2 4.9e-16 58.7 2.2 2.3 2 1 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74878.1 - 8.8e-14 51.5 0.0 1.8e-13 50.5 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease RabGAP-TBC PF00566.18 KFM74879.1 - 1.8e-56 191.2 0.2 1.8e-56 191.2 0.2 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Fis1_TPR_C PF14853.6 KFM74880.1 - 6.2e-24 83.8 1.6 1.2e-23 82.9 1.6 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KFM74880.1 - 1.3e-15 56.7 0.0 3.3e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KFM74880.1 - 7.4e-05 22.6 0.1 0.00021 21.1 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM74880.1 - 0.0027 17.4 0.2 0.0072 16.1 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM74880.1 - 0.018 15.3 0.1 0.046 13.9 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFM74880.1 - 0.029 15.0 0.1 0.15 12.8 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Paf67 PF10255.9 KFM74880.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 ETRAMP PF09716.10 KFM74880.1 - 0.038 14.0 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Serpin PF00079.20 KFM74881.1 - 1.3e-67 228.7 0.1 1.5e-67 228.5 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Adhes-Ig_like PF09085.10 KFM74881.1 - 0.18 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like DDE_Tnp_1_7 PF13843.6 KFM74882.1 - 9.2e-16 58.1 0.0 2.3e-15 56.8 0.0 1.6 1 1 0 1 1 1 1 Transposase IS4 DHHC PF01529.20 KFM74883.1 - 2.8e-25 89.0 14.6 2.8e-25 89.0 14.6 2.2 2 1 1 3 3 3 1 DHHC palmitoyltransferase UBA PF00627.31 KFM74884.1 - 1.7e-10 40.6 0.0 3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 KFM74884.1 - 0.00016 21.7 1.6 0.00031 20.8 1.6 1.5 1 0 0 1 1 1 1 Rhomboid family UBA_3 PF09288.10 KFM74884.1 - 0.003 17.3 0.0 0.01 15.6 0.0 1.9 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DER1 PF04511.15 KFM74884.1 - 0.33 10.8 7.8 0.54 10.2 7.8 1.4 1 1 0 1 1 1 0 Der1-like family CUE PF02845.16 KFM74884.1 - 0.33 10.7 1.8 0.78 9.5 1.8 1.7 1 1 0 1 1 1 0 CUE domain Bcl-2 PF00452.19 KFM74886.1 - 7.5e-25 87.5 0.0 1.2e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Pro_isomerase PF00160.21 KFM74887.1 - 1.5e-54 184.5 0.0 1.7e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DM4_12 PF07841.13 KFM74889.1 - 0.00049 20.7 0.2 0.0011 19.5 0.2 1.6 1 0 0 1 1 1 1 DM4/DM12 family Motile_Sperm PF00635.26 KFM74890.1 - 8.3e-11 41.7 0.5 1.6e-10 40.8 0.4 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain DUF2116 PF09889.9 KFM74890.1 - 0.083 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RRM_1 PF00076.22 KFM74891.1 - 3.6e-07 29.9 0.2 6.9e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 KFM74891.1 - 0.0014 18.5 1.5 0.0021 17.9 0.3 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFM74891.1 - 0.0089 16.7 0.9 0.0089 16.7 0.9 2.9 2 2 0 2 2 2 1 Torus domain Granulin PF00396.18 KFM74891.1 - 0.19 12.1 0.3 0.37 11.2 0.3 1.4 1 0 0 1 1 1 0 Granulin Macoilin PF09726.9 KFM74891.1 - 3.5 6.1 21.3 4.2 5.8 21.3 1.0 1 0 0 1 1 1 0 Macoilin family 7tm_2 PF00002.24 KFM74893.1 - 7.4e-20 71.3 5.1 7.7e-20 71.2 5.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1746 PF08508.10 KFM74893.1 - 0.0099 16.2 1.1 0.015 15.6 1.1 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) MULE PF10551.9 KFM74894.1 - 2e-13 50.5 0.3 5.6e-13 49.1 0.3 1.8 1 0 0 1 1 1 1 MULE transposase domain Condensin2nSMC PF12422.8 KFM74894.1 - 0.046 13.9 5.0 0.7 10.1 1.2 3.5 2 1 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit zf-C2H2 PF00096.26 KFM74895.1 - 1.7e-07 31.3 8.1 0.00041 20.7 0.8 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74895.1 - 1e-05 25.9 7.8 0.0011 19.6 0.7 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.15 KFM74895.1 - 0.0045 17.0 4.5 0.0054 16.7 1.2 2.3 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_6 PF13912.6 KFM74895.1 - 0.011 15.7 4.2 0.61 10.2 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74895.1 - 0.013 15.8 0.9 0.013 15.8 0.9 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM74895.1 - 0.016 15.5 6.1 0.03 14.7 1.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KFM74895.1 - 0.031 14.9 1.6 2.2 9.0 0.1 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-met PF12874.7 KFM74895.1 - 0.041 14.3 1.5 0.35 11.3 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFM74895.1 - 0.19 12.2 0.7 0.19 12.2 0.7 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Ribosomal_S10 PF00338.22 KFM74896.1 - 7.2e-24 83.9 0.1 1.2e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PC-Esterase PF13839.6 KFM74896.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Ras PF00071.22 KFM74897.1 - 1e-66 223.5 0.4 1.2e-66 223.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM74897.1 - 1.3e-37 128.7 0.1 1.9e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM74897.1 - 1.2e-17 63.9 0.1 1.6e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM74897.1 - 9.3e-07 28.6 0.2 2.8e-06 27.0 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM74897.1 - 4.1e-06 26.8 0.4 0.077 12.9 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 KFM74897.1 - 1.2e-05 24.8 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM74897.1 - 1.6e-05 24.9 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFM74897.1 - 6.3e-05 22.5 0.0 9.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KFM74897.1 - 0.0012 19.3 0.0 0.051 14.0 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KFM74897.1 - 0.0021 17.6 0.0 0.011 15.3 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFM74897.1 - 0.012 16.1 0.0 0.016 15.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KFM74897.1 - 0.022 14.5 0.1 0.99 9.1 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KFM74897.1 - 0.039 14.2 0.0 0.088 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM74897.1 - 0.05 14.1 0.0 0.078 13.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 KFM74897.1 - 0.059 13.4 0.1 0.081 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KFM74897.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFM74897.1 - 0.065 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region LANC_like PF05147.13 KFM74897.1 - 0.078 11.5 0.0 0.16 10.5 0.0 1.5 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein Septin PF00735.18 KFM74897.1 - 0.08 12.2 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Septin TniB PF05621.11 KFM74897.1 - 0.09 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Dioxygenase_N PF04444.14 KFM74897.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Catechol dioxygenase N terminus RHD_DNA_bind PF00554.22 KFM74898.1 - 5.2e-62 208.8 0.0 1.1e-61 207.7 0.0 1.6 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFM74898.1 - 6.4e-31 106.4 0.1 1.6e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 Rel homology dimerisation domain DUF1490 PF07371.12 KFM74898.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) DUF883 PF05957.13 KFM74899.1 - 0.088 13.4 0.0 0.096 13.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Cyclin_N PF00134.23 KFM74900.1 - 4.3e-06 26.5 3.7 0.024 14.4 0.9 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFM74900.1 - 0.00013 22.1 0.8 0.023 14.8 0.2 2.7 2 0 0 2 2 2 2 Cyclin, C-terminal domain PQQ_2 PF13360.6 KFM74901.1 - 3.1e-10 40.0 0.1 4.5e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KFM74901.1 - 0.0073 16.2 0.0 1.1 9.3 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat PCC_BT PF18140.1 KFM74901.1 - 0.02 15.2 0.1 0.084 13.2 0.0 2.0 2 0 0 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain DUF603 PF04645.12 KFM74901.1 - 0.66 9.7 4.3 14 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF603 CH PF00307.31 KFM74902.1 - 6.8e-90 296.5 2.3 2.4e-22 79.2 0.2 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KFM74902.1 - 1.5e-09 38.2 0.2 6.2e-09 36.2 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 KFM74902.1 - 1.7e-09 37.4 1.3 1.5e-05 24.7 0.1 3.9 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_6 PF13405.6 KFM74902.1 - 1.7e-07 30.6 0.3 0.0031 17.3 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KFM74902.1 - 3.7e-06 26.1 0.6 0.03 13.9 0.0 3.3 3 0 0 3 3 3 2 EF hand CH_2 PF06294.11 KFM74902.1 - 0.00015 21.8 0.5 3.4 7.8 0.0 4.1 4 0 0 4 4 4 2 CH-like domain in sperm protein EF-hand_5 PF13202.6 KFM74902.1 - 0.0029 17.0 3.0 0.38 10.3 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFM74902.1 - 0.0031 17.3 0.2 3.8 7.4 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair PgpA PF04608.13 KFM74902.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylglycerophosphatase A DUF1866 PF08952.11 KFM74903.1 - 2.3e-19 69.7 0.0 4.8e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 KFM74903.1 - 5.8e-13 48.9 0.0 1.5e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Syja_N PF02383.18 KFM74904.1 - 2.5e-31 109.2 0.1 2.6e-31 109.2 0.1 1.0 1 0 0 1 1 1 1 SacI homology domain zf-CCCH PF00642.24 KFM74905.1 - 1.3e-23 82.3 15.9 5.2e-12 45.4 2.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM74905.1 - 1.1e-11 44.4 16.2 2.6e-07 30.5 2.8 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFM74905.1 - 1.5e-07 31.0 14.8 7.6e-05 22.4 1.7 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KFM74905.1 - 0.00057 20.6 9.3 0.12 13.1 2.1 2.4 1 1 1 2 2 2 2 Torus domain Tis11B_N PF04553.12 KFM74905.1 - 0.0013 19.3 0.2 0.0025 18.3 0.2 1.5 1 0 0 1 1 1 1 Tis11B like protein, N terminus zf-CCCH_2 PF14608.6 KFM74905.1 - 0.0013 19.1 14.9 0.063 13.8 1.5 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger oligo_HPY PF08352.12 KFM74905.1 - 0.046 14.3 3.4 2.9 8.5 0.4 2.6 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-H2C2_2 PF13465.6 KFM74906.1 - 3.3e-64 210.6 119.2 9.4e-09 35.3 0.7 16.3 16 0 0 16 16 16 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74906.1 - 4.4e-54 178.0 159.7 3.3e-06 27.2 3.3 16.0 17 1 0 17 17 15 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74906.1 - 3e-42 139.6 144.9 0.00038 21.1 0.3 16.6 16 1 1 17 17 17 13 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM74906.1 - 7.4e-24 83.2 136.0 0.00018 21.4 0.8 16.7 18 0 0 18 18 18 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74906.1 - 5.9e-17 61.5 112.4 0.01 16.1 0.4 14.2 12 2 3 15 15 14 11 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM74906.1 - 3.8e-16 58.9 138.1 0.004 17.5 1.5 15.8 16 0 0 16 16 16 11 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM74906.1 - 1.3e-10 40.9 106.3 0.00026 20.7 2.3 14.0 14 1 0 14 14 14 10 C2H2-type zinc-finger domain BolA PF01722.18 KFM74906.1 - 0.00027 21.2 25.1 1.8 8.9 0.1 8.3 4 3 5 9 9 9 1 BolA-like protein zf-C2H2_11 PF16622.5 KFM74906.1 - 0.0019 17.9 0.1 0.0019 17.9 0.1 13.1 13 1 1 14 14 14 3 zinc-finger C2H2-type zf-BED PF02892.15 KFM74906.1 - 0.0056 16.7 3.3 0.0056 16.7 3.3 12.6 4 4 8 12 12 11 4 BED zinc finger UPF0728 PF15092.6 KFM74906.1 - 1.1 9.2 11.9 1.9 8.4 0.1 4.8 4 2 1 5 5 5 0 Uncharacterised protein family UPF0728 zf-C2H2_2 PF12756.7 KFM74906.1 - 2.4 8.5 108.2 0.24 11.7 1.6 11.4 1 1 10 11 11 11 0 C2H2 type zinc-finger (2 copies) Nop52 PF05997.12 KFM74907.1 - 4.1e-25 88.8 4.1 4.5e-25 88.7 4.1 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Nop52 PF05997.12 KFM74908.1 - 1.2e-25 90.6 0.2 1.8e-25 90.0 0.2 1.4 1 1 0 1 1 1 1 Nucleolar protein,Nop52 zf-RING_2 PF13639.6 KFM74909.1 - 3.5e-10 40.0 9.7 3.5e-10 40.0 9.7 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KFM74909.1 - 7.3e-09 35.8 8.0 7.3e-09 35.8 8.0 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFM74909.1 - 6.4e-07 29.1 9.3 6.4e-07 29.1 9.3 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM74909.1 - 4.3e-05 23.3 10.4 4.3e-05 23.3 10.4 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM74909.1 - 0.00047 19.8 7.2 0.00047 19.8 7.2 3.0 4 0 0 4 4 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFM74909.1 - 0.00074 19.3 7.2 0.00074 19.3 7.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM74909.1 - 0.0013 18.6 8.7 0.0013 18.6 8.7 2.7 3 0 0 3 3 2 1 zinc-RING finger domain PAM2 PF07145.15 KFM74909.1 - 0.0015 18.1 0.4 0.79 9.5 0.1 3.0 2 0 0 2 2 2 1 Ataxin-2 C-terminal region zf-ANAPC11 PF12861.7 KFM74909.1 - 0.0017 18.3 1.8 0.0017 18.3 1.8 1.9 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFM74909.1 - 0.0076 15.9 7.1 0.0076 15.9 7.1 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type DUF4651 PF15513.6 KFM74909.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) zf-RING_10 PF16685.5 KFM74909.1 - 0.26 11.5 4.9 0.92 9.7 4.9 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KFM74909.1 - 0.4 10.9 6.3 1.6 8.9 5.5 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFM74909.1 - 2.7 8.1 14.0 0.16 12.1 8.0 2.2 2 0 0 2 2 1 0 RING-type zinc-finger RINGv PF12906.7 KFM74909.1 - 8.1 6.7 10.0 24 5.2 10.0 1.8 1 0 0 1 1 1 0 RING-variant domain zf-HC5HC2H PF13771.6 KFM74909.1 - 8.2 6.8 14.5 1.8 8.9 2.2 3.5 3 0 0 3 3 3 0 PHD-like zinc-binding domain TPR_1 PF00515.28 KFM74910.1 - 3.2e-08 33.0 4.2 0.069 13.0 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM74910.1 - 5.5e-06 26.1 9.4 0.022 14.8 0.1 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM74910.1 - 1.8e-05 25.3 1.2 0.0018 18.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM74910.1 - 9e-05 22.9 0.5 0.0049 17.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM74910.1 - 0.0056 16.6 2.2 2.5 8.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM74910.1 - 0.022 14.9 13.2 1 9.7 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM74910.1 - 0.083 13.2 1.9 39 4.6 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM74910.1 - 1.1 9.0 10.0 16 5.3 1.4 4.3 3 1 1 4 4 4 0 TPR repeat RUN PF02759.19 KFM74913.1 - 2.7e-27 95.4 0.0 2.7e-27 95.4 0.0 2.4 3 1 0 3 3 3 1 RUN domain FYVE PF01363.21 KFM74913.1 - 7.9e-20 70.8 10.4 1.8e-19 69.6 10.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger Trimer_CC PF08954.11 KFM74913.1 - 0.0085 15.6 5.0 2.1 7.9 0.3 4.1 3 1 0 3 3 3 1 Trimerisation motif Zn_Tnp_IS1595 PF12760.7 KFM74913.1 - 0.021 14.8 2.9 0.059 13.4 2.9 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain IBR PF01485.21 KFM74913.1 - 0.031 14.5 6.9 0.082 13.1 6.9 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Spc7 PF08317.11 KFM74913.1 - 0.23 10.3 57.4 0.037 12.9 13.8 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein ApoO PF09769.9 KFM74913.1 - 0.52 10.3 7.8 2.8 7.9 0.1 3.9 3 1 1 4 4 4 0 Apolipoprotein O DUF1664 PF07889.12 KFM74913.1 - 1 9.4 32.8 1.1 9.3 5.1 5.0 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) HypA PF01155.19 KFM74913.1 - 1.2 9.2 9.5 2.1 8.4 7.9 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PspA_IM30 PF04012.12 KFM74913.1 - 2.9 7.4 39.3 0.089 12.4 21.3 3.8 2 2 1 3 3 3 0 PspA/IM30 family DZR PF12773.7 KFM74913.1 - 3.3 7.8 11.8 30 4.7 0.9 2.6 1 1 1 2 2 2 0 Double zinc ribbon Orbi_VP5 PF00901.17 KFM74913.1 - 3.5 5.9 13.8 0.11 10.8 7.3 1.7 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 Rootletin PF15035.6 KFM74913.1 - 6.7 6.7 46.4 8.8 6.3 10.9 3.8 1 1 2 3 3 2 0 Ciliary rootlet component, centrosome cohesion Formyl_trans_C PF02911.18 KFM74915.1 - 3.4e-10 40.0 0.0 4.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF1759 PF03564.15 KFM74917.1 - 6.1e-09 36.0 1.2 8.1e-09 35.6 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) T4_baseplate PF12322.8 KFM74918.1 - 0.062 12.8 0.3 0.069 12.6 0.3 1.0 1 0 0 1 1 1 0 T4 bacteriophage base plate protein zf-H2C2_2 PF13465.6 KFM74919.1 - 4.9e-11 42.5 8.2 3.6e-05 24.0 0.1 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74919.1 - 9.5e-10 38.4 15.8 0.00014 22.1 0.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM74919.1 - 1.4e-09 37.7 9.8 2.8e-05 24.0 0.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFM74919.1 - 1.5e-09 37.9 10.8 0.00035 21.2 0.7 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KFM74919.1 - 6.6e-05 23.1 3.5 0.0061 16.8 0.4 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Baculo_IE-1 PF05290.11 KFM74919.1 - 0.00024 21.0 3.4 0.045 13.7 1.0 2.0 1 1 1 2 2 2 2 Baculovirus immediate-early protein (IE-0) zf-C2H2_2 PF12756.7 KFM74919.1 - 0.0024 18.2 5.0 0.12 12.8 0.2 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM74919.1 - 0.0046 16.8 0.5 1.5 8.7 0.0 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 KFM74919.1 - 0.0092 16.2 6.2 0.84 10.0 0.6 2.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM74919.1 - 0.012 16.0 11.5 0.49 10.9 2.2 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.12 KFM74919.1 - 0.014 15.4 5.5 0.74 9.8 1.6 2.1 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger GAGA PF09237.11 KFM74919.1 - 0.015 15.1 3.4 0.16 11.8 0.2 2.2 1 1 1 2 2 2 0 GAGA factor C1_1 PF00130.22 KFM74919.1 - 0.02 14.7 1.9 0.026 14.4 0.8 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_SprT PF17283.2 KFM74919.1 - 0.027 14.4 8.7 0.38 10.7 2.7 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-RING_11 PF17123.5 KFM74919.1 - 0.049 13.4 0.4 3.3 7.5 0.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger HypA PF01155.19 KFM74919.1 - 0.049 13.6 2.7 0.24 11.4 0.6 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-MYST PF17772.1 KFM74919.1 - 0.054 13.1 6.4 0.25 11.0 0.1 2.3 1 1 1 2 2 2 0 MYST family zinc finger domain zf_C2H2_ZHX PF18387.1 KFM74919.1 - 0.067 12.8 2.3 2.5 7.8 0.1 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_8 PF15909.5 KFM74919.1 - 0.1 12.9 6.5 0.44 10.9 6.7 1.7 1 1 0 1 1 1 0 C2H2-type zinc ribbon Zf_RING PF16744.5 KFM74919.1 - 0.72 10.0 5.9 16 5.7 5.8 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger DUF3449 PF11931.8 KFM74919.1 - 1.3 8.7 5.6 1.9 8.3 2.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) zf-BED PF02892.15 KFM74919.1 - 8.4 6.5 14.1 3.4 7.8 4.4 2.9 1 1 2 3 3 3 0 BED zinc finger DDE_Tnp_IS1595 PF12762.7 KFM74920.1 - 0.095 12.7 0.0 0.095 12.7 0.0 1.1 1 0 0 1 1 1 0 ISXO2-like transposase domain zf-H2C2_2 PF13465.6 KFM74921.1 - 2.8e-67 220.3 61.7 2.8e-10 40.2 0.6 10.8 11 0 0 11 11 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74921.1 - 1.8e-56 185.5 81.6 4.1e-07 30.1 0.5 10.3 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74921.1 - 1.8e-36 121.6 74.0 0.00042 20.9 0.4 10.2 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM74921.1 - 6.9e-23 80.3 61.8 0.0052 17.1 0.6 10.4 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74921.1 - 1.1e-16 60.3 57.9 0.03 14.3 1.7 10.9 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74921.1 - 2.5e-15 56.3 56.1 0.012 15.8 0.6 10.5 7 3 3 10 10 10 6 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM74921.1 - 2.8e-05 24.0 36.4 0.43 10.6 1.5 7.7 6 2 2 8 8 8 5 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 KFM74921.1 - 4.2e-05 23.4 27.6 4.4 7.3 0.0 9.5 10 0 0 10 10 10 1 Prokaryotic RING finger family 1 zf-H2C2_5 PF13909.6 KFM74921.1 - 9e-05 22.1 51.2 0.0097 15.6 0.5 9.4 9 1 0 9 9 9 3 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM74921.1 - 0.00018 21.8 54.9 0.044 14.1 10.7 7.5 1 1 4 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.15 KFM74921.1 - 0.0017 18.4 35.6 1.4 9.0 0.6 9.4 9 1 1 10 10 10 1 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM74921.1 - 0.0022 17.8 28.2 0.76 9.6 0.1 7.5 3 3 5 8 8 8 3 GAGA factor DUF4712 PF15830.5 KFM74921.1 - 0.0051 16.5 0.2 0.019 14.7 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4712) Zn-ribbon_8 PF09723.10 KFM74921.1 - 0.02 15.0 26.8 0.32 11.2 0.8 5.6 5 1 0 5 5 5 0 Zinc ribbon domain zf_ZIC PF18366.1 KFM74921.1 - 0.023 14.8 37.7 6.2 7.0 0.1 7.9 3 3 5 8 8 8 0 Zic proteins zinc finger domain zf-BED PF02892.15 KFM74921.1 - 0.023 14.7 1.0 0.023 14.7 1.0 9.9 1 1 9 10 10 10 0 BED zinc finger BolA PF01722.18 KFM74921.1 - 0.037 14.3 10.2 3 8.2 0.0 4.6 3 3 2 5 5 5 0 BolA-like protein zf-RRPl_C4 PF17026.5 KFM74921.1 - 0.042 13.9 30.1 0.35 11.0 2.7 4.6 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-FCS PF06467.14 KFM74921.1 - 0.2 11.6 0.3 0.2 11.6 0.3 7.8 8 1 2 10 10 10 0 MYM-type Zinc finger with FCS sequence motif zf_UBZ PF18439.1 KFM74921.1 - 0.46 10.1 38.9 12 5.6 0.1 9.6 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM74921.1 - 0.48 10.1 0.0 0.48 10.1 0.0 7.7 5 3 4 9 9 9 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFM74921.1 - 0.59 10.9 34.7 2.8 8.7 1.3 5.2 2 2 3 5 5 5 0 zinc-ribbon family zinc_ribbon_9 PF14369.6 KFM74921.1 - 0.59 10.4 21.2 28 5.1 0.1 8.1 10 0 0 10 10 10 0 zinc-ribbon zf-C2HC_2 PF13913.6 KFM74921.1 - 0.79 9.7 37.5 4.3 7.3 0.1 9.7 11 0 0 11 11 10 0 zinc-finger of a C2HC-type PHF5 PF03660.14 KFM74921.1 - 0.84 9.9 28.8 3.8 7.8 1.0 5.1 1 1 4 5 5 5 0 PHF5-like protein DUF2256 PF10013.9 KFM74921.1 - 0.95 9.6 35.7 1.9 8.6 0.4 9.3 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) YyzF PF14116.6 KFM74921.1 - 2.5 8.2 32.3 5.3 7.1 0.1 8.9 8 2 2 10 10 10 0 YyzF-like protein Flag1_repress PF03614.13 KFM74921.1 - 7.5 6.3 6.4 28 4.4 0.1 3.4 1 1 2 3 3 3 0 Repressor of phase-1 flagellin zf-H2C2_2 PF13465.6 KFM74922.1 - 1.6e-63 208.4 63.6 2e-08 34.3 0.1 11.5 11 1 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74922.1 - 2.1e-49 163.3 91.3 1.7e-05 25.0 0.7 11.1 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74922.1 - 4.2e-33 111.2 81.9 0.0024 18.5 0.4 11.0 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM74922.1 - 2.9e-22 78.1 62.4 0.0016 18.4 0.2 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74922.1 - 3.4e-22 78.2 55.8 0.02 15.2 1.3 10.4 10 0 0 10 10 10 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM74922.1 - 5.2e-21 74.3 65.5 0.00047 20.5 2.0 10.5 10 0 0 10 10 10 9 Zinc-finger of C2H2 type GAGA PF09237.11 KFM74922.1 - 6.7e-08 32.2 22.4 0.87 9.4 0.0 7.2 2 2 7 9 9 9 4 GAGA factor Prok-RING_1 PF14446.6 KFM74922.1 - 2.7e-05 24.0 31.6 3.7 7.5 0.1 9.8 9 1 0 9 9 9 1 Prokaryotic RING finger family 1 HNH_5 PF14279.6 KFM74922.1 - 4.2e-05 23.3 36.9 0.068 13.0 1.3 9.2 6 4 1 7 7 7 1 HNH endonuclease zf-C2HC_2 PF13913.6 KFM74922.1 - 0.00057 19.7 41.5 0.095 12.6 0.1 9.3 10 0 0 10 10 10 3 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM74922.1 - 0.0019 18.1 29.9 3.8 7.6 1.1 6.9 4 3 1 5 5 5 2 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM74922.1 - 0.0031 17.8 57.2 1.4 9.3 2.2 8.0 1 1 5 7 7 7 2 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM74922.1 - 0.0063 17.2 29.2 1.8 9.3 2.8 5.5 2 1 3 5 5 5 2 zinc-ribbon family zf-C2H2_3rep PF18868.1 KFM74922.1 - 0.0092 16.7 34.1 1.5 9.5 1.1 7.2 3 3 1 4 4 3 2 Zinc finger C2H2-type, 3 repeats zinc_ribbon_9 PF14369.6 KFM74922.1 - 0.017 15.4 29.6 4.5 7.6 0.0 9.3 9 1 1 10 10 10 0 zinc-ribbon Imm25 PF15564.6 KFM74922.1 - 0.04 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Immunity protein 25 zf-MYST PF17772.1 KFM74922.1 - 0.047 13.3 0.5 0.047 13.3 0.5 8.3 6 3 4 10 10 10 0 MYST family zinc finger domain zf_UBZ PF18439.1 KFM74922.1 - 0.071 12.7 37.0 2.7 7.7 0.1 9.4 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger Baculo_IE-1 PF05290.11 KFM74922.1 - 0.083 12.8 28.6 0.88 9.5 2.3 7.0 1 1 5 6 6 6 0 Baculovirus immediate-early protein (IE-0) Zn-ribbon_8 PF09723.10 KFM74922.1 - 0.091 12.9 24.4 1.1 9.4 0.1 6.7 3 3 5 8 8 8 0 Zinc ribbon domain C5HCH PF17982.1 KFM74922.1 - 0.12 12.6 36.2 6.2 7.1 0.5 9.7 9 1 1 10 10 10 0 NSD Cys-His rich domain VATC PF18716.1 KFM74922.1 - 0.48 10.3 30.5 6.2 6.8 0.1 9.4 10 0 0 10 10 10 0 Vms1-associating treble clef domain zf_ZIC PF18366.1 KFM74922.1 - 0.51 10.5 47.8 0.9 9.7 0.5 9.9 3 3 8 11 11 11 0 Zic proteins zinc finger domain PHF5 PF03660.14 KFM74922.1 - 0.65 10.2 26.7 3.4 7.9 0.5 5.5 1 1 6 7 7 7 0 PHF5-like protein DUF2256 PF10013.9 KFM74922.1 - 0.83 9.8 34.6 11 6.2 0.1 9.5 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_1 PF00130.22 KFM74922.1 - 1.5 8.7 50.1 5.7 6.9 3.3 9.1 1 1 7 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Sec23_Sec24 PF04810.15 KFM74922.1 - 2.7 8.1 39.2 4.7 7.3 0.2 8.9 8 1 2 10 10 10 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.6 KFM74923.1 - 2.3e-23 81.5 59.1 3.5e-06 27.2 5.6 7.3 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74923.1 - 5e-20 70.8 57.0 0.00012 22.3 5.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74923.1 - 4.7e-17 61.2 50.4 0.0043 17.8 4.5 6.4 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74923.1 - 3e-12 46.5 41.4 0.0023 18.2 0.9 6.5 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM74923.1 - 2.4e-10 40.4 37.3 0.0021 18.4 0.8 6.4 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74923.1 - 9.1e-06 25.5 39.3 0.0047 16.9 2.0 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFM74923.1 - 0.015 16.0 25.8 0.75 10.5 1.2 4.3 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 KFM74923.1 - 0.056 13.7 2.1 17 5.8 0.6 4.1 1 1 1 2 2 2 0 BolA-like protein zf-C2HC_2 PF13913.6 KFM74923.1 - 0.094 12.6 22.7 1.2 9.1 0.1 6.0 6 0 0 6 6 6 0 zinc-finger of a C2HC-type XPA_N PF01286.18 KFM74923.1 - 0.19 11.8 20.0 39 4.4 0.1 6.3 6 0 0 6 6 6 0 XPA protein N-terminal zf-C2H2_11 PF16622.5 KFM74923.1 - 0.91 9.3 0.0 0.91 9.3 0.0 5.8 6 0 0 6 6 6 0 zinc-finger C2H2-type Acyltransf_C PF16076.5 KFM74923.1 - 0.92 9.6 7.7 0.23 11.5 0.5 3.1 3 1 0 3 3 3 0 Acyltransferase C-terminus zf-Paramyx-P PF13008.7 KFM74923.1 - 2.3 7.7 9.6 24 4.5 0.1 3.1 2 1 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein Laminin_G_2 PF02210.24 KFM74924.1 - 8.4e-33 113.6 0.6 4.5e-29 101.6 0.1 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFM74924.1 - 1.7e-25 89.7 0.0 2.1e-22 79.8 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFM74924.1 - 1.7e-05 25.0 4.5 3e-05 24.2 4.5 1.4 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFM74924.1 - 0.00068 20.2 1.8 0.00068 20.2 1.8 1.9 2 0 0 2 2 2 1 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 KFM74924.1 - 0.016 15.5 1.8 0.027 14.8 1.8 1.4 1 0 0 1 1 1 0 Pvs28 EGF domain EGF_2 PF07974.13 KFM74924.1 - 0.023 15.1 7.0 0.04 14.3 7.0 1.4 1 0 0 1 1 1 0 EGF-like domain zf-H2C2_2 PF13465.6 KFM74928.1 - 1.3e-106 344.7 139.6 3.3e-08 33.6 1.6 18.1 18 0 0 18 18 18 18 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74928.1 - 2.7e-69 226.0 169.0 2e-05 24.8 3.3 18.1 18 0 0 18 18 18 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74928.1 - 2.7e-47 155.3 157.8 0.00012 22.6 1.8 18.1 18 0 0 18 18 18 17 C2H2-type zinc finger zf-met PF12874.7 KFM74928.1 - 1.5e-28 98.3 139.6 0.0026 18.1 1.7 18.1 18 0 0 18 18 18 12 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74928.1 - 1.1e-21 76.3 144.2 0.0061 16.5 1.6 18.9 18 1 0 18 18 18 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74928.1 - 3.5e-11 43.1 115.7 0.0072 16.6 1.1 17.7 17 1 1 18 18 18 8 Zinc-finger double-stranded RNA-binding C1_1 PF00130.22 KFM74928.1 - 4e-07 29.8 101.7 0.29 11.0 4.2 13.3 7 3 6 13 13 13 8 Phorbol esters/diacylglycerol binding domain (C1 domain) BHD_1 PF10403.9 KFM74928.1 - 0.00014 21.6 2.4 0.66 9.9 0.4 5.3 3 2 1 4 4 4 1 Rad4 beta-hairpin domain 1 BolA PF01722.18 KFM74928.1 - 0.00017 21.8 22.5 1.6 9.1 0.1 8.1 5 3 3 8 8 8 2 BolA-like protein zf-C2H2_11 PF16622.5 KFM74928.1 - 0.00098 18.8 106.6 0.045 13.5 0.2 16.6 18 0 0 18 18 18 7 zinc-finger C2H2-type FAM110_N PF14161.6 KFM74928.1 - 0.0017 18.5 0.0 1.7 8.9 0.0 4.1 5 0 0 5 5 5 1 Centrosome-associated N terminus zf-H2C2_5 PF13909.6 KFM74928.1 - 0.0079 15.9 1.6 0.0079 15.9 1.6 18.6 18 2 0 18 18 18 8 C2H2-type zinc-finger domain Complex1_49kDa PF00346.19 KFM74928.1 - 0.019 14.1 2.9 5.6 6.0 0.1 3.8 2 1 2 5 5 5 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit YppF PF14178.6 KFM74928.1 - 0.15 11.9 0.4 48 3.9 0.0 3.3 3 0 0 3 3 3 0 YppF-like protein GAGA PF09237.11 KFM74928.1 - 0.19 11.5 0.1 0.19 11.5 0.1 7.3 6 3 4 10 10 10 0 GAGA factor zf-H2C2_2 PF13465.6 KFM74929.1 - 2.7e-65 214.0 85.5 1.8e-07 31.3 0.9 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM74929.1 - 6.9e-49 161.7 102.7 1.3e-05 25.3 3.7 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM74929.1 - 3.5e-39 130.1 91.6 7.6e-05 23.2 2.5 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM74929.1 - 1.6e-25 88.6 90.3 0.00074 19.8 1.2 11.3 11 0 0 11 11 11 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM74929.1 - 1.1e-17 63.6 78.5 0.0013 18.7 0.3 11.4 11 0 0 11 11 11 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM74929.1 - 4.4e-15 55.5 74.7 0.0019 18.5 2.9 11.1 9 2 2 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM74929.1 - 3.7e-07 29.8 79.9 0.0044 16.8 3.1 12.1 12 1 0 12 12 12 8 C2H2-type zinc-finger domain BolA PF01722.18 KFM74929.1 - 0.00042 20.5 8.3 13 6.2 0.0 5.5 3 2 2 5 5 5 1 BolA-like protein zf-C2H2_11 PF16622.5 KFM74929.1 - 0.019 14.7 0.0 0.019 14.7 0.0 10.0 11 0 0 11 11 11 0 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM74929.1 - 0.036 14.1 1.4 0.036 14.1 1.4 9.2 8 2 3 11 11 11 0 Sec23/Sec24 zinc finger C1_1 PF00130.22 KFM74929.1 - 0.19 11.6 63.9 0.27 11.1 5.7 8.9 3 1 7 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Bromodomain PF00439.25 KFM74930.1 - 3.6e-26 91.0 2.3 6.9e-26 90.1 2.3 1.5 1 0 0 1 1 1 1 Bromodomain MAPKK1_Int PF08923.10 KFM74931.1 - 1.9e-34 118.0 0.1 2.4e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Adeno_Penton_B PF01686.17 KFM74931.1 - 0.084 11.3 0.0 0.099 11.1 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein TGF_beta PF00019.20 KFM74932.1 - 3.5e-31 108.3 0.9 5.9e-31 107.5 0.9 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain PTPRCAP PF15713.5 KFM74932.1 - 0.29 11.4 3.3 0.5 10.6 3.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SIKE PF05769.11 KFM74933.1 - 0.026 14.5 1.6 0.062 13.2 1.6 1.6 1 0 0 1 1 1 0 SIKE family Mating_N PF12731.7 KFM74933.1 - 0.45 10.6 3.1 0.33 11.1 0.2 2.2 2 0 0 2 2 2 0 Mating-type protein beta 1 Cnd1_N PF12922.7 KFM74934.1 - 0.0068 16.3 3.4 0.023 14.5 3.4 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term PseudoU_synth_2 PF00849.22 KFM74935.1 - 0.00016 21.8 0.0 0.00038 20.6 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase Spidroin_N PF16763.5 KFM74936.1 - 1.7e-44 150.9 0.8 1.7e-44 150.9 0.8 2.4 2 1 0 2 2 2 1 Major ampullate spidroin 1, spider silk protein 1, N-term Spidroin_MaSp PF11260.8 KFM74936.1 - 5.4e-28 97.1 18.5 5.4e-28 97.1 18.5 3.3 3 1 0 3 3 3 1 Major ampullate spidroin 1 and 2 MLANA PF14991.6 KFM74937.1 - 0.0077 16.5 0.3 0.013 15.7 0.1 1.6 1 1 1 2 2 2 1 Protein melan-A cNMP_binding PF00027.29 KFM74938.1 - 1.4e-12 47.5 0.0 2.9e-12 46.5 0.0 1.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.10 KFM74939.1 - 3e-25 87.5 0.1 4.7e-25 86.9 0.1 1.3 1 0 0 1 1 1 1 Ion transport protein N-terminal Ion_trans PF00520.31 KFM74939.1 - 1.8e-12 47.0 12.4 5.6e-12 45.4 12.4 1.6 1 1 0 1 1 1 1 Ion transport protein Myosin_head PF00063.21 KFM74941.1 - 1.4e-132 443.3 0.9 1.6e-132 443.1 0.9 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 KFM74941.1 - 0.0065 16.9 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFM74941.1 - 0.018 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KFM74941.1 - 0.02 15.2 0.1 0.045 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFM74941.1 - 0.022 14.0 0.1 0.035 13.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KFM74941.1 - 0.029 14.1 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Microtub_bd PF16796.5 KFM74941.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding AAA_10 PF12846.7 KFM74941.1 - 0.06 12.3 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain SPOB_a PF14689.6 KFM74941.1 - 0.065 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain RNA_helicase PF00910.22 KFM74941.1 - 0.068 13.6 0.0 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 KFM74941.1 - 0.082 13.4 0.6 0.18 12.3 0.3 1.6 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KFM74941.1 - 0.11 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_2 PF03668.15 KFM74941.1 - 0.14 11.5 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family NACHT PF05729.12 KFM74941.1 - 0.15 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Myosin_head PF00063.21 KFM74942.1 - 1.5e-109 367.2 1.5 2e-109 366.8 1.5 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFM74942.1 - 2.2e-50 171.0 1.3 3.7e-50 170.2 1.3 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding PocR PF10114.9 KFM74942.1 - 0.035 13.9 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 Sensory domain found in PocR IQ PF00612.27 KFM74942.1 - 0.18 11.7 4.5 0.52 10.3 4.5 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif 7tm_1 PF00001.21 KFM74943.1 - 4.6e-22 78.6 5.5 6.3e-22 78.1 5.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM74943.1 - 0.0086 15.5 0.2 0.05 13.0 0.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 KFM74944.1 - 3.6e-21 75.7 5.6 5.2e-21 75.2 5.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM74944.1 - 0.00014 21.3 2.9 0.00025 20.5 2.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 KFM74944.1 - 0.11 12.2 8.6 0.15 11.8 8.6 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Wzz PF02706.15 KFM74945.1 - 0.37 11.1 2.1 1.4 9.3 0.1 2.7 2 0 0 2 2 2 0 Chain length determinant protein Abhydro_lipase PF04083.16 KFM74947.1 - 4.9e-24 83.7 0.0 9.4e-24 82.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KFM74947.1 - 1e-21 77.7 0.0 4.4e-21 75.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM74947.1 - 1.1e-09 38.0 0.0 5.1e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM74947.1 - 4.2e-05 24.2 0.0 4.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KFM74947.1 - 0.00089 19.0 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KFM74947.1 - 0.02 13.8 0.0 0.049 12.5 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF3089 PF11288.8 KFM74947.1 - 0.041 13.4 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF900 PF05990.12 KFM74947.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) HH_signal PF01085.18 KFM74948.1 - 7.1e-62 207.8 0.0 7.8e-62 207.7 0.0 1.0 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Peptidase_M15_3 PF08291.11 KFM74948.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 1 0 1 1 1 0 Peptidase M15 Glyco_hydro_38C PF07748.13 KFM74950.1 - 9.1e-41 140.3 0.3 3.6e-40 138.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 KFM74950.1 - 7e-13 48.5 0.2 2.4e-12 46.8 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_38N PF01074.22 KFM74952.1 - 4.4e-86 288.8 11.3 6.2e-86 288.3 11.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 KFM74952.1 - 6.5e-22 77.5 0.0 1.3e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Dimer_Tnp_hAT PF05699.14 KFM74953.1 - 1.1e-06 28.3 0.0 3.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4371 PF14291.6 KFM74953.1 - 2.8e-06 27.2 0.0 2.8e-06 27.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM74953.1 - 0.011 15.3 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type YbfN PF13982.6 KFM74953.1 - 3 8.2 5.4 28 5.1 0.2 3.1 3 0 0 3 3 3 0 YbfN-like lipoprotein PTEN_C2 PF10409.9 KFM74955.1 - 4.6e-31 107.3 0.0 8.7e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein SH2 PF00017.24 KFM74955.1 - 0.00025 21.1 0.0 0.00075 19.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain DDE_3 PF13358.6 KFM74957.1 - 0.00017 21.3 0.0 0.00045 20.0 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease DUF5580 PF17743.1 KFM74959.1 - 0.023 13.3 0.6 0.032 12.8 0.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5580) Vps52 PF04129.12 KFM74959.1 - 0.029 13.1 0.2 0.042 12.6 0.2 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family HTH_28 PF13518.6 KFM74960.1 - 0.16 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.6 KFM74961.1 - 3.4e-06 26.9 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PRANC PF09372.10 KFM74961.1 - 0.029 14.7 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Ras PF00071.22 KFM74962.1 - 1.9e-62 209.6 0.2 2.3e-62 209.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM74962.1 - 7.5e-36 123.0 0.0 1.2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM74962.1 - 6.5e-13 48.5 0.0 8.2e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM74962.1 - 4.1e-05 23.0 0.0 5.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM74962.1 - 9.6e-05 22.4 0.0 0.00016 21.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM74962.1 - 0.00011 22.1 0.2 0.37 10.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFM74962.1 - 0.00088 18.9 0.1 0.0022 17.6 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFM74962.1 - 0.0099 16.3 0.2 0.018 15.5 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain MCR_beta PF02241.18 KFM74962.1 - 0.048 13.3 0.2 0.061 12.9 0.2 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain AAA_22 PF13401.6 KFM74962.1 - 0.11 12.8 0.0 1.2 9.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 KFM74962.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit bZIP_1 PF00170.21 KFM74963.1 - 1.2e-16 60.6 15.0 2.1e-16 59.8 15.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM74963.1 - 6e-07 29.5 9.9 6e-07 29.5 9.9 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFM74963.1 - 7.1e-07 29.7 8.0 1.3e-06 28.8 8.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor APG6_N PF17675.1 KFM74963.1 - 0.0033 18.0 4.3 0.0066 17.0 4.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF3450 PF11932.8 KFM74963.1 - 0.032 13.5 1.5 0.053 12.8 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 KFM74963.1 - 0.038 14.2 5.4 0.067 13.4 5.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 KFM74963.1 - 0.045 13.8 8.1 0.081 13.0 8.1 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 KFM74963.1 - 0.081 13.4 2.8 0.15 12.6 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF724 PF05266.14 KFM74963.1 - 1.4 8.7 8.0 2.4 7.9 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KFM74963.1 - 4 5.2 5.4 5.5 4.8 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4404 PF14357.6 KFM74963.1 - 4.5 8.0 6.5 0.66 10.7 1.1 2.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4404) HTH_Tnp_Tc5 PF03221.16 KFM74964.1 - 0.035 14.2 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain NAD_binding_2 PF03446.15 KFM74965.1 - 6.8e-35 120.6 0.0 1.8e-34 119.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PWWP PF00855.17 KFM74965.1 - 7.5e-19 67.9 0.2 2.1e-18 66.5 0.2 1.8 1 0 0 1 1 1 1 PWWP domain NAD_binding_11 PF14833.6 KFM74965.1 - 1.4e-17 64.0 0.0 2.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFM74965.1 - 3.4e-08 33.9 0.0 1.2e-07 32.2 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KFM74965.1 - 1.5e-05 25.0 0.1 4.9e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KFM74965.1 - 0.00027 20.3 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KFM74965.1 - 0.00078 19.4 0.1 0.00078 19.4 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KFM74965.1 - 0.0018 17.9 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 KFM74965.1 - 0.0095 15.5 0.1 0.034 13.7 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rotamase_2 PF13145.6 KFM74965.1 - 0.013 16.3 1.1 0.028 15.3 1.1 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain Sacchrp_dh_NADP PF03435.18 KFM74965.1 - 0.022 15.0 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KFM74965.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding NAD_Gly3P_dh_N PF01210.23 KFM74965.1 - 0.079 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KFM74966.1 - 6.6e-35 120.6 0.0 2e-34 119.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFM74966.1 - 2e-19 70.0 0.2 3.7e-19 69.2 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.17 KFM74966.1 - 2e-18 66.5 0.2 2e-18 66.5 0.2 2.0 2 0 0 2 2 2 1 PWWP domain F420_oxidored PF03807.17 KFM74966.1 - 2.3e-09 37.7 0.0 9.9e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KFM74966.1 - 2e-05 24.6 0.0 6.4e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KFM74966.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFM74966.1 - 0.00017 21.2 0.0 0.00035 20.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KFM74966.1 - 0.0013 18.7 0.1 0.0013 18.7 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 KFM74966.1 - 0.0025 17.4 0.1 0.0074 15.9 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 KFM74966.1 - 0.26 11.5 0.9 0.74 10.1 0.0 2.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain DUF4554 PF15091.6 KFM74966.1 - 0.27 10.1 5.8 0.39 9.5 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) NAD_Gly3P_dh_N PF01210.23 KFM74966.1 - 0.35 10.8 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GREB1 PF15782.5 KFM74966.1 - 3.3 4.7 7.9 4.2 4.4 7.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer 2OG-FeII_Oxy_2 PF13532.6 KFM74967.1 - 6.4e-15 55.8 0.0 1.3e-13 51.6 0.0 2.0 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily DDE_3 PF13358.6 KFM74968.1 - 3.4e-16 59.3 0.1 3.5e-15 56.0 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74968.1 - 1.5e-10 41.2 1.0 2.9e-10 40.2 1.0 1.5 1 0 0 1 1 1 1 Transposase Erg28 PF03694.13 KFM74969.1 - 3.7e-09 37.0 2.9 4.8e-09 36.6 2.9 1.2 1 0 0 1 1 1 1 Erg28 like protein Glyco_transf_29 PF00777.18 KFM74970.1 - 0.0019 17.7 0.2 0.0029 17.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF2344 PF10105.9 KFM74970.1 - 0.015 15.2 3.0 0.052 13.4 1.4 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2344) Arch_fla_DE PF04659.13 KFM74970.1 - 0.02 14.7 0.4 6.4 6.7 0.1 2.7 2 1 1 3 3 3 0 Archaeal flagella protein PAH PF02671.21 KFM74970.1 - 0.11 12.7 0.4 0.62 10.3 0.1 2.2 2 0 0 2 2 2 0 Paired amphipathic helix repeat Arch_fla_DE PF04659.13 KFM74971.1 - 0.076 12.9 0.1 1.2 9.1 0.0 2.4 1 1 1 2 2 2 0 Archaeal flagella protein KH_dom-like PF14714.6 KFM74971.1 - 0.17 12.2 2.5 2 8.8 0.4 3.4 3 0 0 3 3 3 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal zf-CCHC_4 PF14392.6 KFM74971.1 - 0.18 11.6 1.4 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFM74974.1 - 0.25 11.1 3.3 0.17 11.6 1.2 1.8 2 0 0 2 2 2 0 Zinc knuckle efThoc1 PF11957.8 KFM74975.1 - 2.2e-53 181.6 5.2 2.2e-53 181.6 5.2 2.0 1 1 1 2 2 2 1 THO complex subunit 1 transcription elongation factor Death PF00531.22 KFM74975.1 - 5.3e-08 32.9 0.2 1.5e-07 31.5 0.2 1.8 1 0 0 1 1 1 1 Death domain efThoc1 PF11957.8 KFM74976.1 - 1.3e-41 142.8 2.5 2e-41 142.2 2.5 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor RHH_6 PF16762.5 KFM74976.1 - 0.19 12.4 0.3 0.37 11.4 0.3 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain SRP54 PF00448.22 KFM74977.1 - 8.5e-78 260.5 0.5 1.5e-77 259.7 0.1 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KFM74977.1 - 9e-29 100.0 2.8 9e-29 100.0 2.8 3.2 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 KFM74977.1 - 1e-19 70.5 2.5 3.6e-19 68.7 2.5 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 KFM74977.1 - 6.5e-06 26.4 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KFM74977.1 - 8.2e-05 22.1 0.4 0.28 10.6 0.0 2.6 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit AAA_17 PF13207.6 KFM74977.1 - 0.00013 22.4 0.0 0.00046 20.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFM74977.1 - 0.00045 20.3 0.2 0.0014 18.7 0.2 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit cobW PF02492.19 KFM74977.1 - 0.00055 19.6 1.8 0.015 14.9 2.0 2.5 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KFM74977.1 - 0.00077 19.9 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KFM74977.1 - 0.001 19.1 0.0 0.0047 17.0 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KFM74977.1 - 0.0038 16.5 0.0 0.0073 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.23 KFM74977.1 - 0.0039 17.3 0.1 0.025 14.6 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KFM74977.1 - 0.0044 16.1 0.2 0.056 12.4 0.0 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KFM74977.1 - 0.0046 16.9 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 KFM74977.1 - 0.0047 17.2 1.2 0.094 13.0 0.1 2.9 1 1 1 2 2 2 1 AAA domain CLP1_P PF16575.5 KFM74977.1 - 0.0071 16.2 0.4 4.5 7.0 0.1 2.4 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA PF00004.29 KFM74977.1 - 0.013 15.9 4.2 0.25 11.8 0.1 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF2209 PF09974.9 KFM74977.1 - 0.013 15.8 0.1 0.038 14.3 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) AAA_31 PF13614.6 KFM74977.1 - 0.015 15.2 0.1 0.055 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFM74977.1 - 0.019 15.5 0.1 0.063 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFM74977.1 - 0.025 14.3 0.0 0.074 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM74977.1 - 0.038 14.2 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFM74977.1 - 0.041 13.6 0.3 0.56 10.0 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 KFM74977.1 - 0.048 13.6 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.18 KFM74977.1 - 0.063 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_25 PF13481.6 KFM74977.1 - 0.072 12.7 0.2 0.19 11.3 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFM74977.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KFM74977.1 - 0.078 12.7 0.9 0.29 10.9 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KFM74977.1 - 0.098 12.4 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DNA_pol3_chi PF04364.13 KFM74977.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC Torsin PF06309.11 KFM74977.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Torsin G-alpha PF00503.20 KFM74977.1 - 0.19 10.9 0.9 4.3 6.4 0.1 2.9 2 1 0 3 3 3 0 G-protein alpha subunit ArsA_ATPase PF02374.15 KFM74977.1 - 0.22 10.7 0.0 0.22 10.7 0.0 2.8 4 0 0 4 4 4 0 Anion-transporting ATPase LRR_4 PF12799.7 KFM74978.1 - 0.00055 20.3 3.1 0.037 14.4 0.3 2.4 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM74978.1 - 0.0031 17.8 6.1 2.5 9.0 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 KFM74978.1 - 2.2 8.6 3.7 6.4 7.1 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeat NUDIX PF00293.28 KFM74979.1 - 0.00012 22.1 0.0 0.00031 20.8 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Kinesin PF00225.23 KFM74982.1 - 1e-05 24.7 0.0 1.4e-05 24.2 0.0 1.2 1 1 0 1 1 1 1 Kinesin motor domain Rax2 PF12768.7 KFM74982.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Kinesin PF00225.23 KFM74983.1 - 4.4e-06 25.8 0.0 4.5e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain DDE_3 PF13358.6 KFM74985.1 - 4.4e-10 39.5 0.0 5.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM74986.1 - 1.3e-11 44.4 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74987.1 - 2.7e-14 53.2 1.0 5.5e-14 52.2 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74987.1 - 7.1e-14 51.8 0.0 9.3e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM74988.1 - 5.8e-11 42.3 0.0 8.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74988.1 - 6.5e-06 26.3 0.3 1.3e-05 25.3 0.3 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM74989.1 - 1.3e-11 44.6 1.7 2.2e-11 43.8 1.7 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM74989.1 - 4.7e-07 29.7 0.0 7.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM74990.1 - 5e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM74990.1 - 1.3e-13 50.9 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM74990.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM74990.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM74990.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain Rap_GAP PF02145.15 KFM74993.1 - 7e-28 97.4 0.1 7.6e-28 97.3 0.1 1.0 1 0 0 1 1 1 1 Rap/ran-GAP Rap_GAP PF02145.15 KFM74994.1 - 3.4e-19 69.1 0.2 5.1e-19 68.5 0.2 1.3 1 0 0 1 1 1 1 Rap/ran-GAP GAS PF13851.6 KFM74994.1 - 0.045 13.1 4.8 0.073 12.4 4.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 KFM74994.1 - 1.3 9.3 3.7 2.7 8.3 3.7 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TMEM51 PF15345.6 KFM74996.1 - 0.0042 17.0 0.0 0.0046 16.8 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 DUF2207 PF09972.9 KFM74996.1 - 0.017 13.9 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Insulin_TMD PF17870.1 KFM74996.1 - 0.032 14.3 1.4 0.061 13.4 1.4 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 KFM74996.1 - 0.034 15.0 0.0 0.062 14.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4446 PF14584.6 KFM74996.1 - 0.035 14.1 0.1 0.046 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Integrin_alpha PF00357.20 KFM74996.1 - 0.06 13.3 6.3 0.12 12.4 6.3 1.5 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region DUF4834 PF16118.5 KFM74996.1 - 0.062 14.3 0.1 0.098 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) LYRIC PF15686.5 KFM74996.1 - 0.077 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Cytadhesin_P30 PF07271.11 KFM74996.1 - 0.085 12.4 0.0 0.094 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 FAM176 PF14851.6 KFM74996.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Ly49 PF08391.10 KFM74996.1 - 0.13 12.6 0.1 0.19 12.1 0.1 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region MLANA PF14991.6 KFM74996.1 - 0.17 12.2 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Integrin_alpha2 PF08441.12 KFM74997.1 - 6.9e-44 150.5 0.2 8.6e-44 150.2 0.2 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFM74997.1 - 9e-16 57.7 24.1 5.1e-08 32.9 3.8 4.9 6 0 0 6 6 6 2 FG-GAP repeat FG-GAP_2 PF14312.6 KFM74997.1 - 1e-11 44.9 10.8 0.039 14.2 0.1 5.5 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.6 KFM74997.1 - 7.7e-09 36.0 7.1 1.8e-05 25.2 1.6 3.4 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HisK_sensor PF18698.1 KFM74997.1 - 0.00021 21.7 0.6 3.8 7.9 0.0 3.5 3 0 0 3 3 3 2 Histidine kinase sensor domain Grp7_allergen PF16984.5 KFM74998.1 - 2.4e-18 66.8 0.6 2.1e-17 63.8 0.6 1.9 1 1 0 1 1 1 1 Group 7 allergen JHBP PF06585.11 KFM74998.1 - 0.0089 15.2 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) Grp7_allergen PF16984.5 KFM74999.1 - 0.0015 18.6 0.4 0.0016 18.5 0.4 1.0 1 0 0 1 1 1 1 Group 7 allergen SpoVIF PF14069.6 KFM74999.1 - 0.031 14.0 0.8 0.051 13.4 0.8 1.3 1 0 0 1 1 1 0 Stage VI sporulation protein F Orthopox_A47 PF06334.11 KFM74999.1 - 0.036 13.3 0.2 0.043 13.1 0.2 1.1 1 0 0 1 1 1 0 Orthopoxvirus A47 protein Grp7_allergen PF16984.5 KFM75000.1 - 1.5e-06 28.4 0.6 1.2e-05 25.4 0.6 2.0 1 1 0 1 1 1 1 Group 7 allergen MRP-S28 PF10213.9 KFM75001.1 - 4.1e-17 62.8 0.1 7.7e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein IncE PF17627.2 KFM75002.1 - 0.053 13.5 0.6 0.058 13.4 0.6 1.0 1 0 0 1 1 1 0 Inclusion membrane protein E PTN_MK_C PF01091.18 KFM75003.1 - 5.5e-40 135.6 30.8 1.4e-14 54.2 5.8 3.1 1 1 2 3 3 3 3 PTN/MK heparin-binding protein family, C-terminal domain YBD PF17725.1 KFM75004.1 - 1.2e-54 185.4 3.3 1.3e-54 185.2 3.3 1.0 1 0 0 1 1 1 1 YAP binding domain YBD PF17725.1 KFM75005.1 - 5.1e-33 114.7 0.0 7.8e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KFM75005.1 - 4.9e-14 52.2 0.9 9.7e-14 51.2 0.9 1.5 1 0 0 1 1 1 1 TEA/ATTS domain Miga PF10265.9 KFM75005.1 - 0.14 11.1 5.0 0.18 10.7 5.0 1.1 1 0 0 1 1 1 0 Mitoguardin DUF3578 PF12102.8 KFM75005.1 - 0.16 11.5 1.1 0.24 10.9 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3578) DIL PF01843.19 KFM75005.1 - 1.9 8.8 4.8 7.6 6.9 4.8 2.0 1 1 0 1 1 1 0 DIL domain DDE_3 PF13358.6 KFM75006.1 - 1.5e-14 54.0 0.0 2.1e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1758 PF05585.12 KFM75007.1 - 5e-07 29.6 0.1 2.6e-06 27.3 0.1 2.0 2 0 0 2 2 2 1 Putative peptidase (DUF1758) PIF1 PF05970.14 KFM75008.1 - 7.6e-22 78.0 2.6 3.5e-18 65.9 0.3 2.0 1 1 1 2 2 2 2 PIF1-like helicase MIF4G PF02854.19 KFM75009.1 - 1.3e-18 67.4 1.3 1.7e-18 67.0 1.3 1.1 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 KFM75009.1 - 0.00053 19.5 1.8 0.0032 17.1 0.2 2.5 2 0 0 2 2 2 1 Ataxin-2 C-terminal region zf-C2H2_4 PF13894.6 KFM75010.1 - 2.9e-19 68.1 144.2 0.011 16.5 1.0 16.0 16 0 0 16 16 16 14 C2H2-type zinc finger zf-CRD PF17979.1 KFM75010.1 - 1.4e-14 54.5 45.2 0.0004 20.5 0.0 9.7 10 1 1 11 11 11 7 Cysteine rich domain with multizinc binding regions zf-C2H2 PF00096.26 KFM75010.1 - 5.2e-13 48.7 148.6 0.057 13.9 3.8 15.7 15 0 0 15 15 15 13 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KFM75010.1 - 0.0011 19.2 0.9 0.0011 19.2 0.9 12.5 11 3 3 14 14 14 5 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFM75010.1 - 0.13 13.0 60.6 0.66 10.7 1.6 12.7 10 3 3 13 13 13 0 Zinc finger C2H2-type, 3 repeats Trm112p PF03966.16 KFM75010.1 - 0.3 11.7 1.8 28 5.4 0.0 3.5 3 0 0 3 3 3 0 Trm112p-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM75012.1 - 2.5e-16 59.7 2.8 5.1e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75012.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75012.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75012.1 - 0.0023 17.7 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75012.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain CAAP1 PF15335.6 KFM75013.1 - 3.4e-15 56.3 0.8 5.4e-15 55.7 0.8 1.3 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 Tnp_P_element PF12017.8 KFM75014.1 - 4.6e-13 49.1 0.4 1e-12 48.0 0.4 1.6 1 0 0 1 1 1 1 Transposase protein DDE_3 PF13358.6 KFM75015.1 - 2e-05 24.4 0.0 2.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zinc_ribbon_4 PF13717.6 KFM75016.1 - 0.02 14.8 0.9 0.037 13.9 0.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain CTD_bind PF04818.13 KFM75018.1 - 0.009 16.8 0.3 0.064 14.1 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase II-binding domain. bPH_4 PF06713.11 KFM75018.1 - 0.084 13.0 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial PH domain zf-H2C2_2 PF13465.6 KFM75019.1 - 3.5e-99 321.2 96.2 2.5e-09 37.1 0.4 14.4 14 1 0 14 14 14 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75019.1 - 6.7e-64 209.0 116.7 3.9e-06 27.0 1.4 13.9 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75019.1 - 9.5e-42 138.0 112.4 0.0019 18.9 0.8 13.7 14 0 0 14 14 14 12 C2H2-type zinc finger zf-met PF12874.7 KFM75019.1 - 8.8e-38 127.6 106.3 0.0012 19.2 0.8 14.2 14 0 0 14 14 14 13 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM75019.1 - 2.3e-23 81.7 103.2 0.00022 21.2 2.9 15.2 14 2 0 14 14 14 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75019.1 - 5.9e-16 58.3 80.2 0.18 12.1 0.2 14.0 13 1 1 14 14 14 9 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM75019.1 - 1.5e-10 40.6 74.3 0.037 13.8 0.0 12.3 13 0 0 13 13 11 8 C2H2-type zinc-finger domain DUF2256 PF10013.9 KFM75019.1 - 1.2e-09 38.1 39.4 6.9 6.9 0.1 12.9 14 0 0 14 14 13 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM75019.1 - 2.8e-08 33.6 43.2 0.31 11.0 0.7 8.5 5 3 5 10 10 9 7 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM75019.1 - 3.6e-06 27.0 13.8 0.34 11.1 0.0 6.7 1 1 8 9 9 9 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-CHCC PF10276.9 KFM75019.1 - 2.1e-05 24.5 16.3 1.4e+02 2.6 0.0 11.0 12 0 0 12 12 12 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KFM75019.1 - 9e-05 22.3 50.3 8.4 6.4 0.1 12.9 14 0 0 14 14 13 0 zinc-finger of a C2HC-type GAGA PF09237.11 KFM75019.1 - 0.00016 21.4 22.6 0.099 12.5 0.2 7.6 4 3 5 9 9 8 2 GAGA factor FYVE PF01363.21 KFM75019.1 - 0.00037 20.6 68.7 0.092 12.9 15.5 6.7 1 1 6 7 7 7 5 FYVE zinc finger zf-C2H2_9 PF16293.5 KFM75019.1 - 0.00078 19.2 51.9 1.9 8.4 0.2 11.8 3 2 9 12 12 12 1 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM75019.1 - 0.0067 16.7 29.2 1.3 9.4 0.2 6.7 1 1 6 7 7 7 2 BolA-like protein Peptidase_M15_2 PF05951.13 KFM75019.1 - 0.016 14.9 1.1 4 7.1 0.0 4.1 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF882) zinc_ribbon_15 PF17032.5 KFM75019.1 - 0.016 15.9 51.6 3.2 8.6 4.3 6.7 1 1 6 8 8 8 0 zinc-ribbon family DUF3396 PF11876.8 KFM75019.1 - 0.021 14.3 0.0 12 5.3 0.0 4.1 2 2 4 6 6 6 0 Protein of unknown function (DUF3396) zf-C2H2_11 PF16622.5 KFM75019.1 - 0.021 14.6 69.9 1.1 9.1 0.2 12.7 13 0 0 13 13 13 0 zinc-finger C2H2-type eRF1_2 PF03464.15 KFM75019.1 - 0.042 14.2 5.1 4.5 7.6 0.1 4.2 3 1 0 4 4 4 0 eRF1 domain 2 zf-RRPl_C4 PF17026.5 KFM75019.1 - 0.069 13.3 51.1 0.15 12.2 5.0 5.8 1 1 3 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_2 PF12756.7 KFM75019.1 - 0.08 13.3 84.4 2 8.8 1.7 11.8 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFM75019.1 - 0.25 11.3 69.5 7.3 6.6 7.4 11.1 3 1 9 12 12 12 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PqqA PF08042.11 KFM75019.1 - 0.25 11.4 3.5 6.5e+02 0.6 0.0 6.2 7 0 0 7 7 7 0 PqqA family zf-Dof PF02701.15 KFM75019.1 - 0.39 10.9 38.2 3.3 7.9 0.7 9.1 1 1 7 9 9 8 0 Dof domain, zinc finger zf-MYST PF17772.1 KFM75019.1 - 1.5 8.5 57.0 6.9 6.4 0.5 11.9 5 4 7 12 12 12 0 MYST family zinc finger domain HNH_5 PF14279.6 KFM75019.1 - 2 8.3 65.0 1.3 8.9 1.0 11.5 4 3 6 11 11 11 0 HNH endonuclease C5HCH PF17982.1 KFM75019.1 - 3.1 8.0 61.7 31 4.8 2.2 12.4 8 2 4 13 13 13 0 NSD Cys-His rich domain zf-Sec23_Sec24 PF04810.15 KFM75019.1 - 5.9 7.0 53.1 0.16 12.1 1.8 11.2 9 3 3 12 12 12 0 Sec23/Sec24 zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM75020.1 - 2.7e-16 59.6 2.8 4.8e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75020.1 - 1.6e-13 50.6 0.0 2.8e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75020.1 - 3e-07 30.1 0.7 6.2e-07 29.1 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75020.1 - 0.0023 17.7 0.6 0.0066 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75020.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc5 PF03221.16 KFM75021.1 - 0.00012 22.0 0.1 0.00026 21.0 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain TIMELESS PF04821.14 KFM75022.1 - 8.4e-13 48.2 0.0 1.6e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Timeless protein Secretin_N_2 PF07655.13 KFM75022.1 - 2.1 8.9 19.6 1.8 9.1 6.7 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Neur_chan_memb PF02932.16 KFM75024.1 - 0.29 11.2 3.3 0.34 10.9 3.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1759 PF03564.15 KFM75025.1 - 4.9e-34 117.4 4.0 5.1e-32 110.9 0.2 3.0 4 0 0 4 4 4 2 Protein of unknown function (DUF1759) DUF5641 PF18701.1 KFM75025.1 - 2.7e-32 110.8 1.1 6.9e-32 109.5 1.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 KFM75025.1 - 1.7e-09 37.9 0.0 4.5e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM75025.1 - 0.013 15.6 2.2 0.013 15.6 2.2 2.3 2 0 0 2 2 2 0 Integrase zinc binding domain Hemocyanin_M PF00372.19 KFM75026.1 - 0.042 13.0 0.2 0.048 12.8 0.2 1.1 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Histone PF00125.24 KFM75027.1 - 6.6e-24 84.7 2.0 7.9e-24 84.5 2.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM75027.1 - 5.6e-06 26.5 0.1 5.6e-06 26.5 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFM75027.1 - 0.0011 19.4 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFM75027.1 - 0.0042 17.2 1.0 0.005 16.9 1.0 1.2 1 0 0 1 1 1 1 YscO-like protein TIMELESS_C PF05029.13 KFM75028.1 - 0.0017 17.6 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 Timeless protein C terminal region Elong-fact-P_C PF09285.11 KFM75028.1 - 0.062 13.1 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Elongation factor P, C-terminal HTH_Tnp_Tc3_2 PF01498.18 KFM75029.1 - 1.4e-18 66.9 2.3 1.8e-18 66.5 2.3 1.2 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM75029.1 - 0.0016 19.0 1.4 0.0016 19.0 1.4 1.7 2 0 0 2 2 2 1 Homeodomain-like domain Sec23_trunk PF04811.15 KFM75031.1 - 4.6e-87 291.6 0.0 7.3e-87 291.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFM75031.1 - 2.2e-24 85.3 0.1 3.8e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFM75031.1 - 6.6e-19 68.5 0.0 1.5e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFM75031.1 - 2.5e-15 56.2 1.9 9.5e-15 54.4 1.9 2.1 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFM75031.1 - 4.1e-08 33.0 0.0 9.1e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat VWA PF00092.28 KFM75031.1 - 0.059 13.6 0.4 0.12 12.7 0.4 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain ABA_GPCR PF12430.8 KFM75033.1 - 0.059 13.1 0.0 0.067 12.9 0.0 1.0 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor DDE_3 PF13358.6 KFM75033.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease p450 PF00067.22 KFM75034.1 - 5.5e-109 365.0 0.1 6.2e-109 364.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 QVR PF17064.5 KFM75035.1 - 7.3e-06 26.1 6.3 1e-05 25.7 6.3 1.2 1 0 0 1 1 1 1 Sleepless protein PQ-loop PF04193.14 KFM75038.1 - 3.9e-15 55.4 1.2 3.9e-15 55.4 1.2 2.0 2 1 1 3 3 3 1 PQ loop repeat TFIIA_gamma_N PF02268.16 KFM75039.1 - 0.045 13.8 0.2 0.065 13.3 0.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain ABC2_membrane PF01061.24 KFM75039.1 - 0.049 13.0 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 ABC-2 type transporter ABC2_membrane PF01061.24 KFM75040.1 - 2.8e-17 62.9 19.7 2.8e-17 62.9 19.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KFM75040.1 - 5e-07 29.1 25.6 6.2e-07 28.8 25.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Ank_2 PF12796.7 KFM75041.1 - 2e-39 134.1 13.1 2.6e-14 53.6 0.5 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM75041.1 - 1e-37 128.0 6.4 2.8e-09 37.3 0.4 7.6 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM75041.1 - 2.5e-29 98.1 7.8 0.00072 19.8 0.0 9.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFM75041.1 - 4.3e-27 93.8 15.5 4.6e-10 39.6 0.1 6.7 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KFM75041.1 - 6.2e-27 92.8 10.7 3.2e-05 24.2 0.1 8.6 9 0 0 9 9 9 6 Ankyrin repeat TBP PF00352.21 KFM75044.1 - 6.5e-49 163.8 0.1 2e-25 88.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) H_lectin PF09458.10 KFM75044.1 - 0.11 12.7 0.1 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 H-type lectin domain zf-C2H2_4 PF13894.6 KFM75045.1 - 0.063 14.2 1.4 0.17 12.8 1.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 KFM75046.1 - 0.00038 20.7 3.0 0.00038 20.7 3.0 2.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-SNAP50_C PF12251.8 KFM75046.1 - 0.0012 18.6 6.1 0.0012 18.6 6.1 1.0 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C2H2_4 PF13894.6 KFM75046.1 - 0.0028 18.4 15.4 0.0095 16.7 3.9 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM75046.1 - 0.08 13.4 3.9 0.08 13.4 3.9 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ras PF00071.22 KFM75047.1 - 9.5e-66 220.4 0.2 1.1e-65 220.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM75047.1 - 4e-35 120.6 0.2 7.8e-35 119.7 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM75047.1 - 2e-16 59.9 0.2 2.6e-16 59.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM75047.1 - 1.5e-06 27.8 0.2 1.8e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM75047.1 - 5.7e-06 25.9 0.1 8.5e-06 25.3 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFM75047.1 - 0.00034 20.5 0.1 0.39 10.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFM75047.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFM75047.1 - 0.0046 16.5 0.1 0.011 15.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFM75047.1 - 0.011 15.6 0.1 0.039 13.7 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Phage_holin_6_1 PF09682.10 KFM75047.1 - 0.039 14.4 0.1 0.064 13.7 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Efg1 PF10153.9 KFM75047.1 - 0.04 14.3 0.6 0.055 13.8 0.6 1.2 1 0 0 1 1 1 0 rRNA-processing protein Efg1 PduV-EutP PF10662.9 KFM75047.1 - 0.071 12.9 0.2 0.13 12.0 0.2 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KFM75047.1 - 0.08 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF3963 PF13124.6 KFM75047.1 - 0.16 11.9 0.3 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) AAA_16 PF13191.6 KFM75047.1 - 0.17 12.2 0.1 0.4 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF4111 PF13427.6 KFM75048.1 - 0.0068 16.5 0.0 0.0086 16.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) RT_RNaseH_2 PF17919.1 KFM75049.1 - 9.6e-31 105.8 0.0 4.9e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM75049.1 - 2.8e-29 101.5 0.0 1.4e-28 99.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM75049.1 - 2.1e-28 99.4 0.1 5.7e-28 98.0 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM75049.1 - 2e-18 66.7 0.0 3.6e-17 62.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM75049.1 - 2.1e-16 59.7 0.0 7.8e-16 57.9 0.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain Arc_C PF18162.1 KFM75049.1 - 3.7e-05 23.5 1.7 0.00013 21.7 0.4 2.7 3 0 0 3 3 3 1 Arc C-lobe zf-H2C2 PF09337.10 KFM75049.1 - 0.0013 18.9 0.0 0.004 17.3 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 KFM75049.1 - 0.021 15.1 2.8 0.23 11.7 0.0 3.7 3 0 0 3 3 3 0 Retrotransposon gag protein NCD3G PF07562.14 KFM75050.1 - 0.011 15.6 1.5 0.011 15.6 1.5 2.7 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Jiv90 PF14901.6 KFM75050.1 - 1.7 8.9 8.0 0.4 10.9 2.7 2.4 1 1 0 2 2 2 0 Cleavage inducing molecular chaperone zf-CCHC_3 PF13917.6 KFM75050.1 - 5.8 7.0 13.1 1.3 9.1 6.1 2.5 1 1 1 2 2 2 0 Zinc knuckle 6PF2K PF01591.18 KFM75051.1 - 5.2e-81 271.2 5.0 2.6e-51 174.1 2.4 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFM75051.1 - 9.5e-31 107.0 1.1 2.2e-27 96.0 0.8 2.8 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Transposase_1 PF01359.18 KFM75051.1 - 5.4e-15 55.0 0.0 1.1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) AAA_33 PF13671.6 KFM75051.1 - 0.00057 20.1 0.0 0.0019 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain HTH_40 PF14493.6 KFM75051.1 - 0.55 10.7 2.1 6.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain CdvA PF18822.1 KFM75051.1 - 1.1 9.1 3.3 16 5.3 0.1 3.1 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Sacchrp_dh_C PF16653.5 KFM75052.1 - 7.4e-87 291.8 0.0 2.1e-86 290.3 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 KFM75052.1 - 6.9e-28 97.6 0.2 1.1e-26 93.7 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 KFM75052.1 - 1.2e-21 77.4 0.3 3.6e-21 75.8 0.2 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KFM75052.1 - 4.1e-05 23.0 0.0 0.00096 18.5 0.0 3.0 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFM75052.1 - 0.069 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KFM75053.1 - 1.3e-07 31.5 0.3 1.4e-07 31.5 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFM75053.1 - 0.00049 19.4 0.0 0.00049 19.4 0.0 1.0 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KFM75053.1 - 0.0035 16.5 0.2 0.0039 16.3 0.2 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFM75053.1 - 0.0065 15.7 0.1 0.0065 15.7 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM75053.1 - 0.01 16.0 0.1 0.012 15.9 0.1 1.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KFM75053.1 - 0.027 13.0 0.0 0.027 13.0 0.0 1.0 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 KFM75053.1 - 0.029 14.4 0.2 0.03 14.3 0.2 1.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFM75053.1 - 0.067 13.8 0.2 0.067 13.8 0.2 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM75053.1 - 0.11 11.7 0.2 0.11 11.7 0.2 1.0 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KFM75053.1 - 0.13 11.1 0.1 0.14 11.0 0.1 1.0 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 KFM75053.1 - 0.19 11.1 0.2 0.19 11.1 0.2 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 KFM75054.1 - 1.4e-12 47.8 0.0 1.9e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1997 PF09366.10 KFM75054.1 - 0.02 15.0 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1997) LRR_6 PF13516.6 KFM75055.1 - 0.02 14.9 0.7 1.2 9.4 0.1 2.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KFM75055.1 - 0.048 14.2 0.3 2.5 9.0 0.0 2.6 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.6 KFM75056.1 - 1.5e-08 34.3 0.3 1.5e-08 34.3 0.3 1.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 KFM75056.1 - 0.0023 17.5 0.1 0.0028 17.2 0.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFM75056.1 - 0.016 15.6 2.3 0.21 12.1 2.5 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM75056.1 - 0.051 13.5 0.1 0.071 13.1 0.1 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) DDE_Tnp_1_7 PF13843.6 KFM75059.1 - 1e-22 80.9 0.1 1.3e-22 80.7 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 zf-C2H2_12 PF18658.1 KFM75060.1 - 0.0082 15.7 0.8 0.013 15.1 0.8 1.4 1 1 0 1 1 1 1 Zinc-finger C2H2-type zf-BED PF02892.15 KFM75060.1 - 0.024 14.7 0.6 0.04 13.9 0.6 1.4 1 0 0 1 1 1 0 BED zinc finger DHHC PF01529.20 KFM75062.1 - 6.9e-25 87.7 11.0 6.9e-25 87.7 11.0 3.1 2 1 1 3 3 3 1 DHHC palmitoyltransferase Pox_F15 PF04596.12 KFM75062.1 - 0.016 15.0 0.6 0.028 14.2 0.6 1.4 1 0 0 1 1 1 0 Poxvirus protein F15 PspB PF06667.12 KFM75062.1 - 1.1 9.3 3.8 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Phage shock protein B HEAT PF02985.22 KFM75065.1 - 1e-43 143.6 28.7 5.5e-05 23.1 0.1 11.2 11 0 0 11 11 11 11 HEAT repeat HEAT_2 PF13646.6 KFM75065.1 - 3.9e-33 113.7 2.6 3.5e-13 49.8 0.0 6.3 2 2 3 5 5 5 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KFM75065.1 - 2.8e-14 53.5 2.8 0.014 16.0 0.0 7.2 1 1 7 8 8 8 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFM75065.1 - 4.2e-12 46.3 9.2 0.0027 18.2 0.0 6.3 7 1 0 7 7 6 4 HEAT-like repeat Cnd1 PF12717.7 KFM75065.1 - 4.3e-08 33.4 7.1 0.014 15.4 0.3 4.0 1 1 2 4 4 4 4 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KFM75065.1 - 9e-08 32.0 1.2 0.032 13.8 0.0 3.9 1 1 1 3 3 3 3 CLASP N terminal TAF6_C PF07571.13 KFM75065.1 - 1.2e-05 25.6 0.0 0.78 10.1 0.0 4.4 2 2 1 3 3 3 2 TAF6 C-terminal HEAT repeat domain Adaptin_N PF01602.20 KFM75065.1 - 1.5e-05 23.8 5.8 0.011 14.4 2.9 3.0 1 1 1 3 3 3 3 Adaptin N terminal region M11L PF11099.8 KFM75065.1 - 0.00024 21.4 0.1 0.0016 18.7 0.0 2.3 2 1 1 3 3 3 1 Apoptosis regulator M11L like DRIM PF07539.12 KFM75065.1 - 0.012 14.0 0.4 0.095 11.0 0.4 2.0 1 1 0 1 1 1 0 Down-regulated in metastasis IFRD PF05004.13 KFM75065.1 - 0.049 12.7 0.8 2.8 7.0 0.2 3.2 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) NPA PF16469.5 KFM75065.1 - 0.1 13.2 0.1 20 5.8 0.1 3.1 2 1 1 3 3 3 0 Nematode polyprotein allergen ABA-1 RasGEF_N_2 PF14663.6 KFM75065.1 - 0.18 12.2 2.6 22 5.5 0.1 4.0 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain YwqJ-deaminase PF14431.6 KFM75067.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 YwqJ-like deaminase HTH_Tnp_Tc3_2 PF01498.18 KFM75068.1 - 7.6e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75068.1 - 1.8e-15 57.0 0.1 2.1e-14 53.5 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM75068.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM75068.1 - 0.0014 18.4 0.0 0.057 13.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75068.1 - 0.0029 17.7 0.2 0.012 15.8 0.2 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM75068.1 - 0.0084 15.9 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Tc3 transposase HTH_29 PF13551.6 KFM75068.1 - 0.034 14.2 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix zf-C4 PF00105.18 KFM75069.1 - 1.3e-22 80.1 14.8 2.8e-22 78.9 14.8 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFM75069.1 - 4.2e-09 36.3 0.4 4.2e-09 36.3 0.4 2.0 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 KFM75069.1 - 0.0025 17.9 9.1 0.0025 17.9 9.1 2.5 2 0 0 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type Kelch_1 PF01344.25 KFM75069.1 - 0.013 15.1 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Kelch motif HTH_Tnp_Tc3_2 PF01498.18 KFM75071.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75071.1 - 4.5e-14 52.4 0.0 7.3e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75072.1 - 2.2e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75072.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Aminopep PF10023.9 KFM75073.1 - 0.032 13.6 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative aminopeptidase Arc_C PF18162.1 KFM75074.1 - 1.7e-05 24.6 0.6 5.4e-05 23.0 0.6 1.8 1 0 0 1 1 1 1 Arc C-lobe RVT_1 PF00078.27 KFM75074.1 - 0.00017 21.2 0.0 0.00038 20.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 KFM75074.1 - 0.016 15.4 0.5 0.16 12.3 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein AcetylCoA_hydro PF02550.15 KFM75074.1 - 0.038 14.0 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain DDE_3 PF13358.6 KFM75075.1 - 2.1e-08 34.1 0.1 5.3e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Arc_C PF18162.1 KFM75075.1 - 0.00069 19.4 0.4 0.0017 18.2 0.4 1.6 1 0 0 1 1 1 1 Arc C-lobe Retrotrans_gag PF03732.17 KFM75075.1 - 0.0018 18.5 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Peptidase_A17 PF05380.13 KFM75076.1 - 1.8e-30 106.1 0.6 9.8e-30 103.7 0.0 2.1 2 0 0 2 2 2 1 Pao retrotransposon peptidase DUF5641 PF18701.1 KFM75076.1 - 4.1e-18 65.3 0.0 1.1e-17 64.0 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5641) K_channel_TID PF07941.11 KFM75079.1 - 0.31 11.5 15.1 0.77 10.3 3.5 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Clat_adaptor_s PF01217.20 KFM75080.1 - 1e-61 207.0 7.7 1.1e-61 206.9 7.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PNTB PF02233.16 KFM75081.1 - 4.3e-183 609.4 31.4 1.6e-182 607.5 22.4 2.1 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KFM75081.1 - 2.7e-77 258.9 0.1 6.9e-77 257.6 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KFM75081.1 - 6.7e-43 146.3 0.0 2e-42 144.7 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KFM75081.1 - 1.4e-32 112.0 4.7 1.4e-32 112.0 4.7 4.4 3 1 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TPP_enzyme_M PF00205.22 KFM75081.1 - 0.00056 19.7 0.4 0.96 9.2 0.0 3.3 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.19 KFM75081.1 - 0.0033 16.8 0.2 0.56 9.5 0.1 2.7 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KFM75081.1 - 0.017 14.4 0.3 0.031 13.5 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFM75081.1 - 0.079 13.4 0.1 5.1 7.6 0.1 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KFM75081.1 - 0.1 11.7 0.4 0.16 11.0 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Cytochrom_B561 PF03188.16 KFM75081.1 - 1.7 8.8 7.7 0.082 13.0 0.8 2.4 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 HTH_Tnp_Tc3_2 PF01498.18 KFM75082.1 - 2.7e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75082.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75082.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75082.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75082.1 - 1.8 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Homeodomain PF00046.29 KFM75085.1 - 2.5e-22 78.5 4.9 5e-22 77.5 4.9 1.5 1 0 0 1 1 1 1 Homeodomain zf-NF-X1 PF01422.17 KFM75086.1 - 8.8e-05 22.5 39.9 0.00021 21.2 9.8 7.6 7 3 0 7 7 7 4 NF-X1 type zinc finger Sushi PF00084.20 KFM75087.1 - 1.5e-08 35.1 0.0 2.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) F5_F8_type_C PF00754.25 KFM75087.1 - 2.3e-06 27.8 0.0 3.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Sushi PF00084.20 KFM75089.1 - 2.9e-09 37.4 0.6 7.2e-09 36.1 0.6 1.7 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) SH3_9 PF14604.6 KFM75091.1 - 2.2e-11 43.4 0.1 5e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFM75091.1 - 2.2e-07 30.4 0.0 4.6e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFM75091.1 - 5.6e-07 29.2 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RhoGAP PF00620.27 KFM75091.1 - 0.0025 17.7 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KFM75093.1 - 0.00031 21.2 0.0 0.00037 21.0 0.0 1.1 1 0 0 1 1 1 1 PH domain TTL PF03133.15 KFM75094.1 - 1.5e-30 106.4 0.0 1.6e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family TTL PF03133.15 KFM75095.1 - 9.3e-24 84.1 0.0 1.4e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFM75095.1 - 6.1e-06 25.7 0.0 9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFM75095.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 KFM75095.1 - 0.053 13.1 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Nop16 PF09420.10 KFM75096.1 - 1.4e-21 77.5 8.8 4.7e-17 62.7 0.2 2.1 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 RPW8 PF05659.11 KFM75096.1 - 0.026 14.2 0.4 0.026 14.2 0.4 1.8 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 zf-H2C2_2 PF13465.6 KFM75097.1 - 1.1e-26 92.0 24.7 8.7e-11 41.7 1.0 4.4 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75097.1 - 1.1e-17 63.4 21.9 5.4e-08 32.9 1.7 4.3 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75097.1 - 5.5e-10 39.2 19.8 7.9e-05 23.2 1.3 4.2 5 0 0 5 5 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM75097.1 - 1.1e-09 38.0 18.4 0.0021 18.0 0.4 3.9 3 1 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM75097.1 - 2.3e-09 37.4 25.3 0.00061 20.1 0.7 4.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM75097.1 - 1.1e-06 28.7 20.9 0.0003 21.0 0.2 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM75097.1 - 5.5e-05 22.8 3.0 0.0032 17.2 0.4 4.6 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 KFM75097.1 - 0.00079 19.2 8.9 0.79 9.6 0.1 3.1 1 1 2 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-CHCC PF10276.9 KFM75097.1 - 0.00085 19.3 0.2 6.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM75097.1 - 0.0014 18.7 5.3 1.2 9.2 0.0 3.4 2 1 1 3 3 3 1 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM75097.1 - 0.0015 18.3 1.6 1.6 8.6 0.0 3.0 1 1 2 3 3 3 1 GAGA factor zf-C2H2_2 PF12756.7 KFM75097.1 - 0.0016 18.7 18.3 0.44 10.9 3.2 3.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM75097.1 - 0.0016 18.2 8.5 0.53 10.2 0.3 3.5 3 1 0 3 3 3 1 zinc-finger of a C2HC-type C1_1 PF00130.22 KFM75097.1 - 0.0038 17.1 13.2 0.91 9.5 0.8 3.3 1 1 2 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) TRAF6_Z2 PF18048.1 KFM75097.1 - 0.0086 16.1 11.0 0.55 10.4 1.6 4.0 4 1 0 4 4 4 1 TNF receptor-associated factor 6 zinc finger 2 DUF2256 PF10013.9 KFM75097.1 - 0.0087 16.2 3.9 6.2 7.0 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM75097.1 - 0.012 15.5 2.1 0.66 10.0 2.1 2.4 1 1 2 3 3 3 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 KFM75097.1 - 0.012 15.5 6.8 4.6 7.2 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 KFM75097.1 - 0.021 14.9 8.4 7.4 6.8 0.1 3.0 1 1 0 2 2 2 0 KIAA1045 RING finger YyzF PF14116.6 KFM75097.1 - 0.028 14.4 3.7 12 6.1 0.1 3.1 3 0 0 3 3 3 0 YyzF-like protein Rpr2 PF04032.16 KFM75097.1 - 0.16 12.3 10.0 0.13 12.6 1.2 2.5 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HNH_5 PF14279.6 KFM75097.1 - 0.16 11.8 8.5 3.2 7.7 3.1 3.0 2 1 0 2 2 2 0 HNH endonuclease zf-Paramyx-P PF13008.7 KFM75097.1 - 0.16 11.4 4.6 20 4.7 0.2 3.1 3 0 0 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein zf-BED PF02892.15 KFM75097.1 - 0.18 11.8 15.5 0.46 10.6 3.0 3.2 1 1 2 3 3 3 0 BED zinc finger NADH-G_4Fe-4S_3 PF10588.9 KFM75097.1 - 0.22 11.1 8.0 7.4 6.2 0.2 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-RRPl_C4 PF17026.5 KFM75097.1 - 0.25 11.4 7.1 2.3 8.3 7.1 2.0 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type FYVE PF01363.21 KFM75097.1 - 0.28 11.3 13.1 3.6 7.8 13.1 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_8 PF15909.5 KFM75097.1 - 0.32 11.3 6.8 0.19 12.1 3.0 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KFM75097.1 - 0.45 10.3 9.9 1.8 8.4 0.5 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type DZR PF12773.7 KFM75097.1 - 0.75 9.9 6.3 5.1 7.2 6.3 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF2072 PF09845.9 KFM75097.1 - 0.84 9.9 8.3 24 5.2 0.2 3.1 3 0 0 3 3 3 0 Zn-ribbon containing protein zf-HIT PF04438.16 KFM75097.1 - 0.9 9.5 9.6 12 5.9 0.4 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-MYST PF17772.1 KFM75097.1 - 0.97 9.1 6.0 3.9 7.1 0.5 2.9 1 1 2 3 3 3 0 MYST family zinc finger domain zf_ZIC PF18366.1 KFM75097.1 - 4.8 7.4 13.8 5.5 7.2 0.6 3.2 1 1 2 3 3 3 0 Zic proteins zinc finger domain Zn-C2H2_12 PF18112.1 KFM75097.1 - 8.4 7.0 17.9 7.6 7.1 0.1 4.3 4 1 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain LRR_8 PF13855.6 KFM75099.1 - 4.1e-43 145.0 62.5 4.3e-14 52.0 10.0 7.0 4 3 4 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 KFM75099.1 - 5.3e-22 77.5 48.7 2.3e-05 24.7 7.5 9.2 7 3 3 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM75099.1 - 8.6e-15 54.8 4.1 0.0012 18.8 0.1 4.2 4 0 0 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM75099.1 - 1.6e-13 49.1 42.1 0.07 13.7 0.1 11.5 13 0 0 13 13 13 7 Leucine Rich Repeat LRR_6 PF13516.6 KFM75099.1 - 1.8e-10 40.0 34.3 0.3 11.2 0.1 10.2 12 0 0 12 12 12 6 Leucine Rich repeat LRR_9 PF14580.6 KFM75099.1 - 2.4e-08 33.7 13.7 1.1e-05 25.1 0.9 4.9 1 1 4 5 5 5 3 Leucine-rich repeat LRR_8 PF13855.6 KFM75100.1 - 1.2e-21 76.2 17.7 5.2e-11 42.1 0.8 3.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_5 PF13306.6 KFM75100.1 - 2e-11 44.0 4.2 2.2e-11 43.8 4.2 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM75100.1 - 0.00037 20.8 13.2 0.01 16.3 2.8 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM75100.1 - 0.0023 17.5 0.5 0.0038 16.7 0.2 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KFM75101.1 - 9.8e-13 47.7 4.7 1.6e-09 37.4 0.4 1.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KFM75101.1 - 4.6e-05 23.4 0.3 0.41 11.4 0.1 2.9 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_5 PF13306.6 KFM75101.1 - 0.00019 21.4 0.1 0.0002 21.3 0.1 1.0 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM75101.1 - 0.00048 20.5 1.4 0.0015 18.9 0.4 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM75101.1 - 0.037 14.1 0.3 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeat GM_CSF PF01109.17 KFM75103.1 - 0.012 15.8 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Phage_gp49_66 PF13876.6 KFM75104.1 - 0.03 14.6 0.0 0.034 14.5 0.0 1.1 1 0 0 1 1 1 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family HTH_Tnp_Tc3_2 PF01498.18 KFM75105.1 - 1.9e-16 60.1 2.2 4.2e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75105.1 - 8.7e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_2 PF07727.14 KFM75106.1 - 9.9e-73 244.7 0.1 1.2e-72 244.5 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFM75106.1 - 0.0003 20.4 0.0 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3242 PF11586.8 KFM75106.1 - 0.091 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) DUF2536 PF10750.9 KFM75106.1 - 0.13 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) Arg_repressor_C PF02863.18 KFM75106.1 - 0.5 10.3 1.4 5.4 6.9 0.1 2.4 1 1 1 2 2 2 0 Arginine repressor, C-terminal domain RNB PF00773.19 KFM75107.1 - 2.5e-94 316.3 0.6 5.1e-94 315.2 0.1 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 KFM75107.1 - 5.1e-21 74.5 0.0 1.2e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 KFM75107.1 - 7.6e-10 38.7 0.0 1.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 KFM75107.1 - 2.8e-08 33.8 2.1 1.1e-06 28.6 0.1 3.5 3 1 1 4 4 4 1 Cold shock domain Rrp44_S1 PF17215.3 KFM75107.1 - 3.3e-07 30.2 0.1 8.5e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 S1 domain OB_RNB PF08206.11 KFM75107.1 - 0.078 12.7 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain CSRNP_N PF16019.5 KFM75108.1 - 5.9e-92 307.5 13.4 5.9e-92 307.5 13.4 2.8 3 0 0 3 3 3 1 Cysteine/serine-rich nuclear protein N-terminus SUI1 PF01253.22 KFM75109.1 - 3.4e-28 98.0 2.2 5.2e-28 97.4 2.2 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 DuoxA PF10204.9 KFM75113.1 - 1.1e-27 96.8 8.1 1.4e-27 96.4 8.1 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor DUF2105 PF09878.9 KFM75113.1 - 0.024 14.4 5.0 0.035 13.8 5.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) Guanylate_cyc PF00211.20 KFM75114.1 - 3.9e-53 179.8 0.5 2.1e-46 157.8 0.0 2.2 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1858 PF08984.11 KFM75114.1 - 0.057 13.6 0.2 3.8 7.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1858) AMP-binding PF00501.28 KFM75114.1 - 0.089 11.4 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme Spore_YhcN_YlaJ PF09580.10 KFM75114.1 - 0.1 12.6 0.0 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) RL PF17797.1 KFM75115.1 - 8.6e-08 32.0 0.0 1.8e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 RL domain NTP_transf_2 PF01909.23 KFM75115.1 - 6.2e-06 26.4 0.0 2.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KFM75115.1 - 0.0073 16.5 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Nrap_D2 PF17403.2 KFM75115.1 - 0.04 13.7 0.3 0.091 12.5 0.0 1.7 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain Peptidase_M2 PF01401.18 KFM75116.1 - 1.6e-246 819.4 15.9 1.9e-246 819.2 15.9 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme HrpB_C PF08482.10 KFM75116.1 - 0.044 14.2 0.8 0.32 11.4 0.1 2.6 3 0 0 3 3 3 0 ATP-dependent helicase C-terminal Peptidase_M2 PF01401.18 KFM75117.1 - 1.2e-38 133.2 0.1 1.3e-38 133.0 0.1 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme CoaE PF01121.20 KFM75118.1 - 0.082 12.6 0.4 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase Peptidase_M2 PF01401.18 KFM75119.1 - 4.8e-64 217.0 0.4 5.4e-64 216.8 0.4 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme MULE PF10551.9 KFM75120.1 - 1.3e-07 31.9 0.1 2.6e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 MULE transposase domain DUF5575 PF17738.1 KFM75120.1 - 0.15 11.1 1.7 1 8.3 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5575) Utp11 PF03998.13 KFM75121.1 - 0.0087 16.0 5.0 0.0096 15.9 5.0 1.1 1 0 0 1 1 1 1 Utp11 protein NFACT-R_2 PF18297.1 KFM75121.1 - 0.081 13.1 0.8 0.74 10.0 0.1 2.1 1 1 1 2 2 2 0 NFACT protein RNA binding domain TFCD_C PF12612.8 KFM75122.1 - 3e-55 187.0 1.8 3.4e-53 180.3 0.0 4.1 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KFM75122.1 - 2.1e-08 33.7 10.3 0.14 12.5 0.1 9.0 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 KFM75122.1 - 8.8e-07 29.2 0.1 2.9 8.4 0.0 5.6 5 1 0 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 KFM75122.1 - 0.00023 21.6 6.3 1.1 9.8 0.0 7.2 9 1 1 10 10 10 1 HEAT-like repeat Cnd1 PF12717.7 KFM75122.1 - 0.011 15.8 1.0 16 5.5 0.0 4.6 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 AAA_lid_3 PF17862.1 KFM75122.1 - 0.031 14.1 0.3 0.41 10.5 0.1 2.4 2 0 0 2 2 2 0 AAA+ lid domain PUL PF08324.11 KFM75122.1 - 0.082 12.1 0.1 0.69 9.1 0.0 2.4 2 1 1 3 3 3 0 PUL domain Poxvirus PF06227.12 KFM75122.1 - 0.094 12.5 0.0 0.36 10.6 0.0 2.0 1 0 0 1 1 1 0 dsDNA Poxvirus Arm PF00514.23 KFM75122.1 - 0.12 12.5 2.5 33 4.7 0.1 4.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 KFM75122.1 - 0.8 8.4 3.3 20 3.8 0.0 3.8 5 0 0 5 5 5 0 Apoptosis inhibitory protein 5 (API5) RRM_1 PF00076.22 KFM75123.1 - 5.1e-13 48.6 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM75123.1 - 0.036 14.2 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Macoilin PF09726.9 KFM75123.1 - 8.1 4.9 12.2 11 4.4 12.2 1.1 1 0 0 1 1 1 0 Macoilin family zf-H2C2_2 PF13465.6 KFM75125.1 - 3.3e-69 226.4 71.1 4.5e-08 33.2 0.7 11.3 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75125.1 - 3.5e-55 181.5 93.5 4.1e-06 26.9 0.7 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75125.1 - 1.7e-40 134.2 86.9 0.00033 21.3 1.8 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM75125.1 - 2.3e-24 84.9 69.1 0.00033 20.6 1.3 11.5 11 0 0 11 11 11 10 C2H2-type zinc finger zf-met PF12874.7 KFM75125.1 - 1.4e-15 57.1 81.2 0.01 16.2 0.9 11.2 11 0 0 11 11 11 9 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM75125.1 - 6e-14 51.5 53.9 0.1 12.4 0.3 12.0 11 1 0 11 11 11 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM75125.1 - 5.8e-10 39.2 70.3 0.073 13.4 1.8 11.4 10 1 1 11 11 11 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM75125.1 - 2e-07 31.2 5.7 0.22 11.8 0.4 6.6 4 2 2 6 6 6 2 BolA-like protein Baculo_IE-1 PF05290.11 KFM75125.1 - 0.00011 22.2 36.3 8.5 6.3 7.8 8.3 1 1 4 6 6 6 1 Baculovirus immediate-early protein (IE-0) zf-C2HC_2 PF13913.6 KFM75125.1 - 0.041 13.8 0.3 0.041 13.8 0.3 9.8 11 0 0 11 11 11 0 zinc-finger of a C2HC-type zf-RING_11 PF17123.5 KFM75125.1 - 0.07 12.9 29.4 0.19 11.5 1.1 8.2 8 0 0 8 8 8 0 RING-like zinc finger zf-C2H2_2 PF12756.7 KFM75125.1 - 0.16 12.4 67.5 2.7 8.4 1.3 9.9 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM75125.1 - 0.26 12.1 44.6 3.6 8.4 3.6 5.6 1 1 2 5 5 5 0 zinc-ribbon family FYVE PF01363.21 KFM75125.1 - 0.4 10.9 64.6 2.4 8.4 5.3 7.6 1 1 3 5 5 5 0 FYVE zinc finger DUF3280 PF11684.8 KFM75125.1 - 0.49 10.8 14.2 40 4.6 0.1 6.3 2 2 5 7 7 7 0 Protein of unknown function (DUF2380) YceD PF02620.17 KFM75125.1 - 3.5 7.8 0.0 3.5 7.8 0.0 6.5 3 1 4 7 7 7 0 Large ribosomal RNA subunit accumulation protein YceD Spore_III_AB PF09548.10 KFM75126.1 - 0.00036 20.7 5.3 0.00041 20.5 5.3 1.1 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) WXG100 PF06013.12 KFM75126.1 - 0.0092 16.2 2.3 0.029 14.6 2.3 1.7 1 1 0 1 1 1 1 Proteins of 100 residues with WXG DUF842 PF05811.13 KFM75126.1 - 0.0094 15.6 4.8 0.014 15.1 4.8 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF148 PF02520.17 KFM75126.1 - 0.011 15.8 8.3 0.29 11.3 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF1451 PF07295.11 KFM75126.1 - 0.014 15.5 4.4 0.017 15.1 4.4 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain Spectrin PF00435.21 KFM75126.1 - 0.022 15.2 6.6 0.044 14.3 6.5 1.6 1 1 1 2 2 2 0 Spectrin repeat RRF PF01765.19 KFM75126.1 - 0.028 14.4 8.3 0.033 14.2 8.3 1.2 1 0 0 1 1 1 0 Ribosome recycling factor TetR_C_24 PF17932.1 KFM75126.1 - 0.034 14.4 2.7 0.044 14.1 2.5 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ApoLp-III PF07464.11 KFM75126.1 - 0.037 14.1 8.2 0.05 13.7 8.2 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF5054 PF16477.5 KFM75126.1 - 0.09 12.5 2.8 0.098 12.4 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5054) tRNA_bind_2 PF13725.6 KFM75126.1 - 0.12 12.0 8.4 0.15 11.8 8.4 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain Mitofilin PF09731.9 KFM75126.1 - 0.13 11.0 12.3 0.16 10.8 12.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Prominin PF05478.11 KFM75126.1 - 0.14 10.1 4.6 0.15 10.0 4.6 1.0 1 0 0 1 1 1 0 Prominin DUF737 PF05300.11 KFM75126.1 - 0.15 12.4 10.8 0.17 12.2 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF1640 PF07798.11 KFM75126.1 - 0.18 11.9 9.3 0.29 11.2 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1664 PF07889.12 KFM75126.1 - 0.19 11.7 8.3 0.42 10.7 8.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KFM75126.1 - 0.24 11.5 10.4 3.2 7.8 10.4 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3511 PF12023.8 KFM75126.1 - 0.3 11.0 2.6 4.8 7.1 0.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3511) DUF883 PF05957.13 KFM75126.1 - 0.33 11.6 5.1 0.53 10.9 4.8 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HSP9_HSP12 PF04119.12 KFM75126.1 - 0.42 11.0 7.6 3.1 8.3 6.6 2.4 1 1 2 3 3 3 0 Heat shock protein 9/12 TMPIT PF07851.13 KFM75126.1 - 0.43 9.8 8.2 0.48 9.6 8.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein AvrM-A PF18241.1 KFM75126.1 - 0.47 10.8 9.9 0.51 10.7 9.9 1.1 1 0 0 1 1 1 0 Flax-rust effector AvrM-A Atg14 PF10186.9 KFM75126.1 - 0.54 9.3 4.3 0.64 9.0 4.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HCO3_cotransp PF00955.21 KFM75126.1 - 0.77 8.5 2.5 0.81 8.4 2.5 1.0 1 0 0 1 1 1 0 HCO3- transporter family Z1 PF10593.9 KFM75126.1 - 0.92 9.0 5.7 1.6 8.2 5.7 1.5 1 1 0 1 1 1 0 Z1 domain TipAS PF07739.13 KFM75126.1 - 1 9.9 9.2 0.99 10.0 8.1 1.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain UVR PF02151.19 KFM75126.1 - 1.6 8.5 12.9 3.1 7.7 1.3 3.6 2 1 1 3 3 3 0 UvrB/uvrC motif YtxH PF12732.7 KFM75126.1 - 3.6 8.2 13.6 1.2e+02 3.4 13.6 2.1 1 1 0 1 1 1 0 YtxH-like protein Lectin_C PF00059.21 KFM75127.1 - 3.1e-24 85.8 4.0 7.6e-15 55.6 0.2 2.4 2 0 0 2 2 2 2 Lectin C-type domain DUF4505 PF14956.6 KFM75127.1 - 0.093 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) TORC_N PF12884.7 KFM75128.1 - 3.1e-21 75.9 1.5 3.2e-21 75.9 1.5 1.0 1 0 0 1 1 1 1 Transducer of regulated CREB activity, N terminus TORC_M PF12885.7 KFM75129.1 - 1.7e-29 102.8 5.8 1e-28 100.3 5.8 1.9 1 1 0 1 1 1 1 Transducer of regulated CREB activity middle domain TORC_C PF12886.7 KFM75131.1 - 1.7e-13 50.9 1.1 2.5e-11 44.0 0.2 3.0 2 1 0 2 2 2 1 Transducer of regulated CREB activity, C terminus HTH_Tnp_Tc3_2 PF01498.18 KFM75133.1 - 2.1e-16 59.9 2.2 4.4e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75133.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MMR_HSR1_Xtn PF16897.5 KFM75134.1 - 9e-42 141.4 0.2 1.8e-41 140.4 0.2 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KFM75134.1 - 4.8e-24 84.2 0.1 8e-24 83.5 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KFM75134.1 - 5.2e-21 74.9 0.0 1.1e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM75134.1 - 7.8e-11 41.7 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFM75134.1 - 0.0012 19.0 0.3 1.9 8.5 0.0 2.6 3 0 0 3 3 3 2 Dynamin family AAA_28 PF13521.6 KFM75134.1 - 0.057 13.7 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM75134.1 - 0.073 13.0 0.1 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KFM75134.1 - 0.11 13.0 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 KFM75134.1 - 0.14 11.6 1.4 0.79 9.1 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFM75134.1 - 0.14 11.6 1.0 5.5 6.5 0.2 3.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain G10 PF01125.17 KFM75135.1 - 8.4e-66 220.2 6.1 9.3e-66 220.1 6.1 1.0 1 0 0 1 1 1 1 G10 protein Hairy_orange PF07527.13 KFM75136.1 - 8e-11 42.0 0.3 1.3e-10 41.3 0.3 1.4 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 KFM75137.1 - 1.1e-07 31.7 6.8 1.2e-07 31.6 6.1 1.4 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain THAP PF05485.12 KFM75138.1 - 5.3e-17 62.5 1.8 9.7e-17 61.7 1.8 1.4 1 0 0 1 1 1 1 THAP domain PfkB PF00294.24 KFM75139.1 - 5.6e-09 35.7 0.0 6.2e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Aminotran_5 PF00266.19 KFM75140.1 - 3.3e-12 46.1 0.0 4.3e-12 45.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFM75140.1 - 0.027 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFM75140.1 - 0.056 12.0 0.0 0.12 10.9 0.0 1.4 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme HTH_Tnp_Tc3_2 PF01498.18 KFM75141.1 - 3e-16 59.4 3.0 6.3e-16 58.4 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75141.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75141.1 - 3.1e-07 30.0 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75141.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75141.1 - 0.029 14.5 0.4 0.098 12.8 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM75141.1 - 2.6 8.7 15.6 0.13 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DUF4371 PF14291.6 KFM75142.1 - 1.6e-08 34.5 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) PepX_C PF08530.10 KFM75142.1 - 0.031 14.2 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain P34-Arc PF04045.14 KFM75143.1 - 2.1e-104 348.5 0.5 2.6e-104 348.2 0.5 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 KFM75143.1 - 0.0025 17.5 0.2 0.027 14.1 0.3 2.3 2 1 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) Microcin PF03526.13 KFM75145.1 - 0.72 9.7 4.0 1.3 8.9 4.0 1.6 1 1 0 1 1 1 0 Colicin E1 (microcin) immunity protein LRR_4 PF12799.7 KFM75146.1 - 2.6e-07 30.8 2.8 0.00059 20.2 0.1 5.9 1 1 4 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM75146.1 - 8.1e-05 22.7 16.6 3.8 8.4 0.2 7.5 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.6 KFM75146.1 - 0.23 11.6 15.7 75 3.8 0.0 7.5 8 0 0 8 8 8 0 Leucine Rich repeat LRR_8 PF13855.6 KFM75146.1 - 1 9.2 11.2 6.8 6.5 1.4 4.8 5 1 2 7 7 7 0 Leucine rich repeat RRM_1 PF00076.22 KFM75147.1 - 9.8e-17 60.5 0.2 1.8e-16 59.7 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM75147.1 - 0.002 18.2 0.1 0.0058 16.7 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 KFM75147.1 - 0.0024 18.1 1.6 0.0048 17.1 1.6 1.6 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KFM75147.1 - 0.027 14.5 0.1 0.051 13.6 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 KFM75147.1 - 0.056 13.4 0.3 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 RL domain ApoL PF05461.11 KFM75148.1 - 4.8e-14 52.4 3.7 6.7e-14 51.9 2.6 1.8 1 1 1 2 2 2 1 Apolipoprotein L Tubulin PF00091.25 KFM75149.1 - 2.8e-68 230.0 0.0 3.8e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM75149.1 - 1.1e-51 174.3 0.0 1.7e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFM75149.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DDE_3 PF13358.6 KFM75150.1 - 1e-12 48.1 0.0 1.4e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease BACK PF07707.15 KFM75151.1 - 2.2e-05 24.5 1.5 0.00026 21.0 0.4 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFM75151.1 - 0.00066 19.9 0.6 0.00066 19.9 0.6 1.8 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KFM75152.1 - 6.3e-18 65.0 0.0 1.6e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 KFM75153.1 - 1.4e-34 118.6 0.1 3.3e-22 78.8 0.2 2.4 2 0 0 2 2 2 2 BTB/POZ domain fn3 PF00041.21 KFM75154.1 - 3.5e-90 296.5 0.0 5e-11 42.8 0.0 10.0 9 1 0 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM75154.1 - 2e-28 98.8 1.3 0.0003 21.3 0.0 10.2 9 1 0 9 9 9 6 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM75154.1 - 2.2e-10 40.8 4.6 0.19 12.0 0.2 8.0 9 0 0 9 9 9 2 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 KFM75154.1 - 2.7e-07 30.6 0.1 1.6 8.9 0.0 4.7 4 0 0 4 4 4 3 Fibronectin type III domain DUF2369 PF10179.9 KFM75154.1 - 6.4e-07 29.7 0.0 24 5.4 0.0 7.6 8 1 1 9 9 9 2 Uncharacterised conserved protein (DUF2369) GPI-anchored PF10342.9 KFM75154.1 - 0.19 12.5 2.4 78 4.1 0.0 5.4 7 0 0 7 7 7 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HTH_Tnp_Tc3_2 PF01498.18 KFM75155.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75155.1 - 2.3e-13 50.1 0.0 3.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75156.1 - 2.2e-12 47.0 0.2 4.7e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75156.1 - 3.3e-12 46.4 0.0 5.1e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75157.1 - 4.9e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75157.1 - 1.3e-13 50.9 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75157.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75157.1 - 0.0027 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75157.1 - 2.4 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM75158.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75158.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75158.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75158.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75158.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Paf1 PF03985.13 KFM75159.1 - 9.1e-83 278.6 30.4 9.1e-83 278.6 30.4 2.0 1 1 1 2 2 2 1 Paf1 LRR_9 PF14580.6 KFM75160.1 - 1.1e-09 38.1 12.8 6.3e-06 25.8 0.2 3.7 1 1 3 4 4 4 4 Leucine-rich repeat LRR_4 PF12799.7 KFM75160.1 - 1e-08 35.3 29.0 0.0037 17.6 2.8 5.5 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.6 KFM75160.1 - 3.3e-06 27.4 0.1 7e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_8 PF13855.6 KFM75160.1 - 0.047 13.5 18.0 0.12 12.2 1.8 4.4 3 2 1 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 KFM75160.1 - 1.8 9.4 9.8 63 4.7 0.2 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat CAP_GLY PF01302.25 KFM75161.1 - 2.5e-15 56.3 0.8 2.8e-15 56.1 0.8 1.0 1 0 0 1 1 1 1 CAP-Gly domain GAT PF03127.14 KFM75164.1 - 5e-08 33.1 0.1 8.1e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 GAT domain APOBEC1 PF18769.1 KFM75165.1 - 0.038 14.2 0.2 0.042 14.1 0.2 1.1 1 0 0 1 1 1 0 APOBEC1 Pkinase PF00069.25 KFM75166.1 - 1.8e-08 34.1 0.0 2e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain FliG_N PF14842.6 KFM75166.1 - 0.0041 17.6 0.0 0.0054 17.2 0.0 1.2 1 0 0 1 1 1 1 FliG N-terminal domain Pkinase PF00069.25 KFM75167.1 - 2.2e-48 164.9 0.0 2.7e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM75167.1 - 3.2e-17 62.7 0.0 4.2e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM75167.1 - 5.4e-06 25.9 0.0 6.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM75167.1 - 0.008 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFM75167.1 - 0.023 13.7 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFM75167.1 - 0.03 14.2 0.3 0.066 13.1 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family HTH_10 PF04967.12 KFM75168.1 - 1.5e-14 53.5 13.8 0.85 9.5 0.1 7.9 7 0 0 7 7 7 6 HTH DNA binding domain HTH_Tnp_4 PF13613.6 KFM75168.1 - 2.5e-12 46.3 19.9 0.69 9.7 0.1 6.9 7 0 0 7 7 7 6 Helix-turn-helix of DDE superfamily endonuclease HHH_5 PF14520.6 KFM75168.1 - 5.7e-12 46.1 18.2 1.4 9.6 0.1 7.6 7 0 0 7 7 7 6 Helix-hairpin-helix domain Spidroin_N PF16763.5 KFM75168.1 - 3.1e-10 40.2 0.7 3.1e-10 40.2 0.7 16.0 8 7 3 15 15 9 1 Major ampullate spidroin 1, spider silk protein 1, N-term RP1-2 PF12042.8 KFM75168.1 - 2.2e-07 30.9 491.7 0.00035 20.5 48.0 12.8 2 1 6 8 8 7 1 Tubuliform egg casing silk strands structural domain Sigma70_r4 PF04545.16 KFM75168.1 - 7.1e-07 28.6 4.4 45 3.7 0.0 7.3 7 0 0 7 7 7 0 Sigma-70, region 4 TonB_N PF16031.5 KFM75168.1 - 0.0011 19.5 82.0 1.5 9.3 5.8 7.7 7 0 0 7 7 7 6 TonB polyproline region IL11 PF07400.11 KFM75168.1 - 0.0029 17.3 22.9 24 4.5 0.1 7.4 7 0 0 7 7 7 0 Interleukin 11 SGTA_dimer PF16546.5 KFM75168.1 - 0.0088 15.8 38.2 6.4 6.6 1.0 7.3 6 0 0 6 6 6 6 Homodimerisation domain of SGTA Integrase_Zn PF02022.19 KFM75168.1 - 0.019 14.9 18.1 55 3.8 0.1 6.8 6 0 0 6 6 6 0 Integrase Zinc binding domain RNA_pol_L PF01193.24 KFM75168.1 - 0.23 10.9 6.7 2.9e+02 1.0 0.0 6.7 7 0 0 7 7 7 0 RNA polymerase Rpb3/Rpb11 dimerisation domain HTH_psq PF05225.16 KFM75168.1 - 5.1 6.9 26.2 80 3.1 0.2 9.1 7 5 0 7 7 7 0 helix-turn-helix, Psq domain COS PF18568.1 KFM75168.1 - 9.9 6.2 40.9 31 4.6 0.6 8.8 7 0 0 7 7 7 0 TRIM C-terminal subgroup One Signature domain C2-set_2 PF08205.12 KFM75169.1 - 2.3e-05 24.4 0.0 2.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFM75169.1 - 4.8e-05 23.6 0.0 5.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM75169.1 - 0.00051 20.6 0.0 0.00056 20.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Sushi PF00084.20 KFM75169.1 - 0.1 13.2 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Sushi repeat (SCR repeat) PEP-utilizers PF00391.23 KFM75170.1 - 3.4e-20 71.5 0.0 5.3e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PPDK_N PF01326.19 KFM75171.1 - 5.3e-66 223.1 0.0 9.9e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain LRR_4 PF12799.7 KFM75172.1 - 1.1e-22 79.8 34.2 1.8e-07 31.4 4.1 6.3 3 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM75172.1 - 1.5e-20 72.7 34.4 1.2e-06 28.1 3.1 5.5 4 1 2 6 6 6 6 Leucine rich repeat LRR_6 PF13516.6 KFM75172.1 - 3.3e-09 36.1 25.1 0.069 13.2 0.2 8.6 7 1 2 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.33 KFM75172.1 - 1.9e-08 33.7 31.8 0.32 11.7 0.1 9.1 7 2 1 8 8 8 5 Leucine Rich Repeat LRR_9 PF14580.6 KFM75172.1 - 2e-05 24.1 7.9 0.0014 18.2 2.3 2.9 1 1 0 2 2 2 2 Leucine-rich repeat Tho2 PF11262.8 KFM75173.1 - 1.1e-99 333.5 2.7 1.1e-99 333.5 2.7 2.7 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KFM75173.1 - 7.3e-34 115.7 1.6 1.5e-33 114.7 0.1 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit THOC2_N PF16134.5 KFM75173.1 - 5.5e-23 81.5 0.1 5.5e-23 81.5 0.1 2.6 3 0 0 3 3 3 1 THO complex subunit 2 N-terminus THOC2_N PF16134.5 KFM75174.1 - 1.4e-44 152.8 1.6 1.5e-43 149.4 1.6 1.9 1 1 0 1 1 1 1 THO complex subunit 2 N-terminus Crisp PF08562.10 KFM75176.1 - 9.1e-14 51.8 17.4 1.7e-13 50.9 17.4 1.5 1 0 0 1 1 1 1 Crisp CAP PF00188.26 KFM75176.1 - 1.8e-09 38.5 3.8 2.8e-09 37.9 3.8 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Adeno_E3_CR1 PF02440.15 KFM75176.1 - 0.014 15.2 0.4 0.014 15.2 0.4 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 KH_1 PF00013.29 KFM75180.1 - 1.9e-08 34.0 0.4 2.8e-08 33.5 0.4 1.3 1 0 0 1 1 1 1 KH domain AKAP7_NLS PF10469.9 KFM75180.1 - 0.0059 16.5 0.2 0.0091 15.9 0.2 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_2 PF07650.17 KFM75180.1 - 0.055 13.3 0.4 0.11 12.3 0.3 1.5 1 1 0 1 1 1 0 KH domain 40S_S4_C PF16121.5 KFM75180.1 - 0.081 12.6 0.0 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 40S ribosomal protein S4 C-terminus AKAP7_NLS PF10469.9 KFM75181.1 - 1.1e-23 84.2 0.1 1.2e-23 84.1 0.1 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DUF4796 PF16044.5 KFM75181.1 - 0.07 12.7 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) DEAD PF00270.29 KFM75183.1 - 1.3e-46 158.5 0.4 2.2e-46 157.8 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM75183.1 - 8.2e-33 113.1 1.0 7.2e-32 110.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM75183.1 - 2.2e-07 31.0 0.0 4.8e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFM75183.1 - 0.00092 19.6 0.2 0.0076 16.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFM75183.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KFM75183.1 - 0.0041 17.0 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA PF00004.29 KFM75183.1 - 0.018 15.5 0.1 0.068 13.6 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM75183.1 - 0.041 14.2 1.7 0.1 12.8 0.4 2.3 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.6 KFM75183.1 - 0.048 13.0 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KFM75183.1 - 0.05 13.6 0.1 0.35 10.8 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain SMC_N PF02463.19 KFM75183.1 - 0.085 12.3 0.4 9.8 5.5 0.2 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ADK PF00406.22 KFM75184.1 - 1.1e-42 145.7 0.0 1.3e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFM75184.1 - 1.1e-37 129.5 0.0 1.4e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM75184.1 - 1.4e-08 35.0 0.0 2.4e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM75184.1 - 1.5e-07 32.0 0.0 2.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM75184.1 - 2.9e-05 23.5 0.0 5.3e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 KFM75184.1 - 0.0011 18.7 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.19 KFM75184.1 - 0.0066 16.3 0.0 0.036 13.9 0.0 1.9 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_19 PF13245.6 KFM75184.1 - 0.029 14.7 0.1 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KFM75184.1 - 0.078 12.7 0.1 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_22 PF13401.6 KFM75184.1 - 0.11 12.8 0.1 0.58 10.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain Arm PF00514.23 KFM75185.1 - 0.00025 21.0 0.1 1.3 9.2 0.0 4.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat LRR_4 PF12799.7 KFM75185.1 - 0.2 12.1 16.1 12 6.5 0.3 5.6 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM75185.1 - 3 8.8 10.5 88 4.3 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat HTH_Tnp_Tc3_2 PF01498.18 KFM75186.1 - 2.3e-16 59.8 2.2 4.3e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75186.1 - 6.4e-13 48.7 0.0 1.1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2_4 PF13894.6 KFM75187.1 - 9.5e-07 29.2 42.8 0.03 15.2 0.5 6.9 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM75187.1 - 1.6e-05 25.1 40.6 0.00071 19.9 1.0 6.7 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM75187.1 - 7.8e-05 22.9 26.5 0.0038 17.6 0.2 6.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_9 PF16293.5 KFM75187.1 - 0.0033 17.2 2.6 7 6.6 0.0 4.0 3 0 0 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KFM75187.1 - 0.46 10.8 23.0 0.025 14.8 2.9 4.0 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFM75187.1 - 0.5 10.2 12.0 3.5 7.4 0.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM75187.1 - 7.9 6.6 39.5 0.57 10.3 4.6 6.2 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM75187.1 - 8.9 6.7 36.4 1.2 9.5 3.0 6.7 4 2 2 6 6 6 0 C2H2 type zinc-finger (2 copies) Serinc PF03348.15 KFM75188.1 - 5.9e-164 546.1 28.5 6.6e-164 545.9 28.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Asp_protease PF09668.10 KFM75189.1 - 2.7e-59 198.4 0.8 4.7e-59 197.6 0.8 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM75189.1 - 2.4e-24 85.7 0.0 5.4e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 KFM75189.1 - 2.3e-10 40.0 0.1 6.6e-10 38.6 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Asp_protease_2 PF13650.6 KFM75189.1 - 3.4e-08 34.0 0.0 7.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KFM75189.1 - 0.00047 19.9 0.5 0.0026 17.5 0.5 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KFM75189.1 - 0.0039 17.5 0.1 0.013 15.8 0.1 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 KFM75189.1 - 0.027 14.3 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFM75189.1 - 0.071 13.6 0.0 0.22 12.0 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain YukD PF08817.10 KFM75189.1 - 0.097 13.4 0.0 0.48 11.2 0.0 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD DUF642 PF04862.12 KFM75191.1 - 0.096 12.5 0.0 0.096 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF642) PH_14 PF17787.1 KFM75192.1 - 2.5e-13 50.0 0.1 3.2e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 PH domain CRAL_TRIO PF00650.20 KFM75193.1 - 8e-31 106.9 0.5 8.6e-31 106.8 0.5 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM75193.1 - 6.2e-07 29.6 0.1 7.2e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Flavodoxin_2 PF02525.17 KFM75193.1 - 0.17 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold DDE_3 PF13358.6 KFM75196.1 - 2.7e-16 59.6 0.1 3e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75196.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase AROS PF15684.5 KFM75198.1 - 2.9e-08 34.3 19.3 4.4e-08 33.8 19.3 1.3 1 1 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 ZYG-11_interact PF05884.12 KFM75198.1 - 0.94 8.8 2.5 1.2 8.5 2.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 HTH_Tnp_Tc3_2 PF01498.18 KFM75199.1 - 1.7e-15 57.0 3.7 4.3e-15 55.7 3.7 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75199.1 - 1.1e-10 41.4 0.0 3.7e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_IclR PF09339.10 KFM75199.1 - 0.00027 20.7 0.0 0.00073 19.3 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_29 PF13551.6 KFM75199.1 - 0.0067 16.4 0.7 0.021 14.8 0.7 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 KFM75199.1 - 0.027 15.1 4.5 0.027 15.1 4.5 2.5 2 0 0 2 2 2 0 Homeodomain-like domain MarR_2 PF12802.7 KFM75199.1 - 0.033 14.1 0.8 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 MarR family HTH_23 PF13384.6 KFM75199.1 - 0.05 13.4 2.2 0.2 11.5 0.2 2.6 2 0 0 2 2 2 0 Homeodomain-like domain Avidin PF01382.17 KFM75201.1 - 0.091 13.2 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 Avidin family RVT_1 PF00078.27 KFM75202.1 - 2.3e-47 161.4 0.0 6.6e-47 159.9 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 KFM75202.1 - 7.4e-23 81.4 0.1 1.5e-22 80.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM75202.1 - 5.3e-19 68.2 0.1 5.3e-19 68.2 0.1 2.6 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase PRE_C2HC PF07530.11 KFM75202.1 - 1.6e-05 24.9 0.0 4.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Associated with zinc fingers Exo_endo_phos PF03372.23 KFM75202.1 - 8.7e-05 22.1 0.0 0.00036 20.1 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FMN_red PF03358.15 KFM75203.1 - 9.7e-11 41.6 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Tnp_P_element PF12017.8 KFM75205.1 - 2.5e-66 223.3 4.3 4.2e-66 222.5 4.3 1.4 1 0 0 1 1 1 1 Transposase protein THAP PF05485.12 KFM75205.1 - 9.9e-16 58.5 0.1 9.9e-16 58.5 0.1 2.8 3 0 0 3 3 3 1 THAP domain LAP2alpha PF11560.8 KFM75205.1 - 0.019 14.4 0.2 0.034 13.6 0.2 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha Wtap PF17098.5 KFM75205.1 - 0.025 14.5 4.1 0.058 13.3 4.1 1.6 1 0 0 1 1 1 0 WTAP/Mum2p family Med22 PF06179.12 KFM75208.1 - 2.1e-26 92.1 0.3 2.6e-26 91.8 0.3 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex tRNA_bind_4 PF18490.1 KFM75208.1 - 0.0051 16.6 0.1 0.0064 16.3 0.1 1.1 1 0 0 1 1 1 1 tRNA-binding domain Talin_middle PF09141.10 KFM75208.1 - 0.062 13.3 0.1 0.27 11.2 0.0 1.8 1 1 1 2 2 2 0 Talin, middle domain SOUL PF04832.12 KFM75209.1 - 3.1e-35 121.8 0.0 3.7e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein NTS PF15447.6 KFM75210.1 - 0.0089 16.5 0.3 0.02 15.4 0.3 1.6 1 0 0 1 1 1 1 N-terminal segments of PfEMP1 zf-C2H2 PF00096.26 KFM75211.1 - 0.00038 20.7 2.4 0.00038 20.7 2.4 4.0 4 1 0 4 4 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM75211.1 - 0.001 19.3 0.3 0.001 19.3 0.3 4.3 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFM75211.1 - 0.0012 19.5 25.3 0.0081 16.9 1.9 4.1 4 0 0 4 4 3 2 C2H2-type zinc finger zf-met PF12874.7 KFM75211.1 - 0.0026 18.1 19.5 0.0095 16.3 0.2 4.0 4 0 0 4 4 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFM75211.1 - 0.0079 16.6 23.0 0.28 11.7 0.6 4.7 5 0 0 5 5 4 3 Zinc-finger double domain zf_UBZ PF18439.1 KFM75211.1 - 0.014 14.9 6.9 5.5 6.7 0.0 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM75211.1 - 0.034 14.5 0.7 0.034 14.5 0.7 3.6 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.16 KFM75211.1 - 0.038 14.3 20.5 0.44 10.9 1.3 4.6 3 1 2 5 5 5 0 C1 domain HypA PF01155.19 KFM75211.1 - 0.042 13.9 8.9 0.058 13.4 3.1 2.7 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2256 PF10013.9 KFM75211.1 - 0.056 13.6 6.7 7.6 6.7 0.2 3.8 4 0 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-BED PF02892.15 KFM75211.1 - 0.058 13.4 0.8 0.058 13.4 0.8 3.0 3 0 0 3 3 3 0 BED zinc finger Cript PF10235.9 KFM75211.1 - 0.072 13.7 6.8 2.5 8.7 6.8 2.6 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zf-C2H2_6 PF13912.6 KFM75211.1 - 0.087 12.8 0.7 0.087 12.8 0.7 3.7 4 0 0 4 4 3 0 C2H2-type zinc finger Evr1_Alr PF04777.13 KFM75211.1 - 0.23 11.9 7.7 2.2 8.8 0.6 2.7 1 1 1 2 2 2 0 Erv1 / Alr family zf-MYST PF17772.1 KFM75211.1 - 0.29 10.8 0.2 0.29 10.8 0.2 3.0 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2H2_12 PF18658.1 KFM75211.1 - 0.42 10.2 5.5 1.2 8.7 1.2 2.7 1 1 2 3 3 3 0 Zinc-finger C2H2-type zf-trcl PF13451.6 KFM75211.1 - 0.46 10.4 6.4 6.9 6.7 0.1 3.5 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-C2H2_9 PF16293.5 KFM75211.1 - 1.4 8.9 6.6 4.4 7.2 0.1 3.4 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) TF_Zn_Ribbon PF08271.12 KFM75211.1 - 2.9 7.5 9.3 5.1 6.7 3.5 2.8 1 1 1 2 2 2 0 TFIIB zinc-binding zinc_ribbon_15 PF17032.5 KFM75211.1 - 3.4 8.5 12.5 0.075 13.8 3.5 2.6 3 1 0 3 3 3 0 zinc-ribbon family zf-CHY PF05495.12 KFM75211.1 - 4.1 8.0 17.7 0.37 11.3 9.7 2.9 2 2 0 2 2 2 0 CHY zinc finger Ribosomal_L28e PF01778.17 KFM75212.1 - 2.1e-37 128.4 0.8 2.1e-37 128.4 0.8 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KFM75212.1 - 3.4e-29 101.4 19.3 3.4e-29 101.4 19.3 2.3 1 1 1 2 2 2 1 Mak16 protein C-terminal region Astro_capsid_p PF12226.8 KFM75212.1 - 1.7 7.7 11.6 3.4 6.7 11.6 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein An_peroxidase PF03098.15 KFM75213.1 - 9.2e-21 74.0 0.3 1.2e-20 73.7 0.3 1.1 1 0 0 1 1 1 1 Animal haem peroxidase TPP1 PF10341.9 KFM75213.1 - 0.028 14.4 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD VWC PF00093.18 KFM75213.1 - 0.63 10.4 7.2 1.7 9.0 7.2 1.9 1 0 0 1 1 1 0 von Willebrand factor type C domain An_peroxidase PF03098.15 KFM75214.1 - 7.4e-19 67.7 0.0 8e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 KFM75215.1 - 5.1e-34 117.7 0.0 5.6e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 KFM75216.1 - 1.7e-37 129.2 0.0 1.9e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Hydrolase_4 PF12146.8 KFM75217.1 - 0.0053 16.1 0.0 0.022 14.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFM75217.1 - 0.038 14.1 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain HTH_Tnp_Tc3_2 PF01498.18 KFM75218.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75218.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75218.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75218.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75218.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ldl_recept_a PF00057.18 KFM75219.1 - 1.1e-81 268.7 155.9 1e-12 48.0 9.8 9.7 9 0 0 9 9 9 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFM75219.1 - 1.1e-33 115.4 19.1 4.5e-05 23.8 0.1 10.5 10 0 0 10 10 10 7 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFM75219.1 - 1.3e-18 67.0 107.1 1.1e-06 28.8 6.7 8.9 8 0 0 8 8 8 5 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFM75219.1 - 2.7e-12 46.7 18.3 7.9e-10 38.8 4.9 12.0 8 3 4 12 12 12 3 Calcium-binding EGF domain SGL PF08450.12 KFM75219.1 - 3.1e-10 40.1 2.3 0.00046 19.9 0.0 5.0 3 2 2 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 KFM75219.1 - 1.2e-09 37.8 0.8 0.00014 21.2 0.1 3.8 2 2 0 3 3 3 2 Domain of unknown function (DUF5050) cEGF PF12662.7 KFM75219.1 - 1.5e-05 24.9 40.4 0.00087 19.2 0.6 8.1 7 0 0 7 7 7 3 Complement Clr-like EGF-like Arylesterase PF01731.20 KFM75219.1 - 0.0096 16.1 1.3 28 5.0 0.1 5.0 6 0 0 6 6 6 0 Arylesterase EGF_3 PF12947.7 KFM75219.1 - 0.015 15.4 6.7 0.015 15.4 6.7 10.4 11 3 2 13 13 13 0 EGF domain hEGF PF12661.7 KFM75219.1 - 0.034 14.8 1.0 0.034 14.8 1.0 12.0 14 1 1 15 15 15 0 Human growth factor-like EGF Ldl_recept_b PF00058.17 KFM75220.1 - 9.3e-34 115.7 2.4 2.4e-09 37.5 0.0 5.7 5 1 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFM75220.1 - 3.1e-05 24.1 8.5 6.8e-05 23.1 8.5 1.6 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site SGL PF08450.12 KFM75220.1 - 4.4e-05 23.2 1.4 0.17 11.5 0.0 4.1 2 1 1 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region EGF PF00008.27 KFM75220.1 - 0.00013 22.1 6.7 0.00033 20.9 6.7 1.7 1 0 0 1 1 1 1 EGF-like domain cEGF PF12662.7 KFM75220.1 - 0.0057 16.6 2.1 0.014 15.3 2.1 1.8 1 0 0 1 1 1 1 Complement Clr-like EGF-like hEGF PF12661.7 KFM75220.1 - 0.017 15.7 1.3 0.017 15.7 1.3 2.5 2 0 0 2 2 2 0 Human growth factor-like EGF TIL PF01826.17 KFM75220.1 - 0.27 11.5 5.2 0.49 10.7 5.2 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Tme5_EGF_like PF09064.10 KFM75220.1 - 9.2 6.3 6.9 15 5.5 5.0 2.1 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like HTH_Tnp_Tc3_2 PF01498.18 KFM75221.1 - 8.7e-11 41.9 3.6 2e-10 40.8 3.6 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75221.1 - 1.8e-09 37.5 0.0 5.6e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KFM75221.1 - 0.0022 17.6 0.5 0.0065 16.1 0.5 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_12 PF08461.10 KFM75221.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF1656 PF07869.12 KFM75221.1 - 1.1 9.3 4.8 2.6 8.1 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DDE_3 PF13358.6 KFM75222.1 - 1.8e-16 60.2 0.1 3.2e-15 56.2 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75222.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Ig_3 PF13927.6 KFM75223.1 - 3.5e-25 88.4 0.1 3e-13 50.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM75223.1 - 4.1e-21 75.0 0.3 1.2e-09 38.2 0.0 2.9 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFM75223.1 - 6.7e-19 68.0 0.2 4.6e-10 39.7 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM75223.1 - 1.4e-18 66.7 0.0 7.3e-12 45.2 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain V-set PF07686.17 KFM75223.1 - 7.1e-10 39.0 3.5 0.00051 20.2 0.1 4.6 3 3 0 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM75223.1 - 0.00032 20.2 0.0 0.001 18.6 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM75223.1 - 0.012 15.6 0.0 0.17 11.9 0.0 2.5 3 1 0 3 3 3 0 C17orf99 Ig domain Ig_5 PF16681.5 KFM75223.1 - 0.049 14.0 0.0 0.51 10.8 0.0 2.5 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain I-set PF07679.16 KFM75224.1 - 5.8e-11 42.3 0.3 0.00022 21.2 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM75224.1 - 3.6e-08 33.9 0.5 0.0079 16.8 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM75224.1 - 4.1e-06 27.0 0.1 0.068 13.5 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM75224.1 - 2.2e-05 24.6 0.1 0.17 12.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 KFM75224.1 - 6.7e-05 23.0 0.1 0.15 12.3 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM75224.1 - 0.13 12.3 0.0 0.83 9.7 0.0 1.9 2 0 0 2 2 2 0 C17orf99 Ig domain Ig_3 PF13927.6 KFM75225.1 - 3.9e-35 120.3 2.3 8.7e-14 51.9 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 KFM75225.1 - 5.3e-34 116.2 0.1 3.8e-14 52.5 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain ig PF00047.25 KFM75225.1 - 4.4e-23 81.3 0.4 5.4e-08 32.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain fn3 PF00041.21 KFM75225.1 - 4.8e-19 68.5 0.8 2.4e-18 66.2 0.7 2.2 2 0 0 2 2 2 1 Fibronectin type III domain Ig_2 PF13895.6 KFM75225.1 - 6.8e-18 64.8 0.1 1.2e-06 28.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM75225.1 - 7.3e-13 48.7 3.6 6.4e-05 23.1 0.0 5.4 4 2 0 4 4 4 2 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFM75225.1 - 5.3e-08 33.3 0.1 1.5e-07 31.8 0.1 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Ig_5 PF16681.5 KFM75225.1 - 2.2e-06 28.0 0.1 0.19 12.2 0.0 4.0 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM75225.1 - 4.8e-06 26.5 0.2 0.19 11.8 0.0 3.1 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM75225.1 - 1e-05 25.0 0.0 0.0038 16.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM75225.1 - 0.00034 20.6 1.8 0.93 9.6 0.1 4.5 5 2 0 5 5 5 1 C17orf99 Ig domain V-set_CD47 PF08204.11 KFM75225.1 - 0.00062 19.8 0.0 1.1 9.3 0.0 3.6 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain SusE PF14292.6 KFM75225.1 - 0.0023 18.1 0.2 0.0063 16.7 0.2 1.8 1 0 0 1 1 1 1 SusE outer membrane protein C1-set PF07654.15 KFM75225.1 - 0.027 14.8 0.0 0.67 10.4 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin C1-set domain EphA2_TM PF14575.6 KFM75227.1 - 0.0066 17.3 0.0 0.0088 16.9 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 KFM75227.1 - 0.018 15.7 0.0 0.041 14.6 0.0 1.7 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 KFM75227.1 - 0.019 14.9 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family ECSCR PF15820.5 KFM75227.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator fn3 PF00041.21 KFM75227.1 - 0.026 14.9 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain DAG1 PF05454.11 KFM75227.1 - 0.031 13.7 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Sarcoglycan_2 PF05510.13 KFM75227.1 - 0.16 10.7 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon HTH_Tnp_Tc3_2 PF01498.18 KFM75229.1 - 1.3e-17 63.7 1.5 5.1e-16 58.7 2.2 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75229.1 - 1.1e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75230.1 - 3.9e-16 59.1 3.0 6.4e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75230.1 - 1.5e-13 50.7 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75230.1 - 3.1e-07 30.0 1.6 7.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75230.1 - 0.0028 17.4 0.6 0.0083 15.9 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75230.1 - 2.8 8.6 15.6 0.14 12.8 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DUF1759 PF03564.15 KFM75231.1 - 1.6e-33 115.7 0.8 1.6e-33 115.7 0.8 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1759) CHASE3 PF05227.13 KFM75231.1 - 0.0066 16.4 0.5 0.18 11.7 0.2 2.4 2 0 0 2 2 2 1 CHASE3 domain DUF3258 PF11646.8 KFM75231.1 - 0.04 14.0 2.7 0.13 12.4 2.7 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF3258 CLZ PF16526.5 KFM75231.1 - 1.8 8.9 6.6 0.99 9.8 2.2 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HTH_Tnp_Tc3_2 PF01498.18 KFM75232.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75232.1 - 1.9e-14 53.6 0.0 3.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Fructosamin_kin PF03881.14 KFM75233.1 - 1.5e-17 63.7 0.0 1.6e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFM75233.1 - 0.0033 17.4 0.0 0.0036 17.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFM75233.1 - 0.013 15.1 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Gln-synt_N PF03951.19 KFM75233.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Fructosamin_kin PF03881.14 KFM75234.1 - 3.2e-20 72.5 0.2 3.4e-20 72.4 0.2 1.0 1 0 0 1 1 1 1 Fructosamine kinase zf-C3HC4_3 PF13920.6 KFM75235.1 - 1.2e-06 28.3 6.3 2.3e-06 27.3 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM75235.1 - 1.5e-06 27.9 8.6 3.4e-06 26.8 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM75235.1 - 2e-05 24.5 7.2 0.00024 21.1 4.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFM75235.1 - 2.5e-05 24.5 10.2 6e-05 23.3 10.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM75235.1 - 8.4e-05 22.5 6.7 0.0002 21.3 6.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM75235.1 - 0.00017 21.4 8.4 0.00047 19.9 8.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM75235.1 - 0.015 15.1 6.7 0.036 13.9 6.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFM75235.1 - 0.035 14.3 9.0 0.095 12.9 9.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFM75235.1 - 4.8 7.6 8.1 15 6.0 8.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Wyosine_form PF08608.12 KFM75236.1 - 2.4e-26 91.8 0.0 8.2e-26 90.2 0.0 2.0 2 0 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.21 KFM75236.1 - 9.2e-26 91.2 0.0 2.2e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KFM75236.1 - 1.3e-22 80.6 0.0 3e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin Hydrolase PF00702.26 KFM75236.1 - 0.085 13.1 0.0 0.5 10.6 0.0 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Spb1_C PF07780.12 KFM75237.1 - 2.5e-38 131.8 20.9 2.8e-38 131.7 20.9 1.0 1 0 0 1 1 1 1 Spb1 C-terminal domain DUF148 PF02520.17 KFM75237.1 - 0.00017 21.7 1.8 0.00022 21.3 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF1859 PF08948.10 KFM75237.1 - 0.18 11.7 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) ResB PF05140.14 KFM75237.1 - 0.5 9.1 3.5 0.62 8.7 3.5 1.0 1 0 0 1 1 1 0 ResB-like family DUF3987 PF13148.6 KFM75237.1 - 4.2 6.3 6.9 5.2 6.0 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) HTH_Tnp_Tc3_2 PF01498.18 KFM75240.1 - 2e-16 60.0 2.2 5e-16 58.7 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75240.1 - 1.1e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_48 PF17906.1 KFM75240.1 - 3.3e-10 39.9 0.0 6.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase An_peroxidase PF03098.15 KFM75241.1 - 6.2e-59 200.0 0.0 6.9e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 KFM75242.1 - 5.8e-77 259.5 0.0 6.4e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 KFM75243.1 - 4.4e-06 25.5 0.4 6.2e-06 25.1 0.4 1.2 1 0 0 1 1 1 1 Animal haem peroxidase DUF1189 PF06691.11 KFM75243.1 - 0.17 11.4 2.3 0.18 11.4 1.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1189) Neurokinin_B PF03823.14 KFM75244.1 - 1.6 8.8 5.5 2.6 8.1 5.5 1.6 1 1 0 1 1 1 0 Neurokinin B GILT PF03227.16 KFM75245.1 - 6.7e-17 61.7 0.1 1.2e-16 60.9 0.0 1.4 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Aldo_ket_red PF00248.21 KFM75246.1 - 5.5e-10 38.9 0.0 5.9e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_Tc3_2 PF01498.18 KFM75247.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75247.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Prenylcys_lyase PF07156.14 KFM75248.1 - 5.9e-111 371.1 0.6 7.1e-111 370.8 0.6 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KFM75248.1 - 2.2e-08 34.2 0.1 4.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFM75248.1 - 2.3e-06 27.2 0.0 5.6e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KFM75248.1 - 0.00018 20.9 0.1 0.0049 16.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFM75248.1 - 0.00033 20.3 0.5 0.00059 19.5 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFM75248.1 - 0.033 13.0 0.1 0.052 12.4 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TFIIF_alpha PF05793.12 KFM75249.1 - 2.8e-141 471.7 68.1 3.8e-141 471.3 68.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3874 PF12990.7 KFM75249.1 - 0.099 13.0 0.1 0.36 11.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) F-box-like PF12937.7 KFM75250.1 - 1.4e-12 47.3 0.9 1.6e-12 47.1 0.9 1.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM75250.1 - 4.3e-10 39.2 1.4 4.9e-10 39.0 1.4 1.1 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KFM75251.1 - 1.7e-06 28.2 2.7 0.0045 17.4 0.2 3.9 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM75251.1 - 6.2e-06 25.9 1.1 0.38 10.9 0.0 5.4 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.6 KFM75251.1 - 1.1e-05 25.1 0.3 0.024 14.4 0.0 3.4 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KFM75251.1 - 0.007 16.7 4.3 3 8.7 0.1 5.0 5 1 0 5 5 5 1 Leucine Rich Repeat PIH1 PF08190.12 KFM75252.1 - 9.7e-40 135.7 0.7 9.7e-40 135.7 0.7 1.5 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 KFM75252.1 - 8e-17 61.5 0.1 1.6e-16 60.5 0.1 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain WcbI PF18588.1 KFM75252.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI HTH_Tnp_Tc3_2 PF01498.18 KFM75253.1 - 2.9e-16 59.4 3.3 4.9e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75253.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Prefoldin_2 PF01920.20 KFM75254.1 - 1.1e-17 64.0 1.3 1.2e-17 63.8 1.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF641 PF04859.12 KFM75254.1 - 0.0013 19.0 0.6 0.0017 18.7 0.6 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Prefoldin PF02996.17 KFM75254.1 - 0.0032 17.4 0.5 0.0036 17.2 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Med9 PF07544.13 KFM75254.1 - 0.0092 16.0 0.6 0.0092 16.0 0.6 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Nup88 PF10168.9 KFM75254.1 - 0.019 12.8 0.3 0.019 12.8 0.3 1.0 1 0 0 1 1 1 0 Nuclear pore component SMC_ScpB PF04079.16 KFM75254.1 - 0.025 14.2 0.3 0.033 13.8 0.3 1.2 1 1 0 1 1 1 0 Segregation and condensation complex subunit ScpB PG_binding_4 PF12229.8 KFM75254.1 - 0.027 14.7 0.1 0.044 14.1 0.1 1.4 1 1 0 1 1 1 0 Putative peptidoglycan binding domain Abhydrolase_6 PF12697.7 KFM75256.1 - 1.8e-08 35.3 0.0 3.8e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM75256.1 - 3.6e-08 33.0 0.0 3.6e-06 26.4 0.0 2.6 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM75256.1 - 5.2e-08 32.9 0.1 3.4e-07 30.2 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold HupE_UreJ PF04955.12 KFM75256.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 HupE / UreJ protein HTH_Tnp_Tc3_2 PF01498.18 KFM75258.1 - 4.8e-16 58.8 4.0 6.1e-16 58.4 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM75258.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75258.1 - 3.2e-07 30.0 1.6 7.5e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75258.1 - 0.003 17.3 0.6 0.008 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75258.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain PRIMA1 PF16101.5 KFM75260.1 - 3.1 7.9 9.3 5.9 7.0 9.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Tox-GHH PF15636.6 KFM75263.1 - 8e-26 89.8 0.1 1.9e-25 88.7 0.1 1.7 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin RHS_repeat PF05593.14 KFM75263.1 - 1.6e-07 31.6 27.0 0.19 12.3 0.1 9.8 9 1 0 9 9 9 4 RHS Repeat RHS PF03527.14 KFM75263.1 - 0.0098 15.6 0.0 0.031 14.0 0.0 1.9 1 0 0 1 1 1 1 RHS protein DEAD_assoc PF08494.11 KFM75263.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 DEAD/H associated RHS_repeat PF05593.14 KFM75264.1 - 1.1e-07 32.2 0.3 0.00017 22.0 0.1 3.2 2 1 1 3 3 3 3 RHS Repeat CHU_C PF13585.6 KFM75264.1 - 0.11 12.6 1.2 0.62 10.1 1.2 2.2 1 1 0 1 1 1 0 C-terminal domain of CHU protein family NHL PF01436.21 KFM75265.1 - 2e-08 33.9 0.0 0.034 14.2 0.0 3.5 3 0 0 3 3 3 3 NHL repeat DUF4573 PF15140.6 KFM75266.1 - 2.7e-07 30.5 7.6 4e-07 30.0 7.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) Torsin PF06309.11 KFM75266.1 - 0.074 13.2 10.9 3.8 7.6 0.4 3.4 1 1 2 3 3 3 0 Torsin RFXA_RFXANK_bdg PF15289.6 KFM75266.1 - 6.8 7.0 31.4 1.8e+04 -14.7 31.4 4.1 1 1 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Ten_N PF06484.12 KFM75269.1 - 0.2 11.5 0.8 0.24 11.3 0.8 1.0 1 0 0 1 1 1 0 Teneurin Intracellular Region HTH_Tnp_Tc3_2 PF01498.18 KFM75270.1 - 3.6e-16 59.2 3.4 6.3e-16 58.4 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM75270.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75270.1 - 3.1e-07 30.0 1.6 7.6e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75270.1 - 0.003 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75270.1 - 2.9 8.6 15.6 0.13 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Forkhead PF00250.18 KFM75273.1 - 2.3e-38 130.3 0.1 4.3e-38 129.4 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain HNF_C PF09354.10 KFM75273.1 - 7.1e-08 33.4 2.8 7.1e-08 33.4 2.8 5.0 3 2 0 3 3 3 1 HNF3 C-terminal domain Forkhead_N PF08430.12 KFM75273.1 - 3.8e-07 30.8 22.0 3.8e-07 30.8 22.0 4.2 3 1 1 4 4 4 1 Forkhead N-terminal region DpnI_C PF17726.1 KFM75273.1 - 0.12 12.5 0.2 0.36 11.0 0.2 1.8 1 0 0 1 1 1 0 Dam-replacing HTH domain Baculo_PEP_C PF04513.12 KFM75275.1 - 5.4e-07 29.7 0.5 0.0011 19.1 0.1 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 KFM75275.1 - 1.3e-06 28.6 22.8 0.00081 19.5 13.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1640) DUF1664 PF07889.12 KFM75275.1 - 0.00022 21.2 20.4 0.0094 16.0 2.6 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 KFM75275.1 - 0.00037 20.4 20.5 0.0012 18.7 20.5 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KFM75275.1 - 0.00067 19.8 20.5 0.12 12.5 8.9 2.3 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) HSBP1 PF06825.12 KFM75275.1 - 0.0051 16.7 2.1 0.073 12.9 0.1 3.0 2 1 1 3 3 3 1 Heat shock factor binding protein 1 DUF883 PF05957.13 KFM75275.1 - 0.0066 17.0 15.0 0.17 12.5 1.6 2.6 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 KFM75275.1 - 0.0066 14.5 11.4 0.0064 14.5 10.2 1.5 1 1 0 1 1 1 1 Prominin Spc7 PF08317.11 KFM75275.1 - 0.0066 15.4 22.2 0.0088 15.0 22.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Spectrin PF00435.21 KFM75275.1 - 0.013 16.0 16.1 0.033 14.7 2.4 2.9 1 1 1 2 2 2 0 Spectrin repeat ApoO PF09769.9 KFM75275.1 - 0.018 15.0 7.4 0.38 10.7 0.9 2.8 1 1 1 2 2 2 0 Apolipoprotein O Golgin_A5 PF09787.9 KFM75275.1 - 0.027 13.9 21.8 0.036 13.5 21.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phasin PF05597.11 KFM75275.1 - 0.04 13.9 21.7 0.11 12.5 5.5 2.6 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tnp_22_trimer PF17489.2 KFM75275.1 - 0.048 13.6 1.1 0.048 13.6 1.1 5.3 2 2 3 5 5 4 0 L1 transposable element trimerization domain FliD_C PF07195.12 KFM75275.1 - 0.063 12.7 7.7 2.2 7.7 1.4 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF3584 PF12128.8 KFM75275.1 - 0.064 10.8 19.0 0.099 10.1 19.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 KFM75275.1 - 0.082 12.3 22.4 0.28 10.5 21.1 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KFM75275.1 - 0.088 13.0 16.0 0.08 13.1 9.5 2.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF2884 PF11101.8 KFM75275.1 - 0.13 11.7 20.0 0.18 11.3 18.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) DUF148 PF02520.17 KFM75275.1 - 0.14 12.2 18.8 1.8 8.7 12.7 3.2 1 1 2 3 3 3 0 Domain of unknown function DUF148 PIN_8 PF18476.1 KFM75275.1 - 0.18 11.7 13.1 0.33 10.8 13.1 1.5 1 1 0 1 1 1 0 PIN like domain COG2 PF06148.11 KFM75275.1 - 0.18 11.9 25.1 0.69 10.0 4.1 3.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.12 KFM75275.1 - 0.25 11.4 22.6 0.07 13.2 17.7 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3994 PF13159.6 KFM75275.1 - 0.25 11.9 2.2 0.52 10.9 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3994) Peptidase_M75 PF09375.10 KFM75275.1 - 0.27 10.7 5.4 0.35 10.3 5.4 1.3 1 1 0 1 1 1 0 Imelysin LacI PF00356.21 KFM75275.1 - 0.27 11.0 3.5 0.82 9.5 0.5 3.0 1 1 1 2 2 2 0 Bacterial regulatory proteins, lacI family DUF4407 PF14362.6 KFM75275.1 - 0.33 10.3 11.7 0.73 9.1 11.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Duo1 PF08651.10 KFM75275.1 - 0.35 10.7 4.9 7.9 6.3 0.2 3.5 1 1 2 4 4 4 0 DASH complex subunit Duo1 NPV_P10 PF05531.12 KFM75275.1 - 0.38 11.2 8.1 0.88 10.1 1.2 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CdvA PF18822.1 KFM75275.1 - 0.42 10.4 24.4 1.3 8.9 2.2 4.0 1 1 3 4 4 4 0 CdvA-like coiled-coil domain FAM184 PF15665.5 KFM75275.1 - 0.45 10.3 27.4 0.14 11.9 17.5 2.1 1 1 0 2 2 2 0 Family with sequence similarity 184, A and B Baculo_p24 PF05073.12 KFM75275.1 - 0.57 10.0 6.6 0.91 9.3 6.5 1.5 1 1 0 1 1 1 0 Baculovirus P24 capsid protein CLZ PF16526.5 KFM75275.1 - 0.67 10.4 18.7 1.3 9.5 0.1 3.5 1 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Strep_SA_rep PF06696.11 KFM75275.1 - 0.88 9.6 5.5 14 5.8 0.1 3.8 2 1 1 3 3 3 0 Streptococcal surface antigen repeat Occludin_ELL PF07303.13 KFM75275.1 - 1.2 9.9 12.2 2.2 9.0 5.1 2.6 1 1 2 3 3 3 0 Occludin homology domain T3SS_needle_F PF09392.10 KFM75275.1 - 1.3 9.3 9.7 6.4 7.1 0.1 4.1 2 2 1 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF HMMR_N PF15905.5 KFM75275.1 - 1.4 8.3 25.6 2.9 7.3 16.9 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CENP-K PF11802.8 KFM75275.1 - 1.5 8.3 18.1 1.6 8.2 17.1 1.5 1 1 0 1 1 1 0 Centromere-associated protein K FlaC_arch PF05377.11 KFM75275.1 - 1.9 9.0 26.5 0.88 10.0 4.8 4.5 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) hDGE_amylase PF14701.6 KFM75275.1 - 2.4 7.2 11.0 2.9 6.9 11.0 1.0 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Exonuc_VII_L PF02601.15 KFM75275.1 - 2.9 7.4 11.5 5.8 6.4 11.5 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin PF00804.25 KFM75275.1 - 3 7.5 25.1 0.39 10.4 11.6 2.6 1 1 2 3 3 3 0 Syntaxin CwsA PF10814.8 KFM75275.1 - 3 8.0 8.1 6.4 7.0 1.0 3.0 1 1 2 3 3 3 0 Cell wall synthesis protein CwsA DUF5082 PF16888.5 KFM75275.1 - 3.3 8.0 16.5 41 4.5 16.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) CAF-1_p150 PF11600.8 KFM75275.1 - 3.5 7.3 25.9 27 4.4 26.6 1.8 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal OmpH PF03938.14 KFM75275.1 - 3.5 8.0 26.3 40 4.5 11.8 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 KFM75275.1 - 5.6 5.9 14.1 0.37 9.8 4.5 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MnmE_helical PF12631.7 KFM75275.1 - 5.6 7.1 10.8 0.83 9.8 0.8 2.4 1 1 1 2 2 2 0 MnmE helical domain Ax_dynein_light PF10211.9 KFM75275.1 - 6.8 6.6 22.9 2.3 8.1 4.6 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Sds3 PF08598.11 KFM75275.1 - 8.3 6.3 12.0 11 5.9 0.7 2.2 2 0 0 2 2 2 0 Sds3-like Allexi_40kDa PF05549.11 KFM75275.1 - 9.6 5.6 6.1 21 4.5 6.1 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein Sulfotransfer_1 PF00685.27 KFM75276.1 - 2.3e-61 207.6 3.2 3.4e-60 203.8 3.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM75276.1 - 5.9e-05 23.5 0.1 0.41 11.0 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family RT_RNaseH_2 PF17919.1 KFM75277.1 - 9.1e-32 109.1 0.0 2e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM75277.1 - 1.2e-29 102.6 0.0 3.1e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM75277.1 - 2.2e-25 89.5 0.1 3.7e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM75277.1 - 3.1e-22 79.0 0.0 7.6e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM75277.1 - 2.8e-19 69.0 0.3 5.5e-19 68.0 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KFM75277.1 - 3.1e-05 23.7 0.0 7.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KFM75277.1 - 3.3e-05 24.0 0.1 8.7e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 KFM75277.1 - 0.0005 20.6 0.0 0.0017 18.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM75277.1 - 0.0068 17.0 0.0 0.019 15.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 KFM75277.1 - 0.011 15.7 0.3 0.026 14.6 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Topoisom_I_N PF02919.15 KFM75277.1 - 4.2 6.8 6.6 1.2 8.6 2.0 2.3 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RVT_1 PF00078.27 KFM75278.1 - 2.2e-05 24.1 0.1 4e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2634 PF10934.8 KFM75278.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) DUF5641 PF18701.1 KFM75279.1 - 1.3e-25 89.4 0.1 2.8e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1759 PF03564.15 KFM75279.1 - 3.7e-23 82.1 0.1 8.1e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM75279.1 - 1.7e-08 34.4 0.0 4.1e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 KFM75279.1 - 8.8e-05 23.1 0.0 0.0016 19.1 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM75279.1 - 0.0073 16.8 0.0 0.039 14.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease XFP PF03894.15 KFM75279.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase RNase_H PF00075.24 KFM75280.1 - 7.1e-18 65.2 0.1 2.2e-17 63.6 0.1 1.8 1 0 0 1 1 1 1 RNase H rve PF00665.26 KFM75280.1 - 7.9e-05 22.8 0.0 0.00021 21.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-RVT PF13966.6 KFM75280.1 - 0.053 14.2 0.1 0.12 13.1 0.1 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KFM75281.1 - 0.0046 16.5 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KFM75282.1 - 0.0093 16.0 0.8 0.0093 16.0 0.8 3.1 4 0 0 4 4 4 1 Zinc knuckle LAGLIDADG_WhiA PF14527.6 KFM75282.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain CwsA PF10814.8 KFM75282.1 - 0.052 13.7 0.3 0.091 12.9 0.3 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA zf-CCHC_4 PF14392.6 KFM75282.1 - 0.086 12.6 0.3 0.086 12.6 0.3 3.2 4 0 0 4 4 4 0 Zinc knuckle Sulfotransfer_1 PF00685.27 KFM75284.1 - 8.6e-60 202.5 2.7 1e-58 198.9 2.7 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM75284.1 - 1.6e-05 25.4 0.0 0.016 15.6 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM75286.1 - 2.5e-53 181.3 0.0 3.2e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM75286.1 - 4.4e-06 27.2 0.0 0.006 17.0 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM75287.1 - 4.1e-15 56.0 0.0 5.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM75287.1 - 0.072 13.5 0.0 1.9 8.8 0.0 2.1 1 1 1 2 2 2 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM75288.1 - 1.6e-07 31.1 0.1 5e-07 29.5 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Tox-ODYAM1 PF15642.6 KFM75288.1 - 0.013 14.6 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus RT_RNaseH PF17917.1 KFM75290.1 - 1.1e-24 86.7 0.0 2.4e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KFM75290.1 - 6.2e-22 77.5 0.1 1.2e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1062 PF06353.12 KFM75290.1 - 0.0095 16.8 0.8 0.0095 16.8 0.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1062) gag-asp_proteas PF13975.6 KFM75290.1 - 0.2 12.3 0.0 0.45 11.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_1 PF03184.19 KFM75291.1 - 1e-15 57.8 0.0 1.7e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM75291.1 - 6.4e-12 45.3 0.5 1.4e-11 44.2 0.5 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Sulfotransfer_1 PF00685.27 KFM75292.1 - 1.2e-59 202.0 2.1 5.2e-59 199.9 2.1 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM75292.1 - 1.5e-06 28.8 0.0 0.011 16.1 0.0 2.6 1 1 0 2 2 2 2 Sulfotransferase family ERAP1_C PF11838.8 KFM75292.1 - 0.035 13.6 0.1 3.1 7.3 0.0 2.0 1 1 0 2 2 2 0 ERAP1-like C-terminal domain Sulfotransfer_1 PF00685.27 KFM75293.1 - 1.4e-43 149.4 0.1 2.3e-43 148.6 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM75293.1 - 7.1e-05 23.3 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family HTH_Tnp_Tc3_2 PF01498.18 KFM75294.1 - 2.3e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75294.1 - 9.7e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Arfaptin PF06456.13 KFM75295.1 - 4.3e-75 252.2 11.4 5.3e-75 251.9 11.4 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR_3 PF16746.5 KFM75295.1 - 0.00022 21.0 11.2 0.00032 20.5 11.2 1.3 1 0 0 1 1 1 1 BAR domain of APPL family HTH_Tnp_4 PF13613.6 KFM75297.1 - 0.0027 17.4 0.1 0.0064 16.2 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75298.1 - 4.1e-10 39.7 0.7 1.1e-09 38.4 0.7 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75298.1 - 1.2e-09 38.1 0.0 4.8e-09 36.1 0.0 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_1 PF11427.8 KFM75298.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Tc3 transposase Phage_int_SAM_6 PF18644.1 KFM75298.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain HTH_38 PF13936.6 KFM75298.1 - 0.53 10.1 3.6 4.3 7.2 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM75299.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75299.1 - 8.4e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Sulfotransfer_1 PF00685.27 KFM75300.1 - 1.7e-49 168.7 1.5 1.1e-48 166.1 1.5 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM75300.1 - 0.0013 19.1 0.0 0.14 12.5 0.0 2.5 2 1 0 2 2 2 2 Sulfotransferase family SCAN PF02023.17 KFM75301.1 - 2e-09 37.1 0.4 6.9e-09 35.4 0.4 1.9 1 0 0 1 1 1 1 SCAN domain zf-CCHC PF00098.23 KFM75301.1 - 0.09 12.9 2.3 0.21 11.7 2.3 1.7 1 0 0 1 1 1 0 Zinc knuckle DDE_3 PF13358.6 KFM75302.1 - 3.7e-16 59.2 0.1 4.2e-15 55.8 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75302.1 - 1.2e-10 41.5 1.0 3.1e-10 40.2 1.0 1.8 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM75303.1 - 1.2e-17 64.0 1.2 2.1e-17 63.1 1.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75303.1 - 4e-05 23.4 0.0 0.001 18.9 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM75303.1 - 0.002 18.7 0.7 0.002 18.7 0.7 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 KFM75303.1 - 0.081 12.6 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Glyco_hydro_12 PF01670.16 KFM75304.1 - 0.017 15.1 0.1 0.02 14.9 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 HTH_Tnp_Tc3_2 PF01498.18 KFM75305.1 - 4.2e-16 59.0 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75305.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75305.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75305.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75305.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM75306.1 - 0.023 14.4 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Ig_3 PF13927.6 KFM75310.1 - 3.1e-17 62.9 0.3 1.3e-07 32.1 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM75310.1 - 5.8e-17 61.5 0.0 4.2e-08 33.2 0.0 2.3 2 1 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFM75310.1 - 5.7e-15 55.4 0.1 4.2e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM75310.1 - 2.5e-10 40.6 0.0 3.2e-05 24.2 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM75310.1 - 5.5e-05 23.3 0.1 0.49 10.6 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM75310.1 - 0.002 18.2 0.0 0.0049 16.9 0.0 1.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM75311.1 - 1.8e-16 60.1 2.2 6.5e-16 58.3 2.2 2.0 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75311.1 - 1.4e-13 50.8 0.0 2.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75311.1 - 3.1e-07 30.0 1.6 7.8e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75311.1 - 0.003 17.3 0.6 0.0085 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75311.1 - 3 8.5 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain SSF PF00474.17 KFM75312.1 - 3.6e-104 348.9 19.7 2.9e-93 312.9 7.3 2.2 1 1 1 2 2 2 2 Sodium:solute symporter family HTH_Tnp_Tc3_2 PF01498.18 KFM75312.1 - 2.8e-15 56.3 6.5 9.6e-15 54.6 6.5 2.0 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75312.1 - 1.5e-14 53.9 0.1 6e-14 52.0 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease Arc_C PF18162.1 KFM75312.1 - 0.00013 21.7 0.6 0.00035 20.4 0.6 1.7 1 0 0 1 1 1 1 Arc C-lobe HTH_32 PF13565.6 KFM75312.1 - 0.0046 17.6 1.5 0.0046 17.6 1.5 2.9 3 0 0 3 3 3 1 Homeodomain-like domain PIRT PF15099.6 KFM75312.1 - 0.019 14.5 1.1 0.046 13.3 1.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family HTH_29 PF13551.6 KFM75312.1 - 0.059 13.4 0.2 0.19 11.8 0.2 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 KFM75312.1 - 0.074 12.9 0.2 0.61 10.0 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Retrotrans_gag PF03732.17 KFM75312.1 - 0.11 12.7 0.1 1.8 8.9 0.0 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein MnmE_helical PF12631.7 KFM75312.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 MnmE helical domain Gluconate_2-dh3 PF13618.6 KFM75313.1 - 0.02 15.2 0.3 0.024 14.9 0.3 1.2 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 SRI PF08236.11 KFM75313.1 - 0.15 12.3 2.4 0.26 11.5 2.4 1.4 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Skp1 PF01466.19 KFM75314.1 - 1.6e-29 101.7 0.7 3.2e-29 100.8 0.7 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KFM75314.1 - 1.4e-27 95.6 0.7 2.9e-27 94.6 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 KFM75314.1 - 0.036 14.3 0.0 0.6 10.4 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain KH_1 PF00013.29 KFM75315.1 - 6.9e-25 86.7 3.8 1e-15 57.3 1.4 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KFM75315.1 - 4e-08 33.0 0.3 0.0014 18.4 0.3 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 KFM75315.1 - 1.5e-05 25.0 2.7 0.012 15.7 0.2 2.5 2 0 0 2 2 2 2 NusA-like KH domain KH_4 PF13083.6 KFM75315.1 - 2.4e-05 24.1 0.2 0.0082 16.0 0.2 2.3 2 0 0 2 2 2 2 KH domain RTX_C PF08339.10 KFM75315.1 - 0.00091 19.3 0.6 0.0017 18.4 0.6 1.4 1 0 0 1 1 1 1 RTX C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM75316.1 - 2.8e-14 53.1 1.2 6.6e-14 51.9 0.5 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75316.1 - 4.6e-06 26.4 0.0 6.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Harakiri PF15196.6 KFM75316.1 - 0.15 12.5 5.1 0.34 11.4 5.1 1.6 1 0 0 1 1 1 0 Activator of apoptosis harakiri Sprouty PF05210.13 KFM75318.1 - 7.6e-27 93.7 33.1 1.2e-26 93.0 33.1 1.4 1 0 0 1 1 1 1 Sprouty protein (Spry) RT_RNaseH_2 PF17919.1 KFM75319.1 - 0.085 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase UQ_con PF00179.26 KFM75320.1 - 0.0074 15.9 0.0 0.0076 15.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ANF_receptor PF01094.28 KFM75321.1 - 5.7e-15 55.3 0.0 6.1e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region DUF4932 PF16286.5 KFM75321.1 - 0.022 14.0 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) Lig_chan-Glu_bd PF10613.9 KFM75322.1 - 1.7e-20 73.3 0.1 1.9e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site MA3 PF02847.17 KFM75322.1 - 0.083 12.9 0.3 0.22 11.5 0.1 1.6 2 0 0 2 2 2 0 MA3 domain Lig_chan PF00060.26 KFM75323.1 - 5.5e-55 185.3 0.6 7.1e-55 184.9 0.6 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 KFM75323.1 - 4.6e-08 32.8 0.0 6.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HTH_Tnp_Tc3_2 PF01498.18 KFM75324.1 - 5e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75324.1 - 7.2e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75324.1 - 3e-07 30.1 0.8 7.1e-07 28.9 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75324.1 - 0.0028 17.4 0.6 0.0076 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75324.1 - 2.5 8.8 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Lig_chan PF00060.26 KFM75325.1 - 1.1e-43 148.6 0.2 1.8e-43 147.9 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFM75325.1 - 2.1e-42 143.9 0.1 5e-42 142.7 0.1 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM75325.1 - 6.2e-23 81.4 0.0 1.5e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFM75325.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 0 Receptor family ligand binding region NQR2_RnfD_RnfE PF03116.15 KFM75325.1 - 0.07 12.5 0.1 0.07 12.5 0.1 1.7 2 0 0 2 2 2 0 NQR2, RnfD, RnfE family Sterile PF03015.19 KFM75325.1 - 0.088 13.0 0.3 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein ANF_receptor PF01094.28 KFM75326.1 - 5.3e-05 22.5 0.1 5.6e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region VirE1 PF12189.8 KFM75326.1 - 0.058 13.5 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Single-strand DNA-binding protein Transposase_1 PF01359.18 KFM75328.1 - 2.3e-11 43.4 0.1 6.3e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 KFM75328.1 - 3.5e-07 30.2 0.1 9.4e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM75328.1 - 3.7e-05 24.2 1.2 3.7e-05 24.2 1.2 3.3 2 1 1 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM75328.1 - 0.00012 22.0 6.4 0.018 15.1 0.1 3.9 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 KFM75328.1 - 0.00014 21.9 7.0 0.0019 18.3 0.6 3.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75328.1 - 0.001 18.8 7.3 0.036 13.9 0.6 3.5 3 1 0 3 3 3 2 Homeodomain-like domain HTH_24 PF13412.6 KFM75328.1 - 0.004 16.7 0.0 0.02 14.5 0.0 2.2 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KFM75328.1 - 0.05 13.4 1.2 0.16 11.8 0.1 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_7 PF02796.15 KFM75328.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DDE_3 PF13358.6 KFM75329.1 - 4.6e-16 58.9 0.1 5.6e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75329.1 - 7.7e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM75329.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM75329.1 - 0.0024 17.6 0.1 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75329.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM75329.1 - 0.032 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix I-set PF07679.16 KFM75330.1 - 2.4e-41 139.7 0.0 3.2e-14 52.8 0.0 4.9 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM75330.1 - 4.7e-39 132.9 0.3 5.3e-12 46.2 0.0 4.7 5 0 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 KFM75330.1 - 1e-26 93.0 0.0 3.4e-08 33.7 0.0 4.2 3 1 1 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFM75330.1 - 4.2e-26 90.9 0.0 5.9e-08 32.8 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain fn3 PF00041.21 KFM75330.1 - 1e-18 67.4 0.0 2.7e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain V-set PF07686.17 KFM75330.1 - 7e-14 51.9 2.3 0.00017 21.7 0.0 5.6 4 2 0 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM75330.1 - 4.6e-08 32.5 0.0 0.015 14.9 0.0 4.0 4 0 0 4 4 4 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM75330.1 - 6.4e-07 29.9 0.0 5.3e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 KFM75330.1 - 4e-05 23.6 0.0 4.3 7.5 0.0 4.4 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFM75330.1 - 0.00012 22.1 0.0 0.11 12.6 0.0 3.4 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFM75330.1 - 0.00014 21.8 0.1 3 7.9 0.0 4.7 3 3 0 3 3 3 2 C17orf99 Ig domain Ig_5 PF16681.5 KFM75330.1 - 0.0012 19.2 0.0 0.22 12.0 0.0 3.5 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set_CD47 PF08204.11 KFM75330.1 - 0.002 18.1 0.1 3.1 7.8 0.0 3.4 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Receptor_2B4 PF11465.8 KFM75330.1 - 0.0075 16.5 0.0 7.7 6.8 0.0 3.5 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 PhoD_N PF16655.5 KFM75330.1 - 0.021 15.4 0.0 0.077 13.5 0.0 1.9 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain DUF2369 PF10179.9 KFM75330.1 - 0.035 14.5 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 KFM75331.1 - 1.6e-12 47.6 0.0 7.1e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain RCR PF12273.8 KFM75331.1 - 0.00027 21.6 0.1 0.00054 20.6 0.1 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red LRRC37AB_C PF14914.6 KFM75331.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Aa_trans PF01490.18 KFM75332.1 - 0.001 17.9 11.7 0.054 12.2 0.3 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein APC_r PF05923.12 KFM75332.1 - 0.024 14.3 0.3 0.054 13.2 0.3 1.6 1 0 0 1 1 1 0 APC repeat Atthog PF18800.1 KFM75332.1 - 2.6 7.9 8.2 3.1 7.7 2.5 2.9 2 1 0 2 2 2 0 Attenuator of Hedgehog THAP PF05485.12 KFM75333.1 - 5.6e-13 49.6 1.1 5.6e-13 49.6 1.1 2.1 2 1 0 2 2 2 1 THAP domain Tn7_Tnp_TnsA_N PF08722.11 KFM75333.1 - 0.003 17.7 0.3 0.006 16.8 0.3 1.5 1 0 0 1 1 1 1 TnsA endonuclease N terminal Zap1_zf2 PF18217.1 KFM75333.1 - 0.0066 16.4 0.3 0.023 14.7 0.3 1.9 1 0 0 1 1 1 1 Zap1 zinc finger 2 IL4_i_Ig PF18258.1 KFM75333.1 - 0.0068 16.6 0.2 3.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Interleukin-4 inducing immunoglobulin-binding domain OCD_Mu_crystall PF02423.15 KFM75334.1 - 7.4e-88 294.5 1.6 8.7e-88 294.3 1.6 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KFM75334.1 - 2e-10 40.8 0.1 3.4e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FTH PF01827.27 KFM75334.1 - 0.0086 15.9 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 FTH domain F420_oxidored PF03807.17 KFM75334.1 - 0.014 15.9 0.1 0.068 13.8 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 KFM75334.1 - 0.025 13.9 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain WD40 PF00400.32 KFM75336.1 - 3e-11 43.7 18.9 0.00017 22.3 0.7 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM75336.1 - 1.5e-10 41.2 0.5 0.28 11.5 0.4 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM75336.1 - 0.00067 19.6 2.0 0.7 9.7 0.1 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFM75336.1 - 0.0038 17.1 0.1 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat POLO_box PF00659.18 KFM75336.1 - 0.0062 16.7 0.2 0.42 10.9 0.1 2.8 2 1 0 2 2 2 1 POLO box duplicated region TSP_1 PF00090.19 KFM75337.1 - 3.4e-07 30.4 2.0 3.4e-07 30.4 2.0 1.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain Clavanin PF05452.11 KFM75338.1 - 0.047 13.9 0.1 0.047 13.9 0.1 1.1 1 0 0 1 1 1 0 Clavanin Kunitz_BPTI PF00014.23 KFM75339.1 - 8e-77 253.4 98.3 2.5e-19 69.2 7.3 10.2 8 0 0 8 8 8 5 Kunitz/Bovine pancreatic trypsin inhibitor domain TatD_DNase PF01026.21 KFM75340.1 - 9.9e-30 103.7 0.0 1.9e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 TatD related DNase CbeA_antitoxin PF06154.11 KFM75340.1 - 0.14 12.8 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A DDE_3 PF13358.6 KFM75341.1 - 5.7e-12 45.6 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Defensin_5 PF18251.1 KFM75341.1 - 0.21 11.7 5.2 0.61 10.2 5.2 1.8 1 0 0 1 1 1 0 Fungal defensin Copsin ANF_receptor PF01094.28 KFM75342.1 - 4.5e-07 29.3 0.0 4.9e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Tubulin PF00091.25 KFM75344.1 - 2.1e-69 233.7 0.0 3.5e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM75344.1 - 2.3e-43 147.3 0.1 3.9e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFM75344.1 - 4.3e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFM75344.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 KFM75344.1 - 0.02 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain ACTH_assoc PF16102.5 KFM75345.1 - 0.94 10.4 0.1 0.94 10.4 0.1 3.4 4 1 1 5 5 5 0 ACTH-associated domain TFIIA PF03153.13 KFM75348.1 - 9.4 6.1 22.4 12 5.8 22.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRP-63 PF14978.6 KFM75349.1 - 0.046 14.3 3.6 0.099 13.3 3.6 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 Nucleo_P87 PF07267.11 KFM75349.1 - 0.5 9.2 5.1 0.63 8.8 5.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HalX PF08663.10 KFM75349.1 - 1.2 9.5 7.2 3.9 7.9 3.1 2.8 2 1 1 3 3 3 0 HalX domain Nucleoporin_N PF08801.11 KFM75352.1 - 4.1e-31 108.2 0.0 4.7e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like COX6C PF02937.15 KFM75353.1 - 4.8e-26 90.7 0.1 5.8e-26 90.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc LicD PF04991.13 KFM75354.1 - 5.9e-16 59.3 11.9 3.2e-12 47.1 2.2 3.6 2 1 1 3 3 3 2 LicD family Torsin PF06309.11 KFM75355.1 - 1.9e-46 157.3 0.2 3.2e-46 156.5 0.2 1.4 1 0 0 1 1 1 1 Torsin AAA_2 PF07724.14 KFM75355.1 - 0.00052 20.2 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFM75355.1 - 0.0024 17.9 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF1270 PF06900.11 KFM75355.1 - 0.69 10.3 3.4 1.6 9.2 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) THAP PF05485.12 KFM75356.1 - 6e-15 55.9 7.6 6.4e-15 55.9 7.6 1.0 1 0 0 1 1 1 1 THAP domain Pet100 PF09803.9 KFM75356.1 - 0.033 14.7 0.0 0.045 14.3 0.0 1.2 1 0 0 1 1 1 0 Pet100 Acyl_transf_3 PF01757.22 KFM75357.1 - 0.07 12.2 3.7 0.072 12.1 3.7 1.0 1 0 0 1 1 1 0 Acyltransferase family DUF3613 PF12266.8 KFM75359.1 - 0.055 13.3 0.1 0.089 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Acyl_transf_3 PF01757.22 KFM75360.1 - 3.3e-10 39.5 1.5 3.6e-10 39.4 1.5 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF229 PF02995.17 KFM75363.1 - 8e-100 334.8 0.6 9.7e-100 334.5 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 KFM75363.1 - 7e-05 22.4 0.2 0.0039 16.6 0.0 2.1 1 1 1 2 2 2 2 Sulfatase RVT_1 PF00078.27 KFM75364.1 - 1.8e-18 66.9 0.0 2.8e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3877 PF12993.7 KFM75364.1 - 0.076 12.9 0.2 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) eIF_4G1 PF12152.8 KFM75365.1 - 0.043 14.0 2.2 1.7 8.9 0.3 2.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 eIF_4EBP PF05456.11 KFM75365.1 - 0.11 12.5 2.7 0.14 12.1 0.5 2.3 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) S1 PF00575.23 KFM75365.1 - 0.21 11.9 2.7 0.48 10.8 2.7 1.5 1 0 0 1 1 1 0 S1 RNA binding domain MAPEG PF01124.18 KFM75366.1 - 6.9e-05 22.7 0.3 7.9e-05 22.6 0.3 1.1 1 0 0 1 1 1 1 MAPEG family MAPEG PF01124.18 KFM75367.1 - 0.0071 16.2 0.0 0.0087 16.0 0.0 1.1 1 0 0 1 1 1 1 MAPEG family GATase_5 PF13507.6 KFM75369.1 - 1.9e-102 341.8 0.0 2.7e-102 341.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KFM75369.1 - 1.5e-35 122.6 0.6 1.3e-20 74.1 0.4 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KFM75369.1 - 9.4e-20 70.7 0.0 1.9e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KFM75369.1 - 1.6e-09 38.1 0.2 4.5e-09 36.7 0.2 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KFM75369.1 - 0.00011 22.8 0.5 0.024 15.3 0.0 2.8 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Nop14 PF04147.12 KFM75370.1 - 0.22 9.7 15.5 0.21 9.8 5.8 2.1 2 0 0 2 2 2 0 Nop14-like family GIT1_C PF12205.8 KFM75370.1 - 0.43 10.7 3.3 2.5 8.2 0.2 2.4 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term CPSF100_C PF13299.6 KFM75370.1 - 1.5 9.0 6.1 2.3 8.4 1.1 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal HTH_Tnp_Tc3_2 PF01498.18 KFM75371.1 - 6.2e-16 58.4 1.4 1.3e-15 57.4 1.4 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75371.1 - 3.1e-11 43.2 0.0 5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM75371.1 - 9.9e-05 22.9 2.2 9.9e-05 22.9 2.2 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KFM75371.1 - 0.056 13.4 0.5 0.74 9.8 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_21 PF13276.6 KFM75371.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 HTH-like domain HTH_3 PF01381.22 KFM75371.1 - 0.13 12.4 1.0 6.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix HTH_28 PF13518.6 KFM75371.1 - 0.51 10.5 2.6 23 5.2 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Dimer_Tnp_hAT PF05699.14 KFM75373.1 - 7.6e-05 22.4 0.1 0.00019 21.2 0.1 1.7 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2726 PF10881.8 KFM75375.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) PWI PF01480.17 KFM75376.1 - 8.5e-28 96.5 0.2 1.8e-27 95.4 0.1 1.7 2 0 0 2 2 2 1 PWI domain RS4NT PF08071.12 KFM75377.1 - 0.11 12.7 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 RS4NT (NUC023) domain DDE_1 PF03184.19 KFM75380.1 - 1.9e-28 99.3 0.5 4e-28 98.2 0.2 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM75380.1 - 1.7e-16 60.0 0.2 1.2e-15 57.3 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain BrkDBD PF09607.10 KFM75380.1 - 0.0025 17.6 0.7 0.007 16.1 0.1 2.1 2 0 0 2 2 2 1 Brinker DNA-binding domain Ribosomal_S13_N PF08069.12 KFM75380.1 - 0.084 12.9 1.5 3.2 7.9 0.1 3.4 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain JHBP PF06585.11 KFM75381.1 - 3.3e-40 137.8 1.3 6.5e-40 136.8 1.1 1.5 2 0 0 2 2 2 1 Haemolymph juvenile hormone binding protein (JHBP) Grp7_allergen PF16984.5 KFM75381.1 - 5.5e-36 124.3 0.7 1.1e-35 123.4 0.1 1.8 2 0 0 2 2 2 1 Group 7 allergen Peptidase_S11 PF00768.20 KFM75381.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase JHBP PF06585.11 KFM75382.1 - 9.9e-36 123.1 0.1 1.2e-35 122.9 0.1 1.0 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) DUF4371 PF14291.6 KFM75383.1 - 5.5e-10 39.3 0.1 2.2e-09 37.3 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM75383.1 - 0.0031 17.1 0.4 0.0031 17.1 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger C2H2-type Renin_r PF07850.14 KFM75384.1 - 0.074 13.7 3.9 0.59 10.8 0.6 2.0 1 1 1 2 2 2 0 Renin receptor-like protein DUF3827 PF12877.7 KFM75384.1 - 3.1 6.1 3.3 2.9 6.1 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3827) TRP PF06011.12 KFM75385.1 - 1.6 7.3 2.9 0.66 8.6 0.1 1.7 2 1 0 2 2 2 0 Transient receptor potential (TRP) ion channel zf-H2C2_2 PF13465.6 KFM75386.1 - 3.1e-106 343.5 105.1 1e-08 35.2 0.6 15.2 15 0 0 15 15 15 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75386.1 - 8.4e-65 211.8 133.5 2.5e-05 24.4 0.4 16.3 16 0 0 16 16 16 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75386.1 - 3.2e-49 161.3 119.7 0.0004 21.0 0.3 15.9 16 0 0 16 16 16 14 C2H2-type zinc finger zf-met PF12874.7 KFM75386.1 - 8.6e-39 130.8 120.8 0.0011 19.3 0.6 16.6 16 0 0 16 16 16 14 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM75386.1 - 1.5e-28 98.4 94.8 0.002 18.4 0.4 16.1 15 2 1 16 16 15 12 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM75386.1 - 1.1e-19 70.0 95.8 0.026 14.5 0.5 15.5 15 0 0 15 15 15 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM75386.1 - 2e-15 56.2 80.8 0.15 11.9 0.3 14.5 14 0 0 14 14 14 10 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM75386.1 - 9.2e-11 41.6 51.9 0.75 9.9 0.1 14.4 9 5 6 15 15 15 4 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 KFM75386.1 - 6.1e-10 38.7 83.4 0.55 10.0 0.7 14.6 15 0 0 15 15 15 8 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM75386.1 - 2e-09 37.1 54.9 0.11 12.4 0.1 14.2 15 0 0 15 15 15 4 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM75386.1 - 6.5e-09 35.9 64.4 0.099 12.7 5.8 6.7 1 1 5 6 6 6 6 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM75386.1 - 3e-07 30.4 56.2 4.1 7.6 0.3 14.9 15 0 0 15 15 15 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM75386.1 - 5.3e-06 26.5 66.3 5.9 7.1 0.3 14.0 14 0 0 14 14 14 1 DBF zinc finger zinc_ribbon_15 PF17032.5 KFM75386.1 - 5.3e-06 27.1 65.9 0.52 11.1 2.2 8.3 4 3 3 8 8 8 6 zinc-ribbon family Tox-HNH-HHH PF15637.6 KFM75386.1 - 6.2e-05 23.1 15.3 3.5 7.8 0.2 6.7 1 1 5 7 7 7 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif GAGA PF09237.11 KFM75386.1 - 7.9e-05 22.4 29.6 3.8 7.4 0.0 9.4 3 2 9 12 12 12 3 GAGA factor A_deaminase PF00962.22 KFM75386.1 - 0.0015 18.0 22.7 1.5 8.1 0.5 5.7 1 1 2 5 5 5 3 Adenosine/AMP deaminase FAM83 PF07894.12 KFM75386.1 - 0.0083 15.7 11.1 11 5.4 0.3 4.5 2 1 2 4 4 4 0 FAM83 A-H Complex1_49kDa PF00346.19 KFM75386.1 - 0.0093 15.1 9.7 0.062 12.4 0.1 3.7 1 1 3 4 4 4 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit C1_1 PF00130.22 KFM75386.1 - 0.014 15.3 87.8 0.027 14.4 4.6 12.8 2 2 9 12 12 12 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 KFM75386.1 - 0.028 14.5 77.1 0.43 10.8 7.2 7.2 1 1 6 8 8 8 0 FYVE zinc finger BolA PF01722.18 KFM75386.1 - 0.041 14.2 26.7 2.1 8.7 1.6 8.5 1 1 7 9 9 9 0 BolA-like protein zf-Dof PF02701.15 KFM75386.1 - 0.93 9.7 49.1 4.6 7.5 0.1 11.6 4 3 9 13 13 13 0 Dof domain, zinc finger NAD_kinase PF01513.21 KFM75386.1 - 1.2 8.2 6.9 30 3.7 1.7 4.5 1 1 1 3 3 3 0 ATP-NAD kinase Zn_ribbon_SprT PF17283.2 KFM75386.1 - 3.8 7.5 47.9 2.7 8.0 0.1 11.1 12 3 2 14 14 14 0 SprT-like zinc ribbon domain Zf_RING PF16744.5 KFM75386.1 - 3.9 7.7 72.6 5.2 7.2 4.2 14.0 2 2 10 12 12 11 0 KIAA1045 RING finger Acyltransf_C PF16076.5 KFM75386.1 - 9.4 6.4 7.4 3.7 7.7 0.6 3.9 4 1 0 4 4 4 0 Acyltransferase C-terminus Vps35 PF03635.17 KFM75387.1 - 1.8e-79 268.1 5.6 2e-79 268.0 5.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF758 PF05527.11 KFM75387.1 - 0.034 14.1 0.2 0.061 13.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Ig_3 PF13927.6 KFM75388.1 - 8.1e-14 52.0 0.2 2.2e-07 31.3 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM75388.1 - 2.2e-13 50.2 0.3 6.8e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM75388.1 - 1.2e-12 47.7 0.1 3.5e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFM75388.1 - 1.4e-10 41.1 0.1 7.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM75388.1 - 2e-09 37.6 0.0 2.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFM75388.1 - 0.025 14.9 0.1 0.073 13.5 0.0 1.8 2 1 1 3 3 3 0 Immunoglobulin C1-set domain zf-RING_4 PF14570.6 KFM75389.1 - 2.9e-14 52.6 11.9 6e-14 51.6 11.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KFM75389.1 - 4.9e-07 29.5 0.0 9.5e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KFM75389.1 - 0.00026 20.8 8.4 0.00088 19.1 8.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KFM75389.1 - 0.081 13.0 6.7 0.55 10.3 1.1 2.7 2 0 0 2 2 2 0 Double zinc ribbon Nup35_RRM_2 PF14605.6 KFM75389.1 - 0.21 11.6 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-ribbon_3 PF13248.6 KFM75389.1 - 0.29 10.6 3.1 15 5.2 0.5 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_5 PF14634.6 KFM75389.1 - 2 8.4 11.8 4.3 7.4 11.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf_C2H2_10 PF18414.1 KFM75389.1 - 2.2 7.9 5.0 8.7 6.0 0.3 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-LITAF-like PF10601.9 KFM75389.1 - 4.4 7.6 9.7 8.8 6.7 6.5 2.5 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Citrate_bind PF16114.5 KFM75390.1 - 2.4e-93 310.5 0.2 4.8e-93 309.6 0.2 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KFM75390.1 - 1.6e-20 73.5 0.0 4.6e-19 68.7 0.0 2.4 1 1 1 2 2 2 1 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KFM75390.1 - 1.1e-15 57.8 0.0 2.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KFM75390.1 - 2.5e-13 50.5 0.0 5.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KFM75390.1 - 2.3e-09 37.1 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KFM75390.1 - 0.0028 17.5 0.0 0.045 13.5 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DUF3524 PF12038.8 KFM75391.1 - 5.4e-64 215.1 0.2 8.4e-64 214.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 KFM75391.1 - 3.9e-11 42.8 0.0 7.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pox_polyA_pol_N PF12630.7 KFM75391.1 - 0.045 14.1 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain ANF_receptor PF01094.28 KFM75392.1 - 3.8e-21 75.6 0.0 4.3e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region RVT_1 PF00078.27 KFM75393.1 - 8.9e-31 107.1 0.1 1.5e-30 106.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM75393.1 - 4.3e-12 45.9 0.1 1.3e-11 44.3 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KFM75393.1 - 9e-09 35.7 0.0 2.1e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 KFM75393.1 - 0.11 11.9 0.3 0.22 11.0 0.3 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family ANF_receptor PF01094.28 KFM75394.1 - 9.6e-25 87.4 0.1 2.2e-24 86.2 0.1 1.6 2 0 0 2 2 2 1 Receptor family ligand binding region zf-CCHC PF00098.23 KFM75394.1 - 0.0078 16.3 3.3 0.014 15.4 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KFM75394.1 - 0.26 11.1 2.0 1.8 8.5 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle SBP_bac_3 PF00497.20 KFM75395.1 - 1e-06 28.4 0.0 1.2e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HTH_Tnp_Tc3_2 PF01498.18 KFM75396.1 - 4.9e-16 58.7 3.5 6e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75396.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75396.1 - 2.2e-07 30.5 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75396.1 - 0.0029 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75396.1 - 0.034 14.3 0.4 0.094 12.9 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM75396.1 - 4.1 8.1 15.0 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain AAA_11 PF13086.6 KFM75397.1 - 2e-29 103.2 1.4 2e-29 103.2 1.4 3.7 3 2 0 3 3 3 1 AAA domain FHA PF00498.26 KFM75397.1 - 2.9e-11 43.5 0.1 1e-10 41.8 0.1 2.0 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM75397.1 - 0.00031 21.0 0.0 0.0012 19.1 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain BTB PF00651.31 KFM75398.1 - 2.5e-18 66.3 0.1 1.5e-17 63.8 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM75398.1 - 0.064 13.4 0.0 0.39 10.9 0.0 2.4 2 0 0 2 2 2 0 BTB And C-terminal Kelch Frag1 PF10277.9 KFM75399.1 - 6.5e-23 81.4 12.8 1.3e-22 80.4 12.8 1.5 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1242 PF06842.12 KFM75399.1 - 0.0027 17.5 0.1 0.0061 16.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DDE_Tnp_1_2 PF13586.6 KFM75399.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain STI1 PF17830.1 KFM75399.1 - 0.55 10.2 4.4 11 6.1 4.4 3.0 1 1 0 1 1 1 0 STI1 domain Voltage_CLC PF00654.20 KFM75399.1 - 0.75 9.0 14.0 0.41 9.8 6.3 2.2 1 1 1 2 2 2 0 Voltage gated chloride channel zf-H2C2_2 PF13465.6 KFM75400.1 - 3.4e-77 251.7 114.2 8.8e-10 38.6 0.9 14.1 13 1 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75400.1 - 1.6e-39 132.1 131.2 6.9e-06 26.2 4.5 12.7 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75400.1 - 7.9e-39 129.0 121.2 8.5e-05 23.1 3.2 12.7 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM75400.1 - 2.6e-21 75.1 99.5 0.0053 16.7 2.1 13.3 12 2 0 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM75400.1 - 2.2e-20 72.4 110.4 0.021 15.2 2.2 12.8 13 0 0 13 13 13 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM75400.1 - 6.1e-09 35.9 94.0 0.0015 18.8 1.5 12.4 11 1 1 12 12 12 6 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM75400.1 - 2.6e-07 30.8 21.2 0.035 14.4 0.1 7.2 3 2 3 7 7 7 2 BolA-like protein DUF4825 PF16107.5 KFM75400.1 - 4.1e-06 26.8 0.0 1.8 8.7 0.0 4.2 2 2 2 4 4 4 1 Domain of unknown function (DUF4825) Ndufs5 PF10200.9 KFM75400.1 - 0.0011 19.2 27.0 0.2 12.0 1.4 5.8 1 1 4 6 6 6 3 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Baculo_IE-1 PF05290.11 KFM75400.1 - 0.005 16.8 43.6 0.39 10.6 4.8 7.5 1 1 4 6 6 6 4 Baculovirus immediate-early protein (IE-0) Complex1_49kDa PF00346.19 KFM75400.1 - 0.12 11.5 0.7 0.78 8.8 0.2 2.3 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-C2HC_2 PF13913.6 KFM75400.1 - 0.12 12.3 56.2 0.57 10.1 0.6 10.6 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFM75400.1 - 9.6 6.1 84.6 0.095 12.5 1.5 11.4 13 0 0 13 13 13 0 C2H2-type zinc-finger domain adh_short PF00106.25 KFM75403.1 - 1.3e-17 64.0 0.0 2.9e-09 36.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFM75403.1 - 1.9e-14 53.8 0.0 3.1e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DDE_3 PF13358.6 KFM75404.1 - 4.5e-16 58.9 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75404.1 - 7.8e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM75404.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM75404.1 - 0.0025 17.6 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75404.1 - 0.016 15.3 0.1 0.064 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM75404.1 - 0.034 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix IFNGR1 PF07140.11 KFM75405.1 - 0.025 14.7 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) zf-H2C2_2 PF13465.6 KFM75406.1 - 5.7e-12 45.5 11.7 5.2e-09 36.1 1.8 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75406.1 - 3.5e-09 36.6 14.0 9e-05 22.7 3.3 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75406.1 - 3.5e-08 33.6 12.8 0.00017 22.1 2.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-AN1 PF01428.16 KFM75406.1 - 4.2e-05 23.6 8.3 0.015 15.5 1.3 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger zf-trcl PF13451.6 KFM75406.1 - 0.00053 19.8 1.8 0.35 10.8 0.1 2.1 2 0 0 2 2 2 2 Probable zinc-ribbon domain CpXC PF14353.6 KFM75406.1 - 0.00068 19.7 1.6 0.5 10.4 0.2 2.0 1 1 1 2 2 2 2 CpXC protein zf-TRAF PF02176.18 KFM75406.1 - 0.0011 19.6 4.2 0.0016 19.1 4.2 1.4 1 1 0 1 1 1 1 TRAF-type zinc finger Zn-ribbon_8 PF09723.10 KFM75406.1 - 0.0028 17.7 2.0 1.3 9.2 0.1 2.2 2 0 0 2 2 2 2 Zinc ribbon domain zf-FCS PF06467.14 KFM75406.1 - 0.003 17.5 4.4 0.098 12.6 0.7 2.1 1 1 1 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-Sec23_Sec24 PF04810.15 KFM75406.1 - 0.008 16.2 1.5 0.16 12.0 0.3 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 KFM75406.1 - 0.0081 15.9 7.6 0.21 11.4 1.1 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-met PF12874.7 KFM75406.1 - 0.012 15.9 1.8 0.012 15.9 1.8 2.4 2 1 0 2 2 2 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.7 KFM75406.1 - 0.022 14.7 2.6 1.6 8.8 0.2 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PyrI_C PF02748.15 KFM75406.1 - 0.023 14.6 0.9 0.17 11.8 0.1 2.0 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DNA_RNApol_7kD PF03604.13 KFM75406.1 - 0.027 14.1 0.3 0.83 9.4 0.0 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 KFM75406.1 - 0.028 14.3 1.1 4.5 7.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.8 KFM75406.1 - 0.035 14.4 8.5 0.42 11.0 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM75406.1 - 0.051 13.9 8.8 0.74 10.2 1.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM75406.1 - 0.051 13.5 0.5 0.051 13.5 0.5 2.3 2 1 0 2 2 2 0 zinc-finger of a C2HC-type TF_Zn_Ribbon PF08271.12 KFM75406.1 - 0.052 13.1 1.0 0.17 11.4 1.0 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding Elf1 PF05129.13 KFM75406.1 - 0.099 12.7 3.6 0.32 11.1 3.6 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_3rep PF18868.1 KFM75406.1 - 0.12 13.1 6.6 2.6 8.7 3.2 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KFM75406.1 - 0.14 11.8 7.1 0.57 9.8 0.3 2.6 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Transp_Tc5_C PF04236.15 KFM75406.1 - 0.17 12.3 5.5 1.9 8.9 0.7 2.1 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain FYDLN_acid PF09538.10 KFM75406.1 - 0.17 12.6 0.1 1.1 10.0 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-C2HE PF16278.5 KFM75406.1 - 0.43 11.1 13.0 1.9 9.0 1.9 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger IBR PF01485.21 KFM75406.1 - 0.46 10.7 5.3 1.8 8.9 5.3 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE PF01363.21 KFM75406.1 - 0.7 10.1 6.4 1.6 8.9 6.4 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_7 PF15269.6 KFM75406.1 - 0.83 9.8 9.7 0.17 12.0 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger C5HCH PF17982.1 KFM75406.1 - 1.7 8.9 8.3 1.3 9.3 2.2 2.2 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-Di19 PF05605.12 KFM75406.1 - 2.3 8.6 9.0 1.8 8.9 1.5 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KFM75407.1 - 5.1e-11 42.5 4.0 2.5e-08 34.0 0.7 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM75407.1 - 5.6e-10 38.8 0.1 5.6e-10 38.8 0.1 2.2 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM75407.1 - 0.00011 22.7 6.8 0.14 13.0 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM75407.1 - 0.0058 17.0 13.4 0.018 15.5 1.7 2.9 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KFM75407.1 - 0.015 15.6 1.9 0.022 15.0 1.9 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KFM75407.1 - 0.038 13.8 3.1 0.06 13.2 1.4 1.9 1 1 1 2 2 2 0 GAGA factor DUF2719 PF10891.8 KFM75407.1 - 0.042 13.7 0.1 0.049 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) Zf_RING PF16744.5 KFM75407.1 - 0.057 13.5 3.9 0.22 11.6 0.5 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger C1_2 PF03107.16 KFM75407.1 - 0.076 13.3 3.4 4.1 7.8 0.3 2.3 2 0 0 2 2 2 0 C1 domain C1_4 PF07975.12 KFM75407.1 - 0.23 11.7 4.4 5.4 7.3 0.8 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 KFM75407.1 - 0.54 10.3 8.4 0.44 10.6 1.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Fer4_14 PF13394.6 KFM75409.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain AMP-binding PF00501.28 KFM75410.1 - 2e-72 244.1 0.0 2.6e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM75410.1 - 1.5e-23 83.6 0.5 3e-23 82.6 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Voltage_CLC PF00654.20 KFM75411.1 - 1.4e-71 241.6 18.5 1.7e-71 241.3 18.5 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KFM75411.1 - 2.8e-13 50.1 0.1 3e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 CBS domain TAT_signal PF10518.9 KFM75411.1 - 0.91 9.5 15.7 0.85 9.6 6.9 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence CUB PF00431.20 KFM75415.1 - 9.8e-25 87.0 0.0 1.3e-06 28.7 0.0 3.8 3 2 0 3 3 3 3 CUB domain CUB PF00431.20 KFM75416.1 - 1.7e-52 176.4 0.2 1.4e-12 47.9 0.0 4.4 4 0 0 4 4 4 4 CUB domain RVT_1 PF00078.27 KFM75418.1 - 2.1e-09 37.3 0.0 4.6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 KFM75419.1 - 3.2e-21 76.0 0.1 6.3e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF2671 PF10877.8 KFM75419.1 - 0.034 13.9 1.3 0.079 12.8 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) Ribosomal_L29 PF00831.23 KFM75420.1 - 6e-19 67.8 2.3 6e-19 67.8 2.3 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein RPN13_C PF16550.5 KFM75421.1 - 4.6e-32 110.5 4.4 4.6e-32 110.5 4.4 1.8 2 0 0 2 2 2 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KFM75421.1 - 2.3e-31 108.2 0.1 3.7e-31 107.5 0.1 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor ASXH PF13919.6 KFM75421.1 - 0.0016 18.4 0.1 0.099 12.7 0.0 2.5 2 0 0 2 2 2 1 Asx homology domain DDE_3 PF13358.6 KFM75422.1 - 6.3e-12 45.5 0.1 4.9e-05 23.1 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease zf-BED PF02892.15 KFM75423.1 - 6.9e-10 38.8 0.2 1.3e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 BED zinc finger DUF659 PF04937.15 KFM75423.1 - 4.6e-07 29.8 0.4 4.6e-07 29.8 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) ERAP1_C PF11838.8 KFM75424.1 - 4.3e-75 253.2 2.0 6.2e-75 252.7 2.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFM75424.1 - 4.9e-71 238.7 3.2 4.9e-71 238.7 3.2 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFM75424.1 - 3.6e-49 167.5 0.0 5.4e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3456 PF11938.8 KFM75426.1 - 4e-37 128.1 1.4 5.2e-37 127.8 1.4 1.1 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_1 PF05184.15 KFM75426.1 - 0.15 12.1 3.3 0.67 10.0 0.1 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 HATPase_c PF02518.26 KFM75427.1 - 0.0018 18.8 0.0 0.0025 18.3 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFM75427.1 - 0.041 13.7 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ANF_receptor PF01094.28 KFM75428.1 - 2e-09 37.0 0.0 2.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region GRASP55_65 PF04495.14 KFM75429.1 - 1.7e-74 248.7 0.0 3.1e-55 186.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KFM75429.1 - 2.1e-08 34.3 0.0 0.00017 21.8 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM75429.1 - 5.3e-07 29.4 0.0 0.042 13.7 0.0 2.7 2 1 0 2 2 2 2 PDZ domain HTH_Tnp_Tc3_2 PF01498.18 KFM75431.1 - 2.1e-16 59.9 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75431.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM75432.1 - 2.8e-16 59.6 0.1 2.9e-15 56.3 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75432.1 - 1.3e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase BHD_3 PF10405.9 KFM75438.1 - 4.6e-28 97.4 0.0 8.9e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KFM75438.1 - 6.4e-20 71.3 20.2 1.4e-18 67.0 20.2 2.8 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KFM75438.1 - 4.1e-18 65.0 0.0 8e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KFM75438.1 - 3.4e-10 40.7 1.7 3.4e-10 40.7 1.7 3.9 3 2 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KFM75438.1 - 0.0015 19.0 0.0 0.28 11.7 0.0 2.6 2 0 0 2 2 2 1 Transglutaminase-like superfamily HTH_Tnp_Tc3_2 PF01498.18 KFM75440.1 - 3.4e-16 59.3 4.0 4.5e-16 58.9 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75440.1 - 9.5e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75441.1 - 2.7e-14 53.2 1.0 4.9e-14 52.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75441.1 - 6.1e-14 52.0 0.0 7.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_1 PF00001.21 KFM75443.1 - 2.8e-34 118.7 0.9 3.9e-34 118.2 0.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM75443.1 - 3.9e-07 30.0 6.4 5.6e-07 29.4 6.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFM75443.1 - 2.7e-05 24.0 5.5 4.2e-05 23.4 5.5 1.3 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 KFM75443.1 - 0.00028 20.3 8.1 0.00049 19.5 8.1 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFM75443.1 - 0.00076 18.9 3.3 0.0013 18.2 3.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFM75443.1 - 1 8.7 12.8 5.6 6.2 12.8 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv HTH_Tnp_Tc3_2 PF01498.18 KFM75444.1 - 2.2e-16 59.9 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75444.1 - 1.6e-13 50.7 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Prot_ATP_OB_N PF17758.1 KFM75445.1 - 0.062 13.0 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM75446.1 - 5.9e-16 58.5 1.1 1.2e-15 57.4 1.1 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75446.1 - 0.00027 20.7 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75446.1 - 0.0053 16.5 0.8 0.0089 15.8 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM75446.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase SNF PF00209.18 KFM75447.1 - 3.5e-34 118.4 3.8 4e-34 118.2 3.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family MFS_1 PF07690.16 KFM75449.1 - 9.9e-07 28.0 3.7 1.2e-06 27.7 3.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily LRR_8 PF13855.6 KFM75450.1 - 2.9e-19 68.6 6.8 4e-08 32.9 0.3 4.6 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 KFM75450.1 - 5.7e-09 36.1 8.5 0.00041 20.7 0.1 4.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM75450.1 - 8.3e-08 32.3 4.0 8.1e-07 29.0 0.6 2.3 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM75450.1 - 0.00076 19.0 4.9 0.17 11.4 0.6 2.3 1 1 0 2 2 2 2 Leucine-rich repeat LRRCT PF01463.24 KFM75450.1 - 0.0039 17.6 0.0 0.015 15.8 0.0 2.0 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 KFM75450.1 - 0.01 16.2 4.9 13 6.8 1.0 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat AA_permease_2 PF13520.6 KFM75451.1 - 0.015 14.2 1.2 0.016 14.1 1.2 1.1 1 0 0 1 1 1 0 Amino acid permease DUF4022 PF13214.6 KFM75451.1 - 0.042 14.1 0.6 0.059 13.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) SLATT_5 PF18160.1 KFM75451.1 - 0.85 8.9 2.9 1 8.6 2.9 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 AA_permease_2 PF13520.6 KFM75452.1 - 2.1e-36 125.7 23.4 2.5e-36 125.4 23.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM75452.1 - 4.2e-30 104.8 20.4 5.1e-30 104.5 20.4 1.0 1 0 0 1 1 1 1 Amino acid permease Oxidored_q4 PF00507.19 KFM75452.1 - 1.8 8.8 5.9 2.5 8.3 4.7 2.0 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Reticulon PF02453.17 KFM75452.1 - 1.9 8.4 8.7 0.81 9.6 2.1 2.8 3 0 0 3 3 3 0 Reticulon TcpE PF12648.7 KFM75452.1 - 2.3 8.8 5.8 11 6.6 1.8 2.8 3 0 0 3 3 3 0 TcpE family YrhC PF14143.6 KFM75452.1 - 4.6 7.4 6.6 3.5 7.8 0.7 2.7 2 0 0 2 2 2 0 YrhC-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM75453.1 - 4.7e-22 78.0 2.5 1.5e-21 76.4 2.5 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75453.1 - 1.6e-13 50.7 0.1 4.5e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM75453.1 - 0.00012 22.6 6.7 0.00049 20.7 0.3 3.4 2 1 1 3 3 3 1 Homeodomain-like domain PAX PF00292.18 KFM75453.1 - 0.0018 18.2 0.9 0.0044 16.9 0.9 1.6 1 0 0 1 1 1 1 'Paired box' domain HTH_12 PF08461.10 KFM75453.1 - 0.0028 17.6 0.1 0.0072 16.2 0.1 1.7 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Sigma70_r4_2 PF08281.12 KFM75453.1 - 0.0046 16.6 0.2 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 KFM75453.1 - 0.012 15.4 0.3 0.16 11.8 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM75453.1 - 0.014 15.2 2.8 0.017 14.9 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_21 PF13276.6 KFM75453.1 - 0.065 13.4 0.3 0.18 12.0 0.3 1.8 1 0 0 1 1 1 0 HTH-like domain DUF2774 PF11242.8 KFM75453.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) zf-H2C2_2 PF13465.6 KFM75454.1 - 4.6e-43 143.8 53.2 1.5e-08 34.6 1.9 8.2 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75454.1 - 1.7e-39 132.0 79.2 1.2e-05 25.5 2.7 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75454.1 - 1.7e-22 78.1 69.4 0.0028 18.3 0.8 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM75454.1 - 4.3e-20 71.2 54.1 0.0018 18.2 1.1 8.3 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75454.1 - 5e-12 45.8 39.0 0.0024 18.1 0.5 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM75454.1 - 2.1e-11 43.8 60.0 0.00068 19.9 0.6 8.2 8 0 0 8 8 8 7 Zinc-finger of C2H2 type ADK_lid PF05191.14 KFM75454.1 - 0.0016 18.4 26.2 0.24 11.4 5.3 5.7 3 2 2 5 5 5 2 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM75454.1 - 0.024 14.7 25.5 2.6 8.2 0.1 7.5 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Chal_sti_synt_N PF00195.19 KFM75454.1 - 0.17 11.3 1.8 0.74 9.2 0.3 2.4 1 1 1 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain zf_ZIC PF18366.1 KFM75454.1 - 0.43 10.7 32.4 9.5 6.4 1.0 7.0 3 2 4 7 7 7 0 Zic proteins zinc finger domain GAGA PF09237.11 KFM75454.1 - 0.56 10.1 26.4 0.41 10.5 1.0 6.0 2 2 4 6 6 6 0 GAGA factor FYVE PF01363.21 KFM75454.1 - 0.58 10.3 44.3 0.074 13.2 9.1 4.6 1 1 3 4 4 4 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM75454.1 - 0.65 10.8 26.3 3.2 8.5 0.7 4.2 1 1 1 4 4 4 0 zinc-ribbon family FYVE_2 PF02318.16 KFM75454.1 - 2.1 8.6 29.5 2.8 8.2 4.7 4.2 1 1 2 4 4 4 0 FYVE-type zinc finger zf_UBZ PF18439.1 KFM75454.1 - 4.9 6.8 33.0 11 5.7 0.1 7.4 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger Vma12 PF11712.8 KFM75455.1 - 0.05 13.7 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Adeno_E3_CR2 PF02439.15 KFM75455.1 - 7.6 6.4 8.8 0.13 12.0 1.6 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 G-alpha PF00503.20 KFM75456.1 - 2.9e-77 260.2 6.7 3.3e-77 260.1 6.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFM75456.1 - 3.8e-14 52.5 0.7 7.6e-14 51.5 0.7 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM75456.1 - 4.8e-05 22.8 2.6 7.4e-05 22.2 2.6 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KFM75456.1 - 0.06 13.6 1.2 0.16 12.2 0.1 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DDE_3 PF13358.6 KFM75457.1 - 5.8e-16 58.6 0.1 6.3e-15 55.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75457.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Prefoldin_2 PF01920.20 KFM75458.1 - 2.1e-19 69.4 9.7 2.4e-19 69.3 9.7 1.0 1 0 0 1 1 1 1 Prefoldin subunit Ago_N_1 PF18351.1 KFM75458.1 - 0.012 16.0 0.7 0.091 13.2 0.1 2.0 2 0 0 2 2 2 0 Fungal Argonaute N-terminal domain DUF4200 PF13863.6 KFM75458.1 - 0.016 15.6 0.9 0.016 15.6 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF5082 PF16888.5 KFM75458.1 - 0.052 13.8 5.5 0.076 13.3 5.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) SPATA24 PF15175.6 KFM75458.1 - 0.06 13.2 9.6 0.64 9.9 0.5 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 Lectin_N PF03954.14 KFM75458.1 - 0.079 12.7 2.7 0.11 12.2 0.4 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Spc24 PF08286.11 KFM75458.1 - 0.76 10.0 7.9 3.7 7.8 0.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 JLPA PF16668.5 KFM75460.1 - 0.0085 15.2 0.1 0.01 14.9 0.1 1.1 1 0 0 1 1 1 1 Adhesin from Campylobacter DUF2048 PF09752.9 KFM75460.1 - 0.1 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 PDZ_assoc PF10600.9 KFM75460.1 - 0.39 11.6 2.3 13 6.7 0.1 2.6 2 1 0 2 2 2 0 PDZ-associated domain of NMDA receptors Neurokinin_B PF03823.14 KFM75463.1 - 0.15 12.1 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Neurokinin B PQQ_2 PF13360.6 KFM75466.1 - 2e-05 24.3 0.0 0.0001 21.9 0.0 1.9 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 KFM75466.1 - 0.00011 21.9 0.9 0.0028 17.5 0.0 3.3 3 1 1 4 4 4 1 PQQ enzyme repeat ubiquitin PF00240.23 KFM75467.1 - 9e-19 67.0 1.6 1.5e-18 66.3 1.6 1.4 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 KFM75467.1 - 1.6e-08 34.3 41.7 0.00016 21.5 5.6 6.4 4 2 2 6 6 6 4 STI1 domain Rad60-SLD PF11976.8 KFM75467.1 - 2e-06 27.5 2.1 4.5e-06 26.4 2.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 KFM75467.1 - 3.9e-05 23.5 0.1 0.00012 21.9 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_5 PF18037.1 KFM75467.1 - 0.00031 21.0 3.5 0.0006 20.1 3.5 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 KFM75467.1 - 0.00052 20.5 0.2 0.0029 18.1 0.1 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFM75467.1 - 0.00077 19.5 0.4 0.0019 18.3 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KFM75467.1 - 0.0062 16.6 3.1 0.36 10.9 3.1 2.5 1 1 0 1 1 1 1 Ubiquitin-like domain UN_NPL4 PF11543.8 KFM75467.1 - 0.012 16.1 0.2 0.024 15.1 0.2 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mod_r PF07200.13 KFM75467.1 - 0.028 14.5 5.9 1.6 8.8 0.0 4.4 3 2 2 5 5 5 0 Modifier of rudimentary (Mod(r)) protein HOIP-UBA PF16678.5 KFM75467.1 - 0.069 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 HOIP UBA domain pair Mucin PF01456.17 KFM75467.1 - 0.95 9.4 23.9 0.14 12.2 19.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein ComX PF05952.12 KFM75467.1 - 0.96 9.4 6.6 34 4.5 0.4 5.1 6 0 0 6 6 6 0 Bacillus competence pheromone ComX HTH_Tnp_Tc3_2 PF01498.18 KFM75468.1 - 1.8e-16 60.1 2.2 4e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75468.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Katanin_con80 PF13925.6 KFM75469.1 - 4.5e-37 127.6 0.6 4.8e-37 127.5 0.6 1.0 1 0 0 1 1 1 1 con80 domain of Katanin VWD PF00094.25 KFM75470.1 - 1.5e-37 129.3 3.0 2.4e-37 128.7 3.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 KFM75470.1 - 7e-15 55.2 6.7 7e-15 55.2 6.7 3.0 3 1 0 3 3 3 1 C8 domain TIL PF01826.17 KFM75470.1 - 5.7e-13 48.9 18.4 5.7e-13 48.9 18.4 3.8 4 0 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFM75470.1 - 9.5e-09 35.4 13.5 9.5e-09 35.4 13.5 4.0 2 1 0 2 2 2 1 von Willebrand factor type C domain DUF525 PF04379.14 KFM75472.1 - 2e-26 92.1 0.1 3.2e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.11 KFM75472.1 - 3.6e-07 30.6 0.1 8.5e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like TPR_8 PF13181.6 KFM75475.1 - 0.31 11.3 2.5 0.97 9.8 1.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 KFM75478.1 - 0.0025 18.6 0.1 0.0076 17.1 0.3 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Memo PF01875.17 KFM75480.1 - 2.1e-46 158.3 0.1 2.3e-46 158.1 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM75481.1 - 1.2e-09 38.3 4.9 2.2e-05 24.6 1.3 2.6 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM75481.1 - 1.5e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM75481.1 - 5.2 7.7 9.8 0.6 10.8 0.1 2.9 3 0 0 3 3 3 0 Homeodomain-like domain Neur_chan_memb PF02932.16 KFM75482.1 - 0.073 13.1 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SARAF PF06682.12 KFM75482.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Amnionless PF14828.6 KFM75483.1 - 0.052 12.4 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless Ank_4 PF13637.6 KFM75484.1 - 3.2e-17 62.7 0.1 1.7e-12 47.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM75484.1 - 5.9e-16 58.8 0.5 2e-15 57.1 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM75484.1 - 5.4e-14 50.9 0.1 9.4e-06 25.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KFM75484.1 - 9.5e-14 51.1 0.0 4.4e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFM75484.1 - 8.2e-13 48.3 0.3 1.4e-08 34.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 KFM75484.1 - 2.6e-11 42.9 0.8 2.6e-11 42.9 0.8 2.6 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 KFM75484.1 - 3.4e-09 36.4 0.5 7.8e-09 35.3 0.5 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM75484.1 - 3.7e-06 26.5 0.1 1.2e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain DUF5614 PF18474.1 KFM75484.1 - 2.2 7.5 7.0 0.79 9.0 2.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5614) NUDIX PF00293.28 KFM75485.1 - 0.0039 17.2 0.0 0.0076 16.3 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain DUF4364 PF14277.6 KFM75485.1 - 0.024 14.4 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) 7tm_1 PF00001.21 KFM75486.1 - 1.1e-14 54.4 3.1 1.1e-14 54.4 3.1 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM75486.1 - 0.00031 20.2 2.4 0.00031 20.2 2.4 1.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFM75486.1 - 0.0015 18.3 4.1 0.0018 18.1 4.1 1.1 1 0 0 1 1 1 1 Olfactory receptor Benyvirus_P25 PF05744.11 KFM75486.1 - 0.085 12.1 0.5 0.17 11.2 0.5 1.5 1 0 0 1 1 1 0 Benyvirus P25/P26 protein Cystatin PF00031.21 KFM75487.1 - 1.1e-16 60.9 1.2 1.3e-16 60.6 1.2 1.1 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFM75487.1 - 0.0021 18.4 0.2 0.004 17.5 0.2 1.4 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor DUF4973 PF16343.5 KFM75487.1 - 0.091 12.8 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4973) RT_RNaseH_2 PF17919.1 KFM75488.1 - 4.3e-31 106.9 0.0 1.2e-30 105.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM75488.1 - 2.2e-28 99.3 1.4 5e-28 98.1 0.2 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KFM75488.1 - 3.7e-28 97.9 0.0 1.1e-27 96.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KFM75488.1 - 2.1e-19 69.4 0.2 2.1e-19 69.4 0.2 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 KFM75488.1 - 3.2e-18 66.0 0.0 1.2e-15 57.8 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFM75488.1 - 3.4e-05 24.0 1.0 9.2e-05 22.6 1.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 KFM75488.1 - 0.0015 18.3 0.1 0.0084 15.9 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like BH4 PF02180.17 KFM75488.1 - 0.044 13.6 0.1 0.098 12.5 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 BEN PF10523.9 KFM75488.1 - 0.15 12.3 1.2 2.7 8.3 0.0 3.3 3 0 0 3 3 3 0 BEN domain DHR10 PF18595.1 KFM75488.1 - 7.4 6.7 15.9 2.2 8.4 0.1 3.7 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Cystatin PF00031.21 KFM75489.1 - 2.7e-15 56.4 1.3 3.1e-15 56.2 1.3 1.1 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFM75489.1 - 0.013 15.8 0.3 0.018 15.4 0.3 1.2 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor HTH_32 PF13565.6 KFM75490.1 - 0.0085 16.7 1.9 0.025 15.2 0.8 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM75491.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75491.1 - 8.4e-14 51.5 0.0 1.4e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC_4 PF14392.6 KFM75492.1 - 0.011 15.4 8.3 0.33 10.7 2.0 2.7 2 0 0 2 2 2 0 Zinc knuckle HTH_Tnp_Tc3_2 PF01498.18 KFM75493.1 - 2.4e-16 59.7 2.2 4.3e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75493.1 - 6.3e-13 48.7 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease 2OG-FeII_Oxy_2 PF13532.6 KFM75495.1 - 4.7e-06 26.9 0.0 4.8e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DDE_Tnp_1_7 PF13843.6 KFM75498.1 - 6.5e-10 38.8 0.0 7.2e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 MNR PF15718.5 KFM75499.1 - 4e-06 25.3 0.1 4.9e-06 25.0 0.1 1.3 1 1 0 1 1 1 1 Protein moonraker HJURP_mid PF12346.8 KFM75499.1 - 0.04 14.4 0.1 0.055 13.9 0.1 1.3 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat Sulfotransfer_1 PF00685.27 KFM75501.1 - 0.019 14.5 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain RNA_pol_L_2 PF13656.6 KFM75502.1 - 3.7e-27 93.9 0.0 4.8e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFM75502.1 - 3.5e-09 36.0 0.0 5.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SHNi-TPR PF10516.9 KFM75502.1 - 0.034 13.6 0.1 0.12 11.8 0.0 1.8 1 1 1 2 2 2 0 SHNi-TPR PAP_central PF04928.17 KFM75504.1 - 3.2e-29 101.7 0.1 4e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFM75504.1 - 5.4e-19 68.5 0.1 6.8e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain zf-H2C2_2 PF13465.6 KFM75505.1 - 1.1e-67 221.6 67.4 3.9e-09 36.5 0.7 10.0 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75505.1 - 1e-47 158.0 71.1 4.8e-07 29.9 1.9 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75505.1 - 3e-32 108.5 71.2 8.3e-05 23.1 1.7 9.6 10 0 0 10 10 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM75505.1 - 1.7e-28 98.1 64.1 0.00032 21.0 3.7 9.5 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM75505.1 - 4.3e-20 71.2 63.5 0.00029 20.8 2.3 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75505.1 - 5.9e-18 64.7 55.1 0.043 14.1 0.5 9.4 8 1 1 9 9 9 9 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM75505.1 - 2.4e-10 40.3 34.1 0.055 13.5 0.1 8.9 4 2 5 9 9 9 4 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM75505.1 - 6.6e-08 32.3 35.4 0.29 11.0 0.6 8.9 2 2 7 9 9 9 3 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFM75505.1 - 2.7e-07 30.9 55.8 0.4 11.0 2.7 8.9 1 1 7 8 8 8 4 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM75505.1 - 3.1e-06 26.9 42.0 1.2 9.1 0.1 9.3 9 0 0 9 9 9 4 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM75505.1 - 4.2e-06 26.6 36.0 0.059 13.4 1.3 6.3 4 2 0 4 4 4 1 Adenylate kinase, active site lid BolA PF01722.18 KFM75505.1 - 1.7e-05 25.0 19.0 0.0076 16.5 0.3 5.9 1 1 6 7 7 7 2 BolA-like protein DUF2256 PF10013.9 KFM75505.1 - 0.00028 20.9 32.6 15 5.8 0.2 9.2 10 0 0 10 10 9 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 KFM75505.1 - 0.00067 19.4 20.1 0.37 10.6 0.7 6.8 2 2 6 8 8 8 3 GAGA factor zf-DBF PF07535.12 KFM75505.1 - 0.0014 18.7 40.3 3.2 7.9 0.0 9.2 8 1 1 9 9 9 2 DBF zinc finger zf_UBZ PF18439.1 KFM75505.1 - 0.0032 17.0 37.3 7.5 6.2 0.4 9.1 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM75505.1 - 0.011 15.4 43.2 1.3 8.6 0.2 8.9 3 3 6 9 9 9 0 MYST family zinc finger domain DUF4712 PF15830.5 KFM75505.1 - 0.02 14.6 0.7 0.051 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4712) zinc_ribbon_15 PF17032.5 KFM75505.1 - 0.028 15.2 36.0 0.35 11.7 3.8 4.9 1 1 4 6 6 6 0 zinc-ribbon family Complex1_49kDa PF00346.19 KFM75505.1 - 0.033 13.3 1.3 1.4 8.0 0.1 2.4 2 1 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-RRPl_C4 PF17026.5 KFM75505.1 - 0.047 13.8 37.1 2.1 8.5 6.6 4.2 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-BED PF02892.15 KFM75505.1 - 0.048 13.7 61.7 0.87 9.7 3.0 9.0 2 2 7 9 9 9 0 BED zinc finger Zn-ribbon_8 PF09723.10 KFM75505.1 - 0.088 12.9 33.0 0.22 11.7 1.4 6.4 2 2 5 7 7 7 0 Zinc ribbon domain YtxC PF08812.11 KFM75505.1 - 0.11 12.1 4.3 0.79 9.3 0.1 3.0 2 1 1 3 3 3 0 YtxC-like family zf-CHCC PF10276.9 KFM75505.1 - 0.17 11.9 19.2 41 4.3 0.1 7.6 9 0 0 9 9 8 0 Zinc-finger domain HNH_5 PF14279.6 KFM75505.1 - 0.43 10.5 40.8 3.1 7.7 0.4 8.1 4 3 1 6 6 6 0 HNH endonuclease PqqA PF08042.11 KFM75505.1 - 0.49 10.5 2.9 84 3.4 0.0 4.5 5 0 0 5 5 5 0 PqqA family TRAF6_Z2 PF18048.1 KFM75505.1 - 1.3 9.2 32.1 3.8 7.7 0.3 8.0 9 0 0 9 9 9 0 TNF receptor-associated factor 6 zinc finger 2 FYVE PF01363.21 KFM75505.1 - 2 8.6 47.3 12 6.2 5.0 5.7 1 1 3 5 5 5 0 FYVE zinc finger zf-FPG_IleRS PF06827.14 KFM75505.1 - 8 6.4 28.3 21 5.1 0.1 8.3 9 0 0 9 9 9 0 Zinc finger found in FPG and IleRS zf-H2C2_2 PF13465.6 KFM75506.1 - 9.2e-66 215.5 67.7 3.4e-09 36.7 1.1 10.2 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75506.1 - 5.1e-40 133.7 88.8 4.7e-07 29.9 2.0 9.2 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75506.1 - 6.3e-32 107.5 81.5 0.00028 21.5 1.4 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM75506.1 - 2.2e-16 59.6 78.1 0.00015 22.1 1.6 9.4 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM75506.1 - 6.4e-14 51.6 69.6 0.0012 18.8 2.0 9.5 9 1 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM75506.1 - 1.3e-12 47.3 55.8 0.0096 15.7 0.3 9.5 9 0 0 9 9 9 6 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM75506.1 - 2.3e-10 40.5 55.5 0.021 15.1 0.5 9.7 9 1 0 9 9 9 6 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM75506.1 - 2.1e-07 30.6 30.8 0.037 13.8 0.2 6.9 2 2 5 7 7 7 5 GAGA factor zf-C2HC_2 PF13913.6 KFM75506.1 - 0.00022 21.0 36.0 1.2 9.1 0.1 8.1 8 0 0 8 8 8 5 zinc-finger of a C2HC-type Tox-HNH-HHH PF15637.6 KFM75506.1 - 0.00051 20.2 3.2 8.5 6.6 0.2 4.7 1 1 4 6 6 6 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif ADK_lid PF05191.14 KFM75506.1 - 0.0024 17.8 35.5 0.0033 17.4 2.6 5.9 4 1 4 8 8 8 4 Adenylate kinase, active site lid zf-C2H2_9 PF16293.5 KFM75506.1 - 0.034 14.0 42.8 1.5 8.7 0.3 8.6 3 3 6 9 9 9 0 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM75506.1 - 0.047 13.7 33.4 1.8 8.7 0.5 7.7 6 2 1 7 7 7 0 Sec23/Sec24 zinc finger Zf_RING PF16744.5 KFM75506.1 - 0.19 11.9 50.8 1.5 9.0 3.1 8.2 2 2 5 7 7 7 0 KIAA1045 RING finger C1_1 PF00130.22 KFM75506.1 - 0.47 10.4 55.2 0.68 9.9 7.7 7.1 2 2 3 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.7 KFM75506.1 - 0.6 10.5 71.0 0.4 11.1 1.4 8.8 1 1 6 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM75506.1 - 5.3 7.2 38.6 2.2 8.4 5.4 4.5 1 1 2 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type RNase_H PF00075.24 KFM75507.1 - 1.9e-06 28.1 0.4 2.7e-06 27.6 0.3 1.5 1 1 0 1 1 1 1 RNase H zf-H2C2_2 PF13465.6 KFM75508.1 - 1.5e-92 300.2 81.0 8.2e-09 35.5 0.7 13.8 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75508.1 - 8.5e-68 221.2 116.2 2.6e-06 27.6 0.3 13.1 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75508.1 - 1.3e-47 156.3 108.9 0.00022 21.8 0.8 13.1 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM75508.1 - 4.5e-42 141.3 110.3 7.1e-06 26.2 3.5 13.2 13 0 0 13 13 13 13 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM75508.1 - 2.1e-31 107.3 89.7 0.00034 20.5 1.0 13.4 13 0 0 13 13 13 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75508.1 - 4.9e-26 90.4 80.3 0.00016 21.8 2.0 13.2 13 0 0 13 13 13 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM75508.1 - 3e-13 49.3 82.7 0.15 11.9 0.2 13.7 14 0 0 14 14 13 8 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM75508.1 - 1.6e-11 43.8 58.6 0.47 10.4 0.1 12.7 13 0 0 13 13 12 5 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM75508.1 - 1.2e-09 37.6 61.7 0.024 14.2 0.7 12.6 7 4 6 13 13 13 5 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 KFM75508.1 - 1.3e-09 37.9 56.4 0.34 11.0 0.5 12.7 7 3 6 13 13 13 4 Sec23/Sec24 zinc finger BolA PF01722.18 KFM75508.1 - 4.4e-08 33.3 25.8 0.0085 16.3 1.1 7.4 1 1 5 7 7 7 1 BolA-like protein zf-C2H2_2 PF12756.7 KFM75508.1 - 4.1e-06 27.1 90.7 0.44 10.9 1.8 12.8 1 1 11 12 12 12 4 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM75508.1 - 0.0001 22.2 53.7 0.073 13.1 2.1 8.7 3 3 6 10 10 10 5 Adenylate kinase, active site lid DUF952 PF06108.12 KFM75508.1 - 0.00027 20.9 3.0 11 6.1 0.0 5.7 2 1 4 7 7 7 0 Protein of unknown function (DUF952) DUF2256 PF10013.9 KFM75508.1 - 0.00094 19.3 48.0 10 6.3 0.1 12.5 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) Tox-HNH-HHH PF15637.6 KFM75508.1 - 0.0013 18.9 6.9 7.3 6.8 0.1 5.1 4 2 3 7 7 7 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zinc_ribbon_15 PF17032.5 KFM75508.1 - 0.0044 17.7 55.0 1.3 9.8 1.3 6.8 2 1 5 7 7 7 2 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM75508.1 - 0.0068 16.2 64.2 1.9 8.4 0.2 12.1 5 3 8 13 13 13 1 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 KFM75508.1 - 0.02 15.0 65.1 2.3 8.4 3.7 12.1 1 1 8 10 10 10 0 KIAA1045 RING finger zf-DBF PF07535.12 KFM75508.1 - 0.034 14.3 54.4 3.5 7.8 0.5 11.6 12 0 0 12 12 12 0 DBF zinc finger Closter_coat PF01785.17 KFM75508.1 - 0.046 13.0 0.3 0.046 13.0 0.3 2.9 4 0 0 4 4 4 0 Closterovirus coat protein zf_UBZ PF18439.1 KFM75508.1 - 0.077 12.6 63.4 2.8 7.6 1.1 12.6 13 0 0 13 13 13 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM75508.1 - 0.088 12.9 47.0 0.86 9.8 1.0 8.6 2 2 9 11 11 11 0 Zinc ribbon domain Yop-YscD_ppl PF16693.5 KFM75508.1 - 0.11 11.9 0.0 0.35 10.3 0.0 1.9 2 0 0 2 2 2 0 Inner membrane component of T3SS, periplasmic domain zf-RRPl_C4 PF17026.5 KFM75508.1 - 0.79 9.8 56.9 0.4 10.8 5.0 5.7 1 1 7 8 8 8 0 Putative ribonucleoprotein zinc-finger pf C4 type PqqA PF08042.11 KFM75508.1 - 1 9.5 3.0 71 3.6 0.0 4.7 6 0 0 6 6 6 0 PqqA family Prok-RING_1 PF14446.6 KFM75508.1 - 3.2 7.8 56.4 12 6.0 3.7 12.2 11 2 0 11 11 11 0 Prokaryotic RING finger family 1 zf-BED PF02892.15 KFM75508.1 - 4.1 7.5 93.4 0.85 9.7 2.6 12.5 1 1 12 13 13 13 0 BED zinc finger GAGA PF09237.11 KFM75508.1 - 5.7 6.8 35.8 5.9 6.8 0.2 8.0 2 2 8 10 10 10 0 GAGA factor Kunitz_BPTI PF00014.23 KFM75509.1 - 2.8e-51 171.5 58.3 1.9e-19 69.6 7.4 4.5 5 0 0 5 5 5 3 Kunitz/Bovine pancreatic trypsin inhibitor domain TIL PF01826.17 KFM75509.1 - 1.8e-25 88.9 44.0 3.4e-14 52.8 18.1 5.4 4 1 1 5 5 5 2 Trypsin Inhibitor like cysteine rich domain GBP_PSP PF02425.15 KFM75509.1 - 0.00056 19.5 5.5 0.32 10.7 0.4 3.5 2 0 0 2 2 2 2 Paralytic/GBP/PSP peptide DUF2724 PF10893.8 KFM75509.1 - 0.024 14.5 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2724) Kelch_4 PF13418.6 KFM75509.1 - 0.046 13.7 1.9 16 5.6 0.1 3.8 3 1 1 4 4 4 0 Galactose oxidase, central domain cEGF PF12662.7 KFM75509.1 - 0.062 13.2 8.2 2.1 8.3 0.2 3.7 3 0 0 3 3 3 0 Complement Clr-like EGF-like WW PF00397.26 KFM75509.1 - 0.13 12.4 0.7 50 4.1 0.1 3.3 3 0 0 3 3 3 0 WW domain Kelch_3 PF13415.6 KFM75509.1 - 0.14 12.5 3.7 4.9 7.6 0.1 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Kunitz_BPTI PF00014.23 KFM75510.1 - 3.2e-53 177.8 62.1 2.7e-19 69.1 8.4 4.5 5 0 0 5 5 5 3 Kunitz/Bovine pancreatic trypsin inhibitor domain TIL PF01826.17 KFM75510.1 - 4.1e-25 87.8 44.0 6.4e-14 51.9 18.1 5.8 5 2 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain WW PF00397.26 KFM75510.1 - 0.039 14.1 2.2 27 5.0 0.1 3.4 3 0 0 3 3 3 0 WW domain DUF2724 PF10893.8 KFM75510.1 - 0.082 12.8 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2724) Kelch_3 PF13415.6 KFM75510.1 - 0.12 12.7 4.0 26 5.2 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain GBP_PSP PF02425.15 KFM75510.1 - 0.17 11.5 0.3 0.17 11.5 0.3 4.0 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Sulfotransfer_1 PF00685.27 KFM75512.1 - 4.1e-36 124.8 0.4 1.6e-35 122.9 0.4 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM75512.1 - 4.1e-07 30.6 0.0 7.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family DDE_3 PF13358.6 KFM75513.1 - 0.0031 17.3 0.0 0.0037 17.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TALPID3 PF15324.6 KFM75514.1 - 0.027 12.2 1.0 0.035 11.8 1.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target WASH-7_mid PF14744.6 KFM75514.1 - 0.72 8.9 4.1 0.12 11.4 0.6 1.4 2 0 0 2 2 2 0 WASH complex subunit 7 CsgA PF17334.2 KFM75514.1 - 0.8 10.5 3.0 6.7 7.5 1.0 2.9 2 1 1 3 3 3 0 Minor curli fiber component A MT-A70 PF05063.14 KFM75515.1 - 2e-41 141.8 0.3 2.9e-41 141.2 0.3 1.3 1 0 0 1 1 1 1 MT-A70 Helicase_C PF00271.31 KFM75516.1 - 9.7e-10 38.8 0.0 4.5e-09 36.6 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM75516.1 - 2.7e-07 30.5 0.0 5.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFM75516.1 - 5.9e-05 23.4 0.0 0.0002 21.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM75516.1 - 7.7e-05 22.5 0.0 0.0002 21.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFM75516.1 - 0.00097 18.3 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KFM75516.1 - 0.0013 19.0 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KFM75516.1 - 0.0019 17.8 0.2 0.017 14.7 0.0 2.5 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KFM75516.1 - 0.01 15.8 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 KFM75516.1 - 0.065 12.7 0.0 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 KFM75516.1 - 0.62 9.8 0.0 0.62 9.8 0.0 3.9 3 1 1 4 4 2 0 AAA domain ResIII PF04851.15 KFM75516.1 - 2.7 8.0 10.2 2.1 8.3 0.0 3.5 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KFM75516.1 - 7.4 7.1 0.0 7.4 7.1 0.0 3.2 2 1 0 2 2 1 0 ABC transporter OB_NTP_bind PF07717.16 KFM75517.1 - 4.7e-13 49.3 0.0 6.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold zf-CCHC_4 PF14392.6 KFM75518.1 - 0.0048 16.6 8.3 0.54 10.0 1.7 2.7 2 0 0 2 2 2 2 Zinc knuckle DDE_Tnp_4 PF13359.6 KFM75519.1 - 4.1e-10 39.6 0.1 2.1e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM75519.1 - 3.4e-05 23.5 0.0 5.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein zf-CCHC_4 PF14392.6 KFM75520.1 - 0.013 15.2 9.9 0.83 9.4 3.5 2.5 2 0 0 2 2 2 0 Zinc knuckle SAM_PNT PF02198.16 KFM75521.1 - 1.9e-10 40.6 0.2 3.1e-10 39.9 0.2 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain His_Phos_1 PF00300.22 KFM75522.1 - 4.8e-39 134.1 1.6 1.8e-35 122.4 0.4 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Sulfotransfer_1 PF00685.27 KFM75523.1 - 2.4e-68 230.5 2.4 3.7e-68 229.9 2.4 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM75523.1 - 2.2e-10 41.3 0.1 6.4e-06 26.7 0.1 2.4 2 0 0 2 2 2 2 Sulfotransferase family MarR_2 PF12802.7 KFM75524.1 - 9.7e-05 22.2 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 MarR family PAX PF00292.18 KFM75524.1 - 0.00014 21.8 0.0 0.00014 21.8 0.0 1.0 1 0 0 1 1 1 1 'Paired box' domain HTH_29 PF13551.6 KFM75524.1 - 0.0014 18.6 0.1 0.0016 18.4 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KFM75524.1 - 0.0017 18.1 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 KFM75524.1 - 0.0017 18.4 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM75524.1 - 0.018 15.2 0.1 0.023 14.8 0.1 1.3 1 1 0 1 1 1 0 Helix-turn-helix domain DUF433 PF04255.14 KFM75524.1 - 0.16 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Glypican PF01153.19 KFM75525.1 - 3.1e-132 442.3 0.0 4.1e-132 441.8 0.0 1.0 1 0 0 1 1 1 1 Glypican Asp_Arg_Hydrox PF05118.15 KFM75528.1 - 5.4e-57 192.0 0.0 7.8e-57 191.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_2 PF07719.17 KFM75528.1 - 1.4e-09 37.3 5.2 0.01 15.9 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM75528.1 - 8.4e-09 35.0 3.3 0.0061 16.7 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM75528.1 - 7.1e-08 32.6 0.2 1.4 10.0 0.1 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM75528.1 - 1.1e-07 32.3 0.1 0.0018 18.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM75528.1 - 8.6e-06 26.3 0.3 0.00064 20.3 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM75528.1 - 9.9e-06 25.9 0.5 3.6 8.4 0.2 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM75528.1 - 3.1e-05 24.2 1.7 0.014 15.7 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM75528.1 - 0.00016 21.4 2.4 0.62 10.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM75528.1 - 0.00028 20.7 1.5 1.1 9.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM75528.1 - 0.00069 19.3 6.3 0.14 11.8 0.0 3.6 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.28 KFM75528.1 - 0.0022 17.7 6.8 0.99 9.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 KFM75528.1 - 0.0037 17.7 0.1 0.037 14.5 0.0 2.3 2 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 KFM75528.1 - 0.0099 16.2 0.0 0.1 12.9 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 KFM75528.1 - 0.031 14.0 0.3 0.093 12.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_5 PF12688.7 KFM75528.1 - 0.17 12.1 0.1 2.3 8.5 0.0 2.4 1 1 0 2 2 2 0 Tetratrico peptide repeat AAA PF00004.29 KFM75529.1 - 2.2e-37 128.5 0.0 4.6e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM75529.1 - 1.2e-08 34.6 0.0 4.1e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KFM75529.1 - 1.3e-07 31.5 0.1 5.9e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KFM75529.1 - 1.1e-05 25.2 0.0 2.7e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM75529.1 - 0.00088 19.7 1.9 0.15 12.4 0.1 3.0 1 1 2 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFM75529.1 - 0.00091 19.2 0.3 0.0095 15.9 0.3 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM75529.1 - 0.0019 18.4 2.3 0.24 11.7 0.2 3.5 1 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 KFM75529.1 - 0.002 17.4 0.0 0.0039 16.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KFM75529.1 - 0.0062 17.1 0.0 0.022 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KFM75529.1 - 0.024 14.4 0.1 2.2 8.0 0.1 2.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 KFM75529.1 - 0.028 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KFM75529.1 - 0.065 13.0 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFM75529.1 - 0.071 12.5 0.1 0.19 11.1 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KFM75529.1 - 0.14 11.4 0.6 2.1 7.6 0.6 2.5 1 1 0 1 1 1 0 KaiC ACOX PF01756.19 KFM75530.1 - 7.5e-54 182.0 2.2 1.6e-53 181.0 2.2 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KFM75530.1 - 2.7e-35 121.6 0.1 5.7e-35 120.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFM75530.1 - 1.9e-08 34.4 0.0 4.1e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFM75530.1 - 0.00073 19.8 0.5 0.003 17.8 0.5 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM75530.1 - 0.13 12.9 0.0 0.41 11.3 0.0 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain EF-hand_7 PF13499.6 KFM75531.1 - 4.5e-08 33.4 4.6 0.00028 21.3 0.8 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM75531.1 - 1.1e-07 31.2 1.5 0.0062 16.4 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KFM75531.1 - 1.2e-06 27.6 3.7 0.0079 15.7 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KFM75531.1 - 9.6e-05 22.2 2.0 0.65 9.9 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair Calpain_III PF01067.22 KFM75531.1 - 0.029 14.7 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Calpain large subunit, domain III EF-hand_5 PF13202.6 KFM75531.1 - 0.22 11.1 0.9 2.4 7.8 0.4 2.9 3 0 0 3 3 3 0 EF hand ParBc PF02195.18 KFM75532.1 - 1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 ParB-like nuclease domain RVT_1 PF00078.27 KFM75534.1 - 0.039 13.5 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 KFM75535.1 - 2.5e-07 30.4 0.0 6e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KFM75535.1 - 3.3e-07 30.3 1.2 0.0048 16.8 0.7 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Propep_M14 PF02244.16 KFM75535.1 - 1.7 9.1 4.7 4 7.9 0.7 3.1 4 0 0 4 4 4 0 Carboxypeptidase activation peptide DDE_3 PF13358.6 KFM75536.1 - 1.7e-14 53.8 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75537.1 - 1.8e-19 69.8 3.8 4.3e-19 68.5 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75537.1 - 3.7e-16 59.2 0.0 2e-15 56.8 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM75537.1 - 2.2e-07 30.8 0.9 0.00011 22.2 0.0 2.7 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM75537.1 - 2.7e-07 31.1 2.0 2.7e-07 31.1 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75537.1 - 1e-06 28.7 3.1 6e-05 23.1 0.2 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75537.1 - 1.3e-06 28.0 3.6 2e-05 24.2 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM75537.1 - 1.9e-06 27.8 0.7 3.1e-05 23.9 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM75537.1 - 0.00011 22.0 0.7 0.0013 18.5 0.0 2.3 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM75537.1 - 0.00083 19.3 0.4 0.013 15.5 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 KFM75537.1 - 0.016 14.9 0.1 0.086 12.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM75537.1 - 0.041 14.0 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM75537.1 - 0.059 13.6 0.1 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KFM75537.1 - 0.11 12.0 0.2 0.66 9.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_22 PF13309.6 KFM75537.1 - 0.12 12.5 0.0 24 5.1 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KFM75537.1 - 0.17 11.7 3.8 1.2 9.0 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain TrmB PF01978.19 KFM75537.1 - 0.17 11.8 0.0 6.1 6.8 0.0 2.3 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Tnp_ISL3 PF13542.6 KFM75537.1 - 0.76 9.2 3.6 5.8 6.4 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc3_2 PF01498.18 KFM75538.1 - 1.9e-16 60.1 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75538.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75539.1 - 2.1e-16 59.9 2.2 4e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75539.1 - 7e-14 51.8 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.32 KFM75540.1 - 3.9e-20 71.8 8.4 1.8e-05 25.4 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM75540.1 - 6.8e-06 26.3 0.0 4.7 7.6 0.0 4.3 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM75540.1 - 0.00087 19.2 0.1 1.6 8.6 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFM75540.1 - 0.039 12.6 1.2 0.4 9.3 0.2 2.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Hira PF07569.11 KFM75540.1 - 0.061 13.0 0.2 13 5.4 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KFM75540.1 - 0.076 12.0 0.5 0.64 8.9 0.0 2.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFM75540.1 - 0.1 12.5 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KFM75540.1 - 0.11 13.0 0.3 3.4 8.3 0.0 3.4 5 0 0 5 5 5 0 PQQ-like domain Neur_chan_LBD PF02931.23 KFM75541.1 - 1.2e-23 83.7 1.3 1.3e-23 83.6 1.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DDE_Tnp_1_7 PF13843.6 KFM75542.1 - 2.9e-49 168.2 0.4 3.9e-49 167.8 0.4 1.1 1 0 0 1 1 1 1 Transposase IS4 MitMem_reg PF13012.6 KFM75542.1 - 0.14 12.5 0.1 0.25 11.8 0.1 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function ABC_tran PF00005.27 KFM75544.1 - 1.6e-10 41.7 0.0 2.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM75544.1 - 1.2e-05 25.2 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFM75544.1 - 0.00071 20.1 0.0 0.00094 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFM75544.1 - 0.0024 17.4 0.0 0.061 12.7 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KFM75544.1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KFM75544.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM75544.1 - 0.053 13.9 0.0 0.053 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Adeno_IVa2 PF02456.15 KFM75544.1 - 0.067 12.0 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_22 PF13401.6 KFM75544.1 - 0.099 12.9 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFM75544.1 - 0.12 12.4 0.1 0.12 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KFM75544.1 - 0.15 12.0 0.0 0.15 12.0 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KFM75544.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFM75544.1 - 0.19 12.3 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain HSP20 PF00011.21 KFM75545.1 - 1.6e-28 98.9 0.3 1.9e-28 98.6 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFM75545.1 - 1.5e-05 25.0 0.2 2.6e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal Cupredoxin_1 PF13473.6 KFM75545.1 - 0.008 16.3 0.3 0.012 15.7 0.3 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain ArsA_HSP20 PF17886.1 KFM75545.1 - 0.032 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 HSP20-like domain found in ArsA DUF870 PF05912.11 KFM75545.1 - 0.1 12.6 0.1 0.48 10.5 0.0 1.8 1 1 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF870) Hydrolase_4 PF12146.8 KFM75546.1 - 2.4e-10 40.1 0.0 1e-05 25.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM75546.1 - 3.9e-09 36.5 0.2 0.0002 21.1 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM75546.1 - 0.00011 22.9 0.1 0.00028 21.6 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 KFM75546.1 - 0.00019 20.2 0.2 0.026 13.2 0.1 2.3 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KFM75546.1 - 0.0002 20.9 0.0 0.00054 19.5 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 KFM75546.1 - 0.0015 17.5 0.0 0.0015 17.5 0.0 1.6 2 0 0 2 2 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 KFM75546.1 - 0.0063 16.1 0.0 1.2 8.7 0.0 2.5 3 0 0 3 3 3 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KFM75546.1 - 0.033 14.1 0.1 0.066 13.1 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 KFM75546.1 - 0.041 13.5 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 KFM75546.1 - 0.045 13.7 0.0 0.66 9.9 0.0 2.1 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 KFM75546.1 - 0.099 12.4 0.0 0.92 9.2 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Zn_ribbon_recom PF13408.6 KFM75546.1 - 0.11 13.1 1.0 0.22 12.1 1.0 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Lipase_3 PF01764.25 KFM75546.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) DUF1100 PF06500.11 KFM75546.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Atg8 PF02991.16 KFM75547.1 - 8.6e-10 38.7 0.0 8.7e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like CTXphi_pIII-N1 PF16710.5 KFM75547.1 - 0.03 14.5 0.0 0.03 14.4 0.0 1.0 1 0 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Fam20C PF06702.12 KFM75549.1 - 0.00042 20.2 0.1 0.22 11.3 0.1 2.1 2 0 0 2 2 2 2 Golgi casein kinase, C-terminal, Fam20 HTH_Tnp_Tc3_2 PF01498.18 KFM75550.1 - 2.6e-06 27.6 0.1 6.2e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Transposase PAX PF00292.18 KFM75550.1 - 4.1e-06 26.7 0.2 6.6e-06 26.1 0.2 1.3 1 1 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.6 KFM75550.1 - 8.7e-06 25.8 2.5 0.00038 20.5 0.1 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75550.1 - 0.00021 21.0 3.3 0.006 16.3 0.2 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75550.1 - 0.00056 20.5 3.8 0.00056 20.5 3.8 1.6 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM75550.1 - 0.0022 17.9 1.8 0.0061 16.4 0.1 2.2 2 1 0 2 2 2 1 MarR family TrmB PF01978.19 KFM75550.1 - 0.0022 17.8 0.1 0.36 10.8 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_22 PF13309.6 KFM75550.1 - 0.026 14.6 0.1 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 HTH domain HTH_Crp_2 PF13545.6 KFM75550.1 - 0.069 13.1 2.2 0.17 11.9 0.3 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_3 PF01381.22 KFM75550.1 - 0.078 13.1 2.1 1.6 8.8 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix HTH_26 PF13443.6 KFM75550.1 - 0.11 13.0 0.5 3.7 8.1 0.1 2.2 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Lipoprotein_21 PF14041.6 KFM75550.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 LppP/LprE lipoprotein HTH_24 PF13412.6 KFM75550.1 - 0.16 11.6 0.7 4 7.1 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 KFM75550.1 - 0.18 11.6 0.2 0.18 11.6 0.2 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 KFM75550.1 - 0.25 11.2 1.5 0.67 9.8 0.5 2.2 2 2 0 2 2 2 0 PucR C-terminal helix-turn-helix domain RRM_1 PF00076.22 KFM75551.1 - 1.5e-14 53.6 0.1 3.9e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM75551.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif T2SSI PF02501.17 KFM75551.1 - 0.17 12.0 0.1 0.5 10.6 0.0 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I Atrophin-1 PF03154.15 KFM75552.1 - 0.28 9.4 8.1 0.38 9.0 8.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Occludin_ELL PF07303.13 KFM75553.1 - 0.019 15.7 0.2 0.034 14.9 0.2 1.4 1 0 0 1 1 1 0 Occludin homology domain FOP_dimer PF09398.10 KFM75553.1 - 0.033 14.4 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 FOP N terminal dimerisation domain p450 PF00067.22 KFM75554.1 - 3e-34 118.6 0.0 3.4e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3364 PF11844.8 KFM75554.1 - 0.17 12.1 1.3 7.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) MFS_1 PF07690.16 KFM75555.1 - 4.5e-21 75.2 17.3 2.3e-11 43.2 2.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Pep1_7 PF17232.2 KFM75555.1 - 0.011 16.1 1.4 0.03 14.8 1.4 1.8 1 0 0 1 1 1 0 Elicitor peptide 1-7 JmjC PF02373.22 KFM75555.1 - 0.14 12.6 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase GSH_synth_ATP PF03917.17 KFM75557.1 - 6.6e-21 74.5 0.0 7.1e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain Tubulin PF00091.25 KFM75558.1 - 2.8e-46 158.2 0.0 3.2e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFM75558.1 - 6.1e-05 22.8 0.0 7.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFM75558.1 - 0.0027 17.0 0.0 0.0028 16.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin like Peptidase_A17 PF05380.13 KFM75559.1 - 8.6e-51 172.2 0.0 2.3e-50 170.8 0.0 1.8 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 KFM75559.1 - 5.8e-29 100.9 0.1 2.1e-28 99.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF5641 PF18701.1 KFM75559.1 - 1e-20 73.7 2.8 3.4e-20 72.0 2.8 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1758 PF05585.12 KFM75559.1 - 2.7e-16 59.8 0.1 1.9e-15 57.0 0.0 2.5 2 0 0 2 2 2 1 Putative peptidase (DUF1758) rve PF00665.26 KFM75559.1 - 2.3e-14 53.6 0.1 6.3e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KFM75559.1 - 2.4e-08 33.8 0.1 1.3e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KFM75559.1 - 1.6e-07 31.3 2.5 1.6e-07 31.3 2.5 2.8 3 0 0 3 3 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 KFM75559.1 - 0.014 16.0 0.1 0.074 13.7 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease rve_3 PF13683.6 KFM75559.1 - 0.044 13.6 0.1 0.5 10.2 0.0 2.7 3 0 0 3 3 3 0 Integrase core domain RT_RNaseH_2 PF17919.1 KFM75559.1 - 0.1 12.6 0.0 0.62 10.1 0.0 2.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-CCHC_4 PF14392.6 KFM75559.1 - 0.62 9.8 5.1 7.9 6.3 1.0 2.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KFM75559.1 - 1.2 9.0 14.9 0.035 13.9 1.3 2.9 3 0 0 3 3 3 0 Zinc knuckle zf-H2C2 PF09337.10 KFM75559.1 - 4.9 7.5 8.8 0.094 12.9 0.9 2.5 2 0 0 2 2 1 0 H2C2 zinc finger Tubulin_C PF03953.17 KFM75560.1 - 3.3e-18 66.1 0.0 4.8e-18 65.5 0.0 1.3 1 1 0 1 1 1 1 Tubulin C-terminal domain Robl_LC7 PF03259.17 KFM75561.1 - 1.5e-23 82.3 0.0 1.7e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KFM75561.1 - 3.4e-05 23.7 0.0 4.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 vATP-synt_AC39 PF01992.16 KFM75562.1 - 4.2e-115 384.8 0.2 4.7e-115 384.7 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit AdoHcyase PF05221.17 KFM75563.1 - 1.1e-127 425.4 0.0 4.6e-64 216.4 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KFM75563.1 - 3e-85 284.2 1.8 4.5e-85 283.7 1.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM75563.1 - 9.3e-10 38.1 0.2 2.9e-09 36.5 0.1 1.7 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFM75563.1 - 9.8e-06 25.2 0.1 1.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 KFM75563.1 - 0.0024 18.3 0.2 0.0057 17.1 0.1 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.18 KFM75563.1 - 0.016 15.4 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.21 KFM75563.1 - 0.018 14.8 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase THF_DHG_CYH_C PF02882.19 KFM75563.1 - 0.049 13.0 0.2 0.22 10.9 0.2 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FdtA PF05523.11 KFM75563.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 WxcM-like, C-terminal Glycos_transf_2 PF00535.26 KFM75564.1 - 4.5e-31 107.9 0.1 8.4e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KFM75564.1 - 5.9e-05 22.7 0.1 0.00013 21.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RGS-like PF09128.11 KFM75564.1 - 0.077 12.7 0.4 0.17 11.6 0.4 1.5 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Band_7_1 PF13421.6 KFM75564.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Ricin_B_lectin PF00652.22 KFM75565.1 - 3e-12 46.9 0.1 4.5e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFM75565.1 - 6.8e-05 22.5 0.6 0.00013 21.6 0.6 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DDE_3 PF13358.6 KFM75566.1 - 0.015 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75569.1 - 2.2e-16 59.8 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75569.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Sdh5 PF03937.16 KFM75570.1 - 2.3e-26 91.5 0.3 3.4e-26 91.0 0.3 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Ribosomal_S18 PF01084.20 KFM75571.1 - 6e-13 48.8 0.1 1.1e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 PepSY_TM PF03929.16 KFM75572.1 - 0.15 11.7 0.6 0.23 11.1 0.4 1.5 1 1 0 1 1 1 0 PepSY-associated TM region HTH_Tnp_Tc3_2 PF01498.18 KFM75573.1 - 2.6e-14 53.2 1.0 5.7e-14 52.1 1.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75573.1 - 7.3e-14 51.7 0.0 9.9e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4232 PF14016.6 KFM75574.1 - 0.11 12.7 0.2 0.19 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) ABC_membrane PF00664.23 KFM75575.1 - 0.0039 16.9 0.1 0.0054 16.4 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Asp_protease_2 PF13650.6 KFM75577.1 - 4.1e-07 30.5 0.0 4.4e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM75577.1 - 6.7e-06 26.6 0.0 7.2e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease C2-set_2 PF08205.12 KFM75578.1 - 3.6e-10 39.8 0.0 0.0014 18.6 0.0 2.9 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFM75578.1 - 1.2e-09 38.4 0.1 0.0021 18.4 0.0 4.3 3 2 1 4 4 4 2 Immunoglobulin domain Ig_3 PF13927.6 KFM75578.1 - 3.7e-09 37.0 1.0 0.00019 21.9 0.0 4.1 3 1 1 4 4 4 2 Immunoglobulin domain ig PF00047.25 KFM75578.1 - 2.8e-05 24.2 0.1 0.3 11.3 0.0 3.9 4 0 0 4 4 4 1 Immunoglobulin domain VPS13_mid_rpt PF16910.5 KFM75578.1 - 0.0013 18.2 0.2 0.0021 17.5 0.2 1.2 1 0 0 1 1 1 1 Repeating coiled region of VPS13 I-set PF07679.16 KFM75578.1 - 0.002 18.2 0.0 0.062 13.4 0.0 2.8 3 1 0 3 3 3 1 Immunoglobulin I-set domain V-set PF07686.17 KFM75578.1 - 0.04 14.1 0.3 4.2 7.6 0.0 3.4 3 1 1 4 4 4 0 Immunoglobulin V-set domain zf-C2H2 PF00096.26 KFM75580.1 - 2e-38 128.7 72.7 4.5e-07 30.0 0.6 9.9 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM75580.1 - 4.4e-31 105.9 62.1 6.4e-08 32.7 1.8 10.6 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM75580.1 - 5.6e-24 82.8 75.3 0.0015 19.2 1.2 10.5 11 0 0 11 11 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75580.1 - 1.2e-10 41.4 39.9 0.0078 16.5 0.4 8.7 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM75580.1 - 5.9e-09 35.5 46.9 0.00058 19.6 2.4 8.3 7 2 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM75580.1 - 1.3e-05 24.9 47.7 0.079 12.7 0.2 9.0 8 1 1 9 9 9 5 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM75580.1 - 4.6e-05 23.3 52.2 0.16 12.0 1.3 8.8 8 0 0 8 8 8 4 C2H2-type zinc finger zf-BED PF02892.15 KFM75580.1 - 0.00054 19.9 46.8 0.019 15.0 0.3 7.5 3 3 3 6 6 6 3 BED zinc finger GAGA PF09237.11 KFM75580.1 - 0.00076 19.2 19.3 0.058 13.2 0.2 6.2 3 2 3 6 6 6 2 GAGA factor zf-Di19 PF05605.12 KFM75580.1 - 0.00084 19.6 3.9 0.00084 19.6 3.9 5.7 2 2 5 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFM75580.1 - 0.0013 19.0 35.7 0.0081 16.4 3.0 4.3 2 2 2 4 4 4 2 C2H2-type zinc ribbon zf-met PF12874.7 KFM75580.1 - 0.0018 18.6 34.3 0.02 15.3 0.4 7.8 7 0 0 7 7 7 3 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KFM75580.1 - 0.0064 16.6 1.1 0.0064 16.6 1.1 6.2 5 1 1 6 6 6 1 Zinc ribbon domain Nudix_N_2 PF14803.6 KFM75580.1 - 0.39 10.7 12.8 0.52 10.3 0.9 4.7 4 0 0 4 4 4 0 Nudix N-terminal zf-C2HC_2 PF13913.6 KFM75580.1 - 2.2 8.3 33.4 1 9.3 2.1 6.7 6 0 0 6 6 6 0 zinc-finger of a C2HC-type BolA PF01722.18 KFM75580.1 - 2.2 8.6 5.4 45 4.4 0.4 4.0 3 1 0 3 3 3 0 BolA-like protein ADK_lid PF05191.14 KFM75580.1 - 2.6 8.1 19.9 6 6.9 0.3 5.9 4 2 0 4 4 3 0 Adenylate kinase, active site lid PyrI_C PF02748.15 KFM75580.1 - 5.3 7.0 26.9 0.24 11.3 0.9 6.0 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM75581.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75581.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75581.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75581.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75581.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain E1_DerP2_DerF2 PF02221.15 KFM75582.1 - 1.5e-29 103.1 3.1 1.8e-29 102.9 3.1 1.0 1 0 0 1 1 1 1 ML domain Cu-oxidase_3 PF07732.15 KFM75582.1 - 0.017 15.1 0.0 0.17 11.9 0.0 2.0 1 1 0 2 2 2 0 Multicopper oxidase E1_DerP2_DerF2 PF02221.15 KFM75583.1 - 1.2e-17 64.6 2.8 1.4e-17 64.4 2.8 1.1 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 KFM75584.1 - 6.1e-22 78.5 3.8 7.7e-22 78.2 3.8 1.0 1 0 0 1 1 1 1 ML domain Cu-oxidase_3 PF07732.15 KFM75584.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase HTH_Tnp_Tc3_2 PF01498.18 KFM75585.1 - 2.6e-16 59.6 2.8 4.9e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75585.1 - 1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75585.1 - 1.7e-07 30.9 1.2 6.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75585.1 - 0.0023 17.7 0.6 0.0067 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75585.1 - 1.7 9.3 15.7 0.11 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Sushi PF00084.20 KFM75586.1 - 1.1e-42 144.5 32.4 1.9e-11 44.4 0.5 9.4 9 0 0 9 9 9 8 Sushi repeat (SCR repeat) zf-MIZ PF02891.20 KFM75586.1 - 0.0059 16.3 0.2 2.5 7.9 0.0 3.4 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger GTP1_OBG PF01018.22 KFM75586.1 - 0.087 12.4 0.0 41 3.7 0.0 3.2 3 0 0 3 3 3 0 GTP1/OBG HECA PF15353.6 KFM75586.1 - 0.095 13.0 0.4 0.58 10.4 0.0 2.5 3 0 0 3 3 3 0 Headcase protein family homologue rve PF00665.26 KFM75587.1 - 5.4e-09 36.3 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain ATG11 PF10377.9 KFM75587.1 - 0.05 13.7 0.1 0.083 13.0 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 Sushi PF00084.20 KFM75588.1 - 7.4e-42 141.8 47.2 0.00012 22.6 0.1 11.4 11 0 0 11 11 11 10 Sushi repeat (SCR repeat) Ig_3 PF13927.6 KFM75588.1 - 0.0075 16.8 5.1 0.32 11.6 0.1 4.4 3 1 1 4 4 4 1 Immunoglobulin domain Sushi PF00084.20 KFM75589.1 - 2.6e-37 127.2 18.7 2.2e-11 44.2 0.1 4.1 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) HRM PF02793.22 KFM75589.1 - 2.8e-06 27.5 6.9 0.6 10.4 0.1 3.6 3 0 0 3 3 3 3 Hormone receptor domain cEGF PF12662.7 KFM75589.1 - 2.9 7.9 13.6 6.1 6.9 0.2 4.5 4 1 1 5 5 5 0 Complement Clr-like EGF-like zf-H2C2_2 PF13465.6 KFM75590.1 - 2.9e-83 270.9 97.4 2.6e-08 33.9 1.0 14.1 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75590.1 - 4.5e-65 212.6 102.0 3.3e-06 27.3 1.9 13.1 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75590.1 - 1.4e-48 159.3 102.8 8.8e-05 23.0 1.0 13.1 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75590.1 - 1.9e-25 88.5 59.1 0.0029 17.9 0.1 13.3 11 2 2 13 13 13 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM75590.1 - 1e-21 76.4 79.2 0.0058 16.6 0.6 13.3 13 0 0 13 13 13 10 C2H2-type zinc finger zf-met PF12874.7 KFM75590.1 - 6.4e-21 74.0 79.6 0.0017 18.7 0.4 13.4 13 0 0 13 13 13 9 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM75590.1 - 5.1e-14 51.7 65.4 0.044 13.5 0.4 12.8 12 0 0 12 12 12 7 C2H2-type zinc-finger domain zf-MYST PF17772.1 KFM75590.1 - 1.1e-11 44.1 45.5 0.13 11.9 0.2 11.6 6 4 6 12 12 12 4 MYST family zinc finger domain ADK_lid PF05191.14 KFM75590.1 - 6.5e-09 35.6 38.3 0.01 15.8 0.6 8.6 3 3 5 8 8 8 5 Adenylate kinase, active site lid GAGA PF09237.11 KFM75590.1 - 3e-08 33.3 22.3 0.25 11.2 0.1 7.5 4 2 5 9 9 8 3 GAGA factor FYVE PF01363.21 KFM75590.1 - 4e-08 33.3 58.3 0.0033 17.5 5.5 6.9 2 2 3 6 6 6 5 FYVE zinc finger zf-CHCC PF10276.9 KFM75590.1 - 1.7e-07 31.2 26.0 8.6 6.5 0.1 11.6 12 0 0 12 12 12 0 Zinc-finger domain DUF2256 PF10013.9 KFM75590.1 - 1.8e-06 28.0 47.8 4.7 7.4 0.2 12.2 12 0 0 12 12 12 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-RRPl_C4 PF17026.5 KFM75590.1 - 1.8e-05 24.8 34.8 0.21 11.7 0.5 5.9 1 1 5 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type DUF3268 PF11672.8 KFM75590.1 - 7.3e-05 23.1 26.8 0.77 10.1 2.6 5.6 5 2 0 5 5 5 3 zinc-finger-containing domain zf-C2H2_2 PF12756.7 KFM75590.1 - 0.00023 21.5 75.8 0.94 9.8 2.6 11.8 1 1 11 12 12 12 4 C2H2 type zinc-finger (2 copies) zf-HIT PF04438.16 KFM75590.1 - 0.00032 20.5 60.8 0.63 10.0 0.3 12.0 12 0 0 12 12 12 2 HIT zinc finger XPA_N PF01286.18 KFM75590.1 - 0.00048 20.1 42.5 5.7 7.1 0.0 11.9 12 0 0 12 12 12 1 XPA protein N-terminal TRAF6_Z2 PF18048.1 KFM75590.1 - 0.01 15.9 51.9 0.067 13.3 0.8 10.5 12 0 0 12 12 12 0 TNF receptor-associated factor 6 zinc finger 2 DUF4121 PF13497.6 KFM75590.1 - 0.011 14.9 0.7 5.8 6.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4121) zf-C2H2_11 PF16622.5 KFM75590.1 - 0.039 13.7 0.9 0.039 13.7 0.9 10.3 12 0 0 12 12 12 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM75590.1 - 0.046 13.6 42.3 1.4 8.9 0.0 10.5 12 0 0 12 12 10 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM75590.1 - 0.047 14.4 44.1 1.4 9.7 0.7 6.8 1 1 4 6 6 6 0 zinc-ribbon family IGPD PF00475.18 KFM75590.1 - 0.068 13.5 5.8 3.5 7.9 0.2 4.2 2 2 3 5 5 5 0 Imidazoleglycerol-phosphate dehydratase Flag1_repress PF03614.13 KFM75590.1 - 0.09 12.6 6.0 5.8 6.7 0.1 4.0 1 1 5 6 6 6 0 Repressor of phase-1 flagellin Cript PF10235.9 KFM75590.1 - 0.096 13.3 45.4 0.16 12.5 1.2 7.4 4 4 3 8 8 8 0 Microtubule-associated protein CRIPT HNH PF01844.23 KFM75590.1 - 0.28 11.4 55.5 9.3 6.5 0.2 12.0 12 0 0 12 12 12 0 HNH endonuclease YyzF PF14116.6 KFM75590.1 - 1.8 8.6 36.1 13 5.9 0.1 11.0 12 0 0 12 12 12 0 YyzF-like protein zf-DBF PF07535.12 KFM75590.1 - 1.9 8.7 42.8 12 6.1 0.4 11.3 12 0 0 12 12 12 0 DBF zinc finger GATA PF00320.27 KFM75590.1 - 9.2 6.0 17.8 24 4.6 0.1 7.1 10 0 0 10 10 8 0 GATA zinc finger zf-H2C2_2 PF13465.6 KFM75591.1 - 9.1e-43 142.9 48.3 5.6e-08 32.9 0.7 8.2 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75591.1 - 2.7e-28 96.8 59.9 5.4e-05 23.4 1.4 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75591.1 - 2e-24 84.1 52.4 0.0012 19.5 0.6 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 KFM75591.1 - 3.1e-17 62.3 44.7 0.0027 18.0 3.2 7.7 8 0 0 8 8 7 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM75591.1 - 2e-10 40.7 33.5 0.059 13.7 1.2 7.6 8 0 0 8 8 7 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM75591.1 - 7.3e-10 38.4 29.1 0.3 10.9 0.9 7.4 7 0 0 7 7 7 6 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM75591.1 - 4.4e-09 36.1 44.0 0.14 12.2 0.8 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM75591.1 - 1.6e-05 24.7 28.5 0.31 11.0 0.0 6.8 7 0 0 7 7 7 4 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM75591.1 - 0.00013 21.9 14.5 0.11 12.5 0.1 4.7 2 2 3 5 5 5 3 Adenylate kinase, active site lid zf-CHCC PF10276.9 KFM75591.1 - 0.00046 20.2 10.7 14 5.9 0.0 6.6 7 0 0 7 7 7 0 Zinc-finger domain BolA PF01722.18 KFM75591.1 - 0.01 16.1 6.9 2.4 8.5 0.2 4.3 2 1 2 4 4 4 0 BolA-like protein GAGA PF09237.11 KFM75591.1 - 0.013 15.3 0.1 0.013 15.3 0.1 5.1 3 2 3 6 6 6 0 GAGA factor FYVE PF01363.21 KFM75591.1 - 0.043 13.9 38.2 1.1 9.5 3.2 4.7 1 1 3 4 4 4 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KFM75591.1 - 0.11 12.3 42.7 0.31 10.8 0.8 7.1 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-DBF PF07535.12 KFM75591.1 - 0.2 11.8 22.6 20 5.4 0.4 6.7 6 1 1 7 7 7 0 DBF zinc finger zf-C2H2_2 PF12756.7 KFM75591.1 - 0.43 11.0 40.3 0.71 10.2 3.8 6.7 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) HNH PF01844.23 KFM75591.1 - 0.63 10.3 26.4 14 6.0 0.1 7.0 5 2 2 8 8 8 0 HNH endonuclease zf-Sec23_Sec24 PF04810.15 KFM75591.1 - 1.1 9.3 26.3 16 5.6 0.2 6.9 6 1 1 7 7 7 0 Sec23/Sec24 zinc finger YyzF PF14116.6 KFM75591.1 - 1.5 8.9 23.9 6.3 6.9 0.0 6.7 7 0 0 7 7 7 0 YyzF-like protein zinc_ribbon_15 PF17032.5 KFM75591.1 - 2.2 9.1 23.0 2.3 9.0 0.7 3.8 1 1 4 5 5 5 0 zinc-ribbon family zf-HIT PF04438.16 KFM75591.1 - 3.7 7.5 35.2 13 5.7 0.3 7.1 7 0 0 7 7 7 0 HIT zinc finger SVS_QK PF10578.9 KFM75591.1 - 5.6 7.8 6.7 18 6.3 0.0 3.3 3 0 0 3 3 3 0 Seminal vesicle protein repeat Bromodomain PF00439.25 KFM75592.1 - 3.1e-23 81.6 0.0 1.1e-22 79.8 0.0 2.0 2 0 0 2 2 2 1 Bromodomain PHD PF00628.29 KFM75592.1 - 9.4e-21 73.5 24.6 2.3e-11 43.4 7.8 3.3 3 0 0 3 3 3 2 PHD-finger MBD PF01429.19 KFM75592.1 - 6.9e-19 67.3 0.1 1.7e-18 66.0 0.1 1.8 1 0 0 1 1 1 1 Methyl-CpG binding domain WSD PF15613.6 KFM75592.1 - 7.7e-10 39.1 0.1 2.2e-05 24.9 0.0 5.6 5 1 0 5 5 5 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KFM75592.1 - 1.5e-09 38.0 4.8 1e-08 35.3 4.9 2.2 2 0 0 2 2 2 1 DDT domain PHD_2 PF13831.6 KFM75592.1 - 0.0017 17.8 8.4 0.11 12.1 1.0 2.7 2 0 0 2 2 2 2 PHD-finger WHIM1 PF15612.6 KFM75592.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Zf_RING PF16744.5 KFM75592.1 - 0.021 14.9 9.8 0.2 11.8 0.5 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger DUF2024 PF09630.10 KFM75592.1 - 0.24 11.3 1.2 0.7 9.8 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) zf-RanBP PF00641.18 KFM75592.1 - 0.88 8.9 6.4 2.7 7.4 0.6 3.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PRP1_N PF06424.12 KFM75593.1 - 1.3e-57 194.3 9.2 2.1e-57 193.7 9.2 1.3 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KFM75593.1 - 1.1e-10 41.4 3.0 0.009 16.8 0.4 5.7 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFM75593.1 - 3.8e-07 30.0 0.1 0.02 15.3 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM75593.1 - 5.7e-05 23.6 0.0 0.71 10.4 0.0 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM75593.1 - 0.02 15.0 1.3 32 5.0 0.0 4.8 6 1 1 7 7 7 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KFM75593.1 - 0.2 10.7 5.1 3 6.9 0.2 2.6 2 1 1 3 3 3 0 NRDE-2, necessary for RNA interference Enkurin PF13864.6 KFM75593.1 - 0.49 10.9 9.8 0.26 11.7 7.2 1.9 2 0 0 2 2 2 0 Calmodulin-binding VIR_N PF15912.5 KFM75593.1 - 1.7 8.2 10.0 4.7 6.7 10.4 1.5 2 0 0 2 2 2 0 Virilizer, N-terminal Diphthamide_syn PF01866.17 KFM75594.1 - 4.9e-92 308.6 1.2 6e-92 308.3 1.2 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF2400 PF09674.10 KFM75594.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Hyd_WA PF06462.12 KFM75595.1 - 4.7e-15 55.3 0.0 1.4e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Propeller PH PF00169.29 KFM75596.1 - 1e-06 29.2 0.0 2.1e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 PH domain DDE_3 PF13358.6 KFM75597.1 - 1e-07 31.8 0.0 1.3e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Leg1 PF05612.12 KFM75597.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Leg1 Clat_adaptor_s PF01217.20 KFM75598.1 - 0.0014 18.6 0.7 0.0021 18.0 0.7 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain PIF1 PF05970.14 KFM75600.1 - 2.8e-14 53.1 0.0 3.2e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase WASH-7_N PF14745.6 KFM75601.1 - 0.016 13.7 0.0 0.02 13.4 0.0 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal DDE_1 PF03184.19 KFM75601.1 - 0.02 14.5 0.4 0.079 12.6 0.2 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease KCNQC3-Ank-G_bd PF11956.8 KFM75601.1 - 0.051 13.9 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 LMBR1 PF04791.16 KFM75602.1 - 7.8e-08 31.7 2.3 7.8e-08 31.7 2.3 1.6 2 0 0 2 2 2 1 LMBR1-like membrane protein LMBR1 PF04791.16 KFM75603.1 - 1.4e-10 40.7 3.5 1.5e-10 40.7 3.5 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein LMBR1 PF04791.16 KFM75604.1 - 3.4e-100 336.4 5.6 3.8e-100 336.2 5.6 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4096 PF13340.6 KFM75604.1 - 0.066 13.4 2.0 0.46 10.8 0.2 2.9 2 1 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) HTH_Tnp_Tc3_2 PF01498.18 KFM75605.1 - 4.4e-16 58.9 3.5 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75605.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75605.1 - 3.3e-07 30.0 1.8 8.1e-07 28.7 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75605.1 - 0.0012 18.6 0.6 0.0033 17.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75605.1 - 1.6 9.4 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Sushi PF00084.20 KFM75606.1 - 1.2e-31 109.0 15.5 3.8e-08 33.8 0.1 5.7 4 1 1 5 5 5 5 Sushi repeat (SCR repeat) HRM PF02793.22 KFM75606.1 - 0.0027 18.0 12.5 0.025 14.8 0.0 5.2 5 0 0 5 5 5 2 Hormone receptor domain HTH_Tnp_Tc3_1 PF11427.8 KFM75608.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase DUF4061 PF13270.6 KFM75609.1 - 1.2e-17 64.0 0.5 1.2e-17 64.0 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4061) Bacteroid_pep PF14406.6 KFM75609.1 - 0.09 13.2 1.3 0.14 12.5 0.3 1.9 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Bacteroidetes DUF3796 PF12676.7 KFM75610.1 - 0.057 13.8 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) THAP PF05485.12 KFM75611.1 - 1.3e-08 35.7 2.9 1.5e-08 35.5 2.9 1.1 1 0 0 1 1 1 1 THAP domain COesterase PF00135.28 KFM75613.1 - 1.2e-103 347.7 0.0 1.4e-103 347.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM75613.1 - 0.00017 21.5 0.5 0.0021 18.0 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3920 PF13058.6 KFM75613.1 - 0.16 12.2 0.2 0.45 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) DUF5338 PF17273.2 KFM75613.1 - 0.19 11.8 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5338) LRR_4 PF12799.7 KFM75615.1 - 3.4e-10 40.0 27.8 0.0017 18.7 0.0 5.6 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM75615.1 - 4.7e-10 39.2 2.1 4.7e-10 39.2 2.1 2.8 2 1 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KFM75615.1 - 1.4e-08 34.3 23.2 0.00013 21.6 4.7 4.6 4 1 1 5 5 5 3 Leucine rich repeat PX PF00787.24 KFM75615.1 - 0.00064 19.7 0.2 0.0012 18.8 0.2 1.4 1 0 0 1 1 1 1 PX domain LRR_6 PF13516.6 KFM75615.1 - 0.038 14.0 16.6 17 5.8 0.0 7.1 6 1 1 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 KFM75615.1 - 5.1 8.0 21.3 14 6.7 0.0 7.5 5 1 0 5 5 5 0 Leucine Rich Repeat HOOK PF05622.12 KFM75616.1 - 0.00012 20.4 1.1 0.00014 20.2 1.1 1.0 1 0 0 1 1 1 1 HOOK protein GvpG PF05120.12 KFM75616.1 - 0.0089 16.0 1.7 0.011 15.7 1.7 1.2 1 0 0 1 1 1 1 Gas vesicle protein G GTP_EFTU PF00009.27 KFM75617.1 - 0.021 14.3 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NOZZLE PF08744.10 KFM75618.1 - 9.7e-14 51.6 13.1 11 5.3 0.1 11.4 1 1 6 10 10 10 10 Plant transcription factor NOZZLE Pep_M12B_propep PF01562.19 KFM75619.1 - 1.2e-07 32.0 0.1 1.8e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Collagen PF01391.18 KFM75620.1 - 6.4e-120 391.0 381.7 1.2e-10 40.9 25.9 15.2 2 2 11 13 13 13 13 Collagen triple helix repeat (20 copies) C4 PF01413.19 KFM75620.1 - 4.9e-82 271.6 2.3 2.1e-43 147.2 0.1 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen FAM181 PF15238.6 KFM75621.1 - 1.2e-06 28.6 2.9 1.4e-06 28.4 2.9 1.1 1 0 0 1 1 1 1 FAM181 WW PF00397.26 KFM75621.1 - 0.064 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 WW domain ABC_membrane PF00664.23 KFM75623.1 - 3.9e-74 249.8 23.8 2.7e-38 132.2 3.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFM75623.1 - 8e-54 181.9 0.0 7.4e-30 104.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFM75623.1 - 1.1e-08 34.8 1.0 0.019 14.4 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFM75623.1 - 6.8e-06 26.1 0.1 0.0094 16.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM75623.1 - 7.8e-06 25.9 0.0 0.034 14.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFM75623.1 - 2.2e-05 24.9 0.0 0.26 11.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KFM75623.1 - 7.5e-05 22.7 0.0 1.5 8.6 0.0 3.8 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFM75623.1 - 0.00028 21.2 0.5 1.2 9.4 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFM75623.1 - 0.0026 17.5 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_5 PF07728.14 KFM75623.1 - 0.0083 16.1 1.2 16 5.5 0.1 4.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KFM75623.1 - 0.0098 15.4 0.3 3.9 6.9 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 KFM75623.1 - 0.017 15.2 0.6 3.9 7.5 0.2 2.6 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 KFM75623.1 - 0.029 13.6 0.3 2.8 7.1 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_23 PF13476.6 KFM75623.1 - 0.049 14.1 2.4 8.5 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KFM75623.1 - 0.053 13.1 0.4 2.9 7.4 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KFM75623.1 - 0.073 13.0 1.3 2.4 8.1 0.2 2.5 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 KFM75623.1 - 0.11 12.6 0.0 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 KFM75623.1 - 0.16 11.7 0.7 6.4 6.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KFM75623.1 - 0.17 12.3 0.2 0.97 9.9 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KFM75623.1 - 0.19 11.9 1.1 7.8 6.7 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 KFM75624.1 - 3.9e-41 141.2 0.0 4.5e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM75624.1 - 4.4e-24 85.2 0.0 5.1e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM75624.1 - 3.4e-08 33.1 0.0 4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM75624.1 - 0.00013 21.0 0.1 0.00016 20.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM75624.1 - 0.00066 19.1 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFM75624.1 - 0.0035 16.5 0.1 0.0047 16.0 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KFM75624.1 - 0.018 15.0 0.3 0.031 14.2 0.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFM75624.1 - 0.083 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 KFM75624.1 - 0.17 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase KELK PF15796.5 KFM75625.1 - 1.9e-30 105.1 16.7 1.9e-30 105.1 16.7 6.6 5 1 2 7 7 7 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase C1_1 PF00130.22 KFM75625.1 - 1.9e-11 43.7 5.2 4.1e-11 42.6 5.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DMPK_coil PF08826.10 KFM75625.1 - 4e-06 26.8 7.5 4e-06 26.8 7.5 8.0 7 1 1 8 8 8 2 DMPK coiled coil domain like Myosin_tail_1 PF01576.19 KFM75625.1 - 2.5e-05 22.3 86.0 2.5e-05 22.3 86.0 2.8 1 1 1 2 2 2 1 Myosin tail Sod_Ni PF09055.11 KFM75625.1 - 0.014 16.0 3.9 0.014 16.0 3.9 3.1 3 1 0 3 3 3 0 Nickel-containing superoxide dismutase ERM PF00769.19 KFM75625.1 - 0.046 13.5 94.8 0.71 9.6 16.6 4.2 1 1 3 4 4 4 0 Ezrin/radixin/moesin family DUF3138 PF11336.8 KFM75625.1 - 5.4 5.5 4.5 3.2 6.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) CNH PF00780.22 KFM75626.1 - 1e-50 172.9 0.0 1.5e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 CNH domain PBD PF00786.28 KFM75626.1 - 0.0016 18.8 0.0 0.0045 17.3 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH_3 PF14593.6 KFM75626.1 - 0.19 11.9 0.1 26 5.0 0.0 3.1 3 0 0 3 3 3 0 PH domain MutL_C PF08676.11 KFM75628.1 - 1.4e-09 37.9 0.2 2.5e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DUF2362 PF10154.9 KFM75628.1 - 0.012 14.5 0.7 0.012 14.5 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2362) WW PF00397.26 KFM75628.1 - 0.04 14.0 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 WW domain HATPase_c PF02518.26 KFM75629.1 - 2e-10 41.1 0.0 3.3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFM75629.1 - 2.4e-09 37.2 0.0 3.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_CodY PF08222.11 KFM75629.1 - 0.013 15.0 0.1 0.038 13.6 0.1 1.8 1 0 0 1 1 1 0 CodY helix-turn-helix domain SelB-wing_1 PF09105.10 KFM75629.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix zf-C2HC_2 PF13913.6 KFM75630.1 - 4.1e-19 68.0 13.0 1.3e-09 37.7 1.5 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM75630.1 - 0.0086 16.2 1.0 1.4 9.1 0.1 2.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.19 KFM75630.1 - 0.009 16.0 2.3 0.44 10.6 0.5 2.4 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_4 PF13894.6 KFM75630.1 - 0.011 16.5 6.8 1.4 9.9 1.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM75630.1 - 0.018 15.4 1.4 3.6 8.2 0.1 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type YhfH PF14149.6 KFM75630.1 - 0.077 13.0 5.6 1.8 8.6 1.1 2.4 2 0 0 2 2 2 0 YhfH-like protein zf-CpG_bind_C PF12269.8 KFM75630.1 - 0.082 12.7 0.0 0.082 12.7 0.0 3.1 3 1 1 4 4 4 0 CpG binding protein zinc finger C terminal domain zf-C2H2_11 PF16622.5 KFM75630.1 - 0.16 11.8 1.8 12 5.8 0.4 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-CHCC PF10276.9 KFM75630.1 - 0.17 12.0 3.5 4.4 7.4 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger domain Rad50_zn_hook PF04423.14 KFM75630.1 - 0.39 10.6 7.5 4.6 7.2 0.4 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif FYVE PF01363.21 KFM75630.1 - 0.9 9.7 5.3 8.9 6.5 1.0 2.5 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 KFM75630.1 - 0.91 9.6 3.7 8.2 6.5 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KFM75630.1 - 0.98 9.2 4.7 3.4 7.5 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.6 KFM75630.1 - 1.2 9.1 4.4 6.8 6.7 0.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 KFM75630.1 - 6.5 7.1 6.3 9.4 6.6 1.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HTH_Tnp_Tc3_2 PF01498.18 KFM75632.1 - 2.3e-16 59.8 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75632.1 - 7.9e-14 51.6 0.0 1.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75633.1 - 5.2e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75633.1 - 1.2e-13 51.0 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75633.1 - 2.2e-07 30.5 1.2 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75633.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75633.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Fasciclin PF02469.22 KFM75634.1 - 1.2e-09 38.5 0.1 5.8e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Fasciclin domain PSRP-3_Ycf65 PF04839.13 KFM75634.1 - 0.044 14.0 0.4 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Tnp_P_element PF12017.8 KFM75635.1 - 3.2e-17 62.7 0.0 3.3e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Transposase protein BTB PF00651.31 KFM75636.1 - 7.1e-42 142.1 0.7 5.6e-26 91.0 0.5 2.8 2 1 0 2 2 2 2 BTB/POZ domain MATH PF00917.26 KFM75636.1 - 4e-09 36.6 0.1 5.9e-06 26.4 0.0 2.7 2 0 0 2 2 2 2 MATH domain DUF4217 PF13959.6 KFM75636.1 - 0.052 13.8 0.2 6.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) Complex1_LYR_1 PF13232.6 KFM75637.1 - 0.0064 17.1 0.3 0.011 16.3 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Ank_2 PF12796.7 KFM75640.1 - 6.4e-33 113.2 0.9 1.9e-13 50.8 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFM75640.1 - 3.5e-29 99.9 1.8 2.5e-05 24.5 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KFM75640.1 - 6.1e-29 100.0 2.9 1.9e-09 37.8 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM75640.1 - 3.7e-25 85.2 3.3 0.0005 20.3 0.0 7.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFM75640.1 - 1.3e-21 76.3 0.1 0.00025 21.3 0.0 5.3 4 1 1 5 5 5 5 Ankyrin repeats (many copies) ORC3_N PF07034.11 KFM75640.1 - 0.016 14.3 0.0 3.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus DCB PF16213.5 KFM75640.1 - 0.017 14.8 0.0 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 ERO1 PF04137.15 KFM75641.1 - 2.6e-99 332.8 0.0 2.9e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Methyltransf_16 PF10294.9 KFM75642.1 - 2e-07 30.9 0.0 2.6e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase zf-C2H2 PF00096.26 KFM75643.1 - 5.5e-19 67.5 28.1 1.8e-06 28.0 3.5 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75643.1 - 4.5e-16 58.2 26.4 1.3e-05 25.6 1.9 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM75643.1 - 4.6e-16 58.4 33.4 1.2e-05 25.5 0.6 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-met PF12874.7 KFM75643.1 - 2.7e-07 30.8 18.6 0.0058 17.0 0.3 4.2 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM75643.1 - 3.4e-06 27.2 18.3 0.008 16.4 0.0 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM75643.1 - 4.9e-05 23.0 17.5 0.0032 17.2 1.1 3.7 3 1 0 3 3 3 2 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM75643.1 - 0.0019 17.9 1.5 0.0019 17.9 1.5 4.9 4 2 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_3 PF13878.6 KFM75643.1 - 4.7 7.1 19.1 0.19 11.6 3.3 3.9 2 2 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_6 PF13912.6 KFM75643.1 - 4.7 7.3 24.5 0.52 10.4 2.2 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger DUF2180 PF09947.9 KFM75643.1 - 7.3 6.6 8.2 2.4 8.2 0.1 2.9 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-MYST PF17772.1 KFM75643.1 - 8.9 6.0 17.3 2.9 7.6 0.5 3.9 4 0 0 4 4 4 0 MYST family zinc finger domain Actin_micro PF17003.5 KFM75643.1 - 9.1 5.3 8.2 0.89 8.7 2.5 2.0 1 1 1 2 2 2 0 Putative actin-like family PAC3 PF10178.9 KFM75646.1 - 8.4e-13 48.3 0.1 1.1e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Peptidase_S28 PF05577.12 KFM75647.1 - 4.9e-98 328.7 0.6 5.8e-98 328.5 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 KFM75647.1 - 8.7e-07 28.5 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KFM75647.1 - 1e-06 28.2 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KFM75647.1 - 9.4e-05 22.2 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM75647.1 - 0.0001 21.9 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFM75647.1 - 0.00036 21.2 0.0 0.00057 20.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.11 KFM75647.1 - 0.00047 18.9 0.1 0.00079 18.2 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Cbl_N PF02262.16 KFM75648.1 - 6e-57 191.1 1.6 7.6e-57 190.7 1.6 1.1 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N2 PF02761.14 KFM75648.1 - 0.0045 17.7 0.9 0.014 16.1 0.2 2.2 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain DUF851 PF05867.11 KFM75648.1 - 0.018 14.5 1.3 0.17 11.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF851) Pet191_N PF10203.9 KFM75648.1 - 0.02 15.2 0.3 0.039 14.3 0.3 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cbl_N3 PF02762.14 KFM75649.1 - 3.4e-38 129.3 0.0 4.7e-38 128.9 0.0 1.2 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 KFM75649.1 - 6.3e-22 78.1 0.8 1.1e-21 77.4 0.8 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Leader_CPA1 PF08252.11 KFM75649.1 - 0.59 9.6 2.2 0.51 9.8 0.3 1.9 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide Prok-RING_4 PF14447.6 KFM75650.1 - 1.3e-14 53.7 5.2 2.4e-14 52.9 5.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFM75650.1 - 1.6e-12 47.0 4.1 2.8e-12 46.3 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM75650.1 - 2.2e-09 37.0 7.1 4.7e-09 36.0 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM75650.1 - 1.9e-07 31.3 8.1 3.6e-07 30.4 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM75650.1 - 7.4e-05 22.5 7.7 7.4e-05 22.5 7.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM75650.1 - 0.00017 21.6 4.9 0.0006 19.8 5.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM75650.1 - 0.00017 21.4 5.9 0.00034 20.5 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KFM75650.1 - 0.0074 16.1 6.9 0.017 14.9 6.9 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFM75650.1 - 0.031 14.5 5.8 0.068 13.5 5.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-UDP PF14569.6 KFM75650.1 - 0.063 13.4 3.3 0.2 11.8 3.3 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger UBA PF00627.31 KFM75650.1 - 0.11 12.4 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 UBA/TS-N domain zf-C3HC4_4 PF15227.6 KFM75650.1 - 0.26 11.5 8.1 0.6 10.3 8.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 KFM75651.1 - 1.9e-13 50.4 0.1 2.4e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM75651.1 - 1.8e-09 37.3 0.2 2.3e-09 36.9 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM75652.1 - 4.2e-14 52.5 0.0 4.9e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM75652.1 - 1.1e-10 41.2 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1682 PF07946.14 KFM75654.1 - 3e-99 332.3 6.6 3.9e-99 331.9 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RPN2_C PF18004.1 KFM75654.1 - 0.003 17.5 12.7 0.003 17.5 12.7 1.8 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain LRR_9 PF14580.6 KFM75655.1 - 3.5e-09 36.4 7.2 6.3e-06 25.8 0.1 3.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 KFM75655.1 - 7.9e-08 32.0 9.4 0.00013 21.7 4.1 4.1 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM75655.1 - 4.6e-07 30.1 21.8 0.022 15.2 2.8 5.7 1 1 5 7 7 7 5 Leucine Rich repeats (2 copies) ubiquitin PF00240.23 KFM75655.1 - 0.015 15.0 0.1 0.048 13.4 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin family KHA PF11834.8 KFM75655.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel LRR_6 PF13516.6 KFM75655.1 - 3.4 8.0 11.7 30 5.0 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat HTH_Tnp_Tc3_2 PF01498.18 KFM75657.1 - 4.5e-16 58.8 3.7 4.6e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75657.1 - 9e-14 51.5 0.0 1.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Co_AT_N PF12557.8 KFM75657.1 - 0.5 10.4 4.9 3.1 7.8 0.0 2.8 3 0 0 3 3 3 0 Cob(I)alamin adenosyltransferase N terminal DnaJ PF00226.31 KFM75658.1 - 1.2e-25 89.4 1.1 1.7e-25 88.9 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain CaMBD PF02888.16 KFM75659.1 - 6.5e-34 116.0 3.3 1e-33 115.3 3.3 1.3 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 KFM75659.1 - 1.2e-10 41.2 1.7 2.1e-10 40.4 1.7 1.4 1 0 0 1 1 1 1 Ion channel HTH_Tnp_Tc3_2 PF01498.18 KFM75660.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75660.1 - 7.4e-14 51.7 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-RING_2 PF13639.6 KFM75662.1 - 1.2e-11 44.8 7.3 1.2e-11 44.8 7.3 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM75662.1 - 7.9e-10 38.4 6.7 2e-09 37.1 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM75662.1 - 3.7e-08 33.1 4.9 1.1e-07 31.5 4.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM75662.1 - 1.1e-07 31.6 2.1 2.2e-07 30.6 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM75662.1 - 1.7e-07 31.4 8.8 1.5e-06 28.4 8.8 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM75662.1 - 2.1e-07 30.9 3.1 6.6e-07 29.2 3.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM75662.1 - 2.7e-06 27.2 3.0 7.5e-06 25.8 3.0 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM75662.1 - 2e-05 24.4 4.6 2e-05 24.4 4.6 2.2 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KFM75662.1 - 3.8e-05 23.2 5.0 0.00014 21.4 5.0 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFM75662.1 - 3.9e-05 23.7 1.5 0.00012 22.2 1.3 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFM75662.1 - 5.8e-05 22.8 2.8 5.8e-05 22.8 2.8 2.5 2 0 0 2 2 1 1 RING-like zinc finger TRC8_N PF13705.6 KFM75662.1 - 0.00035 19.6 5.8 0.00044 19.3 5.8 1.2 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-ANAPC11 PF12861.7 KFM75662.1 - 0.00057 19.9 3.6 0.00057 19.9 3.6 2.0 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF679 PF05078.12 KFM75662.1 - 0.23 11.4 3.7 14 5.6 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF679) zf-C3H2C3 PF17122.5 KFM75662.1 - 0.44 10.6 4.7 1.5 8.9 4.7 2.0 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KFM75662.1 - 0.73 10.1 8.8 14 6.0 8.8 3.1 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KFM75662.1 - 0.75 10.0 9.1 2.1 8.5 8.0 2.2 1 1 1 2 2 2 0 RING-variant domain zf-RING_4 PF14570.6 KFM75662.1 - 4.4 7.2 9.6 1.5 8.7 4.3 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KFM75662.1 - 7.4 7.0 7.6 9.1 6.7 5.9 2.1 1 1 1 2 2 2 0 RING-like domain UcrQ PF02939.16 KFM75663.1 - 0.1 12.5 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 UcrQ family G2BR PF18442.1 KFM75664.1 - 1.2e-08 34.4 1.2 1.5e-08 34.1 1.2 1.2 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) DAD PF02109.16 KFM75666.1 - 5.2e-25 87.9 1.8 6.2e-25 87.6 1.8 1.0 1 0 0 1 1 1 1 DAD family C12orf66_like PF09404.10 KFM75667.1 - 2.2e-131 438.7 7.7 5.8e-111 371.4 2.4 2.0 2 0 0 2 2 2 2 KICSTOR complex C12orf66 like adh_short PF00106.25 KFM75668.1 - 2.4e-45 154.4 0.0 3.2e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM75668.1 - 3.4e-32 111.9 0.0 4.7e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM75668.1 - 4.1e-08 33.3 0.0 6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain ERGIC_N PF13850.6 KFM75669.1 - 1.6e-33 114.9 0.2 1.9e-33 114.6 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CST-I PF06002.12 KFM75669.1 - 0.089 12.5 0.1 0.098 12.4 0.1 1.1 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) COPIIcoated_ERV PF07970.12 KFM75670.1 - 2.2e-86 289.3 0.4 2.5e-86 289.1 0.4 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Pkinase PF00069.25 KFM75671.1 - 8.3e-37 127.0 0.0 1.1e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM75671.1 - 1.2e-14 54.2 0.0 1.7e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM75671.1 - 0.024 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFM75671.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_Tnp_Tc3_2 PF01498.18 KFM75672.1 - 1.9e-19 69.7 3.8 4.7e-19 68.4 2.1 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75672.1 - 3.3e-16 59.4 0.0 1.7e-15 57.0 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM75672.1 - 2.8e-07 31.0 4.3 2.9e-07 31.0 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM75672.1 - 0.00029 20.7 0.7 0.0048 16.8 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_29 PF13551.6 KFM75672.1 - 0.00089 19.2 0.3 0.019 15.0 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 KFM75672.1 - 0.0011 18.9 0.3 0.017 15.1 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM75672.1 - 0.0014 18.7 1.2 0.27 11.4 0.0 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75672.1 - 0.019 14.8 1.8 1.1 9.1 0.0 3.1 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 KFM75672.1 - 0.02 15.0 0.6 8 6.6 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 KFM75672.1 - 0.11 12.7 0.1 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 KFM75672.1 - 0.11 12.4 0.2 12 5.8 0.0 3.0 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB MFS_1 PF07690.16 KFM75673.1 - 2.1e-56 191.4 24.6 9e-55 186.0 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM75673.1 - 0.00011 21.2 24.5 0.00047 19.1 24.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter AAA PF00004.29 KFM75674.1 - 3.9e-13 50.0 0.4 7e-13 49.1 0.2 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HTH_IclR PF09339.10 KFM75679.1 - 9.6e-06 25.3 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KFM75679.1 - 0.0017 18.1 0.2 0.0034 17.1 0.2 1.5 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 KFM75679.1 - 0.0031 17.4 0.1 0.0044 16.9 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_29 PF13551.6 KFM75679.1 - 0.011 15.8 0.8 0.018 15.0 0.8 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_31 PF13560.6 KFM75679.1 - 0.031 14.6 2.0 0.16 12.4 1.9 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_AraC PF00165.23 KFM75679.1 - 0.064 13.4 0.1 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_35 PF13693.6 KFM75679.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Insulin PF00049.18 KFM75680.1 - 0.02 15.9 0.0 0.026 15.5 0.0 1.2 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family Cuticle_2 PF08184.11 KFM75681.1 - 0.00048 20.1 0.1 0.00048 20.1 0.1 1.9 2 0 0 2 2 2 1 Cuticle protein 7 isoform family DUF4223 PF13978.6 KFM75681.1 - 0.38 10.7 1.5 4.7 7.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) DUF383 PF04063.14 KFM75683.1 - 3.8e-37 127.8 3.7 7.5e-37 126.8 1.9 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KFM75683.1 - 2.3e-12 46.6 0.0 1.3e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT PF02985.22 KFM75683.1 - 0.011 15.9 0.7 11 6.6 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat RICTOR_V PF14668.6 KFM75683.1 - 0.029 14.6 0.0 21 5.4 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 NUC130_3NT PF08158.12 KFM75683.1 - 0.058 13.7 0.0 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 NUC130/3NT domain PIG-L PF02585.17 KFM75684.1 - 2.2e-07 31.5 0.1 2.8e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase CBF PF03914.17 KFM75686.1 - 4.1e-52 176.6 0.3 1.2e-51 175.2 0.3 1.8 1 0 0 1 1 1 1 CBF/Mak21 family DUF3137 PF11335.8 KFM75686.1 - 0.13 12.2 1.2 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) vATP-synt_E PF01991.18 KFM75687.1 - 0.3 10.5 2.3 2.4 7.5 0.5 2.2 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit UBA_5 PF16577.5 KFM75688.1 - 0.089 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 UBA domain TP53IP5 PF15331.6 KFM75688.1 - 3 7.9 7.4 0.37 10.9 3.6 1.4 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Presenilin PF01080.17 KFM75688.1 - 6.2 5.5 5.2 6.6 5.4 5.2 1.2 1 0 0 1 1 1 0 Presenilin ZZ PF00569.17 KFM75689.1 - 1.6e-11 43.8 9.0 2.4e-11 43.2 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 KFM75689.1 - 1.4e-05 24.9 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 KFM75689.1 - 0.0004 20.6 8.2 0.0004 20.6 8.2 1.9 2 0 0 2 2 2 1 C1 domain DUF3908 PF13048.6 KFM75689.1 - 0.0045 17.2 0.0 0.0088 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3908) DUF3676 PF12429.8 KFM75689.1 - 0.011 15.6 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) PPV_E2_C PF00511.17 KFM75689.1 - 0.016 15.3 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 E2 (early) protein, C terminal zf-UBR PF02207.20 KFM75689.1 - 0.021 15.0 6.9 0.049 13.8 6.9 1.6 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-HIT PF04438.16 KFM75689.1 - 6 6.8 9.0 23 4.9 9.3 1.8 1 1 1 2 2 2 0 HIT zinc finger Amidase PF01425.21 KFM75690.1 - 6.5e-62 210.0 0.1 7.7e-62 209.7 0.1 1.0 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KFM75691.1 - 9.7e-06 24.8 0.0 9.7e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Amidase zf-H2C2_2 PF13465.6 KFM75693.1 - 5.3e-37 124.6 57.2 1.9e-07 31.2 1.4 9.3 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75693.1 - 1.1e-34 116.9 59.1 8.2e-05 22.9 2.0 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75693.1 - 1.1e-29 100.5 54.9 0.0012 19.5 1.9 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75693.1 - 2e-23 82.1 34.9 0.00015 21.9 0.1 8.3 8 0 0 8 8 8 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM75693.1 - 4.7e-20 71.3 43.8 0.00037 20.8 0.5 8.4 8 0 0 8 8 8 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM75693.1 - 3.8e-12 45.9 48.1 0.00019 21.3 0.2 8.7 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM75693.1 - 0.00031 20.6 36.7 2.9 7.9 0.0 8.4 8 0 0 8 8 8 2 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KFM75693.1 - 0.0005 20.5 41.6 0.001 19.4 0.4 7.5 2 1 5 7 7 7 1 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 KFM75693.1 - 0.0029 17.4 17.3 0.4 10.5 1.4 5.5 3 2 3 6 6 6 2 GAGA factor Cript PF10235.9 KFM75693.1 - 0.0037 17.8 24.3 0.024 15.2 0.0 5.3 1 1 4 6 6 6 2 Microtubule-associated protein CRIPT FYVE PF01363.21 KFM75693.1 - 0.0091 16.1 34.7 2.4 8.4 5.4 5.0 3 2 0 4 4 4 2 FYVE zinc finger Zn-ribbon_8 PF09723.10 KFM75693.1 - 0.014 15.5 30.0 0.3 11.3 1.0 6.0 5 1 1 6 6 6 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KFM75693.1 - 0.017 15.4 40.3 8.1 6.8 0.2 7.5 1 1 4 6 6 5 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM75693.1 - 0.043 13.8 21.6 0.7 9.9 0.5 5.4 4 2 0 4 4 4 0 Adenylate kinase, active site lid zf-CHCC PF10276.9 KFM75693.1 - 0.066 13.3 18.1 0.51 10.4 0.0 5.8 6 0 0 6 6 6 0 Zinc-finger domain Thioredoxin_16 PF18569.1 KFM75693.1 - 0.068 13.3 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain zf-C2H2_9 PF16293.5 KFM75693.1 - 0.71 9.8 17.8 22 5.0 0.2 6.9 4 2 4 8 8 8 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_9 PF14369.6 KFM75693.1 - 0.89 9.9 0.0 0.89 9.9 0.0 6.2 7 1 1 8 8 7 0 zinc-ribbon Ribosomal_L28 PF00830.19 KFM75693.1 - 1.2 9.4 18.5 1.1 9.6 0.7 5.6 5 2 0 5 5 5 0 Ribosomal L28 family zinc_ribbon_15 PF17032.5 KFM75693.1 - 1.4 9.7 26.6 6.3 7.6 7.3 4.6 1 1 4 5 5 5 0 zinc-ribbon family zf-C2H2_11 PF16622.5 KFM75693.1 - 3.1 7.6 34.2 3.3 7.6 0.6 7.3 7 0 0 7 7 7 0 zinc-finger C2H2-type Baculo_IE-1 PF05290.11 KFM75693.1 - 9.1 6.2 18.3 0.73 9.8 0.1 4.4 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) RNF220 PF15926.5 KFM75695.1 - 5.8e-16 58.9 7.2 7e-10 39.0 1.0 3.1 1 1 2 3 3 3 2 E3 ubiquitin-protein ligase RNF220 zf-Di19 PF05605.12 KFM75695.1 - 0.0046 17.2 2.1 1.8 8.9 0.1 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DNA_ligase_ZBD PF03119.16 KFM75695.1 - 0.043 13.8 6.4 0.28 11.2 0.2 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-C2H2_9 PF16293.5 KFM75695.1 - 0.055 13.3 2.0 8.7 6.3 0.2 3.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 KFM75695.1 - 0.15 12.2 3.0 7.2 6.8 1.2 3.0 2 0 0 2 2 2 0 Zinc ribbon domain Rad50_zn_hook PF04423.14 KFM75695.1 - 1 9.3 14.5 0.24 11.3 0.8 4.4 5 0 0 5 5 5 0 Rad50 zinc hook motif HTH_Tnp_Tc3_2 PF01498.18 KFM75696.1 - 2.6e-16 59.6 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75696.1 - 1.8e-13 50.5 0.0 2.9e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.18 KFM75697.1 - 1.4e-26 92.1 0.3 3e-26 91.1 0.3 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) Thymidylate_kin PF02223.17 KFM75698.1 - 1.5e-43 148.7 0.0 1.7e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 KFM75698.1 - 0.0011 19.5 0.0 0.002 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFM75698.1 - 0.0056 16.2 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CotJB PF12652.7 KFM75698.1 - 0.055 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 CotJB protein CPT PF07931.12 KFM75698.1 - 0.056 13.3 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein dNK PF01712.19 KFM75698.1 - 0.15 11.9 0.0 2.4 8.0 0.0 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_22 PF13401.6 KFM75698.1 - 0.16 12.3 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KFM75698.1 - 0.2 10.6 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB WD40 PF00400.32 KFM75699.1 - 2.7e-23 81.8 1.7 0.00018 22.2 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM75699.1 - 2.3e-14 53.4 0.0 0.014 15.6 0.0 5.1 3 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFM75699.1 - 0.00029 20.7 0.6 0.15 12.1 0.0 2.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KFM75699.1 - 0.001 17.8 0.0 0.91 8.1 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Arylsulfotran_2 PF14269.6 KFM75699.1 - 0.032 13.6 0.2 0.045 13.1 0.2 1.3 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) Frtz PF11768.8 KFM75699.1 - 0.074 11.4 0.1 6.5 4.9 0.0 2.4 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KFM75699.1 - 0.081 11.9 0.3 6.8 5.6 0.0 2.9 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KFM75699.1 - 0.11 12.1 0.0 2 7.9 0.0 2.4 2 1 1 3 3 3 0 PQQ-like domain DUF4147 PF13660.6 KFM75700.1 - 3.2e-59 200.3 0.4 5.7e-59 199.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 KFM75700.1 - 1.9e-38 131.0 0.6 3.2e-38 130.2 0.6 1.4 1 0 0 1 1 1 1 MOFRL family IFT57 PF10498.9 KFM75701.1 - 0.015 14.3 3.9 0.017 14.1 3.9 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HZS_alpha PF18582.1 KFM75701.1 - 0.088 13.3 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 Hydrazine synthase alpha subunit middle domain DAG1 PF05454.11 KFM75704.1 - 3.9e-75 252.9 1.4 4.1e-59 200.3 1.2 2.2 2 0 0 2 2 2 2 Dystroglycan (Dystrophin-associated glycoprotein 1) a_DG1_N2 PF18424.1 KFM75704.1 - 3.8e-17 62.5 0.0 6.4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Alpha-Dystroglycan N-terminal domain 2 He_PIG PF05345.12 KFM75704.1 - 2.2e-05 24.5 0.0 0.19 11.9 0.0 3.2 2 0 0 2 2 2 2 Putative Ig domain TMEM154 PF15102.6 KFM75704.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 KFM75704.1 - 0.88 9.0 5.5 1.8 8.0 5.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FeoB_associated PF12669.7 KFM75704.1 - 1.1 9.7 2.3 2 8.9 2.3 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein zf-C2H2 PF00096.26 KFM75705.1 - 1.2e-12 47.5 6.0 7.2e-06 26.2 2.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75705.1 - 3.9e-10 39.7 6.7 0.00013 22.5 1.5 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM75705.1 - 1.7e-08 34.5 7.2 6.9e-08 32.6 1.8 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-met PF12874.7 KFM75705.1 - 2.1e-08 34.3 5.4 9.7e-05 22.6 0.7 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type LIM PF00412.22 KFM75705.1 - 4.2e-05 23.7 4.1 0.0027 17.9 4.0 2.1 1 1 1 2 2 2 2 LIM domain zf-C2H2_6 PF13912.6 KFM75705.1 - 0.00031 20.6 9.7 0.062 13.3 0.1 2.8 3 1 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75705.1 - 0.00047 20.4 12.0 0.021 15.1 0.1 2.9 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFM75705.1 - 0.0023 18.2 1.6 0.0026 18.0 1.6 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-LYAR PF08790.11 KFM75705.1 - 0.0059 16.5 3.9 0.91 9.5 0.5 2.5 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-Di19 PF05605.12 KFM75705.1 - 0.0061 16.8 4.7 1.1 9.6 0.6 2.1 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFM75705.1 - 0.011 16.0 1.3 0.13 12.6 0.6 2.1 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_2 PF12756.7 KFM75705.1 - 0.011 16.0 4.8 0.35 11.2 0.5 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Prok-RING_1 PF14446.6 KFM75705.1 - 0.025 14.5 1.7 4.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf_C2H2_ZHX PF18387.1 KFM75705.1 - 0.028 14.1 5.8 0.84 9.3 0.9 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 KFM75705.1 - 0.028 15.1 2.5 0.055 14.1 1.7 1.9 2 1 0 2 2 1 0 Zinc finger C2H2-type, 3 repeats zf-Sec23_Sec24 PF04810.15 KFM75705.1 - 0.04 14.0 3.0 6.3 6.9 0.1 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf_UBZ PF18439.1 KFM75705.1 - 0.073 12.7 0.9 3.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 KFM75705.1 - 0.082 12.7 0.8 0.082 12.7 0.8 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf_ZIC PF18366.1 KFM75705.1 - 0.096 12.8 2.1 0.66 10.1 0.1 2.3 1 1 1 2 2 2 0 Zic proteins zinc finger domain Endonuclease_7 PF02945.15 KFM75705.1 - 0.11 12.4 2.1 0.15 12.0 2.1 1.3 1 1 0 1 1 1 0 Recombination endonuclease VII zf-C2HE PF16278.5 KFM75705.1 - 0.15 12.5 4.9 3.2 8.3 0.5 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger C5HCH PF17982.1 KFM75705.1 - 0.19 11.9 3.3 0.98 9.6 2.9 2.1 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-C2HC_2 PF13913.6 KFM75705.1 - 0.28 11.1 7.3 2.9 7.9 1.0 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-BED PF02892.15 KFM75705.1 - 0.62 10.1 8.6 2.8 8.0 2.2 2.7 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KFM75706.1 - 1.7e-19 69.3 25.0 6.4e-10 39.0 1.0 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75706.1 - 1.7e-16 59.7 26.1 3e-06 27.4 2.4 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75706.1 - 2.4e-13 49.7 23.6 5.2e-05 23.7 2.8 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM75706.1 - 2.8e-06 27.5 20.7 0.0011 19.3 2.0 3.5 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM75706.1 - 1.1e-05 25.3 20.4 0.047 13.7 1.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger GAGA PF09237.11 KFM75706.1 - 0.00031 20.5 1.3 1.6 8.6 0.1 3.1 1 1 2 3 3 3 1 GAGA factor zf-H2C2_5 PF13909.6 KFM75706.1 - 0.00038 20.2 21.5 0.01 15.6 0.1 4.2 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM75706.1 - 0.0016 18.7 18.9 0.1 12.9 2.2 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM75706.1 - 0.0076 16.6 12.1 2 8.8 0.3 3.1 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-FLZ PF04570.14 KFM75706.1 - 0.014 14.9 7.4 0.063 12.8 3.5 2.6 2 1 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 zinc_ribbon_9 PF14369.6 KFM75706.1 - 0.044 14.0 4.4 0.98 9.7 2.5 2.8 2 1 0 2 2 2 0 zinc-ribbon zf-C2H2_11 PF16622.5 KFM75706.1 - 0.07 12.9 19.2 0.76 9.6 1.6 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KFM75706.1 - 0.088 13.3 19.7 0.63 10.5 1.3 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 KFM75706.1 - 0.32 11.0 4.2 0.86 9.6 4.2 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_3rep PF18868.1 KFM75706.1 - 0.34 11.6 8.4 0.24 12.1 0.6 2.6 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Zf_RING PF16744.5 KFM75706.1 - 0.92 9.7 9.0 11 6.2 0.2 3.0 1 1 1 2 2 2 0 KIAA1045 RING finger zf-FCS PF06467.14 KFM75706.1 - 0.99 9.4 11.7 1.2 9.1 5.9 2.6 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-Dof PF02701.15 KFM75706.1 - 1.7 8.9 9.4 6.5 7.0 0.6 3.1 1 1 2 3 3 3 0 Dof domain, zinc finger zf-C2HC_2 PF13913.6 KFM75706.1 - 1.9 8.5 17.4 2.7 8.0 0.7 3.7 3 2 0 3 3 3 0 zinc-finger of a C2HC-type zf-BED PF02892.15 KFM75706.1 - 2 8.5 18.7 8.7 6.5 1.1 3.5 1 1 2 3 3 3 0 BED zinc finger UBZ_FAAP20 PF15750.5 KFM75706.1 - 2.3 8.2 10.9 6.6 6.8 0.3 3.2 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-MYST PF17772.1 KFM75706.1 - 2.4 7.8 12.4 8.2 6.1 0.9 3.1 1 1 2 3 3 3 0 MYST family zinc finger domain C1_4 PF07975.12 KFM75706.1 - 4.8 7.5 12.1 1.4 9.2 3.9 2.4 1 1 2 3 3 3 0 TFIIH C1-like domain Ta0938 PF11494.8 KFM75706.1 - 5.6 7.3 8.2 2.5 8.5 0.7 2.9 1 1 2 3 3 3 0 Ta0938 FYVE PF01363.21 KFM75706.1 - 6.1 7.1 17.8 16 5.7 2.4 2.8 1 1 0 2 2 2 0 FYVE zinc finger zf-C2H2 PF00096.26 KFM75707.1 - 0.0015 18.9 0.2 0.0015 18.9 0.2 1.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM75707.1 - 0.036 13.8 0.1 0.036 13.8 0.1 2.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Cyc-maltodext_N PF09087.11 KFM75707.1 - 0.13 12.5 0.0 0.14 12.5 0.0 1.0 1 0 0 1 1 1 0 Cyclomaltodextrinase, N-terminal zf-C2H2_4 PF13894.6 KFM75707.1 - 0.49 11.4 0.2 0.49 11.4 0.2 2.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM75708.1 - 2.6e-12 46.4 17.3 2.1e-06 27.8 5.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM75708.1 - 3.9e-10 39.7 17.5 9.2e-07 29.0 3.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM75708.1 - 8.3e-09 35.6 15.0 0.00039 21.0 4.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM75708.1 - 2.1e-07 31.1 6.6 0.003 17.9 1.3 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM75708.1 - 5.5e-06 26.0 3.1 0.018 14.8 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM75708.1 - 0.0011 18.7 10.4 0.0042 16.8 1.0 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFM75708.1 - 0.0046 17.3 7.4 0.23 11.8 1.6 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFM75708.1 - 0.016 15.4 11.9 0.068 13.5 2.0 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KFM75708.1 - 0.03 14.4 13.3 0.2 11.7 10.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2HE PF16278.5 KFM75708.1 - 0.045 14.2 13.6 0.9 10.0 5.9 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFM75708.1 - 0.07 13.1 4.6 0.07 13.1 4.6 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM75708.1 - 0.073 13.0 7.1 0.25 11.3 0.4 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GAGA PF09237.11 KFM75708.1 - 0.073 12.9 3.4 1.1 9.1 0.2 2.1 1 1 1 2 2 2 0 GAGA factor DUF4764 PF15961.5 KFM75708.1 - 0.094 11.4 9.7 0.71 8.5 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) DUF2256 PF10013.9 KFM75708.1 - 0.12 12.5 4.3 3.3 7.9 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 KFM75708.1 - 0.22 11.7 8.6 0.36 11.0 8.6 1.4 1 1 0 1 1 1 0 FYVE zinc finger Vps39_2 PF10367.9 KFM75708.1 - 0.38 11.2 5.6 0.59 10.6 0.7 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Transposase_1 PF01359.18 KFM75709.1 - 0.12 12.2 0.3 0.45 10.4 0.1 1.8 1 1 1 2 2 2 0 Transposase (partial DDE domain) zf-C2H2 PF00096.26 KFM75711.1 - 4.6e-05 23.6 24.2 0.006 17.0 0.1 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75711.1 - 0.0068 17.2 30.8 0.018 15.8 0.5 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFM75711.1 - 0.025 14.2 0.1 0.025 14.2 0.1 3.9 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KFM75711.1 - 0.056 13.8 8.5 0.3 11.4 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_Hakai PF18408.1 KFM75711.1 - 3.4 7.5 7.6 0.27 11.0 1.2 2.6 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-H2C2_2 PF13465.6 KFM75711.1 - 7.5 7.2 18.2 6.4 7.4 0.9 5.2 4 2 0 4 4 4 0 Zinc-finger double domain Oxidored_q6 PF01058.22 KFM75713.1 - 6.3e-24 84.3 0.1 7.4e-24 84.0 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HTH_Tnp_Tc3_2 PF01498.18 KFM75715.1 - 4e-32 110.3 13.3 2e-16 60.0 0.6 3.0 3 0 0 3 3 3 2 Transposase DDE_3 PF13358.6 KFM75715.1 - 3.3e-14 52.9 0.0 5.8e-13 48.8 0.0 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75715.1 - 2.2e-07 30.5 3.5 1.3e-06 28.1 0.2 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75715.1 - 0.0011 18.7 2.6 0.014 15.2 0.5 3.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75715.1 - 0.028 14.6 1.2 0.18 12.0 0.5 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM75716.1 - 1.8e-16 60.1 2.2 4.7e-16 58.8 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75716.1 - 3e-15 56.2 0.0 1.7e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease PRP21_like_P PF12230.8 KFM75717.1 - 0.84 9.5 11.7 0.82 9.5 1.0 2.6 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein VPR PF00522.18 KFM75718.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 VPR/VPX protein DDE_1 PF03184.19 KFM75719.1 - 1.9e-13 50.4 0.0 3.5e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM75719.1 - 3.1e-12 46.3 0.4 7.3e-12 45.1 0.4 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM75719.1 - 0.0021 17.8 0.0 0.0069 16.1 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3372 PF11852.8 KFM75719.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) HTH_Tnp_Tc3_2 PF01498.18 KFM75720.1 - 1.9e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75720.1 - 7.6e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_34 PF11312.8 KFM75723.1 - 0.00084 18.7 0.0 0.0037 16.6 0.0 1.8 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF4250 PF14056.6 KFM75723.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Frtz PF11768.8 KFM75724.1 - 3.5e-27 94.9 0.5 4.4e-27 94.6 0.5 1.1 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Frtz PF11768.8 KFM75725.1 - 3.9e-67 226.8 6.6 4.7e-67 226.5 6.6 1.0 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz PI-PLC-X PF00388.19 KFM75726.1 - 4.4e-05 23.1 0.1 7.3e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain APOBEC4 PF18775.1 KFM75726.1 - 0.022 14.9 0.3 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 APOBEC4 DUF3338 PF11819.8 KFM75727.1 - 1.8e-33 115.4 4.2 2.7e-33 114.8 2.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) ZapB PF06005.12 KFM75727.1 - 0.41 11.1 3.4 21 5.6 0.2 2.8 2 0 0 2 2 2 0 Cell division protein ZapB CENP-F_leu_zip PF10473.9 KFM75727.1 - 5.4 7.0 10.3 0.85 9.6 1.6 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cluap1 PF10234.9 KFM75727.1 - 5.7 6.2 11.6 0.24 10.8 3.5 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 HTH_Tnp_Tc5 PF03221.16 KFM75728.1 - 8.6e-12 44.9 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF5355 PF17306.2 KFM75728.1 - 0.01 14.9 0.9 0.012 14.6 0.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5355) Abhydrolase_2 PF02230.16 KFM75729.1 - 1.6e-74 250.4 0.0 1.8e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KFM75729.1 - 6.6e-08 33.4 0.1 7.4e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM75729.1 - 1.8e-06 27.4 0.4 0.035 13.4 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KFM75729.1 - 2.1e-06 27.6 0.0 8.9e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KFM75729.1 - 2.5e-06 27.2 0.0 3.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KFM75729.1 - 3e-05 24.0 0.1 0.00065 19.6 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KFM75729.1 - 0.00022 21.0 1.1 1.1 8.9 0.2 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold DUF2974 PF11187.8 KFM75729.1 - 0.0013 18.3 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 KFM75729.1 - 0.0013 18.2 0.3 0.086 12.3 0.0 2.4 2 1 1 3 3 3 1 Prolyl oligopeptidase family Cutinase PF01083.22 KFM75729.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Esterase PF00756.20 KFM75729.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.10 KFM75729.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein AXE1 PF05448.12 KFM75729.1 - 0.18 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) zf-Di19 PF05605.12 KFM75730.1 - 1e-05 25.8 9.1 9.4e-05 22.6 2.6 3.3 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding UVR PF02151.19 KFM75730.1 - 0.00038 20.1 3.3 0.18 11.6 0.1 3.0 2 0 0 2 2 2 2 UvrB/uvrC motif Prok-RING_4 PF14447.6 KFM75730.1 - 0.024 14.5 10.8 0.32 10.9 0.4 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 PRP21_like_P PF12230.8 KFM75730.1 - 0.027 14.3 7.1 0.23 11.3 2.9 3.0 2 1 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Toxin_trans PF07952.12 KFM75730.1 - 0.1 11.7 5.3 0.034 13.2 1.1 2.2 2 1 0 2 2 2 0 Clostridium neurotoxin, Translocation domain DUF4884 PF16225.5 KFM75730.1 - 0.16 12.1 0.2 0.38 10.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) Sgf11 PF08209.11 KFM75730.1 - 0.64 9.6 3.0 39 3.9 0.0 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-ribbon_3 PF13248.6 KFM75730.1 - 6.5 6.3 7.4 5.7 6.5 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Neur_chan_LBD PF02931.23 KFM75732.1 - 6.7e-48 163.0 1.5 8e-48 162.7 1.5 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF4728 PF15860.5 KFM75733.1 - 4.2e-06 27.3 10.1 6.6e-06 26.7 10.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4728) DUF1345 PF07077.11 KFM75733.1 - 0.016 14.9 8.4 0.048 13.4 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF4199 PF13858.6 KFM75733.1 - 0.05 14.0 8.9 0.3 11.5 8.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) PDR_CDR PF06422.12 KFM75733.1 - 0.11 12.4 3.3 0.43 10.5 0.1 2.3 2 0 0 2 2 2 0 CDR ABC transporter TssN PF17555.2 KFM75733.1 - 0.29 10.5 10.1 0.36 10.2 10.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DHHC PF01529.20 KFM75733.1 - 0.34 11.0 7.1 0.59 10.3 7.1 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase PIG-Y PF15159.6 KFM75733.1 - 1.4 9.9 11.1 1.1 10.2 6.6 2.3 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y FKBP_C PF00254.28 KFM75734.1 - 8.5e-16 58.1 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KFM75734.1 - 4.4e-13 48.4 1.6 0.002 17.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM75734.1 - 4.2e-12 45.2 0.4 0.0014 18.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM75734.1 - 8.8e-08 31.8 1.2 0.0061 16.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM75734.1 - 6.8e-07 28.9 2.5 0.13 12.0 0.1 3.8 2 1 2 4 4 4 3 TPR repeat TPR_16 PF13432.6 KFM75734.1 - 8.1e-07 29.6 0.1 1.3e-05 25.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM75734.1 - 3.2e-06 27.2 0.0 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM75734.1 - 1e-05 25.9 0.4 4.4e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 KFM75734.1 - 2.4e-05 23.5 4.4 3.3e-05 23.0 3.5 1.5 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 KFM75734.1 - 7.4e-05 23.0 0.1 5.8 7.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM75734.1 - 0.00023 21.7 0.0 0.12 13.2 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM75734.1 - 0.0006 19.8 0.8 0.0017 18.3 0.1 2.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat NRBF2_MIT PF17169.4 KFM75734.1 - 0.00097 19.3 5.6 0.08 13.2 1.6 2.9 3 0 0 3 3 3 2 MIT domain of nuclear receptor-binding factor 2 ANAPC3 PF12895.7 KFM75734.1 - 0.0022 18.2 0.5 0.0054 16.9 0.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFM75734.1 - 0.0059 16.9 2.9 0.035 14.5 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 KFM75734.1 - 0.01 15.9 0.0 0.053 13.6 0.0 2.3 1 1 0 1 1 1 0 BDBT FKBP like N-terminal DUF3856 PF12968.7 KFM75734.1 - 0.015 15.3 0.2 0.25 11.4 0.2 2.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Pex26 PF07163.12 KFM75734.1 - 0.024 14.0 1.6 0.043 13.1 1.6 1.4 1 0 0 1 1 1 0 Pex26 protein TPR_7 PF13176.6 KFM75734.1 - 0.027 14.5 0.7 39 4.6 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1940 PF09155.10 KFM75734.1 - 0.068 13.3 1.1 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) HMG_box PF00505.19 KFM75735.1 - 3.2e-22 78.7 1.5 3.2e-22 78.7 1.5 2.8 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM75735.1 - 1e-13 51.6 1.4 1e-13 51.6 1.4 3.2 3 1 0 3 3 3 1 HMG-box domain PPP4R2 PF09184.11 KFM75735.1 - 0.42 10.1 17.1 0.52 9.9 17.1 1.2 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 KFM75735.1 - 5.9 6.5 25.8 1.7 8.3 22.9 1.6 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein VWA_2 PF13519.6 KFM75738.1 - 2.7e-15 56.9 0.0 4.4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFM75738.1 - 0.0084 16.4 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain BTB PF00651.31 KFM75739.1 - 2.2e-38 130.9 0.3 8.6e-25 87.1 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain BTB_3 PF16017.5 KFM75739.1 - 0.00015 21.9 0.3 0.0086 16.2 0.0 3.2 3 0 0 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFM75739.1 - 0.017 15.2 2.9 0.081 13.0 0.4 2.9 3 0 0 3 3 3 0 BTB And C-terminal Kelch MATH PF00917.26 KFM75739.1 - 0.033 14.4 0.0 0.033 14.4 0.0 2.9 4 1 0 4 4 4 0 MATH domain BTB PF00651.31 KFM75740.1 - 2.2e-29 101.9 2.1 2.4e-17 63.1 0.7 2.4 2 0 0 2 2 2 2 BTB/POZ domain Phage_tail_T PF06223.12 KFM75740.1 - 0.063 13.8 0.0 1.1 9.8 0.0 2.9 2 1 1 3 3 3 0 Minor tail protein T MATH PF00917.26 KFM75740.1 - 0.073 13.2 0.6 0.39 10.9 0.1 2.3 2 0 0 2 2 2 0 MATH domain Peptidase_M13_N PF05649.13 KFM75741.1 - 7.3e-108 361.6 0.0 1e-107 361.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM75741.1 - 1.9e-67 226.8 0.0 4.7e-67 225.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 Nexin_C PF08628.12 KFM75742.1 - 7.6e-32 110.2 0.0 1.5e-31 109.2 0.0 1.5 2 0 0 2 2 2 1 Sorting nexin C terminal EMC3_TMCO1 PF01956.16 KFM75742.1 - 0.029 14.1 0.1 0.034 13.9 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF1029 PF06269.12 KFM75743.1 - 0.011 15.8 0.9 0.011 15.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) RGS PF00615.19 KFM75744.1 - 3.1e-10 40.3 1.0 4.9e-10 39.7 1.0 1.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF5460 PF17544.2 KFM75744.1 - 0.0078 15.3 0.0 0.15 11.1 0.0 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5460) PXA PF02194.15 KFM75745.1 - 2.5e-30 105.8 1.2 3.2e-30 105.5 1.2 1.1 1 0 0 1 1 1 1 PXA domain Pkinase_Tyr PF07714.17 KFM75750.1 - 6.9e-22 78.0 0.0 8.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM75750.1 - 6.8e-21 74.8 0.0 9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Band_7 PF01145.25 KFM75751.1 - 1.2e-27 97.1 0.5 1.6e-27 96.6 0.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family FliG_N PF14842.6 KFM75751.1 - 0.019 15.5 3.1 0.18 12.4 0.9 2.4 2 0 0 2 2 2 0 FliG N-terminal domain Med2 PF11214.8 KFM75751.1 - 0.021 15.0 0.8 0.036 14.2 0.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 HxlR PF01638.17 KFM75751.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Pkinase_Tyr PF07714.17 KFM75752.1 - 7.7e-37 127.0 0.1 1.2e-36 126.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM75752.1 - 6.4e-36 124.1 0.0 1.1e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFM75752.1 - 1.9e-12 46.4 0.2 4.5e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFM75752.1 - 5.4e-07 30.6 13.5 1.6e-06 29.1 13.5 1.9 1 0 0 1 1 1 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFM75752.1 - 3.8e-05 22.7 0.0 6.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase TMEM154 PF15102.6 KFM75752.1 - 0.0003 20.7 0.1 0.00058 19.8 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family PspB PF06667.12 KFM75752.1 - 0.041 13.9 2.6 0.16 12.0 0.2 2.3 2 0 0 2 2 2 0 Phage shock protein B FTA2 PF13095.6 KFM75752.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Insulin_TMD PF17870.1 KFM75752.1 - 0.26 11.4 2.9 0.32 11.1 1.5 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment BAMBI PF06211.12 KFM75752.1 - 0.3 11.3 7.1 0.71 10.2 7.1 1.5 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain DUF648 PF04890.13 KFM75752.1 - 1.2 8.9 2.9 2.1 8.0 2.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF648) PHO4 PF01384.20 KFM75753.1 - 2e-132 441.4 13.7 2.4e-132 441.1 13.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family UPF0020 PF01170.18 KFM75754.1 - 1.9e-12 47.3 0.0 4.1e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KFM75754.1 - 4.2e-07 29.9 0.2 8e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 KFM75754.1 - 3.2e-05 23.3 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 KFM75754.1 - 0.00046 20.8 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFM75754.1 - 0.0034 16.8 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFM75754.1 - 0.011 16.4 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM75754.1 - 0.024 14.3 0.1 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 DUF3437 PF11919.8 KFM75755.1 - 0.034 14.1 4.0 4.1 7.4 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) CLCA PF08434.11 KFM75756.1 - 1.1e-22 80.7 0.0 2.4e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal YtkA PF13115.6 KFM75756.1 - 0.058 14.0 0.0 0.25 12.0 0.0 2.1 1 1 0 1 1 1 0 YtkA-like Orf78 PF06024.12 KFM75756.1 - 0.18 12.1 0.7 0.42 10.9 0.1 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Tetraspanin PF00335.20 KFM75756.1 - 0.27 10.9 1.4 18 5.0 0.0 3.0 3 0 0 3 3 3 0 Tetraspanin family Adeno_E3_CR2 PF02439.15 KFM75756.1 - 3.8 7.3 5.3 1.5 8.6 0.7 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 ECH_1 PF00378.20 KFM75757.1 - 1.1e-91 306.6 0.2 1.3e-91 306.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM75757.1 - 1.1e-35 123.7 0.5 3.6e-32 112.2 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFM75757.1 - 0.0022 18.0 0.1 0.4 10.6 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 Cobalamin_bind PF01122.19 KFM75758.1 - 1.5e-19 70.1 2.9 4.3e-19 68.6 2.9 1.6 1 1 0 1 1 1 1 Eukaryotic cobalamin-binding protein Ldl_recept_a PF00057.18 KFM75758.1 - 5.5e-17 61.7 28.4 9.8e-10 38.5 10.6 2.8 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A DUF3346 PF11826.8 KFM75758.1 - 0.013 15.3 0.5 0.028 14.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3346) SQHop_cyclase_C PF13243.6 KFM75758.1 - 0.091 11.8 0.1 0.48 9.5 0.0 2.1 3 0 0 3 3 3 0 Squalene-hopene cyclase C-terminal domain DDE_3 PF13358.6 KFM75759.1 - 4.9e-06 26.4 0.1 2.7e-05 24.0 0.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease PIF1 PF05970.14 KFM75760.1 - 3e-50 171.4 0.3 1e-49 169.6 0.0 1.8 2 0 0 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.6 KFM75760.1 - 9.6e-29 100.9 2.0 1e-28 100.9 0.2 2.0 3 0 0 3 3 3 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 KFM75760.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain LSM PF01423.22 KFM75761.1 - 3.6e-15 55.4 0.3 4.6e-15 55.0 0.3 1.1 1 0 0 1 1 1 1 LSM domain DDE_3 PF13358.6 KFM75762.1 - 8e-05 22.4 0.0 8.1e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Exo_endo_phos PF03372.23 KFM75763.1 - 0.00016 21.2 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rad17 PF03215.15 KFM75764.1 - 3.1e-06 27.2 0.0 3.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain OATP PF03137.20 KFM75765.1 - 1.3e-146 489.1 14.6 2.5e-146 488.2 14.6 1.5 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFM75765.1 - 1.7e-16 60.1 25.3 1.8e-16 60.0 22.2 2.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFM75765.1 - 4.4e-08 33.1 11.2 1.4e-07 31.5 11.2 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain PUCC PF03209.15 KFM75765.1 - 0.01 14.9 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 PUCC protein OATP PF03137.20 KFM75766.1 - 9.4e-158 525.9 10.6 1.4e-157 525.3 10.6 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFM75766.1 - 2.5e-20 72.7 17.6 3.2e-18 65.8 15.6 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.15 KFM75766.1 - 5.2e-08 32.9 10.7 1.2e-07 31.7 10.7 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain ATG22 PF11700.8 KFM75766.1 - 0.02 13.5 0.2 0.06 12.0 0.0 1.8 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Sdh_cyt PF01127.22 KFM75766.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.4 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Kazal_1 PF00050.21 KFM75766.1 - 0.62 10.1 10.4 1.3 9.1 10.4 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain HTH_Tnp_Tc3_2 PF01498.18 KFM75767.1 - 2.8e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75767.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75767.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75767.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75767.1 - 1.9 9.2 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain OATP PF03137.20 KFM75768.1 - 2.6e-160 534.3 18.7 3.2e-160 534.0 18.7 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFM75768.1 - 6e-24 84.6 17.7 6.7e-20 71.3 6.0 3.1 3 0 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFM75768.1 - 1.9e-06 27.9 3.5 5.3e-06 26.5 3.5 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain LETM1 PF07766.13 KFM75768.1 - 0.13 11.6 0.3 0.2 11.0 0.3 1.2 1 0 0 1 1 1 0 LETM1-like protein Kazal_1 PF00050.21 KFM75768.1 - 0.15 12.1 3.0 0.37 10.8 3.0 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Phage_holin_3_6 PF07332.11 KFM75768.1 - 0.21 11.7 0.6 3 7.9 0.0 2.9 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Wzy_C PF04932.15 KFM75768.1 - 3.9 7.1 9.2 48 3.5 2.3 4.2 3 2 0 3 3 3 0 O-Antigen ligase RAI1 PF08652.11 KFM75770.1 - 0.026 14.7 0.6 0.097 12.9 0.0 2.1 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease PolyA_pol PF01743.20 KFM75771.1 - 1.6e-34 119.0 1.2 2.2e-34 118.6 1.2 1.2 1 0 0 1 1 1 1 Poly A polymerase head domain TetR_N PF00440.23 KFM75771.1 - 0.023 14.5 0.2 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Aldose_epim PF01263.20 KFM75775.1 - 2.5e-92 309.4 0.5 2.9e-92 309.2 0.5 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase WD40 PF00400.32 KFM75777.1 - 3.4e-38 129.0 20.9 1.1e-05 26.1 0.2 11.8 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM75777.1 - 1e-15 57.8 0.9 0.00097 19.4 0.0 7.9 6 2 3 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 KFM75777.1 - 0.0023 17.5 0.5 0.53 9.8 0.0 3.3 2 1 0 3 3 3 1 Hermansky-Pudlak syndrome 3 LssY_C PF14067.6 KFM75777.1 - 0.14 11.6 0.4 12 5.3 0.1 3.5 3 0 0 3 3 3 0 LssY C-terminus Tap-RNA_bind PF09162.10 KFM75778.1 - 1.6e-29 101.6 0.0 3.8e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Tap, RNA-binding LRR_4 PF12799.7 KFM75778.1 - 3.2e-08 33.7 11.7 5.7e-06 26.6 2.8 2.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM75778.1 - 0.00085 19.0 4.3 0.0029 17.3 4.3 1.9 1 1 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 KFM75778.1 - 0.002 17.6 0.6 0.0036 16.8 0.6 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KFM75778.1 - 1.5 9.0 6.6 7.1 7.0 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeat TAP_C PF03943.13 KFM75779.1 - 1.4e-21 75.9 0.0 2.2e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 KFM75779.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain NTF2 PF02136.20 KFM75779.1 - 0.011 16.3 0.2 0.018 15.6 0.2 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain IRK_N PF08466.10 KFM75780.1 - 0.067 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Inward rectifier potassium channel N-terminal Spaetzle PF16077.5 KFM75782.1 - 2.5e-25 88.9 0.1 3.4e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Spaetzle Astacin PF01400.24 KFM75783.1 - 2.2e-54 184.0 0.0 2.5e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 KFM75784.1 - 4.7e-62 209.0 0.0 5.9e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM75784.1 - 0.26 11.1 0.9 1.1 9.0 0.9 1.9 1 1 0 1 1 1 0 Matrixin MBOAT PF03062.19 KFM75786.1 - 1.6e-20 73.7 25.3 4.7e-20 72.2 25.2 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF373 PF04123.13 KFM75786.1 - 9.2 5.6 6.4 18 4.7 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) I-set PF07679.16 KFM75787.1 - 2.7e-08 33.8 0.0 3.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM75787.1 - 3.6e-05 23.9 0.0 3.9e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM75787.1 - 5.4e-05 23.7 0.0 6.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM75787.1 - 0.00051 20.3 0.0 0.00054 20.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM75787.1 - 0.00065 19.8 0.1 0.0012 19.0 0.0 1.4 1 1 1 2 2 2 1 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM75787.1 - 0.0036 17.7 0.0 0.0037 17.6 0.0 1.1 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM75787.1 - 0.0037 17.5 0.0 0.0053 17.0 0.0 1.3 1 1 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain MJ1316 PF04457.12 KFM75787.1 - 0.039 14.7 0.6 0.052 14.3 0.6 1.3 1 0 0 1 1 1 0 MJ1316 RNA cyclic group end recognition domain Ig_6 PF18452.1 KFM75787.1 - 0.064 12.8 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM75788.1 - 2.9e-16 59.5 3.3 3.9e-16 59.1 2.2 1.8 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM75788.1 - 2e-07 30.6 0.2 5.2e-07 29.3 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75788.1 - 0.0019 18.0 0.6 0.0055 16.5 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75788.1 - 0.021 14.9 0.4 0.066 13.3 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM75788.1 - 0.74 10.5 15.3 0.083 13.5 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain CN_hydrolase PF00795.22 KFM75790.1 - 3.4e-46 157.7 0.2 4.5e-46 157.3 0.2 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF282 PF03380.14 KFM75791.1 - 0.036 14.0 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 Snf7 PF03357.21 KFM75792.1 - 1.2e-20 73.8 9.7 1.2e-20 73.8 9.7 1.4 2 0 0 2 2 2 1 Snf7 zf-H2C2_2 PF13465.6 KFM75793.1 - 3.3e-86 280.2 91.2 1.1e-09 38.2 0.9 12.0 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75793.1 - 3.7e-58 190.9 132.1 9.4e-07 29.0 2.0 12.1 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75793.1 - 3.4e-34 114.6 117.6 0.002 18.8 2.4 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM75793.1 - 3.7e-19 68.2 90.4 0.00028 20.8 0.7 12.9 12 1 0 12 12 12 9 C2H2-type zinc finger ADK_lid PF05191.14 KFM75793.1 - 2.3e-08 33.8 50.4 0.00051 20.0 1.2 8.3 3 1 8 11 11 11 8 Adenylate kinase, active site lid zf-met PF12874.7 KFM75793.1 - 1.5e-06 28.4 96.5 0.016 15.6 1.3 11.4 11 0 0 11 11 11 6 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFM75793.1 - 1.8e-06 27.4 69.5 0.36 10.4 0.1 12.2 12 0 0 12 12 12 6 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KFM75793.1 - 2.2e-05 25.1 55.2 0.17 12.6 1.2 6.4 1 1 4 6 6 6 4 zinc-ribbon family OSTMP1 PF09777.9 KFM75793.1 - 0.00065 19.2 38.2 0.21 11.0 15.5 4.0 1 1 0 2 2 2 2 Osteopetrosis-associated transmembrane protein 1 precursor zf-C2HC_2 PF13913.6 KFM75793.1 - 0.0037 17.1 58.1 0.75 9.8 0.1 12.1 12 0 0 12 12 12 3 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 KFM75793.1 - 0.0047 17.0 48.7 0.33 11.1 1.4 7.9 2 2 7 9 9 9 6 Zinc ribbon domain XPA_N PF01286.18 KFM75793.1 - 0.0048 16.9 55.0 8.5 6.5 0.1 12.0 12 0 0 12 12 12 1 XPA protein N-terminal SKA2 PF16740.5 KFM75793.1 - 0.005 16.6 0.1 25 4.7 0.0 4.6 2 2 4 6 6 6 0 Spindle and kinetochore-associated protein 2 zf-C2H2_jaz PF12171.8 KFM75793.1 - 0.011 16.0 84.4 0.22 11.8 0.5 11.7 10 1 2 12 12 12 0 Zinc-finger double-stranded RNA-binding PHD PF00628.29 KFM75793.1 - 0.023 14.6 7.4 0.023 14.6 7.4 8.1 3 2 4 7 7 6 0 PHD-finger GAGA PF09237.11 KFM75793.1 - 0.042 13.7 26.7 1.2 9.0 0.2 6.1 4 3 2 6 6 6 0 GAGA factor Baculo_IE-1 PF05290.11 KFM75793.1 - 0.44 10.5 38.3 3 7.8 10.3 6.2 1 1 2 4 4 4 0 Baculovirus immediate-early protein (IE-0) zf-RRPl_C4 PF17026.5 KFM75793.1 - 0.76 9.9 53.6 0.59 10.3 5.6 5.1 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2 PF00096.26 KFM75794.1 - 7.7e-22 76.5 50.2 6.5e-06 26.3 3.3 6.1 7 0 0 7 7 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM75794.1 - 2.7e-21 75.0 36.0 1.8e-05 25.0 0.2 6.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM75794.1 - 8.4e-17 60.4 43.1 0.0015 19.2 1.9 6.2 7 0 0 7 7 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM75794.1 - 6.1e-10 38.8 34.0 0.00098 19.1 0.8 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75794.1 - 5.9e-07 29.6 23.2 0.077 13.3 0.1 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM75794.1 - 4e-05 23.9 26.1 0.07 13.5 0.2 5.0 5 0 0 5 5 5 3 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KFM75794.1 - 4.4e-05 23.5 19.4 0.042 14.0 3.4 3.8 3 0 0 3 3 3 2 Zinc ribbon domain C1_4 PF07975.12 KFM75794.1 - 0.00013 22.2 20.4 0.13 12.5 2.3 3.5 1 1 1 3 3 3 2 TFIIH C1-like domain zf-C2HC_2 PF13913.6 KFM75794.1 - 0.011 15.6 1.3 0.011 15.6 1.3 4.5 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 KFM75794.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-AN1 PF01428.16 KFM75794.1 - 0.021 15.0 30.0 0.09 13.0 0.9 6.0 6 0 0 6 6 5 0 AN1-like Zinc finger XPA_N PF01286.18 KFM75794.1 - 0.021 14.8 15.3 1.1 9.3 0.7 5.1 5 0 0 5 5 5 0 XPA protein N-terminal GAGA PF09237.11 KFM75794.1 - 0.039 13.7 0.5 0.039 13.7 0.5 4.6 2 1 3 5 5 4 0 GAGA factor zf-C2HE PF16278.5 KFM75794.1 - 0.043 14.3 1.4 0.043 14.3 1.4 4.6 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DZR PF12773.7 KFM75794.1 - 0.09 12.8 16.7 3.7e+02 1.3 16.7 3.0 1 1 0 1 1 1 0 Double zinc ribbon TRAF6_Z2 PF18048.1 KFM75794.1 - 0.68 10.1 14.1 0.22 11.7 0.9 4.2 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 FYVE PF01363.21 KFM75794.1 - 0.91 9.7 26.0 0.5 10.5 4.6 3.4 1 1 2 3 3 3 0 FYVE zinc finger YhfH PF14149.6 KFM75794.1 - 1.1 9.3 8.8 23 5.1 0.0 3.5 3 0 0 3 3 3 0 YhfH-like protein CpXC PF14353.6 KFM75794.1 - 1.4 9.0 15.7 5.6 7.0 1.0 4.3 1 1 3 4 4 4 0 CpXC protein zinc_ribbon_15 PF17032.5 KFM75794.1 - 1.8 9.4 15.7 18 6.2 6.0 3.1 1 1 3 4 4 4 0 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM75794.1 - 3.1 7.7 6.2 3.5 7.6 0.1 3.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_9 PF14369.6 KFM75794.1 - 3.6 7.9 14.9 29 5.0 0.1 4.7 5 0 0 5 5 4 0 zinc-ribbon zinc-ribbons_6 PF07191.12 KFM75794.1 - 4.6 7.3 18.1 4.4 7.4 1.6 3.7 2 1 1 3 3 3 0 zinc-ribbons zf-H2C2_5 PF13909.6 KFM75794.1 - 4.6 7.1 15.1 3.5 7.4 1.7 4.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Prok-RING_1 PF14446.6 KFM75794.1 - 4.9 7.2 17.8 3.9 7.5 2.6 4.7 4 1 0 4 4 4 0 Prokaryotic RING finger family 1 DUF3268 PF11672.8 KFM75794.1 - 5.3 7.4 8.7 8.7 6.7 0.4 2.6 2 1 1 3 3 3 0 zinc-finger-containing domain DUF2256 PF10013.9 KFM75794.1 - 6.6 6.9 18.5 0.96 9.6 0.1 4.7 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.19 KFM75794.1 - 8.2 6.5 13.5 0.97 9.5 1.6 2.9 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 KFM75794.1 - 9.9 6.2 20.3 0.084 12.9 0.9 4.5 3 2 2 5 5 5 0 Adenylate kinase, active site lid THAP PF05485.12 KFM75795.1 - 4e-16 59.7 3.2 7e-16 58.9 3.2 1.4 1 0 0 1 1 1 1 THAP domain RT_RNaseH_2 PF17919.1 KFM75796.1 - 8.3e-40 134.9 0.0 1.4e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM75796.1 - 2.7e-37 127.3 0.0 4.1e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_3 PF13358.6 KFM75797.1 - 1.4e-10 41.1 0.0 1.6e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75798.1 - 2.6e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75798.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-TRM13_CCCH PF11722.8 KFM75798.1 - 0.12 12.2 0.2 5.7 6.8 0.0 2.5 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein LLGL PF08366.13 KFM75799.1 - 1.8e-28 98.9 0.0 3.1e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 LLGL2 WD40 PF00400.32 KFM75799.1 - 0.004 18.0 0.8 8.3 7.5 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Lgl_C PF08596.10 KFM75800.1 - 2.7e-05 23.1 0.0 0.00036 19.3 0.0 2.0 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal Synaptobrevin PF00957.21 KFM75800.1 - 0.077 12.8 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Synaptobrevin Rsd_AlgQ PF04353.13 KFM75800.1 - 0.11 12.5 0.2 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Inhibitor_I69 PF13734.6 KFM75801.1 - 0.055 13.9 5.9 8.8 6.8 0.0 5.0 4 2 1 5 5 5 0 Spi protease inhibitor p450 PF00067.22 KFM75802.1 - 0.057 12.2 0.1 0.061 12.1 0.1 1.0 1 0 0 1 1 1 0 Cytochrome P450 p450 PF00067.22 KFM75803.1 - 2.6e-16 59.4 1.1 2.9e-16 59.3 1.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 N6_Mtase PF02384.16 KFM75803.1 - 0.013 14.8 0.1 0.014 14.6 0.1 1.0 1 0 0 1 1 1 0 N-6 DNA Methylase Rap1a PF18602.1 KFM75803.1 - 0.047 14.0 0.1 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 Rap1a immunity proteins p450 PF00067.22 KFM75804.1 - 1e-17 64.1 0.0 1.1e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S25 PF03297.15 KFM75805.1 - 1.5e-44 150.3 6.9 2e-44 149.9 6.9 1.2 1 0 0 1 1 1 1 S25 ribosomal protein Fe_dep_repress PF01325.19 KFM75805.1 - 0.002 18.3 0.2 0.004 17.3 0.2 1.6 1 1 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 KFM75805.1 - 0.016 15.1 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 MarR family BioT2 PF15368.6 KFM75805.1 - 0.018 15.0 1.3 0.062 13.2 1.3 1.8 1 1 0 1 1 1 0 Spermatogenesis family BioT2 TrmB PF01978.19 KFM75805.1 - 0.039 13.8 0.7 0.072 13.0 0.4 1.6 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB zf-H2C2_2 PF13465.6 KFM75806.1 - 6.5e-49 162.3 65.3 2.3e-08 34.1 0.2 8.7 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM75806.1 - 1e-28 97.5 69.1 6.2e-05 23.5 0.8 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM75806.1 - 2.8e-28 96.8 79.0 4e-06 27.0 0.6 7.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-met PF12874.7 KFM75806.1 - 1.1e-11 44.7 60.3 0.011 16.1 0.3 7.2 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM75806.1 - 1.2e-11 44.2 55.2 4.9e-05 23.2 0.5 7.8 7 1 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM75806.1 - 7.3e-08 32.0 52.1 3.5e-05 23.5 2.5 7.9 8 0 0 8 8 7 3 C2H2-type zinc-finger domain BolA PF01722.18 KFM75806.1 - 2e-07 31.2 10.7 0.025 14.8 0.1 5.2 1 1 3 4 4 4 2 BolA-like protein zf-C2H2_jaz PF12171.8 KFM75806.1 - 2.9e-06 27.4 51.2 0.02 15.2 1.4 6.9 6 1 1 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM75806.1 - 0.12 12.7 50.5 0.62 10.4 1.3 6.5 1 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM75806.1 - 1.2 9.2 36.3 3.3 7.7 0.2 7.0 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFM75806.1 - 3.8 7.3 41.7 0.72 9.7 1.0 5.9 7 0 0 7 7 7 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFM75806.1 - 6.2 7.6 29.3 3.3 8.5 1.0 4.0 2 2 2 4 4 4 0 zinc-ribbon family Zf_RING PF16744.5 KFM75806.1 - 6.2 7.0 33.9 18 5.5 1.1 6.5 1 1 6 7 7 7 0 KIAA1045 RING finger HTH_Tnp_Tc3_2 PF01498.18 KFM75807.1 - 4.4e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75807.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75807.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75807.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75807.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ig_2 PF13895.6 KFM75808.1 - 0.00056 20.2 0.0 0.00073 19.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM75808.1 - 0.013 16.1 0.0 0.015 15.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFM75808.1 - 0.018 15.2 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain zf-H2C2_2 PF13465.6 KFM75809.1 - 4.7e-81 263.9 95.4 1.3e-07 31.7 1.9 14.1 14 0 0 14 14 14 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75809.1 - 1.1e-57 189.4 127.7 3.2e-06 27.3 0.7 14.1 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75809.1 - 5e-41 135.8 119.2 0.00079 20.1 1.0 14.2 14 0 0 14 14 14 13 C2H2-type zinc finger zf-met PF12874.7 KFM75809.1 - 2.4e-35 119.9 117.0 3.8e-05 23.9 0.8 14.3 13 1 1 14 14 14 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM75809.1 - 2.2e-17 62.8 89.9 0.027 14.7 1.7 14.2 13 1 1 14 14 14 10 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM75809.1 - 2.4e-17 62.3 59.8 0.0053 16.5 0.3 12.7 12 0 0 12 12 12 9 C2H2-type zinc-finger domain BolA PF01722.18 KFM75809.1 - 1.7e-11 44.2 27.4 0.13 12.6 0.2 8.0 1 1 6 7 7 7 6 BolA-like protein zf-C2H2_6 PF13912.6 KFM75809.1 - 2.1e-08 34.0 103.7 0.8 9.8 1.3 14.7 14 0 0 14 14 14 10 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM75809.1 - 4.8e-05 23.0 9.1 0.0003 20.5 2.2 11.9 13 0 0 13 13 12 4 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM75809.1 - 0.00031 20.6 67.1 1.1 9.2 0.4 12.3 14 0 0 14 14 13 7 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM75809.1 - 0.0012 18.9 70.5 5.7 7.1 0.6 13.1 12 1 1 13 13 13 2 DBF zinc finger zf-C2H2_9 PF16293.5 KFM75809.1 - 0.0045 16.8 66.6 2.6 7.9 0.4 12.4 3 2 10 13 13 13 3 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM75809.1 - 0.0073 16.4 72.4 2.6 8.2 12.6 6.2 1 1 5 6 6 6 3 Putative ribonucleoprotein zinc-finger pf C4 type DUF952 PF06108.12 KFM75809.1 - 0.0084 16.1 5.8 4.1 7.5 0.0 5.5 4 3 2 7 7 7 1 Protein of unknown function (DUF952) zf-Sec23_Sec24 PF04810.15 KFM75809.1 - 0.027 14.5 56.0 8.3 6.6 1.3 12.1 7 3 6 13 13 13 0 Sec23/Sec24 zinc finger Tox-HNH-HHH PF15637.6 KFM75809.1 - 0.033 14.3 4.2 16 5.7 0.1 4.0 2 1 2 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif FYVE PF01363.21 KFM75809.1 - 0.12 12.5 86.0 0.31 11.2 11.1 7.9 1 1 4 7 7 7 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM75809.1 - 2.1 9.2 68.3 0.83 10.5 2.9 7.4 2 1 8 10 10 10 0 zinc-ribbon family C1_1 PF00130.22 KFM75809.1 - 2.3 8.2 90.5 0.75 9.7 7.6 10.3 2 1 8 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.6 KFM75810.1 - 5.8e-05 23.3 12.4 0.022 15.2 0.9 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFM75810.1 - 0.015 15.3 0.1 0.015 15.3 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM75810.1 - 0.023 15.2 0.7 0.023 15.2 0.7 2.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75810.1 - 0.22 12.4 0.2 0.22 12.4 0.2 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger DDE_3 PF13358.6 KFM75811.1 - 4.8e-16 58.8 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75811.1 - 7.7e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM75811.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM75811.1 - 0.0025 17.6 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75811.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM75811.1 - 0.029 14.4 2.6 0.035 14.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn helix MARVEL PF01284.23 KFM75812.1 - 8.6e-12 45.3 14.4 1.3e-11 44.7 14.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain SmpA_OmlA PF04355.13 KFM75812.1 - 0.03 14.1 0.2 0.055 13.3 0.2 1.4 1 0 0 1 1 1 0 SmpA / OmlA family Glyco_transf_10 PF00852.19 KFM75813.1 - 4.5e-58 195.9 0.3 4.5e-58 195.9 0.3 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFM75813.1 - 3e-33 114.6 1.8 7e-33 113.4 0.8 2.1 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Prim_Zn_Ribbon PF08273.12 KFM75813.1 - 6.2 7.2 6.8 0.51 10.7 0.6 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase tRNA-synt_2c PF01411.19 KFM75814.1 - 2.2e-98 330.2 0.0 2.4e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA-synt_2c PF01411.19 KFM75815.1 - 2.6e-102 343.1 0.0 2.9e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHC_N2 PF08393.13 KFM75816.1 - 1.4e-87 294.5 22.2 1.4e-87 294.5 22.2 2.3 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 2 MHCassoc_trimer PF08831.10 KFM75816.1 - 0.038 14.0 2.0 0.32 11.0 0.2 3.4 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Apolipoprotein PF01442.18 KFM75817.1 - 2.1e-07 31.0 13.9 2.1e-07 31.0 13.9 2.8 3 0 0 3 3 3 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM75817.1 - 3.2e-07 30.5 2.2 2.8e-05 24.2 0.2 2.8 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 KFM75817.1 - 0.00076 18.9 19.0 0.0015 17.9 19.0 1.5 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF1640 PF07798.11 KFM75817.1 - 0.00092 19.3 27.1 0.007 16.4 8.2 3.1 3 1 1 4 4 2 2 Protein of unknown function (DUF1640) Prominin PF05478.11 KFM75817.1 - 0.0011 17.0 11.5 0.0017 16.4 11.5 1.2 1 0 0 1 1 1 1 Prominin DUF1664 PF07889.12 KFM75817.1 - 0.0021 18.1 22.9 0.0043 17.1 7.1 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) ApoO PF09769.9 KFM75817.1 - 0.0041 17.1 8.7 0.21 11.5 2.0 4.0 2 1 2 4 4 4 1 Apolipoprotein O Phasin PF05597.11 KFM75817.1 - 0.013 15.5 25.0 0.016 15.2 5.5 3.6 3 1 1 4 4 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HSBP1 PF06825.12 KFM75817.1 - 0.014 15.2 5.4 1.1 9.2 0.1 3.5 2 1 0 3 3 3 0 Heat shock factor binding protein 1 DUF4407 PF14362.6 KFM75817.1 - 0.017 14.5 11.5 0.033 13.6 11.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EzrA PF06160.12 KFM75817.1 - 0.046 11.9 19.7 0.035 12.3 16.9 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF1351 PF07083.11 KFM75817.1 - 0.094 12.5 20.3 0.17 11.6 11.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1351) Peptidase_S64 PF08192.11 KFM75817.1 - 0.099 11.1 10.6 0.17 10.3 10.6 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF1690 PF07956.11 KFM75817.1 - 0.11 13.0 18.1 0.77 10.2 2.4 3.3 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) DUF725 PF05267.12 KFM75817.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF725) DUF3584 PF12128.8 KFM75817.1 - 0.13 9.7 18.1 0.24 8.9 18.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spore_III_AB PF09548.10 KFM75817.1 - 0.27 11.3 10.9 0.75 9.9 10.4 2.1 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF5082 PF16888.5 KFM75817.1 - 0.34 11.2 15.4 9.1 6.6 0.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) CdvA PF18822.1 KFM75817.1 - 0.36 10.6 26.5 1.7 8.5 3.5 4.6 2 1 3 5 5 5 0 CdvA-like coiled-coil domain DUF883 PF05957.13 KFM75817.1 - 0.42 11.2 23.0 0.55 10.9 3.5 4.1 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF883) Fzo_mitofusin PF04799.13 KFM75817.1 - 0.47 10.0 17.1 0.62 9.6 3.4 3.2 1 1 2 3 3 3 0 fzo-like conserved region WXG100 PF06013.12 KFM75817.1 - 1 9.6 14.1 2.6 8.4 4.1 3.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG SpoIISA_toxin PF14171.6 KFM75817.1 - 1.4 8.6 7.2 2.4 7.8 7.2 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF16 PF01519.16 KFM75817.1 - 1.9 9.0 22.2 2.4 8.7 9.6 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF148 PF02520.17 KFM75817.1 - 1.9 8.6 22.1 0.18 11.9 6.5 3.2 2 1 2 4 4 3 0 Domain of unknown function DUF148 FliG_M PF14841.6 KFM75817.1 - 2.3 8.5 11.3 2.4 8.4 0.1 3.5 3 1 0 3 3 3 0 FliG middle domain LMBR1 PF04791.16 KFM75817.1 - 2.4 7.0 6.2 4.4 6.1 6.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein IFT57 PF10498.9 KFM75817.1 - 2.4 7.0 19.6 14 4.5 19.6 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 COG2 PF06148.11 KFM75817.1 - 4 7.5 27.6 0.6 10.2 2.5 4.7 2 1 3 5 5 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_M75 PF09375.10 KFM75817.1 - 4.2 6.8 8.8 1.4 8.3 5.7 1.8 2 0 0 2 2 1 0 Imelysin LacI PF00356.21 KFM75817.1 - 4.9 7.0 6.0 9.4 6.1 0.6 2.9 1 1 1 2 2 2 0 Bacterial regulatory proteins, lacI family CLZ PF16526.5 KFM75817.1 - 5.2 7.5 16.7 0.6 10.5 2.5 4.4 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MnmE_helical PF12631.7 KFM75817.1 - 5.2 7.2 11.4 0.32 11.1 3.9 2.3 1 1 1 2 2 2 0 MnmE helical domain NPV_P10 PF05531.12 KFM75817.1 - 6 7.4 16.3 49 4.5 7.6 4.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Nup88 PF10168.9 KFM75817.1 - 6.4 4.4 18.3 12 3.6 18.3 1.4 1 0 0 1 1 1 0 Nuclear pore component Hemagglutinin PF00509.18 KFM75817.1 - 6.8 5.0 8.3 7.6 4.8 7.2 1.5 1 1 0 1 1 1 0 Haemagglutinin HalX PF08663.10 KFM75817.1 - 8.6 6.8 10.0 14 6.1 0.1 3.9 3 1 1 4 4 3 0 HalX domain DUF1451 PF07295.11 KFM75817.1 - 9 6.3 18.4 1.4 9.0 6.9 2.9 2 1 1 3 3 2 0 Zinc-ribbon containing domain FAD_binding_7 PF03441.14 KFM75819.1 - 0.026 14.0 3.4 0.034 13.6 1.2 2.2 2 1 0 2 2 2 0 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFM75820.1 - 2.3e-09 37.4 0.1 3.5e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase CarboxypepD_reg PF13620.6 KFM75821.1 - 1.4e-39 134.2 0.0 3.4e-07 30.4 0.0 9.2 9 0 0 9 9 9 7 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 KFM75821.1 - 3.3e-23 82.1 1.0 0.008 16.3 0.0 9.1 8 3 2 11 11 10 5 Protein of unknown function (DUF2012) SdrD_B PF17210.3 KFM75821.1 - 1.9e-22 79.6 0.1 0.00015 22.0 0.0 7.5 6 1 1 7 7 7 5 SdrD B-like domain CarbopepD_reg_2 PF13715.6 KFM75821.1 - 3.8e-21 74.9 1.8 0.0007 19.5 0.2 8.1 8 0 0 8 8 8 4 CarboxypepD_reg-like domain SpaA PF17802.1 KFM75821.1 - 1.2e-15 57.5 0.3 0.00019 21.7 0.0 6.8 7 0 0 7 7 7 2 Prealbumin-like fold domain fn3_3 PF14686.6 KFM75821.1 - 1.6e-09 37.4 0.2 0.032 14.0 0.0 5.6 7 0 0 7 7 7 3 Polysaccharide lyase family 4, domain II DUF3823 PF12866.7 KFM75821.1 - 1.5e-05 25.2 2.7 3.6 7.9 0.0 5.6 5 1 1 6 6 6 2 Protein of unknown function (DUF3823) N-terminal domain MG4 PF17789.1 KFM75821.1 - 0.00013 22.1 0.0 0.0029 17.7 0.0 2.9 2 0 0 2 2 2 1 Macroglobulin domain MG4 Y_Y_Y PF07495.13 KFM75821.1 - 0.00015 21.7 6.0 0.77 9.8 0.1 4.9 5 0 0 5 5 4 2 Y_Y_Y domain DUF4198 PF10670.9 KFM75821.1 - 0.008 16.6 0.0 25 5.1 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4198) Dioxygenase_C PF00775.21 KFM75821.1 - 0.025 14.0 0.1 16 4.9 0.0 4.7 4 1 1 5 5 5 0 Dioxygenase DUF104 PF01954.16 KFM75821.1 - 0.091 13.2 0.0 0.61 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF104 Fungal_trans PF04082.18 KFM75822.1 - 0.19 10.7 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Tubulin_C PF03953.17 KFM75823.1 - 0.15 12.2 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Tubulin C-terminal domain UCH PF00443.29 KFM75824.1 - 3e-08 33.5 0.1 3.1e-08 33.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM75824.1 - 0.0024 17.5 0.0 0.0024 17.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KFM75825.1 - 1.8e-21 76.8 23.7 4e-17 62.6 23.7 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tipalpha PF16753.5 KFM75825.1 - 1.2 9.0 5.5 1.9 8.3 2.5 2.3 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter zf-C3HC4_4 PF15227.6 KFM75825.1 - 1.3 9.3 19.7 0.84 9.8 15.8 3.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DSPc PF00782.20 KFM75825.1 - 2.9 7.7 6.3 60 3.5 3.8 2.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Rdx PF10262.9 KFM75826.1 - 2.3e-06 27.7 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Rdx family p450 PF00067.22 KFM75827.1 - 3.1e-97 326.2 0.6 4.1e-97 325.8 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5585 PF17823.1 KFM75827.1 - 0.65 8.9 1.3 0.96 8.3 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Oxidored_q5_N PF01059.17 KFM75828.1 - 0.066 13.3 0.1 0.066 13.3 0.1 3.5 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus ETF PF01012.21 KFM75829.1 - 7.8e-38 130.2 2.6 1.2e-37 129.5 2.6 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KFM75829.1 - 3.4e-37 126.3 0.2 8.5e-37 125.1 0.2 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain PPS_PS PF02006.16 KFM75829.1 - 0.041 13.4 0.2 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphopantothenate/pantothenate synthetase Pkinase_Tyr PF07714.17 KFM75830.1 - 1.2e-89 300.1 0.0 1.5e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM75830.1 - 2.7e-47 161.4 0.0 3.7e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFM75830.1 - 1.6e-25 89.0 0.1 5e-25 87.4 0.1 1.9 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.28 KFM75830.1 - 1.3e-11 43.9 0.0 3.3e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM75830.1 - 6e-07 29.2 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM75830.1 - 1.2e-06 28.0 0.0 3.8e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 KFM75830.1 - 0.0075 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM75830.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFM75830.1 - 0.057 12.3 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Glyoxalase PF00903.25 KFM75831.1 - 1.5e-12 47.8 0.0 4e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFM75831.1 - 2.4e-06 28.3 0.0 0.0032 18.3 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.6 KFM75831.1 - 2.4e-05 24.4 0.1 0.0068 16.5 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_4 PF13669.6 KFM75831.1 - 0.073 13.4 0.0 6 7.2 0.0 2.6 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tau95 PF09734.9 KFM75833.1 - 6.3e-34 117.8 1.4 1.8e-33 116.3 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KFM75833.1 - 1e-23 83.9 0.5 2.2e-23 82.9 0.1 1.8 2 0 0 2 2 2 1 Tau95 Triple barrel domain DDE_3 PF13358.6 KFM75834.1 - 0.00035 20.3 0.6 0.002 17.9 0.6 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease GST_C_2 PF13410.6 KFM75835.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM75835.1 - 0.00023 21.3 0.0 0.00045 20.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFM75835.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFM75835.1 - 0.0027 17.4 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 7tm_1 PF00001.21 KFM75836.1 - 1.1e-49 169.2 13.6 1.3e-49 168.9 13.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM75836.1 - 4.6e-09 36.0 8.9 6.5e-09 35.6 8.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM75836.1 - 2e-07 30.9 13.2 2.7e-07 30.5 13.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFM75836.1 - 0.00017 21.4 7.5 0.012 15.3 7.5 2.9 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 KFM75836.1 - 0.01 15.1 13.3 0.024 14.0 13.3 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srt PF10321.9 KFM75836.1 - 0.15 11.0 13.3 0.25 10.3 13.3 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt DDE_3 PF13358.6 KFM75837.1 - 1.3e-14 54.2 0.0 1.7e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75838.1 - 2.3e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75838.1 - 4.5e-13 49.2 0.0 7.3e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease 14-3-3 PF00244.20 KFM75839.1 - 5.6e-109 362.8 6.8 6.4e-109 362.7 6.8 1.0 1 0 0 1 1 1 1 14-3-3 protein PhoU_div PF01865.16 KFM75839.1 - 0.037 13.3 0.5 0.21 10.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF47 CIA30 PF08547.12 KFM75839.1 - 0.092 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) FliM PF02154.15 KFM75839.1 - 0.16 11.8 0.2 0.27 11.1 0.2 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM DUF4710 PF15828.5 KFM75839.1 - 0.83 9.8 7.2 2.6 8.2 0.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4710) Exo_endo_phos_2 PF14529.6 KFM75840.1 - 0.00019 21.3 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM75840.1 - 0.094 12.2 0.5 0.16 11.5 0.5 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family FAT PF02259.23 KFM75841.1 - 3.1e-59 200.9 5.0 3.1e-59 200.9 5.0 2.6 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 KFM75841.1 - 9e-18 65.0 0.0 2.7e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFM75841.1 - 0.00011 22.0 0.1 0.00039 20.2 0.1 2.0 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 KFM75841.1 - 0.0044 17.0 0.7 5.7 7.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM75841.1 - 0.011 16.5 3.5 17 6.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_M7 PF02031.16 KFM75841.1 - 0.097 12.8 0.1 1.6 8.9 0.1 2.3 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Cnd1 PF12717.7 KFM75842.1 - 0.026 14.6 4.4 1.5 8.9 0.0 4.0 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 SPG48 PF14764.6 KFM75842.1 - 0.029 14.8 0.7 1.7 9.1 0.1 3.2 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking Cnd3 PF12719.7 KFM75842.1 - 0.034 13.4 4.2 0.25 10.5 0.3 3.4 2 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain DUF5071 PF16804.5 KFM75842.1 - 0.08 13.2 2.2 0.79 10.0 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5071) GatB_Yqey PF02637.18 KFM75842.1 - 0.11 12.3 0.9 1.8 8.4 0.4 2.8 2 0 0 2 2 2 0 GatB domain RecG_N PF17190.4 KFM75842.1 - 1.2 9.9 3.9 1.3 9.8 0.3 3.0 3 0 0 3 3 3 0 RecG N-terminal helical domain TRC8_N PF13705.6 KFM75843.1 - 0.048 12.6 1.6 0.095 11.6 1.6 1.4 1 0 0 1 1 1 0 TRC8 N-terminal domain MIF4G PF02854.19 KFM75844.1 - 0.085 12.5 4.3 2.4 7.8 0.1 2.6 3 0 0 3 3 3 0 MIF4G domain Sec7_N PF12783.7 KFM75844.1 - 0.94 9.4 17.1 4.1 7.3 2.7 4.6 3 2 2 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CaMKII_AD PF08332.10 KFM75846.1 - 4e-61 204.8 0.0 5.1e-61 204.5 0.0 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 KFM75846.1 - 1.6e-09 38.1 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KFM75846.1 - 4.4e-08 33.4 0.0 6.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain She2p PF11435.8 KFM75846.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein She2p Pkinase PF00069.25 KFM75848.1 - 1.5e-19 70.4 0.1 1.6e-19 70.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM75848.1 - 7.4e-11 41.8 0.0 8.4e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Patched PF02460.18 KFM75849.1 - 3.2e-197 657.3 13.8 4e-197 657.0 13.8 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFM75849.1 - 4.8e-38 130.4 2.2 4.8e-38 130.4 2.2 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation DUF2701 PF10857.8 KFM75849.1 - 8.9 6.4 6.8 9.7 6.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2701) DAN PF03045.15 KFM75851.1 - 6.1e-05 23.0 9.5 9.5e-05 22.4 9.5 1.2 1 0 0 1 1 1 1 DAN domain MbeD_MobD PF04899.12 KFM75852.1 - 0.025 14.7 0.1 0.052 13.7 0.1 1.5 1 0 0 1 1 1 0 MbeD/MobD like MCM_N PF14551.6 KFM75852.1 - 0.17 12.5 0.0 0.32 11.6 0.0 1.4 1 0 0 1 1 1 0 MCM N-terminal domain Transposase_1 PF01359.18 KFM75853.1 - 2.7e-18 65.6 0.0 4.8e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_Tnp_Tc3_2 PF01498.18 KFM75853.1 - 1.1e-14 54.5 5.2 1.1e-14 54.4 3.6 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75853.1 - 0.00032 20.5 0.0 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM75853.1 - 0.00036 21.1 0.8 0.00036 21.1 0.8 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM75855.1 - 2.4e-16 59.7 2.3 3.8e-16 59.1 0.7 2.1 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KFM75855.1 - 0.0007 20.2 5.3 0.019 15.5 1.7 2.7 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.6 KFM75855.1 - 0.004 16.9 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 2 DDE superfamily endonuclease MarR_2 PF12802.7 KFM75855.1 - 0.0073 16.2 0.7 0.77 9.7 0.1 2.5 2 0 0 2 2 2 1 MarR family PIP49_C PF12260.8 KFM75855.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 HTH_Crp_2 PF13545.6 KFM75855.1 - 0.092 12.7 0.7 0.26 11.3 0.1 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain PAX PF00292.18 KFM75855.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 'Paired box' domain RNase_H PF00075.24 KFM75857.1 - 3.3e-12 46.8 4.6 9.4e-12 45.3 4.6 1.7 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM75857.1 - 4.2e-07 29.8 1.6 5.8e-07 29.4 1.6 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like DDE_3 PF13358.6 KFM75858.1 - 3e-10 40.0 0.0 4.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Carbpep_Y_N PF05388.11 KFM75858.1 - 0.027 15.0 0.9 0.044 14.3 0.1 1.7 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide HTH_Tnp_Tc3_2 PF01498.18 KFM75859.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75859.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75859.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75859.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75859.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Acyl-CoA_dh_N PF02771.16 KFM75861.1 - 1.7e-27 96.3 0.0 3.9e-27 95.2 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM75861.1 - 6e-20 71.3 0.0 9e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFM75861.1 - 7.3e-13 49.0 0.0 1.2e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KFM75861.1 - 0.0039 17.5 0.0 0.0067 16.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFM75861.1 - 0.22 11.1 0.0 22 4.6 0.0 2.2 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal zf-Di19 PF05605.12 KFM75862.1 - 2.7e-19 69.2 1.1 9.1e-19 67.5 1.1 1.9 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.17 KFM75862.1 - 6.8e-10 38.6 7.0 6.8e-10 38.6 7.0 2.0 2 0 0 2 2 2 1 Zinc finger, ZZ type Elf1 PF05129.13 KFM75862.1 - 0.031 14.3 0.1 0.031 14.3 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like EF-hand_8 PF13833.6 KFM75862.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair zf-Mss51 PF13824.6 KFM75862.1 - 0.2 11.8 3.7 6.2 7.0 2.5 2.7 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_5 PF14634.6 KFM75862.1 - 2.6 8.1 11.5 2.2 8.3 0.9 3.7 3 1 0 3 3 3 0 zinc-RING finger domain Zn_Tnp_IS1595 PF12760.7 KFM75862.1 - 4 7.5 7.2 4.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain DDE_3 PF13358.6 KFM75863.1 - 0.06 13.1 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease CAAD PF14159.6 KFM75863.1 - 0.17 11.7 0.4 0.31 10.9 0.4 1.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Vps54 PF07928.12 KFM75864.1 - 4.2e-50 169.7 1.0 4.2e-50 169.7 1.0 3.0 3 1 0 3 3 3 1 Vps54-like protein Sec10 PF07393.11 KFM75864.1 - 3.5e-05 22.4 0.4 5.7e-05 21.8 0.4 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF4883 PF16224.5 KFM75864.1 - 0.0032 17.7 1.9 0.095 13.0 0.3 2.6 2 0 0 2 2 2 1 DOmain of unknown function (DUF4883) DUF3271 PF11675.8 KFM75864.1 - 0.017 14.4 0.9 0.034 13.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) MLD PF11647.8 KFM75864.1 - 0.037 14.3 0.0 0.17 12.2 0.0 2.2 1 0 0 1 1 1 0 Membrane Localization Domain DNA_repr_REX1B PF14966.6 KFM75864.1 - 2 9.1 7.2 14 6.4 0.1 3.7 2 2 1 3 3 3 0 DNA repair REX1-B AMP-binding_C PF13193.6 KFM75867.1 - 1.8e-22 80.1 0.0 2.7e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFM75867.1 - 1.9e-09 36.6 0.1 2.5e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KFM75868.1 - 3.3e-42 144.6 0.0 3.5e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Endothelin PF00322.17 KFM75868.1 - 0.34 10.5 2.9 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Endothelin family ACAS_N PF16177.5 KFM75869.1 - 1.5e-17 63.2 2.3 2.4e-17 62.6 2.3 1.3 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding PF00501.28 KFM75869.1 - 1.5e-15 56.8 0.0 1.9e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HTH_Tnp_Tc3_2 PF01498.18 KFM75870.1 - 2.1e-16 59.9 2.2 4.1e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75870.1 - 8.4e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Sema PF01403.19 KFM75871.1 - 4.1e-55 187.3 0.0 5.3e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFM75871.1 - 1.1e-06 29.1 7.5 2.8e-06 27.8 7.5 1.8 1 0 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 KFM75871.1 - 0.04 13.7 5.9 0.072 12.8 5.9 1.5 1 0 0 1 1 1 0 Integrin plexin domain PARG_cat PF05028.14 KFM75872.1 - 3.3e-125 417.9 0.0 4.2e-125 417.5 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) CNDH2_C PF16858.5 KFM75873.1 - 1.9e-36 126.5 11.6 6.8e-36 124.7 6.1 2.5 2 0 0 2 2 2 2 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 KFM75873.1 - 2e-21 76.3 1.1 5.4e-20 71.7 0.4 2.8 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Cnd2 PF05786.14 KFM75873.1 - 5.2e-05 22.1 0.1 5.2e-05 22.1 0.1 2.9 2 1 1 3 3 3 1 Condensin complex subunit 2 Rad21_Rec8_N PF04825.13 KFM75873.1 - 0.0007 19.7 0.1 0.0021 18.2 0.1 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein DNA_ligase_ZBD PF03119.16 KFM75874.1 - 0.00025 21.0 1.3 0.00089 19.2 1.3 2.0 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain F-box-like PF12937.7 KFM75874.1 - 0.0012 18.7 0.2 0.0026 17.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM75874.1 - 0.024 14.5 0.3 0.055 13.4 0.3 1.6 1 0 0 1 1 1 0 F-box domain IBR PF01485.21 KFM75874.1 - 0.51 10.6 15.2 0.26 11.6 10.6 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain CNDH2_C PF16858.5 KFM75876.1 - 1.2e-09 38.5 0.0 1.2e-09 38.5 0.0 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Rad21_Rec8 PF04824.16 KFM75876.1 - 0.0082 15.4 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein HTH_Tnp_Tc3_2 PF01498.18 KFM75877.1 - 5.3e-16 58.6 3.5 6e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75877.1 - 1.4e-13 50.8 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75877.1 - 2.1e-07 30.6 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75877.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75877.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Mpp10 PF04006.12 KFM75879.1 - 6 5.2 13.0 6.8 5.0 13.0 1.0 1 0 0 1 1 1 0 Mpp10 protein zf-H2C2_2 PF13465.6 KFM75881.1 - 5.8e-108 349.0 81.7 1e-09 38.3 0.7 15.1 15 0 0 15 15 15 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75881.1 - 3.2e-65 213.1 109.3 3.1e-06 27.3 1.1 13.2 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75881.1 - 3.1e-53 173.8 111.9 5.3e-05 23.7 1.4 13.7 14 0 0 14 14 14 13 C2H2-type zinc finger zf-met PF12874.7 KFM75881.1 - 5.7e-31 106.0 114.7 0.00062 20.1 2.4 13.3 13 0 0 13 13 13 11 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM75881.1 - 1.9e-19 69.0 55.3 0.022 14.5 0.1 13.2 13 0 0 13 13 13 10 C2H2-type zinc-finger domain Tox-HNH-HHH PF15637.6 KFM75881.1 - 4.5e-16 58.9 0.2 0.051 13.7 0.0 6.1 1 1 4 6 6 6 4 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_6 PF13912.6 KFM75881.1 - 1.1e-15 57.1 103.3 0.067 13.2 1.8 13.8 14 0 0 14 14 14 11 C2H2-type zinc finger BolA PF01722.18 KFM75881.1 - 3.3e-11 43.3 9.6 0.11 12.7 0.0 8.9 1 1 7 8 8 8 1 BolA-like protein zf-C2H2_11 PF16622.5 KFM75881.1 - 3.6e-10 39.4 91.3 0.023 14.5 2.3 13.1 13 0 0 13 13 13 7 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM75881.1 - 5.5e-08 32.9 81.6 0.064 13.6 0.1 13.0 13 0 0 13 13 13 5 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFM75881.1 - 3.4e-06 26.8 67.7 2 8.3 0.6 12.8 5 3 8 13 13 13 4 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM75881.1 - 6.3e-06 26.1 50.5 2.1 8.4 1.3 12.7 8 3 5 13 13 13 3 Sec23/Sec24 zinc finger Zf_RING PF16744.5 KFM75881.1 - 2.2e-05 24.5 74.0 1.2 9.3 0.8 13.2 2 2 8 11 11 11 4 KIAA1045 RING finger GAGA PF09237.11 KFM75881.1 - 2.5e-05 24.0 26.8 1.2 9.0 0.0 9.7 2 2 9 11 11 11 2 GAGA factor zf-DBF PF07535.12 KFM75881.1 - 0.0042 17.2 73.7 6.4 7.0 0.6 13.2 13 0 0 13 13 13 1 DBF zinc finger TRAF6_Z2 PF18048.1 KFM75881.1 - 0.0079 16.3 73.8 0.7 10.0 2.2 12.7 13 0 0 13 13 13 3 TNF receptor-associated factor 6 zinc finger 2 zf-FPG_IleRS PF06827.14 KFM75881.1 - 0.011 15.6 40.4 1.2 9.0 0.1 12.0 13 0 0 13 13 13 0 Zinc finger found in FPG and IleRS zf-MYST PF17772.1 KFM75881.1 - 0.029 14.0 74.2 2.1 8.0 0.2 12.6 5 3 8 13 13 13 0 MYST family zinc finger domain TAFII28 PF04719.14 KFM75881.1 - 0.037 14.1 0.5 9.8 6.4 0.0 3.8 3 2 0 3 3 3 0 hTAFII28-like protein conserved region zf-C2HC_2 PF13913.6 KFM75881.1 - 0.039 13.9 51.9 1.3 9.0 0.2 12.7 13 0 0 13 13 13 0 zinc-finger of a C2HC-type DUF5330 PF17264.2 KFM75881.1 - 0.044 13.8 42.8 13 5.9 0.2 11.9 13 0 0 13 13 13 0 Family of unknown function (DUF5330) C1_4 PF07975.12 KFM75881.1 - 0.11 12.7 80.8 0.17 12.1 4.1 10.0 2 2 8 11 11 11 0 TFIIH C1-like domain C1_1 PF00130.22 KFM75881.1 - 0.31 10.9 80.4 0.31 10.9 4.0 9.8 3 2 7 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Viral_cys_rich PF08008.12 KFM75881.1 - 0.58 10.2 31.1 3.7 7.7 0.3 7.4 3 3 4 8 8 8 0 Viral cysteine rich PHD PF00628.29 KFM75881.1 - 1.7 8.6 75.9 0.36 10.7 4.1 7.7 4 2 2 7 7 7 0 PHD-finger Zn_ribbon_SprT PF17283.2 KFM75881.1 - 3.8 7.5 38.0 0.99 9.4 0.4 9.3 5 4 6 11 11 10 0 SprT-like zinc ribbon domain RT_RNaseH_2 PF17919.1 KFM75882.1 - 5.7e-15 55.2 0.0 7.1e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pex2_Pex12 PF04757.14 KFM75883.1 - 3.4e-32 111.9 6.2 4e-32 111.6 6.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KFM75883.1 - 2.9e-05 23.8 2.8 4.8e-05 23.1 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM75883.1 - 9.5e-05 22.2 1.0 0.00015 21.5 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM75883.1 - 0.00022 21.5 2.8 0.00041 20.6 2.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFM75883.1 - 0.00074 19.3 3.3 0.0013 18.6 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM75883.1 - 0.0019 18.2 5.5 0.0035 17.4 5.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFM75883.1 - 0.015 15.6 2.7 0.028 14.7 2.7 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM75883.1 - 0.63 10.0 4.3 1.7 8.7 4.4 1.6 1 1 1 2 2 2 0 zinc-RING finger domain Septin PF00735.18 KFM75885.1 - 1.9e-121 404.7 1.9 2.8e-121 404.1 1.9 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFM75885.1 - 6.4e-09 35.9 1.1 1.1e-08 35.2 0.1 2.1 2 2 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM75885.1 - 5.9e-07 29.5 0.4 0.00011 22.2 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KFM75885.1 - 0.00011 22.7 7.5 0.00046 20.8 7.5 1.9 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.16 KFM75885.1 - 0.00025 20.5 1.0 0.00041 19.8 0.0 1.9 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 KFM75885.1 - 0.00036 20.1 7.5 0.017 14.6 0.1 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.22 KFM75885.1 - 0.0011 18.6 0.4 0.0035 17.0 0.1 2.1 2 0 0 2 2 2 1 Ras family Dynamin_N PF00350.23 KFM75885.1 - 0.0024 17.9 5.4 0.42 10.6 0.1 3.5 3 1 1 4 4 4 2 Dynamin family AAA_22 PF13401.6 KFM75885.1 - 0.0062 16.8 0.5 0.13 12.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 KFM75885.1 - 0.0093 16.2 0.2 0.037 14.2 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KFM75885.1 - 0.034 14.7 2.0 0.078 13.5 0.1 2.3 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 KFM75885.1 - 0.038 14.4 0.2 0.77 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain HAUS6_N PF14661.6 KFM75885.1 - 0.042 13.4 1.3 0.089 12.4 1.3 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MukF_M PF17192.4 KFM75885.1 - 0.047 13.4 1.7 1.3 8.7 0.2 3.1 2 1 2 4 4 4 0 MukF middle domain Rx_N PF18052.1 KFM75885.1 - 0.091 13.0 2.1 0.19 12.0 0.6 2.3 2 0 0 2 2 2 0 Rx N-terminal domain AAA_7 PF12775.7 KFM75885.1 - 0.093 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AbiH PF14253.6 KFM75885.1 - 0.095 12.6 2.6 2.6 7.8 0.0 2.5 3 0 0 3 3 3 0 Bacteriophage abortive infection AbiH Formyl_trans_N PF00551.19 KFM75885.1 - 0.17 11.6 0.4 1.3 8.7 0.2 2.0 2 0 0 2 2 2 0 Formyl transferase OmpH PF03938.14 KFM75885.1 - 5.7 7.3 12.6 0.2 12.0 5.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HH_signal PF01085.18 KFM75886.1 - 9.1e-30 103.4 0.0 1.1e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain XLF PF09302.11 KFM75887.1 - 5.1e-07 30.0 0.5 5.1e-07 30.0 0.5 2.1 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Methyltr_RsmF_N PF17125.5 KFM75887.1 - 0.12 12.9 0.3 3.2 8.3 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF T6PP_N PF18572.1 KFM75887.1 - 0.54 10.1 4.2 4.1 7.3 0.4 2.7 2 1 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain TAF4 PF05236.14 KFM75888.1 - 6.5e-72 242.6 16.7 1e-71 241.9 16.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF PF02969.17 KFM75888.1 - 0.0026 17.9 0.9 0.7 10.1 0.0 2.8 2 1 1 3 3 3 2 TATA box binding protein associated factor (TAF) PTH2 PF01981.16 KFM75888.1 - 0.23 11.7 2.1 0.51 10.6 2.1 1.6 1 1 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 TMA7 PF09072.10 KFM75888.1 - 5.3 8.0 10.4 3.9 8.4 8.1 2.0 1 1 1 2 2 2 0 Translation machinery associated TMA7 LSM14 PF12701.7 KFM75891.1 - 3.2e-32 110.5 0.0 6.3e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KFM75891.1 - 1.9e-11 44.8 12.1 1.3e-10 42.1 4.5 3.5 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KFM75891.1 - 1e-08 35.2 0.0 2.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2753 PF10952.8 KFM75892.1 - 0.045 13.9 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) HTH_Tnp_Tc3_2 PF01498.18 KFM75893.1 - 1.3e-15 57.4 8.5 6.4e-15 55.2 6.5 2.4 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75893.1 - 7.4e-15 55.0 0.1 3.8e-14 52.7 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM75893.1 - 2.5e-05 24.0 0.1 7.3e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) HTH_23 PF13384.6 KFM75893.1 - 0.0013 18.4 0.3 0.42 10.5 0.0 3.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75893.1 - 0.003 18.1 1.5 0.003 18.1 1.5 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM75893.1 - 0.0048 16.9 2.2 0.13 12.3 0.2 2.9 3 0 0 3 3 3 1 Winged helix-turn helix HTH_7 PF02796.15 KFM75893.1 - 0.072 13.2 0.5 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KFM75893.1 - 0.076 13.2 0.1 0.24 11.6 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain AAA PF00004.29 KFM75895.1 - 9.5e-28 97.2 0.0 1e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 KFM75896.1 - 3.1e-30 105.5 0.0 4.6e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 KFM75896.1 - 3.4e-14 52.4 0.1 5e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 AAA+ lid domain Vault_3 PF17795.1 KFM75896.1 - 0.096 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Major Vault Protein Repeat domain Peptidase_M50B PF13398.6 KFM75896.1 - 0.21 11.2 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M41 PF01434.18 KFM75897.1 - 0.042 13.7 1.0 0.052 13.4 1.0 1.1 1 0 0 1 1 1 0 Peptidase family M41 Forkhead PF00250.18 KFM75898.1 - 3.7e-11 43.1 0.1 5.1e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Forkhead domain Sec62 PF03839.16 KFM75899.1 - 1.6e-72 243.6 7.5 1.6e-72 243.6 7.5 3.0 2 1 1 3 3 3 1 Translocation protein Sec62 SpoIIIAH PF12685.7 KFM75899.1 - 0.00031 20.6 11.4 0.017 14.9 1.0 2.8 3 0 0 3 3 3 2 SpoIIIAH-like protein OPT PF03169.15 KFM75899.1 - 0.00035 19.4 0.0 0.00046 19.0 0.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SID-1_RNA_chan PF13965.6 KFM75899.1 - 0.0087 14.5 4.5 0.08 11.3 0.0 2.1 1 1 0 2 2 2 1 dsRNA-gated channel SID-1 DUF5308 PF17233.2 KFM75899.1 - 0.064 13.5 1.7 3.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Dsh_C PF12316.8 KFM75899.1 - 0.31 11.4 8.0 3.7 7.9 0.2 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal V_ATPase_I PF01496.19 KFM75899.1 - 2.8 5.8 20.5 0.44 8.4 4.0 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 KFM75899.1 - 3.7 7.5 12.3 9.4 6.2 0.0 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4228 PF14009.6 KFM75899.1 - 5.4 7.4 10.8 3.3 8.1 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DUF4834 PF16118.5 KFM75899.1 - 5.5 8.0 28.1 0.88 10.6 9.9 3.3 3 1 0 3 3 2 0 Domain of unknown function (DUF4834) CCDC53 PF10152.9 KFM75899.1 - 7.5 6.9 17.3 0.15 12.5 2.3 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF913 PF06025.12 KFM75899.1 - 9.8 5.0 16.0 2.4 7.1 4.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TFIIF_beta PF02270.15 KFM75900.1 - 5.3e-17 61.7 1.9 6.8e-16 58.2 0.1 2.1 2 0 0 2 2 2 2 TFIIF, beta subunit HTH domain HTH_Tnp_Tc3_2 PF01498.18 KFM75901.1 - 4.4e-16 58.9 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75901.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75901.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75901.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75901.1 - 0.027 14.6 0.4 0.088 13.0 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM75901.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain EGF PF00008.27 KFM75902.1 - 1.6e-18 66.7 54.2 1e-08 35.3 7.6 4.3 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 KFM75902.1 - 6.8e-07 29.7 48.1 0.0012 19.4 7.0 5.0 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.13 KFM75902.1 - 0.00023 21.4 63.1 0.0038 17.6 10.4 4.4 4 0 0 4 4 4 3 EGF-like domain EGF_CA PF07645.15 KFM75902.1 - 0.25 11.6 56.6 13 6.1 4.6 4.7 1 1 3 4 4 4 0 Calcium-binding EGF domain HTH_Tnp_Tc3_2 PF01498.18 KFM75904.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75904.1 - 7.6e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM75905.1 - 1.9e-16 60.1 0.2 2.8e-15 56.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75905.1 - 7.5e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM75905.1 - 0.00072 20.1 1.5 0.00072 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM75905.1 - 0.0028 17.4 0.1 0.15 11.9 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75905.1 - 0.015 15.4 0.1 0.058 13.5 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM75905.1 - 0.091 12.8 2.5 0.096 12.7 0.3 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM75906.1 - 2.4e-16 59.7 5.4 1.4e-15 57.3 6.5 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75906.1 - 3.9e-05 23.4 0.0 0.0003 20.6 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM75906.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.9 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM75906.1 - 0.004 16.9 0.3 0.11 12.3 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75906.1 - 0.016 15.3 0.1 0.064 13.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM75906.1 - 0.033 14.2 2.6 0.034 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM75907.1 - 2.7e-16 59.6 2.8 5e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75907.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75907.1 - 1.7e-07 30.8 1.2 6.3e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75907.1 - 0.0023 17.6 0.6 0.0068 16.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75907.1 - 1.8 9.2 15.7 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM75908.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 1 0 1 1 1 0 DDE superfamily endonuclease DCP1 PF06058.13 KFM75909.1 - 7.1e-15 55.0 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family adh_short PF00106.25 KFM75910.1 - 2.8e-50 170.5 0.1 3.5e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM75910.1 - 3e-31 108.8 0.0 3.7e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM75910.1 - 6.5e-13 49.0 0.1 9.6e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFM75910.1 - 0.0012 18.3 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KFM75910.1 - 0.0034 16.9 0.2 0.0087 15.5 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KFM75910.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF19 PF01579.18 KFM75911.1 - 0.00017 21.4 11.7 0.034 14.0 5.9 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF19) Pkinase PF00069.25 KFM75912.1 - 5.3e-81 271.9 0.0 6.6e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM75912.1 - 6.1e-39 133.9 0.0 7.9e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM75912.1 - 1.9e-08 34.0 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM75912.1 - 1.4e-05 24.6 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM75912.1 - 0.0002 21.0 0.1 0.0002 21.0 0.1 1.7 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 KFM75912.1 - 0.0022 17.7 1.4 0.38 10.3 0.0 2.5 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 5_nucleotid PF05761.14 KFM75912.1 - 0.0079 15.1 0.3 0.015 14.3 0.3 1.3 1 0 0 1 1 1 1 5' nucleotidase family APH PF01636.23 KFM75912.1 - 0.051 13.5 0.0 0.34 10.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mrpl_C PF18502.1 KFM75912.1 - 0.081 13.2 1.8 0.7 10.2 0.3 2.4 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain RFX5_N PF18326.1 KFM75912.1 - 0.095 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 RFX5 N-terminal domain UNC-93 PF05978.16 KFM75913.1 - 1.8e-06 27.8 4.8 1.8e-06 27.8 4.8 2.6 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFM75914.1 - 1.1e-09 37.7 31.7 2.6e-07 29.9 10.4 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily UNC-93 PF05978.16 KFM75914.1 - 5.3e-08 32.7 8.1 5.3e-08 32.7 8.1 3.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 CDH PF02611.15 KFM75914.1 - 0.00029 20.5 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase TNFR_16_TM PF18422.1 KFM75914.1 - 0.2 11.7 2.5 1.1 9.3 2.5 2.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain MFS_1 PF07690.16 KFM75915.1 - 6.5e-05 22.0 12.7 7.9e-05 21.7 12.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily KRTAP PF11759.8 KFM75916.1 - 0.00013 22.5 10.3 0.00013 22.5 10.3 3.0 2 1 0 2 2 2 1 Keratin-associated matrix Chitin_bind_4 PF00379.23 KFM75917.1 - 9.3e-07 29.3 1.3 1.3e-06 28.8 1.3 1.2 1 0 0 1 1 1 1 Insect cuticle protein DDE_1 PF03184.19 KFM75922.1 - 2.7e-06 27.2 0.0 2.8e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1409 PF07197.12 KFM75922.1 - 0.15 12.0 0.5 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) PRP21_like_P PF12230.8 KFM75923.1 - 6.2e-05 23.0 54.3 0.2 11.5 0.6 9.8 7 3 4 11 11 11 6 Pre-mRNA splicing factor PRP21 like protein zf-C2HC_2 PF13913.6 KFM75923.1 - 0.0015 18.4 0.3 0.0015 18.4 0.3 11.3 14 2 0 14 14 14 1 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM75923.1 - 0.14 11.8 0.1 0.14 11.8 0.1 15.8 16 0 0 16 16 16 0 Ubiquitin-Binding Zinc Finger zf-dskA_traR PF01258.17 KFM75923.1 - 0.69 9.9 7.2 1.5 8.8 0.1 4.6 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger MIF PF01187.18 KFM75924.1 - 1.3e-37 128.6 0.0 1.4e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Aminopep PF10023.9 KFM75924.1 - 0.21 10.9 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative aminopeptidase T-box PF00907.22 KFM75925.1 - 1.6e-65 220.9 0.2 2.1e-65 220.5 0.2 1.2 1 0 0 1 1 1 1 T-box zf-H2C2_2 PF13465.6 KFM75926.1 - 4.7e-65 213.3 54.8 1.1e-07 32.0 0.4 9.1 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75926.1 - 4.3e-41 137.1 64.3 1.5e-05 25.2 1.3 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75926.1 - 2.7e-30 102.4 62.6 0.0013 19.4 0.8 9.1 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM75926.1 - 6.3e-18 64.5 54.8 0.026 14.9 2.2 9.3 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM75926.1 - 4.3e-13 48.7 42.0 0.033 13.9 0.4 8.8 9 0 0 9 9 8 6 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM75926.1 - 4.1e-12 46.1 36.4 0.14 12.5 0.1 9.5 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM75926.1 - 3.7e-10 39.5 60.3 0.17 12.0 0.4 10.0 9 1 0 9 9 9 7 C2H2-type zinc finger zf-DBF PF07535.12 KFM75926.1 - 1.5e-08 34.6 26.7 12 6.1 0.0 9.2 9 0 0 9 9 9 0 DBF zinc finger BolA PF01722.18 KFM75926.1 - 1.8e-07 31.3 6.8 3.5 8.0 0.0 6.4 1 1 6 7 7 7 1 BolA-like protein zf-C2HC_2 PF13913.6 KFM75926.1 - 5.1e-07 29.4 28.9 0.32 11.0 0.1 9.2 9 0 0 9 9 9 1 zinc-finger of a C2HC-type zf-CHCC PF10276.9 KFM75926.1 - 5.4e-06 26.4 4.5 84 3.3 0.0 8.3 9 0 0 9 9 9 0 Zinc-finger domain ADK_lid PF05191.14 KFM75926.1 - 8.7e-06 25.6 14.7 3.5 7.7 0.0 5.8 3 2 1 4 4 4 1 Adenylate kinase, active site lid FYVE PF01363.21 KFM75926.1 - 3.1e-05 24.0 41.1 0.033 14.3 7.3 6.4 1 1 4 5 5 5 3 FYVE zinc finger zf-C2H2_11 PF16622.5 KFM75926.1 - 3.8e-05 23.3 32.1 0.06 13.1 0.4 6.9 7 0 0 7 7 7 3 zinc-finger C2H2-type YyzF PF14116.6 KFM75926.1 - 5.5e-05 23.1 24.0 19 5.4 0.1 8.8 9 0 0 9 9 9 0 YyzF-like protein Tox-HNH-HHH PF15637.6 KFM75926.1 - 0.0012 18.9 0.5 0.83 9.8 0.0 3.5 2 2 1 3 3 3 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif PUF PF00806.19 KFM75926.1 - 0.0014 18.2 0.3 27 4.7 0.0 5.3 6 0 0 6 6 6 0 Pumilio-family RNA binding repeat zf-Sec23_Sec24 PF04810.15 KFM75926.1 - 0.0014 18.7 28.7 2.8 8.1 0.0 8.4 8 1 1 9 9 9 1 Sec23/Sec24 zinc finger PqqA PF08042.11 KFM75926.1 - 0.0019 18.1 5.4 3e+02 1.7 0.0 7.3 8 0 0 8 8 8 0 PqqA family Nore1-SARAH PF16517.5 KFM75926.1 - 0.0025 17.7 0.0 5.1 7.1 0.0 4.8 6 0 0 6 6 5 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain zinc_ribbon_15 PF17032.5 KFM75926.1 - 0.01 16.6 26.7 0.43 11.4 0.5 4.8 2 1 2 4 4 4 0 zinc-ribbon family DUF3396 PF11876.8 KFM75926.1 - 0.011 15.2 0.0 15 5.0 0.0 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF3396) zf-RRPl_C4 PF17026.5 KFM75926.1 - 0.055 13.6 28.4 1.1 9.3 1.7 4.2 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF5330 PF17264.2 KFM75926.1 - 0.098 12.7 20.4 91 3.2 0.0 8.2 9 0 0 9 9 9 0 Family of unknown function (DUF5330) FYDLN_acid PF09538.10 KFM75926.1 - 0.1 13.3 16.6 76 4.1 0.2 6.8 1 1 6 7 7 7 0 Protein of unknown function (FYDLN_acid) zf-HIT PF04438.16 KFM75926.1 - 0.17 11.7 40.4 19 5.2 0.2 8.9 9 0 0 9 9 9 0 HIT zinc finger zf_UBZ PF18439.1 KFM75926.1 - 0.21 11.2 34.9 13 5.5 0.1 8.7 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFM75926.1 - 0.23 12.1 26.9 28 5.4 0.8 6.7 1 1 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats C5HCH PF17982.1 KFM75926.1 - 0.25 11.5 36.9 11 6.2 3.1 8.6 5 2 2 8 8 8 0 NSD Cys-His rich domain DUF2256 PF10013.9 KFM75926.1 - 0.34 11.1 29.1 51 4.1 0.0 8.6 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) HNH_5 PF14279.6 KFM75926.1 - 0.34 10.8 31.9 14 5.6 0.1 8.2 5 3 1 7 7 7 0 HNH endonuclease zf-MYST PF17772.1 KFM75926.1 - 0.41 10.3 36.2 15 5.3 0.2 8.4 3 2 6 9 9 9 0 MYST family zinc finger domain zf-RING_UBOX PF13445.6 KFM75926.1 - 0.74 9.9 22.5 4.7 7.3 2.2 6.8 7 1 0 7 7 7 0 RING-type zinc-finger DUF4990 PF16380.5 KFM75926.1 - 1 9.5 2.5 97 3.1 0.1 4.6 3 1 3 6 6 6 0 Domain of unknown function RecR PF02132.15 KFM75926.1 - 1.1 8.8 35.0 10 5.7 0.1 7.9 7 2 0 7 7 7 0 RecR protein GAGA PF09237.11 KFM75926.1 - 1.3 8.9 25.4 8.6 6.3 0.1 7.5 1 1 8 9 9 9 0 GAGA factor zf-H2C2_2 PF13465.6 KFM75927.1 - 5.3e-94 304.8 100.2 3e-08 33.7 0.8 15.1 15 0 0 15 15 15 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75927.1 - 2.1e-68 223.1 111.7 6.6e-06 26.3 1.6 14.4 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75927.1 - 1.5e-51 168.6 110.2 0.00078 20.1 0.5 14.7 15 0 0 15 15 15 14 C2H2-type zinc finger zf-met PF12874.7 KFM75927.1 - 7.2e-35 118.4 103.3 0.0028 18.0 3.6 14.5 14 0 0 14 14 14 14 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM75927.1 - 1.8e-24 85.1 76.1 0.0046 16.7 1.5 14.5 14 0 0 14 14 14 10 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM75927.1 - 1.8e-12 47.0 88.8 0.29 11.2 1.5 14.9 14 0 0 14 14 14 6 C2H2-type zinc finger BolA PF01722.18 KFM75927.1 - 2.6e-12 46.8 19.9 0.8 10.0 0.2 9.6 1 1 7 9 9 9 4 BolA-like protein zf-Di19 PF05605.12 KFM75927.1 - 9.8e-11 41.8 88.3 0.12 12.6 3.5 12.3 1 1 11 13 13 13 10 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFM75927.1 - 6.2e-10 39.1 73.3 0.18 12.2 0.7 14.3 14 0 0 14 14 14 5 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM75927.1 - 3.2e-07 30.1 50.6 1.9 8.5 0.1 13.5 14 0 0 14 14 14 4 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM75927.1 - 3.3e-07 30.3 56.9 9.9 6.4 0.0 13.7 14 0 0 14 14 14 0 DBF zinc finger ADK_lid PF05191.14 KFM75927.1 - 1e-06 28.6 33.2 0.98 9.5 0.6 8.4 4 2 2 6 6 6 2 Adenylate kinase, active site lid GAGA PF09237.11 KFM75927.1 - 8.7e-06 25.5 40.3 1.5 8.7 0.0 11.1 1 1 11 13 13 13 4 GAGA factor zf-C2H2_11 PF16622.5 KFM75927.1 - 0.00021 21.0 77.4 0.018 14.8 0.4 12.4 13 0 0 13 13 12 5 zinc-finger C2H2-type FYVE PF01363.21 KFM75927.1 - 0.00092 19.3 74.5 0.31 11.2 7.0 8.0 2 1 6 8 8 7 4 FYVE zinc finger Tox-HNH-HHH PF15637.6 KFM75927.1 - 0.0035 17.5 7.8 24 5.1 0.1 6.3 1 1 5 8 8 8 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Sec23_Sec24 PF04810.15 KFM75927.1 - 0.0043 17.1 55.7 3.8 7.6 0.2 13.8 13 2 2 15 15 15 2 Sec23/Sec24 zinc finger PqqA PF08042.11 KFM75927.1 - 0.0044 17.0 14.6 54 4.0 0.1 9.7 11 0 0 11 11 11 0 PqqA family zf-C2H2_9 PF16293.5 KFM75927.1 - 0.0075 16.1 60.2 8.4 6.3 0.4 13.5 1 1 13 14 14 14 0 C2H2 type zinc-finger (1 copy) zf-Dof PF02701.15 KFM75927.1 - 0.016 15.3 37.2 3.3 7.9 0.3 11.0 1 1 9 10 10 10 0 Dof domain, zinc finger PUF PF00806.19 KFM75927.1 - 0.023 14.4 3.0 99 2.9 0.0 6.0 8 0 0 8 8 6 0 Pumilio-family RNA binding repeat zf-RRPl_C4 PF17026.5 KFM75927.1 - 0.033 14.3 58.2 0.13 12.4 6.8 5.9 1 1 4 5 5 4 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF952 PF06108.12 KFM75927.1 - 0.056 13.5 3.6 1.2e+02 2.8 0.0 5.6 3 3 3 7 7 7 0 Protein of unknown function (DUF952) zinc_ribbon_15 PF17032.5 KFM75927.1 - 0.1 13.3 56.6 3.6 8.4 3.7 7.3 3 2 3 8 8 8 0 zinc-ribbon family tRNA-synt_1_2 PF13603.6 KFM75927.1 - 0.14 11.7 0.0 24 4.3 0.0 3.7 4 1 1 5 5 5 0 Leucyl-tRNA synthetase, Domain 2 Mga PF05043.13 KFM75927.1 - 0.49 11.0 6.5 16 6.1 1.0 4.5 2 2 3 5 5 5 0 Mga helix-turn-helix domain DUF4990 PF16380.5 KFM75927.1 - 1.1 9.3 5.7 1.7e+02 2.3 0.0 5.7 6 1 1 7 7 7 0 Domain of unknown function zf-C2H2_3rep PF18868.1 KFM75927.1 - 5 7.8 56.9 26 5.5 15.7 9.2 3 2 3 6 6 6 0 Zinc finger C2H2-type, 3 repeats DUF2256 PF10013.9 KFM75927.1 - 9.4 6.4 46.8 42 4.4 0.0 12.6 14 0 0 14 14 14 0 Uncharacterized protein conserved in bacteria (DUF2256) DSPn PF14671.6 KFM75928.1 - 5.2e-11 43.2 0.0 5.5e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFM75929.1 - 1.5e-14 54.0 0.0 2.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM75929.1 - 7.1e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM75929.1 - 0.012 15.6 0.3 0.02 14.9 0.3 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM75929.1 - 0.065 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate ANTAR PF03861.14 KFM75929.1 - 0.35 10.8 1.4 1.2 9.0 0.0 2.5 3 0 0 3 3 3 0 ANTAR domain Lig_chan PF00060.26 KFM75931.1 - 1.2e-07 31.7 0.3 1.2e-07 31.6 0.3 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel VASt PF16016.5 KFM75932.1 - 9.9e-36 123.5 0.7 9.9e-36 123.5 0.7 2.7 3 0 0 3 3 3 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KFM75932.1 - 1.7e-23 82.6 0.1 5e-23 81.2 0.1 1.8 1 0 0 1 1 1 1 GRAM domain DUF5641 PF18701.1 KFM75934.1 - 9.4e-17 61.0 1.9 1.3e-16 60.5 1.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) HTH_Tnp_Tc3_2 PF01498.18 KFM75935.1 - 2.4e-19 69.3 3.8 5e-19 68.3 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75935.1 - 3.1e-16 59.4 0.0 1.9e-15 56.9 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM75935.1 - 3.2e-07 30.9 2.0 3.2e-07 30.9 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM75935.1 - 0.00031 20.6 0.6 0.0051 16.7 0.0 2.6 2 1 1 3 3 3 1 MarR family HTH_29 PF13551.6 KFM75935.1 - 0.0011 19.0 0.3 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM75935.1 - 0.0011 19.0 0.8 0.28 11.3 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM75935.1 - 0.0012 18.7 0.3 0.018 15.0 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KFM75935.1 - 0.018 14.8 1.8 1.2 9.1 0.0 3.2 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 KFM75935.1 - 0.032 14.3 0.7 8.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 KFM75935.1 - 0.12 12.6 0.1 19 5.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Malectin PF11721.8 KFM75936.1 - 1e-42 146.1 0.1 1.2e-42 145.8 0.1 1.1 1 0 0 1 1 1 1 Malectin domain Sid-5 PF17204.3 KFM75937.1 - 0.063 13.4 2.0 0.071 13.3 2.0 1.1 1 0 0 1 1 1 0 Sid-5 family BACK PF07707.15 KFM75939.1 - 2.1e-08 34.2 0.0 5.5e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF433 PF04255.14 KFM75940.1 - 0.032 14.1 0.4 0.052 13.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) F-box-like PF12937.7 KFM75942.1 - 1.7e-09 37.4 0.3 3.4e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like XPA_N PF01286.18 KFM75942.1 - 0.0011 18.9 0.1 0.0024 17.9 0.1 1.5 1 0 0 1 1 1 1 XPA protein N-terminal Pox_A14 PF05767.12 KFM75943.1 - 0.031 14.4 0.3 0.035 14.3 0.3 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 zf-H2C2_2 PF13465.6 KFM75944.1 - 1.1e-10 41.4 8.5 5.5e-08 32.9 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM75944.1 - 6.8e-09 35.3 7.2 3.3e-07 29.9 0.5 2.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM75944.1 - 1.9e-07 31.2 10.6 0.0017 18.7 1.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75944.1 - 2e-06 28.1 9.4 0.0071 17.1 1.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75944.1 - 0.00018 21.7 0.7 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM75944.1 - 0.0034 17.7 1.7 0.25 11.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFM75944.1 - 0.0053 17.1 2.1 0.83 10.0 0.5 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_12 PF18658.1 KFM75944.1 - 0.0068 15.9 2.3 0.35 10.5 1.1 2.2 1 1 1 2 2 2 1 Zinc-finger C2H2-type zf-C2HE PF16278.5 KFM75944.1 - 0.01 16.3 2.2 0.68 10.4 0.1 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 KFM75944.1 - 0.049 13.3 3.7 0.71 9.6 0.5 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 KFM75944.1 - 0.05 13.5 0.7 0.05 13.5 0.7 1.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-MYST PF17772.1 KFM75944.1 - 0.054 13.1 0.6 4.4 7.0 0.0 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain ROS_MUCR PF05443.11 KFM75944.1 - 0.21 11.6 1.0 10 6.2 0.1 2.1 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein Sushi PF00084.20 KFM75945.1 - 2.3e-15 56.9 3.9 6.8e-07 29.8 0.9 3.4 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) Lectin_C PF00059.21 KFM75945.1 - 1.2e-05 26.0 0.6 2.8e-05 24.8 0.2 1.8 2 0 0 2 2 2 1 Lectin C-type domain F5_F8_type_C PF00754.25 KFM75945.1 - 0.0048 17.0 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain zf-H2C2_2 PF13465.6 KFM75946.1 - 2.4e-106 343.8 109.9 1e-09 38.4 0.8 15.1 15 0 0 15 15 15 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75946.1 - 7.9e-78 252.8 116.6 2.7e-06 27.5 0.8 14.1 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-met PF12874.7 KFM75946.1 - 6.6e-55 182.0 107.2 4.2e-05 23.8 1.2 14.2 14 0 0 14 14 14 14 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM75946.1 - 1.6e-54 177.8 107.9 0.00026 21.6 1.5 14.1 14 0 0 14 14 14 14 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75946.1 - 1.5e-25 88.9 84.3 0.019 15.3 0.9 14.4 14 0 0 14 14 14 12 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM75946.1 - 1.4e-21 76.0 70.5 0.0036 17.0 0.0 14.0 14 0 0 14 14 14 8 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM75946.1 - 1.8e-21 75.6 100.4 0.018 15.0 0.6 14.9 14 1 0 14 14 14 11 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM75946.1 - 1e-14 54.3 48.6 0.2 11.7 0.1 13.9 6 6 8 14 14 14 4 Sec23/Sec24 zinc finger BolA PF01722.18 KFM75946.1 - 1.1e-14 54.4 20.6 0.085 13.1 0.3 9.8 1 1 6 9 9 9 3 BolA-like protein zf-C2HC_2 PF13913.6 KFM75946.1 - 1.6e-12 46.9 58.3 0.78 9.7 0.5 14.3 14 0 0 14 14 14 5 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFM75946.1 - 9.9e-11 41.2 96.1 0.22 11.3 2.4 14.3 14 0 0 14 14 14 8 C2H2-type zinc-finger domain zf-DBF PF07535.12 KFM75946.1 - 4e-10 39.6 69.9 4.3 7.5 0.4 14.2 14 0 0 14 14 14 3 DBF zinc finger zf-C2H2_9 PF16293.5 KFM75946.1 - 1.3e-06 28.2 65.3 1.7 8.5 0.1 13.7 2 2 12 14 14 14 3 C2H2 type zinc-finger (1 copy) C1_4 PF07975.12 KFM75946.1 - 3.7e-06 27.1 69.8 0.022 15.0 1.6 9.1 3 2 8 11 11 11 4 TFIIH C1-like domain DUF2256 PF10013.9 KFM75946.1 - 9.5e-06 25.6 57.1 4.4 7.5 0.1 13.8 14 0 0 14 14 14 1 Uncharacterized protein conserved in bacteria (DUF2256) Zf_RING PF16744.5 KFM75946.1 - 1e-05 25.6 65.4 8.5 6.6 0.1 13.4 1 1 11 12 12 12 0 KIAA1045 RING finger GAGA PF09237.11 KFM75946.1 - 1.4e-05 24.8 24.8 2.8 7.8 0.0 9.7 2 2 9 12 12 12 1 GAGA factor Yop-YscD_ppl PF16693.5 KFM75946.1 - 0.00018 21.1 0.0 0.27 10.6 0.0 3.7 2 2 1 4 4 4 1 Inner membrane component of T3SS, periplasmic domain zinc_ribbon_15 PF17032.5 KFM75946.1 - 0.0003 21.5 63.0 0.58 10.9 1.6 7.6 1 1 6 8 8 8 3 zinc-ribbon family Baculo_IE-1 PF05290.11 KFM75946.1 - 0.00089 19.2 52.0 1.3 8.9 3.9 10.9 1 1 5 6 6 6 1 Baculovirus immediate-early protein (IE-0) zf-MYST PF17772.1 KFM75946.1 - 0.0029 17.2 78.7 0.31 10.7 0.3 13.6 4 3 10 14 14 14 3 MYST family zinc finger domain zinc-ribbons_6 PF07191.12 KFM75946.1 - 0.0035 17.3 61.2 2 8.4 1.4 10.5 1 1 9 10 10 9 2 zinc-ribbons zf-RRPl_C4 PF17026.5 KFM75946.1 - 0.0056 16.8 66.0 0.037 14.1 6.6 6.3 1 1 8 9 9 9 5 Putative ribonucleoprotein zinc-finger pf C4 type Complex1_49kDa PF00346.19 KFM75946.1 - 0.051 12.7 11.5 1.8 7.6 0.2 3.9 1 1 3 4 4 4 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-C2H2_8 PF15909.5 KFM75946.1 - 0.3 11.4 63.2 0.12 12.7 2.8 7.3 1 1 5 7 7 7 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFM75946.1 - 0.35 11.2 104.6 1.6 9.1 0.3 13.7 1 1 12 13 13 13 0 C2H2 type zinc-finger (2 copies) zf-RING_UBOX PF13445.6 KFM75946.1 - 0.37 10.9 29.1 1.1e+02 2.9 1.3 11.6 13 1 0 13 13 13 0 RING-type zinc-finger Zn-ribbon_8 PF09723.10 KFM75946.1 - 0.52 10.5 56.6 3 8.0 2.3 9.6 3 3 10 13 13 13 0 Zinc ribbon domain DUF4499 PF14934.6 KFM75946.1 - 6.1 7.3 15.0 95 3.4 0.0 7.1 4 3 6 10 10 8 0 Domain of unknown function (DUF4499) M-factor PF03855.13 KFM75946.1 - 7.6 6.8 8.9 2.2e+02 2.1 0.1 5.7 5 0 0 5 5 5 0 M-factor zf_UBZ PF18439.1 KFM75946.1 - 9.6 5.9 60.5 4.4 7.0 0.1 13.4 14 0 0 14 14 14 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KFM75947.1 - 4.7e-48 159.6 56.6 5.9e-09 36.0 3.4 8.4 8 1 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75947.1 - 1.1e-29 101.2 68.3 1.5e-05 25.1 0.6 8.0 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75947.1 - 2.2e-23 80.9 65.5 0.00025 21.6 0.6 8.0 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.7 KFM75947.1 - 1.7e-12 47.3 57.7 0.00075 19.8 1.8 8.2 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM75947.1 - 1.4e-09 37.6 35.9 0.0028 17.4 0.2 7.9 7 1 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM75947.1 - 2.5e-08 33.7 54.6 0.0024 17.8 0.5 9.2 8 2 1 9 9 9 4 C2H2-type zinc finger Zf_RING PF16744.5 KFM75947.1 - 0.00041 20.4 31.8 0.092 12.9 0.8 6.3 1 1 5 6 6 6 2 KIAA1045 RING finger BHD_1 PF10403.9 KFM75947.1 - 0.00083 19.1 0.5 7.8 6.4 0.0 3.7 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 1 Baculo_IE-1 PF05290.11 KFM75947.1 - 0.0015 18.5 18.5 0.58 10.1 1.9 4.1 1 1 3 4 4 4 2 Baculovirus immediate-early protein (IE-0) BolA PF01722.18 KFM75947.1 - 0.0023 18.2 6.1 1.8 8.9 0.8 5.1 1 1 2 3 3 3 1 BolA-like protein zf-C2H2_11 PF16622.5 KFM75947.1 - 0.0025 17.5 2.4 0.0025 17.5 2.4 6.9 7 0 0 7 7 7 2 zinc-finger C2H2-type FYVE PF01363.21 KFM75947.1 - 0.012 15.7 40.9 0.013 15.6 8.2 4.6 1 1 3 4 4 4 0 FYVE zinc finger C1_1 PF00130.22 KFM75947.1 - 0.035 14.0 39.6 0.75 9.7 6.9 6.0 1 1 4 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 KFM75947.1 - 0.067 13.1 31.7 0.3 11.1 0.2 7.4 8 0 0 8 8 7 0 zinc-finger of a C2HC-type zf_C2H2_13 PF18508.1 KFM75947.1 - 0.29 10.7 0.2 0.29 10.7 0.2 3.6 2 1 1 3 3 3 0 Zinc finger domain zf-CHCC PF10276.9 KFM75947.1 - 0.29 11.2 13.4 2.3 8.3 0.1 5.0 6 0 0 6 6 6 0 Zinc-finger domain zinc_ribbon_15 PF17032.5 KFM75947.1 - 0.41 11.4 26.0 0.32 11.8 1.3 4.1 1 1 5 6 6 6 0 zinc-ribbon family DUF2256 PF10013.9 KFM75947.1 - 0.42 10.8 24.6 9.8 6.4 0.1 7.0 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_jaz PF12171.8 KFM75947.1 - 0.99 9.8 0.1 0.88 9.9 1.9 7.7 6 2 2 8 8 8 0 Zinc-finger double-stranded RNA-binding Thioredoxin_16 PF18569.1 KFM75947.1 - 2.2 8.4 8.9 14 5.8 0.5 3.8 1 1 3 4 4 4 0 Thioredoxin-like domain YyzF PF14116.6 KFM75947.1 - 2.8 8.0 18.2 17 5.6 0.1 6.4 7 0 0 7 7 7 0 YyzF-like protein zf-Sec23_Sec24 PF04810.15 KFM75947.1 - 3.5 7.8 17.1 15 5.7 0.2 5.8 7 0 0 7 7 6 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.10 KFM75947.1 - 3.7 7.8 26.3 1.8 8.8 2.5 5.0 2 2 3 5 5 5 0 Zinc ribbon domain Cript PF10235.9 KFM75947.1 - 5 7.8 32.8 0.23 12.1 3.8 4.6 1 1 2 4 4 3 0 Microtubule-associated protein CRIPT C5HCH PF17982.1 KFM75947.1 - 7.1 6.9 39.5 2.8 8.1 1.1 7.7 5 2 3 8 8 8 0 NSD Cys-His rich domain HTH_Tnp_Tc3_2 PF01498.18 KFM75948.1 - 2e-16 60.0 2.2 4.2e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75948.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 KFM75949.1 - 1.3e-76 258.2 0.0 1.7e-76 257.8 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM75949.1 - 0.02 14.6 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 KFM75949.1 - 0.035 14.1 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Zot PF05707.12 KFM75949.1 - 0.079 12.6 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) HTH_Tnp_Tc3_2 PF01498.18 KFM75950.1 - 5.6e-16 58.6 3.5 6.1e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75950.1 - 1.4e-13 50.8 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75950.1 - 2.3e-07 30.4 1.2 7.4e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75950.1 - 0.0029 17.3 0.6 0.008 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75950.1 - 2.8 8.6 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM75951.1 - 4.7e-16 58.8 3.5 6.2e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75951.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM75951.1 - 3.1e-07 30.0 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM75951.1 - 0.0029 17.4 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM75951.1 - 2.9 8.6 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Glyco_hydro_31 PF01055.26 KFM75952.1 - 2.1e-31 109.6 0.1 2.8e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFM75952.1 - 2.6e-19 69.5 0.7 3.9e-19 69.0 0.7 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 KFM75952.1 - 5.7e-12 45.3 5.0 1e-11 44.5 5.0 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 KFM75952.1 - 7.5e-08 32.6 4.6 3.2e-07 30.6 0.2 3.2 4 0 0 4 4 4 1 Galactose mutarotase-like Fcf1 PF04900.12 KFM75952.1 - 0.055 13.9 0.1 0.092 13.2 0.1 1.3 1 0 0 1 1 1 0 Fcf1 ANAPC4_WD40 PF12894.7 KFM75954.1 - 0.0022 18.2 0.0 0.016 15.5 0.0 2.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM75954.1 - 0.02 15.8 1.1 0.084 13.8 1.1 2.0 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1487 PF07368.11 KFM75955.1 - 0.065 12.7 0.1 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) KxDL PF10241.9 KFM75955.1 - 2.4 8.5 10.9 0.7 10.2 1.2 3.7 2 2 2 4 4 4 0 Uncharacterized conserved protein OTU PF02338.19 KFM75956.1 - 0.0027 18.2 0.0 0.0083 16.6 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4619 PF15398.6 KFM75957.1 - 0.018 14.6 1.0 0.018 14.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4619) Peptidase_M28 PF04389.17 KFM75958.1 - 7.8e-40 136.7 0.0 3.5e-39 134.6 0.0 2.0 2 1 0 2 2 2 1 Peptidase family M28 Nicastrin PF05450.15 KFM75958.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Nicastrin PriCT_2 PF08707.11 KFM75958.1 - 0.0089 16.4 0.5 0.032 14.6 0.1 2.1 2 0 0 2 2 2 1 Primase C terminal 2 (PriCT-2) Herpes_MCP PF03122.14 KFM75958.1 - 0.088 10.3 0.0 0.12 9.8 0.0 1.1 1 0 0 1 1 1 0 Herpes virus major capsid protein Spectrin PF00435.21 KFM75959.1 - 0 1164.2 234.8 4.5e-23 81.7 6.1 20.2 20 0 0 20 20 20 20 Spectrin repeat PH_9 PF15410.6 KFM75959.1 - 1.8e-18 67.0 0.1 1.1e-17 64.4 0.1 2.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFM75959.1 - 7.1e-10 39.3 0.4 4.2e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 PH domain ASCH PF04266.14 KFM75959.1 - 0.063 13.9 2.4 11 6.6 0.0 4.7 4 0 0 4 4 4 0 ASCH domain BTB PF00651.31 KFM75960.1 - 3.4e-19 69.1 1.0 6.6e-18 65.0 0.1 2.6 1 1 2 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFM75960.1 - 4.6e-08 33.1 0.2 1.5e-06 28.2 0.0 2.8 2 1 1 3 3 3 1 BTB And C-terminal Kelch Rota_NS35 PF02509.14 KFM75960.1 - 0.066 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 DUF4817 PF16087.5 KFM75961.1 - 1.9e-10 40.4 0.0 3.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 KFM75961.1 - 0.00011 22.8 0.2 0.0003 21.3 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM75961.1 - 0.00017 21.3 0.6 0.025 14.4 0.1 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM75961.1 - 0.01 15.9 0.1 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM75961.1 - 0.03 14.4 0.2 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix DUF1593 PF07632.11 KFM75961.1 - 0.042 13.3 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) Peptidase_C78 PF07910.13 KFM75962.1 - 1.6e-62 210.8 0.0 2.6e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 KFM75962.1 - 8.8e-10 38.7 17.2 0.0035 17.6 0.1 5.4 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFM75962.1 - 8.5e-06 26.2 24.1 0.28 12.1 0.1 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM75962.1 - 7.4e-05 22.9 6.5 0.15 12.4 0.0 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM75962.1 - 0.0085 15.8 0.5 0.0085 15.8 0.5 2.8 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM75962.1 - 0.009 16.4 21.5 0.46 11.0 0.1 5.5 5 0 0 5 5 5 2 Zinc finger, C2H2 type Peptidase_C54 PF03416.19 KFM75962.1 - 0.012 15.0 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C54 DUF629 PF04780.12 KFM75962.1 - 0.12 10.9 7.3 8.4 4.8 0.0 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 KFM75962.1 - 0.12 12.7 11.9 2.3 8.6 0.0 4.9 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Vps36-NZF-N PF16988.5 KFM75962.1 - 0.95 8.9 5.1 2.7 7.4 0.0 3.3 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_9 PF16293.5 KFM75962.1 - 9.2 6.2 17.2 7.9 6.4 0.0 4.3 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) Mito_carr PF00153.27 KFM75963.1 - 1.1e-66 220.8 2.2 6.7e-22 77.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM75963.1 - 0.033 13.3 0.1 2.7 7.1 0.0 2.6 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Hemocyanin_M PF00372.19 KFM75964.1 - 3e-74 249.6 0.0 4.2e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Hemocyanin_C PF03723.14 KFM75964.1 - 1.7e-68 230.6 0.0 2.2e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_N PF03722.14 KFM75964.1 - 6.2e-17 62.3 0.0 1.4e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 Hemocyanin, all-alpha domain Tyrosinase PF00264.20 KFM75964.1 - 1.2e-07 32.2 0.8 1.8e-07 31.7 0.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase PA26 PF04636.13 KFM75965.1 - 4.1e-133 444.5 19.3 5.1e-132 440.9 19.3 2.0 1 1 0 1 1 1 1 PA26 p53-induced protein (sestrin) CAP PF00188.26 KFM75966.1 - 2e-16 60.9 2.5 2e-16 60.9 2.5 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Cullin PF00888.22 KFM75968.1 - 1.2e-197 658.4 17.6 1.2e-197 658.4 17.6 1.6 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KFM75968.1 - 1e-27 96.0 4.2 1e-27 96.0 4.2 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain Phage_TAC_12 PF12363.8 KFM75968.1 - 0.01 16.2 0.2 0.038 14.4 0.1 2.1 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC HflK_N PF12221.8 KFM75968.1 - 0.18 11.9 0.4 0.95 9.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial membrane protein N terminal zf-CCHC PF00098.23 KFM75969.1 - 6.7e-50 165.0 67.7 2.2e-08 33.8 2.7 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KFM75969.1 - 1.7e-13 50.0 48.9 0.0031 17.2 0.7 7.1 4 2 3 7 7 7 7 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM75969.1 - 9.8e-13 47.6 43.7 0.033 13.9 1.0 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KFM75969.1 - 2e-06 27.7 39.5 0.044 13.7 0.9 7.0 2 1 5 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.6 KFM75969.1 - 0.015 15.1 1.3 0.015 15.1 1.3 6.6 7 0 0 7 7 7 0 Zinc knuckle DUF3878 PF12994.7 KFM75969.1 - 0.055 12.9 0.8 5.4 6.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3878) WD40 PF00400.32 KFM75971.1 - 2.1e-17 63.1 2.6 1.6e-06 28.8 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM75971.1 - 9.4e-15 54.7 0.0 4.1e-06 27.0 0.0 4.1 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Arylsulfotran_2 PF14269.6 KFM75971.1 - 0.0012 18.3 0.6 0.0019 17.6 0.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Frtz PF11768.8 KFM75971.1 - 0.0015 17.0 0.0 0.097 11.0 0.0 2.2 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KFM75971.1 - 0.023 14.0 0.6 0.12 11.6 0.3 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF2415 PF10313.9 KFM75971.1 - 0.027 14.4 0.1 0.34 10.9 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) PD40 PF07676.12 KFM75971.1 - 0.035 14.1 0.4 2.3 8.3 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PUB PF09409.10 KFM75972.1 - 3.7e-26 90.9 2.2 4.8e-26 90.5 0.8 1.9 2 0 0 2 2 2 1 PUB domain UBX PF00789.20 KFM75972.1 - 2.8e-07 30.7 0.1 6.4e-06 26.3 0.0 2.5 1 1 1 2 2 2 1 UBX domain Mon1 PF03164.14 KFM75973.1 - 4.7e-145 483.7 1.6 5.6e-145 483.4 1.6 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Pkinase_fungal PF17667.1 KFM75973.1 - 0.018 13.8 0.1 0.025 13.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase DAG1 PF05454.11 KFM75974.1 - 4.4e-86 288.9 12.9 2.6e-70 237.1 10.0 2.2 2 0 0 2 2 2 2 Dystroglycan (Dystrophin-associated glycoprotein 1) a_DG1_N2 PF18424.1 KFM75974.1 - 5.3e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Alpha-Dystroglycan N-terminal domain 2 TMEM154 PF15102.6 KFM75974.1 - 0.0037 17.2 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family Sarcoglycan_2 PF05510.13 KFM75974.1 - 0.015 14.1 0.0 0.031 13.1 0.0 1.5 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF4625 PF15418.6 KFM75974.1 - 0.027 14.7 0.0 0.46 10.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) PA14 PF07691.12 KFM75974.1 - 0.038 13.8 1.2 6.6 6.5 0.0 3.6 3 1 1 4 4 4 0 PA14 domain RCR PF12273.8 KFM75974.1 - 0.052 14.2 3.3 0.058 14.0 1.3 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.10 KFM75974.1 - 1.2 8.6 4.2 2.5 7.6 4.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DDE_3 PF13358.6 KFM75976.1 - 2.9e-16 59.5 0.1 3.1e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75976.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75978.1 - 2.6e-14 53.2 0.1 2.3e-13 50.1 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM75978.1 - 2.1e-10 40.7 1.0 4e-10 39.8 1.0 1.5 1 0 0 1 1 1 1 Transposase zf-RING_4 PF14570.6 KFM75978.1 - 0.081 12.7 1.5 0.15 11.9 1.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM75979.1 - 4.6e-16 58.8 2.2 4.6e-16 58.8 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM75979.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease AF-4 PF05110.13 KFM75980.1 - 0.00057 18.1 0.0 0.00057 18.1 0.0 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein HTH_Tnp_Tc3_2 PF01498.18 KFM75981.1 - 1.7e-17 63.4 1.4 4e-17 62.2 1.4 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75981.1 - 2.7e-14 53.2 0.0 4.4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM75981.1 - 0.00029 21.4 8.8 0.0003 21.3 1.5 2.8 3 0 0 3 3 3 1 Homeodomain-like domain AF-4 PF05110.13 KFM75982.1 - 1.7e-26 92.7 4.1 2e-26 92.5 4.1 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Aida_N PF08910.10 KFM75982.1 - 0.024 15.0 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 Aida N-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM75983.1 - 2.3e-08 34.1 0.7 6.3e-08 32.8 0.4 1.8 2 0 0 2 2 2 1 Transposase HTH_IclR PF09339.10 KFM75983.1 - 9e-06 25.4 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KFM75983.1 - 0.00021 21.0 0.9 0.00076 19.2 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM75983.1 - 0.0059 16.5 0.2 0.0059 16.5 0.2 1.9 3 0 0 3 3 3 1 MarR family HTH_28 PF13518.6 KFM75983.1 - 0.0096 16.0 2.0 0.015 15.4 1.2 1.8 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM75983.1 - 0.015 15.3 1.3 0.033 14.2 1.3 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 KFM75983.1 - 0.021 15.4 5.5 0.42 11.2 1.6 2.7 1 1 2 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 KFM75983.1 - 0.024 14.4 0.0 0.076 12.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 KFM75983.1 - 1.9 8.9 11.0 0.28 11.6 4.2 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM75985.1 - 2.6e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM75985.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ras PF00071.22 KFM75986.1 - 1.1e-55 187.6 0.4 2.1e-55 186.8 0.4 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM75986.1 - 2e-35 121.6 0.2 5.2e-35 120.3 0.2 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM75986.1 - 2.7e-19 69.3 0.0 8.4e-19 67.7 0.0 1.9 1 0 0 1 1 1 1 ADP-ribosylation factor family EF-hand_7 PF13499.6 KFM75986.1 - 9.3e-09 35.6 0.2 9.3e-09 35.6 0.2 2.9 3 0 0 3 3 2 1 EF-hand domain pair Gtr1_RagA PF04670.12 KFM75986.1 - 1.1e-08 34.8 0.1 1.1e-08 34.8 0.1 2.4 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM75986.1 - 1.4e-07 31.6 2.6 2.3e-07 30.9 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KFM75986.1 - 1.4e-07 30.5 2.0 0.00018 20.8 0.6 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM75986.1 - 8e-07 28.5 1.8 0.0032 17.3 0.7 2.9 2 0 0 2 2 2 2 EF-hand domain SRPRB PF09439.10 KFM75986.1 - 1.7e-06 27.6 0.1 1.7e-06 27.6 0.1 2.8 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit EF-hand_8 PF13833.6 KFM75986.1 - 7.1e-06 25.8 0.1 0.00017 21.4 0.1 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM75986.1 - 1e-05 24.8 0.8 4.3e-05 22.8 0.8 2.1 1 0 0 1 1 1 1 EF hand GTP_EFTU PF00009.27 KFM75986.1 - 1.1e-05 25.1 0.1 1.1e-05 25.1 0.1 2.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM75986.1 - 0.00011 22.2 2.9 0.1 12.5 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase PduV-EutP PF10662.9 KFM75986.1 - 0.018 14.8 0.0 0.064 13.0 0.0 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFM75986.1 - 0.037 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KFM75986.1 - 0.091 13.2 1.6 0.61 10.5 0.0 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Tweety PF04906.13 KFM75986.1 - 1.6 7.3 5.1 9.6 4.7 1.3 2.8 2 1 2 4 4 4 0 Tweety ABC_tran PF00005.27 KFM75986.1 - 2.9 8.4 0.0 2.9 8.4 0.0 3.4 2 1 0 2 2 1 0 ABC transporter AAA_22 PF13401.6 KFM75986.1 - 5.2 7.3 6.8 6.3 7.1 0.0 3.6 2 2 1 3 3 3 0 AAA domain DDE_Tnp_1 PF01609.21 KFM75986.1 - 7.2 6.2 7.3 46 3.6 7.3 2.3 1 1 0 1 1 1 0 Transposase DDE domain AAA PF00004.29 KFM75987.1 - 2e-40 138.3 0.0 4.8e-40 137.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM75987.1 - 7.7e-14 51.2 0.8 8.1e-13 47.9 0.1 2.6 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 KFM75987.1 - 4.9e-11 42.4 0.2 5.3e-10 39.2 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KFM75987.1 - 1.1e-05 25.2 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFM75987.1 - 4.9e-05 23.5 0.7 0.00012 22.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFM75987.1 - 9.2e-05 22.6 0.0 9.2e-05 22.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KFM75987.1 - 0.0003 20.8 0.2 0.0017 18.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM75987.1 - 0.00069 20.0 0.5 0.0071 16.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KFM75987.1 - 0.00074 19.0 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KFM75987.1 - 0.00095 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KFM75987.1 - 0.0016 18.7 0.4 0.035 14.4 0.4 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFM75987.1 - 0.0017 18.4 0.0 0.0068 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFM75987.1 - 0.0031 17.3 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KFM75987.1 - 0.0035 16.9 0.2 0.0078 15.7 0.2 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 KFM75987.1 - 0.0036 17.3 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KFM75987.1 - 0.011 16.0 0.4 0.24 11.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFM75987.1 - 0.015 15.1 0.3 0.056 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFM75987.1 - 0.015 14.6 0.2 2.5 7.4 0.1 2.4 1 1 1 2 2 2 0 KaiC NACHT PF05729.12 KFM75987.1 - 0.021 14.7 0.1 0.069 13.1 0.1 1.8 1 1 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.21 KFM75987.1 - 0.026 14.2 0.0 0.17 11.5 0.0 2.3 3 0 0 3 3 2 0 Guanylate kinase CHASE3 PF05227.13 KFM75987.1 - 0.05 13.5 1.4 0.11 12.4 1.4 1.5 1 0 0 1 1 1 0 CHASE3 domain PhoH PF02562.16 KFM75987.1 - 0.051 13.0 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KFM75987.1 - 0.057 13.8 0.1 0.15 12.4 0.1 1.9 1 1 0 1 1 1 0 RNA helicase MIT PF04212.18 KFM75987.1 - 0.068 13.2 0.2 0.068 13.2 0.2 2.7 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain MHCassoc_trimer PF08831.10 KFM75987.1 - 0.08 13.0 0.5 0.25 11.4 0.1 2.0 2 0 0 2 2 1 0 Class II MHC-associated invariant chain trimerisation domain AAA_18 PF13238.6 KFM75987.1 - 0.087 13.4 0.0 0.087 13.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KFM75987.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFM75987.1 - 0.11 12.2 0.0 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 KFM75987.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KFM75987.1 - 0.17 11.5 0.3 0.61 9.6 0.3 1.9 1 1 1 2 2 2 0 AAA domain TPR_2 PF07719.17 KFM75987.1 - 0.27 11.4 3.7 10 6.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat FAM176 PF14851.6 KFM75987.1 - 0.57 9.8 3.0 1.4 8.6 3.0 1.6 1 0 0 1 1 1 0 FAM176 family AAA_11 PF13086.6 KFM75987.1 - 0.6 9.9 6.9 1.1 9.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain TPR_8 PF13181.6 KFM75987.1 - 1.8 9.0 4.3 37 4.9 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NDUF_B12 PF08122.12 KFM75988.1 - 0.17 12.0 6.8 1.8 8.6 1.6 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Glyco_hydro_15 PF00723.21 KFM75989.1 - 2.2e-160 534.4 0.0 2.7e-160 534.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF2185 PF09951.9 KFM75989.1 - 0.15 11.9 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) UcrQ PF02939.16 KFM75990.1 - 5.9e-35 119.1 0.1 6.5e-35 118.9 0.1 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 KFM75990.1 - 0.0013 19.1 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 NTF2 PF02136.20 KFM75991.1 - 2.7e-16 60.2 0.0 3e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KFM75991.1 - 0.00057 19.9 0.0 0.00071 19.5 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 WGG PF10273.9 KFM75992.1 - 0.019 15.6 0.0 0.03 15.0 0.0 1.3 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 HSP70 PF00012.20 KFM75993.1 - 7e-251 833.6 10.3 7.9e-251 833.5 10.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM75993.1 - 7.7e-18 64.4 2.2 1.3e-16 60.3 0.6 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFM75993.1 - 7e-05 23.2 4.4 0.087 13.2 0.1 3.6 3 2 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 KFM75993.1 - 0.0024 16.9 0.5 0.0061 15.6 0.5 1.6 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain DUF4624 PF15417.6 KFM75993.1 - 0.0064 16.3 0.3 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4624) FGGY_C PF02782.16 KFM75993.1 - 0.0094 15.7 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KFM75993.1 - 0.013 14.8 2.2 0.015 14.5 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Phage_sheath_1N PF17481.2 KFM75993.1 - 1.5 9.3 5.9 2.7 8.5 0.2 3.2 3 1 0 3 3 3 0 Phage tail sheath protein beta-sandwich domain Lyase_1 PF00206.20 KFM75994.1 - 0.0031 16.9 0.5 0.0048 16.3 0.5 1.2 1 0 0 1 1 1 1 Lyase Baculo_PEP_C PF04513.12 KFM75994.1 - 0.0038 17.3 0.6 0.0096 16.0 0.4 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus KTI12 PF08433.10 KFM75994.1 - 0.022 14.2 2.6 0.034 13.6 1.6 1.7 1 1 1 2 2 2 0 Chromatin associated protein KTI12 DUF3882 PF07066.11 KFM75994.1 - 0.081 13.0 0.1 0.19 11.8 0.0 1.7 1 1 1 2 2 2 0 Lactococcus phage M3 protein DUF1848 PF08902.11 KFM75994.1 - 0.12 12.1 1.2 0.19 11.4 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) HJURP_mid PF12346.8 KFM75994.1 - 0.52 10.8 5.9 2.7 8.5 5.9 2.2 1 1 0 1 1 1 0 Holliday junction recognition protein-associated repeat NPV_P10 PF05531.12 KFM75994.1 - 1.1 9.8 6.7 1.3 9.6 4.7 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 KFM75994.1 - 3.5 7.6 8.0 0.25 11.3 1.6 2.3 2 1 0 2 2 2 0 Laminin Domain II I-set PF07679.16 KFM75995.1 - 2e-26 91.9 0.1 3e-18 65.6 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM75995.1 - 3.4e-23 82.0 0.9 1.2e-14 54.6 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFM75995.1 - 1.3e-15 57.3 0.0 7.9e-10 38.8 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFM75995.1 - 9.3e-15 54.7 0.3 1.5e-06 28.4 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain fn3 PF00041.21 KFM75995.1 - 7.6e-10 39.0 0.8 1.7e-09 37.9 0.8 1.5 1 0 0 1 1 1 1 Fibronectin type III domain V-set PF07686.17 KFM75995.1 - 6e-08 32.8 0.1 0.045 13.9 0.1 3.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFM75995.1 - 3.3e-06 27.6 2.2 6e-06 26.7 1.7 1.7 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFM75995.1 - 0.00011 22.2 0.0 0.59 10.2 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM75995.1 - 0.0004 20.7 0.0 0.93 9.9 0.0 3.0 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain I-set PF07679.16 KFM75996.1 - 0.00014 21.8 0.0 0.00016 21.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM75996.1 - 0.0058 17.2 0.0 0.0058 17.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Adenylsucc_synt PF00709.21 KFM75997.1 - 1.4e-141 472.2 0.4 1.6e-141 472.1 0.4 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Zeta_toxin PF06414.12 KFM75997.1 - 0.057 12.7 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Methyltransf_14 PF08484.11 KFM75997.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain zf-H2C2_2 PF13465.6 KFM75998.1 - 1.3e-88 287.8 92.4 1.4e-09 37.9 0.2 13.9 14 0 0 14 14 13 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM75998.1 - 1.1e-60 198.8 131.9 5.4e-06 26.6 4.7 13.1 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM75998.1 - 2.7e-39 130.4 120.2 0.0021 18.7 0.6 13.1 13 0 0 13 13 13 13 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM75998.1 - 1.2e-36 124.0 96.1 0.00062 19.7 0.6 13.4 13 0 0 13 13 13 12 C2H2-type zinc finger zf-met PF12874.7 KFM75998.1 - 8e-26 89.6 101.8 0.00049 20.4 1.1 13.3 13 0 0 13 13 13 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM75998.1 - 7.3e-18 64.4 76.2 0.015 15.5 1.0 13.3 13 0 0 13 13 13 9 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM75998.1 - 8.8e-09 35.2 53.1 0.023 14.7 1.3 9.5 5 2 6 11 11 11 5 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 KFM75998.1 - 1.4e-06 28.1 47.5 0.52 10.3 0.7 12.5 12 1 1 13 13 13 2 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 KFM75998.1 - 9e-05 22.0 54.2 0.46 10.1 1.2 11.9 13 0 0 13 13 13 4 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 KFM75998.1 - 0.00012 21.9 73.7 0.9 9.5 2.0 12.0 3 2 7 11 11 11 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KFM75998.1 - 0.00014 21.9 43.8 0.51 10.5 2.2 8.6 5 2 6 11 11 11 4 Zinc ribbon domain zf-RRPl_C4 PF17026.5 KFM75998.1 - 0.00029 20.9 45.6 0.21 11.7 4.7 5.7 1 1 5 6 6 6 5 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFM75998.1 - 0.00029 21.5 48.4 2.2 9.1 1.2 6.9 1 1 7 8 8 8 5 zinc-ribbon family FAM83 PF07894.12 KFM75998.1 - 0.00045 19.8 10.3 0.013 15.1 0.7 3.2 1 1 1 3 3 3 2 FAM83 A-H DUF2256 PF10013.9 KFM75998.1 - 0.00066 19.7 42.5 6.8 6.9 0.0 12.4 13 0 0 13 13 13 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFM75998.1 - 0.0048 16.8 57.5 1.2 9.1 0.8 12.4 13 0 0 13 13 13 3 zinc-finger of a C2HC-type DUF4712 PF15830.5 KFM75998.1 - 0.008 15.9 1.2 0.82 9.3 0.0 3.2 1 1 2 4 4 4 2 Domain of unknown function (DUF4712) zf_ZIC PF18366.1 KFM75998.1 - 0.025 14.7 1.3 0.025 14.7 1.3 12.2 1 1 12 13 13 13 0 Zic proteins zinc finger domain Ring_hydroxyl_B PF00866.18 KFM75998.1 - 0.15 12.1 0.1 37 4.4 0.0 3.0 3 1 1 4 4 4 0 Ring hydroxylating beta subunit C5HCH PF17982.1 KFM75998.1 - 0.4 10.9 64.6 13 6.1 0.5 12.3 9 3 4 13 13 13 0 NSD Cys-His rich domain DUF3268 PF11672.8 KFM75998.1 - 0.5 10.7 35.6 7.6 6.9 0.2 6.6 3 1 5 9 9 9 0 zinc-finger-containing domain GAGA PF09237.11 KFM75998.1 - 1.2 9.0 25.6 0.45 10.4 0.1 6.8 1 1 6 9 9 9 0 GAGA factor HNH_5 PF14279.6 KFM75998.1 - 1.3 8.9 58.8 13 5.7 0.3 12.0 8 4 2 10 10 10 0 HNH endonuclease zf-CHCC PF10276.9 KFM75998.1 - 1.6 8.8 25.4 10 6.2 0.0 9.6 12 0 0 12 12 12 0 Zinc-finger domain Ribosomal_L15e PF00827.17 KFM76000.1 - 1.2e-95 318.6 8.9 1.4e-95 318.5 8.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Suppressor_APC PF11414.8 KFM76000.1 - 0.074 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DUF2117 PF09890.9 KFM76000.1 - 0.089 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) Nsp1_C PF05064.13 KFM76001.1 - 1.7e-33 114.9 5.5 2.7e-33 114.2 5.5 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG2 PF15967.5 KFM76001.1 - 0.0003 19.5 65.2 0.0003 19.5 65.2 4.1 1 1 3 4 4 4 2 Nucleoporin FG repeated region DDE_3 PF13358.6 KFM76003.1 - 6.9e-16 58.3 0.1 5.7e-15 55.4 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76003.1 - 2e-10 40.8 1.0 4e-10 39.8 1.0 1.5 1 0 0 1 1 1 1 Transposase Na_H_Exchanger PF00999.21 KFM76003.1 - 1.3e-06 27.5 2.3 1.8e-06 27.0 2.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DDE_1 PF03184.19 KFM76004.1 - 1.1e-17 64.2 0.1 2.6e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM76004.1 - 5.3e-05 23.2 0.1 0.00013 21.9 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain ubiquitin PF00240.23 KFM76005.1 - 2e-22 78.7 0.8 3.2e-22 78.0 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFM76005.1 - 1.5e-06 27.9 1.9 2.6e-06 27.2 1.9 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KFM76005.1 - 0.003 17.6 0.3 0.003 17.6 0.3 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFM76005.1 - 0.0033 18.0 1.1 0.012 16.2 1.1 1.9 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KFM76005.1 - 0.012 15.6 2.0 0.62 10.2 0.3 2.5 1 1 1 2 2 2 0 Ubiquitin-like domain UBA PF00627.31 KFM76005.1 - 0.028 14.3 0.2 0.052 13.5 0.2 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Ubiquitin_2 PF14560.6 KFM76005.1 - 0.14 12.7 0.2 0.14 12.7 0.2 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain DUF908 PF06012.12 KFM76005.1 - 1.3 8.3 7.8 1.6 8.1 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 KFM76005.1 - 1.6 7.4 4.8 1.7 7.3 4.8 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KFM76005.1 - 5.2 6.2 6.9 7 5.8 6.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter XPC-binding PF09280.11 KFM76006.1 - 1.4e-19 69.6 13.5 2.2e-19 68.9 13.5 1.3 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KFM76006.1 - 8.1e-14 51.2 0.1 1.7e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain N_formyltrans_C PF18216.1 KFM76006.1 - 0.12 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain DUF3760 PF12586.8 KFM76007.1 - 0.0016 18.6 0.2 0.0042 17.2 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3760) Viral_env_E26 PF11050.8 KFM76007.1 - 0.01 15.2 0.3 0.011 15.1 0.3 1.1 1 0 0 1 1 1 0 Virus envelope protein E26 RabGAP-TBC PF00566.18 KFM76008.1 - 1.7e-07 31.1 0.2 2e-07 30.9 0.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Coa1 PF08695.10 KFM76009.1 - 1.1e-10 41.2 0.0 1.4e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 HTH_Tnp_Tc3_2 PF01498.18 KFM76010.1 - 6.4e-14 52.0 0.5 1.2e-13 51.0 0.5 1.5 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 KFM76010.1 - 0.00022 20.9 0.1 0.00087 19.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM76010.1 - 0.00044 20.2 0.8 0.0043 17.0 0.0 2.4 2 1 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 KFM76010.1 - 0.00053 19.3 3.5 0.0093 15.4 0.3 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KFM76010.1 - 0.00074 19.6 2.1 0.00091 19.3 0.1 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76010.1 - 0.00079 19.2 1.8 0.011 15.5 0.1 2.8 3 1 0 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.15 KFM76010.1 - 0.0012 18.9 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_IclR PF09339.10 KFM76010.1 - 0.038 13.8 1.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_31 PF13560.6 KFM76010.1 - 0.058 13.7 6.6 0.066 13.6 0.2 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM76010.1 - 0.1 12.6 0.1 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 KFM76010.1 - 0.19 11.5 0.8 7 6.6 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain LRR_8 PF13855.6 KFM76013.1 - 4.3e-36 122.5 50.9 3.2e-12 46.0 6.3 5.2 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFM76013.1 - 4.1e-27 93.8 26.0 1.9e-06 28.1 4.1 6.2 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM76013.1 - 6.1e-09 35.6 9.9 9.7e-06 25.2 3.9 2.5 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFM76013.1 - 2.1e-06 27.5 21.2 6.9 7.6 0.0 9.8 8 2 0 8 8 8 2 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 KFM76013.1 - 0.12 12.4 0.1 6.5 6.9 0.0 3.3 3 1 1 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 KFM76013.1 - 0.58 10.4 36.6 3.8 7.8 0.0 9.8 11 0 0 11 11 11 0 Leucine Rich repeat TRM13 PF05206.14 KFM76015.1 - 7.4e-63 212.5 6.9 8.4e-63 212.3 6.9 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_28 PF02636.17 KFM76015.1 - 0.064 12.9 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase zf-U11-48K PF05253.12 KFM76016.1 - 2.2e-10 40.2 2.9 4.1e-10 39.3 2.9 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 KFM76016.1 - 1.2e-09 37.8 4.0 1.2e-09 37.8 4.0 2.1 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Vps39_1 PF10366.9 KFM76017.1 - 2e-33 114.9 2.6 2e-33 114.9 2.6 3.3 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 KFM76017.1 - 6.5e-28 98.1 0.2 2.6e-27 96.1 0.0 2.1 3 0 0 3 3 3 1 CNH domain Vps39_2 PF10367.9 KFM76017.1 - 8.3e-25 87.4 2.2 3.2e-24 85.5 2.2 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 KFM76017.1 - 5.7e-14 52.2 7.3 2e-07 31.0 0.5 3.1 2 0 0 2 2 2 2 Region in Clathrin and VPS DUF4566 PF15130.6 KFM76017.1 - 0.0047 16.4 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) TPR_12 PF13424.6 KFM76017.1 - 0.03 14.6 5.4 1.2 9.4 0.1 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM76017.1 - 0.19 11.7 0.1 2.2 8.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 KFM76017.1 - 0.36 11.2 6.0 5.8 7.4 0.1 4.8 6 0 0 6 6 6 0 PPR repeat TPR_1 PF00515.28 KFM76017.1 - 5.5 7.0 8.7 62 3.7 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Spaetzle PF16077.5 KFM76018.1 - 4.6e-14 52.7 3.7 1.4e-13 51.2 3.7 1.8 1 1 0 1 1 1 1 Spaetzle Coagulin PF02035.15 KFM76018.1 - 1.6e-05 24.9 0.6 2.4e-05 24.3 0.6 1.2 1 0 0 1 1 1 1 Coagulin CUB PF00431.20 KFM76020.1 - 1.2e-74 247.7 0.0 6.1e-28 97.4 0.0 3.3 3 0 0 3 3 3 3 CUB domain EGF PF00008.27 KFM76020.1 - 8.8e-30 102.7 109.6 5.1e-09 36.3 9.8 9.5 8 1 0 8 8 8 7 EGF-like domain EGF_CA PF07645.15 KFM76020.1 - 2.1e-24 85.4 110.4 3.8e-07 30.2 3.8 8.8 5 2 3 8 8 8 6 Calcium-binding EGF domain EGF_3 PF12947.7 KFM76020.1 - 4.3e-15 55.6 105.7 1.2e-05 25.4 3.7 9.1 8 0 0 8 8 8 5 EGF domain hEGF PF12661.7 KFM76020.1 - 5.1e-14 52.3 97.8 3.6e-05 24.2 6.4 10.6 10 2 0 10 10 10 5 Human growth factor-like EGF FXa_inhibition PF14670.6 KFM76020.1 - 2.3e-09 37.3 115.2 0.0089 16.3 9.6 9.0 7 1 1 8 8 8 6 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 KFM76020.1 - 8e-08 32.5 119.9 0.00014 22.1 10.3 9.6 7 2 1 8 8 8 5 EGF-like domain CUB_2 PF02408.20 KFM76020.1 - 1.6e-06 27.8 0.3 0.00053 19.7 0.1 3.6 3 1 0 3 3 3 1 CUB-like domain cEGF PF12662.7 KFM76020.1 - 7.2e-05 22.6 11.6 0.00016 21.5 3.3 10.2 8 1 0 8 8 8 4 Complement Clr-like EGF-like CUB PF00431.20 KFM76021.1 - 0 1311.8 9.4 6.3e-30 103.7 0.0 18.0 18 0 0 18 18 18 18 CUB domain CUB_2 PF02408.20 KFM76021.1 - 1e-15 57.5 12.5 0.49 10.2 0.1 11.9 10 1 1 11 11 11 8 CUB-like domain Sec6 PF06046.13 KFM76024.1 - 0.022 13.2 0.0 0.022 13.1 0.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec6 CBM_14 PF01607.24 KFM76025.1 - 5.3e-31 106.5 28.8 5.2e-12 45.7 5.5 3.1 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain RVT_1 PF00078.27 KFM76026.1 - 5.4e-34 117.6 0.1 8.4e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTB_2 PF02214.22 KFM76027.1 - 2.4e-17 63.1 0.0 4.4e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFM76027.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain BTB_3 PF16017.5 KFM76027.1 - 0.034 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain TIM21 PF08294.11 KFM76028.1 - 1.5e-47 161.1 0.3 3.1e-47 160.1 0.1 1.5 2 0 0 2 2 2 1 TIM21 Coa1 PF08695.10 KFM76028.1 - 3.5e-07 30.0 0.0 7.6e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 UQ_con PF00179.26 KFM76029.1 - 3.4e-45 153.2 0.0 4.1e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM76029.1 - 7.2e-05 23.0 0.1 0.00015 22.0 0.1 1.7 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KFM76029.1 - 0.0081 16.0 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 UEV domain UFC1 PF08694.11 KFM76029.1 - 0.015 14.9 0.0 0.032 13.9 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 KFM76029.1 - 0.04 13.6 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Thymosin PF01290.20 KFM76030.1 - 9.4e-71 233.3 43.9 3.5e-17 61.9 8.0 5.1 5 0 0 5 5 5 5 Thymosin beta-4 family DUF4522 PF15022.6 KFM76030.1 - 3.2e-06 27.4 13.0 0.99 9.7 0.1 5.0 1 1 4 5 5 5 3 Protein of unknown function (DUF4522) RNA_pol_Rpb1_2 PF00623.20 KFM76030.1 - 0.45 10.7 2.9 4.3 7.5 0.1 2.3 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 2 TMEM237 PF15383.6 KFM76030.1 - 1.2 8.1 3.1 25 3.8 0.0 2.3 2 1 0 2 2 2 0 Transmembrane protein 237 WH2 PF02205.20 KFM76030.1 - 1.6 8.7 19.4 14 5.7 0.0 4.9 5 0 0 5 5 5 0 WH2 motif GDC-P PF02347.16 KFM76031.1 - 8.5e-190 631.1 0.5 2.5e-182 606.5 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KFM76031.1 - 1.7e-06 27.5 0.0 8.3e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFM76031.1 - 0.00019 20.5 0.0 0.00053 19.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V HTH_Tnp_Tc3_2 PF01498.18 KFM76032.1 - 2.8e-16 59.5 3.0 4.4e-16 58.9 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76032.1 - 9.4e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Exo_endo_phos PF03372.23 KFM76033.1 - 1.9e-06 27.6 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family p450 PF00067.22 KFM76034.1 - 3.3e-100 336.0 0.2 7.4e-99 331.6 0.2 2.0 1 1 0 1 1 1 1 Cytochrome P450 YlaC PF10777.9 KFM76034.1 - 0.094 12.6 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Inner membrane protein YlaC p450 PF00067.22 KFM76035.1 - 4.8e-102 342.1 1.5 4.2e-101 339.0 1.5 1.9 1 1 0 1 1 1 1 Cytochrome P450 Spaetzle PF16077.5 KFM76036.1 - 8.9e-09 35.8 3.9 9.1e-09 35.7 3.9 1.0 1 0 0 1 1 1 1 Spaetzle DUF2807 PF10988.8 KFM76038.1 - 0.012 15.5 1.7 0.012 15.5 1.7 7.1 1 1 5 6 6 6 0 Putative auto-transporter adhesin, head GIN domain HTH_Tnp_Tc3_2 PF01498.18 KFM76040.1 - 2.5e-16 59.6 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76040.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4371 PF14291.6 KFM76041.1 - 6.1e-05 22.8 0.0 6.8e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF3557 PF12078.8 KFM76041.1 - 0.011 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) Skp1_POZ PF03931.15 KFM76041.1 - 0.08 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DDE_Tnp_4 PF13359.6 KFM76042.1 - 2.1e-12 47.0 0.0 2.7e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KFM76042.1 - 0.00083 19.1 0.0 0.00094 18.9 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 KFM76043.1 - 5e-16 58.7 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76043.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76043.1 - 2e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76043.1 - 0.0026 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76043.1 - 2.4 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Met_10 PF02475.16 KFM76044.1 - 2e-34 119.1 0.0 2.7e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KFM76044.1 - 9e-05 22.1 0.0 0.00022 20.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain DNA_methylase PF00145.17 KFM76044.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.15 KFM76044.1 - 0.039 13.6 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.11 KFM76044.1 - 0.046 12.7 0.1 0.34 9.9 0.0 1.9 1 1 1 2 2 2 0 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 KFM76044.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KFM76044.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CH PF00307.31 KFM76046.1 - 3.1e-20 72.4 0.1 4.1e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KFM76046.1 - 1.1e-15 56.9 2.4 5.5e-13 48.3 3.3 2.7 3 0 0 3 3 3 2 Calponin family repeat CDC24 PF06395.11 KFM76046.1 - 0.0051 17.0 0.1 0.0083 16.4 0.1 1.3 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.8 KFM76046.1 - 0.007 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain Rsc14 PF08586.10 KFM76048.1 - 0.023 15.5 1.2 0.038 14.8 1.0 1.5 1 1 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit DUF3656 PF12392.8 KFM76048.1 - 0.23 12.1 3.4 0.33 11.6 3.4 1.5 1 1 0 1 1 1 0 Collagenase Asp-B-Hydro_N PF05279.11 KFM76048.1 - 5.4 7.0 14.3 8 6.5 14.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.25 KFM76049.1 - 1.7e-46 158.8 0.0 1.9e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM76049.1 - 9.9e-32 110.2 0.0 1.1e-31 110.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM76049.1 - 4.1e-09 36.2 0.0 5.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM76049.1 - 2.8e-05 23.6 0.1 4.1e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFM76049.1 - 0.0002 20.3 0.0 0.00023 20.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KFM76049.1 - 0.03 13.9 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFM76049.1 - 0.052 13.1 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 RIO1 family TTRAP PF14203.6 KFM76049.1 - 0.062 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Haspin_kinase PF12330.8 KFM76049.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RCC1 PF00415.18 KFM76050.1 - 1.8e-06 28.5 1.4 5.7e-05 23.7 0.6 2.0 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM76050.1 - 0.0017 18.1 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat DDE_3 PF13358.6 KFM76051.1 - 5.1e-16 58.7 0.1 5.6e-15 55.4 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76051.1 - 8e-16 58.1 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76051.1 - 0.00078 20.0 1.5 0.00078 20.0 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76051.1 - 0.0029 17.3 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76051.1 - 0.016 15.3 0.1 0.069 13.3 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM76051.1 - 0.037 14.1 2.6 0.038 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Myb_DNA-bind_5 PF13873.6 KFM76052.1 - 0.00018 21.5 0.0 0.0002 21.3 0.0 1.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-H2C2_2 PF13465.6 KFM76053.1 - 2.6e-39 131.9 56.2 1.1e-08 35.1 3.0 7.5 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76053.1 - 3.3e-26 90.2 62.3 2.5e-06 27.6 1.8 7.2 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76053.1 - 1.1e-23 81.8 56.2 8e-05 23.2 1.1 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM76053.1 - 1.3e-09 38.1 50.2 0.004 17.5 1.1 6.8 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM76053.1 - 8.3e-07 28.7 44.8 0.015 15.1 1.2 7.5 7 1 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM76053.1 - 4.1e-05 23.4 44.5 0.15 12.1 2.0 6.8 6 1 0 6 6 6 5 C2H2-type zinc finger BolA PF01722.18 KFM76053.1 - 9e-05 22.7 3.8 17 5.8 0.0 4.8 1 1 4 5 5 5 1 BolA-like protein zf-C2H2_11 PF16622.5 KFM76053.1 - 0.064 13.0 0.2 0.064 13.0 0.2 6.6 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM76053.1 - 0.12 12.7 0.3 0.12 12.7 0.3 6.0 5 1 1 6 6 6 0 Zinc-finger double-stranded RNA-binding Rhodanese PF00581.20 KFM76054.1 - 6.8e-10 39.4 0.0 1.2e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 KFM76054.1 - 9.2e-05 22.3 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF3894 PF13033.6 KFM76055.1 - 0.0072 16.4 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3894) ANAPC2 PF08672.11 KFM76055.1 - 0.028 14.9 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 Pre-SET PF05033.16 KFM76056.1 - 2.8e-16 60.1 6.7 4.6e-16 59.4 6.7 1.4 1 0 0 1 1 1 1 Pre-SET motif Phosducin PF02114.16 KFM76056.1 - 0.041 12.8 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosducin Chromo PF00385.24 KFM76057.1 - 4.6e-12 45.7 0.3 5.1e-12 45.5 0.3 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HTH_Tnp_Tc3_2 PF01498.18 KFM76058.1 - 5e-16 58.7 4.5 5.7e-16 58.5 2.2 2.3 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM76058.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76058.1 - 2.1e-07 30.6 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76058.1 - 0.0027 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76058.1 - 2.2 8.9 15.6 0.12 13.0 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM76059.1 - 2.4e-16 59.7 2.2 6.4e-16 58.4 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76059.1 - 3e-12 46.5 0.0 5.6e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76059.1 - 2e-06 27.5 1.8 5.9e-06 25.9 0.1 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76059.1 - 0.011 15.5 0.5 0.034 14.0 0.5 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KFM76059.1 - 2.3 8.9 13.9 0.18 12.4 1.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain GAS PF13851.6 KFM76060.1 - 0.011 15.1 0.3 0.019 14.3 0.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding LppC PF04348.13 KFM76060.1 - 0.17 10.6 0.0 0.33 9.7 0.0 1.4 2 0 0 2 2 2 0 LppC putative lipoprotein Lectin_C PF00059.21 KFM76061.1 - 1.4e-34 119.0 0.7 5.6e-15 56.0 0.0 3.6 3 1 0 3 3 3 3 Lectin C-type domain UL45 PF05473.12 KFM76061.1 - 7.2e-13 48.6 1.7 3.9e-05 23.4 0.1 3.5 3 1 1 4 4 4 3 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KFM76061.1 - 0.00067 20.0 1.4 3.7 8.0 0.1 3.5 3 0 0 3 3 3 2 Extracellular link domain Chordopox_A33R PF05966.12 KFM76061.1 - 0.0033 16.7 4.6 0.29 10.4 0.1 3.0 3 1 0 3 3 3 2 Chordopoxvirus A33R protein Intimin_C PF07979.11 KFM76061.1 - 0.012 16.0 0.4 6.7 7.2 0.0 3.2 3 1 0 3 3 3 0 Intimin C-type lectin domain PDGF PF00341.17 KFM76063.1 - 1.9e-12 47.3 2.9 1.9e-12 47.3 2.9 2.3 2 1 0 2 2 2 1 PDGF/VEGF domain HTH_Tnp_Tc3_2 PF01498.18 KFM76064.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76064.1 - 5.9e-13 48.8 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76064.1 - 1.9e-07 30.7 1.2 6.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76064.1 - 0.0025 17.5 0.6 0.0072 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76064.1 - 2.1 9.0 15.6 0.12 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain WD40 PF00400.32 KFM76065.1 - 7.3e-15 55.1 16.7 2.7e-07 31.2 0.1 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM76065.1 - 0.00064 20.0 0.1 1.1 9.6 0.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Kinesin PF00225.23 KFM76066.1 - 7.2e-46 156.6 0.0 8.3e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM76066.1 - 6.9e-30 104.0 0.1 9.2e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 KFM76066.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KFM76066.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 KFM76066.1 - 0.22 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 KFM76067.1 - 1.4e-59 201.7 2.7 1.4e-59 201.7 2.7 3.4 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bind PF13931.6 KFM76067.1 - 1.3e-17 64.4 1.0 1.3e-17 64.4 1.0 5.7 3 2 1 4 4 4 2 Kinesin-associated microtubule-binding Fib_alpha PF08702.10 KFM76067.1 - 1.2 9.4 66.4 0.15 12.2 11.0 7.4 3 2 4 7 7 7 0 Fibrinogen alpha/beta chain family DUF501 PF04417.12 KFM76067.1 - 8.8 6.1 10.6 0.14 11.9 0.7 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF501) hSac2 PF12456.8 KFM76068.1 - 0.028 14.1 0.2 0.065 13.0 0.2 1.6 1 0 0 1 1 1 0 Inositol phosphatase DUF4476 PF14771.6 KFM76069.1 - 0.015 15.6 1.3 0.14 12.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4476) GOLGA2L5 PF15070.6 KFM76069.1 - 0.055 12.1 0.1 0.066 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 FAD-oxidase_C PF02913.19 KFM76070.1 - 4.4e-45 154.3 0.0 5.8e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFM76070.1 - 1.7e-39 134.8 0.0 3.2e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain CUB PF00431.20 KFM76071.1 - 5.1e-41 139.4 0.5 1.9e-19 70.0 1.0 2.2 2 0 0 2 2 2 2 CUB domain QSregVF PF13652.6 KFM76071.1 - 0.2 11.7 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor CBM_21 PF03370.13 KFM76072.1 - 1.5e-29 102.4 3.5 3.4e-29 101.3 3.5 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFM76072.1 - 9.4e-12 45.4 2.2 9.4e-12 45.4 2.2 2.2 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) Morc6_S5 PF17942.1 KFM76075.1 - 0.072 13.1 0.0 0.072 13.1 0.0 1.0 1 0 0 1 1 1 0 Morc6 ribosomal protein S5 domain 2-like DDE_3 PF13358.6 KFM76076.1 - 6.9e-16 58.3 0.3 6.5e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76076.1 - 8.4e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76076.1 - 0.00078 20.0 1.5 0.00078 20.0 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76076.1 - 0.0015 18.3 0.0 0.064 13.1 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76076.1 - 0.013 15.6 0.1 0.051 13.7 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM76076.1 - 0.019 15.0 2.1 0.034 14.2 0.2 2.4 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.8 KFM76076.1 - 0.029 14.2 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase HTH_7 PF02796.15 KFM76076.1 - 0.11 12.5 0.0 0.37 10.9 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 KFM76077.1 - 0.00014 21.6 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Bac_DnaA_C PF08299.11 KFM76077.1 - 0.0051 16.8 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix HTH_Tnp_Tc3_2 PF01498.18 KFM76078.1 - 2.3e-16 59.8 2.2 7e-16 58.2 2.2 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76078.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76078.1 - 3.7e-07 29.8 1.6 8.4e-07 28.7 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76078.1 - 0.0034 17.1 0.5 0.009 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76078.1 - 4.9 7.8 13.9 0.36 11.5 1.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain TUDOR PF00567.24 KFM76079.1 - 6.1e-39 132.8 0.5 3.9e-21 75.3 0.1 2.3 2 0 0 2 2 2 2 Tudor domain DUF1357 PF07094.11 KFM76079.1 - 0.028 14.5 0.1 0.046 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) DUF5030 PF16433.5 KFM76079.1 - 0.049 13.0 0.1 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5030) DUF1281_C PF18406.1 KFM76079.1 - 0.15 11.8 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein FlxA PF14282.6 KFM76080.1 - 0.0071 16.3 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 FlxA-like protein MRFAP1 PF15155.6 KFM76080.1 - 0.032 14.7 0.9 1.2 9.7 0.2 2.2 1 1 1 2 2 2 0 MORF4 family-associated protein1 Glycos_transf_2 PF00535.26 KFM76080.1 - 0.11 12.3 0.2 1.3 8.8 0.0 2.0 1 1 1 2 2 2 0 Glycosyl transferase family 2 Conotoxin PF02950.17 KFM76080.1 - 0.13 13.3 1.3 0.21 12.7 1.3 1.3 1 0 0 1 1 1 0 Conotoxin DDE_1 PF03184.19 KFM76081.1 - 8.1e-05 22.3 0.0 0.0001 22.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM76082.1 - 7.9e-54 177.8 67.2 1.2e-08 35.0 1.1 9.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76082.1 - 1.1e-33 113.8 77.4 8.8e-06 25.9 2.0 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76082.1 - 9.2e-24 82.1 69.8 0.00098 19.8 1.7 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM76082.1 - 5.8e-21 74.2 52.1 0.00014 22.1 0.1 8.7 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM76082.1 - 3.1e-17 62.1 50.3 0.0026 17.7 0.8 8.6 8 1 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM76082.1 - 1.2e-13 51.0 38.6 0.23 11.8 0.0 8.4 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM76082.1 - 5.7e-07 29.5 27.4 0.37 10.9 0.8 7.8 3 2 5 8 8 8 3 Sec23/Sec24 zinc finger BolA PF01722.18 KFM76082.1 - 2.3e-05 24.6 8.7 0.15 12.4 0.5 4.5 1 1 3 4 4 4 2 BolA-like protein ADK_lid PF05191.14 KFM76082.1 - 6.5e-05 22.8 25.5 0.17 11.9 1.8 6.0 2 1 5 7 7 7 3 Adenylate kinase, active site lid C1_1 PF00130.22 KFM76082.1 - 0.00088 19.1 40.4 2 8.4 5.3 7.6 2 2 6 8 8 8 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 KFM76082.1 - 0.0014 18.7 27.8 6.9 6.9 0.1 8.1 8 0 0 8 8 8 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 KFM76082.1 - 0.0085 15.9 27.6 1.1 9.2 0.2 7.4 3 3 5 8 8 8 1 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM76082.1 - 0.015 15.4 22.7 0.61 10.2 5.9 4.2 1 1 2 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type ribosomal_L24 PF17136.4 KFM76082.1 - 0.04 14.3 1.0 2.6 8.5 0.0 3.4 3 0 0 3 3 3 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 YyzF PF14116.6 KFM76082.1 - 0.051 13.6 23.1 15 5.7 0.1 7.7 8 0 0 8 8 8 0 YyzF-like protein zf-HIT PF04438.16 KFM76082.1 - 0.13 12.2 36.0 1.4 8.8 1.4 8.0 8 0 0 8 8 8 0 HIT zinc finger zinc_ribbon_15 PF17032.5 KFM76082.1 - 0.4 11.5 23.0 7.8 7.3 0.8 4.5 1 1 5 6 6 6 0 zinc-ribbon family GAGA PF09237.11 KFM76082.1 - 0.44 10.4 16.9 7.3 6.5 0.0 6.1 2 2 5 7 7 7 0 GAGA factor XPA_N PF01286.18 KFM76082.1 - 0.45 10.6 30.5 2.2 8.4 0.1 7.8 8 0 0 8 8 8 0 XPA protein N-terminal zf_UBZ PF18439.1 KFM76082.1 - 1.2 8.8 27.7 11 5.8 0.2 7.9 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM76082.1 - 3 8.2 48.6 2.1 8.7 0.2 7.6 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 KFM76082.1 - 3.5 7.8 35.3 0.34 11.0 0.6 7.4 1 1 5 7 7 7 0 KIAA1045 RING finger DUF3268 PF11672.8 KFM76082.1 - 3.7 7.9 14.8 2.1 8.7 0.3 3.9 2 1 0 3 3 3 0 zinc-finger-containing domain zf-MYST PF17772.1 KFM76082.1 - 4.3 7.0 33.5 0.83 9.3 0.5 7.0 7 1 1 8 8 8 0 MYST family zinc finger domain Zn-ribbon_8 PF09723.10 KFM76082.1 - 6.6 6.9 26.4 3.3 7.9 1.0 5.7 1 1 7 8 8 8 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 KFM76083.1 - 4.3e-15 55.3 9.3 8.4e-06 26.0 0.1 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76083.1 - 1.6e-12 47.1 14.0 1.6e-06 28.2 2.4 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76083.1 - 1.4e-09 37.9 12.6 4.7e-05 23.9 0.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFM76083.1 - 7.8e-07 29.3 7.1 0.0011 19.2 2.1 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM76083.1 - 1.5e-05 25.1 4.4 0.045 14.0 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM76083.1 - 2.6e-05 24.1 7.6 0.017 15.1 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM76083.1 - 2.8e-05 23.8 6.3 0.007 16.1 0.2 3.3 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM76083.1 - 3.5e-05 23.6 0.6 0.23 11.4 0.1 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM76083.1 - 0.00036 20.1 0.8 0.3 10.7 0.1 2.1 2 0 0 2 2 2 2 MYST family zinc finger domain zf_UBZ PF18439.1 KFM76083.1 - 0.0012 18.4 2.4 0.17 11.5 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFM76083.1 - 0.0015 18.8 4.4 0.0015 18.8 4.4 1.6 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFM76083.1 - 0.0022 18.2 1.3 0.077 13.3 0.1 2.0 1 1 1 2 2 2 1 BolA-like protein zf-BED PF02892.15 KFM76083.1 - 0.0026 17.7 7.4 0.25 11.4 0.9 2.1 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_9 PF16293.5 KFM76083.1 - 0.0035 17.1 3.7 0.39 10.6 0.2 2.4 1 1 1 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM76083.1 - 0.0072 16.4 0.6 1.7 8.8 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM76083.1 - 0.0091 15.8 0.2 0.18 11.6 0.0 2.1 1 1 1 2 2 2 1 GAGA factor zf-DBF PF07535.12 KFM76083.1 - 0.01 15.9 1.5 0.3 11.2 0.2 2.3 2 0 0 2 2 2 0 DBF zinc finger HNH_5 PF14279.6 KFM76083.1 - 0.011 15.5 1.1 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease C1_1 PF00130.22 KFM76083.1 - 0.013 15.4 3.4 0.45 10.4 0.6 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KFM76083.1 - 0.022 14.9 2.3 1.2 9.3 0.1 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KFM76083.1 - 0.023 15.0 7.0 0.25 11.7 0.6 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) VATC PF18716.1 KFM76083.1 - 0.033 14.0 0.7 3 7.8 0.1 2.2 2 0 0 2 2 2 0 Vms1-associating treble clef domain DZR PF12773.7 KFM76083.1 - 0.04 13.9 0.2 0.051 13.6 0.2 1.1 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 KFM76083.1 - 0.049 13.6 1.7 4.5 7.3 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf_C2H2_ZHX PF18387.1 KFM76083.1 - 0.058 13.0 2.7 2.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Baculo_IE-1 PF05290.11 KFM76083.1 - 0.06 13.3 3.3 4.8 7.1 3.3 2.0 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) HTH_5 PF01022.20 KFM76083.1 - 0.085 12.7 1.8 0.98 9.3 0.6 2.2 1 1 1 2 2 2 0 Bacterial regulatory protein, arsR family Ta0938 PF11494.8 KFM76083.1 - 0.13 12.6 0.9 5.1 7.4 0.2 2.1 1 1 1 2 2 2 0 Ta0938 gag_pre-integrs PF13976.6 KFM76083.1 - 0.14 12.0 4.9 2.6 8.0 0.5 2.2 1 1 1 2 2 2 0 GAG-pre-integrase domain LIM PF00412.22 KFM76083.1 - 0.15 12.3 4.3 2.7 8.3 1.2 2.1 1 1 1 2 2 2 0 LIM domain DUF2225 PF09986.9 KFM76083.1 - 1.3 8.7 5.8 5.9 6.6 0.9 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn-C2H2_12 PF18112.1 KFM76083.1 - 3.3 8.2 9.5 7.6 7.1 1.6 3.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Sulfatase PF00884.23 KFM76084.1 - 1.6e-45 155.8 0.0 1.1e-43 149.9 0.0 2.1 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.22 KFM76084.1 - 1.8e-06 27.8 0.0 0.024 14.2 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFM76084.1 - 0.0017 18.6 0.0 0.0043 17.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KFM76084.1 - 0.028 13.0 0.0 0.094 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Ion_trans PF00520.31 KFM76085.1 - 5e-21 75.1 7.2 6.4e-21 74.7 7.2 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFM76085.1 - 1.3e-20 73.3 0.0 2.1e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CLZ PF16526.5 KFM76085.1 - 2.3e-06 27.8 1.7 7.3e-06 26.3 1.3 2.1 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ion_trans_2 PF07885.16 KFM76085.1 - 0.0016 18.4 10.3 0.0081 16.1 10.3 2.3 1 1 0 1 1 1 1 Ion channel DUF3472 PF11958.8 KFM76086.1 - 0.1 13.1 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) Sulfotransfer_1 PF00685.27 KFM76087.1 - 8.4e-20 71.4 0.0 1.2e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM76087.1 - 2.4e-12 47.7 0.0 3.2e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family TGFb_propeptide PF00688.18 KFM76088.1 - 6.7e-53 179.9 0.2 9.2e-53 179.5 0.2 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFM76088.1 - 2.9e-22 79.6 0.4 1e-21 77.8 0.2 2.0 2 0 0 2 2 2 1 Transforming growth factor beta like domain AIG2_2 PF13772.6 KFM76090.1 - 7.5e-13 48.7 0.5 1.6e-12 47.6 0.1 1.8 3 0 0 3 3 3 1 AIG2-like family GGACT PF06094.12 KFM76090.1 - 3.2e-08 34.2 0.0 3.6e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ChaC PF04752.12 KFM76090.1 - 0.08 13.0 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 ChaC-like protein DUF667 PF05018.13 KFM76091.1 - 6.4e-94 312.9 0.4 7.1e-94 312.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) SPT_ssu-like PF11779.8 KFM76092.1 - 0.094 12.4 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Peptidase_M13_N PF05649.13 KFM76093.1 - 1e-14 55.1 0.0 1.2e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM76094.1 - 9.6e-28 97.2 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 HTH_Tnp_Tc3_2 PF01498.18 KFM76095.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76095.1 - 1.2e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76095.1 - 4.4e-06 26.4 1.8 1.1e-05 25.1 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76095.1 - 0.0026 17.5 0.9 0.0076 16.0 0.9 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Jnk-SapK_ap_N PF09744.9 KFM76097.1 - 5.8e-29 101.3 31.0 6.3e-29 101.2 14.2 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 DUF4472 PF14739.6 KFM76097.1 - 0.17 12.6 25.1 1.2 9.9 13.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) FAM76 PF16046.5 KFM76097.1 - 0.27 10.6 25.4 0.96 8.7 25.1 1.8 1 1 1 2 2 2 0 FAM76 protein DcrB PF08786.11 KFM76097.1 - 0.76 9.9 8.2 0.56 10.3 0.3 2.3 1 1 1 2 2 2 0 DcrB ERM PF00769.19 KFM76097.1 - 2.6 7.8 25.9 1.6 8.5 14.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HTH_Tnp_Tc3_2 PF01498.18 KFM76098.1 - 5.2e-16 58.6 3.5 6e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76098.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76098.1 - 2.1e-07 30.6 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76098.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76098.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 KFM76099.1 - 1.3e-27 94.9 41.8 2.7e-07 30.7 0.9 6.9 7 0 0 7 7 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76099.1 - 3.2e-27 93.4 51.7 9.5e-07 28.9 1.4 6.6 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76099.1 - 7.9e-16 57.4 48.7 0.00036 21.1 0.6 7.1 7 0 0 7 7 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM76099.1 - 2.3e-12 46.8 14.8 0.013 15.8 0.1 5.4 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding HTH_Tnp_Tc3_2 PF01498.18 KFM76099.1 - 6.9e-11 42.2 0.4 1.6e-10 41.0 0.4 1.6 1 0 0 1 1 1 1 Transposase zf-met PF12874.7 KFM76099.1 - 3.3e-10 40.0 27.4 0.064 13.7 0.1 5.8 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM76099.1 - 1.7e-07 30.8 27.5 0.079 12.7 0.1 5.8 5 0 0 5 5 5 5 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM76099.1 - 3.2e-07 30.2 31.3 0.058 13.4 1.6 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM76099.1 - 0.00012 21.8 27.5 0.0015 18.2 0.8 5.4 5 0 0 5 5 5 2 zinc-finger C2H2-type GAGA PF09237.11 KFM76099.1 - 0.017 14.9 7.8 0.96 9.3 0.1 3.8 1 1 3 4 4 4 0 GAGA factor zf-BED PF02892.15 KFM76099.1 - 0.031 14.3 1.4 0.031 14.3 1.4 5.5 3 2 1 4 4 4 0 BED zinc finger zf-C2H2_2 PF12756.7 KFM76099.1 - 0.032 14.6 29.5 1 9.8 0.6 6.1 2 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) HTH_32 PF13565.6 KFM76099.1 - 0.081 13.6 0.3 0.16 12.6 0.3 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_31 PF13560.6 KFM76099.1 - 0.11 12.9 0.4 0.3 11.5 0.3 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 KFM76099.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 MarR family zf-C2HE PF16278.5 KFM76099.1 - 0.2 12.1 12.8 11 6.5 1.3 4.3 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DNA_primase_S PF01896.19 KFM76099.1 - 0.27 11.3 4.0 15 5.6 0.7 3.0 2 1 0 2 2 2 0 DNA primase small subunit BolA PF01722.18 KFM76099.1 - 0.78 10.1 2.5 20 5.5 1.1 2.9 1 1 2 3 3 3 0 BolA-like protein Zn-ribbon_8 PF09723.10 KFM76099.1 - 0.8 9.9 12.1 37 4.6 0.8 5.0 5 1 0 5 5 5 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM76099.1 - 0.87 10.4 11.8 4.3 8.2 1.5 3.3 1 1 3 4 4 4 0 zinc-ribbon family Zn_ribbon_recom PF13408.6 KFM76099.1 - 1 9.9 14.0 3.2 8.3 2.9 2.7 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2H2_3rep PF18868.1 KFM76099.1 - 1.8 9.2 12.2 47 4.7 8.8 3.9 2 1 1 3 3 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KFM76099.1 - 3.4 7.3 6.7 20 4.8 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KFM76099.1 - 3.9 7.4 11.8 61 3.6 0.1 5.6 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) C1_4 PF07975.12 KFM76099.1 - 4.6 7.6 14.1 8.4 6.7 3.2 3.3 1 1 3 4 4 4 0 TFIIH C1-like domain Tnp_P_element PF12017.8 KFM76100.1 - 0.001 18.5 0.2 0.0012 18.3 0.2 1.1 1 0 0 1 1 1 1 Transposase protein zf-C2H2 PF00096.26 KFM76102.1 - 3.6e-10 39.7 9.1 6.8e-06 26.2 0.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM76102.1 - 1.8e-07 31.2 11.7 2.1e-06 27.9 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM76102.1 - 2e-06 28.1 6.0 8e-05 23.2 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM76102.1 - 0.00025 20.7 2.0 0.00025 20.7 2.0 2.8 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM76102.1 - 0.0015 18.3 0.9 0.0015 18.3 0.9 2.5 2 1 0 2 2 2 1 zinc-finger of a C2HC-type DUF4918 PF16265.5 KFM76102.1 - 0.0045 16.5 0.3 0.0093 15.5 0.2 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4918) zf-met PF12874.7 KFM76102.1 - 0.016 15.6 0.1 0.016 15.6 0.1 2.7 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM76102.1 - 0.036 14.1 3.6 0.11 12.6 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 KFM76102.1 - 0.037 14.5 4.0 2.1 8.9 0.4 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger C1_2 PF03107.16 KFM76102.1 - 0.057 13.8 3.1 5.4 7.4 0.2 2.4 2 0 0 2 2 2 0 C1 domain zf-C2H2_11 PF16622.5 KFM76102.1 - 0.13 12.0 0.2 0.13 12.0 0.2 2.9 2 1 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFM76102.1 - 0.14 12.8 1.8 9.7 6.9 0.1 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_7 PF15269.6 KFM76102.1 - 0.57 10.3 8.1 0.43 10.7 0.5 2.5 1 1 1 2 2 2 0 Zinc-finger zf-C2H2 PF00096.26 KFM76104.1 - 9.4e-06 25.8 0.8 9.4e-06 25.8 0.8 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76104.1 - 0.00043 20.9 0.8 0.00043 20.9 0.8 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM76104.1 - 0.0011 19.2 1.0 0.024 14.9 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF2688 PF10892.8 KFM76104.1 - 0.0038 16.7 0.1 0.0063 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2688) zf-met PF12874.7 KFM76104.1 - 0.0058 17.0 1.5 0.017 15.5 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Actin_micro PF17003.5 KFM76104.1 - 0.0088 15.3 1.1 0.0094 15.2 1.1 1.0 1 0 0 1 1 1 1 Putative actin-like family zf-BED PF02892.15 KFM76104.1 - 0.016 15.2 1.5 0.024 14.6 1.5 1.3 1 0 0 1 1 1 0 BED zinc finger Peptidase_M16 PF00675.20 KFM76105.1 - 1.8e-44 151.3 0.1 6.9e-44 149.4 0.1 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFM76105.1 - 2.4e-28 99.4 0.0 3.3e-26 92.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF725 PF05267.12 KFM76105.1 - 0.031 14.3 0.3 0.081 12.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF725) P16-Arc PF04699.14 KFM76105.1 - 0.092 13.2 1.1 3.7 8.0 0.0 2.6 3 0 0 3 3 3 0 ARP2/3 complex 16 kDa subunit (p16-Arc) RPAP1_N PF08621.10 KFM76105.1 - 0.75 9.6 4.9 0.5 10.2 2.3 2.0 2 0 0 2 2 2 0 RPAP1-like, N-terminal FAM86 PF14904.6 KFM76106.1 - 3.5e-09 36.6 0.0 5.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function DUF3514 PF12027.8 KFM76106.1 - 0.076 12.7 0.1 0.1 12.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3514) Chromo_shadow PF01393.19 KFM76107.1 - 1.7e-25 88.8 0.4 3.4e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 Chromo shadow domain THAP PF05485.12 KFM76107.1 - 5.1e-18 65.8 1.1 5.1e-18 65.8 1.1 2.3 2 1 1 3 3 3 1 THAP domain Chromo PF00385.24 KFM76107.1 - 0.043 13.7 0.1 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Metallophos PF00149.28 KFM76108.1 - 3.5e-05 24.4 0.2 4.6e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase COesterase PF00135.28 KFM76111.1 - 2.4e-88 297.3 0.0 3e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM76111.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold EBP PF05241.12 KFM76111.1 - 0.034 13.6 0.5 0.083 12.3 0.1 1.8 2 0 0 2 2 2 0 Emopamil binding protein HTH_IclR PF09339.10 KFM76112.1 - 2.5e-06 27.2 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KFM76112.1 - 1.9e-05 24.3 0.9 3.1e-05 23.6 0.9 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76112.1 - 0.0014 19.2 2.8 0.012 16.3 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM76112.1 - 0.0072 16.2 0.1 0.0076 16.1 0.1 1.3 1 1 0 1 1 1 1 MarR family HTH_31 PF13560.6 KFM76112.1 - 0.0083 16.5 3.1 0.068 13.5 3.1 2.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KFM76112.1 - 0.0095 15.7 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KFM76112.1 - 0.0099 16.0 0.3 0.017 15.2 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.6 KFM76112.1 - 0.033 14.3 0.7 0.033 14.3 0.7 1.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_25 PF13413.6 KFM76112.1 - 0.053 13.4 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain LEAP-2 PF07359.11 KFM76112.1 - 0.058 13.2 0.5 0.095 12.5 0.5 1.5 1 1 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Sigma70_r4_2 PF08281.12 KFM76112.1 - 0.064 12.9 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.6 KFM76112.1 - 0.64 10.1 4.8 0.13 12.3 1.3 1.6 2 0 0 2 2 2 0 Winged helix-turn helix COesterase PF00135.28 KFM76113.1 - 8.3e-21 74.4 0.0 9.9e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family HTH_Tnp_Tc3_2 PF01498.18 KFM76114.1 - 2e-16 59.9 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76114.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KFM76115.1 - 0.0042 16.8 0.2 0.0072 16.0 0.1 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Cut8 PF08559.10 KFM76116.1 - 1.6e-39 136.0 3.4 2e-39 135.6 3.4 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein HTH_Tnp_Tc3_2 PF01498.18 KFM76117.1 - 4.3e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76117.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76117.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76117.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76117.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Sulfatase_C PF14707.6 KFM76118.1 - 4.1e-30 105.0 0.1 5.5e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Sulfatase PF00884.23 KFM76118.1 - 1.3e-11 44.4 0.0 2.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Sulfatase TFIIIC_delta PF12657.7 KFM76118.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Ldl_recept_a PF00057.18 KFM76119.1 - 4.1e-05 23.7 7.1 4.1e-05 23.7 7.1 2.3 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFM76119.1 - 0.004 17.5 0.1 0.0069 16.7 0.1 1.4 1 0 0 1 1 1 1 CUB domain Bestrophin PF01062.21 KFM76121.1 - 5.2e-38 131.1 0.4 5.5e-38 131.0 0.4 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Mito_carr PF00153.27 KFM76122.1 - 1.2e-21 76.4 1.1 1.4e-15 57.0 0.5 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein HTH_48 PF17906.1 KFM76123.1 - 1.3e-07 31.6 1.7 2.1e-07 30.9 0.5 1.8 2 0 0 2 2 2 1 HTH domain in Mos1 transposase DUF4817 PF16087.5 KFM76123.1 - 0.0042 16.8 0.4 0.01 15.6 0.2 1.8 1 1 1 2 2 2 1 Helix-turn-helix domain (DUF4817) Serpulina_VSP PF05540.11 KFM76123.1 - 0.043 12.8 0.0 0.051 12.6 0.0 1.0 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein ECH_1 PF00378.20 KFM76125.1 - 1.1e-52 178.9 0.0 1.4e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM76125.1 - 4.9e-31 108.4 0.0 3e-30 105.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DAGK_acc PF00609.19 KFM76126.1 - 1.9e-56 190.8 0.0 3.1e-56 190.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFM76126.1 - 5.3e-24 84.2 0.0 9.9e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RA PF00788.23 KFM76126.1 - 1.4e-21 77.0 0.0 4.1e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain TUG-UBL1 PF11470.8 KFM76126.1 - 0.00037 20.7 0.0 0.13 12.5 0.0 2.9 3 0 0 3 3 3 2 TUG ubiquitin-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM76128.1 - 3e-14 53.0 1.0 5.6e-14 52.2 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76128.1 - 7.4e-14 51.7 0.0 9.5e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76129.1 - 2.7e-16 59.5 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76129.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76129.1 - 1.8e-07 30.8 1.2 6.4e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76129.1 - 0.0024 17.6 0.6 0.0069 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76129.1 - 1.8 9.2 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain P4Ha_N PF08336.11 KFM76130.1 - 3.9e-40 137.0 1.3 7.3e-40 136.1 1.3 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFM76130.1 - 4.5e-16 59.5 0.1 8.5e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFM76130.1 - 2.6e-07 31.1 0.0 5.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1281_C PF18406.1 KFM76130.1 - 0.35 10.6 1.6 5.7 6.7 0.1 3.2 3 0 0 3 3 3 0 Ferredoxin-like domain in Api92-like protein DEAD_2 PF06733.15 KFM76131.1 - 1.4e-48 164.9 2.1 1.8e-48 164.5 2.1 1.1 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KFM76131.1 - 1.7e-06 28.1 0.6 6.3e-05 23.1 0.6 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM76131.1 - 1.8e-05 24.6 0.0 0.00095 19.0 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KFM76131.1 - 0.00014 20.7 0.2 0.0048 15.7 0.2 2.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.16 KFM76131.1 - 0.038 13.4 0.1 0.86 9.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 KFM76131.1 - 0.068 13.4 0.2 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFM76131.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 KFM76131.1 - 0.12 12.4 0.1 2.7 8.0 0.0 2.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Helicase_C_2 PF13307.6 KFM76132.1 - 2.3e-56 190.7 0.1 6.3e-56 189.2 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain Terminase_3 PF04466.13 KFM76132.1 - 0.067 12.7 2.3 0.096 12.2 1.1 1.7 1 1 1 2 2 2 0 Phage terminase large subunit HTH_Tnp_Tc3_2 PF01498.18 KFM76133.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76133.1 - 1.4e-13 50.8 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Acyl_transf_3 PF01757.22 KFM76135.1 - 1.4e-10 40.8 3.6 1.7e-10 40.5 3.6 1.1 1 0 0 1 1 1 1 Acyltransferase family Trypsin PF00089.26 KFM76137.1 - 3.7e-58 196.9 3.5 6.3e-57 192.9 0.1 2.5 2 1 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 KFM76137.1 - 0.0008 20.3 0.0 0.0031 18.4 0.0 2.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain CLIP PF12032.8 KFM76137.1 - 0.017 15.4 3.8 0.11 12.8 3.8 2.4 1 1 0 1 1 1 0 Regulatory CLIP domain of proteinases Spatacsin_C PF14649.6 KFM76141.1 - 1.4e-82 277.2 7.7 2.3e-82 276.5 7.7 1.4 1 0 0 1 1 1 1 Spatacsin C-terminus FANCI_HD1 PF14679.6 KFM76141.1 - 0.073 13.0 0.4 0.69 9.9 0.4 2.8 1 0 0 1 1 1 0 FANCI helical domain 1 eIF3_subunit PF08597.10 KFM76142.1 - 7.9e-38 130.7 9.1 8.5e-38 130.6 9.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit SEN1_N PF12726.7 KFM76142.1 - 0.02 13.2 0.3 0.023 12.9 0.3 1.0 1 0 0 1 1 1 0 SEN1 N terminal TSC22 PF01166.18 KFM76143.1 - 1e-27 96.2 2.3 3.2e-27 94.6 2.3 1.9 1 0 0 1 1 1 1 TSC-22/dip/bun family HTH_Tnp_4 PF13613.6 KFM76144.1 - 0.00014 21.6 0.1 0.00017 21.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.16 KFM76144.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Smg4_UPF3 PF03467.15 KFM76145.1 - 3.4e-60 203.0 0.4 3.4e-60 203.0 0.4 2.7 1 1 1 2 2 2 1 Smg-4/UPF3 family RRM_2 PF04059.12 KFM76145.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif 2 Paramyxo_ncap PF00973.19 KFM76145.1 - 1.4 7.8 9.2 2 7.2 9.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein V_ATPase_I PF01496.19 KFM76145.1 - 2.1 6.1 6.9 3.1 5.6 6.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cyclin_N PF00134.23 KFM76147.1 - 1.7e-14 53.6 3.9 2.2e-13 50.0 1.2 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KFM76147.1 - 3.9e-09 36.8 0.1 1.3e-08 35.1 0.1 2.0 1 1 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 KFM76147.1 - 0.002 18.2 0.1 0.018 15.1 0.0 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 KFM76147.1 - 0.0045 17.0 0.2 0.12 12.4 0.0 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat HTH_Tnp_Tc3_2 PF01498.18 KFM76148.1 - 2.1e-16 59.9 2.2 5e-16 58.7 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76148.1 - 9.9e-14 51.3 0.0 1.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM76149.1 - 1.4e-07 31.4 0.0 1.8e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease p450 PF00067.22 KFM76150.1 - 1.6e-27 96.4 4.7 1.9e-27 96.2 4.7 1.0 1 0 0 1 1 1 1 Cytochrome P450 LANC_like PF05147.13 KFM76150.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.4 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein Ephrin_rec_like PF07699.13 KFM76151.1 - 8.4e-08 31.9 23.7 9.8e-06 25.2 6.3 7.1 3 3 4 7 7 7 6 Putative ephrin-receptor like NCD3G PF07562.14 KFM76151.1 - 0.00027 20.9 10.1 0.0023 17.8 0.8 7.2 4 3 0 7 7 7 4 Nine Cysteines Domain of family 3 GPCR VWA_2 PF13519.6 KFM76152.1 - 2e-22 79.9 0.0 1.1e-21 77.4 0.0 2.3 3 0 0 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 KFM76152.1 - 3.6e-09 35.9 24.3 0.00052 19.7 2.4 4.5 4 0 0 4 4 4 3 Ubiquitin interaction motif Ssl1 PF04056.14 KFM76152.1 - 5.6e-07 29.6 0.1 8.9e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like RAP80_UIM PF18282.1 KFM76152.1 - 0.0055 16.4 0.6 0.0055 16.4 0.6 3.7 3 1 1 4 4 4 3 RAP80 N-terminal ubiquitin interaction motif Dynamitin PF04912.14 KFM76157.1 - 2.1e-103 346.7 31.3 2.3e-103 346.5 31.3 1.0 1 0 0 1 1 1 1 Dynamitin FlxA PF14282.6 KFM76157.1 - 0.017 15.1 5.6 0.017 15.1 5.6 4.0 3 1 1 4 4 4 0 FlxA-like protein Vpu PF00558.19 KFM76157.1 - 0.056 13.2 0.5 0.056 13.2 0.5 2.3 2 0 0 2 2 2 0 Vpu protein TPR_MLP1_2 PF07926.12 KFM76157.1 - 1 9.4 35.0 0.056 13.5 3.3 4.4 3 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Hairpins PF04877.12 KFM76157.1 - 1.7 8.2 6.3 0.39 10.3 1.3 2.0 2 0 0 2 2 2 0 HrpZ adh_short PF00106.25 KFM76158.1 - 3.8e-51 173.3 0.0 4.9e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM76158.1 - 2.2e-30 105.9 0.0 2.8e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM76158.1 - 2e-13 50.6 0.0 3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFM76158.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KFM76158.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KFM76158.1 - 0.012 15.2 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TMC PF07810.13 KFM76160.1 - 7.8e-13 49.0 0.1 7.8e-13 49.0 0.1 1.6 2 1 0 2 2 2 1 TMC domain DUF3493 PF11998.8 KFM76162.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 MFS_1 PF07690.16 KFM76162.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2096 PF09869.9 KFM76162.1 - 0.037 14.1 0.3 0.049 13.7 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) TCTP PF00838.17 KFM76162.1 - 0.061 13.7 0.2 0.085 13.2 0.2 1.2 1 0 0 1 1 1 0 Translationally controlled tumour protein DDE_3 PF13358.6 KFM76163.1 - 5.2e-16 58.7 0.1 6.2e-15 55.2 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76163.1 - 7.9e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76163.1 - 0.00074 20.1 1.5 0.00074 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76163.1 - 0.0027 17.5 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76163.1 - 0.016 15.3 0.1 0.067 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM76163.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Fucokinase PF07959.12 KFM76164.1 - 2.1e-56 191.6 1.3 2.8e-56 191.2 1.3 1.1 1 0 0 1 1 1 1 L-fucokinase Fucokinase PF07959.12 KFM76165.1 - 2.6e-43 148.5 0.0 3.1e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 L-fucokinase SRAP PF02586.14 KFM76166.1 - 2.2e-30 105.9 0.0 5.3e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) HTH_Tnp_Tc3_2 PF01498.18 KFM76166.1 - 1.6e-15 57.1 6.5 2.8e-15 56.3 6.5 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76166.1 - 1.5e-14 53.9 0.0 1.2e-13 51.1 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM76166.1 - 0.0014 19.2 1.5 0.0014 19.2 1.5 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76166.1 - 0.0091 15.8 0.1 0.2 11.5 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KFM76166.1 - 0.035 14.1 1.4 0.063 13.3 0.4 1.9 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 KFM76166.1 - 0.038 14.1 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HSP20 PF00011.21 KFM76167.1 - 1.2e-18 67.1 0.0 1.8e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFM76167.1 - 5.8e-07 29.0 0.0 2.4e-06 27.0 0.0 1.9 1 1 1 2 2 2 1 HSP20-like domain found in ArsA DUF1735 PF08522.10 KFM76167.1 - 0.008 16.8 0.0 0.012 16.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1735) LPP PF04728.13 KFM76167.1 - 0.13 12.7 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Dynein_light PF01221.18 KFM76168.1 - 8.2e-24 83.7 0.2 1e-23 83.4 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4854 PF16146.5 KFM76168.1 - 0.0021 18.3 0.1 0.0024 18.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4854) DUF3109 PF11307.8 KFM76168.1 - 0.0043 16.9 0.0 0.0049 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3109) RE_LlaJI PF09563.10 KFM76168.1 - 0.032 13.4 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 LlaJI restriction endonuclease TINF2_N PF14973.6 KFM76168.1 - 0.057 13.8 0.2 0.061 13.7 0.2 1.2 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus WD40 PF00400.32 KFM76169.1 - 1.4e-28 98.5 12.1 2.8e-07 31.1 0.0 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM76169.1 - 7.6e-15 55.0 4.1 3.8e-06 27.1 0.4 4.3 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM76169.1 - 2e-05 24.6 0.1 1.6 8.6 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A ELYS-bb PF16687.5 KFM76169.1 - 0.026 13.1 0.1 0.22 10.1 0.1 2.1 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Ge1_WD40 PF16529.5 KFM76169.1 - 0.039 12.9 0.0 0.24 10.3 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFM76169.1 - 0.54 8.8 7.1 0.41 9.2 0.2 3.3 4 1 0 4 4 4 0 Nucleoporin Nup120/160 RRS1 PF04939.12 KFM76170.1 - 2.1e-53 180.5 3.5 2.1e-53 180.5 3.5 1.8 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) ATG19_autophagy PF12744.7 KFM76170.1 - 0.0022 17.2 0.7 0.0032 16.7 0.3 1.4 1 1 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding Xpo1 PF08389.12 KFM76173.1 - 4.5e-16 59.2 0.2 5.6e-14 52.4 0.2 2.5 1 1 0 1 1 1 1 Exportin 1-like protein CD20 PF04103.15 KFM76174.1 - 0.0042 17.2 17.5 0.011 15.8 17.5 1.8 1 0 0 1 1 1 1 CD20-like family 7TMR-DISM_7TM PF07695.11 KFM76174.1 - 2.4 8.0 12.1 0.26 11.2 6.6 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF2207 PF09972.9 KFM76174.1 - 4.7 5.9 5.0 42 2.7 5.0 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CDV3 PF15359.6 KFM76175.1 - 8.5e-32 110.4 14.1 8.5e-32 110.4 14.1 1.9 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 BCDHK_Adom3 PF10436.9 KFM76176.1 - 4.8e-54 182.6 1.0 6.7e-54 182.1 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFM76176.1 - 3e-12 47.0 0.0 5.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SEP PF08059.13 KFM76177.1 - 1.5e-26 92.7 0.2 4.8e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.6 KFM76177.1 - 4.4e-12 45.6 0.7 9.3e-12 44.6 0.1 1.9 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 KFM76177.1 - 9.4e-07 29.0 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 KFM76177.1 - 0.0081 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain PASTA PF03793.19 KFM76177.1 - 0.027 14.3 0.4 0.22 11.4 0.0 2.5 3 0 0 3 3 3 0 PASTA domain DUF4655 PF15548.6 KFM76177.1 - 0.47 9.4 4.6 0.35 9.8 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4655) Ribonucleas_3_3 PF14622.6 KFM76178.1 - 2.8e-43 147.1 0.2 1.5e-21 76.9 0.1 3.5 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFM76178.1 - 6e-38 129.7 4.6 5e-18 65.7 0.1 3.8 3 0 0 3 3 3 2 Ribonuclease III domain dsrm PF00035.26 KFM76178.1 - 9.2e-12 45.5 0.0 3.1e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif HLH PF00010.26 KFM76179.1 - 1.7e-17 63.1 0.3 3.3e-17 62.2 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 KFM76179.1 - 0.15 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain DUF4690 PF15756.5 KFM76179.1 - 0.43 11.2 5.1 3.5 8.3 0.1 2.5 1 1 1 2 2 2 0 Small Novel Rich in Cartilage HD-ZIP_N PF04618.12 KFM76179.1 - 8.7 6.9 10.5 1.4 9.4 6.2 2.2 2 1 0 2 2 2 0 HD-ZIP protein N terminus RBD-FIP PF09457.10 KFM76180.1 - 2.2e-14 53.1 1.1 2.2e-14 53.1 1.1 5.6 7 0 0 7 7 6 1 FIP domain CENP-H PF05837.12 KFM76180.1 - 6.4e-05 23.3 45.2 0.057 13.8 5.7 3.6 1 1 1 3 3 3 3 Centromere protein H (CENP-H) HAUS-augmin3 PF14932.6 KFM76180.1 - 0.00032 20.4 9.0 0.00032 20.4 9.0 3.6 1 1 2 3 3 3 1 HAUS augmin-like complex subunit 3 BRI3BP PF14965.6 KFM76180.1 - 0.0044 16.5 1.8 0.044 13.3 0.7 2.4 2 0 0 2 2 2 1 Negative regulator of p53/TP53 ZapB PF06005.12 KFM76180.1 - 0.011 16.2 10.9 0.011 16.2 10.9 5.4 3 3 2 5 5 5 0 Cell division protein ZapB CDPS PF16715.5 KFM76180.1 - 0.015 14.9 1.2 0.015 14.9 1.2 2.8 1 1 2 3 3 3 0 Cyclodipeptide synthase UPF0242 PF06785.11 KFM76180.1 - 0.02 15.0 54.7 0.02 15.0 14.9 3.4 1 1 2 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KFM76180.1 - 0.024 14.5 3.9 0.024 14.5 3.9 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 KFM76180.1 - 0.042 11.4 37.7 0.049 11.1 17.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) HALZ PF02183.18 KFM76180.1 - 0.075 13.3 1.1 0.075 13.3 1.1 6.7 6 1 2 8 8 7 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 KFM76180.1 - 0.12 12.4 0.2 0.12 12.4 0.2 7.0 6 1 1 7 7 7 0 Basic region leucine zipper DUF5082 PF16888.5 KFM76180.1 - 0.5 10.7 29.3 0.061 13.6 16.3 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 KFM76180.1 - 0.58 10.7 27.9 25 5.4 17.5 4.9 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 KFM76180.1 - 0.69 9.4 34.9 0.68 9.4 14.8 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Nup54 PF13874.6 KFM76180.1 - 0.75 9.9 34.8 0.3 11.2 9.8 3.3 1 1 1 3 3 3 0 Nucleoporin complex subunit 54 EzrA PF06160.12 KFM76180.1 - 0.96 7.5 39.6 0.018 13.2 29.4 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF3450 PF11932.8 KFM76180.1 - 2 7.6 39.6 0.065 12.5 8.4 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) FlxA PF14282.6 KFM76180.1 - 2.3 8.2 42.4 0.062 13.3 14.4 4.1 1 1 2 4 4 4 0 FlxA-like protein FUSC PF04632.12 KFM76180.1 - 2.4 6.6 18.1 0.096 11.2 10.4 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Spc7 PF08317.11 KFM76180.1 - 3.2 6.5 51.8 0.28 10.0 12.4 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein APG6_N PF17675.1 KFM76180.1 - 4.4 7.8 57.2 1.2 9.6 16.3 3.6 1 1 3 4 4 4 0 Apg6 coiled-coil region ATG16 PF08614.11 KFM76180.1 - 4.8 7.4 49.8 0.72 10.0 10.3 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF4472 PF14739.6 KFM76180.1 - 5.1 7.9 41.3 0.48 11.2 14.3 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Vac_Fusion PF02346.16 KFM76180.1 - 7.1 6.3 15.3 0.92 9.2 0.2 4.7 3 1 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 DUF4407 PF14362.6 KFM76180.1 - 7.5 5.8 30.1 1.5 8.1 11.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KFM76180.1 - 8 6.3 42.7 1.9 8.3 4.5 6.0 4 2 1 5 5 5 0 Septum formation initiator YabA PF06156.13 KFM76180.1 - 9.4 6.9 43.1 7.9 7.2 11.2 4.1 1 1 1 3 3 3 0 Initiation control protein YabA LPP PF04728.13 KFM76180.1 - 9.7 6.7 15.5 4.5 7.7 3.3 4.1 3 2 1 4 4 4 0 Lipoprotein leucine-zipper RNase_PH PF01138.21 KFM76181.1 - 5.6e-34 117.5 0.1 7.1e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFM76181.1 - 0.001 19.1 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 IBN_N PF03810.19 KFM76182.1 - 1.7e-17 63.1 1.3 1.3e-15 57.0 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 KFM76182.1 - 3e-05 23.0 3.0 3e-05 23.0 3.0 2.3 2 1 0 3 3 3 1 Cse1 Xpo1 PF08389.12 KFM76182.1 - 8.8e-05 22.6 7.3 0.00042 20.4 0.4 4.0 4 0 0 4 4 4 1 Exportin 1-like protein RTP1_C1 PF10363.9 KFM76182.1 - 0.003 17.7 0.7 0.14 12.4 0.2 3.9 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF1823 PF08853.11 KFM76182.1 - 0.087 13.0 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) RRF_GI PF12614.8 KFM76182.1 - 0.11 12.7 0.9 0.3 11.2 0.9 1.7 1 0 0 1 1 1 0 Ribosome recycling factor NAD_binding_4 PF07993.12 KFM76183.1 - 1.5e-63 214.4 0.0 2.4e-45 154.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KFM76183.1 - 2.2e-08 33.4 0.2 0.0037 16.3 0.1 3.1 3 1 0 4 4 4 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFM76183.1 - 1.7e-07 31.0 0.0 0.02 14.3 0.0 2.9 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFM76183.1 - 1.5e-06 27.5 0.1 0.023 13.8 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFM76183.1 - 2.4e-05 23.9 0.0 0.038 13.4 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFM76183.1 - 0.011 14.8 0.1 0.71 8.9 0.0 2.4 3 0 0 3 3 3 0 RmlD substrate binding domain KR PF08659.10 KFM76183.1 - 0.016 15.2 0.0 0.089 12.7 0.0 2.1 2 0 0 2 2 2 0 KR domain Semialdhyde_dh PF01118.24 KFM76183.1 - 0.027 14.9 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KFM76183.1 - 0.19 11.6 0.0 26 4.7 0.0 3.0 2 1 0 2 2 2 0 NAD(P)H-binding DUF5641 PF18701.1 KFM76184.1 - 7.5e-24 83.7 0.2 1.5e-23 82.8 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1759 PF03564.15 KFM76184.1 - 9.7e-15 54.8 1.0 2.3e-14 53.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM76184.1 - 0.0039 17.0 0.0 0.0091 15.8 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Toxin_13 PF07822.11 KFM76184.1 - 0.03 14.4 0.1 0.098 12.8 0.1 1.8 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein NAD_binding_4 PF07993.12 KFM76185.1 - 1.5e-06 27.6 0.0 2.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 KFM76185.1 - 0.019 15.2 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein DDE_1 PF03184.19 KFM76186.1 - 4e-18 65.7 0.2 5.7e-18 65.2 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease 40S_SA_C PF16122.5 KFM76188.1 - 4.6e-07 31.1 1.0 5.5e-07 30.9 1.0 1.2 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus HTH_38 PF13936.6 KFM76188.1 - 0.055 13.2 0.2 0.085 12.6 0.2 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Symplekin_C PF12295.8 KFM76189.1 - 7.3e-70 234.8 8.0 1.3e-69 234.0 6.6 2.2 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KFM76189.1 - 5e-54 183.3 3.3 5e-54 183.3 3.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) DUF3385 PF11865.8 KFM76189.1 - 0.0032 17.4 1.1 0.31 10.9 0.1 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 KFM76189.1 - 0.042 13.6 0.8 0.9 9.2 0.2 3.2 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis LIN37 PF15306.6 KFM76189.1 - 0.86 9.8 2.9 4.6 7.5 0.0 3.1 3 0 0 3 3 3 0 LIN37 Ras PF00071.22 KFM76190.1 - 1e-15 57.7 0.1 1.1e-15 57.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM76190.1 - 1e-07 32.2 0.0 1.1e-07 32.1 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFM76190.1 - 0.0093 16.4 0.0 0.0095 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KFM76190.1 - 0.014 15.4 0.1 0.015 15.3 0.1 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KFM76190.1 - 0.022 15.0 0.0 0.024 14.9 0.0 1.0 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KFM76190.1 - 0.025 14.0 0.0 0.025 14.0 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 KFM76190.1 - 0.032 14.0 0.0 0.035 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM76190.1 - 0.041 13.8 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 KFM76190.1 - 0.1 12.5 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KFM76190.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFM76190.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFM76190.1 - 0.19 11.3 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Gal-3-0_sulfotr PF06990.11 KFM76191.1 - 6.4e-76 255.8 0.3 8e-76 255.5 0.3 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 KFM76191.1 - 6.5e-08 32.8 0.1 1.4e-06 28.4 0.1 2.3 1 1 0 1 1 1 1 Sulfotransferase family DEAD PF00270.29 KFM76192.1 - 7.8e-52 175.6 0.0 2.9e-51 173.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM76192.1 - 8.7e-30 103.3 0.0 7.4e-29 100.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Pribosyltran PF00156.27 KFM76195.1 - 6.5e-22 77.7 0.2 8.3e-22 77.4 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFM76195.1 - 0.032 13.7 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KFM76195.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase FERM_C PF09380.10 KFM76196.1 - 2.6e-23 82.2 0.0 5.5e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFM76196.1 - 9.5e-21 74.4 0.5 3.1e-20 72.7 0.1 2.0 2 0 0 2 2 2 1 FERM central domain FA PF08736.11 KFM76196.1 - 3.4e-13 49.4 13.1 6.1e-13 48.6 13.1 1.4 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 KFM76196.1 - 1.4e-11 44.1 0.1 4.6e-11 42.5 0.1 1.9 1 0 0 1 1 1 1 FERM N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM76197.1 - 2e-16 60.0 2.2 4.2e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76197.1 - 9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease EMC3_TMCO1 PF01956.16 KFM76198.1 - 0.37 10.5 2.5 0.4 10.4 2.5 1.0 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF1213 PF06740.12 KFM76198.1 - 1.2 9.8 5.2 5.6 7.6 5.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1213) Pkinase PF00069.25 KFM76200.1 - 5.4e-32 111.2 0.2 6.2e-32 111.0 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM76200.1 - 2e-23 83.0 0.1 2.1e-23 82.9 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM76200.1 - 6.7e-05 22.0 0.1 7.3e-05 21.9 0.1 1.0 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM76200.1 - 0.00032 20.1 0.1 0.00054 19.4 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM76200.1 - 0.035 14.0 0.0 0.23 11.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM76200.1 - 0.055 12.8 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF309 PF03745.14 KFM76200.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Gln_deamidase_2 PF18626.1 KFM76200.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutaminase Phage_int_SAM_5 PF13102.6 KFM76200.1 - 0.11 12.9 0.1 0.14 12.5 0.1 1.1 1 0 0 1 1 1 0 Phage integrase SAM-like domain SURF1 PF02104.15 KFM76201.1 - 4e-42 144.4 0.0 5.1e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 SURF1 family Smim3 PF17307.2 KFM76201.1 - 0.061 12.8 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Small integral membrane protein 3 Innexin PF00876.18 KFM76202.1 - 4.5e-92 309.0 4.6 5.3e-92 308.8 4.6 1.0 1 0 0 1 1 1 1 Innexin DDE_1 PF03184.19 KFM76205.1 - 1.9e-08 34.2 0.1 2.7e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM76205.1 - 0.00024 20.9 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease EF-hand_13 PF17958.1 KFM76205.1 - 0.091 12.6 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain Exo_endo_phos_2 PF14529.6 KFM76206.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Mgm101p PF06420.12 KFM76207.1 - 0.078 12.5 0.2 0.11 12.1 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 DDE_3 PF13358.6 KFM76209.1 - 8.4e-05 22.4 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KFM76211.1 - 4.6e-05 23.2 0.0 7.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease BrkDBD PF09607.10 KFM76211.1 - 0.00014 21.6 1.6 0.00076 19.2 1.2 2.4 2 1 0 2 2 2 1 Brinker DNA-binding domain HTH_Tnp_Tc5 PF03221.16 KFM76211.1 - 0.00018 21.5 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM76211.1 - 0.013 15.1 1.1 0.013 15.1 1.1 2.0 2 1 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Transglut_core2 PF13369.6 KFM76211.1 - 0.071 12.7 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily HTH_Tnp_Tc3_2 PF01498.18 KFM76212.1 - 2.2e-16 59.8 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76212.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease IRF PF00605.17 KFM76213.1 - 1.4e-15 57.4 2.4 8.6e-15 54.9 0.6 2.4 2 0 0 2 2 2 1 Interferon regulatory factor transcription factor Ets PF00178.22 KFM76213.1 - 0.00056 20.3 1.2 0.0012 19.3 0.2 2.2 2 0 0 2 2 2 1 Ets-domain SLATT_5 PF18160.1 KFM76213.1 - 0.17 11.2 1.3 0.21 10.9 0.1 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 zf-C3Hc3H PF13891.6 KFM76214.1 - 1.5e-16 60.5 2.6 2.3e-16 59.9 2.6 1.3 1 0 0 1 1 1 1 Potential DNA-binding domain WRC PF08879.10 KFM76214.1 - 0.036 13.7 1.2 6.8 6.5 0.2 2.3 2 0 0 2 2 2 0 WRC CD20 PF04103.15 KFM76215.1 - 1.1e-06 28.9 4.9 1.1e-06 28.9 4.9 1.8 1 1 1 2 2 2 1 CD20-like family Reticulon PF02453.17 KFM76215.1 - 0.45 10.5 5.8 0.45 10.5 3.7 2.1 1 1 0 1 1 1 0 Reticulon SIL1 PF16782.5 KFM76216.1 - 3.5e-11 42.9 3.0 5e-11 42.3 2.5 1.5 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 Arm PF00514.23 KFM76216.1 - 0.0036 17.3 0.2 1.1 9.5 0.1 3.1 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat ALIX_LYPXL_bnd PF13949.6 KFM76216.1 - 0.03 13.6 3.5 0.021 14.1 0.7 1.9 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF4704 PF15787.5 KFM76216.1 - 0.051 12.8 4.6 0.13 11.5 2.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4704) SRP1_TIP1 PF00660.17 KFM76216.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Seripauperin and TIP1 family THAP PF05485.12 KFM76217.1 - 2.8e-07 31.4 0.1 2.8e-07 31.4 0.1 1.0 1 0 0 1 1 1 1 THAP domain GFO_IDH_MocA PF01408.22 KFM76218.1 - 5.4e-05 24.0 0.2 6.8e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF4926 PF16277.5 KFM76218.1 - 0.16 11.4 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) RRM_1 PF00076.22 KFM76220.1 - 7.4e-38 128.2 0.0 6e-20 70.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM76220.1 - 5.4e-05 23.2 0.1 0.19 11.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif DUF737 PF05300.11 KFM76220.1 - 0.0064 16.9 0.5 0.98 9.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF737) LRRC37AB_C PF14914.6 KFM76220.1 - 0.032 14.1 0.4 0.032 14.1 0.4 1.8 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain RRM_occluded PF16842.5 KFM76220.1 - 0.056 13.3 0.0 0.79 9.6 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_1 PF00076.22 KFM76221.1 - 0.0004 20.2 0.0 0.00087 19.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_Tnp_Tc3_2 PF01498.18 KFM76222.1 - 8e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76222.1 - 1.2e-14 54.3 0.1 1.3e-13 50.9 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM76222.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76222.1 - 0.012 15.4 0.1 0.56 10.1 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain CUB PF00431.20 KFM76223.1 - 2.6e-12 47.0 0.0 6.5e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 CUB domain SVA PF05326.11 KFM76223.1 - 0.0039 17.2 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Seminal vesicle autoantigen (SVA) Forkhead PF00250.18 KFM76226.1 - 7.3e-15 55.0 0.7 3.4e-14 52.8 0.2 1.9 1 1 1 2 2 2 1 Forkhead domain Ax_dynein_light PF10211.9 KFM76226.1 - 0.058 13.3 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain FOXP-CC PF16159.5 KFM76227.1 - 1.7e-15 57.4 0.6 1.7e-15 57.4 0.6 4.0 2 1 1 3 3 3 1 FOXP coiled-coil domain TPR_MLP1_2 PF07926.12 KFM76227.1 - 0.0018 18.4 17.4 0.0032 17.5 17.4 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Coatomer_b_Cpla PF14806.6 KFM76227.1 - 0.041 13.9 2.3 3.4 7.6 2.3 2.5 1 1 0 1 1 1 0 Coatomer beta subunit appendage platform DUF5347 PF17282.2 KFM76227.1 - 0.24 11.7 3.9 0.4 11.0 3.7 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5347) GNAT_acetyltran PF12746.7 KFM76227.1 - 0.31 10.6 3.3 0.33 10.5 2.5 1.4 1 1 0 1 1 1 0 GNAT acetyltransferase Paralemmin PF03285.15 KFM76227.1 - 0.38 10.3 11.3 0.48 10.0 10.7 1.6 1 1 0 1 1 1 0 Paralemmin YhdB PF14148.6 KFM76227.1 - 0.81 9.8 3.8 0.35 11.0 0.7 1.9 2 0 0 2 2 2 0 YhdB-like protein Exonuc_VII_L PF02601.15 KFM76227.1 - 1.6 8.3 15.1 2 7.9 15.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 KFM76227.1 - 2.2 8.8 24.1 28 5.3 0.1 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 KFM76227.1 - 3.5 6.1 7.8 4.4 5.8 7.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Homeodomain PF00046.29 KFM76228.1 - 8.9e-21 73.5 2.1 1.8e-20 72.5 2.1 1.5 1 0 0 1 1 1 1 Homeodomain AIG1 PF04548.16 KFM76228.1 - 0.012 14.9 0.3 0.019 14.3 0.3 1.2 1 0 0 1 1 1 0 AIG1 family Homeobox_KN PF05920.11 KFM76228.1 - 0.017 15.0 0.1 0.017 15.0 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain TPIP1 PF15338.6 KFM76229.1 - 0.054 13.6 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 Ribosomal_L28 PF00830.19 KFM76230.1 - 0.0038 17.4 0.0 0.0077 16.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L28 family mRNA_cap_enzyme PF01331.19 KFM76232.1 - 0.032 14.1 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain BHD_1 PF10403.9 KFM76232.1 - 0.066 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 DUF1116 PF06545.11 KFM76232.1 - 0.085 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) FtsJ PF01728.19 KFM76233.1 - 7e-21 75.1 0.1 1.1e-20 74.5 0.0 1.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase SNF PF00209.18 KFM76233.1 - 0.083 11.6 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family G-patch PF01585.23 KFM76234.1 - 7.3e-15 54.6 5.4 1.5e-14 53.6 5.4 1.5 1 0 0 1 1 1 1 G-patch domain FtsJ PF01728.19 KFM76234.1 - 9.3e-09 35.6 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch_2 PF12656.7 KFM76234.1 - 0.00039 20.4 2.3 0.00091 19.3 2.3 1.6 1 0 0 1 1 1 1 G-patch domain DIE2_ALG10 PF04922.12 KFM76235.1 - 4.3e-51 174.4 7.0 6.4e-51 173.9 7.0 1.3 1 0 0 1 1 1 1 DIE2/ALG10 family 7tm_1 PF00001.21 KFM76241.1 - 6.3e-26 91.3 6.1 8.1e-26 90.9 6.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM76241.1 - 2.2e-08 34.0 2.0 2.2e-08 34.0 2.0 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFM76241.1 - 3.2e-07 30.0 5.3 4e-07 29.7 5.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFM76241.1 - 1.7e-05 24.3 5.7 3.3e-05 23.4 5.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFM76241.1 - 0.00017 21.0 1.3 0.00017 21.0 1.3 1.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw Frag1 PF10277.9 KFM76241.1 - 0.00057 19.5 6.9 0.0044 16.6 0.9 2.1 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family Srg PF02118.21 KFM76241.1 - 0.0053 16.5 2.8 0.0053 16.5 2.8 2.1 2 0 0 2 2 2 1 Srg family chemoreceptor 7TM_GPCR_Srt PF10321.9 KFM76241.1 - 0.0053 15.8 0.4 0.0053 15.8 0.4 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srt DUF3413 PF11893.8 KFM76241.1 - 0.017 14.3 3.0 0.97 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) DUF1673 PF07895.11 KFM76241.1 - 0.057 13.1 0.1 0.057 13.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) 7tm_4 PF13853.6 KFM76241.1 - 0.12 12.1 9.2 0.088 12.5 0.5 2.9 2 1 0 2 2 2 0 Olfactory receptor HTH_Tnp_Tc3_2 PF01498.18 KFM76242.1 - 3.6e-09 36.7 0.0 4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Transposase EF-hand_1 PF00036.32 KFM76245.1 - 0.0012 18.3 0.2 0.0047 16.4 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFM76245.1 - 0.0043 16.9 0.1 0.048 13.6 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KFM76245.1 - 0.018 15.5 0.2 0.073 13.5 0.2 1.9 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KFM76245.1 - 0.047 13.2 0.1 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 EF hand MH2 PF03166.14 KFM76247.1 - 9.6e-51 172.7 0.0 1.5e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFM76247.1 - 4.4e-22 78.2 0.4 1.5e-21 76.6 0.1 2.0 2 0 0 2 2 2 1 MH1 domain Transcrip_reg PF01709.20 KFM76247.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator LRR_8 PF13855.6 KFM76251.1 - 2e-23 81.9 8.0 4.7e-13 48.7 0.5 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM76251.1 - 2.2e-12 47.0 5.5 4.7e-06 26.9 0.9 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM76251.1 - 2.5e-09 36.4 9.8 0.34 11.6 0.1 6.4 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 KFM76251.1 - 0.00025 20.9 2.8 3.2 8.0 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 KFM76251.1 - 0.0004 19.9 0.4 0.016 14.7 0.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFM76251.1 - 0.00052 20.0 0.8 0.0013 18.7 0.1 2.1 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) HTH_Tnp_Tc3_2 PF01498.18 KFM76252.1 - 4.4e-11 42.9 0.0 5.3e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Transposase PRD1_DD PF11087.8 KFM76252.1 - 0.037 13.7 0.1 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery LRR_8 PF13855.6 KFM76253.1 - 2.1e-06 27.4 0.1 3.4e-05 23.5 0.2 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM76253.1 - 0.0012 19.2 0.7 0.0049 17.3 0.1 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM76253.1 - 0.039 13.9 0.1 0.063 13.3 0.1 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM76253.1 - 0.14 12.8 3.9 4.8 8.1 0.1 4.0 4 1 0 4 4 4 0 Leucine Rich Repeat DUF3502 PF12010.8 KFM76254.1 - 0.015 15.9 2.1 0.018 15.7 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) KxDL PF10241.9 KFM76254.1 - 0.048 13.9 2.1 0.11 12.7 2.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein CENP-H PF05837.12 KFM76254.1 - 0.28 11.6 7.0 0.3 11.5 7.0 1.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4337 PF14235.6 KFM76254.1 - 0.67 10.1 7.2 0.76 9.9 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3886 PF13025.6 KFM76254.1 - 2.5 8.3 13.6 0.15 12.3 6.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) Mto2_bdg PF12808.7 KFM76254.1 - 3.6 8.0 8.9 36 4.8 3.0 3.1 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region W2 PF02020.18 KFM76255.1 - 1.1e-15 57.6 0.4 3.6e-14 52.7 0.2 2.7 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KFM76255.1 - 1.6e-13 49.8 16.8 3.3e-06 26.6 6.8 4.5 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM76255.1 - 1.5e-07 31.0 11.7 0.00014 21.5 0.0 4.1 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFM76255.1 - 1.1e-05 23.8 0.5 2e-05 23.0 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 KFM76255.1 - 0.0014 18.3 0.0 0.0066 16.1 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyl transferase Fucokinase PF07959.12 KFM76255.1 - 0.024 13.6 0.3 0.024 13.6 0.3 2.6 3 0 0 3 3 3 0 L-fucokinase PTCB-BRCT PF12738.7 KFM76256.1 - 3.2e-63 209.5 5.3 5.7e-18 64.6 0.0 7.1 7 1 0 7 7 7 5 twin BRCT domain BRCT PF00533.26 KFM76256.1 - 4.8e-53 177.5 8.2 7.8e-11 42.2 0.0 7.5 7 0 0 7 7 7 6 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFM76256.1 - 6.7e-30 103.3 9.8 1.1e-05 25.7 0.0 7.9 7 1 1 8 8 8 6 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFM76256.1 - 3.6e-11 43.2 0.1 1.3 9.3 0.0 5.5 5 0 0 5 5 5 4 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KFM76256.1 - 6.6e-06 25.9 0.0 1.8 8.5 0.0 5.3 5 0 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KFM76256.1 - 0.014 15.4 0.0 2.5 8.2 0.0 3.5 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 KFM76257.1 - 2.7e-11 43.7 0.4 8.5e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFM76257.1 - 5.4e-05 23.5 0.0 0.0033 17.8 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFM76257.1 - 9.5e-05 22.2 0.1 0.0024 17.7 0.0 2.3 2 1 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KFM76257.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Glyco_hydro_16 PF00722.21 KFM76257.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 Complex1_30kDa PF00329.19 KFM76262.1 - 7.5e-44 149.3 0.0 1.1e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit ArsR PF09824.9 KFM76264.1 - 0.057 13.0 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator Pneumo_ncap PF03246.13 KFM76265.1 - 0.027 13.2 0.1 0.027 13.2 0.1 1.0 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein FTA2 PF13095.6 KFM76267.1 - 0.053 13.1 0.1 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF547 PF04784.14 KFM76269.1 - 6.3e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 ArlS_N PF18719.1 KFM76270.1 - 0.31 11.3 1.8 0.82 9.9 0.8 2.1 3 0 0 3 3 3 0 ArlS sensor domain HIT PF01230.23 KFM76272.1 - 0.073 13.8 2.0 5 7.9 2.0 2.4 1 1 0 1 1 1 0 HIT domain DUF3817 PF12823.7 KFM76273.1 - 0.013 16.3 0.0 0.019 15.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) Trypsin PF00089.26 KFM76274.1 - 2.4e-22 79.9 0.2 2.6e-22 79.7 0.2 1.0 1 0 0 1 1 1 1 Trypsin Toxin_21 PF08091.11 KFM76275.1 - 1.7 8.6 5.5 0.16 11.9 0.7 1.8 2 0 0 2 2 2 0 Spider insecticidal peptide Glyco_transf_7N PF13733.6 KFM76276.1 - 1.3e-47 160.8 0.0 1.9e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFM76276.1 - 4.9e-28 96.6 0.2 2.9e-26 90.9 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFM76276.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 CHGN PF05679.16 KFM76276.1 - 0.16 10.8 0.1 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Chondroitin N-acetylgalactosaminyltransferase WD40 PF00400.32 KFM76277.1 - 3.4e-23 81.5 6.0 9.1e-06 26.3 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_3 PF13570.6 KFM76277.1 - 1.6e-06 28.4 0.5 0.31 11.6 0.0 4.0 4 1 1 5 5 5 2 PQQ-like domain Nucleoporin_N PF08801.11 KFM76277.1 - 0.003 16.4 0.0 1 8.0 0.0 2.6 1 1 2 3 3 3 2 Nup133 N terminal like PCMD PF13201.6 KFM76277.1 - 0.055 13.3 0.0 0.29 10.9 0.0 1.9 1 1 1 2 2 2 0 Putative carbohydrate metabolism domain WD40_like PF17005.5 KFM76277.1 - 0.095 12.0 0.0 5.3 6.3 0.0 2.2 1 1 0 2 2 2 0 WD40-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM76280.1 - 4.4e-16 58.9 3.5 5.8e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76280.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76280.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76280.1 - 0.0027 17.5 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76280.1 - 2.4 8.8 15.6 0.12 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HMG_box PF00505.19 KFM76282.1 - 0.016 15.6 0.2 0.039 14.4 0.2 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box Elf4 PF07011.11 KFM76282.1 - 0.037 13.9 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Early Flowering 4 domain HIP1_clath_bdg PF16515.5 KFM76282.1 - 0.059 14.0 0.6 0.059 14.0 0.6 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SOG2 PF10428.9 KFM76282.1 - 0.21 10.8 23.0 0.26 10.5 23.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 KFM76282.1 - 1.2 7.6 23.4 2.3 6.7 23.4 1.4 1 0 0 1 1 1 0 Macoilin family DUF5521 PF17659.1 KFM76282.1 - 5.3 4.7 10.9 6.2 4.5 10.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) adh_short PF00106.25 KFM76283.1 - 3.7e-36 124.4 0.0 2.5e-35 121.7 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM76283.1 - 4.9e-24 85.2 0.0 2.4e-23 82.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM76283.1 - 4.3e-08 33.3 0.1 8e-08 32.4 0.1 1.5 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KFM76283.1 - 1.3e-05 24.8 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFM76283.1 - 5.1e-05 23.2 0.0 8.3e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFM76283.1 - 0.00037 20.7 0.1 0.0015 18.8 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 KFM76283.1 - 0.0038 16.5 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFM76283.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFM76283.1 - 0.036 13.2 0.1 0.84 8.7 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PTN_MK_C PF01091.18 KFM76283.1 - 0.037 14.4 1.4 0.084 13.3 0.7 1.9 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain Shikimate_DH PF01488.20 KFM76283.1 - 0.047 13.8 0.7 0.13 12.3 0.3 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.8 KFM76283.1 - 0.057 13.2 0.4 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.16 KFM76283.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 KFM76283.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Wax2_C PF12076.8 KFM76283.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain Stealth_CR3 PF17102.5 KFM76284.1 - 1.6e-15 56.7 4.3 3e-15 55.8 4.3 1.5 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 EF-hand_6 PF13405.6 KFM76284.1 - 9.1e-06 25.2 0.1 3.4e-05 23.4 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KFM76284.1 - 0.0028 17.1 0.1 0.0058 16.1 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFM76284.1 - 0.0087 16.5 0.1 0.024 15.1 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair DMAP_binding PF06464.11 KFM76284.1 - 0.1 13.4 1.6 0.14 13.0 0.2 2.0 1 1 1 2 2 2 0 DMAP1-binding Domain Notch PF00066.17 KFM76285.1 - 8.2e-17 61.4 35.1 5.9e-10 39.4 12.2 2.2 2 0 0 2 2 2 2 LNR domain GlcNAc-1_reg PF18440.1 KFM76286.1 - 1.6e-11 44.2 1.9 1.7e-10 41.0 0.8 2.1 2 0 0 2 2 2 1 Putative GlcNAc-1 phosphotransferase regulatory domain BRAP2 PF07576.12 KFM76286.1 - 0.056 13.7 0.4 6.1 7.1 0.1 2.2 2 0 0 2 2 2 0 BRCA1-associated protein 2 GAT PF03127.14 KFM76286.1 - 0.11 12.8 0.5 0.17 12.2 0.5 1.3 1 0 0 1 1 1 0 GAT domain HTH_Tnp_Tc3_2 PF01498.18 KFM76288.1 - 6e-16 58.4 2.2 6e-16 58.4 2.2 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.6 KFM76288.1 - 1.3e-13 51.0 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76288.1 - 2.2e-07 30.5 1.2 7.4e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76288.1 - 0.0027 17.5 0.6 0.008 16.0 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76288.1 - 0.095 12.8 0.4 0.095 12.8 0.4 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain zf-H2C2_2 PF13465.6 KFM76289.1 - 2.9e-51 169.7 54.1 1.5e-08 34.7 0.7 10.0 9 1 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76289.1 - 3.1e-30 102.9 68.7 6.4e-06 26.3 2.1 9.3 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76289.1 - 1.8e-20 71.9 66.3 0.0011 19.6 0.3 9.4 10 0 0 10 10 9 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM76289.1 - 4.1e-08 33.0 51.6 0.019 14.9 0.0 10.3 9 1 0 9 9 9 4 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM76289.1 - 1.4e-06 28.2 25.8 0.2 11.7 0.2 8.8 7 2 2 9 9 9 2 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM76289.1 - 0.00047 20.0 32.1 0.53 10.3 0.7 8.0 9 0 0 9 9 9 3 zinc-finger of a C2HC-type Baculo_IE-1 PF05290.11 KFM76289.1 - 0.0013 18.6 24.5 0.98 9.4 8.7 6.3 1 1 3 4 4 4 1 Baculovirus immediate-early protein (IE-0) BolA PF01722.18 KFM76289.1 - 0.0039 17.4 3.8 2.2 8.6 0.0 3.8 3 1 0 4 4 4 2 BolA-like protein zf-met PF12874.7 KFM76289.1 - 0.024 15.0 0.4 0.024 15.0 0.4 9.7 10 1 1 11 11 10 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 KFM76289.1 - 0.024 15.4 25.9 0.45 11.3 1.0 4.7 1 1 1 4 4 4 0 zinc-ribbon family zf-C2H2_11 PF16622.5 KFM76289.1 - 0.057 13.2 0.2 0.057 13.2 0.2 6.9 8 0 0 8 8 8 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KFM76289.1 - 0.33 10.6 27.0 4.9 6.8 0.0 7.6 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KFM76289.1 - 1.1 9.1 13.6 3.7 7.4 1.1 4.8 1 1 5 6 6 6 0 GAGA factor Ta0938 PF11494.8 KFM76289.1 - 1.1 9.6 18.2 7.3 6.9 0.4 5.2 1 1 5 6 6 6 0 Ta0938 zf-C2H2_2 PF12756.7 KFM76289.1 - 1.3 9.4 39.0 0.3 11.5 0.5 6.2 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFM76289.1 - 1.9 8.9 48.0 1.4 9.3 1.2 9.0 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 KFM76289.1 - 2.8 8.2 43.0 6.1 7.1 0.3 8.9 8 2 1 9 9 9 0 AN1-like Zinc finger zf-C2H2_3rep PF18868.1 KFM76289.1 - 3.3 8.4 24.9 0.77 10.5 0.7 5.6 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats DUF4764 PF15961.5 KFM76289.1 - 4.5 5.8 10.6 0.25 10.0 1.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4764) zf-MYST PF17772.1 KFM76289.1 - 7.7 6.2 30.3 6.4 6.5 0.2 6.6 4 4 3 7 7 7 0 MYST family zinc finger domain Cystatin PF00031.21 KFM76291.1 - 0.16 12.3 3.8 1.2 9.5 1.7 2.1 1 1 1 2 2 2 0 Cystatin domain RVT_1 PF00078.27 KFM76292.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 KFM76293.1 - 6.3e-07 29.3 0.0 6.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PHF5 PF03660.14 KFM76295.1 - 0.059 13.6 1.4 0.085 13.1 1.4 1.3 1 0 0 1 1 1 0 PHF5-like protein zf-H2C2_2 PF13465.6 KFM76296.1 - 2.4e-62 204.8 74.1 7.1e-09 35.7 0.2 11.1 10 1 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76296.1 - 3.4e-34 115.4 89.0 5.6e-05 23.4 3.0 10.9 11 0 0 11 11 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76296.1 - 2.3e-29 99.5 79.0 0.0011 19.7 2.1 10.4 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM76296.1 - 1e-15 57.3 65.9 0.08 13.0 1.2 11.1 10 0 0 10 10 10 8 C2H2-type zinc finger zf-met PF12874.7 KFM76296.1 - 2e-11 43.9 69.8 0.19 12.1 0.9 11.0 10 1 0 10 10 10 7 Zinc-finger of C2H2 type BolA PF01722.18 KFM76296.1 - 6.9e-11 42.3 9.8 0.41 11.0 0.1 6.6 3 2 4 7 7 7 4 BolA-like protein zf-C2H2_jaz PF12171.8 KFM76296.1 - 1.4e-09 37.9 60.9 0.41 11.0 0.1 10.6 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM76296.1 - 0.0024 17.6 49.0 0.039 13.7 0.9 9.1 9 0 0 9 9 9 5 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM76296.1 - 0.0057 16.5 44.3 0.79 9.7 0.1 10.1 10 0 0 10 10 10 2 zinc-finger of a C2HC-type GAGA PF09237.11 KFM76296.1 - 0.053 13.3 17.2 0.12 12.2 0.1 6.3 3 2 4 7 7 7 0 GAGA factor zf_UBZ PF18439.1 KFM76296.1 - 0.08 12.6 39.1 2.5 7.8 0.1 9.7 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger BHD_1 PF10403.9 KFM76296.1 - 0.11 12.3 1.1 30 4.5 0.1 4.0 3 1 0 3 3 3 0 Rad4 beta-hairpin domain 1 Zn-ribbon_8 PF09723.10 KFM76296.1 - 0.13 12.4 0.3 0.13 12.4 0.3 6.8 4 1 4 8 8 8 0 Zinc ribbon domain DUF3268 PF11672.8 KFM76296.1 - 0.35 11.2 0.2 0.35 11.2 0.2 4.7 5 2 0 5 5 5 0 zinc-finger-containing domain FYVE PF01363.21 KFM76296.1 - 0.41 10.8 56.5 3.2 8.0 7.7 7.1 2 1 3 6 6 6 0 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 KFM76296.1 - 2.2 8.4 34.8 8.5 6.5 0.3 9.2 9 2 1 10 10 10 0 Sec23/Sec24 zinc finger zf-FCS PF06467.14 KFM76296.1 - 8.2 6.5 50.2 7.2 6.6 0.3 9.5 7 2 2 9 9 9 0 MYM-type Zinc finger with FCS sequence motif MutS_II PF05188.17 KFM76297.1 - 4e-06 27.1 0.0 6.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KFM76299.1 - 7.1e-19 68.0 2.3 7.1e-19 68.0 2.3 2.1 2 0 0 2 2 2 1 MutS family domain IV MutS_III PF05192.18 KFM76299.1 - 9.1e-14 52.1 4.0 1.5e-13 51.4 4.0 1.3 1 0 0 1 1 1 1 MutS domain III DUF2452 PF10504.9 KFM76299.1 - 0.0015 18.0 0.2 0.0034 16.9 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2452) Glyco_hydro_57 PF03065.15 KFM76299.1 - 0.0032 16.7 0.2 0.0078 15.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DrrA_P4M PF14860.6 KFM76299.1 - 0.057 13.3 3.8 0.046 13.6 1.1 2.4 2 2 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Ntox47 PF15540.6 KFM76299.1 - 0.072 13.4 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial toxin 47 DUF4715 PF15835.5 KFM76299.1 - 0.082 13.0 0.8 2.5 8.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4715) DUF4407 PF14362.6 KFM76299.1 - 0.091 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AFP_2 PF18815.1 KFM76299.1 - 0.17 12.2 0.6 0.91 9.8 0.2 2.3 1 1 1 2 2 2 0 Bacterial antifreeze protein repeat Utp12 PF04003.12 KFM76299.1 - 0.25 11.7 2.9 1.9 8.8 0.0 2.8 3 0 0 3 3 3 0 Dip2/Utp12 Family Tnp_22_trimer PF17489.2 KFM76299.1 - 0.54 10.3 2.8 4.2 7.4 0.0 3.0 4 0 0 4 4 4 0 L1 transposable element trimerization domain MutS_V PF00488.21 KFM76300.1 - 1.4e-46 158.9 0.0 2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 MutS domain V zf-H2C2_2 PF13465.6 KFM76301.1 - 2.5e-60 198.3 53.8 3.3e-08 33.6 0.1 9.1 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76301.1 - 1.9e-45 150.8 54.1 1.8e-06 28.1 1.0 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76301.1 - 9.1e-35 116.3 51.6 0.00016 22.2 0.6 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM76301.1 - 9.3e-23 79.9 49.7 0.0001 22.5 1.1 8.4 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM76301.1 - 6.5e-17 61.1 47.8 0.0012 18.7 0.6 8.9 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM76301.1 - 6e-11 41.9 40.6 0.044 13.5 1.2 8.7 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM76301.1 - 1.2e-10 41.3 42.5 0.036 14.4 0.6 8.7 8 1 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KFM76301.1 - 1e-07 31.9 47.2 0.26 11.4 2.2 8.0 1 1 7 8 8 8 5 BED zinc finger BolA PF01722.18 KFM76301.1 - 1.6e-06 28.3 3.0 2.7 8.3 0.1 5.1 1 1 4 5 5 5 1 BolA-like protein TRAF6_Z2 PF18048.1 KFM76301.1 - 4.8e-06 26.6 31.3 0.16 12.1 0.3 7.6 8 0 0 8 8 8 3 TNF receptor-associated factor 6 zinc finger 2 zf_UBZ PF18439.1 KFM76301.1 - 4.1e-05 23.1 28.8 0.58 9.8 0.0 7.5 8 0 0 8 8 8 4 Ubiquitin-Binding Zinc Finger Baculo_IE-1 PF05290.11 KFM76301.1 - 0.00017 21.6 22.7 3 7.8 0.7 7.0 1 1 5 6 6 6 1 Baculovirus immediate-early protein (IE-0) zf-C2H2_2 PF12756.7 KFM76301.1 - 0.00037 20.8 42.4 0.97 9.8 0.6 7.5 1 1 4 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM76301.1 - 0.00045 20.1 25.3 10 6.1 0.3 8.3 8 0 0 8 8 8 0 zinc-finger of a C2HC-type FYVE PF01363.21 KFM76301.1 - 0.00081 19.5 35.0 2.4 8.4 9.5 5.5 2 1 2 4 4 4 1 FYVE zinc finger XPA_N PF01286.18 KFM76301.1 - 0.0015 18.5 25.6 2.7 8.1 0.3 8.0 8 0 0 8 8 8 1 XPA protein N-terminal C1_1 PF00130.22 KFM76301.1 - 0.0019 18.0 39.5 1.7 8.6 5.0 7.5 2 2 5 7 7 7 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KFM76301.1 - 0.0035 17.4 26.9 1.6 8.9 1.4 5.7 3 2 3 6 6 6 2 Zinc ribbon domain zf-Sec23_Sec24 PF04810.15 KFM76301.1 - 0.0061 16.6 25.0 1.2 9.2 0.1 6.9 4 3 4 8 8 8 1 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM76301.1 - 0.012 15.6 28.7 0.17 11.9 3.0 5.5 5 1 1 6 6 6 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM76301.1 - 0.044 14.5 25.1 1.2 9.9 2.3 4.3 1 1 3 4 4 4 0 zinc-ribbon family Zf_RING PF16744.5 KFM76301.1 - 0.055 13.6 28.4 3.5 7.8 0.2 7.6 2 2 6 8 8 8 0 KIAA1045 RING finger zf-CHCC PF10276.9 KFM76301.1 - 0.1 12.7 17.2 9.1 6.4 0.0 6.7 8 0 0 8 8 7 0 Zinc-finger domain BHD_1 PF10403.9 KFM76301.1 - 0.36 10.7 2.8 23 4.9 0.1 4.0 4 2 1 5 5 4 0 Rad4 beta-hairpin domain 1 zinc-ribbons_6 PF07191.12 KFM76301.1 - 0.43 10.6 26.4 12 5.9 1.1 5.7 1 1 3 4 4 4 0 zinc-ribbons DUF2256 PF10013.9 KFM76301.1 - 0.45 10.7 30.7 2.8 8.1 0.2 7.8 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFM76301.1 - 0.55 9.9 0.1 0.55 9.9 0.1 5.4 5 2 2 7 7 6 0 MYST family zinc finger domain HNH_5 PF14279.6 KFM76301.1 - 2.1 8.3 30.1 1.4 8.8 1.9 7.2 6 2 0 6 6 6 0 HNH endonuclease ZZ PF00569.17 KFM76301.1 - 2.5 8.0 32.7 4.7 7.1 0.3 7.3 8 0 0 8 8 8 0 Zinc finger, ZZ type FYDLN_acid PF09538.10 KFM76301.1 - 4.5 8.0 16.6 69 4.2 0.1 6.2 2 2 5 7 7 6 0 Protein of unknown function (FYDLN_acid) Sprouty PF05210.13 KFM76301.1 - 4.5 7.7 22.9 61 4.1 2.4 3.8 1 1 2 3 3 3 0 Sprouty protein (Spry) zf-C2H2_9 PF16293.5 KFM76301.1 - 7.5 6.5 23.9 28 4.7 0.6 6.9 3 2 5 8 8 8 0 C2H2 type zinc-finger (1 copy) Tma16 PF11176.8 KFM76302.1 - 0.069 13.0 1.4 0.072 13.0 1.4 1.1 1 0 0 1 1 1 0 Translation machinery-associated protein 16 Ldl_recept_a PF00057.18 KFM76303.1 - 2.1e-08 34.2 7.5 2.1e-08 34.2 7.5 2.6 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A CCT_2 PF09425.10 KFM76303.1 - 0.13 12.2 1.0 0.26 11.2 1.0 1.5 1 0 0 1 1 1 0 Divergent CCT motif RIBIOP_C PF04950.12 KFM76304.1 - 2.9e-84 283.0 0.2 2.9e-84 283.0 0.2 1.5 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFM76305.1 - 1.3e-25 89.3 0.0 1.3e-25 89.3 0.0 3.0 3 1 0 3 3 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KFM76305.1 - 1.2e-05 24.9 3.6 7.3e-05 22.4 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM76305.1 - 0.00035 20.6 0.6 0.0028 17.7 0.6 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KFM76305.1 - 0.001 19.5 0.1 0.0024 18.3 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM76305.1 - 0.0038 17.5 0.0 0.0079 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFM76305.1 - 0.0059 16.6 0.0 0.04 14.0 0.0 2.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KFM76305.1 - 0.015 15.0 0.4 0.04 13.7 0.4 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KFM76305.1 - 0.016 15.5 0.1 0.059 13.6 0.1 2.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 KFM76305.1 - 0.021 14.7 0.2 0.074 12.9 0.2 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 KFM76305.1 - 0.032 14.6 0.0 0.16 12.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KFM76305.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KFM76305.1 - 0.091 12.8 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KFM76305.1 - 0.13 12.2 0.6 0.3 11.0 0.6 1.6 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 KFM76305.1 - 0.25 11.9 0.0 0.25 11.9 0.0 2.8 2 1 0 2 2 1 0 ABC transporter Menin PF05053.13 KFM76305.1 - 2.7 6.3 15.1 5 5.4 15.1 1.4 1 0 0 1 1 1 0 Menin Spaetzle PF16077.5 KFM76306.1 - 1.8e-24 86.1 0.7 3.7e-24 85.1 0.7 1.6 1 0 0 1 1 1 1 Spaetzle DUF1325 PF07039.11 KFM76307.1 - 1.4e-32 112.6 0.9 3.5e-32 111.3 0.0 1.9 2 1 0 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KFM76307.1 - 0.0028 17.5 0.6 0.025 14.4 0.1 2.6 3 0 0 3 3 3 1 DNA repair protein Crb2 Tudor domain RPW8 PF05659.11 KFM76307.1 - 0.0062 16.2 1.6 0.0099 15.6 1.6 1.2 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 AbiTii PF18864.1 KFM76307.1 - 0.014 15.6 0.4 0.036 14.2 0.0 1.8 2 1 0 2 2 2 0 AbiTii FHIPEP PF00771.20 KFM76307.1 - 0.21 10.0 1.3 0.25 9.8 1.3 1.1 1 0 0 1 1 1 0 FHIPEP family Fib_alpha PF08702.10 KFM76307.1 - 0.53 10.5 4.9 0.92 9.7 4.9 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.22 KFM76308.1 - 4.5e-31 106.5 0.2 1.9e-17 62.8 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM76308.1 - 4.7e-05 23.0 0.0 0.015 14.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM76308.1 - 7.8e-05 22.7 0.7 0.0014 18.6 0.1 2.4 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFM76308.1 - 0.0011 18.9 0.1 0.0046 16.9 0.1 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 KFM76308.1 - 0.024 14.6 0.1 0.4 10.7 0.1 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_occluded PF16842.5 KFM76308.1 - 0.024 14.5 0.0 0.085 12.7 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_7 PF16367.5 KFM76308.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif OB_RNB PF08206.11 KFM76308.1 - 0.14 11.8 1.0 0.48 10.1 0.4 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain FAM76 PF16046.5 KFM76308.1 - 7.3 5.9 19.3 9.7 5.5 19.3 1.2 1 0 0 1 1 1 0 FAM76 protein BRCT PF00533.26 KFM76310.1 - 2.9e-05 24.4 0.0 3.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFM76310.1 - 0.021 14.7 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 twin BRCT domain Ras PF00071.22 KFM76312.1 - 2.1e-09 37.2 0.0 2.6e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Ras family DUF2757 PF10955.8 KFM76312.1 - 0.022 15.0 0.0 0.026 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) NAD_Gly3P_dh_N PF01210.23 KFM76312.1 - 0.066 13.2 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ras PF00071.22 KFM76313.1 - 1.3e-37 128.9 0.9 1.4e-37 128.8 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM76313.1 - 1.5e-27 96.2 0.4 1.7e-27 96.0 0.4 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM76313.1 - 4.3e-11 42.6 0.1 4.8e-11 42.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFM76313.1 - 5.9e-05 22.6 0.0 7.2e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFM76313.1 - 0.00015 21.9 0.0 0.00017 21.6 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM76313.1 - 0.0011 18.3 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 KFM76313.1 - 0.035 13.8 0.1 0.044 13.5 0.1 1.3 1 1 0 1 1 1 0 AAA domain DUF3873 PF12989.7 KFM76313.1 - 0.089 13.2 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) FeoB_N PF02421.18 KFM76313.1 - 0.13 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B NPCC PF08058.11 KFM76314.1 - 0.13 12.3 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex component Tmemb_55A PF09788.9 KFM76315.1 - 2.9 6.9 4.4 3.3 6.7 3.6 1.4 1 1 0 1 1 1 0 Transmembrane protein 55A Ribosomal_S16 PF00886.19 KFM76316.1 - 1.9e-17 63.0 0.0 2.6e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 WRNPLPNID PF15017.6 KFM76317.1 - 1.2e-12 48.5 4.0 7.4e-06 26.8 0.6 2.1 2 0 0 2 2 2 2 Putative WW-binding domain and destruction box MALT1_Ig PF18703.1 KFM76319.1 - 0.082 12.9 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 MALT1 Ig-like domain DUF2150 PF09920.9 KFM76319.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Zn_ribbon_recom PF13408.6 KFM76320.1 - 0.024 15.2 0.9 0.036 14.6 0.9 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Frizzled PF01534.17 KFM76320.1 - 0.042 12.9 0.9 0.045 12.8 0.9 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Kin17_mid PF10357.9 KFM76321.1 - 7.2e-53 177.8 2.3 7.2e-53 177.8 2.3 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KFM76321.1 - 0.0068 16.8 6.3 0.014 15.8 6.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFM76321.1 - 0.11 12.9 5.4 0.12 12.7 0.7 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFM76321.1 - 0.27 11.6 7.9 0.14 12.5 5.6 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.12 KFM76321.1 - 6 7.1 12.1 0.18 12.0 1.9 2.7 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Glyco_hydro_20 PF00728.22 KFM76323.1 - 7.9e-14 51.8 0.7 1.2e-13 51.2 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF4838 PF16126.5 KFM76323.1 - 5e-10 39.2 0.1 1.2e-09 38.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4838) Hyd_WA PF06462.12 KFM76324.1 - 2.1e-24 85.2 21.0 7.1e-10 38.7 1.3 5.1 5 0 0 5 5 5 4 Propeller Pex24p PF06398.11 KFM76324.1 - 5.4e-10 38.8 4.8 6.9e-10 38.5 4.8 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Hyd_WA PF06462.12 KFM76325.1 - 1.5e-26 92.0 22.0 2.1e-11 43.6 0.4 5.3 5 0 0 5 5 5 4 Propeller Pex24p PF06398.11 KFM76325.1 - 4.3e-12 45.7 5.1 4.3e-12 45.7 5.1 1.5 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin PH PF00169.29 KFM76325.1 - 0.00089 19.7 1.2 0.0035 17.8 1.6 1.8 2 0 0 2 2 2 1 PH domain Perilipin PF03036.16 KFM76326.1 - 8.4e-43 146.9 5.9 2.1e-22 79.7 0.8 2.2 1 1 1 2 2 2 2 Perilipin family DUF883 PF05957.13 KFM76326.1 - 2.5 8.8 6.0 2.2 8.9 0.0 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Serinc PF03348.15 KFM76327.1 - 1.6e-27 96.5 10.1 1.8e-27 96.4 10.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Bac_export_2 PF01312.19 KFM76327.1 - 0.27 10.4 1.9 0.32 10.2 1.9 1.0 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Serinc PF03348.15 KFM76328.1 - 4.9e-51 174.0 7.2 5.4e-51 173.9 7.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF1772 PF08592.11 KFM76328.1 - 0.83 10.0 4.6 2.8 8.3 4.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Cation_ATPase_C PF00689.21 KFM76328.1 - 3.9 7.2 9.5 6.3 6.5 8.4 1.8 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF805 PF05656.14 KFM76328.1 - 7.5 7.0 9.5 29 5.2 9.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Serinc PF03348.15 KFM76329.1 - 7.2e-21 74.6 3.8 8e-21 74.5 3.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ADAM_spacer1 PF05986.14 KFM76330.1 - 1.4e-21 76.7 0.0 3.8e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 ADAM-TS Spacer 1 NTR PF01759.21 KFM76330.1 - 8.1e-16 57.8 0.9 1.9e-15 56.6 0.9 1.6 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TSP_1 PF00090.19 KFM76330.1 - 1.6e-10 41.0 7.6 1.6e-10 41.0 7.6 2.8 2 0 0 2 2 2 1 Thrombospondin type 1 domain TIMP PF00965.17 KFM76330.1 - 9.6e-07 28.8 1.2 2.2e-06 27.6 1.2 1.6 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase zf-H2C2_2 PF13465.6 KFM76331.1 - 1.4e-50 167.5 67.1 4.3e-07 30.1 1.8 9.2 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76331.1 - 6.7e-31 105.0 76.0 1.2e-05 25.5 2.2 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76331.1 - 9.9e-26 88.2 74.6 0.0003 21.4 0.9 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM76331.1 - 3.5e-16 59.0 74.9 0.0017 18.7 1.5 8.5 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM76331.1 - 6.3e-14 51.4 47.3 0.0034 17.1 0.2 8.7 9 0 0 9 9 9 7 C2H2-type zinc-finger domain BolA PF01722.18 KFM76331.1 - 1.2e-11 44.7 10.9 0.052 13.8 0.5 6.4 1 1 5 6 6 6 3 BolA-like protein zf-C2HC_2 PF13913.6 KFM76331.1 - 1.5e-10 40.7 25.2 0.17 11.8 0.1 8.4 8 0 0 8 8 8 4 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFM76331.1 - 5.6e-07 29.4 57.2 1.1 9.4 1.5 9.4 9 0 0 9 9 8 7 C2H2-type zinc finger zf-RRPl_C4 PF17026.5 KFM76331.1 - 0.00034 20.7 35.7 0.068 13.3 6.1 3.4 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type Tox-HNH-HHH PF15637.6 KFM76331.1 - 0.00059 20.0 1.9 6.5 7.0 0.0 3.9 1 1 3 4 4 4 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif GAGA PF09237.11 KFM76331.1 - 0.00079 19.2 28.3 0.41 10.5 0.8 6.5 2 2 5 7 7 7 2 GAGA factor IGPD PF00475.18 KFM76331.1 - 0.001 19.4 5.5 1.2 9.4 0.4 3.4 3 1 0 3 3 3 2 Imidazoleglycerol-phosphate dehydratase PqqA PF08042.11 KFM76331.1 - 0.0028 17.6 2.6 2.9e+02 1.7 0.0 6.3 7 0 0 7 7 7 0 PqqA family zf-CHCC PF10276.9 KFM76331.1 - 0.0039 17.2 7.4 92 3.2 0.0 7.2 8 0 0 8 8 8 0 Zinc-finger domain ADK_lid PF05191.14 KFM76331.1 - 0.0047 16.9 23.4 0.36 10.8 1.8 5.8 1 1 4 5 5 5 1 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KFM76331.1 - 0.0047 16.9 36.1 4.1 7.5 0.1 8.5 6 3 3 9 9 9 2 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KFM76331.1 - 0.005 17.1 52.0 0.44 10.9 0.2 8.4 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 KFM76331.1 - 0.013 15.6 41.2 7.5 6.8 0.1 8.3 8 0 0 8 8 8 0 DBF zinc finger CBP_BcsQ PF06564.12 KFM76331.1 - 0.014 14.9 4.0 1.6 8.2 0.1 2.8 1 1 1 3 3 3 0 Cellulose biosynthesis protein BcsQ zf-MYST PF17772.1 KFM76331.1 - 0.026 14.1 44.4 0.2 11.3 0.4 8.0 2 2 6 8 8 8 0 MYST family zinc finger domain TRAF6_Z2 PF18048.1 KFM76331.1 - 0.1 12.7 49.3 0.35 11.0 0.1 7.8 8 0 0 8 8 8 0 TNF receptor-associated factor 6 zinc finger 2 BHD_1 PF10403.9 KFM76331.1 - 0.13 12.1 6.9 11 5.9 0.0 4.9 5 3 0 5 5 5 0 Rad4 beta-hairpin domain 1 DUF4990 PF16380.5 KFM76331.1 - 0.33 11.1 3.7 26 4.9 0.0 4.0 6 0 0 6 6 5 0 Domain of unknown function RecR PF02132.15 KFM76331.1 - 3.9 7.1 36.8 11 5.7 3.5 7.7 6 2 0 6 6 6 0 RecR protein DUF5330 PF17264.2 KFM76331.1 - 6 7.0 17.9 1e+02 3.0 0.1 6.7 8 0 0 8 8 7 0 Family of unknown function (DUF5330) E1_DerP2_DerF2 PF02221.15 KFM76332.1 - 4.1e-09 37.0 0.2 5.2e-09 36.6 0.2 1.1 1 0 0 1 1 1 1 ML domain Atg14 PF10186.9 KFM76333.1 - 8e-20 71.2 0.1 1e-19 70.8 0.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 WD40 PF00400.32 KFM76334.1 - 1e-22 79.9 14.8 0.001 19.8 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ATG16 PF08614.11 KFM76334.1 - 9.2e-18 65.2 13.0 9.2e-18 65.2 13.0 1.4 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) ANAPC4_WD40 PF12894.7 KFM76334.1 - 2e-06 28.0 1.5 0.92 9.8 0.0 4.9 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM76334.1 - 0.0017 17.8 1.4 0.37 10.1 0.1 3.0 2 1 0 3 3 3 1 WD40-like domain HPS3_N PF14761.6 KFM76334.1 - 0.0023 17.5 2.4 0.087 12.3 0.7 2.8 3 1 0 3 3 3 1 Hermansky-Pudlak syndrome 3 Taxilin PF09728.9 KFM76334.1 - 0.0034 16.6 15.9 0.0053 16.0 14.8 1.8 1 1 0 1 1 1 1 Myosin-like coiled-coil protein HALZ PF02183.18 KFM76334.1 - 0.0039 17.4 2.2 0.013 15.7 2.2 1.9 1 0 0 1 1 1 1 Homeobox associated leucine zipper Pih1_fungal_CS PF18482.1 KFM76334.1 - 0.034 14.7 1.6 0.14 12.7 0.9 2.3 2 0 0 2 2 2 0 Fungal Pih1 CS domain CortBP2 PF09727.9 KFM76334.1 - 0.04 13.8 12.6 0.072 13.0 12.6 1.4 1 0 0 1 1 1 0 Cortactin-binding protein-2 YfhE PF14152.6 KFM76334.1 - 0.061 13.4 0.2 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 YfhE-like protein GAS PF13851.6 KFM76334.1 - 0.095 12.0 18.5 1.4 8.3 13.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF613 PF04764.12 KFM76334.1 - 0.1 12.7 3.2 0.26 11.4 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF613) Spc29 PF17082.5 KFM76334.1 - 0.2 11.4 7.0 0.43 10.4 7.0 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 Fez1 PF06818.15 KFM76334.1 - 0.24 11.8 11.2 0.54 10.7 11.2 1.6 1 0 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 KFM76334.1 - 0.29 11.2 13.4 0.17 11.9 5.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 KFM76334.1 - 0.31 10.6 8.7 0.58 9.7 8.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit KASH_CCD PF14662.6 KFM76334.1 - 0.4 10.5 21.9 0.14 12.0 8.5 2.7 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TMPIT PF07851.13 KFM76334.1 - 2.7 7.2 14.2 1.6 7.9 6.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein ZapB PF06005.12 KFM76334.1 - 3.2 8.3 9.1 4.2 7.9 1.4 2.9 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 KFM76334.1 - 4 8.1 12.0 0.43 11.2 1.6 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 KFM76334.1 - 7.5 6.6 9.2 2.2 8.3 1.6 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AATF-Che1 PF13339.6 KFM76334.1 - 9.2 7.0 18.1 7.2e+02 0.8 16.2 3.9 3 1 0 3 3 2 0 Apoptosis antagonizing transcription factor AAA PF00004.29 KFM76336.1 - 2.9e-20 73.0 0.0 8.2e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KFM76336.1 - 1.1e-15 58.1 0.0 1.8e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal RNA_helicase PF00910.22 KFM76336.1 - 0.00015 22.1 0.0 0.00043 20.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_16 PF13191.6 KFM76336.1 - 0.00059 20.3 0.1 0.0048 17.3 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KFM76336.1 - 0.00072 18.8 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Rad17 PF03215.15 KFM76336.1 - 0.00094 19.1 0.0 0.01 15.8 0.0 2.1 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KFM76336.1 - 0.0017 18.4 0.0 0.0039 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KFM76336.1 - 0.0059 17.1 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KFM76336.1 - 0.011 15.4 0.0 0.026 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFM76336.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFM76336.1 - 0.018 15.6 0.0 0.038 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFM76336.1 - 0.035 13.8 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM76336.1 - 0.035 14.2 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM76336.1 - 0.043 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KFM76336.1 - 0.056 12.8 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 KaiC RuvB_N PF05496.12 KFM76336.1 - 0.064 13.0 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KFM76336.1 - 0.081 13.2 0.0 0.28 11.4 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KFM76336.1 - 0.084 13.1 0.0 0.62 10.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KFM76336.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFM76336.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Abhydrolase_1 PF00561.20 KFM76337.1 - 3.4e-20 72.8 0.0 1.1e-19 71.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM76337.1 - 1.1e-17 65.3 0.0 1.5e-17 65.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM76337.1 - 1.7e-12 47.1 0.0 3.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KFM76337.1 - 2.9e-06 27.1 0.0 1.9e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KFM76337.1 - 1.9e-05 24.5 0.0 0.0024 17.6 0.0 2.1 1 1 1 2 2 2 2 PGAP1-like protein DUF915 PF06028.11 KFM76337.1 - 0.0028 17.0 0.0 0.034 13.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 KFM76337.1 - 0.012 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ndr PF03096.14 KFM76337.1 - 0.058 12.1 0.0 0.23 10.1 0.0 1.7 2 0 0 2 2 2 0 Ndr family Abhydro_lipase PF04083.16 KFM76337.1 - 0.076 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Lipase_3 PF01764.25 KFM76337.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KFM76337.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Urb2 PF10441.9 KFM76338.1 - 8e-21 74.9 1.4 8e-21 74.9 1.4 3.0 3 1 0 3 3 3 1 Urb2/Npa2 family RNA_binding PF01877.17 KFM76338.1 - 0.3 11.4 3.5 0.36 11.1 0.2 2.8 3 0 0 3 3 3 0 RNA binding Lactamase_B_2 PF12706.7 KFM76342.1 - 7.9e-16 58.2 0.0 1.6e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KFM76342.1 - 7.1e-09 35.2 0.0 4.1e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 KFM76342.1 - 0.00019 21.5 0.0 0.00046 20.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Sulfate_transp PF00916.20 KFM76343.1 - 4.9e-51 173.7 9.3 6e-51 173.4 9.3 1.0 1 0 0 1 1 1 1 Sulfate permease family DUF5493 PF17597.2 KFM76343.1 - 0.067 13.5 2.1 0.14 12.5 0.5 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5493) SPG48 PF14764.6 KFM76343.1 - 0.092 13.2 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking Sulfate_transp PF00916.20 KFM76344.1 - 5e-07 28.8 1.3 5.1e-07 28.8 1.3 1.0 1 0 0 1 1 1 1 Sulfate permease family Cystatin PF00031.21 KFM76345.1 - 0.072 13.4 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Cystatin domain BTB PF00651.31 KFM76347.1 - 8.6e-25 87.1 0.5 1.3e-24 86.5 0.5 1.3 1 0 0 1 1 1 1 BTB/POZ domain EMG1 PF03587.14 KFM76348.1 - 2.1e-83 278.7 0.1 2.6e-83 278.5 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF5329 PF17263.2 KFM76348.1 - 0.16 12.2 0.6 0.31 11.3 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5329) zf-MYND PF01753.18 KFM76349.1 - 1.1e-07 31.8 11.6 3.4e-07 30.2 11.6 1.9 1 0 0 1 1 1 1 MYND finger DUF2746 PF10874.8 KFM76349.1 - 0.053 14.0 0.1 0.18 12.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) MbeB_N PF04837.12 KFM76349.1 - 6.9 7.1 11.9 0.54 10.6 0.7 3.9 4 0 0 4 4 4 0 MbeB-like, N-term conserved region CBFD_NFYB_HMF PF00808.23 KFM76350.1 - 3.8e-10 39.9 0.2 6.1e-10 39.3 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Coilin_N PF15862.5 KFM76350.1 - 0.065 13.0 0.2 0.094 12.5 0.2 1.2 1 0 0 1 1 1 0 Coilin N-terminus Histone PF00125.24 KFM76350.1 - 2.9 8.3 6.5 1.9 8.9 0.5 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 fn3 PF00041.21 KFM76351.1 - 2.2e-89 293.9 25.3 1.5e-17 63.7 0.1 6.8 7 0 0 7 7 6 6 Fibronectin type III domain I-set PF07679.16 KFM76351.1 - 2.8e-41 139.5 0.0 3.4e-16 59.1 0.0 4.3 5 0 0 5 5 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM76351.1 - 1.3e-40 137.9 0.5 1e-16 61.3 0.0 5.1 5 0 0 5 5 4 3 Immunoglobulin domain Neogenin_C PF06583.12 KFM76351.1 - 5.8e-30 105.1 26.9 1.5e-23 84.1 15.4 2.6 1 1 0 2 2 2 2 Neogenin C-terminus ig PF00047.25 KFM76351.1 - 6.9e-27 93.5 0.1 6.1e-14 52.0 0.0 3.9 4 0 0 4 4 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM76351.1 - 1.7e-25 89.1 0.3 1.4e-11 44.6 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM76351.1 - 1.6e-19 70.3 20.7 0.00015 22.2 0.1 7.3 6 1 0 6 6 6 5 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFM76351.1 - 7.6e-17 61.5 2.0 0.00011 22.3 0.0 6.7 4 2 1 5 5 5 2 Immunoglobulin V-set domain Interfer-bind PF09294.10 KFM76351.1 - 2e-12 47.4 0.2 0.94 9.8 0.1 6.7 6 0 0 6 6 6 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFM76351.1 - 9.8e-09 35.5 0.1 0.29 11.5 0.0 5.7 5 0 0 5 5 5 1 Uncharacterised conserved protein (DUF2369) C2-set_2 PF08205.12 KFM76351.1 - 4.8e-08 33.0 0.0 0.0002 21.3 0.0 3.1 3 0 0 3 3 2 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM76351.1 - 9.2e-06 25.8 0.0 0.047 13.9 0.0 3.5 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFM76351.1 - 0.00048 19.6 0.0 7.8 6.2 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain PhoD_N PF16655.5 KFM76351.1 - 0.0052 17.3 0.6 0.49 11.0 0.1 3.4 4 0 0 4 4 2 1 PhoD-like phosphatase, N-terminal domain Glyco_hydro_36C PF16874.5 KFM76351.1 - 0.015 15.8 0.1 0.88 10.1 0.0 3.5 4 0 0 4 4 2 0 Glycosyl hydrolase family 36 C-terminal domain Adeno_E3_CR2 PF02439.15 KFM76351.1 - 0.021 14.6 8.3 0.045 13.5 8.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ig_C17orf99 PF17736.1 KFM76351.1 - 0.06 13.4 0.0 8.9 6.4 0.0 3.6 3 0 0 3 3 3 0 C17orf99 Ig domain Izumo-Ig PF16706.5 KFM76351.1 - 0.066 13.3 0.0 11 6.2 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain EphA2_TM PF14575.6 KFM76351.1 - 0.1 13.5 0.0 0.22 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Reeler PF02014.16 KFM76351.1 - 0.35 11.6 4.1 28 5.5 0.0 4.3 4 1 1 5 5 3 0 Reeler domain DUF3827 PF12877.7 KFM76351.1 - 8.5 4.6 8.4 0.1 10.9 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) HTH_Tnp_Tc3_2 PF01498.18 KFM76352.1 - 2.3e-16 59.8 2.2 4.2e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76352.1 - 8.9e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Neur_chan_LBD PF02931.23 KFM76353.1 - 6.5e-12 45.4 0.0 8.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM76354.1 - 0.0023 18.1 0.0 0.0023 18.1 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM76355.1 - 2.7e-21 76.0 0.0 2.9e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain UvrD_C PF13361.6 KFM76359.1 - 2.7e-12 46.8 0.0 3.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KFM76359.1 - 1.3e-08 34.6 0.1 3.8e-08 33.0 0.1 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KFM76359.1 - 0.00089 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KFM76360.1 - 2.4e-12 47.0 0.0 4.1e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KFM76360.1 - 6.1e-07 29.9 0.2 9.1e-07 29.3 0.2 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KFM76360.1 - 0.00048 19.9 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KFM76360.1 - 0.021 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFM76360.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 KFM76360.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 KFM76361.1 - 1.5e-07 31.2 0.0 3.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM76361.1 - 8.6e-07 28.7 0.1 2.3e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain AAA_19 PF13245.6 KFM76361.1 - 0.0035 17.7 0.0 0.0059 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM76361.1 - 0.0035 17.1 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KFM76361.1 - 0.026 14.1 0.4 0.059 12.9 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KFM76361.1 - 0.048 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain HTH_Tnp_Tc3_2 PF01498.18 KFM76362.1 - 2.3e-16 59.8 2.2 4.5e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76362.1 - 9.7e-14 51.4 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SCA7 PF08313.12 KFM76363.1 - 0.013 15.4 0.2 0.013 15.4 0.2 1.1 1 0 0 1 1 1 0 SCA7, zinc-binding domain Ferritin PF00210.24 KFM76364.1 - 0.077 12.9 1.0 0.17 11.8 1.0 1.5 1 0 0 1 1 1 0 Ferritin-like domain STIL_N PF15253.6 KFM76365.1 - 1.9e-06 27.1 0.0 1.9e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus STIL_N PF15253.6 KFM76366.1 - 0.041 12.9 0.1 0.042 12.8 0.1 1.0 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus STIL_N PF15253.6 KFM76367.1 - 0.0024 16.9 0.0 0.0026 16.8 0.0 1.0 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus DDE_3 PF13358.6 KFM76369.1 - 3.4e-16 59.3 0.1 6e-15 55.3 0.0 2.6 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76369.1 - 7.8e-16 58.1 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76369.1 - 0.00096 19.7 1.5 0.00096 19.7 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.6 KFM76370.1 - 1.6e-15 57.2 0.0 3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76370.1 - 1.3e-10 41.3 1.0 2.7e-10 40.3 1.0 1.6 1 0 0 1 1 1 1 Transposase DUF5641 PF18701.1 KFM76371.1 - 6.2e-11 42.3 0.1 6.6e-11 42.2 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5641) 7tm_1 PF00001.21 KFM76372.1 - 3.3e-44 151.2 18.3 4.3e-44 150.8 18.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM76372.1 - 0.00017 21.3 19.6 0.00038 20.2 19.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFM76372.1 - 0.00049 19.5 15.7 0.00088 18.7 15.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 KFM76372.1 - 0.0089 15.8 10.3 0.023 14.5 10.3 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 ACAS_N PF16177.5 KFM76373.1 - 0.04 13.8 2.9 0.058 13.3 0.3 2.0 1 1 1 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus zf-H2C2_2 PF13465.6 KFM76374.1 - 5.3e-41 137.3 76.8 3e-07 30.5 0.3 10.8 11 0 0 11 11 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76374.1 - 8e-41 136.3 86.6 8.4e-05 22.8 1.0 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76374.1 - 1.2e-36 122.2 80.9 0.00063 20.4 0.6 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM76374.1 - 1.9e-16 59.6 74.9 0.00045 20.2 0.1 10.5 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM76374.1 - 9.6e-14 51.2 66.7 0.0035 17.6 0.6 10.5 10 0 0 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM76374.1 - 4e-12 46.1 72.3 0.0027 18.0 0.6 10.5 10 0 0 10 10 10 9 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KFM76374.1 - 1.1e-07 31.5 32.0 0.027 14.4 0.1 8.2 9 0 0 9 9 8 3 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM76374.1 - 1e-06 28.3 52.7 0.074 12.7 1.1 9.1 2 2 6 9 9 9 5 MYST family zinc finger domain BolA PF01722.18 KFM76374.1 - 1.3e-06 28.6 17.2 4.9 7.5 0.0 6.7 2 2 5 7 7 7 3 BolA-like protein zf-Di19 PF05605.12 KFM76374.1 - 0.011 16.0 54.1 0.76 10.1 0.4 7.3 2 2 6 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding Ta0938 PF11494.8 KFM76374.1 - 0.3 11.4 28.1 0.19 12.0 1.8 7.0 1 1 6 7 7 7 0 Ta0938 FYDLN_acid PF09538.10 KFM76374.1 - 2.9 8.6 16.9 1.9 9.2 0.2 6.0 3 2 2 6 6 6 0 Protein of unknown function (FYDLN_acid) LIM PF00412.22 KFM76374.1 - 4.1 7.7 50.1 0.42 10.9 5.2 7.3 2 2 6 8 8 8 0 LIM domain THAP PF05485.12 KFM76375.1 - 2.8e-05 24.9 2.0 3.1e-05 24.8 2.0 1.0 1 0 0 1 1 1 1 THAP domain zf-H2C2_2 PF13465.6 KFM76376.1 - 4.1e-61 200.8 90.6 1.8e-07 31.3 0.6 14.4 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76376.1 - 1.3e-45 151.4 105.4 6.9e-05 23.1 1.4 13.7 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76376.1 - 4e-42 139.2 102.4 0.001 19.7 1.1 13.7 14 0 0 14 14 14 13 C2H2-type zinc finger zf-met PF12874.7 KFM76376.1 - 5.2e-25 87.0 88.0 0.00014 22.1 0.9 13.6 14 0 0 14 14 14 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM76376.1 - 7e-19 67.6 84.9 0.00026 21.2 0.3 13.6 13 1 1 14 14 14 11 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM76376.1 - 3e-16 59.0 81.7 8.9e-05 22.4 0.6 12.6 12 0 0 12 12 12 10 C2H2-type zinc finger BolA PF01722.18 KFM76376.1 - 0.00017 21.8 15.2 15 5.9 0.0 7.9 2 2 6 8 8 8 1 BolA-like protein Mga PF05043.13 KFM76376.1 - 0.32 11.6 2.4 32 5.2 0.0 2.9 2 1 0 3 3 3 0 Mga helix-turn-helix domain zf-C2HC_2 PF13913.6 KFM76376.1 - 0.4 10.6 0.1 0.4 10.6 0.1 10.1 12 0 0 12 12 12 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM76376.1 - 2.7 7.7 51.6 0.79 9.4 1.5 10.6 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger HTH_Tnp_Tc3_2 PF01498.18 KFM76377.1 - 1.9e-17 63.3 2.2 6.7e-16 58.3 2.2 2.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76377.1 - 1.5e-13 50.7 0.0 2.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76377.1 - 2.8e-07 30.2 1.6 8.1e-07 28.7 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76377.1 - 0.0023 17.7 0.5 0.0087 15.8 0.5 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76377.1 - 2.6 8.7 15.6 0.14 12.8 2.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain PP2C PF00481.21 KFM76379.1 - 4.6e-58 196.9 0.0 5.8e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFM76379.1 - 1.9e-05 24.4 0.0 4.4e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C COMPASS-Shg1 PF05205.12 KFM76379.1 - 0.0029 18.3 0.1 0.0063 17.2 0.1 1.5 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Pkinase PF00069.25 KFM76380.1 - 4.3e-77 259.1 0.0 6e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM76380.1 - 1.2e-49 169.0 0.0 1.7e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM76380.1 - 5.3e-07 28.8 0.1 1.1e-06 27.7 0.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM76380.1 - 4.3e-05 23.0 0.1 0.0025 17.2 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KFM76380.1 - 0.0039 17.2 0.0 2 8.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFM76380.1 - 0.034 13.5 0.0 0.099 12.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFM76380.1 - 0.078 11.9 3.1 0.23 10.4 3.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain DSHCT PF08148.12 KFM76380.1 - 0.098 12.3 0.1 0.17 11.5 0.1 1.5 1 1 0 1 1 1 0 DSHCT (NUC185) domain PBD PF00786.28 KFM76381.1 - 1.2e-23 83.2 0.0 2.5e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain HAGH_C PF16123.5 KFM76382.1 - 5.7e-25 87.6 0.1 1.3e-24 86.5 0.1 1.6 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KFM76382.1 - 9.2e-14 51.9 0.9 1.3e-05 25.3 0.8 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFM76382.1 - 0.00023 20.8 0.8 0.00056 19.5 0.8 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFM76382.1 - 0.083 12.8 0.6 0.19 11.6 0.6 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain AP-5_subunit_s1 PF15001.6 KFM76383.1 - 1.5e-23 83.8 0.8 2.4e-21 76.7 0.8 2.1 1 1 0 1 1 1 1 AP-5 complex subunit sigma-1 DDE_Tnp_1_7 PF13843.6 KFM76384.1 - 4e-35 121.7 0.4 6.3e-35 121.1 0.1 1.5 2 0 0 2 2 2 1 Transposase IS4 RhoGEF PF00621.20 KFM76384.1 - 2.9e-15 57.0 0.1 5.4e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain ECH_2 PF16113.5 KFM76385.1 - 7.1e-137 456.4 0.0 8.2e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KFM76385.1 - 6e-31 107.7 0.0 2.1e-27 96.1 0.0 2.1 1 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Acetate_kinase PF00871.17 KFM76385.1 - 0.15 10.7 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Acetokinase family BRO1 PF03097.18 KFM76386.1 - 1.9e-112 375.9 4.1 3.1e-112 375.2 4.1 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KFM76386.1 - 2.1e-89 299.8 5.6 2.1e-89 299.8 5.6 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV SUIM_assoc PF16619.5 KFM76386.1 - 0.015 15.4 1.0 0.015 15.4 1.0 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NifQ PF04891.12 KFM76386.1 - 0.022 15.1 0.2 0.11 12.9 0.2 2.2 1 0 0 1 1 1 0 NifQ PSD4 PF07631.11 KFM76386.1 - 0.036 14.6 0.9 0.089 13.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) PTPlike_phytase PF14566.6 KFM76386.1 - 0.046 13.8 0.4 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate CLZ PF16526.5 KFM76386.1 - 2.3 8.6 12.3 2.7 8.4 0.4 4.3 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2203 PF09969.9 KFM76386.1 - 4.2 8.1 6.6 3.7 8.3 0.1 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) HTH_48 PF17906.1 KFM76387.1 - 6.1e-06 26.2 0.1 1.3e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM76387.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KFM76387.1 - 0.014 15.5 0.1 0.022 14.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KFM76387.1 - 0.11 12.8 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Transposase DDE_3 PF13358.6 KFM76388.1 - 4.8e-07 29.6 0.4 2.5e-06 27.3 0.4 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease Glucos_trans_II PF14264.6 KFM76389.1 - 0.61 9.4 19.6 0.65 9.3 19.6 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII VraX PF17412.2 KFM76390.1 - 0.32 10.7 1.9 1.7 8.3 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function NADH5_C PF06455.11 KFM76392.1 - 0.73 9.4 2.2 16 5.0 0.3 2.5 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus THAP PF05485.12 KFM76393.1 - 3e-10 40.9 0.4 3.8e-10 40.6 0.4 1.1 1 0 0 1 1 1 1 THAP domain AA_permease_2 PF13520.6 KFM76396.1 - 9.8e-49 166.3 28.5 1.2e-48 166.0 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM76396.1 - 1.5e-18 66.7 28.5 1.9e-18 66.3 28.5 1.2 1 0 0 1 1 1 1 Amino acid permease RNase_T PF00929.24 KFM76397.1 - 5e-05 23.9 1.5 7.4e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 Exonuclease IMS PF00817.20 KFM76399.1 - 1.7e-46 158.0 0.7 4.2e-46 156.6 0.7 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFM76399.1 - 2.8e-22 79.6 0.1 6e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFM76399.1 - 5.8e-06 26.3 0.0 1.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif CYTL1 PF15153.6 KFM76399.1 - 0.048 13.6 1.0 0.18 11.8 0.2 2.3 2 0 0 2 2 2 0 Cytokine-like protein 1 RNF220 PF15926.5 KFM76399.1 - 0.072 12.7 3.3 0.56 9.8 0.1 2.4 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 NPV_P10 PF05531.12 KFM76399.1 - 0.39 11.2 2.3 3.8 8.0 0.6 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 KFM76399.1 - 3.1 8.1 5.4 3.6 7.9 3.0 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Mlf1IP PF10248.9 KFM76400.1 - 9.9e-62 207.9 10.5 9.9e-62 207.9 10.5 1.9 2 0 0 2 2 2 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Glyco_hydro_38N PF01074.22 KFM76400.1 - 0.0032 16.9 0.3 0.15 11.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Endonuclea_NS_2 PF13930.6 KFM76400.1 - 0.011 15.8 3.2 0.031 14.4 3.2 1.7 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease SOG2 PF10428.9 KFM76400.1 - 0.96 8.6 12.6 1.1 8.4 12.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Myosin_tail_1 PF01576.19 KFM76401.1 - 0 1332.5 326.1 0 1332.2 326.1 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 KFM76401.1 - 0 1028.0 0.2 0 1028.0 0.2 2.8 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.19 KFM76401.1 - 2.3e-12 46.6 1.8 6e-12 45.2 1.8 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFM76401.1 - 0.077 13.3 0.0 0.077 13.3 0.0 6.7 6 3 2 8 8 8 0 AAA domain IQ PF00612.27 KFM76401.1 - 0.19 11.6 3.6 0.089 12.6 0.4 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_7 PF12775.7 KFM76401.1 - 0.23 10.9 2.5 1.9 8.0 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region fn3 PF00041.21 KFM76402.1 - 0.06 13.7 0.0 0.091 13.1 0.0 1.2 1 0 0 1 1 1 0 Fibronectin type III domain Collectrin PF16959.5 KFM76402.1 - 0.086 12.6 2.1 0.12 12.2 2.1 1.3 1 0 0 1 1 1 0 Renal amino acid transporter Stevor PF17410.2 KFM76402.1 - 0.17 11.4 0.8 0.2 11.2 0.8 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ATP1G1_PLM_MAT8 PF02038.16 KFM76402.1 - 0.28 10.6 1.4 0.56 9.7 1.4 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family TMEM154 PF15102.6 KFM76402.1 - 0.32 10.9 4.1 0.53 10.2 4.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4006 PF13179.6 KFM76402.1 - 0.42 10.6 6.3 0.83 9.6 6.3 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF4006) Podoplanin PF05808.11 KFM76402.1 - 0.73 9.9 4.2 1.1 9.4 4.2 1.2 1 0 0 1 1 1 0 Podoplanin LRR19-TM PF15176.6 KFM76402.1 - 1.1 9.2 2.9 1.8 8.6 2.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain HTH_Tnp_Tc3_2 PF01498.18 KFM76404.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76404.1 - 1e-13 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76405.1 - 1.5e-17 63.6 1.1 2.4e-17 62.9 1.1 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76405.1 - 1.2e-06 29.0 6.3 1.6e-06 28.6 2.3 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM76405.1 - 7.7e-05 22.5 0.8 0.1 12.5 0.0 2.7 3 1 0 3 3 3 2 MarR family PAX PF00292.18 KFM76405.1 - 0.0017 18.3 0.0 0.0029 17.5 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_Crp_2 PF13545.6 KFM76405.1 - 0.0026 17.7 1.4 0.022 14.7 0.1 2.3 1 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_3 PF01381.22 KFM76405.1 - 0.012 15.6 0.5 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_24 PF13412.6 KFM76405.1 - 0.013 15.0 1.6 0.6 9.7 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM76405.1 - 0.015 15.0 3.1 0.25 11.2 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain TrmB PF01978.19 KFM76405.1 - 0.058 13.3 0.1 2.2 8.2 0.0 2.3 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_26 PF13443.6 KFM76405.1 - 0.13 12.7 0.1 4.1 7.9 0.1 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_28 PF13518.6 KFM76405.1 - 0.15 12.2 2.5 5.1 7.3 0.1 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain FUR PF01475.19 KFM76405.1 - 0.17 12.0 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family MULE PF10551.9 KFM76407.1 - 4.8e-08 33.3 0.0 1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_3 PF13358.6 KFM76408.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease dUTPase PF00692.19 KFM76409.1 - 1.7e-10 40.7 0.0 2e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 dUTPase PSP PF04046.16 KFM76410.1 - 4.5e-17 61.7 0.5 8.5e-17 60.8 0.5 1.5 1 0 0 1 1 1 1 PSP Chordopox_A20R PF05941.13 KFM76413.1 - 0.024 13.6 0.0 0.029 13.4 0.0 1.0 1 0 0 1 1 1 0 Chordopoxvirus A20R protein WD40 PF00400.32 KFM76415.1 - 2.4e-61 202.2 27.3 7e-10 39.4 0.5 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM76415.1 - 3.6e-16 59.2 4.9 0.0014 18.9 0.0 5.6 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM76415.1 - 1.7e-09 36.9 13.0 0.0031 16.2 0.0 6.3 4 2 4 8 8 8 5 Nucleoporin Nup120/160 eIF2A PF08662.11 KFM76415.1 - 4.1e-07 30.1 2.0 0.00045 20.2 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KFM76415.1 - 5.8e-07 29.2 0.3 1.3e-06 28.2 0.3 1.6 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 KFM76415.1 - 2.2e-06 26.7 1.0 0.013 14.3 0.0 3.9 1 1 0 2 2 2 2 Nup133 N terminal like Ge1_WD40 PF16529.5 KFM76415.1 - 0.0001 21.4 6.3 1 8.2 0.7 4.6 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ras PF00071.22 KFM76416.1 - 7.1e-36 123.3 0.0 1e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM76416.1 - 1.3e-18 67.4 0.0 2.1e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SOCS_box PF07525.16 KFM76416.1 - 7e-07 29.5 1.3 7e-07 29.5 1.3 2.5 2 0 0 2 2 2 1 SOCS box Arf PF00025.21 KFM76416.1 - 0.00022 20.7 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family WD40 PF00400.32 KFM76417.1 - 1.7e-42 142.6 16.1 1.7e-08 35.0 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM76417.1 - 3.5e-05 24.0 0.9 4.3 7.7 0.1 4.8 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFM76417.1 - 0.034 12.9 0.0 6.7 5.3 0.0 2.9 1 1 1 2 2 2 0 Nup133 N terminal like CH PF00307.31 KFM76420.1 - 5.5e-13 49.1 0.0 5.5e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM76420.1 - 4.7e-09 36.0 0.0 5.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 CAMSAP CH domain Zn_ribbon_recom PF13408.6 KFM76423.1 - 0.024 15.2 0.9 0.036 14.6 0.9 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Frizzled PF01534.17 KFM76423.1 - 0.042 12.9 0.9 0.045 12.8 0.9 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region BTD PF09270.10 KFM76425.1 - 4.4e-76 254.3 0.0 7.4e-76 253.6 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 KFM76425.1 - 3.3e-51 173.9 0.1 6.3e-51 173.0 0.1 1.5 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.24 KFM76425.1 - 0.00029 20.8 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain RHD_dimer PF16179.5 KFM76425.1 - 0.086 12.9 0.0 0.28 11.2 0.0 2.0 1 1 0 1 1 1 0 Rel homology dimerisation domain RhoGAP PF00620.27 KFM76428.1 - 2.3e-39 134.7 0.0 3.3e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain C2 PF00168.30 KFM76428.1 - 0.00048 20.4 0.0 0.00082 19.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain ProSAAS PF07259.12 KFM76428.1 - 0.1 12.6 1.0 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 ProSAAS precursor Rrp40_N PF18311.1 KFM76429.1 - 0.00083 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Pep_M12B_propep PF01562.19 KFM76430.1 - 3.5e-16 59.7 2.1 1.5e-14 54.4 2.1 2.0 1 1 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 KFM76431.1 - 1.7e-18 66.9 2.9 1.7e-18 66.9 2.9 2.7 2 1 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin PF01421.19 KFM76431.1 - 3.9e-15 56.3 0.2 7.2e-15 55.4 0.2 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 KFM76431.1 - 5.1e-10 39.6 0.7 1e-09 38.6 0.7 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM76431.1 - 1e-08 35.6 2.4 2.7e-08 34.2 2.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFM76431.1 - 4e-06 27.4 0.1 7.1e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFM76431.1 - 6.9e-06 25.8 0.1 1e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFM76431.1 - 0.00034 20.5 0.2 0.00056 19.8 0.2 1.3 1 0 0 1 1 1 1 Matrixin TSP_1 PF00090.19 KFM76431.1 - 0.005 17.0 7.7 0.005 17.0 7.7 4.1 4 1 0 4 4 4 1 Thrombospondin type 1 domain Peptidase_M57 PF12388.8 KFM76431.1 - 0.053 13.1 0.3 0.084 12.5 0.3 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Astacin PF01400.24 KFM76431.1 - 0.06 13.0 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF4953 PF16313.5 KFM76431.1 - 0.8 8.9 2.2 1.2 8.3 2.2 1.1 1 0 0 1 1 1 0 Met-zincin TSP_1 PF00090.19 KFM76433.1 - 8.4e-06 25.9 17.6 4.1e-05 23.7 3.7 2.6 2 1 0 2 2 2 2 Thrombospondin type 1 domain DDE_3 PF13358.6 KFM76434.1 - 0.0017 18.2 0.1 0.0017 18.1 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Leu_zip PF15294.6 KFM76435.1 - 0.00084 18.9 9.3 0.00084 18.9 9.3 3.5 1 1 2 4 4 4 2 Leucine zipper DUF724 PF05266.14 KFM76435.1 - 0.26 11.1 45.2 0.12 12.2 7.4 4.1 2 2 1 4 4 4 0 Protein of unknown function (DUF724) ADIP PF11559.8 KFM76435.1 - 4.2 7.4 40.7 0.094 12.8 8.4 3.9 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Lip_prot_lig_C PF10437.9 KFM76435.1 - 4.2 7.4 8.8 13 5.9 0.0 3.9 3 1 1 4 4 4 0 Bacterial lipoate protein ligase C-terminus HAP1_N PF04849.13 KFM76436.1 - 0.00061 19.1 2.2 0.00069 18.9 2.2 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region GAS PF13851.6 KFM76436.1 - 0.00074 18.9 2.5 0.00077 18.9 2.5 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Tektin PF03148.14 KFM76436.1 - 0.0019 17.0 2.2 0.002 16.9 2.2 1.0 1 0 0 1 1 1 1 Tektin family Phage_GP20 PF06810.11 KFM76436.1 - 0.0071 16.2 2.6 0.0078 16.0 2.6 1.1 1 0 0 1 1 1 1 Phage minor structural protein GP20 Angiomotin_C PF12240.8 KFM76436.1 - 0.0075 15.8 1.6 0.0082 15.7 1.6 1.1 1 0 0 1 1 1 1 Angiomotin C terminal 2Fe-2S_thioredx PF01257.19 KFM76436.1 - 0.013 15.4 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Csm1_N PF18504.1 KFM76436.1 - 0.028 14.7 2.6 0.04 14.3 2.6 1.2 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF1877 PF08974.10 KFM76436.1 - 0.041 14.0 0.5 0.055 13.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) CCDC92 PF14916.6 KFM76436.1 - 0.057 13.2 3.9 1.7 8.5 0.9 2.3 1 1 1 2 2 2 0 Coiled-coil domain of unknown function TMF_DNA_bd PF12329.8 KFM76436.1 - 0.085 12.9 7.0 0.12 12.3 7.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Proteasome PF00227.26 KFM76437.1 - 9.9e-61 204.5 0.0 1.5e-60 203.9 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM76437.1 - 1.1e-09 37.7 0.0 1.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-C3HC4_2 PF13923.6 KFM76438.1 - 1.2e-07 31.5 10.6 1.2e-07 31.5 10.6 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM76438.1 - 2.2e-07 31.1 10.4 2.2e-07 31.1 10.4 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM76438.1 - 2.6e-07 30.4 6.5 2.6e-07 30.4 6.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM76438.1 - 2.7e-07 30.3 10.2 2.7e-07 30.3 10.2 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM76438.1 - 7.2e-06 25.8 8.2 1.6e-05 24.6 8.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFM76438.1 - 5.4e-05 23.1 6.0 0.00011 22.1 3.9 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 KFM76438.1 - 0.0012 18.9 5.8 0.0012 18.9 5.8 2.1 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KFM76438.1 - 0.0022 17.9 9.5 0.0022 17.9 9.5 1.9 2 0 0 2 2 1 1 zinc-RING finger domain PUB_1 PF18486.1 KFM76438.1 - 0.0042 16.9 0.0 0.0097 15.7 0.0 1.6 1 0 0 1 1 1 1 PNGase/UBA- or UBX-containing domain Baculo_IE-1 PF05290.11 KFM76438.1 - 0.0091 15.9 6.3 0.023 14.6 6.3 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 KFM76438.1 - 0.012 15.7 1.6 0.012 15.7 1.6 2.2 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFM76438.1 - 0.024 14.9 9.9 0.024 14.9 9.9 2.8 2 1 0 2 2 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFM76438.1 - 0.17 12.1 10.7 0.61 10.3 10.7 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Med19 PF10278.9 KFM76438.1 - 2.8 7.8 9.1 29 4.5 6.0 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 rve PF00665.26 KFM76439.1 - 2.2e-17 63.3 0.2 8.6e-17 61.4 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 KFM76439.1 - 9.8e-17 61.2 0.6 2.3e-16 60.0 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFM76439.1 - 3.4e-08 33.4 0.0 1.1e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM76439.1 - 4.6e-07 30.1 0.3 2e-06 28.0 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_IS240 PF13610.6 KFM76439.1 - 0.0094 16.2 1.0 0.026 14.8 1.0 1.7 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 KFM76439.1 - 0.06 13.1 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain COPI_C PF06957.11 KFM76440.1 - 9.5e-157 521.9 0.0 1.4e-156 521.3 0.0 1.3 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 KFM76440.1 - 2.3e-139 465.3 1.7 3.4e-139 464.7 1.7 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KFM76440.1 - 2.8e-38 129.2 22.2 5.8e-07 30.1 0.4 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM76440.1 - 1.1e-08 35.2 0.2 0.0013 18.9 0.0 4.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Helveticin_J PF17312.2 KFM76440.1 - 0.038 13.1 0.3 0.11 11.5 0.1 1.8 2 0 0 2 2 2 0 Bacteriocin helveticin-J Nup160 PF11715.8 KFM76440.1 - 0.31 9.6 6.6 1.8 7.1 0.1 3.6 2 1 2 4 4 4 0 Nucleoporin Nup120/160 DDE_3 PF13358.6 KFM76441.1 - 1.3e-07 31.5 0.0 2.1e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76442.1 - 3e-14 53.0 1.0 5.9e-14 52.1 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76442.1 - 7.7e-14 51.7 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76443.1 - 2.1e-16 59.9 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76443.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 KFM76444.1 - 5.1e-47 160.2 0.8 1.1e-46 159.1 0.8 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM76444.1 - 2.3e-17 62.9 3.3 3e-17 62.6 1.0 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM76444.1 - 1e-05 25.2 0.4 2.8e-05 23.8 0.4 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Neur_chan_memb PF02932.16 KFM76445.1 - 1.6e-34 120.0 4.6 2.1e-34 119.6 4.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM76445.1 - 2.1e-11 43.7 0.1 2.8e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1397 PF07165.11 KFM76446.1 - 0.061 12.7 0.4 0.07 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) SBF PF01758.16 KFM76447.1 - 6.4e-31 107.6 12.1 6.4e-31 107.6 12.1 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 KFM76447.1 - 0.014 13.9 8.6 0.26 9.6 4.2 2.7 2 2 0 2 2 2 0 Membrane transport protein BTB PF00651.31 KFM76448.1 - 9.1e-23 80.6 3.0 2.6e-22 79.2 1.3 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM76448.1 - 0.016 15.3 0.1 0.099 12.7 0.0 2.4 2 0 0 2 2 2 0 BTB And C-terminal Kelch Rhomboid PF01694.22 KFM76449.1 - 1.1e-22 80.7 7.7 1.2e-22 80.5 7.7 1.0 1 0 0 1 1 1 1 Rhomboid family Flp_Fap PF04964.14 KFM76449.1 - 2.7 7.9 6.1 0.26 11.1 0.4 2.2 2 1 0 2 2 2 0 Flp/Fap pilin component EF-hand_7 PF13499.6 KFM76450.1 - 4.8e-11 43.0 0.3 7.2e-11 42.4 0.3 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM76450.1 - 3.2e-10 38.8 0.0 0.00084 18.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM76450.1 - 1.4e-08 34.0 0.0 0.00035 20.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFM76450.1 - 7.2e-07 28.4 1.7 0.03 13.8 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFM76450.1 - 8.8e-05 22.3 1.1 0.00092 19.0 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 KFM76450.1 - 0.0055 17.0 0.1 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 KFM76450.1 - 0.0069 16.3 2.8 0.02 14.8 0.9 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Trep_dent_lipo PF09710.10 KFM76450.1 - 0.22 10.4 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Dockerin_1 PF00404.18 KFM76450.1 - 0.31 11.3 0.9 20 5.5 0.1 2.3 2 0 0 2 2 2 0 Dockerin type I domain Cadherin PF00028.17 KFM76451.1 - 1.3e-18 67.2 0.4 2.4e-08 34.3 0.0 3.5 3 0 0 3 3 3 3 Cadherin domain ChitinaseA_N PF08329.10 KFM76451.1 - 0.0087 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Chitinase A, N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 KFM76452.1 - 1.9e-16 60.0 2.3 4.4e-16 58.9 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76452.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76453.1 - 2.4e-16 59.7 2.2 4.5e-16 58.9 2.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76453.1 - 8.2e-14 51.6 0.0 1.6e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Ig_3 PF13927.6 KFM76454.1 - 2e-30 105.2 0.0 1.5e-14 54.3 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM76454.1 - 1.1e-25 89.5 0.0 7.7e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM76454.1 - 1.9e-18 66.4 0.0 7.1e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM76454.1 - 6e-17 61.7 0.0 8.5e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM76454.1 - 2.1e-08 34.3 0.0 0.0085 16.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFM76454.1 - 0.00051 20.0 0.0 0.21 11.6 0.0 3.0 4 0 0 4 4 4 1 C17orf99 Ig domain C2-set_2 PF08205.12 KFM76454.1 - 0.00068 19.6 0.6 0.098 12.7 0.0 3.3 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFM76455.1 - 4.5e-14 52.3 0.0 1.4e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM76455.1 - 7.6e-13 48.9 0.2 1.1e-11 45.1 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFM76455.1 - 3.1e-07 30.5 0.1 2.6e-06 27.5 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 KFM76455.1 - 3.2e-06 27.3 0.0 6.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM76455.1 - 1.2e-05 25.5 0.0 6.3e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM76455.1 - 0.0024 17.9 0.0 0.012 15.6 0.0 2.2 3 0 0 3 3 3 1 C17orf99 Ig domain HTH_Tnp_Tc3_2 PF01498.18 KFM76456.1 - 5.2e-16 58.6 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76456.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76456.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76456.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76456.1 - 0.024 14.7 0.4 0.092 12.9 0.4 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM76456.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain NIF PF03031.18 KFM76457.1 - 5.4e-54 182.2 0.3 6.2e-54 182.0 0.3 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CUT PF02376.15 KFM76458.1 - 3.1e-32 110.6 0.2 4.9e-32 109.9 0.2 1.3 1 0 0 1 1 1 1 CUT domain TFIIA PF03153.13 KFM76458.1 - 3.3 7.6 13.4 5 7.0 13.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serpin PF00079.20 KFM76460.1 - 6.2e-104 348.2 0.0 7.6e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) LRR_8 PF13855.6 KFM76463.1 - 1.1e-31 108.3 78.0 1.4e-09 37.5 5.9 3.3 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFM76463.1 - 3.5e-14 52.7 33.4 1e-06 28.9 6.3 4.3 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM76463.1 - 0.0023 18.2 24.1 1.1 10.1 0.1 6.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 KFM76463.1 - 0.005 16.4 13.8 0.088 12.3 1.9 2.8 1 1 2 3 3 3 3 Leucine-rich repeat Synapsin_N PF10581.9 KFM76463.1 - 0.061 13.3 0.2 0.28 11.2 0.1 2.1 2 0 0 2 2 2 0 Synapsin N-terminal DUF2322 PF10084.9 KFM76463.1 - 0.1 12.6 0.4 5.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) LEDGF PF11467.8 KFM76463.1 - 0.17 11.5 1.1 0.63 9.7 0.2 2.1 1 1 2 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) IL11 PF07400.11 KFM76463.1 - 0.77 9.4 4.6 0.92 9.1 1.0 2.1 1 1 0 2 2 2 0 Interleukin 11 Exo_endo_phos_2 PF14529.6 KFM76464.1 - 4.5e-08 33.0 0.0 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM76464.1 - 0.00084 18.9 0.1 0.001 18.6 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_Tnp_Tc5 PF03221.16 KFM76465.1 - 2.7e-13 49.7 0.6 6.3e-13 48.5 0.6 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM76465.1 - 1.3e-07 31.2 3.0 1.6e-07 30.9 1.5 1.9 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain DDE_1 PF03184.19 KFM76465.1 - 0.0053 16.4 0.0 0.023 14.4 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM76465.1 - 0.011 15.5 0.1 0.073 12.9 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain DUF5338 PF17273.2 KFM76465.1 - 0.068 13.3 0.2 2.8 8.1 0.0 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5338) HTH_38 PF13936.6 KFM76465.1 - 0.073 12.8 0.3 0.4 10.5 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MRP-S32 PF10210.9 KFM76465.1 - 0.082 13.5 0.3 0.23 12.0 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 DDE_1 PF03184.19 KFM76466.1 - 0.0002 21.0 0.3 0.00035 20.3 0.3 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease ASC PF00858.24 KFM76467.1 - 6.6e-56 190.1 13.3 7.5e-56 190.0 13.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 KFM76468.1 - 3.5e-11 42.7 0.4 5.1e-11 42.2 0.4 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel V1R PF03402.14 KFM76468.1 - 0.073 12.7 0.7 0.23 11.0 0.2 1.8 2 0 0 2 2 2 0 Vomeronasal organ pheromone receptor family, V1R DUF1940 PF09155.10 KFM76469.1 - 0.046 13.8 0.6 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) Ldl_recept_a PF00057.18 KFM76470.1 - 3.1e-09 36.9 8.0 7.2e-09 35.7 8.0 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A EphA2_TM PF14575.6 KFM76470.1 - 0.05 14.5 0.5 0.16 12.8 0.2 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ABC_tran PF00005.27 KFM76471.1 - 2.3e-17 63.8 0.0 3.4e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM76471.1 - 9.3e-06 25.2 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM76471.1 - 0.038 13.8 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KFM76473.1 - 2.3e-19 70.3 1.1 1.6e-18 67.6 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFM76473.1 - 0.00025 21.0 0.2 0.052 13.4 0.2 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM76473.1 - 0.0014 18.1 1.7 0.18 11.2 0.9 2.4 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFM76473.1 - 0.0088 16.6 1.5 3.6 8.1 0.2 2.2 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KFM76473.1 - 0.017 15.2 0.9 0.036 14.1 0.1 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase Vps39_1 PF10366.9 KFM76473.1 - 0.028 14.7 0.3 0.046 14.0 0.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 AAA_29 PF13555.6 KFM76473.1 - 0.037 13.8 0.7 0.075 12.8 0.7 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KFM76473.1 - 0.055 13.5 5.8 0.071 13.2 1.7 2.2 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KFM76473.1 - 0.091 12.7 0.6 0.19 11.6 0.6 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KFM76473.1 - 0.12 11.9 0.2 0.24 10.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM76473.1 - 0.15 12.4 1.6 0.4 11.1 1.6 2.0 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KFM76473.1 - 0.32 10.9 1.5 0.69 9.8 0.3 2.0 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 KFM76473.1 - 5.9 6.9 7.2 6.6 6.8 1.7 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain zf-CCCH PF00642.24 KFM76476.1 - 2.6e-13 49.5 22.0 8.8e-07 28.7 1.0 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFM76476.1 - 2e-08 34.4 8.2 8.1e-06 26.0 4.2 2.3 2 0 0 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 KFM76476.1 - 2.9e-08 33.5 31.8 5.3e-05 23.1 4.3 4.3 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFM76476.1 - 6.4e-08 32.2 23.9 0.00018 21.2 4.5 3.5 3 1 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 KFM76476.1 - 7.8e-05 23.3 13.8 0.028 15.1 0.4 3.2 1 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 KFM76476.1 - 0.00016 22.0 26.3 0.0057 17.1 2.3 3.4 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger ZapB PF06005.12 KFM76476.1 - 0.0081 16.6 6.0 0.017 15.5 6.0 1.5 1 0 0 1 1 1 1 Cell division protein ZapB KASH_CCD PF14662.6 KFM76476.1 - 0.0096 15.8 0.4 0.015 15.2 0.4 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_2 PF07716.15 KFM76476.1 - 0.013 15.5 6.6 0.016 15.3 3.3 2.3 1 1 1 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 KFM76476.1 - 0.043 14.1 2.2 0.082 13.2 0.8 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family BLOC1_2 PF10046.9 KFM76476.1 - 0.093 13.0 1.2 0.15 12.4 0.6 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RNA_pol_Rpb5_C PF01191.19 KFM76476.1 - 0.21 11.5 0.6 0.42 10.5 0.6 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain DivIC PF04977.15 KFM76476.1 - 0.33 10.7 2.5 0.65 9.8 2.5 1.5 1 0 0 1 1 1 0 Septum formation initiator Otopetrin PF03189.13 KFM76477.1 - 9.5e-34 117.0 1.1 1.4e-33 116.5 1.1 1.2 1 0 0 1 1 1 1 Otopetrin SPACA9 PF15120.6 KFM76478.1 - 0.02 14.7 0.7 0.02 14.7 0.7 1.1 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Ustilago_mating PF05722.12 KFM76478.1 - 0.074 12.6 0.2 0.08 12.5 0.2 1.0 1 0 0 1 1 1 0 Ustilago B locus mating-type protein DDE_3 PF13358.6 KFM76479.1 - 2.8e-11 43.4 0.0 3.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76480.1 - 2.7e-14 53.1 1.0 5.2e-14 52.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76480.1 - 6.6e-14 51.9 0.0 8.5e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease GMC_oxred_N PF00732.19 KFM76481.1 - 5.1e-09 35.9 0.0 5.7e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Jun PF03957.13 KFM76482.1 - 0.16 11.8 6.8 0.15 11.9 5.6 1.6 1 1 0 1 1 1 0 Jun-like transcription factor HTH_Tnp_Tc3_2 PF01498.18 KFM76484.1 - 3.7e-13 49.5 2.1 6.1e-13 48.8 1.0 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76484.1 - 4.1e-10 39.6 0.0 7.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM76484.1 - 0.028 15.0 8.4 0.19 12.4 1.6 3.0 3 0 0 3 3 3 0 Homeodomain-like domain SAM_1 PF00536.30 KFM76485.1 - 7.9e-12 45.4 0.1 9.9e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM76485.1 - 5.1e-06 26.5 0.1 6.6e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFM76485.1 - 8.3e-05 22.5 0.0 9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 KFM76485.1 - 0.01 16.1 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 0 Ste50p, sterile alpha motif DUF1685 PF07939.11 KFM76485.1 - 0.1 12.3 0.7 0.56 10.0 0.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1685) MBT PF02820.18 KFM76486.1 - 7.8e-57 189.5 1.3 1.1e-29 102.6 0.2 2.2 2 0 0 2 2 2 2 mbt repeat Tlr3_TMD PF17968.1 KFM76486.1 - 0.0016 18.5 0.3 1.8 8.8 0.1 2.4 2 0 0 2 2 2 2 Toll-like receptor 3 trans-membrane domain Tudor-knot PF11717.8 KFM76486.1 - 0.077 12.9 1.1 4.6 7.2 0.2 2.2 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain CsiD PF08943.10 KFM76486.1 - 0.31 10.1 0.5 8.9 5.3 0.2 2.1 2 0 0 2 2 2 0 CsiD MBT PF02820.18 KFM76487.1 - 2.7e-25 88.5 0.0 6.2e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 mbt repeat Glyco_hydro_2_N PF02837.18 KFM76487.1 - 0.11 12.3 0.0 0.72 9.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Dimer_Tnp_hAT PF05699.14 KFM76488.1 - 6.7e-10 38.6 0.1 2.4e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4371 PF14291.6 KFM76488.1 - 0.001 18.8 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) IFT57 PF10498.9 KFM76488.1 - 0.014 14.4 0.4 0.025 13.6 0.4 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PCMT PF01135.19 KFM76490.1 - 2.9e-22 79.5 0.0 4.5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 KFM76490.1 - 1.7e-05 25.1 1.7 0.082 13.3 0.4 2.5 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.13 KFM76490.1 - 0.00055 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KFM76490.1 - 0.015 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Homeodomain PF00046.29 KFM76491.1 - 3.1e-20 71.7 2.5 5.5e-20 71.0 2.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM76491.1 - 0.0045 16.9 0.2 0.01 15.7 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFM76491.1 - 0.14 12.0 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF2517 PF10725.9 KFM76492.1 - 0.16 11.7 1.9 0.33 10.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2517) DDE_3 PF13358.6 KFM76494.1 - 1.4e-08 34.6 0.0 1.9e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Trypan_glycop_C PF10659.9 KFM76494.1 - 0.22 11.9 11.0 0.45 10.9 11.0 1.6 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain DUF4726 PF15855.5 KFM76494.1 - 1.1 9.5 5.9 1.3 9.3 0.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4726) CDC45 PF02724.14 KFM76494.1 - 2.1 6.5 6.4 3.2 5.9 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein HTH_Tnp_Tc3_2 PF01498.18 KFM76495.1 - 3.5e-16 59.2 2.2 7.4e-16 58.2 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76495.1 - 1.8e-13 50.4 0.0 3.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 KFM76496.1 - 1.4e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KFM76496.1 - 9.9e-06 25.8 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNase H Membr_traf_MHD PF10540.9 KFM76500.1 - 0.00028 21.1 1.8 0.00031 20.9 1.8 1.1 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain L27_1 PF09058.10 KFM76500.1 - 0.04 13.9 0.2 0.043 13.8 0.2 1.1 1 0 0 1 1 1 0 L27_1 C2 PF00168.30 KFM76501.1 - 1.1e-16 61.0 0.0 1.6e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 C2 domain MIP PF00230.20 KFM76502.1 - 4.7e-34 118.1 1.5 5.6e-34 117.8 1.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein 7tm_2 PF00002.24 KFM76503.1 - 4.2e-21 75.3 20.5 4.2e-21 75.3 20.5 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.24 KFM76504.1 - 1.7e-19 70.1 25.6 2.6e-19 69.5 25.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 KFM76504.1 - 0.0019 17.6 22.2 0.0033 16.8 20.3 2.3 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Rax2 PF12768.7 KFM76504.1 - 0.015 14.8 0.2 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Cortical protein marker for cell polarity HRG PF16954.5 KFM76504.1 - 0.092 13.2 0.1 0.092 13.2 0.1 4.3 3 2 1 4 4 4 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF2269 PF10027.9 KFM76504.1 - 1.2 9.2 20.1 0.08 13.0 5.4 3.3 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2269) Tetraspanin PF00335.20 KFM76505.1 - 0.0013 18.5 0.7 0.0016 18.2 0.7 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4191 PF13829.6 KFM76505.1 - 0.036 13.4 0.3 0.04 13.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) B2-adapt-app_C PF09066.10 KFM76505.1 - 0.074 13.1 0.4 0.11 12.5 0.2 1.4 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain LRR19-TM PF15176.6 KFM76505.1 - 0.08 12.9 1.1 1.5 8.9 1.1 2.0 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Rax2 PF12768.7 KFM76505.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity 7tm_2 PF00002.24 KFM76506.1 - 3.4e-11 42.9 10.9 6.5e-11 42.0 10.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF5466 PF17554.2 KFM76506.1 - 0.035 14.3 0.5 0.078 13.2 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5466) OAD_gamma PF04277.13 KFM76506.1 - 1.4 9.6 3.0 4.7 7.9 3.0 1.9 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PAP_assoc PF03828.19 KFM76509.1 - 1.1e-14 54.4 0.1 2.9e-14 53.0 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase zf-CCHC PF00098.23 KFM76509.1 - 4.2e-06 26.6 25.2 2.5e-05 24.1 3.6 3.6 3 0 0 3 3 3 3 Zinc knuckle NTP_transf_2 PF01909.23 KFM76509.1 - 0.00053 20.2 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2990 PF11693.8 KFM76509.1 - 0.054 13.7 0.0 9.5 6.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) zf-CCHC_4 PF14392.6 KFM76509.1 - 0.18 11.5 15.0 0.74 9.6 1.1 3.4 3 0 0 3 3 3 0 Zinc knuckle Nop10p PF04135.12 KFM76511.1 - 0.0014 18.6 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NLE PF08154.12 KFM76511.1 - 0.0058 17.1 0.0 0.0079 16.7 0.0 1.2 1 0 0 1 1 1 1 NLE (NUC135) domain DUF89 PF01937.19 KFM76512.1 - 9.4e-100 334.0 3.4 1.3e-99 333.5 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 IDO PF01231.18 KFM76512.1 - 0.036 12.8 0.0 0.089 11.6 0.0 1.6 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase DTW PF03942.15 KFM76512.1 - 0.04 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 DTW domain Filament PF00038.21 KFM76513.1 - 9.6e-71 238.9 68.2 1.5e-68 231.7 68.2 2.2 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFM76513.1 - 1.4e-16 60.8 0.1 3.3e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Lamin Tail Domain Myosin_tail_1 PF01576.19 KFM76513.1 - 0.00034 18.6 68.2 0.0011 16.9 40.1 2.1 1 1 1 2 2 2 2 Myosin tail Spc7 PF08317.11 KFM76513.1 - 0.0009 18.2 61.6 0.0062 15.5 23.0 3.3 1 1 1 2 2 2 1 Spc7 kinetochore protein APG6_N PF17675.1 KFM76513.1 - 0.0012 19.4 25.9 0.0012 19.4 25.9 4.7 2 2 2 4 4 4 1 Apg6 coiled-coil region BLOC1_2 PF10046.9 KFM76513.1 - 0.0017 18.6 5.2 0.0017 18.6 5.2 5.7 3 2 3 6 6 6 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Striatin PF08232.12 KFM76513.1 - 0.0079 16.8 8.8 0.0079 16.8 8.8 4.0 1 1 2 3 3 2 1 Striatin family bZIP_1 PF00170.21 KFM76513.1 - 0.023 14.8 3.2 0.023 14.8 3.2 6.8 4 2 2 7 7 7 0 bZIP transcription factor DUF4407 PF14362.6 KFM76513.1 - 0.042 13.2 41.5 0.2 11.0 14.7 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 KFM76513.1 - 0.042 13.1 50.6 0.06 12.6 15.3 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF3450) FPP PF05911.11 KFM76513.1 - 0.13 10.4 61.3 0.1 10.7 29.0 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 KFM76513.1 - 0.18 12.0 69.8 0.036 14.3 22.5 5.2 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 KFM76513.1 - 0.61 9.8 32.8 0.055 13.2 13.9 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF745) DUF4618 PF15397.6 KFM76513.1 - 2.3 7.6 58.3 1 8.8 19.3 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4618) KASH_CCD PF14662.6 KFM76513.1 - 3.3 7.5 68.5 3.9 7.3 27.3 3.4 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH UPF0184 PF03670.13 KFM76513.1 - 6.9 7.1 18.2 0.16 12.4 2.5 4.2 4 2 1 5 5 4 0 Uncharacterised protein family (UPF0184) TPR_MLP1_2 PF07926.12 KFM76513.1 - 8.8 6.4 63.5 1.3 9.1 14.7 4.8 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein MAP7 PF05672.11 KFM76514.1 - 3.8e-20 72.2 82.0 3.8e-20 72.2 82.0 2.7 2 0 0 2 2 2 2 MAP7 (E-MAP-115) family SET PF00856.28 KFM76516.1 - 0.0006 20.2 0.1 0.0006 20.2 0.1 1.1 1 0 0 1 1 1 1 SET domain zf-H2C2_2 PF13465.6 KFM76517.1 - 8.1e-29 98.8 38.3 1e-07 32.0 1.0 5.9 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76517.1 - 2.1e-19 68.8 41.7 0.00014 22.1 4.0 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76517.1 - 1.4e-13 50.4 37.5 0.0035 18.0 3.4 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM76517.1 - 4.8e-07 29.6 37.0 0.0027 17.7 1.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KFM76517.1 - 7.6e-06 26.1 31.4 0.00097 19.5 1.3 6.0 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM76517.1 - 7.8e-06 26.0 21.9 0.0066 16.7 0.1 5.2 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM76517.1 - 0.00075 19.7 1.5 0.3 11.4 0.4 3.5 2 1 2 4 4 4 2 BolA-like protein Scramblase PF03803.15 KFM76517.1 - 0.13 11.6 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Scramblase zf-C2H2_2 PF12756.7 KFM76517.1 - 1.7 9.0 22.5 2.9 8.3 1.3 4.3 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFM76517.1 - 4.2 7.2 22.4 0.055 13.3 0.9 4.6 5 0 0 5 5 5 0 zinc-finger C2H2-type DUF4428 PF14471.6 KFM76517.1 - 5 7.1 12.4 0.12 12.3 0.6 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) HTH_32 PF13565.6 KFM76519.1 - 0.12 13.0 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Acyltransferase PF01553.21 KFM76522.1 - 3.8e-21 75.1 0.0 6.7e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DPPIV_rep PF18811.1 KFM76522.1 - 0.12 12.3 0.9 0.45 10.5 0.4 2.4 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region DUF826 PF05696.11 KFM76523.1 - 0.026 14.6 0.2 0.026 14.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF826) HTH_Tnp_Tc3_2 PF01498.18 KFM76524.1 - 2.6e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76524.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76525.1 - 7.5e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76525.1 - 2e-15 56.8 0.0 5.7e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM76525.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76525.1 - 0.0024 17.6 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76525.1 - 0.018 15.2 0.1 0.063 13.4 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM76525.1 - 0.033 14.2 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Ig_2 PF13895.6 KFM76526.1 - 9.9e-18 64.3 2.9 3.1e-05 24.2 0.1 4.1 3 3 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.6 KFM76526.1 - 5.3e-14 52.6 1.0 0.0037 17.8 0.0 3.7 3 1 1 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.12 KFM76526.1 - 1.3e-12 47.6 0.5 8.4e-08 32.2 0.0 2.9 2 1 1 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM76526.1 - 2.6e-08 34.0 0.6 0.0019 18.4 0.0 3.6 3 1 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 KFM76526.1 - 5.1e-05 23.4 0.7 1.1 9.4 0.0 4.5 4 1 0 4 4 4 1 Immunoglobulin domain Lep_receptor_Ig PF06328.11 KFM76526.1 - 0.012 15.6 0.6 0.91 9.5 0.0 2.8 2 1 0 2 2 2 0 Ig-like C2-type domain Ig_4 PF16680.5 KFM76526.1 - 0.029 14.6 0.5 8.7 6.7 0.0 3.9 4 1 1 5 5 5 0 T-cell surface glycoprotein CD3 delta chain HTH_Tnp_Tc3_2 PF01498.18 KFM76527.1 - 1.8e-16 60.1 2.2 4.4e-16 58.9 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76527.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PH PF00169.29 KFM76528.1 - 1.6e-07 31.8 0.2 2.1e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KFM76528.1 - 0.00026 21.0 0.1 0.00036 20.5 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 KFM76528.1 - 0.036 14.3 0.1 0.049 13.9 0.1 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain RhoGEF PF00621.20 KFM76529.1 - 1.4e-37 129.7 0.9 1.4e-37 129.7 0.9 2.9 2 1 0 2 2 2 1 RhoGEF domain Spectrin PF00435.21 KFM76529.1 - 2.6e-07 31.1 6.5 3e-06 27.7 0.2 3.6 3 1 0 3 3 3 1 Spectrin repeat DUF1959 PF09218.10 KFM76529.1 - 0.01 16.0 0.5 0.049 13.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) Laminin_II PF06009.12 KFM76529.1 - 0.052 13.6 2.0 3.2 7.8 0.3 2.9 2 0 0 2 2 2 0 Laminin Domain II ApoLp-III PF07464.11 KFM76529.1 - 1.3 9.1 4.2 1.7 8.7 0.3 2.8 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DDE_Tnp_IS1595 PF12762.7 KFM76531.1 - 3.7e-21 75.7 0.0 5.4e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Zn_ribbon_recom PF13408.6 KFM76531.1 - 0.00046 20.7 1.5 0.0012 19.3 1.5 1.7 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain DDE_Tnp_IS66 PF03050.14 KFM76531.1 - 0.0006 19.4 0.0 0.00084 18.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family DDE_3 PF13358.6 KFM76531.1 - 0.0079 16.0 0.0 0.05 13.4 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease Xan_ur_permease PF00860.20 KFM76533.1 - 0.059 12.0 2.1 0.06 12.0 2.1 1.0 1 0 0 1 1 1 0 Permease family Chordopox_G3 PF06129.12 KFM76533.1 - 0.15 12.8 3.5 0.22 12.2 3.5 1.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Ferlin_C PF16165.5 KFM76533.1 - 8 6.4 5.8 8.4 6.3 5.8 1.1 1 0 0 1 1 1 0 Ferlin C-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM76534.1 - 3.1e-09 36.9 0.2 3.2e-09 36.9 0.2 1.0 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76534.1 - 0.017 15.8 0.1 0.02 15.5 0.1 1.1 1 0 0 1 1 1 0 Homeodomain-like domain zf-C2H2 PF00096.26 KFM76535.1 - 1.1e-19 69.6 19.2 9.6e-07 28.9 0.2 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM76535.1 - 3e-16 59.0 6.7 1.6e-09 37.7 1.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM76535.1 - 6.3e-12 45.3 17.9 0.0017 19.0 3.5 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM76535.1 - 1.5e-10 41.1 12.0 0.0091 16.4 0.8 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM76535.1 - 1.2e-08 35.1 12.9 4e-05 23.8 2.5 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFM76535.1 - 1.1e-07 31.9 11.0 0.038 14.3 0.3 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM76535.1 - 1e-06 28.4 11.4 0.00014 21.5 3.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM76535.1 - 6.1e-05 22.9 18.3 0.13 12.3 0.9 3.4 3 1 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.15 KFM76535.1 - 9.8e-05 22.3 16.0 0.0084 16.1 3.7 3.2 1 1 2 3 3 3 2 BED zinc finger zf-C2HC_2 PF13913.6 KFM76535.1 - 0.00023 21.0 10.2 0.42 10.6 0.1 3.2 3 0 0 3 3 3 3 zinc-finger of a C2HC-type GAGA PF09237.11 KFM76535.1 - 0.00049 19.8 1.3 4.1 7.3 0.1 3.2 1 1 2 3 3 3 0 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM76535.1 - 0.00065 19.7 4.9 0.73 9.9 0.7 3.1 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger Prok-RING_1 PF14446.6 KFM76535.1 - 0.00087 19.2 2.2 5.5 7.0 0.0 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-MYST PF17772.1 KFM76535.1 - 0.0015 18.1 5.5 0.98 9.1 0.7 3.1 1 1 2 3 3 3 1 MYST family zinc finger domain zf_UBZ PF18439.1 KFM76535.1 - 0.0018 17.8 4.0 1.4 8.5 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 KFM76535.1 - 0.0019 18.3 4.8 5.5 7.2 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C4_ClpX PF06689.13 KFM76535.1 - 0.0026 17.6 3.8 0.053 13.4 0.0 2.9 2 1 1 3 3 3 1 ClpX C4-type zinc finger zinc_ribbon_15 PF17032.5 KFM76535.1 - 0.0073 17.0 3.5 0.16 12.8 0.2 2.1 1 1 0 2 2 2 1 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM76535.1 - 0.0079 16.0 5.2 4.5 7.2 0.0 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) HypA PF01155.19 KFM76535.1 - 0.011 15.8 2.2 0.9 9.6 0.6 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KFM76535.1 - 0.014 15.7 1.8 9.6 6.6 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon CpXC PF14353.6 KFM76535.1 - 0.014 15.4 3.1 1.6 8.8 0.5 2.9 1 1 2 3 3 3 0 CpXC protein zf-C2H2_2 PF12756.7 KFM76535.1 - 0.019 15.3 9.9 0.4 11.0 0.9 3.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 KFM76535.1 - 0.019 15.2 1.0 0.019 15.2 1.0 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain DUF3268 PF11672.8 KFM76535.1 - 0.022 15.1 1.4 0.35 11.2 0.1 2.1 1 1 1 2 2 2 0 zinc-finger-containing domain zf-C2HE PF16278.5 KFM76535.1 - 0.024 15.1 16.4 0.65 10.5 5.2 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KFM76535.1 - 0.025 14.7 4.1 0.7 10.1 2.1 2.4 1 1 2 3 3 3 0 Zinc ribbon domain DZR PF12773.7 KFM76535.1 - 0.027 14.5 4.7 0.52 10.4 4.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon ADK_lid PF05191.14 KFM76535.1 - 0.028 14.4 4.4 0.038 14.0 0.6 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF2039 PF10217.9 KFM76535.1 - 0.035 14.4 3.2 0.13 12.6 3.2 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) NMD3 PF04981.13 KFM76535.1 - 0.041 13.3 0.6 0.52 9.7 0.0 2.3 1 1 1 2 2 2 0 NMD3 family LIM PF00412.22 KFM76535.1 - 0.048 13.9 5.1 4.2 7.7 2.5 2.9 2 1 0 2 2 2 0 LIM domain NADH-G_4Fe-4S_3 PF10588.9 KFM76535.1 - 0.071 12.7 2.7 2.2 7.9 0.1 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Cript PF10235.9 KFM76535.1 - 0.072 13.7 4.4 0.75 10.4 0.8 2.4 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT zf-C2H2_3rep PF18868.1 KFM76535.1 - 0.084 13.5 6.8 0.4 11.4 0.4 2.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats FYVE PF01363.21 KFM76535.1 - 0.1 12.7 10.0 0.22 11.7 1.6 2.3 1 1 1 2 2 2 0 FYVE zinc finger OSTMP1 PF09777.9 KFM76535.1 - 0.11 11.9 4.2 0.89 8.9 0.8 2.2 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor Vps39_2 PF10367.9 KFM76535.1 - 0.11 12.9 8.2 7.4 7.1 0.2 3.1 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-nanos PF05741.13 KFM76535.1 - 0.14 12.4 5.3 4.8 7.5 2.4 2.4 2 1 0 2 2 2 0 Nanos RNA binding domain HNH PF01844.23 KFM76535.1 - 0.16 12.2 6.7 0.29 11.3 0.4 3.0 3 0 0 3 3 3 0 HNH endonuclease zf-RING_5 PF14634.6 KFM76535.1 - 0.19 11.7 8.2 12 5.9 4.8 3.0 2 1 0 2 2 2 0 zinc-RING finger domain zinc-ribbons_6 PF07191.12 KFM76535.1 - 0.2 11.7 4.2 4.4 7.4 4.2 2.4 1 1 0 1 1 1 0 zinc-ribbons zf-trcl PF13451.6 KFM76535.1 - 0.23 11.4 3.3 7.9 6.5 0.1 2.9 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-AN1 PF01428.16 KFM76535.1 - 0.26 11.5 11.7 4.5 7.5 0.7 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger DUF4764 PF15961.5 KFM76535.1 - 0.27 9.9 6.0 0.43 9.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) DUF4428 PF14471.6 KFM76535.1 - 0.29 11.1 9.5 1.7 8.7 0.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4428) UBZ_FAAP20 PF15750.5 KFM76535.1 - 0.3 11.1 7.0 25 4.9 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Elf1 PF05129.13 KFM76535.1 - 0.34 11.0 5.2 0.1 12.7 1.2 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn-C2H2_12 PF18112.1 KFM76535.1 - 0.43 11.1 9.5 4.5 7.8 0.1 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Zf_RING PF16744.5 KFM76535.1 - 0.44 10.7 4.7 2.8 8.1 0.1 2.8 1 1 2 3 3 3 0 KIAA1045 RING finger zf-C2H2_11 PF16622.5 KFM76535.1 - 0.74 9.6 18.0 3 7.7 3.5 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-RING_4 PF14570.6 KFM76535.1 - 1.4 8.7 5.7 1.9 8.3 2.8 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain FYDLN_acid PF09538.10 KFM76535.1 - 1.6 9.4 7.2 7.4 7.3 1.2 2.9 2 1 1 3 3 2 0 Protein of unknown function (FYDLN_acid) Zn_Tnp_IS1595 PF12760.7 KFM76535.1 - 1.7 8.7 7.7 6.9 6.7 3.9 2.8 1 1 2 3 3 3 0 Transposase zinc-ribbon domain PHD PF00628.29 KFM76535.1 - 2.8 7.9 8.3 10 6.1 2.7 2.7 1 1 0 2 2 2 0 PHD-finger zf-C2H2 PF00096.26 KFM76536.1 - 6.7e-20 70.4 34.8 6.3e-06 26.4 0.7 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM76536.1 - 5.8e-17 61.3 37.1 1.3e-09 38.0 4.4 6.6 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM76536.1 - 2.9e-16 58.8 32.8 0.00011 22.7 0.5 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-met PF12874.7 KFM76536.1 - 9.9e-12 44.8 21.6 0.00085 19.6 0.1 5.3 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM76536.1 - 4.4e-10 39.6 16.9 0.015 15.6 0.7 5.3 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM76536.1 - 3.2e-06 27.0 29.9 0.0023 17.9 2.4 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM76536.1 - 4.1e-06 26.4 18.7 0.022 14.5 0.3 4.4 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM76536.1 - 1.5e-05 25.2 8.6 0.046 14.0 0.7 4.0 2 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFM76536.1 - 4.4e-05 23.8 10.4 0.97 9.8 0.1 4.2 2 1 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFM76536.1 - 0.00016 21.3 13.9 1.4 8.7 0.5 4.5 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM76536.1 - 0.0003 20.6 16.9 0.028 14.3 0.2 4.5 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM76536.1 - 0.0017 17.9 10.7 0.29 10.8 0.0 4.6 3 2 2 5 5 5 1 MYST family zinc finger domain DUF2256 PF10013.9 KFM76536.1 - 0.0059 16.7 14.8 0.65 10.2 0.1 4.6 5 0 0 5 5 4 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_3rep PF18868.1 KFM76536.1 - 0.0087 16.7 11.7 0.44 11.2 0.7 3.8 1 1 3 4 4 4 1 Zinc finger C2H2-type, 3 repeats PyrI_C PF02748.15 KFM76536.1 - 0.0093 15.9 0.5 0.0093 15.9 0.5 3.1 3 1 1 4 4 4 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain Prok-RING_1 PF14446.6 KFM76536.1 - 0.012 15.5 5.3 15 5.6 0.1 4.2 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 KFM76536.1 - 0.014 15.3 7.1 1.3 9.0 0.3 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM76536.1 - 0.018 14.8 9.0 0.18 11.7 0.1 3.8 2 1 2 4 4 4 0 GAGA factor HNH_5 PF14279.6 KFM76536.1 - 0.019 14.8 11.1 3.5 7.6 0.3 4.5 3 1 1 4 4 4 0 HNH endonuclease zinc_ribbon_15 PF17032.5 KFM76536.1 - 0.079 13.7 7.8 0.16 12.7 0.3 2.9 1 1 1 3 3 3 0 zinc-ribbon family BolA PF01722.18 KFM76536.1 - 0.088 13.1 0.4 28 5.1 0.0 3.0 2 1 0 2 2 2 0 BolA-like protein zf-C2HE PF16278.5 KFM76536.1 - 0.09 13.2 14.6 6.8 7.2 0.2 4.2 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CHCC PF10276.9 KFM76536.1 - 0.093 12.8 1.0 0.093 12.8 1.0 3.4 4 0 0 4 4 4 0 Zinc-finger domain HNH PF01844.23 KFM76536.1 - 0.13 12.5 12.6 0.71 10.1 0.2 4.1 4 0 0 4 4 4 0 HNH endonuclease HypA PF01155.19 KFM76536.1 - 0.18 11.8 3.7 0.73 9.9 3.7 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_9 PF16293.5 KFM76536.1 - 0.19 11.6 3.0 16 5.4 0.1 3.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-Dof PF02701.15 KFM76536.1 - 0.22 11.7 12.7 0.33 11.1 0.1 4.1 2 1 2 4 4 4 0 Dof domain, zinc finger zf_UBZ PF18439.1 KFM76536.1 - 0.27 10.9 7.8 5 6.8 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM76536.1 - 1.3 9.2 11.8 4.1 7.6 0.4 3.7 3 1 2 5 5 5 0 Zinc ribbon domain XPA_N PF01286.18 KFM76536.1 - 2 8.5 9.2 26 5.0 0.1 3.9 4 0 0 4 4 4 0 XPA protein N-terminal DUF4764 PF15961.5 KFM76536.1 - 2.7 6.6 8.4 1 8.0 0.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4764) zf-BED PF02892.15 KFM76536.1 - 3.2 7.8 30.0 0.25 11.4 3.7 4.9 4 1 2 6 6 5 0 BED zinc finger Sprouty PF05210.13 KFM76536.1 - 4.8 7.6 8.7 9.9 6.6 1.9 3.4 2 1 0 3 3 3 0 Sprouty protein (Spry) zf-H2C2_2 PF13465.6 KFM76537.1 - 1e-16 60.5 17.1 4.3e-09 36.4 0.2 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76537.1 - 1.3e-11 44.3 23.6 0.00011 22.5 0.9 3.7 5 0 0 5 5 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76537.1 - 9.2e-11 41.6 20.2 0.00074 20.1 1.6 3.6 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM76537.1 - 6.9e-09 35.8 12.9 0.0033 17.8 0.9 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM76537.1 - 4.3e-05 23.7 5.4 0.0014 18.9 1.7 2.4 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFM76537.1 - 0.00026 21.2 8.0 0.16 12.3 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM76537.1 - 0.0012 18.6 4.6 0.0012 18.6 4.6 3.2 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM76537.1 - 0.0014 18.6 14.6 0.13 12.3 0.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-MYST PF17772.1 KFM76537.1 - 0.0069 16.0 4.5 5.6 6.7 0.2 3.2 2 1 1 3 3 3 1 MYST family zinc finger domain DUF2256 PF10013.9 KFM76537.1 - 0.0086 16.2 2.7 16 5.7 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Sec23_Sec24 PF04810.15 KFM76537.1 - 0.0099 15.9 9.0 0.093 12.8 0.7 3.2 1 1 2 3 3 3 1 Sec23/Sec24 zinc finger zf-C2H2_3rep PF18868.1 KFM76537.1 - 0.015 16.0 8.6 0.93 10.2 1.0 3.0 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-CCHC_2 PF13696.6 KFM76537.1 - 0.018 14.9 2.2 0.018 14.9 2.2 3.6 4 0 0 4 4 4 0 Zinc knuckle GAGA PF09237.11 KFM76537.1 - 0.032 14.0 5.9 5.7 6.8 1.0 3.1 1 1 2 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.7 KFM76537.1 - 0.085 13.2 8.1 6 7.3 0.2 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) HypA PF01155.19 KFM76537.1 - 0.091 12.8 2.9 0.15 12.1 2.5 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HE PF16278.5 KFM76537.1 - 0.18 12.3 10.7 7 7.2 0.4 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KFM76537.1 - 0.25 11.5 5.2 2.1 8.5 1.2 3.3 2 1 0 2 2 2 0 Zinc ribbon domain zf-LYAR PF08790.11 KFM76537.1 - 0.42 10.6 8.2 5.8 6.9 0.2 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 KFM76537.1 - 0.99 9.4 14.8 0.28 11.1 0.6 3.4 1 1 2 3 3 3 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 KFM76537.1 - 1.5 8.5 8.2 8.6 6.0 0.1 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 KFM76537.1 - 2 8.5 5.4 1.5 8.9 0.1 2.5 1 1 1 2 2 2 0 CpXC protein Actin_micro PF17003.5 KFM76537.1 - 2.7 7.1 5.1 15 4.6 1.3 2.4 1 1 2 3 3 3 0 Putative actin-like family Vps39_2 PF10367.9 KFM76537.1 - 8.3 6.9 8.2 10 6.6 0.1 3.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C2H2 PF00096.26 KFM76539.1 - 7e-10 38.8 6.4 1.9e-05 24.8 1.3 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM76539.1 - 1.6e-07 31.4 7.9 8e-05 22.9 0.3 2.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM76539.1 - 5.8e-07 29.8 6.5 0.0058 17.4 1.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM76539.1 - 3.8e-05 23.3 2.2 0.0036 17.0 0.5 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-met PF12874.7 KFM76539.1 - 0.028 14.8 7.4 0.056 13.8 2.0 2.4 2 1 0 2 2 2 0 Zinc-finger of C2H2 type DUF2180 PF09947.9 KFM76539.1 - 0.035 14.1 1.1 0.041 13.9 1.1 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2HE PF16278.5 KFM76539.1 - 0.064 13.7 5.9 0.13 12.7 1.3 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KFM76539.1 - 0.092 12.5 1.0 0.092 12.5 1.0 2.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain HTH_48 PF17906.1 KFM76540.1 - 0.031 14.4 0.3 0.042 14.0 0.3 1.2 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Zn_ribbon_recom PF13408.6 KFM76541.1 - 0.024 15.2 0.9 0.036 14.6 0.9 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Frizzled PF01534.17 KFM76541.1 - 0.042 12.9 0.9 0.045 12.8 0.9 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DDE_3 PF13358.6 KFM76542.1 - 3.1e-06 27.0 0.1 6.9e-06 25.9 0.1 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease EF-hand_13 PF17958.1 KFM76542.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain HTH_Tnp_Tc3_2 PF01498.18 KFM76543.1 - 1.8e-17 63.4 0.9 3.2e-17 62.5 0.9 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76543.1 - 2.2e-06 28.2 2.3 2.2e-06 28.2 2.3 1.8 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM76543.1 - 0.00041 20.2 0.3 0.056 13.3 0.0 2.6 2 1 0 2 2 2 1 MarR family HTH_3 PF01381.22 KFM76543.1 - 0.00083 19.4 0.5 0.055 13.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM76543.1 - 0.003 17.5 0.6 0.04 13.9 0.0 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain PAX PF00292.18 KFM76543.1 - 0.021 14.7 0.0 0.14 12.1 0.0 2.1 2 1 0 2 2 2 0 'Paired box' domain HTH_24 PF13412.6 KFM76543.1 - 0.025 14.2 0.6 1.4 8.6 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KFM76543.1 - 0.034 14.3 0.8 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 KFM76543.1 - 0.1 13.0 0.4 8.6 6.9 0.2 2.5 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 KFM76543.1 - 0.17 11.7 2.6 2.4 8.1 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain N_BRCA1_IG PF16158.5 KFM76544.1 - 1.1e-27 96.8 0.2 2.8e-27 95.4 0.2 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KFM76544.1 - 4.4e-08 32.8 10.9 7.9e-08 32.0 7.9 2.7 3 0 0 3 3 3 1 Zinc finger, ZZ type C1_2 PF03107.16 KFM76544.1 - 0.0081 16.5 12.1 0.055 13.8 10.0 2.7 2 0 0 2 2 2 1 C1 domain GDPD_2 PF13653.6 KFM76547.1 - 9e-06 26.0 0.7 7.9e-05 23.0 0.1 2.5 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 KFM76547.1 - 0.00047 20.0 0.0 0.022 14.5 0.1 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family HTH_Tnp_Tc3_2 PF01498.18 KFM76548.1 - 1.5e-09 38.0 0.2 1.7e-09 37.8 0.2 1.1 1 0 0 1 1 1 1 Transposase Cpn60_TCP1 PF00118.24 KFM76549.1 - 1.2e-157 525.6 7.1 1.3e-157 525.4 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AadA_C PF18280.1 KFM76549.1 - 0.042 14.0 0.2 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Aminoglycoside adenyltransferase C-terminal domain zf-CCHC PF00098.23 KFM76550.1 - 9.3e-06 25.5 2.0 9.3e-06 25.5 2.0 1.8 2 0 0 2 2 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KFM76550.1 - 7.5e-05 22.5 1.9 0.00018 21.3 1.9 1.7 1 0 0 1 1 1 1 Zinc knuckle NPV_P10 PF05531.12 KFM76550.1 - 0.0011 19.4 2.7 0.015 15.7 0.7 3.2 3 1 0 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KFM76550.1 - 0.0014 19.1 2.6 0.0014 19.1 2.6 2.4 3 0 0 3 3 2 1 Protein of unknown function DUF16 Apolipoprotein PF01442.18 KFM76550.1 - 0.0046 16.9 7.1 0.0046 16.9 7.1 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain PNMA PF14893.6 KFM76550.1 - 0.0047 16.4 1.9 0.0063 15.9 1.9 1.2 1 0 0 1 1 1 1 PNMA DUF4795 PF16043.5 KFM76550.1 - 0.0052 16.4 4.7 0.0052 16.4 4.7 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) EzrA PF06160.12 KFM76550.1 - 0.0057 14.9 4.5 0.0092 14.2 4.5 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 KFM76550.1 - 0.015 15.4 0.5 0.09 12.8 0.1 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC53 PF10152.9 KFM76550.1 - 0.015 15.7 1.7 0.021 15.2 1.6 1.4 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex FlaC_arch PF05377.11 KFM76550.1 - 0.027 14.8 4.7 0.027 14.8 4.7 3.0 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) ApoLp-III PF07464.11 KFM76550.1 - 0.032 14.3 7.2 0.038 14.1 4.7 2.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) HSBP1 PF06825.12 KFM76550.1 - 0.034 14.0 0.3 0.27 11.1 0.3 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 ABC_tran_CTD PF16326.5 KFM76550.1 - 0.048 13.9 0.7 0.048 13.9 0.7 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain Bacillus_HBL PF05791.11 KFM76550.1 - 0.063 13.1 0.4 0.063 13.1 0.4 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) COG2 PF06148.11 KFM76550.1 - 0.067 13.3 8.2 0.045 13.8 4.4 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.10 KFM76550.1 - 0.068 13.4 1.6 0.26 11.5 0.4 2.4 3 0 0 3 3 2 0 Fibrinogen alpha/beta chain family MAP65_ASE1 PF03999.12 KFM76550.1 - 0.069 11.8 4.8 0.12 11.0 4.7 1.4 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4988 PF16378.5 KFM76550.1 - 0.071 12.8 0.4 0.17 11.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF1664 PF07889.12 KFM76550.1 - 0.071 13.1 8.3 0.087 12.9 2.4 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) ApoO PF09769.9 KFM76550.1 - 0.075 13.0 1.9 0.98 9.4 0.1 2.6 2 1 1 3 3 2 0 Apolipoprotein O DUF948 PF06103.11 KFM76550.1 - 0.081 13.2 3.2 1.2 9.4 0.4 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 KFM76550.1 - 0.087 12.4 7.0 0.15 11.6 3.0 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit Prefoldin_3 PF13758.6 KFM76550.1 - 0.1 12.6 4.5 1.3 9.2 0.7 3.2 3 1 0 3 3 2 0 Prefoldin subunit BLOC1_2 PF10046.9 KFM76550.1 - 0.11 12.8 4.9 0.086 13.1 1.8 2.3 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 End3 PF12761.7 KFM76550.1 - 0.12 12.5 2.8 0.16 12.1 1.1 2.0 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 UPF0184 PF03670.13 KFM76550.1 - 0.14 12.5 0.4 0.38 11.2 0.4 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Tup_N PF08581.10 KFM76550.1 - 0.17 12.2 2.7 0.52 10.7 2.7 1.9 1 0 0 1 1 1 0 Tup N-terminal Cauli_AT PF03233.13 KFM76550.1 - 0.17 11.8 2.4 0.45 10.4 2.4 1.7 1 0 0 1 1 1 0 Aphid transmission protein YabA PF06156.13 KFM76550.1 - 0.18 12.5 5.7 0.82 10.3 0.5 2.8 1 1 1 2 2 2 0 Initiation control protein YabA CK2S PF15011.6 KFM76550.1 - 0.22 11.4 3.3 1.5 8.7 0.6 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate Laminin_II PF06009.12 KFM76550.1 - 0.24 11.4 3.8 0.16 12.0 1.4 2.0 2 0 0 2 2 1 0 Laminin Domain II Prominin PF05478.11 KFM76550.1 - 0.24 9.3 3.3 0.11 10.4 1.2 1.5 2 0 0 2 2 2 0 Prominin Tom5 PF10642.9 KFM76550.1 - 0.32 11.0 2.0 15 5.7 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Tropomyosin_1 PF12718.7 KFM76550.1 - 0.36 11.0 9.3 0.071 13.3 5.3 1.9 2 0 0 2 2 1 0 Tropomyosin like Prefoldin_2 PF01920.20 KFM76550.1 - 0.38 10.7 9.1 0.065 13.2 2.7 2.7 2 1 0 2 2 2 0 Prefoldin subunit DUF1451 PF07295.11 KFM76550.1 - 0.4 10.7 6.7 0.075 13.1 1.2 2.6 2 1 1 3 3 3 0 Zinc-ribbon containing domain CLZ PF16526.5 KFM76550.1 - 0.41 11.0 4.6 1.2 9.6 0.4 3.3 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 KFM76550.1 - 0.42 10.7 8.4 0.1 12.6 2.9 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Osmo_CC PF08946.10 KFM76550.1 - 0.56 10.5 8.6 11 6.3 0.4 3.4 2 1 1 3 3 2 0 Osmosensory transporter coiled coil TMPIT PF07851.13 KFM76550.1 - 0.6 9.3 3.6 0.5 9.6 2.3 1.4 1 1 0 1 1 1 0 TMPIT-like protein Matrilin_ccoil PF10393.9 KFM76550.1 - 0.6 10.0 5.3 5.1 7.0 0.1 3.5 4 0 0 4 4 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Spectrin PF00435.21 KFM76550.1 - 0.73 10.4 4.4 0.82 10.2 1.5 2.4 2 0 0 2 2 2 0 Spectrin repeat XhlA PF10779.9 KFM76550.1 - 0.73 10.1 9.3 0.41 10.9 3.8 3.0 3 1 0 3 3 2 0 Haemolysin XhlA Spc7 PF08317.11 KFM76550.1 - 0.74 8.6 10.3 0.14 11.0 6.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein LOH1CR12 PF10158.9 KFM76550.1 - 0.91 9.6 5.0 0.64 10.1 3.2 1.7 2 0 0 2 2 1 0 Tumour suppressor protein Phasin PF05597.11 KFM76550.1 - 1.1 9.3 8.2 1.9 8.5 4.3 3.1 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.7 KFM76550.1 - 1.3 9.6 5.6 7.6 7.2 5.6 2.5 1 1 0 1 1 1 0 YtxH-like protein Snapin_Pallidin PF14712.6 KFM76550.1 - 1.5 9.3 9.7 0.5 10.8 1.4 3.1 3 1 1 4 4 2 0 Snapin/Pallidin DUF148 PF02520.17 KFM76550.1 - 1.5 9.0 5.9 7.5 6.7 0.6 2.7 2 1 1 3 3 2 0 Domain of unknown function DUF148 DUF724 PF05266.14 KFM76550.1 - 2.3 8.0 8.1 0.97 9.2 4.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fzo_mitofusin PF04799.13 KFM76550.1 - 2.4 7.7 5.2 0.97 9.0 1.8 2.1 2 1 0 2 2 2 0 fzo-like conserved region ZapB PF06005.12 KFM76550.1 - 5.2 7.6 8.3 31 5.1 0.2 3.2 2 1 0 2 2 2 0 Cell division protein ZapB DUF1640 PF07798.11 KFM76550.1 - 8.5 6.4 9.3 1.9 8.5 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) IHO1 PF15771.5 KFM76551.1 - 0.019 13.8 0.3 0.019 13.8 0.3 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 zf-CpG_bind_C PF12269.8 KFM76551.1 - 0.092 12.5 6.5 0.081 12.7 5.4 1.5 1 1 0 1 1 1 0 CpG binding protein zinc finger C terminal domain RVT_1 PF00078.27 KFM76552.1 - 4.8e-10 39.3 0.0 6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MORN PF02493.20 KFM76553.1 - 3.7e-35 117.7 62.3 1.7e-05 24.4 2.0 8.9 9 0 0 9 9 9 8 MORN repeat HTH_Tnp_Tc3_2 PF01498.18 KFM76555.1 - 7.9e-11 42.0 0.2 1.2e-10 41.5 0.2 1.2 1 0 0 1 1 1 1 Transposase MarR_2 PF12802.7 KFM76555.1 - 0.00032 20.5 0.1 0.012 15.5 0.0 2.6 2 1 0 2 2 2 1 MarR family HTH_7 PF02796.15 KFM76555.1 - 0.0053 16.8 0.1 0.063 13.4 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM76555.1 - 0.085 12.7 1.2 0.24 11.2 0.0 2.3 3 0 0 3 3 3 0 Homeodomain-like domain PAX PF00292.18 KFM76555.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain GCP_C_terminal PF04130.13 KFM76556.1 - 2.8e-28 99.3 8.0 3.3e-28 99.0 8.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFM76558.1 - 1.6e-10 41.1 0.9 1.8e-10 40.9 0.9 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Thymidylat_synt PF00303.19 KFM76558.1 - 0.00048 19.4 2.2 0.018 14.2 0.2 2.0 1 1 1 2 2 2 2 Thymidylate synthase DUF4180 PF13788.6 KFM76558.1 - 0.019 14.9 0.0 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4180) FliJ PF02050.16 KFM76558.1 - 0.043 14.0 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein NPV_P10 PF05531.12 KFM76558.1 - 0.045 14.2 0.5 0.13 12.7 0.2 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PAP_assoc PF03828.19 KFM76561.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Cid1 family poly A polymerase DUF3903 PF13043.6 KFM76561.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) DDE_3 PF13358.6 KFM76562.1 - 6.7e-06 25.9 0.0 8e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FhuF PF06276.12 KFM76562.1 - 0.014 15.8 0.1 0.022 15.2 0.1 1.3 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Oxysterol_BP PF01237.18 KFM76563.1 - 2.5e-25 89.1 0.1 2.5e-25 89.1 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Dscam_C PF12355.8 KFM76563.1 - 0.1 13.6 3.1 0.15 13.0 3.1 1.2 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Oxysterol_BP PF01237.18 KFM76564.1 - 1.5e-05 24.0 0.0 1.6e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein HTH_Tnp_Tc3_2 PF01498.18 KFM76565.1 - 7.5e-16 58.2 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76565.1 - 9.1e-16 57.9 0.1 5.3e-15 55.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM76565.1 - 0.00068 20.2 1.5 0.00068 20.2 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76565.1 - 0.0029 17.3 0.3 0.11 12.3 0.0 3.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76565.1 - 0.011 15.8 0.1 0.062 13.4 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM76565.1 - 0.032 14.2 2.6 0.033 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM76566.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76566.1 - 9.7e-14 51.4 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76567.1 - 4.8e-16 58.8 3.5 5.7e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76567.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76567.1 - 2e-07 30.7 1.2 7e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76567.1 - 0.0027 17.5 0.6 0.0075 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76567.1 - 2.3 8.9 15.6 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ion_trans PF00520.31 KFM76568.1 - 1.7e-09 37.2 0.2 2.3e-09 36.9 0.2 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KFM76569.1 - 1.2e-13 50.9 0.5 1.4e-13 50.7 0.5 1.1 1 0 0 1 1 1 1 Ion transport protein TssO PF17561.2 KFM76569.1 - 0.026 14.6 0.1 0.035 14.2 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO SARAF PF06682.12 KFM76569.1 - 0.027 14.1 0.0 0.028 14.1 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PKD_channel PF08016.12 KFM76569.1 - 0.032 12.9 0.8 0.035 12.8 0.8 1.1 1 0 0 1 1 1 0 Polycystin cation channel DUF2973 PF11189.8 KFM76569.1 - 0.086 12.9 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) TMEM208_SND2 PF05620.11 KFM76569.1 - 0.087 12.6 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 NicO PF03824.16 KFM76569.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein TMEM154 PF15102.6 KFM76569.1 - 0.19 11.7 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family TMEM52 PF14979.6 KFM76569.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 ETRAMP PF09716.10 KFM76569.1 - 0.45 10.6 3.5 0.97 9.5 3.5 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ion_trans PF00520.31 KFM76570.1 - 1.5e-50 171.7 9.0 1.8e-50 171.5 9.0 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM76570.1 - 2.6e-14 52.8 10.6 6.9e-10 38.2 2.3 2.5 1 1 1 2 2 2 2 Polycystin cation channel Peptidase_S49_N PF08496.10 KFM76570.1 - 0.058 13.5 1.3 0.12 12.4 1.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal APH PF01636.23 KFM76572.1 - 0.059 13.3 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Inhibitor_I24 PF10465.9 KFM76572.1 - 0.072 13.1 0.0 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 PinA peptidase inhibitor ABC1 PF03109.16 KFM76573.1 - 6.4e-36 123.1 0.1 1.2e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 ABC1 family HTH_Tnp_Tc3_2 PF01498.18 KFM76575.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76575.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.18 KFM76577.1 - 0.072 13.0 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain DUF229 PF02995.17 KFM76579.1 - 3.9e-121 405.1 0.0 1.4e-119 400.0 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF229) Sulfatase PF00884.23 KFM76579.1 - 0.00037 20.0 0.3 0.0038 16.7 0.1 2.1 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KFM76579.1 - 0.004 16.8 0.0 0.025 14.2 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DDE_3 PF13358.6 KFM76580.1 - 7.4e-17 61.5 0.1 3e-15 56.2 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76580.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase RhoGAP PF00620.27 KFM76581.1 - 1.6e-16 60.5 0.0 1.8e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain GLE1 PF07817.13 KFM76581.1 - 0.012 14.8 0.2 0.018 14.2 0.2 1.2 1 0 0 1 1 1 0 GLE1-like protein DUF4371 PF14291.6 KFM76582.1 - 7e-06 25.9 1.7 8.6e-06 25.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) COesterase PF00135.28 KFM76584.1 - 3.9e-59 200.9 0.0 4.7e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM76584.1 - 7e-08 32.6 0.0 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold MsyB PF13984.6 KFM76584.1 - 0.15 12.4 0.0 0.66 10.3 0.0 2.0 2 0 0 2 2 2 0 MsyB protein Asparaginase_II PF06089.12 KFM76587.1 - 0.21 10.6 2.2 0.3 10.1 2.2 1.2 1 0 0 1 1 1 0 L-asparaginase II RNase_H PF00075.24 KFM76588.1 - 4.1e-08 33.5 0.7 2.6e-07 30.9 0.1 2.3 2 1 0 2 2 2 1 RNase H RVT_1 PF00078.27 KFM76589.1 - 1.1e-11 44.7 0.0 1.4e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PaO PF08417.12 KFM76589.1 - 0.009 16.1 0.1 0.014 15.6 0.1 1.5 1 1 0 1 1 1 1 Pheophorbide a oxygenase zf-MYND PF01753.18 KFM76591.1 - 6.4e-07 29.4 7.1 9.6e-07 28.8 7.1 1.3 1 0 0 1 1 1 1 MYND finger GOLGA2L5 PF15070.6 KFM76592.1 - 3e-86 290.5 92.7 2.8e-51 174.9 39.5 4.4 1 1 1 3 3 3 2 Putative golgin subfamily A member 2-like protein 5 APG6_N PF17675.1 KFM76592.1 - 0.019 15.5 18.9 0.019 15.5 18.9 9.8 1 1 5 8 8 8 0 Apg6 coiled-coil region Abi_C PF14355.6 KFM76592.1 - 0.62 10.2 4.6 3.1 8.0 0.3 4.2 3 0 0 3 3 3 0 Abortive infection C-terminus Myosin_tail_1 PF01576.19 KFM76592.1 - 4 5.1 158.3 0.024 12.5 10.8 5.1 1 1 4 5 5 5 0 Myosin tail RTBV_P46 PF06216.11 KFM76592.1 - 4.4 6.1 18.8 1.9 7.3 0.8 3.8 2 1 0 3 3 3 0 Rice tungro bacilliform virus P46 protein Dynamin_N PF00350.23 KFM76593.1 - 0.0054 16.8 0.1 0.0062 16.6 0.1 1.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFM76593.1 - 0.013 15.6 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFM76593.1 - 0.016 15.6 0.0 0.016 15.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFM76593.1 - 0.029 14.9 0.0 0.029 14.9 0.0 1.1 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KFM76593.1 - 0.034 14.0 0.0 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KFM76593.1 - 0.04 13.6 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KFM76593.1 - 0.075 12.1 0.0 0.075 12.1 0.0 1.0 1 0 0 1 1 1 0 Type II/IV secretion system protein AIG1 PF04548.16 KFM76593.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 AIG1 family AAA_28 PF13521.6 KFM76593.1 - 0.12 12.7 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain RHD3 PF05879.12 KFM76593.1 - 0.13 10.4 0.0 0.14 10.2 0.0 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 KFM76594.1 - 1.8e-07 31.4 0.0 2e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 KFM76594.1 - 6.1e-05 22.6 0.0 0.0001 21.9 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM76594.1 - 9.6e-05 22.4 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase DDE_1 PF03184.19 KFM76595.1 - 2.4e-11 43.6 0.2 3.3e-11 43.2 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Na_Ca_ex PF01699.24 KFM76596.1 - 4.4e-49 166.3 37.3 8.2e-25 87.5 15.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Endonuclease_NS PF01223.23 KFM76597.1 - 7.4e-07 29.2 0.0 1.1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF2997 PF11211.8 KFM76597.1 - 0.19 11.6 0.0 0.62 9.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Phosphodiest PF01663.22 KFM76598.1 - 1.7e-05 24.6 0.0 1.8e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Phosphodiest PF01663.22 KFM76599.1 - 3.1e-33 115.9 0.1 4.7e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HTH_Tnp_Tc3_2 PF01498.18 KFM76599.1 - 3.3e-19 68.9 3.4 7.4e-19 67.8 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76599.1 - 8e-16 58.1 0.0 3.3e-15 56.1 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM76599.1 - 4.7e-07 30.3 2.0 4.7e-07 30.3 2.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM76599.1 - 0.00062 19.6 0.6 0.007 16.2 0.0 2.5 1 1 1 2 2 2 1 MarR family HTH_29 PF13551.6 KFM76599.1 - 0.002 18.1 0.3 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 KFM76599.1 - 0.0022 17.9 0.3 0.025 14.5 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KFM76599.1 - 0.0022 18.1 0.8 0.39 10.9 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM76599.1 - 0.04 14.0 0.2 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KFM76599.1 - 0.043 13.6 1.5 1.6 8.7 0.0 2.8 2 1 0 2 2 2 0 Homeodomain-like domain HTH_17 PF12728.7 KFM76599.1 - 0.13 12.5 0.2 26 5.1 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain RNase_H PF00075.24 KFM76600.1 - 1.5e-15 57.6 2.0 3.4e-15 56.5 2.0 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM76600.1 - 1.1e-06 28.4 0.3 1.6e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like DUF1510 PF07423.11 KFM76600.1 - 0.0041 17.2 0.2 0.0087 16.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1510) PAS_3 PF08447.12 KFM76600.1 - 0.15 12.3 0.4 0.47 10.8 0.1 1.9 2 0 0 2 2 2 0 PAS fold Glucosamine_iso PF01182.20 KFM76601.1 - 4.8e-23 82.2 0.0 6.4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DDE_Tnp_1_7 PF13843.6 KFM76602.1 - 2.2e-05 23.9 0.0 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Pkinase_Tyr PF07714.17 KFM76603.1 - 1.8e-97 325.7 0.0 2.7e-97 325.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_3 PF13927.6 KFM76603.1 - 1.1e-42 144.5 8.8 9.2e-09 35.8 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain Pkinase PF00069.25 KFM76603.1 - 1.3e-40 139.5 0.2 1.2e-27 97.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.16 KFM76603.1 - 9.6e-39 131.4 5.9 4.4e-12 45.9 0.0 6.8 6 1 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM76603.1 - 4.2e-20 71.9 16.7 0.00015 22.0 0.0 7.5 7 2 0 7 7 6 4 Immunoglobulin domain ig PF00047.25 KFM76603.1 - 5.3e-19 68.2 16.0 3.5e-05 23.9 0.0 7.5 8 0 0 8 8 8 4 Immunoglobulin domain V-set PF07686.17 KFM76603.1 - 4e-13 49.5 11.9 2.6e-05 24.4 0.3 6.6 6 1 0 6 6 6 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM76603.1 - 8.2e-07 28.5 3.9 2.3 7.8 0.0 5.8 6 0 0 6 6 6 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFM76603.1 - 0.00011 22.2 1.5 2 8.5 0.0 4.9 6 0 0 6 6 5 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFM76603.1 - 0.0036 17.5 0.2 1.8 8.8 0.0 3.4 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Pkinase_fungal PF17667.1 KFM76603.1 - 0.012 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KFM76603.1 - 0.025 13.9 0.0 0.068 12.5 0.0 1.6 2 0 0 2 2 2 0 Kinase-like AP1AR PF15745.5 KFM76605.1 - 0.03 14.0 0.4 0.03 14.0 0.4 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein SPARC_Ca_bdg PF10591.9 KFM76606.1 - 3.2e-38 130.5 3.3 3.2e-38 130.5 3.3 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 KFM76606.1 - 2.4e-05 24.3 11.0 2.7e-05 24.2 8.2 2.7 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.10 KFM76606.1 - 2.9e-05 24.1 8.4 2.9e-05 24.1 8.4 2.9 4 0 0 4 4 4 1 Follistatin/Osteonectin-like EGF domain EF-hand_6 PF13405.6 KFM76606.1 - 0.015 15.1 2.1 1.4 9.1 0.0 3.9 5 0 0 5 5 5 0 EF-hand domain EF-hand_1 PF00036.32 KFM76606.1 - 0.12 12.0 0.8 3.5 7.4 0.0 3.1 3 0 0 3 3 3 0 EF hand FAM176 PF14851.6 KFM76606.1 - 0.26 11.0 3.6 0.24 11.1 0.3 2.2 2 0 0 2 2 2 0 FAM176 family EF-hand_7 PF13499.6 KFM76606.1 - 0.31 11.5 5.2 2.3 8.7 0.5 2.9 2 1 0 2 2 2 0 EF-hand domain pair HTH_Tnp_Tc3_2 PF01498.18 KFM76607.1 - 4.7e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76607.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76607.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76607.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76607.1 - 2.2 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Sec1 PF00995.23 KFM76608.1 - 2.1e-132 443.3 7.9 2.4e-132 443.1 7.9 1.0 1 0 0 1 1 1 1 Sec1 family DUF2489 PF10675.9 KFM76608.1 - 0.034 14.1 0.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Ribosomal_L11_N PF03946.14 KFM76608.1 - 0.08 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain V-ATPase_H_C PF11698.8 KFM76608.1 - 0.61 10.2 2.8 6.8 6.8 0.1 3.5 2 2 0 3 3 3 0 V-ATPase subunit H DUF4518 PF15008.6 KFM76609.1 - 2.4e-66 223.7 0.3 2.7e-66 223.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) Sec7 PF01369.20 KFM76610.1 - 3.3e-76 255.0 0.0 4.3e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KFM76610.1 - 3.5e-27 95.0 0.6 6.4e-27 94.1 0.6 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM76610.1 - 4.1e-08 33.6 0.8 4.1e-08 33.6 0.8 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFM76610.1 - 0.0012 19.1 0.1 0.053 13.8 0.0 2.8 2 1 1 3 3 3 1 Pleckstrin homology domain PH_16 PF17838.1 KFM76610.1 - 0.021 14.6 0.0 0.2 11.5 0.1 2.1 2 0 0 2 2 2 0 PH domain PH_3 PF14593.6 KFM76610.1 - 0.04 14.0 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 PH domain MARVEL PF01284.23 KFM76611.1 - 6.4e-05 23.0 0.1 6.4e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain MARVEL PF01284.23 KFM76612.1 - 1.6e-08 34.7 4.7 1.9e-08 34.5 4.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain Chitin_bind_4 PF00379.23 KFM76613.1 - 3.8e-10 40.1 6.1 3.8e-10 40.1 6.1 1.9 2 0 0 2 2 2 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM76614.1 - 5.2e-13 49.3 4.3 9.5e-13 48.5 4.3 1.5 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM76615.1 - 5.3e-11 42.9 4.3 9.6e-11 42.1 4.3 1.5 1 0 0 1 1 1 1 Insect cuticle protein Arm PF00514.23 KFM76616.1 - 8.9e-55 181.2 5.7 3.7e-13 49.0 0.1 6.3 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFM76616.1 - 1.9e-23 82.7 6.5 3.8e-23 81.7 6.5 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.22 KFM76616.1 - 1.3e-17 62.4 1.0 0.0014 18.7 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 KFM76616.1 - 4e-16 59.1 1.5 4.2e-07 30.3 0.1 4.3 3 2 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KFM76616.1 - 2.4e-15 56.7 0.0 3.9e-07 30.4 0.0 4.3 2 2 3 5 5 5 3 HEAT repeats Adaptin_N PF01602.20 KFM76616.1 - 4.8e-05 22.1 0.1 0.00014 20.6 0.1 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd3 PF12719.7 KFM76616.1 - 0.0023 17.2 0.1 0.5 9.5 0.0 3.3 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Atx10homo_assoc PF09759.9 KFM76616.1 - 0.0055 16.7 0.0 4.7 7.3 0.0 3.8 2 2 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 KFM76616.1 - 0.028 13.9 0.1 1.9 7.9 0.0 2.4 2 1 0 2 2 2 0 Armadillo-like HEAT_PBS PF03130.16 KFM76616.1 - 0.037 14.7 0.1 1.1e+02 3.9 0.0 4.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 KFM76616.1 - 0.074 13.2 0.0 10 6.3 0.0 3.0 3 0 0 3 3 3 0 V-ATPase subunit H Tecti-min-caps PF09300.10 KFM76616.1 - 0.18 11.9 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Tectiviridae, minor capsid DnaJ_C PF01556.18 KFM76618.1 - 2.4e-42 144.5 0.4 3.6e-42 144.0 0.4 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFM76618.1 - 1.1e-26 92.7 0.8 1.9e-26 91.9 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFM76618.1 - 5e-16 58.8 19.6 8.8e-16 58.0 19.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KFM76618.1 - 0.019 15.0 6.1 1.6 8.8 0.4 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KFM76618.1 - 0.039 13.9 12.1 0.64 10.0 0.3 3.0 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Tubulin-binding PF00418.19 KFM76620.1 - 2.3e-12 46.7 6.2 2.9e-08 33.6 0.2 3.0 3 0 0 3 3 3 2 Tau and MAP protein, tubulin-binding repeat HTH_Tnp_Tc3_2 PF01498.18 KFM76621.1 - 2.5e-16 59.7 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76621.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Fringe PF02434.16 KFM76622.1 - 1.5e-13 50.8 0.2 9.9e-13 48.1 0.2 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KFM76622.1 - 7.1e-06 26.0 0.0 0.0051 16.6 0.1 2.3 1 1 1 2 2 2 2 Galactosyltransferase CarbpepA_inh PF02977.15 KFM76623.1 - 0.065 13.0 7.2 0.84 9.5 4.8 2.6 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor dCache_1 PF02743.18 KFM76624.1 - 3.3e-24 86.0 0.8 3.9e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Cache domain Delta_lysin PF05372.11 KFM76624.1 - 0.013 14.8 0.3 0.027 13.8 0.3 1.5 1 0 0 1 1 1 0 Delta lysin family VGCC_alpha2 PF08473.11 KFM76624.1 - 0.16 10.8 0.9 2 7.1 0.3 2.5 1 1 1 2 2 2 0 Neuronal voltage-dependent calcium channel alpha 2acd Herpes_US12 PF05363.12 KFM76625.1 - 0.11 13.2 0.0 0.12 13.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus US12 family VWA_N PF08399.11 KFM76626.1 - 6.3e-05 23.5 0.0 0.00015 22.3 0.0 1.6 1 0 0 1 1 1 1 VWA N-terminal Ribosomal_L5e PF17144.4 KFM76626.1 - 0.02 14.9 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 HU-CCDC81_bac_1 PF18174.1 KFM76626.1 - 0.03 14.2 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 1 RPOL_N PF14700.6 KFM76627.1 - 0.0049 16.3 0.9 0.0062 16.0 0.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF2326 PF10088.9 KFM76627.1 - 0.042 13.6 3.6 0.18 11.6 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) Arabinose_Isome PF02610.15 KFM76627.1 - 0.077 12.2 3.2 0.067 12.4 0.7 1.8 2 0 0 2 2 2 0 L-arabinose isomerase DDE_3 PF13358.6 KFM76628.1 - 1.1e-07 31.7 0.0 1.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease RasGAP PF00616.19 KFM76628.1 - 0.047 13.4 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase 7tm_1 PF00001.21 KFM76629.1 - 2.1e-05 24.0 0.5 2.1e-05 24.0 0.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HTH_Tnp_Tc3_2 PF01498.18 KFM76630.1 - 2.1e-16 59.9 2.7 4.8e-16 58.8 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76630.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ubiquitin PF00240.23 KFM76634.1 - 4e-19 68.1 1.8 3.7e-18 65.1 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin family zf-AN1 PF01428.16 KFM76634.1 - 1.7e-09 37.6 8.7 4e-09 36.5 8.7 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 KFM76634.1 - 1.2e-05 25.1 0.4 0.00014 21.7 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFM76634.1 - 0.0027 18.1 0.0 0.012 16.1 0.0 2.2 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_4 PF12799.7 KFM76635.1 - 1.8e-07 31.3 12.7 0.33 11.4 0.2 5.2 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM76635.1 - 2.6e-07 30.2 13.5 0.61 10.3 0.0 7.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KFM76635.1 - 2.2e-05 24.4 16.1 13 6.8 0.0 7.0 7 0 0 7 7 7 3 Leucine Rich Repeat F-box PF00646.33 KFM76635.1 - 0.24 11.3 0.1 0.24 11.3 0.1 3.6 5 0 0 5 5 5 0 F-box domain F-box-like PF12937.7 KFM76635.1 - 2.3 8.2 5.3 1.6 8.7 0.1 3.3 4 0 0 4 4 4 0 F-box-like TGF_beta PF00019.20 KFM76636.1 - 5.4e-31 107.7 1.2 8.6e-31 107.0 0.2 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFM76636.1 - 0.00047 20.0 0.9 0.0044 16.8 0.1 2.3 1 1 1 2 2 2 1 TGF-beta propeptide HTH_Tnp_Tc3_2 PF01498.18 KFM76637.1 - 3.9e-16 59.0 3.0 6.3e-16 58.4 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76637.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76637.1 - 3.2e-07 30.0 1.6 7.6e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76637.1 - 0.0029 17.3 0.6 0.0082 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76637.1 - 2.9 8.6 15.6 0.14 12.8 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-C2H2 PF00096.26 KFM76638.1 - 1.2e-07 31.8 17.9 0.00086 19.6 7.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76638.1 - 8.8e-07 29.2 14.4 0.0057 17.4 1.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM76638.1 - 0.00061 19.7 14.8 0.005 16.8 2.0 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM76638.1 - 0.0023 18.2 11.1 0.073 13.4 3.1 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM76638.1 - 0.0099 16.3 2.3 0.0099 16.3 2.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM76638.1 - 0.079 13.3 10.0 0.14 12.4 1.8 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 KFM76638.1 - 0.08 13.0 2.1 0.42 10.7 0.1 2.0 1 1 0 2 2 2 0 CpXC protein PriA_CRR PF18319.1 KFM76638.1 - 0.12 12.4 0.2 0.12 12.4 0.2 3.2 4 0 0 4 4 4 0 PriA DNA helicase Cys-rich region (CRR) domain zinc_ribbon_4 PF13717.6 KFM76638.1 - 0.13 12.2 2.0 6.9 6.7 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.15 KFM76638.1 - 0.15 12.1 9.9 0.93 9.6 2.1 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_9 PF16293.5 KFM76638.1 - 0.17 11.7 4.1 2.8 7.9 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM76638.1 - 2.6 8.2 8.6 11 6.3 1.8 2.1 2 0 0 2 2 2 0 FYVE zinc finger zf_ZIC PF18366.1 KFM76638.1 - 7 6.8 9.1 36 4.6 5.5 2.2 1 1 1 2 2 2 0 Zic proteins zinc finger domain zf-C2HE PF16278.5 KFM76638.1 - 7.7 7.0 9.4 2 8.9 6.3 1.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Tugs PF17840.1 KFM76639.1 - 0.019 15.1 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain DNA_pol_A PF00476.20 KFM76641.1 - 6.1e-23 81.5 0.0 6.9e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family A HlyD_D23 PF16576.5 KFM76643.1 - 0.82 8.8 10.2 0.84 8.8 8.0 2.1 2 1 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Sterile PF03015.19 KFM76643.1 - 1.3 9.3 5.5 1.7 8.9 0.4 3.1 3 0 0 3 3 3 0 Male sterility protein FAM184 PF15665.5 KFM76643.1 - 1.8 8.3 37.0 0.64 9.8 30.2 3.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Pox_A_type_inc PF04508.12 KFM76643.1 - 3.2 7.7 11.7 20 5.3 0.3 5.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF3929 PF13066.6 KFM76645.1 - 0.56 10.3 2.6 20 5.3 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3929) Kinesin PF00225.23 KFM76646.1 - 7.5e-45 153.3 3.1 8.1e-45 153.2 3.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain DDE_3 PF13358.6 KFM76647.1 - 5.9e-17 61.8 0.0 1.7e-14 53.8 0.0 3.1 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76647.1 - 9.8e-17 61.0 6.3 5.8e-10 39.3 1.0 2.4 2 0 0 2 2 2 2 Transposase Kinesin PF00225.23 KFM76647.1 - 0.072 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain SNAP PF14938.6 KFM76649.1 - 1.9e-112 375.3 21.3 2.2e-112 375.1 21.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KFM76649.1 - 3.5e-12 46.4 12.5 7.9e-06 26.1 2.1 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM76649.1 - 8e-08 31.9 16.2 0.035 14.3 0.7 6.0 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM76649.1 - 1.4e-07 31.0 10.9 0.0015 18.5 0.3 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM76649.1 - 1.4e-05 25.4 13.4 1.1 10.1 0.1 5.2 5 2 2 7 7 5 3 Tetratricopeptide repeat NSF PF02071.20 KFM76649.1 - 4.1e-05 23.5 40.7 0.1 13.4 1.9 8.4 7 2 2 9 9 9 2 Aromatic-di-Alanine (AdAR) repeat TPR_MalT PF17874.1 KFM76649.1 - 5e-05 22.8 6.0 0.0058 16.1 6.0 2.2 1 1 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 KFM76649.1 - 8.3e-05 22.4 22.4 0.058 13.5 0.2 5.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM76649.1 - 0.00039 21.0 5.2 0.019 15.6 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KFM76649.1 - 0.0029 17.3 3.7 0.005 16.5 3.7 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_1 PF00515.28 KFM76649.1 - 0.014 15.2 21.4 0.2 11.5 1.0 5.3 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM76649.1 - 0.022 15.0 2.9 0.022 15.0 2.9 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KFM76649.1 - 0.037 14.4 0.4 2.7 8.4 0.0 3.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KFM76649.1 - 0.094 12.6 9.8 2.8 7.9 0.1 5.0 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM76649.1 - 0.098 13.5 6.6 6.1 7.9 0.0 4.9 2 2 3 6 6 5 0 Tetratricopeptide repeat Sel1 PF08238.12 KFM76649.1 - 0.25 12.1 3.7 4.4 8.1 0.1 4.1 4 0 0 4 4 4 0 Sel1 repeat TPR_19 PF14559.6 KFM76649.1 - 0.65 10.5 9.9 0.67 10.5 1.1 3.9 1 1 1 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KFM76649.1 - 1.6 8.4 12.7 13 5.5 4.0 3.2 1 1 3 4 4 4 0 26S proteasome subunit RPN7 TPR_3 PF07720.12 KFM76649.1 - 2.3 8.3 12.8 5.7 7.0 1.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM76649.1 - 3.2 7.5 18.8 1.3 8.8 1.2 4.6 4 1 0 4 4 4 0 TPR repeat MIT PF04212.18 KFM76649.1 - 4.8 7.3 28.8 3.7 7.7 1.2 6.2 3 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 KFM76649.1 - 5.4 7.3 13.0 12 6.2 0.2 4.7 1 1 3 4 4 4 0 MIT domain of nuclear receptor-binding factor 2 Yip1 PF04893.17 KFM76650.1 - 1.4e-15 57.4 14.6 1.4e-15 57.4 14.6 2.0 1 1 1 2 2 2 1 Yip1 domain DUF4386 PF14329.6 KFM76650.1 - 0.00029 20.8 0.6 0.00029 20.8 0.6 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4386) CstA_5TM PF13722.6 KFM76650.1 - 0.28 11.6 7.8 0.86 10.0 7.8 2.0 1 1 0 1 1 1 0 5TM C-terminal transporter carbon starvation CstA Tetraspanin PF00335.20 KFM76650.1 - 0.39 10.4 5.4 0.14 11.9 1.9 1.9 1 1 1 2 2 2 0 Tetraspanin family SLATT_4 PF18186.1 KFM76650.1 - 4.8 6.8 7.3 4.1 7.0 1.6 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 AcetylCoA_hyd_C PF13336.6 KFM76651.1 - 3.4e-50 170.0 0.1 5.8e-50 169.2 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KFM76651.1 - 7.6e-24 84.8 0.0 1.4e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DeoRC PF00455.22 KFM76651.1 - 0.055 13.4 0.0 5.1 7.0 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain p53-inducible11 PF14936.6 KFM76652.1 - 3.5e-35 121.7 0.1 5.8e-35 121.0 0.1 1.3 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 CBM53 PF16760.5 KFM76652.1 - 0.066 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Phage_Gp23 PF10669.9 KFM76653.1 - 0.59 10.5 0.1 0.59 10.5 0.1 1.9 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) DCR PF14047.6 KFM76654.1 - 0.036 14.3 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region An_peroxidase PF03098.15 KFM76656.1 - 2.6e-162 541.1 0.1 3.5e-162 540.7 0.1 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Proteasome PF00227.26 KFM76657.1 - 6.1e-44 149.8 0.2 6.8e-44 149.6 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Glyco_transf_8 PF01501.20 KFM76658.1 - 6.9e-06 25.8 0.3 1.4e-05 24.8 0.3 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 GpcrRhopsn4 PF10192.9 KFM76660.1 - 4.5e-13 49.2 4.6 5.5e-13 48.9 4.6 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Dynein_IC2 PF11540.8 KFM76661.1 - 1.3e-08 34.6 3.6 1.3e-08 34.6 3.6 2.0 2 0 0 2 2 2 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 KFM76662.1 - 4.8e-10 39.9 17.2 0.29 12.1 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM76662.1 - 0.024 14.9 0.5 1.3 9.4 0.1 3.7 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KFM76662.1 - 0.06 12.7 0.1 4.3 6.6 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cas_Cas02710 PF09670.10 KFM76662.1 - 0.21 10.4 0.1 0.32 9.8 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Ubiquitin_3 PF14836.6 KFM76663.1 - 0.062 13.3 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain AAA_lid_7 PF17867.1 KFM76664.1 - 0.0047 17.1 0.0 0.0069 16.6 0.0 1.3 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_5 PF07728.14 KFM76664.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KFM76665.1 - 7.7e-09 35.7 0.0 9.3e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_lid_5 PF17865.1 KFM76667.1 - 2.2e-08 34.1 0.0 2.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_lid_7 PF17867.1 KFM76668.1 - 4.4e-12 46.1 0.0 7.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_5 PF07728.14 KFM76668.1 - 5.3e-10 39.4 0.0 7.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFM76668.1 - 0.00081 19.3 0.0 0.0018 18.2 0.0 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 KFM76668.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KFM76669.1 - 5.3e-25 88.0 0.0 7.4e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KFM76669.1 - 3.3e-06 26.7 0.0 2.7e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 KFM76669.1 - 0.00037 20.9 0.0 0.00069 20.0 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 KFM76669.1 - 0.00042 19.4 0.0 1 8.2 0.0 2.6 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KFM76669.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFM76669.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFM76669.1 - 0.0068 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KFM76669.1 - 0.013 15.2 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KFM76669.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KFM76669.1 - 0.019 15.3 0.0 0.034 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 KFM76669.1 - 0.024 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 KFM76669.1 - 0.03 14.1 0.0 0.074 12.8 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFM76669.1 - 0.055 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFM76669.1 - 0.056 13.4 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KFM76669.1 - 0.07 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_8 PF12780.7 KFM76669.1 - 0.089 12.1 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region D4 MCM PF00493.23 KFM76669.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain ATPase PF06745.13 KFM76669.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_lid_7 PF17867.1 KFM76670.1 - 7.9e-14 51.7 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_5 PF07728.14 KFM76670.1 - 1.8e-07 31.2 0.0 3.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KFM76670.1 - 1.9e-05 24.7 0.1 2.9e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KFM76670.1 - 3.2e-05 24.5 0.0 7.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KFM76670.1 - 0.00037 20.9 0.0 0.00057 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_6 PF12774.7 KFM76670.1 - 0.00056 19.0 0.1 0.0022 17.0 0.0 2.0 2 1 1 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 KFM76670.1 - 0.0006 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KFM76670.1 - 0.0008 20.0 0.4 0.0022 18.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFM76670.1 - 0.00084 19.5 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM76670.1 - 0.00099 19.4 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KFM76670.1 - 0.0033 17.3 0.1 0.0057 16.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KFM76670.1 - 0.0055 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KFM76670.1 - 0.0076 16.7 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_8 PF12780.7 KFM76670.1 - 0.0083 15.5 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_25 PF13481.6 KFM76670.1 - 0.0085 15.7 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM76670.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFM76670.1 - 0.014 14.9 0.1 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KFM76670.1 - 0.024 13.8 0.1 0.053 12.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KFM76670.1 - 0.031 13.5 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 KFM76670.1 - 0.032 13.3 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 KFM76670.1 - 0.037 13.8 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase ATP_bind_1 PF03029.17 KFM76670.1 - 0.039 13.7 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KFM76670.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KFM76670.1 - 0.045 14.2 0.0 0.071 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM76670.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM76670.1 - 0.062 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KFM76670.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFM76670.1 - 0.065 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KFM76670.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFM76670.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase 7tm_1 PF00001.21 KFM76671.1 - 0.00074 18.9 0.0 0.00085 18.7 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Nuc_N PF14448.6 KFM76671.1 - 0.044 13.6 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 Nuclease N terminal MarR_2 PF12802.7 KFM76671.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 MarR family AAA_5 PF07728.14 KFM76673.1 - 1e-11 45.0 0.0 1.1e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KFM76673.1 - 4.7e-05 23.5 0.0 5.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain VWA_2 PF13519.6 KFM76679.1 - 9.7e-08 32.6 0.5 4.8e-07 30.4 0.5 2.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFM76679.1 - 1.1e-06 29.0 0.7 1.1e-06 29.0 0.7 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain NDUFV3 PF15880.5 KFM76680.1 - 9.4e-12 44.7 0.5 1.3e-11 44.2 0.5 1.3 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial PCNP PF15473.6 KFM76681.1 - 2.9e-41 141.8 9.2 3.9e-41 141.4 9.2 1.2 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family SAM_2 PF07647.17 KFM76682.1 - 4.7e-19 68.2 1.1 5.7e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM76682.1 - 7.6e-18 64.7 0.7 9.8e-08 32.3 0.0 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Pkinase PF00069.25 KFM76686.1 - 6.5e-62 209.3 3.3 9.1e-62 208.8 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM76686.1 - 6.1e-32 110.9 1.0 1.6e-22 80.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFM76686.1 - 4e-05 24.2 0.4 0.00017 22.2 0.3 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFM76686.1 - 7.8e-05 21.8 0.5 0.00013 21.1 0.5 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM76686.1 - 9.1e-05 21.9 0.2 0.00024 20.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM76686.1 - 0.00013 21.3 0.1 0.012 15.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KFM76686.1 - 0.0011 19.0 1.0 0.028 14.3 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 KFM76687.1 - 2.4e-45 155.0 0.0 3.2e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM76687.1 - 1e-27 97.1 0.0 1.4e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM76687.1 - 1.1e-07 31.5 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM76687.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFM76687.1 - 0.2 11.6 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KFM76688.1 - 1.7e-13 50.5 0.0 2.1e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM76688.1 - 5.6e-05 22.5 0.1 6.7e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DDT PF02791.17 KFM76691.1 - 4.1e-16 59.0 1.4 4.1e-16 59.0 1.4 1.9 2 0 0 2 2 2 1 DDT domain PHD PF00628.29 KFM76691.1 - 5.1e-09 35.9 10.3 1.2e-08 34.7 10.3 1.6 1 0 0 1 1 1 1 PHD-finger WSD PF15613.6 KFM76691.1 - 1.6e-07 31.7 1.8 3.5e-05 24.2 1.8 2.8 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 KFM76691.1 - 0.0029 17.1 0.0 0.0082 15.7 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD PF00628.29 KFM76694.1 - 1.3e-10 41.0 7.6 2.8e-10 39.9 7.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFM76694.1 - 0.052 13.1 2.8 0.1 12.2 2.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KFM76694.1 - 0.74 10.2 5.6 1.8 9.0 5.6 1.6 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.29 KFM76695.1 - 8.8e-09 35.1 6.5 1.2e-08 34.7 6.5 1.2 1 0 0 1 1 1 1 PHD-finger Zn-ribbon_8 PF09723.10 KFM76695.1 - 0.039 14.1 2.9 0.059 13.5 2.9 1.3 1 0 0 1 1 1 0 Zinc ribbon domain PHD_2 PF13831.6 KFM76695.1 - 0.2 11.3 7.2 0.3 10.7 7.2 1.3 1 0 0 1 1 1 0 PHD-finger zf-FPG_IleRS PF06827.14 KFM76695.1 - 0.47 10.4 0.2 0.47 10.4 0.2 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS RRM_1 PF00076.22 KFM76696.1 - 1.6e-05 24.6 0.4 3.6e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dmrt1 PF12374.8 KFM76696.1 - 0.087 13.3 0.8 0.087 13.3 0.8 3.3 4 0 0 4 4 4 0 Double-sex mab3 related transcription factor 1 B9-C2 PF07162.11 KFM76697.1 - 2.2e-51 174.4 0.0 2.5e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Otopetrin PF03189.13 KFM76698.1 - 1.5e-93 314.1 20.5 1.8e-92 310.5 20.4 1.9 1 1 0 1 1 1 1 Otopetrin EGF_3 PF12947.7 KFM76698.1 - 0.2 11.9 1.3 0.48 10.7 1.3 1.6 1 0 0 1 1 1 0 EGF domain An_peroxidase PF03098.15 KFM76700.1 - 9.3e-33 113.6 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase RVT_1 PF00078.27 KFM76701.1 - 3.4e-37 128.1 0.0 6.6e-37 127.2 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CTNNBL PF08216.11 KFM76702.1 - 8.4e-36 122.3 0.2 4e-35 120.1 0.2 2.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KFM76702.1 - 0.026 14.6 0.4 8.7 6.5 0.1 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CutA1 PF03091.15 KFM76703.1 - 0.053 13.4 2.0 0.099 12.5 2.0 1.5 1 1 0 1 1 1 0 CutA1 divalent ion tolerance protein p450 PF00067.22 KFM76704.1 - 5.5e-76 256.2 0.0 6.4e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M13_N PF05649.13 KFM76706.1 - 2.3e-22 80.2 0.5 2.5e-22 80.1 0.5 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM76707.1 - 1.6e-12 47.5 0.0 1.6e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Adeno_E3_CR2 PF02439.15 KFM76708.1 - 0.065 13.0 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4636 PF15468.6 KFM76708.1 - 0.083 12.6 0.2 0.096 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) CDP-OH_P_transf PF01066.21 KFM76710.1 - 1.9e-13 50.9 0.6 1.9e-13 50.9 0.6 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ldl_recept_a PF00057.18 KFM76711.1 - 5.4e-11 42.5 6.8 5.4e-11 42.5 6.8 3.0 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A CBM_14 PF01607.24 KFM76711.1 - 1.3e-10 41.3 2.0 1.3e-10 41.3 2.0 2.7 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Polysacc_deac_1 PF01522.21 KFM76711.1 - 1e-09 38.4 0.3 4.5e-09 36.2 0.3 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF2315 PF10231.9 KFM76711.1 - 0.035 14.2 0.6 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Apoptogenic protein 1 SAM_PNT PF02198.16 KFM76711.1 - 0.07 13.1 0.4 9.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain HTH_Tnp_Tc3_2 PF01498.18 KFM76712.1 - 3.3e-16 59.3 3.3 5e-16 58.7 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76712.1 - 1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76712.1 - 5.7e-08 32.4 2.1 1.3e-07 31.3 0.4 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76712.1 - 0.0036 17.1 1.1 0.01 15.6 1.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76712.1 - 0.0069 16.5 0.8 0.021 14.9 0.8 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 KFM76712.1 - 1.4 9.6 17.4 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM76716.1 - 4.1e-16 59.0 3.4 5.3e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76716.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76716.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76716.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76716.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM76717.1 - 4.2e-16 59.0 0.1 3.3e-15 56.1 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76717.1 - 2.9e-10 40.3 1.0 2.9e-10 40.3 1.0 1.9 2 0 0 2 2 2 1 Transposase Peptidase_M13_N PF05649.13 KFM76718.1 - 9.7e-89 298.7 1.8 9.7e-89 298.7 1.8 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM76718.1 - 2.9e-70 236.1 0.2 5.4e-70 235.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M13 CSN8_PSD8_EIF3K PF10075.9 KFM76719.1 - 9.6e-28 97.0 0.1 1.7e-27 96.2 0.1 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Ank_2 PF12796.7 KFM76720.1 - 4.9e-39 132.8 9.1 1.2e-13 51.4 0.5 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM76720.1 - 6.9e-36 122.2 11.2 4.4e-10 39.9 0.1 6.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFM76720.1 - 6.2e-34 115.0 13.3 1.2e-05 25.5 0.1 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 KFM76720.1 - 1.1e-25 86.8 9.7 0.0016 18.8 0.0 8.7 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 KFM76720.1 - 1.8e-22 79.1 8.7 2.3e-05 24.6 0.0 6.8 3 2 5 8 8 8 7 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFM76720.1 - 0.00029 21.1 2.7 0.0011 19.2 2.7 2.1 1 0 0 1 1 1 1 SOCS box DCB PF16213.5 KFM76720.1 - 0.017 14.8 1.2 0.26 10.9 0.2 2.3 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 WD40 PF00400.32 KFM76721.1 - 2e-34 117.1 9.1 2.5e-08 34.4 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM76721.1 - 3.6e-09 36.8 0.1 0.076 13.3 0.0 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM76721.1 - 0.00015 21.2 0.0 0.13 11.5 0.0 2.9 1 1 2 3 3 3 3 WD40-like domain Nup160 PF11715.8 KFM76721.1 - 0.00023 19.9 0.8 0.13 10.9 0.1 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFM76721.1 - 0.001 18.1 0.6 5.4 5.9 0.1 3.5 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KFM76721.1 - 0.029 13.5 0.0 0.075 12.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) Big_7 PF17957.1 KFM76721.1 - 0.25 12.1 1.1 0.61 10.9 0.1 2.1 2 1 1 3 3 3 0 Bacterial Ig domain FHA PF00498.26 KFM76722.1 - 1.8e-13 50.6 0.0 4.5e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM76722.1 - 0.1 12.9 0.0 2.4 8.5 0.0 2.6 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Malic_M PF03949.15 KFM76723.1 - 1.1e-98 329.7 0.1 1.4e-98 329.3 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFM76723.1 - 7.9e-79 263.7 0.0 1.2e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Zona_pellucida PF00100.23 KFM76724.1 - 9.4e-17 61.7 0.2 1.5e-16 61.0 0.2 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain EB_dh PF09459.10 KFM76724.1 - 0.065 13.2 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Ethylbenzene dehydrogenase Glyco_transf_8 PF01501.20 KFM76725.1 - 1.5e-24 87.0 2.7 1.9e-22 80.1 2.7 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KFM76725.1 - 0.00088 18.7 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 KFM76725.1 - 0.0032 17.5 0.1 0.0071 16.3 0.1 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase WD40 PF00400.32 KFM76726.1 - 5e-25 87.3 9.5 1.6e-08 35.0 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat FYVE PF01363.21 KFM76726.1 - 3.4e-15 55.9 6.1 3.4e-15 55.9 6.1 1.8 2 0 0 2 2 2 1 FYVE zinc finger Nucleoporin_N PF08801.11 KFM76726.1 - 1.9e-05 23.6 0.8 1.1 7.9 0.1 3.7 3 1 1 4 4 4 3 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KFM76726.1 - 0.00025 21.3 0.6 4.2 7.7 0.0 4.2 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain FYVE_2 PF02318.16 KFM76726.1 - 0.054 13.7 3.8 0.17 12.1 3.8 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger Frtz PF11768.8 KFM76726.1 - 0.084 11.2 0.0 9.2 4.4 0.0 2.8 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2321 PF10083.9 KFM76726.1 - 0.41 10.3 9.5 2.7 7.6 0.5 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Na_K-ATPase PF00287.18 KFM76727.1 - 6.7e-17 61.6 0.4 9.1e-17 61.1 0.4 1.1 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain EF-hand_1 PF00036.32 KFM76728.1 - 0.00065 19.1 0.1 0.0014 18.0 0.0 1.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFM76728.1 - 0.037 13.9 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Na_K-ATPase PF00287.18 KFM76729.1 - 1.9e-83 279.9 1.8 2.3e-83 279.7 1.8 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain HTH_Tnp_Tc3_2 PF01498.18 KFM76730.1 - 3.5e-16 59.2 0.4 6.4e-16 58.4 0.4 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76730.1 - 8.2e-06 26.4 5.5 2.9e-05 24.6 2.3 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Autophagy_N PF03986.13 KFM76731.1 - 5.2e-48 162.5 1.6 5.2e-48 162.5 1.6 1.8 1 1 1 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KFM76731.1 - 1.5e-21 76.7 1.2 4.4e-21 75.2 0.5 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KFM76731.1 - 8.4e-08 31.6 2.7 8.4e-08 31.6 2.7 2.3 3 0 0 3 3 3 1 Autophagocytosis associated protein C-terminal SDA1 PF05285.12 KFM76731.1 - 1 8.7 12.8 0.25 10.7 9.7 1.5 2 0 0 2 2 2 0 SDA1 HLH PF00010.26 KFM76732.1 - 8.8e-15 54.4 0.4 2.3e-14 53.1 0.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM76733.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76733.1 - 7.6e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM76734.1 - 2.1e-16 60.0 0.2 6e-15 55.3 0.0 2.8 1 1 2 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76734.1 - 7.4e-16 58.2 6.5 1.5e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76734.1 - 0.00073 20.1 1.5 0.00073 20.1 1.5 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76734.1 - 0.0025 17.6 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76734.1 - 0.015 15.4 0.1 0.065 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 KFM76734.1 - 0.025 14.6 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM76734.1 - 0.035 14.1 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DEP PF00610.21 KFM76735.1 - 0.00033 20.7 0.0 0.00078 19.4 0.0 1.6 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDDEXK_3 PF13366.6 KFM76737.1 - 0.095 13.1 0.2 0.1 13.0 0.2 1.0 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily HTH_30 PF13556.6 KFM76738.1 - 0.057 13.2 0.0 7.5 6.4 0.0 2.9 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain SelR PF01641.18 KFM76739.1 - 9.8e-51 170.9 1.1 1.2e-50 170.6 1.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 KFM76739.1 - 0.011 15.9 1.6 0.022 14.9 1.6 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TackOD1 PF18551.1 KFM76739.1 - 0.027 14.1 0.3 0.027 14.1 0.3 2.0 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 HECT_2 PF09814.9 KFM76739.1 - 0.07 12.0 1.7 0.17 10.7 0.1 1.9 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zinc_ribbon_10 PF10058.9 KFM76739.1 - 0.085 12.6 2.8 0.62 9.8 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein phage_tail_N PF08400.10 KFM76739.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Prophage tail fibre N-terminal zf-LITAF-like PF10601.9 KFM76739.1 - 0.61 10.4 4.8 0.41 10.9 0.4 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DZR PF12773.7 KFM76739.1 - 2.1 8.5 7.5 12 6.0 0.4 2.7 2 2 0 2 2 2 0 Double zinc ribbon Chitin_bind_4 PF00379.23 KFM76742.1 - 3.7e-07 30.6 0.1 7.3e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Insect cuticle protein HTH_Tnp_Tc3_2 PF01498.18 KFM76744.1 - 2e-16 60.0 2.2 3.9e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76744.1 - 7.8e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Myosin_head PF00063.21 KFM76745.1 - 2.3e-260 865.6 0.2 2.3e-260 865.6 0.2 3.9 4 0 0 4 4 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFM76745.1 - 5e-180 600.8 280.6 6.7e-180 600.4 280.6 1.1 1 0 0 1 1 1 1 Myosin tail DUF1664 PF07889.12 KFM76745.1 - 2.4e-05 24.4 146.1 0.018 15.1 2.9 13.8 3 3 9 13 13 13 8 Protein of unknown function (DUF1664) DUF4795 PF16043.5 KFM76745.1 - 0.00068 19.3 32.9 0.00068 19.3 32.9 9.3 2 2 6 8 8 4 3 Domain of unknown function (DUF4795) DUF3584 PF12128.8 KFM76745.1 - 0.00082 17.0 51.2 0.00082 17.0 51.2 4.5 1 1 3 4 4 3 1 Protein of unknown function (DUF3584) ATG16 PF08614.11 KFM76745.1 - 0.00083 19.6 18.2 0.00083 19.6 18.2 11.6 2 1 11 13 13 12 3 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFM76745.1 - 0.0026 16.7 21.6 0.0026 16.7 21.6 10.3 1 1 11 12 12 11 4 Spc7 kinetochore protein DUF745 PF05335.13 KFM76745.1 - 0.004 16.9 19.4 0.004 16.9 19.4 11.0 2 1 8 11 11 9 3 Protein of unknown function (DUF745) HALZ PF02183.18 KFM76745.1 - 0.0045 17.2 1.4 0.0045 17.2 1.4 14.9 15 4 3 18 18 15 2 Homeobox associated leucine zipper Filament PF00038.21 KFM76745.1 - 0.33 10.5 240.3 0.038 13.6 17.7 8.9 1 1 4 5 5 4 0 Intermediate filament protein DUF812 PF05667.11 KFM76745.1 - 3 6.6 238.7 0.0041 16.1 35.4 8.2 1 1 6 8 8 8 0 Protein of unknown function (DUF812) Oxidored-like PF09791.9 KFM76746.1 - 3.4e-07 29.8 1.4 5.4e-07 29.2 1.4 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal ParA PF10609.9 KFM76747.1 - 9e-78 261.1 0.0 1e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DDE_Tnp_1_7 PF13843.6 KFM76748.1 - 8.2e-14 51.7 0.5 1.4e-13 50.9 0.3 1.4 2 0 0 2 2 2 1 Transposase IS4 OrfA PF17495.2 KFM76749.1 - 0.024 14.8 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 Vpr-like OrfA Tektin PF03148.14 KFM76750.1 - 0.00015 20.6 3.6 0.00018 20.4 3.6 1.1 1 0 0 1 1 1 1 Tektin family BAR_3 PF16746.5 KFM76750.1 - 0.0073 16.0 0.2 0.0096 15.7 0.2 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Tektin PF03148.14 KFM76751.1 - 4e-20 71.9 9.3 4.7e-20 71.7 9.3 1.0 1 0 0 1 1 1 1 Tektin family partial_CstF PF15861.5 KFM76751.1 - 0.018 14.8 0.9 0.046 13.5 0.9 1.7 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain TMF_DNA_bd PF12329.8 KFM76751.1 - 0.042 13.8 0.3 0.042 13.8 0.3 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 KFM76751.1 - 0.063 13.5 10.4 0.46 10.7 3.1 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 KFM76751.1 - 0.18 12.2 6.6 0.69 10.3 0.1 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1043 PF06295.12 KFM76751.1 - 0.26 11.3 3.8 1.8 8.6 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Exonuc_VII_L PF02601.15 KFM76751.1 - 0.96 8.9 6.4 1.2 8.6 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 KFM76751.1 - 1.2 9.3 9.6 9.4 6.5 0.2 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KFM76751.1 - 1.4 9.0 4.3 2.5 8.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.18 KFM76751.1 - 3 7.1 5.8 7.2 5.8 5.8 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.6 KFM76751.1 - 6.5 7.3 10.7 3 8.3 3.3 2.5 2 1 0 2 2 2 0 Snapin/Pallidin Exo_endo_phos_2 PF14529.6 KFM76752.1 - 8e-22 77.3 0.1 1.2e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM76752.1 - 0.00016 21.3 0.1 0.00023 20.8 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FHA PF00498.26 KFM76753.1 - 1.1e-19 70.6 0.3 1e-18 67.4 0.0 2.7 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 KFM76753.1 - 6.9e-09 35.9 0.0 9.4e-07 29.1 0.0 3.2 2 1 1 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain Dicer_dimer PF03368.14 KFM76753.1 - 7.8e-06 26.0 0.1 4.6e-05 23.5 0.0 2.3 3 0 0 3 3 3 1 Dicer dimerisation domain dsrm PF00035.26 KFM76753.1 - 0.00021 21.9 0.1 0.0015 19.2 0.0 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif Osmo_CC PF08946.10 KFM76753.1 - 0.053 13.8 0.8 0.16 12.2 0.8 1.9 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF953 PF06110.11 KFM76754.1 - 8.4e-42 141.5 0.0 9.5e-42 141.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 KFM76754.1 - 0.023 14.5 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin DDE_3 PF13358.6 KFM76755.1 - 1.7e-16 60.3 0.1 2.5e-15 56.5 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76755.1 - 1.5e-10 41.1 1.0 2.7e-10 40.4 1.0 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76756.1 - 3.6e-14 52.7 0.2 7.1e-13 48.5 0.0 2.7 1 1 2 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76756.1 - 1.4e-10 41.3 1.0 3.3e-10 40.0 1.0 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76757.1 - 6.9e-16 58.3 0.0 5.6e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76757.1 - 7.7e-16 58.1 6.5 1.4e-15 57.2 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76757.1 - 0.00071 20.1 1.5 0.00071 20.1 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76757.1 - 0.0024 17.6 0.1 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76757.1 - 0.015 15.4 0.1 0.064 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM76757.1 - 0.034 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM76758.1 - 2.3e-16 59.8 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76758.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ig_3 PF13927.6 KFM76761.1 - 6.6e-13 49.1 0.2 1.6e-05 25.4 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM76761.1 - 6.1e-07 29.4 0.0 0.00033 20.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM76761.1 - 7.3e-06 26.2 0.1 0.0051 17.1 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM76761.1 - 0.00051 20.2 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 KFM76761.1 - 0.00051 20.2 0.0 0.58 10.4 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain PKD PF00801.20 KFM76761.1 - 0.031 14.1 0.5 0.5 10.3 0.1 2.8 2 1 1 3 3 3 0 PKD domain DUF1180 PF06679.12 KFM76761.1 - 0.035 14.5 0.4 0.052 14.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HTH_Tnp_Tc5 PF03221.16 KFM76763.1 - 3.4e-16 59.0 0.1 6e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain KapB PF08810.10 KFM76763.1 - 0.11 12.6 0.3 0.5 10.6 0.1 1.9 1 1 1 2 2 2 0 Kinase associated protein B Es2 PF09751.9 KFM76764.1 - 1.3e-76 259.1 13.1 1.3e-76 259.1 13.1 2.6 2 1 0 2 2 2 1 Nuclear protein Es2 Sec3_C PF09763.9 KFM76766.1 - 1.8e-164 548.9 27.6 2.2e-164 548.6 27.6 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KFM76766.1 - 7.7e-27 93.3 3.5 2.1e-26 91.9 3.5 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH BST2 PF16716.5 KFM76766.1 - 1.2 9.8 5.7 0.49 11.0 0.2 3.2 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF5344 PF17279.2 KFM76766.1 - 3 8.5 8.7 1.5 9.5 0.1 4.5 5 1 1 6 6 6 0 Family of unknown function (DUF5344) Adaptin_N PF01602.20 KFM76767.1 - 5.4e-129 431.1 6.4 7.8e-129 430.6 6.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFM76767.1 - 2.9e-57 193.1 0.2 8e-57 191.6 0.2 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KFM76767.1 - 5.5e-39 132.9 0.1 1.1e-38 131.9 0.1 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KFM76767.1 - 1.6e-17 63.6 0.6 4e-06 27.1 0.0 5.7 4 1 0 5 5 5 4 HEAT repeats Cnd1 PF12717.7 KFM76767.1 - 4.7e-12 46.2 14.4 1.1e-05 25.6 0.6 5.6 4 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFM76767.1 - 3.8e-06 26.7 3.3 18 5.9 0.0 6.7 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 KFM76767.1 - 0.0039 17.7 0.2 0.1 13.1 0.1 3.6 5 0 0 5 5 5 1 HEAT-like repeat Nipped-B_C PF12830.7 KFM76767.1 - 0.025 14.5 2.9 3.5 7.5 0.0 3.4 2 1 1 3 3 3 0 Sister chromatid cohesion C-terminus B2-adapt-app_C PF09066.10 KFM76767.1 - 0.038 14.1 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain HEAT_PBS PF03130.16 KFM76767.1 - 0.058 14.1 0.2 22 6.1 0.0 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF3385 PF11865.8 KFM76767.1 - 0.37 10.7 2.6 42 4.0 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) DCP1 PF06058.13 KFM76768.1 - 6.8e-11 42.1 0.0 8.2e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Ion_trans PF00520.31 KFM76771.1 - 4.3e-107 356.9 33.6 6.9e-59 199.0 21.0 3.1 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 KFM76771.1 - 2.6e-05 23.1 31.3 0.00058 18.6 17.9 4.2 3 1 0 3 3 3 2 Polycystin cation channel DUF2722 PF10846.8 KFM76771.1 - 0.28 10.1 4.2 0.43 9.5 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Ion_trans PF00520.31 KFM76772.1 - 1.1e-13 50.9 0.3 1.3e-13 50.8 0.3 1.0 1 0 0 1 1 1 1 Ion transport protein HTH_32 PF13565.6 KFM76773.1 - 0.00015 22.3 1.1 0.00015 22.3 1.1 1.5 1 1 1 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76773.1 - 0.023 14.5 0.9 3.3 7.6 0.1 2.4 2 1 0 2 2 2 0 Homeodomain-like domain PCI PF01399.27 KFM76773.1 - 0.026 15.0 0.0 0.029 14.9 0.0 1.1 1 0 0 1 1 1 0 PCI domain Sigma70_r4 PF04545.16 KFM76773.1 - 0.027 14.0 0.1 0.047 13.2 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Terminase_4 PF05119.12 KFM76773.1 - 0.054 13.9 0.0 0.059 13.8 0.0 1.2 1 0 0 1 1 1 0 Phage terminase, small subunit HTH_17 PF12728.7 KFM76773.1 - 0.065 13.4 0.7 6.1 7.1 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KFM76773.1 - 0.071 13.4 0.4 0.071 13.4 0.4 1.6 2 0 0 2 2 2 0 Transposase ANT PF03374.14 KFM76773.1 - 0.073 13.4 0.0 0.092 13.1 0.0 1.2 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain HTH_10 PF04967.12 KFM76773.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Ion_trans PF00520.31 KFM76774.1 - 5.7e-41 140.4 14.9 6.5e-41 140.2 14.9 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM76774.1 - 0.00091 18.0 12.4 0.0099 14.6 1.8 2.0 1 1 1 2 2 2 2 Polycystin cation channel GPHH PF16905.5 KFM76775.1 - 8.4e-30 102.3 0.1 1.5e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ion_trans PF00520.31 KFM76775.1 - 2.9e-10 39.8 0.0 3.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ca_chan_IQ PF08763.11 KFM76775.1 - 0.0006 20.0 0.1 0.0012 19.0 0.1 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain EF-hand_11 PF08976.11 KFM76775.1 - 0.0064 17.3 0.0 0.024 15.5 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain PKD_channel PF08016.12 KFM76775.1 - 0.02 13.6 1.9 0.029 13.0 1.9 1.2 1 0 0 1 1 1 0 Polycystin cation channel EF-hand_1 PF00036.32 KFM76775.1 - 0.067 12.8 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 EF hand CAC1F_C PF16885.5 KFM76776.1 - 5.9e-10 39.4 0.0 8.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Voltage-gated calcium channel subunit alpha, C-term HTH_Crp_2 PF13545.6 KFM76776.1 - 0.0083 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KFM76776.1 - 0.17 11.5 0.1 2.1 8.0 0.0 2.3 1 1 1 2 2 2 0 Winged helix-turn-helix DNA-binding HAUS5 PF14817.6 KFM76777.1 - 3.3e-12 46.0 3.3 3.5e-12 45.9 3.3 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 PHM7_cyt PF14703.6 KFM76777.1 - 0.063 13.5 2.4 0.11 12.8 2.4 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Ets PF00178.22 KFM76779.1 - 2.4e-35 120.8 2.5 3.3e-35 120.4 2.5 1.2 1 0 0 1 1 1 1 Ets-domain FbpA PF05833.11 KFM76779.1 - 0.022 13.5 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HSF_DNA-bind PF00447.17 KFM76779.1 - 0.037 14.6 0.5 0.049 14.2 0.5 1.3 1 0 0 1 1 1 0 HSF-type DNA-binding Defensin_big PF14862.6 KFM76780.1 - 0.0063 16.8 0.3 0.0092 16.3 0.3 1.2 1 0 0 1 1 1 1 Big defensin Ovate PF04844.13 KFM76780.1 - 0.23 11.5 0.1 0.23 11.5 0.1 1.6 2 0 0 2 2 2 0 Transcriptional repressor, ovate WH1 PF00568.23 KFM76781.1 - 9.3e-34 115.7 1.5 1.4e-33 115.2 1.5 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KFM76781.1 - 8.5e-14 51.7 0.8 2.1e-13 50.4 0.8 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 KFM76781.1 - 1.2e-11 44.0 0.8 0.00018 21.2 0.0 2.4 2 0 0 2 2 2 2 WH2 motif Amidase_2 PF01510.25 KFM76782.1 - 2.5e-19 70.0 1.2 3.3e-19 69.6 1.2 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Amidase_2 PF01510.25 KFM76783.1 - 6e-18 65.5 0.1 8.5e-18 65.0 0.1 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Amidase_2 PF01510.25 KFM76784.1 - 9.3e-22 77.8 0.5 1.5e-21 77.2 0.5 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Amidase_2 PF01510.25 KFM76785.1 - 3.9e-18 66.1 0.1 5.1e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Amidase_2 PF01510.25 KFM76786.1 - 5.2e-18 65.7 0.1 6.8e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase DUF2730 PF10805.8 KFM76787.1 - 0.33 11.1 51.1 0.034 14.2 1.6 6.8 3 3 3 6 6 6 0 Protein of unknown function (DUF2730) Fez1 PF06818.15 KFM76787.1 - 0.42 11.0 74.1 0.88 10.0 10.5 4.2 2 1 2 4 4 4 0 Fez1 Pkinase PF00069.25 KFM76789.1 - 1.8e-60 204.5 0.0 2.4e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM76789.1 - 2.9e-30 105.4 0.0 3.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM76789.1 - 2.1e-08 33.8 0.0 7.5e-08 32.0 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFM76789.1 - 1.2e-05 24.3 1.2 2.2e-05 23.4 1.2 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFM76789.1 - 0.00021 20.7 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM76789.1 - 0.00023 21.2 0.1 0.16 11.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFM76789.1 - 0.0019 17.8 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 YihI PF04220.12 KFM76789.1 - 1.2 8.8 7.8 11 5.8 0.0 2.1 2 0 0 2 2 2 0 Der GTPase activator (YihI) MAM PF00629.23 KFM76790.1 - 3.6e-40 137.5 0.2 6.9e-32 110.6 0.0 2.1 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 KFM76790.1 - 2.5e-07 30.8 14.1 5e-07 29.8 14.1 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A HTH_Tnp_Tc3_2 PF01498.18 KFM76791.1 - 2.4e-16 59.7 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76791.1 - 9.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CNRIP1 PF15043.6 KFM76792.1 - 1.2e-22 80.2 0.1 1.3e-22 80.1 0.1 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 RNaseH_like PF04308.12 KFM76792.1 - 0.03 14.2 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease H-like ENT PF03735.14 KFM76793.1 - 0.072 13.2 0.7 0.098 12.7 0.4 1.5 1 1 0 1 1 1 0 ENT domain HTH_Tnp_Tc3_2 PF01498.18 KFM76794.1 - 0.00054 20.2 2.0 0.00058 20.1 0.4 1.9 2 0 0 2 2 2 1 Transposase MmoB_DmpM PF02406.17 KFM76794.1 - 0.048 13.9 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 MmoB/DmpM family NUMOD1 PF07453.13 KFM76794.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain Metallophos PF00149.28 KFM76795.1 - 0.005 17.4 1.4 0.012 16.1 0.3 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Autophagy_act_C PF03987.15 KFM76796.1 - 2.1e-18 66.6 4.9 3.9e-18 65.8 4.9 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain SCAPER_N PF16501.5 KFM76797.1 - 8.8e-42 141.1 0.1 8.8e-42 141.1 0.1 3.3 4 0 0 4 4 4 1 S phase cyclin A-associated protein in the endoplasmic reticulum zf-met PF12874.7 KFM76797.1 - 1.3e-06 28.6 0.2 4.4e-06 26.9 0.2 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM76797.1 - 0.0043 17.3 0.1 0.016 15.5 0.1 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding OMPdecase PF00215.24 KFM76798.1 - 5.7e-71 238.7 0.1 1e-70 237.9 0.1 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 KFM76798.1 - 2.7e-11 43.3 0.2 8.9e-11 41.6 0.2 1.9 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Dimer_Tnp_hAT PF05699.14 KFM76799.1 - 1.2e-09 37.9 0.2 1.4e-09 37.6 0.2 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3776 PF12618.8 KFM76799.1 - 0.011 16.3 0.0 0.011 16.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) SPARC_Ca_bdg PF10591.9 KFM76800.1 - 8.3e-23 80.9 3.7 8.3e-23 80.9 3.7 2.6 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 KFM76800.1 - 1.2e-13 50.5 2.6 1.2e-13 50.5 2.6 2.5 1 1 1 2 2 2 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.15 KFM76800.1 - 3.8e-09 36.5 6.7 3.8e-09 36.5 6.7 2.9 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM76800.1 - 0.0036 17.3 5.4 0.0036 17.3 5.4 2.7 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFM76800.1 - 0.015 15.7 0.3 0.037 14.5 0.3 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KFM76800.1 - 0.031 14.1 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KFM76800.1 - 0.034 13.7 2.8 0.041 13.4 0.0 2.7 3 0 0 3 3 3 0 EF hand 7tm_2 PF00002.24 KFM76804.1 - 2.3e-18 66.4 11.1 2.6e-18 66.2 11.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KFM76804.1 - 0.038 13.1 6.4 0.047 12.8 6.4 1.0 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor TraL PF07178.11 KFM76804.1 - 0.19 12.2 0.4 0.19 12.2 0.4 2.0 1 1 1 2 2 2 0 TraL protein Lectin_N PF03954.14 KFM76804.1 - 0.57 9.9 3.3 0.24 11.1 0.5 1.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain YesK PF14150.6 KFM76804.1 - 4.1 7.6 10.7 3 8.1 6.5 2.3 1 1 1 2 2 2 0 YesK-like protein 7tm_2 PF00002.24 KFM76805.1 - 1.2e-05 24.8 0.2 1.3e-05 24.7 0.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HTH_Tnp_Tc3_2 PF01498.18 KFM76807.1 - 2.2e-16 59.8 2.2 4.6e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76807.1 - 9.8e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease FOXP-CC PF16159.5 KFM76810.1 - 5.6e-33 113.4 5.3 5.6e-33 113.4 5.3 3.4 3 0 0 3 3 3 1 FOXP coiled-coil domain Forkhead PF00250.18 KFM76810.1 - 1.2e-27 96.0 0.5 3.8e-27 94.4 0.2 2.0 2 0 0 2 2 2 1 Forkhead domain SMN PF06003.12 KFM76810.1 - 0.49 9.6 6.7 1.3 8.3 6.7 1.6 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) AIG1 PF04548.16 KFM76810.1 - 1.9 7.8 8.8 4.4 6.6 8.8 1.6 1 0 0 1 1 1 0 AIG1 family DUF4685 PF15737.5 KFM76810.1 - 3 8.3 12.5 1.9 8.9 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) Zona_pellucida PF00100.23 KFM76811.1 - 3e-05 23.9 1.7 4.7e-05 23.3 1.7 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain SIT PF15330.6 KFM76811.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Corona_S2 PF01601.16 KFM76811.1 - 0.16 10.5 2.5 0.23 9.9 2.5 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Tnp_P_element PF12017.8 KFM76813.1 - 3e-13 49.7 0.4 5.3e-13 48.9 0.4 1.4 1 0 0 1 1 1 1 Transposase protein COQ7 PF03232.13 KFM76814.1 - 9.1e-62 207.8 0.0 1.1e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KFM76814.1 - 5.9e-05 23.5 0.0 0.00012 22.5 0.0 1.5 1 1 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.6 KFM76814.1 - 0.0013 18.9 0.3 0.11 12.7 0.0 2.3 1 1 1 2 2 2 2 Ferritin-like domain SNURF PF07192.11 KFM76814.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 SNURF/RPN4 protein Nrf1_DNA-bind PF10491.9 KFM76815.1 - 5.5e-118 392.2 0.2 9e-118 391.5 0.2 1.3 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Nrf1_activ_bdg PF10492.9 KFM76815.1 - 1.4e-07 32.0 16.5 4.2e-07 30.5 5.9 2.8 2 0 0 2 2 2 2 Nrf1 activator activation site binding domain Hydrolase_6 PF13344.6 KFM76815.1 - 0.051 13.7 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RabGAP-TBC PF00566.18 KFM76816.1 - 7.1e-40 137.0 2.3 7.1e-40 137.0 2.3 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TIMELESS_C PF05029.13 KFM76816.1 - 0.12 11.5 7.7 0.19 10.8 7.7 1.2 1 0 0 1 1 1 0 Timeless protein C terminal region DDE_3 PF13358.6 KFM76817.1 - 1e-14 54.5 0.0 1.3e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_C48 PF02902.19 KFM76818.1 - 9.3e-37 127.0 0.2 1.7e-36 126.1 0.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RNA_pol_Rpc4 PF05132.14 KFM76818.1 - 0.15 12.5 10.2 0.22 12.0 0.8 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Na_trans_assoc PF06512.13 KFM76818.1 - 2.7 8.2 24.5 0.26 11.5 0.4 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated SDA1 PF05285.12 KFM76818.1 - 9.2 5.6 25.8 9.7 5.5 18.1 2.2 2 0 0 2 2 2 0 SDA1 DDE_3 PF13358.6 KFM76819.1 - 2.2e-14 53.4 0.0 2.5e-13 50.0 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76819.1 - 1.4e-10 41.3 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_Tnp_1_7 PF13843.6 KFM76820.1 - 2.5e-19 69.8 0.0 3.3e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 C1_2 PF03107.16 KFM76820.1 - 0.0096 16.2 3.9 0.025 14.9 3.9 1.7 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 KFM76820.1 - 0.11 12.3 9.0 0.26 11.2 9.0 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tom5 PF10642.9 KFM76821.1 - 0.0089 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase AFG1_ATPase PF03969.16 KFM76822.1 - 2.9e-51 174.5 0.0 3.4e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 AFG1-like ATPase ATPase_2 PF01637.18 KFM76822.1 - 1.2e-05 25.3 0.2 2.1e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFM76822.1 - 0.00089 19.3 0.1 0.0019 18.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFM76822.1 - 0.00099 19.5 0.0 0.049 14.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM76822.1 - 0.01 16.1 0.1 0.038 14.2 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KFM76822.1 - 0.011 16.1 0.0 0.065 13.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KFM76822.1 - 0.023 14.2 0.0 0.035 13.6 0.0 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KFM76822.1 - 0.04 14.3 0.0 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Mrx7 PF10906.8 KFM76822.1 - 0.047 13.9 0.9 0.093 13.0 0.1 1.9 2 0 0 2 2 2 0 MIOREX complex component 7 TniB PF05621.11 KFM76822.1 - 0.07 12.5 0.0 0.21 11.0 0.0 1.8 1 1 1 2 2 2 0 Bacterial TniB protein Bac_DnaA PF00308.18 KFM76822.1 - 0.074 12.9 0.6 0.25 11.2 0.1 2.0 3 0 0 3 3 3 0 Bacterial dnaA protein DAP3 PF10236.9 KFM76822.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.22 KFM76822.1 - 0.097 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KFM76822.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KFM76822.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AFG1_ATPase PF03969.16 KFM76823.1 - 6.1e-08 31.9 0.0 6.5e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 AFG1-like ATPase Chlam_OMP3 PF03503.13 KFM76823.1 - 0.051 13.9 0.3 0.084 13.2 0.3 1.4 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 MADF_DNA_bdg PF10545.9 KFM76825.1 - 1.5e-08 34.8 3.4 3.4e-08 33.7 3.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like PuR_N PF09182.10 KFM76825.1 - 0.77 9.7 0.0 0.77 9.7 0.0 3.2 4 0 0 4 4 4 0 Bacterial purine repressor, N-terminal BESS PF02944.20 KFM76826.1 - 2.8e-05 23.8 0.2 5.5e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 BESS motif Integrase_H2C2 PF17921.1 KFM76827.1 - 7.5e-11 42.0 0.4 9.3e-11 41.7 0.4 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM76827.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 H2C2 zinc finger Ceramidase_alk PF04734.13 KFM76828.1 - 2e-92 310.4 0.0 2.2e-92 310.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal HSP70 PF00012.20 KFM76829.1 - 5.1e-72 242.9 1.2 5.6e-72 242.8 1.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM76829.1 - 2.3e-12 46.4 0.1 2.7e-12 46.2 0.1 1.0 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KFM76829.1 - 0.003 16.9 0.3 0.0044 16.3 0.3 1.4 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase StbA PF06406.11 KFM76829.1 - 0.069 12.4 0.1 0.082 12.1 0.1 1.3 1 1 0 1 1 1 0 StbA protein DDR PF08841.10 KFM76829.1 - 0.073 12.0 0.2 0.097 11.6 0.1 1.3 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DeoC PF01791.9 KFM76829.1 - 0.1 12.2 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 DeoC/LacD family aldolase I-set PF07679.16 KFM76830.1 - 1e-14 54.4 0.4 2.8e-14 53.0 0.2 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM76830.1 - 4.2e-12 46.5 0.0 1.2e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM76830.1 - 2.6e-09 37.1 0.2 6e-09 36.0 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin domain fn3 PF00041.21 KFM76830.1 - 2.7e-09 37.3 0.4 9.5e-09 35.5 0.2 1.9 2 0 0 2 2 2 1 Fibronectin type III domain Ig_2 PF13895.6 KFM76830.1 - 2.7e-07 30.8 0.0 1.1e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM76830.1 - 0.0002 21.3 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM76830.1 - 0.0028 18.0 0.1 0.0057 17.0 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFM76830.1 - 0.0067 16.8 0.3 0.036 14.5 0.2 2.2 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM76830.1 - 0.011 16.0 0.2 0.027 14.7 0.2 1.8 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain SusE PF14292.6 KFM76830.1 - 0.057 13.6 0.2 0.73 10.1 0.0 2.1 1 1 0 2 2 2 0 SusE outer membrane protein fn3 PF00041.21 KFM76831.1 - 8.9e-15 54.8 0.0 1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Fibronectin type III domain fn3_2 PF16893.5 KFM76831.1 - 0.036 14.2 0.0 0.04 14.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin type III domain Tam41_Mmp37 PF09139.11 KFM76834.1 - 1.7e-113 379.3 2.1 2e-113 379.1 2.1 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DDE_3 PF13358.6 KFM76835.1 - 5e-16 58.8 0.1 5.7e-15 55.3 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76835.1 - 8.1e-16 58.0 6.5 1.5e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFM76835.1 - 8.3e-05 22.3 0.0 0.0033 17.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76835.1 - 0.00063 20.3 2.0 0.00063 20.3 2.0 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76835.1 - 0.0016 18.5 0.1 0.0061 16.7 0.1 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM76835.1 - 0.021 14.7 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase HTH_29 PF13551.6 KFM76835.1 - 0.044 13.8 1.8 0.064 13.3 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix TBP-binding PF09247.11 KFM76836.1 - 1.6e-06 28.3 20.4 8.8 6.7 0.1 9.7 8 2 2 10 10 10 1 TATA box-binding protein binding ABA_WDS PF02496.16 KFM76836.1 - 1.8e-06 28.3 6.8 1.6 9.2 0.1 5.6 3 2 4 7 7 7 3 ABA/WDS induced protein DUF236 PF03057.14 KFM76836.1 - 0.011 15.6 0.0 30 4.7 0.0 4.7 5 0 0 5 5 5 0 DUF236 repeat ATP_bind_3 PF01171.20 KFM76836.1 - 0.3 10.8 9.4 3.3 7.4 0.2 4.2 1 1 4 5 5 5 0 PP-loop family tRNA_NucTransf2 PF09249.11 KFM76836.1 - 1 9.6 5.3 1e+02 3.2 0.1 4.7 3 1 3 6 6 6 0 tRNA nucleotidyltransferase, second domain FAM181 PF15238.6 KFM76836.1 - 1.1 9.0 17.7 0.83 9.4 1.2 3.7 1 1 3 4 4 4 0 FAM181 Cupin_8 PF13621.6 KFM76837.1 - 4.6e-13 49.5 0.0 5e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFM76837.1 - 0.0042 16.6 0.1 0.0042 16.6 0.1 1.1 1 0 0 1 1 1 1 Cupin superfamily protein NopRA1 PF16201.5 KFM76837.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 Ependymin PF00811.18 KFM76839.1 - 0.0019 18.5 0.2 2.9 8.2 0.0 2.7 2 0 0 2 2 2 2 Ependymin TGFb_propeptide PF00688.18 KFM76839.1 - 0.092 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 TGF-beta propeptide Insulin_TMD PF17870.1 KFM76839.1 - 0.25 11.4 1.4 0.82 9.8 1.4 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF1640 PF07798.11 KFM76840.1 - 0.0016 18.5 5.4 0.0016 18.5 5.4 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1640) Spore_III_AB PF09548.10 KFM76840.1 - 0.0023 18.1 2.6 0.0023 18.1 2.6 1.9 2 1 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) PheRS_DBD2 PF18554.1 KFM76840.1 - 0.011 15.7 0.8 7.3 6.7 0.0 3.1 2 1 1 3 3 3 0 PheRS DNA binding domain 2 PTPS PF01242.19 KFM76840.1 - 0.035 14.1 1.1 0.051 13.5 0.3 1.7 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase DUF1117 PF06547.12 KFM76840.1 - 0.072 13.6 0.4 0.072 13.6 0.4 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1117) DUF3994 PF13159.6 KFM76840.1 - 0.072 13.6 0.3 1.4 9.5 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3994) Strep_SA_rep PF06696.11 KFM76840.1 - 0.17 11.9 11.3 3.1 7.9 1.0 3.6 3 0 0 3 3 3 0 Streptococcal surface antigen repeat DUF148 PF02520.17 KFM76840.1 - 0.25 11.4 9.1 0.12 12.5 3.6 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF2089 PF09862.9 KFM76840.1 - 0.27 11.3 3.7 0.17 12.0 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2089) CdvA PF18822.1 KFM76840.1 - 0.38 10.6 10.0 0.055 13.3 4.3 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain COG2 PF06148.11 KFM76840.1 - 0.91 9.6 8.9 1.4 9.0 1.1 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 WXG100 PF06013.12 KFM76840.1 - 0.91 9.8 11.9 0.059 13.6 5.8 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG 60KD_IMP PF02096.20 KFM76840.1 - 3.5 7.5 8.0 4.8 7.1 3.1 2.3 1 1 1 2 2 2 0 60Kd inner membrane protein GBP_C PF02841.14 KFM76840.1 - 7.2 5.9 17.3 0.13 11.6 8.4 2.3 3 0 0 3 3 3 0 Guanylate-binding protein, C-terminal domain DUF740 PF05340.12 KFM76840.1 - 10 4.8 11.1 3.3 6.3 8.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF740) gag-asp_proteas PF13975.6 KFM76841.1 - 3.4e-11 43.5 0.0 9.9e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM76841.1 - 1.2e-08 35.5 0.0 2.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KFM76841.1 - 0.00072 19.8 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KFM76841.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease Trypsin PF00089.26 KFM76842.1 - 1.7e-11 44.4 0.0 1.7e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM76842.1 - 0.12 13.3 0.0 0.13 13.2 0.0 1.1 1 0 0 1 1 1 0 Trypsin-like peptidase domain 2Fe-2S_thioredx PF01257.19 KFM76843.1 - 1.6e-62 209.7 0.0 2e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin CUE PF02845.16 KFM76846.1 - 3.9e-13 48.8 0.2 5.5e-13 48.3 0.2 1.2 1 0 0 1 1 1 1 CUE domain AbiEi_3 PF11459.8 KFM76846.1 - 0.0044 16.7 0.0 0.0044 16.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system zf-H2C2_2 PF13465.6 KFM76847.1 - 4.2e-57 188.2 89.6 8.2e-07 29.2 0.1 13.6 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76847.1 - 1.8e-46 154.0 98.6 0.00015 22.0 0.1 13.9 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76847.1 - 3.1e-42 139.6 92.3 0.00032 21.3 0.1 13.9 14 0 0 14 14 14 13 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM76847.1 - 3.3e-21 75.0 77.6 0.0056 16.9 0.2 13.3 13 1 0 13 13 13 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM76847.1 - 4.1e-21 74.7 90.2 0.0012 19.2 0.7 14.0 14 0 0 14 14 14 10 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM76847.1 - 4.5e-16 58.4 89.5 0.0012 18.7 0.2 13.6 14 0 0 14 14 14 8 C2H2-type zinc finger zf-Di19 PF05605.12 KFM76847.1 - 0.00069 19.9 65.9 0.44 10.9 3.9 8.8 1 1 8 10 10 10 4 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFM76847.1 - 0.0071 16.6 17.8 9.7 6.6 1.3 6.9 5 3 1 6 6 5 1 BolA-like protein ADK_lid PF05191.14 KFM76847.1 - 0.041 13.9 1.1 0.041 13.9 1.1 8.0 7 1 2 9 9 9 0 Adenylate kinase, active site lid DZR PF12773.7 KFM76847.1 - 0.094 12.8 49.2 0.48 10.5 3.2 7.5 2 2 2 4 4 3 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 KFM76847.1 - 0.18 11.9 52.6 7.7 6.7 0.3 11.6 10 2 2 12 12 12 0 Sec23/Sec24 zinc finger DUF4499 PF14934.6 KFM76847.1 - 0.19 12.1 1.5 13 6.2 0.0 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4499) GAGA PF09237.11 KFM76847.1 - 1 9.2 9.6 42 4.0 0.0 6.1 7 1 1 8 8 8 0 GAGA factor zf-H2C2_2 PF13465.6 KFM76848.1 - 3.7e-71 232.6 99.6 3.4e-07 30.4 3.4 14.6 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76848.1 - 8.6e-55 180.3 123.6 1.9e-05 24.9 0.8 14.2 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76848.1 - 5.6e-41 135.7 113.1 0.00039 21.0 0.7 14.2 14 0 0 14 14 14 14 C2H2-type zinc finger zf-met PF12874.7 KFM76848.1 - 9.7e-26 89.4 102.6 0.00012 22.4 1.6 14.1 14 0 0 14 14 13 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM76848.1 - 9.4e-15 54.5 84.7 0.00051 20.2 1.6 13.4 14 0 0 14 14 13 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM76848.1 - 1e-12 47.7 94.5 0.0076 16.2 0.4 14.3 14 0 0 14 14 14 9 C2H2-type zinc finger BolA PF01722.18 KFM76848.1 - 2.6e-05 24.4 11.5 0.77 10.1 0.0 7.1 4 2 4 8 8 8 1 BolA-like protein zf_UBZ PF18439.1 KFM76848.1 - 0.097 12.3 64.5 0.5 10.0 0.0 13.0 14 0 0 14 14 14 0 Ubiquitin-Binding Zinc Finger DUF4157 PF13699.6 KFM76848.1 - 0.15 12.3 0.0 13 6.1 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) Zn-ribbon_8 PF09723.10 KFM76848.1 - 3.5 7.8 56.2 3.4 7.9 3.5 9.8 2 2 9 11 11 11 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 KFM76848.1 - 7.2 7.3 56.2 9.3 7.0 0.3 10.0 2 2 4 7 7 6 0 Zinc finger C2H2-type, 3 repeats zf-CCHC_4 PF14392.6 KFM76849.1 - 0.42 10.4 15.1 0.41 10.4 1.7 2.7 3 0 0 3 3 3 0 Zinc knuckle HTH_Tnp_Tc3_2 PF01498.18 KFM76850.1 - 2.3e-16 59.8 2.2 5e-16 58.7 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76850.1 - 1.1e-13 51.1 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_48 PF17906.1 KFM76850.1 - 4.1e-07 30.0 0.1 7.8e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Bromo_TP PF07524.13 KFM76852.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 KFM76852.1 - 0.0019 18.4 0.2 0.0039 17.3 0.0 1.6 2 0 0 2 2 2 1 Histone-fold protein TFIIS_C PF01096.18 KFM76853.1 - 1.3e-15 56.9 3.7 1.3e-15 56.9 3.7 2.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 KFM76853.1 - 3.3e-06 27.0 3.8 0.035 14.1 0.1 2.3 2 0 0 2 2 2 2 Double zinc ribbon RNA_POL_M_15KD PF02150.16 KFM76853.1 - 0.0023 17.8 4.7 0.19 11.6 0.2 3.2 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.6 KFM76853.1 - 0.014 14.8 12.5 3.6 7.1 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KFM76853.1 - 0.064 13.0 10.6 3.1 7.6 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DUF3716 PF12511.8 KFM76853.1 - 0.064 13.3 1.2 0.064 13.3 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) FYVE_2 PF02318.16 KFM76853.1 - 0.082 13.1 3.9 2.6 8.3 1.4 2.1 1 1 0 2 2 2 0 FYVE-type zinc finger Rpr2 PF04032.16 KFM76853.1 - 0.091 13.1 3.1 0.55 10.6 3.1 2.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-Di19 PF05605.12 KFM76853.1 - 0.11 12.8 3.4 1.7 9.0 0.0 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.29 KFM76853.1 - 0.13 12.1 4.8 1.2 9.0 0.5 2.5 2 0 0 2 2 2 0 PHD-finger A2L_zn_ribbon PF08792.10 KFM76853.1 - 0.29 10.9 9.6 0.41 10.4 0.1 3.5 4 0 0 4 4 4 0 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KFM76853.1 - 0.47 10.4 8.1 6.1 6.9 3.3 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain HypA PF01155.19 KFM76853.1 - 0.55 10.3 5.8 7.6 6.6 5.8 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nudix_N_2 PF14803.6 KFM76853.1 - 0.62 10.0 7.4 18 5.3 1.6 3.8 3 1 0 3 3 3 0 Nudix N-terminal CpXC PF14353.6 KFM76853.1 - 0.68 10.0 4.2 1.1 9.3 2.4 2.2 2 1 0 2 2 1 0 CpXC protein C1_2 PF03107.16 KFM76853.1 - 1.4 9.3 9.3 8.5 6.8 0.2 3.2 2 1 0 2 2 2 0 C1 domain DNA_RNApol_7kD PF03604.13 KFM76853.1 - 1.9 8.2 12.1 0.18 11.5 0.6 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Elf1 PF05129.13 KFM76853.1 - 2 8.5 7.4 9.7 6.3 5.4 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-IS66 PF13005.7 KFM76853.1 - 2.4 8.6 9.6 35 4.9 0.1 3.4 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Zn_Tnp_IS1595 PF12760.7 KFM76853.1 - 2.6 8.1 11.2 10 6.2 0.5 3.6 3 1 0 3 3 3 0 Transposase zinc-ribbon domain zf-TFIIB PF13453.6 KFM76853.1 - 2.9 7.3 8.7 18 4.7 2.7 2.9 2 1 1 3 3 3 0 Transcription factor zinc-finger Prok-RING_1 PF14446.6 KFM76853.1 - 5.9 6.9 9.9 0.96 9.4 1.3 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 RecR PF02132.15 KFM76853.1 - 6.4 6.4 12.8 1.5 8.4 1.3 3.2 3 1 0 3 3 3 0 RecR protein zinc_ribbon_15 PF17032.5 KFM76853.1 - 6.4 7.6 14.4 96 3.8 0.2 3.7 2 1 0 2 2 2 0 zinc-ribbon family zinc_ribbon_10 PF10058.9 KFM76853.1 - 7.1 6.4 9.2 6 6.7 2.5 3.0 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-FPG_IleRS PF06827.14 KFM76853.1 - 8.9 6.3 9.9 5.2 7.0 0.2 3.0 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS CP2 PF04516.15 KFM76854.1 - 7.6e-56 189.0 0.1 1.1e-55 188.4 0.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor Ank_2 PF12796.7 KFM76855.1 - 2.5e-08 34.4 0.0 0.00016 22.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM76855.1 - 5.3e-08 33.0 0.0 2.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM76855.1 - 2.4e-07 31.1 0.1 4.9e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM76855.1 - 2.3e-06 27.5 0.3 0.0092 16.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KFM76855.1 - 8.8e-05 22.8 0.2 0.034 14.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Cauli_VI PF01693.16 KFM76855.1 - 0.0018 18.6 0.2 0.0056 17.0 0.0 1.9 2 0 0 2 2 2 1 Caulimovirus viroplasmin Maelstrom PF13017.6 KFM76857.1 - 2.8e-38 131.8 0.9 4.6e-38 131.1 0.9 1.3 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.10 KFM76857.1 - 3.2e-10 40.4 1.0 8e-10 39.2 1.0 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KFM76857.1 - 3.6e-05 24.1 2.4 8.5e-05 22.9 2.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DUF3292 PF11696.8 KFM76858.1 - 1.5 7.1 10.7 1.9 6.7 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) SPRY PF00622.28 KFM76860.1 - 2.5e-21 76.0 0.0 4.4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 KFM76860.1 - 5.8e-10 39.4 4.1 1.1e-09 38.5 4.1 1.5 1 0 0 1 1 1 1 SOCS box DDE_1 PF03184.19 KFM76864.1 - 7.7e-24 84.3 0.0 1.4e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Baculo_E56 PF04639.12 KFM76864.1 - 0.003 16.9 2.5 0.003 16.9 2.5 1.5 2 0 0 2 2 2 1 Baculoviral E56 protein, specific to ODV envelope DUF1065 PF06358.11 KFM76864.1 - 0.053 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) Mto2_bdg PF12808.7 KFM76864.1 - 0.49 10.7 7.3 1.3 9.4 7.3 1.7 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Mo25 PF08569.11 KFM76864.1 - 0.74 9.1 4.4 1.2 8.5 4.4 1.3 1 0 0 1 1 1 0 Mo25-like Atg14 PF10186.9 KFM76864.1 - 0.76 8.8 6.8 1.2 8.2 6.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TEX13 PF15186.6 KFM76864.1 - 3.4 7.4 11.4 0.48 10.1 6.1 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF1640 PF07798.11 KFM76864.1 - 7.1 6.6 11.8 31 4.6 11.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) YtxH PF12732.7 KFM76864.1 - 8.7 7.0 8.4 2.1e+02 2.5 8.4 2.7 1 1 0 1 1 1 0 YtxH-like protein ODV-E18 PF10717.9 KFM76865.1 - 0.011 15.5 1.1 0.012 15.4 1.1 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 HEAT PF02985.22 KFM76867.1 - 4.3e-07 29.6 0.5 0.035 14.4 0.1 2.6 2 0 0 2 2 2 2 HEAT repeat Cnd1 PF12717.7 KFM76867.1 - 5.6e-07 29.7 0.5 2.4e-06 27.7 0.5 1.8 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KFM76867.1 - 0.00029 21.0 3.4 0.0056 16.8 0.4 1.6 1 1 1 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KFM76867.1 - 0.0011 19.3 0.2 0.0039 17.5 0.1 1.8 1 1 1 2 2 2 2 HEAT repeats RICTOR_N PF14664.6 KFM76867.1 - 0.0014 17.7 2.1 0.0016 17.5 2.1 1.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KFM76867.1 - 0.023 15.1 0.6 1.2 9.6 0.1 2.3 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RIX1 PF08167.12 KFM76867.1 - 0.025 14.3 0.4 0.042 13.6 0.4 1.4 1 1 0 1 1 1 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 KFM76867.1 - 0.036 14.6 0.2 6.9 7.3 0.0 2.3 2 0 0 2 2 2 0 HEAT-like repeat Cohesin_HEAT PF12765.7 KFM76867.1 - 0.064 13.6 0.1 4.4 7.7 0.0 2.4 2 1 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.7 KFM76867.1 - 0.11 13.1 1.0 0.17 12.5 0.9 1.4 1 1 0 1 1 1 0 Vacuolar 14 Fab1-binding region Transposase_31 PF04754.12 KFM76869.1 - 0.027 14.1 0.0 0.027 14.1 0.0 1.0 1 0 0 1 1 1 0 Putative transposase, YhgA-like Cnd1 PF12717.7 KFM76870.1 - 1.3e-45 155.4 0.3 6.8e-44 149.8 0.1 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFM76870.1 - 4.1e-11 42.1 4.0 2.2e-10 39.7 1.3 2.7 1 1 1 2 2 2 1 Adaptin N terminal region Cnd3 PF12719.7 KFM76870.1 - 1.9e-07 30.6 0.9 8.9e-07 28.4 0.8 2.3 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KFM76870.1 - 3.2e-07 30.0 1.8 0.02 15.1 0.0 4.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KFM76870.1 - 7.2e-06 26.3 0.1 0.046 14.1 0.0 2.7 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 KFM76870.1 - 0.00022 21.7 0.0 0.42 11.2 0.0 3.5 3 0 0 3 3 3 1 HEAT-like repeat Cohesin_HEAT PF12765.7 KFM76870.1 - 0.005 17.1 7.6 0.026 14.8 0.1 4.1 4 1 1 5 5 5 1 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 KFM76870.1 - 0.015 15.5 0.7 2.1 8.6 0.1 3.1 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Vitellogenin_N PF01347.22 KFM76870.1 - 0.026 12.9 0.1 0.039 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region AnfG_VnfG PF03139.15 KFM76870.1 - 0.092 12.8 0.1 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit Homeodomain PF00046.29 KFM76871.1 - 1.7e-23 82.2 5.9 3e-23 81.4 5.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM76871.1 - 2.6e-05 24.0 1.0 8.5e-05 22.4 0.9 1.9 2 0 0 2 2 2 1 Homeobox KN domain DDE_3 PF13358.6 KFM76872.1 - 3e-10 40.0 0.0 3.5e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PurA PF04845.13 KFM76873.1 - 3.1e-103 343.8 0.1 3.6e-103 343.6 0.1 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein EFG_C PF00679.24 KFM76873.1 - 0.0048 16.9 0.1 2.6 8.1 0.0 2.7 3 0 0 3 3 3 2 Elongation factor G C-terminus DUF3276 PF11680.8 KFM76873.1 - 0.0052 16.9 0.5 5.3 7.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3276) G-alpha PF00503.20 KFM76875.1 - 1.6e-46 159.1 0.4 2e-46 158.8 0.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFM76875.1 - 5.6e-07 29.2 0.1 1.1e-06 28.2 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Urotensin_II PF02083.15 KFM76875.1 - 3.1 7.7 4.9 1.1 9.0 1.0 2.3 2 0 0 2 2 2 0 Urotensin II Holin_BlyA PF05102.12 KFM76876.1 - 0.0096 15.9 0.8 0.012 15.6 0.8 1.1 1 0 0 1 1 1 1 holin, BlyA family DUF4538 PF15061.6 KFM76876.1 - 0.18 11.5 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) CPBP PF02517.16 KFM76877.1 - 1.4e-07 31.8 1.6 1.4e-07 31.8 1.6 2.4 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Voltage_CLC PF00654.20 KFM76877.1 - 0.03 13.6 1.5 0.042 13.1 1.5 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel Phage_holin_1 PF04531.13 KFM76877.1 - 0.13 12.8 3.2 0.15 12.6 0.1 2.4 3 0 0 3 3 3 0 Bacteriophage holin DDE_3 PF13358.6 KFM76878.1 - 1.1e-14 54.4 0.0 1.4e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Mito_carr PF00153.27 KFM76879.1 - 1.2e-70 233.5 3.6 4.8e-24 84.1 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein bZIP_1 PF00170.21 KFM76881.1 - 1.9e-06 27.9 12.4 3.2e-06 27.1 12.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFM76881.1 - 9e-05 22.9 9.5 0.00011 22.6 8.9 1.5 1 1 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KFM76881.1 - 0.0017 18.4 11.3 0.0034 17.4 11.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper ASD2 PF08687.11 KFM76881.1 - 0.0023 17.6 1.2 0.003 17.2 1.2 1.2 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Macoilin PF09726.9 KFM76881.1 - 0.22 10.1 4.3 0.28 9.7 4.3 1.2 1 0 0 1 1 1 0 Macoilin family Neur_chan_memb PF02932.16 KFM76882.1 - 1.9e-18 67.4 3.1 2e-18 67.3 3.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DDE_3 PF13358.6 KFM76883.1 - 5.8e-16 58.6 0.1 6.6e-15 55.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76883.1 - 6.5e-16 58.3 6.5 1.6e-15 57.1 6.5 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM76883.1 - 0.00077 20.0 1.5 0.00077 20.0 1.5 2.9 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76883.1 - 0.003 17.3 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76883.1 - 0.017 15.2 0.1 0.069 13.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM76883.1 - 0.037 14.0 2.6 0.037 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM76884.1 - 3.9e-16 59.1 0.9 1.3e-15 57.3 0.8 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76884.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM76884.1 - 0.0054 17.3 0.1 0.024 15.2 0.1 2.2 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 KFM76885.1 - 9.4e-09 35.2 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76886.1 - 2.1e-16 59.9 2.2 4.4e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76886.1 - 9.2e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 KFM76887.1 - 3.2e-69 233.9 0.1 4.6e-69 233.4 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM76887.1 - 0.00014 22.6 12.1 0.00014 22.6 12.1 2.1 2 0 0 2 2 2 1 DDE_Tnp_1-like zinc-ribbon DDE_3 PF13358.6 KFM76888.1 - 5.1e-06 26.3 0.0 6.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76890.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76890.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM76891.1 - 2.6e-16 59.7 0.1 3.2e-15 56.1 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76891.1 - 1.4e-10 41.2 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase RRM_1 PF00076.22 KFM76892.1 - 4.8e-16 58.3 0.0 1.9e-06 27.6 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KFM76892.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pkinase_Tyr PF07714.17 KFM76893.1 - 1.9e-87 292.8 0.0 2.8e-87 292.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM76893.1 - 7.8e-43 146.7 0.0 1.1e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GTPase_binding PF09027.10 KFM76893.1 - 8.2e-20 70.6 0.7 2.1e-19 69.3 0.3 1.8 2 0 0 2 2 2 1 GTPase binding SH3_1 PF00018.28 KFM76893.1 - 1.1e-06 28.1 0.2 2.2e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM76893.1 - 5.8e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.6 KFM76893.1 - 0.00041 19.8 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SH3_2 PF07653.17 KFM76893.1 - 0.0027 17.3 0.1 0.0069 16.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 KFM76893.1 - 0.0083 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM76893.1 - 0.0086 15.4 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM76893.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PI3_PI4_kinase PF00454.27 KFM76894.1 - 7e-45 153.8 0.1 5.3e-31 108.3 0.1 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFM76894.1 - 1.3e-24 86.6 0.0 2.1e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KFM76894.1 - 0.11 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DUF3453 PF11935.8 KFM76895.1 - 0.0018 18.0 1.9 0.16 11.6 0.0 3.8 4 1 0 5 5 5 2 Domain of unknown function (DUF3453) Transposase_1 PF01359.18 KFM76898.1 - 7.1e-23 80.2 0.3 1.3e-22 79.4 0.3 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) AA_permease_2 PF13520.6 KFM76899.1 - 8.9e-12 44.6 11.3 1.8e-11 43.6 11.6 1.4 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFM76899.1 - 0.0076 14.9 9.4 0.01 14.5 7.8 1.8 1 1 1 2 2 2 1 Amino acid permease AA_permease_2 PF13520.6 KFM76900.1 - 0.00092 18.1 0.4 0.00096 18.1 0.4 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 KFM76901.1 - 4.4e-63 213.1 0.0 6.1e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM76901.1 - 9.9e-40 136.5 0.0 1.6e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CNH PF00780.22 KFM76901.1 - 5e-11 42.7 0.0 8.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase_fungal PF17667.1 KFM76901.1 - 3.2e-05 22.9 0.0 5.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM76901.1 - 0.0011 18.3 0.0 0.0029 16.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFM76901.1 - 0.055 12.4 0.0 0.12 11.3 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Gamma_PGA_hydro PF05908.11 KFM76901.1 - 0.17 11.2 0.2 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Poly-gamma-glutamate hydrolase ABC1 PF03109.16 KFM76902.1 - 1.3e-34 118.9 0.0 2.6e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KFM76902.1 - 4.2e-05 23.0 0.5 0.00054 19.4 0.1 2.4 2 1 0 3 3 3 1 Protein kinase domain ScdA_N PF04405.14 KFM76902.1 - 0.00051 19.7 2.1 0.0023 17.6 0.0 2.7 3 0 0 3 3 3 1 Domain of Unknown function (DUF542) APH PF01636.23 KFM76902.1 - 0.067 13.1 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFM76902.1 - 0.082 12.5 0.2 0.82 9.2 0.1 2.5 3 0 0 3 3 3 0 RIO1 family DUF2655 PF10848.8 KFM76902.1 - 0.14 12.5 0.0 0.61 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2655) Neur_chan_memb PF02932.16 KFM76903.1 - 1.1e-21 78.0 6.9 1.3e-19 71.3 2.0 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region COX1 PF00115.20 KFM76903.1 - 0.015 14.2 0.2 0.015 14.2 0.2 1.5 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I Orf78 PF06024.12 KFM76903.1 - 0.038 14.3 0.1 2.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) F5_F8_type_C PF00754.25 KFM76905.1 - 2.2e-09 37.5 0.3 0.00077 19.6 0.0 2.5 2 1 0 2 2 2 2 F5/8 type C domain DUF3907 PF13047.6 KFM76905.1 - 0.12 12.3 0.1 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) F5_F8_type_C PF00754.25 KFM76906.1 - 2.5e-25 89.0 0.1 3.5e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain RCC1 PF00415.18 KFM76907.1 - 3e-34 117.4 1.4 5.9e-11 42.8 0.0 5.0 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM76907.1 - 1.3e-26 91.7 9.3 2.3e-09 36.8 0.0 4.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 KFM76910.1 - 5.7e-24 84.9 1.0 5.9e-24 84.8 1.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM76910.1 - 7.7e-20 71.3 1.4 8.2e-20 71.2 1.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM76910.1 - 0.00053 20.0 0.2 0.061 13.2 0.2 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM76910.1 - 0.059 12.1 0.1 0.072 11.8 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Tenui_N PF05733.11 KFM76910.1 - 0.092 12.3 0.1 0.13 11.8 0.1 1.4 1 1 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein Aminotran_4 PF01063.19 KFM76911.1 - 1.5e-28 100.2 0.0 1.9e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Forkhead PF00250.18 KFM76914.1 - 6.8e-28 96.8 0.1 9.5e-28 96.3 0.1 1.2 1 0 0 1 1 1 1 Forkhead domain CwfJ_C_1 PF04677.15 KFM76916.1 - 0.091 12.6 0.2 0.22 11.4 0.1 1.6 1 1 1 2 2 2 0 Protein similar to CwfJ C-terminus 1 TED_complement PF07678.14 KFM76917.1 - 1.1e-49 169.1 0.6 3.7e-49 167.5 0.6 1.9 1 1 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 KFM76917.1 - 9e-29 100.0 0.2 3.4e-28 98.2 0.2 2.1 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain NTR PF01759.21 KFM76917.1 - 1e-16 60.7 0.2 2.4e-16 59.5 0.2 1.7 1 0 0 1 1 1 1 UNC-6/NTR/C345C module SQHop_cyclase_C PF13243.6 KFM76917.1 - 0.00016 20.9 0.1 0.0031 16.7 0.0 2.4 3 0 0 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFM76917.1 - 0.14 11.2 0.1 8.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KFM76917.1 - 0.19 11.5 3.6 2.4 8.0 0.0 3.0 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat IGR PF09597.10 KFM76918.1 - 0.071 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 IGR protein motif HTH_Tnp_Tc3_2 PF01498.18 KFM76919.1 - 4e-16 59.0 3.4 5.2e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76919.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76919.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76919.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76919.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RVT_1 PF00078.27 KFM76920.1 - 1e-40 139.7 0.0 2.2e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KFM76920.1 - 1.4e-21 76.6 0.3 6.2e-21 74.5 0.3 2.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KFM76920.1 - 1.3e-13 51.4 0.1 3.5e-13 50.0 0.1 1.8 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM76920.1 - 1.3e-05 25.0 0.1 2.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Exo_endo_phos PF03372.23 KFM76920.1 - 0.00031 20.3 0.5 0.00066 19.3 0.5 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family KxDL PF10241.9 KFM76920.1 - 0.11 12.8 1.1 0.44 10.9 1.1 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein zf-CCHC_4 PF14392.6 KFM76920.1 - 0.13 12.0 0.9 0.32 10.8 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KFM76920.1 - 0.53 10.5 7.3 0.16 12.1 2.5 2.5 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KFM76920.1 - 0.66 9.9 2.9 7 6.6 0.1 2.8 2 0 0 2 2 2 0 Zinc knuckle DDE_3 PF13358.6 KFM76921.1 - 3.4e-14 52.8 0.0 1.6e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76921.1 - 2.2e-08 34.2 0.2 6e-07 29.6 0.4 2.3 2 0 0 2 2 2 1 Transposase Carb_anhydrase PF00194.21 KFM76922.1 - 6e-23 81.7 0.1 7.1e-23 81.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Glyco_hydro_39 PF01229.17 KFM76922.1 - 0.077 11.6 0.0 0.088 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 DUF2976 PF11190.8 KFM76923.1 - 0.00032 20.5 5.2 0.12 12.2 0.2 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF2976) MTABC_N PF16185.5 KFM76923.1 - 0.26 10.8 7.8 0.4 10.1 7.9 1.4 1 1 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Serpentine_r_xa PF03383.15 KFM76923.1 - 0.84 9.6 8.5 0.13 12.2 3.2 2.1 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa zf-H2C2_2 PF13465.6 KFM76924.1 - 4.1e-124 400.0 113.2 3.5e-09 36.7 1.2 18.1 18 0 0 18 18 18 17 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76924.1 - 4.8e-87 281.9 142.7 1.6e-06 28.2 1.2 17.1 17 0 0 17 17 17 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76924.1 - 8.6e-62 200.4 135.1 0.00041 21.0 0.8 17.1 17 0 0 17 17 17 17 C2H2-type zinc finger zf-met PF12874.7 KFM76924.1 - 2.9e-51 170.5 124.8 0.00013 22.2 1.1 17.2 17 0 0 17 17 17 15 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM76924.1 - 5.4e-35 118.7 111.1 0.00025 20.9 0.4 17.4 17 0 0 17 17 17 15 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM76924.1 - 9.7e-27 92.7 85.6 0.0096 16.2 0.3 16.8 15 2 2 17 17 17 11 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM76924.1 - 7.1e-24 83.2 78.8 0.059 13.1 0.1 17.3 17 0 0 17 17 17 9 C2H2-type zinc-finger domain zf-DBF PF07535.12 KFM76924.1 - 3.3e-08 33.5 61.1 11 6.3 0.0 15.3 16 0 0 16 16 15 0 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM76924.1 - 4e-08 33.3 69.9 0.057 13.5 6.6 7.7 1 1 9 10 10 10 9 Putative ribonucleoprotein zinc-finger pf C4 type BolA PF01722.18 KFM76924.1 - 6.2e-08 32.8 24.4 1.5 9.2 0.1 9.6 1 1 8 10 10 10 1 BolA-like protein zf-C2H2_9 PF16293.5 KFM76924.1 - 2.5e-06 27.2 73.6 1.3 8.9 0.2 16.0 3 2 14 17 17 17 4 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM76924.1 - 7.6e-06 25.9 53.8 9.1 6.4 0.1 15.1 14 2 3 17 17 16 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 KFM76924.1 - 0.00029 21.1 108.2 1.2 9.6 0.3 15.9 1 1 15 16 16 16 3 C2H2 type zinc-finger (2 copies) Complex1_49kDa PF00346.19 KFM76924.1 - 0.00038 19.7 6.8 0.93 8.5 0.0 5.3 1 1 4 6 6 6 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Tox-HNH-HHH PF15637.6 KFM76924.1 - 0.00042 20.4 2.9 1.5 9.0 0.0 5.6 1 1 2 6 6 6 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-MYST PF17772.1 KFM76924.1 - 0.00098 18.7 81.1 2.3 7.9 0.5 15.9 6 5 11 17 17 17 4 MYST family zinc finger domain ADK_lid PF05191.14 KFM76924.1 - 0.0063 16.5 62.7 0.41 10.7 1.7 10.3 7 2 4 11 11 11 3 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM76924.1 - 0.007 17.1 70.0 1.8 9.4 8.1 8.6 2 1 6 8 8 8 2 zinc-ribbon family zf-C2H2_3rep PF18868.1 KFM76924.1 - 0.011 16.4 55.7 0.82 10.4 0.1 12.4 6 4 2 11 11 11 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 KFM76924.1 - 0.012 15.5 70.5 0.6 10.1 0.1 15.1 16 0 0 16 16 15 0 zinc-finger of a C2HC-type DUF1493 PF07377.12 KFM76924.1 - 0.017 15.6 1.6 58 4.2 0.1 5.1 3 2 2 6 6 4 0 Protein of unknown function (DUF1493) Yop-YscD_ppl PF16693.5 KFM76924.1 - 0.021 14.3 0.0 0.65 9.4 0.0 3.0 2 2 1 3 3 3 0 Inner membrane component of T3SS, periplasmic domain Lipoprotein_3 PF00938.17 KFM76924.1 - 0.033 14.4 0.5 51 4.2 0.0 5.4 5 2 2 8 8 8 0 Lipoprotein DUF5105 PF17118.5 KFM76924.1 - 0.033 14.0 0.0 1.3 8.8 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF5105) OSTMP1 PF09777.9 KFM76924.1 - 0.035 13.5 50.7 0.61 9.4 14.0 5.7 1 1 5 6 6 6 0 Osteopetrosis-associated transmembrane protein 1 precursor C1_1 PF00130.22 KFM76924.1 - 0.056 13.3 86.8 4.5 7.2 3.3 14.1 3 3 12 15 15 15 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.15 KFM76924.1 - 0.22 11.6 111.2 1.2 9.2 1.8 16.4 1 1 16 17 17 17 0 BED zinc finger GAGA PF09237.11 KFM76924.1 - 0.29 11.0 38.8 6.1 6.7 0.3 10.7 2 1 12 15 15 14 0 GAGA factor DUF2256 PF10013.9 KFM76924.1 - 0.32 11.1 73.1 6.2 7.0 0.1 16.3 17 0 0 17 17 17 0 Uncharacterized protein conserved in bacteria (DUF2256) IGPD PF00475.18 KFM76924.1 - 0.38 11.0 13.8 18 5.6 0.1 6.1 5 1 1 7 7 7 0 Imidazoleglycerol-phosphate dehydratase LPD24 PF18839.1 KFM76924.1 - 4.2 7.7 16.1 1.2 9.4 0.2 6.3 7 2 2 10 10 6 0 Large polyvalent protein associated domain 24 zf-RING_UBOX PF13445.6 KFM76924.1 - 5.5 7.1 39.1 83 3.3 0.4 13.5 14 3 2 16 16 16 0 RING-type zinc-finger C1_4 PF07975.12 KFM76924.1 - 9.6 6.5 81.4 1.5 9.2 1.7 10.8 2 2 11 13 13 13 0 TFIIH C1-like domain DDE_3 PF13358.6 KFM76925.1 - 2.4e-16 59.8 0.1 3.1e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76925.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase CNPase PF05881.12 KFM76926.1 - 3.1e-11 43.3 0.1 4.2e-10 39.6 0.1 2.1 1 1 0 1 1 1 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Acetyltransf_13 PF13880.6 KFM76928.1 - 1.4e-28 98.7 0.0 2.2e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 KFM76928.1 - 0.00013 22.3 0.0 0.00029 21.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM76928.1 - 0.00018 21.7 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-C2H2_3 PF13878.6 KFM76928.1 - 0.0011 18.8 1.7 0.0031 17.3 0.3 2.2 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO DUF3565 PF12088.8 KFM76928.1 - 0.038 14.0 0.7 0.07 13.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) A_deamin PF02137.18 KFM76929.1 - 6.3e-51 173.8 0.2 7e-51 173.6 0.2 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain A_deamin PF02137.18 KFM76930.1 - 0.0002 20.9 0.6 0.00027 20.5 0.6 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Gram_pos_anchor PF00746.21 KFM76930.1 - 0.052 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif CHCH PF06747.13 KFM76931.1 - 4.6e-08 33.0 2.6 8.8e-08 32.1 2.6 1.5 1 0 0 1 1 1 1 CHCH domain PfkB PF00294.24 KFM76931.1 - 0.049 12.9 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Cmc1 PF08583.10 KFM76931.1 - 0.27 11.3 3.3 2 8.5 3.9 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like PX PF00787.24 KFM76932.1 - 1.3e-18 67.0 0.0 4.2e-18 65.4 0.0 1.9 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 KFM76932.1 - 1.7e-08 34.2 0.0 6.6e-07 29.0 0.0 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM76932.1 - 1.4e-07 31.1 0.0 5.5e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase SMN PF06003.12 KFM76932.1 - 0.42 9.8 9.6 0.73 9.0 9.6 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) YbaJ PF10757.9 KFM76933.1 - 0.016 15.7 0.8 0.04 14.4 0.2 1.8 1 1 1 2 2 2 0 Biofilm formation regulator YbaJ HHH PF00633.23 KFM76935.1 - 0.00024 20.8 0.4 0.00076 19.2 0.2 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KFM76935.1 - 0.0037 17.8 0.0 0.0072 16.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain p25-alpha PF05517.12 KFM76935.1 - 0.12 12.5 0.0 1 9.5 0.0 1.9 2 0 0 2 2 2 0 p25-alpha HTH_Tnp_Tc3_2 PF01498.18 KFM76937.1 - 4.8e-16 58.8 3.5 5.5e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76937.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76937.1 - 2e-07 30.7 1.2 6.8e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76937.1 - 0.0026 17.5 0.6 0.0073 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76937.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM76938.1 - 2e-16 60.0 2.2 4.1e-16 59.0 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76938.1 - 8.5e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.22 KFM76940.1 - 3.5e-16 58.8 0.0 5.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM76940.1 - 1.7e-05 24.4 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFM76940.1 - 0.041 14.1 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain Zip PF02535.22 KFM76941.1 - 1.5e-23 83.6 4.2 1.6e-23 83.5 4.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Acyl_transf_3 PF01757.22 KFM76941.1 - 0.01 15.0 0.3 0.013 14.6 0.3 1.3 1 0 0 1 1 1 1 Acyltransferase family RNA_pol_Rpb2_6 PF00562.28 KFM76942.1 - 7.3e-128 426.9 0.1 1.1e-127 426.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFM76942.1 - 4.2e-68 228.9 0.0 5.9e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFM76942.1 - 2.8e-55 186.9 0.1 8.2e-55 185.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KFM76942.1 - 2.8e-34 117.4 0.7 1e-33 115.6 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KFM76942.1 - 7.6e-25 86.9 0.0 1.9e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KFM76942.1 - 2.3e-24 85.5 1.1 5.6e-24 84.2 1.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KFM76942.1 - 7.1e-20 71.3 0.6 1.7e-19 70.1 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 TTKRSYEDQ PF10212.9 KFM76943.1 - 7.6e-74 249.6 30.1 5.9e-49 167.5 10.8 3.4 2 2 1 3 3 3 2 Predicted coiled-coil domain-containing protein KLRAQ PF10205.9 KFM76943.1 - 7.2e-26 90.4 9.0 7.2e-26 90.4 9.0 5.1 3 2 2 5 5 5 1 Predicted coiled-coil domain-containing protein Tropomyosin_1 PF12718.7 KFM76943.1 - 0.0063 16.7 3.7 0.0063 16.7 3.7 5.0 3 2 1 4 4 4 1 Tropomyosin like DUF3416 PF11896.8 KFM76943.1 - 1.9 8.7 4.0 0.67 10.2 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) DASH_Dam1 PF08653.10 KFM76943.1 - 2.7 7.9 8.5 0.35 10.7 0.5 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 WD40 PF00400.32 KFM76944.1 - 8.7e-14 51.7 2.2 6e-05 23.7 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.7 KFM76944.1 - 1.5e-13 50.4 4.0 1.5e-13 50.4 1.6 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFM76944.1 - 4.6e-09 35.9 1.4 4.6e-09 35.9 1.4 3.0 3 0 0 3 3 3 1 F-box domain Ge1_WD40 PF16529.5 KFM76944.1 - 0.047 12.6 0.0 0.096 11.6 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KFM76944.1 - 0.051 13.9 0.2 0.35 11.2 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Claudin_2 PF13903.6 KFM76945.1 - 1.9e-30 106.1 3.8 2.3e-30 105.8 3.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 KFM76945.1 - 3.5e-08 33.6 3.5 7.2e-08 32.5 3.5 1.4 1 1 0 1 1 1 1 Tight junction protein, Claudin-like L_HMGIC_fpl PF10242.9 KFM76945.1 - 1.1e-07 32.2 3.7 1.4e-07 31.9 2.7 1.6 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 KFM76945.1 - 3.2e-07 30.4 3.3 0.0051 16.7 1.0 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DDE_3 PF13358.6 KFM76946.1 - 8.6e-05 22.3 0.0 9.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase_Tyr PF07714.17 KFM76947.1 - 0.0027 17.0 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM76947.1 - 0.0051 16.2 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Vps51 PF08700.11 KFM76948.1 - 3.9e-16 58.9 3.4 2.2e-15 56.5 3.4 2.3 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KFM76948.1 - 0.00026 19.8 3.8 0.00068 18.4 3.8 1.7 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 KFM76948.1 - 0.0029 17.8 3.3 0.011 15.9 1.1 2.9 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF1241 PF06840.11 KFM76948.1 - 0.0062 16.2 5.7 0.01 15.5 1.4 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1241) KxDL PF10241.9 KFM76948.1 - 2.5 8.4 8.0 0.4 11.0 1.2 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF3958 PF13125.6 KFM76948.1 - 2.9 8.2 8.0 0.26 11.5 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Snapin_Pallidin PF14712.6 KFM76948.1 - 4.7 7.7 11.9 0.26 11.7 4.7 2.8 3 0 0 3 3 3 0 Snapin/Pallidin ApoLp-III PF07464.11 KFM76948.1 - 8.1 6.5 7.6 3.5 7.7 0.7 3.6 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) UTP15_C PF09384.10 KFM76949.1 - 3.7e-42 143.5 0.1 1.3e-41 141.7 0.0 1.8 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.32 KFM76949.1 - 1.5e-22 79.4 4.3 7.8e-05 23.4 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM76949.1 - 5e-13 49.2 0.1 0.0004 20.6 0.0 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Aldo_ket_red PF00248.21 KFM76949.1 - 0.0014 17.9 0.1 0.0056 15.9 0.0 1.8 2 0 0 2 2 2 1 Aldo/keto reductase family Cytochrom_D1 PF02239.16 KFM76949.1 - 0.0024 16.4 0.6 0.16 10.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain p450 PF00067.22 KFM76951.1 - 1.3e-17 63.7 0.0 1.5e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-H2C2_2 PF13465.6 KFM76952.1 - 4.3e-54 178.7 49.0 4.3e-08 33.2 0.3 9.9 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM76952.1 - 2.4e-37 125.3 75.9 3.3e-05 24.1 0.8 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM76952.1 - 6.2e-24 82.6 71.7 0.00075 20.1 1.0 9.1 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM76952.1 - 3.5e-20 71.5 54.9 0.00023 21.0 1.4 8.7 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.7 KFM76952.1 - 3e-13 49.7 62.3 0.0082 16.5 1.0 9.5 9 0 0 9 9 9 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM76952.1 - 2.7e-09 37.1 46.7 0.15 12.3 1.6 9.0 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM76952.1 - 1.3e-05 24.9 22.7 0.94 9.3 0.2 7.6 1 1 7 8 8 8 1 GAGA factor BolA PF01722.18 KFM76952.1 - 4.5e-05 23.6 14.6 0.02 15.1 0.2 5.0 1 1 2 5 5 5 2 BolA-like protein zf-Sec23_Sec24 PF04810.15 KFM76952.1 - 8.8e-05 22.5 21.5 0.7 10.0 0.1 7.2 6 1 2 8 8 8 2 Sec23/Sec24 zinc finger DZR PF12773.7 KFM76952.1 - 0.00061 19.8 22.2 0.8 9.8 4.1 4.8 1 1 2 3 3 3 1 Double zinc ribbon zf-MYST PF17772.1 KFM76952.1 - 0.0011 18.5 33.2 0.23 11.1 0.1 7.1 4 2 4 8 8 8 3 MYST family zinc finger domain ADK_lid PF05191.14 KFM76952.1 - 0.002 18.0 28.9 0.49 10.4 1.1 5.7 3 2 2 5 5 5 3 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KFM76952.1 - 0.0084 15.8 55.6 0.088 12.6 0.8 9.0 9 0 0 9 9 9 2 C2H2-type zinc-finger domain C1_1 PF00130.22 KFM76952.1 - 0.0088 15.9 35.8 0.92 9.4 3.0 6.8 2 2 5 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1758 PF05585.12 KFM76952.1 - 0.013 15.2 0.0 0.042 13.6 0.0 1.8 2 1 0 2 2 2 0 Putative peptidase (DUF1758) zf-C2H2_2 PF12756.7 KFM76952.1 - 0.032 14.5 50.8 0.94 9.9 0.9 7.6 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM76952.1 - 0.036 14.2 25.3 0.1 12.7 3.8 3.8 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM76952.1 - 0.061 13.5 26.1 25 5.1 0.1 7.6 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_8 PF15909.5 KFM76952.1 - 0.11 12.8 33.1 0.25 11.7 3.7 4.2 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf-FPG_IleRS PF06827.14 KFM76952.1 - 0.29 11.0 23.1 30 4.6 0.1 7.5 8 0 0 8 8 8 0 Zinc finger found in FPG and IleRS zf_UBZ PF18439.1 KFM76952.1 - 1 9.0 30.6 8.1 6.1 0.1 7.1 8 0 0 8 8 7 0 Ubiquitin-Binding Zinc Finger Scramblase PF03803.15 KFM76952.1 - 1.1 8.5 5.5 3.6 6.8 0.3 2.2 1 1 2 3 3 3 0 Scramblase zinc_ribbon_15 PF17032.5 KFM76952.1 - 1.3 9.9 25.5 19 6.1 5.2 4.2 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM76952.1 - 1.6 8.7 36.0 7.2 6.5 0.1 7.6 4 3 5 9 9 9 0 C2H2 type zinc-finger (1 copy) YceD PF02620.17 KFM76952.1 - 1.6 8.9 11.9 21 5.3 1.5 5.4 1 1 5 6 6 6 0 Large ribosomal RNA subunit accumulation protein YceD FYDLN_acid PF09538.10 KFM76952.1 - 2 9.1 15.3 47 4.7 0.0 6.3 1 1 7 8 8 8 0 Protein of unknown function (FYDLN_acid) DUF3268 PF11672.8 KFM76952.1 - 4 7.8 19.6 6.5 7.1 0.9 4.1 2 2 1 4 4 4 0 zinc-finger-containing domain Prok-RING_2 PF14445.6 KFM76952.1 - 5.9 7.1 21.4 53 4.1 0.0 6.9 7 1 1 8 8 7 0 Prokaryotic RING finger family 2 Zn-ribbon_8 PF09723.10 KFM76952.1 - 5.9 7.1 22.1 2.6 8.3 1.1 5.0 3 2 3 6 6 6 0 Zinc ribbon domain Zf_RING PF16744.5 KFM76952.1 - 6.6 6.9 35.5 0.77 9.9 0.8 7.1 1 1 6 7 7 7 0 KIAA1045 RING finger zf-H2C2_2 PF13465.6 KFM76953.1 - 0.064 13.7 3.5 0.41 11.2 3.5 2.1 1 1 0 1 1 1 0 Zinc-finger double domain LysM PF01476.20 KFM76953.1 - 0.11 12.5 0.1 0.85 9.7 0.1 2.0 2 0 0 2 2 2 0 LysM domain HTH_Tnp_Tc3_2 PF01498.18 KFM76954.1 - 5.1e-16 58.7 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76954.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76954.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76954.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76954.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain XRCC1_N PF01834.16 KFM76955.1 - 2.5e-12 47.0 2.3 3.7e-12 46.5 0.8 2.0 2 0 0 2 2 2 1 XRCC1 N terminal domain RNF220 PF15926.5 KFM76955.1 - 0.016 14.8 0.9 0.11 12.2 0.1 2.4 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 zf-Di19 PF05605.12 KFM76955.1 - 0.038 14.3 0.4 7.5 6.9 0.1 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KFM76955.1 - 0.16 12.4 4.1 1.6 9.3 0.5 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain HTH_Tnp_Tc3_2 PF01498.18 KFM76956.1 - 2.6e-16 59.6 2.2 4.8e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76956.1 - 1.1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1690 PF07956.11 KFM76957.1 - 2.5e-05 24.7 13.1 0.00022 21.7 13.1 2.2 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) IMPa_helical PF18642.1 KFM76957.1 - 0.0022 18.4 1.2 0.0055 17.1 0.5 1.9 2 0 0 2 2 2 1 Immunomodulating metalloprotease helical domain Bul1_N PF04425.12 KFM76957.1 - 0.0087 14.9 1.1 0.01 14.6 1.1 1.1 1 0 0 1 1 1 1 Bul1 N terminus Spectrin PF00435.21 KFM76957.1 - 0.011 16.2 1.0 0.019 15.5 0.4 1.6 2 0 0 2 2 2 0 Spectrin repeat AAA_32 PF13654.6 KFM76957.1 - 0.063 12.1 2.6 0.07 11.9 2.6 1.1 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.6 KFM76957.1 - 0.07 12.1 0.7 0.095 11.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3811 PF11656.8 KFM76957.1 - 0.081 13.3 2.3 0.25 11.8 0.1 2.4 2 1 1 3 3 3 0 YjbD family (DUF3811) DUF370 PF04025.12 KFM76957.1 - 0.11 12.6 0.5 1.2 9.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF370) Jnk-SapK_ap_N PF09744.9 KFM76957.1 - 0.35 11.1 8.1 0.2 11.8 6.0 1.5 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF737 PF05300.11 KFM76957.1 - 0.79 10.0 14.8 7.7 6.8 14.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF737) THAP PF05485.12 KFM76958.1 - 1.5e-12 48.3 0.1 4.7e-12 46.7 0.1 1.9 1 0 0 1 1 1 1 THAP domain MULE PF10551.9 KFM76958.1 - 1.4e-05 25.4 0.1 0.00046 20.5 0.0 3.2 3 0 0 3 3 3 1 MULE transposase domain SWIM PF04434.17 KFM76958.1 - 0.013 15.2 4.3 0.033 13.9 4.3 1.7 1 0 0 1 1 1 0 SWIM zinc finger IDEAL PF08858.10 KFM76958.1 - 0.11 12.2 0.2 0.47 10.2 0.3 2.0 2 0 0 2 2 2 0 IDEAL domain tRNA_bind PF01588.20 KFM76959.1 - 1.4e-05 25.1 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain DNA_mis_repair PF01119.19 KFM76960.1 - 2.2e-22 79.0 0.1 5.9e-22 77.6 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFM76960.1 - 1.6e-15 57.2 0.0 4.4e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFM76960.1 - 5.8e-06 26.8 0.0 1.5e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lantibiotic_a PF14867.6 KFM76961.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Lantibiotic alpha MutL_C PF08676.11 KFM76962.1 - 7.7e-12 45.2 0.0 9.2e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DUF4238 PF14022.6 KFM76962.1 - 0.012 15.1 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Patatin PF01734.22 KFM76963.1 - 3.2e-17 63.4 0.1 2.8e-16 60.3 0.1 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase DHC_N2 PF08393.13 KFM76964.1 - 4.4e-13 49.1 1.2 4.7e-13 49.0 1.2 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Mistic PF11458.8 KFM76964.1 - 0.047 13.7 0.2 0.069 13.1 0.2 1.3 1 0 0 1 1 1 0 Membrane-integrating protein Mistic AAA_5 PF07728.14 KFM76965.1 - 2.5e-08 34.0 0.0 2.9e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KFM76965.1 - 0.0022 18.5 0.0 0.0026 18.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TrwB_AAD_bind PF10412.9 KFM76965.1 - 0.0037 16.2 0.7 0.016 14.2 0.1 1.9 1 1 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 KFM76965.1 - 0.0039 16.7 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 KFM76965.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFM76965.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF3363 PF11843.8 KFM76965.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) AAA PF00004.29 KFM76965.1 - 0.13 12.7 0.0 0.15 12.5 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM76965.1 - 0.15 12.3 0.0 0.21 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFM76965.1 - 0.18 12.1 0.1 0.19 12.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM76965.1 - 0.18 12.1 0.0 0.33 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFM76966.1 - 8.9e-40 136.1 0.1 1.2e-39 135.8 0.1 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 KFM76966.1 - 5.7e-16 58.8 0.0 1.2e-15 57.7 0.0 1.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KFM76966.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KFM76966.1 - 0.061 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM76966.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM76966.1 - 0.16 12.3 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_lid_1 PF17857.1 KFM76967.1 - 9e-18 64.3 0.0 1.3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 KFM76967.1 - 7e-14 51.8 0.0 9.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_8 PF12780.7 KFM76968.1 - 7.6e-28 97.5 0.1 8.4e-28 97.4 0.1 1.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 KFM76968.1 - 0.0021 18.1 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_8 PF12780.7 KFM76969.1 - 2.8e-09 36.7 0.1 2.9e-09 36.6 0.1 1.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 TRAP-delta PF05404.12 KFM76969.1 - 0.016 14.8 0.1 0.017 14.7 0.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) Rep_fac_C PF08542.11 KFM76969.1 - 0.087 13.2 0.0 0.095 13.1 0.0 1.0 1 0 0 1 1 1 0 Replication factor C C-terminal domain MT PF12777.7 KFM76970.1 - 2.5e-08 33.3 0.0 2.8e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 KFM76971.1 - 9.9e-60 201.4 0.0 1.4e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 ATP-binding dynein motor region MT PF12777.7 KFM76971.1 - 2.2e-09 36.8 0.0 3.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 KFM76972.1 - 3.9e-11 42.5 2.2 6.1e-11 41.9 2.2 1.3 1 0 0 1 1 1 1 ATP-binding dynein motor region DUF4533 PF15047.6 KFM76972.1 - 0.022 14.3 0.9 0.13 11.8 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4533) Chitin_bind_4 PF00379.23 KFM76973.1 - 3.6e-11 43.4 4.6 3.6e-11 43.4 4.6 1.8 2 0 0 2 2 2 1 Insect cuticle protein AAA_13 PF13166.6 KFM76974.1 - 0.097 11.3 1.8 0.11 11.1 1.8 1.0 1 0 0 1 1 1 0 AAA domain CUB PF00431.20 KFM76975.1 - 3.3e-06 27.4 0.0 4.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 CUB domain HTH_Tnp_Tc3_2 PF01498.18 KFM76976.1 - 2.4e-16 59.8 2.2 6.8e-16 58.3 2.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76976.1 - 1.6e-13 50.7 0.0 2.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76976.1 - 3.6e-07 29.9 1.6 8.2e-07 28.7 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76976.1 - 0.0033 17.2 0.5 0.0088 15.8 0.5 1.8 1 0 0 1 1 1 1 Homeodomain-like domain zf-BED PF02892.15 KFM76976.1 - 0.012 15.7 0.1 0.049 13.7 0.1 2.1 1 0 0 1 1 1 0 BED zinc finger HTH_32 PF13565.6 KFM76976.1 - 3 8.5 15.6 0.15 12.7 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.6 KFM76977.1 - 6.2e-11 42.2 0.0 8.1e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76978.1 - 2.9e-16 59.4 2.8 5.1e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM76978.1 - 1.1e-12 48.0 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM76978.1 - 2.7e-07 30.2 0.2 6.5e-07 29.0 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM76978.1 - 0.0024 17.6 0.6 0.0069 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM76978.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM76979.1 - 8.5e-16 58.0 6.5 1.7e-15 57.0 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM76979.1 - 9.1e-16 57.9 0.0 6.8e-15 55.1 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM76979.1 - 0.00081 20.0 1.5 0.00081 20.0 1.5 2.8 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM76979.1 - 0.0031 17.2 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM76979.1 - 0.017 15.3 0.1 0.072 13.2 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM76979.1 - 0.039 14.0 0.4 0.039 14.0 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 KFM76979.1 - 0.14 12.3 0.3 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Histone_H2A_C PF16211.5 KFM76980.1 - 1.7e-21 75.7 1.9 3.3e-21 74.7 1.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM76980.1 - 2.9e-15 56.8 0.0 3.5e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM76980.1 - 8.4e-06 26.0 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KFM76981.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFM76981.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFM76981.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFM76981.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM76981.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFM76981.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFM76981.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFM76981.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TMEM173 PF15009.6 KFM76982.1 - 7.8e-35 120.4 4.4 8.8e-35 120.3 4.4 1.1 1 0 0 1 1 1 1 Transmembrane protein 173 GCP_C_terminal PF04130.13 KFM76983.1 - 7.3e-79 265.4 7.9 1.1e-78 264.8 7.9 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFM76983.1 - 3.2e-74 250.3 0.4 6.1e-74 249.4 0.4 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal KOW PF00467.29 KFM76984.1 - 0.044 13.8 0.8 0.062 13.3 0.8 1.2 1 0 0 1 1 1 0 KOW motif Pkinase PF00069.25 KFM76985.1 - 0.0042 16.5 0.0 0.0045 16.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain PTEN_C2 PF10409.9 KFM76988.1 - 1.7e-22 79.6 0.0 2.8e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.31 KFM76988.1 - 5.8e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DSPc PF00782.20 KFM76988.1 - 0.0019 18.0 0.3 0.0036 17.1 0.3 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Phenyl_P_gamma PF09662.10 KFM76988.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) DDE_3 PF13358.6 KFM76989.1 - 2.8e-16 59.6 0.1 3.2e-15 56.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM76989.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase Rhomboid PF01694.22 KFM76991.1 - 1.5e-07 31.5 1.7 1.9e-07 31.2 0.2 1.7 1 1 1 2 2 2 1 Rhomboid family Frag1 PF10277.9 KFM76991.1 - 0.012 15.2 0.3 0.013 15.0 0.3 1.0 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF202 PF02656.15 KFM76991.1 - 0.33 11.4 2.8 0.34 11.4 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Njmu-R1 PF15053.6 KFM76992.1 - 8.9e-51 173.0 1.1 1e-50 172.8 1.1 1.0 1 0 0 1 1 1 1 Mjmu-R1-like protein family F_actin_bind PF08919.10 KFM76993.1 - 0.017 15.2 0.7 0.038 14.1 0.7 1.7 1 0 0 1 1 1 0 F-actin binding Mt_ATP-synt_B PF05405.14 KFM76993.1 - 0.051 13.2 2.0 0.29 10.7 0.1 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SNAPc_SNAP43 PF09808.9 KFM76994.1 - 8e-08 32.4 0.0 8e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 SNAPc_SNAP43 PF09808.9 KFM76995.1 - 8.9e-11 42.1 0.5 9.3e-11 42.0 0.5 1.0 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 INSC_LBD PF16748.5 KFM76996.1 - 0.00057 19.3 0.0 0.0017 17.8 0.0 1.8 1 0 0 1 1 1 1 Inscuteable LGN-binding domain Arm PF00514.23 KFM76996.1 - 0.065 13.3 4.4 0.14 12.2 0.1 3.7 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat COG5 PF10392.9 KFM76996.1 - 0.078 13.1 4.5 0.078 13.1 1.8 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Pyr_redox_2 PF07992.14 KFM76997.1 - 3.2e-28 98.8 0.2 2.3e-13 50.0 0.2 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 KFM76997.1 - 1.5e-08 34.4 0.1 3e-07 30.2 0.0 2.7 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain DAO PF01266.24 KFM76997.1 - 0.00018 21.3 0.1 0.002 17.8 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFM76997.1 - 0.002 17.4 1.5 0.46 9.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFM76997.1 - 0.0022 18.0 0.0 0.5 10.3 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KFM76997.1 - 0.0049 16.0 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFM76997.1 - 0.012 15.8 0.3 0.044 14.0 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KFM76997.1 - 0.014 15.8 0.2 5.1 7.6 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KFM76997.1 - 0.015 14.4 0.4 0.86 8.6 0.3 2.4 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 KFM76997.1 - 0.025 13.7 0.2 3.5 6.7 0.0 2.2 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFM76997.1 - 0.039 14.5 1.1 4.3 8.0 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM76997.1 - 0.35 9.9 2.0 2.2 7.2 1.4 2.4 2 1 1 3 3 3 0 Glucose inhibited division protein A UCR_UQCRX_QCR9 PF05365.12 KFM76998.1 - 1e-25 89.4 0.8 1.1e-25 89.3 0.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-H2C2_2 PF13465.6 KFM77000.1 - 1e-47 158.5 45.5 7.7e-10 38.8 0.9 7.7 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM77000.1 - 2.4e-40 134.7 46.4 9e-06 25.9 0.5 7.2 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM77000.1 - 9.4e-27 91.4 44.5 0.0022 18.7 1.0 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 KFM77000.1 - 5.5e-21 74.3 39.2 0.0017 18.7 0.2 7.5 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM77000.1 - 1.9e-18 66.0 41.2 0.0059 16.6 0.9 7.9 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM77000.1 - 2.2e-15 56.5 30.9 0.03 14.6 0.0 7.8 7 1 1 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM77000.1 - 9.9e-10 38.0 28.9 0.0049 16.6 0.5 7.3 7 0 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM77000.1 - 5.2e-05 23.5 35.4 0.85 10.0 0.3 6.7 1 1 5 6 6 6 2 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.6 KFM77000.1 - 9.6e-05 22.2 28.7 0.52 10.2 1.1 7.1 4 2 2 6 6 6 3 HNH endonuclease zf-CHCC PF10276.9 KFM77000.1 - 0.00041 20.4 7.6 57 3.9 0.0 6.6 7 0 0 7 7 7 0 Zinc-finger domain TRAF6_Z2 PF18048.1 KFM77000.1 - 0.00056 19.9 23.4 2.1 8.5 0.1 7.3 7 0 0 7 7 7 2 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_9 PF16293.5 KFM77000.1 - 0.00058 19.7 17.3 18 5.3 0.1 7.0 2 2 5 7 7 7 0 C2H2 type zinc-finger (1 copy) C1_1 PF00130.22 KFM77000.1 - 0.00065 19.5 33.1 2.2 8.2 0.2 6.8 1 1 6 7 7 7 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KFM77000.1 - 0.00068 19.6 19.9 0.34 10.9 1.8 4.9 3 2 2 5 5 5 2 Adenylate kinase, active site lid GAGA PF09237.11 KFM77000.1 - 0.0029 17.4 13.8 6 6.8 0.0 5.9 1 1 6 7 7 7 0 GAGA factor zf-MYST PF17772.1 KFM77000.1 - 0.0031 17.1 19.0 3.2 7.4 0.1 6.5 4 2 3 7 7 7 1 MYST family zinc finger domain Tox-HNH-HHH PF15637.6 KFM77000.1 - 0.0031 17.6 0.6 19 5.5 0.0 3.7 1 1 3 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-RRPl_C4 PF17026.5 KFM77000.1 - 0.028 14.5 19.1 0.57 10.3 5.7 3.5 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_3rep PF18868.1 KFM77000.1 - 0.028 15.1 22.2 4.5 8.0 0.5 5.9 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF2256 PF10013.9 KFM77000.1 - 0.074 13.2 24.0 42 4.4 0.1 7.0 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) Ribosomal_S4e PF00900.20 KFM77000.1 - 0.077 12.9 7.4 0.23 11.4 0.3 3.4 2 2 1 3 3 3 0 Ribosomal family S4e zf-BED PF02892.15 KFM77000.1 - 0.08 13.0 44.1 1.1 9.3 3.8 7.1 2 2 5 7 7 7 0 BED zinc finger FYVE PF01363.21 KFM77000.1 - 0.12 12.5 30.5 1.5e+02 2.6 0.3 3.8 1 1 1 2 2 1 0 FYVE zinc finger zf-C2HC_2 PF13913.6 KFM77000.1 - 0.21 11.5 29.7 3.5 7.6 0.1 7.1 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM77000.1 - 0.24 12.2 22.9 3.2 8.6 2.9 3.9 1 1 4 5 5 5 0 zinc-ribbon family DUF3268 PF11672.8 KFM77000.1 - 0.26 11.6 12.8 1.9 8.9 0.1 3.8 2 1 1 4 4 4 0 zinc-finger-containing domain zf-DBF PF07535.12 KFM77000.1 - 0.61 10.2 20.5 16 5.7 0.1 6.1 6 1 1 7 7 7 0 DBF zinc finger FYDLN_acid PF09538.10 KFM77000.1 - 0.79 10.4 12.3 8.4 7.1 0.9 5.3 3 2 2 5 5 5 0 Protein of unknown function (FYDLN_acid) zf-Sec23_Sec24 PF04810.15 KFM77000.1 - 0.84 9.7 23.6 4.9 7.3 0.1 6.6 6 1 1 7 7 7 0 Sec23/Sec24 zinc finger zf_UBZ PF18439.1 KFM77000.1 - 1 9.0 24.8 10 5.8 0.1 7.0 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM77000.1 - 1.6 8.9 23.3 0.43 10.7 1.2 4.8 3 2 2 5 5 5 0 Zinc ribbon domain zf-UDP PF14569.6 KFM77000.1 - 1.9 8.7 22.3 3.1 8.0 5.2 4.9 1 1 2 4 4 4 0 Zinc-binding RING-finger zf-HIT PF04438.16 KFM77000.1 - 4 7.4 35.1 10 6.1 0.3 7.0 7 0 0 7 7 7 0 HIT zinc finger YyzF PF14116.6 KFM77000.1 - 5.5 7.1 21.4 7.3 6.7 0.2 6.3 7 0 0 7 7 7 0 YyzF-like protein C1_4 PF07975.12 KFM77000.1 - 7.9 6.8 26.2 1.1 9.5 2.0 4.8 1 1 6 7 7 7 0 TFIIH C1-like domain gag_pre-integrs PF13976.6 KFM77000.1 - 9.9 6.1 25.3 19 5.2 0.1 5.7 5 1 1 6 6 6 0 GAG-pre-integrase domain DDE_Tnp_1_7 PF13843.6 KFM77001.1 - 2.4e-83 280.4 3.8 2.4e-83 280.4 3.8 1.3 2 0 0 2 2 2 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM77001.1 - 0.00084 20.1 9.5 0.0019 19.0 9.5 1.6 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon DDE_Tnp_1 PF01609.21 KFM77001.1 - 0.0016 18.1 1.5 0.0016 18.1 1.5 2.0 2 1 0 2 2 2 1 Transposase DDE domain DUF4371 PF14291.6 KFM77003.1 - 4.1e-07 29.9 0.0 2.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4371) Pkinase PF00069.25 KFM77004.1 - 1.7e-65 221.0 0.0 3.1e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM77004.1 - 2.5e-34 118.8 0.0 4.1e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFM77004.1 - 4.7e-16 59.1 3.6 4.7e-16 59.1 3.6 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.6 KFM77004.1 - 2.6e-05 23.7 0.0 4.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM77004.1 - 4.8e-05 22.3 0.0 9.7e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM77004.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2760 PF10816.8 KFM77004.1 - 0.035 13.9 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) Peptidase_S48 PF03574.15 KFM77006.1 - 0.14 12.3 0.4 0.35 11.1 0.4 1.7 1 0 0 1 1 1 0 Peptidase family S48 zf-C2HC_2 PF13913.6 KFM77007.1 - 3e-17 62.0 18.7 1.1e-09 37.9 0.8 4.4 4 0 0 4 4 4 2 zinc-finger of a C2HC-type Sgf11 PF08209.11 KFM77007.1 - 2.6e-08 33.3 4.8 7e-05 22.3 0.1 3.7 3 0 0 3 3 3 2 Sgf11 (transcriptional regulation protein) zf_C2HC_14 PF18574.1 KFM77007.1 - 0.0003 20.5 2.0 0.0003 20.5 2.0 2.5 2 0 0 2 2 2 1 C2HC Zing finger domain DUF2318 PF10080.9 KFM77007.1 - 0.002 18.2 5.6 2 8.6 0.0 3.5 2 1 1 3 3 3 1 Predicted membrane protein (DUF2318) zf-RING_7 PF02591.15 KFM77007.1 - 0.0086 16.2 0.2 0.2 11.9 0.0 2.9 2 0 0 2 2 2 1 C4-type zinc ribbon domain zf-dskA_traR PF01258.17 KFM77007.1 - 0.083 12.8 3.6 2.9 7.9 0.0 3.0 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Zn-ribbon_8 PF09723.10 KFM77007.1 - 0.099 12.8 3.8 4.6 7.4 0.4 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-BED PF02892.15 KFM77007.1 - 0.28 11.3 3.4 16 5.6 0.6 2.9 2 0 0 2 2 2 0 BED zinc finger DZR PF12773.7 KFM77007.1 - 0.4 10.7 5.1 1.6 8.8 1.2 3.0 3 1 0 3 3 3 0 Double zinc ribbon zf_C2H2_13 PF18508.1 KFM77007.1 - 0.73 9.5 0.0 0.73 9.5 0.0 2.6 3 0 0 3 3 3 0 Zinc finger domain zf-C2H2 PF00096.26 KFM77007.1 - 0.9 10.1 14.1 0.36 11.4 0.5 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM77007.1 - 6.3 7.9 20.2 5.6 8.1 0.5 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger HTH_Tnp_Tc3_2 PF01498.18 KFM77008.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77008.1 - 7.2e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease LRR_8 PF13855.6 KFM77010.1 - 3.8e-43 145.1 99.4 1.8e-11 43.7 5.1 10.5 5 2 8 13 13 13 11 Leucine rich repeat LRR_4 PF12799.7 KFM77010.1 - 4.4e-22 77.8 71.0 7.6e-05 23.0 6.9 11.2 7 2 1 10 10 10 7 Leucine Rich repeats (2 copies) TIR PF01582.20 KFM77010.1 - 6.3e-19 68.4 0.6 1.6e-18 67.1 0.6 1.7 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFM77010.1 - 1.4e-14 54.7 0.1 2.9e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 KFM77010.1 - 6.2e-05 22.6 27.7 0.014 14.9 3.5 4.9 2 1 2 5 5 5 5 Leucine-rich repeat LRRNT PF01462.18 KFM77010.1 - 0.01 15.5 0.6 0.01 15.5 0.6 3.3 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFM77010.1 - 0.44 11.3 60.1 2.5 9.0 1.9 14.0 13 3 0 13 13 13 0 Leucine Rich Repeat LRR_6 PF13516.6 KFM77010.1 - 0.94 9.7 42.8 6.6 7.1 0.3 12.3 14 0 0 14 14 14 0 Leucine Rich repeat BTB_2 PF02214.22 KFM77011.1 - 2.5e-17 63.0 0.1 4.2e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain QVR PF17064.5 KFM77012.1 - 0.00065 19.9 5.6 0.0012 19.0 5.6 1.5 1 1 0 1 1 1 1 Sleepless protein Peptidase_M15_4 PF13539.6 KFM77012.1 - 1.5 9.4 5.7 11 6.6 0.4 2.3 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Synaptobrevin PF00957.21 KFM77013.1 - 1.4e-14 53.6 0.5 2.4e-14 52.9 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFM77013.1 - 1.6e-11 44.1 0.1 2.4e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain T3SS_basalb_I PF17001.5 KFM77013.1 - 0.066 13.8 0.2 0.093 13.3 0.2 1.3 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI zf-tcix PF14952.6 KFM77015.1 - 9.7e-22 76.3 5.3 2e-21 75.3 5.3 1.5 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding DUF2423 PF10338.9 KFM77015.1 - 0.069 13.4 1.6 0.24 11.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Mu-like_Com PF10122.9 KFM77015.1 - 0.09 12.2 2.5 0.19 11.2 2.5 1.5 1 0 0 1 1 1 0 Mu-like prophage protein Com DUF4371 PF14291.6 KFM77016.1 - 6.3e-06 26.0 0.9 1.5e-05 24.8 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM77016.1 - 0.0013 18.3 0.1 0.0026 17.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger C2H2-type GAGA PF09237.11 KFM77016.1 - 0.085 12.7 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 GAGA factor gag_pre-integrs PF13976.6 KFM77017.1 - 7.1e-08 32.2 1.8 8.3e-08 32.0 0.1 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.23 KFM77017.1 - 3.1e-07 30.2 11.8 0.00036 20.5 2.4 2.7 2 0 0 2 2 2 2 Zinc knuckle rve PF00665.26 KFM77017.1 - 5.6e-06 26.5 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 KFM77017.1 - 0.00022 20.9 0.4 0.00048 19.8 0.4 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 KFM77017.1 - 0.01 15.5 8.4 1.1 9.0 0.9 3.4 3 0 0 3 3 3 0 Zinc knuckle Pox_A21 PF05323.12 KFM77017.1 - 0.043 14.4 0.2 0.14 12.7 0.2 1.9 1 0 0 1 1 1 0 Poxvirus A21 Protein Vault_4 PF17796.1 KFM77017.1 - 0.17 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Major Vault Protein repeat domain DDE_1 PF03184.19 KFM77018.1 - 9.2e-30 103.6 0.3 1.4e-29 103.0 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM77018.1 - 3.2e-11 43.1 0.2 3.2e-11 43.1 0.2 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM77018.1 - 0.0062 16.3 0.0 0.073 12.8 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease LolA PF03548.15 KFM77018.1 - 0.051 13.3 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA DUF2149 PF09919.9 KFM77019.1 - 0.072 13.4 0.0 0.096 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) HTH_Tnp_Tc3_2 PF01498.18 KFM77020.1 - 4.9e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77020.1 - 1.3e-12 47.7 0.0 2.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77020.1 - 2.8e-07 30.2 1.6 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77020.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM77020.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain zf-C2H2_4 PF13894.6 KFM77022.1 - 4.8e-07 30.1 40.0 0.01 16.6 2.4 7.9 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM77022.1 - 0.0012 19.2 50.1 0.018 15.5 0.1 7.7 8 0 0 8 8 8 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM77022.1 - 0.0015 18.2 17.9 0.011 15.4 4.7 3.7 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFM77022.1 - 0.0082 16.5 1.0 0.0082 16.5 1.0 6.8 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM77022.1 - 0.019 15.2 38.4 1.5 9.2 0.9 7.5 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM77022.1 - 0.5 10.8 47.7 0.098 13.1 0.5 8.1 8 0 0 8 8 8 0 Zinc-finger of C2H2 type DER1 PF04511.15 KFM77024.1 - 0.018 15.0 0.3 0.019 14.9 0.3 1.1 1 0 0 1 1 1 0 Der1-like family Bap31 PF05529.12 KFM77024.1 - 0.036 13.9 0.0 0.036 13.9 0.0 1.0 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region DUF1394 PF07159.12 KFM77026.1 - 3.9e-48 164.3 1.0 4.3e-48 164.1 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.6 KFM77026.1 - 0.0089 14.6 0.0 0.0089 14.6 0.0 1.1 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal Elong_Iki1 PF10483.9 KFM77027.1 - 9.9e-10 38.4 2.3 1.5e-05 24.7 0.3 2.1 1 1 1 2 2 2 2 Elongator subunit Iki1 HTH_Tnp_Tc3_2 PF01498.18 KFM77029.1 - 1.2e-32 112.0 12.3 2.1e-16 59.9 2.7 2.7 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM77029.1 - 2.6e-16 59.7 0.0 1.1e-12 47.9 0.0 3.4 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_28 PF13518.6 KFM77029.1 - 3.7e-07 30.2 9.6 8.2e-05 22.6 0.2 3.7 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_38 PF13936.6 KFM77029.1 - 2e-06 27.4 0.2 2e-06 27.4 0.2 3.7 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_23 PF13384.6 KFM77029.1 - 2.8e-06 26.9 6.7 0.022 14.5 0.5 3.7 3 0 0 3 3 3 2 Homeodomain-like domain CENP-B_N PF04218.13 KFM77029.1 - 0.012 15.3 0.3 0.19 11.4 0.0 2.6 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 KFM77029.1 - 0.14 12.2 0.2 18 5.5 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 KFM77029.1 - 0.2 11.1 0.0 0.2 11.1 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 KFM77029.1 - 7.1 7.3 32.9 0.047 14.3 2.3 4.6 4 1 1 5 5 5 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM77031.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77031.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77031.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77031.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM77031.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM77032.1 - 2.2e-16 59.8 2.2 5.5e-16 58.6 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77032.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77032.1 - 1.3e-06 28.1 0.4 7.2e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77032.1 - 0.0051 16.6 0.2 0.015 15.1 0.2 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM77032.1 - 6.1 7.5 15.1 0.12 13.0 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM77033.1 - 4.2e-18 65.4 0.2 4.2e-18 65.4 0.2 1.5 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KFM77033.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM77033.1 - 0.21 12.2 3.1 0.11 13.1 1.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain WD40 PF00400.32 KFM77034.1 - 5.4e-07 30.2 0.4 0.019 15.8 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM77034.1 - 0.0023 18.2 0.0 0.93 9.8 0.0 3.0 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ras PF00071.22 KFM77036.1 - 7.7e-56 188.2 0.0 8.9e-56 188.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM77036.1 - 1.1e-22 80.5 0.0 1.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM77036.1 - 4.1e-08 32.9 0.0 5.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 KFM77036.1 - 0.028 14.1 0.2 0.73 9.6 0.0 2.8 2 2 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4817 PF16087.5 KFM77037.1 - 2.3e-07 30.5 0.0 4.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_Tnp_Tc3_2 PF01498.18 KFM77037.1 - 2.7e-06 27.5 0.0 4.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM77037.1 - 9.7e-06 26.1 2.8 1e-05 26.0 1.9 1.6 1 1 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 KFM77037.1 - 9.5e-05 21.9 0.1 0.00017 21.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 KFM77037.1 - 0.00028 20.2 0.2 0.00053 19.4 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_50 PF18024.1 KFM77037.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KFM77037.1 - 0.0043 16.9 0.1 0.0084 15.9 0.1 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 KFM77037.1 - 0.007 16.1 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77037.1 - 0.0072 16.1 0.2 0.02 14.7 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KFM77037.1 - 0.034 14.0 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 MarR family MarR PF01047.22 KFM77037.1 - 0.11 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 MarR family HTH_7 PF02796.15 KFM77037.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_6 PF01418.17 KFM77037.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_11 PF08279.12 KFM77037.1 - 0.17 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 HTH domain Actin PF00022.19 KFM77038.1 - 4.9e-149 496.4 0.0 1.6e-148 494.7 0.0 1.7 1 1 0 1 1 1 1 Actin Aa_trans PF01490.18 KFM77039.1 - 3.4e-34 118.3 30.4 1.5e-18 66.7 16.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF4267 PF14087.6 KFM77039.1 - 0.054 13.6 0.1 0.49 10.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) DUF829 PF05705.14 KFM77040.1 - 1.8e-34 119.7 0.0 2.1e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 KFM77040.1 - 0.00039 19.9 0.0 0.00056 19.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family TMEM169 PF15052.6 KFM77040.1 - 0.0051 16.9 0.1 0.0082 16.3 0.1 1.2 1 0 0 1 1 1 1 TMEM169 protein family DLH PF01738.18 KFM77040.1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KFM77040.1 - 0.11 11.8 0.0 5.2 6.3 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 NfI_DNAbd_pre-N PF10524.9 KFM77042.1 - 3.5e-25 87.6 4.0 6.3e-25 86.8 4.0 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.16 KFM77042.1 - 7.8e-13 48.5 0.3 1.4e-12 47.7 0.3 1.5 1 0 0 1 1 1 1 MH1 domain CTF_NFI PF00859.18 KFM77042.1 - 2.6e-08 34.1 22.2 2.6e-08 34.1 22.2 2.6 1 1 1 2 2 2 1 CTF/NF-I family transcription modulation region Pkinase_Tyr PF07714.17 KFM77044.1 - 6.8e-36 123.9 0.3 7.9e-36 123.7 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM77044.1 - 4.3e-12 46.0 0.0 5.3e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM77045.1 - 4.7e-30 104.7 0.0 6.7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM77045.1 - 1.2e-17 64.1 0.0 2.1e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain tRNA-synt_1b PF00579.25 KFM77047.1 - 1.5e-12 47.4 0.0 1.6e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HTH_Tnp_Tc3_2 PF01498.18 KFM77048.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77048.1 - 6.3e-14 52.0 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77048.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77048.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM77048.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Ank_2 PF12796.7 KFM77049.1 - 1.9e-94 310.4 16.8 5.3e-20 71.8 0.7 7.3 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM77049.1 - 1.1e-79 261.9 5.0 1.7e-11 44.4 0.0 9.4 6 2 2 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM77049.1 - 1.1e-78 249.7 13.2 1.6e-06 28.0 0.0 14.3 14 0 0 14 14 14 13 Ankyrin repeat Ank PF00023.30 KFM77049.1 - 1.4e-75 246.7 21.2 1.5e-08 34.7 0.0 14.2 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.6 KFM77049.1 - 6.7e-60 198.4 18.8 4.7e-07 30.0 0.1 11.3 4 3 8 12 12 12 12 Ankyrin repeats (many copies) Amidinotransf PF02274.17 KFM77049.1 - 0.0025 17.0 4.1 1.8 7.6 0.3 3.6 3 1 0 3 3 3 2 Amidinotransferase Peptidase_M16 PF00675.20 KFM77049.1 - 0.0084 16.1 4.6 7.2 6.6 0.0 4.4 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) ScdA_N PF04405.14 KFM77049.1 - 3.7 7.3 6.5 24 4.7 0.1 5.1 6 0 0 6 6 6 0 Domain of Unknown function (DUF542) HLH PF00010.26 KFM77050.1 - 2.1e-14 53.2 0.4 3.9e-14 52.4 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM77051.1 - 0.00016 21.9 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 KFM77052.1 - 2.8e-19 69.1 3.6 6.6e-19 67.9 2.1 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77052.1 - 5.8e-16 58.6 0.0 2.8e-15 56.4 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM77052.1 - 2.8e-07 30.5 0.3 0.00018 21.5 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM77052.1 - 4.1e-07 30.5 2.0 4.1e-07 30.5 2.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM77052.1 - 1.4e-06 28.3 2.5 8.6e-05 22.6 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77052.1 - 2.1e-06 27.3 3.2 2.8e-05 23.8 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFM77052.1 - 3.4e-06 27.0 0.7 4.5e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KFM77052.1 - 0.00014 21.7 0.6 0.0018 18.1 0.0 2.5 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM77052.1 - 0.0013 18.6 0.3 0.018 15.0 0.0 2.3 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_22 PF13309.6 KFM77052.1 - 0.015 15.4 0.0 34 4.6 0.0 3.4 3 0 0 3 3 3 0 HTH domain GntR PF00392.21 KFM77052.1 - 0.024 14.3 0.1 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KFM77052.1 - 0.062 13.4 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KFM77052.1 - 0.11 12.7 0.1 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 KFM77052.1 - 0.32 10.8 3.6 1.6 8.6 0.0 3.0 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DTW PF03942.15 KFM77053.1 - 7.5e-40 136.8 0.0 9.1e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 DTW domain Pkinase PF00069.25 KFM77055.1 - 7.7e-08 32.0 0.0 7.8e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM77055.1 - 0.054 12.8 0.0 0.054 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KFM77056.1 - 9.7e-36 123.5 1.5 1.2e-35 123.2 1.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM77056.1 - 1.3e-22 80.4 1.0 1.5e-22 80.1 1.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM77056.1 - 0.012 15.0 0.4 0.11 11.8 0.5 2.0 1 1 1 2 2 2 0 Kinase-like DNA_pol_phi PF04931.13 KFM77056.1 - 0.019 13.1 0.2 0.025 12.7 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase_fungal PF17667.1 KFM77056.1 - 0.059 12.1 0.1 0.072 11.9 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase Tropomyosin_1 PF12718.7 KFM77057.1 - 0.0084 16.3 1.1 0.0084 16.3 1.1 2.3 1 1 1 2 2 2 1 Tropomyosin like Glyco_hydro_77 PF02446.17 KFM77057.1 - 0.012 14.5 0.1 0.02 13.8 0.1 1.3 1 1 0 1 1 1 0 4-alpha-glucanotransferase VGPC1_C PF16799.5 KFM77057.1 - 0.014 15.3 0.5 0.014 15.3 0.5 2.0 2 0 0 2 2 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 HAUS-augmin3 PF14932.6 KFM77057.1 - 0.024 14.2 4.9 0.031 13.8 4.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Lectin_N PF03954.14 KFM77057.1 - 0.024 14.4 1.6 0.024 14.4 1.6 2.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain BLOC1_2 PF10046.9 KFM77057.1 - 0.035 14.4 7.0 0.08 13.3 4.7 2.3 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.12 KFM77057.1 - 0.039 12.5 3.5 0.048 12.2 3.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 KFM77057.1 - 0.046 12.6 8.1 0.053 12.4 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IKBKB_SDD PF18397.1 KFM77057.1 - 0.14 11.5 5.6 0.18 11.1 5.6 1.1 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain DUF16 PF01519.16 KFM77057.1 - 0.3 11.6 8.0 1.7 9.2 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 ATG16 PF08614.11 KFM77057.1 - 0.35 11.1 17.7 0.12 12.6 1.5 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GP41 PF00517.17 KFM77057.1 - 0.4 10.5 3.7 1 9.2 0.3 2.1 1 1 1 2 2 2 0 Retroviral envelope protein Exonuc_VII_L PF02601.15 KFM77057.1 - 0.42 10.1 5.1 0.54 9.8 5.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 KFM77057.1 - 0.46 10.9 9.6 1.8 9.0 9.7 1.8 1 1 0 1 1 1 0 Fez1 STAT_alpha PF01017.20 KFM77057.1 - 0.53 10.2 7.8 1.3 8.8 6.0 2.2 1 1 1 2 2 2 0 STAT protein, all-alpha domain V_ATPase_I PF01496.19 KFM77057.1 - 0.58 8.0 4.2 0.7 7.7 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 KFM77057.1 - 1 9.7 3.9 2.8 8.3 0.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 KFM77057.1 - 1.2 9.2 6.9 2.8 7.9 6.7 1.8 1 1 0 1 1 1 0 Laminin Domain II DUF4988 PF16378.5 KFM77057.1 - 1.2 8.8 4.8 4.7 6.8 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function PspB PF06667.12 KFM77057.1 - 1.6 8.8 5.1 1.8 8.7 2.5 2.4 1 1 1 2 2 2 0 Phage shock protein B Fib_alpha PF08702.10 KFM77057.1 - 1.6 8.9 8.2 2.5 8.3 6.9 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 KFM77057.1 - 1.7 8.9 10.2 9 6.6 0.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 KFM77057.1 - 2 8.9 7.1 7.2 7.2 2.3 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 KFM77057.1 - 2.3 8.3 11.3 2.3 8.3 7.4 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KFM77057.1 - 2.6 8.1 6.1 10 6.2 6.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlgN PF05130.12 KFM77057.1 - 3.2 8.2 11.4 16 6.0 11.4 1.9 1 1 0 1 1 1 0 FlgN protein FAM76 PF16046.5 KFM77057.1 - 3.5 6.9 13.6 0.36 10.2 7.3 1.9 1 1 1 2 2 2 0 FAM76 protein DASH_Spc19 PF08287.11 KFM77057.1 - 3.5 7.5 14.1 2 8.3 4.0 2.3 1 1 1 2 2 2 0 Spc19 DUF2203 PF09969.9 KFM77057.1 - 4.5 8.0 6.5 3.1 8.5 3.8 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DivIC PF04977.15 KFM77057.1 - 7 6.5 6.8 3.1 7.6 0.7 2.7 1 1 1 2 2 2 0 Septum formation initiator SlyX PF04102.12 KFM77057.1 - 7.3 7.3 8.9 21 5.8 1.2 2.6 1 1 2 3 3 3 0 SlyX HTH_Tnp_Tc3_2 PF01498.18 KFM77058.1 - 5.2e-10 39.4 0.1 7.6e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77058.1 - 0.0095 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-LSD1 PF06943.12 KFM77059.1 - 0.098 12.5 3.0 5.4 6.9 0.8 2.2 2 0 0 2 2 2 0 LSD1 zinc finger Ank_4 PF13637.6 KFM77060.1 - 0.0041 17.7 0.1 0.0064 17.0 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM77061.1 - 5.3e-07 30.1 0.1 1.6e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM77061.1 - 7e-06 26.3 0.1 0.014 15.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFM77061.1 - 8.2e-05 23.1 0.2 0.00019 21.9 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM77061.1 - 0.00013 22.2 1.2 0.0014 18.9 0.1 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM77061.1 - 0.00046 20.4 0.1 1.1 10.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat TPT PF03151.16 KFM77062.1 - 7.8e-93 311.0 26.4 9.1e-93 310.8 26.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM77062.1 - 3.2e-17 63.0 34.3 3.4e-10 40.2 12.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFM77062.1 - 8.5e-05 21.9 25.2 0.00011 21.5 25.2 1.1 1 0 0 1 1 1 1 UAA transporter family Reeler PF02014.16 KFM77064.1 - 5.6e-11 43.3 0.0 6.4e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Reeler domain DDE_3 PF13358.6 KFM77065.1 - 1.6e-10 40.9 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SAB PF04382.13 KFM77065.1 - 0.045 13.8 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 SAB domain Clathrin_lg_ch PF01086.17 KFM77066.1 - 6.4e-52 176.9 23.3 1.6e-51 175.6 23.3 1.6 1 1 0 1 1 1 1 Clathrin light chain Lebercilin PF15619.6 KFM77068.1 - 0.0013 18.4 7.7 0.0015 18.2 7.7 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease CALCOCO1 PF07888.11 KFM77068.1 - 0.0041 16.0 5.4 0.0043 16.0 5.4 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like HAUS-augmin3 PF14932.6 KFM77068.1 - 0.0082 15.8 4.1 0.013 15.1 4.1 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 zf-C4H2 PF10146.9 KFM77068.1 - 0.018 15.4 7.0 0.023 15.0 7.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein CREPT PF16566.5 KFM77068.1 - 0.029 14.6 4.8 0.049 13.8 4.8 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fmp27_WPPW PF10359.9 KFM77068.1 - 0.048 12.5 5.5 0.059 12.2 5.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1664 PF07889.12 KFM77068.1 - 0.071 13.1 5.6 0.096 12.7 4.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KFM77068.1 - 0.1 10.5 2.1 0.11 10.4 2.1 1.1 1 0 0 1 1 1 0 Prominin DUF641 PF04859.12 KFM77068.1 - 0.14 12.5 5.0 0.29 11.5 5.0 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KFM77068.1 - 0.18 10.7 6.9 0.24 10.2 6.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 KFM77068.1 - 0.25 12.0 3.7 0.52 11.0 3.7 1.6 1 0 0 1 1 1 0 Initiation control protein YabA TMPIT PF07851.13 KFM77068.1 - 0.32 10.2 2.3 0.41 9.8 2.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF572 PF04502.13 KFM77068.1 - 0.33 10.5 6.6 0.41 10.2 6.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Uso1_p115_C PF04871.13 KFM77068.1 - 0.34 11.3 8.8 0.055 13.8 4.9 1.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fib_alpha PF08702.10 KFM77068.1 - 0.43 10.8 4.9 0.96 9.6 4.9 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMCO5 PF14992.6 KFM77068.1 - 0.58 9.7 6.8 0.79 9.2 6.8 1.2 1 0 0 1 1 1 0 TMCO5 family UPF0242 PF06785.11 KFM77068.1 - 0.88 9.6 10.2 1.3 9.1 10.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KFM77068.1 - 1 9.1 7.4 1.8 8.4 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 KFM77068.1 - 1.2 9.5 7.8 11 6.5 1.7 2.9 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KFM77068.1 - 9.4 6.4 14.5 0.76 10.0 6.6 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KFM77069.1 - 0.023 15.3 2.7 0.023 15.3 2.7 5.9 4 2 3 7 7 7 0 SlyX GPHR_N PF12537.8 KFM77069.1 - 2.8 8.1 3.9 5.9 7.1 0.4 3.1 2 1 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal HMMR_N PF15905.5 KFM77070.1 - 0.68 9.4 30.0 0.18 11.2 9.5 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal LPP PF04728.13 KFM77070.1 - 1.5 9.3 8.8 2.7 8.5 0.1 3.7 3 2 1 4 4 4 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 KFM77070.1 - 1.5 8.1 13.8 2.7 7.2 13.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KFM77070.1 - 1.9 8.8 19.9 1 9.7 1.7 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ACCA PF03255.14 KFM77070.1 - 1.9 8.3 13.9 3 7.7 5.6 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ADIP PF11559.8 KFM77070.1 - 2.9 7.9 28.4 0.75 9.9 16.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rx_N PF18052.1 KFM77070.1 - 3.5 8.0 12.0 10 6.5 4.0 2.8 1 1 0 2 2 2 0 Rx N-terminal domain CENP-Q PF13094.6 KFM77070.1 - 4.5 7.4 29.0 2.5 8.3 22.9 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1515 PF07439.11 KFM77070.1 - 5.4 7.1 7.6 2.1 8.4 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Fez1 PF06818.15 KFM77070.1 - 5.5 7.4 26.6 3.1e+02 1.7 26.6 2.1 1 1 0 1 1 1 0 Fez1 FAM76 PF16046.5 KFM77070.1 - 5.5 6.3 20.1 6.8 5.9 20.1 1.1 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 KFM77070.1 - 5.5 7.5 34.0 6.3 7.3 9.5 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2400 PF09674.10 KFM77070.1 - 7.5 6.5 12.2 1.4 8.9 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Glyco_transf_22 PF03901.17 KFM77071.1 - 2.6e-25 89.5 1.2 3e-25 89.3 1.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Vps5 PF09325.10 KFM77072.1 - 2.3e-82 276.1 17.2 5.2e-82 274.9 17.2 1.6 1 1 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KFM77072.1 - 5.4e-28 97.2 0.1 2.5e-27 95.1 0.0 2.2 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 KFM77072.1 - 3.3e-06 26.7 6.4 0.00019 21.0 6.4 2.5 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein GrpE PF01025.19 KFM77072.1 - 0.00049 19.8 5.8 0.00049 19.8 5.8 2.6 2 0 0 2 2 2 1 GrpE Seryl_tRNA_N PF02403.22 KFM77072.1 - 0.29 11.4 9.5 2.7 8.3 0.4 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DHR10 PF18595.1 KFM77072.1 - 0.76 9.9 19.2 2.9 8.0 6.2 3.0 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain BLOC1_2 PF10046.9 KFM77072.1 - 3.8 7.9 11.3 10 6.5 0.4 3.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec1 PF00995.23 KFM77073.1 - 0.00067 19.0 0.1 0.00071 18.9 0.1 1.0 1 0 0 1 1 1 1 Sec1 family EF_assoc_2 PF08356.12 KFM77075.1 - 2e-36 123.8 0.0 5e-36 122.6 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KFM77075.1 - 2.6e-25 88.9 0.0 3.7e-20 72.2 0.0 2.8 2 1 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 KFM77075.1 - 2.8e-22 78.1 0.1 1.8e-21 75.5 0.0 2.2 2 0 0 2 2 2 1 EF hand associated Roc PF08477.13 KFM77075.1 - 6.4e-17 61.9 0.0 8.5e-11 42.1 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 KFM77075.1 - 2.3e-07 30.2 0.0 0.0027 17.5 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain SRPRB PF09439.10 KFM77075.1 - 4.5e-07 29.5 1.0 1.1e-05 24.9 0.0 2.9 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KFM77075.1 - 4.6e-07 29.5 0.0 0.00038 20.0 0.0 3.4 3 1 1 4 4 4 1 ADP-ribosylation factor family EF-hand_1 PF00036.32 KFM77075.1 - 1.9e-06 27.0 0.1 0.0024 17.3 0.0 2.6 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 KFM77075.1 - 2.3e-06 27.7 0.0 0.0028 17.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM77075.1 - 4.2e-06 26.8 3.5 0.6 10.0 0.0 4.5 4 1 0 5 5 4 2 RsgA GTPase EF-hand_7 PF13499.6 KFM77075.1 - 1.1e-05 25.8 0.2 0.22 12.0 0.0 2.8 3 0 0 3 3 2 2 EF-hand domain pair AAA_7 PF12775.7 KFM77075.1 - 2.2e-05 24.1 0.0 0.14 11.6 0.0 2.6 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_24 PF13479.6 KFM77075.1 - 2.5e-05 24.1 0.0 0.09 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM77075.1 - 3.6e-05 24.0 0.0 0.038 14.3 0.0 3.1 2 2 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KFM77075.1 - 8.2e-05 22.5 1.6 0.44 10.3 0.1 3.7 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFM77075.1 - 0.00012 22.5 0.0 0.018 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFM77075.1 - 0.00013 22.4 0.1 0.037 14.4 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KFM77075.1 - 0.00014 22.4 0.0 0.22 12.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Septin PF00735.18 KFM77075.1 - 0.00019 20.9 0.0 0.32 10.2 0.0 2.4 2 0 0 2 2 2 2 Septin PduV-EutP PF10662.9 KFM77075.1 - 0.00035 20.3 0.7 0.36 10.6 0.4 3.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KFM77075.1 - 0.00098 19.1 0.0 0.048 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KFM77075.1 - 0.001 19.0 0.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 KFM77075.1 - 0.0027 17.7 0.0 0.6 10.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SPARC_Ca_bdg PF10591.9 KFM77075.1 - 0.0034 17.7 0.1 0.62 10.4 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dynamin_N PF00350.23 KFM77075.1 - 0.0068 16.5 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin family RNA_helicase PF00910.22 KFM77075.1 - 0.0069 16.8 0.0 6.2 7.3 0.0 2.9 3 0 0 3 3 2 0 RNA helicase FeoB_N PF02421.18 KFM77075.1 - 0.0073 15.8 0.6 3 7.3 0.0 3.0 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_14 PF13173.6 KFM77075.1 - 0.012 15.7 0.0 1.4 9.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 KFM77075.1 - 0.013 15.0 0.1 11 5.4 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein MCM PF00493.23 KFM77075.1 - 0.018 14.1 0.0 0.088 11.9 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain RuvB_N PF05496.12 KFM77075.1 - 0.02 14.6 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KFM77075.1 - 0.022 14.6 0.0 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.6 KFM77075.1 - 0.022 14.6 1.3 0.67 9.9 0.2 2.5 2 0 0 2 2 2 0 EF hand Gtr1_RagA PF04670.12 KFM77075.1 - 0.023 14.0 0.0 0.29 10.4 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 KFM77075.1 - 0.033 14.7 0.0 1.4 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KFM77075.1 - 0.035 13.7 0.2 6.4 6.3 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KFM77075.1 - 0.038 13.7 0.2 8.7 6.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KFM77075.1 - 0.049 13.8 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFM77075.1 - 0.056 13.0 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KFM77075.1 - 0.11 12.0 0.1 6.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATPase_2 PF01637.18 KFM77075.1 - 0.12 12.3 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFM77075.1 - 0.15 12.4 0.1 6.1 7.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KFM77075.1 - 0.15 11.3 0.0 15 4.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family FAM70 PF14967.6 KFM77076.1 - 0.02 14.4 0.4 0.027 14.0 0.4 1.1 1 0 0 1 1 1 0 FAM70 protein GTP_EFTU PF00009.27 KFM77077.1 - 1.5e-22 80.1 0.0 2.3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFM77077.1 - 2.3e-08 34.3 0.5 9.5e-08 32.3 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM77077.1 - 0.0043 17.1 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KFM77077.1 - 0.019 14.7 0.1 18 5.1 0.0 3.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D3 PF03143.17 KFM77077.1 - 0.019 15.3 0.0 0.057 13.7 0.0 1.9 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain RINT1_TIP1 PF04437.13 KFM77078.1 - 2.9e-110 369.5 15.7 2.9e-110 369.5 15.7 2.2 2 1 0 2 2 2 1 RINT-1 / TIP-1 family MitMem_reg PF13012.6 KFM77078.1 - 0.0033 17.8 3.3 0.065 13.7 1.7 2.7 1 1 1 2 2 2 1 Maintenance of mitochondrial structure and function DUP PF00674.18 KFM77078.1 - 0.0057 16.8 0.0 0.024 14.8 0.0 2.1 1 0 0 1 1 1 1 DUP family Syntaxin_2 PF14523.6 KFM77078.1 - 0.045 14.1 5.1 1.8 9.0 2.3 2.7 2 0 0 2 2 2 0 Syntaxin-like protein TPR_MLP1_2 PF07926.12 KFM77078.1 - 0.048 13.7 4.4 0.11 12.6 4.4 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein LOH1CR12 PF10158.9 KFM77078.1 - 0.07 13.2 3.3 0.22 11.6 2.6 2.2 1 1 0 1 1 1 0 Tumour suppressor protein IL32 PF15225.6 KFM77078.1 - 0.1 13.0 6.4 0.45 10.9 0.1 4.0 3 1 1 4 4 4 0 Interleukin 32 AATF-Che1 PF13339.6 KFM77078.1 - 0.14 12.9 3.7 0.84 10.3 3.7 2.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor PolC_DP2 PF03833.13 KFM77078.1 - 0.16 9.8 1.3 0.34 8.7 1.3 1.6 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 GrpE PF01025.19 KFM77078.1 - 0.86 9.2 6.6 4.3 7.0 3.6 3.3 3 1 0 3 3 3 0 GrpE Phage_Mu_Gam PF07352.12 KFM77078.1 - 6 6.8 10.8 8.4 6.3 8.0 2.6 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Exo_endo_phos_2 PF14529.6 KFM77079.1 - 2.3e-15 56.5 0.6 1e-14 54.4 0.1 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM77079.1 - 3.6e-08 33.2 0.1 7.9e-08 32.1 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SOGA PF11365.8 KFM77081.1 - 0.17 13.0 2.9 3.1 9.0 0.0 3.1 2 0 0 2 2 2 0 Protein SOGA Thiolase_N PF00108.23 KFM77082.1 - 1.6e-75 253.8 0.1 2.3e-75 253.3 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFM77082.1 - 4.2e-46 155.6 0.0 4.2e-45 152.4 0.0 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFM77082.1 - 1.8e-08 34.3 2.3 6.8e-08 32.4 0.1 2.8 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFM77082.1 - 0.44 10.4 3.5 3.3 7.7 0.1 3.1 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MAD PF05557.13 KFM77083.1 - 5.3e-05 21.8 26.5 7e-05 21.4 26.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein CENP-F_leu_zip PF10473.9 KFM77083.1 - 0.003 17.6 32.2 0.0035 17.4 14.7 3.5 2 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 KFM77083.1 - 0.032 14.7 4.7 0.032 14.7 4.7 4.0 1 1 2 3 3 2 0 Cell division protein ZapB DUF812 PF05667.11 KFM77083.1 - 0.051 12.5 23.8 0.058 12.3 23.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Ribosomal_L50 PF10501.9 KFM77083.1 - 0.059 13.5 3.2 0.16 12.1 3.2 1.8 1 0 0 1 1 1 0 Ribosomal subunit 39S MscS_porin PF12795.7 KFM77083.1 - 0.11 12.0 18.9 7.9 6.0 19.0 2.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Spc7 PF08317.11 KFM77083.1 - 0.23 10.3 28.9 0.69 8.7 11.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFM77083.1 - 0.71 9.9 29.5 1.3 9.1 8.4 3.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Phage-A118_gp45 PF10653.9 KFM77083.1 - 1 9.4 4.1 5.5 7.1 0.3 3.0 2 1 1 3 3 3 0 Protein gp45 of Bacteriophage A118 DUF2730 PF10805.8 KFM77083.1 - 1.5 9.0 14.1 0.84 9.8 6.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) CENP-H PF05837.12 KFM77083.1 - 2 8.9 25.6 0.17 12.3 6.6 3.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.19 KFM77083.1 - 3.5 5.4 18.1 4.2 5.2 10.2 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 KFM77083.1 - 5.8 7.4 21.2 2.2 8.7 0.4 5.5 2 2 5 7 7 7 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KFM77083.1 - 7.4 6.4 17.8 1.8 8.4 1.5 3.9 2 1 2 4 4 4 0 Septum formation initiator TRAF_BIRC3_bd PF16673.5 KFM77083.1 - 7.6 6.4 14.5 0.8 9.5 0.5 3.7 2 1 2 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain MAD PF05557.13 KFM77084.1 - 4.3e-46 157.6 18.5 5.2e-46 157.3 18.5 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein APG6_N PF17675.1 KFM77084.1 - 0.0085 16.6 12.2 0.0085 16.6 12.2 3.0 1 1 1 2 2 2 1 Apg6 coiled-coil region BRE1 PF08647.11 KFM77084.1 - 0.017 15.2 10.0 0.017 15.2 10.0 3.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase SlyX PF04102.12 KFM77084.1 - 0.022 15.4 13.5 0.2 12.3 2.5 3.8 2 2 1 3 3 3 0 SlyX DUF4132 PF13569.6 KFM77084.1 - 0.033 14.0 4.1 1.5 8.6 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4132) Leu_zip PF15294.6 KFM77084.1 - 0.059 12.9 23.0 0.11 12.0 10.3 2.2 1 1 1 2 2 2 0 Leucine zipper TMF_DNA_bd PF12329.8 KFM77084.1 - 0.64 10.0 34.9 0.16 12.0 3.6 4.2 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding PSI_PsaF PF02507.15 KFM77084.1 - 0.97 9.3 3.9 4 7.3 0.2 2.5 2 1 1 3 3 3 0 Photosystem I reaction centre subunit III Z1 PF10593.9 KFM77084.1 - 1 8.8 6.1 0.28 10.7 0.3 2.2 2 0 0 2 2 2 0 Z1 domain DUF1664 PF07889.12 KFM77084.1 - 1.1 9.3 8.6 2.7 8.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 KFM77084.1 - 1.5 8.2 31.0 0.54 9.6 14.1 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DASH_Dad2 PF08654.10 KFM77084.1 - 3.1 8.3 11.2 2.2 8.8 0.9 2.7 2 1 0 2 2 2 0 DASH complex subunit Dad2 Cep57_CLD_2 PF14197.6 KFM77084.1 - 3.9 7.6 19.3 6.6 6.9 0.2 3.6 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 eIF2_C PF09173.11 KFM77086.1 - 8.4e-37 125.3 0.4 2.1e-36 124.0 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KFM77086.1 - 1.2e-24 87.0 0.0 2.2e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFM77086.1 - 2.7e-10 40.5 0.2 7.7e-10 39.0 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KFM77086.1 - 0.00011 22.2 0.1 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFM77086.1 - 0.0025 17.9 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KFM77086.1 - 0.074 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 KFM77086.1 - 0.17 11.0 0.4 1.2 8.2 0.1 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Sema PF01403.19 KFM77087.1 - 4.1e-56 190.6 0.1 4.7e-56 190.4 0.1 1.0 1 0 0 1 1 1 1 Sema domain HTH_38 PF13936.6 KFM77088.1 - 2.6e-07 30.3 0.1 3e-07 30.1 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KFM77088.1 - 0.016 15.1 0.1 0.019 14.8 0.1 1.1 1 0 0 1 1 1 0 Tc3 transposase rve PF00665.26 KFM77090.1 - 1.2e-18 67.5 0.0 2.4e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KFM77090.1 - 1e-06 28.5 0.0 2.7e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 KFM77090.1 - 0.058 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain XhlA PF10779.9 KFM77090.1 - 0.25 11.5 1.7 3.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Ldl_recept_a PF00057.18 KFM77091.1 - 1.4e-16 60.4 22.7 1.7e-09 37.8 5.9 3.1 3 1 1 4 4 4 2 Low-density lipoprotein receptor domain class A EGF PF00008.27 KFM77091.1 - 6.1e-05 23.2 3.8 6.1e-05 23.2 3.8 4.0 2 2 2 4 4 4 1 EGF-like domain PRKCSH-like PF12999.7 KFM77091.1 - 0.0012 18.7 20.7 0.0012 18.7 20.7 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like hEGF PF12661.7 KFM77091.1 - 0.0058 17.2 1.0 0.0058 17.2 1.0 5.0 5 1 0 5 5 5 1 Human growth factor-like EGF cEGF PF12662.7 KFM77091.1 - 0.14 12.1 15.7 0.17 11.8 1.4 3.4 3 0 0 3 3 3 0 Complement Clr-like EGF-like zf-H2C2_2 PF13465.6 KFM77092.1 - 3.7e-38 128.3 55.5 4.3e-08 33.2 0.4 8.4 9 0 0 9 9 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM77092.1 - 2.6e-23 81.1 64.5 1.4e-05 25.3 1.7 7.7 8 0 0 8 8 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM77092.1 - 2.4e-21 74.6 56.8 0.0014 19.2 1.1 7.7 8 0 0 8 8 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM77092.1 - 2.9e-11 43.3 49.1 0.016 15.5 0.2 7.8 8 0 0 8 8 7 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM77092.1 - 3.8e-08 33.5 52.0 0.0035 17.7 2.2 8.3 8 0 0 8 8 7 5 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM77092.1 - 1.4e-06 28.5 39.0 0.0046 17.2 4.9 4.9 2 2 4 6 6 6 6 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFM77092.1 - 1.9e-05 24.2 38.7 0.094 12.3 0.1 8.0 8 0 0 8 8 8 3 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KFM77092.1 - 0.00015 21.6 43.9 0.33 11.0 0.3 8.0 7 1 0 7 7 7 4 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KFM77092.1 - 0.0034 17.6 10.5 7.5 6.9 0.2 5.8 6 0 0 6 6 6 1 zinc-ribbon zf-MYST PF17772.1 KFM77092.1 - 0.0043 16.6 33.9 0.41 10.3 0.7 6.6 4 2 3 7 7 7 3 MYST family zinc finger domain zf-CCHC_2 PF13696.6 KFM77092.1 - 0.0046 16.8 27.9 1.2 9.1 0.7 6.1 6 0 0 6 6 5 4 Zinc knuckle Zn-ribbon_8 PF09723.10 KFM77092.1 - 0.0072 16.4 32.4 0.075 13.2 1.2 6.2 4 2 2 6 6 6 2 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFM77092.1 - 0.014 15.2 3.2 0.18 11.7 0.3 7.7 8 1 0 8 8 8 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM77092.1 - 0.075 13.8 35.4 2.2 9.1 1.2 4.7 1 1 3 4 4 4 0 zinc-ribbon family ADK_lid PF05191.14 KFM77092.1 - 0.1 12.6 0.7 0.1 12.6 0.7 5.7 4 2 2 6 6 6 0 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KFM77092.1 - 0.2 11.4 43.3 0.41 10.5 0.7 7.2 7 0 0 7 7 7 0 C2H2-type zinc-finger domain TRAF6_Z2 PF18048.1 KFM77092.1 - 0.78 9.9 20.5 3.2 7.9 0.1 5.6 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 GAGA PF09237.11 KFM77092.1 - 0.81 9.5 0.0 0.81 9.5 0.0 5.2 2 2 4 6 6 6 0 GAGA factor zf-C2H2_11 PF16622.5 KFM77092.1 - 0.83 9.5 0.0 0.83 9.5 0.0 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type DUF2719 PF10891.8 KFM77092.1 - 2.1 8.3 10.6 0.068 13.1 2.8 2.4 1 1 3 4 4 4 0 Protein of unknown function (DUF2719) DUF3268 PF11672.8 KFM77092.1 - 2.4 8.5 21.4 1.7 9.0 0.6 4.0 1 1 4 5 5 5 0 zinc-finger-containing domain zf-C2H2_2 PF12756.7 KFM77092.1 - 3 8.3 48.0 3.5 8.0 2.3 6.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM77092.1 - 3.5 7.5 22.7 0.93 9.4 1.7 5.8 4 2 2 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 KFM77093.1 - 9.6e-43 142.8 28.9 1.2e-10 41.3 0.3 6.0 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM77093.1 - 3e-29 99.8 33.8 3.4e-06 27.2 0.6 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM77093.1 - 1e-22 78.8 31.2 0.00012 22.7 0.2 5.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM77093.1 - 8.4e-14 51.2 18.5 0.0019 18.1 0.0 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM77093.1 - 1.8e-12 47.2 17.4 0.025 14.9 0.5 5.3 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM77093.1 - 3.4e-12 46.3 26.5 0.0048 17.3 0.2 5.3 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM77093.1 - 1.5e-11 43.8 31.4 0.026 14.3 1.1 6.5 6 1 0 6 6 6 5 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFM77093.1 - 6.7e-07 29.6 21.9 0.51 10.7 0.8 5.0 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM77093.1 - 3.1e-06 26.9 15.1 0.62 10.0 1.5 5.5 5 1 0 5 5 5 2 zinc-finger of a C2HC-type BolA PF01722.18 KFM77093.1 - 5.6e-06 26.5 2.0 0.088 13.1 0.9 3.5 1 1 1 2 2 2 2 BolA-like protein GAGA PF09237.11 KFM77093.1 - 6.4e-05 22.7 10.7 0.83 9.5 0.2 4.5 1 1 4 5 5 5 2 GAGA factor zf-C2H2_3rep PF18868.1 KFM77093.1 - 0.00031 21.4 10.3 1.4 9.6 0.7 3.9 2 2 1 3 3 3 3 Zinc finger C2H2-type, 3 repeats C1_1 PF00130.22 KFM77093.1 - 0.0016 18.3 17.8 1.3 8.9 0.3 4.9 1 1 4 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFM77093.1 - 0.0023 17.5 15.0 0.44 10.2 0.0 4.6 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFM77093.1 - 0.0027 17.4 0.4 0.0027 17.4 0.4 5.0 5 0 0 5 5 5 1 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM77093.1 - 0.0038 17.2 12.4 2.8 8.1 0.1 4.8 5 0 0 5 5 5 1 Sec23/Sec24 zinc finger FYVE PF01363.21 KFM77093.1 - 0.0058 16.8 20.1 1.1 9.5 4.4 3.9 1 1 1 2 2 2 1 FYVE zinc finger zf-CHCC PF10276.9 KFM77093.1 - 0.006 16.6 8.1 16 5.6 0.0 4.8 5 0 0 5 5 5 0 Zinc-finger domain Baculo_IE-1 PF05290.11 KFM77093.1 - 0.0062 16.5 9.7 2.4 8.1 3.2 4.2 1 1 3 4 4 4 1 Baculovirus immediate-early protein (IE-0) zf-C2H2_9 PF16293.5 KFM77093.1 - 0.0089 15.9 15.2 8.7 6.3 0.1 5.0 2 2 3 5 5 5 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 KFM77093.1 - 0.014 15.5 16.7 2.5 8.3 0.1 5.0 1 1 4 5 5 5 0 KIAA1045 RING finger DUF3268 PF11672.8 KFM77093.1 - 0.079 13.3 6.3 0.93 9.8 0.5 2.4 2 1 0 2 2 2 0 zinc-finger-containing domain zf-met2 PF12907.7 KFM77093.1 - 0.088 13.0 18.0 9.4 6.5 0.3 5.3 5 0 0 5 5 5 0 Zinc-binding FYDLN_acid PF09538.10 KFM77093.1 - 0.091 13.5 4.7 25 5.6 0.0 4.1 2 2 2 4 4 4 0 Protein of unknown function (FYDLN_acid) zf-Paramyx-P PF13008.7 KFM77093.1 - 0.13 11.7 8.0 70 3.0 0.1 4.9 5 0 0 5 5 5 0 Zinc-binding domain of Paramyxoviridae V protein zf-trcl PF13451.6 KFM77093.1 - 0.21 11.5 10.2 2.5 8.1 0.6 4.1 4 1 0 4 4 4 0 Probable zinc-ribbon domain zf-BED PF02892.15 KFM77093.1 - 0.3 11.2 26.8 0.5 10.4 4.1 4.9 1 1 4 5 5 5 0 BED zinc finger C5HCH PF17982.1 KFM77093.1 - 0.36 11.0 13.5 12 6.2 0.2 5.0 4 1 0 5 5 5 0 NSD Cys-His rich domain zinc_ribbon_15 PF17032.5 KFM77093.1 - 0.39 11.5 12.2 3.5 8.5 0.5 3.0 1 1 2 3 3 3 0 zinc-ribbon family zf-C2HE PF16278.5 KFM77093.1 - 1.4 9.4 23.7 0.57 10.7 1.5 4.9 2 2 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-MYST PF17772.1 KFM77093.1 - 2.9 7.6 15.1 5.9 6.6 0.5 4.8 3 2 2 5 5 5 0 MYST family zinc finger domain zf-piccolo PF05715.13 KFM77093.1 - 4.9 7.4 9.1 15 5.8 0.2 3.2 2 1 1 3 3 3 0 Piccolo Zn-finger UBZ_FAAP20 PF15750.5 KFM77093.1 - 9.2 6.3 9.8 68 3.5 0.0 4.6 5 0 0 5 5 5 0 Ubiquitin-binding zinc-finger Cnd3 PF12719.7 KFM77095.1 - 2.4e-17 63.1 0.4 2.6e-17 62.9 0.4 1.0 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain TFIIIC_sub6 PF10419.9 KFM77097.1 - 1.4e-15 56.9 0.1 8.2e-15 54.5 0.1 2.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain COMM_domain PF07258.14 KFM77098.1 - 2e-14 53.5 0.1 4.1e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 COMM domain Glyco_tran_WecB PF03808.13 KFM77098.1 - 0.045 13.7 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family 7tm_1 PF00001.21 KFM77099.1 - 4.3e-14 52.5 2.5 4.9e-14 52.3 2.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SPC25 PF06703.11 KFM77099.1 - 0.039 13.8 2.2 0.044 13.6 1.6 1.3 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SecY PF00344.20 KFM77099.1 - 0.32 10.2 1.7 0.71 9.1 0.3 1.9 1 1 1 2 2 2 0 SecY translocase 7tm_1 PF00001.21 KFM77100.1 - 3.7e-30 105.1 8.3 4.4e-30 104.9 8.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM77100.1 - 5.6e-08 32.7 11.1 5.7e-08 32.7 10.5 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFM77100.1 - 1e-06 28.3 4.2 1.3e-06 28.0 4.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFM77100.1 - 0.00039 20.2 3.2 0.00065 19.5 3.2 1.3 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 KFM77100.1 - 0.0057 16.0 11.6 0.0069 15.7 11.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srt PF10321.9 KFM77100.1 - 0.021 13.8 11.4 0.029 13.4 11.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt HTH_Tnp_Tc3_2 PF01498.18 KFM77101.1 - 5.3e-16 58.6 3.5 5.9e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77101.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77101.1 - 2.2e-07 30.5 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77101.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM77101.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain 7tm_1 PF00001.21 KFM77102.1 - 6.1e-50 170.0 13.4 7.2e-50 169.7 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM77102.1 - 3.5e-08 33.2 7.5 5.3e-08 32.6 7.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM77102.1 - 3.7e-08 33.3 12.3 5.1e-08 32.9 12.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFM77102.1 - 0.00068 19.5 6.9 0.00094 19.0 3.0 2.1 1 1 1 2 2 2 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 KFM77102.1 - 0.0051 16.1 12.8 0.0099 15.2 12.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw SPC25 PF06703.11 KFM77102.1 - 3 7.6 5.2 0.47 10.2 0.7 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) TSP_1 PF00090.19 KFM77103.1 - 3.1e-08 33.7 8.6 3.1e-08 33.7 8.6 2.1 2 1 0 2 2 2 1 Thrombospondin type 1 domain DUF5548 PF17702.1 KFM77103.1 - 4.5 7.0 6.6 1.7 8.3 1.8 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5548) WD40 PF00400.32 KFM77104.1 - 0.00033 21.4 0.1 0.84 10.6 0.0 3.8 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM77104.1 - 0.001 19.3 0.0 1.1 9.6 0.0 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_1N PF02870.15 KFM77104.1 - 0.012 16.5 0.0 0.5 11.2 0.0 3.1 4 0 0 4 4 4 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DDE_Tnp_IS1595 PF12762.7 KFM77105.1 - 0.0012 18.9 0.1 0.0014 18.6 0.1 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain TMEM164 PF14808.6 KFM77106.1 - 6.7e-107 356.6 6.0 8e-107 356.3 6.0 1.0 1 0 0 1 1 1 1 TMEM164 family UQ_con PF00179.26 KFM77107.1 - 1.8e-44 150.8 0.1 2e-44 150.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM77107.1 - 0.0098 16.2 0.1 0.019 15.2 0.1 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFM77107.1 - 0.015 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KFM77107.1 - 0.049 13.5 0.1 0.076 12.9 0.1 1.4 1 1 0 1 1 1 0 UEV domain Reprolysin_2 PF13574.6 KFM77108.1 - 1.5e-30 106.5 0.2 3.5e-30 105.3 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM77108.1 - 1.6e-29 103.4 0.2 1.6e-29 103.4 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFM77108.1 - 1.3e-21 77.4 0.1 1.3e-21 77.4 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KFM77108.1 - 6.7e-14 52.5 24.9 6.7e-14 52.5 24.9 3.0 2 0 0 2 2 2 1 Disintegrin Reprolysin_4 PF13583.6 KFM77108.1 - 1.4e-10 41.2 0.8 4.9e-10 39.4 0.8 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KFM77108.1 - 1.2e-07 31.8 0.0 7.6e-06 26.0 0.0 2.7 1 1 1 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease UPF0370 PF13980.6 KFM77109.1 - 6.2 6.9 6.2 4.7 7.3 1.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) WD40 PF00400.32 KFM77111.1 - 8.5e-38 127.7 8.0 2.2e-06 28.3 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM77111.1 - 9.3e-18 64.3 0.1 6.4e-06 26.4 0.0 4.9 1 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 KFM77111.1 - 8.4e-14 50.9 0.6 1.6e-13 50.0 0.6 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 KFM77111.1 - 4e-12 45.7 0.9 0.0028 16.7 0.0 3.6 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFM77111.1 - 1e-08 34.3 0.1 0.016 13.9 0.0 3.7 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFM77111.1 - 0.001 17.9 0.5 1.7 7.3 0.0 4.0 2 2 1 4 4 4 1 Nup133 N terminal like Hira PF07569.11 KFM77111.1 - 0.0088 15.8 2.1 12 5.6 0.0 4.4 5 0 0 5 5 5 1 TUP1-like enhancer of split PD40 PF07676.12 KFM77111.1 - 0.078 12.9 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat FlaC_arch PF05377.11 KFM77111.1 - 1.6 9.2 3.6 26 5.3 3.6 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2054 PF10218.9 KFM77112.1 - 5.6e-47 159.2 21.4 6.8e-47 158.9 21.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) Adeno_E4_34 PF04528.13 KFM77112.1 - 0.11 12.3 1.2 0.14 12.0 1.2 1.2 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region RabGAP-TBC PF00566.18 KFM77113.1 - 0.012 15.2 1.0 0.013 15.2 1.0 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain FISNA PF14484.6 KFM77113.1 - 0.018 15.3 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 Fish-specific NACHT associated domain Fels1 PF05666.11 KFM77113.1 - 0.27 10.9 2.4 20 4.9 0.1 3.1 3 0 0 3 3 3 0 Fels-1 Prophage Protein-like Methyltransf_25 PF13649.6 KFM77116.1 - 2.8e-19 69.6 0.0 2.5e-10 40.9 0.0 3.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 KFM77116.1 - 1.4e-15 57.4 0.7 7.8e-10 38.7 0.1 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 KFM77116.1 - 8.5e-15 55.2 0.0 2.1e-10 41.1 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 KFM77116.1 - 2.2e-09 38.0 0.0 0.00043 21.0 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Spermine_synth PF01564.17 KFM77116.1 - 3.1e-09 36.5 2.6 9.1e-09 35.0 0.0 2.6 3 0 0 3 3 3 1 Spermine/spermidine synthase domain MTS PF05175.14 KFM77116.1 - 5.2e-09 35.9 0.0 0.00023 20.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_23 PF13489.6 KFM77116.1 - 5.4e-05 23.1 0.0 0.016 15.1 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFM77116.1 - 0.00016 21.7 0.0 0.19 11.7 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFM77116.1 - 0.00025 21.0 0.1 0.28 11.1 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain PCMT PF01135.19 KFM77116.1 - 0.0011 18.8 0.0 0.015 15.1 0.0 2.6 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_5 PF01795.19 KFM77116.1 - 0.0034 16.9 0.1 0.044 13.3 0.0 2.2 2 0 0 2 2 2 1 MraW methylase family Peptidase_A17 PF05380.13 KFM77116.1 - 0.0047 17.0 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase PrmA PF06325.13 KFM77116.1 - 0.0064 15.9 0.1 4.7 6.5 0.0 2.8 3 0 0 3 3 3 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KFM77116.1 - 0.026 13.8 0.1 0.29 10.4 0.0 2.3 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KFM77116.1 - 0.027 13.9 0.0 0.41 10.1 0.0 2.7 2 0 0 2 2 2 0 Putative methyltransferase MetW PF07021.12 KFM77116.1 - 0.12 12.0 0.1 6.2 6.4 0.0 2.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Syja_N PF02383.18 KFM77118.1 - 4.2e-81 272.7 0.7 4.7e-81 272.6 0.7 1.0 1 0 0 1 1 1 1 SacI homology domain HOOK PF05622.12 KFM77121.1 - 8.6e-31 106.8 62.6 8.6e-31 106.8 62.6 4.9 1 1 2 4 4 4 1 HOOK protein APG6_N PF17675.1 KFM77121.1 - 0.0006 20.4 21.7 0.0006 20.4 21.7 11.1 1 1 8 10 10 10 4 Apg6 coiled-coil region BRE1 PF08647.11 KFM77121.1 - 0.0023 18.0 9.5 0.0023 18.0 9.5 12.6 3 2 7 12 12 12 1 BRE1 E3 ubiquitin ligase GAS PF13851.6 KFM77121.1 - 0.0036 16.7 22.8 0.0036 16.7 22.8 11.1 4 3 6 11 11 11 7 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KFM77121.1 - 0.0051 16.9 13.5 0.0051 16.9 13.5 12.4 2 2 11 13 13 13 8 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 KFM77121.1 - 0.0083 16.4 27.7 0.011 16.0 14.7 13.3 4 4 8 13 13 13 5 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 KFM77121.1 - 0.013 15.9 3.4 0.013 15.9 3.4 16.4 5 3 8 15 15 15 0 Cell division protein ZapB Spc7 PF08317.11 KFM77121.1 - 0.032 13.1 174.3 0.053 12.4 17.5 8.1 2 2 4 7 7 7 0 Spc7 kinetochore protein CALCOCO1 PF07888.11 KFM77121.1 - 1.4 7.7 158.0 0.13 11.1 43.6 5.5 2 1 1 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1512 PF07431.12 KFM77121.1 - 2.9 6.8 7.8 0.59 9.1 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1512) PseudoU_synth_2 PF00849.22 KFM77122.1 - 8e-27 94.3 0.1 1.1e-26 93.9 0.1 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase DDE_1 PF03184.19 KFM77123.1 - 4.2e-17 62.3 0.1 7e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM77123.1 - 4.2e-12 45.9 0.4 9.5e-12 44.8 0.4 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFM77123.1 - 0.0026 17.5 0.0 0.0086 15.8 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3372 PF11852.8 KFM77123.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) LisH_2 PF16045.5 KFM77126.1 - 0.13 11.3 0.3 9 5.4 0.1 2.4 2 0 0 2 2 2 0 LisH DDE_3 PF13358.6 KFM77126.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM77127.1 - 2.3e-16 59.8 2.2 9.6e-16 57.8 1.5 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77127.1 - 7e-12 45.3 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM77127.1 - 0.073 13.7 8.7 0.12 13.0 0.9 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM77129.1 - 4.6e-16 58.8 3.5 5.5e-16 58.6 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77129.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77129.1 - 2e-07 30.7 1.2 6.9e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77129.1 - 0.0025 17.6 0.6 0.0074 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM77129.1 - 2.1 9.0 15.6 0.12 13.0 1.9 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM77130.1 - 2.2e-16 59.9 2.2 4.7e-16 58.8 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77130.1 - 1.1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease LSM PF01423.22 KFM77132.1 - 3.7e-23 81.0 0.1 4.6e-23 80.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFM77132.1 - 0.0003 20.9 0.0 0.00036 20.6 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain SF3b1 PF08920.10 KFM77133.1 - 3.3e-42 143.7 51.7 2e-41 141.2 17.2 5.5 1 1 3 4 4 4 3 Splicing factor 3B subunit 1 HEAT PF02985.22 KFM77133.1 - 9.8e-11 41.0 9.4 0.69 10.3 0.1 9.1 10 0 0 10 10 9 3 HEAT repeat HEAT_EZ PF13513.6 KFM77133.1 - 2.1e-10 40.9 3.9 0.53 10.8 0.0 7.2 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 KFM77133.1 - 6.9e-10 39.2 6.7 0.023 15.1 0.0 7.6 6 2 2 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KFM77133.1 - 1.6e-06 28.6 1.2 1.1 9.9 0.0 4.9 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFM77133.1 - 0.0018 18.3 12.9 1.8 8.6 0.0 6.2 5 2 2 8 8 8 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KFM77133.1 - 0.0018 17.9 1.8 4.8 6.7 0.1 4.0 3 1 1 4 4 4 1 CLASP N terminal NUC173 PF08161.12 KFM77133.1 - 0.0051 16.5 0.3 2.9 7.5 0.0 4.3 2 1 0 4 4 4 1 NUC173 domain TAF6_C PF07571.13 KFM77133.1 - 0.0076 16.5 0.0 0.94 9.9 0.0 3.2 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain DNA_pol_phi PF04931.13 KFM77133.1 - 0.011 13.9 0.0 0.99 7.4 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase phi UME PF08064.13 KFM77133.1 - 0.017 15.0 2.5 5.6 6.9 0.0 5.3 5 1 1 7 7 7 0 UME (NUC010) domain DRIM PF07539.12 KFM77133.1 - 0.049 11.9 0.1 14 3.8 0.0 3.1 2 1 0 3 3 3 0 Down-regulated in metastasis UNC45-central PF11701.8 KFM77133.1 - 0.085 12.8 0.1 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central MMS19_C PF12460.8 KFM77133.1 - 0.13 11.3 0.0 15 4.5 0.0 3.3 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF1428 PF07237.11 KFM77133.1 - 0.14 12.5 0.1 0.76 10.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1428) Arm PF00514.23 KFM77133.1 - 0.45 10.6 2.4 42 4.4 0.0 4.8 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat SF1-HH PF16275.5 KFM77134.1 - 6.6e-42 142.4 3.3 1.2e-41 141.5 1.9 2.3 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KFM77134.1 - 1.2e-08 34.6 1.6 2.9e-08 33.4 1.6 1.6 1 1 0 1 1 1 1 KH domain zf-CCHC PF00098.23 KFM77134.1 - 5.4e-07 29.4 7.7 1.2e-05 25.2 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KFM77134.1 - 0.011 15.6 6.3 0.96 9.5 0.4 2.5 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFM77134.1 - 0.025 14.3 5.8 0.44 10.3 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 KFM77134.1 - 0.041 13.7 6.6 2.4 8.1 0.9 3.3 2 0 0 2 2 2 0 Zinc knuckle PolC_DP2 PF03833.13 KFM77134.1 - 0.16 9.8 0.1 0.22 9.4 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_2 PF13240.6 KFM77134.1 - 0.56 10.0 5.6 4 7.3 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KFM77134.1 - 1.8 8.3 3.3 18 5.1 0.2 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.12 KFM77134.1 - 3.4 7.2 4.8 9 5.9 4.8 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding Rubredoxin_2 PF18073.1 KFM77134.1 - 5.6 6.8 9.6 0.62 9.8 2.8 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-CCHC_5 PF14787.6 KFM77134.1 - 6.3 6.6 11.4 7.6 6.3 0.6 3.4 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KFM77134.1 - 6.6 6.7 6.6 3.2 7.7 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle Prok-RING_1 PF14446.6 KFM77134.1 - 7 6.7 7.5 28 4.7 1.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Arf PF00025.21 KFM77135.1 - 4.8e-63 211.8 0.0 5.4e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFM77135.1 - 2.8e-10 39.9 0.5 2.4e-07 30.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFM77135.1 - 8.1e-09 35.7 0.0 1.9e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFM77135.1 - 4.8e-07 29.4 0.0 5.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFM77135.1 - 1.3e-06 28.4 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM77135.1 - 2e-06 27.4 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KFM77135.1 - 2.1e-06 27.5 0.0 2.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 KFM77135.1 - 0.0053 16.3 0.0 0.06 12.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KFM77135.1 - 0.046 13.3 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KFM77135.1 - 0.19 11.4 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.32 KFM77136.1 - 1.1 10.3 3.4 11 7.0 0.1 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Beach PF02138.18 KFM77137.1 - 4.8e-118 393.5 0.1 6.2e-118 393.2 0.1 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KFM77137.1 - 1.3e-09 38.0 0.0 4.1e-06 26.8 0.0 3.4 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH GRAM PF02893.20 KFM77137.1 - 2.6e-08 33.7 0.2 3.7e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 GRAM domain Vps36_ESCRT-II PF11605.8 KFM77137.1 - 0.014 15.5 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 WD40 PF00400.32 KFM77138.1 - 5.8e-21 74.4 11.2 0.0012 19.6 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM77138.1 - 2.1e-09 37.5 0.3 0.47 10.8 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KFM77138.1 - 0.00078 18.8 0.4 0.53 9.5 0.2 2.3 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.6 KFM77138.1 - 0.0072 16.8 1.1 3.2 8.4 0.0 3.9 3 2 0 3 3 3 1 PQQ-like domain WD40_like PF17005.5 KFM77138.1 - 0.0078 15.6 0.2 0.079 12.3 0.0 2.1 2 1 0 2 2 2 1 WD40-like domain PQQ PF01011.21 KFM77138.1 - 0.0092 15.9 1.9 1.3 9.0 0.1 4.1 4 0 0 4 4 4 1 PQQ enzyme repeat VID27 PF08553.10 KFM77138.1 - 0.082 11.9 0.0 4.4 6.2 0.0 2.2 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Vps16_N PF04841.13 KFM77138.1 - 0.14 10.9 0.1 0.18 10.5 0.1 1.4 1 1 0 1 1 1 0 Vps16, N-terminal region HTH_Tnp_Tc3_2 PF01498.18 KFM77139.1 - 4.5e-16 58.9 3.4 5.4e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77139.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77139.1 - 1.9e-07 30.7 1.2 6.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77139.1 - 0.0025 17.6 0.6 0.0073 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM77140.1 - 2e-16 60.0 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77140.1 - 7.6e-14 51.7 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM77141.1 - 2.1e-16 59.9 2.2 4.4e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77141.1 - 9.6e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MFS_1 PF07690.16 KFM77142.1 - 9.7e-41 139.9 30.3 1.2e-40 139.6 30.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM77142.1 - 1.5e-11 43.8 7.7 1.5e-11 43.8 7.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFM77142.1 - 7.5e-05 21.3 4.2 0.00011 20.8 4.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KFM77142.1 - 0.0029 16.5 18.7 0.044 12.6 18.7 2.5 1 1 0 1 1 1 1 MFS_1 like family zf-C2H2 PF00096.26 KFM77144.1 - 2e-16 59.4 18.9 1.8e-06 28.1 0.7 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM77144.1 - 2.8e-14 52.8 11.4 4.1e-07 30.1 0.3 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM77144.1 - 1e-11 44.6 16.6 0.00012 22.6 0.5 3.8 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM77144.1 - 1.2e-07 31.9 13.2 0.03 14.7 0.0 3.6 3 1 1 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM77144.1 - 2.7e-06 27.5 7.8 0.016 15.5 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFM77144.1 - 3.8e-05 23.2 1.5 0.16 11.6 0.0 3.3 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 KFM77144.1 - 5.2e-05 23.2 5.7 2 8.5 1.4 3.4 3 0 0 3 3 3 2 XPA protein N-terminal zf-C2H2_2 PF12756.7 KFM77144.1 - 0.00017 21.8 9.0 0.17 12.2 0.7 3.0 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM77144.1 - 0.00019 21.4 2.1 3.9 7.7 0.0 3.2 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2256) Sprouty PF05210.13 KFM77144.1 - 0.0008 19.8 1.5 0.0031 17.9 0.5 1.9 2 0 0 2 2 2 1 Sprouty protein (Spry) zf-C2H2_6 PF13912.6 KFM77144.1 - 0.0014 18.5 23.9 0.0093 15.9 2.6 4.3 4 1 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM77144.1 - 0.0018 18.0 10.4 0.56 10.0 0.3 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM77144.1 - 0.0049 16.7 9.6 0.29 11.1 0.3 3.3 3 0 0 3 3 3 1 zinc-finger of a C2HC-type Cript PF10235.9 KFM77144.1 - 0.014 16.0 4.5 5.7 7.6 2.3 3.0 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT HNH_5 PF14279.6 KFM77144.1 - 0.015 15.2 2.0 0.91 9.4 0.7 3.0 2 1 0 2 2 2 0 HNH endonuclease zf-BED PF02892.15 KFM77144.1 - 0.018 15.1 1.0 0.018 15.1 1.0 3.2 1 1 2 3 3 3 0 BED zinc finger zf-LYAR PF08790.11 KFM77144.1 - 0.025 14.5 4.0 7.2 6.6 0.1 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 KFM77144.1 - 0.029 14.5 5.6 0.33 11.1 0.3 2.6 2 1 1 3 3 3 0 Zinc ribbon domain LIM PF00412.22 KFM77144.1 - 0.03 14.6 9.2 0.14 12.4 5.4 2.6 2 1 1 3 3 3 0 LIM domain zf-Di19 PF05605.12 KFM77144.1 - 0.041 14.2 7.9 0.3 11.4 2.6 2.6 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.6 KFM77144.1 - 0.086 12.7 4.6 7.7 6.5 0.1 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain YhfH PF14149.6 KFM77144.1 - 0.088 12.8 3.0 10 6.2 0.0 2.9 3 0 0 3 3 3 0 YhfH-like protein zinc_ribbon_15 PF17032.5 KFM77144.1 - 0.1 13.4 0.9 0.1 13.4 0.9 1.9 1 1 0 2 2 2 0 zinc-ribbon family DNA_RNApol_7kD PF03604.13 KFM77144.1 - 0.16 11.7 6.7 1.3 8.8 0.3 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-AN1 PF01428.16 KFM77144.1 - 0.19 12.0 6.7 13 6.0 0.1 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger zf-HIT PF04438.16 KFM77144.1 - 0.22 11.4 8.9 2.9 7.9 0.2 3.0 3 0 0 3 3 3 0 HIT zinc finger zf-MYND PF01753.18 KFM77144.1 - 0.24 11.5 7.7 11 6.2 7.2 2.6 1 1 1 2 2 2 0 MYND finger zf-CRD PF17979.1 KFM77144.1 - 0.32 11.1 6.2 0.58 10.3 3.0 2.1 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions zinc_ribbon_4 PF13717.6 KFM77144.1 - 0.71 9.8 6.9 11 6.0 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-UBP PF02148.19 KFM77144.1 - 0.76 10.2 10.6 3.1 8.2 9.4 2.5 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zn_ribbon_recom PF13408.6 KFM77144.1 - 1.4 9.5 7.6 1.1e+02 3.4 7.6 2.4 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.7 KFM77144.1 - 1.4 8.9 11.3 1.5 8.9 2.8 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.12 KFM77144.1 - 1.9 8.8 8.3 0.35 11.1 2.1 2.2 1 1 0 2 2 2 0 TFIIH C1-like domain DZR PF12773.7 KFM77144.1 - 2.3 8.3 8.2 37 4.4 8.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C2HE PF16278.5 KFM77144.1 - 3.9 8.0 12.8 0.45 11.0 0.4 3.5 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger TFIIS_C PF01096.18 KFM77144.1 - 6.6 6.7 7.5 50 3.9 0.1 3.2 3 1 0 3 3 3 0 Transcription factor S-II (TFIIS) p450 PF00067.22 KFM77145.1 - 0.0025 16.7 0.1 0.0025 16.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0175 PF03683.13 KFM77145.1 - 0.028 14.1 0.1 0.035 13.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) p450 PF00067.22 KFM77146.1 - 1.2e-10 40.8 0.0 1.2e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.6 KFM77147.1 - 0.0035 17.1 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Neurochondrin PF05536.11 KFM77147.1 - 0.083 11.2 0.0 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin Astacin PF01400.24 KFM77149.1 - 1.6e-56 191.0 0.0 1.9e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM77149.1 - 0.047 13.5 0.0 0.99 9.2 0.0 2.6 3 0 0 3 3 3 0 Matrixin Astacin PF01400.24 KFM77150.1 - 3.6e-56 189.8 0.1 4.1e-56 189.6 0.1 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) HTH_Tnp_Tc3_2 PF01498.18 KFM77151.1 - 3.7e-14 52.7 1.0 6.8e-14 51.9 1.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77151.1 - 9.5e-14 51.4 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Astacin PF01400.24 KFM77152.1 - 4.3e-57 192.8 0.0 4.9e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) gag-asp_proteas PF13975.6 KFM77154.1 - 2.5e-13 50.4 0.5 2e-12 47.5 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFM77154.1 - 3.2e-12 46.9 0.1 1.8e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 KFM77154.1 - 4.2e-10 39.2 8.7 0.00011 22.1 0.8 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFM77154.1 - 1.4e-08 34.4 8.2 0.00066 19.5 2.0 2.6 2 0 0 2 2 2 2 Zinc knuckle Baculo_PEP_C PF04513.12 KFM77154.1 - 5e-08 33.1 9.7 9.5e-06 25.7 0.4 3.9 3 1 2 5 5 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 KFM77154.1 - 9.3e-06 25.8 41.4 0.00016 21.7 18.3 3.4 4 1 1 5 5 4 2 Protein of unknown function (DUF1640) Apolipoprotein PF01442.18 KFM77154.1 - 0.00023 21.1 35.2 0.00023 21.1 35.2 3.9 4 1 0 4 4 3 1 Apolipoprotein A1/A4/E domain HSBP1 PF06825.12 KFM77154.1 - 0.00024 20.9 12.7 1.3 8.9 0.0 5.8 5 1 0 5 5 5 2 Heat shock factor binding protein 1 zf-CCHC_4 PF14392.6 KFM77154.1 - 0.0038 16.9 4.5 0.091 12.5 0.6 2.6 2 0 0 2 2 2 1 Zinc knuckle Asp_protease PF09668.10 KFM77154.1 - 0.0041 16.9 0.0 0.0041 16.9 0.0 2.5 2 1 0 2 2 2 1 Aspartyl protease Prominin PF05478.11 KFM77154.1 - 0.0059 14.6 23.6 0.0057 14.7 21.3 1.8 2 0 0 2 2 2 1 Prominin DUF1664 PF07889.12 KFM77154.1 - 0.011 15.8 7.2 0.011 15.8 7.2 3.9 2 1 2 4 4 3 0 Protein of unknown function (DUF1664) HscB_4_cys PF18256.1 KFM77154.1 - 0.015 15.1 9.0 0.15 11.9 1.1 2.5 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif RVP PF00077.20 KFM77154.1 - 0.019 15.3 0.8 0.056 13.8 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease MLVIN_C PF18697.1 KFM77154.1 - 0.065 13.3 0.1 0.2 11.8 0.1 1.9 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain ApoLp-III PF07464.11 KFM77154.1 - 0.11 12.6 45.1 0.19 11.8 23.0 2.7 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Phasin PF05597.11 KFM77154.1 - 0.16 11.9 42.0 0.13 12.2 8.2 4.8 3 1 2 5 5 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Mu-like_Com PF10122.9 KFM77154.1 - 0.27 10.7 3.7 7.4 6.1 0.4 3.3 3 0 0 3 3 3 0 Mu-like prophage protein Com Peptidase_S64 PF08192.11 KFM77154.1 - 0.33 9.4 24.0 0.68 8.4 24.0 1.4 1 0 0 1 1 1 0 Peptidase family S64 DUF842 PF05811.13 KFM77154.1 - 0.34 10.6 25.9 0.013 15.2 14.3 2.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Spectrin PF00435.21 KFM77154.1 - 0.41 11.2 27.1 1.6 9.2 4.7 4.3 2 1 2 4 4 3 0 Spectrin repeat EzrA PF06160.12 KFM77154.1 - 0.47 8.6 32.7 1.8 6.7 32.7 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA zf-ribbon_3 PF13248.6 KFM77154.1 - 0.85 9.1 3.7 10 5.7 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain CdvA PF18822.1 KFM77154.1 - 1.2 9.0 38.5 3.4 7.5 3.9 5.3 1 1 3 5 5 5 0 CdvA-like coiled-coil domain ApoO PF09769.9 KFM77154.1 - 1.8 8.5 18.6 0.43 10.6 2.1 4.0 2 1 1 3 3 2 0 Apolipoprotein O GAS PF13851.6 KFM77154.1 - 2 7.7 41.6 0.11 11.8 34.4 2.7 4 0 0 4 4 3 0 Growth-arrest specific micro-tubule binding zf-FCS PF06467.14 KFM77154.1 - 2.5 8.1 4.4 24 5.0 0.2 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif AIP3 PF03915.13 KFM77154.1 - 2.7 7.0 39.7 82 2.1 36.7 3.2 1 1 2 3 3 3 0 Actin interacting protein 3 Zn_Tnp_IS1595 PF12760.7 KFM77154.1 - 4.1 7.5 5.9 0.44 10.6 0.6 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain SF-assemblin PF06705.11 KFM77154.1 - 5.9 6.2 39.1 36 3.6 39.1 2.2 1 1 0 1 1 1 0 SF-assemblin/beta giardin Spore_III_AB PF09548.10 KFM77154.1 - 6.1 6.9 20.8 12 6.0 17.6 2.8 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Mitofilin PF09731.9 KFM77154.1 - 9.1 5.0 42.2 2.7e+02 0.1 42.2 2.2 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Fzo_mitofusin PF04799.13 KFM77154.1 - 9.2 5.8 29.7 1.5 8.3 3.4 3.8 1 1 3 4 4 4 0 fzo-like conserved region DUF4713 PF15831.5 KFM77155.1 - 5.7 7.5 5.5 20 5.7 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4713) Astacin PF01400.24 KFM77156.1 - 4.4e-58 196.0 0.1 5.2e-58 195.8 0.1 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM77156.1 - 0.0045 16.8 7.6 0.69 9.8 0.1 3.1 2 1 1 3 3 3 2 Matrixin Reprolysin_3 PF13582.6 KFM77156.1 - 0.32 11.5 1.1 1.4 9.5 1.1 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ost4 PF10215.9 KFM77157.1 - 3.6e-15 55.5 1.0 4e-15 55.4 1.0 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase DDE_Tnp_1_7 PF13843.6 KFM77158.1 - 2.7e-06 26.9 0.0 2.7e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF573 PF04504.14 KFM77159.1 - 0.069 13.8 1.6 0.092 13.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF573 HSP90 PF00183.18 KFM77160.1 - 0.016 14.2 0.3 0.016 14.2 0.3 1.0 1 0 0 1 1 1 0 Hsp90 protein ESP PF16590.5 KFM77160.1 - 0.017 15.4 1.0 0.019 15.2 1.0 1.1 1 0 0 1 1 1 0 Exocrine gland-secreting peptide DUF19 PF01579.18 KFM77160.1 - 0.017 14.9 4.6 0.021 14.7 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF19) Q_salvage PF10343.9 KFM77160.1 - 0.085 12.4 0.1 0.088 12.4 0.1 1.0 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family 7tm_1 PF00001.21 KFM77161.1 - 8.3e-20 71.2 7.3 1.2e-19 70.7 7.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1700 PF08006.11 KFM77161.1 - 0.31 10.5 3.8 0.51 9.9 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Ycf4 PF02392.16 KFM77161.1 - 0.42 10.2 2.8 0.48 10.0 2.2 1.3 1 1 0 1 1 1 0 Ycf4 TMEM40 PF15817.5 KFM77161.1 - 1.7 8.4 4.7 1.1 9.1 2.1 1.9 1 1 1 2 2 2 0 Transmembrane protein 40 family KASH_CCD PF14662.6 KFM77162.1 - 0.0022 17.9 4.5 0.0049 16.7 4.5 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH XLF PF09302.11 KFM77162.1 - 0.0028 17.9 2.4 0.0089 16.2 2.1 1.9 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Sec2p PF06428.11 KFM77162.1 - 0.15 12.1 2.7 0.31 11.0 1.6 2.1 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p UPF0242 PF06785.11 KFM77162.1 - 0.57 10.2 6.1 1.2 9.2 6.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DDE_Tnp_1_7 PF13843.6 KFM77163.1 - 1.8e-06 27.5 0.0 1.8e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF2840 PF11000.8 KFM77163.1 - 0.13 12.0 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) HTH_Tnp_Tc3_2 PF01498.18 KFM77164.1 - 4.5e-16 58.9 2.2 4.5e-16 58.9 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77164.1 - 9.1e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM77165.1 - 2.1e-15 56.7 0.6 2.3e-15 56.6 0.6 1.0 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM77165.1 - 0.0035 17.9 1.0 0.0071 16.9 0.3 1.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_21 PF13276.6 KFM77165.1 - 0.023 14.8 0.2 0.031 14.4 0.2 1.3 1 0 0 1 1 1 0 HTH-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM77168.1 - 4.8e-16 58.8 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77168.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77168.1 - 2.1e-07 30.6 1.2 7.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77168.1 - 0.0028 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM77168.1 - 2.5 8.8 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Oxidored-like PF09791.9 KFM77169.1 - 0.54 10.0 5.0 0.45 10.2 4.0 1.4 1 1 0 1 1 1 0 Oxidoreductase-like protein, N-terminal LAMTOR5 PF16672.5 KFM77170.1 - 4.8e-24 84.1 0.2 5.4e-24 83.9 0.2 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 KFM77170.1 - 0.006 16.3 0.1 0.02 14.7 0.1 1.8 1 1 0 1 1 1 1 Roadblock/LC7 domain Ras PF00071.22 KFM77171.1 - 7.2e-53 178.5 0.0 8.6e-53 178.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM77171.1 - 5e-33 113.9 0.0 6.7e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM77171.1 - 2.3e-13 49.9 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM77171.1 - 3.3e-06 27.2 0.0 4.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFM77171.1 - 0.0047 16.5 0.0 0.0084 15.7 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFM77171.1 - 0.0085 15.5 0.0 0.0091 15.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFM77171.1 - 0.016 15.0 0.2 2.5 7.8 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KFM77171.1 - 0.017 14.8 0.1 0.067 12.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 KFM77171.1 - 0.023 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SRP54 PF00448.22 KFM77171.1 - 0.05 13.2 0.1 1.1 8.9 0.0 2.6 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KFM77171.1 - 0.093 12.6 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 KFM77171.1 - 0.12 12.6 0.3 0.84 9.9 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 KFM77171.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KFM77171.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain RLL PF10036.9 KFM77172.1 - 4.7e-79 265.9 0.0 5.2e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein ARL2_Bind_BART PF11527.8 KFM77172.1 - 0.0012 19.0 0.1 0.005 16.9 0.0 2.0 3 0 0 3 3 3 1 The ARF-like 2 binding protein BART MADF_DNA_bdg PF10545.9 KFM77173.1 - 8.6e-17 61.2 1.9 1.7e-16 60.3 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 KFM77173.1 - 0.0021 18.4 0.9 0.0048 17.2 0.9 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Transposase_mut PF00872.18 KFM77173.1 - 0.02 13.8 0.2 0.036 12.9 0.2 1.4 1 0 0 1 1 1 0 Transposase, Mutator family DUF3274 PF11678.8 KFM77173.1 - 0.14 11.4 1.2 7 5.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3274) MFS_1 PF07690.16 KFM77174.1 - 0.0067 15.4 0.1 0.0073 15.3 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily SMI1_KNR4 PF09346.10 KFM77174.1 - 0.12 12.8 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) 3Beta_HSD PF01073.19 KFM77175.1 - 7.9e-53 179.3 0.0 9.8e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFM77175.1 - 9.6e-21 74.3 0.0 1.2e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFM77175.1 - 1.6e-13 50.5 0.1 2.5e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFM77175.1 - 5.3e-10 38.9 0.0 5.8e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KFM77175.1 - 1.5e-08 34.5 0.0 2.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFM77175.1 - 1.7e-08 34.0 0.0 2.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFM77175.1 - 1.7e-08 34.6 0.0 2.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFM77175.1 - 0.00049 20.4 0.0 0.0015 18.8 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KFM77175.1 - 0.00096 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KFM77175.1 - 0.0013 19.1 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KFM77175.1 - 0.01 16.0 0.1 0.021 15.0 0.1 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TMEM144 PF07857.12 KFM77175.1 - 0.015 14.3 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters KR PF08659.10 KFM77175.1 - 0.062 13.2 0.0 0.36 10.7 0.0 1.9 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 KFM77175.1 - 0.064 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAGidase PF07555.13 KFM77175.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Pkinase_Tyr PF07714.17 KFM77176.1 - 4.6e-100 334.2 0.0 5.7e-100 333.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM77176.1 - 2.7e-51 174.4 0.0 4.1e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFM77176.1 - 6.3e-06 26.3 0.0 0.012 15.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM77176.1 - 0.0073 15.7 0.0 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFM77176.1 - 0.065 12.6 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM77176.1 - 0.08 12.5 0.2 0.25 10.9 0.2 1.9 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFM77176.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFM77176.1 - 0.11 11.5 0.1 0.2 10.6 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Ribosomal_S20p PF01649.18 KFM77176.1 - 0.48 11.1 1.5 0.61 10.8 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S20 Arf PF00025.21 KFM77177.1 - 5e-47 159.6 0.0 5.6e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFM77177.1 - 3.1e-07 29.9 0.0 4.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 KFM77177.1 - 0.00099 19.3 0.0 0.0013 19.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM77177.1 - 0.046 13.3 0.0 0.055 13.1 0.0 1.1 1 0 0 1 1 1 0 Ras family MMR_HSR1 PF01926.23 KFM77177.1 - 0.052 13.6 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM77177.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PCNA_N PF00705.18 KFM77179.1 - 4.4e-57 191.3 1.4 4.8e-57 191.1 1.4 1.0 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 KFM77179.1 - 0.0011 18.5 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Rad9 PCNA_C PF02747.15 KFM77180.1 - 1.1e-53 180.8 0.0 1.2e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 KFM77180.1 - 0.0038 16.3 0.0 0.0044 16.1 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 TBCA PF02970.16 KFM77181.1 - 0.0071 16.6 0.3 0.0076 16.6 0.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A YojJ PF10372.9 KFM77181.1 - 0.02 15.0 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus PAPA-1 PF04795.12 KFM77181.1 - 0.024 15.4 1.4 0.032 15.0 1.4 1.1 1 0 0 1 1 1 0 PAPA-1-like conserved region Nas2_N PF18265.1 KFM77181.1 - 0.11 12.5 0.8 0.13 12.2 0.8 1.2 1 0 0 1 1 1 0 Nas2 N_terminal domain Ras PF00071.22 KFM77183.1 - 2.6e-41 140.9 0.1 3.2e-41 140.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM77183.1 - 3.7e-28 98.2 0.1 4.6e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM77183.1 - 2e-14 53.5 0.0 2.3e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFM77183.1 - 7.5e-06 25.5 0.1 1e-05 25.0 0.1 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFM77183.1 - 0.00022 20.8 0.0 0.00057 19.5 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM77183.1 - 0.0003 20.9 0.0 0.00049 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM77183.1 - 0.0018 17.7 0.1 0.0022 17.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KFM77183.1 - 0.031 14.7 0.0 0.24 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFM77183.1 - 0.031 14.5 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KFM77183.1 - 0.053 12.9 0.0 1.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KFM77183.1 - 0.094 12.6 0.0 7.6 6.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 KFM77183.1 - 0.16 12.4 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 KFM77184.1 - 7.3e-45 152.5 0.0 8.8e-45 152.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM77184.1 - 9.4e-30 103.3 0.0 1.4e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM77184.1 - 1e-12 47.8 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM77184.1 - 7.4e-05 22.8 0.0 0.00019 21.5 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFM77184.1 - 0.00036 20.1 0.0 0.00067 19.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TBSV_P22 PF03558.13 KFM77184.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 TBSV core protein P21/P22 DDE_3 PF13358.6 KFM77185.1 - 1.8e-10 40.7 0.0 2.5e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ras PF00071.22 KFM77186.1 - 6.7e-18 64.8 0.0 8e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM77186.1 - 0.00021 21.5 0.2 0.00099 19.3 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase OKR_DC_1_N PF03709.15 KFM77186.1 - 0.018 15.3 0.2 1.7 8.9 0.2 2.1 1 1 1 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ras PF00071.22 KFM77187.1 - 3e-20 72.4 0.4 3.3e-20 72.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM77187.1 - 6.9e-16 58.5 0.2 7.7e-16 58.4 0.2 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM77187.1 - 6.6e-05 22.4 0.0 6.9e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM77187.1 - 0.0008 19.5 0.1 0.00091 19.3 0.1 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KFM77187.1 - 0.00098 18.5 0.2 0.0016 17.8 0.2 1.3 1 1 0 1 1 1 1 Septin AAA_24 PF13479.6 KFM77187.1 - 0.0062 16.3 0.0 0.0062 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM77187.1 - 0.0066 16.4 0.0 0.0072 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KFM77187.1 - 0.0073 16.2 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KFM77187.1 - 0.0083 16.4 0.0 0.009 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFM77187.1 - 0.0086 15.6 0.0 0.0086 15.6 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region Pox_A32 PF04665.12 KFM77187.1 - 0.011 15.2 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein Gtr1_RagA PF04670.12 KFM77187.1 - 0.017 14.5 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.26 KFM77187.1 - 0.019 14.6 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 KFM77187.1 - 0.041 14.3 0.0 0.041 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KFM77187.1 - 0.043 13.6 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KFM77187.1 - 0.063 12.8 0.1 0.066 12.7 0.1 1.0 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KFM77187.1 - 0.063 12.7 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 KFM77187.1 - 0.079 12.9 0.0 0.092 12.7 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KFM77187.1 - 0.092 12.9 0.0 0.092 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFM77187.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein AAA_25 PF13481.6 KFM77187.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM77187.1 - 0.15 12.6 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter SapB_1 PF05184.15 KFM77190.1 - 7.5e-22 77.0 25.5 8.8e-11 41.6 2.3 4.3 4 0 0 4 4 4 3 Saposin-like type B, region 1 SapB_2 PF03489.17 KFM77190.1 - 8.6e-21 73.7 20.8 1.5e-08 34.6 0.4 5.2 5 0 0 5 5 5 3 Saposin-like type B, region 2 SapA PF02199.15 KFM77190.1 - 4.6e-05 23.6 0.8 4.6e-05 23.6 0.8 3.4 3 0 0 3 3 3 1 Saposin A-type domain MgtE_N PF03448.17 KFM77190.1 - 0.012 16.2 0.4 0.16 12.6 0.7 2.6 3 1 0 3 3 3 0 MgtE intracellular N domain DUF2294 PF10057.9 KFM77190.1 - 0.02 15.0 0.4 10 6.3 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) RGS PF00615.19 KFM77190.1 - 0.036 14.3 0.4 3.3 8.0 0.0 3.0 3 0 0 3 3 3 0 Regulator of G protein signaling domain ATP-cone PF03477.16 KFM77190.1 - 0.069 13.7 1.5 0.36 11.4 0.3 2.7 2 2 2 4 4 4 0 ATP cone domain nsp8 PF08717.10 KFM77190.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 nsp8 replicase RPAP1_N PF08621.10 KFM77190.1 - 0.21 11.4 0.9 4.1 7.2 0.4 2.3 2 0 0 2 2 2 0 RPAP1-like, N-terminal DUF4599 PF15371.6 KFM77190.1 - 0.28 11.8 3.0 7.3 7.2 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4599) LRV_FeS PF05484.11 KFM77190.1 - 5.5 7.1 9.1 7.7 6.6 0.5 3.9 3 0 0 3 3 3 0 LRV protein FeS4 cluster HTH_Tnp_Tc3_2 PF01498.18 KFM77191.1 - 1.5e-17 63.6 1.6 2.1e-17 63.1 0.8 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77191.1 - 2e-14 53.6 0.0 3.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM77191.1 - 0.0005 20.6 5.7 0.0016 19.0 0.4 2.9 3 0 0 3 3 3 1 Homeodomain-like domain DDE_3 PF13358.6 KFM77192.1 - 7.1e-16 58.3 0.1 7e-15 55.1 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM77192.1 - 7.8e-16 58.1 6.5 1.6e-15 57.1 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM77192.1 - 0.00053 20.6 1.8 0.00053 20.6 1.8 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM77192.1 - 0.032 14.0 1.0 1 9.3 0.0 3.4 4 0 0 4 4 4 0 Homeodomain-like domain HTH_7 PF02796.15 KFM77192.1 - 0.078 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KFM77192.1 - 0.19 11.8 3.4 0.13 12.3 0.6 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Ig_3 PF13927.6 KFM77193.1 - 5.1e-30 103.9 0.1 3e-14 53.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM77193.1 - 4.4e-28 97.2 0.0 1.1e-12 47.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM77193.1 - 4.3e-19 68.5 0.0 5.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM77193.1 - 5.1e-18 65.2 0.0 1.3e-09 38.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM77193.1 - 3.3e-10 40.1 0.1 0.00045 20.4 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFM77193.1 - 4.8e-06 26.5 0.1 0.052 13.6 0.0 3.7 3 2 0 3 3 3 2 C17orf99 Ig domain C2-set_2 PF08205.12 KFM77193.1 - 5.3e-06 26.4 0.1 0.014 15.4 0.1 3.0 2 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain DDE_Tnp_1_7 PF13843.6 KFM77194.1 - 2.1e-69 234.5 0.0 2.5e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Kinesin PF00225.23 KFM77195.1 - 2e-63 214.4 0.8 2e-63 214.4 0.8 2.2 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 KFM77195.1 - 0.0019 18.4 7.9 0.0028 17.8 3.9 2.9 1 1 2 3 3 3 1 Kinesin-associated DUF745 PF05335.13 KFM77195.1 - 0.002 17.9 12.3 0.002 17.9 12.3 2.7 2 2 0 2 2 2 1 Protein of unknown function (DUF745) Fib_alpha PF08702.10 KFM77195.1 - 0.018 15.2 9.4 0.018 15.2 9.4 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 KFM77195.1 - 2.3 7.7 20.3 3.3 7.2 9.7 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit ST7 PF04184.12 KFM77195.1 - 3.3 6.1 6.4 5.4 5.4 6.4 1.2 1 0 0 1 1 1 0 ST7 protein Kinesin PF00225.23 KFM77196.1 - 1.7e-44 152.1 0.0 1.9e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM77196.1 - 3.8e-25 88.6 0.0 4.6e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KFM77196.1 - 0.01 16.2 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF2791 PF10923.8 KFM77196.1 - 0.014 14.3 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) PIF1 PF05970.14 KFM77196.1 - 0.022 13.9 0.2 0.037 13.2 0.2 1.4 1 1 0 1 1 1 0 PIF1-like helicase Bac_DnaA PF00308.18 KFM77196.1 - 0.026 14.4 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 KFM77196.1 - 0.054 13.4 0.1 0.071 13.0 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KFM77196.1 - 0.096 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFM77196.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFM77196.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFM77196.1 - 0.14 12.6 0.1 0.32 11.4 0.1 1.6 1 1 0 1 1 1 0 RNA helicase Pelovaterin PF17859.1 KFM77197.1 - 0.014 15.6 2.2 0.02 15.2 0.4 2.3 2 0 0 2 2 2 0 Pelovaterin DUF4371 PF14291.6 KFM77199.1 - 4e-10 39.8 0.0 7.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) PepX_C PF08530.10 KFM77199.1 - 0.24 11.3 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain HTH_Tnp_Tc3_2 PF01498.18 KFM77200.1 - 2.3e-16 59.8 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77200.1 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_S10 PF00450.22 KFM77202.1 - 1.4e-138 462.8 0.3 1.6e-138 462.7 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 KFM77202.1 - 0.086 12.3 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Dishevelled PF02377.15 KFM77203.1 - 4.3e-51 173.6 30.7 4.3e-51 173.6 30.7 2.0 2 1 0 2 2 2 1 Dishevelled specific domain DIX PF00778.17 KFM77203.1 - 4.1e-32 109.8 0.1 7.4e-32 109.0 0.1 1.4 1 0 0 1 1 1 1 DIX domain PDZ PF00595.24 KFM77203.1 - 7.4e-19 67.9 1.1 1.3e-18 67.1 1.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM77203.1 - 3.6e-06 26.7 0.1 6.5e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM77203.1 - 0.0026 18.0 0.2 0.0066 16.8 0.2 1.7 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.12 KFM77203.1 - 0.1 12.0 0.2 0.2 11.1 0.1 1.5 2 0 0 2 2 2 0 Bacterial shufflon protein, N-terminal constant region NAD_Gly3P_dh_N PF01210.23 KFM77204.1 - 6.2e-48 162.7 0.1 8.4e-48 162.3 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KFM77204.1 - 4.4e-35 121.1 2.4 3e-34 118.4 0.4 2.6 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Astacin PF01400.24 KFM77205.1 - 1.1e-53 181.7 0.0 1.2e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFM77205.1 - 0.088 11.7 0.4 0.083 11.8 0.4 1.1 1 0 0 1 1 1 0 Peptidase M66 DUF3267 PF11667.8 KFM77205.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative zincin peptidase RT_RNaseH PF17917.1 KFM77208.1 - 3.3e-27 94.8 0.0 5.4e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KFM77208.1 - 1.1e-25 89.6 0.3 1.7e-25 89.0 0.3 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LRR_5 PF13306.6 KFM77208.1 - 0.13 12.3 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) zf-H2C2_2 PF13465.6 KFM77209.1 - 3.8e-59 194.6 116.8 1.7e-08 34.5 1.1 15.2 14 2 0 14 14 14 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM77209.1 - 2.3e-45 150.6 122.6 6.5e-05 23.2 2.4 14.6 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM77209.1 - 3e-41 136.5 115.8 0.0025 18.5 0.1 14.4 14 0 0 14 14 14 14 C2H2-type zinc finger zf-met PF12874.7 KFM77209.1 - 9.7e-20 70.3 86.9 0.0003 21.1 0.5 13.0 13 0 0 13 13 13 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM77209.1 - 4.4e-15 55.5 82.0 0.046 14.0 0.2 14.0 14 0 0 14 14 14 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM77209.1 - 5.7e-12 45.3 110.9 0.092 12.8 0.1 14.8 15 0 0 15 15 15 11 C2H2-type zinc finger BolA PF01722.18 KFM77209.1 - 6.5e-08 32.7 22.8 0.75 10.1 1.3 9.3 3 3 7 11 11 11 2 BolA-like protein Zf_RING PF16744.5 KFM77209.1 - 1.3e-05 25.2 60.4 0.47 10.6 1.7 11.2 2 2 10 12 12 12 7 KIAA1045 RING finger zf-C2H2_11 PF16622.5 KFM77209.1 - 0.0074 16.0 91.2 0.089 12.6 1.8 13.2 14 0 0 14 14 14 6 zinc-finger C2H2-type zf_UBZ PF18439.1 KFM77209.1 - 0.36 10.5 70.1 5.1 6.8 0.1 13.6 14 0 0 14 14 14 0 Ubiquitin-Binding Zinc Finger Ank_2 PF12796.7 KFM77210.1 - 2.5e-31 108.1 1.1 9.6e-16 58.2 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM77210.1 - 3.6e-31 107.1 1.1 3.9e-14 52.8 0.2 5.6 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM77210.1 - 7.5e-29 99.4 5.2 3.1e-10 40.1 0.3 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFM77210.1 - 5e-24 83.6 7.5 5.5e-06 26.6 0.2 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFM77210.1 - 8.5e-22 74.9 4.5 0.00016 21.8 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat zf-RING_UBOX PF13445.6 KFM77211.1 - 0.015 15.3 2.3 0.2 11.7 0.4 2.4 2 0 0 2 2 2 0 RING-type zinc-finger Peptidase_M22 PF00814.25 KFM77212.1 - 3.9e-26 92.4 0.0 4.4e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family GTP_cyclohydro2 PF00925.20 KFM77212.1 - 0.077 12.6 0.1 0.08 12.5 0.1 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase II Carbam_trans_N PF02543.15 KFM77212.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Peptidase_M22 PF00814.25 KFM77213.1 - 7.9e-54 183.2 0.0 9e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DeoC PF01791.9 KFM77214.1 - 1.7e-22 80.2 0.1 2.2e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase HEM4 PF02602.15 KFM77215.1 - 9.9e-36 123.2 0.0 1.1e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD ACT_7 PF13840.6 KFM77215.1 - 0.042 13.6 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 ACT domain SeqA_N PF17206.3 KFM77215.1 - 0.083 12.2 0.0 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 SeqA protein N-terminal domain RE_MjaI PF09568.10 KFM77215.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 MjaI restriction endonuclease PA PF02225.22 KFM77216.1 - 8.3e-07 29.0 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 PA domain Tetraspanin PF00335.20 KFM77217.1 - 5.2e-54 183.4 13.3 6e-54 183.2 13.3 1.0 1 0 0 1 1 1 1 Tetraspanin family HTH_Tnp_Tc5 PF03221.16 KFM77218.1 - 0.0002 21.3 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CofC PF01983.16 KFM77218.1 - 0.049 12.8 0.1 0.064 12.4 0.1 1.1 1 0 0 1 1 1 0 Guanylyl transferase CofC like PLAT PF01477.23 KFM77219.1 - 3.7e-06 27.5 0.0 4.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 PLAT/LH2 domain HTH_Tnp_Tc3_2 PF01498.18 KFM77220.1 - 1.1e-16 60.8 1.9 4.2e-16 59.0 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77220.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PHD PF00628.29 KFM77222.1 - 0.26 11.2 21.1 0.063 13.2 17.2 2.1 2 0 0 2 2 2 0 PHD-finger zf-MYST PF17772.1 KFM77223.1 - 8.4e-21 73.3 0.7 9.7e-21 73.1 0.7 1.1 1 0 0 1 1 1 1 MYST family zinc finger domain UBZ_FAAP20 PF15750.5 KFM77223.1 - 0.012 15.6 0.4 0.022 14.7 0.4 1.5 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger zf-met PF12874.7 KFM77223.1 - 0.023 15.1 0.3 0.039 14.3 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type HTH_5 PF01022.20 KFM77223.1 - 0.028 14.3 0.1 0.04 13.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family zf-C2HE PF16278.5 KFM77223.1 - 0.029 14.8 0.1 0.03 14.8 0.1 1.2 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KFM77223.1 - 0.031 14.5 0.2 0.049 13.9 0.2 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFM77223.1 - 0.36 11.8 2.4 0.74 10.8 2.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger UCR_Fe-S_N PF10399.9 KFM77224.1 - 0.095 12.1 0.1 0.21 11.0 0.1 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF4817 PF16087.5 KFM77225.1 - 7.9e-08 32.0 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_30 PF13556.6 KFM77225.1 - 0.14 12.0 0.1 5.5 6.9 0.0 2.8 2 1 1 3 3 3 0 PucR C-terminal helix-turn-helix domain zf-H2C2_2 PF13465.6 KFM77226.1 - 4e-46 153.5 60.1 5.4e-07 29.8 0.1 10.3 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM77226.1 - 2e-40 135.0 72.5 4.3e-05 23.7 0.5 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM77226.1 - 1.9e-33 112.3 69.1 0.001 19.7 0.2 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM77226.1 - 7.3e-23 80.2 53.2 0.0017 18.7 0.3 10.2 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM77226.1 - 1.8e-21 75.9 40.3 0.00016 21.8 0.2 10.2 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM77226.1 - 1.7e-16 59.8 52.5 0.11 12.5 1.1 10.6 10 1 0 10 10 10 8 C2H2-type zinc finger DUF2256 PF10013.9 KFM77226.1 - 4.6e-05 23.4 33.5 0.42 10.8 0.1 9.5 10 0 0 10 10 10 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFM77226.1 - 5.9e-05 22.9 48.8 0.34 10.9 0.0 9.8 10 0 0 10 10 10 3 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KFM77226.1 - 5.9e-05 23.3 43.4 0.01 16.1 0.6 6.5 1 1 6 8 8 8 6 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KFM77226.1 - 6.6e-05 22.4 28.4 0.071 12.7 0.1 8.1 7 2 1 8 8 8 1 MYST family zinc finger domain Zn-C2H2_12 PF18112.1 KFM77226.1 - 0.00037 20.9 29.1 0.057 13.9 0.0 7.3 9 0 0 9 9 8 3 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 KFM77226.1 - 0.00053 19.8 15.8 2.6 8.0 2.1 6.7 4 3 4 8 8 8 1 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM77226.1 - 0.00074 19.6 43.3 0.074 13.2 0.7 6.4 1 1 5 6 6 6 2 FYVE zinc finger zf_UBZ PF18439.1 KFM77226.1 - 0.0016 18.0 39.0 0.62 9.7 0.1 9.4 10 0 0 10 10 10 2 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KFM77226.1 - 0.0018 19.0 28.9 2.1 9.1 3.1 5.4 1 1 5 6 6 6 2 zinc-ribbon family zf-H2C2_5 PF13909.6 KFM77226.1 - 0.0027 17.4 28.2 0.057 13.2 0.0 7.3 7 0 0 7 7 7 2 C2H2-type zinc-finger domain Acyltransf_C PF16076.5 KFM77226.1 - 0.032 14.3 3.7 2.3 8.4 0.1 3.0 2 1 0 3 3 2 0 Acyltransferase C-terminus Prok-RING_1 PF14446.6 KFM77226.1 - 0.078 12.9 32.4 2.1 8.3 0.0 8.9 9 1 0 9 9 9 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 KFM77226.1 - 0.15 12.2 36.9 0.2 11.8 0.7 7.3 3 3 5 8 8 8 0 Zinc ribbon domain UBZ_FAAP20 PF15750.5 KFM77226.1 - 0.48 10.4 21.9 7.9 6.5 0.2 7.0 8 0 0 8 8 8 0 Ubiquitin-binding zinc-finger zf-C2H2_2 PF12756.7 KFM77226.1 - 0.76 10.1 43.7 9.8 6.6 0.3 8.9 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.8 KFM77226.1 - 1.4 9.3 18.6 0.34 11.3 0.7 4.5 3 2 0 4 4 4 0 zinc-finger-containing domain FYDLN_acid PF09538.10 KFM77226.1 - 1.5 9.6 26.2 0.26 12.0 0.9 6.4 1 1 4 6 6 6 0 Protein of unknown function (FYDLN_acid) BolA PF01722.18 KFM77226.1 - 2.1 8.7 10.8 36 4.7 1.5 5.1 2 1 2 5 5 5 0 BolA-like protein zf-C2H2_11 PF16622.5 KFM77226.1 - 2.8 7.8 39.7 0.71 9.7 1.7 7.6 8 0 0 8 8 8 0 zinc-finger C2H2-type Endonuclease_7 PF02945.15 KFM77226.1 - 10 6.2 39.3 0.048 13.6 3.5 5.5 1 1 3 4 4 4 0 Recombination endonuclease VII DDE_3 PF13358.6 KFM77228.1 - 2e-16 60.1 0.1 2.2e-15 56.7 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM77228.1 - 1.4e-10 41.3 1.0 2.7e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Transposase PHTB1_C PF14728.6 KFM77230.1 - 7.4e-53 180.0 1.5 8.3e-53 179.8 1.5 1.0 1 0 0 1 1 1 1 PTHB1 C-terminus PHTB1_N PF14727.6 KFM77231.1 - 8.7e-43 147.2 0.0 9.9e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_N PF14727.6 KFM77232.1 - 4.2e-24 85.7 0.0 4.4e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_N PF14727.6 KFM77233.1 - 3.6e-34 118.8 0.0 4e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 PTHB1 N-terminus BofC_C PF08955.10 KFM77234.1 - 0.052 13.6 0.0 0.069 13.2 0.0 1.1 1 0 0 1 1 1 0 BofC C-terminal domain Phos_pyr_kin PF08543.12 KFM77235.1 - 3e-07 30.1 0.0 3.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KFM77235.1 - 0.00012 21.5 0.0 0.00012 21.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase AdenylateSensor PF16579.5 KFM77240.1 - 7.3e-19 68.4 1.1 1.9e-18 67.0 1.1 1.6 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase CDH PF02611.15 KFM77240.1 - 0.074 12.6 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase UPF0561 PF10573.9 KFM77240.1 - 0.084 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Pkinase PF00069.25 KFM77241.1 - 9.1e-78 261.3 0.0 1.1e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM77241.1 - 1e-44 152.8 0.0 1.3e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM77241.1 - 4.7e-08 32.7 0.0 1.5e-07 31.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KFM77241.1 - 7.3e-05 22.4 0.3 0.00012 21.7 0.3 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 KFM77241.1 - 0.0052 15.7 0.1 0.0073 15.2 0.1 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 KFM77241.1 - 0.007 15.4 0.3 0.0095 14.9 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM77241.1 - 0.0085 15.5 0.2 0.014 14.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM77241.1 - 0.034 14.1 0.2 0.11 12.4 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arm PF00514.23 KFM77242.1 - 3.1e-07 30.2 0.0 0.0073 16.3 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 KFM77242.1 - 0.024 13.7 0.2 0.038 13.1 0.2 1.2 1 0 0 1 1 1 0 Dopey, N-terminal RICTOR_N PF14664.6 KFM77242.1 - 0.027 13.5 0.2 0.038 13.0 0.2 1.3 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF3025 PF11227.8 KFM77243.1 - 0.072 12.9 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Sushi PF00084.20 KFM77244.1 - 2e-148 483.0 103.4 8.6e-12 45.5 0.3 16.2 16 0 0 16 16 16 16 Sushi repeat (SCR repeat) HRM PF02793.22 KFM77244.1 - 0.0011 19.2 70.4 0.16 12.3 0.8 13.2 12 2 2 14 14 14 7 Hormone receptor domain Tme5_EGF_like PF09064.10 KFM77244.1 - 1.4 8.9 6.9 17 5.4 0.3 5.0 3 0 0 3 3 3 0 Thrombomodulin like fifth domain, EGF-like Q_salvage PF10343.9 KFM77245.1 - 0.072 12.7 0.4 0.32 10.5 0.2 1.9 1 1 1 2 2 2 0 Potential Queuosine, Q, salvage protein family efThoc1 PF11957.8 KFM77245.1 - 0.12 11.0 0.2 0.17 10.5 0.2 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor ADP_ribosyl_GH PF03747.14 KFM77246.1 - 9.2e-42 143.7 0.0 1.2e-41 143.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase LRR_8 PF13855.6 KFM77246.1 - 9.9e-16 57.3 27.9 5e-09 35.8 2.1 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFM77246.1 - 3.1e-10 40.1 10.7 5.6e-05 23.4 0.5 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM77246.1 - 0.014 15.8 14.6 12 7.0 0.4 6.4 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KFM77246.1 - 0.034 14.2 12.4 6 7.2 0.1 6.2 6 0 0 6 6 6 0 Leucine Rich repeat Histone PF00125.24 KFM77247.1 - 7.4e-54 181.6 1.5 8.3e-54 181.5 1.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFM77247.1 - 7.4e-05 22.8 0.2 0.00016 21.8 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFM77247.1 - 8.5e-05 23.2 1.6 0.0001 22.9 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFM77247.1 - 0.00046 20.5 0.0 0.0007 19.9 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFM77247.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IML1 PF12257.8 KFM77248.1 - 1.2e-55 188.7 0.4 1.3e-55 188.6 0.4 1.0 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 IML1 PF12257.8 KFM77249.1 - 3.7e-24 85.3 0.0 4.6e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 Exo_endo_phos_2 PF14529.6 KFM77252.1 - 2.8e-21 75.6 0.0 5.2e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM77252.1 - 8e-05 22.3 1.0 0.0003 20.4 1.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DPPIV_rep PF18811.1 KFM77252.1 - 0.17 11.8 0.2 0.56 10.2 0.2 1.9 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region PCI PF01399.27 KFM77254.1 - 7.9e-21 74.5 1.1 2.9e-20 72.7 0.1 2.5 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KFM77254.1 - 6.4e-18 64.6 8.3 1.5e-17 63.4 8.3 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain PPR PF01535.20 KFM77254.1 - 0.022 15.0 0.8 6.4 7.3 0.0 3.9 3 1 1 4 4 4 0 PPR repeat SIX1_SD PF16878.5 KFM77254.1 - 0.036 14.6 0.1 0.036 14.6 0.1 2.6 3 1 1 4 4 4 0 Transcriptional regulator, SIX1, N-terminal SD domain PPR_1 PF12854.7 KFM77254.1 - 0.093 12.4 0.1 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 PPR repeat Tubulin_C PF03953.17 KFM77254.1 - 0.13 12.4 0.7 0.48 10.6 0.0 2.2 2 0 0 2 2 2 0 Tubulin C-terminal domain TPR_12 PF13424.6 KFM77254.1 - 0.84 10.0 3.1 16 5.9 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DDE_Tnp_1_7 PF13843.6 KFM77257.1 - 2.9e-59 201.1 0.1 3.6e-59 200.8 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 DUF2180 PF09947.9 KFM77257.1 - 0.026 14.5 1.5 0.057 13.4 1.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Tnp_zf-ribbon_2 PF13842.6 KFM77257.1 - 0.092 13.6 19.3 0.12 13.2 16.3 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF2797 PF10977.8 KFM77257.1 - 0.19 11.6 5.1 0.3 10.9 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) zf-B_box PF00643.24 KFM77257.1 - 0.93 9.7 5.9 2.1 8.6 5.9 1.5 1 0 0 1 1 1 0 B-box zinc finger Cadherin PF00028.17 KFM77258.1 - 2.4e-119 390.1 25.2 7e-20 71.3 0.1 8.2 8 0 0 8 8 8 8 Cadherin domain RET_CLD1 PF17756.1 KFM77258.1 - 4.3e-16 59.3 0.0 2.1e-06 28.0 0.0 7.0 7 1 0 7 7 7 3 RET Cadherin like domain 1 Cadherin_3 PF16184.5 KFM77258.1 - 3.8e-10 39.7 12.7 0.076 13.0 0.0 6.1 6 0 0 6 6 6 5 Cadherin-like Cadherin_pro PF08758.11 KFM77258.1 - 3.9e-05 23.7 0.0 0.023 14.9 0.0 4.3 5 0 0 5 5 5 1 Cadherin prodomain like Cadherin_2 PF08266.12 KFM77258.1 - 4.4e-05 23.2 0.0 4.8 7.1 0.0 4.9 4 0 0 4 4 4 2 Cadherin-like Glyco_hydro_17 PF00332.18 KFM77259.1 - 0.086 12.4 0.1 0.086 12.4 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 HTH_24 PF13412.6 KFM77260.1 - 0.032 13.8 0.3 0.33 10.6 0.2 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF4209 PF13910.6 KFM77260.1 - 0.1 12.8 0.1 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4209) UPF0239 PF06783.11 KFM77262.1 - 0.029 14.5 3.5 0.029 14.5 3.5 3.8 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0239) WBP-1 PF11669.8 KFM77262.1 - 3.2 8.4 5.1 0.72 10.5 0.1 2.3 2 1 1 3 3 3 0 WW domain-binding protein 1 ATP-synt_8 PF00895.20 KFM77262.1 - 7.1 7.2 0.0 7.1 7.2 0.0 3.1 3 1 0 3 3 3 0 ATP synthase protein 8 Ig_3 PF13927.6 KFM77263.1 - 4.2e-27 94.6 0.1 2e-13 50.7 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM77263.1 - 9.7e-24 83.3 0.0 1.1e-14 54.2 0.0 2.3 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM77263.1 - 3.4e-18 65.7 0.1 4.6e-10 39.7 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM77263.1 - 2.5e-16 59.6 0.0 7.4e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM77263.1 - 7.7e-11 42.1 0.2 6.9e-05 23.0 0.1 3.9 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM77263.1 - 2.7e-07 30.1 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM77263.1 - 7.7e-06 25.9 0.0 0.047 13.8 0.0 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM77263.1 - 0.00078 19.5 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFM77263.1 - 0.0022 18.3 0.0 1.9 8.9 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFM77263.1 - 0.012 16.0 0.0 1.9 8.9 0.0 2.5 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain fn3 PF00041.21 KFM77264.1 - 6e-14 52.2 0.1 1e-13 51.4 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain PRMT5 PF05185.16 KFM77267.1 - 2.2e-72 242.5 0.0 3.1e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KFM77267.1 - 1.7e-54 184.4 1.1 2.7e-54 183.7 1.1 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 KFM77267.1 - 2.9e-37 128.3 0.2 4.5e-37 127.6 0.2 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Met_10 PF02475.16 KFM77267.1 - 0.00018 21.4 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KFM77267.1 - 0.00024 21.8 0.0 0.00046 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFM77267.1 - 0.049 13.1 0.1 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase Methyltransf_31 PF13847.6 KFM77267.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain IF-2B PF01008.17 KFM77267.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family EBA-175_VI PF11556.8 KFM77270.1 - 0.18 12.2 4.0 0.2 12.0 4.0 1.4 1 1 0 1 1 1 0 Erythrocyte binding antigen 175 PI-PLC-X PF00388.19 KFM77271.1 - 9.1e-62 206.9 0.0 3.2e-60 201.9 0.0 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFM77271.1 - 1.4e-42 144.7 0.1 1.4e-42 144.7 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 KFM77271.1 - 7.5e-39 132.6 0.0 1.7e-38 131.4 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1154 PF06631.11 KFM77271.1 - 1.9e-15 56.6 10.8 5.4e-15 55.1 10.8 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1154) EF-hand_like PF09279.11 KFM77271.1 - 2.5e-10 40.7 3.5 7.9e-10 39.1 0.1 2.9 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFM77271.1 - 2.7e-07 30.8 0.0 6.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 KFM77271.1 - 0.047 13.6 0.1 0.17 11.9 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain Psb28 PF03912.14 KFM77271.1 - 0.094 13.0 0.1 0.92 9.8 0.0 2.5 2 0 0 2 2 2 0 Psb28 protein PLC-beta_C PF08703.10 KFM77272.1 - 1.2e-09 38.4 23.3 1.4e-09 38.2 23.3 1.0 1 0 0 1 1 1 1 PLC-beta C terminal Phasin PF05597.11 KFM77272.1 - 0.042 13.9 9.9 0.055 13.5 1.9 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tricorn_C1 PF14684.6 KFM77272.1 - 0.048 13.7 0.1 0.16 12.1 0.0 1.9 1 1 1 2 2 2 0 Tricorn protease C1 domain FAM184 PF15665.5 KFM77272.1 - 0.19 11.5 23.3 0.1 12.4 4.4 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Mitofilin PF09731.9 KFM77272.1 - 0.22 10.4 21.5 0.016 14.1 7.1 1.9 1 1 1 2 2 2 0 Mitochondrial inner membrane protein DUF445 PF04286.12 KFM77272.1 - 0.33 10.7 8.9 0.38 10.5 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2587 PF10759.9 KFM77272.1 - 0.37 10.3 5.6 0.16 11.5 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2587) HSP70 PF00012.20 KFM77272.1 - 2.5 6.2 10.9 3.2 5.8 10.9 1.0 1 0 0 1 1 1 0 Hsp70 protein Exonuc_VII_L PF02601.15 KFM77272.1 - 3.5 7.1 12.1 4.9 6.6 12.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KFM77272.1 - 6.1 5.6 10.9 7 5.4 10.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 KFM77272.1 - 9 6.4 8.5 14 5.7 4.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1154 PF06631.11 KFM77273.1 - 0.01 15.8 5.5 0.01 15.8 5.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1154) DUF2570 PF10828.8 KFM77273.1 - 0.13 12.1 5.6 0.26 11.1 5.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF763 PF05559.11 KFM77273.1 - 0.37 9.9 4.2 0.56 9.3 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) APG6_N PF17675.1 KFM77273.1 - 3.1 8.3 13.6 0.24 12.0 6.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region PI-PLC-Y PF00387.19 KFM77274.1 - 1.5e-12 47.9 0.0 2.1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-Y PF00387.19 KFM77275.1 - 4.1e-18 65.8 0.9 6.3e-18 65.2 0.9 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain CENP-B_dimeris PF09026.10 KFM77275.1 - 0.053 13.9 1.3 0.088 13.2 1.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nse5 PF08691.10 KFM77275.1 - 0.076 11.7 0.5 0.11 11.1 0.5 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 FAM176 PF14851.6 KFM77275.1 - 5.4 6.7 6.2 1.9 8.1 3.1 1.7 1 1 1 2 2 2 0 FAM176 family RT_RNaseH PF17917.1 KFM77276.1 - 2.5e-33 114.5 0.1 6e-33 113.3 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KFM77276.1 - 2.8e-33 113.9 0.1 8.7e-33 112.4 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM77276.1 - 8.2e-25 87.6 0.3 4.6e-24 85.2 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KFM77276.1 - 9.6e-20 71.0 0.0 2.2e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM77276.1 - 1.5e-15 57.1 0.6 4.1e-15 55.6 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVP PF00077.20 KFM77276.1 - 1e-06 29.0 0.0 3.1e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 KFM77276.1 - 0.0061 16.3 0.0 0.024 14.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 KFM77276.1 - 0.0072 16.4 0.9 0.015 15.3 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 KFM77276.1 - 0.06 13.9 0.0 0.23 12.0 0.0 2.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 KFM77276.1 - 0.071 13.4 0.3 0.2 11.9 0.3 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 KFM77276.1 - 0.093 13.4 0.0 0.57 10.9 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Alpha-amylase PF00128.24 KFM77277.1 - 4.4e-07 29.8 0.0 7.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain BAH PF01426.18 KFM77279.1 - 2.6e-11 43.4 2.5 1.6e-10 40.9 0.8 3.3 2 1 0 2 2 2 1 BAH domain HTH_Tnp_Tc3_2 PF01498.18 KFM77280.1 - 2e-16 60.0 2.2 3.7e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77280.1 - 7.3e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM77281.1 - 1.6e-16 60.4 0.1 3.1e-15 56.2 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM77281.1 - 1.4e-10 41.2 1.0 2.8e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase MULE PF10551.9 KFM77284.1 - 0.065 13.7 0.1 0.098 13.1 0.1 1.4 1 0 0 1 1 1 0 MULE transposase domain Myb_DNA-bind_5 PF13873.6 KFM77286.1 - 2.7e-05 24.2 1.5 2.7e-05 24.2 1.5 1.9 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain AAA_13 PF13166.6 KFM77286.1 - 0.00055 18.7 0.7 0.00061 18.6 0.7 1.0 1 0 0 1 1 1 1 AAA domain CLZ PF16526.5 KFM77286.1 - 0.00072 19.9 0.2 0.00072 19.9 0.2 2.2 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AflR PF08493.10 KFM77286.1 - 0.0022 17.5 0.1 0.0029 17.1 0.1 1.1 1 0 0 1 1 1 1 Aflatoxin regulatory protein DUF677 PF05055.12 KFM77286.1 - 0.0049 15.8 0.7 0.0064 15.4 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Baculo_PEP_C PF04513.12 KFM77286.1 - 0.0066 16.5 4.0 0.0099 15.9 4.0 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Med4 PF10018.9 KFM77286.1 - 0.039 13.6 0.7 0.058 13.1 0.6 1.4 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CENP-F_leu_zip PF10473.9 KFM77286.1 - 0.048 13.7 2.5 0.25 11.4 1.4 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliS PF02561.14 KFM77286.1 - 0.066 13.5 0.1 0.098 12.9 0.1 1.3 1 0 0 1 1 1 0 Flagellar protein FliS DUF4665 PF15679.5 KFM77286.1 - 0.12 13.1 2.4 0.28 11.8 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) COG2 PF06148.11 KFM77286.1 - 0.18 11.9 2.4 0.16 12.0 0.8 1.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DprA_WH PF17782.1 KFM77286.1 - 0.18 11.9 0.0 3.2 7.9 0.0 2.2 2 0 0 2 2 2 0 DprA winged helix domain IZUMO PF15005.6 KFM77286.1 - 0.18 12.3 0.9 0.53 10.8 1.1 1.8 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated CdvA PF18822.1 KFM77286.1 - 0.32 10.8 4.0 0.89 9.4 1.2 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain HTH_Tnp_Tc3_2 PF01498.18 KFM77288.1 - 4.3e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77288.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77288.1 - 1.9e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77288.1 - 0.0024 17.6 0.6 0.0071 16.1 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM77288.1 - 1.6 9.4 15.6 0.11 13.1 1.9 3.3 2 1 1 3 3 3 0 Homeodomain-like domain DUF4371 PF14291.6 KFM77289.1 - 2.5e-25 89.5 0.7 3.4e-25 89.1 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Phospholip_A2_3 PF09056.11 KFM77289.1 - 0.0077 16.9 1.8 1 10.0 0.1 2.6 2 0 0 2 2 2 2 Prokaryotic phospholipase A2 cNMP_binding PF00027.29 KFM77291.1 - 2.9e-17 62.5 0.0 5.7e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PPP5 PF08321.12 KFM77291.1 - 0.011 16.0 0.2 0.047 14.0 0.0 2.1 2 0 0 2 2 2 0 PPP5 TPR repeat region Glyco_hydro_42C PF08533.10 KFM77291.1 - 0.15 11.8 0.0 0.45 10.3 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain Ion_trans_2 PF07885.16 KFM77292.1 - 0.0018 18.2 4.0 0.0022 17.9 4.0 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFM77292.1 - 0.012 14.8 1.1 0.014 14.7 1.1 1.1 1 0 0 1 1 1 0 Ion transport protein Ion_trans PF00520.31 KFM77293.1 - 1.2e-09 37.8 0.8 1.7e-09 37.3 0.8 1.2 1 0 0 1 1 1 1 Ion transport protein RNF111_N PF15303.6 KFM77293.1 - 0.049 13.4 1.8 0.061 13.1 1.8 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus HTH_Tnp_Tc3_2 PF01498.18 KFM77294.1 - 2.2e-16 59.8 2.2 4.2e-16 59.0 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77294.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM77295.1 - 8.5e-16 58.0 6.5 1.6e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77295.1 - 1.3e-15 57.4 0.1 1.4e-14 54.1 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.6 KFM77295.1 - 9.2e-07 28.9 0.1 0.07 13.3 0.1 3.1 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 KFM77295.1 - 4.5e-06 26.3 0.1 0.13 12.1 0.0 4.0 4 0 0 4 4 4 2 Homeodomain-like domain HTH_29 PF13551.6 KFM77295.1 - 0.00075 19.5 2.0 0.055 13.5 0.2 3.1 3 0 0 3 3 3 1 Winged helix-turn helix HTH_7 PF02796.15 KFM77295.1 - 0.0019 18.2 0.0 0.37 10.9 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM77295.1 - 0.013 16.1 1.3 0.013 16.1 1.3 2.6 2 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM77296.1 - 2.5e-16 59.7 2.2 4.5e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77296.1 - 9.9e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5516 PF17637.2 KFM77296.1 - 0.16 11.8 0.4 0.97 9.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5516) Sarcoglycan_1 PF04790.13 KFM77297.1 - 5.6e-49 166.8 0.8 6.8e-49 166.6 0.8 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFM77297.1 - 0.12 12.2 0.2 23 4.8 0.0 3.0 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) DUF4371 PF14291.6 KFM77298.1 - 4.7e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) CRISPR_Cas2 PF09827.9 KFM77298.1 - 0.31 11.3 3.0 4.8 7.4 0.4 3.3 3 0 0 3 3 3 0 CRISPR associated protein Cas2 XPG_N PF00752.17 KFM77300.1 - 1.5e-22 79.9 0.0 1.9e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 XPG N-terminal domain TPR_2 PF07719.17 KFM77300.1 - 0.0094 16.0 0.0 0.035 14.2 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM77300.1 - 0.1 12.5 0.1 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TMEM132D_C PF15706.5 KFM77302.1 - 0.056 13.2 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term HTH_Tnp_Tc3_2 PF01498.18 KFM77303.1 - 2.6e-16 59.6 2.2 4.7e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM77303.1 - 1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Acyl_transf_3 PF01757.22 KFM77304.1 - 1.4e-08 34.2 37.4 1.4e-08 34.2 37.4 2.1 1 1 0 1 1 1 1 Acyltransferase family Tnp_P_element PF12017.8 KFM77306.1 - 0.00019 20.9 0.0 0.00024 20.6 0.0 1.1 1 0 0 1 1 1 1 Transposase protein IATP PF04568.12 KFM77307.1 - 1.2e-22 80.1 2.0 1.3e-22 80.1 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP tRNA-synt_2 PF00152.20 KFM77308.1 - 5.7e-29 101.2 0.0 6.3e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KFM77308.1 - 0.048 13.1 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 KFM77309.1 - 6e-15 55.1 0.1 8.3e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFM77309.1 - 9.4e-10 38.4 0.0 2.6e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Vitellogenin_N PF01347.22 KFM77310.1 - 5.9e-41 140.6 0.0 8.8e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 KFM77310.1 - 2.5e-29 102.5 6.3 5.7e-29 101.3 6.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) DUF1081 PF06448.11 KFM77310.1 - 0.00011 22.5 0.5 0.0021 18.4 0.0 3.3 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1081) Melibiase_2_C PF17450.2 KFM77310.1 - 0.067 13.4 0.1 1.7 8.9 0.0 2.8 2 0 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain DUF1241 PF06840.11 KFM77310.1 - 0.075 12.7 0.0 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) STAR_dimer PF16544.5 KFM77311.1 - 3.1e-26 90.7 0.5 6e-26 89.8 0.5 1.5 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 KFM77311.1 - 7e-07 29.0 0.1 1.3e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 KH domain GBR2_CC PF18455.1 KFM77312.1 - 0.046 13.8 0.5 0.09 12.9 0.0 1.7 2 0 0 2 2 2 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain HOOK PF05622.12 KFM77312.1 - 0.098 10.8 0.1 0.11 10.7 0.1 1.0 1 0 0 1 1 1 0 HOOK protein Curto_V3 PF07436.11 KFM77312.1 - 0.16 12.4 2.5 2.4 8.6 0.4 2.4 1 1 1 2 2 2 0 Curtovirus V3 protein Peptidase_M16 PF00675.20 KFM77313.1 - 0.095 12.7 0.4 0.097 12.6 0.4 1.1 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) BTB PF00651.31 KFM77314.1 - 6.7e-12 45.6 0.2 1.7e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Slx4 PF09494.10 KFM77315.1 - 3.2e-14 52.6 0.2 8e-14 51.3 0.2 1.8 1 0 0 1 1 1 1 Slx4 endonuclease I-set PF07679.16 KFM77318.1 - 8.9e-38 128.2 0.0 1.2e-12 47.8 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM77318.1 - 7.7e-36 122.6 0.0 5.2e-13 49.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM77318.1 - 2.2e-25 88.8 0.0 1.3e-09 38.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM77318.1 - 3.2e-17 62.5 0.0 0.00013 22.1 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM77318.1 - 1.5e-12 47.6 7.2 0.00039 20.6 0.1 5.4 3 3 1 4 4 4 3 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM77318.1 - 2e-08 34.5 0.9 0.068 13.6 0.0 4.9 3 2 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM77318.1 - 3.9e-06 26.8 0.0 0.18 11.9 0.0 3.4 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM77318.1 - 5.9e-05 22.6 0.0 0.071 12.7 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFM77318.1 - 6.3e-05 23.2 6.6 0.17 12.2 0.4 4.4 3 3 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_3 PF13927.6 KFM77319.1 - 0.00014 22.3 0.1 0.0016 19.0 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM77319.1 - 0.021 14.9 0.1 0.099 12.7 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM77319.1 - 0.063 13.6 0.0 0.16 12.4 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin domain Pyr_redox_2 PF07992.14 KFM77320.1 - 2.2e-57 194.5 0.0 3e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM77320.1 - 3.5e-18 65.9 0.3 1.5e-12 47.9 0.3 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM77320.1 - 9.6e-17 61.2 0.6 3.4e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KFM77320.1 - 1.4e-16 60.2 0.0 3.5e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain HI0933_like PF03486.14 KFM77320.1 - 3.6e-07 29.2 0.2 0.0017 17.1 0.1 2.9 3 0 0 3 3 3 2 HI0933-like protein Reductase_C PF14759.6 KFM77320.1 - 7.6e-06 26.4 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 KFM77320.1 - 6.4e-05 22.8 0.0 0.00023 21.0 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain FAD_binding_2 PF00890.24 KFM77320.1 - 0.0018 17.4 0.1 0.0049 16.0 0.0 1.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KFM77320.1 - 0.0024 18.1 0.1 0.0072 16.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM77320.1 - 0.0033 17.0 0.1 0.84 9.2 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KFM77320.1 - 0.0081 16.6 0.0 1.2 9.6 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 KFM77320.1 - 0.014 14.3 0.1 0.092 11.6 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 KFM77320.1 - 0.023 14.9 0.1 2 8.7 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain FAD_binding_3 PF01494.19 KFM77320.1 - 0.22 10.7 0.1 0.47 9.7 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain DIM1 PF02966.16 KFM77321.1 - 9.8e-62 206.6 0.2 1.1e-61 206.4 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KFM77321.1 - 3.5e-07 30.2 0.0 4.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFM77321.1 - 0.0082 16.4 0.2 0.013 15.8 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 KFM77321.1 - 0.044 13.7 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KFM77321.1 - 0.081 13.1 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Rgp1 PF08737.10 KFM77322.1 - 2.7e-45 155.3 3.6 6.1e-24 85.0 0.8 2.9 2 1 1 3 3 3 2 Rgp1 Perilipin PF03036.16 KFM77323.1 - 4.7e-21 75.3 0.0 8e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Perilipin family TPR_2 PF07719.17 KFM77324.1 - 1.9e-36 121.2 36.7 6.8e-06 25.8 0.4 18.2 19 1 1 20 20 18 10 Tetratricopeptide repeat TPR_1 PF00515.28 KFM77324.1 - 1.5e-30 103.7 32.3 4.4e-05 23.1 0.2 16.6 17 1 1 18 18 18 8 Tetratricopeptide repeat TPR_19 PF14559.6 KFM77324.1 - 6.8e-28 97.0 17.6 7.9e-05 23.1 0.0 13.1 13 2 2 15 15 14 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFM77324.1 - 9.1e-20 69.7 7.3 0.0088 16.8 0.1 13.8 12 3 4 16 16 12 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM77324.1 - 2.7e-17 62.8 14.2 0.11 12.8 0.0 12.8 12 2 1 13 13 12 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM77324.1 - 1.1e-16 60.3 23.2 0.00015 21.4 0.4 13.0 13 2 2 15 15 15 4 TPR repeat TPR_16 PF13432.6 KFM77324.1 - 4.3e-16 59.3 3.5 0.00034 21.2 0.2 10.1 10 1 2 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFM77324.1 - 1.8e-15 56.1 26.0 0.0041 17.4 0.2 14.5 15 1 0 15 15 14 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM77324.1 - 2.8e-13 48.9 54.5 0.0016 18.5 0.3 16.7 21 0 0 21 21 18 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM77324.1 - 3.5e-09 36.8 41.6 0.0014 18.8 0.2 11.1 8 3 4 12 12 11 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFM77324.1 - 2e-08 34.2 0.0 0.17 12.0 0.0 6.2 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFM77324.1 - 5e-06 25.9 13.2 0.7 9.0 3.4 6.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TOM20_plant PF06552.12 KFM77324.1 - 5.5e-05 23.0 5.9 0.05 13.3 0.1 4.5 4 0 0 4 4 3 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_MalT PF17874.1 KFM77324.1 - 9e-05 22.0 1.3 1.5 8.1 0.0 5.1 5 1 0 5 5 5 2 MalT-like TPR region TPR_7 PF13176.6 KFM77324.1 - 0.00028 20.7 14.3 4.6 7.5 0.0 9.1 12 0 0 12 12 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM77324.1 - 0.00076 19.3 9.3 15 5.6 0.0 8.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFM77324.1 - 0.011 16.1 5.9 21 5.5 0.0 6.3 6 1 1 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM77324.1 - 0.019 15.6 22.6 14 6.6 0.2 10.9 11 0 0 11 11 10 0 Tetratricopeptide repeat PPR PF01535.20 KFM77324.1 - 0.028 14.7 1.7 2.9 8.4 0.1 4.1 3 0 0 3 3 2 0 PPR repeat BLF1 PF17752.1 KFM77324.1 - 0.056 12.7 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Burkholderia lethal factor 1 Alkyl_sulf_dimr PF14863.6 KFM77324.1 - 0.062 13.8 5.1 1.7 9.1 0.4 4.6 5 1 0 5 5 4 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 KFM77324.1 - 0.069 13.2 8.6 0.38 10.9 0.1 4.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 KFM77324.1 - 0.078 12.0 15.7 0.48 9.4 0.1 6.5 7 1 2 9 9 9 0 ChAPs (Chs5p-Arf1p-binding proteins) YfiO PF13525.6 KFM77324.1 - 0.2 11.3 4.6 0.25 11.0 0.2 3.1 3 0 0 3 3 3 0 Outer membrane lipoprotein TPR_3 PF07720.12 KFM77324.1 - 0.22 11.6 4.2 1.6 8.8 1.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Anticodon_1 PF08264.13 KFM77324.1 - 0.74 9.8 3.5 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 Anticodon-binding domain of tRNA HTH_Tnp_Tc3_2 PF01498.18 KFM77325.1 - 4.4e-16 58.9 3.4 5.3e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77325.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77325.1 - 1.9e-07 30.7 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77325.1 - 0.0025 17.6 0.6 0.0071 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM77325.1 - 2.1 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain KH_1 PF00013.29 KFM77326.1 - 1.2e-26 92.3 1.6 2.5e-14 52.8 0.1 2.3 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 KFM77326.1 - 9.9e-10 38.1 10.7 1.6e-09 37.5 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM77326.1 - 4.1e-05 23.3 10.4 8.3e-05 22.4 10.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFM77326.1 - 9.7e-05 22.6 11.2 0.00018 21.8 11.2 1.4 1 0 0 1 1 1 1 Ring finger domain KH_2 PF07650.17 KFM77326.1 - 0.00071 19.3 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 1 KH domain zf-C3HC4 PF00097.25 KFM77326.1 - 0.00087 19.1 11.3 0.0017 18.2 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_4 PF13083.6 KFM77326.1 - 0.0012 18.6 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 2 KH domain zf-C3HC4_4 PF15227.6 KFM77326.1 - 0.085 13.0 11.7 0.29 11.3 11.0 2.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFM77326.1 - 0.22 11.4 4.3 0.53 10.2 4.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFM77326.1 - 0.45 10.4 10.9 2 8.3 10.9 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KFM77326.1 - 1.1 9.4 6.1 2.5 8.2 6.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Aminotran_1_2 PF00155.21 KFM77327.1 - 1.2e-68 231.9 0.0 1.6e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFM77327.1 - 2.7e-06 26.2 0.0 4.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFM77327.1 - 7.5e-06 25.1 0.0 1.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.21 KFM77327.1 - 0.0027 16.4 0.0 0.0039 15.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 KFM77327.1 - 0.016 14.5 0.0 0.16 11.2 0.0 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Alba PF01918.21 KFM77328.1 - 1.5e-14 53.6 0.3 3e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 Alba Peptidase_C3 PF00548.20 KFM77328.1 - 0.059 13.3 0.2 0.1 12.5 0.2 1.4 1 1 0 1 1 1 0 3C cysteine protease (picornain 3C) zf-MIZ PF02891.20 KFM77329.1 - 1.7e-12 46.9 0.3 2.6e-12 46.3 0.3 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger IQ PF00612.27 KFM77330.1 - 0.00019 20.9 0.1 0.00032 20.2 0.1 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif Kelch_1 PF01344.25 KFM77331.1 - 0.0002 20.9 4.0 0.049 13.2 0.2 2.0 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 KFM77331.1 - 0.0022 18.3 0.1 0.0029 17.8 0.1 1.2 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM77331.1 - 0.007 16.6 0.8 0.3 11.4 0.0 2.0 1 1 1 2 2 2 2 Kelch motif Kelch_5 PF13854.6 KFM77331.1 - 0.44 10.6 2.0 0.62 10.1 0.7 1.7 2 0 0 2 2 2 0 Kelch motif RNF220 PF15926.5 KFM77332.1 - 1.2e-33 116.8 5.2 3.4e-33 115.3 5.2 1.7 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 Ion_trans PF00520.31 KFM77334.1 - 2.8e-19 69.3 0.1 3e-19 69.2 0.1 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KFM77335.1 - 2.4e-29 102.3 4.0 2.9e-29 102.0 4.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KFM77336.1 - 1.5e-11 44.0 1.8 1.8e-11 43.8 1.8 1.1 1 0 0 1 1 1 1 Ion transport protein YwhD PF08741.10 KFM77336.1 - 0.14 11.8 0.3 0.22 11.2 0.3 1.3 1 0 0 1 1 1 0 YwhD family Ion_trans PF00520.31 KFM77337.1 - 2.2e-07 30.4 1.5 2.2e-07 30.4 1.5 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KFM77338.1 - 0.0028 16.9 4.6 0.0032 16.7 4.6 1.1 1 0 0 1 1 1 1 Ion transport protein TraQ PF09679.10 KFM77338.1 - 0.077 12.9 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF1344 PF07076.11 KFM77340.1 - 0.026 14.4 0.4 0.077 12.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Tho1_MOS11_C PF18592.1 KFM77340.1 - 3.4 7.5 6.1 0.67 9.8 1.2 2.5 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Barstar PF01337.18 KFM77341.1 - 0.057 13.4 0.0 0.059 13.4 0.0 1.0 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Fibrinogen_C PF00147.18 KFM77343.1 - 6.5e-60 202.7 10.1 8.2e-60 202.3 10.1 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 KFM77344.1 - 1.2e-59 201.8 8.2 1.4e-59 201.5 8.2 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF5641 PF18701.1 KFM77345.1 - 2.4e-20 72.5 0.8 4.9e-20 71.5 0.8 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1758 PF05585.12 KFM77345.1 - 9.6e-07 28.7 0.2 1.9e-06 27.7 0.2 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Fibrinogen_C PF00147.18 KFM77346.1 - 6e-59 199.5 6.5 7.3e-59 199.2 6.5 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 KFM77347.1 - 5.9e-60 202.8 6.2 6.7e-60 202.6 6.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Peptidase_M24_C PF16188.5 KFM77348.1 - 0.053 13.6 0.6 0.081 13.0 0.6 1.4 1 1 0 1 1 1 0 C-terminal region of peptidase_M24 V-set PF07686.17 KFM77349.1 - 7.3e-06 26.1 0.0 8.4e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFM77349.1 - 0.00013 22.0 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM77349.1 - 0.00013 22.1 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM77349.1 - 0.015 15.9 0.0 0.025 15.2 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin domain HTH_Tnp_Tc3_2 PF01498.18 KFM77350.1 - 4.3e-16 58.9 3.4 5.2e-16 58.6 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77350.1 - 1.1e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77350.1 - 1.8e-07 30.8 1.2 6.6e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77350.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM77350.1 - 2 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_IS1595 PF12762.7 KFM77351.1 - 3.6e-08 33.6 0.0 5.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain 7tm_1 PF00001.21 KFM77352.1 - 3.3e-12 46.3 0.2 3.7e-12 46.1 0.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HTH_Tnp_Tc3_2 PF01498.18 KFM77353.1 - 4.1e-16 59.0 3.4 5.2e-16 58.7 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77353.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM77353.1 - 1.8e-07 30.8 1.2 6.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM77353.1 - 0.0024 17.6 0.6 0.007 16.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM77353.1 - 0.024 14.8 0.4 0.083 13.0 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KFM77353.1 - 1.9 9.1 15.6 0.11 13.1 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Collagen PF01391.18 KFM77354.1 - 1e-53 178.9 168.7 7.6e-11 41.6 26.2 7.3 2 2 4 6 6 6 6 Collagen triple helix repeat (20 copies) Laminin_G_2 PF02210.24 KFM77354.1 - 0.0096 16.5 0.0 0.014 15.9 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM77354.1 - 0.017 15.4 0.0 0.044 14.0 0.0 1.6 2 0 0 2 2 2 0 Laminin G domain FAM195 PF14799.6 KFM77355.1 - 3.3e-17 62.7 0.0 4.8e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 FAM195 family Pkinase PF00069.25 KFM77356.1 - 1.6e-70 237.5 0.1 1.8e-70 237.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM77356.1 - 2.7e-46 158.0 0.1 3.2e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM77356.1 - 5.8e-08 32.4 0.0 1e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM77356.1 - 1.4e-05 24.1 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM77356.1 - 0.00013 21.9 0.1 0.022 14.7 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFM77356.1 - 0.0036 16.9 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFM77356.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1340 PF07067.11 KFM77359.1 - 0.057 12.8 0.1 0.063 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) U71 PF17474.2 KFM77359.1 - 2.2 8.3 8.4 4.7 7.2 0.8 2.5 2 0 0 2 2 2 0 Tegument protein UL11 homolog DEK_C PF08766.11 KFM77360.1 - 0.00068 19.5 1.1 0.0016 18.3 0.4 2.0 2 0 0 2 2 2 1 DEK C terminal domain SUA5 PF03481.13 KFM77360.1 - 0.13 12.9 0.1 0.34 11.5 0.1 1.7 1 1 0 1 1 1 0 Putative GTP-binding controlling metal-binding ubiquitin PF00240.23 KFM77361.1 - 1.3e-11 44.1 0.0 2.8e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KFM77361.1 - 0.07 13.6 0.0 0.24 11.9 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Ribosomal_S27 PF01599.19 KFM77361.1 - 0.84 9.8 5.1 7.6 6.8 0.4 2.4 1 1 1 2 2 2 0 Ribosomal protein S27a FHA PF00498.26 KFM77362.1 - 3.4e-17 62.6 0.0 8.3e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM77362.1 - 0.002 18.4 0.0 0.014 15.7 0.0 2.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Laminin_II PF06009.12 KFM77362.1 - 0.017 15.2 7.2 0.017 15.2 7.2 6.2 3 1 3 6 6 6 0 Laminin Domain II Pox_A_type_inc PF04508.12 KFM77362.1 - 0.071 13.0 15.0 0.91 9.5 0.9 5.6 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat MFS_1 PF07690.16 KFM77364.1 - 3.7e-23 82.0 29.0 8.4e-16 57.8 6.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily PIRT PF15099.6 KFM77364.1 - 0.0085 15.7 1.6 3.4 7.3 0.0 3.0 3 0 0 3 3 3 2 Phosphoinositide-interacting protein family QCR10 PF09796.9 KFM77364.1 - 0.057 13.5 1.8 6.7 6.9 0.1 2.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Sulfotransfer_3 PF13469.6 KFM77365.1 - 1.9e-12 48.1 0.0 3.7e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM77365.1 - 0.007 15.9 0.1 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase domain DUF659 PF04937.15 KFM77368.1 - 0.0045 16.8 0.6 0.0096 15.8 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM77368.1 - 0.0097 15.6 0.1 0.046 13.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM77368.1 - 0.016 15.0 0.1 0.25 11.2 0.1 2.8 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region UPF0113_N PF17833.1 KFM77369.1 - 4.8e-10 39.9 0.2 8.5e-10 39.1 0.2 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KFM77369.1 - 2e-05 24.8 0.0 3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain zf-met PF12874.7 KFM77369.1 - 0.07 13.5 0.2 0.26 11.7 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type BTB PF00651.31 KFM77372.1 - 2.2e-18 66.5 0.9 5.4e-18 65.2 0.9 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM77372.1 - 0.089 12.9 0.0 7.3 6.7 0.0 2.7 2 0 0 2 2 2 0 BTB And C-terminal Kelch FRB_dom PF08771.11 KFM77373.1 - 0.0032 17.8 0.1 0.0039 17.6 0.1 1.1 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain GNAT_C PF18164.1 KFM77373.1 - 0.0082 15.9 0.3 0.069 12.9 0.1 1.9 1 1 1 2 2 2 1 GNAT-like C-terminal domain Herpes_UL92 PF03048.14 KFM77373.1 - 0.018 14.8 0.1 0.02 14.6 0.1 1.0 1 0 0 1 1 1 0 UL92 family CRM1_C PF08767.11 KFM77373.1 - 0.043 13.0 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 CRM1 C terminal DUF3018 PF11455.8 KFM77374.1 - 0.049 13.6 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) RNase_P_Rpp14 PF01900.19 KFM77376.1 - 3.4e-21 75.4 0.1 5.4e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family RNase_H PF00075.24 KFM77377.1 - 4e-14 53.0 0.0 5.4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM77377.1 - 0.00029 20.7 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like DUF1651 PF07864.11 KFM77378.1 - 0.067 13.6 0.0 0.61 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) Coatomer_g_Cpla PF16381.5 KFM77378.1 - 0.096 12.8 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform Peptidase_M13_N PF05649.13 KFM77382.1 - 4.7e-116 388.6 0.0 5.9e-116 388.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM77382.1 - 6.8e-62 208.7 1.0 6.8e-62 208.7 1.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 Orbi_VP2 PF00898.17 KFM77382.1 - 0.13 10.0 0.2 0.2 9.4 0.2 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 FancD2 PF14631.6 KFM77383.1 - 3e-178 594.9 23.5 2.9e-130 435.9 11.2 2.0 1 1 1 2 2 2 2 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 KFM77383.1 - 2.5e-06 27.9 0.1 1.6e-05 25.2 0.1 2.4 1 1 0 1 1 1 1 FANCI solenoid 2 DUF4746 PF15928.5 KFM77383.1 - 0.014 14.9 0.4 0.025 14.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FancD2 PF14631.6 KFM77384.1 - 7.1e-18 63.5 1.1 7.5e-18 63.4 1.1 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease FancD2 PF14631.6 KFM77385.1 - 1e-42 145.9 0.4 1.2e-42 145.7 0.4 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease Carb_anhydrase PF00194.21 KFM77386.1 - 1.4e-76 257.4 0.0 1.6e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DHHC PF01529.20 KFM77387.1 - 3e-36 124.5 13.8 3e-36 124.5 13.8 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF1218 PF06749.12 KFM77387.1 - 3.3 8.3 16.1 0.58 10.7 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Aa_trans PF01490.18 KFM77388.1 - 6.2e-53 180.0 25.2 7.6e-53 179.7 25.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM77388.1 - 4.6e-05 22.6 22.5 0.00024 20.3 22.5 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3918 PF13056.6 KFM77388.1 - 0.087 12.5 0.3 17 5.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) DDE_Tnp_1_7 PF13843.6 KFM77390.1 - 2.4e-77 260.6 4.3 2.9e-77 260.3 4.3 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM77390.1 - 0.0021 18.8 6.1 0.0064 17.3 6.1 1.8 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon DDE_Tnp_1 PF01609.21 KFM77390.1 - 0.0065 16.1 0.2 0.09 12.4 0.0 2.4 2 0 0 2 2 2 1 Transposase DDE domain DUF4070 PF13282.6 KFM77390.1 - 0.1 12.7 3.6 0.15 12.2 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4070) DnaJ PF00226.31 KFM77392.1 - 2e-13 50.2 0.1 3.4e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain LAX PF15681.5 KFM77392.1 - 0.045 12.6 0.1 0.049 12.5 0.1 1.0 1 0 0 1 1 1 0 Lymphocyte activation family X DUF1977 PF09320.11 KFM77393.1 - 8e-13 48.6 1.0 1.5e-12 47.7 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Globin PF00042.22 KFM77394.1 - 3.5e-09 37.2 0.0 3.9e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Globin DUF2478 PF10649.9 KFM77394.1 - 0.046 13.3 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Thioesterase PF00975.20 KFM77395.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 KFM77395.1 - 0.016 14.5 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PHC2_SAM_assoc PF16616.5 KFM77395.1 - 1.8 9.4 13.1 0.042 14.7 4.0 2.7 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 ThiS-like PF14453.6 KFM77396.1 - 0.072 13.1 0.1 0.09 12.8 0.1 1.2 1 0 0 1 1 1 0 ThiS-like ubiquitin Tnp_zf-ribbon_2 PF13842.6 KFM77396.1 - 0.076 13.8 2.2 0.076 13.8 2.2 1.7 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon SNF PF00209.18 KFM77397.1 - 1.7e-58 198.6 5.1 1.9e-58 198.5 5.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family ABC_export PF16962.5 KFM77397.1 - 0.0048 15.4 2.8 0.37 9.2 0.1 2.0 2 0 0 2 2 2 2 Putative ABC exporter FtsX PF02687.21 KFM77397.1 - 0.11 13.0 3.9 5 7.7 0.1 2.4 2 0 0 2 2 2 0 FtsX-like permease family TssN PF17555.2 KFM77397.1 - 0.14 11.5 0.1 0.14 11.5 0.1 1.9 2 1 0 2 2 2 0 Type VI secretion system, TssN PMP22_Claudin PF00822.20 KFM77397.1 - 0.15 11.9 2.5 1.6 8.5 0.4 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family SNF PF00209.18 KFM77398.1 - 3.6e-55 187.7 7.6 4.1e-55 187.5 7.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Fasciclin PF02469.22 KFM77399.1 - 1.5e-36 125.4 0.0 9.6e-19 67.9 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain DUF211 PF02680.14 KFM77399.1 - 0.013 15.7 0.8 5.8 7.2 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 PSRP-3_Ycf65 PF04839.13 KFM77399.1 - 0.16 12.2 0.1 0.44 10.8 0.1 1.7 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) 7tm_6 PF02949.20 KFM77401.1 - 0.0058 15.7 0.2 0.62 9.1 0.1 2.0 1 1 1 2 2 2 2 7tm Odorant receptor I_LWEQ PF01608.17 KFM77401.1 - 0.012 15.9 0.1 0.015 15.5 0.1 1.1 1 0 0 1 1 1 0 I/LWEQ domain tRNA_bind PF01588.20 KFM77402.1 - 0.043 13.9 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative tRNA binding domain 7tm_1 PF00001.21 KFM77403.1 - 1.1e-36 126.5 2.6 1.4e-36 126.2 2.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM77403.1 - 1.2e-05 24.8 0.4 1.5e-05 24.5 0.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM77403.1 - 0.00013 21.7 0.2 0.00016 21.4 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KFM77404.1 - 3.5e-08 33.1 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3018 PF11455.8 KFM77404.1 - 0.066 13.2 0.1 0.088 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) DUF1011 PF06237.12 KFM77405.1 - 1.1e-29 102.7 5.1 1.1e-29 102.7 5.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1011) PHD PF00628.29 KFM77407.1 - 6.1e-10 38.8 9.7 1.1e-09 38.1 9.7 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KFM77407.1 - 0.00029 20.6 2.7 0.00029 20.6 2.7 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KFM77407.1 - 0.0046 17.0 9.8 0.027 14.6 9.8 2.2 1 1 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KFM77407.1 - 0.009 15.9 3.3 0.009 15.9 3.3 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 KFM77407.1 - 0.028 14.0 7.1 0.11 12.1 7.0 1.9 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KFM77407.1 - 0.14 11.8 7.8 0.36 10.4 7.8 1.8 1 1 0 1 1 1 0 PHD-finger Cytochrom_c3_2 PF14537.6 KFM77407.1 - 0.27 11.7 10.1 2.1 8.9 7.3 2.7 1 1 1 2 2 2 0 Cytochrome c3 zf-RRPl_C4 PF17026.5 KFM77407.1 - 1.8 8.7 7.9 6.2 7.0 7.9 1.9 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Zf_RING PF16744.5 KFM77407.1 - 2.6 8.2 11.0 23 5.2 10.4 2.4 1 1 1 2 2 2 0 KIAA1045 RING finger zf-RING_9 PF13901.6 KFM77407.1 - 6.2 6.7 13.7 0.38 10.7 8.0 1.9 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon ER PF01133.17 KFM77408.1 - 2.4e-43 146.1 0.6 2.7e-43 146.0 0.6 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary PAS_12 PF18095.1 KFM77408.1 - 0.061 13.0 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain Homeodomain PF00046.29 KFM77410.1 - 2.7e-19 68.8 2.3 4.6e-19 68.0 2.3 1.4 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc3_2 PF01498.18 KFM77413.1 - 2.9e-21 75.5 5.9 1.7e-16 60.2 1.0 2.4 2 0 0 2 2 2 2 Transposase DDE_3 PF13358.6 KFM77413.1 - 3.5e-13 49.5 0.0 6.7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM77413.1 - 5.9e-06 26.8 15.6 0.0084 16.7 1.5 3.9 3 1 1 4 4 4 2 Homeodomain-like domain HTH_3 PF01381.22 KFM77413.1 - 0.015 15.3 0.7 0.56 10.3 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix HTH_Crp_2 PF13545.6 KFM77413.1 - 0.08 12.9 1.9 0.34 10.9 0.1 2.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_26 PF13443.6 KFM77413.1 - 0.19 12.2 2.1 18 5.8 0.2 3.3 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain CHCH PF06747.13 KFM77414.1 - 1.3e-06 28.4 4.7 1.9e-06 27.8 4.7 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KFM77414.1 - 0.014 15.4 5.0 0.025 14.6 5.0 1.4 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KFM77414.1 - 0.033 14.5 5.0 0.091 13.1 5.0 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 EST1_DNA_bind PF10373.9 KFM77415.1 - 3.4e-16 59.6 0.8 7e-16 58.5 0.8 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Pkinase_Tyr PF07714.17 KFM77417.1 - 9e-51 172.6 0.0 1.3e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM77417.1 - 1.5e-29 103.2 0.0 2.5e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HOIP-UBA PF16678.5 KFM77419.1 - 1.2e-52 177.9 3.3 7.9e-52 175.3 0.3 3.2 2 0 0 2 2 2 1 HOIP UBA domain pair E3_UbLigase_RBR PF18091.1 KFM77419.1 - 8.9e-32 109.1 0.5 9.9e-31 105.7 0.2 3.1 2 0 0 2 2 2 1 E3 Ubiquitin Ligase RBR C-terminal domain IBR PF01485.21 KFM77419.1 - 1.2e-09 38.2 21.6 1.7e-09 37.8 5.2 4.2 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain UBA PF00627.31 KFM77419.1 - 0.0038 17.1 2.7 0.099 12.6 0.5 3.6 4 0 0 4 4 4 1 UBA/TS-N domain zf-H2C2_5 PF13909.6 KFM77420.1 - 6.6e-06 25.8 50.1 0.00017 21.2 5.5 7.6 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFM77420.1 - 0.057 13.9 0.6 0.057 13.9 0.6 11.9 13 2 1 14 14 14 0 Zinc-finger double domain Miff PF05644.11 KFM77422.1 - 2.6e-30 106.0 7.3 6e-22 78.6 0.3 2.0 1 1 1 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff TSC22 PF01166.18 KFM77422.1 - 0.066 13.5 0.4 0.19 12.1 0.3 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Trypsin PF00089.26 KFM77424.1 - 2.2e-55 187.9 0.1 4.4e-55 186.9 0.0 1.5 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 KFM77424.1 - 2.4e-05 25.3 0.0 6e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM77424.1 - 4.1e-05 23.9 2.0 0.00034 21.0 0.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1986) EamA PF00892.20 KFM77425.1 - 1.6e-20 73.6 35.4 3.7e-15 56.3 11.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family HKR_ArcB_TM PF18415.1 KFM77425.1 - 0.072 13.9 0.4 0.072 13.9 0.4 3.2 4 1 0 4 4 4 0 Histidine kinase receptor ArcB trans-membrane domain DUF423 PF04241.15 KFM77425.1 - 0.35 11.1 10.7 5.4 7.3 1.8 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF423) Metalloenzyme PF01676.18 KFM77426.1 - 8.5e-81 271.0 0.1 9.7e-81 270.8 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 KFM77426.1 - 5.9e-73 244.9 0.0 8.5e-73 244.4 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 KFM77426.1 - 1.6e-06 28.0 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFM77426.1 - 4.9e-06 26.1 0.0 1.4e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.20 KFM77426.1 - 0.0024 16.9 0.0 0.0049 15.9 0.0 1.5 1 0 0 1 1 1 1 Alkaline phosphatase PglZ PF08665.12 KFM77426.1 - 0.092 12.8 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 PglZ domain SM-ATX PF14438.6 KFM77427.1 - 1e-16 60.8 0.3 2.4e-16 59.6 0.3 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 KFM77427.1 - 6.4e-16 58.7 0.3 6.4e-16 58.7 0.3 2.0 2 0 0 2 2 2 1 LsmAD domain PAM2 PF07145.15 KFM77427.1 - 1e-06 28.0 13.2 0.00088 18.8 1.6 3.8 2 1 1 3 3 3 2 Ataxin-2 C-terminal region LSM14 PF12701.7 KFM77427.1 - 0.00042 20.3 0.1 0.0011 19.0 0.1 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain Transmemb_17 PF09799.9 KFM77429.1 - 4.1e-25 88.4 6.3 4.3e-25 88.4 6.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein Death PF00531.22 KFM77430.1 - 3.2e-10 40.0 0.7 7.8e-10 38.8 0.7 1.6 1 0 0 1 1 1 1 Death domain DED PF01335.21 KFM77430.1 - 0.00035 20.8 0.7 0.00089 19.5 0.7 1.7 1 0 0 1 1 1 1 Death effector domain DUF1877 PF08974.10 KFM77430.1 - 0.071 13.2 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) SIX1_SD PF16878.5 KFM77431.1 - 9.5e-49 164.6 0.1 1.8e-48 163.7 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFM77431.1 - 9.3e-15 54.2 1.1 2.4e-14 52.9 0.6 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFM77431.1 - 1.2e-12 47.5 1.1 2.3e-12 46.6 1.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFM77431.1 - 0.0081 15.6 0.1 0.022 14.2 0.1 1.7 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 KFM77431.1 - 0.013 15.5 0.0 0.045 13.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix YdaS_antitoxin PF15943.5 KFM77431.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF4371 PF14291.6 KFM77432.1 - 2.3e-05 24.1 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM77432.1 - 0.00028 20.6 0.1 0.00083 19.1 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KFM77432.1 - 0.0079 16.2 0.2 0.022 14.8 0.2 1.8 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_12 PF18658.1 KFM77432.1 - 0.037 13.6 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type MRAP PF15183.6 KFM77433.1 - 0.0064 16.4 0.9 0.0066 16.4 0.9 1.1 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family FAST_1 PF06743.15 KFM77436.1 - 1.3e-11 44.3 6.9 9.5e-11 41.5 0.2 3.8 3 1 1 4 4 4 1 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.12 KFM77436.1 - 0.0026 18.5 0.6 0.0091 16.8 0.1 2.3 2 1 0 2 2 2 1 FAST kinase-like protein, subdomain 2 RAP PF08373.10 KFM77436.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 RAP domain DUF4874 PF16173.5 KFM77436.1 - 0.031 14.0 1.1 0.068 12.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4874) Spore_Cse60 PF10957.8 KFM77436.1 - 0.2 11.7 1.8 2 8.5 0.1 3.3 4 0 0 4 4 4 0 Sporulation protein Cse60 DNA_pol_A_exo1 PF01612.20 KFM77437.1 - 7.1e-46 156.1 0.9 1.1e-45 155.5 0.9 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KFM77437.1 - 6.4e-15 55.6 0.3 1.7e-13 51.0 0.0 2.9 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KFM77437.1 - 3.3e-14 52.6 0.0 6.5e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 HRDC domain NRDE-2 PF08424.10 KFM77439.1 - 4.7e-41 141.0 0.0 5.1e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference HAGH_C PF16123.5 KFM77441.1 - 6.5e-27 93.9 0.0 9.9e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KFM77441.1 - 5.4e-10 39.6 2.8 1.3e-08 35.1 2.7 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFM77441.1 - 0.0064 16.0 0.1 0.013 15.0 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_38N PF01074.22 KFM77442.1 - 1e-86 290.9 7.4 1.5e-86 290.3 7.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFM77442.1 - 4.2e-27 95.6 1.2 6.1e-27 95.1 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFM77442.1 - 2.8e-20 72.2 0.2 7.5e-20 70.9 0.2 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Smg8_Smg9 PF10220.9 KFM77443.1 - 6e-219 729.7 2.3 6.6e-219 729.5 2.3 1.0 1 0 0 1 1 1 1 Smg8_Smg9 FYVE PF01363.21 KFM77444.1 - 0.00018 21.6 0.2 0.00025 21.1 0.2 1.2 1 0 0 1 1 1 1 FYVE zinc finger DUF5606 PF18347.1 KFM77444.1 - 0.16 12.2 0.1 3.4 7.9 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5606) Rap_GAP PF02145.15 KFM77445.1 - 0.0047 16.5 0.0 0.2 11.2 0.0 2.7 2 0 0 2 2 2 2 Rap/ran-GAP CLPTM1 PF05602.12 KFM77446.1 - 6e-147 490.1 2.9 7.4e-147 489.8 2.9 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KFM77446.1 - 0.0047 16.7 5.4 0.29 10.9 0.4 2.9 3 0 0 3 3 3 2 PQ loop repeat COX7a PF02238.15 KFM77447.1 - 0.00024 21.5 0.0 0.00037 20.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII G6PD_N PF00479.22 KFM77447.1 - 0.07 13.8 0.0 0.081 13.5 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain LRR_4 PF12799.7 KFM77449.1 - 6.2e-15 55.1 1.6 1.7e-06 28.2 0.1 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM77449.1 - 1.1e-08 34.8 7.2 0.001 18.8 0.6 2.8 2 1 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 KFM77449.1 - 1.8e-06 27.6 0.1 2e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KFM77449.1 - 0.031 14.3 10.8 1 9.6 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KFM77449.1 - 2 9.3 7.9 32 5.6 0.2 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat APC_rep PF18797.1 KFM77451.1 - 1.8e-25 89.7 0.1 4.6e-25 88.3 0.1 1.8 1 0 0 1 1 1 1 Adenomatous polyposis coli (APC) repeat Arm PF00514.23 KFM77451.1 - 8.3e-08 32.0 1.6 0.0043 17.1 0.1 4.1 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Arm PF00514.23 KFM77452.1 - 1.8e-13 50.0 7.2 1.1e-07 31.7 0.1 4.2 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Arm_APC_u3 PF16629.5 KFM77452.1 - 5.8e-07 29.4 0.1 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Armadillo-associated region on APC APC_r PF05923.12 KFM77452.1 - 4.6e-05 23.0 0.7 0.0001 21.9 0.7 1.6 1 0 0 1 1 1 1 APC repeat B12D PF06522.11 KFM77454.1 - 3.2e-24 84.5 0.1 3.9e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-H2C2_2 PF13465.6 KFM77456.1 - 7e-32 108.4 51.7 6.4e-09 35.8 0.6 9.9 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM77456.1 - 2.9e-21 74.3 50.1 0.008 16.9 0.7 9.2 8 0 0 8 8 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM77456.1 - 1.1e-11 44.5 93.5 0.00018 21.8 1.7 10.0 12 0 0 12 12 8 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM77456.1 - 3.5e-05 24.0 17.1 0.37 11.1 0.2 7.6 7 0 0 7 7 6 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM77456.1 - 0.00066 19.9 1.3 0.00066 19.9 1.3 6.9 4 2 0 5 5 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFM77456.1 - 0.002 18.0 32.0 0.097 12.6 0.7 6.7 6 1 1 7 7 7 4 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 KFM77456.1 - 0.015 15.4 0.9 0.015 15.4 0.9 4.9 4 0 0 4 4 4 0 Zinc ribbon domain zf-MYST PF17772.1 KFM77456.1 - 0.037 13.7 9.1 2.6 7.7 0.0 5.7 4 2 2 6 6 6 0 MYST family zinc finger domain zinc_ribbon_9 PF14369.6 KFM77456.1 - 0.25 11.6 0.1 0.25 11.6 0.1 5.7 7 0 0 7 7 6 0 zinc-ribbon FYVE PF01363.21 KFM77456.1 - 0.5 10.5 25.2 72 3.6 5.7 4.5 1 1 2 3 3 3 0 FYVE zinc finger zf-met PF12874.7 KFM77456.1 - 0.71 10.3 24.8 1.3 9.5 1.8 6.8 7 0 0 7 7 7 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 KFM77456.1 - 2.4 8.3 22.3 15 5.8 0.1 6.7 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3653 PF12375.8 KFM77457.1 - 0.054 13.6 0.3 3.5 7.8 0.1 2.1 1 1 1 2 2 2 0 Phage protein zf_CopZ PF18423.1 KFM77457.1 - 0.089 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Zinc binding domain FERM_N PF09379.10 KFM77458.1 - 2.9e-06 27.1 0.1 3e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 FERM N-terminal domain Ribosomal_L9_N PF01281.19 KFM77459.1 - 2.3e-12 46.3 0.0 4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Zn-C2H2_12 PF18112.1 KFM77460.1 - 1.7e-07 31.5 0.9 5.9e-07 29.8 0.9 2.0 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain APG6_N PF17675.1 KFM77460.1 - 0.014 15.9 18.3 0.14 12.7 2.5 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region MerR-DNA-bind PF09278.11 KFM77460.1 - 0.051 14.1 6.7 0.5 10.9 0.1 2.6 2 0 0 2 2 2 0 MerR, DNA binding SBDS PF01172.18 KFM77460.1 - 0.053 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein FIT1_2 PF17357.2 KFM77460.1 - 0.33 11.1 3.8 3.9 7.6 1.1 2.5 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 Jnk-SapK_ap_N PF09744.9 KFM77460.1 - 0.6 10.3 22.5 0.088 13.0 7.7 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Rad50_zn_hook PF04423.14 KFM77460.1 - 0.69 9.8 0.0 0.69 9.8 0.0 3.7 4 0 0 4 4 4 0 Rad50 zinc hook motif Macoilin PF09726.9 KFM77460.1 - 5.3 5.5 21.1 0.092 11.3 4.5 2.1 2 0 0 2 2 2 0 Macoilin family DHR10 PF18595.1 KFM77460.1 - 5.6 7.0 21.7 4.6 7.3 4.2 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain RL10P_insert PF17777.1 KFM77461.1 - 1.3e-23 82.8 0.0 2.8e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KFM77461.1 - 4.9e-18 65.1 2.5 5.3e-18 65.0 0.0 2.4 3 0 0 3 3 3 1 Ribosomal protein L10 Auxin_repressed PF05564.12 KFM77461.1 - 0.073 13.8 1.2 0.12 13.1 0.1 2.0 2 0 0 2 2 2 0 Dormancy/auxin associated protein Flagellin_C PF00700.21 KFM77461.1 - 0.14 12.6 0.6 0.32 11.4 0.6 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region SDF PF00375.18 KFM77463.1 - 3e-21 75.9 5.5 3.6e-21 75.6 5.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Ubiquitin_4 PF18036.1 KFM77465.1 - 4.5e-29 100.3 2.2 6.1e-29 99.9 1.2 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 KFM77465.1 - 1.4e-06 28.0 2.0 0.02 14.6 0.1 3.0 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 KFM77465.1 - 0.0081 16.0 0.5 0.033 14.0 0.5 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like USP7_C2 PF14533.6 KFM77465.1 - 0.022 14.5 0.1 0.032 14.0 0.1 1.3 1 1 0 1 1 1 0 Ubiquitin-specific protease C-terminal dCache_3 PF14827.6 KFM77465.1 - 0.064 12.9 0.0 0.096 12.3 0.0 1.1 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase PDGLE PF13190.6 KFM77465.1 - 0.14 12.0 0.2 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 PDGLE domain DUF2256 PF10013.9 KFM77465.1 - 0.23 11.6 0.9 0.39 10.9 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) VPS9 PF02204.18 KFM77466.1 - 3.4e-25 88.3 0.2 1.1e-24 86.6 0.2 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFM77466.1 - 2.1e-18 66.4 3.0 8.7e-18 64.4 3.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) zf-A20 PF01754.16 KFM77466.1 - 2.3e-12 46.6 9.6 4.7e-12 45.6 9.6 1.6 1 0 0 1 1 1 1 A20-like zinc finger Mrpl_C PF18502.1 KFM77466.1 - 0.055 13.7 2.1 0.17 12.2 2.1 1.8 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain DUF892 PF05974.12 KFM77466.1 - 0.13 12.3 0.4 0.84 9.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF892) HMG_CoA_synt_C PF08540.10 KFM77467.1 - 0.07 12.7 0.2 0.19 11.3 0.2 1.7 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal Pkinase PF00069.25 KFM77468.1 - 2.4e-46 158.3 0.1 5.8e-46 157.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM77468.1 - 3e-24 85.7 0.0 4.8e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM77468.1 - 0.00045 19.6 0.0 0.00045 19.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM77468.1 - 0.00059 19.8 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFM77468.1 - 0.013 15.1 0.1 0.032 13.8 0.1 1.7 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KFM77468.1 - 0.014 14.4 0.2 0.021 13.8 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 KFM77468.1 - 0.087 12.4 2.8 2.3 7.8 0.2 2.8 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 PulA_N1 PF17999.1 KFM77468.1 - 0.14 12.9 1.2 3.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Pullulanase N1-terminal domain Peptidase_C26 PF07722.13 KFM77469.1 - 8.3e-18 64.9 0.0 4.3e-17 62.6 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KFM77469.1 - 2.2e-08 34.1 0.0 3.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I MMM1 PF10296.9 KFM77470.1 - 4.1e-08 32.6 0.6 8.1e-08 31.7 0.6 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 KFM77470.1 - 0.041 14.4 0.1 0.11 13.0 0.1 1.9 1 1 0 1 1 1 0 PH domain PQQ_2 PF13360.6 KFM77471.1 - 4.5e-08 33.0 0.0 0.00031 20.4 0.0 2.0 1 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KFM77471.1 - 3.7e-05 23.4 0.0 0.0018 18.1 0.0 2.9 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 KFM77471.1 - 0.0019 18.6 0.0 0.21 12.1 0.0 3.5 4 0 0 4 4 4 1 PQQ-like domain Pkinase PF00069.25 KFM77472.1 - 9.9e-39 133.3 0.0 1.3e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM77472.1 - 6.8e-28 97.7 0.0 9.9e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM77472.1 - 1.8e-07 30.3 0.0 1.2e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFM77472.1 - 2.9e-05 24.1 0.0 0.08 12.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Ribonuc_2-5A PF06479.12 KFM77472.1 - 0.0002 21.5 0.0 0.00048 20.3 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease 2-5A Kdo PF06293.14 KFM77472.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 KFM77473.1 - 1.8e-25 89.2 3.6 5.4e-16 58.8 0.6 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM77473.1 - 4.2e-23 79.1 8.8 1.9e-08 33.3 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFM77473.1 - 2.5e-18 64.3 4.6 3.3e-08 32.8 0.1 4.2 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFM77473.1 - 5.9e-17 61.3 8.2 2.8e-15 55.9 0.6 3.5 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFM77473.1 - 2.3e-15 55.3 3.8 8.7e-06 25.0 0.0 3.5 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 KFM77473.1 - 1.7e-05 25.1 0.4 0.0078 16.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFM77473.1 - 0.00012 22.0 1.3 0.00066 19.6 0.2 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFM77473.1 - 0.0005 20.3 0.5 0.0067 16.7 0.1 2.2 2 1 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 KFM77473.1 - 0.0012 19.0 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 2 Dockerin type I domain EF-hand_11 PF08976.11 KFM77473.1 - 0.01 16.7 0.1 0.06 14.2 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain UPF0154 PF03672.13 KFM77473.1 - 0.042 13.9 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Beta-lactamase2 PF13354.6 KFM77473.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family Pyr_redox_dim PF02852.22 KFM77474.1 - 2e-18 66.6 0.1 2.2e-18 66.5 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.14 KFM77476.1 - 2.4e-07 30.3 0.3 2.5e-07 30.2 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFM77476.1 - 3.1e-07 30.1 2.2 3.5e-07 29.9 2.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM77476.1 - 0.00011 21.5 2.1 0.00012 21.3 2.1 1.0 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFM77476.1 - 0.00013 20.8 0.6 0.00014 20.7 0.6 1.0 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KFM77476.1 - 0.00033 20.0 0.0 0.00035 19.9 0.0 1.0 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KFM77476.1 - 0.00051 20.2 1.8 0.00063 19.9 1.8 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFM77476.1 - 0.0011 18.2 1.4 0.0011 18.1 1.4 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KFM77476.1 - 0.0039 16.8 1.4 0.0042 16.7 1.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFM77476.1 - 0.0041 16.4 0.1 0.0044 16.3 0.1 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KFM77476.1 - 0.0092 15.3 1.7 0.011 15.0 1.7 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM77476.1 - 0.016 15.7 0.8 0.02 15.4 0.8 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFM77476.1 - 0.044 12.8 0.8 0.05 12.7 0.8 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein tRNA_m1G_MT PF01746.21 KFM77478.1 - 7.6e-26 91.0 0.0 1.9e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF4313 PF14190.6 KFM77478.1 - 0.04 13.9 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4313) Peptidase_M2 PF01401.18 KFM77479.1 - 4.9e-122 408.4 9.1 6.2e-122 408.1 9.1 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme NYD-SP28 PF14772.6 KFM77479.1 - 0.032 14.3 0.4 2.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Sperm tail IlvC PF01450.19 KFM77479.1 - 0.051 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Transposase_1 PF01359.18 KFM77481.1 - 1.1e-21 76.5 0.2 2.2e-21 75.4 0.2 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_32 PF13565.6 KFM77481.1 - 5.1e-07 30.2 0.9 2.2e-06 28.2 0.0 2.6 3 1 0 3 3 3 1 Homeodomain-like domain DDE_3 PF13358.6 KFM77481.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 KFM77481.1 - 0.068 13.2 0.0 0.27 11.3 0.0 2.1 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KFM77481.1 - 0.07 13.4 0.4 0.27 11.5 0.3 2.0 2 0 0 2 2 2 0 Transposase HTH_28 PF13518.6 KFM77481.1 - 0.1 12.8 0.2 0.38 10.9 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain Myb_DNA-binding PF00249.31 KFM77482.1 - 1.3e-20 73.3 9.6 7.8e-13 48.4 0.1 4.5 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM77482.1 - 9.3e-16 57.8 9.2 3e-09 37.0 0.0 4.1 3 1 1 4 4 4 3 Myb-like DNA-binding domain DDE_1 PF03184.19 KFM77484.1 - 9.6e-21 74.2 0.1 1.2e-20 73.8 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TAF1_subA PF14929.6 KFM77484.1 - 0.033 13.6 0.1 0.045 13.2 0.1 1.2 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A ATP-grasp_2 PF08442.10 KFM77485.1 - 8.9e-79 263.7 1.6 1.4e-78 263.1 1.6 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KFM77485.1 - 7.8e-25 87.5 1.2 1.4e-24 86.7 1.2 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFM77485.1 - 4.5e-09 36.1 0.9 1.9e-08 34.0 0.2 2.0 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KFM77485.1 - 7.9e-05 22.5 0.3 0.00063 19.6 0.0 2.2 1 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Citrate_bind PF16114.5 KFM77485.1 - 0.0071 15.9 0.2 0.013 15.0 0.2 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Succ_CoA_lig PF13607.6 KFM77485.1 - 0.098 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain B-block_TFIIIC PF04182.12 KFM77485.1 - 0.099 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Vitellogenin_N PF01347.22 KFM77486.1 - 4.8e-07 28.6 0.5 0.0088 14.5 0.0 2.4 2 0 0 2 2 2 2 Lipoprotein amino terminal region polyprenyl_synt PF00348.17 KFM77488.1 - 0.018 14.1 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Polyprenyl synthetase polyprenyl_synt PF00348.17 KFM77489.1 - 2.4e-28 98.9 0.1 2.9e-28 98.6 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase TonB_C PF03544.14 KFM77491.1 - 1.9 9.0 7.3 0.62 10.5 0.6 3.0 2 1 1 3 3 3 0 Gram-negative bacterial TonB protein C-terminal HAD PF12710.7 KFM77492.1 - 9.4e-16 58.8 0.1 1.9e-15 57.7 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM77492.1 - 1.3e-15 58.3 0.0 1.8e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFM77492.1 - 4.6e-05 23.0 0.0 6.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 KFM77492.1 - 0.00061 19.3 0.0 0.0024 17.3 0.0 1.7 1 1 0 1 1 1 1 Putative Phosphatase OAR PF03826.17 KFM77494.1 - 3e-09 36.4 0.2 5.5e-09 35.6 0.2 1.5 1 0 0 1 1 1 1 OAR domain TBCA PF02970.16 KFM77496.1 - 2.1e-28 98.5 12.6 2.1e-28 98.5 12.6 1.7 2 0 0 2 2 2 1 Tubulin binding cofactor A DUF4355 PF14265.6 KFM77496.1 - 1.4 9.2 16.7 0.13 12.5 7.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF1674 PF07896.12 KFM77498.1 - 2.6e-19 69.4 6.1 2.6e-19 69.4 6.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Lectin_C PF00059.21 KFM77499.1 - 8.9e-57 190.5 19.7 2.4e-20 73.3 1.0 4.3 4 0 0 4 4 4 4 Lectin C-type domain UL45 PF05473.12 KFM77499.1 - 4e-07 29.9 4.2 0.05 13.2 0.2 3.7 3 1 0 3 3 3 3 UL45 protein, carbohydrate-binding C-type lectin-like BssB_TutG PF18512.1 KFM77502.1 - 0.032 14.1 0.6 0.032 14.1 0.6 1.6 2 0 0 2 2 2 0 Benzylsuccinate synthase beta subunit Peptidase_C2 PF00648.21 KFM77503.1 - 1.3e-42 145.9 0.0 5.7e-42 143.8 0.0 1.8 2 0 0 2 2 2 1 Calpain family cysteine protease MIT PF04212.18 KFM77503.1 - 7.4e-17 61.2 19.6 1.9e-08 34.2 3.8 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Calpain_III PF01067.22 KFM77503.1 - 4.6e-16 59.3 0.0 2.4e-12 47.3 0.1 3.1 2 1 0 2 2 2 2 Calpain large subunit, domain III Sel1 PF08238.12 KFM77503.1 - 0.24 12.1 1.0 1.4 9.7 0.1 2.6 2 0 0 2 2 2 0 Sel1 repeat TPR_11 PF13414.6 KFM77503.1 - 0.48 10.2 6.9 4.9 6.9 0.6 3.5 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.6 KFM77503.1 - 2.7 8.5 4.3 3.5 8.1 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Bromodomain PF00439.25 KFM77504.1 - 3.9e-12 46.1 0.1 1.4e-11 44.3 0.1 2.0 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 KFM77504.1 - 1.2e-07 32.0 0.9 1.2e-07 32.0 0.9 3.6 2 2 0 2 2 2 1 PWWP domain PHD PF00628.29 KFM77504.1 - 3.1e-05 23.8 22.0 0.00025 20.9 8.8 4.1 2 2 1 3 3 3 2 PHD-finger zf-CHY PF05495.12 KFM77504.1 - 0.81 10.2 11.6 3.3 8.3 3.4 3.0 2 0 0 2 2 2 0 CHY zinc finger Trm112p PF03966.16 KFM77504.1 - 1.3 9.7 4.1 24 5.6 2.0 3.3 2 1 0 2 2 2 0 Trm112p-like protein Spore_III_AB PF09548.10 KFM77504.1 - 2.8 8.0 7.8 8.4 6.5 7.8 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) C1_1 PF00130.22 KFM77504.1 - 5.2 7.0 11.3 1.6 8.7 3.4 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HTH_Tnp_Tc3_2 PF01498.18 KFM77506.1 - 5e-16 58.7 2.2 5e-16 58.7 2.2 1.7 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM77506.1 - 3.7e-12 46.2 0.0 6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RGS PF00615.19 KFM77507.1 - 2.2e-10 40.8 0.1 2.9e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF1759 PF03564.15 KFM77508.1 - 1.6e-30 106.0 0.0 5.1e-30 104.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 KFM77508.1 - 1e-11 44.9 0.1 2.2e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 KFM77508.1 - 0.00018 22.1 0.0 0.00044 20.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KFM77508.1 - 0.026 14.3 0.1 0.054 13.3 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KFM77508.1 - 0.051 14.1 0.0 0.29 11.7 0.0 2.3 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4796 PF16044.5 KFM77511.1 - 3e-66 222.6 3.3 3.4e-66 222.4 3.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4796) RhoGEF PF00621.20 KFM77512.1 - 1.5e-45 155.7 0.1 3e-45 154.7 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 KFM77512.1 - 0.029 14.3 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 PH domain PTCB-BRCT PF12738.7 KFM77513.1 - 1.8e-21 75.8 0.9 5.1e-14 52.0 0.1 3.1 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 KFM77513.1 - 9.3e-14 51.6 0.4 1.4e-06 28.6 0.0 2.8 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFM77513.1 - 5.3e-09 36.2 0.5 2.9e-05 24.3 0.1 2.4 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 KFM77513.1 - 3.6e-06 27.3 0.3 0.025 15.0 0.2 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KFM77513.1 - 0.021 14.9 0.0 0.27 11.3 0.0 2.5 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain Phasin PF05597.11 KFM77514.1 - 0.00012 22.1 2.1 0.00018 21.5 2.1 1.3 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 KFM77514.1 - 0.001 19.0 0.8 0.0014 18.6 0.8 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1690 PF07956.11 KFM77514.1 - 0.0087 16.5 2.8 0.013 15.9 2.8 1.2 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) VPS38 PF17649.1 KFM77514.1 - 0.0097 14.8 0.5 0.01 14.7 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 38 EzrA PF06160.12 KFM77514.1 - 0.011 14.0 0.4 0.013 13.7 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA IFT57 PF10498.9 KFM77514.1 - 0.015 14.3 0.8 0.022 13.7 0.8 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 KFM77514.1 - 0.017 15.2 1.7 0.025 14.6 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3135 PF11333.8 KFM77514.1 - 0.03 14.6 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) DUF5446 PF17522.2 KFM77514.1 - 0.033 14.3 2.3 0.062 13.5 2.0 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5446) ApoLp-III PF07464.11 KFM77514.1 - 0.037 14.1 3.5 0.054 13.6 3.5 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4709 PF15821.5 KFM77514.1 - 0.048 13.9 0.9 0.081 13.2 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4709) DUF4404 PF14357.6 KFM77514.1 - 0.056 14.1 0.4 0.1 13.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) HIP1_clath_bdg PF16515.5 KFM77514.1 - 0.088 13.4 2.0 0.13 12.9 2.0 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ApoO PF09769.9 KFM77514.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein O YtxH PF12732.7 KFM77514.1 - 0.37 11.4 2.3 0.77 10.3 2.3 1.7 1 1 0 1 1 1 0 YtxH-like protein SCHIP-1 PF10148.9 KFM77516.1 - 4.8e-68 229.3 11.1 4.8e-68 229.3 11.1 3.3 2 1 0 2 2 2 1 Schwannomin-interacting protein 1 FEZ PF07763.13 KFM77516.1 - 0.018 14.8 0.4 0.018 14.8 0.4 2.2 2 0 0 2 2 2 0 FEZ-like protein DP PF08781.10 KFM77517.1 - 4.7e-51 172.3 1.0 1e-50 171.2 1.0 1.6 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 KFM77517.1 - 2.9e-26 91.3 0.0 6.8e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Cnd1 PF12717.7 KFM77518.1 - 3e-06 27.4 0.9 9.2e-06 25.8 0.9 1.8 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFM77518.1 - 3.9e-05 22.4 3.0 0.00015 20.5 1.0 2.4 1 1 1 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.6 KFM77518.1 - 6.4e-05 23.3 0.2 0.0052 17.1 0.1 2.4 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KFM77518.1 - 0.0018 18.4 0.1 8.1 7.0 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat YhdX PF17444.2 KFM77518.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized YhdX-like DUF4042 PF13251.6 KFM77518.1 - 0.013 15.2 0.7 11 5.7 0.0 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4042) ERAP1_C PF11838.8 KFM77518.1 - 0.044 13.3 0.1 0.077 12.5 0.1 1.5 1 1 0 1 1 1 0 ERAP1-like C-terminal domain Carb_anhydrase PF00194.21 KFM77518.1 - 0.15 11.6 0.1 0.32 10.5 0.1 1.6 1 1 0 1 1 1 0 Eukaryotic-type carbonic anhydrase HEAT PF02985.22 KFM77519.1 - 9.1e-09 34.8 0.0 0.091 13.1 0.0 4.4 3 0 0 3 3 3 3 HEAT repeat Cnd1 PF12717.7 KFM77519.1 - 0.0002 21.5 2.5 0.097 12.7 0.1 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM77519.1 - 0.0036 17.7 0.4 5.6 7.4 0.0 3.6 4 1 1 5 5 5 3 HEAT repeats Self-incomp_S1 PF05938.11 KFM77520.1 - 0.034 14.7 1.5 0.049 14.2 1.5 1.3 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 BRICHOS PF04089.14 KFM77522.1 - 3.4 8.0 6.3 0.79 10.0 1.0 2.1 1 1 1 2 2 2 0 BRICHOS domain MARVEL PF01284.23 KFM77524.1 - 2.1e-23 83.0 4.8 2.9e-23 82.5 4.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 KFM77524.1 - 0.033 14.0 6.9 0.11 12.2 6.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF588) Ribosomal_L31e PF01198.19 KFM77525.1 - 6.3e-49 164.1 0.7 8.4e-49 163.7 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.15 KFM77525.1 - 0.1 12.4 0.1 0.56 10.1 0.0 1.9 1 1 1 2 2 2 0 DNA mismatch endonuclease Vsr Sulfate_transp PF00916.20 KFM77526.1 - 5.2e-114 380.9 18.1 8.1e-114 380.3 18.1 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFM77526.1 - 1.5e-23 82.6 0.2 2.8e-23 81.8 0.2 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KFM77526.1 - 0.0096 16.3 3.1 0.0096 16.3 3.1 3.3 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily DUF4133 PF13571.6 KFM77526.1 - 5.1 7.5 10.3 10 6.6 0.3 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4133) DUF4728 PF15860.5 KFM77527.1 - 0.58 10.9 2.6 0.85 10.3 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4728) Pkinase PF00069.25 KFM77529.1 - 9.9e-54 182.4 0.0 9.9e-54 182.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM77529.1 - 1.2e-30 106.7 0.0 2.2e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM77529.1 - 0.15 12.0 0.1 1.6 8.6 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family CAF1 PF04857.20 KFM77531.1 - 1.9e-23 83.2 1.0 1.7e-11 43.9 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease RNase_H_2 PF13482.6 KFM77531.1 - 0.0004 20.4 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 RNase_H superfamily MFS_1_like PF12832.7 KFM77532.1 - 4.3e-86 289.2 20.5 5.1e-86 288.9 20.5 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM77532.1 - 1.2e-19 70.5 41.6 3.4e-08 32.8 2.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 KFM77532.1 - 1.3e-09 37.3 19.8 4.2e-05 22.5 0.8 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_1_like PF12832.7 KFM77533.1 - 4.1e-97 325.5 10.2 5.1e-97 325.1 10.2 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM77533.1 - 1.6e-20 73.4 40.3 1e-09 37.8 0.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 KFM77533.1 - 1.8e-06 27.0 14.3 3.3e-05 22.8 0.2 2.8 2 1 0 2 2 2 2 LacY proton/sugar symporter MFS_1_like PF12832.7 KFM77534.1 - 1.4e-50 172.3 4.2 1.8e-50 171.9 4.2 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM77534.1 - 4.3e-06 25.9 33.2 0.00077 18.5 17.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily zf-H2C2_2 PF13465.6 KFM77535.1 - 1.4e-29 101.2 20.8 1.8e-08 34.4 0.3 4.1 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM77535.1 - 5.8e-16 58.0 25.6 1.1e-05 25.5 0.6 4.4 4 1 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM77535.1 - 2e-11 43.7 24.2 0.00085 20.0 0.8 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KFM77535.1 - 3e-09 36.9 24.7 0.033 14.6 0.7 4.5 4 1 0 4 4 4 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM77535.1 - 1.6e-08 34.2 9.4 0.013 15.2 0.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc-finger domain DUF2256 PF10013.9 KFM77535.1 - 4.8e-06 26.6 12.7 0.33 11.1 0.3 4.2 4 0 0 4 4 4 3 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_jaz PF12171.8 KFM77535.1 - 8.7e-06 25.9 17.8 0.46 10.8 0.2 4.6 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM77535.1 - 2.2e-05 24.3 28.0 0.017 15.1 0.8 4.6 4 1 0 4 4 4 3 C2H2-type zinc finger zf-trcl PF13451.6 KFM77535.1 - 0.00012 21.9 12.6 0.49 10.3 0.2 4.1 4 0 0 4 4 4 2 Probable zinc-ribbon domain zf-DBF PF07535.12 KFM77535.1 - 0.00012 22.1 8.7 3.9 7.7 0.1 4.2 4 0 0 4 4 4 1 DBF zinc finger zf-Di19 PF05605.12 KFM77535.1 - 0.0031 17.8 17.3 0.021 15.1 1.7 3.6 1 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFM77535.1 - 0.0044 16.9 8.2 12 6.0 0.1 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM77535.1 - 0.0065 16.6 9.7 0.041 14.0 1.3 2.2 1 1 1 2 2 2 2 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 KFM77535.1 - 0.0066 16.3 16.3 0.36 10.7 3.4 3.9 1 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TRAF6_Z2 PF18048.1 KFM77535.1 - 0.0074 16.4 2.2 9.7 6.4 0.0 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_2 PF12756.7 KFM77535.1 - 0.013 15.9 15.6 0.45 10.9 0.4 3.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM77535.1 - 0.019 14.8 9.3 1.4 8.8 0.1 3.3 2 2 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM77535.1 - 0.02 15.0 8.2 4.3 7.5 0.0 4.0 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM77535.1 - 0.022 14.4 14.5 0.066 12.8 0.5 3.9 1 1 3 4 4 4 0 MYST family zinc finger domain Zf_RING PF16744.5 KFM77535.1 - 0.03 14.4 12.9 9.5 6.4 0.1 4.0 1 1 2 3 3 3 0 KIAA1045 RING finger ADK_lid PF05191.14 KFM77535.1 - 0.035 14.1 6.7 1.4 8.9 0.2 3.3 2 2 2 4 4 4 0 Adenylate kinase, active site lid zf-HIT PF04438.16 KFM77535.1 - 0.039 13.8 11.8 4.3 7.3 0.1 4.1 4 0 0 4 4 4 0 HIT zinc finger DUF2039 PF10217.9 KFM77535.1 - 0.041 14.2 14.4 0.12 12.7 2.4 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2039) zf_UBZ PF18439.1 KFM77535.1 - 0.057 13.0 13.2 4.8 6.9 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Baculo_IE-1 PF05290.11 KFM77535.1 - 0.074 13.0 10.6 3.1 7.7 0.1 3.8 1 1 3 4 4 4 0 Baculovirus immediate-early protein (IE-0) A2L_zn_ribbon PF08792.10 KFM77535.1 - 0.14 11.9 13.4 5 7.0 0.2 4.2 4 0 0 4 4 4 0 A2L zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM77535.1 - 0.25 12.1 8.1 3.6 8.4 0.7 2.2 1 1 0 2 2 2 0 zinc-ribbon family C1_4 PF07975.12 KFM77535.1 - 0.87 9.9 14.1 1.5 9.1 2.4 3.3 1 1 3 4 4 4 0 TFIIH C1-like domain HNH PF01844.23 KFM77535.1 - 1.1 9.5 12.1 10 6.4 0.1 4.0 4 0 0 4 4 4 0 HNH endonuclease Zn-ribbon_8 PF09723.10 KFM77535.1 - 1.2 9.3 10.9 7.8 6.7 1.5 3.0 2 2 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.21 KFM77535.1 - 1.7 8.8 14.4 6.4 7.0 8.3 3.1 1 1 0 2 2 2 0 FYVE zinc finger zf-AN1 PF01428.16 KFM77535.1 - 2.4 8.4 13.1 11 6.3 0.1 4.1 4 0 0 4 4 4 0 AN1-like Zinc finger zf-Dof PF02701.15 KFM77535.1 - 4.8 7.4 11.4 2.8 8.2 0.1 3.8 3 1 1 4 4 4 0 Dof domain, zinc finger FYDLN_acid PF09538.10 KFM77535.1 - 9.2 7.0 6.4 41 4.9 0.1 3.1 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) zf-Paramyx-P PF13008.7 KFM77535.1 - 9.8 5.7 11.6 17 5.0 0.1 3.7 4 0 0 4 4 4 0 Zinc-binding domain of Paramyxoviridae V protein WW PF00397.26 KFM77537.1 - 5e-11 42.5 5.5 1.5e-09 37.8 0.2 2.6 2 0 0 2 2 2 2 WW domain PDZ PF00595.24 KFM77537.1 - 8e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM77537.1 - 3.6e-07 29.9 0.0 5.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM77537.1 - 1.1e-05 25.7 0.0 1.6e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 PDZ domain FERM_M PF00373.18 KFM77538.1 - 3.9e-16 59.5 0.5 1.3e-15 57.9 0.5 1.9 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFM77538.1 - 1.9e-05 24.5 0.2 0.00012 22.0 0.1 2.3 2 0 0 2 2 2 1 FERM N-terminal domain FERM_f0 PF16511.5 KFM77538.1 - 0.0024 18.1 0.1 0.0062 16.8 0.1 1.7 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM FERM_F2 PF18377.1 KFM77538.1 - 0.0099 15.8 0.5 0.038 13.9 0.5 2.1 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain TBCC_N PF16752.5 KFM77538.1 - 7 7.1 10.1 23 5.4 0.3 5.3 4 2 1 5 5 5 0 Tubulin-specific chaperone C N-terminal domain zf-AN1 PF01428.16 KFM77539.1 - 1.7e-22 79.3 26.6 1.4e-11 44.4 5.2 3.0 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KFM77539.1 - 0.00047 20.5 20.1 0.011 16.0 6.8 2.6 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain RAP80_UIM PF18282.1 KFM77539.1 - 0.00048 19.8 3.1 0.0011 18.7 3.1 1.5 1 0 0 1 1 1 1 RAP80 N-terminal ubiquitin interaction motif C5HCH PF17982.1 KFM77539.1 - 0.62 10.3 16.9 0.55 10.4 1.8 3.4 2 1 1 3 3 3 0 NSD Cys-His rich domain BACK PF07707.15 KFM77540.1 - 2.4e-05 24.4 0.1 3.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFM77540.1 - 0.0093 16.2 0.1 0.027 14.7 0.1 1.8 1 1 1 2 2 2 1 BTB/POZ domain FMN_dh PF01070.18 KFM77541.1 - 1.5e-59 201.8 0.0 2.3e-58 197.9 0.0 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KFM77541.1 - 0.014 14.7 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 KFM77541.1 - 0.025 14.0 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator PA PF02225.22 KFM77541.1 - 0.033 14.2 0.8 3.9 7.6 0.0 2.3 1 1 0 2 2 2 0 PA domain zf-RING_UBOX PF13445.6 KFM77542.1 - 1.2e-07 31.6 4.6 1.2e-07 31.6 4.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFM77542.1 - 1.4e-07 31.3 4.5 4.6e-07 29.6 4.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM77542.1 - 2.8e-07 30.3 3.5 2.8e-07 30.3 3.5 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFM77542.1 - 1.4e-05 25.1 7.5 1.4e-05 25.1 7.5 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFM77542.1 - 0.00072 19.3 1.0 0.0018 18.1 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KFM77542.1 - 0.0012 19.1 2.8 0.0041 17.4 2.8 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM77542.1 - 0.002 18.0 4.2 0.002 18.0 4.2 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM77542.1 - 0.0077 16.1 4.7 0.0077 16.1 4.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 KFM77542.1 - 0.024 14.7 0.2 0.12 12.5 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM77542.1 - 0.026 14.3 0.1 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_6 PF14835.6 KFM77542.1 - 0.029 14.2 1.9 0.072 13.0 1.9 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KFM77542.1 - 0.032 14.5 0.6 0.11 12.8 0.6 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFM77542.1 - 0.048 13.4 1.1 0.14 11.9 1.1 1.9 1 0 0 1 1 1 0 RING-like zinc finger TPR_8 PF13181.6 KFM77542.1 - 0.062 13.5 0.2 0.23 11.8 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4453 PF14627.6 KFM77542.1 - 0.097 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Rtf2 PF04641.12 KFM77542.1 - 0.11 11.8 6.5 0.058 12.8 4.5 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_10 PF16685.5 KFM77542.1 - 2.3 8.4 11.9 0.076 13.2 4.1 2.5 3 0 0 3 3 3 0 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 KFM77543.1 - 5.1e-10 39.0 15.0 1.5e-09 37.5 15.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM77543.1 - 5.4e-08 32.6 13.3 1.7e-07 31.0 13.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM77543.1 - 5.8e-08 32.5 8.9 1.2e-07 31.4 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFM77543.1 - 5.5e-06 26.4 14.1 1.5e-05 25.0 14.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFM77543.1 - 6.1e-06 26.5 15.1 6.1e-06 26.5 15.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFM77543.1 - 1.5e-05 24.9 13.7 0.00022 21.1 14.5 2.4 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM77543.1 - 5.3e-05 23.0 14.6 0.002 18.0 14.9 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFM77543.1 - 6.1e-05 23.0 15.4 6.1e-05 23.0 15.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 KFM77543.1 - 7.8e-05 22.7 5.5 0.0002 21.4 5.5 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KFM77543.1 - 0.00012 22.2 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_4 PF14570.6 KFM77543.1 - 0.00025 20.8 7.4 0.0011 18.7 5.4 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain LON_substr_bdg PF02190.16 KFM77543.1 - 0.00028 20.8 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-RING_6 PF14835.6 KFM77543.1 - 0.0016 18.3 5.0 0.0039 17.0 5.0 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 KFM77543.1 - 0.015 15.1 6.8 0.015 15.1 6.8 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KFM77543.1 - 0.052 13.8 15.7 0.64 10.4 15.7 2.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 KFM77543.1 - 0.07 13.1 5.7 0.15 12.0 5.2 1.9 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) LON_substr_bdg PF02190.16 KFM77544.1 - 9e-10 38.8 0.0 1e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain SNF PF00209.18 KFM77545.1 - 5.3e-206 685.4 34.9 9e-206 684.6 34.9 1.3 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family MWFE PF15879.5 KFM77545.1 - 1 9.6 3.2 1.8 8.8 0.9 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Pep_M12B_propep PF01562.19 KFM77546.1 - 5.2e-05 23.5 0.0 6.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KFM77547.1 - 0.091 12.7 0.7 0.15 11.9 0.7 1.4 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease DDE_Tnp_1_7 PF13843.6 KFM77548.1 - 8.6e-12 45.0 0.1 9.7e-12 44.8 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Nop25 PF09805.9 KFM77549.1 - 0.66 10.4 7.5 9.5 6.7 2.7 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) SPATA3 PF15662.5 KFM77549.1 - 8.2 7.0 18.4 1.5 9.4 7.2 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family SET PF00856.28 KFM77550.1 - 6.5e-25 88.5 1.1 7.4e-24 85.0 1.1 2.0 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KFM77550.1 - 2.1e-05 25.1 3.0 0.00013 22.5 0.5 2.5 2 0 0 2 2 2 1 Pre-SET motif AWS PF17907.1 KFM77550.1 - 0.018 15.1 2.6 0.018 15.1 2.6 2.1 2 0 0 2 2 2 0 AWS domain Clr5 PF14420.6 KFM77550.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Clr5 domain MULE PF10551.9 KFM77551.1 - 1.9e-07 31.4 0.0 6e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain DUF3652 PF12372.8 KFM77552.1 - 6.9e-11 41.9 0.4 1.9e-10 40.4 0.4 1.9 1 0 0 1 1 1 1 Huntingtin protein region HEAT PF02985.22 KFM77552.1 - 0.011 15.9 0.0 0.08 13.2 0.0 2.6 1 0 0 1 1 1 0 HEAT repeat WD40 PF00400.32 KFM77554.1 - 8.4e-18 64.4 16.5 4e-05 24.3 0.1 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFM77554.1 - 2.1e-07 30.3 4.0 0.08 11.9 0.1 3.9 3 1 1 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KFM77554.1 - 2.3e-07 31.0 6.7 0.005 17.1 0.2 3.8 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain NDUF_C2 PF06374.11 KFM77555.1 - 5.7e-25 87.6 0.2 6.6e-25 87.4 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) DHquinase_II PF01220.19 KFM77557.1 - 0.047 13.3 0.1 0.07 12.8 0.1 1.4 1 1 0 1 1 1 0 Dehydroquinase class II EHN PF06441.12 KFM77557.1 - 0.17 12.2 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 Epoxide hydrolase N terminus GP40 PF11025.8 KFM77558.1 - 0.031 14.0 0.0 0.034 13.9 0.0 1.0 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium UBX PF00789.20 KFM77559.1 - 6.9e-15 55.0 0.0 2e-14 53.5 0.0 1.8 1 1 0 1 1 1 1 UBX domain ubiquitin PF00240.23 KFM77559.1 - 0.00053 19.7 0.1 0.0069 16.1 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin family LppA PF16708.5 KFM77559.1 - 0.12 12.3 0.9 0.22 11.4 0.9 1.5 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium DUF1682 PF07946.14 KFM77559.1 - 6.3 5.9 12.3 9.5 5.3 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Asp-B-Hydro_N PF05279.11 KFM77559.1 - 6.6 6.7 15.8 1.5 8.8 12.0 1.7 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region AAA_23 PF13476.6 KFM77559.1 - 8.8 6.8 11.7 17 5.9 9.3 2.1 2 0 0 2 2 2 0 AAA domain DUF1232 PF06803.12 KFM77560.1 - 7.6e-11 41.6 8.6 1.7e-10 40.5 8.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) zf-RING_UBOX PF13445.6 KFM77560.1 - 2e-10 40.5 3.3 2e-10 40.5 3.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM77560.1 - 6.8e-10 39.0 6.7 1.4e-09 37.9 6.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFM77560.1 - 3.5e-09 36.4 6.9 8.1e-09 35.2 6.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM77560.1 - 3.5e-09 36.4 5.4 5.8e-09 35.7 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM77560.1 - 1.2e-08 34.7 5.7 2.1e-08 33.9 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM77560.1 - 9.1e-08 32.3 8.0 1.5e-07 31.6 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM77560.1 - 3.6e-06 26.8 6.4 3.6e-06 26.8 6.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM77560.1 - 0.00019 21.2 6.4 0.0015 18.3 6.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KFM77560.1 - 0.0002 21.1 1.2 0.00034 20.4 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KFM77560.1 - 0.03 14.1 7.3 0.061 13.1 7.3 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.6 KFM77560.1 - 0.075 12.9 4.5 0.16 11.9 4.3 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF4451 PF14616.6 KFM77560.1 - 0.076 13.2 1.4 8.8 6.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-WRNIP1_ubi PF18279.1 KFM77560.1 - 0.092 13.4 4.2 7.6 7.4 0.5 2.7 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-ANAPC11 PF12861.7 KFM77560.1 - 0.15 12.1 4.7 0.33 11.0 4.7 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.12 KFM77560.1 - 0.16 12.0 4.4 0.28 11.2 4.4 1.4 1 1 0 1 1 1 0 zinc-ribbons Baculo_IE-1 PF05290.11 KFM77560.1 - 0.17 11.8 2.9 0.39 10.7 2.9 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 KFM77560.1 - 2.5 8.0 8.8 15 5.5 9.0 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFM77560.1 - 2.6 8.4 9.4 7.2 7.0 9.4 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFM77560.1 - 3.5 7.8 9.1 13 6.0 9.1 1.9 1 1 0 1 1 1 0 zinc RING finger of MSL2 Prim_Zn_Ribbon PF08273.12 KFM77560.1 - 3.6 7.9 6.6 2.4 8.5 1.8 2.4 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase PTR2 PF00854.21 KFM77561.1 - 1.8e-47 162.1 6.7 1.8e-47 162.1 6.7 1.5 2 0 0 2 2 2 1 POT family MFS_1 PF07690.16 KFM77561.1 - 0.1 11.5 20.4 0.065 12.2 17.8 1.8 1 1 0 1 1 1 0 Major Facilitator Superfamily EGF_MSP1_1 PF12946.7 KFM77562.1 - 0.026 14.6 28.8 0.19 11.8 0.4 4.7 4 0 0 4 4 4 0 MSP1 EGF domain 1 DUF5104 PF17117.5 KFM77562.1 - 0.1 13.1 2.8 5.9 7.4 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5104) Na_sulph_symp PF00939.19 KFM77563.1 - 1.5e-98 330.9 20.5 1.7e-98 330.7 20.5 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFM77563.1 - 6.2e-41 140.6 28.2 8.9e-22 77.6 7.6 3.0 2 1 1 3 3 3 3 Citrate transporter DUF3007 PF11460.8 KFM77563.1 - 0.016 15.4 0.2 0.24 11.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Ni_hydr_CYTB PF01292.20 KFM77563.1 - 6.8 6.2 11.5 0.97 9.0 4.1 2.8 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 Ribosomal_S17 PF00366.20 KFM77564.1 - 5.7e-07 29.6 0.1 7.6e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PH_TFIIH PF08567.11 KFM77565.1 - 2.2e-26 92.0 0.1 5.1e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 KFM77565.1 - 3.6e-22 78.1 1.7 1.4e-17 63.5 0.1 2.9 2 0 0 2 2 2 2 BSD domain JHD PF17811.1 KFM77566.1 - 1.1e-36 125.5 0.3 2.2e-36 124.5 0.3 1.6 1 0 0 1 1 1 1 Jumonji helical domain PHD PF00628.29 KFM77566.1 - 8.5e-10 38.4 11.4 2.4e-09 36.9 11.4 1.8 1 0 0 1 1 1 1 PHD-finger JmjC PF02373.22 KFM77566.1 - 6.6e-08 33.0 0.4 1.2e-06 28.9 0.4 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KFM77566.1 - 1.5e-06 28.1 0.3 1.2e-05 25.2 0.3 2.2 1 1 0 1 1 1 1 Cupin-like domain Isy1 PF06246.12 KFM77567.1 - 1.2e-16 61.1 1.2 1.3e-16 60.9 1.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Xylo_C PF12529.8 KFM77567.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Xylosyltransferase C terminal DUF4837 PF16125.5 KFM77567.1 - 0.077 12.0 0.2 0.09 11.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) Bestrophin PF01062.21 KFM77568.1 - 1.5e-12 47.5 0.5 1.5e-12 47.5 0.5 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel P5-ATPase PF12409.8 KFM77568.1 - 0.13 12.4 1.7 0.2 11.8 1.3 1.6 1 1 1 2 2 2 0 P5-type ATPase cation transporter Bestrophin PF01062.21 KFM77569.1 - 7.5e-33 114.2 0.4 8.1e-33 114.1 0.4 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ig_3 PF13927.6 KFM77570.1 - 2.9e-11 43.8 0.0 4.8e-11 43.1 0.0 1.4 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM77570.1 - 7.5e-09 35.5 0.0 9.7e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM77570.1 - 2.7e-06 27.6 0.0 4.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM77570.1 - 5.3e-05 23.3 0.4 0.00032 20.8 0.1 2.1 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM77570.1 - 0.0012 19.0 0.0 1 9.6 0.0 2.2 1 1 1 2 2 2 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFM77570.1 - 0.053 13.6 0.1 0.097 12.7 0.1 1.5 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFM77570.1 - 0.14 12.5 0.0 0.3 11.5 0.0 1.5 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LRR_6 PF13516.6 KFM77571.1 - 4.8e-14 51.1 4.4 0.0043 17.0 0.0 5.7 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 KFM77571.1 - 1.2e-09 38.3 1.4 0.00022 21.5 0.1 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM77571.1 - 1.2e-05 25.2 4.4 3.7 8.5 0.1 5.6 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.6 KFM77571.1 - 0.00013 21.7 0.4 0.034 13.9 0.0 3.2 2 1 1 3 3 3 2 Leucine rich repeat MIT_LIKE_ACTX PF17556.2 KFM77571.1 - 0.054 14.1 0.2 6.5 7.4 0.1 2.5 2 1 0 2 2 2 0 MIT-like atracotoxin family Ras PF00071.22 KFM77572.1 - 7.6e-61 204.4 1.4 9e-61 204.2 1.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM77572.1 - 6.6e-36 123.2 1.8 7.6e-36 123.0 0.3 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM77572.1 - 1.2e-17 63.9 0.8 1.5e-17 63.6 0.8 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM77572.1 - 4e-07 29.8 1.6 1.4e-06 28.0 0.6 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM77572.1 - 3.4e-06 27.1 0.2 6.3e-06 26.3 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM77572.1 - 3.6e-05 23.2 1.0 7.6e-05 22.2 0.4 1.7 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KFM77572.1 - 0.0001 21.8 0.8 0.00041 19.9 0.8 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM77572.1 - 0.00012 22.0 2.8 0.029 14.3 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFM77572.1 - 0.0039 17.6 0.0 0.0057 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM77572.1 - 0.0062 16.8 0.1 0.018 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFM77572.1 - 0.011 15.5 2.1 0.031 14.0 0.4 2.2 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 KFM77572.1 - 0.017 14.6 0.7 0.034 13.6 0.7 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KFM77572.1 - 0.029 14.9 0.8 0.056 14.0 0.8 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KFM77572.1 - 0.029 14.1 2.3 0.042 13.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 KFM77572.1 - 0.031 13.4 0.0 0.058 12.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AEP1 PF17049.5 KFM77572.1 - 0.034 13.2 1.1 0.043 12.9 1.1 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 AAA_5 PF07728.14 KFM77572.1 - 0.035 14.1 0.2 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KFM77572.1 - 0.038 13.4 0.3 0.13 11.7 0.0 1.9 2 1 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 KFM77572.1 - 0.039 13.7 0.8 2.6 7.8 0.8 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3873 PF12989.7 KFM77572.1 - 0.065 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) AAA_25 PF13481.6 KFM77572.1 - 0.093 12.3 0.0 0.8 9.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 KFM77572.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 KFM77572.1 - 0.11 12.7 0.0 0.4 10.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KFM77572.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 KFM77572.1 - 0.45 11.0 5.9 0.95 9.9 5.9 1.4 1 1 0 1 1 1 0 AAA domain Abhydrolase_1 PF00561.20 KFM77573.1 - 2e-23 83.3 0.1 2.4e-17 63.4 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM77573.1 - 4.6e-19 69.9 0.0 5.4e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM77573.1 - 5.7e-10 38.9 0.1 8.9e-10 38.2 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFM77573.1 - 3.6e-09 36.7 0.3 4.6e-07 29.8 0.3 2.1 1 1 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 KFM77573.1 - 0.0064 15.4 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 KFM77573.1 - 0.01 16.0 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 KFM77573.1 - 0.015 14.9 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Chlorophyllase PF07224.11 KFM77573.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ser_hydrolase PF06821.13 KFM77573.1 - 0.03 14.2 0.0 0.069 13.0 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Palm_thioest PF02089.15 KFM77573.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Palmitoyl protein thioesterase CholecysA-Rec_N PF09193.10 KFM77573.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal PAF-AH_p_II PF03403.13 KFM77573.1 - 0.14 10.7 0.4 0.39 9.2 0.2 1.7 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Patched PF02460.18 KFM77574.1 - 4.2e-78 263.3 23.0 2e-48 165.1 2.8 2.2 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 KFM77574.1 - 1.2e-54 185.4 3.1 1.2e-54 185.4 3.1 1.7 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 KFM77574.1 - 1.7e-52 177.3 10.7 1.7e-52 177.3 10.7 3.6 4 0 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KFM77574.1 - 0.0019 17.2 3.1 0.0019 17.2 3.1 2.5 3 1 0 3 3 3 1 MMPL family MBOAT PF03062.19 KFM77575.1 - 1.4e-31 110.1 16.6 2.1e-31 109.6 16.6 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CDP-OH_P_transf PF01066.21 KFM77576.1 - 0.0055 17.4 2.1 0.053 14.3 1.3 2.2 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TssN PF17555.2 KFM77576.1 - 0.028 13.8 0.6 0.034 13.5 0.6 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF5373 PF17343.2 KFM77576.1 - 0.2 11.4 3.7 0.23 11.3 3.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5373) DUF4131 PF13567.6 KFM77576.1 - 1.2 8.8 3.3 1.5 8.5 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Somatomedin_B PF01033.17 KFM77577.1 - 0.043 14.2 11.5 0.043 14.2 11.5 3.4 3 0 0 3 3 3 0 Somatomedin B domain Metallophos PF00149.28 KFM77578.1 - 6.8e-23 82.2 1.4 6.8e-23 82.2 1.4 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SapB_1 PF05184.15 KFM77578.1 - 3.3e-05 23.8 0.1 7.3e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Saposin-like type B, region 1 Zap1_zf2 PF18217.1 KFM77578.1 - 0.21 11.6 1.9 0.6 10.2 0.6 2.4 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf-C2H2_2 PF12756.7 KFM77578.1 - 1.6 9.1 3.7 4.7 7.6 0.1 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Ets PF00178.22 KFM77580.1 - 2.6e-28 98.3 0.7 4.6e-28 97.5 0.7 1.4 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFM77580.1 - 6.6e-25 86.9 0.1 2.2e-24 85.2 0.0 1.8 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain FbpA PF05833.11 KFM77580.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF5641 PF18701.1 KFM77581.1 - 2.5e-06 27.6 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) RRM_1 PF00076.22 KFM77582.1 - 1.3e-14 53.8 0.0 8.1e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FliH PF02108.16 KFM77582.1 - 0.028 14.5 0.1 0.046 13.8 0.1 1.3 1 0 0 1 1 1 0 Flagellar assembly protein FliH RRM_occluded PF16842.5 KFM77582.1 - 0.1 12.5 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF1182 PF06681.13 KFM77582.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) Thymidylat_synt PF00303.19 KFM77583.1 - 1.7e-117 391.3 0.0 2e-117 391.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase SRP40_C PF05022.12 KFM77584.1 - 1.1e-10 42.2 1.6 1.1e-10 42.2 1.6 4.4 3 0 0 3 3 3 1 SRP40, C-terminal domain Steroid_dh PF02544.16 KFM77585.1 - 1.1e-25 90.4 5.7 1.3e-25 90.2 5.7 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KFM77585.1 - 4.1e-05 23.9 3.8 4.1e-05 23.9 3.8 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KFM77585.1 - 0.0039 16.7 2.6 0.0052 16.3 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2427 PF10348.9 KFM77585.1 - 0.063 13.1 0.5 0.53 10.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) XhlA PF10779.9 KFM77585.1 - 1.5 9.1 3.9 2.6 8.3 3.9 1.4 1 0 0 1 1 1 0 Haemolysin XhlA PI3_PI4_kinase PF00454.27 KFM77587.1 - 2.6e-56 191.2 1.1 1.5e-55 188.7 1.1 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PX PF00787.24 KFM77587.1 - 7e-17 61.4 0.0 1.3e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 PX domain PI3Ka PF00613.20 KFM77587.1 - 1.8e-16 60.1 0.0 2.7e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) C2 PF00168.30 KFM77587.1 - 2.1e-05 24.7 0.4 5.1e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 C2 domain DUF4135 PF13575.6 KFM77587.1 - 0.0013 18.2 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PI3K_C2 PF00792.24 KFM77588.1 - 5.9e-09 36.0 0.0 6.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3Ka PF00613.20 KFM77588.1 - 3.4e-06 26.6 0.1 4.6e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_rbd PF00794.18 KFM77589.1 - 9.9e-07 28.9 0.1 1.9e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF2600 PF10776.9 KFM77589.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) T6SS_VipA PF05591.12 KFM77589.1 - 0.068 13.0 0.1 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 Zap1_zf2 PF18217.1 KFM77589.1 - 0.1 12.6 1.3 9.6 6.3 0.3 2.6 2 0 0 2 2 2 0 Zap1 zinc finger 2 DUF2935 PF11155.8 KFM77590.1 - 0.094 13.1 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DJ-1_PfpI PF01965.24 KFM77592.1 - 2e-05 24.5 0.0 0.0002 21.2 0.0 2.0 2 0 0 2 2 2 1 DJ-1/PfpI family EF-hand_1 PF00036.32 KFM77593.1 - 1.5e-16 58.6 17.8 0.0017 17.8 0.2 5.9 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 KFM77593.1 - 1.6e-15 55.7 10.9 0.0043 16.9 0.1 5.6 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 KFM77593.1 - 1.9e-14 53.9 20.4 1e-07 32.3 0.9 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFM77593.1 - 1.4e-10 40.2 21.6 0.00046 19.5 0.7 5.3 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KFM77593.1 - 0.0011 18.8 9.1 0.94 9.4 0.2 4.5 4 0 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM77593.1 - 0.0013 19.0 23.8 0.084 13.2 9.2 3.3 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Importin_rep PF18773.1 KFM77593.1 - 0.017 14.8 1.0 0.073 12.8 0.2 2.4 2 0 0 2 2 2 0 Importin 13 repeat Nfu_N PF08712.11 KFM77593.1 - 0.078 13.0 0.2 5.8 7.0 0.1 2.5 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal DUF327 PF03885.13 KFM77593.1 - 0.31 11.0 9.5 0.32 11.0 1.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF327) tRNA_lig_kinase PF08303.11 KFM77593.1 - 2 8.5 9.4 3.1 7.8 0.2 3.1 2 1 1 3 3 3 0 tRNA ligase kinase domain FSAP_sig_propep PF03032.15 KFM77593.1 - 5.6 7.1 6.4 13 5.9 0.8 3.4 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide Ank_4 PF13637.6 KFM77594.1 - 3.5e-15 56.1 0.2 6.2e-12 45.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM77594.1 - 4.7e-13 49.5 0.0 6.7e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM77594.1 - 8.4e-13 48.1 0.3 2.6e-06 27.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFM77594.1 - 4.8e-09 35.7 0.1 3.5e-05 23.9 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KFM77594.1 - 5e-09 36.2 0.0 3.9e-06 27.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HasA PF06438.12 KFM77594.1 - 0.041 13.5 0.4 2.1 7.9 0.1 2.1 1 1 1 2 2 2 0 Heme-binding protein A (HasA) EGF PF00008.27 KFM77596.1 - 1.7e-27 95.3 61.1 5e-08 33.1 6.6 5.4 5 1 0 5 5 5 5 EGF-like domain hEGF PF12661.7 KFM77596.1 - 2.7e-17 62.7 68.1 8.4e-08 32.6 2.9 6.6 7 0 0 7 7 7 4 Human growth factor-like EGF EGF_CA PF07645.15 KFM77596.1 - 5.4e-11 42.5 65.6 0.00018 21.6 12.2 5.0 2 2 3 5 5 5 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFM77596.1 - 6.3e-06 26.4 52.1 0.17 12.2 9.3 5.2 2 1 3 5 5 5 4 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 KFM77596.1 - 4.5e-05 23.7 64.3 0.01 16.2 8.1 4.9 5 0 0 5 5 5 4 EGF-like domain cEGF PF12662.7 KFM77596.1 - 0.0019 18.1 1.1 0.0019 18.1 1.1 6.6 5 2 0 5 5 5 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFM77596.1 - 0.01 16.0 5.6 0.01 16.0 5.6 6.0 4 2 1 5 5 5 0 EGF domain Laminin_EGF PF00053.24 KFM77596.1 - 0.014 15.6 55.5 1.7 8.8 7.8 4.3 2 1 2 4 4 4 0 Laminin EGF domain Pacifastin_I PF05375.13 KFM77598.1 - 1.7e-06 27.6 6.2 7.8e-06 25.5 6.2 2.3 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) VWC PF00093.18 KFM77598.1 - 9.4e-05 22.7 13.0 9.4e-05 22.7 13.0 2.4 1 1 1 2 2 2 1 von Willebrand factor type C domain DUF2371 PF10177.9 KFM77599.1 - 0.12 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) VPDSG-CTERM PF18205.1 KFM77599.1 - 0.21 11.4 0.4 5.1 7.0 0.1 2.3 2 0 0 2 2 2 0 VPDSG-CTERM motif AMPK1_CBM PF16561.5 KFM77600.1 - 4.4e-31 106.9 0.2 6.5e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KFM77600.1 - 1.8e-25 89.0 1.7 3e-25 88.3 1.7 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain DUF903 PF06004.12 KFM77600.1 - 0.17 11.8 0.1 0.65 9.9 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) RNA_pol_Rpc34 PF05158.12 KFM77601.1 - 5.1e-27 95.1 1.4 5.5e-27 95.0 1.4 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR_2 PF12802.7 KFM77601.1 - 3.1e-05 23.7 0.0 7.1e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 MarR family MarR PF01047.22 KFM77601.1 - 6.6e-05 22.8 0.2 0.00045 20.1 0.1 2.3 2 0 0 2 2 2 1 MarR family B-block_TFIIIC PF04182.12 KFM77601.1 - 0.00028 21.0 0.4 0.00065 19.8 0.1 1.7 2 1 0 2 2 2 1 B-block binding subunit of TFIIIC TrmB PF01978.19 KFM77601.1 - 0.00087 19.1 0.0 0.0089 15.9 0.0 2.3 1 1 2 3 3 3 1 Sugar-specific transcriptional regulator TrmB z-alpha PF02295.17 KFM77601.1 - 0.0068 16.4 0.4 0.061 13.4 0.1 2.1 2 0 0 2 2 2 1 Adenosine deaminase z-alpha domain HTH_24 PF13412.6 KFM77601.1 - 0.01 15.4 0.2 0.03 13.9 0.2 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 KFM77601.1 - 0.023 15.0 0.1 0.056 13.8 0.0 1.6 1 1 0 1 1 1 0 Transcriptional regulator RPA_C PF08784.11 KFM77601.1 - 0.03 15.0 0.1 0.08 13.6 0.0 1.6 1 1 0 1 1 1 0 Replication protein A C terminal TFIIE_alpha PF02002.17 KFM77601.1 - 0.033 14.1 0.1 0.06 13.2 0.0 1.5 1 1 0 1 1 1 0 TFIIE alpha subunit TBPIP PF07106.13 KFM77601.1 - 0.079 12.9 4.3 15 5.6 0.9 3.5 2 1 0 2 2 2 0 TBPIP/Hop2 winged helix domain HTH_27 PF13463.6 KFM77601.1 - 0.099 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain RNA_pol_Rpc34 PF05158.12 KFM77602.1 - 4.4e-86 289.3 1.9 7e-86 288.6 1.9 1.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.19 KFM77602.1 - 0.00011 22.0 1.1 0.00096 19.0 0.3 2.7 2 1 2 4 4 4 1 Sugar-specific transcriptional regulator TrmB TFA2_Winged_2 PF18121.1 KFM77602.1 - 0.00096 18.8 2.3 0.086 12.5 0.1 3.3 2 1 1 3 3 3 1 TFA2 Winged helix domain 2 B-block_TFIIIC PF04182.12 KFM77602.1 - 0.0013 18.8 0.4 0.0035 17.5 0.4 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC RPA_C PF08784.11 KFM77602.1 - 0.006 17.2 0.5 2.7 8.7 0.0 3.2 2 2 1 3 3 3 1 Replication protein A C terminal HTH_24 PF13412.6 KFM77602.1 - 0.0074 15.8 1.9 0.4 10.3 0.3 2.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 KFM77602.1 - 0.056 13.8 0.1 0.23 11.8 0.1 2.0 2 0 0 2 2 2 0 Transcriptional regulator DsrD PF08679.11 KFM77602.1 - 0.095 13.0 4.2 0.13 12.6 0.0 3.0 3 1 1 4 4 4 0 Dissimilatory sulfite reductase D (DsrD) pP_pnuc_1 PF18165.1 KFM77602.1 - 0.12 12.3 0.3 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease HTH_27 PF13463.6 KFM77602.1 - 0.13 12.8 0.0 1.2 9.7 0.0 2.6 2 1 1 3 3 3 0 Winged helix DNA-binding domain PadR PF03551.14 KFM77602.1 - 0.13 12.2 0.2 0.78 9.8 0.0 2.4 3 0 0 3 3 3 0 Transcriptional regulator PadR-like family TBPIP PF07106.13 KFM77602.1 - 0.21 11.5 6.7 6.1 6.9 0.4 3.4 3 0 0 3 3 3 0 TBPIP/Hop2 winged helix domain SecG PF03840.14 KFM77604.1 - 0.053 13.6 0.2 0.065 13.3 0.2 1.2 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Methyltr_RsmB-F PF01189.17 KFM77605.1 - 1e-08 35.1 1.3 1.5e-08 34.5 0.1 2.0 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KFM77605.1 - 5.8e-08 33.1 0.0 1.8e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FTA4 PF13093.6 KFM77605.1 - 0.0068 16.3 2.7 0.0068 16.3 2.7 2.2 1 1 0 2 2 2 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Phage_Nu1 PF07471.12 KFM77605.1 - 2.9 7.7 6.8 0.19 11.5 1.2 1.9 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 Neur_chan_memb PF02932.16 KFM77606.1 - 1.8e-71 241.0 1.2 2.8e-71 240.3 1.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM77606.1 - 5.8e-21 74.9 0.5 9.1e-21 74.3 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFM77607.1 - 8.6e-80 267.2 0.5 1.1e-79 266.9 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM77607.1 - 6.8e-77 258.7 0.0 1.1e-76 258.1 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2070 PF09843.9 KFM77607.1 - 9.1 4.4 8.9 13 3.9 8.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SART-1 PF03343.13 KFM77608.1 - 2.4e-38 132.1 17.6 2.7e-38 132.0 17.6 1.0 1 0 0 1 1 1 1 SART-1 family Fcf2 PF08698.11 KFM77608.1 - 0.076 13.4 3.1 0.42 11.0 0.3 2.2 2 0 0 2 2 2 0 Fcf2 pre-rRNA processing SART-1 PF03343.13 KFM77609.1 - 7.4e-09 34.7 3.7 7.4e-09 34.7 3.7 1.0 1 0 0 1 1 1 1 SART-1 family SART-1 PF03343.13 KFM77610.1 - 3.3e-51 174.6 7.5 3.9e-51 174.4 7.5 1.1 1 0 0 1 1 1 1 SART-1 family DDE_1 PF03184.19 KFM77611.1 - 1e-40 139.3 0.1 1.9e-40 138.4 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM77611.1 - 6.9e-15 54.8 0.3 1.8e-14 53.5 0.3 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM77611.1 - 9.2e-06 25.2 2.7 2.9e-05 23.6 2.7 1.9 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFM77611.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.16 KFM77611.1 - 0.03 14.1 0.0 0.089 12.6 0.0 1.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Ada3 PF10198.9 KFM77611.1 - 0.1 12.7 0.9 0.25 11.5 0.3 1.9 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 Ldl_recept_a PF00057.18 KFM77612.1 - 0.0034 17.6 2.0 0.0079 16.4 2.0 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Ig_3 PF13927.6 KFM77613.1 - 1.1e-09 38.8 0.0 1.4e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM77613.1 - 1.4e-09 37.9 0.0 1.7e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM77613.1 - 3.6e-08 33.5 0.0 5.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM77613.1 - 8.9e-07 29.2 0.0 1.2e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 KFM77613.1 - 0.0032 17.8 0.0 0.0094 16.3 0.0 1.7 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 KFM77613.1 - 0.011 15.8 0.3 0.62 10.3 0.1 2.7 1 1 2 3 3 3 0 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM77613.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFM77614.1 - 3.1e-17 62.4 0.0 4.3e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM77614.1 - 3.3e-16 59.6 0.0 2e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM77614.1 - 1.6e-14 53.9 0.0 2e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM77614.1 - 7.2e-10 39.1 0.0 1.2e-05 25.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM77614.1 - 1.4e-05 25.2 0.1 0.09 13.0 0.0 3.1 2 1 0 3 3 3 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM77614.1 - 1.7e-05 25.1 0.0 0.00096 19.5 0.0 2.4 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM77614.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_4 PF16680.5 KFM77614.1 - 0.068 13.4 0.0 0.46 10.8 0.0 2.2 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain DUF4307 PF14155.6 KFM77614.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Ig_3 PF13927.6 KFM77615.1 - 1.2e-16 61.0 0.1 2.1e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM77615.1 - 1e-14 54.3 0.0 1.8e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM77615.1 - 2.1e-13 50.4 0.0 1.5e-08 34.8 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM77615.1 - 5.4e-13 48.9 0.1 3.3e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM77615.1 - 1.5e-05 25.1 0.6 0.028 14.6 0.1 3.0 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM77615.1 - 0.0036 17.7 0.1 0.055 13.9 0.0 2.5 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM77615.1 - 0.0068 15.9 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain C1-set PF07654.15 KFM77615.1 - 0.13 12.6 0.0 0.4 11.1 0.0 1.9 2 1 0 2 2 2 0 Immunoglobulin C1-set domain I-set PF07679.16 KFM77616.1 - 2.3e-06 27.6 0.0 2.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFM77616.1 - 1.1e-05 25.5 0.0 1.2e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM77616.1 - 1.4e-05 25.6 0.0 1.8e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM77616.1 - 0.00014 21.9 0.0 0.00015 21.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM77616.1 - 0.00045 20.5 0.0 0.00049 20.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_4 PF16680.5 KFM77616.1 - 0.0055 17.0 0.0 0.0061 16.8 0.0 1.1 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Herpes_gE PF02480.16 KFM77616.1 - 0.064 12.0 0.0 0.064 12.0 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ig_6 PF18452.1 KFM77616.1 - 0.07 12.7 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain fn3 PF00041.21 KFM77617.1 - 6.2e-49 164.3 13.6 2e-16 60.1 0.6 3.9 4 0 0 4 4 4 3 Fibronectin type III domain I-set PF07679.16 KFM77617.1 - 1.9e-14 53.5 0.3 1.8e-13 50.3 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM77617.1 - 4.7e-11 43.1 0.3 8.4e-10 39.1 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 KFM77617.1 - 1.5e-07 31.5 0.0 3.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Interfer-bind PF09294.10 KFM77617.1 - 4.5e-07 30.1 0.0 0.073 13.4 0.0 3.3 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Ig_2 PF13895.6 KFM77617.1 - 1.7e-05 25.0 0.0 9.9e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM77617.1 - 0.0001 22.8 7.7 0.8 10.3 0.1 4.0 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFM77617.1 - 0.00035 20.7 0.0 0.0035 17.5 0.0 2.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Mid1 PF12929.7 KFM77617.1 - 0.04 13.1 0.1 0.41 9.8 0.0 2.1 2 0 0 2 2 2 0 Stretch-activated Ca2+-permeable channel component TMEM154 PF15102.6 KFM77617.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF2369 PF10179.9 KFM77617.1 - 0.065 13.6 0.3 4.7 7.7 0.0 3.1 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2369) TNFR_16_TM PF18422.1 KFM77617.1 - 0.16 11.9 2.7 0.32 11.0 2.7 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain SPRY PF00622.28 KFM77619.1 - 8.9e-20 71.0 0.0 1.3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 SPRY domain dsrm PF00035.26 KFM77620.1 - 1.2e-45 154.0 2.9 2.9e-12 47.1 0.1 5.8 5 1 0 5 5 5 4 Double-stranded RNA binding motif Staufen_C PF16482.5 KFM77620.1 - 3.2e-37 127.1 0.4 8.3e-35 119.3 0.0 3.8 5 0 0 5 5 5 1 Staufen C-terminal domain DND1_DSRM PF14709.7 KFM77620.1 - 1e-06 28.9 1.6 0.24 11.7 0.0 5.7 5 1 0 5 5 5 2 double strand RNA binding domain from DEAD END PROTEIN 1 MRP-S26 PF14943.6 KFM77620.1 - 0.034 14.1 0.1 0.08 12.9 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PRP8_domainIV PF12134.8 KFM77620.1 - 0.12 12.0 0.4 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 PRP8 domain IV core PAF-AH_p_II PF03403.13 KFM77621.1 - 8.9e-91 304.2 0.0 8.2e-49 166.1 0.0 2.0 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFM77621.1 - 1e-07 31.2 0.0 8e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KFM77621.1 - 4.6e-05 22.8 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KFM77621.1 - 6.5e-05 22.1 0.0 0.0015 17.6 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.7 KFM77621.1 - 0.0002 22.0 0.0 0.0023 18.6 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM77621.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PUL PF08324.11 KFM77622.1 - 3.5e-34 118.3 0.9 4.9e-34 117.8 0.9 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 KFM77622.1 - 1.7e-31 107.8 19.5 3.4e-06 27.7 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat PFU PF09070.11 KFM77622.1 - 3.8e-15 56.1 1.6 6.9e-15 55.3 1.6 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.6 KFM77622.1 - 5.5e-05 23.2 0.0 0.4 10.7 0.0 4.0 3 1 2 6 6 6 2 Ciliary BBSome complex subunit 2, middle region Macin PF14865.6 KFM77622.1 - 0.12 12.9 0.4 0.48 11.0 0.4 2.0 1 0 0 1 1 1 0 Macin Apolipoprotein PF01442.18 KFM77623.1 - 1.1e-12 48.2 59.4 6.6e-11 42.4 26.3 2.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFM77623.1 - 3.3e-10 40.2 8.4 0.00015 21.8 1.7 3.7 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 KFM77623.1 - 5.9e-07 29.7 39.9 0.0014 18.7 16.4 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF1640) Phasin PF05597.11 KFM77623.1 - 4.4e-05 23.5 43.8 0.031 14.3 6.6 4.1 1 1 3 4 4 4 3 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoLp-III PF07464.11 KFM77623.1 - 8.9e-05 22.6 48.7 0.0011 19.1 29.1 2.4 1 1 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 KFM77623.1 - 0.00024 21.6 32.6 0.2 12.2 9.0 3.9 1 1 3 5 5 5 5 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 KFM77623.1 - 0.00031 20.8 42.2 0.0046 17.0 9.1 3.8 1 1 3 4 4 4 2 Protein of unknown function (DUF1664) Prominin PF05478.11 KFM77623.1 - 0.00042 18.4 28.3 0.0014 16.7 27.4 1.8 1 1 0 1 1 1 1 Prominin DUF4795 PF16043.5 KFM77623.1 - 0.00044 19.9 40.9 0.16 11.6 12.5 3.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) ApoO PF09769.9 KFM77623.1 - 0.00046 20.1 18.1 0.3 11.1 0.7 4.4 1 1 1 3 3 3 1 Apolipoprotein O CdvA PF18822.1 KFM77623.1 - 0.0008 19.2 43.3 0.081 12.8 1.4 5.3 1 1 2 3 3 2 2 CdvA-like coiled-coil domain SF-assemblin PF06705.11 KFM77623.1 - 0.00099 18.5 42.5 0.0082 15.5 31.1 2.3 1 1 1 2 2 2 2 SF-assemblin/beta giardin DUF3584 PF12128.8 KFM77623.1 - 0.0019 15.8 8.4 0.0019 15.8 8.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3584) DUF842 PF05811.13 KFM77623.1 - 0.013 15.2 31.5 0.32 10.7 10.8 3.5 1 1 2 3 3 3 0 Eukaryotic protein of unknown function (DUF842) HSBP1 PF06825.12 KFM77623.1 - 0.013 15.3 13.9 0.43 10.5 0.0 4.7 2 2 0 3 3 3 0 Heat shock factor binding protein 1 PIN_8 PF18476.1 KFM77623.1 - 0.021 14.7 31.8 0.81 9.5 7.2 2.3 1 1 1 2 2 2 0 PIN like domain HIP1_clath_bdg PF16515.5 KFM77623.1 - 0.022 15.4 3.2 0.022 15.4 3.2 4.3 1 1 1 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RHD3 PF05879.12 KFM77623.1 - 0.048 11.8 26.4 0.064 11.4 26.4 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Muted PF14942.6 KFM77623.1 - 0.05 13.9 44.5 0.071 13.5 6.0 2.8 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein T3SS_needle_F PF09392.10 KFM77623.1 - 0.051 13.8 28.8 0.67 10.2 0.8 6.1 2 2 3 5 5 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Strep_SA_rep PF06696.11 KFM77623.1 - 0.069 13.2 20.5 24 5.1 0.1 7.0 4 1 3 7 7 6 0 Streptococcal surface antigen repeat Syntaxin_2 PF14523.6 KFM77623.1 - 0.085 13.2 27.1 0.88 10.0 8.7 4.0 2 2 2 4 4 4 0 Syntaxin-like protein Mitofilin PF09731.9 KFM77623.1 - 0.11 11.3 47.3 0.61 8.9 47.3 1.9 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Mating_N PF12731.7 KFM77623.1 - 0.12 12.5 6.2 5.6 7.1 0.6 3.7 3 2 0 3 3 3 0 Mating-type protein beta 1 DUF2884 PF11101.8 KFM77623.1 - 0.18 11.3 40.2 0.58 9.6 18.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2884) Peptidase_M75 PF09375.10 KFM77623.1 - 0.18 11.2 17.9 0.33 10.4 11.0 2.6 1 1 1 2 2 2 0 Imelysin EzrA PF06160.12 KFM77623.1 - 0.2 9.8 36.2 0.061 11.5 32.8 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Fzo_mitofusin PF04799.13 KFM77623.1 - 0.2 11.2 35.1 0.14 11.7 4.7 3.9 1 1 2 3 3 3 0 fzo-like conserved region IFT57 PF10498.9 KFM77623.1 - 0.23 10.4 41.2 0.82 8.6 41.2 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 IL32 PF15225.6 KFM77623.1 - 0.23 11.8 11.8 1.7 9.1 2.9 2.9 1 1 2 3 3 3 0 Interleukin 32 Phage_Mu_Gam PF07352.12 KFM77623.1 - 0.25 11.3 38.5 1.3 8.9 3.8 5.0 1 1 4 5 5 5 0 Bacteriophage Mu Gam like protein CwsA PF10814.8 KFM77623.1 - 0.26 11.5 18.7 0.81 9.9 1.8 3.6 1 1 1 3 3 3 0 Cell wall synthesis protein CwsA Syntaxin PF00804.25 KFM77623.1 - 0.27 10.9 39.5 1.4 8.5 19.5 3.3 1 1 2 3 3 3 0 Syntaxin Cache_3-Cache_2 PF17201.4 KFM77623.1 - 0.33 10.2 25.2 0.55 9.5 6.9 3.1 1 1 2 3 3 3 0 Cache 3/Cache 2 fusion domain DUF885 PF05960.11 KFM77623.1 - 0.34 10.5 21.3 0.52 9.9 21.3 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF4635 PF15466.6 KFM77623.1 - 0.37 10.3 22.5 0.87 9.1 4.9 3.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4635) Spore_III_AB PF09548.10 KFM77623.1 - 0.41 10.7 21.3 18 5.4 18.0 2.9 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) HalX PF08663.10 KFM77623.1 - 0.42 11.0 12.3 3.5 8.0 0.3 4.8 2 2 1 3 3 3 0 HalX domain DUF4407 PF14362.6 KFM77623.1 - 0.5 9.7 31.1 0.49 9.7 13.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) YtxH PF12732.7 KFM77623.1 - 0.5 10.9 50.2 1.4 9.5 4.5 5.0 1 1 1 2 2 1 0 YtxH-like protein DUF1451 PF07295.11 KFM77623.1 - 0.55 10.3 34.5 2.1 8.3 11.4 3.2 1 1 2 3 3 3 0 Zinc-ribbon containing domain COG2 PF06148.11 KFM77623.1 - 0.61 10.2 46.1 0.64 10.1 2.3 5.1 1 1 3 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 KFM77623.1 - 0.65 10.5 31.7 30 5.1 10.5 5.0 1 1 1 2 2 1 0 Nucleopolyhedrovirus P10 protein Tweety PF04906.13 KFM77623.1 - 0.88 8.2 21.8 0.053 12.2 3.0 2.6 1 1 1 2 2 2 0 Tweety Peptidase_S64 PF08192.11 KFM77623.1 - 0.88 8.0 31.7 2.3 6.6 31.7 1.6 1 1 0 1 1 1 0 Peptidase family S64 FAM184 PF15665.5 KFM77623.1 - 1.2 8.9 48.4 4.9 6.9 8.6 2.6 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B AIP3 PF03915.13 KFM77623.1 - 1.2 8.2 40.9 21 4.0 40.9 2.2 1 1 0 1 1 1 0 Actin interacting protein 3 OmpH PF03938.14 KFM77623.1 - 1.3 9.3 51.7 4.9e+02 1.0 33.0 3.0 1 1 1 2 2 1 0 Outer membrane protein (OmpH-like) DUF148 PF02520.17 KFM77623.1 - 1.8 8.7 39.9 2 8.6 12.8 4.1 1 1 3 4 4 4 0 Domain of unknown function DUF148 Mer2 PF09074.10 KFM77623.1 - 1.9 8.2 36.7 0.94 9.3 7.0 2.8 1 1 1 2 2 2 0 Mer2 Focal_AT PF03623.13 KFM77623.1 - 2.6 8.0 32.9 2 8.4 4.9 3.3 1 1 2 3 3 3 0 Focal adhesion targeting region BshC PF10079.9 KFM77623.1 - 2.6 6.7 35.2 1.3 7.7 3.8 2.9 1 1 2 3 3 3 0 Bacillithiol biosynthesis BshC FliT PF05400.13 KFM77623.1 - 2.6 8.9 20.7 3 8.7 3.6 4.0 1 1 1 3 3 3 0 Flagellar protein FliT PKK PF12474.8 KFM77623.1 - 2.7 8.1 44.3 0.59 10.2 32.1 3.3 2 2 1 3 3 3 0 Polo kinase kinase dCache_2 PF08269.11 KFM77623.1 - 3.1 6.9 36.2 4.9 6.2 7.0 3.3 1 1 2 3 3 3 0 Cache domain PLC-beta_C PF08703.10 KFM77623.1 - 3.2 7.7 47.0 1.4 8.9 15.0 3.4 1 1 1 2 2 2 0 PLC-beta C terminal DUF1690 PF07956.11 KFM77623.1 - 3.4 8.1 42.3 6.7 7.1 8.5 3.4 1 1 3 4 4 4 0 Protein of Unknown function (DUF1690) DUF4510 PF14971.6 KFM77623.1 - 4 7.8 18.2 9.3 6.6 10.4 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4510) DUF3511 PF12023.8 KFM77623.1 - 4.4 7.2 12.8 8.9 6.2 0.9 4.7 2 1 3 5 5 4 0 Domain of unknown function (DUF3511) WXG100 PF06013.12 KFM77623.1 - 6.7 7.0 28.0 48 4.3 6.2 5.3 2 2 2 4 4 4 0 Proteins of 100 residues with WXG DUF4854 PF16146.5 KFM77623.1 - 6.7 7.1 34.3 4.8 7.6 4.2 5.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4854) DUF1054 PF06335.12 KFM77623.1 - 7.2 6.5 24.8 4.7 7.1 0.1 3.8 1 1 4 5 5 5 0 Protein of unknown function (DUF1054) DUF5063 PF16702.5 KFM77623.1 - 8.5 6.7 14.7 1.3 9.4 2.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5063) Mt_ATP-synt_B PF05405.14 KFM77623.1 - 8.5 6.0 37.1 0.33 10.6 16.2 3.4 1 1 1 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AAA_32 PF13654.6 KFM77623.1 - 8.6 5.0 38.1 15 4.2 10.3 2.3 1 1 1 2 2 2 0 AAA domain Lipoprotein_2 PF00921.17 KFM77623.1 - 9 5.8 44.7 0.43 10.1 22.1 2.3 1 1 1 2 2 2 0 Borrelia lipoprotein IGFBP PF00219.18 KFM77624.1 - 3.8e-09 37.1 22.5 6.3e-09 36.4 22.5 1.3 1 0 0 1 1 1 1 Insulin-like growth factor binding protein Cys_knot PF00007.22 KFM77625.1 - 0.014 15.7 17.8 0.032 14.5 14.7 2.6 1 1 1 2 2 2 0 Cystine-knot domain BAR PF03114.18 KFM77626.1 - 4.1e-69 232.9 2.4 5e-69 232.6 2.4 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KFM77626.1 - 2e-09 37.0 1.2 2.9e-09 36.5 1.2 1.5 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFM77626.1 - 1.5e-05 24.8 0.4 2.2e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 BAR domain of APPL family IMD PF08397.11 KFM77626.1 - 0.013 14.9 0.3 0.022 14.2 0.3 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Sec63 PF02889.16 KFM77627.1 - 4.9e-76 255.3 0.5 1.2e-75 254.0 0.5 1.7 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KFM77627.1 - 1.1e-40 139.3 2.5 7e-28 97.6 1.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KFM77627.1 - 1.3e-19 70.8 0.7 4.9e-12 46.2 0.1 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 KFM77627.1 - 5.9e-12 45.7 0.9 2e-11 44.1 0.9 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain Helicase_C PF00271.31 KFM77627.1 - 1.1e-08 35.4 0.6 9.3e-08 32.4 0.1 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain T2SSE PF00437.20 KFM77627.1 - 0.00015 20.9 0.0 0.54 9.3 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 KFM77627.1 - 0.00015 22.1 1.0 0.027 14.8 0.4 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFM77627.1 - 0.00035 20.9 1.2 0.0052 17.1 0.2 3.1 3 1 0 3 3 2 1 AAA domain PhoH PF02562.16 KFM77627.1 - 0.00088 18.8 0.2 0.71 9.3 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_7 PF12775.7 KFM77627.1 - 0.0045 16.5 1.5 5.7 6.4 0.0 3.4 3 0 0 3 3 3 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFM77627.1 - 0.0053 16.5 0.4 2.5 7.8 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFM77627.1 - 0.072 12.5 0.0 6.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.21 KFM77627.1 - 2.6 7.5 10.3 0.18 11.3 0.1 3.4 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 KFM77627.1 - 4.2 7.1 7.1 2.2 8.0 0.1 3.4 4 0 0 4 4 4 0 AAA domain Sec63 PF02889.16 KFM77628.1 - 2e-16 60.0 0.1 3.1e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 KFM77628.1 - 1.6e-08 34.8 0.0 5.6e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain MAP7 PF05672.11 KFM77629.1 - 2e-18 66.6 92.3 2e-18 66.6 92.3 4.3 3 1 1 4 4 4 2 MAP7 (E-MAP-115) family Tmp39 PF10271.9 KFM77630.1 - 5.2e-98 328.9 22.2 1.8e-97 327.1 22.2 1.6 1 1 0 1 1 1 1 Putative transmembrane protein Ribonuclease_T2 PF00445.18 KFM77632.1 - 1.5e-16 61.2 0.1 1.8e-16 60.9 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family RNase_H PF00075.24 KFM77633.1 - 6.6e-14 52.3 0.0 1.5e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM77633.1 - 9.7e-07 28.6 0.0 2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like Antimicrobial_7 PF08102.11 KFM77633.1 - 0.077 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Scorpion antimicrobial peptide Carb_anhydrase PF00194.21 KFM77634.1 - 3.8e-69 233.1 0.1 6.7e-69 232.2 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CUB PF00431.20 KFM77635.1 - 2.1e-11 44.1 0.1 4.5e-11 43.0 0.1 1.6 1 1 0 1 1 1 1 CUB domain Thioredoxin PF00085.20 KFM77636.1 - 1e-148 484.8 19.5 9.7e-25 86.5 0.2 7.1 7 0 0 7 7 7 7 Thioredoxin Thioredoxin_2 PF13098.6 KFM77636.1 - 2e-41 140.9 11.9 5e-07 30.2 0.0 7.7 7 0 0 7 7 7 6 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFM77636.1 - 1e-32 112.1 2.6 0.00028 21.0 0.0 6.7 7 0 0 7 7 7 6 Thioredoxin-like AhpC-TSA PF00578.21 KFM77636.1 - 6.6e-28 97.1 7.2 0.00022 21.1 0.1 6.4 6 0 0 6 6 6 6 AhpC/TSA family OST3_OST6 PF04756.13 KFM77636.1 - 2.1e-27 96.2 13.8 7.4e-07 28.8 0.0 6.9 7 1 1 8 8 8 5 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFM77636.1 - 1.5e-20 73.4 11.3 0.0061 16.9 0.0 9.8 7 3 3 10 10 10 5 Thioredoxin-like Redoxin PF08534.10 KFM77636.1 - 2.1e-14 53.4 6.9 0.092 12.5 0.1 6.3 6 0 0 6 6 6 5 Redoxin Thioredoxin_6 PF13848.6 KFM77636.1 - 2.8e-13 50.2 7.2 0.00046 20.2 0.1 6.6 7 0 0 7 7 7 3 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KFM77636.1 - 7.5e-09 35.4 5.4 0.39 10.5 0.1 6.2 6 0 0 6 6 6 2 Thioredoxin Glutaredoxin PF00462.24 KFM77636.1 - 1.6e-08 34.7 19.8 0.81 9.9 0.2 7.0 6 1 0 6 6 6 4 Glutaredoxin HyaE PF07449.11 KFM77636.1 - 9.9e-08 31.9 0.0 1.5 8.8 0.0 5.3 5 0 0 5 5 5 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KFM77636.1 - 4.2e-07 30.0 18.7 0.34 10.7 0.1 7.7 7 2 1 8 8 8 3 F plasmid transfer operon protein ProRS-C_1 PF09180.11 KFM77636.1 - 1.1 9.5 10.8 30 4.9 0.1 6.0 7 0 0 7 7 7 0 Prolyl-tRNA synthetase, C-terminal Thioredoxin_4 PF13462.6 KFM77636.1 - 1.2 9.3 16.0 12 6.0 0.3 5.6 6 0 0 6 6 6 0 Thioredoxin Mito_fiss_reg PF05308.11 KFM77636.1 - 1.4 8.9 7.5 9.1 6.3 0.1 3.3 3 0 0 3 3 3 0 Mitochondrial fission regulator OMP_b-brl PF13505.6 KFM77638.1 - 2e-20 73.7 84.6 0.062 13.4 0.6 14.7 14 0 0 14 14 14 12 Outer membrane protein beta-barrel domain MspA PF09203.11 KFM77638.1 - 1.4e-16 60.8 111.3 0.043 13.7 1.7 15.9 14 2 0 14 14 14 11 MspA DUF1943 PF09172.11 KFM77638.1 - 2.2e-08 33.7 0.0 4.6 6.4 0.0 9.5 11 1 0 11 11 11 1 Domain of unknown function (DUF1943) FUN14 PF04930.15 KFM77638.1 - 5.8e-07 29.8 21.9 30 5.1 0.1 12.5 13 0 0 13 13 13 0 FUN14 family RP1-2 PF12042.8 KFM77638.1 - 0.02 14.8 55.4 1.5 8.7 0.1 16.2 16 0 0 16 16 16 0 Tubuliform egg casing silk strands structural domain CM_2 PF01817.21 KFM77638.1 - 0.091 13.1 15.2 22 5.5 0.0 7.5 10 0 0 10 10 10 0 Chorismate mutase type II PAC4 PF16093.5 KFM77638.1 - 0.48 10.6 29.7 22 5.4 0.0 10.5 13 0 0 13 13 13 0 Proteasome assembly chaperone 4 TusA PF01206.17 KFM77638.1 - 0.72 9.7 7.8 35 4.3 0.0 6.5 9 0 0 9 9 9 0 Sulfurtransferase TusA Phage_Coat_Gp8 PF05371.12 KFM77638.1 - 1.1 9.1 10.5 1.6e+02 2.2 0.0 7.3 9 0 0 9 9 9 0 Phage major coat protein, Gp8 OMP_b-brl_2 PF13568.6 KFM77638.1 - 3.7 7.5 9.5 2.2e+02 1.7 0.1 8.2 9 0 0 9 9 9 0 Outer membrane protein beta-barrel domain RP1-2 PF12042.8 KFM77639.1 - 5.7e-14 52.3 39.9 1.2e-10 41.5 1.6 4.7 4 1 0 4 4 4 3 Tubuliform egg casing silk strands structural domain Alpha-amylase PF00128.24 KFM77641.1 - 5.7e-11 42.6 0.7 7.1e-11 42.2 0.7 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3114 PF11311.8 KFM77641.1 - 0.011 15.3 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) Ank_4 PF13637.6 KFM77642.1 - 1.7e-14 54.0 2.5 8.3e-11 42.2 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM77642.1 - 8.1e-13 48.3 0.6 4.7e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM77642.1 - 4.9e-12 46.3 0.4 1.1e-11 45.1 0.2 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM77642.1 - 1.6e-11 44.1 1.2 0.001 19.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFM77642.1 - 1.1e-10 40.8 2.4 0.00012 22.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat RVT_2 PF07727.14 KFM77643.1 - 3.4e-05 23.6 0.2 3.8e-05 23.4 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LIM PF00412.22 KFM77644.1 - 4.4e-70 231.8 76.2 1.8e-13 50.5 7.9 6.5 6 1 0 6 6 6 6 LIM domain PET PF06297.14 KFM77644.1 - 1.4e-26 92.6 0.1 2.7e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 PET Domain DUF3756 PF12581.8 KFM77646.1 - 0.14 12.1 0.1 0.34 10.9 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3756) TIL PF01826.17 KFM77647.1 - 0 1073.0 811.7 2.3e-14 53.4 19.2 32.1 32 0 0 32 32 32 32 Trypsin Inhibitor like cysteine rich domain SAM_3 PF18016.1 KFM77648.1 - 4.2e-20 71.3 0.1 8.9e-20 70.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PTB PF08416.13 KFM77648.1 - 3.3e-16 59.6 0.0 9.5e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotyrosine-binding domain SH3_1 PF00018.28 KFM77648.1 - 2.4e-06 27.1 0.0 5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM77648.1 - 0.0013 18.4 0.2 0.0059 16.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain hSH3 PF14603.6 KFM77648.1 - 0.065 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Helically-extended SH3 domain ResIII PF04851.15 KFM77651.1 - 3.2e-10 40.3 0.4 5.4e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM77651.1 - 2.5e-07 30.7 0.0 3.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase PsaD PF02531.16 KFM77651.1 - 0.07 12.7 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 PsaD Ank_2 PF12796.7 KFM77652.1 - 6.9e-06 26.6 0.0 7.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM77652.1 - 0.00056 20.2 0.0 0.23 12.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFM77652.1 - 0.0011 19.5 0.0 0.0016 19.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) 2-Hacid_dh PF00389.30 KFM77654.1 - 1.2e-28 99.5 0.0 1.3e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 KFM77654.1 - 1.3e-08 34.4 0.1 2e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KFM77654.1 - 0.24 11.9 0.8 18 5.8 0.1 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF4371 PF14291.6 KFM77655.1 - 0.0011 18.7 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) EphA2_TM PF14575.6 KFM77657.1 - 0.16 12.9 0.1 0.16 12.9 0.1 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 KFM77657.1 - 0.72 9.7 2.0 0.77 9.6 2.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor RT_RNaseH_2 PF17919.1 KFM77659.1 - 8.1e-25 86.8 0.1 1.8e-24 85.7 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM77659.1 - 3e-14 53.2 0.0 8.5e-14 51.7 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DDE_3 PF13358.6 KFM77660.1 - 4.2e-16 59.0 0.1 3.8e-15 55.9 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM77660.1 - 1.4e-10 41.2 1.0 2.9e-10 40.2 1.0 1.6 1 0 0 1 1 1 1 Transposase SET PF00856.28 KFM77664.1 - 2.2e-18 67.2 0.3 2.2e-18 67.2 0.3 4.0 2 2 0 2 2 2 1 SET domain N-SET PF11764.8 KFM77664.1 - 1.6e-14 54.4 4.4 1.6e-14 54.4 4.4 4.6 2 2 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.22 KFM77665.1 - 4.3e-11 42.5 0.0 6.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BolA PF01722.18 KFM77666.1 - 3.1e-14 53.0 0.1 5.4e-14 52.2 0.1 1.4 1 1 0 1 1 1 1 BolA-like protein Pkinase PF00069.25 KFM77667.1 - 2.6e-05 23.7 0.0 3.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain 7tm_1 PF00001.21 KFM77668.1 - 1.9e-59 201.2 6.6 2.4e-59 200.8 6.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM77668.1 - 2.8e-10 40.0 7.4 4.3e-10 39.4 7.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFM77668.1 - 1.1e-06 28.6 9.6 1.6e-06 28.1 5.3 2.1 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFM77668.1 - 6.3e-06 26.0 11.2 6.3e-06 26.0 11.2 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Cyclin_C PF02984.19 KFM77669.1 - 0.021 14.9 0.2 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain Claudin_2 PF13903.6 KFM77670.1 - 1.6e-36 125.9 0.1 2.1e-36 125.5 0.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFM77670.1 - 0.00022 21.2 10.4 0.02 14.8 10.4 3.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 KFM77670.1 - 0.0011 18.6 9.7 0.0033 17.1 7.5 2.5 1 1 1 2 2 2 1 SUR7/PalI family DUF373 PF04123.13 KFM77670.1 - 0.011 15.3 0.7 0.02 14.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4064 PF13273.6 KFM77670.1 - 0.014 15.6 1.1 4.1 7.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF1772 PF08592.11 KFM77670.1 - 0.075 13.4 0.4 1.3 9.4 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) DUF2721 PF11026.8 KFM77670.1 - 0.076 12.9 4.8 0.36 10.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Clc-like PF07062.12 KFM77670.1 - 0.85 9.0 8.7 0.63 9.5 0.1 2.7 2 1 1 3 3 3 0 Clc-like DUF4282 PF14110.6 KFM77670.1 - 8.9 7.1 9.6 0.34 11.7 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) NADH_B2 PF14813.6 KFM77671.1 - 3.9e-24 84.2 8.5 4.8e-24 83.9 8.5 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 U3snoRNP10 PF12397.8 KFM77672.1 - 6.8e-14 52.2 2.8 1.4e-13 51.2 2.8 1.5 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 10 BP28CT PF08146.12 KFM77674.1 - 1.4e-30 106.2 6.3 1.4e-30 106.2 6.3 2.7 3 0 0 3 3 3 1 BP28CT (NUC211) domain Tti2 PF10521.9 KFM77674.1 - 0.0059 16.2 4.2 0.013 15.1 0.2 2.9 3 0 0 3 3 3 1 Tti2 family HEAT PF02985.22 KFM77674.1 - 0.015 15.5 0.5 0.59 10.5 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 KFM77674.1 - 0.016 15.6 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats NUC173 PF08161.12 KFM77674.1 - 0.028 14.1 4.3 2.1 7.9 0.0 3.7 3 1 1 4 4 4 0 NUC173 domain Vac14_Fab1_bd PF12755.7 KFM77674.1 - 0.073 13.7 3.5 0.7 10.5 0.0 3.4 3 2 0 3 3 3 0 Vacuolar 14 Fab1-binding region Granulin PF00396.18 KFM77675.1 - 2.5e-12 46.9 16.9 2.5e-12 46.9 16.9 1.9 1 1 1 2 2 2 2 Granulin Toxin_18 PF08087.11 KFM77675.1 - 0.0028 17.6 1.3 0.0028 17.6 1.3 2.6 2 1 0 2 2 2 1 Conotoxin O-superfamily Ceramidase_alk PF04734.13 KFM77675.1 - 0.9 8.1 4.1 1 8.0 4.1 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal Actin PF00022.19 KFM77676.1 - 1e-101 340.6 0.0 4.2e-101 338.5 0.0 1.7 1 1 0 1 1 1 1 Actin RhoGAP PF00620.27 KFM77677.1 - 2.4e-44 150.8 0.0 5.1e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.18 KFM77677.1 - 1.7e-18 67.2 4.1 2.8e-18 66.4 4.1 1.4 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KFM77677.1 - 0.0011 18.1 2.3 0.0011 18.1 2.3 1.7 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Nexin_C PF08628.12 KFM77679.1 - 3.9e-08 33.9 0.1 8.5e-08 32.8 0.1 1.6 1 1 0 1 1 1 1 Sorting nexin C terminal EcoEI_R_C PF08463.10 KFM77679.1 - 0.0028 17.8 0.4 0.0044 17.2 0.2 1.4 2 0 0 2 2 2 1 EcoEI R protein C-terminal PXA PF02194.15 KFM77680.1 - 8.6e-17 61.7 0.2 2.2e-16 60.3 0.2 1.7 1 0 0 1 1 1 1 PXA domain RGS PF00615.19 KFM77680.1 - 1.3e-16 60.9 1.2 2.7e-16 59.9 1.2 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain PX PF00787.24 KFM77680.1 - 5.1e-14 52.2 0.7 5.1e-14 52.2 0.7 1.8 2 0 0 2 2 2 1 PX domain PXA PF02194.15 KFM77681.1 - 0.016 15.2 0.1 0.024 14.6 0.1 1.3 1 0 0 1 1 1 0 PXA domain Dimer_Tnp_hAT PF05699.14 KFM77682.1 - 9e-12 44.6 0.0 2.1e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KFM77682.1 - 2.2e-06 27.6 0.8 0.048 13.5 0.4 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) TGT PF01702.18 KFM77682.1 - 0.096 11.8 0.0 0.27 10.3 0.0 1.8 1 1 1 2 2 2 0 Queuine tRNA-ribosyltransferase Propep_M14 PF02244.16 KFM77682.1 - 0.28 11.6 3.1 4.1 7.9 0.7 3.3 4 0 0 4 4 4 0 Carboxypeptidase activation peptide Aldedh PF00171.22 KFM77685.1 - 1.7e-171 570.8 0.1 2e-171 570.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF730 PF05325.11 KFM77685.1 - 0.08 13.0 0.0 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF730) LSM PF01423.22 KFM77686.1 - 1.8e-16 59.6 0.0 2.1e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFM77686.1 - 0.0023 18.0 0.1 0.0029 17.7 0.1 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain HTH_32 PF13565.6 KFM77687.1 - 0.001 19.6 0.6 0.0014 19.2 0.6 1.2 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 KFM77687.1 - 0.0049 16.7 0.4 0.11 12.4 0.1 2.2 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KFM77687.1 - 0.0067 16.4 0.7 0.0084 16.1 0.1 1.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain PAX PF00292.18 KFM77687.1 - 0.0091 15.9 0.1 0.1 12.5 0.0 1.8 1 1 1 2 2 2 1 'Paired box' domain HTH_23 PF13384.6 KFM77687.1 - 0.012 15.4 1.7 0.017 14.9 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM77687.1 - 0.018 15.2 0.2 0.041 14.1 0.2 1.5 1 0 0 1 1 1 0 Transposase HTH_24 PF13412.6 KFM77687.1 - 0.043 13.4 0.2 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HeLo PF14479.6 KFM77687.1 - 0.054 13.3 0.2 0.064 13.1 0.2 1.0 1 0 0 1 1 1 0 Prion-inhibition and propagation DDE_Tnp_1_7 PF13843.6 KFM77688.1 - 2e-71 241.1 0.6 2.4e-71 240.9 0.6 1.1 1 0 0 1 1 1 1 Transposase IS4 zf-B_box PF00643.24 KFM77688.1 - 0.016 15.4 7.2 0.037 14.2 7.2 1.6 1 0 0 1 1 1 0 B-box zinc finger Tnp_zf-ribbon_2 PF13842.6 KFM77688.1 - 0.81 10.6 12.5 3.6 8.5 12.5 2.2 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-C2H2_12 PF18658.1 KFM77689.1 - 0.0024 17.4 0.2 0.0046 16.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger C2H2-type zf-BED PF02892.15 KFM77689.1 - 0.0035 17.3 2.5 0.006 16.6 2.5 1.4 1 0 0 1 1 1 1 BED zinc finger GAGA PF09237.11 KFM77689.1 - 0.013 15.3 0.2 0.032 14.0 0.2 1.6 1 0 0 1 1 1 0 GAGA factor DUF5631 PF18645.1 KFM77689.1 - 0.033 14.6 0.0 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5631) zf-H2C2_5 PF13909.6 KFM77689.1 - 0.13 12.1 1.6 0.28 11.0 1.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Gln-synt_C PF00120.24 KFM77690.1 - 5.4e-18 65.1 0.0 2e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFM77690.1 - 2.9e-12 46.1 0.0 5.2e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4162 PF13732.6 KFM77691.1 - 0.00032 21.3 0.0 0.00048 20.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) ABC_tran PF00005.27 KFM77692.1 - 5.3e-15 56.1 0.0 5.5e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 KFM77692.1 - 0.015 15.2 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KFM77692.1 - 0.13 12.4 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 KFM77693.1 - 4.4e-24 85.2 13.5 4.7e-24 85.1 13.5 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3894 PF13033.6 KFM77693.1 - 0.0031 17.6 1.1 0.0031 17.6 1.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3894) CitMHS PF03600.16 KFM77693.1 - 2.2 7.4 6.2 2.6 7.2 6.2 1.1 1 0 0 1 1 1 0 Citrate transporter AAA_21 PF13304.6 KFM77694.1 - 3.4e-07 30.4 0.0 9.3e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KFM77694.1 - 1e-06 29.3 0.0 1.9e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KFM77694.1 - 0.00023 20.4 1.8 0.0042 16.2 1.8 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KFM77695.1 - 2.6e-09 37.7 0.1 3.5e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KFM77695.1 - 0.0038 17.8 0.2 0.0051 17.3 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KFM77695.1 - 0.025 14.3 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFM77695.1 - 0.036 13.8 0.1 0.059 13.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain MukB PF04310.12 KFM77695.1 - 0.036 13.9 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 MukB N-terminal RsgA_GTPase PF03193.16 KFM77695.1 - 0.045 13.6 0.1 0.067 13.1 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 KFM77695.1 - 0.15 11.9 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 KFM77695.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KFM77695.1 - 0.28 10.9 0.0 0.36 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 KFM77696.1 - 8e-16 58.1 12.0 9.2e-16 57.9 12.0 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein Glyco_hydro_59M PF17387.2 KFM77697.1 - 0.025 14.7 0.1 0.045 13.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 central domain LAS2 PF15792.5 KFM77698.1 - 0.097 13.2 0.1 0.18 12.3 0.1 1.4 1 1 0 1 1 1 0 Lung adenoma susceptibility protein 2 CTP_transf_like PF01467.26 KFM77700.1 - 1.6e-23 83.5 0.0 2.9e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Ras PF00071.22 KFM77701.1 - 3.6e-26 91.7 0.0 7.4e-26 90.7 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFM77701.1 - 1.3e-11 44.8 0.0 4.2e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM77701.1 - 1e-07 31.6 0.0 5.4e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM77701.1 - 3.9e-06 26.9 0.0 5.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM77701.1 - 5.1e-05 22.7 0.0 6.3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFM77701.1 - 0.0014 17.8 0.5 0.13 11.4 0.2 2.7 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFM77701.1 - 0.0044 16.5 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NACHT PF05729.12 KFM77701.1 - 0.0071 16.3 0.0 0.037 13.9 0.0 1.9 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 KFM77701.1 - 0.0081 16.1 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFM77701.1 - 0.0094 16.3 0.1 0.023 15.1 0.0 1.6 2 1 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.18 KFM77701.1 - 0.012 15.2 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KFM77701.1 - 0.02 15.2 0.0 0.063 13.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 KFM77701.1 - 0.03 13.7 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Viral_helicase1 PF01443.18 KFM77701.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KFM77701.1 - 0.046 13.2 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KFM77701.1 - 0.05 13.6 0.0 0.085 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFM77701.1 - 0.052 13.3 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM77701.1 - 0.096 12.9 0.0 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFM77701.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KFM77701.1 - 0.2 12.0 0.0 0.47 10.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain BTB PF00651.31 KFM77702.1 - 3.4e-23 82.0 0.0 6.1e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_11 PF16622.5 KFM77702.1 - 0.0003 20.5 0.2 0.00058 19.6 0.2 1.5 1 0 0 1 1 1 1 zinc-finger C2H2-type DNA_pol_B_2 PF03175.13 KFM77703.1 - 2.6e-07 29.9 0.0 2.7e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Elf1 PF05129.13 KFM77704.1 - 6.1e-32 109.5 2.2 6.8e-32 109.4 2.2 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_CPXG PF14255.6 KFM77704.1 - 0.2 11.6 4.0 3.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Cysteine-rich CPXCG Zn_Tnp_IS1595 PF12760.7 KFM77704.1 - 0.68 10.0 6.0 1.3 9.1 6.0 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 KFM77704.1 - 1 9.5 7.0 2.1 8.4 2.2 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger HTH_23 PF13384.6 KFM77705.1 - 5.2e-06 26.1 1.0 6.6e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM77705.1 - 6e-06 26.4 0.3 1.5e-05 25.1 0.1 1.7 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 KFM77705.1 - 7.7e-06 25.8 0.1 2.5e-05 24.2 0.0 2.0 2 1 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KFM77705.1 - 2.4e-05 24.4 0.6 3.6e-05 23.8 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 KFM77705.1 - 0.00027 20.6 1.1 0.0039 16.9 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KFM77705.1 - 0.0055 16.1 0.3 0.62 9.5 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.10 KFM77705.1 - 0.032 14.0 2.5 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Phage_NinH PF06322.11 KFM77705.1 - 0.04 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Phage NinH protein HTH_24 PF13412.6 KFM77705.1 - 0.058 13.0 0.2 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 KFM77705.1 - 0.069 13.8 1.9 0.2 12.3 0.8 2.0 1 1 1 2 2 2 0 Homeodomain-like domain HTH_31 PF13560.6 KFM77705.1 - 0.075 13.4 2.7 0.11 12.8 0.4 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM77705.1 - 0.083 12.9 0.9 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DUF1670 PF07900.11 KFM77705.1 - 0.18 11.1 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) HTH_AsnC-type PF13404.6 KFM77705.1 - 0.21 11.4 1.0 4.9 7.1 0.1 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PGM_PMM_I PF02878.16 KFM77706.1 - 5.5e-15 55.3 0.2 4.9e-08 32.8 0.0 3.1 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KFM77706.1 - 1.8e-07 31.2 0.1 5.4e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KFM77706.1 - 0.00037 20.7 0.1 0.00085 19.5 0.1 1.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III FMN_dh PF01070.18 KFM77706.1 - 0.027 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PGM_PMM_II PF02879.16 KFM77706.1 - 0.03 15.0 0.9 1.7 9.3 0.5 3.5 3 1 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Sec2p PF06428.11 KFM77709.1 - 1.5e-07 31.3 9.8 1.5e-07 31.3 9.8 2.9 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p Fez1 PF06818.15 KFM77709.1 - 1.1 9.7 8.4 0.76 10.2 5.1 2.0 2 0 0 2 2 2 0 Fez1 Spc7 PF08317.11 KFM77709.1 - 1.4 7.8 9.8 0.53 9.1 5.5 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein GMC_oxred_N PF00732.19 KFM77710.1 - 3e-46 158.2 0.0 4e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFM77710.1 - 1.9e-34 119.2 0.0 2.8e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFM77710.1 - 0.029 13.5 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain PIN_4 PF13638.6 KFM77711.1 - 7.7e-29 100.6 0.1 7.7e-29 100.6 0.1 2.4 3 0 0 3 3 3 1 PIN domain WW PF00397.26 KFM77711.1 - 9.4e-09 35.2 0.1 1.9e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 WW domain HEPN_Swt1 PF18731.1 KFM77711.1 - 0.0086 16.4 0.8 0.093 13.1 0.2 3.0 2 1 0 2 2 2 1 Swt1-like HEPN PIN_9 PF18477.1 KFM77711.1 - 0.096 13.0 0.0 0.97 9.8 0.0 2.5 1 1 0 1 1 1 0 PIN like domain F-box PF00646.33 KFM77713.1 - 2.3e-08 33.7 0.5 5e-08 32.6 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFM77713.1 - 0.0014 18.5 0.1 0.0031 17.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like Glucokinase PF02685.16 KFM77713.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Glucokinase Fumble PF03630.14 KFM77715.1 - 1.5e-05 24.4 0.0 1.5e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Fumble Fumble PF03630.14 KFM77716.1 - 1.9e-31 109.5 0.0 2e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Fumble Fumble PF03630.14 KFM77717.1 - 8.3e-26 90.9 0.0 9e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Fumble DUF4615 PF15393.6 KFM77719.1 - 1.9e-27 96.6 5.5 2.1e-27 96.4 5.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4615) DUF2344 PF10105.9 KFM77719.1 - 0.031 14.1 0.9 0.036 13.9 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) PDE4_UCR PF18100.1 KFM77719.1 - 0.21 12.3 5.4 3.7 8.2 0.5 2.3 1 1 1 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) Ras PF00071.22 KFM77725.1 - 5.5e-56 188.6 0.0 6.2e-56 188.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM77725.1 - 2.9e-20 72.7 0.0 3.9e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM77725.1 - 1.4e-10 41.0 0.0 1.7e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM77725.1 - 5e-07 29.4 0.0 1.7e-06 27.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM77725.1 - 2.2e-05 24.5 0.0 2.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFM77725.1 - 0.00013 21.9 2.4 0.00081 19.2 0.1 2.0 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KFM77725.1 - 0.00045 20.1 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase DNase_NucA_NucB PF14040.6 KFM77725.1 - 0.01 16.2 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB Serpin PF00079.20 KFM77726.1 - 1.1e-73 248.7 0.1 1.3e-73 248.5 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) AMP-binding PF00501.28 KFM77727.1 - 8.6e-45 153.1 0.0 1.1e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM77727.1 - 9.5e-05 23.3 0.1 0.00021 22.2 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Dmd PF17587.2 KFM77727.1 - 0.019 15.3 0.1 0.045 14.1 0.1 1.6 1 0 0 1 1 1 0 Discriminator of mRNA degradation AsnC_trans_reg PF01037.21 KFM77727.1 - 0.034 14.1 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain DUF4728 PF15860.5 KFM77730.1 - 0.012 16.3 1.3 0.018 15.7 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4728) AMP-binding PF00501.28 KFM77732.1 - 5.5e-48 163.6 0.0 7.1e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM77732.1 - 4.4e-09 36.1 5.0 9.7e-09 35.0 5.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Rotamase PF00639.21 KFM77733.1 - 2.8e-20 73.1 0.0 3.6e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KFM77733.1 - 2.7e-17 63.4 0.0 3.5e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KFM77733.1 - 3.7e-11 42.9 0.2 7.5e-11 41.9 0.2 1.5 1 0 0 1 1 1 1 WW domain X8 PF07983.13 KFM77733.1 - 0.053 14.2 0.0 0.098 13.4 0.0 1.4 1 0 0 1 1 1 0 X8 domain Rotamase_2 PF13145.6 KFM77733.1 - 0.062 14.1 0.0 0.086 13.7 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain MBD PF01429.19 KFM77733.1 - 0.1 12.3 0.4 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Methyl-CpG binding domain PAS_3 PF08447.12 KFM77734.1 - 0.00052 20.2 0.0 0.00097 19.4 0.0 1.5 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KFM77734.1 - 0.024 14.6 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 PAS fold PAS_11 PF14598.6 KFM77734.1 - 0.036 14.2 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 KFM77735.1 - 3.2e-05 23.9 0.0 3.2e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KFM77735.1 - 0.041 14.2 0.0 0.045 14.0 0.0 1.1 1 0 0 1 1 1 0 PAS fold Cons_hypoth698 PF03601.14 KFM77736.1 - 0.046 12.6 0.2 0.046 12.6 0.2 1.0 1 0 0 1 1 1 0 Conserved hypothetical protein 698 TPR_1 PF00515.28 KFM77737.1 - 4.7e-28 95.8 13.2 9e-07 28.5 0.0 7.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFM77737.1 - 1.1e-20 72.0 12.0 0.00013 21.8 0.0 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFM77737.1 - 3.7e-19 68.8 2.3 3.2e-08 33.8 0.0 4.9 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM77737.1 - 1.9e-18 65.1 5.3 0.00025 20.8 0.0 6.1 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM77737.1 - 1.2e-17 64.2 0.0 1.6e-05 25.5 0.0 4.8 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFM77737.1 - 3.4e-17 61.2 11.5 0.00011 22.2 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 KFM77737.1 - 9e-13 48.0 3.6 0.4 11.4 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM77737.1 - 6.4e-12 45.0 5.4 0.017 14.8 0.0 5.4 6 0 0 6 6 6 3 TPR repeat TPR_19 PF14559.6 KFM77737.1 - 1.7e-10 41.2 8.1 0.022 15.2 0.2 5.9 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_21 PF09976.9 KFM77737.1 - 2.5e-08 33.9 6.5 2.2e-05 24.2 2.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KFM77737.1 - 2.5e-08 33.5 0.2 0.03 14.2 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM77737.1 - 6.6e-08 32.8 0.1 0.66 10.9 0.0 6.0 4 1 2 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM77737.1 - 2.1e-06 27.9 3.4 0.28 11.5 0.3 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KFM77737.1 - 9.3e-06 25.2 0.1 0.0074 15.7 0.0 2.8 2 1 0 2 2 2 2 MalT-like TPR region TPR_3 PF07720.12 KFM77737.1 - 0.00056 19.9 8.9 1.9 8.6 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat HemY_N PF07219.13 KFM77737.1 - 0.00085 19.5 2.3 3.2 8.0 0.1 3.8 3 1 1 4 4 4 2 HemY protein N-terminus TPR_17 PF13431.6 KFM77737.1 - 0.00088 19.5 12.5 3.8 8.1 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat Sel1 PF08238.12 KFM77737.1 - 0.006 17.2 0.2 34 5.3 0.0 3.7 3 0 0 3 3 3 0 Sel1 repeat PPR PF01535.20 KFM77737.1 - 0.016 15.4 0.2 4.7 7.7 0.1 4.1 4 0 0 4 4 4 0 PPR repeat TPR_5 PF12688.7 KFM77737.1 - 0.029 14.6 0.0 8.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Tetratrico peptide repeat MIT PF04212.18 KFM77737.1 - 0.033 14.3 15.4 3.7 7.7 0.0 6.4 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 KFM77737.1 - 0.078 13.1 0.7 25 5.0 0.0 3.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 KFM77737.1 - 0.12 13.0 0.0 2.5 9.0 0.0 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM77738.1 - 9.9e-09 35.3 0.0 0.001 19.7 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM77738.1 - 3e-07 30.1 1.8 0.0083 16.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM77738.1 - 4.1e-07 30.4 0.2 2.1e-06 28.2 0.0 2.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM77738.1 - 0.00039 20.1 1.5 0.048 13.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM77738.1 - 0.00059 20.4 0.2 0.026 15.2 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM77738.1 - 0.0021 18.3 1.0 0.28 11.5 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM77738.1 - 0.0023 17.8 0.8 1.1 9.5 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM77738.1 - 0.0077 16.8 4.4 0.073 13.7 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM77738.1 - 0.012 15.8 1.7 0.014 15.7 0.6 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFM77738.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM77738.1 - 0.012 15.7 5.5 0.13 12.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3591 PF12157.8 KFM77739.1 - 6.8e-152 506.2 0.0 1.2e-151 505.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KFM77739.1 - 5.2e-40 135.4 2.2 2.7e-20 72.2 0.1 2.9 2 0 0 2 2 2 2 Bromodomain UPF0240 PF06784.11 KFM77739.1 - 8.1e-23 81.4 0.4 8.1e-23 81.4 0.4 3.1 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0240) zf-CCHC_6 PF15288.6 KFM77739.1 - 4.5e-14 52.0 0.6 9.8e-14 50.9 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle CpXC PF14353.6 KFM77739.1 - 0.041 13.9 0.2 0.21 11.7 0.2 2.2 1 0 0 1 1 1 0 CpXC protein zf-nanos PF05741.13 KFM77739.1 - 0.058 13.6 0.2 0.15 12.3 0.2 1.7 1 0 0 1 1 1 0 Nanos RNA binding domain Transposase_1 PF01359.18 KFM77740.1 - 2.2e-07 30.6 0.0 2.9e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Transposase (partial DDE domain) SpoIIID PF12116.8 KFM77740.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D PP2C PF00481.21 KFM77742.1 - 1.5e-82 277.1 0.1 2e-82 276.7 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 KFM77742.1 - 1.5e-15 57.4 0.2 1.2e-13 51.3 0.1 2.6 3 0 0 3 3 3 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 KFM77742.1 - 0.0065 16.1 0.0 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Med30 PF11315.8 KFM77743.1 - 0.0034 17.6 3.3 0.0034 17.6 1.5 1.8 2 0 0 2 2 2 1 Mediator complex subunit 30 AAA_13 PF13166.6 KFM77743.1 - 0.0051 15.5 2.8 0.012 14.2 2.8 1.6 1 0 0 1 1 1 1 AAA domain PhoU_div PF01865.16 KFM77743.1 - 0.032 13.6 1.6 0.19 11.0 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF47 UPF0242 PF06785.11 KFM77743.1 - 0.062 13.4 6.6 0.046 13.8 3.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CorA PF01544.18 KFM77743.1 - 0.074 12.3 0.9 0.11 11.8 0.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mod_r PF07200.13 KFM77743.1 - 0.096 12.8 4.0 0.056 13.6 2.2 1.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cep57_CLD_2 PF14197.6 KFM77743.1 - 0.11 12.6 1.2 0.31 11.1 1.2 1.8 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Mer2 PF09074.10 KFM77743.1 - 0.2 11.5 8.1 0.095 12.5 4.9 2.0 2 1 0 2 2 2 0 Mer2 Sec2p PF06428.11 KFM77743.1 - 0.21 11.6 7.9 0.13 12.3 4.5 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Sec8_exocyst PF04048.14 KFM77743.1 - 0.53 10.2 5.4 0.11 12.3 1.2 2.1 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain TPR_MLP1_2 PF07926.12 KFM77743.1 - 0.62 10.1 6.2 0.87 9.7 1.0 2.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 KFM77743.1 - 0.77 10.2 4.4 0.52 10.8 1.1 2.2 1 1 1 2 2 2 0 Cell division protein ZapB HMMR_N PF15905.5 KFM77743.1 - 0.85 9.0 8.2 0.25 10.8 4.1 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 KFM77743.1 - 1.3 9.5 4.9 8.4 6.9 0.3 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin_2 PF14523.6 KFM77743.1 - 1.5 9.2 5.9 3.3 8.1 1.0 2.7 2 1 1 3 3 3 0 Syntaxin-like protein NEMO PF11577.8 KFM77743.1 - 3 7.9 6.1 1 9.4 0.7 2.5 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO DUF4201 PF13870.6 KFM77743.1 - 3.7 7.2 9.7 0.38 10.5 5.5 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4201) FapA PF03961.13 KFM77743.1 - 5 5.6 7.8 0.98 7.9 4.7 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A FAM76 PF16046.5 KFM77743.1 - 9.9 5.4 8.6 3.1 7.1 4.4 2.1 2 1 0 2 2 2 0 FAM76 protein Reticulon PF02453.17 KFM77744.1 - 5.4e-46 156.4 8.2 7.2e-46 156.0 8.2 1.2 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.12 KFM77744.1 - 0.0013 18.1 2.5 0.0022 17.4 2.5 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) GpcrRhopsn4 PF10192.9 KFM77745.1 - 3.9e-19 69.1 1.0 4.5e-19 68.9 1.0 1.0 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain GpcrRhopsn4 PF10192.9 KFM77746.1 - 2.4e-14 53.4 0.4 2.5e-14 53.3 0.4 1.0 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Acetyltransf_1 PF00583.25 KFM77748.1 - 1.4e-15 57.5 0.0 2.4e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM77748.1 - 2.9e-07 30.8 0.0 5.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM77748.1 - 3.5e-07 30.2 0.0 5.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM77748.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFM77748.1 - 0.0034 17.5 0.0 0.0059 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFM77748.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LPD11 PF18824.1 KFM77749.1 - 0.17 12.0 2.0 7.5 6.7 0.2 2.7 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 TFIID_NTD2 PF04494.15 KFM77750.1 - 1.1e-43 148.5 3.2 1.1e-43 148.5 3.2 1.8 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 KFM77750.1 - 3.4e-34 116.3 18.4 2.8e-11 43.8 0.5 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KFM77750.1 - 1.2e-06 27.5 2.2 0.01 14.5 0.0 3.3 2 1 0 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFM77750.1 - 1e-05 25.8 0.0 0.019 15.2 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KFM77750.1 - 0.031 14.2 0.0 0.12 12.4 0.0 2.1 1 0 0 1 1 1 0 LisH DUF1676 PF07898.13 KFM77750.1 - 1 9.4 3.0 0.77 9.8 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) I-set PF07679.16 KFM77751.1 - 3.7e-59 196.8 0.6 2.2e-16 59.7 0.0 5.0 5 1 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM77751.1 - 4.1e-58 193.9 8.3 3.4e-16 59.6 0.2 5.4 5 1 1 6 6 6 4 Immunoglobulin domain ig PF00047.25 KFM77751.1 - 7.4e-45 151.1 6.1 6.3e-11 42.3 0.0 5.6 6 1 0 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 KFM77751.1 - 6.2e-40 135.4 0.1 7e-12 45.5 0.1 4.7 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFM77751.1 - 1e-18 67.5 11.1 0.06 13.5 0.1 8.7 5 5 3 8 8 8 6 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM77751.1 - 2.9e-14 53.2 0.4 0.0016 18.8 0.0 5.0 4 2 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain fn3 PF00041.21 KFM77751.1 - 8.7e-10 38.8 5.0 1.1e-09 38.5 1.4 2.9 3 0 0 3 3 3 1 Fibronectin type III domain Ig_6 PF18452.1 KFM77751.1 - 7.6e-09 35.0 0.0 0.18 11.4 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain Ig_4 PF16680.5 KFM77751.1 - 1.4e-07 31.7 0.0 0.01 16.1 0.0 4.4 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFM77751.1 - 5.5e-07 29.6 0.3 0.38 10.8 0.0 3.8 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFM77751.1 - 7.5e-07 29.1 0.6 0.73 9.9 0.0 4.8 4 2 0 4 4 4 2 C17orf99 Ig domain Izumo-Ig PF16706.5 KFM77751.1 - 7.8e-06 25.9 0.0 6.8 6.8 0.0 4.9 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM77751.1 - 2.5e-05 24.8 4.4 0.00017 22.1 3.1 2.7 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain FAM183 PF14886.6 KFM77751.1 - 0.017 15.8 0.6 0.032 15.0 0.6 1.4 1 0 0 1 1 1 0 FAM183A and FAM183B related Interfer-bind PF09294.10 KFM77751.1 - 0.07 13.5 0.1 0.35 11.2 0.1 2.3 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Peptidase_A17 PF05380.13 KFM77752.1 - 1.3e-56 191.0 0.3 3.6e-56 189.6 0.3 1.8 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1758 PF05585.12 KFM77752.1 - 1.7e-14 53.9 0.6 4.4e-14 52.6 0.6 1.7 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF5641 PF18701.1 KFM77752.1 - 6.8e-10 39.0 0.2 3e-09 36.9 0.2 2.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 KFM77752.1 - 2.9e-07 30.5 1.4 8.8e-07 28.9 1.4 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 KFM77752.1 - 8.3e-06 26.4 0.0 1.9e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 KFM77752.1 - 0.0011 18.5 0.0 0.003 17.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 KFM77752.1 - 0.0018 18.8 0.0 0.0056 17.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease GBP_C PF02841.14 KFM77752.1 - 0.012 15.0 15.3 0.027 13.9 15.3 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF1870 PF08965.10 KFM77752.1 - 0.039 14.0 0.8 0.27 11.3 1.2 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF1870) SCAN PF02023.17 KFM77752.1 - 0.091 12.6 4.2 0.25 11.2 0.1 2.7 2 0 0 2 2 2 0 SCAN domain Apolipoprotein PF01442.18 KFM77752.1 - 0.12 12.3 11.2 0.22 11.4 11.2 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1640 PF07798.11 KFM77752.1 - 1.7 8.6 11.1 4.4 7.3 11.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) YabA PF06156.13 KFM77752.1 - 1.9 9.1 7.9 1.7 9.4 4.9 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Histone_HNS PF00816.21 KFM77752.1 - 4.3 8.2 6.2 14 6.6 6.2 1.9 1 0 0 1 1 1 0 H-NS histone family DUF1664 PF07889.12 KFM77752.1 - 8.8 6.4 10.5 1.1e+02 2.9 10.0 2.7 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 KFM77753.1 - 1.1e-07 31.5 0.0 1.2e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM77753.1 - 6.8e-06 25.5 0.0 6.9e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_head PF00063.21 KFM77754.1 - 1.9e-24 85.9 0.2 2.1e-24 85.8 0.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AIG1 PF04548.16 KFM77754.1 - 0.012 15.0 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.6 KFM77754.1 - 0.04 14.2 0.0 0.067 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFM77754.1 - 0.062 13.7 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KFM77754.1 - 0.097 12.6 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KFM77754.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM77754.1 - 0.14 12.3 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain PCI PF01399.27 KFM77757.1 - 2.6e-12 47.2 0.0 1e-11 45.3 0.0 2.1 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KFM77757.1 - 0.00069 19.2 0.8 0.0018 17.9 0.8 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix DUF5344 PF17279.2 KFM77757.1 - 0.069 13.7 0.1 1.9 9.1 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Vps39_1 PF10366.9 KFM77757.1 - 1.2 9.5 5.7 0.45 10.8 1.0 2.7 3 1 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 DUF4298 PF14131.6 KFM77757.1 - 2.8 8.0 6.9 6.2 6.8 0.3 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4298) Actin PF00022.19 KFM77758.1 - 2.3e-115 385.5 0.0 1.9e-114 382.4 0.0 1.9 1 1 0 1 1 1 1 Actin DrrA_P4M PF14860.6 KFM77759.1 - 1.7 8.5 6.6 0.96 9.3 3.2 2.2 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain PH PF00169.29 KFM77761.1 - 0.034 14.6 0.2 0.054 14.0 0.2 1.6 1 1 0 1 1 1 0 PH domain RVT_thumb PF06817.14 KFM77762.1 - 0.00039 20.2 0.1 0.00078 19.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain WD40 PF00400.32 KFM77762.1 - 0.008 17.0 0.0 5.9 7.9 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.32 KFM77763.1 - 2.7e-31 107.1 12.7 2.7e-09 37.5 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM77763.1 - 6.3e-13 48.8 0.1 4.9e-06 26.8 0.0 3.2 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM77763.1 - 0.00016 20.8 0.5 0.2 10.6 0.0 3.2 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFM77763.1 - 0.00023 20.6 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain Frtz PF11768.8 KFM77763.1 - 0.023 13.0 0.1 0.12 10.6 0.0 1.9 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KFM77763.1 - 0.29 9.7 1.5 1.4 7.5 0.0 2.6 2 2 2 4 4 4 0 Nucleoporin Nup120/160 WD40 PF00400.32 KFM77764.1 - 1.5e-11 44.7 0.9 3.6e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat MRP_L53 PF10780.9 KFM77767.1 - 2.1e-13 50.2 0.3 7.9e-13 48.4 0.4 1.8 2 0 0 2 2 2 1 39S ribosomal protein L53/MRP-L53 CBM_14 PF01607.24 KFM77769.1 - 4.5e-09 36.3 6.1 7.4e-09 35.6 6.1 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Rtf2 PF04641.12 KFM77770.1 - 4.1e-86 288.6 18.8 9.8e-86 287.4 18.8 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KFM77770.1 - 0.002 18.2 0.3 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein PEPCK_N PF17297.2 KFM77770.1 - 0.022 14.3 0.2 0.05 13.2 0.1 1.7 1 1 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain OCIA PF07051.11 KFM77771.1 - 5.9e-28 96.7 0.0 8.9e-28 96.2 0.0 1.3 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) SUIM_assoc PF16619.5 KFM77771.1 - 0.017 15.2 2.9 0.028 14.5 2.0 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 UPF0489 PF12640.7 KFM77772.1 - 1e-30 107.3 0.8 1.2e-30 107.1 0.8 1.0 1 0 0 1 1 1 1 UPF0489 domain zf-H2C2_5 PF13909.6 KFM77775.1 - 0.0079 15.9 8.2 0.0093 15.7 1.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM77775.1 - 0.013 16.3 1.2 0.013 16.3 1.2 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM77775.1 - 0.05 14.1 0.5 0.05 14.1 0.5 2.7 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 KFM77775.1 - 0.05 13.9 1.3 0.05 13.9 1.3 1.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AT_hook PF02178.19 KFM77776.1 - 0.0086 15.8 1.1 0.015 15.1 0.3 1.9 2 0 0 2 2 2 1 AT hook motif Snf7 PF03357.21 KFM77777.1 - 5e-49 166.2 16.0 5e-49 166.2 16.0 1.4 2 0 0 2 2 2 1 Snf7 SYF2 PF08231.12 KFM77777.1 - 0.069 13.6 9.3 0.088 13.2 9.3 1.3 1 1 0 1 1 1 0 SYF2 splicing factor HAT_KAT11 PF08214.11 KFM77777.1 - 0.86 8.8 4.3 1.3 8.2 4.3 1.3 1 0 0 1 1 1 0 Histone acetylation protein V_ATPase_I PF01496.19 KFM77777.1 - 2.6 5.9 9.0 3.2 5.5 9.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CPSase_L_D3 PF02787.19 KFM77777.1 - 5.3 7.4 7.0 54 4.2 7.0 2.3 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SpoU_sub_bind PF08032.12 KFM77777.1 - 7.7 6.9 8.1 1.7 9.0 3.2 2.2 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding JmjC PF02373.22 KFM77778.1 - 3.7e-44 149.8 0.7 3.7e-44 149.8 0.7 2.9 3 0 0 3 3 3 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KFM77778.1 - 1.9e-27 95.6 9.3 1.9e-27 95.6 9.3 2.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain Tudor_2 PF18104.1 KFM77778.1 - 2.2e-23 81.6 3.9 3.8e-12 45.7 0.2 2.6 2 0 0 2 2 2 2 Jumonji domain-containing protein 2A Tudor domain JmjN PF02375.17 KFM77778.1 - 3.1e-15 55.8 0.1 7.5e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 KFM77778.1 - 4.5e-14 52.5 7.0 4.5e-14 52.5 7.0 3.6 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFM77778.1 - 8.7e-11 41.2 5.5 8.7e-11 41.2 5.5 3.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KFM77778.1 - 3.1e-05 23.8 2.2 3.1e-05 23.8 2.2 3.5 2 0 0 2 2 2 1 PHD-finger DUF4537 PF15057.6 KFM77778.1 - 0.014 15.4 0.3 0.045 13.8 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) TUDOR_5 PF18359.1 KFM77778.1 - 0.14 11.9 0.6 11 5.8 0.1 2.9 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 zf-C2H2 PF00096.26 KFM77779.1 - 6.2e-26 89.4 32.3 1.2e-06 28.6 0.3 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM77779.1 - 1.7e-19 69.3 35.1 1e-09 38.4 0.2 6.4 6 1 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM77779.1 - 1.9e-19 68.7 34.9 0.00011 22.7 0.3 6.0 5 1 1 6 6 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM77779.1 - 4.2e-08 33.3 18.7 0.0017 18.5 0.0 5.3 6 0 0 6 6 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM77779.1 - 1.5e-06 28.0 24.6 0.00035 20.5 2.0 5.6 5 0 0 5 5 5 2 C2H2-type zinc finger zf-Di19 PF05605.12 KFM77779.1 - 2.4e-06 27.8 22.5 0.00045 20.4 2.1 4.2 1 1 2 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFM77779.1 - 0.0012 18.6 22.8 0.057 13.2 2.1 4.8 5 0 0 5 5 5 2 zinc-finger C2H2-type zf_UBZ PF18439.1 KFM77779.1 - 0.0029 17.2 17.1 0.46 10.1 0.1 5.5 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFM77779.1 - 0.0036 17.6 0.1 0.0036 17.6 0.1 5.6 7 0 0 7 7 6 2 Zinc-finger of C2H2 type GAGA PF09237.11 KFM77779.1 - 0.0075 16.1 0.2 0.0075 16.1 0.2 3.5 2 1 0 4 4 4 1 GAGA factor zf-piccolo PF05715.13 KFM77779.1 - 0.036 14.2 1.2 0.036 14.2 1.2 3.5 2 1 0 3 3 2 0 Piccolo Zn-finger Zn-C2H2_12 PF18112.1 KFM77779.1 - 0.051 14.0 15.5 0.64 10.5 0.0 5.0 4 1 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_15 PF17032.5 KFM77779.1 - 0.072 13.8 0.9 0.072 13.8 0.9 3.4 2 2 0 2 2 2 0 zinc-ribbon family ROS_MUCR PF05443.11 KFM77779.1 - 0.089 12.8 1.3 0.51 10.4 0.2 2.5 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein zinc_ribbon_9 PF14369.6 KFM77779.1 - 0.21 11.9 21.1 12 6.3 0.1 5.9 6 0 0 6 6 5 0 zinc-ribbon zf_C2H2_13 PF18508.1 KFM77779.1 - 0.39 10.3 4.0 4 7.1 0.1 3.1 3 0 0 3 3 3 0 Zinc finger domain Zn-ribbon_8 PF09723.10 KFM77779.1 - 0.52 10.5 22.4 0.91 9.7 1.7 4.4 4 2 0 4 4 4 0 Zinc ribbon domain HypA PF01155.19 KFM77779.1 - 0.94 9.5 17.7 0.54 10.3 1.3 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 KFM77779.1 - 1.1 9.3 27.4 2.9 8.0 0.1 5.4 1 1 4 5 5 5 0 BED zinc finger FYVE PF01363.21 KFM77779.1 - 1.3 9.2 24.7 2.7 8.2 3.3 3.4 1 1 3 4 4 4 0 FYVE zinc finger FYDLN_acid PF09538.10 KFM77779.1 - 7.7 7.2 20.0 1.2 9.8 0.2 4.9 3 2 2 5 5 4 0 Protein of unknown function (FYDLN_acid) Complex1_49kDa PF00346.19 KFM77781.1 - 0.081 12.0 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF3310 PF11753.8 KFM77782.1 - 0.006 16.8 0.1 0.013 15.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknwon function (DUF3310) Membralin PF09746.9 KFM77783.1 - 8.3e-133 443.1 14.6 1.2e-132 442.6 14.6 1.2 1 0 0 1 1 1 1 Tumour-associated protein DUF1180 PF06679.12 KFM77783.1 - 0.017 15.5 0.8 0.033 14.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Methyltr_RsmB-F PF01189.17 KFM77784.1 - 4.4e-54 183.2 0.0 5.1e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NAD_binding_10 PF13460.6 KFM77784.1 - 0.057 13.3 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 NAD(P)H-binding CD36 PF01130.21 KFM77785.1 - 2.7e-150 501.0 3.7 3.2e-150 500.7 3.7 1.0 1 0 0 1 1 1 1 CD36 family DDE_1 PF03184.19 KFM77786.1 - 6.3e-42 143.2 0.2 3.1e-41 140.9 0.1 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM77786.1 - 5.2e-15 55.2 0.4 2.1e-14 53.3 0.3 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM77786.1 - 2.8e-05 23.6 5.1 3.3e-05 23.4 2.7 2.4 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KFM77786.1 - 0.013 15.2 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.16 KFM77786.1 - 0.022 14.5 0.1 0.1 12.4 0.0 2.1 3 0 0 3 3 3 0 helix-turn-helix, Psq domain Ada3 PF10198.9 KFM77786.1 - 0.12 12.5 0.9 0.28 11.3 0.3 1.9 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 Peptidase_M16 PF00675.20 KFM77787.1 - 1.1e-29 103.4 0.0 1.8e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFM77787.1 - 7.9e-17 61.9 0.0 1.5e-16 60.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 KFM77787.1 - 0.015 14.6 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 rpo30_N PF12410.8 KFM77787.1 - 0.16 11.9 0.0 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit Lactamase_B_2 PF12706.7 KFM77789.1 - 6.1e-33 114.0 0.0 7.8e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFM77789.1 - 1.7e-11 44.3 0.1 2.5e-11 43.7 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFM77789.1 - 0.71 9.8 7.1 1.3 9.0 4.7 2.4 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF3912 PF13051.6 KFM77790.1 - 0.15 12.3 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) C5-epim_C PF06662.13 KFM77791.1 - 7.5e-71 237.5 0.1 1.2e-70 236.8 0.1 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus Prenyltrans PF00432.21 KFM77791.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat DDE_1 PF03184.19 KFM77792.1 - 5.3e-35 120.6 0.9 7.3e-35 120.2 0.3 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM77792.1 - 2.9e-12 46.4 0.3 8.2e-12 45.0 0.2 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFM77792.1 - 1.9e-06 27.4 0.6 6.4e-06 25.7 0.6 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DDE_3 PF13358.6 KFM77792.1 - 0.0095 15.7 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 KFM77792.1 - 0.014 15.2 0.1 0.094 12.5 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Nuf2 PF03800.14 KFM77792.1 - 0.12 12.5 0.9 1.5 8.9 0.3 2.4 2 0 0 2 2 2 0 Nuf2 family Focal_AT PF03623.13 KFM77792.1 - 4.7 7.2 8.4 3.5 7.6 4.2 2.3 2 0 0 2 2 2 0 Focal adhesion targeting region FXa_inhibition PF14670.6 KFM77793.1 - 1.9e-46 156.0 143.8 7.6e-11 42.1 11.6 35.1 11 2 15 27 27 27 8 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFM77793.1 - 2e-28 97.9 52.9 1.8e-08 34.2 1.8 35.4 33 6 2 35 35 35 10 Complement Clr-like EGF-like Laminin_EGF PF00053.24 KFM77793.1 - 3.5e-24 84.7 565.8 0.0048 17.0 14.9 30.7 3 2 27 30 30 30 17 Laminin EGF domain EGF_CA PF07645.15 KFM77793.1 - 6.6e-19 67.8 62.9 4.3e-07 30.0 8.7 31.4 21 6 9 30 30 30 6 Calcium-binding EGF domain hEGF PF12661.7 KFM77793.1 - 1e-05 26.0 48.5 0.0005 20.6 5.3 39.7 37 7 4 41 41 41 14 Human growth factor-like EGF EGF_3 PF12947.7 KFM77793.1 - 0.00021 21.4 6.7 0.00021 21.4 6.7 30.9 29 6 2 31 31 31 7 EGF domain EGF PF00008.27 KFM77793.1 - 0.00068 19.9 27.4 0.0019 18.5 5.3 37.5 34 5 2 36 36 36 18 EGF-like domain EGF_2 PF07974.13 KFM77793.1 - 0.0022 18.3 57.3 0.0067 16.8 12.5 44.3 34 14 6 40 40 40 11 EGF-like domain HCO3_cotransp PF00955.21 KFM77796.1 - 1e-25 90.6 5.8 1.1e-25 90.5 5.8 1.0 1 0 0 1 1 1 1 HCO3- transporter family HCO3_cotransp PF00955.21 KFM77797.1 - 1.8e-16 60.1 0.0 2.1e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 HCO3- transporter family LrgB PF04172.16 KFM77797.1 - 0.084 12.4 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 LrgB-like family HCO3_cotransp PF00955.21 KFM77798.1 - 3.1e-26 92.3 0.5 3.1e-26 92.3 0.5 1.3 2 0 0 2 2 2 1 HCO3- transporter family SUZ PF12752.7 KFM77800.1 - 4.9e-14 52.8 10.6 4.9e-14 52.8 10.6 4.7 5 0 0 5 5 5 1 SUZ domain R3H PF01424.22 KFM77800.1 - 4.3e-13 49.0 0.0 1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain DUF2584 PF10763.9 KFM77800.1 - 0.1 12.7 0.2 0.28 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2584) DUF4834 PF16118.5 KFM77800.1 - 10 7.2 8.4 1.3 10.1 1.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RGS PF00615.19 KFM77801.1 - 1.5e-14 54.2 0.1 3.2e-14 53.2 0.0 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain Sushi PF00084.20 KFM77803.1 - 3.8e-19 69.0 5.4 1.2e-10 41.8 0.2 2.7 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) CUB PF00431.20 KFM77803.1 - 4e-11 43.2 0.1 1.7e-08 34.7 0.1 2.4 2 0 0 2 2 2 2 CUB domain SKG6 PF08693.10 KFM77803.1 - 0.0016 17.8 10.1 0.0036 16.7 10.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MFS_1 PF07690.16 KFM77805.1 - 1.7e-11 43.7 5.1 1.8e-11 43.6 5.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM77805.1 - 3.8e-11 42.5 2.5 4.6e-11 42.2 2.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Gate PF07670.14 KFM77805.1 - 0.0076 16.5 0.8 0.014 15.7 0.4 1.6 1 1 0 1 1 1 1 Nucleoside recognition DUF1440 PF07274.12 KFM77805.1 - 0.039 14.3 0.2 0.83 10.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) OATP PF03137.20 KFM77806.1 - 5e-130 434.4 16.6 6e-130 434.1 16.6 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFM77806.1 - 1.4e-17 63.7 29.8 1.4e-17 63.7 29.8 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFM77806.1 - 5.4e-06 26.4 9.2 1.3e-05 25.2 9.2 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM77806.1 - 0.091 12.8 5.9 0.24 11.4 5.9 1.7 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain OATP PF03137.20 KFM77807.1 - 1.1e-16 60.3 0.9 2e-16 59.4 0.2 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_LBD PF02931.23 KFM77808.1 - 4.6e-11 42.6 0.0 5.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM77808.1 - 2.4e-05 24.5 0.9 3.3e-05 24.1 0.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4733 PF15878.5 KFM77808.1 - 0.014 15.8 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4733) DDE_Tnp_1_7 PF13843.6 KFM77809.1 - 3e-97 326.1 0.0 3.7e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Sec61_beta PF03911.16 KFM77810.1 - 2.4e-20 72.2 0.0 3.2e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Sec61beta family Tropomodulin PF03250.14 KFM77811.1 - 2.2e-51 173.6 4.8 2.2e-51 173.6 4.8 1.7 2 0 0 2 2 2 1 Tropomodulin FumaraseC_C PF10415.9 KFM77811.1 - 0.036 14.5 0.2 0.13 12.8 0.0 2.1 2 0 0 2 2 2 0 Fumarase C C-terminus MgtE_N PF03448.17 KFM77811.1 - 0.04 14.5 2.8 0.44 11.2 1.0 3.0 2 0 0 2 2 2 0 MgtE intracellular N domain Pericardin_rpt PF07054.11 KFM77812.1 - 0.00033 20.7 0.1 2.5 8.3 0.1 3.3 1 1 2 3 3 3 3 Pericardin like repeat Keratin_2_head PF16208.5 KFM77812.1 - 2.1 8.4 18.8 4.7 7.3 18.8 1.5 1 1 0 1 1 1 0 Keratin type II head SGP PF17228.2 KFM77812.1 - 3.9 8.4 12.3 22 6.0 12.3 2.0 1 1 0 1 1 1 0 Sulphur globule protein Popeye PF04831.13 KFM77813.1 - 1.5e-49 167.8 2.9 1.9e-49 167.4 2.9 1.1 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 KFM77813.1 - 7e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DDE_3 PF13358.6 KFM77814.1 - 0.00065 19.5 0.4 0.0033 17.2 0.1 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease DUF859 PF05895.12 KFM77814.1 - 0.019 13.5 0.0 0.023 13.2 0.0 1.0 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) HTH_36 PF13730.6 KFM77814.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KFM77814.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain PAE PF03283.13 KFM77815.1 - 0.0092 15.1 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Pectinacetylesterase Peptidase_S49_N PF08496.10 KFM77815.1 - 2.7 8.0 6.8 4.8 7.2 6.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec1 PF00995.23 KFM77819.1 - 1.4e-63 216.1 0.1 1.5e-63 215.9 0.1 1.0 1 0 0 1 1 1 1 Sec1 family CNOT1_HEAT PF16418.5 KFM77819.1 - 0.13 12.3 0.0 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Cyclase PF04199.13 KFM77820.1 - 8.8e-33 113.4 0.0 1.4e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase RRM_1 PF00076.22 KFM77821.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KFM77822.1 - 4.6e-40 138.3 0.1 5.7e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFM77822.1 - 1.3e-22 79.9 0.5 3.1e-22 78.8 0.5 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PDZ PF00595.24 KFM77824.1 - 8.9e-09 35.6 0.0 2.8e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM77824.1 - 6.2e-07 29.2 0.0 9.2e-05 22.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Laminin_G_2 PF02210.24 KFM77826.1 - 5.9e-12 46.3 0.3 1.2e-11 45.3 0.3 1.5 1 0 0 1 1 1 1 Laminin G domain Syndecan PF01034.20 KFM77826.1 - 1.4e-11 44.1 0.2 2.9e-11 43.1 0.2 1.4 1 0 0 1 1 1 1 Syndecan domain Laminin_G_1 PF00054.23 KFM77826.1 - 0.002 18.3 0.1 0.0038 17.4 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain Glycophorin_A PF01102.18 KFM77826.1 - 0.0051 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Glycophorin A Podoplanin PF05808.11 KFM77826.1 - 0.015 15.4 0.1 0.059 13.5 0.0 2.1 2 0 0 2 2 2 0 Podoplanin Protocadherin PF08374.11 KFM77826.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Protocadherin DUF4690 PF15756.5 KFM77826.1 - 0.036 14.7 0.1 0.036 14.7 0.1 2.2 2 1 0 2 2 2 0 Small Novel Rich in Cartilage DUF5305 PF17231.2 KFM77826.1 - 0.053 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) MtrF PF09472.10 KFM77826.1 - 0.12 11.8 0.5 0.25 10.8 0.5 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3827 PF12877.7 KFM77826.1 - 0.17 10.2 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Exo_endo_phos PF03372.23 KFM77827.1 - 0.00016 21.2 0.0 0.00019 21.1 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-H2C2_2 PF13465.6 KFM77828.1 - 2.7e-08 33.9 7.7 2.9e-07 30.6 0.1 3.0 3 1 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM77828.1 - 6.1e-05 22.7 2.1 6.1e-05 22.7 2.1 2.5 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM77828.1 - 0.00018 21.8 1.6 0.00018 21.8 1.6 2.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM77828.1 - 0.00055 20.6 14.8 0.0013 19.4 1.8 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM77828.1 - 0.0054 16.5 0.4 0.0054 16.5 0.4 2.6 2 1 0 2 2 2 1 zinc-finger C2H2-type GAGA PF09237.11 KFM77828.1 - 0.011 15.5 3.0 0.19 11.5 0.1 2.4 2 1 1 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.7 KFM77828.1 - 0.015 15.6 4.6 0.86 10.0 0.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SURF2 PF05477.11 KFM77828.1 - 0.047 13.4 1.9 0.048 13.4 1.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ARS2 PF04959.13 KFM77828.1 - 0.067 13.6 1.3 0.076 13.4 1.3 1.1 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Actin_micro PF17003.5 KFM77828.1 - 0.078 12.2 3.9 0.24 10.6 1.3 1.9 1 1 1 2 2 2 0 Putative actin-like family zf-C2H2_9 PF16293.5 KFM77828.1 - 0.091 12.6 0.2 1 9.3 0.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 KFM77828.1 - 0.15 12.7 4.2 0.82 10.4 3.9 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn_ribbon_SprT PF17283.2 KFM77828.1 - 0.25 11.3 5.8 0.39 10.7 5.8 1.3 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-H2C2_2 PF13465.6 KFM77829.1 - 4e-10 39.6 7.1 3.7e-09 36.6 1.7 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM77829.1 - 2e-05 24.8 14.0 0.0027 18.1 0.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM77829.1 - 0.0015 19.2 10.8 0.23 12.4 0.4 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger IBR PF01485.21 KFM77829.1 - 0.017 15.4 0.9 0.02 15.1 0.9 1.1 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 KFM77829.1 - 0.059 13.7 3.1 0.059 13.7 3.1 3.0 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RecR PF02132.15 KFM77829.1 - 0.07 12.7 4.2 0.76 9.4 4.2 2.2 1 1 0 1 1 1 0 RecR protein zn-ribbon_14 PF16503.5 KFM77829.1 - 1.5 8.4 4.4 14 5.3 0.5 2.2 2 0 0 2 2 2 0 Zinc-ribbon zf-H2C2_5 PF13909.6 KFM77829.1 - 2.1 8.2 10.2 0.14 11.9 2.8 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFM77832.1 - 1.2e-08 34.9 1.5 1.2e-08 34.9 1.5 1.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFM77832.1 - 0.00014 22.2 16.3 0.00059 20.1 6.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM77832.1 - 0.0063 16.8 0.3 0.0063 16.8 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFM77832.1 - 0.012 16.4 12.3 0.022 15.6 4.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KFM77832.1 - 0.016 15.6 4.4 0.016 15.6 4.4 2.3 1 1 1 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM77832.1 - 0.018 14.8 0.9 0.018 14.8 0.9 2.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM77832.1 - 0.021 14.8 1.6 0.021 14.8 1.6 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger RRM_1 PF00076.22 KFM77833.1 - 1.3e-26 92.2 0.0 5.4e-11 42.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM77833.1 - 0.011 15.8 0.2 3.4 7.8 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif SplA PF11132.8 KFM77834.1 - 0.19 11.5 1.0 0.56 10.0 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator protein (SplA) Atx10homo_assoc PF09759.9 KFM77834.1 - 4.1 7.5 7.4 0.82 9.7 0.8 2.7 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain PAH PF02671.21 KFM77835.1 - 6.5e-09 35.8 3.3 9.5e-05 22.5 0.1 2.7 2 0 0 2 2 2 2 Paired amphipathic helix repeat Eclosion PF04736.12 KFM77838.1 - 2.7e-22 78.2 0.9 2.8e-22 78.2 0.9 1.1 1 0 0 1 1 1 1 Eclosion hormone An_peroxidase PF03098.15 KFM77839.1 - 3.8e-41 141.2 0.1 4.9e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 KFM77840.1 - 4.4e-130 434.7 0.0 5.5e-130 434.4 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase DDE_1 PF03184.19 KFM77841.1 - 3.4e-50 170.1 0.1 6.2e-50 169.3 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFM77841.1 - 2.4e-12 46.7 0.1 1.9e-11 43.8 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain TPR_15 PF13429.6 KFM77842.1 - 0.0069 15.6 0.0 0.028 13.6 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM77842.1 - 0.018 15.9 0.0 1.7e+02 3.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFM77842.1 - 0.058 14.0 0.0 77 4.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Spond_N PF06468.13 KFM77843.1 - 4e-79 265.2 0.1 5.8e-79 264.7 0.1 1.2 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 KFM77843.1 - 2.9e-44 149.1 44.4 7.1e-14 51.8 7.5 5.2 4 1 0 4 4 4 4 Thrombospondin type 1 domain Kunitz_BPTI PF00014.23 KFM77843.1 - 9.6e-17 61.0 8.8 9.6e-17 61.0 8.8 2.4 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Reeler PF02014.16 KFM77843.1 - 6.3e-14 52.8 0.0 1.4e-13 51.8 0.0 1.6 1 0 0 1 1 1 1 Reeler domain DUF483 PF04467.12 KFM77843.1 - 0.018 15.0 0.5 7.5 6.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF483) SNAD4 PF18750.1 KFM77843.1 - 0.052 13.7 0.1 0.052 13.7 0.1 3.2 3 1 1 4 4 4 0 Secreted Novel AID/APOBEC-like Deaminase 4 Pox_F17 PF04767.12 KFM77843.1 - 0.58 10.7 5.4 0.82 10.2 0.8 3.0 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein BTB PF00651.31 KFM77845.1 - 1.6e-39 134.6 6.9 5.2e-26 91.1 0.4 3.1 3 0 0 3 3 3 2 BTB/POZ domain MATH PF00917.26 KFM77845.1 - 1.2e-05 25.4 0.8 4e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 MATH domain BACK PF07707.15 KFM77845.1 - 1.9e-05 24.7 0.1 0.012 15.7 0.0 2.9 2 0 0 2 2 2 2 BTB And C-terminal Kelch BTB_2 PF02214.22 KFM77845.1 - 0.0055 17.0 0.3 3.3 8.1 0.1 2.8 2 0 0 2 2 2 2 BTB/POZ domain PDZ PF00595.24 KFM77847.1 - 1.6e-22 79.6 1.1 6.5e-13 48.9 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM77847.1 - 3.1e-16 59.0 1.5 9.2e-08 31.8 0.5 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFM77847.1 - 2.8e-08 33.9 3.1 0.0031 17.8 0.1 2.9 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 KFM77849.1 - 1e-18 67.4 0.2 2.4e-09 37.4 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM77849.1 - 1.4e-13 50.5 0.4 7.7e-07 28.9 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFM77849.1 - 4.5e-05 23.7 0.1 0.18 12.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_4 PF17816.1 KFM77849.1 - 0.011 16.1 0.0 2 8.8 0.0 2.3 2 0 0 2 2 2 0 PDZ domain LptD PF04453.14 KFM77849.1 - 0.25 10.5 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 LPS transport system D Corona_M PF01635.18 KFM77850.1 - 0.011 15.0 1.7 0.019 14.3 1.7 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein AmiS_UreI PF02293.15 KFM77850.1 - 0.018 15.0 4.4 0.02 14.9 4.4 1.2 1 0 0 1 1 1 0 AmiS/UreI family transporter CDP-OH_P_transf PF01066.21 KFM77851.1 - 3.3e-16 59.8 0.2 3.3e-16 59.8 0.2 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PsbH PF00737.20 KFM77851.1 - 0.86 9.4 5.8 0.29 10.9 1.3 2.3 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein SERTA PF06031.13 KFM77852.1 - 8.4e-14 51.0 0.2 1.5e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 SERTA motif Sulfatase PF00884.23 KFM77853.1 - 3e-19 69.6 0.0 3.7e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 KFM77853.1 - 0.0027 16.8 0.1 0.0033 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) PAN_4 PF14295.6 KFM77854.1 - 0.00021 21.1 0.2 0.00021 21.1 0.2 1.6 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 KFM77854.1 - 0.00073 19.5 2.7 0.00081 19.3 2.7 1.3 1 1 0 1 1 1 1 PAN domain PAN_2 PF08276.11 KFM77854.1 - 0.0048 17.0 1.0 0.0059 16.7 1.0 1.3 1 1 0 1 1 1 1 PAN-like domain PAN_3 PF08277.12 KFM77854.1 - 2.4 8.1 6.6 0.56 10.1 2.5 2.0 1 1 1 2 2 2 0 PAN-like domain PAN_1 PF00024.26 KFM77855.1 - 2.5e-10 40.2 4.2 2.9e-10 40.0 4.2 1.1 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KFM77856.1 - 0.00043 20.2 0.0 0.00043 20.2 0.0 1.1 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KFM77856.1 - 0.0019 18.1 0.1 0.0021 18.0 0.1 1.2 1 0 0 1 1 1 1 PAN domain LRR_8 PF13855.6 KFM77857.1 - 4.5e-39 132.0 39.1 5.5e-11 42.1 4.5 7.5 3 2 7 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 KFM77857.1 - 3.1e-18 65.6 50.1 0.0022 18.3 0.3 8.9 5 3 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM77857.1 - 7.1e-16 58.3 25.3 3.2e-06 27.1 0.0 5.5 3 2 2 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM77857.1 - 3.9e-08 33.0 19.7 0.00015 21.3 0.4 4.3 1 1 4 5 5 5 3 Leucine-rich repeat Haem_oxygenas_2 PF14518.6 KFM77857.1 - 0.041 13.6 0.1 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 Iron-containing redox enzyme Glyco_hydro_31 PF01055.26 KFM77857.1 - 0.72 9.0 5.7 6.5 5.8 1.6 2.2 1 1 1 2 2 2 0 Glycosyl hydrolases family 31 LRR_1 PF00560.33 KFM77857.1 - 3.6 8.5 42.4 13 6.8 0.0 11.9 14 1 0 14 14 14 0 Leucine Rich Repeat TIR PF01582.20 KFM77858.1 - 2.4e-18 66.5 0.1 3.2e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFM77858.1 - 2.7e-13 50.5 0.0 4.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 TIR domain DUF2207 PF09972.9 KFM77858.1 - 0.068 11.9 0.5 0.089 11.5 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.24 KFM77858.1 - 0.077 12.8 0.4 0.093 12.6 0.4 1.1 1 0 0 1 1 1 0 Fatty acid desaturase LRR_8 PF13855.6 KFM77859.1 - 2.2e-38 129.8 41.7 5.5e-11 42.1 4.5 7.6 4 2 7 11 11 11 9 Leucine rich repeat LRR_5 PF13306.6 KFM77859.1 - 4.2e-17 62.3 22.5 3.1e-06 27.1 0.0 5.4 3 2 2 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM77859.1 - 6e-17 61.5 55.7 0.0022 18.4 0.3 9.4 7 3 2 10 10 10 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM77859.1 - 4.4e-08 32.8 19.9 0.00015 21.3 0.4 4.3 1 1 4 5 5 5 3 Leucine-rich repeat Haem_oxygenas_2 PF14518.6 KFM77859.1 - 0.042 13.6 0.1 0.089 12.6 0.1 1.4 1 0 0 1 1 1 0 Iron-containing redox enzyme LRR_1 PF00560.33 KFM77859.1 - 0.13 12.9 38.8 13 6.8 0.0 12.1 14 1 0 14 14 14 0 Leucine Rich Repeat TIR PF01582.20 KFM77860.1 - 3.1e-23 82.5 0.1 4.2e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFM77860.1 - 6.5e-16 59.0 0.1 1e-15 58.4 0.1 1.3 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 KFM77860.1 - 0.05 13.9 0.1 0.13 12.6 0.1 1.7 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) DUF2207 PF09972.9 KFM77860.1 - 0.093 11.5 0.3 0.13 11.0 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PAS PF00989.25 KFM77862.1 - 5e-09 36.1 0.0 8.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 PAS fold HLH PF00010.26 KFM77862.1 - 1.4e-06 28.2 0.4 1.4e-06 28.2 0.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_3 PF08447.12 KFM77862.1 - 0.00045 20.5 0.2 0.00083 19.6 0.2 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KFM77862.1 - 0.0055 16.8 0.2 0.013 15.6 0.2 1.6 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 KFM77862.1 - 0.034 14.4 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 PAS domain DUF659 PF04937.15 KFM77863.1 - 0.0041 17.0 0.5 0.0099 15.7 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DUF4371 PF14291.6 KFM77863.1 - 0.0081 15.8 0.1 0.048 13.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFM77863.1 - 0.017 14.9 0.1 0.26 11.1 0.1 2.8 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region PH PF00169.29 KFM77864.1 - 0.19 12.2 0.0 0.25 11.9 0.0 1.2 1 0 0 1 1 1 0 PH domain CC190 PF15768.5 KFM77865.1 - 0.05 13.7 2.5 0.058 13.5 2.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 MRP-L28 PF09812.9 KFM77867.1 - 1.3e-21 77.4 0.5 1.6e-21 77.1 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Tnp_P_element PF12017.8 KFM77868.1 - 1.7e-37 129.0 0.4 1.7e-37 129.0 0.4 1.6 2 0 0 2 2 2 1 Transposase protein GFRP PF06399.13 KFM77868.1 - 0.0051 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) Methyltrn_RNA_2 PF04013.12 KFM77868.1 - 0.1 12.3 0.1 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Putative SAM-dependent RNA methyltransferase Ig_3 PF13927.6 KFM77870.1 - 2.5e-32 111.3 3.0 5.4e-13 49.3 1.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM77870.1 - 4e-23 81.3 0.4 2.9e-08 33.7 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM77870.1 - 2.4e-22 79.0 1.1 3.5e-09 36.9 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 KFM77870.1 - 2e-15 56.7 0.4 2.3e-06 27.7 0.0 3.3 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFM77870.1 - 6.1e-10 39.3 4.1 0.19 11.9 0.0 5.1 3 2 2 5 5 5 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM77870.1 - 0.00018 21.0 2.3 0.0014 18.2 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.5 KFM77870.1 - 0.0003 21.0 0.0 0.47 10.7 0.0 2.6 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFM77870.1 - 0.0019 18.3 0.2 0.7 10.0 0.0 3.3 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM77870.1 - 0.0066 16.8 0.0 0.071 13.5 0.0 2.4 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Syndecan PF01034.20 KFM77870.1 - 0.013 15.4 4.6 0.034 14.0 4.6 1.6 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR1 PF02440.15 KFM77870.1 - 0.015 15.0 1.5 8.7 6.2 0.0 3.1 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 SNF2_N PF00176.23 KFM77871.1 - 1.5e-08 33.7 0.0 2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain EF_assoc_2 PF08356.12 KFM77871.1 - 0.042 13.9 0.2 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 EF hand associated SNF2_N PF00176.23 KFM77872.1 - 5.4e-62 209.5 2.2 6.1e-62 209.4 2.2 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 KFM77872.1 - 0.0028 17.5 5.3 0.0052 16.7 5.3 1.5 1 0 0 1 1 1 1 PHD-finger Helicase_C PF00271.31 KFM77873.1 - 1.3e-11 44.8 0.0 2.7e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KFM77873.1 - 2.8e-05 23.9 12.2 2.8e-05 23.9 12.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM77873.1 - 0.00015 22.0 14.7 0.00015 22.0 14.7 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KFM77873.1 - 0.00019 21.3 13.8 0.00019 21.3 13.8 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM77873.1 - 0.00025 21.1 13.7 0.00085 19.4 13.7 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFM77873.1 - 0.00039 20.4 12.6 0.0014 18.6 12.6 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFM77873.1 - 0.0052 16.6 15.8 0.032 14.1 15.8 2.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.6 KFM77873.1 - 0.0075 16.5 4.4 0.0078 16.5 0.6 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4 PF00097.25 KFM77873.1 - 0.012 15.4 14.0 0.012 15.4 14.0 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM77873.1 - 0.026 14.4 11.7 0.63 10.0 11.7 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TPR_10 PF13374.6 KFM77873.1 - 0.026 14.4 0.1 0.11 12.4 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-UBP PF02148.19 KFM77873.1 - 0.72 10.2 11.6 0.14 12.5 7.6 2.0 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Lipase PF00151.19 KFM77874.1 - 6.8e-82 275.5 0.0 9.1e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_1 PF00561.20 KFM77874.1 - 0.00036 20.3 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase PF00151.19 KFM77875.1 - 1.3e-05 24.7 0.7 1.4e-05 24.6 0.7 1.1 1 0 0 1 1 1 1 Lipase Lipase PF00151.19 KFM77876.1 - 1.1e-62 212.4 0.0 1.3e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 Lipase Cas1_AcylT PF07779.12 KFM77877.1 - 1.5e-98 330.8 8.7 1.7e-98 330.6 8.7 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Cas1_AcylT PF07779.12 KFM77878.1 - 2.1e-89 300.7 21.9 2.2e-89 300.5 21.9 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Cas1_AcylT PF07779.12 KFM77879.1 - 3.7e-06 26.1 0.3 6e-06 25.4 0.3 1.3 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p TMEM132D_C PF15706.5 KFM77879.1 - 0.038 13.8 0.4 0.071 12.9 0.4 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term BTB PF00651.31 KFM77880.1 - 1.3e-09 38.3 0.0 9.5e-09 35.5 0.0 2.3 1 1 2 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFM77880.1 - 0.0004 20.4 0.2 0.0046 17.0 0.2 2.5 1 1 0 2 2 2 1 BTB And C-terminal Kelch Fungal_lectin_2 PF18647.1 KFM77880.1 - 0.021 15.2 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 Alpha-galactosyl-binding fungal lectin betaPIX_CC PF16523.5 KFM77880.1 - 0.089 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 betaPIX coiled coil MFS_1 PF07690.16 KFM77881.1 - 4.4e-05 22.6 3.2 5.2e-05 22.3 3.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Rft-1 PF04506.13 KFM77881.1 - 0.054 12.2 0.1 0.061 12.1 0.1 1.1 1 0 0 1 1 1 0 Rft protein DUF2721 PF11026.8 KFM77881.1 - 0.11 12.4 2.0 0.12 12.3 0.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) MFS_1 PF07690.16 KFM77882.1 - 1e-17 64.1 3.6 1.1e-17 64.0 3.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM77882.1 - 3.4e-10 39.4 2.5 3.8e-10 39.2 2.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KFM77882.1 - 0.021 13.3 0.2 0.03 12.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Glyco_hydro_18 PF00704.28 KFM77883.1 - 4.1e-68 230.4 0.3 6.1e-68 229.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KFM77884.1 - 5.3e-28 98.6 0.0 7.6e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ig_3 PF13927.6 KFM77886.1 - 2.3e-15 56.9 0.1 6.8e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM77886.1 - 6.9e-15 54.9 0.0 4.1e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFM77886.1 - 1.3e-10 41.3 0.1 9.4e-10 38.5 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM77886.1 - 2.6e-07 30.9 0.1 6.1e-07 29.7 0.1 1.6 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM77886.1 - 1.8e-05 24.9 0.5 0.0024 18.0 0.2 2.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFM77886.1 - 0.0027 17.7 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 C17orf99 Ig domain C2-set_2 PF08205.12 KFM77886.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Kazal_2 PF07648.15 KFM77887.1 - 1.1e-83 275.2 115.2 3.5e-12 46.2 8.2 10.4 10 0 0 10 10 10 8 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM77887.1 - 5.3e-60 199.2 112.3 1.2e-11 44.4 9.0 9.3 8 2 0 8 8 8 8 Kazal-type serine protease inhibitor domain FOLN PF09289.10 KFM77887.1 - 9.9 6.4 64.2 0.7 10.1 5.2 8.3 7 0 0 7 7 7 0 Follistatin/Osteonectin-like EGF domain Laminin_G_1 PF00054.23 KFM77888.1 - 3.5e-81 269.9 0.0 3.7e-26 91.9 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 KFM77888.1 - 1.5e-76 255.1 0.9 6e-27 94.7 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain EGF PF00008.27 KFM77888.1 - 1.3e-14 54.2 43.0 2.5e-07 30.8 3.8 5.0 4 0 0 4 4 4 4 EGF-like domain Laminin_G_3 PF13385.6 KFM77888.1 - 2.1e-11 44.2 0.1 4.5e-07 30.1 0.0 3.2 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Kazal_2 PF07648.15 KFM77888.1 - 9e-08 32.1 4.3 9e-08 32.1 4.3 2.7 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain hEGF PF12661.7 KFM77888.1 - 3.1e-05 24.4 40.0 0.0016 19.0 0.8 5.3 5 0 0 5 5 5 3 Human growth factor-like EGF Kazal_1 PF00050.21 KFM77888.1 - 0.00027 20.9 6.4 0.0009 19.2 6.4 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DUF378 PF04070.12 KFM77888.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF378) EGF_2 PF07974.13 KFM77888.1 - 1.2 9.6 54.7 0.11 12.9 4.8 4.8 4 0 0 4 4 4 0 EGF-like domain HEAT PF02985.22 KFM77890.1 - 8.9e-05 22.4 0.1 0.64 10.4 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat DpnI PF06044.12 KFM77892.1 - 0.03 13.9 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 Dam-replacing family GLYCAM-1 PF05242.11 KFM77894.1 - 0.019 15.1 1.5 0.022 14.9 0.1 1.8 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) NupH_GANP PF16768.5 KFM77894.1 - 0.53 9.9 5.0 2.6 7.7 0.7 2.2 2 0 0 2 2 2 0 Nucleoporin homology of Germinal-centre associated nuclear protein Rap_GAP PF02145.15 KFM77896.1 - 2.4e-44 151.1 0.0 6.2e-44 149.8 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP zf-C2H2 PF00096.26 KFM77897.1 - 0.0022 18.4 8.1 0.0049 17.2 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM77897.1 - 0.0057 17.4 7.2 0.011 16.5 7.2 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger Actin_micro PF17003.5 KFM77897.1 - 0.045 12.9 0.4 0.056 12.6 0.4 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-H2C2_2 PF13465.6 KFM77897.1 - 0.056 13.9 1.0 0.056 13.9 1.0 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2HE PF16278.5 KFM77897.1 - 0.072 13.5 4.2 0.081 13.4 4.2 1.3 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DUF4886 PF16227.5 KFM77898.1 - 0.035 13.3 0.5 0.48 9.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4886) dCMP_cyt_deam_1 PF00383.23 KFM77899.1 - 6.7e-15 54.8 0.6 1.7e-14 53.5 0.6 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFM77899.1 - 1.8e-11 44.0 0.0 6.5e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KFM77899.1 - 0.0097 16.0 0.1 0.021 14.9 0.0 1.6 2 0 0 2 2 2 1 Bd3614-like deaminase KRTAP PF11759.8 KFM77900.1 - 5.8 7.5 47.2 14 6.3 36.1 3.1 1 1 1 2 2 2 0 Keratin-associated matrix OSTMP1 PF09777.9 KFM77902.1 - 3e-33 115.2 13.7 3.9e-33 114.8 13.7 1.1 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor zinc_ribbon_15 PF17032.5 KFM77902.1 - 1.9 9.3 9.2 0.15 12.8 2.2 2.3 1 1 1 2 2 2 0 zinc-ribbon family Cytochrom_c3_2 PF14537.6 KFM77902.1 - 2.7 8.5 5.9 14 6.2 5.7 2.2 1 1 0 1 1 1 0 Cytochrome c3 Cyclin_N PF00134.23 KFM77903.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF223 PF02721.14 KFM77903.1 - 0.16 12.3 1.8 0.6 10.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF223 DUF4357 PF14267.6 KFM77904.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) Ribosomal_L22 PF00237.19 KFM77905.1 - 5.8e-24 84.3 0.1 7.3e-24 84.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SQAPI PF16845.5 KFM77905.1 - 0.14 12.5 0.2 0.23 11.9 0.2 1.3 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor SSXT PF05030.12 KFM77906.1 - 1.6e-28 98.1 0.1 1.6e-28 98.1 0.1 2.4 2 0 0 2 2 2 1 SSXT protein (N-terminal region) FAP PF07174.11 KFM77909.1 - 0.062 12.8 4.7 0.079 12.4 4.7 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF3729 PF12526.8 KFM77909.1 - 0.42 12.2 6.6 0.64 11.6 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) LRR_8 PF13855.6 KFM77911.1 - 4.2e-52 173.8 47.5 2.2e-13 49.8 4.1 6.3 3 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFM77911.1 - 6.7e-27 93.1 51.4 3.1e-06 27.4 0.6 8.9 3 1 9 12 12 12 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM77911.1 - 7.9e-18 64.7 1.4 1.2e-06 28.5 0.0 3.9 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM77911.1 - 1.2e-14 52.6 38.7 0.74 10.6 0.0 13.7 14 0 0 14 14 14 6 Leucine Rich Repeat LRR_6 PF13516.6 KFM77911.1 - 5.1e-10 38.6 49.1 0.57 10.4 0.0 11.8 12 0 0 12 12 12 5 Leucine Rich repeat LRR_9 PF14580.6 KFM77911.1 - 8.8e-06 25.3 17.0 0.0011 18.5 1.5 3.7 1 1 4 5 5 5 4 Leucine-rich repeat LRRNT PF01462.18 KFM77911.1 - 2e-05 24.1 2.1 5.1e-05 22.8 2.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain DUF3290 PF11694.8 KFM77911.1 - 2.1 8.3 5.9 3.9 7.4 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF3149 PF11346.8 KFM77911.1 - 2.6 7.8 5.0 4.8 6.9 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) An_peroxidase PF03098.15 KFM77912.1 - 7.1e-188 625.5 0.0 8.2e-188 625.3 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 KFM77914.1 - 4.5e-51 174.0 0.2 4.8e-51 173.9 0.2 1.0 1 0 0 1 1 1 1 Animal haem peroxidase MFS_1 PF07690.16 KFM77915.1 - 3.1e-51 174.4 34.0 1.4e-48 165.7 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM77915.1 - 3.7e-07 29.4 7.4 3.7e-07 29.4 7.4 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter PrmA PF06325.13 KFM77916.1 - 1.6e-08 34.3 0.0 9e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFM77916.1 - 3.4e-05 24.5 0.0 0.00013 22.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM77916.1 - 0.0031 17.4 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KFM77916.1 - 0.0035 16.4 0.0 0.0099 15.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 KFM77916.1 - 0.0073 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KFM77916.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM77916.1 - 0.048 13.3 0.0 0.17 11.5 0.0 1.9 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5_C PF17286.2 KFM77916.1 - 0.064 13.1 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 PRMT5 oligomerisation domain Ntox10 PF15520.6 KFM77916.1 - 0.078 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Novel toxin 10 Methyltransf_11 PF08241.12 KFM77916.1 - 0.094 13.4 0.0 0.25 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain EamA PF00892.20 KFM77917.1 - 3.1e-05 24.2 2.4 3.1e-05 24.2 2.4 2.9 4 0 0 4 4 4 1 EamA-like transporter family PUNUT PF16913.5 KFM77917.1 - 0.0018 17.5 5.4 0.0023 17.2 5.4 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport FAD_binding_7 PF03441.14 KFM77917.1 - 0.0032 17.0 0.1 0.0049 16.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase SLC35F PF06027.12 KFM77917.1 - 0.012 15.2 6.6 0.02 14.4 6.6 1.3 1 0 0 1 1 1 0 Solute carrier family 35 SH3_9 PF14604.6 KFM77918.1 - 5.4e-17 61.4 0.2 1.3e-16 60.1 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFM77918.1 - 2e-15 56.1 0.2 6.7e-15 54.4 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFM77918.1 - 5.7e-11 41.9 0.0 9.9e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.16 KFM77918.1 - 0.00018 21.6 0.1 0.00032 20.8 0.1 1.5 1 0 0 1 1 1 1 Hr1 repeat adh_short PF00106.25 KFM77919.1 - 3e-13 49.7 0.0 3.4e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM77919.1 - 1.6e-10 41.0 0.0 1.7e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFM77919.1 - 0.12 11.9 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KFM77920.1 - 4.8e-32 111.0 0.0 3.9e-25 88.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFM77920.1 - 5.4e-22 78.5 0.0 1.7e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM77920.1 - 1.2e-07 31.9 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM77920.1 - 3.3e-05 23.5 0.0 0.00068 19.2 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFM77920.1 - 0.0084 15.3 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein HATPase_c PF02518.26 KFM77920.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glycos_transf_1 PF00534.20 KFM77923.1 - 6.9e-25 87.6 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM77923.1 - 2.6e-20 73.2 0.1 4.5e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFM77923.1 - 1.2e-10 41.6 0.0 2.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 PIGA PF08288.12 KFM77923.1 - 3.5e-08 33.9 2.1 4.4e-08 33.6 0.7 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_trans_1_2 PF13524.6 KFM77923.1 - 0.036 14.4 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFM77924.1 - 2e-06 27.9 0.1 2.3e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KFM77924.1 - 0.00045 20.0 0.0 0.00049 19.9 0.0 1.0 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 KFM77924.1 - 0.014 15.8 0.0 0.015 15.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain T_hemolysin PF12261.8 KFM77924.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.0 1 0 0 1 1 1 0 Thermostable hemolysin Ras PF00071.22 KFM77925.1 - 2.4e-13 50.0 0.1 2.6e-13 49.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM77925.1 - 2.3e-08 34.3 0.0 3.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase A_deaminase PF00962.22 KFM77926.1 - 1e-22 80.9 0.5 9.6e-22 77.7 0.1 2.1 2 0 0 2 2 2 1 Adenosine/AMP deaminase A_deaminase PF00962.22 KFM77927.1 - 1.3e-73 248.2 0.0 1.5e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Selenoprotein_S PF06936.11 KFM77928.1 - 2.1e-34 119.0 21.3 8.8e-26 90.9 5.5 2.0 1 1 1 2 2 2 2 Selenoprotein S (SelS) DUF1823 PF08853.11 KFM77928.1 - 0.008 16.4 0.6 0.011 15.9 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1823) Vma12 PF11712.8 KFM77928.1 - 0.0098 16.0 2.8 9.2 6.3 0.0 2.1 1 1 1 2 2 2 2 Endoplasmic reticulum-based factor for assembly of V-ATPase PV-1 PF06637.11 KFM77928.1 - 0.081 11.7 5.8 0.1 11.4 5.8 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Atg14 PF10186.9 KFM77928.1 - 0.088 11.9 4.3 0.1 11.7 4.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 THOC2_N PF16134.5 KFM77928.1 - 0.089 11.4 4.4 0.11 11.1 4.4 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Colicin PF01024.19 KFM77928.1 - 1.1 9.1 3.1 1.5 8.7 3.1 1.2 1 0 0 1 1 1 0 Colicin pore forming domain YnfE PF17452.2 KFM77928.1 - 3.9 7.8 10.4 0.19 12.1 3.2 2.3 1 1 1 2 2 2 0 Uncharacterized YnfE-like zf-LYAR PF08790.11 KFM77929.1 - 4.7e-16 58.4 2.0 4.7e-16 58.4 2.0 2.7 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger NPM1-C PF16276.5 KFM77929.1 - 0.00014 21.8 0.5 0.00014 21.8 0.5 2.4 2 0 0 2 2 2 1 Nucleophosmin C-terminal domain AAA_lid_7 PF17867.1 KFM77929.1 - 0.0014 18.8 0.0 0.038 14.2 0.0 2.2 2 0 0 2 2 2 1 Midasin AAA lid domain zf_UBZ PF18439.1 KFM77929.1 - 0.028 14.0 0.6 1.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 KFM77929.1 - 0.61 10.2 5.3 2.4 8.3 5.3 2.1 1 1 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain CTD_bind PF04818.13 KFM77930.1 - 1.1e-15 58.2 0.1 1.1e-15 58.2 0.1 3.0 4 0 0 4 4 4 1 RNA polymerase II-binding domain. CREPT PF16566.5 KFM77930.1 - 0.00011 22.4 0.9 0.00011 22.4 0.9 2.2 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour RTX_C PF08339.10 KFM77930.1 - 0.15 12.1 4.1 0.46 10.5 1.0 2.8 1 1 1 2 2 2 0 RTX C-terminal domain Baculo_PEP_C PF04513.12 KFM77930.1 - 5.8 7.0 7.4 1.7 8.7 0.4 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.21 KFM77931.1 - 1e-14 54.4 15.6 2.4e-14 53.2 15.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM77931.1 - 1.7e-09 37.6 11.2 4.7e-09 36.2 11.2 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFM77931.1 - 3.8e-07 30.5 11.1 8e-07 29.5 11.1 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF4407 PF14362.6 KFM77931.1 - 0.012 15.0 0.2 0.018 14.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 KFM77931.1 - 0.023 12.7 3.1 0.055 11.4 3.1 1.6 1 0 0 1 1 1 0 Prominin KASH_CCD PF14662.6 KFM77931.1 - 0.08 12.8 13.2 0.18 11.7 13.2 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HAUS-augmin3 PF14932.6 KFM77931.1 - 0.16 11.5 6.2 0.21 11.2 5.2 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 IMD PF08397.11 KFM77931.1 - 0.19 11.0 7.3 0.4 10.0 7.3 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain UPF0242 PF06785.11 KFM77931.1 - 1.5 8.9 9.8 3.2 7.8 9.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KFM77931.1 - 4.4 7.8 11.8 0.81 10.2 7.6 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region NICE-3 PF07406.11 KFM77932.1 - 1.4e-52 178.3 0.1 1.9e-52 177.9 0.1 1.1 1 0 0 1 1 1 1 NICE-3 protein SH2 PF00017.24 KFM77933.1 - 4e-10 39.6 0.1 8.6e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 SH2 domain DUF4507 PF14964.6 KFM77934.1 - 5.2e-68 229.6 0.9 5.7e-68 229.4 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) Anoct_dimer PF16178.5 KFM77935.1 - 0.031 14.0 0.1 0.031 14.0 0.1 1.0 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Anoctamin PF04547.12 KFM77936.1 - 5.7e-40 137.5 1.5 6.3e-40 137.4 1.5 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoctamin PF04547.12 KFM77937.1 - 4.1e-55 187.4 0.6 4.6e-55 187.2 0.6 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Ctr PF04145.15 KFM77937.1 - 0.051 14.2 0.3 0.077 13.6 0.3 1.4 1 1 0 1 1 1 0 Ctr copper transporter family Peptidase_S8 PF00082.22 KFM77939.1 - 1.2e-49 169.2 3.1 1.2e-49 169.2 3.1 1.5 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 KFM77939.1 - 4.6e-28 97.1 0.0 1e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFM77939.1 - 2.3e-21 76.3 2.3 1.3e-20 74.0 2.7 2.0 2 0 0 2 2 2 1 Peptidase S8 pro-domain OmpA_membrane PF01389.17 KFM77939.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 OmpA-like transmembrane domain Peptidase_S10 PF00450.22 KFM77940.1 - 3.8e-84 283.5 0.0 4.5e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase LPD14 PF18827.1 KFM77940.1 - 0.0098 16.2 0.0 0.03 14.6 0.0 1.7 2 0 0 2 2 2 1 Large polyvalent protein-associated domain 14 Peptidase_S9 PF00326.21 KFM77940.1 - 0.03 13.8 0.0 0.096 12.1 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFM77940.1 - 0.079 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NTR PF01759.21 KFM77941.1 - 0.012 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module GAIN PF16489.5 KFM77943.1 - 1.1e-13 51.1 0.7 1.3e-13 50.8 0.7 1.0 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain N1221 PF07923.13 KFM77943.1 - 0.00091 18.5 0.1 0.0011 18.2 0.1 1.1 1 0 0 1 1 1 1 N1221-like protein PRANC PF09372.10 KFM77943.1 - 0.0095 16.2 0.0 0.022 15.1 0.0 1.6 1 1 0 1 1 1 1 PRANC domain RseA_N PF03872.13 KFM77943.1 - 0.017 15.6 0.1 0.024 15.1 0.1 1.5 1 1 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain Mis12 PF05859.12 KFM77943.1 - 0.052 13.6 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Mis12 protein Gal_Lectin PF02140.18 KFM77944.1 - 1.3e-19 70.4 0.5 1.6e-19 70.1 0.5 1.1 1 0 0 1 1 1 1 Galactose binding lectin domain DUF3395 PF11875.8 KFM77944.1 - 0.042 13.8 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) ROQ_II PF18386.1 KFM77945.1 - 2.6e-33 113.6 0.1 4.9e-33 112.7 0.1 1.5 1 0 0 1 1 1 1 Roquin II domain zf-CCCH PF00642.24 KFM77945.1 - 9.1e-08 31.8 1.1 1.9e-07 30.8 1.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM77945.1 - 0.00016 21.6 0.7 0.00041 20.3 0.7 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFM77945.1 - 0.00049 19.8 0.5 0.0013 18.5 0.5 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger DUF743 PF05332.11 KFM77945.1 - 0.021 14.9 0.0 0.08 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF743) PaaA_PaaC PF05138.12 KFM77945.1 - 0.022 13.9 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein Ank_4 PF13637.6 KFM77947.1 - 2.1e-11 44.1 0.3 8.3e-07 29.4 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM77947.1 - 1.9e-09 37.6 0.2 2.9e-08 33.8 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM77947.1 - 4.1e-06 26.7 0.1 0.00015 21.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KFM77947.1 - 4.9e-05 23.8 0.0 5.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM77947.1 - 0.0069 16.8 0.0 0.99 10.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat RNase_P_p30 PF01876.16 KFM77947.1 - 0.1 12.1 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 RNase P subunit p30 Ank_5 PF13857.6 KFM77948.1 - 2.8e-13 49.8 0.4 3.6e-07 30.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM77948.1 - 4.1e-12 46.5 0.4 2.4e-11 44.0 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM77948.1 - 1e-09 37.8 2.1 2e-05 24.6 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFM77948.1 - 2.8e-09 37.3 0.3 9.9e-06 26.0 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM77948.1 - 5.6e-08 32.9 2.6 8.8e-05 22.8 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat RsgA_GTPase PF03193.16 KFM77948.1 - 0.011 15.6 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KFM77948.1 - 0.051 13.3 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KFM77948.1 - 0.061 13.0 0.1 0.16 11.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM77948.1 - 0.067 13.7 0.1 0.22 12.0 0.1 1.7 2 0 0 2 2 2 0 ABC transporter G-alpha PF00503.20 KFM77948.1 - 0.2 10.8 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Death PF00531.22 KFM77950.1 - 1.6e-11 44.2 0.0 5.5e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Death domain COR PF16095.5 KFM77950.1 - 1.3e-06 28.3 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain CZB PF13682.6 KFM77950.1 - 0.11 12.9 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Chemoreceptor zinc-binding domain WD40 PF00400.32 KFM77951.1 - 1.8e-37 126.7 13.5 1.1e-08 35.6 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM77951.1 - 9.1e-10 38.7 0.0 0.043 14.1 0.0 4.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM77951.1 - 2.2e-06 27.7 0.0 0.02 14.8 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFM77951.1 - 1.8e-05 24.2 0.2 0.43 9.9 0.0 3.9 2 1 2 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 KFM77951.1 - 0.0012 17.9 0.1 1.5 7.7 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ig_3 PF13927.6 KFM77952.1 - 1.7e-24 86.2 0.0 2.3e-09 37.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFM77952.1 - 2.1e-22 79.0 0.0 4.7e-11 42.6 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM77952.1 - 7.1e-14 51.9 0.0 0.0005 20.4 0.0 3.3 2 1 1 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM77952.1 - 3.5e-10 39.9 0.0 0.00057 20.0 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFM77952.1 - 4.1e-06 26.9 0.2 0.9 9.7 0.0 4.6 3 3 1 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM77952.1 - 0.0011 19.0 0.0 0.053 13.6 0.0 2.7 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM77952.1 - 0.0059 16.2 0.0 0.026 14.1 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.15 KFM77952.1 - 0.0067 16.8 0.1 2.5 8.5 0.0 3.5 3 1 0 3 3 3 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM77952.1 - 0.008 16.4 0.1 3.1 8.1 0.0 2.7 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain OLF PF02191.16 KFM77953.1 - 2.1e-70 237.1 2.6 3.3e-70 236.5 2.6 1.3 1 0 0 1 1 1 1 Olfactomedin-like domain Ig_3 PF13927.6 KFM77953.1 - 8.9e-23 80.7 0.1 8.9e-13 48.7 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM77953.1 - 2.2e-16 59.7 0.0 5.5e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM77953.1 - 4.9e-12 46.0 0.2 8.5e-07 29.2 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFM77953.1 - 1.6e-11 44.2 0.0 6.2e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM77953.1 - 3.5e-05 23.9 0.0 0.053 13.7 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM77953.1 - 0.001 18.6 0.0 0.035 13.7 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain EII-GUT PF03608.13 KFM77953.1 - 0.0067 16.3 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 PTS system enzyme II sorbitol-specific factor C2-set_2 PF08205.12 KFM77953.1 - 0.013 15.6 0.0 0.068 13.2 0.0 2.1 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM77954.1 - 5e-69 228.9 1.2 1.4e-14 54.4 0.1 6.5 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFM77954.1 - 2.7e-59 197.2 0.0 6.2e-16 58.2 0.0 6.5 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM77954.1 - 1.7e-46 156.4 3.7 8.4e-09 35.6 0.1 6.3 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFM77954.1 - 1.2e-41 140.7 0.0 6.1e-11 42.3 0.0 6.7 6 1 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 KFM77954.1 - 6.8e-19 68.1 7.2 0.055 13.6 0.0 9.5 6 4 1 7 7 7 4 Immunoglobulin V-set domain fn3 PF00041.21 KFM77954.1 - 1.4e-12 47.8 2.8 1.1e-06 28.9 0.1 3.2 2 1 0 2 2 2 2 Fibronectin type III domain Ig_6 PF18452.1 KFM77954.1 - 2.6e-08 33.3 1.4 0.11 12.1 0.0 5.5 5 0 0 5 5 5 2 Immunoglobulin domain Ig_5 PF16681.5 KFM77954.1 - 3.1e-06 27.5 0.3 2.7 8.5 0.3 5.4 6 1 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFM77954.1 - 4.1e-06 26.8 0.2 1.9 8.6 0.0 5.6 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM77954.1 - 2.8e-05 24.1 0.0 0.097 12.7 0.0 4.9 5 0 0 5 5 5 1 C17orf99 Ig domain Ig_4 PF16680.5 KFM77954.1 - 0.0017 18.6 0.8 1.7 8.9 0.2 5.0 5 1 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain DUF2914 PF11141.8 KFM77954.1 - 0.068 12.9 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) C2-set PF05790.15 KFM77954.1 - 0.07 13.3 0.0 18 5.6 0.0 4.1 5 0 0 5 5 4 0 Immunoglobulin C2-set domain fn3 PF00041.21 KFM77955.1 - 3.7e-15 56.0 0.1 5.7e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM77955.1 - 1.8e-06 28.4 0.0 2.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Trypsin PF00089.26 KFM77956.1 - 7.1e-53 179.7 0.1 9.7e-53 179.2 0.1 1.2 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 KFM77956.1 - 3.3e-09 36.8 16.5 4e-09 36.5 15.1 1.9 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Trypsin_2 PF13365.6 KFM77956.1 - 3e-08 34.7 0.0 4.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM77956.1 - 2.4e-07 31.1 0.0 1.4e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Aminotran_1_2 PF00155.21 KFM77957.1 - 8.1e-32 110.8 0.0 1e-31 110.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFM77957.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase hSac2 PF12456.8 KFM77957.1 - 0.11 12.2 0.0 7.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Inositol phosphatase Aminotran_5 PF00266.19 KFM77957.1 - 0.16 10.9 0.0 0.57 9.1 0.0 1.8 2 1 0 2 2 2 0 Aminotransferase class-V DUF4874 PF16173.5 KFM77957.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) FMO-like PF00743.19 KFM77958.1 - 1.2e-155 519.0 0.0 1.4e-155 518.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM77958.1 - 4e-17 62.4 0.1 1.6e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM77958.1 - 6.3e-12 45.3 0.0 1.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM77958.1 - 1.1e-07 31.3 0.4 0.00015 21.0 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFM77958.1 - 2.4e-05 24.8 0.7 0.25 12.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM77958.1 - 2.6e-05 24.4 0.2 0.0002 21.5 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFM77958.1 - 0.0012 18.9 1.4 2.4 8.1 0.0 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Peptidase_M17_N PF02789.17 KFM77958.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain FAD_binding_2 PF00890.24 KFM77958.1 - 0.041 13.0 0.4 2 7.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Evr1_Alr PF04777.13 KFM77958.1 - 0.045 14.2 0.1 0.092 13.2 0.1 1.5 1 0 0 1 1 1 0 Erv1 / Alr family AlaDh_PNT_C PF01262.21 KFM77958.1 - 0.15 11.3 0.2 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain RhoGEF PF00621.20 KFM77960.1 - 1.1e-33 117.0 4.3 1.1e-33 117.0 4.3 2.0 2 0 0 2 2 2 1 RhoGEF domain HLH PF00010.26 KFM77961.1 - 4.3e-17 61.8 2.2 8.7e-17 60.8 2.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CNDH2_C PF16858.5 KFM77961.1 - 0.05 13.5 6.6 0.064 13.1 6.6 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Pes-10 PF07149.11 KFM77961.1 - 0.77 8.7 5.0 1.1 8.3 5.0 1.1 1 0 0 1 1 1 0 Pes-10 fn3 PF00041.21 KFM77963.1 - 5.7e-94 308.6 40.6 1.1e-12 48.1 0.2 12.3 12 0 0 12 12 12 12 Fibronectin type III domain Y_phosphatase PF00102.27 KFM77963.1 - 2.3e-84 282.7 0.6 4.6e-84 281.7 0.6 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM77963.1 - 4.5e-06 26.5 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pur_ac_phosph_N PF16656.5 KFM77963.1 - 7.1e-06 26.5 18.1 0.17 12.5 0.0 9.7 7 3 0 7 7 7 2 Purple acid Phosphatase, N-terminal domain PTP_tm PF18861.1 KFM77963.1 - 4.3e-05 23.6 0.2 0.00019 21.5 0.2 2.1 1 1 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Tissue_fac PF01108.17 KFM77963.1 - 0.0016 18.3 8.6 0.0079 16.0 0.2 4.9 5 0 0 5 5 5 1 Tissue factor TMEM154 PF15102.6 KFM77963.1 - 0.0093 15.9 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family Y_phosphatase3 PF13350.6 KFM77963.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM77963.1 - 0.079 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF4945 PF16303.5 KFM77963.1 - 0.088 12.7 0.0 19 5.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4945) RAMP PF04901.13 KFM77963.1 - 0.11 12.5 1.0 8.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Receptor activity modifying family DSPc PF00782.20 KFM77964.1 - 4.9e-39 133.2 0.0 1.4e-38 131.7 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFM77964.1 - 8.5e-12 45.6 0.0 2.3e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase PF00102.27 KFM77964.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TFIIF_beta_N PF17683.1 KFM77964.1 - 0.02 15.6 0.6 0.048 14.4 0.6 1.6 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus Collar PF07484.12 KFM77966.1 - 0.083 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Phage Tail Collar Domain TspO_MBR PF03073.15 KFM77967.1 - 2.3e-50 170.1 14.1 2.6e-50 170.0 14.1 1.0 1 0 0 1 1 1 1 TspO/MBR family Adaptin_N PF01602.20 KFM77968.1 - 3.1e-148 494.6 7.8 3.8e-148 494.3 7.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KFM77968.1 - 7.7e-44 148.5 0.2 1.9e-42 144.0 0.0 3.0 3 0 0 3 3 3 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KFM77968.1 - 1.4e-19 70.4 0.9 4.9e-19 68.7 0.9 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFM77968.1 - 5.1e-05 23.4 0.7 0.002 18.2 0.0 3.0 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KFM77968.1 - 0.00013 22.0 0.0 0.00069 19.7 0.0 2.3 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KFM77968.1 - 0.00065 20.0 0.6 0.021 15.2 0.1 3.7 3 1 1 4 4 4 1 HEAT repeats RIX1 PF08167.12 KFM77968.1 - 0.002 17.9 0.5 0.21 11.3 0.1 3.3 2 1 1 3 3 3 1 rRNA processing/ribosome biogenesis HEAT PF02985.22 KFM77968.1 - 0.033 14.4 2.0 71 4.1 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat DUF4003 PF13170.6 KFM77968.1 - 0.13 11.6 3.1 0.28 10.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) PRAS PF15798.5 KFM77969.1 - 2.4e-16 60.4 1.6 3.2e-16 60.1 0.3 1.9 1 1 1 2 2 2 1 Proline-rich AKT1 substrate 1 ZYG-11_interact PF05884.12 KFM77969.1 - 0.032 13.7 0.6 0.046 13.1 0.6 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF1759 PF03564.15 KFM77970.1 - 9.6e-15 54.8 0.6 2.3e-14 53.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) zf-C2H2_11 PF16622.5 KFM77971.1 - 0.001 18.8 1.9 0.001 18.8 1.9 3.2 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFM77971.1 - 0.059 14.2 32.3 0.015 16.1 2.8 6.1 4 0 0 4 4 4 0 C2H2-type zinc finger Acetyltransf_1 PF00583.25 KFM77973.1 - 8.5e-12 45.3 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM77973.1 - 7.1e-06 26.4 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM77973.1 - 2.2e-05 24.4 0.0 3.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM77973.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein ING PF12998.7 KFM77974.1 - 2.7e-31 108.2 6.0 2.7e-31 108.2 6.0 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFM77974.1 - 1e-06 28.5 9.3 1.7e-06 27.8 9.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFM77974.1 - 0.035 14.4 0.2 0.083 13.2 0.2 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain LXG PF04740.12 KFM77974.1 - 0.056 13.1 1.1 0.31 10.7 1.1 2.1 1 1 0 1 1 1 0 LXG domain of WXG superfamily UPF0242 PF06785.11 KFM77974.1 - 0.06 13.5 6.7 0.044 13.9 4.3 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMEM132D_N PF15705.5 KFM77974.1 - 0.092 12.6 0.3 0.25 11.2 0.3 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term TRCF PF03461.15 KFM77974.1 - 0.32 11.4 3.4 6.6 7.2 0.8 2.6 2 0 0 2 2 2 0 TRCF domain DUF3450 PF11932.8 KFM77974.1 - 5.9 6.1 14.9 0.99 8.7 6.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Peptidase_C1 PF00112.23 KFM77975.1 - 1.8e-72 244.0 1.6 3.3e-72 243.1 1.6 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM77975.1 - 2.5e-10 40.7 2.5 2.5e-10 40.7 2.5 2.6 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM77975.1 - 0.0077 15.1 1.8 0.1 11.3 0.1 2.4 3 0 0 3 3 3 1 Peptidase C1-like family FluMu_N PF17891.1 KFM77975.1 - 0.051 13.3 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Mu-like prophage FluMu N-terminal domain Proteasome PF00227.26 KFM77976.1 - 1.6e-59 200.6 0.1 1.9e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM77976.1 - 6.1e-14 51.4 0.0 1.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CD4-extracel PF09191.10 KFM77977.1 - 0.0031 17.9 0.4 0.021 15.2 0.4 2.5 1 0 0 1 1 1 1 CD4, extracellular HU-DNA_bdg PF14848.6 KFM77977.1 - 0.006 16.6 1.5 0.094 12.7 0.3 2.8 2 0 0 2 2 2 1 DNA-binding domain DUF2607 PF10795.9 KFM77978.1 - 0.11 12.7 0.5 0.37 11.0 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2607) Vps39_1 PF10366.9 KFM77980.1 - 0.093 13.0 2.3 0.22 11.8 0.5 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Adap_comp_sub PF00928.21 KFM77982.1 - 9.9e-44 149.7 0.3 1.1e-43 149.5 0.3 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 KFM77982.1 - 0.0027 17.2 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain G_glu_transpept PF01019.21 KFM77983.1 - 3.4e-50 171.3 0.0 3.8e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.21 KFM77984.1 - 6.1e-44 150.7 0.0 7e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.21 KFM77986.1 - 8.2e-51 173.3 0.0 9.1e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Reg_prop PF07494.11 KFM77986.1 - 0.068 13.4 0.9 14 6.3 0.0 3.3 3 0 0 3 3 3 0 Two component regulator propeller CARM1 PF11531.8 KFM77988.1 - 0.018 15.2 0.2 0.018 15.2 0.2 1.0 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal JmjC PF02373.22 KFM77989.1 - 8.6e-12 45.5 0.0 8.6e-12 45.5 0.0 3.1 3 0 0 3 3 3 1 JmjC domain, hydroxylase FYVE PF01363.21 KFM77989.1 - 0.028 14.5 3.5 0.12 12.5 3.5 2.1 1 0 0 1 1 1 0 FYVE zinc finger zf-C5HC2 PF02928.16 KFM77989.1 - 0.064 13.7 6.0 0.16 12.4 6.0 1.7 1 0 0 1 1 1 0 C5HC2 zinc finger Zn_ribbon_17 PF17120.5 KFM77989.1 - 0.22 11.2 4.6 0.54 9.9 4.6 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-UBP PF02148.19 KFM77989.1 - 0.26 11.6 5.2 1 9.8 5.2 2.0 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C3HC4_3 PF13920.6 KFM77989.1 - 0.6 10.0 5.4 1.7 8.6 5.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 KFM77989.1 - 1.3 9.4 10.0 0.2 12.0 5.6 2.0 2 0 0 2 2 2 0 C1 domain BBIP10 PF14777.6 KFM77990.1 - 8.1e-23 79.8 4.0 9.4e-23 79.6 4.0 1.1 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 Ribosomal_S7 PF00177.21 KFM77992.1 - 1.8e-25 89.3 5.6 6.1e-22 77.9 0.8 2.0 1 1 1 2 2 2 2 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.21 KFM77993.1 - 4.6e-24 84.8 6.1 1.3e-20 73.6 1.1 2.0 1 1 1 2 2 2 2 Ribosomal protein S7p/S5e Ribosomal_L4 PF00573.22 KFM77994.1 - 4e-18 65.8 0.0 5e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L4 PF00573.22 KFM77995.1 - 2.8e-11 43.5 0.0 2.9e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family WD40 PF00400.32 KFM77996.1 - 0.0048 17.7 0.2 0.057 14.3 0.2 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Dimer_Tnp_hAT PF05699.14 KFM77998.1 - 1.7e-08 34.2 0.0 4.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Hormone_recep PF00104.30 KFM77998.1 - 0.0068 16.0 0.8 0.019 14.5 0.3 2.1 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor DapH_N PF08503.10 KFM77998.1 - 0.028 14.7 0.1 0.4 10.9 0.0 2.7 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal Baculo_LEF-11 PF06385.12 KFM77998.1 - 0.19 12.2 2.5 17 5.9 0.1 3.0 1 1 2 3 3 3 0 Baculovirus LEF-11 protein Peptidase_A17 PF05380.13 KFM77999.1 - 3.6e-29 101.9 0.0 8.6e-14 51.9 0.0 2.9 2 1 1 3 3 3 2 Pao retrotransposon peptidase RVT_1 PF00078.27 KFM77999.1 - 1.7e-07 31.0 0.1 3.3e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RESP18 PF14948.6 KFM77999.1 - 0.058 13.7 0.2 2.9 8.3 0.0 2.9 3 0 0 3 3 3 0 RESP18 domain FAD_binding_6 PF00970.24 KFM78000.1 - 2e-36 124.3 0.0 3.5e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFM78000.1 - 1.7e-29 102.7 0.0 2.6e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFM78000.1 - 0.00075 19.7 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Rabaptin PF03528.15 KFM78002.1 - 2.9e-38 131.8 13.4 3.1e-38 131.7 13.4 1.0 1 0 0 1 1 1 1 Rabaptin Rab5-bind PF09311.11 KFM78003.1 - 1.3e-13 51.1 15.0 1.3e-13 51.1 15.0 1.7 2 0 0 2 2 2 1 Rabaptin-like protein Cas_DxTHG PF09455.10 KFM78003.1 - 0.0002 21.1 1.8 0.00023 20.9 1.8 1.0 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family BST2 PF16716.5 KFM78003.1 - 0.00074 20.1 19.6 0.0063 17.1 10.5 3.0 2 1 1 3 3 3 1 Bone marrow stromal antigen 2 MOLO1 PF17175.4 KFM78003.1 - 0.0075 16.4 3.0 0.012 15.7 3.0 1.4 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 DUF4446 PF14584.6 KFM78003.1 - 0.18 11.8 4.8 0.33 10.9 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2207 PF09972.9 KFM78003.1 - 0.29 9.8 1.1 0.29 9.9 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TPR_MLP1_2 PF07926.12 KFM78003.1 - 0.31 11.1 18.9 0.49 10.5 11.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ApoO PF09769.9 KFM78003.1 - 0.34 10.9 3.4 7.7 6.5 0.6 2.3 1 1 1 2 2 2 0 Apolipoprotein O TMPIT PF07851.13 KFM78003.1 - 0.35 10.1 9.3 0.49 9.6 9.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Ima1_N PF09779.9 KFM78003.1 - 0.41 11.5 9.7 0.69 10.8 9.8 1.5 1 1 0 1 1 1 0 Ima1 N-terminal domain Exonuc_VII_L PF02601.15 KFM78003.1 - 0.77 9.3 6.9 0.92 9.0 6.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KFM78003.1 - 1.2 9.2 5.3 1 9.4 2.1 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4337 PF14235.6 KFM78003.1 - 1.7 8.7 5.6 2.8 8.1 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FapA PF03961.13 KFM78003.1 - 2.1 6.9 7.7 2.5 6.6 7.7 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A ERM PF00769.19 KFM78003.1 - 3.3 7.5 23.6 0.17 11.7 18.0 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF745 PF05335.13 KFM78003.1 - 5.3 6.7 9.7 4.9 6.8 8.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) LMBR1 PF04791.16 KFM78003.1 - 5.4 5.8 4.3 5.6 5.8 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CREPT PF16566.5 KFM78003.1 - 6.3 7.0 13.6 4.8 7.4 9.5 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Rab5-bind PF09311.11 KFM78004.1 - 2.8e-49 168.2 27.1 1.2e-48 166.1 27.1 1.8 2 0 0 2 2 2 1 Rabaptin-like protein FYVE PF01363.21 KFM78004.1 - 1.4e-11 44.3 13.7 2.7e-11 43.4 13.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger CCDC144C PF14915.6 KFM78004.1 - 0.0025 17.0 23.3 0.012 14.8 11.4 2.3 1 1 1 2 2 2 2 CCDC144C protein coiled-coil region IBR PF01485.21 KFM78004.1 - 0.0043 17.2 6.1 0.0043 17.2 6.1 2.1 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain Spc7 PF08317.11 KFM78004.1 - 0.0043 16.0 12.1 0.0043 16.0 12.1 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein Trimer_CC PF08954.11 KFM78004.1 - 0.0064 16.0 1.5 0.042 13.4 0.2 2.7 1 1 1 2 2 2 1 Trimerisation motif HypA PF01155.19 KFM78004.1 - 0.0067 16.4 5.3 0.0067 16.4 5.3 2.4 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_5 PF14634.6 KFM78004.1 - 0.016 15.1 14.7 0.11 12.5 15.4 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Tropomyosin_1 PF12718.7 KFM78004.1 - 0.019 15.2 5.6 0.019 15.2 5.6 3.0 1 1 2 3 3 1 0 Tropomyosin like His_Me_b4a2 PF18275.1 KFM78004.1 - 0.035 14.2 0.1 0.035 14.2 0.1 2.1 2 0 0 2 2 1 0 His-Me finger endonuclease beta4-alpha2 domain Gp58 PF07902.11 KFM78004.1 - 0.074 11.3 6.9 0.096 11.0 6.9 1.1 1 0 0 1 1 1 0 gp58-like protein HOOK PF05622.12 KFM78004.1 - 0.074 11.2 24.2 0.12 10.5 24.2 1.3 1 0 0 1 1 1 0 HOOK protein Fez1 PF06818.15 KFM78004.1 - 0.087 13.3 22.9 0.13 12.7 7.8 2.3 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 KFM78004.1 - 0.14 11.5 10.0 0.22 10.8 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 KFM78004.1 - 0.16 12.4 12.5 0.46 11.0 0.8 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein C1_4 PF07975.12 KFM78004.1 - 0.19 12.0 12.6 3.1 8.1 11.7 2.9 1 1 0 1 1 1 0 TFIIH C1-like domain Lzipper-MIP1 PF14389.6 KFM78004.1 - 0.21 11.9 23.6 0.46 10.8 10.3 4.4 2 2 2 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 MAP65_ASE1 PF03999.12 KFM78004.1 - 0.25 10.0 20.6 0.35 9.5 20.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) zf-AN1 PF01428.16 KFM78004.1 - 0.27 11.4 13.3 4.4 7.5 13.7 2.5 1 1 1 2 2 2 0 AN1-like Zinc finger DUF1664 PF07889.12 KFM78004.1 - 0.5 10.4 11.6 0.063 13.3 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KFM78004.1 - 0.74 10.1 15.4 0.16 12.3 2.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 KFM78004.1 - 0.79 9.8 11.5 1.8 8.6 2.7 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 KFM78004.1 - 1.1 9.7 8.4 0.49 10.8 0.5 3.4 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Pox_A_type_inc PF04508.12 KFM78004.1 - 1.3 9.0 8.0 0.27 11.1 1.7 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Zn_Tnp_IS1595 PF12760.7 KFM78004.1 - 1.8 8.6 9.1 0.05 13.6 2.1 2.1 2 0 0 2 2 1 0 Transposase zinc-ribbon domain BLOC1_2 PF10046.9 KFM78004.1 - 1.8 8.9 13.2 0.13 12.5 6.9 2.3 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 KFM78004.1 - 2.1 8.5 24.9 1.4 9.1 21.1 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) zinc-ribbons_6 PF07191.12 KFM78004.1 - 2.7 8.0 14.0 3.9 7.5 11.3 2.8 2 1 0 2 2 2 0 zinc-ribbons zf-C3HC4 PF00097.25 KFM78004.1 - 3.2 7.7 13.0 8 6.4 13.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tup_N PF08581.10 KFM78004.1 - 3.9 7.8 27.2 0.054 13.8 4.6 4.1 3 1 2 5 5 4 0 Tup N-terminal PHD PF00628.29 KFM78004.1 - 5.1 7.1 12.3 14 5.7 0.4 2.5 1 1 1 2 2 2 0 PHD-finger ADIP PF11559.8 KFM78004.1 - 5.3 7.1 23.5 4 7.5 7.2 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding zf-RING_2 PF13639.6 KFM78004.1 - 6.6 7.2 15.1 1.5 9.2 11.6 1.8 2 0 0 2 2 1 0 Ring finger domain Bacillus_HBL PF05791.11 KFM78004.1 - 7.8 6.3 14.7 0.28 11.0 4.3 2.3 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin-6_N PF09177.11 KFM78004.1 - 8.1 7.1 11.2 4 8.1 6.4 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FapA PF03961.13 KFM78004.1 - 9.1 4.8 15.8 25 3.3 15.8 1.7 1 1 0 1 1 1 0 Flagellar Assembly Protein A L27_N PF09060.10 KFM78005.1 - 0.4 10.8 1.6 0.45 10.6 0.3 1.7 2 0 0 2 2 2 0 L27_N CBM_14 PF01607.24 KFM78006.1 - 1.5e-05 25.0 1.5 2.8e-05 24.2 1.5 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF919 PF06034.11 KFM78009.1 - 3.9 7.4 7.1 1.3 8.9 0.3 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) CBM_14 PF01607.24 KFM78010.1 - 7.1e-09 35.7 6.6 1.3e-08 34.8 6.6 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF4118 PF13493.6 KFM78012.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DUF4586 PF15239.6 KFM78012.1 - 0.018 15.3 0.0 0.021 15.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) Fungus-induced PF10917.8 KFM78013.1 - 0.047 14.0 0.8 0.047 14.0 0.8 1.7 1 1 1 2 2 2 0 Fungus-induced protein DUF4044 PF13253.6 KFM78013.1 - 0.11 12.0 4.8 0.22 11.1 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Nop PF01798.18 KFM78015.1 - 7.6e-84 280.8 0.9 7.6e-84 280.8 0.9 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFM78015.1 - 7.4e-17 61.5 2.8 7.4e-17 61.5 2.8 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain NUMOD1 PF07453.13 KFM78015.1 - 3.1 8.2 6.8 6 7.2 0.1 3.4 4 0 0 4 4 4 0 NUMOD1 domain zf-GRF PF06839.12 KFM78016.1 - 3.3e-40 135.9 8.9 1e-19 70.3 1.3 2.6 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC_2 PF13696.6 KFM78016.1 - 0.017 15.0 3.7 0.017 15.0 3.7 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFM78016.1 - 0.035 13.8 0.6 0.071 12.8 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KFM78016.1 - 1.1 9.1 8.4 0.12 12.1 3.1 2.2 2 0 0 2 2 2 0 C2H2 zinc-finger RVT_1 PF00078.27 KFM78019.1 - 5.5e-06 26.1 0.1 7.7e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 KFM78020.1 - 1e-89 291.3 95.4 4.3e-09 36.4 0.4 13.2 13 0 0 13 13 13 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78020.1 - 1.5e-61 201.5 111.5 1.8e-06 28.1 1.3 12.2 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78020.1 - 4.6e-42 139.0 104.0 0.0009 19.9 1.0 12.3 12 0 0 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM78020.1 - 1.8e-25 88.5 115.9 0.0008 19.7 1.3 13.2 13 1 0 13 13 12 12 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM78020.1 - 2.2e-17 62.6 102.8 0.02 14.9 2.6 12.9 12 0 0 12 12 12 12 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM78020.1 - 7.1e-16 57.6 72.2 0.048 13.4 0.5 12.5 12 0 0 12 12 12 9 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM78020.1 - 3.1e-11 43.3 91.0 0.27 11.6 0.3 13.1 11 2 1 12 12 12 9 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM78020.1 - 3.1e-07 30.3 42.7 0.047 13.7 0.2 7.5 2 2 5 8 8 8 6 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM78020.1 - 1.3e-06 28.4 17.9 1.6 8.9 0.0 6.0 1 1 5 6 6 6 3 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF2256 PF10013.9 KFM78020.1 - 2e-05 24.6 45.9 10 6.3 0.0 12.0 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.18 KFM78020.1 - 4e-05 23.8 26.3 1.7 9.0 1.0 7.4 1 1 8 9 9 9 2 BolA-like protein FYVE PF01363.21 KFM78020.1 - 6.3e-05 23.0 73.5 0.018 15.1 10.2 6.3 1 1 4 5 5 5 3 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 KFM78020.1 - 0.00014 21.8 51.8 2.7 8.1 0.1 11.6 7 3 5 12 12 12 3 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM78020.1 - 0.00078 19.3 56.5 3.9 7.5 0.1 12.6 11 1 1 12 12 12 3 zinc-finger of a C2HC-type TRAF6_Z2 PF18048.1 KFM78020.1 - 0.013 15.6 66.9 0.63 10.2 0.7 12.3 12 1 0 12 12 12 0 TNF receptor-associated factor 6 zinc finger 2 BHD_1 PF10403.9 KFM78020.1 - 0.019 14.8 7.2 3.6 7.5 0.0 5.2 6 1 0 6 6 6 0 Rad4 beta-hairpin domain 1 zf-HIT PF04438.16 KFM78020.1 - 0.063 13.2 75.3 0.26 11.2 1.0 12.1 12 0 0 12 12 12 0 HIT zinc finger Mga PF05043.13 KFM78020.1 - 0.53 10.9 2.6 4.1 8.1 0.1 3.3 3 0 0 3 3 3 0 Mga helix-turn-helix domain zf-CHCC PF10276.9 KFM78020.1 - 1.4 9.0 24.4 57 3.9 0.0 9.6 12 0 0 12 12 11 0 Zinc-finger domain DUF952 PF06108.12 KFM78020.1 - 1.5 8.8 7.8 58 3.8 0.2 4.7 3 3 3 6 6 6 0 Protein of unknown function (DUF952) zinc_ribbon_15 PF17032.5 KFM78020.1 - 2.1 9.1 57.4 3 8.7 2.8 6.6 2 1 3 7 7 7 0 zinc-ribbon family GAGA PF09237.11 KFM78020.1 - 3.3 7.6 24.5 2.7 7.9 0.2 7.1 4 4 5 9 9 9 0 GAGA factor I-set PF07679.16 KFM78021.1 - 9.5e-49 163.4 1.8 5.3e-16 58.5 0.0 5.2 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM78021.1 - 2.5e-33 114.5 1.7 5.1e-12 46.2 0.0 5.1 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 KFM78021.1 - 1.9e-19 69.8 3.3 6.6e-07 29.6 0.0 4.8 5 0 0 5 5 5 3 Fibronectin type III domain Ig_2 PF13895.6 KFM78021.1 - 1.3e-16 60.7 1.2 2.4e-07 31.0 0.1 4.5 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFM78021.1 - 3.4e-11 43.2 8.0 0.012 15.8 0.0 5.6 5 0 0 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.12 KFM78021.1 - 0.00041 20.4 3.0 0.76 9.9 0.0 4.8 4 1 0 4 4 4 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM78021.1 - 0.0039 17.3 5.6 18 5.6 0.1 5.8 4 2 1 5 5 5 1 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFM78021.1 - 0.012 16.2 0.0 13 6.5 0.1 3.2 1 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Serine_rich PF08824.10 KFM78021.1 - 0.015 15.3 0.5 0.041 13.9 0.5 1.7 1 0 0 1 1 1 0 Serine rich protein interaction domain CENP-Q PF13094.6 KFM78021.1 - 0.51 10.5 9.9 0.089 13.0 3.8 2.6 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit fn3 PF00041.21 KFM78022.1 - 6.4e-73 241.2 9.3 1.7e-16 60.4 0.2 6.5 6 0 0 6 6 6 5 Fibronectin type III domain I-set PF07679.16 KFM78022.1 - 7.5e-38 128.5 1.1 1.6e-17 63.4 0.0 4.3 5 0 0 5 5 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM78022.1 - 3.3e-26 91.7 4.9 4.7e-14 52.7 0.5 4.2 4 0 0 4 4 4 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM78022.1 - 3.5e-23 82.0 0.2 8.1e-07 29.5 0.0 6.4 6 0 0 6 6 6 4 Purple acid Phosphatase, N-terminal domain ig PF00047.25 KFM78022.1 - 3.9e-17 62.2 5.1 2e-10 40.7 0.4 3.0 3 0 0 3 3 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM78022.1 - 4.8e-17 62.1 0.6 7.9e-09 35.7 0.2 2.6 2 0 0 2 2 2 2 Immunoglobulin domain fn3_4 PF16794.5 KFM78022.1 - 3.4e-09 36.5 0.0 0.057 13.3 0.0 5.9 5 1 0 5 5 5 1 Fibronectin-III type domain V-set PF07686.17 KFM78022.1 - 2.5e-08 34.0 2.3 0.0016 18.6 0.0 4.2 3 1 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM78022.1 - 7.9e-07 29.1 1.0 0.02 14.9 0.1 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain DUF2369 PF10179.9 KFM78022.1 - 1.3e-05 25.5 0.0 0.078 13.4 0.0 4.8 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2369) Ig_C17orf99 PF17736.1 KFM78022.1 - 2.7e-05 24.1 0.1 0.00024 21.1 0.1 2.3 2 0 0 2 2 2 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFM78022.1 - 9.9e-05 22.5 0.3 0.0088 16.2 0.0 3.0 3 0 0 3 3 2 1 Natural killer cell receptor 2B4 PhoD_N PF16655.5 KFM78022.1 - 0.00012 22.6 0.7 0.62 10.6 0.0 4.6 5 0 0 5 5 4 1 PhoD-like phosphatase, N-terminal domain SusE PF14292.6 KFM78022.1 - 0.00047 20.4 0.3 5.2 7.3 0.0 4.0 4 0 0 4 4 3 2 SusE outer membrane protein C1-set PF07654.15 KFM78022.1 - 0.0045 17.3 0.4 0.15 12.5 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin C1-set domain V-set_CD47 PF08204.11 KFM78022.1 - 0.0099 15.9 0.4 0.046 13.7 0.1 2.2 2 0 0 2 2 2 1 CD47 immunoglobulin-like domain Glyco_hydro_36C PF16874.5 KFM78022.1 - 0.022 15.2 0.0 9.5 6.8 0.0 2.8 3 0 0 3 3 2 0 Glycosyl hydrolase family 36 C-terminal domain Izumo-Ig PF16706.5 KFM78022.1 - 0.029 14.4 1.0 2.7 8.1 0.0 3.3 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Reeler PF02014.16 KFM78022.1 - 0.034 14.9 0.5 24 5.7 0.0 4.2 4 1 0 4 4 4 0 Reeler domain Ig_4 PF16680.5 KFM78022.1 - 0.071 13.4 0.2 0.79 10.0 0.1 2.7 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain bMG6 PF17962.1 KFM78022.1 - 0.11 12.6 0.8 20 5.4 0.0 3.6 4 0 0 4 4 4 0 Bacterial macroglobulin domain 6 Invasin_D3 PF09134.10 KFM78022.1 - 0.69 10.3 3.3 4.3 7.7 0.3 2.6 2 0 0 2 2 2 0 Invasin, domain 3 7tm_1 PF00001.21 KFM78023.1 - 2e-12 47.0 1.7 2.4e-12 46.7 1.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM78023.1 - 1.5e-05 24.5 0.5 1.9e-05 24.2 0.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2678 PF10856.8 KFM78023.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) LRR_8 PF13855.6 KFM78024.1 - 1.3e-46 156.2 55.2 2.7e-11 43.0 1.2 5.4 3 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFM78024.1 - 2.1e-21 75.6 38.6 7e-05 23.1 1.0 6.0 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM78024.1 - 5.3e-12 45.8 0.0 2.5e-06 27.5 0.0 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM78024.1 - 2.2e-09 36.5 34.0 3.2 8.6 0.1 10.1 10 1 0 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.6 KFM78024.1 - 1.4e-06 28.0 9.9 0.0023 17.5 0.7 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRRCT PF01463.24 KFM78024.1 - 0.05 14.2 0.1 2.4 8.9 0.0 3.1 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain TPKR_C2 PF16920.5 KFM78024.1 - 0.094 12.9 10.6 0.18 12.0 0.5 3.8 4 1 1 5 5 5 0 Tyrosine-protein kinase receptor C2 Ig-like domain WD40 PF00400.32 KFM78026.1 - 0.057 14.3 0.2 0.09 13.7 0.2 1.5 1 1 0 1 1 1 0 WD domain, G-beta repeat ACOX PF01756.19 KFM78028.1 - 1.6e-49 167.9 0.0 3.2e-49 166.9 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KFM78028.1 - 1.3e-16 60.6 0.0 2.1e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFM78028.1 - 2.9e-08 34.1 0.0 5.5e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KFM78028.1 - 0.045 14.3 0.7 0.083 13.4 0.7 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFM78029.1 - 1.9e-16 60.1 0.0 3.2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFM78029.1 - 0.0017 18.6 0.1 0.0066 16.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 KFM78030.1 - 3.9e-17 62.4 0.0 4.6e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA oxidase IPK PF03770.16 KFM78031.1 - 2.9e-25 89.3 0.1 4.1e-25 88.8 0.1 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase PRKCSH-like PF12999.7 KFM78032.1 - 3.7e-31 108.2 6.6 5.1e-31 107.8 6.6 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 KFM78032.1 - 0.0056 16.9 16.1 0.33 11.2 5.0 2.6 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A Nckap1 PF09735.9 KFM78033.1 - 2.2e-104 350.5 0.1 2.4e-104 350.4 0.1 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Nckap1 PF09735.9 KFM78034.1 - 6.1e-143 478.2 2.0 7.4e-143 477.9 2.0 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Nckap1 PF09735.9 KFM78035.1 - 2.6e-225 751.0 5.6 3.2e-225 750.7 5.6 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein CAAP1 PF15335.6 KFM78036.1 - 0.08 13.5 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 LAP1C PF05609.12 KFM78038.1 - 2.4e-21 76.4 0.1 3e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Homeodomain PF00046.29 KFM78039.1 - 1.5e-22 79.2 8.9 2.4e-22 78.5 8.9 1.4 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFM78039.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) PAS_9 PF13426.7 KFM78040.1 - 3.3e-11 43.3 0.0 7.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KFM78040.1 - 9.4e-07 28.8 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFM78040.1 - 1.1e-06 28.8 0.0 2.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KFM78040.1 - 2.8e-05 24.0 0.0 6.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KFM78040.1 - 0.00014 22.1 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_12 PF18095.1 KFM78040.1 - 0.0045 16.6 0.0 0.0099 15.5 0.0 1.6 1 0 0 1 1 1 1 UPF0242 C-terminal PAS-like domain PDEase_I PF00233.19 KFM78041.1 - 6.2e-75 252.0 0.8 7.9e-75 251.6 0.8 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase LmjF365940-deam PF14421.6 KFM78041.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases I-set PF07679.16 KFM78043.1 - 3.8e-84 276.9 0.3 2e-15 56.6 0.0 6.8 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM78043.1 - 3.8e-84 277.3 10.2 9.2e-15 55.0 0.0 7.2 7 0 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFM78043.1 - 2.1e-59 197.8 3.2 2.2e-12 47.1 0.0 6.9 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 KFM78043.1 - 1.1e-57 192.1 0.3 3.2e-11 43.2 0.0 6.7 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 KFM78043.1 - 1.3e-25 89.7 14.0 0.0023 18.1 0.0 10.8 6 5 1 7 7 7 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM78043.1 - 3.9e-22 78.1 0.5 0.00046 20.2 0.0 6.4 6 0 0 6 6 6 6 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM78043.1 - 2.2e-17 63.2 0.5 0.0057 17.0 0.0 6.2 6 1 0 6 6 6 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM78043.1 - 2.4e-11 43.7 0.0 0.25 11.6 0.0 5.9 5 0 0 5 5 5 3 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM78043.1 - 7e-11 42.0 0.2 0.59 10.2 0.0 5.5 5 0 0 5 5 5 3 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFM78043.1 - 1.4e-09 38.2 0.2 0.0038 17.6 0.0 5.5 6 0 0 6 6 5 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFM78043.1 - 2.6e-09 36.5 0.1 0.02 14.5 0.1 4.8 5 0 0 5 5 5 3 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM78043.1 - 2.7e-06 27.3 0.0 0.037 14.0 0.0 5.4 6 1 0 6 6 6 1 C17orf99 Ig domain MBG_2 PF18676.1 KFM78043.1 - 0.022 15.4 1.7 0.87 10.3 0.1 3.1 3 1 0 3 3 2 0 MBG domain (YGX type) V-set_CD47 PF08204.11 KFM78043.1 - 5.3 7.0 7.4 4.6 7.2 1.2 3.8 5 1 0 5 5 5 0 CD47 immunoglobulin-like domain URO-D PF01208.17 KFM78044.1 - 9e-130 432.8 0.0 1e-129 432.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) TRAM_LAG1_CLN8 PF03798.16 KFM78045.1 - 2.9e-07 30.4 8.8 2.9e-07 30.4 8.8 2.0 2 0 0 2 2 2 1 TLC domain Homeodomain PF00046.29 KFM78045.1 - 0.00062 19.6 2.0 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 1 Homeodomain YdaS_antitoxin PF15943.5 KFM78045.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT TRAM1 PF08390.11 KFM78045.1 - 0.013 15.1 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 TRAM1-like protein HTH_23 PF13384.6 KFM78045.1 - 0.07 12.9 0.9 0.13 12.1 0.9 1.4 1 0 0 1 1 1 0 Homeodomain-like domain TRAM_LAG1_CLN8 PF03798.16 KFM78046.1 - 3.4e-12 46.5 8.6 3.9e-12 46.3 8.6 1.0 1 0 0 1 1 1 1 TLC domain Bax1-I PF01027.20 KFM78047.1 - 0.00025 21.0 1.8 0.0003 20.7 1.8 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 GM_CSF PF01109.17 KFM78048.1 - 0.00097 19.3 0.2 0.002 18.2 0.2 1.6 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor ArdA PF07275.11 KFM78048.1 - 0.076 13.6 1.0 0.22 12.1 1.1 1.8 1 1 0 1 1 1 0 Antirestriction protein (ArdA) EPOP PF15223.6 KFM78048.1 - 0.23 10.8 4.9 0.3 10.4 4.9 1.1 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein Tup_N PF08581.10 KFM78049.1 - 0.002 18.4 8.2 0.002 18.4 8.2 10.9 6 4 6 12 12 12 2 Tup N-terminal ATG16 PF08614.11 KFM78049.1 - 0.006 16.8 10.5 0.006 16.8 10.5 8.6 2 1 2 5 5 5 1 Autophagy protein 16 (ATG16) Methyltransf_25 PF13649.6 KFM78049.1 - 0.075 13.8 0.0 0.7 10.6 0.0 2.8 1 0 0 1 1 1 0 Methyltransferase domain LRR_8 PF13855.6 KFM78050.1 - 2.4e-08 33.6 6.4 7.1e-08 32.1 6.3 1.9 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KFM78050.1 - 2.5e-07 30.9 9.8 0.00013 22.2 1.6 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) ZZ PF00569.17 KFM78050.1 - 0.054 13.3 0.4 0.17 11.7 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, ZZ type LRR_1 PF00560.33 KFM78050.1 - 0.5 11.1 7.5 5.4 8.0 0.1 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat DUF4371 PF14291.6 KFM78051.1 - 2.3e-05 24.2 0.2 9.9e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM78051.1 - 0.00086 18.8 1.6 0.0017 17.9 1.2 1.7 1 1 0 1 1 1 1 Zinc-finger C2H2-type Guanylate_cyc PF00211.20 KFM78055.1 - 2.9e-11 43.3 0.1 3.2e-11 43.2 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SQS_PSY PF00494.19 KFM78057.1 - 2e-17 63.6 0.0 2.9e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase HTH_Tnp_Tc3_1 PF11427.8 KFM78057.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Tc3 transposase ATP_transf PF09830.9 KFM78060.1 - 0.12 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP adenylyltransferase 7tm_1 PF00001.21 KFM78062.1 - 3.5e-06 26.6 2.4 4.2e-06 26.3 2.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) F_actin_cap_B PF01115.17 KFM78062.1 - 0.16 11.6 0.4 0.2 11.2 0.4 1.1 1 0 0 1 1 1 0 F-actin capping protein, beta subunit MOZ_SAS PF01853.18 KFM78063.1 - 5.1e-82 273.9 0.1 7.4e-82 273.3 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFM78063.1 - 7.1e-24 83.2 4.5 7.1e-24 83.2 4.5 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 KFM78063.1 - 7.4e-13 48.2 0.2 2.3e-12 46.6 0.2 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KFM78063.1 - 0.02 15.3 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nucleoporin_FG2 PF15967.5 KFM78064.1 - 4.8e-84 283.0 26.0 7.4e-84 282.4 26.0 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeated region L31 PF09784.9 KFM78064.1 - 0.13 12.6 0.9 0.56 10.7 0.3 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 YPEB PF14620.6 KFM78064.1 - 0.16 11.3 11.5 1.2 8.4 6.3 2.2 1 1 0 2 2 2 0 YpeB sporulation DUF4830 PF16112.5 KFM78064.1 - 0.32 11.5 1.2 0.39 11.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4830) DUF1664 PF07889.12 KFM78064.1 - 0.73 9.9 8.4 6.5 6.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.18 KFM78064.1 - 0.91 9.6 3.5 2 8.6 3.5 1.6 1 1 0 1 1 1 0 Cobalamin adenosyltransferase FlxA PF14282.6 KFM78064.1 - 1.2 9.2 15.5 0.24 11.4 1.3 3.2 2 1 0 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 KFM78064.1 - 3.9 7.7 15.7 7.6 6.7 5.0 2.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-18_N PF10496.9 KFM78064.1 - 4.3 7.7 8.1 94 3.4 8.1 2.4 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Exonuc_VII_L PF02601.15 KFM78064.1 - 7.4 6.0 16.0 39 3.7 16.0 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF719 PF05334.13 KFM78065.1 - 8.8e-58 195.6 2.2 8.8e-58 195.6 2.2 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF719) zf-C2H2_jaz PF12171.8 KFM78066.1 - 3.8e-07 30.2 1.5 6.3e-07 29.5 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM78066.1 - 1.3e-06 28.5 1.4 2e-06 28.0 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 KFM78066.1 - 0.00023 20.9 1.4 0.00047 19.9 1.4 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2 PF00096.26 KFM78066.1 - 0.079 13.4 0.7 0.16 12.5 0.6 1.6 1 1 0 1 1 1 0 Zinc finger, C2H2 type TMEM154 PF15102.6 KFM78067.1 - 0.011 15.7 0.7 0.029 14.3 0.7 1.7 1 1 0 1 1 1 0 TMEM154 protein family SIT PF15330.6 KFM78067.1 - 0.2 12.1 0.1 0.21 12.0 0.1 1.3 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Insulin_TMD PF17870.1 KFM78067.1 - 0.23 11.6 2.9 0.7 10.0 2.9 1.8 1 1 0 1 1 1 0 Insulin receptor trans-membrane segment fn3 PF00041.21 KFM78068.1 - 6.8e-14 52.0 0.1 7.9e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Fibronectin type III domain fn3_2 PF16893.5 KFM78068.1 - 0.047 13.9 0.0 0.081 13.1 0.0 1.4 1 1 0 1 1 1 0 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM78068.1 - 0.076 13.6 0.1 0.26 11.9 0.1 1.8 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Adeno_VII PF03228.14 KFM78070.1 - 0.061 14.0 0.0 0.068 13.8 0.0 1.0 1 0 0 1 1 1 0 Adenoviral core protein VII RNase_T PF00929.24 KFM78071.1 - 6.2e-25 88.7 0.1 3e-24 86.4 0.0 2.0 2 0 0 2 2 2 1 Exonuclease TackOD1 PF18551.1 KFM78071.1 - 0.0073 16.0 0.2 0.0073 16.0 0.2 2.5 2 1 1 3 3 3 1 Thaumarchaeal output domain 1 CABIT PF12736.7 KFM78072.1 - 2.5e-44 151.7 0.7 3.9e-44 151.0 0.1 1.7 2 0 0 2 2 2 1 Cell-cycle sustaining, positive selection, Integrase_H2C2 PF17921.1 KFM78074.1 - 4e-05 23.6 0.1 9e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain LRR_8 PF13855.6 KFM78076.1 - 2e-18 65.9 1.5 1.5e-08 34.3 0.4 4.5 2 2 3 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 KFM78076.1 - 8e-13 48.5 4.0 4.9e-10 39.5 1.7 2.2 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM78076.1 - 3.5e-05 24.1 7.0 0.0017 18.7 0.1 5.3 6 1 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM78076.1 - 0.011 16.2 1.8 3 8.7 0.4 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat YfkD PF14167.6 KFM78076.1 - 0.1 11.8 0.0 5.1 6.2 0.0 2.1 2 0 0 2 2 2 0 YfkD-like protein ASC PF00858.24 KFM78077.1 - 5.3e-50 170.7 4.8 6.3e-50 170.4 4.8 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 KFM78078.1 - 6.9e-30 104.4 1.5 7.6e-30 104.2 1.5 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Myosin_tail_1 PF01576.19 KFM78079.1 - 0.00026 19.0 5.4 0.00033 18.6 5.4 1.1 1 0 0 1 1 1 1 Myosin tail EzrA PF06160.12 KFM78079.1 - 0.00036 18.8 7.3 0.00056 18.2 7.3 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 KFM78079.1 - 0.0029 18.0 5.0 0.058 13.9 0.7 2.6 1 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein SesA PF17107.5 KFM78079.1 - 0.0068 16.6 1.1 1.8 8.8 0.5 2.3 1 1 1 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases Rab5-bind PF09311.11 KFM78079.1 - 0.01 15.2 6.0 0.019 14.4 6.0 1.5 1 0 0 1 1 1 0 Rabaptin-like protein Spectrin PF00435.21 KFM78079.1 - 0.011 16.2 4.6 0.014 15.9 3.0 2.0 2 1 1 3 3 2 0 Spectrin repeat UPF0242 PF06785.11 KFM78079.1 - 0.011 15.8 5.1 0.018 15.2 5.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 KFM78079.1 - 0.014 14.7 8.9 0.02 14.2 6.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF848 PF05852.11 KFM78079.1 - 0.014 15.5 4.0 0.025 14.7 3.8 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Apolipoprotein PF01442.18 KFM78079.1 - 0.02 14.8 1.5 0.039 13.8 1.5 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Laminin_II PF06009.12 KFM78079.1 - 0.024 14.7 8.9 1.6 8.8 0.3 2.3 1 1 1 2 2 2 0 Laminin Domain II Yuri_gagarin PF15934.5 KFM78079.1 - 0.033 14.1 4.4 0.047 13.5 4.4 1.2 1 0 0 1 1 1 0 Yuri gagarin DUF445 PF04286.12 KFM78079.1 - 0.035 13.9 1.7 0.044 13.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Lebercilin PF15619.6 KFM78079.1 - 0.035 13.8 6.9 0.2 11.3 4.2 2.1 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 KFM78079.1 - 0.036 14.1 3.7 0.16 12.1 3.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 KFM78079.1 - 0.043 12.8 10.5 0.063 12.2 10.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF724 PF05266.14 KFM78079.1 - 0.044 13.6 6.5 0.066 13.0 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 KFM78079.1 - 0.051 13.6 6.7 0.43 10.6 0.5 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3416 PF11896.8 KFM78079.1 - 0.062 13.6 0.2 0.097 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) TACC_C PF05010.14 KFM78079.1 - 0.064 13.0 8.0 0.13 12.1 8.0 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal KxDL PF10241.9 KFM78079.1 - 0.089 13.1 6.1 1.2 9.5 2.6 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 KFM78079.1 - 0.1 12.6 7.7 3.8 7.6 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ZYG-11_interact PF05884.12 KFM78079.1 - 0.1 12.0 1.4 0.16 11.4 1.4 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Phage_GPO PF05929.11 KFM78079.1 - 0.19 11.4 4.4 0.3 10.7 4.4 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DegS PF05384.11 KFM78079.1 - 0.19 11.2 7.1 0.94 8.9 2.2 2.9 1 1 2 3 3 3 0 Sensor protein DegS KELK PF15796.5 KFM78079.1 - 0.22 12.0 3.6 4.2 7.9 0.0 2.7 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4164 PF13747.6 KFM78079.1 - 0.51 10.7 4.4 10 6.5 3.3 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Cluap1 PF10234.9 KFM78079.1 - 0.53 9.6 9.8 4.2 6.7 0.6 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 TPR_MLP1_2 PF07926.12 KFM78079.1 - 0.53 10.4 9.5 0.34 11.0 4.3 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Mod_r PF07200.13 KFM78079.1 - 0.56 10.3 8.2 0.29 11.2 4.2 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LXG PF04740.12 KFM78079.1 - 0.73 9.5 12.8 0.99 9.1 7.1 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily PRKG1_interact PF15898.5 KFM78079.1 - 0.76 10.7 7.0 2.6 9.0 2.6 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Mit_KHE1 PF10173.9 KFM78079.1 - 1.2 9.2 8.3 1 9.4 7.1 1.5 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF745 PF05335.13 KFM78079.1 - 1.2 8.8 5.6 2.7 7.7 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF745) SYF2 PF08231.12 KFM78079.1 - 1.3 9.4 11.4 1.2 9.5 10.3 1.7 1 1 0 1 1 1 0 SYF2 splicing factor LMBR1 PF04791.16 KFM78079.1 - 1.5 7.7 5.8 1.7 7.4 5.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Plk4_PB2 PF18409.1 KFM78079.1 - 1.6 9.4 8.4 5.5 7.7 3.1 2.7 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 DUF148 PF02520.17 KFM78079.1 - 1.7 8.8 8.4 2.8 8.1 4.7 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF148 Prefoldin_2 PF01920.20 KFM78079.1 - 1.7 8.7 6.7 3.9 7.5 5.0 2.5 1 1 1 2 2 2 0 Prefoldin subunit HIP1_clath_bdg PF16515.5 KFM78079.1 - 1.9 9.2 7.3 3.2 8.4 5.8 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fib_alpha PF08702.10 KFM78079.1 - 2 8.6 12.3 2.1 8.5 8.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 KFM78079.1 - 2.1 7.5 12.8 0.67 9.1 5.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein HR1 PF02185.16 KFM78079.1 - 2.9 8.1 6.2 3.8 7.7 1.7 2.9 2 2 1 3 3 3 0 Hr1 repeat DUF948 PF06103.11 KFM78079.1 - 3.2 8.1 4.5 30 5.0 1.1 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2408 PF10303.9 KFM78079.1 - 9.5 6.8 9.7 0.55 10.8 4.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) Cyt-b5 PF00173.28 KFM78081.1 - 2.3e-21 75.7 0.0 2.9e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ERCC3_RAD25_C PF16203.5 KFM78081.1 - 0.17 11.0 0.0 15 4.7 0.0 2.0 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase RRM_1 PF00076.22 KFM78083.1 - 1.7e-20 72.6 0.1 1.6e-05 24.7 0.0 5.2 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFM78083.1 - 0.00096 19.4 0.8 2.9 8.1 0.0 4.3 4 1 1 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter TPR_12 PF13424.6 KFM78085.1 - 0.02 15.2 1.0 0.12 12.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4279 PF14106.6 KFM78085.1 - 0.044 14.0 0.2 0.8 9.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) TPR_1 PF00515.28 KFM78085.1 - 0.35 10.8 1.9 0.53 10.2 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM78085.1 - 0.69 10.2 2.6 0.98 9.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 KFM78088.1 - 1.6e-24 84.9 46.0 7.3e-06 26.2 3.3 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM78088.1 - 4.8e-23 80.5 34.1 6e-06 26.4 0.8 6.8 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM78088.1 - 1.7e-17 62.6 39.3 0.0017 19.0 1.9 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM78088.1 - 1.4e-11 44.1 35.3 0.00023 21.1 1.8 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM78088.1 - 1.4e-05 25.2 28.3 0.069 13.5 1.5 5.9 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 KFM78088.1 - 0.00011 22.2 21.7 0.1 12.8 0.9 5.8 5 0 0 5 5 5 1 AN1-like Zinc finger C1_4 PF07975.12 KFM78088.1 - 0.0005 20.2 19.8 0.16 12.2 2.1 4.1 1 1 3 4 4 4 2 TFIIH C1-like domain GAGA PF09237.11 KFM78088.1 - 0.0018 18.0 14.0 0.18 11.6 0.4 4.5 1 1 3 4 4 4 2 GAGA factor Zn-ribbon_8 PF09723.10 KFM78088.1 - 0.0024 18.0 25.4 0.048 13.8 3.4 4.5 5 0 0 5 5 4 2 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFM78088.1 - 0.013 15.4 1.3 0.013 15.4 1.3 4.6 5 0 0 5 5 5 0 zinc-finger of a C2HC-type DZR PF12773.7 KFM78088.1 - 0.015 15.3 17.2 6.1e+02 0.6 17.2 3.8 1 1 0 1 1 1 0 Double zinc ribbon Rad50_zn_hook PF04423.14 KFM78088.1 - 0.017 14.9 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-met PF12874.7 KFM78088.1 - 0.019 15.3 30.7 0.087 13.3 0.5 5.6 6 0 0 6 6 5 0 Zinc-finger of C2H2 type XPA_N PF01286.18 KFM78088.1 - 0.02 14.9 14.7 1.3 9.2 0.7 5.2 5 0 0 5 5 5 0 XPA protein N-terminal zf-C2HE PF16278.5 KFM78088.1 - 0.035 14.5 28.7 0.046 14.2 1.2 5.6 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 KFM78088.1 - 0.89 9.4 3.2 3.9 7.4 0.1 2.9 3 0 0 3 3 2 0 C2H2 type zinc-finger (1 copy) YhfH PF14149.6 KFM78088.1 - 1.1 9.2 8.8 25 4.9 0.0 3.7 3 0 0 3 3 3 0 YhfH-like protein FYVE PF01363.21 KFM78088.1 - 1.8 8.8 26.2 0.9 9.7 5.3 3.7 1 1 2 3 3 3 0 FYVE zinc finger DUF2256 PF10013.9 KFM78088.1 - 3.3 7.9 17.4 1.1 9.5 0.1 4.8 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3268 PF11672.8 KFM78088.1 - 3.6 7.9 9.4 8.8 6.7 0.3 2.7 2 1 1 3 3 3 0 zinc-finger-containing domain zinc_ribbon_15 PF17032.5 KFM78088.1 - 3.7 8.4 17.7 24 5.8 6.3 3.8 1 1 3 4 4 3 0 zinc-ribbon family Prok-RING_1 PF14446.6 KFM78088.1 - 4 7.4 16.9 3.8 7.5 2.3 4.9 4 1 0 4 4 4 0 Prokaryotic RING finger family 1 CpXC PF14353.6 KFM78088.1 - 4.3 7.4 17.7 2 8.5 0.2 4.3 1 1 4 5 5 5 0 CpXC protein zf-CHCC PF10276.9 KFM78088.1 - 6.7 6.9 13.2 5.4 7.2 0.7 3.8 4 0 0 4 4 4 0 Zinc-finger domain zinc-ribbons_6 PF07191.12 KFM78088.1 - 7.6 6.6 18.1 4.9 7.2 1.6 4.0 2 1 1 3 3 3 0 zinc-ribbons TRAF6_Z2 PF18048.1 KFM78088.1 - 9.5 6.4 13.7 0.24 11.5 0.9 3.8 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 Bap31_Bap29_C PF18035.1 KFM78089.1 - 0.024 14.6 2.1 0.024 14.6 2.1 1.6 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain MULE PF10551.9 KFM78090.1 - 1.8e-15 57.2 0.3 2.9e-15 56.4 0.3 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF3535 PF12054.8 KFM78090.1 - 0.041 13.1 0.1 0.052 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Transposase_mut PF00872.18 KFM78090.1 - 0.054 12.3 0.1 0.064 12.1 0.1 1.1 1 0 0 1 1 1 0 Transposase, Mutator family Roc PF08477.13 KFM78091.1 - 0.039 14.2 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM78091.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Ras family TniB PF05621.11 KFM78091.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KFM78091.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KFM78091.1 - 0.22 10.9 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit HTH_Tnp_Tc3_2 PF01498.18 KFM78092.1 - 2.3e-16 59.8 2.2 5.1e-16 58.7 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM78092.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Chromo_shadow PF01393.19 KFM78093.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Chromo shadow domain Calx-beta PF03160.14 KFM78096.1 - 2.3e-22 79.0 0.0 7.2e-18 64.6 0.0 2.7 2 0 0 2 2 2 2 Calx-beta domain Sugar_tr PF00083.24 KFM78098.1 - 2.6e-06 26.6 0.0 2.6e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 KFM78099.1 - 1.1e-07 31.1 6.1 1.6e-07 30.6 6.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM78099.1 - 9.1e-05 21.5 11.7 0.00018 20.6 12.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Wzy_C PF04932.15 KFM78099.1 - 0.033 13.8 1.3 0.14 11.8 0.0 2.4 3 0 0 3 3 3 0 O-Antigen ligase DUF5373 PF17343.2 KFM78099.1 - 0.034 14.0 0.7 0.042 13.7 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5373) MerC PF03203.14 KFM78099.1 - 0.057 13.9 1.3 0.21 12.0 0.7 2.3 1 1 0 1 1 1 0 MerC mercury resistance protein DUF2628 PF10947.8 KFM78099.1 - 1.1 9.7 5.5 6.2 7.2 2.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) Sugar_tr PF00083.24 KFM78100.1 - 1.9e-32 112.7 15.8 2.6e-32 112.3 15.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM78100.1 - 3.2e-31 108.5 20.0 1.4e-23 83.4 5.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KFM78100.1 - 0.0016 16.7 0.2 0.0016 16.7 0.2 2.0 2 0 0 2 2 2 1 BT1 family MFS_1 PF07690.16 KFM78101.1 - 2.8e-31 108.7 15.8 1.2e-22 80.3 0.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM78101.1 - 2.6e-30 105.7 16.2 3.8e-30 105.1 16.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KFM78101.1 - 9.7e-06 24.4 6.5 9.7e-06 24.4 6.5 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein BT1 PF03092.16 KFM78101.1 - 0.00086 17.7 0.2 0.00086 17.7 0.2 1.9 2 0 0 2 2 2 1 BT1 family Popeye PF04831.13 KFM78102.1 - 7.7e-37 126.6 0.1 9.5e-37 126.3 0.1 1.1 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 KFM78102.1 - 0.0018 18.3 0.0 0.0046 17.0 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain DUF716 PF04819.12 KFM78102.1 - 0.03 14.0 1.2 0.062 12.9 1.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF716) Ras PF00071.22 KFM78103.1 - 0.0013 18.3 0.0 0.0075 15.9 0.0 1.9 1 1 0 1 1 1 1 Ras family Ycf15 PF10705.9 KFM78103.1 - 0.048 13.8 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Chloroplast protein precursor Ycf15 putative Roc PF08477.13 KFM78104.1 - 8.1e-11 42.2 0.0 8.8e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM78104.1 - 3.6e-07 29.9 0.0 3.9e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFM78104.1 - 4.2e-05 23.6 0.0 4.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFM78104.1 - 9.7e-05 22.8 0.0 0.00011 22.6 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KFM78104.1 - 0.00025 20.5 0.0 0.00029 20.3 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KFM78104.1 - 0.00025 20.5 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family IIGP PF05049.13 KFM78104.1 - 0.00039 19.6 0.1 0.00042 19.5 0.1 1.0 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 KFM78104.1 - 0.00074 19.5 0.0 0.00074 19.5 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KFM78104.1 - 0.002 18.7 0.0 0.002 18.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter Septin PF00735.18 KFM78104.1 - 0.0047 16.3 0.0 0.0047 16.3 0.0 1.1 1 0 0 1 1 1 1 Septin MCM PF00493.23 KFM78104.1 - 0.006 15.7 0.0 0.006 15.7 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain AAA_29 PF13555.6 KFM78104.1 - 0.0084 15.8 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KFM78104.1 - 0.015 15.0 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 KFM78104.1 - 0.016 14.4 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 KFM78104.1 - 0.024 14.6 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 KFM78104.1 - 0.028 14.5 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 Dynamin family AAA_24 PF13479.6 KFM78104.1 - 0.036 13.8 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFM78104.1 - 0.038 13.5 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KFM78104.1 - 0.038 14.4 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KFM78104.1 - 0.043 14.2 0.0 0.043 14.2 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hpr_kinase_C PF07475.12 KFM78104.1 - 0.046 13.2 0.2 0.059 12.9 0.2 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain DUF87 PF01935.17 KFM78104.1 - 0.055 13.6 0.1 0.074 13.1 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain NACHT PF05729.12 KFM78104.1 - 0.065 13.1 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 KFM78104.1 - 0.079 12.1 0.2 1.6 7.8 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 KFM78104.1 - 0.081 12.5 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.6 KFM78104.1 - 0.09 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM78104.1 - 0.15 12.3 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain CKS PF01111.19 KFM78105.1 - 3.7e-34 116.8 1.3 4.2e-34 116.6 1.3 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit INSC_LBD PF16748.5 KFM78107.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Inscuteable LGN-binding domain CH PF00307.31 KFM78108.1 - 2.7e-10 40.4 0.0 4.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM78108.1 - 5.3e-08 32.6 0.2 1.1e-07 31.5 0.1 1.7 1 1 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 KFM78108.1 - 0.0011 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 CH-like domain in sperm protein zf-RING_10 PF16685.5 KFM78108.1 - 0.02 15.0 4.0 0.16 12.2 1.4 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 IQ PF00612.27 KFM78109.1 - 7.8e-132 416.9 362.7 0.00011 21.7 0.8 59.4 61 1 1 62 62 62 52 IQ calmodulin-binding motif DUF5377 PF17347.2 KFM78109.1 - 0.43 11.0 17.0 7.1 7.1 0.2 6.1 7 0 0 7 7 7 0 Family of unknown function (DUF5377) Metallothi_Euk2 PF12809.7 KFM78109.1 - 0.9 9.9 3.9 65 3.9 0.0 3.8 3 0 0 3 3 3 0 Eukaryotic metallothionein SWIB PF02201.18 KFM78110.1 - 1.7e-23 82.3 0.4 3.1e-23 81.5 0.4 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEAD PF00270.29 KFM78111.1 - 1.5e-42 145.4 1.0 3.1e-42 144.3 1.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM78111.1 - 1.7e-29 102.4 0.1 1.7e-28 99.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM78111.1 - 3.2e-05 24.0 0.0 5.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFM78111.1 - 7.7e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM78111.1 - 0.00048 20.5 1.1 0.0015 18.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KFM78111.1 - 0.0082 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Helicase Herpes_UL92 PF03048.14 KFM78111.1 - 0.0092 15.8 1.5 0.018 14.9 1.5 1.5 1 0 0 1 1 1 1 UL92 family UTP25 PF06862.12 KFM78111.1 - 0.02 13.7 0.8 0.34 9.6 0.0 2.3 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 KFM78111.1 - 0.04 13.3 0.3 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit PhoH PF02562.16 KFM78111.1 - 0.047 13.1 1.5 0.11 11.9 1.5 1.7 1 1 0 1 1 1 0 PhoH-like protein tRNA-synt_1b PF00579.25 KFM78111.1 - 0.051 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) TniB PF05621.11 KFM78111.1 - 0.056 12.9 0.6 0.44 9.9 0.1 2.1 2 0 0 2 2 2 0 Bacterial TniB protein UvrD-helicase PF00580.21 KFM78111.1 - 0.11 12.0 0.8 0.16 11.5 0.8 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KFM78111.1 - 0.25 11.6 2.5 1.2 9.4 1.4 2.5 2 1 0 2 2 2 0 AAA domain Chromo PF00385.24 KFM78112.1 - 4.2e-17 61.8 0.1 1.4e-16 60.1 0.1 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-C2H2_4 PF13894.6 KFM78112.1 - 2.1e-13 49.9 121.2 0.0095 16.7 1.3 18.7 18 0 0 18 18 18 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM78112.1 - 5e-06 26.4 4.3 0.00059 19.8 0.1 11.1 12 0 0 12 12 12 3 C2H2-type zinc finger zf-CXXC PF02008.20 KFM78112.1 - 9.2e-06 25.6 13.0 9.2e-06 25.6 13.0 5.5 6 0 0 6 6 6 1 CXXC zinc finger domain zf-C2H2 PF00096.26 KFM78112.1 - 5.4e-05 23.4 1.9 5.4e-05 23.4 1.9 17.7 18 0 0 18 18 18 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM78112.1 - 0.00023 21.5 2.1 0.00023 21.5 2.1 15.3 16 0 0 16 16 16 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM78112.1 - 0.00044 20.5 0.8 0.00044 20.5 0.8 12.3 15 0 0 15 15 15 5 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM78112.1 - 0.049 13.9 0.3 0.049 13.9 0.3 11.6 5 4 6 11 11 11 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 KFM78112.1 - 0.24 11.7 0.0 0.24 11.7 0.0 7.4 8 0 0 8 8 8 0 zinc-ribbon Mtf2_C PF14061.6 KFM78112.1 - 0.25 11.5 0.3 0.61 10.3 0.0 1.8 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Pkinase PF00069.25 KFM78113.1 - 1.5e-75 254.0 0.0 1.7e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM78113.1 - 4.4e-34 117.9 0.0 5.5e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM78113.1 - 2.9e-05 23.2 0.2 0.00026 20.1 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM78113.1 - 0.00019 20.8 0.1 0.0076 15.6 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KFM78113.1 - 0.0067 15.5 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KFM78113.1 - 0.031 14.2 0.1 0.067 13.1 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFM78113.1 - 0.68 9.5 2.1 1.8 8.1 0.1 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase XRCC1_N PF01834.16 KFM78114.1 - 0.019 14.9 1.6 0.032 14.2 1.6 1.4 1 0 0 1 1 1 0 XRCC1 N terminal domain DUF4006 PF13179.6 KFM78116.1 - 0.0076 16.1 0.3 0.011 15.7 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF4006) RELT PF12606.8 KFM78116.1 - 0.0078 15.2 1.6 0.0079 15.2 0.8 1.5 1 1 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 Orf78 PF06024.12 KFM78116.1 - 0.014 15.7 0.5 0.014 15.7 0.5 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Ninjurin PF04923.12 KFM78116.1 - 0.015 15.3 0.3 0.017 15.0 0.3 1.0 1 0 0 1 1 1 0 Ninjurin Sec62 PF03839.16 KFM78116.1 - 0.56 9.7 2.0 0.66 9.4 2.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Lectin_C PF00059.21 KFM78117.1 - 2e-60 202.2 16.1 2.3e-25 89.4 0.7 3.2 3 0 0 3 3 3 3 Lectin C-type domain UL45 PF05473.12 KFM78117.1 - 0.00023 20.9 8.9 0.017 14.8 0.0 4.2 4 1 0 4 4 4 2 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 KFM78117.1 - 0.00052 19.4 2.0 0.8 9.0 0.5 4.0 4 0 0 4 4 4 1 Chordopoxvirus A33R protein Podoplanin PF05808.11 KFM78117.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Podoplanin TcA_RBD PF18518.1 KFM78117.1 - 0.12 12.7 0.0 0.83 9.9 0.0 2.3 2 0 0 2 2 2 0 TcA receptor binding domain Histone PF00125.24 KFM78119.1 - 4.1e-24 85.4 1.2 4.9e-24 85.2 1.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM78119.1 - 3.4e-06 27.2 0.1 3.4e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFM78119.1 - 0.00076 19.9 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFM78119.1 - 0.0088 16.1 1.1 0.011 15.8 1.1 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 KFM78119.1 - 0.064 12.9 1.1 4.3 7.0 0.4 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Ribosomal_L23eN PF03939.13 KFM78119.1 - 1 9.6 12.8 0.2 11.9 6.6 2.4 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain Prefoldin PF02996.17 KFM78120.1 - 1.9e-26 92.3 3.4 2.5e-26 91.9 3.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit PHM7_cyt PF14703.6 KFM78120.1 - 0.0063 16.8 1.5 0.009 16.3 1.5 1.3 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter AAA_6 PF12774.7 KFM78120.1 - 0.026 13.5 0.1 0.055 12.4 0.1 1.7 1 1 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region NPV_P10 PF05531.12 KFM78120.1 - 0.095 13.2 4.0 2.8 8.5 0.5 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_1 PF00515.28 KFM78120.1 - 0.14 12.1 0.2 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM78120.1 - 0.14 12.4 0.1 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.6 KFM78120.1 - 0.87 10.0 7.7 0.28 11.6 0.9 2.6 2 1 1 3 3 3 0 Snapin/Pallidin FliJ PF02050.16 KFM78120.1 - 2.9 8.1 10.9 3 8.1 1.4 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Lig_chan-Glu_bd PF10613.9 KFM78121.1 - 5e-29 100.8 0.0 8.7e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM78121.1 - 9.1e-17 61.2 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 KFM78121.1 - 6.1e-14 52.1 0.4 1.4e-13 50.9 0.2 1.8 2 0 0 2 2 2 1 Ligand-gated ion channel ANF_receptor PF01094.28 KFM78121.1 - 1e-13 51.2 0.0 1.6e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region OGG_N PF07934.12 KFM78122.1 - 3.8e-31 107.7 1.5 5.8e-31 107.1 1.5 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KFM78122.1 - 7.6e-17 61.7 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFM78122.1 - 0.0021 17.8 0.0 0.0067 16.2 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif UPF0449 PF15136.6 KFM78122.1 - 0.13 12.7 0.3 0.24 11.9 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 GST_N PF02798.20 KFM78123.1 - 8.6e-12 45.2 0.4 1.8e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFM78123.1 - 1.8e-09 37.9 0.0 3.2e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFM78123.1 - 3.3e-08 33.6 0.0 5.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFM78123.1 - 3.1e-07 30.6 0.0 6.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFM78123.1 - 1.7e-05 24.9 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFM78123.1 - 0.0021 18.8 0.0 0.013 16.2 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KFM78123.1 - 0.0053 16.7 0.0 0.0088 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SUKH-3 PF14433.6 KFM78124.1 - 0.15 12.5 0.0 0.15 12.5 0.0 1.0 1 0 0 1 1 1 0 SUKH-3 immunity protein Pre-PUA PF17832.1 KFM78128.1 - 0.023 15.4 0.2 0.036 14.7 0.2 1.2 1 0 0 1 1 1 0 Pre-PUA-like domain Hormone_recep PF00104.30 KFM78132.1 - 2.2e-29 102.6 0.2 3.8e-29 101.7 0.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFM78132.1 - 5.6e-27 94.0 11.6 1.2e-26 92.9 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 KFM78132.1 - 0.078 13.3 0.1 0.078 13.3 0.1 2.9 1 1 2 3 3 3 0 C1 domain PLA2_B PF01735.18 KFM78133.1 - 2.3e-09 36.2 0.0 2.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.18 KFM78135.1 - 2.2e-41 141.8 0.0 2.5e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 KFM78135.1 - 0.0043 17.3 0.0 0.0051 17.0 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase C2 PF00168.30 KFM78136.1 - 1.6e-13 50.8 0.0 1.9e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain zf-C2H2 PF00096.26 KFM78137.1 - 3.2e-06 27.3 5.7 0.0079 16.6 1.3 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78137.1 - 0.15 13.0 5.3 2.5 9.2 1.6 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KFM78137.1 - 4.7 7.9 11.2 0.48 11.1 1.6 3.8 3 1 1 4 4 4 0 FOXP coiled-coil domain Zap1_zf2 PF18217.1 KFM78137.1 - 8.8 6.4 6.9 5.7 7.0 0.3 3.1 2 0 0 2 2 2 0 Zap1 zinc finger 2 DUF1265 PF06887.14 KFM78138.1 - 0.085 12.8 1.7 0.55 10.2 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1265) DUF846 PF05832.12 KFM78140.1 - 1.2e-53 180.9 13.8 1.5e-53 180.6 13.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) adh_short PF00106.25 KFM78141.1 - 3.9e-20 72.1 0.1 6.6e-20 71.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM78141.1 - 1.2e-11 44.6 0.0 1.6e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sigma_M_inh PF17453.2 KFM78141.1 - 0.13 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-M inhibitor C2 PF00168.30 KFM78142.1 - 0.00011 22.4 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 C2 domain UIM PF02809.20 KFM78144.1 - 0.077 12.9 12.4 0.043 13.7 6.5 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Chitin_bind_4 PF00379.23 KFM78145.1 - 2.7e-12 47.0 5.3 4.7e-12 46.2 5.3 1.4 1 0 0 1 1 1 1 Insect cuticle protein Phlebovirus_G1 PF07243.11 KFM78148.1 - 0.18 10.1 2.6 0.2 10.0 2.6 1.0 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 MscL PF01741.18 KFM78148.1 - 0.5 10.7 4.8 0.75 10.1 4.8 1.4 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL YlaC PF10777.9 KFM78148.1 - 0.51 10.2 3.8 0.62 9.9 3.8 1.2 1 0 0 1 1 1 0 Inner membrane protein YlaC DUF777 PF05606.11 KFM78150.1 - 0.5 10.1 10.3 0.08 12.7 3.9 2.9 3 1 1 4 4 4 0 Borrelia burgdorferi protein of unknown function (DUF777) Motile_Sperm PF00635.26 KFM78151.1 - 6.3e-30 103.2 0.1 6.3e-30 103.2 0.1 1.6 2 0 0 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 KFM78151.1 - 0.00037 20.6 1.0 0.0013 18.9 0.4 2.1 1 1 1 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin NUDE_C PF04880.13 KFM78151.1 - 0.013 16.0 3.2 0.022 15.3 3.2 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region bZIP_1 PF00170.21 KFM78151.1 - 0.09 12.9 4.3 0.16 12.1 4.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 KFM78151.1 - 0.14 12.9 1.4 0.23 12.1 1.4 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Anillin_N PF16018.5 KFM78152.1 - 0.92 10.2 0.1 0.92 10.2 0.1 3.2 2 2 1 3 3 3 0 Anillin N-terminus Caudo_TAP PF02413.17 KFM78152.1 - 4.8 7.3 9.9 0.36 11.0 3.9 1.9 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK zf-H2C2_2 PF13465.6 KFM78153.1 - 6e-13 48.6 22.1 1.8e-07 31.3 0.7 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78153.1 - 1.3e-07 31.7 10.5 7.2e-06 26.2 0.7 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM78153.1 - 0.00021 21.2 1.9 0.00021 21.2 1.9 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger SET PF00856.28 KFM78153.1 - 0.00037 20.9 0.1 0.00037 20.9 0.1 3.1 2 2 0 2 2 2 1 SET domain zf-C2HE PF16278.5 KFM78153.1 - 0.0012 19.2 12.7 0.024 15.1 0.9 3.7 2 1 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 KFM78153.1 - 0.0026 18.4 0.7 0.0026 18.4 0.7 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-CRD PF17979.1 KFM78153.1 - 2.6 8.1 7.4 2.1 8.5 5.2 2.0 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions BolA PF01722.18 KFM78153.1 - 3.6 7.9 0.0 0.15 12.3 0.4 3.8 4 1 1 5 5 5 0 BolA-like protein ZZ PF00569.17 KFM78153.1 - 4.8 7.1 6.0 8.9 6.2 0.3 3.2 3 0 0 3 3 3 0 Zinc finger, ZZ type BCAS3 PF12490.8 KFM78155.1 - 4.5e-32 111.5 0.0 6.5e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 GDP_Man_Dehyd PF16363.5 KFM78158.1 - 4.6e-160 532.5 0.0 5.2e-160 532.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFM78158.1 - 2.1e-74 250.0 0.0 2.7e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFM78158.1 - 1.3e-06 27.7 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KFM78158.1 - 0.001 18.7 0.0 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KFM78158.1 - 0.014 14.5 0.0 0.048 12.8 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFM78158.1 - 0.068 12.3 0.0 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein BBS2_Mid PF14783.6 KFM78159.1 - 0.035 14.2 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Sigma54_activ_2 PF14532.6 KFM78159.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Reg_prop PF07494.11 KFM78159.1 - 0.68 10.4 4.8 2.8 8.5 0.0 4.3 6 1 0 6 6 6 0 Two component regulator propeller Sugar_tr PF00083.24 KFM78160.1 - 8.1e-110 367.8 26.8 9.4e-110 367.5 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM78160.1 - 3.5e-18 65.7 30.3 4.6e-18 65.3 30.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HTH_Tnp_Tc5 PF03221.16 KFM78161.1 - 7.6e-12 45.1 0.3 1.8e-11 43.9 0.1 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_7 PF02796.15 KFM78161.1 - 8.5e-05 22.5 0.0 0.00022 21.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 KFM78161.1 - 0.003 17.2 0.0 0.0056 16.3 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_psq PF05225.16 KFM78161.1 - 0.0057 16.4 0.0 0.019 14.7 0.0 1.9 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 KFM78161.1 - 0.017 14.9 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KFM78161.1 - 0.076 13.1 0.0 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 KFM78161.1 - 0.13 12.7 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_29 PF13551.6 KFM78161.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix OST-HTH PF12872.7 KFM78168.1 - 0.15 11.9 1.1 0.86 9.5 0.1 2.3 2 1 0 2 2 2 0 OST-HTH/LOTUS domain Ig_3 PF13927.6 KFM78169.1 - 6.1e-05 23.6 0.0 6.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM78169.1 - 6.3e-05 23.0 0.0 6.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFM78169.1 - 0.021 15.2 0.0 0.021 15.2 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Mito_carr PF00153.27 KFM78170.1 - 8.7e-67 221.1 2.8 2.4e-22 78.7 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM78170.1 - 0.0022 17.2 0.4 0.15 11.2 0.2 2.6 2 1 1 3 3 3 2 Gammaproteobacterial serine protease EF_TS PF00889.19 KFM78171.1 - 1.4e-25 90.1 0.1 2.2e-25 89.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor TS HTH_55 PF18622.1 KFM78171.1 - 0.055 13.8 0.2 0.28 11.5 0.0 2.2 3 0 0 3 3 3 0 RctB helix turn helix domain DDE_Tnp_1_7 PF13843.6 KFM78172.1 - 8e-09 35.3 0.2 9.4e-09 35.0 0.2 1.1 1 0 0 1 1 1 1 Transposase IS4 PUA PF01472.20 KFM78173.1 - 5.2e-18 64.8 1.6 5.2e-18 64.8 1.6 2.2 2 0 0 2 2 2 1 PUA domain TruB_C_2 PF16198.5 KFM78173.1 - 7.1e-18 64.5 0.2 1.2e-17 63.8 0.2 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 KFM78173.1 - 0.00041 20.6 0.0 0.0012 19.1 0.0 1.8 2 0 0 2 2 2 1 UPF0113 PUA domain DUF309 PF03745.14 KFM78173.1 - 0.084 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Coilin_N PF15862.5 KFM78173.1 - 0.5 10.2 12.9 0.82 9.5 12.9 1.5 1 0 0 1 1 1 0 Coilin N-terminus RNA_polI_A34 PF08208.11 KFM78173.1 - 2.4 8.2 33.2 3.6 7.6 33.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 KFM78173.1 - 2.9 7.6 18.7 3.8 7.3 18.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VIR_N PF15912.5 KFM78173.1 - 3.2 7.3 13.6 4.4 6.8 13.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal GST_N_3 PF13417.6 KFM78174.1 - 2.4e-08 34.3 0.0 5.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFM78174.1 - 2.4e-05 24.5 0.0 5.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFM78174.1 - 0.00017 21.5 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFM78174.1 - 0.023 15.0 0.0 0.046 14.0 0.0 1.6 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein CaKB PF03185.15 KFM78174.1 - 0.11 12.1 0.7 0.16 11.7 0.7 1.2 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit DAPDH_C PF16654.5 KFM78174.1 - 0.2 11.5 0.1 0.26 11.1 0.1 1.2 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Phostensin_N PF13916.6 KFM78175.1 - 0.056 13.8 7.4 4.3 7.8 0.4 3.6 1 1 1 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal RRP14 PF15459.6 KFM78175.1 - 0.18 12.4 0.2 0.18 12.4 0.2 4.4 6 0 0 6 6 6 0 60S ribosome biogenesis protein Rrp14 Myb_DNA-bind_5 PF13873.6 KFM78177.1 - 3.8e-13 49.3 1.8 7.8e-13 48.3 1.8 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Suppressor_P21 PF11479.8 KFM78177.1 - 0.025 14.8 0.1 0.05 13.8 0.1 1.4 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain ChapFlgA_N PF17656.1 KFM78177.1 - 0.036 14.2 0.1 0.3 11.3 0.0 2.6 2 2 1 3 3 3 0 FlgA N-terminal domain TPR_8 PF13181.6 KFM78178.1 - 4e-24 82.8 12.8 0.001 19.1 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFM78178.1 - 2.3e-23 80.4 23.1 0.00041 20.2 0.1 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFM78178.1 - 8.7e-22 76.0 22.3 2.1e-05 24.1 0.2 8.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFM78178.1 - 6.7e-18 64.8 10.6 0.00035 20.8 0.2 6.6 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFM78178.1 - 5.4e-14 51.7 7.2 0.087 13.7 0.0 9.0 5 3 4 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM78178.1 - 9.3e-09 35.1 13.6 0.018 15.4 0.2 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM78178.1 - 1.2e-08 35.3 9.7 0.11 13.0 0.0 6.6 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM78178.1 - 1.5e-07 30.9 3.8 0.095 12.4 0.0 5.3 2 2 3 5 5 5 2 TPR repeat TPR_7 PF13176.6 KFM78178.1 - 1.8e-07 30.7 8.5 0.0081 16.1 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM78178.1 - 1.3e-05 25.5 15.8 2.2 9.1 0.0 8.7 9 2 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM78178.1 - 2.4e-05 24.9 6.4 0.61 10.8 0.1 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM78178.1 - 0.00043 20.1 5.5 0.062 13.2 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM78178.1 - 0.00086 18.8 0.8 0.62 9.4 0.2 2.8 3 0 0 3 3 3 2 MalT-like TPR region Fis1_TPR_C PF14853.6 KFM78178.1 - 0.004 17.2 0.2 0.038 14.1 0.0 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KFM78178.1 - 0.023 14.8 5.5 5.8 7.1 0.2 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM78178.1 - 0.12 12.7 22.6 0.41 10.9 0.0 5.4 4 2 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KFM78178.1 - 0.21 12.0 2.5 30 5.0 0.0 3.6 4 0 0 4 4 3 0 Bacterial transcriptional activator domain TFIID_20kDa PF03847.13 KFM78180.1 - 1.5e-06 28.6 0.9 1.5e-06 28.6 0.9 2.1 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KFM78180.1 - 0.024 14.9 0.0 0.2 12.0 0.1 2.5 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Kazal_2 PF07648.15 KFM78181.1 - 5.7e-09 36.0 0.8 5.7e-09 36.0 0.8 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM78181.1 - 5.1e-08 32.8 0.8 1.2e-07 31.6 0.8 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Lustrin_cystein PF14625.6 KFM78181.1 - 0.00064 20.0 7.0 0.00064 20.0 7.0 1.7 2 0 0 2 2 2 1 Lustrin, cysteine-rich repeated domain Laminin_G_2 PF02210.24 KFM78182.1 - 0.0035 17.9 0.0 0.0044 17.6 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM78182.1 - 0.14 12.4 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Laminin G domain CRAL_TRIO PF00650.20 KFM78185.1 - 3.7e-23 82.0 0.1 5.6e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM78185.1 - 0.031 14.4 0.1 0.076 13.2 0.0 1.6 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM78186.1 - 1.9e-25 89.4 0.0 3.1e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM78186.1 - 1.6e-06 28.2 1.0 3.2e-06 27.2 1.0 1.7 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM78186.1 - 0.00068 19.8 0.0 0.0027 17.9 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain EcoEI_R_C PF08463.10 KFM78186.1 - 0.032 14.4 0.4 0.11 12.7 0.3 2.0 2 0 0 2 2 2 0 EcoEI R protein C-terminal wnt PF00110.19 KFM78188.1 - 1.9e-19 70.4 0.1 2e-19 70.3 0.1 1.0 1 0 0 1 1 1 1 wnt family wnt PF00110.19 KFM78189.1 - 1.1e-49 169.8 14.8 1.2e-49 169.6 14.8 1.0 1 0 0 1 1 1 1 wnt family zf-RING_2 PF13639.6 KFM78190.1 - 1.8e-06 28.2 5.8 3.7e-06 27.2 5.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFM78190.1 - 2.3e-05 24.6 5.4 5e-05 23.5 5.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM78190.1 - 3e-05 23.8 6.1 6.3e-05 22.8 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFM78190.1 - 0.0014 18.6 1.5 0.0027 17.7 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFM78190.1 - 0.0015 18.2 1.3 0.0045 16.7 1.3 1.9 1 1 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 KFM78190.1 - 0.0023 18.1 6.4 0.056 13.6 6.4 2.5 1 1 0 1 1 1 1 FANCL C-terminal domain DZR PF12773.7 KFM78190.1 - 0.0049 16.9 3.4 0.014 15.4 3.4 1.7 1 1 0 1 1 1 1 Double zinc ribbon zf-C3HC4_2 PF13923.6 KFM78190.1 - 0.013 15.3 8.2 0.042 13.7 8.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM78190.1 - 0.015 15.3 8.0 0.037 14.0 8.0 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM78190.1 - 0.042 13.7 3.5 0.083 12.8 3.5 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 KFM78190.1 - 0.096 13.0 6.4 0.09 13.1 2.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 KFM78190.1 - 0.14 12.0 5.6 0.34 10.8 5.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM78190.1 - 0.14 12.2 9.9 0.11 12.6 5.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-ribbon_3 PF13248.6 KFM78190.1 - 0.22 11.0 3.1 1.9 8.0 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-UDP PF14569.6 KFM78190.1 - 1.3 9.2 5.0 2.5 8.3 5.0 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Phage_holin_3_6 PF07332.11 KFM78190.1 - 1.5 8.9 5.0 4 7.5 0.2 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III zf-C3HC4_4 PF15227.6 KFM78190.1 - 1.8 8.8 7.7 0.2 11.9 2.8 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KFM78190.1 - 2.5 7.8 8.8 6.3 6.5 7.8 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type BTK PF00779.19 KFM78191.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.5 2 0 0 2 2 2 0 BTK motif Ank_4 PF13637.6 KFM78194.1 - 1.7e-32 111.3 5.4 4.9e-14 52.5 0.1 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM78194.1 - 3.5e-31 107.6 4.7 2e-17 63.6 0.3 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM78194.1 - 4.2e-28 97.0 8.0 1.3e-11 44.5 0.3 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM78194.1 - 7.1e-25 84.4 2.7 3.1e-07 30.1 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KFM78194.1 - 2.2e-24 84.8 10.0 1.8e-05 25.0 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat PRKG1_interact PF15898.5 KFM78195.1 - 1.3e-12 48.5 1.1 1.4e-12 48.4 1.1 1.0 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain HALZ PF02183.18 KFM78195.1 - 0.00048 20.3 0.3 0.00054 20.1 0.3 1.1 1 0 0 1 1 1 1 Homeobox associated leucine zipper C2 PF00168.30 KFM78196.1 - 1.6e-57 192.1 0.9 1.2e-30 105.8 0.1 2.5 3 0 0 3 3 3 2 C2 domain CEP76-C2 PF15627.6 KFM78196.1 - 2.8e-05 23.7 0.0 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 CEP76 C2 domain PI3K_C2 PF00792.24 KFM78196.1 - 3.4e-05 23.8 0.0 0.046 13.6 0.0 2.4 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 TMEM154 PF15102.6 KFM78196.1 - 9.7e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family DOCK-C2 PF14429.6 KFM78196.1 - 0.0031 17.4 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Comm PF15957.5 KFM78196.1 - 0.0098 16.2 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Commissureless Herpes_gE PF02480.16 KFM78196.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PTEN_C2 PF10409.9 KFM78196.1 - 0.024 14.4 0.5 0.74 9.6 0.0 2.4 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein Shisa PF13908.6 KFM78196.1 - 0.049 13.9 6.9 0.11 12.8 6.5 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Transglut_C PF00927.22 KFM78196.1 - 0.049 13.8 0.7 9.6 6.4 0.1 2.5 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain CYYR1 PF10873.8 KFM78196.1 - 0.13 12.7 1.4 0.24 11.9 1.4 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 KFM78196.1 - 0.15 12.9 0.0 0.4 11.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM52 PF14979.6 KFM78196.1 - 8.2 6.3 15.3 3.3 7.6 9.7 2.5 1 1 1 2 2 2 0 Transmembrane 52 PGA2 PF07543.12 KFM78197.1 - 0.12 12.3 0.5 0.15 12.0 0.5 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 CRA PF06589.11 KFM78197.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Insulin PF00049.18 KFM78199.1 - 0.032 15.2 0.0 0.037 15.0 0.0 1.1 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family Insulin PF00049.18 KFM78200.1 - 9.8e-12 45.7 0.5 2.1e-11 44.7 0.5 1.6 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFM78200.1 - 0.072 13.1 3.0 7.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Insulin PF00049.18 KFM78201.1 - 6.5e-06 27.1 1.2 1.5e-05 25.9 0.3 1.8 2 0 0 2 2 2 1 Insulin/IGF/Relaxin family Insulin PF00049.18 KFM78202.1 - 2.4e-11 44.5 0.2 4.8e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFM78202.1 - 0.012 15.6 6.6 0.92 9.6 0.7 2.4 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type TFIID_30kDa PF03540.13 KFM78203.1 - 0.12 12.3 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit SNase PF00565.17 KFM78204.1 - 2.7e-67 224.0 0.2 1.1e-19 70.9 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KFM78204.1 - 1.6e-25 89.5 0.0 3.5e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 KFM78204.1 - 0.059 13.8 0.0 0.65 10.5 0.0 2.8 2 0 0 2 2 2 0 Agenet domain DUF2072 PF09845.9 KFM78206.1 - 0.017 15.3 0.5 0.02 15.2 0.5 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein zf-CCHC_2 PF13696.6 KFM78206.1 - 0.05 13.4 1.9 0.05 13.4 1.9 2.6 3 0 0 3 3 3 0 Zinc knuckle cobW PF02492.19 KFM78206.1 - 0.074 12.6 0.2 0.086 12.4 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Thioredoxin_7 PF13899.6 KFM78207.1 - 2.8e-17 62.7 0.1 8.4e-17 61.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 KFM78207.1 - 4.6e-16 58.4 0.0 9.9e-16 57.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KFM78207.1 - 1.6e-15 57.1 0.3 6.3e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 UBX domain TAP_C PF03943.13 KFM78207.1 - 0.0041 16.7 0.2 0.014 15.0 0.2 1.9 1 0 0 1 1 1 1 TAP C-terminal domain Peptidase_C1 PF00112.23 KFM78207.1 - 0.035 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Papain family cysteine protease CAP PF00188.26 KFM78207.1 - 0.057 14.2 0.1 0.12 13.3 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich secretory protein family UIM PF02809.20 KFM78207.1 - 0.07 13.1 2.3 0.17 11.9 2.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif UBA PF00627.31 KFM78207.1 - 0.088 12.7 1.1 0.29 11.1 0.0 2.3 3 0 0 3 3 3 0 UBA/TS-N domain G-patch PF01585.23 KFM78209.1 - 1.5e-10 40.8 1.7 2.9e-10 39.9 1.7 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFM78209.1 - 0.0007 19.6 0.4 0.0007 19.6 0.4 1.7 1 1 1 2 2 2 1 G-patch domain Aminotran_1_2 PF00155.21 KFM78212.1 - 1.5e-10 40.8 0.0 1.7e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Spectrin PF00435.21 KFM78213.1 - 2.7e-17 63.2 0.1 3.1e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 Spectrin repeat DEAD PF00270.29 KFM78214.1 - 1.7e-44 151.7 0.4 4.3e-44 150.4 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM78214.1 - 3.1e-31 108.0 1.2 6.3e-28 97.3 0.0 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 KFM78214.1 - 4.7e-07 29.0 2.6 0.0035 16.2 0.5 2.9 2 1 1 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 KFM78214.1 - 1.7e-06 28.1 1.7 4.7e-06 26.7 0.4 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFM78214.1 - 0.00038 20.7 0.1 0.0014 19.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain VPS28 PF03997.12 KFM78215.1 - 2.7e-40 138.1 0.9 3.1e-40 137.9 0.9 1.1 1 0 0 1 1 1 1 VPS28 protein zf_PR_Knuckle PF18445.1 KFM78215.1 - 0.095 12.5 0.7 0.27 11.1 0.1 2.1 1 1 1 2 2 2 0 PR zinc knuckle motif UNC-93 PF05978.16 KFM78215.1 - 0.16 11.7 0.0 1.7 8.3 0.0 1.9 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 RPEL PF02755.15 KFM78216.1 - 2e-31 106.7 17.6 2.6e-07 30.1 4.7 4.7 4 0 0 4 4 4 4 RPEL repeat Orai-1 PF07856.12 KFM78218.1 - 2.1e-50 170.8 9.5 2.5e-50 170.6 9.5 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF4492 PF14899.6 KFM78218.1 - 0.0011 18.9 0.1 0.0023 17.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4492) TRP PF06011.12 KFM78218.1 - 0.033 12.9 6.2 0.039 12.7 6.2 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel WSS_VP PF12175.8 KFM78218.1 - 0.1 12.0 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP EI24 PF07264.11 KFM78218.1 - 0.2 11.9 9.2 0.81 9.9 1.5 2.4 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Phage_holin_3_6 PF07332.11 KFM78218.1 - 0.52 10.4 12.1 0.16 12.0 3.3 2.1 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4199 PF13858.6 KFM78218.1 - 0.87 10.0 6.3 0.15 12.5 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF3169 PF11368.8 KFM78218.1 - 2 7.9 11.1 18 4.8 11.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) MAM33 PF02330.16 KFM78219.1 - 3.8e-32 112.0 2.6 5.2e-32 111.5 2.6 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein bZIP_2 PF07716.15 KFM78220.1 - 9.2e-15 54.5 10.6 9.2e-15 54.5 10.6 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM78220.1 - 4e-05 23.6 5.7 8.7e-05 22.5 5.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor SR-25 PF10500.9 KFM78220.1 - 4.7 6.8 16.0 6.8 6.2 16.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RT_RNaseH_2 PF17919.1 KFM78222.1 - 1.1e-35 121.6 0.2 2.3e-35 120.6 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM78222.1 - 2.4e-29 101.7 0.0 4.9e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 KFM78222.1 - 0.0066 17.1 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_3 PF13456.6 KFM78222.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase-like gag-asp_proteas PF13975.6 KFM78222.1 - 0.17 12.5 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_2 PF07727.14 KFM78223.1 - 7.4e-18 65.1 0.0 9.9e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1609 PF07753.11 KFM78223.1 - 0.034 13.7 0.5 0.046 13.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) Galactosyl_T PF01762.21 KFM78224.1 - 4.5e-38 131.0 0.0 1.3e-37 129.6 0.0 1.7 2 0 0 2 2 2 1 Galactosyltransferase WAC_Acf1_DNA_bd PF10537.9 KFM78225.1 - 3.9e-33 114.0 0.1 3.9e-33 114.0 0.1 2.8 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal Bromodomain PF00439.25 KFM78225.1 - 1.9e-19 69.5 0.1 4.9e-19 68.2 0.1 1.7 1 0 0 1 1 1 1 Bromodomain WSD PF15613.6 KFM78225.1 - 6.6e-19 68.2 0.1 6.6e-19 68.2 0.1 4.7 5 1 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 KFM78225.1 - 4.9e-17 61.5 33.3 7e-11 41.8 7.3 3.8 3 0 0 3 3 3 2 PHD-finger DDT PF02791.17 KFM78225.1 - 2e-11 44.0 0.4 5.2e-11 42.7 0.4 1.8 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KFM78225.1 - 5.9e-06 25.7 2.1 5.9e-06 25.7 2.1 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_2 PF13831.6 KFM78225.1 - 0.00042 19.8 5.3 0.00042 19.8 5.3 3.4 3 0 0 3 3 3 1 PHD-finger PXA PF02194.15 KFM78225.1 - 0.51 10.3 2.3 0.8 9.7 0.0 2.5 2 0 0 2 2 2 0 PXA domain C1_2 PF03107.16 KFM78225.1 - 1.5 9.2 17.6 2.2 8.7 1.0 3.5 3 0 0 3 3 3 0 C1 domain C1_1 PF00130.22 KFM78225.1 - 6.8 6.7 15.1 0.48 10.3 3.4 2.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ANF_receptor PF01094.28 KFM78226.1 - 6.9e-08 32.0 0.0 8.1e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region DDE_Tnp_IS1595 PF12762.7 KFM78227.1 - 2e-06 27.9 0.1 2e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Sushi PF00084.20 KFM78230.1 - 3.8e-58 193.9 66.5 1.3e-09 38.5 4.7 7.2 7 0 0 7 7 7 7 Sushi repeat (SCR repeat) HRM PF02793.22 KFM78230.1 - 0.99 9.7 55.7 2.7 8.4 0.7 8.6 4 2 3 7 7 7 0 Hormone receptor domain DUF1736 PF08409.11 KFM78232.1 - 1.4e-32 111.5 1.6 3.5e-32 110.2 1.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_1 PF00515.28 KFM78232.1 - 7.4e-17 60.4 5.8 1.8e-08 33.9 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM78232.1 - 1.4e-16 59.9 1.1 6.8e-09 35.3 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 KFM78232.1 - 9.6e-12 44.1 4.3 0.00036 20.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM78232.1 - 2.2e-11 43.3 1.0 0.001 19.3 0.4 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM78232.1 - 3.9e-11 42.2 6.0 4.3e-06 26.4 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM78232.1 - 6.3e-10 38.4 2.1 0.00062 19.6 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM78232.1 - 5.2e-09 35.7 4.4 0.0066 16.3 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM78232.1 - 1.5e-08 34.8 4.9 8.3e-05 22.8 1.2 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM78232.1 - 2.8e-08 34.3 6.0 1.7e-05 25.4 0.6 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFM78232.1 - 9.4e-06 25.8 0.0 0.035 14.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM78232.1 - 0.00012 22.5 1.4 0.00038 20.9 0.9 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM78232.1 - 0.00081 20.0 1.2 0.07 14.0 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM78232.1 - 0.0021 18.2 0.3 0.0038 17.3 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat FAT PF02259.23 KFM78232.1 - 0.045 13.0 1.2 0.099 11.8 0.0 1.8 2 0 0 2 2 2 0 FAT domain TPR_6 PF13174.6 KFM78232.1 - 0.054 14.2 2.7 0.056 14.1 0.3 2.4 2 1 1 3 3 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFM78232.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 SHNi-TPR Wzy_C_2 PF11846.8 KFM78232.1 - 0.14 12.0 1.6 5.6 6.8 1.6 3.0 1 1 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal TPR_3 PF07720.12 KFM78232.1 - 0.16 12.0 3.2 0.12 12.4 0.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KFM78232.1 - 0.23 11.6 0.9 1 9.5 0.1 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Med19 PF10278.9 KFM78233.1 - 1.7e-71 239.8 20.2 2.1e-71 239.5 20.2 1.0 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 Neur_chan_memb PF02932.16 KFM78233.1 - 0.086 12.9 2.2 0.089 12.8 2.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCDC106 PF15794.5 KFM78233.1 - 0.45 10.2 17.2 0.67 9.6 17.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RNA_pol_Rpc4 PF05132.14 KFM78233.1 - 0.97 9.9 13.1 1.6 9.2 13.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tim54 PF11711.8 KFM78233.1 - 1.5 7.5 15.0 2.1 7.1 15.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Band_3_cyto PF07565.13 KFM78233.1 - 4.5 7.0 10.8 6.2 6.5 10.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain LEA_3 PF03242.13 KFM78233.1 - 5.3 7.8 5.2 2.3 9.0 2.4 1.7 1 1 1 2 2 2 0 Late embryogenesis abundant protein CPSF100_C PF13299.6 KFM78233.1 - 5.5 7.2 9.1 9.7 6.3 9.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 KFM78233.1 - 8.3 5.3 5.2 11 4.9 5.2 1.1 1 0 0 1 1 1 0 CLN3 protein SLC12 PF03522.15 KFM78233.1 - 9.6 5.1 12.0 13 4.7 12.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Ank_2 PF12796.7 KFM78237.1 - 8.8e-22 77.5 0.3 3.3e-12 46.8 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM78237.1 - 3.1e-17 62.7 1.9 1.3e-07 32.1 0.0 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM78237.1 - 3.1e-15 54.7 2.3 0.00019 21.6 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFM78237.1 - 5.7e-14 51.8 6.6 0.00023 21.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFM78237.1 - 2.8e-11 43.4 1.1 0.0006 20.1 0.0 4.5 4 2 1 5 5 5 3 Ankyrin repeats (many copies) DUF4552 PF15089.6 KFM78238.1 - 0.045 12.8 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) zf-LITAF-like PF10601.9 KFM78239.1 - 2.5e-22 78.9 12.7 3.1e-22 78.6 12.7 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain PIG-F PF06699.11 KFM78239.1 - 0.1 12.7 2.7 0.15 12.3 2.7 1.1 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F PDCD2_C PF04194.13 KFM78239.1 - 5.7 7.0 5.1 8.2 6.5 5.1 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Arf PF00025.21 KFM78241.1 - 1e-54 184.6 0.0 1.2e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFM78241.1 - 4.7e-13 49.0 0.8 7.5e-08 31.9 0.2 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFM78241.1 - 7e-13 48.5 0.0 7.8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM78241.1 - 4.3e-12 46.3 0.0 6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFM78241.1 - 4e-11 42.7 0.0 5.4e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFM78241.1 - 8.3e-07 29.1 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM78241.1 - 1.8e-06 27.5 0.1 2.3e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM78241.1 - 0.00085 18.9 0.1 0.059 12.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KFM78241.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 KFM78241.1 - 0.0055 17.0 0.0 0.0088 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 KFM78241.1 - 0.03 13.9 0.3 0.081 12.5 0.3 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 KFM78241.1 - 0.053 12.8 0.0 0.6 9.3 0.0 2.0 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 KFM78241.1 - 0.073 13.0 0.1 4.5 7.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Thioredoxin_9 PF14595.6 KFM78241.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin AAA_29 PF13555.6 KFM78241.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribophorin_I PF04597.14 KFM78242.1 - 5.8e-146 487.2 7.6 8.5e-146 486.6 7.6 1.2 1 0 0 1 1 1 1 Ribophorin I DNA_repr_REX1B PF14966.6 KFM78242.1 - 3.5e-05 24.4 1.1 8.4e-05 23.2 1.1 1.7 1 0 0 1 1 1 1 DNA repair REX1-B CD24 PF14984.6 KFM78242.1 - 0.16 12.2 0.3 0.39 11.0 0.3 1.6 1 0 0 1 1 1 0 CD24 protein Seadorna_Vp10 PF07322.11 KFM78242.1 - 0.24 10.8 1.6 0.32 10.4 0.1 1.9 2 0 0 2 2 2 0 Seadornavirus Vp10 zf-C2H2_4 PF13894.6 KFM78243.1 - 0.0027 18.4 4.3 0.029 15.2 4.3 3.1 1 0 0 1 1 1 1 C2H2-type zinc finger NACHT_N PF17100.5 KFM78243.1 - 4 7.2 8.2 15 5.4 0.9 3.1 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase zf-C2H2 PF00096.26 KFM78243.1 - 9.2 6.9 9.1 1.6 9.4 3.7 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type SMC_N PF02463.19 KFM78246.1 - 1.4e-39 135.8 0.1 1.7e-39 135.5 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFM78246.1 - 1.4e-11 45.3 0.1 1.7e-11 45.0 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KFM78246.1 - 9e-09 35.5 0.4 1.1e-08 35.2 0.4 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFM78246.1 - 1.9e-07 31.2 0.1 2.6e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM78246.1 - 4.1e-05 23.2 0.0 6.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KFM78246.1 - 0.018 15.6 0.1 0.025 15.1 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_27 PF13514.6 KFM78246.1 - 0.093 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM78246.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KFM78246.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NUDIX PF00293.28 KFM78247.1 - 6.5e-17 61.8 0.0 9.6e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 KFM78247.1 - 0.038 13.6 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase Pkinase_Tyr PF07714.17 KFM78248.1 - 1.8e-48 165.1 0.0 2.7e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM78248.1 - 1.1e-39 136.4 0.0 3.3e-39 134.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFM78248.1 - 8.1e-06 25.3 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFM78248.1 - 0.00019 20.4 0.0 0.0004 19.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM78248.1 - 0.079 12.9 0.0 2.2 8.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1177 PF06675.11 KFM78248.1 - 0.18 10.6 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) DUF4934 PF16288.5 KFM78249.1 - 0.036 14.0 1.3 0.067 13.1 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4934) PDZ_assoc PF10600.9 KFM78253.1 - 1.1 10.1 3.5 1.4 9.8 0.0 3.2 3 0 0 3 3 3 0 PDZ-associated domain of NMDA receptors I-set PF07679.16 KFM78256.1 - 1.3e-45 153.4 0.0 5.5e-16 58.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM78256.1 - 4.6e-45 152.1 2.1 3e-16 59.8 0.4 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM78256.1 - 9.1e-33 112.3 0.2 1.1e-09 38.3 0.2 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM78256.1 - 3.1e-30 104.3 0.2 1.9e-11 44.1 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM78256.1 - 4.5e-11 42.9 4.5 0.27 11.4 0.0 5.9 3 3 3 6 6 6 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM78256.1 - 7e-11 41.5 0.0 0.0012 18.3 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 KFM78256.1 - 7.7e-09 35.7 0.0 0.036 14.3 0.0 3.2 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFM78256.1 - 8.3e-07 29.0 1.5 0.4 10.8 0.2 3.4 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM78256.1 - 1.2e-06 28.9 0.0 0.23 11.9 0.0 3.2 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 KFM78256.1 - 6.3e-05 22.7 0.3 2.2 8.1 0.0 3.8 3 1 0 3 3 3 2 Adenovirus E3 region protein CR1 Izumo-Ig PF16706.5 KFM78256.1 - 0.0007 19.6 0.1 6.7 6.8 0.0 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM78256.1 - 0.0035 17.4 0.1 30 4.8 0.0 3.7 3 1 0 3 3 3 0 C17orf99 Ig domain C2-set PF05790.15 KFM78256.1 - 0.01 16.0 0.1 2.2 8.5 0.0 3.5 5 0 0 5 5 4 0 Immunoglobulin C2-set domain Herpes_gE PF02480.16 KFM78256.1 - 0.01 14.6 0.1 2.1 7.0 0.0 2.9 1 1 2 3 3 3 0 Alphaherpesvirus glycoprotein E Herpes_UL82_83 PF05784.11 KFM78256.1 - 0.043 12.6 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Betaherpesvirus UL82/83 protein N terminus MBG_2 PF18676.1 KFM78256.1 - 0.14 12.8 0.3 0.51 11.0 0.0 2.0 2 0 0 2 2 2 0 MBG domain (YGX type) Laminin_G_2 PF02210.24 KFM78257.1 - 1e-71 239.4 0.0 1.2e-26 93.8 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 KFM78257.1 - 1e-69 232.8 0.0 4.1e-25 88.5 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Ig_3 PF13927.6 KFM78257.1 - 5.4e-60 200.0 0.3 1.6e-11 44.6 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFM78257.1 - 6.1e-50 167.2 0.0 1.2e-12 47.7 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM78257.1 - 1.3e-45 153.6 0.0 4.5e-11 42.9 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFM78257.1 - 1.4e-42 143.8 0.0 8.6e-09 35.5 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFM78257.1 - 5.8e-20 71.5 1.3 0.41 10.9 0.0 9.8 5 5 5 10 10 10 4 Immunoglobulin V-set domain EGF PF00008.27 KFM78257.1 - 1.5e-18 66.8 57.4 5e-07 29.9 5.5 4.9 4 0 0 4 4 4 4 EGF-like domain Ig_6 PF18452.1 KFM78257.1 - 3.9e-14 51.9 0.0 0.00057 19.4 0.0 5.7 6 0 0 6 6 6 3 Immunoglobulin domain Izumo-Ig PF16706.5 KFM78257.1 - 4.3e-09 36.3 0.0 2.1 8.4 0.0 5.5 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFM78257.1 - 9.9e-09 35.5 0.0 0.0037 17.6 0.0 5.0 5 0 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Laminin_G_3 PF13385.6 KFM78257.1 - 6.8e-08 32.8 0.0 0.27 11.4 0.0 3.4 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily C2-set_2 PF08205.12 KFM78257.1 - 8e-07 29.0 0.6 0.31 11.2 0.0 5.0 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain hEGF PF12661.7 KFM78257.1 - 1e-06 29.1 47.4 0.0048 17.5 4.4 5.4 4 1 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.13 KFM78257.1 - 0.008 16.5 66.3 0.033 14.5 9.2 4.6 4 0 0 4 4 4 2 EGF-like domain VIT1 PF01988.19 KFM78258.1 - 2.8 7.8 0.0 2.8 7.8 0.0 4.4 5 1 0 5 5 5 0 VIT family zf-H2C2_2 PF13465.6 KFM78260.1 - 8.3e-66 215.7 70.5 1.1e-08 35.1 1.1 11.2 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78260.1 - 1.2e-37 126.3 97.5 9.8e-06 25.8 0.7 10.1 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78260.1 - 3.5e-26 89.6 87.2 0.00067 20.3 1.4 10.1 10 0 0 10 10 10 8 C2H2-type zinc finger zf-met PF12874.7 KFM78260.1 - 2.8e-20 72.0 81.6 0.0019 18.5 1.9 10.1 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM78260.1 - 9.3e-11 41.5 77.2 0.0054 16.7 1.1 9.8 10 0 0 10 10 10 7 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM78260.1 - 1.9e-10 40.6 23.5 0.57 10.3 0.1 8.2 5 2 3 8 8 8 3 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.6 KFM78260.1 - 2.5e-08 33.5 54.1 0.0088 15.8 0.6 10.3 10 0 0 10 10 9 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM78260.1 - 1.4e-07 31.7 60.2 0.023 15.0 0.4 10.1 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-RRPl_C4 PF17026.5 KFM78260.1 - 7.1e-05 22.9 39.7 0.021 14.9 5.6 4.1 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM78260.1 - 0.0027 17.8 38.9 6.2 7.0 0.3 8.6 9 0 0 9 9 8 1 DBF zinc finger Tox-HNH-HHH PF15637.6 KFM78260.1 - 0.012 15.8 7.6 6.4 7.0 0.0 4.5 1 1 2 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif GAGA PF09237.11 KFM78260.1 - 0.026 14.3 25.4 0.48 10.3 1.2 7.3 1 1 8 9 9 9 0 GAGA factor zinc_ribbon_15 PF17032.5 KFM78260.1 - 0.16 12.7 35.0 0.38 11.5 1.5 4.5 2 1 3 5 5 4 0 zinc-ribbon family BolA PF01722.18 KFM78260.1 - 0.27 11.5 21.5 2 8.7 1.9 5.7 1 1 7 8 8 8 0 BolA-like protein OSTMP1 PF09777.9 KFM78260.1 - 0.33 10.3 26.7 0.34 10.3 15.8 2.7 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor ADK_lid PF05191.14 KFM78260.1 - 0.8 9.7 31.1 0.74 9.9 2.4 5.9 4 3 2 6 6 6 0 Adenylate kinase, active site lid TRAF6_Z2 PF18048.1 KFM78260.1 - 0.85 9.8 52.3 0.35 11.0 0.6 9.1 10 0 0 10 10 9 0 TNF receptor-associated factor 6 zinc finger 2 FYVE PF01363.21 KFM78260.1 - 0.87 9.8 50.7 6.8 6.9 16.0 4.7 2 2 2 4 4 4 0 FYVE zinc finger zf-MYST PF17772.1 KFM78260.1 - 0.95 9.1 49.0 0.24 11.0 0.5 8.4 3 3 6 9 9 9 0 MYST family zinc finger domain Zf_RING PF16744.5 KFM78260.1 - 2.2 8.5 49.4 6.4 7.0 3.1 8.4 1 1 7 8 8 8 0 KIAA1045 RING finger zf-C2H2_9 PF16293.5 KFM78260.1 - 2.7 7.9 50.4 4 7.4 0.6 9.1 3 2 7 10 10 9 0 C2H2 type zinc-finger (1 copy) C5HCH PF17982.1 KFM78260.1 - 6.4 7.0 39.9 0.22 11.7 1.9 7.6 6 2 1 7 7 7 0 NSD Cys-His rich domain Viral_cys_rich PF08008.12 KFM78260.1 - 8.1 6.6 10.7 26 4.9 0.5 3.9 2 2 2 4 4 4 0 Viral cysteine rich LRR_8 PF13855.6 KFM78261.1 - 8.7e-49 163.1 31.4 4.4e-17 61.6 2.7 7.0 2 2 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFM78261.1 - 2.1e-23 82.0 30.2 9.7e-07 29.0 0.4 6.8 3 3 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM78261.1 - 2e-15 56.9 0.1 4.1e-08 33.3 0.0 3.2 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 KFM78261.1 - 4.4e-12 46.4 0.1 3.5e-11 43.5 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM78261.1 - 6.8e-12 45.3 0.0 1.8e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_9 PF14580.6 KFM78261.1 - 1.1e-08 34.7 10.8 0.0014 18.2 0.0 4.3 1 1 5 6 6 6 5 Leucine-rich repeat ig PF00047.25 KFM78261.1 - 9.5e-08 32.1 0.1 5.7e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 KFM78261.1 - 1e-07 31.5 25.3 5.7 7.9 0.1 9.9 10 0 0 10 10 9 1 Leucine Rich Repeat fn3 PF00041.21 KFM78261.1 - 6.5e-07 29.6 0.1 2e-06 28.0 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Ig_2 PF13895.6 KFM78261.1 - 1.7e-05 25.1 0.0 5.7e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.6 KFM78261.1 - 0.0039 17.1 28.9 5.6 7.3 0.0 8.9 9 0 0 9 9 9 2 Leucine Rich repeat V-set PF07686.17 KFM78261.1 - 0.012 15.8 0.2 0.065 13.4 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin V-set domain Syndecan PF01034.20 KFM78261.1 - 0.024 14.6 0.3 1.2 9.1 0.4 2.3 2 0 0 2 2 2 0 Syndecan domain Pur_ac_phosph_N PF16656.5 KFM78261.1 - 0.028 15.0 0.1 0.074 13.6 0.1 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain LRRNT PF01462.18 KFM78261.1 - 0.052 13.2 4.3 0.17 11.6 4.3 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain AhpC-TSA PF00578.21 KFM78263.1 - 6.7e-35 119.7 0.0 9.9e-35 119.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM78263.1 - 8.6e-14 51.5 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFM78263.1 - 5.4e-13 48.6 0.0 9.8e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DoxX_2 PF13564.6 KFM78264.1 - 2.2e-13 50.2 0.8 4.3e-13 49.3 0.8 1.5 1 1 0 1 1 1 1 DoxX-like family ArAE_2_N PF10337.9 KFM78264.1 - 0.52 9.3 3.7 5.5 5.9 1.4 2.3 1 1 1 2 2 2 0 Putative ER transporter, 6TM, N-terminal Rho_N PF07498.12 KFM78268.1 - 0.09 12.7 0.2 0.22 11.5 0.1 1.7 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain DUF1075 PF06388.11 KFM78270.1 - 3.3e-20 72.3 0.2 3.6e-20 72.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) DUF4534 PF15049.6 KFM78270.1 - 0.0087 15.8 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4534) UCH PF00443.29 KFM78271.1 - 3.9e-44 151.1 0.0 8.5e-44 150.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFM78271.1 - 1.7e-22 79.8 0.0 8.8e-22 77.5 0.0 2.4 1 1 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KFM78271.1 - 2.7e-05 23.9 0.0 0.00084 19.0 0.0 2.2 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 KFM78271.1 - 0.002 18.1 0.7 0.0043 17.0 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain DDE_Tnp_1_7 PF13843.6 KFM78273.1 - 1.6e-96 323.7 0.1 2.4e-96 323.1 0.1 1.3 1 0 0 1 1 1 1 Transposase IS4 Pkinase_Tyr PF07714.17 KFM78274.1 - 2.7e-18 66.2 0.0 4.2e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KFM78275.1 - 9.3e-53 179.1 0.0 1.1e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM78275.1 - 3.4e-21 75.8 0.4 8.2e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KFM78275.1 - 0.036 12.9 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFM78275.1 - 0.055 13.4 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFM78275.1 - 0.11 12.0 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KFM78275.1 - 0.11 11.4 0.2 0.22 10.4 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Ig_3 PF13927.6 KFM78276.1 - 1.6e-23 83.1 1.0 6e-14 52.4 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM78276.1 - 5.4e-22 77.7 0.1 3.6e-14 52.6 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 KFM78276.1 - 2.8e-21 75.5 0.2 5.3e-10 39.3 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFM78276.1 - 3.5e-18 65.7 0.2 1.1e-09 38.5 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM78276.1 - 2.5e-10 40.5 0.9 0.0039 17.3 0.1 4.6 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM78276.1 - 7.5e-06 26.1 0.9 0.036 14.3 0.0 3.5 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFM78276.1 - 9.2e-06 25.1 0.0 0.2 11.3 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM78276.1 - 0.0043 17.1 0.1 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 KFM78276.1 - 0.0093 16.2 0.3 9.4 6.5 0.0 2.9 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 C1-set PF07654.15 KFM78276.1 - 0.016 15.6 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C1-set domain I-set PF07679.16 KFM78277.1 - 2.2e-05 24.5 0.1 2.2e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM78277.1 - 9.7e-05 22.5 0.1 0.00011 22.3 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM78277.1 - 0.00028 21.0 0.1 0.00028 21.0 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM78277.1 - 0.00065 20.2 0.0 0.00075 20.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFM78277.1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 1.1 1 0 0 1 1 1 1 Adenovirus E3 region protein CR1 Ig_2 PF13895.6 KFM78277.1 - 0.0067 16.7 0.1 0.0068 16.7 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.16 KFM78277.1 - 0.011 14.5 0.0 0.011 14.5 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ig_4 PF16680.5 KFM78277.1 - 0.012 15.8 0.2 0.014 15.7 0.2 1.1 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM78278.1 - 0.12 12.8 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain THF_DHG_CYH_C PF02882.19 KFM78279.1 - 1.6e-69 232.3 2.3 2.2e-69 231.8 2.3 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFM78279.1 - 1e-36 125.7 0.8 1.7e-36 125.0 0.8 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KFM78279.1 - 0.00053 19.0 0.2 0.00085 18.3 0.2 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family AlaDh_PNT_C PF01262.21 KFM78279.1 - 0.014 14.7 0.4 0.027 13.8 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Adeno_PV PF03910.13 KFM78279.1 - 0.068 11.9 0.1 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV NAD_binding_2 PF03446.15 KFM78279.1 - 0.099 12.8 0.1 2.3 8.4 0.1 2.3 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TPR_5 PF12688.7 KFM78281.1 - 0.0057 16.9 0.0 0.0061 16.8 0.0 1.0 1 0 0 1 1 1 1 Tetratrico peptide repeat Nup153 PF08604.10 KFM78282.1 - 5.4e-28 98.1 20.0 5.4e-28 98.1 20.0 3.5 2 1 0 3 3 3 1 Nucleoporin Nup153-like zf-RanBP PF00641.18 KFM78282.1 - 0.01 15.1 7.8 0.01 15.1 7.8 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.7 KFM78282.1 - 0.57 10.3 3.4 1.5 8.9 3.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon ErmC PF06308.11 KFM78282.1 - 8.9 6.8 8.0 7.6 7.0 0.4 3.1 2 1 1 3 3 3 0 23S rRNA methylastransferase leader peptide (ErmCL) GFO_IDH_MocA PF01408.22 KFM78285.1 - 3.7e-21 76.2 0.0 4.6e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KFM78285.1 - 0.0011 19.5 0.0 0.0017 19.0 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ApbA PF02558.16 KFM78285.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Semialdhyde_dh PF01118.24 KFM78285.1 - 0.01 16.2 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Putative_PNPOx PF01243.20 KFM78285.1 - 0.027 14.7 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Gp_dh_N PF00044.24 KFM78285.1 - 0.031 14.6 0.3 3.1 8.2 0.2 2.4 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFM78285.1 - 0.045 14.0 0.0 0.073 13.3 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain OpuAC PF04069.12 KFM78285.1 - 0.059 12.9 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Methyltransf_25 PF13649.6 KFM78285.1 - 0.18 12.5 0.0 0.28 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Frizzled PF01534.17 KFM78286.1 - 0.008 15.2 1.5 0.01 14.9 1.5 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF1640 PF07798.11 KFM78286.1 - 0.015 15.3 1.1 0.02 14.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Apolipoprotein PF01442.18 KFM78286.1 - 0.018 14.9 0.9 0.024 14.5 0.9 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain FlaC_arch PF05377.11 KFM78286.1 - 0.76 10.2 5.7 0.7 10.3 0.8 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) MMR_HSR1 PF01926.23 KFM78288.1 - 3.9e-15 55.9 0.9 1.3e-13 51.1 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM78288.1 - 3.1e-07 30.1 0.1 0.00028 20.4 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM78288.1 - 3e-06 27.2 0.1 0.06 13.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KFM78288.1 - 0.031 13.6 0.0 0.069 12.5 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 KFM78288.1 - 1.2 9.1 6.5 4.6 7.3 0.2 3.8 3 2 1 4 4 4 0 Dynamin family UreD PF01774.17 KFM78289.1 - 0.0003 20.8 0.0 0.00037 20.5 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein zf-H2C2_2 PF13465.6 KFM78290.1 - 8e-70 228.4 95.7 1.8e-07 31.3 1.6 14.6 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78290.1 - 1.9e-49 163.5 125.0 7.9e-05 22.9 1.3 14.5 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78290.1 - 1.5e-37 125.0 113.8 0.0031 18.2 4.2 14.5 14 0 0 14 14 14 14 C2H2-type zinc finger zf-met PF12874.7 KFM78290.1 - 1.9e-20 72.5 96.6 0.00054 20.2 0.8 14.1 14 0 0 14 14 14 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM78290.1 - 6.4e-20 70.9 80.8 0.00021 21.5 0.7 14.3 14 0 0 14 14 14 8 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFM78290.1 - 1.8e-07 31.3 70.8 0.046 14.0 1.4 9.0 3 1 4 9 9 9 8 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFM78290.1 - 1.4e-05 24.9 88.6 0.017 15.1 0.2 13.7 14 0 0 14 14 14 6 C2H2-type zinc finger DUF3268 PF11672.8 KFM78290.1 - 0.00028 21.2 39.4 0.069 13.5 0.5 6.6 6 2 1 7 7 7 3 zinc-finger-containing domain BolA PF01722.18 KFM78290.1 - 0.00081 19.6 13.7 23 5.3 0.1 7.5 4 3 1 6 6 5 0 BolA-like protein zf-MYST PF17772.1 KFM78290.1 - 0.013 15.1 52.6 4.3 7.0 0.1 11.2 5 3 5 10 10 10 0 MYST family zinc finger domain zf-C2H2_3rep PF18868.1 KFM78290.1 - 0.029 15.1 57.9 0.17 12.6 3.7 9.3 2 2 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-Sec23_Sec24 PF04810.15 KFM78290.1 - 0.35 11.0 56.2 8.9 6.5 0.5 13.0 11 3 2 13 13 13 0 Sec23/Sec24 zinc finger zinc_ribbon_15 PF17032.5 KFM78290.1 - 0.55 11.0 52.3 1.1 10.1 0.4 7.3 1 1 7 8 8 8 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM78290.1 - 8.5 6.6 54.1 14 5.9 4.5 9.6 6 4 3 9 9 9 0 Zinc ribbon domain Chorein_N PF12624.7 KFM78291.1 - 7.8e-21 74.4 0.2 8.8e-21 74.2 0.2 1.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 KFM78293.1 - 1.1e-42 146.5 2.6 2.3e-42 145.4 2.6 1.6 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 KFM78293.1 - 5.5e-11 42.3 0.4 3.4e-08 33.2 0.1 2.4 2 0 0 2 2 2 2 Repeating coiled region of VPS13 VPS13_mid_rpt PF16910.5 KFM78294.1 - 3.3e-23 82.3 2.1 1.9e-22 79.8 2.1 1.9 1 1 0 1 1 1 1 Repeating coiled region of VPS13 PRMT5_C PF17286.2 KFM78294.1 - 0.064 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Cloacin_immun PF03513.14 KFM78294.1 - 0.19 12.1 1.1 0.32 11.4 0.1 1.9 2 0 0 2 2 2 0 Cloacin immunity protein SHR-BD PF06650.12 KFM78297.1 - 8e-79 264.8 0.1 1.3e-76 257.5 0.0 3.3 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 KFM78297.1 - 1.7e-27 96.4 7.0 1.3e-22 80.4 0.2 3.8 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal UBA PF00627.31 KFM78297.1 - 1e-05 25.3 0.1 1.9e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain VPS13_mid_rpt PF16910.5 KFM78297.1 - 2.2e-05 24.0 3.9 2.2e-05 24.0 3.9 5.9 5 2 0 5 5 5 2 Repeating coiled region of VPS13 Mito_carr PF00153.27 KFM78297.1 - 0.042 13.8 0.2 0.56 10.2 0.1 2.8 3 0 0 3 3 3 0 Mitochondrial carrier protein DUF1110 PF06533.12 KFM78297.1 - 0.094 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) Sas10 PF09368.10 KFM78299.1 - 1.7e-20 73.3 10.7 1.7e-20 73.3 10.7 2.0 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KFM78299.1 - 8.4e-08 32.7 1.5 8.4e-08 32.7 1.5 3.0 3 2 0 3 3 3 1 Sas10/Utp3/C1D family Asp_Arg_Hydrox PF05118.15 KFM78299.1 - 0.0061 16.4 0.6 0.048 13.5 0.0 2.4 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase DUF325 PF03804.13 KFM78299.1 - 0.03 14.4 0.2 0.069 13.2 0.2 1.5 1 0 0 1 1 1 0 Viral proteins of unknown function VPS9 PF02204.18 KFM78299.1 - 0.2 11.9 2.2 0.26 11.5 0.2 2.3 2 1 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain SIT PF15330.6 KFM78299.1 - 7.8 7.0 14.2 0.72 10.3 0.7 3.2 2 1 1 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT DUF543 PF04418.12 KFM78300.1 - 1.4e-19 69.9 0.3 1.6e-19 69.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Formyl_trans_N PF00551.19 KFM78301.1 - 1.4e-55 187.9 0.4 1.5e-55 187.7 0.4 1.0 1 0 0 1 1 1 1 Formyl transferase ATP-synt_A PF00119.20 KFM78302.1 - 3.2e-06 27.2 4.7 4.1e-06 26.9 4.7 1.2 1 0 0 1 1 1 1 ATP synthase A chain DUF5535 PF17687.1 KFM78304.1 - 0.0077 16.4 1.8 0.025 14.7 1.9 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5535) Ldl_recept_b PF00058.17 KFM78305.1 - 2e-62 207.4 15.3 4.5e-10 39.8 0.0 9.5 9 0 0 9 9 9 8 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 KFM78305.1 - 2.2e-19 69.4 25.0 8.2e-10 38.7 6.9 2.7 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 KFM78305.1 - 4.5e-16 58.8 24.7 4.8e-11 42.8 8.0 3.4 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site SGL PF08450.12 KFM78305.1 - 0.0015 18.2 4.8 3.7 7.1 0.0 4.7 2 2 2 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region Ldl_recept_b PF00058.17 KFM78306.1 - 1.5e-43 147.0 1.5 6.1e-15 55.4 0.0 4.3 4 0 0 4 4 4 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFM78306.1 - 1.2e-11 44.6 10.5 1.8e-11 44.1 10.5 1.3 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site SGL PF08450.12 KFM78306.1 - 1.3e-06 28.2 0.1 0.012 15.3 0.0 3.2 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 KFM78306.1 - 0.0014 18.5 0.1 0.0031 17.4 0.1 1.6 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF PF00008.27 KFM78306.1 - 0.0041 17.4 7.6 0.0079 16.5 7.6 1.4 1 0 0 1 1 1 1 EGF-like domain SL4P PF17618.2 KFM78306.1 - 0.0087 16.1 2.4 3.1 7.9 0.1 3.9 3 1 1 4 4 4 1 Uncharacterized Strongylid L4 protein EGF_3 PF12947.7 KFM78306.1 - 0.18 12.0 5.8 0.35 11.1 5.8 1.5 1 0 0 1 1 1 0 EGF domain DUF4551 PF15087.6 KFM78306.1 - 0.23 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Plasmod_Pvs28 PF06247.11 KFM78306.1 - 0.76 10.1 5.9 1.3 9.4 5.9 1.4 1 0 0 1 1 1 0 Pvs28 EGF domain MADF_DNA_bdg PF10545.9 KFM78307.1 - 8.8e-19 67.6 1.3 8.8e-19 67.6 1.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 KFM78307.1 - 0.01 16.2 4.8 0.01 16.2 4.8 2.1 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain PMD PF10536.9 KFM78307.1 - 0.014 14.5 4.0 0.018 14.2 4.0 1.1 1 0 0 1 1 1 0 Plant mobile domain DUF728 PF05304.12 KFM78307.1 - 0.18 11.7 2.9 0.37 10.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF728) DDE_Tnp_4 PF13359.6 KFM78308.1 - 5.9e-21 74.8 0.0 8.1e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM78308.1 - 1.2e-05 25.0 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFM78308.1 - 0.1 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain WD40 PF00400.32 KFM78309.1 - 1.1e-08 35.5 5.0 6.6 7.8 0.0 7.8 7 0 0 7 7 7 3 WD domain, G-beta repeat FBA_1 PF07734.13 KFM78309.1 - 0.021 14.8 0.4 0.087 12.7 0.4 2.2 1 0 0 1 1 1 0 F-box associated Cytochrom_D1 PF02239.16 KFM78309.1 - 0.046 12.2 0.0 1.1 7.8 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain VID27 PF08553.10 KFM78309.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.6 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain RRM_1 PF00076.22 KFM78310.1 - 1.2e-13 50.6 0.0 2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KFM78310.1 - 0.063 13.2 0.5 0.29 11.1 0.5 1.9 1 1 1 2 2 2 0 RL domain FlxA PF14282.6 KFM78310.1 - 0.16 12.0 1.5 0.27 11.2 1.5 1.3 1 0 0 1 1 1 0 FlxA-like protein Nup35_RRM_2 PF14605.6 KFM78310.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif IMD PF08397.11 KFM78312.1 - 1.5e-25 89.9 5.1 2e-25 89.5 5.1 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_1 PF00018.28 KFM78312.1 - 8.7e-12 44.5 0.1 1.4e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM78312.1 - 1.4e-11 44.1 0.1 2.3e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM78312.1 - 9.6e-07 28.4 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 KFM78312.1 - 0.017 14.7 3.5 0.025 14.2 3.5 1.2 1 0 0 1 1 1 0 BAR domain CAP_N PF01213.19 KFM78312.1 - 1.5 8.2 3.7 0.76 9.2 0.2 2.1 2 1 1 3 3 3 0 Adenylate cyclase associated (CAP) N terminal IPK PF03770.16 KFM78313.1 - 1.3e-57 194.9 0.0 2e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase CUB PF00431.20 KFM78314.1 - 5.5e-143 467.7 5.7 4.2e-41 139.7 0.1 4.4 5 0 0 5 5 5 4 CUB domain FXa_inhibition PF14670.6 KFM78314.1 - 2.5e-17 62.8 30.4 1.7e-09 37.8 10.4 3.0 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFM78314.1 - 1.8e-12 47.2 29.9 3.8e-06 27.0 9.5 2.7 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 KFM78314.1 - 6.2e-10 38.8 6.5 1.4e-05 24.9 0.9 3.3 2 0 0 2 2 2 2 Complement Clr-like EGF-like CUB_2 PF02408.20 KFM78314.1 - 7e-05 22.6 3.4 0.14 11.9 0.0 4.0 4 0 0 4 4 4 2 CUB-like domain EGF_3 PF12947.7 KFM78314.1 - 0.0027 17.9 26.9 0.015 15.4 7.3 3.2 2 0 0 2 2 2 2 EGF domain EGF PF00008.27 KFM78314.1 - 0.005 17.1 29.3 0.049 13.9 8.2 3.1 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 KFM78314.1 - 0.061 14.0 18.8 0.46 11.2 4.4 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 KFM78314.1 - 0.11 12.9 19.4 0.19 12.0 4.0 2.9 2 0 0 2 2 2 0 Pvs28 EGF domain DUF4215 PF13948.6 KFM78314.1 - 3.5 8.1 17.3 3.1 8.3 0.7 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4215) DNA_Packaging PF11053.8 KFM78315.1 - 0.051 13.4 0.0 0.074 12.9 0.0 1.4 1 1 0 1 1 1 0 Terminase DNA packaging enzyme RRM_1 PF00076.22 KFM78317.1 - 1.9e-14 53.2 0.0 3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM78317.1 - 0.082 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SAD_SRA PF02182.17 KFM78318.1 - 7e-35 120.0 0.0 1.3e-34 119.1 0.0 1.5 2 0 0 2 2 2 1 SAD/SRA domain SSF PF00474.17 KFM78319.1 - 4.6e-36 124.6 28.9 6.8e-36 124.0 28.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family MACPF PF01823.19 KFM78321.1 - 0.0012 19.0 0.0 0.0033 17.5 0.0 1.8 1 0 0 1 1 1 1 MAC/Perforin domain 7TMR-HDED PF07697.11 KFM78321.1 - 0.055 13.6 0.0 0.47 10.5 0.0 2.0 1 1 1 2 2 2 0 7TM-HD extracellular GspL_C PF12693.7 KFM78321.1 - 0.11 12.4 0.0 1.2 9.0 0.0 2.4 3 0 0 3 3 3 0 GspL periplasmic domain Chalcone PF02431.15 KFM78321.1 - 0.15 11.5 0.1 14 5.0 0.0 2.2 2 0 0 2 2 2 0 Chalcone-flavanone isomerase MACPF PF01823.19 KFM78323.1 - 0.0021 18.2 0.1 0.0042 17.2 0.0 1.5 1 1 0 1 1 1 1 MAC/Perforin domain MACPF PF01823.19 KFM78326.1 - 6.7e-06 26.3 0.4 1.5e-05 25.2 0.3 1.7 1 1 0 1 1 1 1 MAC/Perforin domain DASH_Dam1 PF08653.10 KFM78326.1 - 0.05 13.4 0.1 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 DASH complex subunit Dam1 RhoGAP PF00620.27 KFM78328.1 - 2e-27 95.9 1.9 3.1e-27 95.3 0.0 2.3 3 0 0 3 3 3 1 RhoGAP domain Matrilin_ccoil PF10393.9 KFM78328.1 - 0.11 12.4 0.5 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Rxt3 PF08642.10 KFM78328.1 - 0.31 11.8 2.0 0.79 10.5 0.1 2.7 2 1 0 3 3 3 0 Histone deacetylation protein Rxt3 Takusan PF04822.13 KFM78328.1 - 0.88 9.5 6.3 0.11 12.4 0.3 2.7 3 0 0 3 3 3 0 Takusan DUF3800 PF12686.7 KFM78328.1 - 2.5 8.8 6.9 2.6e+02 2.3 0.0 4.0 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) PA PF02225.22 KFM78329.1 - 0.0071 16.3 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 PA domain CrgA PF06781.12 KFM78329.1 - 0.015 15.3 0.5 0.028 14.4 0.5 1.4 1 0 0 1 1 1 0 Cell division protein CrgA Asp5 PF17000.5 KFM78329.1 - 0.018 15.1 0.7 0.034 14.3 0.7 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 PspB PF06667.12 KFM78329.1 - 0.12 12.4 3.1 0.45 10.6 3.1 1.9 2 0 0 2 2 2 0 Phage shock protein B PGG PF13962.6 KFM78331.1 - 0.025 14.4 0.6 3.5 7.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function Tetraspanin PF00335.20 KFM78331.1 - 0.27 10.9 5.0 4.8 6.8 0.4 2.1 2 0 0 2 2 2 0 Tetraspanin family Gram_pos_anchor PF00746.21 KFM78331.1 - 0.74 9.8 2.0 27 4.8 0.2 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif ESSS PF10183.9 KFM78331.1 - 4.8 7.5 5.8 4.2 7.6 1.4 2.4 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ODV-E18 PF10717.9 KFM78332.1 - 0.098 12.5 0.1 0.098 12.5 0.1 3.1 2 1 2 4 4 4 0 Occlusion-derived virus envelope protein ODV-E18 DUF4064 PF13273.6 KFM78332.1 - 0.46 10.8 19.3 0.33 11.2 0.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF423 PF04241.15 KFM78332.1 - 1.5 9.1 5.0 0.91 9.8 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF423) DUF2157 PF09925.9 KFM78332.1 - 2.2 8.1 8.1 4.3 7.1 8.1 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) TMEM171 PF15471.6 KFM78332.1 - 4.2 6.3 12.1 1.1 8.2 8.5 1.9 1 1 1 2 2 2 0 Transmembrane protein family 171 Tetraspanin PF00335.20 KFM78332.1 - 8.4 6.0 21.1 0.091 12.5 11.7 1.9 1 1 1 2 2 2 0 Tetraspanin family Chromo PF00385.24 KFM78333.1 - 1.5e-12 47.2 0.8 2.6e-12 46.5 0.8 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 KFM78333.1 - 5.4e-12 45.2 4.1 1.1e-11 44.2 4.1 1.6 1 0 0 1 1 1 1 CBX family C-terminal motif Tudor-knot PF11717.8 KFM78333.1 - 0.0002 21.2 0.5 0.00041 20.2 0.5 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Ras PF00071.22 KFM78334.1 - 2.8e-06 27.0 0.2 4.3e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM78334.1 - 2.3e-05 24.6 0.2 3.4e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFM78334.1 - 0.0014 18.6 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KFM78334.1 - 0.0021 18.5 0.0 0.0023 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 KFM78334.1 - 0.0065 15.9 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 KFM78334.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PolyG_pol PF01518.16 KFM78334.1 - 0.024 13.3 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Sigma NS protein AAA_25 PF13481.6 KFM78334.1 - 0.031 13.9 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 KFM78334.1 - 0.051 12.7 0.0 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 KFM78334.1 - 0.073 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KFM78334.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFM78334.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KFM78335.1 - 7e-06 25.7 0.1 1.2e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM78335.1 - 1.2e-05 25.6 0.5 2e-05 24.8 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KFM78335.1 - 0.025 13.9 0.3 0.09 12.0 0.0 1.8 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 KFM78335.1 - 0.047 13.6 0.2 0.063 13.2 0.2 1.3 1 1 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KFM78335.1 - 0.054 13.0 0.3 0.12 11.9 0.1 1.5 1 1 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFM78335.1 - 0.079 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFM78335.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFM78335.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KFM78335.1 - 0.16 11.7 0.6 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ig_2 PF13895.6 KFM78337.1 - 1.1e-08 35.2 0.9 0.0041 17.4 0.0 4.0 3 2 1 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM78337.1 - 2.3e-08 34.0 0.0 0.0033 17.4 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM78337.1 - 1.1e-07 32.3 2.0 0.0038 17.8 0.0 4.1 3 2 1 4 4 4 2 Immunoglobulin domain V-set PF07686.17 KFM78337.1 - 0.0024 18.0 0.1 3.6 7.8 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 KFM78337.1 - 0.0041 17.2 0.1 30 4.9 0.0 3.9 4 0 0 4 4 4 1 Immunoglobulin domain I-set PF07679.16 KFM78337.1 - 0.025 14.6 0.0 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin I-set domain PP2C PF00481.21 KFM78338.1 - 2.4e-49 168.3 0.0 3.3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFM78338.1 - 4.6e-08 33.0 0.0 8.3e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C COesterase PF00135.28 KFM78339.1 - 5.6e-20 71.7 0.0 5.9e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF3299 PF11736.8 KFM78339.1 - 0.038 14.0 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) Integrase_H2C2 PF17921.1 KFM78340.1 - 0.00068 19.7 1.3 0.00079 19.5 0.5 1.6 2 0 0 2 2 2 1 Integrase zinc binding domain Chitin_bind_4 PF00379.23 KFM78341.1 - 5.8e-10 39.6 5.4 5.8e-10 39.6 5.4 2.5 2 1 0 2 2 2 1 Insect cuticle protein PIF3 PF05006.12 KFM78343.1 - 0.13 12.4 6.8 0.31 11.1 2.1 2.1 1 1 1 2 2 2 0 Per os infectivity factor 3 fn3 PF00041.21 KFM78346.1 - 1.7e-09 37.9 0.1 9.7e-08 32.3 0.1 2.2 2 0 0 2 2 2 1 Fibronectin type III domain Lectin_C PF00059.21 KFM78346.1 - 0.49 11.1 4.6 0.26 12.0 0.9 2.3 3 0 0 3 3 3 0 Lectin C-type domain Glyco_transf_54 PF04666.13 KFM78347.1 - 3.5e-59 200.1 5.1 4.7e-59 199.6 5.1 1.2 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.17 KFM78347.1 - 0.051 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) HPS3_Mid PF14762.6 KFM78348.1 - 2e-41 142.1 2.7 3.1e-41 141.4 2.7 1.3 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region GTP_EFTU PF00009.27 KFM78349.1 - 8.8e-31 107.0 0.1 8.8e-31 107.0 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFM78349.1 - 2.3e-18 66.3 0.1 2.3e-18 66.3 0.1 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 KFM78349.1 - 1.2e-14 53.9 0.0 3.4e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 KFM78349.1 - 2.1e-14 53.6 2.0 2.2e-09 37.6 0.1 3.8 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM78349.1 - 3.7e-05 23.8 0.0 3.7e-05 23.8 0.0 3.3 4 1 0 4 4 4 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFM78349.1 - 0.0013 18.6 1.2 0.0056 16.5 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Roc PF08477.13 KFM78349.1 - 0.002 18.3 0.3 0.0076 16.5 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase zf-C2H2 PF00096.26 KFM78350.1 - 7.3e-28 95.5 37.1 5.7e-05 23.3 1.0 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM78350.1 - 4.9e-25 86.8 36.0 3.7e-06 27.1 1.3 7.6 8 0 0 8 8 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM78350.1 - 2.5e-22 77.6 36.4 0.00052 20.6 0.9 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFM78350.1 - 8e-13 48.3 28.9 0.0078 16.6 0.1 6.7 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM78350.1 - 4.2e-11 42.8 19.8 0.094 13.0 0.5 6.5 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM78350.1 - 7.3e-09 35.4 29.0 0.012 15.6 0.4 6.5 6 0 0 6 6 6 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFM78350.1 - 0.00054 20.0 16.0 0.031 14.4 0.8 5.0 5 1 0 5 5 4 2 Zinc ribbon domain zf-Di19 PF05605.12 KFM78350.1 - 0.00062 20.0 25.4 0.085 13.2 2.1 4.4 2 2 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KFM78350.1 - 0.003 18.2 22.8 0.24 12.1 2.7 5.6 2 1 3 6 6 5 2 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 KFM78350.1 - 0.0052 16.8 16.3 2 8.5 0.8 5.2 1 1 2 3 3 3 1 CpXC protein GAGA PF09237.11 KFM78350.1 - 0.0065 16.2 10.1 0.43 10.4 0.1 4.2 3 1 1 4 4 4 1 GAGA factor HypA PF01155.19 KFM78350.1 - 0.0088 16.0 13.1 0.8 9.7 0.9 4.0 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 KFM78350.1 - 0.011 16.1 28.9 0.89 9.9 0.1 6.0 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KFM78350.1 - 0.024 14.7 25.0 0.65 10.2 4.0 3.9 1 1 1 3 3 3 0 FYVE zinc finger Sprouty PF05210.13 KFM78350.1 - 0.048 14.0 13.2 0.51 10.7 3.2 2.6 2 1 0 2 2 2 0 Sprouty protein (Spry) BolA PF01722.18 KFM78350.1 - 0.14 12.5 2.8 9.4 6.6 0.2 3.3 2 1 1 3 3 3 0 BolA-like protein Actin_micro PF17003.5 KFM78350.1 - 0.32 10.1 18.0 0.23 10.6 0.5 4.0 1 1 2 3 3 3 0 Putative actin-like family DUF3268 PF11672.8 KFM78350.1 - 0.35 11.2 5.6 2.7 8.3 0.2 2.8 3 0 0 3 3 3 0 zinc-finger-containing domain DUF2180 PF09947.9 KFM78350.1 - 0.36 10.9 12.1 0.24 11.4 0.2 3.3 3 1 0 3 3 2 0 Uncharacterized protein conserved in archaea (DUF2180) zinc_ribbon_15 PF17032.5 KFM78350.1 - 0.55 11.0 17.1 5.9 7.7 2.3 4.2 2 2 2 4 4 4 0 zinc-ribbon family Vps36-NZF-N PF16988.5 KFM78350.1 - 0.62 9.5 15.0 0.32 10.4 0.2 4.3 2 1 3 5 5 5 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PhnA_Zn_Ribbon PF08274.12 KFM78350.1 - 0.66 10.0 0.0 0.66 10.0 0.0 3.6 4 1 0 4 4 3 0 PhnA Zinc-Ribbon zf-FPG_IleRS PF06827.14 KFM78350.1 - 0.72 9.8 6.2 0.88 9.5 0.1 3.6 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-C2H2_11 PF16622.5 KFM78350.1 - 0.89 9.4 29.7 0.58 10.0 0.7 6.0 6 0 0 6 6 6 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KFM78350.1 - 1.2 8.8 16.8 0.31 10.7 0.2 5.7 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 KFM78350.1 - 1.2 9.5 15.6 0.89 9.8 1.4 4.6 2 1 1 4 4 4 0 TFIIH C1-like domain zf-AN1 PF01428.16 KFM78350.1 - 1.3 9.2 25.8 23 5.2 0.3 6.5 4 1 2 6 6 6 0 AN1-like Zinc finger zf-trcl PF13451.6 KFM78350.1 - 1.3 9.0 15.9 5.4 7.0 0.0 5.3 6 0 0 6 6 6 0 Probable zinc-ribbon domain Elf1 PF05129.13 KFM78350.1 - 1.8 8.7 26.0 0.82 9.8 3.3 5.4 2 1 4 6 6 6 0 Transcription elongation factor Elf1 like zf-FCS PF06467.14 KFM78350.1 - 2.1 8.4 15.5 1.5 8.8 0.5 5.0 4 1 1 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf-C2HE PF16278.5 KFM78350.1 - 2.2 8.8 33.3 2.3 8.7 1.6 6.2 1 1 5 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KFM78350.1 - 2.3 8.2 19.4 0.12 12.3 0.5 5.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Cript PF10235.9 KFM78350.1 - 3.2 8.4 18.0 0.62 10.7 1.1 4.2 3 1 2 5 5 3 0 Microtubule-associated protein CRIPT DZR PF12773.7 KFM78350.1 - 3.4 7.8 22.5 3 7.9 8.3 4.3 2 2 1 3 3 3 0 Double zinc ribbon zf-LYAR PF08790.11 KFM78350.1 - 3.8 7.5 12.2 0.44 10.5 0.2 4.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-nanos PF05741.13 KFM78350.1 - 5.5 7.3 18.9 17 5.7 0.1 5.1 5 1 0 5 5 4 0 Nanos RNA binding domain zf-piccolo PF05715.13 KFM78350.1 - 7.1 6.9 13.1 5.7 7.2 0.1 4.0 3 1 0 3 3 3 0 Piccolo Zn-finger RRM_1 PF00076.22 KFM78351.1 - 8.8e-18 63.9 0.1 1.6e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM78351.1 - 8.9e-05 22.5 0.4 0.00032 20.7 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 KFM78351.1 - 0.0031 17.1 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KFM78351.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 RL domain PEX11 PF05648.14 KFM78352.1 - 2.1e-64 217.0 1.9 2.4e-64 216.9 1.9 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) UBA_4 PF14555.6 KFM78353.1 - 1e-07 31.6 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain OTU PF02338.19 KFM78353.1 - 7.5e-06 26.5 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease TAP_C PF03943.13 KFM78353.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain OTU PF02338.19 KFM78354.1 - 2.6e-14 53.8 0.0 2.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Ribosomal_L34e PF01199.18 KFM78355.1 - 0.031 14.6 2.9 0.07 13.5 0.1 2.7 2 1 1 3 3 3 0 Ribosomal protein L34e zf-A20 PF01754.16 KFM78355.1 - 0.77 9.8 4.9 1.7 8.7 4.9 1.6 1 0 0 1 1 1 0 A20-like zinc finger adh_short PF00106.25 KFM78356.1 - 4.3e-27 94.8 0.1 6.2e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM78356.1 - 5.4e-17 62.1 0.0 9.3e-17 61.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM78356.1 - 2e-05 24.6 0.0 3.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 KR domain CAP_GLY PF01302.25 KFM78357.1 - 1.1e-15 57.3 0.5 2.1e-15 56.5 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain YajC PF02699.15 KFM78357.1 - 0.02 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit DivIC PF04977.15 KFM78357.1 - 0.043 13.6 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator MIF4G PF02854.19 KFM78360.1 - 1.5e-05 24.7 1.2 2.5e-05 24.0 1.2 1.4 1 1 0 1 1 1 1 MIF4G domain YlbD_coat PF14071.6 KFM78360.1 - 0.0091 16.2 0.2 0.014 15.6 0.2 1.3 1 0 0 1 1 1 1 Putative coat protein Cyclin_C PF02984.19 KFM78360.1 - 0.023 14.8 0.2 0.058 13.5 0.0 1.8 1 1 1 2 2 2 0 Cyclin, C-terminal domain IKI3 PF04762.12 KFM78360.1 - 0.064 11.2 0.2 0.076 11.0 0.2 1.0 1 0 0 1 1 1 0 IKI3 family TANGO2 PF05742.12 KFM78360.1 - 0.13 12.3 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 Transport and Golgi organisation 2 Laminin_G_1 PF00054.23 KFM78361.1 - 2.1e-83 277.0 0.1 3e-20 72.8 0.0 5.4 5 0 0 5 5 5 5 Laminin G domain Laminin_G_2 PF02210.24 KFM78361.1 - 3.7e-82 273.1 3.3 2.3e-18 67.0 0.0 5.6 6 0 0 6 6 6 5 Laminin G domain Laminin_EGF PF00053.24 KFM78361.1 - 1.4e-21 76.4 69.9 1.2e-07 31.7 19.6 5.0 5 0 0 5 5 5 4 Laminin EGF domain Laminin_I PF06008.14 KFM78361.1 - 2.6e-16 60.1 14.2 2.6e-16 60.1 14.2 3.7 2 1 0 3 3 3 1 Laminin Domain I Laminin_B PF00052.18 KFM78361.1 - 7.3e-09 35.6 0.1 2.6e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Laminin B (Domain IV) Laminin_II PF06009.12 KFM78361.1 - 4.6e-05 23.4 4.7 4.6e-05 23.4 4.7 4.5 3 1 2 5 5 5 1 Laminin Domain II Laminin_G_3 PF13385.6 KFM78361.1 - 0.0021 18.2 0.0 0.61 10.2 0.0 3.3 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily DUF4363 PF14276.6 KFM78361.1 - 0.56 10.4 4.7 0.78 9.9 0.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4363) DUF948 PF06103.11 KFM78361.1 - 1.7 9.0 15.2 9.4 6.6 0.4 5.4 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Laminin_B PF00052.18 KFM78362.1 - 9.7e-11 41.7 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_EGF PF00053.24 KFM78363.1 - 2.4e-86 283.7 203.6 2.4e-12 46.8 14.4 11.3 10 1 1 11 11 11 10 Laminin EGF domain Laminin_EGF PF00053.24 KFM78364.1 - 1.1e-23 83.1 80.4 5.2e-08 32.9 12.9 4.6 4 0 0 4 4 4 4 Laminin EGF domain Laminin_N PF00055.17 KFM78364.1 - 8.2e-08 32.1 0.1 8.2e-08 32.1 0.1 3.5 4 1 1 5 5 5 1 Laminin N-terminal (Domain VI) HMG_box PF00505.19 KFM78367.1 - 1.5e-27 95.8 4.0 2.1e-27 95.3 4.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM78367.1 - 2.3e-10 40.9 1.4 3.9e-10 40.2 1.4 1.3 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.8 KFM78367.1 - 8.1e-05 23.6 2.0 0.00011 23.2 0.6 2.0 2 0 0 2 2 2 1 SOX transcription factor Arena_nucleocap PF00843.17 KFM78368.1 - 0.03 13.2 0.0 0.05 12.5 0.0 1.3 1 1 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain AAA_25 PF13481.6 KFM78368.1 - 0.21 11.1 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain MIF4G_like_2 PF09090.11 KFM78369.1 - 0.011 15.3 0.3 0.024 14.1 0.3 1.6 1 0 0 1 1 1 0 MIF4G like DUF3322 PF11795.8 KFM78369.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) STAG PF08514.11 KFM78370.1 - 0.78 9.7 3.1 0.99 9.3 0.6 2.5 2 1 0 2 2 2 0 STAG domain RasGAP PF00616.19 KFM78371.1 - 1.5e-06 28.1 0.0 1.5e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP PF00616.19 KFM78372.1 - 6.1e-15 55.5 0.0 7e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Ets PF00178.22 KFM78373.1 - 6.5e-35 119.5 0.7 2.1e-34 117.8 0.7 1.9 1 0 0 1 1 1 1 Ets-domain eIF-3_zeta PF05091.12 KFM78373.1 - 0.052 12.5 11.8 0.073 12.0 11.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) LMBR1 PF04791.16 KFM78373.1 - 0.38 9.6 1.9 0.47 9.3 1.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CPSF100_C PF13299.6 KFM78373.1 - 0.49 10.6 5.6 0.87 9.8 5.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 KFM78373.1 - 0.62 9.0 11.7 0.91 8.5 11.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 KFM78373.1 - 1.2 7.9 15.4 1.7 7.3 15.4 1.1 1 0 0 1 1 1 0 Presenilin EPL1 PF10513.9 KFM78373.1 - 1.3 9.4 14.2 2.5 8.5 14.2 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like CLN3 PF02487.17 KFM78373.1 - 2.2 7.2 8.3 3.1 6.7 8.3 1.1 1 0 0 1 1 1 0 CLN3 protein Lin-8 PF03353.15 KFM78373.1 - 2.4 7.7 18.2 4.8 6.7 18.2 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 KFM78373.1 - 2.4 7.9 19.8 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Spt20 PF12090.8 KFM78373.1 - 2.4 7.7 36.9 4.7 6.7 36.9 1.5 1 0 0 1 1 1 0 Spt20 family Membralin PF09746.9 KFM78373.1 - 2.5 7.1 7.3 3.5 6.6 7.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Macoilin PF09726.9 KFM78373.1 - 3 6.3 17.1 4.5 5.7 17.1 1.2 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 KFM78373.1 - 3.6 5.6 12.0 4.8 5.2 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tim54 PF11711.8 KFM78373.1 - 4.6 5.9 11.7 7.4 5.3 11.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM60A PF15396.6 KFM78373.1 - 4.9 7.1 10.9 9.3 6.2 10.9 1.4 1 0 0 1 1 1 0 Protein Family FAM60A TERB2 PF15101.6 KFM78373.1 - 7.1 6.6 18.4 12 5.9 18.4 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ALMT PF11744.8 KFM78373.1 - 7.9 5.2 11.6 11 4.7 11.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1656 PF07869.12 KFM78380.1 - 0.07 13.2 8.3 0.29 11.2 3.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1656) Isochorismatase PF00857.20 KFM78382.1 - 1.1e-29 103.9 0.0 1.6e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family DUF2833 PF11090.8 KFM78382.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) Ig_3 PF13927.6 KFM78383.1 - 3.2e-14 53.3 0.0 3.1e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM78383.1 - 5.8e-14 51.9 0.0 7e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFM78383.1 - 2.4e-12 47.0 0.0 4.4e-06 26.8 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 KFM78383.1 - 4.2e-12 46.1 0.0 6.1e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM78383.1 - 2.9e-11 43.6 0.0 5.2e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 KFM78383.1 - 0.0029 17.2 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set_CD47 PF08204.11 KFM78383.1 - 0.0042 17.1 0.0 0.0083 16.1 0.0 1.6 1 1 0 1 1 1 1 CD47 immunoglobulin-like domain C1-set PF07654.15 KFM78383.1 - 0.0045 17.3 0.0 0.026 14.9 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 KFM78383.1 - 0.061 13.5 0.0 8.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFM78383.1 - 0.18 11.9 0.0 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Caudo_TAP PF02413.17 KFM78384.1 - 0.039 14.1 1.7 0.082 13.1 1.7 1.5 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK zf-C2H2 PF00096.26 KFM78385.1 - 1.2e-26 91.7 35.7 2.1e-05 24.7 1.1 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78385.1 - 3.5e-20 70.9 34.3 0.00025 21.6 0.9 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM78385.1 - 3.3e-19 68.4 38.7 1.5e-06 28.3 0.4 5.5 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM78385.1 - 4.7e-14 52.2 17.3 0.0023 18.2 0.2 5.3 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM78385.1 - 1.3e-11 44.2 29.8 0.00014 21.7 1.8 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM78385.1 - 1.1e-08 35.1 21.0 0.14 12.6 0.1 5.3 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM78385.1 - 0.032 14.0 1.1 0.032 14.0 1.1 5.2 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 KFM78385.1 - 0.047 14.4 1.5 0.047 14.4 1.5 3.0 2 1 1 3 3 2 0 zinc-ribbon family zf-C2HE PF16278.5 KFM78385.1 - 0.87 10.1 25.0 0.17 12.4 0.8 4.2 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 KFM78385.1 - 1.1 9.3 16.7 17 5.5 2.1 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 KFM78385.1 - 1.7 8.7 30.3 0.32 11.1 0.6 5.2 2 2 3 5 5 5 0 BED zinc finger zf-AN1 PF01428.16 KFM78385.1 - 2.2 8.5 26.3 23 5.3 0.1 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 KFM78385.1 - 3.7 7.8 21.0 2 8.6 0.3 4.4 1 1 4 5 5 5 0 Zinc ribbon domain ATPase-cat_bd PF12156.8 KFM78385.1 - 4.2 8.2 14.4 7.7 7.3 1.9 2.9 3 0 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase PyrI_C PF02748.15 KFM78385.1 - 5.9 6.9 20.6 15 5.6 3.4 4.9 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Jnk-SapK_ap_N PF09744.9 KFM78386.1 - 0.013 15.7 15.2 0.016 15.4 15.2 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 KFM78386.1 - 0.56 10.6 7.9 1.2 9.6 3.4 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF2570 PF10828.8 KFM78386.1 - 0.95 9.3 6.8 0.74 9.7 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) SR-25 PF10500.9 KFM78386.1 - 1.1 8.8 6.6 0.11 12.1 2.0 1.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF16 PF01519.16 KFM78386.1 - 2 8.9 11.9 0.54 10.8 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 KFM78386.1 - 2.7 5.8 7.4 3.3 5.5 7.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.21 KFM78386.1 - 3.9 7.7 12.2 0.19 11.9 4.6 2.4 1 1 0 2 2 2 0 bZIP transcription factor DUF5338 PF17273.2 KFM78387.1 - 0.048 13.7 0.0 0.058 13.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5338) AHSP PF09236.10 KFM78389.1 - 0.037 14.5 0.1 0.039 14.4 0.1 1.0 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein Ricin_B_lectin PF00652.22 KFM78392.1 - 2.6e-19 69.7 2.0 3.2e-19 69.4 2.0 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KFM78392.1 - 0.0079 16.9 0.6 0.32 11.8 0.1 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like TPT PF03151.16 KFM78393.1 - 2.3e-08 33.7 0.5 2.5e-08 33.6 0.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM78393.1 - 4.2e-07 30.2 9.2 4.6e-07 30.1 9.2 1.1 1 0 0 1 1 1 1 EamA-like transporter family PUNUT PF16913.5 KFM78393.1 - 0.0039 16.5 1.4 0.0048 16.2 1.4 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 KFM78393.1 - 0.0067 15.7 2.7 0.0073 15.6 2.7 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KFM78393.1 - 0.0094 15.2 0.8 0.011 14.9 0.8 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF2070 PF09843.9 KFM78393.1 - 0.057 11.7 3.0 0.059 11.6 3.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2614 PF11023.8 KFM78393.1 - 1.4 9.0 4.4 0.5 10.5 0.8 1.9 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF423 PF04241.15 KFM78393.1 - 2.6 8.3 5.8 14 5.9 1.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF423) Spc7 PF08317.11 KFM78395.1 - 3e-06 26.3 83.4 0.0082 15.1 20.6 4.6 1 1 4 5 5 5 5 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFM78395.1 - 0.0085 16.1 89.5 0.18 11.8 15.4 5.2 1 1 3 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-met PF12874.7 KFM78395.1 - 0.029 14.8 0.1 0.083 13.3 0.1 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM78395.1 - 0.085 13.2 0.2 0.24 11.7 0.2 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAS PF13851.6 KFM78395.1 - 7.2 5.9 78.9 0.037 13.4 14.7 4.6 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 KFM78395.1 - 8 5.9 79.5 0.046 13.3 20.5 3.6 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain FYVE PF01363.21 KFM78396.1 - 4.4e-20 71.6 12.0 2e-19 69.5 12.0 2.2 1 0 0 1 1 1 1 FYVE zinc finger YojJ PF10372.9 KFM78396.1 - 0.0013 18.8 0.3 0.0013 18.8 0.3 4.2 4 2 1 5 5 5 1 Bacterial membrane-spanning protein N-terminus CENP-F_leu_zip PF10473.9 KFM78396.1 - 0.0046 17.0 68.9 0.012 15.6 23.1 3.9 1 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KFM78396.1 - 0.015 15.5 57.7 0.71 10.1 17.9 4.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 KFM78396.1 - 0.02 15.0 8.3 0.02 15.0 8.3 4.9 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 KFM78396.1 - 0.045 13.3 54.4 0.36 10.4 16.5 4.4 1 1 1 2 2 2 0 Intermediate filament protein US22 PF02393.16 KFM78396.1 - 0.069 13.4 0.3 0.17 12.1 0.3 1.7 1 0 0 1 1 1 0 US22 like IBR PF01485.21 KFM78396.1 - 0.16 12.2 11.3 0.075 13.3 7.3 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain TACC_C PF05010.14 KFM78396.1 - 0.21 11.3 55.6 0.15 11.8 35.9 2.9 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 KFM78396.1 - 0.27 10.6 61.1 0.021 14.2 9.7 4.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Nsp1_C PF05064.13 KFM78396.1 - 0.99 9.2 42.2 0.061 13.1 5.4 5.2 3 2 1 5 5 5 0 Nsp1-like C-terminal region zf-ribbon_3 PF13248.6 KFM78396.1 - 1.4 8.4 7.6 0.11 12.0 1.5 2.3 1 1 1 2 2 2 0 zinc-ribbon domain zf-RING_5 PF14634.6 KFM78396.1 - 2 8.4 12.5 6.3 6.9 12.5 1.9 1 0 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 KFM78396.1 - 2.3 8.3 13.4 5.4 7.1 1.7 2.8 1 1 1 2 2 2 0 Double zinc ribbon DotU PF09850.9 KFM78396.1 - 2.4 7.9 8.6 0.24 11.1 2.6 2.4 2 1 0 2 2 2 0 Type VI secretion system protein DotU Spc7 PF08317.11 KFM78396.1 - 3.1 6.6 61.8 0.94 8.3 19.5 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein zf-RING_2 PF13639.6 KFM78396.1 - 3.4 8.1 10.8 9.6 6.6 10.8 1.8 1 0 0 1 1 1 0 Ring finger domain AAA PF00004.29 KFM78396.1 - 4.7 7.6 7.7 8.9 6.7 3.1 2.5 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ERM PF00769.19 KFM78396.1 - 6.5 6.5 57.3 0.096 12.5 13.5 3.5 1 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 KFM78396.1 - 8.5 6.4 36.0 0.13 12.3 2.4 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KFM78396.1 - 8.5 6.4 67.3 2.3 8.3 26.1 5.0 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein LTV PF04180.14 KFM78397.1 - 9e-12 45.4 20.5 2.7e-11 43.8 20.3 1.8 1 1 1 2 2 2 1 Low temperature viability protein EF-hand_7 PF13499.6 KFM78397.1 - 0.016 15.7 2.9 2.6 8.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair CGGC PF08821.11 KFM78397.1 - 0.17 12.1 0.6 0.39 10.9 0.1 1.9 2 0 0 2 2 2 0 CGGC domain YonK PF09642.10 KFM78397.1 - 2.1 8.5 7.5 6.8 6.9 0.5 3.8 3 1 0 3 3 3 0 YonK protein EF-hand_1 PF00036.32 KFM78397.1 - 2.4 7.9 9.4 0.86 9.3 1.3 2.9 2 0 0 2 2 2 0 EF hand HYLS1_C PF15311.6 KFM78400.1 - 1.9e-10 41.3 0.5 4.3e-10 40.2 0.5 1.6 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus F-box-like PF12937.7 KFM78401.1 - 1.3e-16 60.2 2.5 2.7e-16 59.2 1.6 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFM78401.1 - 4.4e-14 51.9 1.1 1.2e-13 50.5 1.1 1.8 1 0 0 1 1 1 1 F-box domain Hemerythrin PF01814.23 KFM78401.1 - 4.2e-06 27.4 4.5 0.00067 20.3 0.2 2.3 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain F-box_4 PF15966.5 KFM78401.1 - 0.04 13.8 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 F-box PRANC PF09372.10 KFM78401.1 - 0.049 14.0 3.4 0.061 13.7 0.0 2.7 3 0 0 3 3 3 0 PRANC domain FAM47 PF14642.6 KFM78401.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 FAM47 family F-box_5 PF18511.1 KFM78401.1 - 0.097 12.3 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 F-box WWE PF02825.20 KFM78401.1 - 3 8.5 6.8 2.6 8.7 1.9 2.8 3 0 0 3 3 3 0 WWE domain LRR_6 PF13516.6 KFM78402.1 - 1.2e-07 31.2 4.0 4.9e-05 23.0 0.1 4.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 KFM78402.1 - 0.0002 21.7 0.0 0.0021 18.4 0.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM78402.1 - 0.00097 19.4 5.5 3.2 8.7 0.2 4.3 3 1 0 3 3 3 2 Leucine Rich Repeat TPR_19 PF14559.6 KFM78403.1 - 1.3e-16 60.8 7.7 0.00012 22.5 0.5 6.7 5 2 3 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM78403.1 - 1.2e-12 47.9 25.9 2.3e-05 24.5 0.5 5.3 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFM78403.1 - 4.5e-09 35.7 28.2 0.0027 17.7 0.2 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM78403.1 - 1.1e-05 25.8 6.7 0.56 11.2 0.1 6.8 7 1 1 8 8 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM78403.1 - 1.5e-05 25.0 0.8 0.0026 17.9 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM78403.1 - 2e-05 25.1 3.6 0.43 11.3 0.0 6.3 5 2 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM78403.1 - 0.00012 21.8 3.5 0.42 10.8 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM78403.1 - 0.00045 20.2 9.4 0.9 9.9 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM78403.1 - 0.0012 18.6 24.6 0.0023 17.6 0.4 6.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM78403.1 - 0.0012 19.3 14.1 0.84 10.4 0.1 6.8 8 0 0 8 8 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM78403.1 - 0.0015 18.5 2.5 0.7 10.0 0.4 4.0 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KFM78403.1 - 0.0026 18.0 14.5 1.4 9.2 0.1 6.3 7 1 0 7 7 7 2 Tetratricopeptide repeat Mhr1 PF12829.7 KFM78403.1 - 0.074 13.2 0.9 0.38 10.9 0.0 2.6 4 0 0 4 4 3 0 Transcriptional regulation of mitochondrial recombination PPR PF01535.20 KFM78403.1 - 0.25 11.7 6.7 38 4.8 0.0 5.5 7 0 0 7 7 6 0 PPR repeat SRP_TPR_like PF17004.5 KFM78403.1 - 0.51 10.4 16.8 0.5 10.4 6.9 3.9 2 2 1 3 3 3 0 Putative TPR-like repeat TPR_10 PF13374.6 KFM78403.1 - 1.6 8.7 8.1 22 5.1 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM78403.1 - 6.8 7.3 11.3 3.6 8.2 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Aa_trans PF01490.18 KFM78404.1 - 2.4e-23 82.5 6.4 2.7e-23 82.3 6.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3586 PF12131.8 KFM78404.1 - 0.035 14.3 2.7 0.061 13.6 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Aa_trans PF01490.18 KFM78405.1 - 4.4e-16 58.6 9.9 5.1e-16 58.4 9.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM78405.1 - 1.1e-06 28.0 7.6 1.5e-06 27.5 7.6 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family F-box_5 PF18511.1 KFM78405.1 - 0.098 12.2 0.2 8.8 6.0 0.1 2.7 3 0 0 3 3 3 0 F-box WD40 PF00400.32 KFM78407.1 - 1.2e-13 51.2 11.2 0.0011 19.8 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat F-box-like PF12937.7 KFM78407.1 - 3.2e-06 26.9 0.0 7.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM78407.1 - 0.0012 18.7 0.2 0.0022 17.8 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFM78407.1 - 0.002 18.0 0.1 0.0035 17.2 0.1 1.4 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 KFM78407.1 - 0.013 14.8 0.5 0.082 12.2 0.2 2.5 2 1 0 2 2 2 0 WD40-like domain Fascin PF06268.13 KFM78410.1 - 1.1e-49 167.3 0.1 1.6e-28 99.1 0.1 2.1 2 0 0 2 2 2 2 Fascin domain FRG1 PF06229.12 KFM78410.1 - 1.7e-08 34.4 0.0 1.4e-07 31.4 0.0 2.1 1 1 1 2 2 2 1 FRG1-like domain RicinB_lectin_2 PF14200.6 KFM78410.1 - 1.6e-05 25.5 0.0 0.017 15.8 0.0 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF569 PF04601.13 KFM78410.1 - 0.0042 16.8 0.0 0.28 10.9 0.0 2.8 1 1 1 3 3 3 2 Domain of unknown function (DUF569) 7tm_1 PF00001.21 KFM78411.1 - 4.8e-45 153.9 17.8 6.5e-45 153.5 17.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM78411.1 - 3e-07 30.1 18.1 4.7e-07 29.4 18.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFM78411.1 - 0.00016 21.5 9.9 0.00024 21.0 9.9 1.2 1 0 0 1 1 1 1 Olfactory receptor DUF4010 PF13194.6 KFM78411.1 - 0.83 9.3 5.8 0.63 9.7 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Flavoprotein PF02441.19 KFM78412.1 - 1.1e-49 168.2 0.0 1.3e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein NDUF_B7 PF05676.13 KFM78413.1 - 1.6e-23 82.2 4.2 2e-23 81.9 4.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Sel1 PF08238.12 KFM78414.1 - 1.2e-56 187.8 48.8 6.9e-09 36.1 0.1 12.8 13 0 0 13 13 13 10 Sel1 repeat Flu_M1_C PF08289.11 KFM78414.1 - 0.074 13.3 0.1 0.4 10.9 0.1 2.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain BTAD PF03704.17 KFM78414.1 - 0.1 13.0 0.7 18 5.7 0.0 3.4 2 1 0 2 2 2 0 Bacterial transcriptional activator domain fn3_3 PF14686.6 KFM78414.1 - 0.79 9.5 5.2 0.28 11.0 1.2 2.3 3 0 0 3 3 3 0 Polysaccharide lyase family 4, domain II TPR_16 PF13432.6 KFM78414.1 - 7.7 7.3 16.9 28 5.5 0.1 5.9 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM78414.1 - 9.1 6.6 12.6 1.9 8.7 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat ubiquitin PF00240.23 KFM78415.1 - 0.0097 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFM78415.1 - 0.035 13.9 0.3 0.092 12.6 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ax_dynein_light PF10211.9 KFM78416.1 - 4.6e-18 65.8 2.0 5.6e-18 65.6 2.0 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain FPP PF05911.11 KFM78416.1 - 0.0055 15.0 5.4 0.0065 14.7 5.4 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF1640 PF07798.11 KFM78416.1 - 0.03 14.4 4.5 0.035 14.1 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) bZIP_1 PF00170.21 KFM78416.1 - 0.053 13.6 11.7 0.88 9.7 5.5 2.3 1 1 1 2 2 2 0 bZIP transcription factor RTBV_P46 PF06216.11 KFM78416.1 - 0.15 11.0 0.5 0.18 10.7 0.5 1.0 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein JIP_LZII PF16471.5 KFM78416.1 - 0.2 11.9 6.2 0.55 10.4 2.5 2.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Glyco_trans_1_2 PF13524.6 KFM78416.1 - 0.53 10.7 4.3 0.22 12.0 0.9 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Sema PF01403.19 KFM78417.1 - 5.5e-55 186.9 0.0 6.4e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Sema domain Talin_middle PF09141.10 KFM78418.1 - 2.6e-65 219.4 3.8 2.6e-65 219.4 3.8 8.2 4 2 0 5 5 5 2 Talin, middle domain FERM_M PF00373.18 KFM78418.1 - 8.8e-27 93.9 0.0 5.2e-26 91.4 0.0 2.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFM78418.1 - 1.2e-18 66.7 1.5 3.3e-18 65.4 1.5 1.8 1 0 0 1 1 1 1 FERM N-terminal domain I_LWEQ PF01608.17 KFM78418.1 - 5.5e-17 62.4 82.8 7.2e-05 23.1 9.1 10.1 4 2 5 10 10 10 6 I/LWEQ domain IRS PF02174.17 KFM78418.1 - 8.4e-05 22.4 0.0 0.00025 20.9 0.0 1.8 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Vinculin PF01044.19 KFM78418.1 - 0.00027 19.3 51.4 0.00037 18.9 0.6 5.2 1 1 2 4 4 4 3 Vinculin family ACBP PF00887.19 KFM78418.1 - 0.0043 17.2 0.0 0.027 14.7 0.0 2.5 1 0 0 1 1 1 1 Acyl CoA binding protein VBS PF08913.10 KFM78418.1 - 0.0066 16.9 1.0 0.0066 16.9 1.0 5.8 4 1 2 6 6 6 2 Vinculin Binding Site Med30 PF11315.8 KFM78418.1 - 0.42 10.8 10.7 1.6 8.9 0.1 4.5 4 0 0 4 4 4 0 Mediator complex subunit 30 SNAP-25 PF00835.19 KFM78419.1 - 6.5e-21 74.4 0.6 1.5e-20 73.3 0.6 1.6 1 0 0 1 1 1 1 SNAP-25 family SNARE PF05739.19 KFM78419.1 - 0.0016 18.4 2.5 0.012 15.6 0.0 3.0 4 0 0 4 4 4 1 SNARE domain DUF5089 PF17002.5 KFM78419.1 - 0.018 15.0 7.7 0.071 13.0 7.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 KFM78419.1 - 0.18 12.1 6.6 0.5 10.7 0.2 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF2730 PF10805.8 KFM78419.1 - 0.33 11.1 4.4 1.8 8.7 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) Atg14 PF10186.9 KFM78419.1 - 0.53 9.3 7.9 4.7 6.2 3.8 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 KFM78419.1 - 0.53 10.5 11.1 0.11 12.7 1.4 3.0 2 1 1 3 3 3 0 Haemolysin XhlA SOAR PF16533.5 KFM78419.1 - 0.55 10.2 0.1 0.55 10.2 0.1 2.9 3 1 0 3 3 3 0 STIM1 Orai1-activating region EMP24_GP25L PF01105.24 KFM78419.1 - 0.87 9.5 3.7 3 7.8 0.2 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.11 KFM78419.1 - 1.2 7.9 12.4 0.15 10.9 1.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Sec20 PF03908.13 KFM78419.1 - 2.2 8.3 5.1 0.46 10.4 0.3 2.1 2 1 0 2 2 2 0 Sec20 DUF1664 PF07889.12 KFM78419.1 - 3.2 7.8 7.0 4.7 7.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFM78419.1 - 4.6 7.7 14.1 4.3 7.8 0.9 3.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Peptidase_M3_N PF08439.10 KFM78420.1 - 0.28 11.5 3.8 1.1 9.5 3.8 2.2 1 0 0 1 1 1 0 Oligopeptidase F zf-H2C2_2 PF13465.6 KFM78423.1 - 5.6e-62 203.6 90.1 1.9e-07 31.2 1.0 12.1 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78423.1 - 1.4e-54 179.6 95.9 8.3e-08 32.3 1.2 11.6 12 0 0 12 12 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78423.1 - 3.4e-41 136.3 82.6 0.00012 22.6 2.6 11.4 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM78423.1 - 1.8e-24 85.2 67.1 0.00017 21.5 1.3 10.8 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM78423.1 - 5.3e-16 58.4 68.3 0.0077 16.5 0.5 11.1 8 3 2 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM78423.1 - 1.8e-15 56.7 89.9 0.014 15.7 1.4 11.7 12 1 1 13 13 11 8 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM78423.1 - 4.3e-13 48.8 64.4 0.006 16.3 0.1 11.7 11 1 0 11 11 11 7 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM78423.1 - 0.0019 18.0 39.9 1.1 9.2 0.1 9.5 10 0 0 10 10 10 2 zinc-finger of a C2HC-type C1_1 PF00130.22 KFM78423.1 - 0.0034 17.2 58.9 1.8 8.5 2.3 9.4 5 2 5 10 10 10 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.7 KFM78423.1 - 0.005 17.2 65.2 1.6 9.1 1.5 9.3 1 1 8 9 9 9 2 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM78423.1 - 0.035 14.1 1.8 0.035 14.1 1.8 6.6 4 2 2 6 6 6 0 Adenylate kinase, active site lid BolA PF01722.18 KFM78423.1 - 0.059 13.7 18.2 3 8.2 0.5 6.4 2 1 1 3 3 3 0 BolA-like protein zf-C2H2_11 PF16622.5 KFM78423.1 - 0.19 11.5 56.9 0.19 11.5 0.5 10.0 11 0 0 11 11 11 0 zinc-finger C2H2-type GAGA PF09237.11 KFM78423.1 - 0.24 11.3 18.9 4.7 7.1 0.1 6.4 3 3 3 6 6 6 0 GAGA factor zf-C2H2_3rep PF18868.1 KFM78423.1 - 1.1 9.9 41.2 0.96 10.1 1.5 7.3 2 1 3 6 6 6 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 KFM78423.1 - 1.2 9.0 38.7 21 5.1 0.1 9.4 5 4 5 10 10 10 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 KFM78423.1 - 2 8.5 70.2 0.37 10.9 2.2 9.1 2 1 7 9 9 9 0 BED zinc finger WD40_alt PF14077.6 KFM78424.1 - 0.00046 20.0 0.1 0.0012 18.7 0.1 1.8 1 1 0 1 1 1 1 Alternative WD40 repeat motif DASH_Dam1 PF08653.10 KFM78424.1 - 0.0073 16.1 1.4 0.018 14.8 1.4 1.8 1 1 0 1 1 1 1 DASH complex subunit Dam1 HAUS-augmin3 PF14932.6 KFM78424.1 - 0.012 15.2 1.8 0.014 15.0 1.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Dynactin_p22 PF07426.11 KFM78424.1 - 0.029 14.2 3.1 0.055 13.3 3.1 1.5 1 1 0 1 1 1 0 Dynactin subunit p22 DUF4446 PF14584.6 KFM78424.1 - 0.053 13.5 1.4 0.066 13.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Frankia_peptide PF14407.6 KFM78424.1 - 0.056 13.4 0.2 0.09 12.8 0.2 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF2109 PF09882.9 KFM78424.1 - 0.059 13.4 0.4 0.087 12.8 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) DUF1270 PF06900.11 KFM78424.1 - 0.13 12.7 2.0 0.23 11.9 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) Anophelin PF10731.9 KFM78424.1 - 0.41 10.5 2.2 0.61 10.0 2.2 1.5 1 1 0 1 1 1 0 Thrombin inhibitor from mosquito Methyltransf_23 PF13489.6 KFM78425.1 - 5.3e-06 26.4 0.0 6.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM78425.1 - 8.2e-05 22.4 0.0 0.00013 21.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM78425.1 - 0.0072 17.0 0.0 0.011 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFM78425.1 - 0.018 14.5 0.0 0.025 14.1 0.0 1.4 1 1 0 1 1 1 0 Histone methylation protein DOT1 N6_N4_Mtase PF01555.18 KFM78425.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 DNA methylase PrmA PF06325.13 KFM78425.1 - 0.036 13.5 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KFM78425.1 - 0.057 13.4 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KFM78425.1 - 0.087 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N2227 PF07942.12 KFM78425.1 - 0.13 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein TehB PF03848.14 KFM78425.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB RAWUL PF16207.5 KFM78426.1 - 1.9e-13 50.9 0.0 2.1e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFM78427.1 - 2.6e-16 59.2 11.0 4.2e-16 58.5 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM78427.1 - 6.2e-10 38.8 11.5 1.1e-09 38.0 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM78427.1 - 2.2e-09 37.5 9.3 3.6e-09 36.8 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM78427.1 - 3.5e-08 33.2 8.6 5.5e-08 32.6 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM78427.1 - 2.6e-06 27.4 8.8 5.3e-06 26.3 8.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM78427.1 - 8.2e-06 25.7 9.6 1.4e-05 24.9 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM78427.1 - 2.1e-05 24.6 8.5 3.9e-05 23.7 8.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFM78427.1 - 0.00015 21.5 6.1 0.00015 21.5 6.1 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KFM78427.1 - 0.00094 18.9 7.8 0.002 17.9 7.8 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KFM78427.1 - 0.0014 18.4 3.5 0.0024 17.7 3.5 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KFM78427.1 - 0.0018 18.5 7.9 0.0055 17.0 7.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-UDP PF14569.6 KFM78427.1 - 0.01 15.9 2.1 0.035 14.2 2.1 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_5 PF17121.5 KFM78427.1 - 0.049 13.5 7.9 0.21 11.5 7.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM78427.1 - 0.052 13.4 9.2 0.82 9.6 9.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFM78427.1 - 0.11 12.6 1.6 0.2 11.7 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KFM78427.1 - 0.32 11.2 6.8 0.58 10.3 6.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KFM78427.1 - 0.42 10.4 5.0 0.94 9.3 5.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 KFM78427.1 - 2.1 8.4 7.5 32 4.6 7.5 2.5 1 1 0 1 1 1 0 Double zinc ribbon LRR_6 PF13516.6 KFM78428.1 - 5.1e-06 26.1 7.2 0.01 15.8 0.1 3.7 4 0 0 4 4 4 2 Leucine Rich repeat EAV_GP5 PF15981.5 KFM78428.1 - 0.045 14.2 0.0 0.093 13.1 0.0 1.5 1 0 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus LRR_4 PF12799.7 KFM78428.1 - 0.14 12.6 0.6 0.14 12.6 0.6 2.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM78428.1 - 2 9.3 6.8 5.7 7.9 0.4 3.4 2 1 1 3 3 3 0 Leucine Rich Repeat G-alpha PF00503.20 KFM78430.1 - 1e-103 347.3 10.6 1.2e-103 347.1 10.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFM78430.1 - 8.6e-15 54.6 0.1 2.3e-11 43.4 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM78430.1 - 0.012 15.6 0.0 0.83 9.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 KFM78430.1 - 0.021 15.0 0.1 0.94 9.7 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KFM78430.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 KFM78430.1 - 0.13 11.8 0.3 1.3 8.5 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_M3 PF01432.20 KFM78431.1 - 5.7e-94 316.0 0.0 6.4e-94 315.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Tom37 PF10568.9 KFM78431.1 - 0.013 15.8 0.2 0.03 14.6 0.2 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Lyase_1 PF00206.20 KFM78432.1 - 3.5e-21 75.9 0.0 7.3e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KFM78432.1 - 2.1e-16 60.2 0.0 6.7e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.6 KFM78432.1 - 0.00078 19.9 0.1 0.0018 18.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4089) Cob_adeno_trans PF01923.18 KFM78432.1 - 0.093 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Cobalamin adenosyltransferase ExoD PF06055.12 KFM78432.1 - 0.21 10.9 0.0 0.44 9.9 0.0 1.5 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD TPR_2 PF07719.17 KFM78434.1 - 1e-15 56.5 29.2 0.0067 16.5 0.4 10.0 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFM78434.1 - 9.3e-12 45.3 17.1 0.00085 19.8 0.1 7.2 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM78434.1 - 1.9e-10 40.1 25.6 0.0034 17.1 0.5 8.1 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFM78434.1 - 1.2e-09 38.3 15.2 0.031 14.6 0.2 7.7 5 3 3 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM78434.1 - 2.7e-07 30.3 21.4 0.16 12.2 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM78434.1 - 1.7e-06 28.4 4.3 9.8 7.3 0.0 7.3 7 2 2 9 9 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM78434.1 - 5.3e-06 27.0 4.5 0.017 15.7 0.0 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM78434.1 - 7.2e-05 22.6 12.8 2.7 8.2 0.0 7.1 9 0 0 9 9 7 3 Tetratricopeptide repeat DUF285 PF03382.14 KFM78434.1 - 0.00013 21.7 0.4 0.00034 20.4 0.4 1.7 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 TPR_6 PF13174.6 KFM78434.1 - 0.00047 20.6 10.8 0.22 12.2 0.3 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM78434.1 - 0.0011 19.1 34.3 0.025 14.8 8.1 6.4 4 3 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KFM78434.1 - 0.0038 17.5 3.1 0.51 10.7 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat SLATT_1 PF18181.1 KFM78434.1 - 0.0042 17.0 0.9 0.011 15.6 0.9 1.7 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 1 PPR_2 PF13041.6 KFM78434.1 - 0.035 14.3 10.8 25 5.2 0.3 6.4 7 1 1 8 8 7 0 PPR repeat family DUF4807 PF16065.5 KFM78434.1 - 0.098 12.3 0.4 3.4 7.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4807) TPR_11 PF13414.6 KFM78434.1 - 0.1 12.3 6.7 0.16 11.7 0.0 4.3 4 0 0 4 4 4 0 TPR repeat DUF4810 PF16068.5 KFM78434.1 - 0.2 12.3 10.6 2.9 8.5 0.1 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4810) PPR PF01535.20 KFM78434.1 - 0.53 10.7 12.5 32 5.1 0.1 6.7 7 0 0 7 7 6 0 PPR repeat TPR_10 PF13374.6 KFM78434.1 - 0.82 9.6 11.3 33 4.5 0.0 7.0 9 0 0 9 9 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM78434.1 - 1.6 8.9 10.1 0.2 11.7 1.3 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat MAS20 PF02064.15 KFM78434.1 - 2.1 8.5 8.5 18 5.5 0.0 3.7 3 0 0 3 3 3 0 MAS20 protein import receptor DUF4817 PF16087.5 KFM78436.1 - 1.4e-13 50.4 1.3 2.5e-13 49.6 1.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_29 PF13551.6 KFM78436.1 - 0.00013 21.9 0.4 0.03 14.3 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn helix HTH_32 PF13565.6 KFM78436.1 - 0.00058 20.4 1.1 0.0009 19.8 1.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFM78436.1 - 0.0076 16.4 1.7 2.5 8.3 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain bZIP_Maf PF03131.17 KFM78437.1 - 2.3e-25 88.9 11.7 3e-25 88.5 11.7 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFM78437.1 - 9.3e-06 25.6 14.3 3.8e-05 23.7 14.3 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM78437.1 - 0.001 19.1 6.9 0.001 19.1 6.9 1.9 1 1 1 2 2 2 1 Basic region leucine zipper DUF5320 PF17253.2 KFM78437.1 - 0.018 16.1 1.2 0.026 15.6 1.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF416 PF04222.12 KFM78437.1 - 0.047 13.1 0.7 0.058 12.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) SpmSyn_N PF17950.1 KFM78437.1 - 0.19 11.9 2.0 0.54 10.5 0.8 1.9 1 1 1 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal TBCA PF02970.16 KFM78437.1 - 0.3 11.5 7.2 0.68 10.3 7.2 1.5 1 1 0 1 1 1 0 Tubulin binding cofactor A Iron_permease PF04120.12 KFM78437.1 - 1.4 8.7 5.0 2.7 7.8 0.4 2.1 1 1 1 2 2 2 0 Low affinity iron permease V_ATPase_I PF01496.19 KFM78437.1 - 2.7 5.8 6.1 3.4 5.4 6.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 KFM78437.1 - 3.1 8.3 12.7 19 5.8 7.3 2.2 1 1 1 2 2 2 0 Cell division protein ZapB UPF0242 PF06785.11 KFM78437.1 - 4.7 7.3 10.8 8.8 6.4 10.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PMM PF03332.13 KFM78438.1 - 1.6e-99 332.2 0.9 1.8e-99 332.0 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KFM78438.1 - 4.8e-08 33.1 0.0 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM78438.1 - 0.021 15.1 0.0 0.048 13.9 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFM78438.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF600 PF04634.12 KFM78438.1 - 0.089 12.8 0.1 0.4 10.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF600 DIX PF00778.17 KFM78439.1 - 3.7e-28 97.2 0.1 7.8e-28 96.1 0.1 1.6 1 0 0 1 1 1 1 DIX domain Axin_b-cat_bind PF08833.10 KFM78439.1 - 1.3e-13 50.8 0.3 5.6e-13 48.8 0.3 2.2 1 0 0 1 1 1 1 Axin beta-catenin binding domain RGS PF00615.19 KFM78439.1 - 2.3e-13 50.5 0.2 1e-12 48.4 0.1 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain JAMP PF05571.12 KFM78440.1 - 2.3e-49 168.6 12.0 2.5e-49 168.5 12.0 1.0 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein JAMP PF05571.12 KFM78441.1 - 5.7e-26 91.8 2.1 6.2e-26 91.7 2.1 1.0 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein ArfGap PF01412.18 KFM78442.1 - 0.00019 21.5 0.2 0.00037 20.5 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf C2 PF00168.30 KFM78444.1 - 2.1e-15 56.9 0.0 6.6e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 C2 domain AATF-Che1 PF13339.6 KFM78444.1 - 0.018 15.8 0.9 0.07 13.8 0.3 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor C1_1 PF00130.22 KFM78445.1 - 7.2e-11 41.8 10.7 1.1e-10 41.2 10.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFM78445.1 - 0.0014 18.9 5.9 0.0027 18.0 5.9 1.5 1 0 0 1 1 1 1 C1 domain Zf_RING PF16744.5 KFM78445.1 - 0.016 15.3 5.2 0.033 14.3 5.2 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger OrfB_Zn_ribbon PF07282.11 KFM78445.1 - 0.1 12.5 4.3 0.25 11.3 4.3 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PHD PF00628.29 KFM78445.1 - 0.28 11.1 8.2 0.71 9.8 8.2 1.7 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_recom PF13408.6 KFM78445.1 - 0.74 10.4 10.5 1.8 9.2 10.5 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain HA2 PF04408.23 KFM78446.1 - 1.3e-20 73.7 0.0 1.3e-20 73.7 0.0 5.0 5 2 0 5 5 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFM78446.1 - 8.7e-14 51.8 0.0 2.2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFM78446.1 - 9.9e-14 51.5 0.0 5.3e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFM78446.1 - 1.8e-06 27.9 0.7 4.2e-06 26.6 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFM78446.1 - 1.1e-05 25.7 0.1 3.4e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM78446.1 - 0.00025 21.4 0.0 0.00062 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFM78446.1 - 0.00036 19.7 0.1 0.00081 18.5 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KFM78446.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 KFM78446.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM78446.1 - 0.0092 16.1 0.2 0.15 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KFM78446.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Microtub_bd PF16796.5 KFM78446.1 - 0.019 14.9 0.8 0.074 13.0 0.3 2.3 2 0 0 2 2 2 0 Microtubule binding AAA_7 PF12775.7 KFM78446.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KFM78446.1 - 0.07 13.2 0.3 0.57 10.2 0.3 2.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFM78446.1 - 0.15 11.8 0.1 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.19 KFM78446.1 - 0.18 11.4 0.3 0.48 10.0 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KFM78446.1 - 0.66 10.5 0.0 0.66 10.5 0.0 2.9 3 0 0 3 3 3 0 ABC transporter ECH_1 PF00378.20 KFM78447.1 - 1.7e-48 165.1 0.0 3.1e-48 164.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM78447.1 - 4.7e-31 108.5 0.0 2.3e-27 96.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4460 PF14687.6 KFM78448.1 - 3.1e-20 72.3 0.4 4.3e-20 71.8 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 KFM78449.1 - 2.3e-75 254.3 0.0 2.5e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) PH PF00169.29 KFM78450.1 - 9.7e-19 67.8 0.3 1.4e-18 67.3 0.3 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM78450.1 - 0.00014 22.2 0.2 0.00022 21.6 0.2 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain Anillin PF08174.11 KFM78451.1 - 1.6e-27 96.6 0.0 6.1e-27 94.8 0.0 2.1 1 0 0 1 1 1 1 Cell division protein anillin Anillin_N PF16018.5 KFM78451.1 - 6e-05 23.6 0.6 6e-05 23.6 0.6 3.9 4 1 1 5 5 5 1 Anillin N-terminus Lipase_GDSL PF00657.22 KFM78452.1 - 0.00015 21.8 0.0 0.00031 20.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF5398 PF17376.2 KFM78452.1 - 0.0068 17.0 0.0 3.8 8.2 0.0 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5398) ubiquitin PF00240.23 KFM78453.1 - 0.00033 20.3 0.0 0.00038 20.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family MG2 PF01835.19 KFM78457.1 - 1.6e-06 28.5 0.0 0.00025 21.4 0.0 2.1 2 0 0 2 2 2 2 MG2 domain Methyltransf_PK PF05891.12 KFM78457.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase A2M_BRD PF07703.14 KFM78458.1 - 4.2e-25 88.7 0.3 5.8e-25 88.3 0.3 1.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFM78459.1 - 3.2e-16 58.9 0.0 5e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-2-macroglobulin family Ldl_recept_a PF00057.18 KFM78459.1 - 5.9e-06 26.4 6.4 8.8e-06 25.8 6.4 1.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TED_complement PF07678.14 KFM78460.1 - 2.3e-13 49.9 0.1 2.5e-13 49.7 0.1 1.0 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 KFM78461.1 - 2.2e-06 28.3 0.0 4.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain DDE_1 PF03184.19 KFM78462.1 - 5.9e-07 29.3 0.0 7.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Hydrolase_4 PF12146.8 KFM78465.1 - 3.7e-15 55.9 0.0 2.9e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM78465.1 - 6.8e-08 33.4 0.1 1.3e-05 25.9 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM78465.1 - 1.4e-06 28.1 0.1 0.05 13.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KFM78465.1 - 1.1e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFM78465.1 - 6.6e-05 22.5 0.0 0.014 14.9 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KFM78465.1 - 0.00023 20.8 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFM78465.1 - 0.00051 19.9 0.0 0.0038 17.1 0.0 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DUF818 PF05677.12 KFM78465.1 - 0.00059 18.9 0.1 0.00082 18.4 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 KFM78465.1 - 0.0025 17.5 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) UPF0227 PF05728.12 KFM78465.1 - 0.058 13.3 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) LIP PF03583.14 KFM78465.1 - 0.061 12.6 0.1 0.12 11.7 0.0 1.4 2 0 0 2 2 2 0 Secretory lipase Asp2 PF16929.5 KFM78465.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Abhydrolase_4 PF08386.10 KFM78465.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein DuoxA PF10204.9 KFM78466.1 - 2.9e-34 118.4 1.8 3.2e-34 118.2 1.8 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor DUF441 PF04284.13 KFM78466.1 - 0.0025 17.9 1.2 0.0034 17.4 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF441) Vma12 PF11712.8 KFM78466.1 - 0.15 12.1 2.6 0.22 11.6 2.6 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DDE_1 PF03184.19 KFM78468.1 - 0.041 13.6 0.2 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease EF-hand_7 PF13499.6 KFM78469.1 - 0.00025 21.4 0.6 0.00073 19.9 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFM78469.1 - 0.017 15.0 1.5 0.063 13.2 0.5 2.5 2 0 0 2 2 2 0 EF-hand domain IRF-3 PF10401.9 KFM78469.1 - 0.095 12.5 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Interferon-regulatory factor 3 Ribosomal_L32p PF01783.23 KFM78470.1 - 8.2e-06 26.0 0.7 1.3e-05 25.3 0.7 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family DNA_RNApol_7kD PF03604.13 KFM78470.1 - 0.0035 17.0 1.1 1.9 8.2 0.1 2.4 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit DUF4428 PF14471.6 KFM78470.1 - 0.016 15.1 1.0 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DUF35_N PF12172.8 KFM78470.1 - 0.045 13.6 0.6 0.059 13.3 0.6 1.2 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PEHE PF15275.6 KFM78471.1 - 4.4e-13 50.0 0.2 4.4e-13 50.0 0.2 3.7 3 0 0 3 3 3 1 PEHE domain PMC2NT PF08066.12 KFM78471.1 - 0.68 10.7 5.6 0.47 11.2 0.6 3.4 3 0 0 3 3 3 0 PMC2NT (NUC016) domain VWC PF00093.18 KFM78472.1 - 0.00033 20.9 15.3 0.00036 20.8 15.3 1.1 1 0 0 1 1 1 1 von Willebrand factor type C domain Amnionless PF14828.6 KFM78472.1 - 0.025 13.4 14.7 0.026 13.4 14.7 1.0 1 0 0 1 1 1 0 Amnionless zf-3CxxC PF13695.6 KFM78473.1 - 1.3e-06 28.8 5.4 1.3e-06 28.8 5.4 1.5 2 0 0 2 2 2 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 KFM78473.1 - 0.019 15.7 14.9 5.5 7.8 13.6 3.2 1 1 1 2 2 2 0 Zinc-binding domain Gal_Lectin PF02140.18 KFM78475.1 - 1e-19 70.7 1.5 1e-19 70.7 1.5 1.6 2 0 0 2 2 2 1 Galactose binding lectin domain HRM PF02793.22 KFM78475.1 - 0.00023 21.4 4.5 0.00023 21.4 4.5 2.7 3 0 0 3 3 3 1 Hormone receptor domain WD40 PF00400.32 KFM78476.1 - 1.7e-51 171.0 17.6 6.8e-07 29.9 0.0 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM78476.1 - 1.1e-21 76.9 0.5 0.0078 16.5 0.1 7.6 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM78476.1 - 1e-12 48.4 0.2 0.0066 16.3 0.0 4.6 2 1 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFM78476.1 - 6.5e-07 29.0 0.0 3.8e-05 23.2 0.0 3.3 3 1 2 5 5 5 1 WD40-like domain Ge1_WD40 PF16529.5 KFM78476.1 - 1e-06 28.0 1.0 0.27 10.2 0.0 5.1 4 1 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFM78476.1 - 0.00023 21.0 2.2 9.2 6.3 0.0 5.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KFM78476.1 - 0.0056 16.1 0.2 22 4.2 0.0 4.5 4 1 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.7 KFM78476.1 - 0.011 15.6 0.9 14 5.5 0.1 4.0 3 2 0 3 3 3 0 Transcription factor IIIC subunit delta N-term RAB3GAP2_N PF14655.6 KFM78476.1 - 0.013 14.8 0.0 26 3.9 0.0 3.4 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_3 PF15911.5 KFM78476.1 - 0.029 14.4 0.0 1.4 9.0 0.0 3.8 3 2 2 5 5 5 0 WD domain, G-beta repeat Helveticin_J PF17312.2 KFM78476.1 - 0.085 11.9 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 Bacteriocin helveticin-J IKI3 PF04762.12 KFM78476.1 - 0.13 10.3 0.5 21 3.0 0.0 3.3 3 1 1 4 4 4 0 IKI3 family Nup160 PF11715.8 KFM78476.1 - 0.13 10.9 4.1 4.8 5.7 0.1 4.2 3 1 2 5 5 5 0 Nucleoporin Nup120/160 I-set PF07679.16 KFM78477.1 - 7.9e-27 93.2 0.0 1.7e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM78477.1 - 4e-24 85.0 0.0 6.4e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM78477.1 - 1.2e-15 57.4 0.0 5.6e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM78477.1 - 1.8e-14 53.8 0.0 4.5e-06 26.9 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM78477.1 - 7.2e-05 22.9 0.0 0.015 15.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM78477.1 - 0.00032 20.7 0.1 0.4 10.8 0.0 2.8 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain PDZ PF00595.24 KFM78480.1 - 2.4e-12 47.0 0.0 4.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM78480.1 - 2.1e-06 27.5 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM78480.1 - 2.2e-05 24.7 0.0 5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFM78480.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Otopetrin PF03189.13 KFM78482.1 - 1.1e-05 24.4 1.6 1.5e-05 24.1 0.7 1.6 2 0 0 2 2 2 1 Otopetrin Otopetrin PF03189.13 KFM78483.1 - 5.1e-132 440.9 24.2 5.7e-132 440.7 24.2 1.0 1 0 0 1 1 1 1 Otopetrin DUF4149 PF13664.6 KFM78483.1 - 0.038 14.3 2.8 0.35 11.2 1.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Otopetrin PF03189.13 KFM78484.1 - 2.3e-09 36.6 1.0 2.4e-09 36.5 1.0 1.0 1 0 0 1 1 1 1 Otopetrin MFS_1 PF07690.16 KFM78485.1 - 1.3e-28 100.0 14.8 8.4e-17 61.1 10.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFM78485.1 - 2.4e-09 37.0 6.6 2.4e-09 37.0 6.6 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KFM78485.1 - 0.00078 18.4 5.3 0.00078 18.4 5.3 1.6 2 0 0 2 2 2 1 MFS_1 like family ATG22 PF11700.8 KFM78485.1 - 0.0071 15.0 9.0 0.0067 15.1 7.9 1.6 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like Tom6 PF17112.5 KFM78485.1 - 0.82 9.2 6.2 0.32 10.5 1.9 2.6 2 1 1 3 3 3 0 Mitochondrial import receptor subunit Tom6, fungal CbtA PF09490.10 KFM78485.1 - 1.8 8.3 4.7 2.7 7.7 3.6 1.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Sdh_cyt PF01127.22 KFM78486.1 - 2e-26 92.4 3.6 2.5e-26 92.1 3.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit HABP4_PAI-RBP1 PF04774.15 KFM78487.1 - 3.2e-22 79.5 10.6 3.2e-22 79.5 10.6 3.8 3 2 0 3 3 3 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 KFM78487.1 - 2.1e-14 54.5 15.6 2.1e-14 54.5 15.6 2.9 1 1 1 3 3 3 1 Intracellular hyaluronan-binding protein 4 N-terminal DTC PF18102.1 KFM78488.1 - 1.5e-55 187.0 0.0 3.3e-55 185.9 0.0 1.6 1 0 0 1 1 1 1 Deltex C-terminal domain WWE PF02825.20 KFM78488.1 - 3.1e-34 117.4 0.1 2.4e-17 63.3 0.1 2.7 2 0 0 2 2 2 2 WWE domain zf-C3HC4 PF00097.25 KFM78488.1 - 1.5e-05 24.8 6.8 3.3e-05 23.6 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM78488.1 - 1.5e-05 25.2 5.6 3.1e-05 24.2 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFM78488.1 - 0.00078 19.4 3.6 0.0018 18.3 3.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFM78488.1 - 0.001 19.3 4.4 0.0027 18.0 4.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM78488.1 - 0.0019 18.1 5.9 0.0038 17.2 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM78488.1 - 0.038 13.8 9.3 0.17 11.8 9.3 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KFM78488.1 - 0.063 13.2 5.9 0.16 11.8 5.9 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_11 PF17123.5 KFM78488.1 - 0.21 11.3 4.4 0.74 9.6 4.4 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 KFM78488.1 - 3.6 7.7 10.9 0.077 13.1 3.8 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger NAD_binding_1 PF00175.21 KFM78489.1 - 2.7e-05 24.8 0.0 5.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFM78489.1 - 0.00027 21.1 0.0 0.00046 20.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KFM78489.1 - 0.0059 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain An_peroxidase PF03098.15 KFM78490.1 - 3.5e-156 520.9 0.0 4.7e-156 520.5 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Ferric_reduct PF01794.19 KFM78490.1 - 5.4e-18 65.3 10.2 1.4e-17 64.0 10.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFM78490.1 - 8.3e-17 61.7 0.0 1.7e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFM78490.1 - 7.6e-15 54.9 0.0 2.1e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain EF-hand_1 PF00036.32 KFM78490.1 - 2.3e-14 51.8 12.4 7.9e-07 28.2 0.9 4.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFM78490.1 - 1.6e-12 47.6 10.5 9.2e-07 29.2 0.6 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM78490.1 - 6.2e-11 41.3 5.0 8.1e-06 25.4 0.1 3.9 4 0 0 4 4 3 2 EF-hand domain EF-hand_5 PF13202.6 KFM78490.1 - 6.2e-10 38.1 3.2 1.4e-05 24.4 0.3 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFM78490.1 - 9.6e-06 25.4 11.3 0.0013 18.5 0.6 3.5 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM78490.1 - 0.11 12.9 1.2 0.89 9.9 0.4 3.0 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFM78490.1 - 0.59 10.1 5.0 32 4.5 0.3 3.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DEP PF00610.21 KFM78491.1 - 1.4e-15 57.1 0.3 3.8e-15 55.7 0.1 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TrmO PF01980.16 KFM78492.1 - 6e-44 149.1 0.0 9.6e-44 148.4 0.0 1.3 1 0 0 1 1 1 1 tRNA-methyltransferase O DUF5089 PF17002.5 KFM78492.1 - 0.029 14.2 2.0 0.062 13.2 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) U83 PF17465.2 KFM78492.1 - 0.05 13.7 0.0 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Chemokine-like protein, HHV-6 U83 gene product YabA PF06156.13 KFM78492.1 - 0.065 13.9 1.0 0.17 12.6 1.0 1.7 1 0 0 1 1 1 0 Initiation control protein YabA P66_CC PF16563.5 KFM78493.1 - 5.9e-14 51.4 13.6 5.9e-14 51.4 13.6 2.1 2 0 0 2 2 2 1 Coiled-coil and interaction region of P66A and P66B with MBD2 Ter PF05472.11 KFM78493.1 - 0.0034 16.5 0.0 0.027 13.5 0.0 2.1 2 0 0 2 2 2 1 DNA replication terminus site-binding protein (Ter protein) GATA PF00320.27 KFM78493.1 - 0.062 12.9 0.8 0.18 11.4 0.8 1.9 1 0 0 1 1 1 0 GATA zinc finger DUF503 PF04456.12 KFM78493.1 - 0.17 11.7 0.3 0.62 10.0 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF503) DUF1178 PF06676.11 KFM78493.1 - 0.37 11.2 3.6 0.18 12.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) GPP34 PF05719.11 KFM78494.1 - 6.7e-30 104.7 0.6 7e-30 104.6 0.6 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) CPG4 PF15481.6 KFM78498.1 - 0.00014 22.4 4.8 0.0025 18.4 5.1 2.3 1 1 1 2 2 2 2 Chondroitin proteoglycan 4 Sec16_C PF12931.7 KFM78498.1 - 0.075 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 PA28_beta PF02252.18 KFM78498.1 - 0.14 11.8 0.2 11 5.7 0.1 2.2 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit CotJB PF12652.7 KFM78498.1 - 0.5 10.6 2.7 15 5.9 0.3 2.7 3 0 0 3 3 3 0 CotJB protein RGM_N PF06535.12 KFM78498.1 - 0.66 10.2 6.2 1.2 9.3 6.2 1.6 1 1 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus Cobalamin_bind PF01122.19 KFM78501.1 - 4.1e-21 75.2 3.9 1.3e-20 73.6 3.9 1.7 1 1 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF4430 PF14478.6 KFM78501.1 - 0.0039 17.8 4.8 0.0098 16.5 1.7 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4430) AIDA PF16168.5 KFM78501.1 - 0.0044 17.1 0.0 0.0098 16.0 0.0 1.6 1 0 0 1 1 1 1 Adhesin of bacterial autotransporter system, probable stalk BRICHOS PF04089.14 KFM78502.1 - 0.00091 19.4 0.1 0.0024 18.1 0.1 1.9 2 1 0 2 2 2 1 BRICHOS domain IlvGEDA_leader PF08046.11 KFM78503.1 - 0.27 10.7 2.7 0.36 10.3 2.7 1.2 1 0 0 1 1 1 0 IlvGEDA operon leader peptide Peptidase_M28 PF04389.17 KFM78504.1 - 5.4e-28 98.0 0.3 7.4e-27 94.3 0.3 2.1 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFM78504.1 - 1.9e-06 27.7 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KFM78504.1 - 0.038 13.5 0.0 0.092 12.2 0.0 1.6 2 0 0 2 2 2 0 Nicastrin Peptidase_M42 PF05343.14 KFM78504.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase BAF250_C PF12031.8 KFM78505.1 - 5e-105 350.4 0.4 7.8e-105 349.8 0.4 1.3 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 KFM78505.1 - 5.9e-17 62.1 0.0 1.7e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BEN PF10523.9 KFM78506.1 - 5.7e-06 26.5 0.6 2.7e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 BEN domain Tnp_P_element PF12017.8 KFM78508.1 - 3e-14 53.0 0.2 4.6e-14 52.4 0.2 1.4 1 1 0 1 1 1 1 Transposase protein Pox_RNA_Pol_19 PF05320.12 KFM78508.1 - 0.039 13.9 0.4 0.067 13.2 0.4 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Telethonin PF09470.10 KFM78508.1 - 0.041 13.8 0.1 0.09 12.7 0.0 1.5 1 1 0 1 1 1 0 Telethonin protein Ribosomal_S11 PF00411.19 KFM78509.1 - 0.13 12.6 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S11 C2 PF00168.30 KFM78510.1 - 5.2e-20 71.7 0.0 8.6e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 KFM78510.1 - 2.4e-11 43.3 0.1 4.5e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM78510.1 - 6.4e-10 39.3 0.1 1.2e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM78510.1 - 0.057 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Co_AT_N PF12557.8 KFM78511.1 - 0.16 11.9 3.0 0.38 10.7 3.0 1.6 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Adaptin_N PF01602.20 KFM78512.1 - 1.5e-70 238.2 0.6 1.8e-70 238.0 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFM78512.1 - 2.6e-12 47.1 0.5 4.6e-12 46.3 0.1 1.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM78512.1 - 0.0028 18.0 0.1 4.8 7.6 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats API5 PF05918.11 KFM78512.1 - 0.021 13.7 0.4 4.3 6.0 0.0 2.1 1 1 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) RIX1 PF08167.12 KFM78512.1 - 0.043 13.5 0.2 1.1 8.9 0.2 2.4 1 1 0 1 1 1 0 rRNA processing/ribosome biogenesis adh_short PF00106.25 KFM78513.1 - 1.4e-34 119.3 0.4 2.2e-34 118.7 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM78513.1 - 8e-32 110.7 0.7 1.1e-31 110.2 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 KFM78513.1 - 1.1e-24 86.8 0.0 2.3e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KFM78513.1 - 0.00016 21.9 0.0 0.00034 20.9 0.0 1.6 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal KR PF08659.10 KFM78513.1 - 0.00022 21.2 0.1 0.00046 20.2 0.0 1.5 2 0 0 2 2 2 1 KR domain BON PF04972.17 KFM78513.1 - 0.056 13.8 0.3 0.19 12.1 0.1 1.9 2 0 0 2 2 2 0 BON domain Ank_2 PF12796.7 KFM78514.1 - 3.2e-33 114.1 5.3 1.9e-18 66.8 0.2 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM78514.1 - 2.5e-27 94.9 5.7 2.8e-10 40.5 0.0 4.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFM78514.1 - 4.5e-25 86.9 1.7 3.4e-07 30.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFM78514.1 - 6e-23 80.6 1.0 1.2e-08 35.1 0.2 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM78514.1 - 2.4e-22 76.6 2.3 1.5e-05 25.0 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat KN_motif PF12075.8 KFM78514.1 - 2.1e-08 33.8 0.2 5.1e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 KN motif Ribosomal_L6e PF01159.19 KFM78516.1 - 1.8e-28 99.3 1.9 1.8e-28 99.3 1.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KFM78516.1 - 1e-10 41.7 8.4 1e-10 41.7 8.4 2.9 3 1 1 4 4 4 1 Ribosomal protein L6, N-terminal domain ATP-synt_ab PF00006.25 KFM78517.1 - 7.6e-73 244.7 0.0 1.3e-72 243.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KFM78517.1 - 7.9e-46 155.5 1.0 1.4e-45 154.7 1.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KFM78517.1 - 3.1e-19 69.3 0.9 7.9e-19 67.9 0.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 KFM78517.1 - 0.037 14.2 0.6 0.084 13.0 0.6 1.6 1 0 0 1 1 1 0 HAS barrel domain HECT PF00632.25 KFM78518.1 - 2.1e-83 280.3 0.0 2.4e-83 280.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFM78519.1 - 1.8e-39 133.5 13.6 4.5e-14 52.2 2.3 4.4 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KFM78519.1 - 2.2e-25 88.9 0.0 5.5e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain CelD_N PF02927.14 KFM78519.1 - 0.12 13.2 0.6 21 6.1 0.0 3.0 2 1 0 2 2 2 0 Cellulase N-terminal ig-like domain TUG-UBL1 PF11470.8 KFM78520.1 - 2.4e-25 88.5 0.1 3.9e-24 84.6 0.1 2.5 2 0 0 2 2 2 1 TUG ubiquitin-like domain RBD PF02196.15 KFM78520.1 - 1.2e-06 28.5 0.0 3.9e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Raf-like Ras-binding domain RA PF00788.23 KFM78520.1 - 0.074 13.7 0.0 0.42 11.3 0.0 2.2 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain DUF5446 PF17522.2 KFM78520.1 - 7.9 6.7 9.1 0.5 10.6 1.5 2.7 3 1 0 3 3 3 0 Family of unknown function (DUF5446) Hexapep PF00132.24 KFM78522.1 - 5.4e-10 38.6 14.6 9.5e-06 25.1 3.5 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM78522.1 - 0.00018 21.2 8.1 0.015 15.1 0.4 3.8 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFM78522.1 - 0.0093 14.1 0.6 0.011 13.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KFM78522.1 - 0.0098 14.9 2.4 0.13 11.1 0.1 2.0 1 1 1 2 2 2 2 L-fucokinase Cytochrom_B559a PF00284.20 KFM78525.1 - 0.21 11.3 0.0 6.1 6.7 0.0 2.0 2 0 0 2 2 2 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Gaa1 PF04114.14 KFM78527.1 - 8e-103 345.1 1.8 1e-102 344.7 1.8 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF4040 PF13244.6 KFM78527.1 - 0.021 14.9 0.7 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) Paf67 PF10255.9 KFM78528.1 - 1.2e-172 574.4 6.2 1.6e-172 574.1 6.2 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.28 KFM78528.1 - 0.003 17.3 1.2 0.56 10.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM78528.1 - 0.0042 17.1 0.4 0.12 12.5 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM78528.1 - 0.11 12.7 0.6 0.4 10.9 0.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2428 PF10350.9 KFM78528.1 - 0.45 9.7 2.5 11 5.1 0.2 2.5 2 1 1 3 3 3 0 Putative death-receptor fusion protein (DUF2428) Formyl_trans_N PF00551.19 KFM78529.1 - 4.1e-44 150.5 0.0 5.8e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KFM78529.1 - 5.5e-09 36.2 0.0 1.2e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PP-binding PF00550.25 KFM78529.1 - 7.7e-07 29.4 0.1 2.3e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Aldedh PF00171.22 KFM78530.1 - 1.8e-173 577.3 0.0 2.1e-173 577.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFM78530.1 - 0.00012 21.6 0.0 0.00046 19.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) CUE PF02845.16 KFM78533.1 - 1.2e-08 34.4 0.1 3.3e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 CUE domain Glycos_transf_2 PF00535.26 KFM78534.1 - 2.5e-31 108.8 0.0 6e-31 107.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFM78534.1 - 8.7e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFM78534.1 - 0.00022 20.8 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFM78535.1 - 1.5e-35 122.5 0.0 2.6e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFM78535.1 - 3.9e-28 98.3 2.0 6.5e-28 97.5 2.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFM78535.1 - 1.5e-05 24.5 0.1 3.9e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 KFM78535.1 - 5.5e-05 23.2 0.0 9.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFM78535.1 - 0.0048 16.4 0.0 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 CDC24_OB2 PF17245.2 KFM78535.1 - 0.19 12.3 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 2 DUF4085 PF13315.6 KFM78537.1 - 0.22 11.1 6.9 2 8.0 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF4085) Ribosomal_60s PF00428.19 KFM78538.1 - 8.5e-16 58.3 1.1 9.9e-16 58.1 1.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein zf-H2C2_2 PF13465.6 KFM78539.1 - 6.5e-61 200.2 51.7 1.6e-09 37.7 0.3 9.8 10 0 0 10 10 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78539.1 - 2.9e-40 134.5 65.2 0.00014 22.1 1.5 9.2 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM78539.1 - 1.3e-30 104.7 47.7 0.00014 21.7 0.2 9.3 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFM78539.1 - 1.6e-30 103.2 58.2 0.0044 17.7 0.8 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFM78539.1 - 1.2e-12 47.9 25.4 0.0037 17.5 1.5 5.0 1 1 4 5 5 5 4 C2H2-type zinc ribbon zf-met PF12874.7 KFM78539.1 - 2.2e-11 43.8 51.9 0.1 13.0 1.1 9.4 9 0 0 9 9 9 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM78539.1 - 9.7e-11 41.7 40.7 0.058 13.7 0.1 9.2 7 2 2 9 9 9 5 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFM78539.1 - 2.7e-08 33.3 36.3 0.2 11.3 0.4 9.2 9 0 0 9 9 9 4 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM78539.1 - 2.7e-07 30.7 25.5 0.0037 17.3 5.1 3.9 1 1 2 3 3 3 3 Putative ribonucleoprotein zinc-finger pf C4 type ADK_lid PF05191.14 KFM78539.1 - 2.8e-06 27.2 33.2 0.063 13.3 3.9 6.6 5 2 2 7 7 7 4 Adenylate kinase, active site lid C1_1 PF00130.22 KFM78539.1 - 0.00024 20.9 40.4 0.69 9.9 1.4 8.0 4 3 3 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) HNH_5 PF14279.6 KFM78539.1 - 0.00077 19.3 40.4 0.81 9.6 1.9 7.6 5 4 1 6 6 6 3 HNH endonuclease zinc_ribbon_15 PF17032.5 KFM78539.1 - 0.002 18.8 28.6 1.2 9.9 1.3 4.9 1 1 5 6 6 6 3 zinc-ribbon family BolA PF01722.18 KFM78539.1 - 0.021 15.1 1.7 0.65 10.3 0.1 3.5 2 2 0 3 3 3 0 BolA-like protein Zn-ribbon_8 PF09723.10 KFM78539.1 - 0.034 14.3 28.3 0.77 9.9 1.3 6.4 1 1 7 8 8 8 0 Zinc ribbon domain zf-MYST PF17772.1 KFM78539.1 - 0.035 13.7 34.0 5.9 6.6 0.0 8.9 4 3 5 9 9 9 0 MYST family zinc finger domain DUF4428 PF14471.6 KFM78539.1 - 0.039 13.9 0.5 0.039 13.9 0.5 6.6 5 2 1 6 6 6 0 Domain of unknown function (DUF4428) zf_ZIC PF18366.1 KFM78539.1 - 0.063 13.4 37.5 5.2 7.3 0.8 7.7 3 1 6 9 9 8 0 Zic proteins zinc finger domain zf-RING_11 PF17123.5 KFM78539.1 - 0.074 12.8 18.1 6.2 6.7 0.1 5.5 6 0 0 6 6 5 0 RING-like zinc finger zf-FCS PF06467.14 KFM78539.1 - 0.2 11.6 30.8 8.5 6.4 0.1 7.9 6 2 3 9 9 9 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_9 PF16293.5 KFM78539.1 - 0.4 10.5 24.2 3.4 7.6 0.1 6.9 5 2 3 8 8 8 0 C2H2 type zinc-finger (1 copy) VATC PF18716.1 KFM78539.1 - 0.5 10.3 24.3 13 5.7 0.1 8.5 9 0 0 9 9 9 0 Vms1-associating treble clef domain Prok-RING_2 PF14445.6 KFM78539.1 - 0.61 10.3 21.6 24 5.2 0.0 8.1 8 1 1 9 9 9 0 Prokaryotic RING finger family 2 zf-C2H2_3rep PF18868.1 KFM78539.1 - 2.5 8.8 25.3 14 6.4 0.8 6.4 3 2 3 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-AN1 PF01428.16 KFM78539.1 - 2.9 8.1 46.9 4.3 7.6 1.1 9.0 7 1 2 9 9 9 0 AN1-like Zinc finger zf-C2H2_2 PF12756.7 KFM78539.1 - 7.8 6.9 42.5 26 5.2 0.3 7.0 1 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) Ribosomal_L18p PF00861.22 KFM78540.1 - 2.9e-05 24.4 0.1 3.7e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Abhydrolase_1 PF00561.20 KFM78541.1 - 5.7e-19 68.8 0.0 9.6e-19 68.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM78541.1 - 2.9e-12 47.7 0.0 5e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM78541.1 - 1.5e-07 30.9 0.0 3e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFM78541.1 - 0.00018 20.3 0.0 0.00022 20.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Lipase_3 PF01764.25 KFM78541.1 - 0.11 12.3 0.0 0.42 10.5 0.0 1.9 2 1 0 2 2 2 0 Lipase (class 3) Esterase PF00756.20 KFM78541.1 - 0.21 11.2 0.0 0.5 10.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Cpn60_TCP1 PF00118.24 KFM78542.1 - 1.7e-165 551.4 3.6 2e-165 551.1 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Abhydrolase_1 PF00561.20 KFM78543.1 - 2e-18 67.0 0.0 3.1e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM78543.1 - 1.8e-13 51.6 0.0 2e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM78543.1 - 1.1e-11 44.5 0.0 1.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFM78543.1 - 1.8e-05 23.6 0.0 0.00013 20.8 0.0 1.9 2 0 0 2 2 2 1 Ndr family Lipase_3 PF01764.25 KFM78543.1 - 6.2e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 KFM78543.1 - 8.9e-05 22.3 0.1 0.00027 20.7 0.1 1.7 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KFM78543.1 - 0.0029 17.4 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KFM78543.1 - 0.006 16.7 0.0 0.0087 16.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.11 KFM78543.1 - 0.023 14.0 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.11 KFM78543.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KFM78543.1 - 0.07 12.7 0.0 0.97 8.9 0.0 2.1 1 1 0 2 2 2 0 Dienelactone hydrolase family DUF2048 PF09752.9 KFM78543.1 - 0.083 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_5 PF12695.7 KFM78543.1 - 0.084 12.6 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family zf-H2C2_2 PF13465.6 KFM78544.1 - 2.5e-88 286.9 81.9 5.4e-09 36.1 0.3 14.3 14 0 0 14 14 14 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78544.1 - 2.5e-60 197.7 96.6 1.2e-06 28.6 0.9 13.4 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78544.1 - 1.6e-43 143.6 96.3 0.00029 21.4 0.5 13.7 14 0 0 14 14 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM78544.1 - 2.7e-23 81.6 101.0 0.0015 18.8 1.8 13.0 13 0 0 13 13 13 10 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM78544.1 - 3.9e-23 80.9 68.7 0.0049 16.6 1.3 13.5 13 0 0 13 13 13 12 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM78544.1 - 8.7e-12 45.0 72.8 0.38 11.1 0.3 13.0 12 1 0 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM78544.1 - 9.3e-10 38.3 84.3 0.028 14.4 0.4 14.3 14 0 0 14 14 14 7 C2H2-type zinc finger GAGA PF09237.11 KFM78544.1 - 7.8e-09 35.2 21.6 0.027 14.3 0.1 7.9 2 2 8 10 10 10 3 GAGA factor zf-C2H2_11 PF16622.5 KFM78544.1 - 1.8e-08 34.0 72.6 0.0032 17.2 0.9 11.7 12 0 0 12 12 12 4 zinc-finger C2H2-type Tox-HNH-HHH PF15637.6 KFM78544.1 - 1.2e-07 31.8 3.1 0.043 14.0 0.0 4.9 1 1 5 6 6 6 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF4825 PF16107.5 KFM78544.1 - 1.2e-07 31.8 3.3 5.2 7.3 0.0 8.3 1 1 9 10 10 10 1 Domain of unknown function (DUF4825) BolA PF01722.18 KFM78544.1 - 2.3e-05 24.6 21.6 5.6 7.3 0.3 8.8 2 2 6 8 8 8 1 BolA-like protein zf-MYST PF17772.1 KFM78544.1 - 2.7e-05 23.7 56.4 0.65 9.6 0.2 10.8 3 2 9 12 12 12 5 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 KFM78544.1 - 6.7e-05 22.9 31.5 19 5.4 0.1 9.9 8 2 2 10 10 10 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 KFM78544.1 - 0.0015 18.8 81.6 0.81 10.0 0.2 12.1 1 1 10 11 11 10 5 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KFM78544.1 - 0.0046 16.9 74.0 0.083 12.9 2.0 10.5 3 2 8 11 11 11 5 BED zinc finger zf-FPG_IleRS PF06827.14 KFM78544.1 - 0.0066 16.3 27.7 6.3 6.8 0.1 8.7 7 2 1 8 8 8 1 Zinc finger found in FPG and IleRS DUF2256 PF10013.9 KFM78544.1 - 0.011 15.8 32.2 18 5.5 0.1 9.7 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) Complex1_49kDa PF00346.19 KFM78544.1 - 0.19 10.8 6.9 1.4 7.9 0.3 3.8 1 1 2 4 4 4 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zinc_ribbon_15 PF17032.5 KFM78544.1 - 0.38 11.5 50.2 1.1 10.0 1.8 6.1 1 1 2 6 6 6 0 zinc-ribbon family Amidohydro_1 PF01979.20 KFM78544.1 - 0.6 9.4 6.7 18 4.5 0.1 4.3 1 1 2 5 5 5 0 Amidohydrolase family zf-trcl PF13451.6 KFM78544.1 - 3.9 7.4 34.2 13 5.8 0.1 9.2 9 0 0 9 9 9 0 Probable zinc-ribbon domain Mga PF05043.13 KFM78544.1 - 4.7 7.9 8.3 5.6 7.6 0.2 3.9 3 1 1 4 4 4 0 Mga helix-turn-helix domain Zn_ribbon_SprT PF17283.2 KFM78544.1 - 6 6.9 34.2 2.6 8.0 0.5 7.9 4 2 4 9 9 9 0 SprT-like zinc ribbon domain YtxC PF08812.11 KFM78544.1 - 6.1 6.4 7.4 0.74 9.4 0.2 2.7 3 1 1 4 4 4 0 YtxC-like family TB2_DP1_HVA22 PF03134.19 KFM78545.1 - 0.037 14.0 2.6 0.048 13.6 2.6 1.1 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Pkinase_Tyr PF07714.17 KFM78548.1 - 1.7e-86 289.7 0.0 2.1e-86 289.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM78548.1 - 2e-41 142.1 0.0 5.2e-41 140.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 KFM78548.1 - 0.021 14.7 0.6 0.042 13.8 0.6 1.4 1 0 0 1 1 1 0 TMEM154 protein family Haspin_kinase PF12330.8 KFM78548.1 - 0.031 13.2 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain EphA2_TM PF14575.6 KFM78548.1 - 0.068 14.1 0.0 0.14 13.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LAX PF15681.5 KFM78548.1 - 0.13 11.0 0.6 0.47 9.2 0.1 1.9 2 0 0 2 2 2 0 Lymphocyte activation family X Orf78 PF06024.12 KFM78548.1 - 0.17 12.2 0.4 0.32 11.3 0.4 1.4 1 0 0 1 1 1 0 Orf78 (ac78) PAS_11 PF14598.6 KFM78550.1 - 5e-17 62.1 0.1 1.8e-16 60.3 0.1 2.0 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KFM78550.1 - 6.2e-06 26.4 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KFM78550.1 - 0.00086 19.3 0.0 0.0029 17.6 0.0 1.8 2 0 0 2 2 2 1 PAS fold C1_1 PF00130.22 KFM78552.1 - 3.2e-12 46.1 5.8 4.7e-12 45.6 5.8 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1041 PF06292.17 KFM78554.1 - 2.1e-36 124.5 0.0 4.9e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) Membr_traf_MHD PF10540.9 KFM78555.1 - 3.3e-49 166.9 1.1 3.3e-49 166.9 1.1 2.0 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KFM78555.1 - 0.001 19.3 0.6 0.0024 18.2 0.4 1.8 2 0 0 2 2 2 1 C2 domain Mce4_CUP1 PF11887.8 KFM78555.1 - 0.065 12.7 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative HbrB PF08539.11 KFM78555.1 - 0.09 12.8 0.7 7.1 6.6 0.0 2.6 1 1 1 2 2 2 0 HbrB-like DUF3802 PF12290.8 KFM78555.1 - 0.14 12.7 0.7 1.3 9.6 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3802) LRR_8 PF13855.6 KFM78556.1 - 4.7e-52 173.6 61.2 4.7e-11 42.3 4.0 9.7 6 3 3 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KFM78556.1 - 1.3e-40 136.6 72.0 2.8e-06 27.6 2.8 12.2 6 2 11 18 18 18 15 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM78556.1 - 2.2e-10 40.3 25.3 0.042 13.4 1.0 5.6 1 1 1 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 KFM78556.1 - 2.1e-06 27.5 66.9 1.1 10.1 0.8 15.6 14 3 0 14 14 14 6 Leucine Rich Repeat LRR_6 PF13516.6 KFM78556.1 - 0.00058 19.7 45.8 3.4 7.9 0.2 12.8 15 0 0 15 15 15 3 Leucine Rich repeat DUF815 PF05673.13 KFM78556.1 - 0.12 11.5 0.4 7.1 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) PDZ PF00595.24 KFM78557.1 - 1.1e-08 35.3 0.2 1.1e-08 35.3 0.2 1.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM78557.1 - 3.3e-07 30.0 0.1 3.5e-07 30.0 0.1 1.0 1 0 0 1 1 1 1 PDZ domain Integrase_Zn PF02022.19 KFM78557.1 - 0.02 14.8 0.3 0.029 14.3 0.3 1.2 1 0 0 1 1 1 0 Integrase Zinc binding domain PDZ_2 PF13180.6 KFM78557.1 - 0.064 13.6 0.0 0.064 13.6 0.0 1.1 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 KFM78558.1 - 4.4e-15 55.8 1.1 1.4e-11 44.5 0.4 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM78558.1 - 2.3e-07 30.5 0.1 5.7e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM78558.1 - 0.07 13.5 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 KFM78559.1 - 0.16 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 PDZ domain Sulfatase PF00884.23 KFM78562.1 - 4e-45 154.5 0.0 9.3e-45 153.3 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFM78562.1 - 1.8e-09 37.6 0.0 3.1e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HTH_Tnp_Tc3_1 PF11427.8 KFM78562.1 - 0.081 12.8 0.3 1.5 8.7 0.1 2.2 2 0 0 2 2 2 0 Tc3 transposase Ribosomal_L22 PF00237.19 KFM78563.1 - 1.4e-44 150.5 0.3 1.8e-44 150.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e IP_trans PF02121.18 KFM78564.1 - 7e-45 153.5 0.1 7.6e-45 153.4 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein IP_trans PF02121.18 KFM78565.1 - 5.6e-65 219.4 0.3 6.3e-65 219.2 0.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Pro_isomerase PF00160.21 KFM78566.1 - 2.7e-53 180.5 3.5 5.1e-51 173.1 0.0 2.4 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 KFM78566.1 - 3.6e-09 36.4 0.9 3.6e-09 36.4 0.9 2.8 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KFM78566.1 - 0.0011 19.0 0.0 0.0031 17.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF3461 PF11944.8 KFM78566.1 - 0.021 15.0 7.0 0.13 12.3 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3461) U-box PF04564.15 KFM78566.1 - 0.027 14.6 0.0 0.092 12.9 0.0 1.9 1 0 0 1 1 1 0 U-box domain PTPRCAP PF15713.5 KFM78566.1 - 5.5 7.3 7.6 2.9 8.2 1.8 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated zf-H2C2_2 PF13465.6 KFM78567.1 - 4.4e-41 137.5 75.3 1.7e-06 28.2 1.7 11.3 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78567.1 - 2.2e-38 128.6 82.7 1.7e-05 25.0 3.5 11.4 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78567.1 - 8.4e-32 107.1 74.7 0.00097 19.8 0.6 11.3 11 0 0 11 11 11 9 C2H2-type zinc finger zf-met PF12874.7 KFM78567.1 - 2.2e-23 81.9 58.7 0.0086 16.4 0.7 9.9 9 0 0 9 9 9 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM78567.1 - 3.3e-10 40.0 44.2 0.065 13.5 0.4 9.5 8 1 1 9 9 9 6 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM78567.1 - 0.00036 20.7 3.1 2.6 8.4 0.0 5.2 2 2 1 3 3 3 1 BolA-like protein zf-C2H2_11 PF16622.5 KFM78567.1 - 0.0011 18.7 53.7 0.078 12.7 0.4 9.1 9 0 0 9 9 9 5 zinc-finger C2H2-type QSregVF PF13652.6 KFM78567.1 - 0.011 15.8 0.2 0.045 13.8 0.2 2.1 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Complex1_49kDa PF00346.19 KFM78567.1 - 0.018 14.2 0.3 2 7.4 0.0 2.6 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit GAGA PF09237.11 KFM78567.1 - 0.065 13.1 11.9 2 8.3 0.5 5.4 4 2 1 5 5 5 0 GAGA factor PAS_4 PF08448.10 KFM78567.1 - 0.53 10.6 4.6 70 3.7 0.0 5.1 3 1 1 4 4 4 0 PAS fold zinc_ribbon_15 PF17032.5 KFM78567.1 - 0.55 11.0 26.1 6.7 7.5 0.1 4.8 4 0 0 4 4 4 0 zinc-ribbon family zf-C2H2_6 PF13912.6 KFM78567.1 - 0.61 10.1 85.7 0.19 11.8 1.2 10.8 11 0 0 11 11 11 0 C2H2-type zinc finger DUF4028 PF13220.6 KFM78567.1 - 5.1 6.9 6.9 44 4.0 0.1 5.5 2 2 3 5 5 5 0 Protein of unknown function (DUF4028) DUF1043 PF06295.12 KFM78567.1 - 5.7 7.0 7.1 3.1 7.8 0.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Metal_resist PF13801.6 KFM78569.1 - 2.9 8.1 3.9 43 4.3 3.9 2.3 1 1 0 1 1 1 0 Heavy-metal resistance COesterase PF00135.28 KFM78571.1 - 5.3e-81 273.0 0.0 6.4e-81 272.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM78571.1 - 0.0013 18.6 0.1 0.0082 16.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFM78572.1 - 3.2e-27 95.6 0.0 3.8e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Ninjurin PF04923.12 KFM78572.1 - 0.0058 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Ninjurin T6SS_TssG PF06996.11 KFM78572.1 - 0.072 12.3 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion, TssG Sulf_transp PF04143.14 KFM78572.1 - 0.086 12.4 0.2 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Sulphur transport Cadherin_C_2 PF16492.5 KFM78572.1 - 0.1 13.4 1.3 0.26 12.0 1.3 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Aldedh PF00171.22 KFM78573.1 - 5.3e-187 621.9 0.0 6e-187 621.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BCNT PF07572.12 KFM78574.1 - 3.1e-22 78.4 4.3 3.1e-22 78.4 4.3 1.8 2 0 0 2 2 2 1 Bucentaur or craniofacial development zf-Tim10_DDP PF02953.15 KFM78575.1 - 1.7e-25 88.4 1.8 2.2e-25 88.1 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SRI PF08236.11 KFM78575.1 - 0.01 16.0 0.0 0.013 15.6 0.0 1.3 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain TAF4 PF05236.14 KFM78575.1 - 0.025 14.4 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TIL PF01826.17 KFM78575.1 - 0.057 13.7 0.5 0.085 13.1 0.5 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DUF1450 PF07293.11 KFM78575.1 - 0.088 12.6 1.4 1.1 9.1 0.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1450) MRP-L27 PF09809.9 KFM78576.1 - 1.2e-26 92.8 0.2 1.7e-26 92.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 PK PF00224.21 KFM78577.1 - 1.9e-160 533.4 5.0 2.8e-160 532.9 5.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFM78577.1 - 7.1e-33 113.3 0.2 2e-32 111.9 0.2 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFM78577.1 - 0.0067 15.6 1.2 0.012 14.8 0.2 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Pkinase_Tyr PF07714.17 KFM78578.1 - 1.8e-15 56.9 0.0 2.6e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 KFM78578.1 - 4.4e-15 54.8 0.7 9.8e-15 53.8 0.7 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase PF00069.25 KFM78578.1 - 5.9e-14 52.1 0.0 8.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Activin_recp PF01064.23 KFM78578.1 - 5.4e-11 43.4 9.3 1.1e-10 42.4 9.3 1.5 1 0 0 1 1 1 1 Activin types I and II receptor domain FTA2 PF13095.6 KFM78578.1 - 0.005 16.5 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DUF2735 PF10931.8 KFM78579.1 - 0.021 15.5 0.0 0.028 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) WH2 PF02205.20 KFM78580.1 - 2e-05 24.3 0.2 3.5e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 WH2 motif Reeler PF02014.16 KFM78581.1 - 1.8e-21 77.3 0.0 2.3e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Reeler domain WD40 PF00400.32 KFM78582.1 - 3.1e-13 50.0 8.2 0.0021 18.8 0.1 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM78582.1 - 0.00031 21.0 1.5 4.6 7.6 0.1 3.9 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFM78582.1 - 0.028 14.9 0.0 63 4.3 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Aminotran_1_2 PF00155.21 KFM78584.1 - 0.00052 19.3 0.0 0.00065 19.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 KFM78585.1 - 1e-11 44.6 0.0 1.2e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II 7tm_3 PF00003.22 KFM78586.1 - 1.2e-33 116.9 11.2 1.4e-33 116.6 11.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF3099 PF11298.8 KFM78586.1 - 0.18 12.0 1.8 0.33 11.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) RDD PF06271.12 KFM78586.1 - 7.4 6.8 9.9 0.29 11.3 1.1 2.4 2 1 0 2 2 2 0 RDD family VHL PF01847.16 KFM78588.1 - 2.3e-20 72.3 0.0 3.4e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 VHL beta domain VHL_C PF17211.3 KFM78588.1 - 3.4e-05 23.8 0.8 5e-05 23.2 0.1 1.7 2 0 0 2 2 2 1 VHL box domain SOCS_box PF07525.16 KFM78588.1 - 0.00042 20.6 0.1 0.0011 19.2 0.0 1.8 2 0 0 2 2 2 1 SOCS box WGR PF05406.15 KFM78589.1 - 5.2e-18 64.9 0.5 5.2e-18 64.9 0.5 1.8 2 0 0 2 2 2 1 WGR domain WWE PF02825.20 KFM78589.1 - 4.2e-16 59.3 4.4 1.7e-07 31.7 0.1 2.5 2 0 0 2 2 2 2 WWE domain ABC_membrane_3 PF13748.6 KFM78589.1 - 0.014 14.6 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region zf-RRN7 PF11781.8 KFM78589.1 - 0.38 10.5 3.4 0.79 9.5 3.0 1.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PARP PF00644.20 KFM78591.1 - 2.7e-52 177.2 0.0 3.6e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KFM78591.1 - 2.4e-34 118.4 0.2 3.4e-34 117.9 0.2 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Neur_chan_LBD PF02931.23 KFM78592.1 - 2.2e-46 158.0 0.1 2.7e-46 157.7 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM78592.1 - 1.9e-11 44.5 13.3 7.8e-10 39.2 6.5 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.6 KFM78592.1 - 0.42 8.4 0.3 0.59 8.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RasGEF_N PF00618.20 KFM78593.1 - 0.18 12.1 1.3 0.18 12.1 1.3 1.0 1 0 0 1 1 1 0 RasGEF N-terminal motif Neur_chan_LBD PF02931.23 KFM78594.1 - 3.1e-44 151.0 0.2 4.3e-44 150.6 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM78594.1 - 2e-11 44.4 9.6 4.1e-09 36.9 1.9 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFM78595.1 - 6.3e-49 166.3 0.7 9.2e-49 165.8 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM78595.1 - 5.1e-19 69.3 5.5 2.6e-15 57.1 2.1 2.4 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Wzy_C PF04932.15 KFM78595.1 - 0.01 15.5 2.6 0.37 10.4 0.8 2.2 2 0 0 2 2 2 0 O-Antigen ligase Neur_chan_memb PF02932.16 KFM78596.1 - 0.057 13.5 0.1 0.072 13.1 0.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GAPT PF11770.8 KFM78596.1 - 0.12 12.2 0.8 0.27 11.1 0.4 1.7 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) CBM_14 PF01607.24 KFM78597.1 - 5.8e-14 52.0 15.0 1.8e-08 34.4 3.8 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain CAF1A PF12253.8 KFM78597.1 - 0.024 14.8 0.7 0.024 14.8 0.7 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Neur_chan_LBD PF02931.23 KFM78599.1 - 1.4e-29 103.1 4.4 1.7e-29 102.8 4.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM78599.1 - 7.9e-26 91.6 4.4 1.1e-25 91.1 4.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2469 PF10611.9 KFM78599.1 - 0.081 13.5 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) zf-H2C2_2 PF13465.6 KFM78601.1 - 1.7e-12 47.2 6.4 1.2e-06 28.7 0.1 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78601.1 - 4.3e-10 39.5 10.3 8.4e-05 22.8 2.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM78601.1 - 1.7e-09 37.7 1.7 0.00063 20.0 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFM78601.1 - 1.9e-09 37.5 7.5 0.00027 21.5 0.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM78601.1 - 1e-06 28.9 8.2 0.0066 16.8 1.0 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM78601.1 - 5e-06 26.4 4.9 0.03 14.3 0.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM78601.1 - 0.0002 21.7 4.4 0.074 13.4 0.4 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFM78601.1 - 0.00026 20.7 1.4 0.2 11.5 0.1 2.0 1 1 1 2 2 2 2 GAGA factor zf-C2HE PF16278.5 KFM78601.1 - 0.00071 20.0 3.4 0.0075 16.7 0.2 2.1 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KFM78601.1 - 0.0012 18.6 3.8 0.29 10.9 0.4 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type LIM PF00412.22 KFM78601.1 - 0.0034 17.6 0.9 1 9.7 0.1 2.2 2 0 0 2 2 2 1 LIM domain Zf_RING PF16744.5 KFM78601.1 - 0.0036 17.4 2.5 0.96 9.6 0.2 2.1 1 1 1 2 2 2 2 KIAA1045 RING finger XPA_N PF01286.18 KFM78601.1 - 0.0043 17.1 0.2 1.7 8.7 0.0 2.2 2 0 0 2 2 2 1 XPA protein N-terminal HNH_5 PF14279.6 KFM78601.1 - 0.011 15.6 2.2 1.6 8.6 0.2 2.1 2 0 0 2 2 2 0 HNH endonuclease zf_ZIC PF18366.1 KFM78601.1 - 0.014 15.5 1.9 0.55 10.4 0.2 2.1 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-AN1 PF01428.16 KFM78601.1 - 0.021 15.0 5.5 0.44 10.7 0.5 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger Prok-RING_1 PF14446.6 KFM78601.1 - 0.022 14.7 0.6 6.6 6.7 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 BolA PF01722.18 KFM78601.1 - 0.024 14.9 0.1 0.13 12.6 0.0 1.9 1 1 1 2 2 2 0 BolA-like protein Baculo_IE-1 PF05290.11 KFM78601.1 - 0.025 14.5 0.8 0.24 11.3 0.8 1.9 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf_UBZ PF18439.1 KFM78601.1 - 0.027 14.1 0.7 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KFM78601.1 - 0.038 14.3 1.7 0.044 14.1 1.7 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KFM78601.1 - 0.064 13.4 2.0 2.8 8.1 1.9 2.1 1 1 1 2 2 2 0 Zinc ribbon domain DUF2225 PF09986.9 KFM78601.1 - 0.075 12.7 0.6 3.2 7.4 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_9 PF16293.5 KFM78601.1 - 0.1 12.5 0.6 8.1 6.4 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-LYAR PF08790.11 KFM78601.1 - 0.36 10.8 4.2 8.5 6.4 0.5 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF629 PF04780.12 KFM78601.1 - 0.44 9.0 5.1 3 6.3 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Actin_micro PF17003.5 KFM78601.1 - 0.66 9.1 3.6 7 5.7 3.6 1.9 1 1 0 1 1 1 0 Putative actin-like family zf-BED PF02892.15 KFM78601.1 - 0.67 10.0 8.7 2 8.5 0.8 2.2 1 1 1 2 2 2 0 BED zinc finger RNA_pol_Rpb1_1 PF04997.12 KFM78601.1 - 0.94 8.8 3.7 9.2 5.5 3.7 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 1 zf-H2C2_2 PF13465.6 KFM78602.1 - 1.3e-12 47.5 9.8 1.3e-06 28.6 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78602.1 - 1.1e-09 38.2 22.3 0.0008 19.7 2.4 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78602.1 - 4e-08 33.4 17.9 0.0033 18.1 1.7 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM78602.1 - 5.5e-06 26.5 12.4 0.036 14.4 0.1 3.2 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM78602.1 - 8.6e-05 22.2 2.7 8.6e-05 22.2 2.7 2.9 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-met PF12874.7 KFM78602.1 - 0.00016 21.9 17.5 0.022 15.1 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-AN1 PF01428.16 KFM78602.1 - 0.0091 16.1 8.4 0.64 10.2 0.5 3.1 3 0 0 3 3 3 2 AN1-like Zinc finger BolA PF01722.18 KFM78602.1 - 0.015 15.6 0.1 0.025 14.8 0.1 1.4 1 1 0 1 1 1 0 BolA-like protein zf-C2H2_3rep PF18868.1 KFM78602.1 - 0.015 16.0 2.1 0.4 11.3 0.6 2.6 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF2180 PF09947.9 KFM78602.1 - 0.026 14.5 1.5 0.17 11.9 0.6 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) FYVE_2 PF02318.16 KFM78602.1 - 0.06 13.6 4.7 0.17 12.1 0.7 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger Med13_C PF06333.12 KFM78602.1 - 0.073 12.3 0.1 0.077 12.2 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain LIM PF00412.22 KFM78602.1 - 0.12 12.6 7.8 9.3 6.6 0.3 3.0 2 1 0 2 2 2 0 LIM domain zf-C2H2_2 PF12756.7 KFM78602.1 - 0.17 12.2 10.7 5.4 7.4 0.3 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFM78602.1 - 0.24 11.9 10.5 1.6 9.3 0.8 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger HNH_5 PF14279.6 KFM78602.1 - 0.46 10.4 5.3 2.4 8.1 1.8 2.9 2 1 0 2 2 2 0 HNH endonuclease zf-C2H2_6 PF13912.6 KFM78602.1 - 0.47 10.5 16.7 0.18 11.8 1.7 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.12 KFM78602.1 - 0.75 9.8 7.4 48 4.0 7.4 2.6 1 1 0 1 1 1 0 zinc-ribbons zf-ZPR1 PF03367.13 KFM78602.1 - 1.5 8.6 5.1 1.5 8.6 1.3 2.0 1 1 1 2 2 2 0 ZPR1 zinc-finger domain DUF2197 PF09963.9 KFM78602.1 - 1.6 9.1 7.9 3.1 8.1 1.4 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-Di19 PF05605.12 KFM78602.1 - 1.7 9.0 10.3 0.091 13.1 3.2 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2757 PF10955.8 KFM78602.1 - 1.8 8.9 7.5 8.8 6.7 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2757) Copper-fist PF00649.18 KFM78602.1 - 1.8 8.1 8.2 4.3 6.9 0.6 2.9 3 0 0 3 3 3 0 Copper fist DNA binding domain zf_UBZ PF18439.1 KFM78602.1 - 2 8.0 7.2 9.8 5.9 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM78602.1 - 2.9 7.6 8.9 6 6.6 0.4 3.0 2 1 1 3 3 3 0 MYST family zinc finger domain zf-nanos PF05741.13 KFM78602.1 - 3.9 7.8 13.3 5.8 7.2 5.7 3.1 1 1 2 3 3 3 0 Nanos RNA binding domain zf-C2HC_2 PF13913.6 KFM78602.1 - 8 6.5 11.1 2 8.4 1.0 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type 7tm_1 PF00001.21 KFM78603.1 - 0.0016 17.9 5.0 0.0019 17.6 5.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) adh_short PF00106.25 KFM78604.1 - 5.8e-43 146.6 0.0 7.1e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM78604.1 - 1e-27 97.2 0.0 1.5e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM78604.1 - 0.0002 21.3 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFM78604.1 - 0.0016 17.9 0.0 0.0037 16.7 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KFM78604.1 - 0.17 11.3 0.0 0.41 10.1 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KFM78605.1 - 7.5e-08 32.1 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM78605.1 - 0.052 13.1 0.0 0.085 12.4 0.0 1.3 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM78606.1 - 0.00035 20.1 0.0 0.00041 19.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Acetyltransf_1 PF00583.25 KFM78607.1 - 1.5e-08 34.9 0.0 1.7e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM78607.1 - 0.00099 19.5 0.0 0.001 19.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF448 PF04296.13 KFM78607.1 - 0.0035 17.2 0.1 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF448) Acetyltransf_10 PF13673.7 KFM78607.1 - 0.082 12.8 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ChaC PF04752.12 KFM78609.1 - 4.7e-57 192.9 0.0 5.3e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 KFM78609.1 - 0.00012 22.7 0.0 0.00019 22.0 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Ras PF00071.22 KFM78610.1 - 6.4e-57 191.7 0.1 7.5e-57 191.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM78610.1 - 4.3e-20 72.1 0.0 6.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM78610.1 - 1.3e-10 41.0 0.0 1.5e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFM78610.1 - 1.2e-08 35.1 0.0 4.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFM78610.1 - 9e-06 25.4 0.0 3.5e-05 23.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM78610.1 - 0.0016 18.5 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KFM78610.1 - 0.018 14.3 0.0 0.89 8.8 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 KFM78610.1 - 0.022 14.3 0.0 0.031 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Arm PF00514.23 KFM78611.1 - 1.7e-26 91.4 2.8 2.8e-08 33.5 0.0 4.0 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFM78611.1 - 3.8e-06 27.3 0.2 0.00039 20.8 0.1 2.6 2 1 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.6 KFM78611.1 - 1.2e-05 25.6 0.5 0.0081 16.5 0.1 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KFM78611.1 - 0.0013 18.8 0.0 0.013 15.7 0.0 2.6 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 KFM78611.1 - 0.043 13.8 0.1 0.051 13.6 0.1 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Mesd PF10185.9 KFM78612.1 - 4.3e-07 30.0 1.9 6.1e-07 29.5 1.9 1.3 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor NAPRTase_N PF17767.1 KFM78613.1 - 1.1e-37 129.2 0.1 3.2e-37 127.7 0.0 1.9 2 1 1 3 3 3 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 KFM78613.1 - 3.9e-36 123.8 0.0 6.2e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 KFM78613.1 - 3.8e-12 46.3 0.0 2.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Ribosomal_L4 PF00573.22 KFM78614.1 - 3.1e-40 137.9 0.2 4.7e-40 137.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KFM78614.1 - 8e-23 80.3 6.0 8e-23 80.3 6.0 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DDE_3 PF13358.6 KFM78615.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.6 1 1 1 2 2 2 0 DDE superfamily endonuclease Nipped-B_C PF12830.7 KFM78619.1 - 6.5e-67 225.2 3.4 1.1e-64 217.9 0.3 3.3 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KFM78619.1 - 4.2e-14 52.5 6.8 9.6e-14 51.4 0.3 3.9 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KFM78619.1 - 1.7e-06 28.2 2.6 0.083 12.9 0.4 3.9 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFM78619.1 - 0.00051 20.1 1.2 3.6 8.1 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KFM78619.1 - 0.0011 19.4 0.8 8.6 7.0 0.0 4.5 3 1 1 4 4 4 2 HEAT-like repeat Cnd3 PF12719.7 KFM78619.1 - 0.11 11.7 13.1 0.29 10.3 0.0 5.2 5 2 1 6 6 6 0 Nuclear condensing complex subunits, C-term domain Homeodomain PF00046.29 KFM78620.1 - 6.1e-08 32.4 1.7 1.3e-07 31.4 1.7 1.5 1 0 0 1 1 1 1 Homeodomain PH_4 PF15404.6 KFM78620.1 - 0.073 12.9 4.0 0.096 12.5 4.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Rtf2 PF04641.12 KFM78620.1 - 0.19 11.0 6.5 0.25 10.7 6.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 KFM78620.1 - 0.63 8.7 7.3 0.71 8.6 7.3 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KFM78620.1 - 0.74 8.5 6.9 0.78 8.5 6.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4551 PF15087.6 KFM78620.1 - 0.82 8.4 8.2 0.96 8.2 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.9 KFM78620.1 - 0.96 7.9 10.6 0.97 7.9 10.6 1.0 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 KFM78620.1 - 1.8 7.4 5.5 1.9 7.4 5.5 1.0 1 0 0 1 1 1 0 Mitoguardin Menin PF05053.13 KFM78620.1 - 3.4 5.9 7.3 3.4 5.9 7.3 1.1 1 0 0 1 1 1 0 Menin zf-CCHC_3 PF13917.6 KFM78621.1 - 3.4e-08 33.3 0.0 6.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Zinc knuckle TFIIF_alpha PF05793.12 KFM78621.1 - 0.012 14.2 23.2 0.013 14.1 23.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Myosin_head PF00063.21 KFM78621.1 - 0.052 11.8 3.6 0.073 11.3 3.6 1.5 1 1 0 1 1 1 0 Myosin head (motor domain) zf-CCHC PF00098.23 KFM78621.1 - 0.096 12.8 3.9 0.19 11.9 3.9 1.5 1 0 0 1 1 1 0 Zinc knuckle SR-25 PF10500.9 KFM78621.1 - 0.099 12.2 31.7 0.12 11.9 31.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rtf2 PF04641.12 KFM78621.1 - 1.5 8.2 22.8 2.3 7.5 22.8 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.14 KFM78621.1 - 2.5 6.3 18.8 2.8 6.1 18.8 1.0 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 KFM78621.1 - 5.1 6.7 27.7 6.7 6.4 27.7 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 Neur_chan_memb PF02932.16 KFM78621.1 - 7.4 6.6 9.0 8.5 6.4 9.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3974 PF13120.6 KFM78622.1 - 0.053 13.6 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) SIKE PF05769.11 KFM78623.1 - 8.4e-65 218.1 29.6 1e-64 217.8 29.6 1.0 1 0 0 1 1 1 1 SIKE family DUF4188 PF13826.6 KFM78623.1 - 0.021 15.2 1.4 0.049 14.0 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4188) Glyco_hydro_17 PF00332.18 KFM78623.1 - 0.064 12.8 3.1 0.095 12.3 0.8 1.9 1 1 1 2 2 2 0 Glycosyl hydrolases family 17 DUF5094 PF17015.5 KFM78623.1 - 0.19 11.8 18.8 1.1 9.4 6.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) GM_CSF PF01109.17 KFM78623.1 - 0.46 10.6 5.0 5.5 7.2 0.6 2.9 1 1 1 2 2 2 0 Granulocyte-macrophage colony-stimulating factor DASH_Dam1 PF08653.10 KFM78623.1 - 4.2 7.2 6.2 1 9.2 0.4 2.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 Prominin PF05478.11 KFM78623.1 - 4.4 5.1 16.5 7.6 4.3 16.4 1.4 1 1 0 1 1 1 0 Prominin Syntaxin-6_N PF09177.11 KFM78623.1 - 4.4 7.9 19.6 8.1 7.1 5.3 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.11 KFM78623.1 - 6.6 7.1 9.2 1.1 9.6 1.5 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Med25_VWA PF11265.8 KFM78624.1 - 1.6e-94 315.7 0.0 4.9e-94 314.1 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit 25 von Willebrand factor type A Med25 PF11232.8 KFM78624.1 - 8e-44 149.3 0.1 8e-44 149.3 0.1 3.3 2 1 1 3 3 3 1 Mediator complex subunit 25 PTOV activation and synapsin 2 PP1c_bdg PF10488.9 KFM78625.1 - 3.5e-08 33.3 1.7 9.1e-08 31.9 0.0 2.3 2 0 0 2 2 2 1 Phosphatase-1 catalytic subunit binding region bZIP_Maf PF03131.17 KFM78625.1 - 0.044 14.3 4.8 0.11 13.0 4.8 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor BAR PF03114.18 KFM78626.1 - 4.2e-33 115.0 5.5 6.1e-33 114.5 5.5 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFM78626.1 - 1.4e-12 47.3 0.1 2.8e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM78626.1 - 2e-10 40.1 0.1 6.9e-10 38.4 0.1 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM78626.1 - 2.6e-08 33.4 0.0 6.8e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KFM78626.1 - 0.00018 21.3 5.3 0.00039 20.2 5.3 1.5 1 0 0 1 1 1 1 BAR domain of APPL family DUF4846 PF16138.5 KFM78626.1 - 0.012 15.2 0.2 0.031 13.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (4846) Arfaptin PF06456.13 KFM78626.1 - 0.013 15.1 6.0 0.47 10.0 0.3 2.2 2 0 0 2 2 2 0 Arfaptin-like domain EphA2_TM PF14575.6 KFM78627.1 - 0.17 12.8 0.5 9.6 7.2 0.1 2.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1751 PF08551.10 KFM78628.1 - 0.79 10.3 5.3 0.53 10.9 1.8 2.5 2 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DUF2967 PF11179.8 KFM78629.1 - 1.3 7.0 3.2 1.5 6.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Rad21_Rec8_N PF04825.13 KFM78630.1 - 8.8e-40 135.3 0.0 1.9e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KFM78630.1 - 2.5e-17 61.9 0.5 1.2e-16 59.7 0.1 2.2 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 KFM78630.1 - 1.5e-05 25.0 0.1 3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Segregation and condensation protein ScpA TraB PF01963.17 KFM78630.1 - 0.12 12.3 0.2 0.44 10.4 0.2 2.1 1 1 0 1 1 1 0 TraB family RabGAP-TBC PF00566.18 KFM78632.1 - 2.6e-21 76.3 1.8 2.6e-21 76.3 1.8 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ATG16 PF08614.11 KFM78632.1 - 0.00035 20.9 12.4 0.00058 20.2 12.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SlyX PF04102.12 KFM78632.1 - 0.00062 20.3 0.2 0.00062 20.3 0.2 3.1 2 1 1 3 3 3 1 SlyX APG6_N PF17675.1 KFM78632.1 - 0.0015 19.1 6.3 0.0029 18.1 6.3 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF1664 PF07889.12 KFM78632.1 - 0.0016 18.4 4.7 0.0016 18.4 4.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) ERM PF00769.19 KFM78632.1 - 0.0022 17.9 7.9 0.0028 17.5 7.9 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family GAS PF13851.6 KFM78632.1 - 0.0034 16.8 12.0 0.0034 16.8 12.0 2.1 2 1 1 3 3 2 1 Growth-arrest specific micro-tubule binding Cob_adeno_trans PF01923.18 KFM78632.1 - 0.004 17.3 1.5 0.0072 16.5 1.5 1.4 1 0 0 1 1 1 1 Cobalamin adenosyltransferase ADIP PF11559.8 KFM78632.1 - 0.0059 16.7 2.3 0.0059 16.7 2.3 2.2 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Prominin PF05478.11 KFM78632.1 - 0.014 13.3 4.8 0.022 12.7 4.8 1.3 1 0 0 1 1 1 0 Prominin AAA_13 PF13166.6 KFM78632.1 - 0.015 13.9 7.7 0.032 12.9 7.7 1.4 1 1 0 1 1 1 0 AAA domain FAM209 PF15206.6 KFM78632.1 - 0.017 14.9 0.7 0.03 14.1 0.7 1.3 1 0 0 1 1 1 0 FAM209 family MIS13 PF08202.11 KFM78632.1 - 0.017 14.4 6.3 0.027 13.8 6.3 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family YabA PF06156.13 KFM78632.1 - 0.022 15.4 0.4 0.022 15.4 0.4 2.9 2 1 1 3 3 2 0 Initiation control protein YabA DivIC PF04977.15 KFM78632.1 - 0.026 14.3 7.0 0.21 11.4 0.3 2.8 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 KFM78632.1 - 0.058 13.8 0.4 0.058 13.8 0.4 2.8 1 1 1 2 2 2 0 Cell division protein ZapB DUF4795 PF16043.5 KFM78632.1 - 0.091 12.4 14.8 0.98 9.0 1.7 2.5 2 1 1 3 3 2 0 Domain of unknown function (DUF4795) CENP-F_leu_zip PF10473.9 KFM78632.1 - 0.096 12.7 16.5 0.17 11.9 14.8 2.1 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 KFM78632.1 - 0.1 12.4 6.8 0.17 11.7 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4164 PF13747.6 KFM78632.1 - 0.14 12.5 3.5 3.4 8.0 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 KFM78632.1 - 0.15 12.1 12.8 0.28 11.2 12.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.12 KFM78632.1 - 0.16 12.3 9.5 0.18 12.2 4.8 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4472 PF14739.6 KFM78632.1 - 0.17 12.6 11.1 0.073 13.8 5.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF948 PF06103.11 KFM78632.1 - 0.18 12.1 1.8 1 9.7 0.3 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 KFM78632.1 - 0.21 11.6 8.2 1.9 8.6 6.5 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 KFM78632.1 - 0.21 12.1 8.9 11 6.7 8.9 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ArsR PF09824.9 KFM78632.1 - 0.27 10.8 4.5 0.25 10.9 2.9 1.7 2 0 0 2 2 2 0 ArsR transcriptional regulator ApoO PF09769.9 KFM78632.1 - 0.3 11.1 3.3 1.1 9.2 2.2 2.4 2 1 0 2 2 2 0 Apolipoprotein O zf-C4H2 PF10146.9 KFM78632.1 - 0.31 11.3 10.3 0.65 10.3 10.3 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4407 PF14362.6 KFM78632.1 - 0.41 10.0 5.5 0.85 8.9 2.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 KFM78632.1 - 0.46 10.8 14.9 0.42 11.0 9.5 3.1 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SOAR PF16533.5 KFM78632.1 - 0.5 10.4 9.0 0.15 12.0 4.0 2.2 1 1 1 2 2 2 0 STIM1 Orai1-activating region CdvA PF18822.1 KFM78632.1 - 0.53 10.1 8.9 4 7.3 2.2 2.8 2 1 1 3 3 3 0 CdvA-like coiled-coil domain DUF4140 PF13600.6 KFM78632.1 - 0.61 10.6 5.3 37 4.8 5.3 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF16 PF01519.16 KFM78632.1 - 0.67 10.5 8.8 0.49 10.9 4.8 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4200 PF13863.6 KFM78632.1 - 0.72 10.3 9.4 2 8.8 9.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Cnn_1N PF07989.11 KFM78632.1 - 0.74 10.0 10.7 8.7 6.6 5.4 3.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 HIP1_clath_bdg PF16515.5 KFM78632.1 - 0.79 10.4 11.8 2.5 8.7 11.6 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3450 PF11932.8 KFM78632.1 - 0.87 8.8 12.0 0.87 8.8 8.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 KFM78632.1 - 1 9.5 13.3 0.29 11.3 8.9 2.0 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KFM78632.1 - 1.1 9.7 8.2 2.6 8.5 0.2 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 KFM78632.1 - 1.3 9.0 9.7 2 8.5 7.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding THOC7 PF05615.13 KFM78632.1 - 1.3 9.3 10.6 67 3.8 10.6 2.3 1 1 0 1 1 1 0 Tho complex subunit 7 BST2 PF16716.5 KFM78632.1 - 1.5 9.5 12.5 1.1 9.9 0.4 2.7 2 1 1 3 3 2 0 Bone marrow stromal antigen 2 Uso1_p115_C PF04871.13 KFM78632.1 - 1.6 9.1 10.6 0.52 10.7 6.9 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BRE1 PF08647.11 KFM78632.1 - 1.6 8.9 11.7 0.037 14.1 4.8 1.9 3 0 0 3 3 1 0 BRE1 E3 ubiquitin ligase bZIP_1 PF00170.21 KFM78632.1 - 1.6 8.9 11.2 4.7 7.4 0.1 2.9 2 1 0 3 3 2 0 bZIP transcription factor DUF713 PF05218.14 KFM78632.1 - 1.7 8.3 11.7 0.23 11.2 2.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF713) HALZ PF02183.18 KFM78632.1 - 2.2 8.5 9.3 17 5.8 0.5 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.6 KFM78632.1 - 2.6 8.2 10.8 0.15 12.2 2.7 2.8 3 0 0 3 3 2 0 Sperm tail C-terminal domain GIT_CC PF16559.5 KFM78632.1 - 2.7 7.9 10.0 0.62 10.0 2.2 3.1 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Vip3A_N PF12495.8 KFM78632.1 - 6.3 6.7 8.1 1.5 8.7 0.8 2.7 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal bZIP_2 PF07716.15 KFM78632.1 - 6.8 6.9 9.7 22 5.3 4.3 2.8 1 1 0 2 2 2 0 Basic region leucine zipper Ion_trans PF00520.31 KFM78635.1 - 1.1e-15 57.5 5.9 1.4e-15 57.2 5.9 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFM78635.1 - 3.7e-11 42.8 3.2 3.7e-11 42.8 3.2 2.0 2 0 0 2 2 2 1 Ion channel DUF2189 PF09955.9 KFM78635.1 - 0.054 13.8 3.0 0.5 10.6 3.0 2.1 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Chordopox_A13L PF05961.11 KFM78635.1 - 0.077 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein MethyTransf_Reg PF10119.9 KFM78635.1 - 0.094 13.4 0.0 0.27 12.0 0.0 1.7 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain PAS_9 PF13426.7 KFM78636.1 - 2.4e-21 75.9 0.0 4.2e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 PAS domain Ion_trans PF00520.31 KFM78636.1 - 1.1e-14 54.2 2.6 1.8e-14 53.6 2.6 1.2 1 0 0 1 1 1 1 Ion transport protein PAS PF00989.25 KFM78636.1 - 2.7e-07 30.6 0.0 5.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KFM78636.1 - 1.7e-05 25.0 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFM78636.1 - 7.2e-05 23.0 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold Vinculin PF01044.19 KFM78638.1 - 0 1261.3 18.3 0 1261.1 18.3 1.0 1 0 0 1 1 1 1 Vinculin family PHA_synth_III_E PF09712.10 KFM78638.1 - 0.0098 15.0 1.1 0.1 11.7 0.2 2.8 2 2 0 2 2 2 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) UPF0193 PF05250.11 KFM78638.1 - 0.019 14.8 2.9 0.045 13.5 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0193) Vps54_N PF10475.9 KFM78638.1 - 0.04 13.2 0.4 0.27 10.5 0.0 2.7 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex ALF PF03752.13 KFM78638.1 - 0.04 13.9 0.2 19 5.3 0.0 3.8 3 0 0 3 3 3 0 Short repeats of unknown function NAS PF03059.16 KFM78638.1 - 0.21 10.9 2.5 43 3.3 0.1 3.8 3 1 1 4 4 4 0 Nicotianamine synthase protein DUF1759 PF03564.15 KFM78638.1 - 0.33 10.9 4.4 3.5 7.5 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1759) Translin PF01997.16 KFM78638.1 - 2 8.4 6.8 37 4.2 0.0 4.1 3 2 0 3 3 3 0 Translin family MutS_III PF05192.18 KFM78638.1 - 3.1 8.0 5.8 1.7e+02 2.3 4.0 3.7 2 1 0 2 2 2 0 MutS domain III Beach PF02138.18 KFM78639.1 - 2.4e-39 135.4 0.0 6e-39 134.1 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PAGK PF15284.6 KFM78639.1 - 0.047 13.6 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 Phage-encoded virulence factor Nipped-B_C PF12830.7 KFM78639.1 - 0.083 12.8 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus WD40 PF00400.32 KFM78641.1 - 5.5e-19 68.2 10.5 9.3e-05 23.1 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM78641.1 - 2.1e-06 27.9 0.0 0.0054 17.0 0.0 4.6 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain RCC1 PF00415.18 KFM78642.1 - 1.3e-59 198.6 17.2 1.2e-14 54.6 0.1 7.0 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM78642.1 - 1.8e-21 75.4 26.1 1.7e-08 34.1 0.1 7.6 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat KRTAP PF11759.8 KFM78642.1 - 6.6 7.4 9.7 6.6 7.4 0.1 3.9 3 2 0 3 3 3 0 Keratin-associated matrix CH PF00307.31 KFM78643.1 - 2.4e-22 79.2 0.0 3.5e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KFM78643.1 - 4.4e-11 42.2 2.9 7.7e-11 41.4 2.9 1.4 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.8 KFM78643.1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain Pkinase PF00069.25 KFM78644.1 - 1.6e-57 194.9 0.0 2.1e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM78644.1 - 7e-35 120.5 0.0 1e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM78644.1 - 1.4e-11 44.3 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFM78644.1 - 0.0013 18.7 0.0 0.46 10.4 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM78644.1 - 0.034 12.9 0.0 0.073 11.8 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase HEXIM PF15313.6 KFM78645.1 - 2.3e-41 141.3 7.6 2.3e-41 141.3 7.6 1.9 2 0 0 2 2 2 1 Hexamethylene bis-acetamide-inducible protein YabA PF06156.13 KFM78645.1 - 0.006 17.2 1.5 0.006 17.2 1.5 3.5 2 1 1 3 3 3 1 Initiation control protein YabA RPW8 PF05659.11 KFM78645.1 - 0.011 15.4 1.8 0.02 14.6 1.1 1.8 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 LAM_C PF12544.8 KFM78645.1 - 0.31 11.2 5.1 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Lysine-2,3-aminomutase PHM7_cyt PF14703.6 KFM78645.1 - 3.5 7.8 12.8 0.28 11.4 5.8 2.0 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter PAS_11 PF14598.6 KFM78647.1 - 9.7e-18 64.4 0.1 9.4e-16 58.0 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFM78647.1 - 1.2e-15 57.5 0.0 1.6e-08 34.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold Period_C PF12114.8 KFM78647.1 - 7.5e-10 38.7 7.3 7.5e-10 38.7 7.3 3.2 2 2 0 2 2 2 1 Period protein 2/3C-terminal region PAS_3 PF08447.12 KFM78647.1 - 1.2e-08 35.2 0.1 6.4e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KFM78647.1 - 0.00052 20.2 0.0 0.35 11.1 0.0 3.1 3 0 0 3 3 3 2 PAS domain Serglycin PF04360.12 KFM78647.1 - 0.13 12.2 10.6 0.29 11.1 7.1 2.5 2 0 0 2 2 2 0 Serglycin RNA_pol PF00940.19 KFM78648.1 - 8.1e-81 272.0 1.8 9.1e-81 271.8 1.8 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase EF-hand_4 PF12763.7 KFM78649.1 - 2.7e-21 75.5 6.2 7.3e-10 38.7 0.0 3.4 4 0 0 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFM78649.1 - 6.2e-14 50.4 4.5 0.00014 21.1 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFM78649.1 - 4.1e-09 35.7 3.6 0.0097 15.8 0.2 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFM78649.1 - 1.4e-07 31.8 0.2 0.011 16.2 0.0 3.4 3 1 0 3 3 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM78649.1 - 4.2e-06 26.0 2.5 0.02 14.4 0.0 3.5 3 0 0 3 3 3 2 EF hand APG6_N PF17675.1 KFM78649.1 - 0.0013 19.2 46.9 0.011 16.2 23.7 2.7 1 1 1 2 2 2 1 Apg6 coiled-coil region EF-hand_8 PF13833.6 KFM78649.1 - 0.0056 16.5 6.0 0.86 9.5 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain pair HrpB7 PF09486.10 KFM78649.1 - 0.0071 16.7 16.7 0.11 12.9 9.0 2.2 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 KFM78649.1 - 0.034 14.4 37.4 1.3 9.2 19.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 KFM78649.1 - 0.053 11.0 34.1 0.21 9.1 34.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 KFM78649.1 - 0.15 10.7 23.0 0.29 9.7 23.0 1.4 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 KFM78649.1 - 0.46 10.9 32.6 0.45 10.9 16.4 2.1 1 1 1 2 2 2 0 Fez1 Macoilin PF09726.9 KFM78649.1 - 1.6 7.2 23.9 2.3 6.7 23.9 1.1 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 KFM78649.1 - 3.3 6.5 40.3 0.39 9.6 31.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 KFM78649.1 - 5 6.4 43.0 2.9 7.2 21.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.8 KFM78649.1 - 7.8 6.1 35.7 0.59 9.7 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) FliJ PF02050.16 KFM78649.1 - 9.4 6.5 33.2 0.34 11.2 15.6 3.0 1 1 3 4 4 4 0 Flagellar FliJ protein EF-hand_4 PF12763.7 KFM78650.1 - 2.2e-10 40.4 0.0 4.6e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFM78650.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain PI31_Prot_N PF11566.8 KFM78651.1 - 6e-07 29.4 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal F-box-like PF12937.7 KFM78651.1 - 2e-05 24.4 0.1 4.7e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM78651.1 - 0.00012 21.8 0.2 0.00025 20.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KFM78651.1 - 0.0074 16.8 0.2 0.013 16.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A IF-2B PF01008.17 KFM78652.1 - 2.3e-77 260.0 0.1 2.6e-77 259.8 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cytochrom_C1 PF02167.15 KFM78653.1 - 6.2e-94 313.8 0.0 7.3e-94 313.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KFM78653.1 - 0.0016 18.7 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KFM78653.1 - 0.002 19.2 0.2 0.0036 18.4 0.2 1.6 1 1 0 1 1 1 1 Cytochrome c Cytochrom_NNT PF03264.14 KFM78653.1 - 0.071 12.8 0.5 0.12 12.1 0.5 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Ig_3 PF13927.6 KFM78654.1 - 2.2e-07 31.4 0.1 4.5e-07 30.4 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM78654.1 - 8.5e-05 22.8 0.1 0.0002 21.6 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM78654.1 - 0.00066 19.7 0.0 0.0019 18.2 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM78654.1 - 0.13 12.4 0.1 0.83 9.9 0.1 2.1 1 1 0 1 1 1 0 Immunoglobulin domain WD40 PF00400.32 KFM78655.1 - 5.4e-09 36.5 2.1 2.5e-05 25.0 0.0 5.2 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM78655.1 - 1.1e-05 25.6 0.0 0.019 15.3 0.0 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KFM78655.1 - 0.0087 15.8 0.0 0.25 11.0 0.0 2.7 2 0 0 2 2 2 1 TUP1-like enhancer of split DUF3288 PF11691.8 KFM78655.1 - 0.031 14.3 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) ANF_receptor PF01094.28 KFM78656.1 - 7.3e-05 22.0 0.0 7.4e-05 22.0 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 KFM78657.1 - 7.6e-07 28.5 0.0 9.2e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Cadherin PF00028.17 KFM78661.1 - 3e-11 43.6 0.9 3.3e-05 24.3 0.1 3.0 2 1 0 2 2 2 2 Cadherin domain Cadherin_2 PF08266.12 KFM78661.1 - 0.015 15.1 0.0 0.44 10.4 0.0 2.5 2 1 1 3 3 3 0 Cadherin-like Cadherin PF00028.17 KFM78662.1 - 3.8e-128 418.3 7.3 1.5e-23 83.0 0.2 7.1 7 0 0 7 7 7 7 Cadherin domain Cadherin_3 PF16184.5 KFM78662.1 - 2.8e-11 43.4 10.8 0.5 10.4 0.1 6.3 6 0 0 6 6 6 5 Cadherin-like Cadherin_2 PF08266.12 KFM78662.1 - 1.6e-10 40.7 0.0 0.33 10.8 0.0 6.2 6 0 0 6 6 6 3 Cadherin-like RET_CLD1 PF17756.1 KFM78662.1 - 3.8e-10 40.1 0.0 1.4 9.2 0.0 6.2 6 0 0 6 6 6 3 RET Cadherin like domain 1 Cadherin_pro PF08758.11 KFM78662.1 - 2.8e-05 24.2 0.0 0.082 13.1 0.0 5.2 6 0 0 6 6 6 1 Cadherin prodomain like PAS_10 PF13596.6 KFM78662.1 - 0.024 15.2 0.0 0.077 13.6 0.0 1.9 1 0 0 1 1 1 0 PAS domain Cadherin PF00028.17 KFM78663.1 - 2e-26 92.3 0.1 7.5e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 Cadherin domain RET_CLD1 PF17756.1 KFM78663.1 - 0.004 17.4 0.0 0.32 11.3 0.0 2.1 2 0 0 2 2 2 2 RET Cadherin like domain 1 Cadherin_2 PF08266.12 KFM78663.1 - 0.0056 16.5 0.0 0.77 9.6 0.0 2.3 2 0 0 2 2 2 2 Cadherin-like Cadherin PF00028.17 KFM78665.1 - 3.8e-99 325.4 12.1 9.3e-23 80.5 0.1 5.1 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 KFM78665.1 - 2.7e-08 33.5 0.2 0.006 16.4 0.0 4.4 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFM78665.1 - 9.6e-08 32.0 11.6 0.017 15.1 0.2 4.9 5 0 0 5 5 5 3 Cadherin-like RET_CLD1 PF17756.1 KFM78665.1 - 0.00025 21.3 0.0 0.86 9.9 0.0 3.5 3 0 0 3 3 3 2 RET Cadherin like domain 1 Cadherin_4 PF17803.1 KFM78665.1 - 0.00087 19.9 17.8 0.34 11.6 0.3 5.3 5 1 0 5 5 5 2 Bacterial cadherin-like domain Glyco_hydro2_C5 PF18565.1 KFM78665.1 - 0.026 14.4 0.4 17 5.3 0.0 3.6 3 0 0 3 3 3 0 Glycoside hydrolase family 2 C-terminal domain 5 PCC_BT PF18140.1 KFM78665.1 - 0.12 12.7 0.2 3.2 8.1 0.0 3.0 3 1 0 3 3 3 0 Propionyl-coenzyme A carboxylase BT domain Big_9 PF17963.1 KFM78665.1 - 3.6 8.4 19.6 1 10.2 1.4 5.0 4 1 1 5 5 5 0 Bacterial Ig domain Cadherin PF00028.17 KFM78666.1 - 3.5e-92 303.0 0.6 1.4e-20 73.6 0.1 6.1 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KFM78666.1 - 2.1e-05 24.2 0.0 0.95 9.3 0.0 4.7 5 0 0 5 5 5 2 Cadherin-like Cadherin_3 PF16184.5 KFM78666.1 - 0.0008 19.4 1.1 1.1 9.3 0.0 4.3 4 0 0 4 4 4 1 Cadherin-like Cadherin_4 PF17803.1 KFM78666.1 - 0.0091 16.6 11.1 0.012 16.3 1.2 4.4 4 0 0 4 4 4 1 Bacterial cadherin-like domain PepSY PF03413.19 KFM78666.1 - 0.033 14.8 0.0 79 3.9 0.0 3.9 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Cadherin PF00028.17 KFM78667.1 - 6.9e-87 286.0 7.6 2.4e-25 88.8 0.1 5.7 6 0 0 6 6 6 5 Cadherin domain Laminin_G_1 PF00054.23 KFM78667.1 - 1.5e-23 83.4 0.0 3.8e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFM78667.1 - 3.5e-20 72.8 1.3 2.8e-19 69.9 0.1 2.7 3 0 0 3 3 3 1 Laminin G domain EGF PF00008.27 KFM78667.1 - 5.7e-20 71.3 62.5 1.3e-06 28.5 7.2 6.6 5 1 0 5 5 5 4 EGF-like domain Cadherin_2 PF08266.12 KFM78667.1 - 4.4e-10 39.3 0.0 0.084 12.7 0.0 4.6 4 1 0 4 4 4 3 Cadherin-like RET_CLD1 PF17756.1 KFM78667.1 - 2.5e-06 27.8 0.0 4 7.8 0.0 4.3 4 0 0 4 4 4 2 RET Cadherin like domain 1 hEGF PF12661.7 KFM78667.1 - 0.00038 21.0 7.8 0.00038 21.0 7.8 7.6 8 0 0 8 8 7 4 Human growth factor-like EGF EGF_2 PF07974.13 KFM78667.1 - 0.0042 17.4 9.9 0.0042 17.4 9.9 6.7 6 1 0 6 6 5 3 EGF-like domain He_PIG PF05345.12 KFM78667.1 - 0.08 13.1 6.6 4 7.7 0.7 4.5 5 0 0 5 5 5 0 Putative Ig domain Y_Y_Y PF07495.13 KFM78667.1 - 0.15 12.0 0.1 25 4.9 0.0 3.1 2 0 0 2 2 2 0 Y_Y_Y domain Laminin_G_3 PF13385.6 KFM78667.1 - 0.41 10.8 2.3 0.51 10.5 0.1 2.4 3 0 0 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily Big_9 PF17963.1 KFM78667.1 - 1.2 9.9 18.8 0.082 13.7 2.8 4.2 5 0 0 5 5 4 0 Bacterial Ig domain Cadherin_4 PF17803.1 KFM78667.1 - 7.8 7.2 19.1 0.22 12.2 1.4 5.2 6 0 0 6 6 6 0 Bacterial cadherin-like domain Laminin_G_2 PF02210.24 KFM78668.1 - 2.4e-10 41.1 0.0 4.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM78668.1 - 6.5e-10 39.3 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain RCR PF12273.8 KFM78668.1 - 0.001 19.7 0.4 0.0031 18.1 0.1 2.0 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF4834 PF16118.5 KFM78668.1 - 0.012 16.6 0.0 0.045 14.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 KFM78668.1 - 0.016 16.0 0.0 0.044 14.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KFM78668.1 - 0.021 14.7 0.1 0.063 13.2 0.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 KFM78668.1 - 0.038 14.0 3.1 0.073 13.1 3.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 KFM78668.1 - 0.073 13.4 0.9 0.29 11.5 0.3 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Cadherin_C PF01049.17 KFM78668.1 - 0.076 13.4 0.4 0.076 13.4 0.4 2.1 2 1 0 2 2 1 0 Cadherin cytoplasmic region DUF5385 PF17359.2 KFM78668.1 - 0.081 12.5 1.3 0.17 11.4 1.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5385) ECSCR PF15820.5 KFM78668.1 - 0.16 11.8 0.1 0.41 10.5 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Man-6-P_recep PF02157.15 KFM78668.1 - 0.23 10.5 0.4 0.41 9.7 0.4 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Syndecan PF01034.20 KFM78668.1 - 0.3 11.0 0.7 0.67 9.9 0.7 1.5 1 0 0 1 1 1 0 Syndecan domain DUF5326 PF17260.2 KFM78668.1 - 0.4 10.9 4.3 0.69 10.1 4.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Baculo_11_kDa PF06143.11 KFM78668.1 - 0.58 9.8 2.1 1.7 8.3 2.1 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family Stevor PF17410.2 KFM78668.1 - 0.77 9.3 3.4 0.44 10.1 0.1 2.0 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Tropomyosin_1 PF12718.7 KFM78671.1 - 0.005 17.0 2.6 0.0068 16.6 2.6 1.1 1 0 0 1 1 1 1 Tropomyosin like PIN_2 PF10130.9 KFM78671.1 - 0.0058 16.9 0.0 0.0076 16.5 0.0 1.3 1 0 0 1 1 1 1 PIN domain FtsX_ECD PF18075.1 KFM78671.1 - 0.012 16.2 1.0 0.017 15.8 1.0 1.2 1 0 0 1 1 1 0 FtsX extracellular domain VPR PF00522.18 KFM78671.1 - 0.05 13.6 0.2 0.079 13.0 0.2 1.3 1 0 0 1 1 1 0 VPR/VPX protein ISK_Channel PF02060.15 KFM78674.1 - 0.00022 20.9 0.1 0.00027 20.6 0.1 1.2 1 0 0 1 1 1 1 Slow voltage-gated potassium channel Ku_PK_bind PF08785.11 KFM78674.1 - 0.013 15.6 0.1 0.016 15.3 0.1 1.2 1 0 0 1 1 1 0 Ku C terminal domain like COX14 PF14880.6 KFM78674.1 - 0.098 12.5 0.6 0.21 11.5 0.6 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly 7tm_1 PF00001.21 KFM78675.1 - 1.6e-10 40.8 0.2 2e-10 40.4 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFM78675.1 - 0.00031 20.1 1.0 0.00039 19.8 1.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw LSR PF05624.14 KFM78675.1 - 2.1 8.4 9.0 2.6 8.1 2.7 2.2 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Prominin PF05478.11 KFM78677.1 - 5.7e-22 77.5 3.4 7.2e-22 77.2 3.4 1.0 1 0 0 1 1 1 1 Prominin TRP PF06011.12 KFM78677.1 - 0.00015 20.6 2.5 0.00017 20.4 2.5 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Ni_hydr_CYTB PF01292.20 KFM78677.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF2207 PF09972.9 KFM78677.1 - 0.0099 14.7 0.1 0.011 14.6 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4405 PF14358.6 KFM78677.1 - 0.014 15.9 0.7 0.014 15.9 0.7 2.2 2 1 0 2 2 1 0 Domain of unknown function (DUF4405) DUF898 PF05987.13 KFM78677.1 - 0.052 12.6 0.4 0.19 10.7 0.2 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) SUR7 PF06687.12 KFM78677.1 - 0.056 13.1 4.3 0.028 14.0 1.5 1.7 2 0 0 2 2 2 0 SUR7/PalI family SdpI PF13630.6 KFM78677.1 - 0.13 12.5 0.0 0.13 12.5 0.0 2.5 3 0 0 3 3 2 0 SdpI/YhfL protein family CrgA PF06781.12 KFM78677.1 - 0.94 9.6 4.7 14 5.8 2.2 2.4 1 1 1 2 2 2 0 Cell division protein CrgA EphA2_TM PF14575.6 KFM78677.1 - 1.1 10.2 6.9 1.5e+02 3.3 4.6 3.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4083 PF13314.6 KFM78677.1 - 3.2 7.8 5.5 0.89 9.5 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4083) DUF4834 PF16118.5 KFM78677.1 - 4.7 8.3 8.3 1 10.4 0.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) Prominin PF05478.11 KFM78678.1 - 8.1e-56 189.5 11.2 5.8e-55 186.7 11.2 1.9 1 1 0 1 1 1 1 Prominin Apolipoprotein PF01442.18 KFM78678.1 - 0.00017 21.6 1.0 0.0059 16.5 0.2 2.2 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain FlaC_arch PF05377.11 KFM78678.1 - 0.0015 18.9 0.9 0.0015 18.9 0.9 2.7 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 KFM78678.1 - 0.0015 18.6 4.1 0.0059 16.7 3.7 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 KFM78678.1 - 0.0022 16.8 9.8 0.0028 16.4 9.8 1.0 1 0 0 1 1 1 1 AAA domain Bacillus_HBL PF05791.11 KFM78678.1 - 0.0024 17.7 4.0 0.26 11.1 0.3 2.7 1 1 1 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) DUF2096 PF09869.9 KFM78678.1 - 0.016 15.3 3.2 1 9.4 0.4 2.9 1 1 3 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2096) V-SNARE PF05008.15 KFM78678.1 - 0.019 15.3 3.7 0.041 14.3 0.2 2.8 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus ApoLp-III PF07464.11 KFM78678.1 - 0.02 15.0 6.0 0.045 13.8 3.7 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Laminin_II PF06009.12 KFM78678.1 - 0.027 14.5 0.2 0.027 14.5 0.2 2.2 1 1 1 2 2 2 0 Laminin Domain II Amastin PF07344.11 KFM78678.1 - 0.033 14.0 4.1 0.07 13.0 4.1 1.6 1 0 0 1 1 1 0 Amastin surface glycoprotein K-box PF01486.17 KFM78678.1 - 0.038 14.2 2.5 0.05 13.8 0.8 1.9 2 0 0 2 2 2 0 K-box region Nsp1_C PF05064.13 KFM78678.1 - 0.052 13.3 1.0 0.22 11.3 0.1 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region Flt3_lig PF02947.14 KFM78678.1 - 0.068 13.4 0.3 0.37 11.0 0.1 2.1 1 1 1 2 2 2 0 flt3 ligand APG6_N PF17675.1 KFM78678.1 - 0.069 13.7 8.0 0.12 12.9 8.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 KFM78678.1 - 0.075 13.1 2.8 0.84 9.7 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 KFM78678.1 - 0.079 13.2 0.3 0.079 13.2 0.3 2.9 3 0 0 3 3 2 0 Haemolysin XhlA COG2 PF06148.11 KFM78678.1 - 0.083 13.0 5.3 5.7 7.0 0.2 3.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Snapin_Pallidin PF14712.6 KFM78678.1 - 0.09 13.2 0.1 0.09 13.2 0.1 2.6 2 1 1 3 3 2 0 Snapin/Pallidin GLE1 PF07817.13 KFM78678.1 - 0.16 11.1 2.0 0.21 10.8 1.3 1.5 1 1 0 1 1 1 0 GLE1-like protein CENP-F_leu_zip PF10473.9 KFM78678.1 - 0.2 11.7 9.4 0.45 10.5 0.4 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DNA_repr_REX1B PF14966.6 KFM78678.1 - 0.38 11.4 1.8 8.7 7.1 0.2 2.6 1 1 1 2 2 2 0 DNA repair REX1-B DUF5082 PF16888.5 KFM78678.1 - 0.41 10.9 4.7 4.1 7.7 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF1218 PF06749.12 KFM78678.1 - 0.54 10.8 3.3 1.3 9.6 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) Seryl_tRNA_N PF02403.22 KFM78678.1 - 0.58 10.4 9.0 0.15 12.3 0.9 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ING PF12998.7 KFM78678.1 - 0.73 10.5 5.2 31 5.2 0.1 3.0 1 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding CorA PF01544.18 KFM78678.1 - 0.77 9.0 8.0 0.59 9.4 1.0 2.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein NPV_P10 PF05531.12 KFM78678.1 - 0.83 10.2 5.0 2.6 8.6 0.2 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Claudin_2 PF13903.6 KFM78678.1 - 1.2 8.8 6.2 2.2 8.0 6.2 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4404 PF14357.6 KFM78678.1 - 1.8 9.2 6.4 11 6.8 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) TMPIT PF07851.13 KFM78678.1 - 2.1 7.5 4.5 5.8 6.1 0.1 2.4 1 1 1 2 2 2 0 TMPIT-like protein BLOC1_2 PF10046.9 KFM78678.1 - 2.1 8.7 7.7 0.3 11.4 1.1 2.6 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Muted PF14942.6 KFM78678.1 - 2.4 8.5 9.1 2.1 8.7 2.3 2.4 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Occludin_ELL PF07303.13 KFM78678.1 - 2.4 8.9 6.4 5.3 7.8 0.4 2.5 3 0 0 3 3 2 0 Occludin homology domain Fib_alpha PF08702.10 KFM78678.1 - 2.6 8.2 5.8 0.88 9.8 2.6 1.9 2 1 0 2 2 1 0 Fibrinogen alpha/beta chain family Sec34 PF04136.15 KFM78678.1 - 4.4 7.2 8.7 2.8 7.8 0.6 3.1 2 1 2 4 4 4 0 Sec34-like family ArAE_1_C PF11728.8 KFM78678.1 - 5 7.1 9.1 5.9 6.9 1.8 3.1 3 1 1 4 4 4 0 Putative aromatic acid exporter C-terminal domain Ig_3 PF13927.6 KFM78680.1 - 3.6e-30 104.4 0.1 5.2e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM78680.1 - 1.5e-28 98.7 0.2 2.9e-13 49.7 0.1 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM78680.1 - 1.6e-16 60.2 0.2 1e-07 32.0 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM78680.1 - 7.7e-15 55.0 1.5 4.9e-06 26.8 0.6 3.0 1 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM78680.1 - 3.7e-11 43.2 0.6 3e-05 24.1 0.1 3.2 2 1 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM78680.1 - 1.2e-09 38.1 0.9 0.00035 20.6 0.1 3.0 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFM78680.1 - 0.0042 17.1 0.0 0.67 10.0 0.0 3.3 3 1 0 3 3 3 1 C17orf99 Ig domain Peptidase_A17 PF05380.13 KFM78681.1 - 1.8e-06 28.1 0.0 2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Pao retrotransposon peptidase ECSCR PF15820.5 KFM78683.1 - 9.8 6.1 7.7 14 5.6 0.4 3.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Shisa PF13908.6 KFM78684.1 - 0.03 14.6 0.4 0.03 14.6 0.4 2.3 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF3487 PF11990.8 KFM78684.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) EGF_MSP1_1 PF12946.7 KFM78685.1 - 4.5e-26 90.6 243.6 0.00033 20.6 10.5 17.7 3 3 14 17 17 17 15 MSP1 EGF domain 1 EGF PF00008.27 KFM78685.1 - 2e-09 37.6 34.8 8.2e-06 26.0 5.7 21.1 17 2 2 19 19 19 3 EGF-like domain EGF_2 PF07974.13 KFM78685.1 - 0.0033 17.8 14.7 0.0033 17.8 14.7 26.7 6 3 12 18 18 18 3 EGF-like domain SLAC1 PF03595.17 KFM78685.1 - 0.071 12.4 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel EGF_CA PF07645.15 KFM78686.1 - 4.5e-10 39.6 10.0 4.5e-10 39.6 10.0 3.5 3 0 0 3 3 3 2 Calcium-binding EGF domain cEGF PF12662.7 KFM78686.1 - 3.4e-05 23.7 18.4 0.0001 22.2 0.5 3.4 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF PF00008.27 KFM78686.1 - 8.6e-05 22.8 31.9 0.05 13.9 8.6 3.5 3 0 0 3 3 3 3 EGF-like domain EGF_MSP1_1 PF12946.7 KFM78686.1 - 0.00019 21.4 5.4 0.00019 21.4 5.4 2.7 2 0 0 2 2 2 1 MSP1 EGF domain 1 hEGF PF12661.7 KFM78686.1 - 0.0045 17.6 23.5 0.06 14.0 5.0 3.8 3 0 0 3 3 3 3 Human growth factor-like EGF FXa_inhibition PF14670.6 KFM78686.1 - 0.0071 16.6 27.2 0.0075 16.5 4.8 3.8 2 1 1 3 3 3 1 Coagulation Factor Xa inhibitory site PTP_tm PF18861.1 KFM78686.1 - 0.016 15.2 0.4 0.035 14.1 0.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EGF_3 PF12947.7 KFM78686.1 - 0.024 14.8 33.1 0.16 12.2 7.9 3.5 3 0 0 3 3 3 0 EGF domain Glycophorin_A PF01102.18 KFM78686.1 - 0.055 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A DUF2627 PF11118.8 KFM78686.1 - 0.16 12.5 0.1 0.27 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Plasmod_Pvs28 PF06247.11 KFM78686.1 - 0.63 10.4 28.9 0.53 10.6 1.0 3.4 3 0 0 3 3 3 0 Pvs28 EGF domain RVT_1 PF00078.27 KFM78687.1 - 5.1e-06 26.2 0.2 5.3e-06 26.1 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) STAT2_C PF12188.8 KFM78687.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal PDGF PF00341.17 KFM78688.1 - 2.4e-14 53.4 4.6 2.4e-14 53.4 4.6 2.5 2 1 0 2 2 2 1 PDGF/VEGF domain MFS_1_like PF12832.7 KFM78689.1 - 1.7e-70 237.8 20.9 2.1e-70 237.5 20.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM78689.1 - 1.7e-17 63.4 35.5 7e-07 28.5 21.5 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 KFM78689.1 - 2.9e-09 36.2 23.7 8.2e-06 24.8 1.1 3.1 3 0 0 3 3 3 2 LacY proton/sugar symporter Nuc_H_symport PF03825.16 KFM78689.1 - 0.15 11.0 28.6 1.1 8.2 0.2 2.8 2 1 0 2 2 2 0 Nucleoside H+ symporter W2 PF02020.18 KFM78690.1 - 4.3e-07 30.0 2.1 0.00097 19.2 0.3 2.3 2 1 0 2 2 2 2 eIF4-gamma/eIF5/eIF2-epsilon Thioredoxin_2 PF13098.6 KFM78690.1 - 2e-05 25.0 0.4 0.00016 22.1 0.4 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 KFM78690.1 - 2.3e-05 24.3 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 KFM78690.1 - 4.6e-05 23.4 0.0 0.00013 21.9 0.0 1.8 2 1 0 2 2 2 1 Thioredoxin domain TraF PF13728.6 KFM78690.1 - 0.00031 20.7 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KFM78690.1 - 0.00078 19.7 0.0 0.0055 17.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KFM78690.1 - 0.0068 16.3 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family DUF393 PF04134.12 KFM78690.1 - 0.033 15.5 0.3 0.1 14.0 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF393 zf-TFIIB PF13453.6 KFM78690.1 - 0.059 12.7 0.5 0.13 11.6 0.1 1.8 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF2847 PF11009.8 KFM78690.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DUF5490 PF17593.2 KFM78690.1 - 0.31 11.1 1.9 7.1 6.7 0.0 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5490) Thioredoxin PF00085.20 KFM78691.1 - 2e-33 114.4 1.0 2.7e-05 24.1 0.1 6.3 6 0 0 6 6 6 6 Thioredoxin Thioredoxin_2 PF13098.6 KFM78691.1 - 1.9e-21 76.6 15.2 0.0032 17.9 0.0 8.4 5 4 1 6 6 6 5 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KFM78691.1 - 5.8e-17 61.5 0.0 0.0032 17.5 0.0 6.6 6 0 0 6 6 6 3 Thioredoxin domain HyaE PF07449.11 KFM78691.1 - 3.3e-15 56.0 3.4 0.61 10.1 0.0 6.5 6 0 0 6 6 6 6 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 KFM78691.1 - 3.5e-14 52.8 3.7 0.002 18.0 0.0 5.8 5 1 0 5 5 5 3 AhpC/TSA family Thioredoxin_8 PF13905.6 KFM78691.1 - 1.9e-11 44.1 3.8 0.074 13.4 0.0 7.0 6 1 0 6 6 6 2 Thioredoxin-like TraF PF13728.6 KFM78691.1 - 4.5e-11 43.0 0.2 0.087 12.6 0.0 6.2 6 0 0 6 6 6 3 F plasmid transfer operon protein DUF836 PF05768.14 KFM78691.1 - 4.1e-08 33.5 1.9 0.1 13.0 0.0 5.5 5 0 0 5 5 5 1 Glutaredoxin-like domain (DUF836) Thioredoxin_5 PF13743.6 KFM78691.1 - 6.4e-07 29.2 1.5 1.5 8.5 0.0 5.2 5 0 0 5 5 5 2 Thioredoxin Redoxin PF08534.10 KFM78691.1 - 1.3e-06 28.1 0.0 0.13 12.0 0.0 3.7 4 0 0 4 4 3 2 Redoxin KaiB PF07689.12 KFM78691.1 - 0.0001 22.0 0.0 0.14 11.9 0.0 4.2 4 0 0 4 4 4 1 KaiB domain Glutaredoxin PF00462.24 KFM78691.1 - 0.00012 22.2 1.0 9.2 6.6 0.1 4.8 4 0 0 4 4 4 0 Glutaredoxin W2 PF02020.18 KFM78691.1 - 0.025 14.7 21.2 0.1 12.7 0.3 5.7 6 0 0 6 6 5 0 eIF4-gamma/eIF5/eIF2-epsilon Glyco_tran_WbsX PF14307.6 KFM78691.1 - 0.074 12.5 1.5 6.6 6.1 0.0 3.2 3 0 0 3 3 3 0 Glycosyltransferase WbsX Cass2 PF14526.6 KFM78691.1 - 0.11 12.6 2.5 0.48 10.6 0.0 3.0 3 1 0 3 3 3 0 Integron-associated effector binding protein DUF2757 PF10955.8 KFM78691.1 - 0.17 12.2 10.1 39 4.6 0.1 5.5 6 0 0 6 6 4 0 Protein of unknown function (DUF2757) DUF4110 PF13422.6 KFM78691.1 - 0.25 11.4 1.3 15 5.7 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4110) Metalloenzyme PF01676.18 KFM78691.1 - 0.31 10.4 0.8 27 4.0 0.0 3.6 1 1 1 2 2 2 0 Metalloenzyme superfamily C1_1 PF00130.22 KFM78691.1 - 0.73 9.8 8.5 2.4 8.1 0.6 3.9 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3979 PF13141.6 KFM78691.1 - 1 9.6 11.0 0.23 11.7 1.3 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF3979) DAPDH_C PF16654.5 KFM78691.1 - 1.5 8.6 4.1 4.2 7.2 0.1 2.8 3 0 0 3 3 3 0 Diaminopimelic acid dehydrogenase C-terminal domain SpoU_sub_bind PF08032.12 KFM78691.1 - 3.9 7.8 6.3 75 3.7 0.1 4.8 6 0 0 6 6 5 0 RNA 2'-O ribose methyltransferase substrate binding DUF1456 PF07308.13 KFM78691.1 - 4.1 7.8 11.5 11 6.4 0.1 5.4 5 1 1 6 6 6 0 Protein of unknown function (DUF1456) Thioredoxin_6 PF13848.6 KFM78692.1 - 5.6e-14 52.5 5.5 7.9e-08 32.4 2.0 3.2 1 1 2 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KFM78692.1 - 2e-10 41.1 0.6 0.012 16.1 0.1 4.0 2 2 1 3 3 3 2 Thioredoxin-like domain HyaE PF07449.11 KFM78692.1 - 1.7e-05 24.7 0.0 0.23 11.5 0.0 3.1 3 2 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KFM78692.1 - 4.3e-05 23.8 0.3 0.52 10.7 0.1 4.0 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin PF00085.20 KFM78692.1 - 8.5e-05 22.5 0.1 0.027 14.4 0.1 2.9 3 0 0 3 3 3 1 Thioredoxin HSDR_N PF04313.14 KFM78692.1 - 0.0037 17.2 0.4 0.02 14.9 0.2 2.2 2 1 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) NIF PF03031.18 KFM78692.1 - 0.0046 16.7 1.2 0.011 15.5 0.2 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase TMP-TENI PF02581.17 KFM78692.1 - 0.048 13.0 1.2 2.8 7.2 0.1 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase FliG_M PF14841.6 KFM78692.1 - 0.074 13.3 0.2 0.5 10.6 0.0 2.4 2 1 0 2 2 2 0 FliG middle domain Thioredoxin PF00085.20 KFM78693.1 - 1.5e-07 31.3 0.1 2.1e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KFM78693.1 - 4.2e-05 23.5 0.0 9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KFM78693.1 - 7.3e-05 23.2 0.3 0.0045 17.4 0.3 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KFM78693.1 - 0.002 18.1 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.6 KFM78693.1 - 0.0058 16.5 0.1 0.014 15.2 0.1 1.5 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KFM78693.1 - 0.025 14.9 0.0 0.34 11.3 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 KFM78693.1 - 0.1 12.5 0.1 0.38 10.7 0.1 1.8 1 1 1 2 2 2 0 AhpC/TSA family LRR_8 PF13855.6 KFM78694.1 - 1.2e-21 76.2 20.3 6.4e-10 38.7 2.3 4.0 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KFM78694.1 - 4.4e-09 36.5 30.1 0.0034 17.7 4.1 5.8 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM78694.1 - 0.00022 21.3 22.1 2 9.3 0.2 7.6 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 KFM78694.1 - 0.0018 17.8 10.1 0.14 11.7 1.4 3.1 1 1 3 4 4 4 2 Leucine-rich repeat LRR_5 PF13306.6 KFM78694.1 - 0.0071 16.3 9.2 0.0084 16.1 0.7 2.9 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Pacs-1 PF10254.9 KFM78696.1 - 3.6e-155 517.0 2.0 3.6e-155 517.0 2.0 1.9 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein Ste5_C PF12194.8 KFM78696.1 - 0.0041 17.1 0.1 0.014 15.4 0.1 1.9 1 0 0 1 1 1 1 Protein kinase Fus3-binding PDZ_6 PF17820.1 KFM78697.1 - 0.011 15.6 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 PDZ domain PAP2 PF01569.21 KFM78698.1 - 3.4e-14 52.8 1.2 4.2e-14 52.5 1.2 1.1 1 0 0 1 1 1 1 PAP2 superfamily MNHE PF01899.16 KFM78698.1 - 0.0048 16.7 0.1 0.0058 16.4 0.1 1.1 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit Peptidase_U4 PF03419.13 KFM78698.1 - 0.054 12.8 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA CH PF00307.31 KFM78701.1 - 6.2e-36 122.9 1.3 4.8e-22 78.2 0.6 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM78701.1 - 1.1e-09 38.0 0.1 4e-05 23.4 0.0 2.5 2 1 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.21 KFM78702.1 - 2.7e-16 59.9 14.4 3e-13 50.2 5.5 2.1 2 0 0 2 2 2 2 Spectrin repeat DUF668 PF05003.12 KFM78702.1 - 0.071 13.6 0.9 2.6 8.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF668) DUF1870 PF08965.10 KFM78702.1 - 0.13 12.3 2.1 4.8 7.2 0.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1870) Hemerythrin PF01814.23 KFM78702.1 - 0.18 12.4 4.8 0.59 10.8 4.9 1.7 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain MutS_IV PF05190.18 KFM78702.1 - 0.2 12.0 3.8 0.62 10.5 0.2 2.6 1 1 0 2 2 2 0 MutS family domain IV Cob_adeno_trans PF01923.18 KFM78702.1 - 0.38 10.9 4.0 1.6 8.8 1.1 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase ARA70 PF12489.8 KFM78702.1 - 0.45 10.7 10.5 3.4 7.8 10.4 2.1 1 1 0 1 1 1 0 Nuclear coactivator Myb_CC_LHEQLE PF14379.6 KFM78702.1 - 0.52 10.1 9.9 0.4 10.4 0.8 3.4 3 0 0 3 3 3 0 MYB-CC type transfactor, LHEQLE motif Syntaxin-6_N PF09177.11 KFM78702.1 - 0.69 10.5 6.7 0.14 12.7 1.4 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 KFM78702.1 - 2.1 7.8 5.5 2.6 7.5 5.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran_CTD PF16326.5 KFM78702.1 - 2.9 8.2 13.2 2.1 8.6 1.5 2.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain Spectrin PF00435.21 KFM78703.1 - 2.2e-52 175.9 166.2 2.5e-11 44.0 5.5 16.3 16 2 1 17 17 17 13 Spectrin repeat Rotamase PF00639.21 KFM78703.1 - 4.8 8.2 8.1 8.9 7.4 0.3 5.7 2 2 1 3 3 3 0 PPIC-type PPIASE domain Pkinase_Tyr PF07714.17 KFM78704.1 - 3.3e-86 288.8 0.0 5e-86 288.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.28 KFM78704.1 - 1e-44 153.1 1.3 1e-44 153.1 0.3 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region Pkinase PF00069.25 KFM78704.1 - 8.5e-41 140.1 0.0 1.4e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KFM78704.1 - 0.039 12.9 0.1 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain zf-C2H2 PF00096.26 KFM78706.1 - 3.1e-30 102.9 98.5 0.00011 22.5 0.1 13.0 13 1 0 13 13 12 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78706.1 - 1.5e-27 93.9 90.0 0.0046 17.7 0.2 13.3 14 0 0 14 14 14 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM78706.1 - 4.9e-13 48.7 66.2 0.0014 18.6 2.0 10.8 9 1 1 10 10 10 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM78706.1 - 5.9e-11 42.3 79.0 0.019 15.4 0.2 15.0 14 1 0 14 14 14 8 Zinc-finger double domain zf-met PF12874.7 KFM78706.1 - 5.6e-08 32.9 74.3 0.16 12.4 0.8 11.4 12 0 0 12 12 12 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM78706.1 - 3.8e-07 30.2 74.7 0.063 13.6 1.2 12.2 11 1 1 12 12 12 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM78706.1 - 0.0046 16.7 1.8 0.0046 16.7 1.8 8.2 10 1 0 10 10 9 1 C2H2-type zinc-finger domain BHD_1 PF10403.9 KFM78706.1 - 0.11 12.4 0.3 26 4.7 0.0 3.0 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 Zf_RING PF16744.5 KFM78706.1 - 0.13 12.4 0.1 0.13 12.4 0.1 8.5 8 3 1 9 9 8 0 KIAA1045 RING finger Synaptobrevin PF00957.21 KFM78706.1 - 0.26 11.1 1.1 0.55 10.1 1.1 1.5 1 0 0 1 1 1 0 Synaptobrevin GAGA PF09237.11 KFM78706.1 - 0.47 10.3 0.0 0.47 10.3 0.0 3.5 4 0 0 4 4 4 0 GAGA factor zf-Di19 PF05605.12 KFM78706.1 - 2 8.7 56.8 0.051 13.9 2.1 8.0 8 0 0 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding Baculo_IE-1 PF05290.11 KFM78706.1 - 3.6 7.5 27.6 0.21 11.5 7.8 5.2 4 2 1 5 5 5 0 Baculovirus immediate-early protein (IE-0) ADK_lid PF05191.14 KFM78706.1 - 5.1 7.2 36.5 4.1 7.5 0.1 8.0 6 2 1 7 7 7 0 Adenylate kinase, active site lid ADH_N PF08240.12 KFM78707.1 - 1.2e-26 92.7 2.7 1.2e-26 92.7 2.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM78707.1 - 1.1e-18 67.4 0.0 1.6e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFM78707.1 - 1.8e-12 47.2 0.4 1.3e-11 44.4 0.4 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFM78707.1 - 0.0021 19.1 0.0 0.0044 18.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM78709.1 - 2.2e-19 69.3 3.2 3.5e-19 68.7 3.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM78709.1 - 6.3e-10 39.1 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFM78709.1 - 3.6e-06 26.6 0.0 5.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus TSP_1 PF00090.19 KFM78710.1 - 2.5e-35 120.4 145.6 8.2e-07 29.2 3.1 13.3 13 0 0 13 13 13 10 Thrombospondin type 1 domain I-set PF07679.16 KFM78710.1 - 1.1e-09 38.2 0.0 3.2e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM78710.1 - 3e-08 34.2 0.1 5.4e-07 30.1 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 KFM78710.1 - 3.9e-07 30.3 0.0 3.9e-07 30.3 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain PLAC PF08686.11 KFM78710.1 - 4.1e-05 24.2 14.6 7.1e-05 23.5 12.0 3.0 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain ig PF00047.25 KFM78710.1 - 0.00027 21.0 0.0 0.00099 19.2 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM78710.1 - 0.00056 20.1 0.1 0.0079 16.4 0.1 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Siah-Interact_N PF09032.11 KFM78711.1 - 0.0099 16.2 0.5 0.01 16.1 0.5 1.2 1 0 0 1 1 1 1 Siah interacting protein, N terminal BAR PF03114.18 KFM78712.1 - 0.00012 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 BAR domain BAR PF03114.18 KFM78713.1 - 7.9e-09 35.5 1.5 8.7e-09 35.4 1.5 1.0 1 0 0 1 1 1 1 BAR domain DUF3150 PF11348.8 KFM78713.1 - 0.056 12.7 0.8 0.06 12.6 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Herpes_ICP4_N PF03584.15 KFM78713.1 - 0.095 12.5 0.1 0.16 11.8 0.1 1.3 1 1 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Com_YlbF PF06133.11 KFM78713.1 - 0.33 11.6 3.8 0.41 11.3 3.4 1.4 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA RhoGEF PF00621.20 KFM78714.1 - 2.2e-18 67.2 0.1 2.4e-18 67.0 0.1 1.0 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 KFM78715.1 - 2e-29 101.2 0.1 1.7e-09 37.4 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFM78715.1 - 1.2e-28 98.5 0.1 2e-09 36.9 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KFM78715.1 - 3.5e-24 84.3 2.4 3.9e-07 29.6 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 KFM78715.1 - 0.0026 18.0 2.2 1.5 9.2 0.0 3.2 3 0 0 3 3 3 2 Bacterial SH3 domain LPP PF04728.13 KFM78715.1 - 0.11 12.9 0.2 0.11 12.9 0.2 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF1192 PF06698.11 KFM78715.1 - 0.28 11.3 0.1 0.28 11.3 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Golgin_A5 PF09787.9 KFM78715.1 - 0.79 9.1 16.4 1.4 8.3 16.4 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 FlxA PF14282.6 KFM78715.1 - 1.8 8.6 16.1 7.8 6.6 16.1 2.1 1 1 0 1 1 1 0 FlxA-like protein DUF2120 PF09893.9 KFM78715.1 - 2.4 8.2 7.2 1.1 9.4 3.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF812 PF05667.11 KFM78715.1 - 3 6.6 20.7 5.7 5.7 20.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Ribosomal_S3_C PF00189.20 KFM78717.1 - 8.6e-23 80.7 0.5 3.8e-22 78.6 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KFM78717.1 - 9.9e-11 41.3 0.1 1.6e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 KFM78717.1 - 0.21 11.4 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus Ephrin_rec_like PF07699.13 KFM78718.1 - 1.9e-72 238.8 104.0 4.8e-12 45.4 4.0 10.4 9 1 1 10 10 9 7 Putative ephrin-receptor like EGF PF00008.27 KFM78718.1 - 6.3e-72 237.4 268.2 8.8e-09 35.5 4.9 23.3 22 0 0 22 22 22 16 EGF-like domain CUB PF00431.20 KFM78718.1 - 1.6e-50 170.1 0.0 1.3e-18 67.4 0.0 3.7 3 0 0 3 3 3 3 CUB domain Sushi PF00084.20 KFM78718.1 - 1.7e-43 147.0 64.1 2.2e-10 40.9 0.1 12.7 12 0 0 12 12 10 8 Sushi repeat (SCR repeat) hEGF PF12661.7 KFM78718.1 - 3.6e-40 135.3 215.4 1.7e-06 28.4 4.6 22.3 22 0 0 22 22 20 12 Human growth factor-like EGF HYR PF02494.16 KFM78718.1 - 2.1e-29 101.6 8.1 4.4e-12 46.2 0.0 4.2 4 0 0 4 4 4 3 HYR domain F5_F8_type_C PF00754.25 KFM78718.1 - 1.5e-20 73.6 0.0 2.4e-10 40.6 0.0 2.6 2 0 0 2 2 2 2 F5/8 type C domain EGF_CA PF07645.15 KFM78718.1 - 1.8e-11 44.1 25.2 4.9e-08 33.0 9.7 24.9 13 5 11 24 24 20 10 Calcium-binding EGF domain Laminin_G_3 PF13385.6 KFM78718.1 - 2.4e-10 40.8 0.3 5.3e-10 39.6 0.3 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Ldl_recept_a PF00057.18 KFM78718.1 - 1.8e-09 37.7 14.1 1.8e-09 37.7 14.1 8.4 9 1 1 10 10 3 1 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 KFM78718.1 - 4.2e-06 26.9 8.0 4.2e-06 26.9 8.0 24.3 17 6 8 25 25 20 3 Coagulation Factor Xa inhibitory site Laminin_G_2 PF02210.24 KFM78718.1 - 0.0017 18.9 0.0 0.0035 17.9 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain EGF_2 PF07974.13 KFM78718.1 - 0.0029 17.9 10.0 0.0029 17.9 10.0 21.3 21 0 0 21 21 19 10 EGF-like domain Nup160 PF11715.8 KFM78722.1 - 2.1e-53 181.8 0.2 2.5e-53 181.6 0.2 1.0 1 0 0 1 1 1 1 Nucleoporin Nup120/160 zf-C4 PF00105.18 KFM78724.1 - 6.7e-29 100.2 11.5 7.7e-29 100.0 11.5 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 KFM78724.1 - 0.053 13.8 0.6 0.053 13.8 0.6 2.3 2 0 0 2 2 2 0 C1 domain DNA_pol_B_2 PF03175.13 KFM78725.1 - 4.6e-16 58.7 0.0 6.5e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_F12L PF03337.13 KFM78725.1 - 0.0073 14.5 0.4 0.12 10.5 0.1 2.0 1 1 1 2 2 2 2 Poxvirus F12L protein MULE PF10551.9 KFM78727.1 - 2.1e-10 40.9 0.0 3e-09 37.2 0.0 2.5 2 0 0 2 2 2 1 MULE transposase domain EGF_2 PF07974.13 KFM78727.1 - 0.039 14.3 0.7 0.11 12.8 0.7 1.8 1 0 0 1 1 1 0 EGF-like domain Crystall_4 PF17945.1 KFM78729.1 - 0.052 14.0 0.0 0.052 14.0 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin Laminin_EGF PF00053.24 KFM78730.1 - 1e-29 102.4 206.3 0.0061 16.7 15.7 12.0 1 1 10 11 11 11 10 Laminin EGF domain EGF PF00008.27 KFM78730.1 - 1.1e-08 35.2 211.8 0.0057 16.9 11.1 14.6 14 1 0 14 14 14 9 EGF-like domain hEGF PF12661.7 KFM78730.1 - 6.9e-08 32.8 171.2 0.00095 19.7 4.9 16.4 12 3 3 15 15 15 9 Human growth factor-like EGF EGF_2 PF07974.13 KFM78730.1 - 0.004 17.5 243.1 0.023 15.0 11.9 17.8 12 9 2 14 14 14 8 EGF-like domain Laminin_EGF PF00053.24 KFM78731.1 - 1.5e-42 143.5 341.9 0.0046 17.1 10.0 19.3 2 1 16 18 18 18 18 Laminin EGF domain hEGF PF12661.7 KFM78731.1 - 3.4e-15 56.0 297.4 0.00034 21.1 5.6 24.7 20 6 6 26 26 26 17 Human growth factor-like EGF EGF_2 PF07974.13 KFM78731.1 - 4.1e-06 27.0 426.3 0.00053 20.3 9.7 26.6 20 9 1 21 21 21 12 EGF-like domain EGF PF00008.27 KFM78731.1 - 2.3 8.6 346.7 0.044 14.1 11.1 22.1 21 4 0 21 21 21 0 EGF-like domain Tlr3_TMD PF17968.1 KFM78732.1 - 2.7 8.3 7.6 17 5.7 7.6 2.1 1 1 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain Pkinase PF00069.25 KFM78735.1 - 1.6e-66 224.4 0.0 2.7e-66 223.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM78735.1 - 7.7e-42 143.4 0.0 1.4e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM78735.1 - 0.002 17.5 0.0 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFM78735.1 - 0.0041 16.8 0.2 0.24 11.0 0.0 2.4 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFM78735.1 - 0.0079 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KFM78735.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 KFM78735.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KFM78735.1 - 0.043 12.6 0.4 0.084 11.6 0.4 1.6 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KFM78735.1 - 0.064 12.9 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 RIO1 family RHIM PF12721.7 KFM78737.1 - 0.096 13.2 0.2 0.13 12.8 0.2 1.2 1 0 0 1 1 1 0 RIP homotypic interaction motif Tnp_P_element_C PF12596.8 KFM78738.1 - 0.011 16.2 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 0 87kDa Transposase Transglut_C PF00927.22 KFM78740.1 - 3.5e-33 113.9 0.1 1.1e-15 57.7 0.2 2.3 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 KFM78740.1 - 2.8e-27 95.4 0.0 8.2e-26 90.7 0.0 2.6 2 0 0 2 2 2 1 Transglutaminase family Transglut_core PF01841.19 KFM78740.1 - 1.2e-16 61.1 1.5 1.3e-16 61.0 0.2 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF1616 PF07760.11 KFM78740.1 - 0.00095 18.6 0.1 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) fn3_5 PF06280.12 KFM78740.1 - 0.0084 16.8 0.2 0.026 15.2 0.2 2.0 1 0 0 1 1 1 1 Fn3-like domain DUF1896 PF08989.10 KFM78740.1 - 0.012 15.7 0.8 0.022 14.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) DUF4116 PF13475.6 KFM78740.1 - 0.084 12.6 0.1 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Ion_trans PF00520.31 KFM78741.1 - 1.3e-59 201.4 19.9 1.6e-59 201.1 19.9 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM78741.1 - 2.3e-09 36.4 16.2 5.7e-07 28.6 4.2 2.4 1 1 1 2 2 2 2 Polycystin cation channel GPHH PF16905.5 KFM78741.1 - 0.00028 20.6 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Tetraspanin PF00335.20 KFM78741.1 - 0.92 9.2 7.4 17 5.0 0.0 2.6 2 1 0 2 2 2 0 Tetraspanin family Ion_trans PF00520.31 KFM78742.1 - 4.4e-48 163.6 15.3 5.1e-48 163.4 15.3 1.0 1 0 0 1 1 1 1 Ion transport protein Na_trans_assoc PF06512.13 KFM78742.1 - 1.3e-08 35.3 3.1 1.9e-08 34.9 3.1 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated PKD_channel PF08016.12 KFM78742.1 - 0.0042 15.8 12.2 0.14 10.8 1.6 2.1 1 1 1 2 2 2 2 Polycystin cation channel DHHC PF01529.20 KFM78742.1 - 2 8.5 8.0 0.66 10.1 2.0 2.3 1 1 1 2 2 2 0 DHHC palmitoyltransferase Sds3 PF08598.11 KFM78743.1 - 3e-19 69.9 12.7 3e-19 69.9 12.7 1.5 2 0 0 2 2 2 1 Sds3-like Thyroglob_assoc PF16597.5 KFM78743.1 - 0.087 13.1 0.2 0.087 13.1 0.2 2.3 2 0 0 2 2 2 0 Thyroglobulin_1 repeat associated disordered domain Sigma70_ner PF04546.13 KFM78743.1 - 0.35 10.7 19.7 0.016 15.1 13.4 1.8 1 1 1 2 2 2 0 Sigma-70, non-essential region ABC_membrane_3 PF13748.6 KFM78743.1 - 0.39 9.9 0.9 0.61 9.3 0.9 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region dCache_2 PF08269.11 KFM78743.1 - 0.67 9.1 12.2 0.2 10.8 5.5 2.1 1 1 1 2 2 2 0 Cache domain DUF438 PF04282.13 KFM78743.1 - 1.5 8.9 6.2 0.64 10.0 1.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF438) Fungal_TACC PF12709.7 KFM78743.1 - 5.6 7.5 13.1 0.56 10.7 4.9 2.8 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins ApoC-I PF04691.12 KFM78743.1 - 7.8 6.5 8.5 0.51 10.3 0.6 2.7 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Peptidase_M28 PF04389.17 KFM78747.1 - 4e-08 33.2 0.0 6.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 KFM78747.1 - 3.1e-05 23.6 0.0 7.4e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Nicastrin Y_phosphatase PF00102.27 KFM78748.1 - 1.8e-50 171.7 0.1 2e-50 171.6 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Smim3 PF17307.2 KFM78748.1 - 0.02 14.4 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 Small integral membrane protein 3 Y_phosphatase PF00102.27 KFM78749.1 - 5.7e-38 130.8 0.1 6.3e-38 130.7 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM78749.1 - 7.2e-05 22.6 0.0 7.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM78749.1 - 0.00034 20.7 0.0 0.00036 20.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM78749.1 - 0.0056 16.8 0.0 0.0061 16.7 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Methyltransf_PK PF05891.12 KFM78749.1 - 0.03 13.8 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Y_phosphatase PF00102.27 KFM78750.1 - 1e-15 58.0 0.6 1.5e-15 57.4 0.6 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF433 PF04255.14 KFM78750.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF433) fn3 PF00041.21 KFM78751.1 - 0.032 14.6 0.0 0.094 13.1 0.0 1.7 1 1 1 2 2 2 0 Fibronectin type III domain CH PF00307.31 KFM78753.1 - 3.1e-12 46.6 3.2 4.8e-12 46.0 0.9 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain EB1 PF03271.17 KFM78753.1 - 2.8e-08 33.9 3.1 1.2e-07 31.9 1.2 2.7 2 1 0 2 2 2 1 EB1-like C-terminal motif CAMSAP_CH PF11971.8 KFM78753.1 - 0.00036 20.3 0.3 0.0014 18.4 0.1 2.1 2 0 0 2 2 2 1 CAMSAP CH domain PARP_reg PF02877.14 KFM78753.1 - 0.035 14.2 0.2 0.13 12.4 0.2 2.0 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain NleF_casp_inhib PF16809.5 KFM78753.1 - 0.037 14.0 0.3 0.084 12.8 0.1 1.6 2 0 0 2 2 2 0 NleF caspase inhibitor LMP PF04778.12 KFM78753.1 - 0.038 13.9 0.3 0.1 12.5 0.3 1.8 1 0 0 1 1 1 0 LMP repeated region Glyco_transf_92 PF01697.27 KFM78754.1 - 3.5e-06 26.9 0.3 3.5e-06 26.9 0.3 1.8 2 1 0 2 2 2 1 Glycosyltransferase family 92 Sugar_tr PF00083.24 KFM78755.1 - 3.9e-81 273.2 25.5 4.5e-81 273.0 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM78755.1 - 1.4e-30 106.4 29.3 1.4e-30 106.4 29.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily I-set PF07679.16 KFM78756.1 - 7.3e-87 285.6 0.0 2.2e-14 53.3 0.0 7.2 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM78756.1 - 3.6e-86 283.8 1.6 4.1e-14 52.9 0.0 7.4 7 0 0 7 7 7 7 Immunoglobulin domain Pkinase_Tyr PF07714.17 KFM78756.1 - 1.7e-68 230.7 0.2 2.5e-68 230.2 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.6 KFM78756.1 - 3.6e-60 200.2 2.9 1.9e-12 47.4 0.0 7.4 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 KFM78756.1 - 3e-50 168.3 3.3 4.5e-11 42.8 0.0 7.5 7 0 0 7 7 7 7 Immunoglobulin domain Pkinase PF00069.25 KFM78756.1 - 2.7e-29 102.3 0.0 4.2e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 KFM78756.1 - 1.1e-28 99.6 11.9 0.00012 22.2 0.1 11.1 7 5 1 8 8 8 6 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM78756.1 - 1.6e-18 66.0 0.0 0.00097 18.7 0.0 6.5 6 0 0 6 6 6 4 Immunoglobulin domain Ig_5 PF16681.5 KFM78756.1 - 2.3e-15 56.7 0.5 0.17 12.3 0.0 7.7 7 0 0 7 7 7 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM78756.1 - 3.4e-12 46.5 0.9 0.14 12.5 0.0 6.9 7 0 0 7 7 7 3 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFM78756.1 - 3.5e-10 39.8 0.0 0.035 14.2 0.0 6.0 5 1 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM78756.1 - 8.4e-10 38.6 0.1 1.3 9.1 0.0 6.3 7 0 0 7 7 6 3 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 KFM78756.1 - 0.0012 17.7 0.0 0.6 8.8 0.0 3.9 5 0 0 5 5 5 1 Alphaherpesvirus glycoprotein E BiPBP_C PF06832.12 KFM78756.1 - 0.009 16.0 0.0 3.6 7.7 0.0 3.4 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family TMEM51 PF15345.6 KFM78756.1 - 0.12 12.2 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Homeodomain PF00046.29 KFM78757.1 - 8.2e-19 67.2 6.6 1.4e-18 66.5 6.6 1.4 1 0 0 1 1 1 1 Homeodomain CIMR PF00878.18 KFM78760.1 - 0.0046 17.0 0.3 0.0052 16.9 0.3 1.1 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat DUF4820 PF16091.5 KFM78760.1 - 0.049 13.0 7.0 0.067 12.6 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3824 PF12868.7 KFM78760.1 - 0.17 12.5 2.1 0.25 12.0 2.1 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) AP3D1 PF06375.11 KFM78760.1 - 4 7.7 12.6 5.2 7.3 12.6 1.3 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 HCO3_cotransp PF00955.21 KFM78761.1 - 3.3e-146 488.1 12.4 7.7e-146 486.9 12.4 1.5 1 1 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFM78762.1 - 8.6e-95 317.6 0.0 1.2e-94 317.0 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain HCO3_cotransp PF00955.21 KFM78762.1 - 2.9e-46 158.4 1.1 3.6e-46 158.1 1.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family TLE_N PF03920.15 KFM78763.1 - 1.8e-38 131.6 8.7 2.8e-38 131.0 8.7 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 KFM78763.1 - 3.2e-19 68.9 20.5 0.0091 16.8 0.9 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM78763.1 - 4.8e-08 33.2 0.0 0.3 11.4 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM78763.1 - 0.012 14.9 0.0 5.8 6.1 0.1 2.6 2 1 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 KFM78763.1 - 0.017 13.7 0.0 2.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain MAM PF00629.23 KFM78764.1 - 2e-14 53.8 0.0 2.8e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KFM78765.1 - 4.1e-22 78.8 0.0 5.1e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KFM78766.1 - 4.4e-38 130.7 0.0 8.6e-21 74.5 0.0 2.9 2 1 0 2 2 2 2 MAM domain, meprin/A5/mu Sushi PF00084.20 KFM78768.1 - 7.4e-11 42.5 2.2 1.4e-09 38.4 1.3 2.8 3 0 0 3 3 3 1 Sushi repeat (SCR repeat) Ig_3 PF13927.6 KFM78768.1 - 5.8e-05 23.6 1.6 0.017 15.7 0.1 3.0 2 1 1 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 KFM78768.1 - 0.00046 20.5 0.4 0.0029 17.9 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_5 PF16681.5 KFM78768.1 - 0.0012 19.2 0.5 0.34 11.3 0.1 2.7 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ig PF00047.25 KFM78768.1 - 0.0016 18.6 2.9 0.18 12.0 0.4 2.6 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFM78768.1 - 0.0059 16.6 0.3 0.082 13.0 0.2 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain DUF3127 PF11325.8 KFM78768.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) Lyx_isomer PF07385.12 KFM78768.1 - 0.074 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase Ig_4 PF16680.5 KFM78768.1 - 0.087 13.1 0.4 0.59 10.4 0.2 2.2 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain HRM PF02793.22 KFM78768.1 - 0.44 10.9 6.1 0.44 10.9 1.4 3.1 3 1 0 3 3 3 0 Hormone receptor domain Trypsin PF00089.26 KFM78769.1 - 1.2e-52 179.0 0.0 1.3e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM78769.1 - 0.00013 22.9 0.0 0.00022 22.1 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM78769.1 - 0.12 12.8 0.2 8.5 6.8 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1986) FKBP_C PF00254.28 KFM78770.1 - 5.9e-19 68.2 0.0 1.8e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 KFM78770.1 - 1.1e-10 40.8 5.5 0.00066 19.6 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM78770.1 - 4.8e-09 35.6 9.4 0.0041 16.9 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM78770.1 - 1.2e-08 34.5 6.5 0.00031 20.7 0.5 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM78770.1 - 7e-07 29.4 0.5 7e-05 23.0 0.5 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM78770.1 - 3.8e-06 27.3 1.6 0.01 16.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM78770.1 - 3e-05 23.6 0.0 0.1 12.3 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_6 PF13174.6 KFM78770.1 - 0.0001 22.7 2.8 0.59 10.9 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM78770.1 - 0.00012 22.2 3.3 0.0011 19.1 0.2 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFM78770.1 - 0.00028 21.0 1.0 0.47 10.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM78770.1 - 0.0069 17.0 0.0 0.11 13.1 0.0 2.4 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM78770.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM78770.1 - 0.016 15.2 1.4 0.52 10.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM78770.1 - 0.027 15.3 0.0 16 6.6 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFM78770.1 - 0.048 13.7 0.3 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Stork_head PF10264.9 KFM78770.1 - 0.15 12.2 0.4 3.7 7.8 0.0 2.8 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain Ycf34 PF10718.9 KFM78770.1 - 0.25 12.0 1.9 1.1 10.0 0.2 2.5 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 DUF2045 PF09741.9 KFM78771.1 - 7.5e-89 297.1 0.2 1.3e-88 296.4 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) Med15 PF09606.10 KFM78772.1 - 2.8e-103 347.2 33.9 2.8e-103 347.2 33.9 2.0 1 1 1 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal RWD PF05773.22 KFM78772.1 - 0.02 15.1 0.2 0.049 13.9 0.2 1.6 1 0 0 1 1 1 0 RWD domain HAUS5 PF14817.6 KFM78772.1 - 0.059 12.1 0.1 0.67 8.6 0.0 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 5 DUF5339 PF17274.2 KFM78772.1 - 2.2 9.2 5.2 47 4.9 1.0 3.3 2 1 0 2 2 2 0 Family of unknown function (DUF5339) C2 PF00168.30 KFM78773.1 - 0.0013 18.9 0.3 0.025 14.9 0.0 2.5 2 0 0 2 2 2 1 C2 domain Ebp2 PF05890.12 KFM78773.1 - 0.071 12.7 0.5 0.21 11.1 0.5 1.8 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 DUF1115 PF06544.12 KFM78773.1 - 0.096 12.8 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Apolipoprotein PF01442.18 KFM78773.1 - 0.12 12.3 0.2 0.42 10.5 0.1 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Rubrerythrin PF02915.17 KFM78773.1 - 0.14 12.5 1.5 0.9 9.9 0.1 3.0 3 0 0 3 3 3 0 Rubrerythrin Sirohm_synth_C PF14823.6 KFM78773.1 - 0.2 11.3 2.6 0.47 10.1 0.5 2.5 1 1 1 2 2 2 0 Sirohaem biosynthesis protein C-terminal F_actin_bind PF08919.10 KFM78773.1 - 0.41 10.8 8.3 0.35 11.0 1.2 3.7 2 1 1 3 3 3 0 F-actin binding DUF4844 PF16133.5 KFM78773.1 - 0.98 10.0 5.1 6.9 7.2 0.2 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4844) TRP_2 PF08344.11 KFM78776.1 - 1.5e-26 92.3 3.1 2.8e-26 91.5 3.1 1.4 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 KFM78776.1 - 2.6e-10 40.8 0.7 3.1e-09 37.3 0.7 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM78776.1 - 8.3e-07 28.8 2.2 0.075 13.6 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFM78776.1 - 8.8e-07 29.1 0.2 0.01 16.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM78776.1 - 1.4e-06 28.7 0.3 0.011 16.3 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM78776.1 - 1.4e-05 25.3 0.9 0.0048 17.3 0.1 3.4 2 1 1 3 3 3 1 Ankyrin repeat NPC1_N PF16414.5 KFM78776.1 - 0.072 12.6 1.6 0.14 11.7 1.6 1.4 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus Glyco_transf_8 PF01501.20 KFM78777.1 - 2.5e-13 50.2 1.4 3.1e-13 49.9 1.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFM78777.1 - 0.026 14.0 0.6 0.051 13.0 0.6 1.5 1 1 0 1 1 1 0 Glucosyltransferase 24 DUF4579 PF15158.6 KFM78777.1 - 0.033 13.9 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) MFS_1_like PF12832.7 KFM78778.1 - 1.1e-52 179.3 10.0 1.1e-52 179.2 10.0 1.0 1 0 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 KFM78778.1 - 2.7e-09 36.5 7.1 3.5e-09 36.1 7.1 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 KFM78778.1 - 0.0066 15.3 10.1 0.0043 15.9 7.7 1.6 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_MOT1 PF16983.5 KFM78778.1 - 0.008 16.6 1.0 0.008 16.6 1.0 1.9 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily MFS_1 PF07690.16 KFM78778.1 - 0.23 10.4 21.1 0.55 9.1 21.1 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily MFS_1_like PF12832.7 KFM78779.1 - 7.4e-85 285.1 21.3 8.5e-85 284.9 21.3 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM78779.1 - 1.6e-15 56.9 41.8 1.4e-08 34.1 18.2 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFM78779.1 - 1e-07 31.3 11.3 1e-07 31.3 11.3 2.1 2 0 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 KFM78779.1 - 0.00059 18.7 27.0 0.0052 15.6 4.1 3.4 2 1 1 3 3 3 2 LacY proton/sugar symporter IF4E PF01652.18 KFM78780.1 - 6.2e-56 188.6 0.1 7.4e-56 188.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3660 PF12398.8 KFM78780.1 - 0.06 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Receptor serine/threonine kinase AMP-binding PF00501.28 KFM78781.1 - 8.1e-96 321.2 0.0 1.1e-95 320.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM78781.1 - 0.00041 21.3 0.0 0.0011 19.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RILP PF11461.8 KFM78782.1 - 5.3e-12 45.8 0.3 7.7e-12 45.2 0.3 1.3 1 0 0 1 1 1 1 Rab interacting lysosomal protein Cytokin_check_N PF10407.9 KFM78782.1 - 0.07 13.1 0.4 3.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus LRRFIP PF09738.9 KFM78782.1 - 0.082 12.4 0.2 0.098 12.1 0.2 1.1 1 0 0 1 1 1 0 LRRFIP family Pox_A_type_inc PF04508.12 KFM78782.1 - 0.093 12.6 0.9 0.25 11.3 0.9 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat 7tm_1 PF00001.21 KFM78783.1 - 3.9e-15 55.9 1.3 3.9e-15 55.9 1.3 1.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM78783.1 - 0.057 12.8 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx LAP1C PF05609.12 KFM78783.1 - 0.8 8.7 13.0 0.083 12.0 2.6 2.0 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) GDPD_2 PF13653.6 KFM78785.1 - 0.031 14.7 0.1 0.05 14.1 0.1 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Ig_3 PF13927.6 KFM78786.1 - 1.3e-15 57.7 0.0 3.8e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM78786.1 - 2.3e-12 46.8 0.0 4.5e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFM78786.1 - 2.1e-10 40.7 0.0 1e-07 32.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM78786.1 - 6.3e-10 39.3 0.0 1.3e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM78786.1 - 2e-05 24.7 0.1 0.022 14.9 0.0 2.7 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM78786.1 - 0.00099 18.6 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM78786.1 - 0.046 13.8 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFM78786.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 HTH_Tnp_Tc3_2 PF01498.18 KFM78790.1 - 1.1e-10 41.6 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Transposase PARG_cat PF05028.14 KFM78792.1 - 7.4e-32 111.0 0.0 9.5e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) LANC_like PF05147.13 KFM78793.1 - 1.9e-07 30.0 0.0 2.4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein LANC_like PF05147.13 KFM78794.1 - 5.9e-50 169.8 0.0 6.5e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 KFM78794.1 - 0.00023 20.7 0.0 0.059 12.9 0.0 2.2 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 KFM78794.1 - 0.097 11.7 0.0 0.42 9.6 0.1 1.9 1 1 2 3 3 3 0 Glycosyl Hydrolase Family 88 DNApol_Exo PF18136.1 KFM78795.1 - 6.6e-20 71.4 0.0 7.1e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KFM78798.1 - 2.6e-48 165.0 0.0 3.2e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_lambd_f PF10391.9 KFM78798.1 - 0.12 12.2 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Integrase_Zn PF02022.19 KFM78798.1 - 0.15 12.1 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Integrase Zinc binding domain Menin PF05053.13 KFM78799.1 - 2.9e-16 59.0 0.3 2.9e-16 59.0 0.3 1.0 1 0 0 1 1 1 1 Menin Menin PF05053.13 KFM78800.1 - 1e-61 209.3 0.1 1.1e-61 209.1 0.1 1.0 1 0 0 1 1 1 1 Menin TPR_2 PF07719.17 KFM78800.1 - 0.012 15.6 1.2 0.033 14.3 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM78800.1 - 0.031 14.9 0.2 0.074 13.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM78800.1 - 0.11 12.7 2.6 0.16 12.3 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM78801.1 - 3.9e-64 210.0 45.8 5.3e-08 32.3 0.0 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 KFM78801.1 - 1.9e-55 180.6 37.3 1.3e-07 31.1 0.1 9.8 10 0 0 10 10 10 9 Tetratricopeptide repeat STI1 PF17830.1 KFM78801.1 - 7.3e-41 137.9 7.3 3.9e-22 77.9 0.1 3.0 2 0 0 2 2 2 2 STI1 domain TPR_11 PF13414.6 KFM78801.1 - 4e-39 132.0 28.1 8.1e-10 38.2 0.0 8.2 5 3 4 9 9 9 5 TPR repeat TPR_8 PF13181.6 KFM78801.1 - 3.7e-33 110.9 30.5 3e-05 23.9 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.6 KFM78801.1 - 3.1e-27 92.9 8.8 0.00099 19.7 0.0 8.4 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFM78801.1 - 6.1e-25 87.6 9.3 0.0004 21.0 0.2 6.6 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFM78801.1 - 7.2e-22 77.5 27.2 1.3e-07 31.8 0.8 8.4 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFM78801.1 - 2.2e-18 65.2 26.6 0.0011 19.1 0.2 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFM78801.1 - 6.3e-16 58.6 18.2 0.013 16.0 0.1 6.8 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFM78801.1 - 8.9e-13 47.7 21.5 0.076 12.9 0.7 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFM78801.1 - 8.7e-11 41.1 18.2 0.031 14.3 0.3 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFM78801.1 - 9.9e-11 41.6 17.8 0.12 13.0 2.1 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFM78801.1 - 1.5e-09 37.8 1.8 0.0068 16.5 0.1 5.7 3 3 3 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM78801.1 - 3.3e-08 33.5 22.0 0.11 12.5 0.1 7.9 7 1 1 8 8 8 3 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KFM78801.1 - 4.5e-06 26.6 29.8 0.17 12.0 0.2 7.1 6 0 0 6 6 6 2 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 KFM78801.1 - 1e-05 25.7 25.7 0.063 13.5 0.3 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFM78801.1 - 1.1e-05 24.8 7.4 0.43 9.8 0.3 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 KFM78801.1 - 0.00015 20.9 19.4 0.11 11.4 0.1 4.9 2 1 3 5 5 5 3 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 KFM78801.1 - 0.0048 16.6 21.6 0.005 16.6 3.2 5.0 2 2 2 4 4 4 1 Tetratricopeptide repeat-like domain BEN PF10523.9 KFM78801.1 - 0.01 16.0 0.0 0.058 13.6 0.0 2.3 1 0 0 1 1 1 0 BEN domain TPR_MalT PF17874.1 KFM78801.1 - 0.012 15.0 0.1 0.41 10.0 0.0 2.8 2 0 0 2 2 2 0 MalT-like TPR region TOM20_plant PF06552.12 KFM78801.1 - 0.022 14.5 7.4 0.58 9.9 0.0 4.1 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 G3P_antiterm PF04309.12 KFM78801.1 - 0.07 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator TPR_20 PF14561.6 KFM78801.1 - 0.11 12.9 9.8 0.19 12.0 0.3 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFM78801.1 - 0.35 10.4 14.0 4.2 6.9 0.1 6.0 6 1 0 6 6 6 0 SHNi-TPR TPR_3 PF07720.12 KFM78801.1 - 0.43 10.6 27.3 3.6 7.7 0.4 7.1 7 1 0 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.17 KFM78801.1 - 1.6 9.1 10.5 6.2 7.3 0.1 4.6 3 3 1 4 4 4 0 Bacterial transcriptional activator domain DUF4298 PF14131.6 KFM78801.1 - 2.7 8.0 8.2 0.21 11.5 1.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4298) HemY_N PF07219.13 KFM78801.1 - 5.3 7.3 9.3 21 5.3 0.1 4.2 5 0 0 5 5 4 0 HemY protein N-terminus RGS PF00615.19 KFM78802.1 - 6.8e-36 123.1 2.1 1.1e-35 122.5 2.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Curto_V3 PF07436.11 KFM78802.1 - 0.053 13.9 0.2 2.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Curtovirus V3 protein Band_7 PF01145.25 KFM78803.1 - 5.9e-22 78.5 0.0 5.9e-22 78.5 0.0 2.2 3 0 0 3 3 3 1 SPFH domain / Band 7 family BING4CT PF08149.11 KFM78804.1 - 2.2e-38 129.9 0.0 3.1e-35 119.8 0.0 3.4 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 KFM78804.1 - 3.9e-06 27.5 0.0 0.033 15.1 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM78804.1 - 0.00016 21.9 0.0 6.2 7.2 0.0 4.5 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Thiolase_N PF00108.23 KFM78805.1 - 2.7e-19 69.6 0.5 4.7e-18 65.5 0.3 2.4 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFM78805.1 - 1.4e-11 44.1 1.0 3.1e-10 39.7 0.0 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFM78805.1 - 0.0022 17.6 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFM78805.1 - 0.0029 17.4 1.4 0.031 14.1 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 KFM78805.1 - 0.021 14.8 0.1 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 KFM78805.1 - 0.026 13.2 0.1 0.062 12.0 0.0 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) HSP90 PF00183.18 KFM78806.1 - 1.7e-233 776.2 34.2 2e-233 776.0 34.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFM78806.1 - 7.1e-14 52.3 0.0 1.6e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFM78806.1 - 1e-11 44.8 0.1 2.8e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRAP_alpha PF03896.16 KFM78806.1 - 0.12 11.6 7.9 0.25 10.5 7.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 KFM78806.1 - 2 6.6 15.6 4 5.6 15.6 1.4 1 0 0 1 1 1 0 CDC45-like protein MBF1 PF08523.10 KFM78807.1 - 7.2e-27 93.7 2.9 7.2e-27 93.7 2.9 1.8 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KFM78807.1 - 4.7e-12 45.8 0.2 7.9e-12 45.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KFM78807.1 - 8.5e-06 26.0 0.0 1.5e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KFM78807.1 - 0.00036 20.5 0.4 0.00061 19.8 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Dor1 PF04124.12 KFM78807.1 - 0.012 14.3 1.7 0.013 14.2 1.7 1.1 1 0 0 1 1 1 0 Dor1-like family HTH_38 PF13936.6 KFM78807.1 - 0.044 13.6 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TMEM237 PF15383.6 KFM78807.1 - 0.13 11.3 0.4 0.16 11.0 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 zf-DNL PF05180.12 KFM78808.1 - 3.8e-28 97.2 0.3 7.3e-28 96.3 0.3 1.5 1 0 0 1 1 1 1 DNL zinc finger Cript PF10235.9 KFM78808.1 - 0.078 13.6 2.0 0.12 12.9 2.0 1.5 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Phosphoesterase PF04185.14 KFM78808.1 - 0.17 11.0 0.1 5.3 6.1 0.0 2.0 1 1 1 2 2 2 0 Phosphoesterase family zf-H2C2_2 PF13465.6 KFM78809.1 - 4.8e-14 52.0 10.1 1.2e-05 25.5 0.6 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78809.1 - 4.5e-10 39.4 15.8 2e-06 27.9 1.1 2.6 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-met PF12874.7 KFM78809.1 - 5.9e-10 39.2 11.7 8.8e-05 22.8 1.5 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM78809.1 - 3.2e-09 36.9 13.5 0.00013 22.5 0.8 2.6 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM78809.1 - 9.2e-07 29.0 12.5 0.00074 19.7 2.3 2.8 1 1 2 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM78809.1 - 0.00017 21.5 9.5 0.012 15.6 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM78809.1 - 0.00022 20.9 1.5 0.023 14.4 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-RRPl_C4 PF17026.5 KFM78809.1 - 0.0023 18.0 3.1 0.0024 18.0 3.1 1.1 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type SPARC_Ca_bdg PF10591.9 KFM78809.1 - 0.0045 17.3 0.5 0.0057 17.0 0.5 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region zf-Sec23_Sec24 PF04810.15 KFM78809.1 - 0.012 15.7 1.7 0.87 9.7 0.1 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM78809.1 - 0.015 14.9 2.7 0.88 9.2 0.1 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain Zn-C2H2_12 PF18112.1 KFM78809.1 - 0.02 15.3 3.5 0.24 11.9 0.5 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 KFM78809.1 - 0.026 14.8 8.9 0.22 11.9 1.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFM78809.1 - 0.038 13.8 2.5 0.038 13.8 2.5 2.3 3 0 0 3 3 2 0 zinc-finger C2H2-type HNH_5 PF14279.6 KFM78809.1 - 0.05 13.5 5.2 0.21 11.5 5.3 1.9 1 1 0 1 1 1 0 HNH endonuclease BolA PF01722.18 KFM78809.1 - 0.076 13.3 0.3 3.5 8.0 0.1 2.0 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_9 PF16293.5 KFM78809.1 - 0.08 12.8 2.3 5.5 6.9 0.1 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM78809.1 - 0.095 12.8 4.5 0.13 12.4 4.5 1.3 1 0 0 1 1 1 0 FYVE zinc finger Rep_fac-A_C PF08646.10 KFM78809.1 - 0.095 12.4 3.6 1.8 8.3 0.1 2.0 1 1 1 2 2 2 0 Replication factor-A C terminal domain C1_4 PF07975.12 KFM78809.1 - 0.096 12.9 6.4 0.28 11.5 6.4 1.7 1 1 1 2 2 2 0 TFIIH C1-like domain C5HCH PF17982.1 KFM78809.1 - 0.12 12.6 5.9 1.8 8.7 2.2 2.2 2 0 0 2 2 2 0 NSD Cys-His rich domain zf_UBZ PF18439.1 KFM78809.1 - 0.12 12.0 4.9 3.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 KFM78809.1 - 0.13 12.7 0.4 0.13 12.7 0.4 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-DBF PF07535.12 KFM78809.1 - 0.19 11.9 9.0 1.5 9.0 1.1 2.5 1 1 1 2 2 2 0 DBF zinc finger zf-C2HC_2 PF13913.6 KFM78809.1 - 0.21 11.5 4.7 0.35 10.8 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type XPA_N PF01286.18 KFM78809.1 - 0.27 11.3 5.3 2.5 8.2 0.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_8 PF15909.5 KFM78809.1 - 0.81 10.0 6.5 4.6 7.6 6.5 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon TRAF6_Z2 PF18048.1 KFM78809.1 - 1.7 8.8 6.8 3.6 7.8 0.4 2.9 3 1 0 3 3 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-FCS PF06467.14 KFM78810.1 - 1.1e-19 70.1 93.9 8.8e-06 25.6 0.6 9.9 9 0 0 9 9 9 8 MYM-type Zinc finger with FCS sequence motif Pox_A3L PF05288.11 KFM78810.1 - 1.3 9.1 4.0 2.9 8.0 0.1 3.2 3 0 0 3 3 3 0 Poxvirus A3L Protein DUF3504 PF12012.8 KFM78811.1 - 9.5e-48 162.2 1.7 1.1e-47 162.0 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) Coq4 PF05019.13 KFM78812.1 - 5.6e-83 277.6 0.0 6.4e-83 277.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Med23 PF11573.8 KFM78813.1 - 2.1e-65 221.2 1.2 2.4e-65 221.0 1.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 PIG-S PF10510.9 KFM78813.1 - 0.032 13.1 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Med23 PF11573.8 KFM78814.1 - 1.1e-213 712.5 2.3 1.2e-213 712.3 2.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Med23 PF11573.8 KFM78815.1 - 8e-112 375.0 2.8 8.9e-112 374.9 2.8 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Med23 PF11573.8 KFM78816.1 - 2.1e-109 367.0 0.0 2.4e-109 366.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 DUF3289 PF11692.8 KFM78816.1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3289) RAI1 PF08652.11 KFM78816.1 - 0.29 11.3 1.4 2.6 8.3 0.0 2.8 3 0 0 3 3 3 0 RAI1 like PD-(D/E)XK nuclease Ada3 PF10198.9 KFM78817.1 - 4e-19 69.1 10.2 4e-19 69.1 10.2 2.3 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 JmjN PF02375.17 KFM78817.1 - 0.076 13.0 0.5 0.22 11.5 0.5 1.8 1 1 0 1 1 1 0 jmjN domain Mito_carr PF00153.27 KFM78818.1 - 5.5e-52 173.7 4.1 2.7e-22 78.5 0.1 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KFM78818.1 - 0.0011 18.2 1.2 0.004 16.4 1.2 2.2 1 1 0 1 1 1 1 Gammaproteobacterial serine protease Keratin_2_head PF16208.5 KFM78819.1 - 0.13 12.4 23.6 0.17 12.0 23.6 1.2 1 0 0 1 1 1 0 Keratin type II head Glyco_transf_54 PF04666.13 KFM78820.1 - 2.3e-123 410.7 1.8 3.5e-123 410.1 1.8 1.2 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region COG5 PF10392.9 KFM78820.1 - 0.11 12.7 0.4 0.37 11.0 0.0 2.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 SSF PF00474.17 KFM78821.1 - 1.1e-27 97.0 12.6 1.4e-27 96.6 12.6 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF997 PF06196.12 KFM78821.1 - 2.1 8.4 8.6 0.35 10.9 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF997) SSF PF00474.17 KFM78822.1 - 0.035 13.0 0.2 0.035 13.0 0.2 1.0 1 0 0 1 1 1 0 Sodium:solute symporter family DDE_Tnp_IS1595 PF12762.7 KFM78824.1 - 6.9e-09 35.9 0.0 8.1e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.6 KFM78824.1 - 0.0096 15.7 0.0 0.021 14.6 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-C3HC4 PF00097.25 KFM78825.1 - 2.1e-08 33.9 3.3 2.4e-08 33.7 3.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM78825.1 - 1.9e-07 31.0 2.3 1.8e-05 24.6 0.4 2.0 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM78825.1 - 3.6e-07 30.2 3.6 4.7e-07 29.9 3.6 1.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFM78825.1 - 4.4e-07 30.1 3.7 4.9e-07 30.0 3.7 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM78825.1 - 5.8e-07 29.4 3.3 6.9e-07 29.1 3.3 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM78825.1 - 3e-06 27.0 4.2 3.9e-06 26.6 4.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM78825.1 - 4.5e-06 26.4 1.5 5.3e-06 26.2 1.5 1.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFM78825.1 - 9.4e-06 25.4 2.3 1.1e-05 25.2 2.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFM78825.1 - 5.1e-05 23.0 2.7 6e-05 22.8 2.7 1.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFM78825.1 - 0.00016 21.9 2.5 0.00019 21.6 2.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KFM78825.1 - 0.00048 19.9 1.8 0.00058 19.6 1.8 1.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFM78825.1 - 0.00073 19.6 0.8 0.0008 19.5 0.8 1.1 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KFM78825.1 - 0.0028 17.7 0.6 0.0031 17.5 0.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2 PF00096.26 KFM78825.1 - 0.0043 17.4 0.2 0.0043 17.4 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-P11 PF03854.14 KFM78825.1 - 0.0061 16.2 1.4 0.0076 15.9 1.4 1.2 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_6 PF14835.6 KFM78825.1 - 0.0063 16.4 0.7 0.0076 16.1 0.7 1.1 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 KFM78825.1 - 0.011 15.7 1.9 0.012 15.5 1.9 1.0 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prim_Zn_Ribbon PF08273.12 KFM78825.1 - 0.061 13.6 5.0 1.3 9.4 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-C2H2_4 PF13894.6 KFM78825.1 - 0.076 13.9 5.3 0.1 13.5 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 KFM78825.1 - 0.08 13.1 3.1 1.3 9.2 0.3 2.0 1 1 1 2 2 2 0 FYVE zinc finger PRMT5_C PF17286.2 KFM78828.1 - 0.0003 20.7 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PrmA PF06325.13 KFM78829.1 - 2.2e-07 30.5 0.6 3.7e-07 29.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFM78829.1 - 3.5e-05 23.7 0.0 9.8e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM78829.1 - 3.7e-05 24.4 0.8 0.00016 22.3 0.2 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM78829.1 - 0.00015 21.6 0.2 0.00038 20.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFM78829.1 - 0.0011 18.0 0.1 0.0016 17.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KFM78829.1 - 0.0046 16.5 0.1 0.0088 15.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain zf-C2H2_2 PF12756.7 KFM78829.1 - 0.0054 17.1 1.2 0.0054 17.1 1.2 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Methyltransf_11 PF08241.12 KFM78829.1 - 0.037 14.7 0.1 0.12 13.1 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFM78829.1 - 0.11 12.5 0.5 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 KFM78829.1 - 0.15 11.8 0.2 0.35 10.6 0.1 1.8 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PDEase_I PF00233.19 KFM78831.1 - 1.9e-65 220.9 3.3 3e-62 210.5 0.0 3.1 3 0 0 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase BTB PF00651.31 KFM78832.1 - 3.6e-14 52.9 0.0 6.5e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM78832.1 - 2.2e-06 27.7 0.2 6.4e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch CUE PF02845.16 KFM78833.1 - 3.5e-10 39.4 0.0 6.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain C2 PF00168.30 KFM78833.1 - 6.2e-09 36.1 0.0 9.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain HTH_8 PF02954.19 KFM78833.1 - 0.0049 16.6 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family zf-CCHC PF00098.23 KFM78834.1 - 4.4e-05 23.3 4.4 0.00011 22.1 4.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Hydrolase PF00702.26 KFM78835.1 - 4.5e-17 63.0 0.0 6e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM78835.1 - 1.8e-14 54.6 0.0 3.2e-14 53.8 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFM78835.1 - 5.6e-05 22.8 0.0 8.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 KFM78835.1 - 0.0015 18.6 0.0 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KFM78835.1 - 0.0039 16.6 0.0 0.06 12.7 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase_6 PF13344.6 KFM78835.1 - 0.0076 16.3 0.0 0.043 13.9 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KFM78835.1 - 0.019 14.6 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.12 KFM78835.1 - 0.031 14.0 0.0 0.12 12.1 0.0 1.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DUF1378 PF07125.11 KFM78835.1 - 0.093 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Ribosomal_S5_C PF03719.15 KFM78836.1 - 1.9e-22 78.5 0.0 3.4e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KFM78836.1 - 1.6e-13 50.4 1.2 3.2e-13 49.5 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain adh_short PF00106.25 KFM78837.1 - 1.4e-87 292.3 0.0 4.6e-43 147.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFM78837.1 - 5e-58 196.4 0.0 1.4e-29 103.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM78837.1 - 6.6e-13 49.0 0.0 7.5e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 KR domain DUF1776 PF08643.10 KFM78837.1 - 0.00019 20.9 0.0 0.35 10.2 0.0 3.5 3 1 0 3 3 3 2 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KFM78837.1 - 0.00033 20.2 0.1 0.014 14.9 0.0 3.1 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KFM78837.1 - 0.00083 19.1 0.0 0.53 10.1 0.0 2.8 2 0 0 2 2 2 2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aminotran_3 PF00202.21 KFM78838.1 - 9e-120 400.0 0.0 1.1e-119 399.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFM78838.1 - 0.01 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II ATP_synt_H PF05493.13 KFM78839.1 - 5.3e-25 87.7 10.6 6.4e-25 87.4 10.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit H HTH_48 PF17906.1 KFM78840.1 - 0.00017 21.6 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_24 PF13412.6 KFM78840.1 - 0.024 14.2 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GerE PF00196.19 KFM78840.1 - 0.08 12.5 0.2 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family CcmH PF03918.14 KFM78840.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.4 1 1 0 1 1 1 0 Cytochrome C biogenesis protein Integrase_Zn PF02022.19 KFM78840.1 - 0.14 12.2 0.3 0.22 11.5 0.3 1.3 1 0 0 1 1 1 0 Integrase Zinc binding domain Clathrin PF00637.20 KFM78842.1 - 5.3e-20 71.8 40.0 0.00079 19.3 0.1 9.4 5 4 4 10 10 10 7 Region in Clathrin and VPS TPR_12 PF13424.6 KFM78842.1 - 1e-08 35.4 31.6 0.083 13.2 0.3 11.4 7 3 3 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM78842.1 - 7.2e-08 32.6 24.0 21 6.3 0.4 12.0 8 4 4 12 12 11 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM78842.1 - 2.1e-05 24.2 33.7 1.2 9.3 0.2 11.7 9 4 2 11 11 11 3 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KFM78842.1 - 0.0029 16.7 0.6 0.0029 16.7 0.6 4.3 5 2 1 6 6 6 1 Coatomer WD associated region ANAPC3 PF12895.7 KFM78842.1 - 0.0038 17.4 25.6 3 8.1 0.1 9.4 6 3 1 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 KFM78842.1 - 0.044 13.8 27.5 2.4 8.1 0.1 7.1 6 2 1 7 7 6 0 Mad3/BUB1 homology region 1 Phage_T7_tail PF03906.14 KFM78842.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Phage T7 tail fibre protein Cas9-BH PF16593.5 KFM78842.1 - 0.098 12.4 1.3 0.25 11.1 1.3 1.6 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 TPR_19 PF14559.6 KFM78842.1 - 0.2 12.2 18.4 18 5.9 0.2 8.5 6 4 3 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM78842.1 - 1.1 10.0 30.8 0.54 11.0 0.1 8.8 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM78842.1 - 1.1 9.0 21.7 3 7.6 0.1 7.5 6 0 0 6 6 6 0 TPR repeat TPR_1 PF00515.28 KFM78842.1 - 1.2 9.1 52.7 1.6 8.7 1.2 12.7 11 3 4 15 15 15 0 Tetratricopeptide repeat Pep3_Vps18 PF05131.14 KFM78842.1 - 2.5 7.9 5.5 26 4.6 0.2 4.1 4 0 0 4 4 4 0 Pep3/Vps18/deep orange family TPR_2 PF07719.17 KFM78842.1 - 2.6 8.4 60.4 0.6 10.4 0.5 13.9 15 3 3 19 19 16 0 Tetratricopeptide repeat DUF1771 PF08590.10 KFM78842.1 - 5.5 7.4 8.0 11 6.5 0.4 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1771) Vps39_1 PF10366.9 KFM78842.1 - 5.9 7.2 20.1 31 4.9 0.0 6.6 5 1 2 7 7 7 0 Vacuolar sorting protein 39 domain 1 ANAPC4_WD40 PF12894.7 KFM78843.1 - 8.9e-12 45.2 0.3 0.0011 19.2 0.0 3.7 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM78843.1 - 2.8e-09 37.5 0.7 0.0064 17.3 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 KFM78843.1 - 0.0092 15.9 0.0 0.043 13.7 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A AdHead_fibreRBD PF16812.5 KFM78843.1 - 0.053 13.4 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 C-terminal head domain of the fowl adenovirus type 1 long fibre Ge1_WD40 PF16529.5 KFM78843.1 - 0.095 11.6 0.1 0.42 9.5 0.1 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Myb_DNA-binding PF00249.31 KFM78844.1 - 2.1e-06 27.8 0.1 6.2e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM78844.1 - 0.084 13.1 2.2 0.48 10.7 0.0 2.9 2 2 1 3 3 3 0 Myb-like DNA-binding domain E3_UFM1_ligase PF09743.9 KFM78845.1 - 1.5e-108 362.6 0.1 2.5e-108 361.8 0.1 1.4 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 Pns11_12 PF17464.2 KFM78845.1 - 0.2 11.3 8.0 0.51 10.0 8.0 1.6 1 0 0 1 1 1 0 Non-structural protein 11 and 12 CBM_14 PF01607.24 KFM78846.1 - 1.5e-11 44.2 5.5 2.4e-11 43.6 5.5 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Guanylate_kin PF00625.21 KFM78848.1 - 3.4e-66 222.4 0.0 4.6e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 KFM78848.1 - 3.1e-08 34.2 0.0 7.9e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM78848.1 - 5.7e-08 33.0 0.0 9.6e-07 29.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFM78848.1 - 0.00011 22.7 0.0 0.00019 22.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KFM78848.1 - 0.00011 22.5 0.0 0.00034 20.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFM78848.1 - 0.00013 22.1 0.0 0.00024 21.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFM78848.1 - 0.0002 21.8 0.0 0.0005 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KFM78848.1 - 0.00059 20.2 0.0 0.0012 19.2 0.0 1.7 1 1 0 1 1 1 1 RNA helicase Rad17 PF03215.15 KFM78848.1 - 0.0006 19.8 0.0 0.00095 19.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KFM78848.1 - 0.0021 18.0 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ATPase_2 PF01637.18 KFM78848.1 - 0.0026 17.7 0.1 0.0038 17.2 0.1 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KFM78848.1 - 0.0038 16.9 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain dNK PF01712.19 KFM78848.1 - 0.004 17.0 0.1 0.89 9.4 0.0 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_7 PF12775.7 KFM78848.1 - 0.0057 16.2 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_21 PF13304.6 KFM78848.1 - 0.008 16.0 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KFM78848.1 - 0.0084 16.0 0.0 0.021 14.8 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KFM78848.1 - 0.01 16.3 0.3 0.097 13.1 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KFM78848.1 - 0.012 15.2 0.0 0.087 12.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KFM78848.1 - 0.017 15.5 0.2 0.71 10.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KFM78848.1 - 0.02 14.3 0.1 0.063 12.6 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 KFM78848.1 - 0.024 14.7 0.1 0.067 13.2 0.0 2.0 2 1 0 2 2 1 0 AAA domain Thymidylate_kin PF02223.17 KFM78848.1 - 0.024 14.3 0.1 8.7 6.0 0.0 2.5 2 1 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.6 KFM78848.1 - 0.028 14.6 0.1 0.13 12.5 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.6 KFM78848.1 - 0.031 14.8 2.9 0.033 14.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KFM78848.1 - 0.041 12.9 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 KFM78848.1 - 0.068 12.9 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KFM78848.1 - 0.075 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family DUF87 PF01935.17 KFM78848.1 - 0.12 12.5 0.0 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 KFM78848.1 - 0.12 11.6 0.0 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 KFM78848.1 - 0.15 12.1 0.0 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KFM78848.1 - 0.16 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Cation_ATPase_C PF00689.21 KFM78850.1 - 0.00081 19.2 1.1 0.00095 18.9 1.1 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFM78854.1 - 0.032 13.8 0.0 0.065 12.8 0.0 1.5 2 0 0 2 2 2 0 E1-E2 ATPase Endonuclea_NS_2 PF13930.6 KFM78854.1 - 0.18 11.9 0.1 0.26 11.4 0.1 1.1 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease DUF4837 PF16125.5 KFM78855.1 - 0.018 14.1 0.1 0.019 14.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) MMPL PF03176.15 KFM78855.1 - 0.025 13.5 0.0 0.029 13.3 0.0 1.0 1 0 0 1 1 1 0 MMPL family PsbH PF00737.20 KFM78855.1 - 0.073 12.8 0.7 0.11 12.3 0.7 1.2 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Ribosomal_L19 PF01245.20 KFM78856.1 - 1.4e-14 54.0 0.0 2.4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Pkinase PF00069.25 KFM78857.1 - 1e-60 205.3 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM78857.1 - 7.4e-23 81.2 0.0 1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM78857.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM78857.1 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM78857.1 - 0.046 12.7 0.2 0.094 11.6 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Methyltransf_8 PF05148.15 KFM78858.1 - 7.3e-20 71.8 0.5 1.5e-19 70.8 0.5 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase Synaptobrevin PF00957.21 KFM78859.1 - 3.7e-31 106.7 2.9 5.8e-31 106.1 2.9 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFM78859.1 - 3.3e-23 81.5 0.5 5.4e-23 80.8 0.5 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain EMP24_GP25L PF01105.24 KFM78859.1 - 0.021 14.8 2.4 0.053 13.4 2.4 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD RIFIN PF02009.16 KFM78859.1 - 0.023 14.6 0.8 0.023 14.6 0.8 1.2 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 KFM78859.1 - 0.056 13.8 1.2 0.095 13.0 1.2 1.4 1 0 0 1 1 1 0 Orf78 (ac78) LPD14 PF18827.1 KFM78859.1 - 0.057 13.7 0.1 0.095 13.0 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 14 Med21 PF11221.8 KFM78859.1 - 0.13 12.5 0.0 0.42 10.9 0.0 1.8 1 1 0 1 1 1 0 Subunit 21 of Mediator complex MSC PF09402.10 KFM78859.1 - 0.2 11.1 0.9 0.25 10.7 0.9 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PIP5K PF01504.18 KFM78861.1 - 3.7e-45 154.3 1.9 2e-36 125.7 1.2 2.7 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KFM78861.1 - 8.5e-14 51.0 0.0 1.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KFM78862.1 - 2.4e-16 59.6 15.8 4.3e-16 58.8 15.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger DEP PF00610.21 KFM78862.1 - 1.7e-12 47.2 0.0 3.9e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Abhydrolase_1 PF00561.20 KFM78863.1 - 3.9e-07 30.0 0.1 1.5e-06 28.1 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM78863.1 - 5.7e-06 27.1 0.0 7.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KFM78863.1 - 1.7e-05 25.1 0.1 3e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KFM78863.1 - 0.0033 17.2 0.0 0.0087 15.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM78863.1 - 0.0074 15.6 0.0 0.012 14.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFM78863.1 - 0.008 14.9 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 Ndr family Palm_thioest PF02089.15 KFM78863.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase THAP PF05485.12 KFM78864.1 - 1.6e-07 32.1 0.4 1.8e-07 32.0 0.4 1.1 1 0 0 1 1 1 1 THAP domain NEMP PF10225.9 KFM78865.1 - 2.1e-19 70.2 2.6 2.5e-19 70.0 2.6 1.1 1 0 0 1 1 1 1 NEMP family NEMP PF10225.9 KFM78866.1 - 8.5e-28 97.7 0.0 9.6e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 NEMP family FMO-like PF00743.19 KFM78867.1 - 2.8e-80 270.2 0.0 3.5e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like DUF624 PF04854.14 KFM78867.1 - 0.063 13.4 0.5 0.72 10.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF624 p31comet PF06581.12 KFM78867.1 - 0.13 11.4 0.1 0.46 9.6 0.0 1.7 2 0 0 2 2 2 0 Mad1 and Cdc20-bound-Mad2 binding Utp21 PF04192.12 KFM78869.1 - 1.7e-53 181.5 1.3 2.8e-53 180.8 1.3 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KFM78869.1 - 2.1e-06 28.4 0.5 0.00035 21.3 0.1 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM78869.1 - 0.0006 20.1 0.0 0.007 16.6 0.0 2.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain AATase PF07247.12 KFM78870.1 - 0.025 13.2 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase CRAL_TRIO_N PF03765.15 KFM78870.1 - 0.083 13.1 0.7 0.24 11.6 0.7 1.8 1 1 0 1 1 1 0 CRAL/TRIO, N-terminal domain Phage_G PF02306.15 KFM78870.1 - 0.083 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Major spike protein (G protein) RTP1_C1 PF10363.9 KFM78870.1 - 0.15 12.2 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 MULE PF10551.9 KFM78872.1 - 0.00015 22.1 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 MULE transposase domain RNase_H PF00075.24 KFM78874.1 - 4.4e-07 30.2 0.8 7.6e-07 29.4 0.1 1.8 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 KFM78874.1 - 1.3e-06 28.2 0.1 2.7e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase-like BTB PF00651.31 KFM78875.1 - 8.6e-24 83.9 0.1 5.8e-23 81.2 0.0 2.3 3 1 0 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFM78875.1 - 6e-08 32.7 1.3 7.5e-06 26.0 0.7 2.3 2 0 0 2 2 2 2 BTB And C-terminal Kelch Fringe PF02434.16 KFM78876.1 - 1.5e-09 37.7 0.5 2.5e-09 36.9 0.5 1.4 1 0 0 1 1 1 1 Fringe-like Ste5 PF11610.8 KFM78877.1 - 0.022 14.6 1.4 0.025 14.4 0.0 1.8 2 0 0 2 2 2 0 Scaffold protein Ste5, Fus3-binding region zf-FCS PF06467.14 KFM78878.1 - 0.0043 17.0 6.3 0.072 13.0 1.2 2.5 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.6 KFM78878.1 - 0.027 15.3 8.3 0.62 11.0 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM78878.1 - 0.085 13.3 7.4 2.3 8.9 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type VATC PF18716.1 KFM78878.1 - 0.13 12.2 4.6 25 4.8 0.2 3.4 3 0 0 3 3 3 0 Vms1-associating treble clef domain PyrI_C PF02748.15 KFM78878.1 - 0.45 10.5 5.4 1.2 9.1 0.2 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ran_BP1 PF00638.18 KFM78879.1 - 2.6e-14 53.5 0.1 5.8e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain GATA PF00320.27 KFM78880.1 - 1e-14 53.8 2.3 1e-14 53.8 2.3 2.2 2 0 0 2 2 2 1 GATA zinc finger Auto_anti-p27 PF06677.12 KFM78880.1 - 0.026 14.7 0.3 0.078 13.2 0.3 1.8 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-CCCH_7 PF18586.1 KFM78880.1 - 0.54 10.6 4.1 1.5 9.2 0.0 3.2 2 1 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 DUF3039 PF11238.8 KFM78880.1 - 1 9.2 8.4 1.7 8.4 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) DZR PF12773.7 KFM78880.1 - 3.5 7.7 11.1 38 4.4 3.1 2.6 1 1 1 2 2 2 0 Double zinc ribbon VEFS-Box PF09733.9 KFM78883.1 - 7.9e-56 187.7 0.0 1.1e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 VEFS-Box of polycomb protein AAA_19 PF13245.6 KFM78883.1 - 0.049 14.0 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 KFM78884.1 - 1.3e-07 31.4 0.1 1.3e-07 31.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.27 KFM78885.1 - 1.3e-40 137.2 0.6 1.8e-21 75.9 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein ThrE_2 PF12821.7 KFM78885.1 - 1.3 9.1 3.7 8 6.6 0.1 2.6 2 1 0 3 3 3 0 Threonine/Serine exporter, ThrE Tcell_CD4_C PF12104.8 KFM78886.1 - 0.26 11.2 0.2 0.41 10.6 0.2 1.2 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region ECSCR PF15820.5 KFM78887.1 - 0.34 10.8 2.0 0.38 10.6 2.0 1.1 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Sugar_tr PF00083.24 KFM78888.1 - 4.4e-55 187.3 0.4 4.9e-55 187.2 0.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM78888.1 - 2.2e-11 43.3 0.1 2.8e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM78889.1 - 3.5e-07 29.4 1.1 4.2e-07 29.2 1.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM78889.1 - 0.00067 18.7 0.8 0.00084 18.4 0.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ECF-ribofla_trS PF07155.12 KFM78889.1 - 0.018 15.1 1.5 0.025 14.6 1.5 1.2 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component 5TM-5TMR_LYT PF07694.12 KFM78889.1 - 0.09 12.3 3.8 0.11 12.0 3.8 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF5634_N PF18672.1 KFM78889.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5634) CPP1-like PF11833.8 KFM78889.1 - 0.15 11.7 0.8 0.18 11.5 0.8 1.0 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF4504 PF14953.6 KFM78890.1 - 1.4e-27 96.8 0.2 1.7e-27 96.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) Iwr1 PF08574.10 KFM78893.1 - 4.9e-08 33.9 19.1 4.9e-08 33.9 19.1 3.6 2 2 1 3 3 3 1 Transcription factor Iwr1 MAGSP PF03082.14 KFM78893.1 - 0.004 16.8 0.6 0.004 16.8 0.6 1.7 1 1 1 2 2 2 1 Male accessory gland secretory protein DUF229 PF02995.17 KFM78895.1 - 6e-135 450.6 0.0 7.5e-135 450.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 KFM78895.1 - 0.00067 19.1 0.1 0.014 14.8 0.0 2.0 1 1 1 2 2 2 1 Sulfatase MmlI PF09448.10 KFM78895.1 - 0.0069 16.8 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase IgaA PF07095.11 KFM78895.1 - 0.057 11.4 0.0 0.083 10.9 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Phosphodiest PF01663.22 KFM78895.1 - 0.059 12.9 0.0 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFM78896.1 - 1.9e-123 412.7 0.2 1.9e-123 412.7 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 KFM78896.1 - 5.3e-08 32.6 0.2 1.4e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 Sulfatase Phosphodiest PF01663.22 KFM78896.1 - 0.045 13.3 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Exo_endo_phos PF03372.23 KFM78897.1 - 5.3e-23 81.7 0.1 8.9e-23 81.0 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFM78897.1 - 0.048 13.5 0.0 0.16 11.8 0.0 1.9 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF4825 PF16107.5 KFM78898.1 - 0.18 11.9 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4825) fn3 PF00041.21 KFM78901.1 - 5.5e-35 119.6 2.1 2e-14 53.7 0.1 3.4 3 0 0 3 3 3 3 Fibronectin type III domain fn3_2 PF16893.5 KFM78901.1 - 0.00081 19.5 0.0 0.0027 17.8 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain DAG1 PF05454.11 KFM78901.1 - 0.025 14.0 0.2 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Insulin_TMD PF17870.1 KFM78901.1 - 0.13 12.4 1.8 0.25 11.4 1.8 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pur_ac_phosph_N PF16656.5 KFM78901.1 - 0.4 11.3 4.2 9 7.0 0.1 3.6 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain I-set PF07679.16 KFM78902.1 - 4.6e-09 36.2 0.0 6.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM78902.1 - 2e-07 31.5 0.0 4.7e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain fn3 PF00041.21 KFM78902.1 - 1.7e-06 28.3 0.0 3.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain V-set PF07686.17 KFM78902.1 - 0.00014 22.0 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM78902.1 - 0.00052 20.3 0.0 0.00087 19.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM78902.1 - 0.001 19.2 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFM78902.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFM78903.1 - 2.6e-16 60.0 0.0 8.3e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM78903.1 - 1e-11 44.7 0.0 1.5e-08 34.6 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM78903.1 - 1.6e-10 41.2 0.0 2.4e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM78903.1 - 5.6e-08 32.8 0.0 5.3e-05 23.3 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM78903.1 - 7e-06 26.2 0.2 0.0057 16.8 0.0 2.9 2 1 1 3 3 3 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM78903.1 - 6.9e-05 22.3 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM78903.1 - 0.006 16.6 0.1 0.031 14.3 0.0 2.2 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain NPCBM_assoc PF10633.9 KFM78903.1 - 0.025 14.8 0.2 0.044 14.0 0.1 1.6 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Peptidase_M16_C PF05193.21 KFM78903.1 - 0.14 12.1 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase M16 inactive domain V-set_CD47 PF08204.11 KFM78903.1 - 0.18 11.8 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain DUF3585 PF12130.8 KFM78905.1 - 7.9e-37 126.4 24.7 7.9e-37 126.4 24.7 2.4 3 0 0 3 3 3 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 KFM78905.1 - 2.6e-24 85.5 0.0 3.5e-23 81.9 0.0 2.7 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM78905.1 - 3.3e-06 26.8 0.0 1.2e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 CAMSAP CH domain 7tm_2 PF00002.24 KFM78907.1 - 2.3e-12 46.8 0.2 2.7e-12 46.5 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) fn3 PF00041.21 KFM78908.1 - 6.5e-12 45.6 0.5 3.6e-07 30.4 0.2 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM78908.1 - 2.2e-08 34.5 1.2 0.0051 17.4 0.3 2.4 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Lectin_C PF00059.21 KFM78908.1 - 7.1e-05 23.5 4.9 7.1e-05 23.5 4.9 1.7 2 0 0 2 2 2 1 Lectin C-type domain Interfer-bind PF09294.10 KFM78908.1 - 0.011 16.0 0.0 7.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Cul7 PF11515.8 KFM78908.1 - 0.029 14.7 0.1 1 9.7 0.0 2.7 3 0 0 3 3 3 0 Mouse development and cellular proliferation protein Cullin-7 DUF4493 PF14900.6 KFM78908.1 - 0.031 14.1 1.9 0.3 10.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4493) DUF3221 PF11518.8 KFM78908.1 - 0.097 13.0 0.2 0.47 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) PhoD_N PF16655.5 KFM78908.1 - 0.18 12.4 0.7 12 6.6 0.0 2.7 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Uroplakin_II PF07353.12 KFM78908.1 - 0.23 11.0 0.3 1.7 8.1 0.1 2.0 2 0 0 2 2 2 0 Uroplakin II zf-H2C2_2 PF13465.6 KFM78909.1 - 1.2e-43 145.6 39.4 6.8e-09 35.8 0.1 9.2 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78909.1 - 2.3e-38 128.5 56.2 3.1e-05 24.2 1.3 9.1 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78909.1 - 6.1e-31 104.4 55.0 0.00017 22.2 1.2 9.0 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM78909.1 - 3.2e-18 65.5 51.3 0.027 14.9 2.8 9.1 9 0 0 9 9 9 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM78909.1 - 4.9e-17 61.7 42.1 0.0051 17.1 0.0 9.2 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM78909.1 - 1e-12 47.7 50.8 0.017 15.1 1.0 9.2 9 0 0 9 9 9 6 C2H2-type zinc finger zf-Di19 PF05605.12 KFM78909.1 - 4.2e-07 30.1 43.1 0.12 12.7 3.1 6.1 2 2 5 7 7 7 6 Drought induced 19 protein (Di19), zinc-binding Baculo_IE-1 PF05290.11 KFM78909.1 - 8e-05 22.6 24.7 0.0083 16.1 7.0 6.1 1 1 4 5 5 5 1 Baculovirus immediate-early protein (IE-0) zf_UBZ PF18439.1 KFM78909.1 - 0.00058 19.4 32.7 5.1 6.8 0.1 8.5 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger BolA PF01722.18 KFM78909.1 - 0.0014 18.8 8.5 2.2 8.6 0.3 5.2 1 1 3 5 5 5 1 BolA-like protein DZR PF12773.7 KFM78909.1 - 0.0022 18.0 26.4 0.062 13.3 0.5 5.0 3 1 0 3 3 3 2 Double zinc ribbon zf-FCS PF06467.14 KFM78909.1 - 0.0035 17.2 26.0 0.82 9.7 0.4 6.6 6 1 1 7 7 7 3 MYM-type Zinc finger with FCS sequence motif zf-H2C2_5 PF13909.6 KFM78909.1 - 0.0056 16.4 30.5 1.1 9.1 0.1 8.1 8 0 0 8 8 8 1 C2H2-type zinc-finger domain zf-MYST PF17772.1 KFM78909.1 - 0.008 15.8 33.0 1.1 8.9 0.2 7.7 3 2 5 8 8 8 3 MYST family zinc finger domain zf-C2H2_8 PF15909.5 KFM78909.1 - 0.0086 16.4 30.7 0.66 10.3 1.1 5.0 1 1 5 6 6 6 3 C2H2-type zinc ribbon C1_4 PF07975.12 KFM78909.1 - 0.014 15.7 40.4 0.45 10.8 1.1 5.7 2 2 4 6 6 6 0 TFIIH C1-like domain K_oxygenase PF13434.6 KFM78909.1 - 0.12 11.5 0.1 1 8.4 0.0 2.1 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Zf_RING PF16744.5 KFM78909.1 - 0.22 11.7 33.8 0.77 9.9 0.2 7.7 1 1 6 8 8 8 0 KIAA1045 RING finger GAGA PF09237.11 KFM78909.1 - 0.22 11.3 19.5 2.2 8.2 0.8 6.2 2 2 5 7 7 7 0 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM78909.1 - 0.24 11.5 22.4 1.6 8.9 0.0 7.6 9 0 0 9 9 9 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 KFM78909.1 - 0.36 11.2 43.4 3.7 7.9 0.3 7.8 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM78909.1 - 0.39 11.5 29.2 4.5 8.1 0.9 4.8 1 1 2 4 4 4 0 zinc-ribbon family FYVE PF01363.21 KFM78909.1 - 0.51 10.5 40.0 3.1 8.0 1.5 5.3 1 1 3 4 4 4 0 FYVE zinc finger Prok-RING_1 PF14446.6 KFM78909.1 - 0.58 10.1 34.0 12 5.9 0.1 8.5 8 1 0 8 8 8 0 Prokaryotic RING finger family 1 DUF2256 PF10013.9 KFM78909.1 - 0.6 10.3 31.4 6.2 7.0 0.1 8.5 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) U71 PF17474.2 KFM78909.1 - 0.62 10.0 0.1 0.62 10.0 0.1 4.0 5 0 0 5 5 3 0 Tegument protein UL11 homolog zf_C2H2_ZHX PF18387.1 KFM78909.1 - 0.79 9.4 26.3 0.48 10.1 1.8 5.9 1 1 6 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-RRPl_C4 PF17026.5 KFM78909.1 - 1.4 9.1 29.2 7.9 6.6 5.0 3.8 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2HC_2 PF13913.6 KFM78909.1 - 2 8.4 0.0 2 8.4 0.0 7.5 9 0 0 9 9 9 0 zinc-finger of a C2HC-type PHD PF00628.29 KFM78909.1 - 4.4 7.3 37.3 1.5 8.7 0.9 6.5 3 2 3 6 6 6 0 PHD-finger ThiF PF00899.21 KFM78910.1 - 4.6e-35 121.1 0.0 7.4e-35 120.5 0.0 1.3 1 1 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KFM78910.1 - 0.0033 17.5 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1659 PF07872.11 KFM78910.1 - 0.13 11.9 0.0 0.5 10.1 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1659) TrkA_N PF02254.18 KFM78910.1 - 0.14 12.4 0.6 1.2 9.5 0.2 2.2 1 1 0 2 2 2 0 TrkA-N domain GOLD_2 PF13897.6 KFM78911.1 - 5.6e-69 230.9 0.9 5.6e-69 230.9 0.9 3.0 3 0 0 3 3 3 1 Golgi-dynamics membrane-trafficking ACBP PF00887.19 KFM78911.1 - 5.3e-13 49.0 0.0 1.3e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein AP1AR PF15745.5 KFM78911.1 - 2.4e-06 27.4 8.8 3.7e-06 26.8 8.8 1.3 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein DUF3527 PF12043.8 KFM78911.1 - 0.6 9.6 11.2 1.3 8.5 11.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) U79_P34 PF03064.16 KFM78911.1 - 0.75 9.1 10.4 1.4 8.2 10.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4304 PF14137.6 KFM78911.1 - 2.4 8.4 7.7 8.8 6.5 5.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4304) DUF4192 PF13830.6 KFM78911.1 - 3.8 7.5 5.2 6.9 6.6 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Androgen_recep PF02166.16 KFM78911.1 - 9 5.0 7.8 14 4.3 7.8 1.3 1 0 0 1 1 1 0 Androgen receptor Tcp11 PF05794.13 KFM78912.1 - 2.1e-89 300.6 7.3 2.5e-89 300.4 7.3 1.0 1 0 0 1 1 1 1 T-complex protein 11 Phage_Treg PF04761.12 KFM78912.1 - 0.092 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator TPR_19 PF14559.6 KFM78913.1 - 1.3e-07 32.0 0.0 1.1 9.9 0.0 4.0 2 1 1 4 4 4 2 Tetratricopeptide repeat Suf PF05843.14 KFM78913.1 - 1.9e-06 28.1 3.5 0.0026 17.8 0.4 2.1 1 1 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KFM78913.1 - 0.00043 20.9 0.0 7.5 7.7 0.0 4.3 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM78913.1 - 0.0013 18.0 0.7 0.0093 15.2 0.6 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 KFM78913.1 - 0.0025 17.5 1.6 0.15 11.7 0.0 2.9 1 1 2 3 3 3 1 26S proteasome subunit RPN7 TPR_16 PF13432.6 KFM78913.1 - 0.0028 18.3 0.0 0.059 14.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Ribosomal_S7 PF00177.21 KFM78913.1 - 0.0034 17.0 0.3 0.17 11.5 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e TPR_6 PF13174.6 KFM78913.1 - 0.0051 17.4 1.6 18 6.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM78913.1 - 0.01 15.9 0.5 10 6.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat motB PF17613.2 KFM78913.1 - 0.014 15.3 0.3 0.026 14.4 0.3 1.6 1 1 0 1 1 1 0 Modifier of transcription NRDE-2 PF08424.10 KFM78913.1 - 0.016 14.3 2.9 0.2 10.7 0.2 2.5 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference PPR PF01535.20 KFM78913.1 - 0.034 14.4 0.1 7.9 7.0 0.0 2.7 2 0 0 2 2 2 0 PPR repeat RNA_pol_Rpb6 PF01192.22 KFM78913.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb6 PPR_2 PF13041.6 KFM78913.1 - 0.21 11.8 2.9 5.1 7.4 0.0 3.6 4 0 0 4 4 4 0 PPR repeat family DUF1647 PF07801.11 KFM78916.1 - 2.7e-12 46.7 1.6 8.9e-12 44.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1647) CLLAC PF15675.5 KFM78916.1 - 0.55 9.8 6.8 1.2 8.8 6.8 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain BIR PF00653.21 KFM78917.1 - 2e-60 201.3 11.3 3e-20 72.6 1.3 3.9 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 KFM78917.1 - 4.8e-07 29.5 3.5 4.8e-07 29.5 3.5 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC PF07967.13 KFM78917.1 - 1.1e-06 28.7 2.9 0.35 10.9 0.4 3.7 2 1 0 3 3 3 3 C3HC zinc finger-like Prok-RING_4 PF14447.6 KFM78917.1 - 0.32 10.9 10.8 0.17 11.8 5.4 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF1644 PF07800.12 KFM78917.1 - 2.3 8.2 12.5 3.9 7.5 0.0 4.7 2 1 3 5 5 5 0 Protein of unknown function (DUF1644) zinc_ribbon_9 PF14369.6 KFM78917.1 - 5.9 7.2 9.2 48 4.3 0.1 4.4 4 0 0 4 4 4 0 zinc-ribbon CCDC50_N PF15295.6 KFM78920.1 - 2.9e-33 114.7 49.8 2.1e-30 105.5 20.9 2.8 2 2 0 2 2 2 2 Coiled-coil domain-containing protein 50 N-terminus TMCCDC2 PF15844.5 KFM78920.1 - 0.44 10.5 3.7 0.9 9.4 3.7 1.5 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Ribosomal_L3 PF00297.22 KFM78921.1 - 2.5e-186 619.0 15.6 2.9e-186 618.8 15.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RTX PF02382.15 KFM78921.1 - 0.045 13.4 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein Cupin_8 PF13621.6 KFM78922.1 - 1.3e-07 31.6 0.9 6.2e-07 29.4 0.8 1.9 1 1 0 1 1 1 1 Cupin-like domain EF-hand_5 PF13202.6 KFM78922.1 - 3e-05 23.3 0.4 0.003 17.0 0.5 3.3 2 1 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KFM78922.1 - 4.3e-05 22.8 1.2 0.0023 17.3 0.3 3.6 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 KFM78922.1 - 0.00028 20.6 0.8 0.027 14.4 0.2 3.8 3 1 1 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 KFM78922.1 - 0.0076 16.1 0.3 0.15 12.0 0.2 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KFM78922.1 - 0.12 12.9 2.9 0.46 11.0 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain pair DUSP PF06337.12 KFM78922.1 - 3.2 8.4 6.1 7.2 7.3 2.7 2.7 2 1 0 2 2 2 0 DUSP domain AIRS_C PF02769.22 KFM78923.1 - 2.1e-28 99.4 0.1 4.2e-28 98.4 0.1 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KFM78923.1 - 1.1e-10 42.0 0.9 2.2e-10 41.1 0.2 1.8 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain TPK_B1_binding PF04265.14 KFM78923.1 - 0.046 13.4 0.1 1.9 8.2 0.1 2.9 2 1 0 2 2 2 0 Thiamin pyrophosphokinase, vitamin B1 binding domain zf-UDP PF14569.6 KFM78924.1 - 0.024 14.8 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger TAF8_C PF10406.9 KFM78925.1 - 1.3e-20 73.7 5.0 2.8e-20 72.6 5.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Pilt PF15453.6 KFM78926.1 - 0.064 12.7 10.1 0.072 12.5 10.1 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Hid1 PF12722.7 KFM78926.1 - 5.5 5.0 9.3 6.2 4.8 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HCNGP PF07818.13 KFM78927.1 - 2.1e-25 89.2 0.2 3.1e-25 88.6 0.2 1.3 1 0 0 1 1 1 1 HCNGP-like protein IPP-2 PF04979.14 KFM78928.1 - 1.2e-34 120.0 10.8 1.4e-34 119.7 10.8 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) FAM176 PF14851.6 KFM78928.1 - 0.1 12.2 2.4 0.15 11.7 2.4 1.4 1 0 0 1 1 1 0 FAM176 family Helicase_RecD PF05127.14 KFM78930.1 - 0.069 13.0 0.1 0.11 12.3 0.1 1.3 1 1 0 1 1 1 0 Helicase Trypsin PF00089.26 KFM78932.1 - 8.8e-33 114.0 1.3 9.6e-33 113.8 1.3 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_S6 PF02395.16 KFM78932.1 - 0.047 11.7 0.0 0.057 11.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease CLIP PF12032.8 KFM78933.1 - 0.00064 19.9 1.3 0.11 12.8 1.6 2.7 2 1 0 2 2 2 2 Regulatory CLIP domain of proteinases Clat_adaptor_s PF01217.20 KFM78934.1 - 5.3e-48 162.6 2.6 6.3e-48 162.3 2.6 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Neur_chan_LBD PF02931.23 KFM78936.1 - 6.9e-33 113.9 1.5 9.3e-33 113.5 1.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM78936.1 - 5.4e-24 85.6 15.0 6.2e-20 72.3 13.2 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region ZYG-11_interact PF05884.12 KFM78936.1 - 0.14 11.6 1.9 0.22 10.9 1.9 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Neur_chan_LBD PF02931.23 KFM78937.1 - 4e-36 124.5 1.4 9.4e-36 123.3 1.5 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM78937.1 - 1.4e-25 90.8 18.0 2.7e-25 89.8 2.0 3.3 3 0 0 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region Lipase_GDSL_2 PF13472.6 KFM78937.1 - 4.6e-05 23.9 0.0 8.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFM78937.1 - 0.0051 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SR-25 PF10500.9 KFM78940.1 - 0.03 13.9 6.0 0.035 13.7 6.0 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 KFM78941.1 - 3.7e-56 190.4 0.0 4.2e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM78941.1 - 3.8e-32 111.6 0.0 4.6e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFM78941.1 - 1.3e-09 38.6 0.5 2.2e-09 37.8 0.5 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KFM78941.1 - 0.00055 19.9 0.1 0.0041 17.1 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFM78941.1 - 0.0017 17.3 0.0 0.0024 16.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM78941.1 - 0.0058 16.0 0.0 0.0083 15.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM78941.1 - 0.0063 15.9 0.1 0.015 14.7 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM78941.1 - 0.064 12.0 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KFM78941.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 KFM78941.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 NUDIX PF00293.28 KFM78942.1 - 3.3e-12 46.6 0.0 5.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain HTH_Tnp_Tc5 PF03221.16 KFM78943.1 - 0.00069 19.6 0.1 0.001 19.0 0.1 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.8 KFM78943.1 - 0.032 14.3 0.3 0.072 13.2 0.2 1.8 1 1 0 1 1 1 0 Stage III sporulation protein D RSN1_TM PF13967.6 KFM78945.1 - 0.086 12.6 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport T2SSM PF04612.12 KFM78945.1 - 0.12 12.5 0.1 0.26 11.3 0.0 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Peptidase_M3_N PF08439.10 KFM78946.1 - 0.0053 17.0 0.1 0.0091 16.2 0.1 1.3 1 0 0 1 1 1 1 Oligopeptidase F TPT PF03151.16 KFM78947.1 - 2.4e-74 250.3 13.8 2.9e-74 250.0 13.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM78947.1 - 3.9e-09 36.8 19.6 3.9e-05 23.8 8.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFM78947.1 - 8.6e-08 31.7 14.7 2.3e-07 30.3 14.7 1.6 1 1 0 1 1 1 1 UAA transporter family DUF680 PF05079.12 KFM78947.1 - 0.096 13.4 0.1 0.19 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF680) AdoMet_MTase PF07757.13 KFM78949.1 - 5.9e-20 71.7 0.1 2.2e-19 69.8 0.0 2.0 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KFM78949.1 - 0.0015 18.5 1.4 0.0067 16.4 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM78949.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFM78949.1 - 0.015 14.9 0.1 0.062 12.9 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DOT1 PF08123.13 KFM78949.1 - 0.026 14.1 0.0 0.079 12.5 0.0 1.8 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KFM78949.1 - 0.037 13.8 0.0 0.094 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFM78949.1 - 0.067 13.9 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFM78949.1 - 0.087 13.5 0.1 0.25 12.1 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KFM78949.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain zf-H2C2_2 PF13465.6 KFM78950.1 - 1.6e-18 66.2 85.3 2.4e-05 24.5 5.6 10.8 10 0 0 10 10 10 7 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM78950.1 - 5.2e-11 42.1 93.8 2.2e-05 24.1 9.0 9.6 9 0 0 9 9 9 7 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM78950.1 - 4.1e-09 36.4 107.6 0.00041 20.7 1.2 10.0 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78950.1 - 0.00059 20.4 7.4 0.0096 16.7 0.8 10.4 10 0 0 10 10 10 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM78950.1 - 0.0079 15.9 0.0 0.0079 15.9 0.0 4.8 5 0 0 5 5 5 1 zinc-finger C2H2-type zf-C2H2_7 PF15269.6 KFM78950.1 - 0.015 15.3 1.9 0.015 15.3 1.9 7.3 3 2 6 9 9 9 0 Zinc-finger Zn_Tnp_IS1595 PF12760.7 KFM78950.1 - 0.032 14.2 1.1 0.032 14.2 1.1 5.3 4 2 1 5 5 5 0 Transposase zinc-ribbon domain Scramblase PF03803.15 KFM78950.1 - 0.099 11.9 0.8 0.25 10.6 0.6 1.7 1 1 0 1 1 1 0 Scramblase zf-met PF12874.7 KFM78950.1 - 0.11 13.0 0.5 0.11 13.0 0.5 8.1 8 0 0 8 8 8 0 Zinc-finger of C2H2 type BTB PF00651.31 KFM78951.1 - 4.7e-14 52.6 0.1 5.8e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain zf-C2HC PF01530.18 KFM78951.1 - 0.069 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C2HC type DUF1751 PF08551.10 KFM78951.1 - 0.14 12.7 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) RabGAP-TBC PF00566.18 KFM78952.1 - 2.7e-43 148.2 1.9 2.7e-43 148.2 1.9 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TNFR_c6 PF00020.18 KFM78954.1 - 3.2e-16 59.4 20.4 2.5e-10 40.6 8.5 2.7 2 0 0 2 2 2 2 TNFR/NGFR cysteine-rich region Adeno_E3_CR2 PF02439.15 KFM78954.1 - 0.03 14.1 2.8 0.058 13.2 2.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2730 PF10805.8 KFM78954.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) EphA2_TM PF14575.6 KFM78954.1 - 1.1 10.2 2.9 3.2 8.7 0.4 2.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 KFM78954.1 - 3.8 7.4 6.0 0.16 11.9 0.4 1.5 2 0 0 2 2 2 0 Protocadherin UQ_con PF00179.26 KFM78955.1 - 2e-37 128.0 0.0 2.6e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RRM_1 PF00076.22 KFM78956.1 - 3.2e-14 52.5 0.0 5e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OST_P2 PF18235.1 KFM78956.1 - 0.031 14.2 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase Peripheral 2 domain UQ_con PF00179.26 KFM78957.1 - 2.9e-47 159.8 0.0 3.3e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM78957.1 - 1.6e-05 24.6 0.0 2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B CD20 PF04103.15 KFM78958.1 - 2.6e-07 30.9 14.9 3.6e-07 30.4 12.1 2.0 2 0 0 2 2 2 1 CD20-like family BCLP PF12304.8 KFM78958.1 - 0.088 12.4 9.3 0.021 14.4 3.8 2.1 2 0 0 2 2 2 0 Beta-casein like protein DUF4131 PF13567.6 KFM78958.1 - 0.57 9.8 2.5 0.66 9.6 1.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Hormone_3 PF00159.18 KFM78961.1 - 1.4e-10 41.0 0.1 2.5e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Pancreatic hormone peptide DUF4696 PF15767.5 KFM78961.1 - 0.08 11.5 0.0 0.1 11.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4696) Snf7 PF03357.21 KFM78962.1 - 1.8e-52 177.5 18.4 2e-52 177.2 18.4 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.20 KFM78962.1 - 0.0096 15.9 0.8 0.0096 15.9 0.8 3.3 1 1 2 3 3 3 1 Prefoldin subunit DUF150 PF02576.17 KFM78962.1 - 0.034 14.6 0.1 0.081 13.3 0.1 1.7 1 0 0 1 1 1 0 RimP N-terminal domain NPV_P10 PF05531.12 KFM78962.1 - 0.054 14.0 5.3 1.7 9.2 2.2 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FliJ PF02050.16 KFM78962.1 - 0.2 11.9 14.9 0.12 12.6 5.5 3.0 1 1 2 3 3 3 0 Flagellar FliJ protein DUF948 PF06103.11 KFM78962.1 - 0.41 10.9 2.8 1.1 9.5 0.4 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1319 PF07028.11 KFM78962.1 - 0.41 10.9 5.5 0.21 11.8 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Hydantoinase_B PF02538.14 KFM78962.1 - 0.45 8.9 2.1 0.56 8.6 2.1 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Uso1_p115_C PF04871.13 KFM78962.1 - 0.87 10.0 22.4 2 8.8 14.5 2.9 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YlqD PF11068.8 KFM78962.1 - 1.1 9.7 16.1 3.1 8.2 3.3 2.1 1 1 1 2 2 2 0 YlqD protein Glutaredoxin PF00462.24 KFM78962.1 - 1.4 9.2 6.2 1.5 9.1 0.6 3.0 2 1 1 3 3 3 0 Glutaredoxin FlxA PF14282.6 KFM78962.1 - 2.7 8.0 15.8 1.6 8.7 10.9 2.3 1 1 2 3 3 3 0 FlxA-like protein Spore_III_AB PF09548.10 KFM78962.1 - 3.7 7.6 8.4 5.8 7.0 5.2 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) FapA PF03961.13 KFM78962.1 - 6.2 5.3 14.0 11 4.5 11.0 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A PEP-utilisers_N PF05524.13 KFM78962.1 - 6.5 7.0 8.1 1.6 8.9 2.2 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal FCP1_C PF09309.10 KFM78963.1 - 0.0012 18.8 34.6 0.013 15.4 0.2 4.3 2 1 1 4 4 4 3 FCP1, C-terminal PTCB-BRCT PF12738.7 KFM78963.1 - 0.0013 18.7 0.1 0.0028 17.6 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_3 PF18428.1 KFM78963.1 - 0.22 11.6 0.7 0.55 10.3 0.7 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFM78963.1 - 1.4 9.3 3.7 1.4 9.3 0.2 2.4 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Ndc1_Nup PF09531.10 KFM78963.1 - 8.8 4.9 6.3 0.84 8.3 1.8 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Biotin_lipoyl PF00364.22 KFM78964.1 - 0.002 17.9 0.0 0.0057 16.5 0.0 1.7 1 1 0 1 1 1 1 Biotin-requiring enzyme HlyD_D23 PF16576.5 KFM78964.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KFM78964.1 - 0.15 12.7 0.0 0.33 11.7 0.0 1.5 1 0 0 1 1 1 0 HlyD family secretion protein zf-H2C2_2 PF13465.6 KFM78965.1 - 9.8e-13 47.9 15.1 1.9e-06 28.0 2.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM78965.1 - 1.2e-09 38.1 9.6 2.6e-06 27.6 2.0 2.7 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM78965.1 - 5.6e-07 29.9 8.4 0.005 17.6 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM78965.1 - 7.2e-07 29.1 6.2 0.0073 16.3 2.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM78965.1 - 0.00021 21.5 0.6 0.5 10.7 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM78965.1 - 0.0076 16.0 9.9 0.072 12.9 0.4 2.9 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFM78965.1 - 0.011 16.4 3.9 0.039 14.6 1.4 1.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Prok-RING_1 PF14446.6 KFM78965.1 - 0.016 15.2 0.2 3.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RNA_pol_N PF01194.17 KFM78965.1 - 0.018 15.3 0.1 0.44 10.9 0.0 2.2 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit zf-C2H2_2 PF12756.7 KFM78965.1 - 0.019 15.3 4.2 0.54 10.6 0.5 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM78965.1 - 0.03 14.5 1.9 5.8 7.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) XPA_N PF01286.18 KFM78965.1 - 0.045 13.8 1.4 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zf-BED PF02892.15 KFM78965.1 - 0.046 13.8 6.1 0.058 13.4 2.7 2.2 2 0 0 2 2 2 0 BED zinc finger zf-UBP PF02148.19 KFM78965.1 - 0.092 13.1 3.3 2.5 8.5 0.3 2.2 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein NADH-G_4Fe-4S_3 PF10588.9 KFM78965.1 - 0.099 12.2 0.4 3.9 7.1 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region GAGA PF09237.11 KFM78965.1 - 0.1 12.4 2.2 2.5 8.0 0.0 2.2 1 1 1 2 2 2 0 GAGA factor zf-LYAR PF08790.11 KFM78965.1 - 0.12 12.3 1.5 6.8 6.7 0.1 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF2072 PF09845.9 KFM78965.1 - 0.24 11.7 1.8 0.44 10.8 1.8 1.5 1 1 0 1 1 1 0 Zn-ribbon containing protein zf-met PF12874.7 KFM78965.1 - 0.29 11.6 3.4 16 6.1 1.9 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFM78965.1 - 0.32 11.5 4.7 3.4 8.2 0.4 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger CitX PF03802.14 KFM78965.1 - 0.48 10.2 3.4 6.4 6.5 0.4 2.0 1 1 1 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase zf_ZIC PF18366.1 KFM78965.1 - 0.58 10.3 4.0 2.2 8.5 0.5 2.7 2 1 1 3 3 3 0 Zic proteins zinc finger domain FYVE PF01363.21 KFM78965.1 - 2.4 8.4 6.8 18 5.6 6.8 2.0 1 1 0 1 1 1 0 FYVE zinc finger 7tm_1 PF00001.21 KFM78969.1 - 2.7e-56 190.8 20.4 3.7e-56 190.4 20.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM78969.1 - 3.5e-11 43.0 17.8 5.9e-11 42.2 17.8 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFM78969.1 - 8.9e-05 21.9 13.9 0.0016 17.8 13.9 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFM78969.1 - 0.045 13.5 11.5 0.068 12.9 11.5 1.5 1 1 0 1 1 1 0 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFM78969.1 - 0.058 13.0 24.1 0.037 13.7 21.7 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF3671 PF12420.8 KFM78969.1 - 0.46 10.6 3.6 4.4 7.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function CLZ PF16526.5 KFM78970.1 - 6.9e-23 80.8 6.5 1.6e-22 79.6 6.5 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 KFM78970.1 - 3.8e-20 71.7 0.0 6.6e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KFM78970.1 - 1.2e-15 57.5 10.0 1.6e-15 57.0 10.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFM78970.1 - 0.09 12.7 12.5 0.31 11.0 12.5 2.0 1 1 0 1 1 1 0 Ion channel SseC PF04888.12 KFM78970.1 - 0.098 12.2 0.2 0.43 10.1 0.2 1.8 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family EMC3_TMCO1 PF01956.16 KFM78970.1 - 2.3 8.0 6.7 0.76 9.5 0.1 2.6 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like OST3_OST6 PF04756.13 KFM78971.1 - 2.7e-108 361.8 0.5 3e-108 361.6 0.5 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF2339 PF10101.9 KFM78971.1 - 0.00039 19.2 1.5 0.00051 18.8 1.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF4131 PF13567.6 KFM78971.1 - 0.021 14.5 3.6 0.31 10.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Thioredoxin PF00085.20 KFM78971.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF4173 PF13777.6 KFM78971.1 - 0.29 10.5 5.1 0.78 9.1 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) FixQ PF05545.11 KFM78971.1 - 0.93 9.5 8.4 36 4.4 0.4 3.7 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF2909 PF11137.8 KFM78971.1 - 1.8 8.6 10.0 12 6.0 0.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2909) DUF2116 PF09889.9 KFM78971.1 - 9.4 6.3 6.4 6.9 6.7 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Xlink PF00193.17 KFM78972.1 - 0.037 14.4 0.0 0.045 14.1 0.0 1.2 1 0 0 1 1 1 0 Extracellular link domain PhoLip_ATPase_C PF16212.5 KFM78973.1 - 2e-77 260.4 25.5 2.6e-77 259.9 25.5 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 KFM78973.1 - 4.3e-09 36.3 0.0 8.5e-08 32.2 0.0 2.4 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFM78973.1 - 6.6e-08 33.1 0.0 5.2e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM78973.1 - 0.0022 17.8 0.3 0.0062 16.3 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase VPS28 PF03997.12 KFM78973.1 - 0.067 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 VPS28 protein DUF4392 PF14336.6 KFM78973.1 - 0.068 12.6 0.9 4.6 6.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) HAD PF12710.7 KFM78973.1 - 0.16 12.3 0.0 9.2 6.6 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Peptidase_C12 PF01088.21 KFM78974.1 - 8.7e-47 159.6 0.7 1e-46 159.4 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Herpes_IE2_3 PF03361.14 KFM78974.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 COesterase PF00135.28 KFM78975.1 - 1.9e-133 446.1 0.0 2.1e-133 445.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM78975.1 - 0.0013 18.7 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFM78976.1 - 1.8e-124 416.4 0.0 2.1e-124 416.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFM78976.1 - 0.0087 15.9 0.0 0.028 14.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold LapA_dom PF06305.11 KFM78976.1 - 0.15 11.9 0.8 0.39 10.6 0.8 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PWWP PF00855.17 KFM78978.1 - 2.6e-16 59.8 0.5 3.8e-16 59.3 0.5 1.3 1 0 0 1 1 1 1 PWWP domain SNAPc19 PF15497.6 KFM78979.1 - 0.44 11.0 3.6 1.1 9.8 0.3 2.8 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Ig_3 PF13927.6 KFM78981.1 - 5.3e-06 26.9 0.0 5.7e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM78981.1 - 8e-06 25.8 0.0 8.6e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM78981.1 - 3.2e-05 24.2 0.0 3.6e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM78981.1 - 0.0049 17.0 0.0 0.0056 16.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFM78981.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain C1-set PF07654.15 KFM78981.1 - 0.065 13.6 0.1 0.076 13.4 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin C1-set domain I-set PF07679.16 KFM78982.1 - 1.2e-15 57.4 0.0 1.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM78982.1 - 7.5e-11 42.5 0.0 1e-10 42.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM78982.1 - 1.2e-08 35.1 0.0 2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM78982.1 - 1.1e-06 28.7 0.0 1.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM78982.1 - 0.0016 18.6 0.1 0.01 16.0 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM78982.1 - 0.004 16.7 0.0 0.004 16.7 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_5 PF16681.5 KFM78982.1 - 0.047 14.1 0.0 0.078 13.4 0.0 1.4 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set_CD47 PF08204.11 KFM78982.1 - 0.11 12.4 0.2 0.11 12.4 0.2 1.8 2 1 0 2 2 2 0 CD47 immunoglobulin-like domain I-set PF07679.16 KFM78983.1 - 1.9e-48 162.5 0.1 3.1e-15 56.0 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM78983.1 - 1.8e-39 134.2 0.3 4.6e-13 49.6 0.0 3.7 4 0 0 4 4 3 3 Immunoglobulin domain fn3 PF00041.21 KFM78983.1 - 1.7e-31 108.4 1.9 1.2e-16 60.8 0.5 2.6 2 0 0 2 2 2 2 Fibronectin type III domain ig PF00047.25 KFM78983.1 - 1.9e-30 104.9 0.4 9.9e-09 35.3 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM78983.1 - 4.8e-29 100.5 0.0 8.2e-09 35.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM78983.1 - 7.5e-20 71.1 3.6 3.3e-08 33.7 0.0 5.9 3 3 0 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM78983.1 - 6.1e-09 35.3 0.0 0.0044 16.6 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 KFM78983.1 - 1.7e-06 28.3 0.1 0.051 14.0 0.1 3.9 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.5 KFM78983.1 - 6.8e-06 26.6 5.8 0.0017 18.9 0.2 3.4 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM78983.1 - 4.1e-05 23.8 0.0 0.15 12.4 0.0 2.7 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III C1-set PF07654.15 KFM78983.1 - 5.4e-05 23.5 0.1 0.17 12.3 0.1 3.9 3 1 0 3 3 3 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFM78983.1 - 0.00011 22.1 1.2 0.57 10.3 0.1 3.5 3 1 1 4 4 4 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFM78983.1 - 0.0025 18.0 0.5 17 5.6 0.1 4.1 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 C2-set PF05790.15 KFM78983.1 - 0.003 17.7 0.2 4.6 7.5 0.0 3.8 3 1 0 3 3 3 1 Immunoglobulin C2-set domain Ig_C17orf99 PF17736.1 KFM78983.1 - 0.0034 17.4 0.1 1.2 9.3 0.0 3.8 3 1 1 4 4 4 1 C17orf99 Ig domain Ig_4 PF16680.5 KFM78983.1 - 0.0045 17.2 0.2 3.8 7.8 0.2 3.6 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 KFM78983.1 - 0.6 9.9 6.3 33 4.3 0.0 4.3 3 1 2 5 5 5 0 Adenovirus E3 region protein CR1 FixQ PF05545.11 KFM78985.1 - 0.01 15.8 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ LST1 PF05083.13 KFM78985.1 - 0.017 15.4 0.7 0.057 13.7 0.7 1.9 1 1 0 1 1 1 0 LST-1 protein EphA2_TM PF14575.6 KFM78985.1 - 0.13 13.2 0.2 0.28 12.1 0.1 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4321 PF14209.6 KFM78988.1 - 0.1 12.4 1.3 0.19 11.6 1.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4321) DDE_Tnp_1_7 PF13843.6 KFM78989.1 - 0.0075 15.6 0.1 0.0075 15.6 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 Tyr-DNA_phospho PF06087.12 KFM78989.1 - 0.038 12.9 0.0 0.039 12.9 0.0 1.0 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase Ribosomal_L11 PF00298.19 KFM78989.1 - 0.19 12.2 0.6 0.34 11.5 0.6 1.4 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain NinE PF05322.11 KFM78989.1 - 0.61 10.0 3.0 7 6.6 0.5 2.3 2 1 0 2 2 2 0 NINE Protein SRCR PF00530.18 KFM78990.1 - 4.8e-28 97.6 3.4 3e-14 53.3 1.0 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Beta_helix PF13229.6 KFM78990.1 - 3e-22 79.1 100.2 4.3e-07 29.9 24.8 9.4 6 3 3 9 9 9 9 Right handed beta helix region SRCR_2 PF15494.6 KFM78990.1 - 3.6e-11 43.5 0.7 0.00031 21.2 0.0 2.9 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFM78990.1 - 5.7e-05 23.6 0.4 0.061 13.9 0.0 3.1 3 0 0 3 3 3 2 Hepsin, SRCR domain Lectin_C PF00059.21 KFM78990.1 - 0.00027 21.7 0.6 0.18 12.5 0.1 3.2 1 1 1 2 2 2 2 Lectin C-type domain CUB PF00431.20 KFM78990.1 - 0.0024 18.2 0.0 4.2 7.7 0.0 2.8 2 0 0 2 2 2 2 CUB domain UL45 PF05473.12 KFM78990.1 - 0.0028 17.3 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like mit_SMPDase PF14724.6 KFM78991.1 - 1.7e-06 26.4 0.0 1.7e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase mit_SMPDase PF14724.6 KFM78992.1 - 1e-66 225.5 6.5 1.5e-64 218.3 3.7 2.9 1 1 1 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase Glyco_trans_2_3 PF13632.6 KFM78992.1 - 0.042 13.7 1.4 0.098 12.6 1.4 1.6 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DUF4118 PF13493.6 KFM78992.1 - 0.11 12.3 4.1 0.31 10.9 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) FA_desaturase PF00487.24 KFM78993.1 - 2.3e-25 89.9 8.9 2.3e-25 89.9 8.9 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KFM78993.1 - 1.2e-23 82.3 0.3 2.1e-23 81.5 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) HXXEE PF13787.6 KFM78993.1 - 2 9.3 6.7 10 6.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif Bin3 PF06859.12 KFM78994.1 - 1.9e-40 137.8 1.4 2.3e-40 137.6 0.0 1.8 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 KFM78994.1 - 1.2e-10 41.9 0.0 6.2e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KFM78994.1 - 6e-09 35.9 0.0 9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM78994.1 - 3.8e-08 33.3 0.0 2.1e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM78994.1 - 5.3e-08 33.4 0.0 1.4e-05 25.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM78994.1 - 1.6e-07 32.0 0.0 0.03 15.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 KFM78994.1 - 7.4e-05 22.3 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KFM78994.1 - 0.0001 21.9 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KFM78994.1 - 0.00052 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFM78994.1 - 0.00067 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KFM78994.1 - 0.00085 18.3 0.0 0.043 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KFM78994.1 - 0.0011 18.4 0.0 0.003 17.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 KFM78994.1 - 0.015 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.16 KFM78994.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_2 PF00891.18 KFM78994.1 - 0.018 14.3 0.0 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_15 PF09445.10 KFM78994.1 - 0.031 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF43 PF01861.16 KFM78994.1 - 0.17 11.1 1.1 0.41 9.8 0.0 1.9 1 1 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain V-SNARE_C PF12352.8 KFM78995.1 - 0.00035 20.8 15.0 0.001 19.3 5.4 2.8 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Sec34 PF04136.15 KFM78995.1 - 0.0053 16.6 0.1 0.0053 16.6 0.1 3.1 3 1 0 3 3 3 1 Sec34-like family DUF1722 PF08349.11 KFM78995.1 - 0.052 13.8 0.8 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF5089 PF17002.5 KFM78995.1 - 0.36 10.7 11.9 0.3 10.9 3.3 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF5089) DASH_Duo1 PF08651.10 KFM78995.1 - 0.44 10.4 7.0 0.34 10.7 1.4 2.7 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF16 PF01519.16 KFM78995.1 - 3.6 8.1 11.1 5.4 7.5 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 Aldedh PF00171.22 KFM78996.1 - 7.2e-98 328.1 0.0 9.1e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 KFM78997.1 - 9.8e-69 231.6 0.1 1.4e-68 231.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 KFM78997.1 - 3.1e-41 139.4 1.2 8.1e-22 77.2 0.3 2.7 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 KFM78997.1 - 2.6e-38 131.8 0.1 4.2e-38 131.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM78997.1 - 8.3e-06 25.3 0.0 0.00028 20.3 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFM78997.1 - 0.00015 20.7 0.0 0.00025 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM78997.1 - 0.0072 15.3 0.6 0.013 14.4 0.6 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM78997.1 - 0.009 15.4 1.3 0.37 10.1 0.2 2.9 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Endopep_inhib PF16800.5 KFM78997.1 - 0.1 12.5 1.1 0.35 10.8 0.4 2.2 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor Ist1 PF03398.14 KFM78998.1 - 4.2e-64 215.4 4.5 5e-64 215.2 4.5 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DDE_Tnp_4 PF13359.6 KFM78999.1 - 2.1e-13 50.3 0.0 2.4e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM78999.1 - 0.12 11.9 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 Plant transposon protein TB2_DP1_HVA22 PF03134.19 KFM79002.1 - 3.5e-23 81.3 6.1 3.5e-23 81.3 6.1 1.7 3 0 0 3 3 3 1 TB2/DP1, HVA22 family Peptidase_A17 PF05380.13 KFM79003.1 - 0.00073 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase PsbU PF06514.11 KFM79004.1 - 0.064 13.3 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) TB2_DP1_HVA22 PF03134.19 KFM79005.1 - 3.9e-28 97.2 8.5 5.5e-28 96.7 8.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.9 KFM79005.1 - 0.042 14.1 1.1 0.068 13.4 1.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) SEO_N PF14576.6 KFM79005.1 - 0.076 12.2 0.1 0.076 12.2 0.1 1.2 1 0 0 1 1 1 0 Sieve element occlusion N-terminus MHCassoc_trimer PF08831.10 KFM79005.1 - 0.088 12.8 0.3 0.16 12.0 0.3 1.4 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain DUF2304 PF10066.9 KFM79005.1 - 0.25 11.6 4.3 0.41 10.9 4.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) adh_short_C2 PF13561.6 KFM79006.1 - 6.6e-53 179.7 0.0 8.3e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM79006.1 - 3.5e-49 166.9 0.5 4.6e-49 166.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM79006.1 - 9.3e-10 38.7 0.1 1.3e-09 38.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM79006.1 - 1.1e-06 28.3 0.0 5.2e-05 22.8 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KFM79006.1 - 0.027 13.8 0.0 0.099 12.0 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KFM79006.1 - 0.028 13.5 0.1 0.041 13.0 0.1 1.3 1 1 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 KFM79006.1 - 0.069 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KFM79007.1 - 5.1e-55 186.6 0.0 6.2e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM79007.1 - 1.8e-52 177.7 0.6 2.4e-52 177.3 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM79007.1 - 2.6e-09 37.2 0.1 3.7e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM79007.1 - 6e-08 32.4 0.1 2.8e-06 27.0 0.1 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFM79007.1 - 2.7e-05 23.4 0.1 3.9e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFM79007.1 - 4.9e-05 23.3 0.0 6.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 KFM79007.1 - 0.014 14.8 0.2 0.068 12.5 0.0 2.2 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KFM79007.1 - 0.028 13.8 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asp_protease_2 PF13650.6 KFM79008.1 - 1.4e-06 28.8 0.0 1.7e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 KFM79008.1 - 4.4e-06 26.6 0.0 5.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 KFM79008.1 - 1.3e-05 25.7 0.0 1.6e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KFM79008.1 - 1.8e-05 24.5 0.0 2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease P-II PF00543.22 KFM79008.1 - 0.043 14.4 0.2 12 6.6 0.1 2.1 1 1 1 2 2 2 0 Nitrogen regulatory protein P-II zf-H2C2_2 PF13465.6 KFM79009.1 - 7.4e-16 57.8 11.5 7.6e-10 38.8 0.6 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79009.1 - 3.7e-12 46.0 10.7 3.3e-06 27.2 1.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79009.1 - 2.3e-10 40.4 10.2 7.3e-05 23.3 1.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM79009.1 - 1.1e-08 35.2 7.5 0.00033 20.9 0.4 2.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM79009.1 - 3.3e-06 27.2 1.5 0.009 16.3 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM79009.1 - 5.1e-06 26.1 5.7 0.0011 18.7 0.8 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM79009.1 - 4e-05 23.4 1.8 0.22 11.5 0.3 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFM79009.1 - 5.8e-05 22.8 2.5 0.07 12.9 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM79009.1 - 0.00036 20.5 4.7 0.03 14.4 1.2 2.1 1 1 1 2 2 2 2 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM79009.1 - 0.0025 17.9 2.7 1.3 9.2 0.3 2.5 2 0 0 2 2 2 2 DBF zinc finger zf-Di19 PF05605.12 KFM79009.1 - 0.0031 17.8 5.1 0.036 14.4 2.3 2.1 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DUF4764 PF15961.5 KFM79009.1 - 0.0046 15.7 2.9 0.1 11.3 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4764) zf-C2H2_6 PF13912.6 KFM79009.1 - 0.0047 16.9 9.3 0.34 10.9 2.1 2.6 2 2 0 2 2 2 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFM79009.1 - 0.013 15.1 3.9 0.97 9.1 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM79009.1 - 0.019 15.3 5.1 1.2 9.5 1.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KFM79009.1 - 0.026 14.6 4.0 0.087 13.0 4.0 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-MYST PF17772.1 KFM79009.1 - 0.06 13.0 2.3 2.7 7.6 0.2 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain GAGA PF09237.11 KFM79009.1 - 0.084 12.7 0.7 1.8 8.5 0.2 2.1 1 1 1 2 2 2 0 GAGA factor zf-BED PF02892.15 KFM79009.1 - 0.089 12.8 10.5 0.6 10.2 2.3 2.3 1 1 1 2 2 2 0 BED zinc finger HTH_5 PF01022.20 KFM79009.1 - 0.18 11.7 1.7 8.3 6.4 0.1 2.2 1 1 1 2 2 2 0 Bacterial regulatory protein, arsR family Lon_C PF05362.13 KFM79010.1 - 3.3e-80 268.5 1.2 7.4e-80 267.3 1.2 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KFM79010.1 - 1.3e-24 87.3 0.0 2.1e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KFM79010.1 - 2.9e-21 76.3 0.0 8.6e-21 74.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM79010.1 - 5.5e-07 29.7 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM79010.1 - 7.1e-06 26.5 1.7 0.00044 20.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KFM79010.1 - 3.7e-05 23.6 0.0 0.00016 21.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KFM79010.1 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KFM79010.1 - 0.00018 21.6 0.0 0.00079 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFM79010.1 - 0.00076 19.8 0.0 0.0066 16.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFM79010.1 - 0.0029 17.5 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase RuvB_N PF05496.12 KFM79010.1 - 0.0038 17.0 0.0 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 KFM79010.1 - 0.009 15.0 0.1 0.034 13.1 0.0 1.8 2 0 0 2 2 2 1 PrkA AAA domain AAA_18 PF13238.6 KFM79010.1 - 0.016 15.8 0.0 0.039 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KFM79010.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase IstB_IS21 PF01695.17 KFM79010.1 - 0.077 12.7 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFM79010.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFM79010.1 - 0.19 12.1 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase VAR1 PF05316.12 KFM79010.1 - 0.23 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) Homeodomain PF00046.29 KFM79011.1 - 1.6e-09 37.5 0.8 1.6e-09 37.5 0.8 2.0 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 KFM79014.1 - 1.5e-21 76.0 8.5 2.7e-21 75.2 8.5 1.4 1 0 0 1 1 1 1 Homeodomain SPOC PF07744.13 KFM79016.1 - 2.9e-38 131.2 0.0 2.1e-37 128.4 0.0 2.3 3 0 0 3 3 3 1 SPOC domain RRM_1 PF00076.22 KFM79016.1 - 7.9e-28 96.1 0.9 8.5e-11 41.5 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM79016.1 - 1.3e-05 25.1 0.0 0.0044 17.1 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFM79016.1 - 0.0026 17.7 0.1 0.11 12.5 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFM79016.1 - 0.02 15.0 0.0 2.2 8.5 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif HTH_Tnp_Tc5 PF03221.16 KFM79017.1 - 8.7e-08 32.1 0.2 9.1e-08 32.0 0.2 1.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Glyco_hydro_47 PF01532.20 KFM79018.1 - 1.1e-118 397.0 0.0 1.8e-118 396.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Spaetzle PF16077.5 KFM79019.1 - 1.9e-07 31.5 1.6 1.9e-06 28.3 0.2 2.3 2 0 0 2 2 2 1 Spaetzle Coagulin PF02035.15 KFM79019.1 - 0.0021 18.0 0.1 0.005 16.8 0.1 1.6 2 0 0 2 2 2 1 Coagulin SK_channel PF03530.14 KFM79021.1 - 4.1e-11 42.9 0.1 5.2e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated SK potassium channel DPPIV_N PF00930.21 KFM79022.1 - 9.6e-89 297.6 0.1 1.3e-88 297.2 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFM79022.1 - 2.8e-50 170.7 2.8 4.7e-50 170.0 2.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KFM79022.1 - 7.1e-05 22.5 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KFM79022.1 - 0.00021 21.0 0.5 0.0022 17.6 0.5 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KFM79022.1 - 0.00057 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PAF-AH_p_II PF03403.13 KFM79022.1 - 0.0008 18.0 0.0 0.0012 17.4 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 KFM79022.1 - 0.042 13.7 0.1 0.26 11.1 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.8 KFM79022.1 - 0.05 12.8 0.8 2.8 7.0 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2920) Hydrolase_4 PF12146.8 KFM79022.1 - 0.057 12.7 0.0 1.5 8.0 0.0 2.2 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFM79022.1 - 0.058 13.2 0.4 3.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KFM79022.1 - 0.068 13.8 0.0 0.28 11.8 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family AA_permease_2 PF13520.6 KFM79022.1 - 0.18 10.6 0.2 0.29 9.9 0.2 1.2 1 0 0 1 1 1 0 Amino acid permease Pkinase_Tyr PF07714.17 KFM79024.1 - 2.3e-89 299.1 0.0 3.4e-89 298.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM79024.1 - 2.5e-39 135.2 0.0 3.8e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFM79024.1 - 7.7e-27 93.2 0.0 5e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM79024.1 - 2.7e-22 79.2 0.1 1.9e-11 44.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM79024.1 - 1.1e-17 64.1 0.1 7.5e-11 42.2 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM79024.1 - 2.7e-15 56.3 0.0 3.3e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM79024.1 - 2.8e-12 46.8 0.1 0.00043 20.4 0.1 4.2 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM79024.1 - 3.1e-05 24.3 0.0 0.031 14.7 0.0 2.5 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM79024.1 - 4.4e-05 23.0 0.0 0.0083 15.7 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 KFM79024.1 - 0.00031 20.9 0.0 0.01 16.1 0.0 2.6 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM79024.1 - 0.0013 18.8 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFM79024.1 - 0.0054 16.8 0.0 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain LapA_dom PF06305.11 KFM79024.1 - 0.056 13.3 0.4 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3290 PF11694.8 KFM79024.1 - 0.15 12.1 0.2 0.32 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) I-set PF07679.16 KFM79025.1 - 4.2e-28 97.2 0.0 9.3e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM79025.1 - 2.5e-23 82.5 0.0 2e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM79025.1 - 7.6e-21 74.1 0.1 4.1e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM79025.1 - 2.7e-20 72.5 0.1 4.4e-09 36.6 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM79025.1 - 1.4e-13 50.9 1.0 3.7e-06 27.1 0.4 3.6 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM79025.1 - 7.5e-07 29.3 0.1 0.0033 17.6 0.0 3.2 2 1 1 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM79025.1 - 9.4e-07 29.2 0.1 0.051 14.0 0.0 2.7 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFM79025.1 - 9.5e-06 25.1 0.0 0.0023 17.5 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM79025.1 - 6.1e-05 23.0 0.0 0.037 14.1 0.0 2.5 2 1 0 2 2 2 2 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFM79025.1 - 0.00017 21.3 0.1 0.077 12.8 0.1 2.3 2 0 0 2 2 2 2 Adenovirus E3 region protein CR1 C2-set_2 PF08205.12 KFM79025.1 - 0.00069 19.6 0.0 0.0018 18.3 0.0 1.9 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain UL141 PF16758.5 KFM79025.1 - 0.044 13.5 0.0 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Herpes-like virus membrane glycoprotein UL141 BatD PF13584.6 KFM79025.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Herpes_gI PF01688.17 KFM79025.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I COX2_TM PF02790.15 KFM79026.1 - 0.012 15.7 1.7 0.015 15.4 0.6 1.7 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain WBP-1 PF11669.8 KFM79026.1 - 0.05 14.2 0.1 0.088 13.4 0.1 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 Stevor PF17410.2 KFM79026.1 - 0.13 11.8 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RIB43A PF05914.12 KFM79027.1 - 4.1e-95 318.7 52.6 4.6e-95 318.5 52.6 1.0 1 0 0 1 1 1 1 RIB43A AAA_assoc_2 PF16193.5 KFM79027.1 - 8.6 6.8 9.2 11 6.4 0.6 3.7 3 0 0 3 3 3 0 AAA C-terminal domain TRAP_alpha PF03896.16 KFM79028.1 - 3.2e-103 344.8 0.4 3.7e-103 344.6 0.4 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SNAP PF14938.6 KFM79031.1 - 0.00012 21.6 1.7 0.00012 21.6 1.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Choline_transpo PF04515.12 KFM79033.1 - 0.078 12.2 1.2 0.099 11.8 1.2 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter Calx-beta PF03160.14 KFM79035.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Calx-beta domain Filament PF00038.21 KFM79036.1 - 0.12 11.9 34.3 0.21 11.1 12.5 2.3 1 1 1 2 2 2 0 Intermediate filament protein Nucleoporin_FG2 PF15967.5 KFM79036.1 - 0.13 10.8 0.3 0.19 10.2 0.3 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeated region DUF223 PF02721.14 KFM79036.1 - 1.9 8.9 5.2 3.3 8.1 0.7 2.7 1 1 2 3 3 3 0 Domain of unknown function DUF223 DUF1640 PF07798.11 KFM79036.1 - 2.2 8.3 28.6 0.23 11.5 15.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Jnk-SapK_ap_N PF09744.9 KFM79036.1 - 3.1 8.0 36.5 0.058 13.6 14.9 2.7 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 HAUS-augmin3 PF14932.6 KFM79036.1 - 3.8 7.0 34.2 5.2 6.6 11.6 3.1 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Tropomyosin_1 PF12718.7 KFM79036.1 - 3.8 7.6 44.8 0.99 9.6 20.4 2.7 1 1 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.12 KFM79036.1 - 4.6 7.3 22.4 0.2 11.7 4.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KFM79036.1 - 5.1 7.5 36.3 1.2e+04 -3.5 36.3 2.2 1 1 0 1 1 1 0 Fez1 HIP1_clath_bdg PF16515.5 KFM79036.1 - 8.6 7.0 36.0 0.48 11.1 14.0 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SEA PF01390.20 KFM79038.1 - 3.4e-09 36.7 0.0 3.2e-08 33.6 0.0 2.9 1 0 0 1 1 1 1 SEA domain zf-H2C2_2 PF13465.6 KFM79039.1 - 9.9e-13 47.9 7.9 2.3e-07 30.9 0.6 4.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79039.1 - 4e-08 33.3 34.3 4.3e-05 23.7 1.7 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 KFM79039.1 - 0.00063 20.0 5.5 0.00063 20.0 5.5 2.1 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 KFM79039.1 - 0.0016 19.1 31.0 0.01 16.6 1.3 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM79039.1 - 0.0097 15.9 16.7 0.1 12.6 2.9 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4119 PF13494.6 KFM79039.1 - 0.57 10.3 3.5 28 4.9 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) zf-BED PF02892.15 KFM79039.1 - 4.5 7.4 15.3 1.4 9.0 2.8 3.0 2 1 1 3 3 3 0 BED zinc finger FAM199X PF15814.5 KFM79039.1 - 5.7 5.9 17.3 0.76 8.8 5.2 2.3 2 0 0 2 2 2 0 Protein family FAM199X YchF-GTPase_C PF06071.13 KFM79040.1 - 8.4e-31 106.0 0.8 1.8e-30 105.0 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KFM79040.1 - 1.3e-22 80.0 0.0 3.6e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM79040.1 - 1.2e-07 31.4 0.0 3.3e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 KFM79040.1 - 0.00099 19.3 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 KFM79040.1 - 0.017 14.1 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KFM79040.1 - 0.064 13.3 0.0 11 6.1 0.0 2.5 1 1 1 2 2 2 0 Dynamin family ABC_tran PF00005.27 KFM79040.1 - 0.12 12.9 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter zf-H2C2_2 PF13465.6 KFM79042.1 - 2.5e-14 52.9 7.7 7.4e-09 35.6 1.1 4.6 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79042.1 - 2.7e-12 46.4 30.3 5.6e-06 26.5 1.0 4.1 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79042.1 - 1.5e-08 34.7 25.8 8.1e-05 23.1 2.1 4.0 4 0 0 4 4 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFM79042.1 - 0.0019 18.5 2.2 0.0019 18.5 2.2 2.9 1 1 2 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFM79042.1 - 0.0039 17.4 3.9 0.69 10.3 0.8 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM79042.1 - 0.0044 17.4 5.5 0.15 12.5 0.7 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM79042.1 - 0.036 14.1 13.7 0.085 12.9 0.8 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM79042.1 - 0.076 12.9 0.2 0.41 10.5 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 KFM79042.1 - 0.1 12.4 13.2 0.24 11.2 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 KFM79042.1 - 0.23 11.6 4.2 0.37 10.9 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 KFM79042.1 - 0.63 10.7 13.1 4.7 7.9 0.3 4.0 3 1 1 4 4 4 0 FOXP coiled-coil domain Elf1 PF05129.13 KFM79042.1 - 1.2 9.2 3.8 1.6 8.8 0.3 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Zn-C2H2_12 PF18112.1 KFM79042.1 - 4.4 7.8 10.3 0.47 11.0 0.7 3.0 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zf-BED PF02892.15 KFM79042.1 - 7.1 6.7 13.3 26 4.9 1.9 3.5 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 KFM79042.1 - 9.5 6.6 10.6 1.2 9.5 1.4 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Dimer_Tnp_hAT PF05699.14 KFM79043.1 - 0.043 13.6 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Exo_endo_phos_2 PF14529.6 KFM79044.1 - 1e-12 47.9 0.2 1.2e-12 47.7 0.2 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM79044.1 - 0.064 12.8 0.0 0.072 12.6 0.0 1.0 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SET PF00856.28 KFM79046.1 - 0.0001 22.7 0.0 0.00047 20.6 0.0 2.0 1 1 0 1 1 1 1 SET domain COX6B PF02297.17 KFM79047.1 - 1.6e-16 60.3 12.0 1.9e-16 60.1 12.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 KFM79047.1 - 0.0055 16.8 6.9 0.0055 16.8 6.9 1.9 2 1 0 2 2 2 1 CHCH domain DB PF01682.19 KFM79047.1 - 0.014 15.7 1.0 0.015 15.5 1.0 1.1 1 0 0 1 1 1 0 DB module CX9C PF16860.5 KFM79047.1 - 0.13 12.3 5.9 0.21 11.6 5.9 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KFM79047.1 - 0.13 12.5 5.6 0.36 11.2 5.7 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DnaJ PF00226.31 KFM79048.1 - 1.8e-17 63.2 0.4 5.5e-17 61.6 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain Zip PF02535.22 KFM79048.1 - 6.5 5.9 5.2 8.6 5.5 5.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CCDC32 PF14989.6 KFM79049.1 - 8.6e-20 71.3 2.7 9.9e-20 71.1 2.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing 32 Sigma54_activ_2 PF14532.6 KFM79049.1 - 0.08 13.1 0.2 18 5.4 0.0 2.7 2 1 1 3 3 3 0 Sigma-54 interaction domain Ras PF00071.22 KFM79050.1 - 2.9e-48 163.5 0.0 6.6e-48 162.4 0.0 1.5 1 1 1 2 2 2 1 Ras family Roc PF08477.13 KFM79050.1 - 6e-21 74.9 0.0 2e-20 73.2 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM79050.1 - 0.0013 18.2 0.0 0.0027 17.2 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family EMP24_GP25L PF01105.24 KFM79051.1 - 4.9e-44 150.4 0.0 6.2e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ELM2 PF01448.24 KFM79052.1 - 1.7e-13 51.1 0.2 8.6e-13 48.8 0.0 2.4 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 KFM79052.1 - 0.0032 17.6 0.0 0.009 16.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFM79052.1 - 0.0073 16.2 0.0 0.032 14.1 0.0 2.1 1 0 0 1 1 1 1 Myb DNA-binding like DUF3570 PF12094.8 KFM79052.1 - 0.031 13.1 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) ELO PF01151.18 KFM79053.1 - 1.9e-33 116.1 18.1 2.3e-33 115.8 18.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ASD2 PF08687.11 KFM79055.1 - 1.6e-75 254.4 18.3 1.6e-75 254.4 18.3 2.5 2 1 0 2 2 2 1 Apx/Shroom domain ASD2 Coatomer_b_Cpla PF14806.6 KFM79055.1 - 0.033 14.2 1.8 0.045 13.7 0.1 2.2 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform Raco_middle PF17651.1 KFM79055.1 - 0.13 11.9 1.4 0.2 11.3 0.2 1.8 2 0 0 2 2 2 0 RACo middle region RNA_pol_Rpb8 PF03870.15 KFM79056.1 - 0.052 13.7 0.0 0.052 13.7 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb8 Ank_2 PF12796.7 KFM79057.1 - 3.4e-05 24.4 0.1 0.0001 22.8 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM79057.1 - 0.011 16.0 0.3 0.067 13.5 0.1 2.3 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KFM79057.1 - 0.13 12.8 0.0 2.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 KFM79057.1 - 0.15 12.6 0.1 0.75 10.4 0.1 2.3 1 1 0 1 1 1 0 Ankyrin repeats (many copies) HlyIII PF03006.20 KFM79059.1 - 2.6e-15 56.7 16.2 3.4e-15 56.4 16.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related FUSC-like PF12805.7 KFM79059.1 - 0.23 10.5 4.3 0.3 10.1 4.3 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS zf-C2H2_4 PF13894.6 KFM79061.1 - 1e-07 32.1 16.1 0.0047 17.6 2.4 3.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM79061.1 - 2.4e-06 27.7 1.2 2.4e-06 27.7 1.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79061.1 - 0.00035 20.8 19.0 0.15 12.6 0.1 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM79061.1 - 0.0037 17.2 12.1 0.062 13.3 0.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFM79061.1 - 0.0088 16.4 1.2 0.0088 16.4 1.2 4.4 3 1 2 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM79061.1 - 0.45 10.9 16.3 5.6 7.4 0.2 4.1 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 KFM79061.1 - 0.79 10.2 9.5 0.37 11.3 0.9 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-met2 PF12907.7 KFM79061.1 - 1.2 9.4 11.7 11 6.2 1.1 3.4 3 0 0 3 3 3 0 Zinc-binding Mito_carr PF00153.27 KFM79062.1 - 2.1e-66 219.9 4.9 6.6e-24 83.7 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Got1 PF04178.12 KFM79063.1 - 4.6e-19 68.9 14.2 5.6e-19 68.6 14.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 KFM79063.1 - 0.0041 17.4 12.4 0.0041 17.4 12.4 2.0 1 1 1 2 2 2 1 Short repeat of unknown function (DUF308) Phage_holin_3_6 PF07332.11 KFM79063.1 - 5.3 7.1 14.6 11 6.1 0.8 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Homeobox_KN PF05920.11 KFM79065.1 - 1.8e-15 56.5 0.4 1.8e-15 56.5 0.4 2.6 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KFM79065.1 - 3.1e-07 30.1 2.2 6.1e-07 29.2 2.2 1.5 1 0 0 1 1 1 1 Homeodomain CobT PF06213.12 KFM79065.1 - 0.43 9.9 9.5 0.9 8.9 9.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 KFM79065.1 - 1.1 7.5 14.6 1.4 7.1 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.8 KFM79065.1 - 1.3 9.1 4.3 3.1 7.8 4.3 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region SAPS PF04499.15 KFM79065.1 - 3.4 6.4 10.9 4.8 5.8 10.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 KFM79065.1 - 8.4 5.0 9.3 14 4.3 9.3 1.3 1 0 0 1 1 1 0 Presenilin Ribosomal_S17 PF00366.20 KFM79067.1 - 0.026 14.6 2.2 0.026 14.6 2.2 2.7 3 1 0 3 3 3 0 Ribosomal protein S17 Arrestin_N PF00339.29 KFM79067.1 - 0.35 10.9 5.3 0.19 11.8 3.1 1.6 1 1 1 2 2 2 0 Arrestin (or S-antigen), N-terminal domain LMBR1 PF04791.16 KFM79067.1 - 0.79 8.6 7.4 0.99 8.2 7.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF836 PF05768.14 KFM79067.1 - 9.6 6.7 7.6 3.3 8.2 1.4 2.5 1 1 2 3 3 3 0 Glutaredoxin-like domain (DUF836) CtaG_Cox11 PF04442.14 KFM79068.1 - 1.3e-59 200.6 0.5 1.3e-59 200.6 0.5 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Cupin_8 PF13621.6 KFM79069.1 - 1.6e-41 142.8 0.0 1.9e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFM79069.1 - 1.3e-07 31.4 0.1 3.8e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein HgmA PF04209.13 KFM79070.1 - 1.4e-132 442.4 0.9 1.6e-132 442.2 0.9 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF1314 PF07013.11 KFM79070.1 - 0.11 12.4 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1314) XAP5 PF04921.14 KFM79071.1 - 5.5e-58 196.7 0.7 6.1e-58 196.6 0.7 1.0 1 0 0 1 1 1 1 XAP5, circadian clock regulator CNDH2_C PF16858.5 KFM79072.1 - 0.89 9.4 18.8 1.2 8.9 18.8 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Noggin PF05806.12 KFM79072.1 - 1.4 8.8 6.1 2.3 8.1 6.1 1.3 1 0 0 1 1 1 0 Noggin ALMT PF11744.8 KFM79072.1 - 3.1 6.5 13.1 3.5 6.3 13.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Anp1 PF03452.14 KFM79073.1 - 3.5e-06 26.6 0.2 0.0024 17.4 0.0 3.0 3 0 0 3 3 3 2 Anp1 2OG-FeII_Oxy_3 PF13640.6 KFM79073.1 - 0.00036 21.4 1.0 0.0011 19.8 0.0 2.3 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Peptidase_M13_N PF05649.13 KFM79076.1 - 3.1e-17 63.3 0.2 3.7e-17 63.1 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM79077.1 - 9.1e-47 160.5 2.2 1e-46 160.4 2.2 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM79078.1 - 1.5e-55 188.0 0.2 2.4e-55 187.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM79078.1 - 4.8e-11 43.0 0.2 8.3e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M13 RNA_pol_A_bac PF01000.26 KFM79079.1 - 7.6e-27 93.9 0.1 2.7e-26 92.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFM79079.1 - 6.8e-21 73.5 0.0 1.7e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cullin_binding PF03556.15 KFM79080.1 - 7.4e-35 120.0 0.5 1.4e-34 119.1 0.5 1.5 1 0 0 1 1 1 1 Cullin binding DDE_Tnp_4 PF13359.6 KFM79081.1 - 1.1e-11 44.6 0.0 1.6e-09 37.6 0.0 2.1 1 1 0 2 2 2 2 DDE superfamily endonuclease TRC8_N PF13705.6 KFM79083.1 - 7.9e-39 133.9 29.3 9e-39 133.7 29.3 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain NS3_envE PF02723.14 KFM79083.1 - 3.1 7.9 10.2 0.13 12.4 2.8 2.6 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E zf-C3HC4_2 PF13923.6 KFM79084.1 - 1e-11 44.5 8.6 1.8e-11 43.7 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM79084.1 - 2e-11 44.0 8.0 3.5e-11 43.3 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFM79084.1 - 9.3e-10 38.7 10.9 1.9e-08 34.4 10.8 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM79084.1 - 2.2e-09 37.0 9.6 3.8e-09 36.3 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TRC8_N PF13705.6 KFM79084.1 - 1.7e-08 33.8 1.4 2.5e-08 33.3 1.4 1.3 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_UBOX PF13445.6 KFM79084.1 - 2.4e-07 30.7 5.6 5.2e-07 29.6 5.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFM79084.1 - 1.1e-06 28.4 5.1 1.7e-06 27.8 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM79084.1 - 6.6e-06 26.0 8.8 1.4e-05 25.0 8.4 1.8 1 1 1 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM79084.1 - 4.5e-05 23.2 6.4 0.00049 19.9 6.7 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFM79084.1 - 0.00022 21.2 6.9 0.0026 17.8 5.3 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFM79084.1 - 0.0021 17.7 4.0 0.0042 16.7 4.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 KFM79084.1 - 0.0023 17.8 0.5 0.81 9.6 0.1 2.3 2 0 0 2 2 2 1 Rad50 zinc hook motif FANCL_C PF11793.8 KFM79084.1 - 0.0024 18.0 8.1 0.014 15.5 8.1 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KFM79084.1 - 0.0067 16.7 4.7 0.012 15.9 4.7 1.5 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-Di19 PF05605.12 KFM79084.1 - 0.0073 16.6 1.7 0.43 10.9 0.3 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_11 PF17123.5 KFM79084.1 - 0.0081 15.9 5.0 0.031 14.0 5.0 2.0 1 1 0 1 1 1 1 RING-like zinc finger RINGv PF12906.7 KFM79084.1 - 0.025 14.7 8.1 0.12 12.5 7.9 2.2 1 1 1 2 2 2 0 RING-variant domain zf-Nse PF11789.8 KFM79084.1 - 0.036 13.9 7.6 0.053 13.3 6.6 1.8 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFM79084.1 - 0.052 13.7 4.3 0.082 13.1 4.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KFM79084.1 - 0.052 13.4 2.5 0.59 10.0 1.6 2.6 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 KFM79084.1 - 0.084 12.6 7.6 1.1 8.9 7.5 2.2 1 1 1 2 2 2 0 P-11 zinc finger GAGA PF09237.11 KFM79084.1 - 0.17 11.7 5.1 0.23 11.3 0.2 2.5 1 1 1 2 2 2 0 GAGA factor DZR PF12773.7 KFM79084.1 - 0.29 11.2 3.8 1.9 8.6 3.8 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-RING-like PF08746.11 KFM79084.1 - 0.35 11.2 8.8 1.9 8.9 8.5 2.2 1 1 1 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.6 KFM79084.1 - 0.79 9.9 7.0 1.6 8.9 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KFM79084.1 - 0.92 9.6 8.2 0.97 9.5 2.9 2.5 2 1 0 2 2 2 0 Zinc-finger zf-RING_4 PF14570.6 KFM79084.1 - 1.8 8.4 8.4 49 3.8 8.4 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Guanylate_cyc_2 PF09778.9 KFM79085.1 - 3.9e-81 271.4 0.9 4.5e-81 271.2 0.9 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 KFM79085.1 - 3.9e-10 40.4 0.0 2.2e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase_C39 like family DUF3335 PF11814.8 KFM79085.1 - 0.00064 19.2 0.0 0.089 12.2 0.0 2.4 2 1 0 2 2 2 2 Peptidase_C39 like family Peptidase_C70 PF12385.8 KFM79085.1 - 0.015 15.3 0.0 0.91 9.5 0.0 2.7 2 1 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 Gln-synt_N_2 PF16952.5 KFM79085.1 - 0.019 14.8 0.0 5.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain Peptidase_C39 PF03412.15 KFM79085.1 - 0.038 13.8 0.1 1.2 9.0 0.0 2.5 3 0 0 3 3 3 0 Peptidase C39 family DUF3920 PF13058.6 KFM79085.1 - 0.11 12.7 0.1 0.38 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) Vps8 PF12816.7 KFM79086.1 - 7.2e-60 201.9 0.2 1.4e-59 201.0 0.2 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KFM79086.1 - 1.7e-05 24.7 4.6 0.06 13.2 0.3 4.3 4 0 0 4 4 4 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KFM79086.1 - 0.0024 18.1 0.0 0.034 14.4 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-H2C2_2 PF13465.6 KFM79087.1 - 4.9e-33 112.1 74.1 7e-06 26.2 0.3 10.5 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79087.1 - 6.6e-28 95.6 75.5 0.00098 19.4 0.6 10.5 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79087.1 - 1.3e-26 90.9 73.7 0.0026 18.4 1.5 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM79087.1 - 4.5e-12 45.9 55.4 0.00081 19.6 2.5 10.1 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM79087.1 - 1.1e-09 38.4 51.9 0.29 11.6 2.2 10.3 10 0 0 10 10 10 5 Zinc-finger of C2H2 type GAGA PF09237.11 KFM79087.1 - 3.5e-05 23.5 18.0 0.083 12.7 0.3 5.4 3 2 2 5 5 5 3 GAGA factor zf-C2H2_6 PF13912.6 KFM79087.1 - 0.005 16.8 75.7 0.032 14.2 0.9 10.2 10 1 0 10 10 10 4 C2H2-type zinc finger HalOD2 PF18547.1 KFM79087.1 - 0.01 15.7 7.5 0.022 14.6 0.1 3.9 4 0 0 4 4 4 0 Halobacterial output domain 2 SDA1 PF05285.12 KFM79087.1 - 0.08 12.4 28.9 0.12 11.8 28.9 1.2 1 0 0 1 1 1 0 SDA1 Caldesmon PF02029.15 KFM79087.1 - 0.22 10.2 24.2 0.31 9.8 24.2 1.1 1 0 0 1 1 1 0 Caldesmon COX5B PF01215.19 KFM79087.1 - 0.72 9.5 7.1 4.1 7.1 0.1 3.2 2 2 1 3 3 3 0 Cytochrome c oxidase subunit Vb zf-C2H2_9 PF16293.5 KFM79087.1 - 0.86 9.5 21.4 5.8 6.8 0.0 7.3 4 2 4 9 9 9 0 C2H2 type zinc-finger (1 copy) Presenilin PF01080.17 KFM79087.1 - 2.4 6.8 22.0 3.6 6.2 22.0 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 KFM79087.1 - 6.8 5.0 19.2 9.4 4.6 19.2 1.3 1 0 0 1 1 1 0 Peptidase family S64 Nop14 PF04147.12 KFM79087.1 - 9.5 4.3 30.0 13 3.8 30.0 1.2 1 0 0 1 1 1 0 Nop14-like family Peptidase_S24 PF00717.23 KFM79088.1 - 2.1e-10 40.4 0.1 3.8e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFM79088.1 - 1.7e-06 27.8 0.0 0.001 18.9 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 PhoLip_ATPase_C PF16212.5 KFM79090.1 - 1.7e-12 47.7 6.4 2e-12 47.4 6.4 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal DUF4449 PF14613.6 KFM79090.1 - 0.071 13.2 0.0 0.089 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Brix PF04427.18 KFM79090.1 - 0.076 13.1 0.0 0.09 12.9 0.0 1.1 1 0 0 1 1 1 0 Brix domain PhoLip_ATPase_C PF16212.5 KFM79091.1 - 1.8e-17 63.9 1.0 2.2e-17 63.7 1.0 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase_3 PF08282.12 KFM79091.1 - 0.00089 19.1 0.1 0.0011 18.7 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM79091.1 - 0.17 12.2 0.1 0.22 11.8 0.1 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFM79092.1 - 9.1e-15 54.5 0.0 3.9e-13 49.3 0.0 2.5 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFM79092.1 - 0.00066 20.0 0.1 0.00097 19.5 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 KFM79095.1 - 9e-28 95.8 3.8 1e-27 95.6 3.8 1.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Autophagy_C PF10381.9 KFM79096.1 - 0.1 12.2 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal DUF5357 PF17310.2 KFM79097.1 - 0.044 12.3 0.0 0.05 12.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5357) zf-H2C2_2 PF13465.6 KFM79098.1 - 3.6e-49 163.1 101.6 5.9e-07 29.6 1.2 13.6 12 2 1 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79098.1 - 1.1e-43 145.3 112.4 2.6e-05 24.4 3.4 12.2 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79098.1 - 1.1e-38 128.5 104.5 0.0007 20.2 1.4 12.2 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM79098.1 - 9.8e-28 95.8 77.7 0.0031 17.8 1.8 12.2 11 1 1 12 12 12 11 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM79098.1 - 9.5e-26 89.4 83.0 0.00086 19.6 0.5 12.3 12 0 0 12 12 12 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM79098.1 - 1.3e-10 41.0 102.3 0.00034 20.5 2.1 13.5 13 1 0 13 13 13 8 C2H2-type zinc finger BolA PF01722.18 KFM79098.1 - 2e-06 28.0 8.9 0.69 10.2 0.1 6.7 3 3 4 7 7 7 1 BolA-like protein C1_1 PF00130.22 KFM79098.1 - 0.098 12.6 57.7 0.34 10.8 1.0 9.8 3 1 8 11 11 11 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MYST PF17772.1 KFM79098.1 - 0.18 11.4 52.2 1.8 8.3 0.8 10.2 5 3 6 11 11 11 0 MYST family zinc finger domain zf_UBZ PF18439.1 KFM79098.1 - 0.34 10.5 48.1 2.2 7.9 0.2 10.3 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger DUF4901 PF16244.5 KFM79098.1 - 0.64 9.3 2.9 0.55 9.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4901) Ta0938 PF11494.8 KFM79098.1 - 4.7 7.5 30.0 5.4 7.3 0.1 7.6 2 1 6 8 8 8 0 Ta0938 zf-C2H2 PF00096.26 KFM79099.1 - 6.7e-44 146.0 81.5 2e-05 24.8 2.3 11.2 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM79099.1 - 7.4e-39 130.5 62.1 6.7e-06 26.3 2.9 12.0 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM79099.1 - 4.9e-35 117.2 76.1 0.00076 20.1 2.0 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM79099.1 - 3e-18 65.5 56.4 0.12 12.8 0.3 11.3 11 0 0 11 11 11 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM79099.1 - 6.3e-13 48.6 54.7 0.0077 16.5 1.2 10.9 11 0 0 11 11 11 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM79099.1 - 6.7e-08 32.3 62.9 0.0026 17.7 0.3 11.1 11 1 0 11 11 11 5 C2H2-type zinc finger BolA PF01722.18 KFM79099.1 - 1.3e-06 28.6 0.8 7.5 6.9 0.0 5.6 3 1 3 6 6 6 2 BolA-like protein zf-Di19 PF05605.12 KFM79099.1 - 0.00014 22.1 51.5 0.08 13.3 0.9 6.2 5 1 1 6 6 6 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFM79099.1 - 0.019 15.2 3.1 0.019 15.2 3.1 5.7 1 1 5 6 6 6 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KFM79099.1 - 0.019 14.7 53.8 0.079 12.7 1.5 8.2 9 0 0 9 9 9 0 zinc-finger C2H2-type GAGA PF09237.11 KFM79099.1 - 0.073 12.9 18.8 2.6 7.9 0.3 5.9 3 1 3 6 6 6 0 GAGA factor zf-C2H2_9 PF16293.5 KFM79099.1 - 0.36 10.7 0.1 0.36 10.7 0.1 7.9 6 4 3 9 9 9 0 C2H2 type zinc-finger (1 copy) zf-FCS PF06467.14 KFM79099.1 - 0.6 10.1 0.1 0.6 10.1 0.1 8.1 7 1 1 8 8 8 0 MYM-type Zinc finger with FCS sequence motif ADK_lid PF05191.14 KFM79099.1 - 2.4 8.2 28.2 2.3 8.3 1.1 6.0 3 1 2 5 5 5 0 Adenylate kinase, active site lid Galactosyl_T PF01762.21 KFM79101.1 - 1e-40 139.7 0.0 1.3e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Pou PF00157.17 KFM79103.1 - 1e-37 127.9 0.1 1.7e-37 127.2 0.1 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFM79103.1 - 2e-18 65.9 0.9 2e-18 65.9 0.9 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFM79103.1 - 0.0085 16.0 0.3 0.035 14.0 0.0 2.2 2 0 0 2 2 2 1 Homeobox KN domain HTH_31 PF13560.6 KFM79103.1 - 0.009 16.3 0.0 0.099 13.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Amino_oxidase PF01593.24 KFM79104.1 - 1.1e-71 242.5 0.0 1.8e-71 241.8 0.0 1.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM79104.1 - 9.5e-15 54.6 0.1 2e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM79104.1 - 8.9e-09 35.4 0.0 1.4e-07 31.4 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM79104.1 - 3.6e-08 33.0 0.4 3.1e-05 23.4 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM79104.1 - 6.6e-07 28.9 0.3 1.4e-06 27.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KFM79104.1 - 9.7e-07 28.2 1.5 1.5e-06 27.6 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFM79104.1 - 3.1e-06 26.6 0.7 4.9e-06 26.0 0.7 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KFM79104.1 - 8.1e-06 25.4 0.3 1.3e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KFM79104.1 - 4.2e-05 22.8 0.0 0.0026 16.9 0.0 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 KFM79104.1 - 0.00019 20.3 0.9 0.0007 18.4 0.4 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KFM79104.1 - 0.00021 21.8 0.4 0.00021 21.8 0.4 2.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KFM79104.1 - 0.00053 18.9 0.0 0.00072 18.5 0.0 1.1 1 0 0 1 1 1 1 MCRA family Lycopene_cycl PF05834.12 KFM79104.1 - 0.0016 17.6 0.1 0.0057 15.7 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KFM79104.1 - 0.0017 17.7 0.2 0.0028 17.0 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KFM79104.1 - 0.0038 17.2 0.0 0.63 10.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KFM79104.1 - 0.014 14.7 1.4 0.1 11.8 0.2 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rho_N PF07498.12 KFM79104.1 - 0.075 13.0 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain XdhC_C PF13478.6 KFM79104.1 - 0.13 12.7 0.0 1.2 9.6 0.0 2.6 2 1 0 2 2 2 0 XdhC Rossmann domain LRR_6 PF13516.6 KFM79107.1 - 3e-05 23.7 2.7 0.044 13.9 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich repeat Sarcoglycan_2 PF05510.13 KFM79108.1 - 0.0013 17.6 0.1 0.0015 17.4 0.1 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon Sarcoglycan_2 PF05510.13 KFM79109.1 - 7.6e-50 169.8 0.0 8.3e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon DUF3446 PF11928.8 KFM79110.1 - 0.053 13.8 7.7 0.067 13.5 7.7 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain Herpes_UL32 PF06070.11 KFM79110.1 - 0.8 7.4 3.9 0.92 7.2 3.9 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DDE_1 PF03184.19 KFM79111.1 - 5.7e-28 97.7 0.1 7.1e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM79111.1 - 0.042 13.6 0.0 0.45 10.2 0.0 2.2 1 1 0 1 1 1 0 DDE superfamily endonuclease DUF1729 PF08354.10 KFM79111.1 - 0.046 12.6 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Pkinase PF00069.25 KFM79112.1 - 1.1e-66 225.0 0.0 1.3e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM79112.1 - 3.6e-35 121.5 0.0 5e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM79112.1 - 2.7e-06 26.9 0.0 0.00085 18.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFM79112.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM79112.1 - 0.11 12.3 0.0 1.2 9.0 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family FAM153 PF15722.5 KFM79112.1 - 0.12 12.8 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 FAM153 family ABC_membrane_2 PF06472.15 KFM79116.1 - 1e-92 310.4 11.4 1.4e-92 309.9 11.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 DUF4179 PF13786.6 KFM79116.1 - 0.039 14.4 0.1 0.42 11.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) 7tm_1 PF00001.21 KFM79118.1 - 1.4e-21 77.0 6.7 2e-21 76.5 6.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM79118.1 - 9.8e-08 31.9 10.3 9.8e-08 31.9 10.3 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFM79118.1 - 1.1e-05 24.9 5.2 1.1e-05 24.9 5.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 KFM79118.1 - 0.00077 19.1 8.3 0.0011 18.5 8.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc Git3 PF11710.8 KFM79118.1 - 0.02 14.7 5.3 0.025 14.3 5.3 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Cytochrom_B_C PF00032.17 KFM79118.1 - 0.071 13.4 1.9 0.11 12.8 1.6 1.4 1 1 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD YuiB PF14068.6 KFM79118.1 - 7 7.3 10.5 3.4 8.3 5.9 2.5 2 1 1 3 3 3 0 Putative membrane protein NO_synthase PF02898.15 KFM79119.1 - 9.4e-172 571.0 0.0 1.1e-171 570.8 0.0 1.0 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.20 KFM79120.1 - 3.5e-60 203.4 0.2 4.7e-60 202.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFM79120.1 - 4.1e-29 101.6 0.0 8.1e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFM79120.1 - 2.5e-16 60.3 0.0 6.1e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFM79120.1 - 0.055 13.6 0.0 0.29 11.2 0.0 2.2 1 1 0 1 1 1 0 Ferric reductase NAD binding domain DUF2685 PF10886.8 KFM79120.1 - 0.07 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) DUF2347 PF09804.9 KFM79126.1 - 7.1e-70 235.8 0.0 9.8e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 KFM79126.1 - 3.5e-12 45.7 4.1 6.8e-05 21.7 0.0 3.1 2 1 1 3 3 3 3 Transport protein Avl9 SPA PF08616.10 KFM79126.1 - 5.7e-12 45.6 0.2 1.2e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Ank_2 PF12796.7 KFM79127.1 - 8.2e-40 135.3 4.6 1.6e-13 51.0 1.6 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM79127.1 - 1e-27 93.1 0.7 2.8e-06 27.2 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KFM79127.1 - 1.2e-27 95.9 7.0 3e-12 46.8 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM79127.1 - 1.8e-27 95.0 6.3 1.6e-09 37.8 0.8 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFM79127.1 - 4.2e-26 90.2 1.0 7.8e-08 32.4 0.0 4.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 KFM79128.1 - 8.1e-05 23.1 0.0 8.3e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM79128.1 - 0.00033 20.9 0.1 0.00046 20.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 KFM79128.1 - 0.00062 20.3 0.1 0.00068 20.2 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM79128.1 - 0.00079 19.7 0.1 0.00083 19.6 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM79128.1 - 0.11 13.0 0.3 0.16 12.5 0.1 1.4 2 0 0 2 2 2 0 Ankyrin repeat KAP_NTPase PF07693.14 KFM79129.1 - 4.1e-07 29.5 0.1 5.3e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 KAP family P-loop domain KAP_NTPase PF07693.14 KFM79130.1 - 6.8e-59 199.7 0.4 9.6e-59 199.2 0.4 1.2 1 0 0 1 1 1 1 KAP family P-loop domain OMS28_porin PF03532.13 KFM79130.1 - 0.0042 16.4 0.4 0.28 10.4 0.0 2.3 2 0 0 2 2 2 2 OMS28 porin NACHT PF05729.12 KFM79130.1 - 0.016 15.1 0.3 0.13 12.1 0.1 2.3 2 1 0 2 2 2 0 NACHT domain SAM_1 PF00536.30 KFM79131.1 - 0.048 14.1 0.1 0.2 12.1 0.1 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Catalase_C PF18011.1 KFM79131.1 - 0.076 12.6 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases KH_8 PF17903.1 KFM79132.1 - 4.7e-05 23.4 0.0 9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFM79132.1 - 0.00018 21.3 0.3 0.00038 20.2 0.3 1.5 1 0 0 1 1 1 1 KH domain ENT PF03735.14 KFM79133.1 - 1.3e-24 86.0 0.4 2.9e-24 84.9 0.2 1.7 2 0 0 2 2 2 1 ENT domain Peptidase_C1 PF00112.23 KFM79134.1 - 1.4e-06 28.5 0.0 1.6e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease bPH_4 PF06713.11 KFM79134.1 - 0.15 12.1 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial PH domain 7tm_1 PF00001.21 KFM79135.1 - 3.1e-60 203.7 6.7 3.6e-60 203.5 6.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM79135.1 - 0.00035 20.3 3.8 0.00035 20.3 3.8 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Hormone_recep PF00104.30 KFM79136.1 - 4.7e-40 137.4 0.1 9.1e-40 136.4 0.1 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFM79136.1 - 5e-32 110.2 16.6 9e-32 109.4 16.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) A_deaminase PF00962.22 KFM79137.1 - 1.3e-12 47.8 0.0 1.4e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase GTP_EFTU_D3 PF03143.17 KFM79138.1 - 1.4e-43 147.8 0.0 2.2e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFM79138.1 - 0.00022 21.5 0.0 0.0015 18.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Semialdhyde_dhC PF02774.18 KFM79138.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain 5HT_transport_N PF03491.13 KFM79138.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus GTP_EFTU PF00009.27 KFM79139.1 - 2.6e-55 187.0 0.0 2.9e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM79139.1 - 3.2e-05 24.0 0.2 0.0011 19.0 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM79139.1 - 0.0033 16.8 0.0 0.0079 15.6 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 KFM79139.1 - 0.042 13.9 0.3 8.5 6.4 0.1 2.3 1 1 1 2 2 2 0 Dynamin family G-alpha PF00503.20 KFM79139.1 - 0.081 12.1 0.2 0.27 10.3 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit VHS PF00790.19 KFM79140.1 - 3.7e-30 104.6 0.2 6.3e-30 103.9 0.2 1.3 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KFM79140.1 - 1.3e-16 59.9 0.0 3e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM79140.1 - 6.7e-13 48.3 0.0 1.3e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM79140.1 - 4.6e-12 45.4 0.1 1.8e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain ENTH PF01417.20 KFM79140.1 - 2.8e-05 24.1 0.0 5.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 ENTH domain SH3_10 PF17902.1 KFM79140.1 - 0.00025 21.0 0.0 0.0009 19.3 0.0 1.9 2 0 0 2 2 2 1 SH3 domain ANTH PF07651.16 KFM79140.1 - 0.02 13.9 0.4 0.03 13.3 0.4 1.2 1 0 0 1 1 1 0 ANTH domain MMS19_N PF14500.6 KFM79140.1 - 0.059 12.9 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II DEPP PF15343.6 KFM79141.1 - 2.3 8.3 9.1 0.088 12.9 1.5 2.1 2 1 0 2 2 2 0 Decidual protein induced by progesterone family DUF4407 PF14362.6 KFM79142.1 - 0.48 9.7 2.2 1.3 8.3 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-ATPase_G PF03179.15 KFM79143.1 - 6.1e-34 116.7 18.2 7e-34 116.5 18.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 KFM79143.1 - 0.072 13.5 14.1 0.089 13.2 14.1 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit P_C10 PF14974.6 KFM79143.1 - 0.23 11.5 4.5 1.2 9.3 0.2 2.3 2 1 0 2 2 2 0 Protein C10 FAA_hydrolase_N PF09298.11 KFM79143.1 - 0.27 11.5 3.4 0.26 11.5 0.2 2.1 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal ATP-synt_B PF00430.18 KFM79143.1 - 9.6 6.3 20.5 2.6 8.1 14.0 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Mut7-C PF01927.16 KFM79144.1 - 3.7e-23 82.2 0.5 2.2e-13 50.6 0.1 2.3 2 0 0 2 2 2 2 Mut7-C RNAse domain DNA_pol_A_exo1 PF01612.20 KFM79144.1 - 4.8e-13 49.2 0.0 2.3e-12 47.0 0.0 2.1 1 1 0 1 1 1 1 3'-5' exonuclease zf-C2HC5 PF06221.13 KFM79144.1 - 0.18 11.8 2.2 29 4.7 0.7 3.3 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type SAS4 PF15460.6 KFM79145.1 - 0.17 12.0 0.9 0.59 10.3 0.0 2.3 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 G-alpha PF00503.20 KFM79146.1 - 3.8e-115 384.8 4.4 4.8e-115 384.5 4.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFM79146.1 - 1.7e-14 53.7 1.1 4.6e-11 42.5 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM79146.1 - 0.00074 18.9 3.7 0.018 14.4 0.1 2.8 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFM79146.1 - 0.026 14.8 0.2 3.9 7.7 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Na_H_Exchanger PF00999.21 KFM79147.1 - 1.3e-06 27.5 4.5 2.1e-06 26.8 4.5 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1180 PF06679.12 KFM79147.1 - 0.0082 16.6 0.1 0.012 16.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) 5TM-5TMR_LYT PF07694.12 KFM79147.1 - 0.02 14.4 0.1 0.02 14.4 0.1 1.6 2 0 0 2 2 2 0 5TMR of 5TMR-LYT Anoctamin PF04547.12 KFM79147.1 - 0.047 12.5 0.2 0.066 12.0 0.2 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel CTV_P33 PF07184.11 KFM79147.1 - 0.069 12.2 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein Na_H_Exchanger PF00999.21 KFM79148.1 - 1.6e-27 96.3 13.9 1.9e-27 96.1 13.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FeoB_C PF07664.12 KFM79148.1 - 0.033 13.9 1.8 0.78 9.5 0.6 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus DUF3021 PF11457.8 KFM79148.1 - 0.69 10.3 6.9 1.7 9.0 6.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) Na_H_Exchanger PF00999.21 KFM79149.1 - 1.9e-05 23.7 1.1 2.5e-05 23.2 1.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CLN3 PF02487.17 KFM79149.1 - 0.02 14.0 0.0 0.026 13.6 0.0 1.0 1 0 0 1 1 1 0 CLN3 protein ATP-synt_E PF05680.12 KFM79152.1 - 7.9e-22 77.4 0.1 9.3e-22 77.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain Zona_pellucida PF00100.23 KFM79153.1 - 1.9e-07 31.2 0.2 1.9e-07 31.2 0.2 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFM79154.1 - 3.8e-12 46.5 0.1 4.7e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain RINGv PF12906.7 KFM79155.1 - 0.17 12.1 0.5 0.17 12.1 0.5 1.9 2 0 0 2 2 2 0 RING-variant domain Pkinase_Tyr PF07714.17 KFM79156.1 - 1.2e-59 201.7 0.0 1.4e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM79156.1 - 5.3e-22 78.4 0.0 6.6e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM79157.1 - 2.7e-19 69.5 0.0 3.1e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM79157.1 - 2.8e-15 56.4 0.0 3.3e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain ABC1 PF03109.16 KFM79157.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 ABC1 family YnfE PF17452.2 KFM79158.1 - 0.035 14.4 0.6 0.048 14.0 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized YnfE-like FCH PF00611.23 KFM79159.1 - 7.1e-09 35.8 0.8 7.1e-09 35.8 0.8 2.9 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain TPR_MLP1_2 PF07926.12 KFM79159.1 - 0.00016 21.7 3.2 0.00016 21.7 3.2 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein TOPRIM_C PF16898.5 KFM79159.1 - 0.036 14.3 1.0 0.036 14.3 1.0 2.1 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM Tox-PLDMTX PF15645.6 KFM79159.1 - 0.094 13.0 0.1 0.53 10.6 0.0 2.1 1 1 1 2 2 2 0 Dermonecrotoxin of the Papain-like fold DUF3685 PF12452.8 KFM79159.1 - 0.12 12.0 0.6 0.23 11.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) DUF745 PF05335.13 KFM79159.1 - 0.13 12.0 2.0 0.16 11.7 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Spc42p PF11544.8 KFM79159.1 - 0.2 11.7 4.0 0.64 10.1 4.0 2.0 1 0 0 1 1 1 0 Spindle pole body component Spc42p DUF4686 PF15742.5 KFM79159.1 - 0.29 10.2 11.4 0.09 11.9 8.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) NOG1_N PF17835.1 KFM79159.1 - 0.41 10.6 4.1 1.3 9.0 3.8 2.0 1 1 0 1 1 1 0 NOG1 N-terminal helical domain CLZ PF16526.5 KFM79159.1 - 0.42 11.0 4.7 0.53 10.7 0.7 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TLE_N PF03920.15 KFM79159.1 - 0.42 10.7 3.3 1.5 8.9 2.9 2.2 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain FapA PF03961.13 KFM79159.1 - 2.2 6.8 6.2 0.95 8.0 1.7 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A APG6_N PF17675.1 KFM79159.1 - 5 7.6 12.6 0.37 11.3 6.4 2.2 2 1 1 3 3 2 0 Apg6 coiled-coil region Ras PF00071.22 KFM79160.1 - 1.7e-59 200.1 0.1 2e-59 199.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM79160.1 - 6.4e-35 120.0 0.1 1.1e-34 119.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM79160.1 - 4.2e-13 49.1 0.1 5.8e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM79160.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM79160.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFM79160.1 - 0.00015 21.8 0.0 0.00026 21.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KFM79160.1 - 0.0019 18.6 0.0 0.4 11.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KFM79160.1 - 0.0023 17.4 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein Septin PF00735.18 KFM79160.1 - 0.031 13.6 0.3 0.092 12.0 0.0 1.8 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 KFM79160.1 - 0.12 11.9 0.0 0.5 9.9 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B CBM_14 PF01607.24 KFM79161.1 - 3.4e-40 136.0 48.0 9.6e-13 48.1 7.9 4.5 4 0 0 4 4 4 4 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 KFM79162.1 - 6.1e-97 317.7 146.8 2.8e-12 46.6 5.9 10.4 10 0 0 10 10 10 10 Chitin binding Peritrophin-A domain GP79 PF17463.2 KFM79162.1 - 0.021 14.8 4.5 1.7 8.7 0.4 3.5 3 0 0 3 3 3 0 Gene product 79 FOXP-CC PF16159.5 KFM79162.1 - 5.3 7.7 17.1 47 4.7 0.2 5.6 5 0 0 5 5 5 0 FOXP coiled-coil domain Mpv17_PMP22 PF04117.12 KFM79163.1 - 1.2e-20 73.4 1.5 2.9e-20 72.2 1.2 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Wtap PF17098.5 KFM79164.1 - 1.2e-31 109.8 6.2 2.3e-31 108.8 3.0 2.5 2 0 0 2 2 2 1 WTAP/Mum2p family UPF0242 PF06785.11 KFM79164.1 - 0.008 16.3 2.1 0.019 15.1 2.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KFM79164.1 - 0.024 14.9 2.1 0.024 14.9 2.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 KFM79164.1 - 0.032 14.5 3.6 0.077 13.3 3.6 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF1664 PF07889.12 KFM79164.1 - 0.11 12.6 0.4 0.29 11.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KFM79164.1 - 3.6 8.3 8.3 6.4 7.5 5.4 2.8 1 1 2 3 3 3 0 SlyX Wtap PF17098.5 KFM79165.1 - 1.8e-28 99.4 3.3 1.8e-28 99.4 3.3 2.0 2 1 0 2 2 2 1 WTAP/Mum2p family DUF2704 PF10866.8 KFM79165.1 - 0.027 14.4 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) DUF1515 PF07439.11 KFM79165.1 - 0.1 12.6 3.4 0.1 12.6 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Exonuc_VII_L PF02601.15 KFM79165.1 - 0.16 11.5 8.6 0.2 11.2 8.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PRKG1_interact PF15898.5 KFM79165.1 - 0.18 12.7 0.3 0.18 12.7 0.3 2.5 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FUSC PF04632.12 KFM79165.1 - 0.58 8.6 3.5 0.68 8.4 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_32 PF13654.6 KFM79165.1 - 0.8 8.4 10.3 1 8.1 10.3 1.1 1 0 0 1 1 1 0 AAA domain TolA_bind_tri PF16331.5 KFM79165.1 - 1.5 8.9 15.7 1.3 9.1 0.1 3.2 2 1 1 3 3 3 0 TolA binding protein trimerisation ADIP PF11559.8 KFM79165.1 - 1.6 8.8 14.8 1.5 8.9 0.1 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Malate_DH PF12434.8 KFM79165.1 - 2.2 8.4 8.3 1.7 8.7 2.3 3.2 3 0 0 3 3 3 0 Malate dehydrogenase enzyme DUF4140 PF13600.6 KFM79165.1 - 3.6 8.1 8.9 9.9e+02 0.3 8.9 2.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Fic PF02661.18 KFM79166.1 - 4.8e-27 94.7 0.1 2.7e-26 92.3 0.0 2.2 2 0 0 2 2 2 1 Fic/DOC family TPR_2 PF07719.17 KFM79166.1 - 0.001 19.0 0.2 0.017 15.2 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM79166.1 - 0.015 15.9 0.0 0.042 14.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM79166.1 - 0.058 14.2 0.0 0.2 12.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 KFM79166.1 - 0.062 13.4 0.2 0.23 11.5 0.2 2.0 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Birna_RdRp PF04197.12 KFM79166.1 - 0.075 11.3 0.1 0.1 10.9 0.1 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) TPR_12 PF13424.6 KFM79166.1 - 0.096 13.0 0.2 0.4 11.0 0.1 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM79166.1 - 0.1 13.0 0.1 0.73 10.4 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM79166.1 - 0.11 12.4 0.2 1.2 9.1 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Sod_Fe_C PF02777.18 KFM79167.1 - 2.5e-35 120.7 0.0 4.2e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFM79167.1 - 1.8e-32 111.7 0.8 3e-32 110.9 0.8 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain FATC PF02260.20 KFM79168.1 - 3.5e-16 58.7 0.3 5.8e-16 58.0 0.1 1.5 2 0 0 2 2 2 1 FATC domain PI3_PI4_kinase PF00454.27 KFM79168.1 - 0.0079 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3_PI4_kinase PF00454.27 KFM79169.1 - 1.1e-12 48.3 0.0 1.2e-12 48.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ArsR PF09824.9 KFM79171.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator Phageshock_PspG PF09583.10 KFM79172.1 - 0.052 13.8 0.5 0.062 13.6 0.5 1.2 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) TAN PF11640.8 KFM79176.1 - 0.00048 20.3 0.1 0.00063 19.9 0.1 1.3 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair PID_2 PF14719.6 KFM79177.1 - 1.5e-14 54.3 0.0 2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 KFM79177.1 - 1.5e-14 54.2 0.6 3.5e-14 53.0 0.0 1.8 2 1 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFM79177.1 - 7.8e-06 26.1 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain Tctex-1 PF03645.13 KFM79178.1 - 0.15 12.3 1.4 0.75 10.1 0.2 2.2 2 0 0 2 2 2 0 Tctex-1 family Ubiq-assoc PF09145.10 KFM79179.1 - 0.021 14.8 0.1 0.054 13.5 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-associated Anophelin PF10731.9 KFM79180.1 - 0.00044 20.0 0.0 0.00081 19.2 0.0 1.4 1 0 0 1 1 1 1 Thrombin inhibitor from mosquito PBP_GOBP PF01395.22 KFM79180.1 - 0.001 19.2 2.1 0.0016 18.6 2.1 1.3 1 0 0 1 1 1 1 PBP/GOBP family CALCOCO1 PF07888.11 KFM79182.1 - 0.00023 20.2 17.7 0.00048 19.1 17.8 1.4 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.9 KFM79182.1 - 0.036 13.2 9.4 0.047 12.8 9.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5395 PF17373.2 KFM79182.1 - 0.037 14.7 0.4 0.13 13.0 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5395) Abi_C PF14355.6 KFM79182.1 - 0.056 13.6 0.5 0.45 10.6 0.1 2.4 2 1 1 3 3 3 0 Abortive infection C-terminus GAS PF13851.6 KFM79182.1 - 0.086 12.2 27.5 0.1 12.0 21.2 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 KFM79182.1 - 0.39 9.3 18.5 0.5 8.9 17.8 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A AATF-Che1 PF13339.6 KFM79182.1 - 2.7 8.7 16.0 1 10.0 11.5 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF2205 PF10224.9 KFM79182.1 - 2.9 8.0 14.7 0.29 11.1 0.5 3.2 2 1 2 4 4 4 0 Short coiled-coil protein HSP70 PF00012.20 KFM79182.1 - 3.2 5.8 14.7 3.9 5.5 14.7 1.0 1 0 0 1 1 1 0 Hsp70 protein Spc7 PF08317.11 KFM79182.1 - 3.2 6.5 23.7 3.3 6.5 21.7 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 KFM79182.1 - 4.3 6.6 14.1 0.19 11.0 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) kleA_kleC PF17383.2 KFM79182.1 - 7.4 7.0 7.2 23 5.4 1.0 2.8 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A TSC22 PF01166.18 KFM79182.1 - 7.4 7.0 16.8 0.1 12.9 1.5 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF3347 PF11827.8 KFM79182.1 - 7.6 6.7 14.0 6.7 6.9 12.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) zf-3CxxC_2 PF17180.4 KFM79184.1 - 2.5e-27 95.4 10.2 2.5e-27 95.4 10.2 2.1 2 1 0 2 2 2 1 Zinc-binding domain zf-CCHC_2 PF13696.6 KFM79184.1 - 8e-12 44.7 5.4 8e-12 44.7 5.4 3.3 5 0 0 5 5 5 1 Zinc knuckle zf-CCHC PF00098.23 KFM79184.1 - 0.073 13.2 1.3 0.073 13.2 1.3 3.3 4 0 0 4 4 4 0 Zinc knuckle zf-CHY PF05495.12 KFM79184.1 - 0.61 10.6 19.6 0.72 10.4 3.6 2.3 2 0 0 2 2 2 0 CHY zinc finger zf-3CxxC PF13695.6 KFM79184.1 - 6 7.4 26.1 0.33 11.5 15.7 3.2 2 2 0 2 2 2 0 Zinc-binding domain Calpain_III PF01067.22 KFM79186.1 - 1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 KFM79187.1 - 7.4e-72 241.9 0.0 8.1e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 KFM79188.1 - 5.3e-11 42.1 0.1 6.1e-11 41.9 0.1 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease RGS-like PF09128.11 KFM79191.1 - 1.3e-52 178.2 0.0 3.7e-52 176.8 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain PH_16 PF17838.1 KFM79191.1 - 2e-47 160.1 2.5 4.4e-47 159.0 2.5 1.6 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 KFM79191.1 - 2.2e-36 125.8 2.4 2.2e-36 125.8 2.4 3.0 3 0 0 3 3 3 1 RhoGEF domain PDZ_6 PF17820.1 KFM79191.1 - 6.9e-14 51.4 0.2 1.7e-13 50.2 0.2 1.7 1 0 0 1 1 1 1 PDZ domain C1_1 PF00130.22 KFM79191.1 - 9.2e-13 47.9 10.9 1.7e-12 47.0 10.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PDZ PF00595.24 KFM79191.1 - 3.7e-12 46.4 0.5 9.2e-12 45.2 0.5 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM79191.1 - 1.2e-07 32.0 0.3 4.7e-07 30.0 0.3 2.0 1 0 0 1 1 1 1 PDZ domain PH_13 PF16652.5 KFM79191.1 - 3.7e-06 26.8 1.9 1.3e-05 25.1 1.9 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain RGS PF00615.19 KFM79191.1 - 5.1e-06 26.7 1.9 9.5e-06 25.9 0.0 2.5 3 0 0 3 3 2 1 Regulator of G protein signaling domain PH PF00169.29 KFM79191.1 - 0.002 18.6 0.8 0.0078 16.7 0.2 2.5 2 0 0 2 2 1 1 PH domain C1_2 PF03107.16 KFM79191.1 - 0.019 15.3 5.3 0.05 13.9 5.3 1.7 1 0 0 1 1 1 0 C1 domain STAT_alpha PF01017.20 KFM79191.1 - 0.038 13.9 0.1 0.038 13.9 0.1 3.5 3 0 0 3 3 3 0 STAT protein, all-alpha domain CCDC-167 PF15188.6 KFM79191.1 - 0.24 11.7 5.7 0.81 10.1 0.1 3.5 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 CsgA PF17334.2 KFM79191.1 - 5.9 7.7 10.6 0.44 11.3 1.5 3.9 4 0 0 4 4 3 0 Minor curli fiber component A ABC_membrane PF00664.23 KFM79192.1 - 2.8e-39 135.4 7.0 3.4e-39 135.1 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Cyt_bd_oxida_II PF02322.15 KFM79192.1 - 0.038 13.3 5.2 0.066 12.6 5.2 1.3 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II CobD_Cbib PF03186.13 KFM79192.1 - 0.048 12.9 1.9 0.14 11.4 0.2 2.0 2 0 0 2 2 2 0 CobD/Cbib protein Spec3 PF15795.5 KFM79196.1 - 0.013 16.0 2.7 0.02 15.4 2.7 1.3 1 0 0 1 1 1 0 Ectodermal ciliogenesis protein WD40 PF00400.32 KFM79198.1 - 3.2e-36 122.7 22.7 1.3e-05 25.8 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM79198.1 - 1.2e-14 54.4 3.6 0.03 14.6 0.3 5.5 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM79198.1 - 9.5e-09 35.4 2.0 0.0089 15.9 0.3 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFM79198.1 - 0.0028 16.7 0.0 0.89 8.5 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4653 PF15546.6 KFM79201.1 - 0.093 12.3 0.5 0.14 11.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Cadherin-like PF12733.7 KFM79205.1 - 0.12 12.9 0.0 0.16 12.5 0.0 1.1 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain Pkinase_Tyr PF07714.17 KFM79206.1 - 1.8e-34 119.2 0.1 2.5e-34 118.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM79206.1 - 4.1e-31 108.3 0.0 6e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFM79206.1 - 9e-11 41.1 0.6 1.8e-10 40.1 0.6 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFM79206.1 - 2e-10 41.6 7.1 2e-10 41.6 7.1 2.1 2 0 0 2 2 2 1 Activin types I and II receptor domain FTA2 PF13095.6 KFM79206.1 - 0.00017 21.3 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KFM79206.1 - 0.00022 20.1 0.0 0.00039 19.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM79206.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cadherin_C_2 PF16492.5 KFM79206.1 - 0.1 13.4 0.1 0.37 11.6 0.1 2.0 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DBB PF14545.6 KFM79207.1 - 3.6e-32 111.2 0.1 8.5e-32 110.0 0.1 1.7 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, TIR_3 PF18567.1 KFM79207.1 - 1.8e-10 40.9 0.5 3.8e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Toll/interleukin-1 receptor domain Ank_5 PF13857.6 KFM79207.1 - 0.0043 17.3 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM79207.1 - 0.0084 16.7 0.1 0.018 15.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM79207.1 - 0.029 14.9 0.1 0.27 11.9 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat PHD_Oberon PF07227.11 KFM79207.1 - 0.048 13.6 3.4 0.18 11.7 3.4 1.9 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein SAM_1 PF00536.30 KFM79208.1 - 3e-08 34.0 0.3 5.7e-08 33.1 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM79208.1 - 3.6e-05 23.8 0.5 8.1e-05 22.7 0.5 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KH_1 PF00013.29 KFM79209.1 - 1.1e-20 73.2 0.2 3.5e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_10 PF17905.1 KFM79209.1 - 0.04 14.4 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 GLD-3 KH domain 5 ERAP1_C PF11838.8 KFM79211.1 - 3e-07 30.3 0.0 3.3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain ERAP1_C PF11838.8 KFM79212.1 - 0.00044 19.9 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFM79213.1 - 2.6e-69 233.1 2.7 4.5e-69 232.3 2.7 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFM79213.1 - 3.1e-50 171.0 0.6 4.7e-50 170.4 0.6 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 KFM79213.1 - 1e-19 71.3 0.1 1.6e-19 70.7 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF1360 PF07098.11 KFM79213.1 - 0.17 11.9 0.4 0.92 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Synaptobrevin PF00957.21 KFM79214.1 - 1e-23 82.9 1.6 1.1e-23 82.8 1.6 1.0 1 0 0 1 1 1 1 Synaptobrevin Seryl_tRNA_N PF02403.22 KFM79214.1 - 0.036 14.3 0.5 0.036 14.3 0.5 1.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MCU PF04678.13 KFM79214.1 - 0.12 12.5 0.4 0.11 12.6 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Somatomedin_B PF01033.17 KFM79216.1 - 2.7e-07 30.8 16.2 2.7e-07 30.8 16.2 3.2 3 0 0 3 3 3 1 Somatomedin B domain 7tm_2 PF00002.24 KFM79217.1 - 1.1e-24 87.1 17.8 1.7e-24 86.5 17.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Wzy_C_2 PF11846.8 KFM79217.1 - 1.7 8.5 4.6 24 4.8 0.0 3.0 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF5317 PF17248.2 KFM79217.1 - 2.3 8.2 10.2 0.44 10.5 0.9 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5317) WW_1 PF18507.1 KFM79218.1 - 0.087 12.5 1.2 0.18 11.5 0.2 2.0 2 0 0 2 2 2 0 WW domain CHCH PF06747.13 KFM79218.1 - 0.093 12.9 0.6 0.093 12.9 0.6 3.5 3 1 1 4 4 4 0 CHCH domain EGF_CA PF07645.15 KFM79219.1 - 2.7e-11 43.5 2.4 2.7e-11 43.5 2.4 12.8 9 3 4 13 13 13 2 Calcium-binding EGF domain EGF_3 PF12947.7 KFM79219.1 - 0.00016 21.8 10.4 0.00016 21.8 10.4 12.6 13 1 0 13 13 13 4 EGF domain EGF PF00008.27 KFM79219.1 - 0.00035 20.8 20.6 0.00057 20.1 7.7 12.8 12 1 0 12 12 12 6 EGF-like domain cEGF PF12662.7 KFM79219.1 - 0.0018 18.1 10.1 0.0093 15.9 1.0 9.8 13 0 0 13 13 13 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFM79219.1 - 0.0022 18.2 8.6 0.0022 18.2 8.6 12.9 9 3 3 12 12 12 6 Coagulation Factor Xa inhibitory site zf-C3HC4_3 PF13920.6 KFM79221.1 - 2.7e-15 55.9 9.2 4.9e-15 55.1 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM79221.1 - 1.4e-07 31.2 10.4 3e-07 30.2 10.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFM79221.1 - 6e-06 26.5 11.6 1.2e-05 25.5 11.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM79221.1 - 0.003 17.5 9.8 0.006 16.5 9.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM79221.1 - 0.037 13.9 11.4 0.077 12.8 11.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 KFM79221.1 - 0.078 12.4 5.1 1.1 8.8 2.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-P11 PF03854.14 KFM79221.1 - 0.09 12.5 8.1 0.21 11.3 8.1 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 KFM79221.1 - 0.12 12.1 9.1 0.24 11.2 9.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFM79221.1 - 0.23 11.2 3.0 0.61 9.9 1.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger MRP-S32 PF10210.9 KFM79225.1 - 2.9e-27 95.1 0.5 3.7e-27 94.7 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 DUF1828 PF08861.10 KFM79225.1 - 0.17 12.2 0.0 7.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF1828 CPG4 PF15481.6 KFM79227.1 - 0.48 11.1 9.9 0.28 11.8 0.6 2.9 1 1 2 3 3 3 0 Chondroitin proteoglycan 4 TLD PF07534.16 KFM79229.1 - 8.9e-16 58.4 0.0 2.1e-15 57.2 0.0 1.5 2 0 0 2 2 2 1 TLD BACK PF07707.15 KFM79229.1 - 2.5e-14 53.2 0.4 1.3e-10 41.3 0.0 2.3 1 1 1 2 2 2 2 BTB And C-terminal Kelch Glu-tRNAGln PF02686.15 KFM79229.1 - 0.19 12.0 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Ank_2 PF12796.7 KFM79230.1 - 3.6e-31 107.6 0.6 1.4e-11 44.8 0.1 4.0 2 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM79230.1 - 1.4e-26 92.5 0.9 1.1e-07 32.2 0.0 5.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM79230.1 - 1.1e-23 80.7 0.4 0.072 13.7 0.0 8.2 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 KFM79230.1 - 2.8e-22 78.1 0.1 0.0075 16.7 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KFM79230.1 - 1.5e-19 69.8 2.6 0.00022 21.5 0.1 6.7 3 2 5 8 8 8 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFM79230.1 - 0.19 12.1 0.3 0.19 12.1 0.3 2.0 2 0 0 2 2 2 0 SOCS box Adap_comp_sub PF00928.21 KFM79231.1 - 1.9e-26 93.0 0.5 2.9e-26 92.4 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFM79231.1 - 3.2e-07 30.4 0.6 5.5e-07 29.6 0.4 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KFM79231.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF5539 PF17693.1 KFM79231.1 - 0.16 11.6 0.3 0.23 11.1 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Peptidase_M13_N PF05649.13 KFM79233.1 - 2.1e-13 50.7 0.0 2.2e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM79235.1 - 0.00049 19.8 0.0 0.00049 19.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Chromo_shadow PF01393.19 KFM79236.1 - 9.2e-33 112.1 3.4 3e-30 104.1 0.0 2.7 2 1 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFM79236.1 - 1.7e-23 82.2 4.3 1.1e-18 66.9 2.6 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFM79236.1 - 0.0071 16.5 0.1 2.5 8.3 0.1 2.3 2 0 0 2 2 2 2 Polycomb-like MTF2 factor 2 Pkinase PF00069.25 KFM79237.1 - 4.8e-42 144.1 0.0 7.8e-42 143.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM79237.1 - 4.2e-12 45.9 0.0 7.2e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase L27 PF02828.16 KFM79237.1 - 2.4e-06 27.2 0.2 6.6e-06 25.8 0.2 1.8 1 0 0 1 1 1 1 L27 domain Kinase-like PF14531.6 KFM79237.1 - 0.009 15.4 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFM79237.1 - 0.055 12.2 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KFM79237.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CLN3 PF02487.17 KFM79238.1 - 7.6e-131 436.8 22.3 5.5e-130 434.0 22.3 1.9 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KFM79238.1 - 2e-05 23.7 22.1 0.0011 18.0 8.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily EF-hand_7 PF13499.6 KFM79239.1 - 0.00016 22.1 0.2 0.00032 21.1 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM79239.1 - 0.001 18.4 0.4 0.0032 16.9 0.4 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFM79239.1 - 0.0012 18.6 0.4 0.0044 16.8 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KFM79239.1 - 0.0012 18.2 0.8 0.0012 18.2 0.8 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFM79239.1 - 0.0029 17.4 0.1 0.009 15.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair DRY_EERY PF09750.9 KFM79240.1 - 1.1e-38 132.6 0.0 1.1e-38 132.6 0.0 4.3 3 2 0 4 4 4 1 Alternative splicing regulator DUF2457 PF10446.9 KFM79240.1 - 0.01 15.0 0.7 0.01 15.0 0.7 6.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2457) zf-C2H2 PF00096.26 KFM79241.1 - 1.5e-19 69.3 61.1 4.9e-06 26.7 2.8 6.1 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM79241.1 - 5.3e-12 45.6 60.2 1.6e-07 31.4 1.5 7.8 9 0 0 9 9 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM79241.1 - 5e-07 30.0 69.6 0.0056 17.4 2.8 7.3 7 0 0 7 7 5 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM79241.1 - 5.3e-07 29.3 31.6 3.9e-05 23.3 4.4 4.7 4 0 0 4 4 4 3 C2H2-type zinc-finger domain NOA36 PF06524.12 KFM79241.1 - 0.0018 17.6 15.5 0.0018 17.6 15.5 2.7 3 0 0 3 3 3 1 NOA36 protein GAGA PF09237.11 KFM79241.1 - 0.0024 17.6 10.4 0.036 13.9 1.2 3.4 2 1 1 3 3 3 2 GAGA factor DUF3268 PF11672.8 KFM79241.1 - 0.0053 17.1 15.4 0.066 13.5 0.8 2.8 2 1 1 3 3 3 2 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 KFM79241.1 - 0.034 14.4 28.4 0.88 9.9 1.9 5.7 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_7 PF15269.6 KFM79241.1 - 0.15 12.2 14.7 0.36 11.0 1.4 3.2 2 1 1 3 3 3 0 Zinc-finger zf-C2H2_9 PF16293.5 KFM79241.1 - 2.9 7.8 9.6 1.3 9.0 1.1 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM79241.1 - 5.7 7.1 15.6 3.3 7.9 0.2 4.5 4 1 1 5 5 5 0 Sec23/Sec24 zinc finger IBR PF01485.21 KFM79244.1 - 8.4e-19 67.6 25.8 2.5e-13 50.0 9.5 6.0 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain CAP PF00188.26 KFM79245.1 - 5.9e-21 75.6 1.2 9.8e-21 74.9 1.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family EAGR_box PF16713.5 KFM79245.1 - 0.044 13.5 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Enriched in aromatic and glycine Residues box DUF1573 PF07610.11 KFM79245.1 - 0.082 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) WD40 PF00400.32 KFM79246.1 - 4.3e-53 176.1 27.1 1.1e-09 38.8 0.1 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM79246.1 - 1.2e-28 99.2 2.8 3.3e-07 30.5 0.1 6.0 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KFM79246.1 - 3.4e-10 39.5 0.1 1.1e-08 34.7 0.1 2.5 2 0 0 2 2 2 1 LisH eIF2A PF08662.11 KFM79246.1 - 3.5e-10 40.1 1.9 0.0036 17.2 0.2 3.8 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFM79246.1 - 5.3e-06 25.6 4.3 0.023 13.7 0.0 3.6 2 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFM79246.1 - 4.8e-05 22.8 0.0 0.36 10.1 0.0 3.2 4 0 0 4 4 4 2 WD40-like domain Coatomer_WDAD PF04053.14 KFM79246.1 - 0.001 18.2 0.4 0.1 11.6 0.0 2.5 3 0 0 3 3 3 1 Coatomer WD associated region PD40 PF07676.12 KFM79246.1 - 0.027 14.4 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_hydro_11 PF00457.17 KFM79246.1 - 0.058 13.0 0.6 6.3 6.4 0.0 2.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 Nup160 PF11715.8 KFM79246.1 - 0.058 12.0 6.8 6.3 5.3 0.0 4.6 2 2 3 6 6 6 0 Nucleoporin Nup120/160 IKI3 PF04762.12 KFM79246.1 - 0.28 9.1 0.7 1.5 6.7 0.1 2.4 2 1 1 3 3 3 0 IKI3 family Collagen PF01391.18 KFM79247.1 - 8.2e-15 54.3 51.8 1.1e-08 34.7 34.0 3.4 3 1 0 3 3 3 2 Collagen triple helix repeat (20 copies) EMI PF07546.13 KFM79247.1 - 4e-05 24.3 1.9 6.3e-05 23.7 1.9 1.3 1 0 0 1 1 1 1 EMI domain MTP18 PF10558.9 KFM79248.1 - 2.4e-14 53.7 1.2 1e-08 35.3 0.4 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) zf-RING_9 PF13901.6 KFM79249.1 - 3.9e-65 219.7 9.0 9.5e-65 218.4 9.0 1.7 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon RUN PF02759.19 KFM79249.1 - 4.2e-20 72.1 0.0 1.8e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 RUN domain Zf_RING PF16744.5 KFM79249.1 - 0.059 13.5 8.6 0.43 10.7 5.6 3.0 2 0 0 2 2 2 0 KIAA1045 RING finger ArdA PF07275.11 KFM79249.1 - 0.22 12.1 5.6 0.51 10.9 2.4 2.7 3 0 0 3 3 3 0 Antirestriction protein (ArdA) RNHCP PF12647.7 KFM79249.1 - 4.3 7.4 12.2 0.68 9.9 5.3 2.6 2 0 0 2 2 2 0 RNHCP domain C1_2 PF03107.16 KFM79249.1 - 9 6.7 25.0 0.6 10.5 8.7 3.5 2 1 0 2 2 2 0 C1 domain Tubulin PF00091.25 KFM79250.1 - 8.8e-68 228.4 0.0 1.2e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM79250.1 - 2.5e-52 176.3 0.0 3.9e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFM79250.1 - 0.00095 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 KFM79251.1 - 8.4e-33 112.0 0.0 4.5e-19 68.0 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM79251.1 - 8.9e-08 32.1 0.0 0.0093 16.0 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 KFM79251.1 - 0.0008 19.4 0.0 0.0066 16.4 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFM79251.1 - 0.00084 19.4 0.0 0.0034 17.5 0.0 2.0 2 2 1 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 KFM79251.1 - 0.038 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif ClpS PF02617.17 KFM79251.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS DAP3 PF10236.9 KFM79252.1 - 2.5e-70 237.2 0.0 2.8e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 KFM79252.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KFM79252.1 - 0.031 14.7 0.7 0.48 10.8 0.7 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFM79252.1 - 0.044 13.3 0.0 0.072 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFM79252.1 - 0.066 12.9 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KFM79252.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KFM79252.1 - 0.092 12.5 0.1 0.18 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM79252.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_13 PF13166.6 KFM79252.1 - 0.11 11.2 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFM79252.1 - 0.11 12.5 0.1 5 7.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Spaetzle PF16077.5 KFM79253.1 - 1.4e-28 99.2 2.6 2.5e-28 98.5 2.6 1.4 1 0 0 1 1 1 1 Spaetzle 7tm_3 PF00003.22 KFM79254.1 - 3.5e-67 226.6 19.2 4.6e-67 226.2 19.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFM79254.1 - 3.7e-12 46.0 11.0 7.6e-12 45.0 11.0 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ycf70 PF17382.2 KFM79254.1 - 0.21 12.0 1.4 1.8 9.1 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized Ycf70-like DUF2663 PF10864.8 KFM79254.1 - 3.3 8.1 5.4 33 4.9 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) ANF_receptor PF01094.28 KFM79256.1 - 3.9e-65 220.3 0.1 4.8e-65 220.0 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KFM79256.1 - 7.8e-07 29.1 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 KFM79257.1 - 1.8e-64 217.7 30.4 2.2e-64 217.4 30.4 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFM79257.1 - 1.3e-09 37.8 10.3 1.3e-09 37.8 10.3 1.8 1 1 1 2 2 2 2 Nine Cysteines Domain of family 3 GPCR PEMT PF04191.13 KFM79257.1 - 5.2 7.5 8.4 0.51 10.8 0.2 3.2 3 1 2 5 5 5 0 Phospholipid methyltransferase zf-MYND PF01753.18 KFM79258.1 - 7.8e-09 35.5 10.7 7.8e-09 35.5 10.7 2.7 2 0 0 2 2 2 1 MYND finger SET PF00856.28 KFM79258.1 - 0.00014 22.3 0.2 0.00014 22.3 0.2 2.3 1 1 1 2 2 2 1 SET domain TPR_12 PF13424.6 KFM79258.1 - 0.0028 17.9 0.0 0.006 16.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3989 PF13150.6 KFM79258.1 - 0.092 12.5 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Coronavirus_5 PF05528.11 KFM79258.1 - 0.26 11.3 2.3 0.31 11.0 0.4 2.2 2 0 0 2 2 2 0 Coronavirus gene 5 protein PSP94 PF05825.11 KFM79258.1 - 1.7 9.3 10.8 0.16 12.6 4.0 2.4 2 0 0 2 2 2 0 Beta-microseminoprotein (PSP-94) Carboxyl_trans PF01039.22 KFM79259.1 - 7e-90 302.0 0.0 8.1e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Chordopox_E11 PF06138.12 KFM79260.1 - 0.016 15.5 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus E11 protein DUF3847 PF12958.7 KFM79260.1 - 0.062 13.4 0.1 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Na_trans_cytopl PF11933.8 KFM79261.1 - 1.4e-09 38.1 5.4 1.6e-08 34.6 0.8 2.1 1 1 1 2 2 2 2 Cytoplasmic domain of voltage-gated Na+ ion channel Ion_trans PF00520.31 KFM79262.1 - 4e-20 72.1 0.1 4.6e-20 71.9 0.1 1.0 1 0 0 1 1 1 1 Ion transport protein PPP4R2 PF09184.11 KFM79263.1 - 1e-50 173.0 34.4 2.3e-49 168.6 34.4 2.2 1 1 0 1 1 1 1 PPP4R2 BBS1 PF14779.6 KFM79265.1 - 5.1e-38 131.0 0.1 1.4e-36 126.3 0.0 2.1 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 KFM79265.1 - 5.8e-06 26.3 0.2 0.0065 16.5 0.0 2.5 1 1 2 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 KFM79265.1 - 0.02 14.3 0.1 0.98 8.7 0.0 2.6 1 1 1 2 2 2 0 PTHB1 N-terminus PQQ_3 PF13570.6 KFM79265.1 - 0.09 13.3 0.3 93 3.7 0.0 3.8 4 1 0 4 4 4 0 PQQ-like domain ELO PF01151.18 KFM79268.1 - 4e-42 144.5 22.9 4e-33 115.0 13.5 2.0 1 1 1 2 2 2 2 GNS1/SUR4 family DUF1129 PF06570.11 KFM79268.1 - 1.1 8.7 11.7 0.086 12.3 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) ELO PF01151.18 KFM79270.1 - 1e-51 175.9 27.6 1.2e-51 175.7 27.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family AA_permease_2 PF13520.6 KFM79270.1 - 0.025 13.4 11.4 0.027 13.3 1.4 2.1 2 0 0 2 2 2 0 Amino acid permease ELO PF01151.18 KFM79271.1 - 2.9e-25 89.2 9.2 3.3e-25 89.0 9.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 KFM79273.1 - 2.3e-52 178.0 21.6 2.7e-52 177.8 21.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Lipocalin_2 PF08212.12 KFM79274.1 - 0.011 15.6 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Lipocalin-like domain Lipocalin PF00061.23 KFM79275.1 - 1e-08 35.5 0.1 1.2e-08 35.2 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 KFM79275.1 - 8.7e-05 22.4 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Triabin Lipocalin_2 PF08212.12 KFM79275.1 - 0.00049 20.0 0.3 0.0013 18.7 0.3 1.7 1 1 0 1 1 1 1 Lipocalin-like domain 3HCDH_N PF02737.18 KFM79276.1 - 1.5e-49 168.4 0.0 2.9e-49 167.4 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFM79276.1 - 2.2e-15 57.1 0.1 4.6e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 KFM79276.1 - 6.9e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KFM79276.1 - 8.3e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 KFM79276.1 - 0.00087 18.9 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KFM79276.1 - 0.00095 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.15 KFM79276.1 - 0.0024 18.0 0.0 0.005 17.0 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KFM79276.1 - 0.0086 15.7 0.0 0.043 13.5 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KFM79276.1 - 0.018 15.6 0.0 0.045 14.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 KFM79276.1 - 0.031 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spermine_synth PF01564.17 KFM79276.1 - 0.035 13.5 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Spermine/spermidine synthase domain AlaDh_PNT_C PF01262.21 KFM79276.1 - 0.049 12.9 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CbiA PF01656.23 KFM79276.1 - 0.065 13.3 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pyr_redox PF00070.27 KFM79276.1 - 0.091 13.3 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM79276.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KFM79276.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ig_3 PF13927.6 KFM79277.1 - 3.4e-33 114.1 5.2 8.9e-12 45.4 0.1 4.6 3 1 2 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 KFM79277.1 - 2.7e-31 107.7 3.3 5.9e-09 36.2 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain C2-set_2 PF08205.12 KFM79277.1 - 4e-28 97.3 0.7 8.9e-14 51.3 0.0 3.3 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFM79277.1 - 1.6e-24 85.9 4.8 4.6e-07 29.9 0.2 4.2 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 KFM79277.1 - 1.2e-23 82.9 0.2 1.5e-07 31.3 0.0 4.4 3 1 2 5 5 5 4 Immunoglobulin I-set domain C1-set PF07654.15 KFM79277.1 - 3.4e-18 65.8 0.8 1.5e-05 25.3 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin C1-set domain V-set PF07686.17 KFM79277.1 - 9.3e-16 58.0 7.0 0.00017 21.8 0.0 6.4 4 3 1 5 5 5 3 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM79277.1 - 4.8e-06 26.7 0.0 5.7 7.3 0.0 5.2 4 2 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM79277.1 - 0.00055 20.3 1.3 2.7 8.5 0.1 4.3 4 2 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFM79277.1 - 0.0038 17.3 0.0 3.1 7.9 0.0 3.9 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_Tie2_1 PF10430.9 KFM79277.1 - 0.01 16.2 0.0 0.076 13.4 0.0 2.2 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 Lep_receptor_Ig PF06328.11 KFM79277.1 - 0.027 14.4 0.1 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 Ig-like C2-type domain Big_3_5 PF16640.5 KFM79277.1 - 2.1 8.6 11.5 2 8.6 0.8 3.6 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Ig_2 PF13895.6 KFM79279.1 - 2.3e-24 85.5 2.6 3.9e-07 30.3 0.0 4.4 4 1 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.6 KFM79279.1 - 2.9e-23 82.2 1.2 1.9e-08 34.8 0.3 4.5 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 KFM79279.1 - 1.2e-14 54.1 0.1 0.0035 17.4 0.0 4.9 4 2 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 KFM79279.1 - 8.1e-13 48.4 5.3 0.0033 17.6 0.0 5.4 4 2 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFM79279.1 - 0.00053 20.1 0.5 6 7.1 0.0 4.0 4 0 0 4 4 4 1 Immunoglobulin V-set domain V-set_CD47 PF08204.11 KFM79279.1 - 0.00092 19.2 1.1 0.73 9.8 0.0 3.8 3 1 0 3 3 3 1 CD47 immunoglobulin-like domain C2-set_2 PF08205.12 KFM79279.1 - 0.0012 18.9 1.2 0.22 11.6 0.1 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM79279.1 - 0.02 14.5 0.1 6.6 6.4 0.0 2.7 3 0 0 3 3 3 0 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM79279.1 - 0.027 14.5 0.3 0.28 11.2 0.0 2.7 4 0 0 4 4 4 0 C17orf99 Ig domain C1-set PF07654.15 KFM79279.1 - 0.14 12.6 0.3 35 4.9 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin C1-set domain RabGAP-TBC PF00566.18 KFM79280.1 - 6.6e-28 97.8 16.9 2.5e-25 89.4 16.9 2.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain ASFV_L11L PF05293.11 KFM79280.1 - 5.6 7.4 5.8 24 5.4 0.4 2.6 1 1 1 2 2 2 0 African swine fever virus (ASFV) L11L protein LRR_8 PF13855.6 KFM79281.1 - 0.028 14.2 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Leucine rich repeat SNF2_N PF00176.23 KFM79282.1 - 6.4e-14 51.4 0.0 6.4e-14 51.4 0.0 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain Metal_resist PF13801.6 KFM79282.1 - 0.25 11.5 4.9 0.51 10.5 4.9 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Helicase_C PF00271.31 KFM79283.1 - 5.3e-14 52.5 0.3 3.8e-13 49.8 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dynamin_M PF01031.20 KFM79285.1 - 1.7e-53 181.7 5.4 3e-53 180.9 5.4 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFM79285.1 - 1.8e-24 86.7 0.0 6.8e-24 84.8 0.0 2.1 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFM79285.1 - 5.7e-12 45.6 0.9 1e-10 41.6 0.3 2.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFM79285.1 - 0.058 13.5 0.1 0.41 10.7 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase CUB PF00431.20 KFM79287.1 - 5.5e-10 39.6 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 CUB domain wnt PF00110.19 KFM79288.1 - 5e-63 213.5 20.6 5.6e-63 213.4 20.6 1.0 1 0 0 1 1 1 1 wnt family zf-U11-48K PF05253.12 KFM79289.1 - 2.2e-18 65.7 8.8 2.3e-10 40.1 0.2 2.5 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger Tyr-DNA_phospho PF06087.12 KFM79291.1 - 2.4e-130 435.2 0.1 3.8e-130 434.6 0.1 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-CCHH PF10283.9 KFM79291.1 - 6.6e-12 45.2 7.7 1.4e-11 44.1 7.7 1.6 1 0 0 1 1 1 1 PBZ domain WRNPLPNID PF15017.6 KFM79291.1 - 0.25 12.2 5.0 0.46 11.4 5.0 1.5 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF1619 PF07773.11 KFM79292.1 - 6.1e-23 82.2 10.6 6.1e-23 82.2 10.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1619) DUF1619 PF07773.11 KFM79293.1 - 1.2e-05 25.4 0.0 9e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1619) Pyr_redox_2 PF07992.14 KFM79294.1 - 2.9e-47 161.3 0.0 3.4e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM79294.1 - 8.3e-08 32.7 0.0 4.8e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM79294.1 - 0.013 14.8 0.0 0.092 12.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mito_fiss_Elm1 PF06258.11 KFM79294.1 - 0.17 11.0 0.0 3.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission ELM1 NAD_binding_9 PF13454.6 KFM79294.1 - 0.23 11.4 0.0 6.6 6.7 0.0 2.5 1 1 1 2 2 2 0 FAD-NAD(P)-binding Rep_fac_C PF08542.11 KFM79295.1 - 1.5e-26 92.6 0.1 1.9e-25 89.1 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 KFM79295.1 - 2.7e-14 53.7 0.1 4.5e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFM79295.1 - 1.1e-12 48.0 0.0 3e-11 43.4 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KFM79295.1 - 2.6e-06 27.5 0.1 2.4e-05 24.4 0.0 2.2 2 1 0 3 3 2 1 Rad17 P-loop domain AAA_14 PF13173.6 KFM79295.1 - 1.2e-05 25.4 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM79295.1 - 2e-05 25.1 0.0 0.0025 18.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFM79295.1 - 2.3e-05 24.2 0.0 5.7e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KFM79295.1 - 3.3e-05 23.7 0.0 6.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM79295.1 - 6.6e-05 23.5 0.1 0.0031 18.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFM79295.1 - 6.9e-05 22.3 0.0 0.0019 17.6 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KFM79295.1 - 0.0002 21.6 0.6 1 9.7 0.2 2.6 1 1 0 2 2 2 2 AAA domain AAA_assoc_2 PF16193.5 KFM79295.1 - 0.00048 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain TniB PF05621.11 KFM79295.1 - 0.0016 17.9 0.1 1.2 8.6 0.1 2.3 2 0 0 2 2 2 2 Bacterial TniB protein AAA_5 PF07728.14 KFM79295.1 - 0.0018 18.3 0.1 0.0042 17.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KFM79295.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM79295.1 - 0.0021 18.4 0.7 0.017 15.4 0.6 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KFM79295.1 - 0.0028 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.13 KFM79295.1 - 0.0045 16.8 0.3 0.0082 15.9 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DEAD PF00270.29 KFM79295.1 - 0.0091 15.8 2.0 0.93 9.2 0.0 3.3 2 1 1 4 4 4 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KFM79295.1 - 0.013 14.2 0.2 2.4 6.8 0.0 2.6 2 1 0 3 3 3 0 SNF2 family N-terminal domain AAA_25 PF13481.6 KFM79295.1 - 0.021 14.4 0.2 0.089 12.4 0.1 1.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM79295.1 - 0.021 15.3 0.0 0.06 13.9 0.0 1.7 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 KFM79295.1 - 0.044 13.7 2.0 0.17 11.8 0.2 2.5 2 1 1 3 3 3 0 NTPase MeaB PF03308.16 KFM79295.1 - 0.06 12.3 0.0 0.19 10.7 0.0 1.6 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 KFM79295.1 - 0.067 13.2 0.1 12 5.9 0.0 2.9 1 1 1 3 3 3 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KFM79295.1 - 0.086 12.5 0.1 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_3 PF07726.11 KFM79295.1 - 0.086 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFM79295.1 - 0.14 11.9 0.5 0.52 10.0 0.5 1.8 1 1 0 1 1 1 0 AAA domain MipZ PF09140.11 KFM79295.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ YL1 PF05764.13 KFM79296.1 - 2.2e-36 126.2 33.0 2.2e-36 126.2 33.0 1.8 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 KFM79296.1 - 2.2e-08 33.7 0.2 6.2e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain RNase_H PF00075.24 KFM79297.1 - 0.0025 18.0 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 RNase H FOP_dimer PF09398.10 KFM79298.1 - 2e-13 50.4 0.6 5.2e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KFM79298.1 - 0.00034 19.6 0.1 0.00068 18.6 0.1 1.5 1 0 0 1 1 1 1 LisH cNMPbd_u2 PF16643.5 KFM79298.1 - 0.018 15.5 0.8 0.018 15.5 0.8 2.0 2 1 0 2 2 2 0 Unstructured region on cNMP-binding protein FYVE_2 PF02318.16 KFM79300.1 - 9.6e-22 77.4 16.0 2.5e-21 76.1 16.0 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger DUF5595 PF18077.1 KFM79300.1 - 0.0037 17.3 0.2 0.024 14.7 0.2 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5595) zf-UDP PF14569.6 KFM79300.1 - 0.74 10.0 5.4 2.2 8.5 5.4 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE PF01363.21 KFM79300.1 - 1.6 8.9 16.5 5.4 7.2 16.1 2.1 1 1 0 1 1 1 0 FYVE zinc finger MARVEL PF01284.23 KFM79301.1 - 1.4e-07 31.6 16.9 1.8e-07 31.3 16.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain SLATT_fungal PF18142.1 KFM79301.1 - 0.023 14.7 1.3 0.023 14.7 1.3 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Tmemb_170 PF10190.9 KFM79301.1 - 0.027 14.8 4.6 0.027 14.8 4.6 1.9 1 1 1 2 2 2 0 Putative transmembrane protein 170 Fam20C PF06702.12 KFM79303.1 - 1.6e-24 87.0 1.9 2.1e-24 86.6 1.9 1.1 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 RdRP PF05183.12 KFM79304.1 - 3.9e-165 550.8 0.0 5.6e-165 550.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.12 KFM79305.1 - 7.9e-163 543.2 0.0 1.2e-162 542.6 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase REC104 PF17378.2 KFM79305.1 - 0.055 13.3 0.1 0.22 11.3 0.1 2.1 1 0 0 1 1 1 0 Meiotic recombination protein REC104 XPG_I PF00867.18 KFM79305.1 - 0.062 13.7 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 XPG I-region QIL1 PF15884.5 KFM79305.1 - 0.1 13.2 0.1 0.71 10.5 0.0 2.5 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 EGF PF00008.27 KFM79306.1 - 5.9e-43 144.8 103.0 9.1e-09 35.5 6.5 8.6 8 0 0 8 8 8 7 EGF-like domain Laminin_G_1 PF00054.23 KFM79306.1 - 3e-27 95.4 0.0 4.4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFM79306.1 - 1.8e-26 93.2 0.1 2.6e-26 92.6 0.1 1.2 1 0 0 1 1 1 1 Laminin G domain LRR_8 PF13855.6 KFM79306.1 - 3.2e-26 90.9 27.5 2.4e-13 49.6 7.4 2.6 1 1 2 3 3 3 3 Leucine rich repeat hEGF PF12661.7 KFM79306.1 - 1.2e-23 82.8 87.0 1.1e-06 29.1 1.1 9.8 9 0 0 9 9 8 6 Human growth factor-like EGF LRR_4 PF12799.7 KFM79306.1 - 4.1e-07 30.2 10.5 0.00028 21.2 5.2 2.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM79306.1 - 9.9e-07 28.4 2.0 1.9e-06 27.5 2.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat EGF_3 PF12947.7 KFM79306.1 - 2.7e-05 24.2 97.1 0.0057 16.8 4.6 8.9 7 2 1 8 8 8 6 EGF domain LRRNT PF01462.18 KFM79306.1 - 3.2e-05 23.5 1.0 3.2e-05 23.5 1.0 4.7 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFM79306.1 - 0.00016 21.7 6.4 0.31 11.7 0.4 4.6 3 0 0 3 3 3 1 Leucine Rich Repeat EGF_2 PF07974.13 KFM79306.1 - 0.00039 20.7 30.3 0.0024 18.2 10.3 9.1 9 0 0 9 9 8 5 EGF-like domain FXa_inhibition PF14670.6 KFM79306.1 - 0.011 16.1 93.5 0.12 12.7 5.7 8.4 6 2 1 7 7 7 0 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 KFM79306.1 - 0.018 15.1 9.0 0.018 15.1 9.0 7.9 8 0 0 8 8 6 0 MSP1 EGF domain 1 LRR_6 PF13516.6 KFM79306.1 - 0.026 14.6 6.6 6.8 7.0 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat SecY PF00344.20 KFM79307.1 - 2.6e-77 260.1 12.3 3.5e-77 259.7 12.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFM79307.1 - 7.6e-19 67.3 0.2 2.3e-18 65.7 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2975 PF11188.8 KFM79307.1 - 3.7 7.4 10.8 0.45 10.4 2.1 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2975) SH2 PF00017.24 KFM79308.1 - 4.5e-14 52.3 0.1 1.8e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 SH2 domain RasGEF PF00617.19 KFM79308.1 - 1e-13 51.9 0.0 1.8e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain SAM_1 PF00536.30 KFM79308.1 - 4.4e-06 27.0 0.2 8.6e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM79308.1 - 3.6e-05 23.8 0.3 7.7e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LRR_4 PF12799.7 KFM79309.1 - 0.00019 21.7 13.0 2 9.0 0.1 5.0 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM79309.1 - 0.022 14.8 9.5 0.079 13.1 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich repeat Herpes_gI PF01688.17 KFM79309.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I YidD PF01809.18 KFM79309.1 - 0.2 11.6 2.1 0.32 10.9 1.0 1.9 2 1 0 2 2 2 0 Putative membrane protein insertion efficiency factor Sad1_UNC PF07738.13 KFM79312.1 - 4e-31 107.8 0.0 9.8e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4457 PF14652.6 KFM79312.1 - 0.035 13.4 0.0 0.12 11.6 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4457) PIN_12 PF16289.5 KFM79312.1 - 0.038 14.5 0.7 0.038 14.5 0.7 2.5 2 0 0 2 2 2 0 PIN domain Lant_dehydr_C PF14028.6 KFM79312.1 - 0.073 12.6 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Baculo_PEP_C PF04513.12 KFM79312.1 - 0.33 11.0 6.4 0.046 13.8 1.9 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 KFM79312.1 - 0.49 11.0 8.2 2 9.1 4.2 3.2 1 1 1 2 2 2 0 SlyX Spidroin_N PF16763.5 KFM79313.1 - 3.2e-45 153.2 6.5 5.9e-45 152.3 6.5 1.4 1 0 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term Spidroin_MaSp PF11260.8 KFM79313.1 - 4.8e-28 97.3 10.6 4.8e-28 97.3 10.6 2.8 2 1 2 4 4 4 1 Major ampullate spidroin 1 and 2 SOUL PF04832.12 KFM79314.1 - 1e-32 113.6 0.2 1.2e-32 113.5 0.2 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein SOUL PF04832.12 KFM79315.1 - 1.3e-43 149.1 0.5 1.5e-43 148.9 0.5 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein YXWGXW PF12779.7 KFM79315.1 - 0.039 14.1 0.3 0.081 13.1 0.3 1.5 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) SOUL PF04832.12 KFM79316.1 - 1.2e-34 120.0 0.3 1.3e-34 119.8 0.3 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein zf-PHD-like PF15446.6 KFM79317.1 - 0.0036 16.9 1.7 0.0041 16.8 1.7 1.2 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Cor1 PF04803.12 KFM79319.1 - 4e-19 69.1 14.7 4e-19 69.1 14.7 1.3 2 0 0 2 2 2 1 Cor1/Xlr/Xmr conserved region Hist_deacetyl PF00850.19 KFM79320.1 - 8.1e-83 278.4 0.1 1.1e-82 278.0 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain TPPII PF12580.8 KFM79321.1 - 9.2e-73 243.8 0.4 1.4e-72 243.2 0.4 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II Peptidase_S8 PF00082.22 KFM79321.1 - 2.4e-34 118.9 1.3 3.3e-34 118.5 1.3 1.2 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 KFM79322.1 - 8e-37 127.1 0.0 9.4e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Subtilase family FGase PF05013.12 KFM79322.1 - 0.18 12.0 0.0 0.76 9.9 0.0 1.8 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase Aminotran_5 PF00266.19 KFM79323.1 - 9e-46 156.5 0.0 1.1e-45 156.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KFM79323.1 - 0.0038 16.5 0.0 0.039 13.1 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II TM1506 PF08973.10 KFM79323.1 - 0.14 11.9 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1893) zf-H2C2_2 PF13465.6 KFM79324.1 - 1.9e-103 334.7 130.8 4e-09 36.5 0.2 17.1 17 0 0 17 17 17 17 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79324.1 - 1.2e-66 217.6 158.8 5.4e-05 23.4 0.3 17.1 17 0 0 17 17 17 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79324.1 - 2.9e-52 170.8 147.9 0.00049 20.7 0.4 17.0 17 0 0 17 17 17 16 C2H2-type zinc finger zf-met PF12874.7 KFM79324.1 - 2.1e-26 91.5 115.1 0.00015 22.0 0.7 17.5 17 0 0 17 17 17 10 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM79324.1 - 6.9e-24 83.3 120.8 0.034 14.2 4.3 17.7 17 1 0 17 17 17 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM79324.1 - 5.1e-23 80.8 98.4 0.0048 17.2 0.1 17.4 16 1 1 17 17 17 9 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM79324.1 - 3.4e-08 33.2 40.1 0.21 11.4 0.1 11.2 4 3 9 13 13 13 5 GAGA factor zf-C2HC_2 PF13913.6 KFM79324.1 - 6.5e-07 29.1 75.1 0.97 9.4 0.1 16.1 17 0 0 17 17 17 3 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM79324.1 - 8.6e-06 25.6 53.7 0.25 11.4 0.7 9.9 4 3 6 10 10 10 5 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KFM79324.1 - 4.1e-05 23.5 72.0 0.19 11.8 0.1 15.2 11 5 6 17 17 17 4 Sec23/Sec24 zinc finger BolA PF01722.18 KFM79324.1 - 0.00014 22.1 29.0 13 6.2 0.2 9.6 1 1 7 9 9 9 0 BolA-like protein zf-C2H2_9 PF16293.5 KFM79324.1 - 0.00021 21.0 72.3 0.36 10.7 0.2 15.2 3 3 13 16 16 16 2 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFM79324.1 - 0.00058 19.6 8.1 0.0067 16.2 1.7 11.4 14 0 0 14 14 13 2 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM79324.1 - 0.0013 18.4 100.5 0.064 13.0 0.1 15.8 16 0 0 16 16 16 7 C2H2-type zinc-finger domain zf-RRPl_C4 PF17026.5 KFM79324.1 - 0.0082 16.2 73.7 0.12 12.5 8.6 7.1 1 1 5 7 7 7 4 Putative ribonucleoprotein zinc-finger pf C4 type Zn-C2H2_12 PF18112.1 KFM79324.1 - 0.025 15.0 0.1 0.025 15.0 0.1 14.4 16 0 0 16 16 16 0 Autophagy receptor zinc finger-C2H2 domain DUF960 PF06124.11 KFM79324.1 - 0.035 14.8 2.6 7.2 7.3 0.1 4.4 4 1 1 5 5 5 0 Staphylococcal protein of unknown function (DUF960) DUF2256 PF10013.9 KFM79324.1 - 0.047 13.8 73.2 8 6.7 0.2 15.8 17 0 0 17 17 16 0 Uncharacterized protein conserved in bacteria (DUF2256) MCR_D PF02505.14 KFM79324.1 - 0.066 13.1 4.0 25 4.7 0.1 4.9 3 3 1 4 4 4 0 Methyl-coenzyme M reductase operon protein D zf-C2H2_2 PF12756.7 KFM79324.1 - 0.095 13.0 111.0 1.9 8.9 0.8 15.0 1 1 12 14 14 14 0 C2H2 type zinc-finger (2 copies) Nore1-SARAH PF16517.5 KFM79324.1 - 0.13 12.2 1.0 36 4.4 0.0 4.7 6 0 0 6 6 6 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DUF952 PF06108.12 KFM79324.1 - 1.7 8.7 6.3 1.7e+02 2.3 0.0 5.6 5 2 1 6 6 6 0 Protein of unknown function (DUF952) zf-CHCC PF10276.9 KFM79324.1 - 2.7 8.1 30.2 15 5.8 0.0 11.1 16 0 0 16 16 15 0 Zinc-finger domain zf-met PF12874.7 KFM79325.1 - 9.3e-32 108.5 31.5 1.4e-08 34.9 1.0 6.5 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM79325.1 - 3.7e-27 94.0 30.4 4e-07 30.2 1.8 6.7 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM79325.1 - 5.7e-22 78.0 41.0 9.9e-05 22.6 4.5 6.1 1 1 3 6 6 6 6 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFM79325.1 - 1.9e-17 62.6 30.8 0.00011 22.4 0.6 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79325.1 - 1.2e-16 60.0 23.3 0.027 15.3 0.3 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger OrsD PF12013.8 KFM79325.1 - 3e-06 27.6 19.5 0.78 10.2 0.7 5.2 1 1 3 5 5 5 4 Orsellinic acid/F9775 biosynthesis cluster protein D zf-DBF PF07535.12 KFM79325.1 - 1.2e-05 25.3 34.9 0.012 15.7 1.3 6.4 6 0 0 6 6 6 5 DBF zinc finger C1_2 PF03107.16 KFM79325.1 - 0.0011 19.2 18.2 0.18 12.2 0.5 6.1 6 0 0 6 6 6 1 C1 domain TF_Zn_Ribbon PF08271.12 KFM79325.1 - 0.0048 16.4 11.3 0.027 14.0 0.3 3.6 3 0 0 3 3 3 2 TFIIB zinc-binding Trm112p PF03966.16 KFM79325.1 - 0.0049 17.4 3.4 0.15 12.7 0.7 3.7 3 1 0 3 3 3 1 Trm112p-like protein C1_1 PF00130.22 KFM79325.1 - 0.12 12.3 12.0 5 7.1 0.0 5.2 6 0 0 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_9 PF16293.5 KFM79325.1 - 0.17 11.8 12.9 9.1 6.2 0.0 5.7 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-U1 PF06220.12 KFM79325.1 - 0.48 10.2 0.1 0.48 10.2 0.1 5.6 6 0 0 6 6 6 0 U1 zinc finger PyrI_C PF02748.15 KFM79325.1 - 0.59 10.1 14.4 0.8 9.7 0.4 4.7 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AD PF07776.15 KFM79325.1 - 1.4 9.3 9.8 0.78 10.0 0.2 3.8 4 1 0 4 4 4 0 Zinc-finger associated domain (zf-AD) C1_4 PF07975.12 KFM79325.1 - 4.3 7.6 19.2 11 6.3 0.0 5.7 6 0 0 6 6 6 0 TFIIH C1-like domain VATC PF18716.1 KFM79325.1 - 4.7 7.2 20.1 8.1 6.4 0.2 5.6 6 0 0 6 6 6 0 Vms1-associating treble clef domain His_Me_b4a2 PF18275.1 KFM79325.1 - 5.7 7.1 9.7 1.5 8.9 0.2 4.0 4 0 0 4 4 4 0 His-Me finger endonuclease beta4-alpha2 domain zf-H2C2_2 PF13465.6 KFM79326.1 - 3e-72 236.0 72.5 6.6e-10 39.0 0.4 10.2 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79326.1 - 1.6e-40 135.3 105.8 7.6e-06 26.1 1.7 10.2 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79326.1 - 4.2e-27 92.5 95.1 0.00093 19.8 1.2 10.1 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM79326.1 - 3.1e-26 90.8 75.5 1.4e-06 28.2 0.8 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFM79326.1 - 1.4e-13 50.7 74.5 0.012 16.0 0.4 9.9 10 0 0 10 10 9 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM79326.1 - 1.5e-12 47.4 58.0 0.03 14.6 1.1 9.7 8 1 1 9 9 9 6 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 KFM79326.1 - 0.00018 21.5 26.4 10 6.3 0.1 8.8 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 KFM79326.1 - 0.00019 20.9 36.4 0.78 9.4 0.2 8.7 9 0 0 9 9 8 3 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM79326.1 - 0.00023 21.2 31.2 0.043 13.9 2.0 4.1 1 1 3 4 4 4 2 Putative ribonucleoprotein zinc-finger pf C4 type C1_4 PF07975.12 KFM79326.1 - 0.00059 20.0 3.6 0.00059 20.0 3.6 6.0 3 2 2 6 6 6 1 TFIIH C1-like domain ADK_lid PF05191.14 KFM79326.1 - 0.003 17.5 35.4 0.82 9.7 1.1 6.7 2 1 7 9 9 9 6 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 KFM79326.1 - 0.0089 16.1 27.5 0.15 12.2 0.7 6.4 4 2 2 6 6 6 2 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFM79326.1 - 0.019 14.8 29.4 21 5.1 0.1 9.1 9 0 0 9 9 9 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM79326.1 - 0.02 15.6 31.8 3 8.7 0.3 4.9 1 1 5 6 6 6 0 zinc-ribbon family DUF3268 PF11672.8 KFM79326.1 - 0.17 12.2 24.0 2 8.7 0.4 4.7 4 1 1 5 5 5 0 zinc-finger-containing domain XPA_N PF01286.18 KFM79326.1 - 0.17 11.9 33.6 9.2 6.4 0.3 9.0 9 0 0 9 9 9 0 XPA protein N-terminal CpXC PF14353.6 KFM79326.1 - 0.23 11.5 31.1 12 6.0 0.2 8.2 2 2 3 6 6 6 0 CpXC protein C5HCH PF17982.1 KFM79326.1 - 0.46 10.7 44.9 2.5 8.3 1.2 8.8 6 2 3 9 9 9 0 NSD Cys-His rich domain GAGA PF09237.11 KFM79326.1 - 0.76 9.6 17.1 1 9.2 0.2 5.7 3 2 3 6 6 6 0 GAGA factor PHF5 PF03660.14 KFM79326.1 - 1.8 8.8 28.9 7.2 6.9 1.1 4.9 1 1 3 5 5 5 0 PHF5-like protein zf-FCS PF06467.14 KFM79326.1 - 4.3 7.4 33.5 18 5.4 0.3 8.4 3 2 5 9 9 9 0 MYM-type Zinc finger with FCS sequence motif FYVE PF01363.21 KFM79326.1 - 7.8 6.7 52.2 9 6.5 2.1 6.5 2 2 4 7 7 7 0 FYVE zinc finger Prok-RING_2 PF14445.6 KFM79326.1 - 7.9 6.7 24.8 59 3.9 0.2 7.5 9 0 0 9 9 8 0 Prokaryotic RING finger family 2 DUF1110 PF06533.12 KFM79327.1 - 0.095 12.7 0.1 0.095 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) C2-set_2 PF08205.12 KFM79328.1 - 1.3e-06 28.4 0.0 3.7e-06 26.9 0.0 1.7 1 1 1 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFM79328.1 - 3.6e-05 24.0 0.4 0.00018 21.8 0.0 2.2 1 1 1 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFM79328.1 - 0.00079 20.0 0.1 0.0026 18.3 0.0 1.8 1 1 1 2 2 2 1 Immunoglobulin domain Pex16 PF08610.10 KFM79328.1 - 0.037 13.2 0.2 0.049 12.8 0.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Sushi PF00084.20 KFM79328.1 - 0.043 14.4 0.0 0.21 12.2 0.0 2.1 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) zf-H2C2_2 PF13465.6 KFM79329.1 - 2.2e-58 192.2 68.8 1.4e-09 37.9 0.9 10.1 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79329.1 - 1.7e-36 122.7 91.0 3.8e-06 27.1 3.8 8.6 9 0 0 9 9 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79329.1 - 2.7e-23 80.6 78.4 0.00079 20.1 3.0 8.8 9 0 0 9 9 8 7 C2H2-type zinc finger zf-met PF12874.7 KFM79329.1 - 2.1e-17 62.8 56.4 0.008 16.5 1.3 8.5 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM79329.1 - 3.7e-16 58.9 42.3 0.021 15.1 0.2 8.4 7 1 1 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM79329.1 - 9.3e-14 51.0 50.3 0.0045 16.9 0.3 8.9 8 1 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM79329.1 - 0.00015 21.4 58.7 0.076 12.8 0.1 9.2 9 0 0 9 9 9 5 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 KFM79329.1 - 0.0015 19.2 23.2 1.6 9.5 1.2 4.2 2 1 2 4 4 4 3 zinc-ribbon family C1_1 PF00130.22 KFM79329.1 - 0.011 15.6 42.4 1.9 8.4 1.3 7.6 3 2 5 8 8 8 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_IE-1 PF05290.11 KFM79329.1 - 0.047 13.6 17.0 0.27 11.2 2.2 4.8 1 1 3 4 4 4 0 Baculovirus immediate-early protein (IE-0) ADK_lid PF05191.14 KFM79329.1 - 0.075 13.0 25.4 2.2 8.3 1.2 4.8 4 1 1 5 5 5 0 Adenylate kinase, active site lid zf-CHCC PF10276.9 KFM79329.1 - 0.081 13.0 11.4 27 4.9 0.0 6.4 7 0 0 7 7 7 0 Zinc-finger domain zf-RRPl_C4 PF17026.5 KFM79329.1 - 0.16 12.1 21.5 1.4 9.1 1.1 4.0 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_11 PF16622.5 KFM79329.1 - 0.18 11.6 0.4 0.18 11.6 0.4 7.3 7 0 0 7 7 7 0 zinc-finger C2H2-type GAGA PF09237.11 KFM79329.1 - 0.62 9.9 18.7 6.5 6.7 0.4 5.4 1 1 3 5 5 5 0 GAGA factor XPA_N PF01286.18 KFM79329.1 - 0.74 9.9 24.8 9.6 6.3 0.0 7.3 8 0 0 8 8 8 0 XPA protein N-terminal zf-C2H2_2 PF12756.7 KFM79329.1 - 0.92 9.9 51.0 3.2 8.2 1.5 6.4 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) PHF5 PF03660.14 KFM79329.1 - 1.3 9.3 21.7 1.9 8.7 1.1 4.2 1 1 3 4 4 4 0 PHF5-like protein zf-Paramyx-P PF13008.7 KFM79329.1 - 1.6 8.2 17.6 31 4.1 0.1 6.6 7 0 0 7 7 7 0 Zinc-binding domain of Paramyxoviridae V protein Laminin_N PF00055.17 KFM79329.1 - 3.4 7.2 22.0 2.5 7.6 2.6 4.4 1 1 3 4 4 4 0 Laminin N-terminal (Domain VI) zf-Sec23_Sec24 PF04810.15 KFM79329.1 - 4 7.6 22.2 26 5.0 0.0 7.4 8 0 0 8 8 8 0 Sec23/Sec24 zinc finger BolA PF01722.18 KFM79329.1 - 4.6 7.6 14.5 9.3 6.6 1.8 4.2 2 1 2 4 4 4 0 BolA-like protein zf-H2C2_2 PF13465.6 KFM79330.1 - 4.3e-85 276.7 76.8 3e-10 40.1 0.6 12.7 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79330.1 - 1.9e-59 194.9 113.0 2.9e-06 27.4 1.3 12.2 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79330.1 - 1.1e-31 106.8 100.3 0.0052 17.5 3.0 12.2 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM79330.1 - 2.1e-20 72.2 79.7 0.0016 18.4 0.4 12.4 12 0 0 12 12 12 10 C2H2-type zinc finger ADK_lid PF05191.14 KFM79330.1 - 7.5e-10 38.6 39.6 0.0044 17.0 1.8 8.1 5 2 3 9 9 9 7 Adenylate kinase, active site lid zf-C2H2_8 PF15909.5 KFM79330.1 - 6.9e-08 32.7 57.0 0.0045 17.2 6.0 6.5 1 1 6 7 7 7 5 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFM79330.1 - 1.7e-05 25.0 69.4 0.052 13.9 0.2 11.5 12 0 0 12 12 12 4 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM79330.1 - 0.00016 21.4 21.2 1 9.2 0.1 6.8 3 3 4 7 7 7 4 GAGA factor zf-RRPl_C4 PF17026.5 KFM79330.1 - 0.00021 21.3 46.0 0.0021 18.2 6.0 5.0 1 1 3 4 4 4 2 Putative ribonucleoprotein zinc-finger pf C4 type zf_UBZ PF18439.1 KFM79330.1 - 0.00032 20.2 55.6 0.96 9.1 0.5 10.6 10 0 0 10 10 10 4 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KFM79330.1 - 0.0005 20.8 47.7 0.064 14.0 5.0 6.3 1 1 7 8 8 8 5 zinc-ribbon family BBP1_N PF15271.6 KFM79330.1 - 0.014 16.2 0.2 66 4.3 0.1 3.8 1 1 0 3 3 3 0 Spindle pole body component BBP1, Mps2-binding protein zf-met PF12874.7 KFM79330.1 - 0.033 14.6 0.3 0.033 14.6 0.3 11.8 12 0 0 12 12 12 0 Zinc-finger of C2H2 type Sec31 PF11549.8 KFM79330.1 - 0.079 12.9 0.2 9.3 6.2 0.0 3.7 5 0 0 5 5 5 0 Protein transport protein SEC31 Zn-ribbon_8 PF09723.10 KFM79330.1 - 0.11 12.7 42.8 1.2 9.3 0.2 8.2 4 2 6 10 10 10 0 Zinc ribbon domain IGPD PF00475.18 KFM79330.1 - 0.22 11.8 15.6 0.22 11.8 1.2 5.0 3 2 1 4 4 4 0 Imidazoleglycerol-phosphate dehydratase C1_4 PF07975.12 KFM79330.1 - 1 9.6 59.5 0.98 9.7 7.9 8.0 3 2 7 10 10 10 0 TFIIH C1-like domain C1_1 PF00130.22 KFM79330.1 - 2.3 8.2 64.4 0.88 9.5 2.1 10.3 3 2 5 8 8 8 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 KFM79330.1 - 2.5 8.1 41.4 5.9 6.9 0.1 9.6 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFM79331.1 - 1.3e-126 407.9 121.8 8.1e-10 38.7 1.3 19.0 19 0 0 19 19 19 18 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79331.1 - 4.1e-84 272.6 168.7 2.6e-06 27.6 1.2 18.1 18 0 0 18 18 18 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79331.1 - 1.8e-60 196.3 156.3 0.00036 21.1 1.4 18.1 18 0 0 18 18 18 18 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM79331.1 - 1.2e-45 152.7 122.3 5.5e-06 26.2 0.8 18.9 18 1 0 18 18 18 17 C2H2-type zinc finger zf-met PF12874.7 KFM79331.1 - 1.2e-22 79.6 119.5 3.5e-06 27.2 2.2 17.1 17 0 0 17 17 17 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM79331.1 - 8.2e-21 73.8 108.2 0.00063 20.0 1.7 17.5 15 2 3 18 18 18 10 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM79331.1 - 2.4e-12 46.6 70.3 0.0031 17.4 1.3 11.8 8 3 4 12 12 12 8 Adenylate kinase, active site lid zf_UBZ PF18439.1 KFM79331.1 - 1.6e-09 37.1 80.0 0.86 9.3 0.1 17.0 18 0 0 18 18 18 8 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM79331.1 - 7.1e-06 25.8 70.8 0.16 11.9 0.1 16.2 17 0 0 17 17 17 5 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 KFM79331.1 - 9.5e-05 22.4 63.0 0.16 12.1 1.4 11.3 3 3 10 14 14 14 7 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM79331.1 - 0.00027 21.6 73.9 0.21 12.3 1.7 9.1 2 2 8 10 10 10 6 zinc-ribbon family SKA2 PF16740.5 KFM79331.1 - 0.0012 18.6 0.1 15 5.4 0.1 5.2 6 0 0 6 6 6 0 Spindle and kinetochore-associated protein 2 C1_1 PF00130.22 KFM79331.1 - 0.0018 18.1 95.3 4.1 7.4 0.6 15.8 2 1 12 14 14 14 3 Phorbol esters/diacylglycerol binding domain (C1 domain) BBP1_N PF15271.6 KFM79331.1 - 0.0026 18.6 0.0 18 6.1 0.0 3.9 3 1 1 4 4 4 0 Spindle pole body component BBP1, Mps2-binding protein zf-C2H2_2 PF12756.7 KFM79331.1 - 2.5 8.5 103.2 0.15 12.4 7.7 11.0 1 1 8 9 9 8 0 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM79331.1 - 3.9 7.6 66.0 0.67 10.1 2.0 7.0 1 1 4 7 7 7 0 Putative ribonucleoprotein zinc-finger pf C4 type Pyr_redox_2 PF07992.14 KFM79332.1 - 9.8e-68 228.5 3.5 5.3e-66 222.8 2.7 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFM79332.1 - 3.3e-40 136.8 0.8 2.5e-39 134.0 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFM79332.1 - 7.1e-18 64.9 4.2 6e-15 55.6 0.5 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFM79332.1 - 6.5e-10 38.9 0.1 1.9e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFM79332.1 - 1.1e-09 38.0 1.6 1.1e-08 34.7 1.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM79332.1 - 1.6e-09 37.4 0.5 1.8e-07 30.6 0.5 2.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFM79332.1 - 6.1e-07 29.6 2.7 0.00012 22.2 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFM79332.1 - 3.1e-06 26.7 2.9 0.12 11.6 0.1 3.2 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 KFM79332.1 - 9.4e-06 24.9 5.1 9.4e-06 24.9 5.1 2.5 1 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KFM79332.1 - 2e-05 23.5 7.1 0.00053 18.8 0.3 3.3 3 1 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KFM79332.1 - 0.00026 20.4 0.4 0.12 11.7 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KFM79332.1 - 0.00034 19.9 0.6 0.0023 17.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 KFM79332.1 - 0.042 13.4 0.8 5.2 6.6 0.0 3.2 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.6 KFM79332.1 - 0.084 12.0 1.1 2.7 7.0 0.1 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) XFP_C PF09363.10 KFM79332.1 - 0.13 11.8 0.1 3.1 7.2 0.0 2.5 3 0 0 3 3 3 0 XFP C-terminal domain DAO PF01266.24 KFM79332.1 - 0.47 10.0 10.0 2.4 7.7 0.1 3.6 2 1 2 4 4 4 0 FAD dependent oxidoreductase Rab5ip PF07019.12 KFM79334.1 - 1.6e-17 63.8 8.8 2.1e-17 63.4 8.8 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF4199 PF13858.6 KFM79334.1 - 0.089 13.2 5.4 0.13 12.7 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) LIM PF00412.22 KFM79335.1 - 1.8e-10 40.9 7.4 2.2e-10 40.6 7.4 1.0 1 0 0 1 1 1 1 LIM domain C1_1 PF00130.22 KFM79335.1 - 0.05 13.5 7.8 0.12 12.3 7.8 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFM79335.1 - 0.079 12.6 7.1 1.7 8.3 0.9 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Ribosomal_L37e PF01907.19 KFM79335.1 - 0.08 13.1 6.3 0.9 9.8 0.3 2.1 1 1 1 2 2 2 0 Ribosomal protein L37e TNFR_c6 PF00020.18 KFM79335.1 - 0.3 11.5 10.5 0.25 11.8 1.9 2.2 1 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region OrfB_Zn_ribbon PF07282.11 KFM79335.1 - 0.77 9.7 6.3 1.4 8.9 6.3 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Glyco_transf_8 PF01501.20 KFM79336.1 - 4.5e-17 62.4 0.5 7.4e-17 61.7 0.4 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFM79336.1 - 1e-06 28.4 1.4 1.6e-06 27.8 1.4 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Nucleotid_trans PF03407.16 KFM79336.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase bZIP_2 PF07716.15 KFM79336.1 - 0.36 10.9 3.8 0.74 9.9 3.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Glyco_transf_49 PF13896.6 KFM79337.1 - 2.6e-08 33.6 0.0 2.9e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.6 KFM79338.1 - 8.4e-36 124.0 0.4 9.1e-36 123.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.6 KFM79339.1 - 4.7e-25 88.6 0.0 7e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Nup54 PF13874.6 KFM79340.1 - 1.3e-42 145.2 2.0 1.3e-42 145.2 2.0 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 KFM79340.1 - 7.8e-17 60.9 2.3 7.8e-17 60.9 2.3 2.5 3 0 0 3 3 3 1 Nup54 C-terminal interacting domain Lact-deh-memb PF09330.11 KFM79340.1 - 0.0044 16.4 1.2 0.029 13.7 1.1 1.9 2 0 0 2 2 2 1 D-lactate dehydrogenase, membrane binding VirD1 PF07328.11 KFM79340.1 - 0.029 14.4 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 Nucleoporin_FG2 PF15967.5 KFM79340.1 - 2 6.8 36.6 10 4.5 35.8 1.9 1 1 0 1 1 1 0 Nucleoporin FG repeated region WD40 PF00400.32 KFM79341.1 - 5.5e-18 65.0 4.1 2e-05 25.3 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM79341.1 - 0.00037 20.7 0.1 0.67 10.3 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM79341.1 - 0.039 12.6 0.3 3.1 6.3 0.0 2.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF4186 PF13811.6 KFM79341.1 - 0.97 9.5 3.6 0.64 10.1 0.7 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4186) WD40 PF00400.32 KFM79342.1 - 2e-06 28.4 0.0 0.00045 21.0 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat VWC PF00093.18 KFM79343.1 - 1.1e-06 28.8 32.9 0.00052 20.3 13.2 2.4 2 0 0 2 2 2 2 von Willebrand factor type C domain VWC PF00093.18 KFM79344.1 - 0.00062 20.0 9.7 0.001 19.3 9.7 1.4 1 0 0 1 1 1 1 von Willebrand factor type C domain TILa PF12714.7 KFM79344.1 - 0.00076 19.4 4.1 0.0017 18.3 4.1 1.5 1 0 0 1 1 1 1 TILa domain Mucin PF01456.17 KFM79344.1 - 0.0067 16.4 5.6 0.0067 16.4 5.6 7.7 5 2 0 5 5 5 1 Mucin-like glycoprotein CFC PF09443.10 KFM79344.1 - 0.13 12.1 4.3 0.25 11.2 4.3 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) VWC PF00093.18 KFM79345.1 - 0.001 19.3 11.6 0.001 19.3 11.6 2.3 2 0 0 2 2 2 2 von Willebrand factor type C domain CFC PF09443.10 KFM79345.1 - 4.1 7.3 12.6 7.7 6.5 1.2 2.9 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Myosin_head PF00063.21 KFM79346.1 - 2.5e-128 429.2 0.0 2.5e-127 425.9 0.0 2.4 1 1 0 1 1 1 1 Myosin head (motor domain) PDZ PF00595.24 KFM79346.1 - 2.3e-08 34.3 0.0 7.1e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM79346.1 - 2.6e-07 30.4 0.0 1e-06 28.5 0.0 2.1 1 0 0 1 1 1 1 PDZ domain AAA_16 PF13191.6 KFM79346.1 - 0.0018 18.7 0.1 0.0057 17.1 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KFM79346.1 - 0.0044 16.8 0.2 0.011 15.5 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFM79346.1 - 0.0055 17.0 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFM79346.1 - 0.02 14.4 0.1 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IQ PF00612.27 KFM79346.1 - 0.049 13.4 8.0 0.12 12.2 0.3 3.0 3 0 0 3 3 3 0 IQ calmodulin-binding motif RsgA_GTPase PF03193.16 KFM79346.1 - 0.056 13.3 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase PDZ_2 PF13180.6 KFM79346.1 - 0.061 13.7 0.1 0.37 11.2 0.0 2.4 2 0 0 2 2 2 0 PDZ domain T2SSE PF00437.20 KFM79346.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4887 PF16228.5 KFM79346.1 - 2.4 8.3 17.7 5.6 7.1 17.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) TSP_1 PF00090.19 KFM79347.1 - 2.1e-35 120.7 82.6 1.7e-12 47.3 8.3 6.5 6 1 0 6 6 6 5 Thrombospondin type 1 domain Sema PF01403.19 KFM79348.1 - 8.5e-119 397.1 0.2 1e-118 396.8 0.2 1.1 1 0 0 1 1 1 1 Sema domain CBM_6 PF03422.15 KFM79349.1 - 0.032 14.5 1.3 0.074 13.4 1.3 1.6 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) RRM_7 PF16367.5 KFM79351.1 - 4e-24 84.6 0.0 4.4e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif CEBP_ZZ PF16366.5 KFM79352.1 - 1.8e-21 76.1 6.1 2.4e-21 75.7 6.1 1.2 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 KFM79352.1 - 0.24 11.6 8.8 0.56 10.4 8.8 1.6 1 1 0 1 1 1 0 B-box zinc finger Peptidase_M16_M PF16187.5 KFM79353.1 - 5.7e-39 134.1 1.7 9.7e-39 133.3 0.4 2.0 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KFM79353.1 - 1.6e-08 34.8 0.1 1.1e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 KFM79354.1 - 4.6e-39 134.4 0.1 5.8e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KFM79354.1 - 9.1e-09 35.6 0.0 4.9e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Dimer_Tnp_hAT PF05699.14 KFM79355.1 - 0.037 13.8 0.0 0.065 13.0 0.0 1.5 1 1 0 1 1 1 0 hAT family C-terminal dimerisation region ThiF PF00899.21 KFM79356.1 - 2.1e-101 338.4 0.0 5.9e-62 209.2 0.0 2.1 2 0 0 2 2 2 2 ThiF family E1_FCCH PF16190.5 KFM79356.1 - 9.7e-34 115.4 0.5 2.1e-33 114.3 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KFM79356.1 - 1.3e-27 95.7 0.4 3.6e-27 94.4 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle UBA_e1_thiolCys PF10585.9 KFM79356.1 - 1.3e-08 35.1 0.1 2.7e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 KFM79356.1 - 0.012 15.7 0.6 0.95 9.5 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 KFM79357.1 - 2.4e-53 181.7 0.0 2.5e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site DNA_methylase PF00145.17 KFM79357.1 - 0.001 18.5 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Ribosomal_L13 PF00572.18 KFM79358.1 - 1.3e-32 112.7 0.0 1.7e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 LSM PF01423.22 KFM79359.1 - 1.8e-19 69.2 0.3 2.2e-19 68.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain Tetraspanin PF00335.20 KFM79360.1 - 5.9e-52 176.7 9.4 6.6e-52 176.5 9.4 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF334 PF03904.13 KFM79360.1 - 0.31 10.6 0.5 8.1 5.9 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF334) FA_desaturase PF00487.24 KFM79360.1 - 0.51 10.1 2.1 1.8 8.3 1.7 1.9 1 1 1 2 2 2 0 Fatty acid desaturase ASC PF00858.24 KFM79361.1 - 2.7e-10 39.8 0.4 3e-10 39.6 0.4 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 KFM79362.1 - 1.5e-05 24.2 0.7 1.7e-05 24.0 0.7 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 KFM79363.1 - 0.00017 20.7 0.4 0.0002 20.5 0.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel LPAM_1 PF08139.12 KFM79364.1 - 0.079 13.5 1.8 0.47 11.1 0.0 2.7 3 0 0 3 3 3 0 Prokaryotic membrane lipoprotein lipid attachment site Keratin_2_head PF16208.5 KFM79364.1 - 5.8 7.0 27.0 7.9 6.6 27.0 1.1 1 0 0 1 1 1 0 Keratin type II head SecG PF03840.14 KFM79365.1 - 0.085 13.0 0.4 0.085 13.0 0.4 1.6 2 0 0 2 2 2 0 Preprotein translocase SecG subunit DCX PF03607.17 KFM79366.1 - 0.00053 20.0 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Doublecortin PEP-utilizers_C PF02896.18 KFM79366.1 - 0.14 11.2 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain ArsC PF03960.15 KFM79367.1 - 0.11 12.5 0.2 0.39 10.8 0.1 1.9 2 0 0 2 2 2 0 ArsC family Peptidase_C48 PF02902.19 KFM79370.1 - 1.3e-21 77.4 0.1 1.8e-21 77.0 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SRF-TF PF00319.18 KFM79371.1 - 9.5e-25 85.8 0.5 1.5e-24 85.2 0.5 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 KFM79371.1 - 1.9e-12 47.0 0.3 1.9e-12 47.0 0.3 2.2 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat GHD PF17834.1 KFM79371.1 - 0.05 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase Chordopox_A33R PF05966.12 KFM79372.1 - 0.32 10.3 2.5 0.31 10.3 2.5 1.0 1 0 0 1 1 1 0 Chordopoxvirus A33R protein SecG PF03840.14 KFM79375.1 - 0.32 11.1 2.5 0.47 10.6 2.5 1.3 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Chorion_3 PF05387.11 KFM79376.1 - 1.7 8.2 5.2 1.8 8.1 5.2 1.1 1 0 0 1 1 1 0 Chorion family 3 CTP_transf_like PF01467.26 KFM79378.1 - 2.3e-31 108.9 0.0 3.7e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Tim29 PF10171.9 KFM79378.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 Transposase_1 PF01359.18 KFM79379.1 - 2.8e-11 43.1 0.2 3.3e-11 42.9 0.2 1.1 1 0 0 1 1 1 1 Transposase (partial DDE domain) zf-CCHC_4 PF14392.6 KFM79380.1 - 0.071 12.9 0.6 0.14 12.0 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Noelin-1 PF12308.8 KFM79381.1 - 0.073 13.1 0.3 0.22 11.5 0.3 1.7 1 1 1 2 2 2 0 Neurogenesis glycoprotein RRM_1 PF00076.22 KFM79382.1 - 0.023 14.5 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFM79382.1 - 0.027 14.6 1.4 0.064 13.4 0.7 1.9 2 0 0 2 2 2 0 Zinc knuckle NTPase_1 PF03266.15 KFM79385.1 - 1.6e-09 37.9 0.1 1.7e-09 37.8 0.1 1.0 1 0 0 1 1 1 1 NTPase NTPase_1 PF03266.15 KFM79386.1 - 3.5e-29 101.9 0.1 4.1e-29 101.6 0.1 1.0 1 0 0 1 1 1 1 NTPase AAA_19 PF13245.6 KFM79386.1 - 4.1e-05 24.0 0.0 4.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM79386.1 - 8.1e-05 22.9 0.0 8.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM79386.1 - 9.4e-05 22.4 0.1 0.00012 22.1 0.1 1.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KFM79386.1 - 0.00012 22.6 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM79386.1 - 0.0002 21.8 0.0 0.0002 21.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KFM79386.1 - 0.0002 21.9 0.0 0.00025 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFM79386.1 - 0.00036 20.5 0.0 0.00036 20.5 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KFM79386.1 - 0.00037 20.0 0.1 0.00047 19.7 0.1 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 KFM79386.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFM79386.1 - 0.0029 17.4 0.2 0.0046 16.7 0.2 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KFM79386.1 - 0.004 16.9 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KFM79386.1 - 0.0042 17.0 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KFM79386.1 - 0.0051 16.2 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KFM79386.1 - 0.0058 17.0 0.0 0.0065 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFM79386.1 - 0.006 16.6 0.0 0.0078 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KFM79386.1 - 0.0064 16.2 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KFM79386.1 - 0.008 16.3 0.0 0.009 16.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KFM79386.1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 KFM79386.1 - 0.01 15.6 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM79386.1 - 0.024 14.3 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 KFM79386.1 - 0.025 14.6 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KFM79386.1 - 0.025 14.4 0.0 0.027 14.3 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFM79386.1 - 0.027 14.7 0.2 0.04 14.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM79386.1 - 0.028 14.3 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KFM79386.1 - 0.032 14.6 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase MeaB PF03308.16 KFM79386.1 - 0.042 12.8 0.0 0.082 11.9 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 KFM79386.1 - 0.047 13.9 0.1 0.053 13.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KFM79386.1 - 0.08 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MCM PF00493.23 KFM79386.1 - 0.08 12.0 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain DUF853 PF05872.12 KFM79386.1 - 0.086 11.4 0.0 0.086 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) KAP_NTPase PF07693.14 KFM79386.1 - 0.093 11.9 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 KFM79386.1 - 0.099 13.2 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KFM79386.1 - 0.1 12.2 0.1 0.16 11.5 0.1 1.3 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KFM79386.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KFM79386.1 - 0.1 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 KFM79386.1 - 0.1 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 KFM79386.1 - 0.12 12.1 0.3 0.16 11.7 0.3 1.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Bac_DNA_binding PF00216.21 KFM79386.1 - 0.12 12.5 0.3 0.18 12.1 0.3 1.2 1 0 0 1 1 1 0 Bacterial DNA-binding protein NB-ARC PF00931.22 KFM79386.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.2 1 1 0 1 1 1 0 NB-ARC domain TniB PF05621.11 KFM79386.1 - 0.21 11.0 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Pkinase PF00069.25 KFM79387.1 - 2.1e-75 253.5 0.0 2.3e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM79387.1 - 2.1e-36 125.5 0.0 2.7e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM79387.1 - 3.3e-05 23.0 0.2 0.00011 21.3 0.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM79387.1 - 3.7e-05 23.2 0.2 7.4e-05 22.2 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM79387.1 - 6.3e-05 22.4 0.2 0.00021 20.7 0.1 1.8 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KFM79387.1 - 0.0021 18.0 0.1 0.0057 16.6 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFM79387.1 - 0.031 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 KFM79387.1 - 0.06 13.0 0.2 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LRR_4 PF12799.7 KFM79388.1 - 2e-21 75.7 16.4 6e-07 29.7 1.1 4.6 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM79388.1 - 2.8e-21 75.1 36.6 1.4e-09 37.6 5.1 4.3 1 1 4 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 KFM79388.1 - 4.4e-09 35.6 9.8 0.21 12.3 0.1 6.3 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.6 KFM79388.1 - 5.5e-05 22.7 8.1 0.0017 17.9 2.5 2.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 KFM79388.1 - 0.00024 21.0 6.5 0.0038 17.2 3.3 2.6 1 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFM79388.1 - 0.0025 17.7 18.3 0.22 11.7 0.4 5.9 6 0 0 6 6 6 1 Leucine Rich repeat Ion_trans_2 PF07885.16 KFM79389.1 - 1.1e-33 115.0 19.4 2e-18 66.1 5.5 2.6 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFM79389.1 - 3e-07 29.9 6.5 0.0068 15.7 0.0 2.3 1 1 1 2 2 2 2 Ion transport protein Lig_chan PF00060.26 KFM79389.1 - 0.0055 16.6 1.0 0.27 11.0 0.0 2.8 3 0 0 3 3 3 1 Ligand-gated ion channel DUF4477 PF14780.6 KFM79389.1 - 0.082 12.5 0.7 0.13 11.9 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Oxidored_q2 PF00420.24 KFM79389.1 - 0.42 10.3 5.3 0.51 10.0 0.7 2.7 2 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2207 PF09972.9 KFM79389.1 - 0.45 9.2 4.8 0.63 8.7 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 KFM79389.1 - 0.53 10.6 6.5 6.6 7.1 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Translin PF01997.16 KFM79390.1 - 5.7e-55 186.5 0.4 7.2e-55 186.1 0.4 1.1 1 0 0 1 1 1 1 Translin family FAD_binding_3 PF01494.19 KFM79392.1 - 0.0045 16.3 0.0 0.0045 16.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KFM79392.1 - 0.071 12.1 0.0 0.082 11.9 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_3 PF01494.19 KFM79393.1 - 2.9e-09 36.6 0.0 3.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KFM79393.1 - 0.00092 18.3 0.0 0.0025 16.9 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase DUF1361 PF07099.11 KFM79393.1 - 0.061 13.3 0.9 0.18 11.8 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1361) P_C10 PF14974.6 KFM79395.1 - 1.9e-39 133.9 0.1 2.2e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 Protein C10 HOK_GEF PF01848.16 KFM79396.1 - 2.3 7.7 12.1 5 6.6 12.1 1.5 1 0 0 1 1 1 0 Hok/gef family DUF3377 PF11857.8 KFM79396.1 - 2.5 8.1 5.2 2.5 8.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) EphA2_TM PF14575.6 KFM79396.1 - 4 8.4 4.8 20 6.1 0.1 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ARL6IP6 PF15062.6 KFM79398.1 - 2.3e-10 40.4 1.9 3.4e-10 39.9 1.7 1.4 1 1 0 1 1 1 1 Haemopoietic lineage transmembrane helix DUF2417 PF10329.9 KFM79398.1 - 0.24 10.8 3.6 0.28 10.6 3.6 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Esterase PF00756.20 KFM79399.1 - 8.5e-65 218.9 0.0 9.8e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KFM79399.1 - 3e-07 29.6 0.0 4.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KFM79399.1 - 8.3e-06 25.4 0.1 1.1e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFM79399.1 - 0.0007 18.9 0.0 0.00083 18.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KFM79399.1 - 0.00096 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.11 KFM79399.1 - 0.0053 15.8 0.0 0.41 9.6 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Esterase_phd PF10503.9 KFM79399.1 - 0.0092 15.5 0.0 0.048 13.2 0.0 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase DLH PF01738.18 KFM79399.1 - 0.061 12.9 0.0 0.54 9.8 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF2048 PF09752.9 KFM79399.1 - 0.073 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 PGAP1 PF07819.13 KFM79399.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 KFM79399.1 - 0.15 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KFM79399.1 - 0.17 12.4 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Tubulin PF00091.25 KFM79400.1 - 1.1e-67 228.1 0.0 1.9e-67 227.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM79400.1 - 7.4e-48 161.9 0.1 1.3e-47 161.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFM79400.1 - 0.0021 18.3 0.0 0.0077 16.5 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFM79400.1 - 0.003 16.8 0.0 0.0063 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Hrs_helical PF12210.8 KFM79400.1 - 0.084 13.4 1.4 0.19 12.3 1.4 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Pox_TAA1 PF03295.14 KFM79402.1 - 4.4 7.3 13.1 56 3.7 0.0 4.6 2 1 2 4 4 4 0 Poxvirus trans-activator protein A1 C-terminal ZIP4_domain PF18292.1 KFM79405.1 - 0.012 15.6 0.2 0.019 14.9 0.1 1.5 1 1 0 1 1 1 0 Zinc transporter ZIP4 domain Phage_int_SAM_5 PF13102.6 KFM79405.1 - 0.028 14.8 0.8 0.06 13.7 0.8 1.5 1 0 0 1 1 1 0 Phage integrase SAM-like domain LOR PF04525.12 KFM79405.1 - 0.03 13.9 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 LURP-one-related 7tm_1 PF00001.21 KFM79406.1 - 2.3e-18 66.5 11.3 3.7e-18 65.8 11.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NAGLU PF05089.12 KFM79407.1 - 3.5e-136 453.6 6.8 4.5e-136 453.2 6.8 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_N PF12971.7 KFM79407.1 - 3.6e-27 94.0 0.1 1.4e-26 92.1 0.0 2.1 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain NAGLU_C PF12972.7 KFM79407.1 - 7.2e-07 29.0 0.5 1.1e-06 28.4 0.5 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_C PF12972.7 KFM79408.1 - 8e-43 146.9 0.0 8.8e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain LZ3wCH PF18517.1 KFM79408.1 - 0.055 13.6 0.5 0.1 12.7 0.5 1.4 1 0 0 1 1 1 0 Leucine zipper with capping helix domain Aha1_N PF09229.11 KFM79409.1 - 2e-35 122.0 1.3 3.6e-35 121.2 1.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFM79409.1 - 5.8e-17 62.1 0.8 1.2e-16 61.1 0.2 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein ELK PF03789.13 KFM79409.1 - 0.059 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 ELK domain DNA_ligase_A_M PF01068.21 KFM79410.1 - 2.5e-56 190.6 0.0 4.8e-56 189.6 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFM79410.1 - 2.2e-33 116.0 0.1 7.7e-33 114.3 0.1 2.0 1 0 0 1 1 1 1 DNA ligase N terminus LIG3_BRCT PF16759.5 KFM79410.1 - 2.8e-22 78.8 0.0 8.5e-22 77.3 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain zf-PARP PF00645.18 KFM79410.1 - 1.8e-20 73.6 0.2 5.2e-20 72.1 0.2 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DNA_ligase_A_C PF04679.15 KFM79410.1 - 1.4e-14 54.4 0.0 4e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KFM79410.1 - 1.4e-08 35.0 0.1 4.7e-08 33.3 0.1 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 KFM79410.1 - 2e-07 31.5 0.1 4.2e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 KFM79410.1 - 0.00049 20.0 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Ras PF00071.22 KFM79411.1 - 1.1e-56 191.0 0.1 1.2e-56 190.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM79411.1 - 1.4e-20 73.7 0.0 2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM79411.1 - 2.3e-11 43.5 0.0 2.6e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFM79411.1 - 1.1e-05 25.4 0.3 0.023 14.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFM79411.1 - 0.00012 21.6 0.4 0.00053 19.6 0.1 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM79411.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KFM79411.1 - 0.013 14.7 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 KFM79411.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KFM79411.1 - 0.058 12.9 0.4 0.18 11.3 0.4 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ParA PF10609.9 KFM79411.1 - 0.11 11.9 0.5 0.15 11.5 0.3 1.4 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase zf-C2H2_4 PF13894.6 KFM79413.1 - 1.4e-20 72.2 31.9 0.00023 21.7 0.8 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM79413.1 - 4.8e-19 67.7 34.0 7.7e-06 26.1 1.4 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM79413.1 - 2.3e-15 56.2 33.4 0.00013 22.2 1.0 5.8 6 1 0 6 6 5 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM79413.1 - 9.3e-10 38.5 24.5 0.0077 16.5 0.2 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM79413.1 - 1.3e-06 28.3 31.4 0.00064 19.6 0.3 5.6 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM79413.1 - 4.8e-05 23.6 29.1 0.088 13.1 2.1 5.0 1 1 4 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFM79413.1 - 0.00086 19.7 24.6 0.42 11.1 1.7 4.7 1 1 4 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 KFM79413.1 - 0.0012 19.5 11.1 0.009 16.7 3.3 3.3 1 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KFM79413.1 - 0.0021 18.4 26.2 0.0029 18.0 0.2 5.1 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-BED PF02892.15 KFM79413.1 - 0.015 15.3 1.0 0.015 15.3 1.0 4.1 3 2 2 5 5 5 0 BED zinc finger DUF629 PF04780.12 KFM79413.1 - 0.017 13.6 2.5 0.017 13.6 2.5 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF629) zf-C2H2_aberr PF17017.5 KFM79413.1 - 0.023 14.8 2.2 0.023 14.8 2.2 2.6 2 1 1 3 3 3 0 Aberrant zinc-finger E6 PF00518.17 KFM79413.1 - 0.038 14.4 10.7 0.18 12.3 4.6 3.2 1 1 2 3 3 3 0 Early Protein (E6) Zn_ribbon_SprT PF17283.2 KFM79413.1 - 0.047 13.6 5.4 0.047 13.6 5.4 3.4 3 1 1 4 4 3 0 SprT-like zinc ribbon domain PyrI_C PF02748.15 KFM79413.1 - 0.05 13.5 12.2 2.4 8.1 0.4 4.2 4 1 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KFM79413.1 - 0.079 13.7 17.0 0.5 11.2 1.3 3.2 1 1 2 3 3 3 0 zinc-ribbon family Baculo_IE-1 PF05290.11 KFM79413.1 - 0.13 12.2 6.5 15 5.5 0.7 3.4 2 2 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Zn-ribbon_8 PF09723.10 KFM79413.1 - 0.3 11.2 18.2 0.14 12.3 1.1 4.2 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFM79413.1 - 0.6 9.9 24.5 3 7.7 0.9 4.8 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFM79413.1 - 0.87 9.5 10.5 0.86 9.5 0.1 3.8 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) Mut7-C PF01927.16 KFM79413.1 - 0.9 9.6 13.7 0.23 11.6 1.2 2.7 1 1 1 3 3 3 0 Mut7-C RNAse domain zinc_ribbon_4 PF13717.6 KFM79413.1 - 0.92 9.5 14.0 2.8 7.9 0.0 4.7 5 0 0 5 5 5 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 KFM79413.1 - 1.5 8.9 15.2 13 6.0 2.3 4.8 4 1 0 4 4 4 0 Sec23/Sec24 zinc finger zinc_ribbon_12 PF11331.8 KFM79413.1 - 1.6 8.6 14.0 2.8 7.8 1.7 3.9 3 2 1 4 4 4 0 Probable zinc-ribbon domain zf-C2HC_2 PF13913.6 KFM79413.1 - 2.4 8.2 14.6 2.8 7.9 0.4 4.3 4 0 0 4 4 3 0 zinc-finger of a C2HC-type DUF2225 PF09986.9 KFM79413.1 - 2.6 7.7 14.7 0.69 9.6 0.5 3.4 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) FYDLN_acid PF09538.10 KFM79413.1 - 5.9 7.6 7.6 43 4.9 1.0 3.6 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) Elf1 PF05129.13 KFM79413.1 - 7.3 6.7 21.7 0.095 12.8 1.9 3.4 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Spt46 PF17734.1 KFM79413.1 - 8.2 6.2 13.2 0.49 10.2 1.4 3.5 1 1 3 4 4 4 0 Spermatogenesis-associated protein 46 zf-C2H2_4 PF13894.6 KFM79414.1 - 2.5e-49 161.6 224.2 0.00087 19.9 0.2 28.8 30 0 0 30 30 30 24 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM79414.1 - 2e-44 147.6 226.4 0.00012 22.3 0.5 28.7 30 0 0 30 30 30 24 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM79414.1 - 8.2e-22 76.6 196.4 1.5e-08 34.7 0.6 27.4 30 0 0 30 30 30 12 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM79414.1 - 2.9e-18 65.7 163.2 0.0048 17.2 0.3 25.3 27 0 0 27 27 27 15 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM79414.1 - 1.2e-11 44.3 154.8 0.0027 17.7 0.1 22.4 23 1 1 24 24 24 11 C2H2-type zinc finger zf-met PF12874.7 KFM79414.1 - 1.2e-07 31.8 155.8 0.0022 18.4 0.5 23.8 26 0 0 26 26 26 10 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM79414.1 - 0.00067 19.9 1.2 0.00067 19.9 1.2 17.1 12 5 8 20 20 20 8 Drought induced 19 protein (Di19), zinc-binding zf-LYAR PF08790.11 KFM79414.1 - 0.026 14.4 1.0 0.026 14.4 1.0 17.6 22 0 0 22 22 22 0 LYAR-type C2HC zinc finger zf-C2H2_3rep PF18868.1 KFM79414.1 - 0.24 12.1 0.1 0.24 12.1 0.1 13.6 3 1 10 15 15 15 0 Zinc finger C2H2-type, 3 repeats Med8 PF10232.9 KFM79415.1 - 0.0044 16.6 1.5 0.0066 16.1 0.1 1.9 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription complex subunit 8 HEAT_2 PF13646.6 KFM79415.1 - 0.011 16.1 0.6 5.6 7.4 0.2 3.2 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 KFM79415.1 - 1.4 9.4 3.5 12 6.5 0.5 4.2 5 0 0 5 5 5 0 HEAT repeat Aminotran_1_2 PF00155.21 KFM79416.1 - 3.5e-32 112.0 0.0 3.9e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFM79416.1 - 0.0033 16.8 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 KFM79416.1 - 0.017 13.9 0.0 0.045 12.5 0.0 1.6 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase DUF3692 PF12469.8 KFM79416.1 - 0.19 12.0 0.0 0.4 10.9 0.0 1.7 2 0 0 2 2 2 0 CRISPR-associated protein Keratin_assoc PF09775.9 KFM79417.1 - 4.1e-53 178.5 9.6 4.4e-53 178.4 9.6 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 ThrE PF06738.12 KFM79417.1 - 0.037 13.4 7.0 0.047 13.0 7.0 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter PNTB PF02233.16 KFM79417.1 - 0.37 9.7 6.5 0.42 9.5 6.5 1.0 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit SK_channel PF03530.14 KFM79417.1 - 0.4 10.7 7.8 0.18 11.8 4.8 1.8 1 1 1 2 2 2 0 Calcium-activated SK potassium channel YibE_F PF07907.11 KFM79417.1 - 2 7.9 17.1 2 7.8 6.2 2.1 1 1 1 2 2 2 0 YibE/F-like protein His_Phos_1 PF00300.22 KFM79418.1 - 1.7e-22 80.1 0.1 1.7e-20 73.6 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Chibby PF14645.6 KFM79419.1 - 3.9e-20 72.4 3.0 4.6e-20 72.2 3.0 1.0 1 0 0 1 1 1 1 Chibby family YabA PF06156.13 KFM79419.1 - 0.69 10.6 4.7 0.55 10.9 2.2 1.8 1 1 1 2 2 2 0 Initiation control protein YabA CCDC85 PF10226.9 KFM79420.1 - 9.9e-67 224.4 20.0 1.2e-66 224.1 16.6 2.3 2 1 0 2 2 2 1 CCDC85 family AMH_N PF04709.12 KFM79420.1 - 0.014 14.4 0.2 0.014 14.4 0.2 2.2 1 1 1 2 2 2 0 Anti-Mullerian hormone, N terminal region FliD_N PF02465.18 KFM79420.1 - 0.075 13.7 2.9 13 6.6 0.4 2.9 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Nudix_N_2 PF14803.6 KFM79420.1 - 0.33 10.9 3.5 0.25 11.3 0.4 2.5 2 0 0 2 2 2 0 Nudix N-terminal WXG100 PF06013.12 KFM79420.1 - 0.34 11.2 5.6 5.4 7.3 0.4 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF5082 PF16888.5 KFM79420.1 - 0.37 11.1 13.9 0.28 11.5 2.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) TSC22 PF01166.18 KFM79420.1 - 0.5 10.7 18.6 5.4 7.4 2.4 4.5 3 1 1 4 4 4 0 TSC-22/dip/bun family Occludin_ELL PF07303.13 KFM79420.1 - 0.63 10.8 9.7 7.9 7.3 3.7 2.7 2 0 0 2 2 2 0 Occludin homology domain Shugoshin_N PF07558.11 KFM79420.1 - 1.6 8.7 13.2 0.22 11.4 4.7 3.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Exonuc_VII_L PF02601.15 KFM79420.1 - 2.2 7.8 13.3 1.8 8.1 2.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit YfcL PF08891.11 KFM79420.1 - 3.6 8.0 7.8 0.47 10.8 0.4 3.2 4 0 0 4 4 4 0 YfcL protein DivIC PF04977.15 KFM79420.1 - 5.3 6.9 14.7 8.3 6.3 3.3 3.6 2 1 1 3 3 3 0 Septum formation initiator Arm-DNA-bind_5 PF17293.2 KFM79420.1 - 7.4 7.1 11.0 32 5.0 0.1 3.5 2 1 0 2 2 2 0 Arm DNA-binding domain Methyltransf_25 PF13649.6 KFM79421.1 - 1.2e-11 45.2 0.0 2.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM79421.1 - 2.8e-09 37.5 0.0 6.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFM79421.1 - 6.2e-09 35.7 0.1 9.2e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFM79421.1 - 2.1e-08 34.1 0.2 3.6e-08 33.4 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM79421.1 - 1.7e-07 31.3 0.0 3.1e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFM79421.1 - 4.4e-07 29.5 0.1 6.4e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KFM79421.1 - 0.00012 21.1 0.1 0.00018 20.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KFM79421.1 - 0.00017 21.2 0.2 0.00028 20.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KFM79421.1 - 0.00026 20.9 0.3 0.00044 20.2 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM79421.1 - 0.00061 20.5 0.0 0.001 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFM79421.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KFM79421.1 - 0.067 12.7 0.3 0.11 11.9 0.3 1.4 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.16 KFM79421.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_32 PF13679.6 KFM79421.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KFM79421.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PRMT5 PF05185.16 KFM79421.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 KFM79421.1 - 0.14 13.2 0.0 0.26 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Tetraspanin PF00335.20 KFM79422.1 - 1.5e-17 64.1 6.1 1.7e-17 63.9 6.1 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF981 PF06168.11 KFM79422.1 - 0.014 15.3 0.4 0.019 14.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF1461 PF07314.11 KFM79422.1 - 0.046 13.6 1.3 0.056 13.4 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF2214 PF09980.9 KFM79422.1 - 0.1 12.4 1.5 0.12 12.1 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) DUF2892 PF11127.8 KFM79422.1 - 0.1 12.6 8.9 0.1 12.6 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF5402 PF17393.2 KFM79422.1 - 0.15 12.0 0.3 0.15 12.0 0.3 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5402) FYVE PF01363.21 KFM79423.1 - 1.4e-15 57.2 6.5 1.4e-15 57.2 6.5 4.9 4 1 0 4 4 4 1 FYVE zinc finger GBP PF02263.19 KFM79423.1 - 0.0021 17.4 0.1 0.0057 15.9 0.0 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain ELMO_CED12 PF04727.13 KFM79425.1 - 4.1e-29 101.9 0.0 6.7e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family IL31 PF15209.6 KFM79426.1 - 0.0065 16.2 0.2 0.007 16.1 0.2 1.1 1 0 0 1 1 1 1 Interleukin 31 Complex1_LYR_2 PF13233.6 KFM79427.1 - 0.0023 18.6 0.3 0.0032 18.2 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PDEase_I PF00233.19 KFM79429.1 - 2.1e-85 286.3 7.3 3e-85 285.7 7.3 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SR-25 PF10500.9 KFM79429.1 - 0.48 10.0 11.0 0.76 9.3 11.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PDEase_I_N PF08499.12 KFM79430.1 - 2e-16 59.5 1.2 3.8e-16 58.7 1.2 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF5544 PF17698.1 KFM79430.1 - 0.034 14.2 0.2 0.056 13.6 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5544) Ebp2 PF05890.12 KFM79431.1 - 1.6e-43 149.2 41.1 2.9e-43 148.4 41.1 1.4 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 PAF-AH_p_II PF03403.13 KFM79431.1 - 0.22 10.0 7.0 0.32 9.5 7.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II ALMT PF11744.8 KFM79431.1 - 0.9 8.3 11.1 1 8.1 11.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA PF00004.29 KFM79432.1 - 3.9e-40 137.4 0.0 7.2e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM79432.1 - 5.7e-09 35.6 0.1 1.1e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFM79432.1 - 2.2e-05 24.8 0.0 0.0036 17.6 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KFM79432.1 - 0.00043 20.3 0.1 0.0016 18.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM79432.1 - 0.00073 20.0 0.3 0.015 15.7 0.1 2.4 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KFM79432.1 - 0.0013 18.5 0.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFM79432.1 - 0.0024 18.0 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFM79432.1 - 0.0038 16.4 0.0 0.0064 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFM79432.1 - 0.0074 16.8 0.0 0.018 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFM79432.1 - 0.0074 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFM79432.1 - 0.0089 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFM79432.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFM79432.1 - 0.04 13.3 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KFM79432.1 - 0.042 13.6 0.1 0.4 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KFM79432.1 - 0.046 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KFM79432.1 - 0.049 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KFM79432.1 - 0.055 12.7 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KFM79432.1 - 0.078 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KFM79432.1 - 0.078 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFM79432.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM79432.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain CBM_14 PF01607.24 KFM79433.1 - 8.1e-10 38.7 6.4 8.1e-10 38.7 6.4 2.4 3 0 0 3 3 3 1 Chitin binding Peritrophin-A domain Polysacc_deac_1 PF01522.21 KFM79433.1 - 0.00017 21.5 0.0 0.00059 19.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Myosin_head PF00063.21 KFM79433.1 - 0.2 9.8 0.1 0.28 9.4 0.1 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) ubiquitin PF00240.23 KFM79434.1 - 2.3e-08 33.7 0.1 3.3e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFM79434.1 - 1.5e-05 24.8 0.1 5.4e-05 22.9 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RP1-2 PF12042.8 KFM79435.1 - 1.1e-06 28.6 35.7 1.6e-06 28.1 0.2 5.0 4 1 0 4 4 4 4 Tubuliform egg casing silk strands structural domain MspA PF09203.11 KFM79435.1 - 0.52 10.1 20.9 0.69 9.7 7.8 3.6 2 1 0 2 2 2 0 MspA MyTH4 PF00784.17 KFM79437.1 - 1.1e-11 45.2 0.1 3.2e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 MyTH4 domain RNase_H PF00075.24 KFM79439.1 - 5e-80 266.7 0.7 6.6e-39 133.4 0.0 2.3 2 0 0 2 2 2 2 RNase H Cauli_VI PF01693.16 KFM79439.1 - 9.1e-54 179.5 16.1 6e-19 68.1 0.6 3.5 3 0 0 3 3 3 3 Caulimovirus viroplasmin RVT_3 PF13456.6 KFM79439.1 - 3.2e-09 36.7 0.0 0.0035 17.1 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase-like EcoRII-N PF09217.10 KFM79439.1 - 0.017 14.9 0.4 0.4 10.4 0.4 2.2 2 0 0 2 2 2 0 Restriction endonuclease EcoRII, N-terminal PADR1 PF08063.12 KFM79439.1 - 0.057 13.2 2.0 0.39 10.5 0.3 2.8 2 0 0 2 2 2 0 PADR1 (NUC008) domain ETC_C1_NDUFA4 PF04800.12 KFM79439.1 - 0.13 12.6 0.6 28 5.1 0.1 2.6 2 0 0 2 2 2 0 ETC complex I subunit conserved region CNH PF00780.22 KFM79441.1 - 3.9e-60 203.8 0.0 5.5e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFM79441.1 - 5e-50 170.3 0.0 9.1e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM79441.1 - 1.1e-37 129.7 0.0 1.7e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM79441.1 - 2.9e-05 23.0 0.0 2.9e-05 23.0 0.0 2.6 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFM79441.1 - 0.0017 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM79441.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFM79441.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 EBV-NA1 PF02905.14 KFM79441.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Pyridoxal_deC PF00282.19 KFM79442.1 - 1.3e-93 313.7 0.0 1.6e-93 313.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFM79442.1 - 4.7e-06 26.1 0.0 7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFM79442.1 - 8.8e-05 21.6 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta-lactamase PF00144.24 KFM79443.1 - 3.6e-07 29.7 0.0 6.2e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase RVT_1 PF00078.27 KFM79444.1 - 0.0026 17.3 0.0 0.0029 17.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2726 PF10881.8 KFM79444.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Glyco_hydro_38N PF01074.22 KFM79445.1 - 1.5e-98 329.8 7.1 2e-98 329.3 7.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 KFM79445.1 - 2.1e-23 82.3 0.0 8.3e-23 80.4 0.0 2.1 1 0 0 1 1 1 1 Alpha mannosidase middle domain Sugarporin_N PF11471.8 KFM79445.1 - 0.019 14.9 0.5 0.019 14.9 0.5 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Glyco_hydro_38C PF07748.13 KFM79446.1 - 4.6e-20 72.6 0.1 5.8e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Citrate_synt PF00285.21 KFM79448.1 - 4.5e-104 348.4 0.0 5.3e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain zf-H2C2_2 PF13465.6 KFM79450.1 - 1.4e-83 271.9 104.2 6.3e-09 35.9 0.1 13.9 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79450.1 - 1.2e-57 189.2 131.1 6.6e-06 26.3 0.6 14.1 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79450.1 - 4.2e-42 139.1 119.0 0.00029 21.4 0.6 14.1 14 0 0 14 14 14 13 C2H2-type zinc finger zf-met PF12874.7 KFM79450.1 - 3.2e-31 106.8 104.5 0.0024 18.2 1.9 13.6 13 0 0 13 13 13 13 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM79450.1 - 1.7e-22 78.9 99.4 0.0008 19.3 1.6 13.9 14 0 0 14 14 14 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM79450.1 - 6.1e-20 71.0 79.9 0.089 13.1 0.3 13.4 13 0 0 13 13 13 10 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM79450.1 - 3.1e-16 58.8 77.7 0.015 15.1 1.3 14.1 14 0 0 14 14 14 9 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM79450.1 - 3.6e-12 45.8 97.3 0.019 14.7 6.0 13.7 14 0 0 14 14 14 10 zinc-finger C2H2-type zf-RRPl_C4 PF17026.5 KFM79450.1 - 1.3e-09 38.1 64.5 0.0046 17.0 13.2 5.7 1 1 5 6 6 6 6 Putative ribonucleoprotein zinc-finger pf C4 type zf-Sec23_Sec24 PF04810.15 KFM79450.1 - 2.5e-07 30.6 44.4 0.12 12.4 0.1 11.9 7 4 5 12 12 12 2 Sec23/Sec24 zinc finger GAGA PF09237.11 KFM79450.1 - 5.5e-06 26.1 21.2 1.5 8.7 0.1 9.0 2 2 8 10 10 10 3 GAGA factor Tox-HNH-HHH PF15637.6 KFM79450.1 - 0.0002 21.5 2.9 3.3 7.9 0.1 4.4 2 1 2 5 5 5 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif BolA PF01722.18 KFM79450.1 - 0.006 16.8 28.2 0.73 10.1 0.2 7.8 2 2 6 8 8 8 2 BolA-like protein zf-C2H2_2 PF12756.7 KFM79450.1 - 0.023 15.0 102.2 3.4 8.1 2.4 12.8 1 1 12 13 13 13 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM79450.1 - 0.11 12.1 0.1 0.11 12.1 0.1 11.3 6 5 7 13 13 13 0 MYST family zinc finger domain DUF2256 PF10013.9 KFM79450.1 - 0.3 11.3 59.8 0.74 10.0 0.1 12.1 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFM79450.1 - 0.79 9.8 55.8 0.35 10.9 2.5 9.1 5 3 5 10 10 10 0 Adenylate kinase, active site lid zf-C2H2_9 PF16293.5 KFM79450.1 - 1.7 8.6 61.9 4.8 7.1 0.1 12.5 5 4 8 13 13 13 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM79450.1 - 7.3 7.4 59.8 7.3 7.4 2.4 6.9 1 1 6 7 7 7 0 zinc-ribbon family FYVE PF01363.21 KFM79450.1 - 9.4 6.5 77.9 21 5.4 13.4 7.2 1 1 5 6 6 5 0 FYVE zinc finger PseudoU_synth_1 PF01416.20 KFM79451.1 - 0.027 14.9 0.0 0.037 14.5 0.0 1.2 1 0 0 1 1 1 0 tRNA pseudouridine synthase Peptidase_M13 PF01431.21 KFM79452.1 - 2e-09 37.3 0.0 2e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 TPR_19 PF14559.6 KFM79454.1 - 6.7e-17 61.8 7.3 2.2e-07 31.2 0.2 3.1 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM79454.1 - 1.9e-14 52.6 0.2 0.0002 21.3 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM79454.1 - 7.5e-14 50.7 5.3 0.0043 17.1 0.1 4.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM79454.1 - 8.7e-13 47.5 2.2 0.009 15.8 0.0 4.4 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFM79454.1 - 1.1e-12 48.4 2.0 0.0018 18.9 0.4 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM79454.1 - 6.1e-12 45.7 4.0 0.0012 19.1 0.1 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM79454.1 - 2.3e-08 34.2 5.6 0.19 12.7 0.1 4.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFM79454.1 - 3.9e-06 27.2 0.1 0.025 15.2 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM79454.1 - 4.4e-06 26.3 1.9 0.059 13.4 0.1 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM79454.1 - 7.1e-05 22.3 1.9 0.00041 19.8 0.5 2.0 1 1 1 2 2 2 1 MalT-like TPR region TPR_17 PF13431.6 KFM79454.1 - 9.2e-05 22.6 3.8 3 8.4 0.0 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 KFM79454.1 - 0.00013 21.6 0.4 0.06 12.8 0.0 2.3 3 0 0 3 3 3 2 Est1 DNA/RNA binding domain TPR_11 PF13414.6 KFM79454.1 - 0.0002 21.0 0.9 0.53 10.0 0.0 3.4 3 1 1 4 4 4 2 TPR repeat TPR_9 PF13371.6 KFM79454.1 - 0.0004 20.5 3.0 0.0021 18.2 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM79454.1 - 0.00042 20.5 1.3 0.028 14.6 0.1 2.4 2 1 1 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFM79454.1 - 0.0005 19.8 2.7 4.9 7.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KFM79454.1 - 0.00074 19.0 0.4 0.28 10.6 0.0 2.1 2 0 0 2 2 2 2 Coatomer epsilon subunit Sel1 PF08238.12 KFM79454.1 - 0.039 14.6 1.4 0.43 11.3 0.0 3.2 3 0 0 3 3 3 0 Sel1 repeat TPR_4 PF07721.14 KFM79454.1 - 1.3 9.8 0.0 1.3 9.8 0.0 3.2 4 0 0 4 4 2 0 Tetratricopeptide repeat WD40_4 PF16300.5 KFM79455.1 - 1.1e-23 82.8 0.1 1.6e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Type of WD40 repeat Glyco_transf_92 PF01697.27 KFM79456.1 - 8.8e-13 48.5 0.8 8.8e-13 48.5 0.8 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFM79456.1 - 0.042 14.4 0.2 0.081 13.4 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF1459 PF07312.11 KFM79458.1 - 0.25 11.6 8.2 0.28 11.4 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) ABC_tran PF00005.27 KFM79460.1 - 1.5e-35 122.7 0.0 1.6e-17 64.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KFM79460.1 - 2.9e-13 49.4 6.2 7.3e-13 48.1 6.2 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 KFM79460.1 - 8.5e-10 38.9 2.7 0.16 11.7 1.0 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM79460.1 - 9.4e-10 38.3 3.9 0.016 14.6 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 KFM79460.1 - 2.8e-08 33.2 3.8 2.8e-08 33.2 3.8 3.2 4 0 0 4 4 4 1 4Fe-4S binding domain AAA_16 PF13191.6 KFM79460.1 - 3.1e-06 27.7 0.0 0.12 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KFM79460.1 - 4.2e-06 27.2 0.0 0.12 12.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.7 KFM79460.1 - 1.8e-05 24.6 3.3 1.8e-05 24.6 3.3 2.9 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.6 KFM79460.1 - 4.4e-05 23.4 0.0 0.21 11.3 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 KFM79460.1 - 6.3e-05 23.0 0.1 0.031 14.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 KFM79460.1 - 0.00014 21.8 0.0 0.52 10.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFM79460.1 - 0.00019 21.7 0.0 0.056 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFM79460.1 - 0.00051 19.7 0.2 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_21 PF14697.6 KFM79460.1 - 0.00053 20.1 13.1 0.0014 18.7 13.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KFM79460.1 - 0.00061 19.7 1.0 0.00061 19.7 1.0 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 KFM79460.1 - 0.00079 19.5 15.4 0.0022 18.0 1.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_7 PF12775.7 KFM79460.1 - 0.00085 18.9 0.0 0.02 14.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region SRP54 PF00448.22 KFM79460.1 - 0.00093 18.9 1.9 0.17 11.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KFM79460.1 - 0.0011 19.1 0.0 0.64 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KFM79460.1 - 0.0012 18.6 0.0 0.41 10.3 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase Rad17 PF03215.15 KFM79460.1 - 0.0021 18.0 0.0 0.28 11.1 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_7 PF12838.7 KFM79460.1 - 0.0021 18.6 1.3 0.0021 18.6 1.3 2.9 2 1 2 4 4 4 2 4Fe-4S dicluster domain TsaE PF02367.17 KFM79460.1 - 0.0024 17.9 0.0 0.087 12.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFM79460.1 - 0.0026 18.1 0.0 2.8 8.4 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KFM79460.1 - 0.0034 17.1 2.0 0.23 11.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 KFM79460.1 - 0.0035 17.5 13.0 0.0086 16.2 13.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFM79460.1 - 0.01 16.7 0.2 0.01 16.7 0.2 2.8 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain VirE PF05272.11 KFM79460.1 - 0.015 15.1 0.0 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_5 PF07728.14 KFM79460.1 - 0.015 15.3 0.2 2.7 8.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KFM79460.1 - 0.018 15.6 4.8 0.15 12.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFM79460.1 - 0.04 13.6 0.4 2.6 7.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFM79460.1 - 0.051 13.8 0.3 12 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFM79460.1 - 0.057 13.5 0.0 16 5.6 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KFM79460.1 - 0.059 13.4 0.3 12 6.0 0.0 2.9 2 1 1 3 3 2 0 AAA domain NB-ARC PF00931.22 KFM79460.1 - 0.074 12.2 0.0 3.7 6.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KFM79460.1 - 0.11 13.0 0.0 3.7 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.7 KFM79460.1 - 0.13 12.8 14.9 0.14 12.7 3.0 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain TniB PF05621.11 KFM79460.1 - 0.15 11.5 0.1 1.8 7.9 0.0 2.5 3 0 0 3 3 3 0 Bacterial TniB protein Roc PF08477.13 KFM79460.1 - 0.29 11.4 0.7 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KFM79460.1 - 0.31 10.9 4.1 7.3 6.5 0.0 3.5 4 0 0 4 4 4 0 NTPase Fer4_8 PF13183.6 KFM79460.1 - 0.91 10.0 10.3 0.18 12.3 0.9 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KFM79460.1 - 5.7 7.6 12.3 0.11 13.0 1.5 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain PAH PF02671.21 KFM79461.1 - 1e-17 64.0 0.2 2.5e-09 37.1 0.4 2.8 2 0 0 2 2 2 2 Paired amphipathic helix repeat DUF2972 PF11186.8 KFM79461.1 - 0.62 9.9 7.0 0.76 9.7 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2972) Sin3_corepress PF08295.12 KFM79462.1 - 0.0033 17.5 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 KFM79463.1 - 6.4e-50 170.5 5.9 6.4e-50 170.5 5.9 3.4 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KFM79463.1 - 8.7e-11 41.8 1.0 4.7e-10 39.4 1.0 2.4 1 0 0 1 1 1 1 Sin3 family co-repressor RP1-2 PF12042.8 KFM79464.1 - 2.1e-13 50.5 5.5 5.8e-08 32.8 0.1 4.0 4 0 0 4 4 4 3 Tubuliform egg casing silk strands structural domain Spidroin_N PF16763.5 KFM79464.1 - 3.6e-12 46.4 3.9 1.5e-10 41.2 0.2 3.1 2 0 0 2 2 2 2 Major ampullate spidroin 1, spider silk protein 1, N-term Chitin_bind_4 PF00379.23 KFM79465.1 - 1.7e-08 34.8 1.7 2.8e-08 34.2 1.7 1.4 1 0 0 1 1 1 1 Insect cuticle protein GCV_T PF01571.21 KFM79467.1 - 3.8e-50 170.7 0.0 4.6e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SoxG PF04268.12 KFM79467.1 - 0.0098 16.0 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family DUF1455 PF07306.11 KFM79467.1 - 0.061 13.3 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) DUF3399 PF11879.8 KFM79469.1 - 8.3e-13 48.6 2.8 1.3e-12 48.0 2.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3399) Ion_trans PF00520.31 KFM79469.1 - 0.002 17.4 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein IL23 PF16649.5 KFM79470.1 - 0.069 13.2 0.0 0.069 13.2 0.0 1.1 1 0 0 1 1 1 0 Interleukin 23 subunit alpha Pkinase_Tyr PF07714.17 KFM79472.1 - 3.5e-15 56.0 0.0 4.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM79472.1 - 2.6e-12 46.7 0.1 4.7e-12 45.8 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM79473.1 - 3.1e-25 88.9 2.3 3.4e-25 88.8 0.2 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFM79473.1 - 6e-18 65.2 0.0 1.6e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.30 KFM79473.1 - 1.7e-13 50.8 0.6 3.6e-13 49.8 0.6 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM79473.1 - 7e-12 45.3 0.4 1.5e-11 44.2 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) YEATS PF03366.16 KFM79473.1 - 0.0015 18.5 0.1 0.54 10.3 0.1 2.7 2 0 0 2 2 2 2 YEATS family DUF3552 PF12072.8 KFM79473.1 - 0.032 13.6 6.8 0.056 12.9 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Med9 PF07544.13 KFM79473.1 - 0.53 10.4 4.2 1.3 9.2 4.2 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 RPN6_N PF18055.1 KFM79474.1 - 7.9e-35 119.7 1.4 1.5e-34 118.9 0.3 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KFM79474.1 - 4.7e-18 65.6 2.0 6.9e-18 65.1 0.4 2.2 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KFM79474.1 - 2.7e-13 49.4 0.6 5.9e-13 48.3 0.6 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain SbsC_C PF18058.1 KFM79474.1 - 0.053 13.7 1.6 0.078 13.2 0.2 2.0 2 0 0 2 2 2 0 SbsC C-terminal domain TPR_21 PF09976.9 KFM79474.1 - 0.056 13.1 2.1 0.16 11.7 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain PEP-utilisers_N PF05524.13 KFM79474.1 - 0.064 13.4 0.1 0.23 11.6 0.1 2.0 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TPR_MalT PF17874.1 KFM79474.1 - 0.083 12.3 2.2 0.13 11.6 1.2 1.8 2 0 0 2 2 2 0 MalT-like TPR region DDRGK PF09756.9 KFM79474.1 - 0.086 12.4 2.8 0.12 11.9 0.4 2.1 2 0 0 2 2 2 0 DDRGK domain Vps39_1 PF10366.9 KFM79474.1 - 1.2 9.4 4.7 2.2 8.6 0.3 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 Strep_SA_rep PF06696.11 KFM79474.1 - 1.5 9.0 6.2 0.75 9.9 0.3 3.2 3 0 0 3 3 3 0 Streptococcal surface antigen repeat TPR_12 PF13424.6 KFM79474.1 - 7.9 6.9 12.8 1.1 9.6 2.2 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 KFM79475.1 - 2.6e-15 56.5 0.1 3.5e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM79475.1 - 2.3e-13 50.0 0.0 3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 KFM79475.1 - 3.8e-12 46.3 0.8 4.5e-11 42.8 0.8 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 KFM79475.1 - 4.4e-11 42.7 0.1 6.5e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFM79475.1 - 2.8e-10 40.8 0.0 5.5e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM79475.1 - 4e-08 33.1 0.0 5.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 KFM79475.1 - 1.6e-07 32.0 0.0 3.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM79475.1 - 3.1e-06 27.7 0.0 7.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM79475.1 - 0.00014 21.3 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KFM79475.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KFM79475.1 - 0.003 17.5 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFM79475.1 - 0.0036 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF43 PF01861.16 KFM79475.1 - 0.0041 16.4 0.0 0.074 12.3 0.0 2.0 1 1 1 2 2 2 1 Branched-chain polyamine synthase A C-terminal domain N6_Mtase PF02384.16 KFM79475.1 - 0.0045 16.3 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_4 PF02390.17 KFM79475.1 - 0.005 16.3 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 KFM79475.1 - 0.039 13.2 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltrans_SAM PF10672.9 KFM79475.1 - 0.076 12.2 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase CDK5_activator PF03261.15 KFM79476.1 - 5e-100 335.6 22.3 9e-99 331.4 22.3 2.0 1 1 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein Cyt_bd_oxida_I PF01654.17 KFM79477.1 - 0.011 14.4 0.6 0.014 14.1 0.6 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I UCH PF00443.29 KFM79478.1 - 1.3e-49 169.0 0.2 3.3e-49 167.7 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM79478.1 - 8.4e-38 130.7 0.2 8.4e-38 130.7 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 KFM79478.1 - 3.1e-07 30.8 0.2 0.13 12.7 0.0 4.1 4 0 0 4 4 4 2 Ubiquitin-like domain USP7_ICP0_bdg PF12436.8 KFM79478.1 - 0.00028 20.3 0.3 0.35 10.2 0.1 3.3 3 0 0 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 ubiquitin PF00240.23 KFM79478.1 - 0.00083 19.1 0.2 4.6 7.1 0.0 4.2 4 0 0 4 4 4 2 Ubiquitin family UN_NPL4 PF11543.8 KFM79478.1 - 0.0056 17.1 0.1 52 4.4 0.0 3.9 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 RA PF00788.23 KFM79478.1 - 0.012 16.3 1.2 0.17 12.6 0.0 3.0 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain 7tm_1 PF00001.21 KFM79479.1 - 2.5e-38 131.9 10.4 3.3e-38 131.5 10.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFM79479.1 - 6.7e-07 28.9 7.5 1.1e-06 28.3 7.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFM79479.1 - 0.023 14.0 9.0 0.14 11.5 9.0 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Sugar_tr PF00083.24 KFM79480.1 - 1.5e-21 76.8 2.5 2.1e-21 76.4 2.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM79480.1 - 2.9e-08 33.0 7.6 2.9e-08 33.0 7.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Tropomyosin_1 PF12718.7 KFM79480.1 - 0.3 11.2 1.8 2.9 8.1 1.9 1.9 2 0 0 2 2 2 0 Tropomyosin like Mito_carr PF00153.27 KFM79483.1 - 1.3e-67 223.8 0.2 2.2e-24 85.2 0.0 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KFM79483.1 - 1.4e-16 58.7 6.2 4.3e-07 29.0 0.0 5.4 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 KFM79483.1 - 2.6e-16 59.8 7.3 1.4e-06 28.7 0.5 4.3 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFM79483.1 - 7.7e-14 50.4 9.1 4.3e-06 26.2 0.0 6.0 7 0 0 7 7 7 3 EF-hand domain EF-hand_5 PF13202.6 KFM79483.1 - 8.1e-12 44.1 4.8 2.1e-05 23.8 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFM79483.1 - 4.5e-09 36.0 5.5 0.022 14.6 0.1 4.7 5 0 0 5 5 5 2 EF-hand domain pair MIF4G_like_2 PF09090.11 KFM79484.1 - 1.3e-82 277.3 6.6 1.7e-82 276.9 6.6 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KFM79484.1 - 4.9e-40 137.4 2.8 8.9e-40 136.5 0.6 2.4 2 1 0 2 2 2 1 MIF4G like MIF4G PF02854.19 KFM79484.1 - 0.0057 16.3 3.4 0.0067 16.1 0.0 2.7 3 1 1 4 4 4 1 MIF4G domain Pox_Ag35 PF03286.14 KFM79484.1 - 0.015 15.1 0.2 0.024 14.5 0.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein tRNA_bind_2 PF13725.6 KFM79484.1 - 0.021 14.5 2.3 0.088 12.5 2.6 1.8 2 0 0 2 2 2 0 Possible tRNA binding domain Seryl_tRNA_N PF02403.22 KFM79484.1 - 0.094 12.9 2.7 0.2 11.9 2.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3195 PF11424.8 KFM79484.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) INCA1 PF15142.6 KFM79484.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 INCA1 Cob_adeno_trans PF01923.18 KFM79484.1 - 0.6 10.2 3.2 1.6 8.8 1.6 2.6 2 1 0 2 2 2 0 Cobalamin adenosyltransferase DUF3381 PF11861.8 KFM79484.1 - 2.6 7.8 8.3 3.8 7.3 7.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) MIF4G PF02854.19 KFM79485.1 - 1.2e-07 31.6 0.0 1.5e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain DMPK_coil PF08826.10 KFM79486.1 - 0.033 14.3 3.5 7.4 6.8 2.7 2.6 2 1 0 2 2 2 0 DMPK coiled coil domain like RCC1 PF00415.18 KFM79487.1 - 9.1e-22 77.4 0.4 2.6e-11 44.0 0.1 3.1 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM79487.1 - 1.9e-13 49.8 0.1 1.2e-06 28.2 0.0 3.5 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.22 KFM79488.1 - 1.1e-12 47.6 0.0 1.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KFM79488.1 - 1.1e-06 28.5 1.8 3.3e-06 27.0 1.8 1.9 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KFM79488.1 - 5.4e-06 27.1 0.0 1e-05 26.2 0.0 1.4 1 0 0 1 1 1 1 Torus domain RRM_occluded PF16842.5 KFM79488.1 - 3.7e-05 23.5 0.0 0.0001 22.1 0.0 1.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFM79488.1 - 0.0011 19.0 0.2 0.0022 18.0 0.0 1.5 2 0 0 2 2 2 1 RNA binding motif zf-CCCH PF00642.24 KFM79488.1 - 0.0023 17.8 1.8 0.0023 17.8 1.8 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFM79488.1 - 0.0067 16.2 1.8 0.015 15.1 1.8 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KFM79488.1 - 0.0087 16.3 0.5 0.023 14.9 0.2 1.9 2 0 0 2 2 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFM79488.1 - 0.014 15.9 0.5 0.014 15.9 0.5 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Nup35_RRM_2 PF14605.6 KFM79488.1 - 0.019 14.9 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zinc-ribbons_6 PF07191.12 KFM79488.1 - 8.6 6.4 11.4 31 4.7 11.4 2.0 1 1 0 1 1 1 0 zinc-ribbons Cu2_monoox_C PF03712.15 KFM79489.1 - 2.9e-14 52.9 5.4 3.6e-14 52.6 5.4 1.0 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KFM79490.1 - 8e-23 81.1 0.0 9.1e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Orai-1 PF07856.12 KFM79491.1 - 2.7e-44 150.9 11.7 3.1e-44 150.7 11.7 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity TRP PF06011.12 KFM79491.1 - 0.16 10.6 9.0 0.19 10.5 9.0 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel SAMP PF05924.11 KFM79492.1 - 1.4e-11 43.3 38.9 0.0078 15.5 1.5 9.2 9 0 0 9 9 9 7 SAMP Motif APC_r PF05923.12 KFM79492.1 - 0.071 12.9 0.2 0.35 10.6 0.0 2.4 2 0 0 2 2 2 0 APC repeat APC_15aa PF05972.11 KFM79494.1 - 3.3e-05 23.9 0.5 7.1e-05 22.8 0.5 1.6 1 0 0 1 1 1 1 APC 15 residue motif APC_r PF05923.12 KFM79494.1 - 0.0031 17.2 0.1 0.0031 17.2 0.1 2.8 3 0 0 3 3 3 1 APC repeat DUF1062 PF06353.12 KFM79495.1 - 0.0017 19.2 0.5 0.0028 18.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1062) Borrelia_P83 PF05262.11 KFM79496.1 - 0.13 10.7 1.2 0.098 11.1 0.1 1.4 2 0 0 2 2 2 0 Borrelia P83/100 protein Ank_4 PF13637.6 KFM79498.1 - 9.7e-46 153.6 14.0 4.1e-11 43.2 0.1 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM79498.1 - 2.9e-44 149.5 13.9 1.4e-19 70.4 1.5 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFM79498.1 - 5e-40 134.2 17.9 2.1e-08 34.3 0.9 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFM79498.1 - 3.1e-35 119.8 13.5 9.4e-08 32.2 0.2 6.2 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM79498.1 - 2.2e-33 110.5 9.2 2.4e-06 27.4 0.1 7.1 7 0 0 7 7 7 6 Ankyrin repeat VWA_3_C PF18571.1 KFM79498.1 - 0.019 14.8 2.9 12 5.8 0.1 3.7 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain 3HCDH_RFF PF18321.1 KFM79498.1 - 0.087 13.3 0.4 0.087 13.3 0.4 2.0 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain PEGA PF08308.11 KFM79498.1 - 0.093 12.6 0.0 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 PEGA domain Imm_superinfect PF14373.6 KFM79498.1 - 0.2 11.6 1.3 18 5.4 0.0 3.8 5 0 0 5 5 5 0 Superinfection immunity protein TatD_DNase PF01026.21 KFM79501.1 - 6.7e-55 186.2 0.0 8.2e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase JAB PF01398.21 KFM79502.1 - 5.9e-24 84.3 0.1 1e-23 83.5 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFM79502.1 - 6e-16 58.9 0.7 9e-16 58.3 0.7 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KFM79502.1 - 0.011 15.8 0.3 0.026 14.6 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) W2 PF02020.18 KFM79503.1 - 2.9e-22 78.6 5.2 1e-21 76.8 3.9 2.6 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Nas2_N PF18265.1 KFM79504.1 - 2.5e-30 104.2 0.2 3.8e-30 103.6 0.2 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KFM79504.1 - 6.4e-08 32.3 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFM79504.1 - 9e-05 22.8 0.0 0.00013 22.3 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KFM79504.1 - 0.00014 22.1 0.0 0.00027 21.2 0.0 1.5 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM79504.1 - 0.00053 20.3 0.0 0.00081 19.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain zf-H2C2_2 PF13465.6 KFM79506.1 - 1.8e-125 404.3 132.7 2.2e-08 34.1 0.9 19.1 19 0 0 19 19 19 18 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79506.1 - 3.3e-86 279.2 170.1 2e-05 24.8 0.2 18.1 18 0 0 18 18 18 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79506.1 - 9.1e-57 184.8 153.2 0.00074 20.2 1.3 17.8 18 0 0 18 18 18 17 C2H2-type zinc finger zf-met PF12874.7 KFM79506.1 - 1.8e-49 164.8 158.6 0.00021 21.5 3.7 17.6 16 1 0 17 17 17 17 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM79506.1 - 4.1e-35 119.4 116.2 0.0017 18.6 0.3 17.3 17 0 0 17 17 17 17 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM79506.1 - 2.7e-22 78.2 122.3 0.051 13.6 0.2 17.8 17 0 0 17 17 17 15 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM79506.1 - 2.3e-20 72.0 108.6 0.068 12.9 0.5 18.1 18 0 0 18 18 18 12 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM79506.1 - 4.9e-16 58.5 77.7 0.2 11.7 0.2 17.4 7 5 11 18 18 18 8 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM79506.1 - 1.1e-14 53.8 70.4 1.2 9.1 0.1 17.3 17 0 0 17 17 17 5 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM79506.1 - 3.3e-09 36.8 83.7 0.091 12.9 5.0 7.7 1 1 7 8 8 8 7 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM79506.1 - 4.6e-09 36.2 58.5 15 5.8 0.1 17.1 17 0 0 17 17 17 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM79506.1 - 9.9e-06 25.6 87.7 7.3 6.8 0.3 16.8 17 0 0 17 17 17 1 DBF zinc finger BolA PF01722.18 KFM79506.1 - 6.3e-05 23.2 44.9 0.38 11.0 1.0 10.9 1 1 11 12 12 12 1 BolA-like protein IGPD PF00475.18 KFM79506.1 - 0.00096 19.5 35.5 1.4 9.2 0.4 9.3 2 1 3 10 10 10 2 Imidazoleglycerol-phosphate dehydratase Tox-HNH-HHH PF15637.6 KFM79506.1 - 0.0084 16.2 11.9 13 6.0 0.1 6.3 3 2 3 7 7 7 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif ATPgrasp_Ter PF15632.6 KFM79506.1 - 0.032 14.0 0.8 36 4.1 0.0 4.5 4 2 1 5 5 5 0 ATP-grasp in the biosynthetic pathway with Ter operon zf-CHCC PF10276.9 KFM79506.1 - 0.046 13.8 25.8 79 3.4 0.0 12.3 14 0 0 14 14 14 0 Zinc-finger domain zf-C2H2_9 PF16293.5 KFM79506.1 - 0.15 11.9 97.8 5.3 7.0 0.4 16.5 5 4 12 17 17 17 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM79506.1 - 0.21 12.3 84.5 1.9 9.3 1.8 9.2 1 1 8 10 10 10 0 zinc-ribbon family DUF1642 PF07852.11 KFM79506.1 - 0.27 11.8 13.5 0.075 13.6 0.8 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1642) Flag1_repress PF03614.13 KFM79506.1 - 8.9 6.1 17.4 5.4 6.8 0.6 4.9 1 1 6 7 7 7 0 Repressor of phase-1 flagellin Methyltransf_25 PF13649.6 KFM79508.1 - 2e-15 57.3 0.0 9.6e-15 55.1 0.0 2.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM79508.1 - 2e-15 57.0 0.0 2.9e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM79508.1 - 3.4e-12 46.8 0.0 9e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM79508.1 - 1.9e-10 40.7 0.0 3.9e-10 39.7 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM79508.1 - 1.9e-09 38.2 0.0 4.9e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM79508.1 - 0.00015 21.2 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 KFM79508.1 - 0.0015 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase FtsJ PF01728.19 KFM79508.1 - 0.007 16.5 0.0 0.0091 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.17 KFM79508.1 - 0.067 12.4 0.0 0.95 8.6 0.0 2.1 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Bin3 PF06859.12 KFM79508.1 - 0.068 13.8 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Amelogenin PF02948.15 KFM79509.1 - 0.98 10.0 12.2 2.5 8.7 3.0 2.0 1 1 1 2 2 2 0 Amelogenin Pkinase PF00069.25 KFM79511.1 - 6.2e-38 130.7 0.0 8.1e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM79511.1 - 2.3e-16 59.8 0.0 3.6e-16 59.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM79511.1 - 7.8e-05 22.1 0.4 0.00055 19.3 0.4 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM79511.1 - 0.00042 19.2 0.0 0.00061 18.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM79511.1 - 0.00065 18.7 0.9 0.00065 18.7 0.9 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KFM79511.1 - 0.042 13.2 0.2 0.074 12.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Imm31 PF15591.6 KFM79511.1 - 0.2 11.5 0.3 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Immunity protein 31 MRG PF05712.13 KFM79512.1 - 1.2e-47 161.7 1.7 2.1e-47 161.0 1.7 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KFM79512.1 - 1e-16 60.5 0.1 2.6e-16 59.3 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KFM79512.1 - 0.11 12.4 2.1 0.27 11.2 2.1 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Presenilin PF01080.17 KFM79512.1 - 0.12 11.1 2.3 0.16 10.7 2.3 1.1 1 0 0 1 1 1 0 Presenilin NHL PF01436.21 KFM79513.1 - 1.4e-20 72.2 12.1 6.5e-05 22.8 0.0 6.4 6 0 0 6 6 6 4 NHL repeat SBBP PF06739.11 KFM79513.1 - 1.9e-05 24.5 0.6 4.7 7.3 0.1 4.1 4 0 0 4 4 4 3 Beta-propeller repeat SGL PF08450.12 KFM79513.1 - 0.0003 20.4 0.2 0.073 12.6 0.1 3.4 1 1 1 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 KFM79513.1 - 0.00057 19.9 0.0 0.044 13.7 0.0 2.8 2 1 0 2 2 2 1 Esterase-like activity of phytase Lactonase PF10282.9 KFM79513.1 - 0.021 14.1 0.0 2.6 7.2 0.0 2.7 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller Ufd2P_core PF10408.9 KFM79515.1 - 1.1e-158 529.7 5.7 1.7e-158 529.1 5.7 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFM79515.1 - 1.2e-29 102.3 0.8 3.2e-29 100.9 0.8 1.8 1 0 0 1 1 1 1 U-box domain Sugar_tr PF00083.24 KFM79516.1 - 5.4e-76 256.3 25.4 6.6e-76 256.0 25.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM79516.1 - 6.9e-32 110.7 29.1 2.6e-30 105.5 27.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KFM79516.1 - 0.024 14.5 0.0 0.024 14.5 0.0 2.6 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sugar_tr PF00083.24 KFM79517.1 - 7.4e-74 249.2 26.3 8.9e-74 249.0 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM79517.1 - 6e-32 110.9 33.0 2.5e-31 108.9 28.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFM79518.1 - 0.0014 17.7 0.9 0.0016 17.4 0.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM79519.1 - 2.3e-63 214.6 27.1 2.6e-63 214.5 27.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM79519.1 - 6.9e-21 74.6 26.4 6.9e-21 74.6 26.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM79520.1 - 1e-68 232.3 34.1 1.3e-68 231.9 34.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM79520.1 - 3e-38 131.6 67.5 6.4e-32 110.8 38.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PAP2_3 PF14378.6 KFM79520.1 - 0.0086 15.8 0.0 0.0086 15.8 0.0 4.0 3 2 0 3 3 3 1 PAP2 superfamily TMEM192 PF14802.6 KFM79520.1 - 0.3 10.2 1.7 0.74 8.9 0.0 2.4 3 0 0 3 3 3 0 TMEM192 family Sugar_tr PF00083.24 KFM79521.1 - 4.4e-43 147.8 17.6 5.7e-43 147.4 17.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM79521.1 - 1.2e-14 54.0 16.9 1.5e-14 53.7 16.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CIMR PF00878.18 KFM79522.1 - 0.0015 18.6 1.4 0.024 14.7 0.4 2.3 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat AAA_26 PF13500.6 KFM79522.1 - 0.049 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain JIP_LZII PF16471.5 KFM79524.1 - 0.048 13.8 3.7 0.077 13.2 3.7 1.5 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Pox_A_type_inc PF04508.12 KFM79524.1 - 0.21 11.5 5.3 0.41 10.6 1.1 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat MbeD_MobD PF04899.12 KFM79525.1 - 2.8e-05 24.2 10.0 0.0016 18.5 0.6 3.3 3 0 0 3 3 3 2 MbeD/MobD like ATG16 PF08614.11 KFM79525.1 - 0.00069 19.9 21.3 0.046 14.0 11.3 2.2 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KFM79525.1 - 0.0045 16.8 17.2 0.0045 16.8 17.2 2.2 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 KFM79525.1 - 0.014 15.2 20.6 0.7 9.7 4.3 3.7 2 1 0 3 3 3 0 Septum formation initiator NYD-SP28_assoc PF14775.6 KFM79525.1 - 0.034 14.3 0.7 0.034 14.3 0.7 3.4 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF4665 PF15679.5 KFM79525.1 - 0.34 11.5 11.6 1.2 9.8 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4665) WXG100 PF06013.12 KFM79525.1 - 0.88 9.9 5.3 11 6.3 0.1 3.3 3 0 0 3 3 3 0 Proteins of 100 residues with WXG RBD-FIP PF09457.10 KFM79525.1 - 1.3 9.0 9.6 0.13 12.2 1.5 3.1 3 0 0 3 3 2 0 FIP domain LMBR1 PF04791.16 KFM79525.1 - 1.4 7.8 10.5 1.7 7.5 10.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 KFM79525.1 - 1.5 7.3 3.2 1.7 7.1 3.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2913 PF11140.8 KFM79525.1 - 2.1 8.1 13.5 5.6 6.6 1.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2913) DUF1492 PF07374.11 KFM79525.1 - 3.1 8.0 9.4 0.28 11.4 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) GAS PF13851.6 KFM79525.1 - 3.7 6.8 28.1 5.5 6.3 18.9 2.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-H PF05837.12 KFM79525.1 - 9.8 6.6 27.7 3.6 8.0 5.3 3.2 1 1 2 3 3 3 0 Centromere protein H (CENP-H) ATG16 PF08614.11 KFM79526.1 - 0.00024 21.4 74.9 0.036 14.3 11.4 4.2 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KFM79526.1 - 0.00053 19.7 80.5 0.19 11.3 14.4 4.9 1 1 3 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.6 KFM79526.1 - 0.00059 18.6 7.7 0.00059 18.6 7.7 3.0 1 1 2 3 3 3 2 AAA domain LRRFIP PF09738.9 KFM79526.1 - 0.0011 18.6 31.0 0.0011 18.6 31.0 3.8 1 1 2 3 3 2 1 LRRFIP family TMF_TATA_bd PF12325.8 KFM79526.1 - 0.002 18.3 16.8 0.002 18.3 16.8 5.4 1 1 4 5 5 5 2 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 KFM79526.1 - 0.002 17.1 39.8 0.002 17.1 39.8 3.0 1 1 2 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 KFM79526.1 - 0.0062 16.6 77.9 0.11 12.5 27.1 3.9 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein Cep57_MT_bd PF06657.13 KFM79526.1 - 0.0082 16.6 10.4 0.0082 16.6 10.4 6.1 2 2 3 5 5 4 2 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.11 KFM79526.1 - 0.024 13.5 77.5 0.029 13.3 27.6 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein CagA PF03507.13 KFM79526.1 - 0.17 11.8 7.3 0.14 12.1 4.1 2.3 2 1 0 2 2 2 0 CagA exotoxin WD40_alt PF14077.6 KFM79526.1 - 0.38 10.6 0.1 0.38 10.6 0.1 4.0 5 1 1 6 6 5 0 Alternative WD40 repeat motif Fez1 PF06818.15 KFM79526.1 - 0.59 10.6 67.8 0.49 10.8 19.2 4.2 1 1 2 3 3 3 0 Fez1 DUF1664 PF07889.12 KFM79526.1 - 0.64 10.1 41.4 0.069 13.2 2.9 4.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF3095 PF11294.8 KFM79526.1 - 0.65 9.0 9.0 0.47 9.5 7.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3095) DUF641 PF04859.12 KFM79526.1 - 0.82 10.0 56.8 0.39 11.0 7.5 5.4 2 1 3 5 5 5 0 Plant protein of unknown function (DUF641) HOOK PF05622.12 KFM79526.1 - 1.1 7.3 71.2 0.13 10.4 27.8 3.0 1 1 2 3 3 3 0 HOOK protein FPP PF05911.11 KFM79526.1 - 1.2 7.2 73.2 0.39 8.9 33.3 2.7 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil CSN5_C PF18323.1 KFM79526.1 - 1.6 9.7 25.7 1.4e+02 3.4 10.7 4.1 2 2 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Prefoldin PF02996.17 KFM79526.1 - 5.2 7.0 58.7 0.31 11.0 1.9 7.0 6 1 1 7 7 7 0 Prefoldin subunit Fib_alpha PF08702.10 KFM79526.1 - 5.3 7.2 53.8 13 5.9 7.6 4.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Vac_Fusion PF02346.16 KFM79526.1 - 8.7 6.1 16.5 4.2 7.1 0.6 5.3 4 1 0 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 ERM PF00769.19 KFM79526.1 - 9.1 6.0 74.8 0.67 9.7 26.0 3.3 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Piwi PF02171.17 KFM79527.1 - 4.1e-98 328.3 0.0 6.8e-98 327.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KFM79527.1 - 2e-20 73.0 1.3 3.8e-20 72.1 1.3 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KFM79527.1 - 2.5e-19 68.7 0.0 5.2e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KFM79527.1 - 4.8e-18 66.1 0.0 1.5e-17 64.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoMid PF16487.5 KFM79527.1 - 2.3e-16 59.8 0.0 5.9e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 KFM79527.1 - 2e-10 40.8 0.0 2.2e-08 34.3 0.0 3.0 2 0 0 2 2 2 1 Argonaute linker 2 domain RT_RNaseH PF17917.1 KFM79528.1 - 0.0005 20.3 0.0 0.00064 20.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glyco_hydro_31 PF01055.26 KFM79530.1 - 4.1e-64 217.4 0.4 5.2e-64 217.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 KFM79530.1 - 8.9e-06 25.9 0.1 3.2e-05 24.1 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) eIF3_subunit PF08597.10 KFM79531.1 - 0.14 12.0 0.6 7.1 6.5 0.3 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Ribosomal_S14 PF00253.21 KFM79532.1 - 5.8e-14 51.6 3.1 6.6e-14 51.4 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-dskA_traR PF01258.17 KFM79532.1 - 0.024 14.6 1.4 0.77 9.8 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-H2C2_2 PF13465.6 KFM79533.1 - 8.5e-118 380.1 139.8 3.3e-09 36.7 2.9 19.1 19 0 0 19 19 19 19 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79533.1 - 8.9e-75 243.2 160.7 3.7e-06 27.1 0.9 18.1 18 0 0 18 18 18 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79533.1 - 1.1e-52 172.1 146.1 0.00054 20.6 0.6 17.5 18 0 0 18 18 17 16 C2H2-type zinc finger zf-met PF12874.7 KFM79533.1 - 9.1e-43 143.5 143.4 0.00029 21.1 0.7 17.7 18 0 0 18 18 18 14 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM79533.1 - 9.9e-26 89.5 99.7 0.024 14.9 0.1 17.4 17 0 0 17 17 17 11 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM79533.1 - 8.5e-21 73.7 58.2 0.076 13.1 0.0 15.8 7 3 10 17 17 16 6 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 KFM79533.1 - 1.7e-16 59.7 105.9 0.0086 16.1 1.3 16.8 17 0 0 17 17 17 10 C2H2-type zinc finger BolA PF01722.18 KFM79533.1 - 1.1e-11 44.9 32.5 0.67 10.3 0.4 11.5 2 2 9 11 11 11 5 BolA-like protein zf-C2HC_2 PF13913.6 KFM79533.1 - 8e-11 41.6 71.3 0.79 9.7 0.1 15.3 15 0 0 15 15 14 5 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFM79533.1 - 2.2e-10 40.1 120.5 0.02 14.6 0.5 17.7 17 1 0 17 17 17 10 C2H2-type zinc-finger domain zf-DBF PF07535.12 KFM79533.1 - 3.5e-06 27.0 77.2 4.7 7.4 0.2 16.5 17 0 0 17 17 17 1 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM79533.1 - 0.00028 21.0 81.9 0.11 12.7 6.4 7.9 1 1 8 9 9 9 6 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_11 PF16622.5 KFM79533.1 - 0.0013 18.5 116.2 0.015 15.0 1.2 16.6 17 0 0 17 17 17 7 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFM79533.1 - 0.0032 17.3 87.7 1.9 8.4 0.3 16.6 7 5 10 17 17 17 2 C2H2 type zinc-finger (1 copy) Root_cap PF06830.11 KFM79533.1 - 0.0069 16.5 0.1 33 4.7 0.0 5.3 4 1 2 6 6 6 0 Root cap C1_1 PF00130.22 KFM79533.1 - 0.02 14.8 101.3 1.3 8.9 8.2 13.1 3 2 9 13 13 13 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IGPD PF00475.18 KFM79533.1 - 0.025 14.9 19.1 6 7.2 0.2 7.0 3 2 3 7 7 7 0 Imidazoleglycerol-phosphate dehydratase Ala_racemase_C PF00842.21 KFM79533.1 - 0.11 12.3 1.1 7.7 6.4 0.1 2.4 1 1 1 2 2 2 0 Alanine racemase, C-terminal domain Zf_RING PF16744.5 KFM79533.1 - 0.14 12.3 89.2 5 7.3 0.1 16.4 1 1 14 15 15 15 0 KIAA1045 RING finger M-factor PF03855.13 KFM79533.1 - 0.25 11.5 1.9 32 4.8 0.0 4.5 4 0 0 4 4 4 0 M-factor Glyco_hydro_20 PF00728.22 KFM79533.1 - 0.54 9.6 5.2 1.2 8.5 0.1 3.1 1 1 2 4 4 4 0 Glycosyl hydrolase family 20, catalytic domain zinc_ribbon_15 PF17032.5 KFM79533.1 - 0.75 10.6 76.7 3.7 8.4 2.5 9.2 2 1 5 9 9 9 0 zinc-ribbon family GAGA PF09237.11 KFM79533.1 - 0.82 9.5 0.0 0.82 9.5 0.0 11.6 3 2 11 15 15 15 0 GAGA factor Mga PF05043.13 KFM79533.1 - 0.95 10.1 6.0 37 5.0 0.1 5.3 4 2 2 7 7 7 0 Mga helix-turn-helix domain DUF2256 PF10013.9 KFM79533.1 - 2.3 8.4 75.5 23 5.2 0.2 16.4 17 0 0 17 17 17 0 Uncharacterized protein conserved in bacteria (DUF2256) Baculo_IE-1 PF05290.11 KFM79533.1 - 5.4 7.0 65.4 7.4 6.5 1.4 10.7 1 1 9 10 10 10 0 Baculovirus immediate-early protein (IE-0) zf-MYST PF17772.1 KFM79533.1 - 5.7 6.6 93.0 0.21 11.2 0.3 15.0 7 4 10 17 17 17 0 MYST family zinc finger domain MFS_1 PF07690.16 KFM79535.1 - 2.2e-06 26.9 0.5 2.3e-06 26.8 0.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1206 PF06724.11 KFM79535.1 - 0.02 15.0 0.1 0.02 14.9 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) MFS_1 PF07690.16 KFM79536.1 - 5.6e-08 32.1 13.2 6.8e-08 31.8 13.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFM79536.1 - 0.00023 20.6 0.9 0.00028 20.3 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Osw5 PF17062.5 KFM79536.1 - 3.3 7.9 11.6 0.53 10.4 5.5 2.6 2 1 1 3 3 3 0 Outer spore wall 5 Chitin_bind_4 PF00379.23 KFM79537.1 - 3.1e-10 40.4 1.6 4.1e-10 40.0 1.6 1.1 1 0 0 1 1 1 1 Insect cuticle protein Inhibitor_I68 PF10468.9 KFM79539.1 - 4.2e-05 23.9 12.3 5.9e-05 23.4 12.3 1.2 1 0 0 1 1 1 1 Carboxypeptidase inhibitor I68 DUF4730 PF15873.5 KFM79540.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4730) HpaB PF03241.13 KFM79541.1 - 0.045 12.8 0.0 0.046 12.8 0.0 1.0 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Isochorismatase PF00857.20 KFM79542.1 - 4.1e-31 108.5 0.1 1.1e-30 107.1 0.1 1.6 1 1 0 1 1 1 1 Isochorismatase family EF-hand_5 PF13202.6 KFM79542.1 - 3.4e-06 26.3 0.2 9.9e-06 24.8 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KFM79542.1 - 6.4e-05 22.7 0.7 0.00018 21.3 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM79542.1 - 0.00016 21.0 0.4 0.00043 19.6 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFM79542.1 - 0.021 14.8 0.1 0.021 14.8 0.1 2.2 3 0 0 3 3 3 0 EF-hand domain DUF3105 PF11303.8 KFM79542.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) MFS_1 PF07690.16 KFM79543.1 - 2.9e-28 98.8 9.0 2.2e-18 66.3 1.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM79543.1 - 1e-25 90.6 20.3 2.4e-23 82.8 20.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KFM79543.1 - 0.0041 15.7 3.5 0.0041 15.7 3.5 3.5 3 1 1 4 4 4 2 MFS/sugar transport protein zf-RNPHF PF08080.12 KFM79543.1 - 1.7 8.6 3.9 30 4.7 0.2 3.4 4 0 0 4 4 4 0 RNPHF zinc finger Sugar_tr PF00083.24 KFM79544.1 - 3.7e-32 111.8 11.1 6.4e-32 111.0 11.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM79544.1 - 1.6e-28 99.7 26.1 1.7e-24 86.4 14.5 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KFM79544.1 - 3.2e-06 25.9 13.0 0.00039 19.0 6.0 2.6 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) OTU PF02338.19 KFM79547.1 - 1.1e-16 61.4 0.9 2.9e-16 60.1 0.9 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFM79547.1 - 0.002 17.6 6.3 0.086 12.3 3.2 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain LepB_GAP_N PF18172.1 KFM79547.1 - 0.073 13.0 0.2 0.2 11.5 0.2 1.7 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain Ion_trans PF00520.31 KFM79548.1 - 0.019 14.2 0.7 0.026 13.7 0.7 1.2 1 0 0 1 1 1 0 Ion transport protein MT-A70 PF05063.14 KFM79549.1 - 1.3e-61 207.4 0.6 3.5e-61 206.1 0.0 2.0 2 0 0 2 2 2 1 MT-A70 Neuromodulin_N PF10580.9 KFM79549.1 - 0.12 12.2 0.5 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 Gap junction protein N-terminal region Rsm22 PF09243.10 KFM79549.1 - 0.2 10.9 0.9 0.39 9.9 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 zf-C3HC4_3 PF13920.6 KFM79551.1 - 7.3e-13 48.2 12.7 7.3e-13 48.2 12.7 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 KFM79551.1 - 6.1e-05 22.8 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-RanBP PF00641.18 KFM79551.1 - 0.004 16.4 4.6 0.004 16.4 4.6 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-RING_2 PF13639.6 KFM79551.1 - 0.017 15.5 11.5 0.017 15.5 11.5 2.8 2 0 0 2 2 2 0 Ring finger domain DUF35_N PF12172.8 KFM79551.1 - 4.2 7.3 9.2 0.23 11.4 0.9 2.8 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-RanBP PF00641.18 KFM79552.1 - 2.5e-14 52.3 20.1 1.7e-07 30.4 5.5 2.1 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zinc-ribbon_6 PF10005.9 KFM79552.1 - 0.039 14.6 5.0 3.4 8.4 1.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF2039 PF10217.9 KFM79552.1 - 0.049 14.0 6.4 0.085 13.2 1.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DZR PF12773.7 KFM79552.1 - 0.13 12.4 11.1 1.2 9.2 11.3 2.1 1 1 1 2 2 2 0 Double zinc ribbon DUF1258 PF06869.12 KFM79552.1 - 0.51 9.8 7.7 3.6 7.0 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) DUF35_N PF12172.8 KFM79552.1 - 0.79 9.7 8.5 4.7 7.2 0.7 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF1660 PF07874.11 KFM79552.1 - 3.6 8.2 6.9 7 7.2 0.7 2.3 1 1 1 2 2 2 0 Prophage protein (DUF1660) zf-C2HE PF16278.5 KFM79552.1 - 6.1 7.4 7.4 7.6 7.1 1.4 2.7 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 KFM79552.1 - 7.3 6.7 10.7 1.9e+02 2.1 10.6 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 KFM79552.1 - 9 6.0 8.1 13 5.5 0.2 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger HalOD2 PF18547.1 KFM79552.1 - 9.2 6.3 15.0 3.9 7.4 8.8 3.0 1 1 1 2 2 2 0 Halobacterial output domain 2 RecR PF02132.15 KFM79552.1 - 9.8 5.8 12.3 0.42 10.2 1.0 3.0 2 1 0 2 2 2 0 RecR protein zf-CCHC_2 PF13696.6 KFM79552.1 - 9.8 6.1 8.7 24 4.9 0.3 3.1 3 0 0 3 3 3 0 Zinc knuckle CshA_NR2 PF18651.1 KFM79553.1 - 0.028 13.6 0.5 0.05 12.8 0.5 1.3 1 0 0 1 1 1 0 Surface adhesin CshA non-repetitive domain 2 MBD PF01429.19 KFM79554.1 - 1.9e-09 37.1 0.0 5.6e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Methyl-CpG binding domain F-box PF00646.33 KFM79554.1 - 0.0003 20.6 0.6 0.0011 18.8 0.6 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFM79554.1 - 0.00046 20.0 0.6 0.00095 19.0 0.6 1.5 1 0 0 1 1 1 1 F-box-like PHD PF00628.29 KFM79554.1 - 0.34 10.8 7.7 1.6 8.7 7.7 2.2 1 0 0 1 1 1 0 PHD-finger LRR_9 PF14580.6 KFM79555.1 - 0.0016 18.0 0.1 0.011 15.3 0.0 2.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 KFM79555.1 - 0.0092 16.4 3.2 3.5 8.2 0.0 5.1 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) SRP14 PF02290.15 KFM79556.1 - 1.4e-26 92.7 0.0 1.7e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF5009 PF16401.5 KFM79557.1 - 6.8e-06 25.8 1.2 6.8e-06 25.8 1.2 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF5009) DUF2721 PF11026.8 KFM79557.1 - 1 9.2 6.8 0.34 10.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Hira PF07569.11 KFM79558.1 - 4.3e-06 26.6 0.0 5.9e-05 22.9 0.0 2.8 2 0 0 2 2 2 1 TUP1-like enhancer of split Coatomer_WDAD PF04053.14 KFM79558.1 - 6.3e-06 25.5 19.6 0.0012 17.9 3.6 4.6 3 3 2 6 6 6 3 Coatomer WD associated region TPR_2 PF07719.17 KFM79558.1 - 2.6e-05 24.0 37.6 0.2 11.8 0.0 11.3 12 1 1 13 13 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM79558.1 - 0.00017 21.3 21.0 18 5.6 0.1 10.2 9 2 1 10 10 9 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFM79558.1 - 0.00075 18.9 0.8 1.7 8.2 0.1 3.6 3 0 0 3 3 3 2 SHNi-TPR Mt_ATP_synt PF15704.5 KFM79558.1 - 0.036 14.0 6.5 1.4 8.8 0.0 3.0 2 1 0 2 2 2 0 Mitochondrial ATP synthase subunit DUF2524 PF10732.9 KFM79558.1 - 0.04 14.2 0.4 0.04 14.2 0.4 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF2524) TPR_14 PF13428.6 KFM79558.1 - 0.052 14.4 12.1 20 6.3 0.0 7.9 7 1 2 9 9 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM79558.1 - 0.057 13.7 26.8 0.073 13.4 0.6 8.0 7 1 1 8 8 8 0 Tetratricopeptide repeat Clathrin PF00637.20 KFM79558.1 - 0.087 12.7 33.7 1.1 9.2 3.4 8.3 3 2 4 8 8 8 0 Region in Clathrin and VPS TPR_1 PF00515.28 KFM79558.1 - 0.4 10.6 35.7 1.4 8.8 0.1 10.2 10 1 1 11 11 11 0 Tetratricopeptide repeat Tfb2_C PF18307.1 KFM79558.1 - 0.46 11.0 4.3 1e+02 3.4 0.0 5.2 5 0 0 5 5 4 0 Transcription factor Tfb2 (p52) C-terminal domain PPR PF01535.20 KFM79558.1 - 0.77 10.2 10.4 58 4.3 0.2 7.0 6 0 0 6 6 6 0 PPR repeat PPR_2 PF13041.6 KFM79558.1 - 2.2 8.6 4.4 15 5.8 0.0 4.5 5 0 0 5 5 5 0 PPR repeat family TPR_8 PF13181.6 KFM79558.1 - 2.2 8.7 21.1 20 5.7 0.2 8.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFM79558.1 - 3 7.9 11.2 23 5.1 0.5 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KFM79558.1 - 5 7.3 23.7 2.7 8.1 2.3 6.5 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain DUF349 PF03993.12 KFM79558.1 - 8.2 6.8 8.4 0.64 10.4 0.5 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) LRR_8 PF13855.6 KFM79559.1 - 7.7e-25 86.4 14.6 6.2e-15 54.7 4.3 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 KFM79559.1 - 7.1e-09 35.7 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM79559.1 - 1.2e-06 28.8 12.8 5.8e-05 23.4 1.9 3.6 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM79559.1 - 0.0006 20.0 6.6 1 10.1 0.0 4.6 4 1 0 4 4 4 2 Leucine Rich Repeat Pr_beta_C PF12465.8 KFM79560.1 - 0.17 11.3 1.1 0.31 10.5 1.1 1.3 1 0 0 1 1 1 0 Proteasome beta subunits C terminal Calcipressin PF04847.12 KFM79561.1 - 1.2e-38 132.8 0.4 1.2e-38 132.8 0.4 1.7 2 1 0 2 2 2 1 Calcipressin RRM_1 PF00076.22 KFM79561.1 - 0.0043 16.8 0.3 0.0071 16.2 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HC5HC2H PF13771.6 KFM79562.1 - 4.7e-16 58.8 4.8 4.7e-16 58.8 4.8 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFM79562.1 - 1.9e-06 28.0 6.7 1.9e-06 28.0 6.7 2.7 1 1 2 3 3 3 1 PHD-zinc-finger like domain zf-C4_ClpX PF06689.13 KFM79562.1 - 2.1 8.3 20.0 0.42 10.5 3.5 3.5 3 0 0 3 3 3 0 ClpX C4-type zinc finger Prim_Zn_Ribbon PF08273.12 KFM79563.1 - 0.0054 17.0 1.3 0.015 15.6 1.3 1.7 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase PHD_2 PF13831.6 KFM79563.1 - 0.081 12.5 5.1 0.13 11.9 3.2 2.3 2 0 0 2 2 2 0 PHD-finger Sulfatase PF00884.23 KFM79564.1 - 1.2e-68 231.8 0.1 1.5e-68 231.5 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFM79564.1 - 1.1e-06 28.4 0.1 1.7e-05 24.6 0.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 KFM79564.1 - 0.00027 20.8 0.0 0.00052 19.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 KFM79564.1 - 0.00037 20.7 0.1 0.052 13.8 0.1 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KFM79564.1 - 0.00051 20.8 0.0 0.001 19.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase FH2 PF02181.23 KFM79565.1 - 1.5e-113 379.8 13.7 1.9e-113 379.4 13.7 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain TMF_TATA_bd PF12325.8 KFM79565.1 - 0.0023 18.1 0.2 0.0023 18.1 0.2 2.8 3 2 0 3 3 2 1 TATA element modulatory factor 1 TATA binding DUF1043 PF06295.12 KFM79565.1 - 0.027 14.4 4.3 0.73 9.8 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) ACP_PD PF04336.12 KFM79565.1 - 0.059 13.8 0.9 0.18 12.3 0.2 2.2 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase Tox-REase-5 PF15648.6 KFM79565.1 - 0.074 13.6 0.9 0.7 10.4 0.3 2.6 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 LXG PF04740.12 KFM79565.1 - 0.3 10.8 11.1 1.2 8.8 1.8 3.1 2 2 1 3 3 3 0 LXG domain of WXG superfamily TMPIT PF07851.13 KFM79565.1 - 0.39 9.9 4.1 0.27 10.4 1.9 1.7 1 1 0 1 1 1 0 TMPIT-like protein KxDL PF10241.9 KFM79565.1 - 0.42 10.9 4.2 4.2 7.7 1.7 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein Tup_N PF08581.10 KFM79565.1 - 0.7 10.2 10.9 0.065 13.5 1.4 3.3 2 1 1 3 3 3 0 Tup N-terminal FlaC_arch PF05377.11 KFM79565.1 - 1.8 9.0 7.9 15 6.1 0.3 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 KFM79565.1 - 3.4 7.5 12.9 4.1 7.2 3.1 3.9 3 2 0 3 3 3 0 Phage minor structural protein GP20 ORC5_C PF14630.6 KFM79565.1 - 3.9 6.9 7.4 12 5.3 7.3 1.9 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus KH_1 PF00013.29 KFM79567.1 - 6.2e-40 134.9 12.4 2.7e-15 55.9 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFM79567.1 - 8.8e-12 44.7 7.8 4.9e-06 26.3 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFM79567.1 - 0.00015 21.5 6.4 0.063 13.2 0.1 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KFM79567.1 - 0.00025 21.1 8.0 0.045 13.8 0.3 3.4 3 0 0 3 3 3 2 NusA-like KH domain 7tm_1 PF00001.21 KFM79568.1 - 2.6e-08 33.5 2.4 2.8e-08 33.4 2.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EF-hand_6 PF13405.6 KFM79570.1 - 7.4e-22 75.4 2.9 1e-05 25.0 0.0 5.1 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 KFM79570.1 - 9.7e-22 77.2 5.6 2.4e-13 50.3 0.8 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM79570.1 - 5.2e-21 72.6 8.5 3.3e-06 26.2 0.0 4.9 6 0 0 6 6 6 4 EF hand EF-hand_5 PF13202.6 KFM79570.1 - 2.7e-17 61.4 3.9 0.00011 21.5 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFM79570.1 - 1.9e-13 50.0 9.6 1.9e-09 37.2 1.0 4.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KFM79570.1 - 0.0016 18.7 0.3 0.025 14.9 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain p25-alpha PF05517.12 KFM79570.1 - 0.0088 16.2 0.9 0.37 10.9 0.0 2.6 2 1 1 3 3 3 1 p25-alpha EF-hand_10 PF14788.6 KFM79570.1 - 0.017 15.0 1.1 2.6 8.0 0.1 3.0 2 1 1 3 3 3 0 EF hand EF-hand_14 PF17959.1 KFM79570.1 - 0.027 14.8 0.3 0.24 11.8 0.2 2.4 2 1 0 2 2 2 0 EF-hand domain DUF1456 PF07308.13 KFM79570.1 - 0.047 14.0 0.2 10 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Caleosin PF05042.13 KFM79570.1 - 0.059 13.3 0.5 7.1 6.5 0.0 2.7 1 1 2 3 3 3 0 Caleosin related protein TRAPP PF04051.16 KFM79571.1 - 3.8e-37 127.2 0.1 4.7e-37 126.9 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Proteasome PF00227.26 KFM79572.1 - 1.8e-61 206.9 0.2 2.5e-61 206.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM79572.1 - 3.1e-14 52.3 0.1 6.7e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature YabP PF07873.11 KFM79572.1 - 0.079 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 YabP family zf-C3HC4_3 PF13920.6 KFM79573.1 - 1.6e-11 43.8 5.8 2.6e-11 43.2 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM79573.1 - 7.6e-11 42.2 10.0 1.2e-10 41.5 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM79573.1 - 4.4e-10 39.2 10.1 7.7e-10 38.4 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM79573.1 - 1.3e-09 37.9 4.0 1.3e-09 37.9 4.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM79573.1 - 5.2e-09 35.8 9.7 8.6e-09 35.1 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM79573.1 - 1.9e-08 34.1 6.2 3.4e-08 33.3 6.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM79573.1 - 2.2e-07 30.6 8.0 1.2e-06 28.2 8.5 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFM79573.1 - 1.2e-06 28.7 5.8 2.5e-06 27.6 5.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFM79573.1 - 1.6e-05 25.0 7.6 4e-05 23.7 7.8 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFM79573.1 - 0.0017 18.4 1.7 0.0041 17.1 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KFM79573.1 - 0.0055 16.6 2.7 0.012 15.5 2.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein YwiC PF14256.6 KFM79573.1 - 0.1 12.9 4.1 0.1 12.9 2.5 1.9 2 0 0 2 2 1 0 YwiC-like protein Zn_ribbon_17 PF17120.5 KFM79573.1 - 0.15 11.7 4.7 0.33 10.6 4.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KFM79573.1 - 0.15 11.9 4.1 0.3 10.9 4.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.12 KFM79573.1 - 0.16 12.0 6.8 0.27 11.2 6.8 1.4 1 0 0 1 1 1 0 zinc-ribbons TerY_C PF15616.6 KFM79573.1 - 0.21 11.7 1.6 0.4 10.8 1.6 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.6 KFM79573.1 - 0.25 11.2 9.0 6.4 6.6 5.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain GAGA PF09237.11 KFM79573.1 - 0.37 10.6 3.6 8.1 6.3 0.2 3.2 3 0 0 3 3 3 0 GAGA factor Phospholamban PF04272.14 KFM79573.1 - 1 8.9 5.9 0.54 9.8 0.1 2.5 2 0 0 2 2 2 0 Phospholamban zf-P11 PF03854.14 KFM79573.1 - 1.3 8.8 8.0 6.5 6.5 6.8 2.6 2 1 1 3 3 3 0 P-11 zinc finger DZR PF12773.7 KFM79573.1 - 1.8 8.7 6.3 4.5 7.4 6.3 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_5 PF17121.5 KFM79573.1 - 6.1 6.8 9.4 39 4.2 9.4 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 KFM79573.1 - 6.2 6.5 10.4 15 5.3 0.4 2.4 2 0 0 2 2 2 0 RecR protein GMP_synt_C PF00958.22 KFM79574.1 - 7.5e-19 67.6 0.0 2.3e-10 40.4 0.0 2.8 2 1 0 2 2 2 2 GMP synthase C terminal domain GATase PF00117.28 KFM79574.1 - 7e-18 65.1 0.1 1.4e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KFM79574.1 - 1.7e-09 37.1 0.2 2.7e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KFM79574.1 - 2.9e-06 27.2 0.1 5.1e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KFM79574.1 - 2.4e-05 24.0 0.0 0.00017 21.2 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KFM79574.1 - 0.00016 20.6 0.0 0.00062 18.7 0.0 2.0 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.20 KFM79574.1 - 0.0025 17.6 0.2 0.0089 15.8 0.1 2.0 2 0 0 2 2 2 1 PP-loop family ThiI PF02568.14 KFM79574.1 - 0.0091 15.6 0.1 0.023 14.3 0.1 1.7 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 KFM79574.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Arginosuc_synth PF00764.19 KFM79574.1 - 0.029 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 KFM79574.1 - 0.043 13.8 0.3 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family ICAT PF06384.11 KFM79575.1 - 5.6e-25 87.4 0.3 1.9e-24 85.7 0.1 1.9 2 0 0 2 2 2 1 Beta-catenin-interacting protein ICAT CAMP_factor PF07373.11 KFM79575.1 - 0.0016 18.1 0.7 0.0016 18.1 0.7 1.6 1 1 1 2 2 2 1 CAMP factor (Cfa) TMCO5 PF14992.6 KFM79575.1 - 0.053 13.1 6.8 0.072 12.7 6.8 1.2 1 0 0 1 1 1 0 TMCO5 family DMAP_binding PF06464.11 KFM79575.1 - 0.065 14.0 0.2 0.065 14.0 0.2 2.0 2 0 0 2 2 2 0 DMAP1-binding Domain Replic_Relax PF13814.6 KFM79575.1 - 0.091 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Replication-relaxation DUF3313 PF11769.8 KFM79575.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) FtsK_alpha PF17854.1 KFM79575.1 - 0.3 11.3 1.5 18 5.5 0.4 2.4 1 1 1 2 2 2 0 FtsK alpha domain FUSC PF04632.12 KFM79575.1 - 0.31 9.5 1.3 0.35 9.4 1.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Swi5 PF07061.11 KFM79575.1 - 0.39 10.8 6.4 0.22 11.6 2.3 2.2 2 0 0 2 2 2 0 Swi5 Wbp11 PF09429.10 KFM79575.1 - 1.4 9.4 9.8 0.92 9.9 0.6 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 GvpG PF05120.12 KFM79575.1 - 2.7 8.1 10.7 0.51 10.4 0.8 2.5 2 0 0 2 2 2 0 Gas vesicle protein G Caps_synth_GfcC PF06251.11 KFM79575.1 - 3.6 7.2 6.5 3 7.4 1.1 2.1 1 1 1 2 2 2 0 Capsule biosynthesis GfcC Vir_act_alpha_C PF10400.9 KFM79575.1 - 4 8.2 6.5 4.6 8.0 0.4 2.5 2 1 0 2 2 2 0 Virulence activator alpha C-term Synaptobrevin PF00957.21 KFM79576.1 - 2.2e-29 101.1 1.8 2.3e-29 101.0 1.8 1.0 1 0 0 1 1 1 1 Synaptobrevin Virul_fac_BrkB PF03631.15 KFM79576.1 - 0.013 15.1 0.1 0.015 15.0 0.1 1.0 1 0 0 1 1 1 0 Virulence factor BrkB Shisa PF13908.6 KFM79576.1 - 0.032 14.5 0.1 0.032 14.5 0.1 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Seryl_tRNA_N PF02403.22 KFM79576.1 - 0.089 13.0 0.5 0.1 12.9 0.5 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2207 PF09972.9 KFM79576.1 - 0.11 11.3 0.1 0.11 11.2 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Use1 PF09753.9 KFM79576.1 - 0.11 12.2 0.4 0.14 11.8 0.4 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 XhlA PF10779.9 KFM79576.1 - 0.39 11.0 0.2 0.39 11.0 0.2 2.1 2 0 0 2 2 2 0 Haemolysin XhlA ASFV_J13L PF05568.11 KFM79576.1 - 0.73 9.6 2.4 0.99 9.1 2.4 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Insulin_TMD PF17870.1 KFM79576.1 - 1.1 9.4 7.8 1.5 9.0 7.8 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ig_3 PF13927.6 KFM79578.1 - 8.1e-18 64.8 0.0 5.9e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM79578.1 - 6.9e-17 61.3 0.0 4.5e-07 29.8 0.1 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFM79578.1 - 8.6e-15 54.8 0.0 2.2e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM79578.1 - 2.3e-14 53.2 0.0 5.1e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM79578.1 - 7.7e-12 45.2 0.1 2.1e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM79578.1 - 0.0026 17.9 0.4 0.74 10.0 0.1 3.3 2 2 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 KFM79578.1 - 0.01 16.2 0.0 0.16 12.4 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFM79578.1 - 0.036 14.1 0.0 1.7 8.7 0.1 2.7 2 1 0 2 2 2 0 C17orf99 Ig domain Ig_4 PF16680.5 KFM79578.1 - 0.067 13.5 0.0 8.2 6.8 0.0 2.7 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 KFM79578.1 - 0.082 13.1 0.0 5.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C2-set domain LRR_8 PF13855.6 KFM79579.1 - 1.6e-10 40.5 2.1 1.6e-10 40.5 2.1 1.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KFM79579.1 - 4.4e-07 30.1 14.1 1.3e-05 25.5 4.9 2.6 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM79579.1 - 6.6e-05 22.9 5.4 4.1 8.3 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 KFM79579.1 - 0.0031 17.4 9.1 1.1 9.5 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeat Sec23_helical PF04815.15 KFM79579.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 helical domain LRR_9 PF14580.6 KFM79579.1 - 0.057 12.9 0.2 0.061 12.8 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeat DUF2452 PF10504.9 KFM79579.1 - 0.061 12.8 0.5 0.099 12.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2452) I-set PF07679.16 KFM79580.1 - 1.5e-10 40.9 0.0 1.8e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM79580.1 - 1.8e-09 38.1 0.0 2.1e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM79580.1 - 3.6e-06 27.2 0.0 5.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM79580.1 - 1.9e-05 24.8 0.0 3.6e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFM79580.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain DUF4690 PF15756.5 KFM79582.1 - 0.00035 21.1 0.4 0.0013 19.3 0.2 1.9 1 1 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 KFM79582.1 - 0.0034 17.5 0.1 0.0055 16.8 0.1 1.3 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.6 KFM79582.1 - 0.019 13.8 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Amnionless EGF_2 PF07974.13 KFM79584.1 - 0.0064 16.8 8.5 0.011 16.1 8.5 1.3 1 0 0 1 1 1 1 EGF-like domain DUF2325 PF10087.9 KFM79584.1 - 0.057 13.5 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Y_Y_Y PF07495.13 KFM79585.1 - 1.3e-06 28.2 0.8 0.13 12.2 0.0 3.6 3 0 0 3 3 3 2 Y_Y_Y domain DUF5013 PF16405.5 KFM79585.1 - 0.00018 21.8 3.1 4.2 7.6 0.2 3.4 1 1 1 3 3 3 3 Domain of unknown function (DUF5013) PKD PF00801.20 KFM79585.1 - 0.00025 20.8 0.4 0.17 11.8 0.1 3.6 3 0 0 3 3 3 1 PKD domain Cupredoxin_1 PF13473.6 KFM79585.1 - 0.00043 20.3 0.7 1.2 9.3 0.0 3.6 1 1 2 3 3 3 2 Cupredoxin-like domain He_PIG PF05345.12 KFM79585.1 - 0.0043 17.2 0.5 10 6.4 0.0 3.6 3 0 0 3 3 3 1 Putative Ig domain DUF4625 PF15418.6 KFM79585.1 - 0.0061 16.8 0.0 7.9 6.7 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4625) PKD_2 PF16407.5 KFM79585.1 - 0.01 16.0 3.5 7.8 6.7 0.0 3.3 1 1 1 3 3 3 0 PKD-like family BPA_C PF18040.1 KFM79585.1 - 0.016 15.1 1.1 0.16 11.9 0.0 2.7 3 0 0 3 3 3 0 beta porphyranase A C-terminal EB PF01683.18 KFM79585.1 - 0.62 10.4 4.6 1.1 9.7 4.6 1.3 1 0 0 1 1 1 0 EB module MANEC PF07502.14 KFM79586.1 - 0.00014 22.0 0.3 0.00018 21.7 0.3 1.2 1 0 0 1 1 1 1 MANEC domain PAN_3 PF08277.12 KFM79586.1 - 0.0085 15.9 0.6 0.011 15.5 0.6 1.2 1 0 0 1 1 1 1 PAN-like domain PDEase_I PF00233.19 KFM79587.1 - 1.8e-11 44.2 0.2 1.9e-11 44.1 0.2 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF4521 PF15021.6 KFM79587.1 - 0.072 13.0 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) GAF PF01590.26 KFM79589.1 - 5.1e-12 46.6 0.0 1.7e-07 32.0 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFM79589.1 - 9.8e-06 25.9 0.0 0.021 15.1 0.0 2.1 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFM79589.1 - 3.1e-05 24.3 0.1 0.0002 21.7 0.0 2.3 2 1 2 4 4 4 1 GAF domain SPG48 PF14764.6 KFM79589.1 - 0.036 14.6 0.3 0.061 13.8 0.3 1.4 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking MFS_1 PF07690.16 KFM79590.1 - 9.6e-17 60.9 19.6 9.6e-17 60.9 19.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KFM79591.1 - 8e-08 32.0 0.1 1.1e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM79591.1 - 0.00025 20.4 0.1 0.00037 19.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 KFM79591.1 - 0.063 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.25 KFM79592.1 - 1.3e-10 41.1 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain TLD PF07534.16 KFM79594.1 - 8.5e-34 116.7 0.1 1e-33 116.5 0.1 1.1 1 0 0 1 1 1 1 TLD LysM PF01476.20 KFM79595.1 - 9.3e-10 38.4 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain Glutaredoxin PF00462.24 KFM79596.1 - 1.3e-21 76.5 0.0 2.3e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin 6PF2K PF01591.18 KFM79596.1 - 0.09 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase p31comet PF06581.12 KFM79597.1 - 4.1e-18 65.5 0.4 3.5e-08 32.9 0.0 2.1 1 1 1 2 2 2 2 Mad1 and Cdc20-bound-Mad2 binding CD45 PF12567.8 KFM79597.1 - 0.033 14.1 1.7 6.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Leukocyte receptor CD45 Ribosomal_L30_N PF08079.12 KFM79598.1 - 1.1e-28 99.2 15.5 1.9e-28 98.5 14.5 1.8 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KFM79598.1 - 3.8e-19 68.3 1.6 3.8e-19 68.3 1.6 2.6 3 1 1 4 4 4 1 Ribosomal protein L30p/L7e Mak10 PF04112.13 KFM79599.1 - 6.8e-28 97.3 0.3 8e-23 80.8 0.1 3.3 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase RYDR_ITPR PF01365.21 KFM79599.1 - 0.02 14.3 0.3 0.38 10.1 0.0 2.5 2 0 0 2 2 2 0 RIH domain MSA-2c PF12238.8 KFM79599.1 - 0.27 11.2 2.4 23 4.9 0.1 3.3 4 0 0 4 4 4 0 Merozoite surface antigen 2c Plasmid_RAQPRD PF09686.10 KFM79599.1 - 0.37 11.1 1.9 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF2508 PF10704.9 KFM79599.1 - 0.4 10.9 4.5 2.1 8.6 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) TIP120 PF08623.10 KFM79600.1 - 5.5e-67 224.7 6.4 3.7e-64 215.5 0.6 5.6 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KFM79600.1 - 1.7e-18 66.8 9.6 0.0017 18.7 0.0 8.9 7 2 2 9 9 9 5 HEAT repeats HEAT PF02985.22 KFM79600.1 - 1.2e-14 53.1 16.3 0.14 12.5 0.0 12.8 13 0 0 13 13 13 2 HEAT repeat HEAT_EZ PF13513.6 KFM79600.1 - 4.3e-09 36.7 14.2 2.7 8.6 0.0 10.9 11 2 2 13 13 12 2 HEAT-like repeat Cnd1 PF12717.7 KFM79600.1 - 5.4e-09 36.3 20.7 0.0014 18.7 1.8 7.4 4 2 4 8 8 8 3 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KFM79600.1 - 3.4e-08 33.3 9.4 0.03 14.2 0.1 8.0 7 3 1 8 8 8 2 UME (NUC010) domain CLASP_N PF12348.8 KFM79600.1 - 6.4e-07 29.2 8.9 0.091 12.3 0.0 6.3 5 2 1 6 6 6 2 CLASP N terminal MMS19_C PF12460.8 KFM79600.1 - 1.4e-05 24.4 25.8 0.00093 18.4 1.7 6.6 5 2 0 6 6 6 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KFM79600.1 - 0.00017 21.5 0.1 0.00017 21.5 0.1 6.4 7 2 1 8 8 8 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KFM79600.1 - 0.0002 21.9 10.2 0.62 10.7 0.0 7.6 7 2 2 9 9 9 1 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 KFM79600.1 - 0.0016 18.7 3.9 3.2 8.1 0.0 5.2 3 2 1 5 5 5 1 TAF6 C-terminal HEAT repeat domain VHS PF00790.19 KFM79600.1 - 0.012 15.5 6.2 0.61 9.9 0.4 4.1 3 1 0 3 3 3 0 VHS domain Arm PF00514.23 KFM79600.1 - 0.014 15.4 4.0 43 4.3 0.0 6.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat ParcG PF10274.9 KFM79600.1 - 0.055 13.6 10.8 12 6.0 0.0 6.1 4 2 2 6 6 6 0 Parkin co-regulated protein API5 PF05918.11 KFM79600.1 - 0.073 11.9 2.8 1.6 7.4 0.4 3.4 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) RTP1_C1 PF10363.9 KFM79600.1 - 0.73 10.0 12.3 3 8.0 0.2 6.3 8 1 0 8 8 8 0 Required for nuclear transport of RNA pol II C-terminus 1 BTB PF00651.31 KFM79601.1 - 4.3e-05 23.7 0.0 6.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DASH_Hsk3 PF08227.11 KFM79601.1 - 0.061 13.7 0.0 0.093 13.1 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DUF2828 PF11443.8 KFM79601.1 - 0.15 10.2 0.1 0.15 10.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ank_2 PF12796.7 KFM79602.1 - 1.9e-82 271.9 32.3 1.7e-12 47.8 4.3 12.1 2 2 10 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM79602.1 - 9.9e-74 242.8 31.0 1.9e-10 41.0 2.0 17.7 4 2 16 20 20 20 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM79602.1 - 2.8e-67 214.7 32.6 0.0002 21.5 0.0 22.2 23 1 0 23 23 23 17 Ankyrin repeat Ank_5 PF13857.6 KFM79602.1 - 2.1e-58 193.6 33.9 5.9e-09 36.0 0.2 17.9 9 5 9 19 19 19 14 Ankyrin repeats (many copies) Ank PF00023.30 KFM79602.1 - 2.3e-58 192.2 50.7 1.1e-07 31.9 0.0 21.4 22 0 0 22 22 22 16 Ankyrin repeat FYVE PF01363.21 KFM79602.1 - 5.8e-08 32.8 11.7 1.3e-07 31.7 11.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger AnkUBD PF18418.1 KFM79602.1 - 0.019 15.1 1.0 9.8 6.4 0.0 4.0 5 0 0 5 5 5 0 Ankyrin ubiquitin-binding domain I-set PF07679.16 KFM79603.1 - 1.2e-109 358.6 0.0 6.7e-27 93.4 0.1 6.3 6 0 0 6 6 6 6 Immunoglobulin I-set domain Pkinase PF00069.25 KFM79603.1 - 1.2e-69 234.6 0.1 1.7e-69 234.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 KFM79603.1 - 1.2e-64 214.9 0.0 1.7e-15 57.4 0.1 6.8 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 KFM79603.1 - 3.9e-42 142.5 0.3 2.6e-10 40.5 0.1 5.7 6 0 0 6 6 5 5 Immunoglobulin domain ig PF00047.25 KFM79603.1 - 2.2e-36 123.9 1.5 6.4e-10 39.1 0.2 6.4 7 0 0 7 7 6 4 Immunoglobulin domain Pkinase_Tyr PF07714.17 KFM79603.1 - 4.8e-32 111.3 0.0 6.9e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase V-set PF07686.17 KFM79603.1 - 2.5e-14 53.3 7.1 0.0085 16.3 0.3 8.6 6 4 0 6 6 6 3 Immunoglobulin V-set domain fn3 PF00041.21 KFM79603.1 - 4.3e-14 52.6 0.0 1.3e-13 51.1 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain C1-set PF07654.15 KFM79603.1 - 2.8e-08 34.0 0.1 0.41 11.1 0.0 4.8 5 0 0 5 5 5 3 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM79603.1 - 4.3e-08 33.3 4.4 0.032 14.5 0.1 4.7 5 0 0 5 5 4 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM79603.1 - 7.6e-08 32.7 2.0 0.032 14.6 0.1 5.0 5 0 0 5 5 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFM79603.1 - 3.9e-07 30.0 0.7 0.15 12.1 0.1 5.1 6 0 0 6 6 5 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFM79603.1 - 9.1e-07 28.9 0.0 0.11 12.6 0.1 4.2 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Pkinase_fungal PF17667.1 KFM79603.1 - 1e-05 24.6 0.0 2.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Receptor_2B4 PF11465.8 KFM79603.1 - 0.00013 22.1 0.0 17 5.7 0.0 4.7 5 0 0 5 5 5 0 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 KFM79603.1 - 0.00014 21.8 0.0 0.057 13.5 0.0 4.2 5 0 0 5 5 4 1 C17orf99 Ig domain Ig_6 PF18452.1 KFM79603.1 - 0.00024 20.6 0.1 8.8 6.0 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin domain BiPBP_C PF06832.12 KFM79603.1 - 0.0025 17.8 0.1 6 7.0 0.0 4.0 3 1 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Kdo PF06293.14 KFM79603.1 - 0.0034 16.8 0.5 0.0067 15.8 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BatD PF13584.6 KFM79603.1 - 0.0045 15.9 0.0 0.035 12.9 0.0 2.1 1 1 1 2 2 2 1 Oxygen tolerance C2-set PF05790.15 KFM79603.1 - 0.023 14.8 3.7 1.5 9.0 0.2 4.0 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Kinase-like PF14531.6 KFM79603.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KFM79603.1 - 0.054 12.5 0.3 0.14 11.2 0.3 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KFM79603.1 - 0.07 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 1 0 Phosphotransferase enzyme family zf-RRN7 PF11781.8 KFM79603.1 - 0.33 10.7 3.8 6.4 6.6 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 fn3 PF00041.21 KFM79604.1 - 2.8e-301 973.0 48.7 7.9e-19 67.8 0.2 18.9 19 0 0 19 19 18 18 Fibronectin type III domain I-set PF07679.16 KFM79604.1 - 1.3e-136 445.1 0.5 1.1e-19 70.2 0.0 13.3 15 0 0 15 15 12 8 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM79604.1 - 7.4e-75 247.6 9.7 7.8e-11 42.4 0.0 11.7 11 0 0 11 11 10 8 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM79604.1 - 5.5e-36 123.0 18.5 0.36 11.4 0.1 19.8 18 3 0 18 18 18 7 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 KFM79604.1 - 1.6e-34 118.1 2.4 0.00027 21.2 0.0 9.1 8 0 0 8 8 8 7 Immunoglobulin domain ig PF00047.25 KFM79604.1 - 1.1e-26 92.8 7.2 0.00071 19.7 0.0 9.3 9 0 0 9 9 9 6 Immunoglobulin domain V-set PF07686.17 KFM79604.1 - 7.6e-15 55.0 0.6 1.9 8.7 0.0 8.4 8 0 0 8 8 8 3 Immunoglobulin V-set domain Tissue_fac PF01108.17 KFM79604.1 - 8.9e-15 54.5 0.0 7 6.6 0.0 12.9 15 0 0 15 15 15 1 Tissue factor Y_Y_Y PF07495.13 KFM79604.1 - 1.8e-13 50.3 13.8 1.9 8.5 0.0 16.1 20 0 0 20 20 19 1 Y_Y_Y domain Receptor_2B4 PF11465.8 KFM79604.1 - 2.6e-11 43.7 2.7 1.3 9.2 0.0 8.8 8 1 1 9 9 9 2 Natural killer cell receptor 2B4 fn3_2 PF16893.5 KFM79604.1 - 2.4e-09 37.2 0.0 9.4 6.5 0.0 9.5 10 0 0 10 10 9 0 Fibronectin type III domain C2-set_2 PF08205.12 KFM79604.1 - 1e-08 35.1 7.3 0.15 12.1 0.0 6.6 6 0 0 6 6 6 1 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 KFM79604.1 - 2.1e-06 27.7 0.0 1.4 9.0 0.0 6.3 5 2 0 5 5 5 1 Penicillin-Binding Protein C-terminus Family DUF11 PF01345.18 KFM79604.1 - 2.6e-06 27.7 15.6 1.7 9.0 0.2 9.2 8 0 0 8 8 8 1 Domain of unknown function DUF11 PhoD_N PF16655.5 KFM79604.1 - 3.5e-06 27.5 0.3 13 6.4 0.0 8.1 12 0 0 12 12 7 0 PhoD-like phosphatase, N-terminal domain PA14 PF07691.12 KFM79604.1 - 6.8e-06 26.0 0.0 37 4.1 0.0 9.5 11 0 0 11 11 11 0 PA14 domain DUF2369 PF10179.9 KFM79604.1 - 1.3e-05 25.5 0.0 84 3.6 0.0 9.2 11 0 0 11 11 10 0 Uncharacterised conserved protein (DUF2369) GLEYA PF10528.9 KFM79604.1 - 8.1e-05 23.0 0.5 14 6.2 0.0 8.1 9 0 0 9 9 8 0 GLEYA domain Kelch_1 PF01344.25 KFM79604.1 - 0.014 15.0 0.5 38 4.0 0.0 4.4 4 0 0 4 4 4 0 Kelch motif MBG_2 PF18676.1 KFM79604.1 - 0.026 15.1 10.5 6.2 7.5 0.1 6.1 7 0 0 7 7 5 0 MBG domain (YGX type) TQ PF18202.1 KFM79604.1 - 0.027 15.0 0.8 45 4.6 0.0 5.7 6 0 0 6 6 3 0 T-Q ester bond containing domain TIG PF01833.24 KFM79604.1 - 0.11 12.6 0.1 3.4 7.8 0.0 3.8 3 0 0 3 3 2 0 IPT/TIG domain DUF3805 PF12712.7 KFM79604.1 - 0.15 12.2 0.0 0.46 10.6 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF3805) I-set PF07679.16 KFM79605.1 - 2.4e-189 614.0 42.5 1.8e-18 66.4 0.3 15.7 16 0 0 16 16 14 13 Immunoglobulin I-set domain fn3 PF00041.21 KFM79605.1 - 9.4e-127 413.7 7.6 6.5e-15 55.2 0.0 10.5 10 0 0 10 10 10 9 Fibronectin type III domain Ig_3 PF13927.6 KFM79605.1 - 3.3e-122 399.3 26.9 5.5e-13 49.3 0.1 14.2 13 0 0 13 13 13 13 Immunoglobulin domain ig PF00047.25 KFM79605.1 - 4.2e-73 241.6 24.2 9.1e-10 38.6 0.2 13.5 14 0 0 14 14 14 10 Immunoglobulin domain Ig_2 PF13895.6 KFM79605.1 - 1.3e-62 208.1 19.2 9.8e-09 35.4 0.0 13.6 12 1 1 13 13 13 11 Immunoglobulin domain V-set PF07686.17 KFM79605.1 - 2e-34 118.0 33.1 0.0013 18.9 2.0 16.9 13 6 0 13 13 13 9 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM79605.1 - 1.4e-13 50.7 10.3 0.052 13.6 0.0 9.2 11 0 0 11 11 8 4 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFM79605.1 - 4.2e-13 49.7 3.7 0.42 11.2 0.0 10.7 11 0 0 11 11 10 2 Purple acid Phosphatase, N-terminal domain Receptor_2B4 PF11465.8 KFM79605.1 - 1.2e-11 44.8 12.3 0.065 13.4 0.1 10.5 10 0 0 10 10 10 3 Natural killer cell receptor 2B4 Y_Y_Y PF07495.13 KFM79605.1 - 1e-10 41.4 0.3 2.6 8.1 0.0 8.5 8 0 0 8 8 8 3 Y_Y_Y domain Ig_6 PF18452.1 KFM79605.1 - 1.1e-09 37.6 0.2 0.13 11.8 0.0 6.9 7 0 0 7 7 7 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFM79605.1 - 5.3e-08 32.8 14.9 0.13 12.4 0.2 8.2 8 0 0 8 8 8 2 Izumo-like Immunoglobulin domain BiPBP_C PF06832.12 KFM79605.1 - 2.5e-05 24.3 0.0 1.8 8.7 0.0 6.2 7 1 0 7 7 6 1 Penicillin-Binding Protein C-terminus Family Ig_4 PF16680.5 KFM79605.1 - 0.00017 21.8 52.2 0.0057 16.9 1.8 11.4 9 4 1 10 10 8 3 T-cell surface glycoprotein CD3 delta chain PhoD_N PF16655.5 KFM79605.1 - 0.00038 20.9 0.0 40 4.8 0.0 6.2 6 0 0 6 6 6 0 PhoD-like phosphatase, N-terminal domain DUF11 PF01345.18 KFM79605.1 - 0.12 12.7 0.0 60 4.0 0.0 4.0 4 0 0 4 4 3 0 Domain of unknown function DUF11 PKD_3 PF16820.5 KFM79605.1 - 2.2 8.1 12.6 4.2 7.2 0.2 5.7 7 0 0 7 7 6 0 PKD-like domain I-set PF07679.16 KFM79606.1 - 2.9e-37 126.6 0.0 6.3e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM79606.1 - 1.6e-24 86.3 0.0 1.1e-11 45.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM79606.1 - 5e-14 52.4 0.0 1.1e-06 28.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM79606.1 - 2.1e-08 34.2 0.0 0.0022 18.1 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM79606.1 - 1.6e-05 24.9 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM79606.1 - 0.00019 21.5 0.0 0.023 14.8 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain BiPBP_C PF06832.12 KFM79606.1 - 0.0011 19.0 0.0 0.35 10.9 0.0 2.8 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family RRM_1 PF00076.22 KFM79607.1 - 3.9e-19 68.2 0.1 5.7e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L14 PF00238.19 KFM79608.1 - 6.1e-18 65.1 0.0 1.2e-17 64.1 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e PriA_3primeBD PF17764.1 KFM79608.1 - 0.093 12.6 0.6 0.5 10.3 0.2 2.0 1 1 1 2 2 2 0 3′ DNA-binding domain (3′BD) zf-C3HC4_3 PF13920.6 KFM79609.1 - 1.1e-11 44.4 8.3 1.1e-11 44.4 8.3 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM79609.1 - 0.00036 20.3 8.9 0.00036 20.3 8.9 3.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.21 KFM79609.1 - 0.46 10.7 32.7 8 6.7 28.6 3.8 1 1 1 2 2 2 0 FYVE zinc finger zf-C3HC4_2 PF13923.6 KFM79609.1 - 0.61 10.0 26.5 0.72 9.8 11.5 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM79609.1 - 2.9 7.9 36.6 0.065 13.2 9.6 3.6 3 1 0 3 3 3 0 zinc-RING finger domain Sec7 PF01369.20 KFM79611.1 - 2e-65 219.9 1.4 2.5e-65 219.6 0.4 1.6 2 0 0 2 2 2 1 Sec7 domain IQ_SEC7_PH PF16453.5 KFM79611.1 - 8.6e-65 216.9 0.5 2.4e-64 215.5 0.5 1.8 1 0 0 1 1 1 1 PH domain IQ PF00612.27 KFM79611.1 - 0.069 13.0 5.1 0.069 13.0 3.0 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif Sugar_tr PF00083.24 KFM79612.1 - 1.5e-78 264.7 24.1 1.8e-78 264.5 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM79612.1 - 5.7e-30 104.4 60.1 1.6e-25 89.8 37.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily XhlA PF10779.9 KFM79612.1 - 1.7 8.9 3.5 5.5 7.3 3.5 1.9 1 0 0 1 1 1 0 Haemolysin XhlA TPR_19 PF14559.6 KFM79613.1 - 1.1e-31 109.1 29.2 8.3e-07 29.4 0.2 10.2 7 3 3 10 10 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 KFM79613.1 - 7.3e-26 88.6 13.2 0.0046 17.7 0.0 14.5 10 3 7 17 17 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFM79613.1 - 2.4e-21 74.0 53.9 0.00011 22.0 0.1 17.3 21 0 0 21 21 18 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFM79613.1 - 2.1e-16 59.0 43.1 9.8e-07 28.3 0.1 14.9 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFM79613.1 - 3.3e-16 59.6 8.6 0.0001 22.8 0.0 9.0 8 2 1 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM79613.1 - 9.7e-15 54.0 6.4 0.00023 20.8 0.1 9.7 8 1 2 10 10 10 2 TPR repeat TPR_12 PF13424.6 KFM79613.1 - 5.3e-13 49.1 30.3 0.002 18.3 0.1 12.2 12 3 1 13 13 13 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFM79613.1 - 2.7e-11 43.0 4.0 0.037 14.4 0.0 9.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM79613.1 - 3.4e-11 42.4 57.5 0.00058 19.9 0.1 14.7 18 0 0 18 18 14 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFM79613.1 - 9.1e-10 37.9 10.7 0.0031 17.4 0.0 9.0 11 1 1 12 12 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFM79613.1 - 4.8e-07 29.3 10.4 0.23 10.6 0.1 7.0 3 1 0 6 6 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 KFM79613.1 - 8.5e-07 28.9 13.2 0.21 11.2 0.3 6.1 3 2 3 6 6 6 3 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 KFM79613.1 - 2.2e-06 27.3 11.2 0.024 14.0 0.5 5.6 4 2 2 6 6 5 2 MalT-like TPR region ANAPC3 PF12895.7 KFM79613.1 - 6.7e-06 26.2 27.8 0.13 12.5 0.6 8.0 6 3 4 10 10 9 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFM79613.1 - 6.8e-06 26.4 20.2 0.06 14.0 0.1 11.5 15 0 0 15 15 11 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFM79613.1 - 5.6e-05 23.4 10.7 0.058 13.7 0.2 7.2 5 2 2 7 7 7 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KFM79613.1 - 0.0012 18.5 0.9 5.3 6.7 0.0 4.8 4 0 0 4 4 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 KFM79613.1 - 0.0015 19.0 0.3 40 5.3 0.3 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFM79613.1 - 0.0024 18.0 5.7 4.5 7.5 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM79613.1 - 0.0027 17.5 9.2 1.6 8.7 0.0 7.8 10 0 0 10 10 7 1 Tetratricopeptide repeat MIT PF04212.18 KFM79613.1 - 0.01 15.9 6.0 11 6.2 0.2 5.9 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain PknG_TPR PF16918.5 KFM79613.1 - 0.015 14.1 0.9 3.9 6.1 0.1 3.4 4 1 1 5 5 5 0 Protein kinase G tetratricopeptide repeat ImpA_N PF06812.12 KFM79613.1 - 0.054 13.6 1.4 19 5.4 0.1 3.7 4 0 0 4 4 4 0 ImpA, N-terminal, type VI secretion system SRP_TPR_like PF17004.5 KFM79613.1 - 0.1 12.6 12.2 23 5.1 0.0 5.4 5 0 0 5 5 5 0 Putative TPR-like repeat ANAPC5 PF12862.7 KFM79613.1 - 0.12 12.4 1.2 4.4 7.4 0.7 3.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 KFM79614.1 - 3.9e-08 32.8 5.5 0.0026 17.7 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM79614.1 - 2.6e-06 27.0 6.0 0.0031 17.3 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM79614.1 - 3e-06 27.7 0.0 4.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM79614.1 - 3.3e-05 24.4 0.0 0.075 13.9 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM79614.1 - 3.4e-05 24.2 2.5 0.004 17.7 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM79614.1 - 0.00027 20.9 5.0 0.0079 16.3 1.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 KFM79614.1 - 0.0012 18.8 3.1 0.42 10.7 0.2 2.5 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 KFM79614.1 - 0.0026 18.0 0.0 2.5 8.4 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM79614.1 - 0.0041 17.7 0.0 0.027 15.1 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM79614.1 - 0.023 14.7 0.2 0.72 10.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM79614.1 - 0.067 13.3 1.2 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MFS_1 PF07690.16 KFM79616.1 - 5.2e-36 124.3 27.3 5.2e-36 124.3 27.3 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KFM79616.1 - 1.6e-16 59.8 23.4 3.4e-06 25.6 2.7 4.1 2 2 2 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KFM79616.1 - 1.4e-10 40.7 6.5 1.4e-10 40.7 6.5 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.6 KFM79616.1 - 0.0038 15.8 6.6 0.0038 15.8 6.6 2.4 1 1 1 2 2 2 1 MFS/sugar transport protein TMEM43 PF07787.12 KFM79616.1 - 3.9 6.8 4.5 21 4.4 1.4 2.6 2 0 0 2 2 2 0 Transmembrane protein 43 TMPIT PF07851.13 KFM79617.1 - 1e-99 333.9 20.1 1.1e-99 333.7 20.1 1.0 1 0 0 1 1 1 1 TMPIT-like protein DUF4079 PF13301.6 KFM79617.1 - 2.9 8.1 7.3 0.32 11.1 0.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) RINGv PF12906.7 KFM79618.1 - 2.3e-15 56.4 13.9 5.4e-15 55.2 13.9 1.7 1 0 0 1 1 1 1 RING-variant domain 7tm_7 PF08395.12 KFM79618.1 - 0.0036 16.6 1.9 0.0063 15.8 1.9 1.3 1 0 0 1 1 1 1 7tm Chemosensory receptor DctQ PF04290.12 KFM79618.1 - 0.067 13.1 1.6 0.1 12.5 1.6 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component zf-RING_2 PF13639.6 KFM79618.1 - 2.1 8.7 16.9 1.1 9.7 13.8 2.1 2 0 0 2 2 2 0 Ring finger domain Sec23_trunk PF04811.15 KFM79619.1 - 7.2e-71 238.6 0.0 1.2e-70 237.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFM79619.1 - 3.5e-26 91.0 0.3 7.1e-26 90.0 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFM79619.1 - 7e-18 65.2 0.0 1.7e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFM79619.1 - 1.2e-12 47.6 4.4 1.2e-12 47.6 4.4 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFM79619.1 - 3.7e-10 39.6 0.0 9.1e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat GDP_Man_Dehyd PF16363.5 KFM79619.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HMG_box PF00505.19 KFM79621.1 - 8.3e-16 58.2 0.2 1.8e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM79621.1 - 1e-09 38.9 0.7 3e-09 37.3 0.2 2.1 2 0 0 2 2 2 1 HMG-box domain Dynein_C PF18199.1 KFM79622.1 - 4.4e-15 55.7 0.0 4.7e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain SHP PF03579.13 KFM79625.1 - 0.0032 17.4 1.1 0.0052 16.7 0.1 1.9 2 0 0 2 2 2 1 Small hydrophobic protein Itfg2 PF15907.5 KFM79628.1 - 1.5e-117 392.4 0.0 2.3e-116 388.5 0.0 1.9 2 0 0 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 KFM79628.1 - 1.1e-10 41.5 0.1 0.055 13.5 0.0 3.4 3 0 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 KFM79628.1 - 5.2e-06 27.0 3.4 1.6 9.4 0.2 3.9 2 1 3 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS1 PF14779.6 KFM79628.1 - 4.1e-05 23.2 0.0 0.0076 15.7 0.0 2.5 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.6 KFM79628.1 - 0.0036 16.7 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 2 PTHB1 N-terminus FG-GAP PF01839.23 KFM79628.1 - 0.017 15.2 7.5 0.84 9.8 1.8 2.7 2 0 0 2 2 2 0 FG-GAP repeat BBS2_C PF14782.6 KFM79628.1 - 0.02 13.7 0.0 3.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal THAP PF05485.12 KFM79629.1 - 4e-16 59.7 3.2 7e-16 58.9 3.2 1.4 1 0 0 1 1 1 1 THAP domain AMPK1_CBM PF16561.5 KFM79630.1 - 1.8e-22 79.3 0.5 3.1e-22 78.6 0.5 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KFM79630.1 - 0.04 14.3 3.6 0.066 13.6 0.0 3.2 2 1 2 4 4 4 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Myotub-related PF06602.14 KFM79633.1 - 0.00027 20.0 0.3 0.00057 18.9 0.3 1.7 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KFM79633.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4902 PF16245.5 KFM79633.1 - 0.16 11.8 0.5 0.34 10.8 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4902) zf-H2C2_2 PF13465.6 KFM79634.1 - 3.9e-88 286.3 75.3 2.4e-09 37.2 1.2 12.9 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79634.1 - 7.5e-60 196.2 94.5 2.2e-05 24.6 1.2 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79634.1 - 1e-43 144.2 90.5 0.0005 20.7 0.8 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM79634.1 - 3.8e-27 93.8 82.9 0.038 14.4 0.7 12.4 12 0 0 12 12 12 12 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM79634.1 - 5.6e-23 80.4 72.6 0.034 14.2 0.3 12.6 12 0 0 12 12 12 11 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM79634.1 - 6.9e-19 67.3 61.2 0.2 11.5 0.3 12.5 12 0 0 12 12 12 9 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM79634.1 - 1.7e-17 63.2 55.8 0.14 12.5 0.3 12.3 12 0 0 12 12 12 9 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM79634.1 - 6.4e-08 32.3 24.3 0.82 9.5 0.0 9.5 2 2 8 11 11 11 2 GAGA factor zf-C2H2_9 PF16293.5 KFM79634.1 - 1.1e-07 31.5 48.9 0.71 9.8 0.1 11.6 2 2 10 12 12 12 4 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM79634.1 - 1.8e-05 24.9 8.9 5.2 7.4 0.0 6.6 2 2 4 6 6 6 1 BolA-like protein ADK_lid PF05191.14 KFM79634.1 - 8.4e-05 22.5 31.6 0.59 10.2 0.4 7.8 3 3 6 9 9 9 2 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM79634.1 - 0.00014 22.0 0.3 15 5.8 0.0 5.0 1 1 3 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Complex1_49kDa PF00346.19 KFM79634.1 - 0.0014 17.8 0.7 3.5 6.6 0.0 3.7 1 1 3 4 4 4 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF4825 PF16107.5 KFM79634.1 - 0.0021 18.2 0.1 17 5.6 0.0 5.1 2 1 2 5 5 5 0 Domain of unknown function (DUF4825) C1_4 PF07975.12 KFM79634.1 - 0.0037 17.5 62.7 0.29 11.4 3.1 8.2 1 1 6 9 9 9 2 TFIIH C1-like domain FYVE PF01363.21 KFM79634.1 - 0.012 15.7 65.3 1.6 9.0 10.8 6.7 3 3 2 5 5 5 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFM79634.1 - 0.027 15.2 48.0 1.9 9.3 1.0 6.2 2 1 2 6 6 6 0 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM79634.1 - 0.045 13.8 49.4 2.1 8.5 10.9 5.1 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_2 PF12756.7 KFM79634.1 - 0.053 13.9 78.6 6.1 7.2 0.8 11.4 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 KFM79634.1 - 0.2 11.8 60.6 3.5 7.8 0.9 11.5 1 1 9 11 11 11 0 KIAA1045 RING finger zf-C2HC_2 PF13913.6 KFM79634.1 - 0.72 9.8 52.8 2.4 8.1 0.5 11.8 12 0 0 12 12 12 0 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM79634.1 - 0.8 9.9 48.8 10 6.3 0.2 10.9 12 0 0 12 12 12 0 DBF zinc finger zf-Sec23_Sec24 PF04810.15 KFM79634.1 - 1.9 8.6 48.9 2.2 8.4 0.1 11.4 6 4 4 10 10 10 0 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM79634.1 - 3.4 7.4 53.6 5.5 6.7 0.1 11.2 4 3 8 12 12 12 0 MYST family zinc finger domain zf-CHCC PF10276.9 KFM79634.1 - 5.5 7.1 22.6 73 3.5 0.0 9.1 11 0 0 11 11 11 0 Zinc-finger domain eIF_4EBP PF05456.11 KFM79635.1 - 1.7e-44 150.4 1.0 1.9e-44 150.3 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Alpha-2-MRAP_C PF06401.11 KFM79636.1 - 2.4e-53 181.3 22.2 2.4e-53 181.3 22.2 2.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.11 KFM79636.1 - 1.7e-42 144.1 21.2 9.9e-36 122.3 4.1 3.4 3 1 0 3 3 3 3 Alpha-2-macroglobulin RAP, N-terminal domain DUF4476 PF14771.6 KFM79636.1 - 0.012 15.9 2.1 5.7 7.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4476) DUF2407_C PF13373.6 KFM79636.1 - 0.077 13.2 0.7 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF5053 PF16476.5 KFM79636.1 - 0.078 12.7 2.0 5.4 6.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5053) Uds1 PF15456.6 KFM79636.1 - 0.12 12.5 8.6 13 5.9 0.3 3.4 2 1 1 3 3 3 0 Up-regulated During Septation U3_assoc_6 PF08640.11 KFM79636.1 - 0.72 10.0 7.7 0.19 11.8 4.1 2.0 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 DUF2730 PF10805.8 KFM79636.1 - 1.8 8.7 11.6 15 5.8 0.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) FAM176 PF14851.6 KFM79638.1 - 0.026 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.15 KFM79638.1 - 0.25 12.0 1.4 0.46 11.1 1.4 1.4 1 1 0 1 1 1 0 Ctr copper transporter family Sid-5 PF17204.3 KFM79638.1 - 0.3 11.3 1.0 0.78 10.0 0.1 1.9 1 1 1 2 2 2 0 Sid-5 family DUF3619 PF12279.8 KFM79638.1 - 0.8 10.0 3.7 0.33 11.3 1.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) ubiquitin PF00240.23 KFM79639.1 - 1.1e-11 44.4 0.0 1.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFM79639.1 - 1.2e-05 25.8 0.0 1.3e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFM79639.1 - 0.0063 16.6 0.0 0.0085 16.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SHQ1 PF04925.15 KFM79639.1 - 0.023 14.2 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 SHQ1 protein Mito_carr PF00153.27 KFM79640.1 - 1.6e-12 47.1 0.0 6.9e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein SepSecS PF05889.13 KFM79641.1 - 2.3e-128 428.2 0.0 2.8e-128 427.9 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 KFM79641.1 - 1.4e-07 31.2 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Put_Phosphatase PF06888.12 KFM79642.1 - 6.3e-60 202.5 0.0 7.3e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KFM79642.1 - 0.0033 17.9 0.0 0.0072 16.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase COR PF16095.5 KFM79642.1 - 0.045 13.6 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain DUF19 PF01579.18 KFM79644.1 - 0.13 12.0 16.2 0.1 12.4 14.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF19) PDZ PF00595.24 KFM79645.1 - 3.2e-10 40.2 0.0 7.3e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM79645.1 - 3.7e-10 39.5 0.0 6.1e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM79645.1 - 0.00014 22.1 0.0 0.00041 20.6 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Caskin-Pro-rich PF16907.5 KFM79645.1 - 0.0081 16.7 0.3 0.0081 16.7 0.3 3.0 3 0 0 3 3 3 1 Proline rich region of Caskin proteins FtsL PF04999.13 KFM79645.1 - 0.0098 15.9 1.2 0.022 14.8 1.2 1.5 1 0 0 1 1 1 1 Cell division protein FtsL HDAC4_Gln PF12203.8 KFM79645.1 - 0.61 10.3 4.8 1.6 9.0 0.1 2.5 2 0 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 MAP7 PF05672.11 KFM79645.1 - 1.7 8.3 15.0 3.7 7.2 15.0 1.6 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family PDZ PF00595.24 KFM79646.1 - 1.3e-16 60.7 0.0 1.9e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM79646.1 - 6.5e-09 35.5 0.0 9.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM79646.1 - 2.1e-05 24.8 0.0 2.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 PDZ domain NAAA-beta PF15508.6 KFM79647.1 - 0.073 13.4 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AA_permease_2 PF13520.6 KFM79648.1 - 7.1e-27 94.3 23.0 7.9e-27 94.1 23.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM79648.1 - 4.7e-11 41.9 20.6 5.5e-11 41.7 20.6 1.0 1 0 0 1 1 1 1 Amino acid permease SirB PF04247.12 KFM79648.1 - 0.32 11.1 8.5 3.2 7.9 3.9 2.6 2 1 0 2 2 2 0 Invasion gene expression up-regulator, SirB DRY_EERY PF09750.9 KFM79649.1 - 5.4 7.3 9.0 3.2 8.0 5.9 2.2 2 0 0 2 2 2 0 Alternative splicing regulator Peptidase_C1 PF00112.23 KFM79650.1 - 3.7e-64 216.8 0.1 6e-64 216.1 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM79650.1 - 2.7e-08 34.1 0.2 4.8e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) zf-RING_2 PF13639.6 KFM79654.1 - 7e-12 45.5 12.6 1.3e-11 44.6 12.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFM79654.1 - 7.2e-09 35.2 5.0 7.2e-09 35.2 5.0 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFM79654.1 - 1.2e-07 31.4 11.2 2.4e-07 30.5 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM79654.1 - 2.1e-07 30.8 4.3 2.1e-07 30.8 4.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFM79654.1 - 3.5e-06 27.2 13.5 1.4e-05 25.3 13.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM79654.1 - 7.5e-06 25.7 12.0 1.6e-05 24.6 12.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM79654.1 - 1.3e-05 25.0 9.7 2.4e-05 24.2 9.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFM79654.1 - 5e-05 23.3 4.8 0.00011 22.2 4.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFM79654.1 - 0.00015 21.5 9.0 0.00028 20.7 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFM79654.1 - 0.0059 16.2 8.3 0.011 15.3 8.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFM79654.1 - 0.07 13.3 10.0 0.26 11.5 10.0 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2H2_6 PF13912.6 KFM79654.1 - 0.48 10.5 4.1 1.8 8.6 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Prok-RING_4 PF14447.6 KFM79654.1 - 1.4 8.9 10.0 3.5 7.6 10.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFM79654.1 - 8.7 6.2 11.0 29 4.6 11.0 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain CLTH PF10607.9 KFM79655.1 - 1.5e-35 122.3 0.6 1.4e-34 119.2 0.2 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KFM79655.1 - 5.7e-06 26.3 0.2 1.2e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KFM79655.1 - 0.00089 18.7 0.1 0.0016 17.9 0.1 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KFM79655.1 - 0.0065 16.8 0.3 0.019 15.3 0.3 1.9 1 0 0 1 1 1 1 Ring finger domain ZnuA PF01297.17 KFM79655.1 - 0.13 11.6 0.2 0.49 9.7 0.2 2.1 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic zf-RING_5 PF14634.6 KFM79655.1 - 0.22 11.5 1.1 0.4 10.7 0.4 1.8 2 0 0 2 2 2 0 zinc-RING finger domain p450 PF00067.22 KFM79656.1 - 9.2e-81 271.9 0.0 1.1e-80 271.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Biliv-reduc_cat PF09166.10 KFM79656.1 - 0.029 14.7 0.1 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Biliverdin reductase, catalytic Ank_4 PF13637.6 KFM79658.1 - 1.6e-06 28.5 0.0 1.9e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM79658.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM79658.1 - 0.00046 20.5 0.0 0.89 10.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFM79658.1 - 0.00052 20.5 0.0 0.00075 20.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM79658.1 - 0.0022 18.3 0.1 1.2 9.9 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFM79659.1 - 3.9e-06 27.4 0.1 4.8e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM79659.1 - 0.00099 19.5 0.2 1.2 9.7 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFM79659.1 - 0.002 18.5 0.1 6.5 7.7 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFM79659.1 - 0.069 13.5 0.1 0.41 11.0 0.0 2.1 2 1 0 2 2 2 0 Ankyrin repeats (many copies) HNOB PF07700.15 KFM79659.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Haem-NO-binding Cas_Csy4 PF09618.10 KFM79659.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Ank_2 PF12796.7 KFM79660.1 - 6.7e-14 52.2 6.4 1.3e-07 32.1 1.2 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFM79660.1 - 1.3e-09 38.1 0.1 1.6e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFM79660.1 - 1e-06 29.1 0.1 5.5e-05 23.6 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM79660.1 - 2.7e-06 27.3 0.5 0.029 14.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFM79660.1 - 4.2e-05 23.7 1.0 0.00034 20.9 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) 3-HAO PF06052.12 KFM79662.1 - 1.3e-35 122.3 0.0 9.3e-34 116.2 0.0 2.1 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KFM79662.1 - 0.00016 21.3 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding_2 PF14525.6 KFM79662.1 - 0.00084 19.1 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 AraC-binding-like domain AraC_binding PF02311.19 KFM79662.1 - 0.031 14.2 0.0 3.8 7.4 0.0 2.5 2 1 0 2 2 2 0 AraC-like ligand binding domain Peptidase_C1 PF00112.23 KFM79663.1 - 4.7e-88 294.9 4.4 6.3e-88 294.5 4.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM79663.1 - 6.3e-09 36.1 0.2 1.2e-08 35.3 0.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM79663.1 - 2.5e-05 23.3 1.8 0.015 14.1 0.5 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Meiosis_expr PF15163.6 KFM79663.1 - 0.17 12.5 0.3 0.71 10.6 0.1 2.1 2 0 0 2 2 2 0 Meiosis-expressed Cystatin PF00031.21 KFM79664.1 - 4.8e-16 58.8 0.0 5.5e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFM79664.1 - 0.00076 19.8 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor Kunitz_BPTI PF00014.23 KFM79665.1 - 4.4e-36 122.9 23.2 5.4e-19 68.2 5.2 3.0 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain DNA_pol_A_exo1 PF01612.20 KFM79666.1 - 1.4e-20 73.8 0.2 3.6e-20 72.4 0.2 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Mut7-C PF01927.16 KFM79666.1 - 6.8e-10 39.2 0.3 4.6e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 Mut7-C RNAse domain Dynamin_M PF01031.20 KFM79669.1 - 3.3e-64 216.9 1.3 6.3e-64 215.9 1.3 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFM79669.1 - 4.7e-56 189.4 0.1 4.7e-55 186.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFM79669.1 - 8.4e-05 22.6 0.0 0.00035 20.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KFM79669.1 - 0.13 12.5 0.4 1.4 9.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain Dynamin_M PF01031.20 KFM79670.1 - 8.8e-31 107.2 1.2 8.8e-31 107.2 1.2 1.8 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 KFM79670.1 - 1e-22 80.1 2.7 1e-22 80.1 2.7 1.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain PH PF00169.29 KFM79670.1 - 1.3e-11 45.0 0.3 2.1e-11 44.2 0.3 1.4 1 0 0 1 1 1 1 PH domain ApoO PF09769.9 KFM79670.1 - 0.16 11.9 0.0 0.47 10.4 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein O PH_11 PF15413.6 KFM79670.1 - 0.32 11.4 1.5 5.5 7.5 1.5 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain CDC73_C PF05179.14 KFM79671.1 - 2.8e-07 30.4 0.1 3.2e-07 30.2 0.1 1.0 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KFM79672.1 - 2.5e-39 135.4 1.6 3.4e-39 134.9 1.6 1.2 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 KFM79672.1 - 8.8e-18 64.5 0.0 1.8e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Cullin PF00888.22 KFM79673.1 - 7.6e-195 649.1 10.6 7.6e-195 649.1 10.6 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KFM79673.1 - 4.1e-19 68.4 6.5 1.1e-18 67.0 6.5 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Stork_head PF10264.9 KFM79673.1 - 0.024 14.8 0.8 0.079 13.1 0.8 1.9 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain zf-C2H2 PF00096.26 KFM79677.1 - 7.4e-18 63.9 20.4 6.5e-05 23.2 1.0 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM79677.1 - 1.9e-15 56.5 24.3 0.00012 22.4 0.2 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM79677.1 - 9.7e-15 54.0 18.6 0.0021 18.7 0.5 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFM79677.1 - 1.6e-08 34.8 9.7 0.00088 19.5 3.7 3.2 1 1 0 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFM79677.1 - 2.5e-07 30.8 5.4 0.7 10.3 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFM79677.1 - 0.00027 21.2 11.9 0.75 9.9 0.2 4.0 1 1 3 4 4 4 3 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFM79677.1 - 0.0006 19.7 19.5 0.24 11.5 0.5 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf_Hakai PF18408.1 KFM79677.1 - 0.001 18.7 16.6 0.047 13.4 0.3 3.8 4 0 0 4 4 4 2 C2H2 Hakai zinc finger domain zf_ZIC PF18366.1 KFM79677.1 - 0.0043 17.1 7.8 12 6.1 0.0 4.3 4 0 0 4 4 4 1 Zic proteins zinc finger domain CHORD PF04968.12 KFM79677.1 - 0.086 13.6 14.4 7.1 7.4 0.1 4.1 1 1 3 4 4 4 0 CHORD PcF PF09461.10 KFM79677.1 - 0.25 11.7 8.1 10 6.6 0.2 3.7 4 0 0 4 4 4 0 Phytotoxin PcF protein VKOR PF07884.14 KFM79677.1 - 0.88 9.8 2.9 3.6 7.8 0.2 2.5 1 1 2 3 3 3 0 Vitamin K epoxide reductase family zf-C2H2_11 PF16622.5 KFM79677.1 - 3.4 7.5 9.3 3.2 7.6 0.3 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type Ribosomal_S4e PF00900.20 KFM79678.1 - 9.1e-37 124.8 0.1 2.6e-36 123.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KFM79678.1 - 5.6e-23 80.3 0.0 1.1e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KFM79678.1 - 1e-21 76.7 4.6 2.1e-21 75.7 4.6 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KFM79678.1 - 2e-09 37.0 0.1 5.3e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 KFM79678.1 - 4.1e-07 29.7 0.6 1.4e-06 28.1 0.6 2.0 1 0 0 1 1 1 1 KOW motif Taxilin PF09728.9 KFM79680.1 - 5.8e-94 314.7 63.6 5.8e-94 314.7 63.6 1.6 1 1 0 1 1 1 1 Myosin-like coiled-coil protein ZapB PF06005.12 KFM79680.1 - 0.031 14.7 5.3 0.031 14.7 5.3 7.0 2 2 2 5 5 5 0 Cell division protein ZapB APG6_N PF17675.1 KFM79680.1 - 1.2 9.6 69.6 0.23 12.0 17.9 5.0 1 1 3 4 4 4 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KFM79680.1 - 3.7 7.7 66.8 0.2 11.9 29.4 4.0 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 Choline_transpo PF04515.12 KFM79681.1 - 1.1e-100 337.0 30.9 1.1e-100 337.0 30.9 3.4 3 1 0 3 3 3 1 Plasma-membrane choline transporter MaAIMP_sms PF16951.5 KFM79681.1 - 0.098 12.4 3.8 3.5 7.4 1.8 3.0 2 0 0 2 2 2 0 Putative methionine and alanine importer, small subunit CBM_14 PF01607.24 KFM79682.1 - 2.9e-37 126.6 26.3 8.5e-13 48.3 5.3 3.2 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain v110 PF01639.17 KFM79682.1 - 0.2 11.5 0.1 0.2 11.5 0.1 2.5 2 1 0 2 2 2 0 Viral family 110 CBM_14 PF01607.24 KFM79683.1 - 2.3e-27 94.9 30.2 3.9e-10 39.7 1.9 3.6 3 1 0 3 3 3 3 Chitin binding Peritrophin-A domain SMC_N PF02463.19 KFM79684.1 - 1.6e-32 112.8 18.6 6.4e-32 110.8 16.7 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KFM79684.1 - 5.8e-14 52.6 15.9 6.4e-13 49.2 15.9 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KFM79684.1 - 3.2e-09 37.6 51.9 0.0022 18.5 51.9 3.6 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KFM79684.1 - 0.00015 21.7 0.8 0.00015 21.7 0.8 2.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM79684.1 - 0.00029 20.5 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KxDL PF10241.9 KFM79684.1 - 0.00052 20.2 2.2 0.00052 20.2 2.2 4.3 4 0 0 4 4 4 2 Uncharacterized conserved protein FPP PF05911.11 KFM79684.1 - 0.3 9.2 46.9 0.013 13.7 33.8 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil PKcGMP_CC PF16808.5 KFM79684.1 - 1.5 8.7 21.4 2 8.3 1.5 4.3 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PE PF00934.20 KFM79684.1 - 3.3 8.1 5.6 1.4 9.3 2.3 2.0 2 0 0 2 2 2 0 PE family DUF4472 PF14739.6 KFM79684.1 - 3.7 8.3 45.2 0.15 12.8 3.1 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4472) Fez1 PF06818.15 KFM79684.1 - 4.6 7.6 44.5 1.5 9.2 20.5 3.0 1 1 1 2 2 2 0 Fez1 ANF_receptor PF01094.28 KFM79685.1 - 1.7e-08 33.9 0.0 1.9e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region LSM PF01423.22 KFM79686.1 - 1.4e-18 66.3 0.6 1.8e-18 66.0 0.6 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFM79686.1 - 0.0095 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Gemin7 PF11095.8 KFM79686.1 - 0.016 15.1 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.6 KFM79686.1 - 0.052 13.7 0.1 0.07 13.3 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain TM2 PF05154.16 KFM79687.1 - 1.1e-15 57.7 4.2 2e-15 56.8 4.2 1.4 1 0 0 1 1 1 1 TM2 domain MFS_5 PF05631.14 KFM79688.1 - 3.5e-91 305.8 15.6 4.7e-91 305.3 15.6 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KFM79688.1 - 1.1e-16 60.8 30.2 1.1e-16 60.8 30.2 2.6 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF4044 PF13253.6 KFM79688.1 - 2 8.0 8.1 0.066 12.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) TGF_beta PF00019.20 KFM79689.1 - 3e-31 108.5 0.3 6.1e-31 107.5 0.3 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFM79689.1 - 1.6e-21 77.2 1.1 2.7e-20 73.2 1.2 2.1 1 1 0 1 1 1 1 TGF-beta propeptide zf-C2H2_2 PF12756.7 KFM79690.1 - 3.1e-31 107.7 19.0 2e-26 92.3 3.8 3.4 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFM79690.1 - 1.5e-08 34.7 29.4 1.7e-08 34.5 4.2 4.2 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM79690.1 - 5.5e-08 32.9 14.2 8.2e-07 29.2 4.3 3.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM79690.1 - 0.0038 17.9 1.0 0.0038 17.9 1.0 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-UBP PF02148.19 KFM79690.1 - 0.0066 16.8 0.8 0.0066 16.8 0.8 4.1 5 0 0 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein c-SKI_SMAD_bind PF08782.10 KFM79690.1 - 0.019 15.2 6.4 0.044 14.0 0.1 3.0 3 0 0 3 3 3 0 c-SKI Smad4 binding domain FOXP-CC PF16159.5 KFM79690.1 - 0.15 12.7 0.4 0.15 12.7 0.4 2.8 4 0 0 4 4 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KFM79690.1 - 0.17 12.4 15.2 0.074 13.5 2.5 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-BED PF02892.15 KFM79690.1 - 0.28 11.2 12.0 0.27 11.3 0.4 3.6 3 0 0 3 3 3 0 BED zinc finger SCIMP PF15050.6 KFM79690.1 - 0.52 10.8 0.1 0.52 10.8 0.1 2.0 2 1 1 3 3 3 0 SCIMP protein Astro_capsid_p PF12226.8 KFM79690.1 - 0.84 8.7 4.9 1.4 8.0 4.9 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Codanin-1_C PF15296.6 KFM79691.1 - 1.2e-25 89.9 0.2 2.1e-25 89.1 0.2 1.4 1 0 0 1 1 1 1 Codanin-1 C-terminus 5HT_transport_N PF03491.13 KFM79692.1 - 3 8.1 10.0 4.6 7.5 0.1 4.0 1 1 3 4 4 4 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Ig_3 PF13927.6 KFM79693.1 - 3.2e-09 37.2 0.0 5.1e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM79693.1 - 3.6e-08 33.6 0.0 1.4e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM79693.1 - 3.5e-07 30.3 0.0 3.9e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM79693.1 - 8.1e-06 26.0 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFM79693.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_4 PF16680.5 KFM79693.1 - 0.076 13.3 0.0 2.3 8.5 0.0 2.1 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain RRM_1 PF00076.22 KFM79694.1 - 5.9e-09 35.6 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP PF17069.5 KFM79694.1 - 8.5 5.9 55.3 2.7 7.5 9.9 2.5 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 MtN3_slv PF03083.16 KFM79695.1 - 3.9e-43 145.4 19.6 3.4e-25 87.9 1.4 2.5 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange NnrS PF05940.12 KFM79695.1 - 0.0087 15.5 6.2 0.098 12.0 2.5 2.1 1 1 1 2 2 2 2 NnrS protein PQ-loop PF04193.14 KFM79695.1 - 0.08 12.7 0.1 0.08 12.7 0.1 4.5 3 2 1 4 4 4 0 PQ loop repeat DUF2304 PF10066.9 KFM79695.1 - 2.7 8.2 9.6 1.9 8.8 0.2 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) RPN6_N PF18055.1 KFM79696.1 - 9.8e-30 103.3 0.5 9.8e-30 103.3 0.5 2.1 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KFM79696.1 - 2.2e-19 69.9 0.5 6.8e-19 68.3 0.2 2.0 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.6 KFM79696.1 - 0.00068 19.9 7.9 0.044 14.1 0.8 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM79696.1 - 0.0052 16.2 2.4 0.0083 15.5 0.6 2.1 2 1 0 2 2 2 1 MalT-like TPR region EamA PF00892.20 KFM79697.1 - 4.8e-09 36.5 0.7 5.7e-09 36.3 0.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family Nuc_sug_transp PF04142.15 KFM79697.1 - 1.6e-08 34.1 0.0 1.7e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 KFM79697.1 - 1.1e-07 31.2 0.1 1.3e-07 30.9 0.1 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KFM79697.1 - 2.9e-05 23.6 0.1 3e-05 23.5 0.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 KFM79697.1 - 0.00016 21.3 0.0 0.00017 21.2 0.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 KFM79697.1 - 0.0015 17.8 0.3 0.0018 17.6 0.3 1.0 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport DUF3522 PF12036.8 KFM79697.1 - 0.13 12.6 2.9 1.6 9.0 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) zf-H2C2_2 PF13465.6 KFM79698.1 - 1.3e-114 370.0 103.5 1.3e-10 41.2 0.3 16.1 16 0 0 16 16 16 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79698.1 - 2e-77 251.5 125.9 1.5e-06 28.4 0.2 15.1 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79698.1 - 4.6e-53 173.3 119.4 0.00092 19.9 1.1 15.1 15 0 0 15 15 15 15 C2H2-type zinc finger zf-met PF12874.7 KFM79698.1 - 6.1e-45 150.4 119.1 0.0006 20.1 1.0 15.2 15 0 0 15 15 15 14 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM79698.1 - 7.9e-23 79.9 101.2 0.0002 21.3 0.2 15.2 15 0 0 15 15 15 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM79698.1 - 5.3e-20 71.2 84.0 0.055 13.8 0.3 15.7 15 0 0 15 15 15 10 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM79698.1 - 2.8e-15 55.7 84.7 0.13 12.0 0.7 15.3 15 0 0 15 15 15 10 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM79698.1 - 8.3e-14 51.3 45.4 0.052 13.5 0.2 9.6 4 1 7 11 11 11 8 Adenylate kinase, active site lid BolA PF01722.18 KFM79698.1 - 4.7e-10 39.6 21.9 0.57 10.5 0.1 7.6 1 1 6 7 7 7 5 BolA-like protein Tox-HNH-HHH PF15637.6 KFM79698.1 - 2.1e-09 37.5 11.3 0.96 9.6 0.0 7.1 1 1 7 8 8 8 3 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2HC_2 PF13913.6 KFM79698.1 - 5.3e-08 32.6 59.4 1.3 9.0 0.1 14.2 14 0 0 14 14 14 5 zinc-finger of a C2HC-type zf-CHCC PF10276.9 KFM79698.1 - 2.6e-05 24.2 21.7 24 5.1 0.0 12.3 15 0 0 15 15 14 0 Zinc-finger domain FYVE PF01363.21 KFM79698.1 - 3e-05 24.1 76.8 0.087 13.0 10.0 8.2 1 1 4 6 6 5 1 FYVE zinc finger DUF2256 PF10013.9 KFM79698.1 - 4e-05 23.6 52.6 39 4.5 0.0 14.7 15 0 0 15 15 15 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 KFM79698.1 - 0.00013 21.6 78.5 1 9.2 0.2 14.1 15 0 0 15 15 14 5 zinc-finger C2H2-type zf-DBF PF07535.12 KFM79698.1 - 0.0051 16.9 58.3 9.5 6.4 0.1 13.3 14 0 0 14 14 14 0 DBF zinc finger zf-Sec23_Sec24 PF04810.15 KFM79698.1 - 0.018 15.1 66.5 0.035 14.2 0.1 13.6 11 3 4 15 15 15 0 Sec23/Sec24 zinc finger C1_1 PF00130.22 KFM79698.1 - 0.024 14.5 82.8 2.9 7.8 2.2 13.5 2 2 13 15 15 15 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HNH_5 PF14279.6 KFM79698.1 - 0.047 13.5 75.7 1.8 8.5 1.9 12.7 8 5 1 9 9 9 0 HNH endonuclease GAGA PF09237.11 KFM79698.1 - 0.082 12.7 34.0 1.6 8.6 0.1 9.9 3 3 10 13 13 13 0 GAGA factor NAD_kinase PF01513.21 KFM79698.1 - 0.095 11.9 0.0 13 4.8 0.0 3.3 1 1 1 2 2 2 0 ATP-NAD kinase Nore1-SARAH PF16517.5 KFM79698.1 - 0.099 12.6 0.0 3.8 7.5 0.0 3.6 3 0 0 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain zf-C2H2_9 PF16293.5 KFM79698.1 - 0.26 11.2 69.9 12 5.8 0.1 14.5 1 1 14 15 15 15 0 C2H2 type zinc-finger (1 copy) C5HCH PF17982.1 KFM79698.1 - 0.41 10.8 70.5 3.1 8.0 2.8 13.8 11 3 4 15 15 15 0 NSD Cys-His rich domain TRAF6_Z2 PF18048.1 KFM79698.1 - 0.49 10.5 71.7 0.42 10.8 0.5 13.3 14 1 0 14 14 13 0 TNF receptor-associated factor 6 zinc finger 2 PqqA PF08042.11 KFM79698.1 - 0.49 10.5 10.5 5.7e+02 0.8 0.0 8.6 12 0 0 12 12 11 0 PqqA family zf-Dof PF02701.15 KFM79698.1 - 1.2 9.3 45.4 2.1 8.5 0.6 10.0 3 2 7 10 10 10 0 Dof domain, zinc finger zinc_ribbon_15 PF17032.5 KFM79698.1 - 2.4 9.0 61.9 4.3 8.2 3.3 7.9 1 1 6 9 9 9 0 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM79698.1 - 3.1 8.0 59.7 24 5.1 5.3 6.7 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type Tub PF01167.18 KFM79701.1 - 2e-25 89.9 0.1 3.7e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Tub family RRM_1 PF00076.22 KFM79702.1 - 3.5e-15 55.6 0.0 9.5e-15 54.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 KFM79702.1 - 1.7e-08 34.0 1.2 1.7e-08 34.0 1.2 2.1 2 0 0 2 2 2 1 SAP domain RRM_5 PF13893.6 KFM79702.1 - 0.021 14.4 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) STAC2_u1 PF16664.5 KFM79703.1 - 0.18 12.2 2.2 0.72 10.3 2.2 1.9 1 1 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Cadherin PF00028.17 KFM79704.1 - 1.2e-89 294.8 20.3 3.1e-16 59.6 0.1 7.7 7 1 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 KFM79704.1 - 7.2e-06 25.8 0.1 2.3 8.1 0.0 5.1 4 1 0 4 4 4 2 Cadherin-like Cadherin_4 PF17803.1 KFM79704.1 - 0.18 12.5 0.1 0.18 12.5 0.1 5.9 5 1 1 6 6 6 0 Bacterial cadherin-like domain Cadherin PF00028.17 KFM79705.1 - 5.5e-87 286.4 18.4 3.9e-21 75.3 0.2 8.5 8 0 0 8 8 8 8 Cadherin domain Cadherin_3 PF16184.5 KFM79705.1 - 5.3e-12 45.7 11.6 0.43 10.6 0.1 6.5 6 0 0 6 6 6 4 Cadherin-like Cadherin_2 PF08266.12 KFM79705.1 - 0.013 15.3 0.0 7.3 6.5 0.0 4.2 4 0 0 4 4 4 0 Cadherin-like Flavi_glycop_C PF02832.16 KFM79705.1 - 0.6 10.3 3.4 2.7 8.2 0.4 3.6 4 0 0 4 4 4 0 Flavivirus glycoprotein, immunoglobulin-like domain CHB_HEX_C_1 PF13290.6 KFM79705.1 - 0.68 10.0 6.5 0.32 11.0 0.4 3.7 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain MG4 PF17789.1 KFM79705.1 - 0.8 9.9 3.5 1.9 8.7 0.1 3.3 3 0 0 3 3 3 0 Macroglobulin domain MG4 Homeodomain PF00046.29 KFM79706.1 - 1.1e-19 70.0 3.1 1.5e-19 69.6 3.1 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM79706.1 - 5.2e-06 26.3 0.2 9.4e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFM79706.1 - 0.0018 17.7 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Cytochrom_B_N_2 PF13631.6 KFM79707.1 - 0.0073 16.3 0.3 0.0082 16.2 0.3 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB RSN1_TM PF13967.6 KFM79707.1 - 0.012 15.3 0.5 0.017 14.9 0.5 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport VSP PF03302.13 KFM79707.1 - 0.015 14.2 0.1 0.017 14.0 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein MHC2-interact PF09307.10 KFM79707.1 - 0.053 13.5 1.1 0.079 13.0 0.5 1.6 1 1 1 2 2 2 0 CLIP, MHC2 interacting Epiglycanin_C PF14654.6 KFM79707.1 - 0.057 13.5 0.5 0.057 13.5 0.5 2.1 1 1 1 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Adeno_E3_CR2 PF02439.15 KFM79707.1 - 0.44 10.3 4.5 0.15 11.9 1.1 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF2721 PF11026.8 KFM79707.1 - 0.98 9.3 4.0 0.87 9.5 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2273 PF10031.9 KFM79707.1 - 2.7 8.1 9.5 0.54 10.3 2.0 2.2 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) Virul_fac_BrkB PF03631.15 KFM79708.1 - 0.00073 19.2 0.3 0.00086 19.0 0.3 1.1 1 0 0 1 1 1 1 Virulence factor BrkB DUF202 PF02656.15 KFM79708.1 - 0.013 15.9 0.4 0.019 15.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Glucos_trans_II PF14264.6 KFM79708.1 - 0.023 14.1 0.1 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII DHHC PF01529.20 KFM79708.1 - 0.025 14.7 0.4 0.029 14.5 0.4 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase RSN1_TM PF13967.6 KFM79708.1 - 0.037 13.8 0.3 0.051 13.3 0.3 1.3 1 1 0 1 1 1 0 Late exocytosis, associated with Golgi transport Cation_ATPase_C PF00689.21 KFM79708.1 - 0.04 13.6 0.2 0.044 13.5 0.2 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Col_cuticle_N PF01484.17 KFM79708.1 - 0.04 14.0 0.5 0.04 14.0 0.5 1.8 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain m04gp34like PF12216.8 KFM79708.1 - 0.041 13.5 0.1 0.045 13.3 0.1 1.1 1 0 0 1 1 1 0 Immune evasion protein PET117 PF15786.5 KFM79708.1 - 0.069 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial VSP PF03302.13 KFM79708.1 - 0.12 11.2 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Giardia variant-specific surface protein Glycophorin_A PF01102.18 KFM79708.1 - 0.12 12.6 0.1 0.16 12.2 0.0 1.3 1 1 0 1 1 1 0 Glycophorin A CYYR1 PF10873.8 KFM79708.1 - 0.14 12.6 0.6 0.19 12.2 0.3 1.3 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Syndecan PF01034.20 KFM79708.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Syndecan domain DUF5305 PF17231.2 KFM79708.1 - 0.18 11.2 0.0 0.21 11.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Orf78 PF06024.12 KFM79708.1 - 0.31 11.4 0.0 0.31 11.4 0.0 1.8 1 1 1 2 2 2 0 Orf78 (ac78) Methyltransf_31 PF13847.6 KFM79710.1 - 5.2e-12 45.8 0.0 6.9e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM79710.1 - 5.8e-12 46.2 0.0 9.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM79710.1 - 1.9e-10 40.8 0.0 4.9e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM79710.1 - 3.3e-10 40.6 0.0 8.1e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM79710.1 - 1.1e-09 38.8 0.0 2.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM79710.1 - 1.5e-05 24.4 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 KFM79710.1 - 0.016 14.7 0.0 0.074 12.5 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB MTS PF05175.14 KFM79710.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain YjgF_endoribonc PF14588.6 KFM79710.1 - 0.12 12.5 0.0 4.6 7.4 0.0 2.2 2 0 0 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease DUF2244 PF10003.9 KFM79711.1 - 1.2 8.8 2.4 2.4 7.8 2.4 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Cadherin PF00028.17 KFM79712.1 - 1.4e-18 67.1 1.3 1e-10 41.9 0.4 2.8 3 0 0 3 3 3 2 Cadherin domain Cadherin_4 PF17803.1 KFM79712.1 - 0.015 15.9 0.1 0.048 14.3 0.1 1.9 1 0 0 1 1 1 0 Bacterial cadherin-like domain DUF3421 PF11901.8 KFM79713.1 - 4.4e-45 152.4 7.2 1.7e-40 137.6 2.3 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) B2 PF11473.8 KFM79714.1 - 0.0024 17.6 0.1 0.0039 16.9 0.1 1.5 1 1 0 1 1 1 1 RNA binding protein B2 zf-BED PF02892.15 KFM79714.1 - 0.011 15.8 0.8 0.034 14.2 0.1 2.0 2 0 0 2 2 2 0 BED zinc finger HECW_N PF16562.5 KFM79717.1 - 1.8e-39 134.2 0.0 3.5e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HECW1_helix PF18436.1 KFM79717.1 - 1.7e-38 130.6 2.4 3e-35 120.1 0.5 2.5 2 0 0 2 2 2 2 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 KFM79717.1 - 9.5e-15 54.4 0.0 1.2e-07 31.7 0.1 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.30 KFM79717.1 - 5.2e-09 36.3 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain SKICH PF17751.1 KFM79717.1 - 0.01 16.4 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 SKICH domain DUF2505 PF10698.9 KFM79717.1 - 0.068 13.3 0.0 0.28 11.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) PDZ_6 PF17820.1 KFM79719.1 - 2e-06 27.6 0.1 3.5e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM79719.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain CDCA PF18484.1 KFM79719.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat Roc PF08477.13 KFM79720.1 - 7.9e-12 45.4 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM79720.1 - 1.4e-09 37.8 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFM79720.1 - 8.3e-07 28.6 0.0 9.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFM79720.1 - 0.0061 15.8 0.2 0.49 9.5 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.6 KFM79720.1 - 0.038 14.5 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFM79720.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KFM79720.1 - 0.084 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM79720.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit CUE PF02845.16 KFM79721.1 - 1.7e-13 50.0 0.1 2.4e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 CUE domain TMEM52 PF14979.6 KFM79721.1 - 0.0085 16.0 0.4 0.012 15.6 0.4 1.3 1 0 0 1 1 1 1 Transmembrane 52 DMA PF03474.14 KFM79721.1 - 0.0098 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 DMRTA motif DEAD PF00270.29 KFM79722.1 - 0.0085 15.9 0.0 0.0085 15.9 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase GOLGA2L5 PF15070.6 KFM79722.1 - 0.036 12.7 0.0 0.041 12.6 0.0 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DEAD PF00270.29 KFM79723.1 - 0.062 13.1 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM79724.1 - 2.8e-07 30.8 0.0 4.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sod_Cu PF00080.20 KFM79725.1 - 0.13 12.4 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) COG7 PF10191.9 KFM79726.1 - 4.5e-46 157.5 0.1 4.8e-46 157.4 0.1 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) GRAS PF03514.14 KFM79726.1 - 0.014 14.3 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family COG7 PF10191.9 KFM79727.1 - 9.4e-60 202.7 6.3 1.1e-59 202.5 6.3 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) Ribonuc_2-5A PF06479.12 KFM79727.1 - 0.06 13.5 0.4 3.2 8.0 0.2 2.4 2 0 0 2 2 2 0 Ribonuclease 2-5A COG7 PF10191.9 KFM79728.1 - 4.1e-52 177.5 7.2 4.6e-52 177.3 7.2 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) COG5 PF10392.9 KFM79728.1 - 2.6e-05 24.4 1.3 3.3e-05 24.1 1.3 1.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF1664 PF07889.12 KFM79728.1 - 0.018 15.1 6.9 0.029 14.4 5.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CDC13_N PF16853.5 KFM79728.1 - 0.018 14.6 1.0 0.021 14.4 1.0 1.1 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus DASH_Spc19 PF08287.11 KFM79728.1 - 0.019 14.9 1.7 0.025 14.5 1.7 1.2 1 0 0 1 1 1 0 Spc19 Apolipoprotein PF01442.18 KFM79728.1 - 0.02 14.8 3.3 0.032 14.1 3.3 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fez1 PF06818.15 KFM79728.1 - 0.036 14.5 3.5 0.044 14.2 3.5 1.1 1 0 0 1 1 1 0 Fez1 SlyX PF04102.12 KFM79728.1 - 0.057 14.0 2.5 0.081 13.5 1.7 1.7 1 1 1 2 2 2 0 SlyX DUF948 PF06103.11 KFM79728.1 - 0.067 13.5 3.9 0.35 11.2 3.9 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2742 PF10888.8 KFM79728.1 - 0.094 13.0 0.8 0.22 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) Laminin_II PF06009.12 KFM79728.1 - 0.14 12.2 5.8 0.35 10.9 5.8 1.8 1 1 0 1 1 1 0 Laminin Domain II TMPIT PF07851.13 KFM79728.1 - 0.16 11.2 3.4 0.19 10.9 3.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Phage_GPO PF05929.11 KFM79728.1 - 0.22 11.1 4.1 0.28 10.8 4.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GCN5L1 PF06320.13 KFM79728.1 - 0.24 11.5 8.0 0.58 10.3 3.4 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) LPP PF04728.13 KFM79728.1 - 1.1 9.7 7.8 15 6.1 3.1 3.6 1 1 2 3 3 3 0 Lipoprotein leucine-zipper Acetyltransf_1 PF00583.25 KFM79729.1 - 7.5e-15 55.2 0.0 9.2e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM79729.1 - 6.4e-10 39.1 0.1 7.8e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM79729.1 - 4.7e-09 36.5 0.0 6.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM79729.1 - 3.4e-07 30.1 0.0 5.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KFM79729.1 - 0.0064 16.0 1.5 0.0071 15.8 0.2 1.6 1 1 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 KFM79729.1 - 0.011 15.8 0.1 0.021 14.9 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFM79729.1 - 0.023 15.3 0.0 0.036 14.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KFM79729.1 - 0.028 14.4 0.1 0.048 13.7 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PanZ PF12568.8 KFM79729.1 - 0.078 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_17 PF17668.1 KFM79729.1 - 0.14 12.9 0.1 0.92 10.3 0.0 1.9 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain HTH_48 PF17906.1 KFM79730.1 - 3.3e-06 27.1 0.1 5.7e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 KFM79730.1 - 0.00051 20.6 0.0 0.00072 20.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM79730.1 - 0.0012 19.0 0.0 0.013 15.8 0.0 2.0 2 0 0 2 2 2 1 Transposase HTH_24 PF13412.6 KFM79730.1 - 0.0053 16.3 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KFM79730.1 - 0.0074 16.1 0.0 0.1 12.4 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_15 PF12324.8 KFM79730.1 - 0.0099 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of alkylmercury lyase Sigma70_r4 PF04545.16 KFM79730.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF977 PF06163.11 KFM79730.1 - 0.099 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_9 PF08221.11 KFM79730.1 - 0.12 12.5 0.1 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_37 PF13744.6 KFM79730.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Transposase_1 PF01359.18 KFM79731.1 - 2.8e-17 62.3 0.0 4.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM79731.1 - 1.7e-07 31.1 0.1 2e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease SET PF00856.28 KFM79732.1 - 3.4e-11 43.8 0.2 3.4e-11 43.8 0.2 3.1 3 0 0 3 3 3 1 SET domain Tim29 PF10171.9 KFM79734.1 - 4.7e-19 68.5 0.0 5.4e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Translocase of the Inner Mitochondrial membrane 29 TGFb_propeptide PF00688.18 KFM79735.1 - 0.005 16.6 0.6 0.0064 16.3 0.6 1.2 1 0 0 1 1 1 1 TGF-beta propeptide Sigma70_r4 PF04545.16 KFM79735.1 - 0.081 12.5 2.4 0.35 10.4 0.2 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 Arg_decarbox_C PF17944.1 KFM79735.1 - 0.23 12.1 1.6 6.1 7.5 0.1 2.5 2 1 1 3 3 3 0 Arginine decarboxylase C-terminal helical extension Ldl_recept_a PF00057.18 KFM79736.1 - 3.3e-09 36.8 8.6 8.7e-09 35.5 8.6 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFM79736.1 - 0.00071 19.9 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 CUB domain Arf PF00025.21 KFM79737.1 - 1.7e-79 265.3 0.1 2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFM79737.1 - 1.4e-14 53.9 0.0 1.7e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFM79737.1 - 5.9e-14 52.3 0.0 8.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM79737.1 - 1.3e-12 47.6 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFM79737.1 - 1.7e-11 43.9 1.3 1.3e-07 31.1 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFM79737.1 - 3.9e-10 39.5 0.0 4.7e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM79737.1 - 2.3e-05 24.4 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFM79737.1 - 0.006 15.9 0.4 0.024 14.0 0.1 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase PUF PF00806.19 KFM79738.1 - 8.3e-38 126.0 2.9 7.1e-09 34.9 0.3 4.5 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat DUF19 PF01579.18 KFM79739.1 - 0.0085 15.9 9.8 0.029 14.2 9.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF19) RGM_N PF06535.12 KFM79739.1 - 0.038 14.2 4.5 0.094 12.9 4.6 1.7 1 1 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus DUF3586 PF12131.8 KFM79740.1 - 1.3 9.3 4.7 0.32 11.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) DUF19 PF01579.18 KFM79742.1 - 0.056 13.2 17.6 0.15 11.8 17.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF19) DUF1024 PF06260.12 KFM79742.1 - 0.09 13.1 0.1 24 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) DUF5325 PF17259.2 KFM79742.1 - 7.5 6.5 9.0 1.4 8.8 0.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Integrase_H2C2 PF17921.1 KFM79743.1 - 0.00012 22.2 0.1 0.00014 21.9 0.1 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain VHL_C PF17211.3 KFM79744.1 - 0.074 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 VHL box domain AAA_21 PF13304.6 KFM79745.1 - 3.9e-08 33.5 0.0 6.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KFM79745.1 - 1.9e-06 28.4 0.1 3.4e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter DUF2492 PF10678.9 KFM79745.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) DUF378 PF04070.12 KFM79746.1 - 0.0037 17.1 6.7 0.011 15.7 6.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF378) ABC2_membrane_3 PF12698.7 KFM79746.1 - 0.12 11.5 24.0 0.14 11.3 24.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein L_HMGIC_fpl PF10242.9 KFM79746.1 - 0.16 12.1 10.6 0.046 13.9 3.3 2.1 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein RRM_1 PF00076.22 KFM79749.1 - 1.4e-36 124.2 0.1 4e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFM79749.1 - 0.0011 18.9 0.6 0.19 11.8 0.0 3.1 3 2 0 3 3 3 2 RNA binding domain Na_Ca_ex PF01699.24 KFM79750.1 - 1.1e-42 145.5 48.2 3.6e-22 79.0 16.5 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Pilin_N PF07790.11 KFM79750.1 - 0.019 15.9 3.4 0.045 14.7 1.5 2.5 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal UCH PF00443.29 KFM79751.1 - 1.3e-16 60.9 0.1 2.3e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFM79751.1 - 3.7e-14 52.8 0.8 7e-14 51.9 0.8 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFM79751.1 - 0.00013 21.7 0.3 0.00013 21.7 0.3 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KFM79751.1 - 0.025 14.3 0.7 0.056 13.2 0.7 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger Ig_3 PF13927.6 KFM79753.1 - 0.052 14.2 0.2 0.086 13.4 0.2 1.5 1 1 0 1 1 1 0 Immunoglobulin domain LIM PF00412.22 KFM79754.1 - 9.1e-08 32.2 10.4 1.3e-07 31.7 10.4 1.3 1 0 0 1 1 1 1 LIM domain fn3 PF00041.21 KFM79755.1 - 4.1e-10 39.9 0.1 7.4e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain I-set PF07679.16 KFM79755.1 - 4.6e-08 33.0 0.0 1.3e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM79755.1 - 0.0024 18.2 0.0 0.0058 16.9 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFM79755.1 - 0.003 18.1 0.0 0.0075 16.8 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM79755.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Immunoglobulin V-set domain PapD_C PF02753.17 KFM79755.1 - 0.079 13.3 0.0 5.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Pili assembly chaperone PapD, C-terminal domain fn3 PF00041.21 KFM79756.1 - 1.1e-07 32.0 0.1 2.3e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain RCR PF12273.8 KFM79756.1 - 0.0011 19.7 1.2 0.0022 18.6 1.2 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.6 KFM79756.1 - 0.015 15.6 0.1 0.02 15.1 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRRC37AB_C PF14914.6 KFM79756.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain BTB PF00651.31 KFM79759.1 - 1.1e-24 86.8 0.0 5.9e-24 84.4 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM79759.1 - 6.6e-08 32.6 1.2 2.5e-07 30.7 0.5 2.2 1 1 1 2 2 2 1 BTB And C-terminal Kelch sCache_3_2 PF17203.4 KFM79759.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Single cache domain 3 TPR_1 PF00515.28 KFM79761.1 - 1.6e-09 37.2 0.0 1.7e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM79761.1 - 5.7e-09 35.4 0.0 6.2e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM79761.1 - 7.1e-09 35.2 0.1 0.00066 19.3 0.0 2.0 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 KFM79761.1 - 3.7e-06 26.7 0.0 3.9e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM79761.1 - 2e-05 24.8 0.0 2.2e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM79761.1 - 2.9e-05 24.6 0.0 2.9e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM79761.1 - 3.2e-05 24.0 0.0 0.00096 19.4 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM79761.1 - 0.00019 21.2 0.0 0.00021 21.0 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM79761.1 - 0.00061 19.6 0.0 0.00066 19.5 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM79761.1 - 0.0027 18.4 0.0 0.0029 18.3 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM79761.1 - 0.0031 18.0 0.0 0.0032 17.9 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM79761.1 - 0.014 16.0 0.0 0.015 15.9 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFM79761.1 - 0.041 14.5 0.0 0.045 14.4 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 KFM79762.1 - 6.1e-38 131.1 0.0 7.9e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFM79762.1 - 5.1e-05 23.0 0.3 0.00011 21.9 0.3 1.6 1 0 0 1 1 1 1 FATC domain PI3_PI4_kinase PF00454.27 KFM79763.1 - 1.3e-07 31.7 0.0 1.5e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DLEU7 PF15760.5 KFM79766.1 - 0.064 12.7 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 Leukemia-associated protein 7 FAT PF02259.23 KFM79767.1 - 1.9e-06 27.3 0.0 1.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 FAT domain Lig_chan-Glu_bd PF10613.9 KFM79769.1 - 5.6e-40 136.1 0.0 1.2e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM79769.1 - 1.3e-18 67.3 0.0 2.4e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 KFM79769.1 - 1.7e-15 57.1 0.6 4.7e-15 55.7 0.6 1.7 2 0 0 2 2 2 1 Ligand-gated ion channel ANF_receptor PF01094.28 KFM79769.1 - 2.4e-09 36.8 0.0 3.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region MLVIN_C PF18697.1 KFM79769.1 - 0.019 15.1 0.0 0.077 13.1 0.0 2.0 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain CbiM PF01891.16 KFM79769.1 - 0.036 13.9 0.2 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region bZIP_Maf PF03131.17 KFM79770.1 - 4.6e-22 78.3 13.7 4.6e-22 78.3 13.7 3.0 2 1 2 4 4 4 1 bZIP Maf transcription factor DUF4407 PF14362.6 KFM79770.1 - 0.2 11.0 3.8 0.37 10.1 3.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1635 PF07795.11 KFM79770.1 - 0.3 10.9 10.2 1.6 8.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Peptidase_M16 PF00675.20 KFM79770.1 - 8.1 6.4 7.4 6.5 6.7 1.4 2.2 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) zf-RING_2 PF13639.6 KFM79771.1 - 2.4e-07 31.0 3.8 2.4e-07 31.0 3.8 5.3 3 1 1 4 4 4 1 Ring finger domain IBR PF01485.21 KFM79771.1 - 5.9e-06 26.4 24.2 0.00035 20.7 12.9 4.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KFM79771.1 - 6.1e-06 26.2 5.3 6.1e-06 26.2 5.3 4.2 5 0 0 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFM79771.1 - 2.7e-05 23.9 4.0 2.7e-05 23.9 4.0 5.2 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM79771.1 - 3.3e-05 23.7 3.2 3.3e-05 23.7 3.2 5.4 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM79771.1 - 0.00015 21.7 3.7 0.00015 21.7 3.7 5.4 3 1 1 4 4 4 1 zinc-RING finger domain UNC45-central PF11701.8 KFM79771.1 - 0.01 15.8 0.5 0.019 14.9 0.5 1.4 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central ubiquitin PF00240.23 KFM79772.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF1108 PF06531.11 KFM79773.1 - 0.063 13.6 0.6 0.14 12.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1108) YwhD PF08741.10 KFM79773.1 - 0.088 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 YwhD family Maf1 PF09174.10 KFM79774.1 - 3.4e-65 219.4 0.3 4.3e-65 219.1 0.3 1.1 1 0 0 1 1 1 1 Maf1 regulator CAP_GLY PF01302.25 KFM79775.1 - 6.7e-27 93.3 0.2 5.6e-15 55.1 0.0 2.6 2 0 0 2 2 2 2 CAP-Gly domain UCH PF00443.29 KFM79775.1 - 1.9e-08 34.1 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-HIT PF04438.16 KFM79775.1 - 2.6 8.0 10.7 0.084 12.8 3.2 2.3 2 0 0 2 2 2 0 HIT zinc finger LRR_4 PF12799.7 KFM79776.1 - 0.00026 21.3 0.3 0.00056 20.3 0.3 1.6 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM79776.1 - 0.00077 19.2 0.1 0.0013 18.5 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRRCT PF01463.24 KFM79776.1 - 0.0013 19.1 0.0 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain TPKR_C2 PF16920.5 KFM79776.1 - 0.051 13.7 0.5 0.5 10.5 0.6 2.3 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain FAD_binding_2 PF00890.24 KFM79777.1 - 2.4e-32 112.6 0.3 2.8e-32 112.3 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFM79777.1 - 0.00029 20.2 0.6 0.00036 19.9 0.4 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM79777.1 - 0.0049 16.0 2.3 0.0054 15.9 1.3 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KFM79777.1 - 0.0054 16.0 0.3 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KFM79777.1 - 0.0063 15.8 0.2 0.0098 15.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFM79777.1 - 0.033 13.8 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFM79777.1 - 0.054 12.2 0.1 0.079 11.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Ig_3 PF13927.6 KFM79778.1 - 2.1e-16 60.2 0.0 5.6e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM79778.1 - 1.9e-11 44.1 0.0 6.3e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM79778.1 - 2.3e-11 43.6 0.0 4.9e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFM79778.1 - 1.3e-08 34.9 0.0 5.7e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM79778.1 - 2.9e-06 27.3 0.0 0.0044 17.0 0.0 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain DUF1771 PF08590.10 KFM79780.1 - 3.6e-16 59.3 5.8 7e-16 58.4 5.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KFM79780.1 - 3.6e-11 43.3 0.1 1e-10 41.8 0.0 1.8 2 0 0 2 2 2 1 Smr domain CUE PF02845.16 KFM79781.1 - 0.015 15.0 0.1 0.042 13.6 0.1 1.7 1 0 0 1 1 1 0 CUE domain AAA_16 PF13191.6 KFM79782.1 - 6e-05 23.5 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KFM79782.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM79782.1 - 0.016 15.8 0.2 0.047 14.2 0.0 1.9 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KFM79782.1 - 0.019 14.2 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Pro-NT_NN PF07421.11 KFM79782.1 - 0.039 14.2 0.2 0.07 13.4 0.2 1.4 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor AAA_30 PF13604.6 KFM79782.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoLip_ATPase_N PF16209.5 KFM79783.1 - 2.2e-23 81.7 0.6 4.1e-23 80.8 0.6 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Ribosomal_L50 PF10501.9 KFM79785.1 - 1.4e-08 34.9 0.1 2.2e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S IDH PF03971.14 KFM79785.1 - 0.19 10.2 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase Nnf1 PF03980.14 KFM79786.1 - 6.3e-11 42.6 1.4 1.2e-10 41.8 0.3 1.9 1 1 0 1 1 1 1 Nnf1 DUF489 PF04356.12 KFM79786.1 - 0.016 15.2 2.9 0.39 10.7 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF489) DUF1741 PF08427.10 KFM79786.1 - 0.024 14.3 0.2 0.041 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) DUF334 PF03904.13 KFM79786.1 - 0.034 13.7 2.4 0.064 12.8 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Sigma_1s PF02454.16 KFM79786.1 - 0.062 13.3 1.4 0.2 11.6 0.7 2.0 2 0 0 2 2 2 0 Sigma 1s protein LMBR1 PF04791.16 KFM79786.1 - 0.068 12.1 4.1 0.081 11.8 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Prominin PF05478.11 KFM79786.1 - 0.11 10.4 3.5 0.11 10.4 2.5 1.3 1 1 0 1 1 1 0 Prominin COMMD1_N PF17221.3 KFM79786.1 - 0.24 11.7 3.4 0.31 11.3 1.2 2.2 2 1 0 2 2 2 0 COMMD1 N-terminal domain Cdh1_DBD_1 PF18196.1 KFM79786.1 - 1.2 9.5 6.8 1.3 9.3 5.2 1.9 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 PT PF04886.12 KFM79788.1 - 0.019 14.5 0.3 0.022 14.3 0.3 1.2 1 0 0 1 1 1 0 PT repeat Cadherin PF00028.17 KFM79789.1 - 1.4e-64 214.5 0.0 1.1e-20 73.8 0.0 4.1 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.12 KFM79789.1 - 7.6e-07 28.9 0.2 0.045 13.6 0.1 3.3 3 1 0 3 3 3 2 Cadherin-like Cadherin_3 PF16184.5 KFM79789.1 - 0.00032 20.7 0.1 0.23 11.5 0.0 2.9 3 1 0 3 3 3 2 Cadherin-like Cadherin_pro PF08758.11 KFM79789.1 - 0.00061 19.9 0.0 0.04 14.1 0.0 2.5 2 0 0 2 2 2 1 Cadherin prodomain like 7tm_1 PF00001.21 KFM79790.1 - 5.2e-45 153.8 12.9 6.8e-45 153.4 12.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM79790.1 - 4.8e-17 62.2 16.0 7.1e-17 61.6 16.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM79790.1 - 9.6e-13 48.3 16.9 9.6e-13 48.3 16.9 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KFM79790.1 - 9.8e-05 21.8 23.4 0.0039 16.5 9.0 3.2 1 1 2 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFM79790.1 - 0.0017 18.1 15.1 0.014 15.1 1.1 3.1 2 1 0 2 2 2 2 Olfactory receptor 7tm_1 PF00001.21 KFM79792.1 - 1.3e-28 100.0 7.4 1.5e-28 99.9 7.2 1.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM79792.1 - 1.1e-07 31.8 11.7 1.4e-07 31.4 11.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFM79792.1 - 0.00046 19.6 5.6 0.00061 19.2 5.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFM79793.1 - 0.015 15.0 0.8 0.017 14.9 0.8 1.0 1 0 0 1 1 1 0 Olfactory receptor 7TM_GPCR_Srw PF10324.9 KFM79793.1 - 0.057 12.7 2.3 0.063 12.6 2.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KFM79793.1 - 0.2 10.9 6.0 0.26 10.6 6.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) HTH_Tnp_Tc3_2 PF01498.18 KFM79794.1 - 1.2e-07 31.9 3.2 1.4e-07 31.6 1.1 2.1 1 1 1 2 2 2 1 Transposase HTH_38 PF13936.6 KFM79794.1 - 0.002 17.9 0.0 0.0065 16.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KFM79794.1 - 0.0052 16.8 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_36 PF13730.6 KFM79794.1 - 0.02 14.9 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KFM79794.1 - 0.049 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain SMC_N PF02463.19 KFM79795.1 - 2.8e-05 23.7 32.6 0.00028 20.4 32.6 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain CBM_14 PF01607.24 KFM79799.1 - 3e-11 43.3 6.5 1.1e-10 41.6 6.0 2.2 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Ig_2 PF13895.6 KFM79799.1 - 0.00047 20.4 0.1 0.0014 18.9 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFM79799.1 - 0.0016 19.0 1.7 0.0032 18.0 0.3 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM79799.1 - 0.003 17.7 1.7 0.029 14.5 0.0 3.1 3 1 1 4 4 4 1 Immunoglobulin V-set domain HRM PF02793.22 KFM79799.1 - 0.031 14.6 4.3 0.15 12.4 0.1 2.7 2 0 0 2 2 2 0 Hormone receptor domain ig PF00047.25 KFM79799.1 - 0.085 13.0 3.4 0.081 13.1 0.5 2.6 2 1 0 2 2 1 0 Immunoglobulin domain HMMR_N PF15905.5 KFM79799.1 - 0.19 11.2 15.8 0.28 10.6 15.8 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 KFM79799.1 - 1.2 9.2 3.7 1.3 9.1 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CCDC92 PF14916.6 KFM79799.1 - 1.3 8.8 4.7 2.1 8.1 0.5 2.9 2 1 0 3 3 3 0 Coiled-coil domain of unknown function DASH_Dam1 PF08653.10 KFM79799.1 - 1.5 8.7 4.0 2.9 7.8 0.3 2.9 2 1 0 2 2 2 0 DASH complex subunit Dam1 DUF4618 PF15397.6 KFM79799.1 - 1.6 8.1 12.4 0.56 9.6 7.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF262 PF03235.14 KFM79799.1 - 1.7 8.7 7.9 1.5 9.0 6.6 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF262 SAPIS-gp6 PF16722.5 KFM79799.1 - 2.9 8.3 6.6 1 9.8 0.4 3.1 4 0 0 4 4 4 0 Pathogenicity island protein gp6 in Staphylococcus ABC_tran_CTD PF16326.5 KFM79799.1 - 4.9 7.5 8.6 0.37 11.1 2.2 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain Wbp11 PF09429.10 KFM79799.1 - 6.1 7.3 6.8 9.4 6.7 0.1 3.1 2 1 1 3 3 3 0 WW domain binding protein 11 GARS_A PF01071.19 KFM79800.1 - 8.9e-79 263.8 0.0 1.8e-78 262.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KFM79800.1 - 7.1e-54 182.2 0.0 4.5e-33 114.6 0.0 3.0 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KFM79800.1 - 2.1e-35 121.4 0.0 1.1e-34 119.0 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain Formyl_trans_N PF00551.19 KFM79800.1 - 2.4e-33 115.4 0.1 4.7e-33 114.4 0.1 1.5 1 0 0 1 1 1 1 Formyl transferase GARS_C PF02843.16 KFM79800.1 - 2.2e-29 101.5 0.3 6.2e-29 100.1 0.3 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KFM79800.1 - 2.6e-25 88.9 0.8 3.1e-11 43.8 0.1 3.5 3 0 0 3 3 3 2 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 KFM79800.1 - 0.00014 21.9 0.0 0.00038 20.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KFM79800.1 - 0.022 14.4 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.22 KFM79800.1 - 0.027 14.0 0.1 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain CPSase_L_D2 PF02786.17 KFM79800.1 - 0.089 12.3 0.3 0.41 10.1 0.1 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain VPS13_mid_rpt PF16910.5 KFM79804.1 - 5.9e-21 75.0 0.7 1.5e-20 73.6 0.1 2.0 3 0 0 3 3 3 1 Repeating coiled region of VPS13 Peptidase_C1 PF00112.23 KFM79805.1 - 1.8e-15 57.6 0.1 2e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.23 KFM79806.1 - 1.5e-50 172.3 0.1 1.7e-50 172.1 0.1 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFM79806.1 - 0.00025 20.0 0.3 0.00033 19.6 0.3 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Meiosis_expr PF15163.6 KFM79806.1 - 0.037 14.7 0.1 0.07 13.8 0.1 1.4 1 0 0 1 1 1 0 Meiosis-expressed Peptidase_C1 PF00112.23 KFM79807.1 - 1.6e-89 299.8 3.8 1.9e-89 299.4 3.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM79807.1 - 5.4e-11 42.8 2.3 9.8e-11 41.9 2.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM79807.1 - 3.7e-05 22.7 1.9 0.0086 14.9 0.3 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KFM79808.1 - 5.4e-89 298.0 3.2 6.6e-89 297.7 3.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM79808.1 - 1.3e-10 41.5 0.7 2.4e-10 40.7 0.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM79808.1 - 0.00017 20.5 3.1 0.013 14.3 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KFM79809.1 - 2.7e-89 299.0 6.9 3.5e-89 298.6 6.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM79809.1 - 1.2e-09 38.5 0.5 2.2e-09 37.6 0.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM79809.1 - 2.7e-05 23.2 1.9 0.013 14.3 0.6 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DM4_12 PF07841.13 KFM79811.1 - 2e-07 31.5 0.5 3.7e-07 30.7 0.5 1.4 1 0 0 1 1 1 1 DM4/DM12 family Ion_trans PF00520.31 KFM79812.1 - 0.1 11.8 0.8 0.15 11.3 0.8 1.2 1 0 0 1 1 1 0 Ion transport protein ETRAMP PF09716.10 KFM79814.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Alg6_Alg8 PF03155.15 KFM79817.1 - 7.3e-51 173.6 10.1 8e-51 173.5 10.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Alg6_Alg8 PF03155.15 KFM79818.1 - 9.3e-39 133.7 13.9 1e-38 133.6 13.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Tom6 PF17112.5 KFM79820.1 - 0.0058 16.1 0.3 0.0064 16.0 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal Ocnus PF05005.15 KFM79824.1 - 4.9e-40 136.0 0.2 5.6e-40 135.8 0.2 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) CRAL_TRIO PF00650.20 KFM79825.1 - 7.7e-36 123.2 1.5 1e-35 122.8 1.5 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFM79825.1 - 1.4e-13 51.5 1.6 2e-05 25.1 0.0 2.9 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.6 KFM79825.1 - 7.3e-08 32.7 0.1 1.3e-07 31.9 0.1 1.4 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM79826.1 - 7.7e-09 35.6 0.2 8.5e-09 35.5 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain THAP PF05485.12 KFM79827.1 - 2.9e-18 66.6 1.6 6.1e-18 65.5 1.6 1.5 1 0 0 1 1 1 1 THAP domain Nnf1 PF03980.14 KFM79827.1 - 0.00027 21.3 0.3 0.00039 20.8 0.3 1.3 1 0 0 1 1 1 1 Nnf1 ZapB PF06005.12 KFM79827.1 - 0.0016 18.8 2.8 0.0028 18.1 2.8 1.3 1 0 0 1 1 1 1 Cell division protein ZapB Chibby PF14645.6 KFM79827.1 - 0.0032 17.9 0.2 0.0052 17.2 0.2 1.4 1 0 0 1 1 1 1 Chibby family DivIC PF04977.15 KFM79827.1 - 0.0035 17.1 3.3 0.0061 16.3 3.3 1.4 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.21 KFM79827.1 - 0.014 15.4 3.6 0.027 14.6 3.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KFM79827.1 - 0.098 12.7 4.0 0.18 11.9 4.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.18 KFM79827.1 - 0.15 12.3 4.0 0.27 11.5 4.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Jnk-SapK_ap_N PF09744.9 KFM79828.1 - 1.6e-16 60.9 12.5 1.6e-16 60.9 12.5 3.2 1 1 2 3 3 3 2 JNK_SAPK-associated protein-1 ADIP PF11559.8 KFM79828.1 - 1.4e-05 25.2 41.4 0.0065 16.6 12.0 3.7 1 1 3 4 4 4 3 Afadin- and alpha -actinin-Binding IFP_35_N PF07334.13 KFM79828.1 - 0.0067 16.5 4.5 0.0067 16.5 4.5 4.6 3 2 1 4 4 4 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus APG6_N PF17675.1 KFM79828.1 - 0.0082 16.7 40.3 0.12 12.9 16.0 3.2 2 1 1 3 3 3 2 Apg6 coiled-coil region Filament PF00038.21 KFM79828.1 - 0.05 13.2 35.1 1.2 8.7 8.5 3.0 1 1 1 3 3 3 0 Intermediate filament protein PRKG1_interact PF15898.5 KFM79828.1 - 0.2 12.6 36.2 0.16 12.9 4.7 3.7 2 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain FPP PF05911.11 KFM79828.1 - 0.36 9.0 40.7 0.052 11.7 27.0 2.1 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil GAS PF13851.6 KFM79828.1 - 0.79 9.0 41.5 0.97 8.7 4.7 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 KFM79828.1 - 1.2 8.3 30.5 0.29 10.4 1.8 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) YabA PF06156.13 KFM79828.1 - 1.4 9.6 30.4 3.2 8.4 7.8 3.9 2 1 0 3 3 3 0 Initiation control protein YabA HALZ PF02183.18 KFM79828.1 - 1.6 9.0 20.7 2.2 8.6 1.5 4.7 3 2 0 4 4 4 0 Homeobox associated leucine zipper Fez1 PF06818.15 KFM79828.1 - 1.8 8.9 35.8 9.4 6.6 25.3 3.0 1 1 1 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 KFM79828.1 - 2.5 8.1 44.0 0.44 10.6 14.2 3.3 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KFM79828.1 - 2.6 7.7 42.8 1.6 8.3 5.8 3.2 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF2203 PF09969.9 KFM79828.1 - 2.7 8.7 20.9 5.8 7.7 2.5 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Tup_N PF08581.10 KFM79828.1 - 3 8.2 32.1 0.096 13.0 2.4 4.5 3 1 1 4 4 4 0 Tup N-terminal DivIC PF04977.15 KFM79828.1 - 4.1 7.2 29.4 5.8 6.8 1.9 4.9 4 1 0 4 4 4 0 Septum formation initiator Fib_alpha PF08702.10 KFM79828.1 - 5.3 7.2 34.3 3.9 7.6 4.5 3.5 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family PilJ PF13675.6 KFM79828.1 - 6 6.9 8.5 4.5 7.3 0.5 3.1 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term TSC22 PF01166.18 KFM79828.1 - 6.6 7.1 19.2 3 8.2 0.8 4.7 3 2 1 4 4 4 0 TSC-22/dip/bun family KASH_CCD PF14662.6 KFM79828.1 - 6.9 6.5 44.2 0.75 9.6 24.6 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH TMF_TATA_bd PF12325.8 KFM79828.1 - 7.8 6.7 33.5 3.4 7.9 1.9 3.7 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding WD40 PF00400.32 KFM79829.1 - 3.9e-24 84.5 29.8 4.6e-06 27.3 0.7 7.7 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM79829.1 - 1.5e-11 44.4 0.3 0.94 9.8 0.0 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM79829.1 - 1.9e-09 37.0 0.0 0.0016 17.4 0.0 4.2 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KFM79829.1 - 1.5e-05 24.5 1.6 0.74 9.1 0.0 4.2 1 1 4 5 5 5 3 Neuroblastoma-amplified sequence, N terminal SOCS_box PF07525.16 KFM79829.1 - 0.00046 20.5 0.2 0.00087 19.6 0.2 1.5 1 0 0 1 1 1 1 SOCS box Nup160 PF11715.8 KFM79829.1 - 0.00047 18.9 0.6 1.5 7.4 0.1 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFM79829.1 - 0.02 13.4 0.1 22 3.4 0.0 3.0 2 1 1 3 3 3 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KFM79829.1 - 0.057 12.2 0.0 1.6 7.4 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like Ion_trans_2 PF07885.16 KFM79830.1 - 9e-20 70.4 5.0 1.5e-19 69.7 5.0 1.3 1 0 0 1 1 1 1 Ion channel MFS_Mycoplasma PF07672.13 KFM79830.1 - 0.013 14.8 0.2 0.035 13.4 0.0 1.6 2 0 0 2 2 2 0 Mycoplasma MFS transporter Thymosin PF01290.20 KFM79832.1 - 5.4e-55 182.9 16.9 7e-16 57.7 2.2 4.1 4 0 0 4 4 4 4 Thymosin beta-4 family DUF4522 PF15022.6 KFM79832.1 - 0.00021 21.5 6.6 1.3 9.3 0.1 3.9 1 1 3 4 4 4 3 Protein of unknown function (DUF4522) DNA_pol_A_exo1 PF01612.20 KFM79833.1 - 1.1e-24 87.0 0.3 3.9e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease RNB PF00773.19 KFM79835.1 - 4.5e-96 322.0 0.0 6.1e-96 321.6 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KFM79835.1 - 4.1e-20 71.6 0.0 8.3e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 KFM79835.1 - 1.1e-15 57.6 0.0 1.9e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 KFM79835.1 - 8.8e-10 38.6 0.2 1.1e-06 28.7 0.0 3.5 3 0 0 3 3 3 2 Cold shock domain Rrp44_S1 PF17215.3 KFM79835.1 - 1.1e-07 31.7 0.0 2.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 S1 domain OB_RNB PF08206.11 KFM79835.1 - 0.044 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain PIN_4 PF13638.6 KFM79836.1 - 1.1e-10 41.9 0.1 1.6e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 PIN domain EcpB_C PF18649.1 KFM79836.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 EcpB C-terminal domain Aminotran_1_2 PF00155.21 KFM79837.1 - 2.2e-61 208.0 0.0 1.4e-60 205.4 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFM79837.1 - 0.00032 20.1 0.1 0.00047 19.5 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KFM79837.1 - 0.0024 16.7 0.0 0.0058 15.4 0.0 1.6 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 KFM79837.1 - 0.0029 16.6 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF1107 PF06526.12 KFM79837.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1107) HAT_KAT11 PF08214.11 KFM79838.1 - 2.5e-49 168.5 3.8 8.4e-49 166.7 3.8 1.9 1 1 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 KFM79838.1 - 5.7e-19 68.0 1.1 1.8e-18 66.3 1.1 1.9 1 0 0 1 1 1 1 Bromodomain DUF902 PF06001.13 KFM79838.1 - 3.3e-12 46.7 4.4 1.3e-11 44.8 4.0 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) ZZ PF00569.17 KFM79838.1 - 3.6e-10 39.5 10.3 3.6e-10 39.5 10.3 4.5 5 0 0 5 5 5 1 Zinc finger, ZZ type zf-TAZ PF02135.16 KFM79838.1 - 1.2e-07 32.0 18.0 1.2e-07 32.0 18.0 4.6 4 0 0 4 4 4 1 TAZ zinc finger IIGP PF05049.13 KFM79838.1 - 0.12 11.4 0.1 9.7 5.1 0.0 2.8 2 1 1 3 3 3 0 Interferon-inducible GTPase (IIGP) CBM_14 PF01607.24 KFM79839.1 - 2e-39 133.5 26.0 3.4e-13 49.6 2.9 3.3 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Trypsin PF00089.26 KFM79840.1 - 3.9e-57 193.6 0.7 5.6e-57 193.1 0.7 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFM79840.1 - 3.6e-15 56.3 0.0 7.3e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 CUB domain Trypsin_2 PF13365.6 KFM79840.1 - 2e-09 38.5 0.0 3.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM79840.1 - 5.6e-06 26.7 0.0 4.7e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.18 KFM79840.1 - 0.0005 20.2 10.7 0.0005 20.2 10.7 2.5 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A Trypsin PF00089.26 KFM79841.1 - 1.6e-52 178.5 0.2 2.2e-52 178.1 0.2 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFM79841.1 - 9.5e-18 64.5 0.0 2.3e-17 63.3 0.0 1.6 2 0 0 2 2 2 1 CUB domain Ldl_recept_a PF00057.18 KFM79841.1 - 6.7e-09 35.8 14.0 2.3e-08 34.1 14.0 2.0 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Trypsin_2 PF13365.6 KFM79841.1 - 4.5e-07 30.9 0.0 8.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM79841.1 - 6.9e-06 26.4 0.0 4.2e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 KFM79841.1 - 0.014 15.0 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 CUB_2 PF02408.20 KFM79841.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 CUB-like domain CHCH PF06747.13 KFM79842.1 - 0.00029 20.9 0.7 0.00072 19.6 0.7 1.7 1 1 0 1 1 1 1 CHCH domain CX9C PF16860.5 KFM79842.1 - 0.0024 17.9 1.6 0.0037 17.2 1.6 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Shisa PF13908.6 KFM79846.1 - 3.6e-05 24.1 3.8 3.6e-05 24.1 3.8 2.1 1 1 1 2 2 2 2 Wnt and FGF inhibitory regulator RCR PF12273.8 KFM79846.1 - 0.0015 19.1 2.8 0.003 18.2 2.8 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 KFM79846.1 - 0.0053 17.6 0.0 0.0067 17.3 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KFM79846.1 - 0.29 11.1 4.2 0.55 10.2 4.2 1.4 1 0 0 1 1 1 0 Syndecan domain PRA1 PF03208.19 KFM79847.1 - 9.6e-37 125.8 7.6 1.2e-36 125.5 7.6 1.1 1 0 0 1 1 1 1 PRA1 family protein Cytochrom_B_C PF00032.17 KFM79847.1 - 2.8 8.3 6.9 2.7 8.3 4.1 2.1 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF2304 PF10066.9 KFM79847.1 - 4.7 7.5 12.6 0.36 11.1 1.2 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2304) Sugar_tr PF00083.24 KFM79850.1 - 2.6e-87 293.6 30.4 3.3e-87 293.2 30.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM79850.1 - 8.5e-29 100.6 36.1 3.4e-27 95.3 35.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF5056 PF16479.5 KFM79850.1 - 0.088 13.0 4.0 0.96 9.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) Herpes_US9 PF06072.11 KFM79850.1 - 0.74 9.7 0.0 0.74 9.7 0.0 3.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 CAP_N PF01213.19 KFM79851.1 - 1.6e-53 182.3 0.0 2e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KFM79851.1 - 8e-40 136.0 1.5 1.1e-39 135.6 1.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KFM79851.1 - 9.7e-06 25.3 6.3 1.6e-05 24.6 6.3 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C ATG16 PF08614.11 KFM79852.1 - 6e-32 111.5 27.2 6e-32 111.5 27.2 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 KFM79852.1 - 5.5e-28 96.6 24.3 8.1e-05 23.3 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM79852.1 - 2.6e-08 34.1 1.4 0.46 10.8 0.1 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain HALZ PF02183.18 KFM79852.1 - 0.0019 18.4 1.0 0.0019 18.4 1.0 4.0 4 0 0 4 4 4 1 Homeobox associated leucine zipper HrpB7 PF09486.10 KFM79852.1 - 0.017 15.5 1.2 0.017 15.5 1.2 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Sulfatase_C PF14707.6 KFM79852.1 - 0.6 10.9 2.5 66 4.3 0.0 3.3 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase HMMR_N PF15905.5 KFM79852.1 - 1.1 8.7 35.7 1.9 7.9 35.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 KFM79852.1 - 2.1 7.6 14.4 3.3 7.0 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KFM79852.1 - 4.8 7.6 32.4 0.22 11.9 22.6 2.1 1 1 1 2 2 2 0 Fez1 GAS PF13851.6 KFM79852.1 - 9.9 5.5 40.1 1.5 8.1 3.4 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Dpy-30 PF05186.13 KFM79853.1 - 0.0018 17.9 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 KFM79853.1 - 0.0073 16.0 0.3 0.05 13.3 0.1 2.4 3 0 0 3 3 3 1 Regulatory subunit of type II PKA R-subunit Hemocyanin_M PF00372.19 KFM79856.1 - 9.7e-71 238.1 0.0 1.3e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Hemocyanin_C PF03723.14 KFM79856.1 - 6.6e-38 130.4 0.0 9.6e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_N PF03722.14 KFM79856.1 - 6.4e-15 55.8 0.0 2.2e-14 54.0 0.0 1.9 1 1 0 1 1 1 1 Hemocyanin, all-alpha domain Tyrosinase PF00264.20 KFM79856.1 - 4.3e-08 33.7 0.8 6.1e-08 33.2 0.8 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase LRR_6 PF13516.6 KFM79859.1 - 1.6e-21 74.5 0.0 0.0015 18.4 0.0 5.1 5 0 0 5 5 5 5 Leucine Rich repeat LRR_1 PF00560.33 KFM79859.1 - 8.7e-06 25.6 0.2 8.4 7.4 0.0 4.6 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.7 KFM79859.1 - 1.5e-05 25.3 0.0 0.043 14.2 0.0 3.1 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Colipase-like PF15083.6 KFM79859.1 - 0.32 11.1 6.4 5.8 7.1 6.5 2.7 1 1 0 1 1 1 0 Colipase-like IL13 PF03487.13 KFM79859.1 - 0.54 10.0 3.1 6.6 6.5 0.3 2.7 1 1 3 4 4 4 0 Interleukin-13 LA-virus_coat PF09220.10 KFM79860.1 - 0.19 10.3 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 L-A virus, major coat protein UDG PF03167.19 KFM79864.1 - 1.4e-10 41.4 0.1 1.7e-08 34.6 0.0 2.2 1 1 0 2 2 2 2 Uracil DNA glycosylase superfamily DUF4918 PF16265.5 KFM79864.1 - 2.8e-07 30.3 0.1 1.1e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4918) RE_XcyI PF09571.10 KFM79864.1 - 0.12 11.6 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 XcyI restriction endonuclease Y_phosphatase3 PF13350.6 KFM79866.1 - 0.15 12.0 0.1 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family G_path_suppress PF15991.5 KFM79867.1 - 1.3e-55 189.6 18.4 1.6e-55 189.3 18.4 1.1 1 0 0 1 1 1 1 G-protein pathway suppressor OSTbeta PF15048.6 KFM79867.1 - 0.43 10.7 5.0 0.72 10.0 5.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein V_ATPase_I PF01496.19 KFM79867.1 - 1.2 6.9 5.6 1.7 6.5 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KFM79867.1 - 1.5 8.3 5.6 1.3 8.5 4.4 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit MIF4G_like_2 PF09090.11 KFM79867.1 - 2.9 7.3 8.4 4.4 6.7 8.4 1.2 1 0 0 1 1 1 0 MIF4G like AAA_23 PF13476.6 KFM79867.1 - 9.5 6.7 10.5 17 5.8 10.5 1.3 1 0 0 1 1 1 0 AAA domain FG-GAP PF01839.23 KFM79868.1 - 0.21 11.8 2.7 0.33 11.1 2.7 1.3 1 0 0 1 1 1 0 FG-GAP repeat VCBS PF13517.6 KFM79869.1 - 5.5e-06 26.9 9.2 0.0069 17.0 0.1 3.1 2 2 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFM79869.1 - 0.00015 21.8 9.7 0.2 11.8 0.4 4.4 4 0 0 4 4 4 2 FG-GAP repeat zf-H2C2_2 PF13465.6 KFM79871.1 - 7e-07 29.4 0.5 7e-07 29.4 0.5 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79871.1 - 7.8e-06 26.1 18.9 0.0067 16.8 5.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79871.1 - 7.9e-05 23.2 14.9 0.0064 17.2 2.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM79871.1 - 0.0016 18.2 4.2 0.0016 18.2 4.2 2.9 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf-AN1 PF01428.16 KFM79871.1 - 0.14 12.3 8.7 0.61 10.3 4.7 2.6 2 1 0 2 2 2 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 KFM79871.1 - 0.27 11.4 3.8 1.5 9.0 0.8 2.2 2 0 0 2 2 2 0 Zinc ribbon domain CpXC PF14353.6 KFM79871.1 - 0.62 10.1 4.7 1.6 8.8 0.9 2.0 1 1 1 2 2 2 0 CpXC protein TNFR_c6 PF00020.18 KFM79871.1 - 1.6 9.2 7.7 0.52 10.8 2.4 2.2 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region Glyco_transf_49 PF13896.6 KFM79874.1 - 4.9e-99 331.8 0.0 6.3e-99 331.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan DUF3029 PF11230.8 KFM79874.1 - 0.14 10.5 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) FH2 PF02181.23 KFM79875.1 - 0.0091 15.1 1.5 0.0091 15.1 1.5 1.9 1 1 1 2 2 2 1 Formin Homology 2 Domain PEX11 PF05648.14 KFM79875.1 - 0.081 12.4 0.8 0.09 12.2 0.8 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Drf_FH1 PF06346.12 KFM79877.1 - 2e-20 73.1 223.6 1.1e-16 60.9 119.4 3.4 3 1 1 4 4 4 2 Formin Homology Region 1 FH2 PF02181.23 KFM79877.1 - 0.0016 17.6 3.5 0.0016 17.6 3.5 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain SRPRB PF09439.10 KFM79880.1 - 1.9e-49 167.6 0.2 2.3e-49 167.3 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KFM79880.1 - 2.8e-15 56.2 0.0 4e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM79880.1 - 7.3e-07 29.3 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM79880.1 - 0.0001 21.9 0.0 0.00029 20.4 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFM79880.1 - 0.00064 19.3 0.2 0.1 12.1 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KFM79880.1 - 0.0024 18.1 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFM79880.1 - 0.034 13.5 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFM79880.1 - 0.041 13.7 0.0 0.087 12.6 0.0 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF463 PF04317.12 KFM79880.1 - 0.089 11.7 0.1 0.16 10.8 0.0 1.4 2 0 0 2 2 2 0 YcjX-like family, DUF463 TniB PF05621.11 KFM79880.1 - 0.092 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_14 PF13173.6 KFM79880.1 - 0.1 12.7 0.1 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM79880.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain MWFE PF15879.5 KFM79881.1 - 1.1e-06 28.7 0.0 1.2e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit zf-UBP PF02148.19 KFM79882.1 - 1.1e-20 73.7 7.1 2.3e-20 72.7 7.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF4407 PF14362.6 KFM79882.1 - 0.02 14.2 13.3 0.028 13.8 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAGH_C PF16123.5 KFM79882.1 - 0.032 14.7 5.1 0.033 14.7 2.7 2.2 1 1 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus UPF0242 PF06785.11 KFM79882.1 - 0.035 14.2 22.7 0.057 13.5 22.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KFM79882.1 - 0.13 11.2 23.4 0.21 10.4 23.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C3HC4_3 PF13920.6 KFM79882.1 - 0.15 12.0 2.5 0.27 11.1 2.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_I PF01496.19 KFM79882.1 - 0.28 9.0 15.9 0.33 8.8 15.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 KFM79882.1 - 0.31 10.1 17.5 0.4 9.7 17.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 KFM79882.1 - 0.42 10.7 4.5 0.36 10.9 2.0 1.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 KFM79882.1 - 0.65 9.5 10.3 0.82 9.2 10.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CREPT PF16566.5 KFM79882.1 - 1.1 9.4 18.3 8.7 6.5 7.9 2.4 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ADIP PF11559.8 KFM79882.1 - 1.7 8.7 23.7 2.8 8.0 23.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tweety PF04906.13 KFM79882.1 - 1.7 7.2 7.6 5.5 5.5 3.0 2.2 1 1 0 2 2 2 0 Tweety DUF1664 PF07889.12 KFM79882.1 - 1.8 8.6 10.8 0.43 10.6 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 KFM79882.1 - 5.6 6.2 20.1 2 7.6 13.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 KFM79882.1 - 5.9 6.0 16.4 12 5.1 16.1 1.5 1 1 0 1 1 1 0 TMPIT-like protein Neur_chan_memb PF02932.16 KFM79882.1 - 7.2 6.6 6.2 9.7 6.2 6.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FapA PF03961.13 KFM79882.1 - 7.7 5.0 18.2 8.7 4.8 17.6 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A KELK PF15796.5 KFM79882.1 - 8.4 6.9 26.2 1.3 9.5 17.9 2.9 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF948 PF06103.11 KFM79882.1 - 8.5 6.7 8.6 1.2 9.4 3.5 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BRAP2 PF07576.12 KFM79883.1 - 6.3e-07 29.5 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 Presenilin PF01080.17 KFM79883.1 - 1.6 7.5 4.8 1.8 7.2 4.8 1.4 1 0 0 1 1 1 0 Presenilin Amino_oxidase PF01593.24 KFM79884.1 - 5.1e-126 421.6 0.0 7.8e-126 421.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 KFM79884.1 - 1.9e-17 63.4 0.0 9.2e-17 61.2 0.0 2.2 2 1 1 3 3 1 1 SWIRM domain NAD_binding_8 PF13450.6 KFM79884.1 - 5.5e-15 55.3 0.7 1.3e-14 54.1 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM79884.1 - 1.8e-07 31.1 0.9 4.1e-07 29.9 0.4 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM79884.1 - 1.3e-05 24.5 0.6 2.4e-05 23.6 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFM79884.1 - 1.6e-05 24.3 0.1 4.2e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFM79884.1 - 2.7e-05 23.6 0.5 2.7e-05 23.6 0.5 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KFM79884.1 - 0.00016 22.1 0.4 0.00016 22.1 0.4 2.5 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM79884.1 - 0.0002 20.2 0.8 0.0002 20.2 0.8 2.8 2 1 2 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.19 KFM79884.1 - 0.0003 20.1 0.6 0.00061 19.1 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFM79884.1 - 0.00032 20.0 0.1 0.00069 18.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KFM79884.1 - 0.00053 19.4 2.5 0.00053 19.4 2.5 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFM79884.1 - 0.00081 18.7 0.3 0.00081 18.7 0.3 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM79884.1 - 0.0055 15.8 6.9 0.0055 15.8 0.8 2.3 1 1 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFM79884.1 - 0.0086 15.2 0.2 0.014 14.4 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KFM79884.1 - 0.043 13.2 0.2 0.099 12.0 0.2 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFM79884.1 - 0.054 13.1 0.3 0.11 12.0 0.3 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF489 PF04356.12 KFM79884.1 - 0.1 12.6 2.8 0.2 11.6 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF489) TrkA_N PF02254.18 KFM79884.1 - 0.14 12.5 0.2 0.28 11.5 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF4681 PF15732.5 KFM79884.1 - 0.15 12.3 5.2 0.37 11.1 5.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) XdhC_C PF13478.6 KFM79884.1 - 0.15 12.6 0.1 0.33 11.5 0.1 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain AAA_23 PF13476.6 KFM79884.1 - 0.6 10.6 12.4 0.15 12.6 5.5 2.3 2 0 0 2 2 2 0 AAA domain TolA_bind_tri PF16331.5 KFM79884.1 - 2.9 8.0 11.7 0.96 9.6 7.4 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF4446 PF14584.6 KFM79884.1 - 7.7 6.5 7.3 3.6 7.6 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF1736 PF08409.11 KFM79886.1 - 8.5e-21 73.7 0.4 1.4e-20 73.1 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) DUF4227 PF14004.6 KFM79886.1 - 0.02 14.9 0.0 0.063 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) TPR_8 PF13181.6 KFM79887.1 - 5.9e-37 122.8 13.3 0.00017 21.5 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 KFM79887.1 - 1.2e-36 123.1 24.1 8.7e-05 22.2 0.2 9.9 9 2 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 KFM79887.1 - 5e-35 116.8 18.7 0.00023 21.0 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 KFM79887.1 - 7.6e-26 89.5 18.2 6.9e-07 28.9 0.0 8.6 5 3 4 9 9 9 7 TPR repeat TPR_17 PF13431.6 KFM79887.1 - 9.5e-26 88.3 17.9 0.012 15.9 0.0 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.6 KFM79887.1 - 1.5e-24 86.1 25.6 8.4e-05 22.8 0.1 7.7 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_19 PF14559.6 KFM79887.1 - 2.4e-23 82.4 19.4 4.1e-06 27.2 0.8 5.6 4 1 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 KFM79887.1 - 2.1e-22 79.5 11.1 8.3e-06 26.4 0.5 6.2 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFM79887.1 - 3.1e-17 61.8 14.8 0.093 13.6 0.1 8.5 5 4 3 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFM79887.1 - 1.3e-16 59.3 14.0 0.077 13.1 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFM79887.1 - 5.3e-12 45.6 14.0 0.22 12.2 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM79887.1 - 5.3e-11 42.6 10.6 0.0099 16.1 0.2 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFM79887.1 - 2.6e-10 39.8 23.2 0.37 10.7 0.2 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFM79887.1 - 5.2e-10 39.3 8.9 0.00092 19.3 0.3 5.5 3 1 3 6 6 6 3 Tetratricopeptide repeat Coatomer_E PF04733.14 KFM79887.1 - 3.6e-05 23.3 4.0 0.00033 20.2 0.5 3.4 4 1 0 4 4 4 1 Coatomer epsilon subunit TPR_15 PF13429.6 KFM79887.1 - 5.9e-05 22.4 4.2 0.028 13.6 0.2 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 KFM79887.1 - 0.00012 21.1 5.8 0.22 10.4 3.0 3.2 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 DUF4810 PF16068.5 KFM79887.1 - 0.0014 19.1 0.4 2.6 8.7 0.0 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4810) SNAP PF14938.6 KFM79887.1 - 0.0023 17.4 0.1 0.29 10.5 0.0 3.6 4 0 0 4 4 4 1 Soluble NSF attachment protein, SNAP PPR PF01535.20 KFM79887.1 - 0.0029 17.7 7.6 30 5.2 0.0 6.0 7 0 0 7 7 6 0 PPR repeat TPR_4 PF07721.14 KFM79887.1 - 0.0029 18.1 6.8 14 6.7 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM79887.1 - 0.0044 16.4 8.2 0.95 8.8 0.1 4.6 3 1 1 5 5 5 1 MalT-like TPR region TPR_20 PF14561.6 KFM79887.1 - 0.015 15.6 8.1 7.2 7.0 0.3 4.8 4 1 2 6 6 6 0 Tetratricopeptide repeat HemY_N PF07219.13 KFM79887.1 - 0.066 13.4 0.3 0.54 10.5 0.1 2.5 2 0 0 2 2 2 0 HemY protein N-terminus MIT PF04212.18 KFM79887.1 - 0.53 10.4 11.0 0.83 9.8 0.4 4.3 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 KFM79887.1 - 0.55 10.6 4.8 9.4 6.7 0.4 3.7 3 2 0 3 3 3 0 Bacterial transcriptional activator domain TPR_21 PF09976.9 KFM79887.1 - 1.5 8.5 4.8 40 3.8 0.8 4.1 2 1 0 3 3 3 0 Tetratricopeptide repeat-like domain CDI PF02234.19 KFM79888.1 - 5.2e-18 65.0 0.4 5.2e-18 65.0 0.4 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor DSPc PF00782.20 KFM79889.1 - 2.7e-42 143.7 0.0 5.7e-42 142.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM79889.1 - 0.00021 20.9 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFM79889.1 - 0.031 14.6 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain Rhodanese PF00581.20 KFM79889.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain APOBEC_N PF08210.11 KFM79892.1 - 0.088 12.7 0.8 0.11 12.4 0.8 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain GcnA_N PF18229.1 KFM79892.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 N-acetyl-beta-D-glucosaminidase N-terminal domain zf_C2H2_6 PF18450.1 KFM79894.1 - 0.046 13.4 0.5 0.13 12.0 0.5 1.8 1 0 0 1 1 1 0 Zinc Finger domain DUF1397 PF07165.11 KFM79895.1 - 0.0098 15.3 4.2 0.0098 15.3 4.2 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1397) CPG4 PF15481.6 KFM79895.1 - 6.7 7.4 9.9 0.92 10.2 1.6 2.4 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 CAF1 PF04857.20 KFM79896.1 - 5.8e-24 84.9 0.8 1.3e-11 44.2 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease RNase_H_2 PF13482.6 KFM79896.1 - 0.072 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RNase_H superfamily EGF PF00008.27 KFM79899.1 - 1.3e-216 700.0 597.0 1.4e-08 34.8 6.5 38.2 39 0 0 39 39 36 36 EGF-like domain hEGF PF12661.7 KFM79899.1 - 2.4e-141 456.2 491.3 4e-06 27.3 5.4 38.8 37 2 0 37 37 36 35 Human growth factor-like EGF EGF_CA PF07645.15 KFM79899.1 - 3.3e-66 219.2 582.9 9.2e-11 41.8 5.1 38.5 24 10 14 38 38 34 26 Calcium-binding EGF domain Ank_2 PF12796.7 KFM79899.1 - 6e-33 113.3 18.4 8.8e-14 51.9 2.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 KFM79899.1 - 1.5e-25 88.5 9.9 3.9e-05 23.9 0.2 7.1 6 0 0 6 6 6 6 Ankyrin repeat Notch PF00066.17 KFM79899.1 - 6.8e-23 80.8 50.5 2.5e-10 40.6 10.3 16.8 18 3 0 18 18 3 3 LNR domain NOD PF06816.13 KFM79899.1 - 9.9e-22 76.3 0.0 1.6e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 NOTCH protein Ank_5 PF13857.6 KFM79899.1 - 2.1e-21 75.7 13.8 6.6e-09 35.9 0.3 6.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM79899.1 - 1.3e-19 70.2 1.3 3.7e-06 27.4 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) DUF3454 PF11936.8 KFM79899.1 - 1.7e-19 70.0 20.0 1.7e-19 70.0 20.0 3.2 3 0 0 3 3 2 1 Domain of unknown function (DUF3454) NODP PF07684.12 KFM79899.1 - 4.4e-18 65.2 0.0 3.9e-17 62.2 0.0 2.9 1 0 0 1 1 1 1 NOTCH protein Ank_3 PF13606.6 KFM79899.1 - 6.7e-18 62.9 6.8 0.0025 18.1 0.0 6.8 7 0 0 7 7 6 3 Ankyrin repeat EGF_2 PF07974.13 KFM79899.1 - 4.1e-15 55.8 650.0 0.0032 17.8 10.3 37.7 38 0 0 38 38 35 26 EGF-like domain EGF_3 PF12947.7 KFM79899.1 - 0.00012 22.2 16.7 0.00073 19.7 2.2 38.5 31 7 7 38 38 35 19 EGF domain cEGF PF12662.7 KFM79899.1 - 0.0023 17.8 4.8 0.0023 17.8 4.8 36.0 35 0 0 35 35 31 12 Complement Clr-like EGF-like Ntox22 PF15527.6 KFM79899.1 - 0.004 17.2 0.2 0.0093 16.0 0.2 1.6 1 0 0 1 1 1 1 Bacterial toxin 22 DUF5316 PF17247.2 KFM79899.1 - 0.27 11.3 0.7 0.56 10.3 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5316) FAM60A PF15396.6 KFM79901.1 - 8.9e-15 55.3 0.1 1e-14 55.1 0.1 1.1 1 0 0 1 1 1 1 Protein Family FAM60A Ion_trans PF00520.31 KFM79904.1 - 1.2e-35 122.9 4.5 1.7e-35 122.4 4.5 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFM79904.1 - 1.6e-12 47.3 0.0 4.3e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFM79904.1 - 1.8e-11 43.9 4.6 1.8e-11 43.9 4.6 2.3 2 1 0 2 2 2 1 Ion channel IRK PF01007.20 KFM79904.1 - 0.035 13.9 0.2 0.086 12.6 0.2 1.6 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain BRI3BP PF14965.6 KFM79904.1 - 0.085 12.4 1.2 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Negative regulator of p53/TP53 NPV_P10 PF05531.12 KFM79904.1 - 0.19 12.2 1.8 0.21 12.1 0.3 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein EB1 PF03271.17 KFM79906.1 - 1.3e-17 63.8 4.6 1.9e-17 63.2 3.7 1.8 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KFM79906.1 - 3.7e-14 52.8 0.2 7.7e-14 51.8 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM79906.1 - 0.0053 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain adh_short PF00106.25 KFM79907.1 - 3e-28 98.6 0.0 8.7e-27 93.8 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM79907.1 - 9.7e-19 67.8 0.0 1.7e-17 63.8 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM79907.1 - 4e-09 36.7 0.0 1.2e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFM79907.1 - 3.3e-05 23.5 0.0 6.7e-05 22.5 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KFM79907.1 - 0.07 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KFM79907.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Kelch_1 PF01344.25 KFM79907.1 - 0.81 9.3 3.8 5.4 6.7 0.1 2.8 3 0 0 3 3 3 0 Kelch motif NIPSNAP PF07978.13 KFM79908.1 - 1.1e-30 105.9 0.2 1.3e-30 105.7 0.2 1.0 1 0 0 1 1 1 1 NIPSNAP Gemini_AL1 PF00799.20 KFM79908.1 - 0.13 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain SRI PF08236.11 KFM79909.1 - 1.1e-21 76.7 5.4 2.9e-21 75.4 5.4 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 KFM79909.1 - 7.3e-10 38.8 3.1 1.5e-09 37.8 3.1 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 KFM79909.1 - 0.087 12.9 0.2 19 5.4 0.0 3.3 3 0 0 3 3 3 0 TFIIS helical bundle-like domain DUF4371 PF14291.6 KFM79912.1 - 0.0064 16.2 0.0 0.0065 16.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Ig_3 PF13927.6 KFM79913.1 - 8.4e-41 138.5 0.0 2.8e-13 50.2 0.1 3.9 3 1 1 4 4 4 3 Immunoglobulin domain I-set PF07679.16 KFM79913.1 - 6e-36 122.4 0.0 4.7e-12 45.8 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFM79913.1 - 6.3e-28 96.8 0.0 1.2e-09 38.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM79913.1 - 8.1e-24 83.8 0.0 1.6e-08 34.7 0.0 3.7 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM79913.1 - 2.2e-19 69.6 0.8 1.3e-05 25.3 0.0 5.3 3 3 1 4 4 4 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM79913.1 - 3.7e-07 29.6 0.0 0.03 13.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM79913.1 - 0.0012 18.8 0.1 0.068 13.3 0.1 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 KFM79913.1 - 0.0031 17.7 0.0 0.014 15.6 0.0 2.1 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Herpes_gE PF02480.16 KFM79913.1 - 0.012 14.4 0.0 0.12 11.1 0.0 2.2 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.11 KFM79913.1 - 0.021 14.8 0.0 1.8 8.6 0.0 3.0 3 1 0 3 3 3 0 CD47 immunoglobulin-like domain KASH_CCD PF14662.6 KFM79914.1 - 0.0012 18.7 24.8 0.0012 18.7 24.8 9.4 6 2 3 9 9 9 2 Coiled-coil region of CCDC155 or KASH C5HCH PF17982.1 KFM79915.1 - 5.8e-09 36.0 31.1 0.00043 20.4 12.0 4.4 3 2 1 4 4 4 2 NSD Cys-His rich domain zf-HC5HC2H PF13771.6 KFM79915.1 - 0.00089 19.5 3.8 0.00089 19.5 3.8 4.8 4 1 0 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFM79915.1 - 0.52 10.5 42.5 0.033 14.3 7.3 4.2 2 2 2 4 4 4 0 PHD-zinc-finger like domain PBP PF01161.20 KFM79916.1 - 2.7e-12 47.2 0.3 3e-12 47.0 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-met PF12874.7 KFM79917.1 - 2.1e-29 101.0 27.0 5.5e-06 26.6 0.8 6.4 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM79917.1 - 3.6e-22 78.1 24.5 7.4e-06 26.1 1.0 6.7 6 1 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM79917.1 - 2.5e-18 66.2 36.6 0.00092 19.5 2.7 6.1 1 1 4 6 6 6 6 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM79917.1 - 3e-16 58.7 18.9 0.14 13.1 0.3 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM79917.1 - 3.3e-12 46.1 24.4 0.034 14.6 0.3 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type OrsD PF12013.8 KFM79917.1 - 1e-05 26.0 16.3 0.055 13.9 0.3 5.1 4 1 1 5 5 5 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_11 PF16622.5 KFM79917.1 - 0.00027 20.6 7.9 0.19 11.5 0.0 4.9 5 0 0 5 5 5 2 zinc-finger C2H2-type Trm112p PF03966.16 KFM79917.1 - 0.00035 21.1 4.0 12 6.6 0.1 4.6 4 1 1 5 5 5 1 Trm112p-like protein VATC PF18716.1 KFM79917.1 - 0.01 15.6 16.9 0.047 13.6 0.2 5.4 6 0 0 6 6 6 0 Vms1-associating treble clef domain DUF2256 PF10013.9 KFM79917.1 - 0.056 13.6 10.5 12 6.1 0.2 5.5 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) Yippee-Mis18 PF03226.14 KFM79917.1 - 0.11 12.7 0.4 0.11 12.7 0.4 3.7 2 1 2 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-FPG_IleRS PF06827.14 KFM79917.1 - 0.25 11.2 8.5 45 4.0 0.0 5.1 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS HNH PF01844.23 KFM79917.1 - 1.8 8.8 14.3 19 5.5 0.4 5.3 5 0 0 5 5 5 0 HNH endonuclease TMCCDC2 PF15844.5 KFM79917.1 - 3.3 7.6 5.0 1.1 9.2 0.2 2.2 1 1 1 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 TF_Zn_Ribbon PF08271.12 KFM79917.1 - 8.7 6.0 12.2 2.3 7.8 0.1 4.1 4 0 0 4 4 4 0 TFIIB zinc-binding PBP PF01161.20 KFM79919.1 - 1.6e-06 28.4 0.0 2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RP1-2 PF12042.8 KFM79920.1 - 2.8e-293 961.1 815.4 3.7e-19 69.2 33.4 22.6 21 1 0 22 22 22 20 Tubuliform egg casing silk strands structural domain Spidroin_N PF16763.5 KFM79920.1 - 6.2e-44 149.0 9.9 6.2e-44 149.0 9.9 17.3 20 2 1 21 21 21 1 Major ampullate spidroin 1, spider silk protein 1, N-term Spidroin_MaSp PF11260.8 KFM79920.1 - 3.1e-14 53.0 10.4 3.1e-14 53.0 10.4 45.8 25 20 32 59 59 59 1 Major ampullate spidroin 1 and 2 AIRS PF00586.24 KFM79920.1 - 1.2e-13 51.6 91.9 6.1 7.6 0.3 21.6 21 1 1 22 22 22 7 AIR synthase related protein, N-terminal domain PTPA PF03095.15 KFM79920.1 - 2.3e-06 27.3 0.0 1.2e+02 2.0 0.0 10.3 14 0 0 14 14 14 0 Phosphotyrosyl phosphate activator (PTPA) protein Methyltransf_28 PF02636.17 KFM79920.1 - 0.00066 19.4 0.1 48 3.5 0.0 7.9 12 0 0 12 12 12 0 Putative S-adenosyl-L-methionine-dependent methyltransferase STAG PF08514.11 KFM79920.1 - 0.0015 18.4 1.1 1.8 8.5 0.0 3.3 2 0 0 2 2 2 2 STAG domain TPR_17 PF13431.6 KFM79920.1 - 3.5 8.2 20.7 4.4e+02 1.6 0.0 10.8 13 0 0 13 13 13 0 Tetratricopeptide repeat PBP PF01161.20 KFM79921.1 - 0.0081 16.5 0.2 0.011 16.1 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.20 KFM79922.1 - 1.1e-10 41.9 0.1 1.5e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ESF1 PF18209.1 KFM79923.1 - 0.038 13.9 6.8 0.038 13.9 6.8 1.8 2 0 0 2 2 2 0 Embryo surrounding factor 1 Gal-3-0_sulfotr PF06990.11 KFM79924.1 - 1.3e-52 179.0 1.7 1.8e-52 178.6 1.7 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase cwf21 PF08312.12 KFM79924.1 - 3.9 7.7 6.8 11 6.3 2.0 3.1 2 1 1 3 3 3 0 cwf21 domain CUE PF02845.16 KFM79925.1 - 0.0018 17.9 0.1 0.0036 17.0 0.1 1.5 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 KFM79925.1 - 0.028 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 UBA-like domain ABC2_membrane_3 PF12698.7 KFM79927.1 - 2e-38 132.4 16.2 2e-38 132.4 16.2 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 KFM79928.1 - 1.5e-27 96.8 0.0 2.9e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KFM79928.1 - 1.6e-22 80.1 11.3 2.1e-22 79.7 11.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KFM79928.1 - 1.1e-10 41.9 0.0 3.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 KFM79928.1 - 0.0043 16.4 7.1 0.0073 15.6 7.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.6 KFM79928.1 - 0.01 16.4 0.3 0.01 16.4 0.3 1.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KFM79928.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFM79928.1 - 0.17 11.7 0.2 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain VCPO_N PF17897.1 KFM79929.1 - 0.073 12.9 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain Methyltransf_34 PF11312.8 KFM79931.1 - 7.5e-15 55.0 0.1 1.4e-14 54.0 0.1 1.5 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase Methyltransf_34 PF11312.8 KFM79932.1 - 8.4e-08 31.8 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Methyltransf_34 PF11312.8 KFM79933.1 - 2.2e-11 43.6 0.0 4.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Homez PF11569.8 KFM79933.1 - 0.061 12.8 0.6 0.31 10.5 0.1 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Mito_carr PF00153.27 KFM79934.1 - 9.2e-63 208.2 3.6 4.5e-23 81.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldedh PF00171.22 KFM79935.1 - 4.6e-159 529.8 0.3 5.1e-159 529.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease PF00324.21 KFM79936.1 - 1.6e-42 145.7 29.3 7.8e-22 77.5 21.5 2.2 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KFM79936.1 - 6.8e-17 61.4 24.3 3.8e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 KFM79937.1 - 8e-49 166.8 2.0 6.8e-18 64.9 0.7 3.3 2 1 1 3 3 3 3 Solute carrier family 12 AA_permease PF00324.21 KFM79937.1 - 2.8e-12 46.0 0.4 3.5e-12 45.7 0.4 1.1 1 0 0 1 1 1 1 Amino acid permease EI24 PF07264.11 KFM79937.1 - 0.0092 16.2 2.2 0.011 16.0 0.9 1.7 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Gpi16 PF04113.14 KFM79938.1 - 5.2e-161 536.9 0.1 8.1e-160 532.9 0.1 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component SlyX PF04102.12 KFM79940.1 - 0.044 14.4 0.6 0.1 13.2 0.6 1.7 1 0 0 1 1 1 0 SlyX Noelin-1 PF12308.8 KFM79940.1 - 0.13 12.3 1.8 0.33 11.0 1.8 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein TMF_TATA_bd PF12325.8 KFM79940.1 - 0.2 11.9 7.3 1.4 9.1 2.4 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Ribosomal_S18 PF01084.20 KFM79943.1 - 9.2e-18 64.2 0.1 1.5e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 DUF630 PF04783.12 KFM79943.1 - 0.083 13.1 0.1 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF630) Yippee-Mis18 PF03226.14 KFM79944.1 - 9.4e-14 51.5 0.1 1.1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 KFM79944.1 - 0.0005 20.1 0.1 0.00064 19.8 0.1 1.1 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.8 KFM79944.1 - 0.016 15.4 0.1 0.022 15.0 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I Pox_polyA_pol_C PF12629.7 KFM79944.1 - 0.15 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase C-terminal domain IL17 PF06083.11 KFM79946.1 - 0.11 12.9 3.1 0.11 13.0 1.9 1.6 1 1 1 2 2 2 0 Interleukin-17 Ank_2 PF12796.7 KFM79948.1 - 7e-11 42.6 1.2 1.4e-06 28.8 0.5 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) TRP_2 PF08344.11 KFM79948.1 - 3e-07 30.5 2.4 5.6e-07 29.7 2.4 1.5 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_3 PF13606.6 KFM79948.1 - 0.00013 22.1 0.1 0.032 14.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KFM79948.1 - 0.00018 21.8 0.5 0.0013 19.1 0.0 2.4 2 1 1 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KFM79948.1 - 0.00093 19.5 0.0 0.0079 16.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM79948.1 - 0.00094 19.7 0.6 0.0071 16.9 0.3 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) OSTbeta PF15048.6 KFM79950.1 - 0.022 14.9 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Phage_holin_3_6 PF07332.11 KFM79950.1 - 0.027 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ATP1G1_PLM_MAT8 PF02038.16 KFM79950.1 - 0.15 11.5 11.4 1 8.8 2.1 3.1 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family SdpI PF13630.6 KFM79950.1 - 1.4 9.1 5.4 2.2 8.5 5.5 1.3 1 1 0 1 1 1 0 SdpI/YhfL protein family Synaptobrevin PF00957.21 KFM79951.1 - 0.031 14.1 0.7 7.1 6.5 0.1 2.4 2 0 0 2 2 2 0 Synaptobrevin G0-G1_switch_2 PF15103.6 KFM79951.1 - 0.075 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF1269 PF06897.12 KFM79953.1 - 0.0094 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) YqzH PF14164.6 KFM79953.1 - 0.13 12.3 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 YqzH-like protein Beta_elim_lyase PF01212.21 KFM79955.1 - 6.1e-62 209.5 0.3 7.8e-62 209.2 0.3 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFM79955.1 - 2.7e-05 23.3 0.0 3.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V RPN7 PF10602.9 KFM79956.1 - 1.9e-60 203.5 0.8 1.9e-60 203.5 0.8 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KFM79956.1 - 2.6e-19 69.7 3.6 4.1e-19 69.0 1.0 2.5 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KFM79956.1 - 0.0037 17.3 2.3 0.17 12.1 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM79956.1 - 0.018 14.7 0.3 0.13 12.0 0.0 2.6 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.28 KFM79956.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Drf_GBD PF06371.13 KFM79959.1 - 2.1e-11 43.8 0.1 2.4e-11 43.5 0.1 1.0 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF5578 PF17741.1 KFM79959.1 - 0.0027 17.2 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5578) DnaJ PF00226.31 KFM79960.1 - 1.2e-23 83.0 0.1 3.2e-23 81.6 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 KFM79960.1 - 3.5e-07 30.1 0.0 1.2e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Calsequestrin PF01216.17 KFM79960.1 - 0.062 12.3 0.3 0.71 8.8 0.0 2.3 2 0 0 2 2 2 0 Calsequestrin TPR_2 PF07719.17 KFM79961.1 - 1.5e-10 40.4 8.8 0.0053 16.8 0.3 4.1 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM79961.1 - 2e-10 40.0 5.0 0.0077 16.0 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM79961.1 - 5.5e-08 32.4 4.9 0.21 11.9 0.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM79961.1 - 4.7e-07 30.1 1.1 0.036 14.9 0.2 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM79961.1 - 1e-06 29.2 0.5 0.035 14.6 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM79961.1 - 1.3e-06 28.0 2.2 0.0061 16.2 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 KFM79961.1 - 4.3e-05 24.1 2.0 0.3 11.8 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM79961.1 - 0.00045 20.3 0.1 0.0077 16.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM79961.1 - 0.0059 16.8 6.1 0.071 13.3 1.0 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KFM79961.1 - 0.0094 15.4 0.5 0.016 14.6 0.5 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 KFM79961.1 - 0.013 15.8 1.0 0.064 13.7 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HCNGP PF07818.13 KFM79961.1 - 0.017 15.8 0.0 0.055 14.1 0.0 1.9 1 0 0 1 1 1 0 HCNGP-like protein TPR_15 PF13429.6 KFM79961.1 - 0.019 14.2 9.7 0.063 12.5 1.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM79961.1 - 0.086 13.1 5.9 1.1 9.6 0.5 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFM79961.1 - 0.12 12.9 3.1 0.25 11.8 0.4 2.2 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation PRP38_assoc PF12871.7 KFM79961.1 - 0.42 11.2 16.8 0.93 10.1 16.8 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DDE_Tnp_4 PF13359.6 KFM79962.1 - 2.6e-41 140.9 0.0 4.3e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease THAP PF05485.12 KFM79962.1 - 5.2e-18 65.7 7.4 1.3e-17 64.5 7.4 1.7 1 0 0 1 1 1 1 THAP domain HTH_Tnp_4 PF13613.6 KFM79962.1 - 1.3e-11 44.0 0.0 3e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KFM79962.1 - 1.5e-07 31.3 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain zf-H2C2_2 PF13465.6 KFM79963.1 - 3.4e-30 103.1 38.2 3e-08 33.7 0.2 7.8 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79963.1 - 6.2e-26 89.4 44.7 1.8e-06 28.1 0.8 7.5 8 0 0 8 8 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79963.1 - 5.3e-21 73.5 42.4 2.6e-05 24.7 0.4 7.8 8 1 1 9 9 7 5 C2H2-type zinc finger zf-met PF12874.7 KFM79963.1 - 9.4e-13 48.1 31.8 0.014 15.8 0.1 7.6 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM79963.1 - 3.9e-07 29.7 26.5 0.49 10.2 1.2 6.3 6 0 0 6 6 6 5 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM79963.1 - 4.1e-07 29.6 19.2 0.25 11.1 0.2 5.4 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM79963.1 - 3.6e-06 27.1 23.6 0.57 10.5 0.0 6.6 7 0 0 7 7 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM79963.1 - 0.00079 19.7 19.7 1.7 9.0 0.3 5.4 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFM79963.1 - 0.0021 18.0 35.3 0.0066 16.4 0.5 6.5 6 0 0 6 6 6 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFM79963.1 - 0.0039 16.7 15.8 10 5.8 0.0 6.2 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KFM79963.1 - 0.0055 16.7 32.0 0.43 10.6 0.3 6.5 2 1 4 6 6 6 3 BED zinc finger zf-Di19 PF05605.12 KFM79963.1 - 0.011 16.0 11.8 0.025 14.9 2.8 4.7 4 2 1 6 6 5 0 Drought induced 19 protein (Di19), zinc-binding YqzL PF14006.6 KFM79963.1 - 0.036 14.4 0.9 85 3.6 0.0 4.6 6 0 0 6 6 5 0 YqzL-like protein PyrI_C PF02748.15 KFM79963.1 - 0.041 13.8 8.8 0.39 10.6 0.4 3.7 1 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 KFM79963.1 - 0.12 12.5 24.6 0.14 12.3 1.6 5.6 3 3 2 6 6 6 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 KFM79963.1 - 0.2 11.5 2.3 6.8 6.6 0.1 3.8 2 1 2 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 KFM79963.1 - 0.22 12.2 11.2 2.7 8.7 6.1 4.2 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 KFM79963.1 - 0.29 11.2 9.9 5.2 7.1 3.2 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GAGA PF09237.11 KFM79963.1 - 0.39 10.6 12.1 2.6 7.9 0.0 4.4 4 2 2 6 6 6 0 GAGA factor Zf_RING PF16744.5 KFM79963.1 - 0.6 10.3 17.6 46 4.2 0.1 6.0 2 1 3 6 6 6 0 KIAA1045 RING finger zf-LYAR PF08790.11 KFM79963.1 - 2 8.4 17.6 2.5 8.1 0.1 5.0 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger TRAF6_Z2 PF18048.1 KFM79963.1 - 3.8 7.7 26.7 1.4 9.1 2.0 5.6 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 zf-Dof PF02701.15 KFM79963.1 - 4.2 7.6 20.8 14 5.9 0.2 5.3 3 1 2 5 5 5 0 Dof domain, zinc finger zinc_ribbon_15 PF17032.5 KFM79963.1 - 6 7.7 18.0 2.9 8.7 1.4 3.2 2 1 1 3 3 2 0 zinc-ribbon family Peptidase_M28 PF04389.17 KFM79964.1 - 1e-20 74.3 0.1 5.1e-19 68.7 0.0 2.7 4 0 0 4 4 4 1 Peptidase family M28 TFR_dimer PF04253.15 KFM79964.1 - 1.2e-17 64.1 0.0 2.4e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 KFM79964.1 - 1.3e-08 34.7 0.0 2.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KFM79964.1 - 2.2e-08 34.0 0.0 4.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RRM_1 PF00076.22 KFM79965.1 - 1.4e-45 153.0 5.8 1.9e-18 66.0 0.2 4.6 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM79965.1 - 3.3e-05 23.7 0.1 0.83 9.6 0.0 3.9 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KFM79965.1 - 0.00065 19.3 0.3 0.0028 17.3 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KFM79965.1 - 0.017 15.1 0.2 3.9 7.5 0.0 3.6 3 1 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Phage_TAC_13 PF16459.5 KFM79965.1 - 0.062 13.7 1.5 1.4 9.4 0.0 3.0 3 0 0 3 3 3 0 Phage tail assembly chaperone, TAC Asparaginase_2 PF01112.18 KFM79966.1 - 0.0051 15.9 2.6 0.0088 15.1 2.6 1.2 1 0 0 1 1 1 1 Asparaginase V_ATPase_I PF01496.19 KFM79966.1 - 0.033 12.1 4.8 0.047 11.6 4.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-FCS PF06467.14 KFM79966.1 - 0.074 13.0 7.6 0.54 10.2 7.6 2.3 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif CLN3 PF02487.17 KFM79966.1 - 4.9 6.1 7.9 12 4.8 7.9 1.6 1 0 0 1 1 1 0 CLN3 protein SAM_1 PF00536.30 KFM79967.1 - 2.8e-16 59.7 0.0 3.4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM79967.1 - 4.1e-09 36.4 0.0 5.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFM79967.1 - 0.0018 18.2 0.1 0.0032 17.4 0.1 1.4 1 1 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Mito_fiss_reg PF05308.11 KFM79967.1 - 5.5 7.0 7.4 7 6.7 7.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DEC-1_N PF04625.13 KFM79967.1 - 6.9 5.6 11.6 7.7 5.4 11.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-H2C2_2 PF13465.6 KFM79968.1 - 1.5e-76 249.6 107.8 1.3e-07 31.7 3.0 14.0 13 1 1 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM79968.1 - 7.5e-53 174.1 111.4 6.3e-05 23.2 2.4 12.4 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM79968.1 - 4.6e-43 142.2 105.1 0.00077 20.1 2.3 12.5 12 0 0 12 12 12 12 C2H2-type zinc finger zf-met PF12874.7 KFM79968.1 - 4.7e-21 74.5 88.9 0.0053 17.1 0.8 12.5 12 0 0 12 12 12 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM79968.1 - 5e-15 55.1 91.8 0.008 16.2 1.4 12.9 12 1 0 12 12 12 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM79968.1 - 3.1e-14 52.8 78.3 0.0071 16.6 0.9 12.5 11 1 1 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM79968.1 - 5e-07 29.6 39.2 0.13 12.4 0.1 11.6 9 2 3 12 12 12 2 Sec23/Sec24 zinc finger BolA PF01722.18 KFM79968.1 - 8.9e-06 25.9 29.6 1.2 9.5 0.7 8.1 2 2 3 7 7 7 4 BolA-like protein zf-C2HC_2 PF13913.6 KFM79968.1 - 0.0002 21.1 59.8 0.36 10.8 0.0 11.7 12 0 0 12 12 11 4 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM79968.1 - 0.00068 19.7 55.6 4 7.6 0.1 12.0 12 0 0 12 12 12 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 KFM79968.1 - 0.00084 19.1 47.1 4.2 7.3 0.3 11.6 2 1 10 12 12 12 2 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFM79968.1 - 0.001 18.8 84.1 0.042 13.6 1.1 11.8 12 0 0 12 12 12 5 zinc-finger C2H2-type Baculo_IE-1 PF05290.11 KFM79968.1 - 0.0029 17.6 43.1 0.66 9.9 5.8 8.2 1 1 4 5 5 5 2 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 KFM79968.1 - 0.0078 16.3 70.6 0.35 11.0 15.1 6.2 1 1 4 5 5 5 2 FYVE zinc finger ADK_lid PF05191.14 KFM79968.1 - 0.0097 15.9 47.2 0.41 10.7 1.4 7.6 6 2 1 7 7 7 4 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM79968.1 - 0.35 11.6 57.2 1.4 9.7 3.8 7.0 1 1 8 9 9 9 0 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM79968.1 - 0.39 10.8 57.0 1.7 8.8 9.8 5.7 1 1 6 7 7 7 0 Putative ribonucleoprotein zinc-finger pf C4 type GAGA PF09237.11 KFM79968.1 - 2.1 8.2 28.6 7.5 6.4 0.1 8.0 4 2 7 11 11 11 0 GAGA factor zf-DBF PF07535.12 KFM79968.1 - 2.1 8.5 64.8 12 6.1 0.4 12.0 11 1 1 12 12 12 0 DBF zinc finger DUF2039 PF10217.9 KFM79968.1 - 6.3 7.2 55.7 0.43 10.9 7.3 5.6 1 1 5 6 6 6 0 Uncharacterized conserved protein (DUF2039) DDE_Tnp_1_7 PF13843.6 KFM79969.1 - 8.7e-05 22.0 0.8 9.7e-05 21.8 0.8 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF4692 PF15763.5 KFM79971.1 - 4.2 7.8 6.4 0.49 10.8 1.4 1.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Tfb4 PF03850.14 KFM79972.1 - 2e-17 63.6 0.0 2.2e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Tfb4 PF03850.14 KFM79973.1 - 2e-59 201.3 5.5 2.3e-59 201.2 5.5 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Baculo_IE-1 PF05290.11 KFM79973.1 - 2.3 8.2 8.9 1.2 9.0 6.4 1.8 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Glyco_hydro_31 PF01055.26 KFM79974.1 - 9.2e-123 410.7 0.1 1.1e-122 410.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4550 PF15084.6 KFM79974.1 - 0.046 14.1 0.3 0.47 10.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) Tweety PF04906.13 KFM79975.1 - 3.1e-96 322.5 3.6 3.6e-96 322.3 3.6 1.0 1 0 0 1 1 1 1 Tweety Tetraspanin PF00335.20 KFM79975.1 - 5.4e-05 23.0 4.8 0.0022 17.8 1.0 2.4 2 0 0 2 2 2 2 Tetraspanin family Prominin PF05478.11 KFM79975.1 - 0.00015 19.9 1.6 0.00015 19.9 1.6 3.3 3 1 1 4 4 3 2 Prominin Wzy_C PF04932.15 KFM79975.1 - 0.016 14.8 0.4 4.2 7.0 0.1 2.5 2 0 0 2 2 2 0 O-Antigen ligase PhaP_Bmeg PF09602.10 KFM79975.1 - 0.022 14.7 5.0 2.8 7.8 1.9 2.2 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4131 PF13567.6 KFM79975.1 - 0.027 14.1 0.0 0.027 14.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF948 PF06103.11 KFM79975.1 - 0.072 13.4 0.1 0.072 13.4 0.1 3.9 5 1 0 5 5 3 0 Bacterial protein of unknown function (DUF948) Phasin PF05597.11 KFM79975.1 - 0.15 12.1 1.9 0.43 10.6 0.5 2.3 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1359 PF07097.11 KFM79975.1 - 0.16 12.2 5.5 0.18 12.0 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) PLAC9 PF15205.6 KFM79975.1 - 0.19 12.1 0.3 12 6.3 0.1 2.5 2 0 0 2 2 2 0 Placenta-specific protein 9 HsbA PF12296.8 KFM79975.1 - 0.28 11.6 2.4 15 6.1 0.3 2.4 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF16 PF01519.16 KFM79975.1 - 2.6 8.6 9.0 7 7.2 3.1 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 KFM79975.1 - 4.4 7.7 8.6 15 6.0 0.3 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Duo1 PF08651.10 KFM79975.1 - 6.1 6.7 12.5 4.6 7.1 1.5 4.1 2 2 2 5 5 5 0 DASH complex subunit Duo1 Fib_alpha PF08702.10 KFM79975.1 - 9.4 6.4 9.2 3.1 8.0 2.6 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5484 PF17583.2 KFM79976.1 - 0.0048 16.5 0.0 38 4.0 0.0 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5484) WWamide PF08258.11 KFM79976.1 - 0.062 13.5 0.3 4.4e+02 2.0 0.0 4.2 4 0 0 4 4 4 0 WWamide peptide YmzC PF14157.6 KFM79976.1 - 0.084 13.0 4.6 37 4.5 0.1 3.4 3 0 0 3 3 3 0 YmzC-like protein CPSase_C PF18302.1 KFM79976.1 - 0.18 12.2 5.1 6.3 7.6 0.2 4.5 4 0 0 4 4 4 0 Carbamoyl phosphate synthetase C-terminal domain DUF1891 PF09004.10 KFM79976.1 - 0.43 10.2 5.8 3.8 7.2 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1891) Arc_trans_TRASH PF08394.10 KFM79976.1 - 0.43 10.9 1.4 22 5.5 0.1 3.6 4 0 0 4 4 4 0 Archaeal TRASH domain PX PF00787.24 KFM79976.1 - 1.3 9.0 14.6 6.2 6.8 0.5 3.4 1 1 2 3 3 3 0 PX domain TFB6 PF17110.5 KFM79976.1 - 4.4 7.0 8.5 56 3.4 0.1 3.7 1 1 3 4 4 4 0 Subunit 11 of the general transcription factor TFIIH DENN PF02141.21 KFM79981.1 - 0.059 13.3 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 DENN (AEX-3) domain PH PF00169.29 KFM79985.1 - 1.4e-10 41.6 0.0 4.2e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 PH domain C2 PF00168.30 KFM79985.1 - 1.1e-05 25.7 0.0 2.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain PH_13 PF16652.5 KFM79985.1 - 0.0088 15.9 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFM79985.1 - 0.023 15.0 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Cep57_CLD_2 PF14197.6 KFM79985.1 - 1.6 8.9 5.5 3.2 7.9 0.9 3.5 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 PP1_bind PF15276.6 KFM79986.1 - 4.7e-13 49.2 1.7 3.1e-12 46.6 1.0 2.8 3 0 0 3 3 3 1 Protein phosphatase 1 binding FHA PF00498.26 KFM79986.1 - 9.4e-07 29.1 0.0 2.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM79986.1 - 3.7e-05 24.0 0.0 8.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Remorin_N PF03766.13 KFM79986.1 - 0.89 9.7 12.2 13 5.9 0.6 4.2 2 1 1 3 3 3 0 Remorin, N-terminal region Guanylate_cyc PF00211.20 KFM79989.1 - 9.8e-32 110.0 0.0 1.1e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFM79990.1 - 4.7e-48 163.5 5.1 1.9e-29 102.7 0.2 2.3 1 1 1 2 2 2 2 Heme NO binding associated HNOB PF07700.15 KFM79990.1 - 4.7e-32 111.2 0.0 7.4e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding Barstar PF01337.18 KFM79990.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Barstar (barnase inhibitor) HNOBA PF07701.14 KFM79992.1 - 8.2e-15 54.8 0.4 1.2e-14 54.3 0.4 1.2 1 0 0 1 1 1 1 Heme NO binding associated TonB_2 PF13103.6 KFM79992.1 - 0.053 13.8 0.0 0.088 13.1 0.0 1.3 1 0 0 1 1 1 0 TonB C terminal C2 PF00168.30 KFM79994.1 - 6.5e-50 167.7 0.1 3.2e-16 59.5 0.0 4.7 5 0 0 5 5 5 4 C2 domain FerB PF08150.12 KFM79994.1 - 2.8e-30 104.7 0.0 8.7e-30 103.2 0.0 1.9 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.12 KFM79994.1 - 1.5e-20 73.0 1.3 4.1e-20 71.6 1.3 1.8 1 0 0 1 1 1 1 FerI (NUC094) domain BSP_II PF05432.11 KFM79994.1 - 0.067 12.9 4.4 0.11 12.1 4.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) UPF0640 PF15114.6 KFM79994.1 - 0.11 12.3 0.7 0.45 10.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 C2 PF00168.30 KFM79995.1 - 0.0015 18.8 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain FA_hydroxylase PF04116.13 KFM79998.1 - 1.9e-26 93.0 15.1 1.9e-26 93.0 15.1 2.7 3 1 1 4 4 4 1 Fatty acid hydroxylase superfamily Ion_trans_2 PF07885.16 KFM80000.1 - 0.0065 16.4 0.1 0.0079 16.1 0.1 1.2 1 0 0 1 1 1 1 Ion channel EHD_N PF16880.5 KFM80000.1 - 0.015 15.1 0.2 0.053 13.4 0.4 1.8 2 0 0 2 2 2 0 N-terminal EH-domain containing protein Shisa PF13908.6 KFM80001.1 - 5.4e-06 26.8 2.1 7.4e-06 26.3 0.6 2.0 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator TMEM52 PF14979.6 KFM80001.1 - 0.00064 19.7 0.3 0.00064 19.7 0.3 1.9 2 0 0 2 2 2 1 Transmembrane 52 FAM176 PF14851.6 KFM80001.1 - 0.027 14.1 0.3 0.056 13.1 0.3 1.5 1 0 0 1 1 1 0 FAM176 family GAF PF01590.26 KFM80003.1 - 6.9e-06 26.7 0.0 8e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KFM80003.1 - 0.0015 18.8 0.0 0.0017 18.6 0.0 1.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KFM80003.1 - 0.03 14.7 0.0 0.033 14.5 0.0 1.1 1 0 0 1 1 1 0 GAF domain Auto_anti-p27 PF06677.12 KFM80003.1 - 1.4 9.2 7.4 2.5 8.3 7.4 1.5 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PDEase_I PF00233.19 KFM80004.1 - 4e-75 252.6 1.7 5.4e-75 252.2 1.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFM80004.1 - 8e-16 58.9 0.0 1.4e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KFM80004.1 - 2.7e-07 30.9 0.0 5.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KFM80004.1 - 7.8e-07 29.5 0.0 1.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 GAF domain Glyco_transf_49 PF13896.6 KFM80006.1 - 3.8e-99 332.2 3.2 4.5e-99 331.9 3.2 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan PDEase_I PF00233.19 KFM80007.1 - 3e-14 53.3 0.3 3.2e-14 53.3 0.3 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DEAD PF00270.29 KFM80008.1 - 5.8e-45 153.2 0.0 9.4e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM80008.1 - 9.6e-23 80.6 0.0 4.3e-22 78.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFM80008.1 - 5.7e-13 48.9 0.8 1.2e-12 47.8 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFM80008.1 - 2.6e-10 40.6 0.2 1e-09 38.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFM80008.1 - 0.013 14.7 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KFM80008.1 - 0.016 15.5 0.2 0.064 13.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain Peptidase_M60 PF13402.6 KFM80010.1 - 0.056 13.0 0.2 0.064 12.8 0.2 1.2 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like DUF4178 PF13785.6 KFM80010.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4178) DUF3022 PF11226.8 KFM80010.1 - 0.19 12.2 2.7 0.3 11.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) FUSC PF04632.12 KFM80010.1 - 0.24 9.9 3.0 0.36 9.3 3.0 1.2 1 1 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.12 KFM80010.1 - 0.6 10.5 4.8 2.6 8.5 4.8 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Neur_chan_LBD PF02931.23 KFM80011.1 - 1.5e-16 60.6 0.0 1.7e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFM80012.1 - 4.5e-10 40.0 0.0 5.5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region zf-H2C2_2 PF13465.6 KFM80013.1 - 1.4e-12 47.4 10.4 1.1e-05 25.6 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80013.1 - 6.4e-11 42.1 7.2 1.8e-05 24.9 0.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80013.1 - 6.7e-11 42.1 6.0 0.00014 22.4 2.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM80013.1 - 1.9e-06 28.0 1.8 0.06 13.8 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM80013.1 - 2.7e-05 23.8 2.1 0.012 15.4 0.1 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM80013.1 - 0.00012 22.3 0.2 0.66 10.3 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM80013.1 - 0.00038 20.2 7.3 0.13 12.0 2.2 2.9 2 1 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KFM80013.1 - 0.0047 17.3 0.1 0.0047 17.3 0.1 2.6 2 1 1 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 KFM80013.1 - 0.017 14.9 3.1 0.019 14.8 0.1 2.1 1 1 1 2 2 2 0 GAGA factor zf-C2H2_6 PF13912.6 KFM80013.1 - 0.021 14.8 0.2 0.021 14.8 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KFM80013.1 - 0.044 13.8 1.2 0.1 12.6 0.1 2.1 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_9 PF16293.5 KFM80013.1 - 0.076 12.9 1.2 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFM80013.1 - 0.1 12.9 1.8 3.8 7.9 0.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 KFM80013.1 - 0.19 12.0 5.1 0.49 10.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon Zn_ribbon_SprT PF17283.2 KFM80013.1 - 0.32 10.9 4.7 0.89 9.5 4.6 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Surp PF01805.20 KFM80014.1 - 2e-17 62.9 0.5 4.6e-17 61.7 0.5 1.6 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 KFM80014.1 - 1.3e-14 54.8 1.9 2.2e-14 54.0 0.7 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. G-patch PF01585.23 KFM80014.1 - 6e-12 45.3 0.3 1.2e-11 44.3 0.3 1.6 1 0 0 1 1 1 1 G-patch domain DUF3921 PF13060.6 KFM80014.1 - 0.11 12.6 0.7 0.28 11.3 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) DUF2610 PF11020.8 KFM80014.1 - 0.91 9.4 3.4 0.9 9.5 1.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2610) 7tm_3 PF00003.22 KFM80015.1 - 1.2e-59 201.9 15.1 1.9e-59 201.3 15.1 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 KFM80015.1 - 3e-14 52.9 0.6 5.7e-14 52.0 0.6 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region Gln_deamidase_2 PF18626.1 KFM80015.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutaminase DUF3995 PF13160.6 KFM80015.1 - 0.49 10.8 7.6 0.051 13.9 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) Halogen_Hydrol PF10112.9 KFM80015.1 - 0.54 10.3 0.0 0.54 10.3 0.0 2.3 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein YabA PF06156.13 KFM80015.1 - 6.4 7.5 5.5 1.9 9.2 1.6 2.1 3 0 0 3 3 3 0 Initiation control protein YabA ANF_receptor PF01094.28 KFM80016.1 - 1.7e-08 34.0 0.0 1.9e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KFM80016.1 - 0.02 14.5 0.0 0.025 14.3 0.0 1.0 1 0 0 1 1 1 0 Periplasmic binding protein COA2 PF17051.5 KFM80016.1 - 0.09 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 VPS9 PF02204.18 KFM80017.1 - 1.1e-17 64.1 0.5 3.3e-17 62.6 0.1 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFM80017.1 - 0.028 14.7 0.1 0.059 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) RasGAP PF00616.19 KFM80019.1 - 1.4e-26 93.5 0.0 4.9e-26 91.7 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF1697 PF08002.11 KFM80019.1 - 0.1 13.1 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) dDENN PF03455.19 KFM80021.1 - 8.8e-11 41.6 5.0 9.2e-11 41.6 3.5 1.8 2 0 0 2 2 2 1 dDENN domain DUF1690 PF07956.11 KFM80021.1 - 0.03 14.8 0.1 0.04 14.3 0.1 1.3 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF1409 PF07197.12 KFM80021.1 - 0.05 13.5 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) Prominin PF05478.11 KFM80021.1 - 0.059 11.3 0.5 0.066 11.2 0.5 1.2 1 0 0 1 1 1 0 Prominin zf-H2C2_2 PF13465.6 KFM80025.1 - 1.2e-14 53.9 30.7 0.0041 17.5 0.9 5.9 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM80025.1 - 1.3e-14 53.7 28.0 0.0019 18.9 3.4 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM80025.1 - 4e-12 45.9 27.3 0.0046 17.3 0.1 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM80025.1 - 1.7e-07 31.3 10.7 0.12 12.7 0.5 4.8 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM80025.1 - 4.4e-06 26.6 31.0 0.09 12.8 0.6 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-Di19 PF05605.12 KFM80025.1 - 8.9e-05 22.7 12.6 0.012 15.9 1.8 2.7 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.6 KFM80025.1 - 0.001 19.0 12.6 5.3 7.1 0.1 5.0 5 0 0 5 5 5 1 zinc-ribbon domain zf-met PF12874.7 KFM80025.1 - 0.0015 18.8 23.3 0.27 11.7 0.2 4.3 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 KFM80025.1 - 0.006 17.3 12.5 0.5 11.1 4.6 3.0 2 1 0 2 2 2 2 zinc-ribbon family PHD_4 PF16866.5 KFM80025.1 - 0.0084 16.2 8.7 0.13 12.3 0.5 3.0 3 0 0 3 3 3 2 PHD-finger zf-DNA_Pol PF08996.10 KFM80025.1 - 0.0095 15.7 11.6 0.01 15.6 1.3 2.4 1 1 2 3 3 3 2 DNA Polymerase alpha zinc finger LIM_bind PF01803.16 KFM80025.1 - 0.012 15.2 0.2 0.012 15.2 0.2 1.6 2 0 0 2 2 2 0 LIM-domain binding protein GATA PF00320.27 KFM80025.1 - 0.027 14.1 0.5 0.027 14.1 0.5 4.0 3 2 1 4 4 4 0 GATA zinc finger zf-C2H2_3rep PF18868.1 KFM80025.1 - 0.083 13.6 12.4 4.3 8.0 0.3 3.9 1 1 4 5 5 5 0 Zinc finger C2H2-type, 3 repeats Zn_ribbon_SprT PF17283.2 KFM80025.1 - 0.095 12.6 17.4 0.14 12.0 1.0 3.5 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 KFM80025.1 - 0.13 12.0 25.2 0.22 11.3 0.3 4.7 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-MYST PF17772.1 KFM80025.1 - 0.14 11.8 12.5 3.1 7.5 0.2 4.1 3 2 1 5 5 5 0 MYST family zinc finger domain FYDLN_acid PF09538.10 KFM80025.1 - 0.21 12.3 3.9 2.1 9.0 0.2 3.4 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) LIM PF00412.22 KFM80025.1 - 0.3 11.4 17.6 0.4 10.9 1.3 3.7 1 1 3 4 4 4 0 LIM domain zf-FCS PF06467.14 KFM80025.1 - 0.3 11.1 0.1 0.3 11.1 0.1 3.4 3 1 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-RRPl_C4 PF17026.5 KFM80025.1 - 0.39 10.8 14.7 2.4 8.3 6.5 2.3 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-HIT PF04438.16 KFM80025.1 - 0.59 10.0 22.7 1.4 8.9 0.3 5.1 5 0 0 5 5 5 0 HIT zinc finger Zn-ribbon_8 PF09723.10 KFM80025.1 - 0.66 10.1 16.9 52 4.1 7.9 4.3 1 1 3 4 4 4 0 Zinc ribbon domain DUF2256 PF10013.9 KFM80025.1 - 0.87 9.8 0.1 0.87 9.8 0.1 4.2 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Actin_micro PF17003.5 KFM80025.1 - 0.89 8.7 14.9 0.2 10.8 2.9 3.3 1 1 1 2 2 2 0 Putative actin-like family FYVE PF01363.21 KFM80025.1 - 1.1 9.5 21.0 3.8 7.7 5.3 3.5 1 1 2 3 3 3 0 FYVE zinc finger C1_2 PF03107.16 KFM80025.1 - 1.4 9.3 26.4 12 6.3 4.7 4.9 3 2 0 3 3 3 0 C1 domain PHD PF00628.29 KFM80025.1 - 1.6 8.7 17.3 1.8 8.5 2.8 3.9 3 1 1 4 4 4 0 PHD-finger C1_4 PF07975.12 KFM80025.1 - 1.9 8.8 18.6 1.5 9.1 3.5 3.5 2 2 0 3 3 3 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 KFM80025.1 - 2.2 8.2 11.9 2.2 8.3 0.1 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM80025.1 - 4.8 7.2 12.4 3.2 7.8 0.8 3.6 3 2 1 4 4 4 0 Adenylate kinase, active site lid HNH PF01844.23 KFM80025.1 - 6.1 7.1 14.2 5.6 7.2 0.1 4.3 5 0 0 5 5 5 0 HNH endonuclease Endonuclease_7 PF02945.15 KFM80025.1 - 8.6 6.4 9.2 2e+02 2.0 9.2 2.4 1 1 0 1 1 1 0 Recombination endonuclease VII VirE_N PF08800.10 KFM80026.1 - 0.078 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 VirE N-terminal domain EGF PF00008.27 KFM80028.1 - 9.7e-63 208.0 124.2 4.8e-11 42.7 4.5 9.6 9 0 0 9 9 9 9 EGF-like domain hEGF PF12661.7 KFM80028.1 - 2e-46 155.1 108.3 1.2e-08 35.3 6.4 10.9 11 0 0 11 11 11 8 Human growth factor-like EGF EGF_CA PF07645.15 KFM80028.1 - 1.6e-19 69.8 120.1 0.00016 21.8 9.7 9.6 4 3 5 9 9 9 7 Calcium-binding EGF domain EGF_2 PF07974.13 KFM80028.1 - 2e-18 66.4 139.0 9.8e-05 22.6 6.3 9.7 9 0 0 9 9 9 9 EGF-like domain FXa_inhibition PF14670.6 KFM80028.1 - 9.3e-08 32.2 104.8 0.12 12.6 4.3 9.4 4 2 5 9 9 9 6 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFM80028.1 - 1.6e-06 28.2 112.2 0.0067 16.6 6.0 9.9 8 3 2 10 10 10 7 EGF domain Laminin_EGF PF00053.24 KFM80028.1 - 4.5e-05 23.5 110.3 2.3 8.4 7.2 9.5 2 1 7 9 9 9 4 Laminin EGF domain cEGF PF12662.7 KFM80028.1 - 0.021 14.8 108.5 0.057 13.4 5.4 11.9 10 4 0 10 10 10 0 Complement Clr-like EGF-like TPR_2 PF07719.17 KFM80029.1 - 1.1e-14 53.2 3.0 1.1e-05 25.2 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM80029.1 - 7.3e-12 45.4 4.5 0.00011 22.5 0.8 3.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM80029.1 - 1.4e-10 41.6 0.1 1.9e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM80029.1 - 6.6e-10 38.4 8.2 0.00063 19.5 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM80029.1 - 8.2e-10 38.1 6.0 0.00035 20.5 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM80029.1 - 3.7e-07 29.7 0.4 0.0096 15.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM80029.1 - 6.9e-06 25.8 3.7 0.017 15.0 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM80029.1 - 3.3e-05 23.4 0.2 0.00035 20.1 0.0 2.2 2 0 0 2 2 2 1 MalT-like TPR region TPR_9 PF13371.6 KFM80029.1 - 5.1e-05 23.3 0.0 0.0043 17.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM80029.1 - 7.5e-05 22.8 0.3 0.023 15.1 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KFM80029.1 - 7.6e-05 22.3 0.2 0.00011 21.7 0.2 1.3 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_15 PF13429.6 KFM80029.1 - 0.00024 20.4 0.1 0.00051 19.3 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat RPN7 PF10602.9 KFM80029.1 - 0.00026 20.7 0.1 0.0067 16.1 0.1 2.5 1 1 2 3 3 3 1 26S proteasome subunit RPN7 TPR_16 PF13432.6 KFM80029.1 - 0.00037 21.1 0.1 0.019 15.6 0.1 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM80029.1 - 0.00057 20.5 0.0 1.3 10.0 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM80029.1 - 0.00093 19.4 3.0 0.091 13.0 0.5 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 EST1_DNA_bind PF10373.9 KFM80029.1 - 0.0024 17.4 0.6 0.055 12.9 0.1 2.2 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain TPR_11 PF13414.6 KFM80029.1 - 0.0039 16.8 2.4 0.33 10.7 0.0 3.0 2 1 1 3 3 3 1 TPR repeat DUF410 PF04190.13 KFM80029.1 - 0.016 15.0 0.3 0.02 14.7 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF410) TPR_6 PF13174.6 KFM80029.1 - 0.025 15.2 1.2 56 4.7 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KFM80029.1 - 0.047 13.8 1.5 1.2 9.2 1.2 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 IL28A PF15177.6 KFM80029.1 - 0.098 12.5 0.7 0.42 10.5 0.1 2.2 3 0 0 3 3 3 0 Interleukin-28A DUF4869 PF16163.5 KFM80030.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) DEAD PF00270.29 KFM80031.1 - 1.3e-37 129.3 0.0 2.5e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM80031.1 - 6e-21 74.9 0.1 1.5e-20 73.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM80031.1 - 4.1e-06 26.9 3.8 1.7e-05 24.9 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFM80031.1 - 0.045 14.0 0.2 9.3 6.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain PPI_Ypi1 PF07491.11 KFM80032.1 - 8.6e-24 83.1 5.0 1.2e-23 82.7 5.0 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor zf-H2C2_5 PF13909.6 KFM80033.1 - 4.1e-06 26.4 3.8 4.1e-06 26.4 3.8 1.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM80033.1 - 0.0008 19.7 5.3 0.0014 19.0 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80033.1 - 0.0018 18.9 3.6 0.0018 18.9 3.6 1.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM80033.1 - 0.0037 17.6 8.4 0.015 15.7 0.7 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-4CXXC_R1 PF10497.9 KFM80033.1 - 0.031 14.5 0.1 0.031 14.5 0.1 1.0 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 T4_baseplate PF12322.8 KFM80033.1 - 0.071 12.6 0.1 0.072 12.6 0.1 1.0 1 0 0 1 1 1 0 T4 bacteriophage base plate protein HD_4 PF13328.6 KFM80034.1 - 3.3e-22 78.9 0.0 3.9e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 KFM80034.1 - 2.8e-05 24.3 0.2 0.00015 22.0 0.2 2.2 1 1 0 1 1 1 1 HD domain HTH_Tnp_Tc5 PF03221.16 KFM80035.1 - 0.0002 21.3 0.0 0.0046 17.0 0.0 2.3 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain MEDS PF14417.6 KFM80035.1 - 0.028 14.2 0.0 0.043 13.7 0.0 1.3 1 1 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain COX15-CtaA PF02628.15 KFM80037.1 - 4.5e-81 272.4 14.4 7.8e-81 271.7 5.1 2.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein Zip PF02535.22 KFM80038.1 - 1.1e-28 100.5 1.1 1.2e-28 100.4 1.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DLP_helical PF18709.1 KFM80038.1 - 0.26 10.5 0.2 0.35 10.0 0.2 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain Zip PF02535.22 KFM80039.1 - 4.9 6.3 7.9 0.083 12.1 1.0 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter DDE_3 PF13358.6 KFM80042.1 - 7.6e-07 29.0 0.0 9.2e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.18 KFM80042.1 - 2.2e-06 27.4 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) IBR PF01485.21 KFM80044.1 - 2.3e-19 69.4 35.2 5.9e-15 55.2 11.1 4.1 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFM80044.1 - 0.0045 17.3 6.1 0.0045 17.3 6.1 4.1 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 KFM80044.1 - 0.0053 16.7 8.5 0.0053 16.7 8.5 4.2 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM80044.1 - 0.024 14.7 5.1 0.024 14.7 5.1 3.6 3 1 0 3 3 3 0 RING-type zinc-finger PROCT PF08084.11 KFM80044.1 - 0.031 14.2 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 PROCT (NUC072) domain ADIP PF11559.8 KFM80044.1 - 0.44 10.6 5.6 0.14 12.2 1.6 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Syntaxin_2 PF14523.6 KFM80046.1 - 0.00025 21.4 0.0 0.00045 20.5 0.0 1.4 1 0 0 1 1 1 1 Syntaxin-like protein TipAS PF07739.13 KFM80046.1 - 0.033 14.7 0.0 9.5 6.8 0.0 2.3 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain ENTH PF01417.20 KFM80048.1 - 2.7e-34 117.9 0.1 3.4e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFM80048.1 - 5.9e-05 22.2 0.0 7.1e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KFM80048.1 - 0.0025 17.6 0.0 0.0034 17.2 0.0 1.3 1 1 0 1 1 1 1 VHS domain DUF713 PF05218.14 KFM80048.1 - 0.017 14.8 0.0 0.019 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF713) UCR_UQCRX_QCR9 PF05365.12 KFM80048.1 - 0.028 14.3 0.3 0.05 13.5 0.3 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Hemopexin PF00045.19 KFM80049.1 - 2.8e-29 100.8 8.6 1.5e-13 50.4 0.6 3.1 3 0 0 3 3 3 3 Hemopexin Glyco_transf_29 PF00777.18 KFM80051.1 - 4.6e-20 72.1 0.4 1.2e-19 70.8 0.0 1.8 2 1 0 2 2 2 1 Glycosyltransferase family 29 (sialyltransferase) Sushi PF00084.20 KFM80052.1 - 3.6e-76 251.6 64.7 1.1e-10 41.9 1.1 12.4 12 0 0 12 12 12 12 Sushi repeat (SCR repeat) HRM PF02793.22 KFM80052.1 - 0.0039 17.4 0.9 0.0039 17.4 0.9 7.4 8 0 0 8 8 8 1 Hormone receptor domain Ig_3 PF13927.6 KFM80052.1 - 0.013 16.0 2.8 0.038 14.6 0.1 3.2 3 0 0 3 3 3 0 Immunoglobulin domain MIP PF00230.20 KFM80053.1 - 3.3e-68 229.8 9.4 3.9e-68 229.5 9.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein CcmF_C PF16327.5 KFM80053.1 - 0.0073 15.6 1.4 0.011 15.0 1.1 1.3 1 1 0 1 1 1 1 Cytochrome c-type biogenesis protein CcmF C-terminal Toxin_28 PF08115.11 KFM80053.1 - 0.16 11.8 0.2 0.3 11.0 0.2 1.4 1 0 0 1 1 1 0 SFI toxin family UDPGP PF01704.18 KFM80054.1 - 2e-190 632.8 0.0 2.4e-190 632.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PTR PF12789.7 KFM80054.1 - 0.29 11.2 1.3 1.3 9.2 0.5 2.4 2 0 0 2 2 2 0 Phage tail repeat like TB2_DP1_HVA22 PF03134.19 KFM80055.1 - 8.6e-27 92.9 10.6 1.4e-26 92.2 10.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SPT6_acidic PF14632.6 KFM80055.1 - 0.78 10.4 12.4 0.53 10.9 3.1 2.2 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Prion PF00377.18 KFM80056.1 - 0.093 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Peptidase_M13_N PF05649.13 KFM80057.1 - 2.9e-113 379.4 0.2 1.3e-112 377.3 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM80057.1 - 1.7e-71 240.1 0.0 2.6e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 bHLH-MYC_N PF14215.6 KFM80061.1 - 0.012 15.8 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Dynamin_M PF01031.20 KFM80061.1 - 0.073 12.3 0.2 0.085 12.1 0.2 1.1 1 0 0 1 1 1 0 Dynamin central region Ank_2 PF12796.7 KFM80062.1 - 1.1e-08 35.6 0.0 1.3e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM80062.1 - 3.1e-07 30.6 0.0 4.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM80062.1 - 1.4e-06 28.2 0.0 0.0051 17.2 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFM80062.1 - 1.6e-06 28.5 0.1 0.0003 21.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM80062.1 - 1.8e-05 25.0 0.0 0.0022 18.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat R3H PF01424.22 KFM80063.1 - 4.4e-13 49.0 0.1 8.4e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 R3H domain ATPase PF06745.13 KFM80063.1 - 0.00025 20.5 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 KFM80063.1 - 0.00089 18.4 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KFM80063.1 - 0.0054 17.1 0.0 0.0081 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM80063.1 - 0.011 16.0 0.0 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KFM80063.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 KFM80063.1 - 0.018 15.5 0.1 0.044 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFM80063.1 - 0.027 14.2 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 KFM80063.1 - 0.04 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 KFM80063.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KFM80063.1 - 0.087 13.2 0.1 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 KFM80063.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KFM80063.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KFM80063.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KFM80063.1 - 0.15 12.5 0.2 0.91 10.0 0.2 2.1 1 1 1 2 2 2 0 ABC transporter Y_phosphatase PF00102.27 KFM80064.1 - 7.3e-70 235.2 0.0 1.4e-69 234.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM80064.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 KFM80064.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PAP_assoc PF03828.19 KFM80065.1 - 3.4e-15 56.0 0.0 6.6e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFM80065.1 - 0.00013 22.2 0.1 0.00029 21.1 0.1 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KFM80065.1 - 0.012 15.6 0.1 0.033 14.3 0.1 1.8 1 1 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Lung_7-TM_R PF06814.13 KFM80066.1 - 6.8e-54 183.1 1.3 8.4e-54 182.8 1.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 KFM80066.1 - 0.00057 19.4 3.1 0.00086 18.8 3.1 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 KFM80067.1 - 1.2e-10 41.2 4.4 1.4e-10 40.9 4.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor K_trans PF02705.16 KFM80067.1 - 0.085 11.4 0.0 0.085 11.4 0.0 1.0 1 0 0 1 1 1 0 K+ potassium transporter SH3_1 PF00018.28 KFM80068.1 - 0.0031 17.1 0.0 0.0079 15.8 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFM80068.1 - 0.041 13.7 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain MSC PF09402.10 KFM80069.1 - 2.6e-19 69.9 1.0 3.9e-19 69.3 0.6 1.4 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain LEM PF03020.15 KFM80069.1 - 4.7e-14 51.7 0.0 9.2e-14 50.7 0.0 1.5 1 0 0 1 1 1 1 LEM domain RBM39linker PF15519.6 KFM80069.1 - 0.00099 20.1 0.0 0.0038 18.3 0.0 2.0 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein DUF2207 PF09972.9 KFM80069.1 - 0.034 12.9 0.1 0.88 8.3 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2681 PF10883.8 KFM80069.1 - 0.28 11.6 2.5 13 6.3 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2681) Sushi PF00084.20 KFM80070.1 - 5.4e-15 55.7 15.3 5.4e-07 30.1 0.9 4.0 4 0 0 4 4 4 2 Sushi repeat (SCR repeat) F5_F8_type_C PF00754.25 KFM80070.1 - 2.3e-06 27.7 0.0 4e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 F5/8 type C domain Amnionless PF14828.6 KFM80070.1 - 0.0003 19.8 0.0 0.00046 19.1 0.0 1.2 1 0 0 1 1 1 1 Amnionless Sid-5 PF17204.3 KFM80070.1 - 0.0037 17.4 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 Sid-5 family OAD_gamma PF04277.13 KFM80070.1 - 0.0096 16.5 0.1 0.022 15.3 0.1 1.5 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain HRM PF02793.22 KFM80070.1 - 0.018 15.4 6.4 8.5 6.8 0.1 3.6 2 1 1 3 3 3 0 Hormone receptor domain Tnp_22_dsRBD PF17490.2 KFM80070.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain EphA2_TM PF14575.6 KFM80070.1 - 0.22 12.4 0.5 0.59 11.1 0.5 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 KFM80070.1 - 0.55 10.3 2.6 1.1 9.4 2.6 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Patatin PF01734.22 KFM80072.1 - 0.0023 18.1 0.0 0.0041 17.3 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Melibiase_2 PF16499.5 KFM80076.1 - 0.013 14.7 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Alpha galactosidase A Thymopoietin PF08198.11 KFM80076.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Thymopoietin protein Bestrophin PF01062.21 KFM80077.1 - 0.024 14.1 0.1 0.024 14.1 0.1 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel fn3 PF00041.21 KFM80079.1 - 0.0083 16.4 0.1 0.022 15.1 0.1 1.7 1 1 0 1 1 1 1 Fibronectin type III domain HS1_rep PF02218.15 KFM80080.1 - 0.00042 20.6 2.6 0.00078 19.7 2.6 1.5 1 0 0 1 1 1 1 Repeat in HS1/Cortactin HS1_rep PF02218.15 KFM80081.1 - 1.1e-53 179.2 16.0 4.7e-19 68.4 0.3 4.6 4 0 0 4 4 4 4 Repeat in HS1/Cortactin SH3_1 PF00018.28 KFM80081.1 - 1.6e-13 50.0 0.5 2.9e-13 49.2 0.5 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM80081.1 - 1.1e-09 38.0 0.3 2.2e-09 37.0 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM80081.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SOBP PF15279.6 KFM80081.1 - 0.034 14.8 11.5 0.048 14.3 11.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TMEM210 PF15195.6 KFM80081.1 - 0.16 12.4 0.1 15 6.1 0.0 2.8 1 1 2 3 3 3 0 TMEM210 family FOG_N PF15888.5 KFM80081.1 - 0.29 11.5 1.9 6.6 7.1 0.4 2.3 2 0 0 2 2 2 0 Folded gastrulation N-terminus Casc1_N PF15927.5 KFM80081.1 - 8.6 6.0 23.2 2.6 7.7 20.6 1.5 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus LRR_8 PF13855.6 KFM80082.1 - 1.2e-14 53.8 8.6 3.1e-11 42.9 3.9 3.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM80082.1 - 2.4e-07 30.9 11.0 6e-06 26.5 6.1 3.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM80082.1 - 3.6e-07 29.8 3.5 2.5e-05 23.8 2.3 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFM80082.1 - 6e-05 23.0 11.0 0.67 10.7 0.7 5.3 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_5 PF13306.6 KFM80082.1 - 0.0083 16.1 1.3 0.025 14.6 0.0 2.3 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFM80082.1 - 0.031 14.3 6.6 1.6 9.0 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich repeat SDA1 PF05285.12 KFM80083.1 - 1.8e-72 244.7 61.1 3.5e-72 243.7 51.0 2.9 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KFM80083.1 - 7.4e-20 71.0 0.4 3.1e-19 69.0 0.1 2.4 2 0 0 2 2 2 1 NUC130/3NT domain Peptidase_C2 PF00648.21 KFM80085.1 - 7.9e-76 254.9 0.0 9.8e-76 254.6 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease HECA PF15353.6 KFM80085.1 - 0.098 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Headcase protein family homologue zf-RanBP PF00641.18 KFM80086.1 - 6.2e-17 60.6 32.0 7.5e-08 31.6 3.4 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 KFM80086.1 - 0.00031 20.7 19.3 0.047 13.7 11.7 3.3 2 1 1 3 3 3 3 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KFM80086.1 - 0.18 11.8 13.2 3.8 7.6 0.2 4.6 5 0 0 5 5 5 0 Transposase zinc-ribbon domain HypA PF01155.19 KFM80086.1 - 2.1 8.4 16.5 0.86 9.6 1.0 3.3 3 1 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RanBP PF00641.18 KFM80087.1 - 0.0058 15.9 2.9 0.0058 15.9 2.9 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RecR PF02132.15 KFM80087.1 - 0.15 11.6 4.4 0.29 10.8 4.4 1.4 1 0 0 1 1 1 0 RecR protein Rubredoxin_2 PF18073.1 KFM80087.1 - 0.33 10.7 4.2 0.38 10.5 0.6 2.2 1 1 1 2 2 2 0 Rubredoxin metal binding domain PH PF00169.29 KFM80088.1 - 0.00014 22.3 0.0 0.00016 22.1 0.0 1.0 1 0 0 1 1 1 1 PH domain CBM_14 PF01607.24 KFM80090.1 - 5.6e-23 80.8 21.4 1.6e-10 40.9 3.4 3.5 3 1 0 3 3 3 3 Chitin binding Peritrophin-A domain Baculo_VP91_N PF08475.10 KFM80090.1 - 0.036 13.8 6.0 1.5 8.5 0.0 2.8 2 1 1 3 3 3 0 Viral capsid protein 91 N-terminal zf-C2H2 PF00096.26 KFM80091.1 - 5.5e-07 29.7 8.9 0.00053 20.3 4.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM80091.1 - 4.7e-05 23.6 5.5 6.8e-05 23.1 0.8 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM80091.1 - 0.056 14.3 8.1 0.24 12.4 3.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KFM80091.1 - 1.2 9.9 4.6 4.7 7.9 0.2 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain Metallophos_2 PF12850.7 KFM80092.1 - 5.2e-22 78.8 0.1 6.1e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFM80092.1 - 3.1e-05 24.6 1.0 0.0097 16.4 1.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HMG_CoA_synt_C PF08540.10 KFM80093.1 - 1.2e-102 343.3 2.7 1.8e-102 342.8 2.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFM80093.1 - 8.1e-97 322.1 0.3 1.3e-96 321.4 0.3 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal zf-H2C2_5 PF13909.6 KFM80096.1 - 1.9e-08 33.9 2.1 4.2e-08 32.8 2.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM80096.1 - 0.095 13.6 2.7 0.13 13.1 0.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Git3 PF11710.8 KFM80096.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 zf-C2H2 PF00096.26 KFM80097.1 - 0.00016 21.9 3.9 0.0002 21.7 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80097.1 - 0.0013 19.4 2.2 0.0016 19.1 2.2 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM80097.1 - 0.0019 18.6 0.0 0.0019 18.6 0.0 1.9 2 1 0 2 2 2 1 Zinc-finger double domain IF4E PF01652.18 KFM80098.1 - 6.1e-56 188.6 1.6 7.2e-56 188.4 1.6 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Crust_neurohorm PF01147.17 KFM80099.1 - 3.7e-16 58.7 0.9 4.8e-16 58.3 0.9 1.2 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family zf-UBR PF02207.20 KFM80099.1 - 0.047 13.9 1.4 0.07 13.3 1.4 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Ribosomal_L36 PF00444.18 KFM80099.1 - 0.16 12.2 1.2 0.28 11.4 1.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L36 DUF4396 PF14342.6 KFM80100.1 - 0.021 15.2 0.2 0.03 14.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) Sigma_reg_N PF13800.6 KFM80100.1 - 0.18 12.1 0.6 2.7 8.4 0.2 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal 7tm_2 PF00002.24 KFM80101.1 - 4.1e-44 150.7 9.9 5.6e-44 150.3 9.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KFM80101.1 - 0.048 12.8 8.8 0.064 12.4 8.8 1.1 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor RRM_1 PF00076.22 KFM80104.1 - 8.6e-05 22.3 0.0 0.00014 21.6 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM80104.1 - 0.0071 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_AraC PF00165.23 KFM80104.1 - 0.18 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family TMEM219 PF14940.6 KFM80107.1 - 0.065 12.8 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 Transmembrane 219 Kinesin PF00225.23 KFM80108.1 - 5.4e-115 383.9 0.3 5.4e-115 383.9 0.3 1.6 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 KFM80108.1 - 6.2e-56 189.4 16.4 3.2e-49 167.5 1.1 3.4 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 KFM80108.1 - 1.1e-21 77.4 0.1 1.1e-21 77.4 0.1 3.2 3 0 0 3 3 3 1 Microtubule binding KIF1B PF12423.8 KFM80108.1 - 2.7e-14 53.3 4.8 8.8e-12 45.3 0.0 3.6 3 0 0 3 3 3 2 Kinesin protein 1B DUF3694 PF12473.8 KFM80108.1 - 9.8e-09 36.0 0.0 2.6e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein FHA PF00498.26 KFM80108.1 - 0.00022 21.5 0.1 0.0015 18.8 0.0 2.4 2 0 0 2 2 2 1 FHA domain Zeta_toxin PF06414.12 KFM80108.1 - 0.03 13.6 0.2 0.094 12.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin YlqD PF11068.8 KFM80108.1 - 9.8 6.6 21.2 13 6.2 4.6 2.5 2 0 0 2 2 2 0 YlqD protein Atg8 PF02991.16 KFM80112.1 - 0.018 15.2 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like AAA PF00004.29 KFM80114.1 - 3.5e-59 199.0 0.0 2e-43 148.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KFM80114.1 - 1.4e-16 60.7 1.3 6.8e-16 58.5 1.3 2.3 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KFM80114.1 - 1.1e-14 54.0 0.0 1e-09 38.0 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KFM80114.1 - 2.3e-09 37.9 0.3 0.064 13.6 0.0 4.4 3 2 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 KFM80114.1 - 3e-08 34.0 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KFM80114.1 - 4.2e-08 33.1 0.0 0.0041 16.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KFM80114.1 - 4.6e-07 30.2 0.1 0.018 15.4 0.0 4.0 4 0 0 4 4 3 2 RNA helicase RuvB_N PF05496.12 KFM80114.1 - 4.9e-07 29.6 0.0 0.00073 19.3 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFM80114.1 - 7.2e-07 29.3 0.3 0.085 12.9 0.1 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFM80114.1 - 8.6e-07 29.6 0.0 0.076 13.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFM80114.1 - 1.3e-06 28.6 0.0 0.012 15.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM80114.1 - 1.4e-06 28.6 0.6 0.058 13.7 0.0 3.6 2 1 0 3 3 3 2 AAA domain PEX-2N PF09263.10 KFM80114.1 - 7.7e-06 26.1 1.4 2.6e-05 24.5 1.4 2.0 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal Mg_chelatase PF01078.21 KFM80114.1 - 2.5e-05 23.8 0.2 0.24 10.7 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KFM80114.1 - 3.1e-05 24.0 0.0 0.3 11.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KFM80114.1 - 4.6e-05 23.0 0.1 0.42 10.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 KFM80114.1 - 0.00012 22.1 0.0 0.018 15.0 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 KFM80114.1 - 0.00024 20.4 0.1 0.058 12.6 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain ABC_tran PF00005.27 KFM80114.1 - 0.00041 20.9 0.1 0.53 10.8 0.0 3.1 3 0 0 3 3 2 1 ABC transporter AAA_28 PF13521.6 KFM80114.1 - 0.00043 20.6 0.1 0.91 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFM80114.1 - 0.00044 19.9 0.0 0.078 12.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KFM80114.1 - 0.00073 19.3 0.2 1.1 9.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 KFM80114.1 - 0.00087 19.2 0.2 0.05 13.6 0.1 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 KFM80114.1 - 0.00096 19.2 0.0 0.56 10.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFM80114.1 - 0.0013 18.3 2.4 0.35 10.4 0.0 3.1 2 1 0 3 3 3 1 AAA domain T2SSE PF00437.20 KFM80114.1 - 0.0022 17.1 0.1 0.56 9.2 0.0 2.6 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 KFM80114.1 - 0.0035 17.7 0.3 2.8 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KFM80114.1 - 0.0041 16.9 0.1 0.87 9.3 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 KFM80114.1 - 0.0041 17.1 0.7 8.4 6.3 0.0 3.5 3 0 0 3 3 3 0 NACHT domain NTPase_1 PF03266.15 KFM80114.1 - 0.0049 16.8 2.2 0.41 10.6 0.1 3.3 3 0 0 3 3 3 1 NTPase SRP54 PF00448.22 KFM80114.1 - 0.0085 15.7 1.3 0.082 12.5 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Parvo_NS1 PF01057.17 KFM80114.1 - 0.0096 15.0 0.1 1.2 8.2 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KFM80114.1 - 0.012 14.8 0.0 4.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KFM80114.1 - 0.013 15.5 0.8 1.2 9.0 0.0 3.4 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFM80114.1 - 0.017 14.3 0.0 6.7 5.8 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.15 KFM80114.1 - 0.03 14.3 0.5 1.6 8.7 0.1 2.9 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Roc PF08477.13 KFM80114.1 - 0.033 14.4 0.2 0.37 11.0 0.0 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KFM80114.1 - 0.044 14.3 0.0 0.044 14.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.11 KFM80114.1 - 0.047 13.6 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KFM80114.1 - 0.048 12.9 0.1 2.7 7.2 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 KFM80114.1 - 0.054 13.6 0.0 2.2 8.4 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 KFM80114.1 - 0.064 13.0 0.1 9.1 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KFM80114.1 - 0.089 12.2 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DNA_ligase_OB PF03120.16 KFM80114.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain MCM PF00493.23 KFM80114.1 - 0.11 11.6 0.1 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain PduV-EutP PF10662.9 KFM80114.1 - 0.12 12.1 0.5 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 KFM80114.1 - 0.14 11.4 0.7 0.58 9.5 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 KFM80114.1 - 0.23 11.9 0.8 6.2 7.2 0.1 2.9 2 0 0 2 2 2 0 AAA domain YvbH_ext PF11724.8 KFM80115.1 - 0.084 13.2 0.3 0.18 12.2 0.0 1.7 2 0 0 2 2 2 0 YvbH-like oligomerisation region SelP_N PF04592.14 KFM80115.1 - 0.55 9.6 21.9 0.8 9.1 21.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 KFM80115.1 - 0.66 9.1 5.8 0.82 8.8 5.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Conotoxin PF02950.17 KFM80116.1 - 0.056 14.5 1.8 0.33 12.0 1.8 2.2 1 1 0 1 1 1 0 Conotoxin RhoGAP PF00620.27 KFM80117.1 - 1.1e-45 155.2 0.0 3.3e-45 153.6 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain SH3_2 PF07653.17 KFM80117.1 - 0.059 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_9 PF14604.6 KFM80117.1 - 0.12 12.3 0.1 0.38 10.7 0.1 1.9 1 0 0 1 1 1 0 Variant SH3 domain PX PF00787.24 KFM80118.1 - 4.4e-08 33.1 0.3 6.3e-08 32.6 0.3 1.2 1 0 0 1 1 1 1 PX domain CRAL_TRIO PF00650.20 KFM80119.1 - 1.3e-33 116.0 0.0 2.8e-33 114.9 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM80119.1 - 2.1e-06 27.8 0.1 6.6e-06 26.2 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain GOLD_2 PF13897.6 KFM80119.1 - 4.4e-06 27.2 0.0 0.0029 18.1 0.0 2.4 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.6 KFM80119.1 - 0.00014 22.1 0.0 0.00025 21.2 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain C1q PF00386.21 KFM80119.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 C1q domain A2M_BRD PF07703.14 KFM80120.1 - 8.8e-30 103.9 2.7 1.9e-28 99.6 1.2 3.0 3 0 0 3 3 3 1 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 KFM80120.1 - 1.4e-18 66.9 0.0 8.1e-18 64.5 0.0 2.4 3 0 0 3 3 3 1 Macroglobulin domain MG3 MG2 PF01835.19 KFM80120.1 - 5.8e-16 58.7 0.0 5.5e-15 55.6 0.0 2.6 3 0 0 3 3 3 1 MG2 domain MG4 PF17789.1 KFM80120.1 - 8.6e-13 48.3 0.0 2.7e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG4 Lamp PF01299.17 KFM80120.1 - 0.027 14.3 0.1 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) DUF585 PF04522.12 KFM80120.1 - 0.055 13.1 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF585) zf-C2H2_4 PF13894.6 KFM80121.1 - 0.0027 18.4 36.3 0.2 12.6 2.4 6.7 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.7 KFM80121.1 - 0.0039 17.5 16.8 0.17 12.3 1.0 5.9 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFM80121.1 - 0.82 10.3 34.3 0.24 11.9 1.8 6.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KFM80121.1 - 2.9 8.0 11.5 1.3 9.2 0.5 3.5 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFM80121.1 - 2.9 8.0 18.1 0.13 12.3 1.2 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger Zf_RING PF16744.5 KFM80121.1 - 3.8 7.7 7.3 3.9 7.7 0.8 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger DDE_Tnp_IS1595 PF12762.7 KFM80122.1 - 1.3e-19 70.7 0.0 1.8e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KFM80122.1 - 0.033 13.7 0.0 0.045 13.2 0.0 1.4 1 1 0 1 1 1 0 Transposase IS66 family DDE_3 PF13358.6 KFM80122.1 - 0.11 12.2 0.0 0.48 10.2 0.0 2.0 1 1 0 1 1 1 0 DDE superfamily endonuclease TetR_C_30 PF17939.1 KFM80122.1 - 0.12 12.7 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain 7tm_1 PF00001.21 KFM80123.1 - 8.4e-10 38.4 0.6 2.1e-09 37.1 0.2 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Pox_EPC_I2-L1 PF12575.8 KFM80123.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF971 PF06155.12 KFM80124.1 - 0.12 13.0 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Iso_dh PF00180.20 KFM80125.1 - 2.1e-75 254.0 0.0 2.6e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Bromo_TP PF07524.13 KFM80126.1 - 2.8e-07 30.4 0.2 3.2e-07 30.3 0.2 1.1 1 0 0 1 1 1 1 Bromodomain associated SVWC PF15430.6 KFM80127.1 - 5.8e-09 36.1 6.8 5.8e-09 36.1 6.8 1.6 2 0 0 2 2 2 1 Single domain von Willebrand factor type C BACK PF07707.15 KFM80132.1 - 7.8e-07 29.1 1.3 2.4e-06 27.6 0.5 2.2 1 1 1 2 2 2 1 BTB And C-terminal Kelch DUF3826 PF12875.7 KFM80133.1 - 0.071 13.2 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) Mucin PF01456.17 KFM80137.1 - 6.2 6.8 28.5 3.5 7.6 26.6 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein AMP-binding PF00501.28 KFM80138.1 - 4e-50 170.6 0.0 5.3e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM80138.1 - 9.2e-08 31.9 5.4 1.7e-07 31.0 5.4 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Rho_RNA_bind PF07497.12 KFM80138.1 - 0.16 11.9 0.0 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain AMP-binding PF00501.28 KFM80139.1 - 4.1e-37 127.8 0.0 5.4e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Endothelin PF00322.17 KFM80140.1 - 3.9 7.2 6.0 5.2 6.8 0.4 3.0 3 0 0 3 3 3 0 Endothelin family AMP-binding_C PF13193.6 KFM80141.1 - 0.0072 17.3 0.0 0.017 16.1 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFM80142.1 - 1.7e-27 96.1 0.0 2.1e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KFM80143.1 - 8.6e-42 143.2 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM80143.1 - 3e-09 36.6 6.0 5.6e-09 35.8 6.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus RNase_T PF00929.24 KFM80145.1 - 3e-17 63.6 0.0 1.4e-16 61.5 0.0 2.1 2 0 0 2 2 2 1 Exonuclease APS_kinase PF01583.20 KFM80147.1 - 1.4e-71 239.5 0.0 2.6e-71 238.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KFM80147.1 - 1.7e-65 220.5 0.0 2.2e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KFM80147.1 - 2.1e-49 167.2 0.0 3.4e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 KFM80147.1 - 4.5e-06 26.9 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM80147.1 - 0.022 15.3 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF5613 PF18467.1 KFM80147.1 - 0.055 13.9 0.0 1.8 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5613) RsgA_GTPase PF03193.16 KFM80147.1 - 0.2 11.6 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase PEPCK_ATP PF01293.20 KFM80147.1 - 0.28 9.8 0.2 0.48 9.0 0.2 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase PRE_C2HC PF07530.11 KFM80148.1 - 4.7e-11 42.6 0.1 1.2e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 Associated with zinc fingers DHHA1 PF02272.19 KFM80149.1 - 5.2e-22 78.7 1.2 5.9e-22 78.6 1.2 1.0 1 0 0 1 1 1 1 DHHA1 domain DSPc PF00782.20 KFM80152.1 - 1.6e-13 50.6 0.4 2e-13 50.3 0.4 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM80152.1 - 5.8e-07 29.3 0.8 6.6e-07 29.1 0.8 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KFM80152.1 - 0.0036 17.0 0.2 0.0052 16.5 0.2 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KFM80152.1 - 0.0048 16.9 0.2 0.0059 16.6 0.2 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM80152.1 - 0.22 11.7 0.5 0.41 10.8 0.1 1.6 1 1 1 2 2 2 0 Inositol hexakisphosphate PhyH PF05721.13 KFM80155.1 - 1.3e-42 146.5 0.0 1.6e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RFX_DNA_binding PF02257.15 KFM80157.1 - 1.5e-13 51.2 0.1 2.8e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain FOXP-CC PF16159.5 KFM80157.1 - 0.11 13.1 7.8 1.6 9.4 3.0 3.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KFM80157.1 - 1 9.9 2.7 1.1 9.8 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DcpS_C PF11969.8 KFM80159.1 - 4.1e-28 98.1 0.5 4.8e-28 97.9 0.5 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KFM80159.1 - 1.8e-11 44.6 4.0 5e-11 43.2 4.0 1.7 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 KFM80159.1 - 0.007 16.2 2.2 0.012 15.5 2.2 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RNA_pol_Rpc4 PF05132.14 KFM80160.1 - 4.6e-09 36.9 2.4 4.6e-09 36.9 2.4 2.8 3 1 0 3 3 3 1 RNA polymerase III RPC4 FXMRP1_C_core PF12235.8 KFM80160.1 - 0.23 12.1 0.2 0.23 12.1 0.2 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal APC1_C PF18122.1 KFM80161.1 - 1.1e-14 54.7 0.2 2.3e-14 53.7 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 KFM80161.1 - 0.011 16.2 18.9 9.7 6.8 0.2 6.3 6 0 0 6 6 6 0 Proteasome/cyclosome repeat ANAPC1 PF12859.7 KFM80163.1 - 0.67 10.5 0.1 0.67 10.5 0.1 3.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 MFS_1_like PF12832.7 KFM80165.1 - 3.1e-78 263.3 15.3 3.8e-78 263.0 15.3 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM80165.1 - 7e-16 58.1 35.8 9.1e-10 38.0 22.9 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFM80165.1 - 1.7e-15 56.9 15.3 1.4e-13 50.6 13.9 2.0 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 KFM80165.1 - 3.9e-09 35.8 18.8 0.00035 19.5 0.8 2.8 2 1 0 2 2 2 2 LacY proton/sugar symporter MFS_2 PF13347.6 KFM80165.1 - 7.9e-07 28.0 22.7 0.002 16.8 15.8 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFM80166.1 - 4e-16 58.9 1.4 5.4e-16 58.4 0.7 1.5 1 1 1 2 2 2 1 MFS_1 like family Nuc_H_symport PF03825.16 KFM80166.1 - 1.9e-08 33.7 0.1 2.4e-08 33.4 0.1 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1 PF07690.16 KFM80166.1 - 5.4e-06 25.6 1.8 8.1e-06 25.0 1.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM80166.1 - 4.3e-05 22.6 0.2 6.1e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter BT1 PF03092.16 KFM80166.1 - 0.047 11.9 0.2 0.25 9.5 0.1 1.7 1 1 1 2 2 2 0 BT1 family MFS_1_like PF12832.7 KFM80167.1 - 4.9e-14 52.0 0.0 5.2e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 KFM80167.1 - 0.00056 19.0 0.1 0.00079 18.5 0.1 1.2 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1_like PF12832.7 KFM80168.1 - 6.1e-77 259.1 18.5 7.2e-77 258.8 18.5 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM80168.1 - 4.3e-08 32.5 40.6 1.4e-05 24.3 0.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 KFM80168.1 - 1.9e-07 30.2 20.8 2.6e-05 23.2 0.3 2.7 2 1 1 3 3 3 2 LacY proton/sugar symporter ANAPC10 PF03256.16 KFM80169.1 - 1.8e-07 31.0 0.1 3.3e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) zf-RING_2 PF13639.6 KFM80169.1 - 3.4e-05 24.1 10.2 3.4e-05 24.1 10.2 5.8 4 2 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.7 KFM80169.1 - 0.0029 17.9 6.7 0.0029 17.9 6.7 4.6 4 0 0 4 4 4 1 RING-H2 zinc finger domain SH3_3 PF08239.11 KFM80170.1 - 2.4e-14 53.3 0.0 5.5e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 Bacterial SH3 domain Filamin PF00630.19 KFM80170.1 - 1.1e-06 29.3 0.0 4.7e-06 27.3 0.0 2.1 1 0 0 1 1 1 1 Filamin/ABP280 repeat CelD_N PF02927.14 KFM80170.1 - 0.032 15.1 0.0 0.1 13.5 0.0 1.9 1 0 0 1 1 1 0 Cellulase N-terminal ig-like domain PHR PF08005.12 KFM80171.1 - 2.7e-44 151.5 0.0 4e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 PHR domain RCC1 PF00415.18 KFM80172.1 - 1.2e-29 102.6 10.8 7.9e-12 45.6 0.1 8.3 9 0 0 9 9 9 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM80172.1 - 2.8e-21 74.8 19.7 3.8e-07 29.7 0.3 5.9 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat MamL-1 PF09596.10 KFM80172.1 - 0.11 12.8 5.4 0.25 11.6 5.4 1.6 1 0 0 1 1 1 0 MamL-1 domain Nuc_deoxyri_tr3 PF11071.8 KFM80173.1 - 0.042 13.9 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ HSP90 PF00183.18 KFM80174.1 - 4.7e-100 335.9 8.2 6.9e-96 322.2 5.1 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 KFM80174.1 - 4.7e-11 42.7 0.1 1.5e-10 41.1 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFM80174.1 - 3.3e-07 30.8 0.1 6.1e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SpoVIF PF14069.6 KFM80174.1 - 0.15 11.9 2.2 7.4 6.4 0.0 4.1 5 0 0 5 5 5 0 Stage VI sporulation protein F DUF3805 PF12712.7 KFM80175.1 - 0.0026 17.9 0.6 0.0046 17.1 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3805) Mpp10 PF04006.12 KFM80180.1 - 2.6e-139 465.5 65.3 3.1e-139 465.3 65.3 1.0 1 0 0 1 1 1 1 Mpp10 protein B12D PF06522.11 KFM80181.1 - 0.0004 20.1 0.0 0.00048 19.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Tubulin PF00091.25 KFM80182.1 - 5.7e-09 36.5 0.0 6e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Peptidase_M10 PF00413.24 KFM80184.1 - 2.4e-54 183.4 0.0 4.3e-54 182.6 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFM80184.1 - 1.3e-43 146.7 15.6 3e-12 46.3 0.1 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFM80184.1 - 5.4e-13 48.9 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_4 PF13583.6 KFM80184.1 - 0.023 14.4 0.1 0.06 13.0 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFM80184.1 - 0.042 13.0 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 KFM80184.1 - 0.043 14.3 0.2 0.092 13.3 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KFM80184.1 - 0.19 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Astacin PF01400.24 KFM80184.1 - 0.2 11.3 0.5 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) DEAD PF00270.29 KFM80186.1 - 2.4e-17 63.2 0.0 5e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM80186.1 - 1.4e-13 51.1 0.0 5.2e-11 42.9 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KFM80186.1 - 1.6e-09 38.3 8.7 3.2e-09 37.4 4.5 3.5 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 KFM80186.1 - 4.7e-05 23.5 0.0 0.00023 21.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFM80186.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain KIX_2 PF16987.5 KFM80186.1 - 0.052 13.6 0.1 0.2 11.7 0.1 2.0 1 0 0 1 1 1 0 KIX domain EB PF01683.18 KFM80187.1 - 1.3e-12 47.8 30.7 1.6e-06 28.3 3.4 3.4 1 1 2 3 3 3 3 EB module Exo70 PF03081.15 KFM80188.1 - 3.2e-81 273.3 9.1 5.1e-81 272.6 9.1 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Vps52 PF04129.12 KFM80189.1 - 0.0072 15.1 0.9 0.008 15.0 0.9 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family DUF4201 PF13870.6 KFM80189.1 - 0.018 14.8 0.7 0.022 14.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4795 PF16043.5 KFM80189.1 - 0.03 13.9 0.5 0.033 13.8 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) COG5 PF10392.9 KFM80189.1 - 0.031 14.5 0.8 0.036 14.2 0.8 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Sec3_C PF09763.9 KFM80189.1 - 0.056 11.8 2.2 0.066 11.6 2.2 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 AMP-binding PF00501.28 KFM80190.1 - 2.3e-106 355.9 0.0 3e-106 355.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM80190.1 - 0.00072 20.5 0.0 0.0022 18.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_8 PF13855.6 KFM80191.1 - 2.1e-16 59.4 5.1 2.7e-11 43.1 0.9 2.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM80191.1 - 1.3e-13 50.8 7.1 7.8e-08 32.5 1.4 3.4 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM80191.1 - 8.2e-07 28.7 8.6 2.9 8.8 0.2 5.8 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 KFM80191.1 - 0.00032 20.5 10.1 2.2 8.6 0.1 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 KFM80191.1 - 0.015 14.8 3.1 0.32 10.5 0.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeat Sec23_helical PF04815.15 KFM80191.1 - 0.022 14.6 0.2 0.085 12.7 0.0 1.9 2 0 0 2 2 2 0 Sec23/Sec24 helical domain MCU PF04678.13 KFM80192.1 - 2.4e-39 135.2 3.7 3e-39 134.9 3.7 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter PID PF00640.23 KFM80194.1 - 2e-09 37.6 0.0 2.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KFM80195.1 - 7.7e-15 54.8 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 SH2 domain DDE_3 PF13358.6 KFM80196.1 - 0.0001 22.0 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_3 PF07720.12 KFM80196.1 - 0.036 14.1 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1180 PF06679.12 KFM80197.1 - 1.7e-23 83.9 0.0 2.1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) SID-1_RNA_chan PF13965.6 KFM80197.1 - 0.014 13.9 0.2 0.045 12.2 0.1 1.7 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 DUF3985 PF13153.6 KFM80197.1 - 0.074 13.1 0.3 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3985) Peptidase_S46 PF10459.9 KFM80198.1 - 0.026 13.2 0.5 0.028 13.1 0.5 1.0 1 0 0 1 1 1 0 Peptidase S46 LRR_8 PF13855.6 KFM80199.1 - 4e-12 45.7 20.4 7.6e-08 32.0 4.0 3.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KFM80199.1 - 0.0019 18.1 2.0 3.6 7.9 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.7 KFM80199.1 - 0.11 12.9 0.5 0.11 12.9 0.5 3.5 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) RSS_P20 PF11757.8 KFM80199.1 - 0.21 12.1 0.5 0.41 11.1 0.5 1.5 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain LRR_1 PF00560.33 KFM80199.1 - 5.8 7.9 9.0 67 4.6 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Trypsin PF00089.26 KFM80200.1 - 4.3e-16 59.4 0.1 5.4e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 KFM80200.1 - 2.5e-07 30.8 13.9 5.5e-07 29.7 13.9 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 KFM80200.1 - 0.13 12.7 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFM80201.1 - 0.0013 18.6 0.2 0.0015 18.4 0.2 1.1 1 0 0 1 1 1 1 Trypsin ubiquitin PF00240.23 KFM80202.1 - 8.7e-14 51.0 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBD PF16455.5 KFM80202.1 - 2.4e-07 30.9 0.1 4.2e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-binding domain Rad60-SLD PF11976.8 KFM80202.1 - 0.00012 21.8 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Arginase PF00491.21 KFM80203.1 - 1.1e-89 300.7 0.0 1.4e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family CREPT PF16566.5 KFM80205.1 - 0.00018 21.7 2.8 0.00018 21.7 2.8 4.5 1 1 2 4 4 2 1 Cell-cycle alteration and expression-elevated protein in tumour APG6_N PF17675.1 KFM80205.1 - 0.00041 20.9 73.8 0.0011 19.5 25.5 3.8 1 1 2 3 3 3 1 Apg6 coiled-coil region Cnn_1N PF07989.11 KFM80205.1 - 0.011 15.8 2.8 0.011 15.8 2.8 6.5 3 2 4 7 7 6 0 Centrosomin N-terminal motif 1 Strep_SA_rep PF06696.11 KFM80205.1 - 0.017 15.1 2.7 0.42 10.7 0.0 3.7 3 0 0 3 3 3 0 Streptococcal surface antigen repeat AAA_13 PF13166.6 KFM80205.1 - 0.02 13.6 43.8 0.28 9.8 27.2 2.2 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.11 KFM80205.1 - 0.058 12.3 66.5 0.3 9.9 14.9 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Filament PF00038.21 KFM80205.1 - 1.5 8.3 60.5 1.2 8.6 6.6 3.9 1 1 0 2 2 2 0 Intermediate filament protein ApoO PF09769.9 KFM80205.1 - 2.1 8.3 17.6 0.86 9.6 3.5 4.2 2 1 2 4 4 4 0 Apolipoprotein O IFT57 PF10498.9 KFM80205.1 - 3 6.7 49.3 0.014 14.4 3.6 3.6 2 1 2 4 4 4 0 Intra-flagellar transport protein 57 DASH_Dam1 PF08653.10 KFM80205.1 - 3.1 7.7 18.8 1 9.2 1.0 5.7 6 0 0 6 6 6 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 KFM80205.1 - 3.5 7.8 53.8 0.056 13.6 8.2 5.2 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family MAP65_ASE1 PF03999.12 KFM80205.1 - 4.5 5.9 52.5 0.98 8.0 47.5 1.9 1 1 1 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) DUF3584 PF12128.8 KFM80205.1 - 8.2 3.8 60.5 28 2.0 59.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Kinesin PF00225.23 KFM80206.1 - 4.1e-100 335.0 1.9 4.1e-100 335.0 1.9 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFM80206.1 - 3.9e-16 59.3 2.8 6.4e-16 58.6 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding HEPN_AbiA_CTD PF18732.1 KFM80206.1 - 0.43 10.5 3.6 0.56 10.2 0.2 2.5 2 1 0 2 2 2 0 HEPN like, Abia C-terminal domain DUF724 PF05266.14 KFM80206.1 - 0.44 10.3 19.2 0.097 12.5 10.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF948 PF06103.11 KFM80206.1 - 3 8.2 4.4 5 7.5 2.7 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 KFM80206.1 - 7 7.3 15.3 2.8 8.6 9.8 2.8 2 1 0 2 2 2 0 SlyX zf-CXXC PF02008.20 KFM80208.1 - 1e-05 25.4 21.6 2.7e-05 24.1 21.6 1.7 1 0 0 1 1 1 1 CXXC zinc finger domain Tet_JBP PF12851.7 KFM80209.1 - 7e-16 58.5 0.3 8.9e-16 58.1 0.3 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HoxA13_N PF12284.8 KFM80209.1 - 0.017 15.7 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 Hox protein A13 N terminal Tet_JBP PF12851.7 KFM80210.1 - 2.8e-44 151.8 26.4 6.4e-42 144.1 26.4 2.4 1 1 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Pyr_redox_2 PF07992.14 KFM80211.1 - 3.9e-11 42.7 0.0 7.5e-10 38.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM80211.1 - 0.0055 16.0 1.1 2.2 7.4 0.2 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM80211.1 - 0.012 16.1 0.0 0.078 13.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFM80211.1 - 0.013 15.5 0.0 1.9 8.5 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Tox-PL-2 PF15643.6 KFM80211.1 - 0.097 12.8 0.1 2.2 8.5 0.0 2.7 3 0 0 3 3 3 0 Papain fold toxin 2 TBP PF00352.21 KFM80212.1 - 1.5e-39 133.8 0.1 1.8e-33 114.3 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFM80212.1 - 0.096 12.8 0.6 0.82 9.8 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3378) Auxin_repressed PF05564.12 KFM80212.1 - 1.6 9.4 4.3 8.5 7.1 4.3 2.0 1 1 0 1 1 1 0 Dormancy/auxin associated protein TBP PF00352.21 KFM80213.1 - 9.9e-13 47.9 0.0 1e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) Sulfotransfer_1 PF00685.27 KFM80214.1 - 5e-77 259.0 0.2 6.5e-77 258.6 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM80214.1 - 1.5e-08 35.3 0.0 6.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family CDP-OH_P_transf PF01066.21 KFM80215.1 - 1.5e-11 44.8 0.6 1.5e-11 44.8 0.6 2.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Plasmod_dom_1 PF09715.10 KFM80215.1 - 0.13 12.4 1.1 2.2 8.4 0.0 2.8 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF1977 PF09320.11 KFM80216.1 - 6.2e-29 100.4 0.1 2.3e-28 98.5 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KFM80216.1 - 2e-26 91.9 0.1 4.4e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain ArnB_C PF18677.1 KFM80216.1 - 0.025 14.7 0.1 0.1 12.7 0.1 2.0 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain TMEM154 PF15102.6 KFM80216.1 - 0.2 11.6 0.0 0.96 9.3 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family Pkinase_Tyr PF07714.17 KFM80217.1 - 1e-96 323.2 0.0 1.4e-96 322.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM80217.1 - 3.4e-49 167.6 0.0 5e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cadherin PF00028.17 KFM80217.1 - 0.0001 22.7 0.0 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 Cadherin domain APH PF01636.23 KFM80217.1 - 0.00037 20.5 0.0 0.16 11.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM80217.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KFM80217.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-C2H2 PF00096.26 KFM80218.1 - 0.053 14.0 2.2 0.053 14.0 2.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80218.1 - 0.16 12.9 3.1 0.22 12.4 0.9 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger RGM_N PF06535.12 KFM80219.1 - 8.4e-52 175.7 0.8 1.4e-51 174.9 0.8 1.4 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus RGM_C PF06534.13 KFM80219.1 - 2e-44 151.2 0.3 7e-44 149.4 0.3 1.9 1 1 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus DUF1077 PF06417.12 KFM80220.1 - 8.3e-45 151.6 2.2 1e-44 151.3 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Sas10_Utp3 PF04000.15 KFM80221.1 - 2.9e-18 66.3 0.4 8.9e-18 64.7 0.4 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Zona_pellucida PF00100.23 KFM80223.1 - 9.6e-11 42.0 0.0 1.3e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain BCIP PF13862.6 KFM80224.1 - 2.7e-23 82.8 0.4 4e-23 82.3 0.4 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Thiol_cytolysin PF01289.19 KFM80224.1 - 0.036 13.0 0.0 0.043 12.7 0.0 1.0 1 0 0 1 1 1 0 Thiol-activated cytolysin Ras PF00071.22 KFM80225.1 - 1.6e-56 190.4 0.3 1.9e-56 190.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM80225.1 - 8e-22 77.7 0.0 1.3e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM80225.1 - 7.8e-10 38.5 0.1 8.9e-10 38.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM80225.1 - 9.8e-06 25.2 0.7 2.3e-05 24.0 0.2 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM80225.1 - 5.6e-05 23.2 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KFM80225.1 - 0.00036 19.8 0.9 0.08 12.1 0.4 2.1 1 1 1 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 KFM80225.1 - 0.014 15.3 2.2 2.4 8.0 0.7 2.3 1 1 0 2 2 2 0 RsgA GTPase EMC3_TMCO1 PF01956.16 KFM80226.1 - 0.78 9.5 2.9 0.8 9.4 2.9 1.0 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like zf-MIZ PF02891.20 KFM80227.1 - 2.8e-23 81.4 4.0 2.8e-23 81.4 4.0 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFM80227.1 - 1.4e-05 24.8 1.0 1.4e-05 24.8 1.0 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Zmiz1_N PF18028.1 KFM80228.1 - 1e-07 32.2 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Zmiz1 N-terminal tetratricopeptide repeat domain INSIG PF07281.12 KFM80230.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Methyltransf_25 PF13649.6 KFM80232.1 - 5.1e-15 56.0 0.0 8.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM80232.1 - 6.8e-13 49.1 0.0 1e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 KFM80232.1 - 1.2e-10 41.3 0.0 2e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_31 PF13847.6 KFM80232.1 - 1.6e-10 41.0 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM80232.1 - 1.8e-09 37.6 0.0 2.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KFM80232.1 - 5.3e-09 36.0 0.0 7.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 KFM80232.1 - 1.9e-08 33.9 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 KFM80232.1 - 8.9e-08 32.8 0.0 1.6e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KFM80232.1 - 4.8e-05 22.6 0.0 6.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KFM80232.1 - 8.7e-05 21.9 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 KFM80232.1 - 0.00095 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 KFM80232.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KFM80232.1 - 0.0026 17.2 0.0 0.0032 16.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KFM80232.1 - 0.0097 16.0 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Vma12 PF11712.8 KFM80234.1 - 0.0001 22.3 1.3 0.00016 21.8 1.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase IFP_35_N PF07334.13 KFM80234.1 - 0.0081 16.2 1.2 0.012 15.7 1.2 1.3 1 0 0 1 1 1 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus Methyltransf_10 PF05971.12 KFM80235.1 - 4.3e-73 246.3 0.0 6.7e-73 245.6 0.0 1.3 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KFM80235.1 - 6.5e-09 35.5 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFM80235.1 - 0.0053 16.2 0.4 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFM80235.1 - 0.01 16.5 0.1 0.074 13.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFM80235.1 - 0.01 16.5 0.1 3 8.6 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain SGS PF05002.15 KFM80236.1 - 3.2e-34 116.9 2.4 3.2e-34 116.9 2.4 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.16 KFM80236.1 - 3.4e-15 56.8 3.3 3.4e-15 56.8 1.7 1.9 2 0 0 2 2 2 1 CS domain CRS1_YhbY PF01985.21 KFM80236.1 - 0.056 13.6 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain Glyco_transf_24 PF18404.1 KFM80237.1 - 1.1e-147 490.6 3.7 2.1e-147 489.7 3.7 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KFM80237.1 - 5.6e-66 223.1 12.0 6e-61 206.6 0.3 4.3 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KFM80237.1 - 6.2e-54 183.1 3.6 3.7e-50 170.8 0.6 3.7 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFM80237.1 - 5.2e-47 160.2 3.0 9.4e-47 159.3 3.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFM80237.1 - 1.3e-39 134.7 0.0 5.3e-39 132.7 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KFM80237.1 - 1.6e-34 118.7 6.5 1.2e-33 115.9 2.5 3.4 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KFM80237.1 - 7.2e-05 22.5 0.5 0.00021 20.9 0.5 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 8 wnt PF00110.19 KFM80238.1 - 2.8e-36 125.7 15.3 2.9e-36 125.6 15.3 1.0 1 0 0 1 1 1 1 wnt family wnt PF00110.19 KFM80239.1 - 6.7e-35 121.2 0.1 7.2e-35 121.0 0.1 1.0 1 0 0 1 1 1 1 wnt family MG2 PF01835.19 KFM80242.1 - 1.9e-09 37.9 0.0 1.9e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 MG2 domain MG1 PF17790.1 KFM80242.1 - 0.0086 16.5 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 1 Macroglobulin domain MG1 OLF PF02191.16 KFM80242.1 - 0.056 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Olfactomedin-like domain A2M_BRD PF07703.14 KFM80242.1 - 0.18 12.2 0.0 5.2 7.4 0.0 2.6 1 1 1 3 3 3 0 Alpha-2-macroglobulin bait region domain LRR_12 PF18837.1 KFM80242.1 - 0.21 11.3 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat CUB PF00431.20 KFM80243.1 - 2.5e-20 72.9 0.0 2.7e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 CUB domain MFS_1 PF07690.16 KFM80247.1 - 1.1e-19 70.6 4.7 1.1e-13 50.9 0.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFM80247.1 - 0.015 14.3 0.1 0.015 14.3 0.1 1.9 2 0 0 2 2 2 0 Nucleoside H+ symporter Ferritin PF00210.24 KFM80249.1 - 5.2e-27 94.5 4.8 8.9e-27 93.8 4.8 1.4 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KFM80249.1 - 1.6e-05 25.4 2.7 3.3e-05 24.3 2.5 1.7 1 1 0 1 1 1 1 Rubrerythrin MA3 PF02847.17 KFM80249.1 - 0.018 15.0 0.1 0.046 13.7 0.1 1.7 1 0 0 1 1 1 0 MA3 domain Acid_PPase PF12689.7 KFM80249.1 - 0.062 13.1 0.1 0.18 11.7 0.1 1.6 1 1 0 1 1 1 0 Acid Phosphatase Peptidase_M10 PF00413.24 KFM80250.1 - 1.5e-35 122.4 0.0 2.8e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFM80250.1 - 1.5e-22 79.2 21.6 5.7e-07 29.4 0.1 4.9 4 1 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFM80250.1 - 8.9e-09 35.4 0.1 6.6e-08 32.7 0.0 2.3 2 1 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFM80250.1 - 0.00048 19.8 1.1 0.0066 16.1 0.0 2.5 3 0 0 3 3 3 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFM80250.1 - 0.043 14.3 0.5 0.093 13.3 0.5 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 KFM80250.1 - 0.057 12.0 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family DUF4953 PF16313.5 KFM80250.1 - 0.1 11.8 0.7 0.18 11.0 0.1 1.6 2 0 0 2 2 2 0 Met-zincin Reprolysin_5 PF13688.6 KFM80250.1 - 0.13 12.4 0.5 0.27 11.4 0.5 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Translin PF01997.16 KFM80250.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Translin family Ribosomal_L39 PF00832.20 KFM80250.1 - 0.18 11.5 3.0 0.36 10.5 1.3 2.4 2 0 0 2 2 2 0 Ribosomal L39 protein UPF0047 PF01894.17 KFM80253.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 p450 PF00067.22 KFM80254.1 - 7.4e-103 344.8 1.1 9.3e-103 344.4 1.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 HLH PF00010.26 KFM80255.1 - 1.9e-16 59.8 3.3 2.4e-16 59.4 3.3 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain LRR_8 PF13855.6 KFM80256.1 - 1.5e-16 59.9 2.3 1.8e-16 59.6 2.3 1.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KFM80256.1 - 8.3e-11 42.0 8.5 4.8e-06 26.8 1.5 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM80256.1 - 1.6e-07 30.9 3.9 0.16 12.6 0.6 3.1 3 0 0 3 3 3 3 Leucine Rich Repeat LRR_6 PF13516.6 KFM80256.1 - 0.00025 20.9 4.3 2.6 8.3 0.1 3.2 3 0 0 3 3 3 3 Leucine Rich repeat LRR_9 PF14580.6 KFM80256.1 - 0.00033 20.2 0.1 0.00036 20.1 0.1 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.6 KFM80256.1 - 0.01 15.8 0.0 0.01 15.8 0.0 1.0 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) zf-Sec23_Sec24 PF04810.15 KFM80257.1 - 0.011 15.7 0.2 0.014 15.5 0.2 1.3 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger 7tm_1 PF00001.21 KFM80258.1 - 3.7e-09 36.3 1.2 4.8e-09 35.9 1.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 KFM80259.1 - 1.7e-48 162.2 41.1 1.8e-13 50.0 3.2 5.3 1 1 4 5 5 5 5 Leucine rich repeat 7tm_1 PF00001.21 KFM80259.1 - 4.4e-29 101.6 10.4 6.8e-29 101.0 10.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 KFM80259.1 - 1.7e-18 66.8 0.8 4.4e-10 39.6 1.0 3.0 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM80259.1 - 4.6e-18 65.0 34.1 4.1e-05 23.9 0.8 6.5 1 1 8 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM80259.1 - 3.8e-11 42.8 13.1 5.1e-05 22.9 0.6 3.2 1 1 2 3 3 3 3 Leucine-rich repeat Ldl_recept_a PF00057.18 KFM80259.1 - 1.2e-08 35.0 11.1 1.2e-08 35.0 11.1 2.1 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A LRR_1 PF00560.33 KFM80259.1 - 3.3e-06 26.9 25.4 0.92 10.3 0.4 9.8 8 2 0 8 8 8 3 Leucine Rich Repeat 7tm_4 PF13853.6 KFM80259.1 - 0.092 12.5 8.0 0.28 10.9 8.0 1.8 1 1 0 1 1 1 0 Olfactory receptor PsbJ PF01788.17 KFM80259.1 - 1.2 9.0 8.3 0.14 12.0 3.5 1.9 2 0 0 2 2 2 0 PsbJ EGF_CA PF07645.15 KFM80260.1 - 8.1e-12 45.2 9.9 8.1e-12 45.2 9.9 6.9 4 2 3 7 7 7 4 Calcium-binding EGF domain cEGF PF12662.7 KFM80260.1 - 5.1e-09 35.9 27.1 4.2e-05 23.4 0.3 5.8 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.27 KFM80260.1 - 0.00024 21.3 9.5 0.00024 21.3 9.5 7.5 6 2 0 6 6 6 3 EGF-like domain EGF_3 PF12947.7 KFM80260.1 - 0.00038 20.6 19.9 0.0026 17.9 8.9 7.5 5 1 2 7 7 7 3 EGF domain Syndecan PF01034.20 KFM80260.1 - 0.0015 18.4 0.1 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain hEGF PF12661.7 KFM80260.1 - 0.0069 17.0 6.8 0.0069 17.0 6.8 8.4 9 0 0 9 9 9 4 Human growth factor-like EGF MtrF PF09472.10 KFM80260.1 - 0.0083 15.5 1.4 0.015 14.7 1.4 1.3 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Podoplanin PF05808.11 KFM80260.1 - 0.0092 16.1 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Podoplanin PTP_tm PF18861.1 KFM80260.1 - 0.15 12.1 0.4 0.34 10.9 0.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DED PF01335.21 KFM80261.1 - 3.9e-14 52.7 0.2 8.9e-14 51.6 0.2 1.6 1 0 0 1 1 1 1 Death effector domain FtsJ PF01728.19 KFM80262.1 - 9.6e-55 185.4 0.0 1.6e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KFM80262.1 - 8.4e-35 120.0 19.8 8.4e-35 120.0 19.8 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3381) RRF PF01765.19 KFM80262.1 - 0.011 15.7 9.5 0.011 15.7 9.5 2.7 2 1 1 3 3 3 0 Ribosome recycling factor AAA_11 PF13086.6 KFM80262.1 - 1.2 8.9 9.3 0.053 13.3 2.8 2.0 2 0 0 2 2 2 0 AAA domain MIF PF01187.18 KFM80263.1 - 7.8e-14 51.9 0.0 8.2e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DHC_N1 PF08385.12 KFM80264.1 - 1.8e-125 419.7 4.4 2.2e-125 419.5 4.4 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KFM80265.1 - 1.3e-129 431.9 0.0 2.7e-127 424.3 0.0 3.3 3 1 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFM80265.1 - 7.9e-117 390.7 12.8 7.9e-117 390.7 12.8 3.4 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KFM80265.1 - 1.8e-67 227.4 0.0 8.2e-67 225.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KFM80265.1 - 1.5e-46 158.2 0.0 1.2e-38 132.5 0.0 5.2 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_5 PF07728.14 KFM80265.1 - 2.3e-30 105.4 0.0 4.6e-12 46.1 0.0 5.8 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM80265.1 - 6e-18 65.4 0.1 0.0042 17.3 0.0 7.0 6 0 0 6 6 5 3 AAA domain Dynein_AAA_lid PF17852.1 KFM80265.1 - 3e-16 59.7 0.0 1.2e-15 57.8 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KFM80265.1 - 1.1e-15 58.3 0.0 0.0024 18.3 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFM80265.1 - 7.6e-13 48.8 0.0 0.0016 18.7 0.0 5.0 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 KFM80265.1 - 1.4e-12 48.4 0.0 1.2 9.5 0.0 6.3 5 0 0 5 5 5 3 AAA ATPase domain AAA_18 PF13238.6 KFM80265.1 - 5.1e-12 46.5 0.0 0.064 13.8 0.0 5.2 4 0 0 4 4 4 3 AAA domain ABC_tran PF00005.27 KFM80265.1 - 9.7e-07 29.4 0.4 0.66 10.5 0.0 4.9 5 0 0 5 5 4 2 ABC transporter AAA_14 PF13173.6 KFM80265.1 - 2.2e-06 27.7 0.0 0.47 10.5 0.0 4.7 5 0 0 5 5 4 2 AAA domain T2SSE PF00437.20 KFM80265.1 - 2.7e-06 26.7 0.0 0.065 12.3 0.0 4.0 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_29 PF13555.6 KFM80265.1 - 3.7e-06 26.6 0.1 0.35 10.6 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KFM80265.1 - 7.6e-06 25.8 0.4 7.7 6.2 0.0 4.5 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.18 KFM80265.1 - 9.1e-06 25.2 0.2 1.3 8.4 0.0 4.5 5 0 0 5 5 4 2 FtsK/SpoIIIE family Rad17 PF03215.15 KFM80265.1 - 1.2e-05 25.4 0.0 1.6 8.6 0.0 4.6 4 0 0 4 4 4 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KFM80265.1 - 1.3e-05 24.7 3.2 0.56 9.6 0.0 4.5 6 0 0 6 6 4 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KFM80265.1 - 4.1e-05 23.9 0.2 0.13 12.6 0.0 4.5 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 KFM80265.1 - 4.6e-05 23.2 2.1 0.18 11.5 0.0 5.4 5 1 0 5 5 5 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFM80265.1 - 6.6e-05 23.2 0.0 2.3 8.7 0.0 4.9 5 0 0 5 5 5 1 RNA helicase AAA_24 PF13479.6 KFM80265.1 - 9.1e-05 22.3 1.4 16 5.2 0.0 5.0 5 0 0 5 5 5 0 AAA domain RsgA_GTPase PF03193.16 KFM80265.1 - 0.00075 19.4 0.1 12 5.8 0.0 3.9 4 0 0 4 4 3 0 RsgA GTPase AAA_lid_1 PF17857.1 KFM80265.1 - 0.00075 19.7 0.0 0.0038 17.4 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain AAA_25 PF13481.6 KFM80265.1 - 0.001 18.7 0.5 0.18 11.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain RuvB_N PF05496.12 KFM80265.1 - 0.0077 16.0 0.0 0.61 9.8 0.0 3.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KFM80265.1 - 0.015 15.3 0.9 6.1 6.9 0.0 4.4 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFM80265.1 - 0.019 14.9 1.0 56 3.6 0.0 4.9 5 0 0 5 5 5 0 NACHT domain Zeta_toxin PF06414.12 KFM80265.1 - 0.035 13.4 0.0 38 3.5 0.0 4.1 3 0 0 3 3 3 0 Zeta toxin AAA_11 PF13086.6 KFM80265.1 - 0.053 13.3 0.0 3.2 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KFM80265.1 - 0.11 12.2 0.0 15 5.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 KFM80265.1 - 0.13 11.8 1.7 31 4.1 0.1 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_9 PF12781.7 KFM80266.1 - 3.3e-74 248.7 0.1 3.3e-74 248.7 0.1 2.4 3 0 0 3 3 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 KFM80266.1 - 1.7e-52 178.6 0.2 4.2e-52 177.3 0.2 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KFM80266.1 - 2.5e-42 144.5 0.0 5.7e-42 143.3 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KFM80266.1 - 1.1e-31 109.4 0.0 5.4e-30 103.9 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KFM80266.1 - 3.6e-21 75.6 1.9 5.6e-21 74.9 1.9 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor PI3K_P85_iSH2 PF16454.5 KFM80266.1 - 0.0005 19.7 1.0 0.0017 18.0 1.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FapA PF03961.13 KFM80266.1 - 0.00061 18.5 6.3 0.0081 14.8 0.8 2.3 2 0 0 2 2 2 1 Flagellar Assembly Protein A DUF4795 PF16043.5 KFM80266.1 - 0.00071 19.2 0.8 0.00071 19.2 0.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) TelA PF05816.11 KFM80266.1 - 0.00087 18.4 1.2 0.00087 18.4 1.2 2.3 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) DUF948 PF06103.11 KFM80266.1 - 0.0041 17.3 2.0 1.1 9.6 0.2 2.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) APG17 PF04108.12 KFM80266.1 - 0.007 15.5 1.2 0.007 15.5 1.2 2.4 2 0 0 2 2 2 1 Autophagy protein Apg17 UPF0242 PF06785.11 KFM80266.1 - 0.056 13.5 9.1 0.016 15.3 2.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF5344 PF17279.2 KFM80266.1 - 0.068 13.8 7.7 1.7 9.2 2.3 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5344) DUF4337 PF14235.6 KFM80266.1 - 0.1 12.7 4.8 0.73 9.9 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) HSBP1 PF06825.12 KFM80266.1 - 0.16 11.8 0.3 1.8 8.5 0.0 2.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 FH2 PF02181.23 KFM80266.1 - 0.2 10.8 7.2 0.035 13.2 1.0 2.4 2 0 0 2 2 2 0 Formin Homology 2 Domain Seryl_tRNA_N PF02403.22 KFM80266.1 - 0.28 11.4 11.7 0.15 12.3 5.0 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 KFM80266.1 - 0.3 10.3 6.7 0.033 13.4 0.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein FadA PF09403.10 KFM80266.1 - 0.32 11.5 8.8 0.25 11.8 5.0 2.8 2 0 0 2 2 2 0 Adhesion protein FadA Fez1 PF06818.15 KFM80266.1 - 0.5 10.8 12.6 2.2 8.7 4.3 2.6 2 0 0 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 KFM80266.1 - 0.57 10.4 15.0 0.12 12.6 4.9 3.1 2 2 0 3 3 2 0 TATA element modulatory factor 1 TATA binding HD_3 PF13023.6 KFM80266.1 - 0.65 9.9 4.7 0.35 10.8 1.5 2.1 3 0 0 3 3 1 0 HD domain HAUS-augmin3 PF14932.6 KFM80266.1 - 0.68 9.5 15.2 3.3 7.2 5.4 2.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2730 PF10805.8 KFM80266.1 - 0.7 10.0 3.7 1.5 8.9 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) XhlA PF10779.9 KFM80266.1 - 0.86 9.8 4.3 17 5.7 0.9 3.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF1451 PF07295.11 KFM80266.1 - 0.88 9.6 9.0 3.9 7.5 0.0 3.7 3 1 0 3 3 3 0 Zinc-ribbon containing domain KxDL PF10241.9 KFM80266.1 - 0.9 9.9 8.2 0.5 10.7 0.9 3.6 3 0 0 3 3 3 0 Uncharacterized conserved protein Laminin_I PF06008.14 KFM80266.1 - 1.1 8.9 11.2 0.16 11.7 4.1 2.4 2 0 0 2 2 2 0 Laminin Domain I DUF724 PF05266.14 KFM80266.1 - 1.1 9.0 9.7 0.33 10.8 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) SF-assemblin PF06705.11 KFM80266.1 - 1.5 8.1 7.9 0.15 11.4 2.4 2.0 2 0 0 2 2 2 0 SF-assemblin/beta giardin BLOC1_2 PF10046.9 KFM80266.1 - 1.7 9.0 8.8 1.9 8.8 3.1 3.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.9 KFM80266.1 - 1.9 8.7 13.6 0.2 11.9 4.6 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4201 PF13870.6 KFM80266.1 - 2.2 8.0 12.4 0.84 9.3 3.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 KFM80266.1 - 2.3 8.4 17.4 0.04 14.1 6.1 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 KFM80266.1 - 2.4 7.2 8.9 0.1 11.7 1.6 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 KFM80266.1 - 2.7 8.5 11.3 38 4.8 0.1 3.8 2 1 0 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 KFM80266.1 - 2.8 6.7 19.0 0.79 8.6 8.8 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 KFM80266.1 - 3.2 7.5 5.3 2.1 8.1 0.5 2.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.8 KFM80266.1 - 3.8 7.6 17.9 0.019 15.0 5.9 2.9 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 KFM80266.1 - 4.4 6.5 14.2 0.12 11.7 6.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 KFM80266.1 - 4.6 7.3 17.2 0.46 10.5 6.5 3.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KFM80266.1 - 4.8 6.5 15.1 0.25 10.7 6.7 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 KFM80266.1 - 5.4 5.1 13.4 0.17 10.0 3.9 2.6 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA THOC7 PF05615.13 KFM80266.1 - 6.6 7.0 15.2 0.51 10.6 0.5 3.0 2 1 1 3 3 2 0 Tho complex subunit 7 DUF5082 PF16888.5 KFM80266.1 - 6.9 7.0 7.6 4.8 7.5 2.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DHR10 PF18595.1 KFM80266.1 - 7.1 6.7 17.6 2.8 8.0 5.1 3.9 3 1 1 4 4 3 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 KFM80266.1 - 7.8 6.7 9.1 2.7 8.2 2.6 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KFM80266.1 - 7.8 7.0 9.2 17 5.9 1.0 3.6 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) ERM PF00769.19 KFM80266.1 - 8.6 6.1 14.7 0.16 11.8 6.6 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RPW8 PF05659.11 KFM80266.1 - 8.8 6.0 9.5 0.79 9.4 0.8 3.2 3 1 0 3 3 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Prefoldin_2 PF01920.20 KFM80266.1 - 9.5 6.2 10.9 6.7 6.7 0.5 3.9 3 1 1 4 4 3 0 Prefoldin subunit zf-C4H2 PF10146.9 KFM80266.1 - 9.6 6.5 6.8 1.6 9.0 0.4 2.6 3 0 0 3 3 3 0 Zinc finger-containing protein RNase_P_Rpp14 PF01900.19 KFM80267.1 - 4.7e-07 30.0 0.0 6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family THOC7 PF05615.13 KFM80268.1 - 1.7e-27 96.3 5.7 1.7e-27 96.3 5.7 1.8 2 0 0 2 2 2 1 Tho complex subunit 7 DASH_Spc34 PF08657.10 KFM80268.1 - 0.016 15.0 5.0 0.019 14.8 5.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 PI-TkoII_IV PF18714.1 KFM80268.1 - 0.073 12.5 0.4 0.32 10.5 0.1 1.9 1 1 1 2 2 2 0 DNA polymerase II intein Domain IV DUF4238 PF14022.6 KFM80268.1 - 0.15 11.5 2.2 0.17 11.4 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) HlyD_2 PF12700.7 KFM80268.1 - 0.19 10.5 8.8 0.23 10.2 8.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4407 PF14362.6 KFM80268.1 - 1.1 8.5 7.6 1.6 8.0 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KFM80268.1 - 1.2 9.2 5.6 1.8 8.7 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 KFM80268.1 - 2.8 6.7 6.9 3.1 6.6 6.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 KFM80268.1 - 5.3 6.5 11.5 6.1 6.3 11.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 KFM80268.1 - 6.7 6.5 14.4 27 4.5 14.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Peptidase_A17 PF05380.13 KFM80269.1 - 7.7e-16 58.5 0.1 7.9e-16 58.5 0.1 1.0 1 0 0 1 1 1 1 Pao retrotransposon peptidase Flavin_Reduct PF01613.18 KFM80272.1 - 0.093 12.8 0.0 0.093 12.8 0.0 1.0 1 0 0 1 1 1 0 Flavin reductase like domain Patched PF02460.18 KFM80273.1 - 0.0003 19.0 0.5 0.0018 16.5 0.0 2.0 2 0 0 2 2 2 2 Patched family Patched PF02460.18 KFM80274.1 - 2e-17 62.6 11.4 2.7e-17 62.2 11.4 1.2 1 0 0 1 1 1 1 Patched family Lectin_C PF00059.21 KFM80275.1 - 6.4e-95 313.2 24.6 2.3e-21 76.6 0.7 6.4 6 0 0 6 6 6 6 Lectin C-type domain Xlink PF00193.17 KFM80275.1 - 3.2e-08 33.8 1.1 1.4 9.4 0.0 5.2 5 0 0 5 5 5 3 Extracellular link domain UL45 PF05473.12 KFM80275.1 - 4.9e-06 26.3 17.0 0.018 14.7 0.1 5.4 6 1 1 7 7 7 3 UL45 protein, carbohydrate-binding C-type lectin-like DUF5075 PF16825.5 KFM80275.1 - 0.00029 20.6 0.1 3.2 7.4 0.0 4.6 5 0 0 5 5 5 1 IGP family C-type lectin domain Intimin_C PF07979.11 KFM80275.1 - 0.00032 21.1 0.1 24 5.4 0.0 5.2 6 0 0 6 6 6 2 Intimin C-type lectin domain Lectin_C PF00059.21 KFM80276.1 - 1.8e-05 25.4 0.1 9.1e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 KFM80276.1 - 0.00015 21.5 0.1 0.00022 20.9 0.1 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 KFM80277.1 - 2e-56 189.3 19.4 5.2e-22 78.6 3.0 3.2 3 0 0 3 3 3 3 Lectin C-type domain Xlink PF00193.17 KFM80277.1 - 6.2e-05 23.3 0.1 0.26 11.7 0.0 3.7 3 0 0 3 3 3 2 Extracellular link domain UL45 PF05473.12 KFM80277.1 - 0.00015 21.4 0.5 0.00015 21.4 0.5 3.5 4 1 0 4 4 4 1 UL45 protein, carbohydrate-binding C-type lectin-like DUF5075 PF16825.5 KFM80277.1 - 0.012 15.3 0.3 1.8 8.3 0.0 3.0 3 1 0 3 3 3 0 IGP family C-type lectin domain Lectin_C PF00059.21 KFM80278.1 - 0.0054 17.5 0.6 0.016 15.9 0.2 1.8 2 0 0 2 2 2 1 Lectin C-type domain SAP PF02037.27 KFM80279.1 - 7.7e-10 38.3 0.4 7.7e-10 38.3 0.4 1.9 2 1 1 3 3 3 1 SAP domain PASTA PF03793.19 KFM80279.1 - 0.00046 20.0 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 PASTA domain Ish1 PF10281.9 KFM80279.1 - 0.0084 16.4 0.1 0.038 14.3 0.0 1.9 1 1 1 2 2 2 1 Putative stress-responsive nuclear envelope protein LEM PF03020.15 KFM80279.1 - 0.039 13.5 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 LEM domain SNARE_assoc PF09335.11 KFM80280.1 - 4.3e-08 33.7 1.6 3e-07 31.0 0.1 2.9 2 1 1 3 3 3 1 SNARE associated Golgi protein Bac_rhodopsin PF01036.18 KFM80280.1 - 0.017 14.7 2.2 0.37 10.3 0.1 2.5 2 0 0 2 2 2 0 Bacteriorhodopsin-like protein MerE PF05052.12 KFM80280.1 - 0.1 12.5 0.3 0.39 10.7 0.3 2.0 1 0 0 1 1 1 0 MerE protein DUF720 PF05302.11 KFM80281.1 - 1.9 8.4 8.7 0.37 10.6 2.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF720) Prp19 PF08606.11 KFM80282.1 - 3.1e-34 116.8 2.5 4.9e-34 116.1 2.5 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.15 KFM80282.1 - 4.3e-05 23.6 0.0 8.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KFM80282.1 - 0.00085 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Pro-rich_19 PF15455.6 KFM80282.1 - 0.026 13.7 0.1 0.028 13.6 0.1 1.1 1 0 0 1 1 1 0 Proline-rich 19 Rtf2 PF04641.12 KFM80282.1 - 0.041 13.3 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger PAS_11 PF14598.6 KFM80282.1 - 0.13 12.4 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 PAS domain WD40 PF00400.32 KFM80283.1 - 1.3e-30 104.9 8.9 4.6e-07 30.4 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM80283.1 - 7.1e-14 51.9 0.0 0.013 15.7 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM80283.1 - 3.8e-06 26.1 0.9 1.5 7.7 0.0 4.0 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFM80283.1 - 0.00047 20.1 0.1 0.49 10.2 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFM80283.1 - 0.0025 16.6 0.3 0.65 8.6 0.1 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KFM80283.1 - 0.0028 17.0 0.0 0.062 12.6 0.0 2.2 1 1 1 2 2 2 2 WD40-like domain Glyco_transf_10 PF00852.19 KFM80284.1 - 4.5e-50 169.8 0.8 7.6e-50 169.1 0.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFM80284.1 - 1.6e-27 96.2 1.6 1.6e-27 96.2 1.6 2.1 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Lig_chan PF00060.26 KFM80285.1 - 7.1e-27 94.1 0.0 1e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 KFM80285.1 - 6.6e-09 35.5 0.0 1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFM80287.1 - 5.7e-15 55.3 0.0 6.2e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Methyltransf_34 PF11312.8 KFM80288.1 - 4.6e-06 26.1 0.0 8.5e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase MFS_1 PF07690.16 KFM80289.1 - 5.8e-69 232.7 22.0 5.9e-64 216.2 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM80289.1 - 3.2e-09 36.2 17.9 3.2e-08 32.9 17.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM80290.1 - 5.6e-60 203.1 23.0 1.1e-58 198.9 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFM80290.1 - 0.00033 20.1 2.1 0.00033 20.1 2.1 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Ni_hydr_CYTB PF01292.20 KFM80290.1 - 0.13 11.9 6.0 2.4 7.7 1.2 3.1 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 ESSS PF10183.9 KFM80290.1 - 0.18 12.0 0.2 0.92 9.7 0.2 2.2 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Exostosin PF03016.15 KFM80291.1 - 2.4e-27 95.9 0.0 3.4e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Exostosin family PIG-X PF08320.12 KFM80292.1 - 0.00012 22.1 0.2 0.00023 21.1 0.2 1.5 1 1 0 1 1 1 1 PIG-X / PBN1 TMCO5 PF14992.6 KFM80292.1 - 0.027 14.1 0.0 0.03 13.9 0.0 1.0 1 0 0 1 1 1 0 TMCO5 family Ribosomal_S13_N PF08069.12 KFM80293.1 - 1.2e-31 108.5 0.1 1.9e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KFM80293.1 - 6.2e-08 32.7 0.2 9.6e-08 32.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 LexA_DNA_bind PF01726.16 KFM80293.1 - 0.054 13.3 0.1 1.9 8.3 0.0 2.3 2 1 0 2 2 2 0 LexA DNA binding domain DUF3140 PF11338.8 KFM80293.1 - 0.091 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) zf-B_box PF00643.24 KFM80294.1 - 2.2e-08 34.1 9.4 2.2e-08 34.1 9.4 3.5 2 1 0 2 2 2 1 B-box zinc finger MATH PF00917.26 KFM80294.1 - 6.2e-08 32.8 1.0 4.2e-06 26.9 0.0 3.6 2 1 1 3 3 3 1 MATH domain zf-C3HC4_3 PF13920.6 KFM80294.1 - 0.00013 21.8 16.9 0.00013 21.8 16.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM80294.1 - 0.0032 17.3 19.1 0.0032 17.3 19.1 3.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Baculo_PEP_C PF04513.12 KFM80294.1 - 0.14 12.2 6.9 0.27 11.3 1.9 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KFM80294.1 - 1.7 7.1 2.6 2.7 6.4 2.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fungal_TACC PF12709.7 KFM80294.1 - 9.6 6.7 11.7 6.4 7.3 2.3 4.1 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins PAXIP1_C PF15364.6 KFM80295.1 - 2e-32 112.3 1.7 2.8e-32 111.9 1.7 1.2 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein Lig_chan-Glu_bd PF10613.9 KFM80296.1 - 0.0003 20.9 0.0 0.0003 20.9 0.0 1.0 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site zf-primase PF09329.11 KFM80297.1 - 0.043 13.6 0.4 9 6.2 0.0 2.4 2 0 0 2 2 2 0 Primase zinc finger Catalase PF00199.19 KFM80301.1 - 2.4e-111 372.6 0.1 2.9e-111 372.3 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFM80301.1 - 1.7e-23 82.6 0.1 3.5e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive LMSTEN PF07988.12 KFM80301.1 - 0.0084 15.6 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 LMSTEN motif GST_C_3 PF14497.6 KFM80305.1 - 1.4e-16 60.5 0.5 2.5e-16 59.7 0.3 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFM80305.1 - 1.5e-14 54.0 0.1 5.9e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFM80305.1 - 6.2e-12 45.6 0.1 1.1e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM80305.1 - 3.4e-06 27.0 0.1 6.5e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFM80305.1 - 0.0028 17.4 0.6 0.012 15.4 0.6 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM80305.1 - 0.0062 16.9 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DDE_3 PF13358.6 KFM80306.1 - 0.0085 15.9 0.1 0.0085 15.9 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CRAL_TRIO PF00650.20 KFM80307.1 - 1.6e-24 86.5 0.1 2.3e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM80307.1 - 9.1e-08 32.2 2.3 4.5e-07 29.9 1.2 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM80307.1 - 6.9e-06 26.3 0.1 1.2e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM80308.1 - 1.6e-24 86.4 0.1 2.6e-24 85.8 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM80308.1 - 5.1e-05 23.4 0.3 0.0001 22.4 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM80308.1 - 0.0001 22.5 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM80309.1 - 0.0031 17.3 0.0 0.0076 16.0 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CbiA PF01656.23 KFM80309.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Chorismate_bind PF00425.18 KFM80309.1 - 0.21 11.1 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 chorismate binding enzyme zf-LITAF-like PF10601.9 KFM80310.1 - 1.4e-22 79.7 11.2 1.6e-22 79.5 11.2 1.0 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Mpv17_PMP22 PF04117.12 KFM80310.1 - 0.025 14.8 0.1 0.031 14.5 0.1 1.2 1 0 0 1 1 1 0 Mpv17 / PMP22 family DUF2614 PF11023.8 KFM80310.1 - 3.9 7.6 5.3 5.5 7.1 0.9 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain MoCF_biosynth PF00994.24 KFM80314.1 - 6.4e-27 94.0 0.0 8e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 KFM80314.1 - 5.4e-13 48.9 0.0 9.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) OAF PF14941.6 KFM80315.1 - 4.6e-104 347.2 1.3 5.4e-104 346.9 1.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator, Out at first Epiglycanin_C PF14654.6 KFM80316.1 - 8 6.6 8.6 2.2 8.4 5.7 1.6 1 1 1 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region DUF872 PF05915.12 KFM80317.1 - 0.07 13.3 0.3 0.08 13.1 0.3 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) MFS_1 PF07690.16 KFM80320.1 - 3.1e-28 98.7 16.9 4.7e-22 78.4 10.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM80320.1 - 0.00067 18.6 15.9 0.0019 17.1 10.1 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter Pam17 PF08566.10 KFM80320.1 - 8.7 6.2 6.7 7 6.5 0.3 2.9 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 Cas_CXXC_CXXC PF09706.10 KFM80321.1 - 0.063 13.5 0.5 0.063 13.5 0.5 2.2 2 1 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Fer4 PF00037.27 KFM80321.1 - 0.5 10.3 4.7 9 6.3 0.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain 60KD_IMP PF02096.20 KFM80322.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein Cullin_binding PF03556.15 KFM80324.1 - 6.7e-40 136.3 6.9 1.1e-39 135.6 1.1 2.2 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 KFM80324.1 - 4e-10 39.4 0.0 1.7e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain Serpin PF00079.20 KFM80324.1 - 0.084 12.2 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) RRM_1 PF00076.22 KFM80326.1 - 1.3e-22 79.4 0.0 1.7e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM80326.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif S-methyl_trans PF02574.16 KFM80327.1 - 3.1e-44 151.8 0.0 4.2e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase THAP PF05485.12 KFM80327.1 - 6.7e-14 52.6 3.7 6.7e-14 52.6 3.7 2.1 2 0 0 2 2 2 1 THAP domain SBP_bac_3 PF00497.20 KFM80329.1 - 0.00045 19.7 0.0 0.00052 19.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 KFM80329.1 - 0.016 15.0 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel Phage_holin_3_6 PF07332.11 KFM80329.1 - 0.057 13.5 0.0 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III TPR_14 PF13428.6 KFM80330.1 - 2.7e-18 65.1 0.3 1.3e-06 28.8 0.0 5.4 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFM80330.1 - 4.7e-14 51.3 0.1 3.3e-05 23.7 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM80330.1 - 2.1e-10 40.9 1.0 0.00017 22.0 0.0 3.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM80330.1 - 3.6e-09 36.1 0.0 0.00042 20.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM80330.1 - 4.1e-09 36.2 0.1 0.052 13.9 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM80330.1 - 1e-07 32.4 0.0 8.3e-05 23.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM80330.1 - 8.1e-07 28.5 0.0 0.026 13.7 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM80330.1 - 2.4e-06 27.1 0.0 0.0009 19.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM80330.1 - 0.00033 20.3 0.4 0.057 13.1 0.0 3.2 2 1 2 4 4 4 1 TPR repeat TPR_6 PF13174.6 KFM80330.1 - 0.0014 19.2 0.0 9.2 7.1 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat FAT PF02259.23 KFM80330.1 - 0.003 16.8 0.7 0.0038 16.5 0.7 1.2 1 0 0 1 1 1 1 FAT domain NARP1 PF12569.8 KFM80330.1 - 0.0054 15.7 0.0 0.16 10.8 0.0 2.2 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 KFM80330.1 - 0.0057 16.9 0.0 3.1e+02 1.7 0.0 3.9 2 1 0 3 3 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 KFM80330.1 - 0.0084 14.9 0.0 0.1 11.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 KFM80330.1 - 0.016 15.4 0.0 0.19 11.9 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KFM80330.1 - 0.023 13.8 1.1 0.15 11.2 0.8 2.5 1 1 1 2 2 2 0 NRDE-2, necessary for RNA interference ChAPs PF09295.10 KFM80330.1 - 0.026 13.5 0.0 9.8 5.1 0.0 2.7 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) NatB_MDM20 PF09797.9 KFM80330.1 - 0.032 13.2 0.1 0.053 12.4 0.1 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DDE_Tnp_ISL3 PF01610.17 KFM80330.1 - 0.081 12.6 0.9 0.16 11.7 0.6 1.6 2 0 0 2 2 2 0 Transposase TPR_14 PF13428.6 KFM80331.1 - 1.9e-05 25.1 0.1 2.1e-05 24.9 0.1 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 KFM80332.1 - 2.2e-55 187.9 0.1 3.8e-55 187.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFM80332.1 - 2.9e-27 95.1 0.0 5.1e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glutaredoxin PF00462.24 KFM80332.1 - 1.8e-19 69.7 0.0 3.4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Pyr_redox PF00070.27 KFM80332.1 - 5.4e-19 68.5 0.9 6.7e-15 55.4 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM80332.1 - 3.1e-13 49.7 0.1 2.2e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM80332.1 - 1.2e-06 28.0 2.4 1.5e-06 27.5 1.3 1.8 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFM80332.1 - 2.4e-06 27.0 0.1 0.0012 18.2 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFM80332.1 - 3.5e-06 26.4 0.7 7.7e-06 25.2 0.7 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KFM80332.1 - 7.5e-05 22.3 0.1 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFM80332.1 - 0.0027 16.5 0.1 0.0056 15.4 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KFM80332.1 - 0.0029 16.9 0.1 0.006 15.9 0.1 1.5 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 KFM80332.1 - 0.0039 16.4 0.0 0.049 12.8 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFM80332.1 - 0.0089 15.6 0.0 0.022 14.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thioredoxin_2 PF13098.6 KFM80332.1 - 0.021 15.3 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain NAD_binding_7 PF13241.6 KFM80332.1 - 0.022 15.2 0.6 0.42 11.1 0.0 2.7 2 1 1 3 3 3 0 Putative NAD(P)-binding Thioredoxin_3 PF13192.6 KFM80332.1 - 0.034 14.2 0.0 0.098 12.7 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 KFM80332.1 - 0.059 13.5 0.3 7.1 6.8 0.2 3.0 2 1 1 3 3 3 0 Thioredoxin DUF836 PF05768.14 KFM80332.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) NAD_binding_8 PF13450.6 KFM80332.1 - 0.91 9.8 5.4 0.13 12.5 0.8 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TMEM151 PF14857.6 KFM80333.1 - 2.2e-45 155.4 11.9 2.3e-45 155.3 11.9 1.0 1 0 0 1 1 1 1 TMEM151 family DUF3543 PF12063.8 KFM80335.1 - 0.086 12.2 0.1 0.09 12.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) DUF4179 PF13786.6 KFM80335.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) GCIP PF13324.6 KFM80336.1 - 2e-05 24.4 0.0 3.8e-05 23.4 0.0 1.4 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Rieske PF00355.26 KFM80337.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain AAA PF00004.29 KFM80338.1 - 6.4e-44 149.6 0.0 1.3e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM80338.1 - 1.7e-11 43.7 0.1 3.6e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFM80338.1 - 9.8e-09 35.0 0.6 1.9e-08 34.1 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KFM80338.1 - 2.1e-08 34.8 0.2 2.9e-05 24.5 0.0 2.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KFM80338.1 - 4.5e-06 26.7 0.2 0.00013 21.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM80338.1 - 4.9e-06 26.8 0.8 0.0071 16.6 0.0 2.8 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 KFM80338.1 - 1.5e-05 24.8 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFM80338.1 - 2.9e-05 24.3 0.1 0.00011 22.4 0.0 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KFM80338.1 - 0.0034 17.8 0.0 0.0081 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 KFM80338.1 - 0.0037 16.5 0.0 0.009 15.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KFM80338.1 - 0.0041 16.9 0.0 0.009 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFM80338.1 - 0.0059 17.2 0.0 0.024 15.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 KFM80338.1 - 0.0081 16.0 1.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 KFM80338.1 - 0.0084 15.7 0.2 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_14 PF13173.6 KFM80338.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFM80338.1 - 0.013 15.4 0.0 0.049 13.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFM80338.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFM80338.1 - 0.013 15.7 0.0 0.038 14.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KFM80338.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KFM80338.1 - 0.018 14.7 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFM80338.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KFM80338.1 - 0.023 13.9 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KFM80338.1 - 0.029 14.1 0.0 0.09 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KFM80338.1 - 0.046 13.4 0.6 4.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase ATPase PF06745.13 KFM80338.1 - 0.053 12.9 0.1 0.65 9.3 0.0 2.3 1 1 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 KFM80338.1 - 0.064 13.0 0.0 0.21 11.3 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFM80338.1 - 0.065 12.8 0.0 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFM80338.1 - 0.079 12.9 0.0 0.19 11.7 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KFM80338.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFM80338.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Fib_alpha PF08702.10 KFM80338.1 - 0.23 11.7 1.0 0.55 10.4 1.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.6 KFM80338.1 - 3.2 8.2 7.5 1.3e+02 3.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain CSN8_PSD8_EIF3K PF10075.9 KFM80339.1 - 3.6e-32 111.3 0.0 5.3e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KFM80339.1 - 4e-06 26.4 0.3 5.4e-06 26.0 0.3 1.2 1 0 0 1 1 1 1 SAC3/GANP family Grp7_allergen PF16984.5 KFM80340.1 - 1.5e-08 34.9 0.0 1.9e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Group 7 allergen DUF5032 PF16435.5 KFM80341.1 - 0.012 15.1 0.4 0.014 14.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5032) Ribosomal_L16 PF00252.18 KFM80342.1 - 0.14 12.1 0.0 0.15 12.0 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein L16p/L10e LRR_8 PF13855.6 KFM80344.1 - 5.6e-20 70.9 0.9 1.1e-07 31.5 0.0 4.8 2 2 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFM80344.1 - 2.9e-11 43.4 1.1 0.00037 20.8 0.0 5.3 3 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM80344.1 - 7.1e-10 38.9 0.0 1.5e-06 28.2 0.0 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM80344.1 - 8.2e-09 35.2 0.0 7.1e-06 25.6 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFM80344.1 - 0.0021 18.3 3.8 1.9e+02 3.3 0.0 6.9 7 1 1 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 KFM80345.1 - 0.00036 20.2 0.1 0.0009 19.0 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KFM80345.1 - 0.023 15.1 0.5 0.82 10.2 0.1 2.3 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Helicase_C PF00271.31 KFM80346.1 - 1.6e-18 67.1 0.0 1.7e-17 63.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TUDOR PF00567.24 KFM80346.1 - 1.5e-16 60.5 0.2 2e-15 56.9 0.0 2.4 2 0 0 2 2 2 1 Tudor domain HA2 PF04408.23 KFM80346.1 - 7.8e-12 45.4 0.0 1.6e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 KFM80346.1 - 0.0059 16.4 0.4 0.011 15.5 0.4 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CD34_antigen PF06365.12 KFM80346.1 - 0.012 15.2 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Glyco_tran_WecB PF03808.13 KFM80346.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Vta1_C PF18097.1 KFM80346.1 - 0.22 11.3 0.4 0.4 10.4 0.4 1.5 1 0 0 1 1 1 0 Vta1 C-terminal domain SRF-TF PF00319.18 KFM80348.1 - 3.9e-20 71.1 0.1 7e-20 70.3 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Plk4_PB1 PF18190.1 KFM80352.1 - 7.5e-10 38.9 0.3 8.9e-10 38.7 0.3 1.1 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 1 Plk4_PB2 PF18409.1 KFM80352.1 - 6.3e-05 23.6 0.1 9.2e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 2 Pkinase PF00069.25 KFM80354.1 - 2.4e-49 168.1 0.0 2.7e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM80354.1 - 2.8e-31 108.7 0.0 3.4e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM80354.1 - 3.6e-10 39.2 0.0 4.7e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM80354.1 - 5.6e-07 29.2 0.0 7.4e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFM80354.1 - 4.3e-06 26.5 0.0 1.6e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFM80354.1 - 5.1e-05 23.3 0.0 7.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM80354.1 - 0.00039 19.8 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFM80354.1 - 0.035 13.7 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KFM80354.1 - 0.035 13.0 0.1 0.056 12.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain HSP70 PF00012.20 KFM80355.1 - 6.6e-10 37.8 0.0 7e-10 37.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 KFM80356.1 - 3.9e-74 249.9 0.0 4.4e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM80356.1 - 0.00068 18.6 0.0 0.00074 18.4 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Raco_middle PF17651.1 KFM80356.1 - 0.0086 15.8 0.2 0.71 9.5 0.0 2.4 3 0 0 3 3 3 2 RACo middle region HSP70 PF00012.20 KFM80357.1 - 1.1e-11 43.7 0.0 1.1e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 KFM80358.1 - 1.6e-09 36.6 6.7 2e-09 36.2 2.0 2.0 2 0 0 2 2 2 2 Hsp70 protein NPV_P10 PF05531.12 KFM80358.1 - 0.12 12.8 0.3 10 6.6 0.1 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Z1 PF10593.9 KFM80358.1 - 2 7.8 6.5 11 5.5 6.5 2.0 1 1 0 1 1 1 0 Z1 domain Adeno_terminal PF02459.15 KFM80362.1 - 0.085 11.2 0.3 0.086 11.2 0.3 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF3206 PF11472.8 KFM80363.1 - 0.28 11.2 2.7 8.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) DUF1765 PF08578.10 KFM80363.1 - 0.31 11.5 8.1 0.37 11.2 1.8 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1765) DUF3971 PF13116.6 KFM80364.1 - 0.076 12.6 0.2 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function HK PF02110.15 KFM80364.1 - 0.2 11.0 0.1 0.38 10.1 0.1 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Pox_D5 PF03288.16 KFM80364.1 - 4.8 7.7 6.0 28 5.3 0.4 4.0 4 0 0 4 4 4 0 Poxvirus D5 protein-like KxDL PF10241.9 KFM80366.1 - 0.12 12.6 4.6 0.082 13.2 1.9 2.2 2 1 1 3 3 3 0 Uncharacterized conserved protein HTH_50 PF18024.1 KFM80366.1 - 0.15 11.7 1.4 0.61 9.7 0.3 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain PDE4_UCR PF18100.1 KFM80366.1 - 0.53 10.9 6.2 4.6 7.9 0.9 2.2 1 1 1 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) Pdase_C33_assoc PF14756.6 KFM80367.1 - 0.21 11.5 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase_C33-associated domain UCR_UQCRX_QCR9 PF05365.12 KFM80369.1 - 0.11 12.5 0.6 0.13 12.2 0.6 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like 7TM_GPCR_Srw PF10324.9 KFM80370.1 - 2e-36 125.9 15.6 3.6e-36 125.1 15.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KFM80370.1 - 1.9e-17 63.5 14.2 2.4e-17 63.1 14.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFM80370.1 - 4.5e-06 26.5 11.4 8.1e-06 25.6 11.4 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx amfpi-1 PF12190.8 KFM80371.1 - 4.4e-06 27.2 7.7 5.4e-06 26.9 7.7 1.1 1 0 0 1 1 1 1 Fungal protease inhibitor IGFBP PF00219.18 KFM80371.1 - 0.076 13.7 15.6 0.14 12.8 15.6 1.5 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Kinesin PF00225.23 KFM80373.1 - 3.2e-29 101.9 0.3 3.4e-29 101.8 0.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain Yop-YscD_cpl PF16697.5 KFM80374.1 - 1.1e-11 44.8 0.1 2.2e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KFM80374.1 - 2.3e-08 34.3 0.3 3.8e-08 33.6 0.3 1.4 1 0 0 1 1 1 1 FHA domain DUF3987 PF13148.6 KFM80374.1 - 0.0041 16.2 2.8 0.0057 15.7 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) PVL_ORF50 PF07768.11 KFM80374.1 - 0.038 14.3 2.6 0.056 13.8 2.6 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family Kinesin_assoc PF16183.5 KFM80374.1 - 0.038 14.1 5.4 1.9 8.6 0.0 2.6 2 1 1 3 3 3 0 Kinesin-associated Exonuc_VII_L PF02601.15 KFM80374.1 - 0.043 13.4 0.7 0.045 13.3 0.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Membralin PF09746.9 KFM80374.1 - 0.091 11.8 0.3 0.11 11.6 0.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein APG6_N PF17675.1 KFM80374.1 - 0.11 13.0 8.6 0.16 12.5 8.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region SspP PF08179.12 KFM80375.1 - 0.17 12.3 0.4 0.18 12.3 0.4 1.1 1 0 0 1 1 1 0 Small acid-soluble spore protein P family P2X_receptor PF00864.19 KFM80377.1 - 3.8e-55 187.5 0.1 4.2e-55 187.3 0.1 1.0 1 0 0 1 1 1 1 ATP P2X receptor UPF0014 PF03649.13 KFM80377.1 - 0.011 15.0 0.8 0.017 14.5 0.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) Polysacc_synt_3 PF13440.6 KFM80377.1 - 0.047 12.9 0.2 0.06 12.5 0.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein tRNA_m1G_MT PF01746.21 KFM80377.1 - 0.2 11.4 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase RWD PF05773.22 KFM80378.1 - 1.1e-17 64.4 3.9 5.2e-17 62.2 1.3 2.1 2 0 0 2 2 2 1 RWD domain HTH_22 PF13309.6 KFM80378.1 - 0.14 12.2 1.0 0.46 10.6 0.5 2.0 2 0 0 2 2 2 0 HTH domain Rep_fac_C PF08542.11 KFM80379.1 - 3.1e-24 85.2 0.4 8.4e-23 80.6 0.2 2.4 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 KFM80379.1 - 3.9e-17 62.9 0.0 6.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFM80379.1 - 2.9e-16 59.7 0.0 9.5e-12 45.0 0.0 2.2 1 1 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KFM80379.1 - 4.8e-09 36.4 0.0 8.5e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KFM80379.1 - 3.6e-05 24.2 0.0 6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 KFM80379.1 - 5.1e-05 23.2 0.0 0.00057 19.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KFM80379.1 - 7.2e-05 23.1 0.7 0.31 11.3 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_24 PF13479.6 KFM80379.1 - 7.6e-05 22.5 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KFM80379.1 - 9.1e-05 22.7 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 KFM80379.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KFM80379.1 - 0.00017 21.7 0.0 0.09 12.8 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DNA_pol3_delta PF06144.13 KFM80379.1 - 0.0012 18.7 1.1 0.0015 18.4 0.2 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DUF815 PF05673.13 KFM80379.1 - 0.0013 18.0 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TniB PF05621.11 KFM80379.1 - 0.0019 17.7 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 KFM80379.1 - 0.0039 17.2 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM80379.1 - 0.0045 17.3 0.1 0.018 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KFM80379.1 - 0.0051 16.6 0.1 0.071 12.9 0.0 2.3 1 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 KFM80379.1 - 0.0055 16.2 0.1 0.23 10.9 0.0 2.3 1 1 1 2 2 2 1 PhoH-like protein AAA_5 PF07728.14 KFM80379.1 - 0.0069 16.4 0.3 0.049 13.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KFM80379.1 - 0.0074 16.0 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFM80379.1 - 0.026 13.7 0.0 0.064 12.5 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 KFM80379.1 - 0.028 13.9 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFM80379.1 - 0.032 13.6 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI YfdX PF10938.8 KFM80379.1 - 0.033 14.1 0.1 0.2 11.6 0.0 2.1 1 1 1 2 2 2 0 YfdX protein AAA_3 PF07726.11 KFM80379.1 - 0.038 13.8 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFM80379.1 - 0.039 14.2 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 KFM80379.1 - 0.044 12.5 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain IstB_IS21 PF01695.17 KFM80379.1 - 0.049 13.4 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein RecR PF02132.15 KFM80379.1 - 0.16 11.6 0.4 0.43 10.2 0.4 1.7 1 0 0 1 1 1 0 RecR protein HSP70 PF00012.20 KFM80380.1 - 1.5e-260 865.6 8.8 1.7e-260 865.4 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM80380.1 - 4.1e-18 65.3 0.3 2.5e-16 59.4 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KFM80380.1 - 0.014 15.8 3.0 5.7 7.4 0.2 3.4 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 KFM80380.1 - 0.11 11.8 1.5 0.16 11.2 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 KFM80380.1 - 0.16 11.7 0.0 0.53 10.0 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain 6PGD PF00393.19 KFM80380.1 - 0.61 9.4 2.5 1.7 8.0 0.1 2.1 2 0 0 2 2 2 0 6-phosphogluconate dehydrogenase, C-terminal domain PG_binding_1 PF01471.18 KFM80381.1 - 1.1e-09 38.3 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain EF-hand_7 PF13499.6 KFM80382.1 - 4.2e-25 88.0 0.8 7.5e-19 68.0 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM80382.1 - 1.2e-20 71.4 0.5 8.1e-07 28.2 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFM80382.1 - 5.1e-18 63.4 1.0 0.00035 20.3 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFM80382.1 - 8.1e-15 53.6 0.4 3.3e-06 26.3 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFM80382.1 - 1.2e-11 44.2 7.4 0.001 18.9 1.6 3.8 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM80382.1 - 0.00016 21.9 2.7 0.0091 16.3 0.1 3.4 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFM80382.1 - 0.00059 19.7 0.8 0.29 11.1 0.0 3.3 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFM80382.1 - 0.038 14.2 1.0 0.83 9.9 0.4 2.6 2 1 0 2 2 1 0 Dockerin type I domain EF-hand_9 PF14658.6 KFM80382.1 - 0.043 14.1 0.2 6.1 7.2 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain Caleosin PF05042.13 KFM80382.1 - 1.3 8.9 6.5 21 5.0 0.5 3.4 2 1 2 4 4 4 0 Caleosin related protein FG-GAP PF01839.23 KFM80382.1 - 2.2 8.5 3.9 1.9 8.7 0.1 2.5 3 0 0 3 3 3 0 FG-GAP repeat Ank_2 PF12796.7 KFM80384.1 - 2.5e-09 37.6 0.0 3.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM80384.1 - 6.4e-08 33.0 0.3 5.8e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM80384.1 - 1.6e-06 27.9 0.1 0.067 13.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KFM80384.1 - 8.1e-06 26.1 0.5 0.066 13.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFM80384.1 - 5.7e-05 23.3 0.2 0.0027 18.0 0.1 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) GATase_7 PF13537.6 KFM80384.1 - 0.17 11.8 0.0 0.71 9.8 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase domain Ank_2 PF12796.7 KFM80385.1 - 4e-07 30.5 0.1 5.7e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM80385.1 - 3.8e-06 26.8 0.1 0.092 13.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KFM80385.1 - 3.7e-05 24.0 0.9 0.044 14.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFM80385.1 - 0.00026 21.5 0.4 0.00071 20.1 0.3 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM80385.1 - 0.00056 20.2 0.1 0.0057 16.9 0.2 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) NMT1 PF09084.11 KFM80385.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 NMT1/THI5 like Ank_5 PF13857.6 KFM80386.1 - 0.084 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) AbiEi_4 PF13338.6 KFM80386.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Ank_5 PF13857.6 KFM80387.1 - 5.5e-09 36.1 0.3 5.6e-06 26.5 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM80387.1 - 8.1e-09 36.0 3.6 0.0038 17.8 0.1 3.3 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM80387.1 - 3.8e-07 30.5 0.4 0.0031 18.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM80387.1 - 6.4e-06 26.4 0.3 0.013 15.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFM80387.1 - 0.00059 20.1 0.1 4.8 8.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat NAM-associated PF14303.6 KFM80387.1 - 0.0042 17.8 0.0 0.0075 17.0 0.0 1.4 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain MID_MedPIWI PF18296.1 KFM80387.1 - 0.025 14.4 1.6 0.038 13.8 1.6 1.2 1 0 0 1 1 1 0 MID domain of medPIWI YdaS_antitoxin PF15943.5 KFM80387.1 - 0.17 11.7 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeodomain PF00046.29 KFM80387.1 - 0.21 11.5 0.6 0.78 9.6 0.0 2.2 3 0 0 3 3 3 0 Homeodomain Ank_2 PF12796.7 KFM80388.1 - 7.8e-14 52.0 0.0 1.1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM80388.1 - 1.3e-10 41.5 0.4 1.8e-06 28.4 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM80388.1 - 5.4e-10 39.3 0.0 4e-06 27.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM80388.1 - 1.2e-09 37.5 0.1 0.00069 19.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFM80388.1 - 1.6e-07 31.5 0.1 0.022 15.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat SNAPc_SNAP43 PF09808.9 KFM80389.1 - 4.8e-30 104.9 0.0 5.9e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF5617 PF18493.1 KFM80389.1 - 0.17 12.0 0.4 0.43 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) zf-RING_2 PF13639.6 KFM80390.1 - 6.9e-07 29.5 10.2 6.9e-07 29.5 10.2 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KFM80390.1 - 4e-06 26.7 9.0 4e-06 26.7 9.0 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFM80390.1 - 4.2e-05 23.2 7.0 4.2e-05 23.2 7.0 2.8 3 1 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 KFM80390.1 - 0.00021 21.1 8.8 0.00021 21.1 8.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM80390.1 - 0.0047 16.9 3.8 0.0047 16.9 3.8 3.6 3 1 1 4 4 4 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFM80390.1 - 3.6 7.7 15.9 0.49 10.5 5.5 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 KFM80390.1 - 8 6.9 16.9 3 8.2 7.0 2.9 2 1 0 2 2 2 0 RING-like domain zf-C2H2 PF00096.26 KFM80392.1 - 2.1e-09 37.3 8.0 5.4e-06 26.6 1.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80392.1 - 7.1e-07 29.5 5.9 0.00011 22.8 0.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM80392.1 - 1.9e-06 28.0 7.8 0.00025 21.3 1.4 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFM80392.1 - 2.2e-06 27.8 0.1 2.2e-06 27.8 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM80392.1 - 2.6e-05 24.4 5.7 0.0023 18.2 1.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM80392.1 - 0.0002 21.1 0.5 0.00021 21.1 0.5 1.0 1 0 0 1 1 1 1 GAGA factor zf-C2HC_2 PF13913.6 KFM80392.1 - 0.0041 17.0 0.7 1.2 9.1 0.1 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM80392.1 - 0.0089 16.1 0.3 0.012 15.6 0.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 KFM80392.1 - 0.011 15.7 6.9 0.038 14.0 2.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger C1_4 PF07975.12 KFM80392.1 - 0.017 15.3 3.1 0.022 15.0 3.1 1.2 1 0 0 1 1 1 0 TFIIH C1-like domain zf-Di19 PF05605.12 KFM80392.1 - 0.027 14.7 3.8 0.031 14.6 3.8 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KFM80392.1 - 0.069 12.8 0.5 0.069 12.8 0.5 1.7 1 1 1 2 2 2 0 MYST family zinc finger domain zf-LYAR PF08790.11 KFM80392.1 - 0.13 12.1 2.1 8.1 6.5 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_8 PF15909.5 KFM80392.1 - 0.16 12.3 3.4 0.17 12.2 3.4 1.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-DBF PF07535.12 KFM80392.1 - 0.66 10.1 6.0 0.54 10.4 1.7 2.1 2 0 0 2 2 2 0 DBF zinc finger zf-H2C2_2 PF13465.6 KFM80393.1 - 4.9e-15 55.2 25.5 1.6e-06 28.2 0.7 4.7 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80393.1 - 2.8e-13 49.5 28.8 4.2e-05 23.8 1.1 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80393.1 - 4.5e-09 36.4 27.7 0.0001 22.8 0.8 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFM80393.1 - 8.9e-07 29.1 25.5 5.3e-05 23.5 0.8 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type GAGA PF09237.11 KFM80393.1 - 1e-05 25.2 2.1 0.041 13.7 0.3 2.2 1 1 1 2 2 2 2 GAGA factor zf-C2H2_jaz PF12171.8 KFM80393.1 - 1.8e-05 24.9 16.6 0.0042 17.3 0.4 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM80393.1 - 0.00088 19.2 0.5 0.00088 19.2 0.5 4.8 4 1 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM80393.1 - 0.018 14.9 0.5 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KFM80393.1 - 0.038 13.9 6.5 0.71 9.8 0.2 3.9 3 1 0 3 3 3 0 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM80393.1 - 0.05 13.6 0.1 0.05 13.6 0.1 2.8 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger zf-C2H2_7 PF15269.6 KFM80393.1 - 0.079 13.1 0.7 0.079 13.1 0.7 3.3 1 1 3 4 4 4 0 Zinc-finger zf-MYST PF17772.1 KFM80393.1 - 0.2 11.3 0.2 0.2 11.3 0.2 3.2 2 1 2 4 4 4 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 KFM80393.1 - 1.9 8.9 14.7 0.37 11.1 0.6 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KFM80393.1 - 4.3 7.1 15.1 1.2 8.8 1.9 3.2 1 1 3 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Cadherin PF00028.17 KFM80394.1 - 1.5e-119 390.8 15.6 1.4e-19 70.3 0.4 8.1 8 0 0 8 8 8 8 Cadherin domain Cadherin_3 PF16184.5 KFM80394.1 - 4.1e-11 42.9 8.7 0.23 11.5 0.1 6.2 5 1 1 6 6 6 5 Cadherin-like RET_CLD1 PF17756.1 KFM80394.1 - 7.7e-09 35.9 0.0 7.5e-05 23.0 0.0 5.2 5 1 0 5 5 5 1 RET Cadherin like domain 1 Cadherin_2 PF08266.12 KFM80394.1 - 5e-07 29.5 0.1 1.2 9.0 0.0 4.5 4 1 0 4 4 4 3 Cadherin-like Cadherin_pro PF08758.11 KFM80394.1 - 0.0011 19.1 0.0 0.21 11.7 0.0 4.1 4 0 0 4 4 4 1 Cadherin prodomain like DUF3364 PF11844.8 KFM80394.1 - 0.55 10.5 2.5 11 6.4 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3364) JAB PF01398.21 KFM80396.1 - 6.8e-13 48.6 0.1 1e-12 48.0 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KFM80396.1 - 0.00083 19.4 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) SRP_TPR_like PF17004.5 KFM80397.1 - 3.1e-21 75.6 18.9 7.4e-21 74.4 5.7 4.1 4 0 0 4 4 4 1 Putative TPR-like repeat TPR_19 PF14559.6 KFM80397.1 - 3.5e-21 75.5 20.4 7.9e-06 26.3 0.0 8.9 3 3 4 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM80397.1 - 3.6e-19 68.8 27.6 9.6e-07 28.9 1.0 6.9 4 2 4 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 SRP72 PF08492.12 KFM80397.1 - 4.5e-19 68.6 9.3 4.5e-19 68.6 9.3 3.0 3 0 0 3 3 3 1 SRP72 RNA-binding domain TPR_2 PF07719.17 KFM80397.1 - 4.9e-18 63.7 26.3 0.1 12.8 0.3 10.4 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFM80397.1 - 1.1e-17 63.2 7.9 0.033 15.0 0.1 10.0 7 2 4 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM80397.1 - 9.5e-15 55.0 5.4 0.047 14.4 0.1 7.9 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFM80397.1 - 2.8e-14 52.7 9.9 3.3 8.5 0.1 10.0 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM80397.1 - 2.5e-11 43.7 16.5 0.15 12.4 0.0 7.7 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFM80397.1 - 3.7e-08 32.9 29.3 0.087 12.7 0.1 9.1 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFM80397.1 - 4.2e-08 32.7 7.8 5.7 7.2 0.1 8.4 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM80397.1 - 4.4e-08 32.7 27.3 0.57 10.5 0.0 8.9 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_21 PF09976.9 KFM80397.1 - 5.6e-08 32.7 13.8 1.1e-06 28.5 0.6 4.5 1 1 3 5 5 5 2 Tetratricopeptide repeat-like domain PPR PF01535.20 KFM80397.1 - 2.6e-05 24.1 10.7 5.9 7.4 0.0 7.2 9 0 0 9 9 6 2 PPR repeat TPR_11 PF13414.6 KFM80397.1 - 2.7e-05 23.7 9.0 0.063 13.0 0.1 4.4 5 0 0 5 5 3 2 TPR repeat PPR_2 PF13041.6 KFM80397.1 - 3.1e-05 24.1 2.3 15 5.9 0.0 6.3 7 0 0 7 7 5 0 PPR repeat family TPR_9 PF13371.6 KFM80397.1 - 0.0002 21.4 10.9 4.4 7.5 0.0 7.1 6 2 3 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM80397.1 - 0.0025 18.1 8.3 7.6 7.2 0.0 7.5 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM80397.1 - 0.0025 17.2 10.9 0.011 15.2 0.6 4.4 1 1 4 5 5 5 2 MalT-like TPR region BTAD PF03704.17 KFM80397.1 - 0.007 16.8 4.2 0.82 10.1 0.2 3.8 4 1 1 5 5 4 1 Bacterial transcriptional activator domain DUF4874 PF16173.5 KFM80397.1 - 0.025 14.3 0.5 0.094 12.4 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) DUF4919 PF16266.5 KFM80397.1 - 0.039 13.9 0.1 0.039 13.9 0.1 2.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4919) TPR_4 PF07721.14 KFM80397.1 - 0.048 14.3 5.3 0.47 11.2 0.0 4.8 7 0 0 7 7 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KFM80397.1 - 0.23 11.5 4.2 41 4.3 0.0 4.2 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 5 DUF1039 PF06287.11 KFM80397.1 - 0.88 10.0 3.7 14 6.2 0.1 4.1 4 1 0 4 4 3 0 Protein of unknown function (DUF1039) Rogdi_lz PF10259.9 KFM80397.1 - 1.1 8.7 8.9 0.35 10.3 2.7 2.6 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein TPR_10 PF13374.6 KFM80397.1 - 1.2 9.1 4.7 57 3.8 0.1 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Chitin_bind_4 PF00379.23 KFM80399.1 - 1.1e-10 41.9 10.5 1.5e-10 41.5 10.5 1.2 1 0 0 1 1 1 1 Insect cuticle protein DUF3963 PF13124.6 KFM80399.1 - 0.72 9.9 2.6 1.2 9.2 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) MFS_1_like PF12832.7 KFM80401.1 - 3.1e-64 217.2 16.5 3.6e-64 217.0 16.5 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM80401.1 - 9.4e-15 54.4 32.2 1.4e-06 27.5 0.3 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 KFM80401.1 - 0.001 18.0 27.3 0.056 12.2 1.0 3.1 2 1 1 3 3 3 2 LacY proton/sugar symporter DUF4083 PF13314.6 KFM80401.1 - 0.22 11.5 2.9 0.6 10.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) MFS_1_like PF12832.7 KFM80402.1 - 1.3e-65 221.8 17.9 1.5e-65 221.5 17.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM80402.1 - 7.9e-18 64.5 35.1 3.3e-07 29.6 0.1 3.8 2 1 2 4 4 4 3 Major Facilitator Superfamily MFS_2 PF13347.6 KFM80402.1 - 6.4e-07 28.3 19.9 7.6e-05 21.4 14.4 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein LacY_symp PF01306.19 KFM80402.1 - 0.008 15.0 23.3 0.06 12.1 0.9 2.5 2 1 0 2 2 2 2 LacY proton/sugar symporter MFS_1 PF07690.16 KFM80403.1 - 0.023 13.6 0.0 0.023 13.6 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Chordopox_A13L PF05961.11 KFM80403.1 - 0.033 14.4 0.2 0.037 14.2 0.2 1.2 1 0 0 1 1 1 0 Chordopoxvirus A13L protein HIG_1_N PF04588.13 KFM80403.1 - 0.059 13.6 0.3 0.079 13.2 0.3 1.2 1 0 0 1 1 1 0 Hypoxia induced protein conserved region DUF4199 PF13858.6 KFM80403.1 - 0.069 13.5 0.2 0.079 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4083 PF13314.6 KFM80403.1 - 0.12 12.3 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) MFS_1_like PF12832.7 KFM80404.1 - 5.7e-44 150.5 7.2 7.3e-44 150.2 7.2 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM80404.1 - 4.1e-11 42.4 5.8 9.3e-09 34.7 0.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFM80404.1 - 1.6e-07 30.2 14.0 0.00038 19.1 2.1 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFM80405.1 - 1.2e-52 179.1 12.2 1.4e-52 178.9 12.2 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM80405.1 - 1.2e-13 50.7 49.6 2.9e-09 36.3 24.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFM80405.1 - 2e-06 26.7 11.7 2e-06 26.7 11.7 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein Nuc_H_symport PF03825.16 KFM80405.1 - 0.00017 20.7 14.9 0.00027 20.1 14.9 1.3 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 KFM80405.1 - 0.00023 20.1 13.7 0.0005 18.9 13.7 1.5 1 1 0 1 1 1 1 LacY proton/sugar symporter Sugar_tr PF00083.24 KFM80405.1 - 0.16 10.8 14.9 0.025 13.5 8.6 2.7 2 2 0 2 2 2 0 Sugar (and other) transporter Pox_A14 PF05767.12 KFM80405.1 - 1.8 8.8 7.0 2.3 8.4 0.4 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Insulin_TMD PF17870.1 KFM80405.1 - 2 8.5 0.0 2 8.5 0.0 3.2 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment MFS_1_like PF12832.7 KFM80406.1 - 7.7e-16 57.9 1.8 1.1e-15 57.4 1.8 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM80406.1 - 1.3e-07 30.9 0.7 1.5e-07 30.7 0.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFM80406.1 - 0.0023 16.6 0.5 0.0023 16.5 0.5 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein LacY_symp PF01306.19 KFM80406.1 - 0.023 13.5 0.6 0.028 13.2 0.6 1.2 1 0 0 1 1 1 0 LacY proton/sugar symporter CIMR PF00878.18 KFM80407.1 - 4e-16 59.4 3.2 2.3e-15 56.9 1.1 2.3 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 KFM80407.1 - 0.0014 17.8 0.4 0.3 10.1 0.1 2.0 1 1 1 2 2 2 2 Mannose-6-phosphate receptor CIMR PF00878.18 KFM80408.1 - 5.2e-52 175.7 6.2 8.2e-29 100.5 0.3 2.8 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KFM80408.1 - 1.4e-08 34.9 3.6 2e-08 34.4 0.2 2.5 1 1 2 3 3 3 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KFM80408.1 - 6.8e-07 28.6 0.5 0.019 14.1 0.1 2.9 1 1 2 3 3 3 2 Mannose-6-phosphate receptor CIMR PF00878.18 KFM80409.1 - 3.2e-49 166.7 9.0 2.7e-18 66.4 0.2 3.1 3 0 0 3 3 3 3 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KFM80409.1 - 2.5e-13 50.5 7.7 9.3e-06 25.7 0.3 3.4 1 1 2 3 3 3 3 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KFM80409.1 - 6.9e-08 31.9 2.3 0.0015 17.7 0.2 2.1 2 0 0 2 2 2 2 Mannose-6-phosphate receptor DUF2733 PF10813.8 KFM80409.1 - 0.21 11.4 1.5 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Citrate_bind PF16114.5 KFM80410.1 - 1e-43 148.9 1.7 1.1e-43 148.8 1.7 1.0 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Cas9_PI PF16595.5 KFM80412.1 - 0.0088 15.9 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 PAM-interacting domain of CRISPR-associated endonuclease Cas9 RT_RNaseH_2 PF17919.1 KFM80412.1 - 0.1 12.7 0.1 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RCC1 PF00415.18 KFM80414.1 - 3.1e-75 248.6 21.7 6.2e-14 52.4 0.0 9.5 10 0 0 10 10 10 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM80414.1 - 7.5e-40 134.0 38.4 2.7e-08 33.4 0.2 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Clathrin PF00637.20 KFM80414.1 - 0.002 18.0 1.1 0.062 13.2 0.1 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_3 PF07720.12 KFM80414.1 - 0.62 10.1 4.6 0.46 10.5 1.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Tmemb_40 PF10160.9 KFM80418.1 - 3.5e-57 193.8 8.0 4.1e-57 193.6 8.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein JAMP PF05571.12 KFM80418.1 - 0.022 14.4 4.5 0.036 13.7 4.5 1.3 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein Fun_ATP-synt_8 PF05933.13 KFM80418.1 - 2.2 8.5 7.4 14 5.9 2.0 2.6 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) DUF4695 PF15766.5 KFM80419.1 - 2.2e-08 34.2 0.7 3.7e-08 33.6 0.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4695) MIP PF00230.20 KFM80420.1 - 1.5e-69 234.1 12.0 1.8e-69 234.0 12.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Diphthamide_syn PF01866.17 KFM80420.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative diphthamide synthesis protein SelB-wing_3 PF09107.11 KFM80421.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix zf-H2C2_2 PF13465.6 KFM80422.1 - 6.6e-58 190.7 67.6 1.9e-07 31.2 2.6 11.2 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80422.1 - 5.4e-52 171.5 93.0 6.9e-06 26.2 1.0 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80422.1 - 2.3e-34 115.1 87.8 0.0021 18.8 0.6 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM80422.1 - 3.2e-25 87.6 64.8 2.3e-05 24.3 0.6 11.5 11 1 0 11 11 11 10 C2H2-type zinc finger zf-met PF12874.7 KFM80422.1 - 1.2e-15 57.3 71.7 0.013 15.9 0.2 11.3 11 0 0 11 11 11 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM80422.1 - 6.9e-14 51.7 64.0 0.071 13.4 0.2 11.1 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM80422.1 - 1.3e-05 25.0 27.4 0.66 10.0 0.9 7.2 5 3 2 7 7 7 5 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 KFM80422.1 - 0.0048 17.0 27.5 0.79 9.9 0.5 6.7 4 2 4 8 8 8 3 Zinc ribbon domain DUF2256 PF10013.9 KFM80422.1 - 0.011 15.8 31.9 24 5.2 0.0 10.2 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) Chal_sti_synt_N PF00195.19 KFM80422.1 - 0.029 13.8 9.1 0.38 10.1 0.6 3.2 1 1 1 3 3 3 0 Chalcone and stilbene synthases, N-terminal domain zinc_ribbon_15 PF17032.5 KFM80422.1 - 0.056 14.2 40.6 0.73 10.6 2.7 6.0 1 1 5 6 6 6 0 zinc-ribbon family DNA_pol3_chi PF04364.13 KFM80422.1 - 0.11 12.6 6.7 2.2 8.5 0.1 4.7 4 2 3 7 7 6 0 DNA polymerase III chi subunit, HolC BolA PF01722.18 KFM80422.1 - 0.11 12.7 0.6 0.11 12.7 0.6 4.9 1 1 4 5 5 5 0 BolA-like protein zf-C2HC_2 PF13913.6 KFM80422.1 - 0.15 12.0 28.8 2.7 8.0 0.0 9.0 9 0 0 9 9 9 0 zinc-finger of a C2HC-type PHF5 PF03660.14 KFM80422.1 - 0.16 12.2 37.3 0.35 11.1 1.3 5.8 1 1 5 6 6 6 0 PHF5-like protein zf_ZIC PF18366.1 KFM80422.1 - 0.41 10.8 51.5 0.2 11.8 0.5 9.5 2 2 7 9 9 9 0 Zic proteins zinc finger domain zf_UBZ PF18439.1 KFM80422.1 - 0.46 10.1 43.3 0.82 9.3 0.1 9.8 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger HNH_5 PF14279.6 KFM80422.1 - 1.1 9.2 48.7 0.86 9.5 2.1 9.6 7 2 1 8 8 8 0 HNH endonuclease zf-MYST PF17772.1 KFM80422.1 - 1.8 8.2 47.5 0.45 10.2 0.3 9.4 5 2 5 10 10 10 0 MYST family zinc finger domain zf-RING_11 PF17123.5 KFM80422.1 - 2.1 8.2 35.9 2.6 7.9 3.1 8.8 10 0 0 10 10 9 0 RING-like zinc finger GAGA PF09237.11 KFM80422.1 - 2.4 8.0 31.9 1.7 8.5 0.3 7.8 2 2 6 9 9 9 0 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM80422.1 - 4.4 7.4 44.5 4.1 7.5 0.2 9.8 11 0 0 11 11 11 0 Sec23/Sec24 zinc finger SF3A2 PF16835.5 KFM80423.1 - 3.5e-38 129.9 0.1 5.3e-38 129.3 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KFM80423.1 - 3.6e-07 30.3 2.0 7.7e-07 29.3 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KFM80423.1 - 0.00032 20.6 0.2 0.00062 19.7 0.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KFM80423.1 - 0.072 12.7 3.2 0.12 11.9 3.2 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Lipoprotein_10 PF03202.13 KFM80425.1 - 0.1 13.0 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region WD40 PF00400.32 KFM80427.1 - 1.7e-18 66.6 7.9 3.3e-07 30.9 0.3 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat DRTGG PF07085.12 KFM80427.1 - 0.0012 18.6 0.4 0.24 11.2 0.1 2.1 2 0 0 2 2 2 2 DRTGG domain ANAPC4_WD40 PF12894.7 KFM80427.1 - 0.0017 18.6 0.3 0.017 15.4 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM80427.1 - 0.0036 16.0 1.5 1.1 7.9 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFM80427.1 - 0.057 12.4 0.2 0.61 9.0 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DHFR_2 PF06442.11 KFM80427.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 R67 dihydrofolate reductase WD40 PF00400.32 KFM80428.1 - 2.4e-21 75.6 28.8 6.4e-07 30.0 1.9 8.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM80428.1 - 2.3e-11 43.8 3.9 0.0011 19.2 0.1 4.5 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM80428.1 - 0.00013 21.4 3.5 0.033 13.5 0.1 2.3 1 1 1 2 2 2 2 WD40-like domain VID27 PF08553.10 KFM80428.1 - 0.0082 15.2 0.0 0.92 8.5 0.0 2.7 2 1 0 2 2 2 2 VID27 C-terminal WD40-like domain NACHT PF05729.12 KFM80429.1 - 1.2e-10 41.6 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFM80429.1 - 5.2e-05 23.7 0.1 0.00015 22.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain DAP3 PF10236.9 KFM80429.1 - 6.8e-05 22.2 0.1 0.00016 21.0 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 KFM80429.1 - 7.2e-05 23.1 0.0 0.00025 21.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain ATPase_2 PF01637.18 KFM80429.1 - 0.00035 20.6 0.0 0.0034 17.4 0.0 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 KFM80429.1 - 0.0092 16.4 0.0 0.021 15.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFM80429.1 - 0.013 15.1 0.1 0.12 11.9 0.0 2.3 2 1 1 3 3 3 0 AAA domain NB-ARC PF00931.22 KFM80429.1 - 0.014 14.6 0.1 0.08 12.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 KFM80429.1 - 0.028 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 KFM80429.1 - 0.03 13.2 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.22 KFM80429.1 - 0.036 14.5 0.1 0.12 12.8 0.1 2.1 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KFM80429.1 - 0.044 14.3 0.3 0.32 11.5 0.4 2.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM80429.1 - 0.044 14.3 0.0 0.098 13.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KFM80429.1 - 0.093 12.6 0.1 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 KFM80429.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.12 KFM80429.1 - 0.22 10.8 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin 7tm_1 PF00001.21 KFM80433.1 - 2e-09 37.2 3.9 2.8e-09 36.7 3.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFM80433.1 - 0.0059 15.9 5.8 0.0059 15.9 5.8 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw SDF PF00375.18 KFM80433.1 - 0.054 12.5 1.7 0.068 12.2 1.7 1.2 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family 7tm_1 PF00001.21 KFM80434.1 - 1.1e-12 47.9 2.7 1.2e-12 47.8 2.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFM80434.1 - 8.8e-06 25.3 2.3 1e-05 25.1 2.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFM80434.1 - 8.1e-05 22.4 1.9 8.3e-05 22.3 1.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFM80434.1 - 8.2e-05 22.5 0.6 8.8e-05 22.4 0.6 1.0 1 0 0 1 1 1 1 Olfactory receptor DUF4212 PF13937.6 KFM80434.1 - 0.13 12.6 1.9 2.4 8.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) MTCP1 PF08991.10 KFM80435.1 - 0.044 14.0 1.6 0.08 13.2 1.6 1.5 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CHCH PF06747.13 KFM80435.1 - 0.074 13.2 6.3 0.11 12.6 6.3 1.3 1 0 0 1 1 1 0 CHCH domain YLP PF02757.17 KFM80435.1 - 4.2 7.7 7.8 2.7 8.2 1.1 2.6 2 0 0 2 2 2 0 YLP motif UCR_hinge PF02320.16 KFM80435.1 - 7.9 6.8 11.3 0.79 10.0 0.3 2.4 2 1 1 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein zf-C2H2 PF00096.26 KFM80436.1 - 2.1e-17 62.5 52.9 0.0022 18.4 5.8 7.0 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80436.1 - 2.1e-17 62.3 49.6 0.0018 18.9 4.0 6.8 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM80436.1 - 3.9e-16 58.6 38.1 3.4e-05 24.0 0.8 7.1 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_8 PF15909.5 KFM80436.1 - 0.00018 21.7 3.0 0.00018 21.7 3.0 3.6 1 1 3 4 4 4 1 C2H2-type zinc ribbon TF_Zn_Ribbon PF08271.12 KFM80436.1 - 0.0021 17.5 8.7 0.0031 17.0 0.0 3.7 4 0 0 4 4 4 1 TFIIB zinc-binding zf-met PF12874.7 KFM80436.1 - 0.039 14.3 3.4 0.039 14.3 3.4 5.4 7 0 0 7 7 5 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KFM80436.1 - 0.18 12.5 16.9 0.38 11.4 4.9 3.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats ADK_lid PF05191.14 KFM80436.1 - 0.29 11.2 10.5 2.3 8.3 3.7 3.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM80436.1 - 0.47 10.8 23.9 3.9 7.9 0.3 5.0 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) HypA PF01155.19 KFM80436.1 - 1.2 9.2 8.3 1 9.4 1.7 2.9 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 KFM80436.1 - 2.5 8.9 10.0 34 5.3 4.5 3.1 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 KFM80436.1 - 2.7 8.4 27.6 4.3 7.7 1.5 6.2 7 0 0 7 7 6 0 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM80436.1 - 2.8 8.1 9.2 9.4 6.4 0.1 4.0 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger zf-Di19 PF05605.12 KFM80436.1 - 4.9 7.5 28.2 8.1 6.8 2.9 4.2 3 2 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFM80436.1 - 6 6.7 30.3 0.32 10.8 0.2 5.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-CRD PF17979.1 KFM80436.1 - 7.2 6.7 15.1 0.13 12.3 3.8 2.6 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions PyrI_C PF02748.15 KFM80436.1 - 8.4 6.4 11.3 58 3.7 0.1 4.5 3 2 2 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CAS_CSE1 PF03378.15 KFM80437.1 - 1.7e-96 323.4 0.0 1.9e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Herpes_BBRF1 PF04793.12 KFM80437.1 - 0.0084 15.2 0.0 0.1 11.6 0.0 2.1 2 0 0 2 2 2 1 BRRF1-like protein UME PF08064.13 KFM80437.1 - 0.062 13.2 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 UME (NUC010) domain PcF PF09461.10 KFM80440.1 - 0.038 14.4 0.3 0.038 14.4 0.3 1.0 1 0 0 1 1 1 0 Phytotoxin PcF protein Ig_2 PF13895.6 KFM80441.1 - 6.3e-17 61.7 3.7 1e-05 25.7 0.2 4.7 3 3 1 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.6 KFM80441.1 - 1.2e-13 51.4 1.9 0.0025 18.4 0.0 3.9 3 2 1 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFM80441.1 - 4.4e-10 39.6 0.9 0.00024 21.2 0.1 4.4 4 1 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM80441.1 - 7.5e-09 35.5 0.1 0.00057 19.9 0.0 2.9 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM80441.1 - 1.7e-08 34.6 0.4 0.00039 20.5 0.1 3.7 3 1 1 4 4 4 2 Immunoglobulin V-set domain I-set PF07679.16 KFM80441.1 - 0.00036 20.5 0.1 1.2 9.3 0.1 3.1 3 1 0 3 3 3 2 Immunoglobulin I-set domain VPS13_mid_rpt PF16910.5 KFM80441.1 - 0.022 14.2 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 Repeating coiled region of VPS13 Vault PF01505.18 KFM80443.1 - 2.2e-64 213.4 2.0 2.2e-17 62.9 0.1 5.3 6 0 0 6 6 6 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 KFM80443.1 - 3.6e-55 185.0 0.1 7.9e-55 184.0 0.1 1.6 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 KFM80443.1 - 4e-37 126.4 0.5 2.9e-23 82.0 0.1 2.8 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 KFM80443.1 - 3e-34 116.9 0.5 1.4e-30 105.1 0.0 3.7 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 KFM80443.1 - 3.3e-32 110.4 0.2 2.3e-30 104.5 0.0 3.8 5 0 0 5 5 5 1 Major Vault Protein repeat domain Band_7 PF01145.25 KFM80443.1 - 0.0012 18.9 0.1 0.0012 18.9 0.1 2.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family NfeD PF01957.18 KFM80443.1 - 0.0083 16.5 1.0 7.9 6.9 0.1 3.9 4 0 0 4 4 4 1 NfeD-like C-terminal, partner-binding DUF3601 PF12208.8 KFM80443.1 - 0.02 14.9 0.1 13 6.0 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) Cation_ATPase_N PF00690.26 KFM80444.1 - 9.3e-09 34.9 0.0 9.9e-09 34.8 0.0 1.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus PUB_1 PF18486.1 KFM80444.1 - 0.1 12.5 0.0 0.1 12.4 0.0 1.0 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain E1-E2_ATPase PF00122.20 KFM80445.1 - 9.2e-52 175.2 0.5 2.5e-51 173.8 0.5 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFM80445.1 - 3.2e-43 147.6 4.7 7.3e-43 146.4 4.7 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFM80445.1 - 1.9e-22 80.6 0.3 2.7e-21 76.8 0.1 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFM80445.1 - 3.6e-18 65.4 0.0 7.6e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFM80445.1 - 3.7e-08 33.4 2.1 5.9e-06 26.2 0.9 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM80445.1 - 1.5e-06 28.7 0.0 8.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.6 KFM80445.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Hydrolase_6 PF13344.6 KFM80445.1 - 0.17 12.0 0.0 0.75 9.9 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3810 PF12725.7 KFM80445.1 - 1.9 7.7 3.8 3.9 6.7 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) WBS_methylT PF12589.8 KFM80446.1 - 3.8e-16 59.6 7.3 7.7e-16 58.6 7.3 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 KFM80446.1 - 4.8e-13 49.6 0.0 8.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM80446.1 - 5.7e-13 49.3 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM80446.1 - 4.1e-07 29.9 0.0 6.3e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM80446.1 - 9.2e-07 29.5 0.0 3.2e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM80446.1 - 1.4e-05 25.0 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 KFM80446.1 - 7.6e-05 22.5 0.0 0.00062 19.6 0.0 2.0 2 0 0 2 2 2 1 DNA methylase Methyltransf_32 PF13679.6 KFM80446.1 - 0.00076 19.5 0.2 0.0012 18.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 KFM80446.1 - 0.0071 16.0 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 KFM80446.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 KFM80446.1 - 0.022 14.4 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 KFM80446.1 - 0.046 13.1 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.13 KFM80446.1 - 0.059 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 KFM80446.1 - 0.082 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KFM80446.1 - 0.083 12.4 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 KFM80446.1 - 0.093 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DnaJ PF00226.31 KFM80447.1 - 4.3e-21 74.8 0.1 7.8e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DEAD PF00270.29 KFM80449.1 - 7.1e-49 165.9 0.0 1.1e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 KFM80449.1 - 6.1e-47 155.7 73.7 6.5e-08 32.3 3.0 7.4 7 0 0 7 7 7 7 Zinc knuckle Helicase_C PF00271.31 KFM80449.1 - 5.7e-31 107.1 0.1 1.2e-30 106.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC_3 PF13917.6 KFM80449.1 - 2.6e-12 46.5 36.1 0.036 14.0 0.7 7.8 3 1 5 8 8 8 7 Zinc knuckle TRAF6_Z2 PF18048.1 KFM80449.1 - 0.00091 19.3 39.7 4.3 7.5 0.8 7.7 8 0 0 8 8 8 6 TNF receptor-associated factor 6 zinc finger 2 ResIII PF04851.15 KFM80449.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC_5 PF14787.6 KFM80449.1 - 0.79 9.5 52.4 0.24 11.1 2.1 7.4 7 0 0 7 7 7 0 GAG-polyprotein viral zinc-finger PMI_typeI PF01238.21 KFM80450.1 - 4.5e-102 342.0 0.0 6.5e-102 341.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 KFM80450.1 - 0.00086 19.2 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 KFM80450.1 - 0.003 17.2 0.0 0.08 12.7 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Innexin PF00876.18 KFM80454.1 - 1.9e-95 320.2 4.2 2.1e-95 320.0 4.2 1.0 1 0 0 1 1 1 1 Innexin MAM PF00629.23 KFM80455.1 - 6e-79 263.5 0.8 2.8e-29 102.1 0.0 3.3 3 0 0 3 3 3 3 MAM domain, meprin/A5/mu PKD PF00801.20 KFM80455.1 - 0.07 13.0 0.5 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 PKD domain DUF4332 PF14229.6 KFM80458.1 - 0.029 14.6 0.0 0.031 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) PFK PF00365.20 KFM80460.1 - 1.1e-207 687.7 4.3 5.3e-109 363.9 1.7 2.0 2 0 0 2 2 2 2 Phosphofructokinase Arm PF00514.23 KFM80461.1 - 5.5e-10 38.9 0.9 0.0054 16.7 0.0 4.1 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 KFM80461.1 - 0.0064 15.1 0.0 0.0084 14.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 KFM80461.1 - 0.017 15.5 0.0 6.8 7.2 0.0 2.5 1 1 0 2 2 2 0 HEAT repeats HEAT PF02985.22 KFM80461.1 - 0.028 14.7 3.0 2.6 8.6 0.1 3.8 4 1 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 KFM80461.1 - 0.054 14.0 0.5 2.7 8.6 0.1 2.8 2 1 1 3 3 3 0 HEAT-like repeat Arm PF00514.23 KFM80462.1 - 0.18 11.9 1.5 0.62 10.2 0.1 1.9 1 1 0 2 2 2 0 Armadillo/beta-catenin-like repeat Chordopox_G2 PF05796.12 KFM80463.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus protein G2 SR-25 PF10500.9 KFM80464.1 - 0.048 13.3 10.3 0.059 13.0 10.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 KFM80464.1 - 0.8 7.9 7.1 0.97 7.6 7.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 KFM80464.1 - 1.7 6.3 5.6 2.1 6.1 5.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CCDC106 PF15794.5 KFM80464.1 - 2.5 7.8 10.0 4.2 7.0 10.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TCP PF03634.13 KFM80464.1 - 4.7 7.8 11.2 6.5 7.3 11.2 1.2 1 0 0 1 1 1 0 TCP family transcription factor Arm PF00514.23 KFM80465.1 - 2.5e-20 71.8 22.9 0.034 14.2 0.5 13.1 13 0 0 13 13 13 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFM80465.1 - 5.4e-13 49.1 1.9 0.0035 17.7 0.1 6.5 4 1 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KFM80465.1 - 2.9e-10 40.4 9.2 0.00053 20.4 0.1 6.9 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 KFM80465.1 - 7.1e-09 35.2 21.5 0.00014 21.9 0.1 10.8 12 0 0 12 12 12 1 HEAT repeat Cnd1 PF12717.7 KFM80465.1 - 2e-06 27.9 3.5 0.0051 16.9 0.0 3.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RICTOR_N PF14664.6 KFM80465.1 - 0.00063 18.8 2.7 0.44 9.5 0.0 3.9 2 1 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, N-term Uso1_p115_head PF04869.14 KFM80465.1 - 0.00083 18.6 2.9 0.011 14.9 0.2 3.3 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Vac14_Fab1_bd PF12755.7 KFM80465.1 - 0.0011 19.5 0.9 0.018 15.6 0.0 3.3 4 0 0 4 4 3 1 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 KFM80465.1 - 0.0063 16.5 11.1 2.6 8.0 0.8 4.6 3 1 1 4 4 4 2 Myosin-binding striated muscle assembly central DUF3361 PF11841.8 KFM80465.1 - 0.043 13.8 9.3 1.6 8.7 0.5 4.3 3 2 1 4 4 4 0 Domain of unknown function (DUF3361) Importin_rep_2 PF18786.1 KFM80465.1 - 0.064 13.1 0.2 0.23 11.3 0.2 2.0 1 0 0 1 1 1 0 Importin 13 repeat IlvC PF01450.19 KFM80465.1 - 0.082 13.2 0.1 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Cohesin_HEAT PF12765.7 KFM80465.1 - 0.1 12.9 0.4 0.5 10.7 0.4 2.2 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion DUF908 PF06012.12 KFM80465.1 - 0.12 11.7 2.0 12 5.1 0.1 3.6 2 1 0 3 3 3 0 Domain of Unknown Function (DUF908) RasGEF_N_2 PF14663.6 KFM80465.1 - 1.2 9.6 11.2 14 6.2 0.0 6.0 4 2 3 7 7 7 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain V-ATPase_H_C PF11698.8 KFM80465.1 - 3.4 7.8 9.5 67 3.6 0.0 5.5 4 1 5 9 9 9 0 V-ATPase subunit H Nif11 PF07862.11 KFM80466.1 - 0.013 15.8 0.4 0.091 13.1 0.4 2.2 1 1 0 1 1 1 0 Nif11 domain Wbp11 PF09429.10 KFM80466.1 - 0.038 14.4 0.6 0.038 14.4 0.6 2.4 1 1 1 2 2 2 0 WW domain binding protein 11 Apt1 PF10351.9 KFM80466.1 - 0.042 12.7 0.7 0.046 12.6 0.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S49_N PF08496.10 KFM80466.1 - 0.17 11.9 0.5 0.24 11.5 0.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DAO PF01266.24 KFM80467.1 - 7.2e-65 219.9 0.0 8.2e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM80467.1 - 0.00024 20.4 0.1 0.0018 17.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM80467.1 - 0.00035 19.8 0.0 0.00055 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAO_M PF16350.5 KFM80467.1 - 0.00083 19.6 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox PF00070.27 KFM80467.1 - 0.0024 18.4 0.1 0.0062 17.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM80467.1 - 0.0041 17.3 0.0 0.0092 16.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFM80467.1 - 0.024 13.9 0.9 0.076 12.2 0.0 1.9 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.21 KFM80467.1 - 0.047 13.0 0.1 0.091 12.1 0.1 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 KFM80467.1 - 0.048 12.9 1.0 0.25 10.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFM80467.1 - 0.064 12.1 0.1 3.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 KFM80467.1 - 0.069 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-C2H2 PF00096.26 KFM80468.1 - 4.4e-50 165.4 83.9 2.9e-05 24.3 1.3 11.5 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM80468.1 - 1.2e-49 164.6 78.7 2.8e-08 33.8 1.2 12.5 12 0 0 12 12 12 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM80468.1 - 1.6e-37 124.9 77.9 0.00083 20.0 0.7 11.5 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM80468.1 - 1.9e-15 56.7 37.8 0.04 14.2 0.1 11.1 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM80468.1 - 1.4e-11 44.1 64.7 0.0014 18.6 0.1 11.5 11 0 0 11 11 11 7 C2H2-type zinc finger zf-met PF12874.7 KFM80468.1 - 2.5e-11 43.6 44.9 0.001 19.4 0.1 9.9 11 0 0 11 11 10 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM80468.1 - 1.3e-09 37.7 55.2 0.00095 18.9 0.6 10.3 11 0 0 11 11 11 6 zinc-finger C2H2-type ADK_lid PF05191.14 KFM80468.1 - 0.0017 18.3 28.1 0.089 12.8 1.3 6.6 5 1 0 5 5 5 2 Adenylate kinase, active site lid C1_1 PF00130.22 KFM80468.1 - 0.0032 17.3 35.0 0.014 15.2 0.4 7.4 3 1 4 8 8 8 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KFM80468.1 - 0.005 16.9 40.1 0.067 13.3 1.3 7.9 6 4 1 7 7 7 3 Zinc ribbon domain DUF3268 PF11672.8 KFM80468.1 - 0.041 14.2 22.9 3.1 8.1 0.4 6.1 4 3 1 5 5 5 0 zinc-finger-containing domain zinc_ribbon_9 PF14369.6 KFM80468.1 - 0.19 12.0 19.8 61 4.0 0.0 7.6 7 1 1 8 8 8 0 zinc-ribbon zinc_ribbon_15 PF17032.5 KFM80468.1 - 0.34 11.7 34.7 3.3 8.5 0.4 6.8 2 1 3 5 5 5 0 zinc-ribbon family zf-C2HE PF16278.5 KFM80468.1 - 1.3 9.5 48.2 1.3 9.6 1.0 9.6 4 2 4 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger DZR PF12773.7 KFM80468.1 - 1.8 8.6 36.4 88 3.2 0.2 6.7 2 1 0 2 2 1 0 Double zinc ribbon HypA PF01155.19 KFM80468.1 - 3.2 7.8 37.0 5.6 7.0 4.6 7.0 3 1 1 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KFM80468.1 - 7.2 7.0 47.1 5.5 7.4 2.3 8.4 4 1 4 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding MRP-L27 PF09809.9 KFM80470.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 DUF5061 PF16587.5 KFM80471.1 - 0.14 12.2 1.6 3.6 7.7 0.3 2.1 1 1 1 2 2 2 0 17 kDa common-antigen outer membrane protein RNase_Zc3h12a PF11977.8 KFM80473.1 - 0.033 14.0 3.0 0.062 13.1 3.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain DUF5004 PF16395.5 KFM80473.1 - 0.062 13.3 5.5 0.081 12.9 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5004) PPDFL PF15060.6 KFM80473.1 - 1.2 9.7 5.0 1.3 9.5 4.1 1.6 1 1 0 1 1 1 0 Differentiation and proliferation regulator Presenilin PF01080.17 KFM80473.1 - 2.5 6.8 10.4 3.6 6.2 10.4 1.3 1 0 0 1 1 1 0 Presenilin CDRT4 PF15213.6 KFM80473.1 - 4.6 7.9 5.6 1.2 9.8 1.2 1.9 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein PAT1 PF09770.9 KFM80473.1 - 4.6 5.4 27.3 5.6 5.1 27.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Aminotran_1_2 PF00155.21 KFM80474.1 - 1e-56 192.7 0.0 1.2e-56 192.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFM80474.1 - 1.6e-06 26.9 0.0 1.2e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFM80474.1 - 0.00021 20.3 0.0 0.0011 18.0 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFM80474.1 - 0.023 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFM80474.1 - 0.054 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2236 PF09995.9 KFM80476.1 - 1.8e-16 61.1 0.0 2.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) P53 PF00870.18 KFM80478.1 - 4.8e-36 124.4 1.5 4.8e-36 124.4 1.5 1.4 1 1 0 1 1 1 1 P53 DNA-binding domain THAP PF05485.12 KFM80480.1 - 8.1e-12 45.9 4.0 9.4e-12 45.7 4.0 1.1 1 0 0 1 1 1 1 THAP domain LIM PF00412.22 KFM80481.1 - 5.1e-42 141.9 56.0 4.2e-11 42.9 4.7 4.1 4 0 0 4 4 4 4 LIM domain PET PF06297.14 KFM80482.1 - 4e-28 97.6 0.0 6.5e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 KFM80482.1 - 5.9e-09 36.0 6.9 5.9e-09 36.0 6.9 2.8 2 1 0 2 2 2 1 LIM domain zf-RING-like PF08746.11 KFM80482.1 - 1.3 9.3 21.0 3.7 7.9 3.0 3.8 3 1 0 3 3 3 0 RING-like domain RNase_H PF00075.24 KFM80483.1 - 6.7e-15 55.5 0.0 1.4e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFM80483.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Exo_endo_phos_2 PF14529.6 KFM80485.1 - 8.6e-25 86.9 0.0 1e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM80485.1 - 4.5e-06 26.4 0.1 5.1e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAD_SOX PF18371.1 KFM80485.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase CNH PF00780.22 KFM80486.1 - 0.022 14.4 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 CNH domain CNH PF00780.22 KFM80487.1 - 2.2e-43 148.8 0.0 3.2e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFM80487.1 - 3e-30 105.5 0.0 4.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM80487.1 - 1.5e-18 67.0 0.0 2.3e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM80487.1 - 0.059 12.1 0.0 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Alk_phosphatase PF00245.20 KFM80489.1 - 2.2e-28 99.4 0.0 2.5e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Lactamase_B_4 PF13691.6 KFM80490.1 - 4.8e-15 55.0 0.0 1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease RNA_pol_Rpa2_4 PF06883.12 KFM80490.1 - 0.044 13.8 0.1 1.2 9.2 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase I, Rpa2 specific domain Lactamase_B_2 PF12706.7 KFM80491.1 - 2.3e-11 43.6 0.5 5.8e-11 42.3 0.5 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFM80491.1 - 0.014 15.4 0.2 0.027 14.5 0.2 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily TPPII PF12580.8 KFM80492.1 - 0.085 12.3 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II tRNA-synt_2 PF00152.20 KFM80493.1 - 1.2e-78 264.4 0.0 1.9e-78 263.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFM80493.1 - 2.5e-13 49.8 0.0 6.5e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFM80493.1 - 5.7e-10 39.1 0.1 0.00017 21.1 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Peptidase_M23 PF01551.22 KFM80493.1 - 0.14 12.3 0.0 0.41 10.9 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M23 Vac14_Fab1_bd PF12755.7 KFM80494.1 - 5.9e-07 30.0 1.3 0.018 15.6 0.0 2.8 1 1 2 3 3 3 2 Vacuolar 14 Fab1-binding region PRESAN PF09687.10 KFM80494.1 - 0.012 16.2 0.8 0.012 16.2 0.8 1.7 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Img2 PF05046.14 KFM80494.1 - 0.014 15.7 0.1 0.044 14.1 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) CLASP_N PF12348.8 KFM80494.1 - 0.026 14.1 0.6 0.059 12.9 0.3 1.6 1 1 0 1 1 1 0 CLASP N terminal HEAT PF02985.22 KFM80494.1 - 0.25 11.7 0.8 14 6.3 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat Vac14_Fab1_bd PF12755.7 KFM80495.1 - 0.0001 22.8 3.1 0.38 11.4 0.0 5.1 4 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region IFN-gamma PF00714.17 KFM80495.1 - 0.00026 20.8 0.3 0.06 13.2 0.0 2.5 2 0 0 2 2 2 2 Interferon gamma TAF6_C PF07571.13 KFM80495.1 - 0.02 15.2 0.4 2 8.8 0.2 3.8 1 1 1 2 2 2 0 TAF6 C-terminal HEAT repeat domain Tti2 PF10521.9 KFM80495.1 - 0.11 12.0 4.7 6.6 6.2 0.1 4.3 4 1 2 6 6 6 0 Tti2 family HEAT_EZ PF13513.6 KFM80495.1 - 0.16 12.5 0.3 42 4.8 0.0 4.1 5 0 0 5 5 5 0 HEAT-like repeat COQ9 PF08511.11 KFM80495.1 - 0.19 11.5 0.3 0.62 9.9 0.3 1.9 1 1 0 1 1 1 0 COQ9 CLASP_N PF12348.8 KFM80495.1 - 0.39 10.2 3.5 1.2 8.7 0.2 3.0 2 1 0 3 3 3 0 CLASP N terminal DUF4560 PF15118.6 KFM80496.1 - 1e-09 38.2 0.7 1.1e-09 38.0 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4560) TM231 PF10149.9 KFM80497.1 - 1.1e-46 159.6 1.6 1.2e-46 159.4 1.6 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 Death PF00531.22 KFM80498.1 - 3.7e-09 36.6 0.0 6e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Death domain CBF_beta PF02312.17 KFM80499.1 - 4.6e-80 267.2 3.0 7.1e-80 266.5 3.0 1.3 1 0 0 1 1 1 1 Core binding factor beta subunit APOBEC4 PF18775.1 KFM80499.1 - 0.091 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 APOBEC4 FYVE PF01363.21 KFM80500.1 - 3e-08 33.7 14.2 3.4e-08 33.5 14.2 1.1 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KFM80500.1 - 0.0034 17.6 11.0 0.004 17.3 11.0 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger PHD PF00628.29 KFM80500.1 - 0.73 9.8 14.5 1.2 9.1 14.5 1.4 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_4 PF13717.6 KFM80500.1 - 4.8 7.2 19.0 6.9 6.7 7.9 3.2 2 1 0 2 2 2 0 zinc-ribbon domain eIF-1a PF01176.19 KFM80501.1 - 1.6e-20 72.6 0.2 2.5e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 HAS-barrel PF09378.10 KFM80501.1 - 0.12 12.6 0.6 0.36 11.0 0.1 2.0 2 1 0 2 2 2 0 HAS barrel domain DUF2475 PF10629.9 KFM80503.1 - 3.4e-06 27.2 3.6 0.00084 19.5 0.7 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF2475) SET_assoc PF11767.8 KFM80503.1 - 0.026 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-H2C2_2 PF13465.6 KFM80505.1 - 2.6e-56 185.6 72.6 2.1e-10 40.5 0.9 9.7 10 0 0 10 10 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80505.1 - 1e-35 120.2 76.3 7.1e-06 26.2 1.7 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80505.1 - 5.8e-29 98.3 70.1 0.00042 20.9 1.3 9.4 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM80505.1 - 3.7e-17 61.9 63.7 3.7e-05 23.6 0.9 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM80505.1 - 2e-08 34.3 67.8 0.021 15.2 0.7 9.5 10 0 0 10 10 9 6 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM80505.1 - 1.4e-06 27.9 1.2 1.4e-06 27.9 1.2 10.3 9 2 0 9 9 9 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM80505.1 - 1.6e-05 25.0 54.3 0.13 12.5 1.1 9.4 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM80505.1 - 0.00015 21.9 4.1 1.7 8.9 0.1 5.5 2 1 5 7 7 7 1 BolA-like protein GAGA PF09237.11 KFM80505.1 - 0.00016 21.4 12.2 0.2 11.5 0.0 4.7 2 2 3 5 5 5 2 GAGA factor zf-C2H2_8 PF15909.5 KFM80505.1 - 0.00041 20.6 41.2 0.16 12.3 4.3 5.0 1 1 4 5 5 5 2 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFM80505.1 - 0.0015 19.3 35.2 1.1 10.0 2.7 5.0 1 1 6 7 7 7 4 zinc-ribbon family CIA30 PF08547.12 KFM80505.1 - 0.056 13.5 0.0 0.23 11.5 0.0 2.0 1 1 0 2 2 2 0 Complex I intermediate-associated protein 30 (CIA30) zf-C2H2_11 PF16622.5 KFM80505.1 - 0.12 12.1 0.0 0.12 12.1 0.0 7.7 9 0 0 9 9 9 0 zinc-finger C2H2-type Noelin-1 PF12308.8 KFM80505.1 - 0.12 12.3 2.3 0.22 11.5 2.3 1.5 1 0 0 1 1 1 0 Neurogenesis glycoprotein zf-C2HC_2 PF13913.6 KFM80505.1 - 1.4 8.9 37.6 4.2 7.4 0.1 8.3 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM80505.1 - 1.4 9.0 35.2 1.9 8.6 3.5 8.0 8 2 1 9 9 9 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 KFM80505.1 - 1.7 9.1 46.9 0.52 10.7 0.8 7.5 2 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM80505.1 - 3.8 7.2 0.0 3.8 7.2 0.0 7.9 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger Zf_RING PF16744.5 KFM80505.1 - 5.4 7.2 38.0 11 6.3 0.1 8.2 2 2 5 9 9 9 0 KIAA1045 RING finger DUF3268 PF11672.8 KFM80505.1 - 5.7 7.3 13.3 19 5.6 0.3 4.1 4 0 0 4 4 4 0 zinc-finger-containing domain ADH_N PF08240.12 KFM80506.1 - 1.8e-12 47.1 0.2 2.3e-12 46.8 0.2 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FLYWCH PF04500.16 KFM80508.1 - 5.2e-12 45.7 0.8 6.1e-12 45.5 0.8 1.0 1 0 0 1 1 1 1 FLYWCH zinc finger domain DDE_Tnp_IS1595 PF12762.7 KFM80509.1 - 0.012 15.6 0.1 0.027 14.5 0.1 1.7 1 1 0 1 1 1 0 ISXO2-like transposase domain Hist_deacetyl PF00850.19 KFM80510.1 - 7.1e-165 547.9 0.0 1.4e-83 280.9 0.0 2.1 2 0 0 2 2 2 2 Histone deacetylase domain zf-UBP PF02148.19 KFM80510.1 - 3.3e-16 59.4 12.8 3.3e-16 59.4 12.8 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DUF3137 PF11335.8 KFM80510.1 - 0.011 15.6 0.8 0.11 12.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3137) DUF5491 PF17595.2 KFM80510.1 - 0.091 13.1 0.1 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5491) zf-UBP_var PF17807.1 KFM80510.1 - 0.097 12.4 5.6 0.049 13.4 1.7 2.6 3 0 0 3 3 3 0 Variant UBP zinc finger DAO PF01266.24 KFM80511.1 - 4.1e-25 89.1 0.0 4.7e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM80511.1 - 0.00034 19.9 0.1 0.33 10.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFM80511.1 - 0.00044 20.3 0.2 0.27 11.2 0.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KFM80511.1 - 0.00074 18.7 0.6 0.33 10.0 0.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFM80511.1 - 0.00081 18.5 0.0 0.32 10.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFM80511.1 - 0.071 12.4 0.1 0.31 10.2 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM80511.1 - 0.19 12.0 1.1 0.42 10.9 1.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM80512.1 - 4.8e-24 85.6 0.0 5.6e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KFM80512.1 - 0.00021 20.5 0.2 0.081 12.0 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KFM80512.1 - 0.00057 19.2 0.0 0.45 9.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFM80512.1 - 0.00082 18.5 0.1 0.1 11.6 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KFM80512.1 - 0.0033 17.4 0.1 0.97 9.4 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KFM80512.1 - 0.0047 16.8 0.1 1.5 8.7 0.0 2.9 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4599 PF15371.6 KFM80512.1 - 0.044 14.3 0.1 0.84 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) Pyr_redox_3 PF13738.6 KFM80512.1 - 0.13 11.5 0.4 0.72 9.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM80512.1 - 0.23 11.7 1.3 0.47 10.7 1.3 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM80513.1 - 8.3e-26 91.4 0.0 1.1e-25 91.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM80513.1 - 3e-05 23.4 0.1 0.13 11.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM80513.1 - 0.00026 20.2 0.2 0.12 11.4 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFM80513.1 - 0.0019 17.3 0.1 0.46 9.5 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KFM80513.1 - 0.0023 17.9 0.3 0.3 11.1 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KFM80513.1 - 0.0097 15.8 0.3 1.9 8.3 0.0 2.7 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KFM80513.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4599 PF15371.6 KFM80513.1 - 0.056 14.0 0.2 2 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) Thi4 PF01946.17 KFM80513.1 - 0.12 11.5 0.1 0.33 10.2 0.1 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KFM80513.1 - 0.14 12.4 1.4 0.34 11.2 1.4 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LRR_8 PF13855.6 KFM80516.1 - 1.4e-24 85.6 46.2 2.3e-08 33.6 11.9 5.5 2 1 3 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 KFM80516.1 - 1.1e-11 44.8 0.2 5.7e-08 32.8 0.0 2.4 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM80516.1 - 3.4e-09 36.8 18.2 3.1e-06 27.4 6.8 6.1 3 3 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM80516.1 - 2.5e-05 23.8 11.5 0.0024 17.4 1.6 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KFM80516.1 - 0.012 15.6 20.6 1.2 9.3 0.8 5.9 5 0 0 5 5 5 0 Leucine Rich repeat FNIP PF05725.12 KFM80516.1 - 0.014 15.6 0.1 0.18 12.0 0.0 3.2 3 1 0 3 3 3 0 FNIP Repeat LRR_1 PF00560.33 KFM80516.1 - 0.08 13.5 43.9 0.72 10.6 1.8 8.9 9 1 1 10 10 10 0 Leucine Rich Repeat Neugrin PF06413.11 KFM80517.1 - 3.6e-09 37.0 10.1 1.7e-07 31.5 6.6 2.8 1 1 1 2 2 2 2 Neugrin MRP-L20 PF12824.7 KFM80517.1 - 0.00024 21.3 1.3 0.00024 21.3 1.3 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Glyco_hydro_31 PF01055.26 KFM80519.1 - 3.8e-12 46.1 0.0 4.2e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_31 PF01055.26 KFM80520.1 - 2.4e-65 221.5 0.0 2.7e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFM80521.1 - 1.5e-11 44.5 0.1 2.5e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFM80521.1 - 8.6e-06 26.0 0.1 1.9e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Galactose mutarotase-like RPAP3_C PF13877.6 KFM80522.1 - 4e-14 52.9 0.0 5.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 FtsJ PF01728.19 KFM80523.1 - 6.1e-31 107.9 0.0 7.7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase LUC7 PF03194.15 KFM80525.1 - 2.3e-70 237.1 18.7 2.3e-70 237.1 18.7 1.7 1 1 1 2 2 2 1 LUC7 N_terminus La PF05383.17 KFM80526.1 - 7.9e-20 70.7 0.1 1.7e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 KFM80526.1 - 5.8e-18 64.8 0.4 5.8e-18 64.8 0.4 3.3 2 1 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 KFM80526.1 - 5.9e-12 45.2 1.4 2.5e-09 36.8 0.4 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C2 PF00648.21 KFM80527.1 - 1.4e-87 293.5 3.0 3.4e-87 292.2 0.0 2.1 1 1 1 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 KFM80527.1 - 2.8e-29 102.2 0.3 6.3e-29 101.0 0.1 1.7 2 0 0 2 2 2 1 Calpain large subunit, domain III Guanylate_kin PF00625.21 KFM80529.1 - 2.9e-51 173.7 0.7 9.8e-51 172.0 0.1 1.9 2 0 0 2 2 2 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 KFM80529.1 - 6.2e-23 80.6 6.0 1.6e-22 79.3 6.0 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.28 KFM80529.1 - 0.05 13.2 0.3 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 SH3 domain MoCF_biosynth PF00994.24 KFM80532.1 - 1.5e-25 89.6 0.0 1.9e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain SOGA PF11365.8 KFM80533.1 - 0.014 16.6 3.6 0.014 16.6 3.6 2.6 1 1 1 2 2 2 0 Protein SOGA KxDL PF10241.9 KFM80533.1 - 0.022 15.0 3.4 0.022 15.0 3.4 2.8 2 2 1 3 3 3 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 KFM80533.1 - 0.43 11.2 12.9 0.14 12.7 4.1 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.19 KFM80534.1 - 1.5 6.7 12.3 1.7 6.4 12.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF641 PF04859.12 KFM80534.1 - 5.4 7.4 15.0 0.45 10.8 3.2 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ISG65-75 PF11727.8 KFM80535.1 - 0.11 11.7 7.6 0.16 11.2 7.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DYW_deaminase PF14432.6 KFM80535.1 - 0.16 11.8 3.3 2.3 8.1 2.7 2.2 1 1 1 2 2 2 0 DYW family of nucleic acid deaminases Spectrin PF00435.21 KFM80535.1 - 0.19 12.2 8.5 0.062 13.8 2.6 2.4 2 1 0 2 2 2 0 Spectrin repeat FOXP-CC PF16159.5 KFM80535.1 - 0.28 11.9 1.7 0.91 10.2 1.7 1.9 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF1664 PF07889.12 KFM80535.1 - 2.6 8.1 12.7 0.15 12.1 5.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3906 PF13046.6 KFM80536.1 - 0.027 14.6 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) adh_short PF00106.25 KFM80538.1 - 3.1e-50 170.3 0.0 4e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM80538.1 - 1.3e-28 100.1 0.0 1.8e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM80538.1 - 3.5e-15 56.4 0.1 8.8e-15 55.1 0.0 1.6 2 0 0 2 2 2 1 KR domain DFP PF04127.15 KFM80538.1 - 0.0044 16.9 0.1 0.0076 16.1 0.1 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.26 KFM80538.1 - 0.0097 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 KFM80538.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFM80538.1 - 0.035 13.6 0.1 0.074 12.5 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TMEM132D_C PF15706.5 KFM80538.1 - 0.073 12.9 0.2 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term AlaDh_PNT_C PF01262.21 KFM80538.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KFM80538.1 - 0.11 13.1 0.1 0.22 12.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Neuralized PF07177.12 KFM80539.1 - 6.8e-76 253.4 0.1 6.1e-45 152.9 0.1 2.0 2 0 0 2 2 2 2 Neuralized SPRY PF00622.28 KFM80539.1 - 3.5e-05 23.9 0.0 0.0019 18.3 0.0 2.3 2 0 0 2 2 2 1 SPRY domain Neuralized PF07177.12 KFM80540.1 - 1e-25 90.5 0.0 3e-22 79.2 0.1 2.3 2 0 0 2 2 2 2 Neuralized SPRY PF00622.28 KFM80540.1 - 0.0021 18.2 0.0 0.0033 17.6 0.0 1.2 1 0 0 1 1 1 1 SPRY domain 3HCDH PF00725.22 KFM80540.1 - 0.038 14.6 0.0 0.068 13.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Neuralized PF07177.12 KFM80541.1 - 4.1e-51 172.9 0.2 1.3e-39 135.6 0.1 2.1 2 0 0 2 2 2 2 Neuralized VHS PF00790.19 KFM80543.1 - 4e-47 159.6 0.0 6.5e-47 158.9 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KFM80543.1 - 7.5e-24 83.8 2.5 3.1e-23 81.8 0.3 2.8 3 0 0 3 3 3 1 GAT domain ENTH PF01417.20 KFM80543.1 - 1.1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 ENTH domain Vac_ImportDeg PF09783.9 KFM80544.1 - 2e-58 196.8 7.0 2.2e-58 196.6 7.0 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Nop53 PF07767.11 KFM80547.1 - 0.0025 17.3 3.0 0.0025 17.3 3.0 1.4 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) betaPIX_CC PF16523.5 KFM80547.1 - 0.029 14.2 2.8 0.051 13.4 2.8 1.4 1 0 0 1 1 1 0 betaPIX coiled coil MbeD_MobD PF04899.12 KFM80547.1 - 0.034 14.3 4.3 0.054 13.6 4.3 1.3 1 0 0 1 1 1 0 MbeD/MobD like PHD PF00628.29 KFM80550.1 - 1.6e-12 47.1 10.1 2.6e-12 46.4 10.1 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFM80550.1 - 0.00026 21.2 0.5 0.00026 21.2 0.5 1.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFM80550.1 - 0.0071 16.5 0.6 0.01 16.0 0.6 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD_2 PF13831.6 KFM80550.1 - 0.0085 15.6 5.8 0.0085 15.6 5.8 2.3 2 1 0 2 2 2 1 PHD-finger zf-RanBP PF00641.18 KFM80550.1 - 0.11 11.8 1.0 0.11 11.8 1.0 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Prok-RING_1 PF14446.6 KFM80550.1 - 2.7 8.0 12.9 1 9.3 8.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHF12_MRG_bd PF16737.5 KFM80551.1 - 1.8e-16 59.5 0.1 2.4e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain FHA PF00498.26 KFM80552.1 - 0.0059 16.9 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 FHA domain DUF1581 PF07619.11 KFM80553.1 - 0.055 13.6 0.1 0.056 13.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) Syja_N PF02383.18 KFM80554.1 - 1.1e-90 304.3 0.3 1.4e-90 303.9 0.3 1.1 1 0 0 1 1 1 1 SacI homology domain GCIP PF13324.6 KFM80555.1 - 1.3e-53 182.3 0.1 1.9e-53 181.8 0.1 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting INTS5_N PF14837.6 KFM80555.1 - 0.0054 16.4 0.2 0.0087 15.7 0.2 1.4 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus Mrr_N PF14338.6 KFM80555.1 - 0.018 15.1 0.1 0.091 12.9 0.0 2.1 3 0 0 3 3 3 0 Mrr N-terminal domain TED_complement PF07678.14 KFM80556.1 - 5.1e-91 305.0 0.1 7e-91 304.5 0.1 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFM80556.1 - 2.2e-24 86.4 0.4 6.9e-24 84.8 0.4 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFM80556.1 - 1.4e-23 82.6 0.1 3.7e-23 81.2 0.1 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFM80556.1 - 5.4e-23 81.5 0.4 1.6e-22 80.0 0.4 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG4 PF17789.1 KFM80556.1 - 5.4e-05 23.3 0.1 0.0082 16.3 0.0 3.2 2 0 0 2 2 2 1 Macroglobulin domain MG4 SQHop_cyclase_C PF13243.6 KFM80556.1 - 0.049 12.7 0.1 0.27 10.3 0.1 2.0 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain MG3 PF17791.1 KFM80556.1 - 0.092 13.0 0.0 0.33 11.3 0.0 2.0 1 0 0 1 1 1 0 Macroglobulin domain MG3 Focal_AT PF03623.13 KFM80558.1 - 0.026 14.5 0.5 0.031 14.3 0.5 1.1 1 0 0 1 1 1 0 Focal adhesion targeting region DUF1456 PF07308.13 KFM80558.1 - 0.089 13.1 0.1 0.13 12.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) WD40 PF00400.32 KFM80559.1 - 1.3e-42 142.9 17.2 1e-06 29.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM80559.1 - 1e-14 54.6 0.0 0.0024 18.1 0.0 5.4 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM80559.1 - 0.00025 20.5 0.0 0.035 13.4 0.0 2.9 1 1 1 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KFM80559.1 - 0.0014 17.7 0.5 7.5 5.4 0.1 4.1 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFM80559.1 - 0.066 11.7 0.0 0.24 9.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain MCM PF00493.23 KFM80560.1 - 3.3e-100 333.8 0.0 4.7e-100 333.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFM80560.1 - 1.5e-38 131.5 2.5 2.6e-38 130.7 2.5 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFM80560.1 - 2.4e-30 104.8 0.4 8.1e-30 103.1 0.4 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KFM80560.1 - 1.6e-20 73.6 0.7 4e-20 72.4 0.7 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFM80560.1 - 1.2e-06 28.1 0.0 0.00045 19.7 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFM80560.1 - 0.00015 21.8 0.0 0.00051 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFM80560.1 - 0.0075 16.1 0.0 0.029 14.2 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM80560.1 - 0.039 13.7 0.0 0.55 9.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain UFD1 PF03152.14 KFM80561.1 - 2.6e-09 36.8 0.0 2.9e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 UFD1 PF03152.14 KFM80562.1 - 4.6e-59 198.8 0.0 5.7e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 2OG-FeII_Oxy_3 PF13640.6 KFM80564.1 - 2.4e-20 73.2 0.0 4.9e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KFM80564.1 - 2.7e-11 44.0 0.0 5.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 KFM80564.1 - 4.4e-09 36.3 10.9 4.4e-09 36.3 10.9 1.9 2 0 0 2 2 2 1 MYND finger GPAT_N PF14829.6 KFM80566.1 - 0.061 13.3 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Tubulin-binding PF00418.19 KFM80567.1 - 4e-58 193.1 26.7 2.6e-16 59.3 4.9 5.3 5 0 0 5 5 5 5 Tau and MAP protein, tubulin-binding repeat Ras PF00071.22 KFM80570.1 - 3.9e-49 166.4 0.0 4.6e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM80570.1 - 6.9e-30 103.7 0.0 1.5e-29 102.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM80570.1 - 1.4e-10 40.9 0.0 1.8e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KFM80570.1 - 6.4e-05 23.3 0.1 0.00033 21.0 0.1 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 KFM80570.1 - 0.00023 21.2 0.0 0.00043 20.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFM80570.1 - 0.0031 17.1 0.4 0.021 14.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KFM80570.1 - 0.0078 15.9 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 KFM80570.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KFM80570.1 - 0.033 13.7 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ArgoMid PF16487.5 KFM80570.1 - 0.041 14.1 0.1 0.09 13.0 0.1 1.6 1 1 0 1 1 1 0 Mid domain of argonaute RsgA_GTPase PF03193.16 KFM80570.1 - 0.05 13.5 0.1 7.6 6.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KFM80570.1 - 0.055 13.9 0.1 0.11 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.12 KFM80570.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.6 KFM80570.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFM80570.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 KFM80570.1 - 0.16 12.0 0.1 0.38 10.8 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 KFM80570.1 - 0.45 9.6 1.5 10 5.1 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit Syntaxin PF00804.25 KFM80571.1 - 2.6e-56 190.5 18.2 3.4e-56 190.1 18.2 1.1 1 0 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 KFM80571.1 - 2e-09 37.7 8.6 2e-09 37.7 8.6 1.8 2 0 0 2 2 2 1 Syntaxin-like protein Med10 PF09748.9 KFM80571.1 - 0.012 15.6 4.6 0.092 12.7 4.5 2.2 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex LOH1CR12 PF10158.9 KFM80571.1 - 0.019 15.0 2.8 0.019 15.0 2.8 2.2 2 0 0 2 2 2 0 Tumour suppressor protein COG5 PF10392.9 KFM80571.1 - 0.024 14.8 6.9 0.097 12.8 3.2 2.6 2 2 0 2 2 2 0 Golgi transport complex subunit 5 Lzipper-MIP1 PF14389.6 KFM80571.1 - 0.093 13.0 0.5 0.093 13.0 0.5 2.9 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Uso1_p115_C PF04871.13 KFM80571.1 - 0.14 12.5 11.9 1.1 9.6 6.0 2.7 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Acyl-CoA_dh_2 PF08028.11 KFM80571.1 - 0.23 11.8 2.0 0.3 11.4 0.2 2.1 2 1 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Baculo_PEP_C PF04513.12 KFM80571.1 - 0.23 11.5 7.8 2.8 8.0 1.3 2.7 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBCC_N PF16752.5 KFM80571.1 - 0.27 11.7 11.3 4.4 7.8 4.9 3.2 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Apolipoprotein PF01442.18 KFM80571.1 - 0.28 11.0 9.6 0.35 10.7 5.8 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Mod_r PF07200.13 KFM80571.1 - 0.3 11.2 13.3 0.31 11.1 8.7 2.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Allexi_40kDa PF05549.11 KFM80571.1 - 0.42 10.1 8.0 0.17 11.4 3.7 2.0 1 1 0 2 2 2 0 Allexivirus 40kDa protein HAUS6_N PF14661.6 KFM80571.1 - 0.65 9.5 9.9 1.5 8.3 9.9 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3347 PF11827.8 KFM80571.1 - 0.76 9.9 6.6 0.26 11.4 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) OmpH PF03938.14 KFM80571.1 - 0.88 9.9 12.6 2 8.7 8.6 2.6 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 KFM80571.1 - 0.93 10.1 12.7 0.94 10.1 0.1 3.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.11 KFM80571.1 - 1.3 9.3 6.1 4.9 7.5 2.7 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KFM80571.1 - 2 9.0 10.3 33 5.0 0.6 4.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein PCRF PF03462.18 KFM80571.1 - 3.6 7.4 11.4 2.6 7.9 3.1 2.3 1 1 1 2 2 2 0 PCRF domain Seryl_tRNA_N PF02403.22 KFM80571.1 - 7.4 6.9 18.6 3.5 7.9 9.4 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SNARE PF05739.19 KFM80572.1 - 2.6e-19 69.0 2.9 3.1e-19 68.7 2.9 1.2 1 0 0 1 1 1 1 SNARE domain T2SSF PF00482.23 KFM80572.1 - 0.00026 21.0 0.2 0.00027 20.9 0.2 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F ETRAMP PF09716.10 KFM80572.1 - 0.00075 19.5 0.6 0.00081 19.4 0.6 1.1 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF3671 PF12420.8 KFM80572.1 - 0.0013 18.8 0.2 0.0013 18.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function TRIQK PF15168.6 KFM80572.1 - 0.0054 16.6 0.7 0.0057 16.5 0.7 1.1 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family Prominin PF05478.11 KFM80572.1 - 0.0057 14.7 0.5 0.0064 14.5 0.5 1.0 1 0 0 1 1 1 1 Prominin Synaptobrevin PF00957.21 KFM80572.1 - 0.0072 16.1 0.5 0.0077 16.0 0.5 1.1 1 0 0 1 1 1 1 Synaptobrevin Herpes_US9 PF06072.11 KFM80572.1 - 0.012 15.5 0.2 0.014 15.2 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 TssN PF17555.2 KFM80572.1 - 0.019 14.4 1.0 0.023 14.1 1.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Pox_EPC_I2-L1 PF12575.8 KFM80572.1 - 0.032 14.4 0.2 0.034 14.4 0.2 1.1 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 BIV_Env PF05858.12 KFM80572.1 - 0.033 12.4 0.4 0.036 12.3 0.4 1.0 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Fusion_gly PF00523.18 KFM80572.1 - 0.036 12.3 1.6 0.038 12.2 1.6 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF2207 PF09972.9 KFM80572.1 - 0.04 12.7 0.2 0.045 12.5 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3377 PF11857.8 KFM80572.1 - 0.043 13.7 0.4 0.044 13.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) EssA PF10661.9 KFM80572.1 - 0.044 13.6 0.3 0.048 13.5 0.3 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA ZapA PF05164.13 KFM80572.1 - 0.056 13.9 0.1 0.06 13.8 0.1 1.1 1 0 0 1 1 1 0 Cell division protein ZapA TMEM154 PF15102.6 KFM80572.1 - 0.12 12.2 0.5 0.13 12.2 0.5 1.1 1 0 0 1 1 1 0 TMEM154 protein family Tmemb_9 PF05434.11 KFM80572.1 - 0.16 11.9 0.6 0.15 12.0 0.6 1.1 1 0 0 1 1 1 0 TMEM9 DUF2116 PF09889.9 KFM80572.1 - 0.28 11.2 1.9 0.35 10.9 1.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3139 PF11337.8 KFM80572.1 - 1.2 9.8 7.5 2 9.1 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) EpuA PF11772.8 KFM80572.1 - 7.4 6.4 14.4 9.6 6.0 14.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta 4HB_MCP_1 PF12729.7 KFM80572.1 - 7.8 6.0 11.1 6.8 6.2 9.7 1.5 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction CIMR PF00878.18 KFM80575.1 - 1.2e-06 28.6 0.1 1.8e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat DUP PF00674.18 KFM80575.1 - 0.089 12.9 0.4 0.91 9.7 0.0 2.1 2 0 0 2 2 2 0 DUP family CIMR PF00878.18 KFM80576.1 - 1.3e-145 479.2 50.5 6e-28 97.7 0.6 8.0 8 0 0 8 8 8 8 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KFM80576.1 - 1.7e-35 123.2 35.3 2.2e-09 37.6 0.2 8.6 2 2 5 7 7 7 7 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KFM80576.1 - 1.8e-26 92.8 9.1 8.8e-05 21.7 0.0 7.1 5 2 2 7 7 7 6 Mannose-6-phosphate receptor PRKCSH_1 PF13015.6 KFM80576.1 - 3.5e-15 56.0 8.8 6e-07 29.3 0.1 5.3 6 0 0 6 6 6 3 Glucosidase II beta subunit-like protein BRICHOS PF04089.14 KFM80577.1 - 0.031 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 BRICHOS domain RNA_pol_A_bac PF01000.26 KFM80578.1 - 3.8e-38 130.3 0.2 6.3e-38 129.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFM80578.1 - 2.7e-18 65.2 0.0 3.8e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Metallophos PF00149.28 KFM80579.1 - 1e-09 39.2 0.1 1.4e-09 38.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM80579.1 - 0.0051 17.0 0.0 0.023 14.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mre11_DNA_bind PF04152.14 KFM80580.1 - 1.7e-42 145.7 2.0 1.7e-42 145.7 2.0 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain VIT1 PF01988.19 KFM80580.1 - 0.013 15.3 0.3 0.031 14.2 0.3 1.5 1 0 0 1 1 1 0 VIT family DUF5624 PF18538.1 KFM80580.1 - 0.1 12.7 0.8 1.2 9.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Ribosomal_L6 PF00347.23 KFM80581.1 - 4.8e-31 107.3 4.5 3e-18 66.3 1.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DDE_Tnp_1_7 PF13843.6 KFM80582.1 - 2.3e-08 33.7 0.2 3.2e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM80582.1 - 0.0011 19.7 6.7 0.0011 19.7 6.7 2.0 2 0 0 2 2 2 1 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.16 KFM80582.1 - 0.023 15.0 0.6 0.037 14.3 0.6 1.4 1 0 0 1 1 1 0 C1 domain C1_1 PF00130.22 KFM80582.1 - 0.042 13.7 2.2 0.071 13.0 2.2 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glycos_transf_2 PF00535.26 KFM80583.1 - 1e-20 74.2 0.0 1.5e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFM80583.1 - 9.8e-05 22.3 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFM80583.1 - 0.00044 19.8 0.3 0.0015 18.1 0.3 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KFM80583.1 - 0.029 14.9 0.0 0.096 13.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KFM80583.1 - 0.056 13.4 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 LRR_8 PF13855.6 KFM80584.1 - 1.8e-43 146.1 30.6 3.6e-14 52.3 1.9 5.8 3 1 3 7 7 7 5 Leucine rich repeat LRR_5 PF13306.6 KFM80584.1 - 8.6e-22 77.5 2.1 1.6e-11 44.3 0.2 3.9 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM80584.1 - 1.1e-15 57.5 30.9 9.1e-06 25.9 0.9 6.6 5 1 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM80584.1 - 3.1e-09 36.6 15.6 0.00077 19.0 1.7 3.5 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFM80584.1 - 3.9e-05 23.6 16.6 11 7.0 0.0 8.7 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 KFM80584.1 - 0.14 12.3 12.3 6.5 7.1 0.1 6.8 8 0 0 8 8 8 0 Leucine Rich repeat DUF4315 PF14193.6 KFM80584.1 - 0.2 11.7 3.3 0.26 11.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) LRR_12 PF18837.1 KFM80584.1 - 0.98 9.1 4.0 5 6.9 0.2 3.2 2 1 1 3 3 3 0 Leucine-rich repeat Ras PF00071.22 KFM80586.1 - 3.3e-27 95.1 0.0 4.9e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM80586.1 - 2e-13 50.6 0.0 3.4e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM80586.1 - 7.5e-08 32.0 0.0 2.1e-06 27.3 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 KFM80587.1 - 3.6e-29 101.5 1.6 5.3e-29 100.9 1.6 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM80587.1 - 2.1e-16 60.2 0.5 3.5e-16 59.5 0.5 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM80587.1 - 9.7e-09 34.9 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM80587.1 - 0.00068 19.7 0.2 0.0012 18.9 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Torsin PF06309.11 KFM80587.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_7 PF12775.7 KFM80587.1 - 0.035 13.6 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF1133 PF06576.11 KFM80587.1 - 0.04 13.3 0.1 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1133) SRPRB PF09439.10 KFM80587.1 - 0.052 13.0 0.2 0.2 11.1 0.2 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MCM PF00493.23 KFM80590.1 - 5.5e-101 336.3 0.0 1.9e-100 334.6 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KFM80590.1 - 1.1e-35 122.2 0.7 2.3e-35 121.2 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFM80590.1 - 2.5e-23 82.3 0.2 7.2e-23 80.8 0.2 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFM80590.1 - 6.5e-19 68.5 2.0 1.8e-18 67.0 2.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFM80590.1 - 1.9e-08 34.0 0.1 1.8e-05 24.2 0.0 3.2 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFM80590.1 - 6.3e-08 32.7 0.0 2.8e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_bind PF09739.9 KFM80590.1 - 0.01 14.4 0.0 0.023 13.1 0.0 1.5 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA_3 PF07726.11 KFM80590.1 - 0.022 14.6 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KFM80590.1 - 0.028 14.3 0.6 0.17 11.8 0.1 2.4 2 0 0 2 2 2 0 AAA lid domain Sigma54_activat PF00158.26 KFM80590.1 - 0.058 13.1 0.0 0.22 11.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 KFM80590.1 - 3 8.5 4.8 1.7 9.3 0.2 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Ig_3 PF13927.6 KFM80592.1 - 2.5e-19 69.6 0.1 1.4e-10 41.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM80592.1 - 3.2e-14 52.8 0.2 1.6e-10 40.9 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM80592.1 - 4.1e-12 46.3 0.1 2.4e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM80592.1 - 2e-08 34.3 0.2 0.00015 21.9 0.0 2.7 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFM80592.1 - 0.003 17.7 0.6 0.98 9.6 0.1 3.5 3 1 0 4 4 4 1 Immunoglobulin V-set domain fn3 PF00041.21 KFM80592.1 - 0.014 15.7 0.1 0.035 14.5 0.0 1.7 2 0 0 2 2 2 0 Fibronectin type III domain Ig_6 PF18452.1 KFM80592.1 - 0.022 14.3 0.2 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain PKD PF00801.20 KFM80592.1 - 0.13 12.1 0.1 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 PKD domain C2-set_2 PF08205.12 KFM80593.1 - 1.5e-07 31.4 0.1 2.9e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM80593.1 - 0.00018 22.1 0.3 0.0015 19.1 0.0 2.0 1 1 1 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFM80593.1 - 0.066 13.3 0.1 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin I-set domain tRNA-synt_1d PF00750.19 KFM80597.1 - 6.5e-145 482.4 0.1 1.3e-144 481.4 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KFM80597.1 - 7.7e-29 100.3 0.3 2.7e-28 98.5 0.3 2.0 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KFM80597.1 - 1.6e-18 67.1 0.0 5.7e-18 65.3 0.0 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 KFM80597.1 - 0.0036 16.7 0.0 0.0082 15.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain SBP_bac_5 PF00496.22 KFM80597.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle tRNA-synt_1 PF00133.22 KFM80597.1 - 0.019 13.2 0.0 0.035 12.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) HSR PF03172.13 KFM80597.1 - 0.023 14.8 0.6 1.5 9.0 0.0 2.9 2 0 0 2 2 2 0 HSR domain NOG1_N PF17835.1 KFM80597.1 - 0.026 14.5 4.8 0.048 13.6 0.8 2.9 2 1 0 2 2 2 0 NOG1 N-terminal helical domain YabA PF06156.13 KFM80597.1 - 0.18 12.5 2.7 0.56 10.9 0.9 2.6 2 0 0 2 2 2 0 Initiation control protein YabA SUB1_ProdP9 PF18213.1 KFM80597.1 - 2.4 8.0 5.0 1.7 8.6 0.1 3.2 4 0 0 4 4 4 0 SUB1 protease Prodomain ProdP9 Pkinase PF00069.25 KFM80599.1 - 1.5e-08 34.4 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1963 PF09234.10 KFM80599.1 - 0.033 14.7 0.1 0.04 14.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) Pkinase_Tyr PF07714.17 KFM80599.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KFM80600.1 - 1.4e-69 234.4 0.0 1.7e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM80600.1 - 2e-36 125.6 0.0 2.4e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM80600.1 - 1.2e-05 24.4 0.1 1.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM80600.1 - 8.1e-05 22.1 0.0 0.0084 15.5 0.0 2.2 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KFM80600.1 - 0.001 18.7 0.1 0.0014 18.2 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 KFM80600.1 - 0.0016 17.6 0.2 0.003 16.7 0.1 1.3 1 1 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KFM80600.1 - 0.0079 15.6 0.6 0.016 14.6 0.6 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM80600.1 - 0.022 14.7 0.0 0.058 13.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family CNH PF00780.22 KFM80601.1 - 5.4e-54 183.6 0.1 6.7e-54 183.3 0.1 1.1 1 0 0 1 1 1 1 CNH domain HIT PF01230.23 KFM80602.1 - 4.4e-30 104.3 0.0 5.1e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFM80602.1 - 1.8e-23 83.2 0.0 2.2e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GNT-I PF03071.15 KFM80603.1 - 3.5e-53 180.9 1.2 1.8e-52 178.6 1.2 1.8 1 1 0 1 1 1 1 GNT-I family ILEI PF15711.5 KFM80603.1 - 1.7e-24 86.1 0.0 3.5e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Interleukin-like EMT inducer MGAT2 PF05060.14 KFM80603.1 - 0.004 16.3 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) RTC PF01137.21 KFM80604.1 - 1.1e-84 283.1 0.1 1.3e-84 282.9 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KFM80604.1 - 7.5e-24 84.2 0.3 1.4e-23 83.4 0.3 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain vATP-synt_E PF01991.18 KFM80605.1 - 5.7e-40 136.9 2.3 6.5e-40 136.7 2.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4899 PF16240.5 KFM80605.1 - 0.0018 17.5 1.4 0.0025 17.1 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4899) PIN_12 PF16289.5 KFM80605.1 - 0.023 15.2 2.4 0.034 14.6 2.4 1.2 1 0 0 1 1 1 0 PIN domain HrpE PF06188.12 KFM80605.1 - 0.048 13.5 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Cation_ATPase_C PF00689.21 KFM80606.1 - 4.7e-45 153.5 0.1 4.7e-45 153.5 0.1 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFM80606.1 - 1.4e-44 151.8 0.7 1.4e-44 151.8 0.7 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFM80606.1 - 5.6e-22 77.6 0.0 1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFM80606.1 - 1.6e-21 77.6 0.0 5.7e-12 46.4 0.0 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM80606.1 - 1.3e-06 28.3 1.5 0.00069 19.4 0.5 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM80606.1 - 0.0083 16.6 0.1 0.059 13.8 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sigma70_r4 PF04545.16 KFM80606.1 - 0.074 12.6 0.0 0.21 11.1 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 Peripla_BP_4 PF13407.6 KFM80606.1 - 1.8 8.0 5.0 28 4.1 5.0 2.2 1 1 0 1 1 1 0 Periplasmic binding protein domain RAI1 PF08652.11 KFM80607.1 - 1.3e-19 70.1 0.1 2.3e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease PK PF00224.21 KFM80608.1 - 1.7e-163 543.5 6.5 2.2e-163 543.1 6.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFM80608.1 - 6.2e-35 120.0 1.3 1.9e-34 118.4 1.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFM80608.1 - 0.0036 16.5 0.6 0.011 14.9 0.5 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DUF1449 PF07290.11 KFM80608.1 - 0.077 12.6 2.2 0.17 11.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) Viral_P18 PF04521.13 KFM80608.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Aminotran_5 PF00266.19 KFM80609.1 - 5e-53 180.4 0.0 5.7e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Anoctamin PF04547.12 KFM80610.1 - 4.9e-156 520.1 18.2 6.4e-156 519.7 18.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFM80610.1 - 7.2e-62 209.1 0.0 1.1e-61 208.5 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Bclx_interact PF08945.10 KFM80610.1 - 0.15 11.8 0.1 0.41 10.5 0.1 1.7 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Polyketide_cyc PF03364.20 KFM80611.1 - 1e-16 61.3 0.0 1.1e-16 61.3 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PITH PF06201.13 KFM80612.1 - 1.7e-45 155.0 0.0 1.9e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 PITH domain Pkinase PF00069.25 KFM80614.1 - 8.1e-08 32.0 0.3 1.1e-07 31.5 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM80614.1 - 0.00059 19.2 0.1 0.00083 18.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 KFM80614.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.25 KFM80615.1 - 6.5e-12 45.4 0.0 9.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kelch_2 PF07646.15 KFM80615.1 - 0.057 13.4 0.1 0.1 12.6 0.1 1.6 1 1 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 KFM80615.1 - 0.1 12.6 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Galactose oxidase, central domain fn3 PF00041.21 KFM80616.1 - 6.4e-05 23.2 0.1 8.9e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Fibronectin type III domain Tom22 PF04281.13 KFM80617.1 - 0.11 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Toxin_35 PF10530.9 KFM80618.1 - 3.9e-05 23.6 9.6 3.9e-05 23.6 9.6 1.9 2 0 0 2 2 2 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Toxin_35 PF10530.9 KFM80620.1 - 1.2e-05 25.2 11.2 1.6e-05 24.8 11.2 1.2 1 0 0 1 1 1 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold MARVEL PF01284.23 KFM80621.1 - 3.8e-07 30.2 11.8 6.9e-07 29.4 11.8 1.5 1 0 0 1 1 1 1 Membrane-associating domain UCR_14kD PF02271.16 KFM80622.1 - 6.3e-36 122.4 0.7 7.2e-36 122.2 0.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit N1221 PF07923.13 KFM80622.1 - 0.009 15.2 0.3 0.0091 15.2 0.3 1.1 1 0 0 1 1 1 1 N1221-like protein Intein_splicing PF14890.6 KFM80622.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.3 1 1 0 1 1 1 0 Intein splicing domain Phage_holin_3_6 PF07332.11 KFM80623.1 - 0.14 12.2 0.4 0.16 12.0 0.4 1.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LMWPc PF01451.21 KFM80627.1 - 9.1e-21 74.7 0.0 9.9e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Tnp_P_element PF12017.8 KFM80628.1 - 0.04 13.3 0.0 0.045 13.2 0.0 1.0 1 0 0 1 1 1 0 Transposase protein zf-RING_2 PF13639.6 KFM80629.1 - 1.3e-10 41.5 29.9 7.9e-09 35.7 5.9 3.0 2 0 0 2 2 2 2 Ring finger domain PHD PF00628.29 KFM80629.1 - 5.2e-07 29.5 15.2 5.2e-07 29.5 15.2 3.5 3 0 0 3 3 3 1 PHD-finger zf-C3HC4 PF00097.25 KFM80629.1 - 2e-05 24.3 6.7 2e-05 24.3 6.7 2.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM80629.1 - 7.5e-05 22.5 3.2 7.5e-05 22.5 3.2 2.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM80629.1 - 0.00017 21.6 5.3 0.00017 21.6 5.3 2.7 2 0 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM80629.1 - 0.0002 21.1 3.9 0.0002 21.1 3.9 3.0 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFM80629.1 - 0.00021 21.1 6.8 0.00021 21.1 6.8 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM80629.1 - 0.0021 18.3 6.9 0.0021 18.3 6.9 3.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM80629.1 - 0.0034 17.3 5.0 0.0034 17.3 5.0 2.7 2 0 0 2 2 1 1 zinc-RING finger domain Zf_RING PF16744.5 KFM80629.1 - 1.3 9.1 14.1 0.17 12.0 4.0 2.9 2 0 0 2 2 2 0 KIAA1045 RING finger zf-ANAPC11 PF12861.7 KFM80629.1 - 1.4 9.0 13.6 3 8.0 1.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Peptidase_M20 PF01546.28 KFM80630.1 - 4.8e-39 134.2 0.0 6.5e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFM80630.1 - 2.7e-15 56.2 0.0 5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFM80630.1 - 0.0076 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 FMN_red PF03358.15 KFM80630.1 - 0.017 14.9 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 0 NADPH-dependent FMN reductase CDP-OH_P_transf PF01066.21 KFM80631.1 - 1.3e-08 35.4 0.1 1.3e-08 35.4 0.1 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HCO3_cotransp PF00955.21 KFM80632.1 - 1.1e-229 763.5 9.1 1.4e-229 763.1 9.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFM80632.1 - 5.3e-102 341.2 0.0 5.3e-102 341.2 0.0 2.1 3 0 0 3 3 3 1 Band 3 cytoplasmic domain Sensor PF13796.6 KFM80632.1 - 2.4 8.2 8.6 5.3 7.1 0.0 3.4 2 1 0 3 3 3 0 Putative sensor LRR_4 PF12799.7 KFM80633.1 - 1.3e-13 50.9 28.3 0.00038 20.8 0.1 9.2 4 4 6 10 10 10 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM80633.1 - 1.8e-12 46.2 15.3 0.023 14.7 0.0 9.6 10 0 0 10 10 10 5 Leucine Rich repeat F-box PF00646.33 KFM80633.1 - 1.8e-10 40.4 0.2 5.9e-10 38.8 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFM80633.1 - 3.5e-09 36.4 0.2 8.5e-09 35.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KFM80633.1 - 3.9e-08 32.7 0.1 9.6e-08 31.5 0.1 1.7 1 0 0 1 1 1 1 F-box LRR_1 PF00560.33 KFM80633.1 - 7.5e-08 31.9 21.1 6.8 7.7 0.0 10.0 10 2 0 10 10 10 3 Leucine Rich Repeat LRR_8 PF13855.6 KFM80633.1 - 2.3e-06 27.2 14.5 1.1 9.1 0.4 6.8 5 1 2 7 7 7 5 Leucine rich repeat Ras PF00071.22 KFM80634.1 - 1e-62 210.5 0.1 1.3e-62 210.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM80634.1 - 1.8e-33 115.3 0.1 4.4e-33 114.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM80634.1 - 1.1e-12 47.7 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM80634.1 - 5.1e-05 23.3 0.0 8e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM80634.1 - 0.00019 20.8 0.0 0.00027 20.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM80634.1 - 0.00049 19.7 0.2 0.0023 17.5 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM80634.1 - 0.00058 19.8 0.1 0.29 11.0 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFM80634.1 - 0.033 14.4 0.1 0.22 11.8 0.1 2.3 1 1 1 2 2 2 0 AAA domain DAP3 PF10236.9 KFM80634.1 - 0.073 12.2 0.1 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 KFM80634.1 - 0.098 12.4 0.1 0.13 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain Snurportin1 PF11538.8 KFM80636.1 - 5e-15 55.4 4.7 7.4e-15 54.9 4.7 1.3 1 0 0 1 1 1 1 Snurportin1 DUF1027 PF06265.11 KFM80636.1 - 0.058 13.4 0.5 0.1 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) RPEL PF02755.15 KFM80637.1 - 8.5e-16 57.1 13.2 4.3e-09 35.8 3.1 3.7 3 0 0 3 3 3 2 RPEL repeat SAP PF02037.27 KFM80637.1 - 2.2e-11 43.2 1.7 6.7e-11 41.7 0.2 2.3 2 0 0 2 2 2 1 SAP domain Bacillus_HBL PF05791.11 KFM80637.1 - 0.019 14.8 1.0 0.019 14.8 1.0 2.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) V_ATPase_I PF01496.19 KFM80637.1 - 5.2 4.9 9.4 9.4 4.0 9.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_RNA_pol PF03293.14 KFM80639.1 - 0.061 13.0 0.1 0.089 12.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Cytochrom_B561 PF03188.16 KFM80641.1 - 8.2e-35 119.9 12.9 8.2e-35 119.9 12.9 1.8 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Bestrophin PF01062.21 KFM80641.1 - 0.19 11.1 3.0 1.6 8.1 1.2 2.1 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel DUF4079 PF13301.6 KFM80641.1 - 1.4 9.1 11.8 36 4.5 9.9 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 KFM80641.1 - 1.8 8.1 19.0 0.039 13.5 6.8 2.8 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 BRO1 PF03097.18 KFM80642.1 - 1.6e-88 297.2 3.7 1.6e-88 297.2 3.7 1.4 2 0 0 2 2 2 1 BRO1-like domain HR1 PF02185.16 KFM80642.1 - 4e-14 52.5 5.7 4e-14 52.5 5.7 2.2 2 0 0 2 2 2 1 Hr1 repeat PDZ PF00595.24 KFM80642.1 - 8.1e-12 45.3 0.1 1.7e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM80642.1 - 1.1e-09 38.0 0.4 3.9e-09 36.2 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFM80642.1 - 0.00062 20.0 0.1 0.0015 18.8 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFM80642.1 - 0.03 14.3 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain TMV_coat PF00721.21 KFM80642.1 - 0.042 13.7 0.3 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Virus coat protein (TMV like) Dicer_dimer PF03368.14 KFM80642.1 - 0.054 13.7 0.2 0.41 10.8 0.2 2.3 2 0 0 2 2 2 0 Dicer dimerisation domain LRR_8 PF13855.6 KFM80643.1 - 6.9e-16 57.8 3.9 4.8e-08 32.6 0.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM80643.1 - 4.4e-08 33.3 8.5 2.3e-05 24.6 0.7 3.9 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) DUF3557 PF12078.8 KFM80643.1 - 0.041 13.8 1.0 0.07 13.1 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3557) LRR_9 PF14580.6 KFM80643.1 - 0.15 11.5 0.7 0.59 9.6 0.5 1.9 1 1 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 KFM80643.1 - 0.32 11.7 3.2 19 6.3 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat DUF3579 PF12112.8 KFM80644.1 - 0.0093 16.5 0.3 0.014 15.9 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3579) KASH_CCD PF14662.6 KFM80644.1 - 0.038 13.8 0.8 0.089 12.6 0.6 1.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CLZ PF16526.5 KFM80644.1 - 0.039 14.3 0.0 0.078 13.3 0.0 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ACP_PD PF04336.12 KFM80644.1 - 0.083 13.3 0.2 0.48 10.9 0.2 1.9 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase zf-H2C2_2 PF13465.6 KFM80647.1 - 1.1e-69 227.9 86.5 2.3e-08 34.1 2.6 13.1 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80647.1 - 1.2e-45 151.5 99.7 1.5e-05 25.1 0.7 12.1 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80647.1 - 1e-32 110.0 95.2 0.0016 19.1 0.3 12.0 12 0 0 12 12 12 10 C2H2-type zinc finger zf-met PF12874.7 KFM80647.1 - 2e-22 78.8 86.6 0.0092 16.3 3.0 12.0 12 0 0 12 12 12 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM80647.1 - 1.6e-13 50.5 63.2 0.042 14.2 0.9 11.5 10 1 1 11 11 11 8 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM80647.1 - 3e-10 39.8 21.6 0.27 11.1 0.6 8.9 2 1 9 11 11 11 5 GAGA factor zf-C2H2_6 PF13912.6 KFM80647.1 - 4.9e-10 39.1 76.9 0.01 15.8 0.6 11.4 12 0 0 12 12 12 7 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM80647.1 - 4.3e-08 32.9 50.7 0.97 9.3 0.4 10.7 4 2 7 11 11 11 7 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM80647.1 - 2.6e-05 24.3 43.6 0.013 15.6 5.2 5.1 1 1 4 5 5 5 5 Putative ribonucleoprotein zinc-finger pf C4 type zf-H2C2_5 PF13909.6 KFM80647.1 - 3.2e-05 23.6 3.6 0.03 14.1 0.0 10.1 11 0 0 11 11 11 4 C2H2-type zinc-finger domain Tox-HNH-HHH PF15637.6 KFM80647.1 - 6.4e-05 23.1 8.0 0.72 10.0 0.0 5.5 1 1 4 6 6 6 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif BolA PF01722.18 KFM80647.1 - 0.00017 21.8 18.0 0.29 11.4 0.1 5.8 2 1 5 7 7 7 2 BolA-like protein C1_1 PF00130.22 KFM80647.1 - 0.00068 19.5 56.7 0.43 10.5 1.0 9.7 4 2 6 10 10 10 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MYST PF17772.1 KFM80647.1 - 0.00092 18.8 45.0 0.19 11.4 0.1 9.4 7 2 3 10 10 10 3 MYST family zinc finger domain DUF2256 PF10013.9 KFM80647.1 - 0.00099 19.2 41.5 10 6.4 0.3 10.2 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.12 KFM80647.1 - 0.0026 17.9 50.3 8.3 6.6 0.6 10.2 11 0 0 11 11 11 0 DBF zinc finger DUF3396 PF11876.8 KFM80647.1 - 0.015 14.8 0.0 0.53 9.7 0.0 3.4 4 2 1 5 5 5 0 Protein of unknown function (DUF3396) zf-FPG_IleRS PF06827.14 KFM80647.1 - 0.036 13.9 30.7 2.6 8.0 0.1 9.5 10 0 0 10 10 10 0 Zinc finger found in FPG and IleRS zf-Sec23_Sec24 PF04810.15 KFM80647.1 - 0.1 12.7 32.4 1.5 9.0 0.1 9.6 8 1 2 10 10 10 0 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM80647.1 - 0.2 11.6 42.1 1.7 8.6 0.2 9.8 11 0 0 11 11 11 0 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM80647.1 - 0.43 10.6 33.0 5.7 7.0 1.5 6.9 4 2 2 6 6 6 0 Adenylate kinase, active site lid TRAF6_Z2 PF18048.1 KFM80647.1 - 0.52 10.4 60.2 0.74 10.0 1.6 10.0 11 0 0 11 11 11 0 TNF receptor-associated factor 6 zinc finger 2 FYVE PF01363.21 KFM80647.1 - 0.99 9.6 58.1 0.55 10.4 9.5 5.7 3 2 3 6 6 6 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFM80647.1 - 1.7 9.0 81.6 2.8 8.3 1.3 10.1 1 1 7 9 9 9 0 C2H2 type zinc-finger (2 copies) Z1 PF10593.9 KFM80647.1 - 5.7 6.4 10.8 4.7 6.7 0.1 3.3 1 1 2 3 3 3 0 Z1 domain Kinesin PF00225.23 KFM80648.1 - 2.3e-05 23.5 0.1 2.3e-05 23.5 0.1 2.3 2 1 0 2 2 2 1 Kinesin motor domain DUF948 PF06103.11 KFM80648.1 - 4.8 7.5 9.2 4.8 7.5 1.0 3.5 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Kinesin PF00225.23 KFM80649.1 - 6.1e-15 55.0 0.0 6.2e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM80649.1 - 8.2e-07 29.1 0.0 9.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding Caprin-1_dimer PF18293.1 KFM80650.1 - 6.1e-24 84.7 0.6 6.1e-24 84.7 0.6 2.3 2 1 0 2 2 2 1 Caprin-1 dimerization domain DUF3435 PF11917.8 KFM80650.1 - 0.013 14.4 3.4 0.015 14.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF4479 PF14794.6 KFM80650.1 - 0.052 13.4 0.8 1.8 8.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) DUF1394 PF07159.12 KFM80650.1 - 0.07 12.4 5.7 0.09 12.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) CDK2AP PF09806.9 KFM80650.1 - 0.53 10.3 5.7 0.6 10.1 3.9 1.7 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein GLTSCR1 PF15249.6 KFM80650.1 - 1.6 9.2 7.5 3.9 8.0 7.5 1.8 1 1 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein Syntaxin_2 PF14523.6 KFM80650.1 - 1.7 9.1 12.0 16 6.0 12.0 2.4 1 1 0 1 1 1 0 Syntaxin-like protein V_ATPase_I PF01496.19 KFM80650.1 - 3.6 5.4 7.7 4 5.2 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PCRF PF03462.18 KFM80650.1 - 7.8 6.3 11.3 4.3 7.1 5.2 2.0 1 1 1 2 2 2 0 PCRF domain DUF4211 PF13926.6 KFM80653.1 - 0.00022 21.3 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Requiem_N PF14051.6 KFM80655.1 - 4.2e-37 126.2 1.4 1.5e-36 124.5 1.4 2.0 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.29 KFM80655.1 - 5.4e-21 74.2 26.4 3.6e-13 49.2 4.5 3.5 3 1 1 4 4 4 2 PHD-finger PHD_4 PF16866.5 KFM80655.1 - 0.00027 21.0 7.7 0.00027 21.0 7.7 3.5 3 1 1 4 4 4 1 PHD-finger zf-PHD-like PF15446.6 KFM80655.1 - 0.0094 15.6 9.4 0.24 11.0 2.2 2.9 1 1 1 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KFM80655.1 - 0.017 15.0 0.5 0.017 15.0 0.5 4.1 4 1 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lar_restr_allev PF14354.6 KFM80655.1 - 0.023 15.1 0.9 0.023 15.1 0.9 4.0 2 1 1 3 3 3 0 Restriction alleviation protein Lar PHD_2 PF13831.6 KFM80655.1 - 0.045 13.3 1.0 0.045 13.3 1.0 3.6 3 1 0 3 3 3 0 PHD-finger zf-C2H2_4 PF13894.6 KFM80655.1 - 0.1 13.5 0.3 0.1 13.5 0.3 5.0 6 1 0 6 6 6 0 C2H2-type zinc finger Prok-RING_1 PF14446.6 KFM80655.1 - 1.4 8.9 21.0 0.67 9.9 0.8 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_7 PF02591.15 KFM80655.1 - 8 6.7 11.0 7.9 6.8 0.1 3.8 3 1 0 3 3 3 0 C4-type zinc ribbon domain Tetraspanin PF00335.20 KFM80657.1 - 1.2e-43 149.5 6.0 1.5e-43 149.2 6.0 1.1 1 0 0 1 1 1 1 Tetraspanin family Wzy_C PF04932.15 KFM80657.1 - 0.0028 17.3 1.0 0.0028 17.3 1.0 1.9 1 1 1 2 2 2 1 O-Antigen ligase DUF3742 PF12553.8 KFM80657.1 - 0.11 12.6 1.6 8 6.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) FA_desaturase PF00487.24 KFM80657.1 - 0.24 11.2 0.9 0.46 10.3 0.9 1.4 1 0 0 1 1 1 0 Fatty acid desaturase UPF0182 PF03699.13 KFM80657.1 - 1.7 6.7 3.8 2.2 6.3 3.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF973 PF06157.11 KFM80657.1 - 2.2 7.3 12.3 3.6 6.5 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Tetraspanin PF00335.20 KFM80658.1 - 9.5e-38 130.2 8.6 1.1e-37 130.0 8.6 1.0 1 0 0 1 1 1 1 Tetraspanin family Cytochrome-c551 PF10643.9 KFM80658.1 - 0.17 11.5 1.0 0.26 10.9 1.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Tachystatin_A PF11406.8 KFM80658.1 - 0.22 11.6 2.2 7.7 6.7 0.2 2.4 2 0 0 2 2 2 0 Antimicrobial peptide tachystatin A DUF2070 PF09843.9 KFM80658.1 - 3.4 5.8 6.6 5.1 5.3 6.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SUR7 PF06687.12 KFM80658.1 - 5.1 6.7 12.5 1.2 8.8 8.8 1.7 1 1 0 1 1 1 0 SUR7/PalI family QVR PF17064.5 KFM80659.1 - 0.0062 16.8 10.0 0.0085 16.3 10.0 1.2 1 0 0 1 1 1 1 Sleepless protein NPP1 PF05630.11 KFM80659.1 - 0.019 15.1 1.3 0.043 13.9 1.1 1.6 1 1 1 2 2 2 0 Necrosis inducing protein (NPP1) UPAR_LY6_2 PF16975.5 KFM80659.1 - 0.14 12.3 9.1 0.27 11.4 9.1 1.5 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 DUF3617 PF12276.8 KFM80659.1 - 0.23 11.8 5.0 0.28 11.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) Amidase_2 PF01510.25 KFM80660.1 - 8.3e-23 81.2 0.8 1.1e-22 80.8 0.8 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase GMC_oxred_N PF00732.19 KFM80661.1 - 1.2e-79 267.8 0.0 1.6e-79 267.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFM80661.1 - 2.5e-41 141.6 0.1 1.2e-40 139.3 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFM80661.1 - 0.00028 20.1 0.4 0.4 9.7 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KFM80661.1 - 0.00029 20.0 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFM80661.1 - 0.00077 19.6 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM80661.1 - 0.0021 17.7 0.0 0.0082 15.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM80661.1 - 0.017 14.4 0.0 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM80661.1 - 0.018 14.2 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KFM80661.1 - 0.041 13.1 0.0 0.09 12.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KFM80661.1 - 0.11 11.2 0.0 0.22 10.2 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein adh_short_C2 PF13561.6 KFM80662.1 - 5.2e-65 219.3 0.1 6.7e-65 218.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM80662.1 - 3.3e-52 176.8 1.3 3.9e-52 176.6 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM80662.1 - 5.4e-07 29.7 0.5 7.7e-07 29.2 0.5 1.1 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 KFM80662.1 - 0.047 14.0 0.2 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain PMT_4TMC PF16192.5 KFM80664.1 - 2.7e-48 164.2 10.0 3.1e-48 164.0 10.0 1.0 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 KFM80665.1 - 0.00097 18.8 5.2 0.0013 18.3 5.2 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 KFM80665.1 - 0.0033 17.3 0.5 0.0048 16.8 0.2 1.4 1 1 0 1 1 1 1 MIR domain Bac_export_1 PF01311.20 KFM80665.1 - 0.0038 16.8 0.4 0.0042 16.7 0.4 1.1 1 0 0 1 1 1 1 Bacterial export proteins, family 1 DUF1829 PF08862.10 KFM80666.1 - 0.056 13.9 0.5 0.11 13.1 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF1829 XK-related PF09815.9 KFM80667.1 - 2e-33 115.9 17.4 2.5e-33 115.6 17.4 1.1 1 0 0 1 1 1 1 XK-related protein DUF4064 PF13273.6 KFM80667.1 - 0.052 13.8 0.4 0.052 13.8 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Connexin PF00029.19 KFM80667.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.3 2 0 0 2 2 2 0 Connexin DUF4428 PF14471.6 KFM80669.1 - 0.049 13.6 6.8 0.12 12.3 6.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) FAD_binding_7 PF03441.14 KFM80670.1 - 2.5e-78 262.2 0.6 3.3e-78 261.8 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFM80671.1 - 7e-45 153.0 0.0 9.3e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 DNA photolyase ERCC4 PF02732.15 KFM80672.1 - 4.8e-24 85.3 0.2 3.9e-23 82.4 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain NifQ PF04891.12 KFM80672.1 - 0.11 12.9 0.4 0.22 11.9 0.4 1.5 1 0 0 1 1 1 0 NifQ YojJ PF10372.9 KFM80672.1 - 5.7 7.1 7.5 1.5 9.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus WD40 PF00400.32 KFM80673.1 - 8.3e-07 29.6 8.2 0.039 14.8 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF1899 PF08953.11 KFM80673.1 - 0.0019 18.1 0.0 0.0046 16.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 KFM80673.1 - 0.0032 17.7 0.0 0.12 12.7 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Lipase_GDSL_2 PF13472.6 KFM80674.1 - 2.2e-10 41.2 0.0 3.3e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFM80674.1 - 0.0019 18.2 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ret2_MD PF18528.1 KFM80674.1 - 0.1 13.0 0.0 0.45 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain BTB PF00651.31 KFM80675.1 - 1.2e-07 31.9 1.2 1.2e-07 31.9 1.2 2.1 3 0 0 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFM80675.1 - 0.0082 16.2 0.3 0.52 10.4 0.0 2.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch TetR_C_19 PF17924.1 KFM80675.1 - 0.017 15.7 1.3 0.033 14.8 0.4 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ABC_tran PF00005.27 KFM80679.1 - 2.3e-14 54.1 0.1 4e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KFM80679.1 - 3.4e-08 33.2 19.0 6.4e-08 32.3 19.0 1.5 1 0 0 1 1 1 1 ABC-2 type transporter zf-C3HC4_3 PF13920.6 KFM80680.1 - 7.5e-11 41.7 5.6 1.1e-10 41.2 5.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM80680.1 - 2.7e-10 39.9 6.4 3.7e-10 39.5 6.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM80680.1 - 3.6e-10 40.0 9.5 5e-10 39.5 9.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM80680.1 - 4.4e-10 39.2 6.9 7.1e-10 38.6 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM80680.1 - 7e-08 32.4 5.4 1.5e-07 31.3 2.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM80680.1 - 5.1e-07 29.4 6.9 7.3e-07 29.0 6.9 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFM80680.1 - 5.8e-07 29.4 5.8 8.4e-07 28.9 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFM80680.1 - 7.3e-06 26.2 6.6 1.2e-05 25.4 6.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFM80680.1 - 9e-06 25.7 2.3 1.3e-05 25.1 2.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFM80680.1 - 0.00014 21.9 6.9 0.00021 21.4 6.9 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KFM80680.1 - 0.00089 19.2 2.1 0.0013 18.7 2.1 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 KFM80680.1 - 0.0039 17.3 1.8 0.0089 16.1 1.8 1.6 1 1 0 1 1 1 1 Zinc-binding RING-finger Rtf2 PF04641.12 KFM80680.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_4 PF14570.6 KFM80680.1 - 0.012 15.4 5.2 0.027 14.3 5.2 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KFM80680.1 - 0.14 12.4 6.8 0.35 11.1 2.6 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 KFM80680.1 - 0.8 9.5 8.6 0.11 12.3 3.5 2.2 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KFM80680.1 - 1.1 8.9 7.0 2 8.1 7.0 1.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type BTB PF00651.31 KFM80681.1 - 2.9e-07 30.7 0.0 2.1e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 KFM80681.1 - 0.00013 22.1 0.1 0.00019 21.6 0.1 1.2 1 0 0 1 1 1 1 MATH domain CHGN PF05679.16 KFM80682.1 - 7.9e-82 275.7 0.0 9.9e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFM80682.1 - 6.4e-10 38.6 1.1 1.4e-09 37.5 1.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFM80682.1 - 0.1 12.1 0.2 0.74 9.2 0.2 2.0 1 1 0 1 1 1 0 Glycosyltransferase like family 2 NUDE_C PF04880.13 KFM80682.1 - 0.1 13.1 1.2 0.25 11.8 1.2 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Astacin PF01400.24 KFM80683.1 - 1.4e-59 201.0 0.8 1.5e-59 200.8 0.8 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM80683.1 - 0.0011 18.8 2.5 0.0092 15.8 0.5 2.4 2 1 1 3 3 3 1 Matrixin Peptidase_M66 PF10462.9 KFM80683.1 - 0.0037 16.3 0.3 0.0043 16.0 0.3 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 KFM80683.1 - 0.0084 15.8 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KFM80683.1 - 0.044 14.3 0.4 0.083 13.4 0.4 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFM80683.1 - 0.12 12.5 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 KFM80683.1 - 0.15 10.6 0.5 0.3 9.6 0.3 1.5 2 0 0 2 2 2 0 Putative peptidase family Peptidase_M57 PF12388.8 KFM80683.1 - 0.17 11.5 1.2 0.39 10.3 1.2 1.7 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Astacin PF01400.24 KFM80684.1 - 9.3e-52 175.4 0.0 1.1e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFM80684.1 - 0.00024 20.2 0.3 0.00031 19.8 0.3 1.1 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 KFM80684.1 - 0.014 15.3 0.3 0.017 15.0 0.3 1.3 1 1 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 KFM80684.1 - 0.017 15.6 0.1 0.027 15.0 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M8 PF01457.16 KFM80684.1 - 0.096 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin Reprolysin_4 PF13583.6 KFM80684.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 KFM80684.1 - 0.13 10.9 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase family CTF_NFI PF00859.18 KFM80684.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region RRM_1 PF00076.22 KFM80685.1 - 5.2e-11 42.2 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KFM80686.1 - 2.2e-19 68.8 12.2 4.3e-19 67.8 12.2 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 KFM80686.1 - 8.9e-19 67.7 3.8 8.9e-19 67.7 3.8 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KFM80687.1 - 9.3e-22 76.6 0.0 1.3e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KFM80687.1 - 0.00064 19.6 0.0 0.0038 17.1 0.0 1.9 1 1 1 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KFM80687.1 - 0.0061 16.7 0.0 0.0092 16.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif Aa_trans PF01490.18 KFM80688.1 - 9.6e-42 143.1 32.7 1.1e-41 142.9 32.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM80688.1 - 3.6e-06 26.3 24.9 2e-05 23.8 24.9 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family HRG PF16954.5 KFM80688.1 - 0.26 11.7 0.2 0.26 11.7 0.2 4.2 6 0 0 6 6 6 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Lig_chan PF00060.26 KFM80690.1 - 4e-06 26.7 0.2 4.8e-06 26.5 0.2 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFM80690.1 - 0.06 13.5 0.0 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Solute_trans_a PF03619.16 KFM80691.1 - 3.5e-22 79.2 13.6 4.2e-22 78.9 13.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF5391 PF17369.2 KFM80691.1 - 0.54 10.3 8.0 0.08 13.0 2.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5391) BAG PF02179.16 KFM80692.1 - 2.9e-19 69.3 3.3 4.4e-19 68.7 1.3 2.4 2 0 0 2 2 2 1 BAG domain XhlA PF10779.9 KFM80692.1 - 7.6 6.8 12.2 3.4 8.0 8.6 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Kelch_3 PF13415.6 KFM80693.1 - 9.4e-22 76.8 9.2 8.9e-09 35.4 0.5 4.6 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFM80693.1 - 9.7e-20 70.3 3.4 5e-05 23.2 0.9 4.6 3 2 1 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM80693.1 - 1.4e-18 66.4 3.4 0.0018 18.5 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 KFM80693.1 - 6.8e-16 57.6 9.7 3.1e-05 23.5 0.4 5.2 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KFM80693.1 - 5.5e-11 42.2 8.7 0.027 14.5 0.2 5.3 4 1 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 KFM80693.1 - 1.1e-08 34.7 3.9 0.1 12.6 0.1 4.8 4 1 0 4 4 4 3 Kelch motif ATP-synt_ab_C PF00306.27 KFM80694.1 - 0.0039 17.5 1.0 0.0049 17.2 1.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Prefoldin PF02996.17 KFM80695.1 - 1.3e-15 57.3 1.7 1.7e-15 57.0 0.1 1.9 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 KFM80695.1 - 2.4e-05 24.3 0.2 2.4e-05 24.3 0.2 2.7 3 0 0 3 3 3 1 Prefoldin subunit DUF5514 PF17633.2 KFM80695.1 - 1.1 9.5 6.6 3.4 7.9 3.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5514) TRAF_BIRC3_bd PF16673.5 KFM80695.1 - 1.7 8.5 5.5 1.6 8.6 0.1 3.1 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Ribosomal_L1 PF00687.21 KFM80696.1 - 5.6e-46 156.8 4.7 6.4e-46 156.7 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 KFM80696.1 - 0.05 13.7 2.3 0.094 12.8 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function TetR PF13972.6 KFM80696.1 - 0.052 13.2 0.4 0.13 12.0 0.1 1.7 2 0 0 2 2 2 0 Bacterial transcriptional repressor GHL13 PF14883.6 KFM80696.1 - 0.067 12.2 0.1 0.092 11.8 0.1 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 ATAD4 PF15321.6 KFM80698.1 - 0.13 13.7 9.0 0.2 13.0 9.0 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 RNase_H PF00075.24 KFM80700.1 - 0.0014 18.9 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 RNase H Med26 PF08711.11 KFM80701.1 - 1.7e-07 31.2 3.5 2.4e-07 30.7 0.4 2.5 2 1 0 2 2 2 1 TFIIS helical bundle-like domain TFIIS_M PF07500.14 KFM80701.1 - 0.0023 18.4 2.2 0.0037 17.7 2.2 1.6 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain DUF4838 PF16126.5 KFM80701.1 - 0.034 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Forkhead PF00250.18 KFM80704.1 - 1.3e-39 134.3 0.1 2.1e-39 133.6 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain AP3D1 PF06375.11 KFM80705.1 - 7.7e-38 130.2 6.9 7.7e-38 130.2 6.9 2.9 3 0 0 3 3 3 2 AP-3 complex subunit delta-1 Adaptin_N PF01602.20 KFM80705.1 - 8.2e-27 94.0 4.7 1.1e-26 93.5 4.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Adaptin_N PF01602.20 KFM80706.1 - 0.00017 20.3 0.2 0.00018 20.2 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region RRM_7 PF16367.5 KFM80707.1 - 6.9e-39 131.9 0.0 2e-36 124.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif CEBP_ZZ PF16366.5 KFM80707.1 - 7.2e-21 74.2 6.0 1.9e-20 72.9 6.0 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFM80707.1 - 3.1e-13 49.3 0.0 1.1e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.24 KFM80707.1 - 1 9.6 7.2 2.6 8.3 7.2 1.6 1 0 0 1 1 1 0 B-box zinc finger Defensin_beta PF00711.19 KFM80708.1 - 0.023 14.7 2.3 2.4 8.2 0.4 2.1 2 0 0 2 2 2 0 Beta defensin PID PF00640.23 KFM80710.1 - 1.8e-27 96.1 0.5 4.1e-27 94.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFM80710.1 - 5.2e-13 49.3 0.3 1.8e-12 47.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFM80710.1 - 6.7e-08 32.6 0.0 1.7e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) HAP1_N PF04849.13 KFM80710.1 - 0.0041 16.4 0.4 0.0062 15.8 0.4 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region KIAA1430 PF13879.6 KFM80710.1 - 0.012 16.4 2.4 0.035 14.9 2.4 1.9 1 0 0 1 1 1 0 KIAA1430 homologue CSTF1_dimer PF16699.5 KFM80710.1 - 0.027 14.2 0.1 0.055 13.2 0.1 1.5 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain Herpes_BLRF2 PF05812.12 KFM80710.1 - 0.03 14.4 0.8 0.06 13.5 0.8 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein ZapB PF06005.12 KFM80710.1 - 0.037 14.5 2.8 0.09 13.2 2.8 1.7 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 KFM80710.1 - 0.039 14.0 2.5 0.09 12.9 2.5 1.6 1 0 0 1 1 1 0 Basic region leucine zipper GIT_CC PF16559.5 KFM80710.1 - 0.043 13.7 2.5 0.12 12.2 2.5 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 KFM80710.1 - 0.043 13.9 2.5 0.11 12.6 2.5 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 KFM80710.1 - 0.14 12.0 1.8 0.32 10.8 1.8 1.5 1 0 0 1 1 1 0 Septum formation initiator V-set PF07686.17 KFM80711.1 - 1.2e-07 31.9 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM80711.1 - 5.1e-07 30.2 0.0 9.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM80711.1 - 5.2e-06 26.7 0.0 1.9e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM80711.1 - 0.00033 20.8 0.0 0.0016 18.6 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM80711.1 - 0.00077 19.5 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Big_3_2 PF12245.8 KFM80711.1 - 0.01 16.1 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain ribosomal_L24 PF17136.4 KFM80714.1 - 2.6e-12 46.9 0.0 8.4e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 KFM80714.1 - 0.0018 18.2 3.6 0.0018 18.2 3.6 1.9 2 0 0 2 2 2 1 KOW motif PWWP PF00855.17 KFM80717.1 - 0.045 14.2 0.5 0.2 12.1 0.0 2.5 2 0 0 2 2 2 0 PWWP domain AT_hook PF02178.19 KFM80717.1 - 1.4 9.1 6.9 6.2 7.0 6.9 2.2 1 0 0 1 1 1 0 AT hook motif Laminin_G_2 PF02210.24 KFM80718.1 - 1.1e-24 87.4 0.0 7.4e-24 84.7 0.0 2.2 3 0 0 3 3 3 1 Laminin G domain Laminin_G_1 PF00054.23 KFM80718.1 - 4.4e-24 85.2 0.0 2.1e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 Laminin G domain EGF PF00008.27 KFM80718.1 - 0.042 14.2 5.8 0.12 12.8 5.8 1.7 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 KFM80718.1 - 0.064 13.9 1.8 0.15 12.8 1.8 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 KFM80718.1 - 0.48 10.8 4.8 0.96 9.9 4.8 1.5 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 KFM80719.1 - 1e-12 48.1 21.8 2.5e-07 30.9 6.9 2.5 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFM80719.1 - 3.4e-06 27.5 20.1 6.6e-05 23.4 4.7 3.0 3 1 0 3 3 3 2 Human growth factor-like EGF EGF_3 PF12947.7 KFM80719.1 - 0.0031 17.7 17.3 0.0064 16.7 4.3 2.5 2 0 0 2 2 2 2 EGF domain FXa_inhibition PF14670.6 KFM80719.1 - 0.052 13.8 19.9 0.19 12.1 6.5 2.5 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 KFM80719.1 - 0.1 12.7 21.7 2.8 8.1 14.3 2.3 1 1 1 2 2 2 0 Laminin EGF domain cEGF PF12662.7 KFM80719.1 - 0.18 11.8 14.8 0.19 11.7 9.3 2.9 2 1 0 2 2 2 0 Complement Clr-like EGF-like EGF_2 PF07974.13 KFM80719.1 - 0.21 12.0 24.8 2 8.8 6.5 2.8 2 1 0 2 2 2 0 EGF-like domain Kazal_2 PF07648.15 KFM80724.1 - 1.5e-17 63.4 13.9 3.7e-11 43.0 3.9 3.7 3 1 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM80724.1 - 1.5e-10 40.9 26.5 1.8e-06 27.9 12.3 3.3 2 2 0 2 2 2 2 Kazal-type serine protease inhibitor domain DUF4732 PF15876.5 KFM80724.1 - 4.7 7.3 6.9 0.32 11.1 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4732) RAP-1 PF03085.15 KFM80724.1 - 8.4 6.0 6.9 13 5.4 6.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) 7tm_3 PF00003.22 KFM80725.1 - 0.00011 22.0 4.0 0.00015 21.6 4.0 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR EamA PF00892.20 KFM80725.1 - 0.014 15.6 0.1 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 EamA-like transporter family DUF5367 PF17329.2 KFM80725.1 - 0.081 13.1 0.4 0.13 12.4 0.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5367) DUF3290 PF11694.8 KFM80725.1 - 0.11 12.4 2.8 0.19 11.7 2.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3290) 7tm_3 PF00003.22 KFM80726.1 - 1.9e-17 63.8 5.1 2.1e-17 63.6 5.1 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 KFM80727.1 - 8.2e-06 25.2 0.0 1.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region P53_TAD PF08563.11 KFM80727.1 - 0.0057 16.1 0.4 0.013 14.9 0.4 1.6 1 0 0 1 1 1 1 P53 transactivation motif ANF_receptor PF01094.28 KFM80728.1 - 9e-14 51.3 0.0 1.9e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region ANF_receptor PF01094.28 KFM80729.1 - 9.8e-09 34.8 0.0 1.1e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 KFM80730.1 - 5.7e-23 81.6 0.0 5.9e-12 45.3 0.0 2.3 2 1 0 2 2 2 2 Receptor family ligand binding region ANF_receptor PF01094.28 KFM80731.1 - 0.0013 17.9 0.1 0.0013 17.9 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Phospholip_A2_2 PF05826.12 KFM80733.1 - 2.8e-20 72.3 0.0 8.4e-20 70.8 0.0 1.8 2 0 0 2 2 2 1 Phospholipase A2 Peptidase_M3_N PF08439.10 KFM80733.1 - 0.0074 16.5 0.6 0.026 14.8 0.1 2.1 2 0 0 2 2 2 1 Oligopeptidase F HSA PF07529.13 KFM80733.1 - 0.097 13.0 1.4 0.16 12.3 1.4 1.4 1 0 0 1 1 1 0 HSA TSP_1 PF00090.19 KFM80734.1 - 3.8e-08 33.4 5.7 2.1e-07 31.0 5.7 2.4 1 0 0 1 1 1 1 Thrombospondin type 1 domain Somatomedin_B PF01033.17 KFM80734.1 - 5.8e-07 29.8 8.2 5.8e-07 29.8 8.2 3.9 4 0 0 4 4 4 2 Somatomedin B domain Band_7 PF01145.25 KFM80735.1 - 9.3e-19 68.1 0.0 9.3e-19 68.1 0.0 2.3 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 KFM80735.1 - 1.3e-07 31.8 8.9 1.3e-07 31.8 8.9 3.7 2 2 2 4 4 4 1 Flotillin YjbH PF06082.11 KFM80735.1 - 0.7 8.6 6.7 0.92 8.2 6.7 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Astacin PF01400.24 KFM80736.1 - 3.8e-18 65.8 0.0 4.7e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 KFM80737.1 - 1.1e-25 90.3 0.1 2.2e-25 89.4 0.0 1.5 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) CUB PF00431.20 KFM80737.1 - 9.8e-10 38.8 0.0 2.1e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 CUB domain Astacin PF01400.24 KFM80738.1 - 3.8e-55 186.5 0.0 4.8e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM80738.1 - 2.3e-05 24.3 0.1 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 2 Matrixin Reprolysin_4 PF13583.6 KFM80738.1 - 0.058 13.0 0.1 0.086 12.5 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KFM80738.1 - 0.13 12.8 0.7 0.21 12.1 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFM80738.1 - 0.7 9.0 2.5 0.8 8.9 0.9 1.8 2 0 0 2 2 2 0 Met-zincin Astacin PF01400.24 KFM80740.1 - 0.06 13.0 0.0 0.076 12.6 0.0 1.1 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) RCC1 PF00415.18 KFM80742.1 - 1.8e-26 92.5 6.4 2.7e-14 53.5 1.2 3.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFM80742.1 - 2e-21 76.3 0.6 1.6e-20 73.3 0.1 2.1 1 1 1 2 2 2 1 BTB/POZ domain RCC1_2 PF13540.6 KFM80742.1 - 7.4e-16 57.5 8.0 3.1e-08 33.2 0.3 3.5 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat BACK PF07707.15 KFM80742.1 - 0.00013 22.0 1.0 0.00081 19.5 0.2 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch RCC1 PF00415.18 KFM80743.1 - 0.00047 20.7 0.5 0.00071 20.1 0.1 1.5 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat zf-C2HE PF16278.5 KFM80745.1 - 1.2e-15 57.6 0.1 2.3e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KFM80745.1 - 5.1e-13 49.5 0.9 5.1e-13 49.5 0.9 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KFM80745.1 - 0.00023 21.8 2.1 0.0004 21.1 0.3 2.2 2 1 1 3 3 3 1 HIT domain Ribosomal_L34e PF01199.18 KFM80745.1 - 0.077 13.3 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L34e zf-C2H2_4 PF13894.6 KFM80745.1 - 0.11 13.4 0.4 0.11 13.4 0.4 2.4 2 1 1 3 3 3 0 C2H2-type zinc finger IF2_N PF04760.15 KFM80745.1 - 0.15 11.9 0.4 0.39 10.6 0.4 1.6 1 1 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zf-H2C2_2 PF13465.6 KFM80747.1 - 8.8e-57 187.2 88.9 1.6e-08 34.6 0.2 14.2 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80747.1 - 4.3e-47 156.0 106.5 7.9e-07 29.2 1.3 13.3 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80747.1 - 2.4e-41 136.8 100.6 3.3e-05 24.4 1.1 13.2 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 KFM80747.1 - 1.4e-29 101.5 82.7 0.0015 18.9 1.1 12.9 13 0 0 13 13 13 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM80747.1 - 8.3e-25 86.5 77.9 0.0035 17.6 0.6 13.2 12 1 1 13 13 13 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM80747.1 - 3.3e-11 42.9 88.7 0.00014 21.7 0.6 12.6 13 0 0 13 13 13 7 C2H2-type zinc finger BolA PF01722.18 KFM80747.1 - 4.9e-06 26.7 18.6 0.54 10.6 0.2 7.8 2 2 4 6 6 6 4 BolA-like protein C1_4 PF07975.12 KFM80747.1 - 0.21 11.9 0.0 0.21 11.9 0.0 8.1 2 1 8 11 11 11 0 TFIIH C1-like domain zf-CHCC PF10276.9 KFM80747.1 - 0.75 9.9 12.3 11 6.2 0.0 6.3 7 0 0 7 7 7 0 Zinc-finger domain ADK_lid PF05191.14 KFM80747.1 - 3 7.9 0.0 0.64 10.1 0.6 7.0 5 3 1 6 6 6 0 Adenylate kinase, active site lid GAGA PF09237.11 KFM80747.1 - 4.6 7.1 34.0 0.46 10.3 0.1 7.4 4 2 5 9 9 9 0 GAGA factor zf_UBZ PF18439.1 KFM80747.1 - 5.4 6.7 49.7 1.3 8.7 0.2 10.5 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KFM80748.1 - 5.4e-17 61.4 22.7 2.6e-06 27.6 0.0 4.7 4 2 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM80748.1 - 6e-15 54.7 18.9 0.00029 21.4 0.3 4.7 4 1 1 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM80748.1 - 1.2e-14 53.8 21.4 0.00011 22.5 3.0 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-met PF12874.7 KFM80748.1 - 9.2e-08 32.2 17.5 0.34 11.4 1.9 4.7 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM80748.1 - 4.1e-07 30.1 13.7 0.055 13.8 0.4 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM80748.1 - 4.2e-07 29.8 28.7 0.042 13.8 0.3 5.2 6 0 0 6 6 6 4 C2H2-type zinc finger BolA PF01722.18 KFM80748.1 - 2.8e-05 24.3 1.6 0.00048 20.3 0.5 2.7 1 1 1 2 2 2 2 BolA-like protein zf-Di19 PF05605.12 KFM80748.1 - 0.00022 21.5 17.1 0.082 13.2 0.3 3.4 2 2 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFM80748.1 - 0.00054 20.2 11.2 0.0055 17.0 3.0 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KFM80748.1 - 0.0013 18.4 9.3 0.0049 16.6 1.7 3.0 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-MYST PF17772.1 KFM80748.1 - 0.0019 17.7 9.5 0.16 11.6 0.1 4.1 1 1 3 4 4 4 1 MYST family zinc finger domain Ta0938 PF11494.8 KFM80748.1 - 0.015 15.5 8.7 0.15 12.4 1.7 3.4 1 1 3 4 4 4 0 Ta0938 zf-C2HC_2 PF13913.6 KFM80748.1 - 0.028 14.3 10.0 5.5 7.0 0.2 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-met2 PF12907.7 KFM80748.1 - 0.037 14.2 13.4 2.6 8.3 0.4 4.5 4 0 0 4 4 4 0 Zinc-binding Baculo_IE-1 PF05290.11 KFM80748.1 - 0.048 13.6 15.0 33 4.4 15.0 3.7 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) MafB19-deam PF14437.6 KFM80748.1 - 0.15 11.8 0.3 0.15 11.8 0.3 2.7 1 1 0 2 2 2 0 MafB19-like deaminase Vps39_2 PF10367.9 KFM80748.1 - 0.41 11.1 20.5 0.2 12.1 2.8 3.5 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 FYVE PF01363.21 KFM80748.1 - 0.89 9.7 23.2 1.4e+03 -0.5 22.5 3.5 1 1 0 1 1 1 0 FYVE zinc finger zf-TFIIIC PF12660.7 KFM80748.1 - 2.1 8.3 16.4 0.99 9.4 2.0 2.4 2 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex XPA_N PF01286.18 KFM80748.1 - 2.2 8.4 13.4 4.9 7.3 0.1 4.1 4 0 0 4 4 4 0 XPA protein N-terminal Ribosomal_L37ae PF01780.19 KFM80748.1 - 4.1 7.5 17.4 2.6 8.2 0.9 3.3 1 1 2 3 3 3 0 Ribosomal L37ae protein family zf-HIT PF04438.16 KFM80748.1 - 7.2 6.6 18.6 2.3 8.2 0.2 4.6 5 0 0 5 5 5 0 HIT zinc finger DPPIV_N PF00930.21 KFM80749.1 - 0.0036 16.1 0.0 0.0091 14.8 0.0 1.6 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFM80750.1 - 9e-57 192.0 0.1 1.4e-56 191.3 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 KFM80750.1 - 9.9e-49 166.0 0.3 1.4e-48 165.5 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.18 KFM80750.1 - 4.9e-13 49.3 0.2 3.6e-11 43.2 0.1 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KFM80750.1 - 4.5e-06 26.4 0.2 4.2e-05 23.2 0.2 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KFM80750.1 - 6e-06 27.0 0.1 1.1e-05 26.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KFM80750.1 - 0.00066 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KFM80750.1 - 0.00067 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFM80750.1 - 0.02 14.7 0.3 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KFM80750.1 - 0.028 13.7 1.0 6.1 6.0 0.1 2.4 1 1 0 2 2 2 0 Serine aminopeptidase, S33 AXE1 PF05448.12 KFM80750.1 - 0.038 12.7 0.2 0.79 8.3 0.1 2.6 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KFM80750.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Deltameth_res PF16020.5 KFM80751.1 - 1.1e-11 44.4 0.0 2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Deltamethrin resistance Frag1 PF10277.9 KFM80752.1 - 4.7e-22 78.6 10.3 5.2e-22 78.5 10.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DAGK_prokar PF01219.19 KFM80752.1 - 0.25 11.2 2.9 0.23 11.3 0.5 2.0 2 1 0 2 2 2 0 Prokaryotic diacylglycerol kinase FimA PF16970.5 KFM80754.1 - 0.087 13.0 0.0 0.089 13.0 0.0 1.1 1 0 0 1 1 1 0 Type-1 fimbrial protein, A Erv26 PF04148.13 KFM80755.1 - 7.7e-24 84.7 2.7 4.5e-23 82.2 2.7 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Gate PF07670.14 KFM80755.1 - 0.013 15.8 0.1 0.015 15.5 0.1 1.1 1 0 0 1 1 1 0 Nucleoside recognition Guanylate_kin PF00625.21 KFM80756.1 - 8.9e-54 181.9 0.4 9.4e-46 155.8 0.0 2.6 2 0 0 2 2 2 2 Guanylate kinase L27 PF02828.16 KFM80756.1 - 3.8e-15 55.4 0.1 8.3e-09 35.1 0.0 2.9 2 0 0 2 2 2 2 L27 domain PDZ PF00595.24 KFM80756.1 - 4.7e-11 42.9 0.5 1e-10 41.8 0.5 1.6 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 KFM80756.1 - 1.1e-09 37.8 0.3 5.6e-09 35.5 0.3 2.1 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM80756.1 - 4.9e-09 35.7 0.0 1.2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 KFM80756.1 - 3.1e-07 30.1 0.2 1.1e-06 28.3 0.2 2.1 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM80756.1 - 1.7e-06 28.3 0.1 4.9e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KFM80756.1 - 0.00037 20.3 0.1 0.0011 18.8 0.1 1.9 1 1 0 1 1 1 1 Variant SH3 domain Tricorn_PDZ PF14685.6 KFM80756.1 - 0.063 13.3 0.0 0.41 10.7 0.1 2.3 2 1 0 2 2 2 0 Tricorn protease PDZ domain Phage_holin_3_6 PF07332.11 KFM80757.1 - 0.022 14.8 0.1 0.029 14.4 0.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM171 PF15471.6 KFM80757.1 - 0.034 13.1 0.2 0.045 12.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Tetraspanin PF00335.20 KFM80757.1 - 0.15 11.8 5.8 0.029 14.1 2.7 1.4 2 0 0 2 2 2 0 Tetraspanin family DUF2371 PF10177.9 KFM80757.1 - 0.51 10.5 2.8 1.2 9.4 2.7 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Neurensin PF14927.6 KFM80757.1 - 1 9.1 5.3 0.25 11.1 0.4 2.0 1 1 1 2 2 2 0 Neurensin TMEM174 PF15029.6 KFM80757.1 - 6 6.5 5.3 8.9 6.0 4.5 1.5 1 1 0 1 1 1 0 Transmembrane protein 174 DUF4769 PF15992.5 KFM80758.1 - 0.2 11.4 0.5 0.26 11.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) PIRT PF15099.6 KFM80759.1 - 0.0028 17.2 0.0 0.0028 17.2 0.0 2.5 3 0 0 3 3 3 1 Phosphoinositide-interacting protein family Shisa PF13908.6 KFM80759.1 - 0.0086 16.3 1.3 0.0086 16.3 1.3 2.6 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator DUF4418 PF14387.6 KFM80759.1 - 0.18 12.0 4.0 1.7 8.9 0.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4418) DUF3098 PF11297.8 KFM80759.1 - 9.7 5.9 6.6 33 4.2 6.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3098) DNA_primase_lrg PF04104.14 KFM80760.1 - 8.3e-14 51.6 4.1 1.1e-13 51.2 4.1 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit AFP_2 PF18815.1 KFM80760.1 - 0.36 11.1 1.9 0.56 10.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat tRNA-synt_2e PF02091.15 KFM80761.1 - 0.031 13.5 0.3 0.035 13.4 0.3 1.0 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit Ank_5 PF13857.6 KFM80762.1 - 1e-32 111.8 1.2 3.9e-08 33.4 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM80762.1 - 1.7e-28 99.1 2.0 3.6e-11 43.5 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM80762.1 - 1.2e-24 83.6 0.3 0.0003 21.0 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KFM80762.1 - 4.4e-24 83.8 5.4 3.7e-05 24.0 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KFM80762.1 - 3.3e-23 81.8 5.0 1.8e-05 25.2 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SAM_1 PF00536.30 KFM80762.1 - 3.1e-15 56.4 0.1 7e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM80762.1 - 6.5e-11 42.2 0.3 2.2e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) LRRFIP PF09738.9 KFM80762.1 - 0.018 14.5 0.5 0.029 13.8 0.5 1.2 1 0 0 1 1 1 0 LRRFIP family CFTR_R PF14396.6 KFM80762.1 - 0.028 14.0 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Lzipper-MIP1 PF14389.6 KFM80762.1 - 0.049 13.9 1.9 0.11 12.9 1.9 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Dynamin_N PF00350.23 KFM80763.1 - 0.011 15.8 1.7 0.017 15.1 1.2 1.6 2 0 0 2 2 2 0 Dynamin family Glyco_transf_7N PF13733.6 KFM80764.1 - 7.8e-53 177.7 0.0 1.1e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFM80764.1 - 9.5e-29 98.9 0.1 1.8e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase ASC PF00858.24 KFM80766.1 - 0.0024 16.9 4.0 0.0024 16.9 4.0 1.3 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Suppressor_P21 PF11479.8 KFM80768.1 - 0.04 14.1 0.1 0.047 13.9 0.1 1.1 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain MMADHC PF10229.9 KFM80771.1 - 4.4e-65 220.1 0.0 5e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein zf-C2H2 PF00096.26 KFM80773.1 - 7.8e-24 82.8 130.4 1.4e-06 28.4 1.1 14.3 14 0 0 14 14 14 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80773.1 - 3.5e-23 80.3 128.2 5.7e-05 23.6 1.2 14.1 15 0 0 15 15 13 12 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM80773.1 - 1.8e-20 72.4 111.3 5.1e-05 23.5 1.2 13.6 13 1 0 13 13 13 10 Zinc-finger double domain zf-met PF12874.7 KFM80773.1 - 8.7e-14 51.4 91.0 0.00014 22.1 0.9 13.4 13 0 0 13 13 13 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM80773.1 - 1.5e-08 34.7 96.0 0.00088 19.5 0.3 13.0 13 0 0 13 13 13 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM80773.1 - 9.2e-07 28.7 79.2 0.0065 16.4 1.5 10.8 10 0 0 10 10 10 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM80773.1 - 1.5e-06 27.9 11.5 1.7e-06 27.6 6.2 10.3 10 2 0 10 10 8 2 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 KFM80773.1 - 2.6e-05 24.9 54.6 0.0017 19.0 11.6 5.5 1 1 4 5 5 5 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KFM80773.1 - 8.7e-05 22.8 86.8 0.046 14.1 16.8 8.5 1 1 5 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KFM80773.1 - 0.015 15.5 2.3 0.015 15.5 2.3 8.8 3 2 6 10 10 10 0 Drought induced 19 protein (Di19), zinc-binding zf-Paramyx-P PF13008.7 KFM80773.1 - 0.52 9.8 6.9 0.61 9.6 2.2 3.4 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein RseC_MucC PF04246.12 KFM80773.1 - 5 7.1 11.9 0.53 10.2 0.4 3.2 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC ROS_MUCR PF05443.11 KFM80773.1 - 6.3 6.9 10.6 9.2 6.3 4.6 4.3 3 1 0 3 3 3 0 ROS/MUCR transcriptional regulator protein EGF_CA PF07645.15 KFM80774.1 - 0.00013 22.1 2.9 0.00013 22.1 2.9 14.4 4 2 9 13 13 13 1 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 KFM80774.1 - 0.0054 16.7 3.6 0.0054 16.7 3.6 13.3 9 3 6 15 15 15 2 MSP1 EGF domain 1 Ank_4 PF13637.6 KFM80774.1 - 0.025 15.2 0.1 0.071 13.7 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) EGF PF00008.27 KFM80774.1 - 0.03 14.6 3.8 0.03 14.6 3.8 14.9 13 2 0 13 13 13 0 EGF-like domain hEGF PF12661.7 KFM80774.1 - 0.1 13.3 0.5 0.1 13.3 0.5 17.6 15 6 3 18 18 18 0 Human growth factor-like EGF Tnp_P_element PF12017.8 KFM80775.1 - 2.8e-49 167.5 0.1 3.2e-49 167.3 0.1 1.0 1 0 0 1 1 1 1 Transposase protein ArgoMid PF16487.5 KFM80776.1 - 0.096 13.0 0.0 0.13 12.6 0.0 1.3 1 1 0 1 1 1 0 Mid domain of argonaute EB PF01683.18 KFM80776.1 - 0.37 11.1 6.6 1.7 9.0 2.8 2.2 1 1 1 2 2 2 0 EB module Hirudin PF00713.17 KFM80776.1 - 3.5 8.0 8.6 4.1 7.8 1.2 2.9 1 1 1 3 3 3 0 Hirudin DUF5330 PF17264.2 KFM80776.1 - 6.1 6.9 5.7 5.4 7.1 0.3 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5330) Cir_N PF10197.9 KFM80778.1 - 3.3e-08 33.6 11.5 3.3e-08 33.6 11.5 4.9 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF2856 PF11043.8 KFM80778.1 - 0.84 9.8 8.8 3.6 7.8 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2856) bZIP_1 PF00170.21 KFM80779.1 - 4.6e-18 65.1 15.9 8.1e-18 64.3 15.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.17 KFM80779.1 - 4.2e-16 58.1 0.2 1.1e-15 56.7 0.2 1.7 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.15 KFM80779.1 - 7.6e-07 29.1 14.6 1.7e-06 28.0 14.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFM80779.1 - 0.01 16.3 8.1 0.022 15.3 8.1 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4988 PF16378.5 KFM80779.1 - 0.019 14.6 1.8 0.53 9.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function Herpes_UL52 PF03121.15 KFM80780.1 - 2.7e-12 46.4 0.5 5.3e-12 45.5 0.5 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase SANT_DAMP1_like PF16282.5 KFM80783.1 - 1.7e-34 117.8 0.4 3.6e-34 116.8 0.4 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 KFM80783.1 - 1.6e-15 57.4 11.3 3.3e-15 56.4 11.3 1.5 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 KFM80783.1 - 0.087 13.1 1.8 4.5 7.6 1.1 3.4 2 1 0 2 2 2 0 Myb-like DNA-binding domain Cir_N PF10197.9 KFM80783.1 - 7.1 6.9 14.0 3.7 7.8 6.4 2.9 2 1 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR DMAP1 PF05499.12 KFM80784.1 - 9.5e-37 126.4 0.6 1.2e-36 126.1 0.6 1.0 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Pkinase_Tyr PF07714.17 KFM80785.1 - 2.1e-71 240.2 0.0 2.9e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WIF PF02019.18 KFM80785.1 - 5.9e-41 139.2 0.0 1.1e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 WIF domain Pkinase PF00069.25 KFM80785.1 - 3.3e-27 95.5 0.0 5.7e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFM80785.1 - 0.029 13.7 2.0 0.1 11.9 2.0 1.8 1 1 0 1 1 1 0 Kinase-like CRAL_TRIO PF00650.20 KFM80786.1 - 2.7e-21 75.9 0.4 4e-21 75.4 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM80787.1 - 2.5e-27 95.6 0.0 3.8e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM80787.1 - 3.3e-05 24.0 0.0 5.5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain ABC_membrane PF00664.23 KFM80791.1 - 2.6e-17 63.4 1.0 2.8e-17 63.3 1.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_lid_8 PF17868.1 KFM80791.1 - 0.072 13.0 0.1 0.65 9.9 0.1 2.3 2 0 0 2 2 2 0 AAA lid domain ABC_tran PF00005.27 KFM80792.1 - 9.4e-19 68.3 0.0 2.2e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM80792.1 - 2.9e-05 23.6 0.1 0.031 13.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 KFM80792.1 - 0.00032 20.8 0.1 0.00057 20.0 0.1 1.4 1 0 0 1 1 1 1 Dynamin family AAA_13 PF13166.6 KFM80792.1 - 0.0014 17.4 0.0 0.0019 16.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFM80792.1 - 0.023 14.4 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KFM80792.1 - 0.12 12.2 2.8 3.3 7.4 0.4 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFM80792.1 - 0.19 11.4 0.4 0.35 10.5 0.1 1.5 2 0 0 2 2 2 0 AAA ATPase domain 7tm_6 PF02949.20 KFM80793.1 - 0.0057 15.8 0.2 0.0065 15.6 0.2 1.0 1 0 0 1 1 1 1 7tm Odorant receptor Glyco_hydro_38 PF18438.1 KFM80793.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 ABC_membrane PF00664.23 KFM80794.1 - 1.2e-09 38.2 0.4 1.2e-09 38.2 0.4 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFM80795.1 - 4.2e-33 114.8 0.1 6.6e-33 114.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM80795.1 - 2e-06 27.4 0.8 0.004 16.6 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM80795.1 - 0.00063 19.6 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 KFM80795.1 - 0.003 16.7 0.0 0.0046 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DEAD PF00270.29 KFM80795.1 - 0.0036 17.1 0.1 0.012 15.4 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 KFM80795.1 - 0.0043 17.1 0.1 0.013 15.6 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KFM80795.1 - 0.012 15.4 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 KFM80795.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KFM80795.1 - 0.034 14.6 0.1 0.058 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFM80795.1 - 0.054 13.2 0.2 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KFM80795.1 - 0.06 13.6 0.2 0.78 10.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFM80795.1 - 0.073 12.8 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KFM80795.1 - 0.08 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KFM80795.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 KFM80795.1 - 0.14 12.2 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain NB-ARC PF00931.22 KFM80795.1 - 0.14 11.3 0.0 0.36 10.0 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain Acyltransf_C PF16076.5 KFM80796.1 - 1.1e-23 83.1 0.1 2.4e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KFM80796.1 - 1.5e-14 53.8 0.1 4.7e-14 52.2 0.0 1.8 1 1 1 2 2 2 1 Acyltransferase DUF2197 PF09963.9 KFM80796.1 - 0.08 13.2 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF1170 PF06663.13 KFM80797.1 - 0.00049 19.9 1.6 0.00049 19.9 1.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1170) Daxx PF03344.15 KFM80797.1 - 0.00096 19.2 3.8 0.0037 17.3 3.8 2.1 1 0 0 1 1 1 1 Daxx N-terminal Rassf1C-interacting domain SH3_1 PF00018.28 KFM80798.1 - 4.1e-08 32.7 0.0 7.7e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM80798.1 - 0.00036 20.3 0.1 0.00074 19.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFM80798.1 - 0.022 15.0 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain HR1 PF02185.16 KFM80798.1 - 0.025 14.7 0.9 0.025 14.7 0.9 2.5 2 1 0 2 2 2 0 Hr1 repeat MerR-DNA-bind PF09278.11 KFM80798.1 - 0.026 15.1 0.8 0.1 13.1 0.8 2.1 1 0 0 1 1 1 0 MerR, DNA binding Herpes_UL14 PF03580.14 KFM80798.1 - 0.067 13.4 0.1 0.067 13.4 0.1 2.4 2 1 1 3 3 3 0 Herpesvirus UL14-like protein CorA PF01544.18 KFM80798.1 - 0.69 9.2 9.8 7.6 5.8 5.8 2.8 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein MnmE_helical PF12631.7 KFM80798.1 - 0.82 9.8 9.6 0.14 12.3 1.2 2.3 2 0 0 2 2 2 0 MnmE helical domain COG5 PF10392.9 KFM80798.1 - 2.1 8.5 8.5 0.2 11.8 0.4 2.7 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Lzipper-MIP1 PF14389.6 KFM80798.1 - 5.9 7.3 8.1 1.4 9.3 2.0 2.8 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Takusan PF04822.13 KFM80798.1 - 6.8 6.6 9.9 0.32 10.9 1.2 3.0 2 1 1 3 3 3 0 Takusan Uds1 PF15456.6 KFM80798.1 - 9.2 6.4 19.6 0.33 11.1 2.3 3.0 2 2 0 2 2 2 0 Up-regulated During Septation Peptidase_M16 PF00675.20 KFM80799.1 - 5.3e-50 169.3 0.0 9.2e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFM80799.1 - 1.2e-36 126.5 0.0 5.4e-36 124.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF725 PF05267.12 KFM80799.1 - 0.033 14.2 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF725) M16C_assoc PF08367.11 KFM80799.1 - 0.13 11.3 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase M16C associated I-set PF07679.16 KFM80800.1 - 9.8e-23 80.0 0.4 1.2e-14 54.2 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM80800.1 - 2.6e-18 66.4 1.3 5.6e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM80800.1 - 7.5e-16 58.2 0.1 7.7e-11 42.2 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM80800.1 - 2.4e-13 50.1 0.3 1.1e-08 35.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFM80800.1 - 2.8e-05 24.4 0.2 0.00014 22.2 0.1 2.1 1 1 2 3 3 3 1 Immunoglobulin C1-set domain C2-set_2 PF08205.12 KFM80800.1 - 0.0009 19.3 1.0 0.55 10.3 0.1 2.6 2 1 1 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM80800.1 - 0.003 17.7 0.6 0.21 11.8 0.3 2.3 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM80800.1 - 0.016 14.7 0.0 0.088 12.4 0.0 2.1 3 0 0 3 3 3 0 Immunoglobulin domain V-set_CD47 PF08204.11 KFM80800.1 - 0.024 14.6 0.2 0.044 13.8 0.2 1.6 1 1 0 1 1 1 0 CD47 immunoglobulin-like domain TMEM132D_C PF15706.5 KFM80803.1 - 0.0089 15.8 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EphA2_TM PF14575.6 KFM80803.1 - 0.03 15.2 0.0 0.033 15.1 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KFM80803.1 - 0.035 14.0 1.1 0.045 13.6 1.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Chordopox_A13L PF05961.11 KFM80803.1 - 0.041 14.1 3.2 0.077 13.2 3.2 1.5 1 1 0 1 1 1 0 Chordopoxvirus A13L protein Sensor_TM1 PF13755.6 KFM80803.1 - 0.058 13.1 0.3 0.085 12.6 0.3 1.2 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain ASFV_J13L PF05568.11 KFM80803.1 - 0.062 13.1 0.1 0.069 12.9 0.1 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Stevor PF17410.2 KFM80803.1 - 0.21 11.1 1.6 0.26 10.8 1.6 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame FixQ PF05545.11 KFM80803.1 - 0.21 11.6 0.7 0.42 10.6 0.2 1.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Laminin_EGF PF00053.24 KFM80806.1 - 1.3e-20 73.2 27.1 2.4e-12 46.8 15.1 2.1 2 0 0 2 2 2 2 Laminin EGF domain EGF_2 PF07974.13 KFM80806.1 - 0.021 15.2 7.8 0.021 15.2 7.8 4.1 3 2 1 4 4 4 0 EGF-like domain Ephrin_rec_like PF07699.13 KFM80806.1 - 6.2 6.7 25.0 0.4 10.5 1.4 3.5 1 1 2 3 3 3 0 Putative ephrin-receptor like Laminin_N PF00055.17 KFM80807.1 - 5.2e-70 235.7 0.0 5.2e-70 235.7 0.0 1.8 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFM80807.1 - 8.8e-08 32.2 12.8 8.8e-08 32.2 12.8 2.4 2 1 0 2 2 2 1 Laminin EGF domain F5_F8_type_C PF00754.25 KFM80807.1 - 0.00072 19.7 0.0 0.0017 18.5 0.0 1.5 2 0 0 2 2 2 1 F5/8 type C domain hEGF PF12661.7 KFM80807.1 - 3.9 8.3 8.3 1.1 10.0 3.7 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF Metallothi_Euk2 PF12809.7 KFM80807.1 - 5.3 7.4 16.7 6.9 7.0 8.7 2.8 2 0 0 2 2 2 0 Eukaryotic metallothionein GTP_EFTU PF00009.27 KFM80808.1 - 1.1e-57 194.7 0.8 1.6e-57 194.2 0.8 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFM80808.1 - 4.2e-14 52.8 0.2 9.1e-14 51.7 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFM80808.1 - 4.7e-14 52.5 2.2 1.1e-13 51.3 2.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM80808.1 - 0.00017 21.7 0.2 0.00038 20.5 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4271 PF14093.6 KFM80809.1 - 0.00043 20.3 3.1 0.00061 19.8 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) AflR PF08493.10 KFM80809.1 - 0.18 11.3 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Acetyltransf_1 PF00583.25 KFM80810.1 - 1.9e-10 41.0 0.0 4.6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM80810.1 - 3.1e-09 36.8 0.0 7.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM80810.1 - 2.4e-08 34.3 0.0 4.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD PF00628.29 KFM80810.1 - 8.8e-05 22.3 5.4 0.00018 21.3 5.4 1.6 1 0 0 1 1 1 1 PHD-finger Acetyltransf_9 PF13527.7 KFM80810.1 - 0.00024 21.2 0.1 0.00054 20.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KFM80810.1 - 0.002 17.8 0.8 0.0062 16.1 0.0 2.0 2 0 0 2 2 2 1 GNAT acetyltransferase PHD_4 PF16866.5 KFM80810.1 - 0.084 13.0 4.1 0.38 10.9 4.1 2.1 1 1 0 1 1 1 0 PHD-finger Acetyltransf_13 PF13880.6 KFM80810.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Peptidase_A17 PF05380.13 KFM80816.1 - 2e-21 76.7 0.0 2.2e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Pao retrotransposon peptidase zf-CCCH PF00642.24 KFM80817.1 - 1.6e-06 27.9 1.6 3.4e-06 26.8 1.6 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFM80817.1 - 9.5e-06 25.3 5.0 1.8e-05 24.4 5.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFM80817.1 - 0.0001 22.2 7.1 0.00021 21.3 7.1 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KFM80817.1 - 0.003 18.2 0.0 0.003 18.2 0.0 3.0 2 1 1 3 3 3 1 Torus domain CH PF00307.31 KFM80818.1 - 3.1e-40 136.7 3.6 4.3e-24 84.8 2.4 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM80818.1 - 1.8e-11 43.7 0.3 6.9e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KFM80818.1 - 0.023 14.8 0.1 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 CH-like domain in sperm protein Filamin PF00630.19 KFM80819.1 - 2e-261 847.6 53.8 2.3e-16 60.5 0.0 24.5 24 0 0 24 24 24 24 Filamin/ABP280 repeat DUF5060 PF16586.5 KFM80819.1 - 1.4e-13 50.9 0.1 1.5 9.2 0.0 12.5 15 0 0 15 15 14 1 Domain of unknown function (DUF5060) YtkA PF13115.6 KFM80819.1 - 9.6e-10 38.9 1.5 0.33 11.6 0.0 9.3 9 0 0 9 9 9 2 YtkA-like Invasin_D3 PF09134.10 KFM80819.1 - 4.7e-08 33.2 12.5 0.07 13.4 0.1 11.1 13 1 1 14 14 14 1 Invasin, domain 3 Big_3_5 PF16640.5 KFM80819.1 - 2.9e-06 27.4 21.2 4.9 7.4 0.0 11.9 13 1 1 14 14 12 2 Bacterial Ig-like domain (group 3) PPC PF04151.15 KFM80819.1 - 5.7e-06 27.3 0.2 6.6 7.9 0.0 6.9 6 0 0 6 6 6 1 Bacterial pre-peptidase C-terminal domain Y_Y_Y PF07495.13 KFM80819.1 - 1.2e-05 25.2 6.0 10 6.2 0.0 7.6 8 1 1 9 9 9 1 Y_Y_Y domain Receptor_IA-2 PF11548.8 KFM80819.1 - 0.0059 16.6 1.8 0.015 15.3 0.1 2.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase receptor IA-2 CopC PF04234.12 KFM80819.1 - 0.023 15.7 0.9 57 4.8 0.0 6.8 8 2 0 8 8 6 0 CopC domain CarboxypepD_reg PF13620.6 KFM80819.1 - 0.026 14.8 19.8 4.9 7.5 0.0 10.1 11 0 0 11 11 9 0 Carboxypeptidase regulatory-like domain EMP24_GP25L PF01105.24 KFM80819.1 - 0.029 14.3 4.5 65 3.4 0.0 6.3 7 0 0 7 7 7 0 emp24/gp25L/p24 family/GOLD Peptidase_C42 PF05533.12 KFM80819.1 - 0.031 14.3 0.0 0.32 11.1 0.0 2.6 2 0 0 2 2 2 0 Beet yellows virus-type papain-like endopeptidase C42 A2M_BRD PF07703.14 KFM80819.1 - 0.083 13.2 8.4 29 5.0 0.2 5.6 3 2 0 3 3 3 0 Alpha-2-macroglobulin bait region domain ASH PF15780.5 KFM80819.1 - 0.26 11.5 3.8 26 5.1 0.2 5.5 5 0 0 5 5 5 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TIG PF01833.24 KFM80819.1 - 0.34 11.0 28.9 2.2 8.4 3.4 10.5 11 1 1 12 12 10 0 IPT/TIG domain Peptidase_C1 PF00112.23 KFM80821.1 - 2e-84 283.1 2.9 2.7e-84 282.6 2.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM80821.1 - 1e-12 48.3 1.1 1.7e-12 47.6 1.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM80821.1 - 6.7e-05 21.8 1.5 0.014 14.2 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Sirohm_synth_C PF14823.6 KFM80821.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal CRAL_TRIO PF00650.20 KFM80822.1 - 5.3e-27 94.5 0.0 8.6e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM80822.1 - 0.015 15.5 1.7 0.053 13.7 1.7 2.1 1 1 0 1 1 1 0 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM80822.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain PX PF00787.24 KFM80823.1 - 1.8e-22 79.5 0.2 3.5e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 PX domain DUF4736 PF15883.5 KFM80823.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) Pyridoxal_deC PF00282.19 KFM80824.1 - 4.9e-25 88.0 0.0 7.6e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFM80824.1 - 3.2e-10 39.5 0.0 9.2e-09 34.7 0.0 2.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFM80824.1 - 0.0047 16.3 0.2 0.0073 15.6 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFM80824.1 - 0.03 12.8 0.0 0.056 12.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF2367 PF10164.9 KFM80824.1 - 0.15 12.6 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Ras PF00071.22 KFM80826.1 - 5.4e-54 182.2 0.0 6e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM80826.1 - 1.5e-21 76.9 0.0 1.8e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM80826.1 - 5.3e-09 35.8 0.1 6.5e-09 35.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM80826.1 - 3.6e-07 29.9 0.1 1.1e-06 28.3 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM80826.1 - 0.00021 21.4 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM80826.1 - 0.00066 19.6 0.6 0.7 9.8 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFM80826.1 - 0.0071 15.7 0.2 0.0086 15.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFM80826.1 - 0.019 14.8 0.6 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFM80826.1 - 0.1 12.9 0.1 0.18 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 KFM80826.1 - 0.17 11.9 0.1 0.33 11.0 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thioredoxin PF00085.20 KFM80827.1 - 6.2e-91 299.2 0.7 2.1e-29 101.5 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KFM80827.1 - 1.3e-29 103.4 9.6 2.5e-20 73.2 4.7 4.3 4 0 0 4 4 4 4 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KFM80827.1 - 2.4e-16 60.1 4.1 0.00014 22.2 0.2 5.0 4 3 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM80827.1 - 2.5e-15 56.6 0.1 0.013 15.9 0.0 5.8 3 2 2 5 5 5 4 Thioredoxin-like Thioredoxin_7 PF13899.6 KFM80827.1 - 9.3e-14 51.4 0.0 0.00097 19.3 0.0 3.8 3 0 0 3 3 3 3 Thioredoxin-like Calsequestrin PF01216.17 KFM80827.1 - 2.3e-13 50.0 2.9 4.2e-07 29.3 2.5 4.0 1 1 1 2 2 2 2 Calsequestrin OST3_OST6 PF04756.13 KFM80827.1 - 2.6e-11 43.4 0.1 0.00022 20.7 0.0 4.4 3 2 2 5 5 5 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFM80827.1 - 4.2e-10 39.6 1.7 0.017 15.1 0.0 4.7 3 2 2 5 5 5 3 AhpC/TSA family Redoxin PF08534.10 KFM80827.1 - 1.1e-06 28.4 0.7 0.68 9.6 0.0 4.6 5 0 0 5 5 5 1 Redoxin Thioredoxin_4 PF13462.6 KFM80827.1 - 6.2e-05 23.2 4.0 0.21 11.8 0.1 4.1 3 1 0 4 4 4 2 Thioredoxin HyaE PF07449.11 KFM80827.1 - 0.00019 21.4 0.0 1.4 8.9 0.0 3.4 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KFM80827.1 - 0.00036 20.4 0.0 2.6 7.8 0.0 3.4 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KFM80827.1 - 0.00084 19.1 0.1 0.8 9.5 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin DSBA PF01323.20 KFM80827.1 - 0.0022 17.8 0.2 23 4.7 0.0 4.4 3 2 1 4 4 4 0 DSBA-like thioredoxin domain DUF3228 PF11539.8 KFM80827.1 - 0.03 13.9 0.0 4.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3228) Thioredoxin_5 PF13743.6 KFM80827.1 - 0.057 13.1 0.0 16 5.1 0.0 3.7 4 1 0 4 4 4 0 Thioredoxin MGS PF02142.22 KFM80829.1 - 0.12 12.6 0.1 0.22 11.7 0.1 1.7 1 1 0 1 1 1 0 MGS-like domain AKAP7_NLS PF10469.9 KFM80831.1 - 1e-32 113.7 0.0 1.4e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain MJ1316 PF04457.12 KFM80831.1 - 6.9e-25 87.6 0.1 1.7e-24 86.4 0.1 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain 2_5_RNA_ligase2 PF13563.6 KFM80831.1 - 1.3e-10 41.4 0.0 1.9e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KFM80831.1 - 3.7e-06 27.0 0.0 0.00091 19.4 0.0 2.3 1 1 1 2 2 2 2 LigT like Phosphoesterase IRS PF02174.17 KFM80832.1 - 7.5e-27 93.1 0.0 1.8e-26 91.9 0.0 1.6 2 0 0 2 2 2 1 PTB domain (IRS-1 type) PH PF00169.29 KFM80832.1 - 1.6e-05 25.4 0.1 3.6e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM80832.1 - 0.0018 18.7 1.7 0.0056 17.1 0.5 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain UNC-93 PF05978.16 KFM80834.1 - 1.1e-11 44.7 7.7 1.1e-11 44.7 7.7 3.4 2 1 1 3 3 3 2 Ion channel regulatory protein UNC-93 fn3 PF00041.21 KFM80836.1 - 3.7e-33 113.7 7.3 1.3e-18 67.1 0.8 3.1 4 0 0 4 4 4 2 Fibronectin type III domain I-set PF07679.16 KFM80836.1 - 1e-30 105.6 0.5 1e-16 60.8 0.0 3.0 4 0 0 4 4 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM80836.1 - 9.2e-28 96.7 0.8 1.6e-12 47.9 0.1 3.8 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 KFM80836.1 - 8.2e-22 77.2 0.3 9.4e-10 38.5 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM80836.1 - 9.7e-17 61.1 0.0 2.3e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM80836.1 - 1.5e-13 50.8 2.1 0.00011 22.3 0.0 4.9 3 1 1 4 4 4 2 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFM80836.1 - 7.3e-07 29.7 5.8 0.00052 20.5 0.6 4.1 3 2 0 3 3 2 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM80836.1 - 2e-06 28.0 0.0 0.0047 17.2 0.0 3.0 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Ig_6 PF18452.1 KFM80836.1 - 0.00011 21.7 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain DUF2369 PF10179.9 KFM80836.1 - 0.0023 18.2 0.0 0.015 15.6 0.0 2.3 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) Receptor_2B4 PF11465.8 KFM80836.1 - 0.0026 17.9 0.4 3.5 7.9 0.0 3.8 3 1 1 4 4 4 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 KFM80836.1 - 0.0044 17.1 0.1 0.63 10.1 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KFM80836.1 - 0.017 15.1 0.0 0.73 9.8 0.0 2.3 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFM80836.1 - 0.02 14.6 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFM80836.1 - 0.025 14.6 0.0 2 8.5 0.0 3.4 4 1 0 4 4 4 0 C17orf99 Ig domain C1-set PF07654.15 KFM80836.1 - 0.14 12.5 0.4 0.81 10.1 0.0 2.3 3 0 0 3 3 2 0 Immunoglobulin C1-set domain Cpn60_TCP1 PF00118.24 KFM80838.1 - 3.9e-158 527.1 12.1 4.4e-158 526.9 12.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SAS-6_N PF16531.5 KFM80839.1 - 6.7e-16 58.7 0.4 1e-15 58.1 0.4 1.3 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal SlyX PF04102.12 KFM80840.1 - 0.0006 20.4 18.2 0.19 12.4 3.2 3.4 2 1 1 3 3 3 2 SlyX Atg14 PF10186.9 KFM80840.1 - 0.0039 16.3 12.1 0.0039 16.3 12.1 2.2 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF730 PF05325.11 KFM80840.1 - 0.024 14.7 2.4 0.024 14.7 2.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF730) Pox_A_type_inc PF04508.12 KFM80840.1 - 0.028 14.3 2.8 0.28 11.1 0.1 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 KFM80840.1 - 0.19 11.8 34.3 0.033 14.2 13.8 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WD40_alt PF14077.6 KFM80840.1 - 0.21 11.5 0.3 0.21 11.5 0.3 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif AAA_13 PF13166.6 KFM80840.1 - 0.24 10.0 25.3 0.35 9.5 25.3 1.1 1 0 0 1 1 1 0 AAA domain IFT57 PF10498.9 KFM80840.1 - 0.28 10.1 23.0 0.43 9.5 23.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FAM76 PF16046.5 KFM80840.1 - 0.29 10.5 0.1 0.29 10.5 0.1 2.4 1 1 1 2 2 2 0 FAM76 protein Cob_adeno_trans PF01923.18 KFM80840.1 - 0.36 10.9 10.3 2.8 8.0 10.3 2.1 1 1 0 1 1 1 0 Cobalamin adenosyltransferase UPF0242 PF06785.11 KFM80840.1 - 0.99 9.5 32.1 6 6.9 31.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CP12 PF02672.15 KFM80840.1 - 1.1 10.0 6.0 0.7 10.7 0.2 2.7 2 0 0 2 2 2 0 CP12 domain FlaC_arch PF05377.11 KFM80840.1 - 1.6 9.2 26.9 0.52 10.7 0.5 4.4 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) ERM PF00769.19 KFM80840.1 - 2 8.2 26.9 68 3.2 26.9 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family SKA1 PF07160.12 KFM80840.1 - 2.3 8.0 29.3 0.063 13.1 0.9 3.1 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF724 PF05266.14 KFM80840.1 - 2.4 7.9 30.3 3.6 7.4 10.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HIP1_clath_bdg PF16515.5 KFM80840.1 - 2.7 8.7 27.4 6.2 7.5 5.2 3.2 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 USP8_interact PF08941.10 KFM80840.1 - 2.9 7.7 12.1 0.43 10.4 0.9 2.3 1 1 1 2 2 2 0 USP8 interacting DUF2968 PF11180.8 KFM80840.1 - 3 7.4 17.1 4.9 6.7 2.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) WEMBL PF05701.11 KFM80840.1 - 3.3 6.3 28.3 9.7 4.7 28.3 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light HMMR_N PF15905.5 KFM80840.1 - 4.2 6.8 35.0 6.4 6.1 33.4 1.8 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cast PF10174.9 KFM80840.1 - 4.4 5.4 32.4 7.8 4.6 32.4 1.3 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF1664 PF07889.12 KFM80840.1 - 4.6 7.3 20.2 0.23 11.5 5.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KFM80840.1 - 4.7 7.6 28.9 0.64 10.4 12.9 2.4 1 1 1 2 2 2 0 Fez1 KASH_CCD PF14662.6 KFM80840.1 - 5.9 6.7 35.1 3.9 7.3 32.0 1.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4200 PF13863.6 KFM80840.1 - 7.3 7.0 35.2 13 6.2 15.6 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 KFM80840.1 - 7.7 5.7 21.4 0.17 11.1 1.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 KFM80840.1 - 8.3 6.5 27.4 0.8 9.8 8.6 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Med9 PF07544.13 KFM80840.1 - 8.6 6.5 26.6 0.28 11.3 2.6 4.2 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 GCP_N_terminal PF17681.1 KFM80842.1 - 1.7e-21 77.2 0.4 2e-21 77.0 0.4 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFM80842.1 - 0.0017 17.9 0.4 0.0053 16.3 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal PNK3P PF08645.11 KFM80842.1 - 0.14 11.9 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase GCP_C_terminal PF04130.13 KFM80843.1 - 1.3e-44 153.0 7.6 1.4e-44 152.8 7.6 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal HMG_box PF00505.19 KFM80844.1 - 6.2e-25 87.4 15.6 3e-22 78.8 1.8 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM80844.1 - 2.5e-15 56.8 14.9 1.6e-13 51.0 1.7 3.3 3 1 0 3 3 3 2 HMG-box domain MlaC PF05494.12 KFM80844.1 - 0.061 13.1 0.7 0.096 12.4 0.1 1.5 2 0 0 2 2 2 0 MlaC protein FTCD_C PF04961.12 KFM80844.1 - 0.13 12.0 9.1 0.13 12.0 1.0 2.3 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase HMG_box_5 PF14887.6 KFM80844.1 - 0.47 10.5 12.3 0.5 10.4 3.1 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Mcm10 PF09332.11 KFM80844.1 - 0.8 9.1 17.3 0.97 8.8 17.3 1.0 1 0 0 1 1 1 0 Mcm10 replication factor Ank_2 PF12796.7 KFM80845.1 - 5.1e-42 142.4 5.1 1.6e-11 44.6 0.0 5.6 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM80845.1 - 3.2e-33 113.7 0.4 6.2e-08 33.0 0.0 8.2 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KFM80845.1 - 6.5e-28 95.9 0.8 0.0026 18.1 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KFM80845.1 - 1.5e-25 86.5 2.4 0.00035 20.8 0.0 9.3 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFM80845.1 - 1.7e-20 72.8 1.2 3.7e-05 23.9 0.0 5.3 4 1 1 5 5 5 5 Ankyrin repeats (many copies) TPR_2 PF07719.17 KFM80845.1 - 0.005 16.9 3.3 2.9 8.2 0.9 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM80845.1 - 0.26 11.2 1.2 24 4.9 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat V-set PF07686.17 KFM80846.1 - 3.1e-09 37.0 0.0 3.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM80846.1 - 1.7e-08 34.9 0.0 2.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM80846.1 - 5.1e-05 23.5 0.0 0.00019 21.7 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM80846.1 - 8.8e-05 22.5 0.1 0.00019 21.5 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM80846.1 - 0.00024 21.2 0.0 0.00054 20.1 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain V-set_2 PF15910.5 KFM80846.1 - 0.034 14.3 0.0 0.041 14.0 0.0 1.1 1 0 0 1 1 1 0 ICOS V-set domain Ig_4 PF16680.5 KFM80846.1 - 0.034 14.4 0.0 1.6 9.0 0.0 2.1 1 1 1 2 2 2 0 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFM80846.1 - 0.052 13.5 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain PDZ PF00595.24 KFM80847.1 - 0.02 15.2 0.1 0.022 15.1 0.1 1.1 1 0 0 1 1 1 0 PDZ domain Sorb PF02208.16 KFM80848.1 - 1.1e-13 50.7 0.1 2.1e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Sorbin homologous domain DUF5069 PF16798.5 KFM80848.1 - 0.13 12.4 0.1 0.42 10.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) SH3_1 PF00018.28 KFM80849.1 - 2.2e-17 62.4 0.0 7.2e-13 47.9 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KFM80849.1 - 8.3e-14 51.0 0.0 2e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFM80849.1 - 2.7e-11 43.1 0.0 1.1e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain Metallophos PF00149.28 KFM80850.1 - 1.1e-38 133.8 0.0 1.8e-38 133.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 KFM80850.1 - 0.0028 17.1 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) PTEN_C2 PF10409.9 KFM80850.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Histone PF00125.24 KFM80853.1 - 1.6e-10 41.5 0.1 1.7e-10 41.4 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM80853.1 - 0.00077 19.7 0.0 0.00079 19.7 0.0 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.11 KFM80853.1 - 0.029 14.5 0.0 0.031 14.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) TFIID_20kDa PF03847.13 KFM80853.1 - 0.058 13.9 0.0 0.064 13.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Brr6_like_C_C PF10104.9 KFM80854.1 - 0.45 10.3 4.3 0.57 10.0 4.3 1.3 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Phospholip_A2_2 PF05826.12 KFM80854.1 - 0.73 10.1 5.8 1.5 9.1 0.9 2.2 1 1 1 2 2 2 0 Phospholipase A2 SPRY PF00622.28 KFM80855.1 - 4.6e-22 78.4 0.2 5.5e-12 45.9 0.1 3.2 3 1 0 3 3 3 2 SPRY domain MULE PF10551.9 KFM80858.1 - 0.00016 22.0 0.0 0.00047 20.5 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Arrestin_C PF02752.22 KFM80858.1 - 0.066 13.7 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain SWIM PF04434.17 KFM80858.1 - 0.075 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 SWIM zinc finger RE_HaeIII PF09556.10 KFM80859.1 - 0.067 12.3 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease Serpin PF00079.20 KFM80860.1 - 3e-69 234.1 0.0 3.7e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Aminotran_3 PF00202.21 KFM80861.1 - 7.3e-113 377.3 0.0 8.8e-113 377.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III MGC-24 PF05283.11 KFM80861.1 - 0.091 13.2 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-CCCH_3 PF15663.5 KFM80862.1 - 8.9e-47 157.9 8.0 2.3e-46 156.6 8.0 1.6 1 0 0 1 1 1 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 KFM80862.1 - 0.015 15.3 0.9 0.015 15.3 0.9 3.8 4 0 0 4 4 4 0 Zinc finger domain zf-CCCH_2 PF14608.6 KFM80862.1 - 0.029 14.9 19.8 0.68 10.5 3.5 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zinc_ribbon_16 PF17034.5 KFM80864.1 - 2.6e-18 66.4 15.7 4.8e-18 65.6 15.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon like family Rep_fac-A_3 PF08661.11 KFM80865.1 - 5.2e-19 68.5 0.0 5.9e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Nucleos_tra2_C PF07662.13 KFM80866.1 - 3.6e-79 265.4 6.0 5.9e-79 264.7 6.0 1.3 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Gate PF07670.14 KFM80866.1 - 0.004 17.4 2.0 0.004 17.4 2.0 2.9 2 1 1 3 3 3 1 Nucleoside recognition DUF764 PF05561.11 KFM80866.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) SHMT PF00464.19 KFM80866.1 - 0.077 11.6 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Nucleos_tra2_N PF01773.20 KFM80867.1 - 1.8e-25 89.4 2.8 1.8e-25 89.4 2.8 2.2 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Homeodomain PF00046.29 KFM80870.1 - 5.7e-22 77.3 9.4 1.1e-21 76.4 9.4 1.5 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFM80870.1 - 0.081 13.3 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeobox_KN PF05920.11 KFM80870.1 - 0.12 12.3 0.7 0.25 11.3 0.7 1.5 1 0 0 1 1 1 0 Homeobox KN domain SPX PF03105.19 KFM80870.1 - 1.1 9.1 17.2 1.4 8.7 17.2 1.3 1 0 0 1 1 1 0 SPX domain PARM PF17061.5 KFM80870.1 - 1.7 8.7 19.6 2.2 8.4 19.6 1.2 1 0 0 1 1 1 0 PARM Ndc1_Nup PF09531.10 KFM80870.1 - 2.2 6.9 11.3 2.7 6.6 11.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nucleo_P87 PF07267.11 KFM80870.1 - 5.9 5.6 9.8 7.4 5.3 9.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MFS_1 PF07690.16 KFM80874.1 - 2.1e-35 122.3 39.3 5.7e-34 117.6 38.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM80874.1 - 1.5e-05 24.1 36.6 0.00061 18.8 37.4 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter ESSS PF10183.9 KFM80874.1 - 0.19 12.0 0.5 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF92 PF01940.16 KFM80875.1 - 1.4e-13 50.8 0.5 1.9e-13 50.4 0.5 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 zf-LITAF-like PF10601.9 KFM80875.1 - 0.058 13.7 0.1 0.058 13.7 0.1 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF962 PF06127.11 KFM80875.1 - 0.066 13.3 2.4 1.5 9.0 2.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Jiraiya PF15038.6 KFM80875.1 - 1.6 8.1 9.8 3.9 6.9 9.8 1.7 1 1 0 1 1 1 0 Jiraiya NMT_C PF02799.15 KFM80876.1 - 1.1e-77 260.3 0.6 1.6e-77 259.7 0.1 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KFM80876.1 - 7.7e-76 253.4 0.0 2e-75 252.0 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KFM80876.1 - 0.00011 22.4 0.0 0.001 19.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFM80876.1 - 0.0063 16.6 0.0 0.37 10.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ABC_tran PF00005.27 KFM80877.1 - 3.3e-53 179.9 0.1 2e-28 99.6 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFM80877.1 - 5.1e-38 131.3 13.1 8.8e-38 130.5 13.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KFM80877.1 - 2.3e-09 37.0 2.6 0.022 14.2 0.1 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KFM80877.1 - 3.8e-06 26.3 0.1 0.00041 19.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 KFM80877.1 - 1.2e-05 25.3 1.0 0.16 12.1 0.1 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 KFM80877.1 - 0.00075 19.1 0.1 0.37 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFM80877.1 - 0.00079 19.1 0.4 1.2 9.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM80877.1 - 0.0012 19.2 3.3 0.87 10.0 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFM80877.1 - 0.0015 18.5 0.3 0.93 9.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KFM80877.1 - 0.0017 18.3 0.3 1.8 8.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFM80877.1 - 0.013 15.7 0.8 8.6 6.6 0.4 3.5 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KFM80877.1 - 0.014 15.4 4.3 0.56 10.2 0.0 2.9 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 KFM80877.1 - 0.035 14.6 1.1 9.3 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KFM80877.1 - 0.037 13.8 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 KFM80877.1 - 0.037 13.2 0.2 7.5 5.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KFM80877.1 - 0.047 13.2 0.2 8.4 5.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 KFM80877.1 - 0.066 12.2 2.1 4.8 6.1 0.4 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KFM80877.1 - 0.089 12.9 0.1 0.089 12.9 0.1 3.2 4 0 0 4 4 4 0 Helicase HerA, central domain Dala_Dala_lig_N PF01820.21 KFM80877.1 - 0.17 12.3 0.1 10 6.7 0.0 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus IstB_IS21 PF01695.17 KFM80877.1 - 0.24 11.1 1.8 3.7 7.2 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF2075 PF09848.9 KFM80877.1 - 0.35 10.0 1.2 20 4.3 0.1 2.9 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KFM80877.1 - 0.76 9.5 4.8 11 5.7 0.5 3.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KFM80877.1 - 1.7 7.7 4.6 22 4.1 0.3 3.1 3 0 0 3 3 3 0 NB-ARC domain PRRSV_2b PF07069.11 KFM80879.1 - 0.015 15.8 5.1 0.017 15.6 5.1 1.3 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b Cadherin PF00028.17 KFM80881.1 - 1.1e-72 240.5 8.4 4.4e-18 65.5 0.3 5.0 5 0 0 5 5 5 4 Cadherin domain Cadherin_3 PF16184.5 KFM80881.1 - 1.4e-07 31.5 2.2 0.55 10.3 0.0 5.0 5 0 0 5 5 5 3 Cadherin-like Cadherin_2 PF08266.12 KFM80881.1 - 3.5e-05 23.6 0.0 0.036 13.9 0.0 3.8 4 0 0 4 4 4 1 Cadherin-like PepSY PF03413.19 KFM80881.1 - 0.026 15.1 6.0 38 4.9 0.1 5.4 6 1 1 7 7 7 0 Peptidase propeptide and YPEB domain Cadherin_4 PF17803.1 KFM80881.1 - 0.073 13.7 20.8 0.24 12.1 3.1 4.8 4 0 0 4 4 4 0 Bacterial cadherin-like domain DUF3364 PF11844.8 KFM80881.1 - 0.16 12.2 0.1 28 5.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3364) Sarcoglycan_1 PF04790.13 KFM80881.1 - 0.22 10.8 0.0 0.48 9.7 0.0 1.6 1 1 0 1 1 1 0 Sarcoglycan complex subunit protein Cadherin PF00028.17 KFM80882.1 - 0.0035 17.7 0.0 0.0037 17.7 0.0 1.0 1 0 0 1 1 1 1 Cadherin domain PEP-utilizers PF00391.23 KFM80885.1 - 6.1e-07 29.1 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain zf-H2C2_2 PF13465.6 KFM80886.1 - 8.1e-73 237.8 71.2 6.6e-09 35.8 0.2 12.1 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80886.1 - 4.4e-61 200.1 83.0 8.1e-07 29.2 2.0 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80886.1 - 4.4e-47 154.7 78.4 7.5e-05 23.2 1.3 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM80886.1 - 4.9e-31 106.2 78.3 0.0002 21.6 2.0 11.9 11 1 0 11 11 11 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM80886.1 - 1.5e-26 91.9 64.9 0.0024 17.8 0.1 11.3 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM80886.1 - 5.9e-22 77.4 56.5 0.00063 20.0 3.6 11.6 10 1 1 11 11 11 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM80886.1 - 1.4e-18 66.3 49.7 0.033 13.9 0.4 11.3 11 0 0 11 11 11 8 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM80886.1 - 4.3e-11 42.7 40.0 0.066 13.3 0.2 10.4 9 2 2 11 11 11 3 Sec23/Sec24 zinc finger BolA PF01722.18 KFM80886.1 - 3.1e-09 37.0 15.4 0.015 15.6 0.1 6.5 2 2 3 6 6 6 4 BolA-like protein zf-C2H2_9 PF16293.5 KFM80886.1 - 7.6e-09 35.3 45.6 0.69 9.8 1.8 10.1 2 2 8 10 10 10 3 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM80886.1 - 3.6e-08 33.1 19.6 0.68 9.8 0.1 8.4 2 2 7 9 9 9 3 GAGA factor ADK_lid PF05191.14 KFM80886.1 - 7.3e-08 32.3 37.5 0.2 11.7 0.9 7.6 6 2 0 6 6 6 5 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM80886.1 - 1.3e-07 31.6 36.9 1.9 8.7 0.0 10.6 11 0 0 11 11 11 3 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFM80886.1 - 3.1e-07 30.1 42.3 0.0098 15.8 0.1 10.3 11 0 0 11 11 11 3 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFM80886.1 - 1.2e-06 28.7 66.8 0.31 11.4 1.0 10.5 1 1 10 11 11 11 4 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 KFM80886.1 - 6.7e-06 26.1 50.2 0.9 9.7 0.2 10.4 10 1 1 11 11 10 2 DBF zinc finger DUF952 PF06108.12 KFM80886.1 - 5e-05 23.2 1.1 4.3 7.4 0.0 4.9 1 1 6 7 7 7 1 Protein of unknown function (DUF952) zf_UBZ PF18439.1 KFM80886.1 - 0.00046 19.7 50.8 3.2 7.4 0.2 11.1 11 0 0 11 11 11 2 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 KFM80886.1 - 0.0014 18.5 39.6 2.6 8.0 0.7 10.5 11 0 0 11 11 11 1 Prokaryotic RING finger family 1 zf-MYST PF17772.1 KFM80886.1 - 0.0025 17.4 47.0 0.94 9.1 0.7 10.2 3 3 8 11 11 11 3 MYST family zinc finger domain zf-BED PF02892.15 KFM80886.1 - 0.0025 17.8 69.8 0.068 13.2 1.2 10.2 1 1 9 10 10 10 3 BED zinc finger C5HCH PF17982.1 KFM80886.1 - 0.0025 17.9 45.1 4.8 7.4 0.4 10.2 8 2 2 11 11 11 1 NSD Cys-His rich domain FYVE PF01363.21 KFM80886.1 - 0.0051 16.9 56.9 1.1 9.5 9.4 7.2 2 1 5 7 7 7 3 FYVE zinc finger zf-CHCC PF10276.9 KFM80886.1 - 0.017 15.2 17.5 25 5.0 0.1 8.9 11 0 0 11 11 10 0 Zinc-finger domain Zn-ribbon_8 PF09723.10 KFM80886.1 - 0.018 15.1 39.1 1.5 9.0 0.3 7.4 4 3 4 8 8 8 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFM80886.1 - 0.028 14.2 51.8 0.66 9.8 0.2 10.3 11 0 0 11 11 11 0 zinc-finger C2H2-type TRAF6_Z2 PF18048.1 KFM80886.1 - 0.032 14.3 28.9 0.86 9.8 0.4 8.8 10 0 0 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_15 PF17032.5 KFM80886.1 - 0.047 14.4 41.4 1.1 10.0 2.2 5.8 1 1 5 7 7 7 0 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM80886.1 - 0.39 10.8 40.6 12 6.1 9.2 4.7 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type PqqA PF08042.11 KFM80886.1 - 0.42 10.7 1.9 4.1e+02 1.3 0.0 4.9 5 0 0 5 5 5 0 PqqA family zf-HIT PF04438.16 KFM80886.1 - 0.43 10.5 57.0 2.4 8.1 1.5 10.8 11 0 0 11 11 11 0 HIT zinc finger YyzF PF14116.6 KFM80886.1 - 0.69 10.0 34.5 32 4.7 0.1 10.3 10 1 1 11 11 11 0 YyzF-like protein XPA_N PF01286.18 KFM80886.1 - 3.9 7.6 40.1 11 6.2 0.1 10.2 11 0 0 11 11 11 0 XPA protein N-terminal zf-H2C2_2 PF13465.6 KFM80888.1 - 1e-69 228.1 73.7 1.3e-08 34.8 0.9 12.1 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80888.1 - 1.8e-54 179.2 91.8 8.4e-06 26.0 2.0 11.6 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80888.1 - 1.3e-38 128.3 88.8 0.00017 22.1 1.5 11.7 12 0 0 12 12 12 11 C2H2-type zinc finger zf-met PF12874.7 KFM80888.1 - 6.4e-18 64.5 69.4 0.0069 16.8 0.3 11.4 10 1 1 11 11 11 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM80888.1 - 2.9e-16 59.0 67.5 0.024 14.6 1.5 11.1 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM80888.1 - 2.4e-13 49.6 64.5 0.23 11.3 0.2 12.2 12 0 0 12 12 12 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM80888.1 - 3.7e-12 46.2 53.9 0.14 12.5 0.9 11.0 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM80888.1 - 4.3e-11 42.4 23.9 1.3 8.9 0.0 10.4 1 1 10 11 11 11 2 GAGA factor zf-C2H2_9 PF16293.5 KFM80888.1 - 4.7e-08 32.8 41.7 1.1 9.1 0.3 11.6 3 3 9 12 12 12 4 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFM80888.1 - 3.4e-06 27.0 30.8 1.5 8.9 0.0 10.1 9 1 2 11 11 11 1 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 KFM80888.1 - 1.1e-05 25.6 70.4 0.13 12.6 1.4 11.0 1 1 10 11 11 11 3 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFM80888.1 - 0.00023 21.4 13.3 0.8 10.0 0.4 6.1 1 1 3 5 5 5 1 BolA-like protein Ndufs5 PF10200.9 KFM80888.1 - 0.0021 18.3 13.0 2.1 8.6 0.1 6.5 1 1 7 8 8 8 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa TRAF6_Z2 PF18048.1 KFM80888.1 - 0.0096 16.0 44.5 4.6 7.4 0.4 10.5 11 0 0 11 11 11 4 TNF receptor-associated factor 6 zinc finger 2 ADK_lid PF05191.14 KFM80888.1 - 0.048 13.7 35.7 0.71 9.9 3.3 6.3 4 1 1 5 5 5 0 Adenylate kinase, active site lid zf-RRPl_C4 PF17026.5 KFM80888.1 - 0.29 11.3 40.4 0.45 10.7 3.7 5.0 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type YyzF PF14116.6 KFM80888.1 - 0.81 9.8 28.8 13 5.9 0.1 8.9 10 0 0 10 10 10 0 YyzF-like protein zinc_ribbon_15 PF17032.5 KFM80888.1 - 1.1 10.0 39.9 1.9 9.3 1.0 5.8 2 1 4 7 7 7 0 zinc-ribbon family C1_4 PF07975.12 KFM80888.1 - 3 8.2 46.4 0.14 12.4 2.9 6.3 4 2 2 6 6 6 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KFM80888.1 - 8.5 6.6 35.8 1.8 8.7 0.2 7.7 3 1 4 8 8 8 0 Zinc ribbon domain Chitin_bind_4 PF00379.23 KFM80890.1 - 1e-11 45.1 6.1 1.4e-11 44.7 6.1 1.2 1 0 0 1 1 1 1 Insect cuticle protein DUF2790 PF10976.8 KFM80890.1 - 0.044 13.8 0.1 0.65 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2790) DUF5437 PF17505.2 KFM80890.1 - 0.46 10.6 3.2 0.71 9.9 3.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5437) THAP PF05485.12 KFM80891.1 - 6e-17 62.4 2.5 1.4e-16 61.2 2.5 1.7 1 0 0 1 1 1 1 THAP domain CompInhib_SCIN PF11546.8 KFM80891.1 - 0.013 15.5 0.3 0.029 14.4 0.3 1.6 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN CorA PF01544.18 KFM80891.1 - 0.13 11.6 6.3 0.18 11.1 6.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ets PF00178.22 KFM80892.1 - 2.2e-36 124.2 0.4 3.7e-36 123.5 0.4 1.4 1 0 0 1 1 1 1 Ets-domain Abhydrolase_6 PF12697.7 KFM80893.1 - 2.4e-06 28.3 0.0 2.9e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KFM80894.1 - 1.7e-16 61.5 0.1 2.1e-16 61.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM80894.1 - 8.4e-11 41.6 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM80894.1 - 2.6e-09 37.1 0.0 3.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KFM80894.1 - 3.2e-06 27.0 0.1 5.5e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 KFM80894.1 - 0.0024 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.16 KFM80894.1 - 0.0044 16.8 0.4 2.1 8.1 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF900 PF05990.12 KFM80894.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 KFM80894.1 - 0.057 12.9 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 KFM80894.1 - 0.08 12.8 0.5 0.23 11.3 0.5 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KFM80894.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain ALGX PF16822.5 KFM80894.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Ras PF00071.22 KFM80895.1 - 3.5e-38 130.8 0.0 3.8e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM80895.1 - 2.5e-14 53.5 0.0 5e-14 52.6 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM80895.1 - 3.3e-06 26.7 0.0 4.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 KFM80895.1 - 0.00099 18.6 0.0 0.031 13.7 0.0 2.4 2 1 1 3 3 3 1 Bacterial TniB protein MMR_HSR1 PF01926.23 KFM80895.1 - 0.0062 16.6 0.0 0.0094 16.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KFM80895.1 - 0.021 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KFM80895.1 - 0.022 14.7 0.0 5.4 6.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KFM80895.1 - 0.04 13.9 0.0 1.8 8.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFM80895.1 - 0.087 13.2 0.0 0.17 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 KFM80895.1 - 0.088 12.5 0.1 0.09 12.5 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain IFT20 PF14931.6 KFM80896.1 - 1.7e-48 163.7 11.0 1.9e-48 163.5 11.0 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DUF737 PF05300.11 KFM80896.1 - 0.18 12.1 7.7 0.24 11.7 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Glyco_hydro_2_C PF02836.17 KFM80897.1 - 5.4e-76 255.6 0.2 1.7e-75 253.9 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFM80897.1 - 1.5e-23 83.6 0.5 4.2e-23 82.1 0.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KFM80897.1 - 3.1e-08 34.2 0.1 9e-08 32.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4434 PF14488.6 KFM80897.1 - 0.0048 16.9 0.0 0.023 14.7 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4434) LRR_8 PF13855.6 KFM80899.1 - 5e-14 51.8 8.4 4.8e-06 26.2 0.8 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_5 PF13306.6 KFM80899.1 - 4.9e-07 29.8 7.3 8.5e-07 29.0 3.6 2.4 1 1 2 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM80899.1 - 7.5e-06 26.2 5.1 0.0002 21.7 0.9 3.7 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM80899.1 - 4.4e-05 23.0 1.6 0.055 13.0 0.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat DUF1967 PF09269.11 KFM80900.1 - 0.0044 16.9 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) CRAL_TRIO PF00650.20 KFM80900.1 - 0.032 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 CRAL/TRIO domain Nudc_N PF14050.6 KFM80900.1 - 0.074 13.1 0.1 0.099 12.6 0.1 1.2 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. WW PF00397.26 KFM80903.1 - 5.4e-09 36.0 2.8 1.1e-08 35.0 2.8 1.6 1 0 0 1 1 1 1 WW domain Zip PF02535.22 KFM80904.1 - 3.8e-13 49.4 0.5 3.8e-13 49.4 0.5 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter ZIP4_domain PF18292.1 KFM80904.1 - 0.00012 22.1 2.5 0.12 12.3 0.0 3.1 3 0 0 3 3 3 2 Zinc transporter ZIP4 domain Zip PF02535.22 KFM80905.1 - 0.0017 17.7 0.2 0.0018 17.6 0.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Tubulin PF00091.25 KFM80908.1 - 1.6e-69 234.1 0.0 2.9e-69 233.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM80908.1 - 1.5e-43 148.0 0.2 2.4e-43 147.3 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFM80908.1 - 1.6e-05 25.2 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KFM80908.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KFM80908.1 - 0.022 13.9 0.1 0.053 12.7 0.0 1.6 2 0 0 2 2 2 0 Tubulin like Trypsin PF00089.26 KFM80909.1 - 1.2e-60 205.1 0.0 2.4e-60 204.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin Methyltransf_32 PF13679.6 KFM80911.1 - 4.3e-10 39.8 0.0 5e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM80911.1 - 0.0007 19.4 0.1 0.00097 19.0 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM80911.1 - 0.015 15.1 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KFM80911.1 - 0.028 13.5 0.1 0.057 12.5 0.0 1.5 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KFM80911.1 - 0.045 14.5 0.0 0.065 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPA PF17217.3 KFM80911.1 - 0.066 13.1 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 UPA domain MetW PF07021.12 KFM80911.1 - 0.084 12.4 0.1 0.16 11.6 0.1 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Ras PF00071.22 KFM80914.1 - 4.1e-21 75.3 0.0 4.5e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM80914.1 - 7e-19 68.2 0.0 8.7e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM80914.1 - 1.9e-08 34.0 0.0 2.1e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 KFM80914.1 - 0.004 16.9 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM80914.1 - 0.0063 16.8 0.0 0.038 14.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM80914.1 - 0.021 14.8 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KFM80914.1 - 0.028 14.1 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 KFM80914.1 - 0.04 14.3 0.1 0.086 13.3 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM80914.1 - 0.042 13.6 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain SRPRB PF09439.10 KFM80914.1 - 0.05 13.0 0.0 0.055 12.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFM80914.1 - 0.053 12.9 0.0 0.074 12.4 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM80914.1 - 0.058 13.5 0.1 0.13 12.4 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 KFM80914.1 - 0.062 12.8 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFM80914.1 - 0.065 12.6 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ras PF00071.22 KFM80915.1 - 1.3e-40 138.7 0.1 1.6e-40 138.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM80915.1 - 4.2e-22 78.6 0.1 7.6e-22 77.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM80915.1 - 1.1e-11 44.4 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM80915.1 - 9e-05 21.9 0.1 0.00013 21.4 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFM80915.1 - 0.00018 21.4 0.5 0.39 10.6 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 KFM80915.1 - 0.00087 19.1 0.1 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM80915.1 - 0.0052 16.8 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFM80915.1 - 0.013 15.9 0.1 0.039 14.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KFM80915.1 - 0.017 15.5 0.0 0.069 13.6 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KFM80915.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFM80915.1 - 0.032 14.6 0.0 0.049 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KFM80915.1 - 0.059 13.9 0.0 0.081 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFM80915.1 - 0.076 12.8 0.1 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFM80915.1 - 0.087 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFM80915.1 - 0.13 12.6 0.1 0.46 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFM80915.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Ras PF00071.22 KFM80917.1 - 1.4e-13 50.8 0.3 1.5e-13 50.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM80917.1 - 6.2e-11 42.6 0.2 6.9e-11 42.4 0.2 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM80917.1 - 1.7e-05 24.4 0.0 1.7e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_15 PF13175.6 KFM80917.1 - 0.012 15.4 0.1 0.012 15.4 0.1 1.0 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 KFM80917.1 - 0.017 14.8 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 KFM80917.1 - 0.018 14.8 0.2 0.023 14.4 0.2 1.3 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFM80917.1 - 0.029 14.5 0.1 0.031 14.3 0.1 1.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KFM80917.1 - 0.03 13.8 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KFM80917.1 - 0.032 13.8 0.2 0.032 13.8 0.2 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFM80917.1 - 0.042 14.4 0.0 0.048 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFM80917.1 - 0.058 13.1 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KFM80917.1 - 0.069 13.4 0.0 0.069 13.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM80917.1 - 0.096 12.6 0.1 0.096 12.6 0.1 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_14 PF13173.6 KFM80917.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM80917.1 - 0.18 11.6 0.5 0.28 10.9 0.3 1.5 1 1 0 1 1 1 0 P-loop containing region of AAA domain Zona_pellucida PF00100.23 KFM80918.1 - 2.5e-23 83.2 3.6 2.5e-23 83.2 3.6 2.3 2 1 1 3 3 3 1 Zona pellucida-like domain DUF4083 PF13314.6 KFM80918.1 - 0.15 12.1 0.2 0.32 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Phospholip_A2_1 PF00068.19 KFM80919.1 - 2.7e-17 63.3 8.5 5.5e-17 62.2 8.5 1.6 2 0 0 2 2 2 1 Phospholipase A2 UPF0239 PF06783.11 KFM80919.1 - 0.077 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Phospholip_A2_1 PF00068.19 KFM80920.1 - 0.00023 21.6 2.4 0.00026 21.4 2.4 1.3 1 0 0 1 1 1 1 Phospholipase A2 WD40 PF00400.32 KFM80921.1 - 4.2e-06 27.4 0.4 0.014 16.2 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM80921.1 - 7e-06 26.3 0.0 0.18 12.1 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Coilin_N PF15862.5 KFM80923.1 - 0.044 13.6 1.3 0.062 13.1 1.3 1.3 1 0 0 1 1 1 0 Coilin N-terminus CLIP_SPH_mas PF18398.1 KFM80923.1 - 0.071 13.5 2.1 0.1 13.0 1.0 1.8 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade VPS13_C PF16909.5 KFM80924.1 - 7e-26 91.1 0.7 1.3e-23 83.7 0.1 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 KFM80924.1 - 0.012 15.9 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain Syntaxin-6_N PF09177.11 KFM80929.1 - 0.12 12.9 0.8 0.37 11.4 0.8 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Ribosomal_L50 PF10501.9 KFM80931.1 - 0.1 12.7 0.8 6 7.1 0.1 2.4 2 0 0 2 2 2 0 Ribosomal subunit 39S Y_phosphatase PF00102.27 KFM80932.1 - 8.3e-77 257.9 0.4 1.3e-76 257.2 0.4 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFM80932.1 - 7.2e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFM80932.1 - 0.0001 22.3 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFM80932.1 - 0.0011 19.2 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Fibrinogen_C PF00147.18 KFM80933.1 - 2.1e-60 204.2 11.6 2.6e-60 204.0 11.6 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 KFM80934.1 - 4.7e-60 203.1 13.0 5.9e-60 202.8 13.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Pkinase_Tyr PF07714.17 KFM80935.1 - 2.1e-82 276.3 0.0 2.8e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM80935.1 - 1.1e-33 116.7 0.0 1.7e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 KFM80935.1 - 1.4e-17 63.7 3.6 2e-16 60.1 3.9 2.7 2 1 0 2 2 2 1 Kringle domain Fz PF01392.22 KFM80935.1 - 2.8e-10 40.8 4.7 4.8e-10 40.0 2.5 2.6 2 0 0 2 2 2 1 Fz domain Ins145_P3_rec PF08709.11 KFM80937.1 - 1.7e-64 216.9 0.5 1.9e-64 216.8 0.5 1.0 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 KFM80937.1 - 0.031 14.1 0.1 0.044 13.6 0.1 1.5 1 1 0 1 1 1 0 MIR domain RYDR_ITPR PF01365.21 KFM80938.1 - 3.3e-21 75.6 0.0 4.7e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 RIH domain LON_substr_bdg PF02190.16 KFM80938.1 - 0.024 14.5 0.3 0.029 14.3 0.3 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain RYDR_ITPR PF01365.21 KFM80939.1 - 4.4e-30 104.6 1.2 5.3e-30 104.4 1.2 1.1 1 0 0 1 1 1 1 RIH domain CCSMST1 PF15013.6 KFM80941.1 - 0.029 14.5 0.7 0.036 14.2 0.7 1.2 1 0 0 1 1 1 0 CCSMST1 family DUF2417 PF10329.9 KFM80941.1 - 2.4 7.5 7.4 2.5 7.4 7.4 1.0 1 0 0 1 1 1 0 Region of unknown function (DUF2417) RYDR_ITPR PF01365.21 KFM80942.1 - 4.5e-12 45.8 2.2 4.5e-12 45.8 2.2 2.2 3 0 0 3 3 3 1 RIH domain RE_R_Pab1 PF09522.10 KFM80942.1 - 0.03 14.4 0.1 0.1 12.7 0.1 1.9 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease Lambda_Bor PF06291.11 KFM80942.1 - 0.11 12.6 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Bor protein CENP-F_leu_zip PF10473.9 KFM80945.1 - 0.0012 18.9 0.3 0.0012 18.9 0.3 1.5 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RIH_assoc PF08454.11 KFM80946.1 - 6e-13 48.5 0.2 1.5e-12 47.3 0.2 1.7 1 0 0 1 1 1 1 RyR and IP3R Homology associated DUF1830 PF08865.11 KFM80946.1 - 0.08 13.0 0.2 0.22 11.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Ion_trans PF00520.31 KFM80947.1 - 1.1e-09 37.9 0.0 2.2e-09 36.9 0.0 1.5 2 0 0 2 2 2 1 Ion transport protein MscS_porin PF12795.7 KFM80947.1 - 0.0034 17.0 3.7 0.0051 16.4 3.7 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Sec2p PF06428.11 KFM80947.1 - 0.01 15.8 7.4 0.021 14.8 7.4 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Csm1_N PF18504.1 KFM80947.1 - 2.2 8.7 6.4 5.3 7.5 6.4 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain Filament PF00038.21 KFM80948.1 - 0.0017 18.0 15.2 0.0017 18.0 15.2 7.1 1 1 7 8 8 8 5 Intermediate filament protein Laminin_II PF06009.12 KFM80948.1 - 0.0039 17.2 5.4 0.0039 17.2 5.4 8.3 3 1 4 9 9 9 1 Laminin Domain II MBOAT PF03062.19 KFM80950.1 - 2.6e-06 27.1 12.8 3.5e-06 26.6 12.6 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family ASFV_360 PF01671.16 KFM80950.1 - 0.051 13.1 1.7 0.09 12.3 1.7 1.3 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein zf-H2C2_2 PF13465.6 KFM80951.1 - 1e-77 253.3 94.7 3.2e-08 33.6 1.3 12.8 14 0 0 14 14 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80951.1 - 3.4e-69 225.6 90.8 1.6e-06 28.2 0.6 12.9 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80951.1 - 8.8e-53 172.4 82.3 0.00015 22.3 0.4 13.2 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM80951.1 - 2.2e-20 72.4 53.2 0.044 14.1 0.2 13.2 13 0 0 13 13 13 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM80951.1 - 1.6e-16 59.9 72.5 0.0042 17.1 1.5 12.4 12 0 0 12 12 12 8 C2H2-type zinc finger zf-Di19 PF05605.12 KFM80951.1 - 5.8e-14 52.1 57.3 0.00034 20.9 3.1 8.5 3 3 5 9 9 9 6 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 KFM80951.1 - 3.9e-12 46.2 47.1 0.24 11.7 0.1 12.8 13 0 0 13 13 13 3 zinc-ribbon zf_UBZ PF18439.1 KFM80951.1 - 1.1e-11 44.0 40.1 0.76 9.4 0.1 12.7 13 0 0 13 13 13 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM80951.1 - 6.4e-10 39.0 46.3 0.027 14.6 0.6 8.5 4 2 7 11 11 10 7 Zinc ribbon domain HypA PF01155.19 KFM80951.1 - 8.3e-09 35.5 36.5 0.045 13.8 0.5 7.1 1 1 7 8 8 8 6 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 KFM80951.1 - 8.8e-08 32.8 44.7 0.067 13.9 0.6 7.0 2 2 5 7 7 7 5 zinc-ribbon family DUF3268 PF11672.8 KFM80951.1 - 2.2e-07 31.2 43.0 0.009 16.3 1.3 6.8 3 1 7 10 10 10 6 zinc-finger-containing domain OSTMP1 PF09777.9 KFM80951.1 - 1.4e-06 27.9 26.6 0.017 14.5 4.2 4.6 1 1 3 4 4 4 4 Osteopetrosis-associated transmembrane protein 1 precursor PyrI_C PF02748.15 KFM80951.1 - 1.1e-05 25.3 37.0 0.19 11.7 0.3 10.4 11 1 0 11 11 10 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.7 KFM80951.1 - 1.5e-05 25.3 52.6 0.12 12.7 2.4 9.5 1 1 7 9 9 9 3 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM80951.1 - 2e-05 24.6 46.4 2.2 8.5 0.1 12.4 13 0 0 13 13 13 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 KFM80951.1 - 3.1e-05 24.3 73.1 0.12 12.8 1.5 11.9 1 1 10 11 11 11 4 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KFM80951.1 - 7.7e-05 22.8 63.0 3 8.1 0.2 12.7 13 0 0 13 13 13 1 AN1-like Zinc finger zf-C2H2_3rep PF18868.1 KFM80951.1 - 0.00022 21.9 37.8 16 6.2 0.3 9.3 1 1 4 6 6 6 0 Zinc finger C2H2-type, 3 repeats IGPD PF00475.18 KFM80951.1 - 0.0039 17.5 2.3 7.5 6.9 0.0 4.9 2 2 3 6 6 6 0 Imidazoleglycerol-phosphate dehydratase Yop-YscD_ppl PF16693.5 KFM80951.1 - 0.0047 16.4 0.0 19 4.6 0.0 3.6 3 1 1 4 4 4 0 Inner membrane component of T3SS, periplasmic domain A_deaminase PF00962.22 KFM80951.1 - 0.0052 16.2 10.6 2 7.6 0.4 4.6 3 2 2 5 5 5 2 Adenosine/AMP deaminase zf-LYAR PF08790.11 KFM80951.1 - 0.0069 16.3 57.4 0.21 11.6 0.2 11.5 12 0 0 12 12 12 3 LYAR-type C2HC zinc finger Mg-por_mtran_C PF07109.11 KFM80951.1 - 0.015 15.6 0.0 26 5.2 0.0 4.1 4 0 0 4 4 4 0 Magnesium-protoporphyrin IX methyltransferase C-terminus zf-C2HC_2 PF13913.6 KFM80951.1 - 0.016 15.1 59.2 2.4 8.2 0.1 12.0 13 0 0 13 13 11 0 zinc-finger of a C2HC-type zf_C2H2_ZHX PF18387.1 KFM80951.1 - 0.017 14.8 70.5 1.6 8.4 0.4 11.7 3 1 10 13 13 12 0 Zinc-fingers and homeoboxes C2H2 finger domain Rpr2 PF04032.16 KFM80951.1 - 0.031 14.6 47.8 1.9 8.8 1.6 7.0 4 3 1 5 5 5 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-FCS PF06467.14 KFM80951.1 - 0.032 14.2 61.0 1 9.4 0.4 12.1 8 3 5 13 13 13 0 MYM-type Zinc finger with FCS sequence motif zf-BED PF02892.15 KFM80951.1 - 0.057 13.4 87.6 0.62 10.1 1.4 12.5 1 1 12 13 13 13 0 BED zinc finger RESP18 PF14948.6 KFM80951.1 - 0.062 13.6 0.0 20 5.6 0.0 2.4 2 0 0 2 2 2 0 RESP18 domain zf-C2H2_11 PF16622.5 KFM80951.1 - 0.077 12.8 0.3 0.077 12.8 0.3 11.0 13 0 0 13 13 11 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 KFM80951.1 - 0.12 12.3 48.5 3 7.8 0.0 11.9 13 0 0 13 13 13 0 zinc-ribbon domain XPA_N PF01286.18 KFM80951.1 - 0.17 11.9 42.6 26 5.0 0.2 12.1 13 0 0 13 13 13 0 XPA protein N-terminal Zn_ribbon_SprT PF17283.2 KFM80951.1 - 0.35 10.8 69.5 2.7 8.0 0.4 11.8 8 4 2 10 10 10 0 SprT-like zinc ribbon domain DUF4187 PF13821.6 KFM80951.1 - 0.38 10.6 16.8 24 4.8 0.0 7.8 8 1 1 9 9 8 0 Domain of unknown function (DUF4187) zf-CHCC PF10276.9 KFM80951.1 - 0.66 10.1 0.1 0.66 10.1 0.1 10.0 12 0 0 12 12 11 0 Zinc-finger domain zf-trcl PF13451.6 KFM80951.1 - 0.7 9.8 55.6 16 5.5 0.0 12.3 13 0 0 13 13 13 0 Probable zinc-ribbon domain zf_C2H2_13 PF18508.1 KFM80951.1 - 0.8 9.3 33.6 20 4.9 0.1 9.4 10 0 0 10 10 9 0 Zinc finger domain zf-MYST PF17772.1 KFM80951.1 - 0.83 9.3 43.7 3.6 7.3 0.5 11.1 6 5 6 12 12 12 0 MYST family zinc finger domain Acyltransf_C PF16076.5 KFM80951.1 - 1 9.5 6.1 44 4.3 0.2 5.1 4 2 1 5 5 5 0 Acyltransferase C-terminus YhfH PF14149.6 KFM80951.1 - 1.1 9.3 39.6 4.9 7.2 0.1 10.4 11 0 0 11 11 11 0 YhfH-like protein PknG_rubred PF16919.5 KFM80951.1 - 1.5 9.0 38.1 3.4 7.8 1.8 7.4 1 1 7 9 9 9 0 Protein kinase G rubredoxin domain zf-H2C2_2 PF13465.6 KFM80952.1 - 4.1e-73 238.8 86.3 9.8e-09 35.3 0.5 12.4 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80952.1 - 2.8e-58 191.2 85.2 1.3e-06 28.5 0.7 11.7 12 0 0 12 12 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80952.1 - 3.1e-43 142.7 78.5 0.00039 21.0 0.7 12.2 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM80952.1 - 2.6e-18 65.8 47.1 0.066 13.5 0.6 12.2 12 0 0 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM80952.1 - 3.3e-15 55.7 67.9 0.0053 16.7 0.6 11.1 11 0 0 11 11 11 7 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KFM80952.1 - 1.7e-08 34.6 44.5 4.4 7.6 0.1 12.0 12 0 0 12 12 12 3 zinc-ribbon zinc_ribbon_15 PF17032.5 KFM80952.1 - 1.4e-07 32.1 39.4 0.83 10.5 4.3 6.6 1 1 9 10 10 10 7 zinc-ribbon family HypA PF01155.19 KFM80952.1 - 7.1e-07 29.2 32.2 0.75 9.8 1.7 6.9 1 1 8 9 9 9 7 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KFM80952.1 - 7.5e-07 29.2 48.1 0.077 13.1 0.8 8.4 4 1 7 11 11 11 7 Zinc ribbon domain zf_UBZ PF18439.1 KFM80952.1 - 1.6e-06 27.6 36.7 5.2 6.7 0.0 10.7 12 0 0 12 12 10 3 Ubiquitin-Binding Zinc Finger OSTMP1 PF09777.9 KFM80952.1 - 8.5e-06 25.3 18.4 0.28 10.6 0.9 4.5 1 1 2 3 3 3 3 Osteopetrosis-associated transmembrane protein 1 precursor DUF3268 PF11672.8 KFM80952.1 - 2.1e-05 24.8 37.9 0.03 14.7 1.1 6.6 4 2 2 7 7 7 4 zinc-finger-containing domain zf-H2C2_5 PF13909.6 KFM80952.1 - 0.00046 19.9 4.8 0.0029 17.3 0.7 14.9 13 5 0 13 13 12 4 C2H2-type zinc-finger domain zf-AN1 PF01428.16 KFM80952.1 - 0.001 19.2 53.5 4 7.7 0.2 11.6 12 0 0 12 12 12 1 AN1-like Zinc finger C1_1 PF00130.22 KFM80952.1 - 0.0027 17.6 61.5 6.1 6.8 2.3 11.0 2 2 9 11 11 11 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HE PF16278.5 KFM80952.1 - 0.0027 18.1 65.1 0.26 11.8 1.4 10.8 2 1 9 11 11 11 4 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 KFM80952.1 - 0.004 17.0 39.6 0.41 10.6 0.1 10.5 9 2 2 11 11 11 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain A_deaminase PF00962.22 KFM80952.1 - 0.0045 16.4 15.9 0.54 9.5 1.3 5.1 2 2 3 5 5 5 2 Adenosine/AMP deaminase IGPD PF00475.18 KFM80952.1 - 0.0048 17.2 3.5 7.8 6.8 0.1 4.7 1 1 4 6 6 6 0 Imidazoleglycerol-phosphate dehydratase UPF0302 PF08864.10 KFM80952.1 - 0.0052 16.8 0.0 14 5.8 0.0 3.5 3 1 0 3 3 3 0 UPF0302 domain Yop-YscD_ppl PF16693.5 KFM80952.1 - 0.008 15.6 0.0 12 5.2 0.0 3.4 3 1 1 4 4 4 0 Inner membrane component of T3SS, periplasmic domain zf-C2H2_11 PF16622.5 KFM80952.1 - 0.0096 15.7 0.5 0.0096 15.7 0.5 10.4 12 0 0 12 12 11 1 zinc-finger C2H2-type XPA_N PF01286.18 KFM80952.1 - 0.013 15.5 41.2 21 5.2 0.0 11.0 12 0 0 12 12 11 0 XPA protein N-terminal zf-BED PF02892.15 KFM80952.1 - 0.013 15.5 77.5 0.099 12.7 1.2 11.5 1 1 11 12 12 12 0 BED zinc finger Rpr2 PF04032.16 KFM80952.1 - 0.059 13.7 39.9 3.3 8.1 0.3 6.3 4 3 0 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RESP18 PF14948.6 KFM80952.1 - 0.061 13.6 0.0 15 5.9 0.0 2.6 2 0 0 2 2 2 0 RESP18 domain ATPase-cat_bd PF12156.8 KFM80952.1 - 0.38 11.5 55.1 1.9 9.3 2.5 7.2 6 1 2 8 8 8 0 Putative metal-binding domain of cation transport ATPase zf-C2H2_2 PF12756.7 KFM80952.1 - 0.52 10.7 54.8 0.17 12.2 3.9 8.9 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFM80952.1 - 0.63 10.2 42.7 4.1 7.6 0.0 10.7 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.6 KFM80953.1 - 1.4e-91 297.2 133.4 1.6e-08 34.6 0.3 16.5 17 0 0 17 17 16 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM80953.1 - 3.2e-74 241.4 131.3 2.3e-06 27.7 2.6 16.2 16 0 0 16 16 16 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM80953.1 - 2e-58 189.9 119.6 0.00052 20.6 1.8 16.4 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM80953.1 - 4.6e-15 55.5 76.6 0.027 14.8 0.6 15.9 16 0 0 16 16 16 7 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KFM80953.1 - 3.3e-12 46.4 61.1 0.65 10.3 0.1 15.2 16 0 0 16 16 16 6 zinc-ribbon zf-C2H2_6 PF13912.6 KFM80953.1 - 3.5e-11 42.8 119.7 0.02 14.9 1.4 15.7 16 0 0 16 16 16 11 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFM80953.1 - 4.8e-10 40.1 48.5 0.38 11.5 0.3 8.6 1 1 7 9 9 9 7 zinc-ribbon family zf_UBZ PF18439.1 KFM80953.1 - 1.2e-07 31.2 52.5 1.5 8.5 0.0 15.1 16 0 0 16 16 16 4 Ubiquitin-Binding Zinc Finger HypA PF01155.19 KFM80953.1 - 3.6e-07 30.2 44.6 3.5 7.7 1.2 8.6 1 1 7 8 8 8 5 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KFM80953.1 - 1.8e-05 24.7 66.2 0.27 11.4 1.6 11.3 4 2 8 12 12 12 6 Zinc ribbon domain DUF3268 PF11672.8 KFM80953.1 - 2.3e-05 24.7 49.0 0.047 14.0 1.0 8.5 4 2 7 11 11 11 5 zinc-finger-containing domain OSTMP1 PF09777.9 KFM80953.1 - 0.00023 20.6 23.7 0.16 11.4 5.0 4.6 1 1 3 4 4 4 3 Osteopetrosis-associated transmembrane protein 1 precursor zf-AN1 PF01428.16 KFM80953.1 - 0.0022 18.1 74.5 3.7 7.8 0.7 15.7 16 0 0 16 16 16 2 AN1-like Zinc finger PyrI_C PF02748.15 KFM80953.1 - 0.0064 16.4 50.0 1.2 9.0 0.1 12.6 13 3 2 15 15 15 3 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.7 KFM80953.1 - 0.0073 16.6 3.9 0.0073 16.6 3.9 11.3 1 1 8 10 10 10 1 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KFM80953.1 - 0.038 13.9 0.1 0.038 13.9 0.1 12.4 14 0 0 14 14 14 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM80953.1 - 0.098 12.3 39.6 6.2 6.5 0.1 11.2 7 3 5 12 12 12 0 MYST family zinc finger domain zf-trcl PF13451.6 KFM80953.1 - 0.81 9.6 63.3 8.3 6.4 0.4 14.2 15 0 0 15 15 15 0 Probable zinc-ribbon domain PNK3P PF08645.11 KFM80954.1 - 4.1e-59 198.9 0.0 9.7e-59 197.7 0.0 1.7 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase FHA_2 PF17913.1 KFM80954.1 - 2.7e-30 104.4 0.1 6.2e-30 103.3 0.1 1.6 1 0 0 1 1 1 1 FHA domain AAA_33 PF13671.6 KFM80954.1 - 1.8e-18 67.1 0.0 1.2e-10 41.7 0.0 2.6 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KFM80954.1 - 0.032 13.5 0.0 2.4 7.4 0.0 2.5 1 1 1 2 2 2 0 Zeta toxin KTI12 PF08433.10 KFM80954.1 - 0.058 12.8 0.0 7.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Hydrolase_6 PF13344.6 KFM80954.1 - 0.09 12.9 0.0 27 5.0 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase AMP-binding PF00501.28 KFM80956.1 - 1e-21 77.1 0.0 1.1e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM80957.1 - 0.00033 20.5 4.8 0.00055 19.8 4.8 1.4 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Spond_N PF06468.13 KFM80957.1 - 0.12 12.5 3.6 0.21 11.7 3.6 1.3 1 0 0 1 1 1 0 Spondin_N 7tm_1 PF00001.21 KFM80958.1 - 0.23 10.7 1.3 0.28 10.4 0.7 1.4 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) HRG PF16954.5 KFM80959.1 - 0.00022 21.6 2.5 0.00022 21.6 2.5 2.8 2 2 0 2 2 2 1 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF4173 PF13777.6 KFM80959.1 - 0.00038 19.9 4.8 0.00048 19.6 4.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4173) DUF2417 PF10329.9 KFM80959.1 - 0.065 12.7 1.3 0.079 12.4 1.3 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Sdh_cyt PF01127.22 KFM80959.1 - 1.2 9.1 4.9 0.48 10.5 0.6 2.0 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PIG-P PF08510.12 KFM80959.1 - 4.1 7.4 6.5 6.8 6.6 0.9 2.4 2 1 0 2 2 2 0 PIG-P MCC-bdg_PDZ PF10506.9 KFM80960.1 - 3e-37 126.4 15.9 3.5e-26 91.0 4.2 6.3 5 1 1 6 6 6 2 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4763 PF15960.5 KFM80960.1 - 0.0025 17.2 8.7 0.0025 17.2 8.7 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF4763) HrpB7 PF09486.10 KFM80960.1 - 0.011 16.1 6.9 0.011 16.1 6.9 4.4 4 2 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) TMP_2 PF06791.13 KFM80960.1 - 0.45 10.1 5.6 31 4.1 4.9 2.5 2 0 0 2 2 2 0 Prophage tail length tape measure protein DASH_Dam1 PF08653.10 KFM80960.1 - 0.57 10.0 6.0 2.4 8.0 1.3 3.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 Atg14 PF10186.9 KFM80960.1 - 3 6.9 55.9 0.016 14.3 8.4 4.2 2 1 1 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pox_A_type_inc PF04508.12 KFM80960.1 - 8.2 6.5 15.2 2.4 8.1 0.5 5.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Innexin PF00876.18 KFM80961.1 - 2e-66 224.7 2.7 2.2e-66 224.5 2.7 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 KFM80962.1 - 2.3e-99 333.0 8.7 2.6e-99 332.9 8.7 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 KFM80963.1 - 1.7e-91 307.1 12.0 2e-91 306.9 12.0 1.0 1 0 0 1 1 1 1 Innexin Ni_hydr_CYTB PF01292.20 KFM80963.1 - 0.049 13.2 1.1 1.9 8.1 0.0 2.6 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 F-box PF00646.33 KFM80963.1 - 0.32 10.9 3.0 0.26 11.2 0.7 2.1 2 0 0 2 2 2 0 F-box domain Innexin PF00876.18 KFM80964.1 - 1.6e-95 320.4 11.2 1.9e-95 320.2 11.2 1.0 1 0 0 1 1 1 1 Innexin DJ-1_PfpI PF01965.24 KFM80966.1 - 2.1e-50 170.8 0.2 2.4e-50 170.6 0.2 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 KFM80966.1 - 0.0038 16.8 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 KFM80966.1 - 0.022 14.5 0.0 1.6 8.4 0.0 2.2 1 1 1 2 2 2 0 ThiJ/PfpI family-like VMA21 PF09446.10 KFM80967.1 - 0.031 14.4 0.7 0.047 13.8 0.7 1.2 1 0 0 1 1 1 0 VMA21-like domain Furin-like_2 PF15913.5 KFM80967.1 - 0.039 14.1 4.3 0.074 13.2 4.3 1.5 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 KFM80967.1 - 0.2 11.5 9.8 0.053 13.3 5.4 2.0 2 1 0 2 2 2 0 Growth factor receptor domain IV Voltage_CLC PF00654.20 KFM80969.1 - 4.3e-85 286.1 17.5 5.1e-85 285.8 17.5 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KFM80969.1 - 1.4e-13 51.0 0.7 7.8e-08 32.6 0.2 2.7 2 0 0 2 2 2 2 CBS domain LacI PF00356.21 KFM80969.1 - 2.4 8.0 7.2 0.36 10.7 0.5 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF4467 PF14729.6 KFM80970.1 - 9.2 6.7 10.8 27 5.2 1.5 3.8 3 0 0 3 3 3 0 Domain of unknown function with cystatin-like fold (DUF4467) RAB3GAP2_C PF14656.6 KFM80971.1 - 9.3e-53 179.4 0.3 1e-52 179.2 0.3 1.0 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_C PF14656.6 KFM80972.1 - 2.4e-20 72.3 2.9 2.6e-20 72.2 2.9 1.0 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_C PF14656.6 KFM80973.1 - 1e-40 139.6 1.1 1.1e-40 139.5 1.1 1.0 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.6 KFM80974.1 - 5.6e-140 467.3 0.0 1.1e-139 466.3 0.0 1.5 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus VWC PF00093.18 KFM80976.1 - 9.2e-30 102.7 78.3 8e-11 42.1 16.1 4.3 4 0 0 4 4 4 4 von Willebrand factor type C domain CHRD PF07452.12 KFM80976.1 - 6.7e-14 52.8 0.0 3.9e-05 24.6 0.0 4.3 4 0 0 4 4 4 2 CHRD domain Amnionless PF14828.6 KFM80976.1 - 0.0014 17.6 12.1 0.0014 17.6 12.1 4.2 4 0 0 4 4 4 2 Amnionless TILa PF12714.7 KFM80976.1 - 0.047 13.6 41.8 0.2 11.6 6.8 4.3 3 1 0 3 3 3 0 TILa domain RPS31 PF17067.5 KFM80977.1 - 0.03 14.5 0.3 0.03 14.5 0.3 1.1 1 0 0 1 1 1 0 Ribosomal protein S31e Herpes_UL52 PF03121.15 KFM80977.1 - 0.05 13.6 0.0 0.05 13.6 0.0 1.0 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Glycos_transf_1 PF00534.20 KFM80978.1 - 8.3e-33 113.3 0.0 1.2e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFM80978.1 - 6e-20 71.9 0.0 8.7e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KFM80978.1 - 2.4e-17 63.6 0.0 3.9e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFM80978.1 - 6.3e-09 36.5 0.0 9.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KFM80978.1 - 2.5e-05 24.6 0.0 5.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Tox-GHH PF15636.6 KFM80979.1 - 0.44 10.6 2.0 2 8.4 1.1 2.2 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin CBFD_NFYB_HMF PF00808.23 KFM80980.1 - 3.3e-09 36.9 0.1 7.1e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM80980.1 - 0.0002 21.7 0.4 0.00099 19.5 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 LRR_4 PF12799.7 KFM80981.1 - 1.7e-13 50.5 22.7 1.2e-05 25.5 5.1 4.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM80981.1 - 1.2e-11 44.2 23.1 1.3e-07 31.3 9.5 3.9 2 1 1 4 4 4 3 Leucine rich repeat zf-C3HC4_3 PF13920.6 KFM80981.1 - 6.4e-11 41.9 17.3 1.4e-10 40.8 17.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM80981.1 - 0.00037 20.3 14.0 0.00085 19.1 14.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 GP88 PF17338.2 KFM80981.1 - 0.047 13.1 0.7 0.33 10.4 0.1 2.5 3 1 1 4 4 4 0 Gene product 88 LRR_1 PF00560.33 KFM80981.1 - 0.17 12.5 21.3 12 6.9 0.3 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat Trypsin PF00089.26 KFM80982.1 - 1.4e-08 34.8 0.1 1.6e-08 34.7 0.1 1.0 1 0 0 1 1 1 1 Trypsin FYRN PF05964.14 KFM80983.1 - 3.3e-22 78.1 0.4 5e-22 77.5 0.4 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 KFM80983.1 - 9.5e-20 70.6 0.0 1.3e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 F/Y rich C-terminus UPF0730 PF15827.5 KFM80983.1 - 0.066 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 UPF0730 unknown protein family KASH_CCD PF14662.6 KFM80984.1 - 0.075 12.9 0.3 0.098 12.5 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fungal_TACC PF12709.7 KFM80984.1 - 0.1 13.1 0.4 0.16 12.4 0.4 1.3 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Pkinase PF00069.25 KFM80985.1 - 5e-10 39.2 0.1 5.5e-10 39.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM80985.1 - 7.5e-05 22.1 0.0 7.6e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM80985.1 - 0.039 12.9 0.0 0.039 12.9 0.0 1.0 1 0 0 1 1 1 0 Haspin like kinase domain HSP20 PF00011.21 KFM80987.1 - 1.1e-14 54.4 0.2 2e-14 53.5 0.2 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFM80987.1 - 0.0042 16.6 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA MRPL52 PF18699.1 KFM80988.1 - 4.8e-31 106.8 0.2 6.2e-31 106.4 0.2 1.2 1 0 0 1 1 1 1 Mitoribosomal protein mL52 DUF919 PF06034.11 KFM80988.1 - 0.039 13.8 5.0 0.039 13.8 5.0 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) RNA_pol_Rpb1_5 PF04998.17 KFM80989.1 - 5.2e-103 344.1 0.1 8.5e-103 343.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFM80989.1 - 5.7e-76 254.4 0.0 1.1e-75 253.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KFM80989.1 - 1.9e-64 217.0 0.0 4.1e-64 215.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KFM80989.1 - 3e-57 192.4 4.6 5.6e-57 191.5 4.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KFM80989.1 - 3.3e-51 173.3 0.0 1.1e-50 171.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KFM80989.1 - 4.7e-45 154.3 0.2 7.7e-45 153.6 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KFM80989.1 - 9.8e-39 131.6 0.1 2.6e-38 130.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KFM80989.1 - 5.7e-14 51.6 563.1 0.029 14.7 9.6 28.5 20 4 4 29 29 29 24 RNA polymerase Rpb1 C-terminal repeat AcetDehyd-dimer PF09290.11 KFM80989.1 - 0.099 12.8 0.3 0.61 10.3 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation MRG PF05712.13 KFM80990.1 - 2e-51 174.1 9.1 2e-51 174.1 9.1 1.6 2 1 0 2 2 2 1 MRG Tudor-knot PF11717.8 KFM80990.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain ExoD PF06055.12 KFM80990.1 - 0.14 11.6 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD CwfJ_C_1 PF04677.15 KFM80991.1 - 4.3e-28 97.6 1.0 7.7e-28 96.8 1.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KFM80991.1 - 2.2e-26 92.6 0.3 2.2e-26 92.6 0.3 3.9 4 0 0 4 4 4 1 Protein similar to CwfJ C-terminus 2 TMEM154 PF15102.6 KFM80991.1 - 1.5 8.7 6.5 8.3 6.3 6.5 2.3 1 0 0 1 1 1 0 TMEM154 protein family Dimer_Tnp_hAT PF05699.14 KFM80992.1 - 0.00027 20.7 0.2 0.00043 20.0 0.2 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Mito_fiss_reg PF05308.11 KFM80994.1 - 0.21 11.6 7.6 0.24 11.5 7.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Leptin PF02024.15 KFM80995.1 - 0.0066 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Leptin VIT1 PF01988.19 KFM80996.1 - 0.33 10.8 2.0 0.47 10.3 1.8 1.4 1 1 0 1 1 1 0 VIT family DAO PF01266.24 KFM80997.1 - 9.7e-45 153.7 0.0 1.1e-44 153.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM80997.1 - 0.00022 21.4 1.1 0.00053 20.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFM80997.1 - 0.0028 17.0 0.1 0.015 14.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM80997.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KFM80997.1 - 0.014 16.0 1.8 0.15 12.6 0.0 3.1 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFM80997.1 - 0.031 13.9 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KFM80997.1 - 0.079 11.6 0.0 0.28 9.8 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KFM80997.1 - 0.21 10.6 0.1 0.51 9.4 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFM80997.1 - 0.24 10.4 0.0 0.53 9.3 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Pribosyltran PF00156.27 KFM81000.1 - 1.2e-14 54.1 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFM81000.1 - 0.00077 19.0 0.0 0.00096 18.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase GLE1 PF07817.13 KFM81001.1 - 2.7e-78 262.7 0.0 2.7e-78 262.7 0.0 2.6 2 1 0 2 2 2 1 GLE1-like protein Nsp1_C PF05064.13 KFM81001.1 - 9e-05 22.3 7.3 9e-05 22.3 7.3 2.5 2 0 0 2 2 2 1 Nsp1-like C-terminal region Tox-REase-7 PF15649.6 KFM81001.1 - 0.016 15.5 0.5 0.016 15.5 0.5 2.8 3 2 1 4 4 4 0 Restriction endonuclease fold toxin 7 MukB PF04310.12 KFM81001.1 - 2.1 8.1 10.0 0.11 12.2 1.2 2.7 1 1 2 3 3 3 0 MukB N-terminal CENP-B_N PF04218.13 KFM81002.1 - 2.5e-07 30.2 0.1 3.4e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 KFM81002.1 - 0.0052 16.9 0.0 0.011 15.9 0.0 1.6 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 KFM81002.1 - 0.0063 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_1 PF01527.20 KFM81002.1 - 0.048 14.0 0.1 0.068 13.5 0.1 1.2 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.6 KFM81002.1 - 0.09 12.6 0.7 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 KFM81002.1 - 0.13 12.4 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase RRM_1 PF00076.22 KFM81003.1 - 4.2e-06 26.5 0.0 4.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFM81003.1 - 0.00067 19.6 0.0 0.00067 19.6 0.0 1.1 1 0 0 1 1 1 1 RNA binding domain RRM_7 PF16367.5 KFM81003.1 - 0.002 18.2 0.0 0.0024 17.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif Spo7_2_N PF15407.6 KFM81003.1 - 0.15 11.7 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Sporulation protein family 7 Pyr_redox_2 PF07992.14 KFM81005.1 - 3.7e-10 39.5 0.3 2e-07 30.5 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM81005.1 - 0.00036 20.7 0.0 0.00078 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KFM81005.1 - 0.00072 19.6 0.0 0.2 11.7 0.0 3.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KFM81005.1 - 0.003 16.8 0.3 2.9 7.1 0.0 2.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM81005.1 - 0.0064 15.8 0.0 0.34 10.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KFM81005.1 - 0.0069 16.8 0.1 5.1 7.6 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KFM81005.1 - 0.018 15.0 0.1 0.16 11.9 0.0 2.5 3 1 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KFM81005.1 - 0.053 12.2 0.0 0.18 10.4 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein SAM_1 PF00536.30 KFM81006.1 - 7.8e-34 115.9 0.1 6.6e-18 64.9 0.2 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM81006.1 - 5.3e-26 90.5 0.1 1.2e-11 44.5 0.3 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Caskin-tail PF16632.5 KFM81006.1 - 5.6e-08 33.1 1.1 2e-07 31.3 1.1 2.0 1 0 0 1 1 1 1 C-terminal region of Caskin DUF1741 PF08427.10 KFM81008.1 - 1.4e-62 211.4 0.6 3.4e-62 210.2 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DUF2487 PF10673.9 KFM81008.1 - 0.09 12.8 0.1 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) VHP PF02209.19 KFM81009.1 - 1.6e-18 66.5 1.6 2.6e-18 65.8 1.6 1.3 1 0 0 1 1 1 1 Villin headpiece domain Gelsolin PF00626.22 KFM81011.1 - 3e-09 36.6 0.0 0.0011 18.9 0.0 2.8 2 0 0 2 2 2 2 Gelsolin repeat Gelsolin PF00626.22 KFM81012.1 - 1.1e-05 25.2 0.0 4.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat SKA2 PF16740.5 KFM81012.1 - 0.22 11.3 2.9 0.18 11.6 0.4 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 UPAR_LY6_2 PF16975.5 KFM81014.1 - 0.0025 18.0 14.8 0.0039 17.3 14.8 1.2 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Ribosomal_S2 PF00318.20 KFM81016.1 - 3.9e-35 121.1 0.0 8.1e-17 61.2 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Atg8 PF02991.16 KFM81017.1 - 2.1e-38 130.7 0.2 2.6e-38 130.4 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFM81017.1 - 4.5e-05 23.8 0.2 0.00013 22.3 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like autophagy protein Apg12 Med29 PF11568.8 KFM81018.1 - 2.2e-40 138.1 0.0 2.6e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 29 DUF3158 PF11358.8 KFM81018.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3158) DM4_12 PF07841.13 KFM81019.1 - 6.9e-11 42.7 0.2 2.4e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 DM4/DM12 family Mid1 PF12929.7 KFM81019.1 - 0.054 12.7 0.1 0.079 12.1 0.1 1.2 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component BTB PF00651.31 KFM81020.1 - 8.2e-23 80.8 0.0 1.7e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFM81020.1 - 2.4e-06 27.6 0.5 9.3e-05 22.5 0.0 2.7 2 1 0 2 2 2 1 BTB And C-terminal Kelch MFS_1 PF07690.16 KFM81022.1 - 1.8e-20 73.2 22.2 1.8e-20 73.2 22.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFM81023.1 - 0.016 14.2 0.1 0.02 13.8 0.1 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily FliG_M PF14841.6 KFM81024.1 - 0.064 13.5 0.0 0.068 13.4 0.0 1.0 1 0 0 1 1 1 0 FliG middle domain RNase_H PF00075.24 KFM81025.1 - 6.5e-16 58.8 0.4 1.6e-15 57.5 0.1 1.9 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 KFM81025.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like zf-RVT PF13966.6 KFM81025.1 - 0.017 15.8 0.7 0.035 14.8 0.2 1.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DDE_Tnp_1_7 PF13843.6 KFM81026.1 - 6.4e-08 32.3 0.0 6.8e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 FKBP_C PF00254.28 KFM81028.1 - 0.0044 17.3 0.0 0.0053 17.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F-box-like PF12937.7 KFM81029.1 - 1.5e-13 50.4 1.4 2.6e-13 49.6 1.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM81029.1 - 1.7e-08 34.2 0.4 3.4e-08 33.2 0.4 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 KFM81030.1 - 4.6e-39 131.7 26.5 1.9e-07 31.7 0.4 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KFM81030.1 - 4.5e-15 55.3 12.5 0.0011 17.7 0.1 6.0 1 1 5 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFM81030.1 - 2.6e-12 46.9 5.7 0.085 13.2 0.0 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KFM81030.1 - 1.1e-05 25.2 2.2 1.5e-05 24.7 0.8 1.9 1 1 1 2 2 2 1 PQQ-like domain Hira PF07569.11 KFM81030.1 - 0.00018 21.3 5.7 5.2 6.7 0.1 5.1 1 1 5 6 6 6 2 TUP1-like enhancer of split DUF5046 PF16465.5 KFM81030.1 - 0.00018 21.1 1.2 1.9 7.9 0.2 3.8 1 1 2 4 4 4 2 Domain of unknown function (DUF5046) Ge1_WD40 PF16529.5 KFM81030.1 - 0.00029 19.9 5.9 1.2 8.0 0.1 4.6 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CDtoxinA PF03498.14 KFM81030.1 - 0.00038 20.1 1.1 0.93 9.1 0.1 2.9 2 1 0 2 2 2 2 Cytolethal distending toxin A/C domain AsnC_trans_reg PF01037.21 KFM81030.1 - 0.00058 19.8 0.5 0.61 10.1 0.0 4.3 5 0 0 5 5 5 1 Lrp/AsnC ligand binding domain PQQ PF01011.21 KFM81030.1 - 0.00069 19.4 0.5 37 4.5 0.0 5.2 5 0 0 5 5 5 0 PQQ enzyme repeat PALB2_WD40 PF16756.5 KFM81030.1 - 0.0073 15.3 8.2 2 7.2 0.4 4.6 1 1 4 5 5 5 2 Partner and localizer of BRCA2 WD40 domain DUF4485 PF14846.6 KFM81031.1 - 0.11 12.5 0.4 0.32 11.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) HMG_box PF00505.19 KFM81033.1 - 1.9e-23 82.6 2.0 1.9e-23 82.6 2.0 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM81033.1 - 6.9e-10 39.4 0.5 2e-09 37.9 0.5 1.8 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KFM81034.1 - 1.2e-24 86.5 2.7 3.2e-24 85.1 2.7 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM81034.1 - 9.4e-10 39.0 0.9 2.2e-09 37.7 0.9 1.7 1 0 0 1 1 1 1 HMG-box domain Histone_H2A_C PF16211.5 KFM81036.1 - 2.3e-20 72.0 1.0 4.5e-20 71.1 1.0 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM81036.1 - 1.6e-14 54.4 0.0 2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM81036.1 - 1.4e-05 25.3 0.0 1.8e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UPF0220 PF05255.11 KFM81037.1 - 2.8e-44 150.6 1.7 3.1e-44 150.4 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) zf-LITAF-like PF10601.9 KFM81037.1 - 0.05 13.9 1.1 0.68 10.2 0.0 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF485 PF04341.12 KFM81037.1 - 0.19 11.7 3.4 0.43 10.6 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF485 PDR_CDR PF06422.12 KFM81037.1 - 4.1 7.4 6.2 0.41 10.6 0.5 2.2 1 1 1 2 2 2 0 CDR ABC transporter RNA_pol_Rpb8 PF03870.15 KFM81038.1 - 1.2e-43 148.6 0.0 1.3e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KFM81038.1 - 0.0015 18.6 0.0 0.49 10.5 0.0 2.1 1 1 1 2 2 2 2 DNA-directed RNA polymerase, subunit G Yippee-Mis18 PF03226.14 KFM81039.1 - 8.8e-12 45.2 0.4 1e-11 45.0 0.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 KFM81039.1 - 0.0048 17.0 0.1 0.0062 16.6 0.1 1.1 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.8 KFM81039.1 - 0.03 14.6 0.1 0.041 14.1 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I Endonuclease_7 PF02945.15 KFM81039.1 - 0.089 12.7 2.3 4.6 7.2 2.3 2.1 1 1 0 1 1 1 0 Recombination endonuclease VII Jas PF16135.5 KFM81039.1 - 0.64 10.2 4.2 0.2 11.8 0.5 2.0 1 1 1 2 2 2 0 TPL-binding domain in jasmonate signalling SMN PF06003.12 KFM81040.1 - 8e-12 45.0 2.1 1.1e-11 44.5 2.1 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KFM81040.1 - 2.2e-08 34.2 0.1 8.9e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 Tudor domain DUF4537 PF15057.6 KFM81040.1 - 0.0012 18.8 0.0 0.0044 17.0 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) FAM199X PF15814.5 KFM81040.1 - 2.3 7.2 6.3 3.6 6.6 6.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X F5_F8_type_C PF00754.25 KFM81041.1 - 2.9e-08 33.9 0.0 4.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain DUF4025 PF13217.6 KFM81042.1 - 0.045 13.6 0.1 0.3 11.0 0.1 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4025) Carn_acyltransf PF00755.20 KFM81044.1 - 1.4e-169 565.5 0.0 1.6e-169 565.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF5519 PF17648.1 KFM81044.1 - 0.061 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5519) SH3BP5 PF05276.14 KFM81046.1 - 1.4e-77 260.6 21.0 1.9e-77 260.2 21.0 1.1 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) COG2 PF06148.11 KFM81046.1 - 0.024 14.7 9.1 0.28 11.3 5.9 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Aida_N PF08910.10 KFM81046.1 - 0.055 13.9 1.7 0.19 12.1 1.7 1.9 1 0 0 1 1 1 0 Aida N-terminus Spike_torovirin PF17072.5 KFM81046.1 - 0.056 10.6 0.3 0.084 10.0 0.3 1.2 1 0 0 1 1 1 0 Torovirinae spike glycoprotein LETM1 PF07766.13 KFM81046.1 - 0.17 11.2 8.4 0.28 10.5 8.4 1.3 1 0 0 1 1 1 0 LETM1-like protein HMMR_N PF15905.5 KFM81046.1 - 0.23 10.9 26.4 0.58 9.6 0.3 2.4 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal GRDP-like PF07173.12 KFM81046.1 - 6.2 7.5 9.8 7.9 7.1 6.2 2.4 1 1 1 2 2 2 0 Glycine-rich domain-containing protein-like PTPlike_phytase PF14566.6 KFM81046.1 - 8.3 6.5 8.4 1.8 8.7 2.7 2.3 1 1 1 3 3 3 0 Inositol hexakisphosphate TSP_NTD PF17804.1 KFM81046.1 - 9.7 6.4 15.5 22 5.2 14.8 2.0 1 1 0 1 1 1 0 Tail specific protease N-terminal domain La PF05383.17 KFM81047.1 - 4.5e-22 77.9 0.4 9.2e-22 76.9 0.4 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFM81047.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DENN PF02141.21 KFM81049.1 - 1.8e-57 194.3 0.9 3.1e-57 193.5 0.1 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain SBF2 PF12335.8 KFM81049.1 - 7.6e-39 133.7 0.2 1.3e-38 132.9 0.2 1.4 1 0 0 1 1 1 1 Myotubularin protein uDENN PF03456.18 KFM81049.1 - 4.4e-19 69.0 0.2 1.4e-18 67.4 0.2 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFM81049.1 - 7.4e-06 25.9 0.3 1.9e-05 24.5 0.3 1.8 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 KFM81049.1 - 0.0024 17.8 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Myotub-related PF06602.14 KFM81050.1 - 1e-92 310.8 0.0 8.7e-92 307.7 0.0 2.2 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain SBF2 PF12335.8 KFM81050.1 - 6.3e-58 196.1 0.3 1.5e-57 194.9 0.3 1.7 1 0 0 1 1 1 1 Myotubularin protein GRAM PF02893.20 KFM81050.1 - 9.2e-18 64.2 0.0 2.2e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 GRAM domain C1_1 PF00130.22 KFM81050.1 - 2e-14 53.2 7.9 5.9e-14 51.7 7.9 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFM81050.1 - 6.2e-14 52.4 0.0 1.4e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM81050.1 - 1e-05 25.9 2.0 8.7e-05 22.9 0.1 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFM81050.1 - 0.0048 17.1 0.1 0.013 15.8 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KFM81050.1 - 0.01 16.2 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Miga PF10265.9 KFM81051.1 - 2.7e-05 23.3 0.0 2.9e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Mitoguardin MHYT PF03707.16 KFM81051.1 - 0.069 13.3 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat TMEM89 PF15098.6 KFM81051.1 - 0.11 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 TMEM89 protein family IGFBP PF00219.18 KFM81052.1 - 4.1e-07 30.5 20.3 5.4e-07 30.1 20.3 1.2 1 0 0 1 1 1 1 Insulin-like growth factor binding protein YgbA_NO PF11756.8 KFM81052.1 - 4.2 7.8 8.4 3.3 8.1 7.4 1.4 1 1 0 1 1 1 0 Nitrous oxide-stimulated promoter LRR_8 PF13855.6 KFM81053.1 - 3.8e-45 151.5 18.0 8.1e-14 51.1 0.7 6.3 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFM81053.1 - 2.2e-22 78.7 20.9 4.7e-07 30.0 0.3 6.7 3 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM81053.1 - 3.4e-16 59.4 0.0 3.7e-07 30.2 0.0 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM81053.1 - 4.5e-08 32.6 16.7 0.45 11.2 0.0 9.1 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_9 PF14580.6 KFM81053.1 - 1.1e-05 25.0 12.3 0.0012 18.3 1.8 3.5 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KFM81053.1 - 1.8e-05 24.4 16.3 1.7 8.9 0.1 7.3 7 0 0 7 7 7 3 Leucine Rich repeat LRRCT PF01463.24 KFM81053.1 - 0.032 14.8 0.0 0.12 13.0 0.0 2.1 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain DUF4609 PF15382.6 KFM81053.1 - 0.09 12.7 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) LRR_8 PF13855.6 KFM81054.1 - 6.1e-44 147.6 28.5 1.8e-17 62.8 4.7 6.2 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFM81054.1 - 2.6e-20 72.2 35.3 5e-07 29.9 1.1 7.2 3 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM81054.1 - 1.3e-16 60.7 0.1 4.2e-09 36.4 0.0 2.8 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM81054.1 - 4.1e-12 46.0 10.5 1.8e-08 34.1 1.3 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFM81054.1 - 1.3e-07 31.2 31.8 2.9 8.8 0.1 10.5 11 1 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.6 KFM81054.1 - 1e-05 25.2 26.6 1.8 8.8 0.1 9.6 12 0 0 12 12 12 3 Leucine Rich repeat Homeodomain PF00046.29 KFM81055.1 - 7.4e-25 86.6 4.5 1.1e-24 86.1 4.5 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM81055.1 - 3.9e-05 23.4 0.1 0.0001 22.1 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain DnaJ PF00226.31 KFM81057.1 - 3.1e-27 94.5 3.2 4.7e-27 93.9 3.2 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4666 PF15697.5 KFM81058.1 - 0.087 13.5 0.6 0.15 12.8 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) DUF3915 PF13054.6 KFM81058.1 - 3.8 7.5 8.7 0.19 11.7 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) DUF3752 PF12572.8 KFM81059.1 - 2.9e-13 50.6 15.3 4.7e-13 49.9 15.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) SLC12 PF03522.15 KFM81059.1 - 3.8 6.4 14.5 6.2 5.7 14.5 1.3 1 0 0 1 1 1 0 Solute carrier family 12 zf-C2H2_4 PF13894.6 KFM81060.1 - 8.5e-05 23.1 24.4 0.087 13.7 1.6 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM81060.1 - 0.00015 22.0 9.3 0.001 19.4 1.6 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFM81060.1 - 0.026 14.1 0.1 0.026 14.1 0.1 4.2 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 KFM81060.1 - 0.034 14.6 11.5 0.74 10.4 2.1 4.1 3 0 0 3 3 3 0 Zinc-finger double domain DUF573 PF04504.14 KFM81060.1 - 0.12 13.1 4.0 12 6.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF573 zf-C2H2_jaz PF12171.8 KFM81060.1 - 0.25 11.7 9.4 0.098 13.0 0.9 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding NIPSNAP PF07978.13 KFM81061.1 - 3.2e-26 91.5 0.3 3.6e-26 91.3 0.3 1.0 1 0 0 1 1 1 1 NIPSNAP SET PF00856.28 KFM81063.1 - 4.7e-09 36.9 0.0 8.1e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFM81063.1 - 1e-07 31.9 15.7 1e-07 31.9 15.7 1.9 2 0 0 2 2 2 1 MYND finger DUF3055 PF11256.8 KFM81063.1 - 0.0056 16.9 0.1 9.5 6.6 0.0 3.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3055) BTB PF00651.31 KFM81064.1 - 7.9e-20 71.1 3.9 8.7e-20 71.0 2.1 2.1 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFM81064.1 - 6.4e-06 26.2 0.5 9.6e-05 22.4 0.1 2.5 1 1 1 2 2 2 1 BTB And C-terminal Kelch FN3_7 PF18447.1 KFM81064.1 - 0.017 15.4 1.2 0.051 13.9 1.2 1.8 1 0 0 1 1 1 0 Fibronectin type III domain CHZ PF09649.10 KFM81064.1 - 0.087 12.3 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 Histone chaperone domain CHZ TRAM1 PF08390.11 KFM81065.1 - 6.4e-18 64.2 0.2 1.6e-17 62.9 0.2 1.7 1 0 0 1 1 1 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.16 KFM81065.1 - 3.1e-08 33.6 2.2 3.1e-08 33.6 2.2 2.1 2 0 0 2 2 2 1 TLC domain LZ3wCH PF18517.1 KFM81068.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.5 3 0 0 3 3 3 0 Leucine zipper with capping helix domain AAA_lid_3 PF17862.1 KFM81069.1 - 2e-11 43.5 0.1 3.5e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KFM81069.1 - 6.3e-05 23.4 0.0 0.0011 19.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Amnionless PF14828.6 KFM81070.1 - 1.5e-72 244.9 0.0 1.6e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Amnionless VWC PF00093.18 KFM81070.1 - 0.052 13.9 8.9 0.12 12.7 8.9 1.6 1 0 0 1 1 1 0 von Willebrand factor type C domain DUF4296 PF14129.6 KFM81071.1 - 0.0063 17.1 0.6 0.0087 16.6 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4296) MSA-2c PF12238.8 KFM81071.1 - 0.0095 16.0 1.6 0.011 15.8 1.6 1.0 1 0 0 1 1 1 1 Merozoite surface antigen 2c OmpH PF03938.14 KFM81071.1 - 0.22 11.9 4.5 0.31 11.4 4.4 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Saf_2TM PF18303.1 KFM81073.1 - 0.023 14.3 0.1 0.026 14.1 0.1 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF2368 PF10166.9 KFM81074.1 - 1e-21 76.9 0.0 1.2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) Kelch_1 PF01344.25 KFM81075.1 - 1.8e-83 273.9 11.6 5e-18 64.4 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFM81075.1 - 3.3e-48 160.5 0.8 2.7e-09 37.0 0.0 6.4 3 1 3 6 6 6 6 Kelch motif BACK PF07707.15 KFM81075.1 - 2.3e-34 117.6 1.3 2.7e-34 117.4 0.2 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFM81075.1 - 1.1e-33 113.9 1.8 8.7e-07 28.7 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFM81075.1 - 2.4e-31 107.4 6.4 7.6e-07 29.3 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KFM81075.1 - 1.3e-29 102.7 1.0 2.3e-29 101.8 1.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 KFM81075.1 - 1.2e-19 70.1 7.6 0.00023 21.1 0.0 6.5 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM81075.1 - 1.7e-08 34.3 9.2 0.013 15.5 0.0 5.7 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.8 KFM81075.1 - 0.013 15.7 2.4 2.3 8.5 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) HU-CCDC81_euk_1 PF14908.6 KFM81075.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 DUF287 PF03384.14 KFM81075.1 - 0.19 12.1 0.2 0.51 10.8 0.1 1.8 2 0 0 2 2 1 0 Drosophila protein of unknown function, DUF287 DUF2458 PF10454.9 KFM81076.1 - 0.067 12.8 4.9 0.065 12.9 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) PAS_6 PF08348.11 KFM81076.1 - 2.1 8.2 5.1 0.65 9.9 0.1 2.5 3 0 0 3 3 3 0 YheO-like PAS domain SSDP PF04503.13 KFM81077.1 - 1.5e-77 261.7 87.3 1.8e-77 261.4 87.3 1.0 1 0 0 1 1 1 1 Single-stranded DNA binding protein, SSDP CUB PF00431.20 KFM81079.1 - 2e-56 189.1 0.3 6.9e-18 65.0 0.1 4.2 4 0 0 4 4 4 4 CUB domain Ldl_recept_a PF00057.18 KFM81079.1 - 0.00014 22.0 13.5 0.00035 20.7 13.5 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A AIM3 PF17096.5 KFM81079.1 - 0.0069 17.3 0.1 0.014 16.3 0.1 1.5 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 3 Aldolase_II PF00596.21 KFM81080.1 - 4.4e-38 131.1 0.1 5.6e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.16 KFM81081.1 - 8.8e-05 21.6 5.8 0.00011 21.3 5.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM81081.1 - 0.048 12.5 5.1 0.081 11.8 5.1 1.4 1 1 0 1 1 1 0 Sugar (and other) transporter Sugar_tr PF00083.24 KFM81082.1 - 8.9e-10 38.0 1.6 1.2e-09 37.6 1.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM81082.1 - 1.1e-08 34.4 5.7 1.1e-08 34.4 5.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFM81082.1 - 0.037 12.5 1.3 0.056 11.9 1.3 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Cornifin PF02389.15 KFM81083.1 - 0.15 12.3 0.2 0.3 11.3 0.2 1.5 1 0 0 1 1 1 0 Cornifin (SPRR) family Chorion_3 PF05387.11 KFM81084.1 - 0.078 12.6 0.4 0.084 12.5 0.4 1.2 1 0 0 1 1 1 0 Chorion family 3 TROVE PF05731.11 KFM81085.1 - 1.5e-80 271.4 9.4 2.5e-51 175.1 2.4 2.5 1 1 1 2 2 2 2 TROVE domain DUF4062 PF13271.6 KFM81085.1 - 4.8e-20 71.7 0.2 4.7e-18 65.3 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4062) WD40 PF00400.32 KFM81085.1 - 2.9e-17 62.7 28.2 5.9e-05 23.8 1.5 8.4 9 0 0 9 9 9 5 WD domain, G-beta repeat NACHT PF05729.12 KFM81085.1 - 1.4e-07 31.6 0.1 5.2e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KFM81085.1 - 2.3e-07 31.2 0.0 9.5e-07 29.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain ANAPC4_WD40 PF12894.7 KFM81085.1 - 4.8e-07 30.0 1.8 2.9 8.2 0.0 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KFM81085.1 - 0.00049 20.5 0.3 0.0058 17.0 0.3 2.5 1 1 0 1 1 1 1 AAA ATPase domain APAF1_C PF17908.1 KFM81085.1 - 0.0012 18.9 1.9 0.0017 18.4 0.1 2.2 2 0 0 2 2 2 1 APAF-1 helical domain AAA_7 PF12775.7 KFM81085.1 - 0.025 14.1 0.0 0.065 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KFM81085.1 - 0.062 13.7 0.0 1.1 9.7 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KFM81085.1 - 0.084 11.9 0.0 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein WD40 PF00400.32 KFM81086.1 - 5.7e-11 42.8 14.2 9.2e-06 26.3 0.5 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_like PF17005.5 KFM81086.1 - 1.4e-08 34.5 1.1 5.7e-06 25.9 0.7 3.4 2 1 0 2 2 2 2 WD40-like domain DUF5050 PF16472.5 KFM81086.1 - 0.013 14.8 0.3 0.3 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) 5_nucleotid PF05761.14 KFM81086.1 - 0.079 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family Far-17a_AIG1 PF04750.14 KFM81087.1 - 1.2e-48 165.1 21.4 1.4e-48 164.9 21.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein KH_9 PF17904.1 KFM81089.1 - 3.6e-33 113.8 3.0 1.7e-32 111.6 1.5 2.5 2 0 0 2 2 2 1 FMRP KH0 domain Tudor_FRX1 PF18336.1 KFM81089.1 - 1.2e-23 82.8 0.5 2.6e-23 81.7 0.1 1.9 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain KH_1 PF00013.29 KFM81089.1 - 2.7e-19 68.8 1.6 1.9e-10 40.4 0.3 2.8 3 0 0 3 3 3 2 KH domain FXMRP1_C_core PF12235.8 KFM81089.1 - 9.2e-14 52.3 3.7 2.3e-13 51.0 3.7 1.7 1 0 0 1 1 1 1 Fragile X-related 1 protein core C terminal Agenet PF05641.12 KFM81089.1 - 5.6e-11 42.8 5.2 1.1e-06 29.0 0.7 3.7 3 1 0 3 3 3 2 Agenet domain KH_4 PF13083.6 KFM81089.1 - 0.0072 16.2 1.8 0.84 9.6 0.4 3.1 2 1 1 3 3 3 1 KH domain KH_2 PF07650.17 KFM81089.1 - 0.026 14.3 1.1 2.6 7.9 0.0 3.1 3 0 0 3 3 3 0 KH domain SH3_1 PF00018.28 KFM81089.1 - 0.036 13.7 0.3 0.092 12.4 0.3 1.6 1 0 0 1 1 1 0 SH3 domain Glyco_hydro_15 PF00723.21 KFM81090.1 - 2.3e-97 326.6 0.0 2.8e-97 326.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 I-set PF07679.16 KFM81092.1 - 5.2e-48 161.1 0.0 1.9e-17 63.1 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM81092.1 - 3.3e-45 152.6 0.0 8.1e-14 52.0 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFM81092.1 - 5.6e-28 97.0 0.0 1.7e-09 37.7 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFM81092.1 - 5.2e-27 94.0 0.0 6.2e-09 36.1 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFM81092.1 - 4.7e-19 68.6 0.0 0.00033 20.8 0.0 6.1 4 2 1 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM81092.1 - 3e-10 40.0 0.0 0.028 14.5 0.0 3.4 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM81092.1 - 3.5e-08 32.9 0.0 0.0036 16.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 KFM81092.1 - 8.9e-05 22.7 0.0 1.9 8.8 0.0 3.4 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM81092.1 - 0.00027 20.9 0.1 0.48 10.5 0.0 3.7 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain DUF1918 PF08940.11 KFM81092.1 - 0.0011 18.5 0.6 1.9 8.1 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1918) Ig_C17orf99 PF17736.1 KFM81092.1 - 0.0048 16.9 0.0 13 5.9 0.0 3.4 4 0 0 4 4 3 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFM81092.1 - 0.0052 17.0 0.0 5.4 7.3 0.0 3.2 1 1 2 3 3 3 1 Natural killer cell receptor 2B4 rOmpB PF12334.8 KFM81092.1 - 0.04 13.4 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Rickettsia outer membrane protein B C2-set PF05790.15 KFM81092.1 - 0.14 12.3 0.0 3.1 8.1 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain fn3 PF00041.21 KFM81093.1 - 7.7e-14 51.8 0.4 1.4e-05 25.3 0.1 2.1 2 0 0 2 2 2 2 Fibronectin type III domain M_domain PF12938.7 KFM81097.1 - 3e-20 73.1 75.8 3e-20 73.1 75.8 5.8 5 2 1 6 6 6 1 M domain of GW182 RRM_1 PF00076.22 KFM81097.1 - 5.9e-07 29.2 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA PF00627.31 KFM81097.1 - 0.0011 18.8 0.8 0.0026 17.6 0.8 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RRM_occluded PF16842.5 KFM81097.1 - 0.039 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nas2_N PF18265.1 KFM81097.1 - 0.21 11.6 0.8 1 9.3 0.1 2.3 2 0 0 2 2 2 0 Nas2 N_terminal domain PHD PF00628.29 KFM81099.1 - 1.1e-16 60.5 29.7 9.5e-09 35.0 12.5 3.4 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.6 KFM81099.1 - 0.00013 21.4 2.1 0.00013 21.4 2.1 4.3 4 1 0 4 4 4 1 PHD-finger PHD_4 PF16866.5 KFM81099.1 - 0.00062 19.8 10.4 0.00062 19.8 10.4 4.3 1 1 3 4 4 4 1 PHD-finger C1_1 PF00130.22 KFM81099.1 - 0.046 13.6 0.7 0.046 13.6 0.7 4.0 2 1 2 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Requiem_N PF14051.6 KFM81099.1 - 0.048 13.9 0.0 0.048 13.9 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of DPF2/REQ. PAX PF00292.18 KFM81099.1 - 0.091 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 'Paired box' domain Ribosomal_L18_c PF14204.6 KFM81099.1 - 0.15 13.0 3.9 0.45 11.5 3.9 1.8 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region ENTH PF01417.20 KFM81101.1 - 2.3e-50 169.8 0.2 4.4e-50 168.9 0.2 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFM81101.1 - 5.5e-06 25.6 0.2 8.7e-06 24.9 0.2 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KFM81101.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain UCR_UQCRX_QCR9 PF05365.12 KFM81101.1 - 0.021 14.8 0.3 0.039 13.9 0.3 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like UIM PF02809.20 KFM81101.1 - 9.9 6.3 21.4 0.055 13.4 6.5 3.2 3 0 0 3 3 3 0 Ubiquitin interaction motif NUDIX PF00293.28 KFM81102.1 - 1.5e-14 54.2 0.0 1.9e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S9 PF00380.19 KFM81103.1 - 6.6e-31 107.3 0.0 1.9e-30 105.9 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Brix PF04427.18 KFM81104.1 - 4.5e-42 144.3 0.4 4.5e-42 144.3 0.5 1.5 2 0 0 2 2 2 1 Brix domain APG5 PF04106.12 KFM81105.1 - 3.8e-54 183.7 1.1 5.2e-54 183.2 1.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 zf-C2H2 PF00096.26 KFM81106.1 - 0.026 15.0 4.1 0.026 15.0 4.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM81106.1 - 0.033 14.6 8.0 0.93 10.0 0.5 2.8 1 1 1 2 2 2 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 KFM81106.1 - 0.33 10.9 6.3 0.5 10.3 1.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFM81106.1 - 0.56 10.3 3.2 12 6.0 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFM81106.1 - 0.74 10.8 7.1 0.52 11.3 1.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KFM81106.1 - 0.84 10.1 3.9 4 8.0 0.6 3.9 2 1 0 2 2 2 0 Zinc-finger of C2H2 type DUF2897 PF11446.8 KFM81106.1 - 3 7.8 8.7 3.9 7.4 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2897) Lactamase_B_2 PF12706.7 KFM81108.1 - 2.7e-15 56.4 0.0 5.4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFM81108.1 - 5.4e-10 39.4 0.2 1.1e-09 38.4 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KFM81108.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain NUDIX PF00293.28 KFM81109.1 - 3.5e-07 30.3 0.0 6.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DNA_ligase_A_M PF01068.21 KFM81110.1 - 2e-47 161.5 0.0 1.1e-46 159.0 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFM81110.1 - 3.1e-43 148.1 1.1 4.9e-43 147.4 0.2 1.9 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 KFM81110.1 - 1.4e-21 76.7 0.5 1.9e-09 37.8 0.0 3.1 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KFM81110.1 - 1.3e-18 67.5 0.0 3.9e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 KFM81110.1 - 1.1e-14 54.5 1.8 5.9e-06 26.6 0.1 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KFM81110.1 - 5.7e-10 39.1 0.4 2.1e-09 37.4 0.4 2.1 1 0 0 1 1 1 1 DNA ligase IV RNA_ligase PF09414.10 KFM81110.1 - 1.1e-09 38.8 0.0 2.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 RNA ligase RTT107_BRCT_5 PF16770.5 KFM81110.1 - 4.6e-07 29.7 0.1 0.00089 19.1 0.0 2.8 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KFM81110.1 - 5.4e-07 29.8 2.0 0.051 13.9 0.0 3.5 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain mRNA_cap_enzyme PF01331.19 KFM81110.1 - 0.00073 19.4 0.0 0.011 15.6 0.0 2.5 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain XendoU PF09412.10 KFM81110.1 - 0.0071 15.6 1.5 0.087 12.0 0.3 2.4 2 0 0 2 2 2 1 Endoribonuclease XendoU Spaetzle PF16077.5 KFM81111.1 - 6.8e-27 93.8 0.9 1.1e-26 93.1 0.9 1.4 1 0 0 1 1 1 1 Spaetzle mTERF PF02536.14 KFM81112.1 - 1.4e-23 83.3 3.6 1.7e-17 63.3 2.7 2.7 1 1 1 2 2 2 2 mTERF Rep_N PF08724.10 KFM81112.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 2 0 0 2 2 2 0 Rep protein catalytic domain like DUF3226 PF11536.8 KFM81112.1 - 0.14 11.8 4.3 0.26 10.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3226) PPP5 PF08321.12 KFM81117.1 - 2.3e-10 40.6 0.8 1.3e-09 38.2 0.1 2.1 2 1 0 2 2 2 1 PPP5 TPR repeat region IQ PF00612.27 KFM81117.1 - 1.3e-06 27.7 1.8 5.5e-06 25.7 1.8 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Metallophos PF00149.28 KFM81118.1 - 3.1e-08 34.4 0.0 3.1e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GET2 PF08690.10 KFM81119.1 - 0.027 14.2 0.4 0.027 14.2 0.4 3.4 2 1 1 3 3 3 0 GET complex subunit GET2 DUF3498 PF12004.8 KFM81119.1 - 3.3 6.8 29.9 7.4 5.6 29.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) DnaJ PF00226.31 KFM81120.1 - 9.2e-09 35.3 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 KFM81121.1 - 1.5e-16 59.1 1.3 0.0006 19.7 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat RRM_1 PF00076.22 KFM81121.1 - 3.9e-15 55.4 0.0 6.3e-14 51.6 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_1 PF00515.28 KFM81121.1 - 2e-10 40.0 1.2 0.048 13.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM81121.1 - 1.9e-09 37.0 0.5 0.014 15.6 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM81121.1 - 2e-05 24.2 1.0 0.2 11.4 0.0 4.4 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 KFM81121.1 - 0.00014 22.5 0.0 0.0037 17.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM81121.1 - 0.00027 21.1 0.9 1.4 9.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM81121.1 - 0.00083 20.0 0.7 0.41 11.6 0.0 3.6 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM81121.1 - 0.002 18.4 0.9 0.14 12.5 0.6 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat RRM_occluded PF16842.5 KFM81121.1 - 0.0047 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif TPR_9 PF13371.6 KFM81121.1 - 0.0076 16.4 0.7 1.5 9.0 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat PHC2_SAM_assoc PF16616.5 KFM81121.1 - 0.013 16.3 9.8 0.024 15.5 9.8 1.5 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DUF4523 PF15023.6 KFM81121.1 - 0.059 13.2 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) TPR_7 PF13176.6 KFM81121.1 - 0.082 13.0 0.5 32 4.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Nop25 PF09805.9 KFM81121.1 - 0.19 12.2 13.4 0.33 11.4 13.4 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CFIA_Pcf11 PF11526.8 KFM81121.1 - 0.21 12.1 7.0 4.5 7.8 6.3 2.5 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 zf_CCCH_4 PF18345.1 KFM81121.1 - 0.31 11.2 5.3 0.76 9.9 5.3 1.7 1 0 0 1 1 1 0 Zinc finger domain 5-FTHF_cyc-lig PF01812.20 KFM81121.1 - 0.5 10.2 4.0 0.89 9.4 4.0 1.3 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family CSRNP_N PF16019.5 KFM81121.1 - 1.1 9.1 8.5 1.9 8.4 8.5 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus BTAD PF03704.17 KFM81121.1 - 2 8.9 5.2 13 6.2 0.0 2.9 3 1 0 3 3 2 0 Bacterial transcriptional activator domain IHABP4_N PF16174.5 KFM81121.1 - 2.4 8.7 15.4 4.2 7.9 15.4 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal PNISR PF15996.5 KFM81121.1 - 3.7 7.8 15.4 6.4 7.0 15.4 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR TFIIF_alpha PF05793.12 KFM81121.1 - 4.7 5.7 21.0 0.24 10.0 15.7 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Menin PF05053.13 KFM81121.1 - 5.4 5.2 10.4 2.7 6.3 8.4 1.4 2 0 0 2 2 2 0 Menin Presenilin PF01080.17 KFM81121.1 - 9.7 4.8 7.4 12 4.6 7.4 1.1 1 0 0 1 1 1 0 Presenilin TatD_DNase PF01026.21 KFM81123.1 - 5.2e-15 55.5 0.0 5.9e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase CbeA_antitoxin PF06154.11 KFM81123.1 - 0.02 15.5 0.0 0.033 14.8 0.0 1.4 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A Sedlin_N PF04628.13 KFM81123.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region PTEN_C2 PF10409.9 KFM81126.1 - 8.2e-11 41.8 0.0 8.6e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein TTC5_OB PF16669.5 KFM81128.1 - 4.9e-34 116.5 0.4 9.4e-34 115.6 0.4 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_1 PF00515.28 KFM81128.1 - 3.6e-10 39.2 10.0 0.00022 20.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM81128.1 - 8.8e-10 37.9 9.6 0.00046 20.1 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM81128.1 - 6.4e-08 33.1 0.0 0.00042 20.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM81128.1 - 1.2e-07 32.0 0.0 0.0052 17.0 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM81128.1 - 1.3e-07 31.5 0.4 0.018 15.4 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM81128.1 - 3.4e-05 23.7 8.0 0.00081 19.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM81128.1 - 4.5e-05 23.5 0.0 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM81128.1 - 5.8e-05 23.5 0.0 0.0029 18.1 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM81128.1 - 0.00019 21.2 0.5 0.41 10.8 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM81128.1 - 0.0033 18.1 0.0 1.8 9.6 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM81128.1 - 0.006 16.2 1.4 19 5.0 0.1 4.2 3 1 1 4 4 4 0 TPR repeat TPR_6 PF13174.6 KFM81128.1 - 0.036 14.7 1.5 16 6.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SMC_ScpB PF04079.16 KFM81128.1 - 0.12 11.9 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB RNA_pol_N PF01194.17 KFM81129.1 - 1.1e-33 115.3 0.2 1.2e-33 115.1 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KFM81129.1 - 0.044 14.0 0.1 0.063 13.5 0.1 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ank_2 PF12796.7 KFM81130.1 - 2.4e-120 393.3 37.6 3.5e-15 56.4 0.0 10.9 3 3 9 13 13 13 13 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM81130.1 - 3.1e-113 368.3 35.5 8.1e-14 51.5 0.2 15.7 5 5 12 17 17 17 15 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM81130.1 - 1.5e-108 353.9 36.0 5.5e-12 46.0 0.2 15.8 6 4 10 17 17 17 16 Ankyrin repeats (many copies) Ank PF00023.30 KFM81130.1 - 4.7e-106 343.0 35.3 9e-08 32.2 0.2 18.2 18 0 0 18 18 18 15 Ankyrin repeat Ank_3 PF13606.6 KFM81130.1 - 5.6e-97 305.9 26.5 8.5e-07 28.8 0.1 19.3 19 0 0 19 19 19 14 Ankyrin repeat PARP PF00644.20 KFM81130.1 - 4.6e-28 98.2 3.7 1.9e-24 86.3 0.3 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.17 KFM81130.1 - 2.4e-13 50.0 0.3 6.7e-13 48.5 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM81130.1 - 3.1e-11 43.6 0.3 6.6e-11 42.5 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HSP70 PF00012.20 KFM81131.1 - 1.5e-270 898.6 18.1 1.8e-270 898.4 18.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM81131.1 - 1.3e-13 50.5 9.3 2.5e-13 49.5 1.0 2.8 3 1 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 KFM81131.1 - 8.7e-06 25.6 0.0 3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFM81131.1 - 0.00071 20.0 9.1 0.17 12.3 0.3 4.0 3 2 0 3 3 3 2 Cell division protein FtsA Talin_middle PF09141.10 KFM81131.1 - 0.055 13.5 2.9 0.11 12.5 0.4 2.6 3 0 0 3 3 3 0 Talin, middle domain Spectrin PF00435.21 KFM81131.1 - 1 9.8 7.6 2.5 8.6 7.6 1.6 1 0 0 1 1 1 0 Spectrin repeat TRAF_BIRC3_bd PF16673.5 KFM81131.1 - 3.3 7.6 7.6 5.8 6.8 0.7 3.7 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain HR1 PF02185.16 KFM81131.1 - 9.9 6.4 9.9 1.5 9.0 0.6 3.1 2 1 1 3 3 3 0 Hr1 repeat Acetyltransf_3 PF13302.7 KFM81132.1 - 4e-16 59.9 0.0 4.5e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM81132.1 - 3e-05 24.2 0.0 3.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CUB PF00431.20 KFM81133.1 - 3.6e-08 33.7 1.7 5.1e-05 23.6 0.3 2.1 2 0 0 2 2 2 2 CUB domain CUB PF00431.20 KFM81134.1 - 2.2e-58 195.3 7.8 1e-14 54.8 0.1 5.6 5 0 0 5 5 5 5 CUB domain ISET-FN3_linker PF16625.5 KFM81134.1 - 0.79 10.3 8.1 1.8 9.1 0.4 3.1 3 0 0 3 3 3 0 Unstructured linking region I-set and fnIII on Brother of CDO CUB PF00431.20 KFM81136.1 - 6.5e-55 184.2 0.1 5.3e-16 58.9 0.0 4.4 4 0 0 4 4 4 4 CUB domain IL4Ra_N PF09238.10 KFM81136.1 - 0.1 13.0 0.3 16 5.9 0.0 2.9 3 0 0 3 3 3 0 Interleukin-4 receptor alpha chain, N-terminal zf_C2H2_6 PF18450.1 KFM81136.1 - 2.3 8.0 5.9 1.5 8.6 0.4 3.2 3 0 0 3 3 3 0 Zinc Finger domain GDPD PF03009.17 KFM81137.1 - 4.9e-21 75.6 0.1 7.1e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 KFM81137.1 - 3.3e-14 52.5 0.1 1.4e-13 50.6 0.0 2.0 3 0 0 3 3 3 1 Starch binding domain PI-PLC-X PF00388.19 KFM81137.1 - 0.059 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain GDPD PF03009.17 KFM81138.1 - 3.5e-28 99.1 0.0 3.9e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Glyco_hydro_114 PF03537.13 KFM81138.1 - 0.0086 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Peptidase_C13 PF01650.18 KFM81139.1 - 1.7e-47 162.1 0.0 2.2e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 KFM81139.1 - 0.018 15.3 0.2 0.064 13.5 0.0 1.9 2 0 0 2 2 2 0 Mid domain of argonaute DUF4226 PF10774.9 KFM81140.1 - 0.011 16.0 1.2 0.021 15.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Pyridoxal_deC PF00282.19 KFM81141.1 - 3.8e-152 506.3 0.0 4.5e-152 506.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFM81141.1 - 0.00014 21.2 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Peroxin-3 PF04882.12 KFM81143.1 - 4.5e-23 82.0 0.2 3.6e-07 29.6 0.7 3.0 1 1 2 3 3 3 3 Peroxin-3 Glyco_transf_41 PF13844.6 KFM81144.1 - 1.5e-261 867.8 0.0 1.9e-261 867.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_11 PF13414.6 KFM81144.1 - 9.2e-94 306.9 35.4 1e-11 44.3 0.5 13.4 3 2 10 13 13 13 12 TPR repeat TPR_1 PF00515.28 KFM81144.1 - 8.8e-93 300.7 35.3 2.3e-09 36.7 0.0 13.9 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_2 PF07719.17 KFM81144.1 - 4e-71 229.5 31.7 9.4e-07 28.5 0.4 13.3 14 0 0 14 14 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 KFM81144.1 - 9e-65 210.5 40.9 5.1e-06 26.5 0.2 14.7 15 0 0 15 15 15 12 Tetratricopeptide repeat TPR_8 PF13181.6 KFM81144.1 - 1.6e-62 202.5 18.1 1.7e-05 24.7 0.1 14.0 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_12 PF13424.6 KFM81144.1 - 3.2e-44 149.1 32.8 4.4e-10 39.7 1.4 10.3 5 3 5 11 11 11 8 Tetratricopeptide repeat TPR_14 PF13428.6 KFM81144.1 - 1.7e-43 143.5 15.2 0.00015 22.3 0.0 12.5 5 3 7 12 12 12 10 Tetratricopeptide repeat TPR_16 PF13432.6 KFM81144.1 - 3.3e-41 139.7 11.5 2.2e-06 28.2 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFM81144.1 - 2.3e-39 133.7 24.5 6.6e-07 29.8 0.1 8.7 4 3 3 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 KFM81144.1 - 1.2e-33 114.0 50.8 6.1e-06 25.9 0.8 12.5 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_7 PF13176.6 KFM81144.1 - 1.2e-32 109.5 17.6 0.011 15.7 0.0 13.4 13 1 1 14 14 13 8 Tetratricopeptide repeat TPR_9 PF13371.6 KFM81144.1 - 6e-18 64.8 9.1 0.0061 16.7 0.2 6.6 4 2 3 7 7 6 6 Tetratricopeptide repeat NARP1 PF12569.8 KFM81144.1 - 4e-16 59.0 3.2 0.00014 21.0 0.1 5.8 1 1 5 6 6 6 4 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KFM81144.1 - 6.9e-13 48.3 14.5 0.32 11.7 0.0 10.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM81144.1 - 7.9e-11 41.9 10.0 0.0038 16.6 0.1 5.1 1 1 2 4 4 4 4 MalT-like TPR region TPR_4 PF07721.14 KFM81144.1 - 3.9e-10 39.4 9.8 3.5 8.5 0.0 8.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFM81144.1 - 3.8e-08 32.9 8.4 0.0054 16.0 0.1 4.7 1 1 0 3 3 3 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 KFM81144.1 - 6.9e-08 32.3 10.0 0.33 10.4 0.1 5.4 5 0 0 5 5 5 2 Est1 DNA/RNA binding domain FAT PF02259.23 KFM81144.1 - 9.6e-08 31.6 0.0 0.35 10.0 0.0 6.0 2 2 3 6 6 6 1 FAT domain TPR_21 PF09976.9 KFM81144.1 - 6.6e-06 26.0 10.4 0.35 10.6 0.1 5.3 3 2 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 KFM81144.1 - 3e-05 23.9 2.5 0.84 9.7 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KFM81144.1 - 5.1e-05 23.3 6.6 0.33 10.8 0.2 4.5 3 1 0 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal BTAD PF03704.17 KFM81144.1 - 0.00038 20.9 14.0 3.4 8.1 0.5 5.7 2 2 1 4 4 4 1 Bacterial transcriptional activator domain MIT PF04212.18 KFM81144.1 - 0.00048 20.1 21.9 5 7.3 0.1 8.6 7 1 2 9 9 8 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 KFM81144.1 - 0.0079 15.9 11.6 8.4 6.1 0.1 6.8 3 2 4 7 7 7 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 KFM81144.1 - 0.011 16.0 14.3 0.57 10.5 0.3 6.7 3 2 3 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM81144.1 - 0.016 15.2 0.1 0.17 12.0 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KFM81144.1 - 0.036 14.3 20.3 2.3 8.5 0.2 6.3 4 2 4 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 KFM81144.1 - 0.04 13.4 7.6 3.6 7.1 0.0 5.7 7 1 1 8 8 8 0 SHNi-TPR Mad3_BUB1_I PF08311.12 KFM81144.1 - 0.065 13.2 8.7 56 3.7 0.1 6.4 6 1 1 7 7 6 0 Mad3/BUB1 homology region 1 Fer4_13 PF13370.6 KFM81144.1 - 0.15 12.7 0.6 10 6.7 0.0 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I TOM20_plant PF06552.12 KFM81144.1 - 0.17 11.7 0.7 43 3.8 0.0 3.9 2 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 DUF627 PF04781.12 KFM81144.1 - 0.89 9.6 8.2 62 3.7 0.0 5.4 3 1 2 5 5 5 0 Protein of unknown function (DUF627) DUF5113 PF17140.4 KFM81144.1 - 1.3 8.9 12.1 61 3.4 0.0 5.8 4 2 2 6 6 6 0 Domain of unknown function (DUF5113) PPR PF01535.20 KFM81144.1 - 2.3 8.7 7.7 1e+02 3.5 0.1 6.4 9 0 0 9 9 5 0 PPR repeat IBR PF01485.21 KFM81145.1 - 2.1e-10 40.7 8.0 2.1e-10 40.7 8.0 1.5 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain RVT_1 PF00078.27 KFM81146.1 - 0.0084 15.6 0.0 0.0093 15.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MA3 PF02847.17 KFM81146.1 - 0.016 15.2 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 MA3 domain Helicase_C PF00271.31 KFM81147.1 - 6e-14 52.3 0.0 2.9e-13 50.1 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KFM81147.1 - 8.1e-14 51.8 0.0 1.9e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFM81147.1 - 8.7e-11 42.0 0.1 4e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFM81147.1 - 4e-08 33.2 0.3 1.2e-07 31.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RRM_1 PF00076.22 KFM81147.1 - 2.6e-06 27.1 0.1 0.48 10.3 0.1 5.1 5 0 0 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_22 PF13401.6 KFM81147.1 - 0.00047 20.5 0.0 0.0022 18.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KFM81147.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Helicase KH_1 PF00013.29 KFM81147.1 - 0.029 14.2 5.5 2.6 8.0 0.0 3.7 3 0 0 3 3 3 0 KH domain DUF4140 PF13600.6 KFM81147.1 - 0.04 14.3 0.0 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) AAA_30 PF13604.6 KFM81147.1 - 0.077 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M13_N PF05649.13 KFM81150.1 - 6.6e-63 213.7 0.0 7.8e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 PH PF00169.29 KFM81152.1 - 9.4e-07 29.3 0.1 6.3e-05 23.4 0.0 2.3 2 1 0 2 2 2 2 PH domain Proteasome PF00227.26 KFM81155.1 - 4.5e-52 176.3 0.1 5.8e-52 175.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM81155.1 - 1.7e-14 53.1 0.1 2.8e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF555 PF04475.12 KFM81155.1 - 0.05 13.9 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF555) SH3_9 PF14604.6 KFM81156.1 - 5.1e-12 45.5 0.1 6e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM81156.1 - 5.4e-06 26.0 0.0 6.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM81156.1 - 6.2e-06 25.7 0.1 1.1e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 SH3 domain AAA PF00004.29 KFM81157.1 - 2.5e-44 150.9 0.0 6.3e-44 149.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM81157.1 - 1.6e-10 40.6 0.1 4e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFM81157.1 - 4.3e-10 39.4 0.2 2.4e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KFM81157.1 - 1.9e-08 34.6 0.0 4.5e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFM81157.1 - 5e-08 33.0 0.1 1.5e-07 31.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM81157.1 - 2.6e-06 27.9 0.2 0.00088 19.7 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain DUF815 PF05673.13 KFM81157.1 - 6.3e-05 22.3 0.4 0.00031 20.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFM81157.1 - 7.9e-05 23.0 0.7 0.044 14.0 0.7 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFM81157.1 - 0.00011 22.0 0.0 0.00034 20.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KFM81157.1 - 0.00052 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 KFM81157.1 - 0.00059 19.3 0.1 0.0013 18.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFM81157.1 - 0.0007 19.6 0.1 0.0052 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFM81157.1 - 0.0011 19.3 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFM81157.1 - 0.0014 18.6 0.1 0.16 11.8 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_33 PF13671.6 KFM81157.1 - 0.0017 18.6 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM81157.1 - 0.002 18.7 0.0 0.0083 16.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KFM81157.1 - 0.0034 17.2 0.1 0.0075 16.0 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein NACHT PF05729.12 KFM81157.1 - 0.0053 16.7 0.1 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 NACHT domain TIP49 PF06068.13 KFM81157.1 - 0.007 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase_2 PF01637.18 KFM81157.1 - 0.014 15.3 0.1 0.15 12.0 0.0 2.3 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KFM81157.1 - 0.021 14.8 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KFM81157.1 - 0.024 14.5 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM81157.1 - 0.029 14.1 0.3 0.55 9.9 0.0 2.6 3 1 0 3 3 2 0 Sigma-54 interaction domain TniB PF05621.11 KFM81157.1 - 0.033 13.6 0.0 2.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KFM81157.1 - 0.036 13.6 0.1 0.26 10.8 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KFM81157.1 - 0.04 13.1 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KFM81157.1 - 0.057 13.1 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain Peptidase_S49_N PF08496.10 KFM81157.1 - 0.067 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_25 PF13481.6 KFM81157.1 - 0.068 12.7 2.5 0.11 12.0 0.1 2.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KFM81157.1 - 0.078 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 KFM81157.1 - 0.08 12.3 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.17 KFM81157.1 - 0.081 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 KFM81157.1 - 0.12 12.8 0.1 0.42 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3450 PF11932.8 KFM81157.1 - 0.13 11.6 1.0 0.25 10.6 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ABC_tran PF00005.27 KFM81157.1 - 0.14 12.7 0.1 0.37 11.3 0.0 2.0 2 1 0 2 2 1 0 ABC transporter AAA_30 PF13604.6 KFM81157.1 - 0.15 11.8 0.1 0.33 10.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain DMPK_coil PF08826.10 KFM81158.1 - 0.003 17.6 0.7 0.013 15.6 0.7 2.1 1 0 0 1 1 1 1 DMPK coiled coil domain like GIT_CC PF16559.5 KFM81158.1 - 0.059 13.2 3.2 0.14 12.0 3.2 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KFM81158.1 - 0.64 10.7 9.0 0.51 11.0 6.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF5595 PF18077.1 KFM81158.1 - 1.1 9.4 6.4 0.13 12.4 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Spc42p PF11544.8 KFM81158.1 - 1.5 8.9 9.8 0.49 10.4 5.4 2.4 1 1 2 3 3 3 0 Spindle pole body component Spc42p zf-C3HC4_2 PF13923.6 KFM81159.1 - 1.4e-08 34.4 10.7 3.7e-08 33.1 10.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM81159.1 - 4.9e-08 33.2 10.3 1.4e-07 31.8 10.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFM81159.1 - 5.1e-08 32.6 10.4 1.5e-07 31.2 10.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM81159.1 - 1.5e-07 31.2 6.4 2.9e-07 30.2 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM81159.1 - 1.1e-05 25.2 8.4 3.1e-05 23.7 8.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFM81159.1 - 3.2e-05 23.9 3.4 3.2e-05 23.9 3.4 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM81159.1 - 0.00065 19.6 9.6 0.0015 18.4 9.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 KFM81159.1 - 0.0018 18.2 5.9 0.0043 17.0 5.9 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 KFM81159.1 - 0.0032 17.7 10.5 0.016 15.5 10.5 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFM81159.1 - 0.0033 17.5 8.3 0.0091 16.1 8.3 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KFM81159.1 - 0.0085 16.1 3.1 0.023 14.8 3.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger BLYB PF05289.11 KFM81159.1 - 0.13 12.5 0.5 0.32 11.2 0.1 1.9 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein zf-C3HC4_4 PF15227.6 KFM81159.1 - 0.13 12.4 10.7 0.42 10.8 10.7 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFM81159.1 - 4.2 7.2 7.7 11 5.9 7.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF481 PF04338.12 KFM81160.1 - 0.034 14.2 0.3 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF481 DUF2163 PF09931.9 KFM81160.1 - 0.035 14.3 0.1 0.076 13.2 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) Halogen_Hydrol PF10112.9 KFM81160.1 - 7.1 6.6 13.5 0.82 9.7 0.4 2.7 2 1 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RRM_1 PF00076.22 KFM81161.1 - 5.6e-19 67.7 0.0 8e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFM81161.1 - 0.00024 21.1 1.0 0.00084 19.4 0.0 2.3 3 0 0 3 3 3 1 Limkain b1 Apt1 PF10351.9 KFM81161.1 - 0.00031 19.7 14.6 0.00037 19.5 14.6 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain RRM_occluded PF16842.5 KFM81161.1 - 0.00067 19.5 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_8 PF11835.8 KFM81161.1 - 0.026 14.7 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain RRM_3 PF08777.11 KFM81161.1 - 0.089 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif NPR3 PF03666.13 KFM81161.1 - 0.13 11.0 12.2 0.19 10.5 12.2 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mem_trans PF03547.18 KFM81161.1 - 0.18 10.2 2.2 0.16 10.4 2.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Ndc1_Nup PF09531.10 KFM81161.1 - 2 7.0 16.5 2.6 6.6 16.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KFM81161.1 - 3.3 6.4 14.5 4.2 6.0 14.5 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KFM81161.1 - 5.8 5.3 28.3 7.2 5.0 28.3 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 KFM81161.1 - 5.9 6.0 5.2 6.4 5.9 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TK PF00265.18 KFM81162.1 - 4.8e-68 228.5 0.3 5.5e-68 228.3 0.3 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 KFM81162.1 - 0.00016 21.7 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFM81162.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Herpes_ori_bp PF02399.15 KFM81162.1 - 0.048 11.7 0.0 0.067 11.2 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Zn_ribbon_SprT PF17283.2 KFM81162.1 - 0.16 11.9 0.1 0.16 11.9 0.1 1.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF4065 PF13274.6 KFM81163.1 - 0.059 14.3 0.2 0.13 13.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) PX PF00787.24 KFM81164.1 - 1.5e-08 34.6 0.2 1.9e-08 34.3 0.2 1.1 1 0 0 1 1 1 1 PX domain EF-hand_4 PF12763.7 KFM81165.1 - 0.0034 17.3 0.0 0.0043 17.0 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand APG6_N PF17675.1 KFM81166.1 - 2.5e-05 24.8 1.7 2.8e-05 24.7 1.7 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KFM81166.1 - 0.0013 19.0 4.0 0.0022 18.2 4.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Leu_zip PF15294.6 KFM81166.1 - 0.0015 18.1 3.8 0.0018 17.8 3.8 1.1 1 0 0 1 1 1 1 Leucine zipper DivIC PF04977.15 KFM81166.1 - 0.0047 16.7 2.3 0.0047 16.7 2.3 2.2 1 1 1 2 2 2 1 Septum formation initiator ATG16 PF08614.11 KFM81166.1 - 0.012 15.9 10.5 0.016 15.4 10.5 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Tho2 PF11262.8 KFM81166.1 - 0.025 13.8 6.3 0.035 13.3 6.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4200 PF13863.6 KFM81166.1 - 0.047 14.1 13.6 0.086 13.2 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SOGA PF11365.8 KFM81166.1 - 0.064 14.4 4.7 0.064 14.4 4.7 1.6 2 0 0 2 2 1 0 Protein SOGA FlaC_arch PF05377.11 KFM81166.1 - 0.079 13.4 1.7 0.079 13.4 1.7 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Cnn_1N PF07989.11 KFM81166.1 - 0.14 12.3 8.7 0.24 11.6 8.7 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 TSNAXIP1_N PF15739.5 KFM81166.1 - 0.18 12.2 6.2 0.29 11.5 6.2 1.2 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus GAS PF13851.6 KFM81166.1 - 0.19 11.1 11.6 0.24 10.7 11.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 KFM81166.1 - 0.21 12.0 9.1 2.9 8.4 9.1 2.2 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 KFM81166.1 - 0.22 12.2 7.4 0.34 11.6 7.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF4795 PF16043.5 KFM81166.1 - 0.23 11.0 7.6 0.34 10.5 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4140 PF13600.6 KFM81166.1 - 0.26 11.8 3.4 5.1 7.6 0.0 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seadorna_VP6 PF07407.11 KFM81166.1 - 0.31 9.9 1.6 0.39 9.6 1.6 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein CENP-H PF05837.12 KFM81166.1 - 0.57 10.6 9.2 0.56 10.6 8.2 1.5 2 0 0 2 2 1 0 Centromere protein H (CENP-H) SlyX PF04102.12 KFM81166.1 - 0.92 10.2 4.1 7 7.4 1.3 2.2 1 1 1 2 2 2 0 SlyX Csm1_N PF18504.1 KFM81166.1 - 1.3 9.4 10.5 1.6 9.1 6.1 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain FlgM PF04316.13 KFM81167.1 - 10 6.6 7.6 11 6.5 1.1 2.7 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM RPEL PF02755.15 KFM81168.1 - 4.6e-19 67.5 7.7 5.2e-09 35.5 1.6 4.0 3 0 0 3 3 3 3 RPEL repeat SAP PF02037.27 KFM81168.1 - 3.5e-13 49.0 0.1 3.5e-13 49.0 0.1 1.8 2 0 0 2 2 2 1 SAP domain PH_3 PF14593.6 KFM81169.1 - 2.7e-45 152.7 0.0 4.2e-45 152.1 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFM81169.1 - 0.0022 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1870 PF08965.10 KFM81169.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) NYN PF01936.18 KFM81170.1 - 0.00098 19.6 0.0 0.0014 19.1 0.0 1.3 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 KFM81172.1 - 1.1e-19 70.0 0.0 6.2e-10 38.8 0.0 3.9 4 0 0 4 4 4 2 OST-HTH/LOTUS domain RRM_1 PF00076.22 KFM81172.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OST-HTH PF12872.7 KFM81173.1 - 1.4e-33 114.6 2.0 2.2e-09 37.0 0.1 5.2 5 0 0 5 5 5 3 OST-HTH/LOTUS domain MBDa PF16564.5 KFM81173.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 p55-binding region of Methyl-CpG-binding domain proteins MBD Cyclin_C PF02984.19 KFM81174.1 - 4.9e-36 123.4 2.3 6.4e-36 123.0 2.3 1.2 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KFM81174.1 - 2e-16 59.9 0.5 3.1e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF2279 PF10043.9 KFM81174.1 - 0.1 13.4 0.0 0.16 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) Cyclin_C_2 PF16899.5 KFM81174.1 - 0.12 12.7 0.8 0.17 12.3 0.8 1.5 1 1 0 1 1 1 0 Cyclin C-terminal domain RVT_1 PF00078.27 KFM81176.1 - 1.5e-41 142.3 0.0 2.1e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 KFM81177.1 - 1.1e-31 108.3 7.6 5.3e-09 36.6 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM81177.1 - 1.8e-12 47.4 0.6 1.7e-07 31.4 0.1 2.9 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM81177.1 - 2.7e-06 27.4 0.0 0.031 14.2 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFM81177.1 - 0.00024 20.5 0.0 0.31 10.3 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KFM81177.1 - 0.0019 17.2 0.0 0.15 11.0 0.0 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFM81177.1 - 0.0085 14.8 0.1 0.59 8.7 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KFM81177.1 - 0.012 14.6 0.2 3.2 6.6 0.1 2.0 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 KFM81177.1 - 0.03 14.3 0.1 4.6 7.3 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat FAD_binding_9 PF08021.11 KFM81177.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain TFIIIC_delta PF12657.7 KFM81177.1 - 0.19 11.6 1.0 15 5.5 0.0 2.4 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 KFM81178.1 - 5.1e-34 115.7 15.2 3.8e-09 37.0 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM81178.1 - 4.2e-14 52.6 2.8 7.6e-05 22.9 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KFM81178.1 - 1.3e-12 48.0 0.1 3.2e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 KFM81178.1 - 0.0003 19.9 0.0 0.0032 16.5 0.0 2.3 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KFM81178.1 - 0.049 13.6 0.0 0.81 9.6 0.0 2.4 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat PD40 PF07676.12 KFM81178.1 - 0.073 13.0 0.0 0.92 9.5 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KFM81178.1 - 0.1 11.3 0.1 1.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Chitin_bind_4 PF00379.23 KFM81179.1 - 2.9e-10 40.5 6.9 4.6e-10 39.9 6.9 1.3 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM81180.1 - 6.5e-10 39.4 6.4 9.5e-10 38.9 6.4 1.2 1 0 0 1 1 1 1 Insect cuticle protein LETM1 PF07766.13 KFM81182.1 - 9.8e-64 215.3 0.0 1.1e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 LETM1-like protein HLH PF00010.26 KFM81184.1 - 6e-10 38.9 1.0 1e-09 38.2 0.1 1.7 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Astacin PF01400.24 KFM81185.1 - 1e-59 201.4 0.0 1.2e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 KFM81185.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFM81185.1 - 0.2 11.5 3.0 0.4 10.5 1.3 2.1 2 1 0 3 3 3 0 Matrixin Peptidase_M57 PF12388.8 KFM81185.1 - 0.21 11.2 0.2 0.34 10.5 0.2 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Astacin PF01400.24 KFM81186.1 - 2.9e-62 209.7 0.2 3.4e-62 209.5 0.2 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 KFM81186.1 - 0.0095 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFM81186.1 - 0.0099 15.7 2.1 0.2 11.5 1.3 2.7 2 1 0 3 3 3 1 Matrixin Peptidase_M66 PF10462.9 KFM81186.1 - 0.11 11.4 1.6 0.21 10.5 1.3 1.4 1 1 1 2 2 2 0 Peptidase M66 Peptidase_M57 PF12388.8 KFM81186.1 - 0.17 11.5 0.3 0.32 10.6 0.3 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase tRNA_synthFbeta PF17759.1 KFM81187.1 - 2.2e-50 171.1 0.0 3.2e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KFM81187.1 - 5.6e-34 116.2 0.4 7.2e-32 109.5 0.1 2.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KFM81187.1 - 1.9e-29 102.5 0.2 3.4e-29 101.7 0.2 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFM81187.1 - 2e-18 66.4 0.0 3.5e-16 59.2 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetase B5 domain DUF2740 PF10872.8 KFM81187.1 - 0.16 11.9 0.1 0.4 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) MRP-S23 PF10484.9 KFM81188.1 - 1.7e-15 57.4 0.0 1.9e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 DNA_pol_B PF00136.21 KFM81190.1 - 2.1e-95 320.1 0.0 3.8e-95 319.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFM81190.1 - 1.5e-12 47.3 1.7 1.5e-12 47.3 1.7 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFM81190.1 - 0.0082 16.6 1.1 0.051 14.0 1.1 2.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF1922 PF09082.10 KFM81191.1 - 1.8 8.9 4.4 4 7.8 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1922) Transposase_1 PF01359.18 KFM81196.1 - 0.00085 19.1 0.1 0.0011 18.8 0.1 1.2 1 0 0 1 1 1 1 Transposase (partial DDE domain) DUF1759 PF03564.15 KFM81197.1 - 2.2e-10 40.6 0.0 2.5e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) PAC3 PF10178.9 KFM81197.1 - 0.041 14.0 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 DNA_pol3_delt_C PF14840.6 KFM81197.1 - 0.062 13.6 0.2 0.078 13.3 0.2 1.2 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term MAPEG PF01124.18 KFM81199.1 - 5.7e-24 84.5 0.6 7e-24 84.2 0.6 1.1 1 0 0 1 1 1 1 MAPEG family SOCS_box PF07525.16 KFM81200.1 - 3.4e-05 24.1 0.7 8.7e-05 22.8 0.7 1.7 1 0 0 1 1 1 1 SOCS box Drf_FH3 PF06367.16 KFM81201.1 - 3.2e-08 33.4 0.0 4.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFM81201.1 - 0.00026 20.6 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain FH2 PF02181.23 KFM81202.1 - 3.3e-80 270.0 9.2 3.3e-80 270.0 9.2 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain DUF4757 PF15949.5 KFM81203.1 - 3e-14 53.8 6.8 3e-14 53.8 6.8 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF4757) PDZ PF00595.24 KFM81203.1 - 3.1e-11 43.5 0.0 7.9e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM81203.1 - 7.2e-08 32.2 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 KFM81203.1 - 4.1e-06 26.9 13.6 4.1e-06 26.9 13.6 2.4 2 0 0 2 2 2 1 LIM domain PDZ_2 PF13180.6 KFM81203.1 - 0.004 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DUF3199 PF11436.8 KFM81203.1 - 0.042 13.9 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) Importin_rep_6 PF18829.1 KFM81203.1 - 0.054 13.6 2.0 0.26 11.4 2.0 2.2 1 0 0 1 1 1 0 Importin repeat 6 FPL PF09758.9 KFM81207.1 - 7.2e-22 78.0 1.8 8.8e-22 77.7 1.8 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Flg_bbr_C PF06429.13 KFM81209.1 - 0.064 13.4 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal Arc_PepC_II PF06847.11 KFM81209.1 - 0.22 12.1 0.5 0.37 11.3 0.5 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Ras PF00071.22 KFM81211.1 - 2.5e-38 131.2 0.0 3e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM81211.1 - 1e-27 96.7 0.0 1.4e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM81211.1 - 2.5e-10 40.1 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM81211.1 - 1.6e-06 27.6 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KFM81211.1 - 0.0012 19.1 0.0 0.0028 17.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFM81211.1 - 0.0013 18.2 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region GTP_EFTU PF00009.27 KFM81211.1 - 0.0026 17.3 0.0 0.087 12.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFM81211.1 - 0.0035 17.2 0.0 0.79 9.5 0.0 2.4 1 1 2 3 3 3 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KFM81211.1 - 0.0039 17.3 0.0 0.0055 16.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3283 PF11686.8 KFM81211.1 - 0.017 15.0 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) AAA_24 PF13479.6 KFM81211.1 - 0.027 14.2 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFM81211.1 - 0.031 13.7 0.0 0.18 11.2 0.0 2.1 2 1 1 3 3 3 0 Bacterial TniB protein MMR_HSR1_Xtn PF16897.5 KFM81211.1 - 0.041 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF815 PF05673.13 KFM81211.1 - 0.054 12.7 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KFM81211.1 - 0.06 13.1 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DLIC PF05783.11 KFM81211.1 - 0.068 12.0 0.0 2.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) TsaE PF02367.17 KFM81211.1 - 0.079 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ISP1_C PF18161.1 KFM81211.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 ISP1 C-terminal Sigma54_activat PF00158.26 KFM81211.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 KFM81211.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.6 KFM81211.1 - 0.16 10.7 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFM81211.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM81211.1 - 0.18 12.1 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KFM81211.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-C2H2 PF00096.26 KFM81212.1 - 1.4e-26 91.4 48.6 2.5e-05 24.5 0.7 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81212.1 - 8.7e-26 88.4 44.5 0.00016 22.2 0.5 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM81212.1 - 9.2e-25 85.9 46.6 6e-06 26.4 0.4 7.2 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM81212.1 - 1.4e-20 73.0 28.7 0.00043 20.5 0.1 6.4 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM81212.1 - 2.2e-14 53.3 36.4 8.7e-05 22.8 0.3 6.5 6 1 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM81212.1 - 8.6e-07 28.8 38.4 0.032 14.2 1.1 6.6 6 1 0 6 6 6 4 C2H2-type zinc finger zf-Di19 PF05605.12 KFM81212.1 - 1.9e-05 24.8 26.5 0.28 11.5 6.6 4.3 2 2 3 5 5 5 5 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.22 KFM81212.1 - 7.6e-05 22.5 16.7 0.0023 17.8 0.2 5.0 2 2 3 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.7 KFM81212.1 - 0.0001 22.5 29.2 0.4 11.0 0.5 6.0 1 1 5 6 6 6 2 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM81212.1 - 0.0081 16.1 2.2 0.0081 16.1 2.2 3.4 4 0 0 4 4 3 1 Adenylate kinase, active site lid C1_4 PF07975.12 KFM81212.1 - 0.012 15.8 16.4 7.2 6.9 0.5 4.3 3 1 1 4 4 4 0 TFIIH C1-like domain zf_UBZ PF18439.1 KFM81212.1 - 0.015 14.9 16.6 0.51 10.0 0.0 5.9 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM81212.1 - 0.062 13.4 17.4 3.1 8.0 0.5 4.9 3 2 3 6 6 6 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM81212.1 - 0.07 13.9 17.6 0.65 10.8 2.0 3.5 2 1 1 3 3 3 0 zinc-ribbon family zf-H2C2_5 PF13909.6 KFM81212.1 - 0.12 12.2 0.2 0.12 12.2 0.2 6.9 6 1 0 6 6 6 0 C2H2-type zinc-finger domain GAGA PF09237.11 KFM81212.1 - 0.13 12.1 0.4 0.13 12.1 0.4 3.8 2 2 2 4 4 4 0 GAGA factor zf-C2H2_9 PF16293.5 KFM81212.1 - 0.14 12.0 15.2 35 4.3 0.3 6.1 5 1 2 7 7 6 0 C2H2 type zinc-finger (1 copy) Prok-RING_1 PF14446.6 KFM81212.1 - 0.17 11.8 15.7 14 5.7 0.1 5.9 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 Zn-C2H2_12 PF18112.1 KFM81212.1 - 0.25 11.8 25.7 2.6 8.6 0.0 6.8 6 2 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_8 PF15909.5 KFM81212.1 - 0.3 11.4 21.0 3.1 8.2 3.6 3.5 1 1 2 3 3 3 0 C2H2-type zinc ribbon FYDLN_acid PF09538.10 KFM81212.1 - 0.49 11.1 10.7 0.9 10.2 0.0 4.3 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) HNH_5 PF14279.6 KFM81212.1 - 0.53 10.2 17.8 40 4.2 1.0 5.8 4 2 0 4 4 4 0 HNH endonuclease XPA_N PF01286.18 KFM81212.1 - 0.67 10.1 18.6 7.6 6.7 0.0 6.0 6 0 0 6 6 6 0 XPA protein N-terminal DUF2256 PF10013.9 KFM81212.1 - 0.88 9.7 18.4 46 4.2 0.1 5.8 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFM81212.1 - 0.89 9.2 22.3 12 5.6 0.0 5.9 4 1 1 5 5 5 0 MYST family zinc finger domain Zn_ribbon_SprT PF17283.2 KFM81212.1 - 0.97 9.4 19.0 1.2 9.1 4.9 4.0 1 1 2 3 3 3 0 SprT-like zinc ribbon domain zf-BED PF02892.15 KFM81212.1 - 2.2 8.3 33.5 7.9 6.6 2.4 6.1 2 1 3 5 5 5 0 BED zinc finger zf-C2H2_11 PF16622.5 KFM81212.1 - 3 7.7 31.9 0.74 9.6 0.9 5.9 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-RRPl_C4 PF17026.5 KFM81212.1 - 3 8.0 17.7 20 5.3 10.7 3.3 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_3rep PF18868.1 KFM81212.1 - 3.5 8.3 17.7 2.8 8.6 1.7 4.5 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats zinc-ribbons_6 PF07191.12 KFM81212.1 - 8.2 6.5 17.0 5.4e+02 0.7 9.8 4.2 1 1 1 2 2 2 0 zinc-ribbons zf-H2C2_2 PF13465.6 KFM81213.1 - 1.9e-29 100.7 39.0 1.7e-06 28.2 2.1 6.3 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM81213.1 - 8.9e-28 95.2 43.9 8.4e-06 26.0 1.3 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81213.1 - 5.7e-23 79.6 40.8 0.00012 22.6 1.1 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM81213.1 - 3.4e-19 68.6 31.1 0.00092 19.4 0.1 6.6 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM81213.1 - 6.7e-16 58.1 35.0 0.0024 18.2 1.3 6.7 7 0 0 7 7 6 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM81213.1 - 4.1e-14 52.2 35.4 0.01 15.8 1.8 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger BolA PF01722.18 KFM81213.1 - 1.6e-13 50.8 4.3 0.0017 18.6 0.2 4.1 3 1 1 4 4 4 4 BolA-like protein zf_UBZ PF18439.1 KFM81213.1 - 1.3e-08 34.3 19.6 0.99 9.1 0.1 6.3 6 0 0 6 6 6 5 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM81213.1 - 1.1e-05 24.9 14.1 1.5 8.5 0.3 5.7 4 1 2 6 6 6 3 MYST family zinc finger domain Tox-HNH-HHH PF15637.6 KFM81213.1 - 2.5e-05 24.4 0.2 0.037 14.2 0.0 2.8 1 1 1 3 3 3 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif GAGA PF09237.11 KFM81213.1 - 0.00058 19.6 10.0 0.35 10.7 0.1 4.4 3 2 2 5 5 5 2 GAGA factor C1_4 PF07975.12 KFM81213.1 - 0.0012 19.1 24.3 0.34 11.2 0.4 4.1 2 2 2 4 4 4 3 TFIIH C1-like domain Zn_ribbon_SprT PF17283.2 KFM81213.1 - 0.013 15.4 16.4 0.052 13.5 2.8 4.3 2 1 2 4 4 4 0 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM81213.1 - 0.023 15.4 16.6 0.9 10.3 1.4 3.4 1 1 0 3 3 3 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFM81213.1 - 0.038 14.1 22.9 0.043 13.9 3.7 5.0 4 3 2 6 6 5 0 Zinc ribbon domain XPA_N PF01286.18 KFM81213.1 - 0.039 14.0 23.1 9.8 6.3 0.2 6.4 6 0 0 6 6 6 0 XPA protein N-terminal zf-RRPl_C4 PF17026.5 KFM81213.1 - 0.17 12.0 16.2 0.24 11.5 3.9 3.1 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_2 PF12756.7 KFM81213.1 - 0.51 10.7 25.0 15 6.0 1.5 5.8 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 KFM81213.1 - 0.58 10.3 18.3 7.5 6.7 0.2 5.2 2 2 4 6 6 6 0 KIAA1045 RING finger UBZ_FAAP20 PF15750.5 KFM81213.1 - 1.4 8.9 15.8 21 5.1 0.1 5.3 5 0 0 5 5 5 0 Ubiquitin-binding zinc-finger zf-AN1 PF01428.16 KFM81213.1 - 1.5 9.1 30.5 3.7 7.8 2.2 6.3 5 1 1 6 6 6 0 AN1-like Zinc finger FYVE PF01363.21 KFM81213.1 - 1.5 9.0 31.1 8.7 6.6 7.9 5.0 2 2 1 4 4 4 0 FYVE zinc finger Prok-RING_1 PF14446.6 KFM81213.1 - 1.6 8.7 20.8 12 6.0 0.1 5.9 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 zf-Paramyx-P PF13008.7 KFM81213.1 - 2.6 7.6 14.4 17 5.0 1.3 4.6 3 2 0 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein Ta0938 PF11494.8 KFM81213.1 - 3.1 8.1 9.7 13 6.1 0.6 4.1 2 2 2 4 4 4 0 Ta0938 PIF1 PF05970.14 KFM81214.1 - 7.1e-17 61.6 0.2 8.9e-17 61.3 0.2 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFM81214.1 - 0.0011 18.7 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KFM81214.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ResIII PF04851.15 KFM81214.1 - 0.016 15.2 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Thoc2 PF11732.8 KFM81215.1 - 0.019 15.0 0.4 0.021 14.9 0.4 1.2 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Thioredoxin_6 PF13848.6 KFM81217.1 - 1.2e-13 51.4 0.1 2e-13 50.6 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain E2F_TDP PF02319.20 KFM81218.1 - 3.9e-24 84.5 0.2 8.6e-24 83.4 0.2 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 KFM81218.1 - 6.1e-24 84.2 1.8 9.2e-24 83.6 0.2 2.1 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain DUF4682 PF15733.5 KFM81218.1 - 2.4 8.7 7.6 1.2 9.7 2.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4682) Peptidase_M14 PF00246.24 KFM81219.1 - 2.6e-90 303.1 0.0 3.1e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFM81219.1 - 1.3e-14 54.3 0.2 2.3e-14 53.5 0.2 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Lentiviral_Tat PF02998.14 KFM81219.1 - 0.18 11.9 0.4 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 Lentiviral Tat protein Peptidase_S8 PF00082.22 KFM81220.1 - 3.6e-49 167.6 4.2 4.7e-49 167.3 4.2 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFM81220.1 - 1.8e-23 82.3 0.0 4e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFM81220.1 - 6.8e-19 68.4 0.3 1.3e-18 67.5 0.3 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KFM81220.1 - 0.078 13.5 0.4 0.14 12.6 0.4 1.4 1 0 0 1 1 1 0 N-terminal of Subtilase family OmpA_membrane PF01389.17 KFM81220.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 OmpA-like transmembrane domain BAMBI PF06211.12 KFM81221.1 - 1.9e-07 31.3 5.5 4.8e-07 30.0 5.5 1.7 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Activin_recp PF01064.23 KFM81221.1 - 0.001 20.1 9.8 0.001 20.1 9.8 1.8 2 0 0 2 2 2 1 Activin types I and II receptor domain DUF4064 PF13273.6 KFM81221.1 - 0.0052 17.0 0.2 0.0052 17.0 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) CrgA PF06781.12 KFM81221.1 - 0.039 14.0 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Cell division protein CrgA SMC_Nse1 PF07574.13 KFM81222.1 - 1.1e-20 74.4 0.0 3.6e-18 66.1 0.0 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex DUF4373 PF14297.6 KFM81222.1 - 0.086 13.6 0.3 0.27 12.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4373) Peptidase_A22B PF04258.13 KFM81224.1 - 5.5e-70 236.1 21.4 1e-69 235.2 21.4 1.4 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 KFM81224.1 - 5e-07 29.6 0.0 9.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 PA domain RPN7 PF10602.9 KFM81225.1 - 8.2e-60 201.5 2.9 1.2e-59 200.9 2.9 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFM81225.1 - 3.9e-17 62.7 0.4 3.5e-16 59.6 0.0 2.3 2 0 0 2 2 2 1 PCI domain Nairo_nucleo PF02477.15 KFM81225.1 - 0.064 12.1 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleocapsid N protein HTH_11 PF08279.12 KFM81225.1 - 0.089 12.8 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 HTH domain DUF4536 PF15055.6 KFM81226.1 - 1e-06 28.9 1.1 1.4e-06 28.4 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) MYT1 PF08474.11 KFM81230.1 - 3.8e-06 27.0 0.1 4e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Myelin transcription factor 1 zf-C2HC PF01530.18 KFM81232.1 - 2e-24 85.5 22.1 2.3e-15 56.4 8.8 3.2 3 0 0 3 3 3 3 Zinc finger, C2HC type Anti-TRAP PF15777.5 KFM81232.1 - 0.052 13.5 0.4 0.052 13.5 0.4 1.7 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Mod_r PF07200.13 KFM81233.1 - 0.0018 18.4 1.3 0.0023 18.0 1.3 1.3 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein zf-C4H2 PF10146.9 KFM81233.1 - 0.0045 17.3 0.3 0.0045 17.3 0.3 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein Retrotrans_gag PF03732.17 KFM81233.1 - 0.013 15.8 1.7 0.075 13.3 0.7 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein GAS PF13851.6 KFM81233.1 - 0.015 14.7 0.6 0.018 14.4 0.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 KFM81233.1 - 0.017 15.4 0.3 0.017 15.4 0.3 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DivIC PF04977.15 KFM81233.1 - 0.022 14.5 0.3 0.026 14.3 0.3 1.2 1 0 0 1 1 1 0 Septum formation initiator TMF_TATA_bd PF12325.8 KFM81233.1 - 0.024 14.8 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KFM81233.1 - 0.04 13.9 0.2 0.051 13.6 0.2 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KFM81233.1 - 0.093 13.2 1.2 0.11 12.9 1.2 1.3 1 1 0 1 1 1 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 KFM81233.1 - 0.22 11.6 3.4 0.39 10.8 2.2 2.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 RAWUL PF16207.5 KFM81234.1 - 4e-13 49.8 0.4 7.3e-13 49.0 0.4 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFM81234.1 - 3e-11 43.0 7.4 8.8e-11 41.5 7.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM81234.1 - 3.3e-10 39.7 8.4 1.4e-09 37.7 8.4 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM81234.1 - 2.6e-07 30.5 4.5 2.6e-07 30.5 4.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM81234.1 - 1.1e-05 25.5 6.6 3.6e-05 23.8 6.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFM81234.1 - 1.1e-05 25.3 7.9 1.1e-05 25.3 7.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM81234.1 - 8.7e-05 22.3 8.2 8.7e-05 22.3 8.2 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM81234.1 - 0.00012 22.3 7.1 0.00012 22.3 7.1 2.4 2 1 0 2 2 2 1 Ring finger domain zf-Nse PF11789.8 KFM81234.1 - 0.0043 16.8 3.6 0.01 15.6 3.6 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 KFM81234.1 - 0.0099 15.8 4.6 0.045 13.7 4.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM81234.1 - 0.018 14.9 7.7 0.07 13.0 7.5 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFM81234.1 - 0.92 9.8 12.6 0.13 12.5 6.8 2.5 2 2 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KFM81234.1 - 7.8 6.5 12.5 0.13 12.1 4.6 2.2 3 0 0 3 3 2 0 zf-RING of BARD1-type protein CBFD_NFYB_HMF PF00808.23 KFM81235.1 - 0.00079 19.7 0.1 0.0014 18.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone U1snRNP70_N PF12220.8 KFM81237.1 - 1.1e-27 96.5 3.8 1.8e-27 95.8 3.8 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KFM81237.1 - 8e-20 70.4 0.0 1.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM81237.1 - 0.022 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDA1 PF10172.9 KFM81238.1 - 7.9e-25 86.9 1.9 1.3e-24 86.2 1.9 1.4 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase Glyco_hydro_18 PF00704.28 KFM81239.1 - 1.7e-11 44.4 4.0 2.8e-11 43.7 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 KFM81239.1 - 1.7e-10 40.9 2.8 3.3e-10 40.0 2.8 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain FSA_C PF10479.9 KFM81239.1 - 0.3 9.2 5.1 0.36 8.9 5.1 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 KFM81239.1 - 0.58 8.1 2.2 0.78 7.6 2.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 KFM81239.1 - 3 7.8 37.8 4.7 7.2 37.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_hydro_18 PF00704.28 KFM81240.1 - 2.3e-34 119.5 0.0 2.5e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PDCD9 PF07147.12 KFM81242.1 - 2.9e-84 283.9 1.0 7.5e-84 282.5 1.0 1.6 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) ESF1 PF18209.1 KFM81242.1 - 0.24 11.3 2.4 0.94 9.4 0.2 2.6 2 0 0 2 2 2 0 Embryo surrounding factor 1 MRP-S23 PF10484.9 KFM81242.1 - 0.26 11.6 3.1 1.7 8.9 0.2 2.6 2 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 Suf PF05843.14 KFM81243.1 - 8.8e-78 262.3 9.6 9.3e-77 258.9 0.3 3.6 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KFM81243.1 - 8.4e-06 25.1 0.6 0.18 10.9 0.0 4.0 2 1 2 4 4 4 2 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.11 KFM81243.1 - 0.53 10.4 2.1 18 5.5 0.0 3.5 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 6 Mad3_BUB1_I PF08311.12 KFM81243.1 - 6.5 6.8 7.8 54 3.8 4.0 4.1 3 1 0 3 3 3 0 Mad3/BUB1 homology region 1 TLD PF07534.16 KFM81244.1 - 4.4e-35 120.9 0.4 1.1e-34 119.6 0.4 1.7 2 0 0 2 2 2 1 TLD LysM PF01476.20 KFM81244.1 - 4.7e-10 39.4 0.0 2.6e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 LysM domain GRAM PF02893.20 KFM81244.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 GRAM domain HipN PF18253.1 KFM81244.1 - 0.12 12.1 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain FAD_binding_2 PF00890.24 KFM81245.1 - 5.6e-105 351.8 0.1 7.4e-105 351.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KFM81245.1 - 3.1e-40 137.1 0.3 4.5e-40 136.6 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term CoaE PF01121.20 KFM81247.1 - 9.9e-16 57.9 0.0 2.1e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Dephospho-CoA kinase CTP_transf_like PF01467.26 KFM81247.1 - 3.6e-09 37.0 0.0 3.9e-08 33.6 0.0 2.2 1 1 1 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 KFM81247.1 - 0.035 14.0 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 FAD synthetase Thg1 PF04446.12 KFM81248.1 - 6.8e-53 178.0 0.5 1.1e-52 177.3 0.5 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KFM81248.1 - 5.5e-43 146.0 0.9 9.8e-43 145.2 0.9 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain TPH PF13868.6 KFM81249.1 - 3e-40 137.8 141.7 3e-40 137.8 141.7 2.3 1 1 0 2 2 2 1 Trichohyalin-plectin-homology domain PSS PF03034.15 KFM81251.1 - 6.8e-93 311.4 8.7 6.8e-93 311.4 8.7 1.3 2 0 0 2 2 2 1 Phosphatidyl serine synthase Transferrin PF00405.17 KFM81252.1 - 3.8e-36 124.9 0.0 5e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Transferrin Phosphonate-bd PF12974.7 KFM81252.1 - 6.2e-11 42.4 0.0 1.8e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Transferrin PF00405.17 KFM81253.1 - 2.2e-68 230.9 0.1 2.4e-68 230.7 0.1 1.0 1 0 0 1 1 1 1 Transferrin Phosphonate-bd PF12974.7 KFM81253.1 - 2.8e-10 40.2 0.0 1e-09 38.4 0.0 1.9 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Galactosyl_T PF01762.21 KFM81254.1 - 6.8e-48 163.1 0.0 9.5e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF4307 PF14155.6 KFM81254.1 - 0.05 13.4 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Glyco_transf_29 PF00777.18 KFM81255.1 - 7.4e-14 51.8 0.0 7.9e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) LRR_6 PF13516.6 KFM81262.1 - 1.2e-14 53.1 18.8 0.029 14.4 0.1 9.4 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 KFM81262.1 - 2.1e-07 31.1 14.4 0.29 11.6 0.3 6.2 4 1 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM81262.1 - 3.7e-06 26.6 13.2 0.016 14.9 0.0 5.8 4 1 1 5 5 5 3 Leucine rich repeat F-box PF00646.33 KFM81262.1 - 9.1e-05 22.2 0.1 0.00051 19.8 0.1 2.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFM81262.1 - 0.00033 20.5 0.1 0.0018 18.1 0.1 2.3 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KFM81262.1 - 0.36 11.6 24.1 0.61 10.9 0.0 8.0 10 0 0 10 10 10 0 Leucine Rich Repeat RNA_pol_Rbc25 PF08292.12 KFM81263.1 - 6.9e-39 133.0 0.1 1.1e-38 132.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KFM81263.1 - 8.6e-16 58.1 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 TMEM154 PF15102.6 KFM81264.1 - 0.00086 19.2 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family fn3 PF00041.21 KFM81264.1 - 0.0051 17.1 0.2 0.015 15.6 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain EphA2_TM PF14575.6 KFM81264.1 - 0.0055 17.6 0.1 0.01 16.7 0.1 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 KFM81264.1 - 0.012 16.4 0.3 0.023 15.4 0.3 1.7 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Baculo_11_kDa PF06143.11 KFM81264.1 - 0.012 15.1 0.6 0.023 14.3 0.6 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM51 PF15345.6 KFM81264.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Orf78 PF06024.12 KFM81264.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) ECSCR PF15820.5 KFM81264.1 - 0.019 14.8 0.1 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator MAP17 PF15807.5 KFM81264.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FAM176 PF14851.6 KFM81264.1 - 0.024 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Ninjurin PF04923.12 KFM81264.1 - 0.042 13.8 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Ninjurin Conotoxin PF02950.17 KFM81264.1 - 0.045 14.8 0.1 0.086 13.9 0.1 1.4 1 0 0 1 1 1 0 Conotoxin SIT PF15330.6 KFM81264.1 - 0.076 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF5408 PF17402.2 KFM81264.1 - 0.084 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5408) PRIMA1 PF16101.5 KFM81264.1 - 0.087 12.9 0.0 0.087 12.9 0.0 2.2 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 DUF4834 PF16118.5 KFM81264.1 - 0.11 13.5 0.0 0.19 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 KFM81264.1 - 0.18 9.7 0.0 0.22 9.4 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1180 PF06679.12 KFM81264.1 - 4.9 7.5 6.1 0.44 11.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) C2-set_2 PF08205.12 KFM81266.1 - 9.7e-10 38.4 0.0 8.4e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFM81266.1 - 9.8e-10 38.9 0.0 1.5e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM81266.1 - 3.2e-07 30.6 0.1 4.2e-06 27.0 0.0 2.1 1 1 1 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFM81266.1 - 0.00013 22.1 0.0 0.26 11.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM81266.1 - 0.00048 20.1 0.0 0.028 14.5 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain C2-set PF05790.15 KFM81266.1 - 0.039 14.1 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin C2-set domain MOSC_N PF03476.16 KFM81269.1 - 3e-21 75.5 0.0 5.1e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KFM81269.1 - 7.1e-19 68.1 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 MOSC domain I-set PF07679.16 KFM81270.1 - 5.5e-48 161.0 0.0 2.5e-16 59.5 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM81270.1 - 6.7e-43 145.2 0.8 6.7e-15 55.5 0.0 3.8 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFM81270.1 - 2.1e-37 127.1 0.2 1.1e-10 41.5 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 KFM81270.1 - 7.5e-31 106.3 0.1 1.5e-11 44.5 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFM81270.1 - 3.3e-22 78.7 1.1 4.2e-07 30.1 0.0 6.9 4 3 0 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM81270.1 - 3e-07 29.9 0.0 0.7 9.5 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.12 KFM81270.1 - 3.5e-06 27.0 0.1 0.0035 17.4 0.0 3.1 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFM81270.1 - 8.6e-05 22.9 0.0 0.61 10.5 0.0 3.7 4 2 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM81270.1 - 9.5e-05 22.6 0.0 0.85 9.9 0.0 4.0 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFM81270.1 - 0.00011 22.2 0.0 0.55 10.3 0.0 3.6 3 1 0 3 3 3 2 C17orf99 Ig domain V-set_CD47 PF08204.11 KFM81270.1 - 0.00071 19.6 0.4 0.53 10.3 0.0 3.9 3 2 1 4 4 4 1 CD47 immunoglobulin-like domain Receptor_2B4 PF11465.8 KFM81270.1 - 0.0065 16.7 0.0 14 6.0 0.0 3.3 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 fn3 PF00041.21 KFM81271.1 - 6.7e-169 548.8 44.5 6.5e-15 55.2 0.0 13.3 13 0 0 13 13 13 13 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM81271.1 - 9.8e-27 93.4 30.0 0.0066 17.0 1.0 14.0 13 2 0 13 13 13 8 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM81271.1 - 6.1e-13 49.0 0.1 0.72 10.2 0.0 9.6 10 1 0 10 10 10 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFM81271.1 - 4.9e-09 36.4 3.9 16 5.9 0.3 9.6 10 1 0 10 10 10 1 Uncharacterised conserved protein (DUF2369) SusE PF14292.6 KFM81271.1 - 4.4e-05 23.7 6.6 0.036 14.3 0.5 5.3 4 1 1 5 5 5 1 SusE outer membrane protein Cadherin PF00028.17 KFM81271.1 - 0.0012 19.3 0.1 24 5.4 0.0 6.5 8 0 0 8 8 8 0 Cadherin domain fn3_4 PF16794.5 KFM81271.1 - 0.059 13.3 0.2 1.2e+02 2.7 0.0 5.2 6 0 0 6 6 6 0 Fibronectin-III type domain CBM_4_9 PF02018.17 KFM81271.1 - 0.22 11.8 2.5 1.1 9.6 0.4 3.3 2 1 0 3 3 3 0 Carbohydrate binding domain F5_F8_type_C PF00754.25 KFM81271.1 - 3.4 7.8 10.3 3.1 7.9 0.6 4.5 4 1 2 6 6 6 0 F5/8 type C domain LUC7 PF03194.15 KFM81272.1 - 1.9e-80 270.2 13.3 1.9e-80 270.2 13.3 2.0 2 1 0 2 2 2 1 LUC7 N_terminus FCH PF00611.23 KFM81272.1 - 0.011 16.0 0.3 0.011 16.0 0.3 2.8 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain DUF1664 PF07889.12 KFM81272.1 - 0.12 12.4 1.9 0.24 11.4 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KFM81272.1 - 0.13 12.5 5.2 0.058 13.7 2.2 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein Pribosyl_synth PF14572.6 KFM81273.1 - 5.6e-100 332.9 1.3 5.6e-100 332.9 1.3 1.5 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFM81273.1 - 3.2e-39 133.5 0.8 6.4e-39 132.5 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFM81273.1 - 0.0001 21.8 0.1 0.00019 21.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain IGFBP PF00219.18 KFM81276.1 - 0.76 10.5 9.5 1.5 9.5 9.5 1.6 1 1 0 1 1 1 0 Insulin-like growth factor binding protein FERM_N PF09379.10 KFM81278.1 - 1.5e-07 31.3 0.0 3.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 KFM81279.1 - 6.7e-13 48.9 0.3 7.5e-13 48.7 0.3 1.1 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PDZ PF00595.24 KFM81281.1 - 1.6e-39 134.1 0.1 3.4e-16 59.3 0.0 4.5 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFM81281.1 - 1.6e-30 104.7 0.1 8.4e-11 41.6 0.0 4.2 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KFM81281.1 - 2.7e-15 56.5 0.0 6.7e-06 26.4 0.0 3.5 3 0 0 3 3 3 3 PDZ domain DUF2894 PF11445.8 KFM81281.1 - 0.15 12.5 3.3 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) DUF4218 PF13960.6 KFM81282.1 - 0.0001 21.9 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) SSF PF00474.17 KFM81284.1 - 6.6e-10 38.4 4.5 9.3e-10 37.9 4.5 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 KFM81285.1 - 7.9e-26 90.8 8.7 1.8e-24 86.4 5.5 2.1 2 0 0 2 2 2 2 Sodium:solute symporter family SSF PF00474.17 KFM81286.1 - 5.5e-48 163.8 27.7 7.5e-48 163.4 27.7 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Consortin_C PF15281.6 KFM81286.1 - 2 8.4 4.0 4.6 7.3 4.0 1.6 1 0 0 1 1 1 0 Consortin C-terminus SSF PF00474.17 KFM81287.1 - 2.3e-45 155.2 29.9 3.2e-45 154.7 29.9 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Prokineticin PF06607.11 KFM81287.1 - 0.028 14.8 0.2 0.081 13.2 0.2 1.8 1 0 0 1 1 1 0 Prokineticin SurE PF01975.17 KFM81287.1 - 0.16 11.7 0.3 0.33 10.7 0.3 1.5 1 0 0 1 1 1 0 Survival protein SurE Kunitz_BPTI PF00014.23 KFM81288.1 - 1.4e-36 124.4 23.7 2.4e-18 66.1 9.9 2.2 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain PAS_11 PF14598.6 KFM81289.1 - 1e-30 106.1 3.7 1.6e-30 105.5 1.8 2.2 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 KFM81289.1 - 2.7e-05 24.4 0.7 0.00011 22.4 0.2 2.1 2 0 0 2 2 2 1 PAS fold LRR_6 PF13516.6 KFM81291.1 - 7.7e-20 69.2 14.4 0.00019 21.2 2.3 7.7 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 KFM81291.1 - 0.00011 22.6 17.1 0.039 14.4 2.6 5.9 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM81291.1 - 0.0016 18.7 9.2 17 6.4 0.2 7.4 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 KFM81291.1 - 0.094 12.5 14.9 4.7 7.0 0.3 5.6 4 1 0 5 5 5 0 Leucine rich repeat MFS_1 PF07690.16 KFM81292.1 - 0.00048 19.1 0.5 0.00048 19.1 0.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM81292.1 - 0.0041 16.0 0.4 0.0049 15.8 0.0 1.3 2 0 0 2 2 2 1 Sugar (and other) transporter CH PF00307.31 KFM81293.1 - 3.1e-22 78.8 0.0 3.9e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM81293.1 - 0.0057 16.5 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain Ist1 PF03398.14 KFM81294.1 - 3.8e-63 212.3 5.2 4.6e-63 212.0 5.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway LRR_8 PF13855.6 KFM81295.1 - 9.4e-22 76.6 21.3 5.4e-08 32.5 0.1 3.7 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KFM81295.1 - 3.4e-11 43.2 11.7 4.3e-06 27.0 2.0 4.1 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM81295.1 - 1.4e-07 31.2 3.1 0.0035 16.9 0.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KFM81295.1 - 6.6e-05 22.6 3.1 2.6 8.3 0.1 4.9 6 0 0 6 6 6 2 Leucine Rich repeat LRR_5 PF13306.6 KFM81295.1 - 0.00064 19.7 4.2 0.037 14.0 0.2 2.9 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Kdo PF06293.14 KFM81295.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 KFM81295.1 - 0.046 14.2 0.1 0.086 13.4 0.1 1.4 1 0 0 1 1 1 0 PH domain LRR_1 PF00560.33 KFM81295.1 - 0.53 11.0 17.4 4.5 8.2 0.3 6.6 8 0 0 8 8 8 0 Leucine Rich Repeat zf-H2C2_2 PF13465.6 KFM81296.1 - 2e-11 43.8 12.3 3.6e-09 36.6 1.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM81296.1 - 3e-10 40.0 9.3 3.4e-07 30.4 2.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81296.1 - 5.6e-09 36.1 8.2 2.4e-05 24.8 2.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM81296.1 - 3.7e-08 33.0 13.7 1.5e-06 27.8 0.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM81296.1 - 0.0012 19.1 3.9 0.0023 18.2 3.9 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KFM81296.1 - 0.0036 17.1 1.1 0.022 14.5 0.0 2.1 1 1 1 2 2 2 1 GAGA factor zf-met PF12874.7 KFM81296.1 - 0.0065 16.8 4.0 0.019 15.3 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFM81296.1 - 0.017 15.4 5.0 0.32 11.3 5.0 2.1 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFM81296.1 - 0.021 14.8 1.7 0.021 14.8 1.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM81296.1 - 0.023 14.5 1.3 0.023 14.5 1.3 2.4 2 1 0 2 2 2 0 zinc-finger C2H2-type Zn_Tnp_IS1595 PF12760.7 KFM81296.1 - 0.03 14.3 1.4 0.048 13.6 1.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_9 PF16293.5 KFM81296.1 - 0.088 12.7 2.1 7.3 6.5 0.1 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 KFM81296.1 - 0.23 11.5 6.1 0.79 9.8 6.1 2.0 1 1 0 1 1 1 0 BED zinc finger Zn_ribbon_SprT PF17283.2 KFM81296.1 - 0.27 11.2 4.1 0.48 10.4 4.1 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain C1_2 PF03107.16 KFM81296.1 - 0.38 11.1 7.4 3.5 8.0 0.5 2.6 3 0 0 3 3 3 0 C1 domain zf-CHY PF05495.12 KFM81296.1 - 0.48 11.0 7.3 0.51 10.9 1.2 2.2 1 1 1 2 2 2 0 CHY zinc finger Actin_micro PF17003.5 KFM81296.1 - 0.59 9.3 6.7 1.5 7.9 0.4 2.0 1 1 1 2 2 2 0 Putative actin-like family zf-C2HE PF16278.5 KFM81296.1 - 1.3 9.5 5.6 12 6.5 1.2 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-C2H2_12 PF18112.1 KFM81296.1 - 1.7 9.2 7.4 4.6 7.8 1.8 3.4 2 2 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Aldo_ket_red PF00248.21 KFM81297.1 - 6.4e-58 196.3 0.0 8.1e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2666 PF10869.8 KFM81299.1 - 0.042 14.1 0.0 0.052 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Ig_3 PF13927.6 KFM81300.1 - 1.6e-09 38.2 0.2 1.1e-08 35.5 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFM81300.1 - 2.7e-08 34.0 0.0 1.8e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 KFM81300.1 - 3.8e-08 33.3 0.0 4.7e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFM81300.1 - 2.5e-06 27.6 0.0 0.0014 18.7 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM81300.1 - 1.3e-05 25.2 0.0 5.7e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain I-set PF07679.16 KFM81301.1 - 0.00012 22.1 0.0 0.00012 22.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFM81301.1 - 0.00019 21.5 0.0 0.00021 21.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFM81301.1 - 0.0079 16.8 0.0 0.0093 16.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM81301.1 - 0.029 14.6 0.0 0.029 14.6 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain Ig_4 PF16680.5 KFM81301.1 - 0.034 14.4 0.0 0.05 13.9 0.0 1.4 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM81301.1 - 0.094 12.8 0.0 0.094 12.8 0.0 1.1 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 KFM81301.1 - 0.12 12.8 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain COQ9 PF08511.11 KFM81304.1 - 7.6e-26 89.7 0.7 1.1e-25 89.2 0.4 1.4 1 1 0 1 1 1 1 COQ9 SH2 PF00017.24 KFM81305.1 - 2e-12 47.0 0.0 7.3e-12 45.2 0.0 2.0 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFM81305.1 - 1.9e-10 40.9 0.5 3.9e-10 39.9 0.5 1.6 1 0 0 1 1 1 1 SOCS box Pkinase PF00069.25 KFM81306.1 - 2.1e-67 227.3 0.3 2.5e-67 227.0 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM81306.1 - 2.8e-19 69.4 0.1 4e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM81306.1 - 2.6e-08 34.1 0.0 6.1e-07 29.6 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM81306.1 - 0.00047 19.6 0.1 0.00084 18.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFM81306.1 - 0.0049 16.5 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KFM81306.1 - 0.0066 15.3 0.1 0.018 13.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFM81306.1 - 0.0097 15.2 0.2 0.045 13.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFM81306.1 - 0.075 12.6 0.5 1.3 8.5 0.1 2.8 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 RNase_H2_suC PF08615.11 KFM81307.1 - 0.03 14.5 0.3 0.039 14.1 0.3 1.2 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Myosin_tail_1 PF01576.19 KFM81308.1 - 6.3e-82 276.0 178.7 8e-82 275.6 178.7 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 KFM81308.1 - 3.8e-07 30.0 100.0 5.7e-06 26.1 54.6 6.5 1 1 5 6 6 6 3 Intermediate filament protein CEP63 PF17045.5 KFM81308.1 - 5.1e-06 26.6 34.4 5.1e-06 26.6 34.4 7.2 1 1 4 6 6 3 2 Centrosomal protein of 63 kDa Spc7 PF08317.11 KFM81308.1 - 0.00015 20.7 18.9 0.00015 20.7 18.9 8.0 1 1 6 8 8 8 3 Spc7 kinetochore protein CALCOCO1 PF07888.11 KFM81308.1 - 0.00061 18.8 11.0 0.00061 18.8 11.0 5.4 1 1 4 5 5 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_TATA_bd PF12325.8 KFM81308.1 - 0.0045 17.2 10.4 0.0045 17.2 10.4 11.5 2 2 10 12 12 10 2 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 KFM81308.1 - 0.0059 15.9 6.6 0.0059 15.9 6.6 10.1 1 1 9 10 10 9 3 Protein of unknown function (DUF3450) DUF745 PF05335.13 KFM81308.1 - 0.0071 16.1 14.4 0.0071 16.1 14.4 7.6 1 1 6 8 8 8 3 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.9 KFM81308.1 - 0.0074 16.3 23.1 0.0074 16.3 23.1 9.5 1 1 8 9 9 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KFM81308.1 - 0.013 15.6 186.9 0.015 15.4 18.6 9.8 1 1 7 9 9 8 0 TPR/MLP1/MLP2-like protein DUF5340 PF17275.2 KFM81308.1 - 0.016 15.3 4.2 0.016 15.3 4.2 7.1 5 3 2 8 8 8 0 Family of unknown function (DUF5340) SlyX PF04102.12 KFM81308.1 - 0.021 15.5 5.3 0.021 15.5 5.3 14.3 3 2 10 13 13 11 0 SlyX HALZ PF02183.18 KFM81308.1 - 0.021 15.0 4.2 0.021 15.0 4.2 11.8 11 1 1 12 12 9 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KFM81308.1 - 0.027 14.6 1.3 0.027 14.6 1.3 14.2 9 4 6 15 15 15 0 bZIP transcription factor DUF3584 PF12128.8 KFM81308.1 - 0.15 9.5 154.8 0.012 13.1 56.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) MAD PF05557.13 KFM81308.1 - 1.3 7.3 173.2 23 3.2 51.7 5.2 1 1 2 3 3 3 0 Mitotic checkpoint protein Rab5-bind PF09311.11 KFM81309.1 - 0.0001 21.8 11.7 0.0001 21.8 11.7 1.9 2 0 0 2 2 2 1 Rabaptin-like protein TolA_bind_tri PF16331.5 KFM81309.1 - 0.0012 18.8 10.8 0.066 13.3 0.3 3.0 1 1 1 2 2 2 1 TolA binding protein trimerisation Metal_resist PF13801.6 KFM81309.1 - 0.0025 18.0 1.3 0.017 15.3 0.4 2.3 1 1 1 2 2 2 1 Heavy-metal resistance TPR_MLP1_2 PF07926.12 KFM81309.1 - 0.0028 17.7 8.7 0.0028 17.7 8.7 3.2 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 KFM81309.1 - 0.003 17.2 11.1 0.003 17.2 11.1 2.2 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain ATG16 PF08614.11 KFM81309.1 - 0.016 15.5 11.4 0.016 15.5 11.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 KFM81309.1 - 0.064 10.8 22.7 0.16 9.5 6.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NAS PF03059.16 KFM81309.1 - 0.12 11.7 0.5 0.19 11.1 0.1 1.4 2 0 0 2 2 1 0 Nicotianamine synthase protein Golgin_A5 PF09787.9 KFM81309.1 - 0.17 11.3 18.8 0.016 14.7 10.4 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Zw10 PF06248.13 KFM81309.1 - 0.22 10.1 8.5 0.65 8.5 8.5 1.8 1 1 0 1 1 1 0 Centromere/kinetochore Zw10 Baculo_PEP_C PF04513.12 KFM81309.1 - 0.24 11.5 6.1 0.35 10.9 1.6 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 KFM81309.1 - 0.28 10.5 13.9 0.78 9.0 13.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 KFM81309.1 - 0.31 11.4 7.7 3.6 8.0 0.3 2.9 2 0 0 2 2 2 0 Tup N-terminal FAM184 PF15665.5 KFM81309.1 - 0.41 10.4 20.5 0.37 10.6 13.8 2.7 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B Fib_alpha PF08702.10 KFM81309.1 - 0.48 10.6 19.6 0.081 13.1 6.8 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CHASE3 PF05227.13 KFM81309.1 - 0.48 10.3 12.2 1.4 8.8 7.8 2.9 2 1 0 2 2 2 0 CHASE3 domain DASH_Hsk3 PF08227.11 KFM81309.1 - 0.49 10.8 4.5 2.8 8.4 0.3 3.3 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like DUF948 PF06103.11 KFM81309.1 - 0.5 10.6 2.0 27 5.1 0.2 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ApoO PF09769.9 KFM81309.1 - 0.53 10.3 2.5 2.1 8.3 0.6 2.6 1 1 1 2 2 2 0 Apolipoprotein O DUF745 PF05335.13 KFM81309.1 - 0.86 9.3 15.1 0.066 12.9 10.4 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF745) Spc7 PF08317.11 KFM81309.1 - 1.1 8.1 18.4 0.0084 15.0 8.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4472 PF14739.6 KFM81309.1 - 1.1 10.0 14.3 0.12 13.1 5.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) Laminin_II PF06009.12 KFM81309.1 - 1.1 9.2 14.9 0.066 13.2 3.4 3.0 3 0 0 3 3 3 0 Laminin Domain II HALZ PF02183.18 KFM81309.1 - 1.3 9.3 5.7 25 5.2 1.4 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1640 PF07798.11 KFM81309.1 - 1.5 8.8 20.6 5 7.1 6.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF4618 PF15397.6 KFM81309.1 - 1.7 8.0 17.3 0.15 11.5 10.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) YlqD PF11068.8 KFM81309.1 - 2.2 8.6 18.3 0.32 11.4 7.5 3.0 2 1 1 3 3 3 0 YlqD protein DASH_Dam1 PF08653.10 KFM81309.1 - 2.6 7.9 4.0 15 5.5 0.8 3.3 2 1 1 3 3 3 0 DASH complex subunit Dam1 CorA PF01544.18 KFM81309.1 - 2.7 7.2 11.5 0.18 11.1 5.8 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein MbeD_MobD PF04899.12 KFM81309.1 - 2.8 8.1 9.9 5.9 7.1 2.7 3.2 1 1 2 3 3 3 0 MbeD/MobD like EzrA PF06160.12 KFM81309.1 - 3.2 5.8 20.2 0.015 13.5 10.6 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA IFT57 PF10498.9 KFM81309.1 - 3.4 6.5 19.4 14 4.5 19.3 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Phage_Mu_Gam PF07352.12 KFM81309.1 - 4.5 7.2 13.8 6.8 6.6 0.5 3.3 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein Filament PF00038.21 KFM81309.1 - 5.5 6.5 22.1 0.084 12.4 12.2 2.7 3 1 0 3 3 2 0 Intermediate filament protein bZIP_1 PF00170.21 KFM81309.1 - 6.3 7.0 18.5 0.95 9.6 0.4 3.5 3 1 1 4 4 3 0 bZIP transcription factor BMFP PF04380.13 KFM81309.1 - 6.4 7.3 8.1 13 6.3 0.1 3.9 3 1 1 4 4 4 0 Membrane fusogenic activity DUF4201 PF13870.6 KFM81309.1 - 7.2 6.3 20.0 0.083 12.6 6.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 KFM81309.1 - 9.1 6.3 15.0 1.7 8.7 1.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sulfatase PF00884.23 KFM81310.1 - 3e-37 128.7 0.1 3.5e-37 128.5 0.1 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFM81310.1 - 0.0014 18.3 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Ig_3 PF13927.6 KFM81311.1 - 5.9e-12 46.0 0.1 1.1e-11 45.2 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM81311.1 - 2e-10 40.6 0.0 3.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFM81311.1 - 2.1e-10 40.6 0.0 2.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM81311.1 - 8.6e-08 32.4 0.1 1.3e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM81311.1 - 3.1e-07 30.6 0.1 1.1e-06 28.8 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Herpes_gp2 PF05955.11 KFM81311.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 C2-set_2 PF08205.12 KFM81311.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM81311.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin C1-set domain V-set_CD47 PF08204.11 KFM81311.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.6 1 1 0 1 1 1 0 CD47 immunoglobulin-like domain NAD_binding_10 PF13460.6 KFM81312.1 - 8.9e-35 120.2 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFM81312.1 - 1.2e-11 44.6 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFM81312.1 - 1.6e-09 37.6 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM81312.1 - 2.4e-06 26.8 0.7 4.6e-06 25.8 0.7 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PALP PF00291.25 KFM81312.1 - 0.0024 17.4 0.1 0.0032 16.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme adh_short PF00106.25 KFM81312.1 - 0.0043 16.5 0.3 0.0081 15.6 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KFM81312.1 - 0.0054 16.2 0.2 0.024 14.0 0.2 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFM81312.1 - 0.013 14.6 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain RWD PF05773.22 KFM81313.1 - 2.9e-18 66.2 2.0 2.9e-18 66.2 2.0 2.5 2 0 0 2 2 2 1 RWD domain zf-RING_2 PF13639.6 KFM81313.1 - 2.1e-08 34.3 1.8 4.7e-08 33.2 1.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFM81313.1 - 2.5e-06 27.1 5.1 6.2e-06 25.9 5.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KFM81313.1 - 1.4e-05 25.0 3.6 3.3e-05 23.7 3.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFM81313.1 - 0.00027 20.8 3.4 0.00072 19.4 3.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM81313.1 - 0.00073 19.8 3.1 0.0031 17.8 3.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM81313.1 - 0.0025 17.8 2.1 0.0071 16.4 2.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFM81313.1 - 0.0034 17.2 1.0 0.0034 17.2 1.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFM81313.1 - 0.028 14.5 2.1 0.14 12.2 2.1 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KFM81313.1 - 0.15 12.3 1.4 0.54 10.5 1.4 2.1 1 0 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 KFM81313.1 - 0.32 11.1 1.4 0.9 9.7 1.4 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 KFM81313.1 - 0.38 10.7 2.3 0.95 9.4 2.3 1.8 1 0 0 1 1 1 0 PHD-finger cEGF PF12662.7 KFM81314.1 - 5.8e-05 22.9 5.2 0.12 12.3 0.1 2.8 2 0 0 2 2 2 2 Complement Clr-like EGF-like hEGF PF12661.7 KFM81314.1 - 0.00028 21.4 12.3 0.12 13.1 1.7 3.0 2 1 0 2 2 2 2 Human growth factor-like EGF EGF_CA PF07645.15 KFM81314.1 - 0.018 15.2 17.0 0.79 10.0 1.8 3.4 2 2 0 2 2 2 0 Calcium-binding EGF domain EGF PF00008.27 KFM81314.1 - 0.022 15.1 13.7 0.29 11.5 3.2 2.7 2 0 0 2 2 2 0 EGF-like domain FXa_inhibition PF14670.6 KFM81314.1 - 0.03 14.6 8.6 1.1 9.6 1.5 2.6 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site DDE_Tnp_IS1595 PF12762.7 KFM81315.1 - 1.4e-18 67.3 0.0 1.7e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain zf-C2H2 PF00096.26 KFM81320.1 - 2.3e-16 59.2 33.0 2.1e-05 24.7 4.7 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM81320.1 - 5.5e-15 55.0 31.4 3.7e-06 27.1 0.7 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM81320.1 - 1.7e-12 47.3 14.1 0.00013 22.1 0.3 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFM81320.1 - 4.2e-11 42.7 29.9 0.00013 22.5 3.3 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFM81320.1 - 2.1e-07 31.1 22.3 0.00024 21.4 0.6 3.9 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFM81320.1 - 9.9e-05 22.6 20.6 0.09 13.1 6.7 3.2 1 1 2 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding Endonuclease_7 PF02945.15 KFM81320.1 - 0.0028 17.5 5.6 0.0028 17.5 5.6 2.1 1 1 1 2 2 2 1 Recombination endonuclease VII zf-C2H2_6 PF13912.6 KFM81320.1 - 0.0036 17.3 28.4 0.038 14.0 2.1 4.4 4 1 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM81320.1 - 0.032 14.0 0.2 0.032 14.0 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-BED PF02892.15 KFM81320.1 - 0.05 13.6 19.4 1.3 9.1 4.4 3.5 1 1 2 3 3 3 0 BED zinc finger GAGA PF09237.11 KFM81320.1 - 0.11 12.3 9.6 1.7 8.5 0.2 3.7 1 1 3 4 4 4 0 GAGA factor Prok-RING_1 PF14446.6 KFM81320.1 - 0.15 12.0 6.9 12 5.9 0.1 3.8 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 KFM81320.1 - 0.2 11.3 15.6 1.7 8.3 0.7 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 KFM81320.1 - 0.2 11.7 9.7 0.78 9.8 0.5 3.0 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-met2 PF12907.7 KFM81320.1 - 0.22 11.7 9.7 9.3 6.5 0.4 3.6 3 0 0 3 3 3 0 Zinc-binding zinc_ribbon_15 PF17032.5 KFM81320.1 - 0.24 12.2 6.7 1.5 9.6 3.7 2.6 1 1 1 2 2 2 0 zinc-ribbon family zf_ZIC PF18366.1 KFM81320.1 - 0.36 11.0 12.6 0.9 9.7 1.0 3.3 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_2 PF12756.7 KFM81320.1 - 0.54 10.6 17.0 4 7.8 1.0 3.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.6 KFM81320.1 - 0.89 9.5 7.4 1.8 8.5 3.2 2.7 2 1 0 2 2 2 0 Probable zinc-ribbon domain Zn_ribbon_recom PF13408.6 KFM81320.1 - 1.7 9.2 6.9 24 5.6 0.4 3.0 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain Zn-C2H2_12 PF18112.1 KFM81320.1 - 2.2 8.8 18.7 1.2 9.6 0.8 4.4 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 KFM81320.1 - 3.3 7.6 10.5 28 4.6 0.2 3.8 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) UBZ_FAAP20 PF15750.5 KFM81320.1 - 3.4 7.7 9.2 23 5.0 0.2 4.0 4 0 0 4 4 4 0 Ubiquitin-binding zinc-finger DUF2225 PF09986.9 KFM81320.1 - 3.9 7.1 7.7 4.2 7.0 0.6 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-MYST PF17772.1 KFM81320.1 - 4.1 7.1 14.7 7.4 6.3 0.1 3.9 2 2 2 4 4 4 0 MYST family zinc finger domain zf-XS PF03470.14 KFM81320.1 - 4.7 7.6 9.0 0.35 11.2 0.9 2.6 3 0 0 3 3 2 0 XS zinc finger domain LIM PF00412.22 KFM81320.1 - 5.7 7.3 14.1 3.2 8.1 4.7 2.7 2 1 1 3 3 2 0 LIM domain Kazal_1 PF00050.21 KFM81320.1 - 6.6 6.8 8.4 26 4.9 0.6 3.5 4 0 0 4 4 4 0 Kazal-type serine protease inhibitor domain zf-TRAF PF02176.18 KFM81320.1 - 6.6 7.5 17.0 0.096 13.4 6.2 2.5 2 1 1 3 3 3 0 TRAF-type zinc finger DUF2256 PF10013.9 KFM81320.1 - 8.1 6.7 12.6 12 6.1 0.4 3.5 4 0 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.16 KFM81320.1 - 8.4 6.4 16.3 9 6.3 0.6 3.9 4 0 0 4 4 4 0 HIT zinc finger Hamartin PF04388.12 KFM81322.1 - 2.5e-137 459.6 10.6 5.6e-137 458.4 10.6 1.5 1 1 0 1 1 1 1 Hamartin protein bZIP_1 PF00170.21 KFM81322.1 - 0.27 11.4 7.2 0.91 9.7 7.2 1.9 1 0 0 1 1 1 0 bZIP transcription factor Uds1 PF15456.6 KFM81323.1 - 0.012 15.7 6.7 0.026 14.7 6.7 1.6 1 0 0 1 1 1 0 Up-regulated During Septation Phasin PF05597.11 KFM81323.1 - 0.021 14.8 3.2 0.043 13.8 3.0 1.6 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF501 PF04417.12 KFM81323.1 - 0.034 14.0 4.1 0.036 13.9 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF501) DUF5408 PF17402.2 KFM81323.1 - 0.045 13.6 0.9 0.13 12.2 0.9 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5408) FCH PF00611.23 KFM81323.1 - 0.086 13.1 5.1 0.14 12.4 2.3 2.5 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Fez1 PF06818.15 KFM81323.1 - 0.13 12.7 8.6 0.17 12.3 8.6 1.2 1 0 0 1 1 1 0 Fez1 NAD_binding_5 PF07994.12 KFM81323.1 - 0.18 11.1 3.7 0.23 10.8 3.7 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Phage_TAC_4 PF08748.11 KFM81323.1 - 0.29 11.4 4.1 0.12 12.7 1.3 1.7 2 0 0 2 2 2 0 Phage tail assembly chaperone bZIP_1 PF00170.21 KFM81323.1 - 0.3 11.2 12.2 1.4 9.1 1.3 3.4 3 0 0 3 3 3 0 bZIP transcription factor kleA_kleC PF17383.2 KFM81323.1 - 0.3 11.4 4.1 9 6.7 0.3 2.5 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A Spc7 PF08317.11 KFM81323.1 - 0.98 8.2 16.6 2.9 6.7 16.5 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KFM81323.1 - 1.4 9.0 14.6 2.1 8.4 14.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1515 PF07439.11 KFM81323.1 - 1.8 8.6 5.3 14 5.7 5.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Pox_A_type_inc PF04508.12 KFM81323.1 - 2.2 8.3 0.0 2.2 8.3 0.0 4.7 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat SlyX PF04102.12 KFM81323.1 - 3.4 8.3 14.0 1.7 9.3 0.7 3.4 3 1 1 4 4 3 0 SlyX XhlA PF10779.9 KFM81323.1 - 6.7 7.0 9.2 19 5.5 0.6 2.9 2 1 0 2 2 2 0 Haemolysin XhlA DUF4665 PF15679.5 KFM81323.1 - 7.1 7.3 12.2 2.3 8.9 1.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) NPDC1 PF06809.11 KFM81324.1 - 9.8e-36 123.5 0.1 1.3e-35 123.1 0.1 1.1 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) Sarcoglycan_2 PF05510.13 KFM81324.1 - 0.15 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Syndecan PF01034.20 KFM81324.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain SAM_decarbox PF01536.16 KFM81325.1 - 1.2e-43 149.5 0.7 1.3e-43 149.3 0.7 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Crust_neurohorm PF01147.17 KFM81325.1 - 0.048 13.5 0.7 0.084 12.7 0.7 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family SAM_decarbox PF01536.16 KFM81326.1 - 2e-65 221.2 0.1 2.4e-65 220.9 0.1 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase V_ATPase_I PF01496.19 KFM81327.1 - 0 1072.9 18.7 5e-256 851.7 2.5 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family Phage_HK97_TLTM PF06120.11 KFM81327.1 - 0.058 12.6 2.1 0.12 11.6 2.1 1.4 1 0 0 1 1 1 0 Tail length tape measure protein APG6_N PF17675.1 KFM81327.1 - 0.15 12.6 5.9 0.06 13.9 3.1 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 KFM81327.1 - 0.18 12.5 2.9 13 6.5 0.1 3.5 4 0 0 4 4 4 0 Occludin homology domain Epsilon_antitox PF08998.11 KFM81327.1 - 0.21 11.9 1.7 0.63 10.3 0.3 2.3 2 0 0 2 2 2 0 Bacterial epsilon antitoxin DHR10 PF18595.1 KFM81327.1 - 0.71 10.0 6.2 7 6.7 0.7 3.2 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain LRR_9 PF14580.6 KFM81328.1 - 3.3e-15 56.0 0.6 8.6e-15 54.7 0.6 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFM81328.1 - 8.6e-15 54.6 14.4 1.8e-08 34.5 2.5 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM81328.1 - 7.2e-10 38.5 23.7 1.2e-05 25.0 1.9 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KFM81328.1 - 4.3e-08 32.6 2.2 0.24 11.6 0.0 3.9 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 KFM81328.1 - 8.8e-05 22.5 12.2 0.39 11.5 0.1 5.1 4 1 0 4 4 4 3 Leucine Rich Repeat SDA1 PF05285.12 KFM81328.1 - 4.4 6.6 22.1 5.5 6.3 22.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KFM81328.1 - 6.7 4.9 15.1 7.1 4.8 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyoxalase_4 PF13669.6 KFM81329.1 - 1.3e-16 60.8 0.0 1.7e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KFM81329.1 - 3.6e-08 33.6 0.0 4.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFM81329.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain PHR PF08005.12 KFM81331.1 - 2.6e-51 174.3 0.7 5.3e-51 173.3 0.2 1.8 2 0 0 2 2 2 1 PHR domain BTB PF00651.31 KFM81331.1 - 6.6e-28 97.2 0.1 3.2e-26 91.7 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM81331.1 - 7.1e-10 38.9 0.8 8.7e-09 35.4 0.2 2.6 1 1 1 2 2 2 1 BTB And C-terminal Kelch DUF4082 PF13313.6 KFM81331.1 - 0.044 13.8 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Pkinase PF00069.25 KFM81334.1 - 3.3e-08 33.2 0.0 5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LEDGF PF11467.8 KFM81334.1 - 0.029 14.0 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) WD40 PF00400.32 KFM81335.1 - 1.1e-32 111.5 12.1 1.3e-07 32.1 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM81335.1 - 2e-13 50.4 0.6 0.0056 17.0 0.0 4.1 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM81335.1 - 7.4e-06 26.0 2.6 0.16 11.8 0.3 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KFM81335.1 - 0.0011 18.6 0.1 0.0078 15.8 0.0 2.2 2 1 1 3 3 3 1 PQQ-like domain SUKH_6 PF14568.6 KFM81335.1 - 0.15 12.5 0.3 24 5.4 0.1 2.4 2 1 0 2 2 2 0 SMI1-KNR4 cell-wall MIG-14_Wnt-bd PF06664.12 KFM81337.1 - 2.8e-10 39.9 4.1 3e-10 39.8 4.1 1.0 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion MRG PF05712.13 KFM81339.1 - 8.2e-39 133.0 0.2 1.6e-38 132.0 0.2 1.5 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KFM81339.1 - 2.8e-15 55.9 0.2 2.8e-15 55.9 0.2 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain SBP_bac_3 PF00497.20 KFM81340.1 - 1.1e-08 34.8 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 KFM81340.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel Lig_chan PF00060.26 KFM81341.1 - 2.3e-12 47.0 0.0 2.4e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 Ligand-gated ion channel NVEALA PF14055.6 KFM81341.1 - 0.042 13.8 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 NVEALA protein RXT2_N PF08595.11 KFM81341.1 - 0.17 11.9 0.0 0.19 11.8 0.0 1.0 1 0 0 1 1 1 0 RXT2-like, N-terminal Lig_chan-Glu_bd PF10613.9 KFM81342.1 - 1.2e-42 144.8 0.0 1.5e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM81342.1 - 9e-14 51.4 0.0 2e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFM81343.1 - 8.1e-37 127.1 0.2 9.3e-37 126.9 0.2 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region GP67 PF17634.2 KFM81343.1 - 0.006 17.0 0.1 0.016 15.6 0.1 1.6 1 0 0 1 1 1 1 Gene product 67 POP1 PF06978.11 KFM81343.1 - 0.06 13.3 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 BH4 PF02180.17 KFM81343.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Bcl-2 homology region 4 Lig_chan PF00060.26 KFM81344.1 - 6.4e-50 168.9 0.3 1.1e-49 168.2 0.3 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 KFM81344.1 - 1.6e-45 155.8 0.3 2.2e-45 155.3 0.3 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFM81344.1 - 5.7e-42 142.5 0.1 1.2e-41 141.5 0.1 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM81344.1 - 2.9e-25 89.0 0.0 1.1e-24 87.2 0.0 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 KFM81344.1 - 3.9 7.5 8.0 0.2 11.7 1.7 2.1 2 0 0 2 2 2 0 Ion channel Bestrophin PF01062.21 KFM81345.1 - 7.3e-67 225.8 4.3 8.2e-67 225.7 4.3 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 KFM81346.1 - 4.6e-12 45.9 0.3 6e-12 45.6 0.3 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel I-EGF_1 PF18372.1 KFM81349.1 - 1.7e-09 37.6 41.7 2.1e-05 24.5 16.1 3.6 3 1 0 3 3 3 2 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFM81349.1 - 1.8e-06 28.2 34.7 9.1e-05 22.8 5.7 3.3 3 0 0 3 3 3 2 EGF-like domain Integrin_beta PF00362.18 KFM81351.1 - 3.3e-08 33.5 0.3 3.8e-08 33.3 0.3 1.1 1 0 0 1 1 1 1 Integrin beta chain VWA domain DUF4232 PF14016.6 KFM81351.1 - 0.012 15.7 0.0 0.013 15.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) Mitoc_L55 PF09776.9 KFM81353.1 - 0.11 12.3 1.6 0.26 11.0 1.6 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Nebulin PF00880.18 KFM81353.1 - 0.16 11.9 3.3 0.35 10.8 3.3 1.6 1 0 0 1 1 1 0 Nebulin repeat CAP160 PF07918.11 KFM81354.1 - 4.2 7.2 11.5 5.1 6.9 2.1 3.1 3 0 0 3 3 3 0 CAP160 repeat BTB PF00651.31 KFM81356.1 - 2.9e-08 33.9 0.0 3.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Vps5 PF09325.10 KFM81356.1 - 0.056 13.0 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Vps5 C terminal like DUF1053 PF06327.14 KFM81357.1 - 0.00012 22.6 0.0 0.00015 22.2 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) Guanylate_cyc PF00211.20 KFM81358.1 - 1.8e-54 184.2 0.1 2.4e-54 183.8 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ribosomal_L21p PF00829.21 KFM81359.1 - 4.7e-14 52.5 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ig_3 PF13927.6 KFM81360.1 - 2.4e-09 37.7 0.0 7.8e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM81360.1 - 2.3e-08 34.3 0.2 0.0049 17.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM81360.1 - 4.7e-05 23.5 0.0 0.034 14.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFM81360.1 - 0.00012 22.1 0.1 0.00033 20.7 0.0 1.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFM81360.1 - 0.002 18.2 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFM81360.1 - 0.008 16.3 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM81360.1 - 0.18 12.1 0.5 2.7 8.3 0.0 2.6 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Rubella_E1 PF05748.11 KFM81360.1 - 0.21 10.4 0.8 0.26 10.1 0.0 1.5 2 0 0 2 2 2 0 Rubella membrane glycoprotein E1 Pkinase PF00069.25 KFM81362.1 - 3.3e-48 164.3 0.1 7.6e-48 163.2 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM81362.1 - 4.4e-22 78.6 0.0 1.2e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFM81362.1 - 0.0036 16.3 0.1 0.0063 15.5 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase CS PF04969.16 KFM81363.1 - 3.6e-12 47.1 0.1 7.6e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 CS domain S1 PF00575.23 KFM81364.1 - 5.3e-06 26.7 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain RNase_PH_C PF03725.15 KFM81364.1 - 1.5e-05 24.9 0.0 2.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_1 PF00013.29 KFM81364.1 - 3e-05 23.8 0.0 6.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 KH domain RNase_PH PF01138.21 KFM81365.1 - 9.2e-15 55.3 0.1 3.8e-07 30.7 0.0 2.9 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFM81365.1 - 1e-13 51.1 0.2 2.6e-13 49.8 0.2 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PNPase PF03726.14 KFM81365.1 - 2.5e-11 43.9 0.1 2.5e-11 43.9 0.1 2.4 3 0 0 3 3 3 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain Diphthami_syn_2 PF01902.17 KFM81366.1 - 1.2e-43 149.1 0.2 2.2e-43 148.3 0.2 1.3 1 1 0 1 1 1 1 Diphthamide synthase PAN_1 PF00024.26 KFM81368.1 - 7.3e-19 67.5 12.3 6.7e-12 45.2 0.5 3.3 3 0 0 3 3 3 2 PAN domain PAN_4 PF14295.6 KFM81368.1 - 9.3e-07 28.7 9.3 0.097 12.6 0.5 3.5 3 0 0 3 3 3 3 PAN domain Carb_bind PF10645.9 KFM81368.1 - 0.13 12.5 7.0 0.44 10.8 0.1 3.2 3 0 0 3 3 3 0 Carbohydrate binding PAN_2 PF08276.11 KFM81368.1 - 0.4 10.8 9.2 1.9 8.6 0.8 3.3 3 0 0 3 3 3 0 PAN-like domain Mito_fiss_reg PF05308.11 KFM81368.1 - 1.3 9.1 5.9 2.1 8.4 5.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KFM81368.1 - 1.9 7.9 6.4 2.7 7.4 6.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PAN_1 PF00024.26 KFM81369.1 - 1.3e-16 60.3 9.6 1.9e-12 46.9 1.9 2.8 3 0 0 3 3 3 2 PAN domain PAN_4 PF14295.6 KFM81369.1 - 1.5e-06 28.0 4.0 0.0051 16.7 0.1 2.4 2 0 0 2 2 2 2 PAN domain DUF725 PF05267.12 KFM81369.1 - 0.029 14.4 2.3 6.5 6.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF725) PAN_2 PF08276.11 KFM81369.1 - 0.036 14.2 5.3 0.49 10.6 0.5 2.5 2 0 0 2 2 2 0 PAN-like domain PAN_1 PF00024.26 KFM81370.1 - 1.2e-26 92.4 17.6 2.7e-14 52.9 2.3 3.2 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 KFM81370.1 - 0.098 12.6 18.7 0.34 10.8 2.6 3.9 3 1 1 4 4 4 0 PAN domain MBT PF02820.18 KFM81371.1 - 0.18 12.2 0.0 0.21 12.0 0.0 1.3 1 1 0 1 1 1 0 mbt repeat fn3 PF00041.21 KFM81372.1 - 0 1335.0 48.9 6.9e-19 68.0 0.0 28.1 28 0 0 28 28 28 27 Fibronectin type III domain I-set PF07679.16 KFM81372.1 - 0 996.7 7.0 1.6e-22 79.3 0.0 21.6 20 0 0 20 20 20 18 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM81372.1 - 1.6e-177 576.6 9.4 3.8e-13 49.8 0.0 20.4 19 0 0 19 19 19 17 Immunoglobulin domain Ig_2 PF13895.6 KFM81372.1 - 2.2e-85 281.0 22.4 2.3e-08 34.2 0.1 19.2 20 0 0 20 20 18 13 Immunoglobulin domain ig PF00047.25 KFM81372.1 - 4.6e-79 260.7 18.1 2.8e-09 37.0 0.0 16.8 16 0 0 16 16 16 11 Immunoglobulin domain Pkinase PF00069.25 KFM81372.1 - 1.2e-68 231.4 0.0 1.8e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pur_ac_phosph_N PF16656.5 KFM81372.1 - 3.9e-42 142.7 32.9 0.04 14.5 0.0 26.9 26 3 0 26 26 25 6 Purple acid Phosphatase, N-terminal domain Pkinase_Tyr PF07714.17 KFM81372.1 - 2.9e-32 112.0 0.0 4.9e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.12 KFM81372.1 - 8.1e-25 86.7 1.4 0.05 13.7 0.0 13.5 14 0 0 14 14 14 5 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFM81372.1 - 3.8e-23 81.7 21.4 0.18 12.0 0.1 18.7 17 5 0 17 17 16 4 Immunoglobulin V-set domain Tissue_fac PF01108.17 KFM81372.1 - 2.7e-22 78.7 2.2 0.096 12.5 0.0 16.6 20 0 0 20 20 16 2 Tissue factor Receptor_2B4 PF11465.8 KFM81372.1 - 1.3e-12 47.8 2.9 2.7 8.2 0.0 11.4 13 0 0 13 13 12 2 Natural killer cell receptor 2B4 DUF2369 PF10179.9 KFM81372.1 - 1.5e-12 47.8 0.0 4.1 7.9 0.0 13.7 18 0 0 18 18 15 1 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 KFM81372.1 - 4.6e-12 45.9 0.0 39 4.5 0.0 12.4 12 1 0 12 12 12 0 Fibronectin type III domain PhoD_N PF16655.5 KFM81372.1 - 1.2e-09 38.6 1.5 40 4.8 0.0 11.6 14 0 0 14 14 11 0 PhoD-like phosphatase, N-terminal domain C1-set PF07654.15 KFM81372.1 - 2.3e-09 37.5 7.1 0.73 10.3 0.0 7.9 7 0 0 7 7 7 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM81372.1 - 1.3e-07 31.8 5.5 0.18 12.1 0.0 6.0 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM81372.1 - 3.6e-07 30.1 0.8 1.1 9.4 0.0 7.2 8 0 0 8 8 7 1 Izumo-like Immunoglobulin domain bMG6 PF17962.1 KFM81372.1 - 8.1e-06 26.0 4.9 67 3.7 0.0 11.8 16 0 0 16 16 11 0 Bacterial macroglobulin domain 6 Kdo PF06293.14 KFM81372.1 - 1.1e-05 24.9 0.1 2e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF11 PF01345.18 KFM81372.1 - 7.1e-05 23.0 3.2 6.8 7.1 0.0 8.8 11 0 0 11 11 9 1 Domain of unknown function DUF11 Ig_6 PF18452.1 KFM81372.1 - 0.00032 20.2 1.6 2.4 7.8 0.1 5.0 5 0 0 5 5 4 1 Immunoglobulin domain TQ PF18202.1 KFM81372.1 - 0.00039 20.9 0.1 1.1e+02 3.3 0.0 7.5 7 0 0 7 7 7 0 T-Q ester bond containing domain Glyco_hydro_36C PF16874.5 KFM81372.1 - 0.0015 19.0 0.0 93 3.6 0.0 6.6 8 0 0 8 8 6 0 Glycosyl hydrolase family 36 C-terminal domain Arylsulfotran_N PF17425.2 KFM81372.1 - 0.05 13.6 0.0 71 3.5 0.0 5.6 6 0 0 6 6 5 0 Arylsulfotransferase Ig-like domain I-set PF07679.16 KFM81373.1 - 1.6e-131 428.8 40.5 3.4e-18 65.5 2.1 12.0 12 0 0 12 12 11 11 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM81373.1 - 1.3e-90 298.1 5.8 2.2e-09 37.8 0.7 10.8 11 0 0 11 11 11 10 Immunoglobulin domain ig PF00047.25 KFM81373.1 - 1.3e-61 204.7 14.0 1.7e-07 31.3 1.6 10.5 10 0 0 10 10 10 9 Immunoglobulin domain Ig_2 PF13895.6 KFM81373.1 - 3.4e-59 197.1 3.9 6.8e-06 26.3 0.0 10.5 10 0 0 10 10 10 10 Immunoglobulin domain V-set PF07686.17 KFM81373.1 - 7.5e-34 116.2 26.5 0.0089 16.2 0.1 14.5 10 6 0 10 10 10 8 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM81373.1 - 1.4e-13 50.2 0.1 0.016 14.8 0.0 6.9 7 0 0 7 7 7 3 Immunoglobulin domain C1-set PF07654.15 KFM81373.1 - 6.6e-12 45.6 12.0 0.09 13.2 0.0 9.4 8 1 1 9 9 9 2 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFM81373.1 - 1.9e-11 43.8 18.3 0.66 10.1 0.1 10.4 10 1 0 10 10 10 4 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFM81373.1 - 7.2e-09 35.6 6.8 0.93 9.6 0.0 7.8 7 1 1 8 8 8 1 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 KFM81373.1 - 2.1e-08 34.4 0.0 1.7e-07 31.5 0.0 2.7 2 0 0 2 2 1 1 Fibronectin type III domain Receptor_2B4 PF11465.8 KFM81373.1 - 5.8e-08 32.9 9.3 0.08 13.1 0.1 7.5 7 0 0 7 7 7 2 Natural killer cell receptor 2B4 BiPBP_C PF06832.12 KFM81373.1 - 0.0019 18.2 0.0 1.1 9.4 0.0 5.1 6 0 0 6 6 6 1 Penicillin-Binding Protein C-terminus Family Ig_C17orf99 PF17736.1 KFM81373.1 - 0.005 16.8 0.1 9.4 6.3 0.0 5.2 6 1 1 7 7 7 1 C17orf99 Ig domain Marek_A PF02124.15 KFM81373.1 - 0.044 13.6 0.1 2.6 7.8 0.0 3.4 4 0 0 4 4 4 0 Marek's disease glycoprotein A Mem_trans PF03547.18 KFM81373.1 - 0.07 11.5 2.1 0.12 10.8 2.1 1.5 1 0 0 1 1 1 0 Membrane transport protein I-set PF07679.16 KFM81374.1 - 3.2e-35 120.1 0.0 5.8e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM81374.1 - 1e-24 86.9 0.0 1.9e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM81374.1 - 7.8e-15 55.0 0.0 7.9e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM81374.1 - 9.5e-14 51.3 0.0 6.4e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM81374.1 - 2e-06 28.0 0.1 0.019 15.2 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFM81374.1 - 0.0093 16.0 0.0 0.034 14.2 0.0 1.8 2 0 0 2 2 2 1 C17orf99 Ig domain C2-set_2 PF08205.12 KFM81374.1 - 0.021 14.9 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM81374.1 - 0.022 15.1 0.0 8.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C1-set domain I-set PF07679.16 KFM81375.1 - 3.9e-17 62.1 0.0 4.4e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM81375.1 - 1.1e-10 42.0 0.0 1.3e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM81375.1 - 1.8e-06 28.2 0.0 2.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM81375.1 - 6.9e-05 23.0 0.0 8.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFM81375.1 - 0.0001 22.4 0.1 0.003 17.7 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM81375.1 - 0.0041 17.1 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain DTW PF03942.15 KFM81376.1 - 0.039 13.7 0.2 0.039 13.7 0.2 1.0 1 0 0 1 1 1 0 DTW domain PrmC_N PF17827.1 KFM81376.1 - 0.12 12.9 0.0 0.22 12.2 0.0 1.3 1 1 0 1 1 1 0 PrmC N-terminal domain BTB PF00651.31 KFM81377.1 - 2.1e-09 37.6 0.5 2.3e-08 34.2 0.1 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM81377.1 - 1.4e-08 34.7 5.1 2.6e-08 33.9 5.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Cadherin_3 PF16184.5 KFM81378.1 - 5.9e-190 618.7 32.8 1.2e-26 92.9 0.4 9.1 9 0 0 9 9 9 9 Cadherin-like Big_9 PF17963.1 KFM81378.1 - 5.6e-12 46.2 32.0 0.0068 17.1 0.0 9.9 9 4 0 9 9 9 4 Bacterial Ig domain Cadherin_4 PF17803.1 KFM81378.1 - 3.6e-10 40.3 24.9 0.18 12.4 0.1 9.7 8 2 1 9 9 9 5 Bacterial cadherin-like domain Cadherin_3 PF16184.5 KFM81379.1 - 1.9e-45 153.4 4.6 4.5e-27 94.2 0.0 4.9 6 0 0 6 6 6 4 Cadherin-like PHD_2 PF13831.6 KFM81381.1 - 8e-14 50.9 6.0 8e-14 50.9 6.0 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KFM81381.1 - 8.8e-12 44.7 9.5 8.8e-12 44.7 9.5 1.6 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.9 KFM81381.1 - 3e-06 27.7 3.0 3e-06 27.7 3.0 1.7 1 1 1 2 2 2 1 Enhancer of polycomb-like C1_1 PF00130.22 KFM81381.1 - 0.00015 21.6 3.8 0.00015 21.6 3.8 2.2 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 KFM81381.1 - 0.0016 18.7 1.2 0.0024 18.1 1.2 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-PHD-like PF15446.6 KFM81381.1 - 0.047 13.3 6.5 0.092 12.4 6.5 1.5 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RING_9 PF13901.6 KFM81381.1 - 0.38 10.7 8.2 0.11 12.5 5.9 1.4 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RRPl_C4 PF17026.5 KFM81381.1 - 0.45 10.7 6.6 1 9.5 6.6 1.7 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-UDP PF14569.6 KFM81381.1 - 0.96 9.6 8.0 2 8.6 7.4 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger C1_2 PF03107.16 KFM81381.1 - 1.3 9.4 13.3 0.25 11.7 5.2 2.6 2 1 0 2 2 2 0 C1 domain DZR PF12773.7 KFM81381.1 - 9 6.4 13.4 15 5.7 4.5 2.6 2 1 1 3 3 3 0 Double zinc ribbon Peptidase_C1 PF00112.23 KFM81382.1 - 0.15 12.2 0.1 0.17 12.0 0.1 1.1 1 0 0 1 1 1 0 Papain family cysteine protease AnmK PF03702.14 KFM81384.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase UNC45-central PF11701.8 KFM81388.1 - 1.8e-35 122.2 18.5 2.4e-31 108.7 0.7 5.2 4 1 0 4 4 4 3 Myosin-binding striated muscle assembly central TPR_1 PF00515.28 KFM81388.1 - 4.9e-17 61.0 5.0 5.2e-06 26.0 0.4 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM81388.1 - 3.7e-15 54.7 4.9 3.4e-05 23.6 0.2 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat Arm PF00514.23 KFM81388.1 - 3.8e-11 42.6 11.0 0.025 14.6 0.0 9.7 10 0 0 10 10 10 2 Armadillo/beta-catenin-like repeat TPR_11 PF13414.6 KFM81388.1 - 2.4e-08 33.5 0.1 3.2e-05 23.5 0.1 3.1 1 1 1 2 2 2 2 TPR repeat HEAT_2 PF13646.6 KFM81388.1 - 1.5e-07 31.7 7.0 0.0085 16.5 0.0 6.1 5 2 1 6 6 6 1 HEAT repeats TPR_12 PF13424.6 KFM81388.1 - 4e-07 30.2 1.4 2e-06 28.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM81388.1 - 1.4e-06 28.1 2.9 0.012 15.8 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM81388.1 - 8.2e-05 23.0 1.4 0.23 12.0 0.3 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM81388.1 - 8.5e-05 23.1 0.1 4.3 8.4 0.0 4.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM81388.1 - 8.9e-05 22.3 0.3 0.034 14.2 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM81388.1 - 0.0017 18.4 0.1 0.029 14.5 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM81388.1 - 0.0097 16.5 0.6 8.2 7.2 0.2 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat IMPDH PF00478.25 KFM81388.1 - 0.028 13.4 1.3 4.3 6.2 0.1 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain TPR_17 PF13431.6 KFM81388.1 - 0.074 13.5 0.2 12 6.5 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KFM81388.1 - 0.12 12.4 7.0 0.42 10.7 2.0 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 KFM81388.1 - 0.16 11.7 3.8 5.2 6.7 3.8 2.7 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Atx10homo_assoc PF09759.9 KFM81388.1 - 0.19 11.8 4.0 23 5.1 0.1 4.6 4 0 0 4 4 3 0 Spinocerebellar ataxia type 10 protein domain DDE_Tnp_IS1595 PF12762.7 KFM81389.1 - 3.6e-06 27.1 0.0 4.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Myotub-related PF06602.14 KFM81390.1 - 3.7e-140 466.9 0.0 4.6e-140 466.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 KFM81390.1 - 2e-11 43.9 9.7 4.2e-11 42.8 9.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger DSPc PF00782.20 KFM81390.1 - 0.00019 21.3 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM81390.1 - 0.0011 18.7 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM81390.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-RING_5 PF14634.6 KFM81390.1 - 0.33 11.0 9.1 1.6 8.7 9.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Dicer_dimer PF03368.14 KFM81391.1 - 9.9e-30 102.6 0.0 2.1e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KFM81391.1 - 3.3e-16 59.6 0.0 8.6e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM81391.1 - 3.2e-13 49.8 0.0 6.7e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM81391.1 - 2.1e-12 47.4 0.0 7.6e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 KFM81391.1 - 0.034 14.9 0.0 0.45 11.3 0.0 2.6 2 0 0 2 2 2 0 Double-stranded RNA binding motif AAA_19 PF13245.6 KFM81391.1 - 0.079 13.3 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain XPG_I PF00867.18 KFM81393.1 - 3.1e-23 81.9 0.5 2.9e-22 78.8 0.0 2.5 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KFM81393.1 - 1.3e-13 51.3 0.1 3.8e-13 49.8 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain Chromo_2 PF18704.1 KFM81393.1 - 4.5e-06 26.8 1.3 1.2e-05 25.5 1.3 1.8 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 5_3_exonuc PF01367.20 KFM81393.1 - 0.04 14.5 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 KFM81393.1 - 0.094 13.0 0.0 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family Ig_3 PF13927.6 KFM81394.1 - 1.1e-06 29.1 0.1 1.9e-06 28.3 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM81394.1 - 3.8e-06 26.9 0.1 1.4e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM81394.1 - 5.8e-05 23.3 0.0 0.00015 22.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM81394.1 - 0.018 15.2 0.0 0.13 12.4 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 KFM81394.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain E1_dh PF00676.20 KFM81395.1 - 1e-81 274.2 0.0 1.6e-81 273.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KFM81395.1 - 5.7e-70 234.6 0.0 1e-69 233.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFM81395.1 - 1.2e-53 180.8 0.0 2e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KFM81395.1 - 7.8e-20 70.2 0.8 7.8e-20 70.2 0.8 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus HGTP_anticodon PF03129.20 KFM81396.1 - 2.7e-20 72.3 0.0 7.2e-20 70.9 0.0 1.6 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.20 KFM81399.1 - 0.015 15.5 1.1 0.022 14.9 0.1 1.7 2 0 0 2 2 2 0 WHEP-TRS domain RPN1_RPN2_N PF17781.1 KFM81399.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Nfu_N PF08712.11 KFM81400.1 - 2.1e-33 114.2 0.1 4.4e-33 113.2 0.1 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KFM81400.1 - 1.6e-26 92.2 0.1 2.6e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Lipase PF00151.19 KFM81401.1 - 5.4e-89 298.8 0.0 7.2e-89 298.4 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFM81401.1 - 0.00016 22.4 0.1 0.00033 21.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KFM81401.1 - 0.053 13.4 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF2167 PF09935.9 KFM81401.1 - 0.1 11.8 0.1 0.23 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) HPS3_N PF14761.6 KFM81402.1 - 0.032 13.8 0.5 0.041 13.4 0.5 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 UPF0160 PF03690.13 KFM81402.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) RDD PF06271.12 KFM81403.1 - 1.1e-10 41.8 1.9 1.4e-09 38.3 1.9 2.1 1 1 0 1 1 1 1 RDD family MCR_beta_N PF02783.15 KFM81403.1 - 0.096 12.3 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Mesd PF10185.9 KFM81405.1 - 1.8e-44 151.4 1.1 1.9e-44 151.3 1.1 1.0 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor SecD-TM1 PF13721.6 KFM81405.1 - 0.038 14.4 0.0 0.05 14.1 0.0 1.1 1 0 0 1 1 1 0 SecD export protein N-terminal TM region BTB PF00651.31 KFM81407.1 - 5.7e-24 84.5 3.3 1.1e-23 83.6 0.6 2.4 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFM81407.1 - 0.1 12.7 1.5 0.34 11.0 0.0 2.5 3 0 0 3 3 3 0 BTB And C-terminal Kelch Peptidase_M13 PF01431.21 KFM81408.1 - 2.1e-27 96.1 0.0 2.3e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM81409.1 - 0.00029 20.6 0.1 0.00049 19.9 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFM81410.1 - 3.5e-21 75.8 0.0 3.8e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 p450 PF00067.22 KFM81412.1 - 1.4e-78 264.7 0.0 1.7e-78 264.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.10 KFM81412.1 - 0.017 14.5 1.5 0.04 13.3 1.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3310 PF11753.8 KFM81412.1 - 0.034 14.3 0.0 5 7.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknwon function (DUF3310) p450 PF00067.22 KFM81413.1 - 3.6e-86 289.7 0.0 4.5e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP20 PF00011.21 KFM81414.1 - 8.8e-25 86.8 0.3 1.1e-24 86.5 0.3 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFM81414.1 - 2.7e-06 27.4 0.8 4.8e-06 26.6 0.8 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal ArsA_HSP20 PF17886.1 KFM81414.1 - 7.1e-05 22.3 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA RRM_1 PF00076.22 KFM81416.1 - 0.0019 18.0 0.0 0.3 11.0 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G_glu_transpept PF01019.21 KFM81416.1 - 0.29 9.8 3.4 0.42 9.3 2.1 1.7 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase HECT PF00632.25 KFM81417.1 - 2.6e-88 296.5 0.2 3.8e-88 295.9 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FGF PF00167.18 KFM81418.1 - 7.5e-21 74.5 1.3 8.4e-21 74.4 1.3 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFM81418.1 - 0.001 19.3 0.2 0.0012 19.1 0.2 1.1 1 0 0 1 1 1 1 Fascin domain FRG1 PF06229.12 KFM81418.1 - 0.067 12.9 0.0 0.079 12.7 0.0 1.0 1 0 0 1 1 1 0 FRG1-like domain Reticulon PF02453.17 KFM81419.1 - 3.7e-06 27.0 6.9 5.1e-06 26.5 6.9 1.3 1 0 0 1 1 1 1 Reticulon DUF456 PF04306.13 KFM81419.1 - 0.016 15.5 0.5 0.016 15.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF456) HXXEE PF13787.6 KFM81419.1 - 0.042 14.6 7.0 0.1 13.4 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function with HXXEE motif MgtE PF01769.16 KFM81419.1 - 0.16 12.4 5.5 0.18 12.2 0.8 2.2 2 0 0 2 2 2 0 Divalent cation transporter UBA_4 PF14555.6 KFM81420.1 - 4.8e-08 32.7 0.5 7.7e-08 32.0 0.5 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KFM81420.1 - 0.0024 17.5 1.2 0.0029 17.2 0.2 1.7 2 0 0 2 2 2 1 TAP C-terminal domain Nucleoside_tran PF01733.18 KFM81421.1 - 2.3e-52 178.3 16.9 5.1e-50 170.6 16.9 2.4 1 1 0 1 1 1 1 Nucleoside transporter DUF3989 PF13150.6 KFM81421.1 - 5 6.9 4.8 4.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) RAWUL PF16207.5 KFM81423.1 - 0.00012 22.7 0.2 0.00023 21.8 0.2 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like HGTP_anticodon2 PF12745.7 KFM81423.1 - 0.034 13.7 0.4 0.035 13.6 0.4 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF866 PF05907.13 KFM81425.1 - 4e-59 199.0 0.7 4.5e-59 198.8 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LRR_8 PF13855.6 KFM81426.1 - 0.028 14.2 0.2 0.03 14.1 0.2 1.1 1 0 0 1 1 1 0 Leucine rich repeat LRR_8 PF13855.6 KFM81427.1 - 1.8e-20 72.5 27.2 4.8e-07 29.4 5.4 4.4 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFM81427.1 - 3.1e-13 49.7 35.2 1.1e-06 28.9 1.1 5.8 2 1 4 7 7 7 6 Leucine Rich repeats (2 copies) RsmF_methylt_CI PF17126.5 KFM81427.1 - 5.4e-05 23.2 0.4 0.018 15.1 0.0 3.9 2 1 2 5 5 5 1 RsmF rRNA methyltransferase first C-terminal domain LRR_5 PF13306.6 KFM81427.1 - 0.00074 19.5 2.4 0.4 10.7 1.6 2.9 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) DUF3629 PF12302.8 KFM81427.1 - 0.064 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Pkinase_Tyr PF07714.17 KFM81429.1 - 1.9e-44 151.9 0.0 2.5e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM81429.1 - 1e-23 84.0 0.0 1.5e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFM81429.1 - 0.023 14.8 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF3933 PF13069.6 KFM81429.1 - 0.13 12.1 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) Cadherin_C_2 PF16492.5 KFM81429.1 - 0.81 10.5 5.1 2.5 8.9 5.1 1.9 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Hum_adeno_E3A PF05393.11 KFM81429.1 - 7.9 6.5 6.1 32 4.6 0.2 2.3 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein Ig_3 PF13927.6 KFM81430.1 - 0.0031 18.1 0.2 0.0038 17.8 0.2 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM81430.1 - 0.031 14.3 0.0 0.034 14.2 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin I-set domain Cystatin PF00031.21 KFM81433.1 - 1.9e-14 53.7 0.1 2.2e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFM81433.1 - 7.4e-06 26.2 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor CHDCT2 PF08074.11 KFM81434.1 - 2.5e-34 118.9 0.7 3.8e-34 118.3 0.7 1.3 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain DUF1086 PF06461.11 KFM81435.1 - 3.9e-59 198.4 1.2 1.4e-58 196.7 0.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) SNF2_N PF00176.23 KFM81435.1 - 8.5e-58 195.7 0.0 2.8e-57 194.0 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain CHDNT PF08073.12 KFM81435.1 - 1.6e-28 98.4 0.2 4.4e-28 97.0 0.2 1.8 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF1087 PF06465.13 KFM81435.1 - 6.9e-28 96.5 3.2 6.9e-28 96.5 3.2 3.7 3 0 0 3 3 2 1 Domain of Unknown Function (DUF1087) Helicase_C PF00271.31 KFM81435.1 - 2.1e-22 79.5 0.0 5.6e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 KFM81435.1 - 6.8e-22 77.1 24.7 6.9e-11 41.9 6.7 2.6 2 0 0 2 2 2 2 PHD-finger Chromo PF00385.24 KFM81435.1 - 4.8e-14 52.0 18.0 3.4e-12 46.1 0.7 3.8 4 0 0 4 4 2 2 Chromo (CHRromatin Organisation MOdifier) domain CHDCT2 PF08074.11 KFM81435.1 - 4.6e-12 46.4 6.2 4.6e-12 46.4 6.2 2.0 2 0 0 2 2 1 1 CHDCT2 (NUC038) domain ResIII PF04851.15 KFM81435.1 - 2.8e-07 30.7 0.0 2.8e-07 30.7 0.0 3.4 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 KFM81435.1 - 0.001 19.4 0.1 0.0056 17.1 0.1 2.4 1 0 0 1 1 1 1 HMG (high mobility group) box HDA2-3 PF11496.8 KFM81435.1 - 0.0017 17.6 0.0 0.0017 17.6 0.0 3.3 3 1 0 3 3 2 1 Class II histone deacetylase complex subunits 2 and 3 PHD_2 PF13831.6 KFM81435.1 - 0.0076 15.8 12.9 0.072 12.7 4.7 2.8 2 0 0 2 2 2 2 PHD-finger DEAD PF00270.29 KFM81435.1 - 0.03 14.1 0.0 0.26 11.0 0.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase TonB_2 PF13103.6 KFM81435.1 - 0.06 13.6 0.4 0.25 11.6 0.4 2.1 1 0 0 1 1 1 0 TonB C terminal AAA_22 PF13401.6 KFM81435.1 - 0.12 12.7 0.0 0.56 10.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain zf-HC5HC2H_2 PF13832.6 KFM81435.1 - 0.3 11.3 14.5 1.1 9.4 0.6 3.1 3 0 0 3 3 3 0 PHD-zinc-finger like domain zf-RanBP PF00641.18 KFM81435.1 - 3.3 7.1 9.0 8 5.9 1.7 2.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Ribosomal_L37ae PF01780.19 KFM81436.1 - 7.8e-42 141.3 13.6 8.7e-42 141.1 13.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family CarbpepA_inh PF02977.15 KFM81436.1 - 0.00016 21.4 1.2 0.00016 21.4 1.2 1.8 1 1 1 2 2 2 1 Carboxypeptidase A inhibitor MRNIP PF15749.5 KFM81436.1 - 0.011 16.4 6.9 0.43 11.3 3.3 2.4 1 1 1 2 2 2 0 MRN-interacting protein Zn_Tnp_IS1595 PF12760.7 KFM81436.1 - 0.018 15.0 3.8 0.031 14.3 3.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF1451 PF07295.11 KFM81436.1 - 0.085 12.9 3.0 0.13 12.3 3.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-BED PF02892.15 KFM81436.1 - 0.17 11.9 6.3 2.6 8.1 0.9 2.2 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.16 KFM81436.1 - 0.26 11.6 3.8 3.7 7.9 3.8 2.1 1 1 0 1 1 1 0 C1 domain Arm PF00514.23 KFM81437.1 - 7.9e-15 54.3 1.6 0.0012 18.8 0.1 7.0 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFM81437.1 - 2.9e-06 27.6 0.0 0.0015 18.9 0.0 4.2 3 1 2 5 5 5 1 HEAT repeats Helicase_C_4 PF13871.6 KFM81437.1 - 0.013 15.2 0.2 0.028 14.1 0.2 1.5 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue RTP1_C1 PF10363.9 KFM81437.1 - 0.017 15.3 1.9 0.2 11.9 0.2 3.3 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TcpS PF17456.2 KFM81437.1 - 0.028 14.4 3.0 0.087 12.9 3.0 1.9 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S RICTOR_V PF14668.6 KFM81437.1 - 0.03 14.6 7.1 6.9 7.0 0.0 5.6 4 2 3 7 7 7 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 KFM81437.1 - 0.066 13.5 3.8 11 6.7 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat BAG6 PF12057.8 KFM81439.1 - 0.0033 17.1 0.5 0.016 14.9 0.0 2.4 3 0 0 3 3 3 1 BCL2-associated athanogene 6 Suf PF05843.14 KFM81439.1 - 6.5 6.6 8.3 13 5.6 8.3 1.6 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) PHD PF00628.29 KFM81442.1 - 3.8e-07 29.9 7.7 8.1e-07 28.8 7.7 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 KFM81442.1 - 0.0085 16.4 6.1 0.014 15.7 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 KFM81442.1 - 0.015 15.6 3.8 0.038 14.2 3.9 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KFM81442.1 - 0.03 13.9 2.5 0.058 13.0 2.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KFM81442.1 - 0.054 13.7 1.4 0.07 13.3 1.1 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain NPR3 PF03666.13 KFM81442.1 - 0.13 11.1 5.1 0.13 11.0 5.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-RING-like PF08746.11 KFM81442.1 - 0.25 11.7 2.7 0.45 10.9 2.7 1.4 1 0 0 1 1 1 0 RING-like domain DUF4666 PF15697.5 KFM81442.1 - 0.29 11.9 8.2 0.64 10.7 8.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) Presenilin PF01080.17 KFM81442.1 - 0.89 8.2 6.2 0.99 8.1 6.2 1.0 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KFM81442.1 - 7 4.6 5.7 7.3 4.6 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HGTP_anticodon2 PF12745.7 KFM81442.1 - 9.5 5.6 10.9 12 5.4 10.9 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs ING PF12998.7 KFM81443.1 - 5.3e-08 33.4 1.0 6.1e-08 33.2 0.3 1.4 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding AIP3 PF03915.13 KFM81444.1 - 1e-13 51.2 0.3 1.3e-13 50.9 0.3 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 LssY_C PF14067.6 KFM81444.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 LssY C-terminus LRR_8 PF13855.6 KFM81447.1 - 3.4e-45 151.6 84.1 4e-16 58.5 4.5 11.8 3 3 10 14 14 14 13 Leucine rich repeat LRR_4 PF12799.7 KFM81447.1 - 1.3e-26 92.2 93.5 1.9e-05 24.9 6.0 13.5 9 3 5 15 15 15 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM81447.1 - 8.9e-21 74.2 36.4 6.1e-07 29.5 3.0 5.5 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFM81447.1 - 0.00032 20.2 28.9 0.01 15.4 0.3 6.3 2 1 6 8 8 8 5 Leucine-rich repeat LRRNT PF01462.18 KFM81447.1 - 0.006 16.2 3.4 0.006 16.2 3.4 2.9 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFM81447.1 - 0.055 14.0 0.7 0.055 14.0 0.7 16.8 13 4 0 13 13 13 0 Leucine Rich Repeat Epiglycanin_C PF14654.6 KFM81447.1 - 0.1 12.7 0.6 0.21 11.6 0.6 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region VEGFR-2_TMD PF17988.1 KFM81447.1 - 0.59 9.6 2.1 1.2 8.7 2.1 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain FA_hydroxylase PF04116.13 KFM81448.1 - 4.8e-23 82.0 13.8 4.8e-23 82.0 13.8 1.8 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Zip PF02535.22 KFM81449.1 - 0.063 12.5 0.1 0.066 12.4 0.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Med30 PF11315.8 KFM81450.1 - 1.8e-46 158.0 7.0 2.2e-46 157.7 7.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 Syntaxin-6_N PF09177.11 KFM81450.1 - 0.012 16.2 2.0 0.063 13.8 2.0 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DEDD_Tnp_IS110 PF01548.17 KFM81450.1 - 0.11 12.4 0.2 1.4 8.8 0.2 2.2 2 0 0 2 2 2 0 Transposase HisKA PF00512.25 KFM81450.1 - 0.18 11.8 1.9 14 5.8 0.0 2.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain FlgN PF05130.12 KFM81450.1 - 0.23 12.0 4.5 0.23 11.9 2.5 1.8 2 0 0 2 2 2 0 FlgN protein HMG_box PF00505.19 KFM81451.1 - 1e-24 86.7 0.9 1.6e-24 86.1 0.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.8 KFM81451.1 - 8e-12 46.1 0.1 8e-12 46.1 0.1 2.7 2 1 1 3 3 3 1 Sox developmental protein N terminal HMG_box_2 PF09011.10 KFM81451.1 - 7e-10 39.4 0.4 1.3e-09 38.5 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain APC_15aa PF05972.11 KFM81451.1 - 3.5 8.1 5.5 4.6 7.7 0.6 2.7 2 0 0 2 2 2 0 APC 15 residue motif DSPc PF00782.20 KFM81454.1 - 7e-34 116.5 0.0 8.5e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFM81454.1 - 0.00054 20.1 0.1 0.0012 18.9 0.1 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFM81454.1 - 0.0015 18.1 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CHASE6_C PF17150.4 KFM81454.1 - 0.099 13.3 0.1 0.3 11.8 0.0 1.8 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain NaeI PF09126.10 KFM81456.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Restriction endonuclease NaeI Matrilin_ccoil PF10393.9 KFM81456.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin BTB_2 PF02214.22 KFM81457.1 - 0.019 15.3 0.3 0.023 15.0 0.3 1.3 1 1 0 1 1 1 0 BTB/POZ domain PRELI PF04707.14 KFM81459.1 - 5e-51 172.6 0.6 2.4e-50 170.4 0.1 1.9 2 0 0 2 2 2 1 PRELI-like family Synuclein PF01387.17 KFM81459.1 - 0.035 14.3 0.1 0.063 13.5 0.1 1.4 1 0 0 1 1 1 0 Synuclein PRT_C PF08372.10 KFM81460.1 - 1.2e-09 38.1 5.4 5.1e-09 36.1 0.0 2.1 1 1 1 2 2 2 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 KFM81460.1 - 4.3e-07 29.3 1.6 5.4e-07 28.9 1.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 KFM81460.1 - 0.0001 21.8 3.0 0.0003 20.3 3.0 1.7 1 1 0 1 1 1 1 Plant protein of unknown function (DUF639) PIG-P PF08510.12 KFM81460.1 - 0.00086 19.2 0.1 0.00086 19.2 0.1 2.6 2 1 1 3 3 3 1 PIG-P GCIP PF13324.6 KFM81460.1 - 0.0094 15.6 0.7 0.013 15.1 0.7 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Wzy_C PF04932.15 KFM81460.1 - 0.07 12.8 3.4 3.4 7.3 0.9 2.3 1 1 1 2 2 2 0 O-Antigen ligase GP41 PF00517.17 KFM81460.1 - 0.098 12.6 1.6 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Retroviral envelope protein NOA36 PF06524.12 KFM81460.1 - 2.5 7.3 6.1 3.5 6.9 6.1 1.1 1 0 0 1 1 1 0 NOA36 protein Chordopox_G3 PF06129.12 KFM81460.1 - 4.9 7.9 7.6 7.8 7.2 3.6 2.6 2 1 0 2 2 2 0 Chordopoxvirus G3 protein DNA_pol_phi PF04931.13 KFM81460.1 - 9.1 4.2 9.2 12 3.8 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi C2 PF00168.30 KFM81461.1 - 4.6e-25 87.9 0.1 1.2e-24 86.6 0.1 1.7 2 0 0 2 2 2 1 C2 domain BSD PF03909.17 KFM81462.1 - 6.2e-13 48.5 1.0 6.2e-13 48.5 1.0 2.6 3 0 0 3 3 3 1 BSD domain IF-2 PF11987.8 KFM81462.1 - 0.013 15.6 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Translation-initiation factor 2 DASH_Dam1 PF08653.10 KFM81462.1 - 0.058 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 DASH complex subunit Dam1 Na_Ca_ex PF01699.24 KFM81463.1 - 4.3e-46 156.6 39.2 1e-24 87.2 14.0 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein OAD_gamma PF04277.13 KFM81463.1 - 0.024 15.2 0.0 0.024 15.2 0.0 3.2 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain BRO1 PF03097.18 KFM81464.1 - 5.1e-21 74.9 0.1 5.8e-21 74.7 0.1 1.0 1 0 0 1 1 1 1 BRO1-like domain Torsin PF06309.11 KFM81465.1 - 3.8e-42 143.4 0.7 6.3e-42 142.7 0.7 1.4 1 0 0 1 1 1 1 Torsin AAA_2 PF07724.14 KFM81465.1 - 0.017 15.3 0.0 0.044 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFM81465.1 - 0.074 13.3 0.0 2 8.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFM81465.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KFM81465.1 - 0.15 12.4 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AMP-binding PF00501.28 KFM81466.1 - 1.3e-93 314.0 0.0 1.5e-93 313.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM81466.1 - 2.6e-21 76.4 0.1 6.6e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFM81466.1 - 1.5e-19 69.6 0.7 7.6e-19 67.4 0.7 2.3 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus FAM91_C PF14648.6 KFM81467.1 - 3.2e-133 444.7 0.1 3.8e-133 444.5 0.1 1.0 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 KFM81468.1 - 3.6e-147 489.6 0.1 4.3e-147 489.4 0.1 1.0 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.6 KFM81468.1 - 7.7e-10 38.2 0.2 7.7e-10 38.2 0.2 1.6 2 0 0 2 2 2 1 FAM91 C-terminus Sigma_reg_C PF13791.6 KFM81468.1 - 0.041 14.1 0.3 0.14 12.3 0.1 2.0 2 0 0 2 2 2 0 Sigma factor regulator C-terminal AP3D1 PF06375.11 KFM81469.1 - 0.039 14.2 12.1 0.045 14.0 12.1 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 OAD_gamma PF04277.13 KFM81469.1 - 0.29 11.8 3.0 0.32 11.6 3.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SR-25 PF10500.9 KFM81469.1 - 1.6 8.3 18.2 1.5 8.4 18.2 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SH3_9 PF14604.6 KFM81470.1 - 6.6e-40 134.7 2.5 6.4e-16 57.9 0.4 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFM81470.1 - 1.2e-36 124.1 0.2 5.3e-11 41.9 0.1 3.6 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KFM81470.1 - 2.1e-28 97.8 0.2 2.3e-09 36.8 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.16 KFM81470.1 - 6.8e-15 54.6 0.5 2.9e-12 46.2 0.1 2.6 2 0 0 2 2 2 2 Sorbin homologous domain RhoGAP PF00620.27 KFM81471.1 - 5.9e-05 22.9 0.0 9.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain START PF01852.19 KFM81472.1 - 7.8e-35 120.2 0.3 1.1e-34 119.6 0.3 1.1 1 0 0 1 1 1 1 START domain RhoGAP PF00620.27 KFM81472.1 - 2.8e-14 53.2 0.1 5.2e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain DUF4728 PF15860.5 KFM81473.1 - 0.00013 22.6 12.1 0.00013 22.6 12.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4728) Vpu PF00558.19 KFM81473.1 - 0.046 13.5 0.2 0.046 13.5 0.2 3.1 4 0 0 4 4 4 0 Vpu protein DUF4191 PF13829.6 KFM81473.1 - 0.42 9.9 2.5 0.49 9.7 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) DUF373 PF04123.13 KFM81473.1 - 8.7 5.7 10.9 11 5.3 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Guanylate_cyc PF00211.20 KFM81476.1 - 5e-60 202.3 0.1 6e-60 202.0 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFM81476.1 - 9.3e-06 25.2 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Heme NO binding associated DUF4516 PF14990.6 KFM81477.1 - 1.1e-20 73.1 0.2 1.3e-20 72.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) Tim44 PF04280.15 KFM81478.1 - 1.7e-28 99.6 0.6 2.4e-28 99.1 0.6 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 KFM81478.1 - 5.8e-07 28.8 0.0 8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein RNA_pol_Rpb4 PF03874.16 KFM81478.1 - 0.14 12.5 0.4 0.57 10.5 0.2 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF4047 PF13256.6 KFM81479.1 - 0.037 14.2 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Phage_ABA_S PF18066.1 KFM81479.1 - 0.13 12.9 0.1 0.56 10.9 0.0 2.1 2 0 0 2 2 2 0 Phage ABA sandwich domain Bcl-2 PF00452.19 KFM81480.1 - 6.3e-24 84.5 0.2 1.7e-23 83.2 0.0 1.7 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family UPF0175 PF03683.13 KFM81480.1 - 0.021 14.5 0.3 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) Ras PF00071.22 KFM81481.1 - 3.7e-59 198.9 0.3 4.6e-59 198.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM81481.1 - 4.6e-36 123.7 0.1 7.6e-36 123.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM81481.1 - 2.2e-15 56.5 0.1 2.7e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM81481.1 - 8.7e-07 28.7 0.1 4.9e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFM81481.1 - 4.4e-06 26.2 0.0 6.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFM81481.1 - 8.8e-05 22.6 0.1 0.00016 21.8 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM81481.1 - 0.00017 21.0 0.2 0.00021 20.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFM81481.1 - 0.00018 21.5 0.1 0.091 12.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KFM81481.1 - 0.0018 17.8 0.2 0.03 13.8 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 KFM81481.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HLH PF00010.26 KFM81482.1 - 9.8e-14 51.1 1.1 1.7e-13 50.3 1.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HMG_box PF00505.19 KFM81483.1 - 9.2e-15 54.8 0.8 1.6e-14 54.0 0.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM81483.1 - 4.4e-08 33.6 0.8 6.2e-08 33.1 0.8 1.2 1 0 0 1 1 1 1 HMG-box domain Catalase-rel PF06628.12 KFM81483.1 - 0.028 14.6 0.1 0.79 10.0 0.0 2.2 2 0 0 2 2 2 0 Catalase-related immune-responsive HMG_box_5 PF14887.6 KFM81483.1 - 0.044 13.7 1.2 0.077 13.0 1.2 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box 5 zf-H2C2_2 PF13465.6 KFM81484.1 - 3.9e-87 283.1 105.7 1.7e-09 37.7 0.4 15.0 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM81484.1 - 1.2e-75 246.0 110.2 3.5e-06 27.2 0.4 14.1 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81484.1 - 7.1e-51 166.4 105.7 0.00045 20.8 0.8 14.1 14 0 0 14 14 14 14 C2H2-type zinc finger zf-met PF12874.7 KFM81484.1 - 4.5e-35 119.0 90.7 0.00044 20.5 0.2 14.2 14 0 0 14 14 14 14 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM81484.1 - 7.5e-34 115.3 69.3 0.0091 16.3 0.2 14.3 14 0 0 14 14 14 14 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM81484.1 - 2.5e-25 87.9 91.4 0.00012 22.0 0.3 14.3 14 0 0 14 14 14 12 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM81484.1 - 3.1e-20 71.6 75.5 0.0026 17.5 0.8 14.5 14 0 0 14 14 14 10 C2H2-type zinc-finger domain BolA PF01722.18 KFM81484.1 - 7.8e-10 38.9 23.5 0.0082 16.4 0.3 8.8 1 1 8 10 10 10 3 BolA-like protein GAGA PF09237.11 KFM81484.1 - 8.1e-09 35.2 31.6 0.3 10.9 0.0 10.6 2 1 9 11 11 11 3 GAGA factor zf-C2H2_2 PF12756.7 KFM81484.1 - 3.1e-06 27.5 90.7 0.27 11.6 0.8 13.2 1 1 11 12 12 12 5 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM81484.1 - 0.00011 22.0 54.0 1.6 8.6 0.1 12.9 4 4 10 14 14 14 2 C2H2 type zinc-finger (1 copy) DUF952 PF06108.12 KFM81484.1 - 0.0024 17.9 1.1 36 4.4 0.0 5.3 2 2 3 6 6 6 0 Protein of unknown function (DUF952) zf-MYST PF17772.1 KFM81484.1 - 0.0062 16.1 62.7 0.38 10.4 0.3 12.1 5 2 9 14 14 14 3 MYST family zinc finger domain Tox-HNH-HHH PF15637.6 KFM81484.1 - 0.063 13.4 2.4 14 5.9 0.0 3.6 2 1 2 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-RRPl_C4 PF17026.5 KFM81484.1 - 0.083 13.0 61.2 0.25 11.5 7.7 6.4 1 1 7 8 8 8 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2415 PF10313.9 KFM81484.1 - 0.15 12.0 5.2 22 5.1 0.1 4.4 5 0 0 5 5 5 0 Uncharacterised protein domain (DUF2415) Alk_phosphatase PF00245.20 KFM81484.1 - 0.22 10.4 0.9 0.67 8.8 0.1 1.8 1 1 0 2 2 2 0 Alkaline phosphatase zf_UBZ PF18439.1 KFM81484.1 - 0.35 10.5 0.1 0.35 10.5 0.1 12.0 14 0 0 14 14 14 0 Ubiquitin-Binding Zinc Finger Peptidase_M15_2 PF05951.13 KFM81484.1 - 0.94 9.1 5.9 22 4.7 0.2 4.4 1 1 3 5 5 5 0 Bacterial protein of unknown function (DUF882) zf-C2HC_2 PF13913.6 KFM81484.1 - 1.9 8.5 51.8 1.7 8.6 0.1 11.2 12 0 0 12 12 12 0 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM81484.1 - 1.9 8.6 48.8 0.91 9.6 0.6 12.1 12 2 2 14 14 14 0 Sec23/Sec24 zinc finger zinc_ribbon_15 PF17032.5 KFM81484.1 - 7.2 7.4 59.6 1.5 9.6 2.0 7.1 3 2 6 9 9 9 0 zinc-ribbon family zf-C2H2_8 PF15909.5 KFM81484.1 - 8.4 6.8 53.9 1.1 9.6 7.5 6.4 1 1 5 6 6 6 0 C2H2-type zinc ribbon TGT PF01702.18 KFM81487.1 - 2.2e-150 500.7 0.0 2.7e-150 500.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase CBM_14 PF01607.24 KFM81488.1 - 7.5e-45 150.9 49.4 1.1e-09 38.3 3.7 6.1 6 0 0 6 6 6 5 Chitin binding Peritrophin-A domain MGC-24 PF05283.11 KFM81488.1 - 1.9 9.0 15.2 8.1 6.9 15.2 2.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HEAT PF02985.22 KFM81489.1 - 5.1e-07 29.4 0.7 0.0052 16.9 0.0 3.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KFM81489.1 - 0.00078 19.8 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KFM81489.1 - 0.0071 16.9 0.0 0.031 14.9 0.0 2.0 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region DNA_pol_phi PF04931.13 KFM81489.1 - 0.014 13.5 0.1 0.017 13.3 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi UBA_6 PF18039.1 KFM81489.1 - 0.027 14.4 0.1 0.097 12.6 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain RTP1_C1 PF10363.9 KFM81489.1 - 0.06 13.5 0.0 0.093 12.9 0.0 1.4 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 PatG_C PF18065.1 KFM81492.1 - 0.064 13.2 0.9 0.14 12.1 0.2 1.9 2 0 0 2 2 2 0 PatG C-terminal RRM_1 PF00076.22 KFM81493.1 - 1e-17 63.7 0.0 1.3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM81493.1 - 2e-05 24.2 0.0 2.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM81493.1 - 9.7e-05 22.4 0.0 0.00026 21.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KFM81493.1 - 0.0062 16.4 0.0 0.0084 15.9 0.0 1.1 1 0 0 1 1 1 1 Occluded RNA-recognition motif SET_assoc PF11767.8 KFM81493.1 - 0.031 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 KFM81493.1 - 0.078 13.0 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif RRM_1 PF00076.22 KFM81494.1 - 1.6e-18 66.3 0.0 2.1e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM81494.1 - 7.5e-05 22.3 0.0 0.0001 21.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM81494.1 - 0.002 18.2 0.0 0.0045 17.1 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KFM81494.1 - 0.029 14.4 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif RNA_bind PF08675.11 KFM81494.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain Limkain-b1 PF11608.8 KFM81494.1 - 0.18 11.9 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 SET_assoc PF11767.8 KFM81494.1 - 0.23 11.1 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated YqaJ PF09588.10 KFM81495.1 - 3.2e-10 40.3 0.0 6.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain Dcc1 PF09724.9 KFM81496.1 - 3.1e-88 296.3 0.6 3.6e-88 296.1 0.6 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 GFO_IDH_MocA PF01408.22 KFM81497.1 - 1.1e-21 77.9 0.2 1.6e-21 77.4 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Metallophos PF00149.28 KFM81499.1 - 6.4e-12 46.4 0.1 8.9e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM81499.1 - 1.9e-05 24.9 0.0 2.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Astacin PF01400.24 KFM81502.1 - 5e-13 49.1 0.0 5.3e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 KFM81503.1 - 2.1e-38 131.8 0.0 2.6e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFM81503.1 - 0.049 12.6 0.0 0.049 12.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.24 KFM81504.1 - 2.2e-47 161.2 0.4 2.6e-47 160.9 0.4 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 KFM81505.1 - 6.6e-48 162.9 0.5 7.9e-48 162.6 0.5 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 KFM81506.1 - 3.7e-52 176.7 0.0 4.5e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Phage_connector PF05352.12 KFM81506.1 - 0.092 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage Connector (GP10) ADH_N PF08240.12 KFM81507.1 - 2e-30 104.9 2.4 2e-30 104.9 2.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM81507.1 - 2.4e-21 76.0 0.0 3.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFM81507.1 - 3.3e-12 46.3 0.3 2.8e-10 40.1 0.2 2.1 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFM81507.1 - 0.00041 21.4 0.0 0.002 19.2 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFM81507.1 - 0.021 14.1 0.3 0.034 13.5 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KFM81507.1 - 0.047 13.1 1.1 0.079 12.3 1.1 1.3 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 KFM81507.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-C2H2 PF00096.26 KFM81508.1 - 1.4e-27 94.5 64.6 3.3e-05 24.1 1.8 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM81508.1 - 2.4e-17 62.5 70.1 0.00012 22.3 0.5 10.0 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM81508.1 - 1.3e-16 59.9 61.6 0.016 16.0 0.9 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM81508.1 - 0.00025 21.2 44.7 0.06 13.7 1.0 8.8 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFM81508.1 - 0.00033 20.9 6.2 0.00033 20.9 6.2 5.0 1 1 4 5 5 5 2 C2H2-type zinc ribbon IBR PF01485.21 KFM81508.1 - 0.00064 19.9 33.1 0.23 11.7 4.3 5.6 1 1 3 4 4 4 3 IBR domain, a half RING-finger domain zf_Hakai PF18408.1 KFM81508.1 - 0.0063 16.2 0.0 0.0063 16.2 0.0 7.1 8 1 1 9 9 9 1 C2H2 Hakai zinc finger domain PyrI_C PF02748.15 KFM81508.1 - 0.041 13.8 1.5 0.041 13.8 1.5 3.9 3 1 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.6 KFM81508.1 - 0.059 13.4 33.4 0.15 12.1 1.3 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM81508.1 - 0.86 9.6 18.2 2.9 7.9 0.1 6.3 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Ribosomal_L34e PF01199.18 KFM81508.1 - 2.8 8.3 7.7 16 5.9 0.1 3.2 3 0 0 3 3 3 0 Ribosomal protein L34e Peptidase_C78 PF07910.13 KFM81509.1 - 6.2e-36 123.9 2.3 7.5e-36 123.6 2.3 1.0 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 KFM81509.1 - 0.05 13.0 1.8 0.24 10.8 0.9 1.9 1 1 0 2 2 2 0 Peptidase family C54 E1_DerP2_DerF2 PF02221.15 KFM81512.1 - 3.6e-14 53.3 0.0 4.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 ML domain Hairy_orange PF07527.13 KFM81513.1 - 1.1e-18 67.1 1.2 1.8e-18 66.5 0.1 2.0 3 0 0 3 3 3 1 Hairy Orange HLH PF00010.26 KFM81513.1 - 3e-17 62.3 4.4 7.9e-17 61.0 4.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CHGN PF05679.16 KFM81515.1 - 4.9e-126 421.6 2.3 6.1e-126 421.3 2.3 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase PAN_1 PF00024.26 KFM81516.1 - 4.5e-12 45.8 27.2 1.3e-07 31.5 1.2 5.6 4 1 2 6 6 6 4 PAN domain PAN_4 PF14295.6 KFM81516.1 - 0.031 14.2 23.5 0.14 12.1 1.3 5.1 5 0 0 5 5 5 0 PAN domain adh_short PF00106.25 KFM81517.1 - 4.6e-30 104.5 0.0 2.7e-29 102.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM81517.1 - 4.1e-13 49.4 0.0 2.4e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM81517.1 - 3.3e-06 27.2 0.0 4.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KFM81517.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KFM81517.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 KFM81517.1 - 0.057 13.9 0.0 0.12 12.9 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 KFM81517.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase UQ_con PF00179.26 KFM81518.1 - 6.7e-44 148.9 0.0 8.4e-44 148.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 KFM81518.1 - 3.9e-07 29.9 0.0 8.3e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 KFM81518.1 - 3.3e-06 26.8 0.0 5.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFM81518.1 - 0.0014 18.9 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain UBA_4 PF14555.6 KFM81518.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UEV PF05743.13 KFM81518.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 UEV domain S_100 PF01023.19 KFM81519.1 - 0.74 9.6 5.1 9.9 6.0 0.1 3.4 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain GNT-I PF03071.15 KFM81521.1 - 8.5e-08 31.4 0.0 9.9e-08 31.2 0.0 1.1 1 0 0 1 1 1 1 GNT-I family ketoacyl-synt PF00109.26 KFM81523.1 - 0.19 11.3 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain PDDEXK_5 PF11645.8 KFM81524.1 - 0.026 14.5 0.1 0.033 14.1 0.1 1.1 1 0 0 1 1 1 0 PD-(D/E)XK endonuclease RRM_1 PF00076.22 KFM81525.1 - 1.3e-11 44.2 0.9 4.6e-11 42.4 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM81525.1 - 0.013 15.4 0.3 0.058 13.4 0.2 2.2 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFM81525.1 - 0.12 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 KFM81525.1 - 0.14 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 KFM81525.1 - 0.62 10.1 0.0 0.62 10.1 0.0 2.5 3 0 0 3 3 3 0 RNA binding motif PEP-utilizers PF00391.23 KFM81527.1 - 4e-05 23.3 0.0 7.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PPDK_N PF01326.19 KFM81527.1 - 0.00045 19.6 0.0 0.001 18.4 0.0 1.6 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF3216 PF11505.8 KFM81527.1 - 0.2 11.9 0.6 0.57 10.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) Astacin PF01400.24 KFM81528.1 - 1.8e-59 200.6 0.0 2.1e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 KFM81529.1 - 3.1e-58 196.6 0.0 3.5e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 KFM81530.1 - 3.6e-51 173.5 0.2 4e-51 173.4 0.2 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM81530.1 - 0.071 12.9 2.3 0.5 10.2 0.7 2.1 1 1 0 2 2 2 0 Matrixin UQ_con PF00179.26 KFM81532.1 - 9.3e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFM81532.1 - 8e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KFM81532.1 - 0.012 15.9 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 RWD domain cwf18 PF08315.12 KFM81533.1 - 1.5e-35 122.8 14.9 1.8e-35 122.5 14.9 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Arg_tRNA_synt_N PF03485.16 KFM81533.1 - 0.13 12.8 0.5 0.32 11.6 0.2 1.7 1 1 1 2 2 2 0 Arginyl tRNA synthetase N terminal domain Gag_p30 PF02093.16 KFM81533.1 - 0.26 10.8 3.5 7.8 6.0 0.4 2.3 2 1 0 2 2 2 0 Gag P30 core shell protein Pkinase PF00069.25 KFM81534.1 - 3.3e-36 125.0 0.0 4.5e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM81534.1 - 1.6e-15 57.1 0.0 2.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM81534.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM81534.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM81534.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFM81534.1 - 0.036 12.8 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KFM81534.1 - 0.14 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFM81534.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KFM81535.1 - 1.2e-06 28.2 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ub-Mut7C PF14451.6 KFM81535.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Mut7-C ubiquitin zf-C2H2_4 PF13894.6 KFM81536.1 - 1.7e-06 28.4 12.0 0.004 17.9 2.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM81536.1 - 4.5e-06 26.8 13.4 0.00087 19.6 2.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KFM81536.1 - 0.00034 21.3 1.7 0.00051 20.7 1.7 1.3 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KFM81536.1 - 0.0019 18.5 9.4 0.24 11.7 1.4 2.4 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFM81536.1 - 0.0027 17.7 13.9 0.026 14.5 0.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met2 PF12907.7 KFM81536.1 - 0.0063 16.6 2.7 0.0063 16.6 2.7 2.0 2 0 0 2 2 2 1 Zinc-binding zf-Di19 PF05605.12 KFM81536.1 - 0.017 15.4 6.3 0.23 11.8 0.2 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KFM81536.1 - 0.11 12.9 12.2 0.26 11.8 0.6 3.6 3 0 0 3 3 3 0 Zinc-finger double domain FOXP-CC PF16159.5 KFM81536.1 - 0.12 13.0 3.1 12 6.6 0.1 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KFM81536.1 - 0.23 11.2 0.5 0.23 11.2 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.7 KFM81536.1 - 0.31 11.5 6.9 0.14 12.6 2.5 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.15 KFM81536.1 - 0.76 9.8 11.3 0.47 10.5 1.9 2.8 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_9 PF16293.5 KFM81536.1 - 1.2 9.0 6.2 4.8 7.1 0.2 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) IspD PF01128.19 KFM81537.1 - 5.9e-32 111.2 0.0 7.2e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 KFM81537.1 - 2.5e-05 24.7 0.0 3.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 KFM81537.1 - 0.0035 17.3 0.2 0.014 15.4 0.1 1.9 2 1 0 2 2 2 1 Cytidylyltransferase DAZAP2 PF11029.8 KFM81538.1 - 1.5e-28 100.3 21.4 2.7e-28 99.5 21.4 1.5 1 1 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) Trypsin PF00089.26 KFM81539.1 - 4.5e-66 222.8 0.1 5.2e-66 222.6 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM81539.1 - 4.3e-06 27.1 0.1 8.9e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFM81539.1 - 0.00012 23.1 0.0 0.00029 21.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain MFS_1 PF07690.16 KFM81542.1 - 0.01 14.8 0.0 0.011 14.7 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFM81542.1 - 0.14 11.1 0.1 0.17 10.9 0.1 1.0 1 0 0 1 1 1 0 Nucleoside H+ symporter CH PF00307.31 KFM81544.1 - 1e-08 35.3 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain SEN1_N PF12726.7 KFM81544.1 - 0.025 12.8 0.0 0.029 12.6 0.0 1.0 1 0 0 1 1 1 0 SEN1 N terminal CfAFP PF05264.11 KFM81544.1 - 0.5 10.3 8.2 1.5 8.8 7.2 1.9 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Spectrin PF00435.21 KFM81545.1 - 6.8e-15 55.4 51.4 3.1e-06 27.6 7.2 5.4 5 0 0 5 5 5 5 Spectrin repeat HSBP1 PF06825.12 KFM81545.1 - 0.019 14.8 0.3 0.019 14.8 0.3 3.8 4 0 0 4 4 4 0 Heat shock factor binding protein 1 NAS PF03059.16 KFM81545.1 - 0.12 11.7 1.7 0.34 10.2 0.6 2.0 2 0 0 2 2 2 0 Nicotianamine synthase protein Baculo_PEP_C PF04513.12 KFM81545.1 - 0.24 11.4 7.0 0.35 10.9 0.0 3.4 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 KFM81546.1 - 3.7e-207 673.4 281.5 6.4e-15 55.5 4.2 31.4 31 1 0 31 31 31 29 Spectrin repeat NanE PF04131.14 KFM81546.1 - 0.0094 15.2 3.4 1.6 7.9 0.0 3.3 3 0 0 3 3 3 2 Putative N-acetylmannosamine-6-phosphate epimerase DUF4055 PF13264.6 KFM81546.1 - 0.38 10.9 4.7 2.1 8.5 0.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) DUF3741 PF12552.8 KFM81546.1 - 1.2 9.2 5.6 1.1e+02 2.9 0.2 5.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3741) Neur_chan_memb PF02932.16 KFM81547.1 - 4.7 7.2 7.1 6.4 6.8 7.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L30 PF00327.20 KFM81548.1 - 7.7e-07 28.9 0.1 1.5e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RRM_1 PF00076.22 KFM81549.1 - 3.1e-16 58.9 0.0 4.1e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KFM81549.1 - 0.05 13.5 0.1 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 KFM81549.1 - 0.056 13.3 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF5413 PF17434.2 KFM81550.1 - 0.059 13.7 0.0 0.065 13.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5413) Glyco_hydro_2 PF00703.21 KFM81551.1 - 5.8 7.6 14.2 1.8 9.3 1.2 5.5 3 1 1 4 4 4 0 Glycosyl hydrolases family 2 MLD PF11647.8 KFM81552.1 - 0.019 15.2 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Membrane Localization Domain Ints3 PF10189.9 KFM81553.1 - 4.4e-107 356.5 0.3 1e-106 355.3 0.3 1.7 1 0 0 1 1 1 1 Integrator complex subunit 3 WGG PF10273.9 KFM81553.1 - 0.61 10.8 4.3 35 5.1 0.0 3.7 3 1 0 3 3 3 0 Pre-rRNA-processing protein TSR2 Pilosulin PF17499.2 KFM81554.1 - 0.012 15.8 5.6 0.012 15.8 5.6 14.4 1 1 13 14 14 14 0 Ant venom peptides DUF1822 PF08852.11 KFM81554.1 - 0.95 8.4 9.5 1.3 8.0 4.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1822) DUF848 PF05852.11 KFM81554.1 - 2.5 8.2 38.2 1.7 8.7 2.4 6.7 1 1 6 7 7 7 0 Gammaherpesvirus protein of unknown function (DUF848) PAS_4 PF08448.10 KFM81558.1 - 1.9e-05 24.8 1.6 46 4.3 0.0 6.6 1 1 5 7 7 7 2 PAS fold Cthe_2159 PF14262.6 KFM81558.1 - 0.058 12.7 9.0 1.5 8.1 4.4 3.7 1 1 1 2 2 2 0 Carbohydrate-binding domain-containing protein Cthe_2159 PAS_4 PF08448.10 KFM81559.1 - 0.063 13.5 0.0 2.5 8.4 0.0 2.2 1 1 1 2 2 2 0 PAS fold Myb_DNA-binding PF00249.31 KFM81561.1 - 1.1e-16 60.7 0.6 5.6e-12 45.7 0.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain GPS2_interact PF15784.5 KFM81561.1 - 5.3e-14 52.4 6.8 5.3e-14 52.4 6.8 3.6 2 0 0 2 2 2 1 G-protein pathway suppressor 2-interacting domain Myb_DNA-bind_6 PF13921.6 KFM81561.1 - 8.9e-09 35.5 4.0 8.8e-05 22.7 0.5 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4482 PF14818.6 KFM81561.1 - 0.016 16.1 1.3 0.016 16.1 1.3 6.5 7 1 0 8 8 8 0 Domain of unknown function (DUF4482) Annexin PF00191.20 KFM81561.1 - 0.1 12.7 0.3 0.26 11.4 0.3 1.7 1 0 0 1 1 1 0 Annexin XhlA PF10779.9 KFM81561.1 - 9.3 6.5 7.0 2.5 8.4 1.8 2.4 2 0 0 2 2 2 0 Haemolysin XhlA MMR_HSR1 PF01926.23 KFM81563.1 - 4e-17 62.3 0.1 2.6e-14 53.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM81563.1 - 3.9e-07 29.7 0.2 4.4e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM81563.1 - 4e-05 23.6 0.0 0.0053 16.7 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFM81563.1 - 0.00033 20.3 0.0 0.15 11.6 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFM81563.1 - 0.0014 18.7 0.3 0.0014 18.7 0.3 3.0 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.16 KFM81563.1 - 0.028 13.8 0.1 1 8.7 0.0 2.5 2 0 0 2 2 2 0 AIG1 family CCM2_C PF16545.5 KFM81563.1 - 0.038 14.5 0.3 0.084 13.4 0.3 1.6 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology Npun_R1517 PF18068.1 KFM81563.1 - 0.062 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Npun R1517 Roc PF08477.13 KFM81563.1 - 0.1 12.8 0.2 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Acetyltransf_16 PF05301.11 KFM81565.1 - 1.3e-39 135.8 0.0 1.4e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_1 PF00583.25 KFM81565.1 - 0.022 15.0 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM81565.1 - 0.079 13.4 0.0 0.094 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM81565.1 - 0.17 11.9 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.32 KFM81569.1 - 2.6e-46 154.6 33.7 5.9e-10 39.6 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM81569.1 - 2.6e-19 69.3 5.2 0.037 14.3 0.0 6.7 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KFM81569.1 - 3.7e-08 31.9 0.6 6.5e-08 31.1 0.6 1.3 1 0 0 1 1 1 1 IKI3 family eIF2A PF08662.11 KFM81569.1 - 4.3e-06 26.7 1.2 8.6e-05 22.5 0.1 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFM81569.1 - 8.8e-05 21.6 0.2 0.22 10.4 0.0 4.4 2 1 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 KFM81569.1 - 0.0032 17.1 0.0 0.24 10.9 0.0 2.6 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 Coatomer_WDAD PF04053.14 KFM81569.1 - 0.0098 15.0 1.6 0.74 8.8 0.8 2.5 1 1 1 2 2 2 2 Coatomer WD associated region LRR_8 PF13855.6 KFM81572.1 - 3.7e-39 132.3 39.9 1e-12 47.6 6.5 8.8 7 2 4 11 11 11 7 Leucine rich repeat LRR_4 PF12799.7 KFM81572.1 - 1.2e-23 82.8 44.7 0.00024 21.4 6.4 10.8 9 2 3 12 12 12 8 Leucine Rich repeats (2 copies) TIR PF01582.20 KFM81572.1 - 1.8e-19 70.2 0.3 3.1e-19 69.4 0.3 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFM81572.1 - 1.7e-15 57.6 0.0 5e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 KFM81572.1 - 7.8e-09 35.3 15.7 0.00072 19.1 0.6 5.4 2 1 2 6 6 6 4 Leucine-rich repeat LRR_5 PF13306.6 KFM81572.1 - 6.2e-05 23.0 6.3 0.065 13.2 0.2 4.0 3 1 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM81572.1 - 0.048 14.2 31.8 42 5.3 0.0 12.0 11 2 0 11 11 11 0 Leucine Rich Repeat LCE6A PF15858.5 KFM81572.1 - 0.19 12.5 1.2 2 9.2 0.5 2.2 2 0 0 2 2 2 0 Late cornified envelope protein 6A family p450 PF00067.22 KFM81573.1 - 4.2e-42 144.5 4.8 3.7e-40 138.1 4.8 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM81574.1 - 9.9e-48 163.0 0.2 1.1e-47 162.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 fn3 PF00041.21 KFM81576.1 - 2.9e-09 37.1 0.1 0.0016 18.8 0.0 2.1 2 0 0 2 2 2 2 Fibronectin type III domain I-set PF07679.16 KFM81577.1 - 3.7e-34 116.6 0.0 2.8e-15 56.2 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM81577.1 - 1.9e-33 114.9 0.1 6.5e-14 52.3 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM81577.1 - 2.3e-24 85.5 0.0 4.4e-11 43.0 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM81577.1 - 2.4e-20 72.5 0.0 2.4e-06 27.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM81577.1 - 2.9e-12 46.7 1.2 0.0014 18.8 0.2 4.8 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM81577.1 - 2.3e-09 37.2 0.0 0.0015 18.6 0.0 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFM81577.1 - 4.4e-06 26.6 0.0 0.029 14.4 0.0 3.4 2 1 1 3 3 3 2 C17orf99 Ig domain Ig_6 PF18452.1 KFM81577.1 - 0.0001 21.8 0.0 0.0063 16.0 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain C1-set PF07654.15 KFM81577.1 - 0.0015 18.8 0.1 0.011 16.0 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM81577.1 - 0.0041 17.3 0.0 3.3 8.1 0.0 3.3 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFM81577.1 - 0.056 13.4 0.0 4.2 7.4 0.0 2.6 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain tRNA_anti-like PF12869.7 KFM81577.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like PMT PF02366.18 KFM81578.1 - 9.4e-76 254.6 19.2 9.4e-76 254.6 19.2 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFM81578.1 - 2.4e-56 190.5 13.9 2.4e-56 190.5 13.9 2.3 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFM81578.1 - 1.1e-29 103.6 0.2 1.8e-29 103.0 0.2 1.2 1 0 0 1 1 1 1 MIR domain MULE PF10551.9 KFM81580.1 - 7.2e-07 29.5 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain RNA_pol_Rpb1_1 PF04997.12 KFM81581.1 - 3.4e-18 66.1 0.5 3.8e-18 65.9 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KFM81582.1 - 5.9e-25 88.4 0.0 6.8e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KFM81582.1 - 0.00016 21.2 1.9 0.00023 20.6 1.9 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KFM81583.1 - 3.3e-44 151.3 0.0 6.3e-44 150.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 KFM81583.1 - 7.2e-39 133.2 0.0 1.6e-38 132.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_2 PF00623.20 KFM81583.1 - 1.4e-36 126.3 0.0 2.5e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_4 PF05000.17 KFM81583.1 - 4e-35 120.0 0.1 1e-34 118.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 KFM81585.1 - 7e-07 28.9 0.0 8.5e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 SIP1 PF04938.12 KFM81586.1 - 4.3e-19 69.1 0.0 5.7e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) GMC_oxred_N PF00732.19 KFM81587.1 - 2.3e-12 46.9 0.0 2.8e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KFM81587.1 - 4.1e-05 22.9 0.0 5.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KFM81587.1 - 4.7e-05 23.5 0.1 7.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM81587.1 - 0.0012 18.5 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFM81587.1 - 0.0041 16.2 0.1 0.005 15.9 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFM81587.1 - 0.0099 15.1 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM81587.1 - 0.02 13.6 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KFM81587.1 - 0.034 13.2 0.1 0.04 13.0 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 KFM81587.1 - 0.15 11.2 0.0 0.15 11.2 0.0 1.0 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.19 KFM81588.1 - 3.8e-52 177.5 0.0 4.5e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFM81588.1 - 4.4e-07 30.5 0.0 8.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFM81589.1 - 1.6e-17 64.4 0.1 1.8e-17 64.2 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Surp PF01805.20 KFM81590.1 - 1.6e-23 82.5 0.5 2e-23 82.1 0.5 1.1 1 0 0 1 1 1 1 Surp module PRP21_like_P PF12230.8 KFM81591.1 - 2.1e-27 96.4 6.5 3.3e-27 95.8 6.5 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KFM81591.1 - 3e-07 30.3 4.2 5.5e-07 29.5 4.2 1.5 1 0 0 1 1 1 1 Surp module BUD22 PF09073.10 KFM81591.1 - 0.012 15.0 6.7 0.014 14.8 6.7 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 KFM81591.1 - 0.33 9.0 4.3 0.44 8.6 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3391 PF11871.8 KFM81591.1 - 0.97 10.0 10.6 0.45 11.1 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DNA_pol3_a_NII PF11490.8 KFM81591.1 - 1.2 9.1 9.6 4.8 7.1 1.6 2.2 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II ubiquitin PF00240.23 KFM81592.1 - 5.7e-14 51.6 0.0 1.4e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KFM81592.1 - 0.016 15.7 0.1 0.054 14.0 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain ATF7IP_BD PF16788.5 KFM81592.1 - 8.8 6.4 16.3 0.81 9.7 11.6 1.5 2 0 0 2 2 2 0 ATF-interacting protein binding domain Condensin2nSMC PF12422.8 KFM81595.1 - 1.8e-24 86.6 1.1 1.8e-24 86.6 1.1 2.6 2 1 1 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit HEPN_Apea PF18739.1 KFM81595.1 - 0.06 13.8 3.9 0.12 12.8 0.8 2.8 1 1 1 2 2 2 0 Apea-like HEPN FDX-ACB PF03147.14 KFM81595.1 - 0.15 12.5 0.6 0.48 10.9 0.2 2.1 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain CCDC92 PF14916.6 KFM81596.1 - 1.1e-14 53.9 6.6 2.2e-14 52.9 1.0 2.7 2 0 0 2 2 2 1 Coiled-coil domain of unknown function ATG16 PF08614.11 KFM81596.1 - 0.0032 17.7 5.5 0.0032 17.7 5.5 2.3 1 1 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF29 PF01724.16 KFM81596.1 - 0.0044 17.3 2.3 0.011 16.0 2.3 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF29 Lzipper-MIP1 PF14389.6 KFM81596.1 - 0.061 13.6 0.8 0.061 13.6 0.8 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1192 PF06698.11 KFM81596.1 - 0.094 12.8 0.4 0.094 12.8 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FlaC_arch PF05377.11 KFM81596.1 - 0.2 12.0 4.9 0.13 12.6 1.4 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Med9 PF07544.13 KFM81596.1 - 0.27 11.4 6.5 0.063 13.4 1.6 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 WD40_alt PF14077.6 KFM81596.1 - 2 8.4 6.7 4.5 7.2 0.2 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif DivIC PF04977.15 KFM81596.1 - 2 8.2 8.7 9.3 6.1 0.9 3.4 2 1 1 3 3 3 0 Septum formation initiator ABC_tran_CTD PF16326.5 KFM81596.1 - 5.7 7.3 7.5 0.84 9.9 1.9 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 KFM81596.1 - 6.2 7.1 11.1 12 6.2 5.7 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 KFM81596.1 - 8.2 5.2 6.2 11 4.8 6.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_L29 PF00831.23 KFM81596.1 - 9.8 6.2 10.9 9.3 6.3 0.1 3.3 1 1 2 3 3 3 0 Ribosomal L29 protein Pkinase_Tyr PF07714.17 KFM81597.1 - 0.053 12.8 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KFM81598.1 - 5.6e-63 212.6 0.0 6.9e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM81598.1 - 5.1e-32 111.3 0.0 6.5e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KFM81598.1 - 0.00099 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM81598.1 - 0.0022 17.9 0.0 0.0047 16.9 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM81598.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM81598.1 - 0.027 13.8 0.0 0.052 12.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Furin-like PF00757.20 KFM81599.1 - 3.7e-39 134.0 89.5 5e-26 91.4 41.5 4.2 2 1 2 4 4 4 3 Furin-like cysteine rich region Recep_L_domain PF01030.24 KFM81599.1 - 1.5e-34 118.5 0.2 4.6e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.6 KFM81599.1 - 4.3e-31 107.4 86.4 7e-26 90.6 32.3 5.4 2 1 1 3 3 3 3 Growth factor receptor domain IV zf-H2C2_2 PF13465.6 KFM81600.1 - 3.6e-62 204.2 92.8 9.3e-08 32.2 1.4 12.1 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM81600.1 - 4.5e-48 159.1 104.9 2.3e-06 27.7 2.1 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81600.1 - 5.4e-31 104.6 98.2 0.00021 21.9 1.6 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM81600.1 - 1.8e-11 43.7 91.5 0.0017 18.3 1.0 12.1 11 3 0 11 11 11 8 C2H2-type zinc finger zf-met PF12874.7 KFM81600.1 - 1.1e-08 35.2 81.8 0.0023 18.3 0.9 10.5 11 0 0 11 11 10 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM81600.1 - 1.4e-06 28.4 72.7 0.091 13.1 0.6 10.6 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding Baculo_IE-1 PF05290.11 KFM81600.1 - 7.3e-05 22.7 33.9 0.15 12.0 0.4 7.7 1 1 4 6 6 6 2 Baculovirus immediate-early protein (IE-0) zf-RRPl_C4 PF17026.5 KFM81600.1 - 8.6e-05 22.6 42.4 0.03 14.4 7.1 4.2 2 1 2 4 4 4 4 Putative ribonucleoprotein zinc-finger pf C4 type BolA PF01722.18 KFM81600.1 - 0.0001 22.5 19.7 2.2 8.6 0.1 6.0 3 3 4 7 7 7 2 BolA-like protein zf-H2C2_5 PF13909.6 KFM81600.1 - 0.00025 20.7 75.7 0.48 10.2 0.1 11.9 11 1 0 11 11 10 6 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KFM81600.1 - 0.0043 16.9 42.6 1.9 8.5 0.0 10.1 11 0 0 11 11 10 2 zinc-finger of a C2HC-type FYVE PF01363.21 KFM81600.1 - 0.24 11.5 60.8 31 4.8 0.4 7.4 1 1 4 5 5 4 0 FYVE zinc finger VATC PF18716.1 KFM81600.1 - 0.35 10.7 33.0 12 5.9 0.0 9.2 10 0 0 10 10 10 0 Vms1-associating treble clef domain zinc_ribbon_15 PF17032.5 KFM81600.1 - 0.6 10.9 45.9 1 10.1 2.2 5.7 1 1 7 8 8 8 0 zinc-ribbon family zf_UBZ PF18439.1 KFM81600.1 - 2.3 7.9 49.2 3.1 7.5 0.7 10.0 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM81600.1 - 5.7 7.3 78.0 0.64 10.4 3.2 9.4 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFM81600.1 - 7 6.9 38.9 8 6.7 1.1 7.2 6 1 1 7 7 7 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 KFM81600.1 - 8.8 7.0 44.1 42 4.8 0.1 7.3 3 3 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats PRE_C2HC PF07530.11 KFM81601.1 - 2.6e-06 27.4 0.2 6.4e-06 26.2 0.2 1.7 1 0 0 1 1 1 1 Associated with zinc fingers Pedibin PF08182.11 KFM81601.1 - 0.019 14.7 0.6 0.038 13.8 0.6 1.4 1 0 0 1 1 1 0 Pedibin/Hym-346 family Jiv90 PF14901.6 KFM81601.1 - 2.7 8.2 8.7 1.2 9.3 3.3 2.7 2 1 1 3 3 3 0 Cleavage inducing molecular chaperone PHtD_u1 PF16645.5 KFM81601.1 - 4.3 7.9 8.5 1.2e+02 3.2 8.5 2.5 1 1 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein Proteasome PF00227.26 KFM81604.1 - 1.2e-53 181.4 0.0 1.5e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM81604.1 - 6.3e-14 51.3 0.0 1.3e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature IL12 PF03039.14 KFM81604.1 - 0.0046 16.3 0.1 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 Interleukin-12 alpha subunit IKI3 PF04762.12 KFM81605.1 - 9.3e-103 345.0 0.0 1e-102 344.8 0.0 1.0 1 0 0 1 1 1 1 IKI3 family Coatomer_WDAD PF04053.14 KFM81605.1 - 6.4e-05 22.2 0.0 0.00027 20.1 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 KFM81605.1 - 0.00011 22.4 0.1 0.29 11.5 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 KFM81605.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.8 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region IKI3 PF04762.12 KFM81606.1 - 9.3e-108 361.5 9.9 1.6e-107 360.7 9.9 1.4 1 0 0 1 1 1 1 IKI3 family Aconitase_B_N PF11791.8 KFM81606.1 - 0.053 13.6 0.1 0.17 11.9 0.1 2.0 1 0 0 1 1 1 0 Aconitate B N-terminal domain Cucumopine_C PF18631.1 KFM81606.1 - 0.09 12.7 1.6 0.28 11.1 0.5 2.4 2 0 0 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain TPR_1 PF00515.28 KFM81606.1 - 0.29 11.0 2.5 18 5.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MMU163 PF17119.5 KFM81606.1 - 0.94 8.6 3.7 0.35 10.0 0.1 2.1 3 0 0 3 3 3 0 Mitochondrial protein up-regulated during meiosis HORMA PF02301.18 KFM81607.1 - 3.5e-09 36.6 0.8 6e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 HORMA domain PHD_2 PF13831.6 KFM81607.1 - 1.5e-06 27.6 1.7 1.5e-06 27.6 1.7 1.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KFM81607.1 - 4.6e-06 26.4 11.2 9.9e-06 25.4 11.2 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KFM81607.1 - 0.00065 19.6 6.8 0.00065 19.6 6.8 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 DUF2616 PF11077.8 KFM81607.1 - 0.11 12.2 6.2 0.17 11.6 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) G-alpha PF00503.20 KFM81609.1 - 1.9e-103 346.3 1.3 2.3e-103 346.1 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFM81609.1 - 2.7e-13 49.7 0.6 9.7e-09 34.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM81609.1 - 2.6e-05 23.7 1.5 0.003 16.9 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFM81609.1 - 0.00019 21.7 0.2 0.66 10.2 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFM81609.1 - 0.028 14.5 0.1 10 6.3 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KFM81609.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 KFM81609.1 - 0.068 12.8 0.7 7.4 6.1 0.1 2.6 2 1 0 2 2 2 0 Ras family Med28 PF11594.8 KFM81610.1 - 4e-11 43.1 0.8 9.1e-11 42.0 1.0 1.5 1 1 0 1 1 1 1 Mediator complex subunit 28 Spuma_A9PTase PF03539.14 KFM81610.1 - 0.0053 16.9 0.3 0.0066 16.6 0.3 1.2 1 0 0 1 1 1 1 Spumavirus aspartic protease (A9) UPF0193 PF05250.11 KFM81611.1 - 1.1e-32 113.6 5.4 1.2e-32 113.4 5.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) HSP70 PF00012.20 KFM81612.1 - 2.6e-132 442.0 2.9 2.9e-132 441.9 2.9 1.0 1 0 0 1 1 1 1 Hsp70 protein Radial_spoke_3 PF06098.11 KFM81612.1 - 0.0025 17.1 4.0 0.0043 16.4 4.0 1.3 1 0 0 1 1 1 1 Radial spoke protein 3 FGGY_C PF02782.16 KFM81612.1 - 0.063 13.0 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FKBP_N PF01346.18 KFM81612.1 - 0.62 11.1 4.9 19 6.3 0.1 2.8 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TBCA PF02970.16 KFM81612.1 - 1.1 9.7 8.5 1.8 9.0 6.6 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A HSP70 PF00012.20 KFM81613.1 - 9.7e-83 278.3 0.1 1.1e-82 278.2 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF1894 PF08979.11 KFM81613.1 - 0.063 13.7 0.0 16 5.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1894) XK-related PF09815.9 KFM81615.1 - 5.3e-07 29.0 3.9 5.3e-07 29.0 3.9 1.0 1 0 0 1 1 1 1 XK-related protein DUF3099 PF11298.8 KFM81615.1 - 1.1 9.5 5.3 0.98 9.6 4.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3099) TMEM43 PF07787.12 KFM81615.1 - 1.6 8.0 4.3 1.7 8.0 4.3 1.0 1 0 0 1 1 1 0 Transmembrane protein 43 XK-related PF09815.9 KFM81616.1 - 2.2e-06 27.0 0.2 2.6e-06 26.8 0.2 1.1 1 0 0 1 1 1 1 XK-related protein Fer2 PF00111.27 KFM81619.1 - 4.7e-08 32.9 0.2 1e-07 31.8 0.2 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 KFM81619.1 - 0.031 14.3 0.6 0.22 11.6 0.1 2.5 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain COX5B PF01215.19 KFM81620.1 - 2.7e-21 75.6 0.0 3.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb SH3_1 PF00018.28 KFM81621.1 - 7.8e-36 121.5 0.8 1.6e-16 59.6 0.1 3.3 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KFM81621.1 - 7.9e-32 108.9 0.4 6.2e-18 64.4 0.1 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KFM81621.1 - 1.2e-24 85.7 0.0 1.6e-12 46.9 0.0 2.9 3 1 0 3 3 3 2 Variant SH3 domain SH2 PF00017.24 KFM81621.1 - 2.5e-24 85.1 0.1 4.7e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 KFM81621.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH3_10 PF17902.1 KFM81621.1 - 0.0047 17.0 0.0 0.91 9.6 0.0 2.4 2 0 0 2 2 2 1 SH3 domain DUF5093 PF17011.5 KFM81621.1 - 0.058 13.7 0.1 0.12 12.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) SH3_3 PF08239.11 KFM81621.1 - 0.13 12.6 0.0 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain Diphthamide_syn PF01866.17 KFM81622.1 - 1.7e-117 392.2 0.0 2e-117 392.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Nucleopor_Nup85 PF07575.13 KFM81623.1 - 0.095 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin Nucleopor_Nup85 PF07575.13 KFM81624.1 - 4e-31 108.2 2.4 4.2e-31 108.1 2.4 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin 7tm_2 PF00002.24 KFM81625.1 - 1.6e-47 161.9 20.7 2.2e-47 161.4 20.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFM81625.1 - 1.9e-18 66.7 0.0 7.1e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain GPS PF01825.21 KFM81625.1 - 3.2e-11 43.6 1.8 3.2e-11 43.6 1.8 3.4 2 1 0 2 2 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFM81625.1 - 2.4e-09 37.3 2.2 2.4e-09 37.3 2.2 2.4 2 0 0 2 2 1 1 Hormone receptor domain Laminin_EGF PF00053.24 KFM81625.1 - 2.3e-08 34.0 11.3 2.3e-08 34.0 11.3 4.8 3 1 1 4 4 4 1 Laminin EGF domain EGF PF00008.27 KFM81625.1 - 7.6e-05 22.9 6.8 7.6e-05 22.9 6.8 4.4 4 0 0 4 4 2 2 EGF-like domain hEGF PF12661.7 KFM81625.1 - 0.0027 18.3 2.6 0.0027 18.3 2.6 5.0 4 1 0 4 4 3 1 Human growth factor-like EGF Dicty_CAR PF05462.11 KFM81625.1 - 0.037 13.2 17.5 0.064 12.4 17.5 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Laminin_G_2 PF02210.24 KFM81625.1 - 0.056 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain DUF4064 PF13273.6 KFM81625.1 - 1.7 9.0 10.8 13 6.2 4.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) SLATT_5 PF18160.1 KFM81625.1 - 4 6.7 5.1 0.35 10.2 0.2 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 ORC6 PF05460.13 KFM81625.1 - 7.9 5.6 11.1 16 4.6 11.1 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Laminin_G_2 PF02210.24 KFM81626.1 - 1.8e-18 67.3 0.0 2.1e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM81626.1 - 1.4e-12 48.0 0.0 1.7e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain MOZ_SAS PF01853.18 KFM81628.1 - 0.026 14.2 0.1 0.027 14.2 0.1 1.0 1 0 0 1 1 1 0 MOZ/SAS family ANF_receptor PF01094.28 KFM81631.1 - 1.2e-48 166.0 0.0 2.6e-45 155.1 0.0 2.4 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFM81631.1 - 1.2e-36 125.8 0.1 3.2e-36 124.4 0.1 1.8 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFM81631.1 - 5.7e-32 110.3 0.0 1.4e-31 109.0 0.0 1.7 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM81631.1 - 2.3e-19 69.7 0.0 7.9e-19 68.0 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CaM_bdg_C0 PF10562.9 KFM81631.1 - 7.4e-15 54.7 5.9 1.4e-14 53.8 5.9 1.5 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit PMP1_2 PF08114.11 KFM81631.1 - 0.035 13.8 0.3 0.097 12.4 0.3 1.7 1 0 0 1 1 1 0 ATPase proteolipid family CopD PF05425.13 KFM81631.1 - 0.83 10.1 3.6 3.3 8.2 0.5 3.0 2 1 1 3 3 3 0 Copper resistance protein D Ion_trans_2 PF07885.16 KFM81631.1 - 1.9 8.5 7.6 0.058 13.4 0.8 1.9 2 0 0 2 2 2 0 Ion channel Acyl-CoA_dh_1 PF00441.24 KFM81632.1 - 0.11 12.7 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ArdA PF07275.11 KFM81633.1 - 0.089 13.4 1.4 4.9 7.7 0.1 2.1 1 1 1 2 2 2 0 Antirestriction protein (ArdA) PSP1 PF04468.12 KFM81633.1 - 0.11 12.8 0.3 0.23 11.8 0.1 1.6 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Peptidase_M13_N PF05649.13 KFM81634.1 - 3.7e-15 56.5 0.1 4e-15 56.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M13 I-set PF07679.16 KFM81636.1 - 1.2e-91 300.9 0.1 2.3e-16 59.6 0.0 8.7 9 0 0 9 9 9 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM81636.1 - 4.4e-87 286.8 11.2 2.8e-13 50.3 0.0 9.7 10 0 0 10 10 9 7 Immunoglobulin domain Ig_2 PF13895.6 KFM81636.1 - 1.6e-58 195.0 3.9 7e-10 39.1 0.0 8.9 9 0 0 9 9 9 7 Immunoglobulin domain ig PF00047.25 KFM81636.1 - 6.9e-55 183.2 3.2 1.6e-07 31.4 0.0 8.1 8 0 0 8 8 7 7 Immunoglobulin domain fn3 PF00041.21 KFM81636.1 - 1e-31 109.1 9.0 1.9e-15 57.0 0.4 3.3 3 0 0 3 3 3 2 Fibronectin type III domain V-set PF07686.17 KFM81636.1 - 1.3e-30 105.8 15.5 0.0015 18.7 0.1 12.9 10 4 0 10 10 10 6 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM81636.1 - 7.1e-21 73.5 0.0 0.13 11.8 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain Ig_5 PF16681.5 KFM81636.1 - 2.7e-17 62.9 0.8 0.086 13.3 0.0 8.5 9 1 0 9 9 8 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFM81636.1 - 5.9e-16 58.3 3.4 0.12 12.5 0.0 7.7 7 1 1 8 8 8 3 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFM81636.1 - 6.5e-14 51.9 0.0 0.043 14.1 0.0 8.4 7 1 0 7 7 7 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM81636.1 - 2.6e-11 43.4 0.1 1.8 8.7 0.0 7.1 7 0 0 7 7 7 3 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFM81636.1 - 4.6e-10 39.7 6.7 0.054 13.9 0.0 6.0 6 0 0 6 6 5 3 Immunoglobulin C1-set domain Pur_ac_phosph_N PF16656.5 KFM81636.1 - 3.5e-09 37.1 7.8 3.9e-05 24.1 0.5 3.4 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 KFM81636.1 - 6.2e-07 29.4 0.1 3.1 7.9 0.0 6.5 8 0 0 8 8 6 1 C17orf99 Ig domain C2-set PF05790.15 KFM81636.1 - 8.7e-05 22.6 0.1 93 3.3 0.0 6.5 7 0 0 7 7 6 0 Immunoglobulin C2-set domain Tissue_fac PF01108.17 KFM81636.1 - 0.00011 22.0 0.3 0.32 10.9 0.0 2.6 2 0 0 2 2 2 2 Tissue factor DAG1 PF05454.11 KFM81636.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.6 KFM81636.1 - 0.018 14.9 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family fn3_2 PF16893.5 KFM81636.1 - 0.041 14.0 0.5 0.72 10.0 0.1 2.6 2 0 0 2 2 2 0 Fibronectin type III domain Cadherin_C_2 PF16492.5 KFM81636.1 - 0.062 14.1 0.0 0.19 12.5 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Tsg PF04668.12 KFM81640.1 - 4.2e-48 163.4 5.2 4.2e-48 163.4 5.2 2.5 2 0 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region Neurokinin_B PF03823.14 KFM81640.1 - 0.46 10.5 2.2 1.1 9.4 2.2 1.6 1 0 0 1 1 1 0 Neurokinin B zf-H2C2_2 PF13465.6 KFM81642.1 - 1.1e-67 221.6 74.7 2.1e-08 34.2 0.6 11.5 12 0 0 12 12 11 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM81642.1 - 5.6e-48 158.8 92.3 1.2e-05 25.5 5.2 11.0 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81642.1 - 5e-36 120.2 81.9 0.00036 21.1 1.6 10.9 11 0 0 11 11 11 10 C2H2-type zinc finger zf-met PF12874.7 KFM81642.1 - 3.4e-27 94.0 74.5 0.00062 20.1 1.1 11.3 11 0 0 11 11 11 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM81642.1 - 9.5e-20 70.4 53.0 0.0018 18.5 1.5 10.9 10 1 1 11 11 11 8 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM81642.1 - 3.5e-11 42.6 65.3 0.034 13.9 0.7 10.5 10 0 0 10 10 10 7 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM81642.1 - 1.2e-09 38.0 21.6 0.16 12.1 0.0 8.7 6 3 3 9 9 9 3 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 KFM81642.1 - 5.7e-09 35.8 71.7 0.052 13.6 0.3 11.8 12 0 0 12 12 11 5 C2H2-type zinc finger GAGA PF09237.11 KFM81642.1 - 1.2e-08 34.6 10.8 0.084 12.7 0.1 7.2 1 1 7 9 9 8 3 GAGA factor zf-C2H2_11 PF16622.5 KFM81642.1 - 2.5e-07 30.3 57.9 0.5 10.2 0.3 10.2 10 0 0 10 10 10 6 zinc-finger C2H2-type DUF2256 PF10013.9 KFM81642.1 - 3.2e-07 30.3 34.6 0.48 10.6 0.2 9.6 10 0 0 10 10 10 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-RRPl_C4 PF17026.5 KFM81642.1 - 4e-07 30.1 35.8 0.063 13.4 3.7 5.0 1 1 4 5 5 5 5 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 KFM81642.1 - 0.00018 21.3 49.7 0.033 14.1 5.1 8.6 1 1 8 9 9 9 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFM81642.1 - 0.00026 21.7 37.9 0.34 11.7 2.1 5.8 1 1 7 8 8 8 4 zinc-ribbon family BolA PF01722.18 KFM81642.1 - 0.0013 19.0 14.3 0.42 10.9 0.0 5.8 2 2 2 4 4 4 2 BolA-like protein YyzF PF14116.6 KFM81642.1 - 0.0022 18.0 27.6 23 5.1 0.1 9.0 9 0 0 9 9 9 0 YyzF-like protein Zf_RING PF16744.5 KFM81642.1 - 0.013 15.6 42.0 1.4 9.0 3.3 9.2 1 1 7 9 9 9 0 KIAA1045 RING finger Complex1_49kDa PF00346.19 KFM81642.1 - 0.018 14.1 6.7 0.58 9.2 0.1 3.2 1 1 2 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit A_deaminase PF00962.22 KFM81642.1 - 0.021 14.2 12.9 0.85 8.9 1.3 4.4 1 1 3 4 4 4 0 Adenosine/AMP deaminase zf-FPG_IleRS PF06827.14 KFM81642.1 - 0.025 14.4 21.0 6.7 6.7 0.1 8.4 9 0 0 9 9 9 0 Zinc finger found in FPG and IleRS zf-Dof PF02701.15 KFM81642.1 - 0.029 14.5 27.4 6.2 7.1 1.6 7.6 4 4 3 7 7 7 0 Dof domain, zinc finger DUF4712 PF15830.5 KFM81642.1 - 0.034 13.8 1.1 5.7 6.6 0.0 3.0 1 1 2 4 4 4 0 Domain of unknown function (DUF4712) TetR_C_7 PF14246.6 KFM81642.1 - 0.062 13.3 0.0 28 4.8 0.0 3.7 4 1 1 5 5 4 0 AefR-like transcriptional repressor, C-terminal domain DUF4806 PF16064.5 KFM81642.1 - 0.07 13.4 7.1 2.7 8.3 0.0 4.5 2 2 3 5 5 5 0 Domain of unknown function (DUF4806) DUF2992 PF11208.8 KFM81642.1 - 0.094 13.0 1.0 4.1 7.7 0.1 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF2992) TRAF6_Z2 PF18048.1 KFM81642.1 - 0.18 12.0 44.9 0.32 11.1 3.4 8.9 9 0 0 9 9 9 0 TNF receptor-associated factor 6 zinc finger 2 Zn_ribbon_SprT PF17283.2 KFM81642.1 - 0.24 11.3 20.1 1.1 9.3 0.7 6.7 6 2 1 7 7 7 0 SprT-like zinc ribbon domain zf-MYST PF17772.1 KFM81642.1 - 0.45 10.2 43.0 4 7.1 0.1 9.3 6 3 4 10 10 10 0 MYST family zinc finger domain zf-C2HC_2 PF13913.6 KFM81642.1 - 0.46 10.4 0.1 0.46 10.4 0.1 8.9 10 0 0 10 10 10 0 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFM81642.1 - 1.2 9.2 35.0 1.9 8.5 1.5 5.7 5 0 0 5 5 5 0 Adenylate kinase, active site lid FYVE PF01363.21 KFM81642.1 - 1.4 9.2 46.6 1.6 8.9 2.1 5.7 1 1 2 3 3 2 0 FYVE zinc finger zf-DBF PF07535.12 KFM81642.1 - 1.6 8.9 41.0 12 6.1 0.4 9.0 10 0 0 10 10 10 0 DBF zinc finger Ribosomal_S6 PF01250.17 KFM81644.1 - 7.6e-09 35.7 0.0 8.1e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 CH PF00307.31 KFM81645.1 - 4.9e-23 81.4 0.2 6.1e-23 81.1 0.2 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM81645.1 - 1.2e-06 28.3 0.0 2e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.11 KFM81645.1 - 0.00051 20.2 0.2 0.00081 19.6 0.2 1.2 1 0 0 1 1 1 1 CDC24 Calponin Melibiase_C PF17801.1 KFM81645.1 - 0.016 15.3 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha galactosidase C-terminal beta sandwich domain Radial_spoke PF04712.12 KFM81649.1 - 0.09 11.7 2.0 0.091 11.7 2.0 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein CBM_21 PF03370.13 KFM81650.1 - 1.1e-26 93.2 0.1 1.6e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFM81650.1 - 3.1e-10 40.5 0.0 5.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) zf-C2H2 PF00096.26 KFM81652.1 - 3.3e-35 118.6 98.0 3.6e-05 24.0 0.8 12.9 13 0 0 13 13 13 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81652.1 - 1.4e-28 97.0 88.8 0.0016 19.1 0.9 12.8 12 0 0 12 12 12 11 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM81652.1 - 1e-20 73.2 97.2 1.8e-08 34.4 0.1 13.3 14 0 0 14 14 14 7 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFM81652.1 - 3.3e-06 27.0 73.1 4.1e-05 23.5 1.6 11.3 11 0 0 11 11 11 6 C2H2-type zinc finger BolA PF01722.18 KFM81652.1 - 3.9e-05 23.9 2.5 0.9 9.9 0.1 4.1 2 1 0 2 2 2 2 BolA-like protein zf-met PF12874.7 KFM81652.1 - 0.00025 21.3 55.0 0.029 14.8 0.4 10.4 11 0 0 11 11 11 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM81652.1 - 0.00028 21.1 66.6 0.0039 17.4 0.1 11.7 12 0 0 12 12 12 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM81652.1 - 0.00046 20.5 57.8 0.13 12.6 0.3 9.5 3 2 4 9 9 9 3 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFM81652.1 - 0.0014 19.0 65.7 0.03 14.8 0.1 10.3 7 2 2 9 9 8 5 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KFM81652.1 - 0.0018 18.0 39.8 0.16 11.8 0.3 8.8 9 0 0 9 9 9 3 zinc-finger C2H2-type zf_UBZ PF18439.1 KFM81652.1 - 1.9 8.1 32.9 0.34 10.5 0.1 8.2 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KFM81652.1 - 2.8 7.8 12.9 15 5.5 0.4 4.8 4 1 2 6 6 6 0 GAGA factor MFS_2 PF13347.6 KFM81653.1 - 0.06 11.9 9.4 0.077 11.5 9.4 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein Ax_dynein_light PF10211.9 KFM81654.1 - 0.032 14.2 0.4 0.037 14.0 0.4 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain MATH PF00917.26 KFM81655.1 - 0.00039 20.5 1.0 0.059 13.5 0.3 3.0 3 0 0 3 3 3 2 MATH domain Ion_trans PF00520.31 KFM81657.1 - 8.4e-30 103.8 9.0 8.4e-30 103.8 9.0 1.8 2 0 0 2 2 2 1 Ion transport protein TRP_2 PF08344.11 KFM81657.1 - 4.7e-28 97.2 0.2 1.1e-27 96.0 0.2 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 KFM81657.1 - 1.1e-10 42.0 0.3 4.5e-08 33.6 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM81657.1 - 3.1e-08 33.2 0.3 0.83 10.4 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KFM81657.1 - 3.1e-06 27.6 0.2 0.015 15.9 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 KFM81657.1 - 4.7e-05 22.3 4.7 0.012 14.4 0.7 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ank PF00023.30 KFM81657.1 - 0.0015 18.9 0.2 8.3 7.1 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFM81657.1 - 0.014 15.7 0.4 5.5 7.4 0.1 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Pkinase PF00069.25 KFM81660.1 - 3.1e-06 26.8 0.0 6.3e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain SHNi-TPR PF10516.9 KFM81661.1 - 0.014 14.8 0.0 0.04 13.4 0.0 1.8 1 0 0 1 1 1 0 SHNi-TPR Imm26 PF15428.6 KFM81661.1 - 0.077 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 26 UN_NPL4 PF11543.8 KFM81661.1 - 0.12 12.9 0.0 0.42 11.1 0.0 1.9 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Asp5 PF17000.5 KFM81661.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 TUDOR PF00567.24 KFM81662.1 - 1.1e-19 70.7 0.9 2.4e-19 69.5 0.9 1.6 1 0 0 1 1 1 1 Tudor domain RRM_1 PF00076.22 KFM81662.1 - 3.9e-09 36.2 0.1 1.7e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN PF06003.12 KFM81662.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 2.0 3 0 0 3 3 3 1 Survival motor neuron protein (SMN) RRM_7 PF16367.5 KFM81662.1 - 0.045 13.9 0.1 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif Tudor_2 PF18104.1 KFM81662.1 - 0.16 11.7 1.4 5.3 6.8 0.1 2.7 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain zf-C2H2 PF00096.26 KFM81663.1 - 1.5e-40 135.4 55.9 3.9e-05 23.9 3.0 9.1 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM81663.1 - 5.8e-33 111.9 52.3 1.4e-05 25.2 0.1 9.2 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM81663.1 - 2.3e-32 108.9 54.0 0.0026 18.5 1.8 9.2 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM81663.1 - 3e-18 65.6 48.9 0.0012 19.1 0.5 9.0 9 0 0 9 9 9 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM81663.1 - 1.8e-16 59.9 45.6 0.017 15.5 0.1 9.1 9 0 0 9 9 9 6 Zinc-finger of C2H2 type BolA PF01722.18 KFM81663.1 - 7.1e-10 39.0 6.7 0.18 12.1 0.1 6.7 2 2 5 7 7 7 2 BolA-like protein zf-MYST PF17772.1 KFM81663.1 - 2.3e-08 33.5 27.7 0.018 14.6 0.0 7.8 5 2 3 8 8 8 2 MYST family zinc finger domain zf-H2C2_5 PF13909.6 KFM81663.1 - 9.9e-05 22.0 28.9 0.71 9.7 0.4 6.7 7 0 0 7 7 6 4 C2H2-type zinc-finger domain Proteasome PF00227.26 KFM81663.1 - 0.0033 17.0 0.0 1.5 8.2 0.0 3.4 1 1 2 4 4 4 1 Proteasome subunit DUF2256 PF10013.9 KFM81663.1 - 0.0097 16.0 24.0 18 5.5 0.1 8.3 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 KFM81663.1 - 0.0097 15.7 23.3 0.9 9.4 0.3 6.2 5 2 2 7 7 7 3 GAGA factor Cript PF10235.9 KFM81663.1 - 0.017 15.7 32.7 0.13 12.8 0.9 5.0 2 2 2 4 4 4 0 Microtubule-associated protein CRIPT zf-C2H2_6 PF13912.6 KFM81663.1 - 0.039 14.0 45.8 2.1 8.4 1.5 8.4 8 0 0 8 8 8 0 C2H2-type zinc finger Copper-fist PF00649.18 KFM81663.1 - 1 8.9 17.1 11 5.5 0.1 5.9 6 0 0 6 6 6 0 Copper fist DNA binding domain zf-BED PF02892.15 KFM81663.1 - 1.2 9.2 49.7 3.3 7.8 2.5 8.4 2 2 6 8 8 8 0 BED zinc finger Ndufs5 PF10200.9 KFM81663.1 - 1.7 9.0 9.1 0.95 9.8 1.0 2.8 1 1 2 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Vps36-NZF-N PF16988.5 KFM81663.1 - 2.7 7.5 17.6 15 5.1 0.1 5.2 4 1 2 6 6 6 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF5402 PF17393.2 KFM81663.1 - 2.7 7.9 10.4 4.3 7.3 0.1 4.6 5 1 1 6 6 6 0 Family of unknown function (DUF5402) ODR4-like PF14778.6 KFM81664.1 - 8.6e-100 334.3 0.0 1e-99 334.0 0.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 4-like Na_sulph_symp PF00939.19 KFM81665.1 - 1.1e-45 156.6 13.3 4.5e-44 151.3 13.3 2.0 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFM81665.1 - 7.1e-15 55.0 4.6 1e-14 54.5 4.6 1.3 1 0 0 1 1 1 1 Citrate transporter zf-LITAF-like PF10601.9 KFM81665.1 - 2.2 8.6 5.5 6.6 7.1 0.0 3.5 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain Na_sulph_symp PF00939.19 KFM81666.1 - 1.6e-63 215.5 12.8 2.8e-63 214.6 12.8 1.4 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFM81666.1 - 1e-26 93.9 15.1 4e-21 75.5 3.0 3.1 2 1 1 3 3 3 3 Citrate transporter Sulfatase PF00884.23 KFM81667.1 - 4.1e-06 26.4 0.5 4.2e-06 26.4 0.5 1.0 1 0 0 1 1 1 1 Sulfatase Abhydrolase_1 PF00561.20 KFM81668.1 - 4.6e-15 55.9 0.0 8.6e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM81668.1 - 3.1e-14 54.1 0.0 3.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM81668.1 - 3.9e-11 42.7 0.0 5.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFM81668.1 - 6.7e-06 26.0 0.0 8e-05 22.5 0.0 2.0 1 1 1 2 2 2 1 PGAP1-like protein Esterase PF00756.20 KFM81668.1 - 0.00073 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.14 KFM81668.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.11 KFM81668.1 - 0.024 14.0 0.2 2.2 7.5 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2573 PF10835.8 KFM81668.1 - 0.071 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) Lipase_3 PF01764.25 KFM81668.1 - 0.12 12.3 0.1 0.44 10.4 0.0 1.7 2 1 0 2 2 2 0 Lipase (class 3) Ndr PF03096.14 KFM81668.1 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 KFM81669.1 - 6.6e-18 65.3 0.0 4.4e-16 59.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM81669.1 - 1.2e-10 42.4 0.0 6e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM81669.1 - 2.7e-06 26.8 0.0 4.8e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFM81669.1 - 4e-05 23.4 0.0 0.0037 17.0 0.0 2.2 1 1 1 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 KFM81669.1 - 0.00047 19.7 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_2 PF01674.18 KFM81669.1 - 0.00048 19.7 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 2) Palm_thioest PF02089.15 KFM81669.1 - 0.0025 17.7 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Esterase PF00756.20 KFM81669.1 - 0.0037 17.0 0.0 0.0093 15.6 0.0 1.6 1 1 1 2 2 2 1 Putative esterase Chlorophyllase2 PF12740.7 KFM81669.1 - 0.0063 15.5 0.0 0.054 12.4 0.0 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFM81669.1 - 0.021 13.8 0.1 0.077 12.0 0.1 1.8 1 1 0 1 1 1 0 Chlorophyllase DUF915 PF06028.11 KFM81669.1 - 0.027 13.8 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Spc7 PF08317.11 KFM81670.1 - 3.2 6.6 43.6 0.028 13.3 14.7 3.8 2 1 2 4 4 4 0 Spc7 kinetochore protein ATG16 PF08614.11 KFM81670.1 - 3.2 7.9 48.9 0.074 13.3 15.8 3.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Hemerythrin PF01814.23 KFM81670.1 - 7 7.3 8.1 0.91 10.1 1.0 2.8 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Pox_Ag35 PF03286.14 KFM81671.1 - 0.94 9.2 8.7 1.3 8.8 2.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KFM81671.1 - 2.2 7.5 6.0 4.8 6.4 6.0 1.5 1 0 0 1 1 1 0 NOA36 protein SPRY PF00622.28 KFM81673.1 - 1.6e-17 63.8 0.1 3.7e-17 62.6 0.0 1.6 2 0 0 2 2 2 1 SPRY domain Dynein_light PF01221.18 KFM81674.1 - 1.9e-32 111.4 1.0 2.1e-32 111.3 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 KFM81674.1 - 0.036 13.5 0.0 0.036 13.5 0.0 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin DUF4901 PF16244.5 KFM81674.1 - 0.055 12.8 1.0 0.059 12.7 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) Ectatomin PF06457.11 KFM81674.1 - 0.2 11.6 0.3 0.2 11.6 0.3 1.6 2 0 0 2 2 2 0 Ectatomin Ubie_methyltran PF01209.18 KFM81675.1 - 6.6e-85 284.1 0.0 8.7e-85 283.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KFM81675.1 - 3.9e-16 59.5 0.0 9.2e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM81675.1 - 2.4e-15 57.0 0.0 5e-14 52.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM81675.1 - 4.2e-12 46.1 0.0 1.3e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM81675.1 - 3.3e-07 31.0 0.0 8.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM81675.1 - 3.8e-05 23.6 0.0 6.2e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KFM81675.1 - 0.0015 18.3 0.0 0.0037 17.0 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_29 PF03141.16 KFM81675.1 - 0.019 13.6 0.0 0.033 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MlaA PF04333.13 KFM81675.1 - 0.048 13.3 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 MlaA lipoprotein SCP-1 PF05483.12 KFM81676.1 - 5.9e-08 31.2 4.1 6.5e-08 31.1 4.1 1.0 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) UPF0242 PF06785.11 KFM81676.1 - 0.0091 16.1 5.6 0.01 16.0 5.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus 7TMR-HDED PF07697.11 KFM81676.1 - 0.013 15.6 2.0 0.015 15.4 2.0 1.1 1 0 0 1 1 1 0 7TM-HD extracellular ADIP PF11559.8 KFM81676.1 - 0.12 12.5 9.4 0.15 12.2 9.4 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 KFM81676.1 - 0.15 11.1 6.9 0.19 10.8 6.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KFM81676.1 - 2.1 7.5 6.9 2.6 7.2 6.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 KFM81676.1 - 3.2 8.4 8.5 8 7.2 6.1 2.1 1 1 1 2 2 2 0 SlyX APG6_N PF17675.1 KFM81677.1 - 0.022 15.3 3.4 0.024 15.1 3.4 1.0 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4885 PF16226.5 KFM81677.1 - 0.12 11.4 0.8 0.11 11.5 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) Tropomyosin_1 PF12718.7 KFM81678.1 - 0.014 15.6 26.4 0.14 12.3 17.1 3.2 1 1 1 2 2 2 0 Tropomyosin like CorA PF01544.18 KFM81678.1 - 0.25 10.6 7.6 0.28 10.4 7.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Rootletin PF15035.6 KFM81678.1 - 0.5 10.4 14.9 0.96 9.4 6.5 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Shugoshin_N PF07558.11 KFM81678.1 - 1.3 9.0 17.3 3.1 7.7 0.2 4.5 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region AAA_11 PF13086.6 KFM81678.1 - 2.3 8.0 8.9 2.9 7.6 8.9 1.1 1 0 0 1 1 1 0 AAA domain Med9 PF07544.13 KFM81678.1 - 2.5 8.2 20.5 16 5.7 3.5 3.7 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Rho_Binding PF08912.11 KFM81678.1 - 3 8.7 27.0 5.2 8.0 8.1 3.0 1 1 2 3 3 3 0 Rho Binding DUF1664 PF07889.12 KFM81678.1 - 4.1 7.5 12.8 5 7.2 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 KFM81678.1 - 9.7 6.8 13.0 9.3 6.9 3.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HALZ PF02183.18 KFM81679.1 - 0.021 15.0 24.6 0.47 10.7 1.7 4.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper HARP PF07443.13 KFM81679.1 - 0.08 12.6 2.3 5.6 6.7 0.1 3.6 1 1 2 3 3 3 0 HepA-related protein (HARP) Rx_N PF18052.1 KFM81679.1 - 0.18 12.1 17.6 0.23 11.7 3.5 3.8 1 1 1 3 3 3 0 Rx N-terminal domain Spc7 PF08317.11 KFM81679.1 - 0.33 9.8 36.4 0.88 8.4 13.0 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 KFM81679.1 - 0.99 10.1 20.6 2.7 8.7 0.9 5.0 2 1 3 5 5 5 0 SlyX PRKG1_interact PF15898.5 KFM81679.1 - 4.3 8.3 41.3 0.63 11.0 14.4 4.3 2 2 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF4042 PF13251.6 KFM81680.1 - 1e-54 185.0 5.5 4.9e-52 176.3 2.4 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4042) HEAT PF02985.22 KFM81680.1 - 1.2e-19 68.7 11.5 0.00052 20.1 0.0 9.6 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 KFM81680.1 - 2.5e-13 50.2 0.0 0.0005 20.4 0.0 5.3 4 2 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 KFM81680.1 - 1.5e-11 44.5 1.3 0.13 12.8 0.0 6.4 5 2 1 6 6 6 3 HEAT-like repeat Cnd1 PF12717.7 KFM81680.1 - 3.7e-05 23.8 6.5 0.67 10.0 0.0 4.4 3 2 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KFM81680.1 - 0.0051 16.0 10.9 0.0058 15.9 0.1 3.8 4 1 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KFM81680.1 - 0.0071 16.3 15.3 1.4 9.0 0.0 6.7 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat UPF0767 PF15990.5 KFM81682.1 - 5.7e-28 96.9 0.0 6.3e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 UPF0767 family DHR10 PF18595.1 KFM81682.1 - 0.0092 16.0 0.5 0.011 15.8 0.5 1.1 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Phage_holin_5_2 PF16079.5 KFM81682.1 - 0.039 14.3 0.2 0.049 14.0 0.2 1.2 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V BRX_N PF13713.6 KFM81682.1 - 0.067 13.0 0.1 0.092 12.5 0.1 1.2 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Mito_carr PF00153.27 KFM81683.1 - 7.4e-60 198.9 3.9 1.9e-20 72.5 0.0 3.7 2 2 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM81683.1 - 0.005 16.0 0.1 0.014 14.6 0.0 1.8 2 0 0 2 2 2 1 Gammaproteobacterial serine protease GTP_EFTU PF00009.27 KFM81685.1 - 2e-65 220.0 0.1 2.8e-65 219.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFM81685.1 - 4.4e-33 113.6 0.0 9.8e-33 112.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KFM81685.1 - 2.5e-17 62.7 0.0 5.5e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFM81685.1 - 3.5e-13 49.7 0.1 1.2e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFM81685.1 - 6.7e-13 48.5 0.0 1.9e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KFM81685.1 - 0.00034 20.7 0.1 0.0008 19.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Elongin_A PF06881.11 KFM81685.1 - 0.031 14.8 0.1 6.3 7.4 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TetR_C_25 PF17933.1 KFM81685.1 - 0.06 13.7 0.0 0.29 11.5 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FAST_1 PF06743.15 KFM81685.1 - 0.12 12.3 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 RsgA_GTPase PF03193.16 KFM81685.1 - 0.13 12.1 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase HTH_Crp_2 PF13545.6 KFM81686.1 - 0.042 13.8 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain SLAM PF06214.11 KFM81686.1 - 0.17 11.9 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein TerY_C PF15616.6 KFM81687.1 - 0.029 14.5 0.2 0.043 13.9 0.2 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain EST1_DNA_bind PF10373.9 KFM81688.1 - 1.6e-05 24.5 1.0 1.7e-05 24.5 1.0 1.0 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1_DNA_bind PF10373.9 KFM81690.1 - 4.9e-20 72.2 2.3 5.3e-20 72.0 1.3 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KFM81690.1 - 2.4e-17 63.8 4.4 8.3e-17 62.1 1.9 2.3 2 0 0 2 2 2 1 Telomerase activating protein Est1 ArsA_ATPase PF02374.15 KFM81691.1 - 5.4e-112 373.9 0.0 6.3e-112 373.7 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KFM81691.1 - 1.1e-09 38.5 0.1 4.4e-09 36.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KFM81691.1 - 1.4e-08 34.9 0.1 5.1e-08 33.0 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KFM81691.1 - 2.7e-05 23.8 0.0 5.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 KFM81691.1 - 8.8e-05 22.1 0.1 0.0003 20.3 0.1 1.8 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KFM81691.1 - 0.00035 20.1 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KFM81691.1 - 0.002 17.8 0.0 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KFM81691.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 KFM81691.1 - 0.026 14.0 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 KFM81691.1 - 0.029 13.6 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.6 KFM81691.1 - 0.035 14.2 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Elf1 PF05129.13 KFM81691.1 - 0.09 12.8 0.3 0.54 10.3 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like AAA_25 PF13481.6 KFM81691.1 - 0.092 12.3 0.3 0.27 10.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KFM81691.1 - 0.097 11.6 0.1 0.5 9.3 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KFM81691.1 - 0.18 12.3 0.0 0.27 11.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Ribosomal_L38e PF01781.18 KFM81692.1 - 1.4e-36 124.4 3.0 1.5e-36 124.3 3.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family HEAT PF02985.22 KFM81693.1 - 0.041 14.1 0.4 0.24 11.8 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat IBN_N PF03810.19 KFM81694.1 - 4.1e-16 58.6 0.4 3.2e-14 52.6 0.2 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFM81694.1 - 0.004 17.2 0.8 0.004 17.2 0.8 2.5 3 0 0 3 3 3 1 Exportin 1-like protein Phage_CI_repr PF07022.13 KFM81694.1 - 0.057 13.5 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HEAT PF02985.22 KFM81694.1 - 0.06 13.6 0.4 0.36 11.2 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 KFM81694.1 - 0.072 13.5 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats ELL PF10390.9 KFM81695.1 - 4.7e-13 49.3 0.1 5e-13 49.2 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL TRI12 PF06609.13 KFM81696.1 - 0.16 10.3 1.9 0.16 10.4 1.9 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) EB PF01683.18 KFM81697.1 - 0.00067 19.9 0.4 0.00079 19.7 0.4 1.1 1 0 0 1 1 1 1 EB module VWD PF00094.25 KFM81699.1 - 4e-34 118.2 0.7 4e-34 118.2 0.7 2.0 3 0 0 3 3 3 1 von Willebrand factor type D domain C8 PF08742.11 KFM81699.1 - 9e-19 67.7 9.7 9e-19 67.7 9.7 4.2 4 1 2 6 6 6 1 C8 domain VWC PF00093.18 KFM81699.1 - 1.7e-18 66.7 38.7 1e-12 48.2 16.4 5.7 4 1 0 4 4 4 3 von Willebrand factor type C domain TIL PF01826.17 KFM81699.1 - 3.4e-09 36.8 13.6 3.4e-09 36.8 13.6 6.4 3 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 KFM81699.1 - 2.4e-05 24.2 25.1 0.0009 19.2 9.1 4.9 4 1 0 4 4 4 2 TILa domain VWC PF00093.18 KFM81700.1 - 2e-12 47.2 37.7 3.5e-07 30.4 14.3 2.2 2 0 0 2 2 2 2 von Willebrand factor type C domain Vac14_Fab1_bd PF12755.7 KFM81700.1 - 0.041 14.5 0.0 0.06 14.0 0.0 1.1 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region TILa PF12714.7 KFM81700.1 - 0.66 10.0 35.5 0.11 12.5 10.7 2.7 2 1 0 2 2 2 0 TILa domain VWC PF00093.18 KFM81701.1 - 1.7e-50 169.1 206.6 2.1e-07 31.1 12.9 9.5 10 0 0 10 10 10 9 von Willebrand factor type C domain VWC PF00093.18 KFM81702.1 - 3e-53 178.0 168.3 3.1e-09 37.0 18.5 8.1 8 0 0 8 8 8 8 von Willebrand factor type C domain TILa PF12714.7 KFM81702.1 - 1.6e-10 40.8 139.3 2.1e-06 27.6 7.5 9.0 5 3 2 9 9 9 7 TILa domain VWC PF00093.18 KFM81703.1 - 1.7e-10 41.0 14.5 2.3e-10 40.6 14.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type C domain TILa PF12714.7 KFM81703.1 - 2.1e-07 30.8 4.5 2.1e-07 30.8 4.5 1.9 1 1 0 2 2 2 1 TILa domain Phosducin PF02114.16 KFM81703.1 - 0.12 11.3 1.5 0.13 11.2 1.5 1.1 1 0 0 1 1 1 0 Phosducin Tyrosinase PF00264.20 KFM81705.1 - 1.5e-13 51.6 0.9 1.9e-13 51.2 0.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase EGF PF00008.27 KFM81706.1 - 2.8e-06 27.5 6.4 2.8e-06 27.5 6.4 2.5 2 1 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 KFM81706.1 - 0.016 15.6 6.3 0.16 12.4 6.3 2.7 1 1 0 1 1 1 0 EGF-like domain hEGF PF12661.7 KFM81706.1 - 6.5 7.6 11.3 0.22 12.2 2.6 3.1 3 1 0 3 3 3 0 Human growth factor-like EGF Tyrosinase PF00264.20 KFM81707.1 - 1.1e-16 61.9 3.5 1.2e-13 51.8 3.5 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase Aminotran_3 PF00202.21 KFM81710.1 - 9.9e-94 314.3 0.0 1.5e-93 313.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III MtaB PF12176.8 KFM81711.1 - 0.0027 16.6 1.0 0.004 16.0 1.0 1.3 1 1 0 1 1 1 1 Methanol-cobalamin methyltransferase B subunit TFIIS_C PF01096.18 KFM81711.1 - 0.047 13.6 2.4 0.65 9.9 0.6 3.0 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-H2C2_2 PF13465.6 KFM81712.1 - 2.7e-09 37.0 23.3 0.0012 19.2 8.0 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM81712.1 - 1.5e-08 34.8 21.9 0.00035 21.2 3.1 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM81712.1 - 1.7e-08 34.5 24.7 0.00015 22.1 4.6 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.7 KFM81712.1 - 0.00017 21.9 1.8 0.00017 21.9 1.8 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM81712.1 - 0.0004 20.6 1.5 0.0004 20.6 1.5 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM81712.1 - 0.0012 18.5 6.4 0.0012 18.5 6.4 3.9 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM81712.1 - 0.0057 16.6 2.9 0.0057 16.6 2.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger Rep_fac-A_C PF08646.10 KFM81712.1 - 0.27 11.0 8.5 0.22 11.2 3.8 2.1 1 1 1 2 2 2 0 Replication factor-A C terminal domain zf-Sec23_Sec24 PF04810.15 KFM81712.1 - 0.29 11.2 8.4 1.3 9.1 0.4 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Ta0938 PF11494.8 KFM81712.1 - 0.32 11.3 3.3 1 9.6 0.2 2.2 1 1 1 2 2 2 0 Ta0938 zf-C2HC_2 PF13913.6 KFM81712.1 - 0.77 9.7 0.2 0.77 9.7 0.2 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFM81712.1 - 1.3 8.8 0.0 1.3 8.8 0.0 3.3 3 1 0 3 3 2 0 zinc-finger C2H2-type CpXC PF14353.6 KFM81712.1 - 2.8 8.0 7.6 7.7 6.6 0.1 2.8 1 1 2 3 3 3 0 CpXC protein zf-MYST PF17772.1 KFM81712.1 - 3.4 7.3 12.2 12 5.6 1.5 3.0 2 1 1 3 3 3 0 MYST family zinc finger domain HypA PF01155.19 KFM81712.1 - 5.1 7.1 7.0 36 4.4 7.0 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 KFM81712.1 - 7.1 6.9 18.2 6.7 7.0 0.5 3.3 1 1 1 2 2 2 0 AN1-like Zinc finger zf-H2C2_2 PF13465.6 KFM81713.1 - 1.4e-06 28.4 5.0 2.8e-05 24.3 1.2 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM81713.1 - 1.4e-05 25.2 1.8 1.9e-05 24.8 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81713.1 - 4.2e-05 24.0 1.0 5.5e-05 23.7 1.0 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM81713.1 - 0.00025 20.7 1.5 0.00025 20.7 1.5 1.9 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM81713.1 - 0.00095 18.9 0.4 0.0012 18.6 0.4 1.2 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM81713.1 - 0.0032 17.4 0.5 0.0052 16.8 0.5 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger BolA PF01722.18 KFM81713.1 - 0.01 16.1 0.0 0.012 15.9 0.0 1.0 1 0 0 1 1 1 0 BolA-like protein zf-C2HE PF16278.5 KFM81713.1 - 0.022 15.2 0.6 0.022 15.2 0.6 1.1 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 KFM81713.1 - 0.034 13.9 0.1 0.039 13.7 0.1 1.1 1 0 0 1 1 1 0 GAGA factor zf-H2C2_2 PF13465.6 KFM81714.1 - 7.4e-16 57.8 11.9 3.3e-09 36.8 0.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM81714.1 - 2.7e-10 40.1 13.5 3.2e-05 24.1 3.9 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81714.1 - 3.9e-07 30.3 11.2 0.0013 19.4 1.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM81714.1 - 1.8e-06 28.1 8.0 0.0034 17.6 2.7 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM81714.1 - 3.3e-06 27.0 10.2 0.0066 16.4 1.4 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM81714.1 - 4.3e-06 26.9 10.9 0.009 16.4 3.7 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type BolA PF01722.18 KFM81714.1 - 0.00036 20.8 0.2 0.086 13.1 0.0 2.0 1 1 1 2 2 2 2 BolA-like protein zf-MYST PF17772.1 KFM81714.1 - 0.00089 18.8 4.1 0.00094 18.7 0.3 2.0 1 1 1 2 2 2 1 MYST family zinc finger domain zf-C2H2_11 PF16622.5 KFM81714.1 - 0.0023 17.7 6.8 0.014 15.1 0.8 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type Zf_RING PF16744.5 KFM81714.1 - 0.023 14.8 3.1 0.31 11.2 0.4 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KFM81714.1 - 0.42 11.0 6.8 1.3 9.4 2.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFM81714.1 - 1.4 9.5 7.3 4.2 7.9 1.4 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KFM81714.1 - 3.2 7.6 12.9 0.69 9.7 0.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Cas_DxTHG PF09455.10 KFM81715.1 - 0.047 13.3 0.0 0.047 13.3 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family SNF2_N PF00176.23 KFM81716.1 - 1.2e-61 208.4 0.0 1.2e-61 208.4 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 KFM81716.1 - 6.2e-07 29.6 2.9 1.5e-05 25.1 0.0 3.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit TagA PF12561.8 KFM81716.1 - 0.87 10.0 3.4 15 6.1 0.1 2.6 1 1 0 2 2 2 0 ToxR activated gene A lipoprotein domain Helicase_C PF00271.31 KFM81717.1 - 1.2e-21 77.1 0.1 3.6e-21 75.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFM81717.1 - 2.6e-05 23.5 0.8 6.5e-05 22.2 0.8 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KFM81717.1 - 7.1e-05 22.1 0.1 0.00012 21.4 0.0 1.3 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase MFS_1 PF07690.16 KFM81718.1 - 9.9e-15 54.3 19.0 1.1e-13 50.9 13.5 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFM81719.1 - 1e-07 31.2 5.5 1.2e-07 31.0 5.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4013 PF13197.6 KFM81719.1 - 0.042 13.7 3.5 0.05 13.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) NDUF_B12 PF08122.12 KFM81719.1 - 0.11 12.6 0.5 0.29 11.2 0.2 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family MFS_1 PF07690.16 KFM81720.1 - 2.7e-11 43.0 18.3 4.4e-11 42.3 18.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFM81721.1 - 6.6e-19 68.0 14.7 8.4e-19 67.7 14.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TGF_beta PF00019.20 KFM81723.1 - 2.2e-29 102.5 0.2 5.3e-29 101.3 0.2 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFM81723.1 - 3.9e-09 36.6 3.2 5.6e-08 32.8 3.2 2.0 1 1 0 1 1 1 1 TGF-beta propeptide 7tm_2 PF00002.24 KFM81725.1 - 1.5e-22 80.1 20.2 2.5e-22 79.4 20.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 KFM81726.1 - 0.00092 19.6 7.1 0.005 17.2 7.1 2.3 1 0 0 1 1 1 1 Somatomedin B domain CHGN PF05679.16 KFM81727.1 - 2.2e-88 297.3 0.0 2.9e-88 297.0 0.0 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFM81727.1 - 4.1e-10 39.2 1.1 9e-10 38.1 1.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFM81727.1 - 0.03 13.8 0.2 0.52 9.7 0.2 2.1 1 1 0 1 1 1 0 Glycosyltransferase like family 2 CCDC92 PF14916.6 KFM81727.1 - 0.034 13.9 0.2 0.098 12.4 0.2 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function DUF4094 PF13334.6 KFM81727.1 - 0.12 12.9 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Csm1_N PF18504.1 KFM81727.1 - 0.13 12.6 0.9 0.28 11.5 0.3 1.8 2 0 0 2 2 2 0 Csm1 N-terminal domain PP1_inhibitor PF05361.12 KFM81728.1 - 1.4e-11 44.5 1.2 1.6e-11 44.4 1.2 1.1 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor NUFIP1 PF10453.9 KFM81728.1 - 0.063 13.1 0.5 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF4793 PF16041.5 KFM81729.1 - 3.5e-12 46.4 0.3 8.1e-12 45.3 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) DUF4792 PF16040.5 KFM81729.1 - 4.9e-09 36.0 1.7 5.5e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4792) DUF4634 PF15465.6 KFM81729.1 - 0.29 11.4 3.4 0.32 11.3 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4634) DUF4793 PF16041.5 KFM81730.1 - 7.5e-17 61.5 0.0 1.3e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) DUF4792 PF16040.5 KFM81730.1 - 0.0031 17.4 0.0 0.01 15.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4792) DMAP_binding PF06464.11 KFM81731.1 - 0.012 16.4 2.4 2.2 9.1 0.0 3.3 3 1 0 3 3 3 0 DMAP1-binding Domain SesA PF17107.5 KFM81731.1 - 0.029 14.6 0.8 0.11 12.7 0.2 1.9 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases UPF0147 PF03685.13 KFM81731.1 - 0.088 12.9 1.7 10 6.3 0.0 2.9 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0147) DUF4460 PF14687.6 KFM81731.1 - 0.091 12.8 0.6 4.9 7.3 0.0 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4460) SEO_N PF14576.6 KFM81731.1 - 0.1 11.7 0.5 0.14 11.3 0.4 1.2 1 1 0 1 1 1 0 Sieve element occlusion N-terminus Latarcin PF10279.9 KFM81731.1 - 0.11 12.9 1.5 0.25 11.8 1.3 1.9 1 1 0 1 1 1 0 Latarcin precursor YppF PF14178.6 KFM81734.1 - 0.025 14.5 0.4 0.032 14.1 0.4 1.2 1 0 0 1 1 1 0 YppF-like protein ER PF01133.17 KFM81736.1 - 8.2e-43 144.4 0.1 9e-43 144.3 0.1 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Ion_trans PF00520.31 KFM81737.1 - 3.1e-45 154.3 58.8 3.5e-30 105.0 32.1 2.2 2 0 0 2 2 2 2 Ion transport protein CoA_binding_3 PF13727.6 KFM81737.1 - 0.02 14.9 1.5 0.53 10.3 0.1 2.8 2 0 0 2 2 2 0 CoA-binding domain ATP-synt_8 PF00895.20 KFM81737.1 - 0.5 10.9 6.4 2.2 8.8 0.0 3.9 3 0 0 3 3 3 0 ATP synthase protein 8 PKD_channel PF08016.12 KFM81737.1 - 5.9 5.4 41.2 2 7.0 8.3 4.2 2 1 1 3 3 3 0 Polycystin cation channel DUF4495 PF14906.6 KFM81738.1 - 9.6e-40 136.6 6.1 1.1e-39 136.4 6.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4495) BLOC1S3 PF15753.5 KFM81739.1 - 0.073 13.2 0.2 0.09 12.9 0.2 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 COMM_domain PF07258.14 KFM81740.1 - 5.1e-13 48.9 0.4 5.1e-13 48.9 0.4 2.3 2 0 0 2 2 2 1 COMM domain Transposase_1 PF01359.18 KFM81741.1 - 5.8e-10 38.9 0.0 8.6e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM81741.1 - 1.9e-08 34.2 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 KFM81741.1 - 0.036 14.2 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain PIN_10 PF18478.1 KFM81741.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 PIN like domain Arf PF00025.21 KFM81743.1 - 9.1e-07 28.5 0.0 9.7e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRP54 PF00448.22 KFM81743.1 - 0.057 13.1 0.1 0.064 12.9 0.1 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KFM81743.1 - 0.15 12.3 0.2 0.2 11.8 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM81743.1 - 0.15 12.3 0.2 0.23 11.7 0.2 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM81743.1 - 0.2 12.2 0.0 0.24 11.9 0.0 1.1 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 KFM81743.1 - 0.24 10.7 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Peptidase_C15 PF01470.17 KFM81744.1 - 1.4e-24 87.4 0.0 1.7e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase PgaPase_1 PF06162.12 KFM81744.1 - 6.4e-11 42.3 0.0 9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Putative pyroglutamyl peptidase PgaPase_1 Mod_r PF07200.13 KFM81748.1 - 1.5e-43 148.4 21.0 1.9e-43 148.1 21.0 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Vps51 PF08700.11 KFM81748.1 - 0.03 14.4 5.6 10 6.3 0.1 3.4 3 0 0 3 3 3 0 Vps51/Vps67 DUF2378 PF09536.10 KFM81748.1 - 0.062 13.2 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) UPF0259 PF06790.11 KFM81748.1 - 0.22 11.3 0.7 0.25 11.1 0.1 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0259) HSP70 PF00012.20 KFM81748.1 - 0.35 9.0 8.1 0.44 8.7 8.1 1.1 1 0 0 1 1 1 0 Hsp70 protein Fib_alpha PF08702.10 KFM81748.1 - 1.3 9.2 9.3 1.1 9.5 7.8 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 KFM81748.1 - 2.2 8.8 7.6 12 6.4 6.7 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Cdh1_DBD_1 PF18196.1 KFM81748.1 - 2.7 8.3 11.1 0.36 11.2 5.4 2.2 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 dDENN PF03455.19 KFM81752.1 - 2.7e-10 40.1 6.5 3.2e-10 39.8 4.7 2.0 2 0 0 2 2 2 1 dDENN domain DUF1075 PF06388.11 KFM81753.1 - 0.14 12.2 0.1 0.16 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) DUF4518 PF15008.6 KFM81754.1 - 0.00029 20.1 0.1 0.00029 20.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) DUF4518 PF15008.6 KFM81755.1 - 3.2e-10 39.6 0.0 3.4e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) Ribosomal_L11 PF00298.19 KFM81755.1 - 0.084 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Peptidase_M13_N PF05649.13 KFM81756.1 - 5.6e-08 32.9 0.1 6e-08 32.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M13 Ig_3 PF13927.6 KFM81758.1 - 0.0028 18.2 0.2 0.0041 17.7 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin domain CRAL_TRIO PF00650.20 KFM81761.1 - 1.8e-28 99.2 0.1 4.6e-28 97.9 0.0 1.6 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM81761.1 - 0.0002 21.5 1.7 0.0005 20.2 1.7 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM81761.1 - 0.028 14.6 0.0 0.067 13.3 0.0 1.6 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain AAA_11 PF13086.6 KFM81762.1 - 8.4e-20 71.6 2.9 1.1e-19 71.3 2.9 1.1 1 0 0 1 1 1 1 AAA domain FliD_N PF02465.18 KFM81762.1 - 0.046 14.4 2.3 0.046 14.4 2.3 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FHA PF00498.26 KFM81763.1 - 2.1e-14 53.6 0.1 6.4e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFM81763.1 - 2.9e-05 24.3 0.0 5.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain AAA_11 PF13086.6 KFM81764.1 - 3.2e-55 187.7 0.2 3.2e-55 187.7 0.2 3.3 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 KFM81764.1 - 5.2e-54 182.9 0.1 5.2e-54 182.9 0.1 3.7 5 1 1 6 6 6 1 AAA domain AAA_19 PF13245.6 KFM81764.1 - 2.9e-12 47.2 0.0 9.4e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM81764.1 - 6e-09 35.9 0.0 0.00025 20.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KFM81764.1 - 1.7e-06 27.9 7.8 9.5e-05 22.2 0.1 4.3 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KFM81764.1 - 1.2e-05 25.0 2.9 1.2e-05 25.0 2.9 4.2 2 2 1 3 3 2 2 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KFM81764.1 - 2.5e-05 24.3 1.6 0.00029 20.9 0.1 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KFM81764.1 - 0.00076 19.4 0.0 0.015 15.2 0.0 2.7 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 KFM81764.1 - 0.0016 17.9 0.0 0.28 10.6 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein Enkurin PF13864.6 KFM81764.1 - 0.0083 16.5 4.1 0.0083 16.5 4.1 2.8 2 0 0 2 2 1 1 Calmodulin-binding Zeta_toxin PF06414.12 KFM81764.1 - 0.017 14.4 0.0 0.06 12.6 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 KFM81764.1 - 0.029 14.8 0.0 0.082 13.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KFM81764.1 - 0.031 13.4 0.2 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein UvrD_C_2 PF13538.6 KFM81764.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain NTPase_1 PF03266.15 KFM81764.1 - 0.064 13.2 0.1 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 KFM81764.1 - 0.11 12.8 0.0 0.64 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFM81764.1 - 0.12 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KFM81764.1 - 0.15 12.1 1.1 3 7.9 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFM81764.1 - 0.2 12.1 4.8 2 8.8 0.0 4.3 4 0 0 4 4 4 0 RNA helicase AAA_7 PF12775.7 KFM81764.1 - 0.39 10.2 2.9 0.44 10.0 0.0 2.5 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_12 PF13087.6 KFM81765.1 - 9.8e-40 136.3 0.6 1.9e-39 135.3 0.2 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFM81765.1 - 2.7e-19 70.0 0.0 1.2e-09 38.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KFM81765.1 - 9.8e-10 38.6 0.2 0.001 18.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KFM81765.1 - 3.3e-07 30.8 0.0 7.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFM81765.1 - 0.00025 21.1 0.4 0.00084 19.4 0.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFM81765.1 - 0.00035 20.3 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM81765.1 - 0.0011 19.2 0.1 0.076 13.3 0.0 2.7 2 1 1 3 3 3 1 AAA domain Torsin PF06309.11 KFM81765.1 - 0.0095 16.0 0.2 0.088 12.9 0.0 2.5 3 0 0 3 3 3 1 Torsin AAA_16 PF13191.6 KFM81765.1 - 0.015 15.7 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.6 KFM81765.1 - 0.023 14.5 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 KFM81765.1 - 0.028 13.8 0.4 0.043 13.2 0.4 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KFM81765.1 - 0.041 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KFM81765.1 - 0.12 11.6 0.1 1.4 8.0 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KFM81765.1 - 0.17 12.0 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain FHA PF00498.26 KFM81766.1 - 4.4e-12 46.2 0.0 1.1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM81766.1 - 8.9e-07 29.1 0.0 3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Bacillus_HBL PF05791.11 KFM81767.1 - 0.06 13.2 0.1 0.065 13.1 0.1 1.0 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Eclosion PF04736.12 KFM81769.1 - 3.8e-20 71.3 3.7 5e-20 70.9 3.7 1.2 1 0 0 1 1 1 1 Eclosion hormone Eclosion PF04736.12 KFM81770.1 - 3.3e-26 90.7 5.0 4.2e-26 90.4 5.0 1.2 1 0 0 1 1 1 1 Eclosion hormone TPR_14 PF13428.6 KFM81771.1 - 2.2e-10 40.5 4.6 0.01 16.6 0.1 5.4 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM81771.1 - 2.7e-09 37.4 5.8 0.0012 19.4 0.3 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM81771.1 - 2.1e-08 33.7 13.8 0.00015 21.6 0.6 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM81771.1 - 1.1e-07 32.3 2.3 0.0078 16.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM81771.1 - 2.6e-06 27.0 7.2 0.083 12.8 0.1 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM81771.1 - 8.1e-06 25.6 6.6 0.0028 17.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 KFM81771.1 - 2.9e-05 23.2 6.3 0.00091 18.3 3.2 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.6 KFM81771.1 - 0.0017 18.8 0.4 0.018 15.5 0.1 2.2 1 1 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_9 PF13371.6 KFM81771.1 - 0.0077 16.4 0.7 0.28 11.3 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 KFM81771.1 - 0.0085 15.1 0.4 0.011 14.7 0.4 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF386 PF04074.12 KFM81771.1 - 0.021 14.7 0.2 0.049 13.5 0.2 1.7 1 1 0 1 1 1 0 YhcH/YjgK/YiaL Colicin_Pyocin PF01320.18 KFM81771.1 - 0.027 14.6 0.0 0.078 13.1 0.0 1.8 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein TPR_6 PF13174.6 KFM81771.1 - 0.047 14.3 7.3 17 6.3 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFM81771.1 - 0.077 13.3 0.4 0.19 12.0 0.1 1.9 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM81771.1 - 0.1 13.0 2.6 33 5.2 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_18 PF13512.6 KFM81771.1 - 0.19 11.8 2.0 3 8.0 0.5 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM81771.1 - 0.84 10.0 5.7 6.9 7.0 0.2 3.9 3 1 2 5 5 5 0 Tetratricopeptide repeat RNA_pol_Rpb4 PF03874.16 KFM81772.1 - 2.6e-27 95.6 3.8 3e-27 95.4 3.8 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 LIM PF00412.22 KFM81773.1 - 1.4e-64 214.1 41.9 1e-16 60.9 3.0 4.2 4 0 0 4 4 4 4 LIM domain Paxillin PF03535.13 KFM81773.1 - 0.00056 19.9 16.1 0.00072 19.5 0.7 3.3 1 1 2 3 3 3 2 Paxillin family zf-dskA_traR PF01258.17 KFM81773.1 - 0.11 12.5 14.3 0.57 10.2 0.3 5.1 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger Calpain_inhib PF00748.19 KFM81773.1 - 8.3 6.9 9.7 26 5.3 7.2 2.5 2 1 0 2 2 2 0 Calpain inhibitor MT-A70 PF05063.14 KFM81774.1 - 2.2e-57 193.7 0.0 3.5e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 MT-A70 DUF5364 PF17322.2 KFM81774.1 - 0.22 11.8 4.5 0.41 10.9 4.2 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5364) PDZ_6 PF17820.1 KFM81776.1 - 4.9e-11 42.3 0.0 1.3e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM81776.1 - 5.7e-07 29.8 0.0 2.3e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM81776.1 - 6.4e-05 23.2 0.4 0.00025 21.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 KFM81776.1 - 0.098 12.6 0.0 0.42 10.6 0.0 2.1 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF824 PF05688.11 KFM81776.1 - 4.7 7.1 5.8 59 3.6 0.2 3.7 1 1 2 3 3 3 0 Salmonella repeat of unknown function (DUF824) Pkinase PF00069.25 KFM81777.1 - 2.5e-25 89.4 0.0 3.2e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM81777.1 - 2.4e-08 33.6 0.0 6.2e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFM81777.1 - 0.53 11.0 4.2 1.3 9.8 4.2 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Ricin_B_lectin PF00652.22 KFM81779.1 - 5.9e-14 52.4 0.1 8.9e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFM81779.1 - 5.5e-06 25.9 0.7 1e-05 25.1 0.7 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase NAD_binding_4 PF07993.12 KFM81780.1 - 0.035 13.3 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein NAD_binding_4 PF07993.12 KFM81781.1 - 1.9e-56 191.1 0.0 2.3e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KFM81781.1 - 2.3e-08 33.4 0.1 2.3e-07 30.1 0.1 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFM81781.1 - 3.1e-05 23.5 0.2 0.00038 20.0 0.3 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFM81781.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KFM81781.1 - 0.024 15.1 0.0 0.056 13.9 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KFM81781.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KFM81781.1 - 0.19 11.1 0.2 1 8.7 0.2 2.1 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Herpes_US9 PF06072.11 KFM81782.1 - 0.018 14.9 0.4 0.024 14.5 0.4 1.1 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Glyco_hydro_30 PF02055.16 KFM81783.1 - 1.9e-148 494.1 1.5 2.3e-148 493.9 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KFM81783.1 - 0.00011 22.3 0.0 0.0003 20.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KFM81783.1 - 0.00049 19.4 0.1 0.0014 18.0 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Sulfotransfer_1 PF00685.27 KFM81784.1 - 3.3e-21 76.0 0.2 3.9e-21 75.7 0.2 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFM81784.1 - 1.1e-11 45.6 0.2 1.7e-11 44.9 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFM81784.1 - 0.00014 21.9 0.1 0.0016 18.4 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family LRR_8 PF13855.6 KFM81785.1 - 0.011 15.4 0.2 0.033 14.0 0.0 1.8 2 1 0 2 2 2 0 Leucine rich repeat FeS_assembly_P PF01883.19 KFM81787.1 - 0.0002 21.5 0.0 0.00059 19.9 0.0 1.9 3 0 0 3 3 3 1 Iron-sulfur cluster assembly protein Hexokinase_2 PF03727.16 KFM81788.1 - 2.2e-70 236.8 0.0 3.1e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFM81788.1 - 5.2e-59 199.5 0.0 9.4e-59 198.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Sas6_CC PF18594.1 KFM81788.1 - 0.0064 16.2 1.5 0.0094 15.7 0.1 2.1 2 0 0 2 2 2 1 Sas6/XLF/XRCC4 coiled-coil domain UPF0180 PF03698.13 KFM81788.1 - 0.064 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Sec7 PF01369.20 KFM81789.1 - 1.6e-34 119.1 4.1 2.3e-34 118.7 4.1 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 KFM81789.1 - 1.5e-05 24.8 1.1 3.4e-05 23.6 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM81789.1 - 0.00047 19.9 0.3 0.0011 18.8 0.3 1.7 1 0 0 1 1 1 1 F-box domain Zip PF02535.22 KFM81791.1 - 2.2e-72 244.1 6.4 2.2e-72 244.1 6.4 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter DUF1772 PF08592.11 KFM81791.1 - 0.073 13.4 0.4 0.69 10.2 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) MBOAT PF03062.19 KFM81792.1 - 1.3e-19 70.8 0.6 1.4e-19 70.7 0.6 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF5366 PF17328.2 KFM81793.1 - 0.018 15.2 4.9 0.018 15.2 4.9 1.6 2 1 0 2 2 2 0 Family of unknown function (DUF5366) UCH PF00443.29 KFM81794.1 - 9e-63 212.2 0.9 1e-62 212.0 0.2 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM81794.1 - 1.1e-18 67.9 1.3 9.6e-16 58.3 0.0 2.5 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF4780 PF16012.5 KFM81794.1 - 0.037 13.5 0.3 3.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4780) DUF1189 PF06691.11 KFM81795.1 - 0.14 11.7 1.5 1.1 8.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1189) Glyco_hydro_47 PF01532.20 KFM81796.1 - 4.1e-86 289.7 0.0 5e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DM4_12 PF07841.13 KFM81797.1 - 1.3e-06 28.9 0.9 5e-06 27.1 0.3 2.1 2 0 0 2 2 2 1 DM4/DM12 family CLIP_1 PF18322.1 KFM81797.1 - 0.15 12.1 2.0 0.26 11.4 0.3 2.0 2 0 0 2 2 2 0 Serine protease Clip domain PPAF-2 VWA PF00092.28 KFM81798.1 - 4.1e-34 118.3 0.3 5.7e-34 117.9 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain HYR PF02494.16 KFM81798.1 - 2.7e-26 91.7 5.7 4.1e-13 49.5 0.5 3.4 3 0 0 3 3 3 2 HYR domain VWA_2 PF13519.6 KFM81798.1 - 7.8e-14 52.2 0.0 1.3e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ephrin_rec_like PF07699.13 KFM81798.1 - 2.9e-12 46.1 8.0 1.5e-11 43.9 8.0 2.4 1 0 0 1 1 1 1 Putative ephrin-receptor like Sushi PF00084.20 KFM81798.1 - 7.7e-10 39.2 53.5 7.4e-09 36.1 4.6 6.9 6 1 1 7 7 7 4 Sushi repeat (SCR repeat) DUF1194 PF06707.11 KFM81798.1 - 0.0012 18.1 0.1 0.0021 17.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1194) vWA-TerF-like PF10138.9 KFM81798.1 - 0.014 15.5 0.1 0.02 15.0 0.1 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus VWA_CoxE PF05762.14 KFM81798.1 - 0.029 13.8 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein EGF PF00008.27 KFM81799.1 - 6.2e-39 131.9 142.7 8.2e-08 32.4 10.3 10.7 10 0 0 10 10 10 8 EGF-like domain Ephrin_rec_like PF07699.13 KFM81799.1 - 1e-29 102.0 39.2 1.1e-12 47.5 7.5 7.0 7 1 1 8 8 8 4 Putative ephrin-receptor like Pentaxin PF00354.17 KFM81799.1 - 4.8e-26 91.6 1.5 8.4e-26 90.8 1.5 1.3 1 0 0 1 1 1 1 Pentaxin family hEGF PF12661.7 KFM81799.1 - 1e-18 67.2 117.8 1.8e-07 31.5 4.8 11.1 10 0 0 10 10 10 6 Human growth factor-like EGF VWD PF00094.25 KFM81799.1 - 2.8e-11 43.9 0.4 8.3e-11 42.4 0.4 1.9 1 0 0 1 1 1 1 von Willebrand factor type D domain Laminin_G_3 PF13385.6 KFM81799.1 - 1.2e-09 38.5 1.4 2.8e-09 37.3 1.4 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily FXa_inhibition PF14670.6 KFM81799.1 - 5.1e-08 33.1 6.8 5.1e-08 33.1 6.8 12.6 7 4 5 12 12 12 5 Coagulation Factor Xa inhibitory site VWC PF00093.18 KFM81799.1 - 2e-07 31.2 14.8 2e-07 31.2 14.8 9.2 5 3 3 8 8 8 1 von Willebrand factor type C domain EGF_CA PF07645.15 KFM81799.1 - 0.0016 18.6 11.3 0.0016 18.6 11.3 11.9 10 4 2 12 12 12 5 Calcium-binding EGF domain Glyco_hydro_16 PF00722.21 KFM81799.1 - 0.015 14.8 0.6 0.032 13.7 0.6 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 DnaJ PF00226.31 KFM81800.1 - 1.1e-21 76.7 3.0 1.1e-21 76.7 3.0 2.0 2 0 0 2 2 2 1 DnaJ domain RINGv PF12906.7 KFM81801.1 - 1.8e-12 47.2 12.0 4.8e-12 45.8 12.0 1.8 1 0 0 1 1 1 1 RING-variant domain DUF898 PF05987.13 KFM81801.1 - 0.073 12.1 0.4 0.11 11.6 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Cadherin_3 PF16184.5 KFM81803.1 - 2e-182 594.4 30.0 1.4e-24 86.2 0.4 11.3 11 0 0 11 11 11 11 Cadherin-like Cadherin_4 PF17803.1 KFM81803.1 - 1.7e-12 47.7 0.0 1.4 9.6 0.0 7.6 8 0 0 8 8 8 4 Bacterial cadherin-like domain Big_9 PF17963.1 KFM81803.1 - 1.7e-06 28.7 9.0 11 6.8 0.1 9.9 10 1 0 10 10 10 2 Bacterial Ig domain DUF723 PF05265.13 KFM81803.1 - 0.14 12.2 0.0 0.47 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF723) Lectin_C PF00059.21 KFM81804.1 - 2.8e-15 57.0 0.3 6.1e-15 55.9 0.3 1.6 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 KFM81804.1 - 0.0084 15.8 0.2 0.028 14.0 0.2 1.8 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like EF-hand_1 PF00036.32 KFM81805.1 - 5.1e-24 82.0 4.9 1.9e-07 30.1 0.0 5.1 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFM81805.1 - 1.8e-23 80.4 1.7 3.5e-05 23.4 0.0 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KFM81805.1 - 1.3e-20 71.9 3.4 3.9e-06 26.1 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KFM81805.1 - 1.5e-19 70.2 8.6 3.3e-11 43.5 2.3 3.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KFM81805.1 - 7.9e-18 64.1 5.4 3.6e-09 36.3 0.1 4.6 4 1 1 5 5 5 4 EF-hand domain pair Caleosin PF05042.13 KFM81805.1 - 0.00095 19.1 0.3 0.48 10.3 0.1 2.4 1 1 2 3 3 3 2 Caleosin related protein SPARC_Ca_bdg PF10591.9 KFM81805.1 - 0.0069 16.7 0.0 1.9 8.8 0.0 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFM81805.1 - 0.023 14.5 1.7 1.9 8.4 1.8 3.3 2 1 1 3 3 3 0 EF hand EF-hand_13 PF17958.1 KFM81805.1 - 0.075 12.8 0.0 28 4.6 0.0 3.1 1 1 2 3 3 3 0 EF-hand domain LRR_8 PF13855.6 KFM81808.1 - 1.1e-20 73.1 12.2 2.6e-12 46.3 2.3 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFM81808.1 - 4.2e-09 36.5 17.6 5e-05 23.6 3.6 3.9 1 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM81808.1 - 3.4e-06 26.9 13.0 0.11 13.1 0.4 5.3 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 KFM81808.1 - 0.0044 17.0 18.9 0.57 10.4 2.7 4.9 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 KFM81808.1 - 0.014 14.9 5.1 0.071 12.6 5.3 1.8 1 1 0 1 1 1 0 Leucine-rich repeat Viral_env_E26 PF11050.8 KFM81808.1 - 0.024 14.0 0.9 0.16 11.3 1.0 1.9 1 1 1 2 2 2 0 Virus envelope protein E26 LRRNT PF01462.18 KFM81809.1 - 0.0079 15.8 2.1 0.0079 15.8 2.1 2.9 3 2 0 3 3 3 1 Leucine rich repeat N-terminal domain TIR PF01582.20 KFM81810.1 - 1.5e-19 70.5 0.1 2.7e-19 69.7 0.1 1.4 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFM81810.1 - 4.5e-15 56.3 0.1 6.6e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 KFM81810.1 - 0.00071 19.9 0.0 0.0035 17.6 0.0 1.8 2 0 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) SmpB PF01668.18 KFM81810.1 - 0.098 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 SmpB protein GCP_N_terminal PF17681.1 KFM81811.1 - 1.4e-31 110.2 0.1 2.1e-31 109.7 0.1 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFM81812.1 - 5.9e-66 223.0 8.1 7.5e-66 222.7 8.1 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFM81812.1 - 1.9e-12 47.5 2.3 6.5e-12 45.7 0.1 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal Glyco_hydro_20 PF00728.22 KFM81813.1 - 2.7e-25 89.5 0.9 4.1e-25 88.9 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Promethin PF16015.5 KFM81816.1 - 4.5e-15 55.5 15.0 5.2e-15 55.3 15.0 1.1 1 0 0 1 1 1 1 Promethin Tweety PF04906.13 KFM81816.1 - 0.096 11.3 2.9 0.11 11.2 2.3 1.4 1 1 0 1 1 1 0 Tweety PRELI PF04707.14 KFM81817.1 - 2.3e-48 164.0 0.1 3.7e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 KFM81817.1 - 3.6e-40 137.3 0.0 2.3e-39 134.7 0.0 2.2 3 0 0 3 3 3 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM81817.1 - 0.00032 20.8 0.0 0.00077 19.6 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AMP-binding PF00501.28 KFM81818.1 - 2.2e-49 168.2 0.0 2.9e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ion_trans_2 PF07885.16 KFM81819.1 - 0.041 13.8 0.8 0.093 12.7 0.1 2.0 2 0 0 2 2 2 0 Ion channel EpuA PF11772.8 KFM81819.1 - 0.12 12.1 2.2 0.46 10.2 1.4 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta MRP-63 PF14978.6 KFM81820.1 - 2.5e-16 60.1 0.4 2.9e-16 59.8 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 zf-H2C2_2 PF13465.6 KFM81822.1 - 5.8e-61 200.4 62.1 4.1e-10 39.6 0.6 8.5 9 0 0 9 9 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM81822.1 - 9e-40 133.0 79.5 9.5e-06 25.8 1.0 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81822.1 - 1.8e-26 90.5 72.3 0.0024 18.5 2.8 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 KFM81822.1 - 2.6e-19 68.9 72.1 0.0089 16.4 4.3 8.3 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM81822.1 - 2.6e-14 52.8 66.4 0.0013 18.7 2.5 9.0 8 1 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM81822.1 - 4.3e-12 45.6 46.4 0.015 15.0 0.2 8.2 8 0 0 8 8 8 6 C2H2-type zinc-finger domain GAGA PF09237.11 KFM81822.1 - 1.1e-06 28.3 28.2 0.13 12.1 0.3 6.6 2 1 4 6 6 6 5 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM81822.1 - 2.5e-06 27.4 31.2 0.13 12.3 0.9 8.0 1 1 8 9 9 9 3 Sec23/Sec24 zinc finger TRAF6_Z2 PF18048.1 KFM81822.1 - 3.1e-05 24.0 45.0 0.75 9.9 0.2 7.9 8 0 0 8 8 8 6 TNF receptor-associated factor 6 zinc finger 2 BolA PF01722.18 KFM81822.1 - 5.9e-05 23.3 17.3 0.16 12.3 0.5 4.8 1 1 2 5 5 5 2 BolA-like protein DUF2256 PF10013.9 KFM81822.1 - 0.00013 22.1 32.0 3.4 7.9 0.2 8.2 8 0 0 8 8 8 1 Uncharacterized protein conserved in bacteria (DUF2256) Tox-HNH-HHH PF15637.6 KFM81822.1 - 0.00017 21.7 3.2 0.23 11.6 0.0 3.1 2 2 1 3 3 3 3 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_9 PF16293.5 KFM81822.1 - 0.00044 20.0 38.1 0.49 10.3 0.8 7.9 2 2 6 8 8 8 3 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 KFM81822.1 - 0.00047 20.4 54.0 0.25 11.7 1.9 8.6 8 1 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.9 KFM81822.1 - 0.0027 17.7 10.0 62 3.8 0.0 7.2 8 0 0 8 8 8 0 Zinc-finger domain DUF4825 PF16107.5 KFM81822.1 - 0.0036 17.4 0.0 1.5 9.0 0.0 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4825) zf-C2HC_2 PF13913.6 KFM81822.1 - 0.008 16.0 32.8 0.51 10.3 0.1 8.1 8 0 0 8 8 8 2 zinc-finger of a C2HC-type GATase_2 PF00310.21 KFM81822.1 - 0.077 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Zf_RING PF16744.5 KFM81822.1 - 0.081 13.0 49.4 0.55 10.4 1.1 7.9 1 1 6 7 7 7 0 KIAA1045 RING finger ADK_lid PF05191.14 KFM81822.1 - 0.25 11.4 28.4 0.2 11.7 1.4 5.5 2 2 5 7 7 7 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM81822.1 - 0.38 11.1 64.7 1.3 9.4 0.8 7.9 1 1 6 7 7 6 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM81822.1 - 0.5 11.2 36.8 0.28 12.0 3.8 4.6 1 1 5 6 6 6 0 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM81822.1 - 2.5 8.2 37.4 6.8 6.8 3.6 4.2 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type FYVE PF01363.21 KFM81822.1 - 9.6 6.4 54.3 0.73 10.0 12.9 4.4 2 2 0 3 3 3 0 FYVE zinc finger DUF3480 PF11979.8 KFM81824.1 - 4.1e-73 246.4 0.1 4.1e-73 246.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3480) FYVE PF01363.21 KFM81824.1 - 7e-17 61.3 10.4 7e-17 61.3 10.4 3.0 2 0 0 2 2 2 1 FYVE zinc finger SARA PF11409.8 KFM81824.1 - 1.1e-16 60.7 6.1 3.7e-16 59.0 6.1 2.0 1 0 0 1 1 1 1 Smad anchor for receptor activation (SARA) TMF_DNA_bd PF12329.8 KFM81828.1 - 0.51 10.4 11.4 0.063 13.3 5.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cut12 PF11500.8 KFM81828.1 - 4.2 7.3 6.4 1.3 9.0 2.3 1.9 2 0 0 2 2 2 0 Spindle pole body formation-associated protein WD40 PF00400.32 KFM81829.1 - 3.5e-10 40.3 5.2 0.0014 19.4 0.0 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM81829.1 - 4.2e-05 23.7 0.0 1 9.7 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ank_3 PF13606.6 KFM81830.1 - 6.4e-11 41.5 0.4 3.2e-07 30.1 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFM81830.1 - 7.9e-09 35.6 0.1 1.1e-06 28.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM81830.1 - 3.6e-08 33.9 0.0 5.8e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM81830.1 - 3.8e-08 33.7 0.0 6.3e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM81830.1 - 8.5e-08 32.3 1.2 5e-07 29.9 0.5 2.2 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KFM81831.1 - 8.5e-14 51.7 1.8 6.5e-07 29.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM81831.1 - 5.7e-11 42.8 0.1 1.3e-10 41.7 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM81831.1 - 1.9e-10 40.0 0.6 2.2e-05 24.5 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFM81831.1 - 5.1e-10 39.4 3.4 2.7e-07 30.7 0.2 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFM81831.1 - 6.7e-07 29.5 0.2 0.0031 17.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SdrD_B PF17210.3 KFM81833.1 - 0.024 14.9 0.1 0.041 14.1 0.1 1.3 1 0 0 1 1 1 0 SdrD B-like domain PID PF00640.23 KFM81834.1 - 6.3e-21 74.9 2.5 1.5e-20 73.6 2.5 1.7 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFM81834.1 - 0.00052 20.2 0.5 0.00083 19.5 0.5 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFM81834.1 - 0.00056 19.8 0.4 0.00081 19.3 0.4 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SAM_1 PF00536.30 KFM81834.1 - 0.0029 18.0 0.3 0.02 15.3 0.0 2.5 2 2 0 2 2 2 1 SAM domain (Sterile alpha motif) OB_NTP_bind PF07717.16 KFM81838.1 - 5.4e-27 94.0 0.0 1.3e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFM81838.1 - 4.3e-26 91.3 0.1 7.4e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) S1 PF00575.23 KFM81839.1 - 9.7e-15 54.7 0.3 2e-14 53.7 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.31 KFM81839.1 - 7.8e-14 52.0 0.0 2.9e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM81839.1 - 0.00013 21.8 0.1 0.00038 20.3 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFM81839.1 - 0.00016 22.0 0.0 0.00058 20.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM81839.1 - 0.0011 18.7 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFM81839.1 - 0.0027 16.8 0.2 0.0065 15.6 0.2 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KFM81839.1 - 0.01 16.2 0.1 0.031 14.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFM81839.1 - 0.018 14.3 0.0 0.06 12.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KFM81839.1 - 0.13 12.6 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 KFM81839.1 - 0.13 11.7 0.0 0.34 10.3 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein DUF4551 PF15087.6 KFM81839.1 - 0.15 10.9 12.6 0.89 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Macoilin PF09726.9 KFM81839.1 - 0.18 10.3 9.5 0.36 9.3 9.5 1.5 1 0 0 1 1 1 0 Macoilin family SPATIAL PF15256.6 KFM81839.1 - 0.3 11.4 6.0 0.77 10.1 6.0 1.7 1 0 0 1 1 1 0 SPATIAL Ndc1_Nup PF09531.10 KFM81839.1 - 2.6 6.7 6.6 3.9 6.1 6.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KFM81839.1 - 9.5 4.9 7.2 18 3.9 7.2 1.4 1 0 0 1 1 1 0 Presenilin CLTH PF10607.9 KFM81840.1 - 3.7e-44 150.2 0.0 5.5e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KFM81840.1 - 9.1e-26 90.3 0.1 1.8e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KFM81840.1 - 0.00014 21.6 0.0 0.00035 20.4 0.0 1.7 1 0 0 1 1 1 1 LisH Neuro_bHLH PF12533.8 KFM81840.1 - 0.17 13.1 4.2 0.47 11.7 4.2 1.7 1 0 0 1 1 1 0 Neuronal helix-loop-helix transcription factor SH3_9 PF14604.6 KFM81841.1 - 6.7e-15 54.7 0.7 1.7e-14 53.4 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFM81841.1 - 1.9e-13 49.8 0.0 3.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM81841.1 - 1.2e-10 40.9 0.1 2.3e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain CCDC14 PF15254.6 KFM81841.1 - 0.028 13.1 8.8 0.035 12.8 8.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Vpu PF00558.19 KFM81841.1 - 0.26 11.1 0.3 0.46 10.3 0.3 1.3 1 0 0 1 1 1 0 Vpu protein SH3_9 PF14604.6 KFM81842.1 - 0.00055 19.8 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM81842.1 - 0.0032 17.0 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain DUF3974 PF13120.6 KFM81844.1 - 0.037 14.1 0.1 0.037 14.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) RAI16-like PF10257.9 KFM81845.1 - 3.8e-22 78.6 0.2 5.8e-22 78.1 0.2 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein RAI16-like PF10257.9 KFM81846.1 - 1.3e-48 165.7 1.8 1.7e-48 165.4 1.8 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein UbiA PF01040.18 KFM81848.1 - 1.2e-51 175.5 16.4 1.4e-51 175.2 16.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DALR_1 PF05746.15 KFM81849.1 - 7.2e-15 55.2 0.0 8.1e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 KFM81851.1 - 1.5e-74 251.0 0.3 2.1e-74 250.6 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) Haem_oxygenas_2 PF14518.6 KFM81851.1 - 0.016 15.0 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Iron-containing redox enzyme Rootletin PF15035.6 KFM81851.1 - 0.083 12.9 0.3 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DALR_2 PF09190.11 KFM81851.1 - 0.091 13.2 0.0 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 DALR domain FMO-like PF00743.19 KFM81852.1 - 4.8e-174 579.7 0.0 5.4e-174 579.5 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM81852.1 - 6.4e-18 65.0 0.9 5.9e-14 52.0 0.2 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM81852.1 - 1.1e-11 44.6 0.1 7.3e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM81852.1 - 2.5e-11 43.3 0.1 1.4e-07 31.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFM81852.1 - 0.021 14.4 2.0 5.5 6.5 0.0 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM81852.1 - 0.022 15.0 0.1 0.05 13.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Peptidase_M17_N PF02789.17 KFM81852.1 - 0.028 14.3 0.1 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Pyr_redox PF00070.27 KFM81852.1 - 0.13 12.8 0.2 0.13 12.8 0.2 3.6 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFM81852.1 - 0.2 11.0 0.4 1.7 8.0 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KFM81852.1 - 0.25 10.0 1.0 1.1 7.9 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein RTP1_C1 PF10363.9 KFM81853.1 - 5e-33 113.6 0.1 1.7e-32 112.0 0.1 2.0 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KFM81853.1 - 0.058 13.8 0.0 0.25 11.7 0.0 2.1 1 0 0 1 1 1 0 HEAT repeats RTP1_C2 PF10304.9 KFM81854.1 - 1.8e-05 24.3 0.5 1.8e-05 24.3 0.5 1.8 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT PF02985.22 KFM81854.1 - 6.8e-05 22.8 0.1 0.47 10.8 0.2 2.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 KFM81854.1 - 0.024 15.0 0.0 0.039 14.4 0.0 1.5 1 1 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.6 KFM81854.1 - 0.034 14.7 0.1 0.098 13.2 0.1 1.9 1 1 0 1 1 1 0 HEAT-like repeat Cnd1 PF12717.7 KFM81854.1 - 0.052 13.6 2.3 0.069 13.2 2.3 1.4 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 LRR_8 PF13855.6 KFM81855.1 - 3.1e-19 68.5 17.2 4e-10 39.3 0.9 3.4 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM81855.1 - 5.9e-14 52.0 16.6 5e-05 23.6 0.8 4.5 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM81855.1 - 0.0043 16.6 8.3 0.0067 16.0 0.6 2.3 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KFM81855.1 - 0.0097 15.9 15.7 0.77 10.0 0.0 5.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 KFM81855.1 - 2 9.3 22.1 5.9 7.8 0.2 6.8 6 2 0 6 6 6 0 Leucine Rich Repeat Man-6-P_recep PF02157.15 KFM81857.1 - 1.1e-21 77.1 0.1 1.2e-21 76.9 0.1 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 KFM81857.1 - 0.0033 17.5 0.0 0.005 16.9 0.0 1.3 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat Fcf1 PF04900.12 KFM81858.1 - 9.5e-22 77.3 0.6 1e-21 77.1 0.6 1.0 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KFM81858.1 - 3.3e-05 24.2 0.0 3.5e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 PIN like domain I-set PF07679.16 KFM81859.1 - 1.4e-30 105.1 0.0 2.1e-16 59.8 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM81859.1 - 4.7e-29 100.8 0.1 1.1e-13 51.6 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFM81859.1 - 6.7e-22 77.6 0.0 8.1e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM81859.1 - 1e-17 64.0 0.4 9.7e-09 35.3 0.0 3.6 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFM81859.1 - 1.4e-12 47.7 3.9 0.00039 20.6 0.2 4.8 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM81859.1 - 5.7e-07 29.0 0.1 0.00053 19.5 0.0 3.1 3 1 1 4 4 4 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFM81859.1 - 1.6e-06 28.1 0.0 0.024 14.7 0.0 2.5 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFM81859.1 - 0.00011 22.6 0.0 0.062 13.7 0.0 2.5 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Receptor_2B4 PF11465.8 KFM81859.1 - 0.024 14.8 0.1 2.3 8.4 0.0 2.5 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 Ig_4 PF16680.5 KFM81859.1 - 0.044 14.0 0.0 7.3 6.9 0.0 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Ig_3 PF13927.6 KFM81860.1 - 0.00037 21.0 0.0 0.00039 21.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFM81860.1 - 0.015 15.3 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.25 KFM81860.1 - 0.017 15.3 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 KFM81860.1 - 0.022 15.1 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain wnt PF00110.19 KFM81862.1 - 2.4e-102 342.7 14.3 2.7e-102 342.5 14.3 1.0 1 0 0 1 1 1 1 wnt family EndoU_bacteria PF14436.6 KFM81862.1 - 0.0038 17.6 0.0 0.0072 16.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial EndoU nuclease Ribonuclease_P PF00825.18 KFM81862.1 - 0.027 14.6 0.0 0.068 13.3 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease P CRAL_TRIO PF00650.20 KFM81863.1 - 1.8e-22 79.7 0.3 2.6e-22 79.2 0.3 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM81863.1 - 1.7e-08 34.7 0.1 2.6e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Coatomer_E PF04733.14 KFM81863.1 - 0.09 12.2 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Coatomer epsilon subunit Bcl-2 PF00452.19 KFM81864.1 - 1.8e-10 41.4 0.0 2.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family 2OG-FeII_Oxy_2 PF13532.6 KFM81865.1 - 0.0082 16.3 0.0 0.039 14.1 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CH PF00307.31 KFM81870.1 - 5.1e-22 78.1 0.1 1.3e-21 76.8 0.1 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain Smoothelin PF12510.8 KFM81870.1 - 6.4e-09 35.7 0.4 1.7e-08 34.4 0.4 1.7 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein CAMSAP_CH PF11971.8 KFM81870.1 - 9e-07 28.6 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Peptidase_S46 PF10459.9 KFM81870.1 - 0.31 9.6 6.8 0.41 9.2 6.8 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF349 PF03993.12 KFM81870.1 - 2.6 8.4 18.7 0.36 11.2 0.5 3.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) KH_1 PF00013.29 KFM81871.1 - 3.5e-11 42.7 0.3 1.2e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 KH domain Granulin PF00396.18 KFM81872.1 - 4.4e-16 58.9 89.4 3e-09 37.0 19.9 6.7 3 3 3 6 6 6 4 Granulin Granulin PF00396.18 KFM81873.1 - 9.3e-14 51.5 85.0 1e-07 32.2 22.7 6.5 3 3 4 7 7 7 3 Granulin Hydrolase_4 PF12146.8 KFM81875.1 - 6.8e-16 58.3 0.0 5e-11 42.3 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM81875.1 - 4e-13 49.6 0.0 3.6e-09 36.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM81875.1 - 2.1e-09 38.3 0.0 1.2e-08 35.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFM81875.1 - 0.00039 20.0 0.0 0.00065 19.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KFM81875.1 - 0.0004 20.3 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFM81875.1 - 0.0031 17.4 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KFM81875.1 - 0.0059 16.2 0.0 0.1 12.2 0.0 2.2 1 1 1 2 2 2 1 Lipid-droplet associated hydrolase DLH PF01738.18 KFM81875.1 - 0.0093 15.5 0.0 0.033 13.7 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF900 PF05990.12 KFM81875.1 - 0.027 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S28 PF05577.12 KFM81875.1 - 0.055 12.2 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Thioesterase PF00975.20 KFM81875.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PP28 PF10252.9 KFM81876.1 - 5.4e-27 94.1 19.9 5.4e-27 94.1 19.9 3.0 2 2 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 Gly_transf_sug PF04488.15 KFM81876.1 - 0.033 14.8 0.1 0.051 14.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif Microtub_bind PF13931.6 KFM81876.1 - 0.76 10.1 26.2 0.021 15.2 17.8 2.0 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding CRT10 PF08728.10 KFM81876.1 - 4.2 5.4 15.0 5.2 5.1 15.0 1.1 1 0 0 1 1 1 0 CRT10 Histone PF00125.24 KFM81878.1 - 7.6e-54 181.6 1.6 8.5e-54 181.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFM81878.1 - 7.9e-05 22.7 0.2 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFM81878.1 - 0.00015 22.3 2.4 0.00019 22.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFM81878.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFM81878.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ank_2 PF12796.7 KFM81879.1 - 2.5e-17 63.2 0.1 1.6e-09 38.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM81879.1 - 4.4e-14 51.2 4.1 0.00041 20.6 0.0 5.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KFM81879.1 - 1.4e-12 47.5 0.7 0.00071 19.8 0.0 5.2 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM81879.1 - 4.2e-12 46.3 0.6 0.00014 22.4 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM81879.1 - 2.3e-11 43.6 2.7 0.0007 19.9 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ribo_biogen_C PF04034.13 KFM81881.1 - 2.2e-52 176.1 0.0 3e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KFM81881.1 - 1.9e-14 53.2 0.1 3.1e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI RUN PF02759.19 KFM81882.1 - 1.7e-16 60.4 0.0 2.7e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 RUN domain PID PF00640.23 KFM81882.1 - 3.3e-06 27.2 0.4 5.7e-06 26.4 0.4 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ_2 PF13180.6 KFM81882.1 - 0.00058 20.1 0.0 0.0071 16.7 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFM81882.1 - 0.026 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 KFM81882.1 - 0.04 14.3 0.3 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 PDZ domain PCI PF01399.27 KFM81884.1 - 6.8e-18 65.1 0.1 2e-17 63.6 0.1 1.9 1 0 0 1 1 1 1 PCI domain Mito_morph_reg PF14972.6 KFM81885.1 - 7.1e-50 168.8 0.1 8e-50 168.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial morphogenesis regulator PB1 PF00564.24 KFM81886.1 - 1.1e-10 41.3 0.2 1.7e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 PB1 domain RP-C_C PF11800.8 KFM81886.1 - 2.2 8.3 9.6 0.12 12.5 2.0 2.2 2 1 0 2 2 2 0 Replication protein C C-terminal region TIP41 PF04176.13 KFM81887.1 - 9e-16 57.8 0.2 1.1e-15 57.6 0.2 1.1 1 0 0 1 1 1 1 TIP41-like family Acyl_transf_3 PF01757.22 KFM81889.1 - 0.00033 19.8 2.6 0.00033 19.8 2.6 2.0 3 0 0 3 3 3 1 Acyltransferase family Acyl_transf_3 PF01757.22 KFM81890.1 - 0.0012 17.9 9.3 0.0014 17.7 9.3 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.12 KFM81890.1 - 0.0022 17.6 2.1 0.0029 17.2 2.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1624) SecG PF03840.14 KFM81890.1 - 2.2 8.4 5.5 0.91 9.7 0.7 2.5 2 1 1 3 3 3 0 Preprotein translocase SecG subunit Aminotran_1_2 PF00155.21 KFM81891.1 - 4.1e-68 230.2 0.0 4.6e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFM81891.1 - 1.6e-07 30.6 0.0 3.6e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KFM81891.1 - 1e-06 27.6 0.0 1.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KFM81891.1 - 9.2e-05 21.9 0.0 0.00021 20.7 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFM81891.1 - 0.0019 17.6 0.4 0.006 15.9 0.4 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3481 PF11980.8 KFM81891.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Luteo_P1-P2 PF08467.10 KFM81891.1 - 0.22 10.8 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Rad10 PF03834.14 KFM81892.1 - 5e-47 158.6 0.0 1.4e-46 157.2 0.0 1.7 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KFM81892.1 - 7.4e-10 39.3 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KFM81892.1 - 3.7e-06 26.9 0.0 6.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 KFM81892.1 - 0.00031 20.5 0.0 0.00066 19.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Dus PF01207.17 KFM81893.1 - 5.2e-75 252.4 0.3 8.5e-75 251.7 0.0 1.4 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 KFM81893.1 - 0.0024 17.7 0.2 0.18 11.5 0.0 2.2 1 1 1 2 2 2 2 SOR/SNZ family His_biosynth PF00977.21 KFM81893.1 - 0.0044 16.5 0.1 0.017 14.6 0.0 1.9 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KFM81893.1 - 0.0097 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Ribosomal_S14 PF00253.21 KFM81893.1 - 0.24 11.2 3.9 0.076 12.8 0.7 1.9 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Metallothio PF00131.20 KFM81894.1 - 0.62 10.2 31.8 2 8.6 19.9 2.1 1 1 1 2 2 2 0 Metallothionein TCR PF03638.15 KFM81894.1 - 3.9 7.9 29.5 26 5.2 16.7 2.7 1 1 1 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain CRAL_TRIO PF00650.20 KFM81896.1 - 9.5e-25 87.2 0.0 1.1e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM81896.1 - 0.075 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain SHIPPO-rpt PF07004.12 KFM81897.1 - 1.7e-34 117.1 10.2 6.9e-05 23.6 0.0 6.3 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat DUF2738 PF10927.8 KFM81897.1 - 0.00093 18.4 0.3 3.1 6.8 0.0 3.8 3 1 0 4 4 4 3 Protein of unknown function (DUF2738) DNA_methylase PF00145.17 KFM81898.1 - 3e-13 49.8 0.0 3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KFM81899.1 - 8e-33 112.9 2.0 3.2e-16 59.3 0.1 3.0 3 0 0 3 3 3 2 BAH domain DNA_methylase PF00145.17 KFM81899.1 - 4e-30 105.3 0.2 1e-29 104.0 0.1 1.8 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase zf-CXXC PF02008.20 KFM81899.1 - 5.1e-15 55.2 19.0 5.1e-15 55.2 19.0 2.2 2 0 0 2 2 2 1 CXXC zinc finger domain DNMT1-RFD PF12047.8 KFM81899.1 - 0.0048 16.9 0.2 0.012 15.7 0.2 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain DUF1904 PF08921.11 KFM81899.1 - 0.056 13.7 0.0 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) PBP1_TM PF14812.6 KFM81899.1 - 1 9.8 3.2 14 6.1 0.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNMT1-RFD PF12047.8 KFM81900.1 - 1.6e-14 54.2 0.0 1.9e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Ras PF00071.22 KFM81902.1 - 1.4e-32 112.5 0.1 1.9e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM81902.1 - 2.3e-27 95.6 0.3 3.3e-27 95.1 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM81902.1 - 2.4e-08 33.6 1.0 3.3e-08 33.2 1.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM81902.1 - 0.0055 16.8 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM81902.1 - 0.014 14.8 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM81902.1 - 0.042 13.3 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFM81902.1 - 0.15 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Trypsin PF00089.26 KFM81903.1 - 4.1e-30 105.3 0.0 5.2e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM81903.1 - 3.4e-06 27.4 0.0 5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFM81903.1 - 0.0011 19.9 0.0 0.002 19.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF5479 PF17575.2 KFM81904.1 - 0.13 12.8 0.2 0.16 12.6 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5479) B-block_TFIIIC PF04182.12 KFM81905.1 - 0.05 13.8 0.1 0.05 13.8 0.1 1.1 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC COG5 PF10392.9 KFM81908.1 - 6.4e-29 100.8 3.5 1.2e-28 99.9 3.5 1.5 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KFM81908.1 - 3e-07 30.4 0.4 1.2e-06 28.5 0.3 2.1 1 1 1 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 KFM81908.1 - 0.00034 20.7 1.8 0.0006 19.9 1.8 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 KFM81908.1 - 0.00049 19.5 2.4 0.00065 19.1 2.4 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex HAUS-augmin3 PF14932.6 KFM81908.1 - 0.097 12.2 2.1 0.17 11.5 1.5 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 MTCP1 PF08991.10 KFM81909.1 - 1.4e-11 44.4 13.8 1.1e-10 41.6 13.8 1.8 1 1 1 2 2 2 1 Mature-T-Cell Proliferation I type BTAD PF03704.17 KFM81909.1 - 0.024 15.1 0.1 0.028 14.9 0.1 1.1 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Sybindin PF04099.12 KFM81910.1 - 7.1e-40 136.2 0.7 7.9e-40 136.1 0.7 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KFM81910.1 - 1.4e-07 31.7 0.6 1.9e-07 31.3 0.6 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Cullin_Nedd8 PF10557.9 KFM81911.1 - 2.5e-21 75.5 0.1 2.8e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 KFM81911.1 - 0.063 13.6 0.1 0.063 13.6 0.1 1.0 1 0 0 1 1 1 0 Penicillinase repressor Cullin PF00888.22 KFM81912.1 - 1.9e-220 733.7 17.4 2.1e-220 733.5 17.4 1.0 1 0 0 1 1 1 1 Cullin family TnpV PF14198.6 KFM81912.1 - 1.1 9.3 7.5 0.77 9.8 2.0 2.8 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Glyco_hydro_4C PF11975.8 KFM81912.1 - 2 8.4 5.5 5.9 6.9 2.4 2.7 2 1 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain Adaptin_N PF01602.20 KFM81913.1 - 1.2e-06 27.4 2.8 0.00015 20.5 0.1 2.7 2 0 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 KFM81913.1 - 8.2e-05 22.5 4.1 1.7 9.1 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KFM81913.1 - 0.0011 19.0 5.0 0.0032 17.5 0.3 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM81913.1 - 0.0018 18.6 0.1 1.1 9.7 0.2 3.7 2 1 1 3 3 3 1 HEAT repeats HSR PF03172.13 KFM81913.1 - 0.024 14.8 3.1 5.6 7.2 0.3 3.3 3 0 0 3 3 3 0 HSR domain DUF4042 PF13251.6 KFM81913.1 - 0.053 13.2 1.6 19 4.9 0.0 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 KFM81913.1 - 1.4 9.5 4.8 40 4.8 0.1 3.9 4 0 0 4 4 4 0 HEAT-like repeat PRANC PF09372.10 KFM81913.1 - 2.7 8.4 6.8 2.3 8.6 0.4 3.8 4 0 0 4 4 4 0 PRANC domain Rav1p_C PF12234.8 KFM81914.1 - 0.026 13.0 0.8 0.036 12.5 0.8 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal RNA_helicase PF00910.22 KFM81914.1 - 0.028 14.8 0.2 0.57 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase TMPIT PF07851.13 KFM81915.1 - 8.4 5.5 7.4 9.9 5.3 7.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DDE_Tnp_1_7 PF13843.6 KFM81917.1 - 1.5e-14 54.1 0.1 1.7e-14 53.9 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF4070 PF13282.6 KFM81917.1 - 0.059 13.5 0.1 0.075 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) Sec8_exocyst PF04048.14 KFM81918.1 - 2.8e-14 53.2 5.5 2.8e-14 53.2 5.5 3.8 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KFM81918.1 - 2.8e-08 33.4 10.4 2.8e-08 33.4 10.4 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Cob_adeno_trans PF01923.18 KFM81918.1 - 0.087 13.0 0.8 2.3 8.3 0.3 3.0 2 0 0 2 2 2 0 Cobalamin adenosyltransferase RIH_assoc PF08454.11 KFM81918.1 - 1.8 8.4 6.2 11 5.9 0.8 3.8 3 1 0 3 3 3 0 RyR and IP3R Homology associated Arf PF00025.21 KFM81919.1 - 4.2e-79 264.0 0.1 5e-79 263.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFM81919.1 - 1e-14 54.4 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFM81919.1 - 4.9e-14 52.6 0.0 6.9e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM81919.1 - 1.4e-12 47.5 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFM81919.1 - 2.1e-11 43.6 1.6 1.4e-07 31.0 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFM81919.1 - 3.7e-10 39.5 0.0 4.5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM81919.1 - 2.9e-05 24.1 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFM81919.1 - 0.0063 15.8 0.4 0.024 14.0 0.1 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase RRM_1 PF00076.22 KFM81920.1 - 4e-31 106.6 0.0 8.9e-16 57.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM81920.1 - 5.2e-05 22.8 0.0 0.0012 18.4 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Es2 PF09751.9 KFM81920.1 - 0.025 14.3 0.2 0.042 13.6 0.2 1.4 1 0 0 1 1 1 0 Nuclear protein Es2 7tm_1 PF00001.21 KFM81921.1 - 9.7e-45 152.9 12.2 1.1e-44 152.8 12.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM81921.1 - 1.3e-11 44.4 10.1 1.4e-11 44.2 10.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFM81921.1 - 1.1e-08 35.1 13.7 1.3e-08 34.8 13.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFM81921.1 - 8.3e-06 25.7 4.3 1.1e-05 25.4 4.3 1.3 1 1 0 1 1 1 1 Olfactory receptor Serpentine_r_xa PF03383.15 KFM81921.1 - 0.086 12.8 4.7 0.047 13.7 2.5 1.6 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Cornichon PF03311.14 KFM81922.1 - 3.6e-51 172.6 8.6 4.4e-51 172.3 8.6 1.0 1 0 0 1 1 1 1 Cornichon protein SfLAP PF11139.8 KFM81922.1 - 0.41 10.0 0.1 0.41 10.0 0.1 2.1 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein F-box PF00646.33 KFM81923.1 - 0.00014 21.6 0.9 0.00014 21.6 0.9 3.1 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KFM81923.1 - 0.00015 21.6 0.6 0.00015 21.6 0.6 2.1 2 0 0 2 2 2 1 F-box-like LIM PF00412.22 KFM81925.1 - 0.047 13.9 0.0 0.055 13.7 0.0 1.1 1 0 0 1 1 1 0 LIM domain tRNA-synt_1c PF00749.21 KFM81927.1 - 4.2e-115 384.0 0.3 4.2e-115 384.0 0.3 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain WHEP-TRS PF00458.20 KFM81927.1 - 1.9e-52 175.2 28.0 8.2e-19 67.5 1.2 4.5 4 0 0 4 4 4 3 WHEP-TRS domain tRNA-synt_1c_C PF03950.18 KFM81927.1 - 8.3e-36 123.5 0.0 8.3e-36 123.5 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain ProRS-C_1 PF09180.11 KFM81927.1 - 4.7e-20 71.6 0.3 1.4e-19 70.0 0.3 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KFM81927.1 - 3.7e-19 68.7 0.0 1.2e-17 63.8 0.0 3.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFM81927.1 - 8.1e-18 65.0 0.0 2.2e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) GST_C_3 PF14497.6 KFM81927.1 - 5.9e-06 26.4 0.2 3.4e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM81927.1 - 2.2e-05 24.6 0.0 0.0001 22.4 0.0 2.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM81927.1 - 0.00076 19.5 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFM81927.1 - 0.036 13.9 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Homeodomain PF00046.29 KFM81928.1 - 7.7e-06 25.7 0.0 1.8e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFM81928.1 - 0.00065 19.5 0.7 0.013 15.4 0.1 2.6 2 0 0 2 2 2 1 Homeobox KN domain CUT PF02376.15 KFM81929.1 - 1.4e-55 185.4 0.1 1.3e-26 92.6 0.0 2.3 2 0 0 2 2 2 2 CUT domain HNF-1_N PF04814.13 KFM81929.1 - 3.9e-06 27.6 1.3 0.045 14.4 0.1 3.2 3 0 0 3 3 3 2 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF3391 PF11871.8 KFM81929.1 - 1.3 9.5 4.1 31 5.1 0.1 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF3391) Molybdopterin PF00384.22 KFM81932.1 - 1.1e-70 238.7 0.0 3.3e-69 233.9 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KFM81932.1 - 2.8e-17 62.5 0.0 6.4e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KFM81932.1 - 1.1e-15 56.8 0.1 3e-15 55.5 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KFM81932.1 - 1.4e-11 44.9 0.1 3.2e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KFM81932.1 - 1.5e-08 34.5 1.7 1.8e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KFM81932.1 - 0.17 11.6 0.1 26 4.5 0.0 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CAP_GLY PF01302.25 KFM81933.1 - 1.5e-47 159.5 2.0 9e-23 80.1 0.2 2.3 2 0 0 2 2 2 2 CAP-Gly domain LRR_8 PF13855.6 KFM81934.1 - 6.9e-63 208.3 50.8 1.6e-14 53.4 3.6 10.1 5 2 6 11 11 11 9 Leucine rich repeat LRR_5 PF13306.6 KFM81934.1 - 2e-28 98.9 17.1 1.4e-11 44.4 0.5 4.1 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM81934.1 - 2.5e-28 97.6 51.1 3.2e-05 24.2 0.5 10.3 6 4 1 10 10 10 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM81934.1 - 3.5e-12 46.2 21.3 0.00051 19.6 2.9 5.7 1 1 5 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 KFM81934.1 - 3e-10 39.2 34.5 1.5 9.7 0.3 12.9 13 1 0 13 13 13 4 Leucine Rich Repeat LRRNT PF01462.18 KFM81934.1 - 6.1 6.6 5.9 1.2 8.9 0.9 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain AC_N PF16214.5 KFM81935.1 - 0.0067 15.6 0.6 0.0068 15.6 0.6 1.0 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DuoxA PF10204.9 KFM81937.1 - 5.4e-28 97.8 1.8 6.9e-28 97.4 1.8 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor ELFV_dehydrog PF00208.21 KFM81938.1 - 1.9e-10 40.9 1.4 1.5e-09 37.9 1.4 2.0 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFM81938.1 - 0.0025 17.7 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ThiF PF00899.21 KFM81938.1 - 0.034 13.5 0.7 0.066 12.6 0.7 1.4 1 0 0 1 1 1 0 ThiF family ATP-synt_J PF04911.12 KFM81938.1 - 0.048 13.2 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP synthase j chain FUSC-like PF12805.7 KFM81938.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS 2-Hacid_dh_C PF02826.19 KFM81938.1 - 0.21 10.9 0.2 0.4 10.0 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arf PF00025.21 KFM81939.1 - 9.9e-71 236.8 0.2 1.1e-70 236.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFM81939.1 - 1.3e-12 47.5 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFM81939.1 - 1e-11 44.7 1.9 5.6e-06 25.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFM81939.1 - 1.6e-11 44.4 0.0 2.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM81939.1 - 1.6e-09 37.5 0.0 2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFM81939.1 - 1.3e-08 34.5 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM81939.1 - 1.1e-05 25.5 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 KFM81939.1 - 0.011 15.1 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Snf7 PF03357.21 KFM81940.1 - 4.4e-39 133.8 19.5 5.4e-39 133.5 19.5 1.1 1 0 0 1 1 1 1 Snf7 Prominin PF05478.11 KFM81940.1 - 0.013 13.5 9.0 0.017 13.1 9.0 1.0 1 0 0 1 1 1 0 Prominin Fe_dep_repr_C PF02742.15 KFM81940.1 - 0.063 13.4 1.1 0.2 11.8 0.2 2.3 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Exonuc_VII_L PF02601.15 KFM81940.1 - 0.97 8.9 8.2 1.2 8.7 8.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MitMem_reg PF13012.6 KFM81940.1 - 9.8 6.6 10.6 6.9 7.1 2.3 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function adh_short PF00106.25 KFM81941.1 - 7.9e-40 136.4 0.0 1.3e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM81941.1 - 5.8e-26 91.5 0.0 1e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM81941.1 - 7.2e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Mad3_BUB1_I_2 PF17014.5 KFM81941.1 - 0.032 14.4 0.1 5 7.3 0.0 2.5 1 1 1 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Epimerase PF01370.21 KFM81941.1 - 0.14 11.6 0.1 0.67 9.4 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NUMOD4 PF07463.11 KFM81941.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 NUMOD4 motif adh_short PF00106.25 KFM81942.1 - 0.0028 17.1 0.0 0.0035 16.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.25 KFM81943.1 - 1.3e-27 96.5 0.1 2.3e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM81943.1 - 1.3e-19 70.7 0.0 1.7e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM81944.1 - 1.3e-05 24.8 0.0 3.2e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase zf-met PF12874.7 KFM81945.1 - 1.1e-08 35.2 5.7 0.0016 18.7 0.4 2.9 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFM81945.1 - 1.3e-07 31.7 11.9 1.9e-06 28.0 0.9 3.1 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM81945.1 - 2.1e-06 28.1 11.4 0.00025 21.6 0.5 2.5 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM81945.1 - 2.7e-06 27.5 9.8 7.7e-05 22.9 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM81945.1 - 1.4e-05 25.2 1.6 0.0067 16.7 0.0 2.8 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM81945.1 - 0.0019 18.5 1.6 0.24 11.7 0.2 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 KFM81945.1 - 0.0035 17.2 0.9 0.0069 16.3 0.9 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF2180 PF09947.9 KFM81945.1 - 0.0036 17.2 0.2 0.0059 16.6 0.2 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2180) zf-Di19 PF05605.12 KFM81945.1 - 0.0059 16.9 2.0 0.0076 16.5 1.2 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFM81945.1 - 0.018 15.0 0.2 0.018 15.0 0.2 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 KFM81945.1 - 0.032 14.7 6.9 0.21 12.1 2.1 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-UBP PF02148.19 KFM81945.1 - 0.033 14.5 1.7 0.059 13.7 1.7 1.6 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-MYST PF17772.1 KFM81945.1 - 0.062 12.9 1.6 5.2 6.7 0.0 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain zf-AN1 PF01428.16 KFM81945.1 - 0.15 12.3 6.5 0.19 11.9 1.2 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger Baculo_gp64 PF03273.13 KFM81945.1 - 0.16 10.7 0.5 0.15 10.8 0.5 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Cas_TM1802 PF09484.10 KFM81945.1 - 0.19 10.4 1.0 0.19 10.5 1.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) zf-CHY PF05495.12 KFM81945.1 - 0.23 12.0 4.9 0.5 10.9 2.1 2.1 1 1 1 2 2 2 0 CHY zinc finger zf_C2H2_ZHX PF18387.1 KFM81945.1 - 2.1 8.1 6.5 0.29 10.8 1.5 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 KFM81945.1 - 4.4 7.3 7.8 2.6 8.0 0.4 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 KFM81946.1 - 4.2e-19 68.0 31.1 1.3e-06 28.6 0.7 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM81946.1 - 2e-13 50.0 37.9 1.3e-06 28.5 0.3 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81946.1 - 5.4e-09 36.1 35.5 0.00044 20.8 0.3 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM81946.1 - 1.5e-07 31.0 7.9 8e-06 25.5 2.6 4.1 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFM81946.1 - 0.00032 21.0 19.6 0.019 15.3 0.4 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM81946.1 - 0.0034 17.6 21.3 0.019 15.2 0.1 4.6 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM81946.1 - 0.0085 15.8 0.9 0.0085 15.8 0.9 4.7 4 1 0 4 4 4 1 zinc-finger C2H2-type FYDLN_acid PF09538.10 KFM81946.1 - 0.012 16.3 1.2 0.35 11.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) BolA PF01722.18 KFM81946.1 - 0.016 15.5 1.0 1.5 9.2 0.0 2.7 2 1 1 3 3 2 0 BolA-like protein zf-C2HE PF16278.5 KFM81946.1 - 0.028 14.9 18.3 0.54 10.8 4.5 3.3 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 KFM81946.1 - 0.029 15.1 14.3 0.65 10.7 1.0 4.1 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats GATA PF00320.27 KFM81946.1 - 0.17 11.5 5.9 5 6.8 0.3 3.3 2 1 0 2 2 2 0 GATA zinc finger zf-LYAR PF08790.11 KFM81946.1 - 0.35 10.8 0.1 0.35 10.8 0.1 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 KFM81946.1 - 0.79 10.1 17.4 1.1 9.7 0.2 3.8 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM81946.1 - 1 9.2 8.6 17 5.4 0.1 3.8 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 KFM81946.1 - 2.4 7.8 11.1 8.6 6.1 0.7 3.3 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn_ribbon_SprT PF17283.2 KFM81946.1 - 3.1 7.8 19.4 1.3 9.0 4.2 3.8 3 1 0 3 3 3 0 SprT-like zinc ribbon domain PP28 PF10252.9 KFM81948.1 - 0.0026 18.2 0.2 0.0034 17.8 0.2 1.2 1 0 0 1 1 1 1 Casein kinase substrate phosphoprotein PP28 DUF4371 PF14291.6 KFM81949.1 - 5.6e-10 39.3 0.1 5.9e-10 39.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) AAA_lid_9 PF17871.1 KFM81949.1 - 0.026 14.4 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA lid domain TRAF_BIRC3_bd PF16673.5 KFM81949.1 - 0.062 13.1 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Popeye PF04831.13 KFM81950.1 - 2.7e-48 163.7 2.7 3.1e-48 163.5 2.7 1.0 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 KFM81950.1 - 0.002 18.1 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Kazal_2 PF07648.15 KFM81951.1 - 2.4e-08 34.0 2.5 2.4e-08 34.0 2.5 2.2 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM81951.1 - 1e-05 25.4 6.5 2.3e-05 24.3 6.5 1.7 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain zf-NOSIP PF15906.5 KFM81951.1 - 0.06 13.5 1.1 0.077 13.1 1.0 1.4 1 1 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Chitin_bind_4 PF00379.23 KFM81954.1 - 2.5e-08 34.3 9.1 2.5e-08 34.3 9.1 2.0 2 0 0 2 2 2 1 Insect cuticle protein DUF1940 PF09155.10 KFM81955.1 - 0.031 14.4 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Med12-LCEWAV PF12145.8 KFM81956.1 - 4.4e-88 296.2 0.1 8.8e-88 295.2 0.1 1.5 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain UDG PF03167.19 KFM81957.1 - 1.5e-08 34.7 0.0 1.6e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pkinase_Tyr PF07714.17 KFM81959.1 - 6.5e-99 330.4 0.0 8.6e-99 330.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 KFM81959.1 - 2.5e-45 152.4 0.0 3e-16 59.3 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Pkinase PF00069.25 KFM81959.1 - 1.2e-42 146.1 0.0 2.1e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 KFM81959.1 - 7.8e-38 129.0 0.1 1e-12 48.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM81959.1 - 4.7e-27 94.1 1.0 5.1e-09 36.4 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFM81959.1 - 1.2e-25 89.5 0.2 1.5e-08 34.7 0.0 4.2 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM81959.1 - 1.8e-20 73.2 6.3 9.1e-06 25.8 0.3 5.7 3 3 1 4 4 4 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFM81959.1 - 1.6e-06 28.4 0.1 0.0063 16.9 0.0 3.5 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM81959.1 - 4.7e-05 23.6 0.2 0.13 12.5 0.0 3.6 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFM81959.1 - 9.5e-05 22.4 0.5 1.6 8.8 0.0 3.5 2 1 1 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFM81959.1 - 0.00055 19.9 0.0 0.5 10.4 0.0 3.8 4 0 0 4 4 4 1 C17orf99 Ig domain Adeno_E3_CR1 PF02440.15 KFM81959.1 - 0.0051 16.6 0.4 1.4 8.8 0.0 3.5 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 KFM81959.1 - 0.017 14.6 5.5 1.8 8.2 0.0 3.9 4 0 0 4 4 4 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFM81959.1 - 0.056 13.5 0.1 41 4.3 0.0 3.2 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Trypsin PF00089.26 KFM81961.1 - 1e-72 244.5 0.0 1.2e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFM81961.1 - 3.6e-07 31.2 0.0 4.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFM81961.1 - 2.7e-05 24.5 0.0 6.7e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 KFM81961.1 - 0.016 14.8 0.0 0.11 12.0 0.0 2.3 2 1 0 2 2 2 0 Chymotrypsin family Peptidase-S1 tRNA-synt_2b PF00587.25 KFM81962.1 - 2.2e-09 37.5 0.1 5.1e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFM81962.1 - 0.00016 21.9 3.4 0.00016 21.9 3.4 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Ribosomal_L34e PF01199.18 KFM81963.1 - 9.4e-42 141.2 3.8 1.1e-41 141.1 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L34e Toxin_28 PF08115.11 KFM81963.1 - 0.34 10.8 5.7 2.7 7.9 0.1 2.6 3 0 0 3 3 3 0 SFI toxin family CTNNB1_binding PF08347.11 KFM81964.1 - 1.4e-08 35.2 1.6 1.7e-08 34.9 1.6 1.2 1 0 0 1 1 1 1 N-terminal CTNNB1 binding HMG_box PF00505.19 KFM81965.1 - 3e-22 78.8 1.5 5.5e-22 78.0 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM81965.1 - 9.4e-09 35.8 3.1 9.4e-09 35.8 3.1 2.0 2 0 0 2 2 2 1 HMG-box domain DUF1133 PF06576.11 KFM81965.1 - 0.075 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) GST_C_3 PF14497.6 KFM81966.1 - 2e-12 47.2 0.0 3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFM81966.1 - 4.3e-08 33.4 0.0 9.7e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFM81966.1 - 2.8e-05 24.4 0.0 5.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFM81966.1 - 0.00053 20.2 0.0 0.0027 18.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFM81966.1 - 0.0035 17.5 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KFM81966.1 - 0.022 15.0 0.0 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin GST_N_4 PF17172.4 KFM81966.1 - 0.035 14.9 0.0 0.15 12.9 0.0 1.8 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain Peptidase_M3_N PF08439.10 KFM81966.1 - 0.17 12.2 0.4 1.6 9.0 0.2 2.3 1 1 1 2 2 2 0 Oligopeptidase F Sec5 PF15469.6 KFM81967.1 - 3.1e-46 157.6 3.8 3.1e-46 157.6 3.8 2.9 2 0 0 2 2 2 1 Exocyst complex component Sec5 TIG PF01833.24 KFM81967.1 - 2.9e-09 36.9 0.1 6.3e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 IPT/TIG domain TPR_20 PF14561.6 KFM81967.1 - 0.043 14.2 0.8 0.16 12.3 0.8 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Phage_int_SAM_4 PF13495.6 KFM81967.1 - 0.085 13.3 2.3 1.1 9.8 0.1 2.9 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain TcpS PF17456.2 KFM81967.1 - 0.11 12.5 0.8 0.63 10.1 0.1 2.4 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S BEN PF10523.9 KFM81968.1 - 5.1e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 BEN domain CTD_bind PF04818.13 KFM81969.1 - 4.7e-07 30.5 0.0 1.5e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3246 PF11596.8 KFM81972.1 - 0.0066 15.9 1.0 0.0092 15.4 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Dynamin_N PF00350.23 KFM81973.1 - 7.4e-07 29.4 0.0 7.4e-07 29.4 0.0 6.9 2 2 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFM81973.1 - 9.7e-07 28.9 0.1 5.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF5600 PF18150.1 KFM81973.1 - 0.00096 19.7 0.1 0.0035 17.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) EHD_N PF16880.5 KFM81973.1 - 0.0091 15.9 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Otopetrin PF03189.13 KFM81974.1 - 1.1e-107 360.6 16.7 1.6e-107 360.1 16.7 1.2 1 0 0 1 1 1 1 Otopetrin DUF2208 PF09973.9 KFM81974.1 - 0.076 12.6 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF3464 PF11947.8 KFM81974.1 - 2.4 7.9 4.9 2.1 8.1 2.4 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Tetraspanin PF00335.20 KFM81974.1 - 6.5 6.4 16.5 2.5 7.8 10.3 2.7 2 0 0 2 2 2 0 Tetraspanin family Otopetrin PF03189.13 KFM81975.1 - 3.7e-47 161.1 8.5 4.1e-47 161.0 8.5 1.0 1 0 0 1 1 1 1 Otopetrin UPF0182 PF03699.13 KFM81975.1 - 0.028 12.6 2.2 0.03 12.5 2.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF5385 PF17359.2 KFM81975.1 - 3.8 7.0 5.4 1.3 8.5 1.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF3810 PF12725.7 KFM81975.1 - 4.2 6.6 7.2 10 5.3 7.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) ABC2_membrane_3 PF12698.7 KFM81975.1 - 5.2 6.1 14.9 28 3.7 14.9 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein S1FA PF04689.13 KFM81975.1 - 5.3 7.3 9.5 1.3 9.2 0.6 2.8 2 1 1 3 3 3 0 DNA binding protein S1FA Otopetrin PF03189.13 KFM81976.1 - 8.6e-43 146.8 2.4 5.1e-42 144.2 0.8 1.9 1 1 1 2 2 2 2 Otopetrin PRD_Mga PF08270.11 KFM81976.1 - 0.048 13.3 0.1 0.064 12.9 0.1 1.1 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain Cu-oxidase_3 PF07732.15 KFM81978.1 - 6.3e-23 81.0 1.2 3.3e-06 27.1 0.0 4.6 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFM81978.1 - 5.5e-19 68.3 18.6 1.6e-08 34.4 2.3 7.2 6 2 0 6 6 6 6 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFM81979.1 - 9.1e-31 106.4 15.0 1.5e-14 53.9 0.7 7.0 6 2 0 6 6 6 5 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFM81979.1 - 2.6e-18 66.1 0.5 6.7e-05 22.9 0.1 4.8 4 1 0 4 4 4 3 Multicopper oxidase DUF1717 PF05414.11 KFM81979.1 - 0.021 15.3 0.1 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Viral domain of unknown function (DUF1717) JHBP PF06585.11 KFM81981.1 - 5.3e-13 48.7 0.1 8.8e-13 48.0 0.1 1.4 1 1 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) SH3_9 PF14604.6 KFM81982.1 - 5.6e-25 86.9 2.4 2.9e-13 49.4 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KFM81982.1 - 9.6e-24 82.7 1.5 8.1e-13 47.8 0.2 2.9 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KFM81982.1 - 6.3e-22 77.0 0.4 3.1e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KFM81982.1 - 2.7e-18 66.0 0.5 8e-18 64.5 0.5 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain NBD94 PF16830.5 KFM81982.1 - 0.012 16.0 1.1 0.012 16.0 1.1 2.3 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH SH3_3 PF08239.11 KFM81982.1 - 0.027 14.7 0.1 0.072 13.4 0.1 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain DUF2203 PF09969.9 KFM81982.1 - 0.11 13.2 10.1 2.4 8.9 1.0 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FAD-oxidase_C PF02913.19 KFM81984.1 - 3.6e-43 148.0 0.0 4.1e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain AMP-binding PF00501.28 KFM81985.1 - 7.2e-59 199.5 0.0 8.5e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM81985.1 - 1.1e-08 34.8 0.7 2.6e-08 33.6 0.7 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus SIR2_2 PF13289.6 KFM81985.1 - 0.14 12.3 0.0 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 SIR2-like domain AMP-binding PF00501.28 KFM81986.1 - 1.9e-14 53.1 0.0 2.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM81986.1 - 4.8e-11 42.4 2.0 4.8e-11 42.4 2.0 1.7 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Rho_RNA_bind PF07497.12 KFM81986.1 - 0.058 13.3 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain TfuA PF07812.12 KFM81986.1 - 0.064 13.0 0.4 0.81 9.4 0.1 2.3 1 1 0 2 2 2 0 TfuA-like protein AMP-binding PF00501.28 KFM81987.1 - 1e-22 80.4 0.0 1.2e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM81987.1 - 0.003 18.5 0.0 0.0054 17.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-H2C2_2 PF13465.6 KFM81988.1 - 2.8e-76 248.8 87.7 1.5e-08 34.7 0.7 12.0 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM81988.1 - 5.6e-54 177.7 94.6 3.3e-06 27.3 1.1 11.4 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM81988.1 - 6e-41 135.6 88.4 0.00023 21.7 1.2 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM81988.1 - 1.8e-32 110.8 82.2 9.3e-05 22.7 1.3 11.3 11 0 0 11 11 11 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM81988.1 - 1.1e-28 98.9 62.8 0.0037 17.5 0.4 11.3 10 1 1 11 11 11 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM81988.1 - 2.9e-17 62.2 64.3 0.028 14.4 0.5 11.6 11 0 0 11 11 11 9 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM81988.1 - 6.8e-16 57.7 74.9 0.015 15.0 1.4 12.3 12 0 0 12 12 12 9 C2H2-type zinc-finger domain GAGA PF09237.11 KFM81988.1 - 1.4e-07 31.2 27.6 0.2 11.5 0.6 8.1 2 2 8 10 10 10 5 GAGA factor zf-C2HC_2 PF13913.6 KFM81988.1 - 2.4e-07 30.5 43.6 2.4 8.1 0.1 10.7 10 0 0 10 10 10 2 zinc-finger of a C2HC-type DUF4825 PF16107.5 KFM81988.1 - 4.4e-07 30.0 0.1 8.1 6.6 0.0 5.9 4 2 3 7 7 6 0 Domain of unknown function (DUF4825) zf-Sec23_Sec24 PF04810.15 KFM81988.1 - 1.2e-06 28.4 39.5 1.2 9.2 0.1 10.1 8 3 2 10 10 10 3 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM81988.1 - 6.4e-05 23.0 50.7 7.4 6.8 0.4 11.2 11 0 0 11 11 11 0 DBF zinc finger zf-MYST PF17772.1 KFM81988.1 - 0.00021 20.8 59.3 0.3 10.7 0.2 10.8 2 2 9 11 11 11 4 MYST family zinc finger domain BolA PF01722.18 KFM81988.1 - 0.00025 21.3 19.4 1.1 9.6 0.4 7.1 1 1 6 7 7 7 1 BolA-like protein C1_1 PF00130.22 KFM81988.1 - 0.00033 20.5 57.7 0.51 10.3 3.7 9.2 3 3 4 8 8 8 2 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KFM81988.1 - 0.00037 20.4 31.9 0.42 10.6 0.4 7.2 3 2 4 8 8 8 2 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM81988.1 - 0.00044 20.4 1.3 2.1 8.5 0.1 3.5 2 1 1 3 3 3 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_2 PF12756.7 KFM81988.1 - 0.00044 20.5 76.7 0.8 10.1 0.8 10.8 1 1 10 11 11 11 5 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 KFM81988.1 - 0.0019 18.3 47.5 0.055 13.6 5.0 4.8 1 1 4 5 5 5 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_9 PF16293.5 KFM81988.1 - 0.002 17.9 49.0 3.6 7.5 0.2 10.6 2 2 9 11 11 11 2 C2H2 type zinc-finger (1 copy) DUF952 PF06108.12 KFM81988.1 - 0.0057 16.6 0.2 31 4.7 0.0 4.7 2 2 2 4 4 4 0 Protein of unknown function (DUF952) KptA_kDCL PF18176.1 KFM81988.1 - 0.02 14.8 2.1 11 5.9 0.2 4.1 1 1 0 3 3 3 0 KptA in kinetoplastid DICER domain Mga PF05043.13 KFM81988.1 - 0.2 12.3 2.0 31 5.2 0.2 3.7 3 1 0 3 3 3 0 Mga helix-turn-helix domain FYVE PF01363.21 KFM81988.1 - 0.33 11.1 55.2 0.12 12.5 7.2 5.6 1 1 3 4 4 3 0 FYVE zinc finger DUF2256 PF10013.9 KFM81988.1 - 0.8 9.9 42.0 17 5.6 0.1 10.4 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) Zf_RING PF16744.5 KFM81988.1 - 1.9 8.6 54.9 19 5.5 0.5 9.7 1 1 3 7 7 7 0 KIAA1045 RING finger Zn-ribbon_8 PF09723.10 KFM81988.1 - 3.4 7.9 46.7 1.8 8.8 0.6 6.8 6 2 1 7 7 7 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 KFM81988.1 - 7.8 6.9 54.1 0.43 10.9 3.6 6.1 1 1 6 7 7 7 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFM81988.1 - 8.8 7.2 48.4 2.1 9.1 1.9 5.9 1 1 3 5 5 5 0 zinc-ribbon family IF-2B PF01008.17 KFM81989.1 - 1.5e-82 277.0 0.2 1.5e-82 277.0 0.2 2.2 2 0 0 2 2 2 1 Initiation factor 2 subunit family Dimer_Tnp_hAT PF05699.14 KFM81990.1 - 0.00067 19.4 0.2 0.00074 19.3 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Col_cuticle_N PF01484.17 KFM81990.1 - 0.042 13.9 0.2 0.081 13.0 0.0 1.5 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain WD40 PF00400.32 KFM81993.1 - 1.6e-10 41.4 5.4 5.2e-05 23.9 2.2 2.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM81993.1 - 8.4e-09 35.6 0.1 0.00074 19.8 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KFM81993.1 - 1.9e-05 23.2 0.1 2.4e-05 22.9 0.1 1.0 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KFM81993.1 - 0.018 14.0 0.1 0.095 11.6 0.0 1.8 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KFM81994.1 - 0.0097 16.7 1.3 0.26 12.2 0.1 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat MULE PF10551.9 KFM81995.1 - 1.1e-16 61.0 3.6 1.6e-16 60.5 0.6 2.7 3 0 0 3 3 3 1 MULE transposase domain MMS22L_C PF14911.6 KFM81995.1 - 0.046 12.8 0.1 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal PatG_C PF18065.1 KFM81995.1 - 0.057 13.4 0.1 3.8 7.5 0.0 2.3 2 0 0 2 2 2 0 PatG C-terminal TPR_22 PF18833.1 KFM81995.1 - 0.32 11.2 1.3 2.1 8.5 0.3 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Spore_III_AB PF09548.10 KFM81996.1 - 0.078 13.1 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Pkinase PF00069.25 KFM81997.1 - 4.9e-69 232.6 0.0 6e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM81997.1 - 5e-24 85.0 0.0 6.8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM81997.1 - 1.8e-07 30.8 0.0 1.4e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 KFM81997.1 - 0.0015 18.5 0.0 0.0043 17.0 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM81997.1 - 0.0041 16.5 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFM81997.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KFM81997.1 - 0.058 13.0 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 HSP70 PF00012.20 KFM81998.1 - 1e-95 321.2 20.3 8.7e-94 314.8 6.4 3.0 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KFM81998.1 - 0.0003 19.7 0.1 0.022 13.6 0.0 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KFM81998.1 - 0.029 14.1 0.1 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain PH PF00169.29 KFM81999.1 - 0.0007 20.1 0.0 0.00099 19.6 0.0 1.3 1 0 0 1 1 1 1 PH domain DUF3662 PF12401.8 KFM81999.1 - 0.09 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) PI-PLC-Y PF00387.19 KFM82000.1 - 8.9e-20 71.2 0.5 9.4e-20 71.1 0.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Ion_trans PF00520.31 KFM82002.1 - 2.7e-28 98.9 8.0 2.7e-28 98.9 8.0 2.3 1 1 1 2 2 2 1 Ion transport protein TRP_2 PF08344.11 KFM82002.1 - 1.5e-26 92.4 5.1 3.3e-26 91.3 5.1 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 KFM82002.1 - 2e-10 41.1 4.8 3.2e-07 30.8 0.7 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PKD_channel PF08016.12 KFM82002.1 - 2.9e-10 39.4 8.8 2.1e-05 23.4 0.4 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ank_4 PF13637.6 KFM82002.1 - 0.00013 22.4 0.8 0.059 14.0 0.2 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM82002.1 - 0.00038 20.7 4.7 0.32 11.7 0.0 4.3 3 1 1 4 4 4 1 Ankyrin repeat Ank PF00023.30 KFM82002.1 - 0.0022 18.4 0.5 0.071 13.6 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KFM82002.1 - 0.003 17.8 0.1 0.24 11.8 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) F-box PF00646.33 KFM82003.1 - 5.7e-09 35.6 0.2 1.4e-08 34.4 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFM82003.1 - 1.2e-08 34.7 0.1 2.8e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like zf-RING_10 PF16685.5 KFM82006.1 - 1.8e-25 88.9 15.7 1.8e-25 88.9 15.7 2.8 3 0 0 3 3 3 1 zinc RING finger of MSL2 MSL2-CXC PF16682.5 KFM82006.1 - 4.2e-17 62.0 21.3 4.2e-17 62.0 21.3 3.0 3 0 0 3 3 3 1 CXC domain of E3 ubiquitin-protein ligase MSL2 Otopetrin PF03189.13 KFM82007.1 - 1.4e-96 324.1 16.3 6.7e-96 321.8 13.9 2.6 2 1 0 2 2 2 1 Otopetrin TMEM192 PF14802.6 KFM82007.1 - 0.0024 17.0 12.5 0.058 12.5 0.4 3.2 3 0 0 3 3 3 2 TMEM192 family TatC PF00902.18 KFM82007.1 - 0.63 9.8 10.3 0.44 10.3 7.7 2.1 1 1 1 2 2 2 0 Sec-independent protein translocase protein (TatC) TRP_2 PF08344.11 KFM82009.1 - 3.5e-27 94.4 2.3 5.9e-27 93.7 2.3 1.4 1 0 0 1 1 1 1 Transient receptor ion channel II Ank PF00023.30 KFM82009.1 - 2.3e-05 24.6 0.1 7.2e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KFM82009.1 - 0.00094 19.5 0.1 0.0034 17.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KFM82009.1 - 0.0012 19.4 0.0 0.0067 17.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM82009.1 - 0.0076 16.5 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM82009.1 - 0.036 14.7 0.1 0.13 12.9 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ion_trans PF00520.31 KFM82010.1 - 6.5e-18 64.8 7.9 1e-17 64.2 7.9 1.3 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM82010.1 - 3.1e-10 39.3 1.1 3.9e-10 39.0 1.1 1.1 1 0 0 1 1 1 1 Polycystin cation channel MPS-4 PF17523.2 KFM82010.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.4 3 0 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DEAD PF00270.29 KFM82011.1 - 1.2e-43 149.0 0.1 1.8e-43 148.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM82011.1 - 6e-09 36.1 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFM82011.1 - 0.0069 16.7 0.5 0.028 14.7 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFM82011.1 - 0.025 14.8 0.5 0.25 11.6 0.5 2.4 1 1 0 1 1 1 0 AAA domain UTP25 PF06862.12 KFM82011.1 - 0.039 12.7 0.4 1.3 7.8 0.1 2.4 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF2075 PF09848.9 KFM82011.1 - 0.065 12.5 0.0 0.56 9.4 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF4217 PF13959.6 KFM82012.1 - 9.9e-21 73.7 1.7 2.4e-20 72.5 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4217) Anthrax_toxA PF03497.16 KFM82012.1 - 0.027 14.6 2.1 0.061 13.4 2.1 1.5 1 0 0 1 1 1 0 Anthrax toxin LF subunit CHORD PF04968.12 KFM82013.1 - 2.4e-51 172.3 24.6 6e-26 90.9 5.9 2.8 3 0 0 3 3 3 2 CHORD CS PF04969.16 KFM82013.1 - 1e-11 45.7 0.1 2e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 CS domain Robl_LC7 PF03259.17 KFM82014.1 - 4.1e-15 55.3 0.1 4.9e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain CK_II_beta PF01214.18 KFM82016.1 - 5.9e-84 280.4 0.0 6.8e-84 280.2 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 KFM82016.1 - 0.075 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Collagen PF01391.18 KFM82017.1 - 2.6e-95 312.2 332.7 1e-10 41.2 26.4 13.8 2 2 11 13 13 13 13 Collagen triple helix repeat (20 copies) Collagen PF01391.18 KFM82018.1 - 1e-54 182.1 153.8 1.8e-10 40.4 22.0 7.0 1 1 5 6 6 6 6 Collagen triple helix repeat (20 copies) C4 PF01413.19 KFM82019.1 - 2.3e-85 282.3 3.9 1.1e-45 154.6 0.1 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen SPRY PF00622.28 KFM82020.1 - 3.1e-18 66.0 0.0 4.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain F-box PF00646.33 KFM82020.1 - 8.6e-10 38.3 0.6 2.4e-09 36.8 0.4 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFM82020.1 - 6.7e-09 35.5 1.0 1.5e-08 34.3 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KFM82020.1 - 0.00041 19.8 0.0 0.00088 18.8 0.0 1.5 1 0 0 1 1 1 1 F-box Exonuc_X-T_C PF08411.10 KFM82020.1 - 0.044 12.9 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Exonuclease C-terminal Neuralized PF07177.12 KFM82020.1 - 0.16 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Neuralized Dpoe2NT PF12213.8 KFM82021.1 - 3e-20 72.3 0.4 1e-19 70.6 0.2 1.8 2 0 0 2 2 2 1 DNA polymerases epsilon N terminal DUF5065 PF16723.5 KFM82021.1 - 0.1 12.7 0.1 0.25 11.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DNA_pol_E_B PF04042.16 KFM82022.1 - 3.7e-16 59.1 0.1 4.1e-16 59.0 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_E_B PF04042.16 KFM82023.1 - 8.3e-10 38.4 0.1 8.6e-10 38.3 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DapH_N PF08503.10 KFM82024.1 - 3 8.1 11.1 0.058 13.6 1.7 3.1 3 0 0 3 3 3 0 Tetrahydrodipicolinate succinyltransferase N-terminal Pkinase_Tyr PF07714.17 KFM82025.1 - 1.6e-99 332.4 0.0 4.2e-99 331.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFM82025.1 - 1.8e-40 139.0 0.0 3.9e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFM82025.1 - 9.7e-36 122.0 21.0 3.7e-13 49.6 0.8 6.9 6 0 0 6 6 6 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM82025.1 - 5e-14 52.7 8.7 1.1e-05 25.9 0.3 5.1 4 0 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFM82025.1 - 4.8e-07 30.1 6.4 0.24 11.7 0.0 5.0 4 0 0 4 4 4 3 Interferon-alpha/beta receptor, fibronectin type III Ldl_recept_b PF00058.17 KFM82025.1 - 5.2e-05 23.6 2.4 1 9.9 0.0 7.0 8 0 0 8 8 8 1 Low-density lipoprotein receptor repeat class B Insulin_TMD PF17870.1 KFM82025.1 - 0.047 13.8 1.4 0.11 12.6 1.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment fn3 PF00041.21 KFM82027.1 - 2.2e-08 34.3 1.7 0.003 17.9 0.1 2.2 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM82027.1 - 0.014 16.0 0.3 1.7 9.3 0.2 2.3 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain MFS_1 PF07690.16 KFM82029.1 - 4.2e-43 147.6 34.0 5e-43 147.4 34.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM82029.1 - 4.2e-07 29.2 25.5 8.4e-07 28.2 15.7 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter Spectrin PF00435.21 KFM82030.1 - 6e-160 521.7 141.8 2.5e-19 69.7 0.8 12.2 12 0 0 12 12 12 12 Spectrin repeat PH_9 PF15410.6 KFM82030.1 - 0.0041 17.5 0.4 0.077 13.4 0.0 3.1 2 0 0 2 2 2 1 Pleckstrin homology domain DUF2122 PF09895.9 KFM82030.1 - 0.031 14.7 1.4 2.8 8.4 0.1 3.1 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) NPV_P10 PF05531.12 KFM82030.1 - 0.51 10.8 0.0 0.51 10.8 0.0 10.7 10 1 1 11 11 11 0 Nucleopolyhedrovirus P10 protein HGD-D PF06050.13 KFM82030.1 - 0.56 9.9 7.5 0.28 10.9 2.9 2.8 1 1 1 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component PH PF00169.29 KFM82030.1 - 1.2 9.7 5.2 0.56 10.8 0.3 3.0 3 0 0 3 3 3 0 PH domain CH PF00307.31 KFM82031.1 - 1.5e-43 147.4 5.1 6.2e-22 77.8 0.0 4.2 5 0 0 5 5 5 2 Calponin homology (CH) domain Spectrin PF00435.21 KFM82031.1 - 3.4e-43 146.4 62.3 3.7e-11 43.4 2.3 8.6 7 1 1 8 8 8 7 Spectrin repeat CAMSAP_CH PF11971.8 KFM82031.1 - 8.2e-07 28.8 1.2 2.3e-05 24.2 0.0 3.4 3 0 0 3 3 3 1 CAMSAP CH domain CH_2 PF06294.11 KFM82031.1 - 0.016 15.3 0.2 10 6.3 0.0 4.3 4 0 0 4 4 4 0 CH-like domain in sperm protein DUF948 PF06103.11 KFM82031.1 - 0.94 9.8 5.0 65 3.9 0.3 4.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Peptidase_A17 PF05380.13 KFM82032.1 - 3.2e-28 98.8 0.1 5.2e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase HNF-1_N PF04814.13 KFM82033.1 - 2.4e-09 38.1 0.0 3e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 KFM82034.1 - 1.2e-09 37.8 0.6 4.5e-09 36.0 0.6 2.0 1 1 0 1 1 1 1 Homeodomain HNF-1_N PF04814.13 KFM82034.1 - 3e-08 34.5 1.1 7.2e-08 33.3 0.0 2.1 2 1 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox_KN PF05920.11 KFM82034.1 - 0.00069 19.5 0.3 0.0022 17.9 0.2 1.8 2 0 0 2 2 2 1 Homeobox KN domain HTH_3 PF01381.22 KFM82034.1 - 0.00086 19.3 0.0 0.0038 17.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix HTH_37 PF13744.6 KFM82034.1 - 0.028 14.4 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MGAT2 PF05060.14 KFM82036.1 - 7.3e-156 518.6 6.4 8.6e-156 518.4 6.4 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Exo_endo_phos PF03372.23 KFM82038.1 - 1.2e-15 57.7 0.0 1.4e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_29 PF13551.6 KFM82039.1 - 0.0044 17.0 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 KFM82039.1 - 0.011 16.3 0.0 0.016 15.8 0.0 1.2 1 1 0 1 1 1 0 Homeodomain-like domain HTH_48 PF17906.1 KFM82039.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain in Mos1 transposase DDE_Tnp_1_7 PF13843.6 KFM82040.1 - 3.3e-75 253.6 2.5 4e-75 253.3 2.5 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 KFM82040.1 - 0.057 14.2 6.5 0.13 13.0 6.5 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF2497 PF10691.9 KFM82041.1 - 0.21 12.0 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) adh_short PF00106.25 KFM82042.1 - 3.5e-33 114.7 0.1 4e-33 114.5 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM82042.1 - 9.7e-17 61.3 0.0 1.2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM82042.1 - 2.7e-05 24.2 0.0 5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KFM82042.1 - 0.01 16.4 0.1 0.016 15.7 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KFM82042.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 KFM82042.1 - 0.067 12.6 0.0 0.079 12.4 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TAL_FSA PF00923.19 KFM82043.1 - 3.8e-100 334.9 0.1 4.3e-100 334.8 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Cyt-b5 PF00173.28 KFM82044.1 - 1.2e-11 44.6 0.1 1.7e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DDE_1 PF03184.19 KFM82045.1 - 3.4e-21 75.7 0.1 3.7e-21 75.6 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease SAM_3 PF18016.1 KFM82045.1 - 0.015 15.0 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) zf-CCCH PF00642.24 KFM82046.1 - 6.3e-06 26.0 11.6 0.0019 18.1 3.9 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFM82046.1 - 0.00066 19.9 4.8 0.0039 17.4 4.8 2.3 1 1 0 1 1 1 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 KFM82046.1 - 0.0042 17.1 15.5 0.017 15.2 1.7 3.5 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFM82046.1 - 0.23 11.3 11.8 0.66 9.8 0.8 3.1 2 1 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 KFM82046.1 - 0.24 12.1 7.0 5.5 7.7 0.4 2.7 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 KFM82046.1 - 0.47 11.0 15.5 1.3 9.6 2.2 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF4603 PF15376.6 KFM82047.1 - 2.4e-20 71.7 1.9 9.4e-20 69.7 1.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4603) CRAL_TRIO PF00650.20 KFM82048.1 - 1.3e-29 103.0 0.0 2.2e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM82048.1 - 5.1e-05 23.4 1.2 0.00017 21.7 1.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFM82048.1 - 0.0014 18.8 1.6 0.0027 17.9 0.1 2.1 1 1 1 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM82049.1 - 4.7e-09 36.1 0.0 3e-08 33.5 0.0 2.0 1 1 2 3 3 3 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM82049.1 - 4.8e-07 29.9 0.4 7.4e-07 29.3 0.4 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 KFM82050.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 CRAL/TRIO domain SET PF00856.28 KFM82051.1 - 4.8e-07 30.3 0.0 8.6e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 SET domain DDE_3 PF13358.6 KFM82053.1 - 0.022 14.5 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease TFIID-18kDa PF02269.16 KFM82054.1 - 2.9e-36 123.4 0.4 3.7e-36 123.0 0.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Ig_3 PF13927.6 KFM82055.1 - 2.5e-72 239.5 0.0 1.9e-13 50.8 0.0 6.3 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFM82055.1 - 3.4e-65 216.1 0.0 4.2e-14 52.4 0.0 6.8 6 1 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFM82055.1 - 1.6e-48 162.9 0.1 2.9e-09 37.1 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFM82055.1 - 2.6e-41 139.7 0.0 7.5e-07 29.2 0.0 6.4 6 1 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 KFM82055.1 - 1.3e-26 92.9 6.5 0.0018 18.4 0.0 9.6 5 5 2 7 7 7 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM82055.1 - 9.8e-15 54.4 0.0 0.086 12.9 0.0 6.2 6 0 0 6 6 6 4 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFM82055.1 - 1.7e-07 31.2 0.2 0.32 11.1 0.0 5.5 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFM82055.1 - 1.6e-06 27.6 0.0 0.09 12.4 0.0 3.9 4 0 0 4 4 4 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM82055.1 - 2e-05 24.5 0.3 1.3 9.1 0.0 5.2 6 1 0 6 6 6 1 C17orf99 Ig domain Ig_5 PF16681.5 KFM82055.1 - 2.2e-05 24.8 0.0 9.2 6.8 0.0 5.3 5 1 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFM82055.1 - 8.4e-05 22.8 0.0 6.3 7.1 0.0 5.0 5 1 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFM82055.1 - 0.00014 22.1 0.0 0.84 10.1 0.1 4.5 4 0 0 4 4 4 1 Immunoglobulin C1-set domain CBM_5_12 PF02839.14 KFM82055.1 - 0.098 13.3 0.8 1 10.1 0.7 2.8 3 0 0 3 3 3 0 Carbohydrate binding domain Ig_3 PF13927.6 KFM82056.1 - 2.1e-44 150.0 0.3 6.2e-15 55.6 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 KFM82056.1 - 7.5e-42 141.3 0.0 7e-13 48.5 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain ig PF00047.25 KFM82056.1 - 2.4e-28 98.1 0.0 2.5e-09 37.2 0.0 3.8 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 KFM82056.1 - 7.6e-28 96.7 0.0 2e-09 37.6 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFM82056.1 - 1.8e-18 66.7 0.5 1.6e-06 28.3 0.0 6.1 4 3 0 4 4 4 3 Immunoglobulin V-set domain fn3 PF00041.21 KFM82056.1 - 1.7e-15 57.1 0.1 1e-14 54.6 0.0 2.3 3 0 0 3 3 2 1 Fibronectin type III domain C2-set_2 PF08205.12 KFM82056.1 - 4.6e-10 39.4 0.0 0.018 15.1 0.0 4.3 3 2 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM82056.1 - 4e-07 29.5 0.2 0.023 14.3 0.0 4.0 4 0 0 4 4 4 2 Immunoglobulin domain Ig_5 PF16681.5 KFM82056.1 - 1.3e-06 28.8 0.0 0.16 12.4 0.0 4.3 3 3 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.5 KFM82056.1 - 0.00037 21.0 0.0 0.0017 18.9 0.0 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Receptor_2B4 PF11465.8 KFM82056.1 - 0.001 19.2 0.0 0.097 12.9 0.0 2.8 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Ig_4 PF16680.5 KFM82056.1 - 0.0039 17.4 0.0 4.5 7.6 0.0 4.0 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFM82056.1 - 0.0071 16.4 0.0 4 7.6 0.0 2.7 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFM82056.1 - 0.012 15.7 0.5 1.4 9.0 0.0 4.1 5 2 0 5 5 4 0 C17orf99 Ig domain V-set_CD47 PF08204.11 KFM82056.1 - 0.012 15.6 0.0 0.7 9.9 0.0 2.8 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain Tissue_fac PF01108.17 KFM82056.1 - 0.013 15.3 0.0 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 Tissue factor SusE PF14292.6 KFM82056.1 - 0.068 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 SusE outer membrane protein fn3 PF00041.21 KFM82057.1 - 2.7e-43 146.2 2.3 6.1e-11 42.5 0.0 4.6 4 0 0 4 4 4 4 Fibronectin type III domain I-set PF07679.16 KFM82057.1 - 1.1e-13 51.0 0.0 3.8e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM82057.1 - 7.1e-11 42.6 0.0 3.8e-10 40.2 0.0 2.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM82057.1 - 2.5e-08 34.2 0.0 6.6e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM82057.1 - 2.9e-06 27.4 0.0 1.1e-05 25.5 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain fn3_2 PF16893.5 KFM82057.1 - 0.00044 20.4 0.1 0.036 14.2 0.0 3.0 3 0 0 3 3 3 1 Fibronectin type III domain V-set PF07686.17 KFM82057.1 - 0.0011 19.2 0.0 0.0084 16.3 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM82057.1 - 0.023 14.3 0.0 0.15 11.7 0.0 2.3 3 0 0 3 3 3 0 Immunoglobulin domain FAM76 PF16046.5 KFM82057.1 - 0.37 10.1 1.1 0.7 9.2 1.1 1.4 1 0 0 1 1 1 0 FAM76 protein Shisa PF13908.6 KFM82057.1 - 1.2 9.3 6.7 0.12 12.6 1.1 2.2 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator zf-C3HC4_3 PF13920.6 KFM82058.1 - 1.4e-06 28.1 12.6 1.6e-06 27.9 12.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM82058.1 - 0.00048 20.4 10.2 0.00048 20.4 10.2 1.3 2 0 0 2 2 2 1 Ring finger domain zf-P11 PF03854.14 KFM82058.1 - 0.015 14.9 10.2 0.015 14.9 10.2 1.1 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_2 PF13923.6 KFM82058.1 - 0.021 14.7 10.7 0.021 14.7 10.7 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM82058.1 - 0.027 14.4 9.5 0.027 14.4 9.5 1.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM82059.1 - 7.3e-08 32.1 12.4 1.1e-07 31.6 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM82059.1 - 0.00083 19.6 14.0 0.0015 18.8 14.0 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFM82059.1 - 0.0011 18.8 11.8 0.0018 18.1 11.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 KFM82059.1 - 0.06 13.0 10.7 0.1 12.3 10.7 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_2 PF13923.6 KFM82059.1 - 0.22 11.4 15.1 0.39 10.6 15.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ORC6 PF05460.13 KFM82059.1 - 0.87 8.8 9.3 0.99 8.6 8.2 1.4 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) zf-RING_4 PF14570.6 KFM82059.1 - 3.1 7.7 13.3 13 5.6 13.5 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PRE_C2HC PF07530.11 KFM82060.1 - 0.00042 20.4 0.1 0.0017 18.4 0.0 2.0 2 0 0 2 2 2 1 Associated with zinc fingers DDE_3 PF13358.6 KFM82060.1 - 0.011 15.4 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Cystatin PF00031.21 KFM82061.1 - 6.3e-05 23.2 0.0 7.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain WD40_alt PF14077.6 KFM82062.1 - 0.021 14.7 0.2 0.036 13.9 0.2 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Sugar_tr PF00083.24 KFM82064.1 - 0.011 14.7 0.1 0.022 13.7 0.0 1.5 1 1 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.16 KFM82064.1 - 0.011 14.6 0.2 0.02 13.8 0.0 1.5 2 1 1 3 3 3 0 Major Facilitator Superfamily ocr PF08684.10 KFM82065.1 - 0.0054 17.2 0.3 0.0071 16.8 0.3 1.2 1 0 0 1 1 1 1 DNA mimic ocr DUF1298 PF06974.13 KFM82065.1 - 0.14 12.1 0.2 0.24 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) RET_CLD3 PF17812.1 KFM82065.1 - 0.36 11.1 5.8 0.74 10.1 4.7 1.9 1 1 0 1 1 1 0 RET Cadherin like domain 3 SNAD2 PF18745.1 KFM82066.1 - 0.0077 16.0 0.4 0.014 15.1 0.4 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 2 p450 PF00067.22 KFM82067.1 - 4e-79 266.5 0.1 4.8e-79 266.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 EntA_Immun PF08951.10 KFM82067.1 - 0.097 13.0 0.8 1.6 9.1 0.3 3.0 3 0 0 3 3 3 0 Enterocin A Immunity PH PF00169.29 KFM82068.1 - 9.1e-07 29.4 0.4 2.7e-06 27.8 0.4 1.9 1 0 0 1 1 1 1 PH domain MRP-S26 PF14943.6 KFM82070.1 - 1.5e-41 142.1 13.8 2.2e-41 141.6 13.8 1.2 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 DUF3991 PF13154.6 KFM82070.1 - 0.31 11.4 2.2 0.47 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) DUF2252 PF10009.9 KFM82070.1 - 0.74 8.8 6.0 1 8.4 6.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Caldesmon PF02029.15 KFM82070.1 - 5.6 5.6 20.9 7.3 5.2 20.9 1.1 1 0 0 1 1 1 0 Caldesmon NusG PF02357.19 KFM82071.1 - 0.053 14.0 0.0 0.064 13.8 0.0 1.2 1 0 0 1 1 1 0 Transcription termination factor nusG WD40 PF00400.32 KFM82072.1 - 1.2e-09 38.6 0.1 0.0007 20.3 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM82072.1 - 0.00095 19.4 0.0 0.11 12.8 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KFM82072.1 - 0.004 16.9 0.1 0.011 15.5 0.5 1.6 2 1 0 2 2 2 1 TUP1-like enhancer of split Nup160 PF11715.8 KFM82072.1 - 0.011 14.4 0.0 0.37 9.4 0.2 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFM82072.1 - 0.094 11.7 0.0 0.37 9.7 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4506 PF14958.6 KFM82073.1 - 6.7e-18 64.6 0.4 1.7e-17 63.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4506) Tsp45I PF06300.12 KFM82073.1 - 0.018 14.6 0.4 0.036 13.6 0.4 1.5 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme DUF2498 PF10692.9 KFM82073.1 - 0.13 12.2 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) PPTA PF01239.22 KFM82074.1 - 1.3e-49 164.5 17.0 1e-11 44.2 1.5 6.0 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 KFM82074.1 - 6.2 6.6 15.0 15 5.4 0.3 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) AAA_34 PF13872.6 KFM82075.1 - 3.1e-145 482.7 0.0 5.1e-145 482.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 KFM82075.1 - 1.1e-121 405.7 0.0 1.6e-121 405.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 KFM82075.1 - 2.3e-07 31.0 0.0 2.8e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFM82075.1 - 0.019 15.3 0.0 0.063 13.6 0.0 2.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain YL1 PF05764.13 KFM82075.1 - 4.1 7.4 8.9 0.43 10.6 4.0 1.8 2 0 0 2 2 2 0 YL1 nuclear protein SPATA1_C PF15743.5 KFM82076.1 - 0.0002 21.4 11.2 0.0002 21.4 11.2 1.6 2 0 0 2 2 2 1 Spermatogenesis-associated C-terminus LRR_8 PF13855.6 KFM82077.1 - 0.091 12.5 1.3 0.55 10.0 0.7 2.3 1 1 1 2 2 2 0 Leucine rich repeat Ank_2 PF12796.7 KFM82079.1 - 1.3e-05 25.6 0.1 1.7e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM82079.1 - 0.00035 20.8 0.1 0.0023 18.2 0.2 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM82079.1 - 0.00049 20.6 0.2 0.00079 20.0 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM82079.1 - 0.0015 18.9 1.0 1.1 10.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KFM82079.1 - 0.0021 18.4 2.9 1.2 9.8 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Gal-bind_lectin PF00337.22 KFM82080.1 - 1e-64 216.1 0.0 2.7e-34 117.6 0.0 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin zf-C2HC_2 PF13913.6 KFM82081.1 - 5.8e-11 42.0 17.0 7.8e-10 38.4 2.1 3.4 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KFM82081.1 - 0.024 15.4 0.9 0.024 15.4 0.9 4.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM82081.1 - 0.024 15.1 0.2 0.024 15.1 0.2 4.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type Adeno_VII PF03228.14 KFM82081.1 - 0.083 13.5 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 Adenoviral core protein VII UBZ_FAAP20 PF15750.5 KFM82081.1 - 0.95 9.5 6.8 2.7 8.0 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger DZR PF12773.7 KFM82081.1 - 1.6 8.8 16.8 0.64 10.1 5.7 3.5 3 0 0 3 3 3 0 Double zinc ribbon FYVE PF01363.21 KFM82081.1 - 4 7.6 12.5 1.2 9.3 0.1 3.4 3 0 0 3 3 3 0 FYVE zinc finger RhoGEF PF00621.20 KFM82083.1 - 4.3e-17 62.9 3.6 4.3e-17 62.9 3.6 2.5 2 1 0 2 2 2 1 RhoGEF domain FA PF08736.11 KFM82083.1 - 1.1e-13 51.0 8.1 3e-13 49.6 8.1 1.9 1 0 0 1 1 1 1 FERM adjacent (FA) PH PF00169.29 KFM82084.1 - 9.7e-07 29.3 0.0 1.9e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KFM82084.1 - 3.8e-05 23.7 0.1 6.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 PH domain Fib_alpha PF08702.10 KFM82084.1 - 0.0048 17.1 0.6 0.0064 16.7 0.6 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Ribosomal_L29e PF01779.17 KFM82084.1 - 0.037 14.4 0.3 0.037 14.4 0.3 2.6 3 0 0 3 3 3 0 Ribosomal L29e protein family PH PF00169.29 KFM82085.1 - 7.3e-10 39.3 0.1 8.1e-10 39.2 0.1 1.0 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFM82085.1 - 0.0017 18.7 1.9 0.14 12.5 0.5 2.1 1 1 0 2 2 2 2 Pleckstrin homology domain SSrecog PF03531.14 KFM82085.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) zf-CCCH PF00642.24 KFM82086.1 - 3.5e-10 39.5 18.4 0.0006 19.7 1.0 4.5 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFM82086.1 - 0.00012 22.2 13.2 0.21 11.8 0.7 3.2 2 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFM82086.1 - 0.0061 17.0 29.4 0.21 12.1 2.0 4.3 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KFM82086.1 - 0.051 14.3 17.0 0.32 11.7 0.5 4.2 2 2 2 4 4 4 0 Torus domain ATXN-1_C PF12547.8 KFM82086.1 - 0.064 13.6 1.1 11 6.5 0.0 4.0 4 1 0 4 4 4 0 Capicua transcriptional repressor modulator zf-CCCH_4 PF18044.1 KFM82086.1 - 1.7 8.5 34.5 0.17 11.7 3.5 5.3 4 3 0 4 4 4 0 CCCH-type zinc finger A2M PF00207.22 KFM82087.1 - 1.7e-24 85.5 0.0 2.9e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 KFM82087.1 - 3.8e-18 66.2 0.0 7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain ANATO PF01821.18 KFM82087.1 - 1.1e-07 32.5 4.4 1.1e-07 32.5 4.4 2.1 2 0 0 2 2 2 1 Anaphylotoxin-like domain ABC_tran PF00005.27 KFM82088.1 - 1.4e-26 93.6 0.0 2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM82088.1 - 1.6e-05 24.5 0.0 4.2e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFM82088.1 - 0.00077 19.7 0.2 0.0093 16.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 KFM82088.1 - 0.025 14.8 3.0 0.13 12.5 0.5 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KFM82088.1 - 0.03 14.9 0.3 0.056 14.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFM82088.1 - 0.047 13.0 0.0 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.20 KFM82088.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase TrkA_N PF02254.18 KFM82088.1 - 0.082 13.2 1.0 0.54 10.5 0.0 2.4 1 1 1 2 2 2 0 TrkA-N domain AAA_33 PF13671.6 KFM82088.1 - 0.1 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KFM82088.1 - 0.16 11.7 0.2 7.6 6.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3519 PF12033.8 KFM82090.1 - 0.058 13.8 0.1 0.065 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) Ca_chan_IQ PF08763.11 KFM82091.1 - 7.9e-30 102.9 0.1 1.1e-29 102.5 0.1 1.2 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KFM82091.1 - 2.2e-27 94.6 0.2 3.4e-27 94.0 0.2 1.3 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated zf-C2H2_jaz PF12171.8 KFM82093.1 - 2.5e-06 27.6 0.1 4.2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM82093.1 - 4e-05 23.9 0.2 6.6e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 KFM82093.1 - 0.065 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_2 PF12756.7 KFM82093.1 - 0.07 13.5 0.1 0.084 13.2 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DLH PF01738.18 KFM82094.1 - 0.0017 18.0 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KFM82094.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 F-box PF00646.33 KFM82095.1 - 0.1 12.5 0.2 0.25 11.3 0.2 1.7 1 1 0 1 1 1 0 F-box domain EMC3_TMCO1 PF01956.16 KFM82096.1 - 2.2e-10 40.6 0.2 2.2e-10 40.5 0.2 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like GATA PF00320.27 KFM82098.1 - 3.5e-20 71.3 13.9 2.7e-14 52.5 5.1 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFM82098.1 - 0.00021 20.7 8.1 0.01 15.3 2.0 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Prim_Zn_Ribbon PF08273.12 KFM82098.1 - 0.032 14.5 2.1 0.032 14.5 2.1 2.5 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Vps36-NZF-N PF16988.5 KFM82098.1 - 0.051 13.0 0.5 0.051 13.0 0.5 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain GPCR_chapero_1 PF11904.8 KFM82098.1 - 0.061 12.8 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF2387 PF09526.10 KFM82098.1 - 0.15 12.2 0.2 0.15 12.2 0.2 1.9 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) ArfGap PF01412.18 KFM82098.1 - 0.16 12.1 8.5 0.48 10.5 0.9 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 KFM82098.1 - 0.22 11.5 11.5 1.3 9.0 1.3 2.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-RRN7 PF11781.8 KFM82098.1 - 1.3 8.8 10.6 0.48 10.2 2.5 3.0 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5_eIF-2B PF01873.17 KFM82098.1 - 2.7 7.9 6.2 0.26 11.2 0.9 2.0 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn_Tnp_IS1595 PF12760.7 KFM82098.1 - 2.9 7.9 10.4 1.6 8.8 1.2 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Auto_anti-p27 PF06677.12 KFM82098.1 - 4.3 7.6 6.0 12 6.1 0.8 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2024 PF09630.10 KFM82099.1 - 0.071 13.0 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) GATA PF00320.27 KFM82100.1 - 1.3e-29 101.5 18.6 9.4e-15 53.9 2.8 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFM82100.1 - 4.3e-06 26.1 8.3 0.0031 17.0 2.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KFM82100.1 - 0.00026 21.0 1.6 0.096 12.8 0.3 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 KFM82100.1 - 0.0015 18.6 1.4 0.4 10.8 0.1 2.9 2 1 0 2 2 2 1 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KFM82100.1 - 0.0018 18.1 6.2 0.75 9.8 1.0 3.0 3 0 0 3 3 3 2 Putative transposase DNA-binding domain TSR PF18487.1 KFM82100.1 - 0.041 14.1 1.6 0.47 10.7 0.0 3.3 4 0 0 4 4 3 0 Thrombospondin type 1 repeat Prim_Zn_Ribbon PF08273.12 KFM82100.1 - 0.067 13.5 9.5 1.1 9.6 2.0 2.7 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase eIF-5_eIF-2B PF01873.17 KFM82100.1 - 0.13 12.1 5.5 2 8.3 0.8 2.8 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 KFM82100.1 - 0.14 12.3 5.5 1.2 9.4 0.4 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2387 PF09526.10 KFM82100.1 - 0.18 12.0 3.4 22 5.3 0.1 3.3 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) TDP43_N PF18694.1 KFM82100.1 - 0.24 11.3 0.3 6.5 6.7 0.1 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain Elf1 PF05129.13 KFM82100.1 - 0.96 9.5 6.0 3.1 7.9 0.1 2.7 2 1 1 3 3 2 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 KFM82100.1 - 1.1 8.7 10.4 4.3 6.9 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 KFM82100.1 - 1.3 9.2 9.8 8.3 6.5 0.4 3.1 2 1 1 3 3 2 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 KFM82100.1 - 4 7.3 10.1 53 3.7 2.5 4.0 3 1 1 4 4 4 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KFM82100.1 - 5.6 7.0 10.7 2.9 7.9 1.1 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain QWRF PF04484.12 KFM82100.1 - 5.9 6.5 10.6 9.7 5.8 10.6 1.4 1 0 0 1 1 1 0 QWRF family KIAA1328 PF15369.6 KFM82100.1 - 6.3 6.5 6.2 10 5.9 6.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Fungus-induced PF10917.8 KFM82101.1 - 0.12 12.7 5.5 0.33 11.3 0.6 2.2 2 0 0 2 2 2 0 Fungus-induced protein zf-ribbon_3 PF13248.6 KFM82102.1 - 0.00022 20.5 0.3 0.00068 19.0 0.3 1.9 1 0 0 1 1 1 1 zinc-ribbon domain TFIIB PF00382.19 KFM82102.1 - 0.002 18.1 0.0 0.027 14.5 0.0 2.7 3 0 0 3 3 3 1 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KFM82102.1 - 0.0033 16.9 3.4 0.0086 15.6 3.4 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2087 PF09860.9 KFM82102.1 - 0.072 13.3 0.3 0.53 10.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Mga PF05043.13 KFM82102.1 - 0.15 12.7 1.5 23 5.6 0.1 2.8 2 1 0 2 2 2 0 Mga helix-turn-helix domain DUF1394 PF07159.12 KFM82104.1 - 0.046 13.0 3.5 0.052 12.8 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) ASC PF00858.24 KFM82110.1 - 6.9e-12 45.1 0.1 7.4e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel zf-H2C2_2 PF13465.6 KFM82111.1 - 2.8e-12 46.5 24.6 1.3e-07 31.7 1.5 5.1 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM82111.1 - 7.9e-11 41.8 30.5 0.00049 20.4 1.8 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM82111.1 - 3.4e-07 30.6 31.9 0.002 18.8 0.8 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFM82111.1 - 4.3e-05 24.2 13.8 0.22 12.2 2.3 3.6 2 1 1 3 3 3 3 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KFM82111.1 - 0.1 13.0 16.3 0.24 11.9 2.8 4.0 4 0 0 4 4 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KFM82111.1 - 0.25 11.5 16.4 5.9 7.1 0.3 4.5 3 1 1 4 4 4 0 Zinc ribbon domain FYVE PF01363.21 KFM82111.1 - 0.4 10.8 18.4 2.4 8.4 12.6 2.6 1 1 1 2 2 2 0 FYVE zinc finger zf-dskA_traR PF01258.17 KFM82111.1 - 0.47 10.4 3.9 2.8 7.9 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger zf-C2H2_6 PF13912.6 KFM82111.1 - 0.49 10.5 28.2 0.051 13.6 2.3 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFM82111.1 - 0.98 10.2 11.4 2.1 9.2 0.5 2.5 1 1 0 2 2 2 0 zinc-ribbon family XPA_N PF01286.18 KFM82111.1 - 1.3 9.1 9.0 17 5.5 0.0 4.1 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_jaz PF12171.8 KFM82111.1 - 2.5 8.5 13.0 1.9 8.9 0.2 4.1 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM82111.1 - 3.3 7.6 16.1 7.2 6.5 0.2 4.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM82111.1 - 5.7 7.1 9.2 1.2e+02 2.9 0.1 3.7 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger Glutaredoxin PF00462.24 KFM82112.1 - 9.3e-14 51.4 0.1 2.3e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 KFM82112.1 - 0.00031 20.8 0.0 0.0011 19.1 0.0 1.9 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein DnaJ_CXXCXGXG PF00684.19 KFM82112.1 - 1.1 9.7 9.2 4.1 7.8 9.2 2.1 1 0 0 1 1 1 0 DnaJ central domain F-box PF00646.33 KFM82113.1 - 1.5e-06 27.9 0.0 3.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFM82113.1 - 2.3e-06 27.4 0.0 5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like SlyX PF04102.12 KFM82113.1 - 0.0014 19.2 7.5 0.0064 17.1 3.3 2.9 1 1 0 2 2 2 1 SlyX Fib_alpha PF08702.10 KFM82113.1 - 0.018 15.2 6.5 0.018 15.2 6.5 4.2 4 1 1 5 5 4 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 KFM82113.1 - 0.023 14.8 12.0 0.094 12.8 3.6 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2730 PF10805.8 KFM82113.1 - 0.32 11.1 9.0 4 7.6 1.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) ABC_tran_Xtn PF12848.7 KFM82113.1 - 0.35 10.9 3.1 1.4 9.0 3.1 2.2 1 0 0 1 1 1 0 ABC transporter Sec34 PF04136.15 KFM82113.1 - 0.6 10.0 15.6 0.092 12.6 7.5 3.1 3 1 0 3 3 3 0 Sec34-like family BLOC1_2 PF10046.9 KFM82113.1 - 0.67 10.3 12.6 1 9.7 9.3 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KFM82113.1 - 0.76 10.3 10.0 4 8.0 3.3 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PspA_IM30 PF04012.12 KFM82113.1 - 0.87 9.1 14.2 8.8 5.8 13.6 2.6 2 1 0 2 2 2 0 PspA/IM30 family Spc7 PF08317.11 KFM82113.1 - 0.89 8.4 18.1 0.055 12.3 12.3 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 KFM82113.1 - 0.94 9.8 11.4 0.71 10.2 3.5 3.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain Cep57_CLD PF14073.6 KFM82113.1 - 1.1 9.3 17.4 30 4.6 6.4 3.1 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 DUF3552 PF12072.8 KFM82113.1 - 1.3 8.4 17.5 0.36 10.2 10.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 KFM82113.1 - 2.1 7.9 9.4 0.23 11.0 4.0 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit HrpB7 PF09486.10 KFM82113.1 - 3.8 7.9 8.0 0.23 11.9 1.2 2.3 2 1 1 3 3 2 0 Bacterial type III secretion protein (HrpB7) Cep57_CLD_2 PF14197.6 KFM82113.1 - 4.8 7.3 20.4 5.9 7.1 6.4 4.1 2 1 3 5 5 5 0 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.8 KFM82113.1 - 5.7 7.0 33.0 0.2 11.6 8.9 3.9 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding Fzo_mitofusin PF04799.13 KFM82113.1 - 5.9 6.4 9.3 22 4.6 3.4 2.6 1 1 1 2 2 2 0 fzo-like conserved region Sec20 PF03908.13 KFM82113.1 - 8.5 6.4 9.2 11 6.0 3.4 2.8 1 1 1 2 2 2 0 Sec20 SSF PF00474.17 KFM82114.1 - 9.8e-10 37.9 3.6 1.3e-09 37.4 3.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Mtc PF03820.17 KFM82114.1 - 0.23 10.5 2.5 0.26 10.3 2.3 1.2 1 1 0 1 1 1 0 Tricarboxylate carrier MARVEL PF01284.23 KFM82114.1 - 0.53 10.3 10.5 1.5 8.9 5.5 2.0 1 1 1 2 2 2 0 Membrane-associating domain Maf PF02545.14 KFM82116.1 - 6.1e-06 26.2 0.0 6.7e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein GTP_EFTU PF00009.27 KFM82117.1 - 1.4e-21 76.9 0.1 1.7e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RFC1 PF08519.12 KFM82117.1 - 0.081 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain ATP_bind_3 PF01171.20 KFM82117.1 - 0.088 12.6 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 PP-loop family LepA_C PF06421.12 KFM82118.1 - 2e-31 108.3 1.0 3.8e-31 107.4 1.0 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KFM82118.1 - 3e-19 68.8 0.0 5.8e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU PF00009.27 KFM82118.1 - 4.5e-16 59.0 0.1 6.9e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFM82118.1 - 2.2e-06 27.9 0.0 5.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFM82118.1 - 8.5e-06 25.8 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 KFM82118.1 - 5.3e-05 23.0 0.0 9.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain PduV-EutP PF10662.9 KFM82118.1 - 0.082 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KFM82118.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Ras family Arf PF00025.21 KFM82118.1 - 0.29 10.6 1.0 0.39 10.1 0.1 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family RmlD_sub_bind PF04321.17 KFM82119.1 - 1.2e-65 221.4 0.0 1.4e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFM82119.1 - 9.8e-27 94.0 0.0 2e-26 93.0 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM82119.1 - 5.6e-14 52.3 0.1 7.7e-13 48.5 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFM82119.1 - 6.4e-14 51.7 0.0 4.8e-10 39.1 0.0 2.6 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KFM82119.1 - 2.4e-11 43.3 1.6 4.9e-09 35.7 0.5 2.7 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFM82119.1 - 2.6e-10 39.8 0.6 1.5e-09 37.3 0.6 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFM82119.1 - 4.4e-05 23.4 0.0 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KFM82119.1 - 0.013 15.0 0.0 0.027 13.9 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 KFM82119.1 - 0.071 13.2 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KFM82119.1 - 0.32 10.9 0.6 3.3 7.6 0.4 2.1 1 1 1 2 2 2 0 KR domain Mab-21 PF03281.14 KFM82120.1 - 2.9e-100 335.4 0.0 3.9e-100 335.0 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein BTB PF00651.31 KFM82121.1 - 2.7e-10 40.4 0.0 3.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFM82123.1 - 5.4e-05 23.4 0.1 0.00013 22.1 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Ras PF00071.22 KFM82123.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Ras PF00071.22 KFM82124.1 - 3.1e-05 23.6 0.1 6.5e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFM82124.1 - 0.00018 21.7 0.0 0.00039 20.6 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Cofilin_ADF PF00241.20 KFM82125.1 - 5.2e-22 77.9 0.0 8.6e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Gelsolin PF00626.22 KFM82125.1 - 0.045 13.7 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Gelsolin repeat Topoisom_I_N PF02919.15 KFM82125.1 - 0.4 10.1 7.2 0.16 11.4 4.2 1.8 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment SH3_9 PF14604.6 KFM82126.1 - 2.4e-16 59.3 0.3 3.9e-16 58.6 0.3 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFM82126.1 - 6.8e-13 48.0 0.3 1.2e-12 47.2 0.3 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFM82126.1 - 3.5e-10 39.4 0.0 5.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Vps8 PF12816.7 KFM82129.1 - 0.064 12.8 0.4 0.068 12.7 0.4 1.1 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 BORCS7 PF16088.5 KFM82131.1 - 1.6e-27 95.8 2.9 1.7e-27 95.7 2.9 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 Glyco_transf_92 PF01697.27 KFM82131.1 - 0.024 14.3 0.0 0.024 14.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 92 VWA_3 PF13768.6 KFM82131.1 - 0.043 13.8 0.0 0.046 13.7 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain Lectin_leg-like PF03388.13 KFM82132.1 - 2.9e-73 246.0 0.0 3.9e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFM82132.1 - 6.9e-10 39.3 0.0 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial lectin LRRC37AB_C PF14914.6 KFM82132.1 - 0.0079 16.1 2.3 0.012 15.5 2.3 1.2 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain CSG2 PF16965.5 KFM82132.1 - 0.03 13.3 0.5 0.041 12.8 0.5 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF3464 PF11947.8 KFM82132.1 - 0.048 13.4 5.6 0.086 12.6 5.6 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Tim54 PF11711.8 KFM82132.1 - 0.086 11.6 6.7 0.34 9.7 7.8 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 KFM82132.1 - 0.11 11.2 3.4 0.19 10.5 3.4 1.4 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 KFM82132.1 - 0.22 11.3 13.9 0.32 10.7 13.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spt20 PF12090.8 KFM82132.1 - 0.28 10.8 10.6 0.39 10.3 10.6 1.2 1 0 0 1 1 1 0 Spt20 family Connexin PF00029.19 KFM82132.1 - 0.44 10.3 2.2 0.66 9.7 2.2 1.2 1 0 0 1 1 1 0 Connexin Zip PF02535.22 KFM82132.1 - 0.58 9.3 1.3 0.98 8.6 1.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 KFM82132.1 - 1 9.5 6.1 1.4 9.0 6.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4820 PF16091.5 KFM82132.1 - 1 8.6 7.4 1.5 8.1 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF913 PF06025.12 KFM82132.1 - 3.4 6.5 5.3 4.8 6.1 5.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 KFM82132.1 - 4.8 6.9 11.2 7.3 6.3 11.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 KFM82132.1 - 9.6 5.5 13.2 13 5.0 13.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MADF_DNA_bdg PF10545.9 KFM82136.1 - 1.1e-15 57.7 1.1 1.1e-15 57.7 1.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 KFM82136.1 - 0.59 10.5 5.8 0.15 12.5 2.2 2.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Preseq_ALAS PF09029.10 KFM82137.1 - 0.0072 16.8 0.1 0.0094 16.4 0.1 1.2 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence GTP_EFTU PF00009.27 KFM82139.1 - 1.8e-29 102.7 1.3 1.8e-29 102.7 1.3 2.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM82139.1 - 5.2e-07 29.7 0.5 2.3e-06 27.7 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFM82139.1 - 2.6e-06 27.0 2.6 2.6e-06 27.0 2.6 3.0 2 2 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 KFM82139.1 - 8.5e-06 26.1 0.8 8.5e-06 26.1 0.8 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RIBIOP_C PF04950.12 KFM82139.1 - 0.0018 17.7 0.6 0.0071 15.8 0.4 2.1 1 1 1 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PduV-EutP PF10662.9 KFM82139.1 - 0.019 14.7 0.5 3.4 7.4 0.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4430 PF14478.6 KFM82140.1 - 0.0023 18.5 0.3 0.0047 17.5 0.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4430) Cyt-b5 PF00173.28 KFM82141.1 - 9.1e-23 80.2 0.0 1e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PaaX_C PF08223.11 KFM82141.1 - 0.071 13.4 0.0 0.078 13.3 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain I-set PF07679.16 KFM82143.1 - 0.0002 21.3 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM82143.1 - 0.00025 21.6 0.1 0.00054 20.5 0.1 1.6 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM82143.1 - 0.0003 20.9 0.2 0.0024 18.0 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM82143.1 - 0.00042 19.8 0.0 0.00087 18.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFM82143.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFM82143.1 - 0.021 15.0 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Arv1 PF04161.13 KFM82144.1 - 1.5e-35 123.2 11.0 1.7e-35 123.1 11.0 1.0 1 0 0 1 1 1 1 Arv1-like family zf-ribbon_3 PF13248.6 KFM82144.1 - 0.56 9.7 3.5 4.4 6.8 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain PL48 PF15903.5 KFM82145.1 - 1.6e-67 228.0 0.0 2.9e-67 227.1 0.0 1.4 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 RTP1_C2 PF10304.9 KFM82145.1 - 0.054 13.2 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 HEAT PF02985.22 KFM82145.1 - 0.06 13.6 1.0 9.2 6.8 0.2 3.2 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 KFM82145.1 - 0.13 12.7 0.1 0.36 11.3 0.1 1.7 1 0 0 1 1 1 0 HEAT repeats F-box-like PF12937.7 KFM82146.1 - 5.3e-16 58.3 0.3 1.1e-15 57.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM82146.1 - 6.1e-14 51.5 0.4 2.1e-13 49.8 0.4 2.0 1 0 0 1 1 1 1 F-box domain RasGEF_N_2 PF14663.6 KFM82146.1 - 0.067 13.6 0.3 0.27 11.6 0.3 2.1 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Glyoxalase PF00903.25 KFM82147.1 - 1.6e-05 25.1 0.0 0.00024 21.3 0.0 2.6 2 2 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFM82147.1 - 0.00061 20.0 0.0 0.57 10.5 0.0 3.4 3 0 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4474 PF14751.6 KFM82148.1 - 8.2 5.8 6.7 0.77 9.1 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4474) HSP70 PF00012.20 KFM82150.1 - 0.006 14.8 1.7 0.058 11.6 1.7 2.0 1 1 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.20 KFM82150.1 - 0.0069 15.9 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 KFM82150.1 - 0.037 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain SMI1_KNR4 PF09346.10 KFM82150.1 - 0.12 12.8 0.1 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) DUF872 PF05915.12 KFM82151.1 - 6.1e-21 74.7 0.5 7e-21 74.5 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Phage_holin_3_6 PF07332.11 KFM82151.1 - 0.029 14.4 0.5 0.031 14.3 0.5 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 KFM82151.1 - 0.08 11.7 0.2 0.086 11.6 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3185 PF11381.8 KFM82151.1 - 0.098 12.7 2.6 0.45 10.6 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) RAMP4 PF06624.12 KFM82151.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 ATP1G1_PLM_MAT8 PF02038.16 KFM82151.1 - 3 7.4 10.6 10 5.7 6.1 2.5 2 1 0 2 2 2 0 ATP1G1/PLM/MAT8 family Glyco_hydro_20 PF00728.22 KFM82152.1 - 5.3e-12 45.8 0.0 1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF4838 PF16126.5 KFM82152.1 - 0.0025 17.2 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) THAP PF05485.12 KFM82154.1 - 1.2e-17 64.6 4.7 1.6e-17 64.2 4.7 1.1 1 0 0 1 1 1 1 THAP domain SUB1_ProdP9 PF18213.1 KFM82155.1 - 0.072 12.9 0.1 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 SUB1 protease Prodomain ProdP9 OTU PF02338.19 KFM82157.1 - 5.2e-13 49.6 0.1 5.9e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease LAL_C2 PF18603.1 KFM82160.1 - 0.00013 22.1 0.0 0.00031 20.8 0.0 1.7 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 Protein_K PF12283.8 KFM82160.1 - 0.033 14.4 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 Bacteriophage protein K ATP-grasp_4 PF13535.6 KFM82160.1 - 0.035 13.7 0.0 0.26 10.9 0.0 2.4 1 1 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFM82160.1 - 0.096 12.2 0.0 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Porin_3 PF01459.22 KFM82161.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic porin Pyridoxal_deC PF00282.19 KFM82162.1 - 1.2e-23 83.5 0.0 1.3e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Acyl_transf_3 PF01757.22 KFM82164.1 - 1.9e-29 102.8 43.1 1.9e-29 102.8 43.1 1.4 2 0 0 2 2 2 1 Acyltransferase family Tmemb_9 PF05434.11 KFM82164.1 - 0.41 10.5 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 TMEM9 KH_1 PF00013.29 KFM82165.1 - 1.2e-38 130.8 8.2 6e-18 64.4 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFM82165.1 - 1.2e-07 31.4 6.3 0.015 15.1 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFM82165.1 - 2e-06 27.6 1.7 0.15 12.0 0.1 3.6 3 0 0 3 3 3 3 KH domain DUF4750 PF15938.5 KFM82166.1 - 1.1e-08 34.6 0.2 1.3e-08 34.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) PEPCK_N PF17297.2 KFM82167.1 - 7e-99 329.8 0.0 9e-99 329.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain PEPCK_GTP PF00821.18 KFM82167.1 - 2e-93 313.1 0.2 5.2e-57 193.3 0.1 2.1 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_GTP PF00821.18 KFM82168.1 - 1.7e-46 158.7 0.1 1.8e-46 158.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain DUF4028 PF13220.6 KFM82168.1 - 0.38 10.6 3.2 0.63 9.8 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4028) NUDIX PF00293.28 KFM82169.1 - 1.5e-06 28.2 0.0 0.21 11.7 0.0 3.2 3 0 0 3 3 3 3 NUDIX domain DUF1242 PF06842.12 KFM82170.1 - 0.041 13.7 6.3 0.19 11.5 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) MFS_1 PF07690.16 KFM82172.1 - 8.1e-07 28.3 3.9 1.2e-06 27.7 3.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFM82173.1 - 3.6e-14 52.5 29.8 3.1e-08 32.9 12.2 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.16 KFM82174.1 - 1.4e-23 83.4 27.4 2.8e-16 59.4 9.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFM82175.1 - 1.2e-31 109.9 16.5 4.1e-21 75.3 2.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Rhomboid PF01694.22 KFM82176.1 - 5.7e-25 88.1 14.1 9e-25 87.4 14.1 1.3 1 0 0 1 1 1 1 Rhomboid family CAP18_C PF12153.8 KFM82177.1 - 0.00035 20.4 0.2 0.00059 19.6 0.2 1.3 1 0 0 1 1 1 1 LPS binding domain of CAP18 (C terminal) Myb_DNA-binding PF00249.31 KFM82177.1 - 0.002 18.3 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain PEP-utilisers_N PF05524.13 KFM82177.1 - 0.036 14.2 0.2 0.065 13.4 0.2 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Ydr279_N PF17745.1 KFM82178.1 - 2.7e-10 40.3 0.1 4.6e-10 39.6 0.1 1.4 1 1 0 1 1 1 1 Ydr279p protein triple barrel domain ArnB_C PF18677.1 KFM82179.1 - 0.0055 16.8 0.2 0.0059 16.7 0.2 1.2 1 0 0 1 1 1 1 Archaellum regulatory network B, C-terminal domain Adap_comp_sub PF00928.21 KFM82180.1 - 1.7e-80 270.2 0.1 2.3e-80 269.8 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFM82180.1 - 4e-06 26.8 0.8 6.8e-06 26.1 0.8 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KFM82180.1 - 0.0081 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain LOH1CR12 PF10158.9 KFM82182.1 - 2e-44 150.8 1.6 2.7e-44 150.4 1.6 1.2 1 0 0 1 1 1 1 Tumour suppressor protein DUF1664 PF07889.12 KFM82182.1 - 0.00065 19.7 2.3 0.00099 19.1 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Terminase_4 PF05119.12 KFM82182.1 - 0.0041 17.5 0.2 0.0081 16.6 0.2 1.5 1 0 0 1 1 1 1 Phage terminase, small subunit CEP63 PF17045.5 KFM82182.1 - 0.0082 16.1 2.8 0.012 15.5 2.8 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa YcbB PF08664.10 KFM82182.1 - 0.009 16.1 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 YcbB domain NPV_P10 PF05531.12 KFM82182.1 - 0.012 16.1 0.7 0.061 13.8 0.5 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CREPT PF16566.5 KFM82182.1 - 0.02 15.1 1.1 0.028 14.6 1.1 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour TPD52 PF04201.15 KFM82182.1 - 0.024 14.2 1.9 0.04 13.5 1.9 1.3 1 0 0 1 1 1 0 Tumour protein D52 family PMEI PF04043.15 KFM82182.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor CENP-F_leu_zip PF10473.9 KFM82182.1 - 0.16 12.0 4.0 0.25 11.4 4.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAUS6_N PF14661.6 KFM82182.1 - 0.21 11.2 2.0 0.29 10.7 2.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CLIP PF12032.8 KFM82183.1 - 1.6 9.1 4.3 30 5.0 4.2 2.5 1 1 0 1 1 1 0 Regulatory CLIP domain of proteinases Ctr PF04145.15 KFM82184.1 - 0.00014 22.5 0.2 0.00019 22.1 0.2 1.2 1 0 0 1 1 1 1 Ctr copper transporter family GLTP PF08718.11 KFM82185.1 - 1.9e-40 138.6 0.0 2.9e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) SOCS_box PF07525.16 KFM82187.1 - 9.5e-06 25.9 6.3 1e-05 25.8 2.5 3.0 3 0 0 3 3 3 1 SOCS box DUF4615 PF15393.6 KFM82188.1 - 0.013 16.1 0.3 0.021 15.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) RGM_N PF06535.12 KFM82190.1 - 0.17 12.1 3.1 0.14 12.3 0.7 2.1 1 1 1 2 2 2 0 Repulsive guidance molecule (RGM) N-terminus UPF0172 PF03665.13 KFM82191.1 - 8.4e-67 224.9 2.0 9.4e-67 224.8 2.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) EamA PF00892.20 KFM82192.1 - 4e-06 27.0 8.1 4e-06 27.0 8.1 2.0 2 0 0 2 2 2 1 EamA-like transporter family TMEM234 PF10639.9 KFM82192.1 - 0.0029 17.6 2.5 0.0038 17.3 2.5 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 Chitin_bind_4 PF00379.23 KFM82193.1 - 1.7e-06 28.4 1.8 2.7e-06 27.8 1.8 1.3 1 0 0 1 1 1 1 Insect cuticle protein KRTAP PF11759.8 KFM82193.1 - 0.099 13.2 16.0 0.11 13.1 8.2 2.3 2 0 0 2 2 2 0 Keratin-associated matrix Chitin_bind_4 PF00379.23 KFM82195.1 - 1.7e-06 28.4 1.8 2.7e-06 27.8 1.8 1.3 1 0 0 1 1 1 1 Insect cuticle protein KRTAP PF11759.8 KFM82195.1 - 0.036 14.6 15.0 0.091 13.3 8.5 2.3 2 0 0 2 2 2 0 Keratin-associated matrix Chitin_bind_4 PF00379.23 KFM82197.1 - 5.1e-07 30.1 1.5 7.1e-07 29.7 1.5 1.2 1 0 0 1 1 1 1 Insect cuticle protein KRTAP PF11759.8 KFM82198.1 - 0.005 17.4 6.6 0.0057 17.2 6.6 1.1 1 0 0 1 1 1 1 Keratin-associated matrix Chitin_bind_4 PF00379.23 KFM82199.1 - 7.6e-07 29.6 1.5 1.1e-06 29.1 1.5 1.2 1 0 0 1 1 1 1 Insect cuticle protein KRTAP PF11759.8 KFM82200.1 - 0.0079 16.7 7.0 0.0079 16.7 7.0 2.3 2 0 0 2 2 2 1 Keratin-associated matrix Chitin_bind_4 PF00379.23 KFM82201.1 - 5e-07 30.1 1.5 7.3e-07 29.6 1.5 1.3 1 0 0 1 1 1 1 Insect cuticle protein KRTAP PF11759.8 KFM82202.1 - 0.034 14.7 9.8 0.034 14.7 9.8 1.7 2 0 0 2 2 2 0 Keratin-associated matrix KRTAP PF11759.8 KFM82204.1 - 0.014 15.9 8.4 0.014 15.9 8.4 2.4 2 1 0 2 2 2 0 Keratin-associated matrix Chitin_bind_4 PF00379.23 KFM82205.1 - 2.3e-06 28.0 1.6 3.9e-06 27.3 1.6 1.4 1 0 0 1 1 1 1 Insect cuticle protein Ank_4 PF13637.6 KFM82206.1 - 1.4e-11 44.7 1.1 1.3e-07 32.0 0.3 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM82206.1 - 3.7e-10 39.8 1.0 1.1e-05 25.7 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFM82206.1 - 2.2e-08 34.6 0.3 5.3e-08 33.3 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM82206.1 - 5.7e-08 32.9 1.0 0.0011 19.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM82206.1 - 3.4e-07 30.0 0.3 0.00089 19.5 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeat 7tm_1 PF00001.21 KFM82207.1 - 1.6e-16 60.4 21.5 2.1e-16 60.0 21.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFM82207.1 - 9.3e-14 51.4 23.0 1.2e-13 51.0 23.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF898 PF05987.13 KFM82207.1 - 0.0049 16.0 4.8 0.0049 16.0 4.8 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) EI24 PF07264.11 KFM82207.1 - 1.4 9.1 13.2 5.6 7.2 13.2 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Ig_3 PF13927.6 KFM82209.1 - 1.1e-34 118.9 4.2 5.3e-09 36.6 0.1 4.4 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 KFM82209.1 - 6.6e-24 83.8 0.5 2.8e-09 36.9 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin I-set domain ig PF00047.25 KFM82209.1 - 2.5e-21 75.7 6.0 6.8e-07 29.4 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFM82209.1 - 4.6e-21 74.9 2.0 3.1e-06 27.4 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.12 KFM82209.1 - 6.4e-18 64.6 1.3 1.2e-10 41.3 0.1 3.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFM82209.1 - 0.00011 22.5 0.1 0.012 16.0 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin C1-set domain fn3 PF00041.21 KFM82209.1 - 0.00037 20.8 0.0 0.00096 19.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain V-set PF07686.17 KFM82209.1 - 0.0013 18.9 1.3 1.7 8.9 0.2 4.1 4 1 0 4 4 4 1 Immunoglobulin V-set domain PKD PF00801.20 KFM82209.1 - 0.012 15.4 1.0 0.89 9.4 0.0 3.3 3 0 0 3 3 3 0 PKD domain V-set_CD47 PF08204.11 KFM82209.1 - 0.033 14.2 2.0 0.44 10.5 0.4 2.7 2 1 1 3 3 2 0 CD47 immunoglobulin-like domain C2-set PF05790.15 KFM82209.1 - 0.043 14.0 0.1 2.3 8.4 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Aminotran_5 PF00266.19 KFM82209.1 - 0.086 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V LapA_dom PF06305.11 KFM82209.1 - 1.2 9.0 3.0 0.49 10.2 0.3 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PHD PF00628.29 KFM82210.1 - 3.4e-05 23.6 12.7 5.2e-05 23.0 11.9 1.8 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 KFM82210.1 - 0.0031 17.0 7.7 0.0031 17.0 7.7 2.3 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 KFM82210.1 - 0.045 14.1 2.4 0.12 12.7 2.4 1.7 1 0 0 1 1 1 0 C1 domain Ribosomal_L27A PF00828.19 KFM82211.1 - 3.5e-19 69.7 0.0 5.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MBOAT PF03062.19 KFM82212.1 - 1.3e-12 47.7 15.8 1.3e-12 47.7 15.8 2.1 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family HMG_box PF00505.19 KFM82214.1 - 3.4e-17 62.6 1.0 5.8e-17 61.9 1.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM82214.1 - 1.1e-05 25.9 1.1 1.1e-05 25.9 1.1 1.8 2 0 0 2 2 2 1 HMG-box domain Herpes_LMP1 PF05297.11 KFM82214.1 - 0.64 9.2 5.4 0.86 8.7 5.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) adh_short PF00106.25 KFM82215.1 - 1.3e-42 145.5 0.0 2.1e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM82215.1 - 3.1e-30 105.4 0.0 5.1e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFM82215.1 - 7.4e-10 38.7 0.0 1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KFM82215.1 - 1.7e-08 34.6 0.0 2.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 KR domain PAF-AH_p_II PF03403.13 KFM82215.1 - 0.078 11.5 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Laminin_EGF PF00053.24 KFM82216.1 - 7.9e-76 250.0 224.8 2.9e-11 43.3 14.0 11.8 12 0 0 12 12 12 11 Laminin EGF domain Laminin_B PF00052.18 KFM82216.1 - 3.2e-31 108.0 0.0 6.2e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_II PF06009.12 KFM82216.1 - 1.6 8.8 44.2 0.019 15.0 5.6 6.2 2 1 5 7 7 7 0 Laminin Domain II MCPsignal PF00015.21 KFM82216.1 - 6.2 6.6 30.6 1.1 9.0 3.1 5.2 4 1 2 6 6 6 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_N PF00055.17 KFM82217.1 - 5.3e-57 193.1 0.1 6.4e-57 192.8 0.1 1.1 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) LRR_8 PF13855.6 KFM82218.1 - 4.9e-31 106.3 20.9 1.7e-12 46.9 2.3 3.7 2 1 2 4 4 4 3 Leucine rich repeat 7tm_1 PF00001.21 KFM82218.1 - 1.1e-24 87.1 18.4 1.6e-24 86.7 18.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 KFM82218.1 - 4.2e-13 49.4 0.2 8.7e-13 48.4 0.2 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM82218.1 - 5.3e-11 42.6 18.8 0.00019 21.7 0.3 5.1 2 1 5 7 7 7 6 Leucine Rich repeats (2 copies) Ldl_recept_a PF00057.18 KFM82218.1 - 9.5e-10 38.5 15.4 1.7e-07 31.3 5.5 3.5 4 0 0 4 4 3 2 Low-density lipoprotein receptor domain class A LRR_6 PF13516.6 KFM82218.1 - 0.00022 21.0 5.6 3.7 7.8 0.2 5.2 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 KFM82218.1 - 0.00048 20.3 6.9 5.5 7.9 0.1 6.5 6 0 0 6 6 5 1 Leucine Rich Repeat LRR_9 PF14580.6 KFM82218.1 - 0.0041 16.7 2.1 0.44 10.0 1.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Git3 PF11710.8 KFM82218.1 - 0.18 11.6 16.1 0.41 10.4 16.1 1.6 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Bac_export_2 PF01312.19 KFM82218.1 - 3 7.0 5.3 1.3 8.1 2.0 1.9 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DUF373 PF04123.13 KFM82218.1 - 9.5 5.5 12.2 3.8 6.9 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Ldl_recept_a PF00057.18 KFM82219.1 - 1.2e-33 115.1 51.5 6.6e-10 39.0 9.7 4.7 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFM82219.1 - 1.7e-25 89.4 0.1 4e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 CUB domain Lectin_C PF00059.21 KFM82219.1 - 1.6e-11 44.9 1.3 1.7e-10 41.6 0.5 3.0 2 1 0 2 2 2 1 Lectin C-type domain CUB PF00431.20 KFM82220.1 - 2e-13 50.6 0.1 4e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 CUB domain F5_F8_type_C PF00754.25 KFM82220.1 - 3.7e-13 49.7 0.0 3.2e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain Sad1_UNC PF07738.13 KFM82220.1 - 0.0013 18.8 0.2 0.0055 16.7 0.0 2.2 3 1 0 3 3 3 1 Sad1 / UNC-like C-terminal ApeC PF16977.5 KFM82221.1 - 5.7e-53 179.9 0.3 9.6e-53 179.2 0.3 1.3 1 0 0 1 1 1 1 C-terminal domain of apextrin CUB PF00431.20 KFM82221.1 - 1.8e-09 37.9 1.2 0.00017 21.9 0.0 3.0 3 0 0 3 3 3 2 CUB domain F5_F8_type_C PF00754.25 KFM82221.1 - 0.019 15.1 0.1 0.047 13.8 0.1 1.6 1 0 0 1 1 1 0 F5/8 type C domain 7tm_1 PF00001.21 KFM82222.1 - 6.8e-23 81.3 20.3 8.5e-23 81.0 20.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KFM82222.1 - 0.083 12.7 17.7 0.22 11.3 17.7 1.7 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Serpentine_r_xa PF03383.15 KFM82222.1 - 0.22 11.5 11.5 0.039 13.9 4.6 2.3 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa LRR_8 PF13855.6 KFM82223.1 - 4.1e-26 90.5 28.4 1.7e-12 46.9 6.3 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFM82223.1 - 9e-09 35.5 13.0 3.1e-05 24.2 3.1 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM82223.1 - 7e-06 26.0 0.1 8.4e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM82223.1 - 0.00099 19.3 5.3 1.2 9.9 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich Repeat LRRNT PF01462.18 KFM82223.1 - 0.028 14.1 2.3 0.05 13.3 2.3 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFM82223.1 - 0.56 10.4 7.5 18 5.7 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Ldl_recept_a PF00057.18 KFM82224.1 - 7.7e-07 29.2 0.4 7.7e-07 29.2 0.4 4.2 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 KFM82225.1 - 3e-07 30.5 3.3 3e-07 30.5 3.3 1.6 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A FlaA PF04620.12 KFM82225.1 - 0.2 11.3 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Flagellar filament outer layer protein Flaa Lectin_C PF00059.21 KFM82226.1 - 4.6e-09 37.0 0.1 8.4e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 KFM82226.1 - 0.021 14.5 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like ApeC PF16977.5 KFM82229.1 - 7.9e-41 140.3 3.9 9.2e-41 140.0 3.9 1.1 1 0 0 1 1 1 1 C-terminal domain of apextrin PROL5-SMR PF15621.6 KFM82232.1 - 0.022 15.3 0.3 0.023 15.2 0.3 1.3 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Amino_oxidase PF01593.24 KFM82234.1 - 1.6e-22 80.4 0.0 1.9e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM82234.1 - 1.3e-12 47.8 0.1 2e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM82234.1 - 3.5e-07 30.1 0.0 3.4e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFM82234.1 - 0.00067 19.0 0.0 0.00098 18.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KFM82234.1 - 0.0047 15.7 0.0 0.21 10.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KFM82234.1 - 0.0047 17.5 0.0 0.023 15.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM82234.1 - 0.0079 15.5 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KFM82234.1 - 0.025 13.4 0.1 0.04 12.7 0.1 1.2 1 0 0 1 1 1 0 MCRA family FAD_binding_2 PF00890.24 KFM82234.1 - 0.034 13.2 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KFM82235.1 - 0.00019 20.8 0.0 0.00019 20.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase RT_RNaseH_2 PF17919.1 KFM82237.1 - 8.1e-31 106.0 0.0 1.8e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFM82237.1 - 1.8e-27 95.7 0.0 4.3e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFM82237.1 - 2.3e-18 66.5 0.2 9.1e-18 64.6 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KFM82237.1 - 9.6e-15 54.4 0.6 2.9e-14 52.9 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KFM82237.1 - 8.4e-07 29.2 0.0 2.9e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 KFM82237.1 - 0.00043 20.2 0.5 0.00043 20.2 0.5 2.0 2 0 0 2 2 2 1 Zinc knuckle DUF3878 PF12994.7 KFM82237.1 - 0.0079 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3878) DUF5526 PF17664.1 KFM82237.1 - 0.071 12.7 1.2 2.9 7.4 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5526) Tmemb_55A PF09788.9 KFM82238.1 - 3.4e-23 82.0 12.4 3.7e-23 81.9 12.4 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A IBR PF01485.21 KFM82238.1 - 0.038 14.2 9.3 3.8 7.8 4.2 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Mnd1 PF03962.15 KFM82239.1 - 0.0015 18.8 0.1 0.0025 18.1 0.1 1.3 1 0 0 1 1 1 1 Mnd1 HTH domain Calpain_u2 PF16648.5 KFM82239.1 - 0.078 13.4 1.4 0.12 12.9 0.6 1.7 1 1 1 2 2 2 0 Unstructured region on Calpain-3 TraB PF01963.17 KFM82240.1 - 8.4e-15 55.4 0.0 8.8e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 TraB family LisH PF08513.11 KFM82240.1 - 0.045 13.7 0.6 0.098 12.7 0.1 1.8 2 0 0 2 2 2 0 LisH Nexin_C PF08628.12 KFM82241.1 - 1.1e-24 87.1 0.4 1.7e-24 86.6 0.4 1.3 1 0 0 1 1 1 1 Sorting nexin C terminal TLC PF03219.14 KFM82241.1 - 0.095 11.4 0.6 2.5 6.7 0.0 2.0 2 0 0 2 2 2 0 TLC ATP/ADP transporter FeoB_Cyto PF17910.1 KFM82241.1 - 0.11 13.0 0.1 0.38 11.3 0.0 1.8 2 0 0 2 2 2 0 FeoB cytosolic helical domain RGS PF00615.19 KFM82242.1 - 3.2e-20 72.6 1.0 3.2e-20 72.6 1.0 3.1 3 1 0 3 3 3 1 Regulator of G protein signaling domain PXA PF02194.15 KFM82242.1 - 1.2e-17 64.5 3.7 1.8e-17 63.9 0.9 2.6 2 1 0 2 2 2 1 PXA domain PX PF00787.24 KFM82242.1 - 5.9e-08 32.7 0.6 2.4e-07 30.7 0.1 2.4 2 0 0 2 2 2 1 PX domain Isy1 PF06246.12 KFM82242.1 - 0.00035 20.2 0.1 0.00035 20.2 0.1 3.1 2 2 0 2 2 2 1 Isy1-like splicing family Cauli_AT PF03233.13 KFM82242.1 - 0.1 12.6 0.1 0.1 12.6 0.1 3.1 2 1 1 3 3 3 0 Aphid transmission protein GerA PF03323.13 KFM82242.1 - 0.16 10.4 1.1 0.22 9.9 0.2 1.6 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein RanGAP1_C PF07834.11 KFM82243.1 - 6.5e-31 107.3 0.4 1.1e-30 106.6 0.4 1.3 1 0 0 1 1 1 1 RanGAP1 C-terminal domain LRR_6 PF13516.6 KFM82243.1 - 1.3e-19 68.5 12.4 0.028 14.5 0.0 9.0 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 KFM82243.1 - 2.1e-07 31.1 14.3 0.071 13.6 0.1 6.6 5 1 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM82243.1 - 1.1e-06 28.3 8.3 0.037 13.8 0.7 5.8 5 2 0 5 5 5 2 Leucine rich repeat SDA1 PF05285.12 KFM82243.1 - 0.075 12.5 5.5 0.11 11.9 5.5 1.2 1 0 0 1 1 1 0 SDA1 TLP-20 PF06088.11 KFM82243.1 - 0.081 12.8 2.4 0.14 12.0 2.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) LRR_1 PF00560.33 KFM82243.1 - 0.12 13.0 12.6 46 5.1 0.1 7.1 7 0 0 7 7 6 0 Leucine Rich Repeat Nop14 PF04147.12 KFM82243.1 - 0.57 8.3 10.4 0.85 7.8 10.4 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KFM82243.1 - 0.86 8.9 7.1 1.3 8.3 7.1 1.2 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 KFM82243.1 - 1.4 8.1 4.2 2.2 7.4 4.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 KFM82243.1 - 4.9 5.3 9.8 6.9 4.8 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KFM82243.1 - 5.1 5.5 7.2 7.8 4.9 7.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 KFM82243.1 - 9.7 5.5 11.2 18 4.6 11.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CAP-ZIP_m PF15255.6 KFM82244.1 - 7.1e-07 29.6 1.8 1.2e-06 28.8 1.1 1.8 1 1 0 1 1 1 1 WASH complex subunit CAP-Z interacting, central region Ndc1_Nup PF09531.10 KFM82244.1 - 0.41 9.3 7.2 0.69 8.5 7.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CUB PF00431.20 KFM82245.1 - 7.2e-19 68.2 1.2 2.9e-06 27.6 0.0 3.9 4 0 0 4 4 4 3 CUB domain Trm112p PF03966.16 KFM82246.1 - 2.1e-13 50.6 0.0 3.3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Trm112p-like protein LCM PF04072.14 KFM82247.1 - 1.2e-26 93.8 0.0 2.5e-26 92.8 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase MAP65_ASE1 PF03999.12 KFM82249.1 - 1.4e-94 317.9 43.0 2e-94 317.4 43.0 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Mnd1 PF03962.15 KFM82249.1 - 0.029 14.6 0.9 0.64 10.4 0.4 2.9 2 0 0 2 2 2 0 Mnd1 HTH domain HisKA_2 PF07568.12 KFM82249.1 - 0.28 11.3 3.4 0.48 10.5 0.2 3.0 2 1 0 2 2 2 0 Histidine kinase cwf21 PF08312.12 KFM82249.1 - 8.7 6.6 8.9 26 5.1 0.5 4.3 2 1 0 2 2 2 0 cwf21 domain GST_C_2 PF13410.6 KFM82250.1 - 0.00017 21.5 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Dymeclin PF09742.9 KFM82251.1 - 2.1e-148 495.5 27.2 2.4e-148 495.4 27.2 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KFM82251.1 - 5.9e-09 34.7 19.8 7.3e-06 24.4 5.6 3.1 2 1 1 3 3 3 2 High-temperature-induced dauer-formation protein DUF735 PF05246.11 KFM82251.1 - 0.072 13.0 3.0 0.19 11.7 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF735) Ndr PF03096.14 KFM82253.1 - 2.1e-75 253.1 0.2 2.4e-75 252.8 0.2 1.0 1 0 0 1 1 1 1 Ndr family UQ_con PF00179.26 KFM82254.1 - 1.7e-18 66.7 0.0 5.9e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM82254.1 - 0.033 14.5 0.1 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 RWD domain PH PF00169.29 KFM82255.1 - 0.00045 20.7 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 PH domain CytochromB561_N PF09786.9 KFM82255.1 - 2.5 7.0 9.8 1.4 7.8 0.5 2.1 1 1 1 2 2 2 0 Cytochrome B561, N terminal Bax1-I PF01027.20 KFM82257.1 - 4.1e-08 33.3 2.2 4.4e-08 33.2 2.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spo7 PF03907.13 KFM82257.1 - 0.11 12.0 0.4 0.12 11.9 0.4 1.0 1 0 0 1 1 1 0 Spo7-like protein Hum_adeno_E3A PF05393.11 KFM82257.1 - 8.6 6.4 7.2 13 5.9 3.3 2.0 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein Bax1-I PF01027.20 KFM82259.1 - 0.0048 16.8 4.8 0.0048 16.7 4.8 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 VEGFR-2_TMD PF17988.1 KFM82259.1 - 4.5 6.8 8.3 0.35 10.3 3.3 1.7 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain Bax1-I PF01027.20 KFM82260.1 - 7.9e-08 32.4 0.2 8.2e-08 32.3 0.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 LRR_4 PF12799.7 KFM82262.1 - 8.3e-05 22.9 0.3 0.37 11.3 0.0 3.9 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM82262.1 - 0.00023 21.3 0.9 0.46 11.2 0.6 4.1 4 0 0 4 4 4 1 Leucine Rich Repeat CEP209_CC5 PF16574.5 KFM82262.1 - 0.087 13.0 0.1 0.19 11.9 0.1 1.6 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 LRR_6 PF13516.6 KFM82262.1 - 0.26 11.4 1.4 40 4.6 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.7 KFM82263.1 - 7.7e-11 41.7 0.7 1.7e-10 40.6 0.7 1.6 1 0 0 1 1 1 1 F-box-like XPA_N PF01286.18 KFM82263.1 - 0.002 18.1 0.6 0.0033 17.4 0.0 1.7 2 0 0 2 2 2 1 XPA protein N-terminal Mor PF08765.11 KFM82263.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Mor transcription activator family F-box PF00646.33 KFM82263.1 - 0.97 9.4 4.3 4.3 7.3 2.3 2.8 3 1 0 3 3 3 0 F-box domain Zip PF02535.22 KFM82264.1 - 1.8e-68 231.3 7.8 3.1e-68 230.5 7.8 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Adeno_E3B PF03376.14 KFM82264.1 - 0.048 13.9 1.5 4.3 7.6 0.6 2.7 2 0 0 2 2 2 0 Adenovirus E3B protein Urb2 PF10441.9 KFM82264.1 - 0.049 13.6 1.1 0.099 12.6 1.1 1.5 1 0 0 1 1 1 0 Urb2/Npa2 family DUF2721 PF11026.8 KFM82264.1 - 2.7 7.9 11.2 12 5.7 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MULE PF10551.9 KFM82265.1 - 2.1e-10 40.8 0.0 3.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF4780 PF16012.5 KFM82265.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) PhnA_Zn_Ribbon PF08274.12 KFM82266.1 - 0.00095 19.1 0.2 0.36 10.8 0.2 2.3 2 0 0 2 2 2 2 PhnA Zinc-Ribbon DNA_ligase_ZBD PF03119.16 KFM82266.1 - 0.0013 18.7 0.2 0.0013 18.7 0.2 2.1 2 1 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain zf-TFIIB PF13453.6 KFM82266.1 - 0.0019 17.5 0.3 0.006 15.9 0.1 1.9 2 0 0 2 2 2 1 Transcription factor zinc-finger Ogr_Delta PF04606.12 KFM82266.1 - 0.024 14.6 3.7 0.045 13.7 3.7 1.5 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.6 KFM82266.1 - 0.078 13.5 6.9 0.11 13.1 6.9 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Zona_pellucida PF00100.23 KFM82268.1 - 0.00024 21.0 0.0 0.00057 19.8 0.0 1.6 2 0 0 2 2 2 1 Zona pellucida-like domain PRIMA1 PF16101.5 KFM82268.1 - 0.01 15.9 2.4 0.032 14.2 2.4 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 BRF1 PF07741.13 KFM82269.1 - 1.3e-22 80.1 7.6 1.3e-22 80.1 7.6 2.8 3 1 0 3 3 3 1 Brf1-like TBP-binding domain DUF3573 PF12097.8 KFM82269.1 - 0.073 11.9 1.2 0.14 10.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TFIIB PF00382.19 KFM82270.1 - 1.7e-23 82.4 0.3 4.1e-16 58.8 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KFM82270.1 - 5.7e-12 45.0 0.6 1.1e-11 44.0 0.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KFM82270.1 - 0.0041 17.1 0.4 0.0061 16.6 0.4 1.2 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain 2Fe-2S_thioredx PF01257.19 KFM82270.1 - 0.012 15.4 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin OrfB_Zn_ribbon PF07282.11 KFM82270.1 - 0.016 15.1 2.4 0.042 13.8 0.9 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 KFM82270.1 - 0.044 13.8 0.6 0.16 12.0 0.3 2.0 2 0 0 2 2 2 0 Double zinc ribbon YhfH PF14149.6 KFM82270.1 - 0.42 10.6 3.6 2.9 7.9 0.2 2.5 2 0 0 2 2 2 0 YhfH-like protein zf-ribbon_3 PF13248.6 KFM82270.1 - 0.54 9.7 3.4 4.3 6.9 3.4 2.2 1 1 0 1 1 1 0 zinc-ribbon domain FlaC_arch PF05377.11 KFM82271.1 - 0.017 15.5 0.1 0.053 13.9 0.1 1.9 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KFM82271.1 - 0.017 14.8 1.6 0.017 14.8 1.6 2.3 2 1 0 2 2 2 0 Septum formation initiator HTH_40 PF14493.6 KFM82271.1 - 0.029 14.8 1.8 0.1 13.1 0.2 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_GP20 PF06810.11 KFM82271.1 - 0.22 11.3 12.1 1.3 8.8 1.1 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 CCDC-167 PF15188.6 KFM82271.1 - 0.34 11.3 4.9 0.5 10.7 4.9 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 IFP_35_N PF07334.13 KFM82271.1 - 2.4 8.3 6.7 5.7 7.1 0.9 2.4 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FYVE_2 PF02318.16 KFM82273.1 - 8.1e-35 119.6 4.2 1.3e-34 118.9 4.2 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 KFM82273.1 - 0.00031 20.8 7.6 0.0007 19.7 7.6 1.6 1 0 0 1 1 1 1 Piccolo Zn-finger FYVE PF01363.21 KFM82273.1 - 0.0084 16.2 4.4 0.019 15.1 4.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF512 PF04459.12 KFM82273.1 - 0.037 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) MRP-S34 PF16053.5 KFM82273.1 - 0.039 13.6 1.7 0.053 13.2 0.4 1.9 2 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S34 Zn_Tnp_IS91 PF14319.6 KFM82273.1 - 0.057 13.5 0.9 0.15 12.1 0.9 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain GA PF01468.17 KFM82273.1 - 0.075 13.3 0.9 0.15 12.4 0.9 1.4 1 0 0 1 1 1 0 GA module PHD PF00628.29 KFM82273.1 - 0.34 10.8 10.6 0.24 11.3 8.0 2.0 2 0 0 2 2 2 0 PHD-finger zf-Sec23_Sec24 PF04810.15 KFM82273.1 - 9.4 6.4 7.8 1.6 8.9 2.0 2.5 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Ribosomal_L7Ae PF01248.26 KFM82275.1 - 1.4e-26 92.0 0.0 1.7e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 KFM82275.1 - 0.008 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase eRF1_3 PF03465.15 KFM82275.1 - 0.14 12.6 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 eRF1 domain 3 La PF05383.17 KFM82277.1 - 1.3e-18 66.8 0.3 2.2e-18 66.1 0.3 1.4 1 0 0 1 1 1 1 La domain PTS_2-RNA PF01885.16 KFM82277.1 - 0.074 13.1 0.1 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Methyltransf_16 PF10294.9 KFM82279.1 - 4.3e-10 39.6 0.1 7e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFM82279.1 - 1.5e-07 31.4 0.0 2.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM82279.1 - 2.6e-06 27.3 0.1 6.3e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM82279.1 - 0.00024 21.7 0.0 0.0011 19.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 KFM82279.1 - 0.00032 20.1 0.0 0.00076 18.8 0.0 1.6 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.12 KFM82279.1 - 0.009 16.6 0.1 0.039 14.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFM82279.1 - 0.036 13.5 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) EF-hand_7 PF13499.6 KFM82280.1 - 9.8e-26 90.0 7.2 1.4e-13 51.1 2.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM82280.1 - 1.9e-24 83.3 15.0 1.6e-08 33.5 0.8 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFM82280.1 - 2.4e-18 64.4 10.6 0.00012 21.7 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFM82280.1 - 3.2e-18 65.3 11.2 2.9e-12 46.3 0.6 3.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KFM82280.1 - 4.6e-14 52.5 0.1 1.5e-06 28.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFM82280.1 - 0.0002 20.7 15.0 0.0022 17.4 1.1 4.0 4 1 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 KFM82280.1 - 0.00033 20.6 2.6 0.0043 17.0 0.6 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KFM82280.1 - 0.0042 17.4 1.5 0.7 10.3 0.2 2.5 1 1 1 2 2 2 1 EF-hand domain Leucyl-specific PF14795.6 KFM82280.1 - 0.0059 16.7 0.8 0.55 10.4 0.2 2.4 2 0 0 2 2 2 1 Leucine-tRNA synthetase-specific domain LETM1 PF07766.13 KFM82280.1 - 0.12 11.6 2.5 0.15 11.4 1.1 1.7 1 1 1 2 2 2 0 LETM1-like protein RuvA_C PF07499.13 KFM82280.1 - 0.14 12.7 0.0 0.58 10.7 0.0 2.0 2 0 0 2 2 2 0 RuvA, C-terminal domain SUB1_ProdP9 PF18213.1 KFM82280.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.4 2 1 0 3 3 3 0 SUB1 protease Prodomain ProdP9 GP17 PF17420.2 KFM82280.1 - 0.17 12.1 1.1 0.26 11.4 0.4 1.7 2 0 0 2 2 2 0 Superinfection exclusion gene product 17 Phage_TAC_12 PF12363.8 KFM82280.1 - 0.44 11.0 5.5 2.9 8.3 0.4 2.5 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC Aldedh PF00171.22 KFM82283.1 - 1.9e-109 366.2 0.1 2.3e-109 366.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3903 PF13043.6 KFM82283.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) Lsm_C PF14894.6 KFM82284.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Lsm C-terminal p450 PF00067.22 KFM82285.1 - 4.9e-74 249.7 0.0 6.1e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Solute_trans_a PF03619.16 KFM82286.1 - 2.7e-93 312.4 16.1 3.2e-93 312.1 16.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Ras PF00071.22 KFM82287.1 - 2e-37 128.3 0.0 2.4e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM82287.1 - 8.6e-16 58.2 0.0 1.3e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM82287.1 - 4.2e-11 42.6 0.0 5.2e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM82287.1 - 1e-06 28.4 0.1 5.5e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM82287.1 - 2.3e-05 24.3 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFM82287.1 - 2.7e-05 23.7 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFM82287.1 - 4.7e-05 22.8 0.0 5.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KFM82287.1 - 0.00037 20.9 0.0 0.00091 19.6 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain TniB PF05621.11 KFM82287.1 - 0.0014 18.0 0.0 0.0048 16.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 KFM82287.1 - 0.0017 18.6 0.0 0.0056 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFM82287.1 - 0.002 18.2 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase OKR_DC_1_N PF03709.15 KFM82287.1 - 0.005 17.1 0.0 0.0099 16.1 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_28 PF13521.6 KFM82287.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFM82287.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF211 PF02680.14 KFM82287.1 - 0.026 14.7 0.2 1.8 8.8 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 ATP_bind_1 PF03029.17 KFM82287.1 - 0.048 13.4 0.0 9.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KFM82287.1 - 0.051 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KFM82287.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFM82287.1 - 0.065 13.3 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 KFM82287.1 - 0.095 11.8 0.0 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA PF00004.29 KFM82287.1 - 0.13 12.6 0.0 0.89 10.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFM82287.1 - 0.13 11.9 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain IQ_SEC7_PH PF16453.5 KFM82287.1 - 0.13 12.2 0.0 0.57 10.2 0.0 1.9 2 0 0 2 2 2 0 PH domain zf-RING_UBOX PF13445.6 KFM82288.1 - 4.7e-08 32.9 6.0 4.7e-08 32.9 6.0 2.4 2 0 0 2 2 1 1 RING-type zinc-finger NHL PF01436.21 KFM82288.1 - 7.2e-08 32.1 0.1 1.7e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 NHL repeat zf-C3HC4 PF00097.25 KFM82288.1 - 2e-07 30.7 7.8 2e-07 30.7 7.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM82288.1 - 1.5e-06 27.9 7.8 1.5e-06 27.9 7.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM82288.1 - 3.1e-05 23.7 8.6 3.1e-05 23.7 8.6 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM82288.1 - 3.7e-05 24.0 7.9 3.7e-05 24.0 7.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFM82288.1 - 0.00015 21.6 6.7 0.00015 21.6 6.7 2.8 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM82288.1 - 0.00091 19.3 8.5 0.00091 19.3 8.5 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFM82288.1 - 0.92 9.4 22.8 0.021 14.7 6.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-B_box PF00643.24 KFM82288.1 - 1.1 9.4 13.6 0.024 14.8 4.8 2.7 3 0 0 3 3 3 0 B-box zinc finger DUF2120 PF09893.9 KFM82288.1 - 3.6 7.7 7.9 75 3.4 7.9 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Inositol_P PF00459.25 KFM82289.1 - 1.4e-47 162.5 0.0 1.7e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.25 KFM82290.1 - 3.5e-11 43.0 0.0 5e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SNAP-25 PF00835.19 KFM82290.1 - 0.0068 16.7 0.2 0.02 15.2 0.2 1.8 1 0 0 1 1 1 1 SNAP-25 family Pkinase PF00069.25 KFM82291.1 - 3.8e-38 131.3 0.4 4.3e-38 131.2 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM82291.1 - 3.6e-22 78.9 0.2 4.3e-22 78.6 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Anoct_dimer PF16178.5 KFM82291.1 - 0.0021 17.8 0.2 0.0026 17.5 0.2 1.1 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Kdo PF06293.14 KFM82291.1 - 0.039 13.3 0.1 0.2 11.0 0.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFM82291.1 - 0.047 13.3 0.1 0.059 13.0 0.1 1.3 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PIEZO PF15917.5 KFM82292.1 - 1.1e-43 149.3 14.5 4.9e-43 147.2 3.8 2.7 2 1 1 3 3 3 2 Piezo Piezo_RRas_bdg PF12166.8 KFM82293.1 - 1.1e-52 179.8 0.0 1.3e-52 179.6 0.0 1.0 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain DUF866 PF05907.13 KFM82294.1 - 0.029 14.3 0.1 0.036 14.0 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-LITAF-like PF10601.9 KFM82294.1 - 0.073 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF4668 PF15701.5 KFM82294.1 - 0.32 10.8 1.4 0.44 10.4 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Transglut_C PF00927.22 KFM82295.1 - 1.1e-29 102.7 0.0 1.1e-15 57.6 0.1 2.3 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 KFM82295.1 - 8.8e-25 87.4 0.0 4.8e-23 81.7 0.0 3.0 3 0 0 3 3 3 1 Transglutaminase family Transglut_core PF01841.19 KFM82295.1 - 7.8e-16 58.5 0.1 1.7e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily RNA_pol_Rpb2_2 PF04561.14 KFM82297.1 - 0.035 13.7 0.0 0.035 13.7 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 EGF PF00008.27 KFM82298.1 - 2e-05 24.8 7.1 3.6e-05 24.0 7.1 1.4 1 0 0 1 1 1 1 EGF-like domain Insulin_TMD PF17870.1 KFM82298.1 - 0.00013 21.9 2.5 0.00029 20.8 2.5 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF3377 PF11857.8 KFM82298.1 - 0.0096 15.8 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) hEGF PF12661.7 KFM82298.1 - 0.0098 16.5 4.3 0.027 15.1 4.3 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF GAPT PF11770.8 KFM82298.1 - 0.044 13.6 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) SKG6 PF08693.10 KFM82298.1 - 0.21 11.0 8.4 0.42 10.1 8.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF_2 PF07974.13 KFM82298.1 - 0.22 12.0 9.3 0.4 11.1 9.3 1.4 1 0 0 1 1 1 0 EGF-like domain Chi-conotoxin PF16981.5 KFM82298.1 - 1.1 9.5 3.6 2.9 8.2 3.6 1.7 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily Ldl_recept_a PF00057.18 KFM82299.1 - 4.6e-196 634.7 404.8 2.5e-11 43.6 17.6 23.1 22 1 1 23 23 23 21 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFM82299.1 - 4.6e-112 366.3 29.0 1.3e-09 38.4 0.2 22.3 22 1 0 22 22 22 19 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.5 KFM82299.1 - 1.1e-31 110.1 6.3 6.5e-09 35.4 0.6 6.6 5 3 0 5 5 5 4 Domain of unknown function (DUF5050) FXa_inhibition PF14670.6 KFM82299.1 - 6.4e-21 74.4 187.8 1.2e-07 31.8 4.6 14.8 12 2 2 14 14 14 8 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFM82299.1 - 1.7e-14 53.7 44.3 1.4e-08 34.8 9.1 22.8 15 7 8 23 23 23 3 Calcium-binding EGF domain SGL PF08450.12 KFM82299.1 - 1.9e-11 44.0 10.0 0.00015 21.4 0.0 8.4 6 3 1 8 8 8 2 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 KFM82299.1 - 4.1e-11 42.6 9.0 1.5e-08 34.4 1.5 11.3 11 0 0 11 11 11 3 Complement Clr-like EGF-like Arylesterase PF01731.20 KFM82299.1 - 6e-06 26.4 0.1 1.9 8.8 0.0 5.4 3 2 2 5 5 5 2 Arylesterase OTU PF02338.19 KFM82301.1 - 0.013 16.0 0.1 0.022 15.2 0.1 1.4 1 0 0 1 1 1 0 OTU-like cysteine protease MCM_OB PF17207.3 KFM82301.1 - 0.29 11.0 2.6 0.54 10.1 2.6 1.4 1 0 0 1 1 1 0 MCM OB domain Ank_4 PF13637.6 KFM82303.1 - 0.0017 18.9 0.0 0.0022 18.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM82303.1 - 0.011 16.1 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 KFM82303.1 - 0.025 15.0 0.0 4.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 KFM82303.1 - 0.065 13.8 0.0 0.076 13.6 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM82303.1 - 0.16 12.6 0.0 22 6.0 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Trypsin PF00089.26 KFM82304.1 - 1e-12 48.4 0.0 1e-12 48.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM82304.1 - 0.11 12.9 0.2 0.13 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) OATP PF03137.20 KFM82306.1 - 0.059 11.7 0.1 0.063 11.6 0.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2830 PF11125.8 KFM82306.1 - 0.096 12.7 0.0 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) OATP PF03137.20 KFM82307.1 - 2.4e-95 319.9 2.2 2.8e-95 319.7 2.2 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFM82307.1 - 1.4e-11 43.9 8.6 1.5e-11 43.8 2.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFM82307.1 - 1.5e-09 37.8 9.7 3.3e-09 36.7 9.7 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM82307.1 - 0.00013 21.9 7.2 0.00057 19.8 7.1 2.1 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Baculo_11_kDa PF06143.11 KFM82307.1 - 0.11 12.1 1.2 9.4 5.9 1.7 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family RhoGEF PF00621.20 KFM82310.1 - 4.6e-21 75.9 0.2 5.9e-21 75.5 0.2 1.1 1 0 0 1 1 1 1 RhoGEF domain DUF3246 PF11596.8 KFM82310.1 - 0.012 15.1 1.7 0.052 13.0 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) SR-25 PF10500.9 KFM82310.1 - 0.31 10.6 7.6 0.63 9.6 7.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RhoGEF PF00621.20 KFM82311.1 - 4.8e-14 53.0 0.4 9.7e-14 52.0 0.1 1.6 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFM82311.1 - 1.7e-06 28.5 0.4 4.4e-05 23.9 0.1 2.2 1 1 1 2 2 2 1 PH domain PH_10 PF15411.6 KFM82311.1 - 0.015 15.6 3.8 0.028 14.7 1.3 2.7 2 1 1 3 3 3 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFM82311.1 - 0.021 14.8 0.9 0.062 13.3 0.3 2.1 2 1 0 2 2 2 0 PH domain zf-SAP30 PF13866.6 KFM82313.1 - 1.1e-39 134.4 5.5 2.1e-39 133.5 5.5 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger SAP30_Sin3_bdg PF13867.6 KFM82313.1 - 3.4e-23 81.7 0.8 5.5e-23 81.1 0.8 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Ac110_PIF PF07280.11 KFM82313.1 - 0.0055 16.4 0.0 0.38 10.6 0.0 2.4 2 0 0 2 2 2 1 Per os infectivity factor AC110 baeRF_family8 PF18851.1 KFM82314.1 - 0.034 14.2 0.7 0.036 14.1 0.7 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 End3 PF12761.7 KFM82315.1 - 0.0097 16.1 1.8 0.011 15.9 1.8 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 DIRP PF06584.13 KFM82315.1 - 0.02 15.1 0.2 0.022 14.9 0.2 1.1 1 0 0 1 1 1 0 DIRP HTH_11 PF08279.12 KFM82315.1 - 0.058 13.4 1.0 0.36 10.8 0.3 2.5 2 2 1 3 3 3 0 HTH domain DUF4256 PF14066.6 KFM82315.1 - 0.096 12.4 1.3 0.11 12.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) DUF1444 PF07285.11 KFM82316.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) Pkinase_Tyr PF07714.17 KFM82319.1 - 3.3e-17 62.6 0.0 4.3e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM82319.1 - 1.9e-09 37.3 0.0 2.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF2627 PF11118.8 KFM82319.1 - 0.03 14.9 0.0 0.05 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Peptidase_M1 PF01433.20 KFM82320.1 - 1.3e-82 276.6 2.1 2.9e-82 275.5 2.1 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFM82320.1 - 1.3e-81 274.6 0.5 2e-81 274.0 0.5 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Neural_ProG_Cyt PF06567.11 KFM82320.1 - 0.12 12.6 0.0 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Peptidase_M1_N PF17900.1 KFM82321.1 - 2.1e-15 57.4 0.1 2.3e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 KFM82322.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 ERAP1-like C-terminal domain ERAP1_C PF11838.8 KFM82323.1 - 0.01 15.4 0.1 0.011 15.3 0.1 1.0 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFM82324.1 - 1.6e-07 31.7 0.2 1.7e-07 31.6 0.2 1.0 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain RNA_bind PF08675.11 KFM82324.1 - 0.094 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain ERAP1_C PF11838.8 KFM82326.1 - 3.4e-09 36.7 0.2 3.5e-09 36.6 0.2 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain ERAP1_C PF11838.8 KFM82327.1 - 2.9e-21 76.3 0.0 3.1e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain MAM1 PF10434.9 KFM82327.1 - 0.17 11.5 0.0 0.19 11.3 0.0 1.0 1 0 0 1 1 1 0 Monopolin complex protein MAM1 ERAP1_C PF11838.8 KFM82328.1 - 2.1e-14 53.8 0.3 2.2e-14 53.8 0.3 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFM82331.1 - 2e-07 30.8 0.0 2.1e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFM82332.1 - 4e-49 167.3 2.5 6.4e-49 166.7 2.5 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 KFM82334.1 - 1.3e-30 107.1 0.4 7.2e-16 58.6 0.1 2.1 1 1 1 2 2 2 2 ERAP1-like C-terminal domain Alginate_lyase PF05426.12 KFM82334.1 - 0.0057 16.2 1.1 0.18 11.3 0.1 2.1 2 0 0 2 2 2 2 Alginate lyase Peptidase_M1 PF01433.20 KFM82335.1 - 7.7e-63 212.0 2.3 7.7e-63 212.0 2.3 1.4 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFM82335.1 - 3.3e-12 46.6 0.9 7e-12 45.5 0.9 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF1570 PF07607.11 KFM82335.1 - 0.11 12.9 0.6 0.96 9.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1570) DUF1360 PF07098.11 KFM82335.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Peptidase_M1_N PF17900.1 KFM82336.1 - 2.2e-17 63.9 0.9 5.6e-17 62.5 0.7 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Aconitase PF00330.20 KFM82338.1 - 1.4e-173 578.1 0.0 7.1e-159 529.7 0.0 2.1 2 0 0 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFM82338.1 - 1.4e-44 151.6 0.0 6.2e-44 149.5 0.0 2.0 2 0 0 2 2 2 1 Aconitase C-terminal domain Methyltransf_23 PF13489.6 KFM82339.1 - 2.6e-16 59.9 0.0 3.5e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM82339.1 - 2.9e-16 59.9 0.0 1.1e-15 58.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM82339.1 - 9.4e-14 51.9 0.0 3.2e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM82339.1 - 4.6e-13 49.2 0.0 1.1e-12 48.0 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM82339.1 - 1.5e-11 44.9 0.0 1.3e-10 41.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KFM82339.1 - 1.8e-07 30.7 0.2 2.2e-07 30.5 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KFM82339.1 - 1.9e-06 27.4 0.0 4e-05 23.1 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family DUF3841 PF12952.7 KFM82339.1 - 0.0031 17.3 0.1 0.0084 15.9 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3841) CheR PF01739.18 KFM82339.1 - 0.0032 17.0 0.0 0.016 14.7 0.0 1.9 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain TPMT PF05724.11 KFM82339.1 - 0.0039 16.9 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PI3K_P85_iSH2 PF16454.5 KFM82339.1 - 0.0087 15.7 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain NodS PF05401.11 KFM82339.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Rsbr_N PF08678.10 KFM82339.1 - 0.039 14.0 0.1 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Rsbr N terminal Pyrophosphatase PF00719.19 KFM82341.1 - 0.031 14.1 0.1 0.031 14.1 0.1 1.0 1 0 0 1 1 1 0 Inorganic pyrophosphatase S10_plectin PF03501.15 KFM82342.1 - 4.3e-47 158.1 0.2 5.2e-47 157.8 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Replic_Relax PF13814.6 KFM82342.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation TrmB PF01978.19 KFM82342.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 KFM82342.1 - 0.15 12.0 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit TPR_1 PF00515.28 KFM82343.1 - 3.9e-48 159.4 5.0 2.3e-09 36.7 0.4 10.8 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFM82343.1 - 2e-38 127.4 10.3 6.5e-07 29.0 0.3 10.9 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFM82343.1 - 1.2e-33 112.4 7.5 0.00071 19.6 0.2 10.8 11 0 0 11 11 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM82343.1 - 1e-30 105.7 18.7 2e-21 76.0 2.4 5.1 4 1 1 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KFM82343.1 - 3e-28 97.2 0.0 2.4e-05 23.9 0.0 7.8 3 1 4 7 7 7 6 TPR repeat TPR_12 PF13424.6 KFM82343.1 - 2.3e-25 88.7 5.9 0.0001 22.5 0.0 7.9 6 2 4 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFM82343.1 - 4.3e-22 78.5 0.0 3.4e-07 30.8 0.0 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM82343.1 - 1.2e-18 67.4 3.8 0.031 14.8 0.0 7.6 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFM82343.1 - 1.4e-17 62.9 0.7 0.43 11.5 0.0 8.7 4 1 4 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFM82343.1 - 4.1e-16 58.1 2.4 0.027 14.8 0.0 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFM82343.1 - 1.4e-13 50.5 5.4 0.97 10.2 0.0 9.2 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM82343.1 - 2.9e-12 45.7 5.5 0.02 14.9 0.2 8.7 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM82343.1 - 7.5e-09 35.6 0.2 0.0044 17.1 0.0 4.3 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM82343.1 - 6.8e-07 29.0 2.4 0.46 10.4 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM82343.1 - 0.00063 19.0 0.1 15 4.6 0.2 4.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM82343.1 - 0.0013 18.2 6.1 0.027 13.8 0.3 3.1 3 1 0 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 KFM82343.1 - 0.0018 18.5 0.2 0.1 12.9 0.0 3.5 3 1 2 5 5 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFM82343.1 - 0.022 14.8 7.5 0.28 11.2 0.1 3.6 4 1 0 4 4 3 0 Putative TPR-like repeat TPR_21 PF09976.9 KFM82343.1 - 0.043 13.5 0.4 21 4.7 0.2 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain PPTA PF01239.22 KFM82343.1 - 0.077 12.8 2.0 0.98 9.2 0.2 2.9 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat MAS20 PF02064.15 KFM82343.1 - 0.85 9.7 3.6 4 7.5 0.0 3.0 3 0 0 3 3 3 0 MAS20 protein import receptor Fis1_TPR_C PF14853.6 KFM82343.1 - 1.3 9.1 6.3 71 3.6 0.1 4.4 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KFM82343.1 - 8.8 6.8 8.7 23 5.4 0.5 3.8 4 0 0 4 4 4 0 Bacterial transcriptional activator domain zf-C2H2_7 PF15269.6 KFM82344.1 - 0.0025 17.8 0.5 0.0031 17.6 0.5 1.2 1 0 0 1 1 1 1 Zinc-finger zf-C2H2_2 PF12756.7 KFM82344.1 - 0.0081 16.5 0.6 0.0081 16.5 0.6 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM82344.1 - 0.0093 15.7 0.7 0.013 15.2 0.7 1.3 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM82344.1 - 0.071 14.0 3.0 0.071 14.0 3.0 1.9 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM82344.1 - 0.13 12.8 3.1 0.13 12.8 3.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4358 PF14270.6 KFM82344.1 - 0.15 12.3 0.0 0.19 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) GRP PF07172.11 KFM82347.1 - 0.0003 21.4 10.2 0.0003 21.4 10.2 2.0 1 1 2 3 3 3 1 Glycine rich protein family Lactamase_B PF00753.27 KFM82348.1 - 7.2e-20 71.8 0.6 1.1e-19 71.3 0.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KFM82348.1 - 3.2e-12 46.2 0.3 7.4e-12 45.1 0.3 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KFM82348.1 - 0.0027 17.3 0.1 0.0042 16.6 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RE_CfrBI PF09516.10 KFM82348.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 CfrBI restriction endonuclease DEAD PF00270.29 KFM82349.1 - 6.6e-39 133.5 0.2 1.6e-38 132.3 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM82349.1 - 1.8e-25 89.4 0.2 3.2e-23 82.2 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KFM82349.1 - 1.5e-07 31.5 0.0 2.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFM82349.1 - 0.00054 19.4 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit BACK PF07707.15 KFM82350.1 - 3.6e-05 23.8 0.3 6.2e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Fibrinogen_C PF00147.18 KFM82351.1 - 6.8e-62 209.1 9.8 7.9e-62 208.9 9.8 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Imm10 PF15588.6 KFM82351.1 - 0.039 14.1 0.1 0.079 13.1 0.1 1.5 1 1 0 1 1 1 0 Immunity protein 10 Fibrinogen_C PF00147.18 KFM82352.1 - 8.2e-56 189.3 10.8 9.9e-56 189.0 10.8 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 KFM82353.1 - 2.3e-61 207.4 9.8 2.7e-61 207.2 9.8 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain SNARE_assoc PF09335.11 KFM82354.1 - 8.7e-09 35.9 2.3 8.7e-09 35.9 2.3 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Ribosomal_S5_C PF03719.15 KFM82354.1 - 0.39 10.2 4.3 4.3 6.9 4.3 2.1 1 1 0 1 1 1 0 Ribosomal protein S5, C-terminal domain zf-H2C2_2 PF13465.6 KFM82355.1 - 1.5e-29 101.1 68.3 1.5e-10 41.0 0.6 9.6 10 0 0 10 10 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM82355.1 - 3.4e-27 93.3 78.5 1.7e-05 25.0 2.1 10.0 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM82355.1 - 5.2e-24 82.9 75.3 0.00044 20.8 0.3 10.1 10 0 0 10 10 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM82355.1 - 1.8e-13 50.4 50.8 0.00012 22.3 0.2 8.2 8 0 0 8 8 7 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM82355.1 - 2.3e-12 46.9 48.3 9.6e-05 22.6 0.1 8.5 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM82355.1 - 2.1e-06 27.6 0.0 2.1e-06 27.6 0.0 9.6 9 1 0 9 9 7 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFM82355.1 - 8.5e-06 26.0 36.6 0.031 14.6 3.9 5.6 4 2 1 5 5 5 3 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFM82355.1 - 0.0001 22.6 44.7 0.52 10.7 1.2 8.0 3 3 4 7 7 7 4 C2H2 type zinc-finger (2 copies) HypA PF01155.19 KFM82355.1 - 0.0054 16.7 15.1 3.6 7.7 2.1 4.5 3 1 1 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 KFM82355.1 - 0.0096 16.6 22.8 0.88 10.4 2.8 4.4 3 1 0 4 4 4 1 zinc-ribbon family zf-Di19 PF05605.12 KFM82355.1 - 0.014 15.7 45.7 0.82 10.0 1.6 6.8 6 0 0 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFM82355.1 - 0.014 15.7 12.2 1.1 9.6 0.0 5.8 4 2 3 7 7 7 0 BolA-like protein zf-C2H2_11 PF16622.5 KFM82355.1 - 0.021 14.6 0.6 0.021 14.6 0.6 7.0 8 0 0 8 8 7 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFM82355.1 - 0.047 13.5 0.2 0.047 13.5 0.2 9.2 10 0 0 10 10 8 0 C2H2-type zinc-finger domain Zn_ribbon_SprT PF17283.2 KFM82355.1 - 0.066 13.1 21.2 1.2 9.1 0.6 5.2 5 0 0 5 5 5 0 SprT-like zinc ribbon domain DZR PF12773.7 KFM82355.1 - 0.071 13.1 17.5 1.1 9.3 0.3 4.4 4 0 0 4 4 4 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KFM82355.1 - 0.11 12.6 24.4 1.5 9.0 0.3 5.7 5 2 1 6 6 6 0 Zinc ribbon domain zf-C2HE PF16278.5 KFM82355.1 - 0.13 12.7 0.1 0.13 12.7 0.1 8.9 4 3 4 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 KFM82355.1 - 0.22 11.4 19.1 2.3 8.1 0.5 6.5 4 2 3 7 7 7 0 C2H2 type zinc-finger (1 copy) zinc-ribbons_6 PF07191.12 KFM82355.1 - 0.23 11.5 29.2 1.4 9.0 1.5 5.2 3 2 1 4 4 4 0 zinc-ribbons zf_UBZ PF18439.1 KFM82355.1 - 1.2 8.8 19.1 5.8 6.6 0.1 6.5 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KFM82355.1 - 1.8 8.4 6.3 60 3.5 0.1 3.9 3 0 0 3 3 3 0 GAGA factor Desulfoferrod_N PF06397.12 KFM82355.1 - 3.6 7.3 7.8 3.1 7.5 0.0 4.2 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain Mut7-C PF01927.16 KFM82355.1 - 5 7.2 15.6 0.4 10.8 0.6 4.2 3 1 1 4 4 4 0 Mut7-C RNAse domain zf-C2HC_2 PF13913.6 KFM82355.1 - 5.1 7.1 19.0 6.7 6.7 0.0 5.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Spt46 PF17734.1 KFM82355.1 - 5.2 6.8 19.9 3.8 7.2 0.7 4.6 3 2 3 6 6 5 0 Spermatogenesis-associated protein 46 C1_4 PF07975.12 KFM82355.1 - 6.3 7.1 33.3 1.1 9.5 1.2 5.7 3 2 2 5 5 5 0 TFIIH C1-like domain FYDLN_acid PF09538.10 KFM82355.1 - 8.2 7.2 7.1 26 5.6 0.0 4.1 4 1 0 4 4 4 0 Protein of unknown function (FYDLN_acid) zf-C2H2 PF00096.26 KFM82356.1 - 2.9e-48 159.7 115.7 2.5e-05 24.4 2.8 12.4 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM82356.1 - 1.2e-47 158.3 106.0 3.4e-08 33.6 2.8 14.8 15 0 0 15 15 15 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM82356.1 - 5.5e-39 129.5 110.4 0.001 19.7 5.3 12.8 12 1 1 13 13 13 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM82356.1 - 1.6e-18 66.5 79.0 0.0021 18.3 3.6 12.4 12 0 0 12 12 12 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM82356.1 - 3.7e-11 43.0 90.8 0.004 17.5 1.9 12.0 12 0 0 12 12 12 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM82356.1 - 2.7e-05 24.0 11.6 0.00053 19.9 2.6 12.6 12 2 0 12 12 12 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM82356.1 - 0.0014 19.0 72.9 0.073 13.4 2.7 9.7 3 3 6 9 9 9 4 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFM82356.1 - 0.0014 18.4 0.0 0.0014 18.4 0.0 13.6 13 4 0 13 13 11 3 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KFM82356.1 - 0.0056 17.1 1.0 0.0056 17.1 1.0 10.5 4 3 6 10 10 10 2 C2HE / C2H2 / C2HC zinc-binding finger sCache_2 PF17200.4 KFM82356.1 - 0.087 12.7 0.3 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 Single Cache domain 2 zf-C2HC_2 PF13913.6 KFM82356.1 - 0.13 12.2 0.1 0.13 12.2 0.1 9.4 10 0 0 10 10 9 0 zinc-finger of a C2HC-type GAGA PF09237.11 KFM82356.1 - 0.63 9.9 29.0 0.12 12.2 0.5 7.0 5 3 3 8 8 8 0 GAGA factor BolA PF01722.18 KFM82356.1 - 1.6 9.1 10.1 18 5.7 0.1 4.9 3 3 2 5 5 5 0 BolA-like protein zf-MYST PF17772.1 KFM82356.1 - 3.2 7.4 43.6 0.11 12.1 0.7 8.6 7 2 1 8 8 8 0 MYST family zinc finger domain zf-C2H2_4 PF13894.6 KFM82357.1 - 1.1e-14 53.9 19.0 0.0026 18.5 0.3 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM82357.1 - 1.5e-14 53.5 20.4 0.001 19.4 0.4 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM82357.1 - 2.4e-07 30.6 14.2 0.0039 17.1 0.3 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM82357.1 - 3.2e-06 26.8 8.0 0.022 14.5 0.0 4.2 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KFM82357.1 - 9e-06 25.9 17.4 0.061 13.8 0.3 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2HE PF16278.5 KFM82357.1 - 0.00013 22.4 21.8 0.1 13.0 0.9 4.3 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KFM82357.1 - 0.00043 20.3 13.9 0.0026 17.8 2.1 3.4 2 1 1 3 3 3 1 Zinc ribbon domain zinc_ribbon_9 PF14369.6 KFM82357.1 - 0.00044 20.4 10.3 0.077 13.3 0.1 4.3 4 0 0 4 4 4 1 zinc-ribbon zinc_ribbon_15 PF17032.5 KFM82357.1 - 0.00051 20.7 6.7 0.24 12.2 0.8 2.4 1 1 1 2 2 2 2 zinc-ribbon family ADK_lid PF05191.14 KFM82357.1 - 0.0013 18.7 0.3 0.74 9.9 0.0 3.2 2 1 1 3 3 3 1 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 KFM82357.1 - 0.0013 19.0 12.6 0.23 11.8 0.0 4.5 5 0 0 5 5 4 1 Zinc-finger double-stranded RNA-binding DZR PF12773.7 KFM82357.1 - 0.0016 18.4 5.5 0.43 10.6 0.3 2.5 2 1 0 2 2 2 2 Double zinc ribbon TerY_C PF15616.6 KFM82357.1 - 0.0025 17.9 3.4 0.19 11.8 0.4 2.3 1 1 0 2 2 2 1 TerY-C metal binding domain zf-C2H2_2 PF12756.7 KFM82357.1 - 0.0025 18.1 12.8 0.074 13.4 0.9 3.1 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM82357.1 - 0.006 16.1 9.8 3.2 7.4 0.1 4.7 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KFM82357.1 - 0.0061 16.4 5.8 0.043 13.7 0.1 3.4 2 2 2 4 4 4 1 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KFM82357.1 - 0.039 14.3 11.3 0.23 11.8 1.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.6 KFM82357.1 - 0.068 13.1 12.3 0.62 10.0 3.1 3.2 3 0 0 3 3 3 0 Probable zinc-ribbon domain zinc_ribbon_4 PF13717.6 KFM82357.1 - 0.071 13.1 11.1 5.8 6.9 1.0 4.3 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.19 KFM82357.1 - 0.075 13.1 8.9 5.3 7.1 0.1 3.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-met PF12874.7 KFM82357.1 - 0.088 13.2 0.0 0.088 13.2 0.0 3.5 5 0 0 5 5 2 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 KFM82357.1 - 0.13 12.4 8.0 1.1 9.4 0.2 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) CpXC PF14353.6 KFM82357.1 - 0.19 11.8 8.7 33 4.6 0.1 4.1 2 1 0 3 3 3 0 CpXC protein DUF4428 PF14471.6 KFM82357.1 - 0.43 10.5 6.0 0.42 10.6 1.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-CHCC PF10276.9 KFM82357.1 - 0.63 10.1 0.1 0.63 10.1 0.1 2.6 3 0 0 3 3 2 0 Zinc-finger domain XPA_N PF01286.18 KFM82357.1 - 0.69 10.0 16.2 5.4 7.2 0.6 4.2 4 0 0 4 4 4 0 XPA protein N-terminal YhfH PF14149.6 KFM82357.1 - 0.91 9.6 7.1 13 5.9 0.1 4.0 4 0 0 4 4 4 0 YhfH-like protein C1_1 PF00130.22 KFM82357.1 - 1.1 9.2 13.6 1.6 8.7 2.4 3.8 1 1 3 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.6 KFM82357.1 - 1.8 8.1 9.6 8.5 5.9 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFM82357.1 - 3.1 7.9 10.5 3.4e+02 1.3 10.5 2.9 1 1 0 1 1 1 0 zinc-ribbons FYDLN_acid PF09538.10 KFM82357.1 - 3.5 8.3 5.2 41 4.9 0.1 3.5 1 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zf_ZIC PF18366.1 KFM82357.1 - 4.6 7.4 5.9 7.4 6.8 0.1 3.2 1 1 2 3 3 3 0 Zic proteins zinc finger domain HNH PF01844.23 KFM82357.1 - 8 6.7 8.4 48 4.2 0.1 3.8 4 0 0 4 4 4 0 HNH endonuclease HalOD2 PF18547.1 KFM82357.1 - 10 6.2 7.8 48 4.0 0.3 3.7 4 0 0 4 4 4 0 Halobacterial output domain 2 zf-CCHC PF00098.23 KFM82358.1 - 0.01 15.9 1.9 0.027 14.5 1.9 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2_2 PF13465.6 KFM82359.1 - 8.5e-18 63.9 70.4 2.2e-07 31.0 0.8 11.0 11 0 0 11 11 11 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFM82359.1 - 2.8e-16 58.9 50.5 2.7e-06 27.0 4.9 7.6 6 0 0 6 6 6 5 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFM82359.1 - 3.1e-11 43.1 85.3 0.012 16.4 0.8 12.2 12 0 0 12 12 12 8 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM82359.1 - 1.5e-07 31.5 84.4 0.021 15.3 2.7 11.5 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM82359.1 - 0.039 14.2 0.6 0.039 14.2 0.6 8.1 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding Ta0938 PF11494.8 KFM82359.1 - 0.061 13.6 0.9 4.7 7.5 0.1 3.3 2 0 0 2 2 2 0 Ta0938 zf-C2H2_6 PF13912.6 KFM82359.1 - 0.064 13.3 0.4 0.064 13.3 0.4 9.5 11 2 0 11 11 11 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFM82359.1 - 0.15 12.4 0.1 0.15 12.4 0.1 7.5 3 1 3 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM82359.1 - 0.15 11.9 0.0 0.15 11.9 0.0 5.7 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) M20_dimer PF07687.14 KFM82360.1 - 3e-11 43.2 0.0 5.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KFM82360.1 - 1.1e-08 35.0 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 GFO_IDH_MocA PF01408.22 KFM82361.1 - 1.8e-17 64.3 0.1 5.7e-17 62.6 0.0 1.8 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 KFM82361.1 - 0.012 15.6 0.0 0.031 14.4 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KFM82361.1 - 0.027 15.0 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Antimicrobial22 PF16047.5 KFM82361.1 - 2.4 8.1 4.7 4.9 7.1 0.4 2.8 2 0 0 2 2 2 0 Frog antimicrobial peptide Ank_5 PF13857.6 KFM82362.1 - 3.5e-24 84.5 1.2 9.1e-12 45.0 0.5 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM82362.1 - 7.4e-20 71.3 0.3 9.5e-12 45.4 0.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFM82362.1 - 2.1e-19 69.0 0.6 5.2e-07 29.8 0.2 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFM82362.1 - 2.1e-16 60.1 0.8 2.8e-07 31.0 0.2 4.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM82362.1 - 9.3e-14 50.2 0.1 0.0027 18.0 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat E2F_TDP PF02319.20 KFM82363.1 - 1.3e-20 73.2 0.2 5e-20 71.3 0.0 2.1 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 KFM82363.1 - 3.1e-14 53.1 1.2 3.1e-14 53.1 1.2 1.8 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain KH_8 PF17903.1 KFM82363.1 - 0.07 13.2 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Krr1 KH1 domain Hormone_recep PF00104.30 KFM82365.1 - 1.5e-18 67.1 1.2 2.5e-18 66.4 1.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Hormone_recep PF00104.30 KFM82366.1 - 1.3e-07 31.4 0.3 2e-07 30.8 0.3 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nudc_N PF14050.6 KFM82366.1 - 0.14 12.2 3.0 0.58 10.2 0.1 2.4 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. DUF829 PF05705.14 KFM82367.1 - 1.5e-41 142.9 0.2 2.1e-41 142.4 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 KFM82367.1 - 0.013 15.0 0.1 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KFM82367.1 - 0.051 13.1 0.6 0.093 12.3 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KFM82367.1 - 0.13 11.5 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Acetyltransf_1 PF00583.25 KFM82368.1 - 3.3e-07 30.5 0.0 5.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM82368.1 - 9.9e-07 28.8 0.1 2.5e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM82368.1 - 9.6e-06 25.9 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFM82368.1 - 0.0017 18.4 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KFM82368.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 KFM82368.1 - 0.14 12.3 0.1 0.66 10.1 0.1 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 KFM82369.1 - 8.3e-13 48.3 0.0 2.1e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM82369.1 - 3e-07 30.7 0.1 9.9e-06 25.8 0.1 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM82369.1 - 1.7e-05 24.7 0.0 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM82369.1 - 0.00029 21.2 0.1 0.0012 19.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFM82369.1 - 0.18 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase An_peroxidase PF03098.15 KFM82370.1 - 1.1e-27 96.8 0.7 1.8e-27 96.2 0.1 1.6 2 0 0 2 2 2 1 Animal haem peroxidase NAD_binding_6 PF08030.12 KFM82370.1 - 6.4e-25 88.1 0.2 2.4e-24 86.2 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFM82370.1 - 1.8e-18 66.8 9.0 1.8e-18 66.8 9.0 1.7 2 0 0 2 2 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFM82370.1 - 6.3e-15 55.2 0.0 1.5e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain EF-hand_1 PF00036.32 KFM82370.1 - 1.6e-13 49.1 9.8 5.3e-07 28.7 0.4 4.0 4 0 0 4 4 3 2 EF hand EF-hand_7 PF13499.6 KFM82370.1 - 1.8e-12 47.5 8.3 1.7e-05 25.1 1.7 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM82370.1 - 2.7e-11 42.4 3.1 2.4e-06 26.8 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM82370.1 - 2.3e-08 33.3 11.9 1.5e-05 24.5 0.2 3.8 5 0 0 5 5 3 2 EF-hand domain EF-hand_8 PF13833.6 KFM82370.1 - 1.2e-06 28.3 5.9 0.00046 20.0 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair DUF2600 PF10776.9 KFM82370.1 - 0.031 13.2 0.0 1.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) SPARC_Ca_bdg PF10591.9 KFM82370.1 - 0.061 13.6 1.2 9.2 6.6 0.1 3.0 2 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.11 KFM82370.1 - 0.073 13.5 0.1 0.8 10.2 0.0 2.6 2 1 0 2 2 2 0 EF-hand EF-hand_4 PF12763.7 KFM82370.1 - 0.16 11.9 3.1 2.2 8.3 0.4 2.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand An_peroxidase PF03098.15 KFM82371.1 - 5e-17 61.7 0.0 5.6e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 KFM82372.1 - 4.3e-67 226.9 0.0 4.8e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase DUF1133 PF06576.11 KFM82372.1 - 0.047 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) Stathmin PF00836.19 KFM82373.1 - 0.017 15.1 13.4 0.029 14.3 13.4 1.4 1 1 0 1 1 1 0 Stathmin family V_ATPase_I PF01496.19 KFM82373.1 - 0.079 10.9 6.9 0.086 10.7 6.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.5 KFM82373.1 - 2.4 7.5 11.8 2.6 7.4 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) p450 PF00067.22 KFM82374.1 - 1.3e-87 294.5 0.1 1.4e-87 294.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM82375.1 - 9.5e-28 97.1 0.0 1.1e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM82376.1 - 2.2e-62 211.3 0.0 2.9e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GAS PF13851.6 KFM82377.1 - 0.00043 19.7 21.2 0.00043 19.7 21.2 3.3 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 KFM82377.1 - 0.00071 19.6 12.2 0.00071 19.6 12.2 5.2 2 1 2 4 4 4 2 BRE1 E3 ubiquitin ligase Nup54 PF13874.6 KFM82377.1 - 0.0055 16.8 3.2 0.0055 16.8 3.2 3.6 2 1 1 4 4 4 1 Nucleoporin complex subunit 54 DUF948 PF06103.11 KFM82377.1 - 0.8 10.0 18.2 1.7 9.0 1.3 3.9 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 KFM82377.1 - 1.9 8.9 26.1 0.39 11.2 2.7 5.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 KFM82377.1 - 2.3 8.7 59.5 4.4 7.9 7.8 4.3 2 1 2 4 4 4 0 Apg6 coiled-coil region DUF4201 PF13870.6 KFM82377.1 - 3.5 7.3 55.6 0.056 13.2 7.3 4.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4201) Filament PF00038.21 KFM82377.1 - 6.5 6.2 44.9 4.1 6.9 4.2 3.4 2 1 2 4 4 4 0 Intermediate filament protein Taxilin PF09728.9 KFM82377.1 - 6.6 5.8 50.6 0.053 12.7 7.9 3.7 2 1 2 4 4 4 0 Myosin-like coiled-coil protein DUF4686 PF15742.5 KFM82377.1 - 8.6 5.4 55.6 0.024 13.8 19.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) Lysyl_oxidase PF01186.17 KFM82378.1 - 4e-93 310.8 4.3 5.9e-93 310.2 4.3 1.3 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.18 KFM82378.1 - 1.4e-50 169.9 19.9 5.4e-29 100.6 0.3 4.0 4 0 0 4 4 4 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFM82378.1 - 4.8e-10 39.8 1.4 0.00021 21.8 0.1 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFM82378.1 - 0.042 14.4 0.2 0.39 11.3 0.1 2.5 2 0 0 2 2 2 0 Hepsin, SRCR domain CARDB PF07705.11 KFM82378.1 - 0.11 12.8 0.1 0.36 11.1 0.0 2.0 3 0 0 3 3 3 0 CARDB DUF2353 PF09789.9 KFM82380.1 - 9e-33 114.0 9.0 3.5e-31 108.7 4.5 2.0 2 0 0 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) PEP-utilisers_N PF05524.13 KFM82380.1 - 0.17 12.0 1.2 0.28 11.4 0.7 1.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Suppressor_APC PF11414.8 KFM82380.1 - 0.27 11.3 3.2 0.46 10.6 3.2 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DUF2353 PF09789.9 KFM82381.1 - 4.1e-15 56.0 0.3 5.4e-15 55.6 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Occludin_ELL PF07303.13 KFM82381.1 - 0.0061 17.3 0.6 0.0083 16.8 0.6 1.1 1 0 0 1 1 1 1 Occludin homology domain CENP-F_leu_zip PF10473.9 KFM82381.1 - 0.0072 16.4 0.9 0.009 16.0 0.9 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Opiods_neuropep PF01160.18 KFM82381.1 - 0.022 14.9 0.6 0.038 14.1 0.6 1.4 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide DUF4201 PF13870.6 KFM82381.1 - 0.046 13.4 3.2 0.056 13.2 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Amino_oxidase PF01593.24 KFM82382.1 - 9.1e-52 176.8 0.0 1.1e-51 176.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DUF2087 PF09860.9 KFM82382.1 - 0.17 12.0 1.3 2.5 8.3 0.3 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) Sec15 PF04091.12 KFM82384.1 - 2.2e-97 326.3 4.6 2.2e-97 326.3 4.6 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 KFM82384.1 - 0.028 14.3 0.6 0.028 14.3 0.6 3.3 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain COG2 PF06148.11 KFM82384.1 - 0.074 13.1 2.8 0.33 11.0 1.7 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Antimicrobial25 PF16839.5 KFM82384.1 - 0.1 12.7 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 Nematode antimicrobial peptide zf-H2C2_2 PF13465.6 KFM82386.1 - 5.3e-40 134.1 31.3 4.5e-08 33.2 0.7 6.1 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM82386.1 - 1.6e-22 78.6 34.7 0.00019 21.7 0.9 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM82386.1 - 7.1e-20 70.0 34.5 0.00054 20.6 0.6 5.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM82386.1 - 5.5e-12 45.4 30.9 0.00068 19.6 0.4 5.5 5 1 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM82386.1 - 1.3e-07 31.3 16.9 0.21 11.4 0.0 5.8 6 0 0 6 6 6 4 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 KFM82386.1 - 1.4e-07 31.2 15.7 0.14 12.0 0.2 5.0 1 1 4 5 5 5 3 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 KFM82386.1 - 1.8e-06 28.2 32.2 0.065 13.6 0.6 5.3 5 0 0 5 5 5 4 Zinc-finger of C2H2 type GAGA PF09237.11 KFM82386.1 - 1e-05 25.2 6.8 2 8.3 0.0 4.8 1 1 4 5 5 5 3 GAGA factor BolA PF01722.18 KFM82386.1 - 3.2e-05 24.1 3.9 0.6 10.4 0.4 4.0 1 1 3 4 4 4 2 BolA-like protein C1_1 PF00130.22 KFM82386.1 - 3.6e-05 23.5 21.3 0.17 11.8 0.3 4.9 2 2 2 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 KFM82386.1 - 0.00027 20.8 17.7 0.64 10.0 0.2 5.5 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFM82386.1 - 0.00027 21.1 20.9 0.028 14.7 0.2 5.3 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 KFM82386.1 - 0.00032 20.7 19.2 4.6 7.4 0.1 5.3 5 0 0 5 5 5 1 DBF zinc finger zf-FPG_IleRS PF06827.14 KFM82386.1 - 0.001 18.9 13.1 0.16 11.9 0.1 4.9 5 0 0 5 5 5 1 Zinc finger found in FPG and IleRS zf-C2H2_2 PF12756.7 KFM82386.1 - 0.0012 19.1 27.5 0.75 10.2 0.5 5.0 1 1 4 5 5 5 3 C2H2 type zinc-finger (2 copies) YyzF PF14116.6 KFM82386.1 - 0.0015 18.5 11.1 13 5.9 0.1 5.1 5 0 0 5 5 5 0 YyzF-like protein zf-C2H2_11 PF16622.5 KFM82386.1 - 0.0023 17.7 22.7 0.36 10.6 0.3 5.2 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM82386.1 - 0.0027 17.7 14.6 3.4 7.8 0.7 5.0 4 1 1 5 5 5 1 Sec23/Sec24 zinc finger zf-Di19 PF05605.12 KFM82386.1 - 0.0029 17.9 26.5 0.11 12.8 4.4 4.2 1 1 4 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-HIT PF04438.16 KFM82386.1 - 0.0029 17.4 26.4 0.42 10.5 0.6 5.2 5 0 0 5 5 5 2 HIT zinc finger zf-Paramyx-P PF13008.7 KFM82386.1 - 0.0061 16.0 9.4 22 4.6 0.0 5.0 5 0 0 5 5 5 0 Zinc-binding domain of Paramyxoviridae V protein DUF2256 PF10013.9 KFM82386.1 - 0.0095 16.0 12.2 23 5.2 0.8 5.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFM82386.1 - 0.016 14.8 20.6 6.8 6.4 0.2 5.0 2 2 3 5 5 5 0 MYST family zinc finger domain zf-RRPl_C4 PF17026.5 KFM82386.1 - 0.029 14.5 15.8 0.05 13.7 6.9 2.9 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Tox-HNH-HHH PF15637.6 KFM82386.1 - 0.046 13.9 0.1 0.8 9.9 0.0 2.2 1 1 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF4990 PF16380.5 KFM82386.1 - 0.072 13.2 1.3 28 4.8 0.1 3.9 4 1 1 5 5 4 0 Domain of unknown function PqqA PF08042.11 KFM82386.1 - 0.096 12.8 2.4 1.7e+02 2.5 0.0 4.4 5 0 0 5 5 5 0 PqqA family DUF2039 PF10217.9 KFM82386.1 - 0.12 12.8 14.8 0.67 10.3 1.8 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2039) DUF5330 PF17264.2 KFM82386.1 - 0.12 12.4 9.8 51 4.0 0.0 5.0 5 0 0 5 5 5 0 Family of unknown function (DUF5330) Zf_RING PF16744.5 KFM82386.1 - 0.2 11.8 20.8 3.5 7.8 1.0 4.8 1 1 4 5 5 5 0 KIAA1045 RING finger zf-C2H2_8 PF15909.5 KFM82386.1 - 0.29 11.5 19.6 0.43 10.9 2.8 3.7 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-RRN7 PF11781.8 KFM82386.1 - 0.3 10.8 14.8 8.1 6.2 0.1 5.0 5 0 0 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-trcl PF13451.6 KFM82386.1 - 0.52 10.2 12.3 40 4.2 0.1 4.9 5 0 0 5 5 5 0 Probable zinc-ribbon domain ADK_lid PF05191.14 KFM82386.1 - 1.5 8.9 16.5 5.7 7.0 1.9 3.5 1 1 2 3 3 3 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFM82386.1 - 1.9 9.3 17.2 16 6.3 6.0 3.0 1 1 0 2 2 2 0 zinc-ribbon family RecR PF02132.15 KFM82386.1 - 2.9 7.5 20.3 16 5.1 0.1 4.8 3 2 0 3 3 3 0 RecR protein FYVE PF01363.21 KFM82386.1 - 4.4 7.5 23.5 1.8e+04 -4.0 23.5 3.3 1 1 0 1 1 0 0 FYVE zinc finger TerY_C PF15616.6 KFM82386.1 - 4.5 7.4 10.3 6.9 6.8 0.3 2.9 1 1 2 3 3 3 0 TerY-C metal binding domain DUF5641 PF18701.1 KFM82388.1 - 9.5e-30 102.6 0.4 2e-29 101.6 0.4 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5641) PCB_OB PF17092.5 KFM82388.1 - 0.053 14.3 0.0 1.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain Astacin PF01400.24 KFM82389.1 - 9.4e-27 93.9 0.0 1.1e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFM82389.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Matrixin Metallopep PF12044.8 KFM82389.1 - 0.045 12.4 0.1 0.06 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.9 KFM82389.1 - 0.049 12.6 0.1 0.058 12.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M8 PF01457.16 KFM82389.1 - 0.1 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin Reprolysin_3 PF13582.6 KFM82389.1 - 0.16 12.5 1.6 0.26 11.8 1.6 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFM82389.1 - 0.19 11.6 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like WW PF00397.26 KFM82392.1 - 3e-20 72.0 14.7 6.7e-11 42.1 3.6 2.5 2 0 0 2 2 2 2 WW domain FF PF01846.19 KFM82392.1 - 1.5e-13 50.6 0.1 1.5e-13 50.6 0.1 1.9 2 0 0 2 2 2 1 FF domain Glyco_hyd_101C PF17451.2 KFM82392.1 - 0.053 13.8 5.4 2.2 8.6 0.5 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain LUD_dom PF02589.15 KFM82392.1 - 0.13 12.0 0.6 0.25 11.0 0.6 1.4 1 0 0 1 1 1 0 LUD domain FF PF01846.19 KFM82393.1 - 2.8e-27 94.6 4.1 2.7e-08 33.9 0.0 4.9 5 0 0 5 5 5 4 FF domain Spherulin4 PF12138.8 KFM82393.1 - 0.015 15.0 0.3 0.048 13.3 0.2 2.0 1 1 0 1 1 1 0 Spherulation-specific family 4 Arc_PepC_II PF06847.11 KFM82393.1 - 6.8 7.3 14.4 0.32 11.5 0.5 3.7 3 1 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II NUDIX PF00293.28 KFM82394.1 - 1.8e-09 37.7 0.0 2.4e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain SSF PF00474.17 KFM82395.1 - 1.1e-41 143.1 29.1 1.7e-41 142.4 27.3 1.9 2 0 0 2 2 2 1 Sodium:solute symporter family Na_K-ATPase PF00287.18 KFM82396.1 - 1.7e-55 188.2 0.0 1.9e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain VID27_N PF17748.1 KFM82396.1 - 0.11 12.3 0.0 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 VID27 N-terminal region AMOP PF03782.17 KFM82398.1 - 7.1e-43 146.2 5.8 1.4e-42 145.2 5.8 1.5 1 0 0 1 1 1 1 AMOP domain NIDO PF06119.14 KFM82398.1 - 2.8e-17 63.4 0.2 2.5e-15 57.2 0.1 2.8 2 0 0 2 2 2 1 Nidogen-like VWD PF00094.25 KFM82398.1 - 5e-16 59.3 0.0 6.1e-15 55.8 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type D domain Sushi PF00084.20 KFM82398.1 - 6.2e-08 33.1 1.3 1.7e-07 31.7 1.3 1.8 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) TIG PF01833.24 KFM82398.1 - 6e-06 26.2 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain BolA PF01722.18 KFM82400.1 - 5.9e-27 93.8 0.2 8.2e-27 93.3 0.2 1.2 1 0 0 1 1 1 1 BolA-like protein Forkhead PF00250.18 KFM82401.1 - 2.1e-28 98.4 0.0 4.2e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Phosphodiest PF01663.22 KFM82403.1 - 9.5e-39 134.0 1.3 1.1e-38 133.8 1.3 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFM82403.1 - 0.011 15.1 0.2 0.15 11.4 0.0 2.0 1 1 1 2 2 2 0 Sulfatase Glyco_hydro_47 PF01532.20 KFM82404.1 - 3.7e-26 92.1 0.1 6.3e-26 91.3 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 TrpBP PF02081.15 KFM82405.1 - 0.0097 15.7 0.1 0.1 12.4 0.0 2.2 1 1 1 2 2 2 1 Tryptophan RNA-binding attenuator protein DUF4371 PF14291.6 KFM82405.1 - 0.023 14.4 0.1 0.042 13.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4371) DUF1138 PF06592.13 KFM82406.1 - 0.0071 16.4 0.0 0.0083 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1138) T-box PF00907.22 KFM82407.1 - 1.9e-14 54.4 0.0 2.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 T-box T-box PF00907.22 KFM82408.1 - 2.4e-24 86.6 0.9 4.1e-24 85.9 0.9 1.4 1 0 0 1 1 1 1 T-box CRAL_TRIO_2 PF13716.6 KFM82409.1 - 5e-36 123.9 1.4 9.5e-36 123.0 1.4 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 KFM82409.1 - 1.1e-23 83.5 0.0 5.2e-23 81.3 0.0 2.0 2 0 0 2 2 2 1 Macro domain CRAL_TRIO PF00650.20 KFM82409.1 - 1e-09 38.3 0.2 2.1e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain SLC35F PF06027.12 KFM82411.1 - 8.4e-07 28.8 3.2 1.3e-06 28.2 3.2 1.2 1 0 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 KFM82411.1 - 0.001 18.4 2.9 0.0015 17.9 2.9 1.1 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 KFM82411.1 - 0.0074 16.5 7.6 0.022 14.9 7.6 1.9 1 1 0 1 1 1 1 EamA-like transporter family DUF3270 PF11674.8 KFM82411.1 - 0.044 14.0 1.5 0.09 13.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) BAP PF06639.11 KFM82411.1 - 0.063 13.6 0.4 0.13 12.6 0.4 1.5 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) Cation_efflux PF01545.21 KFM82412.1 - 6.8e-29 101.0 9.1 9.1e-29 100.6 9.1 1.2 1 0 0 1 1 1 1 Cation efflux family XPA_C PF05181.12 KFM82412.1 - 0.017 15.0 0.2 0.051 13.6 0.0 1.9 2 0 0 2 2 2 0 XPA protein C-terminus Ion_trans_N PF08412.10 KFM82412.1 - 0.66 9.6 4.4 0.13 11.9 0.3 2.0 2 0 0 2 2 2 0 Ion transport protein N-terminal IFT20 PF14931.6 KFM82412.1 - 3.1 8.0 12.0 0.13 12.4 5.6 1.9 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 CDP-OH_P_transf PF01066.21 KFM82416.1 - 0.24 12.2 0.8 0.42 11.4 0.8 1.4 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase LisH_2 PF16045.5 KFM82417.1 - 1.6e-07 30.3 1.2 2.9e-07 29.4 0.1 2.1 3 0 0 3 3 3 1 LisH DUF3435 PF11917.8 KFM82417.1 - 0.02 13.8 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF3879 PF12995.7 KFM82417.1 - 0.12 12.1 0.0 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) HIP1_clath_bdg PF16515.5 KFM82418.1 - 0.71 10.5 41.8 0.73 10.5 10.8 3.6 1 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 KFM82418.1 - 3.1 7.1 20.8 1.2 8.4 6.5 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 KFM82418.1 - 3.7 6.9 43.6 2 7.8 7.3 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF1284 PF06935.11 KFM82418.1 - 5.4 7.5 10.5 1.5 9.3 3.6 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1284) GLE1 PF07817.13 KFM82419.1 - 0.005 16.1 0.7 0.0055 15.9 0.7 1.1 1 0 0 1 1 1 1 GLE1-like protein PRKG1_interact PF15898.5 KFM82419.1 - 0.0073 17.2 0.5 0.014 16.3 0.2 1.5 1 1 0 1 1 1 1 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.8 KFM82419.1 - 0.02 15.1 1.6 0.14 12.4 0.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.11 KFM82419.1 - 0.027 15.0 0.8 0.075 13.6 0.7 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal NRBF2 PF08961.10 KFM82419.1 - 0.041 13.5 1.8 0.048 13.3 0.4 1.7 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DIRP PF06584.13 KFM82419.1 - 0.057 13.6 2.5 2.4 8.4 0.5 2.1 1 1 1 2 2 2 0 DIRP TSC22 PF01166.18 KFM82419.1 - 0.17 12.2 1.7 27 5.1 0.0 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family TolA_bind_tri PF16331.5 KFM82419.1 - 0.19 11.8 3.7 1.4 9.1 1.9 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 KFM82419.1 - 0.35 10.9 5.2 8.6 6.4 1.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4094 PF13334.6 KFM82419.1 - 0.71 10.3 2.9 1.4 9.4 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) UPF0242 PF06785.11 KFM82419.1 - 2.6 8.1 8.7 2.9 8.0 3.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 KFM82419.1 - 6.5 6.8 8.7 7.7 6.6 1.0 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Condensin2nSMC PF12422.8 KFM82422.1 - 0.0037 17.5 1.1 0.0075 16.5 1.1 1.6 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit DUF445 PF04286.12 KFM82422.1 - 0.24 11.1 22.7 0.017 14.9 15.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF1664 PF07889.12 KFM82422.1 - 2.6 8.1 21.2 0.27 11.3 2.1 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Phasin PF05597.11 KFM82422.1 - 5.8 6.9 17.2 0.2 11.7 0.5 3.9 1 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Enkurin PF13864.6 KFM82422.1 - 7.2 7.1 21.9 20 5.7 4.5 3.4 3 0 0 3 3 3 0 Calmodulin-binding DLP_helical PF18709.1 KFM82422.1 - 8.7 5.4 25.3 3.6 6.7 10.2 2.6 1 1 1 2 2 2 0 Dynamin-like helical domain TIP49 PF06068.13 KFM82423.1 - 1.6e-150 501.2 3.0 2.4e-150 500.6 3.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFM82423.1 - 6.3e-27 93.5 0.4 1.9e-26 92.0 0.4 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KFM82423.1 - 8.3e-09 36.0 1.6 7.3e-06 26.4 0.1 3.1 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM82423.1 - 1.2e-06 28.6 0.3 0.0016 18.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 KFM82423.1 - 1.2e-06 28.1 0.2 2.4e-06 27.1 0.2 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RuvB_N PF05496.12 KFM82423.1 - 2e-06 27.6 2.3 0.0052 16.5 0.1 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KFM82423.1 - 5.4e-05 23.0 1.0 0.084 12.6 0.1 3.3 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_19 PF13245.6 KFM82423.1 - 8.2e-05 23.0 2.2 0.0032 17.8 2.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM82423.1 - 8.7e-05 23.0 0.2 0.00033 21.1 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM82423.1 - 0.00013 22.3 0.7 0.19 12.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KFM82423.1 - 0.00065 19.1 0.5 0.035 13.5 0.3 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KFM82423.1 - 0.00083 18.8 0.2 0.0016 17.8 0.2 1.6 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 KFM82423.1 - 0.0013 18.4 0.1 0.0026 17.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM82423.1 - 0.0034 16.7 0.2 0.0066 15.7 0.2 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 KFM82423.1 - 0.0048 16.8 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 KFM82423.1 - 0.0052 16.1 0.1 0.0096 15.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 KFM82423.1 - 0.0069 16.8 0.9 0.025 15.0 0.4 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFM82423.1 - 0.0069 16.1 0.5 0.19 11.4 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFM82423.1 - 0.0077 16.8 0.6 0.0077 16.8 0.6 1.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFM82423.1 - 0.011 15.3 0.1 0.093 12.2 0.1 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFM82423.1 - 0.014 15.6 0.1 0.025 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KFM82423.1 - 0.028 14.4 1.1 2.2 8.3 0.2 2.5 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 KFM82423.1 - 0.035 14.1 1.4 0.071 13.1 0.1 2.1 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KFM82423.1 - 0.036 13.8 0.5 0.088 12.6 0.5 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM82423.1 - 0.057 13.9 0.7 0.14 12.6 0.7 1.7 1 0 0 1 1 1 0 ABC transporter USP7_ICP0_bdg PF12436.8 KFM82423.1 - 0.071 12.4 0.1 0.15 11.3 0.1 1.5 1 1 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 Sigma54_activ_2 PF14532.6 KFM82423.1 - 0.077 13.1 0.0 5.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.13 KFM82424.1 - 0.0069 15.6 0.2 0.0083 15.4 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain Peptidase_C14 PF00656.22 KFM82425.1 - 1.2e-30 107.2 0.3 2.7e-30 106.1 0.3 1.5 1 1 0 1 1 1 1 Caspase domain CARD_2 PF16739.5 KFM82425.1 - 0.061 13.3 0.0 0.67 10.0 0.0 2.4 1 1 0 1 1 1 0 Caspase recruitment domain CARD PF00619.21 KFM82425.1 - 0.086 12.9 0.1 2.7 8.1 0.0 2.9 2 1 0 2 2 2 0 Caspase recruitment domain Kinesin PF00225.23 KFM82426.1 - 3.5e-79 266.2 0.5 3.8e-79 266.0 0.5 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM82426.1 - 1.2e-09 38.3 0.0 3.3e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DUF812 PF05667.11 KFM82427.1 - 1.2e-07 31.0 20.5 1.4e-07 30.8 20.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Uso1_p115_C PF04871.13 KFM82427.1 - 5.2e-05 23.6 40.2 8.6e-05 22.9 21.0 2.3 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region KASH_CCD PF14662.6 KFM82427.1 - 0.00062 19.6 39.7 0.0013 18.6 17.5 3.1 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 KFM82427.1 - 0.0016 17.2 28.6 0.0022 16.7 28.6 1.1 1 0 0 1 1 1 1 AAA domain ALIX_LYPXL_bnd PF13949.6 KFM82427.1 - 0.0047 16.3 29.7 0.022 14.0 12.1 2.1 1 1 1 2 2 2 2 ALIX V-shaped domain binding to HIV Filament PF00038.21 KFM82427.1 - 0.0089 15.6 32.3 0.31 10.6 10.1 2.7 1 1 0 2 2 2 2 Intermediate filament protein ATG16 PF08614.11 KFM82427.1 - 0.014 15.6 41.2 0.36 11.0 11.7 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KFM82427.1 - 0.015 15.9 42.3 0.095 13.2 24.1 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 KFM82427.1 - 0.023 14.8 42.2 0.44 10.6 13.4 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KFM82427.1 - 0.025 14.6 40.3 0.21 11.6 10.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KFM82427.1 - 0.03 14.4 40.3 0.075 13.1 3.7 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein AIP3 PF03915.13 KFM82427.1 - 0.037 13.1 18.9 0.055 12.5 18.9 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 HOOK PF05622.12 KFM82427.1 - 0.057 11.6 33.6 0.076 11.2 33.6 1.1 1 0 0 1 1 1 0 HOOK protein Vac_Fusion PF02346.16 KFM82427.1 - 0.11 12.2 7.7 3 7.6 0.4 4.2 2 1 2 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Microtub_bd PF16796.5 KFM82427.1 - 0.15 12.0 0.5 0.15 12.0 0.5 3.0 2 1 0 2 2 2 0 Microtubule binding Jnk-SapK_ap_N PF09744.9 KFM82427.1 - 0.2 11.9 36.1 0.45 10.7 17.4 2.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 KFM82427.1 - 0.2 11.0 28.2 1.5 8.1 25.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PspA_IM30 PF04012.12 KFM82427.1 - 0.24 10.9 33.0 0.018 14.6 17.2 3.1 1 1 2 3 3 3 0 PspA/IM30 family Lectin_N PF03954.14 KFM82427.1 - 0.25 11.1 23.0 2.2 8.0 5.9 3.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain THOC7 PF05615.13 KFM82427.1 - 0.26 11.6 31.8 0.028 14.7 17.7 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 MAD PF05557.13 KFM82427.1 - 0.32 9.3 38.2 0.79 8.0 38.2 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein DivIC PF04977.15 KFM82427.1 - 0.33 10.7 35.6 1.9 8.3 9.4 4.5 1 1 5 6 6 6 0 Septum formation initiator CC2-LZ PF16516.5 KFM82427.1 - 0.39 11.1 31.2 1.1 9.7 7.8 3.2 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator YabA PF06156.13 KFM82427.1 - 0.4 11.4 34.1 0.048 14.3 6.6 3.3 1 1 2 3 3 3 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 KFM82427.1 - 0.49 10.5 39.8 1.9 8.6 11.0 3.5 1 1 2 3 3 3 0 Tropomyosin like DUF489 PF04356.12 KFM82427.1 - 0.63 10.0 18.3 3.1 7.8 7.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF489) SHE3 PF17078.5 KFM82427.1 - 0.69 9.6 35.6 3.5 7.3 35.6 1.9 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Csm1_N PF18504.1 KFM82427.1 - 0.83 10.0 35.1 0.8 10.1 9.4 4.4 1 1 3 4 4 4 0 Csm1 N-terminal domain PRKG1_interact PF15898.5 KFM82427.1 - 0.89 10.5 36.9 0.14 13.1 16.5 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF724 PF05266.14 KFM82427.1 - 1.1 9.0 27.4 0.58 9.9 9.2 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF724) BRE1 PF08647.11 KFM82427.1 - 1.2 9.3 42.0 0.14 12.2 1.4 3.4 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KFM82427.1 - 1.2 9.3 30.4 0.49 10.6 15.1 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family GAS PF13851.6 KFM82427.1 - 1.3 8.3 40.5 0.87 8.9 18.8 2.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ABC_tran_CTD PF16326.5 KFM82427.1 - 1.4 9.2 32.1 0.036 14.3 7.6 3.8 1 1 3 4 4 4 0 ABC transporter C-terminal domain DUF3450 PF11932.8 KFM82427.1 - 1.6 8.0 34.1 0.59 9.4 9.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 KFM82427.1 - 1.7 7.6 34.4 0.066 12.3 19.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KFM82427.1 - 1.9 7.3 38.4 0.58 9.0 16.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein HMMR_N PF15905.5 KFM82427.1 - 2.2 7.7 39.5 0.069 12.6 12.8 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 KFM82427.1 - 2.5 7.5 36.1 1.7 8.1 12.8 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 CLZ PF16526.5 KFM82427.1 - 2.7 8.4 32.5 0.33 11.3 6.0 4.5 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAUS-augmin3 PF14932.6 KFM82427.1 - 3.3 7.2 38.1 0.76 9.3 18.3 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Endotoxin_N PF03945.14 KFM82427.1 - 3.4 7.3 8.4 0.38 10.4 2.3 2.2 1 1 0 2 2 2 0 delta endotoxin, N-terminal domain Rho_Binding PF08912.11 KFM82427.1 - 3.8 8.4 34.8 10 7.0 0.2 4.6 3 2 1 4 4 4 0 Rho Binding FAM184 PF15665.5 KFM82427.1 - 4.1 7.1 32.6 68 3.1 26.1 2.9 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF1664 PF07889.12 KFM82427.1 - 4.2 7.4 21.4 14 5.7 3.5 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CENP-Q PF13094.6 KFM82427.1 - 4.7 7.4 40.9 0.29 11.3 13.8 3.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF641 PF04859.12 KFM82427.1 - 5.3 7.4 25.5 5 7.5 9.3 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF745 PF05335.13 KFM82427.1 - 5.5 6.7 24.7 0.66 9.7 8.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) YscO PF07321.12 KFM82427.1 - 5.9 6.8 31.5 0.55 10.2 13.2 3.1 1 1 2 3 3 3 0 Type III secretion protein YscO HAP1_N PF04849.13 KFM82427.1 - 6.9 5.8 36.3 80 2.3 36.4 2.2 1 1 0 1 1 1 0 HAP1 N-terminal conserved region ZapB PF06005.12 KFM82427.1 - 8.1 7.0 45.9 7.1 7.1 9.6 3.8 1 1 1 3 3 3 0 Cell division protein ZapB CENP-H PF05837.12 KFM82427.1 - 8.2 6.9 38.6 3.3 8.1 12.3 3.3 1 1 3 4 4 4 0 Centromere protein H (CENP-H) BLOC1_2 PF10046.9 KFM82427.1 - 8.7 6.7 32.1 5.4 7.4 9.2 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.15 KFM82427.1 - 9.6 6.4 33.7 3.1 8.0 1.6 5.4 1 1 5 7 7 7 0 Basic region leucine zipper PKcGMP_CC PF16808.5 KFM82428.1 - 0.033 14.1 0.2 0.045 13.6 0.2 1.2 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PI3Ka PF00613.20 KFM82429.1 - 7.1e-51 172.2 1.4 1.1e-50 171.6 1.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 KFM82429.1 - 1e-42 145.3 0.3 2.2e-42 144.3 0.1 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 JUPITER PF17054.5 KFM82431.1 - 7.8e-06 25.6 6.8 0.0006 19.4 0.2 3.2 1 1 2 3 3 3 3 Microtubule-Associated protein Jupiter PhyH PF05721.13 KFM82433.1 - 5.3e-53 180.4 0.0 6.2e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) S1 PF00575.23 KFM82434.1 - 2e-19 69.7 0.0 3.8e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 KFM82434.1 - 2.7e-14 53.3 0.0 4.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 KFM82434.1 - 2.2e-05 24.7 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Ribosomal_L20 PF00453.18 KFM82436.1 - 1.1e-09 38.4 1.2 1.3e-09 38.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 DUF4796 PF16044.5 KFM82436.1 - 0.038 13.6 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Atg8 PF02991.16 KFM82437.1 - 8.1e-49 164.1 0.0 9.5e-49 163.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFM82437.1 - 2.6e-08 34.2 0.0 3.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 LIM PF00412.22 KFM82438.1 - 1.4e-33 114.8 36.4 1.3e-12 47.7 6.0 3.2 3 0 0 3 3 3 3 LIM domain SAM_1 PF00536.30 KFM82439.1 - 1.1e-13 51.4 0.0 2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM82439.1 - 6.6e-12 45.4 0.0 1.4e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pkinase PF00069.25 KFM82440.1 - 1.3e-64 218.1 0.0 1.9e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM82440.1 - 5.3e-36 124.2 0.0 8e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFM82440.1 - 2.4e-33 113.8 27.1 1.1e-16 60.5 7.6 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KFM82440.1 - 2e-15 56.9 0.0 4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 KFM82440.1 - 8e-11 42.5 0.6 1.7e-10 41.4 0.6 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 KFM82440.1 - 0.00037 20.7 17.2 0.03 14.7 4.1 2.6 2 0 0 2 2 2 2 C1 domain Kinase-like PF14531.6 KFM82440.1 - 0.017 14.5 0.0 0.06 12.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KFM82440.1 - 0.02 14.8 0.1 0.13 12.2 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM82440.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFM82440.1 - 0.062 12.2 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain PHD PF00628.29 KFM82440.1 - 0.49 10.3 22.1 0.81 9.6 5.4 2.6 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 KFM82440.1 - 0.52 10.5 12.7 1.4 9.1 5.0 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_9 PF13901.6 KFM82440.1 - 1.4 8.8 19.1 1.7 8.6 4.4 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DZR PF12773.7 KFM82440.1 - 4.4 7.4 18.4 0.96 9.5 5.3 2.6 2 0 0 2 2 2 0 Double zinc ribbon Peptidase_S24 PF00717.23 KFM82441.1 - 1.9e-10 40.6 0.2 3e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 Peptidase S24-like CDC48_2 PF02933.17 KFM82441.1 - 0.2 11.5 0.6 13 5.7 0.1 2.6 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 MG1 PF17790.1 KFM82442.1 - 1.3e-18 67.3 0.0 2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Macroglobulin domain MG1 MG2 PF01835.19 KFM82442.1 - 0.0015 19.0 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 MG2 domain Epimerase PF01370.21 KFM82444.1 - 1.3e-57 195.1 0.0 1.7e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM82444.1 - 2.5e-13 50.1 0.4 2.6e-12 46.8 0.0 2.0 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFM82444.1 - 1.6e-06 27.5 0.9 0.00024 20.3 0.0 2.6 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFM82444.1 - 1.5e-05 24.3 0.0 4.8e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFM82444.1 - 7.4e-05 21.9 0.2 0.00085 18.4 0.2 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RepL PF05732.11 KFM82444.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Semialdhyde_dh PF01118.24 KFM82444.1 - 0.11 13.0 0.1 0.62 10.5 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CBM_14 PF01607.24 KFM82445.1 - 5.1e-09 36.2 6.1 8.4e-09 35.5 6.1 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain zf-C2H2_4 PF13894.6 KFM82447.1 - 0.053 14.4 1.4 0.053 14.4 1.4 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM82447.1 - 0.06 13.8 2.3 0.06 13.8 2.3 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2256 PF10013.9 KFM82447.1 - 1.1 9.5 4.7 0.49 10.6 0.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) PH_RBD PF12068.8 KFM82449.1 - 5.5e-16 58.5 0.1 6.7e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 Rab-binding domain (RBD) RabGAP-TBC PF00566.18 KFM82450.1 - 3.5e-48 164.1 8.5 5.1e-48 163.6 8.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF5020 PF16412.5 KFM82450.1 - 0.1 12.4 1.5 0.79 9.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5020) An_peroxidase PF03098.15 KFM82451.1 - 1.7e-121 406.4 0.0 2e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Ank_4 PF13637.6 KFM82452.1 - 4.7e-18 65.3 3.1 1e-09 38.7 0.1 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM82452.1 - 6.3e-17 61.9 0.1 1.5e-10 41.5 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFM82452.1 - 1.7e-15 56.6 2.6 2.8e-06 27.5 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat PUFD PF16553.5 KFM82452.1 - 2.9e-15 56.4 0.0 8e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 BCORL-PCGF1-binding domain Ank_5 PF13857.6 KFM82452.1 - 1.7e-14 53.7 1.4 1.2e-06 28.6 0.2 4.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM82452.1 - 2.3e-14 52.1 0.2 1.3e-06 28.3 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeat DUF3619 PF12279.8 KFM82452.1 - 0.025 14.9 1.5 0.071 13.4 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Integrase_H2C2 PF17921.1 KFM82453.1 - 8.4e-14 51.4 0.2 1.6e-13 50.6 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFM82453.1 - 0.00044 20.4 0.7 0.0022 18.2 0.1 2.4 3 0 0 3 3 3 1 H2C2 zinc finger DUF3116 PF11313.8 KFM82453.1 - 0.09 12.6 0.1 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3116) Helicase_C PF00271.31 KFM82454.1 - 2.4e-25 89.0 1.2 1.3e-24 86.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM82454.1 - 2.5e-19 69.7 0.0 7.6e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KFM82454.1 - 5e-15 55.5 0.1 1.1e-14 54.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_11 PF13086.6 KFM82454.1 - 0.017 14.9 0.9 0.76 9.5 1.4 2.4 2 0 0 2 2 2 0 AAA domain Ribosomal_L32p PF01783.23 KFM82454.1 - 0.24 11.7 2.5 0.31 11.3 0.3 2.2 2 0 0 2 2 2 0 Ribosomal L32p protein family ANF_receptor PF01094.28 KFM82455.1 - 3.5e-06 26.4 0.0 3.6e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFM82456.1 - 2.1e-34 119.3 12.1 2.4e-34 119.1 12.1 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF3278 PF11683.8 KFM82456.1 - 0.14 12.3 12.0 1.9 8.6 3.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3278) Ycf70 PF17382.2 KFM82456.1 - 0.34 11.4 0.1 0.34 11.4 0.1 2.0 2 1 1 3 3 3 0 Uncharacterized Ycf70-like RVT_1 PF00078.27 KFM82457.1 - 2.6e-05 23.9 0.1 2.6e-05 23.9 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EMP70 PF02990.16 KFM82458.1 - 1.7e-193 644.1 18.5 1.7e-193 644.1 18.5 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 Neur_chan_memb PF02932.16 KFM82459.1 - 5.5e-28 98.6 10.3 1.8e-23 83.8 5.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Acyl_transf_3 PF01757.22 KFM82460.1 - 3.4e-27 95.4 31.3 3.4e-27 95.4 31.3 1.5 2 0 0 2 2 2 1 Acyltransferase family DUF3054 PF11255.8 KFM82460.1 - 0.11 13.1 1.0 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) Aquarius_N PF16399.5 KFM82461.1 - 0 1017.8 3.3 0 1017.4 3.3 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KFM82461.1 - 1.5e-26 93.3 0.0 1.1e-25 90.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFM82461.1 - 2.5e-26 93.1 0.0 3.7e-25 89.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM82461.1 - 2.9e-08 34.2 0.0 1.4e-07 31.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KFM82461.1 - 7.5e-06 26.1 0.0 2.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFM82461.1 - 1.9e-05 24.4 0.0 0.0063 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFM82461.1 - 0.00099 19.5 0.0 0.011 16.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KFM82461.1 - 0.0022 17.5 0.0 0.0055 16.3 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KFM82461.1 - 0.0042 16.4 0.4 0.043 13.0 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KFM82461.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_18 PF13238.6 KFM82461.1 - 0.012 16.1 0.1 2.3 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 KFM82461.1 - 0.012 15.4 0.2 0.025 14.4 0.2 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Parvo_NS1 PF01057.17 KFM82461.1 - 0.02 14.0 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 KFM82461.1 - 0.037 14.3 1.0 0.4 10.9 0.1 2.8 2 1 1 3 3 2 0 AAA domain PhoH PF02562.16 KFM82461.1 - 0.041 13.3 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 KFM82461.1 - 0.079 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DnaB_C PF03796.15 KFM82461.1 - 0.081 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF4088 PF13317.6 KFM82461.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) RecA PF00154.21 KFM82461.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein RuvB_N PF05496.12 KFM82461.1 - 0.12 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain HTH_48 PF17906.1 KFM82462.1 - 1.9e-05 24.7 0.1 2.1e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase IBR PF01485.21 KFM82463.1 - 1.7e-16 60.2 51.0 7.1e-11 42.2 12.3 4.8 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KFM82463.1 - 1.2e-05 25.0 2.8 1.2e-05 25.0 2.8 5.1 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM82463.1 - 0.00058 20.1 4.3 0.00058 20.1 4.3 5.2 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KFM82463.1 - 0.0017 18.3 4.6 0.0017 18.3 4.6 4.5 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM82463.1 - 0.0033 17.2 3.9 0.0033 17.2 3.9 5.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFM82463.1 - 0.006 16.7 5.4 0.006 16.7 5.4 5.0 5 1 1 6 6 6 2 zinc finger of C3HC4-type, RING G-patch PF01585.23 KFM82464.1 - 1.1e-11 44.4 4.2 3.7e-11 42.7 4.2 2.0 1 1 0 1 1 1 1 G-patch domain Surp PF01805.20 KFM82464.1 - 1.6e-05 24.8 0.0 4.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Surp module G-patch_2 PF12656.7 KFM82464.1 - 0.00012 22.0 2.5 0.00022 21.3 0.2 2.6 2 0 0 2 2 2 1 G-patch domain DUF5446 PF17522.2 KFM82465.1 - 0.12 12.5 1.6 3.8 7.7 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5446) Peptidase_M3 PF01432.20 KFM82466.1 - 7.1e-133 444.2 1.1 8e-133 444.0 1.1 1.0 1 0 0 1 1 1 1 Peptidase family M3 DUF2418 PF10332.9 KFM82466.1 - 0.016 15.7 0.0 0.05 14.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) Nup35_RRM_2 PF14605.6 KFM82466.1 - 0.063 13.3 1.1 0.15 12.0 0.2 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Peptidase_M50B PF13398.6 KFM82466.1 - 0.25 10.9 0.3 0.37 10.4 0.3 1.3 1 0 0 1 1 1 0 Peptidase M50B-like zf-CCCH PF00642.24 KFM82468.1 - 2.7e-05 24.0 6.4 5e-05 23.1 6.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-U1 PF06220.12 KFM82468.1 - 0.00029 20.5 5.9 0.00029 20.5 5.9 2.3 2 0 0 2 2 2 1 U1 zinc finger zf_CCCH_4 PF18345.1 KFM82468.1 - 0.0053 16.8 8.7 0.0089 16.1 8.7 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KFM82468.1 - 0.015 16.0 2.1 0.023 15.4 2.1 1.3 1 0 0 1 1 1 0 Torus domain zf-CCCH_4 PF18044.1 KFM82468.1 - 0.038 13.8 7.1 0.066 13.0 7.1 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-C2H2_4 PF13894.6 KFM82468.1 - 0.081 13.8 0.2 0.081 13.8 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger INTS5_C PF14838.6 KFM82468.1 - 0.23 10.0 0.1 0.33 9.5 0.1 1.1 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus zf-CCCH_2 PF14608.6 KFM82468.1 - 0.82 10.2 5.4 1.6 9.3 5.4 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CLIP1_ZNF PF16641.5 KFM82468.1 - 3 7.8 7.7 5.9 6.9 7.7 1.5 1 0 0 1 1 1 0 CLIP1 zinc knuckle Smoothelin PF12510.8 KFM82469.1 - 3.2e-08 33.5 8.6 3.2e-08 33.5 8.6 3.1 3 0 0 3 3 3 1 Smoothelin cytoskeleton protein MotA_ExbB PF01618.16 KFM82469.1 - 0.2 11.4 1.7 10 5.9 0.4 2.9 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family CDC45 PF02724.14 KFM82469.1 - 6.4 4.9 13.0 7.8 4.6 13.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RhoGEF PF00621.20 KFM82470.1 - 1.3e-33 116.7 1.3 3.3e-33 115.4 1.3 1.7 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 KFM82470.1 - 9.2e-12 44.4 0.1 3.4e-11 42.6 0.1 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM82470.1 - 1.7e-11 43.8 0.0 4.1e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM82470.1 - 8.6e-10 38.2 0.1 8.4e-09 35.0 0.0 2.6 2 1 0 2 2 2 1 Variant SH3 domain Sec23_helical PF04815.15 KFM82470.1 - 0.065 13.1 0.2 0.36 10.7 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Rer1 PF03248.13 KFM82471.1 - 6.5e-73 244.1 9.4 7.6e-73 243.9 9.4 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 KFM82471.1 - 0.044 13.4 0.3 0.044 13.4 0.3 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF4131 PF13567.6 KFM82471.1 - 0.18 11.5 4.4 0.61 9.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ELO PF01151.18 KFM82472.1 - 0.0023 17.5 0.1 0.0029 17.2 0.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family C4 PF01413.19 KFM82473.1 - 2.3e-73 243.7 1.4 1.9e-41 140.9 0.0 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Integrase_H2C2 PF17921.1 KFM82473.1 - 0.061 13.4 0.9 2.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Integrase zinc binding domain RecR PF02132.15 KFM82473.1 - 0.45 10.1 3.6 4.3 7.0 0.3 2.6 2 0 0 2 2 2 0 RecR protein Collagen PF01391.18 KFM82474.1 - 4.7e-136 442.6 480.5 3.3e-09 36.4 22.8 19.8 3 3 12 15 15 15 13 Collagen triple helix repeat (20 copies) VRR_NUC PF08774.11 KFM82475.1 - 9.8e-24 83.5 0.0 1.9e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain TPR_2 PF07719.17 KFM82475.1 - 0.076 13.2 1.1 17 5.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ldl_recept_b PF00058.17 KFM82476.1 - 2.6e-37 127.0 4.1 1.5e-10 41.4 0.0 4.9 5 0 0 5 5 5 4 Low-density lipoprotein receptor repeat class B SGL PF08450.12 KFM82476.1 - 2.3e-07 30.6 2.8 0.0066 16.1 0.2 3.0 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 KFM82476.1 - 0.00071 18.9 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) Arylesterase PF01731.20 KFM82476.1 - 0.0056 16.9 0.0 1.2 9.4 0.0 2.6 2 1 1 3 3 3 1 Arylesterase NTNH_C PF08470.10 KFM82476.1 - 0.0066 16.3 0.0 0.071 13.0 0.0 2.5 1 1 1 2 2 2 1 Nontoxic nonhaemagglutinin C-terminal SL4P PF17618.2 KFM82476.1 - 0.19 11.8 3.1 3.2 7.9 0.0 3.2 4 0 0 4 4 4 0 Uncharacterized Strongylid L4 protein FXa_inhibition PF14670.6 KFM82477.1 - 8e-13 48.4 7.8 1.1e-12 48.0 7.8 1.2 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFM82477.1 - 3.1e-05 24.2 3.4 3.5e-05 24.0 1.6 1.8 1 1 1 2 2 2 1 EGF-like domain cEGF PF12662.7 KFM82477.1 - 0.0005 19.9 2.2 0.00086 19.2 2.2 1.4 1 0 0 1 1 1 1 Complement Clr-like EGF-like Ldl_recept_b PF00058.17 KFM82477.1 - 0.16 12.5 1.0 0.5 10.9 0.0 2.1 2 0 0 2 2 2 0 Low-density lipoprotein receptor repeat class B Phospholip_A2_2 PF05826.12 KFM82478.1 - 1.1e-36 124.9 3.4 1.1e-36 124.9 3.4 1.9 2 0 0 2 2 2 1 Phospholipase A2 PLA2G12 PF06951.11 KFM82478.1 - 0.44 10.4 9.2 3.5 7.5 9.0 2.3 1 1 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_1 PF00068.19 KFM82478.1 - 3.2 8.3 18.1 0.63 10.5 3.0 3.1 2 1 1 3 3 3 0 Phospholipase A2 Phospholip_A2_2 PF05826.12 KFM82479.1 - 2.2e-33 114.3 4.9 3.6e-33 113.7 4.9 1.3 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 KFM82479.1 - 0.11 13.0 12.9 3.6 8.1 12.9 2.5 1 1 0 1 1 1 0 Phospholipase A2 Transposase_1 PF01359.18 KFM82480.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Transposase (partial DDE domain) Phospholip_A2_2 PF05826.12 KFM82481.1 - 1.5e-35 121.3 3.7 3.9e-35 120.0 3.7 1.7 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 KFM82481.1 - 0.056 13.9 11.0 0.3 11.6 4.7 2.6 1 1 1 2 2 2 0 Phospholipase A2 NTF-like PF14540.6 KFM82481.1 - 0.16 11.7 0.1 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 Nucleotidyltransferase-like Phospholip_A2_2 PF05826.12 KFM82482.1 - 6.3e-17 61.6 0.6 1.5e-16 60.4 0.6 1.7 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 KFM82483.1 - 9.9e-37 125.1 4.4 2.1e-36 124.0 4.4 1.6 1 0 0 1 1 1 1 Phospholipase A2 TetR_C_19 PF17924.1 KFM82483.1 - 0.14 12.8 0.0 0.46 11.1 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Phospholip_A2_1 PF00068.19 KFM82483.1 - 2.8 8.5 19.5 9.7 6.7 12.1 3.1 2 1 0 2 2 2 0 Phospholipase A2 MFS_1 PF07690.16 KFM82484.1 - 0.0087 15.0 9.5 0.014 14.4 9.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFM82485.1 - 8.8e-13 47.9 9.4 4e-12 45.7 6.7 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFM82485.1 - 2e-08 33.0 0.6 4.4e-05 22.0 0.0 2.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family EPOP PF15223.6 KFM82485.1 - 0.058 12.8 3.7 0.072 12.5 3.7 1.1 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein Kelch_1 PF01344.25 KFM82486.1 - 2.2e-86 283.2 20.5 9.7e-16 57.1 0.7 6.5 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFM82486.1 - 2.9e-40 135.3 2.7 2.3e-06 27.7 0.1 6.3 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFM82486.1 - 6.9e-37 125.7 1.9 9.5e-37 125.2 1.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFM82486.1 - 1.8e-30 105.4 0.4 3.8e-30 104.4 0.4 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KFM82486.1 - 3.1e-27 94.3 9.8 3e-05 24.2 0.2 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFM82486.1 - 1.4e-25 88.3 5.4 5e-06 26.3 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFM82486.1 - 3.9e-23 81.2 1.1 0.0027 17.7 0.0 6.2 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM82486.1 - 4.3e-06 26.6 7.7 2.6 8.1 0.1 5.3 5 0 0 5 5 5 3 Kelch motif PQQ_3 PF13570.6 KFM82486.1 - 0.0035 17.8 6.8 8.3 7.0 0.0 4.9 5 0 0 5 5 5 1 PQQ-like domain DUF3342 PF11822.8 KFM82486.1 - 0.017 15.3 0.1 0.28 11.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) S_layer_N PF05123.12 KFM82486.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 S-layer like family, N-terminal region Beta_helix_2 PF18835.1 KFM82488.1 - 0.057 13.2 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase PDZ PF00595.24 KFM82489.1 - 3.6e-12 46.5 0.0 4.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM82489.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM82489.1 - 3.2e-07 30.6 0.0 4.3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain BCDHK_Adom3 PF10436.9 KFM82490.1 - 1.5e-40 138.6 0.0 2.6e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFM82490.1 - 2.3e-15 57.1 0.0 2e-14 54.0 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFM82490.1 - 0.0099 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Imm71 PF15602.6 KFM82490.1 - 0.19 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 71 Cadherin PF00028.17 KFM82491.1 - 1.2e-96 317.4 15.1 1.8e-13 50.8 0.0 9.3 9 0 0 9 9 9 9 Cadherin domain Cadherin_3 PF16184.5 KFM82491.1 - 2.9e-09 36.9 20.9 0.025 14.6 0.0 7.8 9 0 0 9 9 9 5 Cadherin-like Cadherin_4 PF17803.1 KFM82491.1 - 0.0002 21.9 38.8 0.19 12.3 0.1 8.4 9 1 0 9 9 9 3 Bacterial cadherin-like domain Cadherin_2 PF08266.12 KFM82491.1 - 0.0016 18.2 0.0 8.4 6.3 0.0 5.1 5 0 0 5 5 5 1 Cadherin-like Big_9 PF17963.1 KFM82491.1 - 0.011 16.4 30.4 1.6 9.5 0.6 7.1 7 1 0 7 7 7 0 Bacterial Ig domain SNF PF00209.18 KFM82492.1 - 1.3e-108 364.0 19.4 4.2e-84 283.1 9.3 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family DUF1304 PF06993.12 KFM82492.1 - 0.031 14.3 1.2 0.031 14.3 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) Ofd1_CTDD PF10637.9 KFM82494.1 - 9.2e-21 74.3 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KFM82494.1 - 0.00094 19.8 0.1 0.0014 19.3 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KFM82495.1 - 0.0043 17.7 0.2 0.011 16.3 0.2 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KFM82497.1 - 2e-42 145.4 0.0 2.2e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM82497.1 - 6.6e-25 87.9 0.0 7.3e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM82497.1 - 2.1e-06 27.2 0.0 2.8e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM82497.1 - 1.2e-05 25.4 0.0 0.0023 17.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFM82497.1 - 0.00048 19.2 0.0 0.00054 19.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM82497.1 - 0.00063 19.2 0.0 0.00081 18.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFM82497.1 - 0.0016 18.1 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFM82497.1 - 0.0024 17.5 0.0 0.004 16.8 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Act-Frag_cataly PF09192.10 KFM82497.1 - 0.035 13.5 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic YcxB PF14317.6 KFM82497.1 - 0.054 13.2 0.9 0.08 12.7 0.9 1.3 1 0 0 1 1 1 0 YcxB-like protein Pkinase PF00069.25 KFM82498.1 - 7e-07 28.9 0.0 9.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain KA1 PF02149.19 KFM82499.1 - 1.2e-12 47.4 1.1 1.5e-12 47.1 0.2 1.6 2 0 0 2 2 2 1 Kinase associated domain 1 Ski_Sno PF02437.17 KFM82500.1 - 3e-37 126.7 0.0 4.7e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 SKI/SNO/DAC family NOA36 PF06524.12 KFM82501.1 - 2.1 7.6 10.7 3.6 6.8 10.7 1.4 1 0 0 1 1 1 0 NOA36 protein Macoilin PF09726.9 KFM82501.1 - 6.7 5.1 23.7 19 3.6 23.7 1.9 1 1 0 1 1 1 0 Macoilin family Toxin_TOLIP PF00087.21 KFM82503.1 - 1.9 8.8 5.6 3.1 8.1 0.1 3.4 2 1 2 4 4 4 0 Snake toxin and toxin-like protein Xpo1 PF08389.12 KFM82504.1 - 1.5e-12 47.8 0.1 2.5e-12 47.1 0.1 1.4 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KFM82504.1 - 0.016 15.1 0.1 6.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Importin-beta N-terminal domain Bcl-2 PF00452.19 KFM82505.1 - 9.4e-05 23.0 0.2 0.0036 17.9 0.0 3.1 3 0 0 3 3 3 1 Apoptosis regulator proteins, Bcl-2 family Xpo1 PF08389.12 KFM82505.1 - 0.0033 17.5 0.4 0.68 10.0 0.0 3.0 2 0 0 2 2 2 2 Exportin 1-like protein IFRD PF05004.13 KFM82505.1 - 0.067 12.3 0.0 0.29 10.2 0.0 2.0 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KFM82505.1 - 0.27 11.3 1.5 17 5.6 0.1 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RP-C_C PF11800.8 KFM82507.1 - 0.12 12.4 4.0 0.21 11.7 4.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Pkinase PF00069.25 KFM82508.1 - 2e-137 456.8 0.0 1.6e-67 227.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM82508.1 - 1.4e-70 237.5 0.0 1.3e-38 132.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFM82508.1 - 1.2e-14 54.3 0.0 4.1e-07 29.6 0.0 3.4 3 1 0 4 4 4 2 Kinase-like Pkinase_fungal PF17667.1 KFM82508.1 - 5.5e-09 35.3 0.0 0.00024 20.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 KFM82508.1 - 3.1e-08 33.2 0.0 0.0095 15.3 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM82508.1 - 1.9e-05 24.7 0.0 0.25 11.2 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFM82508.1 - 4e-05 23.2 0.0 0.046 13.2 0.0 2.6 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFM82508.1 - 0.00064 19.4 0.1 0.17 11.4 0.0 2.7 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 KFM82508.1 - 0.0023 17.6 0.2 14 5.3 0.0 3.7 4 0 0 4 4 4 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFM82508.1 - 0.019 13.9 0.2 0.06 12.3 0.1 1.8 2 0 0 2 2 2 0 Haspin like kinase domain DUF3402 PF11882.8 KFM82509.1 - 6.7e-96 322.2 13.1 1.4e-64 218.9 3.4 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) Importin_rep_6 PF18829.1 KFM82509.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Importin repeat 6 N1221 PF07923.13 KFM82510.1 - 5.2e-31 107.9 0.0 7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 N1221-like protein DUF3402 PF11882.8 KFM82510.1 - 0.091 11.8 0.3 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) DNA_pol_B_2 PF03175.13 KFM82511.1 - 0.00014 20.8 0.1 0.00019 20.5 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Tetraspanin PF00335.20 KFM82512.1 - 2.6e-43 148.4 10.1 3e-43 148.2 10.1 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KFM82512.1 - 0.057 13.2 9.5 0.079 12.7 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Wzy_C PF04932.15 KFM82512.1 - 0.45 10.1 3.8 6.2 6.4 3.8 2.3 1 1 0 1 1 1 0 O-Antigen ligase HemY_N PF07219.13 KFM82512.1 - 3.9 7.7 9.6 6 7.1 0.2 3.3 2 1 1 3 3 3 0 HemY protein N-terminus RILP PF11461.8 KFM82513.1 - 0.002 18.3 2.2 0.0097 16.1 1.2 2.8 2 0 0 2 2 2 1 Rab interacting lysosomal protein Elongin_A PF06881.11 KFM82513.1 - 4 8.0 11.2 0.11 13.0 0.9 3.0 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PDZ PF00595.24 KFM82514.1 - 5.8e-26 90.7 0.1 5.6e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM82514.1 - 4.9e-15 55.1 0.2 2.2e-08 33.8 0.2 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFM82514.1 - 1.1e-09 38.5 0.0 0.0028 17.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain DUF4358 PF14270.6 KFM82515.1 - 0.042 14.1 1.0 1.4 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) FANCI_S1-cap PF14674.6 KFM82515.1 - 0.23 11.5 1.5 1.7 8.8 0.3 2.3 2 0 0 2 2 2 0 FANCI solenoid 1 cap OAD_gamma PF04277.13 KFM82516.1 - 1.1 9.9 3.6 1.5 9.5 0.6 1.9 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Peptidase_A17 PF05380.13 KFM82517.1 - 4.5e-16 59.3 0.1 4.9e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 Pao retrotransposon peptidase zf-HC5HC2H PF13771.6 KFM82518.1 - 1.2e-09 38.3 12.6 1.2e-09 38.3 12.6 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFM82518.1 - 6.9e-09 35.9 12.7 7e-09 35.8 10.2 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain Orf78 PF06024.12 KFM82519.1 - 0.0041 17.4 0.2 0.008 16.5 0.2 1.4 1 0 0 1 1 1 1 Orf78 (ac78) Vma12 PF11712.8 KFM82519.1 - 0.0096 16.0 0.2 0.017 15.2 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase SP_C-Propep PF08999.10 KFM82519.1 - 0.01 15.6 0.1 0.027 14.3 0.1 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ASFV_J13L PF05568.11 KFM82519.1 - 0.012 15.4 0.2 0.028 14.2 0.2 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein LRRC37AB_C PF14914.6 KFM82519.1 - 0.019 14.9 0.3 0.019 14.9 0.3 1.7 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain TMEM154 PF15102.6 KFM82519.1 - 0.031 14.2 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family STE3 PF02076.15 KFM82519.1 - 0.051 12.8 0.3 0.084 12.1 0.3 1.3 1 0 0 1 1 1 0 Pheromone A receptor Stevor PF17410.2 KFM82519.1 - 0.051 13.1 1.8 0.093 12.3 1.8 1.7 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame RIFIN PF02009.16 KFM82519.1 - 0.12 12.3 0.6 0.18 11.6 0.6 1.2 1 0 0 1 1 1 0 Rifin ECSCR PF15820.5 KFM82519.1 - 0.15 11.9 0.6 0.68 9.8 0.1 2.1 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator MAP17 PF15807.5 KFM82519.1 - 0.81 9.9 3.0 5.9 7.1 0.2 3.0 2 1 1 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 zf-H2C2_2 PF13465.6 KFM82520.1 - 5.6e-07 29.7 1.6 5.6e-07 29.7 1.6 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM82520.1 - 1.7e-06 28.1 28.4 0.00023 21.4 2.1 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM82520.1 - 0.00067 20.3 23.5 0.012 16.4 1.7 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM82520.1 - 0.0082 16.5 14.9 0.35 11.3 1.1 3.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM82520.1 - 0.098 12.7 0.7 0.098 12.7 0.7 2.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM82520.1 - 0.13 12.0 0.3 0.13 12.0 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain NnrU PF07298.11 KFM82520.1 - 0.22 11.0 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 NnrU protein zf_C2H2_ZHX PF18387.1 KFM82520.1 - 0.62 9.7 4.2 0.21 11.3 0.9 1.9 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KFM82520.1 - 1.2 9.6 0.1 1.2 9.6 0.1 3.9 3 2 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.22 KFM82521.1 - 5.7e-21 74.1 0.0 8.2e-21 73.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFM82521.1 - 0.15 12.3 0.0 0.48 10.7 0.0 1.9 1 0 0 1 1 1 0 RRM-like domain RRM_occluded PF16842.5 KFM82521.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif XRN_M PF17846.1 KFM82521.1 - 1.1 8.1 3.3 1.4 7.8 3.3 1.3 1 0 0 1 1 1 0 Xrn1 helical domain GAS PF13851.6 KFM82522.1 - 2.2e-09 37.0 63.3 0.00015 21.2 14.0 4.2 3 1 1 4 4 4 4 Growth-arrest specific micro-tubule binding CC2-LZ PF16516.5 KFM82522.1 - 2.8e-09 37.3 8.9 2.8e-09 37.3 8.9 6.0 2 2 3 6 6 5 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator NEMO PF11577.8 KFM82522.1 - 5.6e-07 29.5 4.9 5.6e-07 29.5 4.9 4.9 4 3 1 5 5 4 1 NF-kappa-B essential modulator NEMO DUF1664 PF07889.12 KFM82522.1 - 0.0011 19.0 38.9 0.018 15.1 3.0 5.2 3 2 1 4 4 4 3 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 KFM82522.1 - 0.0022 18.1 9.5 0.0022 18.1 9.5 8.1 4 2 2 7 7 7 1 Centrosomin N-terminal motif 1 MscS_porin PF12795.7 KFM82522.1 - 0.0045 16.6 9.0 0.0045 16.6 9.0 4.8 3 2 0 4 4 3 2 Mechanosensitive ion channel porin domain Filament PF00038.21 KFM82522.1 - 0.017 14.7 59.1 0.48 10.0 16.3 4.3 2 2 1 4 4 4 0 Intermediate filament protein Lebercilin PF15619.6 KFM82522.1 - 0.019 14.6 69.0 0.39 10.4 16.2 4.9 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease LPP PF04728.13 KFM82522.1 - 0.21 12.0 0.1 0.21 12.0 0.1 6.1 5 0 0 5 5 5 0 Lipoprotein leucine-zipper DpnI_C PF17726.1 KFM82522.1 - 0.32 11.1 5.7 0.41 10.8 2.8 2.7 2 0 0 2 2 2 0 Dam-replacing HTH domain ATG16 PF08614.11 KFM82522.1 - 0.48 10.6 65.9 0.02 15.1 12.6 4.7 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Octopine_DH PF02317.17 KFM82522.1 - 3 7.9 11.8 0.81 9.8 2.1 3.2 2 1 0 3 3 3 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Par3_HAL_N_term PF12053.8 KFM82522.1 - 5.2 7.3 5.9 5.3 7.3 0.5 3.1 3 0 0 3 3 3 0 N-terminal of Par3 and HAL proteins Fez1 PF06818.15 KFM82522.1 - 7 7.0 66.2 0.22 11.9 10.9 3.5 1 1 1 3 3 3 0 Fez1 EGF_CA PF07645.15 KFM82523.1 - 2.8e-145 472.3 269.6 1.3e-10 41.3 6.6 20.2 19 1 1 20 20 20 18 Calcium-binding EGF domain cEGF PF12662.7 KFM82523.1 - 2.2e-84 276.9 158.0 1.2e-10 41.1 3.8 20.4 21 1 0 21 21 21 17 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFM82523.1 - 3.9e-24 84.6 239.4 6.5e-09 35.9 6.1 22.2 17 6 3 20 20 20 11 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFM82523.1 - 8.7e-17 61.0 206.0 0.00026 21.1 4.2 21.4 18 1 1 19 19 19 13 EGF domain EGF PF00008.27 KFM82523.1 - 1.5e-05 25.2 44.7 0.00057 20.1 3.7 22.1 21 3 0 21 21 21 7 EGF-like domain hEGF PF12661.7 KFM82523.1 - 0.029 15.0 1.5 0.029 15.0 1.5 25.7 25 2 1 26 26 26 0 Human growth factor-like EGF AXH PF08517.12 KFM82524.1 - 9.4e-28 97.1 0.0 1.9e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) HCV_NS5a_1b PF08301.13 KFM82524.1 - 0.015 15.8 0.0 0.042 14.4 0.0 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b PDZ_6 PF17820.1 KFM82525.1 - 3.3e-11 42.9 0.1 6.2e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM82525.1 - 2.5e-08 34.1 0.1 4e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Macoilin PF09726.9 KFM82525.1 - 1.1 7.8 6.7 1.2 7.6 6.7 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 KFM82525.1 - 2.1 7.0 5.1 2.3 6.9 5.1 1.0 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KFM82525.1 - 3.7 6.7 7.0 4.3 6.5 7.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM76 PF16046.5 KFM82525.1 - 4 6.7 10.2 5 6.4 10.2 1.1 1 0 0 1 1 1 0 FAM76 protein Na_Pi_cotrans PF02690.15 KFM82527.1 - 1.3e-19 70.7 3.5 6.5e-15 55.4 1.1 3.1 2 1 1 3 3 3 2 Na+/Pi-cotransporter HTH_Tnp_Tc5 PF03221.16 KFM82528.1 - 1.3e-20 73.2 12.0 3.9e-07 30.0 0.1 6.2 6 0 0 6 6 6 4 Tc5 transposase DNA-binding domain BrkDBD PF09607.10 KFM82528.1 - 1.8e-19 69.2 19.4 2.5e-05 24.0 0.1 5.9 5 0 0 5 5 5 5 Brinker DNA-binding domain CENP-B_N PF04218.13 KFM82528.1 - 6.3e-14 51.3 7.2 0.14 11.8 0.0 5.9 5 0 0 5 5 5 5 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 KFM82528.1 - 6.2e-08 32.7 6.8 0.037 14.2 0.0 5.7 5 0 0 5 5 5 2 Helix-turn-helix domain DDE_1 PF03184.19 KFM82528.1 - 1.8e-06 27.8 0.5 1e-05 25.3 0.0 2.6 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 KFM82528.1 - 6.7e-05 23.1 15.7 0.033 14.5 0.4 4.8 4 0 0 4 4 4 2 Transposase HTH_23 PF13384.6 KFM82528.1 - 0.00016 21.3 12.9 0.72 9.7 0.0 6.1 6 0 0 6 6 6 2 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 KFM82528.1 - 0.00046 20.2 14.1 0.17 11.9 0.5 5.2 5 0 0 5 5 5 2 Transposase HTH_17 PF12728.7 KFM82528.1 - 2.8 8.2 4.4 22 5.3 0.0 4.0 5 0 0 5 5 5 0 Helix-turn-helix domain KH_1 PF00013.29 KFM82530.1 - 0.037 13.8 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 KH domain Peptidase_C1_2 PF03051.15 KFM82530.1 - 0.21 10.4 0.0 0.23 10.2 0.0 1.0 1 0 0 1 1 1 0 Peptidase C1-like family KH_1 PF00013.29 KFM82531.1 - 9.1e-19 67.1 1.4 1.1e-18 66.8 1.4 1.1 1 0 0 1 1 1 1 KH domain MOEP19 PF16005.5 KFM82531.1 - 6.5e-05 22.9 0.0 7.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 KH-like RNA-binding domain KH_2 PF07650.17 KFM82531.1 - 0.00053 19.8 0.2 0.00058 19.6 0.2 1.3 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KFM82531.1 - 0.083 12.8 2.2 0.15 12.0 0.8 2.0 2 1 0 2 2 2 0 KH domain EF-hand_7 PF13499.6 KFM82532.1 - 1.6e-08 34.9 6.1 0.001 19.5 1.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFM82532.1 - 5.5e-07 28.7 3.5 0.25 11.0 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFM82532.1 - 2.3e-06 27.1 7.1 0.009 15.9 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFM82532.1 - 0.054 13.0 1.6 1.9 8.1 0.0 3.2 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 KFM82532.1 - 0.97 9.3 3.9 1.3 8.9 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain pair UAA PF08449.11 KFM82533.1 - 8.9e-54 182.7 17.0 1.1e-53 182.4 17.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFM82533.1 - 2.1e-13 50.6 20.4 4.2e-07 30.2 10.6 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KFM82533.1 - 7.9e-09 35.3 13.1 8.1e-08 31.9 13.1 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 KFM82533.1 - 0.0017 17.9 9.3 0.0017 17.9 9.3 1.3 1 1 0 1 1 1 1 Solute carrier family 35 Pex24p PF06398.11 KFM82533.1 - 0.024 13.7 0.8 0.045 12.7 0.8 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin TMEM234 PF10639.9 KFM82533.1 - 0.085 12.9 5.5 1.3 9.1 0.6 2.7 2 1 0 2 2 2 0 Putative transmembrane family 234 AtpR PF12966.7 KFM82533.1 - 2.3 8.7 7.4 0.52 10.8 0.2 3.4 2 1 2 4 4 4 0 N-ATPase, AtpR subunit DcpS_C PF11969.8 KFM82534.1 - 0.03 14.8 0.1 0.037 14.5 0.1 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Kinesin PF00225.23 KFM82535.1 - 2.2e-96 322.7 0.6 3.8e-96 321.9 0.6 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM82535.1 - 3.6e-16 59.4 0.1 1e-15 57.9 0.1 1.8 1 0 0 1 1 1 1 Microtubule binding PolyA_pol PF01743.20 KFM82535.1 - 0.26 11.7 1.3 8.6 6.8 0.1 3.1 3 0 0 3 3 3 0 Poly A polymerase head domain Sbi-IV PF11621.8 KFM82535.1 - 0.39 11.1 4.9 20 5.6 0.1 3.7 4 1 0 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI STN1_2 PF09170.10 KFM82535.1 - 6 7.1 7.8 3.5 7.8 0.1 3.0 4 0 0 4 4 4 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 PIG-P PF08510.12 KFM82537.1 - 5.1e-37 126.5 6.2 5.9e-37 126.3 6.2 1.0 1 0 0 1 1 1 1 PIG-P DUF5084 PF16894.5 KFM82537.1 - 0.0038 17.7 3.3 0.0061 17.0 3.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5084) DPM2 PF07297.12 KFM82537.1 - 0.027 14.8 7.9 0.04 14.2 7.9 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Arf PF00025.21 KFM82538.1 - 1.3e-35 122.4 0.3 1.4e-35 122.3 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFM82538.1 - 7e-10 39.2 0.3 8e-10 39.0 0.3 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM82538.1 - 8.4e-07 28.7 0.1 9.4e-07 28.6 0.1 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFM82538.1 - 1.1e-05 24.8 0.4 2.1e-05 23.9 0.4 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KFM82538.1 - 0.00045 19.6 0.1 0.00049 19.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM82538.1 - 0.0089 15.6 0.0 0.0099 15.4 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM82538.1 - 0.031 14.4 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase EF-hand_6 PF13405.6 KFM82540.1 - 3.3e-07 29.7 0.5 3.3e-07 29.7 0.5 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KFM82540.1 - 5.5e-07 28.7 0.6 5.5e-07 28.7 0.6 3.1 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 KFM82540.1 - 6.9e-07 29.6 0.8 1.6e-06 28.4 0.8 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM82540.1 - 2.6e-05 23.5 0.6 2.6e-05 23.5 0.6 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFM82540.1 - 0.044 13.6 1.5 0.15 11.9 0.1 2.3 2 1 0 2 2 2 0 EF-hand domain pair DUF3741 PF12552.8 KFM82540.1 - 0.076 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) HrpJ PF07201.11 KFM82540.1 - 0.14 12.4 0.1 0.43 10.9 0.3 1.6 2 0 0 2 2 2 0 HrpJ-like domain S_tail_recep_bd PF14928.6 KFM82541.1 - 7.4 7.3 7.7 3.6 8.3 0.2 2.8 1 1 1 2 2 2 0 Short tail fibre protein receptor-binding domain Methyltransf_15 PF09445.10 KFM82542.1 - 1.2e-42 145.4 0.1 1.6e-42 144.9 0.1 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KFM82542.1 - 1.7e-09 37.7 0.0 2.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM82542.1 - 1.5e-08 35.3 0.0 2.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KFM82542.1 - 3.4e-07 30.2 0.2 1.7e-06 27.9 0.2 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 KFM82542.1 - 4.7e-07 29.7 0.1 9.4e-07 28.8 0.1 1.4 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 KFM82542.1 - 2.1e-05 25.1 0.0 3.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM82542.1 - 2.4e-05 24.1 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 KFM82542.1 - 4.5e-05 23.1 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KFM82542.1 - 0.00022 21.2 0.1 0.00042 20.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KFM82542.1 - 0.0051 16.0 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase UDPG_MGDP_dh_N PF03721.14 KFM82542.1 - 0.0076 15.8 0.1 0.015 14.9 0.1 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PrmA PF06325.13 KFM82542.1 - 0.013 14.9 0.1 0.019 14.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_5 PF01795.19 KFM82542.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family Methyltransf_8 PF05148.15 KFM82542.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase MethyltransfD12 PF02086.15 KFM82542.1 - 0.018 14.7 0.3 0.037 13.7 0.2 1.5 1 1 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.16 KFM82542.1 - 0.023 13.9 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase N6_N4_Mtase PF01555.18 KFM82542.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 DNA methylase tRNA_U5-meth_tr PF05958.11 KFM82542.1 - 0.055 12.5 0.1 0.083 11.9 0.1 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase ADH_zinc_N PF00107.26 KFM82542.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 KFM82542.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 KFM82542.1 - 0.12 12.0 0.1 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 KFM82542.1 - 0.15 13.1 0.0 0.23 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NDK PF00334.19 KFM82543.1 - 3.3e-13 49.8 0.1 3.6e-13 49.7 0.1 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MR_MLE_C PF13378.6 KFM82545.1 - 2.6e-60 203.7 0.0 3.8e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KFM82545.1 - 5.4e-09 36.3 0.0 9.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KFM82545.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus FMO-like PF00743.19 KFM82546.1 - 2.3e-15 56.0 0.6 1.7e-08 33.4 0.2 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like DUF4839 PF16127.5 KFM82546.1 - 0.055 13.6 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4839) FMO-like PF00743.19 KFM82547.1 - 1.4e-154 515.5 0.1 1.6e-154 515.3 0.1 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM82547.1 - 4e-19 69.0 0.8 1.9e-13 50.3 0.4 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM82547.1 - 1e-12 47.9 0.0 2.2e-10 40.2 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM82547.1 - 7.4e-12 45.1 1.5 8.7e-08 31.7 0.1 4.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFM82547.1 - 1.1e-05 25.9 0.9 0.24 12.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM82547.1 - 1.6e-05 25.0 0.2 0.00017 21.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFM82547.1 - 4.5e-05 22.8 0.1 0.058 12.6 0.0 2.7 3 0 0 3 3 3 2 Thi4 family IlvN PF07991.12 KFM82547.1 - 0.0039 16.8 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_2 PF00890.24 KFM82547.1 - 0.011 14.8 0.5 1.8 7.5 0.3 2.4 2 1 0 2 2 2 0 FAD binding domain DAO PF01266.24 KFM82547.1 - 0.029 14.0 0.1 12 5.4 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KFM82547.1 - 0.079 13.0 0.0 8.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFM82547.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM82547.1 - 0.15 11.4 0.1 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_5 PF13857.6 KFM82548.1 - 5.3e-26 90.3 4.1 2.7e-13 49.8 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM82548.1 - 1.3e-20 72.9 0.8 4.7e-07 30.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KFM82548.1 - 1.5e-19 70.3 1.5 9.2e-10 39.0 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM82548.1 - 5.7e-17 60.1 0.2 8.9e-05 22.6 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFM82548.1 - 2.4e-12 47.1 0.6 9.7e-09 35.6 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 KFM82548.1 - 3.5e-08 33.8 0.1 6.8e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM82548.1 - 9.4e-08 32.1 0.1 2.3e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NPV_P10 PF05531.12 KFM82548.1 - 0.023 15.1 1.5 0.023 15.1 1.5 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.25 KFM82549.1 - 2e-65 220.8 1.1 4e-65 219.8 1.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM82549.1 - 8.6e-50 169.4 0.4 1.8e-49 168.4 0.4 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM82549.1 - 1.4e-05 24.0 0.0 1.4e-05 24.0 0.0 2.4 3 1 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 KFM82549.1 - 0.007 15.7 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFM82549.1 - 0.017 15.1 0.0 4.4 7.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM82549.1 - 0.048 13.0 0.3 0.098 12.0 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFM82549.1 - 0.58 9.8 5.4 7.8 6.1 0.1 3.3 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Lipase PF00151.19 KFM82550.1 - 0.0024 17.2 2.2 0.0027 17.1 2.2 1.0 1 0 0 1 1 1 1 Lipase Lipase PF00151.19 KFM82551.1 - 3.8e-23 82.3 0.0 3.8e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Lipase MADF_DNA_bdg PF10545.9 KFM82554.1 - 5.3e-20 71.5 0.5 9.1e-20 70.8 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 KFM82554.1 - 5.4e-05 22.9 0.0 0.00015 21.5 0.0 1.8 1 0 0 1 1 1 1 BESS motif An_peroxidase PF03098.15 KFM82555.1 - 1e-06 27.6 0.0 1e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase ESCRT-II PF05871.12 KFM82556.1 - 2.3e-52 177.0 3.1 2.3e-52 177.0 3.1 1.4 2 0 0 2 2 2 1 ESCRT-II complex subunit PadR PF03551.14 KFM82556.1 - 0.0079 16.1 0.2 1 9.4 0.0 2.3 2 0 0 2 2 2 2 Transcriptional regulator PadR-like family ApbA_C PF08546.11 KFM82556.1 - 0.023 14.9 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.24 KFM82558.1 - 0.19 11.3 0.0 0.19 11.3 0.0 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.25 KFM82560.1 - 2.4e-43 147.9 0.0 3.5e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM82560.1 - 9.4e-27 94.1 0.0 1.4e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM82560.1 - 3.4e-12 46.7 0.0 5.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFM82560.1 - 0.0013 18.2 0.0 0.024 14.0 0.0 2.2 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) MgtE PF01769.16 KFM82560.1 - 0.016 15.6 5.3 0.041 14.3 5.3 1.7 1 0 0 1 1 1 0 Divalent cation transporter Eno-Rase_NADH_b PF12242.8 KFM82560.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TMEM214 PF10151.9 KFM82560.1 - 0.16 10.4 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Toxin_7 PF05980.12 KFM82561.1 - 0.021 15.1 3.8 0.021 15.1 3.8 1.8 2 0 0 2 2 2 0 Toxin 7 Toxin_30 PF08117.11 KFM82562.1 - 0.48 10.7 4.1 0.75 10.1 4.1 1.3 1 0 0 1 1 1 0 Ptu family DLIC PF05783.11 KFM82564.1 - 6.2e-163 543.0 0.0 1.1e-162 542.2 0.0 1.2 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) Axin_b-cat_bind PF08833.10 KFM82564.1 - 0.0038 17.3 0.4 0.43 10.7 0.1 3.0 1 1 1 2 2 2 1 Axin beta-catenin binding domain Roc PF08477.13 KFM82564.1 - 0.0064 16.7 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KFM82564.1 - 0.051 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KFM82564.1 - 0.056 13.2 0.1 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KFM82564.1 - 0.073 13.4 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFM82564.1 - 0.13 11.4 0.8 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KFM82564.1 - 0.25 11.2 1.8 5.5 6.9 0.1 2.7 3 0 0 3 3 3 0 RsgA GTPase BORCS6 PF10157.9 KFM82565.1 - 0.0056 16.9 0.0 0.0059 16.8 0.0 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Flagellar_rod PF05149.12 KFM82565.1 - 0.0073 15.8 0.0 0.0094 15.4 0.0 1.0 1 0 0 1 1 1 1 Paraflagellar rod protein PMC2NT PF08066.12 KFM82565.1 - 0.044 14.5 0.1 0.054 14.2 0.1 1.1 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DUF1664 PF07889.12 KFM82565.1 - 0.069 13.2 0.1 0.085 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CorA PF01544.18 KFM82565.1 - 0.2 10.9 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mito_carr PF00153.27 KFM82566.1 - 1.3e-49 166.0 5.9 2.3e-20 72.3 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CENP-F_leu_zip PF10473.9 KFM82567.1 - 0.00071 19.6 23.2 0.00071 19.6 23.2 4.0 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFM82567.1 - 0.003 16.5 25.6 0.003 16.5 25.6 3.0 1 1 2 3 3 3 1 Spc7 kinetochore protein DUF3584 PF12128.8 KFM82567.1 - 0.0072 13.9 35.1 0.0089 13.6 35.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PilJ PF13675.6 KFM82567.1 - 0.014 15.4 0.9 0.043 13.8 0.2 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.12 KFM82567.1 - 0.24 11.4 28.9 0.053 13.6 2.2 4.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 KFM82567.1 - 3 7.5 40.3 3.7 7.2 4.5 4.0 1 1 3 4 4 4 0 SWI5-dependent HO expression protein 3 ERM PF00769.19 KFM82567.1 - 3.2 7.5 50.0 0.011 15.6 24.1 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF812 PF05667.11 KFM82567.1 - 8 5.2 43.9 2.5 6.9 40.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) SMC_N PF02463.19 KFM82568.1 - 4.5e-34 117.8 0.3 1.2e-33 116.4 0.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFM82568.1 - 2e-25 89.3 0.0 5.6e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFM82568.1 - 7.7e-07 29.2 0.3 2.5e-06 27.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KFM82568.1 - 0.036 14.3 0.1 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit WXG100 PF06013.12 KFM82568.1 - 2.5 8.4 6.9 29 5.0 0.2 4.1 4 1 1 5 5 5 0 Proteins of 100 residues with WXG YscO PF07321.12 KFM82568.1 - 8.8 6.3 34.4 1.8 8.5 15.7 4.2 3 1 1 4 4 4 0 Type III secretion protein YscO DUF948 PF06103.11 KFM82568.1 - 9.4 6.6 13.4 1.3 9.3 0.8 4.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CRIC_ras_sig PF10534.9 KFM82569.1 - 8.9e-23 80.3 0.1 3.5e-22 78.4 0.1 2.1 1 0 0 1 1 1 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.30 KFM82569.1 - 2.4e-11 43.9 0.0 5.6e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFM82569.1 - 3.8e-10 39.5 0.0 2.9e-08 33.4 0.0 2.6 2 0 0 2 2 2 1 PDZ domain SAM_2 PF07647.17 KFM82569.1 - 1.3e-08 34.8 0.1 4.2e-08 33.2 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 KFM82569.1 - 4.9e-07 30.0 0.1 1.6e-06 28.4 0.1 1.9 1 0 0 1 1 1 1 PDZ domain SAM_PNT PF02198.16 KFM82569.1 - 0.017 15.0 0.1 0.051 13.5 0.1 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain RA PF00788.23 KFM82570.1 - 4.5e-38 129.8 1.2 5.4e-18 65.4 0.0 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 KFM82570.1 - 1.8e-35 121.3 2.1 5.2e-35 119.8 2.1 1.9 1 0 0 1 1 1 1 DIL domain PDZ PF00595.24 KFM82570.1 - 1.1e-15 57.7 1.1 3e-15 56.3 1.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFM82570.1 - 2.5e-08 33.7 0.3 7.3e-08 32.1 0.3 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM82570.1 - 0.00031 21.0 0.4 0.00085 19.6 0.4 1.7 1 0 0 1 1 1 1 PDZ domain FERM_f0 PF16511.5 KFM82570.1 - 0.059 13.7 0.5 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM SOCS_box PF07525.16 KFM82571.1 - 2.9e-10 40.3 0.9 1.1e-09 38.4 0.9 2.1 1 0 0 1 1 1 1 SOCS box SOCS_box PF07525.16 KFM82572.1 - 5e-12 46.0 2.5 1.2e-11 44.7 2.5 1.7 1 0 0 1 1 1 1 SOCS box SOCS_box PF07525.16 KFM82573.1 - 1.5e-12 47.6 2.6 1.5e-12 47.6 2.6 2.3 2 0 0 2 2 2 1 SOCS box Metallophos PF00149.28 KFM82575.1 - 0.00013 22.5 0.0 0.00014 22.4 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KFM82576.1 - 9.1e-06 26.3 0.0 1.5e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 KFM82576.1 - 5.3e-05 23.6 0.2 9.8e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM82576.1 - 0.0011 18.3 0.0 0.0079 15.7 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFM82576.1 - 0.0036 17.1 0.2 0.021 14.7 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain Bgal_small_N PF02929.17 KFM82578.1 - 0.0073 16.0 0.1 0.013 15.1 0.1 1.3 1 1 0 1 1 1 1 Beta galactosidase small chain YbbR PF07949.12 KFM82578.1 - 0.0087 16.4 0.9 0.0087 16.4 0.9 2.0 2 0 0 2 2 2 1 YbbR-like protein Pro_isomerase PF00160.21 KFM82579.1 - 1.1e-50 172.0 0.1 2e-50 171.2 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KFM82579.1 - 2.7e-11 43.8 1.2 0.0029 18.4 0.2 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM82579.1 - 0.00021 21.5 0.0 1 9.7 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain EIF4E-T PF10477.9 KFM82580.1 - 3.7e-28 98.8 19.1 4.3e-28 98.6 19.1 1.0 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E EIF4E-T PF10477.9 KFM82581.1 - 4.1e-07 29.2 61.2 1.7e-06 27.2 43.8 3.4 2 1 0 3 3 3 2 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Ribosomal_L19e PF01280.20 KFM82582.1 - 1.9e-51 173.9 11.8 1.9e-51 173.9 11.8 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e PFK PF00365.20 KFM82583.1 - 4.9e-41 140.9 1.3 6.2e-41 140.6 1.3 1.0 1 0 0 1 1 1 1 Phosphofructokinase EMI PF07546.13 KFM82584.1 - 1.4e-10 41.8 11.1 1.4e-10 41.8 11.1 2.8 3 1 0 3 3 3 1 EMI domain EGF_2 PF07974.13 KFM82584.1 - 6.2e-06 26.5 77.0 0.0013 19.1 12.0 7.0 6 1 1 7 7 7 3 EGF-like domain Laminin_EGF PF00053.24 KFM82584.1 - 1.3e-05 25.2 52.0 0.0018 18.4 11.1 3.9 1 1 2 3 3 3 2 Laminin EGF domain hEGF PF12661.7 KFM82584.1 - 0.0047 17.5 53.5 0.023 15.3 7.9 6.3 6 0 0 6 6 6 4 Human growth factor-like EGF DSL PF01414.19 KFM82584.1 - 0.046 14.0 13.1 0.046 14.0 13.1 3.8 3 0 0 3 3 3 0 Delta serrate ligand EGF PF00008.27 KFM82584.1 - 1.8 8.9 54.8 0.15 12.4 7.2 5.9 5 1 1 6 6 6 0 EGF-like domain Ribosomal_S7 PF00177.21 KFM82585.1 - 5.1e-26 91.1 0.3 5.5e-26 91.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-C2H2_4 PF13894.6 KFM82588.1 - 2.4e-12 46.6 66.1 0.025 15.4 0.9 9.6 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM82588.1 - 3.6e-06 26.6 1.0 3.6e-06 26.6 1.0 5.4 6 0 0 6 6 6 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFM82588.1 - 6.9e-06 26.2 72.0 0.0014 19.0 1.7 9.6 10 0 0 10 10 10 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM82588.1 - 6e-05 23.3 49.4 0.0094 16.3 2.9 8.5 8 1 0 8 8 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFM82588.1 - 0.022 15.0 3.3 0.022 15.0 3.3 8.1 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM82588.1 - 0.046 13.7 0.5 0.046 13.7 0.5 7.6 8 1 0 8 8 8 0 C2H2-type zinc finger zf-MYST PF17772.1 KFM82588.1 - 0.066 12.8 0.0 0.066 12.8 0.0 6.2 6 1 1 7 7 7 0 MYST family zinc finger domain zf_C2H2_ZHX PF18387.1 KFM82588.1 - 0.28 10.8 0.0 0.28 10.8 0.0 8.2 5 1 3 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 KFM82588.1 - 2.4 8.1 14.8 49 3.9 0.0 5.9 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) DOR PF14839.6 KFM82589.1 - 0.014 15.4 5.9 0.014 15.4 5.9 4.0 2 1 0 2 2 2 0 DOR family RhoGEF PF00621.20 KFM82590.1 - 9.8e-28 97.6 1.0 1.9e-27 96.7 1.0 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_10 PF17902.1 KFM82590.1 - 0.16 12.0 0.9 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 SH3 domain TB2_DP1_HVA22 PF03134.19 KFM82591.1 - 2e-27 94.9 5.1 2.9e-27 94.4 5.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Arm PF00514.23 KFM82593.1 - 4.8e-45 150.3 24.5 9.6e-07 28.6 0.2 11.1 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KFM82593.1 - 3.1e-10 39.2 5.2 3.7e-07 29.1 3.2 3.3 3 1 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 KFM82593.1 - 5.3e-08 33.2 8.6 0.00039 20.7 0.8 5.2 4 2 1 5 5 5 2 HEAT repeats KAP PF05804.12 KFM82593.1 - 1.6e-07 30.0 0.7 0.0088 14.2 0.3 3.3 3 0 0 3 3 3 3 Kinesin-associated protein (KAP) HEAT_EZ PF13513.6 KFM82593.1 - 2e-07 31.3 9.9 0.065 13.8 0.2 5.8 4 1 1 5 5 5 3 HEAT-like repeat Cnd1 PF12717.7 KFM82593.1 - 7.1e-07 29.4 2.2 0.002 18.2 0.5 3.7 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFM82593.1 - 1e-05 25.4 6.2 1.7 9.1 0.0 6.0 7 0 0 7 7 6 2 HEAT repeat V-ATPase_H_N PF03224.14 KFM82593.1 - 1.9e-05 24.1 3.6 0.017 14.4 2.7 3.2 1 1 1 2 2 2 1 V-ATPase subunit H DUF3361 PF11841.8 KFM82593.1 - 8.6e-05 22.5 3.5 2.3 8.1 0.0 4.8 3 2 2 5 5 5 2 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 KFM82593.1 - 0.0016 18.4 1.4 0.019 15.0 0.1 3.3 3 2 1 4 4 3 1 Spinocerebellar ataxia type 10 protein domain Pes-10 PF07149.11 KFM82593.1 - 0.022 13.9 0.3 0.39 9.7 0.0 2.4 2 1 0 2 2 2 0 Pes-10 Arm_2 PF04826.13 KFM82593.1 - 0.034 13.6 10.7 0.14 11.6 0.2 4.0 3 1 0 4 4 4 0 Armadillo-like RasGEF_N_2 PF14663.6 KFM82593.1 - 0.32 11.4 8.4 11 6.5 0.3 5.1 4 3 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF1387 PF07139.11 KFM82595.1 - 7e-32 111.4 7.2 7.5e-32 111.3 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) DUF2959 PF11172.8 KFM82595.1 - 0.06 13.5 3.4 0.077 13.1 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF2087 PF09860.9 KFM82595.1 - 0.081 13.1 1.4 6 7.1 0.4 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Tox-ODYAM1 PF15642.6 KFM82595.1 - 0.18 10.7 5.6 0.18 10.7 5.6 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Mt_ATP-synt_B PF05405.14 KFM82595.1 - 0.23 11.1 4.3 0.3 10.7 4.3 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Prominin PF05478.11 KFM82595.1 - 0.35 8.8 2.2 0.4 8.6 2.2 1.0 1 0 0 1 1 1 0 Prominin Phage_holin_3_6 PF07332.11 KFM82595.1 - 0.68 10.0 2.1 5.1 7.2 0.4 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III BRK PF07533.16 KFM82596.1 - 0.21 11.2 0.4 0.74 9.5 0.1 2.1 2 0 0 2 2 2 0 BRK domain Peptidase_S49_N PF08496.10 KFM82597.1 - 8.5 6.4 12.8 8.6 6.4 12.8 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PS_Dcarbxylase PF02666.15 KFM82599.1 - 1.3e-62 210.9 0.0 1.7e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PIF6 PF05341.11 KFM82601.1 - 0.076 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Per os infectivity factor 6 MARVEL PF01284.23 KFM82602.1 - 8.6e-21 74.5 11.5 1.1e-20 74.2 11.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain MIG-14_Wnt-bd PF06664.12 KFM82602.1 - 0.11 11.7 4.9 0.16 11.2 4.9 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Glyco_transf_92 PF01697.27 KFM82603.1 - 6.3e-45 153.9 1.1 8.7e-45 153.4 0.2 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFM82603.1 - 9.8e-07 29.2 0.1 2.9e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Shisa PF13908.6 KFM82603.1 - 0.083 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator adh_short PF00106.25 KFM82604.1 - 7.4e-47 159.3 0.0 8.8e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM82604.1 - 1.2e-36 126.4 0.0 1.4e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM82604.1 - 5.8e-11 42.6 0.1 7.8e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM82604.1 - 2e-06 27.5 0.0 4e-06 26.5 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFM82604.1 - 0.001 19.0 0.0 0.0041 17.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFM82604.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KFM82604.1 - 0.011 16.3 0.0 0.094 13.3 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KFM82604.1 - 0.058 12.4 0.1 0.083 11.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFM82604.1 - 0.084 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain HATPase_c PF02518.26 KFM82604.1 - 0.19 12.3 0.0 2.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3591 PF12157.8 KFM82605.1 - 1e-166 555.0 0.1 3.7e-166 553.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KFM82605.1 - 8.4e-43 144.3 3.3 1.8e-20 72.7 0.3 2.8 2 0 0 2 2 2 2 Bromodomain TBP-binding PF09247.11 KFM82605.1 - 6.2e-16 58.4 2.0 3.7e-15 55.9 2.6 2.1 2 0 0 2 2 2 1 TATA box-binding protein binding zf-CCHC_6 PF15288.6 KFM82605.1 - 8.6e-16 57.5 0.6 2.1e-15 56.3 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle fn3 PF00041.21 KFM82606.1 - 1.5e-47 159.9 10.6 2.7e-18 66.1 0.6 3.6 3 0 0 3 3 3 3 Fibronectin type III domain I-set PF07679.16 KFM82606.1 - 2.6e-43 146.0 0.2 1.9e-14 53.5 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM82606.1 - 2.7e-36 124.0 2.4 2.5e-11 44.0 0.0 4.0 4 0 0 4 4 3 3 Immunoglobulin domain ig PF00047.25 KFM82606.1 - 1.4e-29 102.1 2.7 4e-09 36.5 0.0 3.7 4 0 0 4 4 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFM82606.1 - 4.9e-27 94.1 0.1 1.4e-07 31.7 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFM82606.1 - 4.4e-11 42.9 0.6 0.00011 22.3 0.0 4.9 3 2 0 3 3 3 2 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFM82606.1 - 6.8e-08 33.0 13.0 3.5e-06 27.5 0.0 4.4 4 2 0 4 4 3 2 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFM82606.1 - 2e-07 31.0 0.3 0.35 10.9 0.0 4.0 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFM82606.1 - 5.3e-07 29.6 0.0 0.012 15.6 0.0 3.5 3 0 0 3 3 3 2 C17orf99 Ig domain C1-set PF07654.15 KFM82606.1 - 9.5e-06 25.9 1.6 1.1 9.7 0.1 3.9 4 0 0 4 4 3 2 Immunoglobulin C1-set domain Interfer-bind PF09294.10 KFM82606.1 - 6.2e-05 23.3 0.0 0.11 12.8 0.0 3.7 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Ig_6 PF18452.1 KFM82606.1 - 9.1e-05 21.9 0.0 1.1 8.9 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain V-set_CD47 PF08204.11 KFM82606.1 - 0.0001 22.2 0.3 1.3 9.0 0.0 3.3 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Ig_4 PF16680.5 KFM82606.1 - 0.00012 22.3 0.5 0.7 10.2 0.0 4.0 3 2 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain fn3_2 PF16893.5 KFM82606.1 - 0.0037 17.4 0.0 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain Herpes_gE PF02480.16 KFM82606.1 - 0.014 14.2 0.0 4.1 6.0 0.0 2.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Insulin_TMD PF17870.1 KFM82606.1 - 0.32 11.1 2.4 0.86 9.7 2.4 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment GPI-anchored PF10342.9 KFM82606.1 - 0.52 11.1 4.9 1.3e+02 3.4 0.0 5.5 7 1 1 8 8 6 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family EHN PF06441.12 KFM82607.1 - 1.4e-34 118.7 0.1 3.1e-34 117.6 0.1 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFM82607.1 - 2.3e-17 63.5 0.0 5.1e-17 62.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM82607.1 - 7.9e-06 26.6 0.0 1.8e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ras PF00071.22 KFM82608.1 - 2.6e-34 118.2 0.0 3e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM82608.1 - 9.4e-13 48.4 0.0 1.6e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dopey_N PF04118.14 KFM82609.1 - 9.7e-05 21.6 2.8 0.00028 20.1 2.8 1.9 1 1 0 1 1 1 1 Dopey, N-terminal HSBP1 PF06825.12 KFM82609.1 - 0.13 12.1 0.1 0.36 10.7 0.1 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CLASP_N PF12348.8 KFM82609.1 - 0.14 11.7 5.7 0.36 10.4 0.1 3.0 3 0 0 3 3 3 0 CLASP N terminal KxDL PF10241.9 KFM82610.1 - 7.1e-15 55.1 0.1 9.3e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein BAR PF03114.18 KFM82610.1 - 0.066 12.8 0.1 0.083 12.5 0.1 1.1 1 0 0 1 1 1 0 BAR domain Sas6_CC PF18594.1 KFM82611.1 - 0.13 12.0 1.2 0.32 10.8 1.2 1.7 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain SAND PF01342.21 KFM82612.1 - 0.017 14.8 0.7 0.019 14.6 0.7 1.1 1 0 0 1 1 1 0 SAND domain PP2C PF00481.21 KFM82613.1 - 2.6e-08 33.8 0.1 4.9e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KFM82614.1 - 1.5e-09 37.9 0.0 1.6e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C TSP_1 PF00090.19 KFM82617.1 - 1.4e-07 31.6 18.6 4.2e-05 23.7 1.7 2.7 2 1 0 2 2 2 2 Thrombospondin type 1 domain Lactamase_B PF00753.27 KFM82619.1 - 6.6e-15 55.6 0.3 7.1e-14 52.3 0.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFM82619.1 - 0.031 13.8 0.1 0.05 13.1 0.1 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Transposase_21 PF02992.14 KFM82619.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Transposase family tnp2 EphA2_TM PF14575.6 KFM82622.1 - 0.041 14.8 0.0 0.056 14.3 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LAX PF15681.5 KFM82622.1 - 0.087 11.6 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X Shisa PF13908.6 KFM82622.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Nucleoside_tran PF01733.18 KFM82624.1 - 2.3e-54 184.9 23.7 2.6e-53 181.4 19.0 2.9 2 1 0 2 2 2 1 Nucleoside transporter MRAP PF15183.6 KFM82624.1 - 3.7 7.6 6.6 12 5.9 5.7 2.4 1 1 0 1 1 1 0 Melanocortin-2 receptor accessory protein family PAXNEB PF05625.11 KFM82625.1 - 1e-93 314.4 0.0 1.3e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Glyco_hydro_35 PF01301.19 KFM82626.1 - 8.9e-98 327.8 0.0 1e-97 327.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KFM82626.1 - 1.3e-15 57.6 0.0 1.3e-13 51.1 0.0 2.1 1 1 0 1 1 1 1 Beta-galactosidase CPG4 PF15481.6 KFM82627.1 - 0.0012 19.4 3.1 0.0013 19.3 3.1 1.1 1 0 0 1 1 1 1 Chondroitin proteoglycan 4 DUF1397 PF07165.11 KFM82627.1 - 0.014 14.8 2.2 0.018 14.5 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) TAL_effector PF03377.13 KFM82628.1 - 0.049 14.0 0.7 0.23 11.8 0.7 2.0 1 1 0 1 1 1 0 TAL effector repeat Cation_efflux PF01545.21 KFM82630.1 - 3.6e-54 183.5 6.2 4.4e-54 183.2 6.2 1.1 1 0 0 1 1 1 1 Cation efflux family NPCC PF08058.11 KFM82630.1 - 2.4 8.2 5.0 2.2 8.4 0.8 2.3 2 1 0 2 2 2 0 Nuclear pore complex component Chromate_transp PF02417.15 KFM82630.1 - 9.8 6.3 9.9 20 5.3 4.7 2.2 2 0 0 2 2 2 0 Chromate transporter p450 PF00067.22 KFM82631.1 - 1.3e-107 360.5 0.2 6.5e-76 255.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF1837 PF08878.11 KFM82631.1 - 1.1 9.1 6.2 1.1 9.0 4.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1837) RRM_1 PF00076.22 KFM82632.1 - 5.6e-15 54.9 0.0 8.6e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFM82632.1 - 0.00012 22.0 6.5 0.00023 21.1 6.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KFM82632.1 - 0.011 15.6 6.2 0.017 14.9 6.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 KFM82632.1 - 0.037 13.7 5.6 0.098 12.4 5.6 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RRM_7 PF16367.5 KFM82632.1 - 0.046 13.8 0.0 0.2 11.8 0.0 2.1 1 0 0 1 1 1 0 RNA recognition motif zf-CCHC_3 PF13917.6 KFM82632.1 - 0.41 10.7 5.3 1.2 9.1 5.3 1.8 1 0 0 1 1 1 0 Zinc knuckle Pex16 PF08610.10 KFM82633.1 - 5.6e-15 55.3 0.0 6e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Pex16 PF08610.10 KFM82634.1 - 6.1e-48 163.7 0.1 7.1e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) ABC_membrane PF00664.23 KFM82636.1 - 5.6e-82 275.5 36.5 4.7e-43 147.8 9.0 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFM82636.1 - 3.7e-54 182.9 0.1 2.7e-28 99.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFM82636.1 - 6.8e-11 42.0 2.4 0.00083 18.9 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFM82636.1 - 7.3e-08 32.5 0.5 0.0014 18.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM82636.1 - 0.00026 20.9 1.4 0.073 13.0 0.3 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFM82636.1 - 0.00037 20.9 0.0 0.65 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFM82636.1 - 0.0022 17.7 4.3 0.082 12.7 0.4 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 KFM82636.1 - 0.0024 17.9 1.5 0.034 14.2 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 KFM82636.1 - 0.0027 17.3 0.1 0.49 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFM82636.1 - 0.0029 16.9 1.5 0.26 10.5 0.1 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_24 PF13479.6 KFM82636.1 - 0.005 16.6 0.5 0.096 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFM82636.1 - 0.0089 15.9 3.6 0.13 12.0 0.2 3.3 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFM82636.1 - 0.025 14.1 0.2 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 KFM82636.1 - 0.025 13.8 1.3 0.73 9.0 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain T2SSE PF00437.20 KFM82636.1 - 0.029 13.4 0.0 2.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 KFM82636.1 - 0.078 13.5 8.5 0.45 11.0 0.3 3.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KFM82636.1 - 0.088 12.5 1.0 4.7 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 KFM82636.1 - 0.14 10.9 0.6 8.1 5.1 0.2 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Roc PF08477.13 KFM82636.1 - 0.2 11.9 1.5 23 5.2 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KFM82636.1 - 0.29 11.4 3.2 10 6.4 0.1 3.0 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 KFM82636.1 - 0.31 11.0 1.3 54 3.7 0.1 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 KFM82636.1 - 0.67 9.6 5.9 0.9 9.2 0.4 2.9 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.17 KFM82636.1 - 3.5 7.6 10.6 2.2 8.3 0.2 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain UQ_con PF00179.26 KFM82637.1 - 2.8e-44 150.2 0.1 3.1e-44 150.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFM82637.1 - 4.5e-05 23.3 0.1 8.4e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 UEV domain RWD PF05773.22 KFM82637.1 - 0.00029 21.1 0.2 0.00039 20.7 0.2 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFM82637.1 - 0.0017 18.1 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF1154 PF06631.11 KFM82637.1 - 0.071 13.2 2.4 6 7.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) LRR_8 PF13855.6 KFM82639.1 - 2.8e-18 65.4 2.6 3.3e-09 36.4 0.1 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM82639.1 - 0.00036 20.9 4.6 0.02 15.3 0.1 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM82639.1 - 0.00054 19.9 0.0 0.00089 19.2 0.0 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFM82639.1 - 0.095 13.3 8.4 0.43 11.3 0.0 4.3 4 2 1 5 5 5 0 Leucine Rich Repeat Ig_3 PF13927.6 KFM82641.1 - 7.7e-10 39.2 0.7 4.3e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM82641.1 - 4.1e-07 30.1 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM82641.1 - 1.1e-06 28.6 0.0 0.053 13.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Adeno_E3_CR1 PF02440.15 KFM82641.1 - 0.0035 17.1 0.4 0.0096 15.7 0.1 1.7 2 0 0 2 2 2 1 Adenovirus E3 region protein CR1 V-set PF07686.17 KFM82641.1 - 0.064 13.4 0.0 6.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin V-set domain Ig_2 PF13895.6 KFM82641.1 - 0.067 13.5 0.1 3.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain UBN_AB PF14075.6 KFM82642.1 - 2.1e-72 243.3 3.4 2.1e-72 243.3 3.4 2.6 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 KFM82642.1 - 1e-18 67.1 2.1 2.6e-18 65.7 2.1 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Saf_2TM PF18303.1 KFM82643.1 - 0.021 14.4 0.1 0.024 14.3 0.1 1.0 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Erv26 PF04148.13 KFM82643.1 - 0.021 14.6 0.0 0.021 14.6 0.0 1.0 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 vATP-synt_E PF01991.18 KFM82645.1 - 1.9e-27 96.0 12.4 2.4e-27 95.7 12.4 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit SAM_DrpA PF18255.1 KFM82645.1 - 0.016 15.5 1.3 0.24 11.7 0.3 2.1 2 0 0 2 2 2 0 DNA processing protein A sterile alpha motif domain Cytochrome_cB PF11783.8 KFM82645.1 - 0.069 13.0 0.2 0.086 12.7 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c bacterial Gluconate_2-dh3 PF13618.6 KFM82645.1 - 0.16 12.2 3.3 0.2 11.9 3.3 1.1 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF1461 PF07314.11 KFM82645.1 - 0.62 9.9 3.4 1.1 9.2 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1461) Folliculin PF11704.8 KFM82645.1 - 0.98 9.3 4.5 1 9.2 4.5 1.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Tcf25 PF04910.14 KFM82647.1 - 1.1e-111 373.3 1.3 1.3e-111 373.0 1.3 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 LSM14 PF12701.7 KFM82648.1 - 5.7e-32 109.7 0.0 1.2e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KFM82648.1 - 4.2e-13 50.1 9.2 4.2e-13 50.1 9.2 2.5 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KFM82648.1 - 3.6e-08 33.4 0.0 7.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TAFH PF07531.14 KFM82649.1 - 1.4e-25 89.2 0.5 1.5e-25 89.1 0.5 1.0 1 0 0 1 1 1 1 NHR1 homology to TAF TFIIS_M PF07500.14 KFM82649.1 - 0.066 13.7 0.2 0.13 12.7 0.2 1.5 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain DUF2089 PF09862.9 KFM82649.1 - 0.087 12.9 0.1 0.098 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) TAF4 PF05236.14 KFM82650.1 - 7.3e-09 35.8 0.1 1.1e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Consortin_C PF15281.6 KFM82650.1 - 0.2 11.6 1.2 0.37 10.8 0.5 1.8 1 1 1 2 2 2 0 Consortin C-terminus TAF4 PF05236.14 KFM82651.1 - 2.3e-31 109.6 10.5 2.6e-31 109.4 10.5 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family BUD22 PF09073.10 KFM82653.1 - 5.3e-07 29.3 13.8 5.3e-07 29.3 13.8 3.5 1 1 1 2 2 2 1 BUD22 CBM_14 PF01607.24 KFM82654.1 - 4.3e-08 33.2 4.7 4.3e-08 33.2 4.7 1.6 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Sporozoite_P67 PF05642.11 KFM82654.1 - 0.015 13.5 1.7 0.018 13.1 1.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_M13 PF01431.21 KFM82655.1 - 3.2e-70 235.9 0.0 5.9e-70 235.0 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KFM82655.1 - 1.4e-64 219.2 0.4 2e-64 218.7 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_C48 PF02902.19 KFM82657.1 - 3.1e-39 135.0 2.4 3.7e-39 134.8 1.1 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain m04gp34like PF12216.8 KFM82657.1 - 0.022 14.3 0.2 0.022 14.3 0.2 1.7 2 0 0 2 2 2 0 Immune evasion protein DUF4286 PF14114.6 KFM82657.1 - 0.23 12.0 1.4 0.72 10.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) RWD PF05773.22 KFM82658.1 - 2.1e-23 82.8 1.4 4.4e-23 81.8 1.4 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KFM82658.1 - 1.7e-06 28.4 5.1 1.7e-06 28.4 5.1 1.9 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 PTPS PF01242.19 KFM82658.1 - 0.047 13.7 0.5 0.092 12.7 0.3 1.6 1 1 1 2 2 2 0 6-pyruvoyl tetrahydropterin synthase HAD_2 PF13419.6 KFM82659.1 - 3.5e-27 95.6 0.1 4.1e-27 95.4 0.1 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM82659.1 - 4.9e-16 59.6 0.3 2.2e-15 57.5 0.3 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KFM82659.1 - 0.00033 20.7 0.4 0.36 11.0 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM82659.1 - 0.0043 17.1 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KFM82659.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CLCA PF08434.11 KFM82660.1 - 5.1e-24 85.0 0.3 8.2e-21 74.5 0.0 2.2 1 1 1 2 2 2 2 Calcium-activated chloride channel N terminal fn3_4 PF16794.5 KFM82661.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 Fibronectin-III type domain Pkinase_Tyr PF07714.17 KFM82663.1 - 8.5e-06 25.2 0.1 8.9e-05 21.9 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4046 PF13255.6 KFM82663.1 - 0.056 14.0 0.1 0.56 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4046) JAB PF01398.21 KFM82664.1 - 2.4e-32 111.4 0.0 5.3e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BRCC36_C PF18110.1 KFM82664.1 - 3.9e-26 91.0 3.8 6.8e-26 90.2 3.8 1.4 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain Prok-JAB PF14464.6 KFM82664.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Cep57_CLD PF14073.6 KFM82664.1 - 3.6e-05 23.9 1.0 6.9e-05 22.9 1.0 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 Herpes_ICP4_N PF03584.15 KFM82664.1 - 0.19 11.6 0.0 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Ibs_toxin PF13956.6 KFM82665.1 - 0.046 13.7 2.0 0.091 12.8 2.0 1.5 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Pericardin_rpt PF07054.11 KFM82665.1 - 0.22 11.6 23.6 6.5 7.0 23.6 2.1 1 1 0 1 1 1 0 Pericardin like repeat zf-C2H2 PF00096.26 KFM82666.1 - 1e-05 25.7 14.6 0.0018 18.6 5.4 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 KFM82666.1 - 0.00014 22.2 3.2 0.037 14.4 1.2 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM82666.1 - 0.00069 20.3 13.0 0.01 16.6 4.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFM82666.1 - 0.0099 15.5 5.1 0.18 11.4 1.3 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-NADH-PPase PF09297.11 KFM82666.1 - 0.01 15.4 3.4 1.3 8.8 0.2 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C2H2_11 PF16622.5 KFM82666.1 - 0.013 15.2 3.2 0.013 15.2 3.2 2.2 2 1 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFM82666.1 - 0.015 15.6 8.9 0.13 12.6 1.7 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFM82666.1 - 0.021 15.0 0.8 0.068 13.3 0.8 1.8 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 KFM82666.1 - 0.03 14.2 1.8 0.76 9.7 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 KFM82666.1 - 0.031 14.6 4.3 1.1 9.7 1.4 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFM82666.1 - 0.032 14.7 15.1 0.063 13.7 2.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFM82666.1 - 0.039 14.0 2.4 0.039 14.0 2.4 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger OTT_1508_deam PF14441.6 KFM82666.1 - 0.065 13.3 5.1 0.1 12.6 1.0 2.0 1 1 1 2 2 2 0 OTT_1508-like deaminase IBR PF01485.21 KFM82666.1 - 0.067 13.4 3.4 2.7 8.3 0.4 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 KFM82666.1 - 0.11 12.5 2.3 0.17 11.9 2.3 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf_C2H2_ZHX PF18387.1 KFM82666.1 - 0.16 11.6 6.9 0.17 11.6 0.5 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2116 PF09889.9 KFM82666.1 - 0.47 10.5 4.6 7.3 6.7 1.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ROS_MUCR PF05443.11 KFM82666.1 - 0.5 10.4 4.1 3 7.9 0.7 2.0 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein NOB1_Zn_bind PF08772.11 KFM82666.1 - 0.5 10.6 5.4 6.9 6.9 0.8 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like GAGA PF09237.11 KFM82666.1 - 0.81 9.5 5.7 5 7.0 0.6 2.2 1 1 1 2 2 2 0 GAGA factor UPF0547 PF10571.9 KFM82666.1 - 1.8 8.8 6.3 7.4 6.7 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 MULE PF10551.9 KFM82667.1 - 3.3e-11 43.4 0.3 3e-10 40.4 0.1 2.8 3 0 0 3 3 3 1 MULE transposase domain zf-C2H2 PF00096.26 KFM82667.1 - 0.0045 17.4 16.6 0.051 14.1 3.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type FAR1 PF03101.15 KFM82667.1 - 0.03 15.0 0.4 0.1 13.3 0.4 1.9 1 0 0 1 1 1 0 FAR1 DNA-binding domain zf-met PF12874.7 KFM82667.1 - 0.26 11.8 9.6 1.9 9.0 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Forkhead PF00250.18 KFM82668.1 - 5e-37 126.0 0.1 7.8e-37 125.4 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain Pkinase PF00069.25 KFM82669.1 - 3.6e-66 223.2 0.0 4.5e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM82669.1 - 2.3e-38 131.9 0.0 2.8e-36 125.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM82669.1 - 0.0001 21.2 0.0 0.00016 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM82669.1 - 0.0049 15.9 0.0 0.0067 15.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFM82669.1 - 0.0059 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KFM82669.1 - 0.0086 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFM82669.1 - 0.027 14.4 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_4 PF13637.6 KFM82670.1 - 6.7e-11 42.5 0.2 1.4e-06 28.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM82670.1 - 7.6e-10 38.8 0.1 1.8e-06 28.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFM82670.1 - 1.5e-08 35.1 0.5 1.7e-05 25.3 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) LEM PF03020.15 KFM82670.1 - 1.6e-08 33.9 0.0 3.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 LEM domain Ank_3 PF13606.6 KFM82670.1 - 8.8e-08 31.9 0.9 0.0069 16.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFM82670.1 - 5.9e-06 26.5 1.4 0.0029 17.9 0.4 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) AAA PF00004.29 KFM82671.1 - 1.7e-41 141.8 0.0 3.7e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFM82671.1 - 4.8e-18 64.8 0.1 1e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFM82671.1 - 1.7e-08 34.2 0.3 5.7e-08 32.4 0.3 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFM82671.1 - 5.1e-06 27.0 0.3 0.0019 18.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFM82671.1 - 1.2e-05 25.4 0.6 0.00011 22.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFM82671.1 - 7.1e-05 22.6 0.0 0.0002 21.1 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFM82671.1 - 0.00012 22.4 0.5 0.063 13.5 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KFM82671.1 - 0.00014 22.0 0.5 0.0006 20.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFM82671.1 - 0.0023 17.1 0.0 0.005 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 KFM82671.1 - 0.0055 16.5 1.1 0.58 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KFM82671.1 - 0.019 14.3 1.1 0.048 13.0 0.0 2.2 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 KFM82671.1 - 0.02 14.3 0.1 0.056 12.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KFM82671.1 - 0.023 14.2 1.1 0.055 12.9 0.0 2.1 3 0 0 3 3 3 0 PhoH-like protein Dsl1_C PF11989.8 KFM82671.1 - 0.025 14.3 0.6 0.044 13.5 0.6 1.3 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal AAA_7 PF12775.7 KFM82671.1 - 0.027 14.0 0.0 0.066 12.7 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KFM82671.1 - 0.03 14.0 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KFM82671.1 - 0.031 14.0 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFM82671.1 - 0.049 13.8 0.3 0.16 12.1 0.0 2.1 3 0 0 3 3 2 0 AAA domain Atg14 PF10186.9 KFM82671.1 - 0.054 12.6 1.5 0.082 12.0 1.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_25 PF13481.6 KFM82671.1 - 0.055 13.1 1.1 0.57 9.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain DUF3713 PF12506.8 KFM82671.1 - 0.062 13.6 0.7 0.4 11.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) AAA_18 PF13238.6 KFM82671.1 - 0.062 13.8 0.3 0.29 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFM82671.1 - 0.063 13.0 1.5 0.13 12.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFM82671.1 - 0.068 13.6 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DUF812 PF05667.11 KFM82671.1 - 0.089 11.7 6.8 0.15 10.9 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) JIP_LZII PF16471.5 KFM82671.1 - 0.1 12.8 6.8 0.28 11.4 6.8 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II EGF_CA PF07645.15 KFM82672.1 - 1.8e-20 72.9 70.1 8.2e-08 32.3 10.1 6.8 4 2 2 6 6 6 6 Calcium-binding EGF domain EGF_3 PF12947.7 KFM82672.1 - 1.1e-12 47.9 81.4 3e-05 24.1 4.1 7.4 8 1 0 8 8 8 6 EGF domain cEGF PF12662.7 KFM82672.1 - 4.9e-09 36.0 63.8 2.4e-06 27.4 2.4 8.0 8 0 0 8 8 8 6 Complement Clr-like EGF-like COMP PF11598.8 KFM82672.1 - 3.6e-07 30.5 7.2 3.6e-07 30.5 7.2 1.8 2 0 0 2 2 2 1 Cartilage oligomeric matrix protein EGF PF00008.27 KFM82672.1 - 0.0002 21.6 86.7 0.031 14.6 5.7 7.4 6 1 0 6 6 6 4 EGF-like domain adh_short PF00106.25 KFM82673.1 - 3.1e-46 157.3 0.0 3.7e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM82673.1 - 3.5e-28 98.7 0.0 4.3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM82673.1 - 3.2e-11 43.5 0.0 5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFM82673.1 - 0.0085 15.3 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Patched PF02460.18 KFM82674.1 - 3.3e-07 28.8 14.3 8.1e-07 27.5 13.8 1.5 1 1 1 2 2 2 1 Patched family MMPL PF03176.15 KFM82674.1 - 2.7e-05 23.3 10.2 4.4e-05 22.6 10.2 1.3 1 0 0 1 1 1 1 MMPL family DUF2207 PF09972.9 KFM82674.1 - 0.0067 15.2 1.9 0.0067 15.2 1.9 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) SKG6 PF08693.10 KFM82674.1 - 0.023 14.1 0.8 0.58 9.6 0.2 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sterol-sensing PF12349.8 KFM82674.1 - 0.077 12.8 12.3 0.079 12.8 11.4 1.5 1 1 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation Rax2 PF12768.7 KFM82674.1 - 0.087 12.3 1.8 0.11 11.9 0.2 1.9 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Terpene_synth_C PF03936.16 KFM82674.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain ACR_tran PF00873.19 KFM82674.1 - 0.71 7.4 7.0 0.88 7.1 7.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Sterol-sensing PF12349.8 KFM82675.1 - 8.2e-10 38.7 16.0 1.6e-09 37.8 16.0 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFM82675.1 - 1.1e-08 33.7 18.0 1.1e-08 33.7 18.0 2.0 2 0 0 2 2 2 1 Patched family MMPL PF03176.15 KFM82675.1 - 0.0046 15.9 12.7 0.0082 15.1 12.7 1.3 1 0 0 1 1 1 1 MMPL family ADP_PFK_GK PF04587.15 KFM82676.1 - 3.2e-137 457.6 0.0 3.9e-137 457.3 0.0 1.1 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Gtr1_RagA PF04670.12 KFM82676.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DHDPS PF00701.22 KFM82677.1 - 0.022 13.5 0.0 0.024 13.3 0.0 1.0 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family FtsJ PF01728.19 KFM82678.1 - 1e-23 84.4 0.0 2.1e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3966 PF13110.6 KFM82680.1 - 0.47 10.4 3.8 0.33 10.9 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3966) Na_Ca_ex PF01699.24 KFM82683.1 - 5.1e-09 36.2 1.2 7.5e-09 35.7 1.2 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 KFM82684.1 - 1.5e-25 89.9 16.3 1.5e-25 89.9 16.3 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein OAD_gamma PF04277.13 KFM82684.1 - 0.0048 17.4 0.0 0.0048 17.4 0.0 3.1 3 0 0 3 3 3 1 Oxaloacetate decarboxylase, gamma chain Connexin PF00029.19 KFM82684.1 - 0.0083 15.9 0.2 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 Connexin EVC2_like PF12297.8 KFM82684.1 - 0.15 10.7 0.7 0.31 9.7 0.0 1.8 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Shisa PF13908.6 KFM82684.1 - 0.17 12.1 1.9 0.94 9.7 2.1 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Mss4 PF04421.13 KFM82684.1 - 0.25 11.5 1.0 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Mss4 protein TMEM208_SND2 PF05620.11 KFM82684.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Orthoreo_P10 PF07204.11 KFM82684.1 - 1.6 8.7 6.9 1.8 8.6 1.1 3.1 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 Dysbindin PF04440.16 KFM82686.1 - 8.9e-05 22.7 5.5 0.00016 21.9 5.5 1.4 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) Glyco_hydro_47 PF01532.20 KFM82686.1 - 0.0078 15.2 0.6 0.0087 15.0 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IncFII_repA PF02387.15 KFM82686.1 - 0.068 12.4 3.4 0.083 12.1 3.4 1.1 1 0 0 1 1 1 0 IncFII RepA protein family NUP50 PF08911.11 KFM82686.1 - 0.61 10.8 3.9 1.1 9.9 2.8 2.0 1 1 1 2 2 2 0 NUP50 (Nucleoporin 50 kDa) TraB PF01963.17 KFM82687.1 - 1.1e-36 127.1 0.0 1.3e-36 126.8 0.0 1.1 1 0 0 1 1 1 1 TraB family OATP PF03137.20 KFM82688.1 - 1.5e-168 561.5 9.1 4.9e-168 559.8 9.1 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFM82688.1 - 1.1e-18 67.3 23.4 3.9e-15 55.6 7.3 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 KFM82688.1 - 0.0012 18.9 10.0 0.0012 18.9 10.0 2.9 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain VMA21 PF09446.10 KFM82688.1 - 0.018 15.2 0.8 0.018 15.2 0.8 3.6 5 0 0 5 5 5 0 VMA21-like domain Kazal_1 PF00050.21 KFM82688.1 - 0.24 11.4 14.3 0.069 13.2 4.4 3.2 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain Wzy_C PF04932.15 KFM82688.1 - 0.66 9.6 5.3 5.8 6.5 0.0 4.1 3 2 0 3 3 3 0 O-Antigen ligase Polysacc_deac_1 PF01522.21 KFM82689.1 - 1.1e-10 41.5 0.0 4.9e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase TPD52 PF04201.15 KFM82690.1 - 4.7e-34 117.4 9.8 1e-32 113.0 9.8 2.0 1 1 0 1 1 1 1 Tumour protein D52 family Swi5 PF07061.11 KFM82690.1 - 0.19 11.8 0.8 1.1 9.4 0.8 2.1 1 1 0 1 1 1 0 Swi5 RapH_N PF18801.1 KFM82690.1 - 0.45 10.6 2.3 3.6 7.8 0.0 2.7 2 1 1 3 3 3 0 response regulator aspartate phosphatase H, N terminal MCLC PF05934.11 KFM82691.1 - 3.1e-14 52.7 9.4 6.2e-14 51.6 9.4 1.6 1 1 0 1 1 1 1 Mid-1-related chloride channel (MCLC) Secretogranin_V PF05281.11 KFM82692.1 - 2.2e-28 99.4 0.2 2.9e-28 99.1 0.2 1.1 1 0 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) Nucleos_tra2_N PF01773.20 KFM82692.1 - 0.13 12.9 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus Periviscerokin PF08259.11 KFM82695.1 - 0.17 12.2 1.8 26 5.5 0.2 3.6 3 0 0 3 3 3 0 Periviscerokinin family Pkinase PF00069.25 KFM82696.1 - 3.4e-72 243.0 0.0 4e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM82696.1 - 8.1e-37 126.9 0.0 9.6e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM82696.1 - 4.6e-05 22.9 0.0 0.0025 17.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFM82696.1 - 8.7e-05 21.5 0.0 0.0003 19.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFM82696.1 - 8.7e-05 22.0 0.1 0.00016 21.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM82696.1 - 0.03 14.2 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Bombinin PF05298.11 KFM82696.1 - 0.089 12.5 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Bombinin DUF1667 PF07892.11 KFM82697.1 - 0.029 14.4 0.0 0.13 12.3 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) Troponin PF00992.20 KFM82699.1 - 4.8e-10 39.9 9.6 4.8e-10 39.9 9.6 4.5 3 2 2 5 5 5 2 Troponin Troponin PF00992.20 KFM82702.1 - 1.7e-44 151.4 12.6 1.7e-44 151.4 12.6 2.1 2 0 0 2 2 2 1 Troponin vATP-synt_AC39 PF01992.16 KFM82706.1 - 0.031 13.8 0.2 0.046 13.2 0.2 1.2 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit Dynactin_p22 PF07426.11 KFM82708.1 - 2e-48 164.4 5.9 2.3e-48 164.2 5.9 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 SKA2 PF16740.5 KFM82708.1 - 0.02 14.6 3.9 0.04 13.7 0.8 2.5 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 RNase_Zc3h12a PF11977.8 KFM82708.1 - 0.096 12.5 0.2 0.21 11.3 0.2 1.6 1 1 1 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain CCDC85 PF10226.9 KFM82708.1 - 0.099 12.3 1.5 0.13 11.9 0.1 1.8 1 1 1 2 2 2 0 CCDC85 family DUF948 PF06103.11 KFM82708.1 - 0.11 12.8 2.7 0.32 11.3 0.1 2.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Poly_export PF02563.16 KFM82709.1 - 1.7e-05 24.9 0.0 11 6.3 0.0 4.6 1 1 4 5 5 5 3 Polysaccharide biosynthesis/export protein Ephrin_rec_like PF07699.13 KFM82709.1 - 0.00018 21.2 23.5 0.016 15.0 5.9 4.3 1 1 3 4 4 4 3 Putative ephrin-receptor like Anti-TRAP PF15777.5 KFM82709.1 - 0.12 12.4 22.3 0.66 10.0 4.4 3.6 1 1 5 6 6 6 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2080 PF09853.9 KFM82709.1 - 3.1 7.6 11.8 45 3.9 0.1 4.8 2 1 3 5 5 5 0 Putative transposon-encoded protein (DUF2080) zf-C3HC PF07967.13 KFM82711.1 - 1.4e-22 80.2 0.9 1.8e-22 79.8 0.9 1.2 1 0 0 1 1 1 1 C3HC zinc finger-like Rsm1 PF08600.10 KFM82711.1 - 0.15 12.2 5.6 0.28 11.4 4.5 2.0 2 1 0 2 2 2 0 Rsm1-like DcpS_C PF11969.8 KFM82712.1 - 8.5e-28 97.1 0.8 1.8e-27 96.1 0.8 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KFM82712.1 - 1.3e-13 51.6 0.1 3.8e-13 50.2 0.1 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal RRP7 PF12923.7 KFM82713.1 - 1.6e-31 108.9 9.3 2.4e-31 108.3 9.3 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KFM82713.1 - 8.6e-09 35.4 0.1 2.2e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain DUF5093 PF17011.5 KFM82713.1 - 0.00096 19.4 1.7 0.00096 19.4 1.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5093) RRM_1 PF00076.22 KFM82713.1 - 0.013 15.3 0.8 2.8 7.8 0.0 2.9 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM82713.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF45 PF01863.17 KFM82713.1 - 2.1 8.4 5.5 26 4.8 3.6 2.1 1 1 0 2 2 2 0 Protein of unknown function DUF45 HMG_box PF00505.19 KFM82714.1 - 8.3e-20 71.0 1.6 8.3e-20 71.0 1.6 2.5 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM82714.1 - 7.9e-12 45.6 2.0 7.9e-12 45.6 2.0 2.2 1 1 1 2 2 2 1 HMG-box domain DUF812 PF05667.11 KFM82714.1 - 0.00046 19.2 8.4 0.00055 19.0 8.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF4407 PF14362.6 KFM82714.1 - 0.086 12.2 5.6 0.12 11.7 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCC-bdg_PDZ PF10506.9 KFM82714.1 - 0.31 11.1 4.4 0.69 10.0 4.4 1.6 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMCO5 PF14992.6 KFM82714.1 - 4.6 6.7 15.3 0.24 11.0 5.6 2.1 2 0 0 2 2 2 0 TMCO5 family CiPC PF15800.5 KFM82716.1 - 0.0063 16.3 5.4 0.0081 15.9 5.4 1.1 1 0 0 1 1 1 1 Clock interacting protein circadian Miga PF10265.9 KFM82716.1 - 3.4 6.5 5.6 4.6 6.1 5.6 1.1 1 0 0 1 1 1 0 Mitoguardin EGF PF00008.27 KFM82718.1 - 2.9e-05 24.3 4.8 2.9e-05 24.3 4.8 3.4 3 1 0 3 3 3 1 EGF-like domain EGF_MSP1_1 PF12946.7 KFM82718.1 - 0.016 15.2 12.5 0.016 15.2 12.5 2.4 2 0 0 2 2 2 0 MSP1 EGF domain 1 EGF_2 PF07974.13 KFM82718.1 - 0.039 14.3 8.3 0.039 14.3 8.3 3.5 2 2 1 3 3 3 0 EGF-like domain UPF0560 PF10577.9 KFM82718.1 - 0.095 11.2 1.2 0.11 10.9 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 T2SSM PF04612.12 KFM82718.1 - 0.16 12.1 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M LAX PF15681.5 KFM82718.1 - 0.38 9.5 0.6 0.59 8.9 0.2 1.5 2 0 0 2 2 2 0 Lymphocyte activation family X WD40 PF00400.32 KFM82719.1 - 0.045 14.6 0.0 0.096 13.6 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat SH2 PF00017.24 KFM82720.1 - 1.4e-11 44.3 0.2 2.8e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 SH2 domain DUF2547 PF10818.8 KFM82720.1 - 0.011 16.7 0.1 0.026 15.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Hamartin PF04388.12 KFM82720.1 - 0.43 9.2 8.6 0.6 8.7 8.6 1.2 1 0 0 1 1 1 0 Hamartin protein CPSF100_C PF13299.6 KFM82720.1 - 8.6 6.5 6.9 1 9.5 0.3 2.1 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Nucleoside_tran PF01733.18 KFM82721.1 - 7.7e-24 84.6 5.3 9.1e-24 84.4 5.3 1.0 1 0 0 1 1 1 1 Nucleoside transporter Peptidase_U4 PF03419.13 KFM82721.1 - 0.03 13.6 3.3 0.029 13.7 3.3 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA SQHop_cyclase_N PF13249.6 KFM82721.1 - 0.14 11.2 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain Nucleoside_tran PF01733.18 KFM82722.1 - 1.8e-09 37.4 0.4 1.9e-09 37.4 0.4 1.1 1 0 0 1 1 1 1 Nucleoside transporter Nucleoside_tran PF01733.18 KFM82723.1 - 0.00029 20.3 0.9 0.00029 20.3 0.9 1.9 1 1 1 2 2 2 1 Nucleoside transporter DUF3290 PF11694.8 KFM82723.1 - 0.18 11.8 1.7 0.21 11.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Daxx PF03344.15 KFM82725.1 - 0.0067 16.5 0.9 0.012 15.7 0.2 1.9 2 0 0 2 2 2 1 Daxx N-terminal Rassf1C-interacting domain Helitron_like_N PF14214.6 KFM82727.1 - 6.7e-27 94.9 0.0 7e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KFM82728.1 - 3.6e-37 128.4 0.0 5.4e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFM82728.1 - 2.3e-05 24.2 0.0 3.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFM82728.1 - 0.1 12.6 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2790 PF10976.8 KFM82729.1 - 0.099 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) zf-C2H2 PF00096.26 KFM82730.1 - 4.1e-06 26.9 23.3 0.032 14.7 1.3 5.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 KFM82730.1 - 6.2e-06 26.4 19.9 0.03 14.7 0.1 4.9 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM82730.1 - 5.8e-05 23.6 34.4 0.0077 17.0 0.8 6.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM82730.1 - 0.0045 16.9 0.5 0.0045 16.9 0.5 3.3 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFM82730.1 - 0.006 16.8 19.1 0.3 11.4 0.7 5.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Stc1 PF12898.7 KFM82730.1 - 0.042 14.4 0.8 0.042 14.4 0.8 5.1 4 1 0 4 4 4 0 Stc1 domain PID PF00640.23 KFM82731.1 - 5.8e-07 29.6 0.2 1.5e-06 28.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) Peptidase_M48 PF01435.18 KFM82732.1 - 8.2e-34 117.1 0.0 1.1e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 WASH_WAHD PF11945.8 KFM82732.1 - 0.027 14.0 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 WAHD domain of WASH complex AMPK1_CBM PF16561.5 KFM82734.1 - 1.3e-30 105.4 0.1 2.2e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KFM82734.1 - 1.5e-19 70.0 2.1 2.9e-19 69.1 2.1 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KFM82734.1 - 0.099 13.0 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) zf-C3HC4_3 PF13920.6 KFM82735.1 - 2.9e-09 36.6 7.4 2.9e-09 36.6 7.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM82735.1 - 1.4e-07 31.7 10.5 1.4e-07 31.7 10.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KFM82735.1 - 2.3e-06 27.8 4.7 6.5e-06 26.3 4.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFM82735.1 - 3.8e-06 26.6 7.7 3.8e-06 26.6 7.7 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFM82735.1 - 6.5e-06 25.9 10.4 6.5e-06 25.9 10.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM82735.1 - 9.2e-06 25.4 11.2 9.2e-06 25.4 11.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM82735.1 - 4e-05 23.6 5.9 0.00019 21.4 3.9 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM82735.1 - 0.00067 19.6 8.8 0.00067 19.6 8.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM82735.1 - 0.0028 17.8 9.3 0.017 15.2 8.5 2.7 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFM82735.1 - 0.008 16.2 1.4 0.019 15.0 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 KFM82735.1 - 0.024 14.5 0.4 2.1 8.3 0.0 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Vps51 PF08700.11 KFM82735.1 - 0.039 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Vps51/Vps67 Utp13 PF08625.11 KFM82735.1 - 0.048 13.6 0.1 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain zf-RING_4 PF14570.6 KFM82735.1 - 1.7 8.5 13.7 0.1 12.4 7.1 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain EGF PF00008.27 KFM82736.1 - 0.013 15.8 10.4 0.013 15.8 10.4 2.6 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 KFM82736.1 - 0.038 14.4 15.8 0.038 14.4 15.8 2.6 2 0 0 2 2 2 0 EGF-like domain RHS_repeat PF05593.14 KFM82737.1 - 8.9e-11 42.1 0.3 0.0038 17.7 0.0 4.4 4 0 0 4 4 4 2 RHS Repeat NHL PF01436.21 KFM82737.1 - 1.1e-05 25.2 0.9 4.5 7.5 0.1 6.5 7 0 0 7 7 7 2 NHL repeat Ras PF00071.22 KFM82739.1 - 1e-14 54.4 0.1 1.4e-06 28.0 0.1 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFM82739.1 - 3.8e-09 36.8 0.5 3.1e-07 30.6 0.3 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM82739.1 - 1.9e-08 34.0 0.1 0.0034 16.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM82739.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.11 KFM82739.1 - 0.002 17.0 0.8 0.012 14.5 0.8 2.0 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) DUF4600 PF15372.6 KFM82739.1 - 0.015 15.7 2.3 0.14 12.6 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) DUF3788 PF12663.7 KFM82739.1 - 0.044 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) AAA_14 PF13173.6 KFM82739.1 - 0.15 12.1 0.4 0.84 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.9 KFM82740.1 - 0.0013 18.4 20.8 0.0015 18.2 20.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF5427 PF10310.9 KFM82740.1 - 0.34 9.8 16.6 0.4 9.6 16.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SOBP PF15279.6 KFM82740.1 - 0.48 11.0 11.5 0.54 10.8 11.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein SRP-alpha_N PF04086.13 KFM82740.1 - 0.53 10.1 15.8 0.59 10.0 15.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.9 KFM82740.1 - 0.94 8.0 13.4 1 7.9 13.4 1.0 1 0 0 1 1 1 0 Macoilin family RNA_pol_Rpc4 PF05132.14 KFM82740.1 - 1.4 9.3 10.0 1.9 8.9 10.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pannexin_like PF12534.8 KFM82740.1 - 1.7 7.6 7.9 2.1 7.4 7.9 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 SelP_N PF04592.14 KFM82740.1 - 2.2 7.6 12.1 2.6 7.4 12.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RR_TM4-6 PF06459.12 KFM82740.1 - 2.5 7.9 12.4 2.8 7.7 12.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 KFM82740.1 - 2.6 7.2 11.1 2.7 7.1 11.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 KFM82740.1 - 2.9 7.9 6.9 3.1 7.8 6.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Use1 PF09753.9 KFM82740.1 - 3.4 7.3 10.8 4.2 7.0 10.8 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 TMEM214 PF10151.9 KFM82740.1 - 3.4 6.0 9.4 3.5 6.0 9.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator NARP1 PF12569.8 KFM82740.1 - 4.1 6.2 11.0 4.3 6.1 11.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CCDC106 PF15794.5 KFM82740.1 - 4.3 7.0 15.3 5.3 6.7 15.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Connexin PF00029.19 KFM82740.1 - 4.5 6.9 5.9 4.9 6.8 5.9 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 KFM82740.1 - 6 5.5 12.8 6.5 5.4 12.8 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KFM82740.1 - 6.2 5.0 13.3 6.2 5.0 13.3 1.0 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 KFM82740.1 - 9.6 4.9 7.4 10 4.9 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Aldo_ket_red PF00248.21 KFM82741.1 - 7.4e-11 41.8 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Slu7 PF11708.8 KFM82742.1 - 1.1e-87 294.2 11.9 1.1e-87 294.2 11.9 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KFM82742.1 - 0.021 14.5 1.0 0.043 13.6 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle eIF3_subunit PF08597.10 KFM82743.1 - 0.043 13.7 24.7 0.053 13.4 24.7 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TFIIF_alpha PF05793.12 KFM82743.1 - 0.051 12.2 24.5 0.061 11.9 24.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Dsh_C PF12316.8 KFM82743.1 - 0.19 12.1 11.7 0.21 12.0 11.7 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal POX PF07526.11 KFM82743.1 - 0.4 11.3 12.6 0.51 10.9 12.6 1.2 1 0 0 1 1 1 0 Associated with HOX Apt1 PF10351.9 KFM82743.1 - 0.64 8.8 18.8 0.74 8.6 18.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC53 PF10152.9 KFM82743.1 - 1.2 9.5 12.4 1.6 9.2 12.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SR-25 PF10500.9 KFM82743.1 - 1.6 8.3 36.2 1.6 8.3 9.0 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2828 PF11443.8 KFM82743.1 - 3.2 5.7 15.2 3.9 5.5 15.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DDHD PF02862.17 KFM82743.1 - 4.6 7.3 10.1 5.6 7.1 10.1 1.2 1 0 0 1 1 1 0 DDHD domain PPL5 PF18168.1 KFM82743.1 - 5 6.3 13.8 6.2 6.0 13.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF1943 PF09172.11 KFM82743.1 - 5.8 6.1 10.3 6 6.0 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Presenilin PF01080.17 KFM82743.1 - 6.6 5.4 15.8 7.4 5.2 15.8 1.0 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.12 KFM82743.1 - 7.9 5.8 23.1 9.8 5.4 23.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.13 KFM82743.1 - 9.2 4.9 17.9 11 4.7 17.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 IRF-2BP1_2 PF11261.8 KFM82744.1 - 0.087 12.4 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger Closter_coat PF01785.17 KFM82745.1 - 0.0035 16.6 0.2 0.0039 16.5 0.2 1.1 1 0 0 1 1 1 1 Closterovirus coat protein UIM PF02809.20 KFM82745.1 - 0.59 10.2 0.0 0.59 10.2 0.0 3.4 4 1 0 4 4 4 0 Ubiquitin interaction motif Josephin PF02099.17 KFM82746.1 - 3.3e-09 37.0 1.5 3.6e-09 36.9 1.5 1.0 1 0 0 1 1 1 1 Josephin PDZ_6 PF17820.1 KFM82747.1 - 5.2e-21 74.3 0.1 7.8e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFM82747.1 - 9.9e-20 70.7 4.9 2.3e-11 43.9 0.2 2.7 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFM82747.1 - 1.8e-11 44.2 3.7 1.3e-08 35.0 0.0 2.9 2 1 1 3 3 3 2 PDZ domain GRASP55_65 PF04495.14 KFM82747.1 - 0.024 14.9 0.1 0.098 13.0 0.1 2.0 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain DUF1459 PF07312.11 KFM82747.1 - 2.9 8.2 17.1 9.5 6.5 17.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1459) GN3L_Grn1 PF08701.11 KFM82748.1 - 4.2e-22 78.0 18.1 4.2e-22 78.0 18.1 3.5 3 1 1 4 4 4 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KFM82748.1 - 8.9e-17 61.2 0.2 2e-13 50.4 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM82748.1 - 4.4e-12 45.8 0.0 7.9e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM82748.1 - 4.7e-05 23.4 3.6 0.064 13.2 0.1 2.8 2 1 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 KFM82748.1 - 8.5e-05 22.2 0.0 0.0014 18.3 0.0 2.7 1 1 2 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFM82748.1 - 0.052 12.9 2.3 0.13 11.5 0.2 2.4 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 KFM82748.1 - 3.3 7.7 10.0 0.34 11.0 0.6 3.2 3 2 1 4 4 4 0 Dynamin family p450 PF00067.22 KFM82750.1 - 1.7e-56 191.9 0.0 2.1e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ARL6IP6 PF15062.6 KFM82750.1 - 0.096 12.8 0.2 0.24 11.6 0.2 1.6 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix PspB PF06667.12 KFM82750.1 - 0.17 12.0 1.2 0.43 10.7 1.2 1.7 1 0 0 1 1 1 0 Phage shock protein B p450 PF00067.22 KFM82751.1 - 1.1e-11 44.2 0.1 1.1e-11 44.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM82752.1 - 2.2e-66 224.5 0.0 2.6e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tmemb_161AB PF10268.9 KFM82753.1 - 1.2e-128 429.8 0.8 1.4e-128 429.5 0.8 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Ribonuclease_3 PF00636.26 KFM82755.1 - 6.7e-49 164.9 0.2 6e-26 91.1 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFM82755.1 - 2.4e-26 92.4 0.3 2e-10 40.9 0.0 4.4 4 0 0 4 4 4 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KFM82755.1 - 4.1e-26 91.0 3.2 5e-25 87.5 0.1 3.1 4 0 0 4 4 4 1 Dicer dimerisation domain PAZ PF02170.22 KFM82755.1 - 6.4e-17 61.7 2.4 1.3e-16 60.7 2.4 1.5 1 0 0 1 1 1 1 PAZ domain dsrm PF00035.26 KFM82755.1 - 1.6e-10 41.5 1.3 5.9e-06 26.9 0.1 3.1 3 0 0 3 3 3 2 Double-stranded RNA binding motif RlmM_FDX PF18125.1 KFM82755.1 - 0.073 13.6 0.0 0.43 11.1 0.0 2.2 2 0 0 2 2 2 0 RlmM ferredoxin-like domain IPK PF03770.16 KFM82757.1 - 1.4e-38 132.7 0.6 5.9e-38 130.7 0.6 1.9 1 1 0 1 1 1 1 Inositol polyphosphate kinase Btz PF09405.10 KFM82758.1 - 9.6e-21 74.4 7.6 9.6e-21 74.4 7.6 3.0 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding OCRE PF17780.1 KFM82760.1 - 3.4e-18 65.4 19.7 7.9e-18 64.2 19.7 1.7 1 0 0 1 1 1 1 OCRE domain zf-RanBP PF00641.18 KFM82760.1 - 3.8e-06 26.1 3.5 3.8e-06 26.1 3.5 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KFM82760.1 - 0.00022 21.0 0.0 0.00056 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_11 PF16622.5 KFM82760.1 - 0.0014 18.3 0.7 0.0014 18.3 0.7 1.8 2 0 0 2 2 2 1 zinc-finger C2H2-type OTT_1508_deam PF14441.6 KFM82760.1 - 0.036 14.1 0.8 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 OTT_1508-like deaminase TackOD1 PF18551.1 KFM82760.1 - 0.078 12.6 0.3 0.078 12.6 0.3 2.7 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 zf-C2H2_4 PF13894.6 KFM82760.1 - 0.079 13.8 2.5 0.11 13.4 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Perm-CXXC PF15629.6 KFM82760.1 - 0.14 12.5 1.6 0.34 11.2 1.6 1.6 1 0 0 1 1 1 0 Permuted single zf-CXXC unit DUF3725 PF12523.8 KFM82760.1 - 0.18 12.1 0.9 0.67 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) DZR PF12773.7 KFM82760.1 - 0.79 9.8 6.1 0.81 9.8 3.4 2.1 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2 PF00096.26 KFM82760.1 - 3.2 8.4 8.3 0.32 11.5 0.3 2.6 2 1 0 2 2 2 0 Zinc finger, C2H2 type TUDOR PF00567.24 KFM82761.1 - 1.4e-18 67.0 0.0 2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Tudor domain RRM_1 PF00076.22 KFM82762.1 - 5.4e-13 48.6 0.3 1.7e-12 46.9 0.3 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM82762.1 - 0.00016 21.3 0.1 0.0003 20.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KFM82762.1 - 0.00033 20.5 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) Ras PF00071.22 KFM82763.1 - 0.00052 19.6 0.1 0.00061 19.4 0.1 1.1 1 0 0 1 1 1 1 Ras family PDZ PF00595.24 KFM82764.1 - 6.3e-30 103.4 1.9 8.2e-15 54.9 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFM82764.1 - 5.1e-17 61.5 0.0 3.5e-08 33.2 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFM82764.1 - 1.8e-07 31.4 0.0 0.0071 16.6 0.0 3.3 3 0 0 3 3 3 2 PDZ domain FBPase PF00316.20 KFM82765.1 - 1.6e-75 252.8 0.0 2e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KFM82765.1 - 0.0004 20.0 0.0 0.00063 19.3 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Nrap_D4 PF17405.2 KFM82766.1 - 1.7e-45 155.0 0.0 2.5e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KFM82766.1 - 6.1e-41 139.9 0.0 9.5e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 KFM82766.1 - 1.8e-30 106.1 0.0 3.7e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KFM82766.1 - 1.4e-27 96.5 0.0 2.5e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap PF03813.14 KFM82767.1 - 1.9e-34 118.9 0.2 2.9e-34 118.3 0.2 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 KFM82767.1 - 2e-32 112.1 0.4 3e-32 111.5 0.4 1.3 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain SecM PF06558.12 KFM82769.1 - 1.4 9.1 5.2 1.1 9.4 1.3 2.3 1 1 0 2 2 2 0 Secretion monitor precursor protein (SecM) GAS PF13851.6 KFM82769.1 - 6.7 6.0 54.7 0.047 13.1 4.0 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding GRIP PF01465.20 KFM82770.1 - 2.6e-07 30.4 0.0 5.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 GRIP domain BBP1_C PF15272.6 KFM82770.1 - 0.00063 19.6 9.8 0.0074 16.1 3.1 2.1 2 0 0 2 2 2 2 Spindle pole body component BBP1, C-terminal NYD-SP28 PF14772.6 KFM82770.1 - 0.022 14.8 1.9 0.022 14.8 1.9 3.1 2 1 1 3 3 3 0 Sperm tail TFA2_Winged_2 PF18121.1 KFM82770.1 - 0.15 11.8 2.6 2.5 7.9 0.1 2.9 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 PKcGMP_CC PF16808.5 KFM82770.1 - 0.22 11.4 11.6 4.9 7.1 0.5 4.2 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1690 PF07956.11 KFM82770.1 - 1.7 9.0 11.6 0.094 13.1 4.3 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Methyltransf_28 PF02636.17 KFM82771.1 - 1.2e-63 215.2 0.0 3.1e-63 213.9 0.0 1.6 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Peptidase_A22B PF04258.13 KFM82772.1 - 1.5e-18 67.3 4.5 1.7e-18 67.1 4.5 1.0 1 0 0 1 1 1 1 Signal peptide peptidase TMEM208_SND2 PF05620.11 KFM82772.1 - 0.026 14.3 1.1 0.031 14.1 1.1 1.4 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF4519 PF15012.6 KFM82772.1 - 1 9.6 0.0 1 9.6 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Peptidase_A22B PF04258.13 KFM82773.1 - 5.7e-42 144.2 1.3 6.2e-42 144.1 1.3 1.0 1 0 0 1 1 1 1 Signal peptide peptidase MMR_HSR1 PF01926.23 KFM82774.1 - 2.8e-20 72.5 0.3 5.2e-20 71.6 0.3 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM82774.1 - 3.7e-08 33.0 0.1 1.1e-07 31.5 0.2 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFM82774.1 - 1.4e-07 31.2 0.4 4e-05 23.2 0.4 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM82774.1 - 2.8e-07 30.6 0.8 6.9e-05 22.8 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KFM82774.1 - 1.6e-05 24.4 0.6 2.2e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KFM82774.1 - 5.4e-05 23.3 0.2 0.39 10.8 0.1 2.5 1 1 1 2 2 2 2 Dynamin family PduV-EutP PF10662.9 KFM82774.1 - 0.00016 21.4 0.1 0.2 11.4 0.1 2.7 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KFM82774.1 - 0.00027 21.1 0.8 0.00058 20.1 0.1 2.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM82774.1 - 0.001 18.7 0.4 0.0066 16.1 0.4 2.1 1 1 0 1 1 1 1 Ras family Septin PF00735.18 KFM82774.1 - 0.026 13.8 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Septin Ocular_alb PF02101.15 KFM82777.1 - 2.9e-52 178.0 20.1 5e-52 177.2 20.1 1.3 1 1 0 1 1 1 1 Ocular albinism type 1 protein Dicty_CAR PF05462.11 KFM82777.1 - 0.0012 18.0 20.8 0.0043 16.2 18.6 2.1 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 KFM82777.1 - 0.021 14.1 11.9 0.03 13.6 11.9 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (Secretin family) Sulfotransfer_2 PF03567.14 KFM82779.1 - 6.9e-64 216.2 3.3 1.1e-63 215.6 3.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF2534 PF10749.9 KFM82779.1 - 0.065 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) SNF2_N PF00176.23 KFM82780.1 - 1e-73 248.1 1.2 1e-73 248.1 1.2 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KFM82780.1 - 1.8e-21 76.0 0.2 8e-21 73.9 0.2 2.0 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 KFM82780.1 - 8.2e-21 74.4 0.0 6.4e-19 68.3 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 KFM82780.1 - 1.6e-20 73.2 14.7 1.6e-20 73.2 14.7 3.2 2 0 0 2 2 2 1 HSA BRK PF07533.16 KFM82780.1 - 1e-19 69.9 0.0 2.3e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 BRK domain SnAC PF14619.6 KFM82780.1 - 3.4e-19 69.2 8.1 3.4e-19 69.2 8.1 4.8 5 1 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KFM82780.1 - 4e-12 45.7 3.6 4e-12 45.7 3.6 2.5 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 KFM82780.1 - 1.2e-10 41.6 0.0 1.2e-10 41.6 0.0 3.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM82780.1 - 4.5e-05 23.3 0.0 4.5e-05 23.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF3246 PF11596.8 KFM82780.1 - 0.055 12.9 1.9 0.1 12.0 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Rad9 PF04139.13 KFM82781.1 - 5.9e-70 235.6 2.9 9.9e-70 234.8 2.9 1.3 1 0 0 1 1 1 1 Rad9 PCNA_N PF00705.18 KFM82781.1 - 6.3e-05 22.7 0.1 0.013 15.2 0.1 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, N-terminal domain DUF3246 PF11596.8 KFM82781.1 - 0.0069 15.9 1.8 0.011 15.2 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) SpoIIE PF07228.12 KFM82782.1 - 2.3e-12 47.3 0.0 3.7e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KFM82782.1 - 1.6e-08 34.5 0.0 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KFM82782.1 - 3.9e-08 33.2 0.2 7.7e-07 29.0 0.2 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L2_C PF03947.18 KFM82783.1 - 3.2e-46 156.6 4.5 5e-46 156.0 4.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFM82783.1 - 1.3e-19 69.9 1.2 2.4e-19 69.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain wnt PF00110.19 KFM82784.1 - 4.5e-120 400.9 22.9 5.1e-120 400.7 22.9 1.0 1 0 0 1 1 1 1 wnt family Chordopox_A13L PF05961.11 KFM82785.1 - 0.015 15.5 3.7 0.03 14.6 0.8 2.4 1 1 1 2 2 2 0 Chordopoxvirus A13L protein Cid2 PF09774.9 KFM82785.1 - 0.031 14.7 6.1 0.075 13.5 6.1 1.6 1 1 0 1 1 1 0 Caffeine-induced death protein 2 Polysacc_deac_1 PF01522.21 KFM82786.1 - 2e-10 40.6 0.1 3.7e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_4 PF00379.23 KFM82787.1 - 7.5e-10 39.2 2.7 1.7e-09 38.1 2.7 1.6 1 0 0 1 1 1 1 Insect cuticle protein Chitin_bind_4 PF00379.23 KFM82788.1 - 1.1e-08 35.4 0.4 2.2e-08 34.5 0.4 1.5 1 0 0 1 1 1 1 Insect cuticle protein HLH PF00010.26 KFM82789.1 - 1.4e-11 44.2 0.2 9.9e-11 41.4 0.1 2.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PRY PF13765.6 KFM82789.1 - 0.033 13.8 0.0 0.094 12.4 0.0 1.8 1 0 0 1 1 1 0 SPRY-associated domain TSC22 PF01166.18 KFM82789.1 - 0.036 14.4 0.4 0.13 12.6 0.4 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family ZapB PF06005.12 KFM82789.1 - 1.9 9.0 8.2 4.6 7.8 1.1 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Sulfatase PF00884.23 KFM82792.1 - 6.2e-70 236.0 0.3 8.1e-70 235.7 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFM82792.1 - 1.2e-07 31.6 0.9 5e-07 29.6 0.9 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KFM82792.1 - 0.002 18.8 0.0 0.39 11.5 0.0 2.4 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KFM82792.1 - 0.0023 17.8 0.1 0.028 14.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function Sulfatase PF00884.23 KFM82793.1 - 2.8e-53 181.3 0.0 9.6e-41 140.2 0.0 2.1 1 1 1 2 2 2 2 Sulfatase Sulfatase_C PF14707.6 KFM82793.1 - 0.0022 18.8 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KFM82793.1 - 0.0041 17.0 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function Sulfatase PF00884.23 KFM82794.1 - 2.1e-65 221.2 0.0 2.8e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFM82794.1 - 0.00012 21.8 0.2 0.00074 19.2 0.2 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFM82794.1 - 0.00021 20.1 0.1 0.16 10.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF229) DUF4994 PF16385.5 KFM82794.1 - 0.017 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Sulfatase_C PF14707.6 KFM82794.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Nudc_N PF14050.6 KFM82794.1 - 0.16 11.9 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. EF-hand_1 PF00036.32 KFM82795.1 - 3.7e-27 91.8 11.0 6.7e-07 28.4 0.2 5.5 5 1 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KFM82795.1 - 8.6e-27 93.4 2.5 6.3e-12 45.8 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM82795.1 - 4.9e-25 85.3 5.1 6.8e-07 28.7 0.2 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 KFM82795.1 - 3.4e-21 74.8 0.9 6e-12 45.2 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFM82795.1 - 2.4e-15 55.2 5.5 7.9e-06 25.1 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KFM82795.1 - 3.7e-06 27.2 0.1 0.36 11.2 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_4 PF12763.7 KFM82795.1 - 0.00045 20.1 0.1 0.00097 19.1 0.1 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Kinesin PF00225.23 KFM82796.1 - 1.1e-117 392.7 0.0 1.5e-117 392.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM82796.1 - 2.3e-26 92.5 0.0 4.4e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_30 PF13604.6 KFM82796.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KFM82796.1 - 0.039 13.1 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase Ntox22 PF15527.6 KFM82796.1 - 0.041 13.9 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Bacterial toxin 22 Pox_A_type_inc PF04508.12 KFM82796.1 - 0.074 12.9 0.3 0.22 11.5 0.3 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat BST2 PF16716.5 KFM82796.1 - 0.51 11.0 0.1 0.51 11.0 0.1 2.2 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 AAA_11 PF13086.6 KFM82796.1 - 2.7 7.7 8.5 0.93 9.2 5.4 1.8 2 0 0 2 2 2 0 AAA domain A1_Propeptide PF07966.12 KFM82797.1 - 6 6.8 7.2 1 9.3 0.3 2.8 3 0 0 3 3 3 0 A1 Propeptide LAMTOR PF15454.6 KFM82798.1 - 5.7e-09 36.5 4.7 2.7e-08 34.3 1.3 2.4 2 0 0 2 2 2 2 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Peptidase_M13_N PF05649.13 KFM82803.1 - 2.4e-110 369.8 0.5 7.4e-109 364.9 0.2 2.1 2 0 0 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.21 KFM82803.1 - 8.9e-74 247.5 0.2 1.7e-73 246.6 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M13 Fibrinogen_C PF00147.18 KFM82804.1 - 6.9e-71 238.6 11.6 8.4e-71 238.3 11.6 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 KFM82805.1 - 8e-64 215.5 13.4 9e-64 215.3 13.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain ChitinaseA_N PF08329.10 KFM82805.1 - 0.073 12.7 1.3 0.086 12.5 0.4 1.6 1 1 1 2 2 2 0 Chitinase A, N-terminal domain 7tm_7 PF08395.12 KFM82806.1 - 0.017 14.4 0.1 0.021 14.1 0.1 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor SARAF PF06682.12 KFM82806.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CrgA PF06781.12 KFM82806.1 - 0.17 11.9 0.6 0.3 11.1 0.3 1.7 1 1 0 1 1 1 0 Cell division protein CrgA Ank_2 PF12796.7 KFM82807.1 - 5.1e-45 152.0 2.9 1.3e-17 64.2 0.7 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFM82807.1 - 2.7e-32 109.8 0.7 1.7e-05 25.1 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KFM82807.1 - 3.9e-31 103.6 0.1 5.1e-06 26.4 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 KFM82807.1 - 6.5e-29 99.9 0.2 2.1e-11 44.1 0.1 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM82807.1 - 5.3e-26 90.3 2.1 3e-08 33.7 0.3 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) ScdA_N PF04405.14 KFM82807.1 - 0.02 14.6 0.2 0.66 9.7 0.2 2.7 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) Ribosomal_S6 PF01250.17 KFM82807.1 - 0.022 15.0 0.0 2 8.8 0.0 2.7 2 1 1 3 3 3 0 Ribosomal protein S6 TF_AP-2 PF03299.14 KFM82807.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AP-2 DUF3454 PF11936.8 KFM82808.1 - 0.52 10.8 4.0 5 7.6 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) ELO PF01151.18 KFM82810.1 - 4.2e-51 173.9 25.3 4.9e-51 173.7 25.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PspC PF04024.12 KFM82810.1 - 1.1 9.1 4.9 0.33 10.8 0.3 2.5 2 1 0 2 2 2 0 PspC domain Synaptobrevin PF00957.21 KFM82810.1 - 4 7.3 5.5 2.9 7.7 1.5 2.3 2 0 0 2 2 2 0 Synaptobrevin Mucin PF01456.17 KFM82811.1 - 0.84 9.6 2.3 0.74 9.8 2.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-C2H2 PF00096.26 KFM82812.1 - 0.0099 16.3 1.4 1.7 9.2 0.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFM82812.1 - 0.015 15.1 1.6 0.017 14.9 0.5 1.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFM82812.1 - 0.044 14.2 0.2 0.055 13.9 0.2 1.2 1 0 0 1 1 1 0 Zinc-finger double domain Clostridium_P47 PF06597.11 KFM82812.1 - 0.089 11.5 0.0 0.089 11.5 0.0 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein Retrotran_gag_2 PF14223.6 KFM82813.1 - 0.0022 17.7 0.1 0.0029 17.3 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 KFM82814.1 - 1e-11 45.0 0.0 1.2e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KFM82814.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RNA_pol_L_2 PF13656.6 KFM82814.1 - 0.11 12.3 0.1 0.29 10.9 0.1 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain RVT_2 PF07727.14 KFM82815.1 - 3.6e-05 23.5 0.3 3.6e-05 23.5 0.3 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) U62_UL91 PF17442.2 KFM82815.1 - 0.11 12.5 0.4 0.11 12.5 0.4 1.5 2 0 0 2 2 2 0 Functional domain of U62 and UL91 proteins SOCS_box PF07525.16 KFM82819.1 - 9.2e-10 38.7 0.1 1.3e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 SOCS box Grp7_allergen PF16984.5 KFM82821.1 - 1.1e-33 116.8 0.0 1.5e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Group 7 allergen DUF963 PF06131.11 KFM82821.1 - 0.021 14.2 3.4 7.8 6.0 0.1 3.0 1 1 4 5 5 5 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Grp7_allergen PF16984.5 KFM82822.1 - 4.9e-31 108.2 0.1 5.6e-31 108.0 0.1 1.0 1 0 0 1 1 1 1 Group 7 allergen Grp7_allergen PF16984.5 KFM82824.1 - 2.5e-31 109.1 0.0 3e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Group 7 allergen Grp7_allergen PF16984.5 KFM82825.1 - 9e-20 71.5 0.0 1.1e-19 71.2 0.0 1.1 1 0 0 1 1 1 1 Group 7 allergen JHBP PF06585.11 KFM82826.1 - 9.6e-36 123.1 2.3 1.2e-35 122.9 2.3 1.1 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) TIG PF01833.24 KFM82828.1 - 1.6e-13 50.5 0.3 1.9e-13 50.3 0.3 1.1 1 0 0 1 1 1 1 IPT/TIG domain COE1_DBD PF16422.5 KFM82828.1 - 0.0075 15.7 0.5 0.01 15.3 0.5 1.2 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain SH2 PF00017.24 KFM82829.1 - 5.5e-17 61.6 0.2 2.4e-16 59.6 0.1 2.1 2 0 0 2 2 2 1 SH2 domain BPS PF08947.10 KFM82829.1 - 1.7e-12 47.0 0.0 1.8e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 BPS (Between PH and SH2) RA PF00788.23 KFM82829.1 - 5e-08 33.5 0.4 6.6e-07 29.9 0.1 2.7 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFM82829.1 - 9.4e-08 32.5 1.4 2.7e-07 31.0 1.4 1.8 1 0 0 1 1 1 1 PH domain PIP5K PF01504.18 KFM82830.1 - 1.6e-56 191.5 0.1 7.6e-56 189.3 0.1 2.0 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase zf-CDGSH PF09360.10 KFM82831.1 - 1.1e-09 38.3 0.3 1.3e-09 38.1 0.3 1.2 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type TED_complement PF07678.14 KFM82832.1 - 1.3e-14 53.9 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 A-macroglobulin TED domain SoxY PF13501.6 KFM82832.1 - 0.14 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY SH3_1 PF00018.28 KFM82835.1 - 4e-14 52.0 0.0 6.6e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFM82835.1 - 7.7e-13 48.1 0.0 1.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFM82835.1 - 0.00087 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ABC_membrane PF00664.23 KFM82837.1 - 8.1e-10 38.8 3.0 8.1e-10 38.8 3.0 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region HAD_2 PF13419.6 KFM82839.1 - 1.1e-25 90.8 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM82839.1 - 5.2e-13 49.8 0.0 1.3e-09 38.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM82839.1 - 2e-09 37.3 0.0 3.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KFM82839.1 - 0.0012 18.6 0.0 0.69 9.7 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase HAD PF12710.7 KFM82839.1 - 0.0032 17.9 0.0 0.01 16.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.12 KFM82839.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF705) PGP_phosphatase PF09419.10 KFM82839.1 - 0.027 14.1 0.2 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase EntA_Immun PF08951.10 KFM82839.1 - 0.19 12.1 0.1 0.55 10.6 0.0 1.8 2 0 0 2 2 2 0 Enterocin A Immunity HHH_5 PF14520.6 KFM82840.1 - 2.1e-07 31.4 0.6 4.9e-07 30.3 0.4 1.6 1 1 1 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 KFM82840.1 - 0.0081 16.0 0.2 0.019 14.8 0.1 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_11 PF08279.12 KFM82840.1 - 0.1 12.6 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 HTH domain Rad51 PF08423.11 KFM82841.1 - 2.4e-128 426.8 0.1 2.6e-128 426.6 0.1 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFM82841.1 - 6.1e-11 42.3 0.0 7.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFM82841.1 - 2.7e-10 40.2 0.1 5.1e-10 39.3 0.1 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KFM82841.1 - 6.7e-07 28.9 0.4 1.7e-06 27.6 0.4 1.7 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KFM82841.1 - 0.0032 16.8 0.3 0.52 9.6 0.3 2.6 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KFM82841.1 - 0.007 16.6 0.1 0.016 15.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFM82841.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 KFM82841.1 - 0.031 13.4 0.3 0.076 12.1 0.1 1.6 2 0 0 2 2 2 0 PAXNEB protein ssDNA_TraI_N PF18272.1 KFM82841.1 - 0.1 12.6 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain BACK PF07707.15 KFM82844.1 - 2.7e-05 24.2 0.1 3.9e-05 23.7 0.1 1.3 1 1 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFM82845.1 - 2.1e-22 79.5 1.8 3.1e-19 69.2 0.0 3.2 2 2 1 3 3 3 3 BTB/POZ domain BACK PF07707.15 KFM82845.1 - 0.063 13.4 1.2 1.4 9.0 0.1 2.5 3 0 0 3 3 3 0 BTB And C-terminal Kelch Kelch_1 PF01344.25 KFM82846.1 - 4.8e-25 86.9 3.2 7.7e-07 28.6 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KFM82846.1 - 6.4e-24 83.5 1.1 5.3e-08 32.7 0.1 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 KFM82846.1 - 1.2e-23 82.8 2.1 1.8e-06 28.1 0.0 4.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KFM82846.1 - 5.1e-23 80.8 4.0 1.9e-07 31.0 0.1 4.3 2 1 2 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM82846.1 - 2.3e-22 78.5 2.0 6.7e-07 29.4 0.1 4.2 3 1 1 4 4 4 4 Kelch motif Kelch_2 PF07646.15 KFM82846.1 - 3.5e-13 49.0 11.1 2.9e-05 23.9 0.3 4.5 5 1 0 5 5 5 3 Kelch motif CN_hydrolase PF00795.22 KFM82847.1 - 3.2e-13 49.6 0.0 4.8e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_C14 PF00656.22 KFM82848.1 - 1.3e-47 162.8 0.3 1.6e-47 162.6 0.3 1.0 1 0 0 1 1 1 1 Caspase domain Fibrinogen_C PF00147.18 KFM82849.1 - 1.5e-63 214.6 11.9 1.9e-63 214.3 11.9 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain COLFI PF01410.18 KFM82849.1 - 0.0075 15.6 0.6 0.012 14.9 0.5 1.5 1 1 0 1 1 1 1 Fibrillar collagen C-terminal domain Peptidase_C14 PF00656.22 KFM82850.1 - 9.6e-36 124.0 2.2 7.5e-29 101.4 0.7 3.0 2 1 0 2 2 2 2 Caspase domain Peptidase_C14 PF00656.22 KFM82851.1 - 4.7e-45 154.5 0.3 5.4e-45 154.3 0.3 1.0 1 0 0 1 1 1 1 Caspase domain Fibrinogen_C PF00147.18 KFM82852.1 - 7.9e-63 212.2 10.2 9.5e-63 211.9 10.2 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain COLFI PF01410.18 KFM82852.1 - 0.0052 16.1 0.5 0.011 15.0 0.5 1.6 1 1 0 1 1 1 1 Fibrillar collagen C-terminal domain ELFV_dehydrog_N PF02812.18 KFM82853.1 - 1.9e-55 186.3 0.0 3.6e-55 185.4 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 KFM82853.1 - 8.3e-49 166.5 0.0 1.9e-46 158.8 0.0 2.2 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Stork_head PF10264.9 KFM82854.1 - 6.3e-30 103.2 0.0 1.5e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain RFamide_26RFa PF11109.8 KFM82854.1 - 0.12 12.9 0.2 0.2 12.2 0.2 1.3 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 Apolipoprotein PF01442.18 KFM82860.1 - 5.3e-05 23.2 0.1 6.1e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KFM82860.1 - 8.1e-05 23.1 4.9 0.1 13.2 4.9 2.4 1 1 0 1 1 1 1 YtxH-like protein ApoLp-III PF07464.11 KFM82860.1 - 0.00023 21.3 3.3 0.0015 18.6 2.2 2.0 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Retrotrans_gag PF03732.17 KFM82860.1 - 0.0031 17.8 1.3 0.11 12.7 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein SF-assemblin PF06705.11 KFM82860.1 - 0.0036 16.7 4.5 0.0043 16.4 4.5 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin Lipoprotein_2 PF00921.17 KFM82860.1 - 0.0038 16.8 4.8 0.005 16.5 4.8 1.2 1 0 0 1 1 1 1 Borrelia lipoprotein DUF3437 PF11919.8 KFM82860.1 - 0.0041 17.0 2.2 0.092 12.7 0.3 2.6 1 1 2 3 3 3 1 Domain of unknown function (DUF3437) Phage_GPO PF05929.11 KFM82860.1 - 0.0043 16.7 1.3 0.0047 16.6 1.3 1.2 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase FlgN PF05130.12 KFM82860.1 - 0.014 16.0 0.9 0.027 15.0 0.5 1.6 2 0 0 2 2 2 0 FlgN protein Gp-FAR-1 PF05823.12 KFM82860.1 - 0.02 15.2 4.4 0.027 14.8 4.4 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) OmpH PF03938.14 KFM82860.1 - 0.024 15.0 6.5 0.031 14.6 6.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Apo-CIII PF05778.12 KFM82860.1 - 0.028 14.0 0.7 2.4 7.8 0.1 2.3 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) DUF883 PF05957.13 KFM82860.1 - 0.029 15.0 0.2 1.6 9.3 0.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Bac_rhamnosid6H PF17389.2 KFM82860.1 - 0.043 13.1 1.7 0.053 12.8 1.7 1.0 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4533 PF15047.6 KFM82860.1 - 0.052 13.1 3.0 0.047 13.2 1.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4533) DUF1664 PF07889.12 KFM82860.1 - 0.081 13.0 1.9 0.28 11.2 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF624 PF04854.14 KFM82860.1 - 0.09 12.9 1.4 11 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF624 IL32 PF15225.6 KFM82860.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 Interleukin 32 Prefoldin PF02996.17 KFM82860.1 - 0.19 11.6 6.7 0.77 9.7 0.2 2.5 2 1 1 3 3 3 0 Prefoldin subunit HEPN_AbiU2 PF18734.1 KFM82860.1 - 1.9 8.0 10.9 4.3 6.8 10.9 1.6 1 1 0 1 1 1 0 AbiU2 Tsc35 PF15079.6 KFM82860.1 - 2.1 7.9 11.3 0.58 9.7 0.9 2.2 1 1 1 2 2 2 0 Testis-specific protein 35 TCTP PF00838.17 KFM82860.1 - 3.6 7.9 10.8 6.7 7.0 2.6 2.7 1 1 2 3 3 3 0 Translationally controlled tumour protein Band_7 PF01145.25 KFM82861.1 - 9.9e-12 45.2 2.8 1.2e-11 44.9 2.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFM82861.1 - 5.6e-05 22.9 0.0 7.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 KFM82861.1 - 0.019 15.3 2.1 0.043 14.2 0.8 2.1 1 1 1 2 2 2 0 Phage protein Gp68 23S_rRNA_IVP PF05635.11 KFM82861.1 - 0.12 12.7 1.7 0.18 12.1 1.2 1.4 1 1 0 1 1 1 0 23S rRNA-intervening sequence protein PGDYG PF14083.6 KFM82861.1 - 0.15 12.3 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 PGDYG protein Bestrophin PF01062.21 KFM82862.1 - 3.7e-51 174.3 1.2 4.1e-51 174.1 1.2 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel p450 PF00067.22 KFM82863.1 - 1.6e-84 284.3 0.1 2e-84 284.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 F_bP_aldolase PF01116.20 KFM82864.1 - 0.21 11.0 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II EF-hand_1 PF00036.32 KFM82866.1 - 4.8e-43 141.5 10.8 5.9e-10 38.0 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFM82866.1 - 2.6e-36 123.9 2.7 1.6e-18 66.9 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFM82866.1 - 1.7e-33 114.3 11.2 8.6e-16 57.5 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFM82866.1 - 1.2e-30 102.7 6.0 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFM82866.1 - 1.5e-27 93.8 8.3 7.4e-07 28.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFM82866.1 - 7.7e-16 58.2 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFM82866.1 - 1.7e-10 40.7 0.4 4.2e-05 23.4 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFM82866.1 - 6.3e-08 32.9 0.0 0.0064 16.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KFM82866.1 - 1.3e-06 29.2 0.0 0.00052 20.8 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFM82866.1 - 1.4e-05 25.0 0.0 0.042 13.9 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFM82866.1 - 7.1e-05 22.8 0.7 0.0005 20.1 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KFM82866.1 - 0.00022 21.4 4.2 0.055 13.7 0.4 3.1 1 1 1 2 2 2 2 Dockerin type I domain DUF1103 PF06513.11 KFM82866.1 - 0.00048 19.8 1.9 0.00052 19.7 1.9 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 KFM82866.1 - 0.0011 19.7 0.4 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 KFM82866.1 - 0.0016 18.4 0.9 0.53 10.2 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KFM82866.1 - 0.0027 18.0 0.6 1.6 9.1 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 KFM82866.1 - 0.0028 18.1 0.0 1.4 9.4 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 KFM82866.1 - 0.0039 17.1 0.6 0.49 10.4 0.1 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF5580 PF17743.1 KFM82866.1 - 0.01 14.4 0.0 0.01 14.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Poly_export PF02563.16 KFM82866.1 - 0.013 15.8 0.0 0.95 9.7 0.0 3.0 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 KFM82866.1 - 0.015 15.2 0.6 0.9 9.4 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 KFM82866.1 - 0.021 15.0 0.4 0.38 10.9 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KFM82866.1 - 0.025 13.8 0.1 2.2 7.4 0.0 2.3 1 1 0 2 2 2 0 Cache domain DUF2267 PF10025.9 KFM82866.1 - 0.033 14.5 0.0 0.15 12.4 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Fe_hyd_lg_C PF02906.14 KFM82866.1 - 0.044 13.4 0.7 0.18 11.4 0.7 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 KFM82866.1 - 0.067 13.5 0.1 9.2 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain TetR_C_7 PF14246.6 KFM82866.1 - 0.081 13.0 0.1 7.8 6.6 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Spore_III_AB PF09548.10 KFM82866.1 - 0.12 12.5 0.3 0.24 11.5 0.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RuvA_C PF07499.13 KFM82866.1 - 0.14 12.6 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain CMD PF02627.20 KFM82866.1 - 0.17 12.0 0.3 7.3 6.7 0.0 2.8 3 1 0 3 3 3 0 Carboxymuconolactone decarboxylase family SapB_1 PF05184.15 KFM82866.1 - 0.23 11.5 1.2 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 LLGL PF08366.13 KFM82867.1 - 6.3e-36 122.9 0.0 3e-35 120.7 0.0 2.2 2 0 0 2 2 2 1 LLGL2 ANAPC4_WD40 PF12894.7 KFM82867.1 - 7.4e-06 26.2 0.8 1.4 9.3 0.0 5.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM82867.1 - 6e-05 23.7 11.9 0.13 13.1 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat zf-H2C2_2 PF13465.6 KFM82869.1 - 3.1e-84 274.0 87.3 5.3e-10 39.3 0.1 12.7 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM82869.1 - 6.4e-56 183.8 119.3 3.1e-05 24.2 4.4 12.6 13 0 0 13 13 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM82869.1 - 3.7e-40 133.1 108.5 0.00043 20.9 2.9 13.1 13 0 0 13 13 13 12 C2H2-type zinc finger zf-met PF12874.7 KFM82869.1 - 1e-21 76.6 101.7 0.0011 19.3 0.5 12.7 13 0 0 13 13 12 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM82869.1 - 2.7e-20 72.1 71.8 0.028 14.7 0.2 12.4 12 0 0 12 12 12 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM82869.1 - 1e-19 70.0 82.4 0.011 15.7 1.1 13.1 13 0 0 13 13 12 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM82869.1 - 2.7e-13 49.4 84.5 0.008 15.9 2.0 12.8 13 0 0 13 13 13 7 C2H2-type zinc-finger domain BolA PF01722.18 KFM82869.1 - 2.9e-07 30.6 27.3 0.18 12.1 0.1 8.4 1 1 4 7 7 7 3 BolA-like protein zf-C2HC_2 PF13913.6 KFM82869.1 - 6.8e-06 25.9 48.9 0.044 13.7 0.0 11.5 11 1 1 12 12 12 2 zinc-finger of a C2HC-type Baculo_IE-1 PF05290.11 KFM82869.1 - 0.00027 20.9 35.1 0.48 10.4 0.1 7.4 1 1 6 7 7 7 3 Baculovirus immediate-early protein (IE-0) BHD_1 PF10403.9 KFM82869.1 - 0.00041 20.1 2.4 4.6 7.2 0.1 5.0 4 1 1 5 5 5 1 Rad4 beta-hairpin domain 1 zf-MYST PF17772.1 KFM82869.1 - 0.0058 16.2 59.3 0.12 12.1 0.9 11.1 7 2 5 12 12 12 3 MYST family zinc finger domain C1_1 PF00130.22 KFM82869.1 - 0.035 14.0 68.9 1.3 9.0 1.7 10.2 4 3 6 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 KFM82869.1 - 0.042 13.6 0.7 0.042 13.6 0.7 10.7 12 0 0 12 12 12 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFM82869.1 - 0.092 13.5 42.9 3.7 8.4 1.1 6.3 1 1 3 6 6 6 0 zinc-ribbon family DUF3396 PF11876.8 KFM82869.1 - 0.12 11.8 0.0 1.2 8.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3396) zf-Paramyx-P PF13008.7 KFM82869.1 - 0.17 11.4 0.1 0.17 11.4 0.1 6.7 8 1 1 9 9 8 0 Zinc-binding domain of Paramyxoviridae V protein Rad50_zn_hook PF04423.14 KFM82869.1 - 0.29 11.0 0.1 0.29 11.0 0.1 4.0 4 1 0 4 4 4 0 Rad50 zinc hook motif DUF5330 PF17264.2 KFM82869.1 - 1.5 8.9 7.7 21 5.2 0.0 5.1 6 0 0 6 6 6 0 Family of unknown function (DUF5330) YyzF PF14116.6 KFM82869.1 - 1.7 8.7 37.2 18 5.5 0.3 10.6 11 1 1 12 12 12 0 YyzF-like protein FYVE PF01363.21 KFM82869.1 - 2.4 8.4 70.9 6.3e+02 0.6 14.7 7.4 2 2 1 3 3 2 0 FYVE zinc finger zf-CHCC PF10276.9 KFM82869.1 - 2.5 8.2 26.0 10 6.3 0.0 9.5 12 0 0 12 12 12 0 Zinc-finger domain Scramblase PF03803.15 KFM82869.1 - 6 6.1 8.0 4.7 6.4 0.2 3.2 1 1 2 3 3 3 0 Scramblase zf_UBZ PF18439.1 KFM82869.1 - 7.1 6.3 48.6 12 5.6 0.6 11.1 12 0 0 12 12 12 0 Ubiquitin-Binding Zinc Finger zf-RRPl_C4 PF17026.5 KFM82869.1 - 7.1 6.8 40.1 0.86 9.7 5.6 5.3 1 1 5 6 6 6 0 Putative ribonucleoprotein zinc-finger pf C4 type ADK_lid PF05191.14 KFM82869.1 - 8.7 6.4 37.7 0.39 10.7 0.4 7.0 3 2 3 7 7 7 0 Adenylate kinase, active site lid Peptidase_C13 PF01650.18 KFM82870.1 - 6.4e-113 376.5 0.6 9.7e-113 375.9 0.1 1.5 2 0 0 2 2 2 1 Peptidase C13 family Peptidase_C14 PF00656.22 KFM82870.1 - 0.028 14.4 0.2 0.058 13.3 0.0 1.6 2 0 0 2 2 2 0 Caspase domain MRJP PF03022.16 KFM82870.1 - 0.042 13.2 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 Major royal jelly protein Zn-C2H2_12 PF18112.1 KFM82871.1 - 0.1 13.1 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain tRNA-synt_1 PF00133.22 KFM82873.1 - 2.2e-109 366.4 0.2 2.7e-109 366.1 0.2 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KFM82873.1 - 3.1e-06 26.8 0.0 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KFM82873.1 - 7.9e-06 24.9 1.1 0.00013 20.8 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) EpoR_lig-bind PF09067.10 KFM82873.1 - 0.0098 16.1 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding Herpes_US9 PF06072.11 KFM82875.1 - 0.34 10.8 3.1 0.85 9.5 3.1 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF2116 PF09889.9 KFM82875.1 - 0.66 10.0 1.8 2.2 8.3 1.8 1.9 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NodZ PF05830.11 KFM82876.1 - 0.2 10.4 0.3 0.19 10.5 0.3 1.0 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Form_Nir_trans PF01226.17 KFM82879.1 - 0.034 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Formate/nitrite transporter CTC1 PF15489.6 KFM82880.1 - 1.4e-06 26.2 1.6 1.7e-06 25.9 1.6 1.0 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 SF3a60_bindingd PF12108.8 KFM82880.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain CDC24_OB3 PF17244.2 KFM82880.1 - 1.9 8.1 10.0 0.079 12.7 2.5 2.0 1 1 1 2 2 2 0 Cell division control protein 24, OB domain 3 Na_H_Exchanger PF00999.21 KFM82881.1 - 7.4e-22 77.7 35.8 7.4e-22 77.7 35.8 2.6 1 1 2 3 3 3 2 Sodium/hydrogen exchanger family Wzy_C PF04932.15 KFM82881.1 - 0.021 14.5 0.4 0.021 14.5 0.4 3.7 3 2 0 3 3 3 0 O-Antigen ligase Glyco_hydro_18 PF00704.28 KFM82882.1 - 0.0043 16.8 0.1 0.0054 16.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BTB PF00651.31 KFM82883.1 - 2.7e-20 72.7 0.8 3.7e-20 72.2 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFM82883.1 - 1.7e-06 28.0 1.4 4.1e-05 23.6 0.5 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch BACK PF07707.15 KFM82884.1 - 5.1e-16 58.6 17.3 5.4e-09 36.1 6.0 3.3 3 0 0 3 3 3 2 BTB And C-terminal Kelch BTB PF00651.31 KFM82884.1 - 3.8e-10 40.0 9.9 6e-05 23.2 0.4 4.6 2 2 2 4 4 4 3 BTB/POZ domain Peptidase_M28 PF04389.17 KFM82888.1 - 3e-39 134.8 0.0 4.3e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFM82888.1 - 0.0039 16.9 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KFM82888.1 - 0.021 13.8 0.0 0.037 13.1 0.0 1.5 1 1 0 1 1 1 0 M42 glutamyl aminopeptidase ELO PF01151.18 KFM82890.1 - 1.3e-42 146.1 17.6 1.5e-42 145.9 17.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Sm_multidrug_ex PF06695.11 KFM82890.1 - 0.039 14.6 0.9 0.082 13.6 0.1 1.9 2 0 0 2 2 2 0 Putative small multi-drug export protein ANF_receptor PF01094.28 KFM82891.1 - 9.6e-52 176.2 0.1 1.2e-51 175.9 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KFM82891.1 - 1e-05 25.4 0.0 0.00025 20.8 0.0 2.0 2 0 0 2 2 2 2 Periplasmic binding protein Aldo_ket_red PF00248.21 KFM82892.1 - 2.3e-14 53.3 0.1 2.3e-14 53.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KFM82893.1 - 5.2e-24 84.9 0.0 5.9e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_M17 PF00883.21 KFM82894.1 - 1.9e-64 217.9 0.1 2.3e-64 217.7 0.1 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pup_ligase PF03136.15 KFM82895.1 - 0.037 13.1 0.1 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 Pup-ligase protein BLOC1_2 PF10046.9 KFM82895.1 - 0.12 12.6 6.9 0.054 13.8 3.6 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MPS2 PF17060.5 KFM82895.1 - 0.13 11.5 8.0 0.16 11.2 8.0 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 Nup88 PF10168.9 KFM82895.1 - 0.25 9.1 8.4 0.28 8.9 8.4 1.0 1 0 0 1 1 1 0 Nuclear pore component FapA PF03961.13 KFM82895.1 - 0.36 9.4 5.9 0.38 9.3 5.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mvb12 PF09452.10 KFM82895.1 - 0.43 11.0 4.3 2.6 8.5 0.5 2.2 1 1 0 2 2 2 0 ESCRT-I subunit Mvb12 Spc24 PF08286.11 KFM82895.1 - 1.1 9.6 8.3 8.1 6.8 8.3 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 KFM82895.1 - 1.7 8.5 5.8 1.1 9.0 3.7 1.7 2 0 0 2 2 2 0 Septum formation initiator Sec20 PF03908.13 KFM82895.1 - 4.7 7.2 7.5 6.1 6.8 0.4 2.1 1 1 1 2 2 2 0 Sec20 zf-C2H2 PF00096.26 KFM82896.1 - 9e-18 63.7 24.4 1.9e-05 24.8 0.5 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM82896.1 - 1.7e-16 59.8 20.8 1.3e-07 31.7 0.3 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM82896.1 - 4.3e-12 45.8 20.7 0.023 15.5 0.3 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM82896.1 - 0.0041 17.4 12.8 0.17 12.2 0.6 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Transpos_assoc PF13963.6 KFM82896.1 - 0.01 16.1 6.2 0.12 12.8 0.2 2.9 2 1 1 3 3 3 0 Transposase-associated domain zf-C2H2_aberr PF17017.5 KFM82896.1 - 0.013 15.7 8.0 3.7 7.6 0.2 3.2 1 1 2 4 4 4 0 Aberrant zinc-finger Raffinose_syn PF05691.12 KFM82896.1 - 0.025 12.4 0.0 0.035 11.9 0.0 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 IBR PF01485.21 KFM82896.1 - 0.029 14.6 1.8 0.029 14.6 1.8 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain MAM PF00629.23 KFM82896.1 - 0.048 13.6 0.1 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 MAM domain, meprin/A5/mu zf-met PF12874.7 KFM82896.1 - 0.081 13.3 7.8 1.1 9.7 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFM82896.1 - 0.17 11.7 6.3 3.4 7.5 0.4 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 KFM82896.1 - 0.19 12.0 5.6 2.1 8.7 0.1 3.6 4 0 0 4 4 3 0 zinc-ribbon zf_UBZ PF18439.1 KFM82896.1 - 0.28 10.8 4.9 2.9 7.5 0.2 3.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-CGNR PF11706.8 KFM82896.1 - 0.35 10.8 7.3 6.1 6.8 0.7 3.4 3 1 0 3 3 3 0 CGNR zinc finger CCAP PF11105.8 KFM82896.1 - 0.7 9.8 3.2 3.9 7.4 3.1 2.1 1 1 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a XPA_N PF01286.18 KFM82896.1 - 1 9.5 7.1 2.9 8.0 0.1 3.0 4 0 0 4 4 4 0 XPA protein N-terminal CHORD PF04968.12 KFM82896.1 - 1.8 9.3 11.9 6.9 7.5 2.3 3.5 1 1 3 4 4 4 0 CHORD zf-TRAF PF02176.18 KFM82896.1 - 2.3 9.0 13.2 7.4 7.3 3.7 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger Sod_Cu PF00080.20 KFM82897.1 - 2.3e-51 173.7 4.1 2.9e-51 173.4 4.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) eIF-1a PF01176.19 KFM82898.1 - 9.4e-22 76.6 0.1 1.3e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Acyl_transf_3 PF01757.22 KFM82899.1 - 8.8e-20 71.0 22.2 8.8e-20 71.0 22.2 1.5 2 0 0 2 2 2 1 Acyltransferase family DUF1624 PF07786.12 KFM82902.1 - 0.0025 17.4 1.4 0.0038 16.8 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) CENP-X PF09415.10 KFM82903.1 - 6.4e-19 68.0 0.1 7.3e-19 67.9 0.1 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 KFM82903.1 - 0.0095 16.2 1.1 0.016 15.5 1.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IFN-gamma PF00714.17 KFM82903.1 - 0.047 13.5 0.0 0.055 13.3 0.0 1.1 1 0 0 1 1 1 0 Interferon gamma Acyl_transf_3 PF01757.22 KFM82905.1 - 0.059 12.4 6.6 0.067 12.2 6.6 1.1 1 0 0 1 1 1 0 Acyltransferase family EVC2_like PF12297.8 KFM82905.1 - 0.36 9.5 0.8 0.41 9.3 0.8 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Laminin_G_2 PF02210.24 KFM82907.1 - 1.5e-23 83.7 0.9 2.5e-23 83.0 0.9 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFM82907.1 - 8.7e-13 48.6 0.2 1.5e-12 47.9 0.2 1.4 1 0 0 1 1 1 1 Laminin G domain Protocadherin PF08374.11 KFM82907.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Laminin_G_3 PF13385.6 KFM82907.1 - 0.067 13.3 0.3 0.14 12.3 0.3 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Syndecan PF01034.20 KFM82907.1 - 0.32 10.9 7.0 0.79 9.7 7.0 1.6 1 1 0 1 1 1 0 Syndecan domain Flp1_like PF16982.5 KFM82907.1 - 4.3 6.8 8.0 7.6 6.0 8.0 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain SRP-alpha_N PF04086.13 KFM82908.1 - 5e-57 194.0 18.5 8.4e-57 193.3 18.6 1.3 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KFM82908.1 - 1e-48 165.6 0.3 3.5e-48 163.9 0.3 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KFM82908.1 - 1.5e-08 34.7 0.0 6.6e-08 32.7 0.0 2.2 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KFM82908.1 - 2.1e-05 23.7 0.0 0.00013 21.1 0.0 2.0 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KFM82908.1 - 0.00024 20.8 0.0 0.13 12.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain CbiA PF01656.23 KFM82908.1 - 0.00039 20.5 0.0 0.0027 17.8 0.0 2.4 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KFM82908.1 - 0.0061 16.9 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KFM82908.1 - 0.0063 15.6 1.2 0.054 12.5 0.2 2.6 2 1 1 3 3 3 1 Type II/IV secretion system protein NTPase_1 PF03266.15 KFM82908.1 - 0.0067 16.4 0.7 0.065 13.1 0.1 2.7 2 1 0 2 2 2 1 NTPase ArsA_ATPase PF02374.15 KFM82908.1 - 0.011 14.9 0.0 0.078 12.1 0.0 2.3 2 0 0 2 2 2 0 Anion-transporting ATPase Fer4_NifH PF00142.18 KFM82908.1 - 0.018 14.5 0.1 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 KFM82908.1 - 0.024 14.6 0.4 0.97 9.3 0.0 3.2 2 1 1 3 3 3 0 RsgA GTPase AAA_30 PF13604.6 KFM82908.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM82908.1 - 0.096 13.0 0.0 0.32 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain GIT_CC PF16559.5 KFM82909.1 - 0.0063 16.4 2.5 0.0063 16.4 2.5 5.6 4 2 1 5 5 5 3 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 KFM82909.1 - 0.2 11.0 84.6 0.011 15.1 31.9 4.7 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding GTP_EFTU PF00009.27 KFM82910.1 - 6.9e-65 218.2 0.0 1.4e-64 217.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFM82910.1 - 7.9e-33 112.8 0.0 1.8e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KFM82910.1 - 2.5e-29 101.2 0.0 4.3e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFM82910.1 - 1.9e-27 95.1 0.0 5.8e-27 93.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFM82910.1 - 9.7e-16 57.9 0.0 3.4e-15 56.2 0.0 2.0 2 0 0 2 2 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFM82910.1 - 8.4e-07 28.9 0.0 2.3e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 KFM82910.1 - 6.5e-05 23.3 0.0 0.0042 17.5 0.0 3.1 3 0 0 3 3 3 1 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 KFM82910.1 - 0.00015 21.8 0.1 0.0003 20.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFM82910.1 - 0.005 16.2 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KFM82910.1 - 0.055 13.0 0.1 0.2 11.1 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KFM82910.1 - 0.11 11.9 0.0 0.45 9.9 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_L29e PF01779.17 KFM82911.1 - 2e-22 79.2 10.9 2e-22 79.2 10.9 1.8 2 0 0 2 2 2 1 Ribosomal L29e protein family Coilin_N PF15862.5 KFM82912.1 - 3.8e-07 30.0 8.4 3.8e-07 30.0 8.4 3.6 3 1 0 3 3 3 2 Coilin N-terminus DHHC PF01529.20 KFM82913.1 - 8.2e-35 119.8 15.4 1.1e-34 119.4 15.4 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase zinc_ribbon_2 PF13240.6 KFM82913.1 - 0.041 13.6 3.1 0.086 12.6 3.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Spt4 PF06093.13 KFM82913.1 - 0.042 13.9 4.1 0.072 13.2 4.1 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger RecR PF02132.15 KFM82913.1 - 0.4 10.3 10.0 0.36 10.4 7.0 2.1 1 1 1 2 2 2 0 RecR protein DZR PF12773.7 KFM82913.1 - 3.6 7.7 8.5 5.9 7.0 8.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon YlaC PF10777.9 KFM82914.1 - 0.048 13.5 6.4 0.051 13.4 6.4 1.0 1 0 0 1 1 1 0 Inner membrane protein YlaC GCV_T PF01571.21 KFM82915.1 - 5.2e-86 288.2 0.0 6.3e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KFM82915.1 - 7.2e-17 61.1 0.0 5.3e-16 58.3 0.0 2.1 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Ion_trans PF00520.31 KFM82916.1 - 8.8e-09 34.9 1.2 1e-08 34.7 1.2 1.1 1 0 0 1 1 1 1 Ion transport protein Baculo_11_kDa PF06143.11 KFM82916.1 - 0.036 13.6 0.6 0.049 13.2 0.6 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family PKD_channel PF08016.12 KFM82916.1 - 0.13 10.9 4.5 0.16 10.6 4.5 1.1 1 0 0 1 1 1 0 Polycystin cation channel LAP1C PF05609.12 KFM82916.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Protamine_like PF06382.11 KFM82917.1 - 0.01 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Protamine and protamine like PNP_UDP_1 PF01048.20 KFM82918.1 - 3.2e-12 46.2 0.0 3.8e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily HCMV_UL124 PF17609.2 KFM82918.1 - 0.14 12.4 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function AAA_12 PF13087.6 KFM82919.1 - 3.9e-36 124.5 0.0 7.6e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM82919.1 - 2.2e-25 89.9 1.6 6.2e-14 52.4 0.0 3.4 3 1 0 4 4 4 2 AAA domain AAA_30 PF13604.6 KFM82919.1 - 1e-09 38.4 0.0 7e-09 35.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFM82919.1 - 2.1e-06 28.1 0.0 1.4e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KFM82919.1 - 2.5e-05 24.4 0.0 0.00013 22.0 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFM82919.1 - 0.00031 20.3 0.0 0.52 9.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.21 KFM82919.1 - 0.0069 15.9 0.0 0.073 12.6 0.0 2.4 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain zf-C2H2_jaz PF12171.8 KFM82919.1 - 0.0071 16.6 0.8 0.036 14.3 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PAM2 PF07145.15 KFM82919.1 - 0.0081 15.8 0.6 0.022 14.4 0.6 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region UvrD_C_2 PF13538.6 KFM82919.1 - 0.033 14.0 0.2 0.094 12.6 0.2 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF4570 PF15134.6 KFM82919.1 - 0.13 12.3 0.5 3.2 7.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) zf-CCCH PF00642.24 KFM82919.1 - 6 6.9 13.3 0.012 15.5 2.8 2.2 2 0 0 2 2 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Neur_chan_memb PF02932.16 KFM82920.1 - 9e-24 84.8 5.8 5.3e-21 75.8 3.7 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region COX1 PF00115.20 KFM82920.1 - 0.011 14.6 2.4 0.013 14.4 2.4 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I NPA PF16469.5 KFM82920.1 - 0.18 12.4 0.0 0.24 12.0 0.0 1.1 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 adh_short PF00106.25 KFM82921.1 - 1.2e-37 129.3 0.3 1.4e-37 129.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM82921.1 - 2.9e-27 95.7 0.1 3.6e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM82921.1 - 8.9e-14 51.8 0.1 1.1e-13 51.4 0.1 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KFM82921.1 - 0.0058 16.0 0.1 0.0099 15.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFM82921.1 - 0.013 14.7 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KFM82921.1 - 0.023 15.4 0.1 0.12 13.1 0.1 1.9 1 1 1 2 2 2 0 Methyltransferase domain NAD_binding_7 PF13241.6 KFM82921.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding FtsJ PF01728.19 KFM82922.1 - 6.4e-70 234.8 0.0 7.9e-70 234.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase TIL PF01826.17 KFM82924.1 - 1.5e-14 54.0 27.5 5.2e-11 42.6 18.8 2.3 2 0 0 2 2 2 2 Trypsin Inhibitor like cysteine rich domain EGF_2 PF07974.13 KFM82924.1 - 0.0097 16.3 17.6 0.021 15.2 6.6 3.0 3 0 0 3 3 3 2 EGF-like domain FOG_N PF15888.5 KFM82924.1 - 0.029 14.7 1.4 0.069 13.5 1.4 1.6 1 0 0 1 1 1 0 Folded gastrulation N-terminus Tme5_EGF_like PF09064.10 KFM82924.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.2 2 1 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like LptF_LptG PF03739.14 KFM82924.1 - 0.59 8.9 1.6 0.64 8.8 1.6 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG GBR2_CC PF18455.1 KFM82926.1 - 0.012 15.7 0.8 0.053 13.6 0.8 2.2 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain DUF5104 PF17117.5 KFM82926.1 - 0.025 15.0 0.2 0.089 13.2 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) DUF4250 PF14056.6 KFM82926.1 - 0.057 13.4 1.5 1.3 9.1 0.3 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4250) ELMO_CED12 PF04727.13 KFM82927.1 - 1.9e-40 138.9 0.2 3.7e-40 137.9 0.0 1.5 2 0 0 2 2 2 1 ELMO/CED-12 family Head-tail_con PF12236.8 KFM82927.1 - 0.16 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein DUF4371 PF14291.6 KFM82928.1 - 5.3e-05 23.0 0.1 6.2e-05 22.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Fasciclin PF02469.22 KFM82930.1 - 2.7e-111 367.1 5.6 6.6e-30 104.0 0.0 4.0 4 0 0 4 4 4 4 Fasciclin domain DUF1967 PF09269.11 KFM82930.1 - 0.044 13.7 0.2 6.5 6.8 0.0 3.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1967) VP9 PF09625.10 KFM82930.1 - 0.053 13.7 0.1 0.24 11.6 0.2 2.0 2 0 0 2 2 2 0 VP9 protein Chlor_dismutase PF06778.12 KFM82930.1 - 0.074 12.6 0.2 2.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Chlorite dismutase Spc24 PF08286.11 KFM82930.1 - 0.076 13.3 0.3 0.076 13.3 0.3 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FHA PF00498.26 KFM82930.1 - 0.11 12.8 1.3 11 6.5 0.2 2.9 2 0 0 2 2 2 0 FHA domain 7TM-7TMR_HD PF07698.11 KFM82932.1 - 0.0043 16.8 0.1 0.0055 16.5 0.1 1.1 1 0 0 1 1 1 1 7TM receptor with intracellular HD hydrolase Herpes_US9 PF06072.11 KFM82932.1 - 0.079 12.8 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Tetraspanin PF00335.20 KFM82932.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF3087 PF11286.8 KFM82932.1 - 0.15 11.5 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF3357 PF11837.8 KFM82932.1 - 0.16 12.5 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) UQ_con PF00179.26 KFM82933.1 - 2.1e-40 137.6 0.1 2.5e-40 137.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM82933.1 - 0.057 13.7 0.2 0.089 13.1 0.2 1.5 1 1 0 1 1 1 0 RWD domain GMC_oxred_C PF05199.13 KFM82935.1 - 5.3e-17 62.7 0.3 8.8e-17 62.0 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KFM82936.1 - 1.3e-26 93.6 0.0 1.5e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFM82936.1 - 0.043 12.9 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain SAM_2 PF07647.17 KFM82937.1 - 1.2e-29 102.2 1.0 1.1e-11 44.7 0.0 3.5 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFM82937.1 - 2.4e-29 101.6 2.6 1.8e-11 44.3 0.2 3.6 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) cwf21 PF08312.12 KFM82937.1 - 0.26 11.5 2.4 0.77 10.0 2.4 1.8 1 0 0 1 1 1 0 cwf21 domain THAP PF05485.12 KFM82940.1 - 4e-16 59.7 3.2 7e-16 58.9 3.2 1.4 1 0 0 1 1 1 1 THAP domain Sterile PF03015.19 KFM82941.1 - 2e-25 88.9 1.2 2.2e-25 88.7 1.2 1.0 1 0 0 1 1 1 1 Male sterility protein NAD_binding_4 PF07993.12 KFM82942.1 - 4.3e-17 62.1 0.0 4.6e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Male sterility protein DinI PF06183.13 KFM82942.1 - 0.0047 17.2 0.0 0.0062 16.8 0.0 1.3 1 0 0 1 1 1 1 DinI-like family NAD_binding_4 PF07993.12 KFM82943.1 - 3.5e-66 223.0 0.0 4.4e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 KFM82943.1 - 2.6e-13 50.0 1.0 5.6e-13 48.9 1.0 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KFM82943.1 - 1.1e-06 28.3 0.0 1.2e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFM82943.1 - 0.002 18.5 0.0 0.0044 17.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KFM82943.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFM82943.1 - 0.037 13.2 0.1 0.081 12.0 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein E1_dh PF00676.20 KFM82944.1 - 4.4e-98 327.9 0.0 4.9e-98 327.8 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFM82944.1 - 2.7e-05 24.0 0.0 6.3e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 KFM82944.1 - 4.9e-05 22.4 0.0 6.7e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 KFM82944.1 - 8.9e-05 21.8 0.0 0.00034 19.9 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Adeno_hexon_C PF03678.14 KFM82944.1 - 0.036 13.5 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, C-terminal domain Cyclin_C PF02984.19 KFM82946.1 - 0.033 14.3 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain MMR_HSR1 PF01926.23 KFM82948.1 - 2.4e-05 24.4 0.1 3.6e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KFM82948.1 - 0.021 14.6 0.6 0.064 12.9 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFM82948.1 - 0.06 13.2 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 KFM82948.1 - 0.062 13.1 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM82948.1 - 0.22 11.3 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GCR1_C PF12550.8 KFM82951.1 - 0.16 12.3 0.9 0.25 11.7 0.9 1.3 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes RNA_pol_A_CTD PF03118.15 KFM82953.1 - 4.4e-05 23.2 7.7 48 3.8 0.0 7.8 2 2 6 8 8 8 4 Bacterial RNA polymerase, alpha chain C terminal domain DHHW PF14286.6 KFM82953.1 - 0.044 13.1 0.1 0.07 12.4 0.1 1.2 1 0 0 1 1 1 0 DHHW protein AMP-binding PF00501.28 KFM82954.1 - 1.5e-22 79.8 0.0 1.9e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM82954.1 - 0.11 13.5 0.0 0.19 12.7 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFM82955.1 - 2.9e-31 108.5 0.0 3.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM82955.1 - 8.4e-10 38.4 1.6 1.8e-09 37.4 1.6 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Rho_RNA_bind PF07497.12 KFM82955.1 - 0.0025 17.6 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 Rho termination factor, RNA-binding domain AMP-binding PF00501.28 KFM82956.1 - 9.6e-51 172.7 0.0 1.1e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFM82956.1 - 3.5e-11 42.8 1.7 7.8e-11 41.7 1.7 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PAPS_reduct PF01507.19 KFM82956.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Rho_RNA_bind PF07497.12 KFM82956.1 - 0.18 11.7 0.0 0.58 10.1 0.0 1.8 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain AMP-binding_C PF13193.6 KFM82957.1 - 0.0053 17.7 0.0 0.0078 17.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain baeRF_family12 PF18856.1 KFM82957.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 AMP-binding PF00501.28 KFM82958.1 - 6.8e-17 61.2 0.0 7.2e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Rho_RNA_bind PF07497.12 KFM82958.1 - 0.003 17.4 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain DUF2110 PF09883.9 KFM82958.1 - 0.0049 16.5 0.0 0.0056 16.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2110) TfuA PF07812.12 KFM82958.1 - 0.089 12.5 0.7 1.9 8.2 0.1 2.1 1 1 1 2 2 2 0 TfuA-like protein AMP-binding PF00501.28 KFM82959.1 - 6.2e-05 21.8 0.0 6.2e-05 21.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF4518 PF15008.6 KFM82961.1 - 2.5e-06 26.9 0.0 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4518) zf-H2C2_2 PF13465.6 KFM82962.1 - 1.9e-72 236.7 112.1 1.8e-07 31.2 1.2 16.1 16 0 0 16 16 16 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM82962.1 - 1.6e-48 160.5 145.0 0.00071 19.9 2.3 16.1 17 0 0 17 17 17 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM82962.1 - 1.4e-44 146.9 132.5 0.0031 18.2 2.1 15.6 15 0 0 15 15 15 15 C2H2-type zinc finger zf-met PF12874.7 KFM82962.1 - 4e-25 87.4 112.5 0.00036 20.8 5.0 15.6 16 0 0 16 16 16 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM82962.1 - 2.2e-21 75.6 103.3 0.056 13.8 0.5 16.0 14 2 2 16 16 16 13 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM82962.1 - 1.1e-09 38.0 99.4 0.34 11.0 0.3 15.4 15 0 0 15 15 15 9 C2H2-type zinc finger BolA PF01722.18 KFM82962.1 - 0.008 16.4 28.8 7.2 7.0 0.4 9.1 4 3 4 8 8 8 2 BolA-like protein Trypan_PARP PF05887.11 KFM82962.1 - 0.13 12.3 12.7 0.29 11.1 12.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GAGA PF09237.11 KFM82962.1 - 1.4 8.8 33.6 6.1 6.7 0.0 8.6 3 3 7 10 10 10 0 GAGA factor Ribosomal_L11_N PF03946.14 KFM82963.1 - 4.5e-24 84.1 0.2 6.7e-24 83.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KFM82963.1 - 7.4e-16 58.4 0.1 1.3e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain RRM_1 PF00076.22 KFM82964.1 - 3.7e-28 97.1 1.4 5.6e-13 48.5 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM82964.1 - 1.8e-09 37.2 0.3 3.7e-05 23.3 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM82964.1 - 2.8e-05 23.9 0.0 0.33 10.8 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 KFM82964.1 - 0.00028 20.7 0.0 0.00091 19.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) SARAF PF06682.12 KFM82964.1 - 0.15 11.7 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Argos PF11581.8 KFM82966.1 - 3.1e-44 150.1 8.7 3.1e-44 150.1 8.7 2.0 2 0 0 2 2 2 1 Antagonist of EGFR signalling, Argos CART PF06373.11 KFM82966.1 - 0.12 12.5 4.1 0.92 9.7 0.4 2.8 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) DUF2613 PF11021.8 KFM82966.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) SH2 PF00017.24 KFM82969.1 - 3.6e-35 119.9 0.0 1.7e-17 63.3 0.1 2.7 2 0 0 2 2 2 2 SH2 domain PI3K_P85_iSH2 PF16454.5 KFM82969.1 - 1.3e-21 76.8 6.1 2.6e-21 75.9 6.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain RhoGAP PF00620.27 KFM82969.1 - 0.0059 16.4 0.1 0.017 15.0 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain Colicin_E5 PF12106.8 KFM82969.1 - 0.029 14.6 0.1 0.17 12.2 0.1 2.2 1 1 0 1 1 1 0 Colicin E5 ribonuclease domain TMF_TATA_bd PF12325.8 KFM82969.1 - 0.24 11.6 3.8 0.59 10.4 0.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2046 PF09755.9 KFM82970.1 - 0.0027 17.0 12.3 0.0035 16.6 12.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Cnn_1N PF07989.11 KFM82970.1 - 0.0033 17.5 13.5 0.39 10.9 5.4 2.3 1 1 1 2 2 2 2 Centrosomin N-terminal motif 1 Apolipoprotein PF01442.18 KFM82970.1 - 0.013 15.4 5.4 0.021 14.7 5.4 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain zf-RING_9 PF13901.6 KFM82970.1 - 0.022 14.8 1.0 0.023 14.7 1.0 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Spc24 PF08286.11 KFM82970.1 - 0.025 14.8 10.7 0.055 13.7 4.8 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.6 KFM82970.1 - 0.034 14.6 6.1 0.092 13.2 1.9 2.2 2 0 0 2 2 2 0 Snapin/Pallidin CENP-F_leu_zip PF10473.9 KFM82970.1 - 0.041 13.9 16.3 0.31 11.1 5.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 KFM82970.1 - 0.074 12.9 8.7 0.062 13.2 3.3 2.7 1 1 2 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Csd3_N PF18059.1 KFM82970.1 - 0.075 13.6 1.9 4.9 7.7 0.1 2.2 1 1 1 2 2 2 0 Csd3 N-terminal APG6_N PF17675.1 KFM82970.1 - 0.14 12.7 17.6 1.1 9.8 7.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KFM82970.1 - 0.65 10.1 15.4 0.96 9.5 13.7 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TPH PF13868.6 KFM82970.1 - 0.9 8.0 20.2 1.2 7.6 20.2 1.1 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain DUF4349 PF14257.6 KFM82970.1 - 0.94 8.9 4.0 0.28 10.6 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) FapA PF03961.13 KFM82970.1 - 0.94 8.0 10.0 1.2 7.6 10.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A PRKG1_interact PF15898.5 KFM82970.1 - 1.4 9.9 16.3 1 10.3 3.3 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 KFM82970.1 - 1.4 9.6 12.9 1.2e+02 3.4 12.9 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Ax_dynein_light PF10211.9 KFM82970.1 - 1.8 8.5 18.3 2 8.3 4.1 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4140 PF13600.6 KFM82970.1 - 2.7 8.5 7.2 13 6.3 0.3 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2205 PF10224.9 KFM82970.1 - 3.9 7.5 9.9 0.4 10.7 3.1 2.2 1 1 0 2 2 2 0 Short coiled-coil protein TolA_bind_tri PF16331.5 KFM82970.1 - 3.9 7.6 11.1 1.7 8.8 5.6 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation FlaC_arch PF05377.11 KFM82970.1 - 4 7.9 9.4 2.8 8.4 0.5 2.9 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 KFM82970.1 - 4 6.9 9.5 4.5 6.8 9.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 KFM82970.1 - 5.4 6.2 9.7 7 5.8 9.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 KFM82970.1 - 5.6 5.7 6.7 6.2 5.6 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0242 PF06785.11 KFM82970.1 - 6.6 6.8 14.7 9.9 6.2 14.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CHD5 PF04420.14 KFM82970.1 - 7.1 6.5 9.6 4.2 7.2 3.2 2.2 1 1 1 2 2 2 0 CHD5-like protein Uso1_p115_C PF04871.13 KFM82970.1 - 7.4 7.0 14.3 2.1e+02 2.2 14.3 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-H PF05837.12 KFM82970.1 - 9.3 6.7 14.8 40 4.7 1.3 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) p450 PF00067.22 KFM82972.1 - 3e-91 306.5 0.6 7.1e-89 298.7 0.6 2.0 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L9_C PF03948.14 KFM82972.1 - 0.0081 16.6 0.2 0.38 11.2 0.0 2.7 3 0 0 3 3 3 1 Ribosomal protein L9, C-terminal domain p450 PF00067.22 KFM82973.1 - 1.3e-89 301.0 1.7 3.1e-87 293.3 1.7 2.0 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L9_C PF03948.14 KFM82973.1 - 0.0074 16.7 0.1 0.54 10.7 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain p450 PF00067.22 KFM82974.1 - 4.6e-91 305.9 1.0 3e-64 217.5 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 Ribosomal_L9_C PF03948.14 KFM82974.1 - 0.021 15.3 0.1 4.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain p450 PF00067.22 KFM82975.1 - 1.1e-92 311.2 0.4 2.5e-64 217.8 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 TrkA_TMD PF18613.1 KFM82975.1 - 1.3 8.5 4.6 2.3 7.7 4.6 1.4 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain DZF PF07528.14 KFM82977.1 - 6.8e-94 314.1 0.0 1e-93 313.5 0.0 1.2 1 0 0 1 1 1 1 DZF domain SMODS PF18144.1 KFM82977.1 - 0.065 13.4 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DUF4371 PF14291.6 KFM82979.1 - 0.0017 18.0 0.1 0.0031 17.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) zf-C2H2_12 PF18658.1 KFM82979.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type Stc1 PF12898.7 KFM82979.1 - 0.11 13.1 1.5 0.19 12.3 0.1 2.1 2 1 2 4 4 4 0 Stc1 domain C1_1 PF00130.22 KFM82980.1 - 1.6e-28 98.4 52.9 2.5e-12 46.5 7.4 3.4 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) RA PF00788.23 KFM82980.1 - 4.6e-22 78.5 0.0 1.4e-09 38.5 0.0 2.4 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C1_2 PF03107.16 KFM82980.1 - 0.0032 17.7 42.5 0.013 15.7 7.5 4.2 3 1 1 4 4 4 2 C1 domain TUG-UBL1 PF11470.8 KFM82980.1 - 0.0037 17.5 0.0 0.75 10.1 0.0 2.8 3 0 0 3 3 3 1 TUG ubiquitin-like domain YusW PF14039.6 KFM82980.1 - 0.023 15.2 0.0 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 YusW-like protein PHD PF00628.29 KFM82980.1 - 3.3 7.7 45.1 0.2 11.6 12.1 3.8 3 0 0 3 3 3 0 PHD-finger wnt PF00110.19 KFM82982.1 - 2.2e-14 53.8 0.4 2.8e-14 53.4 0.4 1.1 1 0 0 1 1 1 1 wnt family tRNA-synt_1 PF00133.22 KFM82983.1 - 2.1e-209 696.8 0.0 2.7e-208 693.1 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFM82983.1 - 3e-37 127.9 0.0 6.9e-37 126.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KFM82983.1 - 6.4e-14 51.9 0.1 1.1e-10 41.3 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KFM82983.1 - 9.4e-12 44.4 0.1 0.00059 18.7 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 KFM82983.1 - 3.9e-07 30.3 2.5 1.2e-06 28.7 2.5 1.9 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm Jag_N PF14804.6 KFM82983.1 - 0.0051 17.1 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Jag N-terminus tRNA-synt_1e PF01406.19 KFM82983.1 - 0.013 14.9 0.0 0.047 13.0 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 KFM82983.1 - 0.18 11.1 0.4 0.6 9.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Snapin_Pallidin PF14712.6 KFM82983.1 - 0.7 10.4 7.9 0.084 13.3 2.3 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Gln-synt_C PF00120.24 KFM82985.1 - 6.1e-16 58.3 0.0 9.1e-14 51.2 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFM82985.1 - 8.8e-11 41.4 0.0 1.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain adh_short PF00106.25 KFM82986.1 - 6.3e-52 175.9 0.1 7.8e-52 175.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM82986.1 - 6.3e-36 124.1 0.0 8.7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM82986.1 - 1e-12 48.3 0.1 1.5e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KFM82986.1 - 0.0062 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KFM82986.1 - 0.048 13.1 0.1 0.072 12.5 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KFM82986.1 - 0.14 12.0 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Homeodomain PF00046.29 KFM82987.1 - 8.8e-09 35.1 3.0 1.4e-08 34.4 3.0 1.4 1 0 0 1 1 1 1 Homeodomain GTP_EFTU PF00009.27 KFM82989.1 - 3.7e-16 59.2 0.0 4e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM82989.1 - 0.085 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase GTP_EFTU_D2 PF03144.25 KFM82990.1 - 3.3e-06 27.4 0.0 1.5e-05 25.2 0.0 2.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KFM82990.1 - 0.0089 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain HLH PF00010.26 KFM82991.1 - 1.7e-16 59.9 1.3 2.7e-16 59.2 1.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SpoU_methylase PF00588.19 KFM82996.1 - 1.2e-26 93.5 0.0 1.5e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family zf-H2C2_2 PF13465.6 KFM82997.1 - 5e-14 52.0 11.9 3.3e-06 27.3 0.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM82997.1 - 1.8e-13 50.1 16.2 2.5e-05 24.5 1.0 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM82997.1 - 1.4e-12 47.3 16.1 9.6e-05 22.9 0.9 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFM82997.1 - 2.5e-06 27.7 3.0 2.5e-06 27.7 3.0 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFM82997.1 - 0.00021 21.5 15.7 0.024 14.9 0.4 3.3 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-RING_2 PF13639.6 KFM82997.1 - 0.00034 20.9 2.5 4.1 7.8 0.1 3.2 3 0 0 3 3 3 1 Ring finger domain zf-met PF12874.7 KFM82997.1 - 0.0009 19.6 15.3 0.49 10.9 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-RING_5 PF14634.6 KFM82997.1 - 0.0014 18.6 7.1 1.5 8.9 0.7 3.2 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM82997.1 - 0.0018 18.1 3.4 3.4 7.6 0.1 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM82997.1 - 0.006 16.4 3.2 3 7.8 0.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_2 PF12756.7 KFM82997.1 - 0.0067 16.7 10.0 1.6 9.1 0.1 3.0 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KFM82997.1 - 0.015 14.9 6.6 0.74 9.5 0.7 2.9 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2H2_9 PF16293.5 KFM82997.1 - 0.016 15.0 7.4 1.1 9.1 0.1 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM82997.1 - 0.021 14.6 2.4 15 5.5 0.1 3.1 1 1 2 3 3 3 0 GAGA factor zf-RING_UBOX PF13445.6 KFM82997.1 - 0.024 14.7 3.3 3.2 7.8 0.1 3.2 3 0 0 3 3 3 0 RING-type zinc-finger Zn-C2H2_12 PF18112.1 KFM82997.1 - 0.031 14.7 0.6 0.031 14.7 0.6 3.6 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Zn_Tnp_IS1595 PF12760.7 KFM82997.1 - 0.031 14.2 4.0 0.18 11.8 0.6 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain LIM PF00412.22 KFM82997.1 - 0.045 14.0 4.7 3.9 7.8 0.5 2.9 3 0 0 3 3 3 0 LIM domain BolA PF01722.18 KFM82997.1 - 0.21 11.9 2.5 2.5 8.4 1.2 2.2 1 1 1 2 2 2 0 BolA-like protein Rad50_zn_hook PF04423.14 KFM82997.1 - 0.24 11.3 2.1 9 6.2 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 KFM82997.1 - 0.26 11.2 4.7 9.5 6.2 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2HE PF16278.5 KFM82997.1 - 0.29 11.6 8.8 15 6.1 0.0 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 KFM82997.1 - 0.36 11.2 7.6 0.59 10.5 0.9 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-TFIIB PF13453.6 KFM82997.1 - 0.71 9.3 3.4 2.3 7.6 0.0 2.3 2 1 0 2 2 2 0 Transcription factor zinc-finger NADH-G_4Fe-4S_3 PF10588.9 KFM82997.1 - 0.72 9.4 3.0 47 3.6 0.0 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Vps36-NZF-N PF16988.5 KFM82997.1 - 0.82 9.1 5.2 13 5.3 3.2 2.5 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-LITAF-like PF10601.9 KFM82997.1 - 0.96 9.8 9.4 22 5.4 9.4 2.7 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain zf-H2C2_5 PF13909.6 KFM82997.1 - 1.8 8.4 0.0 1.8 8.4 0.0 3.9 3 2 0 3 3 2 0 C2H2-type zinc-finger domain zf-WRNIP1_ubi PF18279.1 KFM82997.1 - 5.9 7.8 14.2 1.1 10.0 2.5 3.5 3 2 0 3 3 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain UBZ_FAAP20 PF15750.5 KFM82997.1 - 7.9 6.5 6.5 41 4.2 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger DUF2256 PF10013.9 KFM82997.1 - 8.2 6.6 7.7 14 5.9 0.3 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Tim44 PF04280.15 KFM82998.1 - 2.5e-44 150.9 0.1 1.3e-43 148.7 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain Pullulanase_Ins PF18494.1 KFM82998.1 - 0.2 12.1 0.6 21 5.6 0.0 2.9 3 0 0 3 3 3 0 Pullulanase Ins domain CHCH PF06747.13 KFM83001.1 - 0.045 13.9 0.7 1.8 8.8 0.0 2.7 2 1 0 2 2 2 0 CHCH domain MRFAP1 PF15155.6 KFM83002.1 - 0.5 10.9 6.2 0.11 13.1 0.7 2.6 2 0 0 2 2 2 0 MORF4 family-associated protein1 ARF7EP_C PF14949.6 KFM83004.1 - 2.1e-14 54.0 24.9 2.1e-14 54.0 24.9 2.2 2 1 1 3 3 3 1 ARF7 effector protein C-terminus Ribosomal_L38e PF01781.18 KFM83004.1 - 8.7 6.5 13.9 0.058 13.5 3.6 2.4 3 0 0 3 3 3 0 Ribosomal L38e protein family MOSC PF03473.17 KFM83006.1 - 3.4e-13 49.8 0.0 3.9e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 MOSC domain MOSC PF03473.17 KFM83007.1 - 0.0073 16.3 0.0 0.0082 16.2 0.0 1.1 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KFM83008.1 - 1.2e-24 86.5 0.0 2.1e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KFM83008.1 - 8.7e-21 74.3 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KFM83009.1 - 1.5e-25 89.4 0.0 2.3e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KFM83009.1 - 1.4e-20 73.6 0.0 2.5e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 MOSC domain RNase_H PF00075.24 KFM83010.1 - 0.00042 20.5 0.0 0.00067 19.9 0.0 1.3 1 0 0 1 1 1 1 RNase H Tektin PF03148.14 KFM83011.1 - 2.3e-103 345.9 40.8 2.5e-103 345.8 40.8 1.0 1 0 0 1 1 1 1 Tektin family PspA_IM30 PF04012.12 KFM83011.1 - 0.0085 15.7 23.4 0.1 12.2 1.2 3.4 3 0 0 3 3 3 2 PspA/IM30 family ADIP PF11559.8 KFM83011.1 - 0.024 14.7 4.3 0.024 14.7 4.3 4.0 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding GCN5L1 PF06320.13 KFM83011.1 - 0.026 14.6 3.3 0.026 14.6 3.3 3.4 4 1 0 4 4 4 0 GCN5-like protein 1 (GCN5L1) FAM76 PF16046.5 KFM83011.1 - 0.04 13.3 21.6 0.045 13.1 1.6 3.2 2 1 1 3 3 3 0 FAM76 protein DUF4376 PF14301.6 KFM83011.1 - 0.048 14.0 0.5 0.048 14.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) ATG16 PF08614.11 KFM83011.1 - 0.061 13.6 30.2 0.22 11.8 1.5 4.3 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 KFM83011.1 - 0.14 12.2 16.1 2.1 8.4 3.4 3.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4140 PF13600.6 KFM83011.1 - 0.62 10.5 18.4 0.96 9.9 1.7 3.9 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) BORCS8 PF10167.9 KFM83011.1 - 0.65 10.0 0.1 0.65 10.0 0.1 3.3 3 1 0 3 3 3 0 BLOC-1-related complex sub-unit 8 DUF4200 PF13863.6 KFM83011.1 - 1.1 9.7 29.1 1.3 9.5 9.3 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 KFM83011.1 - 1.5 7.6 31.7 0.078 11.8 0.4 3.4 3 1 0 3 3 3 0 Spc7 kinetochore protein DUF1192 PF06698.11 KFM83011.1 - 2.5 8.2 18.1 2.6 8.2 1.1 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) DASH_Dam1 PF08653.10 KFM83011.1 - 4.2 7.2 4.4 1e+02 2.8 0.0 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 Cep57_MT_bd PF06657.13 KFM83011.1 - 5.1 7.6 20.3 0.5 10.9 1.3 4.2 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 ATP_synth_reg PF14960.6 KFM83012.1 - 4.8e-21 74.0 0.7 5.4e-21 73.8 0.7 1.0 1 0 0 1 1 1 1 ATP synthase regulation ATP-synt_ab PF00006.25 KFM83013.1 - 2e-69 233.5 0.0 2.9e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFM83013.1 - 5.3e-12 46.1 0.5 9.4e-12 45.3 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ig_2 PF13895.6 KFM83017.1 - 4e-19 68.7 0.3 8.2e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Peptidase_C14 PF00656.22 KFM83017.1 - 1.3e-18 67.9 1.5 2.5e-18 67.0 1.5 1.5 1 0 0 1 1 1 1 Caspase domain Ig_3 PF13927.6 KFM83017.1 - 2.1e-17 63.5 0.0 2e-11 44.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFM83017.1 - 5.1e-11 42.5 0.0 3.2e-08 33.5 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFM83017.1 - 7.9e-10 38.8 0.0 2.2e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFM83017.1 - 7.7e-08 32.5 0.2 0.0043 17.2 0.0 3.5 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFM83017.1 - 1.6e-07 31.5 0.4 0.00045 20.4 0.0 2.7 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFM83017.1 - 0.0045 17.0 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Raptor_N PF14538.6 KFM83017.1 - 0.017 15.1 0.1 0.064 13.2 0.0 2.0 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Ig_6 PF18452.1 KFM83017.1 - 0.021 14.4 0.1 0.082 12.5 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFM83017.1 - 0.03 14.4 0.0 0.087 12.9 0.0 1.8 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Cys_knot PF00007.22 KFM83019.1 - 6.4e-08 32.8 9.7 6.4e-08 32.8 9.7 3.0 2 1 0 2 2 2 1 Cystine-knot domain Gemin7 PF11095.8 KFM83021.1 - 6.7e-16 57.9 0.0 7.1e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) LSM PF01423.22 KFM83021.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 LSM domain Chitin_bind_4 PF00379.23 KFM83021.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Insect cuticle protein 7tm_1 PF00001.21 KFM83023.1 - 0.0038 16.6 1.6 0.004 16.5 1.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Lig_chan PF00060.26 KFM83024.1 - 1.4e-51 174.3 0.7 2.2e-51 173.6 0.7 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 KFM83024.1 - 1.6e-44 152.4 0.2 2.6e-44 151.8 0.2 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFM83024.1 - 3.5e-40 136.8 0.1 6.7e-40 135.9 0.1 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM83024.1 - 4.6e-17 62.2 0.0 1.4e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 LRR_8 PF13855.6 KFM83025.1 - 4e-23 80.9 13.9 2e-14 53.1 2.9 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM83025.1 - 3e-11 43.4 5.9 1e-06 28.9 0.4 2.6 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM83025.1 - 4.1e-05 23.2 0.9 0.0089 15.5 0.1 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFM83025.1 - 6.2e-05 23.0 5.6 0.93 10.3 0.2 3.8 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 KFM83025.1 - 0.0027 17.6 1.9 3.8 7.8 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_5 PF13306.6 KFM83025.1 - 0.059 13.3 0.0 0.064 13.2 0.0 1.0 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Viral_env_E26 PF11050.8 KFM83025.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Virus envelope protein E26 LRR_8 PF13855.6 KFM83026.1 - 1.1e-06 28.3 0.1 0.0041 16.8 0.1 2.2 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM83026.1 - 2.5e-06 27.7 0.0 0.029 14.8 0.2 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM83026.1 - 0.00012 21.6 0.1 0.00034 20.2 0.1 1.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFM83027.1 - 2e-07 30.6 3.3 3.6e-07 29.9 3.3 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_5 PF13306.6 KFM83027.1 - 0.00085 19.3 0.1 0.0026 17.7 0.1 1.8 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFM83027.1 - 0.0036 17.7 3.8 0.33 11.4 0.7 2.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) 7tm_1 PF00001.21 KFM83029.1 - 0.001 18.5 3.6 0.0016 17.9 3.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SAM_PNT PF02198.16 KFM83031.1 - 5.9e-19 67.8 0.0 1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PHINT_rpt PF14882.6 KFM83031.1 - 0.00077 19.7 0.1 0.0013 18.9 0.1 1.4 1 0 0 1 1 1 1 Phage-integrase repeat unit Polysacc_synt_2 PF02719.15 KFM83032.1 - 0.47 9.5 7.0 0.58 9.2 7.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein V_ATPase_I PF01496.19 KFM83032.1 - 4 5.2 13.7 4.5 5.1 13.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF45 PF01863.17 KFM83032.1 - 4.6 7.2 10.9 6.3 6.8 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 CDC37_N PF03234.14 KFM83032.1 - 7.3 7.5 15.9 11 6.9 15.9 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1002 PF06207.11 KFM83033.1 - 0.088 12.3 0.0 0.088 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DTHCT PF08070.11 KFM83034.1 - 0.022 15.5 13.9 0.022 15.5 13.9 4.5 1 1 2 4 4 4 0 DTHCT (NUC029) region Exo_endo_phos PF03372.23 KFM83035.1 - 0.11 11.9 0.1 0.13 11.8 0.1 1.0 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family CDC45 PF02724.14 KFM83038.1 - 4.3e-134 448.2 9.4 7e-71 239.4 3.3 3.0 1 1 2 3 3 3 3 CDC45-like protein Augurin PF15187.6 KFM83038.1 - 0.12 12.6 0.9 0.25 11.5 0.9 1.5 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 eIF-1a PF01176.19 KFM83039.1 - 1.1e-22 79.5 0.1 1.6e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 eIF-1a PF01176.19 KFM83040.1 - 1.1e-22 79.5 0.1 1.6e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Sod_Cu PF00080.20 KFM83041.1 - 7.3e-48 162.3 0.8 8.8e-48 162.1 0.8 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) YqgF PF14639.6 KFM83043.1 - 1.9e-19 69.9 0.0 2e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 Tex_YqgF PF16921.5 KFM83043.1 - 0.0069 16.8 0.0 0.0071 16.8 0.0 1.0 1 0 0 1 1 1 1 Tex protein YqgF-like domain zf-H2C2_2 PF13465.6 KFM83045.1 - 6.6e-10 39.0 9.7 3.9e-07 30.2 1.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83045.1 - 2.6e-08 33.9 6.8 0.00023 21.5 0.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83045.1 - 2.6e-07 30.9 5.0 0.00084 20.0 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM83045.1 - 3.5e-05 23.4 5.5 8.2e-05 22.3 0.5 2.7 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM83045.1 - 0.00022 21.4 1.0 0.00031 21.0 1.0 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFM83045.1 - 0.0021 18.4 0.3 0.0042 17.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83045.1 - 0.039 14.0 3.5 0.056 13.5 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM83045.1 - 0.04 13.8 0.1 6.4 6.7 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 KFM83045.1 - 0.05 13.2 1.0 3.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2H2_10 PF18414.1 KFM83045.1 - 3.4 7.3 6.1 0.59 9.7 0.4 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger Acyl-CoA_dh_N PF02771.16 KFM83047.1 - 2.7e-27 95.7 0.1 3.7e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM83047.1 - 3.6e-21 75.2 0.0 6.2e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.8 KFM83047.1 - 0.032 13.9 0.0 0.084 12.5 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal CBM_14 PF01607.24 KFM83048.1 - 3.2e-34 116.8 23.7 3.1e-11 43.3 4.0 3.2 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain CLIP_1 PF18322.1 KFM83048.1 - 0.8 9.8 5.5 4.9 7.3 0.1 3.3 3 1 0 3 3 3 0 Serine protease Clip domain PPAF-2 G-patch PF01585.23 KFM83049.1 - 4.4e-14 52.1 0.3 7.9e-14 51.3 0.3 1.4 1 0 0 1 1 1 1 G-patch domain DUF4537 PF15057.6 KFM83049.1 - 0.00049 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) zf-CCCH_4 PF18044.1 KFM83049.1 - 0.0026 17.5 4.8 0.0026 17.5 4.8 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger Agenet PF05641.12 KFM83049.1 - 0.0053 17.2 1.5 0.017 15.6 0.1 2.6 3 0 0 3 3 3 1 Agenet domain TUDOR PF00567.24 KFM83049.1 - 0.027 14.5 0.1 0.084 12.9 0.1 1.9 1 0 0 1 1 1 0 Tudor domain G-patch_2 PF12656.7 KFM83049.1 - 0.052 13.6 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 G-patch domain Tudor_2 PF18104.1 KFM83049.1 - 0.11 12.3 1.5 0.17 11.6 0.6 1.8 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain zf_CCCH_4 PF18345.1 KFM83049.1 - 0.86 9.8 6.7 0.44 10.7 2.3 2.7 2 1 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 KFM83049.1 - 2.3 8.2 5.3 11 6.1 5.3 2.2 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) 2-Hacid_dh PF00389.30 KFM83051.1 - 8.7e-16 57.8 0.0 9.4e-16 57.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PHD PF00628.29 KFM83053.1 - 6.9e-14 51.5 28.4 3.2e-09 36.5 9.2 2.4 1 1 1 2 2 2 2 PHD-finger Linker_histone PF00538.19 KFM83053.1 - 5.2e-09 36.4 0.1 1.9e-05 24.9 0.0 3.5 3 0 0 3 3 3 2 linker histone H1 and H5 family MarR_2 PF12802.7 KFM83053.1 - 0.05 13.5 0.2 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 MarR family HemN_C PF06969.16 KFM83053.1 - 0.055 13.5 0.0 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 HemN C-terminal domain AP3D1 PF06375.11 KFM83053.1 - 0.17 12.1 5.8 0.52 10.5 5.8 1.8 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 zf-LITAF-like PF10601.9 KFM83053.1 - 9.1 6.6 24.2 0.033 14.5 12.8 2.5 1 1 2 3 3 3 0 LITAF-like zinc ribbon domain MOZ_SAS PF01853.18 KFM83054.1 - 6.9e-81 270.2 1.1 1.6e-80 269.0 1.1 1.6 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.7 KFM83054.1 - 0.0025 18.2 0.0 0.0054 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RPA_C PF08784.11 KFM83054.1 - 0.03 15.0 0.3 0.69 10.6 0.0 3.2 2 0 0 2 2 2 0 Replication protein A C terminal RRM_1 PF00076.22 KFM83055.1 - 1.1e-12 47.6 0.0 6.1e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_8 PF13833.6 KFM83056.1 - 4.3e-12 45.7 6.3 3e-07 30.2 0.1 4.0 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM83056.1 - 4e-10 38.8 2.6 0.00049 19.8 0.5 3.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFM83056.1 - 1.3e-09 36.9 12.0 2e-05 23.8 0.8 4.0 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 KFM83056.1 - 8.8e-09 34.5 7.2 2.2e-05 23.7 0.7 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFM83056.1 - 4.8e-07 30.1 6.4 0.0042 17.5 0.4 4.2 4 2 1 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.7 KFM83056.1 - 0.069 13.1 4.6 3.3 7.7 0.1 3.2 3 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand DCX PF03607.17 KFM83057.1 - 3.9e-09 36.5 0.0 6.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Doublecortin HELP PF03451.14 KFM83058.1 - 1.3e-07 31.3 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 KFM83058.1 - 0.11 13.4 0.0 0.24 12.3 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat BssB_TutG PF18512.1 KFM83060.1 - 0.02 14.7 0.2 0.056 13.3 0.2 1.8 1 1 0 1 1 1 0 Benzylsuccinate synthase beta subunit ATP_bind_3 PF01171.20 KFM83060.1 - 0.069 12.9 0.0 0.076 12.8 0.0 1.1 1 0 0 1 1 1 0 PP-loop family DNA_pol_B_palm PF14792.6 KFM83061.1 - 4.5e-32 110.6 0.0 7.8e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KFM83061.1 - 3.3e-22 78.6 2.1 1.8e-18 66.6 0.1 3.3 3 0 0 3 3 3 2 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KFM83061.1 - 1.4e-21 76.0 0.1 5.5e-21 74.1 0.0 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KFM83061.1 - 1.3e-15 57.3 0.0 2.7e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_5 PF14520.6 KFM83061.1 - 1.7e-08 34.9 1.2 2.2e-06 28.2 0.1 2.5 2 1 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 KFM83061.1 - 0.00013 21.6 0.8 0.11 12.4 0.0 3.3 3 0 0 3 3 3 1 Helix-hairpin-helix motif Cdd1 PF11731.8 KFM83061.1 - 0.00055 20.1 0.1 0.008 16.4 0.0 2.3 1 1 1 2 2 2 1 Pathogenicity locus IMS_HHH PF11798.8 KFM83061.1 - 0.0011 19.2 0.1 0.79 10.2 0.0 2.8 2 0 0 2 2 2 1 IMS family HHH motif 5_3_exonuc PF01367.20 KFM83061.1 - 0.0024 18.4 1.9 0.01 16.4 0.3 2.3 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold NTP_transf_2 PF01909.23 KFM83061.1 - 0.006 16.8 0.1 0.013 15.7 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF3701 PF12482.8 KFM83061.1 - 0.0096 16.0 0.0 3.9 7.6 0.0 2.5 2 0 0 2 2 2 1 Phage integrase protein HHH_3 PF12836.7 KFM83061.1 - 0.011 15.9 0.3 0.75 10.1 0.0 2.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif HHH_2 PF12826.7 KFM83061.1 - 0.011 15.8 0.1 5.9 7.1 0.0 2.9 2 1 1 3 3 3 0 Helix-hairpin-helix motif BAF PF02961.14 KFM83061.1 - 0.021 15.2 0.1 6.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Barrier to autointegration factor LPD7 PF18821.1 KFM83061.1 - 0.11 12.6 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 Uso1_p115_C PF04871.13 KFM83062.1 - 1.4e-08 35.1 24.0 1.4e-08 35.1 24.0 2.7 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region SlyX PF04102.12 KFM83062.1 - 0.045 14.4 5.0 0.045 14.4 5.0 4.1 2 2 2 4 4 4 0 SlyX TMF_TATA_bd PF12325.8 KFM83062.1 - 0.077 13.2 39.0 0.36 11.1 8.1 2.8 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding Metalloenzyme PF01676.18 KFM83062.1 - 0.08 12.3 2.8 0.061 12.7 1.2 1.6 1 1 1 2 2 2 0 Metalloenzyme superfamily TMPIT PF07851.13 KFM83062.1 - 0.17 11.1 25.2 0.097 11.9 6.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 KFM83062.1 - 0.21 10.9 19.8 0.076 12.4 16.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Hydrolase_6 PF13344.6 KFM83062.1 - 0.57 10.3 4.2 0.95 9.6 0.4 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Seryl_tRNA_N PF02403.22 KFM83062.1 - 1.8 8.8 35.5 0.2 11.9 16.2 3.2 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 KFM83062.1 - 1.9 7.3 40.6 2 7.3 10.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFM83062.1 - 2.9 8.0 38.2 2.3 8.3 13.8 4.0 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 KFM83062.1 - 4.2 7.7 17.3 2.7 8.3 8.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Rootletin PF15035.6 KFM83062.1 - 4.2 7.3 31.4 11 6.0 26.8 2.7 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion FAM167 PF11652.8 KFM83062.1 - 5.7 7.5 17.1 9.4 6.8 3.3 3.2 1 1 1 2 2 2 0 FAM167 ATG16 PF08614.11 KFM83062.1 - 5.9 7.1 37.0 71 3.5 30.1 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KFM83062.1 - 6.4 6.8 22.6 0.48 10.5 5.7 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DDE_1 PF03184.19 KFM83063.1 - 1.7e-10 40.8 0.0 3.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MFS_1 PF07690.16 KFM83064.1 - 5.4e-14 51.9 10.4 5.9e-14 51.7 10.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM83064.1 - 4e-05 22.7 7.5 6.5e-05 22.0 7.4 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter CbtA PF09490.10 KFM83064.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) DUF3980 PF13140.6 KFM83064.1 - 3.1 8.3 8.6 1.4 9.4 5.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3980) MFS_1 PF07690.16 KFM83065.1 - 1.9e-13 50.1 22.1 8.2e-11 41.4 13.5 2.2 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFM83065.1 - 2.8e-08 32.7 0.4 2.8e-08 32.7 0.4 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein CitMHS PF03600.16 KFM83066.1 - 6.6e-57 193.0 18.8 6.6e-57 193.0 18.8 2.2 2 1 1 3 3 3 1 Citrate transporter ArsB PF02040.15 KFM83066.1 - 8.9e-12 45.1 24.6 3.4e-08 33.2 8.3 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein Na_sulph_symp PF00939.19 KFM83066.1 - 2.9e-11 43.1 34.5 2.6e-06 26.7 13.3 2.8 3 0 0 3 3 3 2 Sodium:sulfate symporter transmembrane region CitMHS_2 PF16980.5 KFM83066.1 - 2.2e-08 33.2 21.3 0.00028 19.7 9.4 2.4 2 0 0 2 2 2 2 Putative citrate transport DPM3 PF08285.11 KFM83066.1 - 0.036 14.2 9.6 0.37 11.0 0.0 4.7 4 0 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF5383 PF17355.2 KFM83066.1 - 5.9 7.3 5.9 37 4.7 0.1 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5383) Ank_2 PF12796.7 KFM83067.1 - 1.7e-52 175.9 8.5 5.7e-15 55.7 0.5 6.1 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM83067.1 - 2.4e-38 130.0 7.7 1.5e-08 35.0 0.2 8.1 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KFM83067.1 - 8.4e-37 124.0 16.2 0.00013 22.3 0.1 10.5 10 1 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.6 KFM83067.1 - 3.1e-35 116.2 15.2 0.00032 20.9 0.0 10.5 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KFM83067.1 - 1.5e-26 92.1 11.0 1.4e-05 25.3 0.1 7.4 3 2 5 8 8 8 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFM83067.1 - 4.1e-07 30.3 1.6 4.1e-07 30.3 1.6 2.4 2 0 0 2 2 2 1 SOCS box Trp_dioxygenase PF03301.13 KFM83069.1 - 1e-142 475.6 4.7 1.2e-142 475.3 4.7 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Ribosomal_L6 PF00347.23 KFM83069.1 - 0.078 13.7 0.2 9.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L6 Peptidase_C1 PF00112.23 KFM83070.1 - 1.4e-53 182.2 1.8 2e-53 181.7 1.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM83070.1 - 2.4e-09 37.5 2.9 4.8e-09 36.5 2.9 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM83070.1 - 1.4e-07 30.7 0.2 0.0009 18.1 0.0 2.4 2 0 0 2 2 2 2 Peptidase C1-like family UPF0004 PF00919.20 KFM83071.1 - 3.4e-21 75.1 0.0 1.1e-20 73.5 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KFM83071.1 - 6.5e-17 62.4 0.1 1.3e-16 61.4 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 KFM83071.1 - 8.6e-08 32.1 0.1 2.3e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 KFM83071.1 - 0.046 13.9 0.0 0.17 12.1 0.0 2.0 1 1 0 1 1 1 0 TRAM domain DDE_Tnp_4 PF13359.6 KFM83072.1 - 8e-11 41.9 0.1 1.1e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM83072.1 - 0.00045 19.9 0.0 0.0007 19.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Antirestrict PF03230.13 KFM83072.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Antirestriction protein Prokineticin PF06607.11 KFM83073.1 - 0.00019 21.7 3.8 0.00023 21.4 3.8 1.1 1 0 0 1 1 1 1 Prokineticin Colipase-like PF15083.6 KFM83073.1 - 0.00058 19.9 6.2 0.0007 19.7 6.2 1.2 1 0 0 1 1 1 1 Colipase-like MIT_LIKE_ACTX PF17556.2 KFM83073.1 - 0.44 11.2 8.5 0.59 10.8 8.5 1.2 1 0 0 1 1 1 0 MIT-like atracotoxin family HIGH_NTase1 PF05636.11 KFM83074.1 - 0.42 9.8 13.5 6.6 5.8 0.0 2.4 1 1 1 2 2 2 0 HIGH Nucleotidyl Transferase MutS_V PF00488.21 KFM83074.1 - 1 9.3 2.7 1.7 8.6 2.7 1.3 1 0 0 1 1 1 0 MutS domain V Tubulin PF00091.25 KFM83077.1 - 5e-69 232.5 0.0 7.9e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM83077.1 - 1.6e-43 147.8 0.1 2.7e-43 147.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFM83077.1 - 3.1e-05 24.3 0.0 7.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KFM83077.1 - 0.0066 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFM83077.1 - 0.0099 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin like Ank_3 PF13606.6 KFM83078.1 - 0.0015 18.8 0.2 1 10.1 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat SSXT PF05030.12 KFM83078.1 - 0.0067 16.0 0.4 0.027 14.1 0.2 2.1 1 1 1 2 2 2 1 SSXT protein (N-terminal region) Ank_2 PF12796.7 KFM83078.1 - 0.067 13.8 0.6 0.32 11.6 0.6 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 KFM83080.1 - 6.8e-10 39.4 0.6 0.0057 17.2 0.9 3.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM83080.1 - 4e-06 27.3 0.7 0.66 10.6 0.3 4.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM83080.1 - 1.9e-05 24.7 0.2 9.6 7.1 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Gliadin PF13016.6 KFM83080.1 - 0.041 14.3 0.4 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 Cys-rich Gliadin N-terminal HIM1 PF08732.10 KFM83080.1 - 0.077 12.5 0.1 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 HIM1 Motile_Sperm PF00635.26 KFM83082.1 - 2.5e-31 107.8 0.2 4.4e-31 107.0 0.2 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain YabA PF06156.13 KFM83082.1 - 0.00011 22.8 1.0 0.00016 22.2 1.0 1.3 1 0 0 1 1 1 1 Initiation control protein YabA bZIP_1 PF00170.21 KFM83082.1 - 0.00096 19.2 4.4 0.0017 18.4 4.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor KASH_CCD PF14662.6 KFM83082.1 - 0.0014 18.4 2.0 0.002 18.0 2.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 KFM83082.1 - 0.0022 18.2 2.3 0.0029 17.7 2.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus NRBF2 PF08961.10 KFM83082.1 - 0.0035 17.0 1.9 0.0053 16.4 1.9 1.2 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator TMF_TATA_bd PF12325.8 KFM83082.1 - 0.0041 17.3 2.6 0.0064 16.7 2.6 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KFM83082.1 - 0.0053 17.3 2.3 0.0078 16.8 2.3 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region ZapB PF06005.12 KFM83082.1 - 0.0067 16.8 8.6 0.012 16.0 8.6 1.3 1 0 0 1 1 1 1 Cell division protein ZapB DUF3450 PF11932.8 KFM83082.1 - 0.012 14.9 1.1 0.018 14.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IFP_35_N PF07334.13 KFM83082.1 - 0.018 15.1 0.4 0.047 13.8 0.4 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DivIC PF04977.15 KFM83082.1 - 0.022 14.5 4.7 0.045 13.5 4.7 1.5 1 0 0 1 1 1 0 Septum formation initiator GAS PF13851.6 KFM83082.1 - 0.027 13.8 6.0 0.038 13.3 6.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 KFM83082.1 - 0.027 14.6 2.5 0.047 13.9 2.5 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Lin-8 PF03353.15 KFM83082.1 - 0.027 14.0 1.3 0.034 13.7 1.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4391 PF14335.6 KFM83082.1 - 0.036 13.8 0.5 0.05 13.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) PRKG1_interact PF15898.5 KFM83082.1 - 0.044 14.7 2.9 0.044 14.7 2.9 1.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain THOC7 PF05615.13 KFM83082.1 - 0.05 13.9 2.3 0.077 13.3 2.3 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 CENP-H PF05837.12 KFM83082.1 - 0.054 13.9 2.6 0.083 13.3 2.6 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Phage_GPO PF05929.11 KFM83082.1 - 0.058 13.0 0.6 0.071 12.7 0.6 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CASP_C PF08172.12 KFM83082.1 - 0.063 12.6 1.6 0.086 12.2 1.6 1.2 1 0 0 1 1 1 0 CASP C terminal Phlebovirus_NSM PF07246.11 KFM83082.1 - 0.065 12.6 0.5 0.092 12.1 0.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4164 PF13747.6 KFM83082.1 - 0.071 13.4 2.3 0.11 12.7 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) bZIP_2 PF07716.15 KFM83082.1 - 0.1 12.7 8.0 0.078 13.1 6.1 1.6 1 1 1 2 2 2 0 Basic region leucine zipper GIT_CC PF16559.5 KFM83082.1 - 0.15 11.9 4.1 0.32 10.9 4.1 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5595 PF18077.1 KFM83082.1 - 0.2 11.7 3.9 0.36 10.9 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) TSC22 PF01166.18 KFM83082.1 - 0.34 11.3 3.6 0.66 10.3 3.6 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Spc24 PF08286.11 KFM83082.1 - 0.44 10.8 2.7 0.75 10.1 2.7 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 HALZ PF02183.18 KFM83082.1 - 1 9.6 5.5 1.2 9.4 2.9 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper MgtE PF01769.16 KFM83083.1 - 3.2e-52 176.1 15.3 1.6e-30 106.0 2.6 3.2 4 0 0 4 4 4 2 Divalent cation transporter TPPK_C PF12555.8 KFM83083.1 - 0.099 12.7 0.0 0.099 12.7 0.0 3.6 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal DUF2160 PF09928.9 KFM83083.1 - 0.11 12.8 0.3 0.11 12.8 0.3 3.0 2 1 0 2 2 2 0 Predicted small integral membrane protein (DUF2160) Herpes_teg_N PF04843.12 KFM83083.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Vps5 PF09325.10 KFM83085.1 - 5e-18 65.5 9.6 1.2e-12 48.0 2.2 2.2 1 1 1 2 2 2 2 Vps5 C terminal like PX PF00787.24 KFM83085.1 - 1.2e-15 57.5 0.1 7.4e-15 54.9 0.0 2.2 2 0 0 2 2 2 1 PX domain Terminase_4 PF05119.12 KFM83085.1 - 0.0054 17.1 0.5 0.016 15.7 0.5 1.8 1 0 0 1 1 1 1 Phage terminase, small subunit Ribosomal_L2_C PF03947.18 KFM83086.1 - 1.9e-05 24.9 0.0 2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFM83087.1 - 3.6e-24 84.5 0.0 6.1e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain CLTH PF10607.9 KFM83088.1 - 5.3e-33 114.0 2.6 9.2e-33 113.2 2.6 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain EAP30 PF04157.16 KFM83088.1 - 0.012 14.9 0.1 0.025 13.9 0.1 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family LisH PF08513.11 KFM83088.1 - 0.092 12.7 0.2 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 LisH zf-RING_UBOX PF13445.6 KFM83088.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.8 3 1 0 3 3 3 0 RING-type zinc-finger Arena_ncap_C PF17290.2 KFM83089.1 - 0.051 12.9 0.3 0.066 12.5 0.3 1.1 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain DHC_N2 PF08393.13 KFM83090.1 - 2.4e-11 43.4 2.7 3.9e-10 39.4 0.2 2.1 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 2 DUF1515 PF07439.11 KFM83090.1 - 0.042 13.9 0.2 0.089 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) MT PF12777.7 KFM83091.1 - 6.6e-35 120.8 0.4 8.6e-35 120.4 0.4 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 KFM83091.1 - 1.2e-29 103.0 0.2 1.2e-29 103.0 0.2 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region Spc7 PF08317.11 KFM83091.1 - 0.012 14.6 5.2 0.019 13.9 5.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KFM83091.1 - 0.013 15.7 0.7 0.026 14.7 0.7 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MAD PF05557.13 KFM83091.1 - 0.027 12.9 2.6 0.036 12.5 2.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein UPF0242 PF06785.11 KFM83091.1 - 0.036 14.2 1.3 0.059 13.5 1.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TBK1_CCD1 PF18394.1 KFM83091.1 - 0.038 13.5 0.5 0.065 12.8 0.6 1.4 1 1 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 Peptidase_U57 PF05582.12 KFM83091.1 - 0.16 11.2 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 YabG peptidase U57 BMFP PF04380.13 KFM83091.1 - 0.29 11.7 6.4 0.12 12.8 1.9 2.4 1 1 1 2 2 2 0 Membrane fusogenic activity Sec34 PF04136.15 KFM83091.1 - 2.4 8.0 5.5 1.4 8.8 2.4 1.9 2 0 0 2 2 2 0 Sec34-like family Dynein_heavy PF03028.15 KFM83094.1 - 3.1e-16 59.5 0.0 4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KFM83095.1 - 2.8e-31 108.6 0.0 3.5e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 KFM83095.1 - 0.025 13.8 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain Dynein_C PF18199.1 KFM83096.1 - 4.7e-93 311.8 0.0 5.3e-93 311.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain TFIID_20kDa PF03847.13 KFM83097.1 - 4.1e-28 97.7 3.2 6.8e-28 97.0 3.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 KFM83097.1 - 0.00056 20.0 0.6 0.0022 18.0 0.1 2.2 1 1 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KFM83097.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM83097.1 - 0.016 15.5 0.0 0.041 14.2 0.0 1.6 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TAF4 PF05236.14 KFM83097.1 - 0.018 14.8 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TM2 PF05154.16 KFM83098.1 - 1.8e-13 50.6 9.3 3e-13 49.9 9.3 1.4 1 0 0 1 1 1 1 TM2 domain BAH PF01426.18 KFM83099.1 - 3.1e-05 23.8 0.0 3.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.6 KFM83101.1 - 6e-12 46.0 0.0 9.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFM83101.1 - 2.7e-10 40.8 0.0 4.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM83101.1 - 7.9e-10 39.4 0.0 4.2e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 KFM83101.1 - 8.4e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KFM83101.1 - 1.7e-05 25.2 0.1 5.4e-05 23.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KFM83101.1 - 0.00062 19.1 0.0 0.69 9.1 0.0 2.1 1 1 1 2 2 2 2 KAP family P-loop domain NACHT PF05729.12 KFM83101.1 - 0.00085 19.3 0.0 0.0021 18.0 0.0 1.6 1 1 0 1 1 1 1 NACHT domain TniB PF05621.11 KFM83101.1 - 0.0025 17.3 0.0 0.0035 16.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial TniB protein AAA_30 PF13604.6 KFM83101.1 - 0.007 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM83101.1 - 0.0074 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFM83101.1 - 0.014 15.3 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KFM83101.1 - 0.027 14.4 0.0 0.068 13.1 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 KFM83101.1 - 0.033 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 KFM83101.1 - 0.093 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 KFM83101.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KFM83101.1 - 0.15 12.0 0.0 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KFM83102.1 - 2.3e-09 37.3 0.3 3.2e-09 36.8 0.3 1.3 1 0 0 1 1 1 1 AAA lid domain DUF2835 PF11197.8 KFM83103.1 - 0.043 13.6 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) Thioredoxin PF00085.20 KFM83104.1 - 1.2e-08 34.9 0.7 8.8e-08 32.1 0.1 2.4 3 0 0 3 3 3 1 Thioredoxin Redoxin PF08534.10 KFM83104.1 - 0.01 15.6 0.1 1.2 8.8 0.0 2.6 2 1 0 2 2 2 0 Redoxin DUF2976 PF11190.8 KFM83105.1 - 0.039 13.8 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Thioredoxin PF00085.20 KFM83105.1 - 0.058 13.4 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin VCBS PF13517.6 KFM83106.1 - 0.00022 21.7 0.0 0.00074 20.1 0.0 2.0 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 KFM83106.1 - 0.00037 19.6 0.1 0.015 14.4 0.0 2.3 1 1 1 2 2 2 2 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 KFM83106.1 - 0.0019 18.2 0.1 9.6 6.3 0.0 3.6 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 KFM83106.1 - 0.0058 16.7 1.0 0.044 13.9 0.2 2.3 2 0 0 2 2 2 1 FG-GAP repeat CPSF_A PF03178.15 KFM83106.1 - 0.007 15.7 0.0 21 4.3 0.0 3.2 2 1 1 3 3 3 2 CPSF A subunit region Ribonuc_red_lgC PF02867.15 KFM83106.1 - 0.058 11.9 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain RCC1_2 PF13540.6 KFM83107.1 - 2.6e-09 36.7 2.4 0.0042 16.9 0.1 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KFM83107.1 - 2.3e-06 28.1 2.7 1.2 9.8 0.0 4.8 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat DUF3449 PF11931.8 KFM83108.1 - 4.8e-79 264.4 1.7 1.1e-78 263.3 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 KFM83108.1 - 6.5e-29 99.4 1.5 1.5e-28 98.2 1.5 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 KFM83108.1 - 2.4e-25 88.8 3.1 6.8e-25 87.4 3.1 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KFM83108.1 - 8.3e-13 48.0 0.7 8.3e-13 48.0 0.7 1.9 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain DUF5404 PF17397.2 KFM83108.1 - 0.019 15.1 0.8 0.043 14.0 0.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5404) zf-met PF12874.7 KFM83108.1 - 0.048 14.1 0.1 0.092 13.2 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ank_2 PF12796.7 KFM83110.1 - 3.2e-14 53.3 4.8 1.9e-13 50.8 4.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM83110.1 - 1.3e-10 41.3 0.8 9.4e-05 22.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Chromo PF00385.24 KFM83110.1 - 1.7e-10 40.7 0.3 4.3e-10 39.3 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ank PF00023.30 KFM83110.1 - 7.8e-10 38.8 1.7 6.5e-05 23.2 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFM83110.1 - 1.4e-08 34.3 0.4 0.00015 21.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFM83110.1 - 2.1e-06 28.2 0.4 1.4e-05 25.6 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MFS_2 PF13347.6 KFM83111.1 - 9.7e-38 129.8 18.2 1.5e-37 129.2 18.2 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KFM83111.1 - 1.7e-17 63.4 15.1 4.2e-13 49.0 6.0 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily ESSS PF10183.9 KFM83111.1 - 0.016 15.4 0.7 0.3 11.3 0.0 2.9 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Insulin PF00049.18 KFM83112.1 - 2.4e-12 47.7 0.1 4.2e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFM83112.1 - 0.0036 17.3 9.6 0.018 15.1 0.6 2.7 3 0 0 3 3 3 2 Nematode insulin-related peptide beta type Insulin PF00049.18 KFM83113.1 - 3.6e-08 34.3 0.4 1e-07 32.9 0.4 1.7 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFM83113.1 - 0.0036 17.3 1.7 1.1 9.3 0.4 2.5 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type DUF2529 PF10740.9 KFM83114.1 - 0.13 11.9 4.1 2 8.1 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2529) Plasmodium_HRP PF05403.11 KFM83114.1 - 0.51 10.1 27.7 2.1 8.1 27.7 1.8 1 1 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) DUF2529 PF10740.9 KFM83115.1 - 0.16 11.6 0.5 2.1 7.9 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2529) SMP PF04927.12 KFM83115.1 - 0.72 10.4 7.4 44 4.7 7.4 2.7 1 1 0 1 1 1 0 Seed maturation protein DUF1943 PF09172.11 KFM83116.1 - 1.4e-25 90.2 137.8 0.0071 15.6 4.5 15.7 1 1 12 13 13 13 11 Domain of unknown function (DUF1943) DUF481 PF04338.12 KFM83116.1 - 2.1e-11 44.2 89.8 0.016 15.3 0.2 13.7 1 1 13 14 14 14 12 Protein of unknown function, DUF481 MspA PF09203.11 KFM83116.1 - 1.2e-08 35.0 109.0 1.8e+04 -91.0 109.0 15.3 1 1 0 1 1 1 0 MspA Bactofilin PF04519.13 KFM83116.1 - 5.5e-08 33.0 52.2 2.2 8.6 0.9 12.8 1 1 12 13 13 13 8 Polymer-forming cytoskeletal XRCC1_N PF01834.16 KFM83117.1 - 1.7e-20 73.5 0.0 1.9e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 XRCC1 N terminal domain Peptidase_C48 PF02902.19 KFM83119.1 - 6.2e-06 26.2 0.4 7.3e-06 26.0 0.4 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 KFM83119.1 - 0.12 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain Acyl-CoA_dh_N PF02771.16 KFM83120.1 - 4.2e-23 82.2 0.2 4.8e-23 82.0 0.2 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain BTB PF00651.31 KFM83121.1 - 4.9e-43 145.9 3.0 6e-27 94.1 1.9 2.7 2 0 0 2 2 2 2 BTB/POZ domain MATH PF00917.26 KFM83121.1 - 2.4e-05 24.5 0.0 0.00047 20.3 0.0 2.7 2 0 0 2 2 2 1 MATH domain Phage_int_SAM_5 PF13102.6 KFM83121.1 - 0.012 16.0 0.2 0.72 10.2 0.0 2.7 2 0 0 2 2 2 0 Phage integrase SAM-like domain PH_4 PF15404.6 KFM83121.1 - 0.073 12.9 0.4 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain DDE_Tnp_1_7 PF13843.6 KFM83122.1 - 0.021 14.1 0.0 0.023 14.0 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 Coiled-coil_56 PF09813.9 KFM83124.1 - 7.3e-07 29.2 0.1 7.6e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Chloroplast_duf PF14476.6 KFM83125.1 - 0.00055 19.0 1.5 0.0006 18.9 1.5 1.0 1 0 0 1 1 1 1 Petal formation-expressed Diphthamide_syn PF01866.17 KFM83125.1 - 0.0023 17.4 0.2 0.0025 17.3 0.2 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DpaA_N PF16924.5 KFM83125.1 - 0.02 15.0 0.1 0.025 14.7 0.1 1.1 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain SH2_2 PF14633.6 KFM83125.1 - 0.046 13.1 0.1 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 SH2 domain SCAN PF02023.17 KFM83126.1 - 2.2e-07 30.6 0.1 3.2e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 SCAN domain LRR_8 PF13855.6 KFM83127.1 - 0.00095 18.9 0.8 0.0024 17.6 0.8 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_8 PF13855.6 KFM83128.1 - 1.2e-23 82.7 16.7 3.4e-12 45.9 4.9 4.0 3 1 1 4 4 4 4 Leucine rich repeat TIR PF01582.20 KFM83128.1 - 2.6e-20 72.9 0.2 4.5e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFM83128.1 - 1.2e-15 58.2 0.1 2.3e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 KFM83128.1 - 2.9e-12 46.6 15.3 0.00014 22.1 0.9 5.7 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFM83128.1 - 5e-08 33.0 0.3 4.6e-06 26.6 0.0 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) DUF1863 PF08937.11 KFM83128.1 - 0.03 14.6 0.1 0.086 13.2 0.1 1.7 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) YokU PF14122.6 KFM83128.1 - 0.075 13.0 0.5 0.62 10.1 0.2 2.2 2 0 0 2 2 2 0 YokU-like protein, putative antitoxin LRR_6 PF13516.6 KFM83128.1 - 0.1 12.7 14.3 0.32 11.1 0.1 6.0 7 0 0 7 7 7 0 Leucine Rich repeat LRR_9 PF14580.6 KFM83128.1 - 0.16 11.5 3.0 9.7 5.7 0.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 KFM83128.1 - 5.9 7.9 13.1 42 5.3 0.1 6.1 4 2 0 4 4 4 0 Leucine Rich Repeat HTH_Tnp_Tc3_2 PF01498.18 KFM83131.1 - 4.4e-16 58.9 3.5 6e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM83131.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM83131.1 - 2.2e-07 30.5 1.2 7.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM83131.1 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM83131.1 - 2.4 8.8 15.6 0.13 12.9 2.0 3.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM83132.1 - 4.4e-16 58.9 3.5 5.9e-16 58.5 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM83132.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM83132.1 - 2.2e-07 30.5 1.2 7.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM83132.1 - 0.0029 17.4 0.6 0.0078 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM83132.1 - 2.6 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain RVT_1 PF00078.27 KFM83133.1 - 8.2e-33 113.8 1.6 9.7e-33 113.5 1.6 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3078 PF11276.8 KFM83133.1 - 0.037 14.5 0.6 6.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3078) HTH_Tnp_Tc3_2 PF01498.18 KFM83134.1 - 1.5e-07 31.6 0.1 1.7e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 Transposase Glyco_transf_6 PF03414.13 KFM83136.1 - 0.078 11.7 0.1 0.078 11.7 0.1 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 6 DDE_Tnp_1_7 PF13843.6 KFM83137.1 - 0.0033 16.8 0.1 0.0047 16.3 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 Pex14_N PF04695.13 KFM83137.1 - 0.11 13.2 0.6 0.16 12.7 0.1 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1258 PF06869.12 KFM83138.1 - 8.1e-07 28.8 0.0 1.4e-06 28.0 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) Transposase_21 PF02992.14 KFM83138.1 - 1.5e-05 24.4 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 RNase_P_p30 PF01876.16 KFM83140.1 - 2.9e-53 180.5 0.6 3.7e-53 180.2 0.6 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Ank_2 PF12796.7 KFM83143.1 - 4.8e-65 216.1 14.1 1.1e-16 61.1 0.1 6.7 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.30 KFM83143.1 - 5e-52 172.2 19.9 4.1e-06 27.0 0.1 11.2 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 KFM83143.1 - 3.2e-49 164.7 14.8 7.6e-09 35.9 0.0 8.6 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM83143.1 - 3.2e-42 142.0 13.5 1.4e-09 38.0 0.0 9.9 4 2 6 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM83143.1 - 9.3e-41 133.2 8.8 0.00011 22.3 0.1 11.3 11 0 0 11 11 11 9 Ankyrin repeat RRM_1 PF00076.22 KFM83144.1 - 2.3e-15 56.1 0.0 5.3e-15 55.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM83144.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFM83144.1 - 0.0008 19.4 0.1 0.0013 18.8 0.1 1.3 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 KFM83144.1 - 0.0056 16.3 0.0 0.0074 15.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KFM83144.1 - 0.05 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) RRM_7 PF16367.5 KFM83144.1 - 0.13 12.4 0.0 2.5 8.3 0.0 2.5 1 1 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 KFM83146.1 - 0.035 13.9 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.6 KFM83147.1 - 3.8e-62 204.1 93.0 2.3e-07 30.9 1.3 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83147.1 - 9.5e-48 158.1 102.0 9.6e-06 25.8 2.0 12.2 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83147.1 - 1.3e-33 112.8 95.0 0.00036 21.1 1.4 12.0 12 0 0 12 12 12 10 C2H2-type zinc finger zf-met PF12874.7 KFM83147.1 - 2.2e-25 88.2 88.0 0.00034 20.9 1.7 11.9 12 0 0 12 12 12 10 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83147.1 - 6.9e-21 73.8 83.7 1.9e-05 24.6 1.0 10.9 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM83147.1 - 3.6e-10 39.8 70.8 0.0081 16.4 0.5 11.4 7 3 4 11 11 11 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM83147.1 - 2.3e-08 33.6 62.6 0.07 12.9 0.5 11.3 11 0 0 11 11 11 5 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM83147.1 - 5.5e-08 32.7 33.2 0.52 10.4 2.3 10.5 3 3 8 11 11 11 3 Sec23/Sec24 zinc finger BolA PF01722.18 KFM83147.1 - 0.0001 22.5 25.6 0.019 15.2 1.7 6.8 2 1 2 5 5 5 1 BolA-like protein zf-DBF PF07535.12 KFM83147.1 - 0.00086 19.4 52.2 4.9 7.3 0.1 10.7 10 1 1 11 11 10 2 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM83147.1 - 0.0024 17.9 47.0 0.91 9.7 8.5 5.0 1 1 2 4 4 4 2 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM83147.1 - 0.0054 16.8 37.9 20 5.4 0.6 10.1 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 KFM83147.1 - 0.01 15.7 49.2 0.72 9.7 0.2 10.5 5 2 7 12 12 11 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFM83147.1 - 0.07 12.9 0.7 0.07 12.9 0.7 10.3 10 0 0 10 10 10 0 zinc-finger C2H2-type FYVE PF01363.21 KFM83147.1 - 0.1 12.7 66.1 0.06 13.5 14.5 6.4 1 1 5 6 6 6 0 FYVE zinc finger PIN7 PF18475.1 KFM83147.1 - 0.13 12.9 0.8 2.4 8.8 0.1 2.9 3 0 0 3 3 3 0 PIN domain TAFII28 PF04719.14 KFM83147.1 - 0.17 12.0 0.7 11 6.2 0.0 3.6 3 2 1 4 4 4 0 hTAFII28-like protein conserved region Mga PF05043.13 KFM83147.1 - 0.22 12.1 4.0 3.1 8.5 0.1 3.8 2 1 0 3 3 3 0 Mga helix-turn-helix domain zf-MYST PF17772.1 KFM83147.1 - 0.34 10.5 53.4 1.6 8.4 0.5 9.8 7 2 3 10 10 10 0 MYST family zinc finger domain MLVIN_C PF18697.1 KFM83149.1 - 0.065 13.3 0.2 0.099 12.8 0.2 1.4 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Fra10Ac1 PF09725.9 KFM83150.1 - 2.2e-49 166.7 6.7 2.2e-49 166.7 6.7 2.6 3 0 0 3 3 3 1 Folate-sensitive fragile site protein Fra10Ac1 DDE_1 PF03184.19 KFM83151.1 - 4.1e-39 134.0 2.2 5.3e-39 133.6 2.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFM83151.1 - 0.00023 20.9 0.1 0.0013 18.5 0.1 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 KFM83152.1 - 1.9e-55 188.6 1.7 2.2e-55 188.4 1.7 1.0 1 0 0 1 1 1 1 Transposase IS4 zf-CCHC PF00098.23 KFM83153.1 - 1.6e-06 27.9 2.5 2.5e-06 27.3 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFM83153.1 - 0.037 13.7 0.6 0.064 13.0 0.6 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFM83153.1 - 0.058 13.1 0.8 0.094 12.5 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle SHNi-TPR PF10516.9 KFM83156.1 - 0.091 12.2 0.1 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 SHNi-TPR Adeno_IVa2 PF02456.15 KFM83158.1 - 0.00018 20.4 0.0 0.00021 20.2 0.0 1.0 1 0 0 1 1 1 1 Adenovirus IVa2 protein T2SSE PF00437.20 KFM83158.1 - 0.00027 20.1 0.0 0.00027 20.1 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein Pox_A32 PF04665.12 KFM83158.1 - 0.00037 20.0 0.0 0.00037 20.0 0.0 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 KFM83158.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.0 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 KFM83158.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KFM83158.1 - 0.014 14.7 0.0 0.015 14.6 0.0 1.0 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 KFM83158.1 - 0.023 14.2 0.0 0.023 14.2 0.0 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KFM83158.1 - 0.031 14.2 0.0 0.031 14.2 0.0 1.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KFM83158.1 - 0.049 13.6 0.0 0.049 13.6 0.0 1.0 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KFM83158.1 - 0.052 13.6 0.0 0.056 13.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM83158.1 - 0.068 13.3 0.1 0.086 13.0 0.1 1.3 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFM83158.1 - 0.081 12.4 0.0 0.081 12.4 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFM83158.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Bacterial TniB protein NB-ARC PF00931.22 KFM83158.1 - 0.15 11.3 0.0 0.15 11.2 0.0 1.0 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KFM83158.1 - 0.15 12.3 0.0 0.15 12.3 0.0 1.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM83158.1 - 0.15 11.9 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 NACHT domain Imm64 PF15600.6 KFM83159.1 - 0.086 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 64 zf-H2C2_2 PF13465.6 KFM83161.1 - 5.7e-30 102.4 34.7 1.8e-07 31.3 0.6 6.1 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83161.1 - 1.9e-22 78.4 46.3 9.9e-06 25.7 4.6 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83161.1 - 2.2e-20 71.6 41.6 0.00071 20.2 0.3 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFM83161.1 - 6.6e-09 35.9 33.7 0.0043 17.4 2.6 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83161.1 - 1.5e-08 34.4 33.7 0.012 15.7 0.6 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger GAGA PF09237.11 KFM83161.1 - 2.9e-08 33.4 19.9 0.042 13.6 0.3 5.0 1 1 4 5 5 5 5 GAGA factor zf-C2H2_jaz PF12171.8 KFM83161.1 - 1.2e-06 28.6 26.5 0.1 12.9 0.7 5.9 5 2 0 5 5 5 2 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM83161.1 - 1.1e-05 25.7 5.7 0.22 11.8 0.1 3.8 1 1 2 3 3 3 3 BolA-like protein ADK_lid PF05191.14 KFM83161.1 - 0.00015 21.7 7.1 0.14 12.2 0.8 3.5 3 1 0 3 3 3 2 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM83161.1 - 0.00032 20.5 15.8 0.81 9.7 0.1 5.5 5 0 0 5 5 5 1 zinc-finger of a C2HC-type zf-RRPl_C4 PF17026.5 KFM83161.1 - 0.0019 18.3 17.7 0.012 15.7 6.9 2.2 1 1 1 2 2 2 2 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_9 PF16293.5 KFM83161.1 - 0.0028 17.4 18.8 3.4 7.6 0.4 5.0 1 1 4 5 5 5 1 C2H2 type zinc-finger (1 copy) zf-HIT PF04438.16 KFM83161.1 - 0.0033 17.3 21.4 4.7 7.2 0.2 5.2 5 0 0 5 5 5 1 HIT zinc finger zf-H2C2_5 PF13909.6 KFM83161.1 - 0.0053 16.5 9.9 0.018 14.8 2.1 6.2 7 0 0 7 7 6 3 C2H2-type zinc-finger domain YyzF PF14116.6 KFM83161.1 - 0.0064 16.5 8.9 19 5.4 0.0 5.1 5 0 0 5 5 5 0 YyzF-like protein C1_1 PF00130.22 KFM83161.1 - 0.0093 15.8 24.3 0.24 11.3 1.5 5.0 1 1 4 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RecR PF02132.15 KFM83161.1 - 0.022 14.3 15.3 19 4.9 0.1 5.1 4 1 0 4 4 4 0 RecR protein DUF2256 PF10013.9 KFM83161.1 - 0.022 14.9 15.4 2.2 8.5 0.1 5.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Baculo_IE-1 PF05290.11 KFM83161.1 - 0.03 14.3 12.9 9.2 6.2 5.8 4.0 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-CHCC PF10276.9 KFM83161.1 - 0.036 14.1 2.6 18 5.5 0.0 4.3 5 0 0 5 5 5 0 Zinc-finger domain Zf_RING PF16744.5 KFM83161.1 - 0.044 13.9 22.0 7.3 6.8 1.2 5.0 1 1 3 4 4 4 0 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KFM83161.1 - 0.053 13.8 32.6 1.2 9.6 3.7 4.9 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFM83161.1 - 0.1 12.3 0.9 0.1 12.3 0.9 4.6 5 0 0 5 5 4 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFM83161.1 - 0.11 12.6 14.1 0.23 11.6 2.4 3.7 2 2 1 3 3 3 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.15 KFM83161.1 - 0.13 12.3 14.5 1.1 9.4 0.1 4.8 4 1 1 5 5 5 0 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM83161.1 - 0.22 11.1 21.7 2.7 7.7 0.3 4.9 1 1 4 5 5 5 0 MYST family zinc finger domain zf-DBF PF07535.12 KFM83161.1 - 0.27 11.4 24.7 3.9 7.7 3.7 5.1 4 1 1 5 5 5 0 DBF zinc finger FYVE PF01363.21 KFM83161.1 - 0.33 11.1 26.1 2.1 8.6 10.9 3.7 1 1 3 4 4 4 0 FYVE zinc finger OSTMP1 PF09777.9 KFM83161.1 - 0.4 10.0 13.8 1.3 8.3 13.8 2.0 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DZR PF12773.7 KFM83161.1 - 0.64 10.1 17.4 1.8e+02 2.2 0.6 3.4 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_8 PF15909.5 KFM83161.1 - 0.67 10.3 23.5 0.39 11.0 1.9 3.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf_UBZ PF18439.1 KFM83161.1 - 0.73 9.5 19.2 8.2 6.1 0.2 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KFM83161.1 - 1.2 9.9 16.7 0.62 10.8 2.8 2.9 1 1 1 2 2 2 0 zinc-ribbon family HNH_5 PF14279.6 KFM83161.1 - 1.2 9.0 22.4 24 4.9 0.8 5.0 2 2 1 3 3 3 0 HNH endonuclease C1_4 PF07975.12 KFM83161.1 - 1.9 8.8 17.4 8.7 6.7 4.0 3.5 1 1 1 3 3 3 0 TFIIH C1-like domain TRAF6_Z2 PF18048.1 KFM83161.1 - 1.9 8.6 25.7 2.1 8.5 0.2 5.1 5 0 0 5 5 4 0 TNF receptor-associated factor 6 zinc finger 2 RAG1_imp_bd PF12560.8 KFM83161.1 - 6.5 6.2 21.9 6.3 6.2 7.7 3.6 1 1 3 4 4 4 0 RAG1 importin binding HNH PF01844.23 KFM83161.1 - 6.7 7.0 25.2 5.1 7.4 0.3 5.1 5 0 0 5 5 5 0 HNH endonuclease zf-H2C2_2 PF13465.6 KFM83162.1 - 2.2e-18 65.7 27.6 2.8e-08 33.8 0.2 4.5 4 2 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83162.1 - 3.6e-15 55.5 24.9 1.1e-05 25.6 0.4 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83162.1 - 7.2e-12 45.1 23.1 0.00014 22.4 0.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFM83162.1 - 4.3e-08 33.3 18.1 0.0075 16.6 0.6 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM83162.1 - 5.8e-06 25.9 7.1 0.059 13.1 0.4 3.7 3 0 0 3 3 3 2 C2H2-type zinc-finger domain GAGA PF09237.11 KFM83162.1 - 0.00031 20.5 3.8 3.1 7.7 0.0 3.0 1 1 2 3 3 3 3 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM83162.1 - 0.0012 18.8 6.6 0.27 11.3 0.1 3.1 2 1 1 3 3 3 1 Sec23/Sec24 zinc finger RecR PF02132.15 KFM83162.1 - 0.0037 16.8 2.1 1.2 8.8 0.0 3.0 3 0 0 3 3 3 1 RecR protein Zf_RING PF16744.5 KFM83162.1 - 0.0044 17.1 14.1 0.43 10.7 1.3 3.0 1 1 2 3 3 3 2 KIAA1045 RING finger A2L_zn_ribbon PF08792.10 KFM83162.1 - 0.0085 15.8 5.0 10 6.0 0.2 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-MYST PF17772.1 KFM83162.1 - 0.0096 15.5 13.9 0.41 10.3 1.3 3.1 1 1 2 3 3 3 2 MYST family zinc finger domain BolA PF01722.18 KFM83162.1 - 0.012 15.9 0.1 1.8 8.9 0.0 2.5 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_jaz PF12171.8 KFM83162.1 - 0.015 15.6 13.1 1.2 9.5 1.2 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-HIT PF04438.16 KFM83162.1 - 0.015 15.2 15.7 0.15 12.0 1.3 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-CCHC_2 PF13696.6 KFM83162.1 - 0.023 14.5 10.9 0.23 11.3 0.7 3.4 3 0 0 3 3 3 0 Zinc knuckle C1_1 PF00130.22 KFM83162.1 - 0.037 13.9 14.1 1.6 8.7 4.4 3.0 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 KFM83162.1 - 0.059 13.1 13.0 0.19 11.5 0.2 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM83162.1 - 0.11 12.6 0.3 0.11 12.6 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-DBF PF07535.12 KFM83162.1 - 0.13 12.4 11.4 5 7.3 0.2 3.5 3 0 0 3 3 3 0 DBF zinc finger ADK_lid PF05191.14 KFM83162.1 - 0.13 12.3 7.3 0.45 10.5 1.9 2.4 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_9 PF16293.5 KFM83162.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) Cas_CXXC_CXXC PF09706.10 KFM83162.1 - 0.21 11.8 6.9 2.2 8.6 0.2 3.1 1 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF5330 PF17264.2 KFM83162.1 - 0.3 11.1 5.0 32 4.6 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5330) DUF2256 PF10013.9 KFM83162.1 - 0.32 11.1 10.4 5.2 7.3 1.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) FlhC PF05280.11 KFM83162.1 - 0.48 10.1 7.1 1.8 8.2 2.4 2.6 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) Baculo_IE-1 PF05290.11 KFM83162.1 - 0.67 9.9 7.9 6.4 6.7 0.3 2.7 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) PHD PF00628.29 KFM83162.1 - 0.91 9.5 12.7 0.81 9.6 4.8 2.2 2 0 0 2 2 2 0 PHD-finger zf-C2H2_2 PF12756.7 KFM83162.1 - 1.4 9.3 14.2 2.2 8.7 0.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.6 KFM83162.1 - 1.5 8.8 8.3 20 5.2 0.1 3.2 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf_UBZ PF18439.1 KFM83162.1 - 1.7 8.3 12.1 2.4 7.9 0.8 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFM83162.1 - 1.8 8.7 11.2 1.2 9.3 3.8 2.6 1 1 2 3 3 3 0 Zinc ribbon domain Prok-RING_1 PF14446.6 KFM83162.1 - 2.1 8.4 14.1 42 4.2 5.6 3.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.21 KFM83162.1 - 2.9 8.1 15.9 6.9 6.9 6.8 2.5 1 1 0 2 2 2 0 FYVE zinc finger Vps39_2 PF10367.9 KFM83162.1 - 3.9 8.0 12.1 7.2 7.1 1.2 3.0 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 TRAF6_Z2 PF18048.1 KFM83162.1 - 5.9 7.1 16.0 1.1 9.4 2.0 2.8 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_7 PF15269.6 KFM83162.1 - 8.4 6.6 15.3 19 5.4 1.9 3.2 1 1 2 3 3 3 0 Zinc-finger zf-H2C2_2 PF13465.6 KFM83163.1 - 1.4e-115 373.0 122.2 1.2e-09 38.1 0.3 19.2 18 1 0 18 18 18 18 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83163.1 - 1.2e-81 264.9 166.6 2.7e-05 24.3 1.4 18.4 18 0 0 18 18 18 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83163.1 - 1.2e-49 162.7 153.7 0.0037 18.0 1.5 18.4 18 0 0 18 18 18 18 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM83163.1 - 9.2e-27 92.5 131.1 0.00081 19.3 0.6 19.0 19 0 0 19 19 19 14 C2H2-type zinc finger zf-met PF12874.7 KFM83163.1 - 1.5e-21 76.1 136.6 0.00037 20.8 1.9 18.4 19 0 0 19 19 18 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83163.1 - 2.1e-17 62.9 103.4 0.033 14.5 1.1 17.8 17 1 1 18 18 18 10 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM83163.1 - 1.7e-05 24.5 36.2 0.01 15.6 0.2 9.9 5 3 7 13 13 12 3 GAGA factor DUF4825 PF16107.5 KFM83163.1 - 0.00012 22.1 0.1 18 5.6 0.0 6.1 5 1 1 6 6 6 0 Domain of unknown function (DUF4825) DUF2256 PF10013.9 KFM83163.1 - 0.00037 20.6 63.9 2.6 8.2 0.1 15.8 17 0 0 17 17 16 1 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.18 KFM83163.1 - 0.00051 20.3 21.7 11 6.3 1.4 8.9 3 1 5 9 9 9 0 BolA-like protein zf-C2H2_2 PF12756.7 KFM83163.1 - 0.0032 17.8 117.8 0.19 12.1 12.9 13.3 1 1 10 11 11 11 4 C2H2 type zinc-finger (2 copies) CTV_P23 PF04808.12 KFM83163.1 - 0.0085 15.7 11.2 0.34 10.4 0.1 5.2 2 2 4 6 6 6 1 Citrus tristeza virus (CTV) P23 protein ADK_lid PF05191.14 KFM83163.1 - 0.012 15.5 0.8 0.012 15.5 0.8 11.0 8 3 3 11 11 10 0 Adenylate kinase, active site lid Baculo_IE-1 PF05290.11 KFM83163.1 - 0.018 15.0 54.7 3.4 7.6 0.3 11.1 1 1 8 10 10 10 0 Baculovirus immediate-early protein (IE-0) DZR PF12773.7 KFM83163.1 - 0.12 12.4 61.5 1e+03 -0.2 10.5 9.0 3 2 0 3 3 2 0 Double zinc ribbon zf-H2C2_5 PF13909.6 KFM83163.1 - 0.23 11.3 0.0 0.23 11.3 0.0 17.7 18 1 0 18 18 17 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 KFM83163.1 - 1.6 9.6 70.9 0.16 12.7 1.2 9.6 1 1 8 11 11 11 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 KFM83163.1 - 2.3 8.9 71.7 0.47 11.1 1.2 12.1 4 3 3 10 10 9 0 Zinc finger C2H2-type, 3 repeats C1_1 PF00130.22 KFM83163.1 - 7.6 6.5 86.7 4.6 7.2 2.0 13.7 5 3 7 13 13 13 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mucin PF01456.17 KFM83164.1 - 0.016 15.2 18.4 0.016 15.2 18.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-H2C2_2 PF13465.6 KFM83166.1 - 1.9e-62 205.1 57.6 6.3e-09 35.9 0.6 10.1 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83166.1 - 3e-43 143.9 70.1 6e-06 26.4 2.6 9.1 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83166.1 - 5.6e-31 104.5 65.7 0.00043 20.9 0.3 9.1 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM83166.1 - 1.5e-23 82.4 63.4 0.00029 21.1 1.0 9.1 8 1 1 9 9 9 8 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM83166.1 - 5e-16 58.1 38.3 0.0031 17.3 0.3 8.4 8 0 0 8 8 8 7 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM83166.1 - 1.3e-14 54.0 39.8 0.029 14.6 0.1 8.6 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83166.1 - 1.7e-11 43.8 54.9 0.027 14.4 0.3 9.4 9 0 0 9 9 9 6 C2H2-type zinc finger ADK_lid PF05191.14 KFM83166.1 - 1.3e-06 28.3 24.2 0.37 10.8 0.9 5.5 4 1 1 5 5 5 5 Adenylate kinase, active site lid BolA PF01722.18 KFM83166.1 - 6.5e-06 26.3 14.0 0.0091 16.2 0.9 5.1 1 1 5 6 6 6 3 BolA-like protein DUF2256 PF10013.9 KFM83166.1 - 2.3e-05 24.4 27.8 2.1 8.5 0.1 8.9 9 0 0 9 9 9 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFM83166.1 - 5.1e-05 23.1 32.8 1.3 9.1 0.1 9.0 9 0 0 9 9 9 3 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM83166.1 - 0.00012 22.0 36.4 3.4 7.8 1.8 8.7 6 3 3 9 9 9 2 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM83166.1 - 0.0014 18.7 34.0 0.16 12.1 3.4 4.2 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-CHCC PF10276.9 KFM83166.1 - 0.0035 17.3 4.3 1.1e+02 3.0 0.0 6.9 8 0 0 8 8 8 0 Zinc-finger domain zf-DBF PF07535.12 KFM83166.1 - 0.0076 16.3 38.0 6.6 6.9 0.1 8.5 8 1 1 9 9 9 1 DBF zinc finger zf-C2H2_9 PF16293.5 KFM83166.1 - 0.011 15.6 39.2 1.5 8.7 0.3 8.6 3 2 6 9 9 9 0 C2H2 type zinc-finger (1 copy) DUF3396 PF11876.8 KFM83166.1 - 0.015 14.8 0.0 30 4.0 0.0 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3396) zinc_ribbon_15 PF17032.5 KFM83166.1 - 0.028 15.2 30.9 2.4 9.0 1.7 4.8 1 1 1 4 4 4 0 zinc-ribbon family zf-HIT PF04438.16 KFM83166.1 - 0.032 14.1 1.3 0.032 14.1 1.3 8.8 9 0 0 9 9 9 0 HIT zinc finger FYVE PF01363.21 KFM83166.1 - 0.081 13.1 51.0 0.053 13.7 7.5 5.8 1 1 4 5 5 5 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KFM83166.1 - 0.15 11.8 52.1 0.38 10.6 0.9 8.2 9 0 0 9 9 9 0 zinc-finger C2H2-type Tox-HNH-HHH PF15637.6 KFM83166.1 - 0.15 12.2 6.8 15 5.8 0.6 3.8 2 1 2 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf_UBZ PF18439.1 KFM83166.1 - 0.23 11.1 32.2 3.5 7.3 0.3 8.2 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger DUF2039 PF10217.9 KFM83166.1 - 2.4 8.6 30.0 5.1 7.5 8.3 4.4 1 1 4 5 5 5 0 Uncharacterized conserved protein (DUF2039) zf-MYST PF17772.1 KFM83166.1 - 2.4 7.8 35.9 4.5 6.9 0.3 7.9 4 3 4 8 8 8 0 MYST family zinc finger domain C5HCH PF17982.1 KFM83166.1 - 5 7.4 41.3 22 5.3 1.2 8.4 5 2 2 8 8 8 0 NSD Cys-His rich domain HNH_5 PF14279.6 KFM83166.1 - 6.5 6.7 42.0 3.2 7.7 2.4 8.0 5 4 1 6 6 6 0 HNH endonuclease zf-H2C2_2 PF13465.6 KFM83167.1 - 3.1e-17 62.1 9.7 2e-06 28.0 0.9 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83167.1 - 2.9e-12 46.3 9.9 3.4e-06 27.2 1.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83167.1 - 2.2e-09 37.4 9.1 0.00027 21.5 1.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFM83167.1 - 3.4e-08 33.6 8.5 0.00022 21.5 0.9 2.4 2 1 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83167.1 - 5.1e-08 32.7 7.4 0.00022 21.1 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM83167.1 - 3.9e-07 29.7 3.2 0.0023 17.7 0.7 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFM83167.1 - 9.7e-05 22.5 4.8 0.011 16.0 0.3 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Dof PF02701.15 KFM83167.1 - 0.00051 20.1 0.4 0.9 9.7 0.0 2.1 1 1 1 2 2 2 2 Dof domain, zinc finger zf-C2H2_2 PF12756.7 KFM83167.1 - 0.00075 19.8 8.9 0.0042 17.4 2.5 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM83167.1 - 0.0011 18.7 3.3 0.044 13.6 0.8 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 KFM83167.1 - 0.0018 18.2 0.4 0.0032 17.4 0.4 1.4 1 1 0 1 1 1 1 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KFM83167.1 - 0.0026 17.5 7.7 0.43 10.4 0.9 3.0 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFM83167.1 - 0.0093 16.2 8.1 0.043 14.1 8.3 1.8 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFM83167.1 - 0.012 15.5 0.7 0.73 9.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM83167.1 - 0.013 16.2 1.3 0.016 16.0 1.3 1.1 1 0 0 1 1 1 0 zinc-ribbon family DUF2256 PF10013.9 KFM83167.1 - 0.015 15.4 0.3 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-BED PF02892.15 KFM83167.1 - 0.037 14.1 8.0 0.21 11.7 1.8 2.2 1 1 1 2 2 2 0 BED zinc finger zf-FPG_IleRS PF06827.14 KFM83167.1 - 0.04 13.8 1.1 6 6.8 0.1 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS HNH_5 PF14279.6 KFM83167.1 - 0.057 13.3 4.1 4.8 7.1 4.3 2.2 1 1 1 2 2 2 0 HNH endonuclease FYVE PF01363.21 KFM83167.1 - 0.099 12.8 5.1 1.3 9.2 5.1 2.0 1 1 0 1 1 1 0 FYVE zinc finger Rtf2 PF04641.12 KFM83167.1 - 0.15 11.4 3.8 1.5 8.1 0.3 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger zf-MYST PF17772.1 KFM83167.1 - 0.15 11.7 2.4 4.9 6.8 0.3 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain zf-HIT PF04438.16 KFM83167.1 - 0.16 11.8 2.1 9 6.3 0.2 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-UBP PF02148.19 KFM83167.1 - 0.26 11.6 6.7 2.1 8.7 6.4 1.9 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf_UBZ PF18439.1 KFM83167.1 - 0.33 10.6 2.8 7.4 6.3 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 KFM83167.1 - 0.41 10.3 6.6 0.45 10.2 0.6 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_12 PF18658.1 KFM83167.1 - 0.49 10.0 5.0 0.61 9.7 1.0 2.2 1 1 1 2 2 2 0 Zinc-finger C2H2-type DUF629 PF04780.12 KFM83167.1 - 1.6 7.1 6.7 3.7 6.0 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) RVT_1 PF00078.27 KFM83168.1 - 7.9e-43 146.5 0.0 1.4e-42 145.7 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) NfrA_C PF13283.6 KFM83169.1 - 0.16 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term DDE_3 PF13358.6 KFM83170.1 - 3.3e-16 59.3 0.1 3.8e-15 55.9 0.0 2.2 1 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM83170.1 - 1.6e-10 41.1 1.0 2.7e-10 40.3 1.0 1.4 1 0 0 1 1 1 1 Transposase zf-C2H2 PF00096.26 KFM83172.1 - 2.7e-25 87.4 109.8 0.0017 18.7 1.5 13.5 13 0 0 13 13 13 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83172.1 - 3.9e-25 86.4 110.7 0.0034 18.1 1.0 13.4 13 0 0 13 13 13 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM83172.1 - 7.6e-25 86.2 105.8 2.7e-07 30.7 1.4 14.0 14 1 0 14 14 14 8 Zinc-finger double domain zf-met PF12874.7 KFM83172.1 - 6.8e-08 32.7 97.2 0.0056 17.0 0.7 13.0 13 0 0 13 13 13 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83172.1 - 9.2e-05 22.3 95.1 0.036 14.1 0.3 12.2 12 0 0 12 12 12 9 C2H2-type zinc finger BolA PF01722.18 KFM83172.1 - 0.002 18.4 5.0 4.5 7.6 0.7 5.5 3 2 0 3 3 3 1 BolA-like protein zf-C2H2_jaz PF12171.8 KFM83172.1 - 0.0021 18.3 87.6 0.054 13.8 0.6 12.3 13 0 0 13 13 13 7 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM83172.1 - 0.03 14.2 0.7 0.03 14.2 0.7 8.9 10 0 0 10 10 10 0 zinc-finger of a C2HC-type SHIPPO-rpt PF07004.12 KFM83173.1 - 2.5e-17 62.9 5.9 1.7e-06 28.6 0.1 3.3 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat TGBp3 PF02495.17 KFM83174.1 - 0.034 13.8 0.1 0.055 13.1 0.1 1.4 1 1 0 1 1 1 0 Triple gene block 3 F-box PF00646.33 KFM83175.1 - 4.1e-10 39.3 1.8 7.9e-10 38.4 1.8 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFM83175.1 - 6.6e-09 35.5 0.2 1.2e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KFM83175.1 - 0.033 13.8 2.1 0.22 11.1 2.1 2.2 1 1 0 1 1 1 0 F-box Tox-URI2 PF15653.6 KFM83178.1 - 0.19 12.0 2.4 18 5.7 0.0 3.0 3 0 0 3 3 3 0 URI fold toxin 2 LisH_TPL PF17814.1 KFM83179.1 - 2.8e-08 33.3 0.8 4.3e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 LisH-like dimerisation domain CLTH PF10607.9 KFM83179.1 - 0.017 15.0 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Silic_transp PF03842.13 KFM83180.1 - 0.053 11.8 1.1 0.054 11.8 1.1 1.0 1 0 0 1 1 1 0 Silicon transporter UDPGP PF01704.18 KFM83184.1 - 1.7e-164 547.4 1.7 2e-164 547.2 1.7 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase UCH PF00443.29 KFM83185.1 - 2.2e-47 161.7 0.2 2.2e-47 161.7 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM83185.1 - 7.2e-11 42.2 13.2 5e-10 39.5 0.4 3.2 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Ran_BP1 PF00638.18 KFM83186.1 - 1.4e-12 48.0 1.5 4.8e-12 46.2 1.5 1.9 1 1 0 1 1 1 1 RanBP1 domain zf-RanBP PF00641.18 KFM83186.1 - 1.2e-05 24.5 26.8 0.00066 18.9 10.9 2.8 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DDE_3 PF13358.6 KFM83186.1 - 0.0012 18.6 0.1 0.0027 17.5 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease PET10 PF17316.2 KFM83186.1 - 0.072 12.6 1.1 0.12 11.9 0.5 1.6 2 0 0 2 2 2 0 Petite colonies protein 10 RVT_1 PF00078.27 KFM83187.1 - 2.1e-53 181.1 0.1 2.8e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Colicin_im PF03857.13 KFM83189.1 - 0.046 13.7 4.9 0.046 13.7 4.9 1.0 1 0 0 1 1 1 0 Colicin immunity protein DNA_pol_B_2 PF03175.13 KFM83192.1 - 1.1e-07 31.1 0.0 1.9e-06 27.1 0.0 1.9 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DUF2975 PF11188.8 KFM83192.1 - 0.031 14.2 4.1 0.049 13.5 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DNA_pol_B_2 PF03175.13 KFM83193.1 - 1e-20 74.1 0.0 1.5e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_F12L PF03337.13 KFM83193.1 - 0.0058 14.9 0.5 0.18 9.9 0.1 2.0 1 1 1 2 2 2 2 Poxvirus F12L protein HTH_Tnp_Tc3_2 PF01498.18 KFM83194.1 - 2.1e-16 59.9 2.2 3.8e-16 59.1 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM83194.1 - 7.6e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Exo_endo_phos_2 PF14529.6 KFM83198.1 - 2.9e-25 88.4 0.0 3.4e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KFM83198.1 - 7.7e-06 25.6 0.1 8.9e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MULE PF10551.9 KFM83199.1 - 1.3e-07 31.9 0.0 3.8e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 KFM83199.1 - 0.036 13.7 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 SWIM zinc finger Plasmod_dom_1 PF09715.10 KFM83199.1 - 0.084 12.9 0.0 0.64 10.1 0.0 2.4 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) PH_14 PF17787.1 KFM83201.1 - 1.2e-21 76.9 0.0 1.3e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 PH domain DUF1627 PF07789.12 KFM83201.1 - 0.17 11.5 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) RVT_1 PF00078.27 KFM83202.1 - 0.1 12.1 0.1 0.11 12.0 0.1 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 KFM83203.1 - 5.6e-52 172.0 41.7 1.4e-08 34.8 0.5 8.1 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83203.1 - 3.9e-37 124.7 50.5 6.8e-06 26.3 2.1 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83203.1 - 5.6e-30 101.4 47.3 0.00022 21.8 0.9 7.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 KFM83203.1 - 1.3e-15 57.2 37.8 0.0016 18.8 0.6 7.3 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83203.1 - 9.4e-13 47.8 45.8 0.0012 18.8 1.1 7.8 7 1 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM83203.1 - 2.3e-10 40.5 32.8 0.067 13.5 0.4 7.3 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM83203.1 - 1e-09 38.0 11.8 0.78 9.6 0.0 6.6 1 1 6 7 7 7 4 GAGA factor zf-H2C2_5 PF13909.6 KFM83203.1 - 7.7e-09 35.2 37.2 0.038 13.8 0.3 7.9 8 0 0 8 8 7 5 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 KFM83203.1 - 2.1e-06 27.5 21.6 0.62 9.9 0.1 6.5 4 2 3 7 7 7 2 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFM83203.1 - 2.2e-06 27.8 5.8 0.23 11.8 0.1 4.8 3 1 0 4 4 4 1 BolA-like protein zf-MYST PF17772.1 KFM83203.1 - 4.1e-06 26.3 27.3 0.78 9.4 0.2 7.0 2 2 5 7 7 7 1 MYST family zinc finger domain zf-C2HC_2 PF13913.6 KFM83203.1 - 6.7e-05 22.7 30.5 0.19 11.7 0.1 7.0 7 0 0 7 7 6 3 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM83203.1 - 8.6e-05 22.5 23.0 0.23 11.6 0.1 6.8 5 2 2 7 7 7 2 Sec23/Sec24 zinc finger ADK_lid PF05191.14 KFM83203.1 - 0.00021 21.2 18.8 0.18 11.8 0.2 5.3 2 1 2 4 4 4 2 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM83203.1 - 0.00066 19.8 0.4 7.4 6.8 0.0 3.2 1 1 2 3 3 3 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_2 PF12756.7 KFM83203.1 - 0.0018 18.5 36.2 1.3 9.4 1.0 6.8 1 1 6 7 7 7 2 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFM83203.1 - 0.0022 17.8 31.6 1.8 8.5 1.7 6.8 1 1 6 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 KFM83203.1 - 0.0046 17.1 22.0 0.065 13.3 7.2 3.4 1 1 2 3 3 3 2 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM83203.1 - 0.0075 16.4 28.3 4.7 7.4 0.1 6.5 7 0 0 7 7 6 1 DBF zinc finger zf-FPG_IleRS PF06827.14 KFM83203.1 - 0.012 15.4 18.0 22 5.0 0.1 6.8 7 0 0 7 7 7 0 Zinc finger found in FPG and IleRS FYVE PF01363.21 KFM83203.1 - 0.021 14.9 29.0 1.6 9.0 6.7 4.3 2 1 1 3 3 3 0 FYVE zinc finger YyzF PF14116.6 KFM83203.1 - 0.024 14.6 15.6 30 4.8 0.0 6.6 7 0 0 7 7 7 0 YyzF-like protein DUF2256 PF10013.9 KFM83203.1 - 0.029 14.5 27.2 7.8 6.7 1.2 6.9 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFM83203.1 - 0.085 13.6 22.0 0.69 10.7 0.5 3.9 1 1 2 3 3 3 0 zinc-ribbon family TRAF6_Z2 PF18048.1 KFM83203.1 - 0.089 12.9 28.4 3.4 7.8 0.4 6.9 7 0 0 7 7 7 0 TNF receptor-associated factor 6 zinc finger 2 zf-HIT PF04438.16 KFM83203.1 - 0.12 12.3 34.6 6.2 6.8 0.2 7.0 7 0 0 7 7 7 0 HIT zinc finger Prok-RING_1 PF14446.6 KFM83203.1 - 0.18 11.8 23.9 5.2 7.1 0.1 6.7 7 0 0 7 7 7 0 Prokaryotic RING finger family 1 DUF2039 PF10217.9 KFM83203.1 - 0.26 11.7 21.9 6.4 7.2 7.6 3.9 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2039) zf-CHCC PF10276.9 KFM83203.1 - 0.35 11.0 8.3 11 6.2 0.0 5.1 6 0 0 6 6 5 0 Zinc-finger domain PqqA PF08042.11 KFM83203.1 - 0.65 10.1 3.4 2.4e+02 2.0 0.0 4.8 5 0 0 5 5 5 0 PqqA family zf_UBZ PF18439.1 KFM83203.1 - 0.87 9.2 32.8 2.2 7.9 0.3 7.1 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger Zf_RING PF16744.5 KFM83203.1 - 0.95 9.6 29.6 6.9 6.9 0.3 6.6 1 1 3 5 5 5 0 KIAA1045 RING finger RecR PF02132.15 KFM83203.1 - 1.3 8.6 19.5 15 5.3 0.1 6.2 6 1 0 6 6 6 0 RecR protein HNH_5 PF14279.6 KFM83203.1 - 2 8.4 30.4 17 5.4 0.1 6.6 5 2 1 6 6 6 0 HNH endonuclease Zn-ribbon_8 PF09723.10 KFM83203.1 - 2.8 8.2 25.9 2.3 8.4 0.9 4.8 2 1 4 6 6 6 0 Zinc ribbon domain HNH PF01844.23 KFM83203.1 - 3.3 7.9 31.4 8 6.7 0.3 7.0 7 0 0 7 7 7 0 HNH endonuclease zf-Paramyx-P PF13008.7 KFM83203.1 - 4.1 6.9 22.1 38 3.8 0.0 6.6 7 0 0 7 7 7 0 Zinc-binding domain of Paramyxoviridae V protein zf-H2C2_2 PF13465.6 KFM83204.1 - 3.5e-15 55.7 17.9 5.8e-07 29.7 0.3 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83204.1 - 1.3e-10 41.2 20.5 0.00033 20.9 1.0 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83204.1 - 2.7e-07 30.9 16.9 0.003 18.3 0.6 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM83204.1 - 7.3e-06 25.8 4.8 0.0012 18.8 0.7 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KFM83204.1 - 0.00012 22.3 8.2 0.057 13.8 1.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_1 PF00130.22 KFM83204.1 - 0.03 14.2 5.5 0.5 10.3 0.4 2.6 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MYST PF17772.1 KFM83204.1 - 0.046 13.3 5.0 0.18 11.4 1.2 2.4 1 1 1 2 2 2 0 MYST family zinc finger domain zf-H2C2_5 PF13909.6 KFM83204.1 - 0.1 12.3 16.9 0.34 10.7 2.5 3.5 3 1 0 3 3 3 0 C2H2-type zinc-finger domain BolA PF01722.18 KFM83204.1 - 0.11 12.7 0.5 0.29 11.4 0.0 2.0 2 1 0 2 2 2 0 BolA-like protein zf-C2H2_11 PF16622.5 KFM83204.1 - 0.3 10.9 13.9 0.84 9.5 1.6 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type FYVE PF01363.21 KFM83204.1 - 0.74 10.0 4.7 6.7 6.9 3.4 2.2 1 1 1 2 2 2 0 FYVE zinc finger Zn-C2H2_12 PF18112.1 KFM83204.1 - 9.2 6.8 8.5 87 3.7 0.1 3.8 4 1 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain TH1 PF04858.13 KFM83205.1 - 6.8e-283 939.6 0.6 7.7e-283 939.4 0.6 1.0 1 0 0 1 1 1 1 TH1 protein LSM14 PF12701.7 KFM83205.1 - 0.037 14.1 0.2 5.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Scd6-like Sm domain zf-met PF12874.7 KFM83206.1 - 1e-21 76.5 34.0 0.00013 22.2 0.9 8.5 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83206.1 - 3.2e-16 59.1 28.7 0.00016 21.8 0.1 8.2 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM83206.1 - 3.6e-12 46.5 33.0 0.055 13.8 0.4 7.0 2 2 6 8 8 8 5 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM83206.1 - 2.1e-07 31.2 25.3 0.063 14.2 0.1 7.9 8 0 0 8 8 8 4 C2H2-type zinc finger zf-UBP_var PF17807.1 KFM83206.1 - 0.0017 18.1 0.1 0.073 12.8 0.0 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger zf-C2H2 PF00096.26 KFM83206.1 - 0.005 17.2 32.0 0.14 12.7 0.2 7.8 8 0 0 8 8 8 3 Zinc finger, C2H2 type VATC PF18716.1 KFM83206.1 - 0.21 11.4 20.1 1.4 8.9 0.0 6.1 6 0 0 6 6 6 0 Vms1-associating treble clef domain zf-DBF PF07535.12 KFM83206.1 - 0.46 10.6 32.3 1.2 9.3 0.1 7.4 7 0 0 7 7 7 0 DBF zinc finger zf-BED PF02892.15 KFM83206.1 - 0.52 10.4 20.9 2.3 8.3 0.0 6.3 7 0 0 7 7 7 0 BED zinc finger zf-FCS PF06467.14 KFM83206.1 - 1.1 9.3 13.1 0.22 11.5 0.3 4.6 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif Fer4_16 PF13484.6 KFM83206.1 - 7.4 7.6 22.9 4.4 8.3 2.2 5.4 5 2 1 6 6 6 0 4Fe-4S double cluster binding domain PAP_RNA-bind PF04926.15 KFM83207.1 - 7e-09 35.5 0.0 7.1e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain HTH_Tnp_Tc3_2 PF01498.18 KFM83208.1 - 1.9e-16 60.0 2.2 4.2e-16 58.9 2.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM83208.1 - 8.8e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM83209.1 - 2.3e-16 59.8 2.2 4.4e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM83209.1 - 9.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM83210.1 - 3e-68 223.4 73.9 2.1e-08 34.2 1.1 12.0 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83210.1 - 1.1e-37 126.4 97.8 1.9e-05 24.9 2.8 10.4 11 0 0 11 11 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83210.1 - 2.7e-33 111.7 87.8 0.0014 19.2 3.5 10.4 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM83210.1 - 4.3e-14 52.1 74.5 0.0024 17.8 0.9 10.6 10 0 0 10 10 10 8 C2H2-type zinc finger zf-met PF12874.7 KFM83210.1 - 5.4e-11 42.5 84.3 0.031 14.7 3.4 10.5 10 0 0 10 10 10 7 Zinc-finger of C2H2 type BolA PF01722.18 KFM83210.1 - 3.8e-06 27.1 9.7 0.69 10.2 0.1 5.2 2 1 3 5 5 5 2 BolA-like protein zf-C2H2_jaz PF12171.8 KFM83210.1 - 5.7e-06 26.5 65.4 0.019 15.3 1.0 10.6 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM83210.1 - 6.2e-05 23.0 46.1 0.074 13.1 1.8 9.0 6 3 2 8 8 8 4 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.6 KFM83210.1 - 0.002 17.8 72.0 0.022 14.5 1.8 10.8 11 1 0 11 11 11 4 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM83210.1 - 0.015 15.1 1.4 0.015 15.1 1.4 9.6 10 0 0 10 10 10 0 zinc-finger C2H2-type zf-CCHC_2 PF13696.6 KFM83210.1 - 1.4 8.8 33.3 8.6 6.3 0.2 7.8 7 0 0 7 7 7 0 Zinc knuckle FYVE PF01363.21 KFM83210.1 - 1.4 9.1 65.1 1.1 9.4 11.7 6.4 2 2 3 5 5 4 0 FYVE zinc finger C1_4 PF07975.12 KFM83210.1 - 1.7 8.9 62.1 1.1 9.6 3.7 7.3 3 2 4 8 8 7 0 TFIIH C1-like domain Zf_RING PF16744.5 KFM83210.1 - 5.2 7.3 52.0 0.056 13.6 2.2 7.6 2 1 6 8 8 8 0 KIAA1045 RING finger zf-C2H2_4 PF13894.6 KFM83211.1 - 1e-26 91.3 113.6 0.0016 19.1 0.1 15.6 15 0 0 15 15 15 12 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM83211.1 - 7.4e-21 73.6 97.7 3.6e-08 33.5 0.8 14.8 15 1 0 15 15 15 9 Zinc-finger double domain zf-met PF12874.7 KFM83211.1 - 8.9e-21 73.6 99.1 0.0039 17.5 0.7 15.7 15 1 0 15 15 15 11 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFM83211.1 - 2.5e-20 71.7 119.6 0.00037 20.8 0.2 15.4 15 0 0 15 15 15 12 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFM83211.1 - 1.2e-12 47.8 107.3 0.00076 19.7 2.8 15.4 15 0 0 15 15 15 9 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM83211.1 - 9.9e-06 25.2 25.8 0.11 12.2 0.5 7.6 8 0 0 8 8 8 4 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFM83211.1 - 0.0018 18.2 5.8 0.021 14.8 0.2 14.6 15 0 0 15 15 15 8 C2H2-type zinc finger DDE_3 PF13358.6 KFM83213.1 - 1.3e-10 41.2 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RIG-I_C-RD PF11648.8 KFM83214.1 - 0.071 13.3 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I MEDS PF14417.6 KFM83214.1 - 0.074 12.9 0.0 0.093 12.6 0.0 1.1 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain RVT_1 PF00078.27 KFM83215.1 - 9.4e-07 28.6 0.0 2.1e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glycos_transf_2 PF00535.26 KFM83217.1 - 3e-24 85.7 0.0 3.8e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KFM83217.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF4338 PF14236.6 KFM83218.1 - 0.02 14.2 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) HTH_Tnp_Tc3_2 PF01498.18 KFM83219.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM83219.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RNA_pol_I_A49 PF06870.12 KFM83220.1 - 4e-59 200.4 2.8 4.8e-59 200.2 2.8 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Phage_T4_Ndd PF06591.11 KFM83220.1 - 0.05 13.4 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) PulA_N1 PF17999.1 KFM83220.1 - 0.28 11.9 3.8 1.2 9.9 0.0 2.9 3 0 0 3 3 3 0 Pullulanase N1-terminal domain I-set PF07679.16 KFM83221.1 - 3e-23 81.7 0.2 2e-14 53.4 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM83221.1 - 4.7e-13 49.5 0.0 1.1e-07 32.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM83221.1 - 2.4e-07 30.8 0.5 0.017 15.3 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM83221.1 - 4.1e-06 27.0 0.1 0.064 13.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM83221.1 - 1.8e-05 24.9 0.1 0.089 13.0 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFM83221.1 - 0.0004 19.9 0.0 0.0049 16.4 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFM83221.1 - 0.0021 18.1 0.2 0.63 10.1 0.1 2.2 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFM83221.1 - 0.0024 18.1 0.2 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Pex19 PF04614.12 KFM83222.1 - 3.8e-44 151.3 6.9 5.8e-44 150.7 6.9 1.4 1 1 0 1 1 1 1 Pex19 protein family FliD_C PF07195.12 KFM83222.1 - 0.0015 18.0 0.1 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus DUF713 PF05218.14 KFM83222.1 - 0.097 12.4 2.0 0.081 12.7 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF713) 60KD_IMP PF02096.20 KFM83222.1 - 0.37 10.7 3.5 0.62 9.9 3.5 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein PMC2NT PF08066.12 KFM83222.1 - 1.1 10.0 3.5 9.7 7.0 0.3 3.2 2 2 0 3 3 3 0 PMC2NT (NUC016) domain DUF3035 PF11233.8 KFM83223.1 - 0.044 14.1 1.6 4.8 7.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3035) zf-H2C2_2 PF13465.6 KFM83224.1 - 6.2e-174 557.5 194.3 6e-09 35.9 1.8 27.1 27 0 0 27 27 27 26 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83224.1 - 3.1e-122 392.7 233.5 2.1e-05 24.7 0.4 26.1 26 0 0 26 26 26 26 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83224.1 - 1.9e-88 283.3 216.3 0.00075 20.1 0.9 26.1 26 0 0 26 26 26 26 C2H2-type zinc finger zf-met PF12874.7 KFM83224.1 - 1.7e-64 212.5 195.7 9.4e-05 22.7 1.0 26.3 26 0 0 26 26 26 22 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83224.1 - 1.7e-48 162.0 136.4 0.036 14.4 0.2 26.4 26 0 0 26 26 26 20 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM83224.1 - 4.7e-31 106.2 164.3 0.07 12.9 0.8 26.3 26 0 0 26 26 26 18 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFM83224.1 - 6e-19 67.5 161.3 0.061 13.1 0.1 25.5 26 0 0 26 26 26 15 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.15 KFM83224.1 - 2.3e-18 65.9 83.0 0.26 11.4 0.0 23.0 18 5 7 25 25 25 4 Sec23/Sec24 zinc finger zf-RRPl_C4 PF17026.5 KFM83224.1 - 5.7e-13 48.9 111.0 0.12 12.4 5.5 10.5 1 1 10 11 11 11 11 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_6 PF13912.6 KFM83224.1 - 1e-08 35.0 171.2 0.053 13.5 0.2 26.2 26 0 0 26 26 26 7 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFM83224.1 - 1.8e-07 31.8 115.0 0.31 11.8 2.0 13.5 1 1 19 20 20 20 10 zinc-ribbon family DUF2256 PF10013.9 KFM83224.1 - 9.2e-07 28.9 102.7 6.6 6.9 0.1 24.0 25 0 0 25 25 25 1 Uncharacterized protein conserved in bacteria (DUF2256) DZR PF12773.7 KFM83224.1 - 2.3e-06 27.5 97.3 0.65 10.1 0.6 14.0 3 2 2 5 5 2 1 Double zinc ribbon BolA PF01722.18 KFM83224.1 - 1e-05 25.7 50.9 12 6.3 1.3 15.0 3 2 8 11 11 11 0 BolA-like protein Mga PF05043.13 KFM83224.1 - 2.9e-05 24.6 13.1 33 5.2 0.0 8.0 6 3 1 8 8 8 0 Mga helix-turn-helix domain Tox-HNH-HHH PF15637.6 KFM83224.1 - 0.00011 22.3 11.5 16 5.7 0.1 8.1 2 2 8 11 11 11 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-DBF PF07535.12 KFM83224.1 - 0.0019 18.2 116.1 14 5.9 0.3 24.5 26 0 0 26 26 25 0 DBF zinc finger Ring_hydroxyl_B PF00866.18 KFM83224.1 - 0.0023 18.0 0.0 1.6e+02 2.3 0.0 6.2 4 4 4 8 8 7 0 Ring hydroxylating beta subunit GAGA PF09237.11 KFM83224.1 - 0.0045 16.8 59.8 2.4 8.0 0.0 15.3 4 4 16 21 21 21 2 GAGA factor HEPPP_synt_1 PF07307.11 KFM83224.1 - 0.0064 16.1 17.2 0.26 10.9 0.9 5.6 2 2 2 6 6 6 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 NAD_kinase PF01513.21 KFM83224.1 - 0.069 12.3 13.9 14 4.8 0.1 6.4 3 1 1 4 4 4 0 ATP-NAD kinase DUF4806 PF16064.5 KFM83224.1 - 0.12 12.7 31.6 4.2 7.7 0.2 9.7 4 3 5 10 10 10 0 Domain of unknown function (DUF4806) zf-C2HC_2 PF13913.6 KFM83224.1 - 0.63 10.0 87.8 0.78 9.7 0.1 20.0 23 0 0 23 23 22 0 zinc-finger of a C2HC-type zf-Dof PF02701.15 KFM83224.1 - 1.1 9.5 87.4 0.091 12.9 1.6 18.2 6 4 16 22 22 22 0 Dof domain, zinc finger C1_1 PF00130.22 KFM83224.1 - 4.8 7.1 141.5 2.9 7.8 2.7 19.2 2 2 19 21 21 21 0 Phorbol esters/diacylglycerol binding domain (C1 domain) M-factor PF03855.13 KFM83224.1 - 5.7 7.2 20.8 1.4e+02 2.7 0.1 9.8 11 0 0 11 11 11 0 M-factor zf-H2C2_2 PF13465.6 KFM83226.1 - 7.2e-78 253.8 126.8 6.7e-07 29.5 1.0 15.2 15 0 0 15 15 15 15 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83226.1 - 6e-39 130.4 147.1 0.00012 22.4 0.5 14.1 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83226.1 - 8e-36 119.6 143.3 0.0027 18.4 0.7 14.2 14 0 0 14 14 14 14 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM83226.1 - 1.2e-30 104.8 81.8 0.0058 16.4 0.4 14.4 14 0 0 14 14 14 11 C2H2-type zinc-finger domain BolA PF01722.18 KFM83226.1 - 1.5e-16 60.4 21.3 0.16 12.3 0.1 10.0 1 1 6 9 9 9 5 BolA-like protein zf-met PF12874.7 KFM83226.1 - 7.1e-11 42.1 144.0 0.18 12.3 0.6 14.6 14 0 0 14 14 14 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83226.1 - 3.2e-07 30.2 94.4 0.14 12.2 0.3 15.5 14 0 0 14 14 14 5 C2H2-type zinc finger PUF PF00806.19 KFM83226.1 - 6.2e-07 28.8 1.2 65 3.5 0.0 9.0 10 0 0 10 10 10 0 Pumilio-family RNA binding repeat DUF4990 PF16380.5 KFM83226.1 - 1.2e-05 25.4 8.8 76 3.4 0.0 9.2 10 0 0 10 10 10 0 Domain of unknown function zf-RRPl_C4 PF17026.5 KFM83226.1 - 0.00021 21.4 73.8 0.99 9.5 4.0 7.1 1 1 6 7 7 7 3 Putative ribonucleoprotein zinc-finger pf C4 type CBP_BcsQ PF06564.12 KFM83226.1 - 0.00055 19.5 18.9 6.1 6.2 0.2 6.4 1 1 6 7 7 7 2 Cellulose biosynthesis protein BcsQ SPARC_Ca_bdg PF10591.9 KFM83226.1 - 0.0028 18.0 7.2 1.1 9.6 0.2 3.9 4 0 0 4 4 3 2 Secreted protein acidic and rich in cysteine Ca binding region PqqA PF08042.11 KFM83226.1 - 0.0064 16.5 11.4 5.3e+02 0.9 0.0 10.0 12 0 0 12 12 12 0 PqqA family ATP-grasp_4 PF13535.6 KFM83226.1 - 0.036 13.7 0.0 34 4.0 0.0 3.8 3 1 0 3 3 3 0 ATP-grasp domain GAGA PF09237.11 KFM83226.1 - 0.16 11.8 54.7 0.41 10.5 0.3 11.5 3 3 10 13 13 13 0 GAGA factor zf-CHCC PF10276.9 KFM83226.1 - 0.33 11.0 23.8 49 4.1 0.0 10.7 14 0 0 14 14 14 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KFM83226.1 - 0.52 10.3 54.7 2.9 7.9 0.1 13.3 14 0 0 14 14 14 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KFM83226.1 - 2.6 8.4 118.2 0.28 11.5 3.6 12.5 1 1 13 14 14 14 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KFM83227.1 - 4.2e-37 124.9 39.3 2.9e-07 30.6 0.1 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83227.1 - 7.3e-30 101.7 48.7 2.8e-07 30.6 1.1 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83227.1 - 1.8e-22 78.0 44.8 0.0013 19.3 0.6 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFM83227.1 - 3.2e-11 43.2 40.4 0.054 13.9 1.0 6.2 6 0 0 6 6 6 5 Zinc-finger of C2H2 type BolA PF01722.18 KFM83227.1 - 9.9e-09 35.4 0.0 0.79 10.0 0.0 5.3 1 1 3 4 4 4 2 BolA-like protein zf-C2H2_jaz PF12171.8 KFM83227.1 - 9.3e-08 32.2 31.9 0.022 15.1 0.9 6.3 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83227.1 - 9.4e-07 28.7 31.2 0.41 10.7 0.5 6.3 6 0 0 6 6 6 4 C2H2-type zinc finger zf-Di19 PF05605.12 KFM83227.1 - 1.7e-05 25.0 25.4 0.0089 16.3 3.8 4.0 2 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Zf_RING PF16744.5 KFM83227.1 - 6.6e-05 22.9 22.9 1.5 9.0 0.2 5.8 1 1 4 6 6 6 3 KIAA1045 RING finger zf-BED PF02892.15 KFM83227.1 - 0.00036 20.5 38.5 0.14 12.2 1.1 6.1 2 1 4 6 6 6 4 BED zinc finger zf-H2C2_5 PF13909.6 KFM83227.1 - 0.00047 19.9 23.3 0.65 9.8 1.7 5.6 5 0 0 5 5 5 3 C2H2-type zinc-finger domain DUF2256 PF10013.9 KFM83227.1 - 0.025 14.7 17.6 4.1 7.6 0.1 5.8 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 KFM83227.1 - 0.029 14.2 8.7 4.1 7.3 0.1 4.7 2 2 3 5 5 5 0 GAGA factor zf-C2H2_3rep PF18868.1 KFM83227.1 - 0.06 14.0 22.5 3.7 8.2 0.8 5.5 1 1 5 6 6 6 0 Zinc finger C2H2-type, 3 repeats zf-CCHC_2 PF13696.6 KFM83227.1 - 0.079 12.8 21.3 1.3 8.9 0.8 5.5 5 0 0 5 5 5 0 Zinc knuckle Zn-ribbon_8 PF09723.10 KFM83227.1 - 0.18 12.0 24.3 8.5 6.6 1.4 5.4 4 1 2 6 6 6 0 Zinc ribbon domain zf_UBZ PF18439.1 KFM83227.1 - 0.27 10.9 18.6 3.8 7.2 0.1 5.8 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KFM83227.1 - 0.4 10.6 16.9 25 4.8 0.1 5.7 4 1 2 6 6 6 0 C2H2 type zinc-finger (1 copy) C1_2 PF03107.16 KFM83227.1 - 0.48 10.8 32.7 3.1 8.2 3.0 5.9 1 1 3 4 4 4 0 C1 domain zinc_ribbon_15 PF17032.5 KFM83227.1 - 0.54 11.0 19.7 7.4 7.4 3.4 3.4 1 1 2 3 3 3 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 KFM83227.1 - 0.6 10.2 30.5 0.72 10.0 1.1 5.5 5 1 1 6 6 6 0 Sec23/Sec24 zinc finger FYVE PF01363.21 KFM83227.1 - 0.67 10.1 32.7 19 5.5 1.4 4.8 1 1 2 3 3 2 0 FYVE zinc finger Elf1 PF05129.13 KFM83227.1 - 1.5 8.9 22.7 0.11 12.5 1.6 3.7 2 2 2 4 4 4 0 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 KFM83227.1 - 3.6 7.4 40.4 4.5 7.1 2.8 6.0 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-MYST PF17772.1 KFM83227.1 - 3.7 7.2 22.8 2.2 7.9 0.3 5.2 3 2 3 6 6 6 0 MYST family zinc finger domain HTH_Tnp_Tc3_2 PF01498.18 KFM83228.1 - 7.5e-16 58.1 2.2 7.5e-16 58.1 2.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM83228.1 - 1.8e-13 50.5 0.0 3.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease LSM PF01423.22 KFM83228.1 - 1.3e-07 31.2 0.1 1.6e-06 27.7 0.1 2.2 1 1 0 1 1 1 1 LSM domain GAIN_A PF18619.1 KFM83229.1 - 0.007 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Rnk_N PF14760.6 KFM83229.1 - 0.013 16.0 3.2 0.12 12.9 1.2 2.2 2 0 0 2 2 2 0 Rnk N-terminus Ubiq_cyt_C_chap PF03981.12 KFM83229.1 - 0.013 15.6 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone HTH_24 PF13412.6 KFM83229.1 - 0.016 14.8 0.9 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding CoA_trans PF01144.23 KFM83230.1 - 2.3e-17 63.1 0.1 2.9e-17 62.8 0.1 1.1 1 0 0 1 1 1 1 Coenzyme A transferase DUF2116 PF09889.9 KFM83232.1 - 7.4 6.6 11.2 0.084 12.9 2.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PAH PF02671.21 KFM83234.1 - 0.026 14.7 0.3 0.059 13.5 0.3 1.7 1 0 0 1 1 1 0 Paired amphipathic helix repeat DUF4806 PF16064.5 KFM83236.1 - 1.1e-08 35.2 0.0 1.4e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4806) Lipase PF00151.19 KFM83237.1 - 0.0035 16.7 0.0 0.0035 16.7 0.0 1.0 1 0 0 1 1 1 1 Lipase TF_AP-2 PF03299.14 KFM83237.1 - 0.0068 16.4 0.0 0.0068 16.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor AP-2 Imm31 PF15591.6 KFM83238.1 - 0.013 15.3 8.0 42 4.1 0.1 6.2 7 0 0 7 7 7 0 Immunity protein 31 Toxin_7 PF05980.12 KFM83240.1 - 0.1 12.9 3.4 0.1 12.9 3.4 1.8 2 1 0 2 2 2 0 Toxin 7 Conotoxin PF02950.17 KFM83240.1 - 1.3 10.1 7.0 5.8 8.0 7.0 1.9 1 1 0 1 1 1 0 Conotoxin DDE_Tnp_1_7 PF13843.6 KFM83242.1 - 5.6e-75 252.8 0.7 7e-75 252.5 0.7 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM83242.1 - 3.7e-05 23.5 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 KFM83242.1 - 0.024 14.6 0.3 0.058 13.4 0.3 1.6 1 0 0 1 1 1 0 Transposase DDE domain CAF1A PF12253.8 KFM83242.1 - 1.1 9.5 6.6 2.5 8.3 6.6 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Tugs PF17840.1 KFM83243.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain HTH_Tnp_Tc3_2 PF01498.18 KFM83246.1 - 8.9e-15 54.7 1.3 1.6e-14 53.9 1.3 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM83246.1 - 1.6e-05 25.5 7.3 3.4e-05 24.4 2.6 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KFM83246.1 - 0.00028 20.9 0.5 0.013 15.6 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 KFM83246.1 - 0.00084 19.4 2.1 0.051 13.7 0.1 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM83246.1 - 0.0013 18.5 2.0 0.11 12.4 0.1 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 KFM83246.1 - 0.0029 17.2 0.2 0.0069 16.0 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_26 PF13443.6 KFM83246.1 - 0.0035 17.8 0.3 0.6 10.6 0.2 2.3 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain PAX PF00292.18 KFM83246.1 - 0.023 14.6 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain HTH_24 PF13412.6 KFM83246.1 - 0.046 13.3 1.1 1.2 8.7 0.0 2.5 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KFM83246.1 - 0.047 13.7 1.7 0.44 10.6 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KFM83246.1 - 0.049 13.5 2.6 0.67 9.9 0.1 2.8 2 1 1 3 3 3 0 MarR family HTH_21 PF13276.6 KFM83246.1 - 0.11 12.6 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 HTH-like domain HTH_7 PF02796.15 KFM83246.1 - 0.39 10.8 2.5 0.58 10.3 0.2 2.3 3 1 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KFM83247.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM83247.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM83247.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM83247.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM83247.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Kazal_2 PF07648.15 KFM83248.1 - 2.8e-09 37.0 1.8 4.5e-09 36.3 1.8 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFM83248.1 - 1.2e-05 25.3 3.7 2.9e-05 24.0 3.7 1.7 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain RNA_pol PF00940.19 KFM83249.1 - 1.1e-59 202.4 0.0 1.2e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Myb_DNA-bind_5 PF13873.6 KFM83250.1 - 0.00018 21.5 0.0 0.00022 21.2 0.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PP2C PF00481.21 KFM83251.1 - 0.005 16.5 0.0 0.0052 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Nup188_C PF18378.1 KFM83251.1 - 0.049 12.4 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain Daxx PF03344.15 KFM83252.1 - 0.0076 16.3 1.1 0.012 15.6 0.2 1.9 2 0 0 2 2 2 1 Daxx N-terminal Rassf1C-interacting domain MADF_DNA_bdg PF10545.9 KFM83253.1 - 8.8e-19 67.6 2.2 1.7e-18 66.7 0.6 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 KFM83253.1 - 2.4e-08 33.7 4.8 2.9e-08 33.4 2.0 2.6 3 0 0 3 3 3 1 BESS motif LemA PF04011.12 KFM83256.1 - 0.026 14.4 0.1 0.026 14.4 0.1 1.0 1 0 0 1 1 1 0 LemA family zf-H2C2_2 PF13465.6 KFM83257.1 - 3e-41 138.0 19.1 2.6e-09 37.1 0.3 5.1 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83257.1 - 4.6e-24 83.5 26.5 2.3e-06 27.8 0.6 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83257.1 - 1e-17 63.3 26.9 0.00028 21.5 0.6 4.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KFM83257.1 - 3.5e-13 49.4 31.9 0.001 19.4 0.9 5.2 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM83257.1 - 4.3e-11 42.4 7.7 0.011 15.5 0.0 4.5 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM83257.1 - 1.4e-09 37.7 27.5 0.0049 16.8 0.4 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM83257.1 - 3.4e-08 33.5 18.7 0.098 13.0 0.2 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFM83257.1 - 4.5e-06 26.4 9.4 1.3 9.0 0.1 5.1 5 0 0 5 5 5 3 zinc-finger of a C2HC-type Tox-HNH-HHH PF15637.6 KFM83257.1 - 6.4e-06 26.3 0.3 0.45 10.7 0.0 2.9 1 1 2 3 3 3 3 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2H2_11 PF16622.5 KFM83257.1 - 7.5e-06 25.6 11.2 0.27 11.0 0.3 4.2 4 0 0 4 4 4 2 zinc-finger C2H2-type TRAF6_Z2 PF18048.1 KFM83257.1 - 3.8e-05 23.7 14.8 0.15 12.2 1.4 4.3 4 0 0 4 4 4 2 TNF receptor-associated factor 6 zinc finger 2 ADK_lid PF05191.14 KFM83257.1 - 0.00012 22.0 9.7 0.14 12.2 2.0 3.6 1 1 3 4 4 4 2 Adenylate kinase, active site lid GAGA PF09237.11 KFM83257.1 - 0.00037 20.3 5.6 0.64 9.9 0.3 3.5 1 1 3 4 4 4 2 GAGA factor zf-CHCC PF10276.9 KFM83257.1 - 0.00096 19.2 1.5 52 4.0 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger domain DUF2256 PF10013.9 KFM83257.1 - 0.001 19.1 8.9 10 6.3 0.1 4.7 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 KFM83257.1 - 0.0017 18.4 17.6 0.011 15.8 10.2 2.9 1 1 2 3 3 3 2 FYVE zinc finger zf-DBF PF07535.12 KFM83257.1 - 0.0065 16.6 13.0 6 7.1 0.1 4.7 5 0 0 5 5 5 0 DBF zinc finger zf-C2H2_9 PF16293.5 KFM83257.1 - 0.0078 16.0 12.3 3.7 7.5 0.1 4.0 1 1 3 4 4 4 1 C2H2 type zinc-finger (1 copy) C1_1 PF00130.22 KFM83257.1 - 0.0082 16.0 17.9 2.3 8.2 5.7 4.0 1 1 2 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) BolA PF01722.18 KFM83257.1 - 0.022 15.1 0.8 0.85 9.9 0.1 2.8 1 1 2 3 3 3 0 BolA-like protein zf-MYST PF17772.1 KFM83257.1 - 0.024 14.2 9.8 14 5.4 0.1 4.1 2 2 2 4 4 4 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 KFM83257.1 - 0.045 14.1 21.2 1.6 9.1 0.9 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-HIT PF04438.16 KFM83257.1 - 0.048 13.5 16.5 7.4 6.5 1.1 4.4 4 0 0 4 4 4 0 HIT zinc finger zf-SNAP50_C PF12251.8 KFM83257.1 - 0.061 13.0 13.0 0.45 10.2 4.2 2.6 1 1 3 4 4 4 0 snRNA-activating protein of 50kDa MW C terminal C5HCH PF17982.1 KFM83257.1 - 0.066 13.4 18.0 3.8 7.7 1.2 4.6 4 1 1 5 5 4 0 NSD Cys-His rich domain PqqA PF08042.11 KFM83257.1 - 0.072 13.2 0.6 1.9e+02 2.3 0.0 4.2 5 0 0 5 5 4 0 PqqA family zf-Dof PF02701.15 KFM83257.1 - 0.091 12.9 5.8 16 5.8 0.0 3.5 1 1 3 4 4 3 0 Dof domain, zinc finger zf_UBZ PF18439.1 KFM83257.1 - 0.17 11.5 15.4 9.3 5.9 0.1 4.5 5 0 0 5 5 4 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 KFM83257.1 - 0.19 11.8 15.0 15 5.7 0.2 4.6 5 0 0 5 5 5 0 XPA protein N-terminal zf-Sec23_Sec24 PF04810.15 KFM83257.1 - 0.21 11.7 12.4 14 5.8 0.2 4.3 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger zf-FPG_IleRS PF06827.14 KFM83257.1 - 0.28 11.1 13.6 28 4.7 0.1 4.8 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS DUF4764 PF15961.5 KFM83257.1 - 0.38 9.4 7.8 5.9 5.5 4.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) DUF5330 PF17264.2 KFM83257.1 - 0.54 10.3 8.9 22 5.1 0.2 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5330) zinc_ribbon_15 PF17032.5 KFM83257.1 - 0.8 10.5 12.7 1.9 9.3 1.1 2.5 1 1 2 3 3 3 0 zinc-ribbon family OSTMP1 PF09777.9 KFM83257.1 - 1.1 8.6 11.4 1.3 8.4 4.0 2.7 1 1 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor C1_4 PF07975.12 KFM83257.1 - 1.3 9.3 13.1 24 5.3 8.6 3.1 2 1 2 4 4 4 0 TFIIH C1-like domain zf-RRN7 PF11781.8 KFM83257.1 - 1.4 8.7 10.1 47 3.8 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RRPl_C4 PF17026.5 KFM83257.1 - 1.6 8.9 11.9 3.7 7.7 7.5 2.3 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Vps39_2 PF10367.9 KFM83257.1 - 2.1 8.8 18.5 9.5 6.7 1.1 4.3 1 1 3 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf-Paramyx-P PF13008.7 KFM83257.1 - 2.7 7.5 12.9 33 4.0 0.0 4.4 5 0 0 5 5 5 0 Zinc-binding domain of Paramyxoviridae V protein HNH_5 PF14279.6 KFM83257.1 - 3.8 7.4 19.6 8.1 6.4 0.3 4.3 3 2 1 4 4 4 0 HNH endonuclease zf-trcl PF13451.6 KFM83257.1 - 4.2 7.4 12.5 45 4.1 0.2 4.2 4 0 0 4 4 4 0 Probable zinc-ribbon domain FYDLN_acid PF09538.10 KFM83257.1 - 4.2 8.1 7.2 32 5.3 0.1 3.6 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-H2C2_2 PF13465.6 KFM83258.1 - 4.2e-50 166.0 41.8 5.1e-09 36.2 1.6 6.3 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83258.1 - 9.9e-33 110.8 58.5 1.7e-06 28.2 1.7 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83258.1 - 6.8e-21 73.2 52.8 0.0011 19.6 1.0 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFM83258.1 - 9.9e-21 73.4 44.8 0.0015 18.9 0.4 6.4 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83258.1 - 1.3e-14 53.7 42.9 0.0006 19.7 0.7 7.6 7 1 0 7 7 7 6 C2H2-type zinc finger ADK_lid PF05191.14 KFM83258.1 - 1.4e-10 41.0 11.9 0.015 15.3 0.5 4.7 4 2 0 4 4 4 3 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 KFM83258.1 - 7.3e-10 38.9 34.8 0.18 12.1 0.5 6.7 6 1 0 6 6 6 5 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 KFM83258.1 - 3.3e-07 30.3 17.1 3.9 7.7 0.2 6.2 6 0 0 6 6 6 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-CHCC PF10276.9 KFM83258.1 - 2e-06 27.7 3.3 25 5.0 0.0 6.0 6 0 0 6 6 6 0 Zinc-finger domain Tox-HNH-HHH PF15637.6 KFM83258.1 - 0.00013 22.0 1.5 0.12 12.5 0.0 3.3 1 1 1 3 3 3 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif Prok-RING_1 PF14446.6 KFM83258.1 - 0.00029 20.7 22.8 0.71 9.8 0.2 6.1 6 0 0 6 6 6 2 Prokaryotic RING finger family 1 zf-C2H2_11 PF16622.5 KFM83258.1 - 0.00041 20.1 30.4 1.2 9.0 0.5 7.0 7 0 0 7 7 7 2 zinc-finger C2H2-type C1_1 PF00130.22 KFM83258.1 - 0.00099 19.0 31.1 2 8.4 0.6 6.1 1 1 4 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) BolA PF01722.18 KFM83258.1 - 0.001 19.3 5.8 7 7.0 0.1 4.0 1 1 3 4 4 4 0 BolA-like protein zf-Dof PF02701.15 KFM83258.1 - 0.0012 19.0 17.8 0.66 10.2 0.1 5.2 1 1 5 6 6 6 2 Dof domain, zinc finger zf-RRPl_C4 PF17026.5 KFM83258.1 - 0.0013 18.8 19.6 0.0091 16.1 6.8 2.4 1 1 1 2 2 2 2 Putative ribonucleoprotein zinc-finger pf C4 type YyzF PF14116.6 KFM83258.1 - 0.0026 17.7 16.9 3.4 7.8 0.1 5.9 6 0 0 6 6 6 1 YyzF-like protein GAGA PF09237.11 KFM83258.1 - 0.0027 17.5 13.0 0.52 10.2 0.4 4.7 2 2 3 6 6 6 2 GAGA factor FYVE PF01363.21 KFM83258.1 - 0.0064 16.6 28.9 0.5 10.6 6.4 3.8 1 1 2 3 3 3 1 FYVE zinc finger C5HCH PF17982.1 KFM83258.1 - 0.0083 16.3 22.0 8.7 6.6 1.5 6.1 6 0 0 6 6 6 0 NSD Cys-His rich domain zf-C2H2_9 PF16293.5 KFM83258.1 - 0.017 15.0 20.7 1.9 8.4 0.7 5.7 2 1 5 7 7 6 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM83258.1 - 0.044 14.5 21.9 0.99 10.2 3.8 3.3 1 1 2 3 3 3 0 zinc-ribbon family zf-HIT PF04438.16 KFM83258.1 - 0.053 13.4 29.2 4.7 7.2 0.5 6.3 6 0 0 6 6 6 0 HIT zinc finger zf-FPG_IleRS PF06827.14 KFM83258.1 - 0.076 12.9 11.3 51 3.9 0.1 5.3 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS zf-C2HC_2 PF13913.6 KFM83258.1 - 0.13 12.2 22.0 9.5 6.2 0.1 6.5 6 0 0 6 6 6 0 zinc-finger of a C2HC-type HNH_5 PF14279.6 KFM83258.1 - 0.21 11.5 32.3 4.1 7.3 4.2 6.0 2 2 4 6 6 6 0 HNH endonuclease zf-RING_UBOX PF13445.6 KFM83258.1 - 0.48 10.5 11.3 30 4.7 0.0 5.5 5 1 1 6 6 6 0 RING-type zinc-finger zf_UBZ PF18439.1 KFM83258.1 - 1.2 8.7 23.7 13 5.5 0.3 6.2 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM83258.1 - 1.7 8.3 26.3 3.4 7.4 0.2 6.0 1 1 5 6 6 6 0 MYST family zinc finger domain zf-trcl PF13451.6 KFM83258.1 - 2.7 7.9 25.8 8.9 6.3 0.0 6.0 6 0 0 6 6 6 0 Probable zinc-ribbon domain XPA_N PF01286.18 KFM83258.1 - 3 8.0 21.7 34 4.6 0.3 6.0 6 0 0 6 6 6 0 XPA protein N-terminal zf-C2H2_2 PF12756.7 KFM83258.1 - 5.8 7.3 37.4 1.7 9.0 0.9 5.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-RRN7 PF11781.8 KFM83258.1 - 6.4 6.6 16.0 40 4.0 0.1 5.6 6 0 0 6 6 6 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf_PR_Knuckle PF18445.1 KFM83258.1 - 7.5 6.5 13.5 38 4.2 0.3 5.5 6 0 0 6 6 6 0 PR zinc knuckle motif eIF_4EBP PF05456.11 KFM83260.1 - 0.012 15.5 0.1 0.012 15.5 0.1 3.2 4 0 0 4 4 4 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Cwf_Cwc_15 PF04889.12 KFM83261.1 - 1.5e-14 54.4 0.1 1.6e-14 54.3 0.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-H2C2_2 PF13465.6 KFM83263.1 - 1e-91 297.6 90.1 1.5e-09 37.8 1.1 14.1 14 0 0 14 14 14 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83263.1 - 4.3e-50 165.5 98.3 3.6e-06 27.1 0.2 13.9 14 0 0 14 14 14 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83263.1 - 7.6e-42 138.4 93.2 0.0013 19.3 0.2 13.4 14 0 0 14 14 14 12 C2H2-type zinc finger zf-met PF12874.7 KFM83263.1 - 1.9e-28 98.0 87.9 0.0012 19.1 0.1 13.3 13 0 0 13 13 13 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83263.1 - 6.8e-20 70.8 67.8 0.014 15.6 0.1 13.0 12 1 1 13 13 13 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83263.1 - 1.2e-17 63.4 80.8 0.00052 19.9 0.1 13.6 13 1 0 13 13 13 10 C2H2-type zinc finger BolA PF01722.18 KFM83263.1 - 1.3e-07 31.8 4.9 12 6.2 0.1 7.5 2 2 5 7 7 7 0 BolA-like protein ADK_lid PF05191.14 KFM83263.1 - 5.2e-05 23.1 48.6 0.1 12.6 0.7 8.4 6 2 4 10 10 10 4 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KFM83263.1 - 0.00019 21.2 40.3 8.2 6.4 0.0 11.0 12 0 0 12 12 11 1 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFM83263.1 - 0.0012 18.5 50.0 3 7.5 0.1 11.5 8 4 4 12 12 12 3 MYST family zinc finger domain Tox-HNH-HHH PF15637.6 KFM83263.1 - 0.0012 19.0 3.5 63 3.8 0.0 5.3 1 1 6 8 8 8 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif FYVE PF01363.21 KFM83263.1 - 0.043 13.9 57.7 6.4 7.0 7.2 7.6 2 2 5 7 7 7 0 FYVE zinc finger zf_UBZ PF18439.1 KFM83263.1 - 0.13 11.9 55.6 8.8 6.0 0.3 12.5 13 0 0 13 13 13 0 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 KFM83263.1 - 0.32 11.2 45.7 7 6.9 0.1 11.7 13 0 0 13 13 13 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 KFM83263.1 - 0.4 10.5 28.5 4.8 7.1 0.0 8.9 3 2 8 12 12 12 0 GAGA factor C1_1 PF00130.22 KFM83263.1 - 0.43 10.5 64.6 3.3 7.7 0.4 12.0 3 3 9 12 12 12 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 KFM83263.1 - 1 9.5 44.1 0.79 9.9 4.8 5.5 2 2 2 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type PqqA PF08042.11 KFM83263.1 - 1.3 9.1 10.2 4.1e+02 1.2 0.1 7.8 11 0 0 11 11 11 0 PqqA family Ribosomal_L35p PF01632.19 KFM83263.1 - 4.2 7.9 7.9 25 5.5 0.1 5.3 6 2 2 8 8 6 0 Ribosomal protein L35 zf-C2H2_11 PF16622.5 KFM83263.1 - 5.8 6.8 54.9 1.4 8.8 0.2 10.7 12 0 0 12 12 11 0 zinc-finger C2H2-type zf-DBF PF07535.12 KFM83263.1 - 7.4 6.8 46.3 17 5.6 0.1 10.5 12 0 0 12 12 12 0 DBF zinc finger zf-H2C2_2 PF13465.6 KFM83264.1 - 0.01 16.3 0.3 0.82 10.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83264.1 - 0.071 13.6 5.5 0.16 12.5 0.1 3.3 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83264.1 - 1.7 9.7 6.9 3.6 8.7 0.5 3.2 2 1 1 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFM83267.1 - 5.9e-36 121.3 36.4 8e-09 35.5 2.6 5.1 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83267.1 - 1.8e-20 72.2 46.7 7.8e-05 22.9 5.4 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83267.1 - 1.4e-14 53.5 43.8 0.00074 20.1 3.7 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM83267.1 - 4.4e-10 39.1 16.7 0.0054 16.5 0.2 4.5 4 0 0 4 4 4 4 C2H2-type zinc-finger domain zf-met PF12874.7 KFM83267.1 - 2.2e-08 34.2 37.3 0.0041 17.4 0.6 5.2 5 0 0 5 5 5 3 Zinc-finger of C2H2 type GAGA PF09237.11 KFM83267.1 - 5.7e-08 32.5 9.2 0.04 13.7 0.0 4.7 1 1 4 5 5 5 4 GAGA factor zf-C2H2_6 PF13912.6 KFM83267.1 - 2e-05 24.4 38.8 0.0044 17.0 2.4 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFM83267.1 - 0.00014 21.6 11.7 1.9 8.4 0.6 4.2 1 1 3 4 4 4 3 C2H2 type zinc-finger (1 copy) zf-FPG_IleRS PF06827.14 KFM83267.1 - 0.0023 17.7 13.2 9.5 6.2 0.2 5.2 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS TRAF6_Z2 PF18048.1 KFM83267.1 - 0.0059 16.7 13.9 0.077 13.1 0.5 3.5 4 0 0 4 4 4 2 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_jaz PF12171.8 KFM83267.1 - 0.014 15.7 32.4 0.028 14.7 0.7 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFM83267.1 - 0.046 13.5 1.5 0.046 13.5 1.5 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type BolA PF01722.18 KFM83267.1 - 0.061 13.6 3.9 0.66 10.3 0.6 3.0 1 1 2 3 3 3 0 BolA-like protein UvsY PF11056.8 KFM83267.1 - 0.1 12.9 0.2 1.3 9.4 0.0 2.0 1 1 1 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY zf-DBF PF07535.12 KFM83267.1 - 0.12 12.5 29.6 0.48 10.6 1.5 5.2 5 0 0 5 5 5 0 DBF zinc finger zf-MYST PF17772.1 KFM83267.1 - 0.17 11.5 28.8 0.28 10.8 0.8 5.0 1 1 4 5 5 5 0 MYST family zinc finger domain zf-C2H2_8 PF15909.5 KFM83267.1 - 0.23 11.8 19.6 0.28 11.5 0.2 3.4 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-Paramyx-P PF13008.7 KFM83267.1 - 0.61 9.6 13.4 19 4.8 0.0 4.9 5 0 0 5 5 5 0 Zinc-binding domain of Paramyxoviridae V protein DUF2757 PF10955.8 KFM83267.1 - 0.75 10.1 20.6 6.3 7.1 0.2 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2757) Zf_RING PF16744.5 KFM83267.1 - 0.88 9.7 24.2 12 6.1 1.1 4.9 1 1 3 4 4 4 0 KIAA1045 RING finger FYVE PF01363.21 KFM83267.1 - 0.94 9.7 25.6 0.48 10.6 14.7 3.0 1 1 1 2 2 2 0 FYVE zinc finger PqqA PF08042.11 KFM83267.1 - 1.8 8.7 3.9 1.7e+02 2.5 0.0 4.1 5 0 0 5 5 5 0 PqqA family zf-HIT PF04438.16 KFM83267.1 - 1.8 8.5 24.2 5 7.1 1.5 5.1 5 0 0 5 5 5 0 HIT zinc finger zinc_ribbon_15 PF17032.5 KFM83267.1 - 2.5 8.9 19.6 1.1 10.1 1.7 2.8 1 1 2 3 3 3 0 zinc-ribbon family DUF5330 PF17264.2 KFM83267.1 - 3.7 7.6 14.7 11 6.2 0.2 4.5 5 0 0 5 5 5 0 Family of unknown function (DUF5330) PHD PF00628.29 KFM83267.1 - 7.7 6.5 21.1 12 5.9 11.4 3.8 2 1 1 3 3 3 0 PHD-finger zf-C2H2_2 PF12756.7 KFM83267.1 - 8 6.9 31.7 1.2 9.6 3.4 4.3 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM83268.1 - 8.1e-68 222.0 66.7 9.6e-09 35.3 0.4 10.3 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83268.1 - 1.5e-47 157.5 85.8 1.4e-06 28.4 2.0 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83268.1 - 2.8e-34 114.8 82.9 0.00092 19.9 1.5 10.2 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM83268.1 - 6.4e-25 86.8 80.3 0.0032 17.8 1.5 10.3 10 0 0 10 10 10 10 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM83268.1 - 3.1e-15 55.6 51.4 6.2e-05 22.7 0.0 9.9 10 0 0 10 10 9 7 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFM83268.1 - 7.9e-10 38.5 70.0 0.086 12.9 0.2 11.3 11 0 0 11 11 11 8 C2H2-type zinc finger BolA PF01722.18 KFM83268.1 - 5.9e-09 36.1 11.6 0.35 11.2 0.0 6.6 1 1 6 7 7 7 3 BolA-like protein zf-C2HC_2 PF13913.6 KFM83268.1 - 4.7e-08 32.7 42.0 1.1 9.2 0.1 10.1 10 0 0 10 10 10 5 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFM83268.1 - 2.1e-06 27.9 66.4 0.095 13.0 0.4 10.6 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFM83268.1 - 2.8e-05 23.8 24.1 1.4 8.8 0.1 7.7 2 2 7 9 9 9 4 GAGA factor Tox-HNH-HHH PF15637.6 KFM83268.1 - 0.0016 18.6 0.6 4.7 7.4 0.1 4.1 1 1 3 5 5 5 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Sec23_Sec24 PF04810.15 KFM83268.1 - 0.0022 18.0 39.4 2.2 8.4 0.0 9.9 8 2 2 10 10 10 1 Sec23/Sec24 zinc finger PqqA PF08042.11 KFM83268.1 - 0.023 14.7 1.9 3.8e+02 1.3 0.0 5.6 6 0 0 6 6 6 0 PqqA family ADK_lid PF05191.14 KFM83268.1 - 0.026 14.5 36.1 0.058 13.4 0.7 6.0 5 1 0 5 5 5 0 Adenylate kinase, active site lid BHD_1 PF10403.9 KFM83268.1 - 0.053 13.4 1.9 4.3 7.2 0.0 4.4 5 0 0 5 5 5 0 Rad4 beta-hairpin domain 1 Mga PF05043.13 KFM83268.1 - 0.18 12.4 1.0 17 6.1 0.0 3.6 3 1 1 4 4 4 0 Mga helix-turn-helix domain FYVE PF01363.21 KFM83268.1 - 0.42 10.8 62.8 0.45 10.7 7.3 6.7 1 1 4 5 5 4 0 FYVE zinc finger C5HCH PF17982.1 KFM83268.1 - 1.6 8.9 54.9 4.5 7.5 3.1 9.7 5 2 5 10 10 10 0 NSD Cys-His rich domain zf-MYST PF17772.1 KFM83268.1 - 2.4 7.8 46.4 2.1 8.0 0.5 9.6 3 1 7 10 10 10 0 MYST family zinc finger domain Flag1_repress PF03614.13 KFM83268.1 - 2.6 7.8 4.6 16 5.2 0.2 3.0 1 1 2 3 3 3 0 Repressor of phase-1 flagellin zf-RRPl_C4 PF17026.5 KFM83268.1 - 4.6 7.4 44.5 16 5.7 8.4 4.6 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type DDE_3 PF13358.6 KFM83269.1 - 1e-09 38.3 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PRiA4_ORF3 PF07929.11 KFM83269.1 - 0.15 11.7 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein Cullin PF00888.22 KFM83270.1 - 1.4e-07 30.6 0.7 1.4e-07 30.6 0.7 1.0 1 0 0 1 1 1 1 Cullin family GA-like PF17573.2 KFM83270.1 - 0.016 15.1 0.5 0.031 14.2 0.3 1.6 1 1 0 1 1 1 0 GA-like domain UBA_4 PF14555.6 KFM83270.1 - 0.14 12.0 0.1 14 5.6 0.0 2.2 1 1 1 2 2 2 0 UBA-like domain DDE_3 PF13358.6 KFM83272.1 - 0.00093 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease EF-hand_13 PF17958.1 KFM83272.1 - 0.031 14.1 0.2 0.08 12.8 0.1 1.7 1 1 1 2 2 2 0 EF-hand domain Alpha-amylase_C PF02806.18 KFM83273.1 - 8.3e-12 45.4 0.3 1e-10 41.9 0.1 2.5 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KFM83273.1 - 1.5e-08 34.6 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain HTH_Tnp_Tc3_2 PF01498.18 KFM83274.1 - 2.6e-16 59.6 2.8 4.8e-16 58.8 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM83274.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM83274.1 - 1.6e-07 30.9 1.2 6.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM83274.1 - 0.0022 17.7 0.6 0.0066 16.2 0.6 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM83274.1 - 1.7 9.3 15.7 0.1 13.2 1.9 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Arf PF00025.21 KFM83275.1 - 4.8e-14 52.2 0.2 5e-14 52.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFM83275.1 - 0.00075 18.8 0.1 0.00075 18.8 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 KFM83275.1 - 0.0023 17.4 0.0 0.0024 17.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFM83275.1 - 0.0052 16.8 0.0 0.0058 16.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 KFM83275.1 - 0.0087 15.5 0.0 0.0087 15.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 KFM83275.1 - 0.021 15.0 0.0 0.022 14.9 0.0 1.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KFM83275.1 - 0.026 14.1 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KFM83275.1 - 0.028 15.0 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFM83275.1 - 0.031 14.0 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 KFM83275.1 - 0.095 12.7 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFM83275.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KFM83275.1 - 0.17 11.2 0.0 0.17 11.2 0.0 1.0 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 KFM83275.1 - 0.18 12.0 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain GIY-YIG PF01541.24 KFM83277.1 - 0.0014 18.8 0.7 0.005 17.1 0.1 2.0 2 0 0 2 2 2 1 GIY-YIG catalytic domain Kinin PF08260.11 KFM83277.1 - 4.9 8.0 6.0 3.9 8.3 0.9 2.7 2 0 0 2 2 2 0 Insect kinin peptide zf-C2H2 PF00096.26 KFM83278.1 - 2.1e-07 31.0 4.3 2.2e-07 30.9 2.2 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM83278.1 - 1.6e-06 28.3 6.8 0.00026 21.3 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM83278.1 - 6.1e-05 23.5 2.6 0.00022 21.8 1.6 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KFM83278.1 - 0.00025 21.3 2.0 0.00025 21.3 2.0 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM83278.1 - 0.0042 16.8 2.4 0.0077 16.0 2.4 1.6 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM83278.1 - 0.0042 17.3 0.7 0.0042 17.3 0.7 2.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83278.1 - 0.036 14.1 2.1 0.51 10.4 1.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Retrotran_gag_2 PF14223.6 KFM83280.1 - 2.9e-10 39.9 0.3 3.4e-10 39.7 0.3 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2 PF00096.26 KFM83281.1 - 5.3e-09 36.0 25.1 0.0012 19.1 2.1 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-BED PF02892.15 KFM83281.1 - 2.3e-07 30.7 20.9 0.0037 17.2 2.1 3.4 2 1 1 3 3 3 3 BED zinc finger zf-H2C2_2 PF13465.6 KFM83281.1 - 1.4e-06 28.4 14.1 0.033 14.6 1.6 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM83281.1 - 8e-06 26.3 27.8 0.028 15.3 1.9 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KFM83281.1 - 0.0016 18.7 1.5 2.7 8.3 0.0 2.9 2 1 0 2 2 2 2 zinc-ribbon zf-C2H2_8 PF15909.5 KFM83281.1 - 0.0018 18.5 15.3 0.28 11.5 4.5 2.6 1 1 1 2 2 2 2 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KFM83281.1 - 0.0028 17.7 8.1 0.084 13.0 1.6 3.1 2 1 0 2 2 2 1 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KFM83281.1 - 0.0029 17.5 11.0 1.1 9.2 0.1 3.3 2 1 1 3 3 3 1 zinc-ribbon domain zf-C2H2_jaz PF12171.8 KFM83281.1 - 0.0062 16.8 14.2 0.22 11.8 0.4 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM83281.1 - 0.012 16.0 0.5 0.012 16.0 0.5 3.6 4 0 0 4 4 3 0 Zinc-finger of C2H2 type CpXC PF14353.6 KFM83281.1 - 0.015 15.3 7.0 0.92 9.6 0.4 3.2 1 1 2 3 3 3 0 CpXC protein PyrI_C PF02748.15 KFM83281.1 - 0.017 15.0 4.7 9.4 6.2 0.1 3.4 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.6 KFM83281.1 - 0.019 15.0 7.2 1.6 8.9 0.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM83281.1 - 0.033 14.1 19.3 0.22 11.5 2.7 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFM83281.1 - 0.046 13.8 6.9 1.9 8.7 0.9 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_recom PF13408.6 KFM83281.1 - 0.099 13.2 15.8 0.41 11.2 0.5 3.2 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-CRD PF17979.1 KFM83281.1 - 0.1 12.7 14.2 1.5 8.9 5.6 2.5 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions LIM PF00412.22 KFM83281.1 - 0.13 12.5 14.8 3.7 7.9 7.5 3.0 2 1 0 2 2 2 0 LIM domain Mut7-C PF01927.16 KFM83281.1 - 0.18 11.9 7.7 0.28 11.3 0.2 3.0 1 1 2 3 3 3 0 Mut7-C RNAse domain Zn_Tnp_IS1595 PF12760.7 KFM83281.1 - 0.19 11.7 10.7 12 5.9 0.1 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 KFM83281.1 - 0.2 11.1 8.0 2.1 7.9 0.2 2.8 3 0 0 3 3 2 0 zinc-ribbon domain C1_4 PF07975.12 KFM83281.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.0 1 1 1 3 3 3 0 TFIIH C1-like domain zf-LSD1 PF06943.12 KFM83281.1 - 0.27 11.1 8.6 2.1 8.3 0.3 2.7 3 0 0 3 3 2 0 LSD1 zinc finger zf_UBZ PF18439.1 KFM83281.1 - 0.35 10.5 9.4 12 5.6 0.2 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 KFM83281.1 - 0.35 10.9 8.3 21 5.3 0.2 3.6 3 0 0 3 3 3 0 XPA protein N-terminal c-SKI_SMAD_bind PF08782.10 KFM83281.1 - 0.4 11.0 15.9 4.7 7.5 2.1 3.3 1 1 2 3 3 3 0 c-SKI Smad4 binding domain DNA_RNApol_7kD PF03604.13 KFM83281.1 - 0.4 10.4 5.8 16 5.3 0.2 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_15 PF17032.5 KFM83281.1 - 0.51 11.1 11.7 0.11 13.3 2.4 2.4 1 1 2 3 3 3 0 zinc-ribbon family VATC PF18716.1 KFM83281.1 - 0.68 9.8 14.4 12 5.9 0.2 3.9 3 2 0 3 3 3 0 Vms1-associating treble clef domain HypA PF01155.19 KFM83281.1 - 1.3 9.0 9.8 4.7 7.3 3.1 2.3 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 KFM83281.1 - 1.4 9.0 12.7 1.6 8.7 3.9 3.1 2 1 0 3 3 3 0 zinc-ribbons Rubredoxin_2 PF18073.1 KFM83281.1 - 2.6 7.8 11.2 18 5.1 0.2 3.3 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-trcl PF13451.6 KFM83281.1 - 2.8 7.9 10.7 26 4.8 0.1 3.6 3 1 0 3 3 3 0 Probable zinc-ribbon domain RIG-I_C-RD PF11648.8 KFM83281.1 - 3.3 8.0 9.5 14 6.0 3.2 2.8 1 1 2 3 3 3 0 C-terminal domain of RIG-I Rhodanese_C PF12368.8 KFM83281.1 - 4.1 7.9 12.2 8.1 6.9 0.6 3.2 2 1 1 3 3 3 0 Rhodanase C-terminal ADD_ATRX PF17981.1 KFM83281.1 - 4.9 7.1 10.0 11 6.0 0.2 3.4 2 1 1 3 3 3 0 Cysteine Rich ADD domain Lar_restr_allev PF14354.6 KFM83281.1 - 5.5 7.4 8.2 11 6.5 0.3 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar IBR PF01485.21 KFM83281.1 - 9.1 6.6 19.0 10 6.4 2.5 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Terminase_GpA PF05876.12 KFM83281.1 - 9.2 4.7 9.9 1.1 7.8 4.0 1.9 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) DNA_pol_B_2 PF03175.13 KFM83282.1 - 0.00015 20.8 0.2 0.00023 20.1 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Endonuclease_7 PF02945.15 KFM83282.1 - 0.0016 18.4 0.6 0.0035 17.2 0.6 1.5 1 0 0 1 1 1 1 Recombination endonuclease VII CTU2 PF10288.9 KFM83282.1 - 0.034 14.4 0.2 0.064 13.5 0.2 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-CCHC_4 PF14392.6 KFM83283.1 - 0.27 11.0 15.3 0.18 11.6 2.0 2.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 KFM83283.1 - 0.7 9.8 15.4 4 7.4 2.9 3.6 3 0 0 3 3 3 0 Zinc knuckle HET PF06985.11 KFM83284.1 - 0.2 12.0 2.5 0.15 12.4 0.5 1.7 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) FidL_like PF15941.5 KFM83284.1 - 0.79 10.2 6.3 0.14 12.7 2.2 1.9 2 1 0 2 2 2 0 FidL-like putative membrane protein Dimer_Tnp_hAT PF05699.14 KFM83285.1 - 0.013 15.2 0.0 0.015 15.1 0.0 1.0 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DDE_Tnp_1_7 PF13843.6 KFM83286.1 - 5.3e-26 91.8 0.0 6.2e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 RVT_1 PF00078.27 KFM83286.1 - 0.0051 16.4 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_1 PF00036.32 KFM83287.1 - 8.6e-08 31.2 0.2 0.0049 16.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFM83287.1 - 1.3e-06 28.8 1.7 1.6e-06 28.4 1.7 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KFM83287.1 - 9.4e-05 22.2 2.9 0.0014 18.5 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM83287.1 - 0.00022 20.9 0.5 0.0052 16.6 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFM83287.1 - 0.00073 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.6 KFM83287.1 - 0.014 15.7 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_11 PF08976.11 KFM83287.1 - 0.022 15.6 0.0 0.029 15.3 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain zf-CCHC PF00098.23 KFM83288.1 - 0.013 15.6 0.8 0.013 15.6 0.8 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KFM83288.1 - 3.5 7.5 8.9 0.35 10.7 1.1 2.3 2 0 0 2 2 2 0 Zinc knuckle Cullin PF00888.22 KFM83290.1 - 1.4e-08 33.8 0.0 1.5e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Cullin family SWIM PF04434.17 KFM83291.1 - 0.0081 15.8 7.1 0.012 15.3 0.2 2.5 2 0 0 2 2 2 2 SWIM zinc finger DDE_3 PF13358.6 KFM83292.1 - 8.6e-17 61.3 0.1 9.5e-16 57.9 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM83292.1 - 6.7e-16 58.3 5.9 1.3e-15 57.4 5.9 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM83292.1 - 0.001 19.6 1.2 0.001 19.6 1.2 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM83292.1 - 0.0024 17.6 0.1 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM83292.1 - 0.017 15.2 0.1 0.064 13.4 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM83292.1 - 0.032 14.2 2.6 0.035 14.1 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix zf-C2H2 PF00096.26 KFM83293.1 - 3e-22 77.7 52.3 2.3e-05 24.6 5.5 7.1 6 1 1 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFM83293.1 - 2.1e-20 72.2 49.2 3.7e-07 30.3 1.9 7.6 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFM83293.1 - 1.4e-14 53.5 49.2 0.0053 17.5 4.0 7.3 6 1 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFM83293.1 - 2.3e-05 24.6 23.9 0.0035 17.6 1.7 4.0 2 1 2 4 4 4 3 C2H2-type zinc ribbon zf-met PF12874.7 KFM83293.1 - 0.011 16.1 1.9 0.011 16.1 1.9 7.1 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KFM83293.1 - 0.046 13.6 16.4 2 8.4 0.1 5.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type C1_4 PF07975.12 KFM83293.1 - 0.39 11.0 20.4 0.48 10.7 0.0 4.1 3 1 1 4 4 4 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 KFM83293.1 - 0.88 9.6 46.5 0.91 9.6 1.2 6.1 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFM83293.1 - 1.6 8.6 27.9 1.5 8.7 0.7 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type MULE PF10551.9 KFM83294.1 - 0.00015 22.1 0.3 0.0093 16.4 0.0 2.6 1 1 1 2 2 2 2 MULE transposase domain zf-C2H2_4 PF13894.6 KFM83295.1 - 2.2e-06 28.0 8.0 0.0083 16.9 0.6 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM83295.1 - 5.3e-05 23.5 11.9 0.001 19.4 0.9 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KFM83295.1 - 0.00064 19.4 4.9 0.047 13.5 0.5 2.7 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2HE PF16278.5 KFM83295.1 - 0.023 15.1 6.0 0.73 10.3 0.7 2.7 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 KFM83295.1 - 0.047 13.6 2.3 0.97 9.4 0.1 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 KFM83295.1 - 2.3 8.8 18.9 0.49 10.9 2.4 4.1 4 1 0 4 4 4 0 Zinc-finger double domain DUF3480 PF11979.8 KFM83296.1 - 8.7e-39 133.5 0.0 9.5e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) Ig_3 PF13927.6 KFM83296.1 - 0.084 13.5 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain SOCS_box PF07525.16 KFM83298.1 - 0.065 13.6 0.7 0.065 13.6 0.7 2.3 3 0 0 3 3 3 0 SOCS box HTH_Tnp_Tc3_2 PF01498.18 KFM83299.1 - 5.1e-16 58.7 3.5 5.8e-16 58.5 2.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM83299.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM83299.1 - 2.1e-07 30.6 1.2 7.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM83299.1 - 0.0028 17.4 0.6 0.0077 16.0 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM83299.1 - 2.5 8.8 15.6 0.12 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.6 KFM83301.1 - 5.7e-37 127.8 0.7 6.8e-37 127.6 0.7 1.1 1 0 0 1 1 1 1 Transposase IS4 Secretin_N_2 PF07655.13 KFM83301.1 - 0.12 13.0 0.9 0.21 12.2 0.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Mito_carr PF00153.27 KFM83302.1 - 5.4e-36 122.4 0.1 8.1e-21 73.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 KFM83302.1 - 0.11 11.6 0.1 2 7.5 0.0 2.4 2 1 1 3 3 3 0 Gammaproteobacterial serine protease zf-H2C2_2 PF13465.6 KFM83303.1 - 7.1e-56 184.3 67.0 2.5e-09 37.1 0.7 10.0 9 1 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83303.1 - 7.8e-43 142.6 81.0 1.2e-05 25.5 0.8 9.2 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83303.1 - 7.5e-28 94.8 75.8 0.001 19.7 0.6 9.2 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM83303.1 - 4.1e-21 74.7 73.8 0.00098 19.4 1.2 8.7 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83303.1 - 9.3e-15 54.2 57.6 0.0059 16.6 0.3 9.1 8 1 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM83303.1 - 2.3e-10 40.5 56.6 0.052 13.9 0.8 9.4 7 2 1 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-RRPl_C4 PF17026.5 KFM83303.1 - 1.5e-05 25.0 35.4 0.0053 16.8 8.6 3.9 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type zf-Sec23_Sec24 PF04810.15 KFM83303.1 - 9.5e-05 22.4 24.4 5.7 7.1 0.1 8.2 5 3 2 8 8 8 1 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KFM83303.1 - 0.00021 21.0 47.1 0.15 11.9 0.3 8.8 2 1 7 9 9 9 5 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFM83303.1 - 0.0019 18.0 17.9 0.61 9.9 0.0 6.2 2 1 4 7 7 7 2 GAGA factor zf-C2H2_11 PF16622.5 KFM83303.1 - 0.0019 17.9 57.3 0.088 12.6 0.7 8.8 9 0 0 9 9 9 4 zinc-finger C2H2-type ADK_lid PF05191.14 KFM83303.1 - 0.0022 18.0 26.6 0.015 15.3 1.2 5.6 6 0 0 6 6 6 2 Adenylate kinase, active site lid BolA PF01722.18 KFM83303.1 - 0.0042 17.3 18.6 0.033 14.5 0.5 5.5 1 1 3 5 5 5 1 BolA-like protein zf-H2C2_5 PF13909.6 KFM83303.1 - 0.014 15.1 67.7 0.22 11.3 0.3 9.6 10 0 0 10 10 8 0 C2H2-type zinc-finger domain DUF2256 PF10013.9 KFM83303.1 - 0.039 14.1 32.1 6.2 7.0 0.4 7.8 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KFM83303.1 - 0.29 11.5 65.8 0.69 10.3 1.7 8.0 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KFM83303.1 - 0.96 9.6 44.4 0.73 10.0 9.7 4.5 1 1 3 4 4 4 0 FYVE zinc finger DUF3268 PF11672.8 KFM83303.1 - 2.4 8.5 22.4 5.4 7.4 3.1 4.0 3 1 1 4 4 4 0 zinc-finger-containing domain zf-HIT PF04438.16 KFM83303.1 - 3.9 7.4 38.5 1.7 8.6 0.3 7.9 8 0 0 8 8 8 0 HIT zinc finger zinc_ribbon_15 PF17032.5 KFM83303.1 - 6.6 7.6 33.7 3 8.6 1.8 4.7 1 1 3 5 5 5 0 zinc-ribbon family zf-DBF PF07535.12 KFM83303.1 - 7.7 6.7 42.8 5.3 7.2 0.3 7.4 6 1 2 8 8 7 0 DBF zinc finger GAS2 PF02187.17 KFM83305.1 - 1.9e-33 114.3 0.9 3.9e-33 113.4 0.9 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_7 PF13499.6 KFM83305.1 - 4.5e-12 46.2 8.1 2e-08 34.5 1.9 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM83305.1 - 3.7e-11 41.7 7.7 2.2e-06 26.8 0.7 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFM83305.1 - 6.5e-11 41.3 2.1 2.7e-05 23.7 0.5 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFM83305.1 - 1.3e-09 37.1 7.5 1e-05 24.8 0.4 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFM83305.1 - 2.9e-06 27.0 3.7 0.00018 21.2 0.3 2.5 1 1 1 2 2 2 2 EF-hand domain pair DUF608 PF04685.13 KFM83305.1 - 0.097 11.8 0.5 0.61 9.2 0.3 1.9 1 1 1 2 2 2 0 Glycosyl-hydrolase family 116, catalytic region DUF4254 PF14063.6 KFM83305.1 - 0.13 12.1 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Exo_endo_phos PF03372.23 KFM83306.1 - 1.9e-10 40.7 0.1 3.5e-10 39.8 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFM83306.1 - 9.1e-10 38.4 3.2 2.9e-09 36.8 0.8 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC_4 PF14392.6 KFM83307.1 - 0.068 12.9 1.7 0.068 12.9 1.7 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 KFM83307.1 - 0.56 10.4 17.1 0.17 12.1 6.2 2.8 2 1 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 KFM83307.1 - 0.97 9.8 15.0 1.9 8.9 10.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DUF4186 PF13811.6 KFM83309.1 - 0.057 13.5 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) MADF_DNA_bdg PF10545.9 KFM83310.1 - 2.8e-19 69.2 1.3 3.5e-18 65.7 0.8 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 KFM83310.1 - 8e-10 38.4 0.1 2e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 BESS motif Myb_DNA-bind_4 PF13837.6 KFM83310.1 - 0.0025 18.2 0.2 0.006 16.9 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Aminotran_1_2 PF00155.21 KFM83311.1 - 1.3e-51 175.9 0.0 1.5e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFM83311.1 - 1.9e-06 27.1 0.0 5.4e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFM83311.1 - 0.019 14.3 0.0 0.061 12.6 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KFM83311.1 - 0.027 13.0 0.0 0.039 12.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KFM83311.1 - 0.031 13.6 0.1 0.061 12.6 0.1 1.4 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3481 PF11980.8 KFM83311.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Luteo_P1-P2 PF08467.10 KFM83311.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase DDE_Tnp_4 PF13359.6 KFM83313.1 - 4.7e-38 130.3 0.0 7.3e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM83313.1 - 5.8e-10 39.1 0.0 9.7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein NLRC4_HD2 PF17776.1 KFM83313.1 - 0.034 14.7 0.0 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 NLRC4 helical domain HD2 Trypsin PF00089.26 KFM83315.1 - 1.9e-64 217.5 0.0 2.3e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFM83315.1 - 1.5e-07 31.8 0.0 2.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Sushi PF00084.20 KFM83315.1 - 1.1e-05 25.9 1.3 3e-05 24.5 1.3 1.8 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Trypsin_2 PF13365.6 KFM83315.1 - 4.7e-05 24.3 0.0 7.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain zf-H2C2_2 PF13465.6 KFM83316.1 - 3.7e-64 210.5 54.9 4.8e-08 33.1 0.5 9.1 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83316.1 - 1.7e-40 135.3 77.9 6.5e-06 26.3 2.2 9.1 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83316.1 - 1.4e-28 97.0 72.6 0.0012 19.5 2.7 9.1 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 KFM83316.1 - 1.2e-21 76.3 73.1 0.0036 17.6 1.7 9.3 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83316.1 - 1.4e-15 57.1 54.9 0.011 16.0 0.2 9.3 9 0 0 9 9 9 9 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFM83316.1 - 6.6e-09 35.6 18.4 0.045 13.7 0.4 6.1 3 1 3 6 6 6 5 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM83316.1 - 8.8e-08 32.2 1.5 0.2 11.8 0.0 4.2 1 1 3 4 4 4 2 HNH/Endo VII superfamily nuclease toxin with a HHH motif C1_1 PF00130.22 KFM83316.1 - 0.00083 19.2 49.7 0.95 9.4 1.4 8.8 3 2 5 8 8 8 3 Phorbol esters/diacylglycerol binding domain (C1 domain) TRAF6_Z2 PF18048.1 KFM83316.1 - 0.00084 19.4 43.4 0.1 12.7 0.3 8.1 8 0 0 8 8 8 4 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_6 PF13912.6 KFM83316.1 - 0.00089 19.2 72.3 0.47 10.5 1.3 10.6 9 2 0 9 9 9 6 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM83316.1 - 0.00096 19.0 31.5 0.35 10.8 0.3 7.8 8 0 0 8 8 7 1 zinc-finger of a C2HC-type zf-DBF PF07535.12 KFM83316.1 - 0.0042 17.2 34.6 7 6.8 0.2 7.9 7 1 1 8 8 8 1 DBF zinc finger zf-RRPl_C4 PF17026.5 KFM83316.1 - 0.0065 16.6 34.9 0.028 14.5 7.0 4.2 1 1 3 4 4 4 2 Putative ribonucleoprotein zinc-finger pf C4 type NAD_kinase PF01513.21 KFM83316.1 - 0.025 13.8 0.2 7.4 5.7 0.0 3.1 1 1 2 3 3 3 0 ATP-NAD kinase DUF2256 PF10013.9 KFM83316.1 - 0.027 14.6 37.1 15 5.8 0.1 9.0 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Sec23_Sec24 PF04810.15 KFM83316.1 - 0.034 14.2 37.4 5.9 7.0 0.2 8.8 6 2 3 9 9 9 0 Sec23/Sec24 zinc finger Mga PF05043.13 KFM83316.1 - 0.039 14.5 1.7 21 5.8 0.0 3.9 4 1 0 4 4 3 0 Mga helix-turn-helix domain AvrPto PF11592.8 KFM83316.1 - 0.04 13.9 0.4 0.94 9.5 0.1 2.6 2 1 1 3 3 3 0 Central core of the bacterial effector protein AvrPto zf-Dof PF02701.15 KFM83316.1 - 0.22 11.7 25.1 1.1 9.5 0.3 5.1 2 2 3 5 5 5 0 Dof domain, zinc finger FYVE PF01363.21 KFM83316.1 - 0.59 10.3 49.0 92 3.3 18.7 5.0 1 1 2 3 3 3 0 FYVE zinc finger zf-CHCC PF10276.9 KFM83316.1 - 1.2 9.3 11.8 68 3.6 0.0 6.4 9 0 0 9 9 8 0 Zinc-finger domain zinc_ribbon_9 PF14369.6 KFM83316.1 - 2 8.8 0.0 2 8.8 0.0 7.0 8 1 0 8 8 8 0 zinc-ribbon zf-CCHC_4 PF14392.6 KFM83317.1 - 0.042 13.6 10.3 0.33 10.7 2.0 2.8 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 KFM83317.1 - 7.1 6.6 14.8 7.3 6.5 2.9 3.6 3 0 0 3 3 3 0 Zinc knuckle DDE_Tnp_1_7 PF13843.6 KFM83318.1 - 2.9e-72 243.9 0.1 3.4e-72 243.7 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 KFM83318.1 - 0.0019 17.9 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain PRiA4_ORF3 PF07929.11 KFM83319.1 - 2.1e-18 66.6 0.1 2.5e-18 66.4 0.1 1.0 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein DUF1838 PF08894.11 KFM83319.1 - 0.0015 18.3 0.4 0.0017 18.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) zf-C3HC4_3 PF13920.6 KFM83323.1 - 7e-12 45.0 11.3 1e-11 44.5 11.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM83323.1 - 4.9e-05 23.1 11.2 7.6e-05 22.5 11.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2039 PF10217.9 KFM83323.1 - 0.0052 17.1 5.3 0.0052 17.1 5.3 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zf-RING_5 PF14634.6 KFM83323.1 - 0.14 12.2 13.2 0.36 10.8 13.2 1.6 1 1 1 2 2 2 0 zinc-RING finger domain HEPN_RES_NTD1 PF18870.1 KFM83323.1 - 0.98 9.6 0.1 0.98 9.6 0.1 2.7 3 0 0 3 3 3 0 HEPN/RES N-terminal domain 1 zf-C2H2_jaz PF12171.8 KFM83324.1 - 3.5e-12 46.3 5.1 3.2e-05 24.1 1.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM83324.1 - 2.4e-10 40.4 9.8 7e-05 23.1 2.3 2.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFM83324.1 - 3.1e-07 30.6 4.0 0.006 16.9 0.2 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM83324.1 - 6.3e-05 23.5 1.3 0.3 12.0 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 KFM83324.1 - 0.00078 19.3 1.6 0.0057 16.5 0.2 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-C2H2_3rep PF18868.1 KFM83324.1 - 0.012 16.2 1.2 0.63 10.7 0.1 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-MYST PF17772.1 KFM83324.1 - 0.018 14.6 0.1 0.043 13.4 0.1 1.6 1 0 0 1 1 1 0 MYST family zinc finger domain zf-DBF PF07535.12 KFM83324.1 - 0.04 14.0 1.2 1.3 9.2 0.0 2.7 2 1 0 2 2 2 0 DBF zinc finger Evr1_Alr PF04777.13 KFM83324.1 - 0.089 13.3 1.5 0.3 11.6 0.3 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DUF629 PF04780.12 KFM83324.1 - 0.14 10.7 1.5 4.8 5.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_9 PF16293.5 KFM83324.1 - 0.16 11.9 4.0 1.3 8.9 0.2 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-U1 PF06220.12 KFM83324.1 - 0.57 10.0 4.4 0.22 11.3 0.4 2.1 2 0 0 2 2 2 0 U1 zinc finger Clusterin PF01093.17 KFM83325.1 - 0.0048 16.0 0.1 0.0053 15.9 0.1 1.0 1 0 0 1 1 1 1 Clusterin Jnk-SapK_ap_N PF09744.9 KFM83325.1 - 0.0065 16.7 1.6 0.0074 16.5 1.6 1.0 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 YscO PF07321.12 KFM83325.1 - 0.021 14.8 0.5 0.022 14.7 0.5 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO Coprogen_oxidas PF01218.18 KFM83325.1 - 0.037 12.7 0.2 0.037 12.7 0.2 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase GAPES4 PF17157.4 KFM83325.1 - 0.068 13.6 0.0 0.076 13.4 0.0 1.0 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Ribosomal_S13 PF00416.22 KFM83326.1 - 3.5e-57 192.3 2.5 4.1e-57 192.1 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PP28 PF10252.9 KFM83326.1 - 0.017 15.5 0.8 0.017 15.5 0.8 1.6 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 FbpA PF05833.11 KFM83326.1 - 0.032 13.0 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KFM83326.1 - 0.039 14.2 0.1 0.15 12.4 0.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif Transposase_1 PF01359.18 KFM83327.1 - 6.6e-14 51.5 0.4 1.4e-13 50.5 0.1 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 KFM83327.1 - 2.7e-09 36.9 0.0 4.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_10 PF12846.7 KFM83328.1 - 0.024 13.6 0.6 0.032 13.2 0.6 1.2 1 0 0 1 1 1 0 AAA-like domain RXLR PF16810.5 KFM83328.1 - 0.075 13.5 1.0 0.12 12.8 1.0 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity YqfQ PF14181.6 KFM83328.1 - 5.2 7.2 6.9 0.6 10.3 2.7 1.6 2 0 0 2 2 2 0 YqfQ-like protein DDE_3 PF13358.6 KFM83329.1 - 4.1e-16 59.0 0.1 4.3e-15 55.7 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM83329.1 - 7.6e-16 58.1 6.5 1.7e-15 57.0 6.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KFM83329.1 - 0.00084 19.9 1.5 0.00084 19.9 1.5 2.9 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KFM83329.1 - 0.0032 17.2 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.26 KFM83329.1 - 0.0098 16.1 1.0 0.25 11.6 0.0 3.4 3 1 1 4 4 4 1 Integrase core domain HTH_28 PF13518.6 KFM83329.1 - 0.019 15.1 0.1 0.074 13.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM83329.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn helix PMSR PF01625.21 KFM83330.1 - 1.9e-42 145.0 0.6 2.8e-42 144.5 0.6 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Vsr PF03852.15 KFM83330.1 - 0.05 13.5 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr HTH_Tnp_Tc3_2 PF01498.18 KFM83331.1 - 1.7e-18 66.6 1.5 3.1e-18 65.8 1.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM83331.1 - 4.3e-16 59.0 0.0 2.1e-15 56.8 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_7 PF02796.15 KFM83331.1 - 4.2e-05 23.5 0.3 0.026 14.6 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KFM83331.1 - 9.6e-05 22.9 3.1 0.00013 22.5 1.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM83331.1 - 0.00048 19.8 0.4 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KFM83331.1 - 0.009 16.1 1.8 0.96 9.6 0.1 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain Prefoldin_2 PF01920.20 KFM83332.1 - 7.9e-19 67.6 22.2 1.2e-18 67.0 22.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Rx_N PF18052.1 KFM83332.1 - 0.0086 16.3 3.8 0.0086 16.3 3.8 2.5 2 1 1 3 3 3 1 Rx N-terminal domain DUF148 PF02520.17 KFM83332.1 - 0.027 14.6 9.0 0.06 13.5 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 IL28A PF15177.6 KFM83332.1 - 0.067 13.0 7.2 0.89 9.4 0.3 2.1 1 1 1 2 2 2 0 Interleukin-28A YejG PF13989.6 KFM83332.1 - 0.22 12.0 4.7 0.22 12.0 0.6 2.1 2 0 0 2 2 2 0 YejG-like protein YtxH PF12732.7 KFM83332.1 - 0.29 11.7 4.4 6.7 7.3 4.4 2.2 1 1 0 1 1 1 0 YtxH-like protein L27 PF02828.16 KFM83332.1 - 0.74 9.6 10.8 0.055 13.2 4.0 2.2 2 0 0 2 2 2 0 L27 domain NPV_P10 PF05531.12 KFM83332.1 - 1.1 9.8 7.9 0.71 10.4 2.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ALIX_LYPXL_bnd PF13949.6 KFM83332.1 - 1.4 8.2 17.1 2.7 7.2 17.1 1.5 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF2408 PF10303.9 KFM83332.1 - 1.8 9.1 13.4 3.3 8.3 13.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1664 PF07889.12 KFM83332.1 - 2.3 8.3 13.8 1.2 9.1 5.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) KELK PF15796.5 KFM83332.1 - 3.7 8.1 21.3 0.31 11.5 2.2 2.2 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4559 PF15112.6 KFM83332.1 - 5.3 6.6 13.8 7.6 6.1 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) CREPT PF16566.5 KFM83332.1 - 6.1 7.0 16.6 4.3 7.5 7.6 2.1 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour XhlA PF10779.9 KFM83332.1 - 6.2 7.1 12.3 3.3 8.0 4.3 2.5 2 1 0 2 2 2 0 Haemolysin XhlA Nefa_Nip30_N PF10187.9 KFM83333.1 - 2.1e-29 101.9 14.4 2.1e-29 101.9 14.4 2.3 3 0 0 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 KFM83333.1 - 1.3 8.6 18.8 3.2 7.3 18.8 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF572) Spore_III_AB PF09548.10 KFM83333.1 - 2.7 8.1 9.5 1.6 8.8 6.8 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Arg_decarbox_C PF17944.1 KFM83333.1 - 4.7 7.9 6.4 21 5.7 1.0 2.9 2 1 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension zf-H2C2_2 PF13465.6 KFM83336.1 - 1.8e-44 148.2 46.1 2.5e-10 40.3 0.1 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83336.1 - 1.6e-25 88.0 54.8 1.1e-06 28.8 1.2 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83336.1 - 2.7e-20 71.3 50.4 0.00042 20.9 0.8 7.0 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM83336.1 - 5.9e-12 45.3 44.3 0.0014 18.6 1.8 7.2 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 KFM83336.1 - 2.5e-09 37.2 38.8 0.05 14.0 0.2 6.5 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM83336.1 - 3.6e-07 29.8 38.1 0.00066 19.4 0.0 7.8 7 1 0 7 7 7 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM83336.1 - 5.8e-06 26.4 36.1 0.23 11.8 0.2 6.7 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM83336.1 - 6.2e-05 23.2 6.5 7.4 6.9 2.6 4.6 1 1 2 4 4 4 0 BolA-like protein Baculo_IE-1 PF05290.11 KFM83336.1 - 0.0001 22.3 17.9 0.76 9.7 0.2 5.7 1 1 5 6 6 6 2 Baculovirus immediate-early protein (IE-0) Zf_RING PF16744.5 KFM83336.1 - 0.00017 21.6 24.2 1.6 8.9 0.5 6.0 1 1 5 6 6 6 2 KIAA1045 RING finger GAGA PF09237.11 KFM83336.1 - 0.005 16.6 9.8 0.29 11.0 0.2 4.3 1 1 3 5 5 5 1 GAGA factor FYVE PF01363.21 KFM83336.1 - 0.034 14.3 30.0 1.5 9.0 2.0 4.4 1 1 4 5 5 5 0 FYVE zinc finger zf-BED PF02892.15 KFM83336.1 - 0.056 13.5 38.8 0.058 13.4 1.4 6.3 1 1 5 6 6 6 0 BED zinc finger IL13 PF03487.13 KFM83336.1 - 0.06 13.1 0.5 0.11 12.3 0.5 1.4 1 0 0 1 1 1 0 Interleukin-13 zf-MYST PF17772.1 KFM83336.1 - 0.078 12.6 25.0 1.7 8.3 0.1 6.0 3 2 3 6 6 6 0 MYST family zinc finger domain zf-C2H2_8 PF15909.5 KFM83336.1 - 0.14 12.5 21.6 0.8 10.0 2.6 3.2 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-RING_11 PF17123.5 KFM83336.1 - 0.2 11.4 13.7 4.6 7.1 0.0 5.2 5 0 0 5 5 5 0 RING-like zinc finger zf-C2H2_2 PF12756.7 KFM83336.1 - 0.27 11.6 33.9 4 7.8 0.5 5.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM83336.1 - 0.34 11.7 23.4 0.7 10.7 0.4 3.2 1 1 2 3 3 3 0 zinc-ribbon family zf_UBZ PF18439.1 KFM83336.1 - 0.53 9.9 21.5 1.3 8.7 0.1 6.0 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFM83336.1 - 0.75 9.6 19.3 1.6 8.6 0.1 4.8 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFM83336.1 - 2.6 8.0 22.3 16 5.5 0.5 6.1 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Spt46 PF17734.1 KFM83336.1 - 3.2 7.5 13.6 2.7 7.7 0.2 3.4 1 1 3 4 4 4 0 Spermatogenesis-associated protein 46 zf-Sec23_Sec24 PF04810.15 KFM83336.1 - 4.3 7.5 24.9 3.7 7.7 0.3 6.2 4 2 3 7 7 7 0 Sec23/Sec24 zinc finger C1_4 PF07975.12 KFM83336.1 - 5.2 7.4 30.3 0.19 12.0 0.7 5.0 1 1 3 5 5 5 0 TFIIH C1-like domain HTH_Tnp_Tc3_2 PF01498.18 KFM83337.1 - 2.4e-16 59.7 2.2 4.6e-16 58.8 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM83337.1 - 9.9e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM83339.1 - 5.1e-16 58.7 3.5 6.2e-16 58.4 2.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 KFM83339.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KFM83339.1 - 3.1e-07 30.1 1.6 7.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KFM83339.1 - 0.0028 17.4 0.6 0.0081 15.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KFM83339.1 - 2.7 8.7 15.6 0.13 12.9 2.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_IS1595 PF12762.7 KFM83340.1 - 8.4e-20 71.3 0.3 1.8e-19 70.2 0.3 1.5 1 1 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.6 KFM83340.1 - 0.0023 17.7 0.0 0.0046 16.7 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF4203 PF13886.6 KFM83341.1 - 1.4e-25 90.2 34.6 1.8e-25 89.8 34.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DDE_3 PF13358.6 KFM83342.1 - 7.1e-17 61.5 0.1 3.2e-15 56.2 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFM83342.1 - 1.4e-10 41.2 1.0 2.7e-10 40.3 1.0 1.5 1 0 0 1 1 1 1 Transposase FLYWCH PF04500.16 KFM83344.1 - 7.8e-08 32.3 0.8 1.7e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 FLYWCH zinc finger domain GSHPx PF00255.19 KFM83346.1 - 3.8e-09 36.1 0.0 5.3e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFM83346.1 - 0.01 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family TBCC_N PF16752.5 KFM83347.1 - 0.0076 16.7 5.4 0.01 16.3 5.4 1.1 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain PepSY_TM_like_2 PF16357.5 KFM83347.1 - 0.16 11.9 1.8 0.18 11.8 1.8 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF16 PF01519.16 KFM83347.1 - 0.17 12.3 3.1 0.2 12.1 3.1 1.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 HTH_Tnp_Tc3_2 PF01498.18 KFM83349.1 - 7.6e-16 58.1 6.5 1.4e-15 57.3 6.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM83349.1 - 6.6e-14 51.9 0.0 1.2e-12 47.8 0.0 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFM83349.1 - 0.0007 20.2 1.5 0.0007 20.2 1.5 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KFM83349.1 - 0.0021 17.8 0.1 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFM83349.1 - 0.015 15.4 0.1 0.063 13.4 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFM83349.1 - 0.034 14.2 2.6 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DUF1899 PF08953.11 KFM83350.1 - 4.1e-29 100.2 0.2 8.2e-29 99.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 KFM83350.1 - 7.2e-14 52.0 7.6 4.6e-06 27.3 0.6 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM83350.1 - 7.8e-09 35.7 0.0 8.8e-05 22.7 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-H2C2_2 PF13465.6 KFM83351.1 - 1.7e-144 464.5 125.0 4.5e-08 33.2 0.4 19.1 19 0 0 19 19 19 18 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83351.1 - 1.8e-86 280.0 157.0 7.9e-07 29.2 1.7 19.1 19 0 0 19 19 19 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83351.1 - 1.9e-62 202.5 150.5 0.00016 22.2 1.1 19.2 19 0 0 19 19 19 18 C2H2-type zinc finger zf-met PF12874.7 KFM83351.1 - 3e-43 145.0 140.6 0.00084 19.6 1.3 18.4 18 0 0 18 18 18 18 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83351.1 - 3.1e-28 97.2 130.2 0.0077 16.2 0.8 18.4 18 0 0 18 18 18 15 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM83351.1 - 1.6e-23 82.4 105.4 0.084 13.2 0.4 18.6 16 2 2 18 18 18 15 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM83351.1 - 2.1e-18 65.7 88.8 0.014 15.1 1.2 19.1 19 0 0 19 19 19 8 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM83351.1 - 1.2e-11 44.4 56.4 0.087 12.8 0.5 11.7 4 4 10 14 14 14 10 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM83351.1 - 2.8e-07 30.6 11.9 0.24 11.6 0.0 6.8 2 2 2 7 7 7 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-C2HC_2 PF13913.6 KFM83351.1 - 2.1e-05 24.3 71.5 1.8 8.6 1.0 17.2 18 0 0 18 18 18 2 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFM83351.1 - 2.4e-05 24.0 104.2 0.086 12.6 0.6 18.5 19 0 0 19 19 19 6 zinc-finger C2H2-type DUF2256 PF10013.9 KFM83351.1 - 0.00022 21.3 69.1 11 6.2 0.1 17.3 18 0 0 18 18 18 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 KFM83351.1 - 0.00023 21.2 90.0 0.029 14.5 4.8 9.3 1 1 4 5 5 3 2 FYVE zinc finger zf-RRPl_C4 PF17026.5 KFM83351.1 - 0.00082 19.4 67.8 0.45 10.6 5.0 7.0 1 1 4 6 6 6 4 Putative ribonucleoprotein zinc-finger pf C4 type zf-Sec23_Sec24 PF04810.15 KFM83351.1 - 0.002 18.2 71.8 3.4 7.8 0.1 16.5 13 5 5 18 18 18 3 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM83351.1 - 0.033 14.3 71.1 6.9 6.9 0.2 15.7 17 0 0 17 17 16 0 DBF zinc finger GAGA PF09237.11 KFM83351.1 - 0.04 13.7 45.4 1.8 8.4 0.1 11.8 3 3 10 15 15 15 0 GAGA factor DZR PF12773.7 KFM83351.1 - 0.12 12.5 62.2 1.1 9.4 0.7 9.5 1 1 1 2 2 1 0 Double zinc ribbon BHD_1 PF10403.9 KFM83351.1 - 0.19 11.6 2.0 1.7e+02 2.1 0.0 5.1 5 1 0 5 5 5 0 Rad4 beta-hairpin domain 1 eRF1_2 PF03464.15 KFM83351.1 - 0.26 11.6 7.0 17 5.7 0.0 5.3 4 1 1 6 6 6 0 eRF1 domain 2 zf-C2H2_9 PF16293.5 KFM83351.1 - 1.1 9.2 75.7 5.4 7.0 0.0 17.2 2 2 17 19 19 19 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFM83351.1 - 1.9 9.3 68.9 1.6 9.5 1.2 9.3 2 2 6 10 10 10 0 zinc-ribbon family DUF952 PF06108.12 KFM83351.1 - 4.9 7.2 9.2 21 5.2 0.0 6.0 6 2 2 8 8 8 0 Protein of unknown function (DUF952) Lamprin PF06403.11 KFM83353.1 - 0.86 9.6 5.2 0.99 9.4 5.2 1.3 1 1 0 1 1 1 0 Lamprin zf-ribbon_3 PF13248.6 KFM83354.1 - 0.0003 20.1 2.3 0.00057 19.2 2.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KFM83354.1 - 0.007 16.4 0.9 0.011 15.7 0.9 1.5 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFM83354.1 - 0.012 16.4 2.2 0.018 15.8 2.2 1.3 1 0 0 1 1 1 0 zinc-ribbon family Tom6 PF17112.5 KFM83354.1 - 0.041 13.4 0.3 0.084 12.4 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal DUF3223 PF11523.8 KFM83354.1 - 0.047 14.5 0.1 0.11 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3223) TF_Zn_Ribbon PF08271.12 KFM83354.1 - 0.4 10.2 6.0 1.3 8.6 6.0 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding Myb_DNA-bind_5 PF13873.6 KFM83356.1 - 4.5e-07 29.8 0.0 5.4e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-H2C2_2 PF13465.6 KFM83357.1 - 9.1e-89 288.3 83.5 1e-07 32.1 1.8 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83357.1 - 7.6e-55 180.4 115.2 1.3e-05 25.3 2.6 13.1 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83357.1 - 7.7e-41 135.2 108.0 0.0014 19.3 1.3 13.0 13 0 0 13 13 13 12 C2H2-type zinc finger zf-met PF12874.7 KFM83357.1 - 5e-23 80.7 98.7 0.016 15.5 0.9 13.4 12 1 0 13 13 13 12 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83357.1 - 1.9e-14 53.5 74.5 0.048 14.0 0.5 12.6 12 0 0 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83357.1 - 1.2e-12 47.4 84.9 0.1 12.6 1.6 13.4 13 1 0 13 13 12 10 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM83357.1 - 9.9e-12 44.7 48.2 0.13 12.3 0.2 11.9 9 2 3 12 12 12 5 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM83357.1 - 6.9e-09 35.4 48.4 1.3 9.0 0.1 12.5 12 0 0 12 12 12 2 zinc-finger of a C2HC-type GAGA PF09237.11 KFM83357.1 - 6.2e-06 25.9 34.1 0.18 11.6 2.6 8.7 1 1 10 11 11 11 4 GAGA factor ADK_lid PF05191.14 KFM83357.1 - 4.8e-05 23.2 41.0 0.099 12.6 0.4 7.4 4 2 4 8 8 8 4 Adenylate kinase, active site lid Tox-HNH-HHH PF15637.6 KFM83357.1 - 0.0003 20.9 6.2 6.2 7.0 0.1 5.1 1 1 6 7 7 7 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-DBF PF07535.12 KFM83357.1 - 0.00073 19.6 56.6 7 6.8 0.2 12.1 11 1 1 12 12 12 0 DBF zinc finger Phage-A118_gp45 PF10653.9 KFM83357.1 - 0.00092 19.2 0.2 16 5.6 0.0 5.1 3 2 2 5 5 5 0 Protein gp45 of Bacteriophage A118 BolA PF01722.18 KFM83357.1 - 0.004 17.4 23.5 1.1 9.6 2.2 6.8 1 1 5 6 6 6 1 BolA-like protein K_oxygenase PF13434.6 KFM83357.1 - 0.047 12.8 1.1 6.3 5.8 0.1 3.6 1 1 2 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF3396 PF11876.8 KFM83357.1 - 0.051 13.0 0.0 12 5.3 0.0 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF3396) HNH_5 PF14279.6 KFM83357.1 - 0.11 12.4 57.1 0.18 11.7 2.7 10.0 8 2 1 9 9 9 0 HNH endonuclease TAFII28 PF04719.14 KFM83357.1 - 0.13 12.4 0.1 14 5.8 0.0 3.8 2 1 2 4 4 4 0 hTAFII28-like protein conserved region BHD_1 PF10403.9 KFM83357.1 - 0.14 12.0 5.6 34 4.4 0.0 5.1 4 1 1 5 5 5 0 Rad4 beta-hairpin domain 1 PqqA PF08042.11 KFM83357.1 - 0.16 12.0 3.0 4.8e+02 1.0 0.0 6.3 8 0 0 8 8 8 0 PqqA family Zn-ribbon_8 PF09723.10 KFM83357.1 - 1 9.5 43.5 0.59 10.3 1.1 7.4 3 2 4 7 7 7 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFM83357.1 - 1.2 9.9 48.1 1.5 9.6 1.1 6.4 2 2 2 5 5 5 0 zinc-ribbon family zf-RRPl_C4 PF17026.5 KFM83357.1 - 3.4 7.8 51.5 0.95 9.6 4.7 5.4 1 1 4 5 5 5 0 Putative ribonucleoprotein zinc-finger pf C4 type DNA_primase_S PF01896.19 KFM83357.1 - 4 7.4 14.2 0.31 11.1 2.0 3.5 2 2 0 2 2 2 0 DNA primase small subunit zf_UBZ PF18439.1 KFM83357.1 - 5.6 6.7 59.0 3.3 7.4 0.2 11.8 12 0 0 12 12 12 0 Ubiquitin-Binding Zinc Finger Zf_RING PF16744.5 KFM83357.1 - 8 6.7 61.5 0.25 11.5 0.6 11.0 1 1 9 10 10 8 0 KIAA1045 RING finger Glyco_hydro_20 PF00728.22 KFM83360.1 - 1.3e-15 57.7 0.9 3.3e-15 56.3 0.3 1.9 2 1 1 3 3 3 1 Glycosyl hydrolase family 20, catalytic domain DUF4838 PF16126.5 KFM83360.1 - 0.00013 21.4 0.1 0.00024 20.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) Kazal_2 PF07648.15 KFM83360.1 - 0.18 12.0 0.1 0.39 10.9 0.1 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain MA3 PF02847.17 KFM83364.1 - 0.0074 16.3 0.1 0.0074 16.3 0.1 1.0 1 0 0 1 1 1 1 MA3 domain BAR_3 PF16746.5 KFM83366.1 - 2e-56 191.4 10.9 2.8e-56 190.9 10.9 1.2 1 0 0 1 1 1 1 BAR domain of APPL family DUF4859 PF16151.5 KFM83366.1 - 0.055 13.3 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) CBX7_C PF17218.3 KFM83366.1 - 0.059 13.1 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 CBX family C-terminal motif LUC7 PF03194.15 KFM83366.1 - 0.063 12.9 8.3 1.6 8.4 0.5 2.2 2 0 0 2 2 2 0 LUC7 N_terminus RNase_J_C PF17770.1 KFM83366.1 - 0.87 10.7 3.1 15 6.7 0.2 3.1 3 1 0 3 3 3 0 Ribonuclease J C-terminal domain DUF87 PF01935.17 KFM83366.1 - 1 9.4 4.0 5.1 7.1 4.1 1.9 1 1 0 1 1 1 0 Helicase HerA, central domain Lebercilin PF15619.6 KFM83366.1 - 1.6 8.4 12.5 2.1 8.0 5.2 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PRESAN PF09687.10 KFM83366.1 - 2.2 8.9 15.3 3 8.4 4.9 2.6 1 1 1 2 2 2 0 Plasmodium RESA N-terminal HTH_Tnp_Tc3_2 PF01498.18 KFM83368.1 - 2e-16 60.0 2.2 3.6e-16 59.2 2.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KFM83368.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 KFM83369.1 - 4.8e-104 336.6 115.8 3.6e-08 33.5 0.1 16.1 16 0 0 16 16 16 16 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83369.1 - 4.7e-66 215.7 135.2 1.6e-07 31.4 1.0 15.1 15 0 0 15 15 15 14 Zinc finger, C2H2 type zf-met PF12874.7 KFM83369.1 - 8.6e-42 140.4 114.9 0.00075 19.8 1.4 14.5 14 0 0 14 14 14 14 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM83369.1 - 1e-41 138.0 130.0 0.00075 20.1 1.0 15.0 15 0 0 15 15 15 14 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM83369.1 - 1.9e-18 66.2 77.9 0.13 12.5 0.2 14.2 14 0 0 14 14 14 11 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83369.1 - 3.7e-17 61.9 110.8 0.016 15.2 0.7 14.9 15 1 0 15 15 15 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM83369.1 - 6.5e-14 51.4 77.3 0.021 14.6 0.4 14.6 15 0 0 15 15 15 6 C2H2-type zinc-finger domain zf-RRPl_C4 PF17026.5 KFM83369.1 - 1.7e-07 31.3 61.9 0.028 14.5 4.9 6.4 1 1 6 7 7 7 7 Putative ribonucleoprotein zinc-finger pf C4 type zf-DBF PF07535.12 KFM83369.1 - 1.4e-06 28.3 55.8 9.7 6.4 0.1 13.2 14 0 0 14 14 13 0 DBF zinc finger GAGA PF09237.11 KFM83369.1 - 3.6e-06 26.7 34.5 0.36 10.7 0.1 10.1 3 2 9 12 12 12 4 GAGA factor zf-Sec23_Sec24 PF04810.15 KFM83369.1 - 5.2e-06 26.4 50.3 4.5 7.4 0.8 13.9 8 6 7 15 15 15 2 Sec23/Sec24 zinc finger zf-MYST PF17772.1 KFM83369.1 - 1.7e-05 24.4 79.1 0.023 14.3 0.4 14.3 7 5 8 15 15 15 5 MYST family zinc finger domain zf-C2H2_9 PF16293.5 KFM83369.1 - 0.0021 17.9 73.1 4.5 7.2 0.4 14.2 4 4 11 15 15 15 4 C2H2 type zinc-finger (1 copy) Tox-HNH-HHH PF15637.6 KFM83369.1 - 0.0024 18.0 4.3 21 5.3 0.0 5.3 3 3 3 6 6 6 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif C1_1 PF00130.22 KFM83369.1 - 0.0026 17.6 81.0 0.57 10.1 2.0 11.9 4 4 5 11 11 11 2 Phorbol esters/diacylglycerol binding domain (C1 domain) K_oxygenase PF13434.6 KFM83369.1 - 0.0065 15.7 6.7 5.6 6.0 0.2 5.3 2 1 4 6 6 6 1 L-lysine 6-monooxygenase (NADPH-requiring) zinc_ribbon_15 PF17032.5 KFM83369.1 - 0.0066 17.2 59.6 1.1 10.0 0.6 7.7 2 2 6 8 8 8 4 zinc-ribbon family BolA PF01722.18 KFM83369.1 - 0.0075 16.5 33.3 1.3 9.4 0.4 8.9 1 1 7 9 9 9 2 BolA-like protein DUF2256 PF10013.9 KFM83369.1 - 0.022 14.9 62.7 3.3 7.9 0.1 13.7 14 0 0 14 14 14 0 Uncharacterized protein conserved in bacteria (DUF2256) Complex1_49kDa PF00346.19 KFM83369.1 - 0.083 12.0 7.4 11 5.0 0.1 4.1 2 1 1 4 4 4 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Zf_RING PF16744.5 KFM83369.1 - 1.2 9.3 76.7 11 6.2 0.3 13.3 1 1 12 13 13 13 0 KIAA1045 RING finger zf-FPG_IleRS PF06827.14 KFM83369.1 - 9 6.3 50.1 17 5.4 0.3 12.8 13 1 0 13 13 13 0 Zinc finger found in FPG and IleRS zf-H2C2_2 PF13465.6 KFM83371.1 - 3.5e-54 178.9 71.6 1.3e-08 34.9 0.7 9.9 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83371.1 - 3.4e-41 137.4 80.7 2.1e-06 27.9 1.4 10.2 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83371.1 - 1.4e-29 100.2 74.8 0.00044 20.9 0.2 10.2 10 0 0 10 10 10 8 C2H2-type zinc finger zf-met PF12874.7 KFM83371.1 - 2.5e-13 49.9 74.7 0.0054 17.1 0.3 10.3 11 0 0 11 11 10 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83371.1 - 1.9e-07 31.2 53.6 0.31 11.4 2.3 9.9 10 0 0 10 10 9 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83371.1 - 2.9e-07 30.3 74.4 0.023 14.7 0.9 10.8 11 1 0 11 11 10 6 C2H2-type zinc finger Tox-HNH-HHH PF15637.6 KFM83371.1 - 2.2e-06 27.7 6.1 0.86 9.8 0.2 4.2 1 1 3 4 4 4 3 HNH/Endo VII superfamily nuclease toxin with a HHH motif GAGA PF09237.11 KFM83371.1 - 2.1e-05 24.2 11.1 0.8 9.6 0.0 6.0 2 1 5 7 7 7 2 GAGA factor zf-C2H2_9 PF16293.5 KFM83371.1 - 7.5e-05 22.5 36.3 1.4 8.9 0.4 8.5 4 1 5 9 9 9 3 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFM83371.1 - 9.4e-05 22.1 59.2 0.11 12.3 0.4 9.0 9 0 0 9 9 9 5 zinc-finger C2H2-type zf-Dof PF02701.15 KFM83371.1 - 0.00045 20.3 22.0 0.6 10.3 0.8 6.7 2 1 5 7 7 7 1 Dof domain, zinc finger zf-RRPl_C4 PF17026.5 KFM83371.1 - 0.00052 20.1 35.2 0.12 12.4 6.3 4.1 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type Complex1_49kDa PF00346.19 KFM83371.1 - 0.0016 17.6 1.4 0.79 8.8 0.1 2.8 1 1 2 3 3 3 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit BolA PF01722.18 KFM83371.1 - 0.0027 17.9 15.9 1.7 9.0 2.6 5.5 1 1 3 4 4 4 2 BolA-like protein C1_1 PF00130.22 KFM83371.1 - 0.0068 16.3 45.9 3.6 7.6 0.2 7.7 6 1 1 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Sec23_Sec24 PF04810.15 KFM83371.1 - 0.067 13.2 22.9 7.5 6.7 0.2 7.3 6 1 1 7 7 7 0 Sec23/Sec24 zinc finger ATP-grasp_4 PF13535.6 KFM83371.1 - 0.073 12.7 0.1 10 5.7 0.0 3.6 1 1 3 5 5 5 0 ATP-grasp domain FYVE PF01363.21 KFM83371.1 - 0.11 12.6 41.8 0.077 13.1 4.7 4.7 2 2 2 5 5 5 0 FYVE zinc finger TRAF6_Z2 PF18048.1 KFM83371.1 - 0.31 11.2 47.4 1.6 8.9 0.9 9.2 9 1 1 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2HC_2 PF13913.6 KFM83371.1 - 0.43 10.5 29.0 2.5 8.1 0.8 7.9 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFM83371.1 - 0.62 9.7 38.1 10 5.8 0.3 8.3 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM83371.1 - 4.7 6.9 28.8 3.1 7.5 0.3 7.4 5 3 2 7 7 7 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFM83371.1 - 5.8 7.7 36.8 1.4 9.7 5.2 5.1 2 2 2 5 5 5 0 zinc-ribbon family zf-C2H2_2 PF12756.7 KFM83371.1 - 7.5 7.0 65.4 6.4 7.2 0.1 8.4 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFM83374.1 - 1.6e-144 464.5 117.9 3.2e-09 36.8 1.5 18.1 18 0 0 18 18 18 18 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83374.1 - 2.8e-79 257.4 159.8 4e-05 23.8 1.9 18.7 19 0 0 19 19 19 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83374.1 - 1.1e-56 184.5 149.6 0.0026 18.4 0.6 18.4 19 0 0 19 19 18 17 C2H2-type zinc finger zf-met PF12874.7 KFM83374.1 - 1.5e-45 152.3 135.4 0.0043 17.4 1.0 18.4 18 0 0 18 18 18 17 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83374.1 - 9.8e-27 92.6 92.3 0.14 12.5 0.7 18.7 18 1 1 19 19 19 13 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83374.1 - 8.2e-25 86.3 125.6 0.002 18.1 0.2 19.3 19 1 0 19 19 18 14 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM83374.1 - 2.5e-17 62.3 89.2 0.032 14.0 0.3 17.9 18 0 0 18 18 18 8 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFM83374.1 - 3.1e-15 55.9 50.9 0.032 14.2 1.3 10.8 7 3 2 10 10 9 7 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM83374.1 - 1.4e-11 44.3 58.0 0.69 10.1 0.1 16.6 17 0 0 17 17 17 3 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.18 KFM83374.1 - 1.5e-08 34.8 28.4 0.24 11.7 0.2 8.6 3 3 4 8 8 8 3 BolA-like protein Tox-HNH-HHH PF15637.6 KFM83374.1 - 3.5e-07 30.3 11.9 2.1 8.6 0.0 7.7 1 1 8 10 10 10 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif FYVE PF01363.21 KFM83374.1 - 1.9e-06 27.9 92.0 0.012 15.7 9.7 8.6 1 1 7 8 8 8 5 FYVE zinc finger zf-C2HC_2 PF13913.6 KFM83374.1 - 9.7e-06 25.4 73.4 1.1 9.3 0.1 17.1 17 0 0 17 17 17 2 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFM83374.1 - 0.00034 20.6 64.9 14 5.9 0.1 15.9 12 3 5 17 17 17 0 Sec23/Sec24 zinc finger zf-CHCC PF10276.9 KFM83374.1 - 0.00034 20.6 27.4 91 3.2 0.0 14.1 17 0 0 17 17 17 0 Zinc-finger domain zf-DBF PF07535.12 KFM83374.1 - 0.0006 19.9 71.4 14 5.9 0.3 15.8 17 0 0 17 17 17 0 DBF zinc finger DUF3396 PF11876.8 KFM83374.1 - 0.00098 18.6 0.0 0.73 9.3 0.0 4.6 2 2 4 6 6 6 1 Protein of unknown function (DUF3396) GAGA PF09237.11 KFM83374.1 - 0.0014 18.4 0.8 0.0014 18.4 0.8 11.3 3 2 10 13 13 13 1 GAGA factor Complex1_49kDa PF00346.19 KFM83374.1 - 0.0072 15.5 1.0 4.1 6.4 0.0 4.2 2 1 3 6 6 6 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-MYST PF17772.1 KFM83374.1 - 0.0093 15.6 69.1 1.5 8.5 0.7 15.3 11 5 5 16 16 16 1 MYST family zinc finger domain NBD94 PF16830.5 KFM83374.1 - 0.071 13.5 0.0 16 5.9 0.0 3.3 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH DUF952 PF06108.12 KFM83374.1 - 0.14 12.1 4.2 18 5.4 0.0 5.2 4 2 2 7 7 7 0 Protein of unknown function (DUF952) PqqA PF08042.11 KFM83374.1 - 0.42 10.7 16.5 6.7e+02 0.6 0.0 10.7 14 0 0 14 14 14 0 PqqA family C5HCH PF17982.1 KFM83374.1 - 1.5 9.0 77.6 20 5.5 2.1 15.9 14 2 3 17 17 17 0 NSD Cys-His rich domain zf-RRPl_C4 PF17026.5 KFM83374.1 - 2.7 8.1 65.7 2.2 8.4 4.0 7.1 1 1 6 7 7 7 0 Putative ribonucleoprotein zinc-finger pf C4 type Exo_endo_phos_2 PF14529.6 KFM83375.1 - 0.0054 16.6 0.1 0.0089 15.9 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Acetyltransf_9 PF13527.7 KFM83376.1 - 0.099 12.7 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PRE_C2HC PF07530.11 KFM83379.1 - 0.004 17.2 0.3 0.007 16.5 0.3 1.4 1 0 0 1 1 1 1 Associated with zinc fingers zf-CCHC_4 PF14392.6 KFM83379.1 - 0.4 10.4 4.6 1 9.2 4.6 1.7 1 0 0 1 1 1 0 Zinc knuckle RUN PF02759.19 KFM83381.1 - 2.1e-11 43.9 0.3 4.9e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 RUN domain rve PF00665.26 KFM83382.1 - 2.8e-22 79.2 0.0 2.2e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KFM83382.1 - 5.2e-10 39.3 2.7 1e-09 38.4 2.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KFM83382.1 - 0.0077 16.0 0.0 0.042 13.6 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFM83382.1 - 0.012 15.8 0.4 0.026 14.8 0.4 1.6 1 0 0 1 1 1 0 H2C2 zinc finger MLVIN_C PF18697.1 KFM83382.1 - 0.031 14.4 0.1 0.066 13.3 0.1 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_3 PF13358.6 KFM83383.1 - 0.015 15.0 0.1 0.03 14.1 0.0 1.5 2 0 0 2 2 2 0 DDE superfamily endonuclease zf-C2H2 PF00096.26 KFM83385.1 - 0.003 17.9 0.6 0.003 17.9 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83385.1 - 0.056 14.3 0.4 0.056 14.3 0.4 2.3 2 1 0 2 2 2 0 C2H2-type zinc finger GATA PF00320.27 KFM83385.1 - 0.082 12.5 0.6 0.24 11.0 0.6 1.9 1 1 0 1 1 1 0 GATA zinc finger zf-CCCH_7 PF18586.1 KFM83385.1 - 0.11 12.8 1.5 0.13 12.6 1.5 1.2 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 zf-H2C2_2 PF13465.6 KFM83386.1 - 6.1e-42 140.2 25.7 2.8e-09 37.0 0.5 5.0 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83386.1 - 2.9e-25 87.3 29.6 2.6e-07 30.7 0.4 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83386.1 - 5.5e-21 73.4 28.1 1.6e-05 25.4 0.4 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KFM83386.1 - 8.2e-17 61.0 28.5 7.2e-06 26.2 0.7 5.3 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83386.1 - 1e-12 48.0 20.2 0.0012 19.0 0.1 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83386.1 - 7.8e-09 35.3 28.0 0.064 13.3 0.3 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM83386.1 - 3.6e-07 29.8 24.9 0.0031 17.2 0.3 4.9 5 1 0 5 5 4 3 C2H2-type zinc-finger domain BolA PF01722.18 KFM83386.1 - 2.2e-06 27.9 1.0 0.029 14.6 0.3 3.4 1 1 2 3 3 3 3 BolA-like protein zf_UBZ PF18439.1 KFM83386.1 - 2.8e-06 26.8 15.6 0.83 9.3 0.0 5.1 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KFM83386.1 - 7.4e-06 25.5 16.9 0.09 12.4 0.2 4.9 2 2 3 5 5 5 3 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 KFM83386.1 - 3.3e-05 23.9 12.5 0.98 9.5 0.1 5.1 3 2 2 5 5 5 1 Sec23/Sec24 zinc finger C1_1 PF00130.22 KFM83386.1 - 0.00036 20.4 16.7 0.55 10.2 4.0 4.5 3 2 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-DBF PF07535.12 KFM83386.1 - 0.00055 20.0 20.3 3.4 7.8 0.2 5.3 5 0 0 5 5 5 1 DBF zinc finger GAGA PF09237.11 KFM83386.1 - 0.0018 18.1 8.1 0.0059 16.4 0.7 3.6 2 2 3 5 5 5 1 GAGA factor DUF2256 PF10013.9 KFM83386.1 - 0.0039 17.3 15.0 5.6 7.2 0.5 5.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 KFM83386.1 - 0.0064 16.3 11.2 3.1 7.7 0.1 4.3 1 1 4 5 5 5 1 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFM83386.1 - 0.0067 16.2 17.6 0.039 13.7 0.4 4.6 5 0 0 5 5 5 2 zinc-finger C2H2-type Zf_RING PF16744.5 KFM83386.1 - 0.0068 16.5 18.1 3.3 7.9 0.2 4.9 1 1 3 4 4 4 1 KIAA1045 RING finger zinc-ribbons_6 PF07191.12 KFM83386.1 - 0.011 15.6 17.0 5.1 7.1 0.3 4.5 1 1 3 4 4 4 0 zinc-ribbons zf-C2H2_2 PF12756.7 KFM83386.1 - 0.013 15.8 23.7 1.3 9.4 0.6 4.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM83386.1 - 0.015 16.0 16.4 0.62 10.9 2.2 3.0 1 1 1 3 3 3 0 zinc-ribbon family zf-BED PF02892.15 KFM83386.1 - 0.033 14.2 26.1 0.69 10.0 1.9 5.0 1 1 4 5 5 5 0 BED zinc finger zf-C2HC_2 PF13913.6 KFM83386.1 - 0.046 13.6 16.8 7.1 6.7 1.0 4.9 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Baculo_IE-1 PF05290.11 KFM83386.1 - 0.055 13.4 16.1 6.9 6.6 6.8 4.7 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) NusB PF01029.18 KFM83386.1 - 0.056 13.7 0.1 4.3 7.6 0.0 2.3 1 1 2 3 3 3 0 NusB family zf-RRPl_C4 PF17026.5 KFM83386.1 - 0.12 12.4 16.3 1.1 9.4 2.3 2.4 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 KFM83386.1 - 0.13 12.4 18.2 1 9.6 1.9 4.1 1 1 3 4 4 4 0 Zinc ribbon domain Prok-RING_2 PF14445.6 KFM83386.1 - 0.14 12.4 7.1 81 3.5 0.0 4.7 4 1 0 4 4 4 0 Prokaryotic RING finger family 2 C1_4 PF07975.12 KFM83386.1 - 0.15 12.3 19.6 4.5 7.6 2.9 3.8 1 1 4 5 5 5 0 TFIIH C1-like domain zf-FPG_IleRS PF06827.14 KFM83386.1 - 0.19 11.7 16.0 5.5 6.9 0.2 4.9 4 1 1 5 5 5 0 Zinc finger found in FPG and IleRS Zn_ribbon_SprT PF17283.2 KFM83386.1 - 0.2 11.6 11.6 12 5.9 0.1 4.1 4 0 0 4 4 4 0 SprT-like zinc ribbon domain DUF5330 PF17264.2 KFM83386.1 - 0.23 11.5 9.8 22 5.1 0.0 4.3 5 0 0 5 5 4 0 Family of unknown function (DUF5330) zf-trcl PF13451.6 KFM83386.1 - 0.35 10.8 15.3 15 5.6 0.1 5.0 5 0 0 5 5 5 0 Probable zinc-ribbon domain TRAF6_Z2 PF18048.1 KFM83386.1 - 1 9.5 16.8 5.2 7.2 0.2 4.0 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 DUF3268 PF11672.8 KFM83386.1 - 3 8.2 10.0 11 6.4 0.4 3.0 2 1 1 3 3 3 0 zinc-finger-containing domain C5HCH PF17982.1 KFM83386.1 - 3.7 7.8 18.7 10 6.3 0.2 4.8 2 2 3 5 5 5 0 NSD Cys-His rich domain zf-CCHC_2 PF13696.6 KFM83386.1 - 4.3 7.2 22.5 3.4 7.6 0.4 4.7 5 0 0 5 5 5 0 Zinc knuckle FYVE PF01363.21 KFM83386.1 - 6.2 7.0 21.6 36 4.6 3.4 3.8 1 1 1 2 2 2 0 FYVE zinc finger zf-H2C2_2 PF13465.6 KFM83387.1 - 1.4e-12 47.4 7.3 5.2e-06 26.6 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83387.1 - 9.7e-08 32.1 5.8 0.00011 22.5 0.6 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 KFM83387.1 - 1.3e-06 28.6 6.5 0.0015 18.8 0.7 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM83387.1 - 1.6e-06 28.5 7.0 0.00035 21.2 0.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFM83387.1 - 1.8e-05 24.5 0.9 0.01 15.7 0.0 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFM83387.1 - 0.00025 20.9 8.0 0.11 12.5 0.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM83387.1 - 0.00031 20.7 2.0 0.047 13.7 0.1 2.0 1 1 1 2 2 2 2 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KFM83387.1 - 0.00045 20.4 7.5 0.06 13.7 0.8 2.5 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 KFM83387.1 - 0.0043 17.1 2.9 1 9.5 0.2 2.3 2 0 0 2 2 2 2 DBF zinc finger DUF2256 PF10013.9 KFM83387.1 - 0.0081 16.3 0.9 2.9 8.1 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) Zf_RING PF16744.5 KFM83387.1 - 0.0081 16.3 2.6 0.81 9.8 0.3 2.0 1 1 1 2 2 2 2 KIAA1045 RING finger Zn-ribbon_8 PF09723.10 KFM83387.1 - 0.013 15.6 1.3 0.04 14.0 1.3 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zf-trcl PF13451.6 KFM83387.1 - 0.016 15.1 1.5 3.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf_UBZ PF18439.1 KFM83387.1 - 0.018 14.6 3.2 1.8 8.2 0.4 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-SNAP50_C PF12251.8 KFM83387.1 - 0.022 14.5 2.3 0.021 14.5 2.3 1.0 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zinc-ribbons_6 PF07191.12 KFM83387.1 - 0.022 14.7 2.6 0.41 10.7 2.6 2.0 1 1 0 1 1 1 0 zinc-ribbons U71 PF17474.2 KFM83387.1 - 0.027 14.4 2.5 0.78 9.7 0.1 2.1 2 0 0 2 2 2 0 Tegument protein UL11 homolog zf-Di19 PF05605.12 KFM83387.1 - 0.029 14.6 3.8 0.031 14.6 3.2 1.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFM83387.1 - 0.036 13.8 1.2 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type Vps39_2 PF10367.9 KFM83387.1 - 0.07 13.6 5.6 1.3 9.5 0.7 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 C1_4 PF07975.12 KFM83387.1 - 0.079 13.2 4.5 1.2 9.5 0.4 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain C1_1 PF00130.22 KFM83387.1 - 0.091 12.7 3.5 4.8 7.1 0.2 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KFM83387.1 - 0.14 12.2 2.4 0.48 10.5 2.4 1.8 1 1 0 1 1 1 0 Adenylate kinase, active site lid Zn-C2H2_12 PF18112.1 KFM83387.1 - 0.17 12.4 5.5 2.2 8.9 0.5 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-AN1 PF01428.16 KFM83387.1 - 0.2 11.9 6.1 2.8 8.2 0.9 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger Cas_CXXC_CXXC PF09706.10 KFM83387.1 - 0.26 11.5 4.4 4.2 7.7 0.4 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Evr1_Alr PF04777.13 KFM83387.1 - 0.34 11.4 2.8 3.6 8.1 0.3 2.0 1 1 1 2 2 2 0 Erv1 / Alr family zf-C2HE PF16278.5 KFM83387.1 - 0.43 11.1 5.3 4 8.0 1.3 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CCHC_2 PF13696.6 KFM83387.1 - 0.43 10.4 5.6 5 7.0 0.5 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF2225 PF09986.9 KFM83387.1 - 0.53 10.0 6.3 0.17 11.6 0.8 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-met2 PF12907.7 KFM83387.1 - 3.9 7.7 8.6 9.3 6.5 2.7 2.5 2 1 0 2 2 2 0 Zinc-binding zf-H2C2_2 PF13465.6 KFM83389.1 - 6.8e-71 231.8 72.2 7.2e-09 35.7 0.4 12.8 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83389.1 - 2.5e-48 159.9 81.4 5.9e-06 26.5 0.8 12.2 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83389.1 - 1.4e-40 134.4 79.6 0.00016 22.3 0.8 12.2 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFM83389.1 - 1.2e-21 76.2 60.0 0.0001 22.2 0.3 12.9 12 1 0 12 12 12 9 C2H2-type zinc finger zf-met PF12874.7 KFM83389.1 - 1.7e-20 72.7 77.5 0.0042 17.4 0.7 12.4 12 0 0 12 12 12 9 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.15 KFM83389.1 - 1e-12 47.8 27.9 0.036 14.1 0.1 9.9 5 2 5 10 10 10 5 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.6 KFM83389.1 - 4e-10 39.3 54.4 0.073 12.8 0.4 11.4 12 0 0 12 12 11 6 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFM83389.1 - 7.3e-10 38.9 52.2 0.023 15.0 0.5 12.3 11 1 1 12 12 12 4 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFM83389.1 - 0.0041 17.4 14.5 4.2 7.7 0.1 6.5 1 1 3 5 5 5 1 BolA-like protein DZR PF12773.7 KFM83389.1 - 0.025 14.6 30.7 0.16 12.0 1.7 5.9 3 1 1 4 4 3 0 Double zinc ribbon zf-C2HC_2 PF13913.6 KFM83389.1 - 0.15 12.0 43.3 0.69 9.9 0.1 9.4 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFM83389.1 - 0.22 11.3 53.7 1.7 8.5 0.2 9.8 10 1 1 11 11 11 0 zinc-finger C2H2-type ADK_lid PF05191.14 KFM83389.1 - 0.89 9.6 39.1 0.66 10.0 1.0 7.2 4 1 2 6 6 6 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 KFM83389.1 - 1.1 9.4 33.9 0.17 12.0 0.5 7.4 5 2 3 8 8 8 0 Zinc ribbon domain DUF5330 PF17264.2 KFM83389.1 - 2 8.5 19.1 58 3.8 0.0 7.5 9 0 0 9 9 9 0 Family of unknown function (DUF5330) Scramblase PF03803.15 KFM83389.1 - 3.4 6.9 12.4 13 5.0 0.3 3.6 1 1 4 5 5 5 0 Scramblase zf-CHCC PF10276.9 KFM83389.1 - 4 7.6 23.3 25 5.1 0.3 7.9 9 0 0 9 9 9 0 Zinc-finger domain DUF2256 PF10013.9 KFM83389.1 - 5.6 7.2 35.0 10 6.3 0.0 10.1 12 0 0 12 12 10 0 Uncharacterized protein conserved in bacteria (DUF2256) PqqA PF08042.11 KFM83389.1 - 5.8 7.1 7.2 2.1e+02 2.1 0.1 5.3 6 0 0 6 6 6 0 PqqA family zf-H2C2_2 PF13465.6 KFM83390.1 - 4.2e-67 219.8 79.5 4.2e-09 36.4 0.6 11.1 11 0 0 11 11 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83390.1 - 3e-44 147.0 90.7 3.9e-06 27.0 1.3 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83390.1 - 1.4e-35 118.9 85.7 0.00021 21.9 1.1 10.2 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM83390.1 - 1.7e-21 75.9 86.9 0.0055 17.1 2.3 10.5 10 0 0 10 10 10 10 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFM83390.1 - 1.8e-19 69.2 54.7 0.0017 18.0 0.3 10.6 10 0 0 10 10 10 8 C2H2-type zinc-finger domain BolA PF01722.18 KFM83390.1 - 3.8e-14 52.7 16.5 0.033 14.5 1.0 7.7 1 1 5 7 7 7 3 BolA-like protein zf-C2HC_2 PF13913.6 KFM83390.1 - 6.2e-10 38.7 37.4 2.4 8.1 0.1 10.6 10 0 0 10 10 10 3 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFM83390.1 - 2.9e-09 36.7 74.9 0.49 10.5 0.4 11.7 11 0 0 11 11 11 7 C2H2-type zinc finger IGPD PF00475.18 KFM83390.1 - 3.1e-06 27.5 9.5 0.85 9.9 0.1 5.1 5 0 0 5 5 5 1 Imidazoleglycerol-phosphate dehydratase GAGA PF09237.11 KFM83390.1 - 2.3e-05 24.1 28.7 0.31 10.9 0.0 8.3 2 2 7 9 9 9 2 GAGA factor zf-C2H2_jaz PF12171.8 KFM83390.1 - 3.4e-05 24.0 64.1 0.87 10.0 1.0 10.3 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding Tox-HNH-HHH PF15637.6 KFM83390.1 - 0.00011 22.3 2.2 9.3 6.5 0.0 4.4 1 1 3 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif zf-Sec23_Sec24 PF04810.15 KFM83390.1 - 0.00018 21.5 41.2 0.15 12.1 0.9 10.1 8 2 2 10 10 10 1 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFM83390.1 - 0.00054 20.0 53.4 8 6.7 0.1 10.3 10 0 0 10 10 10 0 DBF zinc finger PqqA PF08042.11 KFM83390.1 - 0.0047 16.9 3.8 3.7e+02 1.4 0.0 6.6 7 0 0 7 7 7 0 PqqA family SPARC_Ca_bdg PF10591.9 KFM83390.1 - 0.0058 16.9 15.5 3.8 7.9 0.7 5.7 3 2 2 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region PUF PF00806.19 KFM83390.1 - 0.0067 16.1 1.0 52 3.8 0.0 5.1 6 0 0 6 6 6 0 Pumilio-family RNA binding repeat DUF4990 PF16380.5 KFM83390.1 - 0.0068 16.5 2.5 60 3.7 0.0 5.3 7 0 0 7 7 6 0 Domain of unknown function zf-RRPl_C4 PF17026.5 KFM83390.1 - 0.011 15.8 45.2 0.93 9.6 3.7 5.0 1 1 3 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type ADK_lid PF05191.14 KFM83390.1 - 0.015 15.3 33.0 3.7 7.6 0.8 6.7 4 2 2 6 6 6 0 Adenylate kinase, active site lid zf-MYST PF17772.1 KFM83390.1 - 0.043 13.4 48.8 1.1 8.9 0.3 9.9 6 3 4 10 10 10 0 MYST family zinc finger domain FYVE PF01363.21 KFM83390.1 - 0.15 12.2 67.9 0.11 12.6 9.9 6.1 1 1 2 4 4 4 0 FYVE zinc finger Zf_RING PF16744.5 KFM83390.1 - 0.31 11.2 55.0 12 6.1 0.8 9.9 1 1 5 8 8 8 0 KIAA1045 RING finger zf-Dof PF02701.15 KFM83390.1 - 0.34 11.1 27.8 6.1 7.1 0.1 7.5 1 1 5 7 7 7 0 Dof domain, zinc finger CBP_BcsQ PF06564.12 KFM83390.1 - 0.55 9.7 3.4 27 4.2 0.1 3.0 2 1 0 3 3 3 0 Cellulose biosynthesis protein BcsQ C5HCH PF17982.1 KFM83390.1 - 0.72 10.1 57.0 7.6 6.8 3.4 9.9 6 2 4 10 10 10 0 NSD Cys-His rich domain zf-C2H2_9 PF16293.5 KFM83390.1 - 1.4 8.9 49.1 9.5 6.1 0.8 9.7 1 1 9 10 10 10 0 C2H2 type zinc-finger (1 copy) RecR PF02132.15 KFM83390.1 - 3.1 7.4 48.8 10 5.8 4.1 9.4 7 3 0 7 7 7 0 RecR protein Prok-RING_1 PF14446.6 KFM83390.1 - 3.5 7.6 50.5 8.7 6.4 0.2 9.9 9 1 0 9 9 9 0 Prokaryotic RING finger family 1 TRAF6_Z2 PF18048.1 KFM83390.1 - 4.5 7.5 55.7 0.55 10.4 0.3 9.5 10 0 0 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 HNH_5 PF14279.6 KFM83390.1 - 8.1 6.4 52.5 3.3 7.6 0.1 9.1 5 3 2 7 7 7 0 HNH endonuclease zf-C2H2_4 PF13894.6 KFM83391.1 - 1.2e-05 25.8 2.1 1.2e-05 25.8 2.1 1.9 1 1 1 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM83391.1 - 0.00034 20.9 3.4 0.00034 20.9 3.4 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.7 KFM83391.1 - 0.0041 17.5 2.8 0.0079 16.6 2.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-UBP PF02148.19 KFM83391.1 - 0.045 14.1 2.7 0.047 14.0 2.7 1.1 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein C5HCH PF17982.1 KFM83391.1 - 0.058 13.5 0.8 0.066 13.4 0.8 1.1 1 0 0 1 1 1 0 NSD Cys-His rich domain zf-C2H2_9 PF16293.5 KFM83391.1 - 0.13 12.1 2.5 0.15 12.0 2.5 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) UPF1_Zn_bind PF09416.10 KFM83391.1 - 0.19 11.7 3.1 0.19 11.7 3.1 1.0 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) SK_channel PF03530.14 KFM83392.1 - 2.1e-06 27.7 1.3 2.1e-06 27.7 1.3 1.0 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Gemin6 PF06372.12 KFM83394.1 - 4.8e-23 81.5 0.2 6.2e-23 81.2 0.2 1.1 1 0 0 1 1 1 1 Gemin6 protein AD PF09793.9 KFM83394.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain DDE_Tnp_1_7 PF13843.6 KFM83396.1 - 0.0071 15.7 0.0 0.0072 15.7 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 ubiquitin PF00240.23 KFM83402.1 - 0.057 13.2 0.1 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin family Ubiquitin_2 PF14560.6 KFM83402.1 - 0.094 13.2 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF4116 PF13475.6 KFM83404.1 - 0.048 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF5395 PF17373.2 KFM83404.1 - 0.13 12.9 0.0 0.7 10.6 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5395) Ribosomal_L27e PF01777.18 KFM83405.1 - 7.4e-40 135.2 10.1 9.8e-40 134.8 10.1 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KFM83405.1 - 7.7e-06 25.7 1.1 1.8e-05 24.5 1.1 1.6 1 0 0 1 1 1 1 KOW motif zf-CCCH PF00642.24 KFM83406.1 - 3.2e-21 74.7 26.0 2.7e-07 30.3 0.4 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM83406.1 - 5.6e-20 70.7 32.4 9.8e-07 28.6 2.4 5.3 4 1 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 KFM83406.1 - 3.5e-18 65.0 29.8 1.2e-06 28.2 1.2 4.8 4 0 0 4 4 4 4 CCCH-type zinc finger Torus PF16131.5 KFM83406.1 - 3.4e-12 47.0 9.2 0.038 14.7 0.6 4.5 3 1 1 4 4 4 4 Torus domain zf-CCCH_3 PF15663.5 KFM83406.1 - 1.5e-08 34.8 11.5 1.5e-08 34.8 0.6 3.1 3 0 0 3 3 3 1 Zinc-finger containing family zf-C3HC4 PF00097.25 KFM83406.1 - 9.8e-08 31.8 2.5 6.9e-07 29.0 2.5 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 KFM83406.1 - 1.4e-07 31.7 29.4 0.0044 17.4 1.3 4.9 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-RING_UBOX PF13445.6 KFM83406.1 - 2.1e-05 24.5 0.9 0.0001 22.2 0.9 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFM83406.1 - 2.2e-05 24.7 4.7 2.2e-05 24.7 4.7 3.9 3 2 1 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM83406.1 - 0.0015 18.3 4.0 0.0015 18.3 4.0 3.5 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM83406.1 - 0.0039 17.1 5.1 0.0039 17.1 5.1 3.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFM83406.1 - 0.05 13.4 4.2 0.18 11.6 4.2 2.1 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KFM83406.1 - 4.1 7.6 13.1 0.15 12.2 4.8 3.1 3 1 0 3 3 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFM83406.1 - 6.2 7.2 20.0 0.08 13.2 7.3 3.7 3 1 1 4 4 4 0 RING-H2 zinc finger domain zf-H2C2_2 PF13465.6 KFM83407.1 - 3.3e-69 226.4 99.2 1.9e-08 34.3 0.8 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83407.1 - 1.2e-50 167.2 107.6 7.5e-06 26.1 2.5 12.7 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83407.1 - 5.5e-35 117.0 97.3 0.0001 22.8 1.8 12.0 12 0 0 12 12 12 10 C2H2-type zinc finger zf-met PF12874.7 KFM83407.1 - 3.6e-30 103.4 83.8 0.00065 20.0 0.7 12.3 12 0 0 12 12 12 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83407.1 - 1.5e-22 79.3 70.6 0.0029 17.8 0.8 12.5 12 1 1 13 13 13 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83407.1 - 3.9e-17 61.8 70.9 0.00083 19.3 0.2 12.0 12 0 0 12 12 12 9 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM83407.1 - 7.9e-15 54.3 71.9 0.0044 16.7 1.7 11.7 11 0 0 11 11 11 8 C2H2-type zinc-finger domain C1_1 PF00130.22 KFM83407.1 - 8.6e-06 25.5 51.3 2.5 8.1 0.4 9.4 3 2 5 9 9 9 5 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFM83407.1 - 3.7e-05 23.4 21.0 3.1 7.7 0.0 7.6 3 1 6 9 9 9 2 GAGA factor zf-C2HC_2 PF13913.6 KFM83407.1 - 6.7e-05 22.7 36.8 3.3 7.7 0.3 9.8 10 0 0 10 10 10 2 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFM83407.1 - 7.9e-05 22.9 76.5 0.28 11.5 1.6 10.3 1 1 9 10 10 10 4 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFM83407.1 - 0.0001 22.1 47.1 0.36 10.7 0.7 10.7 4 1 8 12 12 12 2 C2H2 type zinc-finger (1 copy) zf-RRPl_C4 PF17026.5 KFM83407.1 - 0.00073 19.6 41.8 0.23 11.6 3.8 4.5 1 1 3 4 4 4 3 Putative ribonucleoprotein zinc-finger pf C4 type ADK_lid PF05191.14 KFM83407.1 - 0.0012 18.7 30.3 0.23 11.5 0.0 7.0 2 1 7 9 9 9 2 Adenylate kinase, active site lid BolA PF01722.18 KFM83407.1 - 0.023 15.0 23.8 11 6.4 1.3 7.3 1 1 4 6 6 6 0 BolA-like protein DUF2256 PF10013.9 KFM83407.1 - 0.039 14.1 33.8 23 5.2 0.1 9.8 11 0 0 11 11 10 0 Uncharacterized protein conserved in bacteria (DUF2256) Mga PF05043.13 KFM83407.1 - 0.068 13.8 4.2 2.5 8.7 0.0 3.8 4 0 0 4 4 4 0 Mga helix-turn-helix domain zf-CHCC PF10276.9 KFM83407.1 - 0.2 11.7 16.3 67 3.7 0.0 8.3 10 0 0 10 10 10 0 Zinc-finger domain FYVE PF01363.21 KFM83407.1 - 1.1 9.4 55.3 0.44 10.7 9.5 6.2 1 1 5 6 6 6 0 FYVE zinc finger IF3_N PF05198.16 KFM83407.1 - 2.3 8.6 3.7 19 5.6 0.1 3.7 5 1 0 5 5 4 0 Translation initiation factor IF-3, N-terminal domain Scramblase PF03803.15 KFM83407.1 - 2.3 7.4 7.9 4.1 6.6 0.7 2.6 1 1 1 2 2 2 0 Scramblase zf-Sec23_Sec24 PF04810.15 KFM83407.1 - 4.9 7.3 35.1 14 5.8 0.9 9.1 7 3 3 10 10 10 0 Sec23/Sec24 zinc finger zinc_ribbon_15 PF17032.5 KFM83407.1 - 6.5 7.6 41.6 3.2 8.6 2.2 5.8 1 1 1 4 4 3 0 zinc-ribbon family Histone PF00125.24 KFM83408.1 - 1.9e-25 89.7 1.0 2.2e-25 89.5 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KFM83408.1 - 0.018 15.6 0.8 0.022 15.3 0.8 1.1 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Alg6_Alg8 PF03155.15 KFM83411.1 - 7e-54 183.6 1.5 8e-54 183.4 1.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Alg6_Alg8 PF03155.15 KFM83412.1 - 5.6e-18 65.2 4.9 6.1e-18 65.1 4.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ATP_bind_3 PF01171.20 KFM83414.1 - 3.7e-15 56.1 0.0 8.1e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 PP-loop family OB_RNB PF08206.11 KFM83414.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain Cullin PF00888.22 KFM83415.1 - 1.1e-33 116.8 2.5 1.2e-33 116.6 2.5 1.0 1 0 0 1 1 1 1 Cullin family Tup_N PF08581.10 KFM83416.1 - 0.0092 16.3 2.7 0.016 15.5 2.7 1.5 1 1 0 1 1 1 1 Tup N-terminal Tox-REase-5 PF15648.6 KFM83416.1 - 0.038 14.5 0.3 0.05 14.1 0.3 1.3 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 Mto2_bdg PF12808.7 KFM83416.1 - 0.13 12.6 1.0 0.13 12.6 1.0 2.5 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3886 PF13025.6 KFM83416.1 - 2.7 8.2 10.6 0.61 10.3 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) ANF_receptor PF01094.28 KFM83420.1 - 4.5e-10 39.2 0.0 5e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region SLC12 PF03522.15 KFM83421.1 - 1e-107 360.9 0.1 1.1e-107 360.7 0.1 1.0 1 0 0 1 1 1 1 Solute carrier family 12 Dynein_C PF18199.1 KFM83422.1 - 0.00035 19.9 0.0 0.00035 19.9 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain EGF_MSP1_1 PF12946.7 KFM83423.1 - 2.1 8.4 18.0 0.15 12.1 6.8 2.6 2 1 0 2 2 2 0 MSP1 EGF domain 1 EGF_3 PF12947.7 KFM83423.1 - 2.8 8.2 16.7 1.4 9.1 6.2 3.0 2 2 0 2 2 2 0 EGF domain EGF PF00008.27 KFM83423.1 - 7 7.0 21.3 1.1 9.6 1.2 3.5 3 1 1 4 4 4 0 EGF-like domain EB PF01683.18 KFM83423.1 - 8.8 6.7 22.9 6.6 7.1 8.8 2.5 1 1 1 2 2 2 0 EB module zf-H2C2_2 PF13465.6 KFM83424.1 - 4.8e-55 181.7 77.3 6e-09 35.9 1.2 10.1 10 0 0 10 10 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83424.1 - 2.1e-39 131.8 88.4 7.6e-06 26.1 1.3 9.2 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83424.1 - 9.4e-32 106.9 79.1 0.0003 21.4 0.7 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 KFM83424.1 - 3.1e-13 49.6 75.2 0.0037 17.6 0.4 10.4 11 0 0 11 11 10 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83424.1 - 5e-13 48.7 64.9 0.053 13.5 1.0 9.7 9 1 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM83424.1 - 1.1e-08 35.1 52.9 0.005 17.1 0.3 9.2 8 2 1 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM83424.1 - 2.1e-08 33.8 62.6 0.0018 18.0 2.9 9.8 9 0 0 9 9 8 5 C2H2-type zinc-finger domain GAGA PF09237.11 KFM83424.1 - 5.1e-06 26.2 22.4 0.49 10.2 0.2 6.6 3 2 4 7 7 7 3 GAGA factor BolA PF01722.18 KFM83424.1 - 0.00013 22.2 11.8 0.19 12.0 0.0 4.9 3 2 0 4 4 4 2 BolA-like protein DUF4825 PF16107.5 KFM83424.1 - 0.0041 17.2 0.0 13 6.0 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4825) Baculo_IE-1 PF05290.11 KFM83424.1 - 0.0046 16.9 30.3 5.8 6.9 0.2 7.6 1 1 6 8 8 8 2 Baculovirus immediate-early protein (IE-0) zf-C2H2_11 PF16622.5 KFM83424.1 - 0.023 14.4 0.1 0.023 14.4 0.1 8.3 8 0 0 8 8 7 0 zinc-finger C2H2-type HTH_18 PF12833.7 KFM83424.1 - 0.18 12.1 0.4 4.4 7.6 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain zf-C2H2_2 PF12756.7 KFM83424.1 - 0.4 11.1 59.6 4.1 7.8 16.2 8.1 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFM83424.1 - 1 10.1 39.5 2.5 8.9 3.7 5.1 1 1 7 8 8 8 0 zinc-ribbon family VATC PF18716.1 KFM83424.1 - 3.4 7.6 38.2 8.4 6.3 0.1 8.8 8 1 1 9 9 9 0 Vms1-associating treble clef domain zf-Sec23_Sec24 PF04810.15 KFM83424.1 - 9.9 6.3 43.1 2.2 8.4 0.9 8.2 7 2 2 9 9 9 0 Sec23/Sec24 zinc finger Acyl-CoA_dh_1 PF00441.24 KFM83428.1 - 4.4e-32 111.4 2.0 5.8e-32 111.0 2.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFM83428.1 - 1.1e-24 86.4 0.1 2.6e-24 85.3 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM83428.1 - 9.6e-11 42.1 0.5 1.9e-10 41.1 0.5 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM83428.1 - 4.9e-10 40.1 0.0 1.5e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain DUF1639 PF07797.14 KFM83429.1 - 0.03 14.3 1.0 0.03 14.3 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) DDE_Tnp_4 PF13359.6 KFM83430.1 - 2.9e-33 114.8 0.0 3.5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM83430.1 - 6.4e-12 45.5 0.0 1.2e-10 41.3 0.0 2.3 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFM83430.1 - 3.6e-05 23.5 0.0 0.0046 16.6 0.0 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 KFM83430.1 - 0.027 14.8 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain zf-C2H2_4 PF13894.6 KFM83432.1 - 6.8e-05 23.4 1.6 6.8e-05 23.4 1.6 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM83432.1 - 0.013 15.9 1.4 0.013 15.9 1.4 2.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFM83432.1 - 0.013 15.4 2.4 0.013 15.4 2.4 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf_Hakai PF18408.1 KFM83432.1 - 4.5 7.1 6.8 17 5.2 0.5 2.3 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain MULE PF10551.9 KFM83433.1 - 2.1e-07 31.3 1.3 2.8e-06 27.7 0.2 2.6 1 1 1 2 2 2 1 MULE transposase domain zf-C2H2_3rep PF18868.1 KFM83433.1 - 0.0021 18.7 8.4 0.011 16.4 8.2 2.4 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 KFM83433.1 - 0.0034 17.7 2.0 0.0034 17.7 2.0 4.4 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83433.1 - 0.032 15.1 1.6 0.032 15.1 1.6 4.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM83433.1 - 0.89 9.9 16.0 1.6 9.1 0.5 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KFM83433.1 - 9.6 6.3 16.4 4.4 7.4 2.5 3.2 1 1 1 2 2 2 0 BED zinc finger SOCS PF12610.8 KFM83434.1 - 0.13 12.7 0.5 19 5.7 0.0 2.9 3 0 0 3 3 3 0 Suppressor of cytokine signalling DUF4604 PF15377.6 KFM83434.1 - 0.24 11.8 0.4 6.8 7.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) MRP-L51 PF10244.9 KFM83434.1 - 0.24 11.6 0.0 15 5.9 0.0 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit Lig_chan PF00060.26 KFM83436.1 - 1.5e-46 158.0 3.6 1.8e-46 157.7 3.6 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFM83436.1 - 1.1e-09 38.5 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFM83436.1 - 0.003 17.0 0.0 0.003 17.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 KFM83436.1 - 3.9 7.5 8.9 22 5.1 9.0 2.2 1 1 0 1 1 1 0 Ion channel PRE_C2HC PF07530.11 KFM83437.1 - 2.8e-15 56.2 0.3 6.6e-15 55.0 0.3 1.7 1 0 0 1 1 1 1 Associated with zinc fingers GIT_CC PF16559.5 KFM83437.1 - 0.02 14.7 0.4 0.064 13.1 0.4 1.9 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Bac_RepA_C PF18008.1 KFM83437.1 - 0.03 14.7 2.0 0.03 14.7 2.0 2.7 3 1 1 4 4 4 0 Replication initiator protein A C-terminal domain Mto2_bdg PF12808.7 KFM83437.1 - 0.048 14.0 0.3 0.16 12.2 0.3 1.9 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4692 PF15763.5 KFM83437.1 - 3 8.3 8.5 8.7 6.8 7.9 2.0 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Myb_DNA-bind_5 PF13873.6 KFM83439.1 - 2.5e-13 49.9 0.0 3.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFM83439.1 - 0.0011 19.3 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFM83439.1 - 0.0029 17.9 0.0 0.0038 17.5 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Phage_int_SAM_2 PF12834.7 KFM83439.1 - 0.014 16.0 0.0 0.027 15.2 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal Myb_DNA-binding PF00249.31 KFM83439.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.5 1 1 0 1 1 1 0 Myb-like DNA-binding domain DUF3899 PF13038.6 KFM83440.1 - 0.0032 17.9 1.9 0.004 17.6 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3899) Peptidase_S49_N PF08496.10 KFM83440.1 - 0.0054 16.8 7.1 0.0068 16.5 7.1 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal SLD3 PF08639.10 KFM83440.1 - 0.0063 15.3 4.4 0.0075 15.1 4.4 1.0 1 0 0 1 1 1 1 DNA replication regulator SLD3 Jak1_Phl PF17887.1 KFM83440.1 - 0.0095 15.9 0.8 0.01 15.8 0.8 1.1 1 0 0 1 1 1 1 Jak1 pleckstrin homology-like domain AP3D1 PF06375.11 KFM83440.1 - 0.015 15.5 12.5 0.019 15.2 12.5 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 CrgA PF06781.12 KFM83440.1 - 0.027 14.5 0.7 0.041 13.9 0.7 1.2 1 0 0 1 1 1 0 Cell division protein CrgA Orf78 PF06024.12 KFM83440.1 - 0.027 14.7 0.5 0.037 14.3 0.5 1.2 1 0 0 1 1 1 0 Orf78 (ac78) SARAF PF06682.12 KFM83440.1 - 0.043 13.5 0.5 0.053 13.2 0.5 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis VKG_Carbox PF05090.14 KFM83440.1 - 0.045 12.6 0.9 0.049 12.5 0.9 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase GWT1 PF06423.12 KFM83440.1 - 0.05 13.7 0.3 0.062 13.4 0.3 1.2 1 0 0 1 1 1 0 GWT1 O-ag_pol_Wzy PF14296.6 KFM83440.1 - 0.074 11.7 4.7 0.087 11.5 4.7 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DcuA_DcuB PF03605.14 KFM83440.1 - 0.16 10.9 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter AgrB PF04647.15 KFM83440.1 - 0.28 10.5 10.5 0.31 10.3 9.7 1.5 1 1 0 1 1 1 0 Accessory gene regulator B DUF4604 PF15377.6 KFM83440.1 - 0.34 11.3 12.3 0.37 11.2 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SART-1 PF03343.13 KFM83440.1 - 0.58 8.7 11.5 0.65 8.5 11.5 1.0 1 0 0 1 1 1 0 SART-1 family TSGP1 PF07771.11 KFM83440.1 - 0.64 10.2 8.8 0.75 10.0 8.8 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 ERK-JNK_inhib PF15002.6 KFM83440.1 - 1.1 8.9 12.8 1.5 8.5 12.8 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor SR-25 PF10500.9 KFM83440.1 - 4.8 6.7 24.3 6.1 6.4 24.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAMP4 PF06624.12 KFM83440.1 - 9.9 6.3 12.8 32 4.7 12.7 1.8 1 1 0 1 1 1 0 Ribosome associated membrane protein RAMP4 ELO PF01151.18 KFM83442.1 - 0.0027 17.3 0.0 0.0033 17.0 0.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Pkinase PF00069.25 KFM83443.1 - 5.3e-38 130.9 0.0 7.3e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PX PF00787.24 KFM83443.1 - 2.1e-23 82.5 0.8 3.8e-23 81.6 0.2 1.7 2 0 0 2 2 2 1 PX domain Pkinase_Tyr PF07714.17 KFM83443.1 - 7.3e-18 64.8 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KFM83443.1 - 5.7e-05 22.8 0.0 0.028 14.0 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 STAT1_TAZ2bind PF12162.8 KFM83443.1 - 0.12 12.0 0.5 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain MKLP1_Arf_bdg PF16540.5 KFM83444.1 - 1.9e-23 82.6 0.9 1.9e-23 82.6 0.9 2.7 2 1 0 2 2 2 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Kinesin PF00225.23 KFM83444.1 - 4.4e-20 71.9 0.0 4.4e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Cnn_1N PF07989.11 KFM83444.1 - 0.011 15.9 3.7 0.011 15.9 3.7 3.1 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Noelin-1 PF12308.8 KFM83444.1 - 0.12 12.3 10.8 0.28 11.2 5.3 2.8 2 1 0 2 2 2 0 Neurogenesis glycoprotein Exonuc_VII_L PF02601.15 KFM83444.1 - 4.6 6.7 15.2 8.7 5.8 15.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit COX1 PF00115.20 KFM83445.1 - 3.3e-21 75.7 0.4 3.6e-21 75.5 0.4 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I PGF-CTERM PF18204.1 KFM83445.1 - 2.2 8.4 6.5 17 5.6 0.2 2.3 2 0 0 2 2 2 0 PGF-CTERM motif MOR2-PAG1_N PF14222.6 KFM83446.1 - 8.3e-82 275.9 2.8 1.1e-81 275.5 2.8 1.1 1 0 0 1 1 1 1 Cell morphogenesis N-terminal DUF5321 PF17254.2 KFM83446.1 - 0.049 13.1 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5321) Caerin_1 PF07440.12 KFM83446.1 - 0.11 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Caerin 1 protein MOR2-PAG1_mid PF14228.6 KFM83447.1 - 1.9e-17 62.3 0.4 3.4e-09 35.0 0.0 3.0 1 1 2 3 3 3 3 Cell morphogenesis central region AHD PF17793.1 KFM83447.1 - 0.017 14.9 0.2 0.056 13.3 0.0 1.9 2 0 0 2 2 2 0 ANC1 homology domain (AHD) MOR2-PAG1_C PF14225.6 KFM83448.1 - 1.2e-75 254.7 2.7 1.2e-75 254.7 2.7 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KFM83448.1 - 5.1e-17 60.9 2.7 4.1e-10 38.0 0.2 2.2 2 0 0 2 2 2 2 Cell morphogenesis central region I-set PF07679.16 KFM83449.1 - 1.1e-18 67.0 0.0 8.9e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM83449.1 - 8.4e-17 61.5 0.2 2e-09 37.9 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM83449.1 - 7.3e-12 45.3 0.0 8.7e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM83449.1 - 8.6e-10 38.8 0.0 0.00032 21.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM83449.1 - 3.4e-08 33.6 0.1 0.009 16.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFM83449.1 - 0.0002 21.3 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFM83449.1 - 0.0041 16.6 0.0 0.008 15.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Receptor_2B4 PF11465.8 KFM83449.1 - 0.011 16.0 0.0 0.056 13.7 0.0 2.1 1 1 0 2 2 2 0 Natural killer cell receptor 2B4 Ig_5 PF16681.5 KFM83449.1 - 0.035 14.5 0.0 3.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFM83449.1 - 0.044 14.2 0.0 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin C1-set domain zf-H2C2_2 PF13465.6 KFM83453.1 - 1.6e-81 265.4 67.2 7e-09 35.7 0.4 11.1 11 0 0 11 11 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83453.1 - 2.8e-56 185.0 84.1 2.4e-06 27.7 1.8 10.6 11 0 0 11 11 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83453.1 - 1.3e-36 122.0 77.0 0.0016 19.1 0.7 10.6 11 0 0 11 11 10 10 C2H2-type zinc finger zf-met PF12874.7 KFM83453.1 - 1.1e-34 117.8 79.7 0.00032 21.0 3.0 10.3 10 0 0 10 10 10 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83453.1 - 5.6e-23 80.7 54.7 0.021 15.1 0.4 10.4 10 0 0 10 10 10 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83453.1 - 1.7e-20 72.5 59.1 0.00098 19.1 0.8 10.8 10 0 0 10 10 10 8 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 KFM83453.1 - 1e-14 54.2 38.8 0.065 13.3 0.2 10.0 2 2 8 10 10 10 5 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM83453.1 - 7e-14 51.3 33.6 0.97 9.4 0.2 10.8 10 1 0 10 10 10 4 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFM83453.1 - 3.5e-11 42.7 59.2 0.13 12.1 0.4 11.1 11 0 0 11 11 11 7 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 KFM83453.1 - 2.9e-07 30.2 46.1 0.93 9.4 0.1 10.0 2 2 8 10 10 10 4 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KFM83453.1 - 7.7e-07 29.1 38.7 4.4 7.5 0.1 9.9 10 0 0 10 10 10 1 DBF zinc finger GAGA PF09237.11 KFM83453.1 - 1.3e-06 28.1 16.4 0.85 9.5 0.0 7.7 2 2 7 9 9 9 3 GAGA factor BolA PF01722.18 KFM83453.1 - 4.3e-06 26.9 17.5 0.33 11.2 0.3 6.4 2 2 3 6 6 5 1 BolA-like protein zf-C2H2_11 PF16622.5 KFM83453.1 - 8.4e-06 25.4 50.8 0.041 13.6 0.1 9.0 10 0 0 10 10 10 5 zinc-finger C2H2-type zf-RRPl_C4 PF17026.5 KFM83453.1 - 1.7e-05 24.9 40.5 0.038 14.1 5.5 4.8 1 1 4 5 5 5 4 Putative ribonucleoprotein zinc-finger pf C4 type DUF2256 PF10013.9 KFM83453.1 - 9.9e-05 22.4 33.0 16 5.7 0.2 9.9 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFM83453.1 - 0.0019 18.9 39.0 0.68 10.7 2.7 5.3 1 1 2 5 5 5 2 zinc-ribbon family zf-MYST PF17772.1 KFM83453.1 - 0.011 15.4 41.0 2 8.1 0.6 9.1 4 3 5 9 9 9 0 MYST family zinc finger domain Tox-HNH-HHH PF15637.6 KFM83453.1 - 0.019 15.1 4.0 9 6.5 0.0 4.3 2 1 3 5 5 5 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Zn-ribbon_8 PF09723.10 KFM83453.1 - 0.027 14.6 33.4 0.9 9.7 0.7 6.6 2 2 7 9 9 9 0 Zinc ribbon domain Alk_phosphatase PF00245.20 KFM83453.1 - 0.071 12.0 1.0 0.34 9.8 0.2 2.3 2 1 0 2 2 2 0 Alkaline phosphatase C1_4 PF07975.12 KFM83453.1 - 0.15 12.3 46.9 0.48 10.7 1.9 7.3 1 1 7 9 9 9 0 TFIIH C1-like domain zf-CHCC PF10276.9 KFM83453.1 - 0.19 11.8 20.7 4.7 7.4 0.0 7.9 10 0 0 10 10 9 0 Zinc-finger domain IGPD PF00475.18 KFM83453.1 - 0.28 11.5 13.4 1.6 9.1 0.3 5.2 3 2 3 7 7 7 0 Imidazoleglycerol-phosphate dehydratase Complex1_49kDa PF00346.19 KFM83453.1 - 0.28 10.2 2.0 6.1 5.9 0.0 3.0 1 1 4 5 5 5 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit ADK_lid PF05191.14 KFM83453.1 - 0.29 11.2 47.7 1.3 9.1 2.8 7.3 4 3 3 7 7 7 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFM83453.1 - 0.78 10.1 68.6 3.1 8.2 1.5 9.6 1 1 8 9 9 8 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFM83453.1 - 1.6 8.4 38.0 18 5.0 0.1 9.4 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 KFM83453.1 - 2.2 8.5 46.7 4.5 7.5 6.1 5.8 1 1 3 4 4 3 0 FYVE zinc finger zf-FPG_IleRS PF06827.14 KFM83453.1 - 2.5 8.0 32.6 29 4.6 0.1 9.3 10 0 0 10 10 10 0 Zinc finger found in FPG and IleRS Zf_RING PF16744.5 KFM83453.1 - 3.4 7.9 41.9 37 4.5 2.8 9.2 1 1 7 8 8 8 0 KIAA1045 RING finger DUF3268 PF11672.8 KFM83453.1 - 3.5 8.0 26.6 0.48 10.8 0.4 5.1 2 2 3 6 6 6 0 zinc-finger-containing domain Zn_ribbon_SprT PF17283.2 KFM83453.1 - 3.7 7.5 31.1 11 6.0 0.3 8.2 3 2 5 8 8 8 0 SprT-like zinc ribbon domain DUF5330 PF17264.2 KFM83453.1 - 8.9 6.4 23.3 3.4 7.7 0.1 7.5 9 0 0 9 9 9 0 Family of unknown function (DUF5330) Fe_hyd_SSU PF02256.17 KFM83454.1 - 0.19 11.8 0.6 0.19 11.8 0.6 1.5 2 0 0 2 2 2 0 Iron hydrogenase small subunit APG6_N PF17675.1 KFM83456.1 - 0.043 14.3 0.4 0.043 14.3 0.4 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region MADF_DNA_bdg PF10545.9 KFM83456.1 - 0.27 11.6 2.8 0.65 10.4 0.1 2.6 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RasGEF PF00617.19 KFM83457.1 - 1.9e-13 51.0 0.0 3.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain SH2 PF00017.24 KFM83457.1 - 1.6e-08 34.5 0.0 3.5e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Leader_Erm PF08253.11 KFM83457.1 - 0.16 12.3 0.1 0.57 10.6 0.1 2.0 1 0 0 1 1 1 0 Erm Leader peptide Peptidase_C12 PF01088.21 KFM83458.1 - 3.4e-69 232.8 0.2 1.3e-68 230.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFM83458.1 - 3.8e-19 68.3 3.8 6.8e-19 67.5 3.8 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases DNA_repr_REX1B PF14966.6 KFM83458.1 - 0.18 12.5 2.8 0.23 12.1 0.7 2.0 2 0 0 2 2 2 0 DNA repair REX1-B HU-CCDC81_euk_2 PF18289.1 KFM83460.1 - 0.12 12.5 0.1 11 6.2 0.0 2.3 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 Transposase_1 PF01359.18 KFM83464.1 - 0.0036 17.1 1.1 0.0045 16.8 0.2 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) Clp1 PF06807.14 KFM83469.1 - 2.4e-12 47.3 0.0 2.4e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 Nkap_C PF06047.11 KFM83472.1 - 1.3e-19 70.1 0.4 1.4e-19 70.1 0.4 1.0 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain HSP70 PF00012.20 KFM83474.1 - 2.9e-18 65.4 0.3 3.1e-18 65.3 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein Chitin_bind_4 PF00379.23 KFM83475.1 - 9.4e-12 45.3 6.1 1.3e-11 44.8 6.1 1.2 1 0 0 1 1 1 1 Insect cuticle protein Med6 PF04934.14 KFM83477.1 - 1.6e-11 44.1 0.3 1.6e-11 44.1 0.3 1.0 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF2070 PF09843.9 KFM83479.1 - 5.3 5.2 11.6 5.8 5.1 11.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ank_4 PF13637.6 KFM83481.1 - 8.1e-05 23.1 0.0 8.8e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM83481.1 - 0.00045 20.5 0.1 0.61 10.5 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM83481.1 - 0.0011 19.5 0.0 0.0012 19.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM83481.1 - 0.0028 18.0 0.0 0.23 12.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KFM83481.1 - 0.034 14.7 0.0 2.7 8.8 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeat DUF2688 PF10892.8 KFM83482.1 - 0.03 13.8 0.3 0.041 13.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) PDEase_I PF00233.19 KFM83482.1 - 0.15 11.8 2.2 0.17 11.6 2.2 1.0 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase HSP70 PF00012.20 KFM83484.1 - 2.5e-64 217.6 0.0 2.7e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 KFM83486.1 - 2.8e-83 280.1 0.1 3.2e-83 279.9 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF1894 PF08979.11 KFM83486.1 - 0.052 13.9 0.0 3.7 8.0 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1894) MreB_Mbl PF06723.13 KFM83486.1 - 0.085 11.7 0.1 7.8 5.2 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Somatomedin_B PF01033.17 KFM83487.1 - 0.01 16.2 11.8 0.01 16.2 11.8 3.1 3 2 0 3 3 3 0 Somatomedin B domain CRAL_TRIO_N PF03765.15 KFM83489.1 - 0.066 13.4 0.2 0.099 12.8 0.2 1.4 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain zf-CCHC PF00098.23 KFM83491.1 - 2.4e-05 24.2 14.7 0.0044 17.0 2.2 3.2 2 1 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KFM83491.1 - 0.015 15.1 2.8 0.015 15.1 2.8 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-Paramyx-P PF13008.7 KFM83491.1 - 8.3 6.0 10.0 2.1 7.8 1.9 2.9 2 1 1 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein DUF2039 PF10217.9 KFM83494.1 - 4.2e-15 55.8 5.0 5.2e-15 55.5 5.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) STPPase_N PF16891.5 KFM83494.1 - 0.047 14.1 0.1 0.077 13.5 0.1 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-H2C2_2 PF13465.6 KFM83495.1 - 3.2e-35 119.0 35.5 1.6e-08 34.6 2.3 7.1 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83495.1 - 1.7e-29 100.6 35.3 1.6e-05 25.1 1.5 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83495.1 - 1.1e-23 81.9 33.7 4.6e-05 23.9 1.0 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFM83495.1 - 8.2e-17 61.0 36.3 0.00098 19.4 0.3 6.3 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83495.1 - 5.2e-11 42.5 32.1 0.0047 17.2 0.9 6.7 4 2 2 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFM83495.1 - 9.1e-10 38.3 46.5 0.00015 21.7 0.8 7.7 6 4 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFM83495.1 - 2e-06 27.5 27.2 0.12 12.2 0.3 6.1 6 0 0 6 6 6 4 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFM83495.1 - 2.9e-06 27.2 16.8 0.0025 17.8 0.1 5.4 2 2 2 5 5 5 1 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 KFM83495.1 - 1.8e-05 24.5 13.5 0.097 12.6 0.2 5.2 5 0 0 5 5 5 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KFM83495.1 - 0.00011 22.4 28.5 0.0064 16.8 5.7 4.2 1 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFM83495.1 - 0.00031 20.3 18.8 0.89 9.2 0.5 6.0 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFM83495.1 - 0.00088 19.6 32.5 0.19 12.1 1.3 5.7 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KFM83495.1 - 0.0015 18.5 11.1 0.035 14.1 0.4 3.9 3 1 1 4 4 4 1 Adenylate kinase, active site lid DUF2256 PF10013.9 KFM83495.1 - 0.0083 16.2 11.8 3.7 7.8 0.1 5.4 6 0 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-FCS PF06467.14 KFM83495.1 - 0.018 15.0 9.7 2.7 8.0 0.3 4.7 3 2 1 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_15 PF17032.5 KFM83495.1 - 0.024 15.4 14.3 0.13 13.0 2.0 3.1 1 1 1 3 3 3 0 zinc-ribbon family zf-C2H2_9 PF16293.5 KFM83495.1 - 0.035 13.9 18.3 12 5.8 0.1 5.6 2 2 4 6 6 6 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 KFM83495.1 - 0.047 13.7 10.5 1.3 9.1 2.6 3.1 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 KFM83495.1 - 0.096 12.8 23.0 1.4e+04 -3.7 23.0 4.3 1 1 0 1 1 0 0 FYVE zinc finger DUF3268 PF11672.8 KFM83495.1 - 0.21 11.9 5.7 1.2 9.5 0.5 2.6 1 1 0 2 2 2 0 zinc-finger-containing domain IGPD PF00475.18 KFM83495.1 - 0.21 11.9 3.9 1.3 9.4 0.6 2.6 2 1 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase DUF5330 PF17264.2 KFM83495.1 - 0.29 11.2 1.7 32 4.6 0.0 3.6 4 0 0 4 4 3 0 Family of unknown function (DUF5330) zf-UBP PF02148.19 KFM83495.1 - 0.43 11.0 29.2 21 5.5 1.0 4.2 1 1 2 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein zinc_ribbon_4 PF13717.6 KFM83495.1 - 0.5 10.3 11.9 14 5.7 0.1 5.0 5 0 0 5 5 5 0 zinc-ribbon domain zf-HIT PF04438.16 KFM83495.1 - 0.74 9.7 18.2 7.4 6.5 0.2 5.1 5 0 0 5 5 5 0 HIT zinc finger zf-C2H2_8 PF15909.5 KFM83495.1 - 1.1 9.5 17.5 2.3 8.6 4.7 3.3 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf-CHCC PF10276.9 KFM83495.1 - 1.4 9.0 10.2 4.2 7.5 1.5 4.3 4 1 0 4 4 4 0 Zinc-finger domain zf-MYST PF17772.1 KFM83495.1 - 2.9 7.6 15.7 27 4.5 0.2 4.9 3 1 2 5 5 5 0 MYST family zinc finger domain Zn-ribbon_8 PF09723.10 KFM83495.1 - 3.3 7.9 15.0 11 6.2 2.2 4.0 1 1 3 4 4 4 0 Zinc ribbon domain GATA PF00320.27 KFM83495.1 - 3.9 7.2 10.6 9.2 6.0 0.1 4.4 5 0 0 5 5 5 0 GATA zinc finger zf-DBF PF07535.12 KFM83495.1 - 5.9 7.1 24.1 12 6.1 0.5 5.7 5 1 1 6 6 6 0 DBF zinc finger TRAF6_Z2 PF18048.1 KFM83495.1 - 6.6 6.9 23.1 7.3 6.8 0.1 5.9 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 HNH_5 PF14279.6 KFM83495.1 - 9.9 6.1 21.5 12 5.8 0.5 5.2 3 1 2 5 5 5 0 HNH endonuclease BCNT PF07572.12 KFM83496.1 - 6.6e-23 80.6 3.7 7.4e-23 80.4 3.7 1.0 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF448 PF04296.13 KFM83496.1 - 0.081 12.8 0.1 0.085 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF448) zf-C2H2_6 PF13912.6 KFM83497.1 - 0.00053 19.9 3.5 0.0011 18.9 3.5 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFM83497.1 - 0.00074 19.8 7.1 0.0017 18.7 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83497.1 - 0.003 18.3 5.0 0.0079 17.0 5.0 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2HE PF16278.5 KFM83497.1 - 0.014 15.8 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 KFM83497.1 - 0.017 14.8 0.2 0.026 14.2 0.2 1.3 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 KFM83497.1 - 0.072 13.6 2.8 12 6.6 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Spc7_N PF15402.6 KFM83497.1 - 0.3 9.3 10.3 0.33 9.2 10.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 AAA PF00004.29 KFM83498.1 - 0.00075 19.9 0.0 0.00075 19.9 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-C2H2_7 PF15269.6 KFM83500.1 - 7.9e-06 25.9 0.1 2e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger zf-H2C2_5 PF13909.6 KFM83500.1 - 0.03 14.1 5.7 0.2 11.4 1.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Mut7-C PF01927.16 KFM83500.1 - 0.087 12.9 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain HeH PF12949.7 KFM83500.1 - 0.1 12.3 0.1 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 HeH/LEM domain zf-C2H2_4 PF13894.6 KFM83500.1 - 3.6 8.7 10.5 0.26 12.3 2.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Helicase_C PF00271.31 KFM83501.1 - 3.1e-19 69.3 0.2 2.2e-18 66.6 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ADIP PF11559.8 KFM83501.1 - 0.0013 18.9 0.2 0.17 11.9 0.0 2.3 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding SF3A3 PF16837.5 KFM83501.1 - 0.067 13.7 0.2 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 COMPASS-Shg1 PF05205.12 KFM83501.1 - 0.083 13.6 1.9 0.084 13.6 0.1 2.0 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 BID PF06393.11 KFM83501.1 - 0.096 12.2 0.2 0.33 10.5 0.1 1.9 1 1 1 2 2 2 0 BH3 interacting domain (BID) Strep_SA_rep PF06696.11 KFM83501.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DivIVA PF05103.13 KFM83501.1 - 0.18 11.9 3.1 11 6.1 0.2 2.7 2 1 0 2 2 2 0 DivIVA protein Lzipper-MIP1 PF14389.6 KFM83501.1 - 0.34 11.3 3.2 11 6.4 0.1 3.3 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 MBDa PF16564.5 KFM83503.1 - 5.9e-25 87.2 3.2 7.1e-25 87.0 3.2 1.1 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD MBD PF01429.19 KFM83503.1 - 5.5e-05 22.8 0.1 6.6e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Methyl-CpG binding domain zf-H2C2_2 PF13465.6 KFM83505.1 - 4.3e-21 74.3 35.1 6.3e-09 35.9 2.7 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83505.1 - 9.4e-21 73.1 30.9 2.3e-05 24.6 0.6 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83505.1 - 1.6e-17 62.7 26.2 0.00023 21.7 0.6 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KFM83505.1 - 4.4e-10 39.6 28.8 0.12 12.9 0.7 5.5 5 1 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM83505.1 - 1.9e-08 34.4 26.8 0.089 13.1 0.1 6.1 5 1 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 KFM83505.1 - 2.4e-06 27.5 6.4 0.9 9.6 0.1 4.3 3 2 1 4 4 4 2 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 KFM83505.1 - 4.8e-05 23.0 18.4 0.03 14.1 0.5 4.3 4 0 0 4 4 4 3 zinc-finger C2H2-type GAGA PF09237.11 KFM83505.1 - 0.0002 21.1 3.3 0.43 10.4 0.1 3.7 2 1 3 5 5 5 2 GAGA factor zf-H2C2_5 PF13909.6 KFM83505.1 - 0.00033 20.4 18.2 0.11 12.3 0.6 4.4 4 0 0 4 4 4 3 C2H2-type zinc-finger domain BolA PF01722.18 KFM83505.1 - 0.00087 19.5 1.2 2.1 8.7 0.1 3.5 1 1 2 3 3 3 1 BolA-like protein zinc_ribbon_15 PF17032.5 KFM83505.1 - 0.0095 16.7 9.3 0.6 10.9 1.1 2.4 1 1 1 2 2 2 2 zinc-ribbon family zf-MYST PF17772.1 KFM83505.1 - 0.017 14.7 16.6 0.23 11.1 0.5 4.1 1 1 3 4 4 4 0 MYST family zinc finger domain zf-FPG_IleRS PF06827.14 KFM83505.1 - 0.035 14.0 2.3 20 5.2 0.0 3.9 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS C1_1 PF00130.22 KFM83505.1 - 0.036 13.9 17.1 1.4 8.9 4.4 4.0 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-C2H2_12 PF18112.1 KFM83505.1 - 0.049 14.1 21.1 1.9 9.0 1.0 5.4 5 1 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain FYDLN_acid PF09538.10 KFM83505.1 - 0.054 14.2 2.6 16 6.2 0.5 3.5 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) Zf_RING PF16744.5 KFM83505.1 - 0.055 13.6 14.2 6.7 6.9 0.2 4.7 1 1 3 4 4 4 0 KIAA1045 RING finger YyzF PF14116.6 KFM83505.1 - 0.073 13.1 6.2 24 5.0 0.1 4.1 4 0 0 4 4 4 0 YyzF-like protein zf-C2H2_2 PF12756.7 KFM83505.1 - 0.087 13.2 25.0 1.8 8.9 1.0 4.5 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) MetOD1 PF18546.1 KFM83505.1 - 0.092 12.7 9.6 1.1 9.2 0.5 3.8 2 1 2 4 4 4 0 Metanogen output domain 1 zf-C2HC_2 PF13913.6 KFM83505.1 - 0.13 12.2 11.9 7.4 6.6 0.2 4.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type DZR PF12773.7 KFM83505.1 - 0.14 12.2 6.9 17 5.6 6.9 3.0 1 1 0 1 1 1 0 Double zinc ribbon zf-DBF PF07535.12 KFM83505.1 - 0.18 11.9 16.1 11 6.2 0.1 4.8 5 0 0 5 5 5 0 DBF zinc finger zinc-ribbons_6 PF07191.12 KFM83505.1 - 0.27 11.3 10.6 2.8 8.0 4.5 3.8 1 1 2 3 3 3 0 zinc-ribbons zf-C2H2_6 PF13912.6 KFM83505.1 - 0.3 11.1 0.4 0.3 11.1 0.4 5.4 6 1 0 6 6 5 0 C2H2-type zinc finger zf-RRPl_C4 PF17026.5 KFM83505.1 - 0.34 11.0 13.4 1 9.5 6.1 2.4 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 KFM83505.1 - 0.44 10.7 7.3 3.1 8.0 0.9 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 KFM83505.1 - 0.67 9.8 17.0 9.9 6.1 0.3 4.7 2 1 3 5 5 5 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFM83505.1 - 0.88 9.8 15.4 0.38 10.9 7.2 2.9 1 1 1 2 2 2 0 FYVE zinc finger A2L_zn_ribbon PF08792.10 KFM83505.1 - 1.3 8.8 11.6 11 5.9 0.2 4.5 4 0 0 4 4 4 0 A2L zinc ribbon domain Guanylin PF02058.15 KFM83505.1 - 7.8 7.1 12.0 3.4 8.2 1.1 3.4 2 1 2 4 4 4 0 Guanylin precursor Ribosomal_60s PF00428.19 KFM83506.1 - 3.4e-08 34.0 2.7 3.8e-08 33.8 2.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2958 PF11171.8 KFM83506.1 - 0.055 13.7 0.0 0.065 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) Dioxygenase_N PF04444.14 KFM83506.1 - 0.16 11.9 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Cullin PF00888.22 KFM83507.1 - 3.4e-19 68.9 0.1 3.5e-19 68.9 0.1 1.0 1 0 0 1 1 1 1 Cullin family DUF5589 PF17672.1 KFM83507.1 - 0.13 12.2 0.2 0.17 11.9 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5589) THAP PF05485.12 KFM83508.1 - 1.6e-05 25.8 0.1 2e-05 25.4 0.1 1.1 1 0 0 1 1 1 1 THAP domain LRR_6 PF13516.6 KFM83509.1 - 1.7e-09 37.0 1.3 0.094 12.8 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 KFM83509.1 - 6.9e-07 29.5 3.2 0.04 14.4 0.4 3.1 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM83509.1 - 4.5e-05 23.4 5.0 4.9 8.1 0.1 4.6 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.6 KFM83509.1 - 0.041 13.6 4.3 4.5 7.1 1.3 3.4 2 2 1 3 3 3 0 Leucine rich repeat Gp58 PF07902.11 KFM83509.1 - 0.11 10.8 0.1 0.3 9.3 0.1 1.6 2 0 0 2 2 2 0 gp58-like protein zf-H2C2_2 PF13465.6 KFM83511.1 - 2.6e-71 233.1 76.1 2.5e-08 34.0 0.6 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83511.1 - 8.1e-52 170.9 85.4 1.1e-05 25.6 2.8 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83511.1 - 1.4e-41 137.5 80.3 0.00053 20.6 1.7 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 KFM83511.1 - 2.1e-19 69.2 68.2 0.00089 19.6 0.9 11.3 11 0 0 11 11 11 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83511.1 - 4.6e-15 55.2 63.9 0.024 14.7 1.4 11.4 11 0 0 11 11 11 6 C2H2-type zinc finger zf-MYST PF17772.1 KFM83511.1 - 1.6e-13 50.0 51.8 0.15 11.7 0.5 10.9 2 2 9 11 11 11 8 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 KFM83511.1 - 1.7e-10 40.8 31.7 0.088 12.9 0.2 10.3 7 4 4 11 11 11 3 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KFM83511.1 - 2.7e-09 37.1 59.6 0.03 14.6 0.1 10.9 10 1 1 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM83511.1 - 3e-09 36.5 51.2 0.024 14.4 0.2 10.4 10 0 0 10 10 10 6 C2H2-type zinc-finger domain BolA PF01722.18 KFM83511.1 - 1.2e-07 31.9 11.8 1.6 9.1 0.1 6.9 1 1 5 7 7 7 2 BolA-like protein DUF4825 PF16107.5 KFM83511.1 - 4.5e-06 26.7 0.2 17 5.6 0.0 5.6 2 2 4 7 7 7 0 Domain of unknown function (DUF4825) zf-C2H2_8 PF15909.5 KFM83511.1 - 3.2e-05 24.1 42.5 0.081 13.2 1.5 5.3 1 1 4 5 5 5 3 C2H2-type zinc ribbon zf-BED PF02892.15 KFM83511.1 - 9.2e-05 22.4 63.4 0.0046 16.9 2.1 9.3 2 1 7 9 9 8 4 BED zinc finger GAGA PF09237.11 KFM83511.1 - 0.00011 21.9 28.4 2 8.3 0.1 8.8 2 2 8 10 10 10 3 GAGA factor zf-DBF PF07535.12 KFM83511.1 - 0.0057 16.8 43.1 11 6.2 0.1 10.3 9 1 1 10 10 10 0 DBF zinc finger zf-C2H2_2 PF12756.7 KFM83511.1 - 0.0064 16.8 62.8 0.58 10.5 0.8 10.3 1 1 10 11 11 11 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFM83511.1 - 0.075 13.7 32.4 47 4.7 16.1 7.5 2 2 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 KFM83511.1 - 0.076 12.9 44.4 1.6 8.6 0.1 10.2 3 1 8 11 11 11 0 C2H2 type zinc-finger (1 copy) Complex1_49kDa PF00346.19 KFM83511.1 - 0.083 12.0 1.2 2.8 6.9 0.1 2.5 2 1 1 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-C2HE PF16278.5 KFM83511.1 - 0.11 13.0 0.4 0.11 13.0 0.4 7.4 4 3 5 10 10 9 0 C2HE / C2H2 / C2HC zinc-binding finger zf-RING_UBOX PF13445.6 KFM83511.1 - 0.81 9.8 25.6 1.1e+02 2.9 0.3 9.4 9 2 1 10 10 10 0 RING-type zinc-finger Thioredoxin_16 PF18569.1 KFM83511.1 - 1.4 9.1 9.3 0.87 9.7 0.5 3.8 1 1 3 5 5 5 0 Thioredoxin-like domain zinc_ribbon_15 PF17032.5 KFM83511.1 - 2.4 9.0 40.2 0.74 10.6 2.9 5.9 1 1 4 6 6 6 0 zinc-ribbon family Zf_RING PF16744.5 KFM83511.1 - 5.3 7.2 53.9 5.7 7.1 0.2 10.4 1 1 8 9 9 9 0 KIAA1045 RING finger zf-met2 PF12907.7 KFM83511.1 - 5.5 7.2 52.2 2.3 8.4 0.9 10.8 11 0 0 11 11 11 0 Zinc-binding PRP21_like_P PF12230.8 KFM83511.1 - 9.4 6.0 19.5 0.74 9.6 6.8 3.9 3 1 1 4 4 4 0 Pre-mRNA splicing factor PRP21 like protein IF3_N PF05198.16 KFM83511.1 - 9.8 6.5 6.1 26 5.2 0.1 4.2 5 0 0 5 5 5 0 Translation initiation factor IF-3, N-terminal domain 7tm_2 PF00002.24 KFM83512.1 - 6.4e-28 97.7 21.1 9.1e-28 97.2 21.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ocular_alb PF02101.15 KFM83512.1 - 0.011 14.7 0.9 0.011 14.7 0.9 2.6 2 1 1 3 3 3 0 Ocular albinism type 1 protein 7tm_1 PF00001.21 KFM83512.1 - 0.049 13.0 19.3 0.47 9.7 19.3 2.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1801 PF08818.11 KFM83512.1 - 0.087 13.3 0.1 0.47 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DU1801) 7tm_2 PF00002.24 KFM83514.1 - 9.6e-25 87.3 16.4 1.4e-24 86.7 16.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Spectrin PF00435.21 KFM83515.1 - 9.8e-07 29.2 1.5 1.1e-06 29.1 1.5 1.0 1 0 0 1 1 1 1 Spectrin repeat UBA_4 PF14555.6 KFM83516.1 - 1.8e-05 24.5 0.1 2.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KFM83516.1 - 0.0034 17.0 0.1 0.0052 16.4 0.1 1.3 1 0 0 1 1 1 1 TAP C-terminal domain Ribosomal_L10 PF00466.20 KFM83518.1 - 1.1e-07 31.9 0.1 1.1e-07 31.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L10 BA14K PF07886.11 KFM83519.1 - 0.065 13.1 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 BA14K-like protein CGI-121 PF08617.10 KFM83520.1 - 2.4e-19 70.1 0.2 2.7e-19 69.9 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Ras PF00071.22 KFM83521.1 - 3.5e-21 75.5 0.0 3.8e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM83521.1 - 4.2e-16 59.3 0.0 4.6e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM83521.1 - 2.1e-05 24.1 0.0 2.2e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family CmlA_N PF18456.1 KFM83521.1 - 0.057 12.7 0.0 0.058 12.7 0.0 1.0 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain GTP_EFTU PF00009.27 KFM83521.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Spectrin PF00435.21 KFM83523.1 - 4.2e-10 40.0 3.3 8.7e-08 32.6 0.4 2.0 2 0 0 2 2 2 2 Spectrin repeat Strumpellin PF10266.9 KFM83523.1 - 0.053 11.2 0.6 0.064 11.0 0.6 1.0 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin Phage_GP20 PF06810.11 KFM83523.1 - 0.065 13.0 0.1 0.084 12.7 0.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Mating_N PF12731.7 KFM83523.1 - 0.077 13.1 0.2 0.79 9.9 0.2 2.0 1 1 1 2 2 2 0 Mating-type protein beta 1 DDE_Tnp_4 PF13359.6 KFM83524.1 - 1.6e-11 44.1 1.1 2.3e-11 43.6 1.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFM83524.1 - 6.2e-08 32.5 0.0 7.4e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 KFM83524.1 - 0.057 13.8 0.2 0.093 13.1 0.2 1.5 1 1 0 1 1 1 0 Transposase DDE domain FAR1 PF03101.15 KFM83526.1 - 0.043 14.5 1.2 0.07 13.8 1.2 1.4 1 1 0 1 1 1 0 FAR1 DNA-binding domain EGF PF00008.27 KFM83528.1 - 7.9e-06 26.1 16.3 0.0017 18.6 11.4 2.3 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFM83528.1 - 0.0069 17.0 6.1 0.0069 17.0 6.1 2.7 3 1 0 3 3 3 1 Human growth factor-like EGF EGF_2 PF07974.13 KFM83528.1 - 0.077 13.4 16.3 0.88 10.0 7.6 2.2 2 0 0 2 2 2 0 EGF-like domain adh_short PF00106.25 KFM83532.1 - 0.003 17.0 0.6 0.0036 16.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase STALD PF18185.1 KFM83532.1 - 0.14 11.5 0.1 0.14 11.4 0.1 1.0 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family DNA_pol_A_exo1 PF01612.20 KFM83533.1 - 3e-10 40.1 0.1 6.8e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRM PF02793.22 KFM83534.1 - 2.8e-05 24.3 0.2 3.7e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Hormone receptor domain BAR_3 PF16746.5 KFM83535.1 - 2.4e-10 40.5 0.0 2.6e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 BAR domain of APPL family ATP_bind_1 PF03029.17 KFM83536.1 - 1.4e-14 54.5 0.0 1.5e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein 7tm_2 PF00002.24 KFM83538.1 - 1.2e-24 86.9 13.9 1.9e-24 86.3 13.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 KFM83538.1 - 1.4e-05 24.5 12.2 1.8e-05 24.2 11.4 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 KFM83538.1 - 0.00031 19.9 12.3 0.00038 19.6 10.3 2.2 2 1 0 2 2 2 1 Frizzled/Smoothened family membrane region Ocular_alb PF02101.15 KFM83538.1 - 0.0012 17.8 5.2 0.0026 16.8 5.1 1.4 1 1 0 1 1 1 1 Ocular albinism type 1 protein PMT_4TMC PF16192.5 KFM83538.1 - 0.0038 16.8 9.0 0.0075 15.9 3.8 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase Pinin_SDK_N PF04697.13 KFM83539.1 - 4.4e-06 27.4 0.0 4.5e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 pinin/SDK conserved region SbsC_C PF18058.1 KFM83539.1 - 0.064 13.5 0.0 0.068 13.4 0.0 1.0 1 0 0 1 1 1 0 SbsC C-terminal domain Ldl_recept_b PF00058.17 KFM83540.1 - 2.4e-05 24.7 0.1 0.013 16.0 0.0 2.0 2 0 0 2 2 2 2 Low-density lipoprotein receptor repeat class B 7tm_2 PF00002.24 KFM83542.1 - 3.2e-12 46.3 0.7 3.3e-12 46.2 0.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) ArAE_2_N PF10337.9 KFM83542.1 - 0.03 13.4 0.8 0.032 13.3 0.8 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Phospholip_B PF04916.13 KFM83543.1 - 1.3e-16 60.3 0.1 1.5e-16 60.1 0.1 1.0 1 0 0 1 1 1 1 Phospholipase B RVT_1 PF00078.27 KFM83544.1 - 1.9e-20 73.3 0.0 2.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SLC3A2_N PF16028.5 KFM83545.1 - 9.7e-33 111.6 1.4 1.5e-32 111.0 1.4 1.3 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Alpha-amylase PF00128.24 KFM83545.1 - 3.4e-08 33.4 0.1 4.9e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Plasmod_Pvs28 PF06247.11 KFM83546.1 - 0.035 14.4 17.7 0.045 14.0 17.7 1.2 1 0 0 1 1 1 0 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 KFM83546.1 - 0.63 10.1 13.1 0.76 9.9 13.1 1.1 1 0 0 1 1 1 0 MSP1 EGF domain 1 Sec3-PIP2_bind PF15277.6 KFM83548.1 - 0.02 15.0 0.2 10 6.4 0.0 3.0 2 1 1 3 3 3 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PuR_N PF09182.10 KFM83548.1 - 0.13 12.2 5.2 21 5.1 0.1 3.8 1 1 3 4 4 4 0 Bacterial purine repressor, N-terminal PWWP PF00855.17 KFM83549.1 - 0.015 15.7 2.9 0.042 14.3 2.9 1.8 1 1 0 1 1 1 0 PWWP domain NOA36 PF06524.12 KFM83549.1 - 0.069 12.5 4.2 0.11 11.9 4.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2722 PF10846.8 KFM83549.1 - 0.68 8.8 4.1 0.93 8.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FXa_inhibition PF14670.6 KFM83550.1 - 6e-18 64.8 19.0 3.6e-11 43.2 5.2 2.1 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFM83550.1 - 8e-14 51.3 4.5 2.6e-08 33.7 0.4 2.6 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFM83550.1 - 1.2e-10 41.4 18.0 3e-09 36.9 6.1 2.2 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF PF00008.27 KFM83550.1 - 6.5e-09 35.9 18.8 5.9e-05 23.3 6.6 2.4 3 0 0 3 3 3 2 EGF-like domain EGF_3 PF12947.7 KFM83550.1 - 2e-07 31.0 17.5 0.002 18.3 1.4 3.1 2 1 0 2 2 2 2 EGF domain hEGF PF12661.7 KFM83550.1 - 0.013 16.1 3.0 0.013 16.1 3.0 3.4 3 1 0 3 3 3 0 Human growth factor-like EGF Tme5_EGF_like PF09064.10 KFM83550.1 - 0.14 12.0 13.8 0.5 10.3 1.2 2.3 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like EGF_2 PF07974.13 KFM83550.1 - 1.2 9.6 17.7 2.7 8.5 2.5 2.7 2 1 0 2 2 2 0 EGF-like domain Plasmod_Pvs28 PF06247.11 KFM83550.1 - 7.4 7.0 14.9 7.8 6.9 8.3 2.9 1 1 1 2 2 2 0 Pvs28 EGF domain ECR1_N PF14382.6 KFM83551.1 - 0.13 12.0 0.2 0.48 10.3 0.0 1.9 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region Spectrin PF00435.21 KFM83553.1 - 1.2e-08 35.3 6.8 0.00014 22.3 1.9 2.0 2 0 0 2 2 2 2 Spectrin repeat W2 PF02020.18 KFM83553.1 - 0.025 14.7 0.7 0.043 13.9 0.7 1.6 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Zmiz1_N PF18028.1 KFM83553.1 - 0.056 13.8 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Zmiz1 N-terminal tetratricopeptide repeat domain RL10P_insert PF17777.1 KFM83555.1 - 2.2e-21 75.6 0.2 2.9e-21 75.2 0.2 1.2 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P NPP PF08384.10 KFM83559.1 - 0.34 11.0 1.7 1.3 9.2 1.7 2.1 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region Vinculin PF01044.19 KFM83560.1 - 1.8e-15 56.3 0.2 1.9e-15 56.2 0.2 1.0 1 0 0 1 1 1 1 Vinculin family He_PIG_assoc PF10632.9 KFM83560.1 - 0.16 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Dynein_heavy PF03028.15 KFM83564.1 - 3.3e-42 143.3 0.0 4.6e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KFM83564.1 - 1.2e-19 70.7 0.0 1.9e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Peptidase_M1_N PF17900.1 KFM83565.1 - 0.027 14.7 0.0 0.048 13.8 0.0 1.4 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain DUF4817 PF16087.5 KFM83566.1 - 1.6e-06 27.8 0.2 3.5e-06 26.7 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_18 PF12833.7 KFM83566.1 - 0.15 12.4 2.0 5.4 7.3 0.1 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain 7tm_1 PF00001.21 KFM83567.1 - 5.9e-06 25.8 0.4 5.9e-06 25.8 0.4 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM83567.1 - 0.00069 19.1 0.6 0.001 18.5 0.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4436 PF14494.6 KFM83567.1 - 0.1 11.9 0.3 0.096 12.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) tRNA_m1G_MT PF01746.21 KFM83571.1 - 6e-21 75.0 0.0 6.6e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase zf-H2C2_2 PF13465.6 KFM83574.1 - 1.5e-75 246.5 102.0 4.4e-07 30.0 0.6 15.3 15 0 0 15 15 15 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83574.1 - 4.7e-59 193.7 114.8 4.5e-05 23.7 0.8 15.1 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83574.1 - 1.5e-52 171.7 106.3 0.00033 21.2 0.6 15.2 15 0 0 15 15 15 15 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM83574.1 - 3.9e-39 132.2 83.1 0.00033 20.8 0.1 15.0 15 0 0 15 15 15 14 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM83574.1 - 2.4e-36 123.1 93.1 0.00049 20.4 1.8 15.4 14 1 2 16 16 16 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFM83574.1 - 3.1e-14 52.6 99.9 0.00096 19.1 0.2 16.4 17 0 0 17 17 16 12 C2H2-type zinc finger zf-Di19 PF05605.12 KFM83574.1 - 1.6e-08 34.7 77.8 0.061 13.6 3.3 9.5 3 3 7 11 11 11 9 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFM83574.1 - 1.6e-06 28.3 16.2 3.8 7.8 0.1 7.9 5 3 4 9 9 9 3 BolA-like protein zf_UBZ PF18439.1 KFM83574.1 - 0.0019 17.8 53.4 0.37 10.4 0.1 11.8 12 0 0 12 12 12 4 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KFM83574.1 - 0.0039 17.1 61.8 0.031 14.2 0.1 13.2 15 0 0 15 15 15 4 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFM83574.1 - 0.011 16.4 50.1 0.039 14.7 1.1 7.4 2 2 1 6 6 6 0 zinc-ribbon family WAC_Acf1_DNA_bd PF10537.9 KFM83574.1 - 0.31 11.6 4.7 2.9 8.5 0.3 3.5 4 0 0 4 4 4 0 ATP-utilising chromatin assembly and remodelling N-terminal GAGA PF09237.11 KFM83574.1 - 6 6.8 0.0 6 6.8 0.0 8.7 4 2 8 12 12 12 0 GAGA factor FYDLN_acid PF09538.10 KFM83574.1 - 6.7 7.5 23.9 2.7 8.7 0.1 8.0 2 1 7 10 10 10 0 Protein of unknown function (FYDLN_acid) MBT PF02820.18 KFM83575.1 - 4.9e-23 81.3 0.0 5.9e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 mbt repeat Transferrin PF00405.17 KFM83576.1 - 1.7e-64 218.1 0.3 2e-64 217.9 0.3 1.0 1 0 0 1 1 1 1 Transferrin CoA_trans PF01144.23 KFM83578.1 - 3.6e-05 23.3 0.0 3.7e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase zf-H2C2_2 PF13465.6 KFM83580.1 - 6.3e-26 89.6 55.9 7.4e-09 35.6 3.8 6.4 6 1 1 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFM83580.1 - 6.9e-11 42.0 63.8 0.00026 21.3 3.8 6.1 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFM83580.1 - 4.3e-10 39.6 57.7 0.0044 17.7 0.4 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFM83580.1 - 1.3e-06 28.6 30.6 0.039 14.2 0.6 5.6 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFM83580.1 - 0.00093 18.9 4.9 0.00093 18.9 4.9 6.2 5 2 0 5 5 5 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFM83580.1 - 0.015 15.7 6.2 0.058 13.8 0.6 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFM83580.1 - 3.9 7.8 22.4 8.5 6.7 9.2 3.1 1 1 2 3 3 3 0 C2H2-type zinc ribbon FYDLN_acid PF09538.10 KFM83580.1 - 4.2 8.1 10.3 42 4.9 0.1 4.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_15 PF17032.5 KFM83580.1 - 4.8 8.0 22.5 55 4.6 6.4 4.0 2 1 1 3 3 3 0 zinc-ribbon family FIBP PF05427.11 KFM83581.1 - 1e-14 54.6 0.2 1.1e-14 54.6 0.2 1.0 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) PI3Ka PF00613.20 KFM83583.1 - 1.9e-15 56.7 0.0 2.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Vac_Fusion PF02346.16 KFM83584.1 - 0.037 13.6 0.1 0.037 13.6 0.1 1.1 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 DUF4806 PF16064.5 KFM83585.1 - 0.076 13.3 0.0 0.23 11.7 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4806) RPAP1_N PF08621.10 KFM83585.1 - 0.091 12.5 0.1 3 7.7 0.0 2.2 2 0 0 2 2 2 0 RPAP1-like, N-terminal HD_3 PF13023.6 KFM83590.1 - 3.1e-28 98.8 0.5 3.8e-28 98.5 0.5 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KFM83590.1 - 8e-08 32.2 0.4 9.8e-08 32.0 0.4 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KFM83590.1 - 0.032 14.5 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 HD domain Cation_ATPase_N PF00690.26 KFM83593.1 - 4e-20 71.3 0.0 5e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF872 PF05915.12 KFM83593.1 - 0.14 12.4 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Pkinase PF00069.25 KFM83595.1 - 4.6e-10 39.3 0.0 4.6e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM83595.1 - 2.4e-07 30.3 0.0 2.6e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM83595.1 - 0.03 13.6 0.0 0.032 13.6 0.0 1.0 1 0 0 1 1 1 0 Kinase-like I-set PF07679.16 KFM83596.1 - 2.8e-27 94.6 2.1 1.8e-13 50.3 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFM83596.1 - 1.9e-17 63.6 0.0 3e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFM83596.1 - 3.9e-14 52.7 0.0 8.6e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFM83596.1 - 2.3e-12 46.9 0.0 9.5e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFM83596.1 - 4.1e-08 33.4 0.7 0.00095 19.3 0.1 3.4 2 2 1 3 3 3 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFM83596.1 - 3.3e-05 23.9 0.1 0.012 15.6 0.0 2.3 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFM83596.1 - 0.00011 22.5 0.2 0.018 15.4 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFM83596.1 - 0.00013 22.1 0.9 0.058 13.7 0.1 3.1 2 2 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFM83596.1 - 0.001 19.4 0.5 0.22 12.0 0.1 2.9 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set PF05790.15 KFM83596.1 - 0.0093 16.1 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin C2-set domain Ig_6 PF18452.1 KFM83596.1 - 0.0097 15.5 0.0 0.032 13.8 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Herpes_gE PF02480.16 KFM83596.1 - 0.0099 14.7 0.1 0.01 14.6 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E UL141 PF16758.5 KFM83596.1 - 0.056 13.2 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Herpes-like virus membrane glycoprotein UL141 BiPBP_C PF06832.12 KFM83596.1 - 0.085 12.9 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family C2-set_2 PF08205.12 KFM83596.1 - 0.16 12.0 0.0 0.84 9.7 0.0 2.2 2 1 1 3 3 3 0 CD80-like C2-set immunoglobulin domain p450 PF00067.22 KFM83597.1 - 1.9e-23 83.0 0.0 2e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 KFM83598.1 - 0.00019 21.2 0.0 0.00019 21.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region HTH_48 PF17906.1 KFM83599.1 - 3.9e-14 52.5 0.0 5.8e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_23 PF13384.6 KFM83599.1 - 0.019 14.7 0.0 0.093 12.6 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DUF4817 PF16087.5 KFM83599.1 - 0.034 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) AalphaY_MDB PF04611.12 KFM83600.1 - 0.0023 17.9 0.3 0.0025 17.8 0.3 1.1 1 0 0 1 1 1 1 Mating type protein A alpha Y mating type dependent binding region DUF5595 PF18077.1 KFM83600.1 - 0.1 12.7 17.0 1.2 9.3 6.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) ZnuA PF01297.17 KFM83600.1 - 0.12 11.8 5.7 0.1 12.0 4.2 1.5 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic T3SS_needle_F PF09392.10 KFM83600.1 - 0.16 12.2 3.9 3.9 7.8 0.2 2.1 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF MMR_HSR1_C PF08438.10 KFM83600.1 - 0.18 12.4 4.6 0.22 12.1 4.6 1.3 1 0 0 1 1 1 0 GTPase of unknown function C-terminal AcylCoA_dehyd_C PF12186.8 KFM83600.1 - 0.37 10.9 5.9 0.28 11.3 4.6 1.5 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal YlqD PF11068.8 KFM83600.1 - 0.48 10.8 11.9 0.59 10.5 11.9 1.0 1 0 0 1 1 1 0 YlqD protein PIN_8 PF18476.1 KFM83600.1 - 0.77 9.6 10.5 0.84 9.4 10.5 1.0 1 0 0 1 1 1 0 PIN like domain DUF4404 PF14357.6 KFM83600.1 - 5.3 7.8 11.5 5 7.8 4.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Seadorna_VP6 PF07407.11 KFM83600.1 - 7.3 5.4 8.3 7.6 5.4 8.3 1.0 1 0 0 1 1 1 0 Seadornavirus VP6 protein AAA_11 PF13086.6 KFM83600.1 - 8.4 6.1 12.4 9 6.0 12.4 1.0 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 KFM83600.1 - 9.9 5.3 12.7 11 5.2 12.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein Spy1 PF11357.8 KFM83602.1 - 0.11 12.8 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Cell cycle regulatory protein DUF3836 PF12930.7 KFM83602.1 - 0.22 11.3 0.8 0.23 11.2 0.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF3836) ArfA PF03889.13 KFM83602.1 - 0.39 10.2 0.1 0.39 10.2 0.1 1.6 2 0 0 2 2 2 0 Alternative ribosome-rescue factor A Kunitz_BPTI PF00014.23 KFM83604.1 - 1.5e-56 188.4 31.5 2.2e-20 72.6 1.4 3.1 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain tRNA-synt_1b PF00579.25 KFM83605.1 - 6.2e-18 65.1 0.0 6.8e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) EndIII_4Fe-2S PF10576.9 KFM83606.1 - 4.9e-07 29.9 4.8 6.2e-07 29.6 4.8 1.2 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Whib PF02467.16 KFM83606.1 - 0.096 13.3 0.3 0.11 13.1 0.3 1.2 1 0 0 1 1 1 0 Transcription factor WhiB DBINO PF13892.6 KFM83608.1 - 0.00035 20.9 16.5 0.00039 20.8 16.5 1.1 1 0 0 1 1 1 1 DNA-binding domain HATPase_c_4 PF13749.6 KFM83608.1 - 0.03 14.5 1.1 0.27 11.4 1.2 2.0 1 1 1 2 2 2 0 Putative ATP-dependent DNA helicase recG C-terminal Beta_elim_lyase PF01212.21 KFM83608.1 - 0.034 13.4 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase OmpH PF03938.14 KFM83608.1 - 0.094 13.0 9.0 0.11 12.9 9.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CP12 PF02672.15 KFM83608.1 - 0.24 12.2 5.4 0.27 12.0 4.5 1.6 1 1 0 1 1 1 0 CP12 domain DnaT PF17948.1 KFM83608.1 - 0.26 11.0 4.7 0.6 9.8 0.7 2.2 2 0 0 2 2 2 0 DnaT DNA-binding domain DUF2335 PF10097.9 KFM83608.1 - 6.6 6.8 10.2 0.26 11.3 2.8 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2335) Laminin_G_2 PF02210.24 KFM83610.1 - 2.3e-33 115.5 0.0 7.2e-30 104.2 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFM83610.1 - 3.2e-24 85.6 0.0 3e-23 82.5 0.0 2.1 2 0 0 2 2 2 1 Laminin G domain EGF PF00008.27 KFM83610.1 - 0.0021 18.3 4.1 0.0045 17.3 4.1 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFM83610.1 - 0.0053 17.4 2.8 0.012 16.3 2.8 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.13 KFM83610.1 - 0.11 12.9 6.8 0.19 12.1 6.8 1.4 1 0 0 1 1 1 0 EGF-like domain Laminin_G_3 PF13385.6 KFM83610.1 - 0.12 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Collagen PF01391.18 KFM83612.1 - 0.00012 21.8 14.2 0.00017 21.3 14.2 1.3 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) SMN PF06003.12 KFM83612.1 - 0.72 9.1 3.3 0.75 9.0 3.3 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) E1_DerP2_DerF2 PF02221.15 KFM83614.1 - 6.2e-07 29.9 0.1 1.5e-06 28.7 0.1 1.7 1 1 0 1 1 1 1 ML domain Lipoprotein_8 PF02030.15 KFM83615.1 - 0.032 13.0 0.8 0.037 12.7 0.8 1.1 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) DUF4473 PF14747.6 KFM83616.1 - 0.15 12.7 0.1 0.18 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Cupin_8 PF13621.6 KFM83617.1 - 7.6e-13 48.8 0.0 9.2e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain SatD PF16264.5 KFM83617.1 - 0.024 14.2 0.3 0.044 13.4 0.2 1.3 1 1 0 1 1 1 0 SatD family (SatD) Mucin2_WxxW PF13330.6 KFM83619.1 - 0.35 11.7 4.3 0.29 12.0 0.4 2.5 2 0 0 2 2 2 0 Mucin-2 protein WxxW repeating region Med12-LCEWAV PF12145.8 KFM83624.1 - 2.5e-14 53.0 1.7 2.6e-14 53.0 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Na_Ca_ex PF01699.24 KFM83625.1 - 3e-26 92.2 16.6 3e-26 92.2 16.6 1.7 2 0 0 2 2 2 1 Sodium/calcium exchanger protein DUF2527 PF10736.9 KFM83625.1 - 0.094 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Syntaxin PF00804.25 KFM83626.1 - 0.00022 21.0 8.4 0.00024 20.8 8.4 1.2 1 0 0 1 1 1 1 Syntaxin FUSC PF04632.12 KFM83626.1 - 0.54 8.7 1.4 0.58 8.6 1.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family 2-Hacid_dh_C PF02826.19 KFM83629.1 - 9.7e-26 90.2 0.0 9.9e-26 90.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFM83629.1 - 0.0024 18.1 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KFM83629.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KFM83629.1 - 0.16 12.5 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ribonuclease_3 PF00636.26 KFM83630.1 - 9.9e-61 202.9 0.3 6.3e-35 120.0 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease III domain PAZ PF02170.22 KFM83630.1 - 1e-36 125.7 1.3 2.2e-36 124.7 1.3 1.6 1 0 0 1 1 1 1 PAZ domain Ribonucleas_3_3 PF14622.6 KFM83630.1 - 5.9e-26 91.1 0.0 5.6e-17 62.1 0.0 3.7 3 1 0 3 3 3 2 Ribonuclease-III-like SK_channel PF03530.14 KFM83631.1 - 2.7e-05 24.1 6.2 3.4e-05 23.8 0.3 2.3 2 1 0 2 2 2 2 Calcium-activated SK potassium channel Thioredoxin_2 PF13098.6 KFM83632.1 - 1.5e-06 28.6 0.2 0.015 15.8 0.1 3.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFM83632.1 - 5.6e-06 26.3 0.0 0.052 13.5 0.0 2.3 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 KFM83632.1 - 0.00035 20.8 0.1 0.17 12.3 0.0 3.0 2 2 1 3 3 3 1 Thioredoxin-like HyaE PF07449.11 KFM83632.1 - 0.00083 19.3 0.1 0.25 11.3 0.1 2.5 1 1 1 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 KFM83632.1 - 0.0012 18.6 0.7 0.62 9.7 0.0 2.5 3 0 0 3 3 3 2 Thioredoxin DUF3798 PF12683.7 KFM83632.1 - 0.033 13.6 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3798) KaiB PF07689.12 KFM83632.1 - 0.064 13.0 0.0 1.3 8.8 0.0 2.7 2 2 1 3 3 3 0 KaiB domain W2 PF02020.18 KFM83632.1 - 0.12 12.5 1.8 0.2 11.8 1.2 1.7 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon DeoC PF01791.9 KFM83632.1 - 0.18 11.4 0.1 19 4.8 0.0 2.1 2 0 0 2 2 2 0 DeoC/LacD family aldolase TrbC_Ftype PF09673.10 KFM83632.1 - 0.19 11.8 0.0 4.1 7.5 0.0 2.3 2 1 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein 7tm_1 PF00001.21 KFM83634.1 - 2.6e-73 246.6 8.7 4.6e-73 245.8 8.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFM83634.1 - 1.4e-10 41.0 5.9 9.8e-09 35.0 1.9 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFM83634.1 - 3.4e-06 27.0 3.4 3.4e-06 27.0 3.4 1.7 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFM83634.1 - 1.1e-05 25.2 8.2 3e-05 23.8 8.2 1.7 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TMEM192 PF14802.6 KFM83634.1 - 0.07 12.2 0.3 0.54 9.3 0.0 2.2 2 0 0 2 2 2 0 TMEM192 family S_4TM PF18159.1 KFM83634.1 - 0.076 12.3 2.2 0.078 12.3 0.0 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain 7TM_GPCR_Srbc PF10316.9 KFM83634.1 - 0.32 10.5 16.3 2.7 7.4 16.3 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chelicerata/Stegodyphus_mimosarum-v1/GCA_000611955.2_Stegodyphus_mimosarum_v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chelicerata/Stegodyphus_mimosarum-v1/GCA_000611955.2_Stegodyphus_mimosarum_v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chelicerata/Stegodyphus_mimosarum-v1/GCA_000611955.2_Stegodyphus_mimosarum_v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chelicerata/Stegodyphus_mimosarum-v1/GCA_000611955.2_Stegodyphus_mimosarum_v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 19:46:00 2019 # [ok]